LOCUS       DAJVKX010000001       111981 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000001 DAJVKX010000000
VERSION     DAJVKX010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 111981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 111981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..111981
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.001"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            518..1585
                     /locus_tag="OPY25_000001"
     CDS             518..1585
                     /locus_tag="OPY25_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HCS0925740.1"
                     /translation="MDKMKRHLVWWGAGILVAVAAIAWWMLRPAGIPEGFAASNGRIE
                     ATEVDIATKIAGRIDTILVSEGQFVRQGEVLAKMDTRVLQEQRLEAIAQIKEAESAVA
                     AARALLEQRQSEMRAAQSVVKQREAELDSVSKRHVRSRSLSQRGAVSVQQLDDDRAAA
                     ESARAALETAKAQVSAAKAAIEAARTSIIQAQTRVEAAQATERRIVADIDDSELKAPR
                     DGRVQYRVAEPGEVLSAGGRVLNMVDLSDVYMTFFLPTEQAGLLKIGGDARLVLDAAP
                     DLRIPATISFVASVAQFTPKTVETHDERLKLMFRVKARIPPELLRQHLEYVKTGLPGM
                     AWVRLDERVPWPDDLNVRLSQ"
     gene            1582..4323
                     /gene="rbbA"
                     /locus_tag="OPY25_000002"
     CDS             1582..4323
                     /gene="rbbA"
                     /locus_tag="OPY25_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HCS0925741.1"
                     /translation="MTSLTLVPVPPVAQLEGVSQHYGKTVALNNITLDIPARSMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVIVLGGDMRDAKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREARITELLNSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDSLSRAQFWDLIDSIRQRQTNMSVLVATAYMEEAERFDWL
                     VAMNAGEILATGSAQQLRAKTHSATLEQAFIALLPEAQRQAHKPVVIPPYHAEQEEIA
                     IEAKDLTMRFGKFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGQAW
                     LFGQPVDPNDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPPAEIPARVAQMI
                     ERFMLTEVEDTLPASLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRMSLMHAGKVLASGTPQELVQQRGAANLEAAFI
                     SWLQEAAGAAPETPIPPSQTPAASDKPSRQGLSFRRLFSYSRREALELRRDPVRSTLA
                     LLGTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWSLNLAGSRYFIEQPPLASYD
                     ELDRRMRSGELAVAIEIPPNFGRDIARGTPAQIGVWVDGAMPSRAETVKGYVQAMHQS
                     WLQEAASRQPNPVKQTGLLNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSV
                     VREKELGPMINLYVTPTTRSEFLLGKQLPYIALGMLNFLLLCALSVFVFGVPLKGSFL
                     TLTLAALLYVIIATGLGLLISTFMKSQIAAIFGTSIITLIPATQFSGMIDPVASLEGP
                     GRWIGEIYPTSHFLTIARGTFSKALDLSDLWSLFMPLLIAVPVVMGLSILLLKKQEG"
     gene            4323..5442
                     /locus_tag="OPY25_000003"
                     /pseudo
     CDS             4323..5442
                     /locus_tag="OPY25_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462486.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(5547..5948)
                     /gene="nikR"
                     /locus_tag="OPY25_000004"
     CDS             complement(5547..5948)
                     /gene="nikR"
                     /locus_tag="OPY25_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HCS0925742.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRGALAQEA
                     TQEHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(6039..6617)
                     /gene="acpT"
                     /locus_tag="OPY25_000005"
     CDS             complement(6039..6617)
                     /gene="acpT"
                     /locus_tag="OPY25_000005"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HCS0925743.1"
                     /translation="MYQIVLGKVSTLSAGQLPDALIAQAPQGVRRASWLAGRVLLSRA
                     LSPLPEMVYGEQGKPAFSAGTPLWFNLSHSGDTIALLLSDEGEVGCDIEVIRPRDNWR
                     SLANAVFSLGEHAEMEAERPERQLAAFWRIWTRKEAIVKQRGGSAWQIVSVDSTLPSA
                     LSVSQCQLDTLSLAVCTPTPFTLTPQTITKAL"
     gene            complement(6669..7718)
                     /locus_tag="OPY25_000006"
     CDS             complement(6669..7718)
                     /locus_tag="OPY25_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCS0925744.1"
                     /translation="MATAQPDKTGMHILLKLASLVIILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVKRPLAITIVVVVMLIVLTALVGVLAASLNEFIAMLPKYSKELT
                     RKVLHLQELMPFLNLHMSPERMLRGMDSDKIMLFTTTLMTGVSGAMASIVLLVMTVVF
                     MLFEVRHVPYKLRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGAIIWLGLALM
                     DIQFALMWGVLAFLLNYVPNIGSVISAVPPMIQALLFNGFYECVLVGALFLVVHMVIG
                     NIMEPRMMGHRLGMSTLVVFLSLLVWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            7808..9067
                     /locus_tag="OPY25_000007"
     CDS             7808..9067
                     /locus_tag="OPY25_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462482.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0925745.1"
                     /translation="MIEKKTCCKNAVILMPEPVAEPALNGLRLNLRIVSIVMFNFASY
                     LTIGLPLAVLPGYVHDAMGFSAFWAGLIISLQYFATLLSRPHAGRYADVLGPKKIVVF
                     GLCGCFLSGLGYLLADIASAWPMINLLLLGLGRVILGIGQSFAGTGSTLWGVGVVGSL
                     HIGRVISWNGIVTYGAMAMGAPLGVLCYAWGGLQGLALTVMGVALLAVLLALPRPSVK
                     ANKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSV
                     AFVGTRLLFPNGINRLGGLNVAMICFGVEIIGLLLVGTAAMPWMAKIGVLLTGMGFSL
                     VFPALGVVAVKAVPPQNQGAALATYTVFMDMSLGVTGPLAGLVMTWAGVPVIYLAAAG
                     LVAMALLLTWRLKKRPPSALPEAASSS"
     gene            complement(9071..9628)
                     /locus_tag="OPY25_000008"
     CDS             complement(9071..9628)
                     /locus_tag="OPY25_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB family lipoprotein"
                     /protein_id="HCS0925746.1"
                     /translation="MRNLVKYAGIGLLVMGLAACDNNDTKASAESAAAESQASGQPIS
                     LMDGKLSFSLPADMTDQSGKLGTQANNMHVYSDPTGQKAVIVIVGDNTDEALPVLANR
                     LLEQQRSRDPQLQVVTNKSIELKGHTLQQLDSIISAKGQTAYSSIVLGKVDNQLLTIQ
                     VTLPADNQQKAQTTAENIINTLVIK"
     gene            complement(9701..10366)
                     /locus_tag="OPY25_000009"
     CDS             complement(9701..10366)
                     /locus_tag="OPY25_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HCS0925747.1"
                     /translation="MTPFTQSQRIKALFWLSLFHLLVIISSNYLVQLPITIFGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLVSYVVSSLFYMGAWQGFAALA
                     NFNLFVARIAAASFMAYALGQILDVHVFNRLRQNRRWWLAPTASTLFGNISDTLAFFF
                     IAFWRSPDAFMAGHWMEIALVDYCFKVLISIIFFLPMYGVLLNMLLKKLADKSEISPL
                     PAS"
     gene            10536..10781
                     /gene="tusA"
                     /locus_tag="OPY25_000010"
     CDS             10536..10781
                     /gene="tusA"
                     /locus_tag="OPY25_000010"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HCS0925748.1"
                     /translation="MSDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQTGETLLIIAD
                     DPATTRDIPGFCTFMEHDLLAQETEGLPYRYLLRKAH"
     gene            complement(10805..12448)
                     /locus_tag="OPY25_000011"
     CDS             complement(10805..12448)
                     /locus_tag="OPY25_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis citrate transducer"
                     /protein_id="HCS0925749.1"
                     /translation="MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASA
                     LSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEK
                     HFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
                     DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLL
                     RPLQRIMAHIQTIADGDLTHEIEAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSI
                     YTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTDNARQATGLAKTASE
                     TARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQG
                     RGFAVVAGEVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTR
                     VTDIMGEIASASDEQSKGIEQVAQAVSEMDSVTQQNASLVEESAAAAAALEDQANELR
                     QAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF"
     gene            complement(12645..14843)
                     /gene="zntA"
                     /locus_tag="OPY25_000012"
     CDS             complement(12645..14843)
                     /gene="zntA"
                     /locus_tag="OPY25_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HCS0925750.1"
                     /translation="MSTPDTDGKKVPPFTSFRLAPAIQKADSCCCEEHCASSAPVSTA
                     VAGTRYTWKISGMDCAACARKVENAVRQIRGVNQAQVLFATEKLVVDADTDLRAQIEH
                     AVQKAGYTLRSEDSRDAAPESRLKENLPLITLIIMMAISWGLEQFNHPFGQLAFIVTT
                     LVGLYPIARQALRLMKSGSWFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARKGVSALMALKPETATRLRDGVREEVAINTLRPGDIIEVAAGGRLPADGKLV
                     SGFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILTLIE
                     EAEERRAPIERFIDRFSRIYTPVIMVIALLVTLIPPLMFDGGWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRITQVAFDKTGTLTIGKPRVTA
                     IHPASGISEAELLALAAAVEQGATHPLAQAIVREAQTRDLAIPTAESQRTLAGTGIEA
                     QVNGERILICAAGKQPAAAFAGQISELENAGQTVVLVLRNETVVGVLALQDTLRDDAR
                     DAIRELHQLGVNGVILTGDNPRAAAAIAGELDLAFKTGLLPEDKVRAVTALNQQAPLA
                     MVGDGINDAPAMKAASIGIAMGSGTDVALETADAALTHNRLRGLAQMITLARATHANI
                     RQNITIALGLKAIFLVTTLLGFTGLWLAILADTGATVLVTANALRLLRKN"
     gene            complement(14924..15550)
                     /locus_tag="OPY25_000013"
     CDS             complement(14924..15550)
                     /locus_tag="OPY25_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HCS0925751.1"
                     /translation="MLWSFIAVCLSAWLYVDASYRGPAWQRWVFKPVTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLVGDALTLLPRQRLLYAVGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLALLIVGALLIAVIWTRLEELRWPVCTFIAMTLVMVWLAGELWFFRPTAPALS
                     AFTGATLLFIGNIVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            15692..16063
                     /locus_tag="OPY25_000014"
     CDS             15692..16063
                     /locus_tag="OPY25_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HCS0925752.1"
                     /translation="MSKPPLFFIIIIALIVVAASFRFVQQRREKAANEAAPLQQKQVV
                     VSNKREKPVNDRRSRQQEVSPAGTSMRYEASFKPLNGGLEKTFRLQAQQYHALTVGDQ
                     GTLSYKGTRFVGFVSRTPDNE"
     gene            complement(16085..16354)
                     /locus_tag="OPY25_000015"
     CDS             complement(16085..16354)
                     /locus_tag="OPY25_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HCS0925753.1"
                     /translation="MLINLGRLLMLFVWAFLILNLVHPFPRPLNIFVNVALVFMALMH
                     GMQLALLKSTIPKAGPQMTTGEKIRIFLFSVFELLVWQKKFKNKK"
     gene            complement(16344..16940)
                     /gene="rsmD"
                     /locus_tag="OPY25_000016"
     CDS             complement(16344..16940)
                     /gene="rsmD"
                     /locus_tag="OPY25_000016"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HCS0925754.1"
                     /translation="MKKPTHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVMVDAHCLDCFAGSGALGLEALSRYAAQATLLEMDRAVSQQLQKNLATLKANN
                     ARVVNTNTLAFLSQPGTPHHVVFVDPPFRKGLLEETLQLLETQGWLADDALIYVESEV
                     ENGLPPVPANWALYREKVAGQVAYRLYQRDAQGENDVD"
     gene            17066..18541
                     /gene="ftsY"
                     /locus_tag="OPY25_000017"
     CDS             17066..18541
                     /gene="ftsY"
                     /locus_tag="OPY25_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCS0925755.1"
                     /translation="MAKQKKRGFFSWLGFGDKEQKQEQTEEQQIVEEQRPVEPPVETA
                     ADVDAQTPAHSKAETEAFAEEVVDVTEKVQESEKPQPVEPEPTAAIEMAAPQIAVERE
                     ELPLPEEVKDEAISPEEWQAEAETVEVIAAVEEEGENAAKFTDEELEAQALAAQAAEE
                     AVMVVPPAEEDAPVEAIVQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKID
                     DDLFEELEEQLLIADVGVETTRKIIANLTEGASRKQLKDAEALYGLLKDEMGEILAKV
                     DEPLNIEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQL
                     QVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNVDVLIADTAGRLQNKSHLMEELK
                     KIVRVMKKLDEEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGV
                     IFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            18544..19212
                     /gene="ftsE"
                     /locus_tag="OPY25_000018"
     CDS             18544..19212
                     /gene="ftsE"
                     /locus_tag="OPY25_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCS0925756.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIFFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKARNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRQLVLSDGHLHGG
                     LANE"
     gene            19205..20260
                     /gene="ftsX"
                     /locus_tag="OPY25_000019"
     CDS             19205..20260
                     /gene="ftsX"
                     /locus_tag="OPY25_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HCS0925757.1"
                     /translation="MNRRDAINQIRQFGGRLDRLRKSRGGTGGGRNAPGRQKPTPKPN
                     SRKTNVFNEQVRYAWHGALQDLKSKPLATFLTVMVIAISLTLPSVCYMVYKNVNQAAT
                     QYYPSPQITVYLQKTLDDDAAARVVGQLQAEQGVEKVNYLSREDALGEFRNWSGFGGA
                     LDMLEENPLPAVAVVIPKLDFQSTASLNTLRDRISQINGIDEVRMDDSWFARLAALTG
                     LVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDTINVQKLIGATDGFILRPFLYGGA
                     LLGFSGAFLSLILSEILVMRLSSAVTEVAQVFGTKFDLNGLSFDECLLLLLVCSMIGW
                     IAAWLATVQHLRYFTPD"
     gene            20506..21360
                     /gene="rpoH"
                     /locus_tag="OPY25_000020"
     CDS             20506..21360
                     /gene="rpoH"
                     /locus_tag="OPY25_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HCS0925758.1"
                     /translation="MTKEMQNLALAPVGNLESYIRAANAWPMLSADEERALAERLHYQ
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVSSKDVREMESRMAAQDMTFDMSSDDESDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            21682..22785
                     /gene="livJ"
                     /locus_tag="OPY25_000021"
                     /pseudo
     CDS             21682..22785
                     /gene="livJ"
                     /locus_tag="OPY25_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
     gene            complement(22869..23003)
                     /locus_tag="OPY25_000022"
     CDS             complement(22869..23003)
                     /locus_tag="OPY25_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0925759.1"
                     /translation="MTAGRSAKRKPDGADAYPAYMPGEKIKTTSQFSKNFALQAGGKL
                     "
     gene            complement(22981..23364)
                     /gene="panM"
                     /locus_tag="OPY25_000023"
     CDS             complement(22981..23364)
                     /gene="panM"
                     /locus_tag="OPY25_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HCS0925760.1"
                     /translation="MKLTILRLEHFSAQDQIDLGKIWPEYSASSLSVDETHRIYAARF
                     NERLLGAVRVTLSGTQGALDSLRVREITRRRGVGQYLVEEVIRDNPNVSSWWMADVGV
                     EDRSVMAAFMQALGFTAQHDGWEKR"
     gene            23786..24895
                     /gene="livK"
                     /locus_tag="OPY25_000024"
     CDS             23786..24895
                     /gene="livK"
                     /locus_tag="OPY25_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HCS0925761.1"
                     /translation="MKRKAKTIIAGIVALAVSQGAMADDIKVAIVGAMSGPVAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIQYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQYIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKQGNANIVFFDGITAGEKDFSALIARLQKENID
                     FVYYGGYYPEMGQMLRQARANGLKTQFMGPEGVGNASLSNIAGGAAEGMLVTMPKRYD
                     QDPANKAIVEALKADKKDPSGPYVWITYAAVQSLATAMTRSASHAPLDLVKDLKANGA
                     DTVIGPLKWDEKGDLKGFEFGVFQWHADGSSTVAK"
     gene            24955..25881
                     /gene="livH"
                     /locus_tag="OPY25_000025"
     CDS             24955..25881
                     /gene="livH"
                     /locus_tag="OPY25_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HCS0925762.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMMGIDTSWLLVAAGFIGAIIIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWIVGSSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGVAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            25878..27155
                     /gene="livM"
                     /locus_tag="OPY25_000026"
     CDS             25878..27155
                     /gene="livM"
                     /locus_tag="OPY25_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HCS0925763.1"
                     /translation="MKPMHIAMALFSAAMFFVLAGVFMGVQLELDGTKLVVDTAADIR
                     WQWIFIGTAVVFFFQLLRPMFQKAVKHVSGPKFILPAIDGSTVKQKLFLMALLVIAVA
                     WPFMVSRGSVDIATMTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPLAGLVSAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTLFGLEFSRNTREGGWDTFSNFFGVKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPTRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAVLLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKSGQAKGEQA"
     gene            27152..27919
                     /gene="livG"
                     /locus_tag="OPY25_000027"
     CDS             27152..27919
                     /gene="livG"
                     /locus_tag="OPY25_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HCS0925764.1"
                     /translation="MSQPLLAVNGLMMRFGGLLAVNNVSLELREREIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTITLRERHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPAFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEEIRNNPDVIRAYLGEA"
     gene            27921..28634
                     /gene="livF"
                     /locus_tag="OPY25_000028"
     CDS             27921..28634
                     /gene="livF"
                     /locus_tag="OPY25_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HCS0925765.1"
                     /translation="MEKTMLTFEKVSAHYGKIQALHDVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRASSGRVVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDRFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            28798..29076
                     /locus_tag="OPY25_000029"
     CDS             28798..29076
                     /locus_tag="OPY25_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0925766.1"
                     /translation="MIRSGACIMGTLLFAASFSVNALTSNDFDPRDPAIWQEETATPY
                     PLAATTCEVRHHPDCATWEDEKSDIQRERERRDQRRLQNLYKKYSHRD"
     gene            29308..30624
                     /gene="ugpB"
                     /locus_tag="OPY25_000030"
     CDS             29308..30624
                     /gene="ugpB"
                     /locus_tag="OPY25_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HCS0925767.1"
                     /translation="MISLRHTALGLALSLAFTGQALAVTTIPFWHSMEGELGKEVDSL
                     AQRFNQANPDYKIVPVYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYEVFKDAGINFDESQFVPTVAGYYTDAKSGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQELADYTAKLRAAGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIALLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IRQYAKFNYGVGMMPYDADIKGAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITTAAYELTREQGYYDKNPGADIATRQMLNKPPLPFTKGLRLGN
                     MPQIRTIVDEELESVWTGKKTPQQALDTAVDRGNQLLRRFEKASKS"
     gene            30729..31616
                     /gene="ugpA"
                     /locus_tag="OPY25_000031"
     CDS             30729..31616
                     /gene="ugpA"
                     /locus_tag="OPY25_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HCS0925768.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLVITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLENFVALFHDSYYLDAFWTTIKFSALVTFSGLLVSLFFAALVDYVVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLGEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFRLSLPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATAGGPVQATTTLIYKIYCEGFTGLDLSASAAQSVVLMFL
                     VIILTVVQFRYVESKVRYQ"
     gene            31613..32458
                     /gene="ugpE"
                     /locus_tag="OPY25_000032"
     CDS             31613..32458
                     /gene="ugpE"
                     /locus_tag="OPY25_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HCS0925769.1"
                     /translation="MIENRRGLTIFSHTMLILGIAVILFPLYVAFVAATLDDRAVFET
                     PMTLLPGTQLLENIKTIWVNGVGVNSAPFWLMMLNSFIMAFSITVGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLNSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFRDIVLPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVNLGTAVAGIKGMIATGEGTTQWNQVMAAMLLTLIPPVVIVLAMQRAFVRGL
                     VDSEK"
     gene            32461..33531
                     /locus_tag="OPY25_000033"
     CDS             32461..33531
                     /locus_tag="OPY25_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate import ATP-binding
                     protein UgpC"
                     /protein_id="HCS0925770.1"
                     /translation="MAGLKLQAVTKSWGGKTQVIQPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTSGDIWIDRKRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMSKAHIEERVREAARILELDGLLKRRPRELSGGQRQRVAMGRAIVREPAVFLFDE
                     PLSNLDAKLRVQMRLELQHLHRRLRTTSLYVTHDQVEAMTLAQRVMVMNKGVAEQIGT
                     PVEVYEKPASRFVASFIGSPAMNLLDGVISASGDRFELPGGLALPIGAGYRGHAGRKM
                     TLGIRPEHIALSSQAEGGVPLTVDTLEILGADNLAHGRWGDQKLVVRLAHQQRPAAGS
                     TLWLRLPEHQRHLFDGETGQRV"
     gene            33528..34268
                     /gene="ugpQ"
                     /locus_tag="OPY25_000034"
     CDS             33528..34268
                     /gene="ugpQ"
                     /locus_tag="OPY25_000034"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCS0925771.1"
                     /translation="MSNWPYPHIVAHRGGGKLAPENTLAAIDVGARYGHTMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGGWFSGEFKGEPLPLLSQVAE
                     RCRKHGMMANIEIKPTTGSGRLTGRVVALAARELWAGMTPPLLSSFEIEALEAAQAAV
                     PELPRGLLLDKWREDWRELTTRLGCVSLHLNHKLLDETRVQEIKAAGLRILVYTVNQP
                     QRAAELLRWGVDCICTDRIDDIGPHFQF"
     gene            complement(34265..34636)
                     /locus_tag="OPY25_000035"
     CDS             complement(34265..34636)
                     /locus_tag="OPY25_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HCS0925772.1"
                     /translation="MKRLLLITALLPFAVLAQPINTMNNPNQPGYQIPSQQRMQTQMQ
                     TQARSQQQNLQSQLNANTQRVQQGQPGNGMLGQQTLPNTQGGMLSGSGNPDRMLNHSQ
                     PMLQQDSGTPQPDIPLKTISP"
     gene            34762..36504
                     /gene="ggt"
                     /locus_tag="OPY25_000036"
     CDS             34762..36504
                     /gene="ggt"
                     /locus_tag="OPY25_000036"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HCS0925773.1"
                     /translation="MKPTFMRWVAIAALLAGGTFSAVANPPVAPPVSYGVEEDVFHPV
                     RATQGMVASVDAMATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLLR
                     TKDGATTAIDFREMAPAAATRDMFLDDQGNADAKKSLTSHLASGTPGTVAGFSLALEK
                     YGTMPLNKVVRPAMKLAEEGFVVNDALADDLKTYGSEVIPNHENSKAIFWKDGEPLKK
                     GDKLIQKNLAKSLEMIAENGPAAFYKGAIADQIAGEMQKNGGLMTKEDLASYKAVERT
                     PISGDYRGYQVFSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAY
                     ADRSEYLGDPDFVKVPWQALTNKAYAKTLADQIDINKAKPSSQIKPGKLAPYESNQTT
                     HFSVVDKDGNAVAVTYTLNTTFGTGIVAGNTGILLNNQMDDFSAKPGVPNVYGLVGGD
                     ANAVEPKKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDFGMNVAEA
                     TNAPRFHHQWLPDELRVEKGFSPDTLKLLEQKGQKVALKEAMGSTQSIMVGPDGELYG
                     ASDPRSVDDLTAGY"
     gene            complement(36549..37583)
                     /locus_tag="OPY25_000037"
     CDS             complement(36549..37583)
                     /locus_tag="OPY25_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase"
                     /protein_id="HCS0925774.1"
                     /translation="MKGFLQTVTGPVAHTDMGLTLPHEHLFNDLSSVVDEPHYAFSQQ
                     LVGKKVSADLQWGLKHDPYCCADNMDRKEIDDVIFEINNFMSLGGRTIVDATGSESIG
                     RDASALREVALKTGLNIVASSGPYLEKFESTRIHKPVELLASLIDKELNQGIGETDIR
                     AGMIGEIGVSPAFTQAERNSLRAASLAQCNNPHTAMNIHMPGWLRLGDEVLDIVLEEM
                     NVSPAKVSLAHSDPSGKDVVYQRKMLDRGVWLEFDMIGLDITFPKEGVAPGVQETADA
                     VANLIALGYADQIVLSHDVFLKQMWAKNGGNGWGFVPNVFLAYLAARGVDNDTLRKLC
                     IDNPARLLTA"
     gene            complement(37580..38551)
                     /locus_tag="OPY25_000038"
     CDS             complement(37580..38551)
                     /locus_tag="OPY25_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0925775.1"
                     /translation="MNKNKYSTPLLMLATILAGMLSPMQSAVNGQLGHWLQDGNACAV
                     ISFASGLVVMFFIIIARKETRQQFASIPTLIKKRKIPLWNWFAGLCGAMVVFSEGASA
                     SALGVATFQTALISALLLSGLLCDRFGIGVEEKKYFTPWRITGALFAVIATIFVVSPQ
                     WHSTSFILLAILPFLAGLLAGWQPAGNAKVAEATGSMLVSITWNFIVGFCVLGAALAI
                     RIALGHVTIQLPDTWWMYLGGPLGLLSIGLMAILVRGLGLLMLGVASTAGQLLGSVLI
                     DELIPSLGNTVYLVTIIGTLFALVGAIVTTIPEYRASKMAQKMEVSE"
     gene            complement(38605..39366)
                     /locus_tag="OPY25_000039"
     CDS             complement(38605..39366)
                     /locus_tag="OPY25_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0925776.1"
                     /translation="MNNTQKKLKVLFIGESWHIHMIHSKGYDSFTSSKYEEGATWLLE
                     CLRKGGVDIDYMPAHTVQIAFPESIDELNRYDVIVISDIGSNTFLLQNETFYQLKIKP
                     NALESIKEYVKNGGGLLMIGGYLSFMGIEAKANYKNTVLAEVLPVIMLDGDDRVEKPE
                     GICAEAVSPEHPVVNGFSDYPVFLGYNQVVARDDADVVLTINNDPLLVFGEYQQGKTA
                     CFMSDCSPHWGTQQFMSWPFYTDLWVNTLQFIARK"
     gene            complement(39382..40596)
                     /locus_tag="OPY25_000040"
     CDS             complement(39382..40596)
                     /locus_tag="OPY25_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462448.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCS0925777.1"
                     /translation="MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAG
                     QGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESAQKIKKGLSAMKNNVCVIGSFNV
                     DIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
                     INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKE
                     AIVHSDIVLVQLETNYEALQQTIRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNE
                     TEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAYDGTQFIYSPAFPAV
                     VKNTAGAGDAFNGALSSGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRI
                     QGSHYKQTISTH"
     gene            complement(40861..41349)
                     /gene="yhhY"
                     /locus_tag="OPY25_000041"
     CDS             complement(40861..41349)
                     /gene="yhhY"
                     /locus_tag="OPY25_000041"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCS0925778.1"
                     /translation="MSEIVIRHAEPKDYDAIRQIHAQPEVYHNTLQVPHPSLEMWQAR
                     LTEQAGVKQLVACIDDIVVGHLSIQVTQRPRRSHVADFGICVDARWHNRGIASALIRT
                     MIDMCDNWLRVERIELTVFVDNEPAVAVYKKYGFEIEGTGKKYGLRNGEYVDTYFMAR
                     VK"
     gene            41816..42853
                     /locus_tag="OPY25_000042"
     CDS             41816..42853
                     /locus_tag="OPY25_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCS0925779.1"
                     /translation="MTLHCAFIGFGKSTTRYHLPYVLNRKDTWHVAHIFRRHAKPEEQ
                     APQYSHIHFTSDLDEVLGDPQVKLVIVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AEAKVLFELARSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGKIVEIESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGA
                     LKAIVKTSHLVKIDYPKFIVHGTKGSFVKYGIDQQETSLKANIMPGEPGFAADESVGV
                     LEYVNDEGVTVKEEVKPETGDYGRVYDALYQTLTIGTPNYVKESEVLTNLEILERAFE
                     QATPATITLAK"
     gene            42977..43672
                     /locus_tag="OPY25_000043"
     CDS             42977..43672
                     /locus_tag="OPY25_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HCS0925780.1"
                     /translation="MIYLRKANDRGHANHGWLDSWHTFSFADYYDPNFMGFSALRVIN
                     DDVIDAGQGFGTHPHKDMEILTYVLEGAVEHQDSMGNKEQVPAGEFQIMSAGTGVRHS
                     EYNPSKTDRLRLYQIWIIPQETGITPRYEQRRFDAAQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGTKATTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            44040..45035
                     /gene="gntR"
                     /locus_tag="OPY25_000044"
     CDS             44040..45035
                     /gene="gntR"
                     /locus_tag="OPY25_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HCS0925781.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIEAVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSQSPCLDIAV
                     GFDNFEAARQMTAAIIARGHRHIAYLGARLDERTIIKQKGYEQAMRDAGLVPYSVMME
                     QSSSYSSGIELMRQARREYPQLDGIFCTNDDLAVGAAFECQRLGLKIPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGETVTPKMLDLGFTLSPGGSI"
     gene            45174..45707
                     /gene="gntK"
                     /locus_tag="OPY25_000045"
     CDS             45174..45707
                     /gene="gntK"
                     /locus_tag="OPY25_000045"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCS0925782.1"
                     /translation="MSTTNHDHHVYVLMGVSGSGKSAVASAVAHQLHAAFLDGDFLHP
                     RCNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKISLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADERDVLVVDIDQPL
                     EGVVASTIEVINKGSTL"
     gene            45704..47044
                     /gene="gntU"
                     /locus_tag="OPY25_000046"
     CDS             45704..47044
                     /gene="gntU"
                     /locus_tag="OPY25_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HCS0925783.1"
                     /translation="MSTLTLVLTAVGSVLLLLFLVMKARMHAFVALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAIVVALGAMFGKILHETGAVDQIAVKMLKSFGHNRAH
                     YAIGLAGLICALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLLP
                     GPAPMLLASQMHADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELRIPDDITEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNFSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAQTLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(46967..47341)
                     /locus_tag="OPY25_000047"
                     /pseudo
     CDS             complement(46967..47341)
                     /locus_tag="OPY25_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_452851.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
     gene            47467..48573
                     /gene="asd"
                     /locus_tag="OPY25_000048"
     CDS             47467..48573
                     /gene="asd"
                     /locus_tag="OPY25_000048"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCS0925784.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQFGQAA
                     PTFGDTSTGTLQDAFDLDALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASTL
                     RMKDDAIIILDPVNQDVITDGLNNGVKTFVGGNCTVSLMLMSLGGLFAHNLVDWVSVA
                     TYQAASGGGARHMRELLTQMGQLYGHVADELATPSSAILDIERKVTALTRSGELPVDN
                     FGVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTASVIPVDGLCVRVGALRCHS
                     QAFTIKLKKEVSIPTVEELLAAHNPWAKVVPNDRDITMRELTPAAVTGTLTTPVGRLR
                     KLNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            48949..51135
                     /gene="glgB"
                     /locus_tag="OPY25_000049"
     CDS             48949..51135
                     /gene="glgB"
                     /locus_tag="OPY25_000049"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HCS0925785.1"
                     /translation="MSSRIDRDVINALIAGHFADPFSVLGMHQTQAGLEVRALLPDAT
                     DVWVIEPKTGRKVGKLECLDARGFFCGVLPRRKNFFRYQLAVTWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKFELLDANGNLRIKADPYAFEAQMRPETAS
                     MICGLPEKVTPSEERQKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPVNEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFINAAHAAGLNVIL
                     DWVPGHFPSDEFSLAEFDGTHLYEHSDPREGYHQDWNTLIYNYGRREVSNYLVGNALY
                     WMERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRIIGEQV
                     PGAVSMAEESTDFSGVTRPPETGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLT
                     FGMLYNHTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKALHELDFDAY
                     GFEWLVVDDNERSVLIFVRRDKAGNEIIVASNFTPVPRHDYRFGINQPGRWREILNTD
                     SMHYHGSNTGNGGVVHSDEIESHGRQHSLNLTLPPLATIWLMREGE"
     gene            51132..53096
                     /gene="glgX"
                     /locus_tag="OPY25_000050"
     CDS             51132..53096
                     /gene="glgX"
                     /locus_tag="OPY25_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HCS0925786.1"
                     /translation="MTQLAIGEATPHGATYDGHGVNFTLFSAHAERVELCVFDSRGNE
                     RRYDLPGRRGDVWHGYLAGARPGLRYGYRVHGPWQPAQGHRFNPAKLLLDPYARQVEG
                     ELKDHPLLHGGHDEPDYRDNAAVAPKSVVISDHYDWEDDAAPRTPWGKTVIYEAHVKG
                     LTYLHPELPQEIRGTYKALGHPVMVAYFKQLGITALELLPVAQFASEPRLQRMGLTNY
                     WGYNPMAMFALHPAWASSPETALDEFRDAVKALHRAGIEVILDIVLNHSAELDLDGPT
                     FSLRGIDNRSYYWIRDDGDYHNWTGCGNTLNLSHPGVVEYACECLRYWMETCHVDGFR
                     FDLASVMGRTPTFRQDAPLFAAIKACPVLSTVKLIAEPWDIGEGGYQVGNFPPPFAEW
                     NDHFRDAARRFWLPRNLTTGEFACRFAASSDVFKRNGRAPGASVNLLTAHDGFTLRDC
                     VCFNQKHNEANGEENRDGTNSNYSDNHGKEGLGGPLDLMERRRDSIHALLATLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNALTWLDWQQANRGLTTFTAALIRLRQQIPALTG
                     NSWWEEGDGNVRWLNKNAQPLSADEWQNGPKLMQILLSDRFLIAINATLEVTDIVLPE
                     GEWRAVPPFAGEDNPVITAVWQGLCVFQRG"
     gene            53111..54406
                     /gene="glgC"
                     /locus_tag="OPY25_000051"
     CDS             53111..54406
                     /gene="glgC"
                     /locus_tag="OPY25_000051"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HCS0925787.1"
                     /translation="MVSLEKNDRVMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCLNSGIRRIGVITQYQSHTLVQHIQRGWSLFSEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRCYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIKEATAFGVMAVDENDKIIDFVEKPANPPAMPGDASKSLASMGIYVF
                     DADYLYELLAADDKDDASSHDFGKDIIPKITREGMAYAHPFPLSCVQSDPQAEPYWRD
                     VGTLEAYWKANLDLASVTPELDMYDQNWPIRTHMESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCIISGSVVVQSVLFPRVRINSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACIIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLQVKQER"
     gene            54406..55839
                     /gene="glgA"
                     /locus_tag="OPY25_000052"
     CDS             54406..55839
                     /gene="glgA"
                     /locus_tag="OPY25_000052"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HCS0925788.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDVRVLLPGF
                     PDIRRGIPDAHVVSRRDTFAGKISLLFGHYNGVGIYLIDAPHLYERPGSPYHDTNLYA
                     YIDNVLRFALLGWVGCEMACGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAKHMDDIELPWSFFNMHGLEFNGQLSFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLRQRHLEGRLSGILNGVDEKIWNPESDLLLASRYTRDTLEEKAEN
                     KRQLQIAMGLKVNDKVPLFAVVSRLTNQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEHPGQAGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDSSLENLADGIASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            55859..58306
                     /gene="glgP"
                     /locus_tag="OPY25_000053"
     CDS             55859..58306
                     /gene="glgP"
                     /locus_tag="OPY25_000053"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HCS0925789.1"
                     /translation="MNAPFTYASPTLSVEALKHSIAYKLMFTIGKDPVIANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNALLSLGIYDDVKGAL
                     EAMGLDLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VDGRQKESPDYWLEYGNPWEFKRHNTRYKVLFGGRIQQEGKKARWIETEEILAVAYDQ
                     IIPGYDTDATNTLRLWNAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSATVQDILHRHYQLHKTYENLADKIAIHLNDTHPVLSIPELMRL
                     LIDEHKFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTSLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPTRFCNVTNGVTPRRWLALANPPLSDVLDENIGRTWRTDLSQLSELKQHCD
                     YPLVNHAVRQAKLENKKRLAVVIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKENPEADWVPRVNIFAGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQVIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMQ
                     EHVGEENIFIFGNTAEEVEALRRQGYKPRDYYEKDEELHQVLTQIGNGVFNPEEPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYRRPEEWTTKAMLNIANMGYFSSDR
                     TIKEYAENIWHIDPVRL"
     gene            complement(58398..59906)
                     /gene="glpD"
                     /locus_tag="OPY25_000054"
     CDS             complement(58398..59906)
                     /gene="glpD"
                     /locus_tag="OPY25_000054"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HCS0925790.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGVRFGADSVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATAARRENGLWIVEAEDIDTGKKYVWQARGLVNATGPWVKQFFDEGM
                     HLPSPYGIRLIKGSHIVVPRVHNQKQAYILQNEDKRIVFVIPWMEEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLKVYNAHFQKQLGRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHAMEKLASYYPGIGPAWTKTCVLPGGDID
                     GSREDYAAKLRRRYPFLTESLARHYSRTYGSNTEWILGEATSLLDLGEDFGHEFYEAE
                     LKYLVDHEWVRRTEDAIWRRTKEGMWLTAEQQSRITQWLAAYVEKHQLSLAS"
     gene            60105..60431
                     /gene="glpE"
                     /locus_tag="OPY25_000055"
     CDS             60105..60431
                     /gene="glpE"
                     /locus_tag="OPY25_000055"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HCS0925791.1"
                     /translation="MEQFECITVEEAYQKLHQGAAVLVDIRDPQSYAMGHAPQAFHLT
                     NDTLGAFMREHGFDTAVMVMCYHGNSSKGAAQYLLQQGYDAVYSIDGGFEAWHRRFPA
                     DVANGA"
     gene            60507..61337
                     /gene="glpG"
                     /locus_tag="OPY25_000056"
     CDS             60507..61337
                     /gene="glpG"
                     /locus_tag="OPY25_000056"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HCS0925792.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQ
                     AERVRVELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVML
                     ACVVVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
                     "
     gene            61430..62188
                     /locus_tag="OPY25_000057"
     CDS             61430..62188
                     /locus_tag="OPY25_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HCS0925793.1"
                     /translation="MKQTQRHDAIIELVKKQGYVSTEELVEHFSVSPQTIRRDLNDLA
                     EQNMILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAAQIPNGSTLFIDIGTT
                     PEAVAHTLLGHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATQDFI
                     AQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDTLPPPGVMQVIADHHIQLELC"
     gene            complement(62262..64967)
                     /gene="malT"
                     /locus_tag="OPY25_000058"
     CDS             complement(62262..64967)
                     /gene="malT"
                     /locus_tag="OPY25_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HCS0925794.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLLLVTSPAGYG
                     KTTLVSQWAAGKNELGWYSLDEGDNQQERFASYLIAAIQQATGGHCSTSEAMAQKRQY
                     ASLTSLFAQLFIELAQWHRPLYLVIDDYHLITNPVIHDAMRFFLRHQPENFTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLSSPIEAAESSRMCDDVAGW
                     ATALQLIALSARQNHTSAHHSARRLAGINASHLSDYLVDEVLDNVDVSTRHFLLKSAI
                     LRSMNDALIVRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFSYHPLFGSFLRQRCQW
                     ELAAELPEIHRAAAESWMEQGFPSEAIHHALAAGDAQMLRDILLNHAWGLFNHSELAL
                     LEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGVMDGTLHAE
                     FNALRAQVAINDGNPEEAERLAKLALDELPLAWFYSRIVATSVHGEVLHCKGNLSQSL
                     SLMQQTEQMARHHDVWHYALWSLIQQSEIQFAQGFLQAAWETQERAFQLIKEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIAVLSTFQPQQQLQCLTLLVQCSLARGD
                     LDNARSQLNRLEKLLGNGRYHCDWISNADKVRVIYWQLTGDKKSAANWLRHTPKPAFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     SGRKNDAQRVLLDALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPEMEQHRAQRI
                     LRYINQHHRHKFAHFDEGFVERLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELAVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV"
     gene            65561..67954
                     /gene="malP"
                     /locus_tag="OPY25_000059"
     CDS             65561..67954
                     /gene="malP"
                     /locus_tag="OPY25_000059"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HCS0925795.1"
                     /translation="MSQPTFNKDQFQAALTRQWQRFGLLSASDMTPRQWWQAVSGALA
                     ELLSAQPVAQPTKGQRHVNYISMEFLIGRLTGNNLLNLGWYQDVSDVLKAHDINLTDL
                     LEEEVDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVEGKQMEAPD
                     DWHRGSYPWFRHNEALDVQVGIGGKVTKEGRWKPGFVITGQSWDLPVLGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGAFLRAEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLLDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALECWDERLIKALLPRHMQIIKQINDRFKALVDNTWPGDKQ
                     VWAKLAVVHDRQVRMANMCVVSGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPQLAALLDKTLKKEWANDLDQLINLEKYADDATFRQQYRDIKRANK
                     ERLVKFIQARTGIEISSHAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVAEAINNDPAVGDKLKVVFLPDYCVSAAEMLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     EVKALKAKGYDPVKWRKKDKVLDAVLKELESGQYSDGDKHAFDQMLHSLGKQGGDPYL
                     VMADFAAYVEAQKQVDALYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            67964..70045
                     /gene="malQ"
                     /locus_tag="OPY25_000060"
     CDS             67964..70045
                     /gene="malQ"
                     /locus_tag="OPY25_000060"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HCS0925796.1"
                     /translation="MENKRLDSAALAAGISPSYINAHGKPQSIGAETKRRLLAAMHGT
                     TTGPQAVVPNVKVYTAGKKMALPVEGRGEFAWLLTTEEGEHYKGRVTGGKKLNLPATL
                     PEGYHTLTLTQDEQRTHCRIIVAPPRCYEPQALLEGKKLWGACVQLYTLRSEKNWGIG
                     DFGDLKSMLVDVATRGGAFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVE
                     DFRLSEEAQAWWQMPATQQKLRQARDAQWVDYATVTALKITALRMAWTRFAARDDAQM
                     AEFRHFIAREGESLYWQAAFDALHAYQVKEDGQRWGWPAWPEAYQSVESPAVKQFCEA
                     HREEVEFYLWLQWLAWRQFAACWDTCQSFKLPIGLYRDLAVGVAEGGAETWCDRELYC
                     LKASVGAPPDILGPLGQNWGLPPMDPHIIVARAYEPFIDLLRANMQNCGALRIDHVMS
                     LLRLWWIPYDETADQGAYVHYPVDDLLSILALESQRHRCMVIGEDLGTVPVEIVGKLR
                     DSGVYSYKVLWFENDLEKNFRAPGAYPQQSMAVASTHDLPTLRGYWECGDLTLGKALG
                     LYPDEVILRGLYEDRERAKQGLLDALHKYGCLPKRAGHKALLMSMTPTLNRGLQRYIA
                     DSNSGLLGLQPEDWLDMADPVNVPGTSDQYKNWRRKLSASLEAMFADEGVNKLIKDLD
                     KRRKAAAKKKK"
     gene            complement(70164..71480)
                     /gene="gntT"
                     /locus_tag="OPY25_000061"
     CDS             complement(70164..71480)
                     /gene="gntT"
                     /locus_tag="OPY25_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HCS0925797.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAAAANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFHADMGKTLLFGTILAIPTVILAGPVYARFLKGIDKPIPEGLYSAKTFTEEE
                     MPGFGVSVWTSLVPVILMAMRAVAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNV
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLIGCLLLGMVV"
     gene            complement(71857..72432)
                     /gene="nfuA"
                     /locus_tag="OPY25_000062"
     CDS             complement(71857..72432)
                     /gene="nfuA"
                     /locus_tag="OPY25_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HCS0925798.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            complement(72491..73174)
                     /gene="gntX"
                     /locus_tag="OPY25_000063"
     CDS             complement(72491..73174)
                     /gene="gntX"
                     /locus_tag="OPY25_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HCS0925799.1"
                     /translation="MLTVPGLCWLCRMPLALSHWGICSVCARAVRQRVSLCPQCGLPA
                     GHPSLPCDRCLQKPPPWQRLVSVSDYTPPLSLLVHQLKFTRRSEIAAALARLLLQEVL
                     MARRSTGLPLPDRIVSVPLWSRRHWRRGFNQSDLLCQPLAHWLGCAWDSQTITRVRAT
                     ATQHHLSARLRKRNLKNAFRLELPVQGLHMVIVDDVVTTGSTVAEIAQLLLRNGAATV
                     QVWCLCRTL"
     gene            73212..73982
                     /gene="bioH"
                     /locus_tag="OPY25_000064"
     CDS             73212..73982
                     /gene="bioH"
                     /locus_tag="OPY25_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HCS0925800.1"
                     /translation="MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHL
                     VDLPGYGRSSGFGAMTLEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQAL
                     VTVASSPCFSAREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDART
                     LKSVVLAQPMPDVEVLNGGLEILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIAPLL
                     DTLWPHSTSQIMAKAAHAPFISHPAAFCQALMTLKSSL"
     gene            complement(74018..74944)
                     /locus_tag="OPY25_000065"
     CDS             complement(74018..74944)
                     /locus_tag="OPY25_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCS0925801.1"
                     /translation="MATSTTSTPHDAVFKQFLCHPDTARDFLEIHLPSTLRQICNLNT
                     LRLESGSFIEEDLRPHYSDILWSLETSEGDGYIYVVIEHQSTPDAHMAFRLMRYAMAA
                     MQRHLEAGHKTLPLVVPMLFYHGNRSPYPFSLCWLDEFADPVMARKLYATAFPLVDIT
                     VVPDDEIMRHRRVALLELIQKHIRQRDLMGLVEQLVALLVKGYANDTQLQSLFNYMMH
                     TGDAARFNTFIRQVAMRIPQHKEKIMTIAERLRQEGHRNGLQKGLQQGKQEGQRLAAL
                     RIARSMLNDGFDRDTVLRVTGLAPADLASESH"
     gene            complement(75179..75415)
                     /gene="feoC"
                     /locus_tag="OPY25_000066"
     CDS             complement(75179..75415)
                     /gene="feoC"
                     /locus_tag="OPY25_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HCS0925802.1"
                     /translation="MASLIQVRDLLALRGRMEATQISHTLHAPQPMIDAMLNQLEIMG
                     KAVRIPEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            complement(75428..77746)
                     /gene="feoB"
                     /locus_tag="OPY25_000067"
     CDS             complement(75428..77746)
                     /gene="feoB"
                     /locus_tag="OPY25_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HCS0925803.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQ
                     FATTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQQVRIDVDALSTRLGCPVVPLVSTRGRGIEALK
                     LAIDRHNANDNVELVHYAQPLLREAGFLADAMAQEMPLQQRRWLGLQMLEGDIYSRAY
                     AGEAAQNLDTSLARLKDEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTRAVDK
                     IILNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDAGSVAIFIHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYVLGIVMAVLTGLMLKHTIMRGEASPFVMELPVYHVPHIKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEAFNPADFHLGDELLGAVDDTWQSL
                     KDTFSLSVLANPIEASKGDGEMATGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMSFSILWGLNIAYSLATLFYQVTSFSQHPTYSLICILAVIVFNVVVLS
                     LLRRARSRVDIELLATRKSVTSCCSGTAGNCH"
     gene            complement(77765..77992)
                     /gene="feoA"
                     /locus_tag="OPY25_000068"
     CDS             complement(77765..77992)
                     /gene="feoA"
                     /locus_tag="OPY25_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HCS0925804.1"
                     /translation="MQFTPDTAWKITGFAREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALIEVEAVSC"
     gene            complement(78429..80759)
                     /locus_tag="OPY25_000069"
     CDS             complement(78429..80759)
                     /locus_tag="OPY25_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312276.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCS0925805.1"
                     /translation="MMNDSFCRIIAGEIQANAGQVEAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLGYLRELEDRRQAILKSISEQGKLTDELAGAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWNEPSHDPDVKAAKYIDGDKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVATVVSGKEEEGAKFRDYFDHHEPIANV
                     PSHRALAMFRGRNEGILQLSLNADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDGTGKLVATDTIYPHTGQAAKAATVIAALCEKYHVELVAIGNGTASR
                     ETERFYLDVQKQFPNVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSNELRHLKAADFTDDKFGVPTVSDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLLPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSTKFVDDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETAARRGGGADRAQ
                     GNRPASKAAKPRGRDAQPAGNSAMMDALAAAMGKKR"
     gene            complement(80858..81331)
                     /gene="greB"
                     /locus_tag="OPY25_000070"
     CDS             complement(80858..81331)
                     /gene="greB"
                     /locus_tag="OPY25_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015703675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HCS0925806.1"
                     /translation="MKTPLITREGYETLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGDTLK
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPVGEANWYVNAIEYVK"
     gene            81557..82276
                     /gene="ompR"
                     /locus_tag="OPY25_000071"
     CDS             81557..82276
                     /gene="ompR"
                     /locus_tag="OPY25_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HCS0925807.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            82273..83625
                     /gene="envZ"
                     /locus_tag="OPY25_000072"
     CDS             82273..83625
                     /gene="envZ"
                     /locus_tag="OPY25_000072"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HCS0925808.1"
                     /translation="MRRMRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYTNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMGEEDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNSVLGEVIAAESGYEREINTALQAGSIQVKMHP
                     LSIKRAVANMVVNAARYGNCWIKVSSGTESHRAWFQVEDDGPGIKPEQRKHLFQPFVR
                     GDSARSTSGTGLGLAIVQRIIDNHNGMLEIGTSERGGLSIRAWLPVPVARVQGTTKEA
                     "
     gene            complement(83700..85319)
                     /gene="pckA"
                     /locus_tag="OPY25_000073"
     CDS             complement(83700..85319)
                     /gene="pckA"
                     /locus_tag="OPY25_000073"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462403.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCS0925809.1"
                     /translation="MRVNNLTPQDLKAYGINDVQDIVYNPSYDTLYQEELNPGLEGYE
                     RGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTLWWSDKGKGKNDNKPLSQETWQ
                     HLKGLVTHQLSGKRLFIVDAFCGANADTRLSVRFITEVAWQAHFVKNMFIRPTDEELV
                     GFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMFSVM
                     NYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDG
                     VFNFEGGCYAKTIKLSKEAEPEIYHAIRRDALLENVTVREDGTVDFDDGSKTENTRVS
                     YPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTANQTQYHFLSGFTAKLAG
                     TERGVTEPTPTFSACFGAAFLTLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRIS
                     IKDTRAIIDAILNGSLDNAETFRLPLFDLAIPTELPGVDTHILDPRNTYASPEQWQEK
                     ATALAKLFIENFEKYTDTPAGEALVSAGPKL"
     gene            85699..87408
                     /locus_tag="OPY25_000074"
     CDS             85699..87408
                     /locus_tag="OPY25_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HCS0925810.1"
                     /translation="MESVALSRTTRWGMLLTGLLQGVLCYLLMAWLVPQNSDWLFYGM
                     PATIALSSMLLLTVVSFKQRALWGWLGLIFVVVLAMSGWLKWQVEAVEKWRLAELLWL
                     YGLRLVLMAMLVLPWMQYQLHSQTGSARYPQFYLRLWHNVLTLFIVLVANGLFWLVLL
                     LWSALFRLVGIRFFSTLFFETEAFIYVTIGLITALAVILARTQSRLVAAVQKLLTLIA
                     TGLLPVVSLLALLFIVTLPFTGLEAISARVSATGLLSTLTLMLLLLVAIVNEPQKRVL
                     PYPRVLRGMISASLCVAPIYMLLAGWALWVRIQQYGWTPDRLYGALTASVLLVWSFGY
                     LIGLLRRGRDPDEWQGKVILSVSLLTLVILLLLASPVLDVWRISVNSHMARYHSGKIT
                     ADQISLYMLDHSGKPGQEALKSLRDDEAFTQNRKRNRELMTFLQRNKVPPTADDLARV
                     VMIAPGSQKPDAAFWAFVKEQSYSDASCLEPDACVLVSQDLNGDGQPEQVLYNFIVAE
                     SQVYGLKEGKWTQKAFARLPDGFSKTQLLHAIAGHRLDSAPKAWRDIIVDGQRLDVDY
                     YNE"
     gene            complement(87519..88397)
                     /gene="hslO"
                     /locus_tag="OPY25_000075"
     CDS             complement(87519..88397)
                     /gene="hslO"
                     /locus_tag="OPY25_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCS0925811.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILDNHNYPQSVKTV
                     LAELLVATSLLTATLKFAGDITVQLQGDGPLSLAVINGNNQQQMRGVARVQGDIPDNA
                     DLKTLVGNGYLVITITPEEGERYQGVVGLEGDTLAACLEDYFLRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQAEDFDHLAMLTETIKSEELLTLPANDVLWRLYHEEEV
                     TLYDPQEVEFKCTCSRERCAGALKTLPDEEVDSILAEEGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(88422..88823)
                     /gene="hslR"
                     /locus_tag="OPY25_000076"
     CDS             complement(88422..88823)
                     /gene="hslR"
                     /locus_tag="OPY25_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HCS0925812.1"
                     /translation="MKEKSSVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAVALYEETAESVEKREKMAQAR
                     KLNALTMPHPARRPDKKERRDLLRFKHGDSE"
     gene            complement(88834..89502)
                     /gene="yrfG"
                     /locus_tag="OPY25_000077"
     CDS             complement(88834..89502)
                     /gene="yrfG"
                     /locus_tag="OPY25_000077"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006893127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HCS0925813.1"
                     /translation="MHIDIDWQNVDTVLLDMDGTLLDLAFDNYFWQKLVPETYGAQQG
                     ISPQDAQEYIRQQYHAVQHTLNWYCLDYWSERLGLDICAMTTAQGPRAVLRDDTVPFL
                     NALKASGKRRILLTNAHPHNLAVKLEHTGLASHLDLLLSTHTFGYPKEDQRLWRAVTE
                     ETGISAEKTLFIDDSEPILDAAARFGIRYCLGVTNPDSGLAEKHYTRHPSLNDYRRLI
                     PSLK"
     gene            complement(89567..91699)
                     /gene="igaA"
                     /locus_tag="OPY25_000078"
     CDS             complement(89567..91699)
                     /gene="igaA"
                     /locus_tag="OPY25_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HCS0925814.1"
                     /translation="MSTILIFIAALLACSLLAIWRFRVKSRRGSLPWFSAFQDAQTRK
                     LLPEERSAVENYLDNLSQIQQVPGPTGASAAPISLTLNAESNSVVILTHSITRYGITT
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENNVELILTDTLPLVISLNGHTLQEYMQESR
                     GYALQNTASTQASIRGEESEQIELLNIRQETHEEYALSRPAGLREALLIVASFLLFFF
                     CLITPDVFVPWMIGGAILLLAAGLWGLFAPPSKSALREIHCLRGTPRRWGLFGENNQE
                     QINNISLGIIDLIYPAHWQPYITQDLGQQTDIDIYLDRHVARQGRFLSLHDEVKNFPL
                     QHWLRSTVIAIGSLLVLFMLLFWIPLDMPIKFTLSWMKGAQTIEATTVKQLEKAGVRV
                     GDTLHLSGKGMCNIHSGATWSGQSNSPFMPFDCSQIIWNDAPALPLPESDLVNKAMAL
                     SQAVNRQLHPKPEDDSRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCAAEDECVRLK
                     NALVNLGNSKDWNALVKRANAGKLDGVNVLLRPVSAESLENLVTTSTAPFISRETARA
                     AQSLNSPAPGGFLIASDEGSELVDQAWPSTPLYDYPAQEQWSAFQRLAQTLMQTPFSA
                     EGIVTSVYTDANGTQHISLHRIPDKSGWWRYLGTTLLMLAMIVSAVYNGIQAFRRYQR
                     HRTRMADIQEYYESCLNPRLTVSPENLI"
     gene            92022..92585
                     /gene="nudE"
                     /locus_tag="OPY25_000079"
     CDS             92022..92585
                     /gene="nudE"
                     /locus_tag="OPY25_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000045725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HCS0925815.1"
                     /translation="MSKSLQKPTILKVETVAQSRLFNVESVDLEFSNGVRRVYERMRP
                     STREAVMIVPIVDEHLILIREYAVGTESYELGFSKGLIDPGETVFEAANRELKEEVGF
                     GAHNLTFLKKLSMAPSYFSSKMNIVVAEDLYPESLEGDEPEPLPQVRWPLAHLMDLLE
                     DPDFNEARNVSALFLVREWLKAQGRIA"
     gene            complement(92681..95233)
                     /gene="mrcA"
                     /locus_tag="OPY25_000080"
     CDS             complement(92681..95233)
                     /gene="mrcA"
                     /locus_tag="OPY25_000080"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HCS0925816.1"
                     /translation="MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQVYSADGELIAQYGEKRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLSEGYITQAQYDQARSEPIDANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYSGPANVLWKVGETAWDSK
                     KITDTLKALPTYGPLLPAVVTSANPQEATAALADGTSVSLHMEGMRWARPYRSDTQQG
                     PTPRKVTDVVQTGQQIWVRQVDNDWWLAQVPEVNSALVSLNPQTGAVLALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWRPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVIFEAKPKIACTECDIPVIYGNT
                     QKSDVLENTNVEEVAVSQEQQNSAVPMPELEQANQALVAQNGTQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWMGTGWRAARDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLASGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF"
     gene            95354..96133
                     /locus_tag="OPY25_000081"
     CDS             95354..96133
                     /locus_tag="OPY25_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HCS0925817.1"
                     /translation="MAFKTWQIGLHIQQHEALAIAVIRGASGWSLQRWWRLPLMNAST
                     AEGTIPDPQSLAHVLRPWSRELPLRHRIYLSFPANRTLQRAFPHPPMRLREREQVAWL
                     SQTMARELDMDPDLLRFDFQDDALSPAFNVTAVQSKEISELLTLAQTLNVRIAAVTPD
                     ACALQRLLPFIPSGRQCLVWRDESQWLWATRYAWGRKSAREAMTLHDLAATLSVVPEH
                     ISLCAEGEFDPWRAVTVRQPPVPPDGYRFAIALGLAMGEIR"
     gene            96133..96672
                     /locus_tag="OPY25_000082"
     CDS             96133..96672
                     /locus_tag="OPY25_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HCS0925818.1"
                     /translation="MAHSVNLLPWRRQHYVARLRLWCVVWGASLLLIASLATIARLVF
                     WQEGRINELLLTAENGRTTALAANIPQLQQRQRQQQARLQRQAQRELTQAWQSILTDL
                     ANLLPEQAWLTSLNYQQETLELEGLARTFDALLTLETSLRHYVSFPLNRTGATRQDAQ
                     GRWQFHYQLTRSAARERAL"
     gene            96656..97129
                     /locus_tag="OPY25_000083"
     CDS             96656..97129
                     /locus_tag="OPY25_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0925819.1"
                     /translation="MNALFDIWYGMSRRGRVFCWCAGVLCLTLTVALSVGYPGWKTLD
                     TQHARLSQQREAARQQWRHLRRLSVAAEPLFGRTIENPRPFSPLDFQAPPLRLLHWQP
                     SAQGGEMALKTSWDAVPSLFVRLAESEMSVSRFSLRREGAELLITLQLERLANEG"
     gene            97119..97520
                     /locus_tag="OPY25_000084"
     CDS             97119..97520
                     /locus_tag="OPY25_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2531 family protein"
                     /protein_id="HCS0925820.1"
                     /translation="MKVSRGVLLCFCLLTLTGMRDPFRPPEDRCRIAELSQWRYQGAV
                     RKGERWTGILKDSQQKWRRVEEGQTLENGWTIVRLTAEALTLTTGKNCAPPQWRWLRQ
                     GADNEAMDSHNTDSLDARRAGGKSGESDAGG"
     gene            97435..98673
                     /gene="hofQ"
                     /locus_tag="OPY25_000085"
     CDS             97435..98673
                     /gene="hofQ"
                     /locus_tag="OPY25_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HCS0925821.1"
                     /translation="MKRWIAIILIVLMPAAQAGKAAKVTLVVDDVPVVQVLQALAEQE
                     RQNLVVSPDVSGTLSLHLTDVPWKQALQTVVNSAGLVLRQEGNILHVHSQAWQKEHSA
                     RQDAERLRLQANLPLENRSISLQYADAGELAKAGEKLLSAKGTIMVDKRTNRLLLRDN
                     RAALAELEKWVSQMDLPVAQVELAAHIVTINEKSLRELGVKWTLADATQAGAVGDVTT
                     LSSDLSVAAATSRVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFSRKNKSGSDSVPLLGDIPWLGQLFRHDG
                     KEDERRELVVFITPRLVATE"
     gene            99138..99659
                     /gene="aroK"
                     /locus_tag="OPY25_000086"
     CDS             99138..99659
                     /gene="aroK"
                     /locus_tag="OPY25_000086"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HCS0925822.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDVEGEDGFRNREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLQVEAPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            99716..100804
                     /gene="aroB"
                     /locus_tag="OPY25_000087"
     CDS             99716..100804
                     /gene="aroB"
                     /locus_tag="OPY25_000087"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCS0925823.1"
                     /translation="MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNET
                     LAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVAL
                     GGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAA
                     RASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVL
                     PLTIGKSEVRGGVSHEVVLSAIADCQQA"
     gene            100902..102179
                     /gene="damX"
                     /locus_tag="OPY25_000088"
     CDS             100902..102179
                     /gene="damX"
                     /locus_tag="OPY25_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HCS0925824.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERDNEPQINFDDVDLDAD
                     DRRPTRTRKARSEEPEVEEEYESDEDDTVDEERVERRPRKRKKAAHKPASRQYMMMGV
                     GVLVLLLLIIGIGSALKAPSTSSSEPSASGEKSIDLSGNAADQANATQPAPGATSAEQ
                     TAGNTSQDISLPPISSTPMQGQSPVVADGQQRVEVQGDLNNALTQNPEQMNNVAVNST
                     LPTEPATVAPVRNGSTTRQAAVSEPAERHTTRPERKQAVIELKKPQTTAKTTTAEPKK
                     PVAPVKRTEPAAPAATPKATTTTAAPQATASAAPVQTAKPAQASTTPVAGGGKSAGNV
                     GALKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVTGMYAS
                     KEDAKRAVSTLPADVQAKNPWAKPLHQVQADLK"
     gene            102360..103196
                     /gene="dam"
                     /locus_tag="OPY25_000089"
     CDS             102360..103196
                     /gene="dam"
                     /locus_tag="OPY25_000089"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HCS0925825.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKLRTDEYVQASRELFMPETNQAEVYYQLREEFNTCQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKRPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADKSSVVYCDPPYAPLSATANFTAYHTNSFSLTQQAHLAEIAENLVS
                     NRIPVLISNHDTALTREWYQLAKLHVVKVRRSISSNGGTRKKVDELLALYQPGVATPA
                     RK"
     gene            103214..103891
                     /gene="rpe"
                     /locus_tag="OPY25_000090"
     CDS             103214..103891
                     /gene="rpe"
                     /locus_tag="OPY25_000090"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCS0925826.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGSMVLKSLRQYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKEHGCKAGLVFNPATSLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSE
                     LAKVSHE"
     gene            103884..104642
                     /gene="gph"
                     /locus_tag="OPY25_000091"
     CDS             103884..104642
                     /gene="gph"
                     /locus_tag="OPY25_000091"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HCS0925827.1"
                     /translation="MNKLQNIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWASQERATLRKTMGKPPVDEDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALHASGLSLGLVTNKPTPFVAPLLESLDIAKYFSVVIGG
                     DDVQNKKPHPEPLLLVASRLGMTPEQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     VIALSEPDVIYDSFNDLLPALGLPHSDNQEIKND"
     gene            104635..105639
                     /gene="trpS"
                     /locus_tag="OPY25_000092"
     CDS             104635..105639
                     /gene="trpS"
                     /locus_tag="OPY25_000092"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCS0925828.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQQLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNGLYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVKEKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VAEAVSGMLSELQERYHRFRNDEAFLQKVMKDGAEKASARAAETLKAVYEAIGFVAKP
                     "
     gene            complement(105783..105953)
                     /locus_tag="OPY25_000093"
     CDS             complement(105783..105953)
                     /locus_tag="OPY25_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HCS0925829.1"
                     /translation="MFKFVKIAVVAGVLATLTACTGHIENKKNNCSYDYLLHPAISIS
                     KIIGGCGPAADQ"
     gene            complement(106147..111746)
                     /locus_tag="OPY25_000094"
                     /pseudo
     CDS             complement(106147..111746)
                     /locus_tag="OPY25_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001169948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin BigA"
BASE COUNT        24943 a        29056 c        31796 g        26186 t
ORIGIN      
        1 gctgaatagg gcggagaata ggggcaggaa agtggataaa atattatcgt gttttacctc
       61 cggcaggagc gtttccttat tagaagtacg aatatttgat gccgtgggct gtatccatgt
      121 tttttagccg ggcccggcga cttgagcagg ggtaatcacg catgctttcg ttaccagccc
      181 cttcggtaaa tagattgacg ggcatgattt tttgtctgca acatctgtgc tacaaccgaa
      241 tagacatatt gaatccaggt gttagtattc aatagacagc agttatgagt atgcgtgttt
      301 catttccggc caggaacgct gatgatgaca acattactac ccggtttcac agcattttcg
      361 tcattcactt ccttcgcggc gcgcgttgcc ttaacgctcg ctcaatggcc attgtttttc
      421 attccttctt atcccggatg gaaacccccg ctgagcgcac gcccggcgga ctttgtgaca
      481 cgcatggtta ggcaacaggg attacggcgg gtcgattatg gacaaaatga agcgtcatct
      541 ggtgtggtgg ggagcgggga ttcttgtggc ggtggccgcg atcgcctggt ggatgctgcg
      601 ccctgcggga ataccggagg ggtttgccgc cagcaatggc agaattgaag ccaccgaagt
      661 ggatattgcc actaagattg ccgggcgtat tgataccatc ctcgtttcgg aagggcagtt
      721 cgttcgtcag ggcgaggtgc tggcgaaaat ggatacccgc gtattgcagg agcagcggct
      781 ggaggcgatt gcgcagatta aagaggccga gagcgcagtt gccgccgccc gtgccttgct
      841 ggagcaacgc cagagtgaaa tgcgcgccgc gcagtcggtc gtcaaacagc gggaagctga
      901 gctggactcc gtctctaaac gtcacgtgcg ttctcgttcg ctgtcgcagc gtggcgcggt
      961 atctgtacaa cagttagatg acgatcgcgc ggcggcggaa agcgcgcgcg ccgccctgga
     1021 gaccgccaaa gcgcaggtat ctgcggcaaa agcggcgatt gaggcggcgc gtaccagtat
     1081 tatccaggcg caaacgcgcg tggaagcggc gcaggcgacc gagcggcgta ttgtcgccga
     1141 catcgacgac agcgaattaa aagcgccgcg cgatggacgt gtgcagtacc gcgttgcgga
     1201 gccgggcgaa gtgttatcgg ctggcggccg ggtgttgaac atggtcgatc tcagcgatgt
     1261 ttatatgaca tttttcctgc cgaccgaaca ggcggggttg ttgaagatcg gcggcgacgc
     1321 gcgactggtg ctggacgccg cgccggatct gcgtattccg gcgaccatca gttttgtcgc
     1381 cagcgtggcg cagttcacac ccaaaaccgt ggaaacccac gatgaacggc tgaagctgat
     1441 gttccgcgtc aaagcgcgta ttccgccaga gctgctgcga cagcatctgg aatatgtcaa
     1501 aaccggtttg ccgggaatgg cctgggttcg tctggatgag cgcgtgccct ggcctgacga
     1561 tctgaacgtg aggttgtcgc aatgacgtcg ctgacgctgg tgcctgttcc tcccgtggcg
     1621 cagcttgagg gggtgagcca gcattacgga aaaacggtcg cgctgaacaa tatcacgctg
     1681 gacattcccg cccgtagtat ggtcgggctg attggtccgg acggggtggg taagtcgagc
     1741 ctgctgtcgc tgatttctgg cgcgcgggtg attgagcaag ggaacgttat cgtcctgggc
     1801 ggcgatatgc gcgatgcgaa acatcgccgc gacgtctgtc cgcgcatcgc ctggatgccg
     1861 caggggctgg ggaaaaacct ttatcacacg ctatcggttt atgagaacgt cgattttttc
     1921 gctcgtctct ttggtcatga caaagctgaa cgcgaagcgc gtattaccga gctgctgaac
     1981 agcaccggcc tggcgccgtt tcgtgatcgt cctgccggga agctgtccgg tgggatgaaa
     2041 caaaagctgg ggctgtgctg tgcgctgatt catgacccgg aattactgat tcttgatgag
     2101 cctaccaccg gcgtggactc gctctcccgc gctcagttct gggacttaat cgacagtatc
     2161 cgccaacggc agaccaatat gagcgtgttg gtcgcaacgg cctatatgga agaggcggag
     2221 cgttttgact ggctggtggc gatgaatgcg ggcgagatac tggcaaccgg cagcgcgcag
     2281 caactgcggg caaaaaccca tagcgcgacg ctggagcagg cgtttatcgc cctgttgcca
     2341 gaagcgcagc gccaggcgca taagccagtg gtgatcccgc cgtatcacgc tgagcaggaa
     2401 gagattgcca ttgaggcgaa agatctgacc atgcgcttcg gtaagttcgt cgcggttgac
     2461 catgttaatt tccgcattcc gcgcggcgag atttttggct tcctcggttc aaacggctgc
     2521 ggcaaatcga ccaccatgaa aatgctgacc ggtctgcttc ccgccagcga aggccaagcc
     2581 tggctatttg gccagccggt agacccgaac gacatcgata cccgtcgccg ggtcgggtat
     2641 atgtcgcagg ctttttcgct ctataacgaa ctcaccgtgc ggcagaatct ggaacttcat
     2701 gcccgcctgt ttcatattcc gccagcggag atcccggcgc gcgttgcgca gatgatcgaa
     2761 cgctttatgc taacggaggt ggaagatacg ctccccgctt cgttgccgct cggtatccgc
     2821 cagcgtttat cgttggcggt agcggtgatc catcgcccgg aaatgctgat tcttgatgag
     2881 ccaacgtccg gcgttgatcc ggtcgccagg gatatgttct ggcagcttat ggtcgatctt
     2941 tcgcgtcagg ataaagtgac gatttttatc tcgacccatt ttatgaacga agcggaacgt
     3001 tgcgaccgaa tgtcattgat gcacgccggt aaagtgctcg ccagcggtac gccgcaggaa
     3061 ttggtgcaac agcggggcgc ggccaatctg gaagcggcgt ttatttcctg gctacaggaa
     3121 gctgcgggag cggcgcctga aaccccaata ccgccatccc agacgcccgc cgcgtcagat
     3181 aaaccgtcgc ggcagggatt gagcttccgg cgtttgttca gctacagtcg ccgcgaagcg
     3241 ctggagctac gccgcgatcc ggtacgctcg acgctggcgc tgctgggaac ggtaattctg
     3301 atgctgatta tgggctatgg catcagtatg gacgtggaga acctgcgttt tgccgtactc
     3361 gaccgcgatc aaaccgtcag cagccaggca tggtcgctca atctggcggg atcgcgctat
     3421 tttatcgaac agccgccgct cgccagctat gacgagcttg accggcggat gcgttcggga
     3481 gagttggcgg ttgccattga gatcccgcct aattttggcc gcgatattgc tcgcggtacg
     3541 ccagcgcaga ttggcgtctg ggtggatggc gccatgccca gccgcgccga gacggtgaag
     3601 gggtacgttc aggcgatgca ccaaagctgg ctgcaggagg cggcaagtcg tcagccgaac
     3661 ccggttaaac aaaccgggct gctcaacatt gaaacgcgct atcgctataa cccggatgtg
     3721 aaaagtctgc ccgctatcgt tccggcggtc attccgctgc tgctcatgat gatcccgtca
     3781 atgcttagcg ccctgagcgt ggtgcgggag aaagagctgg ggccgatgat taatctgtac
     3841 gtaacgccga cgacgcgcag tgaatttttg ctgggtaaac aactgccgta tatcgcgctg
     3901 ggtatgctga acttcttgct actgtgcgcg ctgtcggtct ttgtgttcgg cgtgccgctg
     3961 aaaggcagct ttctcacgct taccctcgcg gcgctgcttt acgtcatcat cgccaccggt
     4021 ctggggctgc tgatctccac gtttatgaag agccaaatcg ccgctatttt tgggacgtcg
     4081 attattaccc tcattccggc aacacaattt tccggcatga tcgatccggt ggcttcgctg
     4141 gaaggaccgg gaagatggat cggcgagatc tacccgacca gccattttct gacgatcgcg
     4201 cgcgggacgt tttccaaagc gttggatctg tccgatctct ggtcgttatt tatgccgtta
     4261 ctgattgccg tcccggtggt gatgggtctg agcattctgc tgctgaaaaa acaggagggg
     4321 taatgcgcgg attacgtaat atttataacc tcggcgtcaa agaactgcgc agtctgctgg
     4381 gcgacaaagc gatgctggcg ctgatcgtct tcgcctttac gatttcggtt tactcctccg
     4441 cgaccgtcct gcccggttcg ttgcatcttg cccctatcgc catcgccgat atggatcagt
     4501 cacagttgtc gaaccgtatt gtgaatagtt tttaccgccc gtggtttctg ccgccggaga
     4561 tgattacggc aacggaaatg gatgccggac tggatgccgg acgctatacc tttgcggtca
     4621 atattccgcc gaatttccag cgtgatgtgc tggccggacg tcagcctgat atccaggtta
     4681 acgtcgatgc gacgcgcatg agccaggcgt ttaccggcaa cagttatatc cagaatatta
     4741 ttagcggcga ggtcaacagc tttgtggcgc gcgcggggag atagcgttca gccggtgtcg
     4801 ctggaaattc ggatgcgctt taacccgaat ctggacccgg cgtggtttgg cggcgtgatg
     4861 gcgattatca acaacattac catgctggcg atagtgctga ccggatcggc gctgatccgc
     4921 gagcgagaac atggcacggt agagcatctg ttagtgatgc cggtcacgcc ctttgagatc
     4981 atgatggcaa aagtgtggtc gatggggctg gtcgtgctgg tggtttccgg tttgtctttg
     5041 atgctgatgg tgaaaggcgt acttggcgta ccgattgaag gatcgatccc attgtttatg
     5101 ttgggcgtgg cgctgagcct gttcgccacc acttcaattg ggatttttat gggcaccatc
     5161 gcccgttcga tgccgcagct ggggttatta atgattctgg tgctgttgcc gctacaaatg
     5221 ctctccggcg gttccacgcc gcgcgaaagt atgccgcagg cggtgcagga tattatgctg
     5281 accatgccaa cgacgcattt tgtcagcctt gcccaggcta ttctttatcg cggcgcaggt
     5341 ttaagtattg tctggccgca gttcctgacc ctgctggcga taggcggcgt gttcttcctg
     5401 atagcgctgt tacgcttcag aaaaacgatt ggcacgatgg cgcaaacatt attgccggat
     5461 ggcggctgcg cctcatccgg cctacaaacg acgacgtgcg aacgtaggcc gggcaagcga
     5521 agcgcccccg gcaaggcgct ggggcgttag tcttctttcg gcaaacattg caagtggccg
     5581 tggcgcacgc cgcgctgggc gataacatca tcggcaaaat gctgtacgtc gcccatatcg
     5641 cccttcagaa cggcgatctc cagacagtca tcgtggttga tatggacgtg cagcgtggcg
     5701 acggataaat catgatgatg atgctgggtg gagacgatgc ggctggctaa atcccgtttc
     5761 tcatgttcat aaacatatga aagtaccgcg aaaccctgtg taccgtgttc ctgggtggcc
     5821 tcctgcgcca gagcgccgcg cagaatatca cggatcgctt cggagcgatt gttatagccg
     5881 cgtcgctggc tcaggctgtc cagcgtttcc agtaaatcgt catcgagggt gatggtgaca
     5941 cgttgcatct gacttaaacc ttttggtatg gcgcgtcggc gcatgggaag ctccgcattt
     6001 tgtaacacac gtccgccgcc agagggaaaa ttaatgtgtc ataacgcttt tgttatcgtc
     6061 tgcggcgtca gcgtaaacgg tgtgggggta cagactgcca gactgagcgt atcgagctga
     6121 cactggctga ccgacaaggc agagggcaac gtgctgtcca cgctgacgat ttgccaggcg
     6181 ctgccgccgc gttgttttac gatggcttct ttacgcgtcc agatacgcca gaaggccgcc
     6241 agttgtcgct ccggacgttc cgcttccatt tcagcatgtt cgccgaggct gaataccgca
     6301 tttgccagcg aacgccagtt atcgcgcggg cggatcactt caatatcgca gccgacttca
     6361 ccttcgtcgc taagcaacag agcaatagtg tcgccgctat ggctgaggtt aaaccacagc
     6421 ggcgttccgg cggaaaaagc cggtttaccc tgttcgccat acaccatctc cggtagcggc
     6481 gagagcgcac gggaaagcag cacgcgcccg gccagccagc ttgcccggcg aacgccctgc
     6541 ggcgcctgag cgattaacgc gtcgggcaat tgacctgcgc ttaatgttga cacttttccc
     6601 agaacgatct ggtacatatc aggaccaacg ttgcctatga agaagaggag attgtagcat
     6661 ctgtcgcctc atcccggtaa acggcttttc ggtcggcctg gccccagtaa gatcgccagt
     6721 ttgctgccgc ctttagtggt ttccatccag attttgcaga cgctggtcaa aggaacggac
     6781 aagagcatcc cgaccgggcc taatagccat ccccagacca gtaacgaaag aaataccacc
     6841 agcgtggaca tccccagacg atggcccatc atgcgtggct ccataatgtt gccaatcacc
     6901 atatgaacca ccaaaaagag cgcgccgacc agtacgcatt cgtaaaagcc gttaaataac
     6961 aacgcctgaa tcatgggggg aacggcggaa atcaccgagc cgatattagg aacgtaattg
     7021 agcaaaaagg ccagtacgcc ccacattagc gcaaactgaa tatccattaa tgccagcccc
     7081 agccagataa tcgcgcccgt ccatagactg agcagcgttt tcagcgccag ataatgcgag
     7141 acgcctttca gggcgcggtg caggccggca atatggattt gtggattgtt aagcgcgaaa
     7201 cgtaatttat aaggcacgtg acgcacctca aacagcataa aaaccacggt catcaccagc
     7261 agcacaatgc ttgccatcgc gcccgatacg ccggtcatta atgttgtggt gaagagcatg
     7321 attttatcgg aatccatccc acggagcata cgttccggcg acatatgtaa attcaggaag
     7381 ggcattaact cctgaagatg taaaacctta cgcgtcagct ccttgctgta tttaggcagc
     7441 atagcgataa attcattaag cgatgcggca agcacaccca ccagcgcggt aagcacgatc
     7501 agcatgacga ccaccacgat agtaatcgcc agcggtcgct tcacgccccg gcgaataaac
     7561 caggtcacta atggattaag aacgatggcg aaaaagagcg ccagtaagag ttgtacaata
     7621 atatccgccg cggcatgaat cccggcgaga ataataacca gggaggccag tttcagcaga
     7681 atatgcatac ccgttttgtc gggttgagcg gttgccatga agttttcctt gttgtgtttt
     7741 tttctaagtg tagcggctgc cctgataccg ataatctgaa tctcactact gattttcacc
     7801 gcgcgccatg atagaaaaga aaacatgttg taaaaatgcg gtgatactca tgcccgaacc
     7861 cgtcgctgaa ccggcgctaa acggattgcg cctcaatctg cgtattgtct ccatcgtgat
     7921 gtttaacttt gccagctacc tgactatcgg cctgccgctc gccgtcttgc ccggctatgt
     7981 gcatgatgcg atgggattca gcgcgttctg ggcggggctt attatcagcc tgcaatactt
     8041 cgccactctg ttaagccgtc cccatgccgg gcggtatgcg gatgtattag ggccgaaaaa
     8101 aatcgttgtc tttggcttat gcggctgttt tttaagcgga ctcggctacc tgctggcgga
     8161 tatcgccagc gcctggccga tgatcaattt gttgctactg gggctgggtc gcgtgatttt
     8221 ggggattggg caaagttttg ccggcaccgg ttcgacactg tggggcgtcg gcgtcgtcgg
     8281 gtcgttgcat attggtcggg ttatctcctg gaacggtatc gtcacctacg gcgcaatggc
     8341 gatgggcgcg ccgctgggcg tgctgtgtta tgcctggggc gggttacagg gactggcgct
     8401 aacggtgatg ggcgtggcgc tgttggcggt actgttagcc cttccacgtc cgtcggtgaa
     8461 ggcgaacaaa ggcaagccgc tgccgtttcg cgcggtgctg gggcgtgtct ggctgtatgg
     8521 tatggcgttg gcgctggcct cggcagggtt tggcgtcatc gcgacgttta ttaccttatt
     8581 ttatgatgct aaaggttggg atggcgccgc ctttgcgctc acgttattta gcgtcgcgtt
     8641 tgtcggcacg cgtttgctgt tccctaacgg tatcaatcgc ttaggcgggt tgaatgtcgc
     8701 catgatctgc tttggcgtgg agattattgg tctgttactg gtggggacgg cagccatgcc
     8761 gtggatggca aaaatcggcg ttttactcac ggggatgggg ttttcgctgg tctttccggc
     8821 gctgggtgtg gtggccgtca aagccgtgcc gccgcagaac cagggcgcgg cgctggcgac
     8881 ctataccgtc tttatggata tgtctttggg ggtgaccggg ccgctggcgg ggctggtgat
     8941 gacctgggcg ggcgtgccgg tgatttatct ggcggcggcc gggctggtag cgatggcgct
     9001 attactgacc tggcgcttaa aaaaacggcc tccgtctgca ctgccggagg ccgcatcatc
     9061 gtcgtgaagg ttacttaata accaacgtat tgatgatgtt ttcagctgtg gtttgcgctt
     9121 tttgctgatt gtccgcaggc agcgtgacct gaatcgtcag caattggtta tccactttgc
     9181 ccagcacgat ggaagagtac gccgtctggc ctttcgcgga gataatgctg tccagctgtt
     9241 gcaacgtatg gcctttgagc tcaatagact tattggtgac gacctgaagc tgcgggtcgc
     9301 ggctacgctg ttgctcaagc aggcggttcg ccagcaccgg caacgcttca tcggtattat
     9361 cgccgacgat aacaatcacc gctttctggc ccgtcgggtc agaataaacg tgcatattat
     9421 tcgcctgggt gcccagctta ccgctttgat cggtcatatc cgccggcagt gagaaactga
     9481 gtttgccatc catcaggctg atgggctgac cggaggcctg gctttctgcg gcggcgcttt
     9541 ctgccgacgc ttttgtatcg ttgttatcac aggccgcaag ccccataacc agcaggccaa
     9601 taccggcata tttaaccaaa ttgcgcattg acttcttcct ttcgataaac ggccataacg
     9661 gctcattcgc tcatcttatc acaactcgga aaacgaacct ttaacttgcc ggtaatgggg
     9721 aaatttcaga tttatctgcc agctttttca gcaacatatt cagtagaacg ccgtacatcg
     9781 gcaggaagaa aataatgctg atgagcactt taaagcaata atccaccagc gcaatttcca
     9841 tccagtgccc ggccataaag gcatcggggc ttcgccagaa cgcaatgaag aaaaaggcaa
     9901 gggtatcgct gatattgcca aacagcgttg aagcggtcgg cgccagccac cagcgacgat
     9961 tttggcgcag gcggttaaac acatggacat caaggatctg tcccagcgcg taggccataa
    10021 agctggcggc ggcgatacgg gcgacgaaca gattaaagtt cgccaacgcg gcgaaacctt
    10081 gccaggcacc catatagaac agcgatgaca ccacatatga caccagcagc gcagggatca
    10141 tgacggcgaa gataatgcgg cgcgccagcg gtgcgccaaa aatacgcacg gtaagatcgg
    10201 tggcgagaaa aataaaagga aaactaaacg cgccccaggt cgtgtggaaa ccaaaaatag
    10261 tgatggggag ctgcaccaga tagttactgg aaatgatcac cagtaaatgg aatagcgata
    10321 gccagaacaa cgcttttatg cgctgtgatt gtgtaaacgg agtcatattg tgaccttttt
    10381 gttggatggg gtgagggaac ccaataaaga accgccgcat aatactgttt tgcgctggca
    10441 ttgcaatggc taattttcac gcaatcgtta acctgcttgg cttactgacg aagatgggcg
    10501 taaaatatcg ccgtttttct accattgaga cgaagatgag cgatctgttt tcctcccctg
    10561 accatacgct tgacgccctg gggctgcgtt gccctgaacc ggtaatgatg gtgcgcaaaa
    10621 cggtgcgcaa catgcaaact ggcgaaacat tgctgattat cgccgacgat ccggcgacga
    10681 cgcgtgatat tccggggttc tgtaccttta tggaacacga tttgctggcg caagagacgg
    10741 agggtctgcc gtaccgctat ttattgcgta aagcgcatta accgcacggc agatagcatt
    10801 ctgattagaa gctttcccag ttcgcctgtt ctgcggcggg ctgtggcgtt aagcctttgc
    10861 ttaacggcgt cggcgacgcc tcccgacgag gttgtttctg gatgcggaac gcggcgaccg
    10921 cctgacgaag ctcgttagcc tgatcttcca gcgccgccgc tgctgctgcg gattcctcta
    10981 ccagcgaggc gttttgctgc gtcacgctgt ccatttccga taccgcctgc gccacctgct
    11041 caatgccttt gctttgctca tcggaggcag aggcgatttc gcccataata tcggtcacgc
    11101 gggtcacggc gttaacgatc tctttcatgg tttctcccgc ttcgcgtacc tgcgtagagc
    11161 cggtatcaat gcgcgacacg gagttttcaa tcagcacttt gatctctttg gcggcctgcg
    11221 cgctacggct ggccaacgtg cgtacctctc cggccacaac cgcgaatcct cgcccctgtt
    11281 cgccggcgcg ggcggcttct accgcagcgt tcagcgccag gatattagtc tggaaggcga
    11341 taccgtcaat cacgctggtg atgtccacga ttttttccga gctttcggcg atatcgttca
    11401 tggtgctcac tacgttatcc accacgcgtc ctcctttacg cgcggtttct gatgcggttt
    11461 tcgccagacc cgtcgcctgt cgtgcgttat cggtgttttg ccgtaccgtg gcggttaact
    11521 gttccatgct ggcggcggtc tcctccagcg ccgaggcctg ctgttcggta cgggaagaga
    11581 ggtcgctgct gccagcggaa atttcgcctg cgccagtata gatagagtct gcgttatcgc
    11641 gcaccgcgct gacggtacgg attaacgact gctgcatcgt tttgagaccg gcagccagtt
    11701 ggcccatttc actacgtcct tcagcctcta tctcatgggt aagatcgccg tcggcgatcg
    11761 tttgaatgtg cgccataatc cgttgcagcg ggcggagtag aacgcgttgc agccccagcc
    11821 agataaacgc cagcacgatg agcacgataa gtagaattat ccccagcgtc cattgcatct
    11881 gggtaaaact gctctgattc tgatcgctgg ctaattttat taattgcgca ttttgagaga
    11941 gccactggtc atatacctgc tccatgtcat cctgcgcttt ttgcgcgtca aggttgccat
    12001 aggcggcgta attatcggct ttaagatagt ggatagactg ctgcaaaacg tcatacatct
    12061 gcttaaagct ggcttcggcc tgggcatcca acgccggatc tttgcctgcg atcgcttcgg
    12121 agttcacgta gttgttgaaa tgcttttccg cttcgttgag cgacgcgcca gcgttggtta
    12181 acagcgtgtt catggcgtcc agcgaggcgg gatcgcgctg attttttaac atgcgtatcg
    12241 ccacgcggtt aatggtgacg cgggtttcaa tcaatgtctg aaaactgccg cccagttcct
    12301 gttgttggta actcagtgcg ctcgcattct ggaaattcag ccgatcgctg ctgacggcgg
    12361 aataaaacag tattcctgtc accaacaata aggcgctaaa tatgcccagc gtcgcgataa
    12421 cgccggtgat gactttgata tttttcatag tgcctaacat tccttatttt gtagacggta
    12481 tgatcaatat cggttggata aaaattaacc ttacatcaaa tcgcgctatt tctgattaat
    12541 ggtttgataa gtaatagaaa ataaatgatt ttcgcgtgaa taatatgtac aaagaaagga
    12601 atatcgcggg ataacccggc gacatgccgc cgggtgggag aagattagtt tttacgcagc
    12661 aaacgtagcg cgttggcggt cactaatacc gtggctcccg tatccgccag gattgccagc
    12721 catagcccgg taaaacccag tagcgtcgtc accaggaaaa tggctttcag ccccagcgca
    12781 atggtgatgt tctgccggat attcgcgtgg gtagcgcgcg ccagcgtaat catctgcgct
    12841 aacccgcgca gacggttatg agtaagggcg gcgtcagccg tttccagcgc gacgtcagta
    12901 ccgctgccca tcgcaattcc gatactggcg gctttcatcg cgggcgcatc attaatgccg
    12961 tcgcccacca tcgccagcgg cgcttgttgg ttaagggcgg tgactgcccg caccttatct
    13021 tccggcagta gtccggtttt aaacgccaga tccagctcgc cggcaatcgc tgccgccgcc
    13081 cgtgggttat cgccggtcag aatcacgccg ttaacgccta actgatgcag ttcgcggatg
    13141 gcgtcgcgcg catcgtcacg caacgtatcc tggagggcga ggacgccaac aacggtctcg
    13201 ttacgtagca ccagaaccac cgtctgcccg gcgttttcca gttcgctaat ttgcccggca
    13261 aacgctgccg caggctgttt tcccgccgcg caaatcagaa tacgttcgcc gttaacctgc
    13321 gcttcaatcc cggtgccggc cagcgttcgc tgcgattccg ccgtcgggat cgccagatcg
    13381 cgtgtctgcg cttcgcggac aatagcctgc gccagcgggt gcgtagcgcc ttgttctacg
    13441 gctgccgcca gcgccaacag ttcagcctcg ctgataccgc ttgccggatg aatcgccgtc
    13501 acccgtggtt taccgatggt caacgtaccg gttttatcaa aggcaacctg cgtgatacgg
    13561 cccagttgct ccagcgctgc tccgccttta atcaatgcgc cgcgccgtgc cgccgccgcc
    13621 agcccggagg taatggccgc gggcgtggag atcaccagcg cgcacgggca accgattaat
    13681 agcagcgtca gccctttata aatccactcc tgccagccgc catcgaacat cagcggcgga
    13741 ataagcgtca ccagcagcgc gatgaccata atgactggcg tatagatgcg gctgaaacgg
    13801 tcaataaacc gctcaatggg cgcacggcgc tcttccgcct cttcaatcag cgtcaggata
    13861 cggtcaatcg cgctggcgcc aggttcagat agcacctcca gggtgacgag acggtcaacg
    13921 ctggtcgcgc ctgccgggac tttgtcgccc gttgcgcgct ccacagggat agactcgccg
    13981 gtgagcgcgc tttcatcaaa gctggcgaaa ccggaaacca gtttaccgtc ggcgggtaaa
    14041 cgccccccgg cggcgacttc gataatatcg cccggtcgca gggtattaat agcgacctct
    14101 tcccgcacgc cgtcgcgcag acgggtcgcc gtttccggtt taagcgccat taacgcgctg
    14161 acgcctttac gggcgcggct ggcggcccat ccttccaggc gctcgccgat gaggaacagc
    14221 agcaatacca ttgctgcctc cgccgtcgcg cctataaaca gcgcgccaat ggcggcgacg
    14281 ctcatcagcg tttcaatagc gaaccaactg ccgcttttca tcagccgcag cgcctggcgg
    14341 gcaataggat acagaccgac cagagtggtg acgataaagg ccagttggcc gaacgggtgg
    14401 ttaaattgct ccagccccca gcttatcgcc atcataatga tcagcgtaat aagcggcagg
    14461 ttctctttaa gacgagattc aggcgcggcg tcgcgcgaat cttcactacg caaggtataa
    14521 cccgccttct gtacggcgtg ttcaatttgc gcgcggaggt cggtgtcggc atcgaccact
    14581 aacttttcgg tggcgaacag cacttgcgcc tggttgacgc cgcgaatttg gcgtaccgca
    14641 ttctccactt ttcgggcgca ggcggcgcag tccatgccgg agattttcca ggtatagcgc
    14701 gtgcctgcca cggcagtaga aacaggcgcg ctggacgcgc aatgttcttc gcagcagcag
    14761 ctatcggcct tctgtattgc cggggctaat ctgaaggagg taaagggcgg gacttttttg
    14821 ccatcggtat caggggtcga cataacgtcc tccggttgat gataattttc tcattaaccg
    14881 gaggatacac tctggagtcg actccagagt caagcgctat tatttacagg tacagcgagc
    14941 gaacaatcag gaagtgtcct gcaaagtagc aggcggcggc aatcgcgtta tccgcccgga
    15001 aacggcggcg gtaatggcta cccagccaga cgatattgcc gatgaacagc agcgtcgcgc
    15061 cggtaaaggc cgaaagggct ggcgccgttg ggcggaagaa ccacagttcg cccgccagcc
    15121 agaccatgac cagcgtcatg gcgataaaag tacataccgg ccagcgtagc tcctccagtc
    15181 gcgtccagat aacggcgata agcaacgcgc cgactatcag taacgccagc ggcagcggcc
    15241 agaagaacga caacgtcatt tggctggcaa agtaaatggt gtagagcaga tgcgataaga
    15301 aaaatgcccc gacggcgtac agcaggcgtt gacgcggtaa gagcgttaac gcatcgccga
    15361 ccagcgaggc gcacagtccg gccaacacaa gataactgat ggcgtcaaac atcggcgctt
    15421 gccaggccag taacagcaac agtaataacg tgacgggctt aaaaacccag cgttgccagg
    15481 ctggcccgcg ataggaggcg tccacataca gccatgcgga caggcagaca gcgataaacg
    15541 accaaagcat cttaattcct tgaattcgtt attttttcgc aaacggtatg cttgcggctc
    15601 tattattcag tgtagaggcc gtgacggtca gatgacaaca ctataacggg cagggtatgc
    15661 ttatttccgc attttctgac aggttaacag tatgagtaag ccaccgcttt tcttcattat
    15721 aatcattgca ttaatcgtag ttgccgcgtc gttccgcttc gttcagcaac ggcgggaaaa
    15781 agccgctaat gaggcggcgc cgttacagca aaagcaggtc gtggtcagca ataaacggga
    15841 gaagccggtt aacgaccgac gctctcgcca gcaggaagtg agcccggcgg gaaccagtat
    15901 gcgctatgag gccagtttta agccgctcaa tggcggtctg gaaaaaacgt tccgtttaca
    15961 agcgcagcag taccacgctt tgacggtggg cgatcaaggt acgctaagct ataagggaac
    16021 gcggttcgtc ggatttgtta gccgtacccc ggataacgaa taaaccgtca tccggcagca
    16081 aacgttattt tttgttctta aacttcttct gccagaccag cagctcaaac acgctgaaca
    16141 ggaaaatgcg gattttctct cccgtcgtca tctgcggacc cgctttcggt atcgttgatt
    16201 tcagcaacgc caactgcata ccgtgcatca gcgccatgaa caccaacgcc acgttgacga
    16261 agatattgag cgggcgcggg aagggatgca ccagattaag aatcaaaaat gcccacacga
    16321 agagcattaa taagcggccc agattaatca acatcatttt ctccttgcgc gtcgcgctga
    16381 tacagacgat aagcgacctg tccggccacc ttttctcgat acaatgccca gttcgccgga
    16441 acgggcggca gaccgttttc cacctcgctt tctacgtaga ttagcgcgtc gtcggccagc
    16501 catccctggg tttctagcaa ttgtaacgtc tcttccagca gtcctttacg aaacggcggg
    16561 tcgacaaaga cgacgtgatg cggcgtcccc ggctggctga ggaaggccag agtattggta
    16621 ttgacgacgc gagcattgtt ggctttcagc gtcgccagat ttttttgcaa ctgctgcgat
    16681 acggcgcgat ccatttccag taacgttgcc tgggccgcat aacgcgatag cgcttccaga
    16741 cccagcgcgc cgctgccggc aaagcaatcc agacaatggg cgtctaccat taccggagcc
    16801 agccagttaa ataacgtttc gcgcacgcga tcggtggtag gacgcagacc cgggctgtcc
    16861 ggaaccggta atttacggcc acgccattgc ccgccaataa tgcggatttg gccgctgcca
    16921 gagtgagtcg gttttttcat ttctcttgct cgaaccgcct gttgcaagtt attccaggcg
    16981 gtgatgtgaa ttaagttaag tgatagacta tttcatcatt tttttagctt ccatgtatat
    17041 agcgccgcga ggggtgtagt cgcagatggc aaaacagaaa aaacgtggct tcttttcctg
    17101 gttgggcttc ggtgataaag agcagaagca ggaacagacc gaagaacagc agattgttga
    17161 ggaacaacga ccggttgagc cccctgttga aacggcggca gacgtagacg cgcaaacgcc
    17221 cgcgcacagc aaagcagaaa cagaagcctt tgcggaagag gtggtggacg ttactgagaa
    17281 agttcaggag agcgaaaaac cgcagccggt agagccggag cccacggcgg ccattgagat
    17341 ggcagcgccg cagatcgcgg tggaacgcga ggaattgccg ctgccggaag aggtcaaaga
    17401 cgaggctatc tcgccggaag agtggcaggc cgaagcggaa accgtagagg tcattgccgc
    17461 ggtagaagaa gagggcgaaa acgcggcgaa attcaccgac gaagagctgg aagcgcaggc
    17521 gctggccgct caggcggcgg aagaggcggt gatggttgtt ccgccggcgg aagaagacgc
    17581 gccggtggaa gcgatcgttc aggagcagga aaaaccgact aaagaaggtt tctttgcccg
    17641 cctgaaacgc agtctgctga aaaccaaaga aaatctcggt tccggattta tcagtctgtt
    17701 ccgcggcaag aaaatcgacg atgatttgtt cgaggagctg gaagagcagt tgctcatcgc
    17761 tgatgtcggg gtggaaacca cgcgtaagat tatcgctaat ctgacggaag gcgccagccg
    17821 caaacagctt aaagatgccg aggcgctgta tggtctgttg aaagacgaga tgggcgagat
    17881 tctggcgaag gtagacgaac cgcttaatat tgaaggtaaa acgccttttg ttattctgat
    17941 ggttggcgtg aacggcgtgg gtaaaaccac cactatcggt aaactggcgc gccagtttga
    18001 gcagcagggt aaatcagtga tgctggcggc gggggatact ttccgcgcgg cggcggtcga
    18061 acagctacag gtctggggac agcgtaacaa cattccggtt atcgcccagc ataccggcgc
    18121 ggactccgcc tcggtgattt ttgacgctat ccaggccgcg aaggcgcgta atgtggatgt
    18181 gttaattgcc gatacggcag ggcgtttgca gaacaagtcg cacctgatgg aagagctgaa
    18241 aaaaatcgtt cgcgtcatga aaaagctgga cgaagaagcg ccacatgaag ttatgctgac
    18301 cattgacgcc agcaccggac agaacgcggt aagccaggcc aaactgttcc atgaagcggt
    18361 gggcttaacc ggtattaccc tgaccaagct ggacggtacg gcgaaaggcg gggtgatttt
    18421 ctcggtagct gaccagtttg gcattcctat ccgttacatt ggcgtgggcg aacgtatcga
    18481 ggatttgcgt ccgtttaagg cggacgattt tattgaggca ctttttgccc gagaggatta
    18541 acaatgattc gctttgaaca tgtcagcaag gcctatctcg gcgggagaca agcgctgcag
    18601 ggagtgacat tccatatgcg gccaggcgag atggcgtttc tgaccggcca ctccggcgcg
    18661 gggaaaagta ccctgctgaa gctaatctgt gggattgagc ggcccagcgc cggcaaaatc
    18721 ttcttcagcg ggcatgatat tacgcgcctg aaaaaccgcg aagtgccgtt tttgcgccgc
    18781 cagattggga tgattttcca ggatcaccat ctgctgatgg atcgcacggt ctatgacaat
    18841 gtggcgatac cgttaatcat tgccggcgcc agcggcgatg atatccgtcg tcgtgtgtcg
    18901 gcggcgctgg ataaggttgg actactggac aaagcgagaa acttcccgat tcaactctcc
    18961 ggaggcgaac aacagcgcgt gggcatcgcc cgcgcggtgg tcaataagcc agcggtattg
    19021 ctggcggatg aaccgaccgg gaacctggac gacgcgttgt cggaagggat tttacgtctg
    19081 tttgaagagt ttaaccgcgt aggggtgacg gtactgatgg cgacgcacga tattggactt
    19141 atctcgcgtc gttcctatag gcagctcgtc ctgagcgatg gacatctgca tggaggcctg
    19201 gccaatgaat aggcgcgacg cgattaacca aatcaggcag ttcggcggac ggctggatcg
    19261 actgcgtaag tctcgcggcg gaacaggcgg cgggcgcaac gcgccaggac gccagaagcc
    19321 gacgccgaaa ccgaactcac gtaaaacaaa tgtttttaat gaacaggtgc gctatgcttg
    19381 gcacggtgcg ctgcaagatc tgaaaagcaa accgctggcg acgtttctga cggtgatggt
    19441 gatcgccatc tccctgacgc tgcccagcgt ctgttacatg gtctataaga acgtcaacca
    19501 ggcggcgact cagtactatc cgtcgccgca gatcaccgtt tatctgcaaa aaacgctgga
    19561 tgatgacgcg gcggcgcggg tcgttgggca gcttcaggcc gagcagggcg ttgagaaggt
    19621 caactacctg tcccgtgagg acgcgctggg cgaattccgc aactggtcgg gttttggcgg
    19681 cgcgctggac atgctggaag agaacccgct accggcggtg gcggtggtga tccccaagct
    19741 ggactttcaa agtaccgcct cgcttaatac gctgcgcgac cgtatctcgc agattaacgg
    19801 cattgacgaa gtccgcatgg atgatagctg gtttgcgcgt ctggcggcgc tcaccgggct
    19861 ggtgggccgc gtgtcggcga tgattggcgt gctgatggtc gcggcggtct tcctcgttat
    19921 cggcaacagc gtgcgcctga gcatttttgc ccgtcgcgac accattaacg tgcaaaagct
    19981 gattggcgcg accgatggct ttatcctgcg tccgttcctc tacggcggcg cattgctcgg
    20041 tttttccggc gcgtttcttt cactgatatt gtctgaaatt ttggtgatgc gtttatcatc
    20101 ggcggtgact gaagtggcgc aggtcttcgg cacgaagttt gatctcaatg gtttatcgtt
    20161 cgatgagtgc ctgttgctgc tgctggtctg ttccatgatc ggctggatcg ccgcttggct
    20221 ggctacggtg caacatttac gttactttac tcccgattga taaaatcgtg gtataatctt
    20281 tccctgcaat gggcttccgt tcgcagggaa agagtccctg ttgtctcttc cccgcgtttc
    20341 atcttcatgt cacattatgt gtgtaaatta tgcacagtgt tacattgaac ttgtggataa
    20401 aatcactgtc tgataaaaga gtggatgata ttctcgttgc tcatcggctt tggcacggtt
    20461 gttgctcgct gacggtgcca ggcaatactg attgagagga tttgaatgac caaagaaatg
    20521 caaaatttag ctttagcccc tgttggcaac ctggaatctt atatccgggc ggcgaacgcg
    20581 tggccgatgt tatcggctga cgaggagcgg gcattggctg aaaggctgca ttaccagggc
    20641 gatctggaag cagctaaaac gctgatcctg tctcacctgc gctttgttgt tcatattgct
    20701 cgtaactatg cgggctatgg tctgccgcag gcggatttga tccaggaagg caacatcggc
    20761 ctgatgaaag ccgtacgtcg tttcaacccg gaagtaggcg tgcgcctggt ctccttcgcc
    20821 gtacactgga ttaaagcaga aattcacgaa tacgtgctgc gtaactggcg tatcgttaaa
    20881 gtcgcaacca cgaaagcgca gcgtaagctg ttctttaatc tgcgtaaaac caagcagcgt
    20941 ctgggctggt ttaatcagga tgaggttgaa atggtggcgc gcgaactggg tgtttccagt
    21001 aaagacgtgc gtgagatgga gtcgcgtatg gcggcgcagg acatgacgtt tgacatgtct
    21061 tcggacgatg agtccgacag ccagccaatg gcgccggtgc tgtatctgca ggataaatcg
    21121 tctaactttg ccgacggcat tgaagacgat aactgggaag agcaggccgc taaccgactg
    21181 accgatgcga tgcaggggct cgacgagcgt agccaggata ttatccgcgc tcgctggctg
    21241 gacgaagaca ataagtctac gttgcaggag ctggccgatc gttacggcgt ctccgctgag
    21301 cgtgtgcgcc agcttgaaaa gaacgccatg aaaaagcttc gcgctgcgat cgaagcgtaa
    21361 tcttcgcgaa ttgccaatga accctcgaat gtgaattcgg gggttttgtt ttttgtaggc
    21421 cggataaggc gtttacgctg ctatccggca acacgtttgc ccgatgtcgc ttcgcttatc
    21481 tggcctacgg gcccttcctc tcccccaccg acacaaatct gttatctgga tgtaaattta
    21541 gctattccaa aataataaaa atcgggtatg ttttagcaga gtatgctgct aaagcacggg
    21601 tagctagcca ataatcgaaa taaagtgctg aacaataaca ccacaacaca cgtaacaacc
    21661 agaataatgg ggattatcag gatgaatatg aagggtaaaa cgttattggc aggatgtatc
    21721 gccctgtcat taagccatat ggcattcgca gaggacatta aagtcgcggt tgtcggcgcg
    21781 atgtccggtc cggtggcgca gtatggcgac caggaattta ccggtgcgga gcaggcaatt
    21841 gccgatatca atgcgaaagg cggtattaaa ggcgataagc tcgtcgcggt gaaatatgac
    21901 gacgcctgtg atccaaaaca ggcggtagcg gtcgctaaca aagtggtgaa cgacggcatc
    21961 aagtatgtta tcggtcactt atgctcctct tccacacagc cagcgtctga tatctacgaa
    22021 gacgaaggca tcctgatgat aaccccggcg gcgaccgcac cggagctgac cgcgcgcggc
    22081 tataacctga ttttgcgcac gaccggcctg gactctgact agggaccaac ggcggcaaag
    22141 tatattctgg agaaggtaaa accgcagcgc atcgcgatta tccacgataa gcagcagtac
    22201 ggcgaagggc tggcgcgcgc ggtgcaggac ggtctgaaga aaggcggcgt taacgtcgta
    22261 ttctttgacg gcattaccgc cggcgaaaaa gatttctcca ctctggtagc gcgtctgaaa
    22321 aaagagaata tcgactttgt ctactacggc ggttatcacc cggaaatggg gcagattttg
    22381 cgccagtccc gcgccgcagg gctgaaaacc cagtttatgg ggccggaagg ggtggcgaac
    22441 gtctcgctgt ctaacatcgc cggagagtcg gcggaaggct tactggtcac caaaccgaag
    22501 aactacgatc aggtcccggc gaacaaaccg attgtggatg ccatcaaagc caagaaacaa
    22561 gatcctagcg gcgcattcgt gtggaccacc tacgccgcgc tgcaatcgtt gcaggcgggt
    22621 ctgaaccagt ctgacgatcc ggcggaaatt gccaaatacc tgaaaggcac cacggtcgac
    22681 accgtaatgg gaccgctgtc gtgggatgag aaaggcgatc tgaaaggatt tgagttcggc
    22741 gtgtttgact ggcatgcgaa tggtacggcg acagacgcta agtaattttc ctggcgcctt
    22801 tcgcgctgca ggtgcgttgg ctacgttatt caaccccggt cacttactta tgtaagcttc
    22861 cggggatttc ataacttgcc gcctgcctgc aacgcgaaat tcttggaaaa ttgcgaggtg
    22921 gtttttatct tttctcccgg catgtaggcc ggataagcgt cagcgccatc cggctttctt
    22981 ttagcgcttc tcccagccgt catgctgggc ggtaaaacct aacgcctgca taaacgcggc
    23041 catcacgctg cggtcttcaa caccgacatc cgccatccac cacgacgaga cgttgggatt
    23101 atcgcggatg acctcttcta ccaggtattg cccgacgccg cggcgacggg tgatttcacg
    23161 cacgcgtaag gaatccagcg cgccctgcgt tccgctcagc gtcactctta cggcgcccaa
    23221 caaacgctcg ttaaaccgcg cggcataaat ccggtgcgtt tcatctacgc ttaatgagga
    23281 ggcggaatat tccggccaga ttttgcccag atcgatctga tcctgagcgc taaagtgttc
    23341 taaacgaaga atggtcagct tcatcgacgg cttgtcccga tttcaaaaga tgcgatcagt
    23401 gtaccgaaac aggcaggcca gatgctttct cttttttgtg tcatttacca ggttattaat
    23461 tttttaacaa cgataattac agtttgaagc attagagaat ggaaaacagg cagcataatt
    23521 ccctgaatgc tagtgaatta ttccgcttaa tgtgccgtta ttttatgctg acaagcgtgc
    23581 ttttttttgt ttatctataa cgaaaagcag aatattatat tttcttaata gactgaaaaa
    23641 tagagatttt aatcttatta tgctttaaat gctgcgctaa ctcattaatg agtcagtaaa
    23701 aagcgcacca tttataaaaa gtacagtctg ctttttaacc agtaaaaaac aaaacatata
    23761 acatcacgaa tggggataca ggcacatgaa acggaaagcg aaaacaataa tcgcagggat
    23821 tgttgcatta gcagtctcgc agggggcaat ggcagatgat attaaagtcg ccatagtcgg
    23881 ggcgatgtcc ggcccggtag cgcaatgggg cgatatggaa tttaacggcg cgcgccaggc
    23941 cattaaagac atcaatgcta aaggcggtat taaaggcgat aagctggtcg gcgtagagta
    24001 cgatgatgcc tgcgatccaa aacaggcggt ggcggtggcc aacaaaatcg ttaacgacgg
    24061 tattcagtac gttattggtc acttgtgttc ttcttctact cagccagcat ccgatatcta
    24121 tgaagatgaa ggtattctga tgatctcccc gggggcgact aacccggagc tgacccagcg
    24181 cggctatcag tacattatgc gtaccgccgg cctggactcc tcccaggggc caacggccgc
    24241 gaaatacatc ctggaaacgg tgaaaccgca gcgcatcgct atcattcacg ataaacagca
    24301 atacggcgaa ggactggcgc gctccgtgca ggatggcctg aagcagggca atgccaatat
    24361 tgtctttttt gatggtatta ccgccggcga aaaagatttc tccgccctga ttgctcgctt
    24421 gcaaaaagag aatatcgact ttgtgtatta cggcggctac tacccggaaa tggggcagat
    24481 gctgcgccag gcgcgggcta atggcctgaa aacgcaattt atggggccgg aaggcgtggg
    24541 taacgcgtcg ctgtccaata ttgcgggcgg tgcggcggaa ggcatgttgg tgacgatgcc
    24601 aaaacgttat gaccaggacc cggcgaataa agcgattgtc gaggcgctga aagccgacaa
    24661 gaaagatccc agcggtccgt atgtctggat cacctacgcc gccgtccagt cgctggcgac
    24721 cgcaatgacg cgtagcgcca gccatgctcc gctggatctg gtgaaagatc ttaaagcgaa
    24781 cggggctgat accgttattg ggccgctgaa atgggatgaa aaaggcgatc ttaagggatt
    24841 tgaatttggc gtcttccagt ggcacgccga cggctcgtca accgtcgcga agtaatgcca
    24901 gaagataagt tatcccaccg cccgcacgcc gggcgggttt aaaaaggtta ccttatgtcc
    24961 gagcagtttc tctatttctt gcagcagatg tttaacggcg tcacgctggg gagcacctac
    25021 gcgctgattg ctatcggtta tacgatggtg tacggcatta tcggcatgat caacttcgct
    25081 catggcgagg tgtatatgat cggcagctac gtctctttta tgatcatcgc cgcgctaatg
    25141 atgatgggaa tagacaccag ttggctactg gtggccgccg gatttatcgg cgcgattatt
    25201 attgccagcg cctacggctg gagtatcgag cgagtcgctt accggcctgt gcgcaattcc
    25261 aagcgcctga tcgccctgat ttccgccatc gggatgtcca tctttctgca aaactacgtc
    25321 agcctgacgg aaggttcgcg cgacgtggcg ttacccagcc tgtttaacgg ccagtggatt
    25381 gtgggcagca gcgaaaactt ttccgcgtcc atcaccacca tgcaggcggt tatctggata
    25441 gtcacctttc tggctatgct ggcgctcacc attttcattc gctactcccg gatgggccgc
    25501 gcctgccgcg cctgcgcgga ggatctgaaa atggccagcc tgctcggcat taataccgac
    25561 cgcgtcattg cgctaacgtt tgttatcggc gcggcaatgg cggcggtggc gggcgtgctg
    25621 ctcggtcagt tctatggcgt gattaacccc tacatcggtt ttatggccgg gatgaaagcg
    25681 ttcaccgcgg cggtgctggg cggtattggc agcattccgg gcgcgatgat cggcggtctg
    25741 attttgggcg tcgccgaagc gctctcgtct gcatatttaa gtaccgaata taaagatgtc
    25801 gtgtcgttcg ctctgctgat tctggtactg ctggtgatgc cgaccggtat cctggggcgt
    25861 ccggaggtag agaaagtatg aaaccgatgc atattgcgat ggctctgttc tctgcggcga
    25921 tgttcttcgt tctggctggc gtctttatgg gcgtacaact ggagctggac ggcaccaaac
    25981 tggtggtgga taccgccgcc gacatccgct ggcagtggat ctttatcggt acggcagtgg
    26041 tttttttctt tcagttgctg cgtccgatgt tccagaaagc ggtgaagcac gtctccggac
    26101 cgaagtttat tctgccggcg atcgatggct ctaccgttaa gcaaaagctg tttctgatgg
    26161 cgctgttggt tatcgccgtg gcgtggccgt ttatggtgtc gcgcggtagc gtcgatatcg
    26221 ccactatgac catgatttat atcatcctcg gtctggggct gaacgtggtg gtggggctgt
    26281 ccggcctgct ggtattgggc tacggcggct tttacgccat cggcgcttat acctttgcgc
    26341 tgcttaacca ctattacggt ttgggtttct ggacctgcct gccgctggcg ggactggtct
    26401 ccgccgccgc cggtttcctg ctcggcttcc cggtactgcg cctgcgcggc gactatctgg
    26461 cgattgtgac gctcggcttc ggcgaaatcg tccgtatcct gttgctcaac aacactgaaa
    26521 ttaccggcgg cccgaacggc atcagccaga tccccaaacc gacgctgttt ggtctggagt
    26581 ttagccgcaa cacccgagaa ggcggctggg ataccttcag caatttcttt ggcgtgaagt
    26641 acgacccatc cgaccgggtc attttcctct atctggtggc cctgttgctg gtggtcctgt
    26701 cgctgtttgt cattaaccgc ctgctgcgta tgccgctggg ccgggcgtgg gaagcgttgc
    26761 gtgaagatga gatcgcctgt cgctcattag gtttaagccc gacgcgcatc aagctgaccg
    26821 cttttactat cagcgccgcg tttgccggtt tcgccgggac gttgtttgcc gcccgccagg
    26881 gctttgtcag cccggaatcc ttcactttcg ccgaatccgc cttcgtgctg gcgattgtgg
    26941 tgctgggcgg aatgggctcg cagtttgcgg tgatcctggc ggcggttctg ttggtggtgt
    27001 cgcgcgagtt gatgcgcgat ttcaacgaat acagcatgtt gatgctcggc ggtttaatgg
    27061 tgttgatgat gatctggcgc ccgcagggat tgctgccgat gacgcgtccg cagttgaagc
    27121 tgaaaagtgg tcaggcgaaa ggagagcagg catgagtcag ccattattag cggttaacgg
    27181 cctgatgatg cgctttggcg gtttgctggc ggtcaacaat gtatcgctgg aattgcgtga
    27241 gcgggaaatt gtgtcgctga ttggccctaa cggcgcgggt aaaacgacgg tgtttaactg
    27301 cctgaccggt ttttataagc cgacaggcgg tacgatcacg ttgcgcgagc ggcatctgga
    27361 aggattgccg ggccagcaga tcgcccgcat gggcgtggta cgcactttcc agcatgtgcg
    27421 cctgtttcgc gaaatgacgg tgattgaaaa cctgctggtg gcgcagcacc agcaactgaa
    27481 aacgggcctc ttttccggcc tgttgaaaac gcccgctttc cgccgcgcgc aaagtgaagc
    27541 gctggaccgc gcggcgacct ggcttgagcg tattggcctg ctggaacatg ccaaccgcca
    27601 ggccagtaat ctggcctacg gcgaccagcg ccggctggag attgcccgct gcatggtgac
    27661 gcagccagaa attctgatgc tcgacgaacc ggcggccggc cttaacccga aagagaccaa
    27721 agagctggat gagctgattg ccgaactacg taaccatcac aacaccacta tcttgctgat
    27781 tgaacacgat atgaagctgg tgatgggcat ttccgatcgc atttacgtgg tgaaccaggg
    27841 cacgccgctg gcgaacggca cgccggaaga gatccgcaac aacccggacg tcatccgcgc
    27901 ttatctgggt gaggcataag atggaaaaaa cgatgttaac gtttgaaaaa gtcagcgccc
    27961 actacggcaa gattcaggcg ctgcacgacg tcagtctgca catcaaccag ggggaaatcg
    28021 ttaccctgat tggcgctaac ggcgcgggga aaacgacgct gcttggcacc ttgtgcggcg
    28081 atccgcgcgc ctccagcgga cgggtggtgt ttgacggtaa agacatcacc gactggcaga
    28141 cggcgaaaat catgcgtgaa gcggtggcga tagtgccgga agggcggcgc gtcttctcgc
    28201 ggatgacggt ggaagagaac ctggcgatgg gcggtttttt tgccgagcgc gatcggtttc
    28261 aggagcgtat caaatgggtg tacgagctgt ttccgcgcct gcatgaacgc cgtatccagc
    28321 gagcgggcac catgtccggc ggcgaacagc agatgctggc gattggtcgc gcgctgatga
    28381 gccagccgcg cctgttgctg ctggatgaac cgtcgctggg gctggcgccg atcatcatcc
    28441 agcagatctt cgacaccatt gagcagttgc gcgagcaggg tatgaccatc ttccttgtcg
    28501 agcaaaacgc taaccaggcg ctgaagctcg ccgaccgcgg ttatgtgctg gaaaacggcc
    28561 acgtggtgct atccgatacc ggtgatgcgc tgctggcgaa cgaagcggtg cgcagcgcct
    28621 atctgggcgg ataaggcgca gtttacagct gccatctggc aaacgcgccc ggtggcgcta
    28681 ccgcttaccg gacctggcgg attactcggc attcggcaaa tcagtagaac atttttcgta
    28741 ccaatatgtt atagttgaga atagttatca actataacca ccgaagaagg agcaaggatg
    28801 atacgttcag gcgcctgcat aatgggaacg ctgttgttcg cggcttcgtt cagtgttaac
    28861 gccttaacct caaacgattt tgatccccgc gatcctgcta tctggcaaga agaaaccgca
    28921 acgccttatc cactggccgc aacgacctgc gaagtgcgtc atcatccgga ttgtgcaacg
    28981 tgggaggatg aaaaatccga cattcagcgt gaacgcgagc ggcgagatca gcggcgctta
    29041 caaaatctgt acaaaaagta ttctcatcgt gattaactgc tgacgccagc caaataacgc
    29101 atgtctggtc agcattacgc tgtcagacgt gccgtagctc ccacttttct tttccggcgc
    29161 tttcactgcc ttgccatctc tctgtcgcct tactatcttt ttttgtaata aaaaagttat
    29221 ttttctgtca ttcgagcatg tcatgttacc cccgcgaaca taaaacgcgt gatatcgcgc
    29281 atcccggcac aaaaagagag ataaccgatg atatcgttac gacatacagc tttaggactg
    29341 gcgctgagtc tggcatttac gggtcaggcg ttggccgtca ccactattcc attctggcat
    29401 tcaatggaag gggagttagg caaagaagtt gattcactgg cgcaacgttt caaccaggcc
    29461 aatccggatt acaaaatcgt tccggtctat aaggggaact atgaacagaa cctgagcgcc
    29521 gggatcgcgg cattccgtac cggcaacgcg ccggcaatat tgcaggttta tgaggttggg
    29581 acagcgacca tgatggcctc gaaagccatt aagccggttt atgaagtgtt taaagacgcc
    29641 ggtattaact ttgacgagtc ccagtttgta ccaaccgttg caggctacta caccgatgct
    29701 aaaagcgggc atctgctctc ccagcccttt aacagctcca cgccggtact gtactacaac
    29761 aaagacgcct ttaagaaagc cggtttagat ccggagcagc cgccgaaaac ttggcaggag
    29821 ctggctgact ataccgcgaa attgagagcg gcaggcatga aatgcggtta cgccagcggc
    29881 tggcaaggct ggatccaact ggaaaacttc agcgcctgga acggtctccc cttcgccagt
    29941 aaaaacaatg gctttgacgg tacagatgcg gtgctggagt ttaataagcc agagcaggtg
    30001 aaacatatcg cgctgctgga agagatgaat aagaaaggcg attttagcta tgttgggcgt
    30061 aaggacgagt ctaccgagaa gttttataac ggtgactgcg cgatgacaac cgcgtcctcc
    30121 ggctcgctcg ccaatatccg ccagtatgcc aaatttaact atggcgtggg tatgatgccg
    30181 tatgacgctg atatcaaggg cgcgccgcaa aacgccatta tcggcggagc cagcctatgg
    30241 gtcatgcagg gtaaagataa agaaacctat accggcgtcg ccaaattcct cgacttcctg
    30301 gcaaaaccgg aaaacgctgc tgaatggcat caaaaaaccg gctacctgcc gattaccacc
    30361 gccgcctacg agctgacccg agagcagggt tattacgata aaaaccccgg tgcggatatc
    30421 gccactcgcc agatgttgaa taagccgccg ttacccttca ccaaaggctt gcgtctgggc
    30481 aatatgccgc agattcgtac catcgtggac gaagagctgg aaagcgtctg gaccgggaag
    30541 aaaaccccac aacaggcgtt ggataccgcg gtggatcgcg ggaatcagtt actgcgtcgt
    30601 tttgagaaag cgagcaaatc ttaagtgtat aagtgcctga tggcgctgcg cttatcaggc
    30661 ctacagcgtt tgtaggccgg ataaggtgct tgcaccgcca tccggcacct tccaggaaaa
    30721 gaaccttcat gtcatcatcc cgtccggtgt tccgctcgcg ctggctgccg tatttactgg
    30781 ttgctccgca gttggttatc accgttattt tctttatctg gcctgcgggc gaagcgctgt
    30841 ggtattcgct gcaaagcgtc gatccgtttg gtttttccag ccaatttgtc gggctggaga
    30901 atttcgtcgc gctttttcac gacagttatt atctcgacgc cttctggacg acgattaaat
    30961 tcagcgcgct ggtcacgttt agcggcctgc tggtctcatt gtttttcgcc gccctggtgg
    31021 attacgtggt gcgcggcagc cgtttttatc agacgctgat gctgctgcct tatgccgtcg
    31081 cgcccgccgt cgccgccgta ttgtggattt tcctgtttaa cccggggcgg ggattaatca
    31141 cccatttcct cggcgaattc ggctatgact ggaaccacgc gcaaaacagc ggtcaggcga
    31201 tgttcctggt ggtatttgcg tcagtctgga agcagattag ttacaacttt ttattcttct
    31261 ttgccgcgct gcaatctatt ccccgctcgc tggtggaagc ggcggccatt gacggcgccg
    31321 ggccgattcg tcgtttcttc cggctttctt tgccgcttat tgcgccggtc agtttcttcc
    31381 tgctggtggt caacctggtg tatgcctttt tcgacacctt cccggtgatt gacgccgcga
    31441 ccgccggcgg gccggtacaa gccaccacga cgctgattta taagatttat tgcgaagggt
    31501 ttaccggcct ggatctctcg gcgtccgccg cgcagtcggt ggtgttgatg ttcctcgtca
    31561 tcattctgac ggtggtgcag ttccgctatg tggaaagtaa ggtgcgttac caatgataga
    31621 gaatcgtcgc gggctgacaa tattcagcca taccatgctg attctgggga tcgcggtcat
    31681 tttgtttccg ctgtatgtcg cgtttgtcgc ggcgacgctg gacgaccgcg cggtgtttga
    31741 gacgccgatg acgctgcttc ccggcacgca gttactggag aatatcaaaa ctatttgggt
    31801 caacggcgtc ggtgttaata gcgcgccatt ctggctgatg atgcttaaca gtttcattat
    31861 ggcgttcagc attacggtag gcaaaatcac ggtatctatg ctttccgcat tcgccatcgt
    31921 ctggtttcgt tttcccctgc gtaacctgtt cttctggatg atttttatca ccctgatgtt
    31981 gccggttgaa gtgcgtatct tcccgacggt ggaagtgatc gccaacctga aaatgctcaa
    32041 cagctatgcc ggtctgacgt taccgctgat ggcgtccgct accgccactt tcctgtttcg
    32101 tcaattcttc atgacgcttc cggatgaact ggtggaggcg gcccgtattg acggcgcgtc
    32161 gccgatgcgc tttttccgcg acatcgtgtt gccgctgtca aaaaccaacc tggcggcgtt
    32221 attcgtcatc acctttatct acggctggaa ccagtatctg tggccgctgt tgattatcac
    32281 cgacgtgaat cttggcactg ccgtagcggg tatcaaaggg atgatcgcca ctggcgaagg
    32341 taccacgcaa tggaaccagg tgatggcggc aatgctgctg actctgattc ccccggtcgt
    32401 aattgtgtta gccatgcaac gggcgtttgt gcgtggttta gtggacagtg agaaataaaa
    32461 atggctggtt taaaactaca ggcagtaacc aaaagctggg gcggcaaaac ccaggtcatt
    32521 caaccgctga cgctggacgt ggcggatggc gaatttatcg tgatggtcgg gccgtccggc
    32581 tgcggcaaat caacgttgtt gcggatggtg gccggtctgg aacgcgtgac cagcggcgat
    32641 atctggattg atcgcaaacg ggtcaccgag atggagccca aagatcgcgg catcgcgatg
    32701 gtatttcaga actatgctct ctatccccat atgagcgtag aggagaacat ggcgtggggg
    32761 ctgaaaattc gcggtatgag caaagcgcat attgaagaac gcgtgcggga ggcggcgcgc
    32821 attctggagc tggacggcct gcttaaacgc cgtccacgcg agctttccgg cggtcaacgg
    32881 cagcgcgtgg caatggggcg cgcgatcgtc cgcgagccgg cagtcttttt attcgacgaa
    32941 ccgctctcta acctcgacgc caagctgcgc gtgcagatgc gtctggagtt acaacatctg
    33001 catcgtcgcc ttcgtaccac ctcgctctat gttactcacg atcaggtaga ggcgatgacg
    33061 ctggcccagc gggtgatggt gatgaataaa ggcgtcgcag aacagattgg cacgccggta
    33121 gaggtgtatg aaaaaccggc cagtcgcttc gtggcgagct ttattggcag cccggcgatg
    33181 aatctgttgg acggcgttat cagcgcttcc ggcgaccgtt tcgaattgcc tggcggtctg
    33241 gcgttgccga ttggtgcggg ctatcggggt catgctggac gtaaaatgac gctgggtatc
    33301 cgcccggagc atattgcgtt aagctcgcag gcggaaggcg gcgtgccgtt aacggtagac
    33361 acgctggaga ttctgggcgc ggataatctg gcgcatgggc gctggggcga tcagaaactg
    33421 gtggtgcggt tggcgcatca gcagcgcccg gcggcgggca gtacgctatg gctgcgtctg
    33481 ccggaacatc agcgacatct ttttgatggc gaaacaggac aacgtgtatg agtaactggc
    33541 cttatcctca cattgtcgcc catcgcggcg gcggtaaact ggcgccggaa aacactctgg
    33601 cggcgattga cgtgggcgcg cgatacgggc acaccatgat tgagtttgat gccaagctgt
    33661 cgaaagacgg cgaaattttc ctgctgcatg acgataacct ggagcgcacc agcaatggtt
    33721 ggggtgtggc gggcgagttg aactggcagg atttattgcg tgtggacgct ggcggttggt
    33781 ttagcggcga atttaaaggc gagccgctgc cgttgctctc gcaggtggcg gagcgctgcc
    33841 gtaaacacgg catgatggcg aatattgaga tcaaaccgac aacggggagc ggaaggctaa
    33901 caggacgtgt cgtggcgttg gccgcccgcg aactgtgggc cgggatgacg ccgccgctgc
    33961 tttcttcctt tgagatagag gcgctggaag cggcgcaggc ggcagtacct gaactgccgc
    34021 gcgggttact actggataaa tggcgtgaag actggcgtga actgacgacc cgtctgggct
    34081 gtgtttccct ccatctcaac cataaattac tcgatgagac gcgagtgcaa gagattaagg
    34141 ccgcgggtct gcggattctg gtgtataccg tcaatcagcc ccagcgggcg gcagagctgc
    34201 tgcgctgggg cgtggattgt atctgcaccg atcgcattga tgacatcggc cctcactttc
    34261 agttttaagg gctgatagtt ttcagcggga tgtcaggctg cggcgtcccg ctgtcctgct
    34321 gcaacattgg ctgggaatgg tttagcatcc ggtccggatt tccgctgccg ctgagcattc
    34381 cgccctgcgt attgggcagc gtttgctgac cgagcatacc gttgcccggc tgtccctgct
    34441 gaacccgctg cgtattggca ttcaactgcg actgtagatt ttgctgctgg ctgcgcgcct
    34501 gcgtttgcat ctgcgtctgc atacgctgct ggctggggat ttgataacct ggctgattag
    34561 gattattcat agtgttaatt ggctgggcca atacagcaaa gggtaataaa gccgtaataa
    34621 gtagtaagcg tttcattgtc gtctcctccc gatgaggcct ctttttaagt gtacctctat
    34681 ttcgccatga tgatgatttt ttaagcgttg tggaccagga ttaaacggga catacacccc
    34741 tttatctgga gaaaaacaac gatgaaacca acgtttatgc gctgggtggc gatcgccgct
    34801 ctgctggccg gggggacgtt tagcgcggtg gccaatcctc ccgtcgcgcc gccagtctcc
    34861 tatggtgttg aagaagatgt ctttcatcct gtacgggcga cgcaagggat ggtggcgtcc
    34921 gtggatgcaa tggcgacgca ggttggcgtg gatatcttaa agcagggcgg taatgccgtg
    34981 gatgccgccg tcgccgtggg ctatgcgctg gctgtcacgc atccgcaagc cgggaatctg
    35041 ggcggcgggg gatttatgct gctgcgcact aaagatggcg ctaccacggc gatcgatttt
    35101 cgtgaaatgg cgccggctgc cgcgacccgt gatatgttcc tcgacgatca gggtaacgcc
    35161 gatgcgaaaa agtcgctgac gtcgcatctg gcatccggta cgccgggtac cgtggcgggt
    35221 ttctcgctgg cgctggagaa atacggcacg atgccgctga ataaagtggt gcgtccggcg
    35281 atgaagctgg cggaagaggg ttttgtggtt aacgatgcgc tggccgacga cttaaaaact
    35341 tacggcagcg aagtgatccc caaccatgag aacagcaaag ccattttctg gaaagacggc
    35401 gagccgctga aaaaaggcga taagctgatc cagaagaatc tggcgaaaag cctggaaatg
    35461 attgccgaaa acggcccggc tgcgttttat aaaggggcga ttgccgacca gattgccggg
    35521 gaaatgcaga agaacggcgg tctgatgacc aaagaggatt tagccagcta taaagccgtt
    35581 gagcgtacgc caatcagcgg tgactatcgc gggtatcagg ttttctccat gccgccgccg
    35641 tcctcgggcg gtattcacat cgtgcaaatc ctcaatattc ttgaaaattt cgacatgaag
    35701 aagtacggct ttggcagcgc cgatgccatg caaatcatgg cggaagcgga aaaatacgcc
    35761 tacgctgacc gctcagagta tctgggcgat ccggactttg tgaaagtgcc gtggcaggcg
    35821 ctgaccaaca aagcctatgc gaaaacgttg gccgatcaaa tagatattaa taaggcaaaa
    35881 ccttccagcc agatcaaacc gggcaagctc gccccgtatg aaagcaacca gaccacccac
    35941 ttctcggtgg tggataaaga cggcaatgct gtggcggtga cctataccct gaacaccacc
    36001 ttcggcacag gaattgtggc gggaaatacc ggtattctgc tgaataatca aatggatgat
    36061 ttttctgcta agcctggtgt acccaatgtt tatggcctag tgggcggcga tgctaacgcg
    36121 gtcgaaccaa aaaaacgtcc gctgtcgtcg atgtcgccga ctatcgtggt aaaagacggc
    36181 aaaacctggc tggtgaccgg tagccctggc gggagtcgaa tcatcactac tgtgctgcaa
    36241 atggtagtga acagcattga ttttggcatg aacgtcgccg aagcgaccaa cgcgccgcgt
    36301 ttccatcatc aatggttgcc ggacgaactg cgggtagaaa agggcttcag ccccgatacg
    36361 ctgaagttgc tggaacagaa agggcagaaa gtcgcgctga aagaagcgat gggcagcacc
    36421 caaagtatta tggttggacc ggatggcgaa ctgtacggtg cgtctgaccc gcgttccgtg
    36481 gatgatttaa cggcgggata ctgattttta attccaggcc cggtgtcaga caccgggcta
    36541 tttgcagatt atgccgtgag taatcgggct ggattatcaa tacaaagctt gcgcagagta
    36601 tcgttgtcta ctccgcgagc agccaaatag gcgaggaaaa cattcgggac aaacccccag
    36661 ccatttccgc catttttcgc ccacatctgt ttgagaaaaa catcatggct taaaacgatt
    36721 tggtcggcgt aacccagtgc aatcagattc gctactgcat ctgcggtctc ctgaacgccc
    36781 ggcgcgacac cttcttttgg aaaggtgatg tccagaccaa tcatgtcaaa ttcaagccat
    36841 acgccgcggt cgagcatttt acgttgatag acgacatctt ttcctgaagg gtccgaatgc
    36901 gccagcgaga cttttgccgg agagacgttc atttcttcca gcacgatatc cagcacctca
    36961 tcacccagtc gcagccaccc tggcatatgg atattcatcg ccgtgtgggg gttgttacat
    37021 tgtgccagag acgctgcccg caggctgtta cgctccgctt gggtaaacgc gggagatacg
    37081 ccgatttcac cgatcatgcc agcgcgaata tccgtctcgc caataccctg attcagttct
    37141 ttatcaatga gtgaggctaa cagctcaaca ggtttatgga tccgggtgct ttcaaatttc
    37201 tccagataag gcccggatga cgcaacgata ttcaaacccg tttttaaggc aacttctcgt
    37261 agcgctgagg catcccgtcc aatggattct gaaccggtgg cgtcgacaat cgtcctgccg
    37321 cccaaagaca taaagttatt gatttcgaag ataacatcat caatctcttt tctgtccatg
    37381 ttatcggcgc agcagtatgg gtcgtgtttc agcccccact gcaggtcagc actgactttc
    37441 tttcccacca gttgctgtga aaaagcataa tgtggctcgt ctacgaccga agacagatcg
    37501 ttaaacagat gttcatgcgg tagcgtcagc cccatatccg tatgcgccac cgggcctgtt
    37561 acggtttgca ggaaaccttt cattctgaca cctccatttt ttgcgccatt ttggatgctc
    37621 tgtattcagg gatggtggtc acaatcgcac cgactaacgc gaacagcgta ccgatgatgg
    37681 tgaccaggta gaccgtattg cctaatgaag ggatcaattc atcaattagc actgagccaa
    37741 gcagttggcc tgctgttgac gctacgccca gcatcaatag ccctaagcct ctcaccagaa
    37801 tcgccattag cccgatggat agcagaccca gcggaccacc gagatacatc caccatgtat
    37861 cgggtaactg gatggtgaca tggcctaatg cgatacgtat cgccagcgcc gcgcccagga
    37921 cacaaaagcc gacgatgaag ttccatgtaa tggacaccag catggagccc gttgcctcgg
    37981 cgactttcgc attccccgca ggctgccagc cagcgagtaa ccctgccaaa aaggggagga
    38041 tagcgagcag gataaacgag gttgagtgcc actgtggcga cacgacaaaa atggtggcga
    38101 taacggcgaa caatgcgcca gtaatgcgcc atggcgtaaa atattttttc tcctccacgc
    38161 cgatgccaaa acggtcgcac agcaggccgg aaagaagcag agcggaaatt aatgccgttt
    38221 gaaaggtggc aacgcccagc gcgctggcgg atgcgccttc agaaaatacg accatcgccc
    38281 cgcataatcc tgcaaaccaa ttccatagcg ggatttttct ctttttaatc agagtaggga
    38341 ttgaggcgaa ttgctggcgt gtttctttgc gcgcaataat aataaaaaac atgacgacca
    38401 gaccgctggc aaacgagatt actgcgcaag cattaccgtc ttgtaaccaa tgtcctaact
    38461 gcccattaac ggcagactgc atcggggaaa gcataccggc taagatggtg gcaagcatca
    38521 gtaagggggt tgagtactta ttcttgttca tacatcaatc cttatatttt ataaaaggag
    38581 taactttcgt tactccattg ttttttattt tctggcgatg aattgaagcg tgttgaccca
    38641 caggtcggta taaaatggcc atgacataaa ctgctgggtt ccccagtgtg gggagcagtc
    38701 actcataaag caggcggttt taccctgttg gtattcaccg aacactaaca atgggtcatt
    38761 atttattgtt aatacgacat cggcatcgtc tctggcgacg acctggttat atccaagaaa
    38821 taccgggtaa tctgagaacc cgttaacaac aggatgttca ggtgagacag cctcagcaca
    38881 aataccctct ggcttttcta cccggtcatc gccgtcaagc ataataactg gcagaacctc
    38941 agcaagaacg gtgttcttat aattggcttt tgcctcaata cccataaatg acagataacc
    39001 gccaatcatg agtagtccac cgccattttt gacgtactct ttaatggatt ccagagcgtt
    39061 tggttttatt tttagctgat agaaggtttc attttgtagc aggaaggtat tactaccaat
    39121 gtcgctaata acaatcacat cataacgatt taattcgtca atactctctg gaaaggcaat
    39181 ttgtaccgtg tgggcaggca tgtaatcaat atcaacgccg cctttcctca ggcattccag
    39241 taaccatgtc gcgccttctt catatttact ggaggtgaaa ctgtcataac cttttgaatg
    39301 aatcatatga atatgccagg attctccaat aaagagcacc tttagttttt tctgcgtatt
    39361 gttcatagtc tgctccttga tttagtgagt agagatagtt tgtttgtaat gtgaaccctg
    39421 aatacgatga agaacggagt cgttttccgg catatcagag gcattaggcg tttcaaccgc
    39481 aagtgaggca aatgcgctgg cgtagcacaa tgcggatgcc agtgactttc cttttgcaag
    39541 gccagatgag agggcgccat tgaaagcgtc acccgctccc gccgtatttt ttacaactgc
    39601 cggaaatgcc ggggaataga tgaattgtgt gccgtcataa gcaagcgaac ctttgctacc
    39661 taatgtaata atggtatttt tgacgccttt ctggtgaata attttggccg cgcatttggc
    39721 tgattcgata tcattaaccg ccatattggc cagcaggccg gcttccgttt catttggcgt
    39781 aatatagtca atgttatcaa tgatggtgtt aaccatgtca ttgtacggcg ctggattgat
    39841 gatgaccggt atgtcatttt tttgtgcgag acgaattgtt tgctgcagcg cttcgtaatt
    39901 cgtctccagt tggacaagaa caatatctga atgaacaatg gcttcttttt gaatggtgat
    39961 ttcatcaggg gaaattgtca tgttggcgcc agggtagata gcgatgacat tatctccggt
    40021 atcaccattc accatgatgg ttgctgtacc tgtttgtgtt tctttggtct ggtagataac
    40081 acttttatgg atttttgatg agtttataaa attaatggcg taatcgctaa aatgatctga
    40141 gccgacttta gtaataaaat gcacatcaga atcggcatag cttgctgcta atgcctgatt
    40201 acatccctta ccgccgggtg aaaaaataaa tttatcggcc agcaatgatt ctcccgttga
    40261 gggtaatctc ggtagataac tgataatatc aacattgaac gagccaataa cacatacatt
    40321 atttttcatg gcagagagac ctttttttat tttctgcgct gattcatatt tttccagcac
    40381 ataagcaatt tcattttttg cgacgttatc aagagaatca agggtaataa atgcaccacc
    40441 atgacagcga gtaagatatc cctgtccggc aagttcattg agatctgaac gaatagtttc
    40501 ctttgttacc ttgagacttt tcgccagatt tgaaactttt acaactcccg aaatactgag
    40561 ttccttcaat attctatgat ggcgttcaaa tttcattttt tacctcaccg tggttaaatt
    40621 agtcccggga ggagtatatt gttgtgattg tcaccataaa gtgatggcag aaaccaaaaa
    40681 aaaacaaaaa tgtaatatta atattgctaa aattacggaa aaaacggtga taaagcttaa
    40741 agtggtaata accatgaaat tcaagtggtt attgttttga tataggggaa gtaggctgca
    40801 ataactggaa tgttgtgaag gtttgtgacg tttcgcccca cagggtgggg cggggaagcg
    40861 ctatttcacg cgcgccataa agtacgtatc aacgtactca ccgttgcgca ggccgtattt
    40921 cttaccggtg ccttcgattt caaagccgta cttcttatac accgccaccg cgggctcgtt
    40981 atcaacaaac accgttaact caatacgctc gacgcgcagc cagttgtcac acatgtcgat
    41041 catcgtgcgg atcagcgcgc tggcaatgcc gcgattgtgc caccgggcat ccacgcagat
    41101 accaaaatcg gccacgtggc tgcgacgggg acgttgggtg acctgaatag aaagatggcc
    41161 aacgacaata tcgtcaatgc aggcaaccag ttgtttaacc ccggcttgct cggttagccg
    41221 cgcctgccac atttcgaggg aaggatgagg aacctgtagc gtgttgtggt acacctccgg
    41281 ctgggcgtgg atctgacgaa tggcgtcgta atctttcggt tcagcgtggc gtatcactat
    41341 ttcactcatt ccttatctcc tgcagggtta attgtgtatt tacactcgct gagaaagaaa
    41401 attccgtcaa ccgcattttt ttgcaaaaag aagtagacaa gtgcgaatga gaatgattat
    41461 tattgccttg cattcagggg aacccctacg gataacctga aagcatgaca ttgctcacat
    41521 tgcttccagt tttattttgg ccagcttttg ctggcttttt ttttggtttt gtttcagcct
    41581 ggcttacttg tcattttgtc cccgggaagt gctcgtgctc ctcacgtaca tttagtacgc
    41641 tccgggccct gcgcgcttgc cgtgaacaaa ctgaccgcga cgctgacggc cgatcttgag
    41701 gcatctgctt ttgtaggccc gaaaaggctt ctccgccacc gtcaaagaat ccaacattca
    41761 gtctcctcac gctttgcgct atggtgtaaa caatcatctt caaaaggatc gtctcatgac
    41821 cttacactgc gcatttattg gattcggcaa aagtaccacc cgttaccatc tcccctacgt
    41881 tctgaatcgt aaagatacct ggcatgtcgc gcatattttc cgtcgtcacg ctaaaccgga
    41941 agagcaggcg ccgcagtatt cgcatattca cttcaccagc gatctggatg aggtgttggg
    42001 cgatccgcag gtaaaactgg tgatcgtctg tacgcatgct gacagccatt tcgaatacgc
    42061 caaacgcgcg ctggaagcgg gtaaaaatgt gctggttgag aaacctttca cgccgacgct
    42121 ggcggaggca aaagtgttgt tcgaactggc gcgaagcaaa ggactgaccg tcacgccata
    42181 tcagaatcgg cgttttgatt cctgttttct cactgctaaa aaagcgattg agagcgggaa
    42241 actgggcaag attgtcgaaa ttgaaagcca tttcgattat taccgcccgg tagcagaaac
    42301 caaaccgggc ctgccgcagg atggcgcatt ctatggactt ggcgtccaca ctatggatca
    42361 aattatttcg ctatttggcc gcccggatca tgtcgcgtat gacattcgta gcctgcgtaa
    42421 taaagcgaat ccggatgaca cctttgaagc gcaattgttc tacggtgccc tgaaagccat
    42481 tgtgaaaacc agccatctgg tgaaaatcga ctatccgaag tttattgttc acggcaccaa
    42541 aggttcgttt gtgaaatacg gtatcgatca acaagaaacc agcctgaaag cgaacattat
    42601 gcctggcgag ccgggttttg ccgctgacga atccgtcggt gtgctggaat atgttaacga
    42661 tgaaggcgtt acggtgaaag aagaggtgaa accggaaacg ggtgactatg gtcgcgtcta
    42721 tgatgcgctg taccagacgt tgaccatcgg tacgcctaat tatgtcaagg aatctgaagt
    42781 tcttaccaat ctggaaatcc tcgaacgtgc cttcgaacag gcaacgcctg cgacgataac
    42841 cctcgctaaa tagcccttac agactcctct gcgcttattc atattttttg aacagaggag
    42901 tcaattttca ccctctatga tcccggacgg aatgagtcca cacttattcc atcgaaaaca
    42961 tctgggggtg aacacaatga tctacttacg caaagcaaac gaccgcggtc atgcgaatca
    43021 tggctggctt gactcctggc ataccttttc ttttgccgat tattacgatc cgaactttat
    43081 ggggttctcg gcgctacgtg tgattaacga cgatgtgatc gacgcaggcc agggtttcgg
    43141 cacgcatccg cataaagaca tggaaatttt gacctatgtg ctggaaggtg ctgtagaaca
    43201 ccaggacagt atgggcaata aagaacaggt tccggcaggt gaattccaga ttatgagcgc
    43261 cgggaccggc gttcgccact ccgagtacaa cccgagcaaa acggatcgtc tgcggctgta
    43321 ccagatctgg atcattccgc aagaaacagg catcacgccg cgctacgaac agcgccgctt
    43381 cgacgccgcg cagggcaagc aactggtgct ttcgccagat gctcgcgatg gttcgctgaa
    43441 ggtccaccag gatatggagc tgtaccgctg ggcgctgctc aaagatgagc aatcggtgca
    43501 tcagattgcc gccgagcgcc gcgtctggat acaggtggta aaaggtaacg tgaccattaa
    43561 cggtaccaaa gcgacgacca gcgacggcct ggcgatttgg gatgagcagg caatctcgat
    43621 tcatgccgac agcgacagtg aagtgttact gtttgacctg ccgccagtct aaaaatacac
    43681 gtcatccttc aagctgcatc tgtgttggct ttattactcg gcccatccat aggcctcgcc
    43741 ccttcggggc cgctgcgagc agcgttcaaa tctgctcccg gcagatttgt cgctcacccc
    43801 ggtcgcgtac ttaatgtacg ctcccgggga tttactgagg gacatccttg tccctcacca
    43861 gaggcaacct tcggttgttc aaattcgttc ctgacgaatt tgtcactgcg tcgccgcctt
    43921 gatgcaactc gaatgatttt gtgtatttct cataataaaa aactcctttt tctctgcgaa
    43981 ggttcacgca cgtccgtggt aaactgggga aatctatccc tttttaacgc ttcaggacga
    44041 tgaaaaagaa aagacccgta cttcaggatg tagccgaccg cgtgggcgtg accaaaatga
    44101 cggtcagccg ctttttgcgt aacccggagc aggtctccgt ggcgctgcgg ggcaaaattg
    44161 ccgctgcact tgatgagctg ggttatattc ccaatcgcgc tcctgatatc ctttctaacg
    44221 ccaccagtcg cgctatcggc gtgctgttac cgtctctcac caaccaggtc tttgcggaag
    44281 tgttacgcgg cattgaggcc gtcaccgatg cccacgggta tcagaccatg ctggcgcact
    44341 acggctataa accggagatg gagcaggagc gcctggaatc gatgctctcc tggaatatcg
    44401 acggtcttat cctcacagaa cgtacccata cgccgcgcac cttaaaaatg atcgaagtcg
    44461 ccgggattcc ggtggtggaa ctgatggaca gccagtcgcc gtgtctcgat attgccgttg
    44521 gttttgacaa cttcgaggcc gcccgtcaga tgaccgccgc gattatcgcg cgtggtcatc
    44581 gtcatatcgc ctatctgggg gcgcgcctcg acgaacgtac tatcatcaag cagaagggct
    44641 atgaacaggc gatgcgggac gccggcctgg ttccttacag tgtgatgatg gagcaatctt
    44701 catcctactc ttccggtatc gaactcatgc gccaggcgcg acgcgaatac ccacagcttg
    44761 acggtatttt ttgcaccaac gatgacctgg cggtgggggc ggccttcgaa tgccagcgcc
    44821 tggggctaaa aatcccggac gacatggcga tcgccgggtt ccacggtcat gacatcggcc
    44881 aggtgatgga accgcgtctg gcaagcgtcc tgacgccgcg cgagcgaatg ggcagcattg
    44941 gcgcggaacg tctgttggcc cgcattcgcg gcgaaacggt cacgccgaaa atgttagatt
    45001 taggtttcac cttgtcaccg ggcggatcta tttagtctga caactttgaa gtagctcaca
    45061 cttattcact tttggcacga atggtcattg cgtcgtgaat ggtgcggttg gacaatgtta
    45121 ccgataacag ttacccgtaa caaattttgc aacttgtaga gtggggtccc gctttgagca
    45181 cgactaatca tgatcaccac gtttacgttc tgatgggcgt atcaggcagc ggtaaatccg
    45241 ctgtcgcaag cgccgtggcg catcagcttc atgccgcgtt tctggacggc gattttctgc
    45301 atccgcgctg caatattgaa aaaatggctt ccggcgagcc gttgaatgat gatgaccgca
    45361 aaccgtggtt gcaggcgctg aacgacgccg ctttcgcgat gcagcgtacc aataaaatct
    45421 cgctgattgt ctgttccgca ctgaaaaaac actatcgcga cctgctgcgc gagggaaacc
    45481 cgaatctctc ctttatctat ctgaaaggtg atttcgacgt cattgaaagc cgtctgaaag
    45541 cgcgcaaagg tcatttcttc aaaacccaga tgctggtgac gcagtttgaa acgctgcaag
    45601 agccgggtgc cgacgaacgc gatgttctgg tggtggatat cgaccagccg ctggaaggcg
    45661 ttgtggcgag caccattgag gtcatcaata aaggcagtac gctgtgagta cattaacact
    45721 ggttttaacc gccgtcggtt ccgtcttact gctgctgttt ctcgtgatga aggcgcgtat
    45781 gcacgccttc gtcgcgttaa tggtcgtctc aatgggcgcg gggctttttt cagggatgcc
    45841 gcttgataaa atcgccgcga ccatggaaaa agggatgggc ggcacgctgg gcttcctggc
    45901 gattgtggtc gcgctggggg cgatgttcgg taaaattctg catgaaaccg gcgcggtcga
    45961 tcagatagcc gtgaaaatgc ttaaatcctt tggccataac cgcgcgcact atgcgattgg
    46021 ccttgccggg ctgatttgcg cgctcccgct attctttgaa gtggcgattg tgctgctgat
    46081 aagtgtggcg ttctctatgg cgcgtcatac cggcacaaac ctggtgaagc tggtcattcc
    46141 gctgtttgcg ggcgtggcgg cagccgcggc gtttttgttg cctgggcctg cgccgatgct
    46201 gctggcttcc cagatgcatg ctgatttcgg ctggatgatc ctgattgggc tgtgcgccgc
    46261 cattcctggc atgattatcg ccgggccgct gtgggggaat tttatcagcc gttacgttga
    46321 gctgcgtatt cctgacgaca ttaccgagcc gcatctgggc gaaggcaaaa tgccttcttt
    46381 cggcttcagc ctgtcgctga tcctgctgcc gttggtgctg gtaggactga aaacgatcgc
    46441 cgcgcgcttt gtgccggaag gttccaccgc ttatgaatgg tttgagttta tcggccaccc
    46501 cttcactgcg attctggtcg cttgtctggt agcgatttac ggcctggcga tgcgccaggg
    46561 gatgccgaaa gacaaagtga tggaaatctg cggccacgcg ctacaaccgg cgggcattat
    46621 tctgctggtg attggcgcag gcggggtgtt caaacaggta ctggttgact ccggcgtcgg
    46681 cccggcgctg ggcgaagcgt taaccggtat gggactgccg attgccatta cctgctttgt
    46741 gctggcggcg gcggtgcgca tcattcaggg ttccgcgacc gtggcgtgtt taaccgcggt
    46801 cggtctggtg atgccggtca ttgagcaact gaatttctcc ggcgcgcaga tggcggcgct
    46861 ctctatctgt atcgccggcg gttcaattgt ggtttctcat gttaacgacg ctggcttctg
    46921 gctgttcggt aaatttaccg gcgcgaccga agcgcagacg ctgaagacct ggacgatgat
    46981 ggaaactatc ctcggcacgg tcggcgcgat tgtcgggatg attgctttcc aactgctgag
    47041 ctgagtcttg ttgcccggtg gcgctgtgct taccgggcct ggaaacgggc acatatcgat
    47101 accgtaagcc gggtaaggcg taatcgctac ccggtttttt tattgaggtg tgcatggcaa
    47161 tcgcccaacg acattttgcc tcgccatgtt tcagtacgcg cataaaagca ggcaaatttc
    47221 tacgctgatc cataattagg atcaataaaa cagcgacgga aatgattccc ttcctaacgc
    47281 aaattccctg ataatcgcca ctggactttc tgcttgcgcg gtaaggcagg ataagtcgca
    47341 ttactgatgg cttcgctatc attgattaat ttcacttgcg actttggctg ctttttgtat
    47401 ggtgaaggat gcgccacagg atactggcgc gcatacacag cacatctctt tgcaggaaaa
    47461 aacgctatga aaaatgttgg ttttatcggc tggcgcggaa tggtcggctc tgttctcatg
    47521 caacgcatgg tagaggagcg cgatttcgac gctattcgcc ctgttttctt ttctacctcc
    47581 cagtttggac aggcggcgcc caccttcggc gacacctcca ccggcacgct acaggacgct
    47641 tttgatctgg atgcgctaaa agcgctcgat atcatcgtga cctgccaggg cggcgattat
    47701 accaacgaaa tttatccaaa gctgcgcgaa agcggatggc agggttactg gattgacgcg
    47761 gcttctacgc tgcgcatgaa agatgatgcc attattattc tcgacccggt caaccaggac
    47821 gtgattaccg acggactgaa caatggcgtg aagacctttg tgggcggtaa ctgtaccgtt
    47881 agcctgatgt tgatgtcgct gggcggtctc tttgcccata atctcgttga ctgggtatcc
    47941 gtcgcgacct atcaggccgc ctccggcggc ggcgcgcgcc atatgcgcga gctgttaacc
    48001 caaatggggc agttgtatgg ccatgtcgcc gatgaactgg cgacgccgtc ttccgcaatt
    48061 cttgatattg aacgcaaagt tacggcattg acccgcagcg gcgagctgcc ggtggataac
    48121 tttggcgtac cgctggcggg aagcctgatc ccctggatcg acaaacagct tgataacggc
    48181 caaagccgcg aagagtggaa aggccaggcg gaaaccaaca agatcctcaa tactgcctct
    48241 gtgatcccgg ttgatggttt gtgcgtgcgc gtcggcgcgc tgcgctgtca cagccaggcg
    48301 ttcaccatta agctgaaaaa agaggtatcc attccgacgg tggaagaact gctggcggca
    48361 cataatccgt gggcgaaagt ggtgccgaac gatcgtgata tcactatgcg cgaattaacc
    48421 ccggcggcgg tgaccggcac gttgactacg ccggttggtc gtctgcgtaa gctgaacatg
    48481 gggccagagt tcttgtcggc gtttaccgta ggcgaccagt tgttatgggg cgccgccgag
    48541 ccgctgcgtc gaatgctgcg ccagttggcg tagtggctat tgcagcgctt atcgggcctg
    48601 cgtgtggttc tgtaggccgg ataaggcgtg tcagcgccgc catccggcaa tatccgccag
    48661 ataaggcgta gtcggcaagc agacgtcaga ttgatatgta gggtgcatcg tcaccttttt
    48721 ttgcgtaata caggagtaaa cgcagatgtt tcatttttat caggagttaa gcagagcatt
    48781 ggctattctt taagggtagc ttaatcccac gggtattaag cctaacctga aggtaggacg
    48841 acgcagatag gatgcacagt gtgctgcgcc gttcaggtca aagaagtgtc actacctgat
    48901 gttgaattca gtgagatgga gtgacgccac aaaacaggat aacaaaccat gtccagtcgt
    48961 atcgatagag acgtgattaa tgcgctaatt gcaggacatt ttgcggaccc tttttccgta
    49021 ctcggaatgc accagaccca agccggacta gaagtccgcg ccctattacc tgacgccacc
    49081 gacgtatggg tgattgaacc caaaaccgga cgtaaagtcg gcaaactgga atgtctcgac
    49141 gctcgcggtt ttttctgcgg cgttttaccc cgacgtaaaa atttctttcg ctatcagctc
    49201 gccgtgacct ggcacggaca gcagaacctc atcgacgatc cttaccgttt tggtccatta
    49261 atacaggaaa tggatgcctg gctattgtcg gaaggcaccc acctgcgtcc ttatgaaacg
    49321 ctgggcgcgc acgccgatac gatggatggc gtcaccggca cccgtttctc cgtctgggcg
    49381 cctaatgccc gtcgcgtttc ggttgtcggg caattcaact attgggatgg gcgtcgccac
    49441 ccgatgcgtc tgcgcaaaga gagcggtatt tgggagctgt ttatccccgg cgcgcataat
    49501 ggacaactgt ataaattcga gctgcttgat gcgaacggta atctgcgcat taaagccgat
    49561 ccctatgctt ttgaggcgca gatgcgtccg gaaacggcgt cgatgatttg cggactgccg
    49621 gagaaagtga cgccaagcga agaacgacaa aaagccaatc agtttgatgc gccgatctcg
    49681 atttatgagg tgcatttagg ttcatggcgc cgccatacgg ataacaattt ctggctgagc
    49741 tatcgtgagc tggcggatca gcttgtgcct tacgccaaat ggatgggctt tacgcacctt
    49801 gaactcttgc cggttaacga acatccgttt gacggcagtt ggggctacca gccgaccggc
    49861 ctctacgcgc cgacccgccg ctttggtacg cgggacgact tccgctattt catcaatgcg
    49921 gcccatgcgg cgggccttaa cgtcattctc gactgggtgc cgggccattt cccgtccgat
    49981 gaatttagcc tcgcggagtt tgacggcacc cacctctatg agcatagcga cccgcgcgag
    50041 ggctatcacc aggactggaa tacgctgatc tacaactatg gtcgtcgtga agtcagtaat
    50101 tatctggtgg gtaacgccct gtactggatg gagcgttttg ggattgatgc gctgcgtgtc
    50161 gatgcggtgg cctctatgat ctaccgcgac tacagccgca aagagggcga gtggataccg
    50221 aacgagttcg gcggtcgtga aaacctggaa gccattgagt ttctgcgtaa taccaaccgc
    50281 attattggcg agcaggtgcc cggcgcggtc agcatggcgg aagagtcgac agacttctct
    50341 ggcgtgacgc gtccaccgga aacgggtggg ctggggttct ggtacaagtg gaatctgggc
    50401 tggatgcacg acacgctgga ctacatgaag ctggacccgg tgtaccgcca gtatcatcac
    50461 gacaagctga cctttggtat gttgtacaac cataccgaaa actttgttct gccgctgtcg
    50521 cacgatgagg tggttcacgg caagaaatcc attctcgatc gtatgccggg cgatgcgtgg
    50581 caaaaattcg ccaacctgcg cgcctattat ggctggatgt gggccttccc cggcaagaaa
    50641 ctgctgttta tggggaatga gtttgcccag ggacgcgagt ggaaccatga cgccagcctc
    50701 gactggcacc tgctggaggg gggcgataac tggcaccacg gggttcagcg tctggtgcgc
    50761 gatctcaacc acacctatcg ccaccataaa gcgttgcatg agctggattt cgatgcttac
    50821 ggctttgagt ggctggtggt cgatgacaat gaacgctcag tactgatttt tgtacgccgt
    50881 gataaagccg gtaacgagat catcgtcgcc agcaacttta cgcccgttcc tcgccacgac
    50941 taccgctttg gcatcaacca gccgggacgc tggcgtgaaa ttctcaatac tgattcgatg
    51001 cattatcacg gtagcaacac cggcaatggc ggtgtggtgc acagcgatga gatcgaaagc
    51061 catggccgtc agcactctct taacctgacg ttaccgccgt tggcgacgat ctggctgatg
    51121 cgggaggggg aatgacgcag cttgcgatcg gcgaagcaac gccgcatggc gcaacgtatg
    51181 acggtcatgg cgtgaatttc acgctctttt ccgcccatgc ggagcgcgta gagctgtgcg
    51241 tttttgattc ccgagggaat gagcgtcgct atgacctgcc aggacgtcgc ggcgatgtct
    51301 ggcatggtta tctggcaggc gccaggccag gtttgcgcta tggctatcgc gtacatggcc
    51361 cgtggcagcc agcgcagggg catcggttta atccggcgaa gttactgctt gacccttatg
    51421 cgcgccaagt cgagggcgaa ctaaaagatc atccgctgtt gcacggcgga cacgatgaac
    51481 cggactaccg cgataacgcg gcggtggcgc cgaaaagcgt ggtaatcagc gaccattatg
    51541 actgggaaga tgacgccgcg ccgcgcacgc cgtggggaaa aacggtcatc tatgaagcgc
    51601 atgtcaaagg gcttacctat ctgcatccgg aactccccca ggagatacgc ggcacctata
    51661 aagcgctcgg tcatccggtc atggtggcgt acttcaaaca gcttggcatt acggcgctgg
    51721 aactgttgcc ggtggcgcag tttgccagcg agccgcgtct gcaacgtatg gggctgacca
    51781 attattgggg ttataaccca atggcgatgt ttgcgctgca tcccgcctgg gccagttcgc
    51841 ccgagacggc gctggacgag tttcgcgatg cggtgaaagc gctgcatcgc gcggggattg
    51901 aggtcattct ggacatcgta ttaaaccata gcgccgagct ggatctggac ggtccaacct
    51961 tctccctgcg cggaattgat aaccgtagct attattggat aagggacgat ggcgattatc
    52021 acaactggac ggggtgcggc aacacgctca atttaagcca tcccggcgtg gtggaatacg
    52081 cgtgcgagtg tttgcgctat tggatggaaa cctgtcatgt cgatggtttt cgttttgatt
    52141 tggcgtccgt catggggcgc acgccgacgt ttcgccagga tgcgccgctg ttcgccgcga
    52201 ttaaagcgtg tcctgtgtta tcaacggtca agctgattgc tgaaccgtgg gatattggcg
    52261 agggcggcta tcaggtcggg aattttccgc caccgtttgc cgagtggaac gatcattttc
    52321 gcgatgcggc ccgccgattc tggttgccgc gtaacctgac gaccggggag tttgcctgtc
    52381 gtttcgccgc ttccagcgat gtgtttaaac gcaatggccg cgcgcccggc gcctctgtca
    52441 atctgctcac ggcgcatgac ggttttacgc tccgggactg cgtctgtttc aatcagaaac
    52501 acaatgaggc gaacggtgag gaaaatcgcg acggcaccaa cagcaattac agcgacaatc
    52561 atggtaaaga aggattaggc ggtccgcttg atttaatgga gcggcggcgc gacagcattc
    52621 atgccctgct ggcgacgcta ctgctctctc agggaacgcc gatgctgctg gcaggcgatg
    52681 aacacggcca tagccagcac ggcaacaata acgcctactg tcaggataat gccttaacct
    52741 ggctggactg gcagcaggca aatcgtgggt taaccacgtt taccgccgcg ctgattcgtt
    52801 tgcgtcagca gataccggct ttaaccggca atagctggtg ggaagaaggc gatggcaacg
    52861 tgcgttggct aaataaaaac gcgcaaccct tgagtgcgga tgagtggcaa aacggaccta
    52921 agctgatgca aattctgttg tcggaccgtt ttctgattgc gataaatgcc acgcttgagg
    52981 tgacagatat agttttaccc gaaggggaat ggcgcgccgt tcccccattc gctggagagg
    53041 ataatccggt gataacggcg gtctggcagg gactgtgtgt gttccagaga ggataaaaaa
    53101 ggagttaatc atggtgagtt tagagaagaa cgatcgtgta atgttggcgc gccagctgcc
    53161 attgaaatct gttgccctaa tcctggccgg cggccgcggc acgcgtctaa aagatttaac
    53221 gaacaaacgc gccaaaccag ccgtccactt tggtgggaag ttccgcatca tcgatttcgc
    53281 cttatctaat tgtctgaact ccgggattcg ccgtatcggc gtgatcactc agtatcagtc
    53341 ccacacgctg gtgcagcata ttcagcgcgg ctggtcactg tttagcgaag agatgaacga
    53401 atttgtcgat ctgctgccag cccaacagcg tatgaagggc gaaaactggt atcgcggcac
    53461 ggcagacgcg gtgacccaga acctggatat tattcgttgc tataaagcgg aatatgtcgt
    53521 catcctggca ggcgatcata tctacaagca ggactactcg cgtatgttga tcgatcacgt
    53581 tgaaaagggc gcgcgttgca cggtggcctg tatgccggtg ccgatcaaag aagcgacggc
    53641 gttcggcgtg atggcggtcg atgaaaacga caagattatt gattttgtcg aaaaaccggc
    53701 gaatcccccc gcaatgcctg gtgacgccag caaatcgctg gccagtatgg gcatttacgt
    53761 ttttgacgcc gattacctgt atgaattgtt ggcggcagac gataaagatg acgcttccag
    53821 ccacgatttc ggtaaagaca ttatccccaa aatcacccgc gaaggtatgg cttacgcgca
    53881 tcctttcccg ctctcctgcg tgcagtccga tccacaagcc gaaccgtact ggcgtgatgt
    53941 aggtacgctg gaagcttact ggaaggcgaa cctggattta gcctcggtga cgccggagct
    54001 ggatatgtat gaccagaact ggcctatccg tacgcatatg gaatcgctac cgcctgcgaa
    54061 attcgtgcag gaccgctccg gtagccacgg tatgacgctg aactcgctgg tctccggcgg
    54121 ctgcattatc tctggttcgg tggtggtgca atctgtgctc ttcccacggg tgagaataaa
    54181 ttctttttgt aatattgatt cggcagtgtt gttacctgag gtttgggtag ggcgctcctg
    54241 ccgtttacgt cgctgtgtta ttgaccgtgc ctgtattatc ccggaaggca tggtgattgg
    54301 tgaaaatgcg gaagaggacg ctcgtcgttt ctaccgttca gaagaaggta ttgtactggt
    54361 cacgcgtgaa atgctgcgca aactgcaggt caaacaggag cgataatgca ggttttacat
    54421 gtatgttcag agatgttccc cctgctgaag actggggggc tggcggatgt gataggcgcg
    54481 ttgcctgcgg cacaaattgc ggatggtgtt gatgttcgcg ttctgcttcc tgggtttccc
    54541 gatatccgtc gggggatacc cgatgcgcat gtggtgagcc gccgcgatac tttcgcaggt
    54601 aagatatcgc tgctgttcgg gcattataac ggcgtgggca tttatctgat cgacgcgccg
    54661 catctgtacg agcgtccagg cagtccctat cacgatacga atttatatgc ctatatcgat
    54721 aacgtgctgc gctttgccct gttagggtgg gtcggctgtg aaatggcctg cggacttgat
    54781 ccattctggc gccccgacgt ggtgcacgcc catgactggc acgccgggct ggcgcccgcc
    54841 tatctggcgg cgcgcgggcg gccggcgaaa tcggtcttta ccgtacacaa cctggcctat
    54901 caaggcatgt tttatgcaaa gcatatggat gacatcgagc tgccgtggtc attctttaat
    54961 atgcatgggc tggagttcaa cggacaactc tcctttttga aggccggttt gtactatgcc
    55021 gaccatatta cggcggtgag cccgacctat gcgcgtgaaa ttaccgaacc gcagtttgct
    55081 tatggtatgg aaggcctgtt gcgtcagcgt catctggaag ggcgcttgtc cggcatactg
    55141 aacggcgtgg atgagaagat ctggaacccg gaatccgatc tgctgctggc gtcgcgctac
    55201 acgcgcgata ccctggaaga gaaggcggaa aacaaacgtc agctacaaat tgcgatgggg
    55261 ttgaaggtta acgacaaagt gccgctgttc gccgtggtaa gccgtctgac caaccagaaa
    55321 ggtctggatc tggtgctgga ggcgttaccg gggctgctgg agcagggcgg ccagttggcg
    55381 ctacttggcg cgggcgatcc ggtgcttcag gaggggttcc tcgcggcggc ggcggaacac
    55441 ccagggcagg ctggcgtaca gatcggctat cacgaagctt tctcgcatcg cattatgggc
    55501 ggcgcggacg ttattctggt gcccagtcgt ttcgaaccgt gcggcttaac gcagttatat
    55561 ggcttaaagt atggcacgct gcctctggtg cggcgtaccg gggggttggc cgatacggtc
    55621 tccgacagtt cgctggaaaa tctggcggac ggtatcgcca gcggttttgt ctttgaagac
    55681 agtaatgcct ggtcgttgct acgcgcgatt cggcgtgctt ttgtgttgtg gtcacggcct
    55741 tcgctttggc ggtttgtaca acggcaggcg atggcgatgg attttagctg gcaagttgcc
    55801 gcgaaatcat accgcgagct gtactatcgc ttgaaatagt catccaggaa tcatttatat
    55861 gaatgctccg tttacttatg catcgcccac actcagcgtt gaggcgctta agcattctat
    55921 tgcctataag ctgatgttta cgattggtaa agacccggtc attgccaata aacacgaatg
    55981 gctgaacgcc acgttgttcg cggtgcgcga tcgtctggtg gagcgctggc tgcgttctaa
    56041 tcgagcccaa ttatcgcagg aaacccggca ggtttattac ctgtcgatgg agtttttgat
    56101 tggtcgtact ctctctaacg cgctgctctc gctgggcatt tatgacgacg ttaaaggcgc
    56161 gctggaggcc atgggcttag atctcgaaga gctgatcgat gaagagaatg acccagggct
    56221 tggcaacggc ggcttaggac ggctggcggc ttgcttcctg gactcgctgg cgacgctagg
    56281 attaccgggt cgcgggtatg gcattcgcta cgactacggc atgtttaagc agaatattgt
    56341 cgacgggcgg caaaaagaat ctccggatta ctggctggaa tatggcaacc cgtgggagtt
    56401 caagcgccac aatacgcgct ataaggtgct ttttggcggg cgcattcagc aggaaggtaa
    56461 aaaagcgcgc tggattgaga cggaagagat tctggccgtc gcgtatgatc agatcatccc
    56521 cggttacgac accgacgcca ctaacacact gcggctgtgg aatgcgcagg ccagtagtga
    56581 aatcaacctc ggtaaattca accagggcga ctactttgcg gcggtggaag ataaaaacca
    56641 ctctgagaac gtttcacggg tgctctaccc ggacgattcc acctattccg gacgcgagct
    56701 acgcctgcgc caggagtatt ttctggtctc ggcgacggta caggatatcc tgcaccgtca
    56761 ttatcaactg cataaaacct atgagaatct ggcggataaa atcgccattc acctcaatga
    56821 tacgcatccg gtgctgtcaa ttccggagct gatgcgcctg ctgattgatg aacataaatt
    56881 tagctgggac gacgcgtttg aggtgtgctg tcaggtcttc tcttatacca accatacgtt
    56941 gatgagcgag gcgctggaaa cctggcccgt cgatatgctg gggaaaattc tgccccgtca
    57001 cctgcagatt atcttcgaga ttaacgacta tttcctgaaa acgttgcagg agcaatatcc
    57061 caacgatacc agcctgcttg gacgcgcgtc gattattgat gagtcgaacg gtcgccgggt
    57121 acggatggcc tggctggcgg tggtagtcag ccataaagtc aacggcgttt ctgaactcca
    57181 ttccaacctg atggtgcagt cgctgttcgc ggattttgcg aagattttcc cgacccgttt
    57241 ttgtaacgtc acgaacggcg ttacgccgcg ccgctggctg gcgctggcaa acccgccgct
    57301 ttctgacgtg ctggatgaga atattggtcg tacctggcgt accgatctta gtcagctcag
    57361 cgagctgaag cagcattgtg attatccgct ggtcaatcat gcggtgcgtc aggcgaagct
    57421 ggaaaataaa aagcggctgg cggtagtgat agcgcaacaa ctgaatgtgg tggtgaaccc
    57481 taaagcgtta ttcgacgtgc agattaagcg tattcacgaa tacaagcggc agttgatgaa
    57541 cgtactgcat gtcattaccc gctataaccg cattaaagaa aatccggagg ccgactgggt
    57601 gccgcgggtg aatatttttg ccggtaaggc ggcttccgcc tattacatgg caaaacatat
    57661 cattcatctg atcaacgacg tggcgaaagt gattaacaac gatccgcaga ttggcgacaa
    57721 gctgaaagta gtgtttatcc cgaactacag tgtcagtctg gcgcaggtga tcattcccgc
    57781 tgccgacctg tctgagcaga tttcgctggc agggacagaa gcttccggca ccagtaatat
    57841 gaaatttgcc ctgaacggcg cgctcaccat tggtacgctg gatggcgcga acgtagagat
    57901 gcaggagcat gtcggcgagg agaatatctt tatcttcggt aatactgcag aagaggtgga
    57961 agcgttgcgc agacagggtt ataagcctcg cgactattat gaaaaagatg aagagctaca
    58021 tcaggtactg acgcagattg gtaacggcgt ctttaatccg gaagagccag gccgttaccg
    58081 cgatctggta gattcgctga ttaactttgg cgatcactat caggtgctgg cggactaccg
    58141 cagctacgtg gactgccagg ataaggtgga tgagttgtat cgtcgcccgg aagagtggac
    58201 gacgaaagcg atgctcaaca ttgccaatat gggctacttc tcatcggaca gaaccatcaa
    58261 agagtatgcc gaaaatatct ggcatattga tccggtgcgg ttgtaaatcc cgatgccgac
    58321 ggcgcttcgc ttgcccggcc tacgtttatg tatccttgta ggccggatca ggcgttagcc
    58381 gccatccggc atttttctca ggacgccagt gaaagttggt gtttctcaac atacgccgcc
    58441 agccactggg tgatgcggga ctgctgctcg gcggtcagcc acatgccttc tttggtgcga
    58501 cgccagatag cgtcttcagt acggcgcacc cattcgtgat ccaccaagta tttgagttcc
    58561 gcttcgtaaa actcatgacc gaaatcttcg cctaaatcaa gcagtgacgt ggcttcgccg
    58621 agaatccact ccgtgttgct gccgtaagtg cgcgaatagt ggcgcgccag cgattccgtc
    58681 aggaacggat aacgacgacg cagcttcgcc gcgtaatctt cgcggctgcc gtcgatgtcg
    58741 ccgccgggca gtacgcacgt tttggtccat gccggcccga tgcctggata ataagacgcc
    58801 agtttttcca tcgcatgttc ggccagctta cggtaggtcg tgagcttacc gccaaacacg
    58861 gaaagcagcg gcgctttgcc gttttcatca tggatatcaa gggtataatc gcgagtgatc
    58921 gcctgcggcg agtcggactc atcatcgcac agcggacgga caccggagta cgtccagacg
    58981 atgtcatcgc gccccagttg tttctggaag tgcgcgttat agaccttcaa caggtaatta
    59041 atttcgctct cttcaatttt taccgctttc ggatcgcctt tatattcgac atcggttgtg
    59101 ccaatgatcg aaaactcttc catccacgga atgacaaaga cgatacgctt atcttcgttt
    59161 tgcagaatat acgcctgttt ctgattatgg acgcgcggca cgacgatatg gctgcctttg
    59221 atcaggcgga tgccatacgg cgacggcagg tgcatccctt cgtcgaagaa ctgtttgacc
    59281 cacgggccgg tggcgttaac cagtccgcgc gcctgccaga catatttttt accggtgtcg
    59341 atatcttccg cttcgacaat ccacaggcca ttttcccgac gagcggcggt tgcgcgagta
    59401 cgggtaagga cttcgccgcc tttacgcacc accatctgtg cgttggccag taccagacgc
    59461 gcatcgtcta cccagcagtc ggagtattcg aatccgcgca cgatttcagg tttgagtacc
    59521 gaatctgcgc caaaccgcac accggtggaa ccgggtaaac tggtacgttt gccgaggtga
    59581 tcgtacataa acagaccgat acggatcatc caggctggac gtaagtgcgg gcggtgcggc
    59641 agacgaaaac gcatcgggaa ggcgatgtgc ggcgccattt tcaacagcac ttcacgttcg
    59701 gccagcgctt cgctgaccag acggaactcg tagtgttcaa ggtagcgtaa gccgccgtgg
    59761 ataagtttcg aactggcgga agaggttgcg caggccaaat cctgcgcttc cagcatgagt
    59821 acggacaaac cgcgtccggc ggcatcagcc gcgatgcctg caccgttaat gcccccgcct
    59881 atcacgatca gatctttggt ttccatgctg ccctcttgca ctttcgttaa agttcaaaaa
    59941 tgttcgttat cgaacataat agcaaagaaa cgcgctattg gtaacatcga aaaaacattt
    60001 tagagtgata tgtataacat tatggcgtta agctactccg tcaacgtaca ctgggcgata
    60061 aaatgcctta attggcttca ccggcaataa tgaaagagcg attcatggaa caatttgaat
    60121 gtatcactgt agaagaggcg tatcagaaac tgcaccaggg cgcggcggtg ctggtcgata
    60181 ttcgcgatcc gcaaagttat gccatgggtc atgcgccgca ggcgtttcac ttgactaacg
    60241 atacgctggg cgcgtttatg cgtgagcatg gtttcgatac cgccgtgatg gtaatgtgct
    60301 atcacggcaa cagtagtaaa ggcgccgcgc agtatctgct ccagcaaggc tatgatgcgg
    60361 tttacagcat tgacggcggg tttgaggcct ggcatcgccg tttccctgcc gatgtcgcga
    60421 atggcgcgta atcccataaa gatgcagcct ccgacgagaa gggtatatat actgtcttct
    60481 tttgtatgga ctaagcgaca gcaataatgt tgatgattac ttcctttgcg aatcctcgcg
    60541 tggcgcaggc atttgttgat tacatggcca cccagggcgt cattcttact attcagcaac
    60601 ataatcaaag cgatatctgg ctggcggatg aatcgcaggc cgaacgtgtg cgggtcgagc
    60661 tggcgcggtt tatagaaaat cccggcgatc cgcgttatct ggcggctagc tggcagtccg
    60721 ggcagactaa cagcgggcta cgctaccgcc gttttccctt tctcgccacg ctgcgtgaac
    60781 gagccggccc tgttacctgg atcgtgatgc tcgcctgcgt ggtggtctat atcgcgatga
    60841 gtctcatcgg cgatcagacg gtgatggtgt ggctggcgtg gccgttcgat ccggttttaa
    60901 aatttgaagt ctggcgctac ttcacccata tctttatgca cttctcactg atgcatattc
    60961 tttttaacct gctgtggtgg tggtatctcg gcggggcggt agagaagcgc ctgggcagcg
    61021 gtaaattaat cgtcattacg gtgataagcg cgctgctaag cggctatgta cagcagaaat
    61081 ttagcggccc gtggtttggc gggctgtccg gcgtcgtcta tgcgctgatg gggtacgtgt
    61141 ggctgcgcgg agagcgcgat ccgcaaagcg gaatttacct ccagcgcggc ttaattattt
    61201 ttgcattatt gtggatagtt gctggttggt ttgactggtt tggcatgtct atggcgaacg
    61261 gcgcgcacat cgccgggctt atcgtcggtt tagcgatggc ctttgttgat acgctgaatg
    61321 cgcgaaaacg aacgtgaggc gtatccggcc tgtggtcgag atatttttcc aggccgggta
    61381 gggcgatgcc gctatccggc gcaaggttgg ttactttcag agattattca tgaaacaaac
    61441 acaacggcat gacgcgatca ttgaactggt gaaaaaacag gggtacgtca gtacggaaga
    61501 gctggtggag catttttctg tcagcccgca aaccattcgt cgggatctta acgatctggc
    61561 ggaacagaat atgattttgc gccaccacgg cggcgcggcg ttgccctcca gctcggtgaa
    61621 cacgccgtgg cacgatcgta aggcgacgca aacggaagaa aaagagcgca tcgctcgcaa
    61681 agtcgcggcc cagatcccca atggttcaac gctgtttatt gatatcggca cgacgccgga
    61741 agccgtagcg cacaccctgt tagggcacag taatttgcgg atcgtgacca acaatttgaa
    61801 cgtagcgaac acgctaatgg cgaaagagga ttttcgtatt atcctcgccg gcggcgaact
    61861 ccgtagccgc gacggcggca ttattggcga agcgacgcag gactttatcg cccagttccg
    61921 tctcgatttc ggcattctcg gtattagcgg tattgatagc gacggctcat tgctggaatt
    61981 tgactaccat gaggtacgca ccaagcgcgc gattatcgaa aattcgcgcc acgtgatgct
    62041 ggtggtggat cactctaaat ttggccgtaa cgcgatggta aacatgggca gcattagtat
    62101 ggtcgatgcg gtctacaccg ataccctacc accgccgggc gtgatgcagg tgattgccga
    62161 ccaccatatt caattagagc tgtgctaaaa agactgtctt atcaggccta cactctgcgc
    62221 gcgatggtag gcctgataag cgaagcgcca tcaggcacac gttaaacccc ataccccatc
    62281 atcttcagca actgctgcgc gtgctgtacc gcgtcctgac ggtgcgcgac gccgagtttc
    62341 tggtagaggt tgcggatatg cgtcttaatg gtggtcgcgg ccaccgccag ttcgccggca
    62401 atctgttcgt tgctgtaacc ggaatagata agtcctaaca cctgccattc acgctgggtg
    62461 agcgggctgg tgcgaataag ctccgggaca tccggatggt taagcagacg ctcgacgaag
    62521 ccttcgtcaa aatgggcgaa tttatgccgg tgatgttggt taatatatcg caggatgcgc
    62581 tgcgcgcgat gctgctccat ctccggcagc gtattgagct ggataagctg acgcaattgt
    62641 tgcgccatgg cttctccttc aatcacaaaa tggctgataa atccggtgcg gttggcgagc
    62701 tgtaaggcat caagcaatac gcgctgggcg tcgtttttcc gcccggattg ccagtaaagc
    62761 tgattgagta acagcagatt gcggtttaaa tcgctcatta agcgcaggct acgggcattc
    62821 tcatttaact cttccagcac gatttccgca ggctcgaatt cgcccagcag gatctgcgcg
    62881 cgggcgatat tgcgccactg gccttgcaga aaatggttat tggcaaacgc cggttttggc
    62941 gtatggcgta accagttggc ggcggatttc ttgtcgccgg ttaactgcca gtaaatgaca
    63001 cgcaccttat cggcgttaga gatccagtcg cagtgataac gaccattgcc taataatttt
    63061 tccagtcggt taagctgact acgggcatta tccagatcgc cgcgcgccag cgagcactgc
    63121 accagtaacg tcaggcactg caactgttgt tgcggctgga aggtggacag cacagcgata
    63181 ccgctgcgcg ccgaggcttc cgcttcgtca aggcgcgccc acgcccacag caattgcgcg
    63241 cggatacgta ccagaaactc atgcatcggc agttgttcca gatgttgctc tttgatcaac
    63301 tggaaggctc tctcctgcgt ttcccatgcg gcctgcagga atccctgggc gaactgaatt
    63361 tcgctttgtt gaattaagct ccacagcgcg taatgccaga cgtcatgatg gcgcgccatt
    63421 tgttcggttt gctgcatcag cgataaagac tggctgagat tgcctttaca gtgcagcact
    63481 tcgccgtgaa cggaggtcgc gacaatgcgg ctataaaacc aggcgagagg aagctcatcc
    63541 agcgccagtt tcgccagccg ctctgcctct tccggattgc cgtcgttgat ggcgacctgg
    63601 gcgcgcagcg cgttaaattc agcatgcagc gtgccgtcca tgaccccttt gatctcttgc
    63661 tcggcgcgcg ccagcagcgt attcacttcg ctgtagcggt gttggctttg catcagccag
    63721 gcctgtaaca acaccagccg cggattttcc agcaggcttt cccacggcag cgcttttaat
    63781 gactcttcca gcagcgccag ttcactgtga ttaaacagcc cccacgcatg gttaagcagg
    63841 atatcgcgca gcatttgcgc gtcacccgcc gccagcgcat gatgtatagc ttcgctggga
    63901 aaaccctgtt ccatccagct ttccgcggcc gcacggtgga tctccggcag ttccgccgcc
    63961 agttcccact ggcaacgctg gcgcagaaag ctaccaaaca acgggtgata gctaaaccat
    64021 tcgcccgtgt cgtccatgcg ttgcaggaat aacccctggc gctcaatctc ctccagccgc
    64081 atctggccgt tttcttcgcc ggtcacgcgc acgatcaacg cgtcattcat tgagcgtaag
    64141 atcgcgcttt taagtaagaa atgtcgggtg ctgacatcca cgttatccag tacttcgtcc
    64201 accagataat cagaaaggtg gctggcatta atcccggcaa gacggcgggc ggagtgatgc
    64261 gcagaggtat ggttctggcg cgcggagagg gcgatcaact gtagcgcagt ggcccaaccg
    64321 gccacatcat cgcacatgcg gctgctctca gcggcttcaa tgggcgacga aagacgacgg
    64381 tcaaaaaatt gctttgcttc ctgatggtta aaagccaact gctggctgcc gatttccaac
    64441 agctgatcgc gcacgcgcag gttagcgatg cccagttgcg gcaaattacg cgataacacc
    64501 accagggtga aattttccgg ctgatgccgt aagaaaaagc gcatcgcgtc gtgaatcacc
    64561 ggattggtaa tcaaatggta gtcgtcaatc accagataaa gcgggcgatg ccactgcgcc
    64621 agttcaataa agagctgtgc gaagagagac gtcaggctgg cgtactgacg tttttgcgcc
    64681 atcgcttcgc tggtagagca gtgtccgccg gtggcctgtt ggatagcggc gattaagtaa
    64741 ctggcgaatc gctcttgctg gttatcgcct tcgtcgagag agtaccagcc taattcattt
    64801 ttgcccgccg cccactgtga gacaagcgtg gttttcccat agccagcagg actggttacc
    64861 aggaggagcc tgaaattgtt cgcgccggaa agtttagcca acagccgctc acgaaccacg
    64921 gtatggtcga gacgaaccgg acgacttaat ttagacggaa tcaacatagc aatcacttca
    64981 ctgtgggaaa tgggggaact gcgatttttt tttgcgcttc gtaattaata gatataaggt
    65041 cggccagaaa gcattttaat gcaagctaag cagacttttt atgtgtctga atttgcactc
    65101 tgtcacaatt ctaaataacg gtattaaaaa agtattcggc gcggttgaaa cgagcgtcag
    65161 agctgggctg aggtcatatt tccgttattg taaataatgt cctggacagg atgcggattt
    65221 aacacaatgg cgataccagg cgtttaatta attatgttaa gttagtgaac ctcccgccgc
    65281 tgaatatttc aggtaataaa ctattttggc gttcatataa tcttcgaaaa tatccctccg
    65341 cggtttactg ttatttctgt ttattcattt gattatgcgt aacactgggt gtcgttgaca
    65401 ggaatcggcg cgtttataca ggggtaagtg gcggcgatca cacttttatg ctcatccccg
    65461 ctcctcctcc ctccctaatc agtgccggga ggaggaaggt caacatcgag cctggcaaac
    65521 tagcgataac gttgttttat tacccgagga cggatttcct atgtcacagc caaccttcaa
    65581 taaagatcaa ttccaggccg ccctgacgcg tcagtggcag cgtttcggtt tactgtcggc
    65641 gtccgacatg acgcctcgtc agtggtggca ggccgttagc ggcgcgctgg cggaattact
    65701 gagcgcgcaa ccggtagcgc agccgacgaa aggccagcgt catgtgaact acatttcgat
    65761 ggaatttttg attggccgcc tgacgggaaa taacctgtta aatctggggt ggtaccagga
    65821 cgttagcgat gtgctgaaag cgcacgatat taatctgacc gatctgctgg aagaggaagt
    65881 cgatccggcg ctcggcaacg gtggtctggg acgtctggcc gcctgcttcc tcgattcgat
    65941 ggccaccgtc gggcagtccg ctacgggcta tggtctgaac taccagtatg ggctgttccg
    66001 tcagtcattt gttgaaggca agcagatgga agcgccggat gactggcatc gcggcagcta
    66061 tccgtggttc cgccacaacg aggcgctgga cgtccaggtt ggaatcggcg gtaaagtcac
    66121 caaagaaggg cgctggaaac caggttttgt gattacaggc cagtcctggg atctgccggt
    66181 gttaggctat cgtaacggcg tcgcgcaacc gctgcgtttg tggcaggcga cccacgcgca
    66241 tccgtttgat ctgaccaaat tcaacgacgg cgctttcctg cgggcggaac agcagggtat
    66301 cgatgcggaa aaactgacga aggtgcttta tcccaacgat aaccacacgg cgggcaaaaa
    66361 actgcgcctg atgcagcaat acttccagtg cgcctgctcg gtagcggata ttctgcgccg
    66421 ccatcatctg gccggacgca agctgcatga gctggcggat tatgaggtca ttcagctaaa
    66481 tgatacccac ccgactattg ccatccctga actgctgcgc gtattgctgg atgaacacca
    66541 gatgagctgg gatgacgcct gggctatcac cagcaaaacc ttcgcctaca ccaaccacac
    66601 cctgatgcca gaagcgctgg agtgctggga tgagaggtta atcaaagcgc tgttgccgcg
    66661 tcatatgcag attatcaagc agattaacga tcgctttaag gcgctggtcg ataacacctg
    66721 gcctggcgat aagcaggtat gggcaaaact ggcggtggtg catgaccgtc aggtgcgcat
    66781 ggccaatatg tgcgtggtca gcggctttgc ggtcaacggt gtggcggcgc tgcactccga
    66841 tctggtggtg aaagatctgt tcccggaata tcaccagctt tggccgaaca aattccacaa
    66901 tgtcaccaac ggcattacac cgcgtcgctg gattaaacag tgcaatccgc agcttgcggc
    66961 gttgctggat aaaacgctga aaaaagagtg ggctaacgat ctcgaccagt tgatcaacct
    67021 cgaaaaatac gctgacgacg ccacattccg tcaacaatat cgcgacatca aacgggcgaa
    67081 caaagaacgg ctggtgaaat tcatccaggc ccgtaccggg attgagattt cgagccatgc
    67141 gatttttgat attcagatca aacgcctgca cgagtacaag cgtcagcatc tgaatctgtt
    67201 gcatattctg gcgctgtaca aagagatccg cgaaaacccg caggctgacc gcgtaccgcg
    67261 cgtattcctg tttggcgcga aggcggcgcc gggctattac ctggcgaaga acatcatttt
    67321 tgctatcaat aaggttgcgg aagccattaa taacgacccg gcggtgggtg acaagctgaa
    67381 ggtggttttc ctgccggatt actgcgtctc ggcggcggaa atgctcattc cggcggcgga
    67441 tatttccgag caaatttcta ctgccgggaa agaggcgtcc ggcaccggca acatgaaact
    67501 ggcgctgaac ggggcgttga cagtgggaac gctggacggc gctaacgttg aaatcgctga
    67561 aaaggtgggt gaagagaata tctttatctt tggccatact gtggaagagg tcaaggcgct
    67621 caaagccaaa ggctacgatc cggtgaaatg gcgtaaaaaa gacaaagtgc tggatgcggt
    67681 actaaaagag ctggaaagcg gtcaatacag cgatggcgat aaacatgcct ttgaccagat
    67741 gctgcatagc ctcggcaaac aggggggcga tccgtacctg gtcatggcgg acttcgccgc
    67801 ttatgtcgag gcgcaaaagc aggtggatgc gctgtatcgc gaccaggaag cgtggacgcg
    67861 cgccgcgatc ctcaataccg cgcgctgcgg tatgttcagt tccgatcgct ctattcgcga
    67921 ttatcaggcc cgtatctggc aggcaaaacg ctaagggagc gcgatggaaa ataaacgtct
    67981 cgatagtgcc gcgctggcgg cggggatcag ccccagttac atcaatgctc atggcaaacc
    68041 gcagtctatt ggcgctgaaa ccaagagacg tttgctggcg gcgatgcacg gcacgacaac
    68101 aggaccacag gcggtcgtgc cgaatgtgaa ggtttatacc gcgggtaaaa aaatggcgtt
    68161 gccggtagag gggcgcggtg agtttgcctg gctgctgact acggaagagg gcgagcatta
    68221 caaagggcgc gtgacgggcg gtaaaaaact taacctgccg gctacgttgc cggagggcta
    68281 ccacaccctg acgttgaccc aggatgaaca gcgtacgcac tgccgtatta tcgttgcccc
    68341 gccgcgatgc tatgagccgc aggcgctgct ggaggggaaa aaactgtggg gggcctgcgt
    68401 ccagctttat actctgcgtt cagaaaaaaa ctggggtatt ggcgatttcg gcgatttgaa
    68461 gtcgatgctg gtcgacgtgg cgacacgcgg cggcgcgttt atcggcctga acccgatcca
    68521 cgcgctttat ccggcgaatc cggagagcgc cagtccctac agcccctcgt ctcgtcgctg
    68581 gctgaacgtg atatatatcg acgtcaacgc cgtcgaagat ttccgcctga gcgaagaggc
    68641 gcaggcatgg tggcaaatgc ccgccacaca gcaaaagctg cgacaggcgc gcgatgcgca
    68701 atgggtggat tacgctaccg ttaccgcgct gaaaatcacg gcgctgcgga tggcgtggac
    68761 gcggtttgcc gctcgcgacg atgcgcaaat ggcggagttt cgtcacttta tcgcccgcga
    68821 aggcgaaagc ctttactggc aggcggcatt cgacgcgctg catgcgtatc aggtgaaaga
    68881 ggatgggcag cgctggggct ggccagcctg gccggaggcg taccagtcgg tagagtctcc
    68941 cgctgtaaaa caattctgtg aagcgcaccg cgaagaggtg gagttttatc tctggcttca
    69001 gtggctggcc tggcgccaat tcgccgcctg ctgggatacc tgccagagtt ttaaactacc
    69061 gattggtctg taccgcgatc tggcggttgg cgtagcggaa ggcggcgcgg aaacctggtg
    69121 cgaccgggag ctgtactgcc tgaaagcatc tgtcggcgcg ccgccggata tcctcggccc
    69181 gctcggtcag aactgggggc tgccgccgat ggacccgcat atcattgtcg cccgggcgta
    69241 tgagcccttt atcgacctgc tgcgcgccaa tatgcaaaac tgcggcgcgt tgcgcattga
    69301 ccatgtcatg tcgttgctgc gcctgtggtg gataccgtat gacgaaacag cggatcaggg
    69361 ggcttacgtc cattatccgg tagatgattt gctttctatt ctggcgctgg agagccaacg
    69421 tcaccgctgt atggtgatag gcgaagatct ggggacggtg ccagttgaga ttgtcggcaa
    69481 gctgcgcgat agcggggtct attcttataa agtgctgtgg tttgaaaatg accttgagaa
    69541 aaacttccgc gcgccaggcg catatccgca acaatcgatg gctgtcgcct cgacgcacga
    69601 tctccccacg ctgcgcggct attgggaatg cggtgacctg acgttgggta aagctctggg
    69661 gctttatccg gatgaagtga ttctgcgcgg gctgtatgag gatcgcgagc gggcgaaaca
    69721 ggggctattg gacgcgctgc ataaatatgg ctgtctgcca aaacgcgccg ggcataaggc
    69781 attgttaatg tcgatgacgc caacgctaaa tcgcggactt cagcgctata tcgccgacag
    69841 taacagcggt ctgttggggc ttcagccgga ggactggctg gatatggccg atccggttaa
    69901 cgtaccgggc accagcgatc agtataaaaa ctggcggcgg aaattgtctg catctcttga
    69961 ggctatgttt gccgatgagg gcgtaaacaa gctgattaag gatttggata agcgccgaaa
    70021 agcggccgcg aagaagaaga agtaataaag ccggggattt ccccggcttt atgatggtga
    70081 gagcacgtag gcctgataag cgcagcgcca tcaggcaatt ctggcgcaca ttgctgcctt
    70141 atccggcctg caaaccgcct cgcttaaacc accataccca gtagcagaca gccgatcagg
    70201 ccgcagacgg agatgatcgt ttccagcatc gaccaggatt taatggtctc gccgatagtc
    70261 aaattgaaat actctttgaa cagccagaag cctgggtcgt tgacgtgaga gaaaatcacg
    70321 ctcccggaac cgactgcgat aaccatcagt tcaggactaa cgccggtcgt ggcgatcagt
    70381 ggcgccgcaa tgccgcctgc ggtaatcgcc gcgacagtcg cagagcccag cgcgatacgc
    70441 agcaccgccg cgatagacca cgccatcaac agcggagaga cattggtttc atgcatcatt
    70501 gaagcgatgt atttatccac gccgctatcg accagcacct gcttgaacgc gccgccgccg
    70561 ccgatgatca gcagcatcat ggcgataatt ttgatggaag agaccagcgt atcgttaatc
    70621 tgatccattg aacgcccgcg gttcaggcca aaggtgaaca ttgcaatcag tacggcaatc
    70681 aacgtagcca ttaccgggtc gcccaggaac tcggcaacgg gcaggaaagc gtggcctttt
    70741 ggcagaatca tctcggcaac cgcacgcatc gccatcagaa tcaccggaac cagcgacgtc
    70801 cagacgctga cgccaaagcc cggcatctct tcttccgtaa aggttttcgc gctgtacagg
    70861 ccttccggga tcggcttatc gatgcctttc agaaaacggg cgtaaaccgg tccggcaagg
    70921 atcacggtcg ggatcgccag aatcgtacca aacagcagcg ttttacccat atcggcatgg
    70981 aaaatcgtgg cgatcgcggt tggacccggg tgcggcggca ggaagccgtg tgtgacggag
    71041 agcgccgcgg ccatcggcac gccgacgtac agtaacggga tattcgccgc tgcggcaatg
    71101 gtgaatacca gcggcagcat cagaacgaag cccacttcat agaacagagc gaagccgacg
    71161 gtaaagccgg ttaacactac ggcccactga atatgctttt taccaaattt cgcgatcagg
    71221 gtagtggcga tacgttgagc gccgccgcag tcggcaagca ttttgcccag catggcgccg
    71281 aaccccataa tcagggccag actgccaagc gtaccgccga caccggcttt gatggagccg
    71341 atgactttat ccagcggcat tccctgcatc aacccgacag cgagcgctac caggacaagg
    71401 gcgataaatc cgttcatttt gaagcggatc atcagaagaa gtaacaagat aacaccgata
    71461 gcaacgatga ctaatggcat gatttacctg gcctttactt tgttatgggt aacgtcattg
    71521 tttcgacgac aaattcctgt tgttcccgac gggaacagag tcgcaatagc accaatactg
    71581 attaccgttg aaacgaatga gcgtagtcag atgttatatg gatgttaggt gcccataaga
    71641 atgatacggg taacatatgg gtgttgaaaa tgaccctggc aggcaaaatt taaattatga
    71701 gacacaggtc atgttatcgg cgaaagaaga agaaccattg ttctgagatg tggctgatgg
    71761 cgcagaatgg cggcgtagac gccttattcg gcctacggtg gggcagacaa ggcccgacag
    71821 gcgcaagcgc catcgggcat ggatgcgggg aaaatcttag tagtatgagt gctcgccgcg
    71881 ctggtgttcg gtcagatcgc gaaccccttt cagttccggg aattcattca gcaactgttt
    71941 ctcgatccct tctttcagcg tgacgtcaac catcgagcaa ccgttacaac cgccgccaaa
    72001 ctgcagaatt gcatagcctt catcggtaat ttccatcagc gagacgcgac cgccgtggcc
    72061 cgccaactgc gggttaatct gcgattgcag agcatattcc acgcgctcca tcagcggcgc
    72121 gtcatcggcc actttgcgca tcttcgcgtt tggcgctttc aatgtgagtt gagaacctag
    72181 ctggtcggtc acgaaatcaa tttccgcgtc ttccagatag ggcgcgctca gctcgtcgac
    72241 ataagcggtc aacaggtcaa atttcagtgc agtatcggtg gcttctacgg cgtcgggcgg
    72301 acaataagaa acgccgcact ctgcgttagg agtgccggga ttaatgacaa atacgcggat
    72361 ttgcgtccct tcttcctgat ttgccagcag tttggcaaag tgcgcttgtg cagcatcgga
    72421 aatacggatc atagtaatgg cctaatagtt gactatttta gttggttata atacgcccgt
    72481 catcgaggct ctacaaggtt cgacacaggc accatacctg gacagtcgct gcgccgttgc
    72541 gcaaaagcag ttgcgcgatt tccgcgacgg tacttccggt agtgacgaca tcatccacaa
    72601 taaccatatg gagaccctgt accggcaatt caaggcgaaa cgcgtttttc aaattgcgct
    72661 tacgtaacct ggcgctgaga tgatgttgtg ttgcggtcgc ccgtacccgc gtgatggtct
    72721 ggctgtccca cgcgcagccc agccagtgcg ctaacggttg gcataacaga tcgctttggt
    72781 taaatccccg ccgccagtgt cggcgcgacc agagcggaac gctgacgatt ctgtcgggaa
    72841 gcggcaagcc agtgctgcgg cgcgccataa gtacttcctg caacagtaga cgcgccagag
    72901 cggcggcaat ttcgctgcgg cgggtaaatt taagctgatg caccagtaaa ctcaagggcg
    72961 gcgtatagtc actgacgctc accagacgct gccagggcgg cggtttttgc aggcagcgat
    73021 cgcaggggag cgaaggatgc ccggcaggta atccgcattg cggacacagg ctgacgcgct
    73081 gacgaacggc gcgcgcgcat acggagcaaa tcccccagtg gcttaacgcc agcggcattc
    73141 ggcatagcca gcataatccc ggtactgtta gcataggtgc atccttgtta gacaaaagag
    73201 aacagtaact gatgaatgac atctggtggc agacctacgg cgagggaaat tgtcatcttg
    73261 tgctgctgca cggatgggga ttgaacgcgg aggtgtggca ttgcattcgc gaggaactcg
    73321 gctcgcattt tacgctgcat ctggtcgact tgccgggcta tggccgtagt tcggggtttg
    73381 gtgccatgac gcttgaagag atgacggcgc aggtagcgaa aaacgcgccg gaccaggcta
    73441 tctggcttgg ctggagtctg ggcggcctgg tggcgagtca gatggcgctc acccaccctg
    73501 aacgcgttca ggcgctggtg acagtcgcct cttcgccatg ctttagcgcg cgtgaggggt
    73561 ggccgggaat aaaaccagaa atcctcggcg gattccagca gcagcttagc gacgattttc
    73621 agcgcacggt ggagcgtttt ctggcgctgc aaacgttagg gacggagacg gcgcgtcagg
    73681 atgcccgcac cttaaaaagc gtagtgctgg cgcagcctat gccggatgta gaggtgctca
    73741 atggcggact ggaaatctta aaaacggtcg atctacgaga agcgcttaaa aatgtgaaca
    73801 tgccgttttt gcgtttgtat ggttatctgg acggtctggt gccgcgtaaa atcgcgcctt
    73861 tgctcgatac gttatggccg cacagtacat cacagataat ggcgaaggcg gcccatgcgc
    73921 cgtttatctc gcatccggcg gcgttttgcc aggcgctgat gacgctaaaa tcatcgctgt
    73981 aaccagggcg ttgccgggcc caggccattc tgccagatta atggctttca gacgccagat
    74041 cggcaggcgc cagcccggta accctaagca cagtatcgcg atcgaaacca tcgtttagca
    74101 tggagcgggc aatgcgcaat gcggcgagcc gttggccttc ctgtttgcct tgttgtagcc
    74161 ctttctgtaa cccgttacga tgtccttcct gacgtaatct ttctgcgata gtcatgatct
    74221 tctccttatg ctgtgggata cgcatagcca cctggcggat aaacgtattg aagcgcgcgg
    74281 cgtcgccagt gtgcatcatg taattaaaca gactttgaag ctgggtgtca ttagcgtatc
    74341 ccttaaccag cagggcgacc agctgttcga caagccccat cagatcacgc tggcggatgt
    74401 gtttttgtat gagttccagc agcgcgaccc gtcggtgccg cataatctcg tcgtccggca
    74461 cgaccgtaat atcgaccaga ggaaaggcgg tggcgtatag cttacgcgcc atcaccgggt
    74521 cggcaaattc atccagccag cataatgaga acggatacgg gcttcggttt ccgtggtaaa
    74581 acagcattgg taccactaat ggcaacgtct tatgcccggc ctccaggtgc cgttgcattg
    74641 cagccattgc gtaacgcatc agccgaaatg ccatatgcgc gtccggcgta ctctgatgtt
    74701 caataaccac gtaaatgtaa ccgtcacctt cacttgtttc cagcgaccaa aggatatcgg
    74761 aataatgggg gcgtaaatcc tcttcaataa agctaccgga ctccagccgt aacgtattca
    74821 gattacagat ttgacgtaat gtcgacggaa gatggatttc caaaaaatcc cgtgcagtat
    74881 cggggtggca taaaaactgt ttgaataccg cgtcatgcgg cgtggatgtt gttgaggtcg
    74941 ccatatcgat ccgtcaccgg tgaagctcaa tggcgtgaca ctacgcgcag accgggctga
    75001 ttgcagtaga ggattagtgc gcttgcgagg cgcgtgggga gataaatgcg cacggcggta
    75061 acgctttcat ctttgtggaa ggcatgacgc aaaattgccc ggcagcgtga cgcgtaccgg
    75121 gcaatataac gcgggataaa ggccggataa gacgcgttac gtcgctaccc ggcgaaggtc
    75181 aacgcaaggc ccaccattcg cgcaggcagg ctttaccttc cggacagctt ttacaactgc
    75241 ctgaaaggca accgtccggt tcttccggga tacgtaccgc tttacccatg atctccagtt
    75301 gattcagcat ggcgtcgatc atgggctgcg gagcgtgcag cgtatggctg atctgcgttg
    75361 cctccatacg cccccgcagc gccagtagat cgcgaacctg tatcaatgaa gccatttttt
    75421 acatccctta gtgacaattg cccgcagtgc ccgaacaaca ggatgtgacg cttttgcggg
    75481 ttgccagcag ttcaatgtct acacggctgc gggcgcggcg tagcagactt aataccacaa
    75541 cgttaaagac gattaccgcc agaatacaga tcaggctgta agtcgggtgc tgactgaagc
    75601 tagtaacctg gtagaacagc gtggcgagcg aataggcgat attcagcccc cacaggatgg
    75661 agaagctcat ccagccgcgg ctggactcgc gggcgatagc gcccattacc gagatacacg
    75721 gtacgtaaag caggacgaaa atcaggtaac tgtacgccgc cgcggcgctg ccgaattttt
    75781 gatccatcac gcccatcgcg ccggtcgcca tttcgccgtc gcctttactc gcttcgatcg
    75841 ggttagccag tacgctcagg ctaaaggtgt ctttcaggct ttgccaggta tcgtcaaccg
    75901 cgcccagcag ttcatcgccg aggtgaaagt cggcaggatt aaacgcttcg tcctgaatat
    75961 tttcggcggt gtagagcgtg ttcagcgtac cgacgacaac ctctttcgcc atggcgcccg
    76021 taaacagacc cacggtagct tgccagttat cctcatggac gccgatcggt ttaaagactg
    76081 gcgtgatgac ccggcttaca gaggcgaggg cggagtcatt aatgttatcg acgattttgc
    76141 cgctcagcga gaaactgtta aacgcgctca ggaaaatact cacgatgata atgactttac
    76201 cggcgcgtag tacaaaacct ttcaggcgtt gccaggtctg gatgatcagg ctcttgatat
    76261 gcggtacgtg gtaaaccggc agctccatca caaacggaga ggcttcgcca cgcataatgg
    76321 tatgtttcag catcaggccg gttaataccg ccatgacaat acccagcacg tatagcgaga
    76381 agaccgccag cgcgccgttt tgcccgaaga aggcggcggc aaagacggcg aaaatcgcca
    76441 ggcgcgcgcc acaggacata aacggcgcca tcatgatggt catcaggcgt tcgcgcggag
    76501 cgtcaagcgt gcgggcgccc atcacggaag gtacgttaca gccgaagccg acaatcagcg
    76561 gcacgaagga tttacccggt agtcccagcg cctgcatcag gcgatccatg acgaaggccg
    76621 cgcgcgccat ataaccggag tcttcaagga aggagaggaa caggtacatc atcccgattt
    76681 gcggcaccag cggcaggacg gtattgatcc cgccgccaag accttgcgcc aggaagatgg
    76741 ttaaccaatc cgggaagtgc agcgtgtagc caatccattg aatgccatga ataaagatgg
    76801 cgacggaacc ggcatcaaac aggggttgca acgcgccgcc gatgttaatg gcgagcagga
    76861 acatcaggta catcacgaac aaaaaaatcg gtaagccgag gaagcggttc aggataattt
    76921 tatcgaccgc cctggtgaag cggctgggtt cggctgtcag ggtattgctg accacgtcgc
    76981 aaatagcggc gatacactgg taacgggcgt cggcgatatg cagcgccggg tcgtccattt
    77041 cgtccttcag acgggcaagg gaggtgtcca ggttttgcgc cgcctcgcct gcgtaagccc
    77101 ggctgtagat atcgccctcc agcatttgca gacccagcca gcggcgctgt tgtaaaggca
    77161 tctcctgggc catcgcgtcg gccaggaaac ccgcttcgcg cagcagcggc tgggcataat
    77221 gcaccagttc gacgttgtcg ttagcgttgt gacgatcaat ggccagtttc agcgcctcga
    77281 taccgcgacc gcgagtcgat accagcggta cgacagggca acccagacgc gtggacagag
    77341 cgtcgacatc aatacgaacc tgctgttttt cggcgatatc cagcatgttg agcgcgacaa
    77401 tacaggggat acccagctcc agcagctgca gcgtcaaata gaggttgcgc tccagattgg
    77461 aggcgtccac aacgtttatc aacaggtcgg cgtcgccgct caggatgtag tggcaggcga
    77521 tctgttcgtc gagagaggtt tgtgacgaga tggtcgtcag agaataggtg ccgggtaaat
    77581 ctaccagcgt gacctggtgg tcagttgtcg cgaactggcc ctctttacgc tcgacggtga
    77641 cgcccgccca gttccccacg cgctgacgcg cgccggtgag ttggttaaat aaggtggtct
    77701 tgccggaatt aggattacca attaaaccaa tggttaattt tttcattttt atagactcac
    77761 tgtattaaca ggaaaccgct tccacttcta ttaacgccaa atccttttta cgcaaaacca
    77821 gactcacgcg tcgtgtttcg atatggatcg gatcccctaa gggcgcgacg cggacaacat
    77881 taaatgaaga gccgggcaac atgccgagcg aaagcagttt ttgacgatac gccgggctga
    77941 tttcacgcgc aaagccggtg attttccacg cagtgtcagg agtgaattgc atacgaccta
    78001 cttgtttctt actaactgga tgtatacctc atgcggcgct caggggggcg gcaggagacc
    78061 cgatgtttag ccaacgaagg aaagagtaaa taatcaacaa cacaatgata atgagaatgg
    78121 tttctatctt caacgattaa aatgtgacgg aatgtacaaa taagcgataa tttgcgccga
    78181 tgttgatatg gctcaacatt tatttgtctt tttgcaaata cctctaatgt gcaaatattc
    78241 accgttttta atgtttaatt aaggtttcat ctgttaataa agtgataatt aatagtgcgg
    78301 atagcagaag gaaattaatt aacagattct aatgggtaag atttaattgt taattaaaaa
    78361 agaaagggtt ggacgtattg caaaatcgca ggccggataa gaagtaaccc ggcctgcgta
    78421 ttacccgatt agcgtttttt tcccattgcc gctgccagcg cgtccatcat ggcgctgtta
    78481 ccggctggct gggcgtcacg accgcgcggt ttcgccgctt ttgacgccgg gcggttgccc
    78541 tgagcgcgat cggcaccgcc gccgcggcga gcggcggttt cgccgggctg ttcgtccaga
    78601 cgcatcgtca gcgcaatacg cttacgttgc agatccactt ccagcacttt caccttcacg
    78661 atgtcgccag cttttaccac ggtgtgtgga tcgtcgacga acttagtcga cagggaagag
    78721 atgtggacca ggccatcctg atgaacgccg atatcgacaa acgcgccgaa gttagtgacg
    78781 ttagtgactg ccccttccag aatcatcccc ggcagcaggt cgttcatggt ttcgacgcca
    78841 tcggcgaatt gcgcggtttt aaattcagga cgcgggtcgc ggcccggttt ttccagctct
    78901 ttgatgatat cgctcacggt cggcacgccg aatttatcgt cggtaaaatc agcggccttg
    78961 aggtgacgca attcgttgct gttgcccatc agatctttta gcgcttgctg cgtcgccgcc
    79021 agaatgcgtt cgacaaccgg ataggcttcc gggtggacgg tggaggcatc cagcgggtta
    79081 tcgccgtggt taatacgcag gaagcccgcg cactgctcaa acgctttcgg ccccagacgg
    79141 ctcaccttca acagttgctg gcggttctgg aactgaccgt tctcatcgcg ccaggcgacg
    79201 atgttttgcg ccatcatgcg cgttaagcct gcgacgcggg tcagcagcgg tacggaggcg
    79261 gtattcaaat cgacgccgac ggcgtttacg cagtcttcga ccaccgcatc cagtttacgg
    79321 gccaattggg tctggctgac atcgtgttga tattggccga cgccgatcga tttcggatcg
    79381 attttcacca gttccgccag cggatcctgc agacgacgcg cgatagagac cgcgccgcgc
    79441 agggagacgt cgagatccgg aaactcctgc gccgccagct cagaagcgga atacacggac
    79501 gcccccgctt cgctgacgat cactttctgc gccgtcacgt tcgggaactg tttctgtacg
    79561 tcgagataga aacgttcggt ttcacgcgaa gccgtaccgt tgccaatcgc gaccagttcg
    79621 acgtggtatt tttcgcacag cgcggcgatc acggtagccg ctttggccgc ctgaccggta
    79681 tgcggataaa tggtatccgt cgccaccagc ttgccggtgc cgtcaacgac agcgactttt
    79741 acgccggtac gcaggccagg atcaaggccc atcgtggcgc gcaggcctgc gggggctgcc
    79801 atcagcaggt cgtgcaggtt acgcgcaaac acgttaatcg cttcgtcttc cgcacgttcg
    79861 cgcacggtgc ccatcagttc ggtttcgagg tgcattaaga ctttgatacg ccacgtccag
    79921 ctcactacgc ctttgcgcca gctatccgcc ggggcgttat ttagccgcag gccgagatgg
    79981 tccatgatga tttgctcgca gtagctctct ttcggcggct catcaaactg tgggtcggca
    80041 ttgagcgaaa gttgcagaat gccttcgtta cgaccacgga acatggccag cgcacggtga
    80101 gacgggacgt tagcaatggg ctcatgatgg tcgaaatagt cgcggaattt tgccccttct
    80161 tcctctttgc cgctcacgac tgtggcgacc agatgggcat tcttccacag gtaatcacgc
    80221 actttcgcca gcaatgcggc gtcttcggca aagcgctcca tcagaatgta gcgtgcgccg
    80281 tcgagcgcgg ctttcgtgtc cgccacgcct ttgtcgccat caatgtactt tgccgctttc
    80341 acgtcaggat cgtgggacgg ttcgttccag agcagatcgg ccagcggctc aaggccggct
    80401 tcaatggcga tttgtccacg ggtgcggcgt ttaggtttat agggcaggta gaggtcttcg
    80461 agctcggtct tacttaacgt agcgttgatg gcgccagcca gctcatcggt cagtttgcct
    80521 tgttcggaaa tggacttgag gatggcctga cgcctgtctt ccagctcacg cagatagccc
    80581 agacgcgttt ccaggttacg caactgcgtg tcatccagac cgccggtgat ttctttacga
    80641 taacgtgcga taaacggcac ggtgttccct tcgtcaagca ggcgaacggc agcttcaacc
    80701 tgcccggcat ttgcctggat ttcacccgca ataatgcggc agaaagaatc attcatcatg
    80761 ggttagcttc gtcttcagga taaaaatcag gggatagtta tacggattgg ctggcaaaaa
    80821 tgccagccat cagcgggggc ttaggattct tcttgtctta tttgacgtat tcgatcgcat
    80881 tgacgtacca gtttgcttcg ccgacagggg tgttgaccac cgccagatcg cccacttctt
    80941 ttttcagtag cgcccgcgcc atcggcgagt cgatagagat gtaatcctta cgtccgaaaa
    81001 tttcatcgta gccgacaatg cggaacttca gcgtatcgcc gtcatcattt tcgatttcca
    81061 cccaggcgcc gaagaagact ttgccctcct gctgcgggga ataatccacg attttgagat
    81121 tttccatgca tttggtcaga tatctgacgc gtctgtcgat ctcacgcagg cgctttttat
    81181 tatactgata gtcggcattc tcgctgcggt cgcccagact cgcagcccag gtcacttttt
    81241 tggtgacctc cgggcgctct tcacgccaga gataattgag ctcttgtttg agtgtttcgt
    81301 acccttcgcg ggtgatcagg ggcgttttca tctcgttgat ttacctttgc tgtcgatatt
    81361 gcgcacacgg ggtataacgt gatcgtcccg acagaataaa taatggggtt gccgattaat
    81421 tgtatattta agctgctgtt aaatatgctt tgtaacaatt tagcctgaaa ttcataccag
    81481 aatttgctgg tgactcacgt gagctttttt aagaatacac acttacattt gttgcgaacc
    81541 tttgggagta cagacaatgc aagagaatta taagattctg gtggttgatg acgatatgcg
    81601 tctgcgggcg ctactggaac gttatctgac cgagcagggc ttccaggttc gaagcgtcgc
    81661 taacgccgag cagatggatc gtctgctgac ccgtgaatct ttccatctca tggtactgga
    81721 tttaatgctg ccaggtgaag atggtctgtc gatttgtcgt cgcctgcgta gtcaaagtaa
    81781 tccaatgccg atcattatgg tcacggcgaa gggtgaagag gttgaccgta tcgtcgggct
    81841 ggaaatcggc gccgatgact acattcctaa accgtttaac ccgcgcgagc tgttggcgcg
    81901 tatccgcgcc gtgctacgtc gtcaggcaaa cgaactgccc ggcgcgccgt cgcaggaaga
    81961 ggccgttatc gcgttcggta agttcaaact gaacctcggt acgcgcgaga tgttccgtga
    82021 agatgaaccg atgccgctga ccagcgggga gtttgcggta ctgaaagcgt tagtcagcca
    82081 tccgcgcgag ccgctctctc gcgacaagct gatgaatctg gcccgtggcc gcgagtattc
    82141 cgcgatggaa cgctccatcg acgtccagat ctcccgcctg cgccgtatgg tggaagaaga
    82201 tccggcgcat ccgcgttata ttcagaccgt atggggcctg ggctacgtct tcgtaccgga
    82261 cggttctaaa gcatgaggcg aatgcgcttc tcgccgcgaa gttcatttgc ccgcacgctg
    82321 ttgctcatcg tcaccttgct gttcgtcagc ctggtgacga cctacctggt ggtgctgaac
    82381 ttcgcgattt tgccgagcct ccagcagttt aataaggttc tggcttacga agtccgtatg
    82441 ctgatgaccg ataagctgca actggaggac ggcacgcagt tagtcgtgcc gcctgcgttt
    82501 cgccgggaaa tctatcgcga gctggggatc tctctctaca ccaacgaagc cgctgaagag
    82561 gccgggctgc gttgggcgca acactacgaa ttcttaagcc accagatggc gcagcaatta
    82621 ggcggcccga cggaagtgcg ggttgaggtc aacaaaagct cgcccgtcgt gtggctcaaa
    82681 acctggctgt cgcccaatat ctgggtgcgc gtgccgctga ccgagattca tcagggcgat
    82741 ttttctccgc ttttccgtta cacgctggcg atcatgctcc tggcgatagg cggcgcgtgg
    82801 ctgtttattc gtatacagaa cagaccgtta gtggatcttg aacatgccgc cttgcaggta
    82861 gggaagggaa ttattccgcc gccgctgcgt gaatatggcg cctctgaggt gcgctctgtg
    82921 acccgggcgt ttaaccatat ggcagccggc gtgaaacaat tggccgatga ccgtacgcta
    82981 ttgatggcgg gcgtcagcca cgacttacgc acgccgctga cccgtattcg tctggcgacg
    83041 gagatgatgg gcgaggaaga cggttatctc gcggagtcga tcaataaaga catcgaagag
    83101 tgtaacgcca ttatcgaaca gtttattgac tatctgcgta ccggtcagga aatgccaatg
    83161 gagatggcgg atctcaattc cgtgctgggc gaggtgattg cggcggaaag cggctatgag
    83221 cgtgagatta acactgcgct tcaggcaggc agcatccagg tgaaaatgca cccgctctcg
    83281 attaagcgcg cggtggcgaa tatggtggtc aatgctgccc gctatggcaa ctgctggatt
    83341 aaggtcagca gcggcaccga gtcgcatcgc gcctggttcc aggtagaaga tgacgggccg
    83401 ggcattaagc cggagcagcg taaacatctg ttccagcctt ttgtgcgcgg cgacagcgcc
    83461 cgtagcacca gcggcacagg gctggggctg gcgattgtgc agcgcattat tgataaccat
    83521 aacgggatgc tggagattgg caccagcgag cgtggcggat tgtcgattcg cgcctggcta
    83581 ccggttcctg tggctcgcgt ccaggggacg acaaaagagg cataagaaag ggaggtatta
    83641 ccctcccttt cttcttaaca ctggatgacg ctgttcaaag ccgccatccg gcctgttcct
    83701 tacagcttcg gtccggcgct aaccagcgct tcgcctgccg gggtatccgt atacttctcg
    83761 aagttctcaa tgaacagttt cgccagcgcg gtggcttttt cctgccattg ttccggcgac
    83821 gcgtaggtgt tacgtgggtc gagaatgtgg gtatccacgc ctggcagttc agtcgggatc
    83881 gccagatcga acagcggcag gcggaaggtt tccgcgttat caagagaacc gttcagaata
    83941 gcgtcaataa tcgcgcgcgt atctttgatg gagatacgtt tgccggtgcc attccagccg
    84001 gtgttaacca gataagcctg tgcgcctgct gcctgcatac gtttcaccag cacctcagca
    84061 tactgcgtcg ggtgcagcgt caggaacgcg gcgccgaagc aggcggagaa ggtgggggtc
    84121 ggttcggtga cgccgcgttc ggtgccggcc agtttagcgg tgaaacccga caggaagtgg
    84181 tactgcgtct ggttagcggt taaacgggaa accggcggca acacgccgaa agcatccgcc
    84241 gtcaggaaga taaccttggt ggcgtgacct gctttggata cgggcttaac gatgttatcg
    84301 atatgataga tcgggtaaga gacgcgggtg ttttcggttt tggaaccatc gtcgaaatct
    84361 acggtgccgt cttcgcgcac ggtgacgttt tccagtagcg catcacggcg aatcgcatga
    84421 taaatttctg gctccgcttc tttcgacagt ttgatggttt tggcgtagca gccgccttca
    84481 aagttgaaca cgccgtcgtc atcccaaccg tgctcatcat cgccaatcag acgacgtttc
    84541 gggtcggtgg acagagtggt ttttccggta ccggaaaggc cgaagaagac cgcgacatcg
    84601 cctttttcac ccacgttggc ggaacagtgc attgaggcga tacctttgag cggcagcagg
    84661 tagttcatta ccgagaacat cccttttttc atttcgccgc cgtaccaggt gccgccaata
    84721 agctgaatac gttcagtcag gttgaacgcc acgaagtttt ccgagttcag cccttgctct
    84781 ttccactgcg ggttggtgca cttcgcgccg ttcatgacaa taaagtcagg tttgaagcct
    84841 accagctctt cgtccgttgg gcgaatgaac atatttttaa cgaagtgggc ctgccaggcg
    84901 acttccgtaa taaagcgcac ggaaagacgc gtatcggcat ttgcgccgca gaacgcatca
    84961 acaatgaata agcgtttacc ggaaagctga tgcgtcacca gacctttcag gtgttgccag
    85021 gtttcctggg aaagcggctt attatcgttt ttacctttac ccttatcgga ccaccacagc
    85081 gtatcacgcg tggtgtcgtc gcgaacaata tacttatcct taggcgaacg accggtaaaa
    85141 ataccggtat caacggcaac agcgcccagg ttagttaaca cgccacgctc atagccttcc
    85201 agaccaggat taagttcttc ctgataaagg gtgtcgtagc tgggattgta aacgatatcc
    85261 tggacgtcgt tgataccata agccttgaga tcttgcgggg ttaaattgtt aacgcgcata
    85321 tcactgctcc ttagccaata tatattaccg aaaatagtaa ggttttttga ggttggttaa
    85381 ccgcgacaag gctcatagat ttacgtatct ggacaaaatc acgattgacg aaaaacactg
    85441 tgactcctgt cacgcagcgg cggttattat ggcaggaaac ctacttttgt tgtggaaaat
    85501 gttctgaaaa cgttaaaagg aagtgttttt gaccgacata atgtgactgt aatcgcattc
    85561 atgtaagaaa gttacgtaac accaacatta acaatatcga ttcacctctc tgcgtttttt
    85621 tctgaattat gcatgacgac gcctggcggt gaacagatgg tgcaataatg cggctttctc
    85681 atcattctgg ataacgacat ggaaagtgta gcgctttcac gtactactcg ctggggtatg
    85741 ttgctcactg gtttgctgca gggcgtcttg tgctacctgc tgatggcctg gctggtacca
    85801 caaaatagcg actggctgtt ctatggtatg cctgcgacga tagcgttgtc gtcaatgcta
    85861 ttgcttaccg tggtctcttt taaacagcgc gcgctgtggg gctggctggg gctgatcttt
    85921 gtggtcgtgc tggcaatgag cggctggctg aaatggcagg ttgaggcggt ggagaaatgg
    85981 cgcctggccg agctcctctg gctgtatggt ctccggcttg tgttgatggc gatgctggta
    86041 ttaccctgga tgcaatatca gttacattcg caaaccggtt cggcgcgtta tccccagttt
    86101 tatctgcggt tatggcataa cgtactgaca ttgtttatcg tcctggtcgc caacggactg
    86161 ttctggctgg tgcttctgct ctggagcgcg ctattcaggc tggtgggcat ccgctttttc
    86221 agcacccttt tctttgaaac tgaagccttt atttatgtga ccatcggcct gattacggcg
    86281 ctggcggtca ttctcgcccg cacgcagtcg cgccttgtgg cggcggtgca aaagctgctg
    86341 acgctgatcg cgacgggttt actgccagtg gtgtcgctgc tggcattgct gtttattgtg
    86401 acgttaccct ttaccggact ggaggcgatt tctgcgcgtg tttccgctac ggggctgcta
    86461 tccacgctga cgctgatgct gctgctcctc gtggcgattg tcaacgaacc gcaaaagcgc
    86521 gtattaccct atccgcgcgt actacgcggc atgattagcg cctcgctgtg cgttgccccg
    86581 atatatatgc tgctggcggg ctgggcgtta tgggtacgca ttcagcaata cggctggacg
    86641 ccggatcgtc tgtatggcgc gctgacggcg tctgtcttgc tggtatggtc cttcggttat
    86701 ctgatcggtc tgttacgccg cggacgcgac cctgatgagt ggcaaggcaa ggtgatactg
    86761 agcgtctctt tgttgacgct ggtgatattg ctgttgctgg cctcgcctgt acttgatgtc
    86821 tggcgtatta gcgtcaacag ccatatggcg cgttaccata gcggtaaaat tactgcggat
    86881 cagatcagcc tgtatatgct ggatcacagc ggcaaacctg gccaggaagc gctgaaatcg
    86941 ttgcgggatg acgaggcgtt tacgcagaac agaaagcgca atcgtgaact gatgacgttt
    87001 ttgcagagaa ataaggtccc tccgacggcg gacgatttag cgcgggtggt gatgattgcg
    87061 cccggtagcc agaagccgga tgccgcattt tgggcgtttg tcaaagagca gagttattcg
    87121 gacgcttcct gccttgaacc ggatgcctgc gtgctggtga gtcaggatct taacggcgac
    87181 ggtcagcctg agcaggtgct gtataacttt attgttgccg agagccaggt ctacggctta
    87241 aaagagggga aatggacgca gaaagcgttc gcccgattgc cggacgggtt ttctaagacg
    87301 caactgttgc acgcgattgc cgggcatcgg ttagactcag cccccaaagc ctggcgcgat
    87361 atcattgttg atggtcagcg gttggatgtg gattactaca acgagtaagc tttttgccgg
    87421 atggcggcat aaatgcctta tccagcctac ggagcgggat gctgtaggcc agataagcgt
    87481 agcgccatca ggcaatgacg ctgccgacta cgaggcgatt aatgaacctg tggatcggca
    87541 ggagaggcgt tgttacggat ctccgcgata tccatcgcat tgaacaggta atgattgccg
    87601 cagtaatcgc agtgcatatc gatttcgcct tcttccgcca gaatgctgtc cacttcttca
    87661 tccggcaatg ttttcagcgc gcccgcgcaa cgttcgcgtg aacaggtgca tttgaattca
    87721 acctcttgcg gatcgtagag cgtgacttct tcttcgtgat acaaacgcca cagcacgtca
    87781 tttgccggta atgtcagcag ctcttcgctt ttaatggttt ccgtcaacat ggccagatgg
    87841 tcgaaatcct ccgcctgcgc gttctgtgcc ggcatcacct ggagcaacat tccacctgcc
    87901 gccggtttac cgtcgacatc gccggtacgg ataaacaggc gcgtcggcaa ctgctcggag
    87961 cgcaggaagt aatcttccag gcacgccgcc agagtatcgc cttccagacc caccacgccc
    88021 tgatagcgtt caccctcttc cggcgtaatg gtgatcacca gatagccgtt gccaaccagc
    88081 gttttgagat ccgcattgtc agggatatcg ccctgaacgc gagccacgcc gcgcatctgc
    88141 tgctgattat tgccattgat caccgccagg cttaacggcc cgtcgccctg gagctgtacc
    88201 gtaatgtcac cggcaaactt cagcgtcgcg gtcagcaggc tagtggcgac cagcagttcg
    88261 gccagtacgg ttttcaccga ctgcggatag ttatgattgt cgaggatctg ttgcaaggtt
    88321 tccgaaacgg tcaccagctc gccgcgaacg gcaaagtttt caaacagata acgatgtaat
    88381 tggtcatgtt gcggcataat catctctctt gcgggtgaca gttattcgct gtcgccgtgt
    88441 ttaaatcgta acaggtcgcg gcgctctttc ttgtccggtc gcctggccgg atgcggcatg
    88501 gtcagggcgt taagcttgcg cgcctgcgcc attttttcgc gtttttccac gctttccgcc
    88561 gtctcttcat acagagcgac ggcttcgctg gccggacggc gctgttcggt gatggcttta
    88621 acgatcaccg tccgttcgtc atttccctga cgcagggtaa gggttgcgtt cagctcgacg
    88681 attttgctcg gcttactgcg ctggccgttg taatgcacct taccgccttc aatcatctcg
    88741 cgggccagcg cgcgggtttt ataaaaacgc gcggcccaca gccatttatc cagtctgacc
    88801 tcaacggagg acttttcttt catggcgtct ccttcacttc agcgagggga tcagacggcg
    88861 gtagtcgttc agggacggat ggcgcgtata gtgcttttcc gccagaccgg aatcgggatt
    88921 cgtcacgcca agacagtagc gaataccaaa ccgggcggcg gcgtcgagaa tcggttcgct
    88981 gtcatcgata aacagcgttt tctctgcgct tattcccgtt tcctcagtga cagcgcgcca
    89041 taaccgctga tcctctttgg gataaccaaa tgtgtgggtg gaaagtaata aatcaaggtg
    89101 tgaggccaga ccggtatgct ccagcttcac cgccaggtta tgtggatgcg cattggtgag
    89161 cagaatccga cgttttccgc tggcttttaa cgcattcaga aacggtacgg tatcgtcgcg
    89221 caaaacggcg cgcggccctt gcgccgtcgt catggcgcaa atatccagac ccagacgctc
    89281 gctccagtaa tccagacagt accagtttag cgtatgctgt acggcatgat actgctggcg
    89341 aatatattcc tgcgcgtcct gcggcgaaat accctgctgc gcgccgtagg tttccggtac
    89401 cagcttttgc cagaaatagt tatcgaacgc gagatcgagc agcgtgccgt ccatatccag
    89461 caaaacggta tccacgtttt gccagtcaat atcaatatgc atggggaact ccagggtaac
    89521 gcaatttgcg cgacagggta gcataccctg tcgcacggcg gcgctatcag atgagatttt
    89581 ccggagagac ggttaacctg ggattgaggc agctttcata gtattcctgg atgtccgcca
    89641 tacgggtacg gtggcgttga taacgcctga acgcctgaat gccgttgtag accgcgctca
    89701 ctatcattgc cagcatcagc agcgtggtgc cgaggtaacg ccaccagccg gatttatcgg
    89761 ggatacgatg caggctgata tgctgcgtgc cgttggcatc ggtatacacg ctggtgacaa
    89821 tgccctcggc gctaaatggc gtctgcatga gcgtttgcgc cagacgctgg aaggcgctcc
    89881 actgttcctg cgcgggatag tcatacagcg gcgttgacgg ccaggcctga tcaaccagtt
    89941 cgctgccttc atcgctggcg atcaggaatc cgccgggagc ggggctattc agcgactggg
    90001 cggcacgcgc ggtctcgcga gaaataaacg gcgccgttga ggtcgtgacc agattttcca
    90061 gcgactctgc gcttacgggg cgtagcagca cgttgacgcc gtccagtttg ccggcgttcg
    90121 cgcgtttcac cagcgcgttc cagtccttac tgttaccgag attaaccagc gcatttttca
    90181 ggcgcacgca ctcgtcttcc gccgcgcaca aatcagcggt tttcagaaca atatcgccaa
    90241 agtcatctaa taataccatg cccgattttt ggatcgcgga gcgtaaagat gcgcttacgc
    90301 gcgagtcgtc ttcgggtttt ggatggagct gacgatttac cgcctggctt agcgccatcg
    90361 ctttattcac cagatctgat tccggcagcg gtagcgcagg cgcgtcattc cagatgattt
    90421 gcgagcaatc gaacggcata aacggtgagt tagactgccc gctccaggtc gccccggaat
    90481 gaatattaca cattccttta ccgctcaggt gcagcgtatc gcccacccgt acgccagcct
    90541 tttcaagctg ttttaccgtt gtcgcttcaa tggtttgcgc gcctttcatc cacgatagcg
    90601 tgaacttgat tggcatatcc aacgggatcc agaacagcag cataaacaac accagcagcg
    90661 aaccgatagc aataacagtg ctgcgtaacc agtgctgcaa cgggaagttt ttcacttcat
    90721 catgcaggga taaaaaacgg ccctggcggg cgacatggcg atcaaggtaa atatcaatat
    90781 ccgtttgttg cccaagatcc tgcgtaatgt aaggttgcca gtgggcaggg taaataaggt
    90841 cgatgatgcc cagggaaata ttgttaatct gctcctgatt attctcccca aacagtcccc
    90901 agcggcgggg cgttccccgc agacagtgaa tttcccgcag cgcgcttttc gacggcggcg
    90961 caaaaagccc ccaaagtccg gctgccagca gcaggatcgc gccgcctatc atccacggta
    91021 caaaaacgtc tggcgttatc agacagaaaa agaataacaa aaaggaggcg acgattaaca
    91081 atgcttcgcg caagccagcc gggcggctga gcgcatattc ttcgtgggtc tcctgacgga
    91141 tgttcaacag ctcaatctgc tcgctctctt cgccgcgaat cgacgcctgc gtagaggccg
    91201 tattctgtag cgcgtagccg cgcgactcct gcatatactc ttgcagcgta tggccgttta
    91261 aagagatcac cagcggcagc gtatccgtga ggattagctc aacgttgttt tcatcattga
    91321 tgtactgttc ccagaaaggc ggcagatgga cttcgacgga gtcgaggtag tagcgccatt
    91381 tattaggatc gtcagtggta atgccgtagc gggtgatgga gtgggtcagt atcacgacac
    91441 tgttgctttc cgcgttcagc gtcagcgaga tgggcgcagc actggcgcct gtcggccccg
    91501 gaacttgctg gatctggcta aggttatcga gatagttttc taccgcgctg cgctcttcgg
    91561 gcaacagttt acgcgtttgc gcgtcctgaa aggcgctgaa ccacggtaag ctccctcgtc
    91621 tggactttac ccggaaccgc catattgcca gtagagagca ggccagcaaa gcagctataa
    91681 aaatcagaat ggtgctcatg ctttccccat cttactaagt ctgtcaggcg tggtcagtcg
    91741 caccctgtcc aataaacatt tttctgtggt tggctatcgg caagcgtgga gttgaacttg
    91801 agcattgtaa agcgcatccc agtgaaggca aatcatagca ataccaccaa aaacggaata
    91861 tcagcaaatt cctggagtta tttcaaccta ttgactttta atttgaaata agaattaatt
    91921 tttattacgt tacataaatg taaataaacg gcaattcgca ttgccgaaac cgtgcggtat
    91981 gtcgcacaat gaccacagat tacactgcaa agattctcac aatgagcaaa tcattacaaa
    92041 aacccaccat tctgaaagtg gaaaccgtcg cacaatcccg actgtttaac gtagaaagcg
    92101 tggatctgga gttcagcaac ggcgtgcgtc gcgtgtatga acgtatgcga ccatcaaccc
    92161 gtgaggcggt aatgattgtg ccgatcgttg atgagcatct gattcttatt cgtgagtatg
    92221 cggtgggaac cgaatcctat gagctgggct tctcgaaagg attgatcgac ccgggcgaga
    92281 ccgtttttga agcggcgaac cgggagctca aagaagaggt cgggtttggc gcgcataacc
    92341 tgaccttctt aaaaaaactc agcatggcgc cctcttattt ttccagcaaa atgaatatcg
    92401 tggtggcgga agatctctat ccggagtcgc tggaaggcga cgagcctgag ccattgccgc
    92461 aggtacgctg gccgctggcg catttaatgg atctgctgga agaccccgat tttaacgagg
    92521 cccgcaacgt cagcgcgctg tttctggtac gcgagtggtt gaaagcgcag ggccgaattg
    92581 cctgatggcg cggcgttgat caagccaacg gaaagtttgt ctccccgttc gccgtcatcc
    92641 gctaaacaca ataaaaaagg cgccggagcg ccttttttga tcagaacagt tcgtgtgttt
    92701 caccattatc aataatggtg gttcccacct cgtgtaccgc ctgttgtgtc ggctgcgtgc
    92761 cttcgatgaa atactcttca cggctgttac cgccgctcgc cagttgtccg gtactgcggt
    92821 cgatattcac cgtgacgatg cccggcggcg gcgttagcgg ctgttccggc acgccttcca
    92881 gcacggcttt catataggcg tcccatgcag gttgcgcgct cttcgcgccg ccctcatagc
    92941 cggagatttg atctttgatc gcgccggaag cggtggtgcg gcctaaatca cggcggtgat
    93001 cgtcaaagcc gatccatacg gaagtgacga cgccaggacc atagccggag aaccatgcgt
    93061 ctttcgagct gttggtcgta ccggttttgc cgccgatatc gcgacgttta aggtcgcgcg
    93121 ccgcacgcca gccggtaccc atccagccgg gttcgccgaa gatattggtg ttcagcgcgc
    93181 ttttgatcag aaacgccagc ggcgtattga tcacatgcgg cgcgtactcc tgcgtgccgt
    93241 tttgcgcgac cagcgcctgg tttgcctgtt ccagctcagg catcggtacg gcgctgtttt
    93301 gctgctcttg cgaaaccgcg acctcttcca cattggtgtt ttccagcacg tcggatttct
    93361 gcgtattgcc gtaaatgacc gggatatcgc actccgtgca ggcgattttc ggtttcgctt
    93421 cgaagatcac gccgccctga tcgttctcaa tcttgctgat gaaatacggg tcgatcagga
    93481 aaccgccgtt cgccatcacc gcataaccgc gcgcaacctg catcggcgtg aaggaggcgg
    93541 agcccagcgc cagcgattcg gtatgcacga tattctgcgc cgggaagccg aagcgttgca
    93601 gatactccgc cgcatagtcg acgcccatgg cgcgcatggc gcgtaccatc accacgtttt
    93661 tcgactgccc cagcccctgg cgtaaacgaa tcggtccggc gtactgcggc ggagagtttt
    93721 tcggacgcca gtctgaaccg gccccggcgt cccagcggga aatcggcaca tcgttgagca
    93781 tactggcgag cgtcaggcct ttatccattg cggcggtgta gaggaacggt ttgatgttcg
    93841 accccacctg acgcaaagct tgcgtcgcgc ggttaaattt actctgatta aaatcgaaac
    93901 cgccgaccag cgccagtacc gcgccagttt gcgggttaag cgaaaccagc gcggagttca
    93961 cttccggtac ctgcgccagc caccagtcgt tatccacctg acgaacccag atttgctgac
    94021 ctgtctggac gacatcggta actttacgcg gcgtcggccc ctgctgtgta tccgagcggt
    94081 aaggccgcgc ccaacgcatt ccttccatat gtagcgaaac ggacgtaccg tcggcaagcg
    94141 cagcggtcgc ctcttgcgga ttagcgctgg tgaccacggc gggaagcagc ggtccgtagg
    94201 tcggcaacgc tttcaacgta tcggtaattt ttttactgtc ccacgccgtt tcgcccactt
    94261 tccatagcac attcgccggg ccgctataac cgtggcgcat gtcatagtcc agcacgttat
    94321 tacgcaccgc ctgttgcgcg gcctgctgca ctttgcgggt gatggtcgtg taaatacgat
    94381 aaccatcttc ataggcgctt tcgccataac ggttatacat ttcctggcgc accatttccg
    94441 acagataagg cgcggagaag gcgatttccg gcgcgtgata atttgcgtcg ataggttcgc
    94501 tacgggcctg atcgtactgc gcctgagtga tatatccctc gcttaacatt cgtgagagca
    94561 ctacgttacg gcgcgccacc gcccgatcca tcgagtagag cgggttaaag gtagaaggcg
    94621 ctttaggtag cccggcgata accgccattt cgcttaaact aagctggtcg accgtcttac
    94681 caaagtagac ctgtgccgcc gcgccaacgc cataggcgcg gtagccgaga tagatcttgt
    94741 tcagatagag ttcgaggatc tcatttttat tcagcaactg ctcaatacga atcgccagaa
    94801 acgcttcctt gatcttgcgc atcagcgtgc gttcggggct aaggaagaag tttcgcgcca
    94861 gttgctgggt aatggtactt gctccctgcg atgcgtgacc ggagaagagc gcgacgctgg
    94921 ccgcacggaa aatacctacc gggtcaatac cgtgatgctc ataaaagcgg ctatcttcgg
    94981 tggcgataaa ggcgttgatc atttccggcg gaatttgatc gagcgtaacg ggaatacggc
    95041 gtttttcgcc atattgcgcg ataagttcgc catccgcgct gtaaacctgc atcggaattt
    95101 gtaaacgcac atctttcaat gtcgcgacgt caggtagctg cggctcaata tagcgataaa
    95161 ggccataaat cgagcctgct cccagcagga tgcaacatac tgcaaggatc aataaatact
    95221 ttacgaactt cactggagat ttcccattta gtgtcatttg ggcagtttat aaacaaacgc
    95281 gcggtagtat aaaggcaagc cagacgcatt gatatacccg ttaacgcgac gggtgataag
    95341 gagatcgacc gttatggctt ttaaaacctg gcaaatagga ttgcatattc agcagcatga
    95401 agcgctggcc atcgccgtta ttcgcggcgc atcgggctgg tccctgcaac gttggtggcg
    95461 actgccgctg atgaacgcct ccacggcaga gggtacgatt cctgacccgc aatcgctggc
    95521 tcacgtactg cgaccctgga gccgcgagct gccgctacgt caccgtattt atctctcttt
    95581 tcccgcaaat cggacattgc aacgcgcttt tccacatccg ccgatgcgtc tgcgggaacg
    95641 tgagcaagtc gcatggcttt cacaaacgat ggcgcgtgag ctggatatgg atccggactt
    95701 attgcgtttc gactttcagg acgatgcgct gagccccgcg ttcaacgtta ccgccgtgca
    95761 aagcaaagaa atttcagagc tgttaacgct ggcgcaaacg ctcaatgtac gcatcgctgc
    95821 tgtaacgccc gatgcctgcg cgttacagcg cttgctgccg tttatacctt cggggcggca
    95881 atgtctggtc tggcgcgatg aaagccagtg gctgtgggcg acgcgctatg cgtgggggcg
    95941 taaatcggcg cgagaggcga tgacgctgca tgaccttgcc gcgacgttat ccgtcgtgcc
    96001 ggaacatatt tcgttatgcg ccgaaggcga attcgacccc tggcgcgccg ttaccgtccg
    96061 ccaaccgccg gttccgccgg acggttatcg ctttgcgatt gcgctgggtt tagccatggg
    96121 ggagatacgc tgatggcgca ttctgtcaat ttgcttccct ggcggcgcca acattatgta
    96181 gcgcgtctgc ggctgtggtg cgtggtatgg ggcgcgtccc tgctgctgat agcaagcctc
    96241 gcgacgatcg cccggttggt tttttggcag gaggggagga ttaatgaact gctactgacg
    96301 gcggaaaacg gacgcacgac ggcgcttgcg gcgaacatac cgcagttgca gcagcgtcag
    96361 cgacagcaac aggcgcgatt acaacgtcag gcgcagcgtg aactgacgca agcctggcaa
    96421 tctatcttga ctgaccttgc caacctgttg ccagagcagg catggctgac aagcctcaat
    96481 tatcagcaag agacgctaga gctggaaggg ctggcgagaa cgtttgacgc cctgctcacg
    96541 cttgagacat cacttcgtca ctatgtcagt tttccgctaa accgcacggg cgccacgcgg
    96601 caggatgcgc aagggcgctg gcagttccat tatcagttaa cgaggagcgc cgcccgtgaa
    96661 cgcgctcttt gatatctggt acgggatgtc gcgccgtggt cgggtttttt gttggtgtgc
    96721 aggcgtgctg tgcctgacgc tgacggtcgc gttatctgtg ggctatcccg gctggaagac
    96781 gctggatacg caacatgcgc ggttaagcca gcagcgcgag gccgcccggc aacagtggcg
    96841 tcatctgcgc cgtctgagcg tcgcggctga accgcttttc gggcgtacca tcgaaaatcc
    96901 gcgtcctttt tcgccgttag atttccaggc gcctcccttg cgtttgctgc actggcagcc
    96961 atcggcgcag gggggagaaa tggcgctgaa aacgtcctgg gatgcggtgc cgtcgctgtt
    97021 tgtccggttg gccgaaagcg agatgagcgt aagtcggttt tcattgcgta gggagggggc
    97081 ggaattattg ataacgctgc aactggagcg actggcgaat gaaggttagc cgcggtgtat
    97141 tgctctgttt ttgtttgctg acgttgacgg gaatgcgcga tcccttccgc ccgccggaag
    97201 atcgctgccg gatagcggaa ctctcgcagt ggcgatatca gggcgcggtg cgtaaaggcg
    97261 agcgatggac aggcattctt aaagacagcc agcaaaaatg gcggcgagtg gaagaagggc
    97321 agacgctgga aaacggttgg acgattgtcc gcctgacggc ggaagcctta acgttaacga
    97381 ccggtaaaaa ttgtgcgccg ccgcagtggc ggtggttacg tcagggagcg gacaatgaag
    97441 cgatggatag ccataatact gatagtcttg atgcccgccg cgcaggcggg aaaagcggcg
    97501 aaagtgacgc tggtggttga tgacgttcct gtggtgcagg ttttgcaggc tttagccgaa
    97561 caggagcggc agaatctggt ggtgtcgccg gacgtcagcg ggacattatc gctacatctg
    97621 acggatgtgc cgtggaaaca ggcgcttcag acggtggtca atagcgcggg gctggtgctg
    97681 cgtcaggagg ggaatattct ccatgttcat tcacaggcct ggcagaaaga acacagtgcg
    97741 cggcaggatg ccgagcggtt aaggcttcag gctaatttac cgctggaaaa ccgcagcatt
    97801 agcctgcaat acgccgatgc cggcgaactg gcgaaagcgg gcgagaaact cctgagcgcg
    97861 aagggaacca tcatggtaga taagcgcacc aaccgcctgc tgttgcgcga taaccgcgcg
    97921 gccctggcgg agctggaaaa atgggtatcg caaatggatc tgccggtggc gcaggtggag
    97981 ctggcggcgc atatcgtcac cattaacgaa aagagtctac gggaactggg cgtaaagtgg
    98041 acgctggctg acgcgacgca agcgggcgcg gtgggtgacg tgacgacgct ttccagtgat
    98101 ttatccgtcg ccgccgccac ctcacgcgtc gggtttaaca tcgggcgcat taacggacgc
    98161 ctgctggatt tagagctgtc agcgctggaa caaaagcagc agttggatat tatcgccagc
    98221 ccccggctgc tggcttcgca tctacagcca gccagtatca agcaaggcag cgaaattcct
    98281 tatcaggttt ccagcggcga aagcggcgcg acctccgtgg aatttaaaga agcggtactg
    98341 ggaatggagg tgacgcccac cgttttgcaa aaagggcgca tccgcctgaa gttacatatc
    98401 agccagaatg ttcccggtca ggtactacaa caggctgacg gcgaagtgct ggcgatagat
    98461 aaacaggaaa ttgaaacgca ggtagaggta aaaagcggcg agacgctggc gctgggcggc
    98521 attttttcgc gaaaaaataa atcgggtagc gatagcgtgc cgctgttggg ggatattccc
    98581 tggcttggtc agctcttccg ccatgacggc aaagaggacg agcgacgcga attagtggtg
    98641 tttatcaccc ccagactggt ggcgacagaa taatttatgc ataaaaaagc gctgtttttg
    98701 cactgaacgc atctgcggga tttgacgtgc ggatgtattt agcatacaag gagtaccgat
    98761 ttgagagtcg tgcttttcgt tgcttacgca ttgattaatg cgctttgcct tgccgaaggt
    98821 gtgcataaga ccgatgataa acggctgaat gtccgctgat gcagacgtat tggttctgcg
    98881 gattgcgcac aattgtttga aagtagagca atttgtaggc cggatatgtt gttctggtcg
    98941 ccattcggca acgctaactc gggttttgca acaatcaggc ttggtgattt attcagttgc
    99001 caaacccgct tgagtattga gataattttc agtctgactc tcgcaatatc ttatgaggtt
    99061 tcagttcatg tcctgctgcg ctgggtgtct gtgaagcggg tttaccatta acgaatagtc
    99121 ttagtagtac cgaaaaaatg gcagagaaac gcaatatctt tctggttggg cctatgggtg
    99181 ccggaaaaag cactattggg cgccagttag ctcaacaact caatatggaa ttttacgatt
    99241 ctgatcaaga gattgagaaa cgaaccggag ctgatgtggg ctgggtcttc gatgttgaag
    99301 gtgaagacgg cttccgtaat cgtgaagaaa aagttatcaa cgaattgacg gaaaaacagg
    99361 gtattgtgct ggcaaccggc ggtggctctg taaaatcgcg tgaaacgcgt aaccgtctct
    99421 ccgcgcgtgg cgtcgtggtc taccttgaaa cgaccatcga aaaacaactg gcgcgcacgc
    99481 agcgtgataa aaaacgcccg ctgttgcagg ttgaagcacc gcctcgcgaa gttctggaag
    99541 cgctggctaa cgaacgcaat ccgctgtacg aagagattgc cgacgtcacc attcgcaccg
    99601 acgatcaaag cgctaaggtt gtggcaaacc agattattca tatgctggaa agcaactaat
    99661 tcaagcagaa tacgctgggt aagcgggcac aagtaactaa ggtggatgtc gcgtcatgga
    99721 gaggattaca gtcactctcg gggaacgtag ttacccgatc accatcgcgg ctggtttgtt
    99781 taacgaacca gcttcattct tgccgctgaa atcaggcgat caggtcatgt tagtgaccaa
    99841 cgaaaccctg gcgccgcttt atctggacaa ggttcgcggc gtactcgaac gggcgggcgt
    99901 taacgtagac agcgtgattc ttcctgacgg cgagcagtat aagagcctga cggtgctgga
    99961 tacggtgttt acggcgttac tgaaaaaacc gcatggtcgt gataccacgc tggtcgcgct
   100021 tggcggcggc gtgattggcg atcttaccgg ttttgcggcg gccagctacc agcgaggcgt
   100081 tcgtttcatc caggtgccaa ctaccttact gtcgcaggtt gattcttccg tgggcgggaa
   100141 gaccgccgtc aaccatcccc ttggcaaaaa catgattggc gcgttttacc aacccgcttc
   100201 tgtggttgtc gatcttgatt gcctgaaaac gcttcccgca cgcgaactgg catcgggact
   100261 ggcagaggtg atcaaatacg gcattatact cgacgcagac ttcttcacct ggcttgaggg
   100321 taatctggat gcgctattgc gtctggacgg cccggcgatg gcgtactgta ttcgtcgttg
   100381 ttgcgagctg aaagccgaag ttgttgccgc cgacgagcgt gaagcgggct tacgtgcttt
   100441 actgaatctt gggcatacct ttggccacgc cattgaagcg gaaatgggat atggcaattg
   100501 gttacatggt gaagccgttg ccgcaggtat agtgatggct gcgcgcgcat ccgagcgttt
   100561 ggggcagttc agttctgctg atacgcagcg catcatcgcg ctactcgaac gggccgggtt
   100621 gccagtcaat ggcccttgcg agatgtccgc gcaggactat ttgccgcaca tgctgcgaga
   100681 taaaaaagtg ttagcggggg agctgcgttt agtgcttccg ctgaccatag ggaaaagtga
   100741 agtgcgcggc ggagtgtcgc acgaagtcgt tcttagcgcg attgctgact gtcagcaggc
   100801 gtaacaacaa gaaaggtcag actgatattg cgtagctgtc agtcttttag cttcaggtta
   100861 tgtgcaatgt cgtaagcatt aacctttgag tggggtgtta aatggatgaa ttcaaaccag
   100921 aagacgagct gaaacccgat cccagcgatc gtcgtactgg tcgttctcgt caatcttcag
   100981 aacgcgataa tgagccgcag atcaactttg atgacgttga tctggatgcc gacgatcgcc
   101041 gtccgacgcg tacgcgtaaa gcgcgtagtg aagaacctga agttgaagaa gagtacgaat
   101101 ccgatgaaga cgatacggtg gacgaagagc gtgttgaacg ccgtccacgt aagcgtaaaa
   101161 aagcggccca taagccagcc tctcgtcagt acatgatgat gggcgttggc gtactggtgc
   101221 tgctgctgtt gattatcggt atcggctccg cgctgaaagc cccctcaacg tcttccagcg
   101281 agccgtcggc ctctggcgaa aagagtatcg atctttccgg taacgccgcc gatcaggcga
   101341 atgcgaccca gcctgcgccg ggcgccacct ccgcagaaca aaccgcgggc aatacgtcgc
   101401 aggatatttc gttgccgccg atttcttcaa cgccgatgca gggacagtcg cctgtggtcg
   101461 ctgacggtca gcagcgcgtg gaagtgcagg gcgatctgaa taatgcgctg acgcagaatc
   101521 cagagcagat gaacaatgtt gcggtgaact ctacgttgcc gacagagcct gcaaccgtcg
   101581 cgccagttcg caatggcagc acgacgcgtc aggcggcggt tagcgaacct gccgagcgtc
   101641 ataccacgcg tccggaacgt aaacaggccg tcattgaact taagaaaccg cagaccacgg
   101701 cgaaaaccac cactgcggaa ccgaagaaac cggtcgcgcc agtgaaacgc acggaaccgg
   101761 cagcgccagc cgcgacgccg aaagcgacca ccacgacggc tgcgccgcaa gcgacggcaa
   101821 gcgctgcgcc ggtacaaacc gcgaagccgg cgcaagcctc gacgacgcct gtcgcaggcg
   101881 gcgggaaaag cgccggcaac gttggcgcat taaagagcgc gccatccagc cactacacat
   101941 tgcagctcag tagttcttca aattacgaca acctgaacgg ttgggcgaag aaagagaacc
   102001 tgaaaaatta tgtggtatac gagacgacgc gtaatggaca accgtggtat gtgctggtaa
   102061 cggggatgta tgcttcgaaa gaagatgcta aacgtgcggt gtccacctta cctgccgatg
   102121 tgcaggcgaa aaacccgtgg gcaaaaccgt tgcatcaggt tcaggccgat ctgaaataat
   102181 ccaggctgtg tcctgcaatt gcctgtgagt gtcgctgaca gctatttttt ttcaggacag
   102241 gcgcgagggg cgcatttgct accgtcaaat gcgccgtaaa gcaacgcggc acagcctaaa
   102301 gcgcaggatg ctgtcggagc tttctccaca gccggagaag gtgtaattag ttagtcagca
   102361 tgaaaaaaaa tcgcgctttt ttgaagtggg cagggggaaa ataccctctg cttgatgata
   102421 tcaaacgaca tttgccaaaa ggcgagtgcc ttgtcgaacc ttttgtgggt gccggatcgg
   102481 tgtttcttaa caccgacttt tctcgttata tcctcgccga tatcaacagc gaccttatta
   102541 gcctctataa catcgtgaag ttacgtactg acgagtatgt acaggcttcg cgcgagctgt
   102601 ttatgcctga aactaaccag gctgaggtct attaccaact ccgtgaggag ttcaacacct
   102661 gccaggaccc ctttcgtcgg gcggtactgt ttttatatct gaaccgctac ggttataacg
   102721 gactctgccg ctataacttg cgcggggaat ttaatgtacc gtttggtcgt tataaaagac
   102781 cttacttccc ggaagcggag ttgtaccact ttgcagaaaa agcgcagaat gcgttctttt
   102841 actgtgagtc atacgcagac agtatggcgc gtgcggacaa gtcgtcggtg gtctattgcg
   102901 atccgcctta tgcgccgttg tccgccacgg ctaacttcac agcgtatcac accaatagtt
   102961 ttagcctgac gcaacaagcg catctggcgg aaatcgctga gaatctggtc agtaaccgga
   103021 taccggtgct catttccaac catgatacgg cgctcacacg cgagtggtat caactcgcaa
   103081 aattgcatgt cgtcaaagtt agacgcagta taagcagcaa cggcggcaca cgtaaaaagg
   103141 tggacgaact gctggctctg taccaaccag gagtcgcaac gcctgcaaga aaataattct
   103201 caaggagaag cggatgaaac agtatttgat tgccccctca attctgtcgg ctgattttgc
   103261 tcgcctgggt gaagacaccg ccaaagcgct ggctgccggt gctgatgttg tacactttga
   103321 cgtcatggat aatcactatg tgccgaacct gactatcggc tcgatggtgc tgaaatccct
   103381 gcgtcagtac ggtattaccg cgcctattga tgtccacctg atggtcaagc cggttgaccg
   103441 tatcgtgccc gactttgccg ccgctggcgc gagcatcatt acctttcacc cggaagcctc
   103501 cgaacatgtt gaccgcacgc tacagctgat taaagagcac ggctgtaaag cggggctggt
   103561 attcaacccg gcaacgtcgc tcagttatct cgattacgtc atggacaaac tggatgtgat
   103621 cctgctgatg tccgtgaacc caggcttcgg cggccagtct tttattccgc agacgctgga
   103681 taaactgcgc gaagtgcgtc gccgcattga tgcgtccggt tacgacattc gcctggaagt
   103741 ggacggcggc gtgaaggtga acaatatcgg cgagatcgcc gcagctggtg cggacatgtt
   103801 tgttgcgggg tcggcaattt tcgataaacc cgactacaaa aaagtgattg atgaaatgcg
   103861 cagtgagctg gcaaaggtaa gtcatgaata agttgcagaa tattcggggc gtcgcctttg
   103921 atcttgacgg tacgctggtg gatagcgcgc cgggtcttgc cgcggcggtg gatatggcgc
   103981 tgtatgcgct ggaactgccg gtcgcgggcg aggagcgcgt gattacctgg attggtaacg
   104041 gcgcagacgt attgatggaa cgcgcgctga cctgggctag ccaagagcgc gccacgctgc
   104101 gtaagactat ggggaaaccg cccgttgatg aagatattcc tgccgaggaa caggtacgca
   104161 ttctgcgtaa actgttcgac aggtattatg gcgaagtggc ggaagagggc acctttttat
   104221 ttccgcatgt cgccgacacg ctgggcgcgc tgcacgccag cggattgtca ttaggtctgg
   104281 tgacgaataa gccgacgccg ttcgtcgcgc cgttgctgga atcgcttgat atcgccaaat
   104341 actttagcgt ggttatcggc ggcgatgatg tgcaaaataa gaagccgcat ccagagccgt
   104401 tgttgctggt ggcaagccga ctgggcatga cgccggagca gatgcttttt gtcggcgatt
   104461 cgcgtaatga tattcaggcc gcaaaagcgg cgggctgccc ttcggttggc ctgacatacg
   104521 gctacaatta tggcgaagtg atcgccctta gcgagccgga cgtcatttat gacagtttta
   104581 acgatctttt gcccgcactt gggcttccgc atagcgataa ccaggaaata aaaaatgact
   104641 aagcccatcg tttttagtgg cgcacagccc tcaggtgaat tgaccattgg caactatatg
   104701 ggggcattgc gtcagtgggt aaacatgcag gatgactatc attgcatcta ctgcatcgta
   104761 gaccaacatg ctattaccgt acgtcaggac gcgcagcagc tacgtaaagc gacgctggat
   104821 acgctggcgc tgtacttggc atgtggtatt gatcctgaaa agagcactat tttcgttcag
   104881 tcccatgtgc cggaacatgc gcagcttggc tgggcgctga actgctatac ctatttcggc
   104941 gagctgagcc gtatgacgca gtttaaagat aaatctgcgc gctatgcgga aaatattaac
   105001 gccggcctgt ttgattaccc ggtgctgatg gcggcagaca tcctgctgta ccaaaccaat
   105061 ctggtgccgg taggcgaaga tcagaagcag catctggaac tgagccgcga tatcgcccag
   105121 cgtttcaacg ggctgtatgg cgatattttc aaagtaccgg aaccgtttat tccaaaatcc
   105181 ggtgcgcgcg tgatgtcgtt gctggagccg acgaagaaaa tgtccaaatc ggacgataac
   105241 cgtaataacg taatcggcct gttggaagat ccgaaatcgg tagtgaagaa aatcaaacga
   105301 gcggtcactg actccgacga gccgccggta gtgcgttatg atgtgaaaga gaaagcgggt
   105361 gtctctaacc tgctggatat cctttccgcc gtgaccggtc agagcattcc tgagctggaa
   105421 aaacagtttg aaggtaaaat gtatggccat ttgaaaggcg aagtggcgga ggcggtttcc
   105481 ggaatgctgt ctgagttgca ggagcgctat caccgtttcc gcaacgacga agcgttcttg
   105541 cagaaggtga tgaaagacgg ggcggaaaaa gccagcgcac gtgcggccga aacgctgaaa
   105601 gccgtttacg aagccattgg ctttgtggcg aaaccgtaac ggtaattgct tgcccgatgg
   105661 cgctagctta tcgggcctac caacgaacgt aagttggaca aggcacctgt gccatactgt
   105721 ttatcagacc tgtaaaaaaa ccgggaaatc ccggtttttt tgtatctgcg cagtcgtttc
   105781 tattattgat cggcagccgg gccgcaaccg ccaataattt tagaaataga aattgcaggg
   105841 tgcagcaaat aatcgtagct gcagttattt tttttgtttt cgatatgacc agtacaggcg
   105901 gtaagcgtcg ccagaacccc tgccacaacg gcaattttta caaatttaaa catgtcaaaa
   105961 tccttgttga taaaacgaat actactggtg gaataaatat aagatctatt tagcgtatag
   106021 tacgatagca attaataaac aatgcaggta gtccaaataa ggactttatc tttaccaggg
   106081 aatatgattt aaaaaaggcc gcttaataat aagcggccta tattagtgtt atataatgtc
   106141 gtttatttaa cgaaatgttt tcttaacgtt aagcataaag cctttatcgc tgataccgtc
   106201 ttccttccac tggtatgcat ccagatgtag cgcggtatca ttgctgctat atttcacgcc
   106261 gatggttgcc aggccattaa tgccgccgcc tttttgaccg tcatccacgc cgaacgattg
   106321 acccgccgca ccctgtaatg acgctgtacg ctggctcttg ctgtagctca ggttcgggcc
   106381 gccttccagg gtagcggtgg cgctccagcc gtctttcccg gcgtaatcca gcttcatacc
   106441 cacaatggaa tccaccgctg tttcgctgcc agagttcatc gacaggttaa aatcgccagc
   106501 gttgcgctct ttgtagccat cttccatggt atgacggaat ttcaccccgg catacggcgt
   106561 cactttcagc gcatcgtcca tcagggagaa ggttttcgcc ccctcgctac ggaactccat
   106621 gtactgctga cgcgcatcgg aatcggcaat tttgttaaca tcgccatagg cgacagaacg
   106681 gctgctgtcg aggttgtgta cgtcataacg caggctgtta ttccacgcca gaccttcatc
   106741 aaacgccatg ctgtgcttca gaccaaagaa ctggctgtag ccgccggtca ggccgttgtc
   106801 gcccgctttt tgcgaaccat cgccgtccag acgggcgata ccgtattcca gcgtcaggtt
   106861 ctggtttgcg gttaagtcca gtttctgacg cagcgccagc atgtcgtact gggtgtcgtt
   106921 gcccagctcg gcgcgcgggt cgcctttcgc caccacgtta aacgccaggc cgtctttaat
   106981 ctgcggcgcg gcgtcggcca gcatgttgaa gcggttgctt aacacccggg cttcacggaa
   107041 taccgtagtg gcctggctgc cgcttacctg tttcagcgca ctgttgagtt cggcggtggt
   107101 gcctacgtta aggctggtgt acagctcgtt gttggtgtag ccagcgtcca gcgcctgcgc
   107161 cacgtcagac acgctaccgt cggttgccac atcggcgtag gcgtttttgg tcatggtgac
   107221 gtcaacgttg ccgtcgctgt cctgactgcc ctgggcgttc cacaccacgc tggtggactg
   107281 gatagcggaa gcgtcggtga ggttgctgcc ctccaccacg ttgtcaaagc tgacggtggt
   107341 gtcggcggtg cctgcggtga agccggtatt gatacccacg ccttccatgc tggcgttgct
   107401 gaccttaagc tggcctgcgc tgccgtcggc gttcgtgcca accacgtagc cgttcaggtt
   107461 gttggacgcg ccggacgtgt cgccggcggc gaagccggag gtcgtgttgc tgccgggttc
   107521 aacaggcgtt tccggcaacg tatagtcggc ataatgcgcc tcgtcgctgt tgccgttatt
   107581 accgtttgtc ccttcgacgt taacgctgtc accctgttta ataataccgg aacccgttac
   107641 gccatcggca atgactaccg tcccgttatt aaccacatgc cccgcacccg ccacgctaaa
   107701 cgcgtaagag ttattggcgt aaatattaat tgtaccgttg ttctcaatga cagcattagc
   107761 ggtagcattt ttatccagcg ccatcgcgac catgcctgtg tcggtggtgc cttctgtacc
   107821 taaattgatc gtattgttat tgaccagttg tgcatttttg ccgccataca tgccgtaagc
   107881 gttattaccg ctgatattca tggtgccgtc gttgaccgct acgtaattgt tataggcgga
   107941 gaaatcgacg gcgcggccat tatccgcatc gtaattgatt acgccgtttg actggttcca
   108001 gaagaaagcg tgtttatccg gggcattacc tgcgccgccc cccgcataag caagcaccgc
   108061 agtagtggca tttaccgtac cgtcattgat aaatgccgct cccgcgcccc aatagttaat
   108121 cgcgccctta ttggaggttg ccgtaagctc catcgtcccg gtgttgtaca gcgttccgtt
   108181 attcgcattc aggtgaatgg catttttgtt gttatcaagg attaacgtac cggtattaaa
   108241 gaattgcgcg aaatcattga tttccagcat ggacgcattt ttagcgtcag tcgcggagcc
   108301 aagatagaac gtaccgtcgt taatgattgc actgttagcg ccagtcactt ttgcgccgga
   108361 agccatggtg ccatccgtgc gttagttaat acgccgttgg tcgtcaggct acggctgtca
   108421 atggtgccat tattaacgat atcgccgcca ttttgcgtca gcgcaccgtt tatgacgccg
   108481 tcattgacaa ggttgccgga taccgtggtg ttgctattga taacgccgct gtcgttgttg
   108541 gtcagcgtgc cgctatccag gacggtaatg gactcgccgc tgaccactcc ggtattatta
   108601 acgtctcctg tcacaatcgc tttattacca agcgttgtac ttgttccggc atcggcaatc
   108661 gtagcgccgt ctgtgtaagg gatagaaacg tcactgtttg ttggattgta ctcgtcgctg
   108721 tcctggcaat cgtcgccaaa acagacggtg ccgtagttaa caatcaggct attgccgtcg
   108781 gtcaggaaag gcttgccgta atcggcataa atattgattt tgcctgtggt atcgttgaca
   108841 acggttccgc cgttgagcgc cgccatgcct accagttgat tcgggtcggt cccttcaacg
   108901 cccgcatcag cggtcagatt aattaccccc tggttaatgg cggtaccgcc gttaagcgcc
   108961 atcatgccga acccggcgtt attgacgtta atggtgccgg tgttggtggc ggtggcatcg
   109021 ccataaccgc tgtcggtggt gcctgcgacc atcgcggcgc tggtgacata aagtttcggt
   109081 ggcgtccagt aagttttgtc ggtgatgtta ttttcatcat ccagcgtcgg gacaaagccg
   109141 tccaggtaga tatcaccagc gttgagcgcc gtgcctttgc tggcggatac gccgtatacc
   109201 cctgcgccct gcaaatatat ggtggcgccg gcgtcgttac tcacctcgcc gtagtcctct
   109261 gccagcatgg cgtacagggt atttttgtac cagattagtg ggaagttgcc cgcgccggta
   109321 tttgaaaacg gagttaatga tgaaactaag gtgattgtcc cttccgcttc attattaacg
   109381 gtggaaccct ggccgttagc cgcggctatc gcattacggc tggacgtccc tgttgtggca
   109441 tacgcggtaa tcttgccgct gttttgtgcc tgtgcgccgc tatccgccag taataaagcg
   109501 acggcgccat cgtcaacgac agtgccctga ttattgattg aggagccctc gccgctggcg
   109561 gttaacaggg cctgcgtcat gtaataatta gaaagaataa ccgtttcatt gatattaacc
   109621 gttgagtttt gatctaacgt taagttgccg ccatttctca cattcgccag cgtcaccgcg
   109681 ccgccgggga cggtggcaat attgagcgtg gattcaccgc ttagcgttac gctactgtct
   109741 ccgctgatgt ttatactggt aacggctgat tcgaggccgt cagcatcttc ggtgtagttg
   109801 atattaatac cgccggctaa gtccacggta ttgccatcac ctgccacatc aaggccaacg
   109861 gtattcagat attgttcgtc cacgttactc atatcgctga cgttaatatt gagcgtgccg
   109921 ctcaggtcca ccgcattatt gctgccgctg atagacatcc ccataagggt atcgctgctg
   109981 ccggccatca cgctgtcttt gtcatagtcg ccgttgaccg tgacgctgcc gataatattc
   110041 agcgtgttgt tattccccgt catgtcgagg cccgtcgcgc cacgataaac gttatccccg
   110101 tcctctgttg cggtgacatt aatatcgcca tccagcgtcg cttgcgacgc attgccgctt
   110161 accagcgcgc cggtgccgtt aaggctgatg ttaatattcc ccttgttttt gaaggtgttt
   110221 tgttcgcctg cgaccacaaa ccccactgag tctacatcac gcacggtggc gttgccggta
   110281 tttttggctt catttccggc gccgtaggtg atgatgccca tcgcgccgtc ggtgaccagc
   110341 agatcgcccg cctgggtcag gctgctattg tcgccattaa taatcgccgc cgcagagcct
   110401 gcgccatcaa cggcgatatc gccggtattg gcgatacggg cgtcgtcgcc gtcaattcgc
   110461 gtaccaatgg cgccgccgga aatagtctga ttaccttcat tgataatgag cgcattgtcg
   110521 ccgtcgatat acagcgccgt tgagcccgtg ccgctgacgg tggtgtcccc ggcgttatcg
   110581 ataaccgcgt tatcgccggt gatgtgagca ccggtgccgc catcggtgat ggtcatatca
   110641 ccgtcattgt tgacgcgggc gttattgccg tcaatgacgg tgccggtgga gcctgtgccg
   110701 ttgatggtgg aggtaccagt attcttaatc gtggcgttgt cgccgtcgat gatgatggcg
   110761 gtgccgccgc cgctcacggc aatgtcaccg gcgaaattgg tggtggttcc gttgccggaa
   110821 atcagcgcgc cggtggcgtt gtccaccgtt gagtggcccg aaatggtgtt ggtggtgcca
   110881 tcgccagtga tcaccatgcc gatggcgccg tcggtcacac tggaaccccc ggtgagcgtg
   110941 ttgacggttc gattgccgga aataatcacg ccggtgcgat cctggccgct gatatccatg
   111001 ccgcgatcgg aggtatgcga ttcgccgtcg ccgctgataa cggtggtttt atcgtcggca
   111061 aggatcagat agccccggct gtcatacttc cagtagagac cattttcctg ggtgccttca
   111121 atcacggcgg cattagcgtc ggtcacgtcc caaccggtga cgttcagcgt tttgccgccc
   111181 aggggggtga gctgccactg gttgttctgt tctgaataat tccacacggc accctcgaga
   111241 acgctgccgc tatccagttt gaagctatcg aaggccaggg tgtctttgcc tttatcgatg
   111301 gtgacgccgt tgctgaaggt tataacagag tcatccgggg gcgtgtcgtc gtcatcgggc
   111361 ggggtcacat cgtcatcgcc gctatcgtcg ggcggggtta catcgtcatc gccgctatcg
   111421 tcgggcgggg tgacattgcc gccatcgtcg ggcgtagggg gaatataaga atgagtagaa
   111481 tctccgccac cgttattttc aacgccaata accacacccg cgaccaatgc ggcaacgccg
   111541 ccagcaaccc agccccagtg attatcattt tcaggtaatg tagcaaggca ggtcggtgag
   111601 agttttgcgc gtttttcttt aggcagggag gcgatattac tgggacattc tttttcatca
   111661 tcgttattct ctgcggcgat ggccggaatg taataacttt gcagcgttaa agcgatagcg
   111721 atagaaataa gttttttctt ttgcatagag ttcatcctta attaatattt ccttgcgtac
   111781 taaacatatg cggatagcga tacaggcaat gatgaaatgg ccagaagaaa attatgattt
   111841 agtgtttatt ttatcacccg ataaccaggt caggtcaaat tgaaggctta acgatattat
   111901 ttattgggtg aatgaataac gggtgaattt gacgaatgaa agggttttta cgcaatataa
   111961 ttgctattta aattcgtttg g
//
LOCUS       DAJVKX010000002        84345 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000002 DAJVKX010000000
VERSION     DAJVKX010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 84345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84345
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.002"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            87..440
                     /locus_tag="OPY25_000095"
     CDS             87..440
                     /locus_tag="OPY25_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaA/YiaB family protein"
                     /protein_id="HCS0925830.1"
                     /translation="MDDHVARRKRIFGLGMLVVGAVVYLVGLWPGCHTLSEKGYFFAA
                     IVMCGFPVLIRQEHTGNDRLLSRCKSLLLLGIGMVAVGVFNLALAGALKILCLVALGV
                     SIYGTDLYASYSDDE"
     gene            complement(463..1457)
                     /locus_tag="OPY25_000096"
                     /pseudo
     CDS             complement(463..1457)
                     /locus_tag="OPY25_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462558.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
     gene            1623..1925
                     /locus_tag="OPY25_000097"
     CDS             1623..1925
                     /locus_tag="OPY25_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0925831.1"
                     /translation="MIMKYFCTVMIAIALVGCTATPPPTQKAQQSKVSPTRTLDMEAL
                     CKAQAAQRYNTGAQKIAVTGFEQFQGSYEMRGNTFRKESFVCSFDADGQFLHLSMR"
     gene            2064..2975
                     /gene="glyQ"
                     /locus_tag="OPY25_000098"
     CDS             2064..2975
                     /gene="glyQ"
                     /locus_tag="OPY25_000098"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCS0925832.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPENIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKLVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            2985..5054
                     /gene="glyS"
                     /locus_tag="OPY25_000099"
     CDS             2985..5054
                     /gene="glyS"
                     /locus_tag="OPY25_000099"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCS0925833.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAYVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNASVVDDVIDFMLGRFRAWYQDEGYSVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDK
                     LQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQV
                     ADISLLQ"
     gene            5651..5872
                     /locus_tag="OPY25_000100"
     CDS             5651..5872
                     /locus_tag="OPY25_000100"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCS0925834.1"
                     /translation="MSRKGNCLDNACAEFFFGTLKSESFYTSKFKDIDELKIAIEDYI
                     RYYNTRRISLRFNGLSPVEYRLKSYPGRN"
     gene            6014..6481
                     /locus_tag="OPY25_000101"
     CDS             6014..6481
                     /locus_tag="OPY25_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0925835.1"
                     /translation="MKIRRFSNGDEISLFRVFFSSVHTIASHYYTREQIDAWAPADID
                     LERWANHIKELQPFVVELDGEIAGYADVQPNGYIDHFFVSGTYSRQGVGTLLMNCIHE
                     EARQRGISELTSNVSKAAEVFFLRHGFHIVERGFPICRGVTLQNALMRKCLAK"
     gene            6659..6946
                     /locus_tag="OPY25_000102"
     CDS             6659..6946
                     /locus_tag="OPY25_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCS0925836.1"
                     /translation="MLYKGCLMKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILET
                     ACRAAENVILDRRVFNFNDEQYEEFINLLDAPVADDPVIEKLLARKPQWDV"
     gene            6934..7419
                     /locus_tag="OPY25_000103"
     CDS             6934..7419
                     /locus_tag="OPY25_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0925837.1"
                     /translation="MGRVTAPEPLSAFHQVAEFVSGEAVLDDWLKQKGLKNQALGAAR
                     TFVVCKKDTKQVAGFYSLATGSVNHTEATGNLRRNMPDPIPVIILARLAVDLSFHGKG
                     LGADLLHDAVLRCYRVAENIGVRAIMVHALTEDAKNFYIHHGFKSSQTQQRTLFLRLP
                     Q"
     gene            complement(7790..8329)
                     /gene="cueP"
                     /locus_tag="OPY25_000104"
     CDS             complement(7790..8329)
                     /gene="cueP"
                     /locus_tag="OPY25_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-binding periplasmic metallochaperone
                     CueP"
                     /protein_id="HCS0925838.1"
                     /translation="MSKSSWLLLLGLCASGSALAASSESAFLAQHGLAGKTVEQIVDT
                     IDQTPQSRPLPYSASITSTELKLSDGEQIYTLPLGDKFYLSFAPYEWRTHPCFNHSLS
                     GCQGEMPNKPFTVKVTDSKGAVIVQKEMQSYRNGFIGVWLPRNMEGTLEVSYNGKTAS
                     HAIATRDDSQTCLTELPLR"
     gene            complement(8505..8717)
                     /gene="cspA"
                     /locus_tag="OPY25_000105"
     CDS             complement(8505..8717)
                     /gene="cspA"
                     /locus_tag="OPY25_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HCS0925839.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(8930..9295)
                     /locus_tag="OPY25_000106"
     CDS             complement(8930..9295)
                     /locus_tag="OPY25_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HCS0925840.1"
                     /translation="MEYKDPMFELLSSLEQIVFKDETRKITLTQKPNPFTEFEQLRRG
                     TGLKTDEFARALGVTVAMVQEWESKREKPTPAELKLMRLIQANPRLSKQLMEQFLPLS
                     VLTVLRKGRFPRPITGLEK"
     gene            9734..10444
                     /locus_tag="OPY25_000107"
     CDS             9734..10444
                     /locus_tag="OPY25_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HCS0925841.1"
                     /translation="MATGKSCSRWFAPVVALLMVFSLSGCFDKEGDQRKAFVDFLQNT
                     AMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYMTQREPLRQANGSLGVLAQQLQNAKLQADAAHGALKQADDLKPVFDQVYKKVVTVP
                     ADALQPLIPAAQIFTQQLVQVGDYIAQQGEQVSFVANGIQFPTSQQASQYNALIGPLA
                     SQHQAFNQAWTAAVNATQ"
     gene            complement(10494..11468)
                     /gene="ghrB"
                     /locus_tag="OPY25_000108"
     CDS             complement(10494..11468)
                     /gene="ghrB"
                     /locus_tag="OPY25_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HCS0925842.1"
                     /translation="MKPSIILYKTLPDDLLHRLEAHFTVTQVPNLHPETVARHAQAFA
                     SAQGLLGTSETVNRALLEKMPALRAASTISVGYDNVEVDALTARKIVLMHTPAVLTET
                     VADTVMALMLATARRVVDVAERVKAGEWTESIGPAWFGVDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFTMPVLYHARRRHQEAEDRFNARYCDLDTLLQEADFVCVILPLTAETRHLF
                     GATQFARMKSSAIFINAGRGPVVDENALIAALQNGEIYAAGLDVFEQEPLSVDSPLLN
                     MSNVVAVPHIGSATHETRYNMMACAVDNLIDALQGKIEKNCVNPQAAG"
     gene            complement(11687..12349)
                     /locus_tag="OPY25_000109"
     CDS             complement(11687..12349)
                     /locus_tag="OPY25_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HCS0925843.1"
                     /translation="MKKRVFVIAAIVSGALAVSGCTTNPYTGEREAGKSGIGAGIGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVVGYTDSTGSHDL
                     NMRLSQQRADSVASSLITQGVDASRIRTSGMGPANPIASNSTAEGKAQNRRVEITLSP
                     LQ"
     gene            12502..14835
                     /locus_tag="OPY25_000110"
     CDS             12502..14835
                     /locus_tag="OPY25_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin guanine dinucleotide-containing
                     S/N-oxide reductase"
                     /protein_id="HCS0925844.1"
                     /translation="MTHAPSRHSVLTAAHWGPVRVETDGERIFASYGELPTAHQNSLQ
                     TVVHDQVHSKTRVRFPMVRKGFLASPDKPQGIRGQDEFVRVSWDDALDLIHAQHKRIR
                     ESYGPSSIFAGSYGWRSNGVLHKAATLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGNEVYQQQTSWPVVLEHSEVVVLWSANPLNTLKIAWNASDEQGLDYFAALRQSGKRL
                     ICIDPMRSESVDFFGDKMEWIAPHMGTDVALMLGIAHTLVENGWQDEAFLARCTTGYD
                     RFADYLLGTTDGTAKTAEWAAEICGVSAVKIRELAEIFHHNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGFSYHFANGGNPTRRAAVLASIQGSIPGGVDAVDK
                     IPVARIVEALENPGGFYQHNGMDRRFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSYERNDLTMTGDYSNQHLAPMKQVVSPRWEARNDF
                     DVFAELSERWEAGGYARFTEGKSELAWLETFYNIAAQRGASQGVTLPPFAAFWQANRL
                     LEMPENPANAQFVRFADFRRDPDNHPLKTASGKIEIYSARIASYGYADCPGHPMWLAP
                     DEWHGNADAGQVQLLSAHPAHRLHSQLNYSSLRERYAVAGREPVTIHPQDATTRGIVD
                     GDTVRVWNHRGQVLAGAVVTDGIRPGVICIHEGAWPDPEPTAGGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALVWFEKYTGPALPLTAFDPPANS"
     gene            complement(14804..15244)
                     /locus_tag="OPY25_000111"
     CDS             complement(14804..15244)
                     /locus_tag="OPY25_000111"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCS0925845.1"
                     /translation="MIRKSQSEDMASILALWMKSTIYAHPFIEERYWHESEAIVRDVY
                     LPAAQTWVWEENGQLKGFVSVLEARFVGALFVAPDALRHGIGKALLEYVQQRFPLLSL
                     EVYQKNQSAVNFYHALGFRIEDSAWQEDTSHPTWIMSWQADQTP"
     gene            complement(15222..15803)
                     /gene="tag"
                     /locus_tag="OPY25_000112"
     CDS             complement(15222..15803)
                     /gene="tag"
                     /locus_tag="OPY25_000112"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCS0925846.1"
                     /translation="MQRCDWVSQDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPIRIAAMQEEDVERLLQNTGIIRHRGKIQAIISNARAW
                     LAMEQNGESFADFVWSFVDGQPQITQAASLDKIPTSTPASDALAKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHITGCFCHPGEKHDSQIPE"
     gene            15960..16664
                     /locus_tag="OPY25_000113"
     CDS             15960..16664
                     /locus_tag="OPY25_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HCS0925847.1"
                     /translation="MIVRKRRGRRTLRCLAGLMACSFFINTTYAWQQEYIAEAAPGHT
                     TERYTWDSDHQPNYNDILAERIQSTQNTVGPVLSLADETPLDATSGISMGWNFSLSRR
                     VTTGPVAALHYDGSTSSMYNEYGDSATTLALTDPLWHASVSTLGWRVNSQFGDVRPWA
                     QISYNQQFGENIWKAQSGLSRMTAGNQAGNWLDVTVGADVLLNPHLAAYAAFSQAENS
                     ATDSDYLYTLGVSARF"
     gene            16895..18526
                     /gene="eptB"
                     /locus_tag="OPY25_000114"
     CDS             16895..18526
                     /gene="eptB"
                     /locus_tag="OPY25_000114"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HCS0925848.1"
                     /translation="MRYIKSMTQQKLSFLLALYIGLFMNCAVFYRRFGSYAQEFTIWK
                     GLSAVVELGATVLVTFFLLRLLSLFGRRVWRVLATLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLHFVLWLIAVSVLPLIFIWSNHCRYTLLRQLRTPGQRFRS
                     AAVVILAGVMVWAPIRLLDVQQKKFERATGIDLPSYGGVVANSYLPSNWLSALGLYAW
                     AQVDESSDNNSLINPARKFTYVAPKDGDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     SLRCMFVREGGADNNPQRTLKEQNVFAVLKQLGFSSDLYAMQSEMWFYSNTMADNISY
                     REQIGAEPRNRGKTVDDMLLIDEMQNSLAQNPEGKHLIILHTKGSHFNYTQRYPRSYA
                     QWKPECIGVDSGCTKAQMINSYDNSVTYVDHFITSVFDQLRDKKAIVFYAADHGESIN
                     EREHLHGTPRNMAPPEQFRVPMLVWMSDKYLASPQHAQMSAHLKQQAEIKVPRRHVEL
                     YDTIMGCLGYTSPNGGINQNNNWCHIPDAQKVAAK"
     gene            18617..18693
                     /locus_tag="OPY25_000115"
     tRNA            18617..18693
                     /locus_tag="OPY25_000115"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18651..18653,aa:Pro,seq:cgg)
     gene            18729..18847
                     /locus_tag="OPY25_000116"
     ncRNA           18729..18847
                     /ncRNA_class="other"
                     /locus_tag="OPY25_000116"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(18838..19845)
                     /locus_tag="OPY25_000117"
     CDS             complement(18838..19845)
                     /locus_tag="OPY25_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCS0925849.1"
                     /translation="MAVQNKKRAKLIDVARHAGVSPGTVSNALHNTRFVEPQTRRRIE
                     EAIVALNYTPNIRARQLRTGKTNTIALLSSVPLAIASGASRLGFMMEVALTSAMMALE
                     KQHALILVPPGVNPLDAVSFDAAILIEPAENDPQLQALAQAGIPCVTIGRTPGTDTPV
                     PWVELHSAATAQLLLTHLEASGASKCALFVGNTRRTSVLESEAAYQRWCAGRQDPVVY
                     SLNESEGENAGYQAAQQLLQAHPDVDGVLVLIDTFASGAVRAFQEQDIAIPEQIRVVT
                     RYDGIRARESLPPLTAVNMHLDEVARQAITLLFAVLSGEKVSYSDGIMPELVVRASTC
                     R"
     gene            19995..21119
                     /locus_tag="OPY25_000118"
     CDS             19995..21119
                     /locus_tag="OPY25_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCS0925850.1"
                     /translation="MAHLTQDSTFTLGRRPAGLIYADKAKSFGGYTLFAPQTAEGRVY
                     LVDEQGEVAHQWQLPVRAGRDAVLLPNGNLGYNGSHRTSANLYPAWDLWHGGDFYEVT
                     PDNEIVWHYEDIYHHHDAQWLANGNLLYTAASPLPADIAARVTGGDPRRDAPDGVIQS
                     DVVKEVNRDGEVVWEWRAWEHLNPEDFPIHDIFDRRHWPMINGLSVTRDGLVLMSLRT
                     TSGVIAVDKESGKVIWHAGPEVVAQQHTPVEMENGSILVFDNGNLRPGVTSPHSTVLE
                     FDPQIKAITWQYRDIFPPAFFSPYMGSAQRLANGNTFICESAFGRLFEVTPEGETVWE
                     YIIPFFNEYPEHLSKGIIPGKQNSAFRAHRYAADAISWLK"
     gene            21177..22501
                     /locus_tag="OPY25_000119"
                     /pseudo
     CDS             21177..22501
                     /locus_tag="OPY25_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462533.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease"
     gene            23057..24664
                     /locus_tag="OPY25_000120"
     CDS             23057..24664
                     /locus_tag="OPY25_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCS0925851.1"
                     /translation="MSISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPIYNRLVEFKTGTTEVIPGLAEKWDISEDGKTYTFHLRKGVKWQ
                     SSKDFKPTRELNADDVVFSFDRQKNEQNPYHKVSGGSYEYFEGMGLPDLISEVKKVDD
                     HTVQFVLTRPEAPFLADLAMDFASILSKEYADNMLKAGTPEKVDLNPVGTGPFQLVQY
                     QKDSRILYKAFDGYWGTKPKIDRLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KEDKNINLMEQAGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKEAIIKAVYQGAGVAA
                     KNLIPPTMWGYNDDIKDYGYDPEKAKALLKEAGLEKGFTIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKIGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     DAAQQGSNYSKWCYKPFEDLIQPARATDDHNKRIELYKQAQVVMHDQAPALIIAHSTV
                     YEPVRKEVKGYVVDPLGKHHFENVSVE"
     gene            24821..25840
                     /gene="dppB"
                     /locus_tag="OPY25_000121"
     CDS             24821..25840
                     /gene="dppB"
                     /locus_tag="OPY25_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HCS0925852.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKATLEL
                     GVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDTNPLTGFMLIDTAIWGEEGNFIDALAHMILPAMVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            25850..26752
                     /gene="dppC"
                     /locus_tag="OPY25_000122"
     CDS             25850..26752
                     /gene="dppC"
                     /locus_tag="OPY25_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HCS0925853.1"
                     /translation="MSQVTENNVNAAPAPMTPLREFWHYFKRNKGAVVGLAYVLIVIL
                     IAVFANFIAPYNPAEQFRDALLAPPVWQEGGSWAHILGTDDVGRDALSRLMYGARLSL
                     LVGCLVVVLSLVMGIILGLVAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            26763..27746
                     /gene="dppD"
                     /locus_tag="OPY25_000123"
     CDS             26763..27746
                     /gene="dppD"
                     /locus_tag="OPY25_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HCS0925854.1"
                     /translation="MALLNVDQLSVHFGDEGTPFKAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAENLLFNGQDLKRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGAAQDIFRAPRHPYTQALLRALPEFAQDKARLASLPGVVPG
                     KYDRPTGCLLNPRCPHATDRCRAEEPALNQLDDGRQSKCHYPLDDAGRPTL"
     gene            27743..28756
                     /gene="dppF"
                     /locus_tag="OPY25_000124"
     CDS             27743..28756
                     /gene="dppF"
                     /locus_tag="OPY25_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HCS0925855.1"
                     /translation="MSTHEATLQQPLLRAIDLKKHYPVKKGIFSPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMVETPTGGELYYQGQDLLKHDPHAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALAMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQDMGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLTGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKEYDGQLVACFAVDQDENPQK
                     PLS"
     gene            complement(29066..30364)
                     /locus_tag="OPY25_000125"
     CDS             complement(29066..30364)
                     /locus_tag="OPY25_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HCS0925856.1"
                     /translation="MQDDTLPLNNSNATTTPLSTRLPFTKYDFGWVLLCIGMAIGAGT
                     VLMPVQIGLKGIWVFITAFIIAYPATYIVQDIYLKTLSESETCDDYTDIISHYLGKNW
                     GVFLGVIYFLMIIHGVFIYSLSVVFDSASYIKTFGLTEADLSQSIIYKVAIFAVLVAI
                     ASGGEKLLFKISGPMVVVKVGIILIFGLAMIPHWNLDNISAFPAASVFFRDVLLTIPF
                     CFFSAVFIQVLNPMNIAYRKREPDRVLATRMAIRTHRISYITLIAIILFFSFSFTFSI
                     SHEEAVSAFEQNISALALAAQVIPGQIIHITSTILNIFAVLTAFFGIYLGFHEALKGI
                     VLNVLSRIMDVKNINPLLLTSGICVFIVVTLVIWVSFRVSVLVFFQLGSPLYGIVACI
                     IPFFLIYKVAQLEKLRGLKTWLILLYGILLCLSPLLKLIE"
     gene            complement(30482..30879)
                     /locus_tag="OPY25_000126"
                     /pseudo
     CDS             complement(30482..30879)
                     /locus_tag="OPY25_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133841.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
     gene            31007..31114
                     /locus_tag="OPY25_000127"
     CDS             31007..31114
                     /locus_tag="OPY25_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HCS0925857.1"
                     /translation="MTLTQLGVAFWHDLAAPIIAGIIASVIVNWLRDRK"
     gene            complement(31196..32875)
                     /gene="bcsG"
                     /locus_tag="OPY25_000128"
     CDS             complement(31196..32875)
                     /gene="bcsG"
                     /locus_tag="OPY25_000128"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HCS0925858.1"
                     /translation="MTQHTQTPSMPSPLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFMAFLLMPIPKYRLHRLRHWIAIPVGFALFWHDTWLPGPQSIMSQGTQVAEFS
                     SGYLLDLIARFINWQMIGAIFVLLVAWLFLSQWIRVTVFVVAIMVWLNVLTLTGPVFT
                     LWPAGQPTDTVTTTGGNAAATVATAGDKPVIGDMPAQTAPPTTANLNAWLNTFYAAEE
                     KRKTTFPAQLPPDAQPFDLLVINICSLSWSDVEAAGLMSHPLWSHFDILFKHFNSGTS
                     YSGPAAIRLLRASCGQPSHTRLYQPANNECYLFDNLAKLGFTQHLMMDHNGEFGGFLK
                     EVRENGGMQSELMNQSGLPTALLSFDGSPVYDDLAVLNRWLTGEEREANSRSATFFNL
                     LPLHDGNHFPGVSKTADYKIRAQKLFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQISGLRDIPSPSITNVPAGVKFFGMKAPHEGAPIDINQPSSYLAISELVVRAVDGK
                     LFTEDSVNWNKLTSNLPQTAPVSENANAVVIQYQGKPYVRLNGGDWVPYPQ"
     gene            complement(32872..33063)
                     /gene="bcsF"
                     /locus_tag="OPY25_000129"
     CDS             complement(32872..33063)
                     /gene="bcsF"
                     /locus_tag="OPY25_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HCS0925859.1"
                     /translation="MMTISDIVQIILFCALIFFPLGYLARHSLRRISDTTRLLFAKPR
                     YVKPAGTLRRATKVKADKK"
     gene            complement(33060..34631)
                     /gene="bcsE"
                     /locus_tag="OPY25_000130"
     CDS             complement(33060..34631)
                     /gene="bcsE"
                     /locus_tag="OPY25_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HCS0925860.1"
                     /translation="MRDTVDPVFSLGISSLWDELRHMPTGGVWWVNADRQQDAISLVN
                     QTIASQTENANVAVIGMEGDPGKVIKLDESHGPEKIRLFTMPDSEKGLYSLPHDLLCS
                     VNPTHYFFILICANNTWRNITSESLHKWLEKMNKWTRFHHCSLLVITPCNNSDKQSSL
                     LMGEYRSLFGLASLRFQGDQHLFDIAFWCNEKGVSARQQLLLCQQDERWTLSHQEETA
                     IQPRSDEKRILSHVAVLEGAPPLSEHWTLFDNNEALFNDARTAQAATIIFSLTQNNQI
                     EPLARRIHTLRRQRGSALKIVVRENIASLRATDERLLLGCGANMIIPWNAPLSRCLTL
                     IESVQGQQFSRYVPEDITTLLSMTQPLKLRGFQPWDTFCDAIHTMMSNTLLPADGKGV
                     LVALRPVPGIRVEQALTLCRPSRTGDIMTIGGNRLVLFLSFCRVNDLDTALNHIFPLP
                     TGDIFSNRMVWFEDKQISAELVQMRLLSPELWGTPLPLAKRADPVINAEHDGRIWRRI
                     PEPLRLLDDTAERAS"
     gene            34876..35079
                     /locus_tag="OPY25_000131"
     CDS             34876..35079
                     /locus_tag="OPY25_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HCS0925861.1"
                     /translation="MYNNEPGAQSDPTLGYTFQNDFLALSQAFSLPEIDYTDISQREQ
                     LAAAIKRWPLLAEFAQPHSLRKP"
     gene            35080..35832
                     /gene="bcsQ"
                     /locus_tag="OPY25_000132"
     CDS             35080..35832
                     /gene="bcsQ"
                     /locus_tag="OPY25_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HCS0925862.1"
                     /translation="MAILGLQGVRGGVGTTSLTAALAWALQILGENVLVIDASPDNLL
                     RMSFNVDFVHQGGWARSLLDGQDWRDAGLRYTSQLDLLPFGQLTSQEWENPQAWQETL
                     GEIGSAIQALKASGRYSWILLDLPYGESPLTRQLVSLCDHTLAIAQVDANCHIRLHQQ
                     ALPAGAHILINDLRIGSQLQDDLYQVWLQSQRRLLPIVIHRDEAMAECMASKQPLGEY
                     RSDSLAAEEVLTLANWCLLHDAGDKTSAGSLR"
     gene            35829..38453
                     /gene="bcsA"
                     /locus_tag="OPY25_000133"
     CDS             35829..38453
                     /gene="bcsA"
                     /locus_tag="OPY25_000133"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HCS0925863.1"
                     /translation="MSALSRWLLIPPVSARLSERYQGYRRHGASPFSAALGCLWTILA
                     WIVFPLEHPRWQRIRDGHKALYPHINAARPRPLDPARYLIQTLWLVMISSTKERHEPR
                     WRSFARLKDVRGRYHQWMDTLPERVRQKTTHLEKEKELGHLSNGARRFILGVIVTFSL
                     ILALICITQPFNPLSQFIFLLLLWGVALLVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKEMSQWPTVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGRESFRQFARHVGVHYIARA
                     THEHAKAGNINNALKHAKGEFVAIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQSAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLFGKGLKLAQRLCYLNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     IPHMVHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEKYVDWVISRPYIFLVLLNLLGVAAGVWRYYYGPENETLTVIVSLVWVFYNLVIL
                     GGAVAVSVESKQVRRAHRVEIAMPGAIAREDGHLFSCTVHDFSDGGLGIKINGQAQVL
                     EGQKVNLLLKRGQQEYVFPTQVVRVTGNEVGLQLMPLTTKQHIDFVQCTFARADTWAL
                     WQDSFPEDKPLESLLDILKLGFRGYRHLAEFAPPSVKVIFRSLTALIAWIVSFIPRRP
                     ERQAAIQPSDRVMAQAQQ"
     gene            38464..40764
                     /gene="bcsB"
                     /locus_tag="OPY25_000134"
     CDS             38464..40764
                     /gene="bcsB"
                     /locus_tag="OPY25_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HCS0925864.1"
                     /translation="MKRKLSWMCAAVIGLSAFPAFMTAAAPAMPPLINAEPTEPAQSP
                     VTEAPVVAQTAPSREVKLTFAQIAPPPGSMALRGVNPNGGIEFGMRSDEVASKAVLNL
                     EYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQVPINPLFITDFNRGRLE
                     FVGHYRDVCENPASSTLWLDIGRNSALDLTYNMLAVNNDLSHFPVPFFDPRDNRPVTL
                     PIVFADMPDLAQQQAASIVASWFGSRAGWRGQRFPVLYNHLPDRNAIVFATNDRRPDF
                     LRDHPAVNAPVIEMMNHPDNPYVKLLVVFGRDDKDLLQAAKGIAQGNILFRGSSVVVN
                     DVKPLLARKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAPINVSLNLPPDLYLL
                     RSNGIDMDLNYRYTSPPTKDSSRLDISLNNQFLQAFSLNSTQETNRLLLRLPVLQGLL
                     DGKTDVSIPALKLGAMNQLRFDFRYMNPMPGGSVDNCITFQPVPNHVVIGDDSTIDFS
                     KYYHFIAMPDLRAFANAGFPFSRMADLSDTLAVMPKTPTEAQMETLLNTVGAIGGQTG
                     FPAINLTITDDSAQIADKDADLLIIGAIPGKLKDDKRIDLLVQATQSWVKTPMRQTAF
                     PSIMPDEADRAADAQSTVTASGPMAAVVGFQSPFNDQRSVIALLADSPRGYQLLNDAV
                     NDSGKRAAMFGSVAVIRESGVHSLRVGDIYYVGHLPWFERLWYALANHPVLLAVLAAL
                     SVVLLAWVLWRLLRILSRRRLDPDHE"
     gene            40768..41877
                     /gene="bcsZ"
                     /locus_tag="OPY25_000135"
     CDS             40768..41877
                     /gene="bcsZ"
                     /locus_tag="OPY25_000135"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
                     /protein_id="HCS0925865.1"
                     /translation="MMTMLRGWITMIVMLTAINAQAACSWPAWEQFKKDYISQQGRVI
                     DPGDARKITTSEGQSYAMFFALAANDRPAFAQLFNWTQNNLAQGSLREHLPAWLWGQK
                     DPDTWSVLDSNSASDGDIWMAWSLLEAGRLWKETRYTEVGTALLKRIAREEVVNVPGL
                     GSMLLPGKIGFAEANSWRFNPSYLPPQLAQYFSRFGAPWSTLRETNLRLLLETSPKGF
                     SPDWVRYESKQGWQLKAEKTLISSYDAIRVYLWTGMMHDGDPQKARLLARFKPMATLT
                     MKNGVPPEKVDVVSGNAQGTGPVGFSAALLPFLQNRGAQAVQRQRVADHFPGSDAYYN
                     YVLTLFGQGWDQHRFRFTVKGELLPDWGQECVSSR"
     gene            41859..45402
                     /gene="bcsC"
                     /locus_tag="OPY25_000136"
                     /pseudo
     CDS             41859..45402
                     /gene="bcsC"
                     /locus_tag="OPY25_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462517.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
     gene            45576..47582
                     /gene="hmsP"
                     /locus_tag="OPY25_000137"
     CDS             45576..47582
                     /gene="hmsP"
                     /locus_tag="OPY25_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HCS0925866.1"
                     /translation="MRVSRSLTIKQMAMVAAVVMVFVFVFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKADLPGAETILESIKPAGVVSRADVVLPNQFQALRKRFIP
                     ERPVPVMVTRLFELPVQISLPVYSLERPANPQPLAYLVLQADSYRMYKFVMSALSTLV
                     TIYLLLSLILTVAIAWCVNRLIVHPLRKIARELNDIPQQELIGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLMQRQREEQTDNAMRFPVSELPNKAFLMALLEQVITRQQTTALIIVT
                     CETLRDTAGVLQETQREILLLTLVEKLKSVLAPRMVLTQVSGYDFAIIAHGVKEPWHA
                     ITLGQQILTIINERLPIQGIQLRPSCSIGIAMYYGDLTAEALYGRAVSAAFTARRKGK
                     NQIQFFDPAQMEAAQQRLTEESDILTALDNHQFAIWLQPQVEMRSGNVLSAEALLRMQ
                     QPDGSWELPEGLIERIESCGLMVTVGHWVLEESCRQLAAWQERGVTLPLSVNLSALQL
                     MHPGMVSDLLELLNRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRIALDDF
                     GMGYAGLRQLQHMKSLPVDILKIDKMFVDGLPDDHSMVTAIILMARSLNLQLIAEGVE
                     DEAQRAWLEQAGVNVAQGFLFARPVPADIFEERYLSHENPDYKS"
     gene            47740..49026
                     /gene="dctA"
                     /locus_tag="OPY25_000138"
     CDS             47740..49026
                     /gene="dctA"
                     /locus_tag="OPY25_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HCS0925867.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHYYPELGAQMKPLGDAFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALINGLIIVNVVQPG
                     AGMNVDPATLDAQAVAVYAAQAKEQGIIAFLMDVIPGSVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLVQ
                     LGQLIICFYITCILFVVVVLGTIARVTGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLV
                     VLLLSSKGAAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATVVVAKWVKELDHQKLDDVLNNRAPDGKTHEISS"
     gene            49246..50733
                     /locus_tag="OPY25_000139"
     CDS             49246..50733
                     /locus_tag="OPY25_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCS0925868.1"
                     /translation="MQGTKIRLLAGSLLMLASAGYVQADALQPDPAWQQGTLANGLQW
                     QVLATPQRPSDRIEVRLQVNTGSLTESTQQSGFSHAIPRIALTQSGGLDAAQARSLWQ
                     QGFDPKRPMPPVIVSYDSTLYSLSLPNNRNDLLKEALTYLANVSGKLTITPETVNHAL
                     SSEDMVATWPADTKEGWWRYRLKGSALLGHDPAEPLKQPVDAAKIQAFYEKWYTPDAM
                     TLIVVGNIDARSVAEQINKTFGTLKGKRETPAPVPTLSPLRAESVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWQADLAREALFWHIQQELTKNNAKDIGLGFDCRVLFLRA
                     QCAINIESPNDKLNTNLSLVANELAKVRDKGLSEEEFTALVAQKNLELQKLFATYART
                     DTDILTGQRMRSLQNQVVDIAPEQYQKLRQNFLNSLTVDMLNQNLRQQLSQEMALILL
                     QPQGEPEFNMKALKATWDEIMVPATAAAVEADEAHPEVTETPAAQ"
     gene            complement(50787..51716)
                     /locus_tag="OPY25_000140"
     CDS             complement(50787..51716)
                     /locus_tag="OPY25_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCS0925869.1"
                     /translation="MSKKIAVIGECMIELSQKGADVQRGFGGDTLNTSVYIARQVDSA
                     ALAVHYVTALGTDSFSQQMLEAWQHENVDTSLTQRMENRLPGLYYIETDDTGERTFYY
                     WRNEAAAKFWLESEQSAAICETLATFDYLYLSGISLAILSPTSRDKLLSLLRECRANG
                     GKVIFDNNYRPRLWTSREETQQVYQKMLECTDIAFLTLDDEDALWGKQPVEEVIARTH
                     AAGVQEVVVKRGADSCLVSIQGEALIDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSATDAAKRGHLTASTVIQYRGAIIPHDAMPQ"
     gene            51945..52712
                     /gene="pdeH"
                     /locus_tag="OPY25_000141"
     CDS             51945..52712
                     /gene="pdeH"
                     /locus_tag="OPY25_000141"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HCS0925870.1"
                     /translation="MIKQVIQQLRVPDAGIENLQERRYWLQCERAYTYQPIYQTDGRL
                     MTVELLTAVTHPDNPSRRIAPDRYFAELAVRHRIDVVKEQLHQLEQKADFFTRHRLLA
                     SVNVDGPTLIAMRQQPDILAAMERLPWLRFELVEHIRLPKDSSFASMCEFVPLWLDDF
                     GTGMANFSALSEVRYDYIKVARELFVMLRQSPEGRNLFILLLQLMNRYCRGVIVEGVE
                     TLEEWRDVQRSPAFAAQGYFLSRPVPLISLEEVILTL"
     gene            52822..54882
                     /locus_tag="OPY25_000142"
     CDS             52822..54882
                     /locus_tag="OPY25_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HCS0925871.1"
                     /translation="MTKAGKITAAITGTFLLLIAIVILLIATFDWNRLKPTINQKVST
                     ELNRPFAIRGDLGVVWERQKQESGWRSWVPWPHVHAEDVILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLVKPDARLIRLSEKTNNWTFNLAQDKNTDPNAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADITILVDPLGKPLPFSEVTGTKGKADKSTVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRSESTPFPVQADFRSGNTRVAFSGVVNEPMKMGG
                     VDLRLKFSGDSLGDLYDLTGVLLPDTPPFETDGRLVAKIDAEKSSVFNYRGFNGRIGD
                     SDIHGTFTYTTGKPSPKLEGDVESRQLRLADLGPLIGVDSGKDAEQSKRSEQRKGEKN
                     VQPADKVLPYDRFETDKWDVMDADVRFKGRRIEHGGSLPISDLSTHIILKNADLRLQP
                     LKFGLAGGSIVSNIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGELNGDAD
                     IRGTGNSVAALLGNSNGNLKLLMNDGLISRNLMEIVGLNVGNYIIGQIFGDDEVRVNC
                     AAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKPGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILT
                     QMKQ"
     gene            complement(54922..56244)
                     /locus_tag="OPY25_000143"
     CDS             complement(54922..56244)
                     /locus_tag="OPY25_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HCS0925872.1"
                     /translation="MQATATTLDHEQEHVPVNSRNKVVIASLIGTAIEFFDFYIYATA
                     AVIVFPLIFFPQGDPTAATLQSLATFAIAFVARPIGSALFGHFGDRVGRKVTLVASLL
                     TMGISTVIIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFPLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHETPVFAKVAAAKKQVKIPLGTLLTKHVHVTILGTFIMLATYTLFYIMTVYSMTYST
                     AAAPVGLGLPRNEILWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFTPLLGSGNPALVFVFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVSSI
                     LGASVAPYIAAWLQSHYGLAAVGVYLASMAALTLIALLLTHETRHQAL"
     gene            complement(56595..57623)
                     /gene="yhjD"
                     /locus_tag="OPY25_000144"
     CDS             complement(56595..57623)
                     /gene="yhjD"
                     /locus_tag="OPY25_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HCS0925873.1"
                     /translation="MTQENDVKRPIQELEHDPIQKIETQPHDAPEKNEKANQALHSVT
                     TLMQKIQRQPMVAHLIRATERFNDRLGNQFGAAITYFSFLSMIPIMMVSFAAAGFILA
                     SHPNLLEDIFSKILMNVSDPTLASTLKNTINTAVQQRTTVGLVGLGIALYSGVNWMGN
                     LREAIRAQSRDVWERKPQDQEKIWLKYLRDFISLIGLLIALIITLSITSIAGSAQQMI
                     ISALYLDSIEWLKPAWHLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFIAAI
                     GFEVIKIIMTYTLPSLVKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDP
                     RMPGKTQR"
     gene            complement(57696..58595)
                     /locus_tag="OPY25_000145"
     CDS             complement(57696..58595)
                     /locus_tag="OPY25_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0925874.1"
                     /translation="MDKIYAMKLFVRVAERESFSRAAEDIGLPKGSVSRQIQALEHQL
                     GIRLLHRTTRRVQLTQDGMVYYERAKDLLSNLDELEGLFQPDPASISGKIRVDIPPGL
                     ANSLIMPRLLTFLHQYPGIALELCSSDRQVDLLREDFDCVVRTEPLHAPGILTRPLGK
                     LRRVNCASPQYLARFGYPENLDDLASHAMVHYSLTPGVSSPGFAFETPHGMQWVKTGG
                     MLTVNSTETWHTACLAGLGIIQTPRIAVREALRAGALIEILPQYRAAPLPVTLHYPHR
                     RNLSRRVHLFMVWLTETIKEAAE"
     gene            59226..59828
                     /locus_tag="OPY25_000146"
     CDS             59226..59828
                     /locus_tag="OPY25_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCS0925875.1"
                     /translation="MQVIMFDRQSIFIHGMKISLQQHIPGISIQSVGQAEELWQKIES
                     APDALVMLDSGLDAEFCREVLQRTAQQFPEVKIIITAMDGSQKWLHEVMQFNVQVVVP
                     RDSDAETFVLALNTVARGMMFLPGDWLNSTELESHDIKALSARQREILQMLAAGESNK
                     QIGRALNISTGTVKAHLESLYRRLDVKNRTQAAMMLNESN"
     gene            complement(59834..60190)
                     /locus_tag="OPY25_000147"
     CDS             complement(59834..60190)
                     /locus_tag="OPY25_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HCS0925876.1"
                     /translation="MPHISSRFSSACIAFIKQWQGLSLEKYRDRQGNWVIGYGHMLTP
                     DETLTFITPDQAEAFLLDDLNSCDMLLQNCLPELNDRFQRETLIALMFSIGHQRFLSL
                     INTDDISQPEISGLRI"
     gene            60471..62060
                     /locus_tag="OPY25_000148"
     CDS             60471..62060
                     /locus_tag="OPY25_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0925877.1"
                     /translation="MTNSASQATRAPFEHSLGIIRQASIEILLLLGIHTTEGKEPRWF
                     MEQLEQARLNLGGWGAVAKKLRINDAQLSQFMLQLRHLQQHVPQYDSGQEVSENQLLA
                     ALRFVTSLEHLRQQQPLLTYQTELEDPDQEAHLEAQRQLRAIELTLKALIARAWPDRA
                     SLNHYLKQHFGPDRLRQWLKQGEDQHALEGMLFSELALMVVDKKLFARHYVRIFNDAS
                     ALTLFAESRTTLRMFLDDCRLARNEVIARQPLTSAQLMLLNVQYQQIVRPIQRAYAEK
                     RTRVNPASFLLADERELRQFWETARLKDRQAGGDKHEISESIEPPRKRPPRTPEEREQ
                     LISGALWGGVGVMTLAILAGAFWLFSSSSPSSDNGQAPAMAQDEPPREAPSARETLNH
                     MGITWDAFTMRAAIERNDTRVTALFLQGGMNWQLAWTEQAFAAGHTEVLQLLLRYPAL
                     MDEVKPCRRFITTLSHDMSSGAPLTAMHKTYLQTFCTVPAVVTRQQYDTEQAQLRAQA
                     RPSADNKKWLKIQSAIYDAIH"
     gene            complement(62073..63722)
                     /locus_tag="OPY25_000149"
     CDS             complement(62073..63722)
                     /locus_tag="OPY25_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HCS0925878.1"
                     /translation="MLNQKLNPTPSEDLTIDVDLFYETDPCELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSTKLFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRRFVENHFWLPETLSSEYVSNPENSLKEHIDQLWPILTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLALNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     AGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGERDTEALFRQKASDRRAAVNHY
                     LWDDENGCYRDYDWRREEMALFSAASIVPLYVGMANHEQADRLANVVRSRLLTPGGIM
                     ATEYETGEQWDKPNGWAPLQWMAIQGFKRYGDDMLGDEIAHNWLKTVNHFYQEHHKLI
                     EKYHISGGTPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            64047..64766
                     /locus_tag="OPY25_000150"
     CDS             64047..64766
                     /locus_tag="OPY25_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0925879.1"
                     /translation="MIEQPDSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSV
                     RWQVSRVTVRKALDALTRENLLTRVSGKGTFVSGEKFQRSMTGIMSFSELCQSQGRRP
                     GSRTIKSVFESVDDETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPPRFAFLLD
                     EDLNNHSLYECLREKYHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDN
                     KGELSCVSQQLIVGDKIRFTV"
     gene            64945..65796
                     /locus_tag="OPY25_000151"
     CDS             64945..65796
                     /locus_tag="OPY25_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCS0925880.1"
                     /translation="MGMKETVSNIVTSQAEKGGVKHVYYVACGGSYAAFYPAKAFLEK
                     EAKALTVGLYNSGEFINNPPVALGENAVVVVASHKGNTPETIKAAEIARQHGAPVIGL
                     TWIMDSPLVAHCDYVETYTFGDGKDIAGEKTMKGLLSAVELLQQTEGYAHYDDFQDGV
                     SKINRIVWRACEQVAERAQAFAQEYKDDKVIYTVASGAGYGAAYLQSICIFMEMQWIH
                     SACIHSGEFFHGPFEITDANTPFFFQFSEGNTRAVDERALNFLKKYGQRYYPETFTEG
                     ECVIGAG"
     gene            65729..66059
                     /locus_tag="OPY25_000152"
                     /pseudo
     CDS             65729..66059
                     /locus_tag="OPY25_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462499.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
     gene            complement(66106..67458)
                     /gene="gorA"
                     /locus_tag="OPY25_000153"
     CDS             complement(66106..67458)
                     /gene="gorA"
                     /locus_tag="OPY25_000153"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCS0925881.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHLYGPDYGFDTTINQFDWSKLIASRTAYIDRIHTSYDNV
                     LGKNNVDVIKGFARFVDAKTIEVNGETITADHILIATGGRPSHPSIPGVEYGIDSDGF
                     FALSALPERVAVVGAGYIAVELAGVINALGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTHAVPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPSTDNINLAAAG
                     VKTNEKGYIIVDKWQNTNVEGIYAVGDNTGAIELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLSEPQAREQYGDEQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGPEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTASEEFVTMR
                     "
     gene            complement(67563..68405)
                     /locus_tag="OPY25_000154"
     CDS             complement(67563..68405)
                     /locus_tag="OPY25_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase
                     RlmJ"
                     /protein_id="HCS0925882.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKEKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEPYISVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDFPLLRAEFQKDNRARVERADGYQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGISEGYKRFATGTYALWYPVVLRQQIKRMIHELEATGIRK
                     ILQIELAIRPDSDQRGMTASGMIVVNPPWKLEQQMNNVLPWLHSRLAPNGHGHTSVSW
                     IVPE"
     gene            complement(68526..68969)
                     /locus_tag="OPY25_000155"
     CDS             complement(68526..68969)
                     /locus_tag="OPY25_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000209569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0925883.1"
                     /translation="MTTLLQVIVLIFIVFFIFPGRKIFRRSKHLQDGRKLISSSSLML
                     RKFGSSRGYNADYYFDMQYLYEVADGITTAIPLTSIIEAKPGTTRVSGRSVWSVDWIT
                     AEGQRKQTRFLHNYTLFNRNFATFLKTVKQANPDACITSLTLFTL"
     gene            69247..69900
                     /locus_tag="OPY25_000156"
     CDS             69247..69900
                     /locus_tag="OPY25_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0925884.1"
                     /translation="MFHYGKCVVRTLFLLLVCCSLSGCLSFGLILATDKDGNRHQSTW
                     KSDTVTALSLGKDSNGKTGWVFVGEHFDYLLTQGGDNVVALLKDATIRRDKMRVKDGV
                     KFLIDTDKKEFTGEVNVTYAWVDEKDKLAAVGYGFICADGAVNCTLSVMDLKGTIHQK
                     NKEQSVTQQLSFYHPFTVEFYQYQRSMSGAKFGRVLLPVTLALDIVTMPLQLLIFSR"
     gene            70063..72105
                     /gene="prlC"
                     /locus_tag="OPY25_000157"
     CDS             70063..72105
                     /gene="prlC"
                     /locus_tag="OPY25_000157"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HCS0925885.1"
                     /translation="MTNPLLTSFSLPPFSAIKPEHVVPAVTKALADCRAAVEGVVAHG
                     APYSWENLCQPLAEADDVLGRIFSPISHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYNAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLITDEAELAGMPESALAAAKALAEAKEQEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSPVMEEILALRHELAQLLGFE
                     NYAHESLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVEELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERTDVDVWHPEVR
                     FFELYDENNELRGSFYLDLYAREHKRGGAWMDDCVGQMRKADGTLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFN
                     PQQGAKILDTLFEIKKQVAVVPSPTWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     YSRFEEEGIFNRETGQSFLDNILTRGGSEEPMELFKRFRGREPQLDAMLEHYGIKG"
     gene            72112..72870
                     /gene="rsmJ"
                     /locus_tag="OPY25_000158"
     CDS             72112..72870
                     /gene="rsmJ"
                     /locus_tag="OPY25_000158"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HCS0925886.1"
                     /translation="MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVK
                     RPDYAPPLADVATPNAIVTKEHRFDIYAGTPLTE"
     gene            complement(72962..74431)
                     /gene="dtpB"
                     /locus_tag="OPY25_000159"
     CDS             complement(72962..74431)
                     /gene="dtpB"
                     /locus_tag="OPY25_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HCS0925887.1"
                     /translation="MNTTAPTGLLQQPRPFFMIFFVELWERFSYYGVQGILAVFFVKQ
                     LGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGTKRTLVLGAIVLAIGYFMTGMSL
                     LNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
                     SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVL
                     LGTVVMIFLCAWLMHNVKIANLVLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMI
                     EAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPFWVVVASPVLAAIYT
                     RLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGE
                     LLISALGLAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTL
                     PIYTGVFSKIGLVTLAVTVVMAIMVPWLNRMINTQGTEQ"
     gene            complement(74756..75190)
                     /gene="uspA"
                     /locus_tag="OPY25_000160"
     CDS             complement(74756..75190)
                     /gene="uspA"
                     /locus_tag="OPY25_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HCS0925888.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKISLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISKETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            75578..75913
                     /gene="uspB"
                     /locus_tag="OPY25_000161"
     CDS             75578..75913
                     /gene="uspB"
                     /locus_tag="OPY25_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HCS0925889.1"
                     /translation="MISTVSLFWALCVVCIVNMARYFSSLRALLVVLRGCDPLLYQYV
                     DGGGFFTTHGQPNKQVRLVWYIYAQRYRDHHDEEFIRRCERVRRQFLLTSALCGLVVV
                     SLIALMIWH"
     gene            complement(76053..77549)
                     /gene="pitA"
                     /locus_tag="OPY25_000162"
     CDS             complement(76053..77549)
                     /gene="pitA"
                     /locus_tag="OPY25_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HCS0925890.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSAHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNAMMTGTSVVDALNIPKVINIFGSLI
                     ISPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNASSYEITRTRDAINNVETYFEQ
                     RPDLLKAVTGVDQLIPSPEPGATEPTEFHCHPANTINALNRAKGMLANVESYDKLSVE
                     QRSQLRRIMLCISDTTDKVVKLPGVSSDDQRLLKKLKTDMLSTIEYAPVWIIMAVALA
                     LGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVLS
                     SSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIILSGVLYWLSLKII"
     gene            77780..78982
                     /locus_tag="OPY25_000163"
     CDS             77780..78982
                     /locus_tag="OPY25_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCS0925891.1"
                     /translation="MERFDAVIIGAGAAGMFCAAQAGQAGSRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPAAYLSQNPHFCKSALARYTQWDFIDLVGRYGIAWHEKTLGQLF
                     CDDSAQRIVDMLVAECDKGGVTMRLRSEVLSVERDESGFVLALNGETVTTQKLVIASG
                     GLSMPGLGASPFGYKIAEQFGLKVLPTRAGLVPFTLHKPLLEQLQTLSGVSVPCVITA
                     RNGTVFRENLLFTHRGLSGPAVLQISSYWQPGELVSINLLPDLSLEDVLNEQRNAHPN
                     QSLKNTLAMHLPKRLVECLQQLGLIPDVSLRQLNVRDQQTLVDTLTAWQVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARRVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIALKIN"
     gene            complement(79484..80635)
                     /locus_tag="OPY25_000164"
     CDS             complement(79484..80635)
                     /locus_tag="OPY25_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0925892.1"
                     /translation="MYLREVFYYPWNEYFSLTNTQSGMLMSWLGFVGIISGAVSGIIV
                     DRFKNPKSILTIAYLTMAALAIWQSFRPSYQAMFIIVGFMSLVGNGLFLVSMTKIARL
                     LASDNEQGRYFGFLESGRGIAGTVLTLCAVAIVGLHGSSAVSIGFILRFDAAIYIILG
                     FTSYYLFPKGVSAIENAAPKKMSDLISLLKSVKLWLAAFIISCVIFVYQGGAYLVPYL
                     SDAYGMTPDQTAVIGMIRAYFLAFIISPFAGLLADKIGSSLKVMASFFILGALITASF
                     IFIPHDSRFLILLITLVLLLGALTFGMRGIMYAQVNEIRIPKVFTGTAMGILICIGFS
                     PEAYVHLIFGYLLDTYKEFAYTLMFATIAVVLFAGALCSGLLYRINKKV"
     gene            complement(80779..81426)
                     /locus_tag="OPY25_000165"
     CDS             complement(80779..81426)
                     /locus_tag="OPY25_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCS0925893.1"
                     /translation="MKNTCLEPYEFLIDFLADYFGENTEVVLHNLSDLESSIHKIRNG
                     HISGRSVGDPITDLVVRAMKNNDSEVHYQCNYLSKTRDGRRLKCATFFIRNKQGEIVG
                     ALCLNTVVEDLIALNDKLSHFLSIFVGQTDNNNGTQLDEHIGLTIPEMVDLKINNVIN
                     IENINPESLNAENKSHIISLLNDEGVFLLKGAVTKVAKKLNISEPTVYKYIQKLK"
     gene            complement(81465..81845)
                     /locus_tag="OPY25_000166"
     CDS             complement(81465..81845)
                     /locus_tag="OPY25_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HCS0925894.1"
                     /translation="MKEIIFTETAPAAIGSYSQGNAMGNLIFTSGQLPINADSGKIET
                     DDIQEQTRQSLLNLLAVVKMAGGDTDTVLKTTCFLSDMADFAAFNDVYASFFKINPPA
                     RSCFAVKTLPMGARVEIEAVAFRQ"
     gene            complement(81855..83021)
                     /locus_tag="OPY25_000167"
     CDS             complement(81855..83021)
                     /locus_tag="OPY25_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCS0925895.1"
                     /translation="MKYDFNEIYQRIASEKWEYDSVINGFPVIPMSVADTDLVSPVEV
                     RQALIEVCNRREFGYPAYHDDFKDVLASWYDRYYDWRPDTADIIETPPLLMTMGAFIR
                     GMTQCNESVVVMTPVYHSFARTIRENHRAVTECDLLRDENNHYTIDFEKLEDTCSRPE
                     NKILIFCNPHNPVGRCWTEEEVRKVAAIAQKTGTILISDEIHADFVYDEKCYTPVMKA
                     AENLNGIIVFLSGGKLFNIGGIFSSYVFTADPVFKKQMAVVLKELHFQPTAFAHEAAY
                     AGYKYYHDYREEVVNHIRKMQIKLVNGLNNMPYPVKANLPEATYLVWADFNDTGWSGD
                     RIQEFLVQDAGLGFNRGDQFGVAGTGFARINCGVPESRIDEALSRLEKAFSKYF"
     gene            complement(83037..84329)
                     /locus_tag="OPY25_000168"
     CDS             complement(83037..84329)
                     /locus_tag="OPY25_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0925896.1"
                     /translation="MKTSNFQKWLMVILLAIGGGTIFKSMYLREVFYYPWNEFMGVNN
                     TDSGLLMSWLGFVGIVSSSIAGVIIDKVNNTRLIISFTFLAVGVTTLWQSTAPGLATQ
                     YVIIGILSFLANGLFLVSMVRATRLIGNASDQGKLFGFLESGRGIAGSAISAVAVAWF
                     AMSATEVEGIGSVLHAYGFLYLALGVLMWFAMPRDNHNSASGEEKAKEKISVHDILAV
                     MKVKEVWFAAFSIFATISFYQGSSYLVPYLSDVYGMTAEHAGIIGMIRAYVLAILIAP
                     VVGLLADKVGSAIKVMNWLFIAGVIGVAMFLVIPQDPAMVWVLIGTLMIVGSINFALR
                     GIMYAQIEEMKVPVRLTGTVMGIMATVGFSPEMFIHALFGYWLDAYKVQGYTYMFIFM
                     GAMFALAVFTSLLLLRNAKTAFKKMDGKPADTFRTAAE"
BASE COUNT        20019 a        21421 c        23017 g        19888 t
ORIGIN      
        1 tgatttttat attattgctg agcaggcgcc tttttcatcg ctatttcttc gcttaatgtg
       61 tctcactcaa ccacaaggag agtgagatgg acgatcacgt tgcacgcagg aaacggatat
      121 tcggcctggg aatgttagtt gtcggtgcag tggtatactt ggtgggattg tggccaggct
      181 gtcatacatt aagcgaaaag ggatattttt ttgcggcaat cgtcatgtgc ggttttccag
      241 tcttaattcg ccaggaacac acggggaatg accgcttgct ttctcgttgt aaatctttgc
      301 tgttgcttgg catcggcatg gtcgcggtcg gcgtatttaa cctggcgctg gcgggcgcgc
      361 tgaaaatact gtgtctggtg gcgctggggg tcagtatata tggaaccgat ctttacgctt
      421 cctacagtga tgatgaatga tggccggagc catcattgtc gtttagctaa cccatttccg
      481 tttatcaata cgctgtaaca gcatggaaag tagcaggctt cctgtcaccg tcgcggcaaa
      541 aacccacacg atgtctaacg gcggccaacg ttttaattcc agaccattag tacgtagcgc
      601 atggataatc agcgcgtgga aaccataaat acccagcgag tggcgggaga taagccccag
      661 tctaggtaac gtccgcgcat tcagcttatt tttaactacc gtgaacagtg agacggcgca
      721 aataaacacc atgggaccgc aatacagata ccaggtatcg gcaaaatttc cgcgccagcg
      781 taattcatgc aatgtgccgc gagaaataac aaataccgcg atgatgaaca gggcagcgca
      841 gataagcgtc agcgatggct tttgcgtctc catcattcca atggcgcggc ccaggatacc
      901 gtagagaatg tagtagaacg tgtcgccgct gatatacaga ttgatgggca accattcaac
      961 gccgccgatt ttttgcggca cagtatttgg gttagcaata ataccaatga tcaccatcag
     1021 catcaggagc attttgccgc tcacgttttt tacctggatt aatggcgata ccaggtagat
     1081 caccgtaatc gcaaagaaaa accacaggtg gtaaaacacg ggtttttgca gcgcattttt
     1141 tagcgaaagc tcgacgttga tcgaagtaaa aagtgaaatg taagccaggg cgacaacgct
     1201 gtaaaagata aggcacaggg caatacgtaa aaaatgccgc ggttgcgcgc agcgctcgcc
     1261 aaaaaaagat agcctgaaat cataaaaaac aggggaacgc taacgcgcga agccgaattc
     1321 aggacattcg caatatccca gtttagcggg ctgacgctgt gggcgttggt gatgtaccac
     1381 gttgtagtat ggatcatcac taccattaaa caggcgatcc ctcgcaggtt atcaatccag
     1441 ttaattttag gctgcatcag ttcctcagct tccgtttcaa tagagttcca gcgcggtggc
     1501 tcactggaaa aatccgactt tctacgctac atcttgtgat ggcgtaagga gattcgcaca
     1561 atgtttctgt tacccacaaa ccttaataat aagactgacc agcaaaccag acggtaataa
     1621 aaatgataat gaagtatttc tgtactgtga tgatagccat cgctctggtg ggatgcacag
     1681 cgacaccgcc accgacgcaa aaagcccagc agagtaaagt gagcccaaca cgcacgctgg
     1741 atatggaagc attgtgtaaa gctcaggcgg cgcagcgtta caacactggc gcacagaaaa
     1801 ttgctgttac cggcttcgaa cagtttcagg ggagctatga gatgcgtggt aataccttcc
     1861 gtaaagagag ttttgtctgc tcttttgatg cagatgggca gtttttacat ctttctatgc
     1921 ggtaaaagcc gcgcctggtg aggtgtgatg ccgcgaaatc cggtaatttt cgctaaacaa
     1981 accggtttca tactgtatat ctcgcatcca gcgggtatac tggctccttc ctttaaatcc
     2041 acacgtatcc agcacgaaat aatatgcaaa agtttgatac caggaccttc cagggcttga
     2101 tcctgacctt acaggattac tgggctcgcc agggctgtac cattgttcaa ccattggaca
     2161 tggaagtcgg cgcgggaact tctcatccaa tgacctgcct gcgcgcgctg gggccagagc
     2221 cgatggcgac tgcctatgtg cagccttctc gtcgtccgac cgatggccgc tacggcgaaa
     2281 acccgaaccg cttacagcac tactatcagt tccaggtagt gattaagccg tctccggaga
     2341 atattcagga gctgtacctc ggttctctga aagagctggg tatggacccg accattcacg
     2401 acatccgttt cgtggaagat aactgggaga acccgacgct gggtgcctgg ggactcggct
     2461 gggaagtgtg gctgaatggc atggaagtga cgcagttcac ctacttccag caggtcggcg
     2521 gcctggagtg caagctggtg accggtgaaa tcacctacgg tctggaacgt ctggcgatgt
     2581 atatccaggg cgtggacagc gtttacgacc tggtctggag cgatggcccg ctgggtaaaa
     2641 ctacctacgg cgacgtgttc catcaaaacg aagttgagca atccacctat aactttgaat
     2701 acgccgatgt ggatttctta ttcacctgct tcgagcagta tgagaaagaa gcccagcagc
     2761 tactagcact ggaaaacccg ctgccgctgc cggcctacga gcgtattctg aaagccgccc
     2821 acagcttcaa cctgctggat gcgcgtaaag ccatctccgt caccgagcgt cagcgttaca
     2881 ttttgcgcat tcgcaccctg acaaaagcag tggcagaagc atactacgct tcccgtgaag
     2941 ccctcggctt cccgatgtgc aacaaagata agtaagaggc ggctatgtct gagaaaactt
     3001 ttctggtgga aatcggcact gaagagctgc caccaaaagc actgcgcagc ctggctgagt
     3061 cctttgctgc gaactttact gcggagctgg ataacgctgg cctcgcacac ggcaccgttc
     3121 aatggtttgc tgctccgcgt cgtctggcgc tgaaagtagc taacctggcg gaagcgcaac
     3181 cggatcgtga aatcgaaaaa cgcggcccgg cgattgccca ggcgttcgat gctgaaggca
     3241 aaccgagcaa agcagcagaa ggctgggcgc gtggttgcgg tattaccgtt gaccaggctg
     3301 agcgtctgac taccgataaa ggcgaatggc tgctgtatcg cgcctacgtg aagggcgaaa
     3361 gtaccgaagc actgctgccg aatatggtcg cgacctctct ggcgaagcta ccgatcccga
     3421 aactgatgcg ctggggtgca agcgacgtac acttcgtgcg tccggttcac accgtaaccc
     3481 tgctgctggg cgacaaagtc attccggcta ctattctggg cattcagtcc gatcgcgtga
     3541 ttcgcggcca tcgttttatg ggcgagccgg aattcactat tgacaatgcc gatcagtatc
     3601 cggaaatact gcgcgagcgc gggaaagtca tcgccgatta cgaagaacgt aaggcgaaga
     3661 ttaaagccga tgccgaagaa gccgcgcgta agatcggcgg taacgctgac ttaagcgaaa
     3721 gtttgctgga agaagtggct tcgctagtgg agtggccggt cgtactgacc gcgaaatttg
     3781 aagagaaatt cctcgctgtg ccgtctgaag cgctggttta caccatgaaa ggtgaccaga
     3841 aatacttccc ggtgtatgcg aacgacggca aactgctgcc gaactttatc ttcgttgcca
     3901 acattgaatc gaaagatcca cagcaaatta tctctggtaa cgagaaagtc gttcgtccac
     3961 gtctggcaga tgccgagttc ttcttcaaca ccgaccgtaa aaaacgtctg gaagataacc
     4021 tgccgcgcct gcaaaccgtg ctgttccagc aacagctggg tacgctgcgc gacaaaactg
     4081 atcgcatcca ggctctggct ggctggattg ctgaacagat tggtgctgac gttaatcacg
     4141 ctacccgtgc gggcctgctg tctaagtgtg acctgatgac caacatggtc ttcgagttca
     4201 ccgacaccca gggcgttatg gggatgcact acgcgcgtca cgatggcgaa gcggaagatg
     4261 tcgcggtggc gttgaacgag cagtatcagc cgcgttttgc tggtgatgac ctgccgtcca
     4321 acccagtggc ttgtgcgctg gcgattgctg acaagatgga taccctggcg ggtatcttcg
     4381 gtatcggtca gcatccgaaa ggtgacaaag acccatttgc gctgcgtcgt gccgcacttg
     4441 gcgtgctgcg tattatcgtt gagaagaacc tcaaccttga tctgcaaacg ctgaccgaag
     4501 aagccgtgcg tctgtatggc gataagctga ctaacgccag cgtggttgat gatgtcatcg
     4561 actttatgct gggccgtttc cgcgcatggt atcaggacga aggttactcc gtcgacacca
     4621 tccaggctgt actggcgcgt cgtccgaccc gtccggcaga ttttgatgcc cgcatgaagg
     4681 cggtgtctca tttccgcacc ctggaagaag cctctgcgct ggcggcggcg aacaagcgcg
     4741 tctccaacat cctggcgaaa gccactgagc cgctgaacga tatcgtccac gcctccgtac
     4801 tgaaagaagc ggcggaaatt gagttggcca gacatctggt tgtgctgcgt gataagcttc
     4861 agccgtactt tgccgatggt cgttatcagg aagcgttgat tgagctggcg gcactgcgcg
     4921 cgccggtgga tgaattcttc gaaaatgtca tggtgaacgc ggaagagaaa gatatccgta
     4981 tcaaccgcct gacgctgttg tcgaaactac gcgaactgtt cctgcaggtt gcggatattt
     5041 cgttactgca ataagcgttc agttaaataa acaaaaacct gctctcgggc aggttttttt
     5101 ataacataaa tagtattagt tgattcgcta ataattctgt aactcataga cgcggttatc
     5161 tctattgatt ggcaagaatt atttcaggaa tacattaacg ctggcggtac ggatattggc
     5221 gttagaatag ctgcgggtgc ttgagactgt ttgtctcagg tattcaccaa aaggcagaca
     5281 gagaaaatcc ccacctgact atacccaaaa taattcgagt tgcttaaagg cggcaaggga
     5341 gtgagtcccc aggagcatag ataactatgt gactggggtg agcgagcgta gccaacacat
     5401 aagcaacttg aagtatgaag ggtatataaa tcaaaagtgc actgcgccca ttattgatct
     5461 cttcaataac gaagcgatct cctgcagtat ttcagaacgt ccaactatgc cgatgatcga
     5521 tgacatgctc atgaaggcat ttgccagact tgatgcgggt accaatccgg ttcttcattc
     5581 agatcagggc tggcaatacc gtcattgatg gtaccagtat cagttacgag agtttggcat
     5641 catccaaagt atgtcccgca aaggcaactg ccttgataat gcctgtgcag aatttttttt
     5701 cggcacttta aaatcagaaa gtttttacac cagtaaattt aaggatattg atgaacttaa
     5761 gatagctatt gaggattaca tacgatacta caatacccga cgaattagcc ttagatttaa
     5821 cggactcagc ccggttgaat accgcctaaa gagctatcca ggcagaaatt aacaaggtct
     5881 gtacagggat gctatcagga aacctgaacg ttggtggata cgctcacgta aatgtctgct
     5941 atgagcgagg agcggacgcc ctatttcaca aaaattagta ttgttctaca agtaactctc
     6001 acaatgaggt tttatgaaaa tcagaaggtt cagtaatggg gatgaaatat cgttattcag
     6061 agtttttttc tcatctgtac atacgatcgc atcacactac tacacacgtg aacaaattga
     6121 tgcttgggcc ccagcagata tcgacctgga gcgatgggcc aatcacatta aggaattaca
     6181 accttttgtt gtagagctgg atggtgaaat agctggatat gcagatgttc aaccaaatgg
     6241 atacattgat catttctttg tatcaggaac ctattcaaga cagggggtag ggacactact
     6301 gatgaattgc attcatgagg aagccagaca gcgtggaatt agtgaactta cttcaaatgt
     6361 aagtaaggct gcggaagtgt tctttctacg acacggcttt catatagtgg agcgaggctt
     6421 tcctatttgc cgtggagtga cattacaaaa tgctctgatg agaaaatgtt tggcgaaata
     6481 atagtcagcc tgcagaaagg cagcattgtt cttttgcctt gttgaactca gtaaaccgct
     6541 acaatgagca acgtccgctg ctggcgcaaa gcggacatca gtattcaaaa aatgaaaaac
     6601 gacgacttga tgtatatcgt ttgctataca tggtggttgt gctattcttg taaagcaaat
     6661 gctatacaag gggtgtctca tgaaatcaga tgttcaactt aaccttagag ctaaggagtc
     6721 gcagcgggcg ctcattgatg cagctgcgga aatccttcac aagtcacgta cagatttcat
     6781 tctggaaacg gcctgccggg ctgccgagaa tgtgatcctt gaccgccgtg tatttaactt
     6841 taacgatgag caatatgagg agttcatcaa tctgcttgat gcaccggtcg cagatgatcc
     6901 cgttatcgaa aaactgctgg caaggaaacc tcagtgggac gtgtaacagc accagaacct
     6961 ttgtccgctt ttcatcaggt agctgagttc gtcagcggtg aggctgtgct cgatgactgg
     7021 ttgaagcaaa agggcctcaa aaaccaggct ctcggagcgg ccagaacatt tgtggtgtgc
     7081 aagaaagaca cgaagcaagt agccggtttt tactctctgg ccaccggtag cgtcaaccat
     7141 acagaagcga caggcaacct tcggcgtaac atgccagatc ccatccctgt cattatactt
     7201 gcccgtcttg ctgtcgatct ctcattccat ggaaaagggc ttggggctga tttacttcat
     7261 gatgcagtgc ttcgttgcta tcgggttgcc gagaatattg gtgtacgtgc aatcatggtt
     7321 catgcactta ccgaagacgc caaaaatttc tacattcacc atggtttcaa atcatcacaa
     7381 actcagcagc gaacattgtt ccttaggctc cctcaataga atgcaaagac tgttatgttc
     7441 aaatcgctat aagcgataat ttgatagaac gtctaaggtt aaattcagga agaatacgac
     7501 gaacaaaata ttgatgagac aggaatccgc gtgatgcaag aaagcaacgg aatggataat
     7561 ccgattgcgg acaatgttat ttagttatag ccagaaacaa aaaagagccc atgtattaaa
     7621 tggactcttt cgctgatgcc tcggttaatc tgtccaggtt ttggggtcag tacaaagtga
     7681 gcccacctct gccattcttg tggcgttatg cattctcaag gcactctgtt aattttatct
     7741 tgttggcgtt ttataggccc gataacccat tatgttatcg ggcatttttt taacgtaatg
     7801 gtaattccgt cagacaggtc tggctgtcat ctctggtggc aatggcatgt gacgccgttt
     7861 taccgttgta gcttacttcg agcgtccctt ccatattgcg cggtagccaa acaccgataa
     7921 atccgtttcg atagctttgc atctcttttt gtacgatgac agcgccttta ctgtctgtca
     7981 cttttacagt gaacggttta ttcggcattt ctccctgaca gccggaaagg ctgtggttaa
     8041 aacaggggtg tgtccgccat tcatagggcg caaaagagag atagaatttg tcgcctaacg
     8101 gtagcgtata aatctgctct ccgtcagata atttgagctc ggtactggta atcgacgcgg
     8161 agtaaggcaa aggacggctc tgcggcgtct gatcaatcgt atccacgatc tgctcaaccg
     8221 tttttcccgc cagcccatgt tgcgccagaa aagcggattc tgaggatgcc gcaagcgcgg
     8281 agccgctggc gcataaaccc aaaagtaata accatgatga tttcgacata acttcaattc
     8341 cttgtgaaca atctccttgc ctactatagg ggttccccta agggaaaggt caaagggacg
     8401 cagggtaaag taatgcaaag ttatgctggg gggggagatg gggaattgga ataaaaaaaa
     8461 tccccgccat caggcaggga ttcaaaattc tgagcttttt aagcttacag gctggttacg
     8521 ttgccagctg ccgggccttt agcgccgctt tcgatggtga aggaaacttt ctgaccttcg
     8581 tccagagatt tgtaaccatc gttctgaata gcggagaagt gtacgaacac gtctttagaa
     8641 ccgtcatcag gagtaataaa gccgaagcct ttatcagcgt tgaaccattt tacgatacca
     8701 gtcattttac cggacatagt gtattacctt ttaaaaaata agtgtgcctt tcggcgttat
     8761 ggcgtgcttt acagattttt taagcgttaa ggaaatgcgc actacgaggg gtatctaatg
     8821 gataactctt gaagggactt gccttactaa actgctttaa tggtctgtac gtcaaaccgt
     8881 tgagcacatt aactcatgta atgccgggcg atgcaacttt tattttactt tatttctcca
     8941 ggccagtaat cgggcggggg aaacggccct tacgcaggac cgttaaaaca gaaaggggta
     9001 aaaattgctc catcaattgc ttacttaagc gtgggttcgc ctgtatcagg cgcatcaatt
     9061 tgagctctgc tggcgtgggt ttttcgcgtt tcgattccca ttcctgaacc atggcaaccg
     9121 ttacgcccag cgctctggcg aattcatctg tttttagtcc cgttcctctc cgtaactgtt
     9181 caaattcggt aaaaggattg ggtttttgcg tcagggtgat ctttcgtgtt tcatctttaa
     9241 aaacaatttg ttccaggctg ctcagcagct caaacatcgg atctttatat tccattgaga
     9301 actcctgtaa atcacacagc gggatcgtga aatgcatcga agcctcttaa gaatagtcgg
     9361 gaaacttgcg ggtggggggc gacgcgccgc caggaagcgc tatcgattcg tttcgatgcc
     9421 ttacgctacg cgacttttag gacgctaaca atttgatcca ggaagatata tccgtctttc
     9481 agaaaataat tgtaaagatt aaaaaaatat tacatccccc gctggaaagc tttcttgccg
     9541 cgttttttat cgcagtgtca ggttaaaaat taacaataaa ataataaatt aagcattgat
     9601 gcagataaac ataattttcc gctacaagat cgcgtggaaa gggtatcctg caagcctgac
     9661 ctggactatc cttgtaagcc gtcaggcacg caggtgtcgt tgtgcgcatt tttgggtgaa
     9721 aggagtatta acaatggcga caggtaagtc ctgctctcgc tggtttgcgc ctgttgtggc
     9781 gttattaatg gtgtttagcc tgagcgggtg ttttgataaa gaaggcgatc agcgcaaagc
     9841 gtttgtcgat ttcctgcaga atacagcaat gcgtagcgga gagcgtttac caacgctgac
     9901 ggccgatcag aaaaagcagt ttggtccgtt cgtgtctgat tacgcgatac tgtatggcta
     9961 ctcgcagcag gtaaaccagg cgatggattc cggtctgcgc ccggtggtcg atagcgttaa
    10021 cgccatccgc gttccgcagg attatatgac gcaacgcgag ccgctgcggc aggcaaatgg
    10081 ttcgttaggc gtgctggcgc aacagttgca gaatgcaaaa ctgcaggctg atgccgcgca
    10141 tggcgcgtta aagcaggccg atgacctgaa acctgtgttt gatcaggtct acaaaaaagt
    10201 ggtcaccgtg ccggcagatg ctttgcagcc gctgatcccg gcggcgcaga tctttacgca
    10261 gcagttggta caagtgggcg attatattgc gcaacagggc gagcaggtga gctttgtcgc
    10321 gaacggcatt cagttcccga cctcacagca ggccagccaa tataatgcgc tgattgggcc
    10381 gttggcctcg cagcatcagg cgtttaatca ggcctggacg gcggcggtaa acgcgaccca
    10441 gtaatgacag tctgcccgat aagcgcaagc cagcgcttat cgggcctgta gcgttatccc
    10501 gccgcttgcg gattgacgca gttcttctct atttttccct gcagcgcatc aatcaaatta
    10561 tccaccgcac aggccatcat gttgtagcgc gtctcatgcg ttgccgagcc aatatgcggc
    10621 accgcgacga cattagacat gttcagcagg ggcgaatcca cagatagcgg ttcctgttca
    10681 aagacatcca gacctgccgc atatatttca ccgttttgca gcgcggcaat cagcgcgttt
    10741 tcatcgacca ccgggccgcg tccggcatta ataaaaatgg cggacgattt cattctggca
    10801 aactgtgttg cgccaaacag atgtcgcgtt tctgccgtta gtggcaggat cacgcagaca
    10861 aaatcggcct cctgcaacaa cgtatccaga tcgcagtagc gggcgttaaa ccggtcttcc
    10921 gcctcctgat gccgccgacg ggcgtgatag agaaccggca tggtaaaccc aaagtgcgct
    10981 cgctgcgcca gcgccatccc gatacgcccc atcccaacga taccgagtgt tttgtgatgc
    11041 acatcgacgc caaaccatgc cgggccaatg ctttctgtcc attcacccgc cttaacccgt
    11101 tctgcgacgt ccaccacgcg gcgggcagtg gccagcatca acgccatcac cgtatcggca
    11161 acggtttccg tcaaaacggc aggcgtgtgc atcaggacta ttttgcgggc agtaagggcg
    11221 tccacctcga cattatcgta tcccaccgag atggtcgacg ccgcgcgtag cgccggcatt
    11281 ttttccagca gcgcgcggtt aacggtttcg ctggtgccca gaaggccttg cgcgctggca
    11341 aatgcctgcg cgtgtcgcgc gaccgtttcc ggatgcaggt tcggtacctg ggtgacggta
    11401 aaatgcgcct ccaggcgatg cagcaaatca tcaggcaggg ttttgtagag aatgatggac
    11461 ggcttcatgc gactctccgt aaatcaaaag gtaagcgcgg catgcgccaa ccggaacagg
    11521 cttattatta acccgtttag ccatcatcga ccagccgatt tccccgctgt cggcagccgt
    11581 gtcgtggtaa atagtgaatg aatactgaat aatgcgacgt gtatccggtc tggcgaggga
    11641 ataatgcagg ccgggtaaag catgccgcct tacccggtac ggtagtttac tgcaatggac
    11701 tcaaggtaat ttcgacgcgg cggttttgcg ccttaccttc tgccgtactg ttgctggcga
    11761 tcgggttcgc cggacccatt ccgctggtac ggatacggct ggcgtcgacg ccctgggtga
    11821 tcagcgaact ggcgacggag tcagcacgct gctgcgacag acgcatattc agatcgtggc
    11881 taccggtact gtcggtgtag cccaccacat tgacggcggt cttgggatac tctttcagca
    11941 ccatcgccac gccggtcagc gtgttagcgc ctgccggttt cagcgtcgcg ctgctgctgt
    12001 cgaaggtgac attattcggc atattcagaa tgatattatc gccgcttcgc gtcacgctaa
    12061 cgcctgtgcc ccgcattttg tcacgcagtt tcgcttcctg tacgtccatg tagtaaccca
    12121 cgccgccgcc cagcgccgcg ccagccgccg cgccaatcag cgcgccttta ccgcgatctt
    12181 ttttggagga ggagagcgcg ccgatgcctg cgccgaccag cgatccaata cccgcgccaa
    12241 tgccggattt acctgcttcg cgttcgccgg tgtaagggtt tgttgtgcag ccagatactg
    12301 ccagggcgcc gctcacgatg gcagcaatca caaatacacg ttttttcatc ttaaatcctt
    12361 atcacttttt tatttttacc acagcgaccg tggcggttga ttatgacgtc tgcacatgaa
    12421 gaaaattcca gggaaaactc tgaaatttgt aagtaacatt gatcggcaaa ataaataatc
    12481 ccaataattc aggagcgaac cttgacccac gcaccatcgc gtcattcggt attgaccgcc
    12541 gcacactggg ggccagtccg tgttgaaacc gacggagaac gcatttttgc ttcatatggc
    12601 gaactcccga cggcacacca gaactccctg caaaccgttg tgcatgacca ggtacacagc
    12661 aaaacgcggg ttcgcttccc gatggtgcgt aaagggttcc tggcttctcc cgataagccg
    12721 caaggcatac gcgggcagga tgagtttgtt cgcgtaagtt gggatgacgc gctggatctg
    12781 atccacgctc agcacaaacg tattcgtgaa agttatggac catcgtccat cttcgccggc
    12841 tcctacggtt ggcgttcgaa cggcgtattg cataaagcgg ctacgctatt gcagcgttac
    12901 atggcgctgg cgggagggta taccggccat cttggcgatt attccaccgg cgcggcgcag
    12961 gctatcatgc cttatgtggt gggtggtaac gaggtttacc agcagcagac tagctggccg
    13021 gtggtgctgg aacatagcga ggtggtggtg ctctggagcg cgaacccgct gaatactctg
    13081 aaaattgcct ggaacgcctc ggatgaacag gggctcgact attttgcggc gctgcgacaa
    13141 agcggcaaac gcctgatctg catcgatccg atgcgatcgg aaagcgtcga cttttttggc
    13201 gataagatgg agtggatcgc cccacatatg ggcaccgatg tggcgttaat gctggggatc
    13261 gctcatacgc tggtggaaaa cggttggcag gatgaagcgt tccttgcccg ctgcacgacg
    13321 ggctatgacc gcttcgctga ctatcttttg ggcacgaccg acggtacggc caaaacagcg
    13381 gaatgggcgg cggaaatttg cggcgtttct gcggtgaaaa tccgcgaact ggcggaaata
    13441 tttcatcata acaccaccat gttgatggct ggttggggaa tgcagcgtca gcagttcggc
    13501 gagcaaaagc actggatgat cgttacgctg gccgcaatgc tggggcaaat tggtacgcct
    13561 ggcggcgggt ttggtttttc ttatcatttt gctaacggcg gaaacccgac gcgccgcgcc
    13621 gccgtgttag cgtcgataca ggggagcatc cctggcgggg tcgatgcggt agataaaata
    13681 ccggtggcgc gtattgtcga ggcgctggaa aaccccggtg ggttttacca acacaatggg
    13741 atggatcgcc gcttcccgga tattcgtttt atctggtggg cgggtggcgc gaactttacc
    13801 catcatcagg ataccaaccg tctgattcgt gcgtggcaaa aaccggaact ggtcgttatc
    13861 tcggaatgtt tctggacggc cgccgcgaaa cacgcggata tcgttctgcc cgcgaccacc
    13921 agctatgagc gtaacgattt aaccatgacc ggcgactata gcaatcagca tttggcgccg
    13981 atgaagcagg tcgtgtcgcc ccggtgggag gcgcggaatg attttgacgt ttttgctgaa
    14041 ctgagcgaac ggtgggaagc cggcggttat gctcggttca ccgaaggaaa aagcgagctg
    14101 gcgtggctgg agaccttcta caatattgcc gcccagcgtg gcgccagcca gggggtgacg
    14161 ctgccgccgt ttgccgcatt ctggcaggct aaccgtttac tggagatgcc ggaaaatccc
    14221 gccaacgcgc agtttgtgcg cttcgcggat tttcgccgcg atcctgataa ccatccgcta
    14281 aaaacggcca gcggcaaaat cgaaatctat tctgcgcgca ttgccagcta tggttatgcg
    14341 gattgtcccg gtcatccgat gtggctggcg ccggatgagt ggcacgggaa cgccgatgcg
    14401 gggcaggttc agctactttc cgcgcatccg gcgcaccgtc tgcatagcca gctcaactac
    14461 agttcgttac gggagcggta tgcggtagcc ggacgcgaac cggtaacgat tcatccgcag
    14521 gatgcgacaa cacgcggaat cgtcgatggc gatacggtac gcgtctggaa tcatcgcggg
    14581 caggttctgg cgggcgcggt cgttaccgac ggaattcggc ctggcgttat ctgtattcac
    14641 gaaggcgcat ggccggaccc tgaacctacc gcaggcggca tatgcaaaaa cggcgcggta
    14701 aacgtcctga caaaagatct tcccagttcc cggctgggga acggttgtgc gggcaacacc
    14761 gcgctggtct ggtttgagaa atataccggc ccggcgctac cgcttacggc gtttgatccg
    14821 cctgccaact cataatccag gtggggtggg aggtatcctc ctgccaggcg ctatcttcaa
    14881 tacgaaaacc gagcgcatgg tagaagttta cggcggattg atttttctgg taaacctcaa
    14941 ggctcagcag aggaaaacgt tgctggacat attccagaag cgctttgcca atgccgtgtc
    15001 ttaacgcgtc gggggcgaca aacagcgccc cgacaaaacg ggcttccagt acgctgacga
    15061 agcctttcag ttgcccattt tcctcccata cccaggtttg cgcggcgggt aaatagacgt
    15121 cgcgtacaat tgcttcgctc tcgtgccagt aacgttcttc gataaaggga tgggcataaa
    15181 tggtactttt catccacagc gccagaatag acgccatgtc ttcactctgg gatttgcgaa
    15241 tcatgttttt ctcccggatg gcaaaaacag ccggtaatat ggtcgttgac cagtccgcac
    15301 gcctgcataa aggagtaaca gatagtcgta ccgacaaact tgaaaccgcg ttttttcaat
    15361 gccttagcaa gcgcatcgga cgcaggtgtt gaggtgggga tcttatccag gctggccgcc
    15421 tgggtgatct gcggctgacc atcaacgaat gaccagacaa aatcggcgaa agactcgccg
    15481 ttttgctcca tcgcaagcca ggcgcgggcg ttactgataa tggcctgaat tttaccgcga
    15541 tgtcgtatga tgcccgtgtt ctgtagcagg cgttcaacat cctcctcctg catagctgcg
    15601 atgcgtatcg ggtcaaactg atgaaaacag gcgcggtagt tctccctctt tttaagcacg
    15661 gtgatccagg ataaaccggc ctgttgacct tcaagacaga tcatttcaaa cagctttctg
    15721 ctgtcagttt ccggtacgcc ccactcgtta tcatgatagg caatataaag ggggtcctgg
    15781 ctgacccagt cgcaacgctg catagacttc ctcgttattg tggttaccgc gaaaatttcc
    15841 ttcaacccgc cttgacgggt ccgctaaaag gacaatagtt aatacagggc tgatgtccga
    15901 catccttcat tcaatgacaa taatatcgcc gaattcggct ctactctgga gtcgcgttga
    15961 tgattgtaag aaaacgccgt ggtcgccgga cattgcgttg tctggcgggc cttatggcct
    16021 gctcgttttt tatcaatacc acgtatgcct ggcaacaaga atatatcgct gaagcggctc
    16081 cggggcatac gacggaacgc tatacctggg acagcgatca ccaaccgaat tacaacgaca
    16141 tactggccga acgtattcag tctacgcaaa atacggtggg tccggtgctt agcctggcgg
    16201 atgaaacccc gcttgatgcg accagcggta tcagtatggg ctggaatttt tcgctttccc
    16261 gacgcgtaac cactgggccg gtcgcggcgc tgcattacga cggttcgacg tcatcaatgt
    16321 ataacgaata tggcgatagc gcgacgacat tagcgcttac cgatccgtta tggcatgcca
    16381 gcgtcagtac gttaggctgg cgggtaaact cgcagttcgg cgatgtccgt ccctgggcgc
    16441 agatcagcta taaccaacag tttggggaaa atatctggaa agcgcagtcc gggttgagtc
    16501 gtatgaccgc aggaaatcag gcgggaaact ggctggatgt caccgtaggc gcggacgtgt
    16561 tacttaaccc gcacctggcg gcgtatgcgg cgttttctca ggcggaaaac agcgctacgg
    16621 atagcgatta tttgtatacc ctgggggtga gcgccaggtt ttaacgggat aaaccgtcgc
    16681 ctggacttat tagaagttca gctaataccc tatctatata tttacaaaaa tatataggtc
    16741 aatcacattc tctatagaca ctttttgcgc ttcctgtggt ctacttagcc gcgctggtag
    16801 actttctcac atctgcgtta gccgcatatt tacctgtttg attaaagaat cgttgtacag
    16861 gtcgttttta tcccgattcc cagggtttgt ttgcatgaga tacattaaat cgatgacgca
    16921 gcagaaactt agtttcttgc ttgcgctcta tatcggtctg tttatgaatt gcgccgtgtt
    16981 ttaccgccgt ttcggcagtt atgcgcaaga atttaccatt tggaaaggcc tttccgcagt
    17041 tgtcgaactt ggcgccacgg tgctggtcac tttcttctta cttcgtcttc tttcactgtt
    17101 tggccgacgc gtctggcgcg tgctggccac gctggtggtg ctgttttccg ctggcgccag
    17161 ttattacatg accttcctga acgtggtgat tggctacggc attattgcgt ctgttatgac
    17221 caccgatatc gatctctcga aagaggtggt ggggctgcac tttgtattgt ggctgattgc
    17281 cgtgagcgtg cttccgctca tctttatctg gagtaaccac tgtcgctaca cgttgttgcg
    17341 ccagctacgt acgccggggc agcgttttcg cagcgccgct gtagtgatac tcgcaggcgt
    17401 aatggtgtgg gcgcctatcc gcctgctgga tgtacagcag aaaaagtttg aacgggcgac
    17461 aggcatcgac ttacccagct atggcggcgt ggtggcgaac tcctacctgc cctcaaactg
    17521 gttatctgcg ttagggctgt atgcctgggc gcaggtagat gagtcgtcgg acaataattc
    17581 gttaataaac ccggccagga aatttaccta tgttgcgccg aaagatgggg atgacaccta
    17641 cgtcgttttc attatcggtg agacgacccg ttgggatcac atggggattt tcggctacga
    17701 gcgtaatacc acgccgaagc tttctttacg ctgtatgttt gtacgggaag gtggggcgga
    17761 taataacccg cagcgtacgt taaaagagca gaatgttttt gccgtactca aacagctcgg
    17821 attcagttcc gatctgtacg ccatgcagag cgagatgtgg ttctatagca ataccatggc
    17881 ggataatatc tcttaccgcg agcagattgg cgccgagccg cgtaaccgcg gtaaaacggt
    17941 ggatgacatg ctgttgattg atgagatgca gaactcgctt gcccagaatc cggagggtaa
    18001 gcatctgatt atcctgcata ccaagggatc gcattttaac tatacgcagc gttatccgcg
    18061 cagctacgct caatggaagc ccgaatgtat tggggtcgat agcggctgca cgaaagcgca
    18121 gatgatcaac tcttacgata actccgtgac ctatgttgat cactttatta ccagtgtgtt
    18181 cgatcagcta cgtgataaaa aagcgattgt gttctacgcg gctgaccacg gcgagtcgat
    18241 taacgaacgc gaacatttgc acggtacgcc gcgcaatatg gcgccgccgg agcaattccg
    18301 tgttccgatg ctggtatgga tgtcggataa atatcttgcc agtccgcaac atgcgcagat
    18361 gtccgctcac ctgaaacagc aggcggagat caaagtgccg cgtcgtcatg tggaactgta
    18421 cgatacgata atgggctgcc tggggtatac atcgccgaat ggcggcatta accagaacaa
    18481 caactggtgc catattcccg atgcgcagaa agtcgccgcg aagtaggttg tctgccgact
    18541 ttctcgccga ttgaattgta ttttgcgact aagggattga cgggcgtgcg cctgagcagt
    18601 aagatgcgcc cgcattcggt gattggcgca gcctggtagc gcacttcgtt cgggacgaag
    18661 gggtcggagg ttcgaatcct ctatcaccga ccaaattcag aaaccctgct cagcgagcag
    18721 ggttttttgt atctgaagcc tgacgaggat gagaacctcc gggggcaaga ggttcgactc
    18781 gagcgaagcg agagaacgtt gcgtcagcaa cggcccgcag tggcaagtca tcctctgtca
    18841 ccggcaggtt gacgctcgca ccaccagttc aggcatgatc ccgtcgctgt agctgacctt
    18901 ctcacccgac agaacggcaa acaggagtgt gattgcctgt cgcgccacct catcaagatg
    18961 catattcact gccgtcagcg gcggcagcga ttcgcgcgcg cggataccgt catagcgagt
    19021 aaccacccgt atttgttcag gtatggcgat gtcttgttcc tggaaagccc gtaccgcgcc
    19081 gctggcaaag gtatctatca gcaccagcac gccgtcaacg tcgggatgcg cctgtaatag
    19141 ctgctgcgcg gcctggtagc cggcattttc accctcgctt tcattgagag agtagacgac
    19201 ggggtcctgg cgccccgcgc accagcgctg gtaagccgct tcgctctcta gaactgatgt
    19261 tcgccgtgtg ttaccgacaa ataacgcaca tttgctggca ccggaggcct ccagatgcgt
    19321 tagcagaagc tgtgctgttg ccgccgagtg cagctcaacc cacggcacag gcgtgtcggt
    19381 ccccggcgtg cggccaatgg tgacgcaggg aatgcccgct tgcgccagcg cctggagctg
    19441 cgggtcgttc tccgccggct caatcaggat cgccgcgtca aagctgacgg catccagtgg
    19501 atttacccct ggtggcacca gaatcagcgc atgctgtttt tccagcgcca tcatcgcgga
    19561 cgttaacgcc acctccatca taaatcccag tcgtgatgcg ccggaggcaa tcgccagcgg
    19621 caccgaagag agcaaagcaa tggtattggt tttgccggtt cgtaactggc gagcgcgaat
    19681 attcggcgtg tagttgagcg caacaatggc ctcttcaata cgccgtcgcg tctgcggctc
    19741 gacaaagcgg gtgttgtgca atgcattgga taccgtccct ggcgagacgc ctgcatggcg
    19801 ggcaacatca atcaactttg cgcgtttttt attttgaaca gccatctgct tcctgacctg
    19861 cgaaaatttg cgcacagggt agcatattta ccagacggta acgtttgctt tttttcggtg
    19921 gtgatcgtaa aaaactcttc attaaaacgt tttaatggag tattttggcg caaatctatt
    19981 cctcaggagg cgatgtggca cacttaactc aggattcgac tttcaccctt ggacgccgtc
    20041 cggcgggcct tatctacgct gataaggcga agagctttgg cggctatacg ctttttgcgc
    20101 cgcaaaccgc cgaagggcgg gtttacctgg tggacgagca gggcgaagtc gcgcatcagt
    20161 ggcagcttcc ggttcgcgcc gggcgtgatg cggtgctgct gccgaacggt aatctgggtt
    20221 ataacggcag ccaccgcact tcagcgaacc tctatccggc gtgggatctc tggcacggcg
    20281 gcgacttcta cgaagtgacg ccggataacg aaatcgtctg gcattacgaa gatatttacc
    20341 atcaccatga tgcgcaatgg ttggcgaacg gtaatctgct gtataccgcc gcgtcgccgt
    20401 tacctgccga tatcgccgcc cgtgttaccg gcggcgaccc gcgccgcgat gcgccggacg
    20461 gcgtgattca gagcgacgtc gtcaaagagg tcaatcgcga cggtgaagtg gtgtgggaat
    20521 ggcgtgcctg ggagcatttg aatccggaag atttcccgat tcatgatatt ttcgaccgcc
    20581 gccactggcc gatgattaac ggcctgtccg tcacccgtga tggcctggta ctgatgagcc
    20641 tgcgtaccac ttccggcgtc attgccgtgg ataaagagag cgggaaggtt atctggcatg
    20701 cagggccgga agtggtagcg cagcagcaca cgccggttga gatggagaac gggtcgattc
    20761 tggttttcga taacggcaac ctgcgtcccg gcgtcacctc gccgcattcc acggtgctgg
    20821 agttcgatcc gcagatcaaa gcgattacct ggcagtatcg cgatatcttc ccgccggcgt
    20881 ttttctcgcc gtatatgggg agcgcgcagc ggctggcgaa cggcaacacc tttatctgtg
    20941 aatcggcgtt tggccgcctg tttgaagtta ccccggaagg cgaaacggta tgggaatata
    21001 tcattccgtt ctttaatgaa tatccggagc acctcagtaa aggcattatt cctggaaaac
    21061 agaacagcgc cttccgtgcg catcgctatg ccgctgatgc cattagttgg ttgaaataat
    21121 gcagaccgcc agcccgcgct ggcggttatt tttttgatgt tttatgggag ttaatcatgc
    21181 cgcagcctgg ccttactacg ccggataacg atgcattacc ctggcaaacc accttacttt
    21241 tggcgcttca gcatgtgctg gtcgttgccg ccacccccat tacctccgtc tttctgatcg
    21301 ccaaagcgct ccactttacc gatacggtga ccgcctcggt acttagcgcg acctttctga
    21361 tgtgcggtct gggcgctatt ctgcaaagcc tgggtgtgaa aggggtgggc gcgcgtttgc
    21421 cgtttattat ggtaccgggg ggcgcgccga ttgcgatttt cgttgcgatc gctttacaga
    21481 ccaatatcca gaccgcgatt ggcgccgtaa ttctgacctc gctgttctac tttatcgcgt
    21541 tgccgatttt ccgccgctgc ctgcaccatt ttcccccctt tatcattggc atcatgctgc
    21601 taatggtgtc gattaacctt attcgcctgt acggcgggtt gatcattggc cagccaggga
    21661 gcgccgactt cgctcatcca accagtatca ttttatcgct ggggactatc ctgataacgc
    21721 tgattttcgc gctggcgttt agcggtattt tgcgccagct ggcggtgatg ttcggccttt
    21781 tagcggggac gctgctggga atggcgctgg gcagcaccga ttttagcggt gttagtcacg
    21841 ggccgctgtt tagtttccca cagcttttgc cgttcggctg gccgattttt gatctctccg
    21901 cctcgctgcc tttactgatt tacgcggtca tctctatggc tgaagcaact gggcaaacga
    21961 ttgcgaccgc ggaaatagtc aattccacgc aaaatgtgca acaggcgatt ccacgtacca
    22021 ttcgtggtga tgcggtaatg tcgctgctgg ggggattttt ggcacctcct taattatcac
    22081 ctccggcgaa aatattgggg tgatacgcac cactaacgtg aaatcgcgtt tcgtgactgc
    22141 ggctgccgga ggattgttaa tcctgattgc catattcgcg ccgctggtac gtctggcgac
    22201 ctgtctgcca ggttcggtgg tgtgcggtac ggcggtgatt gtcttcagca ttatcggggt
    22261 tatcggcatt gatatgattg cgcgtgagcc actgcatacg ccgggtaaaa cctacgcgct
    22321 ggcgatgggg ctggccatgg gaatgctacc tatactggta cccggcctgt atcagaattt
    22381 cccggcgggc gtacagatgg tctttggcaa cggcatggca gcggggacgt tgacggcgat
    22441 tctggtgaac tcgttgttta actggagcga aaagcgcacg caggccaggg ccaaaagtta
    22501 gtttttgtga tcgcggtagg ccgcacgacg gcctacttat ttacaatttt gtaacatatt
    22561 cgatggtgtt tttcaatgtc cggatcactc ttctttgcac acggcttatg gataacctca
    22621 gcattttcgc ctgtgcgttt tagcgttagt ggtattaatc gctcagataa tcaacatatc
    22681 gaaagaaatt tttcaattaa tggctaattg ttaatcacta actgttgcaa aatattaagt
    22741 gaataactct gcctttctgc ctgtagcaca aatttccctg ctgaaaatac ccttctgaac
    22801 tttttttaat ctttgtttgt taattctcac cgttgttgta aaagctggtt acctgtattg
    22861 acgttttgac attctattga cagattgtag ggaatgaggg gcattttatg gagaatccgc
    22921 actgcaactc agtcgattat gcgaacggaa tccccacctc tcactactga cctgaccagg
    22981 taaaaaacaa aaaaggccga gcggtaaaag tctttgcaaa gggcaaaaca acatacatca
    23041 caattggagc agaagaatga gtatttcctt gaagaagtca gggatgctga agcttggttt
    23101 gagcctggtg gccatgaccg ttgcagcaag cgtgcaggcc aaaaccctgg tttattgttc
    23161 agaaggctcg ccggaaggct ttaacccaca gctctttacg tctggcacca cctatgatgc
    23221 cagctccgta cctatctata accgtctggt tgaattcaaa accggcacca cggaagtgat
    23281 cccgggtctt gctgagaagt gggatatcag cgaagacggt aaaacctata cgttccacct
    23341 acgtaaaggg gtgaaatggc aatccagcaa ggatttcaaa cccacgcgcg agctgaacgc
    23401 cgatgatgtc gtgttctctt ttgaccggca gaaaaacgag cagaacccgt accataaagt
    23461 gtctggcggc agctatgaat actttgaagg catggggctg ccggatctga ttagcgaagt
    23521 gaagaaggta gacgatcaca cggtgcagtt tgtgctgacg cgtccggaag cgccgttcct
    23581 tgccgattta gccatggact tcgcctctat tctttccaaa gaatatgctg acaacatgct
    23641 gaaagccggt acgccggaaa aagtggatct gaatccggtc ggcactggcc cattccaact
    23701 ggtgcaatat cagaaagatt cccgcattct ctacaaagcc tttgacggct actggggcac
    23761 gaagccgaaa attgaccgcc tggttttctc cattacgcct gacgcctctg tgcgttacgc
    23821 caaactgcag aagaacgaat gtcaggtgat gccgtatccg aacccggcgg atattgcgcg
    23881 catgaaagaa gataaaaaca tcaacctgat ggagcaggcc ggtctgaacg tgggttatct
    23941 ctcctataac gtgcagaaaa aaccgctgga tgacgtcaaa gttcgccagg cgttgaccta
    24001 tgccgtgaat aaagaggcca tcatcaaagc cgtttatcag ggcgcaggcg ttgcggcgaa
    24061 aaacctgatc ccgccgacga tgtggggcta caacgacgat attaaagact acggctacga
    24121 tccggaaaaa gcgaaggcgc tgctgaaaga agccggtctg gaaaaaggct tcaccatcga
    24181 tctatgggcg atgccggtac agcgtcccta taacccgaat gcgcgtcgta tggcggaaat
    24241 gatccaggcg gactgggcga agattggcgt tcaggccaaa attgtcacct atgaatgggg
    24301 cgaatacctc aagcgcgcta aagatggcga gcaccagacg gtgatgatgg gctggaccgg
    24361 cgataatggc gatccggata acttcttcgc cacgctgttc agctgcgatg ccgcccagca
    24421 aggctccaac tattcaaaat ggtgctacaa gccgtttgaa gacctgattc agcctgcgcg
    24481 tgcgaccgat gaccacaaca agcgtattga actctataaa caggcccagg ttgtgatgca
    24541 tgaccaggcg ccagcgctga tcatcgctca ctccacggtt tatgagccag tacgtaaaga
    24601 agttaaaggc tatgtggttg acccattagg caaacatcac ttcgaaaacg tctctgtcga
    24661 ataattaaaa gagcgctgcg ccccggtgtt gtgtaggccg gataagcgca gcgccatccg
    24721 gcgtaatgct ttatccgcga tgcagtttgc gtgggataag atttgtgagc aatacagact
    24781 cacggttcca ggccgtgcgt catgagagag aattcgggtt atgttgcagt tcattctccg
    24841 acgtttggga ctcgttatcc cgacgtttat cggtattacc cttctcacct ttgcctttgt
    24901 ccacatgatc cccggcgatc cggtgatgat catggcgggt gagcgaggta tttcccctga
    24961 gcgtcatgct caactgctgg ctgaactcgg tcttgataaa ccgatgtggc agcagtacct
    25021 ccattatatc tggggggtga tgcatggcga tttaggcatc tcgctgaaaa gccgaatccc
    25081 cgtgtgggac gagttcgtac ctcgctttaa agcgacgctg gaacttggcg tctgcgccat
    25141 gatttttgcc gtcgccgtgg ggattccggt gggcgtgctg gccgcagtga agcgcggttc
    25201 tatcttcgat cacactgccg ttggcctggc gctgaccggt tactctatgc ctatcttctg
    25261 gtggggcatg atgctgatca tgctggtctc cgtccactgg aacctgacgc cggtttccgg
    25321 gcgcgtgagc gatatggtgt tccttgatga taccaatccg ttgacgggct ttatgctgat
    25381 cgacaccgct atctggggcg aagagggtaa ctttattgat gcgctggcgc atatgatcct
    25441 gcctgcgatg gtgctcggca caatcccgct ggccgtcatt gtgcgtatga cccgttcgtc
    25501 gatgctggaa gtgctggggg aggattacat ccgtaccgca cgcgccaaag ggttgaccag
    25561 gatgcgcgtc attatcgtcc atgctctgcg taacgccatg ctgccagtcg tcaccgtgat
    25621 cggcctgcag gtcgggacgc tgttggctgg cgcgattctg acagaaacta tcttctcgtg
    25681 gcccggtctg gggcgctggc tgatcgatgc gctgcaacgc cgcgattatc cggtagtgca
    25741 gggcggcgtg ttactggtag cgacgatgat tattctcgtc aacctgctgg tagacctgct
    25801 gtacggcgtg gtgaacccgc gtattcggca taagaagtaa ggggccatca tgtcacaggt
    25861 tactgaaaat aatgttaatg ccgcaccggc gcccatgacg ccattgcggg agttctggca
    25921 ctatttcaaa cgcaataaag gcgcggtcgt cgggctggcg tatgttctca tcgtgatcct
    25981 gattgcggtg tttgccaact ttattgcgcc gtacaacccg gcagagcagt tccgcgatgc
    26041 gctgctggcg ccgccggtct ggcaggaagg cggcagttgg gcgcatattc tgggaacgga
    26101 tgatgttggt cgcgatgccc tctcgcgcct gatgtatggc gcgcgtttgt cgctgctggt
    26161 cggctgtctg gtggtcgtcc tgtcgctggt catggggatt attctcggcc tagtcgcggg
    26221 ctacttcggc ggtctggtcg ataacatcat catgcgcgtg gtcgatatta tgctggccct
    26281 gccgagcctg ctgctggcgc tggtgctggt ggcgatcttc ggcccctcca tcggcaacgc
    26341 tgcgctggcg ttgacgtttg tggcgctgcc gcactatgtc cgcttaaccc gcgcggcggt
    26401 tctggtagag gtgaaccgcg attatgtgac tgcctcccgc gtggcgggcg caggcgcgat
    26461 gcgtcagatg ttcgtcaata ttttcccgaa ctgccttgcg ccgctgatcg ttcaggcatc
    26521 gctcggtttc tctaacgcca ttctcgatat ggccgccctc ggctttcttg gcatgggcgc
    26581 gcagccgcct acgccggaat ggggcaccat gctctctgat gtattgcagt tcgcgcaaag
    26641 cgcctggtgg gtcgtgacct tcccggggct ggcgattctg ctgacggtac tggcatttaa
    26701 cctgatgggt gacggtctgc gtgacgcgct cgatcccaaa ctgaagcagt aagaggttcg
    26761 agatggcgtt attaaatgta gatcaattat cggtgcactt cggcgacgaa gggacaccgt
    26821 tcaaagccgt cgaccgcatt agctacagcg tgaagcaggg tgaggtggtc ggtattgtcg
    26881 gcgagtctgg ttccggcaaa tccgtcagct cgctggcgat tatggggctt atcgattacc
    26941 caggccgcgt gatggcggaa aacctgctct ttaacggaca ggatctgaag cgcatttccg
    27001 agaaggaacg tcgcaacctg gtgggcgctg aagtggcgat gattttccag gacccgatga
    27061 ccagcctcaa tccttgctat accgttggct ttcagattat ggaagccatc aaggtacatc
    27121 agggcgggaa caagaaaacc cgtcgtcagc gagcgattga cctgttgaac caggtgggta
    27181 ttcccgatcc ggcttctcgt ctggatgtct atccgcacca gctttctggc ggcatgagtc
    27241 agcgcgtgat gattgcgatg gccatagcct gtcgaccaaa gctgttaatt gctgatgaac
    27301 cgaccacggc gctggatgtg accattcagg cgcaaatcat tgagctgctg ctggagttgc
    27361 agcaaaaaga gaacatggcg ctggtgctga ttacccatga cttggcgctg gtggcggaag
    27421 cggcgcacaa aattatcgtc atgtacgccg ggcaggtcgt cgaaaccggc gctgcgcagg
    27481 atattttccg cgcgccgcgt catccgtata cccaggcatt gctacgtgcg ttaccagagt
    27541 ttgcgcaaga taaagcgcgt ctggcgtcgc tgccgggcgt ggtgccgggg aaatatgacc
    27601 gaccgacggg ttgtctgctt aaccctcgct gcccccacgc cacggacaga tgtcgtgcgg
    27661 aagaacctgc tctcaaccaa ctggacgatg gacgtcagtc aaaatgtcat tacccactcg
    27721 atgatgccgg gaggcccaca ctatgagtac gcatgaggcc accttgcaac agccgctgtt
    27781 gcgggctatc gacctgaaaa aacactatcc ggtgaagaag gggatctttt ctccggaacg
    27841 gctggtaaaa gcgctggacg gcgtgtcgtt taatctcgaa cgcggtaaaa cgctggcggt
    27901 agtgggggag tccggttgtg gaaaatccac actgggtcgc ctgctgacga tggttgaaac
    27961 gccaaccggc ggcgagcttt attaccaggg gcaggatctg ctcaaacacg atccgcacgc
    28021 gcagaaactg cggcggcaga aaattcagat tgtgtttcag aacccctacg gttccctgaa
    28081 cccacgcaag aaagtggggc aaattctgga agaaccgttg ctgattaaca cctcgctcag
    28141 caaagagcag cgccgtgaaa aagcgctggc gatgatggcg aaggtggggc tgaaaaccga
    28201 gcactacgac cgctatccgc atatgttctc cggcggccag cgtcagcgta tcgctatcgc
    28261 ccgcggtctg atgcttgatc cggacgtagt gattgccgac gaaccggtct ccgcgctcga
    28321 cgtgtcggtg cgcgctcagg tgctgaacct gatgatggat ttgcaacagg atatggggct
    28381 gtcttatgtc tttatctcgc acgacctgtc ggtggtggag cacattgccg atgaagtaat
    28441 ggtcatgtac ttaggccgct gcgtggagaa agggaccaaa gagcagattt ttaacaatcc
    28501 acgtcatccc tatacccaag cgttgctctc cgccacgccg cggctgaatc cggacgatcg
    28561 ccgtgagcgg attaagctga ccggcgagtt gccgagtccg ctgaacccgc cgccgggctg
    28621 cgccttcaac gcccgctgcc gccgtcgctt cggaccctgt acgcagttac agccgcagct
    28681 taaagagtac gacggccagt tggtggcctg ctttgccgtc gatcaggatg aaaacccgca
    28741 gaagccgctg agttaattgc gttttatgcc ggatggcggc tgcgccttat caagcctaca
    28801 ccttacttgt aggcctggta agcgtagcgc caccgggcat ggctctccgg tacgacttag
    28861 agcctatccc attagggcta ttttacttgc cattttggac ttgggcagtg ctcgccaaaa
    28921 cgcgttagcg ttttgaacgc cgctagcggc ggcccgaagg gcgagcgtag cgagtcaaac
    28981 ctcacgtact acgtgtacgc tccggttttt gcgcgctgtc cgtgtccaaa ctggctgtgc
    29041 caataacgcc tggtgggata ggctcttatt caatcaattt taataacggc gacaggcaca
    29101 acaatattcc atataacaga ataagccagg ttttcaggcc gcgtaatttt tccagttgcg
    29161 ctactttata aatcaggaaa aagggaataa tacacgcgac aatgccataa agcggactgc
    29221 ctaactggaa aaagaccaat actgagacgc gaaacgaaac ccaaataacc agagtaacca
    29281 cgataaagac acagattcca gatgtcagta acagtgggtt gatgtttttg acatccataa
    29341 tgcgactcaa cacattcagt acaatacctt taagcgcttc gtgaaaacct aaataaatac
    29401 caaagaacgc ggtaagtacg gcaaaaatat tgaggatggt agaggtaatg tggatgatct
    29461 ggccagggat tacctgagct gccagcgcaa gagcggaaat attctgctcg aacgctgata
    29521 ccgcctcttc atgactaatc gaaaaggtaa acgaaaacga gaaaaagaga ataatggcaa
    29581 tcagcgtaat atagctaatg cgatgcgtgc gaatcgccat ccgggtggcc agcacacggt
    29641 caggttcgcg cttacgatag gcgatgttca ttgggtttag cacctgaatg aagaccgcag
    29701 aaaagaagca aaatgggata gtgagcagta cgtcgcgaaa gaaaaccgat gcggcgggaa
    29761 aggcggaaat attatcaaga ttccagtgtg ggatcatcgc caaaccgaat atcagaatga
    29821 tcccgacttt taccactacc atcgggccgg aaattttaaa taatagcttt tccccgccgg
    29881 aggcaatcgc caccagcacg gcgaaaatcg cgactttata gataatagac tgcgaaagat
    29941 cggcctcagt aaggccgaag gttttgatat aggaggcgct atcaaacacc accgacaggg
    30001 agtaaataaa caccccgtgg ataatcataa gaaaatagat tacaccgaga aaaacgcccc
    30061 agtttttgcc aagatagtga ctgataatat ccgtataatc gtcacaggtt tcgctttcag
    30121 ataacgtttt tagataaata tcctgcacaa tataggtagc gggataggcg atgataaaag
    30181 cggtaataaa tacccagatc cccttgagac cgatttgcac tggcattaag acggtaccgg
    30241 cgccgattgc cataccgata cacaagagca cccagccaaa atcatatttt gtaaacggta
    30301 atctcgttga aagcggtgtg gtcgtagcgt tactgttatt taatggtaat gtgtcgtcct
    30361 gcatagagcc ccctgcccaa aatatacgca gctctctcat aaagaatgct gcctataacc
    30421 aggctatagt gccttgatac ccgatgcggc aaaccggtga cagcggttcg ccgagcaatc
    30481 gtcagaatgc tgcttttctg ctggcgcgtt caaggtcatg aataatatcg tcgggatctt
    30541 caggtcccgc tgaaagacgg ataagttcgt cggtaatacc tgcttttagc cattcctctg
    30601 gcgcaacagg cgaatatgtc atagacgcag gatgctgaac gagggtttcg gtatcaccgg
    30661 gactggccgc gaggaggcat aatttacaga attgagcggc tgactgccag cctcagaaat
    30721 gctgaatgta ttctggcaaa taaaagtagt cgtctgcgaa gcgtcacgca gattgcacgt
    30781 tagcgccgtg ccgggacggg gattttgccg taatatcagc agcaagccgg gtttacccgg
    30841 tgaggcgcaa tgttgcgggg gcttgagccc cggcggcata ggttgctgga tagagaaaac
    30901 ccccgcacgt tgactggtat aaacctggca acctgacggg ggctaacttg aacccaaaca
    30961 ctttaaagat agccgcgaac ggttgccatt gcaacaaggc ggctatatga cgcttacgca
    31021 gttgggcgtg gccttctggc acgatctggc ggcgccgatc attgctggca ttatcgccag
    31081 tgtgatcgtc aactggctac gtgacaggaa gtaacgcgtt ttgagcgtct gtccgccgta
    31141 atggcaacat gcgcccgagc caggccgcag gggaaacctt gcggcctttt tcggtttact
    31201 gcgggtaagg cacccagtcg ccgccattca gacgaacgta gggcttaccc tggtactgaa
    31261 tcaccaccgc attagcgttt tctgaaaccg gcgcggtttg cggcagattg ctggtcagct
    31321 tgttccagtt cacactgtct tcggtaaaga gcttaccgtc cacggcgcgt acgaccagtt
    31381 cggaaatcgc caggtagctg ctcggctgat taatatcaat cggcgcgccc tcatgcgggg
    31441 ctttcatgcc aaaaaatttc acgcccgccg ggacgttggt gatggagggg ctgggaatat
    31501 cgcgcaggcc tgagatctgc attctgtcgc ccttcagcgc gccgccgtgc tccggtacga
    31561 cgactaccat caccttacgc ccggatttct ccagttcggt aaagaaggcg tccagttcat
    31621 cgaacagttt ctgcgcgcgg attttataat ccgccgtttt gctgacgcca gggaagtggt
    31681 tgccatcgtg cagcggcagc aggttaaaga aagtcgcgga gcgggaattg gcttcacgtt
    31741 cttcccctgt taaccagcgg ttcaggaccg ccagatcgtc atataccggc gagccgtcga
    31801 atgacagcag ggcggttggc aggccggact ggttcatcag ttcgctctgc ataccgccgt
    31861 tttcgcgaac ttctttcagg aagccgccaa attcaccgtt atgatccatc atcagatgct
    31921 gagtaaagcc cagtttcgcc agattatcaa acagataaca ttcgttattg gctggttgat
    31981 aaagtcgggt atgcgaaggt tgaccacagc tggcgcgcag cagacgaatg gccgccgggc
    32041 cgctgtaaga cgtaccggaa ttaaagtgtt taaacaaaat gtcaaagtgc gaccatagcg
    32101 gatgtgacat caggcctgcc gcttcgacat ccgaccagga gagcgaacaa atattgatga
    32161 ccaataggtc gaacggctgc gcatcaggcg gaagctgcgc cgggaacgtc gttttccgct
    32221 tttcttccgc ggcatagaag gtgttcaacc aggcgttcag attcgcggtc gttggcggcg
    32281 cggtttgcgc aggcatatcg ccgatgaccg gcttatcgcc cgctgtcgcg acggtagcgg
    32341 ccgcgttacc gccagtcgtc gtcaccgtat cggttggctg gcctgccggc cacagcgtaa
    32401 aaaccgggcc ggttaatgtc aggacattca gccataccat gatggcgacc acaaacaccg
    32461 taacccgaat ccactgtgat aaaaatagcc aggcaaccag cagtacgaag atggcgccga
    32521 tcatttgcca gttaataaaa cgggcgatca gatcgagcag ataaccggag ctgaattccg
    32581 ccacctgcgt cccctggctc ataatgcttt gcgggccggg cagccaggta tcatgccaga
    32641 acagcgcgaa gccgacggga atggcaatcc agtggcgcaa ccggtgaagg cgatattttg
    32701 gtattggcat gagcagaaac gccatgaata ccagattcag taaaggatga aaattcagat
    32761 agcctgccca cagcaggcca aacttgacca gaaaatagaa gttccagccg gaaagaccgc
    32821 gccagtattg ccagagcgga gaaggcattg aaggagtttg agtatgctga gtcatttttt
    32881 gtctgccttg actttcgtag cgcggcgcag agttccggct ggttttacat aacgaggttt
    32941 ggcaaatagc agccgggtcg tatcactgat acggcgtagc gaatgacgcg ccagataccc
    33001 cagcggaaag aaaatcagcg cgcaaaaaag aataatttgc acgatatcgc tgatggtcat
    33061 catgatgcac gctccgcggt gtcgtcgagc aatcgcaggg gttcaggaat acgacgccag
    33121 atgcggccat cgtgttcggc atttattacc gggtcggcgc gttttgccag cggtagcggc
    33181 gttccccaca gttccggcga caataagcgc atctgcacca gctcggcgct gatttgttta
    33241 tcttcgaacc agaccatacg attagagaaa atatcgcctg tcggcaaagg gaaaatatgg
    33301 tttaacgcgg tatccagatc gttgacccgg cagaatgata aaaacagcac cagacggttg
    33361 ccgccgatgg tcataatatc gccggttcgg cttggtcgac ataatgttaa cgcctgctca
    33421 acccgaatgc ccggcaccgg gcgcagcgcg accagaacgc ctttcccgtc ggcggggagc
    33481 agggtgttgc tcatcatcgt atggatggca tcgcaaaagg tatcccacgg ctgaaaaccg
    33541 cgcagtttca acggttgcgt catcgacagt agcgtggtga tgtcttccgg tacgtaacgg
    33601 ctgaactgct gcccctgcac gctttcaata agcgtcagac agcgtgaaag cggggcgttc
    33661 cagggaatga tcatattcgc gccgcagccc agcagcaggc gctcatcggt ggcgcgcaaa
    33721 ctggcgatat tttcgcgcac gacaattttc agcgcgcttc cccgctggcg tcgcaaagta
    33781 tgaatgcgac gagcaagcgg ttcgatttgg ttgttctgtg taagcgaaaa aataattgtc
    33841 gcggcctgcg ccgtgcgcgc gtcgttgaat agcgcttcgt tattgtcgaa aagcgtccag
    33901 tgttccgaga gcggcggcgc gccttcaagg acggcgacgt ggctaagaat gcgtttttcg
    33961 tcgctacgcg gctgaattgc cgtctcctcc tgatgggata gcgtccagcg ttcgtcctgc
    34021 tgacatagca ataactgctg tcgggcgctg acgccttttt cgttacacca gaaggcaata
    34081 tcgaacaaat gttggtcgcc ctgaaaacgt aaactggcga ggccgaaaag tgagcgatac
    34141 tcgcccatca acaacgagga ctgtttatca ctattattac aaggggtaat aaccaacaat
    34201 gaacagtgat gaaaacgagt ccatttattc attttttcca gccatttatg caggctttct
    34261 gacgttatat tccgccacgt gttatttgca caaataagaa tgaaaaagta atgcgtcggg
    34321 ttaacagaac aaagcaaatc gtggggcaaa gagtatagcc ctttttctga atccggcatg
    34381 gtaaataagc ggattttctc cggaccgtga gattcatcta atttgattac tttgccagga
    34441 tcgccttcca tgccgatgac ggcgacattt gcattctccg tttgtgacgc aatcgtttga
    34501 ttcaccaggc tgatggcatc ttgctggcga tcggcgttaa cccaccagac gccgccggtt
    34561 ggcatatggc gcagttcatc ccataatgat gagatgccga gagaaaatac ggggtccaca
    34621 gtgtccctca tgtcactatt ttaactgttt atcagtttac tagcgaaagc acagaaataa
    34681 acctaacatt gaaattaaaa cgcatcagat ttagcatgtg aatcaatttg tccggcagga
    34741 tgccctgtaa ctctgcgctt tgcattttta cacattataa atgatgtcac ggaaagatga
    34801 aaaatgcgcg ttctcccgta ttgacgacgg ggcgtaatgc tgccagtgag aaatatttaa
    34861 aaaggagcaa ccagaatgta taacaatgaa cctggcgctc agtccgatcc aacgttgggc
    34921 tacacttttc aaaatgattt tctggcatta agccaggcgt tttcactacc cgaaatagat
    34981 tataccgata tttcccaacg cgaacagttg gcggcggcga ttaaaagatg gccgctcctg
    35041 gctgaatttg cgcaaccaca ttcattaagg aagccatgaa tggcgattct gggactgcag
    35101 ggcgtgcgcg gcggggtggg aaccacatct ctcaccgcag cactcgcctg ggcgttacaa
    35161 atcttagggg aaaatgtcct ggtgattgac gccagccccg ataacctgct gcgcatgtcg
    35221 tttaacgtcg acttcgtcca tcagggcggt tgggcgcgat cgttgctgga cggccaggac
    35281 tggcgcgatg ccgggttacg ttatacctcg cagcttgatc tactgccgtt tggacagctc
    35341 acctcgcaag aatgggaaaa tccgcaggcc tggcaggaga cgctgggaga gatcggatcg
    35401 gctatccagg cgctgaaagc gagcgggcgt tatagctgga ttttactgga cttgccctac
    35461 ggcgagtcac cgctgacacg acagctggtg agcctctgcg accatacgct ggcgatagcc
    35521 caggttgacg ctaactgcca tattcgcctt catcagcagg cgttgcctgc cggagcgcat
    35581 attctgatca atgacttacg cattggcagt cagttacagg acgatctgta ccaggtctgg
    35641 ctgcaaagcc agcgccggtt gctgcctatt gtgatccatc gcgatgaagc gatggcggag
    35701 tgcatggcgt cgaaacagcc gttaggcgag tatcgcagcg attcgttagc cgccgaagag
    35761 gtgttaacgc tggcgaactg gtgcctgctg cacgatgcgg gcgacaaaac gtctgccggg
    35821 agcctgcgat gagcgccctt tcccggtggc tgcttatccc gccggttagc gcgcgcttga
    35881 gcgagcgcta tcagggttac cgccgccacg gcgcgtcgcc gtttagcgca gcgctcggct
    35941 gcctgtggac gattctggcg tggatagtgt ttccgcttga gcatccgcgc tggcagcgta
    36001 ttcgcgacgg gcataaagcg ctttatccgc atattaacgc cgcccgcccg cgcccgctgg
    36061 acccggcccg ttacctcatt cagaccctct ggctggtgat gatctcgtcg actaaagaac
    36121 gtcatgaacc gcgctggcgg tcatttgcgc gcctgaagga cgttcgtgga cgttaccatc
    36181 aatggatgga taccttaccg gaacgggtgc gccaaaagac aacgcacctg gaaaaggaaa
    36241 aagagctggg acatcttagc aacggcgccc ggcgttttat tctgggcgtt atcgtgacct
    36301 tttcactgat actggcgctg atctgtatta cgcagccatt taacccgcta tcgcaattta
    36361 tctttctgct gttgctgtgg ggcgttgcgc tgttggtacg acgtatgccg ggacgctttt
    36421 ccgcgctgat gctcatcgtg ctgtcgctaa cggtctcctg tcgttatatc tggtggcgct
    36481 atacctcgac gctaaattgg gacgacccgg tcagtctggt gtgcggactg attctgctgt
    36541 ttgcggaaac ctacgcctgg attgtgctgg tgctggggta cttccaggtg gtgtggccgt
    36601 taaatcgtca accggtgccg ttgccgaaag agatgtcgca gtggccgacg gtggatattt
    36661 ttgtaccgac ctataacgaa gaccttaatg tggtcaaaaa taccatttac gcttcgcttg
    36721 gcattgactg gccgaaggac aagctgaata tctggatcct tgatgacggc gggcgcgaat
    36781 catttcgtca gtttgcccgg catgttggcg tgcattacat tgcccgcgct acgcatgaac
    36841 acgccaaagc cggcaacatc aacaatgcgt taaaacacgc gaaaggcgag tttgtggcga
    36901 tcttcgattg cgaccatgta ccgacgcgct cgtttctgca aatgacaatg ggctggttcc
    36961 tgaaagagaa acagctggcg atgatgcaga cgccgcatca tttcttctcc ccggacccgt
    37021 ttgagcgcaa cctgggacgt tttcgtaaaa cgcctaacga aggcacgctg ttttacggac
    37081 tggtgcagga cggtaacgat atgtgggatg ccactttctt ttgcggatcg tgcgcggtga
    37141 ttcgccgtaa gccgctggat gagattggcg gtatcgccgt tgagacggtg acggaagatg
    37201 cgcatacttc gctccggctg caccggcgag gttatacctc agcgtatatg cgcattccgc
    37261 agtcggcggg gctggcgacg gaaagcctgt cggcgcatat cgggcagcgt attcgttggg
    37321 cgcggggcat ggtgcaaatt ttccgcctcg ataaccctct gtttggtaaa ggcttaaaac
    37381 tggcgcagcg gctgtgctac ctcaacgcga tgttccattt cttgtccggc attccgcgcc
    37441 tgatctttct gaccgcgccg ctggcttttc tgctgctgca cgcctatatc atttatgcgc
    37501 ctgcgttgat gattgcgcta tttgtgatac cgcacatggt ccacgccagc ctgactaact
    37561 cgaagattca gggcaagtat cgtcactctt tctggagtga aatctatgaa acggtactgg
    37621 catggtatat cgcaccaccg actctggtcg cgttgatcaa tccgcacaaa gggaaattta
    37681 acgtcacggc gaaaggcgga ctggtggaag agaagtacgt cgactgggta atctcgcgtc
    37741 cgtatatctt ccttgtcttg cttaacctgc tcggcgtggc ggcgggcgta tggcgatact
    37801 attatgggcc ggaaaatgaa acgctgaccg tcatcgttag cctggtgtgg gtcttctata
    37861 acctggtcat tctcggcggc gcggttgcgg tttcggtaga gagtaaacag gtcaggcgcg
    37921 cgcatcgggt cgagattgcc atgccggggg ccatcgcccg cgaagatgga catttgttct
    37981 cctgtaccgt acatgacttc tccgacggcg ggttaggcat caagatcaac ggtcaggcgc
    38041 aggtgctgga agggcagaaa gtgaatctgt tgcttaaacg cgggcagcag gaatatgtct
    38101 ttccaacgca ggtagtgcgc gtaacgggca atgaggtcgg gctgcaactg atgccgctca
    38161 ccaccaaaca acatattgat tttgtgcagt gtaccttcgc tcgcgccgat acgtgggcgc
    38221 tttggcaaga tagcttcccg gaagataaac cgctggaaag cttgctggat attctgaagc
    38281 tgggcttccg cggatatcgc cacctcgcgg agttcgcgcc gccttcagta aaagtaattt
    38341 tccgatcgtt gacggcgtta attgcctgga ttgtatcgtt tattccgcgt cgcccggagc
    38401 ggcaagcggc gatacagccg tcggatcggg ttatggctca ggctcaacaa tgatgataat
    38461 gcgatgaaaa gaaaattgtc ctggatgtgt gcggcggtaa taggattaag cgcgtttcct
    38521 gctttcatga cggcggcggc gcctgcgatg ccgccattga tcaatgctga acccaccgag
    38581 cctgcgcagt cgcccgtaac tgaggcgccc gtcgtggcgc agaccgcgcc ttcgcgcgag
    38641 gtcaagctga cctttgcgca aatcgcgccg ccgccgggca gtatggcgct gcgtggcgtt
    38701 aaccctaacg gcggcattga atttggtatg cgcagcgatg aagtggcgtc gaaagcggtg
    38761 ttgaatctgg aatatacgcc ctcgccgtcg ctcctgccgg ttcagtcgca gctcaaggtt
    38821 tatctcaatg atgaactgat gggcgtactg ccggtgacaa aagagcagtt ggggaaaaag
    38881 acgctggcgc aggtacctat caatccgcta tttatcaccg actttaaccg ggggcggctg
    38941 gagtttgtcg gccactatcg cgacgtgtgt gaaaacccgg ccagcagtac tctgtggtta
    39001 gacatcgggc gaaatagcgc cctggatctg acctataaca tgctggcggt gaataacgat
    39061 ctgtcccact tcccggtgcc gtttttcgat ccgcgggata accgtccggt gacgttgccg
    39121 atagtgtttg ctgacatgcc ggatctggcg cagcagcagg cggcttctat tgtcgcgtcc
    39181 tggtttggct cgcgggcggg ctggcgcggt cagcgcttcc cggtgttgta taatcacctg
    39241 ccggatcgca atgcgatcgt gttcgccacc aacgatcgac gccccgattt cctgcgcgat
    39301 catcctgcgg ttaacgcgcc ggttatcgag atgatgaacc atccggataa tccgtatgtg
    39361 aagttgctgg tcgtgtttgg tcgagatgat aaagacctgt tgcaggcggc aaaaggtatc
    39421 gcgcaaggga atattctctt ccgtggttcc agcgtggtgg tcaacgatgt aaaaccgctg
    39481 ctggcgcgca aaccgtatga tgcgccgaac tgggtgcgta ccgatcgccc ggtcactttt
    39541 ggcgagctga aaacctatga agagcagctc cagtcgagtg ggctggagcc ggcgcccatc
    39601 aacgtttctt tgaatctgcc gccggacctc tatttgctgc gtagcaacgg tattgatatg
    39661 gatctcaact atcgttatac ctcgccgccg accaaagaca gttcgcggct ggatatcagt
    39721 ctgaataacc agttcttgca agcctttagc cttaacagca cgcaggaaac taatcgactc
    39781 ctgttgcgcc tgccggtact tcagggactg ctggatggta aaacggatgt gtctattccg
    39841 gcgctcaaac tgggggcgat gaaccaacta cgttttgatt tccgctacat gaatccgatg
    39901 ccgggcgggt cggtggacaa ctgtattact ttccagccag taccgaatca tgtggtgata
    39961 ggggatgact ccactatcga tttttcgaaa tattaccact ttatcgcgat gccggattta
    40021 cgcgcgttcg ccaatgcggg tttcccgttc agccggatgg ccgacctgtc tgacacgctg
    40081 gcggtgatgc cgaagacccc aaccgaagcg caaatggaaa cgctgctgaa tacggtcggc
    40141 gccattggcg ggcagaccgg tttcccggca attaatctga caatcaccga tgatagcgct
    40201 cagatagccg acaaagacgc cgatctgctg attattggcg ctattccggg caagctaaaa
    40261 gacgataagc gtatcgatct gttggtgcag gcgacacaaa gctgggtaaa aaccccgatg
    40321 cggcagaccg ctttcccgtc gattatgccg gatgaggccg atcgcgcggc ggatgcgcag
    40381 tccaccgtca ccgccagcgg cccgatggcg gcggtggtgg gcttccagtc gccgtttaat
    40441 gatcagcgca gcgtgattgc tctgctggct gacagcccgc gcggttacca gctactgaac
    40501 gacgccgtga acgacagcgg taaacgcgcc gcgatgtttg gttccgtggc ggtgatccgc
    40561 gagtccggcg ttcacagtct gcgcgttggc gatatctatt acgtcggaca tctgccgtgg
    40621 tttgagcggc tgtggtatgc gctggcgaat cacccggtgc tgctggcggt actggcggcc
    40681 ctcagtgtgg tattactggc gtgggtattg tggcgtctgc tacgtattct cagtcgccgt
    40741 cgtctcgacc ctgaccatga gtaacgcatg atgactatgc tgcgcggatg gataacgatg
    40801 atcgtcatgc tgacggcaat aaatgcgcag gcagcgtgta gctggcctgc gtgggaacag
    40861 ttcaagaaag attacattag ccagcaggga cgcgttatcg atccgggcga tgcgcgaaaa
    40921 attaccacct ccgaagggca gagctacgcc atgttctttg ccctggcggc gaacgatcga
    40981 ccggcgttcg cgcaactgtt taactggacg caaaacaatc tggcgcaggg atcgctgcgt
    41041 gaacatctgc ccgcctggct gtggggacaa aaagatcccg acacctggtc ggtgctggac
    41101 agcaactccg cgtccgacgg cgatatctgg atggcatggt cgctgctgga ggccggtcgc
    41161 ctgtggaaag agacgcgtta taccgaggtg ggcacggcgt tgctaaaacg catcgcccgc
    41221 gaagaggtcg tgaatgtgcc ggggctgggc tcaatgctgc tacctggcaa aatcggcttt
    41281 gccgaggcga atagctggcg ttttaaccca agctatctgc cgccgcagtt ggcgcaatac
    41341 tttagccgtt ttggcgcgcc gtggtcgacg ctacgggaaa ccaatttgcg gcttttgttg
    41401 gaaacctcgc cgaaaggttt ctcgccggac tgggtgcgtt atgaaagcaa gcaaggctgg
    41461 cagttgaaag cggaaaagac gctgatcagt agctacgatg cgattcgcgt ctatttatgg
    41521 acgggaatga tgcatgatgg cgatccgcaa aaagcgcgtt tactggcgcg atttaaaccg
    41581 atggcgacgt taacgatgaa aaacggcgtt ccaccggaga aagtggatgt cgtcagcggg
    41641 aatgcgcaag ggacggggcc ggtcgggttt tccgccgctt tactgccttt cctgcaaaat
    41701 cgcggcgccc aggccgtgca gcgacagcgg gtcgcagacc attttcctgg cagcgatgcc
    41761 tattacaact atgtgctgac tctctttgga caaggctggg atcagcaccg ttttcgcttc
    41821 accgtcaaag gtgaattatt acctgactgg ggccaggaat gcgtaagttc acgttaagtc
    41881 tcatgcacgc ttttttgctg gctggcggtc gaaatgcctt acctggcaaa aggggcgttt
    41941 ctcgggcatt gttggggtta tcgcttggta tggcgctaac accgcttgcc ggcgcagcga
    42001 cctccgcgca gcaacagttg ctggagcagg tgcggctggg cgaggccacg caccgtgagg
    42061 acttagtccg tcagtcgctc tatcgcctgg agctgatcga ccccaatgat ccacaggtta
    42121 tcgccgcccg tttccgctat ctgttgcgcc agggggatag cgacggggcg cagaagctac
    42181 ttgatcggct ggcgcaactg gcgccggagt cgacggcgta tcaatcttcc cgcaccgcga
    42241 tgctgctctc cacgccgcaa ggacgccagt ctttgcagga ggcgcgttta ctggcgacga
    42301 ccggtcatac tgaacaagcg atcgccagct acgacaagct gtttaaaggt tatccgccgg
    42361 agggcgaact ggcggtcgaa tactggacga ccgtggcgaa attgcccgcc cgccgtcacg
    42421 aagcgattaa ccagctacag aaaatcaatg ccgtcagtcc gggtaataac gctctgcaaa
    42481 atgcgctggc gcaactgttg ttcgccagcg ggcggcgcga tgagggattc gcggtgctaa
    42541 aacagatggc gaaatccagt acgggacgca gcgcggcctc cgccatctgg taccagcaga
    42601 taaaagatct cccggttagc gacgccagcg taaaagcgtt gcaagactat ctgacgcagt
    42661 ttagcgaagg cgatagcgtg tctgccgccc gcgcccagct tagcgagcag caaaaacagt
    42721 tagccgatcc ggcgtttcgc gcgcgctcgc agggcatcgc ggcggttaat gccggagaag
    42781 gcggcaacgc tattgcgcaa tcgcagcagg cggtgagcgc ccggcaggac gacagcgagg
    42841 cggtcggcgc gctggggcag gcatactcac agcgtggcga tcgcgcccgc gccgtcgcgc
    42901 agtttgaaaa ggcgctggcg atggcgccgc acagcagcag ccgcgataag tgggagagcc
    42961 tgctgaaggt caatcgctac tggctgttaa ttcagcaggg cgacgcggcc ttaaaagcga
    43021 ataatctggc tcaggcggag cgtttctatc agcaggcgcg agcagtggat aacaccgaca
    43081 gctacgcggt gctggggctg ggggatgtgg cgatggcgcg caaagataat gccgccgccg
    43141 aacgttatta tcagcagacg ctgcgtatgg acagcggtaa taccaatgct gtacgcgggc
    43201 tggcgaatct ttatcgttag cagtcgccgc aaaaagccgc cgcgtttatc gcttctcttt
    43261 ccgccagcca gcggcgcagt atcgacgata tcgaacgcag tctggaaaat gaccgtctgg
    43321 cgcagcaggc ggaaacgctg gaaagcgagg gcaaatgggc gcaggccgca gaactgcacc
    43381 gccgccggct ggcattagat ccggggagcg tgtgggtaac gtatcgactg tcacgcgatc
    43441 tgtggcaggc cggacagcac gcccaggccg atgcgcaaat gcgctctctg gcgcagcaga
    43501 agccaaacga tccggaacag gtctatgctt atgggcttta tctttccggc agcgatcggg
    43561 gccgggcggc gctggcgcat ctcaataccc tgccgaccag ccagtggaac agcaatattc
    43621 aggaactggc gggccgattg taaagtaacc aggtgctgga aagcgctaac cgcttgcgcg
    43681 atagcggcaa agaacgcgaa gcggaagcgt tgttacgtca gcagccgccc tctacgcgca
    43741 ttgcgttaac gttggcggac tgggcgcagc agcgtggcga taatgcggcg gcccgcgccg
    43801 cttatgacgc cgttctggcg cgggaaccgg gtaatgtcga tgccatgctg gggcgggtgg
    43861 aaatcgacat cgcacagggc gataacgctg cggcgcgcgc tcaactggcg gcgctgcctg
    43921 cgtcgcaaat cacctctatt aacatgcagc gccgcgtcgc gctggcgcag ctccagcttg
    43981 gcgatatcac ggcggcggcg cggatcttta accgcattac gccgcaggca aaagcacagc
    44041 cgccatcaat ggaaagcgcg atggtattgc gtgacgccgc cgcttttcag gcgcaaacgg
    44101 gcgagccgca gcgggcgctg gagacctaca aagaggcaat ggtcgccgcg gcgattacgc
    44161 cggttcgccc ccaggataac gataccttta cccgcctgac gcgcaatgat gaaaaagatg
    44221 actggctaaa acgcggcgtg cgtagcgatg cggcggagtt gtaccgtcag caggatctca
    44281 atgtcacgtt ggcgcacgat tattgggggt cgagcgggac tggcggctac tccgatctga
    44341 aggcgcatac cacgatgctt caggtggatg cgccctggtc ggacggacgg gcgttctttc
    44401 gtactgatat ggtgaatatg gatgttggtc gcttctctac ggatgcagat gggaaatacg
    44461 ataataactg gggtacctgt acgctggaga aatgcagcgg acatcgtagc caggccgata
    44521 cgggcgcgag cgtggcggtc ggctggcaga atgagacctg gcgctgggat atcggcacga
    44581 cgccgatggg ctttaatgtc gttgatgtgg tcggcggcgt cagctatagc gacgatatcg
    44641 ggccgttggg ttataccctg aacgcgcatc gtcgcccgat ctccagctcg ctgctggcgt
    44701 ttggcgggca aaaggacgcc agcagcaata ccggcaccaa atggggcggc gtgcgggcca
    44761 acggcggcgg cgtcagtctc agctatgata aaggcgaagc aaacggtgtc tgggcgtcgc
    44821 tcagcggcga ccagttgagc ggtaaaaatg tggaagataa ctggcgcgtg cgctggatga
    44881 ccggttatta ctataaggtg attaacgaga ataaccgccg cgttaccgtc gggctgaata
    44941 acatgatctg gcattacgac aaagatctga gcggttattc actgggtcag ggcggttatt
    45001 atagcccgca ggaatacctg tcgtttgcgg tgccggtgat gtggcggcag cgtacggaaa
    45061 actggtcgtg ggagttaggc ggctcggtat cctggtcgca ctcccggcaa ccgtaccatg
    45121 ccgcgttatc cgctgatgaa tttgattccg gcggattatc aggaggatgc gcgtgaccag
    45181 accaacggcg gcggcagcag tcagggattt ggctataccg cgcgggcgct cattgaacgc
    45241 cgggtcactg ccaactggtt tgtgggtacg gctgtcgata tttagcaggc gaaagattat
    45301 acccccagtc atctgctgct gtatgtccgt tattccgcgg caggctggca gggggatatg
    45361 gatttaccgc cgcagcctct ggtgccttac gctgactggt aatcattgcg tcaggcctac
    45421 gtattgacag gcgtcgtagg cctgagaagc gcagcgccat cagacgctat cattaaccgt
    45481 tattcagaaa agtccttttc agatacagcc tctcttaatg ccgctgcaat cgggtatact
    45541 caggcggcag tccgggatat ccagggagag tcaatttgcg cgtcagccgc tcgttaacaa
    45601 ttaaacagat ggcaatggtt gcggccgttg tcatggtgtt tgtttttgtc ttttgcaccg
    45661 ttttgttgtt ccatctggta cagcagaacc gctacaacac ggctacgcaa ctggaaagca
    45721 tcgcgcgctc tgttcgggaa cctctttctt ccgcgatttt aaaagcggat ctccccggcg
    45781 cggaaaccat tctggaaagt attaaacctg cgggcgtggt gagtcgcgcc gatgtggtat
    45841 tgccgaatca gttccaggcg ttgcgtaagc gcttcattcc tgaacgcccc gtcccggtta
    45901 tggtgacgcg tctcttcgaa ctgccggtac aaatttcttt gccggtttat tcgctggagc
    45961 gtcccgccaa tccgcaaccg ctggcctacc ttgtattgca ggcggattcg taccgtatgt
    46021 acaagttcgt catgagcgcg ctctctacgt tagtgaccat ttacttactt ttatcgctga
    46081 tcctgacggt ggccatcgcc tggtgcgtaa accgcctgat tgtgcatccg ctgcgcaaaa
    46141 tcgcccgcga gctgaacgac attccgcagc aggagctgat cggacatcag ctggcgttgc
    46201 cgcgtctgca tcaggatgat gaaattggga tgctggtgcg cagctataac ctcaaccagc
    46261 agcttatgca gcgtcaacgc gaggagcaaa cggacaacgc gatgcgtttt ccggtttccg
    46321 agttgcccaa taaagccttt ttaatggcgc tgctggaaca ggttatcacc cgccaacaga
    46381 ccaccgcgct tatcatcgtg acgtgcgaaa cgttgcgtga cacggcaggc gtgctgcaag
    46441 aaacgcagcg ggagattcta ttactgacgc tggttgagaa gctgaagtcg gtgctggcgc
    46501 cgcgcatggt gcttacgcag gtcagcgggt atgactttgc cattatcgcc cacggcgtca
    46561 aagagccgtg gcacgccatc acattaggtc agcaaatact cactatcatt aatgaacgac
    46621 tgcccatcca gggtattcaa ctgcgcccaa gctgcagtat tggcattgcg atgtattatg
    46681 gcgatctgac cgccgaagcg ctctatggtc gcgccgtctc cgccgcgttt accgcgcgcc
    46741 gaaaaggtaa aaatcagatc cagttctttg acccggcgca gatggaggcc gctcaacagc
    46801 gccttaccga agagagcgat atccttaccg cgctggataa ccatcagttt gccatttggc
    46861 tgcagccgca ggtcgagatg cgcagcggca acgtattaag cgccgaagcc ttgttacgta
    46921 tgcagcagcc ggacggtagc tgggaattgc cggaggggct gattgagcgc attgaatcct
    46981 gcggcctgat ggtcacggtg ggccattggg tgctggaaga gtcctgccgc cagcttgccg
    47041 cctggcagga gcgcggcgtg acattgccgc tctccgtcaa tctttccgcg ttacagctca
    47101 tgcaccctgg catggtgtcg gatctgctgg aattgttaaa ccgctatcgt attcaaccgg
    47161 gtacgctgat tcttgaggtc actgaaagcc gccgtatcga cgatccgcac gctgccgtcg
    47221 ctatcttacg tccgttacgt aatgctggcg tgcgtatcgc actggatgat tttggcatgg
    47281 gttacgcggg gctgcgccag ttacagcata tgaagtcgct accggtcgat atccttaaaa
    47341 ttgataaaat gtttgtcgat gggttaccgg atgatcacag tatggtgacg gcgattatcc
    47401 tgatggcccg cagtcttaat ttacaattga ttgccgaggg cgtggaggac gaggcgcaac
    47461 gcgcgtggct ggaacaggcg ggagtcaacg tcgcgcaagg cttcctgttt gctcggcccg
    47521 ttcccgcgga tatctttgaa gaacggtatc tgtcgcacga aaatcctgat tacaaaagtt
    47581 aaaaaaggtc gcgcttgtgc gagtcagctc aaacttttta acatttttgt ttcaattatg
    47641 atcctggcgc atttctgtca tgttgtgtgg gtgttatttt aaggccgcag gttactcata
    47701 accttacaag acctgtggtt tttacttcaa ggacacccta tgaaaacctc tctgttcaaa
    47761 agtctttatt ttcaggtcct gacagcaatc gccattggta ttctccttgg ccattactat
    47821 cctgaactgg gcgcacaaat gaaaccgctt ggcgacgcgt tcgttaagct cattaagatg
    47881 atcatcgctc ctgtcatttt ctgtactgtc gtgacgggca tcgcaggcat ggaaagcatg
    47941 aaagcggtgg ggcgtaccgg cgcggtcgcg ctgctttact ttgaaattgt cagtacgatt
    48001 gcgctgatta acggtcttat catcgtcaac gttgtgcaac ctggcgccgg gatgaacgtc
    48061 gatccggcaa cgctggatgc gcaggcggtg gccgtttatg ccgcacaagc caaggagcag
    48121 ggcattattg ccttcctgat ggatgtcata ccgggcagcg tgatcggcgc gtttgccagc
    48181 ggcaacattc tgcaggtctt actgtttgcg gtgttgtttg gttttgcgct gcaccgtttg
    48241 ggcagcaaag gccagctcat tttcaatgtg attgagagtt tttcgcaggt cattttcggc
    48301 atcatcaata tgatcatgcg cctggcgccg attggcgcat tcggcgcgat ggccttcacc
    48361 atcggtaaat acggcgtcgg ttctctggtg caactggggc agctcattat ctgcttctat
    48421 atcacctgta ttctcttcgt ggtggtggtg ctggggacga ttgcacgggt aacgggcttt
    48481 agcattttta aatttattcg ctatatccgg gaagaattac tcattgtgct cggcacctcc
    48541 tcttccgagt cagcgttgcc gcgtatgctc gataagatgg aaaaactggg gtgccgtaaa
    48601 tcggtggtgg ggctggtgat cccgacgggg tattcgttca accttgatgg cacctctatc
    48661 tacctgacga tggcggcggt gtttatcgcc caggcgacca acagccatat ggatatcttc
    48721 caccagatca cgttgctggt cgtgctgctg ctatcgtcaa aaggcgccgc gggcgtgacc
    48781 ggaagcggct ttatcgtgct ggcggccact atctccgccg taggtcattt gccggtggcg
    48841 ggactggcgt taatcctcgg tatcgaccgc tttatgtccg aagcgcgcgc gctgactaac
    48901 ctggtgggta acggcgtggc gacggtggtg gttgccaaat gggtgaaaga gttagatcac
    48961 caaaagctgg acgatgtgct taataatcgt gcgccggatg gcaaaacgca cgaaatttcc
    49021 tcctaatctc gccacttatg cccgtagtcc cttccaggac tgcgggtgtt tgcgcataat
    49081 tgacccctgc gcccaaagca tacagcatga tgcttaggga ttatttcact tcttccgtga
    49141 catttttagg ttctcgcggt ctaacacgaa gtgtttttac gtcatattca ggcatccctg
    49201 ccggggctgt ctttttatta ccaggattgt tgatcagggg ttcacatgca gggcacaaaa
    49261 attcgactct tagcgggcag tctgttgatg ttggcctctg ccggctatgt gcaggcagat
    49321 gcgctccagc ccgatccggc atggcaacag gggacgctgg ctaatgggtt acagtggcaa
    49381 gtgttggcta cgcctcagcg ccccagcgat cgtattgaag ttcgtctaca ggttaatacc
    49441 ggttcgctca ccgaaagtac gcaacagagc gggtttagcc atgcgattcc ccgtatcgcg
    49501 ctgacgcaaa gcggtggtct ggatgccgca caggcacgtt ctttatggca gcaaggattt
    49561 gatccgaaac gtcccatgcc gcccgttatt gtttcttatg attccacgct ctatagcctc
    49621 agtttaccca ataaccgtaa cgatctgctg aaagaagcgc tgacctatct ggctaacgtc
    49681 tccggtaaat taaccattac gccagagacg gtgaatcatg cgttaagcag cgaagatatg
    49741 gttgcgacgt ggccagcaga tactaaagag ggctggtggc gttatcggct gaaaggatcg
    49801 gcgttattgg ggcacgatcc cgcggaaccg ttaaagcagc cggtagacgc agccaaaatt
    49861 caggctttct atgaaaaatg gtacaccccg gatgccatga cgctgattgt tgtcggcaac
    49921 attgatgcgc gctccgtcgc cgagcagatc aataaaacgt tcggtacgct gaaaggtaaa
    49981 cgcgaaacgc ccgccccggt gccgacgctt tcgccgctgc gggcggaatc agtgagcatt
    50041 atgaccgatg cggtgcgcca ggatcgtctc tccattatgt gggatacgcc gtggcaaccg
    50101 attcgcgagt cggcggcgct gttgcgctac tggcaggcgg atctggcgcg cgaagcgctg
    50161 ttctggcata tccagcaaga gcttactaaa aataacgcga aagatattgg tctggggttt
    50221 gactgccggg ttctgttcct gcgcgcgcag tgcgccatca acattgaatc acctaatgat
    50281 aagctcaata ccaatttgag cctggtggcg aatgaactgg cgaaagtacg cgataaaggt
    50341 ttgtcggaag aggagtttac tgcgctggtg gcgcagaaaa atctcgaatt gcaaaagcta
    50401 ttcgcgacct acgcgcgtac cgatactgac attttgactg gacagcgtat gcgctcgctg
    50461 cagaatcagg tggtggatat cgcgccggag cagtatcaga agctgcgtca gaatttcctc
    50521 aacagcctga ccgtcgatat gctcaatcag aatctacgtc agcagctatc gcaggagatg
    50581 gcattaattt tgctgcaacc gcaaggcgag ccggaattta atatgaaggc gttaaaggcg
    50641 acgtgggatg aaatcatggt tccggcaact gccgccgctg ttgaagcaga tgaggcgcat
    50701 ccggaagtga cggaaacacc ggcggcacag taagcggccg cctgtcggcc cggtaagcgc
    50761 agcgccaccg ggcaagaacg aatgacttac tgcggcatcg cgtcgtgcgg aataatggcc
    50821 ccacggtact gaatcaccgt gctggccgtc aggtgtccgc gcttcgcggc atccgtcgcg
    50881 ctgccgcccg tcaaacgaac ggccagataa ccggcgctga aggagtcgcc tgcggcagtg
    50941 gtgtctatca ctttctcttt cggcagtttt actgccggaa cgtcaatgag cgcctcgccc
    51001 tgaatcgaga ccaggcaaga gtccgccccg cgttttacca ccacttcctg tacgcctgcc
    51061 gcatgggtgc gagcaatgac ctcttccacc ggttgcttac cccatagcgc gtcttcatcg
    51121 tccagtgtca ggaaggcgat atcagtacat tccagcatct tttgatagac ctgctgcgtt
    51181 tcttcgcgac ttgtccataa acgcgggcga tagttattat caaaaatgac tttcccgccg
    51241 ttggcccggc attcacgcaa taaagacagc agcttatcac ggctggtcgg gcttaaaatc
    51301 gcgaggctaa tgccgctcag gtagagataa tcgaaggtcg ccagcgtctc gcagatagcc
    51361 gctgactgct cgctctccag ccagaatttc gctgccgctt cgttacgcca gtagtagaag
    51421 gtacgctcgc cagtgtcatc ggtttcgatg taatagaggc ctggcaggcg attttccatc
    51481 cgctgcgtta gcgaggtatc cacattttca tgctgccacg cctccagcat ctgttggctg
    51541 aaactgtcgg tacccagcgc cgttacatag tgaacggcca gagcggcaga atcgacctga
    51601 cgggcaatat aaacggaggt attcagcgtg tcgccgccga agccgcgctg aacatcagcg
    51661 cctttctgcg acagctcaat catgcattcg ccaatcacgg caatcttttt agacatagtc
    51721 gtgaacctga tctgtaaaaa ttagcgttag tgtgcgctgt ggatgtttag cggtcaataa
    51781 tattaaaaca tcggtccatt atttttttga gcaagtgcgt atttttgaca agtttcgtgg
    51841 tctgttttta ttttgccagg gaccgagggt aaagttctct gcctgaacgc cgataacctt
    51901 tgacgagtcc ggactgtcac actcccatta acaggacaac tgagatgata aagcaggtta
    51961 tccagcagct acgcgttcct gatgcaggta tagagaattt gcaggaacgg cgctattggc
    52021 tgcaatgcga gcgtgcctat acttaccagc cgatatacca gacggatggc cgtctgatga
    52081 cggttgaact tctcactgcc gtcacccatc ctgataaccc ttccagacgt attgccccgg
    52141 atcgttattt cgcggaatta gcggttcgac accgcattga cgtagtaaaa gaacaacttc
    52201 atcagcttga acaaaaagcg gattttttca ctcgccatcg cttattggca tcagtcaatg
    52261 tcgacggccc tacgctgatt gccatgcgac aacagccgga cattctggca gcgatggagc
    52321 gcttaccctg gctgcgtttt gaactggtgg aacatattcg tttgccgaaa gactcctctt
    52381 tcgcctcgat gtgtgagttc gtcccgctgt ggctggatga ttttggtact ggtatggcca
    52441 atttttcagc gctgagcgaa gtgcgttatg actacattaa agtggcgcgc gagctgttcg
    52501 tcatgctgcg ccagtccccg gaggggcgca acctgttcat tctgctgctg caactgatga
    52561 accgctactg ccgcggcgtt attgtcgaag gcgtggagac tctggaagag tggcgtgatg
    52621 tgcagcgttc gcccgccttt gccgcccagg gctattttct ttctcgaccc gtgccgctga
    52681 tatcgctcga agaggtgatt ctgaccctgt aacgccagac tgttcccgta atacgtggta
    52741 ttacgaggtg cggtcatcct cctttttcgt ctggctgaac tatctttagg acaggcaagg
    52801 gaagaagtga ggaaataaca catgactaaa gcaggcaaaa taaccgccgc catcacaggg
    52861 actttcttgt tgttgatcgc catagtgatt ttgttgatcg caacatttga ctggaaccgc
    52921 ctcaaaccga ccatcaacca gaaagtctct accgaattga accggccttt cgctattcgc
    52981 ggcgatttag gcgtggtgtg ggaacgccaa aaacaggagt ccggctggcg aagctgggta
    53041 ccgtggccgc atgttcacgc ggaagacgtc attctcggca atccgccgga tattccggaa
    53101 gtcacgatgg tgcatctgcc acgcgttgag gcgacgcttg ccccgctggc gctcctgacc
    53161 aaaaccgtct ggctgccgtg gatcaaactg gtgaaacccg acgcgcgtct tattcgtctg
    53221 tccgagaaaa ccaataactg gacctttaac ctcgcgcaag acaagaatac ggaccccaat
    53281 gctaaacctt ccgcctggtc cttccggctg gataatattc tcttcgacca ggggcgaatc
    53341 gcgatcgatg ataaggtcag taaagcggat atcactattc tggtcgatcc gttaggcaaa
    53401 ccgttgccgt tcagcgaagt gacgggaacg aaaggcaaag cagacaaatc caccgtgggc
    53461 gactatgtct tcggcctgaa ggcgcagggg cgttataacg gggaaccgtt gaccggtacg
    53521 ggcaaaatag gcggtatgct ggcgctacgt agcgaaagta cgccttttcc tgtgcaggcc
    53581 gatttccgct ctggcaatac gcgggtggct tttagcggcg tggtgaacga gccgatgaaa
    53641 atgggcggcg tcgatctgcg gcttaaattc tctggcgatt cactgggcga tttatatgat
    53701 ttaaccggcg tgctgctgcc ggatacgccg ccgtttgaga ccgatgggcg attggtagcg
    53761 aaaattgacg ccgaaaagtc atcggtattt aattatcgcg gttttaacgg gcgcattggc
    53821 gacagtgata tccacggcac cttcacttat accaccggta aaccgagccc caaactggaa
    53881 ggcgatgtcg aatcgcgcca gttacgcctg gccgatcttg ggccgctgat tggcgtggat
    53941 tccgggaaag acgctgagca gtcgaaacgg tctgaacagc gcaaaggcga gaagaatgtt
    54001 cagccggcgg ataaagtgtt gccttacgat cgctttgaaa ccgacaaatg ggacgtcatg
    54061 gacgccgatg tccggtttaa aggccggcgt attgagcatg gcggcagtct accgattagc
    54121 gatctttcga cccatatcat cctgaaaaac gccgacttac gtctacagcc gctgaagttt
    54181 ggtctggcag gcggcagtat tgtctccaac atccatctgg aaggggataa aaagccgatg
    54241 caggggcggg cggatataca ggcgcgtcgg ctgaagctta aagaactgat gccggatgtg
    54301 gagctgatgc agaaaacgct gggcgagctg aacggcgatg cggatattcg cggcacgggc
    54361 aattcggtcg ccgcgctgct tggcaacagt aacggcaatc tcaaattatt gatgaatgat
    54421 ggattgatta gccgcaacct gatggaaatc gtggggctga acgtcggcaa ctatattatc
    54481 gggcagattt ttggcgatga cgaagtgcgg gttaactgcg cggcggcgaa tctcaatatt
    54541 gcgaacggcg tggcgcgacc gcaaattttt gcttttgata cagaaaatgc gttgattaac
    54601 gtgaccggta cggcgagctt cgcctctgaa cagctcgatt taaccattga tccggaaagt
    54661 aaggggattc gtattattac gctgcgatcg ccgctttacg tgcgcgggac atttaaaaat
    54721 ccgcaggcgg gcgtcaagcc cggcccgctg attgcgcgcg gcgcggttgc ggcagcgctg
    54781 gcgacgttgg taacgcccgc cgccgcgcta ttagcgctca tttcgccctc tgagggcgaa
    54841 gccaatcagt gccggacgat tttaacgcag atgaagcagt aacgtgaaac gtcgcgccgg
    54901 atgacgccat ccggcgccct attacaacgc ctgatgacgc gtctcatggg ttaacagcag
    54961 tgcaatcagc gtcagcgccg ccattgacgc caggtaaacc cctaccgccg ccagcccgta
    55021 gtggctttgc agccatgcgg caatatacgg cgcgacggaa gcgcccagaa tcgatgacac
    55081 attgtaggaa aacgatgcgc cggtatagcg tacttccgtc ggaaatagct ccggcagcag
    55141 cgctcccatt gggccgaagg tcagccccat caggctcaga cctaacaaca ggaacacgaa
    55201 taccagcgct ggattgcctg aacccagcag cggggtaaag gcgaacaacg cgaagagaat
    55261 gatgagcgtg gtaatgatga ccatgctttt ccgacggcca aatgcgtccg ccagcaggcc
    55321 ggcgacgggc accatcacgc cgaaaccaat caccgccatc atcagcatcc acagtatttc
    55381 attgcgcggc aagccaagcc ccaccggcgc ggcggcagtg ctgtaagtca tggaatagac
    55441 ggtcatgata tagaacagcg tgtaggtcgc cagcatgata aacgtgccga gaatggttac
    55501 gtggacatgc ttcgtcagca acgtgcccag cggtattttt acctgctttt tcgctgcggc
    55561 gactttcgca aacaccggcg tttcatgcag cgacacgcgc acatacaggc cgataatcac
    55621 cagtaccgcc gagaagataa acggcacgcg ccagccccag ctcataaatt gctcgtcggt
    55681 cagtagccag gagagcaacg ggaaggtgcc attggcaaaa aagaagccga tcggcgcgcc
    55741 caactgcggg aaggagccat acagcgcgcg tttgcgcggc ggcgcattct ccgtcgctaa
    55801 taacgctgcg ccgccccatt cgccgcccag ccccagtccc tgaccgaaac gcgccagcgc
    55861 cagcagcagc ggcgcgaaaa tacctatcgt cgcgtagccc ggtaacagac cgataatgac
    55921 cgtggagatc cccatcgtca gcagcgaagc caccagcgtg actttgcggc ctacccggtc
    55981 gccgaagtga ccaaatagcg cagagccgat cggacgcgcc acaaacgcga tagcgaaggt
    56041 ggcgagcgat tgtagcgttg ccgcagtggg atcgccctgg gggaagaaga taagggggaa
    56101 cacgatcacc gctgcggtgg cgtaaatata gaagtcgaag aactcaatcg cggtgccgat
    56161 aagcgaggca ataacgactt tattgcgtga gtttaccgga acatgttcct gctcatggtc
    56221 gagtgttgtg gcggttgctt gcatactatt ttcttatttt tagcgaacga atagccatat
    56281 tacgcacagc aaaagttata tttcaatgtg taacaaaagc caaaaatggt caaaaaaagc
    56341 gcaaaaaggg gataatgttt aagccagcta ttttgcgtct atgaaatgct tcacataatt
    56401 ttaggattgg tggataaaac tggtttctgg ttaaataaaa gttaattacc ggattgatat
    56461 gctgaaacaa tgagatgagg cggaaggacg tgcctgattg taccgccggg tacgctttac
    56521 atacctggcc tgggtccata cagcagtagg ccgaatgacg acgccgtgcg tgccattcgg
    56581 cagcaagccg cagactagcg ttgcgtttta cccggcattc gcgggtcgtc cttatattcg
    56641 gcggtggcta tccaggccgc gcagaataac gtcaggcggg caaaaaagta gaagaatgcc
    56701 atcagaccga gtacggagcc aaacgccgcg ccggaaggcg atttcaccag tgacggcagc
    56761 gtataagtca taatgatttt aatcacctca aaaccgatag cggcgataaa tgtcccgcga
    56821 atcaacgctt ttttacgggg acgatggcga ggcagtcgcc agaaaatcca gaagaaaagc
    56881 agatagttgg caaaaataga gatggccaga ccgatcaaat gccaggccgg ttttaaccat
    56941 tcgatgctgt cgagatacaa ggcggagatg atcatctgct gggcggaacc ggcgatggaa
    57001 gtaatggaca gcgtaatgat taaagcgatt aataatccaa tcagcgagat aaaatcgcgc
    57061 agatatttga gccagatttt ctcctgatcc tgcggcttgc gctcccagac gtcccgtgac
    57121 tgggcgcgaa tcgcttcccg caggttgccc atccagttaa cgccggaata gagcgcgata
    57181 cccagtccga ccagccctac cgtggtacgc tgttgaaccg ccgtattaat cgtattttta
    57241 agcgtggacg ccagcgtagg atcgctcaca ttcatcaata tcttgctgaa aatatcttcc
    57301 agtagattag ggtgcgaggc gaggataaaa cctgccgcgg caaaggacac catcattatc
    57361 gggatcatcg acagaaacga aaagtaggtg atagccgcgc caaactgatt acccagtcga
    57421 tcgttaaaac gttcggtcgc gcgaatgagg tgggccacca tcggttgacg ctgtattttt
    57481 tgcatcaggg tggtgacgga atgcaacgcc tgatttgcct tttcgttttt ttccggggcg
    57541 tcatgcggct gcgtttctat tttttgtatc gggtcgtgct ccagttcctg aatagggcgt
    57601 tttacgtcat tttcctgcgt catcaggtcg gtagtccttc atcattaata gaatatgtca
    57661 gtatagcttc tccccggtgg atgctgaaaa tgcggctact ctgcggcctc tttaatggtt
    57721 tcagtcagcc ataccataaa caggtgtacc cggcgggaaa gattacggcg atggggataa
    57781 tgcagcgtca ccggcagtgg agcggcgcga tattgcggta aaatttcaat gagcgctccg
    57841 gcgcgtaacg cctcccgtac agcaatgcgc ggcgtctgaa tgatccctaa tcctgccaga
    57901 caggccgtat gccaggtctc cgtactgttt accgttagca ttccgccggt ttttacccac
    57961 tgcataccgt ggggagtttc gaaggcaaaa cccggtgaag agactcccgg ggtcaatgaa
    58021 taatgcacca tcgcatgtga ggcgaggtcg tcaaggtttt ctggatatcc aaagcgcgcc
    58081 aggtattgtg ggctggcgca gttcaccctt cttagtttgc caagcgggcg cgtcagtatc
    58141 cctggcgcat gtagcggctc tgtgcgcacc acacagtcga aatcttcccg tagtaaatcg
    58201 acctgtcgat cgctactaca aagttccagc gcaatgccgg gatactgatg caaaaaagtg
    58261 agcaggcgcg gcatgataag gctgtttgcg agacctggcg ggatatctac ccgtattttg
    58321 ccgctgatac tggcgggatc aggctggaaa agaccctcca gttcatccag gttactcaac
    58381 agatcttttg cccgttcgta gtaaaccatc ccgtcctgag taagctgtac ccgccgggtg
    58441 gtgcggtgga gcaggcggat gcccagttga tgttctaacg cttgtatttg ccgtgagacg
    58501 ctgcctttgg gaaggccgat atcttctgct gcgcgggaaa aactttcccg ttccgccacg
    58561 cgcacaaaca atttcattgc atatatttta tccatcatca ggctctatta ttgtttttat
    58621 tgaaacagtg acgctgaagc ggctggtttt attgattttc tagcatctaa taagcccttt
    58681 cgcaatcatt gctcgcgtga cgaatacgtc tgatcgcgtt gcgcggcgga tttatcgcct
    58741 tccggctagg cattttagcg ccaaaaagcc gataaacggg acgagagcgg taaaacacgc
    58801 tgatagccgc gggtgtagtg ggagagagaa atgcatgtac atatacggta ttgtcattga
    58861 cccatcgtcg cggttttcag gcggattggc tattttttaa caaaatgtgc tactttattt
    58921 tttgtaacac ataaggcgaa aagcagatat ttcctttgtg acgcgccagg cgtactcttc
    58981 attaaattaa tattcaaatt agccctgtct gtttgtacta ataagatatt ccttacttta
    59041 aaacgctaat gttagcgaat tctgtaatcc cgatgttgaa gctgtaaata ttcataacct
    59101 ttctcttcct caaccaatga ctatcggtaa aatggcctat accaaatggc gacttcttat
    59161 tttaccctac gggtaatacc cttcctcatc ttgagactat tatcttaccc aggtggagaa
    59221 aagtaatgca ggtaatcatg tttgacaggc agtcaatatt tattcatgga atgaaaatca
    59281 gtttgcagca gcacattcca ggaataagta tccagagtgt cggtcaggca gaagaactct
    59341 ggcaaaaaat agaaagcgcg ccggatgcgc tggtcatgct ggatagcggc ctggatgctg
    59401 aattttgccg cgaggtgtta caaagaaccg cgcagcaatt tccggaggtg aagattatta
    59461 tcacggcgat ggatggcagt caaaagtggc tgcatgaagt catgcaattt aacgttcagg
    59521 tcgtggtgcc acgcgattct gatgccgaaa cctttgtcct tgcgctcaat actgtcgctc
    59581 gcgggatgat gtttttaccg ggggattggt taaattcaac ggagctggag tcccatgata
    59641 taaaagcgtt aagcgcccgc cagcgggaaa ttttacagat gcttgccgca ggagaatcaa
    59701 ataaacaaat tgggcgggcg ttaaatatta gtaccgggac ggttaaagcg catctggagt
    59761 cgctttaccg gcggctggat gtaaaaaatc gtacccaggc cgccatgatg ttaaatgaat
    59821 cgaattaacg acgttaaatt cgcagtccgc ttatttctgg ctgtgaaata tcatccgtat
    59881 tgattaatga taaaaaacgc tgatgtccga tgctgaacat cagcgcaata agcgtttcgc
    59941 gttgaaaccg atcgttaagt tccggcaagc aattctgtag cagcatatcg cagctattga
    60001 ggtcatccag caagaatgcc tccgcctggt cgggcgtaat gaacgtcagc gtctcatccg
    60061 gcgtcaacat atgcccgtaa ccaatcaccc agttaccctg ccgatcgcga tacttttcca
    60121 gcgacagacc ctgccactgt ttaataaacg cgatgcaggc ggagctaaag cgagatgaaa
    60181 tgtgcggcat ggcatctttc tcataaaaag cgcgattata aagtgtgctg cacgcgtggc
    60241 tagcggtcag acggccaaac gcaggcaggg aaaaggtcta tgccgttcag cgtcacgccg
    60301 cgttgacaga atgaaaaact gatgtttttg gttagtaacc gatcttctta taaatttgca
    60361 atcattaaga ttaagtcact gaaatgtggc taaatctgtt atatctatga aaaaacataa
    60421 ttaaaagaaa acgaagatct cgtcgcggga tcgtcttttt agggaagata atgacgaata
    60481 gcgcttcgca ggcgacacgc gcgccttttg aacatagcct ggggattatc cgccaggcat
    60541 caatagaaat cctgctgctg ctgggtattc ataccacaga gggaaaagag ccccggtggt
    60601 tcatggaaca acttgagcag gcgcgtctta acctgggcgg ttggggcgcg gtggcgaaaa
    60661 aattgcggat aaatgacgcg cagttgagcc agtttatgct gcaactgcgt catcttcagc
    60721 agcatgttcc ccagtatgac agcgggcaag aggtgagcga aaatcaactc cttgccgcgt
    60781 tgcgttttgt cacctcgctg gaacatctac gtcagcagca gccgctactg acgtatcaaa
    60841 ctgagctgga agaccccgac caggaggcgc atcttgaggc gcagcgtcag cttcgggcga
    60901 tagaactgac gttaaaagcg cttattgcgc gcgcatggcc ggatcgggcg tccctgaatc
    60961 actacctcaa gcaacatttt ggcccggacc gtttgcgcca gtggttaaaa cagggagaag
    61021 atcaacatgc gctggagggc atgttgttta gcgaactggc gcttatggtg gtcgataaaa
    61081 aattgtttgc tcgtcattac gtcagaattt ttaatgacgc ctcagcgtta acgctgttcg
    61141 ccgagtcgcg caccactctg cgtatgtttc tggatgattg ccgcctcgcg cgaaacgagg
    61201 ttatcgccag gcagccgctc acctcagcgc agcttatgct gctaaacgtt cagtatcagc
    61261 aaatcgttcg gcccatccag cgcgcctatg ccgaaaaacg tacccgcgtg aatcccgctt
    61321 cgtttctgct ggcggatgaa cgtgaattgc gccagttctg ggaaaccgcg cggcttaaag
    61381 atcggcaggc cgggggagat aagcatgaga ttagcgagag catagaacca ccgcgtaagc
    61441 ggcctccgcg tacgcctgaa gagcgtgagc aacttatttc cggcgctttg tggggcgggg
    61501 ttggcgtcat gacgctggcg atactggcgg gcgcgttctg gctatttagt tcgtcatcgc
    61561 caagctccga taacgggcaa gctcccgcaa tggcgcagga tgaaccgccg cgcgaggcgc
    61621 cttccgcgcg ggaaacgctc aatcatatgg ggattacctg ggatgcgttt accatgcggg
    61681 cggcgataga gcgcaatgat acgcgggtga cggcgctgtt cctccagggc ggaatgaact
    61741 ggcagctcgc gtggacggag caggcgtttg cggcaggaca taccgaggtg ctgcaactgt
    61801 tgttgcgtta tcccgcgctg atggatgagg tcaaaccctg ccgacgattt atcacaacgt
    61861 taagtcatga catgtcgagc ggcgcgccgc tgaccgcgat gcataaaacc tatttgcaaa
    61921 cgttttgcac cgttccggct gttgtgacgc gccagcagta cgatacggag caggcccagc
    61981 tgcgcgctca ggcccggccc agcgcagaca ataaaaaatg gctgaaaatt cagtcagcca
    62041 tttatgatgc gattcactga gcccggagca ggttaaggct ctccgtaaag gccaatcagg
    62101 cggcgcacca cgccattggt ccagccgaac ccatcctgta gcggatactc gcccccgccg
    62161 ccttcgcggg gcgtaccgcc ggaaatatgg tatttctcga tcagtttatg gtgctcctga
    62221 taaaaatggt tcaccgtttt taaccagtta tgggcgattt catcgcccag catatcgtcg
    62281 ccataccgtt tgaagccctg aatcgccatc cattgcagcg gcgcccagcc gttcggttta
    62341 tcccactgtt cgccggtttc gtattcggtc gccataatcc cgccgggcgt taacagacgg
    62401 ctgcgtacta catttgccag acggtcggcc tgctcatggt tcgccatacc gacatacagc
    62461 ggcacgatac tggcggcgga aaagagcgcc atttcttcgc gtcgccagtc atagtcccga
    62521 taacagccgt tttcatcatc ccacaaataa tggttcacgg cggcgcgtcg atcgctggct
    62581 ttctggcgaa atagcgcctc ggtgtcacgt tcgcctttca gcgctgaaat attggcgata
    62641 gcgctctcca gtttatacag aaaagcgttc aaatcgatag ggataaactg agttgtacgt
    62701 atgctggcaa gccggcccgc atcgcgtagc cagcgtgaag aatagtccca gccggacgcc
    62761 gccccggcgc gcaaatcccg gtagacttca ttgggcggac gaccggaatg ttttgcggtt
    62821 tcgacatctt ccagccagga ctcgtcgcgc ggcgtgtcgc gatcgtccca gtagcggttc
    62881 agcagggaac cgtccggcat ccgcacaacg tggcgataag cctggttgag cgccagcgat
    62941 tcggcgccgt ccatccagaa ggcgtattcc attttgagat ggtcgagata acgccgcgcg
    63001 ccgcgcacgc catcttcttc gaacagttca accatcaggg cgaaaaccgg cggctgcgag
    63061 cggctcagat aataggtgcg gttgccgttg ggaatatgac catagttttc aatcatccag
    63121 gcgaaattat ccgccataca tttaagtaag tcttcgcgcc cgctttccgc cagacccagc
    63181 atggtaaaat aagagtccca ataataggtt tcgctaaaac ggcctcccgg cacgatatag
    63241 gattgcggca gcgccagcag cgaagaccac ggaatatgat cctgcggttc gcgcgtcagt
    63301 atcggccaaa gctggtcaat atgttctttg agcgagtttt cggggttaga gacatactcg
    63361 ctggataagg tttccggtag ccagaaatgg ttctcgacga agcggcgtaa gtcaaaatca
    63421 cggtggcgtc tgaccttacg gtagcggatc aggatatcaa gcgggtccat cttcggcgcg
    63481 cagtccggga acgttttact gtctggaaac agttttgttg actgtacatg ctcgaacagt
    63541 tcgagatacc gatcggcagg ggtcagggcg tcagaggcgg gaagcccctc gatcatctcc
    63601 ggctccggtt ccgcctcgat catttcatcc agctttaact cgcacgggtc tgtttcataa
    63661 aacagatcga catcaatagt cagatcttca gaaggcgtgg ggtttaattt ctggttgagc
    63721 ataatgacaa ggacctccgg cttgcgtcgt aaaagatacg ggtgttgccc ggctgtctat
    63781 taagcgtaga cattcgcttc gatacctgag tggcaaagtg tgcggtagat cacattttgc
    63841 aatttatctc tcaaaaaaac acttcataac ttactgaata gtattgcgaa aatcctattt
    63901 tcatgacgcc tccctcagac ctaaaatcag aacattcgtt tcatagtggt atcactacgt
    63961 caccacatgg cgtggattca caaacaaagg taacgtaaat agttataata caagctatgg
    64021 caccatgata atacaaatgg atacaaatga tcgagcaacc cgacagtaaa agcgccaaac
    64081 cgctttataa gcagcttgaa gacgccttaa aagaggctat tgcgcgtgga gagtataaac
    64141 caggccagca gatcccgacg gaaaatgaac tgagcgtgcg ctggcaggtg agcagggtca
    64201 cggtccgtaa ggcgctggat gcgctgacgc gtgaaaattt gctgacccgt gtctccggca
    64261 aaggcacctt tgtttctggt gagaaatttc agcgtagcat gaccggcatc atgagtttca
    64321 gcgagttatg ccagtcccag ggacgtcgcc cggggtcacg caccatcaaa tccgtttttg
    64381 aatcggtaga cgatgagaca aaagcgttac tgaatatgaa cgatggcgaa aaagcggtcg
    64441 tcattgaacg tatccgctat gccgacgatg tggcggtatc gctggaaacc gtacatcttc
    64501 ccccacgttt tgcgtttttg ctggacgaag atcttaataa tcactctttg tatgaatgct
    64561 tacgcgagaa ataccattta tggtttaccc actcccgtaa gatgatcgaa ctggtttatg
    64621 ccagctttga agtcgcccat tatcttggcg ttaacgaggg ttatccgctg atcctgataa
    64681 aaagtgaaat gattgataac aaaggagaac tctcctgcgt ttcgcaacag ttgattgtcg
    64741 gcgataaaat acggtttacc gtatgatgtc agcattacgc taacgaagag caggctgaat
    64801 cgggatccag atcgcggatc ccgatttttt ttggtttcca tcttgatcaa atgtctttaa
    64861 atatcatata aaaataataa tacattatga gtcatttatg gcgaatcctc gcctgtatca
    64921 ttgatggaac cagaggaaag catgatgggt atgaaagaga cagttagcaa tattgtgacc
    64981 agccaggcag agaaaggagg cgttaaacac gtctattacg tggcgtgcgg cggttcttat
    65041 gcggcgttct atccggcgaa agcattttta gaaaaagaag cgaaagcgtt gactgtcggt
    65101 ctgtataaca gcggagaatt tattaacaac ccgccggtag cgctgggaga aaatgccgtt
    65161 gtggttgtcg cctcccacaa aggtaatacg ccagagacaa ttaaagcggc tgaaatcgcc
    65221 cgtcagcacg gcgcgccggt cattggttta acctggataa tggattcacc gttggtggcg
    65281 cattgcgact atgtggaaac gtacacgttt ggcgacggta aagatattgc cggagagaaa
    65341 acgatgaaag gcctgctgag tgcggtcgaa ctgctccagc agacggaagg gtatgcgcac
    65401 tacgacgatt ttcaggatgg cgtcagcaaa atcaaccgta tcgtctggcg tgcttgcgag
    65461 caggtagcgg agcgtgcgca ggcgttcgcg caggaatata aagacgataa agtcatttac
    65521 accgtcgcca gcggcgcggg ctatggcgca gcctacctac agagcatctg tatctttatg
    65581 gaaatgcaat ggatacattc cgcctgtatt catagcggtg agtttttcca cgggcccttt
    65641 gaaattaccg atgcgaatac gcctttcttc ttccagtttt ccgagggcaa tacgcgggcg
    65701 gtggatgaac gcgcgttaaa cttcctgaaa aaatatggcc agcgatatta tcctgaaact
    65761 ttcacagaag gtgaatgcgt tattggcgcg ggatgatgtt gacggtgtgg tcattactca
    65821 tggcactgac acgctcgatg aaaccgccta ctttcttaat ttgaccgtga aaagcgacaa
    65881 accggtggtg tttaccgctg caatgcggcc cgcgtcggca atcagcgccg atggcgcaag
    65941 gacagccagg gctggtgtct gactcgctca acccggcgaa ggcgcgggtg ttactgatga
    66001 tggcattaac tcagacgcgt aatccggaac tgatccagag ttatttcagt acgtattaat
    66061 catgaaggcc tgtgcgccca ccctcgaaga tgggcgcaca agatattaac gcatggtcac
    66121 aaactcttcc gatgcggtcg ggtgaatagc gacggtatta tcgaagtctt tcttggtagc
    66181 gcccatcttc agcgccactg cgaagccctg caacatttca tccatgccga agccgatacc
    66241 gtggataccc acaatttttt cttccggccc gacgcagacc agcttcatac ggcacggctg
    66301 gcggtgcgtc gtcaccgcgg tatacatagc ggtaaacgat gatttataga ctttcacctg
    66361 ctcgtcgccg tactgctcgc gcgcctgcgg ctcgcttaac ccgacagtgc cgataggcgg
    66421 atggctaaag accacggtcg ggatgttgct gtagtccaga tgctcgtccg gcttgttgtt
    66481 aaacaggcgc tcggagagac ggcgaccggc ggcgacggcg actggcgtta gttctatcgc
    66541 gccagtattg tcgccaacgg cgtaaatgcc ttctacgttc gtgttctgcc atttatcaac
    66601 gatgatgtaa cctttttcat tggttttcac gcccgctgcc gccagattaa tattgtcggt
    66661 cgacggttcg cgaccaatgg cccagatcag gcaatcaacg gtttcactgc ggccatcttc
    66721 cagttccaga gtcagactgc cgtcggcgtt tttcaccacc gctttcggca cggcgtgagt
    66781 atgcagttgc gggccttcgg cgttcatcac ctcaaccagc gtttcgctaa tcatcgggtc
    66841 aaaactgcgc agcggcgcat gtttacggac aaacagatgc gttttcgccc ccagcgcgtt
    66901 gataacgcca gccagttcaa cggcgatata acctgcgcct accaccgcga cgcgctccgg
    66961 caaggcagat agcgcaaaga aaccgtcgga atcaatgccg tattccacgc ctggaatgct
    67021 cggatggctc ggacggccgc cggtagcgat caaaatatgg tcagcggtga tggtttcgcc
    67081 gttcacttca atggttttgg catcgacaaa gcgggcaaag cctttaatca catctacgtt
    67141 atttttgccc agcacgttgt cgtatgaagt atggatgcgg tcaatatacg cggtacggct
    67201 ggcaatcagc ttgctccagt cgaactgatt aatcgtggtg tcaaaaccgt agtccgggcc
    67261 atacagatga atcgcttcac gaatctgcgc ggcatgccac atcactttct tcggcacgca
    67321 gcccacgtta acacaggtgc cgcccagctc tttggcttcg atgagcgcgc atttctggcc
    67381 gtacatagcg gcgcggttaa tcgaggcgat accgccgctg ccgccgccga tagcgatgta
    67441 atcatagtgt ttggtcatga ccgctccttt atgttcgttg tcggacggat agattctgcg
    67501 ctacccgcca aaatattcgc gattgtatac ctgaaggtga aaggttccac cgatggctgt
    67561 gattactccg gcacgatcca gcttaccgaa gtgtgtccgt gaccgtttgg cgccaacctg
    67621 ctgtgcagcc acggtagcac gttgttcatc tgctgctcca gtttccacgg cgggttaacc
    67681 acgatcatac cggacgccgt catcccgcgc tgatcgctgt ccgggcggat cgccagctca
    67741 atttgcagga ttttacggat gccggtggcc tccagctcat gaatcatgcg cttaatttgc
    67801 tggcggagta ccaccggata ccatagcgcg tatgtaccgg tggcgaaacg tttataaccc
    67861 tcgctgatgc cgctgactac cgcctggtaa tcggttttca tttcataagg cgggtcaatg
    67921 agaatcagac cgcggcggga aaccggcggc aatttggctt tcagttgctg atagccgtca
    67981 gcgcgttcca cgcgggcgcg gttgtctttt tgaaactccg cgcgcaacag tgggaagtcg
    68041 ctgggatgca attccgtgag ttgcagactg tcctgctcac gcagcaactg gcgggcgatt
    68101 aacggggagc ccggatagta gcgtaactgc ccgctgcggt tgaaatgttt tacgacgcta
    68161 atatacggtt ccagttcggc gggcagatcg tcctgctgcc agatacgggc gatgccttcc
    68221 agatactctc cggtacgttc agcatgttcg ctgcccaact gataacgccc cgcgcccgcg
    68281 tgcgtgtcca gatagagaaa cggtttttct ttctctttta gcgactcgat gatcaggctc
    68341 tgaacggtat gtttaaggac gtcggcgtgg ttgccagcgt gaaagctgtg acgataactg
    68401 agcatggatg cagatattcc gggaagtaaa caagttagcc gatagtttac cgcagatccg
    68461 tagagattac cgctcttgcg cttttatcgc cgttggccag gaggaaaaac aagtaggctg
    68521 tggcgtcaga gcgtaaataa cgtcaacgaa gtgatgcagg cgtctggatt ggcctgtttc
    68581 acggtcttaa ggaaggtggc aaaatttcga ttgaataggg tgtagttatg aaggaagcgc
    68641 gtctgttttc tttgcccttc cgctgttatc cagtcgactg accagactga acgaccactg
    68701 actctcgttg ttcccggttt cgcctcaata atgctggtga gtggtatcgc ggtggtgata
    68761 ccgtccgcga cctcatagag gtactgcatg tcaaagtagt aatccgcgtt atagccgcga
    68821 gaactgccaa attttcgcag catcagcgaa gaagatgaaa ttaatttacg gccatcttgc
    68881 agatgcttac tccgacggaa aatttttcgc ccagggaaaa taaagaaaac aataaatatc
    68941 agtacaataa cctgtaataa cgtggtcata tacaatcctt gtattccaga aacgaaaaag
    69001 ttgagaatat tatacatggg cagtttgcgc aaaaatgaca gcgattgatg tcacggccct
    69061 gttttcagaa aaacacccat gaaaagccta tctgaattta acgctaatca tgccgcgacg
    69121 cgtccaccga cttacccctg tcgggtctta ttctgaaatc gtttttatta tgatgatagt
    69181 gctggtttta ccttgtttat ttgattaaaa cgatagcgct aataatagaa aagaaaggat
    69241 tcattgatgt tccattatgg aaaatgtgtc gttcgcacgt tgtttttatt actggtttgc
    69301 tgttcgctgt cgggctgtct ttcatttggg ctgatacttg ccaccgataa agatggcaat
    69361 cgtcatcagt ctacctggaa atcggatacc gttaccgcgc tttccttagg taaagatagc
    69421 aacgggaaaa cgggctgggt gtttgttggc gaacattttg actacctgtt gacccagggc
    69481 ggcgataatg tggtggcgct gttaaaagat gcgactattc gccgggataa aatgcgagta
    69541 aaggatggtg ttaaattcct gattgataca gataagaagg agtttacggg tgaagtcaat
    69601 gtgacttacg cctgggtgga cgagaaagat aaactggcgg cggtaggcta cgggtttatt
    69661 tgtgcagacg gcgcggtaaa ttgcacgcta tccgtcatgg acctgaaagg gactatccat
    69721 cagaaaaata aagagcagag cgttacgcag cagctatcgt tctatcatcc tttcaccgtt
    69781 gagttctatc agtatcagcg cagtatgtcc ggggcaaaat ttggcagagt gttgctgccg
    69841 gtaactttgg cgctggatat tgtcactatg ccgctacagc tactgatctt cagtcgttaa
    69901 aattggattc agcagcaatg cctacgttcg gatgctggcg ttgctgcacg ggtgaaatga
    69961 gcgcccacca tcattgaaat tcccccaact atcccccatt ctagatccat agcgaaagcg
    70021 cgatagagcg cttcatttct tttttagacc aggactgcgc atatgaccaa tccattacta
    70081 acgtcttttt cactgccgcc tttttctgca attaaaccgg agcatgtggt gcctgcggtc
    70141 accaaagcgt tggccgattg ccgggcggcg gtagaaggcg ttgtggcgca tggcgcgccg
    70201 tatagctggg aaaacctctg ccagccgttg gcggaagccg acgatgttct ggggcgtatt
    70261 ttctcgccaa ttagccactt aaactcggtg aaaaatagcc cggagctgcg tgaagcctac
    70321 gaacagacgt taccgctgct gtcggaatac agcacctggg ttgggcaaca tgaaggactg
    70381 tacaacgcgt accgcgacct gcgcgacggc gatcattacg ccactctgaa taccgcgcag
    70441 aagaaagcgg ttgataacgc gctgcgtgat tttgaactgt ccggcatcgg cctgccgaaa
    70501 gagaaacagc agcgttacgg tgaaattgcc acccgcctgt ctgagctggg caaccagtac
    70561 agcaataatg tgctcgatgc caccatgggc tggacgaagc tcatcaccga cgaagccgag
    70621 ctggcgggaa tgccggaaag cgcgctcgcc gccgctaaag ccctggcgga agccaaagag
    70681 caggaaggtt acctgctgac tctggatatc ccgagctatc tgccagtgat gacctactgc
    70741 gacaaccagg cgttgcgtga agagatgtat cgcgcctatt ccactcgtgc ctccgatcag
    70801 gggccgaacg ccggtaagtg ggataacagc ccggtgatgg aagaaattct tgcgctgcgc
    70861 catgaactgg cgcaactgct gggcttcgaa aattatgccc atgagtcact ggccaccaag
    70921 atggcggaaa atccgcagca ggtgctcgat ttcttaaccg atctggcgaa acgcgcccgt
    70981 ccgcaggggg aaaaagagct ggcccagctg cgcgccttcg ccaaagccga atttggcgtt
    71041 gaggaactgc aaccatggga tatcgcgtac tacagtgaaa agcaaaaaca gcacctgtac
    71101 agcatcagcg atgagcagct acgcccgtac ttcccggaaa acaaagccgt gaacggcctg
    71161 tttgaagtgg tgaaacgtat ttacggcatc accgccaaag agcgtactga tgttgatgtc
    71221 tggcacccgg aggtgcgttt cttcgaactg tatgacgaaa ataacgagct gcgcggcagc
    71281 ttctaccttg acctgtacgc gcgcgaacac aaacgcggcg gggcgtggat ggacgactgt
    71341 gtcggccaga tgcgtaaagc ggatggcaca ttgcaaaagc cggtcgctta tctgacctgt
    71401 aatttcaacc gtccggtgaa cggtaaaccc gctctgttta cccatgacga agtgatcacc
    71461 ctgttccacg agtttggtca tggcctgcat catatgctga cccgcattga gaccgccggg
    71521 gtctccggta tcagcggcgt gccgtgggat gcggtcgaac tgccaagtca gtttatggaa
    71581 aactggtgct gggagccaga agcgctggcg tttatctccg gccactatga gaccggcgaa
    71641 ccgctgccga aggaactgct ggataaaatg ctggcggcga aaaactatca ggcggcgctg
    71701 tttattctgc gtcagctgga gttcggtctg tttgatttcc gtctgcatgc ggaatttaac
    71761 ccgcagcaag gagcgaaaat tcttgatacg ctctttgaaa ttaaaaaaca ggtcgccgtg
    71821 gtgccgtcac cgacatgggg ccgtttccca catgcgttca gccatatctt tgctggcggc
    71881 tatgcggcag gctactacag ctatctgtgg gccgacgtac tggcggcgga cgcttattct
    71941 cgctttgagg aggaaggcat tttcaaccgt gagaccggtc agtcgttcct tgataacatc
    72001 ctgactcgcg gtggttctga agagccgatg gaactcttta aacgcttccg tggccgtgaa
    72061 ccacagctgg acgcgatgct ggagcattac gggattaaag gctgatttta cgtgcaaatc
    72121 tgcttaatgg atgaaacggg cgccacagac ggcgccttat ctgttctggc tgcccgctgg
    72181 ggactggagc atgacgaaga caacccgatg gcgctggtat tgacgccgca acatctggag
    72241 ctgcgcaagc gcgacgaacc gaagctcggc ggcatttttg tcgattttgt cggcggcgcg
    72301 atggcgcacc ggcgcaagtt cggcggcggg cgcggcgaag cggtggcgaa agccgtcggt
    72361 atcaaaggcg attacctgcc ggatgtggtt gatgccacgg ccggactggg gcgcgatgcg
    72421 tttgtgctgg cgtccgtcgg ttgccgcgtg cggatgctgg agcgtaatcc ggtggtcgcc
    72481 gcgttgctcg acgacggcct gacgcgcggc tacgccgatg cggacattgg cggctggctt
    72541 caggagcgtt tgcagttgat tcatgcttcc agcctgacgg cgttaaccga tatcacgccg
    72601 cgcccgcagg tggtctacct cgatccgatg tttcctcacc ggcagaaaag cgcgctggtg
    72661 aagaaagaga tgcgggtgtt tcagtcgctg gtggggccgg atctcgacgc cgacggactg
    72721 ctggaaccgg cgcgtcagtt ggcgaccaaa cgcgtggtgg tcaaacgtcc cgattatgcg
    72781 ccgccgctgg cggatgtcgc gacgcccaac gccatcgtca ccaaagagca tcggtttgat
    72841 atttatgccg gaacccctct gacggagtaa cggattgccc gatggcgcta cgcttatcgg
    72901 gcctacgatt ctcaattatt tgtaggccgg ataaggcgta agccgcatcc ggcactgagt
    72961 attactgttc ggtaccttgc gtattaatca ttcggtttaa ccacggcacc ataatggcca
    73021 tcaccacggt gaccgccagc gttaccagac caattttgct aaagacgccg gtataaatgg
    73081 gcagcgtctg taacggatcg gtgatgtttt ccggtacggc agtgaaggtc gccacataac
    73141 cgccgagcag gaaggcggcg gcctgggtca ggaaccacat tcccagaata aagcccatca
    73201 gatgctgcgg caccagagcg gcgaccattg ccagtcccag cgcgctaatc agcaactcgc
    73261 ccagactctg gaacagatac actagcacga taaaccacgg cgacgtcaat ccttgcgcat
    73321 cggcaaacca catcccggcg gcggcggtca gaaaacccag cgcgcagagg aacatgccga
    73381 gcgtaaactt catcggcata gtcagatctt tgcctttgct acccagtcgg gtgtaaatcg
    73441 ctgccagtac cggactggcg acgaccaccc agaatgggtt cagcgcctga aaactcaccg
    73501 ggttaatggc gaatccaaga atttcatgat gcacgttatt aatcgcaaag aagttcagtg
    73561 aggtaggcat ctgcgcatac agaatgtaaa acagcacggc ttcaatcatc agaataaacg
    73621 ccacgaacat tttattgcgg ccggttttat ccagacgaaa cgcttcgcga aagaagaaaa
    73681 tagtgacgac gatagaaagg acgatgagca ccagattggc aatcttaacg ttgtgcatca
    73741 gccaggcgca gaggaaaatc atgacgacgg tgccgagtag taccagcagc aaattgcgaa
    73801 aacgtagcgg tttatgatcc ggttcagaac cgatattttt caccatgcca cggcaggcga
    73861 agtacaccag aagcgcaaca attaaaccag cgccgcacag attataggtc accgcatagc
    73921 caaatttatc ggcaatcacc ggcgccagcg atagcgataa caaagaaccg atgttaatcg
    73981 acatataaaa cagggtgaaa gcgccatcca gccggggatc tttaggctga tagcatttag
    74041 agagcaggct ggcgggattg gctttaaata acccgttgcc cacggcaatc gtacccagtg
    74101 cgataaaaat cagatcggga tttaatagcg acataccagt cataaaatag ccaatcgcca
    74161 gcacaatcgc gcccaggacc agggtgcgtt tagtccctaa cagatggtcg ccaacatagc
    74221 cgccgatgga gatcaggcca taaaccagcg ccgcaaaagc gccaaaagta ataaaggcct
    74281 gttcctgaga aaaacccaat tgtttaacga aaaagaccgc caggatgccc tggacgccgt
    74341 aatagctaaa tcgttcccat aattctacaa aaaagatcat gaagaatgga cgaggttgct
    74401 gcagcaagcc cgtaggtgca gttgtattca tattccttcg ccttttaatg ccatcccgaa
    74461 acgtatgaac gcgtatatca aaacgcgccg aaaagtctta ccctgatata gactgcggtt
    74521 attagcctga tcaataggtt attatacaaa tgatacgcaa actaattagt ggatcacact
    74581 aattatgttt ggtgtgatgg aatgatgtac tgagtactgc gaagaagggg ggataaacaa
    74641 aacgcccaca taagcgggcg ttgttgttga tagccggagt ttgcctgatg gttcaggcca
    74701 acctgattga ctatagacca gatgcggtct tagccgccag ccggcacggt aagtattact
    74761 cttcttcgtc gcgcagcgga acaatcagca tgtcaacgtg aacggtgttg atcagctggc
    74821 gcgcagaaga catcagtttg ctccagaagt cctggtgatg accgcaaacg accagatcca
    74881 tatcgtattt cttgatggcg tcaaccagca cctggcccaa atcgccgcta ccgctcaggg
    74941 tttcagtgat agggtagcca gcgttggtag acagctcggt cagcgcgtgg tgggtttctt
    75001 tggagatacg tttctgcata tcgcccagat tgacgtcaat cagaccggtg tacaggtctg
    75061 aatagttcac atcaacgtgg atgagggaga ttttcgcgtt gtaggggcgc gccatagaga
    75121 ccgctttttc aaccagaact ttactttccg gggagagatc aactgcgata agaatgtgtt
    75181 tataagccat agtgttactc cttccataag ttgtcgatga ccattgagct actggcgttt
    75241 cttatgccgc cgcgtcaccc gcgtcctgcg aactctatgc gcggggctag ctcagccgtt
    75301 taccataact atccttacat tatagcgacc aggataatcc gtcaatctgc cttgcttgcc
    75361 agttagttaa acaaaatttt cagggaattg cattgatagt gattaacctt ctggtaaaaa
    75421 aattaactga tctcctacaa tgtgtataag agccgttcga atgcggagcg ctaatatgga
    75481 cggctttcgt agtactcttt cactgattgt ctggcagggt atcggggagc ggtagtcccg
    75541 gagaggaact ccgtgggcgg gtcgccgggg aggagatatg ataagcaccg tctcactatt
    75601 ctgggcttta tgtgtcgttt gcattgttaa tatggcgcgc tatttctcat cgctacgcgc
    75661 actgttagtg gtacttcgtg gttgcgatcc tttgctctat caatatgtcg atggcggcgg
    75721 cttctttacc acgcatggtc agcccaacaa acaggtgcgc ctggtatggt atatctacgc
    75781 tcagcgctat cgcgatcatc atgatgaaga atttattcgc cgttgtgaac gcgtgcgccg
    75841 ccagtttctg ctgaccagcg cgttatgcgg tttggtggtg gtgagcttga ttgcgctcat
    75901 gatttggcac tgaataaaaa aagcgggcca gtttcctgac ccgctcgtat tagataagcc
    75961 tccggatgac gccgcttgta gcggcctgtc aggcctgtgt cgtttcatcc tgacaggccg
    76021 gattagcgac agcgctatcc ggcccatttg gcttaaataa tcttcaggga aagccagtac
    76081 agcacgccgg aaagaataat cgccgccggt aacgtaaata cccaggccat cagaatgctg
    76141 gtcacggttt tacgctgtaa cccgccgcca tcaacgacca tggttcccgc cactgaagag
    76201 gagagtacgt gagtggtaga aactggcata ccggtgtagc tggcaagacc gatagagact
    76261 gccgccgtca tctgcgccga cattccctgc gcatacgtca tgcctttttt accaattttc
    76321 tcgccgatag tggtcgccac gcgacgccag ccgatcatcg taccaatacc cagcgccaac
    76381 gccactgcca taatgatcca caccggcgca tactcaatgg tgcttaacat atcggtcttc
    76441 agctttttca gcaggcgctg gtcatcgctg cttacgccag gcaatttcac gactttgtcg
    76501 gtcgtgtcgg aaatgcacag cataatgcga cgcaactgac tacgctgttc aacgcttaac
    76561 ttgtcgtagc tttccacgtt tgccagcatc cctttcgcac ggttaagcgc gttaatggtg
    76621 ttagccggat ggcagtggaa ttcagtcggt tcagtcgcgc ccggttccgg agagggaatc
    76681 agttggtcaa cgccggtgac ggctttcagc aggtcaggac gctgctcaaa gtacgtttcg
    76741 acattgttga tagcatcgcg cgtacgggtg atttcgtagc tggaggcatt catattgacc
    76801 acgaaacccg caggcgcgac gccaatcagc accagcatga ccaggccaat gcctttctga
    76861 ccatcgttcg cgccatgcga aaacgccacg ccgatagctg agaggatcag cgcgatacgc
    76921 gtccagaatg gcggcttttt cttgccgtct ttcttttcac gttcggctgg cgtcaggtgg
    76981 atacgggcgc gtttcttagt accgctccag tagcggcgca gcaagaaaat cagaccgccg
    77041 gcgaatacca gaccgacaat aggggagata atgagtgaac cgaaaatatt gataactttc
    77101 gggatgttaa gcgcatccac cactgacgtg ccggtcatca tcgcattggt taaaccgatg
    77161 ccgataatgg cgccaatcag cgtgtgggaa ctggacgccg gcaacccgaa ataccaggta
    77221 ccgaggttcc agataatcgc cgccagcaac atggaaaaga ccatagcgag gccgtgcgcg
    77281 gaacccatgt tgagcaggag atccgtcggt agcatatgca caatggcata cgccacgctg
    77341 agacccccca gcaaaacgcc aaaaaagtta aacaccgccg ccatgacaac cgccagctgc
    77401 gaacgcatcg cacgggtgta aatcacggtt gcgactgcat tggctgtatc atggaaaccg
    77461 ttaatcgctt cgtagaacag cacaaaagcc agagcaagca ataataaaag cccggtatgt
    77521 aaatccaggc cagcaaacaa atgtagcata ggacgttacg ccattttgag gacatgaacg
    77581 cggcgcatta tcagtgactt tggcggcgcg ggcaaagtga aatatagact ttttttgatg
    77641 tacttcgtgc tttgtttgat atcactaaag aattatctta tatatttcag ataaatacca
    77701 ttttcaggcg cttttcgcgc tggtgcgacc actgaggaaa ctttacaatt ctcgcccgaa
    77761 tttgagagag gaaggcgacg tggaaaggtt tgatgctgtt attataggcg ctggcgcagc
    77821 gggcatgttt tgcgccgcac aggcaggaca agcgggtagc cgcgtgctgc tcatcgataa
    77881 tggcaagaag ccaggacgta aaatcctcat gtccggcggt gggcgctgca actttactaa
    77941 tctttatgtt gagcctgctg cgtatttgag ccagaacccc catttttgca aatcagcatt
    78001 agcccgctat acccagtggg actttatcga tctggtcggc aggtatggga tagcctggca
    78061 tgagaaaacg ctgggacagc ttttttgcga tgattccgcc caacgcattg tcgatatgct
    78121 ggttgccgag tgcgacaaag gtggcgtaac gatgcgcctg cgtagcgagg tattgagcgt
    78181 cgagcgtgat gagtcgggtt tcgtactggc gttgaacggc gagacggtga ctacgcaaaa
    78241 gctggtgatt gccagcggcg gcctgtcgat gccggggctt ggcgcatcgc cgtttggcta
    78301 taaaatcgcc gaacagtttg gtctcaaggt gttgccgacg cgcgccgggc tggtgccctt
    78361 tacgctacat aagccgctgt tagaacagct ccagacgctg tctggcgtct ctgtgccctg
    78421 cgtgattacc gcccgcaatg gcacggtatt tcgggaaaac ctacttttta cccatcgtgg
    78481 gctgtccggc cccgccgttt tacagatttc cagctactgg caaccgggcg agttagtgag
    78541 cattaactta ttgccggatc tctcgctgga agacgttctc aatgaacagc gtaacgcgca
    78601 cccgaaccag agtctgaaga acacgctggc gatgcatctg ccgaaacggc tggtggagtg
    78661 tttacaacag ttggggctca tcccggatgt atcgctcagg cagttgaacg ttcgtgacca
    78721 gcagacgttg gttgacacgc tgacggcctg gcaagtacag cctaacggta ccgaaggcta
    78781 tcggacagcg gaagtgacgc tgggcggcgt ggatacaaac gaactatcat cgcggactat
    78841 ggaggcgcgc cgcgtgccgg gtctctattt tatcggcgaa gtgatggacg tcaccggctg
    78901 gttgggcggc tataacttcc agtgggcctg gtcgagcgcc tgggcctgcg cgcaggattt
    78961 gattgcgtta aaaattaact aattgatatt atgtgttttt cggtctcatt tgactgatcg
    79021 ccgtatatct tggcctatag catcttttag tcagaagtat tctggataag gggcactcat
    79081 tttgcatggc atgaccaccg atttcgtttt aacaatgggg aatgcggacg gtagttttcg
    79141 ctataaggtc gtggcagtaa aaccagataa attggtttca gctcgggagc ctgaataact
    79201 ttagattgaa catctgttct ggatgttact ttgggttgat ttcccgattt gcgttgactc
    79261 aaaacagaat caagtttaga gataaaaatg tgttagacga tatctataat cagaatgaaa
    79321 catgtttaac cattttcatt atgaatgcat taatctcagc tgggttttga agcagaccgc
    79381 attcaggtcg gatactggcc aacaacacca gatacagaat aaggcccctg acagggcctt
    79441 ctggtagtat gtagtcgata tttacactgt ttacaacggg gagtcatact ttcttattaa
    79501 tcctgtaaag caaaccactg cacagtgcgc cagcaaaaag aacaactgca atagtggcaa
    79561 acatcagcgt atatgcaaat tctttatacg tatcaagaag gtatccgaag ataagatgga
    79621 cataagcttc cgggctgaat ccgatgcaga ttaatatccc cattgcggtc ccggtaaaca
    79681 ctttcggtat gcgaatttca tttacctgcg catacattat accgcgcatg ccaaacgtaa
    79741 gcgctcccag taataaaacc agagtaataa gcaggatcag aaatcgtgag tcatgaggaa
    79801 taaatataaa agatgcagtt atcaatgcac cgagaataaa gaagctggcc ataactttca
    79861 gggaagaacc aatcttatct gcaagtaggc cagcaaaagg cgaaataata aaagcgagaa
    79921 aatatgccct aatcatcccg ataacggcag tttggtcggg agtcattcca taggcatcgg
    79981 agaggtatgg taccagataa gctccgccct ggtaaacaaa aataacacag ctgataatga
    80041 atgctgccag ccaaagtttt acacttttga gtagtgaaat aagatccgac atttttttag
    80101 gtgccgcatt ttcaatagca ctaacacctt tcggaaataa ataataagag gtgaatccca
    80161 gaataatata aatggctgcg tcaaatcgta aaataaaacc aatgctgaca gcactggagc
    80221 catgcagacc aacaatagcc acggcacata acgtcagaac agtgccggca attccacgac
    80281 cggactccag aaatccaaaa taccgcccct gctcattgtc tgatgcaagg agtctggcaa
    80341 tttttgtcat ggaaaccagg aacagtccat taccgactaa ggacataaat ccgacgataa
    80401 taaacatggc ctgataggaa ggccggaagg actgccagat ggcaagggcc gccattgtga
    80461 gataggcaat ggtaagaatg cttttaggat ttttgaaacg gtcaacgatg atgcctgaaa
    80521 cagcacctga tataatgcct acaaacccga gccagctcat taacatgccc gattgtgtat
    80581 ttgtcagtga aaagtattca ttccacggat agtagaatac ttcacgcaaa tacatagcct
    80641 tgaatattgt tcccccaccg actgccagaa gaataaaaaa atcaggttat gccttttaat
    80701 cgatttgtct tctgcatgtt ccatatgtcc gcctgtataa ctagacgtta ttgtagattg
    80761 atccgttagt gtcttgtgtt attttaattt ttgtatgtat ttataaacag tgggttcaga
    80821 tatgttaagt tttttggcta ctttcgttac tgccccttta agcagaaata cgccttcatc
    80881 atttagtaat gaaataatat ggcttttatt ttcagcattc agtgactctg gattaatatt
    80941 ttcaatattg attacattat taattttgag atcaaccatt tcaggaatgg tcagtccaat
    81001 atgttcatca agctgagtgc cgttattatt gtcagtctgc ccgacaaaaa tgcttaaaaa
    81061 atgactaagt ttatcattca gggcaattaa atcttcgacg acggtattca gacatagtgc
    81121 accaacaatt tctccctgct tattccggat aaaaaaagtg gcacacttaa gccgtctgcc
    81181 atcgcgtgtc ttgctgagat aattacactg gtaatgtacc tcactgtcat tgttcttcat
    81241 ggcacggact accagatcgg tgatgggatc tccgacagag cgaccgctga tatgtccatt
    81301 tctgatttta tgtatagaag actcaagatc agaaagattg tgcagaacaa cttccgtgtt
    81361 ttcgccaaaa taatcggcca ggaaatcgat caaaaattca tagggttcaa gacaagtgtt
    81421 tttcatggtt aatctggttg ccacctcagt ggcaaccacc tttgttattg acgaaatgcc
    81481 acagcttcaa tctcaactct ggcacccata ggaagtgttt ttacagcaaa acagctgcgt
    81541 gccggcggat ttatcttaaa aaagctggca tagacatcgt tgaacgcagc aaaatcagcc
    81601 atatcactca agaaacaggt cgttttcagt accgtatcag tatcaccgcc tgccatctta
    81661 actacagcca gaagattaag cagtgactga cgggtctgtt cctgaatatc atcagtttca
    81721 attttgccac tgtcagcgtt aatgggcaat tgtccggagg taaaaattaa attacccatc
    81781 gcattgccct gactgtatga gccaattgct gccggtgctg tttctgtaaa aataatctct
    81841 ttcacttctg ttccttaaaa atacttactg aatgcctttt ccagacgact cagtgcttca
    81901 tcaatacgtg actccggaac accacagtta attcgggcaa atccggtacc ggcaacacca
    81961 aactgatctc cccggttaaa tccgagtccc gcatcctgca ctaaaaattc ctgaatgcga
    82021 tcacctgacc agcccgtatc attaaagtcg gcccatacaa gataagtggc ttccggcaga
    82081 ttggctttta ccggatatgg catgttattg agcccgttaa ccagtttaat ctgcatttta
    82141 cggatatgat tcaccacctc ttcacgatag tcatggtaat atttatatcc ggcataggcg
    82201 gcttcatgcg cgaacgcagt gggctgaaaa tgtaattctt tcaggacaac tgccatctgt
    82261 tttttaaata caggatcggc cgtgaagaca taggaactaa aaataccgcc aatgttaaac
    82321 agcttccctc cggataaaaa aacgataatg ccatttaaat tttccgcagc tttcatgacc
    82381 ggcgtatagc atttttcgtc atagacaaaa tctgcatgaa tttcgtcaga aatcaggatt
    82441 gttcctgttt tctgggcaat tgcggcgact ttcctgactt cctcttcagt ccagcaacga
    82501 cctaccggat tatgagggtt acagaaaatc agaatcttat tctccgggcg tgaacaggta
    82561 tcttccagct tttcaaaatc aatagtgtaa tgattgtttt catcacgcag cagatcacac
    82621 tcagttacag cacggtggtt ttcacggatg gttctggcaa aagaatgata gaccggtgtc
    82681 ataaccacaa cggattcatt acactgtgtc attcccctga taaaagcgcc catcgtcatc
    82741 agtaaaggcg gtgtttcaat aatatcagcc gtatccggcc gccagtcata atatcgatca
    82801 taccaggatg ccagcacatc cttaaaatca tcatgatagg ccggatatcc gaattctctg
    82861 cggttacaga cttcaatcag tgcctgacga acctccacgg gagaaactaa atcggtatct
    82921 gcaacagaca taggtattac tggaaatcca ttaatgacac tgtcatattc ccatttttct
    82981 gatgctattc tctgatagat ttcattaaaa tcgtatttca ttttattttc cttaatttat
    83041 tcagccgcag tccggaaagt atctgccggt ttaccatcca ttttcttaaa tgccgttttg
    83101 gcattgcgga gaagtaaaag tgaagtgaat acagcgagag caaacatggc acccatgaag
    83161 ataaacatgt aggtgtaacc ctgtacttta tatgcatcaa gccagtaccc gaataacgca
    83221 tggataaaca tttccggaga gaatcccaca gtggccatga tccccataac ggtaccggtc
    83281 agacgaacag gaaccttcat ttcctcaatt tgcgcataca tgatcccgcg cagagcaaag
    83341 ttaatggagc ctacaatcat cagggtgccg atcaggaccc ataccatagc cggatcctgt
    83401 gggatcacca ggaacatggc gacaccaatc accccggcaa taaacagcca attcatcacc
    83461 ttaatcgctg agccgacttt gtctgcgagc agacccacaa ccggtgcaat caggatagcg
    83521 aggacataag cacggatcat accgataatt ccggcatgtt cggcggtcat tccgtagaca
    83581 tcagacagat aaggaaccag atatgaggac ccctgataga aggagatggt tgcaaagatg
    83641 gagaaagctg caaaccagac ttccttaacc ttcatgacag ccagaatatc gtgtacagat
    83701 attttttcct tggccttttc ttctccggaa gcagaattat ggttatcacg gggcatggcg
    83761 aaccacatca gaacacccag cgctaggtag agaaagccgt atgcatgtag cacactgcca
    83821 atcccttcca cttcggttgc agacatggcg aaccatgcta cggcaacggc agagatggct
    83881 gacccagcga taccacgtcc ggactccagg aaaccaaaca gcttcccctg gtcactggca
    83941 ttaccaatca ggcgggttgc gcgcaccatc gatactagga aaagaccatt tgcgaggaaa
    84001 gatagtatgc cgatgatgac atactgcgta gccagacccg gtgctgttga ctgccataat
    84061 gtggttacgc ccacagccag aaaggtaaaa gaaataatca gtcgggtatt gttcacctta
    84121 tcgataatca ccccagcaat tgaagatgaa acaatcccca caaaccccag ccaactcatc
    84181 agcaggcctg aatccgtgtt attcactccc atgaattcat tccaggggta ataaaatact
    84241 tccctgaggt acatcgattt aaaaatggtc cctcctccga ttgccagaag aatgaccatc
    84301 aaccattttt gaaaattgga tgttttcata aaccttcgcc tgtcc
//
LOCUS       DAJVKX010000003        62753 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000003 DAJVKX010000000
VERSION     DAJVKX010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 62753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62753
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.003"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..846
                     /locus_tag="OPY25_000169"
     CDS             1..846
                     /locus_tag="OPY25_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose bisphosphate family class II aldolase"
                     /protein_id="HCS0925897.1"
                     /translation="MSSKNMLQKAQHAGYAVPAFNIHNLETLQVVVETAAEMRSPLIV
                     AGTPGTFSYAGMGNIVAIAGDLAREYNLPLAIHLDHHESLADIESKVMAGIRSVMIDG
                     SHFPFEENVALVKSVVDFCHRYDTSVEAELGRLGGIEDDLVVDSKDALYTNPQQAREF
                     VARTGIDSLAVAIGTAHGMYAAEPKLDFERLAEIRALVDIPLVLHGASGLPESDIRQA
                     ISLGVCKVNVATELKIAFSDALKEYFLQNPKANDPRHYMQPAKQAMKEVVRKVIHVCG
                     CEGQL"
     gene            857..1771
                     /gene="pfkB"
                     /locus_tag="OPY25_000170"
     CDS             857..1771
                     /gene="pfkB"
                     /locus_tag="OPY25_000170"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCS0925898.1"
                     /translation="MIYTLTLNSAIDMNIFSDPLQPNIVNRTHHTEFCPNGKGVNVAL
                     VLDHFQIPAHILGIFGGFTGHYIVESLRTRKMPVTPAWVEEPTRINIFIHDGKQEYKL
                     VNPGSYIPDECKKQIITIISQLPDAEYLVISGSLPQGIESRFYAEIMHICQQKNIGVI
                     LDISHPSLRQLLEFKPLLIKPNDEEVKAIFGLTVSDDNDAKNTLTTLHALGAQNVLLT
                     LGAKGMYFSNGIDYWFCSAPTVDLVSSACAGDAALAAFLSQWLSTGEVEYALSLASAT
                     GADVASSAGLGQLAAIETLLSQIHVRKL"
     gene            1798..3225
                     /locus_tag="OPY25_000171"
     CDS             1798..3225
                     /locus_tag="OPY25_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCS0925899.1"
                     /translation="MKKIIAVTGCPTGIAHTFMAEEALKNAAKKLSVEIKVETNGASG
                     VENAIQPADLVDIAGVIIAADKDVLPDRFNGLPVIEVPVKEAIHHPAELINKVINGEA
                     PIRKGESTTSTEIIEKESLGRQIYKHLMSGVSNMLPFVVAGGILIAVSLLWGIYSADP
                     NSAEYNATAAMLMKIGQQAFSIMVPVFTAYIAFSISGRPGMVAGFVGGLLANTTGAGF
                     LGGIIAGFAAGYLMLWVKNRLEGLPRQYEGLKSIFIMPLIGVLVIGVLMSLLGQPVAA
                     INNSMMNWLASLQEANPILLGIVVGAMCSFDFGGPVNKAAYVTGTLLLGQGNFYFMAG
                     VSAACITPPLVIALATTFFPKGFSEEERAAGMVNYILGCTHITEGAIPFAAKDPLRVI
                     PMMMIASSISAVLSYSLRIQVPAPHGGFLILPLVSQPLAWVLCILAGSACGAMMLGLW
                     RLWAVRKNSVNTTPVAKAGGQNAAL"
     gene            3212..4018
                     /locus_tag="OPY25_000172"
     CDS             3212..4018
                     /locus_tag="OPY25_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HCS0925900.1"
                     /translation="MQLCEHDIFISDERLDKVTALHRVVEKLSAAGNTTPDYLRGMLD
                     REAQISTYLGNGIAIPHGTPESRDAVLQTGVKVIVFRHGVDWGDGNTAYLVTGIAARS
                     NEHLEILRQLTRVLSDDAILQALAKAESPSQVLALLTGSTTNTPAAMELHEGEQATFV
                     IHNPHGLHARPSAVLVKFIKQFQSHITVENLDNASGPVDGKNLMRVVSLGAKKGHRLL
                     FRAQGEDAQQALREIGELIASGAGEMITVPVTPPPEVMQPKRSWLSRLFN"
     gene            4216..5487
                     /gene="gatZ"
                     /locus_tag="OPY25_000173"
                     /pseudo
     CDS             4216..5487
                     /gene="gatZ"
                     /locus_tag="OPY25_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462170.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
     gene            5502..5966
                     /gene="gatA"
                     /locus_tag="OPY25_000174"
     CDS             5502..5966
                     /gene="gatA"
                     /locus_tag="OPY25_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HCS0925901.1"
                     /translation="MSQLFVRTGITFDSSQQALAHIGKEMLAKGVVHDSYPQALVERE
                     ASFPTGIALERHAVAIPHCEAVHAKSPAIYLIRPDKPVMFQQADDDEEIAVSLIIALI
                     VENPAAQLKLLRRLFGALQIPDTIEALLSAPDAELASCFEHKVLTAEQCVQV"
     gene            5997..6281
                     /gene="gatB"
                     /locus_tag="OPY25_000175"
     CDS             5997..6281
                     /gene="gatB"
                     /locus_tag="OPY25_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HCS0925902.1"
                     /translation="MKRKVIVACGGAVATSTMAAEEIKELCDANHIELDLVQCRVTEI
                     ETYMDGADLICTTARVDRAFGDIPVVHGMPFVSGVGIEALQQKILSILMG"
     gene            6285..7658
                     /locus_tag="OPY25_000176"
     CDS             6285..7658
                     /locus_tag="OPY25_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCS0925903.1"
                     /translation="MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAEHFQINLHVIDVGWPGSSPMTWASQIALVAIPV
                     AIGVNVLMLVTRMTRVVNVDIWNIWHMTFTGAMLHLATGSYWLGILGVVVHAAFVYKL
                     GDWFAKDTRDYFGLEGIAIPHGSSAYLSPVAVLVDTIIEKIPGLNRIHFSADDVQKRF
                     GPFGEPVTVGFVMGLVIGVLAGYDTKAVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     HARKRLQAKFGGQEFLIGLDPALLLGHTSVVSASLIFIPLTILIAVLVPGNQVLPFGD
                     LATIGFFIAMAVAVHQGNLFRTLISGVIIMGITLWIATQTIGLHTQLAANAGALKAGA
                     QVASLDQGGSPITWLLIQLFTWQNIVGFAVIAIIYLAGVLLTWRRARQFVAAEKATAL
                     QQSQIAS"
     gene            7702..8745
                     /gene="gatD"
                     /locus_tag="OPY25_000177"
     CDS             7702..8745
                     /gene="gatD"
                     /locus_tag="OPY25_000177"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCS0925904.1"
                     /translation="MKSVVIHAEGDVRVEERPLPQLQAEDDVLVKVVSSGLCGSDIPR
                     IFAQGAHYYPITLGHEFSGYVESYGTGVTDMQPGDAVACVPLLPCFHCPQCERGYFSL
                     CKQYQFVGSRSEGGNAEYVVVKRANLFRLPSDMPIEDGAFIEPITVGLHAFHLAQGCE
                     GKNVIIVGAGTIGLLALQCARELGARSVTAIDINPQKLELAKALGATHTCNSREMTAD
                     DIQTALSDIQFDQLVLETAGTPQTVSLAIDITGPRAQLALVGTLHHDLTLTTRTFGLI
                     LRKELTLLGSWMNYSAPWPGEEWETAARLLAEKRLQLTPLIAHRGDAESFAEAVKALN
                     GAPMQGKILLQLS"
     gene            8856..9629
                     /locus_tag="OPY25_000178"
     CDS             8856..9629
                     /locus_tag="OPY25_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0925905.1"
                     /translation="MNSFERRNKIVDLINTQGSVLVMDLSNTFGISEVTIRADLRLLE
                     EKGLVTRFHGGAAKPGSHLAEGDNQEVILEDRYQLASDPKKRIAQAAAAMVEEGMTII
                     LDSGSTTLLIAEALARKSNITVITNSLPAAFTLSENKDLTLVVCGGTVRHKTHSMHGT
                     IAERSLHGISADVMFVGADGIDATNGITTFNEGYSISGVMAAAAHKVIAVLDATKFNR
                     RGFNQVLPMDKIDCVITDDTISKQDKAALAKTGVELMIV"
     gene            complement(9787..10650)
                     /gene="rsmI"
                     /locus_tag="OPY25_000179"
     CDS             complement(9787..10650)
                     /gene="rsmI"
                     /locus_tag="OPY25_000179"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCS0925906.1"
                     /translation="MKQNESADNSQGQLFIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLVAKLKEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDMVAVWGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEDDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALAQQEE"
     gene            10714..12765
                     /locus_tag="OPY25_000180"
     CDS             10714..12765
                     /locus_tag="OPY25_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator"
                     /protein_id="HCS0925907.1"
                     /translation="MVPSTFSRLNAARALPVVLAALLFAGCGTQAPDQSAAYMQGSAQ
                     ADSAFYLHQMQQSADDSKTNWQLLAIHALLKEGKSQQAVELFNQPPQNLNDTQRREQS
                     LLAVEIKLAQKDVAGAQALLDKLKPADFAPHQQARYWQAQIVASQGRPSLTLLRALIA
                     QEPLLAAKEKQKNIDATWQALSAMTPDQARTLVINADENVLQGWLDLQRVWFDNRNDP
                     DMLKAGIADWQKRYPQNPGAKMLPTQLVNVQRFKPASTSKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNLGTQAVEMQPVAAPDAPVEPSVEETQPQMTNGVASPSQASVRDLTDDAP
                     SQSATPVSAPQTPPAQPATASAPADPSAELKIYDTSSQPLDQVLAQVQQDGASIVVGP
                     LLKNNVEALMKSNTPLNVLALNQPETVRSFPNICYFALSPEDEARDAAHHIYEQGKQS
                     PLLLIPRSALGDRVANAFTQEWQKLGGGIVLQQKFGSVAELKMGVNGGAGIALTGSPV
                     AASVPAQPGVTIGGLTIPAPPTDAQITGGGRVDAVYILATPEEIGFIKPMIAMRNGTQ
                     SGATLYASSRSAQGTSGPDFRLEMEGLQYSEIPMLAGGNTPLMQQALSAVHNDYSLAR
                     MYAMGVDAWTLANHFSQMRQVQGFEINGNTGALTASPDCVINRKLSWLKYQQGEIVPA
                     S"
     gene            12723..13118
                     /locus_tag="OPY25_000181"
     CDS             12723..13118
                     /locus_tag="OPY25_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HCS0925908.1"
                     /translation="MAQIPARGDCSRQLTRKQAGDAWEAAARLWLESKGLRFIAANVR
                     ERGGEIDLIMRDGKTTVFVEVRYRRSGLYGGAAASVTRSKQHKLLHTARLWLARQNGS
                     FDTVDCRFDVLAFTGNEIEWFRDAFNDHS"
     gene            13140..13730
                     /gene="diaA"
                     /locus_tag="OPY25_000182"
     CDS             13140..13730
                     /gene="diaA"
                     /locus_tag="OPY25_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HCS0925909.1"
                     /translation="MLERIKVCFTESIQTQIAAAEALPDAISRAAMTLVHSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHHSARIQEMHMLTVNCLCGLIDNTLFPHQDD"
     gene            13740..14315
                     /gene="yraP"
                     /locus_tag="OPY25_000183"
     CDS             13740..14315
                     /gene="yraP"
                     /locus_tag="OPY25_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HCS0925910.1"
                     /translation="MKAFSPLAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLELRVSSALSKDEQIKKETRINVTAYQGKVLLVGQSPNSELSARAKQIAMGVE
                     GTTEVYNEIRQGQPIGLGTASNDTWITTKVRSQLLTSDQVKSSNVKVTTENGEVFLLG
                     LVTEREGKAAADIASRVSGVKRVTTAFTYIK"
     gene            complement(14382..15017)
                     /locus_tag="OPY25_000184"
     CDS             complement(14382..15017)
                     /locus_tag="OPY25_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCS0925911.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINTPQVSAIAAPTRRPLTDIVGV
                     YNPHDPQLTDALAQVTDPVDIVFCCLGTTRREAGSKAAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPRLTIARPSMLLGDRTTRRVNE
                     TLFAPLFRLLPGNWKSIDARDVARAMLAEALEPAQEGVTILTSSQLREKAG"
     gene            15148..15666
                     /gene="yhbO"
                     /locus_tag="OPY25_000185"
     CDS             15148..15666
                     /gene="yhbO"
                     /locus_tag="OPY25_000185"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HCS0925912.1"
                     /translation="MSKKIAVLITDEFEDSEFTSPAAEFRQAGHEVITIEKEAGKTVK
                     GKKGEASVTIDKAIDDVRPDEFDALLLPGGHSPDYLRGDSRFVDFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(15646..16089)
                     /locus_tag="OPY25_000186"
     CDS             complement(15646..16089)
                     /locus_tag="OPY25_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HCS0925913.1"
                     /translation="MDTLTAIGRWLAKQHVVTWCVHHEGELWCANAFYLFDAQNVALY
                     LLTDDKTRHAQMSGACAPVAGTVNGQPKTVARIRGVQFKGEIRRLEGQESDAARKAYL
                     RRFPVARVLPAPVWEIRLDEIKFTDNTLGFGKKLHWLRDSRAQQA"
     gene            16127..16444
                     /locus_tag="OPY25_000187"
     CDS             16127..16444
                     /locus_tag="OPY25_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462184.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCS0925914.1"
                     /translation="MLMATMTPWYLYLIRTADNALYTGITTDVARRYRQHQTGKGAKA
                     LRGKGELTLAFAAQVGDRSLALRIEYRIKQLTKRQKERLVTEREAFEALLSSLQTPVL
                     KND"
     gene            complement(16431..16934)
                     /locus_tag="OPY25_000188"
     CDS             complement(16431..16934)
                     /locus_tag="OPY25_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCS0925915.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVVGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHYDLHCRWPGTESAFQVHRLAEDALEGVTGLVEY
                     HDHFNRF"
     gene            complement(16928..17452)
                     /locus_tag="OPY25_000189"
     CDS             complement(16928..17452)
                     /locus_tag="OPY25_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HCS0925916.1"
                     /translation="MLDKLRSRLVHAGPSLMSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LADGELEFLEGRWLSIHVRDIDLKWYTTVENEKLIVSQQADADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRIMLLQLADFVEAGMK
                     NSPETKQTSVGEPC"
     gene            17669..18664
                     /locus_tag="OPY25_000190"
     CDS             17669..18664
                     /locus_tag="OPY25_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCS0925917.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAIRFYHRNFDVHRVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMAEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNDVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKAAPQNFVPQRDWMETLGAMSEGTQTTLGAYHRKWQ"
     gene            18655..19551
                     /locus_tag="OPY25_000191"
     CDS             18655..19551
                     /locus_tag="OPY25_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462188.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCS0925918.1"
                     /translation="MAVRGAMKYSLGPVLYYWPKETLEDFYQQAAKSSADIIYLGEAV
                     CSKRRATKVGDWLEMAKSLAASGKQVALSTLALVQASSELSELKRYVDNGDFLLEASD
                     LGVVNLCAERKLPFVAGHALNCYNAVTLRRLLKEGMVRWCMPVELSRDWLVNLLNQCD
                     ELGIRNQFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRDVLSQENQ
                     QVFVLNGIQTMSGYVYNLGNELTSMQGLVDIVRLSPLGTETFAMLDAFRANENGGAPL
                     PLAAHSDCNGYWKRLAGLELQA"
     gene            19729..20736
                     /locus_tag="OPY25_000192"
     CDS             19729..20736
                     /locus_tag="OPY25_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HCS0925919.1"
                     /translation="MTDKTIPFSVLDLAPIPEGSSAKEAFTHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQPTMRALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPIWLLGSSLYSAQLAAQLGLPFAFASHFTPDMLFQALHLYRTQFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIENMETFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLVSILRETQADEIMVNGQIFDHQARLHSFDLAMDVKQELL
                     G"
     gene            complement(20827..22071)
                     /gene="mtr"
                     /locus_tag="OPY25_000193"
     CDS             complement(20827..22071)
                     /gene="mtr"
                     /locus_tag="OPY25_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HCS0925920.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALVFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFAFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPTTLFNVAESHASYTPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPRTIVKCLIYGTLLALALYSVWLLGTMGNIPRPEFIGIAQKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAMGRFKTALLTFLPPM
                     IGGLLYPNGFLYAIGYAGLAATIWAAIVPALLARKSRERFGSPKFRVWGGKPMIALIL
                     VFGVGNAVIHILSSFNLLPVYQ"
     gene            complement(22225..24114)
                     /gene="deaD"
                     /locus_tag="OPY25_000194"
     CDS             complement(22225..24114)
                     /gene="deaD"
                     /locus_tag="OPY25_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HCS0925921.1"
                     /translation="MAEFETTFADLGLKAPILEALTDLGYEKPSPIQAECIPHLLGGR
                     DVLGMAQTGSGKTAAFSLPLLNNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLAKIQPSAEGEELDLETLAAALLKMAQGERPLILPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREERPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAVPH
                     AGGERRGGGRSFSGERREGGRNFSGERREGGRGDGRRFSGERRESRGPRRDDSTGRRR
                     FGGDA"
     gene            complement(24107..24187)
                     /gene="yrbN"
                     /locus_tag="OPY25_000195"
     CDS             complement(24107..24187)
                     /gene="yrbN"
                     /locus_tag="OPY25_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HCS0925922.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(24293..25177)
                     /gene="nlpI"
                     /locus_tag="OPY25_000196"
     CDS             complement(24293..25177)
                     /gene="nlpI"
                     /locus_tag="OPY25_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HCS0925923.1"
                     /translation="MKPFLRWCFVATALTLAGCSNSAWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPYRSLWLYLVEQKLNEKQAKEALKARFEKSDKEQWGWNIVEFYLGDISEATLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(25287..27422)
                     /gene="pnp"
                     /locus_tag="OPY25_000197"
     CDS             complement(25287..27422)
                     /gene="pnp"
                     /locus_tag="OPY25_000197"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCS0925924.1"
                     /translation="MLNPIVREFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQA
                     INDLVKEAGKPRWDWQPEAVNDALNARVAALAESRLSDAYRITDKQERYAQVDVIKSE
                     TIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKISTDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRI
                     YNSKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRVRLSIKEATEQSQPAAAPEAPASEQAE"
     gene            complement(27664..27933)
                     /gene="rpsO"
                     /locus_tag="OPY25_000198"
     CDS             complement(27664..27933)
                     /gene="rpsO"
                     /locus_tag="OPY25_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCS0925925.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR"
     gene            complement(28084..29028)
                     /gene="truB"
                     /locus_tag="OPY25_000199"
     CDS             complement(28084..29028)
                     /gene="truB"
                     /locus_tag="OPY25_000199"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCS0925926.1"
                     /translation="MSRPRRRGRDIHGVLLLDKPQGMSSNDVLQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVQERPVT
                     FSAEQLASALETFRGDIEQIPSMYSALKYQGRKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEVHCSKGTYIRTIIDDLGEKLGCGAHVTYLRRLTVSKYPVDRMVTLEH
                     LQTLVAQAEQQGVPAAQLLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTTGAP
                     LKGLVRVTEGEDDKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(29028..29429)
                     /gene="rbfA"
                     /locus_tag="OPY25_000200"
     CDS             complement(29028..29429)
                     /gene="rbfA"
                     /locus_tag="OPY25_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCS0925927.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRVGMMTTVSGVEMS
                     RDLAYAKVFVTFLNDQDEAAVKNGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTNVVKHDEERRVNPDDSKED"
     gene            complement(29650..32328)
                     /gene="infB"
                     /locus_tag="OPY25_000201"
     CDS             complement(29650..32328)
                     /gene="infB"
                     /locus_tag="OPY25_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCS0925928.1"
                     /translation="MTDLTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQT
                     LLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAER
                     LAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVS
                     NQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWT
                     ATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKAD
                     REEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQV
                     IKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPR
                     APVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGH
                     AAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEAD
                     PDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGM
                     ASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGP
                     SIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFVN
                     MTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAA
                     SNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIG
                     LAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNE
                     VRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA"
     gene            complement(32353..33855)
                     /gene="nusA"
                     /locus_tag="OPY25_000202"
     CDS             complement(32353..33855)
                     /gene="nusA"
                     /locus_tag="OPY25_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCS0925929.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVEIDRKSGDFDTFRRWLIVEEVTMPTKEITLEAARFEDESLNVGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFRDQEGEIVTGVVKKVNRDNISLEIKSEGMA
                     GNAEAVILREDMLPRENFRPGDRIRGVLYAVRPEARGAQLFVTRSKPEMLIELFRIEV
                     PEIGEEVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERI
                     DIVLWDDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVHLAS
                     QLSGWELNVMTVDDLQAKHQAEAHAAIEIFTKYLDIDEEFATVLVEEGFSTLEELAYV
                     PMKELLEIDGLDEPTVEALRERAKNALATLAQDQEASLGDNKPADDLLNLEGLDRDMA
                     FKLAARGVCTLEDLADQGIDDLADIEGLTDEKAGELIMAARNICWFGDEA"
     gene            complement(33883..34335)
                     /gene="rimP"
                     /locus_tag="OPY25_000203"
     CDS             complement(33883..34335)
                     /gene="rimP"
                     /locus_tag="OPY25_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCS0925930.1"
                     /translation="MSTLEQKLTEMITAPVEALGYELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPISVAYNLEVSSPGLDRPMFTADHYARFQGEEVALV
                     LRMAVQNRRKWQGIIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(34543..34619)
                     /locus_tag="OPY25_000204"
     tRNA            complement(34543..34619)
                     /locus_tag="OPY25_000204"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34583..34585),aa:Met,seq:cat)
     gene            34963..36306
                     /gene="argG"
                     /locus_tag="OPY25_000205"
     CDS             34963..36306
                     /gene="argG"
                     /locus_tag="OPY25_000205"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HCS0925931.1"
                     /translation="MTTILKHLPAGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEDDYDTIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEFLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHSHGRQLGKLLYQG
                     RWFDSQALMLRDGLQRWVASQITGEVTLELRRGNDYSILNTVSDNLTYKAERLTMEKG
                     ESVFSPDDRIGQLTMRNLDITDTREKLFGYAKAGLLTASSATGLPQVENLENKAK"
     gene            complement(36504..36590)
                     /locus_tag="OPY25_000206"
     tRNA            complement(36504..36590)
                     /locus_tag="OPY25_000206"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36554..36556),aa:Leu,seq:gag)
     gene            complement(36604..36936)
                     /gene="secG"
                     /locus_tag="OPY25_000207"
     CDS             complement(36604..36936)
                     /gene="secG"
                     /locus_tag="OPY25_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCS0925932.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTAVLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     QPTSDIPR"
     gene            complement(37159..38496)
                     /gene="glmM"
                     /locus_tag="OPY25_000208"
     CDS             complement(37159..38496)
                     /gene="glmM"
                     /locus_tag="OPY25_000208"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCS0925933.1"
                     /translation="MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIE
                     FCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVG
                     ATDVRALQARVLAEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENEAVK
                     AVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV"
     gene            complement(38489..39337)
                     /gene="folP"
                     /locus_tag="OPY25_000209"
     CDS             complement(38489..39337)
                     /gene="folP"
                     /locus_tag="OPY25_000209"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HCS0925934.1"
                     /translation="MKLFAQGATLDLTHPHVMGILNVTPDSFSDGGAHNTLIEAVKHA
                     NLMVNTGATIIDVGGESTRPGAAEVSVEEELDRVIPVLEAIAQRFEVWISVDTSKPEV
                     IREAARAGAHIINDVRSLSEPGALEAAAETGLPVSLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEKAGIAKEKLLLDPGFGFGKNLSHNYTLLARLGEFHHFNLPLLVGM
                     SRKTMVGQLLNVGPSDRLNGSLACAVIAAMQGAQIIRVHDVKETVEAMRVVEATLSAK
                     GNKRYE"
     gene            complement(39442..41376)
                     /gene="ftsH"
                     /locus_tag="OPY25_000210"
     CDS             complement(39442..41376)
                     /gene="ftsH"
                     /locus_tag="OPY25_000210"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCS0925935.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQD
                     QVREARINGREINVTKKDSNRYTTYIPINDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLATDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGVEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQILTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARREVRPPAGWEDPNGTNNSDSNGTPQAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(41480..42106)
                     /gene="rlmE"
                     /locus_tag="OPY25_000211"
     CDS             complement(41480..42106)
                     /gene="rlmE"
                     /locus_tag="OPY25_000211"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HCS0925936.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALDMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK"
     gene            42233..42526
                     /gene="yhbY"
                     /locus_tag="OPY25_000212"
     CDS             42233..42526
                     /gene="yhbY"
                     /locus_tag="OPY25_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCS0925937.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVMLGNNGLTEGVLAEIEQALEHH
                     ELIKVKIASEDRETKTLIVDAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(42682..43158)
                     /gene="greA"
                     /locus_tag="OPY25_000213"
     CDS             complement(42682..43158)
                     /gene="greA"
                     /locus_tag="OPY25_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCS0925938.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDTDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEQDDVVVIKTPGGDVEYEVLKVEYL"
     gene            43406..44839
                     /gene="dacB"
                     /locus_tag="OPY25_000214"
     CDS             43406..44839
                     /gene="dacB"
                     /locus_tag="OPY25_000214"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HCS0925939.1"
                     /translation="MRFSRFIIGLTTSIAFSVQAANIDEYIKQLPAGANLALMVQKIG
                     APAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVDNGILKGDLI
                     ARFGGDPTLRRQDIRNMVATLKKSGVTQIDGNVLIDTSIFASHDKAPGWPWNDLTQCF
                     SAPPAAAIVDRNCFSVSLYSAQKPNDLAFIRVASYYPVTMFSQVRTLPRGSADAQYCE
                     LDVVPGDLNRYTLTGCLPQRADPLPLAFAIQDGASYAGAILKQELKEAGITYRGTLLR
                     QTQVNEPGTIVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHVRFNVPGTWRAGSD
                     AVRQILRQQAGIDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     PPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(44970..46142)
                     /gene="cgtA"
                     /locus_tag="OPY25_000215"
     CDS             complement(44970..46142)
                     /gene="cgtA"
                     /locus_tag="OPY25_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HCS0925940.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRDLLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDSEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGSDPVENARIIIGELEKYSQDLAAK
                     PRWLVFNKIDLMDKSEAEEKAKAIAEALGWEGKYYLISAASQLGVKDLCWDVMTFIIE
                     NPIAQAEEAKQPEKVEFMWDDYHRQQLAEVEEDADDDWDDDWDEDDEEGVEFIYKR"
     gene            complement(46158..47123)
                     /locus_tag="OPY25_000216"
     CDS             complement(46158..47123)
                     /locus_tag="OPY25_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0925941.1"
                     /translation="MKQQAGIGILLALTTAMCWGALPIAMKQVLEVMEPSTIVFYRFL
                     MASIGLGAILAVKRKLPPLRIFRKPRWLVLLAIATCGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRGTQVIGALMLLSGLVMFFNTSLIEIFTRLTDYTWG
                     VIFGVGAAMVWVSYGVAQKVLLRRLASQQILFLLYTLCTIALLPLAKPMVIAQLSDWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFILLFSDLLSMAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHETVVSQPRSGE"
     gene            complement(47253..47510)
                     /gene="rpmA"
                     /locus_tag="OPY25_000217"
     CDS             complement(47253..47510)
                     /gene="rpmA"
                     /locus_tag="OPY25_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCS0925942.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTK
                     FHAGTNVGCGRDHTLFAKADGKVKFEVKGPKNRKYISIVAE"
     gene            complement(47530..47841)
                     /gene="rplU"
                     /locus_tag="OPY25_000218"
     CDS             complement(47530..47841)
                     /gene="rplU"
                     /locus_tag="OPY25_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCS0925943.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            48100..49071
                     /gene="ispB"
                     /locus_tag="OPY25_000219"
     CDS             48100..49071
                     /gene="ispB"
                     /locus_tag="OPY25_000219"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HCS0925944.1"
                     /translation="MNLEKINELTAQDMAGVNATILEQLNSDVQLINQLGYYIISGGG
                     KRIRPMIAVLAARAVGYQGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEQEKGLQDYGRYLGTAFQLIDDLLDYSA
                     DGEHLGKNVGDDLNEGKPTLPLLHAMRHGTPEQSAMIRTAIEQGNGRHLLEPVLEAMT
                     TCGSLEWTRQRAEEEADKAISALQILPDTPWREALIGLAHIAVQRDR"
     gene            49304..49591
                     /gene="sfsB"
                     /locus_tag="OPY25_000220"
     CDS             49304..49591
                     /gene="sfsB"
                     /locus_tag="OPY25_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HCS0925945.1"
                     /translation="MESKLIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALTR
                     PWPKGELIIAKALGTEPWVIWPSRYHDPRTHEFIDRTRLMRARNKDKQNVE"
     gene            complement(49650..50909)
                     /gene="murA"
                     /locus_tag="OPY25_000221"
     CDS             complement(49650..50909)
                     /gene="murA"
                     /locus_tag="OPY25_000221"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCS0925946.1"
                     /translation="MDKFRVQGPTTLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDASQVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHITGLEQLGATIKLEEGYVKASVEGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLVTLGAKIAGQGTDRITIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKILCRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGARAEIESNTVICHGVETLSGAQVMATDLRASASLVLAGCIAEGTTIVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(50963..51217)
                     /gene="ibaG"
                     /locus_tag="OPY25_000222"
     CDS             complement(50963..51217)
                     /gene="ibaG"
                     /locus_tag="OPY25_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HCS0925947.1"
                     /translation="MENHEIQSVLMNALSLQEVHVSGDGSHFQVIAVGEMFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(51405..51701)
                     /gene="mlaB"
                     /locus_tag="OPY25_000223"
     CDS             complement(51405..51701)
                     /gene="mlaB"
                     /locus_tag="OPY25_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HCS0925948.1"
                     /translation="MTPQLTWTREADTLVLAGELDQDVLAPLWDARVEAMNGVTRIDL
                     SQISRVDTGGLALLAHLVNQAKKQGNAVSLSGVNDKVYALAQLYNLPEDVLPRM"
     gene            complement(51701..52336)
                     /gene="mlaC"
                     /locus_tag="OPY25_000224"
     CDS             complement(51701..52336)
                     /gene="mlaC"
                     /locus_tag="OPY25_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HCS0925949.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQSNPYKLMNEAAQKTFDRLKN
                     EQPKIRANPDYLRDVVDQELLPYVQVKYAGALVLGRYYKEATPAQREAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDATIVPIRVTIIDPNGRPPVRLDFQWRKNTQTGN
                     WQAYDMIAEGVSMITTKQNEWSDLLRTKGIDGLTAQLKSISQQKITLDEKQ"
     gene            complement(52355..52906)
                     /gene="mlaD"
                     /locus_tag="OPY25_000225"
     CDS             complement(52355..52906)
                     /gene="mlaD"
                     /locus_tag="OPY25_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HCS0925950.1"
                     /translation="MQTKKNEIWVGVFLLVALLAALFVCLKAANVTSMRTEPTYKVYA
                     TFDNIGGLKVRSPVRIGGVVVGRVEDISLDPKTYLPRVTLDIEERYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTSILKDGSTIQDTKSAMVLEDMIGQFLYNSKGDDNK
                     NSGDAPAATEGHTEATTPAGETK"
     gene            complement(52911..53693)
                     /gene="mlaE"
                     /locus_tag="OPY25_000226"
     CDS             complement(52911..53693)
                     /gene="mlaE"
                     /locus_tag="OPY25_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HCS0925951.1"
                     /translation="MLLNALAALGHSGIKTVRTFGRAGLMLFNAIIGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIIVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTI
                     IFVAVGIWGGSLVGVSWKGIDAGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWIAL
                     FNGYDAIPTSAGISRATTRTVVHASLAVLGLDFVLTALMFGN"
     gene            complement(53701..54513)
                     /gene="mlaF"
                     /locus_tag="OPY25_000227"
     CDS             complement(53701..54513)
                     /gene="mlaF"
                     /locus_tag="OPY25_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HCS0925952.1"
                     /translation="MGQSAANLVDMRDVSFCRGERCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIPPDKGEILFDGENVPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTNLPAPLLKSVVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIM
                     ADKKIVAHGSAQALQENTDPRVRQFLDGIADGPVPFRYPAGDYHLDLLETGS"
     gene            54726..55703
                     /locus_tag="OPY25_000228"
     CDS             54726..55703
                     /locus_tag="OPY25_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HCS0925953.1"
                     /translation="MLLAMALLIIGLLLVAYGADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSVAASLHGQLDLAVGAALGSNITNILLILGLAALVRPFTVHSDVLR
                     RELPLMLFVSVVAGSVLHDGQLSRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTR
                     EQLAELPREDGLPVAFLWLGIALVIMPMATRMVIDNATVLANYFAMSELTLGLTVIAV
                     GTSLPELATAIAGVRKGENDIAVGNLIGANIFNLAIVLGLPALIAPGEINPLAFGRDY
                     SVMLLVSVVFALLCWRHPRQIGRGAGILLTGGFIVWLAMLYWLSPLLVG"
     gene            55717..56703
                     /gene="kdsD"
                     /locus_tag="OPY25_000229"
     CDS             55717..56703
                     /gene="kdsD"
                     /locus_tag="OPY25_000229"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HCS0925954.1"
                     /translation="MSHLALQPGFDFQQAGKEVLEIEREGLAELDQYINQHFTLACEK
                     MFNCTGKVVVMGMGKSGHIGRKMAATFASTGTSSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEIAALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVPKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVSDIMHTGDEIPH
                     VNKHATLRDALLEITRKNLGMTVICDESMKIDGIFTDGDLRRMFDMGGDMRQLGIAEV
                     MTPGGIRVRPGILAVDALNLMQSRHITSVLVADGDQLLGVLHMHDLLRAGVV"
     gene            56724..57290
                     /gene="kdsC"
                     /locus_tag="OPY25_000230"
     CDS             56724..57290
                     /gene="kdsC"
                     /locus_tag="OPY25_000230"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HCS0925955.1"
                     /translation="MSKAGASLATCYGPVSTHVMTKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSNIEVAIITGRKAKLVEDRCATLGIVHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTHIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            57287..57862
                     /gene="lptC"
                     /locus_tag="OPY25_000231"
     CDS             57287..57862
                     /gene="lptC"
                     /locus_tag="OPY25_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HCS0925956.1"
                     /translation="MSKTRRWVIILLSLAILVLIGINLADKDDPAAVMVNSNDPTYKS
                     EHTDTVVYSPEGALSYRLIAQHVEYFSDQAVSWFTQPVLTTFDKDKVPTWSIKADKAK
                     LTNDRMLYLYGHVEVNALVPDAQLRRITTDNAQINLVTQDVTSNDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            57831..58385
                     /gene="lptA"
                     /locus_tag="OPY25_000232"
     CDS             57831..58385
                     /gene="lptA"
                     /locus_tag="OPY25_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HCS0925957.1"
                     /translation="MKFKTNKLSLNLMLAGSLLAASIPAFAVTGDTEQPIHIDSDQQS
                     LDMQGNVVTFTGNVVMTQGTIKINADKVVVTRPGGEQGKEVIDGYGNPATFYQMQDNG
                     KPVKGHASHMHYELAKDFVVLTGNAYLEQLDSNITGDKITYLVKEQKMQAFSEKGKRV
                     TTVLVPSQLQDKNKGQTPAQKKSN"
     gene            58392..59117
                     /gene="lptB"
                     /locus_tag="OPY25_000233"
     CDS             58392..59117
                     /gene="lptB"
                     /locus_tag="OPY25_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HCS0925958.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYLPQEASIFRRLSVFDNLMAV
                     LQIRDDLTAEQREDRANELMEEFHIEHLRDSMGQALSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            59165..60598
                     /gene="rpoN"
                     /locus_tag="OPY25_000234"
     CDS             59165..60598
                     /gene="rpoN"
                     /locus_tag="OPY25_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCS0925959.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALENN
                     PLLEQTDLHDEIDTQQPQDDDPLDTADALEQKEMPEELPLDASWDEIYTAGTPSGPSG
                     DYIDDELPVYQGETTQSLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVSLDE
                     IRESMGDVEVDLDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKSTPWLEEARL
                     IICDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGRWTVELNSDSIPRLQINQHYAAMCNSARNDADSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            60621..60908
                     /gene="hpf"
                     /locus_tag="OPY25_000235"
     CDS             60621..60908
                     /gene="hpf"
                     /locus_tag="OPY25_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HCS0925960.1"
                     /translation="MQLNITGHNVEITEALREFVTTKFAKLEQYFERINQVYVVLKVE
                     KVTHISDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQY"
     gene            61026..61517
                     /gene="ptsN"
                     /locus_tag="OPY25_000236"
     CDS             61026..61517
                     /gene="ptsN"
                     /locus_tag="OPY25_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HCS0925961.1"
                     /translation="MINNDTTLQLSSVLNQECTRSGVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAALNDEELYQIITDTEGEQ
                     NEA"
     gene            61563..62417
                     /gene="rapZ"
                     /locus_tag="OPY25_000237"
     CDS             61563..62417
                     /gene="rapZ"
                     /locus_tag="OPY25_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCS0925962.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADRQISAAVSIDVRNIPESPEIFEQAMNNLPGAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKT"
     gene            62414..62686
                     /gene="npr"
                     /locus_tag="OPY25_000238"
     CDS             62414..62686
                     /gene="npr"
                     /locus_tag="OPY25_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HCS0925963.1"
                     /translation="MTVKQTVEVTNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEIEATGPQEVEALAAVIALFNSGFDED"
BASE COUNT        14653 a        17423 c        16103 g        14574 t
ORIGIN      
        1 atttccagta aaaatatgct ccagaaggcc cagcatgcag gctatgccgt gccagccttt
       61 aacatccata acctagaaac cttgcaggtg gtggtagaaa ccgccgcaga aatgcgctca
      121 ccgctgatcg ttgccggaac accaggcacg tttagctatg ccggaatggg taacattgtg
      181 gcgatcgcgg gcgatctggc tcgtgaatac aatctgccac tggccattca tctggatcat
      241 catgaatcgt tagccgatat tgaaagcaaa gttatggcag ggatccgttc agtcatgatc
      301 gatggttccc actttccctt tgaagagaat gtggcgctgg tgaaaagcgt ggtcgatttt
      361 tgccatcgct acgacaccag cgtggaggca gaactgggcc gccttggtgg gatcgaagat
      421 gatttagtgg tagacagcaa agatgccctt tacaccaatc cacagcaagc acgtgagttt
      481 gtggcgcgca ccggcattga ttcgctggcg gttgctatcg gcacggcaca cggtatgtat
      541 gccgctgaac ctaaacttga ttttgagcga ctggcagaaa tacgcgctct ggtggatatc
      601 cctctggtat tgcatggggc atctggtttg ccggaaagcg atattcgcca ggccatcagc
      661 cttggggtat gcaaagtcaa tgtcgccacc gaactgaaaa tcgccttctc cgacgcctta
      721 aaagagtatt tcctacaaaa cccgaaagcc aatgatcccc gccactatat gcaaccagca
      781 aaacaggcga tgaaagaggt ggtacgcaaa gtaattcatg tttgcggctg tgaagggcaa
      841 ctgtgaggaa tcgcctgtga tctacacgct aacacttaat agcgcgattg atatgaatat
      901 atttagcgat cctttacagc caaatattgt caatcgcact caccacaccg agttttgccc
      961 aaatggtaaa ggggtaaatg ttgcgctggt tctggatcac tttcaaatac ctgcgcatat
     1021 attaggcatt tttggtggtt tcaccgggca ttatattgta gaaagcctgc gtacccgaaa
     1081 aatgccagtc acaccagcat gggtagaaga acccacgcgg attaatattt tcattcatga
     1141 cggcaagcag gaatataaac tggtcaaccc tggctcatat attccagatg aatgtaaaaa
     1201 acaaattatc acgattattt cgcaactgcc cgatgcagaa tatctggtga taagcggcag
     1261 cctgccacaa ggtattgaaa gtcgctttta cgcagaaatt atgcatattt gtcagcaaaa
     1321 aaatatcggc gtaattttag atattagtca tccgtcatta cgtcagttac tggagttcaa
     1381 accgttatta attaaaccaa atgatgaaga ggttaaagca atattcggtt taactgtctc
     1441 tgacgacaat gatgcgaaaa atactctaac cactttacat gcacttggtg cacaaaatgt
     1501 tctgctaacc cttggcgcta aaggaatgta tttctccaat gggattgatt actggttttg
     1561 tagcgcgcca acggttgatt tggtgagctc cgcctgtgca ggcgatgctg cactggccgc
     1621 ctttctcagc cagtggttat ctacaggaga agtggaatat gccttatctc ttgccagtgc
     1681 aacaggagct gatgtcgcaa gttctgccgg actaggccaa cttgcggcaa tagaaacctt
     1741 actttcgcaa atccacgtca gaaagctgta ggttaaatta caatataagt tctgcttatg
     1801 aaaaagatca ttgcagtgac cggctgccct accggtattg cgcatacatt tatggctgaa
     1861 gaagccttaa aaaatgccgc gaaaaaatta tctgttgaaa taaaagttga aaccaatggt
     1921 gccagcggtg ttgaaaatgc cattcaacct gctgatctgg tagatattgc cggagtcatt
     1981 attgcggcgg ataaagatgt cttacctgat cgctttaatg gtttaccggt tattgaagta
     2041 ccggtaaaag aagcaatcca tcatcctgcg gagctgatta acaaagttat taatggtgaa
     2101 gccccaatac gtaaaggcga atcaaccacc agcacggaaa ttatcgaaaa agaatcactg
     2161 gggcgacaaa tttataagca cctgatgagt ggtgtttcaa atatgctacc ttttgtagtt
     2221 gccggaggca tattaattgc ggtgtcgctt ttatggggga tttattccgc tgatcctaat
     2281 tcagctgaat acaatgcaac cgccgcaatg ctaatgaaaa tcggtcagca agccttttcg
     2341 attatggttc cggtctttac cgcttatatt gcattctcta tttctggcag accagggatg
     2401 gtggctgggt ttgtcggcgg cttactggca aatactaccg gagcaggatt tctcggtggg
     2461 ataattgccg gattcgccgc cggttacctg atgttatggg taaagaatcg actcgaaggc
     2521 ttaccgcgtc agtatgaagg cctgaaatcg atttttatta tgccgctcat tggcgtactg
     2581 gttattggcg tgttgatgtc gctgcttggg caacctgtcg cagctatcaa taatagcatg
     2641 atgaactggc tggcatcgct acaggaagcg aatccaatat tgctgggtat tgtggtgggt
     2701 gcaatgtgct cttttgactt tggcggcccg gtaaacaaag ccgcttatgt caccggcacg
     2761 cttttactgg gccagggcaa cttctacttt atggctggtg tgtctgccgc atgtattact
     2821 ccaccactgg taattgctct ggcgaccacc ttctttccaa aaggttttag cgaggaagaa
     2881 cgtgccgcag gcatggttaa ctatatcctc ggttgtacac acatcactga aggcgcgatt
     2941 cctttcgcag cgaaagatcc tttgcgtgtc atcccgatga tgatgattgc ttccagcatt
     3001 tccgcagtac ttagctacag cttgcgtatt caggttccgg ctcctcacgg cggcttctta
     3061 attttacctt tggtgagtca gccgctggcc tgggtgttat gtatccttgc gggatctgca
     3121 tgtggtgcga tgatgcttgg cctatggaga ttgtgggctg tgcgcaaaaa ttcagtcaac
     3181 acaactcctg tagcaaaggc tggaggtcag aatgcagctc tgtgaacacg atatttttat
     3241 cagcgatgag cgcctcgata aagtcaccgc tctgcaccgc gtggtggaaa agttatctgc
     3301 ggctggcaat accacgcctg actatttacg cggcatgttg gatcgcgaag cacagatttc
     3361 cacttatctg ggaaatggaa tcgcgatccc acacggtacg ccagaatctc gcgatgcggt
     3421 attacaaacc ggtgtaaagg taatcgtttt tcgccacggc gttgactggg gtgacggcaa
     3481 taccgcgtat ctggtcaccg gaattgccgc gcgctccaat gaacatcttg agattttgcg
     3541 ccaactgact cgcgtgctca gcgatgacgc tattctgcaa gcactggcta aagccgaatc
     3601 ccccagtcag gttttagcgc tactgactgg ctcgacgacc aatacgccag cagccatgga
     3661 gttgcacgag ggtgagcagg caacatttgt catccataat ccgcatggtt tacatgccag
     3721 acccagtgcg gtactggtga agtttatcaa acagtttcaa agccacatta cggtagaaaa
     3781 tctggataac gcctccggcc cggtggacgg aaaaaacctg atgcgagtgg tgtcgctcgg
     3841 cgcgaaaaag gggcatcgct tgttgttccg ggcgcagggc gaagatgcac agcaggcact
     3901 acgtgaaatc ggggagctta tcgcctctgg tgcaggcgag atgatcaccg ttcccgttac
     3961 cccaccacca gaagtcatgc agccaaagcg cagttggcta tctcgattgt ttaattagcc
     4021 ttcatttgtt cctccgtgcc cgctccggcg ggtacggttt ttcatgacaa agtgaagtta
     4081 cagacattac acaccatttc gttaccttac attttctttc gcaactttca tttatcagat
     4141 caaaatcaca aaacaacatt acgaaagcct ataaattctt tcgaagaata aaaacgaaag
     4201 aactcggaga taaaagtgaa agaaataatt gctcgtcata aagcaggaga acatctgggc
     4261 atctgttcag tttgttctgc tcatcccctg gttatcgaat cagctctgct tttcgatctc
     4321 aatactgaca acaaggtatt gattgaagcc acatccaatc aggtgaatca gtttggcggt
     4381 tataccggaa tgaaaccggc tgattttcgt gattttattt atggcattgc tcaggaagtg
     4441 ggatttccac gtgagcggtt gattcttggt ggcgatcatt tagggcctaa ctgctggcag
     4501 aacgaaccgg cagcggcggc aatggaaaag tcggttgagt taataaaagc gtatgtcgcc
     4561 gctggtttta gcaaaattca cctggacgcg tcgatgtcct gcgctgacga cccgacaccg
     4621 ttggatccga tggtcgttgc acgccgtgcc gccgtgcttt gtaaagcagc agaagagacc
     4681 gcaaacgaag aacaaaaatg ccatctgact tatgtcatcg gcacggaagt gcccgttcct
     4741 ggcggtgaag ccagtaccat cggcagcgtt catgtcaccc gcgaggtcga tgctgcccgt
     4801 acgctggaaa ctcaccaaat cgcgtttcgt gaatcaggtc tggaagaagc actgtcacgc
     4861 gtgatcgcca ttgtggtgca accgggcgtt gaatttgatc atacccagat tattcattat
     4921 cagccgcagg cggcacaggc gctctccgca tggatcaaag aaacgccgat ggtctatgaa
     4981 gcgcattcga ctgattacca aactcgccag gcctaccgcg ccctcgttcg cgatcattac
     5041 gccattctga aggtcggccc tgcactcact ttcgccctgc gcgaagccat tttcgcactt
     5101 gcgcaaatgg aaaacgagct gatctccccg gaacaacgta gccgcgtgat ggaagttatc
     5161 gatgaagtga tgctaaacga gccaggctac tggaaaaagt actaccgccc cacctagagc
     5221 caggcgatgg tcgacatcca ctttagtttg tctgaccgta ttcgctatta ctggccgcac
     5281 ccgcgtattc gtcaaagcgt agagaagtta atcgccaatc tgaataacgt cacattgccg
     5341 ctgggattaa ttagccagtt tatgcccgta cagtttgaac gcctgtctga gggcgtgctc
     5401 acccccacgc cgcataacct gattattgac aaaattcagg atgttctgcg cgcttatcgc
     5461 ttcggttgca cgccggatgt cgcctgaata gtggagaatt tatgagccaa ttatttgtcc
     5521 gaaccggaat cacattcgac tcgagccaac aggcgctggc gcacattggc aaagagatgc
     5581 tggcgaaagg cgtggtacat gatagttatc cgcaggcact ggtggaacgt gaagcgtcct
     5641 ttcccaccgg cattgcgctg gagcgccacg ccgtcgctat ccctcattgc gaggcagttc
     5701 atgcgaaatc acccgctatc tatctgattc gtccagataa gccggtcatg tttcaacagg
     5761 cggatgatga cgaagagatt gccgtttcgt taatcatcgc cttaatcgtt gaaaacccgg
     5821 cggcacagct aaaacttctg cgccgtctgt tcggggcatt acaaatcccg gacaccatag
     5881 aagccttact gagcgccccg gatgccgaac tggcgtcgtg ctttgagcac aaagtcctta
     5941 cggctgagca gtgcgtccag gtttaataat aaattgataa taatgaggaa taccctatga
     6001 aacgtaaagt aattgtggcc tgtggcggtg cggttgcaac ctcaacgatg gctgcggaag
     6061 aaattaaaga gctatgtgat gccaaccata ttgagctcga cttagtgcaa tgccgggtca
     6121 ccgaaatcga aacctatatg gacggcgccg atcttatctg taccactgcc agggtcgatc
     6181 gcgcctttgg cgatattccc gtcgttcacg gtatgccttt tgtttccggc gtgggtattg
     6241 aagcattaca gcaaaaaatt ctgtccattc tcatggggta acgtatgttt agcgaaataa
     6301 tgcgttatat cctcgactta ggcccaacgg tgatgttgcc tctggtgatc atcgtgttct
     6361 ctaaactgct gggaatgaag cttggggatt gttttaaatc gggtttgcat attggtatcg
     6421 gcttcgtggg tattggtctg gtcatcggcc tgatgctgga ttctatcggc cccgcggcga
     6481 aagccatggc ggaacatttc caaatcaatc tccacgttat tgacgtcggc tggccgggtt
     6541 catcgcccat gacctgggcg tcacaaatcg cgctggtcgc gatccctgtc gccatcgggg
     6601 ttaacgtcct gatgctggtg acccgcatga cccgcgtggt gaatgtcgat atctggaata
     6661 tctggcacat gaccttcacg ggcgccatgc tgcatctggc gaccggttca tactggctgg
     6721 ggattctggg cgttgtggtt catgccgcct ttgtctacaa actgggggac tggtttgcca
     6781 aagatacccg cgactatttt ggcctcgagg ggattgctat cccacacggc tcatccgcgt
     6841 acctgagccc cgtggcggtg ctcgttgata ccattatcga gaaaattccg ggtctcaatc
     6901 gtattcactt tagcgcagac gatgtccaga aacgcttcgg accgtttggc gagccggtga
     6961 ctgtcggctt cgtgatgggg ctggtgattg gtgtactggc aggctacgac accaaagccg
     7021 ttctgcaact ggcagtcaaa accgcagcgg tgatgctgct tatgccacgc gtcattaaac
     7081 ctattatgga tggcctaacg cctatcgcca aacatgcgcg taaacgtcta caggccaaat
     7141 ttggcgggca ggagttcctg ataggccttg atccagcgct actgctcggt catacctctg
     7201 ttgtctccgc gagcctgata ttcattccgc tgaccatcct gattgccgtc ttagtaccgg
     7261 ggaaccaggt gctgccgttc ggcgacctcg ccaccatcgg tttctttatt gcgatggcgg
     7321 ttgcggtaca ccagggcaac ctgttccgca cgctgatttc aggtgtcatt attatgggta
     7381 tcaccctgtg gatagccacg cagacgattg gcctgcatac ccaactggct gccaatgccg
     7441 gagcgctaaa agctggcgca caagtcgcct cgctggatca gggcggttct cccatcacct
     7501 ggctgctgat tcaacttttt acctggcaga atatcgtcgg cttcgccgtc attgccatta
     7561 tctatctggc cggcgtactg ctgacctggc gtcgcgcccg acagtttgtc gcggctgaga
     7621 aagccacggc gctacagcaa agtcaaatcg cctcttaatt ttaggggagc aatcgctccc
     7681 ctcaccttcc tggagaatgt tatgaaatca gtggttattc acgctgaggg agacgtgcgc
     7741 gttgaagaac gtcccttacc acaactgcaa gccgaggacg atgtgttggt caaagtcgtt
     7801 agctcagggc tttgcgggtc ggatatcccg cgtattttcg cgcagggcgc ccattattat
     7861 cctattacgt taggccatga attcagcggc tacgttgaat cctacggcac aggcgtaacg
     7921 gatatgcagc ctggcgatgc cgtcgcttgt gtcccgcttc ttccctgctt tcactgtccg
     7981 caatgcgaac gcggttactt ttctttatgc aaacagtatc agtttgtagg atcgcgcagc
     8041 gaaggcggta atgcggaata tgtggtggtc aaacgggcca atcttttccg cttgccgtct
     8101 gatatgccga ttgaagatgg cgcgtttatc gaaccgatta ccgtgggctt acacgccttt
     8161 catctggcgc agggctgcga ggggaaaaac gtaattatcg tcggggccgg gacaattggc
     8221 ctgctggcct tacagtgcgc gcgggaactg ggcgcgcgaa gcgtaacggc gattgatatc
     8281 aatccgcaga aactggaact ggcgaaagcg ctcggcgcaa cgcatacctg taatagccgg
     8341 gaaatgaccg ccgacgacat ccagaccgcg ttgtccgaca ttcagtttga tcaactggtt
     8401 ctcgaaacgg caggaactcc ccagaccgtc tcgctggcta tcgatatcac cgggccgcgc
     8461 gcgcaactgg cgctggtggg gacgttacat cacgatctca ccctgacgac gcgtacattc
     8521 gggttaattt tgcgtaaaga gctcacgctc ctcggcagtt ggatgaacta ctccgcgcca
     8581 tggccaggag aagaatggga aaccgcagcg cgcctgttgg ctgaaaaacg tcttcaactg
     8641 acccctctca ttgcccatcg cggcgatgcg gaaagctttg cagaagcagt caaagcgctt
     8701 aatggcgcgc ccatgcaggg caaaatctta cttcaacttt cctgatggta cgagccagca
     8761 acctgcgctg gctcacattt cctttcgaaa tttagcgttc acctttcgca atccttcgtt
     8821 taaactagtt acagttaatt atcaggcaaa tcaatatgaa ctcatttgag cgaagaaata
     8881 aaattgtcga cctgattaat acgcaaggca gcgtgctggt gatggacctt tcaaatacct
     8941 ttggtatttc tgaagtgact atccgtgctg acctgcgtct gctggaagag aaaggccttg
     9001 tcacccgttt tcatggcggc gcggcaaaac cgggaagtca tctggcggaa ggcgacaatc
     9061 aggaagtcat tctggaagat cggtatcaac tcgccagcga tccgaaaaag cggattgccc
     9121 aggcggctgc ggcaatggtt gaagaaggaa tgaccatcat tctggatagc gggagcacaa
     9181 cattactaat tgcggaagcg ctcgcgcgaa aaagcaatat tacggtgatc actaacagct
     9241 tgcctgccgc ttttacgcta tcagaaaata aagatctcac gctggtggtt tgcggcggta
     9301 cggtacggca taaaacccac tcaatgcacg gcacgattgc ggaacgatcg ctacacggca
     9361 tcagcgccga tgtcatgttt gtcggggcgg atggcattga tgcgacaaac ggtattacca
     9421 cgtttaacga aggttattcc attagcggcg tcatggcggc ggcggcgcac aaagttatcg
     9481 cggtactgga cgcgaccaaa tttaaccgtc gcggctttaa ccaggtattg ccgatggaca
     9541 agatcgactg tgtgataacc gatgacacca tcagcaaaca ggataaagcg gcattagcga
     9601 aaacaggcgt ggaattaatg atcgtctaaa aaggagtcgg ttatgcattg ctgatcgcga
     9661 gagtaagccc aaaggaaagg tccggcccgc tatcaccgcc caatgccccc atcactttac
     9721 ccacatcaat cacctgattg agtattaacg tgatggcgat aaaaggcggt tcccgggcgc
     9781 tcgcttttac tcttcctgct gcgccagcgc atacttatac agcgcatttt tcttcacgcc
     9841 gtgaatttct gctgccagcg ccgccgcttt tttcagcggc agctctgcct gtagcagcgc
     9901 cagcgtgcgc agcgcgtcgg cgggcaggtc gtcttcttgc gctttatgcc cttcgacaat
     9961 cagcaccatt tcgcctttgc gacggttttc atcttctttg acccacgcca gcagctcgcc
    10021 gaccggcgcg ccgtgaatgg tttcccaggt tttggtcagc tcacgcgcca gcaccacgta
    10081 acgggattcg ccccacacgg ccaccatatc ttccaggcta tccaacagac gatgggtgga
    10141 ctcataaaaa atcagcgttc gtggctccgc ttcaatggct tttagcgcat cacggcggcc
    10201 ttttgatttg gcaggcagga agccttcata acaaaaacga tctgatggta aacctgcggc
    10261 gcttaatgca gtgatagcag cacacggccc tggtagcggc accacgcgaa tccccgcttc
    10321 acggcaggta cgtaccaggt gatagccggg gtcattaatt agcggcgttc cggcatcgga
    10381 aaccagagca atgttctgcc cctctttcag cttcgcgacc agcgtttccg ctttttgttg
    10441 ttcgttatgg tcgtgcagcg caaacaaccg ggcattaatc ccaaaatgtt gcagcaataa
    10501 accggtgtga cgagtgtctt cagcggcaat taaatcaacg gcttgtaaaa cttccagcgc
    10561 gcgttgggta atatcagcca aattcccgat aggagtaggt acaataaaga gttggccctg
    10621 agaattatcc gccgattcgt tttgtttcat tgtgtcgtcc gtattgccga tttaatattg
    10681 agcattgcgt aaaaaaatat cactggatac agtatggtac cctcaacatt ttctcgtttg
    10741 aacgccgcgc gcgcgctgcc tgtcgtcctg gctgcgctac ttttcgccgg gtgcggcacc
    10801 caggcgccag atcaaagcgc agcctatatg cagggttcag cgcaagctga ttccgccttt
    10861 tacctgcatc agatgcagca aagcgcagat gatagcaaga ccaactggca attactcgcc
    10921 attcatgcac tgctgaaaga aggaaaaagc cagcaggccg tcgagttgtt caatcaaccc
    10981 ccgcaaaatc tgaacgatac ccagcgtcgc gaacaatctt tattagcggt agagatcaaa
    11041 ctggcgcaga aagatgtggc aggcgcgcag gccttgctgg ataaactaaa acccgccgac
    11101 tttgcgccac atcagcaagc gcgttactgg caggcgcaga tcgttgccag ccagggacgc
    11161 ccgtcgctta ccctgttgcg ggcgttaatc gcccaggaac cgctactggc ggcgaaagag
    11221 aaacaaaaaa atatcgacgc cacctggcag gcgctctccg ccatgacgcc ggatcaggcc
    11281 aggacgttag ttatcaacgc cgatgaaaat gtgcttcagg gctggctgga tctgcaacgc
    11341 gtctggtttg acaaccgcaa cgatccagac atgctgaaag ccgggatcgc cgactggcaa
    11401 aaacgctacc cgcaaaatcc gggggcgaaa atgctgccga cgcagctcgt caatgtacaa
    11461 cgttttaaac cagcttccac cagcaaaatc gctctgctgc tgccgctgaa cggtcaggct
    11521 gccgtgtttg gccgtaccat ccagcaaggt ttcgaagccg cgaaaaacct cggcacccag
    11581 gcggtggaaa tgcagcctgt cgccgcgcct gacgcgccgg tcgaaccaag cgtggaggag
    11641 acgcaaccac aaatgaccaa cggcgtcgcc agtccgtcgc aggcctcggt gagagatctg
    11701 actgatgacg ctccatccca gtctgctacg ccagtcagcg cgccacaaac tccccctgcg
    11761 cagcctgcta cagcaagcgc gccggcggat ccctccgctg aattaaaaat ctacgatacc
    11821 tcttcccagc cgttggatca ggtgctcgct caggttcagc aagacggcgc cagtatcgtg
    11881 gtcgggccgc tgttgaaaaa caatgtggaa gcgctgatga aaagcaacac gccgctcaac
    11941 gtgctggcgc tcaaccagcc ggaaacggta cgtagcttcc ctaatatctg ctatttcgcg
    12001 ctctctccag aagatgaagc ccgtgacgcg gcgcatcata tttatgagca gggcaagcag
    12061 tcgccgctgc tgttgatccc acgcagcgcg cttggcgatc gcgtggcgaa tgccttcacc
    12121 caggagtggc aaaaactggg cggcggcatc gtgttacagc aaaaattcgg ctccgtagcc
    12181 gagctgaaaa tgggcgtgaa cggcggcgcg ggtatcgcgt tgacgggcag tccggtcgcc
    12241 gccagcgtgc ctgcgcagcc gggcgttacc attggcggtc tgaccatccc tgcgccgccg
    12301 accgacgcgc aaatcaccgg cggcggacgc gtagacgcgg tctatattct ggctacgccg
    12361 gaagagattg gctttatcaa accgatgatc gccatgcgta acggcaccca gagcggcgcg
    12421 acgctgtatg ccagctcccg cagcgcgcaa ggcacctccg gccctgactt ccgtctggag
    12481 atggaaggtt tgcaatacag tgaaattccc atgctggcag gcggcaatac gccgttgatg
    12541 cagcaggcgc tgagtgctgt acataacgac tattctctgg cgcggatgta cgccatgggc
    12601 gtggatgcct ggacgctggc gaaccacttt tcgcagatgc gtcaggtgca ggggtttgag
    12661 atcaatggta ataccggcgc attaaccgcc agcccggatt gtgtgattaa caggaagtta
    12721 tcatggctca aataccagca aggggagatt gttcccgcca gctaacacgt aaacaggctg
    12781 gcgacgcgtg ggaagctgcc gcgcgtctct ggctggaaag caaaggactg cggtttatcg
    12841 ccgccaacgt gcgcgagcgc ggcggcgaaa tcgatctgat catgcgcgac ggaaaaacga
    12901 cggtttttgt tgaggttcgc tatcggcgct ccgggcttta tggcggcgcg gcggctagtg
    12961 tgacccgcag caagcaacac aaattattac atactgcccg cttgtggctc gcccgccaga
    13021 atgggagttt tgatactgtg gattgtcggt tcgatgtgtt agccttcacc ggaaatgaga
    13081 ttgagtggtt tcgggatgcg tttaacgacc actcataatt gaagatttta aggattagcg
    13141 tgctcgaaag aatcaaagtt tgctttacag aaagcattca aactcaaatt gctgcggcgg
    13201 aagcgcttcc ggatgccatt tcccgcgccg ccatgacgct ggttcattcc ctgcttaacg
    13261 gcaacaaaat cctctgttgt ggaaacggga cgtccgcggc caacgcacag cattttgctg
    13321 ccagcatgat taaccgcttt gaaacggagc gacccagttt acccgccatt gcactaaata
    13381 ccgataatgt ggtcttaact gcgatcgcta acgatcgcct gcacgatgaa gtttatgcaa
    13441 aacaagtccg ggcgctggga catgcaggcg atgttttatt ggcgatctct acgcgtggta
    13501 atagtcgcga tatcgtaaaa gccgttgaag cagccgtcac acgtgacatg accattgtgg
    13561 cgctaaccgg gtatgacggg ggcgagctgg ccggactatt agggccgcag gatgttgaaa
    13621 ttcgtatccc ttcacaccac agcgcgcgca ttcaggaaat gcatatgctg acggtaaact
    13681 gcctgtgcgg tttgatcgat aacacgcttt ttcctcacca ggatgattaa ggagtacaca
    13741 tgaaggcatt ttcgccgctc gcagtcctta tttctgcgtt gctattgcaa ggttgcgtcg
    13801 ccgccgcggt agtgggtacg gcagccgtcg gcaccaaagc cgcaaccgac ccgcgtagcg
    13861 tgggcaccca ggtggatgac ggaacgctgg aactgcgtgt cagcagcgcg ctgtcgaaag
    13921 atgagcaaat caaaaaagag acgcgcatca atgtcactgc ttatcagggc aaagttttgt
    13981 tagtgggcca gtcgccaaac agcgaactct ccgcacgcgc gaaacagata gcgatgggcg
    14041 ttgaaggcac caccgaggtc tataacgaga ttcgccaggg tcagcctatc ggcctgggga
    14101 ccgcctctaa cgatacctgg atcaccacga aagttcgctc acagctactg accagcgatc
    14161 aggtaaaatc gtcaaatgtg aaagtcacca ccgagaatgg cgaagtgttc ctgctgggcc
    14221 tggtgactga acgtgaaggt aaagcggcag cagacatcgc cagccgggtg agcggcgtga
    14281 aacgcgtgac caccgccttt acgtatatta agtaaccggt gtgccgggtg gcgataaaaa
    14341 tgtgtaaatc gcgtcgccat ccggtaaatc atccggcttc gctaccccgc tttttcccgc
    14401 agttgcgatg aggtcagaat cgtcacgcct tcttgtgctg gctccagcgc ttccgccagc
    14461 atggcccgcg ccacatcccg cgcatcgatc gatttccagt ttcctggcag cagccggaat
    14521 agcggagcga aaagcgtttc attcacccgc cgcgttgttc tgtcgccgag cagcatagaa
    14581 ggccgggcaa tcgtcaaacg aggccaattt tgcgcgatta acgcctcctc catttctcct
    14641 ttcacccgat tgtagaaaaa cggagagtgc gcgtttgctc ccattgcgct gaccaccaac
    14701 atgtgctgcg cgcccagtcg acgcccggtc agcgcggtat caaccaccag cgtataatcc
    14761 gcatgaataa acgccgcttt acttcccgct tcacgccggg tcgtgcccag gcagcaaaaa
    14821 acaatatcca ccgggtcggt cacctgagct aacgcgtcgg taagctgcgg atcgtgaggg
    14881 ttataaacgc cgacaatatc cgtcagcggg cgacgcgttg gcgcggcgat cgcgctcacc
    14941 tgcggcgtgt tgattaacat tctcagcaga tgtccgccga ccagtccggt cgcgccggta
    15001 atcagtacct gactcatcct cgctccttta cagatttgtc caccttgcac tctcggccct
    15061 atcgaccagg cttaatagtc tacgaggtaa gtatccatca ttgtggaaaa tttgccttac
    15121 ccgacgccac cactgcggag gaaacgcatg agtaagaaaa ttgccgtttt gattaccgat
    15181 gaatttgaag attcagaatt tacctcgccg gctgcagaat tccgtcaggc cggccatgag
    15241 gtcatcacca tcgaaaaaga ggcgggtaaa acggtgaaag gaaaaaaagg cgaggccagc
    15301 gtcaccattg ataaggctat tgatgacgtt cgtcccgacg agttcgacgc cttgctattg
    15361 ccgggaggtc attcgccgga ctacctgcgc ggcgacagcc gtttcgtgga ttttacccgc
    15421 gatttcgtta acagcggtaa accggttttt gccatttgcc acggcccgca gttgttgatc
    15481 agcgccgatg tcattcgtgg ccgcaaactc acggcggtga aaccgattat tatcgatgtg
    15541 aagaatgcgg gcgcggaatt ttacgatcag gaagtcgtcg tcgataaaga tcagctggtg
    15601 accagccgca cgcctgacga cctgccggca tttaaccgcg aggcgctacg cctgctgggc
    15661 gcgtgagtca cgtaaccagt gcagtttttt accaaacccc agcgtgttgt cggtgaattt
    15721 aatttcatcc agccgaattt cccataccgg cgctggcagc accctggcga ccgggaagcg
    15781 acgaaggtaa gctttacgcg cggcgtcgct ctcctgcccc tccagacggc gaatttcccc
    15841 tttaaactgc acgccgcgaa tgcgcgccac cgttttcggc tgaccattga ccgttcccgc
    15901 aactggcgcg cacgcgccgg acatttgcgc atggcgggtt ttatcatccg ttaacagata
    15961 cagcgcgacg ttttgcgcat cgaacaaata aaacgcattg gcgcaccaca gctctccctc
    16021 atggtgtacg caccaggtca ccacgtgttg tttcgccagc caacggccaa tagcggtaag
    16081 tgtgtccatc tttattctcg cttatactgg gaacctgaaa attatcatgc tgatggcgac
    16141 aatgacaccc tggtatctgt atctgattcg tactgcagac aatgcgcttt acaccggaat
    16201 aaccaccgat gtggcgcgtc gttacaggca gcatcaaacg ggaaaaggcg caaaagcatt
    16261 acggggaaaa ggcgagttaa cgctggcgtt tgcggcgcag gtcggcgatc gctcgctggc
    16321 cctgcgcata gagtatcgca tcaaacagct cacaaagcgc cagaaggagc gccttgtgac
    16381 ggaacgcgaa gcgtttgagg cgctgctgtc cagcctgcaa acgccggtgc ttaaaaacga
    16441 ttgaagtggt cgtgatactc caccagcccc gtcacgccct ccagcgcatc ctcagccaaa
    16501 cggtgtacct ggaaagcgct ttccgtaccg ggccaacggc agtgaagatc gtaatgtgcg
    16561 gccagttcaa aaccgaagcg gctatataac gccgggtcgc ccagcgtcac gaccgccgcg
    16621 tagccgaact cgttgagcga atccagccct tcatacacta actggcgcgc cagcccttgc
    16681 ccgcgatact tttcatcgac cgccagcggc gccatgccga cccactgtaa atcttcgccc
    16741 tgcacatcaa ccgggctaaa ggcgacatag cccactacct ggccttcatc atccgtggcc
    16801 accagtccga gcgtcagaaa accatcttca cgcaaatcgt gaaccagctt cgcttccgca
    16861 tcgctttcga atgaacggcg taacagcgca tcaataccag gcgcatcaat gggaatttct
    16921 actcgaatta gcatggttca cctaccgagg tctgtttggt ttccggcgag tttttcattc
    16981 ccgcctcaac aaaatccgcc agttgcagca gcataatgcg taacgctttc ggcatctgct
    17041 ccagttcgat ggcgtccatc agattcttca catacaaccc taactcagta tcgccttcaa
    17101 tgaccagtcg acgctggaaa aagagcgtat ccggatcctg tttacgggcg gcgatcatta
    17161 gcagatcgct ggcgtcggcg ctaaaactga cgtcagcatc cgcctgctgg ctaacgatca
    17221 gcttttcatt ttcaaccgtg gtataccatt ttaagtcgat gtcacgaaca tgaatgctta
    17281 accaacgacc ttcgaggaat tccagctctc catcggccag cgcctgacga aactgccagc
    17341 tcagaacctg ttccagaacc tggcgcttta gcgcaaaggg cgtcagttta accggtacac
    17401 tcatcagaga cgggccagca tggactaagc gtgaacgcag tttatctaac acgagcttta
    17461 ctccctgttt caatagtcct gttattttgc catatccaat aaatcacatg gcggcgtaaa
    17521 tcaacaattg ggtctgattt tctaccccat tattggtgtt accaatacgc ctttaactgc
    17581 cttaaatcaa aaattgtcgc agcaaggtta actaaaatcc ctgttcgtta acaattttgc
    17641 gtcgcagacg taaccctcag gataaattat ggagctgctc tgccctgccg gaaatctccc
    17701 ggcgctgaag gcggccatcg aaaacggcgc tgacgccgtt tatatcgggt taaaagacga
    17761 taccaatgcc cgtcattttg ccggccttaa ctttaccgaa aaaaaattgc aggaagcggt
    17821 gagttttgtt caccagcatc gccgcaaatt acacatcgcc attaatactt ttgcgcatcc
    17881 ggacggctat gcccgctggc agcgcgccgt ggatatggcg gcgcagcttg gcgccgacgc
    17941 gctgattctt gccgacctcg ctatgctgga atatgccgca gagcgttacc cgcatattga
    18001 gcgccatgtt tccgttcagg cctcggcaac caacgaagaa gcgattcgct tttatcaccg
    18061 caactttgat gtccaccgtg tagtactgcc gcgtgtactg tcgattcacc aggtaaaaca
    18121 actggcccgc gtcacgccgg tgccgctgga ggtattcgcg tttggcagcc tgtgcattat
    18181 ggcagaaggt cgctgctatc tttcttctta cctgacgggg gagtcgccca ataccgtcgg
    18241 cgcctgctct cccgcccgct ttgtccgttg gcagcaaacg ccgcaggggc tggaatcgcg
    18301 cctgaatgat gtcctgattg accgttacca ggatggcgaa aacgcaggct acccaacgct
    18361 gtgtaaaggc cgctatttag tggacggcga gcgctatcac gcgctggagg agccaaccag
    18421 cctgaacacg ctggaactgc tgccggagct catggcggcg aacatcgctt cggtgaagat
    18481 cgaaggccgc cagcgcagcc cggcctacgt cagccaggtg gcgaaagtgt ggcgccaggc
    18541 gatagatcgc tgcaaagccg ccccgcaaaa cttcgttcca cagcgcgact ggatggagac
    18601 gctcggcgcg atgtccgaag gcactcaaac cacgcttggc gcatatcacc gtaaatggca
    18661 gtgagaggag ctatgaaata ttccttagga ccggtgcttt attactggcc gaaagagacg
    18721 ctggaagatt tttatcagca ggccgcaaaa agcagcgctg atatcattta tctgggcgaa
    18781 gcggtgtgca gcaaacgtcg cgcgactaaa gtcggcgact ggctggaaat ggcgaaatcc
    18841 ctcgctgcca gcggtaagca ggtggcgctc tccaccctgg cgctggtaca ggcgtcatct
    18901 gaattaagcg agctgaaacg ctatgtggac aacggcgatt ttctgctgga agccagcgat
    18961 cttggcgtgg tgaatctgtg cgccgagcgc aaactgccgt ttgtcgccgg ccatgcgctg
    19021 aattgctaca acgcggtcac gctgcgccgg ttgctgaaag aaggcatggt acgctggtgt
    19081 atgccggtgg agctctcccg cgactggctg gtgaatttgc ttaatcagtg cgatgaactg
    19141 ggcatccgca atcagtttga agtggaagtg ttgagctacg ggcatctgcc gctggcctac
    19201 tccgctcgct gctttaccgc ccgttcggaa gaccgcccga aagatgaatg cgaaacctgc
    19261 tgtatcaagt atccaaacgg tcgtgacgtg ctctcgcaag agaatcagca ggtgtttgtg
    19321 cttaacggta ttcagaccat gagcggctat gtctataacc ttggcaacga actgacgtcg
    19381 atgcagggat tggtcgatat cgtgcggctg tcgccgttgg ggacggagac atttgccatg
    19441 cttgatgcct ttcgcgctaa cgaaaacggc ggcgcgccgt taccgcttgc cgcccatagc
    19501 gactgtaacg gctactggaa gcggctggcc gggctggagc tacaggccta gccggatggc
    19561 agcatcaata ccttatccgg cctacaaata gcgctcccga aggcccgata agcgcagcgc
    19621 catcgggcat tgtttttgcc attagtctca taaagctcac tttgttaaca acattcgcta
    19681 atctttaatg cagtattaaa agattaatcg gtaacaaagt gagccgttat gactgacaaa
    19741 actattccgt tctcggtgct ggatctggcg ccgatccctg aaggatcttc ggcaaaagaa
    19801 gccttcacgc actcgcttga tctcgcacgg ctggctgaaa agcgtggcta tcaccgctac
    19861 tggctggcgg aacatcacaa catgaccggt atcgccagcg cggcgacctc ggtattgatt
    19921 ggttatctgg cggccaatac cacaacatta catcttggct ccggcggcgt gatgctgcct
    19981 aaccattcac cgctggtgat tgccgagcag ttcggcacgc tgaatacgct ctacccggga
    20041 cgtatcgact taggattggg acgcgcgccg ggtagcgatc agccgacgat gcgcgcgctg
    20101 cgtcgccata tgagcggcga tatcgataac tttccacgcg atgtcgcaga gctggtggac
    20161 tggttcgacg ctcgcgatcc taatccgcat gtgcgcccgg tgcccggcta cggcgagaag
    20221 atcccgatct ggctgttggg ctccagcctg tatagcgcgc aactggcggc ccagcttggc
    20281 ctgccgttcg cctttgcttc gcatttcacg ccggatatgt tgttccaggc gctgcatctg
    20341 taccgtactc agttcaaacc ttcagcgcgg ctggaaaaac cgtacgcgat ggtgtgtatc
    20401 aatattatcg ccgccgacag caaccgcgac gccgaattcc tgtttacctc catgcagcag
    20461 gcttttgtga agctacgccg tggagaaacc ggccaactgc cgccgccgat tgagaatatg
    20521 gaaaccttct ggtcgccatc cgagcagtat ggcgtgcagc aggcgctgag tatgtcgctg
    20581 gtcggcgata aagcgaaagt ccgccacggg ctggtgtcca ttctgcggga aacccaggcg
    20641 gatgaaatta tggtaaacgg gcagattttc gaccaccagg cacgcctgca ttcgtttgat
    20701 ttagcgatgg atgtgaagca ggaattgttg gggtagcgca ttgttttgcc cggtggcgct
    20761 tcgcttaccg ggcctacagc atcaagtagg ccggataagg tgcaaccgcc atccggcaca
    20821 ataacgttac tggtacaccg gcagcaaatt aaagctcgac agaatatgga taaccgcgtt
    20881 gccgacaccg aagaccagaa tcagggcaat catcggttta ccgccccaga cgcgaaattt
    20941 tgggctgccg aaacgttcgc gagatttgcg cgccaacagc gcaggcacaa tggccgccca
    21001 gatagttgca gctaaacctg catagccaat ggcgtacaga aaaccgttcg ggtacagcag
    21061 gccaccaatc atcggcggca ggaaagtcag cagcgccgtt ttaaaacgtc ccattgccga
    21121 gtcatcaaaa ccaaacagat ccgccagata gtcaaacagc cccagcgtca cgccaaggaa
    21181 ggaactggcg accgcaaagt tagagaacac caccagcagc agatccaggc tgcggctgtt
    21241 cagcacgccg ctcaacgcct gtaccagcac atcaatattg ccgcctttct gcgcaatgcc
    21301 gataaattcc ggacgtggga tgttgcccat cgtccccagc agccagacgg aatagagcgc
    21361 cagcgccagt aacgtcccat aaatcaggca tttcacgatg gtgcgcggat ctttgccgta
    21421 atatttcatc aggctcggta cgttaccgtg ataaccaaaa gaggccagac aaaatggcag
    21481 cgtcatcagc aggtacggcg tatatgacgc gtggctttca gccacgttaa acaacgtggt
    21541 cggctgaacg tgccctaaca ggctgccgaa ggtcaggaag aaagtaatca ctttcgcgcc
    21601 cagcacaatc gccgtcatcc ggctgaccgc cttcgtactc agccacacga caaacgccac
    21661 cagcagcgca aaggcaaaac ctgccgctcg cgccggaacg ttcagcgaca tctcagcaaa
    21721 ggtatgatgc agaattgagc cgctcgccga gatataggcg taagtcagga tgtagagcac
    21781 aaaggcaata gagatgccat ttaccacgtt ccagcctttc cccaacagat ctttggtgat
    21841 ggtgtcgaaa ctcgaaccaa tgcggtagtt aaggttagct tcgaggatca tcagcccgga
    21901 gtgcagcata caaaaccagg taaagaccag cgccgccatc gaccagaaga accacgcccc
    21961 ggacatgacc accggcaggg agaacatccc cgcgccaatg atggtgccgc cgataatcac
    22021 cacgccgcca agcagcgaag gtgacgtttg ggtggtggta agtgttgcca ttcagctctc
    22081 tctccagtca tttatagtgt gactatctct caatacgttg cactgtacca gtacacgagt
    22141 acaaaagaaa taaaaaaagc cccgattgtg acgatcgggg ctgtatattt tactttacgc
    22201 tgtgaatgcg caggtcagcg tgagttacgc atcaccgccg aaacgacggc gaccggtaga
    22261 gtcatcacga cgcggaccac ggctttcacg acgttcgccg ctgaagcgac gaccatcacc
    22321 acgaccacct tcacgacgtt cgccgctgaa attacgaccg ccttcacgac gttcgccact
    22381 gaagctacga ccaccgccgc gacgttcgcc gcccgcgtgc ggaaccgcat cacccaacag
    22441 ctgcatattc atcggcttgt tcagaatgcg agtacgcgtg aagtgctgga gcacttcgcc
    22501 cggcatacct ttcggcagct cgatggtgga gtgagacgcg aacagcttaa tgttaccaat
    22561 gtaacggctg ctaatgtcgc cttcgttagc gatagcgccc acgatatgac gaacttcaac
    22621 gccgtcatca cggcccactt caatgcggta taactgcata tcgccaacgt cacgacgttc
    22681 acgacgcgga cgttcttcac gatcgccacg cgggccacgg tcattacgat cgcgcggacc
    22741 acggtcgtca cggtcacgga attcacgctt aggacgcatc ggcgcatccg gcggcagaat
    22801 cagcggacgc tcgccctgcg ccattttcag cagtgcggcg gccagcgttt cgagatccag
    22861 ctcttcacct tcggcagacg gctggatttt cgccagcagc gcacggtact gatccagatc
    22921 gctgctttcc agttgctgct gaactttcgc ggcgaatttt tccagacggc gtttacccag
    22981 cagttctgcg ttcggcagtt ccacttctgg aatggtcagc ttcatggtgc gttcgatgtt
    23041 gcgcagcaga cgacgctcgc ggttctcaac gaacagcagc gcgcgaccgg cgcgacccgc
    23101 acgaccggta cgaccgatac ggtgaacgta ggactcggag tccatcggaa tatcgtagtt
    23161 caccaccagg ctgatacgtt caacgtccag accacgtgcc gcaacatcgg tggcgatcag
    23221 gatgtccaga cgaccatctt tcaggcgttc cagagtctgc tcacgcagcg cctggttcat
    23281 atcgccattc aacgcggcgc tgttgtagcc gttacgttcc agcgcttctg ctacttccag
    23341 ggtcgcgttt ttggtacgta cgaagataat cgccgcatca aagtcttccg cttccaggaa
    23401 acgcaccagt gcttcgtttt tacgcatacc ccagacagtc cagtagctct ggctgatgtc
    23461 aggacgggta gtcacgctgg actgaatgcg cacttcctgc ggctctttca taaagcggcg
    23521 ggtaatgcga cgaatcgctt ccggcatggt ggcggagaac agagcggttt gatgaccttc
    23581 cgggatctgc gccataatag tttcaacgtc ttcgatgaag cccatacgca gcatttcgtc
    23641 ggcttcatcc agcaccagac cactcagttt agagaggtcg agggtgccgc gttttaagtg
    23701 atcaagcaga cgtcccggcg taccgacaac gatctgcggc ccctgacgca gggcgcgtaa
    23761 ctgcacgtca taacgctgac cgccgtacag ggcaaccacg tttacgccgc gcatgtgttt
    23821 agagaaatcc gtcatggctt cggcaacctg taccgccagt tcgcgggttg gcgccagcac
    23881 cagaatctga ggtgccttca gctcaggatc aagattgttg agcagcggta aagagaacgc
    23941 tgcggttttg ccgctaccgg tctgggccat gcccagcacg tcgcgaccgc ccagcagatg
    24001 cggaatgcac tctgcctgga ttggagatgg tttttcgtaa cccagatcgg taagggcttc
    24061 aaggatagga gccttcagcc ccagatctgc aaaagtggtt tcgaattcag ccatgtagta
    24121 cgtgtgcctc aaaattaatg gcggccagtc tacataactc atcatgaaat tgatctgcaa
    24181 ttttcattga aaagtgtgaa ccggctcaaa gtaggtgtat taacgaacaa caacgccctc
    24241 acccgcgaag gtgatggcaa tcaaaaagat tacgggctga tatgttcgtc agctattgct
    24301 ggtccgattc tgccaggtca tcttggtcct ggcccaggag cgataattcc aacaatgcgt
    24361 atcggtgctc aacaaagtta tgaacgttgt tggccaccgc cagtttgaac agagccgtgg
    24421 cgctgtccaa atcccccaga cttaggtaat acttacctaa atagaagttg gtttcactga
    24481 gatgctcagc gagcgaggtg ttatccgttg cgtccgcctt gagcctttcc atcagcgttg
    24541 cttcgctaat gtcgcccagg tagaactcga caatgttcca tccccattgc tctttatccg
    24601 atttttcgaa gcgtgctttt aacgcttctt tcgcctgctt ctcattaagc ttctgctcaa
    24661 caagatacag ccacaggctg cggtaaggat cattgggatc gtcttgataa aacgccagca
    24721 gatcatcttg cgctaactta tcacggccgc cgtaatacaa tgcgataccg cggtttaagt
    24781 gcgcgtagtt gtaagttgga tcaagctcta gtacagaatc aaacgcttca taggcagcat
    24841 caaaattgcc tgcctgcgtt aaataaatgc ctaagtaatt gaatacttca ggcatatccg
    24901 gtctgattgc cagcgcttgt gaaaaatcat ttcgcgctaa tgccctcaaa ccaagactat
    24961 catacaacac tccgcgctca tataaaagct gtgcgcgttc gtcatcggtt aaagcccgac
    25021 tggcaagaat ctgttccata cgcgccagaa tcacttcctg ctgtaaagtc ggttgcaatg
    25081 gtactgcgag gacttcactt ttacgccagg cggaattact gcatcctgca agcgtaagtg
    25141 ctgtcgcaac gaaacaccag cgcaaaaaag gcttcatttc ccactcccga agacaacgat
    25201 tgaatgaacg tcctgttccc cggtggctca acaaggcgtc cagccaggtc taaagccccc
    25261 cgcactgcgg agggcaaaag gctaccttac tcggcctgtt cgctcgccgg agcttccggc
    25321 gcagccgcag gttgagactg ctcggttgct tctttaatgc tcagacgtac acggccctgg
    25381 cggtcaactt ccagaacctt aaccgggact tcctgaccca tctgcagata atcggtcact
    25441 ttctctacac gcttatccgc gatttgagag atgtgaacca gaccttcttt accgccgccg
    25501 atggcaacaa acgcgccaaa gtcaacgata cgggtcactt tactattgta gatacggccg
    25561 acttcgatct ctgcggtgat ctcttcgata cgacggatag cgtatttcgc tttttcaccg
    25621 tcggtcgccg cgatcttcac agtaccgtca tcttcaattt cgatggtggt gccggtctct
    25681 tcagtcagcg cgcggatcac agaaccgcct ttaccgatca cgtctttgat cttgtccgtg
    25741 ctgatcttga tggtatggat acgcggcgca aattcagaga tatcgccgcg cggcgcgttg
    25801 atcgcctgtt ccatcacgcc caggatgtgc agacgcgcac ctttagcctg gttcaacgca
    25861 acctgcatga tctctttggt gataccttca attttgatat ccatctgcag cgcagagata
    25921 ccgtcgcggg aacccgccac tttgaagtcc atatcgccca ggtgatcttc gtcgcccaga
    25981 atgtcagaca gtacaacgta gttgtcgcct tctttcacca gacccatagc gatacctgct
    26041 acggcggctt taattggcac gccagcgtcc atcagcgcca gagaagcgcc gcacacggaa
    26101 gccatagaag aagaaccgtt ggattcggtg atttcagaca ccacgcgaac ggtgtacggg
    26161 aatttatcca tgtccggcat cactgccagc acgccgcgct tcgccagacg accgtgacca
    26221 atttcacgac gcttcggaga accgaccatg ccggtttcgc ctacggagta cggagggaag
    26281 ttgtagtgga acaggaagct gtcagtgcgc tcgcccatca gttcatcaag cacctgcgcg
    26341 tcacgggcag tacccagagt cgcggtaacc agcgcctgcg tttcaccacg ggtaaacaga
    26401 gcggaaccgt gagttcgcgg cagtacgcca gtgcgcacgt ccagaccacg gatcatgtct
    26461 ttttcacggc catcaatacg cggctcgcct gccagtacgc ggctacgtac cacgtttttc
    26521 tcgatggcgt gcaggatttc acccagctcg ttagcatcca gagtttcatc ttctgcaata
    26581 agctgctcga tggtttcgga tttgattacg tcaacctgag catagcgctc ttgtttatcg
    26641 gtgatgcggt acgcgtcgct cagacgagat tcagccagcg cagcaacacg cgcgttcaac
    26701 gcgtcgttga cggcttccgg ctgccagtcc caacgcggtt taccggcttc tttcaccaga
    26761 tcgttgatcg cctggataac aacctgctgc tgctcgtgac cgaataccac cgcgcccagc
    26821 atagtgtctt cgctcagcag ttcagcttcg gattccacca tcagcacagc cgcttcggta
    26881 ccggcaacca ccaggtccag cttgctttct ttcagctcgt cctgggtcgg gttcagtacg
    26941 tactggtcat tgatgtaacc tacgcgcgcc gcgccgattg ggccgttgaa cggaatgccg
    27001 gacagcgaca gcgcagcgga tgcgccgatc atcgccacga tatccgggtt aacctgcggg
    27061 ttaacggaaa cgacggtcgc aataacctgc acttcgttaa cgaaaccttc cgggaacagc
    27121 ggacgaaccg ggcggtcaat cagacgcgcg atcagggttt cgccttcgct tggacggcct
    27181 tcacgacgga agaagctgcc cgggatacga ccagcagcgt aggtacgctc ctgatagtta
    27241 acggtcagtg ggaagaagtc ctggcctggc ttggcttttt tctggccgac aacggtaacg
    27301 aatacggcgg tgtcatccat gcttaccata acagcggcag tggcctgacg cgccatcatg
    27361 ccagtttcca gcgtaacggt atgctggccg tactggaatt cacgaacgat cggattaagc
    27421 aaaataatat cctttccaat ttttgacggc acaatacgcg ccgtcgttaa tacccgatct
    27481 tctgcgcatc ctcgcgacta atgacaaccc taaccctgat atgggtaaag cctctcatta
    27541 gccgcgcgaa cctctgcaac ggaagatcat tcatagcaac aatacattag tttccagcga
    27601 attgctgcca tctgctggaa aaaaggggcc atgaaggccc cctctttctg aaactcgaaa
    27661 gaattagcga cgcagaccca gacgctcaat cagcgcggtg tagcgtgcaa catctttacg
    27721 tttcaggtag tcgagcagtt tacgacgctg agaaaccata cgcagcagac cacgacggct
    27781 gtggtgatct tttttatgct ctgcaaagtg accctgcagg tggttaatct gtgcagtcaa
    27841 cagagcaacc tgaacatcgg tagaaccggt gtcgtttgcg tcacgaccga actcagaaac
    27901 gattttagct gtagcttcag tacttagaga cattttaaaa ctccaaagta tttaagaatg
    27961 agaggacgcc gatctctaat tcagcgatcc cagtgtacgc cgcgtaaact gttaaataat
    28021 ttacgcgacg ttaagcggcg gtattctact cgcagcgctc tcttatcgca agacgaagcg
    28081 acattacgcc gggtactcta ctaccagccg acgaggcgcg acacggcctt cgtcgtcaat
    28141 ttcgcccata ccgataaatt tatcgtcttc accttccgtc acacgaacca gtcccttcaa
    28201 cggcgcgccc gtggtacgaa ccgggttgcc atttttgaag tataccgaag atgttaacgg
    28261 cagattaaca acaggatagt ccgaagccgg actatccatt ggcatcaata atggatcgag
    28321 caactgcgcc gccggaacgc cctgctgttc cgcctgtgct accagcgtct gcaagtgctc
    28381 cagcgtcacc atacgatcca ccggatactt gctgaccgtc agacgacgca ggtacgttac
    28441 gtgcgcgcca cagcccagtt tctcacctaa atcatcaata atagtgcgaa tataggtgcc
    28501 tttggagcaa tgaacttcca gctccagctc gttaccttca tggcgaataa acagcagctc
    28561 atagacggta atcgggcggg cttcgcgcgg cacttcgata ccctggcggg catattcgta
    28621 cagcttcctg ccctgatact tcagcgccga atacatcgag ggaatctgtt cgatatcccc
    28681 acgaaaggtc tccagcgcgc tcgcaagctg ctcagcgctg aaagtcaccg gacgctcctg
    28741 cacgatttga ccatcggcgt cagaggtatc tgtgcgctgc cccagacggg caataacacg
    28801 atagcgtttg tcagaatcca gcaagtactg cgaaaatttt gtcgcttcgc cgaggcaaat
    28861 cggcaacatg ccggtcgcca gcgggtccag cgcgccggta tgcccggcgc ggttggcatt
    28921 gtagatgcgc ttaactttct gcagcacgtc attgctggac ataccctgcg gcttatccag
    28981 caacagaacg ccgtgaatgt cgcggccacg acgacgagga cgactcatca gtcctccttg
    29041 ctgtcgtccg ggttcacacg acgttcttcg tcatgtttca ccacgttagt caccaggttg
    29101 gacatacgca tcccttccac cagcgagtta tcgtagaaga aggttagttc cggcacgatg
    29161 cgcagacgca tcgctttacc cagcaagctg cggatgaaac cagacgcttc ctgcagggcc
    29221 ttaatgccgt ttttcacagc cgcttcgtcc tgatcgttga ggaacgtcac gaatactttg
    29281 gcgtatgcca gatcgcggga catttcaaca cccgatacgg tggtcatcat acctacacgt
    29341 ggatctttga tttcgcgttg caggatgagc gcgatctctt tctgcatctc ttgcgctacg
    29401 cgctgcgggc gaccaaattc tttcgccata ataaattctc cagaataaag acaaaaaagg
    29461 ggccataagc ccctttttaa atttcttgcc gggtggcgct tcgcttaccc ggcctacgcc
    29521 taatcatctt ctaaggattt tggattgcaa caaggcggca agctcgtaaa tccccgggag
    29581 catagataac tatgtgaccg gggtgagcga gcgcagccaa cgccgttgcg gcccaaaaga
    29641 cgacgaagat taagcgatgg tacgttggat ctcgataatc tcgaacactt caatcatatc
    29701 gccaacgcga acgtcgttgt agttcttcac gccgatacca cattccatgc cgttacggac
    29761 ttcgttaacg tcatctttga agcggcgcag ggattccagc tcgccttcat agataaccac
    29821 gttgtcgcgc agtacgcgga ttggattatg gcgtttaatt gtaccttcgg taaccataca
    29881 gcccgcgatc gcgccgaatt tcggcgattt gaacacatcg cgcacttcag ccagaccgat
    29941 gatctgctgt ttcagttccg gagacagcat gccgctcatc gccgctttca cttcgtcgat
    30001 caagttatag atgacggagt agtaacgcag atccagactt tcggattcaa tcactttacg
    30061 cgcagaagca tcagcacgaa cgttgaagcc caccagaatc gcgttggacg ccgcagccag
    30121 ggtcgcgtcg gtttcggtga taccacctac gccagaaccg atgatcttca ctttcacttc
    30181 gtcggtagac agtttcagca aggagtcgga gatcgcttcc acggaaccct gtacgtcagc
    30241 cttcagcacg atgttcactt cgtgaacttc gccttcggtc atgttgacga acatgttctc
    30301 gagtttagat ttctgctgac gagccagttt aacttcacgg aatttaccct gacgatacag
    30361 agcaacttca cgcgctttct tctcgtcgcg aaccacggtc acttcgtcac cggcagccgg
    30421 aacgccggac aggccgagga tttccaccgg aatggacgga cccgcttcca gcacttcctg
    30481 acccagttcg ttacgcatcg cacgcacgcg gccgtattcg aagccacaca gcacgatatc
    30541 gcccttatgc agcgtacctt cgcgtaccag aacggtagcc accggaccac gacctttatc
    30601 caggaaggat tcgatcaccg cgccgctcgc cataccttta cgaaccgctt tcagttccag
    30661 aacttcggcc tgcagcagga tagcgtcaag cagttcgtcg ataccggtgc ccgctttcgc
    30721 agacacgtga acgaactggc tctcgccgcc ccactcttcc ggcagaatgc cgtactggga
    30781 cagttcgttc ttcacacgat ccggatctgc ttccggctta tcgattttgt tcaccgcaac
    30841 cacgaccggc acacctgccg ctttcgcgtg ctggatagct tcgatagtct gcggcatcac
    30901 gccgtcgtct gctgcaacaa ccagaaccac gatatccgtt gcctgagcac cacgagcacg
    30961 catggaggta aacgcggcgt ggcccggggt gtccaggaag gtgatcatcc cgttgtcagt
    31021 ttcaacgtgg taagcaccga tgtgctgggt aatgccaccc gcttcgccag aggccacttt
    31081 cgtggaacga atgtagtcca gcagagaggt tttaccgtgg tcaacgtggc ccatgatggt
    31141 cacaaccggt gcgcgcggtt cagccgcagc gccggtatca cggtcgctca ttaccgcttc
    31201 ttccagttcg ttttcacgac gcaggataac tttgtggccc atctcttcgg caaccagctg
    31261 tgcggtttcc tggtcgatga cctggttgat ggtggccatg gcgcccagct tcatcatcgc
    31321 tttgatgacc tgagaacctt tcaccgccat cttgttcgcc agttcgccga cggtgatggt
    31381 ttcaccgatc accacgtcac ggttaacggc ctgagcgggc ttctggaagc cttgctgtaa
    31441 agaagaccct ttacgcttgc cgcctttacc gccgcgaacc gcagcacgcg cttcttcgcg
    31501 atcggctttg gattcggcat gtttgccttt tttcgccgga cgcgccgctt ttgcattacg
    31561 gccacgacca cgaccacctt ctacttcacg atcgttttcg tcttcggcct ggcgcgcgtg
    31621 ctgagaagtg gtgacatgat agtcactggt gtcttctact ggctcaggcg ttgcggtcca
    31681 tttgttttct tccgccatgc ggcgagcttc ttctgctaca cgacgcgctt cttcttcgag
    31741 tttgcgacgt gcttcttctt ccgctttacg cttcagctct gcagcttcat tctcacggcg
    31801 ggctttttcg gcctgggcgg ttttggtcat atcgtcagtc tgttgattgc tcactttgtc
    31861 tttttccgca gcttcacgtt tcgctttttc agcggcttca cgcttagctt gttctgcggc
    31921 ctcgcgttca gctttttgtt gcgcctcgcg tttggcctgt tcttctgcct cacgacgggc
    31981 ttgctcttcc gcttcacgct gcgcctgctc ttccgcggcc aggcgttcag cctcttgcgg
    32041 atcgcgtttc acaaaggtgc gcttcttgcg gacttcgatt tgtaccgatt tactttttcc
    32101 accggtacca ggaatattca gggtgctgcg cgttttacgc tgcagcgtca atttatcggg
    32161 gccagaaacc gcttcgcggt tcaggtgcgc cagtaaagtc tgtttttctt gtgcggacac
    32221 agagtcgtca gcagatttcc ggatacctgc atcagcaaac tgctgtacca ggcgatccac
    32281 ggaaacctgt ctctctgcgg ccagcgcttt tagggttaaa tctgtcatgc tgttccttcc
    32341 tgctacagtt tattacgctt cgtcgccgaa ccagcaaata ttacgggcag ccataatcag
    32401 ctcaccggct ttttcgtcgg tcaacccttc gatatcagcc agatcatcaa tgccctggtc
    32461 ggcgagatct tccagcgtac aaacaccacg agccgccagt ttgaaagcca tatcgcgatc
    32521 taatccttcc agattcagca gatcgtcagc cggtttgtta tcacctaggc ttgcttcctg
    32581 gtcctgcgcc agagtggcca gtgcgttttt agcacgctcg cgcagtgctt caacggtcgg
    32641 ctcatcaagg ccgtcaattt ccagcagttc tttcattggc acataggcca gttcttcgag
    32701 cgtggagaaa ccttcttcta ccagaacggt cgcgaactct tcatcaatat caagatattt
    32761 agtaaagatc tcgatagcgg catgtgcttc agcctgatgt ttagcctgca agtcatcaac
    32821 ggtcattacg ttgagttccc agccgctcaa ttgcgaagcc aagtggacgt tctgaccatt
    32881 acgtccgatc gcctgcgcca gattaccggc ttcaacggcg atatccatgg tatgtttatc
    32941 ttcgtccacc acgatagacg cgacatctgc cggcgccatc gcattaatga cgaactgcgc
    33001 cgggttatca tcccacagca cgatatcgat acgctcaccg cccagttcgg tagagaccgc
    33061 ctgaacgcgc gcgccgcgca tccccacgca agcgccgacc ggatcgatac gcttatcgtt
    33121 ggttttcact gcgattttcg cacgagaacc cggatcgcga gccgccgctt taatttcaat
    33181 cacttcttcg ccgatttccg gcacttcgat gcggaacagc tcgatcagca tttccggctt
    33241 ggaacgggtg acgaacagct gcgcgccacg cgcttccggg cgaacagcat acagcacgcc
    33301 gcgaatacgg tcgccagggc ggaagttttc gcgcggcagc atatcttcac gcagaatcac
    33361 cgcttcagcg ttaccggcca tcccttcgga tttaatttcc aaagagatat tgtcgcggtt
    33421 cactttcttc accacgccag tgacgatttc gccttcctgg tcgcggaact gatcgacaac
    33481 catcgcgcgt tcagcttcac ggactttctg cacgataacc tgtttcgcag tctgcgtggt
    33541 gatacggtca aaggtgacag attcaatctg atcttcaaca tagtcgccga cattcaggct
    33601 ttcgtcttca aagcgcgccg cttccagcgt aatttccttc gtcggcatgg tcacttcttc
    33661 aacgatcaac caacggcgga aagtatcaaa atcaccgctt ttacgatcga tttctacacg
    33721 aacatcgatc tcctgctcat attttttctt tgttgctgtc gccagcgcac tttccagcgc
    33781 ttcaaaaatt ttttcgcgtg gcagcgcttt ttcgttggag acggcttcaa caacagccaa
    33841 aatttctttg ttcatcgcgg gcttttcacc tcatccagac tgttaaaagt ggggaaccag
    33901 gttcgccttc tggatattac tcagcgcgaa cacttcatct ttgccttcga ctgtgacggt
    33961 aatcatttca ccgtccaccg ctttgataat gccctgccac ttgcgacggt tctgtaccgc
    34021 catgcgaaga accagcgcga cctcttcacc ctggaaacgc gcataatgat cggcagtgaa
    34081 cataggacgg tcgagacccg gtgacgagac ttcaaggttg taagccacgg agataggatc
    34141 ttcaacgtcc agcaccgcgc ttacctggtg gctcacatca gcacaatcat caacattgat
    34201 gccatcttca ctatcaatat agatgcgcag tgtggatgtg cgaccgcgaa taaattcgat
    34261 gccgaccagc tcgtagccta aggcttcaac tggcgctgta atcatctctg ttaatttttg
    34321 ctctaatgtg gacaagccca cccccaagac ataaaaaaag ggcctaaagc ccagttattc
    34381 tgtagtcaga taacaaaaaa ccccgataaa tcggggcttt agataactga accctataac
    34441 cgcaacggcg gtctggtgta ccttccgaaa gaattttttt caaatccagc tacgaaggac
    34501 ataatcttca cagtatattt gaaaaagaac tctaagggaa agtggttgcg ggggccggat
    34561 ttgaaccgac gaccttcggg ttatgagccc gacgagctac caggctgctc caccccgcgc
    34621 ctgaaacgtg gcaaattcta ctcgttttgg gcaaaatttg caaatactgc tgggatttgg
    34681 taccgaggac gggacgtaaa atctgcgcac agtatagtga ccaggcatga gttatgtcaa
    34741 ccctattccc aatatgcaga tgaatgaata tcactcttcg ttatactcat cccacctctc
    34801 ctgcttatac acgcatttca caacgttatt tcagtaaacc ttcactaaat gcttcctgtc
    34861 tctgctaaaa gatgattaaa tgaaaactca tttattttgc ataaaaatgc actaaagcag
    34921 aaaccgatct cattatcagt caatcaagca gggttctatt ctatgacgac gattcttaag
    34981 catcttccag caggtcaacg tattggtatc gctttttccg gcggtctgga cactagcgcc
    35041 gcgctgctgt ggatgcgaca aaaaggagct gtcccatatg cctatactgc gaatctggga
    35101 caaccggatg aggatgacta tgacaccatt cctcgtcgcg caatggagta tggcgcagag
    35161 aatgcccgcc tgattgattg ccgcaagcag ttggttgcag aagggatcgc agcgattcag
    35221 tgcggcgctt tccataatac gactggcgga ctgacctatt tcaataccac gccgctgggc
    35281 cgtgccgtga ccggcacgat gctggtcgcc gcaatgaaag aagacggcgt gaatatctgg
    35341 ggcgacggca gcacctataa aggcaacgat attgaacgtt tctatcgtta cggcctgctg
    35401 accaacgccg agctgcagat ttacaaaccg tggctggata ccgactttat cgatgagctg
    35461 ggcggccgtc atgagatgtc tgaatttatg attgcctgcg gtttcgacta taagatgtca
    35521 gtcgaaaaag cctactccac cgactccaac atgctcggcg cgacgcacga agcgaaagat
    35581 ctggagtttc ttaactccag cgtcaagatc gtcaacccga ttatgggcgt gaagttctgg
    35641 gacgaaagcg tgaagatccc ggcagaagag gtgaccgtcc gtttcgaaca gggacatcca
    35701 gtggcgctga acggtaaaac cttcagcgat gatgttgaga tgatgctgga agcgaaccgc
    35761 atcggcggac gtcacggcct gggcatgagc gaccagatcg aaaaccgtat cattgaagcg
    35821 aaaagccgcg gtatttatga agcccccgga atggcactgc tgcacatcgc ttacgagcgt
    35881 ctgttgaccg gtattcacaa cgaagacacc attgaacagt atcattctca tggtcgtcag
    35941 ttgggtaaac tgctgtatca gggtcgctgg ttcgactctc aggcgctgat gctgcgtgac
    36001 ggcctgcaac gttgggtcgc cagccagatt accggtgaag tgacgttgga gctgcgtcgc
    36061 ggcaacgact actccatcct gaacaccgtg tcagacaacc tgacctataa ggctgagcgt
    36121 ctgaccatgg agaaaggcga gtccgtgttc tcgccagacg atcgtatcgg tcagttgacc
    36181 atgcgtaatc tggacattac tgatacccgc gagaaactgt tcggctacgc gaaagcgggt
    36241 ctgttaaccg cctcttccgc gaccggtctg ccgcaggttg agaatctgga aaacaaagcg
    36301 aagtaaacat ttatcattct aaggccgcga aagcggcctt ttttatgcgc ggaatataag
    36361 gtgtctatag gcctgataaa cgtagcgtca tcaggcgttg taataatgtc ggatggcggc
    36421 gtaaacgcct tatccgacct acagaaaatc acaaataaca gacgaaaaaa aagacgcttt
    36481 tcagcgtctt tctttcggaa tattggtacc gaggacggga cttgaacccg taagccctat
    36541 taggcactac cacctcaagg tagcgtgtct accaattcca ccacctcggc acggatactg
    36601 ctattagcgc gggatatcgc tggtcggctg ggccggtgca gcaggttgag tctgctcggt
    36661 tttcgccggc gcgctcagat tttcccactc gcttccttta ttggttttgt tgctattgat
    36721 attacccaac accagactga tgatgaagaa cagcgtcgcc aataccgccg tcattcgagt
    36781 catgaagtta ccagaaccac ttgaaccaaa tagcgtagcg gaagcgcctg ctccgaagga
    36841 ggctcccata tcagcgcctt taccttgctg cagcatgatc agacctacaa ggccaattgc
    36901 cacaataagg aaaacaacta aaagagcttc gtacataatc aacctgttcc ttgcggagtt
    36961 gccgcgtacc aatgcttcta ccaataaagc gggattttta ctgtttccca ctgaagcggg
    37021 tgtgaatact aaccaaagcg aatgaccttc gcaagggcaa tttaagcgca ttgtatcaac
    37081 tgcggaaaaa aacagcaaaa gcgttgtttt ttgcgggcag taaggcggca accgccgcct
    37141 ttttagtcac ttaaacgctt aaacggcttt taccgcatcc gcgatacgat gggcgaaagc
    37201 cgtaacctgc gcttcatcct cgccttcaac catcacgcga atcagcggtt cggtaccgga
    37261 tttacgtagc agtacccgcc cacgattgcc gagcgtggct tctacgtccg ccgttaccgc
    37321 tttcaccgct tcattttcca gcggatcgcc gctaccagcg gtgtaacgca cgttaaccag
    37381 aatctgcggg aacattttca ttccgctgca cagatcgtgc agactcatat gattacgcac
    37441 catcgccgcc agaacttgta gccccgccac aataccgtcg ccagtggtcg ttttatccag
    37501 cagaataacg tgaccagagt tttccgcgcc gatgcgccag cctttttcct gcaatttttc
    37561 cagcacatag cggtcgccca ctttcgcccg ggcaaacgga atgccaagct gcttgagcgc
    37621 cagctccagc cccatattgc tcatcagcgt ccccaccgcg ccgccgcgca gttgcccctg
    37681 gcgcagccct tcgcgcgcga tgatatacat gatctgatcg ccatcgactt tattgccttc
    37741 atggtcaacc atgatgaccc ggtcgccgtc gccgtcaagc gcgatgccga ggtccgcctt
    37801 ctccgccaac acgcgcgcct gcaacgcgcg cacgtcggtc gcgcccactt cttcattaat
    37861 gttgacgccg tttggctcac agccgatggc gatcacggtc gcgcccagct cgcgcagcac
    37921 attcggagcg atgtggtagg tagcgccgtt ggcgcaatcc acaaccactt tcaggccgtt
    37981 gaggctcagt tcgttcggga aggtgccttt acagaactca atatagcgtc cggcggcgtc
    38041 gacgatgcgg ctggctttcc ccagctcggc ggagtctacg caggtgatct ctttttccat
    38101 ttcggcttcg atggcttctt ccacatcgtc aggcagtttc gtaccgtcga tagagaagaa
    38161 tttaatgccg ttatcataga acgggttatg ggaagccgag ataacgatac ccgcctccgc
    38221 gcggaaagtc cgcgtcagat aggcgacggc tggcgttggc ataggtccgg taaacgaggc
    38281 cgacagcccc gcagcggcaa ggcctgcctc cagcgcggat tccagcatat agccggaaat
    38341 acgcgtatct ttaccgataa tgattttacg cgaaccatga cgcgccagca cttttccggc
    38401 agcccaaccc agtttaagca cgaaatcagg tgtaatgggg gcattgccta cacgtccgcg
    38461 aatcccatcg gtaccgaaat atttacgatt actcatagcg tttgtttccc tttgcagaca
    38521 gagtggcttc caccacccgc atcgcctcta cggtttcttt gacgtcatgg acgcgaatga
    38581 tctgcgcgcc ctgcatcgca gcaattaccg cgcacgcaag gctaccgttc agacggtctg
    38641 atggtcccac gttaagtaac tgaccaacca tcgttttacg tgacatgccc accagcagcg
    38701 gcaggttaaa atgatgaaac tcacccagtc gcgccagtaa ggtataattg tgagagagat
    38761 ttttaccgaa accgaatcct gggtcgagca acaatttctc ttttgcgatg ccggccttct
    38821 cacaacgtgc tatttgctca ataaagtagc gattcacctc ggcaaagaca tcgtcatatt
    38881 tcggcgcctc ctgcatggtt ttggggttgc cctgcatgtg cataagactg accggcaagc
    38941 cggtttccgc tgccgcttcc aacgcgccgg gttcggagag tgaacggaca tcattgataa
    39001 tatgcgcgcc cgcccttgcc gcttcacgga tcacctcggg tttagaggta tccacagaaa
    39061 tccacacttc aaaacgttgc gcgattgctt ccagtaccgg aataacgcga tccagctctt
    39121 cttccacgct cacttctgcc gcgcctggtc gcgttgattc cccccccaca tcaataattg
    39181 tcgccccggt attcaccatt aaattcgcat gtttcaccgc ctcaatcagc gtgttatgcg
    39241 cgccgccgtc ggagaacgaa tccggcgtta cgttcaggat ccccataaca tgcggatgag
    39301 tgagatcgag cgtggcgccc tgagcgaaga gtttcatggt caaaatccct gttttattta
    39361 tggtgagtta aaaaaagaaa aaccccgggg caagccccag ggtttcggtg agcgctaaac
    39421 ataatgttgt aaaacaaatg cttatttgtc gcccagctgc tctgacatcg tgttgcccgg
    39481 gttcggcgtg cgtggttcat caaccggacg cggcgcctga ggcgtaccat tgctgtcaga
    39541 gttattggtg ccgtttggat cttcccagcc cgcaggcgga cgcacttcac gacgcgccat
    39601 caggtcatca atctgcggcg catcgatggt ttcatatttc atcagcgcat ctttcatcgc
    39661 gtgcagaata tccatattgt cagtcaggat ctgacgagcg cgattgtagt tacgttcaat
    39721 cagcgctttc acttcctggt cgatgatacg cgcagtttca tcagacatat gtttcgcttt
    39781 tgcgacgcta cggccgagga acacttcgcc ctcttcttcc gcgtacagca acggaccgag
    39841 tttctccgag aagccccact gggtgaccat gttacgcgcc aggttagtcg cgactttaat
    39901 gtcgttcgac gcgccggtag aaacatgctc aacgccgtag ataatctctt ccgccagacg
    39961 gccgccgtac agcgtgctga tttggctttc cagcttctga cggctggcgc tgatcgcgtc
    40021 gccttcaggc aagaagaagg tcacgcccag cgcacgacca cgcgggataa tcgtcacttt
    40081 gtgcaccgga tcgtgttccg gcaccaggcg accgataatc gcgtggcccg cttcgtggta
    40141 cgcggtcgac tctttctgcg cttccgtcat caccatggag cgacgttcgg cgcccatcat
    40201 gattttgtct ttcgctttct cgaactcaac catcgacact acgcgcttgt tgccgcgtgc
    40261 ggcaaacagc gccgcttcgt tgaccaggtt cgccaggtcc gcaccggaga agcccggcgt
    40321 accgcgcgca atgatcgccg catcaatgtc cgtcgctaac ggtacgcgac gcatatgcac
    40381 cttcagaatc tgctcacgac cgcgaacatc cggcaggcct accaccacct gacggtcaaa
    40441 acggccagga cgcagcagcg ccgggtcaag gacgtccgga cggttagttg cggcgataac
    40501 gatgatacct tcgttacctt cgaagccgtc catctcaacc agcatctggt tcaacgtctg
    40561 ctcacgttca tcgtgaccac cgcccagacc agcgccacgc tggcgaccta cggcgtcgat
    40621 ttcatcgatg aagataatgc acggtgccgc tttcttggct tgttcgaaca tgtcacgcac
    40681 acgagatgcg ccgacaccca cgaacatttc cacaaagtca gaaccggaaa tcgtaaagaa
    40741 tggcaccttc gcttcacccg caatggcttt tgccagcagg gttttaccgg tacccggcgg
    40801 gccgaccatc aggacgcctt tcggaatttt accgcccagc ttctggaaac ggctcggttc
    40861 acgcaggtat tcaaccagtt ccgccacttc ttctttcgct tcgtcacaac ccgcaacgtc
    40921 agcaaacgtg gttttgatct gatcttccgt cagcatacgc gccttgctct taccgaacga
    40981 catggcgcct ttgccaccgc cgccctgcat ctgacgcatg aagaagatcc agacgccgat
    41041 cagcaacagc atcgggaacc aggagatgaa gatagaagcc agcaggcttg gctcttcagg
    41101 tggttcgcca acaaccttga cgtttttagt cagcaggtta tcaagcagct tcggatcatt
    41161 aatcggaatg taagtcgtgt aacggttact atctttcttg gtaacgttga tctcacgtcc
    41221 gttgatacgc gcttcgcgaa cctggtcctg attgacctct tgcaggaagg tagagtaatc
    41281 caccttacgg ccattagact cgctgggccc aaagctctgg aatactgaca tcagcacaac
    41341 ggcaatgacc agccagagta ttaggttttt cgccatgtca ctcaagggat taacctctta
    41401 ttacaactgt gttaaaaaca gcgtcaggat actctatatc cagtttcttt caaaccttac
    41461 gtctgaaatc tgccggttat cactttcgcc cggtcgctac aatgtacact tcacgcgaac
    41521 gcgcgcgcga agagtccggc ttacgaactt taaccttcgt aaacagggag cgaatttccc
    41581 ttagatactc atcgaaacct tcgccctgga acaccttcac tacaaaactt ccgcctggcg
    41641 ccagcacatc gcggcacata tctaacgcca gctccaccag atacatggcg cgggggatat
    41701 ccaccgccgg tgttccgctc atgtttggtg ccatatccga catgacaact tgtactttac
    41761 tgtcacccac gcgttccagt aacgctttca tgacaagttc atcacgaaaa tcgccctgaa
    41821 gaaagtccac accaacgata ggatccatag gtaaaagatc acaagcgatg atgcggcctt
    41881 tgccgccaat ctgcgtgacc acatactgtg accaccctcc tggcgcagcg ccgagatcga
    41941 ctaccgtcat tcccggctta aaaagtttgt cactttgctg tatttcatca agtttaaacc
    42001 aggcacggga gcgtagcccc tttttctgcg cctgttgaac atatttatcg ctaaagtgtt
    42061 cctgaagcca gcggcttgag ctggcagaac gctttttacc tgtcatttaa ctttcccgtc
    42121 ggggcagttc atcgtagcca atggcgtaaa tttctacacg cctatttggc gatataaggg
    42181 agatggcggt agaatgaccc gttttcaatc ccaacgtaag caaaaatata cgatgaatct
    42241 gagtactaaa caaaaacagc acctaaaagg tctggcacat ccgctcaagc ctgttgttat
    42301 gcttggcaat aatggtttga ccgaaggggt actggccgag attgaacaag cgttagagca
    42361 ccatgaactt atcaaggtga aaatcgcctc ggaagatcgc gaaacaaaaa ccttgatcgt
    42421 ggacgctatc gtgcgcgaaa ccggcgcctg taacgtacag gtcatcggta aaacgctggt
    42481 gctgtatcgc ccaactaaag agcgtaaaat ctcgctgccg cgttaaggat atcctaaagt
    42541 cgaacacaaa atctgtgtaa aacgaggggt tttccacgag caggagagca aaatgccacg
    42601 ctctctccgt tgataaaagg ccgctatgcg gcctttttcc tttctttaca atacaccaac
    42661 aatttgcgta ttgagtactg cttaaaggta ttccacttta agcacttcgt attccacatc
    42721 gccgccaggc gttttgatca ccacgacgtc atcctgctct ttgccaatca ggccgcgagc
    42781 gattggcgag tttaccgaaa tgagattttg cttaaaatcc gcctcatcat cgccaacaat
    42841 acgataggtc tgctcttcgt cggtgtccag gttcagcacc gtgacggtag cgccgaaaat
    42901 cacgcgacca ttgttcggca ttttggtgac gtcaatcacc tgcgcattcg acagttttgc
    42961 ttcgatatct ttaatgcgcc cttcgcagaa accctgctgt tcgcgtgcag catgatactc
    43021 cgcgttttct tttaaatcgc catgttcgcg cgcttcggcg atagcggcga tgatttcagg
    43081 acggcgcaca gatttcagaa aatccagctc ttcgcgcagt ttttcggctc cgcgtaaggt
    43141 catcggaata gcttgcattt gttatacctc ttgaacattc ctgtaggggg caatgaactc
    43201 taccccggct gctaagccag ccccggcata tgccatacca gggtcagaag caaaaaaaca
    43261 ccaacccggg cgcgcagtcc caggtcagct acaatttcct ctttgataac cattttaccc
    43321 tggagttccc tatgggtcat cgtttacttt ttagggcgtt gcgccgtagt atgacggctt
    43381 gtttccaggg tgttagcgcg agattatgcg attttccaga tttatcatcg gattgaccac
    43441 cagtatagcg ttcagcgttc aggccgcgaa tattgacgaa tacatcaaac agcttccggc
    43501 cggcgccaac ctcgcgctga tggtgcaaaa gattggcgcg cccgcgccgg ctattgatta
    43561 tcatagtcag cagatggcgc ttcccgccag tacccaaaag gtgattaccg cgctggcggc
    43621 gctgattcaa ctcggcccgg atttccgttt tacgaccacg ctggagacta aaggcaacgt
    43681 cgataacggc atcctgaaag gtgacttaat tgcgcgattc ggtggcgatc caacgctaag
    43741 acgtcaggat attcgcaata tggtcgcgac gctgaaaaag tcaggcgtca cgcaaatcga
    43801 cggcaatgtg cttatcgaca cgtcgatttt cgccagccac gataaagcgc caggctggcc
    43861 gtggaacgac ctgacgcagt gtttcagcgc gcctcccgcc gccgccattg ttgaccgcaa
    43921 ctgtttttct gtgtcgcttt atagcgcgca aaaaccaaac gatttagctt ttattcgcgt
    43981 ggcctcttat tatccggtaa cgatgttcag ccaggtacgg actctgccgc gcggttcggc
    44041 agacgcgcag tattgcgagc tggatgttgt gcctggcgat ttgaaccgtt atacgcttac
    44101 cggctgttta ccacagcgcg ccgacccgct gccgctggcc tttgctattc aggacggcgc
    44161 cagctacgcg ggcgcgatcc tcaagcagga actgaaagag gccgggataa cttaccgcgg
    44221 cacgctgctg cgccagacgc aggttaacga gcccggaacg atcgtcgcca gtaaacagtc
    44281 ggcgccactg cacgatctgc ttaagattat gctgaaaaag tcagacaaca tgatcgccga
    44341 tactgttttt cggatgattg gtcatgtcag gtttaacgtg cctggcacct ggcgggcggg
    44401 atcggatgct gttcgccaga tcctgcgcca acaggcggga attgatatcg gcaataccat
    44461 tattgccgac ggttccggtc tttctcgcca taacctgatc gctcccgcca cgatgatgca
    44521 ggtgctgcaa tatatcgccc aacacgataa cgagctgaac tttatctcta tgctgccgct
    44581 ggcgggctat gacggttcat tgcaataccg cgccggccta catcaggcgg gcgtagacgg
    44641 taaggtttcg gcgaaaaccg ggtcactgca gggcgtgtac aacctggcgg gctttattac
    44701 caccgcaagc gggcagcgga tggcatttgt acagtatttg tccggctacg cggttccacc
    44761 tgccgatcag cgtaatcgac gtattccgct ggtacgcttc gagagtcgat tgtacaagga
    44821 tatttatcag aataactgag tgcattattg ccggatggcg gcgctaacgc gtcttatccg
    44881 gcctacaaag aacataataa aacgggccgc aaatgcggcc cgttggcttt tgtaggccgg
    44941 ataagcgtaa gcgccatccg gctacgagat taacgtttgt agatgaactc gacgccttct
    45001 tcgtcgtctt catcccagtc gtcatcccag tcatcgtctg cgtcttcttc cacttcagcc
    45061 aactgctggc gatgataatc gtcccacatg aactcgactt tttccggctg ttttgcttct
    45121 tcagcctgcg cgatcggatt ctcgatgata aaggtcatca catcccagca gagatctttc
    45181 acccctagct gactggcagc ggaaatcaga tagtatttcc cttcccagcc caacgcttcg
    45241 gcgatcgctt tcgctttctc ttccgcttcg gatttatcca tcagatcgat cttgttgaac
    45301 actaaccagc gcggtttagc cgccagatcc tggctgtatt tttccagttc gccaataatg
    45361 atacgggcgt tttccaccgg atcggaacca tcgatcggat cgatatcaat gaggtgcagc
    45421 agtacgcggc aacgttcgag gtgcttcaag aagcgaatcc ccaggcccgc gccttccgcc
    45481 gcgccttcga tcaaccccgg aatgtcggcc accacaaaac tcttttcgct gtccatacgt
    45541 accacgccca ggctcggcac cagcgtggta aacggatagt ccgcgacttt cggttttgct
    45601 gccgataccg cgcgaatgaa cgttgattta ccggcatttg gcatccccag catcccgaca
    45661 tccgccagca gcatcagttc cagcagcagg tcgcgcttat cgcccggcgt accattggtt
    45721 ttctggcgcg gcgtacggtt aaccgaggat ttaaaacggg tattgcctaa cccatgccag
    45781 ccgcccttcg cgaccaacag acgctgaccg tgtttggtca tgtcgcccat cgtttcaccg
    45841 gttccttggt cgataacgcg cgtaccgacc ggcactttga tggtcacgtc tttaccgcgt
    45901 ttaccggtac agtcgcggct cgcgccattc tgaccacgtt cagcgcggaa cgatttttca
    45961 aagcggtaat cgatcagcgt attcaggttt tcatcggctt ccatccagac gtcgccgccg
    46021 tcgccgccat caccgccgtc cgggccgcct ttcgggatat atttttcgcg gcggaagctc
    46081 acacagccat taccgccatc gcctgcaacg accagaatcg atgcttcatc aacaaacttc
    46141 attttattct ccgtaaatca ttcgcctgag cggggttgcg aaaccaccgt ttcatgcttg
    46201 cgtaaaccgc cccaaatacg atgaccaatg gcggaataca tcgcgcccgc aaccacgaca
    46261 aacgcaccga gataacctaa aaggtttaac atcggtctgg cgaagaaatc gggccaggcc
    46321 atagataaaa gatctgaaaa cagcaggata aatagcggtg taagcgtgat tatcgcgctc
    46381 acctgcgccg cctgccaacg cgccatcgct tccgccaggg cgccatatcc taccagcgta
    46441 tttagcccgc agaaaatcaa acaggcgagc tgccagtcgc tcagttgcgc tatcaccatc
    46501 ggttttgcca acggcaaaag cgctatcgta cataaagtgt acagtaaaaa caggatctgc
    46561 tgcgaggcca gacgtcgcaa taatactttt tgcgccacgc catagctcac ccacaccatc
    46621 gccgcgccta cgccaaaaat aacgccccag gtgtagtcgg tcagtcgggt aaaaatctcg
    46681 atcagactgg tgttaaaaaa cattaccagc ccgctcaata acatcagcgc gccaatcacc
    46741 tgcgtaccgc gcatcttttc tttcagaata aagacgctgg cgaccatcat gccaaccggc
    46801 gagagctggc cgataacctg cgacgcggtt gggcttaaat attgcaggga agaactgaac
    46861 aaaatgaaat taccgaacag tccgcaggtc gctatcgcca ataacaccaa ccagcgcggc
    46921 ttacgaaaaa tacgcagcgg cggcagcttt ctttttactg ccagtatcgc cccgaggcca
    46981 atactggcca ttaagaagcg gtagaagaca atggttgaag gctccatcac ctccagcact
    47041 tgcttcattg ctattggcaa cgctccccag cacatcgcgg tagtgagcgc taaaagaatg
    47101 ccaatgcctg cctgctgctt catgccgtgt tccctgcaaa gacccgttaa cggcattcac
    47161 acagccacac gggtatattt tagtcggcca tcgaatgtaa aaagccccgc aacaggtgcg
    47221 gggctttcat ccgttaccgg accacaaaaa acttactcag caacgatgct gatgtattta
    47281 cggtttttcg ggcctttaac ttcgaatttc actttaccgt ctgctttagc aaacagagtg
    47341 tggtcacgac cgcaaccaac gttggtgcca gcgtggaatt tagtaccacg ttgacgaacg
    47401 atgatgctgc ctgccagaac tgcttcaccg ccaaagcgtt ttacgcccag acgtttagct
    47461 tcagaatcgc gaccgttacg agtcgagccg ccagcctttt tatgtgccat ttaatctgct
    47521 cccctaatct taagcgctga tgccggtaat tttcacatca gtgaaccact gacgatggcc
    47581 ctgctgctta cggtagtgtt tacggcgacg aaacttaacg attttaactt tctcgccacg
    47641 accgtgggca acaacttcag ctttgattac gccgccatca acgaaaggaa cgccgatttt
    47701 gacttcttca ccgtttgcga tcatcagaac ttcagcgaac tcgatagttt cgccagttgc
    47761 gatgtccagc ttttccaggc gaacggtctg accttcgctt actcggtgtt gtttaccacc
    47821 actttggaaa accgcgtaca taaaaaactc cgcttccgcg cacacctttc aatgattcag
    47881 agcgcgctat aaatattcac aatagggcgc gaatattacg caaattgcac ggctttgaca
    47941 agtgctacca tcaatacatg aagaaaaaaa aacacaacgc atacggtaac gtttatctgc
    48001 ggcgtttttt cagtacaatc agggtatatt tctaaccata aaccctacgt tacctcattc
    48061 agacatggga taatcggagc gataagcccg gcttttgcga tgaatttaga aaaaatcaac
    48121 gagttaaccg cgcaagatat ggcgggtgtc aatgcgacaa tccttgaaca gcttaattcc
    48181 gacgttcaac tgattaatca gctaggatat tacattatta gcggcggcgg aaaacgcatt
    48241 cgtccgatga ttgccgttct tgccgcgcgt gcggtgggtt atcagggtaa cgcgcacgtg
    48301 actatcgccg ctctgatcga gtttatccac acggcgacgc tgctacatga tgatgtggtg
    48361 gatgaatctg atatgcgtcg cggcaaagcg acggcaaatg ccgctttcgg taatgccgcc
    48421 agcgtgttgg tcggcgactt tatctatacc cgcgccttcc agatgatgac cagcctcggc
    48481 tcgttaaaag tgctggaagt gatgtcggaa gcggtcaatg tgattgcaga aggcgaagtg
    48541 ctgcaattga tgaacgtgaa tgacccggac attaccgaag aaaattacat gcgggtgatt
    48601 tacagtaaaa cggcccgtct gttcgaagcc gccgcccagt gctccggtat tcttgccggt
    48661 tgtacgcctg agcaagagaa agggttgcag gactatggcc gctaccttgg tacggctttc
    48721 cagctcattg acgatctgct ggattacagt gccgacggcg agcatctcgg taaaaatgtg
    48781 ggtgatgacc tcaatgaggg caaacctacc ttaccgttgc ttcacgccat gcgccacggt
    48841 acgccagaac agtcagcgat gatccgtacc gctattgaac aaggtaatgg ccgtcatctt
    48901 ctggaaccgg ttctggaagc gatgaccacc tgcggctcgc tggaatggac gcgtcagcga
    48961 gcggaagaag aagccgacaa agcgatatcc gcgttgcaga tattgccgga taccccatgg
    49021 cgtgaggcgc taatcggtct cgcacacatc gcggtgcagc gcgatcgttg atgccattct
    49081 cttatcccgc gcactgcgcg ggatatccca ttaagttcta ataaactcca gataccctat
    49141 tgcctgtctt ttcgtatatt catatacggc ttcccctggc atattctgaa tattgccgcc
    49201 acttacatga actttttaga acattccttc acgaagcgtt atagtatcga acgtcgtcgg
    49261 gttgttaaaa ccgtaagtga ttaatctaag gagtgatgga tgtatggaaa gcaagcttat
    49321 tgactggcat ccggccgata tcattgccgg actacgtaaa aaagggactt caatggccgc
    49381 tgagtcacgc cggaatggat tgagttcatc cacgctggcc aatgcattaa cgcgcccgtg
    49441 gccgaaagga gagttgatta tcgcgaaagc attgggaacg gaaccctggg ttatttggcc
    49501 atcgcgttat cacgatccgc gcacgcatga gtttatcgac agaacgcggc ttatgagagc
    49561 gcgtaataaa gacaaacaga atgtagagta agtgcctgta aaacaacccc cgcaatcgcg
    49621 ttcgcggggg ttattcagcg tacagaaggt tattcgcctt tcacgcgttc aatattcgcg
    49681 cctagcgcgc gcagtttgtc ttcgatgcgc tcataaccgc gatcgatgtg ataaatgcga
    49741 tccacaatcg tcgtgccttc cgcaatacag cccgccagca ccaggctcgc agatgcccgc
    49801 agatctgtcg ccatgacctg ggcgccagag agcgtttcta cgccatggca tatgacggta
    49861 ttgctttcaa tttccgcacg cgcgcccatg cggctgagtt caggcacgtg cataaaacgg
    49921 ttttcaaaga cggtttcagt gataaagccc gtcccttccg ccaccaggtt cagcaacgtg
    49981 aactgcgcct gcatatcggt cgggaatgcc gggtgcggcg ctgtacggac attgaccgct
    50041 ttcggtcgtt tgccgtgcat gtccagacta atccagtcct cgcccacttc gatatccgcg
    50101 ccagcatcgc gcagtttcgc cagtaccgcg tccagagtgt ccggttgcgc gttacggcag
    50161 aggattttgc cgcgagagat cgctgccgcc accaggaaag tccccgtttc gatacgatcc
    50221 ggcagcacac gataaacgcc gccgcccaga cgctctacgc cctcgatcgt aatacgatcg
    50281 gtgccctgcc cggcgatctt cgcccccagc gtaactagga agttagcggt gtcgacaatt
    50341 tccggctcgc gcgcggcgtt ttcaatgatg gtcgtccctt ccgccagcgt agcggcgcac
    50401 ataatggtga cggtcgcgcc gacgctgacc ttatccatca cgatatgcgc ccctttaaga
    50461 cgtccttcga cggaggcctt tacgtagccc tcttctagct tgatggtcgc acccagttgt
    50521 tccagaccgg taatatgtag atcaaccgga cgcgcgccga tagtacagcc ccccggcaga
    50581 gagacttgtc cctgaccaaa acgggcaacc agcggcccca gcgcccatat cgaggcgcgc
    50641 atggtcttaa ccagatcata aggcgcgcag aacacgttca cctggctggc gtcaatgtgt
    50701 accgatccat tgcgttccac tttcgcgcct aattggctca ggagcttcat cgacgtatcc
    50761 acgtctttca gttttggaac gttttggatc tctaccggtt cttctgccag cagagcggcg
    50821 aacaggatcg gcagcgcggc gtttttggcg ccggaaattg tgacttcgcc ctggagcgtc
    50881 gttggcccct gtacacgaaa tttatccatt attgtattct cagttaagca ttcatctccg
    50941 ctaccggcag gttacccgta gcttaaaatc cgttaagttt acgatcgcgc gcccattccg
    51001 ccggggtata tgctttgatc gatacggcat ggatacggtt gtccgcaatg tactccatta
    51061 gcggcccata gaccgtttgc tgtttcttga cccggctcat gccgtcaaac atctcgccca
    51121 cggcaataac ctgaaagtga ctgccatcgc cggagacgtg gacttcctgg agggagaggg
    51181 cattcatcag cacactctga atttcatgat tttccatggg ttctttattc gtcaaatagt
    51241 gaaaacagcc caacatctta gagcaaagtc gcgccgtctt aaataagcaa aagattacgc
    51301 tgataaatca gcgcggtaaa agtgccggat ggtgctgcta acgcaattta tccggcctac
    51361 ggggatcatg cgaagtgtag gccggataaa ccatccggca ttcattacat acggggaagt
    51421 acgtcttcag gcaagttata taattgcgcc agcgcgtaaa ccttgtcgtt aacgccagac
    51481 agcgacacgg cattgccctg cttttttgcc tggttcacaa ggtgcgccag cagcgccagt
    51541 ccccccgtat ctaccctgga gatctggctc aggtcgatac gggtaacgcc attcatcgct
    51601 tctacgcgcg cgtcccatag cggcgccaac acgtcctgat ccagctctcc cgccagcacc
    51661 agagtgtccg cctcacgcgt ccaggtgagt tgcggcgtca ttactgtttc tcgtccaaag
    51721 taattttctg ttgagagata gatttcagtt gtgcggtcag gccgtcgatg cctttagtac
    51781 gcagcagatc gctccactca ttttgcttgg tggtgatcat gctgacgcct tccgcaatca
    51841 tgtcatacgc ctgccagttg ccggtctgag tgtttttgcg ccactggaaa tccaggcgta
    51901 ccggcggacg accgttggga tcgataatcg ttacacggat aggcacaatg gtcgcatcgc
    51961 ccagcggttg ctcaggcgct atctggtaag tctggccgtg gtacatcgcc agcgcctgac
    52021 cgtatgcctg tttcaggtat tcgcgaaacg ctgcaaaata ggcttcacgc tgcgccgggg
    52081 tcgcctcttt gtagtagcgg cccaacacca gcgcgccggc atattttacc tgcacgtacg
    52141 gcagaagttc ctgatcaaca acgtctcgca ggtaatccgg attggcacga attttcggct
    52201 gttcgttttt caggcgatca aaagttttct gcgccgcctc gttcatcagt ttataaggat
    52261 tgctctgatc cgctgccgtt gctgcgctta atggcgcaat gaccagcagg gccaccatca
    52321 tcagtcgttt aaacatgcct caattctcct gagattattt cgtttcgccc gcgggcgttg
    52381 tggcttcagt atggccttcc gttgcggctg gcgcatcgcc agaattctta ttgtcgtcgc
    52441 ctttgctgtt ataaaggaac tggccaatca tatcttccag caccattgca gacttggtgt
    52501 cctgaatcgt actcccatct ttgaggatag acgttcccag ctcaggatct tcaaaaccga
    52561 cgtttaatgc cagatattgc tcccccagca gcccggaagt acgaatactc aacgagctgg
    52621 tatcgggaat atggttataa cgctcttcga tgtcgagcgt tacgcgcggc aggtatgttt
    52681 tcggatcaag cgagatatct tcaacccgcc cgacaaccac cccgccgatg cgtaccgggg
    52741 aacgcacttt cagaccgccg atgttatcga aggtcgcata aaccttatag gtcggctccg
    52801 tgcgcataga ggtcacattt gccgccttca ggcaaacaaa cagcgccgcc agcaacgcta
    52861 ccagcaaaaa aacgcctacc caaatttcat tttttttcgt ttgcatgaac tcaattccca
    52921 aacatcagtg cggtcagcac aaaatccagc cccagaacgg ccaacgatgc gtgaaccacg
    52981 gtacgcgtcg ttgcccggct aatcccggca gaagtcggta ttgcgtcata accgttgaat
    53041 aacgcaatcc atgttaccgt aatggcgaac accacgctct ttatcagaca gttcaccagg
    53101 tccatacgcc agtcgacggc attctgcatc gcggaccaga agaacccggc gtcgattccc
    53161 ttccagctta cgccgaccag cgagccgccc cagataccga ccgccacaaa gataatggtc
    53221 agtagcggca atgaaatcac gcccgcccaa aagcgcggcg aaatcacccg gcgcaatgga
    53281 tcgaccgcca tcatctccat actggagagc tgctccgtcg cccgcatcag gccgatttcc
    53341 gccgtcaacg ccgacccggc ccgcccggca aacagcaacg ccgcgaccac cggccccagc
    53401 tcgcgcagca gcgaaagcgc cactaacatg ccaagactgg tctccgcgct gtaagtggtc
    53461 agaaccagat agccttgcag ccccagcacc ataccgatga atacgccgga gacaataatg
    53521 ataagcatcg acaagacgcc cacattataa agctggcgca ccagcagcgg cgcatgtttg
    53581 cgaaactccg gcttaccgat aatcgcattg aataacatta acccggcgcg cccgaacgtc
    53641 ctgacggttt tgatcccgct gtgtccgagt gctgccagcg catttaacag catgagtggc
    53701 ttaactccct gtttcgagta aatcaaggtg atagtcgccc gccggatagc ggaacggaac
    53761 cggcccgtcg gcaataccgt caaggaactg acgcacgcgc gggtccgtat tctcctgcaa
    53821 cgcctgagcg ctaccgtgag cgacgatttt tttgtccgcc atgatccagg cgtgatccgc
    53881 aatactgagc acctctggca catcatgcga gaccaccacg caggtcacgc ccagcgcgct
    53941 gttcaattct gaaatcagct tcaccagaac gcccatggta atcgggtcct ggccaacaaa
    54001 cggctcatcg aacatgatga gatccggttc cagagcgatg gcgcgcgcca acgcggcgcg
    54061 gcgcgccatc ccaccggaga gctcggaagg catcagtttt gccgcgccgc gcagcccgac
    54121 agcttccagt ttcatcatca cgacgctttt tagcagcggc gcgggtaaat tggtgtgctc
    54181 ccgtagcgga taggccacat tgtcaaacac gttcatgtcg gtaaacagcg ctcccgactg
    54241 aaacagcata ctcatacgtt tacggacggt gtagagccgc gaacgggaca tggccggcac
    54301 attctcgcca tcaaataaga tctcgccctt atccggcggg atctgtccgc caatcaggcg
    54361 caacagcgtg gttttaccga tgcccgacgg ccccatgatc gccgtgatct tcccgcgcgg
    54421 caccgtcagg gaaatattat cgaaaatgca gcgttcgcca cggcaaaagc tgacgtcgcg
    54481 catatcgact aaattggccg cagactgacc cattgattca tccttcgtat tgccttgttg
    54541 aggtaaccat ggcgctgaat ttaaccatgg gttcgacata attacagaat attaactgac
    54601 agggttagcg aaagctggca ttcgttttac tttttagccg cataaagtca aaattaggac
    54661 ttcgttacgg cttccagata tcccttccag gggaccggcg agtatacctg aagaaaggac
    54721 tttagatgct tttagcgatg gcgctactca taattggttt gcttctggtg gcctacggcg
    54781 ccgatcgtct ggtgtttgcg gcctctattt tatgccgtac attcggtatt cccccgctga
    54841 tcatcgggat gacggtcgtg agtatcggca cctcgctgcc ggaaattatt gtgtcggtcg
    54901 ccgcatcgct acacggtcag ctcgatttgg ccgtcggcgc ggcgctcggt tctaacatca
    54961 ccaatatttt gctgatctta gggctggcgg cgctggttcg tccatttacc gtgcattccg
    55021 atgttctacg tcgcgaattg ccattaatgt tatttgttag cgtggtagcc ggttccgtac
    55081 tgcatgacgg acagttaagt cgcagtgatg gtatctttct cctgcttctg gctgtgctat
    55141 ggctgttatt cattgttaaa atcgcgcgtc tggccgaacg ccaggggaat gacagcctca
    55201 cccgcgaaca actggcggag ctgccgcgcg aagacgggct ccccgtcgcg ttcttatggc
    55261 tgggcattgc gctggtcatc atgccgatgg cgacgcgcat ggtaatcgat aacgctacgg
    55321 tgctggcgaa ctatttcgcc atgagtgaat taacgctcgg tctgacagtc atcgccgtcg
    55381 gcaccagtct gccagaactg gcgacggcga ttgccggcgt gcgaaaaggc gaaaatgata
    55441 ttgccgttgg taatctcatt ggcgccaata tttttaatct cgccatcgtg ctgggactgc
    55501 ctgcgctgat cgcgccgggg gagatcaacc cgctggcgtt tgggcgtgat tatagcgtga
    55561 tgttgctggt tagcgtggtt ttcgctttac tttgctggcg gcatccgcgc cagattggcc
    55621 ggggcgcagg tatactgctg accggcgggt ttatcgtatg gctggcgatg ctctattggc
    55681 tatcgccact tcttgttgga taactggaaa cggattatgt cgcatttagc gttgcaaccg
    55741 gggtttgact ttcagcaggc aggcaaagag gtcctggaaa ttgaacgtga aggcctggcg
    55801 gagcttgatc aatatatcaa ccagcatttc acgctggcct gtgaaaaaat gttcaactgc
    55861 accggaaaag tggtggtcat ggggatgggg aaatccggcc atatcggacg gaaaatggcc
    55921 gccacgttcg ccagtaccgg cacctcttcc ttttttgtac atccaggcga agccgcgcac
    55981 ggcgatttgg ggatggttac gccgcaggat gtggttatcg ctatctccaa ctccggcgaa
    56041 tccagcgaga tcgcggcgct aataccggtg cttaaacggc tgcacgtacc gttaatttgc
    56101 attaccgggc gaccggaaag cagcatggcg cgtgcggcag atgtgcatct atgtgttaaa
    56161 gtgcccaaag aagcgtgtcc gttaggcctg gcgcctacca gtagtaccac cgcaacgctg
    56221 gtgatgggcg acgcgctcgc cgtggcgttg ttaaaagcgc gcggctttac cgccgaggat
    56281 ttcgctctgt cgcatcctgg cggcgcgctg ggacgtaagc tactgctgcg cgtaagcgat
    56341 attatgcata ctggcgatga gatcccgcat gttaataaac atgccaccct gcgtgatgcg
    56401 ctgttagaaa ttacgcgtaa aaatctcggt atgaccgtca tttgcgatga atccatgaag
    56461 atcgacggta tcttcaccga cggcgattta cgtcgcatgt tcgatatggg cggcgatatg
    56521 cgccagttgg ggatcgccga ggtgatgacg ccagggggca ttcgcgtgcg tcccggtatt
    56581 ctcgctgtcg atgcgctgaa tttaatgcag tcccgccata tcacctccgt actggttgct
    56641 gatggcgacc agttactcgg tgtgttacat atgcatgatc tcctgcgtgc aggcgtcgtg
    56701 tagaaactca aggataatta acgatgagta aagcaggtgc gtcgcttgcg acctgttatg
    56761 gccccgtcag cacccatgtc atgaccaaag cggagaatat ccgcctgctc atcctggacg
    56821 tggatggcgt attgtctgac ggcctgattt atatgggcaa taacggcgaa gagctgaagg
    56881 ctttcaacgt tcgtgacggc tatggtattc gctgtgcttt gacctccaat atcgaggttg
    56941 ccattattac cggacgaaag gctaaacttg tagaagatcg ctgcgccacg ctggggattg
    57001 tccatcttta tcagggacag tcgaataagc tgatcgcctt tagcgatctg ctggaaaaac
    57061 tggccattgc gccggaaaat gttgcctatg tcggcgatga tctgattgac tggccagtga
    57121 tggaaaaagt ggggttaagc gttgccgttg cggatgcgca tccgctgctg atcccccgcg
    57181 ctgactatgt gacgcacatt gccggcgggc gcggcgcggt acgtgaggtg tgcgatttgc
    57241 tgctgctggc gcagggcaag ctggatgagg ccaaagggca atcgatatga gtaaaaccag
    57301 acgttgggtt atcattctac tgtcgctggc tattctggta ctgattggta tcaatctggc
    57361 ggataaagac gatcctgctg ccgtgatggt caacagcaac gatcccacgt ataaaagcga
    57421 gcacacggat accgtcgtgt acagtccgga aggcgcgttg agctatcgtc tgatcgcgca
    57481 gcacgttgaa tatttttccg atcaggcggt ctcatggttt acgcaaccgg tattaaccac
    57541 ctttgataag gataaagtgc cgacatggtc gatcaaggcc gataaagcca aattgactaa
    57601 cgatcggatg ctctatctgt atggccatgt tgaagtcaac gccctggtgc ctgacgctca
    57661 attacgcaga attaccaccg ataacgcgca gattaatctg gtgacgcagg atgttacctc
    57721 gaacgatctg gtgacgttat acggcacaac atttaactcc agcggactga aaatgcgcgg
    57781 taacttacgc agcaagaacg ccgagctgat tgaaaaggtt agaacctctt atgaaattca
    57841 aaacaaacaa actcagcctt aatcttatgc ttgccggctc gctgctggcc gccagcattc
    57901 cggccttcgc cgtcacgggc gataccgaac agcctattca tattgactcg gatcaacagt
    57961 cactggatat gcaaggcaac gtcgtgacct ttacgggcaa cgtggtaatg acccagggca
    58021 cgattaagat caacgccgat aaagtcgtgg ttacccgccc tggcggcgaa caggggaaag
    58081 aggtgatcga cggttacggc aatccggcca ccttctacca gatgcaggac aacggtaagc
    58141 cggtgaaagg ccacgcttcc catatgcatt acgagctggc gaaagatttt gtggtgctga
    58201 ccggcaacgc ttatctggag cagcttgaca gcaacattac cggcgacaaa atcacctacc
    58261 tggtgaaaga gcagaaaatg caggccttca gcgagaaagg caaacgcgtc accaccgttc
    58321 tggtgccgtc gcagttgcaa gacaaaaaca aaggccagac tccggcgcaa aagaagagta
    58381 actaattcgt tatggcaaca ttaactgcaa agaatctggc gaaggcctat aaaggccgtc
    58441 gcgtagtgga agatgtcagt ctgaccgtta actccgggga gattgtcggg ctgctcggtc
    58501 caaacggcgc gggtaaaacc accacctttt atatggtcgt cggtatcgtg ccgcgtgacg
    58561 cgggcaatat catcatcgat gatgaagata tcagtctgct gccgctgcac gcgcgcgcgc
    58621 gccgcggtat cggctatttg ccgcaggaag cctctatttt ccgccgtctc agcgtatttg
    58681 ataacctgat ggcggtactg caaattcgtg acgatttgac cgcagaacag cgagaagacc
    58741 gcgccaacga gctgatggaa gagtttcata tcgagcatct gcgcgacagc atgggacagg
    58801 cgctgtccgg tggtgaacgc cgtcgtgtag aaatagcccg cgcgttggcc gctaatccca
    58861 aatttatcct gctggatgaa ccctttgccg gcgtcgaccc gatttccgtt atcgacataa
    58921 aacgcattat cgagcatctg cgcgatagtg ggctcggcgt gctgatcacc gaccataacg
    58981 tccgtgagac gctggcagtc tgtgaacgtg cctatatcgt gagccagggc caccttattg
    59041 cccacggtac gccgacagaa atcctgcaag acgaacacgt taagcgtgta tatcttgggg
    59101 aagacttcag actctgatag ggtagagggc tatgctgctc tagcgggaga aaacgactct
    59161 gaatatgaag caaggtttgc aactcaggct tagccaacaa ctggcgatga cgcctcagct
    59221 acaacaggcc atccgtctgt tgcagttgtc tacgctggaa cttcagcagg aactccagca
    59281 agcgctggaa aataacccgc tgcttgagca aaccgatctt catgacgaaa tcgacactca
    59341 gcaacctcag gatgacgatc ctctcgatac cgccgacgcg ctcgaacaaa aagagatgcc
    59401 ggaagagctg ccgcttgacg ccagttggga tgaaatttac accgccggga cgccgtccgg
    59461 ccccagcggc gattatatcg acgatgagct gcccgtctat cagggcgaaa cgacgcagtc
    59521 gttgcaggat tatctgatgt ggcaggttga gctaacgccc ttctcggaca ccgatcgcgc
    59581 tattgcgaca tccattgtcg acgcggtaga tgataccggc tatctcaccg tatccctgga
    59641 cgaaattcgc gaaagcatgg gcgatgtaga ggtggatctc gatgaggtcg aagccgtcct
    59701 gaagcgtatt cagcgttttg atccggtagg cgtcgcggca aaagatcttc gcgactgtct
    59761 gctgatccag ctttcacaat tcgacaaatc cacgccgtgg ctggaagagg cgcggcttat
    59821 tatctgcgat caccttgatc tgctggccaa ccacgatttc cgcacgttga tgcgcgttac
    59881 ccgactaaaa gaagaggtgc tgaaagaggc ggtaaacctg attcagtcgc tcgatcccag
    59941 acccggtcaa tcgatccaga ccggcgagcc ggagtacgtt atcccggatg tgctggtacg
    60001 caagcataac ggtcgctgga cggtggagct taatagcgac agtattcccc gtttacagat
    60061 taaccagcac tatgccgcca tgtgcaatag cgcgcgcaac gatgccgaca gccagttcat
    60121 ccgcagtaat ttacaggatg cgaaatggct gataaaaagc cttgaaagcc gtaacgacac
    60181 gctgctgcgc gtcagtcgct gcatcgtcga gcaacagcaa gccttttttg aacagggcga
    60241 agaatatatg aaaccgatgg tactggcgga tatcgcccag gccgtcgaga tgcacgaatc
    60301 cactatatcc cgcgtgacca cgcagaagta tttgcacagc ccgcgcggta tttttgaact
    60361 caaatatttc ttttccagcc acgtcaatac cgaaggcgga ggcgaagcct cttccaccgc
    60421 gattcgcgcg ctggtgaaga agttaattgc ggcggaaaac cccgcgaaac cactgagcga
    60481 cagcaagtta acctctctgc tgtcagaaca aggtatcatg gtggcacgcc gcactgttgc
    60541 gaagtaccga gagtctttat ccattccgcc gtcaaaccaa cgcaaacagc tggtttgacc
    60601 caaccgataa ggaagacact atgcagctca atatcaccgg acataacgtc gaaattactg
    60661 aagccctgcg tgaatttgtg acgacgaaat tcgccaaact tgaacagtat tttgagcgga
    60721 ttaatcaggt atacgtggtg ttgaaagtgg agaaggtcac gcacatctcg gatgcgacgc
    60781 tacacgttaa cggcggcgaa attcacgcca gcgcggaagg ccaggatatg tatgccgcca
    60841 ttgacggctt gattgataaa ctggcaaggc agttaaccaa gcataaagat aaactgaaac
    60901 aatactaatt gtccgggcag ttagccagtg caggacggcc tgttgtgtga cacaacgggc
    60961 catttgtaca gttagcgctc cgaacctggc catcaacctg acaggacagg ttcttaggtg
    61021 aaattatgat aaataacgat acgactctac aactgagcag tgtacttaac caggagtgta
    61081 cgcgtagcgg cgttcattgt cagagtaaga aacgcgcgct ggaaatcatc agcgaactgg
    61141 cggcaaaaca gctcagttta cctcctcagg tcgtgtttga agccattctg acacgcgaaa
    61201 aaatgggcag taccggtatt ggtaatggta tcgccatccc gcacgggaaa ctggaagaag
    61261 ataccttacg cgccgtcggc gtgttcgttc agctcgaaac gccgatcgcg ttcgacgcca
    61321 tcgataacca gccggtcgat ctcctcttcg ctctgctggt gcccgccgat caaactaaaa
    61381 cgcatctgca cacgctgtcg ctggtggcga aacgtctggc ggataaaacg atctgccgcc
    61441 gcctgcgcgc ggcgctgaat gatgaagagc tgtatcaaat cattactgac accgaaggtg
    61501 agcagaatga ggcataacaa ctcaatggca tttatttctg tcgttgtgag gagaaacggt
    61561 acatggtact gatgatcgtc agcgggcgtt ccggatcagg taaatctgtc gctctgcgcg
    61621 cgctggaaga tatgggattt tactgcgtgg ataacctccc cgtcgtgctg ttgcccgatc
    61681 tggcgcgaac gctggccgat cgccagattt ccgccgccgt cagcattgat gtgcgcaata
    61741 tacctgaatc acctgagatt tttgaacagg cgatgaataa tctgcctggc gctttctcgc
    61801 cgcaattgct gtttcttgat gccgaccgca ataccttgat tcgccgctac agcgacacgc
    61861 gccgtttgca tccgctttcc agcaaaaatc tttctttgga gagtgcgatc gataaagaga
    61921 gtgacttgct ggagccgtta cgctcacgtg cggatctgat cgtcgacact tcagaaatgt
    61981 ccgtccatga gctggcggag atgctgcgta cccggctatt gggcaaacgc gagcgcgaac
    62041 tgacgatggt atttgagtcc ttcggcttta aacatggtat cccgattgat gcggactatg
    62101 tgtttgatgt ccgctttctg cccaacccac actgggaccc aaaactgcgc cccatgaccg
    62161 ggcttgataa gccggtagcc gcgtttcttg accgacacac agaagttcac aattttatct
    62221 atcagactcg cagctatctt gagctatggt taccgatgct ggagaccaac aaccgcagct
    62281 accttaccgt cgctatcggt tgtaccggcg ggaaacaccg ttcggtgtat attgcagaac
    62341 agctggcaga ctacttccgc tcgcgcggta aaaatgtcca gtctcgccat cgcacgctgg
    62401 aaaaacgcaa aacatgaccg taaagcaaac tgttgaagtc accaataagc tgggcatgca
    62461 tgcccggcct gccatgaagc ttttcgaact gatgcagggt tttgacgccg aggtgctatt
    62521 acgcaatgac gaaggcaccg aagcggaagc aaacagcgtc atcgctctgt taatgctcga
    62581 ctccgccaaa gggcgtcaga tcgaaattga agccaccggc ccgcaagaag ttgaagcgct
    62641 ggcggcggtt atcgcgctgt tcaattccgg ctttgacgaa gactaaacct ccccctctat
    62701 accctattta ccccaacgcc gtcccggtat ttgatggcag tccccccaaa acc
//
LOCUS       DAJVKX010000004        62617 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000004 DAJVKX010000000
VERSION     DAJVKX010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 62617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62617
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.004"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(29..1267)
                     /gene="alaC"
                     /locus_tag="OPY25_000239"
     CDS             complement(29..1267)
                     /gene="alaC"
                     /locus_tag="OPY25_000239"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HCS0925964.1"
                     /translation="MADSRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISHWYQERYDVDIDPETEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEQYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAVRGIKT
                     MFRADGVLPSHPKPVEASTE"
     gene            complement(1990..2955)
                     /gene="glk"
                     /locus_tag="OPY25_000240"
     CDS             complement(1990..2955)
                     /gene="glk"
                     /locus_tag="OPY25_000240"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HCS0925965.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     VRVYLDEHGVSVEDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGGEPVDGKPIAVYGAGTGLGVAHLVHVDKRWISLPGEGGH
                     VDFAPNSEEEAMILEILRAEIGHVSAERVLSGPGLVNLYRAIVKSDNRLPENLRPKDI
                     TERALADSCIDCRRALSLFCVIMGRFGGDLALTMGTFGGVYIAGGIVPRFLEFFKASG
                     FRGGFEDKGRFKDYVHGIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            3159..4394
                     /locus_tag="OPY25_000241"
     CDS             3159..4394
                     /locus_tag="OPY25_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HCS0925966.1"
                     /translation="MFHPRARTMLLLSLPALIIGVASSLVLIASMKVASVFQQFLWQR
                     LPASIGIAYDSPFWIVGMLTLTGIVVGLIIRYSPGHAGPDPAIEPLISMPVSPSALPG
                     LLLALIIGLAGGVSLGPEHPIMTINIALAAAFGSRLFPRITALDWTILASAGTIGALF
                     GTPVAAALIFSQTLSGSNDIPMWDRLFAPLMAAAAGSLTTSLFFHPHFSLPIAHYTQM
                     RLVDIASGAIVAAIAIAAGMVAVWCLPRLHELLHRLKNPVLILGIGGFILGILGVIGG
                     PLTLFKGLDEMQQMAFSQTLGAGDYFTLAVVKLAALVIAAASGFRGGRIFPAVFIGAA
                     LGLMLHAHVEAVPAAITVSCAILGLVLVVTRDGWLSLFMAAVVVPDTNLLPLLCIVML
                     PAWLLLAGKPLLAANRHEP"
     gene            complement(4414..6066)
                     /locus_tag="OPY25_000242"
     CDS             complement(4414..6066)
                     /locus_tag="OPY25_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-keto acid decarboxylase family protein"
                     /protein_id="HCS0925967.1"
                     /translation="MQNPYTVADYLLDRLAGCGIGHLFGVPGDYNLQFLDHVIDHPTL
                     RWVGCANELNAAYTADGYARMSGAGALLTTFGVGELSAINGIAGSYAEYVPVLHIVGA
                     PCSAAQQRGELMHHTLGDGDFRHFYRMSQAISAASAILDEQNACFEIDRVLGEMLAAR
                     RPGYIMLPADVAKKTAIPPTEALALPVHEAQSGVETAFRYHARQCLMNSRRIALLADF
                     LAGRFGLRPLLQRWMAETPIAHATLLMGKGLFDEQHPNFVGTYSAGASSKEVRQAIED
                     ADRVICVGTRFVDTLTAGFTQQLPAERTLEIQPYASRIGETWFNLPMAQAVSTLRELC
                     LECAFAPPPTRSAGQPVRIDKGELTQESFWQTLQQCLKPGDIILVDQGTAAFGAAALS
                     LPDGAEVVVQPLWGSIGYSLPAAFGAQTACPDRRVILIIGDGAAQLTIQEMGSMLRDG
                     QAPVILLLNNDGYTVERAIHGAAQRYNDIASWNWTQIPPALNAAQQAECWRVTQAIQL
                     AEVLERLARPQRLSFIEVMLPKADLPELLRTVTRALEARNGG"
     gene            6246..7244
                     /gene="mgrA"
                     /locus_tag="OPY25_000243"
     CDS             6246..7244
                     /gene="mgrA"
                     /locus_tag="OPY25_000243"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HCS0925968.1"
                     /translation="MIYQPDENRYHTMEYRRCGRSGVKLPAISLGLWHNFGDTTRVEN
                     SRALLQRAFDLGITHFDLANNYGPPPGSAECNFGRILQEDFLPWRDELVISTKAGYTM
                     WDGPYGDWGSRKYLIASLDQSLKRMGLEYVDIFYHHRPDPETPLKETMKALDHLVRHG
                     KALYVGISNYPADLARQAIDILEDLGTPCLIHQPKYSLFERWVEDGLLTLLQEKGVGS
                     IAFSPLAGGQLTDRYLNGIPEDSRAASGSRFLKPEQITADKLEKVRRLNELAARRGQK
                     LSQMALAWVLRNDNVTSVLIGASKPSQIEDAVGMLANRRFSAAECAEIDAILEGRF"
     gene            7358..7684
                     /locus_tag="OPY25_000244"
     CDS             7358..7684
                     /locus_tag="OPY25_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HCS0925969.1"
                     /translation="MFRSLILAAALLAFTPLAANAGEITLLPSIKLQIGDRDDYGNYW
                     DGGRWRDRDYWHNHYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGRGR
                     GHKHHH"
     gene            complement(7745..8986)
                     /locus_tag="OPY25_000245"
     CDS             complement(7745..8986)
                     /locus_tag="OPY25_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCS0925970.1"
                     /translation="MTDNRVENSSGRAARKLRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELFFSQPDMAQLGKGMVIPALPNPEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGTRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGIADLDQAY
                     LTLEPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFHIPLWVRRTITMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSNATLMGELVNTRRVKQIGWI
                     IVVLVVALNIWLLVGTVMGLS"
     gene            9329..10531
                     /gene="nupC"
                     /locus_tag="OPY25_000246"
     CDS             9329..10531
                     /gene="nupC"
                     /locus_tag="OPY25_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HCS0925971.1"
                     /translation="MDRVLHFVLALAVVAVLALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVVIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     MSRNRMYTMAATAMSTVSMSIVGAYMTMLDPKYVVAALVLNMFSTFIVLSLINPYTVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIIAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPVAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAIKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            complement(10584..12773)
                     /locus_tag="OPY25_000247"
     CDS             complement(10584..12773)
                     /locus_tag="OPY25_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HCS0925972.1"
                     /translation="MPDKCNVLKNIKIFLLAFCLTVPAILLSRLISPRATIDSSYIFL
                     AWLPLCVMFSVLFLFGRRGVAPMVGGMMLTNEWNFHLPLPQAMVLLFCQTFPVLLVCA
                     IVRWQLGARWRYGIPNQGIWLRVFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTG
                     TAIFSIVDLLSLISAALIFTLFFYYPLRMIVSPHYMRIFWRRDVAPYLAKEKRLFTLL
                     WFATLATLLAVLCTPFETKYIAGYLVPVLFIGFTIGVGKISYPLLNFSWALTALFLLS
                     YNRNFLQGVGSEYSLAFILSVLISFSICLLYMARINQRSEWLNRQWHSQALTDPLTQL
                     PNLRALGQFLLQDAGQSVCYLRMENLEFLSRHYGMQMRVHCEREVFRVLQPLLLEKEK
                     IFHLPGSELLLVLTGPETEARLQYMLNVLNNRKIYWNNTGLDMEYGASWGTFDGRQET
                     LQPLLGQLSWLAEQSCSHRRVLALTQSIEAASGQTTERVLRLQKIRQALERGALVLYA
                     QPIRDAQGKGYDEILTRLRCDDGIMMPNQFIPLIAQFNLSVRFDMQVMEALLQWLSAH
                     PSAEQGARFSVNLMPLTLLQKETASRIMQLFKRYGVPPASVIIEITEEQAFSHSEISM
                     HNINQLRKFGLKIAIDDFGTGYANYERLKRLKADIIKIDGCFVKDILTDSLDAMIVKS
                     ITDLAKAKSLSVVAEFVETPAQRDLLLQLGVHSLQGYLIGRPRPLGK"
     gene            complement(12964..13039)
                     /locus_tag="OPY25_000248"
     tRNA            complement(12964..13039)
                     /locus_tag="OPY25_000248"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13004..13006),aa:Ala,seq:ggc)
     gene            complement(13082..13157)
                     /locus_tag="OPY25_000249"
     tRNA            complement(13082..13157)
                     /locus_tag="OPY25_000249"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13122..13124),aa:Ala,seq:ggc)
     gene            13379..13741
                     /locus_tag="OPY25_000250"
     CDS             13379..13741
                     /locus_tag="OPY25_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HCS0925973.1"
                     /translation="MFKERMTPEELANLTGYSRQTINKWVRKEGWATSPKPGVQGGKA
                     RLVHVNEQVREYIRSAERSVDHHADTFTPASNASLEALLMTLAKEMTSSEQKQFTSLL
                     VREGITGLLQRLGIRDSK"
     gene            13743..14135
                     /locus_tag="OPY25_000251"
     CDS             13743..14135
                     /locus_tag="OPY25_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HCS0925974.1"
                     /translation="MKRLRSKMTTEELAECLGVARQTVNRWIREQHWKTEKFPGVKGG
                     RARLIHIDASVREFILNIPAFRKLPAFYQAEEAFAEYANATHSHAYRQIIDAVENMSA
                     QEQEKLALFLSREGIRGFLTRLGINEAD"
     gene            complement(14189..15604)
                     /gene="gltX"
                     /locus_tag="OPY25_000252"
     CDS             complement(14189..15604)
                     /gene="gltX"
                     /locus_tag="OPY25_000252"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCS0925975.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSK
                     ERLEQLREDQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQDGSVIFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALN
                     APVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEI
                     FTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDT
                     RNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVR
                     DKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALGFIAERESQQ"
     gene            15863..15938
                     /locus_tag="OPY25_000253"
     tRNA            15863..15938
                     /locus_tag="OPY25_000253"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15896..15898,aa:Val,seq:tac)
     gene            15984..16059
                     /locus_tag="OPY25_000254"
     tRNA            15984..16059
                     /locus_tag="OPY25_000254"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16017..16019,aa:Val,seq:tac)
     gene            16101..16176
                     /locus_tag="OPY25_000255"
     tRNA            16101..16176
                     /locus_tag="OPY25_000255"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16134..16136,aa:Val,seq:tac)
     gene            16181..16256
                     /locus_tag="OPY25_000256"
     tRNA            16181..16256
                     /locus_tag="OPY25_000256"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16214..16216,aa:Lys,seq:ttt)
     gene            complement(16419..17303)
                     /locus_tag="OPY25_000257"
     CDS             complement(16419..17303)
                     /locus_tag="OPY25_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0925976.1"
                     /translation="MERAHRIDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKE
                     LEQQLGTLLFIRHSRSVALTHAGKVLMEESRRLLANANQALARVEQIGRGEAGRIELG
                     VVGTALWGRMRPAMRHFLKANPNVEVLFREKSPGMQMALLERRELDAGIWRMAIEPAV
                     GFTSIRLHESAFMVAVPEDHDLASRDSVPLSALRNEYFVTLPSVHSDWGFLQRVCQQA
                     GFSPMIIREVVEPQTVLAMISMGIGITLMADGYAQMSWPGVVFRPLEERIPADLYIVY
                     DQQQATPALEKLVAALTV"
     gene            complement(17355..17513)
                     /locus_tag="OPY25_000258"
     CDS             complement(17355..17513)
                     /locus_tag="OPY25_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1427 family protein"
                     /protein_id="HCS0925977.1"
                     /translation="MKEIILSSGIGFGIGAFFTLCRIPIPAPNVLPGVLSIVFMYIGY
                     LVVKSIFY"
     gene            complement(17572..18828)
                     /locus_tag="OPY25_000259"
     CDS             complement(17572..18828)
                     /locus_tag="OPY25_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease"
                     /protein_id="HCS0925978.1"
                     /translation="MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVY
                     SSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGALLYATTVTDPQTMFWVMLVN
                     AMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSA
                     QLYIASGASLLLALYALTLPKIPVAEKKANTTLVSKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYAL
                     ALAVIFALFFKYQHHPEKLSTKSLAH"
     gene            complement(18883..19716)
                     /gene="xapA"
                     /locus_tag="OPY25_000260"
     CDS             complement(18883..19716)
                     /gene="xapA"
                     /locus_tag="OPY25_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HCS0925979.1"
                     /translation="MPHALFSHNPEYCIDIIHAHKPAFTPRVAFILGSGLGALADQIE
                     DAVAISYEKLPGFPVSTVHGHAGELVLGHLAGVPVACMKGRGHFYEGRGMAVMTDAIR
                     TLKLLGCEVLFCTNAAGSLRPEVGPGSLVALSDHINTMPGTPMVGPNDDRYGDRFFSL
                     ANAYDADYRAMLQSVAAEKGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCGLKVVAVSAITNLAEGLGDVKLSHAQTLAAAELSRQNFINLICGFLRKL
                     A"
     gene            19972..20733
                     /locus_tag="OPY25_000261"
     CDS             19972..20733
                     /locus_tag="OPY25_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0925980.1"
                     /translation="MKKILTLTLSSLLIIPALTHAEFKGGFADIGLHYLDWTSDTTEK
                     TSKKSHKDDFGYLELEGGANFSWGEMYGFFDWENFYNGRHAKPSSEQRYTFKNTNRIY
                     LGDTGLNLYLHAYGTYGSPHRANFHDDMFLYGLGYNFTGNGYWFKPFFAKRYTDQTYY
                     TGDNGYVLGWVAGYSFSLGSEKFSVTNWNEYEFDRDASYAAGNGGKDGINGAVALWWN
                     ATPHLTAGVQYRYADNKLGESFLQDGIIYSIKYLF"
     gene            complement(20795..21721)
                     /locus_tag="OPY25_000262"
     CDS             complement(20795..21721)
                     /locus_tag="OPY25_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0925981.1"
                     /translation="MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQ
                     TGVRLLDRTTREVVLTEAGQQLATRLERVLDELNSILRDAGRVGTQLTGTVRVAASQT
                     ISAHLIPQCIAQSNSLYPAIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCE
                     AILSEPFLLLCRQDHPLAHQEWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEAD
                     IVQEIGHPATLFPMVEAGIGISVLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNR
                     SLSTAAQALWDVVRTQASELTAARAKDPLYQL"
     gene            21811..22809
                     /locus_tag="OPY25_000263"
     CDS             21811..22809
                     /locus_tag="OPY25_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461360.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HCS0925982.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPAEGGFVPVVEGITTAAIAL
                     LFFMHGAKLSREAIIAGGSHWRLHLWVMCSTFVLFPVLGVLFAWWAPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSLAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNIHGAQGS
                     LEEVGKIMLQLLLPFVLGHLSRPWIGNWVARNKKWIAKTDQTSILLVVYSAFSEAVVN
                     GIWHKVGWGSLLFIVVVSLILLAIVIAINVFVARKCGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVLGMMVLPLMIFHQIQLMVCAGLARRYKRQTEKLQAQQESRAAKA"
     gene            complement(22806..23024)
                     /locus_tag="OPY25_000264"
     CDS             complement(22806..23024)
                     /locus_tag="OPY25_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HCS0925983.1"
                     /translation="MEKEQLLEIANTVMPFGKYQGRRLIDLPEEYLLWFARKDQFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(23026..25041)
                     /gene="ligA"
                     /locus_tag="OPY25_000265"
     CDS             complement(23026..25041)
                     /gene="ligA"
                     /locus_tag="OPY25_000265"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCS0925984.1"
                     /translation="MEPIEQQLTELRTTLRHHEYLYHVMDAPEILDAEYDRLMRELRE
                     LEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKD
                     RPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHVFNFFAE
                     ESNRDVIGQLLAEGVHWPAPVVINAQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVAL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGITVIDEAEMIRLLGA"
     gene            complement(25113..26099)
                     /gene="zipA"
                     /locus_tag="OPY25_000266"
     CDS             complement(25113..26099)
                     /gene="zipA"
                     /locus_tag="OPY25_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HCS0925985.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDDDVEEDEGVGEVRVHRVNHAPGQSQEHDAPRQSPQHQYQPPYASAQPR
                     PAAPPQPQAPMQQPVQQPVQPAPQPQQVQPSAPPVQPPQQQPAPPSQAPQPVAQPAPP
                     PSAQTFQPAEPVVEAEPVVEEAPVVEKPQRKEAVIIMNVAAHHGSELNGEVLLNSIQQ
                     SGFKFGDMNIFHRHLSPDGSGPALFSLANMVNPGTFDPEMTDFTTPGVTIFMQVPSYG
                     DALQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDRIREVMDANA"
     gene            26331..27092
                     /gene="cysZ"
                     /locus_tag="OPY25_000267"
     CDS             26331..27092
                     /gene="cysZ"
                     /locus_tag="OPY25_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HCS0925986.1"
                     /translation="MVSSSTTVPRSGVYYFSQGWKLVTLPGIRRFVILPLLVNIVLMG
                     GAFWWLFTQLDAWIPSLMSHVPDWLQWLSYLLWPIAVISVLLVFGYFFSTLANWIAAP
                     FNGLLAEQLEARLTGATPPDTGILGIMKDVPRIMKREWQKLAWYLPRAIVLLVLYFIP
                     GIGQTIAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKTMRAALRTQKVANMQFGALTSL
                     FTMIPVLNLFIMPVAVCGATAMWVDCWRAKHALWK"
     gene            27465..28436
                     /gene="cysK"
                     /locus_tag="OPY25_000268"
     CDS             27465..28436
                     /gene="cysK"
                     /locus_tag="OPY25_000268"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCS0925987.1"
                     /translation="MSKIYEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASDPQKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFISGVGTGGTLTGVTRYIKGTKGKTDLITVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPGNLDLKLIDKVVGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            28820..29077
                     /gene="ptsH"
                     /locus_tag="OPY25_000269"
     CDS             28820..29077
                     /gene="ptsH"
                     /locus_tag="OPY25_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HCS0925988.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            29126..30853
                     /gene="ptsI"
                     /locus_tag="OPY25_000270"
     CDS             29126..30853
                     /gene="ptsI"
                     /locus_tag="OPY25_000270"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HCS0925989.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADKVDQEVERFL
                     SGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQATALEELDDEYLKERAADVRDIGKRLLRNILGLAIIDLSAIQEEVILVA
                     ADLTPSETAQLNLQKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTAQVKNGDYL
                     ILDAVNNQVYVNPTNDVIEQLRAVQEQVATEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAVRIAMDRKEILRDQVRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            30894..31403
                     /gene="crr"
                     /locus_tag="OPY25_000271"
     CDS             30894..31403
                     /gene="crr"
                     /locus_tag="OPY25_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCS0925990.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIVAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGIELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDPVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(31553..31792)
                     /locus_tag="OPY25_000272"
     CDS             complement(31553..31792)
                     /locus_tag="OPY25_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0925991.1"
                     /translation="MKSYRLVVRQQGRIVGHFETSGLDALEDICVARAMFGITGGYQC
                     ELQVSDSERRILESGPDGMKILMREKCFRPVTSQL"
     gene            complement(31789..32655)
                     /gene="pdxK"
                     /locus_tag="OPY25_000273"
                     /gene_synonym="thiJ"
     CDS             complement(31789..32655)
                     /gene="pdxK"
                     /locus_tag="OPY25_000273"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HCS0925992.1"
                     /translation="MGQESDIQSVLFDDNHRALQTDIVAVQSQVVYGSVGNSIAVPAI
                     KAQGLRVTAVPTVLFSNTPHYKTFYGGIIPAEWFAGYLTALNERDALRELKAITTGYM
                     GSADQIVLLSKWLMAIRASHPEVCILVDPVIGDTDSGMYVQAEIPQAYRTHLLPQAQG
                     LTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVITSAPGESLETITVAVVTAQ
                     VVEVFAHPRVATELKGTGDLFCAELVSGIVQGKKLTTAAKDAAQRVLEVMTWTQQCGC
                     DELILPPAGEAR"
     gene            32738..34030
                     /gene="ptsJ"
                     /locus_tag="OPY25_000274"
     CDS             32738..34030
                     /gene="ptsJ"
                     /locus_tag="OPY25_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PtsJ"
                     /protein_id="HCS0925993.1"
                     /translation="MIDGKTANEIFDSIRQHIIAGTLRAKDSLPPVRELASELKVNRN
                     TVAAAYKRLITAGLAQSLGRNGTVIKGSPSPVALEGGDPHTPLHDLSGGNPDPQRLPD
                     LSRYFARLSRTPHLYGDAPVSPELHAWAARWLRDATPVAGEIDITSGAIDAIERLLCA
                     HLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDSEGMQPEKLEQALNQGARAVILT
                     PRAHNPTGCSLSARRAAALQNILARYPQVLVIIDDHFALLSSSPWQPVIAQTTQHWAV
                     IRSVSKALGPDLRLAIVASDSSTSAKLRLRLNAGSQWVSHLLQDLVYACLTDPEYQHR
                     LAQTRLFYATRQQKLARALQQYGIAISPGDGVNAWLPLDTHSQATAFTLAKSGWLVRE
                     GEAFGVSAPSHGLRITLSTLNDGEINTLAADIHQALNR"
     gene            34045..34764
                     /locus_tag="OPY25_000275"
     CDS             34045..34764
                     /locus_tag="OPY25_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP synthase"
                     /protein_id="HCS0925994.1"
                     /translation="MRVHFVIHESFESAGAYLKWAEDRGYTISWSRVYAGEALPPNAD
                     EFDMLVVFGGPQSPRTTREECPYFDSQAEQHLINQAISARKIVVGICLGSQLIGEALG
                     AKVCQSPEKEIGHYPIVLTEAGQQHPLFNHFGSPLIVGHWHNDMPGLTDQAIILATSE
                     GCPRQIVQYGNFVYGFQCHMEFTVEAVEGLIQHSQQELADAQGKRFIRSVAEMRAWNY
                     QQMNEKLWRFLDELTLAHSQK"
     gene            34823..35200
                     /locus_tag="OPY25_000276"
     CDS             34823..35200
                     /locus_tag="OPY25_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HCS0925995.1"
                     /translation="MKKDFTMKKIVCAVVALLLTLPAWAKLNAHEEARINAMLNVLAQ
                     KKDLTFVRNGDAHNCEEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKI
                     PGKSDENAQPYLHALIAETDKTL"
     gene            complement(35233..36144)
                     /gene="cysM"
                     /locus_tag="OPY25_000277"
     CDS             complement(35233..36144)
                     /gene="cysM"
                     /locus_tag="OPY25_000277"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase CysM"
                     /protein_id="HCS0925996.1"
                     /translation="MNTLEQTIGNTPLVKLQRLGPDNGSEIWVKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDALIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALAMSERGEGKLLDQFNNPDNPYAHYTTTGPEIWR
                     QTSGRITHFVSSMGTTGTITGVSRFLREQEKTVTIVGLQPEEGSSIPGIRRWPTEYMP
                     GIFNASLVDEVLDIHQNDAENTMRELAVREGIFCGVSSGGAVAGALRVARATPGAIVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(36265..37359)
                     /gene="cysA"
                     /locus_tag="OPY25_000278"
     CDS             complement(36265..37359)
                     /gene="cysA"
                     /locus_tag="OPY25_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HCS0925997.1"
                     /translation="MSIEIARIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQSSGHIRFHGTDVSRLHARERKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRDRPTAAAIKTKVTQLLEMVQLAHLADRFPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDRVWREPATRFVLEFMGEVNRLTGTVRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVIEASPKGHYTQLVVQPLGWYHDPLTVVMAGDDVPQRGE
                     RLFVGLQNARLYHGDQRIEPHEALALAESA"
     gene            complement(37349..38224)
                     /gene="cysW"
                     /locus_tag="OPY25_000279"
     CDS             complement(37349..38224)
                     /gene="cysW"
                     /locus_tag="OPY25_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HCS0925998.1"
                     /translation="MAEVTQLKRYDVPRINWGKWFLIGVGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVLIALIAVPMNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQMMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEENHEH"
     gene            complement(38224..39057)
                     /gene="cysT"
                     /locus_tag="OPY25_000280"
     CDS             complement(38224..39057)
                     /gene="cysT"
                     /locus_tag="OPY25_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HCS0925999.1"
                     /translation="MLAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLSQMSW
                     SQYWDVVTNPQVVAAYKVTLLAAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGQFLAQFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAQTLGATRLQSFRKVVLPELSPALIAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            complement(39057..40073)
                     /gene="cysP"
                     /locus_tag="OPY25_000281"
     CDS             complement(39057..40073)
                     /gene="cysP"
                     /locus_tag="OPY25_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HCS0926000.1"
                     /translation="MAVNLLKKRLLTLAAMLLLAGQAQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWSDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADNADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKYVKANGTEKAAKAYLNWLYSPQA
                     QTIITHYYYRVNNPEIMGKQADKFPQTGLFRVEDKFGTWPEVMKTHFASGGELDKLLA
                     AGRK"
     gene            complement(40231..41022)
                     /gene="ucpA"
                     /locus_tag="OPY25_000282"
     CDS             complement(40231..41022)
                     /gene="ucpA"
                     /locus_tag="OPY25_000282"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HCS0926001.1"
                     /translation="MGKLTGKTALITGASQGIGEGIARVFARHGANLILLDISDEIEK
                     LADELGGRGHRCTAVKADVRDFASVQAAVARAKETEGRIDILVNNAGVCRLGNFLDMS
                     EEDRDFHIDINIKGVWNVTKAVLPEMIKRKDGRIVMMSSVTGDMVADPGETAYALSKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPDDPESVLTEMAKAIPL
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPESVSVGV"
     gene            complement(41259..42158)
                     /gene="yfeX"
                     /locus_tag="OPY25_000283"
     CDS             complement(41259..42158)
                     /gene="yfeX"
                     /locus_tag="OPY25_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HCS0926002.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGDLDALRAASRTFADKLATF
                     EVKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFIPYGKGLAPATQYDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIDVKEEVHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSIHDQEMMIGRTKEANEEIDGDARPATSHLSR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDRLLAL"
     gene            complement(42253..42828)
                     /locus_tag="OPY25_000284"
     CDS             complement(42253..42828)
                     /locus_tag="OPY25_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HCS0926003.1"
                     /translation="MKSLRLTLLALPLALTGCSMLSSVNWSAANPWNWFGSSTEVTEQ
                     GVGALTAATPLEEPAIAEALDGDYRLRSGMKTDNGNVVRFFEAMKGDSVAMVINGEQG
                     TVSRIDVLDSDIPTAAGGKIGTPFSDLYSKAFGHCEPVSSDSHTSVECKAEGSQHISY
                     VFSGEWSGPEGLMPPDDVLKNWDVRKIIWRR"
     gene            complement(42890..43339)
                     /locus_tag="OPY25_000285"
     CDS             complement(42890..43339)
                     /locus_tag="OPY25_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HCS0926004.1"
                     /translation="MKSTEFHPADYDVHGCLRLPFLFWCVLLLQARAWVLFVIAGSSR
                     GQGNTLLNFFYPDHDNFWLGLLPGVPAVVAFLLSGRREAVPGVWRWLRGLLILAQLVS
                     LCWLPVMWLGGDPVNGVGLALLLADIVALIWLLTNQRLRACFSLEKE"
     gene            complement(43326..43751)
                     /locus_tag="OPY25_000286"
     CDS             complement(43326..43751)
                     /locus_tag="OPY25_000286"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HCS0926005.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKVNHDVSL
                     FLVAEVSGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQIMVRDDNDVVLGMYERLGYEHSDALSLGKRLIEDEEY"
     gene            43964..44833
                     /gene="amiA"
                     /locus_tag="OPY25_000287"
     CDS             43964..44833
                     /gene="amiA"
                     /locus_tag="OPY25_000287"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HCS0926006.1"
                     /translation="MSTFKLLKTLTSRRQVLKTGLAALTLSGMSHAIAKEETLKTSNG
                     HSKPKTKKTGSKRLVMLDPGHGGIDTGAIGRNGSQEKHVVLAIAKNVRAILRNHGIDA
                     RLTRTGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDRDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPIHKL
                     HSRTTEQAAFVVLKSPSIPSVLVETSFITNPEEERLLGTTAFRQKIATAIANGIISYF
                     HWFDNQKAHTKKR"
     gene            44836..45735
                     /gene="hemF"
                     /locus_tag="OPY25_000288"
     CDS             44836..45735
                     /gene="hemF"
                     /locus_tag="OPY25_000288"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HCS0926007.1"
                     /translation="MKPDAHHVKQFLLRLQDDICQTLSAVDGANFIEDSWRREAGGGG
                     RSRVLRNGGIFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYI
                     PTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGDDVY
                     PRYKKWCDDYFFLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGNGYTEAYLPIVE
                     RRKAMVWGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DWQPEAGSPEAALSEFIQVRDWI"
     gene            45756..46085
                     /locus_tag="OPY25_000289"
     CDS             45756..46085
                     /locus_tag="OPY25_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926008.1"
                     /translation="MQTNTRKVVTSDAKWHPHLGISFIGCLLAITLEIYFEERIFIPH
                     SGGVSFGLIVLLVINMVTIPVVMALIALLCFIIHIPRKSVNCILLCLLACILTIAGLF
                     IAYPVGR"
     gene            46214..47491
                     /locus_tag="OPY25_000290"
     CDS             46214..47491
                     /locus_tag="OPY25_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1963 domain-containing protein"
                     /protein_id="HCS0926009.1"
                     /translation="MDERIPCKNPQCSHFILPATAARTEGYCMPCVQARYRQEQEEYI
                     RKNRKTIDAFSGITNPVEMLKLVHEPREHDPLIEWIPCPIPTDELYKKLSDDESRDMV
                     DYAEELFDSGWQEEAQEIALCLAAFTQANLDNFLRQVINEEELELSSPLPFHRAPPDV
                     RDALLQKVETDDENRDGILCALAWIGDEVVVEHFNRWRQEPPAWSASLHILPHRYAHQ
                     AGWELTENGRRRDLYFTQCTHLVKQAPEQPAVFRAVAEYGENCPHCSLPLINLFEVAP
                     SAVGLSTQGWPGQIRILTCQCCTAYNTVFATVDPQGQPRWYEKNALSTLAVENSSDWI
                     TLPLDVLHPGESRLPLFAAEIFLPTTFSQLGGHPAWVQDTDYPTCPTCAQTMMFLAQL
                     SYEDIEEEEYAEGMLYGFICPSCQTTATSYQQT"
     gene            complement(47691..48743)
                     /gene="eutR"
                     /locus_tag="OPY25_000291"
     CDS             complement(47691..48743)
                     /gene="eutR"
                     /locus_tag="OPY25_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HCS0926010.1"
                     /translation="MKKTRTANLHHLYHEALPEDVKLTPRVEVDNVHQRRTTDVYEHA
                     LTITAWQQIYDQLHLGKFHGEFTEILLDEIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGAQGLGSAEIATRPGGTEFELSTPDDYTILGVVISEDVISRQATFLHNPE
                     RVLHMLRNQLALEVKEQHKAALWGFVQQALATFSESPETLHQPAVRKVLSDNLLLAMG
                     TMLEEAKPIHSAESISHQGYRRLLSRAREYVLENMSEPLTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVRDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMRQWA"
     gene            complement(48791..49285)
                     /gene="eutK"
                     /locus_tag="OPY25_000292"
     CDS             complement(48791..49285)
                     /gene="eutK"
                     /locus_tag="OPY25_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HCS0926011.1"
                     /translation="MINALGLLEVDGMVAAVDAADAMLKAANVRLLSHQVLDPGRLTL
                     VVEGDLAACRAALDAGSAAAQHTGRVISRKEIGRPEEDTQWLIGGFARATTPTEKAPQ
                     VPATPEFAEALLALLASVRQGMTAGEVAAHFGWPLEQARNVLEQLFSDGALRKRSSRY
                     RIKN"
     gene            complement(49298..49957)
                     /gene="eutL"
                     /locus_tag="OPY25_000293"
     CDS             complement(49298..49957)
                     /gene="eutL"
                     /locus_tag="OPY25_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HCS0926012.1"
                     /translation="MPALDLIRPSVTAMRVIASVNDGFARELKLPPHIRSLGLITADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVASIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGIALGDPMAYLVAPPLEATF
                     GIDAAMKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLDIARNPVQR
                     A"
     gene            complement(49967..50863)
                     /gene="eutC"
                     /locus_tag="OPY25_000294"
     CDS             complement(49967..50863)
                     /gene="eutC"
                     /locus_tag="OPY25_000294"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HCS0926013.1"
                     /translation="MDQKQIEEIVRSVMASMGQDVPQPVAPSTQEGAKPQCAAPTVTE
                     SCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADH
                     SRSKDTVLKEVPEEWGKAQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIDALKSQCVM
                     NPDVQVVVSDGLSTDAITANYEEILPPLLAGLKQAGLNVGTPFFVRYGRVKIEDQIGE
                     ILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAA
                     AVIVDLAKRMLEQKASGINMTR"
     gene            complement(50882..52243)
                     /gene="eutB"
                     /locus_tag="OPY25_000295"
     CDS             complement(50882..52243)
                     /gene="eutB"
                     /locus_tag="OPY25_000295"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HCS0926014.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEEDCVTRLIQDDVNETAYNRIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGGKKMPVIKKANTTIGIPGTFSCR
                     LQPNDTRDDVQSIAAQIYEGLSFGAGDAVIGVNPVTDDVENLTRVLDTVYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARYYDPFLVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLETMGIMANGRLTKRAGDPS
                     LFF"
     gene            complement(52255..53658)
                     /gene="eutA"
                     /locus_tag="OPY25_000296"
     CDS             complement(52255..53658)
                     /gene="eutA"
                     /locus_tag="OPY25_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HCS0926015.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSRLELVNRAAVSQVPRYEFIKR
                     DISWQSPVFFTPVDKQGGLKEAELKALILAQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSQSLGDFVVASAGPHLESVIAGYGAGAQSLSEQRMCRVLNIDIGGGTSNY
                     ALFDAGKVSGTACLNVGGRLLETDAQGRVVYAHQPGQMIIDEVFGSGTDARALAAAQL
                     GQVARRMADLIVEVITGALSPLAQSLMQTGLLPADITPEVITLSGGVGECYRNQPADP
                     FCFSDIGPLLATALHEHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEDVQL
                     PLRNLPVAIPQDDADLVNAWRQALLQLDLDPQTDAYVLALPSTLPVRYAALLTVINAL
                     TAFVARYPNPHPLLVVAEQDFGKALGMLLRPQLPQLPLAVIDEVVVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            complement(53655..54881)
                     /gene="eutH"
                     /locus_tag="OPY25_000297"
     CDS             complement(53655..54881)
                     /gene="eutH"
                     /locus_tag="OPY25_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HCS0926016.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLIAMYSGVQINGQPVEFTFALILMNMIPVLIVAVLVALGLKFIPE
                     KMINGFQIFAKFLVALITIGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMNVGKLLNVNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALVDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKDDAAQVKTEAEAQS"
     gene            complement(55000..56187)
                     /gene="eutG"
                     /locus_tag="OPY25_000298"
     CDS             complement(55000..56187)
                     /gene="eutG"
                     /locus_tag="OPY25_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HCS0926017.1"
                     /translation="MQAELQTALFQAFNTLNLQRVKTFSVPPVTLCGLGALGACGQEA
                     QARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQL
                     REAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGQDLAARENMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRD
                     AIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYA
                     AAG"
     gene            complement(56177..57016)
                     /gene="eutJ"
                     /locus_tag="OPY25_000299"
     CDS             complement(56177..57016)
                     /gene="eutJ"
                     /locus_tag="OPY25_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HCS0926018.1"
                     /translation="MAHDEQLWLTPRLQKAAALCNQTPAASDTPLWLGVDLGTCDVVS
                     MVVDGNAQPVAVCLDWADVVRDGIVWDFFGAVTLVRRHLDTLEQQLGCRFTHAATSFP
                     PGTDPRISINVLESAGLEVSHVLDEPTAVADLLALDNAGVVDIGGGTTGIAIVKQGKV
                     TYSADEATGGHHISLTLAGNRRIPLEEAEQYKRSNAQEIWPVVKPVYEKMAEIVARHI
                     EGQGIADLWLAGGSCMQPGVEALFRQRFPELQVHLPQHSLFMTPLAIANSGRAKAEGL
                     YAS"
     gene            complement(57027..58430)
                     /locus_tag="OPY25_000300"
     CDS             complement(57027..58430)
                     /locus_tag="OPY25_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HCS0926019.1"
                     /translation="MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDEVAAAK
                     RAQQGLKSVAMRQLAIHAIREAGEKHARELAELAVSETGMGRVDDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAP
                     HPAAKKVSQRAITLLNQAVVAAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGE
                     AVVDAARKHTNKRLIAAGAGNPPVVVDETADLPRAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAAQAEQLQPVLLKNIDERGKGTVSRDWVGRDAGKIA
                     AAIGLNVPDQTRLLFVETPANHPFAVTEMMMPVLPVVRVANVEDAIALAVQLEGGCHH
                     TAAMHSRNIDNMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            complement(58442..58729)
                     /gene="eutN"
                     /locus_tag="OPY25_000301"
     CDS             complement(58442..58729)
                     /gene="eutN"
                     /locus_tag="OPY25_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HCS0926020.1"
                     /translation="MKLAVVTGQIVCTVRHQGLAHDKLLMVEMIDAQGNPDGQCAVAI
                     DSIGAGTGEWVLLVSGSSARQAHRSELSPVDLCVIGIVDEVVAGGKVVFHK"
     gene            complement(58847..59131)
                     /gene="eutM"
                     /locus_tag="OPY25_000302"
                     /pseudo
     CDS             complement(58847..59131)
                     /gene="eutM"
                     /locus_tag="OPY25_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365323.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
     gene            complement(59172..60188)
                     /gene="pta"
                     /locus_tag="OPY25_000303"
     CDS             complement(59172..60188)
                     /gene="pta"
                     /locus_tag="OPY25_000303"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCS0926021.1"
                     /translation="MIIERARELAVRAPARVVFPDALDERVLKAAHYLQQCGLARPVL
                     VASPFALRQFALSHRMAMDGIQVIDPHSNLSMRQRFAQRWLARAGEKTPPDAVEKLSD
                     PLMFAAAMVSAGEADVCIAGNLSSTANVLRAGLRVIGLQPGCKTLSSIFLMLPQYAGP
                     ALGFADCSVVPQPTAAQLADIAIASADTWRAITGEEPRVAMLSFSSNGSARHPNVANV
                     QQATEFVRERAPQLLVDGELQFDAAFVPEVAAQKAPDSPLQGRANVMIFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPLHDLSRGCSVQEIIELALVAAVPRQADVSRERSLH
                     TLVE"
     gene            complement(60185..60982)
                     /gene="eutT"
                     /locus_tag="OPY25_000304"
     CDS             complement(60185..60982)
                     /gene="eutT"
                     /locus_tag="OPY25_000304"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HCS0926022.1"
                     /translation="MNDFITETWLRANHTLSEGSEIHLPADARLTPSARELLESRRLR
                     IKFLDQQGRLFVDDDEQQPVHGLTSSDTHPQACCELCRQPVVKKPDTLTHLTADKMVA
                     KSDPRLGFRAALDSAIALTVWLQIELAEPWQPWLFDIRSRLGNIMRADAIDEPLAAQS
                     IVGLNEDELHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETLAAQVFIT
                     RSFEVLRPDILQALNRLSSTVYVMMILSVAKHPLTVAQIQQRLGEKP"
     gene            complement(60979..61668)
                     /gene="eutQ"
                     /locus_tag="OPY25_000305"
     CDS             complement(60979..61668)
                     /gene="eutQ"
                     /locus_tag="OPY25_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HCS0926023.1"
                     /translation="MKKLITANDIRAAHARGEQAMSVVLRASIITPEAREVAELLGFT
                     ITECDESVPASTSAQACKSESQRIREAIIAQRPEGQFTESLVAQLMEKVLKEKQSLEL
                     GTMQPSFTSVTGKGGVKVIDGSSVKFGRFDGAEPHCVGLTDLVTEQDGSSMAAGFMQW
                     DNAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTPTSVRFL
                     YVAWPANWQSV"
     gene            complement(61646..62125)
                     /gene="eutP"
                     /locus_tag="OPY25_000306"
     CDS             complement(61646..62125)
                     /gene="eutP"
                     /locus_tag="OPY25_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HCS0926024.1"
                     /translation="MKRIAFVGAVGAGKTTLFNALRGNYSLARKTQAVEFNDHGDIDT
                     PGEYFSHPRWYHALITTLQDVDTLIYVHAANDKESRLPAGLLDVGTRKRHIAVISKTD
                     MPDADVAATRQLLCEIGFREPIFELNGHDPQSVRQLVDYLAALSEQEEEAGEKTYHS"
     gene            complement(62138..62473)
                     /gene="eutS"
                     /locus_tag="OPY25_000307"
     CDS             complement(62138..62473)
                     /gene="eutS"
                     /locus_tag="OPY25_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HCS0926025.1"
                     /translation="MNKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLAMKAADVHIGFLDRFSGALVIYGTVGAVEEALLQTVSGLGRLLN
                     FTLCELTKS"
BASE COUNT        14591 a        17871 c        16155 g        14000 t
ORIGIN      
        1 aggagccatg gggctcctgt ttgcttttct actccgtgct cgcttcaacg ggttttggat
       61 gtgacggcag cacgccatcg gcgcggaaca tcgttttaat ccctctgacg gcctggcgaa
      121 tgcgatcgcg attctctatt aatgcaaagc gtacatgggt gtcgccatag tcaccaaagc
      181 ctatccctgg agaaacgcaa accttcgcct cattcagcag cttcttggca aactcaagcg
      241 atcccatcgc cgcatattgc tccgggattt tcgcccagac gtacattgag gctttcggca
      301 tttcaaccat ccagcccgcc tcatgcagtc ccttcaccag cacatcgcga cgacgcttat
      361 actgctcggc gatatcgcgc acgcactgct gatcgccttc cagagcggcg atagccgcca
      421 cctgaagcgg ggtaaaagta ccataatcgt gataactttt aatgcgcgcc agcgcgctga
      481 ccagggtttt attgcccacc ataaacccaa tacgccagcc cgccatatta tagcttttcg
      541 acagtgtgaa aaattcgacc gccacgtcgc gcgcgccggg cacctgcata atggatggcg
      601 ctttccagcc gtcgtacacg atatcggcat acgccagatc gtgcaccacc agcacatcat
      661 aacgtttagc cagagcgacc actttttcaa aaaattccag ttcgacgcac tgggccgtag
      721 ggttagacgg aaaacccaaa atcatcattt tcggtttcgg ataactttcg cgaatagcgc
      781 gctccagctc gttgaagaaa tccaccccct ctaccaatgg aaccgaacgc acctgcgccc
      841 cggcgataac ggcgccatag atatgaatcg ggtaactggg gttcggcacc agaaccgtat
      901 cgccatgatc cagcgtcgcc agcattaaat gcgccagtcc ctctttggaa ccgatggtca
      961 caatcgcttc ggtttccgga tcgatatcga catcataacg ttcctgatac cagtgagaaa
     1021 tcgcgcggcg taaacgcggt atgccgcggg acgtggaata accgtgcgta tccggacgct
     1081 gcgcgacggt gcaaagtttt tcgacaatgt ggggaggggt tgcgccatca ggattaccca
     1141 tactgaaatc aataatatct tcgccgcgcc gacgcgcagc cattttgagt tcagcggtga
     1201 tgttaaaaac atagggcgga aggcgatcga tacgcgtaaa gcgacgttca gggcgggagt
     1261 cagccataat atcctcagat taacgttagc gcccggaccg tccgagcgac gctgccacga
     1321 tggtggctcc tttagaaaat agcctgaaaa ttttcttcct gtcgagaggc taatgaaaat
     1381 attttttagc gacgaaaaag aggaacaacc gtaaaaattt actttttaag cgtgtcagtt
     1441 atagcaccaa ataaatcaca tcattaacaa attgatatca ttgaatttac ctaacgcggt
     1501 atggccgacg ataatttcct gtcaataaac cttatctcaa ataatcccct tttgattttg
     1561 tggtttttcc tctttaatca aaagccttac taacgataat ggtattcgtt catgtcatat
     1621 tgcggtattt ttcagggata tttccccgaa aataaggatc ctttccggca agctgccgcg
     1681 atgaaagcgt aaataaggca gcgaaccgga tacgtacagt aaaataaatc cctgttttcg
     1741 cctgagtaat caccatgacg tgatgactca acgcgctggt gtttgacttt tcgctcagca
     1801 agagtaaagt gaaataattc agtcagttga agtattcata cacaggaacg gcaatgaaaa
     1861 aaaaccgcgt gaggcacgcg gtttgagact gacaagagaa tgtttcattg cctgatgacg
     1921 ctgcgcttat caggcctaca gatgacacac ttttgtaggc cggataaggc gtttatgccg
     1981 ccgtctgact tatagaatat ggcctaatgt ctggcgcaga tgcgcgccgg agcctaacaa
     2041 gccgggatta tcatggacaa tcagatagac cggaataccg tgtacataat ctttaaagcg
     2101 gcctttatct tcaaagcccc cacggaagcc agacgcttta aagaattcca ggaagcgcgg
     2161 gacaatgccg ccagcgatat aaacgccgcc aaatgtcccc atggttaacg ccagatcgcc
     2221 gccaaatcgc cccatgatga cgcaaaagag cgacaacgcg cggcgacaat cgatacagct
     2281 atccgccagg gcgcgttcgg taatatcttt cgggcgcaga ttttccggca gacggttgtc
     2341 ggacttaaca atcgcccggt aaagattcac cagccccggg ccagacagca cgcgctcggc
     2401 ggaaacgtgg ccaatttcgg cgcgcaatat ttccagaatc atagcttctt cttcgctatt
     2461 aggcgcaaaa tcgacatgcc cgccttcgcc cggaaggcta atccaacgct tatccacatg
     2521 caccagatgc gccacgccca agccggttcc cgcgccgtac accgcaatag gtttgccgtc
     2581 taccggttcg ccgccgccga actgaattaa atgctctttt ttcagcatcg ggatcgccat
     2641 cgacacggcg gtgaaatcgt tgatgatttc cagatgacta aagccgagat tttttttcat
     2701 ttccgcaata gaaaaagccc aggtatggtt agtcatcgcc acccagtcgc cggtaatcgg
     2761 gcaggctatg gcgatacaac catcttccac gctgacgcca tgctcatcga gataaacgcg
     2821 caccacggcc tcaagactgg ggtaatccag gccggaatac gttttggcct gcgagatttc
     2881 tccactggcg atatcacaca gggcaagacg cgcattcgtg ccgcctacat ctcctactaa
     2941 agcatacttt gtcattcttc tactactccg ctaaagtcaa aataagtctt tgtcacactg
     3001 taaattcatg ggggcataac aacaacggcc atcaggctga ctgcctataa atatagatct
     3061 tcatcacaga attactttct tgtttcagca ccaattgcag caatgccgtc gggcaggctg
     3121 tgcaaaatag atatacgacc ccgtgtaagg aagagattat gttccacccg cgtgcccgaa
     3181 cgatgctgct gctgtcgctc cccgcgctga ttattggcgt agcgtcaagc ctagttttaa
     3241 tcgcctcgat gaaagtcgcg tcggtttttc agcaatttct ttggcaacga ctgcccgcca
     3301 gcatcggaat cgcttatgat tcgccgttct ggatagtggg tatgctcacg ctaaccggga
     3361 tcgtggtggg tttgattatc cgttacagtc ccggacacgc tggccccgat ccggccatcg
     3421 aaccgttaat cagtatgccg gtctcgccat ctgcgctgcc cgggctgctt ctcgccttaa
     3481 tcatcggcct tgctggtggg gtaagtttgg ggccagagca tccgataatg acaataaata
     3541 tcgcgctggc ggcggctttc ggctcccgcc tgtttccgcg tatcacggcg ttagactgga
     3601 cgattctggc ctcagcaggc accatcggcg cgctgttcgg cacgcccgtc gccgcggcgc
     3661 tgattttttc gcaaacgctt agcggctcta acgatattcc catgtgggat cgcctgtttg
     3721 cgccgttaat ggcggcagcg gcggggtcac tcaccaccag cctgttcttt catccgcatt
     3781 tttcgttacc catcgcccat tacacgcaga tgcggctggt ggacattgcc agcggagcga
     3841 tcgtcgcggc gatcgccatt gccgccggga tggtcgccgt ctggtgcctt ccgcgtctgc
     3901 acgagttgct gcaccgacta aaaaatccgg tcctgattct cggcattggc ggttttatac
     3961 tgggtattct gggcgtcatt ggcgggccgc ttaccctgtt taaaggcctg gacgaaatgc
     4021 aacaaatggc gtttagccag acgttgggcg cgggggatta ttttacctta gccgtcgtca
     4081 aactcgccgc gctggtcatc gcggcggcga gcggctttcg cggcgggcgc atttttccgg
     4141 ctgtgtttat cggcgcggcg ctggggctca tgctccatgc ccatgttgag gccgtacccg
     4201 cggcgattac cgtctcctgc gcgattcttg gcttagtgct ggtagtgacg cgcgacggct
     4261 ggctcagtct gtttatggcg gcagtcgtcg taccggatac caatctgctg ccgctgctct
     4321 gcattgtgat gctccccgcc tggctattgc tggcgggaaa accgttgctg gccgccaacc
     4381 gtcacgaacc ctaatccggc gcagcggggg ccattatccc ccgttgcggg cttccagcgc
     4441 ccgggtcacg gtacgcagta attccggcag atcggctttt ggcaacatca cttcaataaa
     4501 tgacagacgt tgtgggcgcg ccaaccgttc gaggacctct gccagttgga tagcctgcgt
     4561 cacccgccag cactccgcct gttgcgccgc gtttagcgcc ggtggtatct gcgtccagtt
     4621 ccagctcgcg atgtcgttat accgctgggc cgcgccgtga atggcgcgct ctacggtata
     4681 gccgtcattg ttgagcagca ggatgaccgg cgcctgcccg tcgcgtaaca tcgagcccat
     4741 ctcctgaatc gtgagctgcg ccgcgccatc gccaataatc agaattaccc gccgatcggg
     4801 gcaggcggtt tgcgcgccaa acgcggcggg caaggaatag ccgatagacc cccacagcgg
     4861 ctgaaccaca acttccgcgc cgtcaggaag cgacagcgcg gcagcgccaa aggcggcggt
     4921 cccctggtcg acaaggataa tatcgccggg tttgagacac tgctgtaagg tttgccagaa
     4981 gctttcctgg gtcagttctc ccttatcaat ccgcactggc tgtccggcgg aacgcgtcgg
     5041 cggcggcgca aaagcgcatt caaggcacag ttcgcgcagc gtagacactg cctgcgccat
     5101 cgggaggttg aaccaggttt cgccgatgcg cgacgcgtaa ggctgaatct ccagcgtgcg
     5161 ttccgccggc aattgttggg taaatccggc cgtaagggta tcgacaaaac gggtgccgac
     5221 gcagataacc ctatcggcgt cctctatggc ctgacgtact tctttgctgc tggcgcctgc
     5281 actataggtg ccaacgaagt tcgggtgctg ttcatcaaaa agccccttcc ccatcagtag
     5341 tgtcgcatga gcgatgggcg tttccgccat ccagcgctgc aacagtggtc gtaaaccaaa
     5401 acgcccggca agaaagtcgg ccaatagcgc aatgcgccga ctgttcatca ggcactgacg
     5461 ggcgtggtaa cgaaaagccg tctccacgcc gctttgcgct tcatgcacgg gcaacgccag
     5521 cgcctccgta ggcgggatag ccgttttttt cgccacgtcg gcgggcagca tgatgtatcc
     5581 tggcctgcgt gcggcaagca tttcacccaa tacgcggtca atctcgaaac aggcgttctg
     5641 ttcatccaat attgcgctgg cagcggatat cgcctgactc atgcgataaa aatgacgaaa
     5701 atcgccgtca ccgagggtat ggtgcatcaa ttcgccacgc tgctgcgcag cgctacaggg
     5761 cgcgccgacg atatgcaaga ccgggacata ttccgcgtaa ctgcccgcga taccgttaat
     5821 agcgctaagt tctcccacgc caaaggtggt gagtagcgct ccagcgcccg acatgcgcgc
     5881 ataaccgtcc gcggtataag cggcgttcag ctcattggcg catcccaccc aacgcaaggt
     5941 cgggtggtca atcacatggt caagaaactg caagttataa tcgcccggta cgccaaaaag
     6001 atggccaatg ccgcatcctg ccagtctgtc cagcaaatag tcggccacgg tataggggtt
     6061 ttgcatgaca gctttccttc tgacgttgac attatgttga gtattaagga atgccgatgg
     6121 ctgtccagca cggcggggat gaaagcctgg aaaacaatgt ttacagcggc aaacagtaaa
     6181 agccggatac cgcctggcga gtgtaaccgt atacactatt tattcacgcc acagggggaa
     6241 aggtcatgat ttatcagccc gatgagaatc gttatcacac aatggagtat cgtcgctgcg
     6301 ggcgcagcgg cgtcaaactt cccgctattt cgctggggtt atggcacaac ttcggcgata
     6361 cgacacgggt agaaaatagc cgggcgctgc tgcaacgcgc gttcgatctg ggcattaccc
     6421 actttgatct cgccaataat tatgggccgc cgccgggctc cgcagaatgc aattttggcc
     6481 gcattctgca ggaagatttt ttaccgtggc gcgatgagtt agtcatctcc accaaagcgg
     6541 gctacaccat gtgggatggc ccttatggcg actggggttc acggaaatac cttatcgcca
     6601 gcctcgatca aagcctgaaa cgtatggggc tggagtatgt cgatatcttt tatcaccatc
     6661 gtcccgatcc cgaaacgccg cttaaagaga cgatgaaagc gttagatcac cttgtgcgcc
     6721 acggcaaagc gttgtacgtg gggatctcta actatcctgc cgatctggcc agacaagcta
     6781 tcgatattct ggaggatctc ggcacgcctt gcctgattca tcagcctaaa tattcgcttt
     6841 ttgagcgttg ggtagaggac gggctgctga cgctgttgca ggaaaaaggc gtcggcagta
     6901 ttgccttctc gccgctggcg ggcgggcagc tcactgaccg ttatctgaat ggcattccgg
     6961 aagattcccg cgcggcgagc ggaagccgtt tccttaaacc agaacagatt accgccgaca
     7021 aactggaaaa agttcgccgg ttgaatgaac tggctgcacg acggggccaa aaattgtctc
     7081 agatggcgct cgcctgggtg ctgcgtaacg ataacgttac ctcggtactg attggcgcca
     7141 gcaaaccgtc gcaaatcgaa gacgccgtag gaatgctggc caatcgccgt ttttcggcgg
     7201 cggaatgtgc agaaattgac gctattctgg agggccggtt ttagcaaaaa atgctctcct
     7261 tcatgattta agagttaagg cgatgaaaca aatctttact gctttgtaat attgcattaa
     7321 caggccggcg acggctcgat cgtgaaggag agaaagtatg ttcaggtcac tgattctggc
     7381 ggcagccttg ctggctttta caccgcttgc cgcgaatgcg ggcgaaatca ccctgttgcc
     7441 ctcaataaaa ttacagattg gcgatcgcga tgattacggt aactactggg acggtggtcg
     7501 ctggcgcgac cgggattact ggcacaacca ttatgaatgg cgtaaaaatc gctggtggcg
     7561 ccatgacaac ggctatcatc gcggctggga taagcgtaaa gcgtatgaac gcggttatcg
     7621 ggaaggctgg cgcgatcgcg acgatcatcg cgggcgaggc cggggtcaca aacatcatca
     7681 ctaagcctcc tgctgaataa cagcccgatg acgcccacgc atcgggcctg ctatctttct
     7741 gtctttatga caaccccatc accgttccaa ccagcaacca gatattcagg gcgacgacca
     7801 gcacgacaat tatccagcca atctgtttta cccgccgcgt gttcaccagc tcgcccatta
     7861 gcgtagcgtt actggtgaaa atcaggagcg gcaccagcgc cagcgcaata ccaaaactca
     7921 gcagcacctg gctcatcacc agaattcggg tagggtccag ccccatcaaa atcacaataa
     7981 atgagggcag catggtaatg gtgcgccgta cccacagcgg aatgtgaaaa cggacaaacc
     8041 cttgcatcac cacctgcccc gccagagtcc ctaccacggt ggaggaaagc cctgccgcaa
     8101 ccagactaag accaaacact gttgccgccg catggcttag taacggttcc agcgtcaggt
     8161 atgcctgatc gaggtcggcg atgccagtat ggccgctaaa atgaaacgcc gccgcggcgg
     8221 tcgccatcat tgccagattg acaaaaccgg caatcgtcat ggcaatagcg acatcccatt
     8281 tcgttgctga gtaccgttgt tgccgcgttc cgccgtgcag atgctgcgtt aatgacgagt
     8341 gcagataaat cacgtgcggc ataatcgtcg cgccaagcac gccggcggct aagaatacgg
     8401 cttccgggtt cggtagcgcc gggataacca ttcctttgcc gagctgcgcc atatcaggct
     8461 gagagaaaaa cagctccaca atgtaagcgg cggcgacaaa aagcagtaaa ccgccgatga
     8521 ctttttcaag cggtttttga ccgcggcgct gtaacattaa aatcagaaac gtcgcgatac
     8581 cggtcaatac cgcgccctgt agtaaagaga cgcccaggat cagcttaaaa cctattgccg
     8641 cgccgataaa ttcagctaaa tcggtggcca tcgcgatgat ttccgcctgt acccagtaaa
     8701 accagactac cggacgcgga taatggtcgc gaatttgctc cgccaggttc ttgccggtgg
     8761 cgatcccgag ttttgccgag aggatttgaa tcagcatcgc catcaggttc gcccagacca
     8821 ccacccagag tagctggtag ccaaagctgg cgccggcctg aatattggtc gcgaagttac
     8881 cgggatcgat ataaccaatc gcggcaatga acgcaggtcc cattaatgcg agccttagct
     8941 tgcgcgccgc ccgtccgctg ctattctcta cgcgattgtc agtcatcttt tgcctcaaaa
     9001 acatagcctt tgctatgttt catgctatgt tcattgataa tgattatcaa gtgcatttca
     9061 atgggtacgg gtgattactt tgatagtgtg aaacgataga ccgatacgat ggcgacctgt
     9121 atcagaacag tttggcttaa cattacaaga ttagcacact gatataactt ttcattttca
     9181 tattcagtac agtaaaagtg tattacagat cactaatttt gaatctcgtc acaggtcctt
     9241 attatagtgt gtgttggatc tcgttttctt tacagctgtt gcatagaatg tgcacgaaaa
     9301 ttaaacctgc ctcatatttg gagcaaatat ggaccgcgtc cttcattttg tcctggcgct
     9361 tgccgttgtt gcggtactcg cactgctggt tagcagcgac cgtaaaaaaa ttcgcattcg
     9421 ttacgtcatt cagttacttg ttatcgaagt gttactggcc tggttcttcc tgaactcgga
     9481 tgttggcctt ggcttcgtaa aaggtttctc cgagatgttt gaaaaactgc tcggatttgc
     9541 caacgaaggg acaaacttcg tctttggcag tatgaacgat caaggtttgg cgttcttctt
     9601 cctgaaagta ttgtgcccga tcgtctttat ttccgcgttg atcggtattc tccagcatat
     9661 ccgtgttctg ccagtggtca tccgcgctat tggtttcctg ctatccaaag taaacggtat
     9721 gggcaaactg gaatctttta acgccgtcag ctcgctgatc ctcggccagt ctgagaactt
     9781 tatcgcttat aaagatattc tcggtaaaat gtcccgtaac cgcatgtaca ccatggctgc
     9841 aacggcgatg tctaccgttt ccatgtctat cgtgggcgcg tatatgacca tgctggaccc
     9901 taaatatgtg gtcgcagcgc tggttctgaa catgttcagc acctttatcg ttctgtcgct
     9961 gatcaacccc tataccgttg atgccagcga agaaaatatt cagatgtcga acctgcatga
    10021 aggccaaagt ttcttcgaaa tgttgggcga gtacattctg gcaggtttta aagtggcgat
    10081 tatcatcgcg gcgatgctga tcggcttcat cgcgctgatc gcggcgctga acgcgctgtt
    10141 cgcaacggtt accggttggt tcggctacag catctccttc cagggcattc tgggttacat
    10201 cttctacccg gtcgcatggg taatgggcgt accgtccagt gaagcgctgc aggtaggaag
    10261 tatcatggcg accaaactgg tttccaacga attcgtggcg atgatggatc tgcagaaaat
    10321 cgcctctacc ctctctccac gcgctgaagg cattatctcc gtcttcctgg tgtccttcgc
    10381 gaacttctct tccatcggta ttattgcggg cgcgattaaa ggcctgaacg aagagcaagg
    10441 caacgtggtt tcccgttttg gtctgaaact ggtttacggt tctacgctgg tgagcgtact
    10501 gtccgcctct atcgcggcgc tggtactgta agtctgcgtt taatgtagaa accggggagc
    10561 tatccccggt ttttttatgc cgcttatttg cctaacgggc gcgggcggcc aatcagatat
    10621 ccctgcaaac tatgtacgcc aagctgcaat agcagatcgc gctgcgcagg cgtttcaaca
    10681 aactcagcca cgacgctcaa cgatttcgct ttcgctaaat cagtgatgga tttcacgatc
    10741 atcgcatcca gggagtccgt cagaatatct tttacgaaac aaccgtcgat tttaatgatg
    10801 tccgccttga ggcgttttag ccgttcatag tttgcataac cggtgccgaa atcatcaatg
    10861 gcgattttta ggccaaactt acgcagctgg ttgatattgt gcatactgat ttcggaatga
    10921 gagaaggcct gttcttcagt aatttcgatg atgaccgaag caggcgggac gccatagcgt
    10981 ttaaaaagct gcataatgcg cgacgccgtc tctttttgca gcagcgtcag cggcatcaaa
    11041 ttaaccgaaa aacgcgcccc ctgctccgcc gaaggatgcg cggacaacca ttgcaggagc
    11101 gcttccatca cctgcatatc aaaccgtacg ctcaggttaa actgggcgat aagcggaatg
    11161 aactgattcg gcatcatgat accgtcgtcg caccgaagcc gcgtcagaat ctcgtcatac
    11221 ccttttccct gcgcgtcgcg aatgggttgc gcatacaaaa ccagcgcgcc gcgctccagc
    11281 gcctgacgga ttttctgcaa ccgcagcacc cgttccgtcg tctgcccgga agcggcttca
    11341 atactctggg tcagtgcaag cacccgacgg tgcgagcagg attgctccgc cagccagctt
    11401 aattgcccca acagcggttg caaggtttcc tggcgaccat cgaatgttcc ccacgatgcg
    11461 ccgtattcca tgtccagacc ggtattgttc cagtaaattt tgcggttatt aagcacattg
    11521 agcatatatt gcaggcgggc ttccgtctcc ggtcccgtca ataccagcaa taattcactg
    11581 cccggcagat ggaaaatttt ctccttttcc agcagcagcg gctgcaacac gcgaaacacc
    11641 tcgcgttcgc aatgcacgcg catctgcata ccgtaatgac ggctcagaaa ttccaggttt
    11701 tccatgcgta gataacacac gctttgcccg gcatcctgta aaagaaactg ccccagcgcg
    11761 cgcaagttag gcagttgcgt caacggatcg gtcaatgcct gcgagtgcca ctgtcgattc
    11821 aaccattcgc tacgctgatt aatccgcgcc atgtacaaca aacaaatact aaaagaaatg
    11881 agaactgaaa ggataaatgc cagcgaatat tctgaaccca cgccctgcag aaaattgcgg
    11941 ttatagctaa gcaggaatag cgcagtgaga gcccaactaa aattcaacag cggatagctg
    12001 attttcccca cgccgatggt aaatccaatg aacagaactg gcaccagata gccagcaata
    12061 tactttgtct cgaaaggcgt acacagcacc gctaatagcg tcgccagagt ggcaaaccag
    12121 agaagcgtaa acaggcgttt ttctttggcg agataaggag cgacatccct ccgccagaaa
    12181 atacgcatat agtgcgggct gactatcatt cgcagcggat aatagaaaaa gagggtaaaa
    12241 ataagcgcgg cagaaatcag actcaataaa tcgacaatcg agaaaatagc ggtgccggtg
    12301 ccaaagaagg tagagatggt caccgggaaa gccaggtagt gccccgccag atgcatactg
    12361 atttttatac caaacggcgt cattaaccct aaccagaaaa cgcgtagcca gatgccttgg
    12421 ttgggtattc cgtagcgcca gcgcgcgccc agctgccagc gtacgatagc gcaaaccagc
    12481 aacacgggaa acgtctggca aaatagcagc accatcgcct gtggcagagg taaatgaaaa
    12541 ttccattcat tagtcaacat cattccgcct accatcggcg cgacgccacg gcggccaaat
    12601 aaaaacagca cggaaaacat gacgcagagc ggtagccagg ccagaaagat atagctggaa
    12661 tcaattgtgg cgcggggaga aatgagacga gatagcagaa tagccggaac ggtcaggcag
    12721 aaggccagta agaatatttt tatatttttt aatacgttac acttatccgg cattgcttta
    12781 atgctcacat cattatataa ggcgcatgaa taataagtat attcgcatta tgaagcaatc
    12841 taacaaaagc tcatattgac cgcaaaagca gcggcaaacg aacgcacctg aagagcagat
    12901 cagacgccat gaattttgtg acaaaaagca aaaacccccg cttttcagcg agggtttgaa
    12961 cgttggtgga gctaagcggg atcgaaccgc tgacctcttg catgccatgc aagcgctctc
    13021 ccagctgagc tatagcccca tagtgctttt acgtatacgc caaatttatc gggagtaaat
    13081 ttggtggagc taagcgggat cgaaccgctg acctcttgca tgccatgcaa gcgctctccc
    13141 agctgagcta tagccccact acgtaaagct tgtcgagttg acgggcggca tcatatgaat
    13201 tccctcggca tgtgtcaacg gcaaaatgaa cttgccgaat tcaatcgctg aaaaagcatt
    13261 caaataaagg acattgcggc acaactcgca ttcagtagtt aaacacgtca cggtttcgac
    13321 taaaatggtg ctataaaatg aaccactaat taaccccacg actattcagg gaatcgttat
    13381 gttcaaggaa cggatgacgc cagaagaact cgctaatctc accggttaca gccgacaaac
    13441 catcaataaa tgggtacgga aagaaggctg ggcaacatcg cccaaacctg gcgtccaggg
    13501 cggtaaagcc cgtctggttc atgtaaacga acaggttcgt gaatatatcc gcagcgctga
    13561 acgttcagtt gaccatcacg cagacacatt cacgcctgcc agcaacgcat cgcttgaagc
    13621 gctgctcatg acgctcgcca aagagatgac ctcatccgag cagaaacagt ttacctctct
    13681 cctcgtgcgt gaagggatta ccggtttgtt acaacgctta gggatacgcg atagcaaata
    13741 atatgaaaag attacgcagt aaaatgacca ctgaagagct ggctgaatgc ctcggcgtgg
    13801 ccagacaaac cgtcaatcgc tggatcagag aacaacactg gaaaaccgaa aaatttcccg
    13861 gcgtcaaagg cggacgcgca agactcatcc atattgatgc cagcgtgcgg gagtttattc
    13921 tcaatattcc ggcttttcgc aaactgcctg cgttttatca ggcggaagag gctttcgcag
    13981 aatatgcgaa cgcgacgcac agtcacgctt atcgacaaat tattgatgcc gttgaaaata
    14041 tgtctgctca ggaacaggaa aaactggcgc tgtttttatc gcgggaaggt attcgcggat
    14101 ttctgacgcg tttaggtatc aatgaggcgg actaacaaat aataaacggc aggcgtctgc
    14161 cctgccgttt attctgtttc agctggcgtt actgctgact ttcacgctcg gcgataaagc
    14221 ccagcgcttt gttgatacgc tcaatgctgc gggttttacc aatcgcatgt acggtgacat
    14281 ccagcgcagg cgactgcccg gcaccggtca cagccacacg cagcggcatc cctactttac
    14341 ccatccccac ttccagctca tccgccgtgg cctgaatcgc gtggtggacg ttttctgctg
    14401 accagtccgt aatcgccgac agcttgtcgc gcaccacttc cagcggctga cgcgccaccg
    14461 ggcggaggtg ttttttcgcc gcatcggcgt caaactcgct gaagtcttca tagaagtagc
    14521 ggcagctctg cgccatctct ttcagagtct tgcagcgttc gcccagcaac ttcaccagct
    14581 cagcaagctg cgggccgtta cgggtgtcga tattttcctg ctcgatatgc cactgcaaat
    14641 gcgtcgccac atattccggc gccagcgtat tgatatagtg gtggttcagc cacagcagtt
    14701 tatcggtgtt gaacgcgctc gcagacttgc tcaccgcacc gagggagaac agcttgatca
    14761 tctcttcgcg ggtgaagatt tcctgatcgc cgctggacca gcccagacgc accagatagt
    14821 tcagcaacgc ttccggcaga taaccgtcat cgcgatactg catcacgctc accgcaccgt
    14881 gacgtttaga cagcttttta ccgtcgtcgc cgttaatcat cgacacatgc gcgtacatcg
    14941 gcaccggcgc gtttaacgct ttcagaatgt taatctggcg cggagtattg ttgatatggt
    15001 cttcgccacg aatcacatgg gtaatttcca tatcccagtc gtccaccacc acacagaagt
    15061 tgtaggttgg ggaaccgtcg gtacgacgaa tgatcagatc gtccagttcc tgattgctga
    15121 attcgatcgg gccacggatc tgatcatcaa aaataacaga accgtcctgc gggttggcaa
    15181 agcgcaccac gcatggctca tcgtcggcat gatgttcgtg gctgtgacgg caacgcccgt
    15241 cataacgcgg cttctcgcct ttcgccatct gatcttcacg cagttgctcc agacgctctt
    15301 tagagcagta gcatttatag gctgttcccg cctccagcat ctcgtcaatc accgcgttat
    15361 agcgatcaaa acgtttggtc tggaaatatg ggccttcgtc ccattccagg ttcagccagt
    15421 tcataccatc catgatggct tcaatggctt ccggcgtgga acgctcaaga tcggtgtctt
    15481 caatacgcag cacgaattca ccgccgtggt gacgtgcgaa aagccaggaa taaagagcag
    15541 tacgcgcgcc gccgacgtgc agataacctg tcgggctagg cgcgaagcga gttttgattt
    15601 tcatgaaatg gccttacgtt tataaagatg ccgacaaccg gcaaatcctg gaaagatgaa
    15661 tagccttgta ttctatcact gtggcttgat tcctcaatgt tgatccggtc agaacgctgc
    15721 gctttgctat ttccgtatag aaatcatgca gtgcggggta attcacgatc gttttgttta
    15781 attttacgac gaacaaacaa aaactttaga aaatgcgttg actcattttc aactctccct
    15841 ataatgcgac tccacacagc gggggtgatt agctcagctg ggagagcacc tcccttacaa
    15901 ggagggggtc ggcggttcga tcccgtcatc acccaccaac tactttatgt agtctccgcc
    15961 gtgtagataa gaaattgaga agtgggtgat tagctcagct gggagagcac ctcccttaca
    16021 aggagggggt cggcggttcg atcccgtcat cacccaccac tttctcgcca gctaaatttc
    16081 ttattgtgaa gtaccgaagt gggtgattag ctcagctggg agagcacctc ccttacaagg
    16141 agggggtcgg cggttcgatc ccgtcatcac ccaccacttc gggtcgttag ctcagttggt
    16201 agagcagttg acttttaatc aattggtcgc aggttcgaat cctgcacgac ccaccaatgt
    16261 aaaaaagcgc cctaaaggcg cttttttgct atctgcgatt tataagattc gaacctgccg
    16321 caggttcggg tcttgcctga tgcgctgcgc ttatcaggcc tacagacgac accgccgcgt
    16381 aggccggata agacgttagt cgccatccgg cacagacatc ataccgtcaa cgccgccacc
    16441 agtttctcca gtgctggcgt tgcctgctgc tggtcataca caatatacaa atccgccgga
    16501 atacgttcct ctaacggacg gaacaccaca cccggccagc tcatttgcgc atagccatca
    16561 gccatcaacg taatcccgat ccccatactg atcatcgcca acaccgtttg cggctcaacc
    16621 acttcccgaa taatcattgg cgagaaaccc gcctgttggc atacacgttg taaaaatccc
    16681 caatcagaat gtacggaagg caacgtaaca aaatattcat tgcgcaacgc cgacagcggc
    16741 acagaatctc tggatgccag atcgtgatct tccggaactg caaccatgaa tgcagattca
    16801 tgcaaacgta tgctggtaaa accgactgct ggttcgatag ccatacgcca gatccctgca
    16861 tcaagttccc gacgctctaa caacgccatt tgcatacctg gagacttttc gcgaaaaagt
    16921 acttcaacat tgggatttgc tttcaaaaag tgacgcatcg caggacgcat tcttccccac
    16981 agcgccgtac caaccacacc cagttcaatg cgccccgctt caccgcgacc aatctgctcc
    17041 actcgcgcca gcgcctgatt tgcattggct aacaagcgac gtgactcctc cattaaaact
    17101 ttcccggcat gggttaatgc aacgctgcgg gaatgacgaa taaacagcaa tgtacccagt
    17161 tgctgttcaa gttctttgat atggatactc aagggaggtt gtgacatatt taaccgggca
    17221 gcagcccggc caaaatgcaa ttcttctgca acagcgagga aataacgtaa tagctttaga
    17281 tcaatacgat gggctcgttc catcactatc gcactccagg aataagggat aacgtctgga
    17341 atttaccata ttacctagta aaaaatagat ttaacgacaa gatacccaat atacataaat
    17401 acaatagata aaaccccggg taaaacattt ggtgcaggaa taggtatacg gcataaagta
    17461 aaaaatgcgc caataccaaa tccaataccg gaggagagaa taatttcttt catactgtgt
    17521 ccttgttcat aaaaatggac tggcgaacat cctctcgcca gtcaaataaa attaatgtgc
    17581 taatgatttg gtcgacagtt tttctggatg gtgctgatat ttaaagaaca atgcaaaaat
    17641 aacggccaat gccagagcgt aggcggcaaa aaccagccag atggtttgcc aatcttttac
    17701 gccatcaata gaaaaataat ccacggccat accgcttaaa agagacccaa tccacgcccc
    17761 cacgccgtta accatggtca taaacagccc ctgcgcgctg gcgcgaatac ttgagtccac
    17821 ctcctgctct acaaatactg accctgagat gttgaagaaa tcaaatgcgc agccataaac
    17881 aatcatcgac agcagcaata gcacaaagcc aaacggggat ggatcgccaa aggcaaagaa
    17941 gccgaaacgc agcgtccacg ccagcatgct catcagcatt accgttttaa taccaaagcg
    18001 tttaaggaag aacggaatgg tgaggataaa gcccacttcc gccatctgcg aaactgaaag
    18061 caagatagag ggatacttca ccacaaaact atcggcaaac tcaggattac gggcaaaatc
    18121 atgcaggaac ggattaccga agacattggt aatttgcagc accgccccca acatcatcgc
    18181 aaacaaaaag aagattgcca tgcgtggatt tttaaacaga acaaaagcat ccagtccgag
    18241 cttactgaca agcgtggtgt tcgccttctt ctcggctacc ggaattttcg gtaacgtcag
    18301 cgcatacagg gccagcaata acgatgcgcc agaagcgatg tataattgcg cactgctcag
    18361 ttccagcccc atcaggctca ccgtccacat cgcaacaata aaacctattg tgccgaaaac
    18421 gcgcacgggc ggaaatgacg ttaccggatc ctgacctgct ttcgccagac aggagtacga
    18481 aacgctattg gataatgcaa tcgttggcat atacgccatc gcattaacca acatcaccca
    18541 gaacatcgtc tggggatcgg taacggtggt ggcgtacaat aacgcccccg cgcaaaccag
    18601 atggcaaagc atataggctc gctcagcgcg cagccattta tcagcaatga tccccataat
    18661 gcccggcatg ataatcgctg ccagtccttt tgagctgtag accataccga cattcgcgcc
    18721 ggtaaaatcc agagtgttga tcatgtaaga gcccagggta accagccagc tcccccagat
    18781 aaaatattgc aagaacgaca tgacttttaa gcgggacgta atacccattt tttattcctt
    18841 gccgtgagat aaagccccaa tacggggccg tagtcattgt gtttaggcca gcttacgtaa
    18901 aaagccgcaa atcagattga taaagttctg ccgggaaagt tcagccgccg ccagcgtttg
    18961 cgcatgggag agttttacat cgcccagccc ttccgccaga ttggtgatcg ctgagacggc
    19021 aacaactttg aggccacaat gacgtgcgct aatcacctca gggacaacgg acattccgac
    19081 cacatcgccg ccaataatct gcatcatgcg gatttctgcc gccgtttcga agttcggacc
    19141 cggataagaa acaaatacgc cttcagtgag ggggaatccc ttctctgccg caacggactg
    19201 aagcatggcg cgataatctg cgtcataagc attagccagc gagaagaagc gatcgccata
    19261 acgatcatcg tttggcccca ccatcggcgt accgggcatc gtattaatgt gatcgctaag
    19321 cgcaaccagg ctacccggcc ccacttccgg acgcagagat cctgccgcat tggtgcagaa
    19381 caacacttca cagcccagta atttcaacgt gcgaatggca tcggtcatca ccgccattcc
    19441 acgcccttca taaaaatgtc cgcggccttt catacaggcc accggaacac ccgccagatg
    19501 gccgagcacc agttcaccag catggccgtg tacggtgctg acgggaaatc ccggcaattt
    19561 ctcgtaagaa atggctaccg catcttcgat ttgatccgcc agagcaccca acccggagcc
    19621 taaaataaac gcgactcgcg gggtaaatgc cggtttatgt gcatgaataa tatcaataca
    19681 atactcagga ttatgagaaa aaagagcgtg aggcataagt ttccttgttc tatcggattt
    19741 aatttgactc ctttttataa cgaccatcgc cccttgctga ccaatacact tttcacgtgt
    19801 catcaatagc catttaatat cgatagattt agatcgcttc tgtattaata cagagggaaa
    19861 acagtattgg tttttgcttg cacttcatat taacaatatg ccgctttcat atttataaat
    19921 tgcctctttt taattaaccc attaataatt atcggcatag ggaaatatgc tatgaaaaaa
    19981 attcttactc tgacgctttc ttctttactc attattcccg cactcaccca tgcggaattt
    20041 aaaggcgggt tcgccgatat cggcctccat tacctcgact ggacatcaga caccacggaa
    20101 aaaaccagta aaaaatccca taaagatgat tttgggtacc tggaactgga aggcggagcg
    20161 aattttagct ggggagaaat gtacgggttc ttcgactggg aaaattttta caatggccgc
    20221 cacgctaaac caagcagcga acagcgttac acctttaaaa ataccaaccg tatttatctg
    20281 ggcgatacag gattaaacct ctatctccat gcctacggga cgtacggttc acctcatcgc
    20341 gctaatttcc atgatgacat gtttctctat ggtttaggct ataacttcac aggtaacggt
    20401 tactggttta aacccttctt tgccaaacgt tataccgatc agacctacta cacaggcgat
    20461 aatggttatg tattaggttg ggtggccggc tatagcttct cgttgggtag tgagaaattc
    20521 agcgtaacga actggaatga gtatgagttt gaccgcgatg cgtcctacgc tgcgggcaat
    20581 ggcgggaaag atggcattaa tggcgcagta gcgctgtggt ggaatgcgac tcctcacctg
    20641 accgcaggag tacaatatcg ttacgctgat aataagttag gagaatcctt cctgcaggat
    20701 ggcattattt attccatcaa atacctgttt taacacactg ccctgtcaaa aatggcaggg
    20761 caagaccgca cctcacacac ggacagatag atatttatag ctgatacagc ggatctttcg
    20821 ccctcgcggc ggttaattcg ctggcctgag tacgcaccac gtcccacaac gcctgcgccg
    20881 ccgtggagag cgatcggttt tttcgccgcg ccagcatgag ctgcctttca actacgggcg
    20941 tcagccgttt aacctgtaag tggctgccct gcgggagcgg taacgccagc gcgggcagca
    21001 cgctgatgcc gattcccgct tccaccattg gaaacagcgt ggccgggtga ccaatctcct
    21061 gcacgatatc cgcctcaata gcaaaatggg ccagcgccgc atcaatcagc ggtcgactgc
    21121 cggaagcata atcctgtaag accagcgagg cctgtttaag atcctgccag ctcacccatt
    21181 cctgatgcgc cagcggatga tcctggcgac acaacagtaa aaaaggctct gataagatgg
    21241 cttcacactg taaatccacc gctgcgccgg gatcgataac gatgccaaaa tccacttcac
    21301 cctggcggat gctctccagc acccactgct gcggacgatc gtgcaataca aaatcaatag
    21361 cgggataaag tgaattactt tgggcaatgc attgcggaat aagatgcgca gaaatggttt
    21421 ggctcgcggc aacgcgcacg gtgccggtta attgtgtccc tactctgcct gcatcgcgca
    21481 gtatgctgtt cagttcatca agcacccgct ccagacgcgt cgccagctgt tgccccgcct
    21541 cggtcagcac cacctcacgc gtggtgcgat ccaacagtct gacgccggtt tgccgctcca
    21601 gctcttttac gctatgactg accgcagact ggctcagtcc aatcctgtcc cctgcccgac
    21661 taaaactttt ggcctgggcg acggtaataa aaatccgcag ttgacgcagt gaatagttca
    21721 tcgactagat tcatatatag atgcaataaa tcaattttat ttctcaaagc gaaaaacgca
    21781 aaatagctgc accgactttc aggagttttt atgaaacttt ttcgtatcct tgaccctttc
    21841 acgctgacac ttatcaccgt ggtactactg gcctcttttt tcccggcgga aggtggcttt
    21901 gtgcctgtcg ttgaaggcat tacgacagcg gctatcgctc tgctgttttt tatgcatggc
    21961 gcgaagcttt cgcgtgaagc gatcatcgct ggcggcagcc actggcggtt gcatctgtgg
    22021 gtcatgtgca gcacttttgt gctctttcct gtcctcggcg tgctgtttgc ctggtgggcg
    22081 cctgtcaatg tcgaccctat gctctacagc ggctttctgt atctgtgtat tttgcccgcc
    22141 accgtgcagt cggcgattgc atttacttca ctcgcgggcg gcaacgtcgc ggccgcggtg
    22201 tgctcagcgt ctgcgtccag cctgctgggc attttcctgt cgccgctgct ggtcggtctg
    22261 gtaatgaata ttcatggcgc gcagggcagt ctggaagagg tgggcaaaat tatgctgcaa
    22321 ctgctgctgc cttttgtgct gggacacctg tctcgcccgt ggatcggcaa ttgggtcgcg
    22381 cgcaacaaaa agtggatcgc gaaaacggat cagacctcta ttctgttggt ggtctactcg
    22441 gcgttcagcg aagcggtggt caacggcatc tggcacaaag tcggctgggg atcgctgctg
    22501 tttatcgtcg tggtcagcct catactgctg gcgatcgtca tagccattaa cgtctttgtc
    22561 gcccgtaaat gcggcttcaa taaagccgac gaaatcacta ttgtcttctg cggttcgaaa
    22621 aaaagcctgg ccaacgggat cccgatggcc aatattctgt ttccgacgtc agtgctgggt
    22681 atgatggtat taccgctgat gatcttccac cagatccaac tgatggtctg cgcagggctg
    22741 gcgcggcgct acaaacgcca gaccgagaag ttacaggcgc agcaggaaag ccgcgccgcg
    22801 aaagcttaaa gcgggcgttt caggggctgc accagttgcg tcagcccctc ggttttaatc
    22861 agcagcgtga tttgcatcaa ctcccctagt ttacccgccg gaaattgatc tttacgggca
    22921 aaccacagca aatactcttc cggaaggtcg atcaatcgac gtccctgata tttgccaaag
    22981 ggcatcacgg tgttggcgat ttcaagcagc tgctcttttt ccatctcagg cacccagtaa
    23041 gcggatcatt tccgcttcat caatcacggt aatacccagt tcctgcgctt tggccagttt
    23101 ggagcccgcc gcttcaccgg caatcaccag atcggttttc ttcgatacgc tgcctgccac
    23161 tttcgcgccc agagccacta aacgcgcttt agcgtcatcg cgggacatct ggctcaggct
    23221 accggttagt accacggttt taccggcaaa cgggctatcg atctcttgcg cattaatgac
    23281 taccggcgcg ggccagtgaa ccccttccgc cagtagctgc ccaatcacgt cacgattgct
    23341 ctcttcggca aaaaagttaa agacgtgcgt agcgaccaca atccccacgt cgggtacttt
    23401 ctgcaactcg tcaatggtgg cagcctgcag cgcctccagc gtgccgaagt acgccgccag
    23461 ccccgccgcc gtcgcttcac ccacttcacg gatgcccagc gcatagagaa aacgcgcaaa
    23521 agtcgtcgct ttggcttttt ccagcgcgtt aacaacattt tgcgcggact ttggccccat
    23581 tcggtccagg ccggtcagtt tacccgccgt cagacggaac agatccgctg gcgtatggac
    23641 atactccctt tccaccagtt ggtcgatgat cttatcgccc atcccgtcta catccatcgc
    23701 ccggcgcgac acaaaatgtt tcagcgactc tttacgctgc gcgccgcaaa tcagcccgcc
    23761 ggtacaacgg gtaacggctt cgccttcgac gcgctctacg tccgatccgc acaccggaca
    23821 gtgcgttgga aacacaatcg gacgcgtctc ttcagggcgt tcggacagaa ccacgttgac
    23881 cacctgaggg atcacatcgc ctgcccgacg gataaccacc ttatcgccaa tgcgcaagcc
    23941 aagccgctca atttcatcgg cattatgcaa cgtggcattg ctgaccagca caccagccac
    24001 ctgaaccggt tctagacgcg ccaccggcgt aatcgccccg gtgcgcccga cctgaaactc
    24061 aacgtcgcgc acaaaagtca tctgctcctg agcaggaaat ttaaacgcca ccgcccagcg
    24121 cggcgcgcgg gccacaaagc ccagctgttc ctgcaaagcc agcgagttga ccttaatcac
    24181 cacgccgtcg atatcaaaac cgagcgtggg gcgatctttt tcgacgttgt gataaaaatc
    24241 cagtactgcc tggggagaat cgcacagcgt cacgcgatcg ctgaccggta acccccacgc
    24301 tttaaattgc agcaaccgtc ccagatgcgt atccggcaac tctccgcctt ccagaatacc
    24361 gacgccgtag cagaaaaatg ttagcggtcg cttcgccgta atacgcggat cgagctgacg
    24421 caacgagccc gccgccgcgt tacgcggatt agcaaacact ttgccgccag tacggcgcgc
    24481 gtcttcattg atcttttcga acccggcctg cggtaaaaat acctctccgc gaacttcaag
    24541 acgcgccgga atgttatcgc cgtgcagctt taacggaatg gcgcgaatcg tgcgcacgtt
    24601 tgaagtgata tcttcaccgg tggtgccgtc gccacgcgtc gcagcgctca ccagcacgcc
    24661 gttttcatac agaatgctga ccgccaggcc atccagtttt agctcgcagc accagatgac
    24721 attttccgtg ctttttagac gatcctgcac tcgcttgtta aacgccagga agctttcttc
    24781 atcaaatacg ttatcgagcg acagcatcgg tacttcatgg cgaatctggt tgaatgccgt
    24841 cagcggcgcc gcgccaacgc gctgcgtggg cgaatccggc gtgataaggt ccggacgttg
    24901 cgcctccagc tctcgcagtt cccgcatcag gcggtcatat tcggcgtcga gaatctcggg
    24961 cgcatccatc acatgataca gatattcatg atggcgaagc gtggttcgca gttctgtcag
    25021 ttgttgttcg attggttcca tatcacacca tcaatgataa aaaacccccg acaggcgggg
    25081 gttacgttaa aaatgtcaca cctgcgttaa cctcaggcgt tagcgtccat cacctcgcgg
    25141 atgcggtcct gatattcgcg cagtttctgc ggcgtcatca tccgacgctg gtcatccagc
    25201 acgacgccac cgacctcatc agcgatatgc tgcgcggatt gcagcatcag cttgaaattc
    25261 tgcagcgcat cgccgtaaga cggtacctgc ataaagatag tgacgccagg cgtagtgaag
    25321 tccgtcattt caggatcgaa cgttcccgga ttgaccatat tcgcgagact gaacaaggcc
    25381 gggccgctgc cgtccgggct caaatgacga tggaaaatat tcatatcgcc aaatttaaag
    25441 cctgactgct gaatactgtt cagtaacact tcaccattaa gctcgctgcc atgatgggcc
    25501 gcgacgttca taatgatgac cgcctcttta cgctgcggtt tttccacaac cggcgcttct
    25561 tccactaccg gttccgcctc aaccacaggt tccgcaggct ggaaggtttg cgctgatggc
    25621 ggcggcgcgg gctgcgcaac aggctgcggc gcttgcgacg gcggtgcagg ctgctgttgc
    25681 ggcggctgta ccggcggcgc agatggctga acctgctgag gctgcggcgc aggttggacc
    25741 ggttgctgaa ccggctgttg catcggcgct tgcggctgcg gcggcgccgc tggacgcggt
    25801 tgcgcagacg cataaggcgg ctggtactgg tgttgcggcg actgacgagg ggcatcatgc
    25861 tcctgcgact ggccgggggc atgatttacg cggtgaacac gaacttcacc cacgccttcg
    25921 tcttcttcga catcgtcgtc atacgagtcg tcgtcgcgtt tcgatttcat gcgttttagt
    25981 ggacgatcgc ggaacataga agatcgttct ttacggctgg tccagaaacc atgtaccagt
    26041 aaagcgatta tggcgatcgc gccaacaatg attaatatca gacgcaaatc ctgcatcatt
    26101 atattctctg ttgttctaac accttgccac cacggcaaac atttactcac taagagtatt
    26161 tgccgattac gtcaagtgca agtgtactgt tggctttcgc agcataaaga tgaaggaaaa
    26221 tgtgcttttt gctgtttttt cgaacatttc cgaactatcc accgtctgat aaccgggtaa
    26281 gatatcccac gtttacccag ggctttaaga aaaaggagta tgtcctgaat atggtttcat
    26341 catccacaac cgtaccacgt agcggcgtct attatttctc gcaaggatgg aagttagtca
    26401 ccctaccggg aatccgccgc tttgttattt tacctttgct ggtcaatatt gtgctgatgg
    26461 gcggcgcatt ttggtggctg tttacccagc ttgacgcctg gataccttcg ttgatgagtc
    26521 atgtgccgga ctggctgcaa tggctgagct atctgctgtg gccgattgcg gttatctctg
    26581 ttctgttggt ctttggctat tttttctcta ccctcgccaa ctggatcgcc gcgccgttta
    26641 acggcctttt agccgaacag cttgaggcgc ggttaaccgg cgctacgccg ccagataccg
    26701 gcatactcgg catcatgaaa gatgtaccgc gcattatgaa acgtgaatgg caaaagctgg
    26761 cgtggtatct gccgcgcgct attgtgctgc tggttctcta ttttattcct ggcattggcc
    26821 aaaccatcgc gccggtgctg tggtttttgt tcagcgcctg gatgctggcg atccagtatt
    26881 gcgactaccc gtttgataac cacaaagtgc cgtttaaaac gatgcgcgcc gcgttgcgca
    26941 cgcagaaggt ggcgaatatg caatttggcg cgctcaccag cctctttacg atgattccgg
    27001 tgcttaacct tttcattatg cctgtcgccg tctgtggcgc gacggcaatg tgggttgatt
    27061 gctggcgtgc taaacacgcg ttatggaaat aacgtaaaaa tgtataaata agagatggct
    27121 tagagcctat cccaccaagc gttattggcg cagccagttt ggacacggac agcgcgcaaa
    27181 aaccggagcg tacacgtagt acgtgaggtt tgactcgcta cgctcgccct tcgggccgcc
    27241 gcaagcggcg ttcaaaacgc taatgcgttt tggcgagcac tgcccaagac caaaatggca
    27301 agtaaaatag ccctaatggg ataggctctt atgctgtctc ttattccata ctgataacca
    27361 ttattcccca tcagcatata gatatgcgaa atccttactt ccccatatct ggctggaagg
    27421 tatgctggga aggtatccca atttcataca gttaaggaca ggccatgagt aagatttatg
    27481 aagataactc gctgactatc ggtcatacgc cgctggttcg actgaatcgt atcggtaatg
    27541 gacgcattct ggcgaaggtg gagtcgcgca acccgagctt cagcgtcaag tgccgtatcg
    27601 gcgccaatat gatttgggat gccgaaaagc gtggcgtact gaaacctggc gtggaactgg
    27661 tggagccgac cagcggcaat accggtattg cgctggcgta tgtcgccgcc gcgcgcggtt
    27721 acaaactcac cctgaccatg ccggaaacca tgagcattga acgccgcaag ctactcaaag
    27781 cattaggcgc gaatctggtg ctgaccgaag gggcgaaagg gatgaaaggc gctattcaga
    27841 aagccgaaga aattgtcgcc agcgatccgc aaaaatatct cctgctccag cagttcagca
    27901 accctgccaa cccggaaatc catgaaaaaa ccaccggccc ggaaatctgg gaagacaccg
    27961 atggtcaggt ggatgtgttt atctccggcg tcggcactgg cggtacgtta accggcgtca
    28021 cgcgttatat caaagggacg aagggtaaaa ccgatcttat caccgttgcg gtagaaccca
    28081 ctgactcccc ggttatcgcc caagcgctgg ctggtgaaga gatcaaaccg ggcccacata
    28141 aaattcaggg catcggcgca ggcttcatcc cgggcaacct ggatctgaaa ctgattgata
    28201 aagtggttgg catcaccaat gaagaagcca tttctaccgc gcgccgtctg atggaagagg
    28261 aaggtattct ggcgggaatt tcttccggcg ccgcggttgc tgcagcgctt aagctgcagg
    28321 aagatgaaag ctttaccaat aagaatattg tggttatcct accctcatca ggtgagcgtt
    28381 atctgagcac cgcgttgttc gccgatctct ttactgagaa agaactgcaa cagtgatgcc
    28441 agcatgttaa aaacgcgtaa aaaagcacct ttttgggtgc ttttttgtgg cctgcttcaa
    28501 actttcacct cacctggcat tgattcaccc tgccggaact ggtatttaac cagactaatt
    28561 attttgatgc gcgaaattaa tcgttacagg aaaagcgtta gctgaatcga ttttatgatt
    28621 tggttcaact cttcctttcg cggcataatg tttaatgacg agcgaaacgt cagcggccat
    28681 aagttgccag caacggattg cgtagaacac cttttgtgtc gcgtcccgtt tacgccggcg
    28741 ctaacaatac aggctaaagt tgagccgcca ggctagactt tagttccaca acactaaacc
    28801 tataagttgg ggaaatacaa tgttccagca agaagttacc attaccgctc cgaacggtct
    28861 gcacacccgc cctgctgctc agtttgttaa agaagcaaaa ggcttcactt ctgagattac
    28921 tgtgacttcc aacggcaaaa gcgccagcgc gaaaagcctg tttaaactgc agactctggg
    28981 cctgactcaa ggcaccgtcg tcaccatctc cgcagaaggt gaagatgagc agaaagcggt
    29041 tgaacatctg gtcaaactga tggcggaact cgagtaagtt tttttccggg ttcttttaaa
    29101 aatcagtcac aagtaaggta gggttatgat ttcaggcatt ttagcatccc cgggtatcgc
    29161 tttcggcaaa gcactgctgc tgaaagaaga cgaaatcgtc attgaccgga aaaaaatttc
    29221 tgccgacaag gttgatcagg aagttgaacg ttttctgagc ggtcgtgcca aggcatctgc
    29281 gcaactggaa gcgatcaaga caaaagctgg tgaaacgttc ggtgaagaaa aagaagccat
    29341 ctttgaaggg catattatgc tgctcgaaga tgaggagctg gagcaggaaa tcatagccct
    29401 gattaaagat aagcacatga cggctgacgc agccgcacat gaagttatcg aaggtcaggc
    29461 cactgccctg gaagaactgg atgacgaata cctgaaagag cgtgcggctg acgtacgtga
    29521 tatcggtaag cgcctgctgc gcaacatcct gggtctggcc attatcgatc tgagcgcgat
    29581 tcaggaagaa gttatcctgg ttgccgctga cctgacgccg tcagaaaccg cacagctgaa
    29641 cctgcagaaa gtgctgggct tcatcaccga cgcgggcgga cgcacgtctc atacctccat
    29701 catggcgcgt tctctggaac tgccagcgat cgtaggtacc ggtagcgtca ccgctcaggt
    29761 gaaaaacggc gactatctga ttctggatgc cgtaaacaac caggtttacg tcaacccgac
    29821 caacgatgtt attgagcaac tgcgcgccgt ccaggagcag gttgcgaccg agaaagcgga
    29881 actcgcaaaa ctgaaagatc tgccggcaat cacgctggat ggacatcagg ttgaagtttg
    29941 cgccaacatc ggtaccgttc gtgacgttga aggcgctgag cgtaacggcg cggaaggcgt
    30001 tggtctgtat cgtactgaat tcctgttcat ggatcgcgac gcgctgccga cggaagaaga
    30061 gcagtttgcc gcctataaag cggtcgctga agcgtgcggc tcgcaggcgg ttatcgtccg
    30121 taccatggac attggcggcg acaaagagct gccatacatg aacttcccga aagaagagaa
    30181 cccgttcctg ggctggcgcg ccgtgcgtat cgccatggat cgcaaagaga tcctgcgtga
    30241 ccaggttcgc gcgattctgc gtgcctccgc tttcggtaaa ttgcgcatta tgttcccgat
    30301 gatcatctct gttgaagaag ttcgcgcgct gcgcaaagag attgaaatct acaaacagga
    30361 actgcgtgac gaaggtaaag catttgacga aagcattgag attggcgtga tggtggaaac
    30421 accggctgcg gcgacaattg cgcgtcattt agccaaagaa gttgatttct ttagtatcgg
    30481 caccaatgat ttaacgcagt acaccctggc agttgaccgt ggtaatgata tgatttcaca
    30541 cctttaccag ccaatgtcac cgtccgtact gaacttgatc aagcaagtta ttgatgcttc
    30601 tcatgcagaa ggtaaatgga ctggcatgtg tggtgagctt gcaggcgacg aacgtgctac
    30661 acttctgttg ctggggatgg gtctggacga attctctatg agcgccattt ctatcccgcg
    30721 cattaagaag attatccgta acacgaactt cgaagatgcg aaggtgttag cagagcaggc
    30781 tcttgctcaa ccgacaacgg acgagttaat gacgctggtt aacaagttca ttgaagaaaa
    30841 aacaatctgc taatccacga gatgcggccc aatttactgc ttaggagaag atcatgggtt
    30901 tgttcgataa actaaaatct ctggtttctg atgataagaa agacaccgga actattgaga
    30961 ttgttgcccc gctctctggc gagatcgtca acatcgaaga cgtgccggat gtagtttttg
    31021 ctgaaaaaat cgttggtgat ggcatcgcta tcaaaccaac cggtaacaaa atggtcgccc
    31081 ctgttgacgg taccatcggc aaaatctttg aaaccaacca tgcgttctct atcgaatccg
    31141 atagcggcat tgagctgttc gttcacttcg gtatcgacac cgttgagctg aaaggcgaag
    31201 gcttcaagcg tattgctgaa gaaggtcagc gcgtgaaagt tggcgatccg gtcatcgagt
    31261 tcgatctgcc gttgctggaa gaaaaagcca agtctaccct gactccggtt gttatctcca
    31321 acatggatga aatcaaagaa ctgatcaaac tgtccggtag cgtgaccgtg ggtgaaactc
    31381 cggttatccg cattaagaag taattcttgc cgcagtgaag aatggcgcct ttgggcgcca
    31441 ttttttttgc ctgtacttgc gccgccatcc ggcgatggtg cggcgcactg cctgatggcg
    31501 ctacgcttat caggcctaca aggttgcgaa catttcagcg ccaatccacg ggttacaact
    31561 gcgaggtcac cgggcgaaag cacttctcgc gcatcaggat cttcatccca tccgggccac
    31621 tctccagtat cctgcgttcg gaatcggaca cttgcaactc gcactgatag ccgccagtga
    31681 tgccaaacat cgctcgcgcc acgcagatat cttccagcgc gtccagcccg ctcgtttcaa
    31741 aatgccccac gatacgcccc tgctggcgaa ccaccagccg ataactcttc atcgcgcctc
    31801 ccctgccggc ggcagaatta actcatcaca gccacactgc tgtgtccagg tcatcacctc
    31861 cagcacgcgc tgcgccgcat cttttgccgc ggtcgtcagt ttttttccct gcacaatacc
    31921 gctgaccagc tcggcgcaga agagatctcc cgtccctttt aactccgtcg ccacccgcgg
    31981 atgggcaaag acctccacga cctgcgcggt aacgacggca accgttatgg tctccagaga
    32041 ttcgcccggc gcgctggtga taaccaccca tttcagcgta tcggaaagca gcgattgcgc
    32101 cgccgccacc gcctcttcca gcgtgcgaca cggtttacca ctcagcatct ccagctcaaa
    32161 tacgttcggc gttagcccct gcgcctgcgg caacaaatgt gtgcgataag cctgcggaat
    32221 ttccgcctgc acatacattc cactgtcggt atcgccaatg acgggatcaa caagaataca
    32281 cacctccgga tgcgaagccc ggatcgccat tagccacttc gaaagcaaga caatttggtc
    32341 tgcgctgccc atgtaaccgg tggtaatcgc ttttaattca cgtagcgcat cgcgctcatt
    32401 caacgccgta aggtagcctg caaaccactc ggcgggaata atgccgccat aaaacgtttt
    32461 atagtgcggc gtattgctga acaacaccgt cgggaccgcc gtcacgcgta atccctgcgc
    32521 tttaatggcc ggaacagcga tactgttgcc tacgctgccg tacacaacct gtgactggac
    32581 ggcgacgata tcggtctgta acgcccgatg gttgtcgtcg aagagcactg actgaatatc
    32641 actctcttgt cccataaaat tttcctctcg ctggacagca ggctaccgcc tcattatcat
    32701 tgtcatatgc taaaattcat tttgtcatag gtcaataatg atcgacggaa aaaccgctaa
    32761 cgaaattttt gacagtatcc gtcaacacat tatcgccggc acgttacggg cgaaggattc
    32821 gctcccgccg gtacgggagc tggcaagcga attaaaggtg aaccgcaata ccgtcgcagc
    32881 ggcgtataaa cggctgataa cggcgggact ggcgcaaagt ttaggccgca atgggacggt
    32941 gattaaaggc agtccgtctc ccgtagcgtt ggaaggcggc gatccgcata cgcctctgca
    33001 cgacctttcc ggcggcaatc ccgatccgca gcgtctgcct gaccttagcc gttattttgc
    33061 ccgtctcagc cgcacgccgc atctctacgg cgatgcgccc gtttcccctg aactacacgc
    33121 ctgggcggcg cgctggctac gggatgccac ccccgtcgca ggcgaaattg atatcaccag
    33181 cggagctatc gacgctatcg aaagactgct ttgcgcgcat ctgctgccgg gcgacagcgt
    33241 tgcggtggaa gatccctgtt ttttaagcag tatcaatatg ctgcgctatg ccggttttag
    33301 cgccagcccg gtcagtgtgg atagcgaagg aatgcagcct gaaaagctgg agcaggcgct
    33361 aaaccagggc gcgcgggcag tgatcttaac gccgcgcgca cacaacccta ccggctgtag
    33421 cctgagcgct cgccgtgccg ctgcgctgca aaatatactg gcgcgttacc ctcaggtact
    33481 ggtcattatc gacgatcact tcgccctgct ttcttcgtcg ccctggcagc cggttattgc
    33541 gcagacaacg caacactggg cggtgatacg ctccgtttcc aaagccctcg gccccgattt
    33601 acgtcttgct attgtcgcca gcgacagctc gacctcggca aaacttcggc tgcggctaaa
    33661 tgccggtagt cagtgggtca gccatctgtt acaggatctg gtctacgcct gcctgaccga
    33721 ccctgagtat cagcacaggc tggcgcaaac gcggctgttt tacgccaccc ggcaacaaaa
    33781 actggcccgc gccctacagc aatatggcat cgccatttct cccggcgacg gcgtgaatgc
    33841 ctggctcccg ctggacaccc atagccaggc taccgcgttt acgctggcaa aatccggctg
    33901 gctggtacgt gagggcgaag cctttggcgt aagcgcgccg tctcacggtc tacgtatcac
    33961 gctgtcgaca ttaaatgacg gcgagatcaa cacgctggcg gctgatatcc atcaggcgct
    34021 aaatcgctaa caggagaaaa taacgtgcga gttcattttg ttatccatga gtcgtttgaa
    34081 tccgctggcg cttatctgaa atgggctgaa gatcgcggtt ataccatttc atggtcgcgc
    34141 gtctatgccg gagaagcgct accgcccaat gcagatgagt tcgatatgct cgtggtattt
    34201 ggcggtccgc agtcgccgcg caccacccgc gaagagtgcc cgtactttga ttctcaggcc
    34261 gagcaacatc tgattaacca ggcgatttcg gcacgaaaaa tcgtggtggg gatctgtttg
    34321 ggctcgcagt taattggcga agcgctgggc gccaaggtgt gccaaagtcc ggaaaaagag
    34381 atcggtcact acccaatcgt cctgaccgag gcaggccaac agcacccgct gttcaaccat
    34441 ttcggctccc cgcttatcgt cggtcactgg cataacgaca tgccggggtt aaccgaccag
    34501 gcgataattc ttgctaccag tgagggctgc ccgcgacaaa tcgtgcagta cggcaatttt
    34561 gtctacggct tccagtgtca tatggaattt accgtcgagg cggttgaagg attaatccaa
    34621 cattcgcagc aggagctggc cgacgcgcaa gggaagcgtt ttatccgctc ggtcgccgag
    34681 atgcgcgcat ggaattatca gcagatgaat gaaaagctgt ggcgttttct ggatgaactc
    34741 acgctggcgc actcacagaa ataaccacac caggagtgca acttattacc cggctaacgg
    34801 tctgaggtgc agtgattatt gcatgaaaaa ggattttacc atgaagaaaa ttgtctgcgc
    34861 cgtcgtcgcg ctcctgctga ccctccccgc ctgggcgaag ctaaacgccc atgaagaagc
    34921 gcgcattaac gccatgctta atgtgctggc gcagaaaaag gatctgacct tcgttcgtaa
    34981 cggtgatgcg cataactgcg aggaagccgt atcgcacctg cgcttaaaac tgggtaacac
    35041 gcgcaatcgt atcgacaccg ctgaacagtt tatcgataaa gtcgcgtcgt cgtcgtccat
    35101 caccggaaaa ccctatatcg ttaaaattcc tggtaaaagc gatgaaaacg cgcagcctta
    35161 tttacatgca cttattgcgg aaacggataa aacgctataa cacacgggtg tcatacgacg
    35221 atggcacctc gtttaaatcc ctgccccctg gctgaaatgc tcttcaccaa acacgccggt
    35281 agacaagtaa cggtcgccgc gatcgcagat gatcgccacc actatcgcgc cgggcgtggc
    35341 tcgtgcgacg cgtaacgcgc ccgctaccgc gccgccggag ctgacgccgc agaaaatccc
    35401 ttcacgaacc gccagttcac gcatggtgtt ttcggcatca ttctgatgaa tatccagcac
    35461 ctcatccacc agcgaggcgt taaatatgcc cggcatatat tccgtaggcc agcggcgaat
    35521 gcccggaata ctgctgccct cttccggttg caggccaacg atggtgaccg ttttttcctg
    35581 ctcgcgcaga aaacgcgaca cgccggtaat ggtgccggtc gtgcccatgc tggagacaaa
    35641 atgggtgatg cgacctgacg tttgccgcca gatttccggg ccggtggtcg tgtagtgggc
    35701 gtagggatta tcaggattat taaactgatc gagcagttta ccttctccgc gctcagacat
    35761 agcgagcgct aaatcgcgcg ccccttccat tccctgctct ttagtgacca gaatcagttc
    35821 cgcgccatag gcccgcattg ccgcccgacg ctcctggctc atgttgtccg gcatcaacag
    35881 cttcatgcga taacctttca gcgcggcgat catcgccagc gcaatgccag tgttgccgct
    35941 ggtcgcttca atcagggcat cgcccggttt aatttccccg cgcttttccg cctcgacaat
    36001 catcgatagc gccgcgcgat ctttcaccga tcctgccgga ttattgcctt ccagcttgac
    36061 ccagatttca ctgccgttat ccggccccag ccgttgtaat ttgaccagcg gcgtattgcc
    36121 gatggtttgt tctaatgtat tcacgttttc agctcaataa aaatgccggg tggcgctgtg
    36181 cttacccggc ctacaaaatc acgatatacg ctgtaggccc ggtaagcgaa gcgccaccgg
    36241 gcgataacta tgcaaattaa cctatcaggc agactccgca agagcaagcg cctcatgggg
    36301 ctcaatacgc tggtcgccat gatagagacg tgcgttctgt aagccgacaa acaaacgctc
    36361 gccgcgctgc gggacgtcgt cacccgccat caccaccgtc agcggatcgt gataccaccc
    36421 cagcggctgt accactaact gtgtatagtg acctttcggg cttgcctcaa tgacctgtac
    36481 tggtagcgga gaatccaggc tggtgcggcg gctgatatcc acctcccacg gacgcaggaa
    36541 cagatcgacc ggcccttggt acgcgggcgt ataacccagc ggccagcgat gcgcgccaac
    36601 gtgaaactgc ccgccgcgga cggtgcctgt caggcggttc acctcgccca taaactccag
    36661 tacgaagcgg gttgccggtt cacgccacac ccgatccggc gcgtcagcct gttcgatatt
    36721 gccctgactc attaccacca cccgatccgc cacttccgtc gcttcttcct gatcgtgggt
    36781 gacaaagacg ctggtgaatt tcagttcttc atgtagctgg cgcaaccagc gacgtaactc
    36841 tttacgtacc tgggcatcca gcgcgccaaa cggttcatcc agcagtagaa tttgcggttc
    36901 tacggcaagc gcgcgcgcca gcgccacgcg ctgtttttgt ccgccggaaa gctgggcggg
    36961 gaagcgatcc gcgaggtgcg ccagttgcac catctccagc aattgcgtca ctttcgtttt
    37021 aatagccgcc gcagttgggc ggtcgcgtcg cggcagcacc gtcaggccaa aagcgatgtt
    37081 gtcaaacacc gtcatatggc gaaacagcgc atagtgctga aacacaaaac cgactttacg
    37141 ctcacgcgcg tgcaggcggc taacgtccgt accgtggaaa cgaatatggc cgctggactg
    37201 atgttccagc ccggcaataa tgcgcagcag cgtcgttttg ccggaaccag acggccccaa
    37261 caaggcaacc atctggccgg aaggaatatc cagcgagata tcattcagta cctgagtgcg
    37321 accaaacgat ttcttaattc tggcgatctc aatgctcatg attttcctcc tgttgcgcgc
    37381 gtttttcctg attctccaga cgccattgca acatgctctt caaaaacagg gtaataatcg
    37441 ccattagcgt caacaatgcg gcggcggtaa aggagccgac ggtgttgtag tcctgctcca
    37501 gtaattcaat ctgtaacggt agcgataacg tttcgccgcg aatcgagccg gacaccaccg
    37561 acaccgcgcc aaactcgcca atcgcgcggg cgttggttaa taccacgccg tagagtagcg
    37621 cccagcgaat attcggcaac gtcacgcggc gaaacatttg ccagccggat gcgcccagta
    37681 aaatcgccgc ctcatcttcc tggctgccct ggctgagcat cactggcacc agttcgcgca
    37741 ccacaaacgg gcaggtgaca aaaatagtga ccagtaccat ccccggccag gagaacatca
    37801 tttgcaaatt atgctcatcc agccagccgc ccaacgggcc gttggaacca taaaacaaca
    37861 gataaaccag accggccacc accggtgaga cggcaaaggg aatatccagc agggtcagca
    37921 gtagctgacg tccggggaag ttaaagcgcg tcaccagcca cgccagcaga ataccgaaca
    37981 ccagattcat cggcactgcg atcaaggcaa tcaacaccgt cagccagatg gcgtgcagca
    38041 tgtccggatc ggccagattt tgcagtaccg gcattaaccc tttgctgaac gcctgcacga
    38101 agatgtaaat catcggcacc agcaggataa aggccgaaac gagcatcccg acgccaatca
    38161 aaaaccattt tccccagtta atacggggga cgtcgtatcg cttcaattga gtcacttccg
    38221 ccattaatga cctaccacac gtcgaccaaa gcgactttgc agagtgttaa ttgagaacag
    38281 cagcagcagt gatgccgcaa ggatcaccga ggcaatggcg ctggcagctg ggtaatcaaa
    38341 ctcctgcaaa cgcacaaaaa tcatcagcga ggtcacttct gttttccagg cgatatttcc
    38401 ggcgataaaa atcaccgcgc caaactcgcc caggctacgg gtaaaagaga gcgccacgcc
    38461 ggcaatcagc gcaggcgaca gctcaggcag cacgactttg cgaaaacttt gcaggcgggt
    38521 ggcccccagc gtttgtgccg cttcttcata ttccggcccc agctcttcca gtaccggctg
    38581 gacggtgcgc accacaaatg gaatgctggt aaaggccatc gccaccgcaa taccgagcca
    38641 ggtataggtc actttgatat caaactgcgc aagaaactga ccgtagaaac cgttcactga
    38701 gaacagcgag gccagcgtta accccgccac cgctgtcggc agcgcaaatg gcagatccat
    38761 cagcgcatcc agtaacgtgc gccctggaaa acggtagcgg gttaaaatcc acgccatcag
    38821 caggccaaac acgccattaa aaatcgacgc cacaaatgcc gccagcagcg tcactttata
    38881 agcagccacc acctgtgggt tggtcacgac atcccagtat tgcgaccagc tcatctgtga
    38941 gagctgcatc accagcgcgc tcaacggcaa cagcaggatc aggcagacaa acagcaaact
    39001 ggtgccgagg cttaacgtaa agccgggcag cacgcgtcgg gaagaaacgg caagcattac
    39061 ttacgccccg ccgccaacag tttgtccagc tcgccgccgc tggcaaagtg cgttttcatc
    39121 acctcaggcc acgtgccaaa cttgtcttcc acgcggaaca gtccggtttg cgggaattta
    39181 tctgcttgct tgcccatgat ttccgggtta ttcacgcggt agtagtaatg ggtaatgatg
    39241 gtctgcgcct gcgggctata cagccagttc aggtaagctt tggcggcttt ttctgtgccg
    39301 ttggccttca cgtatttatc cacccaggca accgggaatt cagcaagaat gttcgttttc
    39361 gggatcacca cttcaaatcc ctgggcttca tattgtttgc ggatgttgtt cacttccgat
    39421 tcaaaactaa tcagcacatc gcccagacca cgctcggcaa aggtagtcgt agcgccgcga
    39481 ccgccggtat caaacacttc gacgtttttc aggaactggg tcataaactg ttcggttttg
    39541 gctttatcgc cgccgtccgc gttatccgcc gcgccccatg ccgccagata cgtgtaacgg
    39601 gcgttgccgg aggttttcgg gttagggaaa atcagcttca cgtcggaacg tacaagatcg
    39661 ctccagtcgt gaatattttt cgggttcccc ttgcgcacta ggaagcccat agtggaatag
    39721 aatggcgaac tgttgttcgg cagacggctt tgccagtcgg cagggatcag tttgccttta
    39781 tcatgaagaa tctgtacgtc ggtcacctga ttgtaggtca cgacgtctgc cttcagtccc
    39841 tgcaaaatcg ccagcgcctg ttttgatgac ccggcatgag actgcttaat cgtcagctta
    39901 tcgccgccgt tatccttcgc ccattgttgc tcaaacggcg ggttaagggc ggcaaacagc
    39961 tcgcgggaga catcgtatga gctgttcagc agctccgttg cctgcgcctg ccctgccagt
    40021 aacagcattg ctgccagcgt caggagtctc tttttcagta agttaacggc cattgcgcac
    40081 ccttataaat ttaatgactt tcttatggtc atcatattta taaccagcgc taaaggagta
    40141 acggttttat ataccgtttg atgatttgaa agttgaaaag ggaataagag aatccctccc
    40201 cacgcggcgt gaggaggaga ccggcatcaa tcagacgcct acgcttacgc tttcaggcag
    40261 ggtactgccg ccatcaatga cgttttgcgt tccggtaaga tagctggact catcggaagc
    40321 cagaaatgcc gccagttccc ctacttccag cggatcggca agacggcgta gcggaatggc
    40381 ttttgccatt tccgttaata ccgattccgg atcgtcaggg ttagactgac gggcaatgct
    40441 ttccgccatc ggcgttctta cataaccggg gcaaatggca ttcacacgaa taccggactg
    40501 cgcgtactct accgccagcg atttggttaa accgacaatg gcggcttttg acagcgcata
    40561 ggccgtttca cccgggtccg ccaccatatc tcccgtgacg gaagacatca tcacaatgcg
    40621 gccatcttta cgtttgatca tctccggcag gacggctttg gtgacgttcc agacaccttt
    40681 aatattaata tcaatgtgga aatcgcgatc ttcttcactc atatcgagga agttgcccag
    40741 acggcacacg ccagcgttat tcaccaaaat atcaattcta ccttcagtct ctttggcgcg
    40801 cgcaaccgcc gcctgcaccg aagcaaaatc tctgacgtcg gctttaacgg cagtacagcg
    40861 atgcccgcgc ccgcccagct catccgccag cttttcaatc tcatcggaga tatccagcaa
    40921 gattaagttc gcgccgtggc gtgcgaatac gcgagcgatc ccttcgccaa tgccctgcga
    40981 tgcgcccgta atcaatgctg tcttgcccgt gagtttaccc attttcaatg tctccttttg
    41041 aatatggagt cttacactcc attaacactg aaaatacagt aataacaaat aagtgctgag
    41101 gaatagctca ctaattcagg taaatattag gtaaaaaaat ccccgcggag gcggggatgg
    41161 gcatttttat gctgttctgc ctgatggcgc ggcgcttgtc aggcctacca atcgtaggtc
    41221 gaataaagcg tttgcgctgc catccgacag ggttttactt atagcgctaa caggcgatcc
    41281 agcgacggcg caaaatagta gccgccagtc accggtttgg tgaagcgcag cattgcgtcg
    41341 cgtttaccgt cggtatcgcc gaacatactc agaagctgct gttcgatatt gtgcaggcgt
    41401 gcgcagtaag cgcagaaata gagaccatga gtaccgctgg cggtgccgta tggcaggctc
    41461 tgacgcacaa tcttcagccc tttgccatct tctttgagat cgacgcggct caggtgagat
    41521 gttgccggac gcgcatcgcc gtcaatctct tcattggctt ctttggtacg cccgatcatc
    41581 atctcctgat cgtgaatact catccggtta agttgcttga gattgtgttc ccaacgctgc
    41641 acgaacacat aactgccgcc ggcatccacg ccatctttga tcaccgccac ttcacgacgc
    41701 gtctcttcgc ccgccgggtt ctctgtcccg tcgacaaagc cgctcagatc gcgttcttcc
    41761 acccaacgga agccgtgaac ttcttctttc acgtcgatac agtcgccgaa ggcttccatc
    41821 gccgcctgag caacagaaaa attcacatcg tggcgcaggg aaaggatatg gatcagcacg
    41881 tcatactgcg tggctggcgc cagcccttta ccataaggaa taaaatcttt cagttcttcc
    41941 gccccgacgc cgccactcag ggcacgccag gtattgttgc caaacgccac aacggcccca
    42001 agatgggcgt ccggaaattt gacttcgaag gtcgccagtt tatcggcaaa tgttctgctg
    42061 gccgcgcgca gggcgtccag gtcgcctttt acattggctt caatccaaat tgccgcacgg
    42121 caatgttccg gcaaaatgcc actttgaacc tgagacatga ttcctcctga aaatgagaat
    42181 gccacgcagt cgtggcatta atggaggtta ttttaccttg tttttaagcg aagcggtttg
    42241 ttcaggcgca aattaacgac gccagataat tttgcgcacg tcccagtttt ttaagacgtc
    42301 atcaggaggc attaagcctt ccggtccgct ccactcgccg gagaaaacat agctaatatg
    42361 ctgacttccc tcggctttac attcgacgct ggtatggcta tcgctggaaa ccggctcgca
    42421 gtgaccaaac gctttgctgt aaaggtcgct aaacggcgta ccgattttgc cccccgcggc
    42481 ggttgggata tcgctgtcca gcacatcaat acggctcacg gttccctgct cgccgttgat
    42541 caccatcgcg acgctgtcgc ccttcatcgc ttcgaaaaag cgcaccacgt tgccgttatc
    42601 ggttttcata ccgctacgca ggcgataatc gccatctaat gcctctgcaa tagccggctc
    42661 ttccagcggc gtggcggcgg tcagcgctcc cacgccttgc tcagtgactt ctgtcgagga
    42721 accaaaccag ttccatggat ttgcggcaga ccagttgacc gaggagagca tcgagcagcc
    42781 ggtcagcgcc agcggcagtg cgagtaaagt caaacgcagc gatttcatct cacttccttt
    42841 cttttattaa ttaacgttgg ttggagtacg ggttcgccaa aaagtgccgt tattctttct
    42901 caagggaaaa acaggcacgc aaacgttgat tggttaacag ccagatcagc gcgacgatgt
    42961 ccgccagcag cagcgccagc ccgacgccgt tgaccgggtc gccacccagc cacatcaccg
    43021 gcagccagca caacgacacc agttgagcga ggatcaggag tccgcgcagc cagcgccaca
    43081 caccaggaac cgcttcacgc cgcccgctga gtaaaaacgc cactaccgcc ggaacgccgg
    43141 gcaacagccc cagccaaaaa ttatcatggt cgggataaaa aaagtttaac aaagtattac
    43201 cctgtccacg ggatgaaccg gcaatgacaa agagtaccca ggcgcgcgcc tgaagtagca
    43261 gtacgcacca gaacagaaac ggcaggcgta aacatccgtg tacatcataa tcggctggat
    43321 gaaactcagt actcttcatc ttcaatcagg cgtttaccca aacttagggc gtcagaatgc
    43381 tcatacccca gacgttcata catgcccagc acaacgtcgt tatcatcacg caccataatt
    43441 tggattttcg gacacccgcg ggcgatgagt tttttttcca gccggttaag cagcgcattc
    43501 gcaatgccgc gcccgcggaa ctccgggtga acgcccaggt aatacgccga gccgcgatgc
    43561 ccgtcataac cgcccattac cgtaccgacg acttcgccgc taacttccgc aacgaggaac
    43621 aagctgacat cgtgattcac cttgcgttca atatccattt caggatcgtt ccatggacgc
    43681 agcaggtcgc aacgctccca gagggtaatc acctcttcga aatcttcctg gcgaaaaacg
    43741 cgtatttcca tggtattcgt tgccttttcg ggtggaaaaa ccaagattat ggcgcaaaca
    43801 tctgattcag ccaatatctg acgcgatgta gcggaaaaaa tggcataatg gcgatgtgtc
    43861 acgtattgaa atgaaaagta aaacaattct catcaccaac cgtcgtaacg gattacgcga
    43921 tacgatataa catcttgaac ttaattttca caactcaggc cgtatgagca cttttaaact
    43981 cctaaaaact ctcacatcgc gccgccaggt actcaaaaca ggtctggcgg ccctgacgct
    44041 gtcaggtatg tcgcacgcaa tagccaaaga agaaacgcta aaaaccagta atggtcacag
    44101 caaacccaaa accaaaaaaa ccggcagtaa acggttggtg atgctcgacc ccggacacgg
    44161 cggcatcgat accggcgcga ttggccgcaa cggttctcag gaaaaacacg tcgtactggc
    44221 aattgccaaa aacgtacgcg ctattttgcg aaatcacgga atcgatgcgc gtttaacccg
    44281 gacaggggat acctttattc cgctgtacga tcgggtggaa atcgcccata agcacggcgc
    44341 ggatctgttt atgtctattc atgccgatgg ttttaccaat ccgaaagcgg cgggcgcttc
    44401 cgtttttgcg ctttccaacc gcggggccag tagcgccatg gcgaagtatc tctccgagcg
    44461 tgaaaaccgc gcggacgaag tggcgggtaa aaaagccact gaccgggatc atctattaca
    44521 acaagttttg tttgatctgg tgcaaaccga tacgattaaa aacagtctga cgctgggttc
    44581 gcatattctc aagaaaatca aacccataca taaattacac agccgcacta ccgaacaagc
    44641 ggctttcgtg gtgctaaaat caccgtcaat tccgtcggta ctggtcgaaa cctcgtttat
    44701 taccaatccg gaagaagaac gcctgctggg cacgacggcg tttcgccaga aaatcgctac
    44761 ggcgatcgcc aacggcatca tcagttattt tcactggttt gataatcaga aagcacacac
    44821 gaagaaacgg taatcatgaa acccgatgca catcacgtaa aacagtttct gctacgcctg
    44881 caggatgata tttgccaaac gttatccgct gtggatggcg caaactttat cgaagatagc
    44941 tggcgacgcg aagcgggcgg cggcggacgc agccgggtat tacgcaacgg cggaattttc
    45001 gaacaggcgg gcgttaattt ctctcacgtt cacggcgatg caatgcccgc gtccgccacc
    45061 gcacatcggc cagaactggc cgggcgtagt tttgaagcga tgggcgtatc gctggtggtg
    45121 catccgcaca atccgtatat tcccaccagc catgctaacg tgcgcttttt tattgccgaa
    45181 aaaccgggcg ccgatccggt gtggtggttt ggcggcgggt tcgatttaac gccctactac
    45241 ggctttgaag aggatgccgt tcactggcac cgcaccgccc gcgacctgtg ccagccgttt
    45301 ggcgacgatg tgtatccgcg ctataaaaag tggtgcgatg actacttttt cctcaagcat
    45361 cgtaacgagc agcgcggtat cggcggcctg ttttttgacg atttgaatac gccggatttc
    45421 gaccactgtt ttgcttttat gcaggcggtc ggtaacggct acaccgaggc gtatttaccg
    45481 attgtcgaac gacgcaaagc gatggtctgg ggagagcggg agcgtaattt tcaactttat
    45541 cgccgcggtc gctacgtgga gttcaatctg gtatgggaca gaggcaccct gtttggtctg
    45601 caaaccggcg ggcgcactga atctatcctg atgtcgatgc cgccgctggt gcgctgggag
    45661 tacgactggc agccggaagc gggtagcccg gaagcggcgc tgagcgagtt tattcaggta
    45721 cgcgactgga tttaacttat ttataaagta aaacaatgca aacaaataca cggaaagtag
    45781 taaccagtga cgccaaatgg catccccatc tgggtataag ttttattggc tgcctgcttg
    45841 ccattacgct agaaatatat tttgaagaaa gaatattcat ccctcatagc ggaggggtga
    45901 gcttcggtct gatcgtgctt ctggttatca atatggtgac catccctgtg gtcatggccc
    45961 tgatagcatt actctgcttt attattcata ttccgcgtaa aagcgttaac tgcatcttgc
    46021 tatgcctact ggcatgtatt ttgacgatag ccggtttgtt tatcgcctat ccggttggcc
    46081 gttgaataaa agcaggctcg tagaaataaa cgagttcatt gtagataaag aattcggata
    46141 accgcccgct gccgttatca ttagtaaaac agtacagtaa acactcgtag aatttgcagt
    46201 ggagcactac cgcatggacg agcgtattcc ttgtaaaaac ccgcaatgct cacatttcat
    46261 cctgccagca acggctgccc gcacggaggg ctattgcatg ccctgcgtcc aggcgcgcta
    46321 tcggcaagag caggaagaat atatccggaa aaacagaaaa acgatcgacg cgttcagtgg
    46381 cattaccaac cctgttgaaa tgcttaaact cgttcatgaa ccccgggaac acgatccgtt
    46441 aatcgagtgg attccctgcc ccattccgac cgatgagctt tacaaaaagc tctccgatga
    46501 tgaaagccgc gacatggtcg attatgcaga agaattattt gattccggat ggcaggagga
    46561 agctcaggaa attgcgctgt gcctggcggc atttacccag gccaatctgg ataatttcct
    46621 gcgccaagta ataaatgaag aggaactgga gctctcttca cccctacctt ttcaccgtgc
    46681 gccgcctgac gtacgcgacg cgcttttgca gaaggttgaa accgatgacg aaaaccgtga
    46741 tggcattctt tgcgccctgg cctggattgg cgatgaggtt gtcgttgagc attttaaccg
    46801 ctggcgccag gaaccacctg cgtggagtgc ttcacttcat atcctccctc atcgctatgc
    46861 tcaccaggcg ggatgggagc tcactgaaaa tggccgcagg cgcgatcttt actttacgca
    46921 atgtacccat ctggtaaaac aggcacctga acagccggcc gtttttcgcg ccgttgcaga
    46981 atatggtgaa aactgcccac actgttccct gccgctaatc aatctgtttg aggttgcgcc
    47041 gagcgccgtc ggcctaagca cgcagggttg gcccggtcaa attcgtattc tgacctgtca
    47101 gtgttgtacg gcatataaca ccgttttcgc caccgtcgat ccacaaggcc agccgcgatg
    47161 gtacgaaaaa aatgcgctct cgacgctggc ggtggagaat tcctctgact ggataacgct
    47221 accgcttgat gttctgcacc ccggggaatc ccgtttgccg ctattcgctg ctgaaatatt
    47281 tttacccacc accttctcac agctcggcgg ccatcccgca tgggttcagg atacagacta
    47341 tcccacgtgc ccaacgtgcg cgcaaacgat gatgtttctt gcgcagctaa gctatgaaga
    47401 tatcgaggaa gaggaatatg cggaaggaat gctttacggg tttatctgcc cctcctgcca
    47461 aacaacggca acgtcttatc agcaaacata aacgctcatc ctcatgatct gatgacaaaa
    47521 ctgttttgca cgttgtgcgc gcgcttcccc ggaggcggcg ctggcgcgcc ttgtccgggc
    47581 taccaaccac aaacagcagc gaatccgtag gcccggtaag gcgccagccg ccaccgggca
    47641 attcccgaca cgcgcacgtt atcagcaacc ggagagccta cccatcaata tcaagcccat
    47701 tgccgcatcc gttgatgcag cgtcaacgac ggtttttcgg caaataattg ctgataatcg
    47761 gtggcaaact gccccagatg ccagaatccc cactgcatcg cggcatctct gaccgtggtg
    47821 ctctgcgacc acgggctaat caactcccgg cgcactgcat tgaggcgaat acgtttcagc
    47881 cacgcattgg ggccaatgcc caaaatggcg tgaaacgcat tttgcagcgt gcgacggctt
    47941 acgtgtagct ggttacataa gtcgagcacc gtcagcggct ccgacatatt ttccagcaca
    48001 tattcccgcg cccgcgacag tagcctacga tatccctgat ggctgatgct ttcggcgcta
    48061 tgaatcggct tcgcctcttc cagcatcgtg cccatcgcca gcaacaaatt atcactcaag
    48121 accttacgca ccgcaggttg atgcagggtt tcaggactct cgctaaaggt ggccagcgcc
    48181 tgctgcacaa agccccacag cgccgcttta tgctgctctt ttacttccag cgctaactgg
    48241 ttacgcagca tatgcagcac cctttccggg ttatgcaaaa acgtggcctg acgggaaata
    48301 acatcttccg agataacgac gcccagaatg gtgtaatcat ccggcgtgct cagttcaaac
    48361 tcggtgcctc ccggtcgggt ggcaatctcg gcgctgccga gcccctgcgc gccaataaat
    48421 ccctgttcgc cgcgcgtcgc cggaatacca aaccagaaag agtttggcca aaccagacac
    48481 gactgacgca gcgccaggcc ggtgtattca cggaacacct gaatctcatc aagcaggatt
    48541 tccgtgaact cgccatgaaa tttacccagg tgtaactgat cgtagatctg ctgccaggcg
    48601 gtgatagtca gagcatgttc atagacatcc gtcgtccgtc gctgatgaac attgtccacc
    48661 tcgactctgg gcgtaagttt aacgtcttcg ggtaacgctt catgataaag atggtgcaaa
    48721 ttcgctgtac gggtcttttt catgatcttc tatgccggac gcccgccagg acgcccggcc
    48781 ctccgacaga ttaatttttg atgcgatagc gactactgcg tttacgcaac gctccgtcag
    48841 aaaagagttg ttccagcacg tttctggcct gctccagcgg ccagccaaaa tgcgcggcca
    48901 cctctcccgc cgtcattccc tggcgtactg atgccagcag cgccagtaac gcttcagcga
    48961 actcaggcgt tgcgggtacc tggggcgctt tctcagtcgg cgttgtcgca cgcgcaaacc
    49021 cgccaatcag ccactgggtg tcctcttccg gacgaccaat ttctttgcga ctaatcacac
    49081 ggcctgtgtg ctgcgcggcg gcgcttccgg catctagcgc cgcacgacac gccgccagat
    49141 cgccctccac caccagcgtg agcctgccag ggtcgagcac ttggtgactg agcaaacgca
    49201 cgttggccgc tttcagcatg gcatccgccg catcgacggc ggcgaccatt ccgtccactt
    49261 ccagtaatcc cagggcattg atcattggca gcctccgtta cgcacgctgg acagggttac
    49321 gggcgatatc cagcacggcg tcggtaaagg cgttgcaggc ggctttacac gcggcctggc
    49381 ttcccgttaa aaacgcggcc gaatagttgg tttccgacgg cggcggcacg taagtcacca
    49441 gttgaacgtc agcggatttc atcgccgcgt caatgccgaa tgtcgcttcc agcggcggcg
    49501 ccaccaggta ggccattgga tcgcccagcg cgatacctgc ggtagacgag aggtacgagc
    49561 cggtacgcga aaccacatgc gccaggaacg cggtattttc cgcatcgttc gcccactgga
    49621 acgccgcgcc gttttcaata ctggcgacca tcgcatccag accggcgcgc acttccgccg
    49681 ggttcggtcc gcccagcata atcaacactt caccggcggt aggcgacggc ccgtgagccg
    49741 ccccggcata gagggagcgg ccatagacta cttccaccat cgcctgtttg gtcgcttcgt
    49801 cagcggcaat ataggtcaca tcatcagaat ctgccgtgat gagtccgaga ctacgtatat
    49861 gtggcggtaa tttaagttcc cgcgcaaagc cgtcattcac ggaggcaatc acgcgcatgg
    49921 cagtcactga aggtcgaatc aaatctaatg caggcatgat gtctccttaa cgggtcatgt
    49981 tgatgccgga cgctttctgc tccagcatcc gtttggccaa atccacaatc acggcggcag
    50041 cttctactgg cggcgtcccc ccctgatgaa tgtttgaaat acaggttctg tcggcctcga
    50101 cggtggtcgc cacgcgcggg gaatagacgg cgtagcagga gaggctttcc gactgcccca
    50161 gccccggacg ttcgcccacc agcaggatga cgaccttcgc gccgagaatt tcgccaatct
    50221 gatcttcaat cttcacgcgg ccatagcgca caaagaacgg cgtgccgacg ttcagcccgg
    50281 cctgcttcag accggcaagc agcggcggca ggatctcttc atagttggcg gtgatcgcat
    50341 ccgtagagag gccatcggag accactacct gcacatccgg gttcatcacg cactgcgact
    50401 tcagcgcgtc aatggcttcc gggctcaggc gacgccccat atccgggcgc gtcaggtaca
    50461 ggtttttgtc gctgatctcc gaacgtactt ccagcagccc ttgcgctttg ccccactctt
    50521 ccggcacttc tttgagcacg gtgtctttcg aacgggagtg atccgccagg aagcgcaaca
    50581 gcgcctgggt gcgcggacgc ggcccggcac gacccgtaca gacgcgtgcc gcagtactgc
    50641 gacgcagttc ggtcagcacg tccgcacgat gcggattctc gacgccaatc caggcttttg
    50701 cctctgcgga acctaaatcc agcgcgcagc tttcggtcac cgtcggcgcg gcgcactgcg
    50761 gctttgcgcc ttcctgcgtt gacggcgcga cgggctgcgg tacgtcctgt cccattgacg
    50821 ccatcacgct acgtacaatt tcttcaatct gtttttgatc catggtgtta tccccgcgtc
    50881 atcagaagaa cagtgacgga tcgcccgccc gtttggtcag acgaccgttt gccataatgc
    50941 ccatcgtttc cagccagcgt tcaaactccg gcgacggccg taaattcagc aactgacgga
    51001 cggtggcggt atcgtggaaa gcggtagtct ggtagttgag catgatgtcg tcgccgagcg
    51061 gcatccccat gatgtagtta cagccggcag tggcgagcag aatcatcagg ttttcgttaa
    51121 ggttctggtc ggcgtcggca tggttggtat agcagcagtc gcagcccatc gagatgccgc
    51181 tcagcttgcc cataaagtga tcttcgagac cggcgcggat aatctgcctg tcgttgtaga
    51241 gatactccgg cccgataaag cccaccacgg tgttcaccag gaacggatcg tagtagcgag
    51301 ccagcccgta gttacgcgct tccatcgtca cctggtcggc accaaagttc gcaccagccg
    51361 acagcgccga gccctgtccg gtttcaaagt acaggcagtt ttccccggcg atgcggttga
    51421 actccgcccc cactgcccgc gcttcgtcga gcattgccag ctcgacaccg aactctttta
    51481 agcccttctc gctgccgcaa atgctctgga aaatcagtcc gcctggcgcg ccgcgacgaa
    51541 tcgcttcaat ctgggtggtg acgtgcgcca gcacgcagcc ctgggtcgga atattgaatt
    51601 tatcgataac gccgtaaacg gtgtcgagca cgcgggtcag gttctccacg tcatcggtca
    51661 ccgggttaac gccgatcacc gcatcgcctg cgccgaaaga aagcccttcg tagatttgcg
    51721 cggcgatact ctgcacatcg tcacgggtat cgttcggctg caaacggcag ctaaaggtgc
    51781 ccggaatacc gatggtggta ttggcttttt tgatcaccgg cattttctta ccgccgtaga
    51841 tcaggtcggc gttggagcag attttcgcca ctgccgccac cacttcggag gtcaggcctt
    51901 tgcgggtaaa cgcgatgtcg tccacggagg tttcatcgct cagtacgtat tcgcgcagtt
    51961 cgctgatgct ccagttttta atccgattat aggccgtttc gttgacgtca tcctgaatca
    52021 ggcgcgtcac gcagtcctct tcataggcaa tcaccggatt gttgcggata tccgccaccg
    52081 tcatttccga cagtacctgt tttgccgcta cgcgctcctg cgaacttgcc gcggcaaccc
    52141 cggccagcac atcccccgaa cgcagttcgt tggctttagc cagtacctct tttacatcct
    52201 taaactgata aacattgccg aacaatgtgg tctttagttt cataagtcgt tccctcagga
    52261 aggaaatgcg agtgatttca ccgtcaccgg cacaaccgat ccgccaaaaa gaggcgtacc
    52321 aatgtcgata tagtctcccg cccgcacgac cacctcatcg atgaccgcca gcggaagttg
    52381 cggtaactgt gggcgcaata acatgcccag cgctttacca aaatcctgct cggccaccac
    52441 cagcagggga tgtggattgg gataacgcgc gacaaaagcc gtcagcgcgt tgatgaccgt
    52501 gagtaatgcg gcgtaacgca ccggaagcgt ggagggaagc gccagcacgt aagcgtcggt
    52561 ttgcgggtcg agatcaagct ggagaagcgc ctgccgccag gcgttcacca aatcggcgtc
    52621 atcctgcggg atcgccaccg gcaggttgcg cagcggcagt tggacgtctt ccagccagat
    52681 agtactgccg gaaagcgaga gcgtatgggc ccccgcgcca atcaccgtgg cgcgtacggt
    52741 ttgcgccgga aactgcacgt tcatctcgcg cagacgcggg tgctcatgca gcgcggtcgc
    52801 cagcagcggc ccgatatcag aaaagcagaa cggatcggca ggttggttgc ggtagcattc
    52861 acctactcca ccggaaaggg tgatcacctc cggcgtaata tcggcgggca gcagcccggt
    52921 ttgcatcagc gattgcgcca gcggcgagag cgcgccagtg ataacctcga cgatgagatc
    52981 cgccatccgc cgcgccacct gccccaactg tgcggcagct aaggcgcgag catcagtacc
    53041 cgaaccgaac acctcatcga taatcatctg ccccggctga tgggcataaa ccacgcgccc
    53101 ctgagcgtcg gtttccagca ggcgaccacc gacgttaagg caggcggtgc cgctgacttt
    53161 tcccgcgtca aacagcgcgt agttagacgt gccgccgccg atatcaatat tcagcacccg
    53221 gcacatccgc tgctcagaca ggctttgcgc cccggcgccg taaccggcaa tgaccgattc
    53281 cagatgcggc ccggcgctgg cgaccacaaa gtcgcccagc gactgcgaga gcgccatgac
    53341 cgccggacgg gcgttgcggg ttttggcgct ttcgccggtg ataatgatag cccctgagtc
    53401 caccgattca ggcgcgatgc ctgcggcctg atactgagcc agaatcagcg ctttaagttc
    53461 tgcctctttc agaccgccct gcttatccac gggcgtaaag aagaccgggc tttgccagct
    53521 aatgtcgcgt ttgatgaatt cgtagcgcgg cacctgcgac accgccgcac ggttaaccaa
    53581 ctccaggcgc gagaagatca cctgcgtggt ggtggtgccg atatcgatac cgacgctcag
    53641 tagctggcga gtgttcacga ttgcgcctcc gcttcggttt tcacctgggc ggcgtcatct
    53701 ttcggcacca gcatcatcgc cacgccaatc gccgtcacgc cgccgatcag cttgccgaca
    53761 atcatcggga agatcatggc gttcatgttg gcagcggcga agcctaaatg gtcgaccagc
    53821 gcgaacgccg cagagacggc aaatgcgcag ttaatcactt tgccgcgggt atccatctgc
    53881 ttcatcatgc cgaacatggg gatattgttc gccagggtcg ctaccatgcc tgccgccgca
    53941 atattattta cgttcagcag cttaccgaca ttcatcaacg gtttttcaaa ccagcgggtc
    54001 agtaacagca ccatcggata cgcgccgagc agcacgcagg agatagagcc gatcacttca
    54061 atggcgcgca tcacttcgcc gggtttgtcg cctggcgcca taaagatcgg gtcgagcccc
    54121 ggaatcaact cccagcccaa caggaattta accaccgcag ccgccagacc gatggtgatc
    54181 agcgccacca gaaatttggc gaaaatctgg aaaccgttga tcattttttc cgggatgaac
    54241 ttcagcccca gcgctaccag caccgcgacg atcaataccg ggatcatgtt catcaggatc
    54301 agcgcgaagg taaactccac tggctgacca ttgatctgca cacctgagta catggcgatc
    54361 aacccccccg caatgcagcc aatgggaatg gtgacgatac ccgccagtac gccaagcgcc
    54421 aggtagcggc ggtcagacgg ttcgataatg ccgagcgcca ccggaatgga gaacacaatg
    54481 gtcggcccca tcatcgaccc aagtattaac cctgagtata gccacgccgc gacatcaccg
    54541 ccggccagct ctttggcgag gaagaatccg cccatatcac aagccagtag cgtacccgcg
    54601 aacatggatg ggttcgcgcc cagcatttcg tataccggga taataaccgg ccccagtaca
    54661 tgcgccagca ccggcgccag cgcggtcata ccaaccatcg ccagtcccaa cgcgcccatc
    54721 gccataaagc cctcttcaaa ctggccgcca gacccctcga tactcttgcc aaatttaccg
    54781 aggaagcgcg ccgacccgcc gaactgcgac aggatcctgt ccacggcggc aatcagcata
    54841 aagaacatca tgatgtacat gatgatttcg ttaattccca tagcccctac tccctgtcat
    54901 ttttgatttg taagccggat aagacgttta cgtcgcctcc ggcattaacg ccgtgttatt
    54961 gccggatggc gatgcgagca ccttatccgg cctacagcat tacccggcag ccgcgtacag
    55021 gtcgataatc tgtgcctgtg tggcggtgcg tgggttactg cgcagacaaa tatcctccag
    55081 cgcggcttgc gcccacgcgc tgtagtgttc gggtttggcg ccagcgtcag ccagccgttt
    55141 gctctgcccc acttcggcaa tcagctcgca caccgccgca atcgcatcgc gatcgtccga
    55201 tttcttattg gttaacgccc gaccgatttg actgaagcgc tcgcggcata ccatccggtt
    55261 aaagcccatg actgtcggca gcagcatggc gttggcctgg ccgtgcggaa tatgcagcgc
    55321 cgcccctggc tggtgcgcca tcgcatgaca cagccccaga ccggcgctgg aaaaggccat
    55381 tcccgccata caggaggcca gcaacatatt ttcacgcgcc gccagatcct gcccatagcc
    55441 gacggccttc ggcagcgatt tgccaatcat cgctatcgcg ccaatcgcca ggctgtcggt
    55501 aaacggcgtg gcgttgagcg cgctgtaggc ctcaatcgca tgcgtcagcg catcgatacc
    55561 ggtcatcgcc gtcacatttg gcggaacgcc ttcggtcacg gcagcatcaa gaatcgccac
    55621 atccggcatt agtgacgcgt gtgccagcac ctgcttgcgc ccgctgaccg cgtcgataat
    55681 caccgtcacg ttggtggttt ctgaaccggt tccggcggtg gtcggcaccg caatcagcgg
    55741 cagacgcggg cgtaatgtac tgcgctcggt catggcgctc agcgtctggt cagggttagt
    55801 caccagcagg gcgaccgctt tcgccgcgtc caacaccgaa ccgccgccaa aggccactac
    55861 gccgtcgcac gccgcctcac gcagttgcgc caccgccgcg cagacatcgg tgatgcacgg
    55921 ctcgcctggc ggacacggcc agaccgtcat cgccacgcct ttcatcgcca ggctgcgtgc
    55981 cagcggcgcg gtcattcccg cctgatgcag gaagctgtcg accatcacaa acaaatggct
    56041 tacgccccgc gcttgcgctt cctgcccgca ggcgccgagc gccccaagcc cgcacagcgt
    56101 gaccggcggt acgctgaacg ttttcacccg ttgcagattc agggtgttga atgcctgaaa
    56161 cagcgccgtc tgtagttcag cttgcataga gtccctccgc tttcgctctc ccgctgttag
    56221 ctatcgccag cggggtcata aacaggctgt gctgcggtaa atgcacctgt aactccggga
    56281 aacgctggcg aaataacgcc tccacgcccg gctgcataca ggaaccgccc gccagccata
    56341 aatcagcaat tccttgccct tcaatgtggc gagcaacgat ctccgccatc ttttcgtaca
    56401 ccggcttcac taccggccaa atctcctgcg cattgctgcg cttgtactgt tccgcctctt
    56461 ctaggggaat acggcggttg cccgccagcg tcagggagat atggtgcccg ccagtggctt
    56521 catcggcgga gtaagtcacc ttgccctgtt tgacgatggc aatgccggta gtgccgccgc
    56581 caatatccac cacgcctgca ttatcaagcg ccagcagatc cgccaccgcc gtcggttcat
    56641 ccagtacgtg gctgacttct aacccagcag actccagcac gttgatcgaa atacgcgggt
    56701 cggtgcccgg tgggaacgag gtcgccgcgt gggtaaagcg gcagccgagc tgctgttcaa
    56761 gggtgtcgag atggcggcgc acgagggtga cggcgccgaa gaaatcccag acgatgccgt
    56821 cacgcacaac gtcggcccag tcaaggcaca ccgccaccgg ctgggcgttg ccgtcgacca
    56881 ccatcgacac cacgtcgcag gtgcccaaat cgacgcccag ccacagcggt gtgtcgctgg
    56941 cggcgggcgt ctggttacac agggccgccg ctttttgcag tcttggggtg agccagagtt
    57001 gttcgtcgtg cgccatgagt catcccttat acaatgcgaa acgcatccac cagcacgcat
    57061 cgacgcagcc gcacaaaggt acgcgcgctg gtcacccctt cgccggttgg cgtagtgata
    57121 gtcatggtgg tccagccttc tccgcccaat ccaagcccgg caatgcacgg cccgtttttg
    57181 acgaaaatgc tggtgtcgat ggcgttcgcc atctggttca tgttgtcgat attgcgcgag
    57241 tgcatcgccg ccgtatggtg gcaaccgcct tcaagttgta ccgccagggc gatggcatct
    57301 tcgacgttgg cgacccgcac caccggcagt accggcatca tcatttcagt gacggcaaac
    57361 ggatggttag ctggcgtttc cacaaatagc aggcgcgttt gatccgggac gttcaggcca
    57421 atggctgcgg cgattttgcc cgcgtcacga ccgacccagt cacggctgac ggtgcctttg
    57481 ccgcgctcat caatattctt cagcagcacc ggctggagct gttcggcctg agcggcagtc
    57541 agtttcaccg cgtgctgacc ttccatcaga cgcatcagct cgtcggcgac gctatccacc
    57601 acaatcagca ctttttcgtc ggcacagatg atgttgttat caaacgacgc gcctttgacg
    57661 atggattgtg cggcgcgcgg caggtcggcg gtctcatcca ccaccaccgg gggattgccg
    57721 gcaccggcgg cgatcaggcg tttattagta tgtttgcgcg ccgcgtccac caccgcttcg
    57781 ccgccggtca ccaccagcag gccaataccg gggtacttga acagccgctg ggcggtttcg
    57841 atatccgggt tcgccacggt gaccagcaga ttttccgggc cgccggcggc gaccaccgcc
    57901 tgattgagga gggtgattgc ccgctgagag acctttttcg ccgccggatg cggggcaaac
    57961 acgacgctgt tgcctgcggc aatcaggctg atggcgttat tgatcaccgt cgccgccgga
    58021 ttggtggacg gcgtgaccga ggccaccacg ccccacggcg cattttcaat caatgtcagg
    58081 ccgttatcgc cggtcagcac ctgcggagat aaacactcga cgcccggcgt gccgcgcgcc
    58141 tgcgccacgt ttttggcaaa tttatcgtca acgcgtccca tgccggtttc gctgacggca
    58201 agttccgcta attctcgggc gtgtttttcg cccgcctcgc gaatggcatg aatggcaagc
    58261 tggcgcatcg ccacgctctt cagcccctgc tgggcccgtt ttgctgccgc cacttcgtca
    58321 tccagggagg caaaaacgcc catctcatga acagtgctgg ccggctggct gctgtctttc
    58381 attttcagca gcaccgcttt caccacctgt tcaatatcct gttgattcat gatgttcagt
    58441 cctatttatg gaaaaccact ttcccgccag ccaccacttc atcgacgatg ccaatgacgc
    58501 acagatcgac cggtgataat tcgctgcgat gcgcctggcg cgcggaactg ccgctgacca
    58561 gcagtaccca ctctccggtt cccgccccga tactgtcgat agcgacggca cactgcccgt
    58621 cggggttgcc ctgggcatcg atcatttcca ccatcagcaa tttgtcatgc gccagtccct
    58681 gatggcggac ggtacatacg atttgtcctg tgacgactgc cagtttcata tccgcctcca
    58741 tggattgccc gttgggtcgt aggccttgaa tctgcgcact atcaggcaat ggcgcgcatt
    58801 catgccggat ggcgacgctg cgcgtcttat ccggcctacc atcaaatgtt gctgcgcctt
    58861 tgaagctgat cgggaacact tcttccagat cgccgtgcgg gcgtggaatc acgtgtacag
    58921 agaccagctc gccaatgcgc tgcgccgcag cggcgccagc atcggttgcg gctttgcacg
    58981 ccgccacgtc gccacgcacc atggccgtac acaggccacc gccaatctgc ttcacaccga
    59041 ccagcttcac gcgtgcggct tttaccatcg catctgaggc ctcaatcagc gcaactaggc
    59101 cccgggtttc aatcattcct aatgcttcca tcgtgttttc ctctcattaa aggggtccag
    59161 aacgggaccg ttcattcaac cagtgtgtgt aagctgcgtt cgcggctcac gtcagcctgg
    59221 cgcggcacgg ctgccaccaa cgccagttcg ataatttcct gcacgctaca gcctcgggag
    59281 aggtcgtgaa gcggcgcggc aagcccctga attagcggcc caacagcgcg atagcctccc
    59341 agacgctgag cgattttgta gccaatattg cccgcctcca gcgacgggaa aatcatcacg
    59401 ttggcgcggc cttgcagcgg gctgtcaggc gctttttgcg cggcgacctc cggtacgaaa
    59461 gcggcgtcaa actgcaattc accgtccaca agcagttgcg gcgcacgttc gcgaacgaac
    59521 tctgtcgcct gctgcacgtt ggcaacattg gggtgacggg cgctgccgtt gcttgaaaat
    59581 gacagcatcg ccacgcgcgg ctcttcgccg gtaatggccc gccaggtgtc ggcgctggcg
    59641 atagcgatat ccgccagctg cgccgccgtc ggctgcggca ctacgctgca atcggcgaac
    59701 cctaatgccg ggccggcata ctgcggcagc atcaggaaaa tagacgataa tgttttgcac
    59761 ccgggttgca ggccaatcac ccgcagccct gcgcgcagca cgttcgccgt tgacgacagg
    59821 ttgcctgcga tacacacatc agcctcaccg gcgctcacca tggcggcagc gaacattagc
    59881 gggtcgctaa gcttttccac tgcgtccggc ggcgtttttt ctccggcacg ggcaagccag
    59941 cgttgcgcaa aacgctggcg catactcagg ttgctgtgtg ggtcgatgac ctgaatgcca
    60001 tccatcgcca tacgatgact cagggcaaac tgacgcagcg caaacggact ggcgaccaga
    60061 acggggcgag ccagaccgca ctgttgcagg taatgcgccg ctttcagcac gcgttcgtcc
    60121 agcgcatcgg gaaagacgac tctggcgggg gcgcgtaccg ccagttcgcg ggcgcgttca
    60181 atgatcatgg cttctctccc aaccgttgtt gaatttgggc gaccgtcagc ggatgtttcg
    60241 ccacgctcaa aatcatcatc acgtaaaccg tgctggagag acggtttagc gcctgtaaaa
    60301 tgtccgggcg caagacctca aaactacggg taataaacac ttgtgcggcg agggtttccg
    60361 tttcgcggac tttggttcgc agcagattaa gcagcgccgc atcgcgaccg tggctggcct
    60421 ccggcaccag gtgatcgtgg tcgagatagc gcagcggctg gtgggaaagc cgatgcagct
    60481 catcctcgtt cagcccgacg atagactgcg ccgccagcgg ttcatctata gcgtcggcgc
    60541 gcataatgtt gcccagccgc gagcggatat cgaaaagcca cggctgccag ggttccgcca
    60601 gttcgatttg tagccacacg gtcagcgcga tggcgctgtc gagcgcggcg cgaaagccga
    60661 ggcgcgggtc gcttttggcg accattttgt ccgccgtcag atgggtcagc gtatcgggct
    60721 ttttcaccac cggctggcgg cacagttcac agcaggcctg tgggtgcgta tcgctactgg
    60781 ttaagccatg taccggctgc tgttcgtcat catcgacaaa cagccggcct tgctgatcca
    60841 gaaacttaat gcgcaggcga cgactttcca gcagttcccg ggccgagggc gtcagtcgtg
    60901 cgtcagcggg cagatggatt tccgatcctt cgctgagcgt atgattcgct ctgagccacg
    60961 tttcggtgat gaaatcgttc atacggattg ccagtttgca ggccaggcga cgtacagaaa
    61021 gcgcacggac gttggcgtgc caaattcaat gctggagcct ttagggatga acatgacatc
    61081 tccggctttg gcaatcatgg tttcgccttc atggcgtacg tgcagttcac cctccagcac
    61141 catgtcgatt tcgtcgtagt tcagcgtcca cgggaaaaag gcgttgtccc actgcataaa
    61201 cccggcggcc atgctgctgc catcctgctc tgtaaccaga tcggttaagc cgacgcagtg
    61261 cggttcggcg ccgtcgaagc ggccaaattt cacgctgctg ccgtcaatga ctttcacgcc
    61321 gcctttaccc gtgacggagg taaagctcgg ctgcatcgtc cccagttcca gcgactgctt
    61381 ttccttgagc actttttcca tcaactgcgc caccaggctt tcagtaaact gcccttccgg
    61441 gcgctgcgcg atgatggctt cccgaatgcg ctggctttcg cttttacacg cctgcgccga
    61501 tgtggatgcc gggacggact cgtcgcattc ggtaatcgtg aagcccagta gttccgccac
    61561 ttcgcgagcc tccggggtaa taatgctggc gcgcagcact accgacatcg cctgttcgcc
    61621 gcgggcgtgg gccgcacgaa tatcgttagc tgtgataagt tttttcacct gcctcttcct
    61681 cctgttcact gagagccgcc agataatcca ccaactgccg cacgctttgc gggtcgtggc
    61741 cgttgagctc gaaaatcggc tcccggaatc caatctcgca aagcaactgc cgcgtagcgg
    61801 cgacgtcggc atccggcatg tccgttttgc tgataacggc gatatgtcgt ttacgggttc
    61861 caacatccaa taacccggca ggtaagcgac tttctttatc gtttgccgcg tggacataaa
    61921 tcagcgtgtc cacatcctgc aacgtggtaa ttaaggcgtg ataccaacgg ggatggctaa
    61981 aatattcacc cggcgtatcg atatcgccat gatcattaaa ttccacggcc tgcgtttttc
    62041 tggcgaggga ataatttccc cgtaacgcgt taaaaagcgt tgtctttccg gcgccgaccg
    62101 cgccgacaaa agcaatacgt ttcattaccg ccaccaatta actttttgtt aactcacaca
    62161 gggtgaagtt taataatcgc cccagcccgc tgaccgtctg taatagcgct tcttctactg
    62221 cgccgacggt gccataaatc accagcgcgc cgctaaatct gtcgagaaaa ccgatgtgta
    62281 catccgcagc cttcatcgct aaatcgccag cgatcatggc cgtttccccc ggcgttaagg
    62341 tcataatgcc aatcgcgcca gcatcgggaa cgccgatctt tttcgccagt tcttcaccag
    62401 ggtgcgcaat gagatgcgcc agcgtgacct gtttgcccgg cacaaattcc tgaataatgc
    62461 gttctttatt cattgctcac cgtctccact gaaactgccg tcatcgtggc aattttttgt
    62521 cggagtaaat aacaaaattc ggcaaggtga tgtaaaaggt gaggtagatc actaagagaa
    62581 agaaaataaa agggacttct gtcgaaggtg ttaacga
//
LOCUS       DAJVKX010000005        62050 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000005 DAJVKX010000000
VERSION     DAJVKX010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 62050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62050
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.005"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            182..2572
                     /locus_tag="OPY25_000308"
     CDS             182..2572
                     /locus_tag="OPY25_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone-dependent
                     dehydrogenase"
                     /protein_id="HCS0926026.1"
                     /translation="MAENNARSPRLLVTLTALFAALCGLYLLIGGVWLVAIGGSWYYP
                     IAGLVMLVVAGLLWRSKRAALWLYAALLLATMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWHRLVVPSSGAVAALVVALLISGGILTWAGFNDPQEINGTLRADATPAATS
                     SSIADEDWPAYGRNQEGQRYSPLKQITADNVHQLKEAWVFRTGDLKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHFDPQLKTDSSFQHVTCRGVSYHEAKAD
                     TASPEVIADCPSRIILPVNDGRLFAVNAETGKLCETFANKGVLNLQTNMPDTTPGLYE
                     PTSPPIITDKTIVIAGSVTDNFSTRETSGVIRGFDVNSGKLLWAFDPGAKDPNTIPAD
                     EHAFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVDGTTVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVAKTQPFSDLTFRPKKDLSGADMWGATMFDQLVCRVMFHQL
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPDRQVAIANPMALPFVSKLIPRGPGN
                     PMEPPKDAKGTGTEAGIQPQYGVPFGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEI
                     VWKKRIGTPRDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDAK"
     gene            complement(2650..4260)
                     /gene="cueO"
                     /locus_tag="OPY25_000309"
     CDS             complement(2650..4260)
                     /gene="cueO"
                     /locus_tag="OPY25_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HCS0926027.1"
                     /translation="MLRRDFLKYSVALGVASALPLWSRAAFAAERPALPIPDLLTADA
                     SNRMQLIVKAGQSTFAGKNATTWGYNGNLLGPAVQLHKGKSVTVDIHNQLAEDTTLHW
                     HGLEIPGIVDGGPQGIIPAGGTRTVTFTPQQRAATCWIHPHKHGKTGRQVAMGLAGLV
                     LIEDDEIRKLRLPKQWGIDDVPVIIQDKRFSADGQIDYQLDIMTAAVGWFGDTLLTNG
                     AIYPQHSAPKGWLRLRLLNGCNARSLNIAASDNRPLYVIASDGGLLAEPVKVTELPLL
                     MGERFEVLVDISDGKAFDLVTLPVSQMGMAIAPFDKPHPVMRIQPLRITASGTLPDTL
                     TTMPALPSLEGLTVRNLKLSMDPRLDMMGMQMLMKKYGAQAMSGMDHDSMNAHMQGGN
                     MGHGEMDHGNMDHSGMNHGAMGNMNHGGKFDFHNANFINGQVFDMNKPMFAAQKGRHE
                     RWVISGVGDMMLHPFHIHGTQFRILSENGKAPAAHRTGWKDTVRVEGGISEVLVKFDH
                     DAPKEHAYMAHCHLLEHEDTGMMLGFTV"
     gene            4462..4809
                     /locus_tag="OPY25_000310"
     CDS             4462..4809
                     /locus_tag="OPY25_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HCS0926028.1"
                     /translation="MKTFFRPVLFGSLMALCANSYALTESEAEDMADLTAVFVFLKND
                     CGYQNLPNSQIRRALVFFAQQNQWDLSNYDTFDMKSLGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            4916..5776
                     /gene="speE"
                     /locus_tag="OPY25_000311"
     CDS             4916..5776
                     /gene="speE"
                     /locus_tag="OPY25_000311"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HCS0926029.1"
                     /translation="MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     TITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEALDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSSEIIQARFHAAGLKCRYYNSAIHAAAFALP
                     QYLHDALSAQ"
     gene            5797..6591
                     /gene="speD"
                     /locus_tag="OPY25_000312"
     CDS             5797..6591
                     /gene="speD"
                     /locus_tag="OPY25_000312"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HCS0926030.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPIDPKLIDQTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDVNGMKHFIDHEINSIQNFMSEDMKSLYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTETERQQITAALWKEMREIYYGRNISAV"
     gene            complement(6621..7388)
                     /locus_tag="OPY25_000313"
     CDS             complement(6621..7388)
                     /locus_tag="OPY25_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0926031.1"
                     /translation="MKGQHRLDLIVAYLKNHTLVTVEQLVEAVDASPATIRRDLIKLD
                     EQGVISRSHGGVALRRFEPAQPTTNEKQLRSPAEKRAIARVAASLVNAGDAVVLDAGT
                     TMMELAKCLTHLPLRVITVDLHIALFLAEFRQIEVTIVGGRIDDSSQSCIGEHGRKLL
                     RSVYPNIAFMSCNSWGVKTGVTTPTEDKAGLKQEIIANAQRKVLLADSSKYGAHSLFN
                     VVPLERFNDVITDVNLPPSAQVELKGRAFALTLVQPE"
     gene            complement(7398..8381)
                     /locus_tag="OPY25_000314"
     CDS             complement(7398..8381)
                     /locus_tag="OPY25_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-threonate 4-phosphate dehydrogenase"
                     /protein_id="HCS0926032.1"
                     /translation="METKTVAITMGDPAGIGPEIIVKALSEDGLNGAPLVVIGCLATL
                     KCLQAKGITPNVELRAIERVAEARFAPGIIHVIDEPLAQPEALEAGKVQAQAGDLAYR
                     CVKRATELALRGDVQAIATAPLNKEALHLAGHNYPGHTELLATLTHSRDYAMVLYTDK
                     LKVIHVSTHIALRKFLDTLSTTRVETVIGIADTFLKRVGYVKPRIAVAGVNPHAGENG
                     LFGDEETRILTPAITDARAKGMDVYGPCPPDTVFLQAYEGQYDMVVAMYHDQGHIPLK
                     LLGFYDGVNITAGLPFIRTSADHGTAFDIAWTGKAKSESMAVSIKLAMQLA"
     gene            complement(8371..9642)
                     /locus_tag="OPY25_000315"
     CDS             complement(8371..9642)
                     /locus_tag="OPY25_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-threonate kinase"
                     /protein_id="HCS0926033.1"
                     /translation="MKMMVIADDFTGSNDTGVQLAKKGARTEVMLSASQKPSRRADVL
                     VINTESRAMPADQAASAVYAALSPWCETSPAPLVYKKIDSTFRGNIGAEVTAAMRASQ
                     RKLAVIAAAIPAAGRTTLEGKCLVNGAPLLETEFASDPKTPIVSSRIAEIVALQSEIP
                     VYEVFLQDVRRGGLSALLTAYAAEGEGIIVVDAVEERDLTLIAQAACEQPSMPLLVGA
                     AGLANALPVELFMQDRQRLPVLVVAGSMSEATRRQVDNALCRGRAEVVDIDAARMVSD
                     SAEQEIASVVEQACALLSQHRHTILRTSRRAEDRQLIDALCEKSAMSRQQLGERLSHR
                     LGVVTLNIIEQARIGGLFLTGGDIATAVAGALGAEGYRIQSEVAPCIPCGTFVNSEID
                     DLPVITKAGGFGSDSTLCDALYYIEEMYCGD"
     gene            complement(9639..10592)
                     /locus_tag="OPY25_000316"
     CDS             complement(9639..10592)
                     /locus_tag="OPY25_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease 1"
                     /protein_id="HCS0926034.1"
                     /translation="MNIKKAIERVPGGMMVVPLVIGAVINTFAPQALEIGGFTTALFK
                     NGAAPLIGAFLLCMGAGISVKAAPQALLQGGTITLTKLLVAIGIGLGVEHLFGAEGIF
                     GLSGVAIIAAMSNSNGGLYAALVGEFGNERDVGAISILSLNDGPFFTMIALGAAGMAN
                     IPIMALVAVLVPLVVGMILGNLDPHMRDFLTKGGPLLIPFFAFALGAGINLEMLLQGG
                     LAGILLGVLTTFVGGFFNIRADRLVGGTGIAGAAASSTAGNAVATPLAIAQADPSLAE
                     VAAAAAPLIAASVITTAILTPVLTSWVAKKQARQASLEKNA"
     gene            complement(10827..11189)
                     /locus_tag="OPY25_000317"
     CDS             complement(10827..11189)
                     /locus_tag="OPY25_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HCS0926035.1"
                     /translation="MDYEFLRDVTGRVLVRMSMGHEVVGHWFNEEVKDNLSLLDEVEQ
                     AARTVKGSERSWQRAGHEYTIWMDGEEVMIRANQLDFSGDEMEEGMSYYDEESLSLCG
                     MEDFLRVVAAYREFVSKA"
     gene            complement(11377..13974)
                     /gene="acnB"
                     /locus_tag="OPY25_000318"
     CDS             complement(11377..13974)
                     /gene="acnB"
                     /locus_tag="OPY25_000318"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HCS0926036.1"
                     /translation="MLEEYRKHVAERAAQGIVPKPLDATQMAALVELLKTPPVGEEEF
                     LLDLLINRVPPGVDEAAYVKAGFLAAVAKGDTTSPLVSPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLSRP
                     PLAEKITVTVFKVTGETNTDDLSPAPDAWSRPDIPLHAQAMLKNAREGIEPDQPGVVG
                     PIKQIEALQKKGYPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPNVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETDELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESSRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVTTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIVEYLTSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLADPQLLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARLLSDVQGEKIDEVFIGSCMTNIGHFRAAGKLLDSHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTFVAQVDKTAVDTYRYLNFDQLSQYTEKA
                     DGVIFQTAV"
     gene            14363..15985
                     /locus_tag="OPY25_000319"
     CDS             14363..15985
                     /locus_tag="OPY25_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HCS0926037.1"
                     /translation="MTLPFKPHLIALVCSAGLFAASGVLYVKSRAPEAPAQAAAPTSE
                     PTQTAVPAPVAKTTFTTAQIDQWVAPVALYPDALLSQVLMASTYPANVVQAVQWSRDN
                     PTLQGDAAIQAVASQPWDPSVKSLVAFPQLMALMGENPQWVQNLGDAFLAQPQDVMDA
                     VQRLRLLAQQTGSLKSTPQQTVTSVPKSSASTAVTTTTTTSASTPATPSTVIKIEPAN
                     PQVVYVPNYNPTTVYGAWPNTAYPPVYLPPPPGQQFADSFVKGFGYSLGVATTYALFS
                     SIDWDDDDHHHHDDDHHDDDYHHGGNGYQHNGNNININVNNFNRISGQNLPGQTMGWQ
                     HNPAWRNGVPYPNNTVAQRFHPTNVSGGLSATQQAPVSRDSQRQAAMAQFQQRSHTSP
                     ANVSGETSRDRQRKAASQQLNQIAQRNNYRGYDGTQNSSRREAAQQTLNKSTTQQHRS
                     ELKAKAQQHPVSQQQRDTARQRIESSTPQQRQAFRQNMHANVFSGNDSRSPSWQSQQL
                     RGLESRRGSHLNTEQRAAAREHFSEHHEFHRR"
     gene            15998..16789
                     /locus_tag="OPY25_000320"
     CDS             15998..16789
                     /locus_tag="OPY25_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2950 family protein"
                     /protein_id="HCS0926038.1"
                     /translation="MKKVMLSALLLSLPLLGYAQERFPSPEAAASAFAAAVAGKNETQ
                     LTALLGDDWRQFLPPEGADPEAVARFNRDWREGHRIVQKDNTAHLNVGREDWQLPVPM
                     VKETGGWRFDMAAAGNEILTRTIGRNELSTLQAMHAYVDAQQDYYLQNHRWAHRIISS
                     EGQKDGLYWPTKAGDVPSPLGPNFSPAAPDEGYHGYHFRIISDNDGHGAALLAWPMHY
                     GETGVMSFMVNQDDRIYQADLGKETESKVQAITRFAPDAQWQVAE"
     gene            complement(16827..17111)
                     /locus_tag="OPY25_000321"
     CDS             complement(16827..17111)
                     /locus_tag="OPY25_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein"
                     /protein_id="HCS0926039.1"
                     /translation="MKLFLTTAALTATLISGMAFASDPVIPWATNSGGTESTHIAAMG
                     EDLNAQHQQITHTHEGVWAANSGSIQADEAALTSNKPPVQGHPELMPHQG"
     gene            complement(17400..18824)
                     /gene="lpdA"
                     /locus_tag="OPY25_000322"
     CDS             complement(17400..18824)
                     /gene="lpdA"
                     /locus_tag="OPY25_000322"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCS0926040.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVITQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RVWDSTDALELKEVPKRMLVMGGGIIGLEMGTVYHALGSEIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVSMEGKKAPAEAQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEIFEGSITDLPNPKAKKK"
     gene            complement(19026..20915)
                     /gene="aceF"
                     /locus_tag="OPY25_000323"
     CDS             complement(19026..20915)
                     /gene="aceF"
                     /locus_tag="OPY25_000323"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459158.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCS0926041.1"
                     /translation="MAIEIKVPDIGTDEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGVVKEIKVSVGDKTETGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVHVPDIGSDEVEVTEVMVKVGDTVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNTGDKVSTGSLIMVFEVAGEAGAAAPAKAEAAPAAAAPAAATGVKDVNVPDIGGDE
                     VEVTEVMVKVGDKVTAEQSLITVEGDKASMEVPAPFAGTVKEIKISTGDKVKTGSLIM
                     VFEVEGAAPAAAPAKQEAAAPAPAAKAEKPAAPAAKAEGKSEFAENDAYVHATPLIRR
                     LAREFGVNLAKVKGTGRKGRILREDVQAYVKDAIKRAEAAPAAAGGGIPGMLPWPKVD
                     FSKFGEVEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITDLEAFRKQQNAEAEKR
                     KLDVKYTPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVVP
                     VFKDVNKKSVTELSRELTTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVNA
                     PEVAILGVSKSAMEPVWNGKEFVPRLMMPISLSFDHRVIDGADGARFITIINNMLSDI
                     RRLVM"
     gene            complement(20930..23593)
                     /gene="aceE"
                     /locus_tag="OPY25_000324"
     CDS             complement(20930..23593)
                     /gene="aceE"
                     /locus_tag="OPY25_000324"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HCS0926042.1"
                     /translation="MSERFQNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEA
                     RKGGVKVAAGAGASNYINTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGIYARAFLEGRLTQ
                     EQMDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIV
                     NELEGIFAGAGWNVIKVMWGGRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKVYAALKKAQETKGKATVILAHTI
                     KGYGMGDTAEGKNIAHQVKKMNMDGVRYVRDRFNVPVADADLEKLPYITFPEGSEEHK
                     YLHERRQALHGYLPSRQPNFTEKLELPQLSDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGASWLAAATSYSTNDLPMIPFYIYYSMFGFQRIGDLCWQAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETLEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAITKFNIDADKVNPRLA"
     gene            complement(23753..24517)
                     /gene="pdhR"
                     /locus_tag="OPY25_000325"
     CDS             complement(23753..24517)
                     /gene="pdhR"
                     /locus_tag="OPY25_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HCS0926043.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQFDLLE
                     TRHALEGIAAYYAALRSTDEDKDRIRELHHAIELAQESGDLDAESEAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYARREMLPLVSTHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEIMLDRSREESRRERALRRLEQRKN"
     gene            25080..26453
                     /gene="aroP"
                     /locus_tag="OPY25_000326"
     CDS             25080..26453
                     /gene="aroP"
                     /locus_tag="OPY25_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HCS0926044.1"
                     /translation="MMDSQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGGFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWASAAAFFVIINAINLTNVKVFGEMEFWFAIIK
                     VIAVIAMILFGAWLLFSDTAGPQATVRNLWEQGGFLPHGWTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLLPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALLNVDKRGVPV
                     SSILVSAVVTALCVLLNYLAPESAFGLLMALVVSALVINWAMISLAHMMFRRAKQQQG
                     VKTRFPALFYPFGNVLCLLFMAAVLIIMLMTPGMAISVWLIPVWLLILGVGYLCKEKT
                     AKTVKAH"
     gene            26617..28023
                     /locus_tag="OPY25_000327"
     CDS             26617..28023
                     /locus_tag="OPY25_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0926045.1"
                     /translation="MDKGRLSVREKIGYGMGDAGYNIIFGAIMLFVNYFYTDIFGLAP
                     ALVGVLLLSVRVIDAVTDPVMGALADRTQSKYGRFRPWLLWIAFPYALFSVLMFTTPD
                     WGYNSKVIYAFVTYFLLSVTYTAINIPYCSLGGVITNDPKERVACQAYRFVLVGIATL
                     LLSLTLLPMVDWFGDGDKAKGYQLAMTVLAIIGMGMFLFCFASVRERVRPAVPTHDDM
                     KNDFKDVWKNDQWVRILLLTLCNVCPGFIRMAATMYYVTWVMGQSTHFATLFISLGVV
                     GMMIGSMLAKVLTDRWCKLKVFFWTNIALAIFSCAFYFFDPKATVMIVALYFLLNILH
                     QIPSPLHWSLMADVDDYGEWKTGKRITGISFSGNLFFLKLGLAIAGAMVGFLLSWYGY
                     DASAKAQSASAMNGIMLLFTVIPGVGYLITAGVVRLLKVDRELMKKIQDDLEKRRTNY
                     RELSELQELKAAESVRKA"
     gene            28023..28973
                     /locus_tag="OPY25_000328"
     CDS             28023..28973
                     /locus_tag="OPY25_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HCS0926046.1"
                     /translation="MANWPNPFIEQRADPFILRDGSDYYFIASVPEYDRLEIRRADSL
                     EGLRAADPVVVWRKPESGPMSQLIWAPEMHRINGKWYIYFAATHTQALDKLGMFQHRM
                     FALECADADPLTGKWTEKGQIKTPFDTFSLDATTFYHQGKQWYLWAQKAPDIAGNSNI
                     YLAELENPWTLKGEPVRLSKPEYDWECRGFWVNEGPAVVVHGDKLFISYSASATDENY
                     CMGLLWINVNDDPRDPANWHKSPRPVFTTSYENRQYGPGHNSFTQTSEGEDVLVYHAR
                     NYTEIEGDPLYDPNRHTRLKRVRWDENGMPDFGVPPADTI"
     gene            complement(29065..29919)
                     /gene="ampE"
                     /locus_tag="OPY25_000329"
     CDS             complement(29065..29919)
                     /gene="ampE"
                     /locus_tag="OPY25_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HCS0926047.1"
                     /translation="MTLFTTLLVLIVERLFKLGEHWQLDHRLEALFRRITHFSMLRTM
                     GMTAIAMVVTFLLLQALKGLLFNVPTLVVWILLGVLCIGAGKVRVHYHAWLKAASRND
                     PHPCEAMASELTLIHGVPPDCNEREFLRELQNALLWINFRFYLAPLFWFIVGGPWGPV
                     TLVGYAFLRAWQTWLARYQTPHQRLQSGIDAILHVLDWIPVRLAGVVYALLGHGEKAL
                     PAWFASLADLHTSQYQVLTRLAQFSLVREPHTDKVETPKAAVSMAKKASFVVVVIIAL
                     LTIYGALV"
     gene            complement(29916..30479)
                     /gene="ampD"
                     /locus_tag="OPY25_000330"
     CDS             complement(29916..30479)
                     /gene="ampD"
                     /locus_tag="OPY25_000330"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HCS0926048.1"
                     /translation="MLPDKGWLVEARRVPSPHYDCRPDDEKPSLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPDAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSNY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRTLIACYPAIADNMTGHCNIAPD
                     RKTDPGPAFDWPRFRALVALSSHKEMT"
     gene            30567..31460
                     /gene="nadC"
                     /locus_tag="OPY25_000331"
     CDS             30567..31460
                     /gene="nadC"
                     /locus_tag="OPY25_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HCS0926049.1"
                     /translation="MPPRRYNPDDRRDALLERINLDIPAAVAQALREDLGGEVDAGND
                     ITAQLLPADTQAHATVITREDGVFCGKRWVEEVFIQLAGDDVRLTWHVDDGDAIHANQ
                     TVFELNGPARVLLTGERTALNFVQTLSGVASEVRRYVGLLAGTQTQLLDTRKTLPGLR
                     TALKYAVLCGGGANHRLGLTDAFLIKENHIIASGSVRQAVEKAFWLHPDVPVEVEVEN
                     LDELDDALKAGADIIMLDNFNTDQMREAVKHVNGQARLEVSGNVTAETLREFAETGVD
                     FISVGALTKHVRALDLSMRFC"
     gene            31682..32119
                     /gene="ppdD"
                     /locus_tag="OPY25_000332"
     CDS             31682..32119
                     /gene="ppdD"
                     /locus_tag="OPY25_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HCS0926050.1"
                     /translation="MEKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGTSTCDAGVNGIPSPVITRYVSGMSVEKGVITLTGQESLSG
                     LSVIMTPAWDNANGITGWTRNCNIQSDSALQQACEDVFRFDAN"
     gene            32129..33514
                     /gene="gspE"
                     /locus_tag="OPY25_000333"
     CDS             32129..33514
                     /gene="gspE"
                     /locus_tag="OPY25_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HCS0926051.1"
                     /translation="MKDAQLNTLCQRHQAVLINSASNSITVAVVDAPSHALLDALHFA
                     TQKQIDIVCWTRQQMENHRHKPDQAPSTNAAKGGETAAQLLNQTLRSAMAKRASDIHL
                     EPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDL
                     TGDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLV
                     LVTGPTGSGKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNV
                     LRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQIGVT
                     RWMISSALTLVVAQRLVRKLCPHCKQRLSDPVVLSPNLWPSALPRWQANGCQHCYHGF
                     YGRTALFEVLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEE
                     ILRVLGMPHER"
     gene            33504..34706
                     /gene="hofC"
                     /locus_tag="OPY25_000334"
     CDS             33504..34706
                     /gene="hofC"
                     /locus_tag="OPY25_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HCS0926052.1"
                     /translation="MSVKQLWRWQGVNDKGQLEQDVVWVDNRLALIITLQHQRIMPLR
                     IKRISVNAALWKEEQSAEIIHQLATLIHAGLTLSEGLELLAKQHPHRQWQALLRTLAH
                     ELEQGVPFSSALVSWPQVFPPLYQTMIRTGELTGKLAECCFELARQQKAQRQITVSVK
                     KALRYPAIILTMAALVVFAMLHFVLPEFAAIYRSFNTPLPLLTRGIIAIAQWGPAWGW
                     LILFLTMLVAIAHRRLKQKPSWQAQRQRLLLRLPVMGRLIRGQKLAQIFTVLALTQSA
                     GIPFLQGLESAIDSLGCPYWSQRLTQVHQEIAAGNPVWLALKNTQEFSPLCLQLVRTG
                     EASGSLDIMLHNLARHHSESTLALADNLASLLEPALLIITGLIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(34737..35780)
                     /locus_tag="OPY25_000335"
     CDS             complement(34737..35780)
                     /locus_tag="OPY25_000335"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCS0926053.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTW
                     SGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYSVEEWAAFINTASADVLKHVMVS
                     TGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPSKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMN
                     RHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNSL"
     gene            36006..36626
                     /gene="coaE"
                     /locus_tag="OPY25_000336"
     CDS             36006..36626
                     /gene="coaE"
                     /locus_tag="OPY25_000336"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCS0926054.1"
                     /translation="MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQ
                     PALNAIAEHFGSELIAADGTLRRRALRERIFSHPEEKAWLNALLHPLIQQETQRQFQQ
                     ATSPYVLWVVPLLVENRLYQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHASYLKLASQFVSQEKP"
     gene            36626..37369
                     /gene="zapD"
                     /locus_tag="OPY25_000337"
     CDS             36626..37369
                     /gene="zapD"
                     /locus_tag="OPY25_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HCS0926055.1"
                     /translation="MHTQVLFEHPLNEKMRTWLRIEFLIQQLSINLPIADHAGALHFF
                     RNISDLLDVFERGEVRTELLKELERQQRKLQAWVEVPGVDQDRIEALRQQLKSAGSVL
                     ISAPRIGQQLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLQQAQRDAQIESWLAS
                     LNPLTQALTLVLDLIRNSAPFRKQTSLNGFYQDNGDDADLLRLMLTLDSQLYPQISGH
                     KSRFAIRFMPLDSENGLVPERLDFELACC"
     gene            37379..37570
                     /gene="yacG"
                     /locus_tag="OPY25_000338"
     CDS             37379..37570
                     /gene="yacG"
                     /locus_tag="OPY25_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HCS0926056.1"
                     /translation="MSDVTVVNCPTCGKPVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIASSGDQSDSDDWSEER"
     gene            complement(37567..38508)
                     /locus_tag="OPY25_000339"
     CDS             complement(37567..38508)
                     /locus_tag="OPY25_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001697068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0926057.1"
                     /translation="MKAGLIMRHDVMSVLHAFCMIAENHSFTRAAAQLHISTSALSQN
                     MRQLEDELGVKLLNRTTRRVGLTEAGHAFLASIRPALNHIDEAMEHACQSRDIPGGTL
                     RLTVPRTAATLLLQPNLAGFMRDYPDIRLDIDVNDGFVDLINERFDAGIRFGDAVQLD
                     MNVVPLGDVLRPAIVASPAYLARFGTPLHPQELINHRCLCHRFTRESGLYRWEFVHGA
                     QRLEITPEAALMVNDKALRLSAARDGAELTYVFEQDVHEDLQDGRLCSVLEEWLPAAD
                     RFYLYYPGRAHMAPKLRVFIDYFCHKAILPSQQSYHR"
     gene            38594..39583
                     /locus_tag="OPY25_000340"
     CDS             38594..39583
                     /locus_tag="OPY25_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCS0926058.1"
                     /translation="MQYRTLGANGPRVSAIGLGCMGMSAFYGAHDDSTSIKTLHYALD
                     QGVTLLDTADMYGPYTNERLVGRAIADRRDRVFLATKFGIVLDPANPMARGVNGRPEY
                     VRRSCEQSLQRLGVDHIDLYYQHRVDPSVPIEETVGAMADLVREGKVRYLGLSEASTQ
                     TLERAHNVHPITALQSEYSLWSREAEISALSTCERLGIGFVAYSPLGRGFLTGTIKTP
                     EDFAANDFRRTNPRFMGENFSRNLRLAEAIKQMAREKECTPAQLALAWLLARNRHLVP
                     IPGTRHCARVDENLGALSLTLSPQELAAIEAVFPHDAAAGPRYWPEIMSTLNR"
     gene            complement(39617..40012)
                     /gene="mutT"
                     /locus_tag="OPY25_000341"
     CDS             complement(39617..40012)
                     /gene="mutT"
                     /locus_tag="OPY25_000341"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HCS0926059.1"
                     /translation="MKKLQIAVGIIRNPNDEIFITRRAADAHMANKLEFPGGKIEAGE
                     TPEQALIRELQEEVGITPTQVTLFDTLEYQFPDRHITLWFWLVERWEGEPWGKEGQPG
                     RWIAQNALNTDDFPPANEPIIRKLRQFAP"
     gene            complement(40168..42873)
                     /gene="secA"
                     /locus_tag="OPY25_000342"
     CDS             complement(40168..42873)
                     /gene="secA"
                     /locus_tag="OPY25_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCS0926060.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELK
                     AKTNEFRARIGKGESVESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEM
                     RTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKKVNKIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTE
                     RGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYITEAEKIQAIIEDIKERTANGQ
                     PVLVGTISIEKSEVVSRELTKAGIKHNVLNAKFHANEAGIVAQAGYPAAVTIATNMAG
                     RGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQ
                     LSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRLS"
     gene            complement(42935..43432)
                     /gene="secM"
                     /locus_tag="OPY25_000343"
     CDS             complement(42935..43432)
                     /gene="secM"
                     /locus_tag="OPY25_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308128.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HCS0926061.1"
                     /translation="MSGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPA
                     RTTASTASKVNFSHLALLEASNRRPNFTVDYWHQHAIRTVIRHLSFAMAPQTLPVADA
                     PSPLQAHHIALLNTLSAMLTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAG
                     PQRLS"
     gene            complement(43713..44630)
                     /gene="lpxC"
                     /locus_tag="OPY25_000344"
     CDS             complement(43713..44630)
                     /gene="lpxC"
                     /locus_tag="OPY25_000344"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HCS0926062.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDALNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTID
                     FNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEFVTFQDDAELPLAFKAPSTVLA"
     gene            complement(44731..45882)
                     /gene="ftsZ"
                     /locus_tag="OPY25_000345"
     CDS             complement(44731..45882)
                     /gene="ftsZ"
                     /locus_tag="OPY25_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCS0926063.1"
                     /translation="MFEPMELTNDAVITVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDREALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VLDRYQQHGMAPLTQEQKTVAKVVNDNAPQAAKEPDYLDIPAFLRKQAD"
     gene            complement(45943..47205)
                     /gene="ftsA"
                     /locus_tag="OPY25_000346"
     CDS             complement(45943..47205)
                     /gene="ftsA"
                     /locus_tag="OPY25_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCS0926064.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEQLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            complement(47202..48032)
                     /gene="ftsQ"
                     /locus_tag="OPY25_000347"
     CDS             complement(47202..48032)
                     /gene="ftsQ"
                     /locus_tag="OPY25_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HCS0926065.1"
                     /translation="MSQAALNTRNSDEETPSSRRNNGTRLAGILFLLTVLCTVFVSGW
                     VVLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQAILALGAPGTFMTQDVNIIQSQIER
                     LPWIKQASVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPSDRIGKQVLPML
                     YGPEGSASEVLQGYREMGQVLAKDKFTLKEAAMTARRSWQLTLNNGIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESNQQQNQAQAEQQ
                     "
     gene            complement(48034..48954)
                     /locus_tag="OPY25_000348"
     CDS             complement(48034..48954)
                     /locus_tag="OPY25_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCS0926066.1"
                     /translation="MADKIAVLLGGTSAERDVSLNSGAAVLAGLREGGIDAHPVDPQE
                     VDVAQLKAMGFQKVFIALHGRGGEDGTLQGMLELLGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSEEQKARISALGLPLIVKPSREGSSVGMTKVVEE
                     NALQGALSLAFQHDDEILIEKWLCGPEFTVAIVGEEILPSIRIQPAGTFYDYEAKYLS
                     DETQYFCPAGLEASQEAALQSLVLQAWKALGCTGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            complement(48947..50422)
                     /gene="murC"
                     /locus_tag="OPY25_000349"
     CDS             complement(48947..50422)
                     /gene="murC"
                     /locus_tag="OPY25_000349"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCS0926067.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLTSLGATIFFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYHGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QGMPDLHVTLNAPGRHNALNAAAAVAVATEEGIDDDAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKAGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRYTRTRDLYD
                     DFANVLTQVDALLMLDVYPAGEAPIPGADSRSLCRTIRNRGKIDPILVSDPAQVATML
                     APVLTGNDLILVQGAGNVGKIARYLSEIKLKPQIQEEEQHG"
     gene            complement(50541..51608)
                     /gene="murG"
                     /locus_tag="OPY25_000350"
     CDS             complement(50541..51608)
                     /gene="murG"
                     /locus_tag="OPY25_000350"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCS0926068.1"
                     /translation="MSGQPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTSDR
                     MEADLVPKHGIDIDFIRISGLRGKGVKALLAAPLRIFNAWRQARAIMKRFKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNQWLAKIATTVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQVRLAGRDGPIRVLVVGGSQGARVLNQTMPQVAARLGDTVTIWHQS
                     GKGAQLTVEQAYAGAGQPQHKVTEFIDGMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     IFVPFQHKDRQQYWNALPLENAGAAKIFEQPQFTVEAVADTLAGWSREALLTMAERAR
                     AVSIPDATERVASEVSRVART"
     gene            complement(51605..52849)
                     /gene="ftsW"
                     /locus_tag="OPY25_000351"
     CDS             complement(51605..52849)
                     /gene="ftsW"
                     /locus_tag="OPY25_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HCS0926069.1"
                     /translation="MRLSLPRLRMPRVPGFGFLAWLFAALKGWVMASRDKDADSLIMY
                     DRTLLWLTFGLAAIGFVMVTSASMPVGQRLANDPFLFAKRDALYIFLAFCLAMVTLRL
                     PMTFWQKYSTTMLIASIIMLLIVLVVGSSVNGASRWIALGPLRIQPAEFTKLSLFCYL
                     ANYLVRKVDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVILLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEI
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYIGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     FLLRIDYETRLEKAQAFTRGSR"
     gene            complement(52849..54165)
                     /gene="murD"
                     /locus_tag="OPY25_000352"
     CDS             complement(52849..54165)
                     /gene="murD"
                     /locus_tag="OPY25_000352"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCS0926070.1"
                     /translation="MADYQDKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRVTPPGL
                     DKLPQEVERHVGGLNDEWLLAADLIVASPGIALAHPSLSAAASAGVEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDADRELYVLELS
                     SFQLETTSSLQAAAATVLNVTEDHMDRYPFGLQQYRAAKLRVYEKAKVCVVNADDALT
                     MPVRGADERCVSFGVNMGDYHLNRQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAVGLPRASSLKALTTFTGLAHRFQLALEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLTGDRIRLYCFGRDGAQLAALRPEIAQQTETME
                     EAMRLLAPHVQPGDMVLLSPACASLDQFKNFEQRGDVFTRLAKELG"
     gene            complement(54168..55250)
                     /gene="mraY"
                     /locus_tag="OPY25_000353"
     CDS             complement(54168..55250)
                     /gene="mraY"
                     /locus_tag="OPY25_000353"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCS0926071.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IARLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLIGYGIIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQL
                     VVPFFKDVMPQLGLFYILLSYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAGFALVAWA
                     TGNMNFANYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            complement(55244..56602)
                     /gene="murF"
                     /locus_tag="OPY25_000354"
     CDS             complement(55244..56602)
                     /gene="murF"
                     /locus_tag="OPY25_000354"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCS0926072.1"
                     /translation="MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALK
                     GERFDAHDFADKAKANGAGALLVSRPLDIDLPQVIVKDTRQAFGQLAAWVRMQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTASNFNNDIGVPITLLRLNHDYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMN
                     ADNNDWLNWQSIIGDRQVWRFSPNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLP
                     LPGRHNIANALAAAALSMAVGATLAAVKAGLAALKAVPGRLFPIQLSENQLVLDDAYN
                     ANVGSMTAAVQVLSEMPGYRVLVVGDMAELGAESEACHLQVGEAAKAAGIDRVLSTGK
                     LSQVISHASGVGEHFADKAALIARLHALLQEQPMMTILVKGSRSAAMEDVVHALQEKG
                     SC"
     gene            complement(56599..58086)
                     /gene="murE"
                     /locus_tag="OPY25_000355"
     CDS             complement(56599..58086)
                     /gene="murE"
                     /locus_tag="OPY25_000355"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HCS0926073.1"
                     /translation="MADRNLRDLLAPWVAGLPARELREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEASDGEIREMHGVPVVYLSQLNERLSALAGRFY
                     HEPSENMRLVAVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHVLASLVAQGATFGAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     AHYEAAKWMLYSTHHHGQAIVNADDEVGRRWLASLPDAVAVSMEGHINPNCHGRWLKA
                     EAVEYHDRGVTIRFASSWGEGEIESCLMGAFNVSNLLLALATLLALGYPLTDLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADIVVVTDDNPRTEEPRAIINDILAGMLDAGQVRVMEGRAEAVTN
                     AIMQAKDNDVVLIAGKGHEDYQIVGTQRLDYSDRVTAARLLGVIA"
     gene            complement(58073..59839)
                     /gene="ftsI"
                     /locus_tag="OPY25_000356"
     CDS             complement(58073..59839)
                     /gene="ftsI"
                     /locus_tag="OPY25_000356"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HCS0926074.1"
                     /translation="MKAAAKTQKSKRQEEQTNFISWRFALLCGCILLALVFLLGRAAW
                     LQIIAPDMLVRQGDMRSLRVQEVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALSTALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLAGTPKDAMRNRTITDVFEPGSTVKPMVVMTALQRGIVNENTVLNTVPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERIFPESTVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALATGEKNEFVINQGEGTGGRS"
     gene            complement(59855..60220)
                     /gene="ftsL"
                     /locus_tag="OPY25_000357"
     CDS             complement(59855..60220)
                     /gene="ftsL"
                     /locus_tag="OPY25_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCS0926075.1"
                     /translation="MISRVTEALSKVKGSIGSNERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            complement(60217..61158)
                     /gene="rsmH"
                     /locus_tag="OPY25_000358"
     CDS             complement(60217..61158)
                     /gene="rsmH"
                     /locus_tag="OPY25_000358"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCS0926076.1"
                     /translation="MMENFKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAQTINDPRFSIIHGPFSALADYVAERELTGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTFGEERF
                     AKRIAHAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLSVLASGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGLPMTEAQLKKL
                     GGRELRALGKLMPGEKEVAENPRARSSVLRIAERTNA"
     gene            complement(61160..61618)
                     /gene="mraZ"
                     /locus_tag="OPY25_000359"
     CDS             complement(61160..61618)
                     /gene="mraZ"
                     /locus_tag="OPY25_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCS0926077.1"
                     /translation="MFRGATLVNLDSKGRLTVPTRYREQLIESATGQIVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWYQQVKEDIDAEQSATETLSERLQDLSL"
BASE COUNT        14210 a        17929 c        15849 g        14062 t
ORIGIN      
        1 caaatcactc aatgccggtg actaataacg ccgcattgac gcgcaaggca cgcagtataa
       61 cagcaaacgt attcattcgc ggcatttgat aagaaagctc attttgtgat gacgatcaca
      121 catgttaatt cctatgctta attgctacta aaaaattaac aatttgggat ggtgtctttt
      181 tatggcagaa aataacgcac gatcgccacg attactcgtg acgctgacgg ccctctttgc
      241 agcactttgc gggctgtatc ttcttatcgg aggtgtctgg ctggttgcta ttggcggttc
      301 ctggtactac cccatcgcgg gcctcgtgat gctggttgtg gccggattgc tatggcgcag
      361 taaacgtgcc gcactgtggc tgtatgccgc cctgctgctg gcgacaatga tttggggcgt
      421 gtgggaagtc gggttcgact tctgggcact cacgccgcgt agcgatatcc tggtgttttt
      481 cggcatctgg ctaatattgc cgtttgtctg gcatcggctg gtggttcctt ccagcggcgc
      541 agtggcggcg ctggtcgtgg cgctgctgat tagcggcggc attctgacct gggctggctt
      601 caacgacccg caggagatca acggtacgct tcgcgccgac gccacgcccg ccgcaacaag
      661 ttcgtcgatc gccgacgaag actggccggc ctatggacgt aatcaggaag gccaacgcta
      721 ttcgccgctg aaacagatca ctgcggataa cgttcaccaa ctgaaagaag cgtgggtctt
      781 ccgcaccggc gatctgaaac aacccaacga tccgggtgaa atcaccaacg aagtgacccc
      841 gataaaagtc ggtgatacgc tttatctgtg tacagctcac cagcgtctgt tcgcgctgga
      901 cgccgccagc ggtaaagaga agtggcattt tgatcctcag ttgaagaccg attcgtcttt
      961 ccagcatgtg acctgccgcg gcgtctctta tcatgaggcc aaagcggata ccgcctcgcc
     1021 ggaggtcatc gccgactgtc cgagccgcat tatcctcccg gtcaacgacg gtcgcctttt
     1081 cgcggtgaat gccgaaaccg gcaagctgtg tgaaaccttc gccaacaaag gcgtcctgaa
     1141 tctgcaaacc aatatgccgg ataccacgcc gggactgtat gaaccgacgt cgccgccgat
     1201 tatcaccgat aaaacaattg tcattgccgg ttcggtcacg gataacttct ctactcgcga
     1261 aacgtccggc gttatccgtg gttttgatgt taatagcggt aaactactgt gggccttcga
     1321 tcctggggcg aaagatccga acacgattcc agccgatgag cacgctttta cctttaactc
     1381 gccgaactcc tgggcccctg ccgcctatga tgcgaaactg gatctggtct atctgccgat
     1441 gggcgtgacc acgccggata tctggggcgg taaccgcacg ccggagcagg aacgttatgc
     1501 cagctccatc ctggcgctga atgccaccac cgggaaactg gcctggagtt atcagaccgt
     1561 ccatcacgat ctgtgggata tggacctgcc ggcacagccg acgctggcgg atattaccgt
     1621 tgacggtact accgttccgg ttatctatgc accagcgaaa accggtaata tctttgtgct
     1681 ggacagacgt aatggcgagc tggtcgtgcc cgctccggaa aaaccggtcc cgcagggcgc
     1741 ggcaaaaggc gattatgtcg ccaaaactca gccgttctct gatttaacct tccgcccgaa
     1801 aaaagatctc tccggcgcgg atatgtgggg cgcgaccatg ttcgaccaac tggtgtgccg
     1861 cgttatgttc caccagttgc gctatgaagg tatcttcacc ccgccatccg agcaggggac
     1921 attggtattc cctggcaacc tggggatgtt tgaatggggc ggtatttccg tcgatccaga
     1981 ccgtcaggtc gctatcgcta acccgatggc gctgccgttt gtctcgaagc tgatcccacg
     2041 cggcccgggt aatccaatgg aaccgccgaa agacgcgaaa ggtaccggta cagaagcggg
     2101 tattcagccg cagtacggcg taccgttcgg cgtcacgctg aatccgttcc tttcgccgtt
     2161 tggtttgccg tgtaaacaac cggcctgggg ctacatttcc gcgttggatc tgaagaccaa
     2221 tgaaatcgtg tggaagaaac gtatagggac gccgcgcgac agtatgccgt tcccgatgcc
     2281 ggttccggtg ccgttcaaca tggggatgcc catgctgggc gggccaatct caaccgccgg
     2341 taacgtgctg ttcattgccg cgaccgccga caactacctg cgcgcttata acatgagcaa
     2401 cggggaaaaa ctgtggcagg gacgtttacc cgccggaggc caggcaacgc cgatgaccta
     2461 tgaggtaaac ggtaagcagt acgtggtcat ttctgccgga ggccacggtt cgtttggtac
     2521 gaagatgggc gactatatcg tggcctatgc tttgcctgac gacgcgaaat aaccattaat
     2581 gcccggcgta tgccgggcat tgtgccgggt agcggtttcg ccttacccgg cctgcgtcac
     2641 agacatcgat tagaccgtaa atcctaacat cattcccgta tcttcatgtt ctaacagatg
     2701 acagtgcgcc atataggcat gttccttcgg cgcgtcgtga tcgaacttga ccagcacttc
     2761 gctgataccg ccctcaacgc gtaccgtatc cttccagccc gttctgtgcg ccgctggcgc
     2821 tttgccgttc tctgacaaaa tacggaactg ggtgccgtga atatggaaag gatgcagcat
     2881 catgtcaccc acgccggaaa tcacccaacg ttcatgtcgg cctttttgcg ccgcgaacat
     2941 cggtttgttc atatcgaaga cctggccgtt gataaagtta gcgttatgga agtcgaattt
     3001 tccgccgtga ttcatattgc ccatcgcgcc atgattcatc ccgctgtgat ccatgttgcc
     3061 atgatccatc tcgccatgcc ccatattgcc gccctgcata tgcgcgttca tgctgtcatg
     3121 atccatgccg ctcatcgcct gagcgccata tttcttcatc agcatttgca tccccatcat
     3181 atcaaggcgc gggtccatcg acagtttcag gttgcgcacc gtcagccctt ccagcgacgg
     3241 cagcgccggc atcgtcgtca acgtatccgg cagcgtaccg gaggcggtaa tccgcagcgg
     3301 ctggatacgc atcaccggat gcggtttatc aaacggagcg atcgccattc ccatctggct
     3361 gaccggcagg gtcaccagat caaaggcttt cccgtcgctg atatccacca gcacttcaaa
     3421 acgctcgccc attaataacg gcagttcggt gactttcacc ggctccgcca gcaggccgcc
     3481 gtcgctggcg atcacataaa gcggacgatt atcgctggcg gcgatattca gcgaacgcgc
     3541 attacagcca ttcagcaagc gcagacgtag ccagcctttc ggcgcggaat gctgcggata
     3601 gatagcgcca ttggtcagca gcgtatcgcc aaaccagccg acggcggcgg tcataatatc
     3661 cagttgataa tcaatctggc catcggcgga gaagcgtttg tcctgaatga tcaccggcac
     3721 atcgtcgata ccccactgtt tcggcaggcg caatttgcga atctcgtcat cttcaatcag
     3781 caccagtccg gcgaggccca tcgccacctg gcgcccggtt ttgccgtgtt tgtgcggatg
     3841 aatccagcag gtcgcggcgc gttgctgcgg cgtaaacgtc accgtgcggg ttccgccagc
     3901 gggaataatc ccctgcgggc cgccgtcaac gatgcccgga atctccagac catgccagtg
     3961 aagcgtcgtg tcttcggcca gttggttatg gatatcaacg gtcacgcttt ttcctttgtg
     4021 aagctgtacc gctggcccca gcaaattacc gttgtagccc caggttgtcg cgttcttacc
     4081 ggcgaatgtc gactgtccgg ctttaacaat taactgcata cggttgctcg catctgccgt
     4141 taacaggtca ggaataggca acgcgggacg ttcggcggca aaagcggcgc ggctccacag
     4201 cggcagcgct gatgcaaccc ccagcgccac tgaatatttt aagaaatcac ggcgtaacat
     4261 aatcatttcc ttataatgaa caggcgggtg tctaagctta gaccctgccc taacgggaag
     4321 gtcaagccag caacacgtct ttaccgttcc tgacagcaat acaacaagaa tgaaaacgcc
     4381 gcgaccaatc ctgataataa aagtcgtcgc tacgttctca gtatgctaac gttgactttc
     4441 cctgatgccg tggtagaagc aatgaagacg tttttcagac ccgtgttgtt tggcagcctg
     4501 atggccttat gcgcaaatag ctatgcgctt actgaatccg aagctgaaga tatggccgat
     4561 ttaacggcgg ttttcgtttt tctgaaaaat gactgtggtt accaaaattt acccaacagt
     4621 cagattcgcc gtgcgctggt cttttttgcc cagcaaaatc agtgggacct gagtaactac
     4681 gacaccttcg atatgaaatc gttgggcgaa gacagctacc gcgatcttag cggcatcggt
     4741 attccggtcg ctaaaaaatg caaagctctg gcccgcgatt ctctgagcct gttagcctac
     4801 gttaaataat cctccgcgat cctattgctg aaataatgac cgtgcatcca cggtcattgt
     4861 tagctatgat gttgcgccct ttttttacgg gtgttaacaa tggaggtatc agccaatggc
     4921 cgaaaatacg atgtggcatg aaacgctaca cgaccagttt ggtcagtact ttgccgtaga
     4981 caacgttctg tatcatgaaa aaaccgatca ccaggattta atcatctttg aaaacgccgc
     5041 ttttggccgc gtgatggcgc tggacggcgt ggtacagacc accgaacgcg acgagtttat
     5101 ttatcatgaa atgatgaccc atgtcccgct gctggcgcac ggtcatgcga aacacgttct
     5161 gattatcggc ggcggcgacg gcgcaatgct acgtgaagtt acccggcata aaaacgtcga
     5221 aaccatcacc atggtagaga tagacgctgg cgtagtctcg ttttgccgcc agtatttacc
     5281 caaccacaat gccggcagct acgacgatcc gcgctttacg ctggtgatcg acgacggcgt
     5341 gaatttcgtc aatcagaccc atcagacctt tgatgtgatc atttccgact gtaccgatcc
     5401 gataggcccc ggcgaaagcc tgtttacctc cgccttttat gaaggctgta agcgttgcct
     5461 gaatccgggc ggcatttttg tcgcccagaa cggcgtgtgc ttcctgcaac aggatgaagc
     5521 gctcgacagc caccgcaagc tgagtcatta cttcagcgat gtcggcttct accaggcggc
     5581 gattccgacc tattacggcg gcattatgac cttcgcctgg gcgacggaca acgacgctct
     5641 tcgccacctg tcgagcgaaa ttattcaggc gcgttttcat gccgccggcc tcaaatgccg
     5701 ctattacaac tcggctattc atgccgctgc atttgcgcta ccgcaatatc tacatgacgc
     5761 actgtccgca cagtgacgtt aaggaggtga taaaaattga aaaagctgaa actgcatggc
     5821 tttaacaatc tgacgaaaag cctgagtttt tgtatttacg atatctgcta cgccaaaacc
     5881 gcagaagagc gcgatggcta tatcgcctat atcgatgaac tctataacgc caaccgactg
     5941 accgagatcc tgtcggagac ctgctccatt atcggcgcga acatcctgaa catcgcccgt
     6001 caggattatg aaccccaggg cgccagcgtc acgattctgg tgagcgaaga gccgatcgac
     6061 ccgaaactta tcgaccaaac cgaacatccc ggcccgctgc cggaaaccgt ggtggcgcac
     6121 ctcgataaga gccatatctg tgtgcatacc tatccggaaa gccatccgga aggcgggctt
     6181 tgcacctttc gcgccgacat cgaagtgtca acctgcgggg tgatttcacc gctaaaagcg
     6241 ctcaattacc tgatccacca gctagagtct gatatcgtca ccatcgatta ccgcgtgcgc
     6301 ggctttacgc gcgacgtcaa cggtatgaaa cactttatcg atcatgagat taattccatt
     6361 cagaatttta tgtcggaaga tatgaagtcg ctgtatgaca tggtggatgt aaacgtgtat
     6421 caggaaaata ttttccatac caagatgctg cttaaagagt tcgatcttaa gcactatatg
     6481 tttcacacca aaccggaaga tctcactgaa accgaacgcc agcagatcac cgccgcgctg
     6541 tggaaagaga tgcgcgagat ttactacggc cgcaatattt ctgcggtctg attcaccact
     6601 ggcagcgcct gacggcgctg tcactccggc tgcaccagcg ttagcgcaaa agcgcgccct
     6661 tttagttcaa cctgcgctga cggcggcaga ttgacgtcgg taatcacatc attaaagcgc
     6721 tcaagcggca ccacattaaa gagcgaatgc gcgccatact tactgctgtc cgccagcaac
     6781 actttgcgct gcgcattagc aataatctcc tgtttaagcc cggccttatc ttccgttggg
     6841 gtcgtcacgc ccgtttttac cccccatgaa ttacagctca taaacgcgat gttcggataa
     6901 acgctgcgca acagcttgcg cccatgctca ccgatacagg actgactgct gtcatcgata
     6961 cgaccgccga caatcgtcac ttcaatttgc cggaactcag ctaaaaacag cgcaatatgc
     7021 agatcgacgg tgatgacccg cagcggaaga tgggttaagc atttcgccag ttccatcatt
     7081 gtcgtaccgg catccagcac gacggcatcg ccagcattga ccagcgatgc ggcaacgcgt
     7141 gcaatcgccc gtttttcagc gggcgatcgc agttgttttt cattggtggt gggctgggcg
     7201 ggttcaaaac gccgcagcgc cacgccgcca tgactacggc tgatcacgcc ctgctcatcc
     7261 agcttgatca aatcgcgacg gatagtggct ggcgatgcgt caaccgcctc aaccagctgt
     7321 tctaccgtaa ccagcgtatg gtttttcaga tacgccacaa tgagatccag acggtgttgt
     7381 cctttcataa cagggaatta tgccagttgc attgccagtt tgatcgatac ggccatgctc
     7441 tcagattttg cttttcccgt ccaggcgata tcaaatgcgg tgccatgatc ggcagaggtc
     7501 cggataaacg gcagccctgc ggtgatattc acgccatcat aaaagccaag caatttcaac
     7561 gggatatgcc cctggtcatg atacatcgcc accaccatat catactgtcc ctcataagcc
     7621 tggagaaata cagtatccgg cgggcacggc ccataaacgt ccataccttt tgcgcgggca
     7681 tcggtaatgg ctggcgtcag gatacgcgtc tcttcatcgc caaacagacc attctcgccc
     7741 gcatgaggat tcacgcctgc cacggcgata cgcggtttaa cgtaacccac acgcttgagg
     7801 aaagtatcag caataccaat caccgtttcg acacgcgtgg tacttaacgt atcaaggaat
     7861 ttacgcagcg cgatatgcgt tgaaacgtga atcactttta gtttatcggt gtaaagtacc
     7921 atcgcgtaat cgcggctatg ggtcagagtc gcgagcagct cggtatggcc cggatagttg
     7981 tgccccgcca ggtgcagcgc ctctttattc agcggcgcgg tagcgatagc ctgtacgtcg
     8041 ccccgtaacg ctaactcggt ggcgcgcttc acgcagcgat acgctaaatc ccccgcctgc
     8101 gcctgaactt tcccggcctc cagcgcctcc ggctgcgcca gcggctcatc aatcacatga
     8161 atgatgccgg gcgcaaaacg cgcttcggcg acccgttcaa tggcccgtaa ctcgacgttc
     8221 ggcgtgatgc ccttcgcctg taaacatttc aaggttgcga ggcatccaat caccaccagc
     8281 ggcgcgccgt tgagaccgtc ttcacttagc gctttaacaa taatttccgg cccaatgccc
     8341 gctggatcgc ccatggtaat ggcaacggtt ttagtctcca caatacatct cctcaatata
     8401 ataaagcgcg tcacacaacg tactgtctga accgaatccg cccgctttgg taatgaccgg
     8461 cagatcgtca atttcgctgt ttacaaacgt tccacaggga atacagggcg ccacctcgct
     8521 ctgaatgcga taaccttcag cgccaagcgc gccggcgacg gcggtagcga tatcgccgcc
     8581 ggtcagaaac agcccgccaa tccgcgcctg ctcgataata tttaacgtga cgacgccaag
     8641 ccgatgactc agtcgctcgc ccaattgctg acggctcatc gcggattttt cgcacagcgc
     8701 gtcgattaac tgtcgatctt ctgcgcgacg gctggtgcgt aaaatcgtat gtcgatgctg
     8761 acttaacagc gcgcaggcct gctctacgac agacgcgatt tcctgctccg cgctatccga
     8821 caccatgcgc gcggcatcga tatccacgac ctccgcacgt ccccggcaca gcgcattatc
     8881 cacctgacgt cgcgtggctt cgctcatcga accggctacc accagtaccg gtagccgctg
     8941 ccggtcttgc ataaaaagtt caaccggcaa cgcattcgcc agaccagctg cgccgacgag
     9001 cagcggcatc gacggttgtt cgcacgccgc ttgcgcaatc aacgtcaggt cccgctcttc
     9061 taccgcatcc acgacgataa tcccttcgcc ctcagccgca taagccgtaa gtaaggcgct
     9121 taacccgccg cgtcggacat cctgtaaaaa gacttcatac acagggatct cactttgcaa
     9181 cgccactatc tcggcaatac gggaagagac aatgggcgtt ttcggatcgc tagcaaattc
     9241 ggtttccagt agcggggcgc cattaaccag acattttcct tcaagcgtcg tgcgtccggc
     9301 cgcagggatc gcagcagcga taacggccag ttttcgctga ctggcgcgca tagctgccgt
     9361 cacttcggcg ccgatattgc cgcgaaatgt ggagtcgatt tttttgtaca ccagcggcgc
     9421 tggcgatgtc tcacaccacg gggaaagcgc ggcataaacg gcagatgccg cctgatctgc
     9481 gggcatcgcc cggctttcgg tgttaatgac taacacatcg gcgcggcggg acggtttttg
     9541 cgacgcgctc aacatgactt ccgttctcgc ccccttcttc gccaactgga cgccggtatc
     9601 attcgatccg gtaaaatcat cggcgataac catcattttc atgcgttttt ctccaaagaa
     9661 gcctgacgcg cctgtttttt cgcaacccag gaggtcaaca ctggcgtcag gattgccgtg
     9721 gtgatcaccg aggcggcaat cagcggagcg gcagcagcgg ccacctcggc gagcgaaggg
     9781 tcggcctgcg caatagccag cggcgtcgca acggcattac ccgcagtgct ggaggccgcc
     9841 gccccggcaa tgccagttcc gccaaccaga cgatctgcgc gaatattaaa gaaaccgcca
     9901 acgaacgttg tcagcacgcc gagcagaatt ccggcaagtc cgccttgcag taacatttcc
     9961 aggttgatgc ccgcccccag cgcaaaagca aagaaaggaa tgagcagcgg gccgcctttg
    10021 gtcaaaaaat cgcgcatatg aggatcaaga ttgccgagga tcatgccgac aaccagcgga
    10081 accagcaccg ccaccagcgc cataatggga atgttcgcca tccctgccgc gcccagcgca
    10141 atcatcgtaa agaaagggcc atcattaaga gacaaaatag agatagcgcc gacgtcgcgc
    10201 tcattgccga attcgcctac caacgcagca taaagtccgc cattcgaatt gctcatcgcc
    10261 gcgataatcg ccacgccgct caggccaaaa ataccctccg cgccgaaaag atgctccacg
    10321 cccaggccaa tgccgatggc gacaagcaac ttagtgagcg taatcgtccc gccctgcaat
    10381 aacgcctggg gcgcggcttt cacactgata ccggctccca tacacagcag aaaagcgcca
    10441 atcagcggcg ccgcgccgtt tttaaataag gcagtggtaa aaccgccaat ctcaagcgcc
    10501 tgcggggcga aggtgttaat gactgcgcca ataacgagcg gtacgaccat catgccgccg
    10561 ggtacgcgct ctattgcttt tttgatgttc atggtcttac cgcctgttgc ttgttgtgat
    10621 tgaataaaat cataacgatt atattcaatc aaattaagat cacaaacgcg tcagatcaca
    10681 gttttaaaat gattaataaa aatcaaaaaa tcattctgca ataaaaaagc cgggatactc
    10741 ccggctggaa tgtgtggtga tttcgtttcc actaccgccc ccaactgtcc gtcgacaggc
    10801 gttgcggggc aataacgaag agagggtcag gctttactga cgaattcccg atacgcggcg
    10861 acgacccgca gaaaatcctc catgccgcac agggataaac tctcttcatc gtaataactc
    10921 atcccctctt ccatctcatc gccggaaaaa tccagctgat tggcgcgaat catcacttct
    10981 tcgccgtcca tccagatcgt gtactcatgc cctgctcgtt gccaggaacg ttcgctgcct
    11041 ttgaccgtac gcgcggcttg ttctacttca tccagtagcg agaggttgtc tttaacctct
    11101 tcattaaacc agtgaccgac cacctcgtgg cccatcgaca ttcgtaccaa aacccgtccg
    11161 gtcacatcgc gcagaaattc gtaatccata atgtgttcct ctgcaaagcc cttacagtca
    11221 ttatcgcagc agcggagaag aaaaaaagcg ggaacagcag gcggaatgaa aataaaaacc
    11281 caccgcagtt gcgatgggtt ttgtaggccc ggtaagcgta gccgccaccg ggcaataaga
    11341 ggcgtaggca tggtaagcct gacgccgtca ggcaaattat accgcagtct ggaaaatcac
    11401 cccatccgct ttctcagtgt actgagagag ctggtcgaag ttcagataac ggtaggtatc
    11461 caccgccgtc ttatccacct gcgccacaaa ggtctggtac tcttccggcg tcggcagttt
    11521 gccaataagc gctgcaaccg ccgccagctc cgcagaagcc aggaagacgt tcgcaccagt
    11581 acctaaacgg ttcgggaagt tacgggtaga agtggaaacc accgtcgcgc cgtcagccac
    11641 acgcgcctgg ttacccatac acagggaaca acccgggatt tcgatacgcg caccgctctt
    11701 accaaacacg ctgtagtaac cttcttcggt cagctgcgca gcgtccatac gggttggcgg
    11761 cgctacccac aggcgggttg gcaactggcc tttgtggcta tccagcagct taccagccgc
    11821 gcggaagtgg ccgatgttgg tcatgcagga accgatgaac acttcgtcga tcttctcgcc
    11881 ctgcacgtca gacagcagac gcgcgtcgtc cggatcgttc ggcgcacaga ggattggctc
    11941 tttgatatcc gccagatcga tgtcgatcac cgctgcgtat tccgcgtcag catcggcttc
    12001 cagcagctgc gggtccgcca gccatttttc cataccctgg atacgacgtt ccagcgtacg
    12061 acggtcgccg tagccttcgg cgatcatcca cttcagcagg acgatgttgg aggtcaggta
    12121 ttcaacgatc ggctctttgt tcagcttgat ggtacaaccg gcagcggaac gctcggcaga
    12181 agcatcggtc agctcaaacg cctgctcgac tttcagatcc ggcagacctt cgatttccag
    12241 gatgcggcca gagaagatgt ttttcttgcc tttcttctca acggtcagca ggccctgttt
    12301 gatggcgtac agcgggatgg catggaccag atcgcgcagg gtgatgcccg gctgcatttt
    12361 gcctttgaag cgcaccagca ccgattccgg catatccagc ggcatcacgc cggtcgcggc
    12421 ggcaaacgcc accagaccag aacccgccgg gaaagagata ccaatcggga aacgggtatg
    12481 ggagtcaccg ccggtaccga cggtgtccgg cagcagcata cggttcagcc aggagtggat
    12541 cacgccgtcg cccggacgca gggagacacc gccgcggttc ataatgaagt ccggcagcgt
    12601 gtggtgcgtg gtgacgtcaa cgggcttcgg ataggctgcg gtgtgacaga acgactgcat
    12661 gaccagatcg gcggagaatc ccagacaggc caggtctttc agctcatcac gggtcatcgg
    12721 gccagtagta tcctgagaac cgacggaggt cattttcggt tcgcagtacg cgcccggacg
    12781 aatgcctttc acgccgcagg cgcgaccgac cattttctgc gccagagaga agccacggct
    12841 gctttctgcc acgtcttttg cctgacggaa aacgtcagag tgcggcagac ccagcgcttc
    12901 acgcgctttg gtggtcaggc cacgtccgat aatcagcgga atacggccac cggcgcgtac
    12961 ttcgtcgatc agcacgtcgg ttttcagttc gaaggttgcc agcagttcat cggtttcatg
    13021 attgcgcact tcgcctttgt acgggtagac gtcaattaca tcgcccatgt tcaggttaga
    13081 aacgtcaact tcaatcggca gcgcgcccgc atcttccatg gtgttaaaga agataggcgc
    13141 aattttgccg ccgaggcaca gaccgccgcc gcgcttgttc ggcacgttcg ggatgtcatc
    13201 gcccatgaac cacagcacgg agttggtcgc ggatttacgg gaagaaccgg tgcccaccac
    13261 gtcacccacg taggccagcg ggtagccttt tttctgcaat gcttcgattt gtttgatcgg
    13321 gccgacaacg cctggctgat ccggctcaat gccttcacgg gcgtttttca gcatcgcctg
    13381 cgcatgtaac gggatatccg gtctcgacca cgcatccggc gccggagaga gatcgtcggt
    13441 attcgtttcg ccggtcactt tgaaaacggt gacggtgatt ttttccgcca gcggcggacg
    13501 gctcaggaac cattcggcgt cggcccaaga ttgcatcacc tgtttggcat attcattgcc
    13561 cgctttggct ttctcttcta cgtcgtagaa gttatcgaac atcagcaggg tgtgagacag
    13621 cgctttggcc gcaatcggcg ccagtttcgc atcgtccagc gcgtcaatca gcggatgaat
    13681 gttgtaacca ccctgcatgg tgcccagcag ttcaatggct ttttctgggg agaccagcgg
    13741 ggaggtggtg tcgcctttcg cgacagcagc gagaaaaccg gctttaacat aagcggcttc
    13801 atcgacgcca ggaggaacgc ggttgatcaa caggtctaac aggaattctt cttcgcccac
    13861 aggcggggtc ttcagcagct cgacaagcgc agccatttgg gttgcgtcta aaggtttcgg
    13921 cacaatcccc tgggcagcac gctcagctac gtgcttacgg tattcttcta gcacgacgat
    13981 atctcctcgc tctcattgtc ataatgcggc gcttttgttg atgggcgatt ctcttcacgc
    14041 tcctgtgaga cagtagttag tagggtaaat gcccggtacc gcataaggca caataacagg
    14101 attttcttta agtgttaatc tgtttacaaa aaagcaacat aaaaaagtgg ctgaatcgtt
    14161 aaggatggtc taatgctcta ctgagacggg agctgcagcc ataaatgctt acctcatttc
    14221 gtgctttgat cgtcacgtaa cgttaccgat cccaacatta gctaaaaatt aaactatcgt
    14281 ccctttatac tcacgccaaa ctgcaccccg tcggcggcag gcataatgac catagcgatt
    14341 ctcgggaatc gggagagata aaatgacgtt gccctttaaa ccccatctca ttgcccttgt
    14401 gtgcagtgcc gggttatttg ccgcttcggg cgtactgtat gttaaaagcc gcgctcccga
    14461 agcgcccgcg caggcggcag ctcccacctc tgagccaacg cagaccgctg tgcccgcgcc
    14521 tgtcgcgaaa acgaccttta ccactgcgca aatcgatcaa tgggtcgcgc ctgtcgcgct
    14581 ttatcccgat gccctgcttt cgcaggtgct catggcctcc acctacccgg cgaacgtggt
    14641 tcaggccgtc cagtggtcgc gggataaccc cacgctgcag ggcgatgccg ctattcaagc
    14701 ggtggccagc caaccgtggg accccagcgt caaatcgctg gtcgcctttc ctcagttgat
    14761 ggcgcttatg ggcgagaatc cgcaatgggt gcaaaacctg ggcgatgcgt tcttagccca
    14821 gccacaggat gtgatggatg cggtgcaaag gctgcgtctg ctcgctcaac aaaccggttc
    14881 gctaaaatcc acgccacagc aaaccgtcac cagcgtgccg aagtccagcg cttctaccgc
    14941 cgtcacgacg acaaccacca catccgccag tacgccagca acaccgtcga ccgtcatcaa
    15001 aattgaacct gcgaatccgc aggtggtgta cgtgccaaac tataacccca cgacggtgta
    15061 tggcgcctgg cccaataccg cttatccgcc ggtgtattta ccgccccctc cggggcagca
    15121 gtttgccgac agttttgtta aaggttttgg ttatagtctg ggcgtcgcca ccacctatgc
    15181 gttgttcagc agcatagact gggatgacga cgatcatcac caccatgacg acgaccatca
    15241 tgatgatgat taccatcatg gtggtaacgg ttatcaacat aatggcaata atatcaacat
    15301 caatgtcaat aatttcaacc ggatatccgg gcaaaacctg ccgggccaaa cgatgggctg
    15361 gcagcataat cccgcctggc gcaatggcgt cccctatccg aataataccg ttgcgcaacg
    15421 gttccatccc accaatgtta gcggcgggtt aagcgcaacg cagcaagcgc cagtgtctcg
    15481 cgacagtcag cgccaggcag ccatggcgca attccaacag cgcagccata catcacccgc
    15541 taacgtgtca ggcgagacat cccgcgacag acagcgcaaa gcggcatcgc agcagttaaa
    15601 tcaaattgcc cagcgtaata attaccgtgg ctatgacgga acacaaaaca gcagtcgtcg
    15661 cgaggcggcg cagcagacac tgaataaatc caccacgcag cagcatcgtt ccgagctgaa
    15721 ggctaaagcc cagcagcacc ctgtttcaca acagcagaga gacaccgccc gccagcgtat
    15781 tgaatcctct acgccacagc agcgtcaggc atttcgccag aatatgcacg ccaatgtgtt
    15841 tagcgggaac gacagtcgat cgccgtcatg gcaatcgcaa cagctacgcg gcctagaaag
    15901 ccgtcgcggc agtcacttga acaccgagca acgcgccgcc gcgcgggaac atttttctga
    15961 acatcatgaa tttcatcgcc gttaaccgga gcagataatg aaaaaggtta tgttaagcgc
    16021 tctgttactg tcgttaccct tgctgggcta cgcgcaggaa cggttcccct ccccggaagc
    16081 ggccgccagc gccttcgccg cggcggtagc cggaaaaaac gaaacgcagc ttaccgcgct
    16141 actgggcgat gactggcggc aatttctgcc gccggaaggt gccgatcccg aggccgtggc
    16201 ccgcttcaat cgtgactggc gcgaaggcca tcgcattgta caaaaagaca atacggcgca
    16261 cctgaatgtc ggacgagaag actggcagct cccggtgccc atggtgaaag agactggcgg
    16321 ctggcgcttt gatatggcgg cagccgggaa tgagatcctc acccgtacta ttgggcgaaa
    16381 tgaactttct accttacagg ccatgcatgc ttacgttgat gcgcagcagg actattactt
    16441 acaaaaccat cgctgggcgc acaggataat cagtagcgaa ggccaaaaag atggcctgta
    16501 ctggccaacc aaagcaggcg acgtccccag tccgttaggc ccaaacttta gtcccgcagc
    16561 gccagacgag ggttaccacg gctaccattt ccgtattatc agcgataacg acggtcacgg
    16621 tgcggcgctt ctggcctggc cgatgcatta cggcgaaacc ggggtgatga gttttatggt
    16681 caaccaggac gatcgtattt atcaggcgga tttaggcaag gagacggaga gtaaagttca
    16741 ggctatcacg cgttttgcgc cagacgcgca gtggcaggtc gccgaataac ccgtaagcgc
    16801 ctggcgttat cgccaggccg tgatcattag ccctgatgcg gcatcaattc cgggtggcct
    16861 tgtaccggcg gcttgttgct ggtcagcgcg gcttcatcag cctgaatgct gccggaattg
    16921 gccgcccata cgccttcatg cgtgtgggtg atctgctgat gctgcgcatt caaatcctcg
    16981 cccattgccg caatatgcgt gctttccgta ccgccgctgt tagtcgccca ggggatgacg
    17041 ggatcgctgg caaatgccat gccggaaatc aaggtcgcag ttagcgctgc cgttgtcaga
    17101 aaaagtttca tatatcaaac ctcataatta gctcgctatt attttatagc gttaccaatt
    17161 tcaggatgat gacaaattaa ggagaggtat ttcttatgaa acaattagtt ggtcgaaaat
    17221 gacagacaaa ggcactaccg acggcataag ctttgaaaaa cgtactgctg cggaaaggat
    17281 aaattttgcg gtttcgttat ccttcgccat catttgacac atctgatttg ccatgcataa
    17341 aaaaagcggc tgtaaagccg cttttctgta tcgggtggcg cattgccacc cgcagaagat
    17401 tatttcttct tcgctttcgg gtttggcagg tcggtaatgc taccttcgaa gatttccgcc
    17461 gccaggccca cggactcatg cagagtcggg tgagcatgga tggtcagcgc gatatcttcc
    17521 gcgtcacagc ccatttcgat cgccagaccg atttcaccca gcagctcgcc gccgttggta
    17581 ccgacaatcg ccccgccgat cacgcggtga gattctttgt cgaaaatcag tttggtcata
    17641 ccgtctgcgc agtcagaagc gatagcacgg ccagaagctg cccacgggaa ggtggcggtt
    17701 tcatagctga tgcctttttc tttcgcttct ttctcggtca ggccaaccca tgccacttct
    17761 ggctcggtgt acgcgataga cgggataact ttcggatcga agtagtgttt cttcccggcg
    17821 ataacttcag cggcaacgtg gccttcgtga acgcctttgt gcgccagcat cggctgaccg
    17881 acgatatcgc cgatagcgaa gatgtgcggc acgttggtgc gcagctgttt gtcgacgcgg
    17941 ataaagccac ggtcgtcaac ttccacgcca gctttgcccg cgtcgaggtt tttaccgttc
    18001 ggcacacgac caatcgccac cagaaccgca tcataacgct gcgcttcagc cggggctttt
    18061 ttgccttcca tcgaaacgta gataccgtct tctttcgctt caacggcagt cactttggtt
    18121 tccagcatca ggttgaattt cttgctgatg cgtttggtga agactttaac gatgtcttta
    18181 tcagccgccg ggataacctg gtcgaacatt tcaaccacgt caatctctga acccagcgcg
    18241 tggtatacgg tacccatttc cagaccgatg ataccgccgc ccatgaccag catacgcttc
    18301 ggcacttctt tcagttccag agcgtcggta gaatcccata cgcgcgggtc ttcatgcgga
    18361 ataaacggta attggatcgg acgagaaccc gccgcgatga tcgcgttatc gaagttgatc
    18421 acggttttgc cattttcgcc ttccacttcc agggtattag ccccggtgaa tttacccaga
    18481 ccattgacca ctttcacttt acggcctttg gccataccag ccagaccgcc ggtcagctgc
    18541 gtgatcactt tctctttcca ggtacgaatc ttgtcgatat cggttttcgg ctcgccgaag
    18601 acgataccgt gttcagccag cgctttggct tcttcgataa cttttgctac gtgcagcagc
    18661 gctttagaag ggatacagcc gacgttcaga caaacaccgc caagggtgtt gtagcgttct
    18721 acaattacgg tttccagacc taaatcagcg caacggaaag cggcagaata gcctgccggg
    18781 cccgccccaa gtaccacgac ctgagttttg atttcagtac tcatcatgac ctctttattt
    18841 gtatccggcg gtccggggta cttgatcgcc catcatccac cgggtcgttc tatccgcccg
    18901 tatcttacaa aattgttaac aattttgaaa caacaaacgg atcacgaatt atcgctttcg
    18961 ctaataacct cacaaactcc atgagattat caaaaaaaag ccggccgtcg ggccggcttt
    19021 ttcgcttaca tcaccagacg gcgaatgtca gacaacatat tgttgataat ggtaatgaaa
    19081 cgcgcaccat cagcaccatc gatcacacgg tggtcgaaag aaagagagat aggcatcatc
    19141 agacgcggca caaactcttt cccattccac accggttcca tcgccgactt agaaacgccg
    19201 aggatagcca cttccggcgc gttgacaatc ggcgcaaagt gggtagttcc caggccgccg
    19261 atgctggaga tagtgaagca accaccctgc atttcgccag cggtcagctt accatcacgc
    19321 gcttttttgg agatggtggt cagttcacga gacagctcgg tcacgctctt cttattcacg
    19381 tctttaaaga ccggaaccac caggccattc ggggtatcaa ccgccacgcc gatgttgatg
    19441 tattttttca gggtcagacg ctgaccgtct tcggatagag agctgttgaa gcgcggcatc
    19501 tgttccagag cagcggcaac cgctttcatg atgaagacca ctggcgtgta tttcacatcc
    19561 agtttgcgct tctcagcttc ggcgttctgc tgtttacgga acgcttccag atcggtgata
    19621 tcggttttgt cgaagtgcgt aacgtgcggg atcatcaccc agttacggct caggttcgcg
    19681 ccagagattt tctggatacg gcccagttcc acttcttcaa cttcaccaaa cttgctgaag
    19741 tccactttcg gccacggcag catacccggg ataccgccgc ccgcagcagc cggcgcagct
    19801 tccgcgcgtt tgatagcgtc tttcacgtaa gcctgaacgt cttcgcgcag aatacggcct
    19861 ttacgaccag tgcctttcac tttcgccagg ttgacgccaa actcgcgcgc cagacggcga
    19921 atcagtgggg tagcgtgaac gtaagcgtcg ttttcagcga actcagattt gccttcggct
    19981 ttggcagccg gggcagcagg cttctcagct ttcgccgccg gagccggcgc cgctgcttcc
    20041 tgtttagccg gagcggccgc aggcgctgcg ccttccactt cgaagaccat aatcagcgag
    20101 ccggttttca ctttatcgcc ggtgctgatt ttgatttctt tcacggtgcc cgcgaacggc
    20161 gcaggcactt ccatagaggc tttgtcgcct tccacggtga tcagcgactg ttcagcggta
    20221 actttatcgc cgactttgac catcacttcg gtgacttcaa cttcgtcgcc gccgatgtcc
    20281 ggtacgttaa cgtctttcac gcccgtcgct gctgctggag cagccgcagc cggagcggct
    20341 tccgctttcg ctggtgctgc tgcgcccgct tcacccgcca cttcgaagac cataatcaga
    20401 gagccggtag acactttatc accggtgttc actttgatct ctttcacggt gcctgcaaac
    20461 ggagcaggaa cttccataga ggccttgtcg ccttcgacgg tgatcagcga ctgttcagct
    20521 tctacggtgt cgcccacttt caccatcact tcagtcactt caacttcgtc actgccgata
    20581 tccggaacgt gaacgtcttt cgccgctgcc gcagcaggtg ctgctgccgg cgccgcttct
    20641 ttcttctctt ctgcctgagc aggcgcagcg tcagctgcac cgtcggcgga atcgaaaatc
    20701 atgataagtg caccggtctc agttttgtcg ccgacagaga ctttgatctc tttcacgacg
    20761 ccagcctgcg gagacgggac ttccatagag gctttgtcgc cttctacggt gatcagcgac
    20821 tgttcagctt caactttgtc gcccactttg accagaatct cggtgatttc aacttcatct
    20881 gtcccgatgt ccggtacttt gatttcgata gccattattc ttttacctct tacgccagac
    20941 gcgggttaac tttatctgca tcgatgttga atttggtaat cgcatccgct accactttct
    21001 tgtcgatttc gccacgttta gccagttcgc ccagcgctgc gacaaccaca taagaagcat
    21061 caacttcgaa atggtgacgc aggttctcac ggctgtcgga acgaccgaag ccatccgtac
    21121 ccagtacgcg atagtcgtca gccggtacgt aagtacgaac ctgctcggcg aacagtttca
    21181 tatagtcagt agatgccaca gccggagcgt cgttcatcac ctgagcgatg tacggtacgc
    21241 gcggggtttc cagcgggtgc agcatgttcc agcgctcaca atcctgacca tcacgcgcca
    21301 gttcggtgaa ggaggtcacg ctatatacgt cagaacctac gccgtaatct ttcgccagga
    21361 tctctgccgc ttcacggacg tgacgcagga tagaaccgga gcccagcagc tgaactttac
    21421 ctttgctacc ttcgagggtt tcgagtttgt agataccttt acggatacct tcctcggcac
    21481 ctgctggcat tgccggcatg tggtagtttt cgttcagggt ggtgatgtag tagtaaacgt
    21541 tctcttgttt ttcaccgtac atacgctcca gaccatcatg catgatgaca gccacttcat
    21601 aagcgtaagc cgggtcgtaa gagatacagt tcgggatagt cagcgactga atgtggctgt
    21661 gaccatcttc gtgctgcaga ccttcgccgt tcagcgtagt acgaccggaa gtcccgccaa
    21721 tcaggaagcc gcgagcctgc tggtcgccag cctgccagca caggtcgccg atacgctgga
    21781 acccgaacat agagtagtag atgtagaacg ggatcatcgg cagatcgttg gtgctgtaag
    21841 aggtcgccgc agccagccag gatgcgcctg cgcccagctc gttgatacct tcctgcagaa
    21901 tctggccttt ctcgtcttct ttgtagtaag caacctgctc acggtcctgc ggggtgtact
    21961 gctggccgtt cgggctgtag ataccaatct gacggaacag accttccata ccgaaagtac
    22021 gcgcttcgtc ggcgatgatc ggaaccagac gatctttgat cgacttgttc ttcagcatca
    22081 cgttcagggc acgcacgaaa gcgatcgtag tggaaatctc tttactttgc tcttccagca
    22141 gcgcgccgaa atctgaaagt tgaggcagct ctaacttctc ggtgaagttc ggctgacggc
    22201 ttggcaggta gccgtgcagc gcctgacggc gttcatgcag gtatttgtgt tcttcagaac
    22261 cttccgggaa ggtaatgtac ggcagttttt cgagatcagc atcggcaacc ggcacgttga
    22321 aacgatcgcg gacgtaacgc acgccgtcca tgttcatttt cttaacctgg tgagcgatgt
    22381 ttttaccttc cgcggtgtca cccatgccgt aacctttaat ggtatgggcc aggattacgg
    22441 tcgctttgcc tttggtttcc tgcgcttttt tcagtgccgc gtagactttc ttcggatcgt
    22501 gaccaccacg gttcagcgcc caaatctgct cgtcagtcca gtcggccacc agcgcggcgg
    22561 tttccggata tttaccgaag aagtgctcac gcacgtaagc gccgtctttg gatttgaagg
    22621 tctggtagtc gccgtcaacg gtttcgttca tcagctggat cagtttaccg ctggtgtctt
    22681 tacgcagcag ttcatcccaa cgaccgcccc acatgacttt gataacgttc cagccagcac
    22741 ctgcaaagat gccttccagt tcgttaacaa tcttgccgtt accggtgacc gggccgtcaa
    22801 gacgctgcag gttacagttg ataacaaaaa ccaggttgtc cagtttttca cgggtggcga
    22861 tggtgatcgc gcctttggat tccggctcat ccatctcgcc gtcgccgagg aaggcgtaaa
    22921 cggtctgttt agaggtatct ttcaggccac ggtgttccag atatttcagg aatttcgcct
    22981 ggtagatagc accgattggg cccagcccca tagagacggt cgggaactgc cagaattccg
    23041 gcatcagttt cgggtgcgga taggaagaga ggccattgcc gtgaacttcc tgacggaagt
    23101 tatccatctg ttcctgggtc agacgacctt ccaagaacgc gcgagcgtag atgcccggag
    23161 agatgtggcc ctggaagtac accaggtcgc cgccatcctg ttcgttgcgc gcacggaaga
    23221 aatggttaaa acagacatca tagatcgtgg cggaagactg gaaggacgcc atgtggccgc
    23281 ccaactcaag gtctttttta gacgcgcgca gcacggtcat gatggcgttc cagcggatcg
    23341 cagaacgaat gcgacgttcc agctccagat tacccgggta ttccggttcg tcttcaacgg
    23401 caatagtgtt gatgtaatta ctggcccctg cgcctgccgc gactttcacg ccgcctttac
    23461 gagcttcaga aagcagttgg tcaatcagat actgagcgcg ctcaacacct tcttcacgga
    23521 taaccgattc gatcgcctgt agccagtcgc gagtttcgat cggatccacg tcattttgga
    23581 aacgttctga catgggggta ttccttatct atctaatacg ttgagttatc tggaacctgt
    23641 cccattaaac tttcgtcaga aagcttaata agacaggttc tgcgtttagt tgccgcgcac
    23701 atttttgcgc gttattcaca acatcttctg gttaacgttc tgccagaaaa aactaattct
    23761 tgcgctgttc caggcggcgt aaagcgcgtt cacgacggct ctcctcacgg cttctgtcca
    23821 gcataatctc ttcgataaac gccagatgtc ggtgtgacgc ttcacgcgct tcttctggtt
    23881 ttccggccat aatggcttca aatatacggg tgcgatgcgt gctcaccagc ggcagcatct
    23941 cccgacgcgc atacagcaat tcgaagttct gccgcacgtt ttgcgccagc atcggctcca
    24001 tacaccttag cagatgaagc aataccacgt tgtgcgccgc ttcggtgacg gcgatttgat
    24061 actggagcac ggcttcggac tcggcatcca gatcgccgga ctcttgcgcc agctcaatag
    24121 cgtggtgcag ctcgcgaata cggtctttat cttcgtcggt gctgcgcagc gccgcgtaat
    24181 aagccgcaat gccttccagc gcatggcgcg tttcgagcag gtcaaactgg gattcagggt
    24241 gatcggagag cagttccacc agcgggtcgc taaagctctg ccacaggctg ctctgcacga
    24301 aggttccgcc gccctggcga cgaagcaaca atcccttcgc ttcgagacgt tgaatcgcct
    24361 cgcgcaagga gggacgggag acgtcgaact gttttgccag ttcacgttcc ggtgggagtt
    24421 tttctccggg acgcaatgtt ccctcaagga ttaaaaactc cagctgctgc tcgatcacat
    24481 cggagagttt tggttggcgg attttgctgt aggccatgat ttcctgtctt aagccatttg
    24541 cccggagtca attggtctta ccaatttcat gtctgtgacg ctaaagtaac aaagtattca
    24601 ccttctgtcc atacaggttt tgattgaaat cagtaaagga ggcacatttt aacaatttta
    24661 cagaaatcac gtttcaaaac tgtaactgtg cacaaatgtt aaatttaccc accaggaggt
    24721 agatttaacg tatttgaaac gataaaaaat ctcatctgaa ccgattcaac agcagatcaa
    24781 atgcattttt atgcataaat aatgaataaa aacaaattaa cctttagaag ggaaaataaa
    24841 aggaggtatt tacaagtgct ttctttttac gcaactcgtc atcacccctg cacaaagcag
    24901 gtgcattcgc ggccacatac cattattctg atcaagacga aagagttgaa gtgacatttt
    24961 aaaaaacgag cttgtaaata aatcaataca aaaagcggaa ttgcaaactt acacacgcac
    25021 tactgcatcg ttcaaaataa gcgcgttatg aataaaccgc gcccgataca cgaggtttta
    25081 tgatggacag tcagcagcac ggcgagcagc tcaagcgcgg cctgaaaaac cgccatattc
    25141 agcttatcgc attgggcggc gcgataggga caggcttgtt cctgggaagc gcctccgtta
    25201 ttcagtcggc ggggccagga attatcctgg gctatgcgat tgcaggcttt attgcctttc
    25261 tgattatgcg ccagctggga gagatggtgg ttgaagaacc ggtcgccggc tcttttagcc
    25321 acttcgccta taaatactgg ggcggctttg ccggattcgc ttccggctgg aactactggg
    25381 tgctgtacgt attagttgcc atggcggaac tgaccgcagt gggtaaatat atccagttct
    25441 ggtatccgga gatccccacc tgggcttctg cggcagcctt ctttgtgatt atcaacgcca
    25501 tcaacctgac caacgttaaa gtgttcggtg agatggagtt ttggttcgcc attattaaag
    25561 tgatcgccgt catcgctatg attctgttcg gcgcgtggtt actcttcagc gataccgctg
    25621 gtccgcaggc caccgtgcgc aacctgtggg aacagggcgg ctttctgccg catggctgga
    25681 ccgggctggt gatgatgatg gccattatta tgttttcgtt cggcggactg gagctggtag
    25741 ggatcaccgc cgctgaagcc gataacccgg aacagagcat ccccaaagct accaatcagg
    25801 ttatctatcg catcctgatt ttttatatcg gctcgctggc ggttctgctt tcgctgctgc
    25861 catggactcg cgtcaccgcc gataccagcc cgtttgtcct tatcttccat gagctgggcg
    25921 atacgtttgt cgccaatgcg ctgaatatcg tggttctcac cgccgcgcta tcggtttata
    25981 acagctgcgt ttactgcaac agccgtatgc tgttcggtct ggcccagcag ggaaatgcgc
    26041 cgaaagcgct gctgaacgtc gacaaacgcg gcgtgccggt gagctccatt ttggtttccg
    26101 ccgtcgtgac ggcgttgtgc gtgctgctca actacctggc cccagagtcc gcattcggac
    26161 tgctgatggc gctggtggtc tccgcgctgg tcattaactg ggcgatgatt agccttgccc
    26221 atatgatgtt ccgtcgcgcg aaacagcagc agggcgtgaa aacccgcttc ccggccctgt
    26281 tttatccgtt cggcaacgtt ctctgcctgc tgtttatggc ggcggtattg atcattatgc
    26341 tgatgacgcc aggtatggcg atctccgtgt ggctgattcc ggtatggctg ctcatcctgg
    26401 gcgtcggcta cctgtgtaaa gaaaaaacgg caaaaacggt gaaagcccac tgatcgtggc
    26461 gttacttttc cgccctcccc gtccggggag ggtgttatct gcctcacagt ttcccacgta
    26521 taaccatttt atccatatca gcggcgtgat cctgctacgc aaaaaaaagc tcgcaggcga
    26581 ataattaccg ccatcatctg atggggagaa gtctcaatgg ataagggcag actttcggta
    26641 agagagaaaa tcgggtatgg catgggtgac gccggatata acattatttt tggcgctatc
    26701 atgctgtttg ttaattactt ttatacggat atttttggtc ttgccccagc gttagtcggt
    26761 gttttactcc tttcagtacg cgttatcgat gccgttaccg atccggtgat gggcgcgctt
    26821 gccgatcgta cccaaagtaa atatggtcgt ttccgcccct ggctactgtg gattgcattt
    26881 ccctacgcgc tgttcagcgt tctgatgttc acgacgccgg actggggcta taacagcaaa
    26941 gttatctatg ccttcgtcac ctattttctg ctttccgtga cctataccgc catcaatatt
    27001 ccctattgct cactgggcgg cgtgatcact aacgatccaa aagagcgcgt agcctgtcag
    27061 gcttatcgct tcgtgttagt cggcatcgcg acgctgttgc tatcgttaac gctattgccg
    27121 atggtggact ggtttggcga cggcgacaaa gccaaaggct atcagttggc gatgaccgtg
    27181 ctggcgatta tcggcatggg tatgtttctg ttctgctttg ccagcgtccg cgaacgcgtt
    27241 cgccctgccg ttccgacgca cgatgatatg aagaatgatt tcaaagatgt gtggaaaaac
    27301 gatcaatggg tacgcattct gctattgacc ttatgtaacg tctgcccggg gtttatccgt
    27361 atggcggcga ccatgtatta cgtcacctgg gtgatgggac aaagcaccca tttcgctacg
    27421 ctttttatta gtcttggcgt ggtcggtatg atgatcggca gtatgctggc aaaagtctta
    27481 accgatcgct ggtgtaaatt gaaggtattt ttctggacca atatcgcgct ggcgattttc
    27541 tcctgcgcgt tctatttctt tgacccgaaa gccaccgtga tgatagtggc gctctacttc
    27601 ttgctcaata ttctgcatca gatcccttcc ccgttacact ggtcgctgat ggcggacgtc
    27661 gatgattacg gcgaatggaa aaccggcaaa cgcattaccg gtattagctt ctccggtaat
    27721 ctgttcttcc tgaaactggg cctggcgatt gccggggcga tggtcggctt tttgctctcc
    27781 tggtacggtt atgacgccag cgccaaagcg caaagcgcct cggcgatgaa cggtattatg
    27841 ctgttgttta ccgttatccc tggcgttggc tatctgatta ccgcaggcgt ggtacgtctg
    27901 ctgaaagttg accgtgaact gatgaaaaaa atccaggacg atttggaaaa acgtcgcact
    27961 aattaccgcg aattgagtga gttgcaggag ctcaaagccg ctgaaagcgt aaggaaagcc
    28021 tgatggcaaa ctggccaaac ccgtttattg aacaacgtgc cgatccgttt attttacgcg
    28081 acggcagcga ttactacttt attgcctccg taccggaata tgacaggctg gaaatccgcc
    28141 gggctgattc gctggaaggg ttgcgcgccg ccgaccccgt tgtcgtctgg cgcaaaccgg
    28201 aaagcggccc gatgagccag ctcatctggg caccggaaat gcaccgcatc aacggtaagt
    28261 ggtacatcta ttttgccgct acccatactc aagcgcttga taaactggga atgttccagc
    28321 accgcatgtt tgccctggag tgcgccgatg ccgacccact caccggcaag tggacggaga
    28381 agggtcaaat taaaacgccg tttgatacct tctccctcga tgccaccact ttttatcatc
    28441 agggaaaaca gtggtatctg tgggcgcaaa aagcgccgga tattgccggt aactcaaata
    28501 tttatctggc tgaactggaa aatccgtgga cccttaaagg cgagccggta agactcagta
    28561 agccagagta cgactgggaa tgtcggggtt tttgggttaa cgaaggtccg gccgtcgtgg
    28621 tgcatggcga caagctgttt atcagctatt cggccagcgc caccgatgaa aactactgta
    28681 tggggttact gtggattaac gtaaacgacg atccgcgcga tccggccaac tggcataaat
    28741 caccgcgccc ggtctttacc accagctatg aaaatcgcca gtatgggccg ggacacaaca
    28801 gctttacgca aacgtcggaa ggtgaagatg tactggtgta ccacgcgaga aattacaccg
    28861 aaattgaagg cgatccgttg tacgatccca accgccatac gcgtctgaaa cgggtgcgct
    28921 gggacgaaaa cgggatgcct gattttggcg tgccgccagc cgatacgatc taagccgttg
    28981 cactgcccgg tggcgctagc gcttaccggg cctacagatt tttccattgt aggcagcata
    29041 agcgttagcg ctatcggcac aacattacac taatgcccca taaatggtga gcaacgcaat
    29101 aatcaccacc accacaaacg aggccttctt cgccatcgat accgccgctt tgggggtttc
    29161 tactttgtca gtatgcggtt cgcgcaccag tgagaactgc gccagacgtg tgagcacctg
    29221 atattgcgaa gtatgcagat ccgccagcga ggcaaaccag gccggcaacg ctttctcgcc
    29281 atgccccagt aatgcataca ctacgcccgc cagacgtacc ggaatccagt ccagtacatg
    29341 aagaatagcg tcaatgccgg attgcaaacg ttggtgcggc gtctgatagc gcgccagcca
    29401 ggtctgccag gcccgtaaaa acgcatagcc caccagcgtt accggccccc acggaccgcc
    29461 aacgataaac caaaatagcg gtgcgaggta aaaacggaaa tttatccata acaacgcgtt
    29521 ttgcagctca cgcaaaaact cacgctcatt acaatccggc ggcacgccgt gaatcagcgt
    29581 aagctcgctg gccatcgcct cgcaaggatg cggatcgtta cgggacgccg ctttcagcca
    29641 ggcgtgataa tgtactcgca ctttgcccgc gccgatacac agcacgccca ggagaatcca
    29701 caccaccagc gtcggcacgt taaatagcag cccttttaac gcctggagca gtagaaaagt
    29761 caccaccatc gcgatcgccg tcattcccat cgtgcgcaac atcgaaaaat gcgtaatccg
    29821 acggaatagc gcctccagcc gatgatcgag ctgccagtgc tcgcccagct taaacaggcg
    29881 ctcgacaatc agcaccagta atgtcgtaaa cagcgtcatg tcatctcctt gtgcgacgag
    29941 agggctacca aagcgcgaaa gcgcggccag tcaaaggcag ggccagggtc cgttttgcgg
    30001 tcaggcgcaa tgttgcagtg tccggtcata ttgtcggcga tcgccggata gcaagcgata
    30061 agcgtgcgcg tcacggcggc tagctgctga tactgcgcat cggtataagc cagcgtatcc
    30121 gtcccctcca gctcaatacc aatggagaaa tcattacaac gttcccgccc ctgatagttt
    30181 gatacgcccg catgccacgc acgcttatca aaaggcacat actggacgat ttcaccgtcg
    30241 cgacgaatca gacaatgggc cgaaacacga agatgagcga tttctgcaaa aaaaggatgg
    30301 gcgtctggat ctatcgttcc ggtgaataat gcatcgatcc acggaccgcc aaactcgccg
    30361 gggggcaggc taatattatg caccaccagc aaggacggtt tttcgtcatc cggacggcaa
    30421 tcataatgcg gagaagggac gcgtcgcgcc tctaccaacc aacccttatc tggcaacatg
    30481 cggagtctcc ttttgagtgg tgcttatagc tgcttcagag tagcatgttt ctaccttatg
    30541 attcgttagc aatttggagt tttatcatgc cgcctcgccg ttataaccca gacgaccgac
    30601 gtgacgcgct actggaacgc attaatctcg atatccctgc cgccgttgct caggcgctgc
    30661 gtgaagattt aggtggagaa gtcgatgctg gcaacgatat caccgcgcaa cttttgccgg
    30721 cagatacgca agcccatgcc acagtgatca ctcgtgaaga cggcgttttc tgcggcaagc
    30781 gctgggttga agaggtcttc atccaactgg cgggcgatga tgtgcgcctc acctggcatg
    30841 tcgatgacgg cgacgccatt cacgccaacc aaacagtgtt tgaactgaac ggccccgctc
    30901 gcgtattgct gaccggcgag cgcacggcgc taaactttgt ccagaccctt tccggcgtcg
    30961 ccagtgaagt acgccgctac gttggactat tggctggcac ccaaacccag ttgctcgaca
    31021 cgcgtaaaac gctgccgggt ctgcgcaccg cgctcaaata tgcggtttta tgcggcggcg
    31081 gcgccaatca tcgtctgggt ctcactgacg cgttcctgat taaagaaaac catatcatcg
    31141 cctccggttc ggttcgtcag gcggtggaaa aagcgttctg gctacatccg gacgtgccgg
    31201 tagaagtcga ggtcgaaaat ctggatgaac tggacgatgc gctgaaagca ggcgcggata
    31261 tcatcatgct ggataatttc aacaccgacc agatgcgcga ggcggtgaaa cacgtcaacg
    31321 gccaggcgcg gctggaagta tccggcaacg tcaccgcgga aaccttacgc gaatttgctg
    31381 aaaccggggt ggatttcatc tccgttggcg cgctgaccaa gcacgtgcgc gcgctcgatc
    31441 tctccatgcg tttttgctga tcctctccgc ccgatggcgc tgcgccgtcg ggtctataaa
    31501 tcacctgtcc gtagatccgc gtcgtgattc ggtaaaatat tcgtagcgcc tcgcaataac
    31561 gttgccgtgt catgtaacgc agcgaaaatc ttcagaatcc gccttcccgt tttacctttt
    31621 gccgctcgcc cgctcttccc ttgtttgcca cagtagcgcc ggctaactca aggagcgaac
    31681 aatggaaaaa caacgcggtt tcacgcttat cgaactgatg gtcgttattg gcatcatcgc
    31741 cattttaagc gccattggca ttccggctta ccagaactat ctgcgtaaag cggcgctgac
    31801 ggatatgttg caaacatttg tcccctaccg tactgccgtc gaactctgcg ctctggaaca
    31861 tggtgggacg agcacatgcg atgcgggcgt caacggtatc ccctcgcccg tcatcacccg
    31921 ttatgtttcg ggcatgagcg tggaaaaagg cgtcatcacg cttaccggtc aggagagtct
    31981 gagcgggctt agcgtcatca tgacgcccgc ctgggacaat gctaacggca ttaccggctg
    32041 gacgcgtaac tgcaatattc aaagcgacag cgcgttacaa caggcttgtg aagatgtctt
    32101 ccgttttgac gccaactaag gagacaagat gaaagacgct cagctcaaca ccttgtgtca
    32161 acgtcatcag gctgtactga tcaatagcgc cagcaacagt atcactgttg cggtggtcga
    32221 cgcgccctct catgcgttat tggacgctct gcatttcgcc acgcaaaaac agattgatat
    32281 tgtgtgctgg actcgccagc aaatggaaaa tcatcggcat aagccggatc aggcaccctc
    32341 gacaaacgcc gcgaaaggcg gagaaaccgc ggcccagctt ctcaatcaga cattacgctc
    32401 ggcgatggcg aaacgcgcct ctgatatcca tctcgaaccc ggcgccagcc gctaccggat
    32461 aaggctccgc atcgatggcg ttcttcatat tctgcaggac atcgccaaag agacggggct
    32521 tgcgctgacg gccagattga aagtcctagg aaatttggac atcgctgaac atcggctgcc
    32581 gcaggacggg caatttaccg ttgacctgac gggcgacagc atctcttttc gtatcgccac
    32641 gcttccctgt aaagaaggcg aaaaagtcgt cttacggttg ttgcatcagg ttgaacaaac
    32701 gctggatctg gacacgctgg gcatgtacgg ggcacaactt accgctttta gacaagccct
    32761 acagcaacct caggggctgg tactggtgac tggccccacc ggtagcggaa aaacggtcac
    32821 gctatacagc gcgctacaaa cccggaatac gccgggtatc aacctctgta gcgttgagga
    32881 tccgatagaa attccactgg atgggattaa ccagacgcag atccatcccc gcgccgggct
    32941 cacctttcaa aatgtgctgc gcgcgctttt acgccaggac cctgacatca tcatggtagg
    33001 tgaaattcgt gacggcgaca ccgcagaaat cgccattaag gcggcacaaa cgggccatct
    33061 ggtactttca acactccata cgaactccac cagcgaaacc ctgatacgtt tgcagcaaat
    33121 aggcgtaaca cgctggatga tctcatcggc gcttacgctg gtggtagcgc aacgcctggt
    33181 aaggaagctt tgcccgcact gcaaacagcg tctgagcgat cccgtggtgc tatcgcccaa
    33241 tctttggccc agcgcgctac cgcgctggca ggcaaacggc tgtcagcatt gctaccacgg
    33301 cttttatggc cgaaccgcgt tattcgaagt gttaaccgtt accccggcat tacgtcagtt
    33361 aattgcgagc ggcgcatcgg cgcaagcact ggaagcccac ctccagcaga ccggtacagg
    33421 gacgcttttt gaaaatggct gtcgcgccgt tgagcaaggc atgacgtcct ttgaagagat
    33481 actgcgcgtt ctgggaatgc cccatgagcg ttaaacagct ctggcgctgg caaggcgtta
    33541 acgataaagg tcaactggaa caagacgttg tatgggtgga caatcgtctg gcgctgatca
    33601 tcaccctgca acatcagcgc attatgccgc ttcgcatcaa gcgcataagc gttaacgccg
    33661 cactgtggaa agaagagcaa agcgctgaaa ttattcatca gttggccacg ctcattcatg
    33721 ccggactgac gctttctgaa gggctggaac tccttgcgaa acagcatccc caccgacaat
    33781 ggcaagcgct gttgcgcacg ctggctcacg agcttgaaca gggcgtccct ttttccagcg
    33841 cattagtctc ctggccgcag gtatttccgc cgctctacca gacgatgatc cgcaccggag
    33901 aactgaccgg caaactggcc gaatgctgct ttgaactggc ccgtcagcaa aaagcgcaac
    33961 ggcagattac ggttagcgtg aaaaaggcgc tgcgctatcc cgccattatt ctaacaatgg
    34021 ccgccctggt cgttttcgcc atgctgcact ttgtcctgcc ggaatttgcc gccatttacc
    34081 gtagcttcaa taccccgctt cctcttctga cacgcggtat tatcgcgata gcgcaatggg
    34141 ggccggcatg gggttggctc atcttgttcc tgacgatgct cgttgctatc gctcaccgca
    34201 ggttaaaaca aaaaccgtcc tggcaagcgc agcggcagcg tcttctgcta cggcttcccg
    34261 ttatgggtcg cctgataaga ggccagaaac tagcgcaaat attcaccgta ctggcattaa
    34321 cccaaagcgc aggcattcct tttcttcagg gactggaaag cgctatcgat agtctcggct
    34381 gcccttactg gtcacagcgt ttaacgcagg tacatcagga gatcgccgcg ggcaatccgg
    34441 tctggttggc gctaaaaaat acccaggaat ttagtccgct atgcctgcaa ctggtcagaa
    34501 cgggcgaagc gtccggttca ctcgatatca tgctgcataa ccttgcccgt caccacagtg
    34561 aatctacgct ggcgctggcc gataatctgg cgtcgctgtt ggaaccggcg ttattgatca
    34621 tcaccggctt aattatcggt acgctggtgg tggcgatgta tttgccgatt tttcatttgg
    34681 gagacgcgat gagcgggatg ggataaggct ggcgcacatt tacgccagcc agaatattag
    34741 aggctattga aaatgcggtt ttcttgttcc tgcacccgaa taaaggtggt gcgtttggtc
    34801 aactctttca ggcgagacgc gccgacataa gtgcaggctg agcgtagacc gcccaggata
    34861 tcgcgggcgg tattgcccac cggcccacgc agtggcaatt taaccgtttt accttctgcc
    34921 gcgcggtatt tcgcaacgcc gccgacatga cggttcatcg cagattccga actcatgccg
    34981 tagaacagca tgaatttctc gccattctct tctaccacgc tgccgccgct ctcttcgtga
    35041 cccgccagca taccgcccaa cataacgaaa tccgcgccgc cgccgaaggc ttttgctacg
    35101 tcgcctggca tggtgcagcc gccatcgctg acgatcatgc cgcccaggcc atgcgccgcg
    35161 tcagcacatt cgataaccgc cgacagttgc ggataaccga cgccggtttt tacacgcgtc
    35221 gtgcatacgg agccgggacc aattcccact ttcacgatat cggcgccgga gaggataagc
    35281 tcttcgcaca tctcgcccgt taccacattg cctgcgcaga ttgtttttga cggccatgct
    35341 tcacgcgctt ttgcgacgaa ctgcacaaaa tgttctgaat agccattggc cacatcaata
    35401 cagacaaagt tcagcgcagg attcagcgcc agaatctgca cggttttttc gaaatcagca
    35461 tcagaggtcc cggtggaaac catcacatgc ttgagaacat cagccgaagc cgtgttgata
    35521 aaagctgccc actcttcaac gctataatgt ttatgtacag cggtcagaat atcaaacccg
    35581 gccaacgctt gcgccatttc aaacgtcccg acggtatcca tattggccgc gataatcggt
    35641 acgccagacc aggtctgacc tgagtgttta aaggtgaatt gacgttccag ttcgacatcg
    35701 gaacggcttt tgagggtaga acgcttagga cggataagaa cgtctttgaa acctaacttc
    35761 agatcttctt caatacgcat gtgcggattc ctgaggttaa tggcgaaaaa tcgaaactca
    35821 caactccagt gacgctatca tacgcactaa tcatggccgt acaagactca gaaattctct
    35881 ttttttacgt tacaatccca taaatttacc tggcgaatag taggttaatg ctcagagcat
    35941 atcgtctttg tatgtttaaa atttaacctt ttgattatca aactaaaatt ccggaagctg
    36001 gagatatgag gtataccgta gccttaaccg gcggtattgg cagcggtaaa agtaccgtcg
    36061 ctgatgcctt cgctgacctc ggaataaccg tcatcgacgc ggatattatc gcgcgccaga
    36121 tggttgagcc agggcagccc gccctgaacg caatagcgga acattttggt tctgaactta
    36181 tcgccgccga cggcacgtta cgtcgccggg cactgcgtga gcgtattttt tcgcatccgg
    36241 aagaaaaagc ctggcttaac gctctgcttc atcccttaat tcagcaggaa acccaacgac
    36301 agtttcaaca ggctacgtcg ccctatgtgt tatgggttgt gcctctgctg gttgaaaaca
    36361 ggttgtatca aaaagccaac cgcgtactgg tggttgacgt tacgcccgaa acgcagctca
    36421 tacgcacaat gcagcgtgat gatgttacgc gcgagcatgt tgaacacatt ctcgctgcgc
    36481 aggcgacgcg tgaagcgcgc cttgccgtgg cggacgatgt tattgataat aacggcgcac
    36541 cggatgctat cgcatcagat gtggcccgcc tgcacgccag ttatcttaag ctcgcgtcgc
    36601 agtttgtctc acaggaaaaa ccgtaatgca cacccaggtc ctatttgaac accctctcaa
    36661 tgagaagatg cgtacgtggc tgcgcataga gtttttgatc caacagctct ccatcaacct
    36721 gccaattgca gaccatgctg gcgcactgca ttttttccgt aatatcagcg atctactgga
    36781 tgtgttcgaa cggggcgaag tccgtaccga actgctgaaa gaactggagc gccagcagcg
    36841 taaattacag gcctgggttg aggttcccgg cgtcgatcaa gaccgtattg aagccctgcg
    36901 ccagcagtta aaatcggcgg gcagcgtgct gatctccgcc ccgaggattg gccagcagct
    36961 acgcgaagat cgcttgattg ctcttgtgcg tcaacgctta agtattcctg gcggctgttg
    37021 cagtttcgat ttacccactc tgcatatctg gttgcaccta caacaggcgc agcgcgatgc
    37081 ccagattgaa agctggcttg ccagcctgaa tcccctcacc caggcgctga cgctggtgct
    37141 tgatctgatc cgtaattcag cgcctttccg taagcaaacc agcctgaacg gtttttatca
    37201 ggataacggg gacgacgccg atttgctgcg tcttatgctg acgctcgatt cacaacttta
    37261 tccgcaaatt tccggccata agagccgttt tgccattcgc tttatgccgc tggatagtga
    37321 aaatggtctg gtgccggagc gtcttgattt tgaactggcc tgttgctaag gagtaaaaat
    37381 gtctgacgtg accgtcgtaa actgtccgac ctgcggtaaa ccggtcgtct ggggggaaat
    37441 tagccccttc cgcccatttt gttctaaacg ctgtcagtta attgatttgg gcgaatgggc
    37501 cgccgaagag aaacgaatcg ccagcagcgg cgaccagtct gatagcgacg actggagcga
    37561 agagcgctaa cggtgatagc tctgttgaga cggcaatatc gccttatgac aaaaataatc
    37621 aataaatacg cgtagttttg gcgccatatg cgcgcggccg ggataataca aataaaaccg
    37681 gtccgccgca ggcagccact cctcaagtac ggaacacaac cgcccatcct gtaagtcttc
    37741 gtggacatcc tgttcaaaaa cgtaggttag ctctgcccca tcacgcgcgg cggagagacg
    37801 caacgcttta tcattcacca ttaacgcggc ttccggcgta atttccagcc gttgcgctcc
    37861 atgaacaaac tcccaccgat atagcccgct ctcacgcgta aaacgatggc aaaggcagcg
    37921 gtgattgatg agctcctgag gatgcagcgg cgtgccaaaa cgcgcaaggt atgcagggga
    37981 tgctacgatc gccgggcgta aaacatcacc gagcggaacg acattcatat caagttgtac
    38041 cgcatcgcca aagcgaatac cggcatcaaa gcgttcgtta attaaatcca caaaaccgtc
    38101 attcacatcg atatccagcc gaatatcggg ataatcgcgc atgaagccgg cgagattagg
    38161 ttgtaacaga agcgtggccg ccgtgcgcgg tacggtcagg cgtaatgtcc ctccgggtat
    38221 atcgcggctc tggcaggcat gttccatcgc ctcatcaata tggttcaatg cgggtctgat
    38281 actggcaaga aaggcatgtc ctgcttctgt caaaccgaca cgccgggtgg ttcggttcaa
    38341 taatttcacg ccaagttcat cctccagttg acgcatattc tgacttaacg ccgacgtgga
    38401 aatatgtaac tgcgccgctg cccgcgtgaa gctatggttt tcagcaatca tgcaaaaagc
    38461 atgcaatacg gacatcacat catgacgcat tattaagcca gccttcataa accatgctta
    38521 ttccccctat ttttcatctt atacgccagg tatagactgc ctgccatgca caaaatatcc
    38581 tcatggaggc agtatgcaat atcgtacatt aggcgcaaac ggaccgcgag tgtcagccat
    38641 cggactggga tgtatgggca tgagcgcatt ttacggcgct catgacgaca gcacctcaat
    38701 taagacgcta cattatgcgt tagatcaggg ggtaacactg ctcgataccg cagatatgta
    38761 tggcccttat accaatgaaa ggttagtcgg aagagccatc gccgatcgtc gcgatcgggt
    38821 atttttagcg acgaaatttg gtatcgttct cgaccctgct aaccctatgg cgcgtggcgt
    38881 caatggcaga ccggagtacg ttcgccgtag ttgtgagcaa agcctgcaac gcctgggggt
    38941 cgatcatatc gatctgtact atcaacatcg cgttgatcca tcagttccca tagaagagac
    39001 tgtcggtgca atggcggacc tggtgcgcga gggaaaagtg cgttatctcg ggctatccga
    39061 agcatcaacg caaacgctgg aacgcgccca taacgttcac cctattaccg cgctgcaaag
    39121 tgagtattcg ctttggtccc gcgaagcgga aatttcagca ctttccacct gtgaacggtt
    39181 gggtatagga ttcgtcgctt acagcccgct gggacgcgga tttctgaccg gtacgattaa
    39241 aacgccagaa gattttgctg cgaatgactt ccgtcgcaca aatcccagat tcatgggtga
    39301 gaacttctcg cgcaatttac gtctggctga agcaataaaa caaatggcac gcgaaaaaga
    39361 gtgtaccccc gcacaattag cgctggcctg gctgctggcc cgcaacaggc acctcgttcc
    39421 cattcccggc acccgccact gcgccagggt ggatgaaaac ctcggcgcgt tatcactgac
    39481 cctaagcccg caggagctgg cggcaattga ggcggttttt cctcacgacg ccgcagccgg
    39541 cccccgctac tggccggaaa ttatgtcgac attaaatcgc taataagatc gatggggatc
    39601 gtgttgcgat cccccactaa ggcgcaaatt ggcgtaattt acgaataatc ggttcattgg
    39661 ccggcggaaa atcgtccgta ttcaacgcgt tttgcgcgat ccaccgtccc ggctgtcctt
    39721 ctttccccca cggttcgccc tcccagcgtt caaccagcca aaaccacagc gtaatgtgtc
    39781 tatccgggaa ttgatattcc agagtgtcga ataatgtcac ctgtgttggc gtaatcccca
    39841 cctcttcctg tagctcccgg atcaacgcct gctctggtgt ttcgccggct tcaatttttc
    39901 cgccgggaaa ttccagcttg ttcgccatat gcgcatcagc ggcgcgtcgg gtaataaaaa
    39961 tttcgtcgtt cgggttgcgg ataatcccaa ccgcgatttg cagttttttc atcttggtgc
    40021 atccataaaa aaggcgcagt cgcctgcgcc tttttatctg tgttcaatgc taggccgaat
    40081 aagcgtagcg cccttcggca ataatgccag caccgaccga cctgatggca acacattatg
    40141 tcttatcagg ccggtaagtt tatcgcatca gctcaggcga ccgtgacact gtttgtattt
    40201 cttaccggaa ccacaagggc aaggatcgtt acgtccaatc ttacgttcgc cggtttgggc
    40261 ggccagatcg gcagccacgg cggcatcgtc atcctgatgg cttagctgct gcatctgcgc
    40321 caagcgctcc gcctcttcgc gacgctgcat ttccatcgct tcgacctctt ccggcatacg
    40381 tacctggact ttgctcaggg tactgatcac ttcatatttc agcgattcca gcatcgcggc
    40441 gaacatagcg aaggattcgc gcttgtattc ctgcttcgga tctttttgcg catagccgcg
    40501 cagatgaata ccctgacgca ggtaatccat cgccgccaaa tgctctttcc acagggaatc
    40561 gagcgtttgc agcatcacgc ctttttcgaa atgacgcatc atttcagcgc caaccacctc
    40621 ttctttacgc tgatacacct cgatggactg cgccaggatg cgctcacgca gcgtctcctc
    40681 atgcagctcc ggctctttat ccagccattc ggcaatcggc atctccaggt cgaagtcgtt
    40741 tttcaggcgt tcctgcaaac ccgggatatc ccacatctct tccagcgact gcggcggaat
    40801 gtaggcgtcg atagtcgcct taaagacatc ttcgcgaatg ctgttaatgg tgtcgctcac
    40861 gtcagacaca tccagcagtt cgttacgctg ggtataaatt gcacggcgct gatcgttcgc
    40921 cacatcatca tattccagca gttgcttacg aatatcgaag ttacggcttt ctactttacg
    40981 ctgcgcgtta gcgatagctt tcgtcaccca cgggtgctca atcgcttcgc ccggcttcat
    41041 tcccagttta cgcatcatac cggagacacg atcggaggcg aaaatacgca tcagcgcatc
    41101 ttccatcgac aggtagaaac gggaagaacc cggatcgccc tggcgaccgg aacggccacg
    41161 cagctggttg tcgatacggc gggattcatg gcgctcggtg ccaatgatat gcaggccgcc
    41221 ggcagccaga accgcgtcat ggcgtacctg ccagtccgct ttaatctgcg caatctgttc
    41281 ttccgtcggc gcttccagcg cagcgacttc cgcctgccag ctaccgccca gcataatatc
    41341 ggtaccacga cccgccatgt tggtagcgat agtgaccgcc gctggataac cagcctgcgc
    41401 aacgatgcct gcttcgttgg cgtggaattt tgcgttcagt acgttatgtt tgatgcccgc
    41461 tttggtcagc tctctggaga ccacttcaga tttctcgata gaaatcgtcc cgaccagcac
    41521 tggctgaccg ttcgcggtac gttctttaat atcttcgata atggcctgga ttttttccgc
    41581 ttcggttatg tagaccagat ccggcaaatc tttacggatc atcggacggt tggtcggaac
    41641 aacgacggtg tccagcttat agatagaact aaattcgaag gcttcagtat ccgccgtacc
    41701 ggtcataccg gccagctttt catacagacg gaagtagttc tggaaggtaa tagacgccag
    41761 cgtctggttt tcattctgaa tttcaacgcc ttctttcgct tctaccgcct ggtgcagacc
    41821 gtcagaccag cgacgcccct gcatggtacg accggtatgt tcatcaacaa tgatgacttc
    41881 gccgtctttc acaatgtaat ccacgtcacg ggtaaacagc gcgtgcgcgc gcagcgcggc
    41941 ggtgacgtga tgcatcaaca taatattgcc aggcgagtag agcgactcgc cttcatccat
    42001 aatgccttct tgcaccagta gctcttcgat cagcaccaga ccgcgttcgg tcaggttaac
    42061 ctggcgcgct ttctcatcaa cggagaagtg gccttcgccc tggaaagtgt cagaatcttc
    42121 tttctcctga cgaatcaggt gcggaatgat tttgttcact tttttgtaca tttccgagct
    42181 atcttccgcc gggccggaaa taatcagcgg cgtacgcgct tcatcgatca ggatggagtc
    42241 aacctcatcc accagcgcat aatgcagttt acgctgcacg cgctcttccg ggctgaacgc
    42301 catgttgtcg cgcaggtagt caaaaccgta ttcgttgtta gtgccgtaag tgatgtcggc
    42361 agcgtaagct tcacgtttgg ctggcgcagg catacctggc aggttgatac caacggacat
    42421 accgaggaat tcgaatagcg gacggttgtt ttcggcgtca cgctgcgcca gatagtcgtt
    42481 cacggtcacc acatgaacgc ctttgccgga cagcgcgttc aggtaggctg gcagggttgc
    42541 ggtcagcgtc ttaccttcac cagtacgcat ttcggcaata caacgatcgt tgagcaccat
    42601 gccacccaat agctgaacgt cgaagtgacg catcccaaag acgcgtttac tggcttcacg
    42661 caccaccgcg aacgcttccg gaatcaggct ctctacgctt tcgccttttc caatacgggc
    42721 gcgaaattcg ttggttttcg ctttcagttc gtcatcggag agtttttcca tctccggttc
    42781 catcgcatta ataaggctga cggccttacg catacgacgc agcgtacgat cgttacggct
    42841 accgaatact ttggttaata atttgattag cataataaag tctcaaatgc cccgcgccgc
    42901 ggagctacaa ataaagtaaa agggtctttt ttcgttagct gagacgttgc ggaccggcgc
    42961 ggataccctg cgcctgactt atccaggccg ggatgctaaa tgcggtttgt ggcgcaaaat
    43021 acgccaggga gaggcggcga acaatcgccg gcggcgtgcc ctcctgcgtg agcatcgcgc
    43081 tgagcgtatt cagtaaggcg atatgatgcg cctgtaatgg cgacggcgcg tcggcaacgg
    43141 gcagcgtttg cggcgccatt gcaaaagaaa ggtggcgaat caccgtgcga atagcgtgct
    43201 gatgccagta atctacggtg aaattgggac gacggttaga ggcttctaac agcgcaagat
    43261 ggctaaagtt aactttagac gcggtgctgg cggtcgtcct tgcaggcgta ttggtttcag
    43321 cggcgttact gagcgcgggc aaaccaaaac tcgccgcgac catccctaat aagagatgcg
    43381 gccagaagta tcgtctgcct aactgtcgcc agcgcgtcag tattccactc acgtcattgc
    43441 cacctgatat gcccctcatg ggcttacgga atcaaaacaa tttgcgcaca aatcttatca
    43501 ttaaagcgta cgcgctacag cagtaatgac gagaagctaa ggtgaaaatc ggctaagaaa
    43561 acagcgaacg cgccgtgttt ccatttaacc ctgtcaaaat ggctgtatta aggaaagcgc
    43621 agataaagga tagtaaaaaa aaaacgacta gctcgcctgg ccggagagag tgccaggtta
    43681 accagtcgaa ttttatacga cagcgtatgt cgttatgcca gtaccgtcga aggcgctttg
    43741 aaagccaacg gcagttctgc gtcgtcctgg aaggtcacaa attcccaggc ttcctgtttt
    43801 gccaggactg cctgtaacaa tttgttattc aatgcgtgac cggatttata cgcggtaaac
    43861 gcaccaataa tattgtgacc acacatgaac aagtcaccga tcgcgtcgag cattttgtga
    43921 cgaacgaatt catcttcaaa acgcaggccg tcttcgttca atacgcgata atcgtcaaca
    43981 acgatggcac aatcgaagct gccgcccagg cacaggccgc gggactgcag atattcgata
    44041 tcacgcataa aaccgaaggt acgcgcacgg ctgatctggc gcatgaacgc atccgcagag
    44101 aagttcatcg cgtagcgctg gctgctggaa tcgatcgccg gatggttaaa gtcgatggtg
    44161 aaatccaacg taaaaccatt gtacggtctg aattcagccc atttatcgcc atcttcaacc
    44221 cgaacagtct ctttgatgcg tacgaatttt ttggcgcagt tcagtgcatc aataccggca
    44281 tcaagcagca ggtagacaaa cggagcggca ctgccatcca tgatcgggat ttccggggca
    44341 ttaacctcaa taacgatgtt atcgatacct aagcccgcca gagcagcgtt caggtgctca
    44401 acggttgaaa tccgtacatc atgctcattc accagacacg tacagagcat ggtatcacgc
    44461 acagatttgg catcggccgg gaaatctacc ggtggattca agtcggtgcg acgatagatg
    44521 accccggtat tggccggcgc agggcgtaat gtcagggtga cttttttgcc ggtgtgtaaa
    44581 ccgacgccag tcgcctgaac gatacgttta agtgtccttt gtttgatcat cgtataatct
    44641 cgccaaatta cctatccaac cgaagtgtac tatacattcg gcgggccagt ttagcacaaa
    44701 gagcccagaa tcccaaattc cagctaattc ttaatcagct tgcttacgca ggaatgcggg
    44761 gatatccaga taatccggct ctttcgccgc ctgtggcgca ttgtcgttaa ccactttcgc
    44821 gaccgttttt tgctcctgcg tcagcggcgc cataccgtgc tgctgataac gatccaacac
    44881 cggctgctgc acctgtttat tggtgaccag agtgatttca ggacgcttgt ccataccaat
    44941 tccagtggca acaacggtca cgcgcagttc gtcgttcata tccgggtcca gagaggtacc
    45001 gataaccacg gtggcgttat ccgacgcaaa ggcacggatg gtgttaccga cggtttcgaa
    45061 ctcatccaga cgcaggtcga agcccgccgt aatgttgacc aacacgccgc gcgcgccgga
    45121 caggtcgata tcttccagca gcggagaaga aatagccatt tcagccgctt cttccgcacg
    45181 gtcttcaccg ctcgccacgc cggagcccat cattgcgtag cccatttcag acatcacggt
    45241 acgcacgtca gcaaagtcga cgttcatcag gcccgggcgg gtgatcagct ctgcgatacc
    45301 ctgaaccgcg cctttcagca cgtcgttagc cgcgccgaac gcgtcgagca gggagatgcc
    45361 acggcccagc actttcagca gcttgtcgtt cgggatggtg atcaacgagt ccacatgctt
    45421 ggacagctcg gtgataccct gctccgcaaa tgccatgcgc tttttgcctt caaaattgaa
    45481 aggcttagtc accacggcaa cggtcagaat acctaaatct tttgccactt cagcaaccac
    45541 tggcgccgcg ccggttccgg taccgccgcc catgcctgcc gcgataaata ccatgtctgc
    45601 gccttcaagc gccgcacgca gcgcttcacg gtcttcgtcc gccgcattac ggccgacttc
    45661 cgggttagcg ccggcgccca gacctttggt aatgccgcta ccaatttgaa tggtctggcc
    45721 aaccgccgtc ttacgcaacg cctgcgcgtc ggtattcacc gcgaagaatt caacaccttc
    45781 gatgcgctcg cgcaccatgt gttcaacagc gttaccgccg ccaccaccga cgccgatgac
    45841 tgtaatcacc gcgtcgttgg ttagttccat aggttcaaac ataatctctc tccgtcatgt
    45901 gcctgtcgcc tgaggccgta atatctggcg gcctcataaa aattaaaact cttttcgcag
    45961 ccagctatta agtcgcttga tccacgagcc aactgatgcc gtaacacgtt tttccacttc
    46021 tgcttcaccg tttaagtggg actctttccc gtagtgaagc aatcccaccg ccgttgagta
    46081 atacggctcc tgggcataat ccgtcagacc ggtgatattc agcggcgcgc cgatacgcac
    46141 ctgcgtatga aacacgcgct gagcgcaagc agcaagccct tcgatttgcg ccgcgccgcc
    46201 ggttaacaca atgcccgccg ccaggtgatg ttttacccct tgttggcgaa gctgttcctg
    46261 taattgcaat atctcttcgt tgaccagatt gagcagctcg gtgtaacgcg gctcaatcac
    46321 ttccgccagc gtctgacgtt gcaggctgcg cggcggacgc ccgcctacgc tcggtacttc
    46381 aacgctttcg tctttaccga caatggaacc cagcgcgcaa ccgtggcgaa ctttaatggc
    46441 ttcagcatcg ctcggcggcg taccaaaggc ataagcgata tcgctggtca ccacgttccc
    46501 cgcgtaaggg atcactttgg tatgacgcag cgcgccgcca gtataaacgg cgatatccat
    46561 tgtaccaccg ccgatatcca cgacacagac gcccagttca cgttcatctt ccgttaacac
    46621 ggaataactg gccgccagtc cggcaaatat cagttggtca actttcagac cacaacgttc
    46681 aacagctttg acaatgtttt ttgccatatc gttgtggcag gtaatcaaat gtactttcgc
    46741 ctgcatacgc acgccggaaa gaccgaccgg atttttaatg ccttcctggt agtcaatggc
    46801 gtactcctga ggaatcacat gcagcacgcg atgttcatcg cgcacgcgca ctgacttcgc
    46861 agtatgcacg acgttttcca catcttcctg cgtcacttcc tcttcggaaa tgggcaccat
    46921 accaatttca ttctgacagc taatatgttt gccggaaagc gccagatata ccgaggagat
    46981 ctggcaatca gccatcaatt ccgcctggtc aatggcgcgc tgaacgcatt tcaccactga
    47041 ctcaaggtca ttcaccccgc ctttatccat accccgcgat gggcaactgc ccacgccaat
    47101 gatattgacc ataccgtcgg gcagaacttc ccctactaaa gcggcaacct tcgcggtgcc
    47161 aatctccagt cctactacca gttttctgtc cgtcgccttg atcattgttg ttctgcctgt
    47221 gcctgattct gttgctgatt agattcctca ggggggagcg gcgcccagcc aactgccgca
    47281 cctgagtcat aacgcaaatc aacgtagcta atccgtttgc catcggtttg cgcctgctgc
    47341 tgtaaaaccg gatagagttc tacaaagcga gccaaccttt tcatcgtatc gcccctgccg
    47401 agattgagct taatgccgtt attaagcgtc aattgccagg agcgacgtgc ggtcatcgcc
    47461 gcttccttta gagtgaattt atccttagcc agcacctgcc ccatctcgcg gtatccctgc
    47521 aacacttcac tcgcgctgcc ttccgggccg tacaacatgg gtaaaacctg tttgccgatg
    47581 cggtctgacg gcacgctgaa ggtgttccct tcagcatcga ccatatgttg atcattccaa
    47641 cgcgcaatcg gcacatattc aaccagatga atcttcaatt catcaggcca ctgttttctg
    47701 acgctggcct gtttaatcca cggcaaacgc tcaatctggc tctggataat gttcacatcc
    47761 tgcgtcatga aggttcccgg cgcgcccaga gccagtatcg cctgacggat atcatcgtta
    47821 cgcgtgtagt gacgctcgcc ggttaatacc agctttgata acggtaaacg ctgcgcatct
    47881 tccatccacc ctaacacgac ccacccgcta acaaacacgg tgcacagtac cgtcagcagg
    47941 aataatattc ctgcaagacg cgttccatta ttgcggcgtg aagaaggcgt ctcttcatca
    48001 ctgtttcgcg tgttcagcgc agcctgcgac atatcagtcc gccaactcca gaattcgtac
    48061 cactaactgc gagaagctca ttcccgcctg acgcgccgcc atcggcacca gactatggct
    48121 ggtcatcccc ggagaagtat tggcttccag cagataaaac tgaccatcgc tgtccagcat
    48181 gacgtcaata cgcccccatc ccgtgcagcc taaagctttc catgcctgca ggacgagaga
    48241 ctgtagcgcg gcttcctggg acgcttctaa accggcaggg cagaaatact gagtctcatc
    48301 agagagatac ttcgcctcat aatcatagaa ggttcctgcc ggttggatac gaattgacgg
    48361 taaaatttct tcgccaacta tcgccaccgt aaattccgga ccgcacagcc atttctcaat
    48421 cagtatttcg tcatcatgct gaaaagccaa tgataacgca ccctgtaaag cattttcttc
    48481 tactactttc gtcataccga cgctggagcc ttcacggctg ggtttgacga tcagcggtaa
    48541 acccagcgcc gaaattcgcg ctttttgttc ttcgctaagg cctttttcaa actcagcgcg
    48601 cgtcagcgcg acccacggcg caaccggtaa gcctgcgccc tgccacagca atttactgcg
    48661 cagtttatcc atggaaagcg ccgaggccat cacgccgctg ccggtataag gcaggccgag
    48721 cagttcaagc attccctgta aggtgccatc ttcaccgccg cggccatgca acgcaataaa
    48781 gaccttctga aagcccattg ctttaagctg cgcgacatcg acctcttgcg gatcgacggg
    48841 atgcgcatca ataccgcctt cacgtaaccc ggccaacact gccgcgccgg aatttaacga
    48901 aacgtcccgc tccgcagagg ttccgcccaa caggaccgcg attttatcag ccatgttgct
    48961 cttcctcctg gatttgcggc ttcagcttga tttcagataa gtaacgcgca attttgccaa
    49021 catttcctgc gccttgcact aatatcaagt cgttacccgt cagcaccggc gctaacattg
    49081 tcgcaacctg agccggatcg gaaaccagaa tcgggtcaat ttttccccga ttacgaatcg
    49141 tgcgacataa agaacggcta tccgcgcccg gaatcggcgc ttcgcccgcc gggtaaacgt
    49201 ccagcatcag cagcgcatcg acctgggtca gcacattggc gaaatcgtca tacagatcgc
    49261 gcgtgcgcgt gtaacgatgc ggctgaaaca gcatcaccag gtttttatcc ggccaccctg
    49321 ctcgcgcagc tttaatggtg gcgtccactt cggtcggatg atgtccatag tcatccacca
    49381 gcatcgccgt cccggcttta ccattcaccg gctcaagcgg gaactcgccg aggaagtcaa
    49441 aacgacgccc ggtcccctgg aagctttcca gcgcgcgcag gatagcgtca tcgtcgatgc
    49501 cttcttcggt cgctaccgcc actgccgcgg cggcattcag ggcattgtgg cgacccggcg
    49561 cattcaacgt gacatgcaga tccggcattc cctggcgcaa cagcgtaaag tgcccctgcg
    49621 gccctatctg ctgataatct tctacgcgga cgtcagcatc ctcgctaaag ccatacgtcg
    49681 tggtctgacg ccccacccgc ggcagcaact cgcggatgac cggatcgtcg acgcacatta
    49741 ccgcgcgacc gtagaacggc aggttatgca ggaagttaat aaacgtctgc tttaaatttt
    49801 caaagtcgcc atgataggta tccatatggt cggcttcgat gttggtgacg atcgcaacca
    49861 tcggctgcaa atgcaggaag gatgcgtcgc tctcatctgc ctcggcaatc aggtaacgac
    49921 tatggcccag acgcgcatga acgcctgcgg ctttcaccaa tccgccattc acgaaagtcg
    49981 ggtccagccc cgcttcggca taaatactgg acaccatcgc ggtcgttgtg gtttttccgt
    50041 gcgtcccggc aatggcgatg ccgtggcgaa aacgcatcag ttccgccagc atttccgcac
    50101 ggcgaataac cggaatacgc gcttcatgcg ccgcgacaat ttccgggtta tccgcggaaa
    50161 ttgcgctgga aacgacgacc acgctggcat cacgcacatt ttccggacga tggttaaaga
    50221 aaatcgtcgc ccccaggctc gtcaactgct gggtcaccgg attcggcgct aaatcggaac
    50281 cactgatctg atacccttca ttggccagaa cttcggcaat accgcccata ccagcaccac
    50341 cgatgccgac aaagtgaatg tgccgaacgc gacgcatttc gggcacgatg gaacgcagtt
    50401 ttgccagttg ttgtgtattc attctttacg ccattaactc caatacccgc catacttcaa
    50461 attgcagatg cgttggcttg cctgcaaccc aaattattga gggtagaaaa accctgcgat
    50521 gcaaaaggca ccgccacaaa ttatgtccgg gcaacccggc tgacttcact ggcgacgcgc
    50581 tcggtagcat ccggaatgga taccgcgcgg gcacgctccg ccatggttaa caacgcctcg
    50641 cgcgaccacc ccgccagggt gtcggcgaca gcctctacag taaactgcgg ctgctcaaaa
    50701 atcttagctg cgccggcgtt ttctaacggc agcgcattcc agtactgctg cctgtcttta
    50761 tgctgaaacg gcacgaatat cgccggtaac ccggcggcgg cgatctcgct caccgttaaa
    50821 gcgccggaac gacataccac cacatccgcc cacgcatagg cggcggccat gccatcgata
    50881 aattccgtta ccttatgctg cggttgtccc gccccggcat atgcctgctc taccgtgagc
    50941 tgcgcgcctt ttccgctttg atgccagatt gtaaccgtat cgcccagtct ggcggcaacc
    51001 tgcggcatcg tctggttcag gactcgcgcc ccctgagaac cgccgaccac caacacgcga
    51061 atcgggccgt cacgaccggc cagacgcacc tgcggcaacg gcaacgccag tacgtcggta
    51121 cgcaccgggt tacccaccac ttccgcgttc gggaacgcac cgggaaacgc ctgcatcacc
    51181 gtggtcgcga ttttggccag ccactgattg gttagcccgg cgataccgtt ttgctcatgc
    51241 aaaacgaccg gaatacccaa tgaccaggcg gcaagaccgc cggggccgga aacataaccg
    51301 cccattccca gcacgacatc cggcttaaac cgcttcatga tcgcccgcgc ctgccgccag
    51361 gcgttaaaaa tccgcagcgg cgccgccaga agcgctttta cgcctttacc gcgcagaccg
    51421 gagatccgaa taaagtcaat atcgatgcca tgcttcggca ctaaatccgc ttccatacga
    51481 tcggaggtac ccagccagcg aacctgccag ccctgggcca ttaaatgatg cgcaacggcc
    51541 agtccgggga acacgtgccc gccggtaccg cccgccatca ccattaaccg cttcggttga
    51601 ccactcatcg agaacctcgt gtaaacgcct gcgctttttc cagacgcgtt tcataatcaa
    51661 tacgtaataa aaacataatg gccgtcgaca taatcaacag actcgacccg ccataactga
    51721 tcagcggcag cgtaagacct ttggtcggca gcatccccgc ggccgcgcca acgtttacca
    51781 gcgcctgaaa actaaaccag ataccgatag aacacgctaa aaatccggaa aaacggtggt
    51841 caatctccaa tgccttacgg ccaatcgaca tcgcgcgaaa agcgacgaaa aataccatta
    51901 aaagcgccaa taccacaccg atataaccca gttcttcccc aataatggcg aagatgaaat
    51961 cggtgtgcgc ctccggcaaa tactccagtt tctgcaccga attccccagc ccttgccccc
    52021 atatctcacc gcgaccaaaa gccatcagcg actgcgtcag ctgataaccg ctgccgaacg
    52081 gatcttccca ggggttccag aacgaggtaa cgcggcgaat acgatacggt tcggcgagga
    52141 ttaacagaat caccgccgag atgcccatcc cgataatggc gatgaactgc cataatttcg
    52201 ccccggcaag aaacagcatc gccagcgtgg tgacaaacag tacgaccacc gtcccgaggt
    52261 caggctgtgc cagcagtaac accgccagca ccagaatcac gcccattggt tttaaaaagc
    52321 cgcgcaggtt atttcgcact tcatcaacct tacgcaccag atagttcgcg aggtagcaga
    52381 acagcgacag cttggtaaac tccgcaggct gaatacgcag cggccccagc gcaatccagc
    52441 gcgacgcccc gttaaccgag ctcccgacga ccagcacgat aagcagcata atgatcgacg
    52501 caatcagcat cgtcgtgctg tatttttgcc agaaggtcat gggcaaacgt agcgtgacca
    52561 tcgccagaca aaatgccagg aagatataga gcgcatcacg tttggcaaac aaaaacggat
    52621 cgttcgccag gcgctgcccg actggcatgg aggccgacgt caccatgaca aaaccaatcg
    52681 ccgccagccc gaaggtcagc catagcagcg tgcggtcata catgatcaga ctgtcggcgt
    52741 ctttatcgcg cgaagccatc acccagcctt taagcgccgc aaacagccag gccaggaagc
    52801 caaagcctgg tacgcgcggc attctcagac gggggagaga taaacgcatc aacctaactc
    52861 cttcgccaga cgggtaaaga catcgccccg ttgctcaaaa tttttaaact gatcgaggct
    52921 ggcgcaggcg ggcgacaaca gcaccatatc acccggctga acgtgcggcg ccagcaaacg
    52981 catcgcctct tccatcgtct cagtctgttg ggcgatttcc ggacgcagtg cggcaagctg
    53041 cgcgccatcg cgcccaaagc aatacaggcg gatacgatcg ccggtcagat agcgcgccag
    53101 cggagaaaag tctgccgact taccgtcgcc gcccagcagc agatgcagcg taccgtccac
    53161 atgcaaaccg tttagcgccg cttcggtact gccgacattg gtcgctttcg agtcgttgat
    53221 ccaacgaacg ccgttatgct ccaacgccag ctggaagcga tgcgccagac cggtaaatgt
    53281 cgtcaacgcc ttcaaactgc tggcgcgcgg cagacctacg gcatccgcca gcgccagcgc
    53341 cgctaacgca ttggtatagt tatgctgacc ggaaagcttc atctctttca cgttcagcac
    53401 cttctcacct ttgactcgta gccaggtttc gccctgctga cgattaaggt gataatcacc
    53461 catattgacg ccaaagctga cgcagcgctc atcggccccg cgtaccggca tcgtcaacgc
    53521 gtcatcggca ttcactacgc acactttcgc cttctcgtag acgcgcagtt tcgccgcccg
    53581 gtactgttgc aaaccaaacg gataccggtc catatgatct tcagtgacgt tgagcaccgt
    53641 tgccgccgcc gcttgcaaac ttgaggtagt ttccaattgg aaactggata attccagcac
    53701 gtacaattcg cgatcggcat ccagcagcat cagcgccgga agaccgatat tgccgccaac
    53761 gccgacattg acgcccgccg ccttcgccat ctcgcccact aaggtggtca cggtgctttt
    53821 gccgttcgag ccggtgatgg ccacaatcgg cgcttgcgct tcgcggcaaa acagttcgat
    53881 atcgccgaca atttccactc cagcgctggc ggcagcgcta agagagggat gcgccagagc
    53941 aataccaggg ctggcgacga ttaaatccgc cgctaagagc cactcgtcgt tcaggccgcc
    54001 aacgtgacgc tcaacctctt gcggcagctt atccagaccc ggcggcgtca cgcgagtatc
    54061 catcacccgc ggcgtcacgc cgcgggcgag aaaaaagtcc acgcaagaga gtccggttaa
    54121 gcccagaccg ataatgacga cgtttttgtc ctggtaatca gccatgatta acgtaccttc
    54181 agcgttgcca ggccaatcag caccagcatc agcgaaataa tccagaagcg cacaatcacg
    54241 cgcggttccg gccagccttt cagttcatag tggtgatgga taggcgccat acggaaaata
    54301 cgctgtccgc gtagtttaaa ggaacccacc tgcaggatga ccgacagagt ttccaccaca
    54361 aagacgccgc ccatgatcac cagcagaaat tcctgacgca gcagcacggc gataatgccc
    54421 aacgcgccgc ccaacgccag cgatccgaca tcgcccataa aaacctgcgc cggataggtg
    54481 ttaaaccaca agaatcctaa tcccgcgccg acaatcgccg tacagacaat caccagctcg
    54541 cccgcatggc gtaaatacgg aatatgcagg taattggcga agttcatgtt cccggtcgcc
    54601 caagccacca gcgcaaagcc ggcggcaacg aagacagtcg gcataatcgc cagaccatca
    54661 agcccgtcgg tcaggtttac ggcgttaccc gtaccgacga tgacaaagta ggacagcaga
    54721 atgtaaaaca gccccaattg cggcataaca tctttaaaga acggcaccac cagttgggtc
    54781 gcgggcgtgt ctttcccgac gagataaagc gcaaaggcca cgccgagcgc gataaccgac
    54841 atccagaaat atttccagcg cgcaatcagc cctttggtat ctttccgcac cactttgcgg
    54901 tagtcatcga caaaaccgat aatgccgtag ccgatcaata ccaccagcac gcaccagacg
    54961 tacgggttag acgggtaagc ccataacaga acggaaatca caatcgccgt caggatcatg
    55021 atgccgccca tcgtcggcgt accgcgttta ctgaagtgcg attccgggcc atcgttacgt
    55081 accacctggc caaaagagag tttttgcaga cgagcgatca tacgcgggcc catccataaa
    55141 gagatgaaca gcgcggtcaa caggctgacg atggcgcgaa acgtcagata agaaaagacg
    55201 ttaaagccgg aataatattt gaccaaatgc tcggccagcc aaactaacat gaacctttct
    55261 cctgtaacgc atgaaccaca tcttccatcg cggcgctgcg tgatcctttc actaaaatag
    55321 tcatcatcgg ttgctcctga agcagagcgt gtaaacgcgc aatgagcgcg gctttatcgg
    55381 caaaatgttc gccgacgccg ctggcgtggc tgataacctg actgagtttt ccggtgctta
    55441 acacgcgatc aatacccgcc gcttttgcgg cctcgccaac ctggaggtgg cacgcttcgc
    55501 tttctgcgcc cagctcggcc atatcgccta ccaccagcac gcggtagccg ggcatttcag
    55561 aaaggacctg cactgcggcg gtcatcgaac cgacgttggc gttataagcg tcatccagta
    55621 ccagttggtt ttcacttagt tgaatcggga acagacgccc gggtacggct tttaacgccg
    55681 ccagccctgc tttaaccgcc gccagcgtcg cccccaccgc cattgataaa gcagcggccg
    55741 ccagcgcgtt ggcaatattg tgccgccccg gcaacggcag cagcacatca atgctgccca
    55801 tcggcgtttg cagggtaaat tcggtaccgt gtgacgtcac gtggatattc gcagcggtaa
    55861 agtcgctgtt tgccgcattc ggcgaaaagc gccacacctg acgatcgcca ataatgcttt
    55921 gccagttcag ccagtcatta ttatcggcat tcataatcgc gataccgttc tcaggcaaac
    55981 cggtatagat ttcgcctttc gctttcgcca cgccggccag cgagccgaaa ccttccagat
    56041 gcgccgccgc caggttattg accagcgccg cttccgggcg cgtcaggcta acggtccagg
    56101 cgatttctcc ctggtgatta gcgcctaact cgatcaccgc atagtcataa tcatggttta
    56161 agcgcagcag cgttatcggc acgccgatgt cgttgttaaa attgcttgcg gtatacaaag
    56221 tatttccgca ctggctaaga atcgcggcgg tcatctcttt gaccgaggtt ttgccggacg
    56281 aaccggttaa cgccaccacc cgcgccggta cctgcatacg tacccaggcg gccagttggc
    56341 caaatgcctg acgcgtgtct tttacaatca cctgcggaag atcgatatcc agaggacgac
    56401 tgaccagcag ggcgccagcg ccgttcgctt ttgctttatc agcaaaatca tgcgcatcaa
    56461 agcgttcccc tttcagcgcc acgaacaggc atcccggcgt cactttccgt gtgtcggtaa
    56521 tgaccgtatc gagcgtgaga tccgccccgc ggtgttcggc gccaaggaca tcggcaattt
    56581 tgctgagcgt tacgctaatc atgcgatcac ccccagcaaa cgcgctgcgg tcacgcggtc
    56641 tgaataatca agacgctgcg tgccgacaat ctggtaatcc tcgtgccctt tacctgcaat
    56701 cagcacgacg tcattgtctt ttgcctgcat aatggcattg gttaccgcct cagcgcggcc
    56761 ttccattacc ctgacctgcc cggcgtccag cattccggcc agaatatcgt tgataatggc
    56821 gcgcggctcc tcggtacgcg ggttatcgtc agtcaccacg acgatatccg cgaattcttc
    56881 ggcaatggcc cccatgagtg ggcgcttacc tttgtcacga tccccgccac agccaaagac
    56941 gcaccacaat tttccggcgc agtgcaggcg cgccgcctgc aatgcttttt ccagcgcatc
    57001 cggcgtgtgc gcgtaatcca ccaccaccgt cggtttgcct ggcgcagtga acacttccat
    57061 acgcccgcaa accggctgca aacgcgcggc ggttttcagc aaatccgtta acggatagcc
    57121 cagcgccagc agcgtcgcca atgccagcag taagttgctg acgttaaacg cgcccatcag
    57181 gcagctttcg atttcgcctt caccccagct tgaagcaaaa cgaatcgtca ctccgcggtc
    57241 gtggtactcc accgcctccg ctttcagcca acgaccgtga cagttagggt tgatatgccc
    57301 ttccattgaa accgcgaccg catcgggtag cgacgccagc cagcggcgtc caacttcatc
    57361 atcggcgttg acgattgcct gaccgtgatg gtgggtggaa taaagcatcc attttgccgc
    57421 ctcgtaatgc gccatatcgc catgatagtc gagatggtcg cggctcaaat tagtaaacac
    57481 ggaggcggca aatttcagcg ccgccacgcg atgctgcacc aggccgtgag aagagacttc
    57541 catagcgccg aaggtcgcgc cctgcgcaac cagactggcc agcacatgct gaacatccac
    57601 tgcggaaccg gttgtgttct ccgtcgggat cactttaccc aacagtccgt tacctaccgt
    57661 ccccatcact gcgctggttt cgccgagcaa ctggctccac tgcgccagta gttgggtggt
    57721 ggtggtcttg ccattggtgc cggtcaccgc caccagacgc atgttttcag atggctcatg
    57781 gtaaaagcgg cccgccagcg cagataaacg ctcattgagc tggctgagat agacgactgg
    57841 tacgccgtgc atttcgcgaa tctcaccgtc actcgcctcg tctttcgcct ctgcaataat
    57901 ggcagctacg ccttgcgcta tcgcctgcgg gatataacga cgcccgtccg cctgatgacc
    57961 caccactgcc acaaagagat cgcccgccgc agccacacgg ctgtcgagcg tcatctctcg
    58021 cagttctcgc gcgggtagtc cagccaccca cggagcaaga aggtcgcgca aattacgatc
    58081 tgccacctgt tccctcgcct tgattaatta cgaattcatt tttttcgccc gttgccagcg
    58141 cgtccggttc gatgttcatg gtgcgcagaa cgccgcccat gatggcacca aataccggcg
    58201 cggaaacggc gccgccgtag tatttacccg cctgcggatc gttgatgaca accaccagcg
    58261 cgaagcgcgg ctgactcgca ggcgcgacgc ctgcggtgta agcaatgtat ttgttgatgt
    58321 agcgaccgtc cggccccact tttttcgccg taccggtttt aatcgcgata cggtagcctt
    58381 taattgccgc cttcacgccg ccgccgcccg gcagcgccac gctttccatc atatgcacca
    58441 cggtgcgtac ggtggattca gggaagatgc gttcgccggg tacaggcgga tcaactttgg
    58501 taatcgacag cgggcgataa atgccatagc tgccgatcgt tgcataaact cgcgctaact
    58561 gtaacggcgt taccattagc ccgtagccga aagagaaggt ggccctctct atgtcggacc
    58621 accgttgttt ttgaggatat aagccactgc gttctccgac caaccccaaa ttggtcgcct
    58681 ttcctagccc aaaacgtgag taagtatcta ctaacgctga ggacggcatc gctaacgcca
    58741 gtttggatac accgacgtta ctcgacttct gtagaacccc agtcagggtt aattcgctgt
    58801 agcgcgccac gtctttaatt tcgtggccgt taattcggta tggaacggta ttcaacaccg
    58861 tattttcgtt gacgataccg cgctgaagcg cagtcatcac caccatcggc ttaaccgtag
    58921 aacccggttc aaacacgtcg gtgatggtac ggttacgcat cgcgtctttc ggcgtaccgg
    58981 caaggttgtt ggggttatag gaagggctat tcgccatcgc cagtacttca ccggtattga
    59041 catcgaccag caccgcgcta ccggattccg ccttgttaaa cgccaccgcg ttgttcagtt
    59101 cgcggtaaac cagcgcctgt aagcgttcat caatgcttaa cgccaggttg tgcgctgcct
    59161 gactgtcagt ggaggagata tcctcaatca cgcggccata gcggtcttta cgcacgattc
    59221 gctcgccagg ctgaccggta agccacttat caaagctctt ttcaacgcct tcaatcccct
    59281 gactgtcaac gttggtaaaa ccgatgaggt gagcggttac ttctcctgac gggtagtagc
    59341 ggcgtgattc ttcacgcaaa tgaatccccg gcagtttgag ttttttgatg tagtccgcca
    59401 tgtcaggatt tacctggcgc gccagataaa taaaacgccc tttcgggttg gcgttgatac
    59461 gggcggagag ctgatcgagc ggaatattga gcgcagtaga aagcgctttc cagcgatcgc
    59521 cgacgctgat gccgccggcg tcatgaactt ctttcgggtc ggcccagatc gccttaaccg
    59581 gtacgctgac cgccagtgga cgcccggaac ggtcggtaat cataccgcgt gaggtggaga
    59641 cttcctgaac acgcagcgaa cgcatatcgc cctgacgcac cagcatatcc ggggcgataa
    59701 tctgtagcca cgccgcgcgt ccaagtaaaa aaaccagcgc cagtaaaata cagccgcaca
    59761 gcaacgcaaa acgccaactg atgaagttgg tctgttcttc ctggcgcttc gatttttgcg
    59821 tttttgccgc tgctttcatg cgtcgcgttt atccttattt ttgcactacg atattttctt
    59881 gggacggatc aacatgctgc atttgcagct tttccgttgc gatccgctct acccggctgt
    59941 gatcgccgag cgcattttct tcaaggatca ggttgcgcca ttcaatgtcc aatgcatcgc
    60001 gctccagaac cagttgttca cgctgagcgg tgagtaaacg agtatggtgc gccgtcgtga
    60061 ccaccgtcac cgccgttaaa atgatgcaaa tgaacaagca gagtggcagc ttcccgaacc
    60121 gcaaaagatc gtcaccgatc acgccaggca aggcatggcg ctcgttgctt cctatcgatc
    60181 ccttaacttt gcttagggct tctgtcactc tgctgatcat gcgttcgtcc tctctgcgat
    60241 acgcagaact gaactacggg cccgaggatt ttcagctacc tctttttcac ccggcatcaa
    60301 cttgcctaac gctcgtaact cacgaccgcc cagttttttg agctgcgctt ccgtcatcgg
    60361 taatcccgcc ggtacctgcg gaccgcggct ttgctcacgc ataaagcgtt tcacaatacg
    60421 gtcttccagc gagtggaaac tgatgattga aagccgcccg cctgaggcca gtacgctgag
    60481 cgagcttttt agcgcctgct ctatctcctc cagttcactg tttacccaga tgcgcaccgc
    60541 ctggaaggta cgggtcgcgg gatgtttgaa tttgtctttt accggggtcg ccgccgcaac
    60601 cacttccgcc agctctttgg tgcgggtcat cggctgttcg cgattgcgct caacaatggc
    60661 gtgagcaata cgtttggcaa aacgctcctc gccgaatgtt ttcagcaccc aggcgatatc
    60721 cgcctcctcc gccgtttgta accactcggc ggcagactgg ccgcgcgtcg ggtccattcg
    60781 catatccagc ggaccgtcgc gcataaatga aaaaccgcgc tccgcatcgt caagctgcgg
    60841 agaagagacg ccaagatcga gaaggatccc gtcaatcttg ccggtaagct cgcgctcggc
    60901 gacataatca gccagcgcgg aaaaaggtcc atgaatgatg gagaagcgag gatcattaat
    60961 ggtctgcgca acggcgatcg cctgcggatc gcgatcgatc gccagcaagc gcccctcttc
    61021 gcccagttgc gagaggatca ggcgcgagtg gccgccgcga ccaaatgtgc catcaatata
    61081 gataccatcc ggacgaatat tcagcccatt aacggcttca tccaacagta ccgtagtgtg
    61141 tttaaaattt tccatcatct tatagagaca agtcctgcag ccgctccgat aacgtttcgg
    61201 tagctgactg ttcagcgtcg atatcttcct tgacctgttg ataccaggtc gtttcatccc
    61261 acagctcaaa tttgttgaac tgtccaacca gcatcacttc tttcgtcagt ccggcatgtt
    61321 gccgcagaac tggcgcgatc agtaatcgac ctgcaccatc catctgacat tcactggcat
    61381 ggcccaacag taaacgctgt acgcgacgtt ctaccgggtt catgctcgac agacgagata
    61441 acttttgctc aataatttcc cattcaggca gggggtaaag cagcaggcat gggtgatgga
    61501 tgtcaatggt acatactatt tgaccggtag cgctctcgat cagttgctcc cgataacggg
    61561 tcggcacggt caggcgccct ttactgtcga gattgactaa cgttgccccc cggaacatgc
    61621 cagtctcacc ccttcttacc actttatccc acaaattccc actcgaagga gtttacggag
    61681 cggaggaaaa gcttgtcaag caagtcacaa cgcttaccga agtaaaaaag ccaatgttta
    61741 cggcgaatat ctgcgttgat taatttccgc ccagcgcgca agccaaatta acgttatgaa
    61801 tatttgtaag aaaaaaacca aagacccacc gccgtttaaa acggactcaa tataatccga
    61861 gaaaaatata aagtgtcagt ttgcgacgcg agcggcattt taggacatat tgcaccgtgt
    61921 taacagtgcc tgtttaacgt gtgcggcgcc tgctatacca gcgcctacaa gcgactgtcg
    61981 cgccaaagac aaaaagtggc tgttaattcg acgatttctt gcctgcttgt aacaaaacaa
    62041 tacaaaggaa
//
LOCUS       DAJVKX010000006        61466 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000006 DAJVKX010000000
VERSION     DAJVKX010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 61466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61466
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.006"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            375..665
                     /locus_tag="OPY25_000360"
     CDS             375..665
                     /locus_tag="OPY25_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0926078.1"
                     /translation="MKKRIIAAALLATVASFSTLAAEQVSKQEISHFKLVKVGTINVS
                     QSGGQISSPSDLREKLSELADAKGGKYYHIIAAREHGPNFEAVAEVYNDATK"
     gene            complement(889..1305)
                     /locus_tag="OPY25_000361"
     CDS             complement(889..1305)
                     /locus_tag="OPY25_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926079.1"
                     /translation="MKLIPFYLLALFSAASGATEINACKDLIGTWKTTADNPPYTMTI
                     LPPVEGCGEKCVKLNVQYELDVTHRNALYCHEGQEGVKGQGPMVIAFEGAYGGHAIGT
                     YNRQLQLLWAGVIPKNKKGKWITKMENYWFRQVKAH"
     gene            complement(1596..1826)
                     /locus_tag="OPY25_000362"
     CDS             complement(1596..1826)
                     /locus_tag="OPY25_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCS0926080.1"
                     /translation="MQKRLMTALFTAATLFTVAGCSSNQAVETTDGKTIVTDGKPEVD
                     NDTGMVSYKNAATGKTEQINRDQLKNMSELDN"
     gene            complement(1915..3255)
                     /locus_tag="OPY25_000363"
     CDS             complement(1915..3255)
                     /locus_tag="OPY25_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0926081.1"
                     /translation="MPQPRNFDDLKFSSIHRRIMLWGSGGPFLDGYVLVIIGVALEQL
                     TPLLHLDAEWIGALGAATLAGLFIGTSLFGYICDKVGRRKMFLLDIIAIGVISVATMF
                     VSTPLELLVMRVLIGIVIGADYPIATSMITEFSNTRQRAFSIGFIAAMWYVGATCANL
                     VGYWLYDMEGGWRWMLGSAFIPCLIILIGRFDLPESPRWLLRKGRVKECEQMMIKLFG
                     EPVCFDDEPPQETRFLQLFNRRHFPFVLFVAAIWSCQVIPMFAIYTFGPQIVGLLGWE
                     QGRNAALGNVVISLFFMLGCIPAMFWLNSIGRRPLLIGSFAMMTIALALLGLVSNLGI
                     ILVVVAFAVYAFFSGGPGILQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FITRYGINNVMLIGALISLVGLGVSVMFAPETRGLTLTQTGNMTLRGTPSDNPR"
     gene            complement(3403..3690)
                     /gene="fixX"
                     /locus_tag="OPY25_000364"
     CDS             complement(3403..3690)
                     /gene="fixX"
                     /locus_tag="OPY25_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HCS0926082.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEDSPHIILKTDPDKQALEVLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLDTALEKWEYPRGTFGVEFRYG"
     gene            complement(3687..4973)
                     /locus_tag="OPY25_000365"
     CDS             complement(3687..4973)
                     /locus_tag="OPY25_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCS0926083.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLERIIPGFADQAPIERMITHEKLAFMTDNGAMTIDYCNGEDASASQVS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNVVQRDGKVVGVEADGDILEAKVVILAD
                     GVNSLLAEKLGMAKRVEASHVAVGVKELIELPKSVIEDRFQLQGNEGAACLFAGAPTD
                     GLMGGGFLYTNETTLSLGLVCGLHHLKDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     AAHVVPEAGMNMQPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAISAGEAAAKTVLSA
                     MKRDDFSKQSLGEYRQHLDEGPMRDMRMYQKLPAFLDNPRMFTAYPEMAVSIARDLFT
                     VDGSAPVPMRKKILRHAKKVGFINLMKDGLKGVTVL"
     gene            complement(5023..5964)
                     /locus_tag="OPY25_000366"
     CDS             complement(5023..5964)
                     /locus_tag="OPY25_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HCS0926084.1"
                     /translation="MNKFSSVWVFSDTPSRLPELMSGAQAVGEKVNAFVLNEADSATA
                     CHLGADHVWLLSGKPEDRMIEDYAAAMAETIRQHSEGGAVLLPNTRRGKLLAAKLGYR
                     LSAAVSNDASDVSLQDGKAAVKHMVYGGLAIGAETIASPFAVITLSSGTFDAQQPDAS
                     RSGEMHTVQWQAPATAVTRTATQARQSNSVDLDKARLVVSVGRGIGSKENISLAEALC
                     QTIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANGAQT
                     IFAINKDKNAPIFQYADFGIVGDALKILPALTAALAR"
     gene            complement(5980..6750)
                     /locus_tag="OPY25_000367"
     CDS             complement(5980..6750)
                     /locus_tag="OPY25_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HCS0926085.1"
                     /translation="MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEA
                     ACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQHTAT
                     ALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
                     RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPA
                     YSTQQVAAPKQRERQRVVIEGDGEEQIAAFVENLRKII"
     gene            7231..8748
                     /gene="caiT"
                     /locus_tag="OPY25_000368"
     CDS             7231..8748
                     /gene="caiT"
                     /locus_tag="OPY25_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HCS0926086.1"
                     /translation="MKNEKRKSGIEPKVFFPLLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDEKPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKEIGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMDVIRPSSTLVPLVGEKHAKGLFSTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMHLPRMLFYTDAIGKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLMDKNILNIPQLIEQHGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLINACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKVHWKDK"
     gene            8783..9925
                     /gene="caiA"
                     /locus_tag="OPY25_000369"
     CDS             8783..9925
                     /gene="caiA"
                     /locus_tag="OPY25_000369"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HCS0926087.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCTFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQ
                     VLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            10037..11254
                     /gene="caiB"
                     /locus_tag="OPY25_000370"
     CDS             10037..11254
                     /gene="caiB"
                     /locus_tag="OPY25_000370"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HCS0926088.1"
                     /translation="MNHLPMPTFGPLAGVRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWEHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGMTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEICPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQINECFKDIGLAHILGTPEVPE
                     GTQLIHRVECPYGPLVEEKLDAWLAAHTIADVQARFAELNIACAKVLTIPELEGNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGKIWRGMPSHGMDTAAILKNIGYSEADI
                     KELVGKGLAKVED"
     gene            11317..12870
                     /gene="caiC"
                     /locus_tag="OPY25_000371"
     CDS             11317..12870
                     /gene="caiC"
                     /locus_tag="OPY25_000371"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HCS0926089.1"
                     /translation="MDIVGGQNLRQMWDDLAGMYGDKTALIFESCEGIVRQFSYASLN
                     EEINRTANLFYYLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESA
                     WILQNSQVSLLVTSAQFYPMYREIRQDNSTPLNHICLIGEQLPADDGVSHFSQLQARQ
                     SATLCYTPALSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYM
                     TVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWDQVRKYQATVTECIPMMIRTL
                     MVQPATPTDRQHHLREVMFYLNLSAQEKDAFTERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAR
                     ALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIV
                     VVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCS
                     GKIIKKNLK"
     gene            12924..13709
                     /gene="caiD"
                     /locus_tag="OPY25_000372"
     CDS             12924..13709
                     /gene="caiD"
                     /locus_tag="OPY25_000372"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HCS0926090.1"
                     /translation="MSESLHLTRNGPILEITLDRPKANAIDAKTSFAMGEAFLNFRDD
                     PELRVAIITGGGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVIAAVN
                     GYAFGGGFELALAADFIVCAENASFALPEAKLGIVPDSGGVLRLPKLLPPAIVNEMVM
                     TGRRMSAEEALRWGIVNRVVSQSELMESARELAQQLVNSAPLAIAALKEIYRATSEMP
                     VEEGYRYIRSGVLKHYPSVLHSEDALEGPQAFAEKRAPVWKGR"
     gene            13821..14417
                     /gene="caiE"
                     /locus_tag="OPY25_000373"
     CDS             13821..14417
                     /gene="caiE"
                     /locus_tag="OPY25_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HCS0926091.1"
                     /translation="MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLILEAGSNLQDGCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFQGEARQLLVGSPARVLRQVTDQELHWKRLNTKEYQ
                     DLAIRCRTGLSETKPLTQVEENRPRLKGTTDVKPKSAQ"
     gene            complement(14495..14890)
                     /gene="caiF"
                     /locus_tag="OPY25_000374"
     CDS             complement(14495..14890)
                     /gene="caiF"
                     /locus_tag="OPY25_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HCS0926092.1"
                     /translation="MCEKYVERPLYLLIADWMMAENRWITAREISRQFDIEHCKAINT
                     LSYILSEVGEIVCEVKMIPNQIAGRGCQCQRLVKVVSIDSQLYRRLNHNLQERKVSVA
                     KAPRLSAVPPTELNREQKWQMMLSKSMRR"
     gene            complement(15164..18391)
                     /gene="carB"
                     /locus_tag="OPY25_000375"
     CDS             complement(15164..18391)
                     /gene="carB"
                     /locus_tag="OPY25_000375"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCS0926093.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDIAMKKIGLDTARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGTGGGIAYNREEFEEICERGLDLSPTNELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVTEVGITGLNADFLRQLKRKGFADARLAKLAGV
                     REGEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEDECEANPSVDRDKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     DRLKLKQPANATVTAIEQAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDRFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKDNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLTEQGVTQEIIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKQGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTAGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATTMALNADATEKVTSVQEMHAQIKKS"
     gene            complement(18407..19555)
                     /gene="carA"
                     /locus_tag="OPY25_000376"
     CDS             complement(18407..19555)
                     /gene="carA"
                     /locus_tag="OPY25_000376"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCS0926094.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNEADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDSPDAKLALEKAKAFPGLNGMDLAK
                     EVTTAETYRWTQGSWTLKDGLPEAKSEDDLPFHVVAYDFGAKRNILRMLVDRGCRLTV
                     VPAQTSAEEVLKMNPDGIFLSNGPGDPAPCDYAIEAIKKFLQTDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDMDRNVVMITAQNHGFAVDEDSLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIKHYRSSAK"
     gene            complement(20060..20261)
                     /locus_tag="OPY25_000377"
                     /pseudo
     CDS             complement(20060..20261)
                     /locus_tag="OPY25_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_446529.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20417..21238)
                     /gene="dapB"
                     /locus_tag="OPY25_000378"
     CDS             complement(20417..21238)
                     /gene="dapB"
                     /locus_tag="OPY25_000378"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCS0926095.1"
                     /translation="MHEAQIRVAIAGAGGRMGRQLIQAAMAMEGVQLGAALEREGSSL
                     LGSDAGELAGAGKSGVIVQSSLEAVKDDFDVFIDFTRPEGTLTHLAFCRQHGKGMVIG
                     TTGFDDAGKQAIREASQEIAIVFAANFSVGVNVMLKLLEKAAKVMGDYSDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAGALDKDLKDCAVYSREGYTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERVEITHKASSRMTFANGALRSALWLKTKKNGLFDMRDVLGLDVL"
     gene            complement(21418..22326)
                     /gene="citG"
                     /locus_tag="OPY25_000379"
     CDS             complement(21418..22326)
                     /gene="citG"
                     /locus_tag="OPY25_000379"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HCS0926096.1"
                     /translation="MNVSVVTERRTPAYSSLAAGELNGLVARALLTEARLTPKPGLVD
                     IRNSGAHRDMDLAAFERSTTAIAPWMEKFFIMGNNTAALAAENVLVMLRPLGMACEND
                     MLQATNGVNTHRGAIFAFGLLSAAIGRLLARGEPLEQNRICDQVARLSRNIVAHELSA
                     RKAGKLTKSETHFQCYGLSGARGEAESGFRTVRTQALPVFNRVVQEHDDTHLALLQTL
                     LHLMAWNDDTNLVSRGGLEGLYYVQQQAQKLLWQGGVLVEGGIEAMQFLDDELILRNL
                     SPGGSADLLAVTWFLSHFPAGSLYPE"
     gene            complement(22304..22855)
                     /gene="citX"
                     /locus_tag="OPY25_000380"
     CDS             complement(22304..22855)
                     /gene="citX"
                     /locus_tag="OPY25_000380"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HCS0926097.1"
                     /translation="MKGTDLLYQGQAVTLEEMLQARDKRAARQRQALNCYRLPLISLT
                     LVAPGAVKNSAVWRRVADYAIAEILALCEQKEWVNVWEMQVNERSGPEWMAAVCAPAM
                     ALKQHMSTLEMSHPLGRLWDIDIIDSDGKSLSRRELGHPARPCLICQQDAHLCARGKH
                     HTLDLLLDEIARRIECYERERCD"
     gene            complement(22855..24375)
                     /gene="citF"
                     /locus_tag="OPY25_000381"
     CDS             complement(22855..24375)
                     /gene="citF"
                     /locus_tag="OPY25_000381"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HCS0926098.1"
                     /translation="MKETVTMLNQQYVVPEGLQPYQGVTVNSPWLASETEKRRRKICD
                     SLEEAIRRSGLKNGMTISFHHAFRGGDKVVNMVMAKLAEMGFRDLTLASSSLIDAHWP
                     LIEHIKNGVVRQIYTSGLRGKLGEEISAGLMENPVQIHSHGGRVKLIQSGELNIDVAF
                     LGVPCCDEFGNANGFSGKSRCGSLGYAQVDAQYAKCVVLLTEEWVEFPNYPASIAQDQ
                     VDLIVQVDEVGDPEKITAGAIRLSSNPRELLIARQAANVIEHSGYFCDGFSLQTGTGG
                     ASLAVTRFLEDKMRRHNITASFGLGGITGTMVDLHEKGLIKALLDTQSFDGDAARSLA
                     QNPHHIEISTNQYANPGSKGAACERLNVVMLSALEIDVNFNVNVMTGSNGVLCGASGG
                     HSDTAAGADLTIITAPLVRGRIPCVVEKVLTTVTLGASVDVLVTDHGIAVNPARQDLL
                     DNLRAAGVALMTIEQLQQRAEQLTGKPQPIEFTDRVVAVVRYRDGSVIDVIRQVKG"
     gene            complement(24386..25255)
                     /gene="citE"
                     /locus_tag="OPY25_000382"
     CDS             complement(24386..25255)
                     /gene="citE"
                     /locus_tag="OPY25_000382"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HCS0926099.1"
                     /translation="MRPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVALREKDT
                     ARLLVHHALQHPFYQDVEKVVRINPLNTPFGLADLEAVVRGGADIVRLPKTDSKNDVL
                     ELEAQVERIERECGREVGSTRLMAAIESAKGVVNAVDIATSSPRMVAIALAAFDYVMD
                     MGTSRGDGTELFYARCAVLHAARVAGIAAYDVVWSDINNEEGFLKEVQLAKGLGFNGK
                     SLVNPRQIELLHQAYSPTRKEVEHAHEVIAAAEEAESRGLGVVSLNGKMIDGPIIDHA
                     RKVVALSASGIRD"
     gene            complement(25252..25545)
                     /gene="citD"
                     /locus_tag="OPY25_000383"
     CDS             complement(25252..25545)
                     /gene="citD"
                     /locus_tag="OPY25_000383"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HCS0926100.1"
                     /translation="MKIIKDALAGTLESSDVMIRIGPSSEPGIRLELESLVKQQFGAA
                     IEQVVRETLAKLGVERALVSVDDKGALECILRARVQAAALRAAEQTEIQWSAL"
     gene            complement(25575..26618)
                     /gene="citC"
                     /locus_tag="OPY25_000384"
     CDS             complement(25575..26618)
                     /gene="citC"
                     /locus_tag="OPY25_000384"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HCS0926101.1"
                     /translation="MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVC
                     AYWQGEIVGCGSLAGNVLKCIAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKP
                     QNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
                     TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYM
                     ISRATFPGYFLKEKGVVDDCHCQIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQ
                     RMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERNWPAISALVPAGTLA
                     YLQRHAARHTETI"
     gene            26863..28203
                     /gene="citS"
                     /locus_tag="OPY25_000385"
     CDS             26863..28203
                     /gene="citS"
                     /locus_tag="OPY25_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/sodium symporter CitS"
                     /protein_id="HCS0926102.1"
                     /translation="MTNMTQASATEKKGASDLLRFKIFGMPLPLYAFALITLLLSHFY
                     NAIPTDLVGGFALMFVMGAIFGEIGKRLPIFNKYIGGAPVMIFLVAAYFVYAGIFTQK
                     EIDAISNVMDKSNFLNLFIAVLITGAILSVNRKLLLKSLLGYIPTILAGIVGASLFGI
                     VIGLCFGIPVDRIMMLYVLPIMGGGNGAGAVPLSEIYHSVTGRSREEYYSTAIAILTI
                     ANIFAIIFAALLDMIGKKYTWLSGEGELVRKASFKTEDDEKAGQITHRETAVGMVLST
                     TCFLLAYVVAKKILPSIGGVSIHYFAWMVLIVAALNASGLCSPEIKAGAKRLSDFFSK
                     QLLWVLMVGVGVCYTDLQEIIDALTFANVVIAAIIVVGAVVGAAIGGWLIGFYPIESS
                     ITAGLCMANRGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVIASIVFSMMV"
     gene            28362..28601
                     /locus_tag="OPY25_000386"
     CDS             28362..28601
                     /locus_tag="OPY25_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010836018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit gamma"
                     /protein_id="HCS0926103.1"
                     /translation="MNEAVLLGEGFTLMFLGMGFVLSFLFLLIFAIRGMSAVITRFFP
                     EPVAAPAPRAVPAVDDFTRLKPVIAAAIHHHRLNA"
     gene            28617..30392
                     /gene="oadA"
                     /locus_tag="OPY25_000387"
     CDS             28617..30392
                     /gene="oadA"
                     /locus_tag="OPY25_000387"
                     /EC_number="7.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-extruding oxaloacetate decarboxylase
                     subunit alpha"
                     /protein_id="HCS0926104.1"
                     /translation="MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAQLDDVGYGSLEC
                     WGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVE
                     RAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTE
                     QLLETGVDSIAIKDMSGILTPMAAFELVSEIKKRFEVRLHLHCHATTGMAEMALLKAI
                     EAGVDGVDTAISSMSATYGHPATEALVATLAGTEHDTGLDILKLENIAAYFREVRKKY
                     HAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADRLDQVLAEIPRVREDLGFIP
                     LVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGSA
                     PVTCRPADLLKPELAELEADVRRQAQEKGITLAGNAIDDVLTVALFPQIGLKFLENRH
                     NPAAFEPLPQAEAAQPVAKAEKPAASGIYTVEVEGKAFVVRVSDGGDISQLTTAVPAA
                     SSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQSVAEGDVLLILEAMKMETEIRAAQ
                     AGTVRGIAVKSGDAVSVGDTLMTLA"
     gene            30405..31706
                     /locus_tag="OPY25_000388"
     CDS             30405..31706
                     /locus_tag="OPY25_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalacetate decarboxylase subunit beta"
                     /protein_id="HCS0926105.1"
                     /translation="MESLNALLQGMGLMHLGAGQAIMLLVSLLLLWLAIAKKFEPLLL
                     LPIGFGGLLSNIPEAGMALTALESLLAHHDAGQLAVIAAKLNCAPDVHAIKEALALAL
                     PSVQNQMENLAVDMGYTPGVLALFYKVAIGSGVAPLVIFMGVGAMTDFGPLLANPRTL
                     LLGAAAQFGIFATVLGALTLNYFGLIAFTLPQAAAIGIIGGADGPTAIYLSGKLAPEL
                     LGAIAVAAYSYMALVPLIQPPIMRALTSEKERKIRMVQLRTVSKREKILFPVVLLLLV
                     ALLLPDAAPLLGMFCFGNLMRESGVVERLSDTVQNGLINIVTIFLGLSVGAKLVADKF
                     LQPQTLGILLLGVIAFGIGTAAGVLMAKLLNLCSKNKINPLIGSAGVSAVPMAARVSN
                     KVGLESNPQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVLAM"
     gene            31727..32458
                     /locus_tag="OPY25_000389"
     CDS             31727..32458
                     /locus_tag="OPY25_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase"
                     /protein_id="HCS0926106.1"
                     /translation="MIMLPQNEDTVMSEMVAFRQGTSMPSRETILRYVVETVNQITEL
                     EPALHLLPWSGVNSAIYEQRFAQCYDEGLCAAQTSAPNVPQGILPSTDWAQGIGLLCF
                     AAGYMSAGERPLTHNRLCDFVKQAAVGLSPIEGEAASGFSTVRSIALPVFRRLQRDGH
                     ASRVLLLQTLLHLVAWKSASQYARQQAQRLLWMGGILGEGSESGLLTLDKALREEAVG
                     EKSFPALLIFTSFLAHFPAGPVFID"
     gene            complement(32492..33562)
                     /gene="degS"
                     /locus_tag="OPY25_000390"
     CDS             complement(32492..33562)
                     /gene="degS"
                     /locus_tag="OPY25_000390"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HCS0926107.1"
                     /translation="MFVKLLRSVAIGLIVGAILLAVMPSLRKINPIAVPQFDSTDETP
                     ASYNFAVRRAAPAVVNVYNRSMNSTAHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINTKRTPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGLGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQQGSG
                     MDPIQGIVVNEVTPNGPAALAGIQVNDLIISVNNKPAVSALETMDQVAEIRPGSVIPV
                     VVMRDDKQLTFQVTVQEYPASN"
     gene            complement(33655..35022)
                     /gene="degQ"
                     /locus_tag="OPY25_000391"
     CDS             complement(33655..35022)
                     /gene="degQ"
                     /locus_tag="OPY25_000391"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HCS0926108.1"
                     /translation="MKKHTQLLSALALSVGLTLSAPFPALASIPGQVPGQATLPSLAP
                     MLEKVLPAVVSVKVEGTATQSQKVPEEFKKFFGEDLPDQPSQPFEGLGSGVIIDAAKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGGDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSIGIGFAIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEM
                     TADIAKAFKLNVQRGAFVSEVLPNSGSAKAGVKSGDVIISLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRDGKPLEVEVTLDSNTSSSASAEMIAPALQGATLSDGQLKDGTKGV
                     KVDSVEKSSPAAQAGLQKDDVIIGVNRDRISSIAEMRKVMAAKPSIIALQVVRGNENI
                     YLLLR"
     gene            complement(35179..35577)
                     /locus_tag="OPY25_000392"
     CDS             complement(35179..35577)
                     /locus_tag="OPY25_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HCS0926109.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LEEYREELVSHFARSAELLDTMAHDYRQLYQYMAKSSSSLLPEMSAESNPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRSGAKRD"
     gene            35770..36894
                     /locus_tag="OPY25_000393"
     CDS             35770..36894
                     /locus_tag="OPY25_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AFG1 family ATPase"
                     /protein_id="HCS0926110.1"
                     /translation="MQSLSPTSRYLQALNEGTHQPDDVQKEAVDRLETLYQALTAKKS
                     SATPPGGLIARLGKLLGKNEPDAQIPVRGLYMWGGVGRGKTWLMDLFYHSLPGERKLR
                     LHFHRFMLRVHEELTALQGQIDPLDIIADRFKTETDVLCFDEFFVTDITDAMLLGGLM
                     KALFARGITLVATSNIPPEELYRNGLQRARFLPAIDAIKQHCDIMNVDAGVDYRLRTL
                     TQAHLWLTPLNDETRRQMDKLWLALAGAAREHAPTLEINHRPLSTLGVENQTLAASFA
                     TLCVEARSQHDYIALSRLFHTVLLFDVPVMTPLMENEARRFIALVDEFYERHVKLVVS
                     AAAPLYEIYQGERLKFEFQRCLSRLQEMQSAEYLKREHMP"
     gene            37195..37623
                     /gene="rplM"
                     /locus_tag="OPY25_000394"
     CDS             37195..37623
                     /gene="rplM"
                     /locus_tag="OPY25_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCS0926111.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            37639..38031
                     /gene="rpsI"
                     /locus_tag="OPY25_000395"
     CDS             37639..38031
                     /gene="rpsI"
                     /locus_tag="OPY25_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCS0926112.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(38058..38231)
                     /locus_tag="OPY25_000396"
     CDS             complement(38058..38231)
                     /locus_tag="OPY25_000396"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926113.1"
                     /translation="MNIPRYLGRKLDDSLPDFVTFVVSRFWNWGKRDNNPHFIVTDKC
                     IAHKKTRQSGFFR"
     gene            38346..38984
                     /gene="sspA"
                     /locus_tag="OPY25_000397"
     CDS             38346..38984
                     /gene="sspA"
                     /locus_tag="OPY25_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HCS0926114.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNVIVNGSASEVDSARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGAGAKELKGYMTRVFERDSFLASLTEAEREMRLGRG"
     gene            38990..39490
                     /gene="sspB"
                     /locus_tag="OPY25_000398"
     CDS             38990..39490
                     /gene="sspB"
                     /locus_tag="OPY25_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HCS0926115.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVMLPGVHVPME
                     YARDGQIVLNIAPRAVGNLELSNDEVRFNARFGGVPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDVVSLNDDDNTAGAESETVMSVIDGDKPDHDDDSSPDDEPPPPRGGRP
                     ALRVVK"
     gene            39599..40390
                     /gene="nanR"
                     /locus_tag="OPY25_000399"
     CDS             39599..40390
                     /gene="nanR"
                     /locus_tag="OPY25_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HCS0926116.1"
                     /translation="MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMI
                     RRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQ
                     SLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVS
                     YQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQKMR"
     gene            40525..41418
                     /gene="nanA"
                     /locus_tag="OPY25_000400"
     CDS             40525..41418
                     /gene="nanA"
                     /locus_tag="OPY25_000400"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HCS0926117.1"
                     /translation="MAKALQGVMAALLTPFDHQQQLDSESLRRLVRFNIGQGIDGLYV
                     GGSTGEAFVQSLAEREQVLEIVAEEAKGKITLIAHVGTVSTAESQQLASAAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VNALKQTSGDLFQMEQIRRAHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVQALREGDVAKAQRLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFAP
                     VDEKYLPALKALAQQLMEEKA"
     gene            41534..43024
                     /gene="nanT"
                     /locus_tag="OPY25_000401"
     CDS             41534..43024
                     /gene="nanT"
                     /locus_tag="OPY25_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HCS0926118.1"
                     /translation="MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLAC
                     GFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILY
                     RGEHRIINILMTFAAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPT
                     GVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKS"
     gene            43071..43750
                     /locus_tag="OPY25_000402"
                     /pseudo
     CDS             43071..43750
                     /locus_tag="OPY25_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462247.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            43747..44622
                     /gene="nanK"
                     /locus_tag="OPY25_000403"
     CDS             43747..44622
                     /gene="nanK"
                     /locus_tag="OPY25_000403"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HCS0926119.1"
                     /translation="MTTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREA
                     LKALVEPLRAEARQVAIASTGIIQEGMLLALNPHNLGGLLHFPLVQTLETIAGLPTLA
                     VNDAQAAAWAEYHALPDDIRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLAD
                     PHGPVCGCGRVGCVEAIASGRGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSA
                     QVIARMIADVKAITDCQCVVIGGSVGLAEGYLEQVRAFLMQEPEPYHVALSAARYRHD
                     AGLLGAALLAQGDTL"
     gene            44619..45086
                     /locus_tag="OPY25_000404"
     CDS             44619..45086
                     /locus_tag="OPY25_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCS0926120.1"
                     /translation="MMMGEVQSLPSCGLHPRLLDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMQLTTQMPAGKKAELHEQYIDIQLLLTGVERIAFGMSGAARQCEEMHVEEDYQ
                     LCSQIADEQTITLQAGMFAVFMPGEPHKPGCAVGEPDDIKKVVVKVRASLLAA"
     gene            complement(45168..46448)
                     /locus_tag="OPY25_000405"
     CDS             complement(45168..46448)
                     /locus_tag="OPY25_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine deaminase"
                     /protein_id="HCS0926121.1"
                     /translation="MQNNNITIRQTRLQGHEGLWQITIENGRFSRIEPQEATSLPQGE
                     VLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGTLFEGIERWAERKAMLTHEDVKA
                     RAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGIL
                     SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEI
                     DDEQSRFVETVAALAHRDGMGARVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANP
                     LVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWYPLGTANMLQVLHMG
                     LHVCQLMGYGQINDGLNLITTHSAKTLHLQDYGLSVGNAANLVILPAENGFDAVRRQT
                     PARYSIRHRRVIAETVPSQTTLHLTQPEAVTFKR"
     gene            complement(46435..47688)
                     /gene="codB"
                     /locus_tag="OPY25_000406"
     CDS             complement(46435..47688)
                     /gene="codB"
                     /locus_tag="OPY25_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HCS0926122.1"
                     /translation="MSQDNNYSQGPVPQAARKGVIPLTFVMLGLTFFSASMWTGGTLG
                     TGLTYHDFFLAVFFGNLLLGIYTAFLGYIGAKTGLSTHLLARYSFGVKGSWLPSLLLG
                     STQVGWFGVGVAMFAIPVSKATGIDANILIAVSGLLMTLTIFFGISALTILSIVAVPA
                     IVILGSYSVWLAVSGVGGLEHLKTIVPQTPLDFSSALALVVGSFVSAGTLTADFVRFG
                     RHAKSAVLIAMVAFFLGNSLMFIFGAAGAAAVGQADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGLSSRTLSVVNGIIGTVCALWLYNNFVGWLTFLSSAIPP
                     IGGVIIADYLVNRRRYADFNTVRFIPVNWIAILSVALGIAAGHYVPGIVPVNAVLGGV
                     FSYILLNPLFNRSLAKSPEVSHAEQ"
     gene            complement(47805..48908)
                     /locus_tag="OPY25_000407"
     CDS             complement(47805..48908)
                     /locus_tag="OPY25_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HCS0926123.1"
                     /translation="MTNPTLAPQSDEYQQIHDGIIRLVDTARTETVRSINAIMTATYW
                     EIGRRIVEFEQGGEARAAYGTQLIERLSVDLSQRYKRGFSNRNLWQIRTFYLCFQHIE
                     IPQTLSAESSNLIPLAKTFPLPWSAYVRLLSVKDNDARTFYEKETLRNGWSVRQLDRQ
                     IATQFYERTLLSHDKSAMLQQPAPAEPNVLPEQAIRDPFILEFLNLKDEYSESDLEDA
                     LLSHLMDFMLELGDDFAFVGRQRRLRIDNSWFRVDLLFFHRRLRCLLLVDLKVGKFGY
                     ADAGQMNMYLNYAKEHWTMPGENPPVGLVLCAGKGAGEAHYALTGLPNTIMASEYKVQ
                     LPDEKLLTDELIRSQTMLETQLTRGGSLTTEKN"
     gene            complement(49116..50534)
                     /gene="gltD"
                     /locus_tag="OPY25_000408"
     CDS             complement(49116..50534)
                     /gene="gltD"
                     /locus_tag="OPY25_000408"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HCS0926124.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKLRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLHDEFGAVTIGNIERYINDKAFEMGWRPDMTGVRQTDKRVAIIGAGPAGLA
                     CADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLEDLLKDYDAVFLGVGTYQSMRGGLENEDADGVFDALPFLIANTKQIMGFGE
                     TSDEPYVSMEGKRVVVLGGGDTAMDCVRTSIRQGATHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFQFNVQPLGIEVNANGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHVVPA
                     DAVVMAFGFRPHSMEWLAKHSVELDSQGRIIAPERSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNYLEV"
     gene            complement(50544..55004)
                     /gene="gltB"
                     /locus_tag="OPY25_000409"
     CDS             complement(50544..55004)
                     /gene="gltB"
                     /locus_tag="OPY25_000409"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HCS0926125.1"
                     /translation="MLYDKSLEKDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAEERGWRLAKNYAVGMIFLNKDPELAAASRHIV
                     EEELQQETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLQDDKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLQSAAPFVNET
                     GSDSSSLDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDQDLRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRGGRILHSAETDDDLKSRHPYKAWMEKNVRRLVPFEELPDEEVGSRELD
                     DDLLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMSEHHYRADWLDITFDVTETTLDATVKALCDKAEQMVRNGTVLLVLSDRNIGKNRLP
                     VPAPMAVGAVQTRLVDQSLRCDANIIVETGSARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLIDTQAIAKNYRTVMQNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VNLCFQGVVSRIGGASFDDFQQDLLNLSKRAWLARKPISPGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPAATLRDLLAIHPDGEAVTIDEVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSLGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDEKLRKNHYHGLPFKVTNYFEFIARE
                     VRELMASLGVTRLVDLIGRTDLLKELEGFTAKQQKLALSRLLETAEPHPGKALYCTEN
                     NPPFDNGVLNAQLLQQAKPFVDARQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     SDPIKAHFSGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFLSH
                     KASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCVL
                     GKTGVNFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVDSLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILSRWSSFSTQFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            55676..56605
                     /locus_tag="OPY25_000410"
     CDS             55676..56605
                     /locus_tag="OPY25_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462239.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCS0926126.1"
                     /translation="MQLQKLVNMFGGDLLRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHHSIAEQLAHQAHLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQASIVGLCVGTRPDCVPQAVVDLLCEYKDQGYEVWLELGLQTAHDKTLRRINRG
                     HDFACYQRTTRIARERGLKVCAHLIVGLPGEGQAECLQTMERVVETGVDGIKLHPLHI
                     VKGSTMAKAWEAGRLNGIELDDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDKYLNEHGVQGSALARPWIPPVA"
     gene            56698..59034
                     /gene="arcB"
                     /locus_tag="OPY25_000411"
     CDS             56698..59034
                     /gene="arcB"
                     /locus_tag="OPY25_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HCS0926127.1"
                     /translation="MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     KLNVQLKDNIAQLNQEIADREKAEAELQETFEQLKVEIKEREEAQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVSSLPGKGSTFTLTVHAPAV
                     AEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFA
                     PGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDD
                     VLSKPLSVPALTAMIKKFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLI
                     TDGLAVFEKMMLGYLSVLESNLTARDKKGVVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVVEWIEEMKQEWQHDVAVLKAWVANAEKK"
     gene            59261..59914
                     /gene="elbB"
                     /locus_tag="OPY25_000412"
     CDS             59261..59914
                     /gene="elbB"
                     /locus_tag="OPY25_000412"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HCS0926128.1"
                     /translation="MKKIGVVLSGCGVYDGTEIHEAVLTLLAIARSGAQAICFAPDKP
                     QADVINHLTGEAMAETRNVLIEAARITRGDIRPLSQAQPEELDALIVPGGFGAAKNLS
                     NFASKGSECRVDSDVVALAKAMHQSGKPLGFICIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKVVTTPAYMLAQDIAQAASGIDKLVSRVLVLAE"
     gene            59911..60639
                     /gene="mtgA"
                     /locus_tag="OPY25_000413"
     CDS             59911..60639
                     /gene="mtgA"
                     /locus_tag="OPY25_000413"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HCS0926129.1"
                     /translation="MSKRRIAPLTFLRRLLLRILAALAVFWGGGIALFSVVPVPFSAV
                     MAERQISAWLGGEFGYVAHSDWVSMADISPWMGLAVIAAEDQKFPEHWGFDVPAIEKA
                     LAHNERNESRIRGASTLSQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGIFGVEAAAQRYFHKPASRLSVSEAALLAAVLPNPLRYKANAPSGYVRS
                     RQAWIMRQMRQLGGESFMTRNQLN"
     gene            complement(60714..61346)
                     /gene="yrbL"
                     /locus_tag="OPY25_000414"
     CDS             complement(60714..61346)
                     /gene="yrbL"
                     /locus_tag="OPY25_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HCS0926130.1"
                     /translation="MILLSKQTPLGAGRHRKCYTHPDNARRCIKVIYNRDHGGDKEIR
                     RELSYYAHLSRYLTDWSAIPRYYGTVETDCGTGYVYDMITDFNGAPSITLTEFAAQCR
                     YEEDVAVLRRLLKKLKRYLLDNHIVTMSLKPQNILCQRISESEVVPVVCDNLGESTFI
                     PLATWSTWCCERKLERVWQRFIAQPALAVALERDAQPKDKKRLALTSHEA"
BASE COUNT        14016 a        16539 c        16675 g        14236 t
ORIGIN      
        1 ctggcagcgc attattttac attgacaaca acataaagag gtgactataa caagatataa
       61 gacggtcaca ccaaataagg ctattttcag ataatcaacc gaggttatta cccaaaataa
      121 ttcgagttgc ttaaaggcgg caagggagtg agtcaccagg agcatagata attatgtgac
      181 tgaggtgagc gacaaatctg ccgggagcag atttgaacgt cgcgtgcgac ggcccgtcag
      241 ggcgaggccc atgggtgggc cgagtaatcc gtagccaaca cataagcaac ctgaagtatg
      301 aagggtataa ataatttcgt tacggattac tgatattgcg caaaccttat catcaatgca
      361 acaggaacag aactatgaaa aaacgcatca ttgccgccgc attactggca acggttgctt
      421 cattcagcac acttgcggca gagcaggtct ctaagcaaga aatcagccac ttcaaactgg
      481 ttaaggtcgg caccataaat gtgtcccaga gtggcgggca gatttcctca ccctctgatc
      541 tacgcgaaaa actgtcagaa ttagccgatg cgaaaggcgg aaaatattac catattatcg
      601 ctgcacgtga gcatggtccg aattttgaag ccgttgccga agtttataac gatgcgacga
      661 aataaagctc tgattgcgcc ataacgatgg cactggcatg aaataataag agagcgccag
      721 caaggtgcca tgttacgtca caatccactc agggccgtct ggaaacagat gctggccctc
      781 ttttttatca acagttcatc cggggcaggc aagccgttgg aatgtgcgcg cgcaggcagt
      841 aagcccttcg tgaataagac ggttttgcgg gctgttttaa ggtaatattt agtgcgcttt
      901 tacctgcctg aaccagtaat tttccatttt cgttatccat ttcccctttt tatttttcgg
      961 tattacgcca gcccaaagta attgcagctg tcggttatag gttccaatag cgtgtccacc
     1021 atacgcccct tcaaatgcta tcaccatggg tccctgccct tttaccccct cttgtccttc
     1081 atggcaataa agcgcgttgc ggtgagtcac gtcaagttca tactgtacgt tcagtttcac
     1141 acatttttcc ccgcagcctt ctactggcgg caatattgtc atggtataag gcgggttatc
     1201 tgcagtggtt ttccatgttc cgatcaggtc tttgcaggcg tttatctccg tagccccgga
     1261 ggcggcagaa aatagcgcga gcaaataaaa aggtattagt ttcagtttca ttacagactc
     1321 cgtttcctta tacctaatca tttataccta atcataagga taaatgcctt gcgatatgtt
     1381 ttttccggga aatgttgagc cgctgttcag agaaatgtcg atgagtgtaa cctcatgtaa
     1441 gcggacagcg cggtggggaa agcgggaaca cgggcgaacg tatttcgacg ttttccggcg
     1501 tccctgccag ttcaggcatc cgtttattcg catgggaata aatggatgcg cataaagaga
     1561 gaatattatt gcgcggctaa ccagaaaaaa ttgaattaat tatccagctc gctcatattt
     1621 ttcagctgat cgcggttaat ctgttcggtt ttcccggtgg cggcgttttt gtaagacacc
     1681 ataccggtat cgttatcgac ctcgggtttc ccgtcggtga caatagtttt gccatccgtg
     1741 gtttcaaccg cctggttaga agagcatcct gcgacggtga atagtgttgc tgcggtaaac
     1801 agtgcggtca taagacgttt ttgcatggtg ttctccctgc ttttcagttg ttttagcatg
     1861 tgactgttaa ctgtagcgtt attggcgaaa agcagggaga aatgcagaac actcttaacg
     1921 agggttatcc gatggcgttc cgcgcaaagt catgtttccg gtctgtgtta gcgtcaagcc
     1981 gcgagtttcc ggggcaaaca tcaccgatac gccaagcccg actaacgaaa tcaacgcgcc
     2041 aatcagcatg acgttattaa taccgtaacg agtaataaaa atcggtaatg cccaggtgga
     2101 gacaatggtt ccgatacggc ttaatgacat gatgaccccc acggccgaag cgcgaatatc
     2161 cgtagggaag agttcattag gataaagcca ttgcagtatg cccggtccgc cggaaaagaa
     2221 ggcgtatacc gcaaacgcca ccacgaccag tatgataccc agatttgaca ccagccccag
     2281 cagcgccagc gcgatagtca tcatggcgaa gctgccaata agcagagggc gacggccaat
     2341 actgtttagc cagaacatcg ccggtataca gcccagcata aaaaagaggc taatcaccac
     2401 attgccgagc gccgcgttgc gcccctgttc ccagccgagt aacccgacga tctgcggccc
     2461 aaaggtatag atagcgaaca tcgggatcac ctgacagctc cagatagccg caacgaacag
     2521 tacaaacggg aaatgacggc ggttaaacag ctgcaggaag cgggtctcct gcggcggctc
     2581 atcgtcaaag cagaccggtt cgccgaacag tttgatcatc atttgttcgc actcttttac
     2641 ccgtcctttt cgcaatagcc agcgtggcga ttccggcagg tcaaagcggc caatcaaaat
     2701 gattaagcac gggataaagg cgctgccaag catccagcgc cagcctcctt ccatgtcata
     2761 cagccagtaa cccaccaggt tggcgcaggt cgcgccgacg taccacatcg cggcgataaa
     2821 accgatggag aacgcacgct ggcgggtgtt ggaaaactcc gtaatcatgg aagtggcgat
     2881 agggtaatcc gcgccgataa caatgccaat taaaacgcgc atcaccagca attcaagcgg
     2941 cgtggaaaca aacatggtcg ccacggagat aacgccgata gcgataatat caagcaggaa
     3001 cattttacgc cgcccgactt tatcgcaaat atagccaaac aacgaggtgc cgataaacag
     3061 tccggcaagc gtagccgcgc cgagcgcgcc aatccattca gcatcaaggt gcaatagcgg
     3121 cgtcagttgt tccagcgcca cgccaatgat caccagcacg tagccatcaa ggaacgggcc
     3181 gccgcttccc cacagcataa ttctgcgatg gatggaggag aatttaaggt cgtcaaagtt
     3241 cctgggctgc ggcatggtga tgtcctgttt caacacgggc aaagcgtcat ctgtaggccg
     3301 gataaggcgt ttacgccgcc atccggcatt ggcgccacat gattgccgga tggcgacgct
     3361 accgcatcta atccggccta cgggggcaca aactcgtact tattagccgt agcggaactc
     3421 cacgccaaac gtcccgcgtg ggtattccca tttttccagc gccgtatcaa ggccgaggat
     3481 ccggcatgtt ccgcactcca ggcacccggc gtaatcaaaa cgaacgctac cgtcgtcctg
     3541 ctttttatac agtcccgccg gacaggcctt aaccagcacc tccagcgcct gtttatcagg
     3601 atcggttttg agaatgatgt gcgggctatc ttcatccaca ttgaacttat tgacgcccaa
     3661 tttgacgtcc acattgacgg gagatgtcat aatacggtca ctcctttcag gccatctttc
     3721 atcaggttga tgaagcccac tttcttcgca tggcgcagga tttttttacg catgggcacc
     3781 ggcgcggagc catccacggt gaacaggtcg cgcgcgatac tgaccgccat ttcgggatag
     3841 gcggtaaaca tgcggggatt atcaagaaaa gctggcagtt tctgatacat gcgcatatcg
     3901 cgcatcggac cttcgtccag atgctgacgg tattcaccca acgactgctt gctaaaatcg
     3961 tcgcgcttca tcgccgaaag caccgtcttc gccgccgctt cgcctgcgga tatggcgaga
     4021 tccatacccc ggatggtaaa gccgaggttc atacacatgc cggcagcgtc tccggcaatc
     4081 agtacaccat cgcccaccag ttcaggctgc atattcattc ccgcctcggg tacaacgtgt
     4141 gcggcatatt ccaccagctt gccaccggcg atcagcggcg caacggccgg atgctgtttg
     4201 aaatcttcca gcatttgcgg gaccgatttt ttcgcgtctt tcagatgatg aagaccgcag
     4261 accagcccta gggaaagggt tgtttcattc gtatacagga agccaccgcc catcagacca
     4321 tcggttggcg ccccggcaaa cagacaggcg gcaccttcgt tgccctgtag ctggaaacga
     4381 tcttcaatga ccgacttcgg caattcgatc agttccttca caccgacggc aacatgcgat
     4441 gcctcaacac gcttggccat gcccagcttt tcagccagca gagaattcac cccgtcagcg
     4501 aggattacga ctttggcttc cagaatatcg ccatcggctt ccacgcccac gactttgcca
     4561 tcacgctgaa caacgttatc cacgcgaata ccggtgatca gttgcgcccc cgcctcttcg
     4621 gcctgctcca tcagccaggc gtcaaattta ctacgcaaaa cggaataaga aacctgcgac
     4681 gctgaagcat cttcaccatt gcagtagtcg atagtcatcg ccccgttgtc ggtcataaag
     4741 gcgagttttt cgtgggtgat catgcgttca atgggggcct gatccgcaaa gccgggaatg
     4801 atgcgttcca ggctatgtgc atacaaacgc ccaccggtga cattcttcgc gccagcagaa
     4861 ttgccgcgct cgataaccag cacctgtgca ccttcgcgag caagcaccag cgccgcaacc
     4921 gaaccggcca gacctgcacc cacgatgatg gcatcaaaga tatcttcgga catacgtact
     4981 cctgtcagcg gcaggatacc ttcgtatcct gcccgaaatg gtttatcgcg ctaaggcagc
     5041 cgtcagcgca ggcaggatct tcagcgcatc gccaacgatg ccaaaatccg catactggaa
     5101 gattggcgcg tttttatctt tgttgatggc gaaaatcgtc tgcgcgccgt tggcgccgac
     5161 catgtgttgg atctgcccgg agatccccac cgccagatac agttcaggtt tgagcatcag
     5221 gttggagata ccgacgtagc gctcgtgctc catccacttc tcgttttccg ccaccgggcg
     5281 ggaacaggcc agctcggcgc cgatggtctg gcacagcgct tcggccagcg agatattctc
     5341 tttgctgccg atgccgcgtc ccacgctgac caccagacgc gctttgtcga ggtcaacgct
     5401 gttgctctga cgcgcctggg ttgcggtgcg ggtcacggca gtggccggag cctgccactg
     5461 cacggtgtgc atctcgccgc tgcgagaagc atccggctgt tgtgcgtcaa acgttccgct
     5521 gctgagtgtg atcacggcaa acggcgaagc gatggtctct gcccctatcg ccagaccgcc
     5581 gtagaccata tgtttgaccg ccgcttttcc atcctgcagg gagacgtcgc tggcgtcgtt
     5641 ggaaaccgca gccgacaagc gatagcccag ttttgccgcc aacagcttgc cccgacgcgt
     5701 attcggcagc agcaccgcgc cgccctcgct atgctgacga atagtctcag ccatcgcagc
     5761 agcgtagtct tcgatcatgc gatcttctgg tttgccgctg agcagccaga catgatccgc
     5821 gcccaaatga catgctgtcg cgctgtccgc ttcgttcagt acgaacgcgt taactttttc
     5881 acctacagcc tgcgcaccac tcatcagttc gggcagacga gaaggggtat cgctgaatac
     5941 ccagacactg gaaaatttgt tcataacatc ccctgataat taaatgattt tgcgcagatt
     6001 ctcgacaaac gcggcgattt gttcttcacc gtcaccttca atcaccacac gctgacgctc
     6061 gcgctgcttc ggtgcggcaa cctgttgtgt ggaatacgcg ggtacgctgt tcagcccgat
     6121 atccgcaggc gaccagacct gaaccggttt tttcgccgcg ccaagaatgg ctttcatcga
     6181 agggatttgt ggggtgttaa tgtcggtgga aaccgcgatc accgccggga gcgggatgct
     6241 cagcgtttca acttcatctt ccagttcgcg ttctaccgtc aatgtgctgt cggtaagaga
     6301 gaggatttta ctcacgccgt taatcgccgg aatgttcagc gcttcgccca ccagcaaacc
     6361 aacctgctga gcataaagat cggaagaacc gtcgccgcag ataagtagat cgaaacctga
     6421 tttttgcgcc gcggcggcca gcgcggtagc ggtgtgttgc ggcagcgcct gctcaaattg
     6481 atcgtcaatg accacaatca gttcatcagg gccacgagag aggacatctt tgcgcccttt
     6541 tgcattagtc agcgctttgc cgccaacgct catggcgaca acctgagcgt ctcccaactg
     6601 ctgttttaac tggcaagcag cttcaattgc attcagatca tattggctga ttttgctatc
     6661 cgctttgctg aaatcgagtg ttccgtcagc attattaatc gcaatatcct gctcatcagg
     6721 tacgcatttg tagcaagtaa ttatcttcat tgcatctcca gaaatcatga aggaaacgta
     6781 tttatatcgg cggtgttaaa tacagatatc acgctcttta attcggaaat aaaaccttaa
     6841 tcaccaatat tgaaaatgtc acacattgat attcgtaact ttcaatagtg ttacgcacct
     6901 caccaatatt gaaagaaata tgccaaatat gaaaattttc aatattgttt gctggctcaa
     6961 caatattgaa cgccagatac ttaaaaaagt taaaaaacca caaccaacag attgataaat
     7021 aaagaaaaaa tcaaaattta aacacaaaat aatcaacgca aaaaagtgtg acacagataa
     7081 cagaatcacc cgaaatgaat acccattatg agttactcat tgaggcgtcc cagaggttaa
     7141 aaacttatca acaaatcatt aataataaat aaacaaacgt tcatgaactg gcacgctaaa
     7201 taaatttcgt tttcacactg gaattcactt atgaaaaatg aaaagagaaa atcgggaatt
     7261 gaaccgaagg ttttttttcc gctattaata attgtcggga tactttgctg gctaacagtc
     7321 agagatcttg atgccgctaa cgtcgttatt aatgcggtat tcagttatgt caccaacgtc
     7381 tggggttggg catttgaatg gtatatggtc gtcatgctct tcggctggtt ctggctggtt
     7441 tttggcccct atgccaaaaa gagattaggt gacgaaaaac cggagtttag caccgccagc
     7501 tggattttca tgatgttcgc ctcctgtaca tccgctgcgg ttctgttctg gggctctatt
     7561 gagatctact actatatctc caccccgccg ttcggcctgg aacccaattc cacgggcgcg
     7621 aaagagatag gcctggcgta cagcctgttc cactgggggc cgctaccgtg ggcaacctat
     7681 agcttccttt ccgtggcctt cgcctacttc ttctttgtac gcaagatgga tgtcatccgc
     7741 cccagctcca cgctggtacc gctcgtcggt gaaaagcatg cgaaagggtt gttcagtacc
     7801 atcgtcgata acttctacct ggtggcgctg atcttcgcga tgggcaccag cctcggtctg
     7861 gctaccccgc tggtcaccga gtgtatgcaa tggctgttcg gtattccgca tacgctgcaa
     7921 ttggatgcca tcatcattac ctgctggatc attctgaacg cgatttgcgt ggcctgcggc
     7981 ctgcaaaaag gggtcagaat cgccagcgat gtgcgtagct acctgagctt cctgatgctc
     8041 ggctgggtgt ttatcgtcag cggcgccagc ttcatcatga actacttcac cgactccgtc
     8101 gggatgctgt taatgcacct gccacggatg ctgttctata ccgacgccat cggtaaaggc
     8161 ggcttcccac agggctggac cgttttctac tgggcgtggt gggttattta cgccatccag
     8221 atgagtatct tcctggcccg tatttcccgt ggtcgtaccg tacgtgaact gtgcttcggg
     8281 atggtgatgg gtctgaccgc gtctacctgg atcctgtgga cagtccttgg cagtaacacg
     8341 ctgctgctga tggataaaaa catcctcaac atcccgcaac tgattgagca acacggcgtg
     8401 gcgcgcgcca ttatcgaaac ctgggcagcc ttgccgctca gcaccgccac catgtggggc
     8461 ttcttcatcc tctgctttat tgccaccgtc acgctgatta acgcctgctc ttacaccctg
     8521 gcgatgtcga cctgtcgcga agttcgcgat ggtgaagagc cgcctctgtt agtacgcatc
     8581 ggctggtcgg tgctggtcgg catcatcggt atcgttctgc tggcgctggg tgggttgaag
     8641 ccgattcaga ccgcgattat cgccggagga tgcccgctgt tcttcgtcaa cattatggtg
     8701 acgctgtcct ttattaaaga cgccaaagtg cactggaaag acaagtaatt cttattaacc
     8761 caattgatca agaggctgaa agatggattt caacttaaat gacgaacagg agctgtttgt
     8821 cgccggtatt cgcgaactga tggccagtga gaactgggaa gcttattttg ccgagtgcga
     8881 tcgtgacagc gtctaccctg agcgttttgt aaaagcgctg gcggatatgg gtattgatag
     8941 cctgctgatc ccggaagaac acggcggtct ggaagcgggt tttgttaccg tcgccgccgt
     9001 ctggatggaa ctgggacgtc ttggcgcgcc aacttacgtg ttgtaccaat tgccgggagg
     9061 ttttaacact ttcctgcgtg aagggactca ggagcaaatt gataaaatca tggcgttccg
     9121 gggcaccggt aagcagatgt ggaactctgc tatcaccgaa ccgggagcgg gatcggatgt
     9181 tggtagtctg aaaaccactt atacacgcaa aaatggtaag gtttatctca atggcagtaa
     9241 gtgctttatc accagtagcg cctatacccc gtacatcgtg gtcatggcga gagacggtgc
     9301 atcgccggat aaaccggttt acaccgagtg gtttgtggac atgagcaaag cgggtatcaa
     9361 ggtcaacaaa ctggagaaac tcggtctgcg catggatagc tgctgtgaaa tcacctttga
     9421 cgacgttgaa ctggacgaga aagacatgtt cggtcgggaa ggtaacggct tcaaccgcgt
     9481 gaaagaagag tttgaccatg aacgcttcct cgtcgcgctg accaactacg gtaccgcaat
     9541 gtgcactttt gaagacgctg cgcgttacgc taatcagcgc gtgcagtttg gtgaagctat
     9601 tggccgtttc cagctgattc aggagaagtt tgcgcatatg gcgatcaaac tgaactccat
     9661 gaaaaatatg ctgctggaag ccgcgtggaa agcagataac ggcactatta cctccggcga
     9721 cgcggccatg tgcaaatact tctgcgccaa cgccgcgttt gaagtggtag acaccgccat
     9781 gcaggtactg ggaggtgttg gtatcgcggg caaccaccgc atcacgcgtt tctggcgtga
     9841 cctgcgcgtt gaccgtgttt ctggtggttc tgacgaaatg cagatcctga cgttgggtcg
     9901 tgcggtactc aagcaatacc gctaatcgat cccttgtagg cctgataaga cgcggggcgt
     9961 cgccatcagg caatcatgcc ggatggcgct gtgcttatcc ggcctacata ccgcaaaaaa
    10021 tgccaggaga aaaacgatga atcatttacc aatgccaacc tttggtcctc ttgctggggt
    10081 acgcgttgtt ttttcaggga tcgaaatcgc cggtccgttc gccggacaga tgttcgccga
    10141 atggggcgcc gaggttatct ggattgaaaa cgtcgcatgg gccgatacca tccgcgtaca
    10201 gcctaactac ccgcagctct cacgccgcaa cctgcacgcc ctgtcgctga atattttcaa
    10261 agatgaaggt cgggaagcgt ttctgaaact gatggaaacc accgatattt tcattgaagc
    10321 cagtaaaggc ccggcctttg cccgccgtgg tattactgat gaagtgctgt gggaacataa
    10381 cccgaaactg gtcattgccc acctttccgg cttcggccag tatggtaccg aggagtacac
    10441 caatcttccg gcgtataaca ccatcgcgca ggcattcagt ggttatctga tccaaaacgg
    10501 cgacgttgac caaccgatgc cagccttccc gtataccgcc gattacttct ccgggatgac
    10561 cgcgacgaca gccgcgctgg cagccctgca caaagtacgc gaaacgggta aaggtgaaag
    10621 catcgatatc gccatgtacg aagtgatgct gcgcatgggt cagtatttca tgatggacta
    10681 cttcaacggc ggcgaaatct gtccacgtat gacgaaaggg aaagacccct actacgccgg
    10741 ttgcggcctg tataaatgcg ccgatggtta catcgtcatg gagttggtcg gcatcacgca
    10801 aatcaacgag tgttttaaag atattggcct ggcgcacatt ctcggtacgc cggaagttcc
    10861 ggaaggcacg cagctcatcc atcgcgtgga atgcccttac ggcccgctcg tcgaagagaa
    10921 actggacgcc tggctggcag cacataccat cgccgacgtt caggcgcgtt ttgctgagct
    10981 gaatatcgcc tgtgcgaagg tgctcaccat tccggaactg gaaggtaacc cgcagtacgt
    11041 tgcccgcgaa tcgattactc agtggcaaac aatggacggt cgcacctgta aagggccgaa
    11101 catcatgccg aaatttaaaa acaacccggg gaaaatctgg cgtggcatgc catcacacgg
    11161 catggatacc gccgccattc tgaaaaacat tggttatagc gaagcagata ttaaggaact
    11221 ggtcggcaaa ggcctggcca aagttgagga ttaaacgcga tgcgctactc ggttttccgg
    11281 ttagcgctca cgcctgattt cagtggataa agcaatatgg atatcgttgg cggacaaaac
    11341 ttacgtcaga tgtgggacga cctggccggg atgtacggag ataaaacggc gttaattttc
    11401 gaatcctgtg agggaatcgt tcggcagttt agctatgctt cgctcaatga agagattaac
    11461 cgcacggcga acctttttta ttacttaggg atccgcaagg gtgatagggt cgcgctgcat
    11521 ctggataact gtccggaatt catcttttgc tggtttggac tggcaaaaat cggcgccatt
    11581 atggtgccga ttaatgcccg cttactgggc gaagaaagcg cctggatcct gcaaaacagc
    11641 caggtgagtc tgctggttac cagcgcccag ttttatccta tgtaccgtga aatacgccag
    11701 gacaatagca ctccgcttaa tcatatctgt ctgattggcg agcagcttcc ggctgacgac
    11761 ggcgtgagcc acttttccca actacaagca cgccagtcgg ccacgctgtg ctatacgccc
    11821 gcgttatcca ctgacgatac ggcggaaatt ctgtttacct ccggtaccac ctcgcgtcca
    11881 aaaggggtgg tgattaccca ctataacctg cgctttgcag gctattactc tgcctggcaa
    11941 atcgccctgc gcgatgatga cgtgtacatg acggtgatgc ccgcttttca tatcgactgc
    12001 cagtgtaccg ccgcaatgcc agccttttcc gccggcagca cctttgtgct cctggagaag
    12061 tacagcgcca gggccttctg ggatcaggta cgtaaatatc aggcgacggt gaccgagtgc
    12121 atcccgatga tgatccgcac gctgatggtc cagcccgcca cgccaacgga caggcagcat
    12181 catctgcgcg aagtgatgtt ctatctcaat ttatccgcgc aggaaaaaga cgcctttacc
    12241 gaacgctttg gcgtcaggct gctgacctct tatggtatga ctgaaaccat tgtcggaatt
    12301 attggcgacc gtcccggaga caaacgacgc tggccttcca ttggtcgcgt gggctttagc
    12361 tatgaagctg aaattcgcga cgatcaaaat cgcccgctgc ccgccggaga aattggcgaa
    12421 atctgtatta aaggcatccc cggcaagact atcttcaaag agtattacat gcagccggag
    12481 gcaaccgcca gggcgctgga accagagggc tggttacata ccggtgattc gggttaccag
    12541 gatgaggatg gctatttcta ttttgtcgac agacgctgca acatgattaa acgcggcggg
    12601 gaaaatgtct cctgcgtcga gctggaaaat attatttctg cgcatccgaa aattcaggac
    12661 attgtggtgg tcggtattaa agacgcgatc cgtgatgaag ccattaaagc gtttatcgtc
    12721 cttaatgaag gtgaaacatt aagcgaggcc gagtttttca gcttctgcga aaacaatatg
    12781 gcgaaattca aagttccctc ttttatggag atcagaactg acctgccacg caactgttca
    12841 ggaaaaataa tcaaaaaaaa tctgaaataa accttccggc aggaatccct cccgccggga
    12901 aactatttat ctggagatga actatgagtg agtcattaca tctgacccgt aacggcccga
    12961 tcctggaaat taccctcgac cgacctaaag cgaatgccat tgatgcgaaa accagttttg
    13021 cgatgggtga agcttttctt aatttccgtg acgacccgga attacgcgta gcaatcatta
    13081 ccggcggcgg ggagaaattc ttttctgcgg gctgggactt aaaagcggca gcggaaggtg
    13141 aagcgccgga tgccgatttt ggtcccggcg gctttgccgg tttaaccgaa atatttgacc
    13201 tcgataagcc ggttatcgcc gcggtgaacg gctacgcatt tggtggcggt tttgagctgg
    13261 cgctggcggc agactttatt gtctgcgccg aaaacgccag cttcgcgctg ccggaagcca
    13321 agctcggcat cgtgcctgac agcggcggcg tattgcgtct gcctaagctg ctgccaccgg
    13381 ctatcgtcaa cgaaatggta atgaccggca gacgaatgag cgccgaagaa gcgctgcgtt
    13441 gggggatcgt gaaccgcgtt gtcagccaga gcgaactgat ggagagcgcg cgcgaactgg
    13501 cgcaacaact ggtcaatagc gctccgctgg ctatcgcggc gctgaaagag atttatcgcg
    13561 cgaccagtga aatgccggtt gaagaaggct accgctacat ccgcagcggc gtgctgaaac
    13621 attatccgtc ggtactgcat tcagaagatg cgctcgaagg accgcaggca tttgccgaaa
    13681 aacgcgctcc ggtgtggaaa ggtcgttaat gtgactatgc cggatggcgc ttcgcttatc
    13741 cggcctacaa cacatgcaca accgtaggcc ggataaggta tttacgccgc catccgacaa
    13801 aaaaaaaccg aggtacaacc atgagctatt acgcctttga aggactgatc ccggtggtgc
    13861 atccggacgc gtttgtccat cccagcgccg tgctgattgg cgatgtcatc gtgggcgccg
    13921 gtgtttatat tggcccactc gcgtcattgc gtggggatta tggtcgcctg atcctggagg
    13981 caggctctaa tctgcaggat ggctgcatta tgcatggcta ctgcgatacc gataccatcg
    14041 tgcatgaaaa cggccatatc ggccacggcg ctattctaca tggctgcgtg gtgggacggg
    14101 atgccctggt cggcatgaat agcgtcatta tggacggcgc agtgattggc gaagagagca
    14161 ttgtcgccgc catgagtttt gtcaaagccg gatttcaggg tgaggcaagg caactgctgg
    14221 tgggatcacc ggcgcgcgta ctacgccagg ttacggacca ggagctgcac tggaaacgcc
    14281 tcaataccaa agaatatcag gatcttgcga tccgttgtcg aacggggtta tctgaaacga
    14341 agccgttaac gcaggtcgaa gaaaaccgac cgcgcctgaa aggcacgacg gacgtgaagc
    14401 caaaatcagc acagtaattg atgccggatg cgctcacgct tatccggcct acgcgtcaat
    14461 taccgtttac cccgccagca ggttaaacag acaattagcg acgcatactc ttggagagca
    14521 tcatctgcca tttctgctca cggtttagct ctgtgggggg aacggcagac agccgcggcg
    14581 ctttcgccac gctcactttt ctttcctgca aattatgatt caatcggcga tagagttgag
    14641 agtcgatact cacgactttc accagacgct ggcactggca gcctcgtcct gcaatttggt
    14701 tagggatcat cttcacttca caaacaattt cccccacttc tgacagaata taggagagcg
    14761 tattaattgc tttgcaatgt tcaatatcaa attgacggga aatctccctg gcagtgatcc
    14821 atcggttctc tgccatcatc cagtcagcaa ttaacaaata aagcggtctt tcaacatatt
    14881 tttcacacat aagcacacca tttcacaaat taaaaatctg gctacggcct gtccaaacta
    14941 ataaaaacta agccatatta aaattgtgga tatgaaagat agtatgcgac ttaaatattg
    15001 attagtgtga gcaatatcgt gcttattaca ttgaaaatgt ggttacggaa acggacttct
    15061 ccaggaatga ccttacgcaa gataaaaaaa gggtttcttt acagaaaccc tttcaacatt
    15121 atattacagg ttcggttaga gcaatatccg ccgccccctt ggtttacgac tttttgatct
    15181 gcgcgtgcat ttcctgcacc gaggttacct tctcggtggc atcggcattg agcgccatcg
    15241 tcgtggcaaa accgccgttc agcgtggtgt cataatgcac cttatactgc aacgcgctgc
    15301 ggcgaatcac ccttgagtct tcaatcgccc ggcggcctgc ggtggtgttg atgatgtagg
    15361 tatattcgcc attcttgatg cggtcctgaa tgtgcggacg accttcgtgc accttgttca
    15421 ccagacgcgg gttgataccg gcttcgccca gcacaatcgc cgtaccgtgg gtggcatcca
    15481 gctcgaagcc ttgtttcagc agcttagcgg ccaggtccac cacgcgctct ttgtcgcctt
    15541 cgcgaaccga gagcaacgca cggccctgtt tcttcatagt ggagttactg cccagctgtg
    15601 ccttggcgaa cgcttccgcg aaggtacggc ccacgcccat cacttccccg gtggagcgca
    15661 tttctggccc taacagcggg tcaacgcccg ggaatttgtt gaacggcagt accacttctt
    15721 tcaccgagta gtacggcggg ataatttctt gagtcacgcc ctgctcggtc agcgatttgc
    15781 cggccatcac gcgcgccgcc actttcgcca gcggcacgcc ggtggctttg gagacgaacg
    15841 gcacagtacg cgccgcacgc gggttgactt caatcaggta gacttcgttg tctttcaccg
    15901 caaactgcac gttcatcagg ccgcgcacct gcaactcgaa ggccagcttc tgcacctgct
    15961 ggcgcatcac atcctgaatt tcctggctta gcgtgtaggc cggcagagaa caggcggagt
    16021 cgccggagtg tacgcccgcc tgctcgatgt gctccatgat accgccaatc agcaccattt
    16081 cgccgtcgca gatagcgtcc acgtccactt caaccgcgtc atcaaggaag cgatccagca
    16141 gcaccggcgc atcgttagag acgctgaccg ccgtctggaa gtagcgacgc agatcggctt
    16201 cgtcatagac aatttccatc gcccggccgc ccagcacgta agaaggacgc accaccagcg
    16261 ggtagccgat ctctttcgct ttttcgacag cctgttcaat ggcggtgacg gtggcgttgg
    16321 ccggttgctt cagcttcaga cggtcaaccg cgtgctggaa gcgctcgcgg tcttccgcgc
    16381 ggtcgatggc gtccgggctg gtgccgataa ccggcacgcc tgccgcttcc agcgcgcgcg
    16441 ccagctttag cggggtctgg ccgccgtact gcacgataac gcctttcggc ttctcgatac
    16501 gcacgatttc cagcacgtct tccagcgtca ccggctcgaa gtacaggcgg tcggaagtgt
    16561 cgtagtcggt agagacggtt tccgggttac agttgaccat gatggtctcg taaccgtctt
    16621 cgcgcagcgc cagcgaggcg tgtacgcagc agtagtcaaa ctcaatgccc tggccgatac
    16681 ggttcgggcc gccgccgagg accatgattt tatcgcggtc aacggacggg ttcgcttcgc
    16741 actcatcttc ataagtggag tacatatagg cggtgtcggt ggcgaattcc gccgcgcagg
    16801 tatccacacg cttgtagacc gggtgcaggt catactggtc gcgcagctta cggatttccc
    16861 cctcgcgcac gcccgccaat tttgccagac gcgcatcggc aaaaccttta cgcttgagct
    16921 gacgcaggaa gtcggcgttg aggccagtaa tcccgacttc agttactttc tcttccagac
    16981 gcaccagctc ttcaatttgc accaggaacc agcggtcgat gttggtcagg ttgaacacgc
    17041 cgtcgacgga gaggcctgcg cggaaggcat cggcgatata ccagatacga tctgcgcccg
    17101 catctttcag ctcgcggcgg attttggtca gcgcttccgg gtcgtcgagg ctgactttcg
    17161 ggtcgaagcc ggtggcgccg acttccaggc cgcgcagcgc tttttgcagg gattcctgct
    17221 gcgtgcggcc aatcgccatc acttctccga ccgatttcat ctgggtggtc agacggtcgt
    17281 tggcaccggc gaatttctcg aagttaaagc gcggaatttt ggtcacaacg tagtcgatgg
    17341 acggctcgaa ggaggccgga gtacgcccgc cggtgatgtc gttcatcagt tcgtcaaggg
    17401 tgtaacctac cgccagtttg gcggccactt tggcaatcgg gaaaccggtg gctttcgacg
    17461 ccagcgccga ggagcgggag acgcgcgggt tcatttcgat aacgatcaga cgaccgtttt
    17521 tcgggttcac tgcgaactgg acgttagaac cgccggtttc gacgccgatt tcacgcagta
    17581 ccgccatcga ggcgttacgc atgatttgat attctttgtc ggtcagagtc tgggcgggcg
    17641 ccacggtgat cgagtcccca gtatggatac ccatcgcatc gaaattttcg atagagcaga
    17701 cgatgatgca gttgtcgttt ttatcacgca ccacttccat ctcgtactct ttccagccga
    17761 tcagcgattc atcaatcagc aattcgttgg ttggcgagag atccagaccg cgttcgcaga
    17821 tttcttcgaa ctcttcacgg ttgtaagcga taccgccgcc ggtgccgccc atggtaaagc
    17881 taggccggat gatgcacggg aagcccacgt cagcggcaac cgccagcgct tcttccatgg
    17941 tgtgcgcgat accggaacgc gcggtgtcga gaccaatttt cttcatggcg atatcgaagc
    18001 gacgacggtc ttcggcttta tcaatggcgt cggcggtggc gccaatcatg gtgacgccga
    18061 actcttcgag cacgccctgc cgctccaact ccagcgcgca gttcagcgcg gtctggccgc
    18121 ccatggtcgg cagcaccgca tccggacgct ctttttcgat gattttgcgc accacttccc
    18181 agtgaatcgg ctcgatgtag gtggcatcgg ccatttccgg gtcggtcatg atggtggccg
    18241 ggttagagtt caccagaata acgcggtagc cttcttcgcg cagcgcttta cacgcctgag
    18301 cgccggagta gtcaaactca cacgcctgac cgataacaat cgggcccgcg cccagaatca
    18361 ggatgctttt tatatctgta cgttttggca ttttgttggc tcctgattat tttgctgaag
    18421 aacggtagtg cttaatcaat tcgataaagt ggtcgaacag cggcgccgca tcgtgcgggc
    18481 ccgggctcgc ctccgggtgt ccctggaagc tgaacgccgg tttgtcggta cggtgaatgc
    18541 cctgcagggt gccgtcgaac agcgacttgt gggtcacgcg caggttggcg ggcagcgagt
    18601 cttcatccac cgcaaatccg tggttctgcg cggtgatcat caccacgttt ctgtccatat
    18661 cttttaccgg atggttgccg ccgtgatggc cgaacttcat cttaacggtc ttcgcaccgc
    18721 tcgccagcgc cagcagttga tggccgaggc agatgccgaa cacaggaatg tcggtctgga
    18781 ggaatttctt aatcgcctcg atggcgtagt cgcacggcgc cgggtcgcca gggccgttcg
    18841 acaggaagat gccgtccgga ttcattttca gcacctcttc agcagaggtt tgcgctggca
    18901 ccaccgtcag gcggcagccg cgatccacca gcatacgtag aatgttgcgc ttggcgccaa
    18961 aatcgtaggc caccacgtgg aacggcaggt catcctcaga tttcgcttcc ggtaaaccgt
    19021 ctttcagcgt ccagctaccc tgcgtccagc ggtaagtttc cgccgtggtc acttctttcg
    19081 ccagatccat accgttcagt ccaggaaatg ctttcgcttt ttccagcgcc agcttcgcat
    19141 ccgggctatc gcctgcaatg atgcagccgt tctgtgcgcc tttctcacgc agcagtcggg
    19201 tcagcttgcg ggtatcgata tcggcaatcg ccacgatgtt atggcgtttc aggtaagaag
    19261 agaggtcttc ggtgttacgg aagttgctgg caatcaacgg cagatcgcga atcactaaac
    19321 cttgcgcatg aacctgagaa gattcttcat cggcttcatt ggtgccgaca ttaccaatat
    19381 ggggataagt aagagtgacg atttggcggg aataggaagg atcagtgagg atttcttgat
    19441 aaccggtcat tgaagtattg aaaacgactt ccccaaccgc cgaacctgtt gcccctatgg
    19501 cccgaccgtg aaactgggtt ccgtcttcca gaaccaatag cgctgactta atcaaaacac
    19561 cctccagaga atattcactc actttatttg catatcaatt cattcagtca gtatgaagca
    19621 atgcaaattt gcttacccgt ggatttctgg caaacggcgg cattctgaag ttaagccgga
    19681 taaaagtcaa cttaaagcgg gtatttttta tgttattttg cacattataa ggaagttatt
    19741 ctgtttaata ggcaaaaaga tcaactaagt gacgatagaa aacgcttgcg cttccttgag
    19801 ttcgcaaaaa actggctgcc atgataaaaa gtggaccaaa tggtcaaatt tcacattaaa
    19861 acaacaaaaa acaacgataa aaattcattt aatagtcatt aatgtcatta aatgcataaa
    19921 aattcaaaat aaatcaaatt aacaacaaaa acattttaaa aatcaatacc ttaaaaatat
    19981 aaaaaacaaa tcaaatgcat cataaaatca acaaaaaaca gcaaattaag actatataat
    20041 gataactcca atttcgatat taatatctaa cttctttttc tttaagacag gcgcatacga
    20101 ttggaccaca aacagcctca ctacagcata aaaaagctaa cttattgaag caaaagagat
    20161 aaaacgatcc cgtggaacag cactaacccc ccaatggata tcagtcttat cagtctggtc
    20221 gaggtgcctt ttgcatacgg taagccactg cggcagaaca tgtcgtggga gaagaaactg
    20281 tcgaaacatg aatggtgaaa ggcgttattt atctgaccga ataaccgagg ggcaaaaaca
    20341 aaagggcaat aatatattgc cctttgtaat caattaatct tgattaccac aaccacatca
    20401 cgaaggtatt tagtcgctat aatacatcca gccccagcac atcccgcatg tcaaatagcc
    20461 catttttctt cgtttttagc cataacgccg atcgcaacgc gccatttgca aacgtcatgc
    20521 ggctggaagc tttatgcgta atctctacgc gctcgccaat atcggcaaac atcgcggtat
    20581 gttcgccgac gatgtcgccc gcccgaacgg ttgcaaagcc aatcgttccc ggtacgcgct
    20641 cgccggtata accttcacgc gagtagaccg cgcagtcctt cagatcttta tccagcgccc
    20701 cggcgattgc ctcgcccatt gccagcgctg tccccgacgg tgcatccact ttatggcggt
    20761 ggtgcgcttc aataatttca atatcgctat agtcgcccat taccttcgcg gctttctcca
    20821 gcagcttgag catgacgtta acgccgacgc taaagtttgc ggcgaaaacg atcgcaatct
    20881 cttgcgacgc ctcacgaatg gcctgtttac cggcgtcgtc aaagccggta gtaccaatca
    20941 ccatcccttt accatgctgg cggcaaaacg ccagatgcgt caacgtgcct tccggacggg
    21001 taaaatcgat gaaaacgtca aaatcatctt ttaccgcctc aaggctgctt tgaacgatca
    21061 cgccggactt tcccgccccc gccagttcgc cagcatcgct gcccagcaag gaagagcctt
    21121 cgcgctccag cgcggcaccc agctgaacac cttccatcgc catggcggcc tggattaact
    21181 gccgtcccat gcggccaccg gcgccggcaa tggcgacgcg gatttgtgct tcatgcatag
    21241 ctattctctt ttgtaaaaat tgcgtaaacc gttttcagag taaccagcgc gcccggaggc
    21301 cgccatctaa aatcgccgat aattagaaat taatgataaa cagggagcga tatcagtaaa
    21361 agacatgatt catcccacag gatgaatcat tgctggagag aatgaaagaa gagaaactta
    21421 ctcaggatag agggaaccgg caggaaaatg acttaaaaac caggtcactg ccagtaaatc
    21481 cgcgctaccg ccagggctta agttacgcag gatgagttca tcatcgagga actgcatcgc
    21541 ttcaatgccc ccctcaacca atacgccccc ttgccacaac aatttttgtg cctgctgctg
    21601 cacgtagtaa agcccttcca ggcctccccg tgacaccaga ttggtatcat cattccacgc
    21661 catcagatgc aacaatgttt gcagcagggc aagatgggta tcgtcatgct cctgcacgac
    21721 ccggttaaac accggcaaag cctgcgttct gacggttcga aaaccgcttt ccgcttctcc
    21781 ccgcgcgccc gacaggccat aacactggaa atgggtttca ctctttgtca gttttcccgc
    21841 ttttcttgct gagagctcgt gggcaacaat attccgactc aggcgagcaa cctggtcgca
    21901 gatacgattt tgctccaacg gttctccccg cgcgagaagt cggccaatcg ctgcgctcag
    21961 caggccaaaa gcgaaaatcg ccccgcgatg ggtattcaca ccattggtcg cctgtagcat
    22021 atcgttctca caggccatcc ccagcggacg cagcatcacc aggacatttt ctgccgccag
    22081 cgccgccgtg ttgttgccca tgataaaaaa cttttccatc cacggagcaa tggcggtagt
    22141 gctacgttca aatgccgcca gatccatatc cctatgcgct cccgaattac gaatatcgac
    22201 cagaccgggt tttggtgtca gcctggcttc cgtcagcagc gctcttgcaa ccaacccatt
    22261 aagttcgcca gccgccagcg atgagtacgc tggcgtacgc cgttcagtca caacgctcac
    22321 gttcatagca ttcaatcctt cgtgcaattt catccaacaa aaggtcaagg gtgtgatgct
    22381 tgccccgggc acagagatga gcatcctgct ggcatatcaa acatggccgg gcaggatgcc
    22441 cgagttcacg gcgtgatagc gacttaccgt cgctatcaat aatgtcgatg tcccaaagcc
    22501 gccctaacgg atggctcatc tctagtgtcg acatgtgctg tttcaacgcc attgccggcg
    22561 cacagaccgc tgccatccat tccgggccgc tgcgttcatt tacctgcatt tcccagacgt
    22621 tgacccactc cttctgttcg caaagcgcca gtatttcggc aattgcgtaa tcggcgacac
    22681 gccgccagac cgctgagttt ttaacggcgc ccggtgcaac cagcgtgagg gaaatcaacg
    22741 gtagccgata gcagttcaac gcctgacgct gcctggcggc acgtttatcg cgcgcttgta
    22801 gcatctcctc cagcgtaact gcctggccct ggtacagcag gtctgtgccc ttcatcagcc
    22861 tttaacctgg cgaatcacgt caatcactga accgtcgcga taacgcacca cagccaccac
    22921 ccgatcggta aactcaatcg gctgcggttt accggtcagt tgctcggcgc gctgttgcag
    22981 ttgttcgatg gtcatcagcg ccacgcccgc agcacgcagg ttatcaagca gatcctgacg
    23041 cgcagggttc accgcaatac catggtcggt aaccagcaca tcaacgcttg cccctagcgt
    23101 gacggtagtc agcacttttt ctaccacgca aggaatacgc ccgcgcacca gcggtgcggt
    23161 aataatggtg agatcggccc ctgctgccgt atcgctatgg ccgcccgatg cgccacacag
    23221 tacgccgttt gaaccggtca tcacgttaac gttgaaattc acgtcaattt ccagcgcgct
    23281 cagcatcacc acattcaggc gttcgcatgc cgcgccttta gagccggggt tcgcgtattg
    23341 attggttgaa atttcaatat gatgcgggtt ctgcgccagc gaacgggctg catcgccatc
    23401 gaatgattgc gtatccagca gcgctttgat caaccctttc tcatgcagat ccaccatggt
    23461 gccggtgatc ccgcccaggc caaaactcgc cgtaatgttg tggcgacgca ttttgtcttc
    23521 caggaaacgg gtgaccgcca gagaagcgcc accggtgccg gtttgcagcg agaaaccgtc
    23581 acaaaaataa cccgagtgtt cgatcacatt ggccgcctgc cgggcgatca acagttcacg
    23641 cgggttgctg gacagacgaa tcgcgcccgc agtgattttt tccggatccc ctacttcgtc
    23701 cacctgtacg atcaaatcaa cctgatcctg cgcgatactg gccggataat tggggaactc
    23761 gacccactct tcagtcagga gcaccacaca tttagcgtac tgcgcatcaa cctgcgcata
    23821 ccccaaagag ccgcagcgtg acttgccgct aaaaccgttc gcattaccaa attcgtcgca
    23881 gcacggcacg ccgaggaaag cgacatcaat attcagctca ccgctctgaa tcagttttac
    23941 gcggccgccg tgagagtgga tctgtaccgg gttttccatc aggccagcgg agatctcttc
    24001 ccctaacttg ccgcgcagcc cagaggtgta aatctgccgc accacgccat ttttaatgtg
    24061 ttcgataagc ggccagtggg catcgattaa cgagctggag gcaagcgtca gatcgcggaa
    24121 tcccatttcc gccagtttcg ccatcaccat attgacaact ttgtcgccac cacgaaacgc
    24181 atggtggaag gatatcgtca tgccattttt aagcccggaa cgacggatag cctcttcaag
    24241 cgagtcacaa attttacgcc gacgcttttc cgtttcactg gcaagccacg ggctattcac
    24301 tgttaccccc tggtagggtt gtaatccttc cggtacgaca tattgctgat tgagcatagt
    24361 tacagtctct ttcatggttc cttccttaat cacgaatacc ggaagccgac agcgccacca
    24421 ctttgcgcgc gtggtcgata atcgggccgt caatcatttt gccgttgagt gaaacgacgc
    24481 ccagaccgcg agactcagcc tcttcagcgg cggcaatcac ctcgtgcgca tgctcaactt
    24541 ctttacgcgt cggagaataa gcctgatgta acagctcaat ctgacgtgga ttcactaagg
    24601 acttaccgtt aaaaccaagc cctttcgcca actgcacttc cttcaggaag ccttcttcat
    24661 tattgatatc cgaccaaacg acatcatagg cggcaatacc cgcaacgcgc gccgcatgca
    24721 gcactgcgca gcgggcgtag aacagctcgg tgccatcgcc ccggctggtg cccatatcca
    24781 tcacgtaatc aaatgccgcc agcgcaattg ccaccatgcg cgggctggag gtggcgatgt
    24841 cgacggcatt gaccacgcct ttcgctgatt cgatcgccgc catcagcctg gtactgccga
    24901 cttcacgtcc acattcacgt tcgatccgtt caacctgcgc ttccagctcc agcacatcgt
    24961 ttttgctgtc ggttttcggc agacgcacga tatccgcgcc accacgcacg acggcctcaa
    25021 gatcggccag accgaatggc gtgttcagtg gattaatgcg caccactttt tcaacatcct
    25081 gatagaacgg atgttgaagc gcgtgatgga ctaaaagacg ggcggtatct ttctcacgta
    25141 atgctacggc gtcttctaag tcgaacatca ccgcgtccgc accatagaca aacgaggtgc
    25201 tcaacatggc cgcatttgcg ccggggataa acaacatact gcgacgaggt ctcataacgc
    25261 actccattga atttccgttt gttctgcagc gcgtaacgcc gccgcctgca ctcgggcgcg
    25321 taaaatacac tccagcgcgc ctttgtcatc gacgctaacc agcgcgcgtt caacgcccag
    25381 cttcgccagc gtttcccgaa ccacctgctc aatcgccgcg ccaaactgct gcttcaccag
    25441 actctctagc tccagccgaa ttcctggctc gctggatgga ccaatcctga tcatcacatc
    25501 gctggattcc agcgtgcctg ccagggcatc tttaatgatt ttcattagtt atgttccttg
    25561 ttaacggtgt tacgtcatat ggtttcagtg tgtctggcgg catgccgctg cagatatgcc
    25621 agggtgccag caggcaccag cgcgcttatt gccggccaat tacgttcgct atacagtttt
    25681 ctgacgcgag aggcggaaat agccgtgccg tttttctcca cccgcgccag ctcgacgacc
    25741 tcaataaccg ggccgctgcg cttcggatcg tgtaaaatgt cgtgcatccg ctggttatag
    25801 gcacaggtca gaggacaaaa cggctcactg ccgacaaaac gatgggtaat ccccagcgct
    25861 ggagccagat gttcacggaa gagttgcaga tcgatctggc aatggcagtc gtccacaacc
    25921 cctttttctt tgaggaaata gccgggaaac gtcgcacgcg agatcatata agcggagccg
    25981 gaatgcaacg tgacgttgtc aatgcccgcg attccttgtt cgatcagcgc ccaacggtcg
    26041 gtataggaaa aaaatgaagc atcttctttg actacaaaca gatgcaacca gtcacaggcc
    26101 gcagccgctt gctccaccag ataacggtgg cccaaggtaa acggattggc gttcatgaca
    26161 atggcgccga tcgtttttcc cggttgacga taaagcgcca gttggcgaca aaagcgcgct
    26221 aaccgttcac tgctgttctc cattaacacc gccagctcac ctgcctgcgc aatgggccaa
    26281 aaccccgcgc cagaaaacag caaccgattt tgcggcttag tgaacaggaa aagctcgctg
    26341 cggtttaact cgtaggccaa tgtaagcagc tcagtcagca gtttgaggct gagcccttcc
    26401 ccttgtaaaa ccggggaaac ggcgatgcat ttcagtacgt ttccggccag cgagccgcat
    26461 ccaactatct caccctgcca atatgcgcat accgcgattt cacaatcatc ttccagggcg
    26521 agtcccacgc cctccagaaa catggcgacc gactcgcgac gcaatacatc cttttgcaaa
    26581 taaatgcgtt taaatattag attcactcta ttctgcatcc gtcagcaaat aacgttgcat
    26641 atttcgccag cgtttgtatt actcgtctgg aatagacatc acactttccc ccttgctttt
    26701 ataagcttta tggtttttat ttccttaatt aaccagagtt aataaaaata attaaattaa
    26761 ttaaaaacac aaccattcag tgaagatagt cacatctcac ggttcattga atttattagt
    26821 atgcgcgggt cttgttaccc atcaatacac aggaaaatgt ttatgaccaa catgacccag
    26881 gcttcggcga cggagaaaaa gggggccagc gatttactca gattcaaaat ctttggtatg
    26941 ccgctaccgc tttatgcctt tgcattaatt actttattac tgtctcattt ctataatgct
    27001 ataccgactg acttagtcgg tggttttgct cttatgtttg ttatgggggc catttttggt
    27061 gaaatcggca aacgtttacc gatcttcaat aaatatattg gcggcgcacc ggttatgata
    27121 tttctggttg cagcttattt tgtctatgct ggcatattta cgcagaaaga aattgatgcg
    27181 atcagcaacg taatggataa aagcaacttc cttaacctgt ttatcgcagt gttgatcaca
    27241 ggcgcgatcc tgtcggtaaa ccgtaagctg ctattaaaat cactgctggg ctatatccca
    27301 accatcctcg ccgggattgt cggcgcgtcc cttttcggta tcgtcattgg tttgtgcttc
    27361 ggtatcccgg tcgaccgtat catgatgcta tacgttctgc cgattatggg cggtggtaac
    27421 ggcgcaggcg ccgtgcctct gtctgaaatt tatcactcgg ttaccggacg ttctcgcgaa
    27481 gagtattact caacggctat tgctattctg accattgcga atatcttcgc cattattttc
    27541 gccgccctcc tcgatatgat aggcaaaaaa tacacctggc ttagcggtga aggtgaattg
    27601 gttcgtaagg cttccttcaa aaccgaagat gatgaaaagg ccggtcagat tacccatcgt
    27661 gaaacggcgg ttggcatggt gttatccacc acctgcttcc tgctggccta tgttgttgcc
    27721 aagaaaattc tgccaagcat cggcggcgtc tctattcact acttcgcctg gatggtcctg
    27781 attgttgctg cgctgaacgc atcaggtctt tgctcaccgg agattaaagc cggggcgaaa
    27841 cgtctttctg acttcttctc caaacaactg ctgtgggtgc tgatggtagg tgtgggtgtt
    27901 tgctacaccg atctgcaaga gatcatcgat gccctgacgt tcgcgaacgt cgttatcgcc
    27961 gcgatcattg tggtcggcgc tgtcgttggc gcagctatcg ggggctggtt gattggcttc
    28021 tacccgattg aatcatccat tactgcgggt ctttgtatgg ccaaccgcgg cggctccggc
    28081 gatctggaag tgctctccgc ctgtaaccgt atgaacctca tttcatatgc acaaatttcc
    28141 tctcgtctgg gcggcggtat tgtgctggtt atcgctagca tcgtgttcag catgatggtg
    28201 taaaaaaacg cacggcggtg tctttgccgc aaacgacctg gagaaaagta gaggccaaag
    28261 ccagaggtgg ccaagggaaa tccactctac tccttagccg gattcaccag gaaggttgtc
    28321 gtcaaggcca ccgtcgtgcc tctcattatg gaaaatgatt catgaatgaa gctgtattac
    28381 tgggtgaagg tttcaccctg atgtttttag ggatggggtt cgtactgagc tttctgttcc
    28441 tgctgatctt tgccattcgc ggtatgtctg ccgtgattac tcgcttcttc ccggaacccg
    28501 tcgccgcgcc cgcaccgcgc gccgttcccg ccgtggacga cttcacccgc ttaaagccgg
    28561 tgattgccgc cgccattcac catcaccgcc ttaacgctta attcccggag ggatccatga
    28621 ctattgccat taccgacgtc gtcctgcgtg acgcccacca gtctctgttc gccacccgcc
    28681 tgcgccttga cgatatgctg ccgattgccg ctcagctcga cgacgtgggc tacggctcgc
    28741 tggagtgctg gggcggcgcc acctttgacg cctgtattcg ttttctcggc gaagacccgt
    28801 ggctgcgcct gcgcgaactc aaaaaagcca tgcccaaaac cccgctgcag atgctgctgc
    28861 gcggccagaa cctgctcggc taccgccact acgccgatga tgtggtggag cgcttcgttg
    28921 aacgcgcggt gaaaaacggc atggatgtgt tccgcgtctt cgatgccatg aacgacccgc
    28981 gcaatatgaa agccgccctg caggcggtgc gcagccacgg cgcgcacgcc caggggacgc
    29041 tctcctacac caccagcccg gcgcacaccc tgcagacctg gctggacctg accgaacagt
    29101 tgttagagac cggcgttgac tcgattgcca tcaaggatat gtccggcatt ctcacgccga
    29161 tggccgcttt tgagctggtg agcgaaatca aaaaacgttt tgaggtgcgc ctgcacctgc
    29221 actgtcacgc caccaccggg atggcggaga tggccctgct gaaggctatc gaggcgggtg
    29281 ttgacggcgt ggacacggcg atttcgtcca tgagcgccac ctacggccac ccggccaccg
    29341 aggcgctggt ggcgacgttg gcaggtactg agcacgacac cgggctggat atcctgaagc
    29401 tggaaaatat cgccgcgtac ttccgcgagg tgcgcaaaaa gtaccatgcc tttgaaggcc
    29461 agctgaaagg ctacgacagc cgtattctgg tggcgcaggt accgggcggg atgctgacca
    29521 acctcgaaag ccagctgaag cagcagaacg cggcggacag gctggaccag gtgctggcgg
    29581 aaatcccccg cgtgcgcgag gacctcggct ttatcccgct ggtcaccccg acctcgcaga
    29641 ttgtcggcac ccaggcggtg ctcaacgtcc tgaccggcga acgctacaaa accatcgcga
    29701 aggaaaccgc cggcattctg aaaggcgaat acggccacac cccggtgccg gttaacgccg
    29761 cgttacaggc ccgcgtgctg gaagggagcg ctccggtgac ctgccgcccg gcggacctgc
    29821 tgaagccgga gctggctgaa ctggaagcgg acgtcaggcg ccaggcgcag gagaagggga
    29881 ttactctggc gggaaacgcc atcgacgacg tgctcaccgt ggcgctgttc ccgcaaatcg
    29941 gcctcaaatt ccttgagaac cgccataacc cggcggcgtt tgagccactg ccgcaggcgg
    30001 aagccgcgca gccggtggca aaagcagaga agcctgccgc ctccggtatc tacaccgtgg
    30061 aagtggaagg caaagccttt gtggtgaggg tcagcgacgg cggcgatatc agccagctta
    30121 ctacggctgt tccggcggcc tcttccgcac cggttcaggc tgccgccccg gcaggcgccg
    30181 gcaccccggt caccgcgccg ctggcgggca acatctggaa ggtgattgcc accgaaggcc
    30241 agagcgtggc cgaaggcgac gtgctgctga ttctggaagc catgaagatg gaaaccgaaa
    30301 tccgcgccgc gcaggccggc accgtccgcg gtatcgcggt gaagtccggg gacgccgtct
    30361 ccgtgggcga caccctgatg acgctggcgt aacggagaac tgaaatggaa agtctgaacg
    30421 ccctgcttca gggcatgggg ctgatgcacc ttggcgcggg ccaggccatc atgctgctgg
    30481 tcagcctgct gttgctgtgg ctggcgatag cgaaaaagtt cgaaccgtta ctgctgctgc
    30541 cgataggctt cggcggcctg ctctccaaca tcccggaagc gggcatggcg ctgaccgcgc
    30601 tggagagcct gctggcccat cacgacgccg ggcagctggc ggtgattgcc gcgaagctca
    30661 actgcgcgcc ggacgtgcac gccatcaagg aagcgctggc gctggccctg ccgtcagtcc
    30721 agaaccagat ggaaaatctg gcggtggaca tgggctacac gccgggggtg ctggcgctgt
    30781 tctataaagt ggcgattggc tccggcgtcg cgccgctggt catctttatg ggcgtcggcg
    30841 cgatgaccga cttcggcccg ctgctggcca atccgcgcac cctgctgctg ggggcggcgg
    30901 cacagttcgg catcttcgcc accgtactgg gggcgctgac gctgaactac ttcggcctga
    30961 ttgccttcac cctgccgcag gcggcggcca tcggcattat cggcggcgcg gacggcccga
    31021 cggcgattta tctgtcgggc aagctggcac cggagctgct gggggccatt gcggtggcgg
    31081 cctactcgta tatggcgctg gtgccgttaa tccagccgcc gattatgcgc gcgctgacca
    31141 gcgagaaaga gcgcaaaatc cgcatggtgc agctgcgcac ggtgagtaag cgggaaaaaa
    31201 tcctctttcc ggtggtgctg ttactgctgg tggccctgct gctgccggac gccgcgccgc
    31261 tgctggggat gttctgcttc ggcaatctga tgcgtgaaag cggggtggtg gagcgtctga
    31321 gcgacacggt gcagaacggt ctgattaata tcgtgaccat tttcctcggg ctgtcggtgg
    31381 gcgcgaagct ggtcgcggat aagttcctgc agccgcagac gctgggcatt ctgctgctgg
    31441 gggtgattgc ctttggtatc gggacggcgg ccggggtgct gatggcgaag ctgctgaacc
    31501 tgtgcagtaa gaacaaaatc aacccgctga taggttcagc cggggtgtcg gcagtgccga
    31561 tggcagccag ggtgtcgaac aaggtgggcc tggagtcgaa cccgcagaac ttcctgctga
    31621 tgcacgcgat ggggccgaac gtggccgggg ttatcggttc ggccattgcg gcgggcgtga
    31681 tgctgaagta cgtgctggca atgtaatcca attctaatcg ggagcagtga ttatgctccc
    31741 gcaaaatgag gacacagtaa tgagtgaaat ggttgcgttt cggcaaggta catccatgcc
    31801 atccagagaa accatcttgc gttatgttgt tgagacggtg aatcagataa ctgagcttga
    31861 gccagcgctg catttgctgc cgtggtccgg cgtcaactca gcaatatatg agcaacgttt
    31921 tgcacagtgt tacgacgagg ggctttgtgc cgcacagacg tcggcaccga atgttccgca
    31981 ggggattctg ccatcgaccg attgggctca gggtatcggg ttactctgtt tcgccgcagg
    32041 gtatatgagc gcaggcgagc ggccattaac acacaatcgg ttatgcgatt tcgtcaaaca
    32101 ggcggctgtt ggtttatcgc cgattgaggg ggaggcggcg agcggtttct cgacggtgcg
    32161 tagtattgca ttacccgtat tcaggcgatt acaacgcgat ggtcacgcgt ctcgggtcct
    32221 gctgttacaa acgttgctgc atctggtcgc ctggaaaagc gcatcgcagt atgcgcgtca
    32281 acaggcgcaa cgactgctct ggatgggcgg cattctgggg gaagggagcg agtctggctt
    32341 attgacactc gataaggcgc tgcgtgaaga ggccgtcggg gaaaagagtt tccccgctct
    32401 gctaatcttc acgagtttcc tggcgcattt tccggcaggg ccagtcttta ttgactagcc
    32461 gtcgaacgac gcaggcaaaa gctgcgtcgt tttagtttga cgccgggtat tcctgcaccg
    32521 tcacctggaa cgtgagctgc ttatcatccc gcattaccac gaccggaatg acggagcccg
    32581 ggcgaatttc cgccacctga tccatcgtct ccagcgcgga cacggcgggt ttattattga
    32641 ccgaaataat caaatcatta acctgaatac cggcaagcgc agcggggccg tttggcgtta
    32701 cttcattaac gacaatgccc tgaatcgggt ccatgccgct accctgctgc gcgtgcagcg
    32761 gcgcgatttc tcgtccgcca ataccgatat agccgcgaat cacgcgaccg tcgcggataa
    32821 gcttatccat aattttcgtg gctagctgga agggaatcgc aaaaccaagg ccttccggcg
    32881 tttcgccatc gttactctta tcaaaagaga gggtgttgat ccccatcagt tcgcctaacg
    32941 agttgaccag cgcgccgccg gaattaccgt ggttaatcga ggcgtcggtc tggagaaaat
    33001 tctgtcgccc cgtcgggttc aggccgatac gacccgttgc gctgatgatc ccctgggtga
    33061 tggtctgtcc cagattatat gggttgccga tagccagtac gacgtcgcca atatgcggtg
    33121 tacgctttgt attaatcggg atggtaggca gcccgccagt ggcgttgatc ttcagcaccg
    33181 ccaggtcggt aagcgaatcg gagccaacca gtagcgcttc aaagacgcgg ccatcctgta
    33241 gcgcgacgat aatctgatcg gcatcgttaa tcacgtgctt gttggtaata atataaccgc
    33301 gttgatccat gatcacgccg gaacccagcg tgcggatctc cagttgatta tgcgcggtac
    33361 tgttcatact gcggttatag acattgacga cggcaggcgc ggcgcggcga accgcaaaat
    33421 tataactggc tggcgtctca tcggtactgt cgaattgcgg gacggcgata ggattaattt
    33481 tgcgcaaaga aggcatgacg gccaacagaa tagcgccgac aattaaacct attgcgaccg
    33541 aacgtaagag cttcacaaac atgatggagg cgtcgttaaa aaagggaacg gcagcagcat
    33601 accatgagtt aaccggacat cacatcgcag gctgatgccc ggtttaagac aggattagcg
    33661 cagcaataga taaatgttct cgttgccgcg tactacctga agagcaatga tggacggttt
    33721 tgccgccatc actttgcgca tttcggcgat agaactgatg cgatcgcgat taacgccgat
    33781 gataacatca tctttttgca aaccggcctg cgcggcagga ctgctttttt cgacgctatc
    33841 aaccttaacg cctttcgtcc cgtctttcag ctggccgtcg ctcaacgtcg cgccttgcaa
    33901 cgccggggcg atcatttcgg cgctggcgga agaagaggta ttggaatcca gcgtgacttc
    33961 cacctccagc ggcttaccat cgcgcagcag gcccagcttc actttcgtgc ccggttcggt
    34021 ggtggcgata cgtgaacgca gttcggcaaa gctattcagc ggcttaccgt taagactgat
    34081 aatcacgtct ccggatttca ccccggcctt cgccgaacct gaattgggta aaacctcgct
    34141 gacaaaagcg ccacgctgaa cgttcagttt gaatgcctta gcgatatcag cggtcatttc
    34201 agtgccttta attcccagca atccgcgttt gatttcgccg aactgaatca actgctgcgc
    34261 cagcgtctgc gccatattgg aaggaatagc aaagccaatg ccgatgctcc cgccccctgg
    34321 cgcgaggatt gcggtattaa tcccgatcag ctcgccgttc aggttaagca gcgcgccgcc
    34381 ggagttgccg cggttaatag aggcatcggt ttgaataaag ttctcaagcc cttccagatt
    34441 aagcccgctg cgtcccagcg ctgaaataat cccggaggtg gcggtttgtc caaggccaaa
    34501 cggattacca accgccacgg cgaaatcgcc gacgcggagt ttgtcggaat cggcgatggc
    34561 aatttgcgtt aacttgctgg gattctgaat ttgtaacaga gcgatatcgc tctggtcgtc
    34621 gccgccgatc agcttcgcgt cgaattcgcg tccgtcattc agttgaatgc tgatcttctg
    34681 tgcctgatta atcacatgat tattggttaa tacatagcct ttcgcggcat cgataatcac
    34741 ccccgaaccg agtccttcaa acggctggga cggctggtct ggcagatcct cgccaaagaa
    34801 ttttttaaac tcctccggca ctttttggct ctgggtggcg gttccctcga cttttacgct
    34861 gacgacagca ggcagcactt tctccagcat aggggcaagg cttggcagcg tcgcctggcc
    34921 tggcacctgg cctggtatcg atgcaagggc tggaaacggt gccgaaagag ttaatccgac
    34981 acttaacgct aatgcactta acagctgggt gtgttttttc atggatgctg ctctcgtacc
    35041 ttgaatgaac ggatagacaa ttcaaaacag attgatgtta ttgaattttc agcctggtaa
    35101 caatgataat agctgggaca ggaaagatag agagagggcg caagcgatgc gcccgataaa
    35161 tttcttaacg gcgtgcgatt aatcgcgctt tgcgccgcta cgtaacaggc cagacgcgcc
    35221 ttcagaataa tcacgtggca tttgtactgg cgcctgatcg ttgctcgcct cagactccgc
    35281 cagacggtta cggaacggat tcgactccgc agacatttcc ggcagcaggc tgctggagct
    35341 tttcgccata tactgataca gctggcggta atcatgcgcc atggtatcca gcagttccgc
    35401 gctgcgggca aagtggctaa ccagctcttc acggtactct tccagctcag ctttgttttt
    35461 ttccagttcg tactgcaatg cctgctgttg acgtaactta cgattaccaa aacgcatggc
    35521 cacggcacca atgatgatac cgacgactaa tccaattagc gcatattccc aggtcatgaa
    35581 catctcccgt tgtcttatgt ttccgtaggg tgttggctcc aggctccatg cccgcgcctg
    35641 attatgccac tataaccgct aatttcgtag aagtggaatc ccgacagcat atcgcgtagt
    35701 gtagaacggc ctttttttcg tcagccgtga acgacggcac atcgattttc aaggaataac
    35761 aataacatta tgcaaagtct ttcccctaca tcgcgttatc tccaggcact caacgaaggc
    35821 acccatcagc ctgacgacgt acagaaagag gcggtcgacc gtctggaaac cctttatcag
    35881 gcgctcaccg cgaaaaaatc gtcggctacg ccacccggcg gtctgatagc gcgactgggg
    35941 aaattattag gcaaaaacga accggacgcg caaataccgg ttcgcgggct gtatatgtgg
    36001 gggggcgtgg gtcgcggcaa aacctggctc atggatctct tctaccacag cctgccgggt
    36061 gagcgaaaat tgcgcctgca ttttcatcgg tttatgctgc gcgtgcatga agagcttacc
    36121 gcgctacagg gacagatcga tccgttagac attattgccg atcggtttaa aaccgagacg
    36181 gacgtactgt gtttcgatga gtttttcgtc accgatatta ccgacgccat gctgctgggc
    36241 ggtttaatga aagcgctgtt tgcacgcggc attacgctgg tcgcgacctc caatattccg
    36301 ccggaggaac tctaccgcaa cggtttgcaa cgcgcccgct tcctgccggc tatcgatgcc
    36361 attaaacagc actgcgacat tatgaatgtg gacgccggcg tcgattaccg gctgcggacg
    36421 ctgacgcagg cccatttatg gctaacgccg cttaatgatg aaacccggcg gcaaatggat
    36481 aaactgtggc tggcgttagc gggggccgca cgagaacatg ctccgacgct ggaaatcaat
    36541 catcgccctt tatccaccct gggcgttgaa aaccaaacgt tagcggcctc tttcgctacg
    36601 ctgtgcgtcg aggctcgcag ccagcatgat tacattgcgc tctcaaggtt atttcacacg
    36661 gttctgttgt ttgacgtgcc ggtcatgacg ccgctgatgg agaacgaagc gcgccgcttt
    36721 attgcgctgg tggatgagtt ttacgagcgc cacgttaagc tggtggtcag cgccgccgcg
    36781 ccgttatatg agatttatca gggggagcga ctcaagtttg aatttcagcg ctgtctgtcg
    36841 cgcctgcaag agatgcagag tgcggagtat ctcaagcggg agcatatgcc gtaagccgga
    36901 caagcgtagc gctccggcat tatgcggtat tatatctgtg caacctcccc gaccgagggt
    36961 gaactaggcc tgaacaaaac ccgcggcaaa tcgcaaaaag gggtcgatct ttgacctgga
    37021 cttctctata atcctgcgac cccacgttac aagagagttt tttcccaaac tttctctgtg
    37081 ccggccaaac atatccgagg gggtaggttt accggacttt gtcgtgtgaa cctcaactat
    37141 ttaaacgttt gggtgttcac caacgtgtaa cttatttatt tgggtaagct tttaatgaaa
    37201 acttttacag ctaaaccaga aaccgtaaaa cgcgactggt atgttgttga cgcgaccggt
    37261 aaaactctgg gccgtctggc tactgaactg gctcgtcgcc tgcgcggtaa gcacaaagcg
    37321 gaatacactc cgcacgtaga taccggtgat tacatcatcg ttctgaacgc tgacaaagtt
    37381 gctgtaaccg gcaacaagcg tactgacaaa gtgtactatc accacaccgg ccacatcggt
    37441 ggtatcaaac aagcgacctt tgaagagatg attgcccgcc gtcctgagcg tgtgattgaa
    37501 atcgcggtta aaggcatgct gccaaaaggc ccgctgggtc gtgctatgtt ccgtaaactg
    37561 aaagtttacg cgggcaacga gcacaaccac gcggcacagc aaccgcaagt tcttgacatc
    37621 taatcgggat tataggcaat ggctgaaaat caatactacg gcactggtcg ccgcaaaagt
    37681 tccgcagctc gcgttttcat caagccgggc aacggtaaaa tcgttatcaa ccaacgttct
    37741 ctggaacagt acttcggtcg tgaaactgcc cgcatggtag ttcgtcagcc gctggaactg
    37801 gtcgacatgg ttgagaaact ggatctgtac atcactgtta aaggtggtgg tatctctggt
    37861 caggctggtg cgatccgtca cggtatcacc cgcgctctga tggagtacga cgagtccctg
    37921 cgtggcgaac tgcgtaaagc tggcttcgtt actcgtgacg ctcgtcaggt tgaacgtaag
    37981 aaagtcggcc tgcgtaaagc acgtcgtcgt ccgcagttct ccaaacgtta attgttttct
    38041 gcttcggcag acaactgtta gcgaaaaaac ccgctttggc gggttttttt atgggcaatg
    38101 catttatctg tcacaatgaa atgcggattg ttgtctcttt ttccccaatt ccagaatcga
    38161 ctcaccacaa aggtcacaaa atctggtaaa ctatcatcca attttctgcc caaatagcgg
    38221 ggaatgttca ttttttgtct cgtttctgag caatgatggc ttttttcgcc ctgggtgaca
    38281 taacatctgg ctggtcacat tgtggctggt agcagtaaaa attctgaata tacctggagg
    38341 ttttcatggc tgtcgctgcc aacaaacgtt cggtaatgac gctgttttct ggtcctactg
    38401 acatctatag ccatcaggtc cgcattgtgt tggctgaaaa gggtgttagt tttgagatcg
    38461 aacatgtgga aaaggacaat ccacctcagg atctgattga cctcaacccg aatcaaagcg
    38521 ttccgacact ggtggatcgt gagctgaccc tgtgggaatc tcgcatcatt atggaatatc
    38581 tggatgagcg tttcccccat ccgccgctga tgccggttta tccggtcgcg cgcggtgaaa
    38641 gccgtctgta catgcaccgt attgaaaaag actggtatac gctgatgaac gtcatcgtaa
    38701 acgggtctgc ttccgaggtc gactctgcgc gtaaacaact gcgtgaagag ctgctggcga
    38761 ttgcgccggt atttggtcag aaaccgtatt tcctgagcga cgaattcagc ctggttgatt
    38821 gctacctggc gcctctcctg tggcgtttac cgcagttggg tatcgaattc agcggcgcag
    38881 gggcgaaaga gctgaaaggc tatatgaccc gcgtctttga acgtgattct ttcctggctt
    38941 ctttaaccga agctgaacgt gaaatgcgcc tcggtcgggg ttaacctgta tggatttgtc
    39001 acagttgacg ccgcgtcgtc cctatctgtt gcgtgctttc tacgagtggt tgctggataa
    39061 ccagttgacc ccgcatctgg tggtggatgt gatgctgcct ggcgtgcatg tccctatgga
    39121 atatgcgcgc gatgggcaaa tcgtcctcaa tattgcgccg cgggcggtag gtaatctgga
    39181 gctgtctaat gatgaagtgc gttttaatgc gcgcttcggc ggcgttcccc gtcaggtttc
    39241 tgtgcctttg gctgcggtgc tggcgattta cgcccgtgaa aacggcgcag gcaccatgtt
    39301 tgagcctgaa gccgcctatg atgaagacgt tgtcagctta aatgatgatg acaataccgc
    39361 aggcgcggaa agcgagaccg tgatgtccgt cattgatggc gataagcccg accacgatga
    39421 cgacagtagt cctgatgacg agccgcctcc gccgcgtggc ggacgtccgg cgctgcgcgt
    39481 agtaaaataa tcaacaggcc ctgaagggcc tgttttgttt ggtctcctcg cgggttcacc
    39541 ctgcttttga agctgtgtta cgataagctt gctattattt gccaccgacc actcatgaat
    39601 ggacgttatg aacgcatttg attcgcaagc agaagattca ccgacatccc tcgggcgtag
    39661 tttgcgccgc cgcccgctgg cgcgtaaaaa actgtctgaa atggttgagg aagagctgga
    39721 gcagatgatc cgccgtcatg agtttggcga gggagaacag ctaccgtctg aacgtgaatt
    39781 aatggccttc ttcaatgtgg gacgtccctc cgtgcgtgaa gcgttagctg cgctgaagcg
    39841 taaaggtctg gtgcaaatca ataacggcga acgcgcccgc gtctcgcgcc cctctgctga
    39901 taccatcatc agcgaactgt cgggtatggc gaaagatttt cttactcatc ctggcggcat
    39961 cgctcacttt gaacagctac ggcttttctt tgaatccagc ctggtacgct atgcggcgga
    40021 acatgccacc gacgagcaga tcgcgttgtt aacgaaagcg ctggaaatta atagccagtc
    40081 gctggatgac aacgcgctgt ttattcgttc ggatgtcgag tttcaccggg tgctggctga
    40141 aattcccggc aatccgatct ttatggctat tcatgttgct ctgctggact ggctaatcgc
    40201 tgctcgccca agcgttcccg atcgtgagct gcatgaacat aataacgtga gttatcaaca
    40261 gcatattgtg attgttgatg ccattcgcca gcgagatccc gataaagcgg atcgcgctct
    40321 gcaaacccac ctcaatagcg tttccgctac ctggcacgcg ctcggtaaaa aaagtcaaaa
    40381 aatgcggtag cgatcgcacc tccgatcccg gtttagtgaa gcagatcgca ctataagcgt
    40441 tctgtattat ttgctgctta tttgatctgg tataacaggt ataaaggtag gtagttaata
    40501 tattcatcat ccgtagaggt aggtatggca aaagcattgc aaggcgtaat ggcggcgttg
    40561 ttgaccccat ttgatcatca gcagcaactg gatagcgaaa gcctgcgccg tctggtgcgt
    40621 tttaacatcg ggcagggtat cgacgggctg tacgttggcg gttccaccgg ggaagcattc
    40681 gtacagagcc ttgctgaaag agagcaggta ctggagattg tcgccgaaga ggcgaaggga
    40741 aaaatcacgt tgatcgccca tgtcgggaca gtaagcaccg cagaaagcca gcagcttgcc
    40801 agcgccgcaa agcgttacgg ttttgatgcg gtctctgcgg tgacgccttt ttattaccct
    40861 ttcagttttg aagagcactg tgaccattat cgggcaatca ttgattccgc agatggattg
    40921 ccgatggtgg tatacaacat tccggcgtta agcggcgtaa aacttaccct cgatcagatc
    40981 aatacgctgg tgacattacc gggcgtgaac gcgctgaagc aaacctccgg cgatctcttc
    41041 cagatggagc agatccgccg cgcgcatccg gatctggtgc tgtacaacgg ttatgacgaa
    41101 atcttcgctt ccggtctgct ggcgggcgcg gacggcggta tcggcagcac atacaacatt
    41161 atgggttggc gttatcaggg gattgttcag gcattgcgtg agggcgatgt ggcgaaagcg
    41221 cagcgtctgc aaaccgagtg caataaggtt attgatttac tgattaaaac cggcgtattc
    41281 cgcggcctga aaacggtcct gcattatatg gacgtggtat cggtgccgct atgtcgtaaa
    41341 ccgtttgcgc ctgttgatga aaaatatctg ccggcgctca aggcgctggc tcaacaactg
    41401 atggaagaaa aggcgtaaca gcataatgcc gggggcgcta cgcttgcccg gcctacaaca
    41461 gtgcgaacag taggccggat aaggcggagc cgccattcgg cataacgaca acaaaaatcg
    41521 tcgggagagt aaaatgagta cttctaccca gaacatcccg tggtatcgcc atctcaaccg
    41581 ggcgcaatgg cgggcatttt ccgctgcctg gttgggatat ctgcttgatg gttttgattt
    41641 tgtgttaatt gctcttgtac tgactgaggt acaaagcgaa tttgggctga cgacggtaca
    41701 ggcggcaagc ctgatttctg cggcttttat ctctcgctgg ttcggcgggt tattactggg
    41761 cgcgatgggc gatcgctatg ggcgtcgtct ggcgatggtc agcagcatca ttctgttttc
    41821 ggtgggaacc ctggcctgcg ggtttgcgcc cggttacacc accatgttca tcgcccgact
    41881 ggtgattggt atgggcatgg cgggcgaata tggttccagc gcgacctatg tgattgaaag
    41941 ctggccaaaa catttacgca ataaagccag tggttttctg atttccggct tctccgtcgg
    42001 cgcggtcgtt gccgcgcagg tgtacagcct ggtggtgcct gtctggggct ggcgcgcgct
    42061 gtttttcatt ggcattttgc caattatctt cgccctctgg ctgcggaaaa acattccgga
    42121 agcggaagac tggaaagaaa aacacgcggg taaagcgccg gtacgcacga tggtcgacat
    42181 tctttatcgg ggcgaacatc gtatcatcaa cattttaatg accttcgccg ccgccgctgc
    42241 gctgtggttc tgttttgccg gtaacctaca aaatgctgcg attgtggcgg ggctgggact
    42301 actgtgcgcg gttatcttta tcagctttat ggtgcagagc agcggtaaac gctggcccac
    42361 tggcgtcatg ctgatgctgg tggtactgtt tgctttcctc tattcttggc cgattcaggc
    42421 gctattacct acttatctga aaaccgagct ggcctacgat ccgcatacgg tggcgaatgt
    42481 cctgttcttt agcggatttg gcgcggcggt tggttgttgc gtaggcggtt ttcttggcga
    42541 ctggctggga acgcgtaaag catatgtctg tagcctgctg gcctcgcaaa tcctcattat
    42601 tccggtcttt gcgattggcg gcacaaacgt ctgggttctg ggtctgctac tgtttttcca
    42661 acagatgttg gggcagggga ttgccgggat tctgccgaaa ctgatcggcg gttacttcga
    42721 taccgatcag cgcgcggcgg ggctgggctt tacttataac gtcggcgcgc tcggcggcgc
    42781 gctggcaccg atcctgggag cgctgatcgc tcaacgtctg gatctgggca ctgcgctggc
    42841 atcgctctct ttcagcctga cgtttgtcgt gatcctgctt attgggcttg atatgccgtc
    42901 tcgcgtacag cgttggctac gtccggaagc gttacgcacc catgatgcta tcgacgacaa
    42961 accgttcagc ggagccgtac cgcttggcag tggtaaaggt gcctttgtaa aaacgaaaag
    43021 ttaatccgct tgcccggttt tcaaccgggc aatatttgta agggagtagt atgtcgttac
    43081 ttgaacaact ggataaaaat attgccgctt ctggcggcct gattgtctcc tgccagcccg
    43141 ttccgggcag tccgctggat aagccggaga ttgtagcggc aatggcgttg gcggcggaac
    43201 aggcgggcgc ggttgcggtg cgtattgaag gcatagacaa cctgcgcgtg gcccgttcgc
    43261 tcgtttcggt acccattatc ggcattatca aacgcgatct ggacgactct ccagtgcgca
    43321 ttaccccttt tctcgacgat gtagatgcgc tggcgcagct attatcgccg ttgatggaac
    43381 cgctcggcaa cggccggtag ccgttgaggc gttgttggcg cgcattcatc accaccatct
    43441 actggcgatg gccgactgct catccgtgga cgatggtctc gcctgccaac ggttgggcgc
    43501 ggacattatc ggcacgacaa tgtccggcta caccaccccc gatacgccgg aggaacccga
    43561 tctgccctta gtcaaagcgt tgcgtgacgc cggatgccgg gtaatagccg aagggcgcta
    43621 taactcgcca gcactggcgg cggaggcgat ccgctatggc gcatgggcgg tgacggtggg
    43681 gtccgccatt acccgtctgg aacatatctg tggatggtat aacgacgcat taaaaaaggc
    43741 ggcgtcatga ctacgttagc aatcgatatt ggcggtacta aacttgccgc cgcgctcatc
    43801 gacaacaact tgcgcattag ccagcgtcgc gagctaccga cccccgcgag caaaacgccg
    43861 gatgcgttac gtgaagcatt aaaggcgctg gttgaaccac tacgggcaga ggcgcgtcag
    43921 gtagcgatag cttctaccgg gatcattcag gaagggatgc tgctggcgct aaacccccat
    43981 aatctgggcg gcttgctaca ctttccgtta gtacaaacac tggaaacgat cgctggcctg
    44041 ccgacgctgg cggtgaacga cgcgcaggcg gcggcctggg cggagtatca cgcgctccct
    44101 gatgatatcc gcgatatggt atttatcacc gtttcaaccg gcgttggcgg cggcgttgtc
    44161 tgcgacggca agctccttac cggaaaaggc ggtctggccg ggcacctggg acacaccctg
    44221 gcggacccac acgggcccgt atgcggctgt ggacgcgttg gttgtgtaga ggccatcgcc
    44281 tccggacgag ggatggccgc ggcggcgcgg gacgatctgg cgggatgcga cgccaaaacc
    44341 ctatttattc gcgctggcga aggtcatcag caggcgcgac atctggtaag ccaatccgcg
    44401 caggtaatag cgcgaatgat cgccgatgtg aaagcgatta ccgactgcca gtgtgtggtc
    44461 attggcggca gcgtagggtt agctgaggga tacctggagc aggttcgcgc gtttttgatg
    44521 caagagcctg agccttatca cgtggcgctg agcgccgctc gctatcggca tgacgcagga
    44581 ttattaggcg ctgctttgtt agctcaagga gacacattat gatgatgggg gaagtacagt
    44641 cgttgccttc ttgcgggttg catccgcgac tgctggatgc cttgactctc gcgctggcgg
    44701 caaggccgca ggagaaagca ccggggcgct atgaattgca gggcgacaat atctttatga
    44761 atgtaatgca gttaacgacg caaatgcctg ccgggaagaa agcggaattg catgaacaat
    44821 acattgatat tcagctacta ctaaccggcg tcgagcgtat tgcgtttggg atgtccggtg
    44881 ccgctcgcca gtgcgaggag atgcacgttg aagaggatta ccagctttgt agtcaaattg
    44941 ccgacgagca gactattacg ctgcaagcgg ggatgtttgc tgtgtttatg ccgggagaac
    45001 cgcataaacc gggatgtgca gtgggtgaac cggatgacat caagaaagtg gtagtgaaag
    45061 tacgcgccag tttgctggcg gcctgaatct cttgccggag cagtcttccg aacgcagccc
    45121 cttacgggct gcgtggtgaa tgtgccggag agcgcgggta tgacgggtta acgcttaaac
    45181 gtcacggctt ccggctgggt caggtgcagc gtcgtctggc tcggcaccgt ctcggcaatc
    45241 acccgcctgt ggcgaattga gtaacgggca ggcgtctggc gacgtaccgc atcgaatcca
    45301 ttctcagcgg gtaagataac cagattcgcg gcattgccga cgctcagacc gtagtcctgc
    45361 aggtgcaaag tttttgcgct gtgggtagtg atcagattta acccgtcgtt gatttgccca
    45421 taccccatca actggcaaac gtgtaacccc atatgcagca cctgcagcat attggcggtg
    45481 cctaatggat accacgggtc gaagacgtca tcatggccaa agcagacgtt gatccccgct
    45541 tccagcatct ctttcactcg cgtgacgcca cgacgtttcg ggtaagtgtc aaaccgccct
    45601 tgcagatgaa tatttaccag cgggttggcg acgaagttaa tccccgacat tttcaacaga
    45661 cggaacaggc gtgacgcata cgcgccgttg tacgagtgca tagccgtggt gtggctggcg
    45721 gtcacgcgcg cccccatgcc atcacgatgc gccagcgccg cgaccgtttc gacaaagcga
    45781 gactgctcgt catcaatttc gtcgcagtgc acatcgatca agcgatcgta tttttgcgcc
    45841 agggcgaagg ttttgtgcag cgattcaacg ccatattccc gcgtgaactc aaagtgcgga
    45901 atggcgccaa taacgtcagc gcccaaacgc acggcttcct ctaacagcgc ttcaccgttg
    45961 ggataagaca gaataccttc ttgcggaaag gcgacgattt gtaggtctac ccacggcgca
    46021 acctcttgct tcacttccag catggctttc agcgcggtga gcgtaggatc tgaaacgtca
    46081 acgtgagtac gaacgtactg gatgccgtta gccatctgcc atttcagggt ctgcatcgcg
    46141 cgcgctttca catcttcatg cgtgagcatt gctttacgtt ctgcccagcg ctcaatccct
    46201 tcaaacagtg tgccggactg gttccagctc ggttcacccg ccgtttgcgt ggtatccagg
    46261 tggatatgtg gctcaacaaa cggtggaata gccagaccgc cttcggcatc aagcacttcg
    46321 ccctgcggta acgatgtggc ttcctgaggc tcaatccggc taaagcgccc gttttcaatc
    46381 gtaatctgcc ataatccttc gtgtccctgc agacgcgtct gacgaatagt gatgttattg
    46441 ttctgcatgg ctgacctctg gtgatttagc aaggctgcgg ttgaaaagtg gattcagcag
    46501 gatatagctg aagacgccgc cgagtacggc gttgacgggc acaataccag gaacataatg
    46561 tccggcggcg atgcccagcg cgacggaaag aatagcaatc cagttaacgg gaataaagcg
    46621 cacggtgttg aagtcggcat agcggcggcg gttcaccaga tagtcggcaa taatcactcc
    46681 accaatcggt gggatggcag atgacaggaa cgtcagccag ccgacaaaat tattgtaaag
    46741 ccacagcgcg cacacggtac cgataatccc gttcaccacc gacagcgtgc ggctggaaag
    46801 accggtaata ttggcgaagc ccagacccga tgcgtacagc gcgttatcgt tggtggtcca
    46861 gatattcagg ccaagcacca caatcgcggg cagcagcagc ccctgcgcta tcatcacgtc
    46921 agagatatcc gcctgaccga cggcggcagc gcctgccgcg ccgaagataa acatcagcga
    46981 gttaccgagg aaaaaagcga ccatcgcaat cagtacggcg cttttggcat gacgtccgaa
    47041 gcggacgaag tcggcggtca atgtaccggc gctgacaaac gagcccacca ccagcgccag
    47101 cgcgctggaa aaatccagcg gcgtctgcgg cactatcgtt tttaaatgct ccagcccacc
    47161 cacgccgctg accgccagcc agacggagta gctgcccaga ataacgatcg cgggtacggc
    47221 aacgatagac aaaatggtca acgccgagat gccgaaaaaa atggtcaggg tcatcagcag
    47281 acccgaaacg gcaatcagga tattggcatc aatgcccgtc gctttactga ccggaatagc
    47341 gaacatcgct acgccaacgc caaaccagcc cacttgagta ctgcctaaca gcagcgaggg
    47401 aagccatgag cctttaacgc caaaggagta acgtgcaagg aggtgggtgg agagtccggt
    47461 ttttgcgccg atgtagccaa gaaatgcagt gtagataccg aggaggagat taccgaagaa
    47521 aactgcgagg aagaaatcat gataggtaag accggtgccg agtgtccctc cggtccacat
    47581 actggcggaa aaaaacgtta aacccaacat gacaaacgtc agtggaatca cgcccttccg
    47641 cgccgcctgg ggaactggcc cctggctata attgttgtcc tgcgacacaa cgcctccatg
    47701 aattttgccc aaaaaatccg ccgcataata tacagttctc agaataaagc aaacgttttc
    47761 gtgtgatatt ttttttgata attattcatg gcattaatgg ttcgctagtt tttctccgtt
    47821 gtcagtgaac caccgcgtgt gagttgagtt tccagcatgg tttgcgaacg aataagttcg
    47881 tctgtgagta atttttcgtc gggcaactgc actttgtact cgctcgccat gatggtgttt
    47941 ggcaggccag tcagcgcgta atgcgcttcc cccgcgcctt tccctgcgca caaaaccagg
    48001 ccgactggcg ggttttctcc gggcattgtc cagtgctctt tggcatagtt caggtacata
    48061 ttcatctgcc cggcatccgc ataaccgaat ttgcctacct tcaggtcaac gagcaacagg
    48121 cagcgcaagc gacgatggaa gaacagcaga tcgacgcgga accagctatt gtctatgcgt
    48181 agtcggcgtt ggcggccaac aaaagcaaaa tcgtcaccga gctccagcat aaagtccatc
    48241 aggtggctga gcagcgcgtc ttcgagatct gattcggaat actcgtcctt caggttaaga
    48301 aattccagaa tgaacgggtc gcgtatggct tgctccggca aaacgtttgg ctcggcgggt
    48361 gcaggctgct gcaacatggc ggatttgtcg tgggacagta gcgttcgttc gtaaaattga
    48421 gtggcgattt gccgatcgag ttgccgtacg gaccagccgt tacgtagcgt ctctttctcg
    48481 taaaaagtgc gggcatcgtt atctttcacc gacagcagac gcacataagc tgaccaggga
    48541 agagggaatg ttttggcgag cggtatgaga tttgaagatt ccgcagacag tgtctgcgga
    48601 atttcaatgt gttgaaaaca aagataaaat gtacgaattt gccataggtt tctgttggaa
    48661 aaaccgcgct tatagcgctg acttaaatct accgataatc gttcgataag ctgggtgcca
    48721 taggccgctc gcgcttctcc tccctgttca aattcgacaa tacgtcggcc aatttcccag
    48781 taggtggcag tcataatggc attgatgctg cgcacggtct cggtacgtgc cgtatcgacc
    48841 agacgaataa taccgtcatg aatttgctga tattcatcag actgtggcgc taaagttgga
    48901 ttcgtcatgt catcccttac gtgatagttt cattgtgaaa ttagaacgct atcaatacgc
    48961 ttcaggcgta aacgaatcaa tccatgaacg gattttacat ggcattacat ctcgatttac
    49021 gagcgggttt ccagaatcgg caggagagat attgaggaga ggaatatcgg ctccccagcc
    49081 atcagcacaa ggcatcaacc ggggagccga aagggttaca cttcgaggta gttcataatc
    49141 ccgtcagccg ctttacggcc ttcggcaatc gccgtcacca ccagatcgga accgcgcacg
    49201 atgtcgccac cggcgaagat tttcgggttg ctggtctgga aagcattatc gctgcgttcc
    49261 ggcgcgataa ttcgtccctg cgagtccagt tccacgctgt gtttcgccag ccattccatg
    49321 ctgtgtggac gaaaaccaaa cgccatcacc accgcatcag ccggaaccac atgctcggaa
    49381 ccggcgacga tctccgcccg ccgacggcct ttggcatccg gttcgcccat ttcagtgcgc
    49441 accattttta cgccgctcac tttgccgttg gcattgactt caatgcccag cggttgaacg
    49501 ttaaactgaa actcgacacc ttcctcgcgc gcgtttttca cttcgcgtct ggaacccggc
    49561 atgttctctt catcacgacg ataagcacag gttacgtgcg ttgcgccctg gcgtatggaa
    49621 gtgcgtacgc agtccattgc ggtatcgccg ccgcccagca ccaccacgcg tttgccttcc
    49681 atgctgacat atggttcgtc gctggtttcg ccaaacccca tgatctgctt cgtattggcg
    49741 atcaggaacg gtagagcgtc gaaaaccccg tccgcatctt cattttccag cccgccgcgc
    49801 atcgactgat aggtgccgac gccaaggaat accgcatcgt aatctttcag cagatcttca
    49861 agctgtacat cacgacccac ttcggtatta agtttgaact caatacccat gccggtgaag
    49921 atctcgcgac gacgggtcat cacctctttt tccagtttga aagctggaat accgaaggtc
    49981 agcagaccac cgatttccgg atggcgatca aagaccaccg ccttcacgcc gttgcgggtc
    50041 agcacgtcgg cgcacgccag ccctgccgga ccagcgccga taatcgctac ccgtttgtcc
    50101 gtctggcgca cgccggtcat atccgggcgc cagcccattt cgaacgcttt atcgttgata
    50161 tagcgctcaa tgttaccgat ggtcactgcg ccgaactcat cgtgcagcgt acaggagcct
    50221 tcgcacaggc ggtcctgcgg gcagacgcgg ccacacactt ccggcagggt gttggtctgg
    50281 tgcgatagct cagccgcctc aaaaatacgc ccttcgttag ccagtttcag ccagttcggg
    50341 atgtagttat gtaccggaca tttccactcg cagtaggggt tcccgcagga caaacagcga
    50401 tccgcctggg ctttcgcctg accttcagaa aacggttcgt agatttcaac aaactcgatc
    50461 ttacggagct tcagcggttt cttcggcgga tcaacgcgct gcaggtcgat aaattgataa
    50521 acattctggc tcatttcaat tccttactgc gcctgcacgc gcaattctgc cgcactacga
    50581 ctacggtggc ccaacagggc tttgacatcg ctggacttgg gcttaactaa cgcgaattgg
    50641 gttgagaagc ttgaccacct ggacaggatc tcttcgccgc gttgcgaacc agtatgttgc
    50701 acgtgctcgg tgatcaggcc gcgcagatgc tcttcgtgga tagccagcga atcaacgtcc
    50761 agtacttcta ccagttccgg gttcacgcgt ttacggaatt cgccatcttc gtccagcaca
    50821 taggcgaagc cgccggtcat ccccgcgccg aagttaacgc cggttttacc cagcacgcag
    50881 acgatgccgc cggtcatgta ttcacagccg ttgtcgccga tgccctctac tacggtaatc
    50941 gccccggagt tacgcacgcc gaaacgttcg cccgcgcgcc ccgccgcgta cagacggcca
    51001 ccggtcgctc catacaggca ggtgttgccg atgatgctgg ctttatggct gaggaaggcg
    51061 gaacctaccg gtggtctgat ggcgatcaaa ccgcctgcca tacctttacc gacatagtcg
    51121 ttggcatcgc cagtcagata taactccacg ccgcccgcgt tccacacgcc aaagctctgg
    51181 cctgcggtac cgctgaagtg cgctttaatc ggatcggaag ccagcccctg atcgccgtgg
    51241 gtctgtgcga tgtaaccgga aagcgacgca cccacggaac gatcggtgtt gcggatgtcg
    51301 aaccagaagg ttttgctctg gcgcgcatcg acaaacggct tcgcctgctg caacagttgc
    51361 gcattcagca caccgttatc aaacggcggg ttattctcgg tgcagtacag cgctttaccc
    51421 ggatgaggtt cagcggtttc cagtagacga gacagcgcca gcttctgctg tttagcggtg
    51481 aagccctcca gctctttcag caggtcggtg cggccaatca aatccaccag gcgggtcacg
    51541 ccaagcgaag ccatcagctc gcgcacttcg cgggcgataa attcaaagta gttggtcact
    51601 ttgaacggca ggccgtgata gtggttctta cgcagttttt catcctgcgt cgccacgccg
    51661 gttgcgcagt tgttcagatg gcaaatgcgc aggtatttac agcccagcgc caccatcggg
    51721 ccggtgccga agccgaaact ttctgcaccg agaatcgccg ctttgatgat atcgacgccg
    51781 gttttcagac cgccgtccac ctgcagacga atcttgtgac gcagaccgtt ggcgaccagc
    51841 gcctgctggg tttcaacaag tcctagttcc cacgggcagc cagcgtattt caccgaagag
    51901 agcgggcttg cgccggtacc gccgtcgtag ccagcgatgg tgatgaggtc tgcataggct
    51961 ttcgccacgc cggtcgcgat ggtgccgacg cccggttcgg acaccagctt cacggagatc
    52021 atcgccttcg ggttgacctg tttgaggtcg aaaatgagct gcgctaagtc ctcgatagag
    52081 taaatatcgt ggtgcggcgg cggggagatc agcgtcacgc ccggcactga atagcgcagt
    52141 ttagcgatat acggagtgac tttatccccc ggcaactgac cgccttcgcc cggtttcgcg
    52201 ccctgcgcga ctttaatctg aatcacatcg gcattgacca ggtacgctgg cgtcacgcca
    52261 aaacggccgg aagccacctg cttgatacgc gacactttat tggtgccgta gcgcgccggg
    52321 tcttcgccgc cttcgccgga gttggagttg ccgccgaggc tgttcatcgc ttccgccagc
    52381 gcttcgtgcg cttccggact taatgcgccg atagacatgg ctgcggtatc aaagcgttta
    52441 aacagctcac tggcgggctc aacctcgtcg atagtcaccg cctcgccgtc tggatgtatc
    52501 gccagcagat cgcgcagcgt tgcagccgga cgctcattga ccagtttggc gtattcctga
    52561 taatcgctgt actcgccgct ctgtaccgcc tgttgcaggg tacgcacgac atccgggtta
    52621 taggcgtgat attcgccgcc gtggacgtac ttcagcaggc cgcccgggct aatgggtttg
    52681 cgcgccagcc aggcgcgttt ggagagattc agcagatcct gctggaagtc atcaaagctc
    52741 gcgccgccga tacggctgac cacgccctgg aagcacaggt ttaccacatc atcgtgcagc
    52801 ccgaccgctt caaacagttt ggagcagcgg taagaggcaa tggtcgaaat gcccattttg
    52861 gacataatct tgtacagccc cttgttgatg ccgttacggt agttctgcat cacggtacgg
    52921 tagtttttag cgatggcctg ggtatcaatc agacgcccca gcgtttcgta ggccaggtac
    52981 ggatagatgg ccgttgcgcc aaagccgagc agtaccgcaa agtgatgcgg atcgcgggcg
    53041 cttccggttt ctacgatgat gttggcgtcg cagcgcaggc tttgatcgac cagacgagtc
    53101 tgcaccgcgc ccaccgccat cggcgcgggg accggcaggc gattcttacc gatattgcga
    53161 tccgagagga ccagcagcac ggtgccgttg cgcaccatct gttccgcttt atcgcacagc
    53221 gccttaaccg tcgcgtccag tgtggtttcg gtgacatcaa aggtaatgtc aagccagtcg
    53281 gcgcggtagt gatgctcgct catggtggtg agctgtttga aatcggagta cagcagaatt
    53341 ggcgatttaa aactcaggcg atgggcctga ccttccgctt cgcagaagac gttcatttcg
    53401 cgaccgatgc tggtggcgag cgacatgacg tgcgcttccc gcagcgggtc gataggcggg
    53461 ttagtaacct gcgcgaactg ctggcggaag tagtcgtaaa taatacgcgg ctggctggag
    53521 agcacggcaa agggggtatc gtcgcccatt gaaccgacgg cttcctggcc gttttcgccc
    53581 aacacgcgga taacggagtc cagctcttcg gcgctgtagt taaactgttt ctgatagctg
    53641 gcgagcaggt catcgtccag ttcgcggcta ccgacttctt catctggcaa ctcttcaaac
    53701 ggcaccagac ggcgaacatt cttttccatc cacgctttat acggatggcg gcttttcaga
    53761 tcgtcatcgg tttccgcgga atgcagaata cgtccgccgc gggtgtcgat caccatcagc
    53821 tcgcctgggc cgacgcggcc tttctcgacc acttcatccg gctgatagtc ccagataccg
    53881 acttcggagg cgcaggtgat cagcttatct ttggtaatga catagcgtgc cgggcgcagg
    53941 ccgttacggt caaggttaca ggcggcgaag cgcccgtcgg acatcacgat gcctgccgga
    54001 ccgtcccacg gctccatatg catggagtta aagtcaaaga aggcgcgcag atcctggtcc
    54061 atatcggggt tgttctgcca ggcgggcggc accaacaggc gcatggcgcg gataatgtcc
    54121 atcccgcctg ccagcagcag ttccagcatg ttgtccagcg agctggaatc cgaaccggtt
    54181 tcgttaacaa acggcgcagc ggattgtaaa tccgggatca gcggcgtctg gaatttatag
    54241 gtacgggcgc gcgcccactg gcggttgccg gtgatggtgt taatctcgcc gttatgcgcc
    54301 aggtagcgga acggctgcgc cagcggccaa cgcggcacgg tgttagtgga aaagcgctgg
    54361 tggaacaggc agatggccga ttccagacgc agatccgcaa gatccaggta gaagcgcggc
    54421 agatccgccg gcatacacag acctttataa atgttgacca ggttcgacag gctgcatacg
    54481 tagaaatctt tgtcgtcctg cagacgtttt tcaatgcgtc ggcgggcgat aaacagacgg
    54541 cgctccatat cgcgcggacg ccagcccgcc ggagcgttga caaaaatctg ctcaatacgc
    54601 ggcagggagg agagggcgat ttcaccgagc acgccttcat tggttggcac atcgcgccag
    54661 ccgacaatcg acagggtttc ctgctgtaat tcttcttcga caatatggcg tgacgcggcg
    54721 gccagttcag gatctttatt caaaaagatc atcccgacgg cgtagttttt ggctaagcgc
    54781 cagccgcgct cttcggccac gatgcgaaag aaacggtcag gtttttgtaa cagcaagccg
    54841 caaccgtcgc cggttttacc gtcggcaagg atcgcgccac ggtgctgcat ccgggccagc
    54901 gcgtgtatgg cggtacgcac taccttgtgg ctaggttcgc cttctatgtg ggcgatcagg
    54961 ccgaaaccac agttatcctt ctcaagggat ttatcgtaca acatatcagt gaacctcccc
    55021 aggctctacg ggacgctctc ccaaccgacg gcgcgcgggc acagcaagag catggcgacg
    55081 gggctggcgc atcatacgct tacctcgcat tcgccctctt tgtgtccttt gcgcattggt
    55141 aaatacggtt aagagggaat ctcaattact gcataaatat gatgagcaga cggctcatcc
    55201 agaaagcttc cagcggatcc ccaacttatc gggaatccac acccaggtca aatggcaaac
    55261 tgatttatgc aaaagtgtgc tgtagcacag ataacttttt taatctattg aaattaaaag
    55321 gttttttata gagtggttgc taatacggag cggcagaaag cctgtgatct gtctcactat
    55381 aagagccgct cgccaggagt tatctgacct tgctttttca aaaatcttgg cattttatgc
    55441 tgttttaagc gtgaacagca ttgaatgcta ctgtttttat cgatgaccca gcagacgctg
    55501 aaaaaagagg ggaatatcag gaaaaatcat cagcgggatt atgaatgaaa tatcgtttat
    55561 tttgcttgat tatgcaatgg ataaaagcct tccgggacga ttgatccagg tcatcgccaa
    55621 aggagactaa aaatggcagg ctttggcctc tttttaagag gcggtctatc agattatgca
    55681 gttacagaaa ttagtcaata tgtttggtgg ggatctttta cgtcggtatg ggcaaaaggt
    55741 tcataagctg acgcttcatg gcggttttag ctgccctaat cgcgacggca ccatcgggcg
    55801 tggcggttgc accttctgta atgtcgcctc ttttgccgat gaggcgcagc agcatcattc
    55861 gattgccgag cagcttgcgc atcaggcgca tctggtgaac cgcgctaaac gctatctggc
    55921 ctatttccag gcctacacca gcacctttgc agaagtgcag gtgctgcgtt ccatgtatca
    55981 acaggcggtc agccaggcca gtatcgtcgg gttatgcgtc ggtacgcgtc cggattgcgt
    56041 cccgcaggca gtagtagatt tactgtgtga atataaagat caaggctacg aggtgtggct
    56101 ggaactggga ttgcaaaccg cgcacgataa aaccctgcgc cgaattaacc gcgggcatga
    56161 cttcgcctgc tatcagcgta ccacccggat tgcccgggag cgcgggctga aagtgtgcgc
    56221 gcatctgatt gtggggctgc cgggagaagg gcaggcagaa tgcctgcaaa ccatggagcg
    56281 tgtggtggag acgggcgttg acggtattaa actgcatccg ctgcatattg tgaaaggcag
    56341 tacgatggcc aaagcctggg aagcggggcg gctgaacggc atcgaactgg acgactacac
    56401 gctaacggca ggtgagatga ttcgtcatac gccgccggag gtaatttatc accgaatttc
    56461 agccagcgct cgccgtccga cgctgcttgc cccgctgtgg tgcgagaatc gctggacggg
    56521 gatggttgag ctggacaaat acctgaatga gcatggcgtg cagggctctg cgctggcccg
    56581 tccctggata ccacctgtag cgtagcgtga tgagggggct acgcatattt cgcacaatat
    56641 tcaacgcggt tcccataatt gggtattatg tgcgaagttg tggtgaagga atcctctatg
    56701 aagcaaattc gtatgctggc gcaatactat gtcgacctga tgatgaaatt gggtctggtg
    56761 cgcttttcca tgctcctggc gttggcattg gtggtgctgg cgattgtcgt gcagatggcg
    56821 gtgaccatgg tgctgcatgg tcaggttgaa agtatcgacg ttattcgttc catctttttt
    56881 ggcctgttaa ttacgccctg ggcggtctat ttcttatccg ttgttgttga acaactggaa
    56941 gagtcaaggc agcgactgtc gcgtctggtg caaaagctgg aggagatgcg cgagcgcgat
    57001 ctcaagctta acgtacagtt gaaggacaat attgcccagc ttaatcagga aattgccgat
    57061 cgcgaaaaag cggaagcgga gctgcaagag acatttgaac agctaaaagt agaaattaaa
    57121 gagcgtgaag aggcgcaaat ccagctagaa cagcaatcct cttttctgcg ctcctttctg
    57181 gacgcctcgc cggatttggt tttttatcgt aatgaggata aagagttttc cggctgtaac
    57241 cgcgcaatgg aattgctaac cggcaagagc gaaaaacagc tggtgcattt gaagccggaa
    57301 gatgtgtact ctcccgaagc ggcggagaaa gtcattgaaa ccgatgaaaa agtattccgc
    57361 cataacgtct ccctgaccta cgaacagtgg ctggattatc cggacggacg aaaggcctgc
    57421 tttgaaattc gtaaagtgcc ttattacgac cgtgtcggta aacgtcatgg cctgatggga
    57481 tttggtcgtg atattaccga acgtaagcgt tatcaggacg cgctggagcg cgccagtcgc
    57541 gacaagacca catttatctc taccatcagt catgagctgc gcaccccgct taacggtatc
    57601 gtcggtttaa gccgcatcct gctggatacc gatcttaccg ccgaacagga aaaatacctt
    57661 aagacaatcc atgtctccgc cgtgacgtta ggcaatattt tcaatgatat cattgatatg
    57721 gataagatgg agcggcgtaa ggttcagctt gataaccaac cggttgattt caccagcttt
    57781 atggccgatc tggaaaacct ttccggtttg caggcgcagc aaaaagggct acgttttgtg
    57841 cttgagccga cgctgccgct gccgcacaaa gtcattaccg acggaacgcg tctgcgccag
    57901 attttatgga atttgatcag caatgcggtg aagtttactc agcagggcca ggtgacggtg
    57961 cgggcgcgct atgatgaagg cgacatgctg cactttgaag tggaagattc cgggatcggc
    58021 attccgcagg atgagcagga taaaattttc gccatgtatt atcaggtaaa agacagtcat
    58081 ggcggtaagc cggcgacggg gaccggtatc gggctggcgg tctcccgtcg gctggcgaaa
    58141 aatatgggcg gcgatattac cgtttccagt ctgccgggca aaggatcgac ctttacgcta
    58201 acggttcatg cgccagcggt ggcggaagag gtggaggacg cctttgatga agacgacatg
    58261 ccgctgcccg cgctgcatgt tctgctggtc gaagatattg aactgaacgt gattgtggcg
    58321 cgttcagtac tggaaaaact ggggaacagc gtggatgtcg cgatgaccgg caaggcggcg
    58381 ctggagatgt tcgcgccagg cgaatatgac ctggtcttac tggatattca gctaccggat
    58441 atgacgggtc tggatattgc cagagaactg acccgtcgcc acacgcggga agatttaccg
    58501 ccgctggtag cgcttacggc taacgttctg aaagataaaa aagagtatct ggacgctggt
    58561 atggacgatg tgctgagtaa gccgctgtcg gtgccagcct taaccgcgat gattaaaaaa
    58621 ttctgggatg ccaccgataa agaggagagt accgtgacgc ctgaagagag cgataaagcg
    58681 caagcgctgc tggatatccc gatgctggaa caatacatcg agttggttgg gcctaaattg
    58741 atcaccgacg gcctcgcggt gtttgaaaaa atgatgcttg gctatttaag cgtgctggag
    58801 tccaatctga cggcgcgtga caaaaaaggc gtcgttgagg aagggcataa gattaaaggc
    58861 gccgccggtt cggtagggct gcgtcatctg caacaacttg gccagcaaat ccagtcgccg
    58921 gatcttcccg cctgggaaga taatgtcgtg gaatggattg aagagatgaa gcaggagtgg
    58981 cagcacgatg tcgcggtgct gaaagcctgg gtggcaaacg cggaaaaaaa atgaccccgg
    59041 tttgaccggg gtgcgcgaat actgcgccaa caccagggaa atcgtggctg cgccgtgctt
    59101 attatgatga tgtcaaaggc gcagtcctgt tttcaggccg cacgcagtta agatagcaaa
    59161 tcctaaatga tttgttacat gaatcattta aatgtgtgaa gcgtagcatt ttaatcaaaa
    59221 ttattaatgg gcttgagtcg gttgcaggag gatgttcacc atgaaaaaaa ttggcgtagt
    59281 gctcagcgga tgcggcgtct atgacggcac cgaaattcat gaggccgttc tgacgctgtt
    59341 ggccattgcc cgcagcggcg cgcaggctat ctgcttcgcg ccggataaac cacaagcgga
    59401 tgttattaat cacctgaccg gcgaagctat ggcggaaacg cgtaacgtcc tgattgaggc
    59461 ggcgcgtatt acgcggggcg atattcgtcc tctgtcccag gctcagccag aggaactgga
    59521 tgcgctcatt gtgcctggtg gtttcggcgc ggcgaagaac ctgagtaatt tcgccagcaa
    59581 ggggagcgaa tgccgggtgg atagcgatgt cgtcgcgctg gcgaaggcca tgcaccagtc
    59641 cggcaagccg ctgggattca tctgtatcgc gcccgcaatg ttgccgaaaa tctttgactt
    59701 cccgctacgt ctgacaatag ggacggatat tgataccgct gaagtacttg aagagatggg
    59761 ggccgaacac gtaccttgcc cggttgatga tatcgttgtg gacgaggata acaaggtcgt
    59821 gaccacccct gcctatatgc tggcgcagga tatcgcccag gcggcaagcg gcattgataa
    59881 attagtgtcg cgcgtgctgg ttctggcgga atgagcaaac gacgcatcgc gccgttaacg
    59941 tttttgcgcc gtctactttt acgtatcctt gctgcgctcg ccgtcttttg gggcggcggc
    60001 attgcgctgt ttagcgtggt tccggtgcct ttttcggcgg tgatggcgga acggcagatt
    60061 agcgcctggc tcggcggaga gttcggttat gtggcgcatt ctgactgggt cagtatggcg
    60121 gatatctcgc cgtggatggg gctggcggta attgcggcgg aagaccagaa gttccctgag
    60181 cactggggct ttgatgttcc ggcgattgaa aaagcgctgg cgcataatga gcggaatgag
    60241 agccgtattc gcggcgcctc tacgctttcg cagcaaacgg cgaaaaatct ctttttatgg
    60301 gatggacgca gttgggtgcg caaaggtctg gaggccgggc taacgctggg cattgaaact
    60361 gtctggagca aaaagcgcat cctcacggtt tatctgaata tcgcggagtt tggcgatggt
    60421 atttttggcg tggaggctgc ggcacaacgg tattttcata aacctgccag tcgcttgagt
    60481 gtgtctgaag ccgcgttgct ggcggcggta ttgccaaatc cgttacgcta taaggcgaat
    60541 gcgccttctg gctatgtgcg tagccggcag gcgtggatta tgcgccagat gcgccaactg
    60601 ggcggggaat cttttatgac gcgcaaccag cttaattaat tttgccgatt ggcggcgcga
    60661 acgccttatc cggcctgcga tctgtgtcgt ccaggcctga taagcacagg ccattaagct
    60721 tcgtgagaag taagcgccag ccgtttcttg tcttttggct gcgcgtccct ctccagggca
    60781 acggccagcg caggctgggc gataaaccgc tgccacactc tctccagttt gcgttcacag
    60841 caccatgttg accaggtcgc cagcgggata aaggtacttt cccccagatt gtcgcaaacc
    60901 accggaacca cttctgactc gctgatacgc tggcacagga tattttgcgg cttcagcgac
    60961 atcgtcacaa tatggttatc cagcaggtaa cgtttcagtt ttttcagtag ccgccgcagg
    61021 acagcgacat cctcttcata acgacattgc gcggcgaact cggtcagggt aatagagggc
    61081 gcgccgttga aatcggtaat catgtcgtag acatagccgg tgccgcaatc ggtttctacc
    61141 gtgccgtaat aacgggggat agcgctccag tccgtcaggt agcgggacag atgcgcatag
    61201 tagctcagtt cacgccgaat ctctttatca ccgccgtggt cacggttgta aataactttt
    61261 atgcaacgcc gggcattatc cggatgcgta tagcatttac gatgtcgacc agcgcccagc
    61321 ggagtctgtt tggataaaag gatcatggca agtcctggaa aaatttattc acataaattt
    61381 agtatggaca aagaacttaa ataaaaccta aacgaaattt tttaaggttt tcttaatgtt
    61441 tttatgcata attaaagcgc acgaaa
//
LOCUS       DAJVKX010000007        60093 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000007 DAJVKX010000000
VERSION     DAJVKX010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 60093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60093
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.007"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(92..733)
                     /gene="lipB"
                     /locus_tag="OPY25_000415"
     CDS             complement(92..733)
                     /gene="lipB"
                     /locus_tag="OPY25_000415"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HCS0926131.1"
                     /translation="MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLV
                     TLLEQTVVNTLAEMGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAT"
     gene            complement(833..1096)
                     /locus_tag="OPY25_000416"
     CDS             complement(833..1096)
                     /locus_tag="OPY25_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HCS0926132.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYS
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGNIDIVRMVL"
     gene            complement(1204..2415)
                     /gene="dacA"
                     /locus_tag="OPY25_000417"
     CDS             complement(1204..2415)
                     /gene="dacA"
                     /locus_tag="OPY25_000417"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HCS0926133.1"
                     /translation="MKTTFSARFMQRMALTTALCATFISTAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADERRDPASLTKMMTSYVIGQAMKAGKFKETDLVTVGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYAVYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTSKAGYNLVASATEGQMRLISAVMGGRTYKG
                     RETESKKLLTWGFRFFETVNPLKAGKEFASEPAWFGNTDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNTAELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            complement(2554..3687)
                     /gene="rlpA"
                     /locus_tag="OPY25_000418"
     CDS             complement(2554..3687)
                     /gene="rlpA"
                     /locus_tag="OPY25_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HCS0926134.1"
                     /translation="MHKQLPVICVAAGIVLLAACTNDGGQQQTTVAPQPAVCNGPTVE
                     ISGAEPRYEPLNPTANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEM
                     FDPMQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGLYGTDRVISLSRAAADRLNT
                     SNNTKVRIDPIIVAPDGSLSGPGMACTTVAKQTYALPPRPDLSGGMGSASSAPAQPQG
                     DVLPVSNSTLKSDDTTGAPVSSSGFLGAPTTLAPGVLEGNEPTPAPQTAPVSAPVTAP
                     ATATPVSAPAAAAPVSAPVSAPAAAASGRFVVQVGAVSDQTRAQQYQQRLSQQFSVPG
                     RVIQNGAVWRIQLGPFASKAEASALQQRLQTEAQLQSFIASAQ"
     gene            complement(3698..4810)
                     /gene="mrdB"
                     /locus_tag="OPY25_000419"
                     /gene_synonym="rodA"
     CDS             complement(3698..4810)
                     /gene="mrdB"
                     /locus_tag="OPY25_000419"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HCS0926135.1"
                     /translation="MTDNPNKKTFWDKIHIDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVVMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAIVLIAAFIPILWFFLMHDYQRQRVMMLLDPE
                     TDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            complement(4813..6714)
                     /gene="mrdA"
                     /locus_tag="OPY25_000420"
     CDS             complement(4813..6714)
                     /gene="mrdA"
                     /locus_tag="OPY25_000420"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HCS0926136.1"
                     /translation="MKRQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     LRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLNDDDIAAFKKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLDRENKLANYAATHDIGKLGIERYYEDIL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVIVT
                     DPRTGGVLSLVSMPSYDPNLFVDGISSKDYSGLLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTSLFDPGWWQLPGSEKRYRDWKKWGHGHLNITKSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFSYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGVVKVPHLLMSTAENGKQVPWVQPHEPPVGDIH
                     SGYWEIAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAIILENGGAGPAVGTIMRQILDHIMLGDNNTHLPAEN
                     PVVAAAEDQ"
     gene            complement(6745..7212)
                     /gene="rlmH"
                     /locus_tag="OPY25_000421"
     CDS             complement(6745..7212)
                     /gene="rlmH"
                     /locus_tag="OPY25_000421"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCS0926137.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            complement(7216..7533)
                     /gene="rsfS"
                     /locus_tag="OPY25_000422"
                     /gene_synonym="rsfA"
     CDS             complement(7216..7533)
                     /gene="rsfS"
                     /locus_tag="OPY25_000422"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCS0926138.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQSSRAAGMLPLGVEGENAADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            complement(7862..8470)
                     /locus_tag="OPY25_000423"
     CDS             complement(7862..8470)
                     /locus_tag="OPY25_000423"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HCS0926139.1"
                     /translation="MRLWLVRHGETEANVAGLYSGHAPTPLTEKGIGQAKTLHTLLRH
                     APFDRVLCSELERARHTARLVLEGRDTPQHILPELNEMYFGDWEMRHHRDLTHEDAES
                     YAAWCTDWQNAVPTNGEGFQAFTRRVERFISRLGAFSDCQNLLIVSHQGVLSLLIARL
                     LAMPAASLWHFRVEQGCWSTIDICEGFATLKVLNSRAVWRPE"
     gene            8567..9661
                     /locus_tag="OPY25_000424"
     CDS             8567..9661
                     /locus_tag="OPY25_000424"
                     /EC_number="4.1.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine-phosphate decarboxylase"
                     /protein_id="HCS0926140.1"
                     /translation="MALFNSAHGGNIREAATVLGISPDQLLDFSANINPLGMPVSVKR
                     ALIDNLDCIERYPDADYFHLHQALARHHQVPASWILAGNGETESIFTVASGLKPRRAI
                     IVTPGFAEYGRALAQIGCEIRRWSLREADGWQLTDAILEALTPDLDCLFLCTPNNPTG
                     LLPERQLLQAIADRCKSLNINLILDEAFIDFIPHETGFIPALKDNPHIWVLRSLTKFY
                     AIPGLRLGYLVNSDDAAVARMRRQQMPWSVNALAALAGEVALQDSAWQQATWHWLREE
                     GARFYQALCQLPLLTVYPGRANYLLLRCEREDIDLQRRLLTQRILIRSCANYPGLDSR
                     YYRVAIRSAAQNERLLAALRNVLTGITPAD"
     gene            complement(9636..10277)
                     /gene="nadD"
                     /locus_tag="OPY25_000425"
     CDS             complement(9636..10277)
                     /gene="nadD"
                     /locus_tag="OPY25_000425"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCS0926141.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLSRVIIMPNNVPP
                     HRPQPEASSAQRKYMLELAIADKPLFTLGERELQRNAPSYTAQTLKAWREEQGPEAPL
                     AFIIGQDSLLNFPTWHDYDTILDNTHLIVCRRPGYPLEMTQAQHQQWLEQHLTHTPDD
                     LHQLPAGKIYLAETPWLNISATLIRERLEKGESCDDLLPENVLNYINQQGLYR"
     gene            complement(10279..11310)
                     /gene="holA"
                     /locus_tag="OPY25_000426"
     CDS             complement(10279..11310)
                     /gene="holA"
                     /locus_tag="OPY25_000426"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCS0926142.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAIRLAAAS
                     QGFEEHHAFTLDPSTDWGSLFSLCQAMSLFASRQTLVLQLPENGPNAAMNEQLATLSE
                     LLHDDLLLIVRGNKLTKAQENAAWYTALADRSVQVSCQTPEQAQLPRWVAARAKAQNL
                     QLDDAANQLLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRPMIGDALQRLHPAQLRQAVQLLTRTEITLKQDYGQSVWADLEGLSLLLCHK
                     ALADVFIDG"
     gene            complement(11310..11900)
                     /gene="lptE"
                     /locus_tag="OPY25_000427"
     CDS             complement(11310..11900)
                     /gene="lptE"
                     /locus_tag="OPY25_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HCS0926143.1"
                     /translation="MRYLVTLLLSLAVLVTAGCGWHLRSTTQVPASMKTMILDSGDPN
                     GPLSRAVRNQLRLNNVNLLDKDTTRKDVPSLRLGTVTISQDTASVFQDGQTAEYQMVM
                     TVNASVLIPGHDIYPISTKVYRSFFDNPQMALAKDNEQAMIVQEMYDKAAEQLIRKLA
                     SVRAADIQATKEEATADNETAAPASTPARVSTTLSN"
     gene            complement(11915..14497)
                     /gene="leuS"
                     /locus_tag="OPY25_000428"
     CDS             complement(11915..14497)
                     /gene="leuS"
                     /locus_tag="OPY25_000428"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCS0926144.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVVARYQHMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNA
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAF
                     EAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQY
                     QEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTA
                     KGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     QEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVEN
                     TTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            14734..15075
                     /locus_tag="OPY25_000429"
     CDS             14734..15075
                     /locus_tag="OPY25_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCS0926145.1"
                     /translation="MARLLIREDRTKAKELIVKKNAVVIHPQDCVATAITALKAGETA
                     TMFIGEREISVVLHQDVPFGHKFAICDVPFHGEVYKYGESIGRATQEIKSGDYVHVHN
                     VESERGRGDWK"
     gene            15092..16264
                     /locus_tag="OPY25_000430"
     CDS             15092..16264
                     /locus_tag="OPY25_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCS0926146.1"
                     /translation="MIMSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQV
                     KGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVGAIVVVGLGCEGAEPLRIAEEIT
                     AFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSD
                     TTSGLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVV
                     GCEARAKALGEDIRGGQPTPGSIKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTH
                     PGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIKITGNKATWEMMQ
                     DNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF"
     gene            16314..17267
                     /locus_tag="OPY25_000431"
     CDS             16314..17267
                     /locus_tag="OPY25_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease 2"
                     /protein_id="HCS0926147.1"
                     /translation="MKIKKTLERFPGGMMVVPLIIGALFKTFAPEALEIGGFVISISH
                     GAMAILGMFLVCMGADIQFKAAPKALKKGAAITFAKFASGVIIGILVGKFCGPDGLLG
                     LSALAIISAMTNSNSGLYAALVGEYGDETDGGAIAVISLNDGPFFTMLALGSAGMVSI
                     PFMNLVAVIIPIIIGMILGNLDEDMRKFLKQGSVVTIPFFAFGLGYSIDFARLITAGS
                     SGILLGLMTVAIGGFFNIFADRVTGGSGVAGAAVSTTSGNAVATPAAIALLDPHFTDL
                     ASTAAAQVAASTIITALCAPFLTVWIKKRYDRKLNPAAAGG"
     gene            17335..19263
                     /locus_tag="OPY25_000432"
     CDS             17335..19263
                     /locus_tag="OPY25_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HCS0926148.1"
                     /translation="MNKTKDIAASPLCFVSPYPQLAKAAEALVAQLDYAVTIHQTTLN
                     RILDELPLLESRGHQVLISRGGCAEILKKHSKLPVVEIKMSGYDILDALIPFKGQKGT
                     VGIVGFSSVIKGCARVAEQLNINYKIFTLQGNDKETISCLKRQLASTPLDCIVGDTVC
                     QDYFSPLGSQFRLLDSSPASITEALEEARSLYLAFRSQLLERHHLQLILDQFDKAVIT
                     LDDTGALLHYNKYASQLFKINASGEIYDASFLKQVLHQERHTLREGKTVSAKVVDTPQ
                     GAMVVNLYPVFAARQLSRVVLTMQTVSSLQGAEHHVRRQELSRRGLSARYHFDDLLTE
                     NPEMLRRLAIIKNYAGTDATILINGESGTGKEVLAQSIHNASQRVNGLFVAINCGAMA
                     TQILESELFGYVAGAFTGASPKGKIGLFELAHHGTIFLDEISELDKPLQTRLLRVLQE
                     RQIMRLGSDQMIPVDIRVIAATNQTLTKLIADGTFREDLYYRLNVLKVTTIPLRKRPE
                     DIKAIGLSLLTSFSQHYKRPALTLTPALWQELQRFAWPGNVRQLSNIIERLVLSIDHS
                     PATLDEGRLLLDDLEEGSRREPSTCHDCQMLAGDYKTIRLRILRKLLEAERDNKSLVA
                     KRLNVDRTSLTRWIRESA"
     gene            19356..19829
                     /locus_tag="OPY25_000433"
     CDS             19356..19829
                     /locus_tag="OPY25_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HCS0926149.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARQRVMQTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESQEDSVFLRVIKESLWQELADITDKTQLEWREVF
                     QDLNHHGVYHSGEVVGLGNLVCEKCHYHLAVYTPDVLPLCPKCGHDQFQRRPFEP"
     gene            complement(19868..20161)
                     /locus_tag="OPY25_000434"
     CDS             complement(19868..20161)
                     /locus_tag="OPY25_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001785127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926150.1"
                     /translation="MLRPCIIHDPDSDAGIHMLSWHGSPLIRFYTEAWCPTCAEFVYA
                     GFSNDDEGAAQFLSSLAEWNQPGVGLNEAFTALTPLFSLFADGYYRLEAQLHS"
     gene            complement(20280..21215)
                     /gene="rihA"
                     /locus_tag="OPY25_000435"
     CDS             complement(20280..21215)
                     /gene="rihA"
                     /locus_tag="OPY25_000435"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HCS0926151.1"
                     /translation="MALPIIIDCDPGHDDAIALVLALASPELEVKAITSSAGNQTPEK
                     TLRNVLRMLTLLKRPDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPSFAPQSG
                     TAVELMAKTLRESAQPVTIVSTGPQTNVALLLNSHPELHTKIARIVIMGGAMALGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHAADIERFRDIGNPISTIVAE
                     LLDFFFEYHKDEKWGFVGAPLHDPCTIAWLLKPEIFTTVERWVGVETQGKYTQGMTVV
                     DYYFLTGNKPNATVMVDVDRQGFVDLLAERLQYYA"
     gene            complement(21332..22057)
                     /gene="gltL"
                     /locus_tag="OPY25_000436"
     CDS             complement(21332..22057)
                     /gene="gltL"
                     /locus_tag="OPY25_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HCS0926152.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQKGEITVNGIIVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAAARDKGLKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKEEFFANPSSDRAKDFLAKILH"
     gene            complement(22057..22731)
                     /gene="gltK"
                     /locus_tag="OPY25_000437"
     CDS             complement(22057..22731)
                     /gene="gltK"
                     /locus_tag="OPY25_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HCS0926153.1"
                     /translation="MYEFDWSSIIPSLPYLLAGLVITLKITVTAVVVGIVWGTILAVM
                     RLSSFAPIAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKTDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGAVYFVISLSASLLVSY
                     LKKRTV"
     gene            complement(22731..23471)
                     /gene="gltJ"
                     /locus_tag="OPY25_000438"
     CDS             complement(22731..23471)
                     /gene="gltJ"
                     /locus_tag="OPY25_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HCS0926154.1"
                     /translation="MSIDWNWGIFLQEAPFGNTTYLGWLWSGFQVTVALSITAWIIAF
                     LVGSIFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVVPELLPEDLGMWFKA
                     ELDPNIQFFLSSMICLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAVIMLVMSLVERKVRLPGNVGSK"
     gene            complement(23631..24539)
                     /locus_tag="OPY25_000439"
     CDS             complement(23631..24539)
                     /locus_tag="OPY25_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCS0926155.1"
                     /translation="MQLRKLTTAMLVMGLSAGLAHAEDGAPAAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEVVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNLERQKQAAFSDTIFVVGTRLLTKKGGDIKDFPDLKGKAVVVTS
                     GTTSEILLHKLNEEQKMGMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKNDPEFKKLMDDTIAQAQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKAPNDKALN"
     gene            complement(24957..26495)
                     /gene="lnt"
                     /locus_tag="OPY25_000440"
     CDS             complement(24957..26495)
                     /gene="lnt"
                     /locus_tag="OPY25_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HCS0926156.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGL
                     QALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLS
                     LYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPL
                     KGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEP
                     TKATQVSLVQGDIPQSLKWDENQLLNTLNIYLNETRPELGKSQIIIWPESAIPDLEIN
                     QQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTRQVLTTKVTPTTGLTPYARTGDWTVWLITVLFGFGALVMSLR
                     QRRK"
     gene            complement(26515..27393)
                     /gene="corC"
                     /locus_tag="OPY25_000441"
     CDS             complement(26515..27393)
                     /gene="corC"
                     /locus_tag="OPY25_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459659.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HCS0926157.1"
                     /translation="MSDDNSHSSDTVNSKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNELIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRTAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTIRALA
                     SIEDFNDAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVRIPDDSPQPKLDE"
     gene            complement(27551..28024)
                     /gene="ybeY"
                     /locus_tag="OPY25_000442"
     CDS             complement(27551..28024)
                     /gene="ybeY"
                     /locus_tag="OPY25_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCS0926158.1"
                     /translation="MSQVILDLQLACENHAGLPDEAQFQRWLDGVIPQFQEEAEVTIR
                     LVDEAESHDLNLTYRGKDKPTNVLSFPFEAPPGIEMPLLGDLIICRQVVEQEAQEQSK
                     PLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKIAE"
     gene            complement(28021..29067)
                     /locus_tag="OPY25_000443"
     CDS             complement(28021..29067)
                     /locus_tag="OPY25_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCS0926159.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAATDILRSLYVDTAPMRGQTQDIEPEQIHLAIKEARVLEQSAESV
                     PDYGKAINIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLAEVDEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREAQEQEQK"
     gene            complement(29272..30696)
                     /gene="miaB"
                     /locus_tag="OPY25_000444"
     CDS             complement(29272..30696)
                     /gene="miaB"
                     /locus_tag="OPY25_000444"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HCS0926160.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWRLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRVLNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKNIMELSGRTENNRVVNFEGTPEMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENELGVGFYQP"
     gene            30840..32015
                     /gene="ubiF"
                     /locus_tag="OPY25_000445"
     CDS             30840..32015
                     /gene="ubiF"
                     /locus_tag="OPY25_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HCS0926161.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQQGFTVMVIEHAAPAPFVA
                     DSQPDVRISAISAASVALLKGLGVWEAVQGMRSHPYRRLETWEWENAHVVFDAAELKL
                     PLLGYMVENNVLQQALWQALEAHPGVTLRVPASLAALHRRHDGYALELADGEWVTPKL
                     VIGADGANSQVRQMAGIGIHAWQYAQSCMLITVKCENAPGDSTWQQFTPTGPRAFLPL
                     FDDWASLVWYDAPARIRQLQSLSMTQLQVEINQHFPARLGAVMPVAAGAFPLTRRHAL
                     QYAQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLASARSYGESWASHSVLKRY
                     QTRRMADNFMMQSGMDLFYAGFSNELPPLRILRNMGLMAAQRAGVLKRQALKYALGL"
     gene            complement(32148..32222)
                     /locus_tag="OPY25_000446"
     tRNA            complement(32148..32222)
                     /locus_tag="OPY25_000446"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32188..32190),aa:Gln,seq:ctg)
     gene            complement(32269..32345)
                     /locus_tag="OPY25_000447"
     tRNA            complement(32269..32345)
                     /locus_tag="OPY25_000447"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32309..32311),aa:Met,seq:cat)
     gene            complement(32361..32435)
                     /locus_tag="OPY25_000448"
     tRNA            complement(32361..32435)
                     /locus_tag="OPY25_000448"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32401..32403),aa:Gln,seq:ttg)
     gene            complement(32471..32545)
                     /locus_tag="OPY25_000449"
     tRNA            complement(32471..32545)
                     /locus_tag="OPY25_000449"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32511..32513),aa:Gln,seq:ttg)
     gene            complement(32569..32653)
                     /locus_tag="OPY25_000450"
     tRNA            complement(32569..32653)
                     /locus_tag="OPY25_000450"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32617..32619),aa:Leu,seq:tag)
     gene            complement(32662..32738)
                     /locus_tag="OPY25_000451"
     tRNA            complement(32662..32738)
                     /locus_tag="OPY25_000451"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32702..32704),aa:Met,seq:cat)
     gene            complement(32960..34624)
                     /gene="asnB"
                     /locus_tag="OPY25_000452"
     CDS             complement(32960..34624)
                     /gene="asnB"
                     /locus_tag="OPY25_000452"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HCS0926162.1"
                     /translation="MCSIFGVFDIKTDAAELRKKALELSRLMRHRGPDWSGIYACDNA
                     ILAHERLSIVDVNAGAQPLYNAKKTHVLAVNGEIYNHQTLRAEYGDRYAFQTGSDCEV
                     ILALYQEKGPDFLDDLQGMFAFALYDSEKDAYLIGRDHIGIIPLYMGYDEFGNFYVAS
                     EMKALTPVCRTIKEFPAGSYLWSKDGEIRQYYQRDWFDYDAVKDNVTDKNALRQALEE
                     SVKSHLMSDVPYGVLLSGGLDSSVISAITKKFAARRVEDQERSEAWWPQLHSFAVGLE
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLQALHMYDCTRANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHVLRECFESYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAKQISDQQLETARFRFPYNTPSSKEAYLYREIFEELFPV
                     PSAAECVPGGPSVACSSAKAIEWDEAFKTMDDPSGRAVGVHQSAYQ"
     gene            complement(34914..35666)
                     /gene="nagD"
                     /locus_tag="OPY25_000453"
     CDS             complement(34914..35666)
                     /gene="nagD"
                     /locus_tag="OPY25_000453"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HCS0926163.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLTGILEKGLPLVLLTNY
                     PSQTGQDLANRFATAGVNVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAFFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSTINDIDSMPFRPSWIYPSVAEIDVI"
     gene            complement(35713..36933)
                     /gene="nagC"
                     /locus_tag="OPY25_000454"
                     /gene_synonym="nagR"
     CDS             complement(35713..36933)
                     /gene="nagC"
                     /locus_tag="OPY25_000454"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HCS0926164.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQHGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDTTLTL
                     YDLSSKVVAEEHYPLPERTQETLEHALLNTIAVFIDSCQRKIRELIAISVILPGLVDP
                     ESGVIRYMPHIQVENWGLVEALEKRFHVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANRGDSLASEVIEHVGRHLGKTIAIAINLFN
                     PQKIVIAGEIIEADKVLLPAIESCINTQALKAFRKNLPVVRSTLDHRSAIGAFALVKR
                     AMLNGTLLQRLLES"
     gene            complement(36938..38092)
                     /gene="nagA"
                     /locus_tag="OPY25_000455"
     CDS             complement(36938..38092)
                     /gene="nagA"
                     /locus_tag="OPY25_000455"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCS0926165.1"
                     /translation="MYALTQGRIFTGHEILDDHALVVANGLIDRVCPMAELPPGIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNFLPTLITT
                     SDELMKQGIRVMREYLEKHPHQALGLHLEGPWLNLVKKGTHNPDFVRKPDAALVDFLC
                     DNADVITKVTLAPEMVPADVIAKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLF
                     NAMPYITGREPGLAGAVLDEADIYCGVIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVAHCGIALDEVLRM
                     ATLYPARAIGVDKHLGSIAPSKVANLTAFTHDFKIIKTIVNGDEVVDLSK"
     gene            complement(38152..38952)
                     /gene="nagB"
                     /locus_tag="OPY25_000456"
     CDS             complement(38152..38952)
                     /gene="nagB"
                     /locus_tag="OPY25_000456"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCS0926166.1"
                     /translation="MRLIPLSTAEQVGKWAARHIVNRINAFKPTTDRPFVLGLPTGGT
                     PLTAYKALVEMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEG
                     NVNHMWTISCLQLHPKAVVVCDEPSTMELKVKTLKYFNELEAENIKGL"
     gene            39279..41231
                     /gene="nagE"
                     /locus_tag="OPY25_000457"
     CDS             39279..41231
                     /gene="nagE"
                     /locus_tag="OPY25_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HCS0926167.1"
                     /translation="MNILGFFQRLGRALQLPIVVLPVAALLLRFGQPDLLNMPFIAQA
                     GGSIFDNLALVFAIGVASSWSKDSAGAAALAGAVGYFVMTKAMVTINPEINMGVLAGI
                     ITGLVGGAVYNRWSGIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHGIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAITAFLTGV
                     TEPLEFLFMFLAPLLYLLHAILTGISLFVATLLGIHAGFSFSAGAIDYVLMYNLPAAS
                     NNVWMLLVMGVVFFIIYFLLFSAVIRMFNLKTPGREDKVDEMVTEEANSNTEEGLTQL
                     ATSYIAAVGGTDNLKAVDACITRLRLTVNDSARVNDAACKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDEMKKVVARGPVAAASADAAHVATPAPAAKPQAVPNAVTIAELVSPITG
                     EVVALDQVPDEAFASKAVGDGVAVKPTDKTVVSPAAGTIVKIFNTNHAFCLETEKGAE
                     IVVHMGIDTVALNGQGFKRLVEEGAEVTAGQPVLELDLDFLNANARSKISPVVCSNSD
                     DFSALVIKADGHVVAGQTPLYEIKSK"
     gene            41442..43109
                     /gene="glnS"
                     /locus_tag="OPY25_000458"
     CDS             41442..43109
                     /gene="glnS"
                     /locus_tag="OPY25_000458"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HCS0926168.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYQGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGDIRYSSD
                     YFDQLHAYAVELINKGLAYVDELTPEQIREYRGTLTAPGKNSPFRDRSVEENLALFEK
                     MRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGTKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYPQGESEMVTMPNHPNKPEMGSREVPFSGEIWIDRA
                     DFREEANKQYKRLVMGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPAD
                     GRKVKGVIHWVSVAHALPIEIRLYDRLFSVPNPGAAEDFLSVINPESLVIKQGYGEPS
                     LKAAVAGKAFQFEREGYFCLDSRYATADKLVFNRTVGLRDTWAKAGE"
     gene            43561..44967
                     /gene="chiP"
                     /locus_tag="OPY25_000459"
     CDS             43561..44967
                     /gene="chiP"
                     /locus_tag="OPY25_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HCS0926169.1"
                     /translation="MRTFSGKRSTLALAIAGITAMSGWIVVPQAQASGFFDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHATWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSGHPNEIAFSKKNKGYDEDYSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGASFDYGDAGALSFSYMWTNEYKAPWHTEMDKFYQADKKTNV
                     DYLHSIGAKYDFKNDLVLEAAFGQSEGYVDQYFAKASYKFDLGGNPFTTSYQFYGARD
                     KVDDRSVNDIYDGTAWLQALTFGYKVAEVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGWAVGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESSYSLDAVYTLQEGRAKGTMFKLHFTEYDNHSNIPSWGGGYGNI
                     FQDERDVKFIVIAPFTIF"
     gene            45017..45349
                     /locus_tag="OPY25_000460"
     CDS             45017..45349
                     /locus_tag="OPY25_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0926170.1"
                     /translation="MKKILLIASMTAGLTACASSPAPEEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKERKHQQFANEESVRVLDYQQCIQATRTGNDQAVKADCDKVWQE
                     IRSHNNVQ"
     gene            complement(45398..46702)
                     /gene="tcuC"
                     /locus_tag="OPY25_000461"
     CDS             complement(45398..46702)
                     /gene="tcuC"
                     /locus_tag="OPY25_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tricarballylate/proton symporter TcuC"
                     /protein_id="HCS0926171.1"
                     /translation="MAQHTPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIART
                     FFPAESEFASLMLTFAVFGSGFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLL
                     IALVPGYQTIGLAAPALVLLGRLLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSA
                     SQQVAIVVAALIGYSLNITLGHDAISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFL
                     QRKHRPDTREIFATIAKNWRIITAGTLLVAMTTTTFYFITVYTPTYGRTVLNLSARDS
                     LIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGITLLALITTWPVMQWLTAAPDFTRM
                     TLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALV
                     KLTGDKSSPGWWLMCAALCGLAATAMLFVRLSRGYIAAENKA"
     gene            complement(46753..47892)
                     /gene="tcuB"
                     /locus_tag="OPY25_000462"
     CDS             complement(46753..47892)
                     /gene="tcuB"
                     /locus_tag="OPY25_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tricarballylate utilization protein TcuB"
                     /protein_id="HCS0926172.1"
                     /translation="MKQLEKLIIEATVLTEPEAEVERVMQVCNACRYCEGFCAVFPAM
                     TQRLEFGKADIHYLANLCHNCGACLHACQYAPPHEFAINVPKAMAQARLETYQQYAQP
                     AAFGALYRRAGITVALALIVGLTLFLLLAMALKGSLIHPPLAGDFYQIFPHSLLAWMF
                     GSVFVLAIGLLMAGVISFWREISPGVPRSAEIAEASHNALTLKYLDGGHGKGCNEADD
                     AFTLLRRRFHHFTFYGFMLCFAATVVATGYHYVAGWEAPYPFFSLPVMLGTLGGIGLL
                     IGPAGLLWLNLRRSPLHSDARQKPMDRGFILLLFLTSLTGLALLAGRDTSGMGILLAL
                     HLGVVMALFLTLPYGKFAHGFFRCAALLKWAVEKRRGKHAGDTGN"
     gene            complement(47879..49282)
                     /gene="tcuA"
                     /locus_tag="OPY25_000463"
     CDS             complement(47879..49282)
                     /gene="tcuA"
                     /locus_tag="OPY25_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent tricarballylate dehydrogenase
                     TcuA"
                     /protein_id="HCS0926173.1"
                     /translation="MVDVLVIGGGNAALCAALTAREAGASVLLLEAAPREWRGGNSQH
                     TRNLRCMHDAPQDVLVESYPEEEFWQDLWRVTDGNTNEALARLVIRTSSQCRDWMRKH
                     GVNFQPPLSGALHVARTNAFFMGGGKALVNAYYRSAERLGVQIRYNTPVHALELHDGE
                     FVAALAGSERITAKACVLAAGGFESNREWLREAWGENARGEWPADNFLIRGTRFNQGV
                     LLKFMMDAGADIIGDPSQSHCVAIDARAPLYDGGICTRVDCVSLGIVVNRDAERFYDE
                     GEDFWPKRYAIWGRLVAQQPGQIGYSIIDSKAIGHFMPPVFPGAQANTLAELACQLGL
                     DAEKFTHTVTQYNQACQPGHFDHTLLDDCATKNLTPAKTHWARPLDAPPYYGYALRPG
                     ITFTYLGLKVNERAAVHFAGHPSRNLFVAGEMMAGNVLGKGYTAGVGMSIGTTFGRIA
                     GIEAARAAHKEAQHETA"
     gene            complement(49380..50306)
                     /gene="tcuR"
                     /locus_tag="OPY25_000464"
     CDS             complement(49380..50306)
                     /gene="tcuR"
                     /locus_tag="OPY25_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tricarballylate utilization LysR family
                     transcriptional regulator TcuR"
                     /protein_id="HCS0926174.1"
                     /translation="MELRQLRYFVRIIETGSMGSAAQDLDIGVSALSQQMSRLENELA
                     IRLLQRTSRGVTPTNAGLAFYSQAQLALRHADDAILAAREARLSGHVSVGMAPSTASI
                     LGIPFIHAMQENYADVRLHVVESLSGNLERMINTRQIDLAVVFQKDKILRWSARPILE
                     EQLFLIGSHALLAALPDNPITPEQLAGIPLIMPSQGHGLRGRLDAVCKEHALNVEIVA
                     EIDGLALLMRAVRDGLGATLQPGAAISHLDNDALRVIGVHNPVLSRPNFLVSLSDDEL
                     TPAGLAARVVLTKVMRQLVDAGEWPGATLYAY"
     gene            complement(50421..50873)
                     /gene="fur"
                     /locus_tag="OPY25_000465"
     CDS             complement(50421..50873)
                     /gene="fur"
                     /locus_tag="OPY25_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HCS0926175.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHDDATK"
     gene            complement(50866..50951)
                     /locus_tag="OPY25_000466"
                     /pseudo
     CDS             complement(50866..50951)
                     /locus_tag="OPY25_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ryhB-regulated fur leader peptide"
     gene            complement(51155..51685)
                     /gene="fldA"
                     /locus_tag="OPY25_000467"
     CDS             complement(51155..51685)
                     /gene="fldA"
                     /locus_tag="OPY25_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HCS0926176.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EGYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQVSAELHLGDILNA"
     gene            complement(51836..52129)
                     /gene="ybfE"
                     /locus_tag="OPY25_000468"
     CDS             complement(51836..52129)
                     /gene="ybfE"
                     /locus_tag="OPY25_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HCS0926177.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAQAVDALNELAEARNISRSELIEEILMKQLMALRGQGLV"
     gene            complement(52263..53033)
                     /gene="ybfF"
                     /locus_tag="OPY25_000469"
     CDS             complement(52263..53033)
                     /gene="ybfF"
                     /locus_tag="OPY25_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCS0926178.1"
                     /translation="MKLNIRAQSAQNLHNNSPIVLVHGLFGSLDNLGVLARDLVTDHD
                     IIQVDMRNHGLSPRDPVMDYPAMAQDLLDTLDAQQIEKATFIGHSMGGKAVMALTALA
                     PDRIDRLVAIDIAPVDYHVRRHDRIFAAINAVSESDATSRQQAAGIMRQHLNKEGVIQ
                     FLLKSWAEGEWRFNVPVLWEQYPHIVGWETIPPWEHPALFIPGGNSPYVTEAYRDALL
                     AQFPLARAHVIAGAGHWVHAEKPEAVLRAIRRYLHDKR"
     gene            53218..53760
                     /gene="seqA"
                     /locus_tag="OPY25_000470"
     CDS             53218..53760
                     /gene="seqA"
                     /locus_tag="OPY25_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HCS0926179.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSATTQPTAS
                     AMKGTPAAQPVAEAKPVNPVKDKVRAMRELLLSDEYAEQKKAVNRFMLILTTLYSLDH
                     HAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMIE
                     HIMQSMQFPAELIEKVCGTI"
     gene            53785..55425
                     /gene="pgm"
                     /locus_tag="OPY25_000471"
     CDS             53785..55425
                     /gene="pgm"
                     /locus_tag="OPY25_000471"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HCS0926180.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAGRHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALLADGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPLWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAARFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(55540..56025)
                     /locus_tag="OPY25_000472"
     CDS             complement(55540..56025)
                     /locus_tag="OPY25_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HCS0926181.1"
                     /translation="MSNPEREVTDIAEILAILSKHEVCRIGFNDNLCPYVVPVNFGYE
                     YQNGRWIFYFHGARTGKKMRLLRKNPAVCIEMDGDHALLRADDPCDYSYAYTSVFATG
                     LASILQTREEMRHGLDVIMRQTDPGKTFSYREDMMKAVCVVRIECDALTCRRHLATQS
                     E"
     gene            complement(56090..57409)
                     /gene="potE"
                     /locus_tag="OPY25_000473"
     CDS             complement(56090..57409)
                     /gene="potE"
                     /locus_tag="OPY25_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HCS0926182.1"
                     /translation="MSKPKSNKMGVVQLTILTMVNMMGSGIIMLPTKLSEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELFGAALTPLQIGLATIAVLWVCTIANFGGARITGQISSVTVWGVIIP
                     VVGLCIIGWFWFSPSMYVASWNPHHVPFFSAVGSSIAMTLWAFLGLESACANADVVEN
                     PEKNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMDLANSTAPFGLAFAQMFTPAVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSADEGYFPKVFSRVTKVDAPVQGMLIIVIIQT
                     GLSLMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKMANVPSSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            complement(57406..59474)
                     /locus_tag="OPY25_000474"
                     /pseudo
     CDS             complement(57406..59474)
                     /locus_tag="OPY25_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
     gene            complement(59857..59958)
                     /locus_tag="OPY25_000475"
                     /pseudo
     CDS             complement(59857..59958)
                     /locus_tag="OPY25_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2618 domain-containing protein"
BASE COUNT        13981 a        15738 c        16315 g        14059 t
ORIGIN      
        1 cgaaaatata gaaagcgggg ggagaagtaa agcattcaaa tcatatatga ttaatgaccc
       61 ataaatttct tgggccatta tattttacgc attaagtagc aatatattca tacggtggat
      121 tatttagcag agctaaaata ttcgccagca agcggggcgc aatattatct gtggtagcgt
      181 cttccttcca ctgcgttatt ttagccattt ccatgccggc ataaccacac gggttgatgc
      241 gtaggaaagg agaaagatcc atgttaacgt ttagcgctaa accgtggaat gagcagccgc
      301 gacggatacg taaacccagc gagcagattt tcttttcacc cacgtagacg cccggcgcat
      361 cggcgcgcgg atgcgcctca atacccattt cagccagcgt attcaccacg gtctgttcaa
      421 gtagggtgac taaatcacgc acgcccagtt tacgtcgttt caggttaagt aaaacgtaca
      481 ttacctgttg gcccggacca tgataggtca cctgtcctcc acgatcgctc tgcacaacgg
      541 gaatatcgcc aggcatcaat atatgttccg ctttaccggc ctggccctgg gtaaacaccg
      601 ggtaatgctc aaccaaccag atttcatcat ggctgttttc atcgcgcata tcggtaaagt
      661 tatgcatggc ctgagagata gcttcatagg gctgaaggcc gagctggcgg acaaggattt
      721 tatcctgata caaaacggca tctccgtaga gaatgaaaaa agagaggaaa gtatatcaca
      781 gcgggggagg cggggagtta cccggataag accgggtaac cgtctggatg tattacaata
      841 ccattcgcac gatatcaata ttacccagtt cttcgtacaa cgtttcaacc tgttcaatat
      901 gggtggcatt aatggtgata gagaccgagt ggtagttgcc tttgctgctc ggttttaccg
      961 tcggagagta atcaccaggc gcatggcgct gtaccacttc aaccacctga tcaaccagct
     1021 caggtaacgc ctgccccatt actttgtaag taaatggcgt agggaattca agcagttcgt
     1081 taagtttggt tttcatgtca gctccggcat tacgtaaaaa aataacaact cccgccacag
     1141 ggcgggagtt ttactgatgc atagtatatg gggacgaaaa tcacactttc aagcgttcaa
     1201 tttttatcca aaccagtgat ggaacattaa tttaatgtaa tcaatgattt taccgaagaa
     1261 gttcccttcc gggatctctt gcagtacgac cagcggacgc tgctcgatgg ttttaccgtc
     1321 cagctggaag ttgatggtgc cgaccacctg gtttttctgc agcggcgcgt gcagttctgc
     1381 ggtattcagt acatagctcg ctttcaaatc tttcatgcga ccgcgaggga tcgtcaggta
     1441 aacgtcttta tcgacgccca gcgaggcgcg atcggtatta ccaaaccagg cgggttcaga
     1501 ggcgaactct ttaccagcct tcagcggatt aacggtttca aagaaacgga agccccacgt
     1561 cagcagtttt ttgctttctg tttcacggcc tttataggtc cgtccgccca ttacggcgga
     1621 aatcaatcgc atctggcctt cggttgcgga agcgaccaga ttatagcccg ctttgctggt
     1681 atggccggtt ttgatgccgt ccacattcag gctgttatcc cacagcagac cgttacggtt
     1741 taactggcga atgccgttaa aggtgaactc tttttcttta taaacggcat attcgttcgg
     1801 cacatctcga attaacgcct ggccaatcag cgccatatcg cgagctgaac tgtattgtcc
     1861 gtcggcgtcc aggccgtgta cggtctggaa gtgggtattt ttcagcccca acgcgttcac
     1921 atagctgttc atcagcccga cgaaagcatc ctggctaccg gcggcgaaat cagccatcgc
     1981 cacacaggcg tcattgccgg attgcagatt gatgccgcgt atcaactgag agaccggtac
     2041 ctgcattccc ggtttgagga acatcagcga agagccttta aataccggat tgccggtggc
     2101 ccaggcgtca ttaccgacgg taaccaggtc ggtttcttta aatttacccg ctttcattgc
     2161 ctgtccgatg acgtaactgg tcatcatctt cgtcagacta gccgggtcgc gacgttcgtc
     2221 ggcgttttgt tccgccagaa ctttgccgga gttgtagtcg atcaggatgt aggattccgc
     2281 atcgatctgc ggaacacccg ggatcatagt tttgatattc aggtcatcgg catgtgcggt
     2341 tgagataaac gtggcacaaa gcgccgtggt gagcgccatg cgctgcataa aacgagcgga
     2401 aaaagtggtc ttcatggtct gaactacgac gtccgtgatg aaattaaaaa agagccctac
     2461 tatagcaaaa gcataactgg caggcatctg actttccgcg tgactttgtt aatgtcattt
     2521 acagaaattg acagtacaga tacctgcaat cggttactgc gcgctggcga taaaggactg
     2581 taattgtgct tctgtttgca aacgttgctg taacgcgctg gcttcggctt tactggcaaa
     2641 aggccccagt tgaatacgcc agaccgcgcc gttttgtatt acgcgtcctg gtacgctgaa
     2701 ctgctggctt aaacgctgtt ggtactgctg cgcacgcgtt tgatcgctga cggcgccgac
     2761 ttggacgacg aaacgaccgc tcgccgcggc ggcaggcgcg ctcaccgggg cagataccgg
     2821 ggctgcggcg gcaggcgcgc tcaccggcgt cgcagtcgct ggagccgtca ccggcgcgga
     2881 aaccggcgct gtctgtggcg ccggcgtcgg ttcattaccc tccagcacgc caggcgccag
     2941 cgtggtcggc gcgccgagga agccgctgct gctcaccggc gcaccggtgg tatcgtcact
     3001 tttcaacgtg gaattactga ccggaagaac gtcgccttgc ggttgcgcag gcgctgaaga
     3061 ggcgcttccc atgccgccgc ttaaatcagg gcgcgggggc agagcgtagg tctgtttcgc
     3121 caccgtcgta caggccatcc ccgggccgga gagcgaacca tccggcgcca cgataatggg
     3181 gtcaatccgt actttagtat tattcgaggt attcagacga tccgccgctg cgcgggacag
     3241 ggagatgacc cgatcggtgc catagaggcc gcgatcgtta atacgcacga cgatcatgcg
     3301 accgttggcc aggttggtga ttcgcgcata gctggggata ggcagtgtcg gatgggcggc
     3361 ggtaagctgc atcggatcga acatctcccc ggaggcggtt aaattactgc cgggttccgc
     3421 atcataaata gcggccaggc cagcctggct aaagcgggac gggtcctgaa cgattttata
     3481 acttttaccg tcacgctgat aatcctggtt tgcggtcgga ttcagaggtt cataacgcgg
     3541 ttccgctccg ctgatttcca cagtcggacc attacatacc gcaggttgcg gcgcgacggt
     3601 ggtttgctgc tgaccgccgt cattagtaca tgccgcgagt agtactatcc ctgccgcgac
     3661 gcagattaca ggcaactgct tatgcattgc gcacccctta tacgcttttc gacaacattt
     3721 ttctgtgggt gtggatcgac atcacaatcc cgaacccggc catcagcaca atcagtgcgg
     3781 agcccccgta gctgaccaag ggtaaaggta ctccaaccac aggcagaata ccgctcacca
     3841 taccaatatt tacgaagaca taaacgaata atattaacat taatccgcca gccatcacgc
     3901 gaccaaatgt agtttgcgct ctggcggcaa tccacagacc gcgcattatt agcaaaatat
     3961 agagcgcgag cagaatcagg atgcccacca gaccgagctc ttccgccagt accgcgaaaa
     4021 taaagtcggt atggcgttcg ggtaaaaact ccagctgcga ctgggtgccg tggagccagc
     4081 ctttaccgcg caggccgcct gagccaatgg cgattttaga ctgaataata tgatagcccg
     4141 cgcccagcgg atcggtctcc ggatcaagga gcatcatgac gcgctggcgt tggtaatcgt
     4201 gcatcaggaa aaaccacaaa ataggaataa atgcagcgat caatacaatg gcgaccccaa
     4261 ttaagcgcca gctcaggcca gacaaaaata ggacaaagag accggaaagg gcgaccagaa
     4321 tagacgtccc caggtccggc tgggcggcga ccagcagggt aggcataaag attaatacca
     4381 gggcgatggc ggtatttttc agcgagggcg ggcagacgtc gcggttaata aagcgggcga
     4441 ccatcagcgg cacggcgatt ttggctattt ccgaaggctg aaagcgaacg attcccagat
     4501 cgagccagcg ctgcgcgccc ttggatattg cgccgaaggc atcaacggcg accagcagaa
     4561 tgatacaaat gatatagaga tagggcgccc agccttcata cacgcgcggc gggatctgcg
     4621 ccatcaccac cataaccacc agccccatcg caatctgacc gattttacgc tccatcatgc
     4681 cgatgtcctg gccgctggcg ctccagatga ccaacgcgct ataaaccagt aacgccagca
     4741 gaatgagtag catcgtggga tcgatatgaa ttttatccca gaaggttttt ttgttcggat
     4801 tatccgtcat gattattggt cctccgccgc tgcaaccacc gggttttccg caggcaaatg
     4861 ggtgttgttg tcgcccagca tgatgtgatc aaggatttgg cgcatgatcg tgcctactgc
     4921 cgggcctgcg ccgccgtttt caaggatgat cgcgacggcg acctggggat tgttatacgg
     4981 cgcaaaggcg gtcattaatt tatggtcgcg caggcgctcg gcgattttat gcgcattgta
     5041 cgtttcgttg gccttcaggc caaagacctg cgcggtgccc gacttcgccg cgattttata
     5101 gggcgcgctg gcaaaatatt tatgcgccgt gccgttaggg cggttggcga cgccatacat
     5161 gccatctttc gcaatttccc agtagccgga gtgaatatcg cccaccggtg gctcatgcgg
     5221 ctgtacccac ggcacctgtt taccgttttc cgcggtgctc attaacagat gcgggacttt
     5281 aactacaccg tcgttaataa ggatcatcag cgccttactc atctgaatcg gcgttgccgt
     5341 ccagtagccc tggccgatgc ccaccggaat cgtatcgccc tgataccacg gttttttaaa
     5401 gcgtttctgt ttccactcgc gggtcggcat attaccagag cgctcttctg cgagatcaat
     5461 tccggtatag tgaccatagc tgaacttacc catccattct gacaggcgat cgatccccat
     5521 gtcataggcc acctgataga agaaggtatc tgccgactct tcaagggatt tggtgatatt
     5581 cagatgcccg tggccccatt ttttccagtc gcggtagcgt ttctcagacc ccggcaactg
     5641 ccaccagcca gggtcgaaaa gactggtgtt acgggtgatg acgccagcgc ttaacgccga
     5701 tacggcgacg taaggcttaa cggtagaagc gggtgggtag acaccctgag tcgcgcggtt
     5761 cactaatggc gtgttcgggt cgttaagcag cccggagtaa tctttgctgg agatgccgtc
     5821 cacgaaaagg ttagggtcgt aacttggcat ggagaccagc gatagcacgc cgccggtacg
     5881 cggatcggtg acaatcaccg ccgcgcgact gcctgccagc agcgtttcaa tatactgctg
     5941 gagcttgaga tccagcgtca ggtagatatc gtgtccggcc tgcggcggca cctctttaag
     6001 ctggcgaata acgcggccgc ggttgttgac ttcaacctct tcataaccgg tttgcccatg
     6061 cagaatatct tcatagtagc gctcaatgcc cagcttgccg atgtcatggg tggcggcgta
     6121 gttcgccagt ttgttttctc tgtcgagacg ctcgacgtct ttatcattga ttttcgatac
     6181 gtagccgata acgtgggtca gcgccgatcc gtatggataa tagcggcgtt tatagccttt
     6241 gacttcgacg cccggaaaac ggtactggtt gacagcaaag cgcgcgacct gaacttccgt
     6301 caggtttgtt ttcaccggaa tagaagtaaa gcgatgggat cgggcgcgct cttttttaaa
     6361 ggcggcgata tcgtcgtcgt ttaaatcgac cacactgcgt agtgcatcca gcgtttgctg
     6421 aacgttatcc accttttccg gcatcatttc aatctgatag atagtgcggt tcagcgcaag
     6481 gggaatgccg ttgcggtcgt agattatccc gcggcttggc gcaattggca ccagcttgat
     6541 acggttttcg ttcgagcggg tctggtaatc ggtaaaacgg agaatttgca gattatacaa
     6601 attggcgatc agtacgccgg tcagcagcaa aatacccaaa aaggcgacca gcgcccgacg
     6661 cacaaacagt gcggactcag ccgtatagtc acgaaaagaa ttttgtcgtt tcatccgctg
     6721 cttaatcttc tcaagacttc acgatcactc acggtgataa gggtggttgg ttgtgatgct
     6781 ccacgcccgg tacaaactct ccgcgaccag aacccgaacc agcgggtgag ggagcgttaa
     6841 cgccgagagc gaccagctct gttccgctgc cgctttgcag gcgggagata atccttccgg
     6901 gccgccaatc agcaaactga cgtcgcgccc gtcctgtttc cagcgctcca gctcattggc
     6961 taactgcggc gtatcccacg gcttgcctgg aatatccagg gtaacaatgc gattcttacc
     7021 ggcggcggcc agcatctgct cgccctcttt gtcgagaatg cgtttgatat ccgcgttctt
     7081 gccgcgtttg cccgcaggga tttcgatcag ctcaaagggc atatctttcg gaaaacgacg
     7141 cagatattcc gtaaatcccg tttgaaccca gtcgggcatc ttcgtgccga cagcgacaag
     7201 ttgcagcttc acgcattaac tccagagttt ttccagttca tacaggcggc gactttcttc
     7261 ctgcatgaca tgcacaatca catcgcccag atcgacgaca atccagtcag ccgcattttc
     7321 gccttcgacg cccaacggca gcataccggc cgcgcgcgac gactgcacca cgtggtcggc
     7381 aatagacata acgtgacggc tggaggtgcc ggtacaaata atcatacagt cggtgatact
     7441 ggatttaccc tgaacatcta aggcgatgat gtcctgacct ttcaggtcat caattttatc
     7501 gataacaaaa tcctggagtg ctttaccctg caagttttcc ccctgggtga ataattgcgt
     7561 tataacgata gaaaaaaggc caacaggctg gaccggtaag gcgttgcgag ttaacgctaa
     7621 ccttccggcg ggacgccgtg tagtatacct gaatcagcgg cgataccggg acttatgtcg
     7681 ccggatcggc gtttaaaacc agattatcat cccatcccac gtcacagaaa gcatcgccat
     7741 ttttgtaaaa caatttctgc aaagctctgc aaggtgaaaa aagcctggct gcggagaata
     7801 acagcctgtc gggggctgtc aatgggcgaa accgctgcgg cgagaaaaaa cggaaaattc
     7861 atcactcagg ccgccagacg gcacgactat ttaatacttt cagggtggcg aacccttcgc
     7921 atatgtcgat tgtgctccag catccctgtt ctacccggaa atgccatagc gaggcggcgg
     7981 gcattgcgag caggcgggca atcaacaggc tgagtacgcc ctgatggctg acgatcagca
     8041 ggttctggca atcgctgaac gcgccgagtc gcgagataaa gcgctctacg cgccgggtaa
     8101 aagcctgaaa accctcgcca ttggtcggaa ccgcattctg ccagtccgta caccaggcgg
     8161 catagctttc ggcatcttca tgggtgaggt cgcggtgatg gcgcatttcc cagtcgccga
     8221 agtacatctc attaagctca ggtaagatgt gttgcggcgt atcccggccc tccagtacga
     8281 gccgggcggt atggcgcgcg cgctccagct cgctgcataa caccctgtca aatggcgcgt
     8341 ggcgcaataa agtatgtagc gttttcgcct ggccaatccc tttttccgtt aacggcgtgg
     8401 gagcatgtcc gctatacaac ccggcgacat tggcctcggt ttcgccatga cgcaccagcc
     8461 acaatcgcat ggtattcctc atgaggttaa atgcgcaaaa catgataatg cccctgattg
     8521 cgcaacgttt ttttcactaa aatagcgttt tttggccgga ggcataatgg cgttattcaa
     8581 cagcgcgcat ggcggtaata ttcgggaagc cgcgacggtg ttgggcatct cgcctgacca
     8641 gttactggat tttagcgcaa acattaatcc gctgggtatg cctgtcagcg tgaaacgcgc
     8701 gcttatcgac aatctggact gcattgagcg ctacccggac gccgattatt ttcatttgca
     8761 ccaggcgctg gcgcgtcatc accaggtgcc ggcatcgtgg atactggcgg gaaatggcga
     8821 gacggagtca atctttaccg tggcgagcgg tcttaaaccg cgtcgtgcaa taattgtcac
     8881 gccaggtttc gcggagtatg gccgggcgct ggcgcaaatt ggctgtgaaa ttcgtcgctg
     8941 gtctctacgc gaagcggatg gctggcagct taccgatgcc attcttgagg cgttgacgcc
     9001 cgatctggac tgcctgtttc tgtgtacgcc caataatcct accggcctgc tgccggagcg
     9061 gcagttatta caggccattg ccgatcgctg caaatcgctg aacattaacc tgatcctgga
     9121 tgaagcgttt atcgatttta ttccgcatga gacgggcttt attcctgctc ttaaagataa
     9181 tccgcatatc tgggtgctgc gttcgctgac caaattttat gccattcccg gcctgcggtt
     9241 gggatatctc gtcaatagcg atgacgcggc ggtggcgcgg atgcgtcgcc aacaaatgcc
     9301 gtggtcggtt aacgcgctgg cggcgctggc cggtgaggta gcgttacagg atagtgcctg
     9361 gcaacaggcg acctggcatt ggttacggga ggagggcgcc cggttttatc aggcgctttg
     9421 tcagcttccc ctgctgacgg tttatcccgg gcgggcaaac tatctgttgt tacgctgtga
     9481 gcgagaggat attgatctgc agcgacggtt gctgacgcag cggattttaa tccgtagctg
     9541 cgctaactac ccggggctgg acagccgcta ttatcgtgtg gcgatacgca gcgctgcgca
     9601 aaacgagcgt ctgctggcgg cgctacgcaa tgtgcttacc ggtataaccc ctgctgattg
     9661 atgtagttca gcacgttttc cggcaacaga tcgtcgcagg attcgccttt ttccagccgt
     9721 tcgcggatga gggttgcgga gatattaagc catggcgttt ccgccaggta aattttaccg
     9781 gctggcaact ggtgcagatc gtctggcgta tgggtcagat gctgttccag ccactgctgg
     9841 tgttgcgcct gcgtcatttc aagggggtag ccgggacgac gacaaacgat caggtgagtg
     9901 ttatcaagga tggtgtcgta atcatgccag gtggggaagt taagcagcga gtcctggccg
     9961 ataataaacg ccagcggcgc ttcggggccc tgttcttcgc gccatgcttt caacgtttgc
    10021 gcagtgtaag agggcgcgtt tcgctgtagc tcgcgttcac ccagcgtaaa aagcggctta
    10081 tcggcgatag ccagctccag catatattta cgctgcgcgc tggaggcttc cggctggggg
    10141 cgatgcggcg gcacattgtt aggcataata atcacccgcg ataagccgat cagattcgcc
    10201 aacgtttcaa caggtttaag atgtccataa tgcaccggat caaaggtgcc gccgaataaa
    10261 gcctgtaacg atttcatatc acccatcaat aaatacgtct gccagcgcct tatggcagag
    10321 caggagcgac agcccttcaa gatctgccca taccgactga ccataatcct gtttgagcgt
    10381 aatttctgta cgcgtcagta actgcacggc ctggcgaagc tgtgcaggat ggagacgctg
    10441 caacgcgtcg ccgatcatgg ggcgacggtt ttgccagacc cggtgtttat caaacagcgc
    10501 gcgtaacggc gtatgcgcgg actgacgttt gagatttacc agtagcagca gctctcgctg
    10561 gagggtccgc agcagaataa ccggttcgct gccttcaagg cgtagctgtt gcaggatatg
    10621 cagcgcgcgt ttgcttttcc ccatcagtaa cgcatccacc cagtggaaag gggtaaagtg
    10681 ggcggcgtca ttgacggcct gctccacgcg aggaagcgtt aacttaccgt caggccaaag
    10741 cagcgacagc cgttccagcg cctgcgccag cgccaacaga ttgccctcat agcaatagca
    10801 cagcagttgg ttcgcggcgt catccagttg caaattctgt gctttcgctc tggcggccac
    10861 ccagcgggga agctgcgcct gctccggcgt ctgacaactg acctgaacgc tacgatctgc
    10921 cagcgcggta taccaggcgg cgttttcctg cgctttggtg agcttgtttc cgcgtactat
    10981 taataacagg tcgtcatgca gtagctcgct cagggtggcg agttgctcat tcattgccgc
    11041 gttaggcccg ttttccggca gttgcagcac cagcgtttgg cggctggcga acaggctcat
    11101 cgcctggcag agtgagaaaa gcgatcccca gtcggtactg ggatcgagag taaaagcgtg
    11161 gtgctcttcg aagccttgcg acgcagccgc cagacgaata gcgtcctgac tttcctgcag
    11221 cagcagcgga tcgttgccca ataatagata tgccgcacgc agcccttcgt tgagctgcgc
    11281 gcggagttgt tcaggataca acctgatcat tagttactca gcgtagtgga gacgcgtgct
    11341 ggcgtagagg cgggcgccgc cgtctcattg tcggcggtag cctcctcttt cgtcgcctga
    11401 atatccgccg cgcggacgct ggccagctta cgaatcagct gttcagcggc tttgtcgtac
    11461 atctcctgaa cgatcatggc ctgctcgtta tccttcgcca acgccatctg cgggttatcg
    11521 aagaacgaac ggtacacttt cgtgctgata ggatagatgt catggcccgg aatcaatacc
    11581 gaggcattga cggtcatcac catctgatat tccgccgtct ggccgtcctg gaacactgac
    11641 gccgtatcct gcgaaatagt caccgttcca agccgcagag acggaacgtc tttgcgcgtt
    11701 gtgtctttat caagcaggtt tacgttattc agccgtaact gattacgtac cgcacgactt
    11761 agcggaccgt tcggatcgcc ggaatcgagg atcatcgttt tcattgaagc cggaacctgc
    11821 gtagtgctac gcagatgcca gccgcatccg gcggtgacca gcaccgccag agataacaac
    11881 agtgttacca gatatcgcac gcttcctccc gcgcttagcc aacaaccaga ttgaggagtt
    11941 tacccggaac gtaaatcact ttacgcacgg taacgccatc aagatatttt gccaccagat
    12001 gttcctggcc tgcacgttca cgcacctgtt cttcggtggc atccaccgca acggtgatct
    12061 taccgcgaac tttaccgtta acctgcacga caaccagcgt ggtgttttcc accattgcct
    12121 gctcgtcggc aaccggccac ggcgcgttgt cgatatcgcc ttcgccaccc agttcctgcc
    12181 acaaggtaaa gcagacgtgc ggggtgaacg ggttaagcat acgcacgacg gcctgcagcg
    12241 cttcctgaag cagtgcgcgg tcttgttcgc cttcctgcgg ggctttcgcc agtttgttca
    12301 tcaactccat gatcgccgca atggcggtgt tgaacgtctg acggcggccg atatcatcgg
    12361 tcactttggc aatggtttta tgcacatcgc gacgcagcgc tttttgatct tcgctcagcg
    12421 catcgacgtt cagcgccgcg acaggacctt tagcggtgtg ttcgtaaacc agcttccaga
    12481 cgcgtttaat aaagcggttt gcgccttcta cgccggactc ctgccattcc agagtcatat
    12541 ccgccggaga agcgaacatc ataaacaggc gtaccgtatc cgcgccataa cgttcaacca
    12601 ttacctgcgg gtcgataccg ttatttttcg acttggacat tttactcatg ccagtgtaga
    12661 ccagctcatg acccgctgcg tcttttgctt tgacgatgcg gcctttttca tcgcgctcga
    12721 cgatagcgtc aactggcgaa acccagttac gctcgccgtt ctcgccgaca taatagaacg
    12781 catccgccag taccatgccc tggcacagca actgtttagc cggctcgtca gaggtgacca
    12841 tgcccgcatc gcgcatcagc ttatggaaga agcggaagta gagcaggtgc atgatggcat
    12901 gttcaatacc gccgatgtag atgtcgactg gcagccagta gtttgccgct ttcgaatcca
    12961 gcattccttc ctgatactgc gggcaggtgt aacgcgcgta gtaccatgac gattccataa
    13021 aggtgtcgaa ggtgtcggtt tcacgcagcg ccggcatacc gttaacggtg gttttcgccc
    13081 actcaggatc ggccttgatc gggctggtga tgccgtccat gacgacgtct tccggcaaaa
    13141 taaccggcag ttgatcttcc ggcgtcggca gcacggtgcc gtcttccagg gtgaccatcg
    13201 ggatcggcgc gccccagtaa cgctgacggg aaacgcccca gtcacgcaga cggtagttca
    13261 ctttacgttc gccgacgcct ttttccgcca gtttatcggc aatggcgtta aacgccgctt
    13321 caaaggccag accgtcgaac tcaccggagt taaacagcac gcctttttcg gtcagcgcct
    13381 gttcggaaag atccggctcg gaaccgtcag cggccagaat caccggcttg atggtcaaac
    13441 cgtatttgga ggcaaattcg tagtcgcgct gatcgtgacc cggaacggcc atcaccgcgc
    13501 cagtgccgta ctccatcagg acaaagtttg ccgcccagac cgggatctct tcgccagtta
    13561 acggatgaat cgctttatag ccggtgtcga cgcctttttt ctccatggtc gccatttcgg
    13621 cttcggccac tttggtgtta cggcattcgt cgatgaacgc cgccagctcg gcgttgttcg
    13681 ccgccgcttt ttgcgccagc ggatgaccgg cggccactgc caggtaggtg gcgcccataa
    13741 aggtatccgg acgggtggta tagacggtca gcgtgttatc gtaacccttc acatcgaagg
    13801 tgatttccac gccttcagag cggccaatcc agttgcgctg catcgttttt acggtatcag
    13861 gccagtggtc cagcttatcc agatcgcgca acagctcgtc tgcgtaagcg gtgattttga
    13921 taaaccactg tgggatctct ttacgctcaa ctttggtgtc gcaacgccag cagcagccgt
    13981 cgatcacctg ttcgttggcg agaacggtct gatcgttcgg gcaccagtta acggcagaag
    14041 tcttcttgta caccaggcct tttttataca gctcggtgaa gaatttctgt tcccaacggt
    14101 agtattccgg ggtgcaggtc gcgatttcac ggctccagtc atagccaaaa cccagcgttt
    14161 tgagctggtt tttcatgtac gcgatgttgt cgtacgtcca cggcgccggc gcggtgttgt
    14221 tcttcaccgc cgcgccttcc gccggcaggc cgaaggcgtc ccagccgatt ggctgcagca
    14281 cgtttttgcc cagcatatgc tggtagcggg caaccacgtc gccgatggtg tagttacgta
    14341 cgtggcccat gtgtagtcgg ccagaaggat agggaagcat cgacaggcag taatacttct
    14401 ctttgctctc gtcttcggtc acttcaaatg tgcgcttctc atcccagtga agctgtactt
    14461 tggattctat ctcttccggg cggtattgct cttgcatggc agccagtagt cctgttttcg
    14521 atacagctac aaatgtagct ttagaggtgg tgtttagatc cgcatagcat agcccaaaca
    14581 cgcacgtcaa aacagggggt agaacatttg tcgcgctagg cgttcatgag gaggtgacgc
    14641 aaaatgcgac acgactgagg caaattaccg cagttcctgt caccgccaga tcggcctgta
    14701 aaaataaagt catataaacc atgcagttaa aaaatggcac gccttttgat tagggaagac
    14761 aggactaaag caaaggagtt aatcgtgaaa aaaaatgcag tggtgattca ccctcaggat
    14821 tgcgtcgcga cggctattac ggcgctcaag gccggcgaaa ccgccacaat gttcattggc
    14881 gaacgcgaga taagcgttgt gttacatcag gatgtgccat ttggccacaa attcgccatc
    14941 tgcgatgtgc cttttcatgg cgaagtttat aaatatggcg aatccattgg ccgcgccact
    15001 caggaaataa aaagtggcga ctatgtgcac gtccacaatg tggaaagcga acgcggacgt
    15061 ggtgactgga aataatataa aacaagggaa aatgattatg agcaatgaga cttttttggg
    15121 tttccgacgc cctgacggcc gttttggcat ccgtaattat gtactgattt tacctaccag
    15181 cgtttgtgcg aataaagttg cccaggatat tgcccggcag gtaaaaggtg cgacatgggt
    15241 gaataacgat tttggctgct gccaggtggc aggcgatgcg cgtctgacgg aaaagacatt
    15301 gattaatgtg gcgaataatc ccaacgtcgg cgctattgtg gttgtgggct taggctgtga
    15361 aggcgcggag ccgctgcgca tcgcagaaga gattaccgca tttggcaaac cgacctcctg
    15421 cattaccatt caggaagagg gcggcacgct taaatgtcag gccaggggga tttcgctggc
    15481 ccgcgactat gcgcaacaac tctccatgca aaaaccgcag caagcaccgg ttagcgagct
    15541 gctgctggcg atggagtgcg gcgggtcaga tacgacatcg gggctggcgt ctaacccttc
    15601 ctgcggggtc gcctcggata agctgatacg ctgcggcgga agctcaattc tttctgaaac
    15661 gacggaattt attggcgccg agcatgtgat ggcgaaacgc gcggtgacgc cggaggttgg
    15721 tcaacagctc attgatttag tggtcggctg tgaggcgcga gcaaaagcgc tgggcgagga
    15781 tattcgcggg ggacagccga cgccgggcag tattaaaggc gggctgacta ccattgaaga
    15841 aaaatcgtta ggttgtatgc ataaagcggg tcatgcgccg ctacagggcg tactggaata
    15901 tgccgatagt ccaacgcatc cgggcctgtg gattatggat accccagggc aggatattga
    15961 atctatttcc ggcatggtgg cgggtggagc gcagatcgtt atttttacta ccggtcgcgg
    16021 aacgcctgcc ggtaacccaa tagcgccggt aataaaaatt acgggtaata aagcaacgtg
    16081 ggaaatgatg caggacaata ttgatattga tgtgtccgcc attatgtctg gcgaggcttc
    16141 tattacgcaa atgggcgagg aaatttatca ggaaatttta cgcgtcgcga atgggaaaac
    16201 gactaaatca gaagatttag gtcataacga attctctatt tataagatcg cgccgacgtt
    16261 ctgataccaa atcgggcagc acaagctgtc cggttatctc ctgggaataa gctatgaaaa
    16321 ttaaaaaaac actggaacgt tttcctggtg gtatgatggt tgtaccgctg atcatcggcg
    16381 ccttgtttaa aacttttgcg ccggaggcgc tggaaatagg cggttttgtc atctctattt
    16441 cgcatggcgc aatggcgatt ttaggcatgt ttttagtctg tatgggcgcg gatatccagt
    16501 ttaaagccgc gccgaaagcg ttgaaaaaag gcgctgcgat cacctttgcg aaatttgcca
    16561 gcggcgtgat tattggcatt ctggtcggga aattttgcgg cccggatggg ttattaggtc
    16621 tgtcggcttt agcgattatt tcggcgatga ccaactcgaa cagtgggtta tatgccgcgt
    16681 tggtggggga gtacggcgat gaaaccgacg gcggcgcgat tgcggtaata tcgttgaacg
    16741 atggtccctt tttcaccatg ctggcgttag gatcggcagg catggtgtcg atacccttta
    16801 tgaatctggt ggcggttatt attcccatta tcattggcat gattttgggc aatctggatg
    16861 aggacatgcg caagtttctt aaacagggca gcgtggtaac gattcccttt tttgcctttg
    16921 ggttaggata cagtattgat ttcgcaagac ttatcacggc aggttcttca ggcattttac
    16981 tgggactcat gacggtggcg attggcggat tttttaatat tttcgccgat cgtgtgacgg
    17041 gaggcagcgg cgtggcaggc gcggcggtat ccaccacctc tggcaacgcc gtcgcgacgc
    17101 cagcggcaat cgcgctgctc gatccgcatt ttaccgacct ggcgtcgacg gcggcggcgc
    17161 aggtggcggc ctcgacgatt attaccgctc tgtgcgcccc cttcctgacc gtatggataa
    17221 aaaaacgcta cgatcgtaaa ctgaacccag ccgccgcagg cggttagcgt ttcggcggaa
    17281 aataaatcac gacgggcggt ctcgcccgtt tataaaccaa caggatggtg agtgatgaat
    17341 aagacgaaag atatagccgc atctcctctc tgttttgtct ctccttatcc gcaactggca
    17401 aaggctgccg aggcgctggt cgcgcagttg gattacgccg tcactattca tcaaacgacg
    17461 cttaatcgta tcctggatga gctaccttta ttagagtccc gtgggcacca ggtactgatt
    17521 agtcgtggcg gctgtgcgga aatattaaaa aagcacagta aattaccggt agtcgaaatt
    17581 aaaatgtccg gctacgacat tcttgatgcg cttatccctt ttaaaggaca aaaaggcact
    17641 gtcggtattg tcggcttttc cagtgtgatc aaaggatgcg cgcgcgtagc ggaacagtta
    17701 aatattaact ataaaatttt taccttacag ggaaatgata aagaaacgat ttcttgcctg
    17761 aagcggcaat tagcgtccac gccattagat tgcattgttg gcgataccgt ttgtcaggat
    17821 tatttttcac cgctgggctc gcaattccgt ttacttgatt ccagccccgc ctcaataacc
    17881 gaagctctgg aagaagcccg ctcattatat ctggcttttc gcagccaatt actggagcgc
    17941 catcatctgc agctgattct cgatcagttt gataaagctg ttatcacgct tgatgatacc
    18001 ggcgcgttac tgcattacaa taaatatgcg agccaacttt ttaaaattaa cgcctccggt
    18061 gaaatttatg acgcatcttt cctgaaacag gtattgcacc aggagcggca tacattacgt
    18121 gagggaaaaa ccgtcagcgc gaaagtcgtc gatacaccgc aaggcgcgat ggtagttaat
    18181 ctgtatccgg tatttgcggc cagacagtta agccgggtgg tgttgacgat gcaaaccgtc
    18241 tccagtttac agggggcgga acatcatgtt cgccgccagg aactgtctcg ccgcggcttg
    18301 agcgcccgct atcatttcga cgatctgctt accgaaaacc cggaaatgct gcgtcgtctg
    18361 gcgatcatta aaaattatgc cggtacggac gcgactatct taattaatgg cgaaagcggg
    18421 acgggaaaag aggtgctggc gcaaagtatt cataatgcca gccaacgcgt caacggcctg
    18481 tttgtcgcca ttaactgcgg cgcgatggcc actcagattc tggagagcga actctttggc
    18541 tatgtcgccg gcgcatttac cggcgcgtcg ccgaaaggca aaataggcct gtttgaatta
    18601 gcgcaccacg gtaccatttt tctggatgag attagcgaac tggataaacc gctacagacg
    18661 cgcttattac gggtattgca ggagcggcag attatgcggc tgggctcaga ccagatgata
    18721 cctgttgata ttcgcgtgat tgcggcgacc aatcagacgt taacgaagct cattgcggat
    18781 gggacatttc gcgaagatct ttattatcgg cttaacgtat taaaagtaac cactatcccg
    18841 ctacgcaaac gtccggagga tatcaaagcc atcggcctgt cgctgcttac tagtttcagc
    18901 cagcattata aacgcccggc actaacgtta accccggcgc tgtggcagga gcttcagcgc
    18961 ttcgcctggc ccggaaacgt caggcagtta agcaatatta tcgaacggct ggtgctctct
    19021 attgatcact ccccggcaac tctggatgag ggccgcctct tgctggacga tttggaagag
    19081 gggagccgac gcgagccaag tacctgccac gactgccaga tgctggctgg cgattataaa
    19141 acgattcgcc tgcgtatttt gagaaaatta ttagaggcgg aaagggataa taaatcgtta
    19201 gtggcgaaac ggttaaatgt cgatcgtacc tcgctgacgc gctggatacg cgagtcggcc
    19261 tgacaagaat ttacagactc tgtgggcagc cttgcaaagc gtaacgcaaa taacgtctat
    19321 tattataggc agttaacgat ccaagaggtg aagtgatgaa caaggttgct caatattatc
    19381 gtgaactggt ggcctcatta agcgagcgtt tacgcaatgg cgagcgcgac attgatgcgc
    19441 tggtggagca ggcgcgccag cgcgtgatgc aaacagggga gttaacgcga accgaggtgg
    19501 acgaactgac gcgcgctgtc agacgcgatc tggaagagtt cgccatgagc tacgaagaga
    19561 gccaggaaga tagcgtcttc ttgcgggtga ttaaagagag tctctggcag gaactggcgg
    19621 atattaccga caaaacccag ctggaatggc gtgaagtctt ccaggatttg aatcaccacg
    19681 gcgtgtatca cagtggcgaa gtggtggggt tggggaatct ggtgtgcgag aaatgccact
    19741 atcatctggc ggtttacacg ccggatgtgc tgccgctctg cccgaagtgt gggcacgatc
    19801 agttccagcg caggccgttt gagccgtaag gttcattatc gtgagcggac ggttgccgtc
    19861 cgccatgtta agagtgtagt tgggcttcca gccggtaata gccatcggca aagagtgaaa
    19921 acagcggcgt cagggcggta aatgcttcgt tcaacccgac tcctggctga ttccactcgg
    19981 caagtgagga taaaaactgc gcggcgcctt catcatcatt gctaaaaccg gcataaacaa
    20041 attctgcgca ggttgggcac caggcttcag tgtaaaaacg aatcagcggc gagccatgcc
    20101 aggagagcat atgaataccg gcgtcagagt cgggatcgtg gataatgcag ggacgaagca
    20161 atgcttttcc gttacgtact gaaaacgtta tatgggctac gtcgtgctgt agcaggctga
    20221 tttcaggtct attgttacgc caaaacatcg ctgttcatcc ctggattctt ctttgcgctt
    20281 tatgcgtagt attgcagccg ttccgccagc aaatcgacaa atccctgacg gtctacatcg
    20341 accatcaccg tcgcattcgg cttattcccc gtcaggaaat aataatccac caccgtcatc
    20401 ccctgggtat atttcccctg agtttccacg ccaacccaac gctcaacggt ggtgaaaatc
    20461 tcaggtttca gcagccaggc gatagtgcaa gggtcgtgca gcggcgcgcc gacaaatccc
    20521 catttttcgt ctttgtggta ttcaaagaag aagtcgagta gttcagccac gatcgtcgaa
    20581 attggattgc cgatgtcgcg gaaacgctcg atatcggcgg cgtgaatctg cgccttatgg
    20641 gtgacgtcca gcccggccat caccaccgga atgcctgact ggaagacaat ttctgccgct
    20701 tccggatcga cgtaaatatt aaattccgca gcgggcgtcc agttacccag cgccatcgcg
    20761 ccgcccatga tcacaatgcg ggcgattttc gtatgcagtt ccggatggct attcagcagc
    20821 agcgccacgt tggtctgtgg gccagtggag acgatggtga ccggctgtgc gctctcgcgc
    20881 agtgtttttg ccatcagctc aacggcagtg ccgctttgcg gggcgaatga cggctcgggc
    20941 agcgccgggc cgtcaagacc gctttcgccg tgaacgttat cagcgataat cagttcgcgc
    21001 atgagcggtt tcaccgcgcc gcccgccaca ggaatatccg ggcgtttgag cagtgtcagc
    21061 atccgcagca cgttgcgcag cgtcttctcc ggcgtctggt tgccggcgga agaggtgatc
    21121 gctttcactt ccagttcagg ggaggcgagg gcgagaacga gggcgatcgc gtcatcatga
    21181 cccggatcgc aatcaataat aatgggcagt gccattgtgg ctccttgtaa gcggtacttt
    21241 gtgacaaggt taacgcccgg ctggatacgt ttcgagaagc gaagaagtaa agcgtgaggt
    21301 agcgcgcact ctgacgtgcg cgccgggaag attagtgcag gattttcgca aggaagtcct
    21361 ttgcgcgatc ggaactgggg ttagcgaaga actcctcttt tggcgaatct tcgacgattt
    21421 taccttcatc cataaagatc acccggttag ccactttacg ggcaaagccc atttcgtgcg
    21481 tcaccaccat catggtcatc ccttcgttcg ccagctcgac catcacgtcc agtacctcgt
    21541 tgatcatttc cggatcgagc gcggaagtcg gttcatcgaa taacatggca atggggtcca
    21601 tacatagcgc gcgggcgatc gccacgcgct gctgctgacc gccggaaagc tgcgccggga
    21661 acttgttggc atgcgcagac aggccaacgc gctccagcag cttcaggcct ttatcgcggg
    21721 cggcggcctt atcgcgtttc agcactttca cctgcgccag cgtcaggttt tcgatgatcg
    21781 acaggtgggg aaacagctcg aagtgctgga ataccatgcc cacgcgggaa cgcagtttcg
    21841 ccagatcggt ttttttgtcg ttcacaataa tgccgttaac ggtaatttcg cctttttgca
    21901 ccggttccag accgttgacg gtcttaatta gcgtggattt accggaaccc gatggcccgc
    21961 agactaccac cacctcacct tttttcactt ctgtcgaaca atcggtcagc acctgaaagt
    22021 gaccatacca ttttgaaaca tttttcaggg taatcattaa actgtccttt tcttcaaata
    22081 gctgaccagc aacgacgcgc tcaggctgat aacaaaataa acggcgccgg cgaacagaat
    22141 catttcgacc tgagtaccgt cacgctcgcc gatagtcgac gcggtgcgga agaagtccgc
    22201 caggctgagt acataaacta aagaggtgtc ctgaaatagc acgatgccct gcgtaagcaa
    22261 cagcggcacc attgcccgaa acgcctgcgg cagaataatg agcttcatcg actgccagtg
    22321 ggtcatcccc agcgccagcg cggcgctgga ctgcccgcgg gaaatgcttt gaataccggc
    22381 gcgaataatc tcggaatagt aggccgcttc aaacatggag aatgccacca tcgcggagat
    22441 caggcggata tcggttttcg gcgatagtcc cagcacgttt tgcagaaagc cgggtacaat
    22501 cagatagaac cacagcaaga ccatgaccaa cgggatggaa cggaaaacgt taacatacgc
    22561 tttagcaaac caggcgatag gagcaaagct tgagaggcgc atgacggcca gaatggttcc
    22621 ccagactatc cccacgacaa cggcggtgac ggtgatcttc agcgtgatga ccaacccggc
    22681 cagcaggtaa ggcagtgagg ggataatcga actccagtca aattcgtaca ttatttgctc
    22741 cccacgttgc ccggcaggcg gactttgcgt tcaaccaggc tcatgaccag catgataacg
    22801 gcgttaatca gcacataggc cagcgtaatg gcggtgaagg attcccaggc gtgcgccgag
    22861 taatccaaca gtttgcctgc ctgcgccgcc atatccacca ggccgatggt tgatgcaata
    22921 gccgagtttt tcaccaggtt catcatctct gacgtcattg gcggcacgat aacgcgatag
    22981 gcattcggca gcaggacata gcgataagcc tgcggcagcg ttagccccat cgccagcgcc
    23041 gcgttcttct gtccgcgagg cagagactga atcgcggcgc gcacctgttc gcaaacacgg
    23101 gcggcggtaa acagtcccag acagatcatt gaggagagga aaaactgaat attgggatcg
    23161 agttccgcct taaaccacat gccaagatct tccggcaaca gttcaggcac caccaggtac
    23221 caggtgaaga attgcacgat cagcggcacg ttgcggaaca gttctacgta caatgtgccc
    23281 agtccggaga ggaaacggtt gggaacggta cgtaaaatgc cgaaaataga tcctaccagg
    23341 aaagcgataa tccaggcggt aatcgaaagg gctacggtga cctgaaaacc actccatagc
    23401 cagccgagat aggtggtatt gccgaagggg gcttcctgta aaaaaatacc ccagttccag
    23461 tctattgaca tacatctact ccgaaaaaaa agggtagcag cgctaccctc gaagattgtt
    23521 gcccggcgat ctgcggtttc aggcccgatg gggaacgacc atcaggctta tagtctgtcc
    23581 gtgctgagcg acaatcgaga ggacaggagt cccgtcccat ttagttttag ttagttaagc
    23641 gctttatcat tcggtgcttt gaacagggct ttcatctcgt cagacaactc gaaattcatg
    23701 ttcaggtttt tcggtgggat cggattttta aaccacttat caaaccactt ttccgcttcg
    23761 ccggaggttt gcgcctgagc gatggtatcg tccatcagct ttttaaactc agggtcgttt
    23821 ttacgcagca tacagccgta ggcttcctgg gactgcggtt taccgacaat ctcccagtta
    23881 tccggtttct tggctttggc gcgctcgccg gccagcagcg cgtcatccat cataaaggcg
    23941 acggcgcgac cgctttccag ggtgcggaac gagtcaccgt ggtctttcgc gctaataata
    24001 cgcatcccca tcttttgctc ttcgttaagc ttatgcagca gaatttcaga ggtcgtcccg
    24061 gaggtgacga cgaccgcttt gcctttcaga tccgggaaat ctttaatatc gccgcctttt
    24121 ttagtcagca gtcgcgtccc gacgacgaaa atcgtatcgg agaaggcggc ctgtttctgg
    24181 cgctcaaggt tgttagtcgt tgaaccacat tcaaaatcga aggttccgtt ttgcaacagc
    24241 ggaatacggt tttgcgaggt gatcgggatc agcttcacct gcagatcggg cttgttaagt
    24301 ttctttttta ccacttccac aatggcgttg gagtagtcct gggaatagcc gaccactttc
    24361 tgctggttgt cgtaataaga aaagggcaca gaagattcgc gatgcccgac gacgatcacg
    24421 ccatttttag cgatcttgtc cagggtgcta ccagcggcag gcgcgccatc ttctgcgtgc
    24481 gcaaggcccg cagacagtcc catgaccagc attgctgtgg ttagcttacg taattgcata
    24541 tccaactcct ttatcatctg cgccgtcgac gcattgatag ctattgtgat gttgttattg
    24601 cctgcaactt gcgcgtgcag tgttatgtgt gtttgttaac atttagtgtg gcttgttgta
    24661 aatattttgc tgcgatattg tttatttttg cgaagtgcgc cgcaccgttc agaggcaaaa
    24721 atcgcagttt gcacaataat ggtgctaccg atgctgtgtt gtggtgcaac ctggttgcgc
    24781 cggtagggag tgtgcagcct cttgattata ttaagcaatt ggcgtgccag aatgagattt
    24841 tggtggcggt gagaggttgt aggcctgata agcgtagcgc catcaggcac ggtgcgatac
    24901 aactgccgga tggcggcgta acgccttatc cggcctacat tggatagtgc aatgttttat
    24961 ttgcggcgtt gacgcaggct catcaccagc gcgccaaagc cgaacagtac ggtaatcaac
    25021 cacaccgtcc agtcgccggt tcgtgcgtac ggcgtcaggc cggtggtcgg cgtgactttg
    25081 gtagttagca cctggcgtgt gaactgcggg atcatcgcct gaatttcgcc ctgcgggcca
    25141 atcaccgccg taataccgtt attagtactg cgcagcaacg gacgcgccag ctccagcgaa
    25201 cgcatccgcg ccatctggaa atgttgccac gggccaatgg acttaccaaa ccaggcgtcg
    25261 ttagaaatcg tcagcagata gtcggtgtcc gggcggaagt tatcccgcac ctgttcgcca
    25321 agaataattt cataacagat tgccgccgtc agcttatagt cgtgcgcatg taactgcggc
    25381 tggatataag ggccgcggct aaaggaggac atgggcagat cgaagaacgg cgccagcgga
    25441 cgcaggatag actccagcgg aacgaactcg ccaaagggta caaggtgatt tttattgtag
    25501 cgattgggcg agtcataact gtatggatta tccttgccca acgtaataat cgtattgtag
    25561 gtgtcgtatc gattctgttt attgagacgc gcatcgacaa taccggtgat cagcgtgcta
    25621 tttttttcgc gtaacatctc gtccagcgaa cgaaggaaag gctgctgatt gatttcgaga
    25681 tccggaatcg ccgactcagg ccagataata atctgtgatt tgcctaactc tgggcgagtt
    25741 tcgttgagat aaatgtttag cgtattcagt agctggtttt cgtcccactt cagcgactgc
    25801 ggaatatcgc cctgcaccag cgatacctgg gtcgctttgg taggttccag cgtaaaccac
    25861 tggatataac gtagcggaaa gggcaaagca aacagaatca cggcgacagc cagcggacgc
    25921 cagttccgcg tcgccagtgc cagcgctaac aggccgctga ccatcatcag caggaagttg
    25981 atcgcttcga cgcccattac cggcgccagg ccttttagcg ggccgtcgac ctgactatag
    26041 ccaaattgca gccaggggaa gccggtcagc acccagccgc gtaaaaattc ggtgatttgc
    26101 catattgcag gcgcggcgat agcgacgcgc agccagttgg tttttggcca caggcgcgac
    26161 aaaatcccgg caaacagtcc ggtatacagc gagagataag ctgcaagcag caccaccaga
    26221 aaaacgttaa ccgggcccgg catgccgcca aactgcgcga tactgacata aacccagtta
    26281 atcccgctgc cgaaaagtcc gagtccccag caatagccga tggcggcaga ctggagcggg
    26341 cggcgattaa acgttaaggc ctgcagcccg ataagcgaca ctatcgctgc gggccagacg
    26401 tcatacggag agaaagccag tgttccgcag gcgccgaata ataacgccag cagcaggcga
    26461 atacgctggc gttcaattaa cgaggcaaat gccattttta gtccactatt gctgttattc
    26521 gtccagtttt ggctggggcg agtcatccgg gatcctgaca tgcacctgaa taatacgacg
    26581 actatcggcc attgccactt tgaactggta accatcaatg tcaatggttt cgccgcgggc
    26641 cggtaaatgg ccgaacgcct gcatcaccag cccgccgatg gtatcgactt cttcatcgct
    26701 gaagtgggtg ccgaaagcgt cattgaagtc ttcaatcgac gccagcgcgc gaatcgtcca
    26761 ggtatggcgg ctaagctgac ggaagtcgat atcgtcttct tcgtcatact catcttcaat
    26821 ttcaccgaca atcagttcga ggatgtcttc gatagtcaca aggccggaaa cgccgccaaa
    26881 ctcatcgata acgatggcca tatggtagcg ctgggagcgg aattccttga gcatacggtc
    26941 aacccgtttg ctttccggta cgacaaccgc ggtacgtaac actttgtcca tgctgaaggc
    27001 ttcggcatcg ctgcgcataa acggcagcaa atctttggcc atcagaatcc cttcaatgtg
    27061 atctttatct tcgctgatca ccggaaaacg cgagtgggcg gactcgatga taacatcgag
    27121 acattcgtcc agcgtctggt tgcgtttcag ggtaatcatc tgggagcgcg ggatcataat
    27181 atcgcgaacg cgctggtcgg cgatgtccat tacgccttcg agcatatcgc gcgtatcttc
    27241 atcgataagc tcgttctgcc cggaatcacg gatcagcgcc agcaactcat cacggttttt
    27301 aggttcaccg tggaaaagct ggctgagtag cagggaaaaa aatccctttt tactgtttac
    27361 tgtgtcacta ctgtgtgaat tgtcgtcgct catggcgtcg tatgggttct catgttagtt
    27421 aatacaaagc tcgtcatgcg tatactcagc tgtgacggca tgttttgcct gatgacgcta
    27481 cgcttatcag gcctacaaaa ggcatgaatg taggccggat aaggcgcaag cgccgccatc
    27541 cggcaagcta ctattctgca atcttctcgg caatgtacgg atcctcatag cccatagcaa
    27601 gcataatctc cgtttcgaga gactccatct cttccgcttc gtcatcgtcg atatgatcgt
    27661 aacccagcaa atgcaggcta ccgtgtacga ccatgtgcgc ccagtgcgcc tccagtggct
    27721 tgctctgttc ctgcgcttcc tgctccacga cctgacggca aataatcaga tcgcccagta
    27781 gcggcatttc aatgccgggg ggcgcttcaa acgggaagga gagaacatta gtgggtttat
    27841 ctttcccgcg gtacgtcaaa ttaaggtcat ggctttcggc ctcatccacc agacggattg
    27901 tgacttccgc ctcttcctga aactgcggaa taacgccgtc cagccagcgt tgaaactgag
    27961 cttcatccgg caggcccgcg tggttttcac aggccaactg taaatcgagg atcacctggc
    28021 tcatttctgt tcctgctcct gggcttcacg cttacgctcc gccgccaacg ccgctttgcg
    28081 tttttgttcg gcctcttccc aggcttcata ggcgttcaca atgcgggcaa cgaccggatg
    28141 gcgcaccacg tcttcgctgt ggaagaagtt aaagctgatt tcatcgactt ccgccagcac
    28201 ttcaatggca tgacgcaagc cggatttggt gttgcgtggc aggtcaatct gcgtcacgtc
    28261 gccggtgatc accgctttcg agttaaagcc gatacgcgtc aggaacatct tcatctgttc
    28321 gatagtggtg ttctggcttt catccagaat gataaaggcg tcgtttaatg tgcgtccgcg
    28381 catataggcc agcggcgcga cttcaatcac attgcgctca atcagcttct cgactttttc
    28441 aaagccgagc atttcgaaca gcgcgtcata cagcggacgc aggtacgggt ccaccttctg
    28501 acttaaatcg cctggcagaa agccgagttt ttcgcccgct tccaccgccg gacgggtcag
    28561 tagaatacgg cgaatctcct ggcgctccag ggcgtctacc gcagcggcga ccgcaagata
    28621 agttttaccg gtacccgccg ggccgacgcc aaaggtaata tcatgatcga gaatattggc
    28681 gatgtactgc gcctggttcg gggtacgcgg tttaatcacg ccgcgcttgg ttttgatatt
    28741 aatagctttg ccatagtcag gcacgctttc cgcgctctgt tccagcaccc gcgcttcttt
    28801 gatcgccaga tgaatttgtt ccggttcgat atcctgagtc tggccgcgca tcggtgcggt
    28861 atcgacatac agacttcgca aaatatctgt cgccgcggtc acgcaaatcg gacgaccggt
    28921 cagtttaaag tgattgtcac ggcggttgat ttcaataccg agacgacgtt cgagctgttt
    28981 aatattgtca tcaaacggcc cgcaaaggct caacagacgg gcgttgtctg cgggctcaag
    29041 ggtaatttcg cgagtgtcta tattcaaact gttcctcttg tgtctgtatc gccggacgct
    29101 gaacatttac cggcatctaa ggaaattatt cacgccatag ggaaaaggcg caagcattgc
    29161 aatgaagatg gggatgaaga gagaaaattg caaggcccgt cgggcgacag gccatgacca
    29221 ggaagcccga caggcgtagc gccatcgggc attattgcct ttcctgcagg attaaggctg
    29281 gtagaatcct acgcccagct cattttcttt acgggtacgg gcaatgacgg actccggcgt
    29341 ttcggcgacg cgcagaccca tttcatcttc ggtacgcacc acttttccgc gcagggagtt
    29401 cggatagacg tcagtaattt ccacatcgac aaacttacca atcatctccg gcgtgccttc
    29461 aaagttcacc acccgattgt tttcggtacg gccagacagt tccataatgt ttttacgcga
    29521 cgtgccttcc accagaatgc gctgtgtcgt gccgagcata cggcggctcc atgccatcgc
    29581 ctgctgattg atacgctctt gcagaatata cagacgctgc tttttctctt cttccggtac
    29641 gtcatcaacc atatcggcag ccggcgttcc cggacgcgca gagaagataa agctgtagct
    29701 catatcaaag ttgacgtcgg cgataagctt catggttttt tcgaaatcat cggtagtttc
    29761 gcctgggaaa ccgacgataa agtcagagct tatctgaatg tccggccgcg ccgcgcgcag
    29821 tttacggatg attgctttat attccagcgc agtgtgggtg cgccccatca gattcaacac
    29881 gcgatcggaa ccgctctgta ccggcagatg caggaaactg accagctccg gcgtatcgcg
    29941 gtacacctcg ataatatcgt cggtgaactc aatcggatgg ctggtggtaa agcgaatacg
    30001 gtcaatgccg tcgatggcgg caaccagacg cagcagatcg gcaaaggtgc cggtggtgcc
    30061 gtcgtagttt tctccgcgcc aggcgttaac gttctggccc agcaggttga cctcacgcac
    30121 gccctgcgcc gctaactggg cgatttcgaa caggatatcg tctgagggac ggctgacttc
    30181 ttcaccgcgg gtatacggta ccacgcagta agtacaatat ttattgcagc cttccatgat
    30241 agaaacgaaa gcggtcgggc cttcggcgcg cggctccggc aaacgatcga acttctcgat
    30301 ttccgggaag ctgatatcga ccaccgggct gcggtcgcca cgcacggagt taatcatctc
    30361 cggcaggcgg tgtaaggttt gcgggccaaa aataatgtcg acgtaatggg cgcgttgacg
    30421 aatgtgctcg ccttcctggg aagccacaca gccgccgacg ccgataatca gatcgggatt
    30481 tttctctttt aacagtctcc agcgacctaa ttgatggaag actttttcct gagccttctc
    30541 gcggattgag caggtattca acagcagcac atccgcctct tccgccacgt cggtcagttg
    30601 atagccgtgg gtggcgtcca gcagatcggc catcttcgat gaatcgtact cgttcatctg
    30661 acagccccag gttttaatat ggagtttttt agtcatcgac ttgctcttgc gaaatagtgg
    30721 ctgaaaagca gggcgcatag tgtaatgctt tggcgcggtt gtgaccagta tgactgacgt
    30781 cagccctaat gggtaaaaaa tcctgtaaac ttgtctaaaa cgtaacagga tgaatgacca
    30841 tgacaaatca accaacggaa attgccattg tcggcggggg aatggtcggc ggcgcgctgg
    30901 cgctgggtct ggcgcagcaa gggtttacgg tgatggtaat agaacatgcc gcgcctgcgc
    30961 cgtttgtggc tgacagccag cctgacgtgc ggatttcggc cattagcgcg gcatccgtgg
    31021 cgctgctcaa ggggctgggc gtttgggagg cggtgcaggg gatgcgtagc catccttatc
    31081 ggcgactgga gacctgggag tgggaaaacg cccatgtggt gttcgacgcc gctgaactca
    31141 agctgccgct gttaggctat atggtagaga acaacgtcct gcaacaggcg ctgtggcagg
    31201 cgctggaagc gcaccccggc gtgacgctgc gcgttccggc ttcactggcg gcattgcacc
    31261 gccgccacga tggttatgcg ctggaactgg ccgacggcga atgggtaacg ccgaagttag
    31321 tgattggcgc cgacggcgcg aattcgcagg ttcggcaaat ggcgggaatt ggcattcatg
    31381 cctggcaata tgcgcagtcg tgtatgctta tcaccgtcaa gtgtgaaaat gcgccaggcg
    31441 acagcacctg gcagcagttt acgccaacgg ggccgcgcgc ctttttgccg ctgttcgacg
    31501 attgggcgtc gctggtgtgg tatgacgctc cggcacgtat tcgccagcta cagagtttat
    31561 cgatgacgca attgcaggtg gaaattaacc agcactttcc ggcgcgtctg ggggcggtga
    31621 tgcctgtcgc ggcgggcgcg tttccgctaa cccgtcgtca cgcgttgcag tatgcgcaac
    31681 cggggctggc gctggtaggc gacgcggcgc ataccattca tccgctggcc gggcagggcg
    31741 tcaacctggg gtatcgggat gttgatgcgt tgattgatgt gctggcgagt gcccgtagct
    31801 atggcgagtc ctgggccagc cattcggtgt tgaaacgcta tcagacgcgg cgcatggcag
    31861 ataattttat gatgcaaagt ggaatggatc tgttttatgc cgggttcagc aatgaactgc
    31921 cgccactgcg tattttacgc aatatggggc taatggcggc gcagcgcgca ggcgtgctaa
    31981 aacgtcaggc gctgaagtat gcgttggggt tgtagtttgt gttatgccgg gtggcggcta
    32041 taccttaccc ggcctgtatt cgcccgtagg cctgataagc gtagcgccat caggctgtcc
    32101 gaattgccag aaaagcaaaa agctcgccga agcgagcttt ttaaaagtgg ctggggtacg
    32161 aggattcgaa cctcggaatg ccggaatcag aatccggtgc cttaccgctt ggcgataccc
    32221 caacaaatta ttttcgaacc ggtcgaatac ctcgacgcgt tctgaatatg gtggctacga
    32281 cgggattcga acctgtgacc ccatcattat gagtgatgtg ctctaaccaa ctgagctacg
    32341 tagccagatg atttcttcga tggctggggt acctggattc gaaccaggga atgccggtat
    32401 caaaaaccgg tgccttaccg cttggcgata ccccaatacc gtcgcggtga accgcaaact
    32461 cgaagaaata tggctggggt acctggattc gaaccaggga atgccggtat caaaaaccgg
    32521 tgccttaccg cttggcgata ccccatccgt acaacgctta tcggtgaatg gtgcgggagg
    32581 cgagacttga actcgcacac cttgcggcgc cagaacctaa atctggtgcg tctaccaatt
    32641 tcgccactcc cgcaaaaaag atggtggcta cgacgggatt cgaacctgtg accccatcat
    32701 tatgagtgat gtgctctaac caactgagct acgtagccat cttttttcgc gttaccttat
    32761 cggcgttgcg gggcgcatta tgcgtattga gccttgaagc gtcaacctct ttttcatcga
    32821 aaaacgtcgg aaagtgtctg tttggttagg ttgcgaacag cgtggcgcaa tattcggcaa
    32881 ttattggtta ttaatcgttt ttccgaaagt gggttgctat aaaaaaagag cccctagggg
    32941 ctctttcgtc atcgttaatt tactggtacg ccgactgatg cacgccgacc gcgcggcctg
    33001 acgggtcatc catcgttttg aatgcttcat cccactcaat ggctttggcg gaagaacagg
    33061 ccacggacgg gccgccgggt acgcattccg cggcgctcgg caccgggaac aattcttcaa
    33121 aaatttcccg gtacaagtac gcctctttag acgacggcgt gttgtatgga aagcggaagc
    33181 gggctgtttc cagttgttga tcggaaatct gtttcgccgc cacctctttc agcgtatcaa
    33241 tccagctgta gcctacgccg tcagagaact gctctttctg acgccacgcc acgcttgctg
    33301 gcagataaga ctcgaagcac tcgcgcagca cgtgtttttc catcttgccg ttgccgcaca
    33361 ttttatcctg tgggttgata cgcatcgcca cgtcgaggaa ttttttatcc aggaacggta
    33421 cgcgcgcttc cacgccccag gcggacatcg ctttgttggc gcgggtgcag tcatacatat
    33481 gcagcgcctg tagcttacgg accgtctctt catgtaactc tttggcgttc ggcgctttat
    33541 ggaagtacag gtagccgcca aacacctcat cagaaccttc gccggagagc accattttga
    33601 tgcccatcgc tttgatctta cgcgacatca gatacattgg cgttgaggcg cggatagtgg
    33661 ttacgtcata ggtttcaatg tggtaaatca cgtcgcgaat cgcatccaga ccctcctgga
    33721 cggtgaagtg aatttcatga tgcacggtgc cgaggtggtt agccacttcc tgggccgcct
    33781 tcaggtcagg cgaaccttcc agacctaccg caaaagagtg caactgtggc caccaggctt
    33841 cggagcgctc ctgatcttcg acgcgacggg cggcgaattt tttggtgatt gccgagataa
    33901 ccgacgagtc caggccgccg gagagcagta cgccgtaggg cacgtcggac atcaggtggc
    33961 ttttcacgga ttcttccagc gcctgacgca gcgcgttttt gtcggtgacg ttatctttta
    34021 ccgcatcgta atcgaaccag tcgcgctgat agtactgacg aatttcgccg tctttgctcc
    34081 acaggtagct gcccgccggg aactctttaa tggtgcggca gaccggagtc agcgctttca
    34141 tttctgacgc tacgtagaag ttgccgaatt cgtcatagcc catgtagagc ggaataatac
    34201 cgatatggtc acgaccaatc agataagcgt ctttttcgct gtcatacagg gcgaaggcga
    34261 acatcccctg taaatcgtca aggaaatccg gccctttttc ctgatatagc gcgagaataa
    34321 cttcgcagtc ggagccagtc tggaacgcgt aacgatcgcc atactccgcg cgtaacgtct
    34381 gatggttata aatttcaccg ttcaccgcca gcacgtgagt tttcttagcg ttatacaggg
    34441 gctgggcgcc ggcgttaaca tcaacaatcg acaagcgttc atgtgcgaga atcgcgttat
    34501 cgcaagcgta gatgccggac cagtccgggc cgcgatggcg catcaggcgt gacaattcaa
    34561 gggctttttt acgcagttcc gctgcatctg ttttgatatc gaatacgccg aaaatagaac
    34621 acatagcctt ctccgttaat ctgttgcgtc gtactttttg tgtttgcttg actaaaaaat
    34681 gccgcaaagg cgtggaaggc gcaaggggat tacggtctga aaaatgaaaa acgcaatcgt
    34741 cattgttgat tagtgaaaaa tgattacgta ttgcgcgaat ttattgatga atcttcagtt
    34801 ttatagtggt ttaattgaat tatgtttttc ctgatgacgt ttcgcttatc aggcctacaa
    34861 tgttgttcga accgtaggcc tgaaagcggc gcgtcatcag gcaggggaca ggtttagata
    34921 acgtctatct cggcgacgga agggtaaatc cagcttgggc ggaacggcat actgtcaata
    34981 tcattgattg ttgatacgcc tgaaagcacc agaatggtct ccagaccggc ctggaacccc
    35041 gccagaatgt cggtgcgcag gttgtcgccg acgataacgg tctcttccga gtgcgcctgc
    35101 attttgttta acgccgcgcg gatgatccac gggctgggtt tgccgacata aaacggcttc
    35161 cggccggaaa ttttttcaat gcctgcgcac agcgcgccgc aggccggata aaagccgcga
    35221 ccgtgggtat ccgggttggt ggcgataaag cgcgcgccat tagcgacgaa aaatgctgct
    35281 ttatgcatca tgtcccagtt gtaggagcgg gtctctccaa cgatgacaaa atcagggttt
    35341 acatcggtaa tggtaaaacc cgctttatag agctcgtgaa taagcgcgcc ttcgcccacg
    35401 acatacgctt ttttaccttc ctgacggcgc agaaaatcgg ctgtcgccat tgctgacgta
    35461 taaaacacgc tgtccggcac gttaacgcca gcggtagcaa aacggttcgc cagatcctgg
    35521 ccggtttgcg acgggtaatt ggtcagcagc accagcggca gacctttttc cagaatcccc
    35581 gtcagaaatt ccgccgcacc gggtacggct acgttgtcgt gcatcagcac gccgtcgata
    35641 tcgcagatta cattcttgat ggtcatgaac tacccaggga atttgtgaat aatccgatac
    35701 tataagagcg catcagcttt ccagcaaacg ttgcagcaat gttccgttga gcatggcgcg
    35761 tttaactaag gcaaatgcgc cgatagcaga acggtgatcc agcgtggagc gtaccaccgg
    35821 caaatttttg cgaaaggcct ttaacgcctg cgtattgata cagctttcga tagcgggcaa
    35881 caggacttta tcggcttcaa tgatctcgcc ggcaatgacg attttttgcg gattaaacag
    35941 gttgatagca atggcgatcg ttttgcccaa atggcggcca acatgctcaa tgacttccga
    36001 ggccaggctg tcgccccggt ttgccgcctt acagatggtt ttaatcgtgc agtcgtcaag
    36061 cggaacacgg ctttgatacc cttgtttaag caaattcagc acccgttgtt caatcgccgc
    36121 attggcggca atggtttcca gacagccgaa attaccgcag tggcagcgct cgcccaacgg
    36181 ctccacctga atatgcccaa tttcgccgac gttgccgtta cggccaatga agatgcgtcc
    36241 gttggagata atcccggcac ctgtaccacg atggacgcgc accagaatcg agtcctcgca
    36301 atcctgactg gcgccgaagt agtgttccgc cagtgccagg ctacgaatat cgtgacccac
    36361 gaaacaggta acgtgaaacc gtttttccag cgcttcgacc agtccccagt tttcaacctg
    36421 aatgtgcggc atgtaacgaa tcacgccgct ttccggatcg acaagccctg gcaggatcac
    36481 cgagatagcg atcaattcac gaattttacg ctgacaacta tcaataaaga cggcgatagt
    36541 gttgagcagc gcatgttcca gcgtctcctg ggtgcgctcc ggcagcggat aatgctcctc
    36601 agcgaccact ttactgctca gatcgtagag cgttaaagtg gtgtcatgac gccccaggcg
    36661 aacgccaatg gcgtggaagt tacgggtttc cgtgacgata gagatagcgc ggcggcctcc
    36721 ggtagaggcc tgctgatcga cttctttgat cagcccgcgt tcaatgagtt gacgcgtaat
    36781 tttcgttacg ctggcgggag caagctggct ttgctcggca atttgtatgc gcgagatagg
    36841 accatgctgg tcaatcaggc ggtaaacggc cgcgctgtta agctgtttta cgagatcaac
    36901 gttacctatc tgagcttgtc cgcctggtgt catattctca cttactcaag tcaacgacct
    36961 cgtcaccatt aacgatggtc ttgataattt taaaatcgtg ggtgaacgcg gtcaggttgg
    37021 cgactttact cggcgcaatg ctaccgagat gcttatcaac gccgatagcg cgtgccggat
    37081 agagcgttgc catgcgcagc acttcatcca gcgcgatgcc gcaatgcgcg accaggttgc
    37141 gtacgccttc aatcatggtt aaggacgaac cgctcaacgt accgttttca tccacacaca
    37201 gtccattgcg gtagtatatt gttttacctg cgaaaatgaa ctgctcaata ttggcccccg
    37261 ccggtgcggt ggcgtctgtc accagacaaa gtttgtcgcc tttcaggcgt ttggcattgc
    37321 gaatgttggc gtagtcgaca tgcagaccat cggcgataac gccgcaataa atatccgctt
    37381 cgtccagaac agcgccagca aggcccggct cacgccctgt aatgtacggc atcgcgttaa
    37441 acaggtgagt cgcaaaggta atcccggcgc ggaagcccgc ttttgcctct tttaacgtcg
    37501 cgttggagtg acctgcggaa accacaatgc ccgcattcgc cagtttagcg attacgtcag
    37561 caggcaccat ttccggcgcg agagtgactt tggtgatgac gtcggcatta tcgcataaga
    37621 aatcgaccag cgcagcgtct ggtttacgca cgaaatcagg attatgggtg ccttttttta
    37681 ccagattaag ccaggggcct tccaggtgga gacccagcgc ctggtgcgga tgtttttcca
    37741 gatactcgcg catgacgcga ataccctgtt tcatcaattc gtcgctggta gtgataagcg
    37801 ttggcagaaa gttagtacag cccgattttt cattggcttt ctgcataatt tccagcgttt
    37861 caacgctgac ggcttctgcg gtatcgttaa actgcactcc gccgcagccg tttagctgca
    37921 catcaataaa accgggggag agaatggccc cattcaatga gcgttgttct attcccggcg
    37981 gcagctcggc catcggacaa acgcggtcaa tcaggccatt agcgacaaca agcgcatggt
    38041 catcaagaat ttcgtgaccg gtaaagatcc ggccctgggt taaagcatac attctgaccc
    38101 ccgatatcaa aaatttaccg ccccgcattg actggcgggg cggagacaac attacagacc
    38161 tttaatattt tctgcttcta attcattgaa atatttcaat gttttaactt taagttccat
    38221 tgtggacggc tcatcgcata ccacaaccgc tttcggatgg agttgcaggc agctaatggt
    38281 ccacatgtgg ttgacgttgc cttcaaccgc cgcctgcagc gcctgggctt tctgatggcc
    38341 cagcaccaga atcatcactt cttccgcatc cagcagcgta cccacgccta ccgtcagcgc
    38401 gtatttcggc acctggttta cgtcgccgtc aaagaagcgg gagttcgcta cgcgagtatc
    38461 atgggttaac gttttgatac gggtacggga agccagggaa gacgccggtt cgttaaaggc
    38521 gatgtgaccg tcgttgccga cgccgcccat aaacagatgg attttaccgt aagaacgaat
    38581 tttttcttca tattgacggc attctgcatc gatatccggt gcgttaccgt tgagaagatt
    38641 gatgttttct gctggaatat caacgtgatc gaaaaagtta cgatgcataa agctgtggta
    38701 gctttccggg tgctctttcg gcaggccaac atattcgtcc atattaaagg tgaccacatg
    38761 cttaaagctg acctcgcccg ctttgtgcat ctcaaccagc gctttgtacg ccgttagcgg
    38821 cgtgccgccg gtaggcagtc caagaacaaa cggacgatcg gtggttggtt tgaacgcatt
    38881 aatacggtta acgatatggc gagcggccca tttgccaacc tgttctgcgg tactcagggg
    38941 gatcagtctc attcttcacc tcaataatca atgtcaaaat ttggcggatc gtattaagcg
    39001 taacctggat atccagggtt cgtgttcaat ccgtcctgat tttttgaatc ataaaataag
    39061 ttttccgtgt tagccagtgg atggtggggg tgattacgat atttagtgat tataatcaca
    39121 aaaaacaccc gtttaatttg cgaggcgaat taattttcca cacactctgc agaagatgat
    39181 ctcaccgttc gattacagaa catcacgttt ttaacgtttg cagcacaata aaaaacggct
    39241 tcaaagaagc catatcggcg tctcgtaggg ggaataagat gaatatttta ggttttttcc
    39301 agcggctggg tagggcgttg cagctcccta tcgtcgtgtt gccggtggca gcgttgttgc
    39361 tgcgattcgg ccaaccagat ttgctgaata tgccgtttat cgcgcaagcg ggcgggtcta
    39421 ttttcgataa cctggcgctg gttttcgcta tcggcgtggc ctccagttgg tctaaagata
    39481 gcgcaggcgc ggcagcactg gcgggagccg tgggttactt cgtcatgacc aaagcgatgg
    39541 tgacgattaa cccggaaatc aacatgggcg tgctggcggg gattattacc ggtctggtcg
    39601 gcggcgcggt ttataatcgc tggtctggta tcaaactgcc tgattttctc agtttcttcg
    39661 gtggaaaacg ttttgtgccg atcgcaacgg gctttttctg tctggtgctg gccgctattt
    39721 tcggttacgt ctggccgccg gtacagcatg gcatccatgc gggcggtgaa tggatcgttt
    39781 ccgcaggcgc gttgggttcc ggtatctttg gcttcatcaa ccgtctgctg atccccaccg
    39841 gtctgcatca ggtactgaac accatcgcct ggttccagat tggcgaattc accaatgccg
    39901 caggcactgt attccacggc gacatcaacc gcttctatgc tggcgacggc acggcgggga
    39961 tgtttatgtc cggcttcttc ccgatcatga tgtttggtct gccgggcgcc gctctggcga
    40021 tgtatttcgc cgcgccgaaa gaacgtcgtc cgatggtggg cggtatgctg ctgtctgtcg
    40081 cgatcaccgc gtttctgacc ggcgtaaccg agccgctgga attcctgttt atgttcctgg
    40141 cgccgctgct gtacctcctg cacgccattt tgactggtat cagcctgttc gtcgcgacgt
    40201 tgctgggtat ccatgcgggc ttctctttct cggcaggcgc gatcgactat gttctgatgt
    40261 ataacctgcc tgcggccagc aataacgtct ggatgttgct ggtgatgggc gttgtattct
    40321 ttatcatcta cttcctgctg ttcagcgcgg ttattcgtat gtttaacctg aaaacgccgg
    40381 gccgcgaaga taaagttgat gagatggtaa cggaagaagc caacagcaac accgaagaag
    40441 ggttaacgca actggcgacc agctatattg ctgcggttgg cggtacggac aacctgaaag
    40501 cggtcgatgc gtgtattacc cgtctgcgcc tgaccgtgaa cgactctgct cgcgtcaacg
    40561 atgcggcctg caaacgcctc ggcgcttccg gcgtggtgaa actgaacaaa cagaccattc
    40621 aggttattgt cggcgcgaaa gcggaatcga ttggcgatga aatgaagaaa gtggtggcgc
    40681 gggggccggt cgcggcagcg tctgctgatg cggctcacgt tgcgacacct gctccggcgg
    40741 ccaaacccca ggcggtgccg aatgcggtga ctatcgctga actggtctct ccgattaccg
    40801 gtgaggtagt ggcgctggat caggtaccgg atgaagcttt cgccagcaaa gcggtcggcg
    40861 acggcgtggc ggtgaaaccc accgataaaa ccgtggtttc tccggcggcg ggtactatcg
    40921 tgaaaatctt caacactaac cacgcgttct gtctggaaac cgaaaaaggc gcggagatcg
    40981 ttgtccatat gggtatcgat accgtcgcgc tgaacggtca gggcttcaag cgtctggtag
    41041 aagagggtgc ggaagtcacg gcgggtcagc cggttctgga actggatctg gacttcctga
    41101 atgccaatgc gcgttccaag ataagcccgg ttgtttgcag caacagcgat gacttcagcg
    41161 ctctggtcat caaagcggat ggtcacgtgg tagcgggtca aacgccgctg tacgagatca
    41221 agagcaaata atcgcttcct ggccggataa ggcgtaagac gccatccggc gatatcacag
    41281 gaaacataag cggcagaggg aaaccttcgc cgcttttttt taccgcaatt agccccaata
    41341 ttttctgcaa agccactttt taagtaacta aaggttgtca gtctgtccgg cttataagat
    41401 catatgccgt tatacgttgt ttacgctttg aggaatccac gatgagtgag gctgaagccc
    41461 gcccgactaa ctttattcgt cagattattg atgaagatct ggcgagtggt aaacatacca
    41521 ctgtccatac ccgttttccg ccggagccga atggctatct gcacatcggc cacgcgaaat
    41581 ctatctgcct gaactttggc atcgcgcaag attatcaggg ccagtgcaac ctgcgtttcg
    41641 atgacaccaa cccggtaaaa gaagatatcg agtacgttga ttcgatcaaa aacgacgtcg
    41701 agtggttagg ctttcactgg tctggcgata ttcgctactc ctccgattac tttgaccaac
    41761 tgcacgccta tgcggtcgag ctcatcaata aaggcctggc ctacgttgat gagctgacgc
    41821 cggagcagat ccgcgaatac cgtggtacgc tgaccgcgcc gggtaaaaac agcccgttcc
    41881 gcgatcgcag cgtggaagaa aacctcgcgc tatttgaaaa aatgcgtacc ggcggttttg
    41941 aagagggtaa agcctgtctg cgcgctaaaa tcgacatggc gtcgccgttt atcgtgatgc
    42001 gcgatccggt gctgtatcgc attaaattcg ccgagcatca tcagaccggc acgaagtggt
    42061 gcatctatcc gatgtacgac tttactcact gcatcagcga tgcgctggaa ggcattactc
    42121 attctctgtg tacgctggag ttccaggaca accgtcgtct gtacgactgg gtgctggaca
    42181 acatcaccat tccggttcac ccgcgccagt acgaattctc gcgcctgaat ctggaataca
    42241 ccgtgatgtc caagcgtaag ctgaacctgc tggtgaccga caaacacgtc gaaggttggg
    42301 atgatccgcg tatgccgact atttccggtc tgcgccgtcg cggctatacc gcggcttcta
    42361 ttcgtgagtt ctgcaaacgc atcggcgtca ccaagcagga caacactatt gagatggcgt
    42421 cgctggaatc ctgcattcgc gaagatctga acgaaaacgc gccgcgcgcg atggcggtaa
    42481 tcgatccggt aaaactggtt atcgaaaact acccgcaggg cgagagcgaa atggttacca
    42541 tgcctaacca tccgaataaa ccggagatgg gcagccgtga agtgccgttt agcggtgaga
    42601 tctggatcga tcgcgcggat ttccgcgaag aagcgaacaa acagtacaaa cgtctggtga
    42661 tgggcaaaga agtgcgtctg cgtaatgcct acgtcattaa agcggagcgc gtagagaagg
    42721 atgccgaagg gaatatcacc accatcttct gtacctatga tgctgatacg ctgagtaaag
    42781 atccggctga cgggcgtaaa gtgaaaggcg taatccactg ggttagcgta gcacatgcgc
    42841 tgccgattga aattcgtctc tacgaccgtc tgttcagcgt gccgaacccg ggcgccgcgg
    42901 aggacttcct gtctgttatc aaccccgaat cattagtgat taagcagggg tatggcgagc
    42961 cgtcgctgaa agcggcggta gcagggaaag ctttccagtt tgaacgtgaa ggttacttct
    43021 gccttgacag ccgctatgca acggccgata agctggtctt taaccgcacc gtgggcctgc
    43081 gtgatacctg ggcgaaagcg ggcgaataag cactgcgcca acaggcgaat gctgtaaaaa
    43141 taccttgtca acgccgcgtt ctgcggcgtt ttttctctgc atttctaagt cgattctctt
    43201 ttttgcgagg cgaattaatt attctctgaa aattattgat ctgataaatg attattaatc
    43261 taaatgttat aagcgtcagg tcaacaggag acaattattt tcatgcctat ggaaaacaag
    43321 tcaattttct ttctggcggt ctgcttcccc caccagcagt cgaatgtaac agaaagcaat
    43381 taaatatgtg cggttgctca tattattaca tactggttac agaaagagat tgataattcg
    43441 catcgcgaaa aatagtctat ttaacgtagt aaatgaggtt tctcagcgct actttttatt
    43501 tttatttttt cgctgttcgc ttttgtcggc agcaatttat acgtcaaaga ggattaactt
    43561 atgcgtacgt ttagtggcaa acgtagtacg ctggctctgg ctatcgccgg tatcacagca
    43621 atgtcggggt ggatcgttgt tccgcaggcg caagcctccg gctttttcga cgactccacg
    43681 ttaacgggcg gcatctatta ttggcagcgt gaacgcgatc gcaaagatgt gaccgacggc
    43741 gacaaatata aaactaacct ttctcatgcg acctggaacg ctaacctgga ttttcagtct
    43801 ggttacgctg cggatatgtt cggtctggat atcgcggcgt ttaccgcgat tgaaatggca
    43861 gaaaacggcg acagcggtca tccaaacgaa attgccttct cgaaaaagaa taaaggctac
    43921 gacgaagact attccggcga taagagcggt atcagtcttt ataaagccgc cgcgaaattt
    43981 aaatatggcc cggtctgggc gcgcgccggt tatattcagc ctaccggtca gacgctgtta
    44041 gcgccgcact ggagttttat gccgggtacc tatcagggtg cggaagccgg cgccagtttt
    44101 gactatggcg atgcgggcgc gttaagtttt tcctacatgt ggactaacga atataaagcg
    44161 ccgtggcata ccgaaatgga taagttttat caggcggata aaaaaaccaa tgtagactat
    44221 ctccactcca tcggcgcgaa gtacgacttc aaaaatgatc tggtgctgga agcggcgttt
    44281 ggtcagtccg aaggctatgt cgatcaatat ttcgcaaagg ccagctataa atttgattta
    44341 ggcggcaatc cgttcaccac cagttaccag ttctacggcg cgcgcgacaa agtagacgat
    44401 cgcagcgtga atgacattta cgacggtacg gcctggctgc aggcgttgac cttcggctac
    44461 aaagtcgcgg aagtggttga cctgcgtctg gagggcacct gggtgaaagc ggacggtcag
    44521 cagggctatt ttctgcaacg tatgacgcca acctacgcct cttcaaacgg tcgtctggat
    44581 atctggtggg ataaccgctc cgactttaac gctaacggtg aaaaggcggt tttcttcggc
    44641 gcgatgtatg acctgaaaaa ctggaatctg ccgggctggg ctgtgggcgc gtcttacgtt
    44701 tacgcctggg atgctaaacc ggcaacctgg caaagtaacc cggatgctta ctacgacaaa
    44761 aaccgcacta tcgaagagtc ctcatacagt ctggatgcgg tctataccct gcaggagggg
    44821 cgtgccaaag gcaccatgtt caaactgcac ttcaccgaat atgacaacca ctccaatatt
    44881 ccaagctggg gcggtggtta cggcaacatc ttccaggatg aacgtgacgt gaaatttatc
    44941 gttattgcgc cattcactat tttctgatgt cagatgcggc aggctgccgg tctgccgcgc
    45001 tgttgaggaa cgacctatga aaaaaatttt actcatcgcc agcatgaccg ccggtttgac
    45061 ggcctgcgcg tcatcacccg cgccggaaga agatagtcgg ctgaaagagg cgtacagcgc
    45121 ctgtatcaat accgcacagg gctcgcctga gaagatagag gcctgccaaa gcgtactgaa
    45181 tgtccttaaa aaagagcgca aacatcagca atttgctaac gaagaaagcg tgcgggtact
    45241 ggactatcag cagtgcattc aggcgacgcg cacgggtaac gatcaggcgg tcaaggctga
    45301 ctgcgataag gtctggcagg aaattcgcag tcataataac gtgcaataaa accctgcctt
    45361 gccacccacg ggcgaatgtt ttccgcctgt ggttttttca ggctttattt tctgccgcga
    45421 tatagccgcg actcagacgt acaaacagca tcgccgtcgc ggcaagtcca cataacgctg
    45481 cgcacatcag ccaccagccg ggcgagcttt tatcgccggt taactttacc agcgcggtag
    45541 agatggccgg cgtcaggccg ccaaaaattg ccgtcgccag gctaaaggcc agcgagaaac
    45601 caacggtacg cacatagact ggcatcactt cggttaacgc cgcgaccatt gcgccgttat
    45661 acatgccaaa aaagaaagag aaccacagca gtaccagcgt catgcgggta aagtcgggcg
    45721 cggcggtcag ccactgcatg acgggccagg tggtgatcag cgccagcaac gtaatgccca
    45781 ttaacacggc gcgacggcca atccggtcgg aaatcgcgcc gccaatgggt aaccagataa
    45841 aattggacac ccccactaac atggtgacga tcaaactgtc ccgcgcgctg agattaagca
    45901 cggttctgcc ataggtcggc gtataaacgg tgataaaata aaacgttgtg gtggtcatcg
    45961 ccaccagcag cgttccggcc gtaataatgc gccagttttt ggcgatagtt gcaaaaattt
    46021 ccctagtgtc ggggcgatgc ttgcgttgta aaaacgcttc tgtttcttgt aatgaacgac
    46081 gtaaaacaaa aatcagcgga atgatcatac agccgataaa gaacggaatt cgccagcccc
    46141 actccgatat cgcgtcgtgt cccagcgtga tattcaggct ataaccaatc aacgcggcga
    46201 caacgatcgc aacctgctga ctggcggatt gccagctggt ataaaaccct ttattgcctg
    46261 gcgttgcgat ttcggacaga tagaccgaga cgccgcctaa ctcaacgccc gcagaaaatc
    46321 cttgtaataa ccggcccaac aacaccaacg caggcgctgc caggccgatc gtctggtagc
    46381 cggggacgag ggcgatgagc aacgtaccgc agcccataat cgccagcgtc accatcagcc
    46441 ctttacgacg tccgattctg tcaatatagg cgccaagcac aatcgcgccg acggggcgca
    46501 ttaaaaaacc ggagccaaag acggcaaagg tcaacattaa tgaggcaaat tcgctttccg
    46561 ccggaaaaaa cgttctggcg atataggtgg cgtaaaatcc gaacaagaaa aaatcaaact
    46621 gttcaaggaa attgccgctt gtcacgcgca gtattgcgcc gaacgtgccg gcgcgcgatg
    46681 ttgcaggtgt gtgttgtgcc atagggtttg ctctccactg tctttattgt tttataggta
    46741 agatgttgcg ggtcagttgc ctgtatcccc cgcatgtttt ccgcgtcgct tctcaactgc
    46801 ccatttgagt aaggccgcgc agcggaaaaa tccgtgggcg aattttccgt agggaagggt
    46861 gagaaagagc gccatcacca cgcctaaatg gagcgccagc agtatgccca ttccgctggt
    46921 gtctctgcct gccagcagcg ccagcccggt aagactggtt aagaacagca gcagaataaa
    46981 gccgcgatcc atgggtttct ggcgcgcatc gctatgtaac ggcgaccgcc gcagattgag
    47041 ccacagtagc ccggccgggc cgataagcag accgataccg cccagcgtgc cgagcatgac
    47101 cggcaggcta aagaacgggt agggcgcttc ccaaccggcg acgtagtgat agcccgtcgc
    47161 cacgaccgtg gcggcaaaac agagcataaa accgtaaaag gtaaagtgat gaaagcgacg
    47221 gcgcagcagc gtgaacgcat cgtccgcttc gttacagcct ttgccgtgac cgccgtcgag
    47281 atatttcagc gttaacgcat tgtgcgacgc ttccgcaatc tccgccgaac gcggtacacc
    47341 cggcgagatc tcacgccaga agctgattac gcccgccata agcaaaccga ttgccagcac
    47401 aaaaactgag ccaaacatcc atgccagcag gctatgcgga aaaatttgat agaagtcacc
    47461 ggccagcggc ggatgaatca gcgacccttt cagcgccatc gccagtaata aaaagagcgt
    47521 cagaccgact atcagcgcca gcgcgacggt gatccccgcc cgacggtata acgcgccaaa
    47581 agcggcgggc tgggcatact gttgatacgt ctccaggcgg gcttgcgcca tcgctttcgg
    47641 cacgttaatg gcaaattcat ggggcggcgc gtactggcac gcgtgcaggc aggcgccgca
    47701 gttatgacat aaattcgcca gataatgaat atcggcttta ccgaattcga gccgctgggt
    47761 catcgccgga aataccgcgc aaaaaccttc gcagtagcga cacgcgttac acacttgcat
    47821 gacgcgttcg acctcggctt ccggttcggt aagcacggtg gcctcaatga ttaatttttc
    47881 aagctgtttc atgctgcgcc tccttgtgcg ccgcgcgagc ggcttctatt cccgcaatgc
    47941 ggccaaaggt tgtgccgata gacatgccta cgcctgcggt ataccccttg cccagaacat
    48001 ttcctgccat catctcgccg gcaacaaaca ggttgcggct tggatgaccg gcaaaatgca
    48061 ccgcggcacg ttcattgact ttcaggccca ggtaggtaaa cgtgatgccg ggtcgcagcg
    48121 cataaccgta gtagggcggc gcatcaagcg ggcgcgccca gtgggttttc gccggcgtca
    48181 ggtttttggt ggcgcagtca tcaagcaagg tatgatcaaa atgaccgggc tggcaggcct
    48241 ggttatactg cgtgacggta tgggtaaatt tttccgcgtc cagccccaac tggcaggcca
    48301 gttcagccag cgtattggcc tgcgcgccag gaaaaaccgg cggcataaag tggccaatgg
    48361 ctttgctgtc aataatcgaa tagccaattt gtcctggctg ttgagccacc agccgccccc
    48421 aaatggcgta acgcttcggc cagaaatctt cgccttcatc ataaaaacgc tcggcgtcgc
    48481 gattcacgac aatacccagc gatacgcaat ccacgcgagt acaaataccg ccgtcgtaca
    48541 gcggcgccct ggcatcaatc gctacgcagt gcgactggga cggatcgcca atgatatccg
    48601 cgccggcatc catcataaat ttgagtaata cgccctggtt aaaacgcgtg ccgcgaatca
    48661 ggaaattatc cgcgggccat tcgccgcggg cgttttctcc ccaggcctcc cgcagccatt
    48721 cacggtttga ttcgaaaccg ccagccgcta atacgcaggc tttggcggta atacgttcgc
    48781 tacccgccag cgccgccacg aattcgccgt catgaagttc aagcgcgtga accggcgtgt
    48841 tatagcgaat ctgtacgccc agccgttcgg cgctacggta ataggcattg acgagcgctt
    48901 tcccgccgcc cataaaaaac gcattggtgc gcgcaacgtg gagcgcccca gatagtggcg
    48961 gttgaaagtt aacgccatgt ttgcgcatcc agtcgcggca ttgcgaagag gtgcgaatga
    49021 ccagccgcgc cagcgcctcg ttggtgttgc cgtcggtgac tcgccacaga tcctgccaga
    49081 attcctcttc aggatagctt tccaccagca catcctgcgg cgcatcatgc atacagcgca
    49141 ggtttcgtgt gtgctgagaa tttccgccgc gccattctcg cggggcagcc tccagcagca
    49201 gaaccgatgc gcccgcttcc cgtgcggtca gggcggcgca taatgcggca ttgcctccgc
    49261 ctatcaccag tacatcaacc atcttatact cccgtaccat ttaactattt gttaaatttg
    49321 taattgaaat gtatacggat aaataagcgg cgcgctatca ggtagcgcta aacaggggtt
    49381 tagtaagcgt aaagggttgc gcctggccat tcaccggcgt cgactaactg acgcataact
    49441 ttggtaagga ctactctggc ggcaaggccg gcgggcgtca gttcatcatc cgacaggctg
    49501 actaaaaaat tggggcggct gagtaccgga ttatggacgc cgatcacgcg tagcgcgtcg
    49561 ttatccagat gagaaatcgc cgcgccgggc tgcaacgtgg cgccaagacc gtcgcgcacg
    49621 gcgcgcatca acaacgccag gccgtcaatt tccgcgacga tttcaacatt aagcgcatgt
    49681 tccttgcaga cagcgtccag cctgccgcgc agcccatgtc cctggcttgg cataatgagc
    49741 ggaatgcctg ccagttgttc aggtgtgatc gggttatcag gaagcgccgc cagcagggca
    49801 tgggagccaa tcagaaaaag ctgttcttca aggatcggtc tggcgctcca gcgcaggatt
    49861 ttatcttttt gaaagacaac ggctaaatca atctggcggg tattgatcat tctttccaga
    49921 ttaccggaca agctttccac cacatgcagt cggacatcgg catagttttc ctgcatggca
    49981 tggataaacg gtatacccag tatggaggcg gtactggggg ccattcctac gctcacatga
    50041 ccggaaaggc gcgcttctct ggcggcgaga atcgcgtcgt cggcatgacg cagggcgagt
    50101 tgcgcctgtg aataaaaggc cagcccggcg ttggttggcg ttacgccgcg cgaggtgcgc
    50161 tgcagcagac ggatggcgag ctcgttttcc agacgggaca tctgttgact caatgctgaa
    50221 acgccaatat caagatcctg tgcggcgctg cccatactgc cggtttcaat aatacgcacg
    50281 aaatagcgta actggcgaag ctccattcct gctctcctga gatgcgatag cgttttttac
    50341 attaaatcaa catcaagcgg caggaaagag gaggatataa aaaagccaac cgggcggttg
    50401 gctcttcgaa agatttacac ttatttagtc gcgtcatcgt gcgcgtgctc gtcttcgcgg
    50461 cagtcgcctt cagcgcagtg gccgtaaaga tagaggctgt gattagttaa acgaataccg
    50521 tgtttcgccg caatttcacg ctggcgcgct tcaatagagt catcactaaa ttcaatcact
    50581 tttccgcagt caaggcagat aagatggtcg tgatgatgct gttgcgtcag ttcaaaaacg
    50641 gatttaccgc cttcaaagtt atggcgggtc acgataccgg catcgtcaaa ctggttcagc
    50701 acacggtata cggttgccag accgatttct tcacccatgt cgatcaggcg tttgtataaa
    50761 tcttccgcac tgacgtgatg gttatctggt tcctgaagaa cttccagaat ttttaaacga
    50821 ggaagcgtta ctttcaggcc agccttcttt aatgcggtat tgttgtcagt catgcggaat
    50881 ctgtcctgtt gctaaacgat tcacttcatt agagaagtga cagaaattgc actcaagata
    50941 atgcgtatca ttataggact gccatgccga aatgaaaacc gcaagtctct cgcagatgtt
    51001 aataaaactg tggttttgcc tgcaaattct ggcgccacct gattacaccc ggacattgta
    51061 cagggatggg tgcgaaagtt acaaatttgt agcaattatt ttgattggtc ttgtctattg
    51121 atgcggcgca gatataacgc tgcgccgcat aagattaggc gttgaggatg tcgccgaggt
    51181 gcaattcagc cgaaacttgc ttaacccatt tttcaacacg ctcggcggtc agttcaggct
    51241 gacggtcttc gtcaatcgcc aggccgacaa aatgatcgtc gtcagccaga cctttagagg
    51301 cttcaaaatg atagcctgcg gttggccagt gacccacaat cgtggcgccg cgcggctcaa
    51361 taatgtcgcg aatcgtgccc agcgcatcac agaagtattc cgcgtagtct tcctgatcgc
    51421 cacagccaaa cagcgccacc agcttaccgt taaagtcaat ctcttcgaga gtcgggaaga
    51481 agtcatccca gtcacattgc gcttcgccat agtaccaggt tgggatgccc agcagcagaa
    51541 tgtcataccc ttctaggtct tctttactgc tttttgcaat gtcatgcaca tcggcaacgt
    51601 ctttaccaag ctgtttttga atcatttttg cgatattttc ggtattaccg gtgtcgctgc
    51661 cgaaaaagat gccagtgatt gccatgagta aaataacctc ttgaaactta ttgaaatggt
    51721 ggtggcgaat tgcccacgga taagggcaat catagcagaa caggcagata tgcggaaaca
    51781 gcaatcacgc gggactgcac gctctgctac acgaaatatg aaacaaaact tattttcaga
    51841 ctaaaccctg gccgcgcagc gccataagct gcttcattaa tatttcttca atgagctcgc
    51901 tgcggctaat gttgcgcgct tcggccagct cattcagcgc gtcaaccgct tgtgcgttga
    51961 gttttaattc gacacgcttg aggccacgaa ctttgtcgcg ttttaactgg ttgcgcttgt
    52021 tgatgcgtaa ctgttcatcg cgcgaaagcg gattcgtttt aggtcgtccc gggcgacgct
    52081 cgtgcgcgaa cagatctaat gtcgtacggt ccgtttgttc tttggccatg attttggtga
    52141 cttcggggga aacaatcagc caggcttatg cccggatgga tagcgcgcca tcatacatca
    52201 gcgaggaagc gacgccaacg ctcgcgcgcg taatcgcgca caggcgatga gtttttaatc
    52261 agttagcgtt tatcgtgcag ataacggcgg atggcgcgca gaaccgcctc tggtttttcg
    52321 gcatgtaccc agtggcccgc gccggcgatc acatgcgcgc gcgccaaagg gaattgcgcc
    52381 agcagcgcgt cgcggtacgc ttcggtcacg tacggcgagt taccgcctgg aataaacagc
    52441 gccggatgtt cccagggcgg aatggtttcc cagccgacga tatgcggata ctgctcccat
    52501 aataccggaa cattaaaacg ccattcgcct tcagcccagg attttaacag aaactggatc
    52561 acgccttctt tgttgaggtg ctggcgcata atccctgccg cctgttggcg ggatgtcgcg
    52621 tcggattcgc tgacggcgtt aatggccgcg aaaatgcgat cgtggcggcg aacgtgataa
    52681 tccacggggg cgatatcaat cgcgaccaga cgatcgatgc gatcgggcgc cagcgccgtc
    52741 agcgccatta ccgcttttcc acccatggaa tgaccaataa acgtcgcttt ttcaatctgc
    52801 tgcgcgtcaa gcgtatccag aagatcctgg gccattgccg gataatccat gaccggatcg
    52861 cgcggcgata aaccatgatt gcgcatatcg acctgaataa tgtcgtgatc ggtcaccaga
    52921 tcgcgcgcca gtacgccgag gttgtccagg ctgccaaaca ggccatgaac gagaacgatg
    52981 ggggaattat tgtgcaggtt ttgtgcagat tgcgctcgga tgtttaattt catggcaaag
    53041 ttcttttttt cgctctgtcg ggttagggta ttatgttgac cattctgcca ctgggctgca
    53101 acctctaagg tttactccga gtttttttgt cagccgggct taacgctatc cgctgttggg
    53161 atttgttcct ataatcccaa tgacttgtat tcagcaaaga catcgcactg gattaagatg
    53221 aaaacgattg aagttgatga tgaactctat agctatattg ccagccacac caagcatatc
    53281 ggcgagagcg catccgacat tttacggcgt atgttgaagt tttccgccac gacacagcca
    53341 acggcttcag cgatgaaggg gacgcctgcg gcgcaacccg ttgccgaagc gaaaccggtt
    53401 aacccggtaa aagacaaagt tcgcgcgatg cgtgagctgt tgttgtctga tgaatatgcc
    53461 gagcagaaaa aagcggtcaa ccgctttatg ctgattctga ctacactcta ttcactggat
    53521 caccacgcgt ttgcggaggc gacggagtcg ttgcatggcc gcacgcgcgt ctattttgcg
    53581 gcggatgaac aaacgctgct gaaaaatggg aatcaaacta aacctaagca cgttcccggc
    53641 acgccgtact gggtgatcac caacaccaac accggccgta aatgcagcat gatcgaacac
    53701 atcatgcagt caatgcaatt cccggcggaa ttgattgaaa aggtttgcgg aacaatttaa
    53761 tccttgcatt agaaggacca ggcaatggca atccacaacc gcgcaggaca acccgcgcaa
    53821 cagagtgatt tgattaacgt cgcccaactg acagcgcagt attatgtact gaaaccggag
    53881 gcagggaatg cagaacatgc cgtgaaattt ggcacttccg gccatcgcgg cagcgcaggt
    53941 cgtcacagtt tcaacgaacc gcatattctg gcgatcgccc aggcgattgc tgaagagcgg
    54001 gcgaaaaatg gcattaccgg cccctgctat gtggggaaag acacccatgc gctctcggaa
    54061 ccggccttca tttccgtgct ggaagtgctg gcggcaaacg gcgtagacgt tatcgtgcag
    54121 gaaaataatg gcttcacgcc aacgcctgcc gtgtcaaatg ctatcctggt ccataacaaa
    54181 aaaggcggcc cgctggcaga tggtattgtc attacaccgt cgcacaaccc gccggaagat
    54241 ggcggtatta aatataatcc gcccaatggc ggcccggcgg ataccaacgt cactaaagtg
    54301 gtagaagatc gcgccaatgc gctgctggcg gatggcctgc aaggcgttaa gcgcatctct
    54361 ctggatgcgg caatggcctc gggtcacgtt aaagcggtag atctggtaca gccgtttgtc
    54421 gaagggctgg cggatatcgt tgatatggcg gcgattcaga aagccggtct gacgctgggc
    54481 gttgatccgc tgggcggctc tggtattgaa tactggaaac gtatcgctga gcattacaag
    54541 cttaacctga cgttagtcaa cgatcaggtt gatcaaacct tccgctttat gcaccttgat
    54601 aaagatggcg cgatccgcat ggattgctcc tccgaatgtg cgatggcggg tttgctggcg
    54661 ctgcgtgaca agtttgacct ggccttcgcc aacgacccgg actacgaccg tcatggcatc
    54721 gtgacgcctg cagggctgat gaacccgaac cattatctgg cggtcgccat taactatctg
    54781 ttccagcatc gtccgctgtg gggcaaagac gtggctgtcg gtaaaacgct ggtctcttcc
    54841 gcgatgattg accgcgtggt gaatgatttg ggacgcaagc tggtagaagt gccggttggc
    54901 ttcaaatggt ttgttgacgg tttgttcgac ggcagctttg gtttcggcgg ggaagagagc
    54961 gcgggcgctt cgttcctgcg tttcgacggt acgccgtggt ctaccgataa agacgggatc
    55021 atcatgtgcc tgctggcggc ggaaatcacc gccgttaccg ggaaaaaccc gcaagagcat
    55081 tacaatgaac tggcagcgcg ttttggcgcg ccgagctata accgtctgca ggcggcagcg
    55141 acctcggccc agaaagcggc attgtctaaa ctgtctccgg aaatggtgag cgccagcacg
    55201 ctggcaggcg acccgattac cgcgcgtctt accgcagcgc cgggtaatgg cgcatcgatt
    55261 ggcggcctga aggtaatgac cgacaacggc tggttcgccg cgcgtccatc cggtacggaa
    55321 gacgcttaca agatctattg cgaaagcttc ctgggggaag aacatcgcaa gcagattgag
    55381 aaagaagccg ttgaaatcgt tagcgaagta ttgaaaaacg cctgatgggc gatatggaag
    55441 aaaaaggagc cttacggctc cttttttgta ttaacggcgc tgcgcttatc aggcctgtaa
    55501 accgcctcca ggccggataa ggcgcttgtg atatctgact tattcgctct gagtcgccag
    55561 atgtcggcgg caggtgaggg cgtcgcattc gatacgcacc acgcaaaccg ctttcatcat
    55621 atcttcccga taactgaagg tttttcccgg atcggtctgg cgcataatga cgtccaggcc
    55681 gtggcgcatc tcctcgcgcg tttgcaatat cgatgccagt ccggtggcga aaacgctggt
    55741 gtaggcgtag ctataatcac aggggtcatc ggcacgtagt aatgcatggt cgccgtccat
    55801 ttcaatgcat actgccgggt tcttacgtaa cagacgcatc tttttcccgg tgcgtgcgcc
    55861 gtgaaaataa aatatccagc gtccgttctg atactcgtag ccaaaattta cggggacaac
    55921 atacggacag agattgtcgt taaaccctat ccgacacact tcgtgtttac tgagaatagc
    55981 cagtatttct gctatatcag tgacttcccg ttctggatta ctcatttcta ttatcttatt
    56041 caaagagtga aaatgcccgg gctatcgtta ccgcagcccg ggcgcgccat cagccgtgtt
    56101 tatttttcaa ttcaaaacgc ggtgagacca ggccgtataa cgtccagccg aggaaggtca
    56161 caattgagcc gtacagcatg gcttcttcac cggaggaata tagcgcgtag aagctataca
    56221 tggcgccaac gaaggccacg aagttagcga ctttcgcttt tgatgatggc acattcgcca
    56281 ttttctgaat gataaccagc gcggccatcg acagaatata cggaataatg ttcgtcacca
    56341 ccgccaggtt aaccaggacg ttaaactgac tattcagcga cgggctaatg gtcatcagcg
    56401 acaggccagt ctgaataatc acaataatca gcatcccctg taccggcgcg tcgactttcg
    56461 ttacacgaga gaagactttc gggaaatagc cttcgtcagc ggaggattta aagacctggg
    56521 cgatagtgaa ctgccagccc agcagcgagc cgcagcagga cattaccatc agcgccatga
    56581 tcactttacc taccgcaggc gtgaacatct gtgcaaacgc cagaccaaac ggcgccgtgg
    56641 agttcgccag atccatgttc ggcacaatcc cggcaatcac gttagtcgaa acgatataga
    56701 tgaccgccgc gcccagcgta ccgcccagta ccgcgatggg gacgttcttt tccggattct
    56761 cgaccacgtc tgcgttagcg caggcggatt ccagtccaag aaatgcccac aacgtcatgg
    56821 cgatggaaga gccgaccgcg ctaaagaacg gaacatggtg cgggttccat gacgctacgt
    56881 acatgctggg gctaaaccag aaccagccaa tgatgcacag gccgacaacc ggaatgatga
    56941 cgccccaaac ggtaacgcta ctgatctgtc cggtaatacg cgcgccgcca aagtttgcga
    57001 tggtacaaac ccacaatacg gcgatagtcg ccagaccgat ctggagcggc gtcagcgcgg
    57061 cgccgaacag ttcggtacca tagccgacag cggagatggc gatagccacg ttggcgatca
    57121 gcagcgagac gccgtaggta tagttcgcca taaagttgcc ggatttaccg aaggcatatt
    57181 cggcgtaacc gcccatgccg ccggatttac ggctaaacat accgcatttc gcaaacgccc
    57241 aggccagcgc catcgagccg acggcggtga ccagccagga gataatggat atcgtgccga
    57301 cttcagacag tttggtcggt agcatgatga tcccggagcc catcatgttg accatagtca
    57361 gaattgtgag ctgcacgaca cccattttat tggatttagg tttactcata atttttcctc
    57421 cttcagcagg gagcgctgcg cgtcacgagg tttaatgacg tagcaccaga cctgcttacg
    57481 gccgtcgtgt tcttcgatat aaacgccctg cagttcaggc gcaaagcccg gcagcaggtt
    57541 gatcccttct tccagggcgc tgaagtaacg caggacagaa ccgccccaga tttcacccgg
    57601 aactacacac agcactcccg gcgggtaagg cagagcgcct tcagccgcga tacgaccttc
    57661 cgcttccggc aggcgaacca gttcgacctc gccgcgcaga taggcatagt tggcctcttg
    57721 cgggttcata ctgactttcg ggaaatgcga tttacggaac atctcttttt gcagctgttt
    57781 cacgttgtgc cgcgcataga gatcgtgcat ctcctggcaa agctgacgca gggtatagcc
    57841 ggcataacgc gcttcatgct gtttgtagat ggacggtaat acttccgcta acggcgcatc
    57901 agcttccagc agtttttcga aacgagccag cagagcgaca agctgttgta acttcgccat
    57961 gtcttctgcc ggcgtcagca ggaacagaat ggagttgagg tcgcattttt ccggcacaac
    58021 gccgttctcg cgcaggaagt tggcgaggat cgtggcagga acgccaaagt cttcatattc
    58081 gccgctcgct gcattaatgc ccggtgtggt gagcagcagt ttgcaagggt cgacaaagta
    58141 ctgatgttcg gcatagcctt caaacgcatg ccagtgttct cccggaacga agtggaagaa
    58201 gcgcagatcg ctggcgatct ctgacgttgg gtatgactgc cacggcttac catcaatcag
    58261 ttccggtacg aacggacgga tgtggtgaca gttttcgagg atcaatttac gggcatcgat
    58321 gccgttaact acgcaatcca tccacatatt gcgaccgctg acgccttcgt gcattttggc
    58381 gttaacgtcc agcgcggcga acagcggata gaacgggctg gtggaggcgt gcatcataaa
    58441 ggcgttgttc atgcgcttat gcggaacgta gcgcgattgc cctttgatat ggctatcttt
    58501 tttatggatc tgcgaggtct gggagaaacc ggcttgttgt ttgtgaacgg actgcgtcac
    58561 cagaataccc ggatcgtttt cgttcagttc cagcagcagc ggcgaacaat cggccatcat
    58621 cggaataaat tgttcatagc cgacccaggc ggagtcaaac aggatgtagt cgcacagatg
    58681 accaatttta tcgacgacct gacaggcgtt ataaatggta ccgtcgtagg tgcctaagta
    58741 ccgtcgtagg tgcctaactg gatgacggcc agacggaatg gacgtgcttc gtgggcacgc
    58801 tgcggcgcga cttcgctaat cagctcgcgc aggtaatctt cttcgaagca gtgagcgtcg
    58861 atcccgccga taaaaccata cggttacgcg cggtttccag ataaactggc gttgcgcccg
    58921 cctgcaataa tgcgccgtgg tggttagatt tgtggttgtt acggtcaaac agtaccagat
    58981 cgcccggcgt taacagcgcg ttgagtacga ctttgttaga ggaggaggtc ccgttcagca
    59041 caaagtaggt cttatcggcg ttaaagactt tcgccgccct gatgccccgg gcagtcaaat
    59101 gcgctgttgc cctggttgac ataatccacc agcgcgcgga aaaacggcgg acgtaactgc
    59161 gtttcgtagt ggcttgctgc ggtttccaac tggcgaccat agaaggcagt acgggattca
    59221 ttatattcga atacaccaga gatacgcggc aaatactcag gcggtacgcg tccttcgtca
    59281 tgagtcgcga caaacacggg aataccgtaa cccgttgcgt cgatttcatc gagttttccg
    59341 tgttcaatgt cgtcgatgga taacacggat gcagccacgt cgatgaaacg actctcatca
    59401 acatttacaa tattacggtg tgtagaaaaa caatccgggc aatgacggct aacggcaatt
    59461 tttaattctg acatttttca tctctttatt tcaggtaata gcaggccctc aatttctcgc
    59521 atgagaaact gattcttccg gaaaaaatca aagctatccc gctgataaaa aaatcagtaa
    59581 attagcttta ttttagatgt aataaatccc aacccgtccg gttgcaggaa attcaggatt
    59641 taaggagttg agtactacga tatacaggca gaaaccgcga taactaaaat tgcgctgagt
    59701 cggaatttct tctgtcaaac cacatagtta gctggctggg cgtaaaggaa ttaccgtact
    59761 gtcgctttta acaattcgag ttatttaggc aatagacctg aatgacataa gggtcggaaa
    59821 gacctgtatg ctgaagtacc cgtagcagaa aaaataccgg gcattaaaga aatgaaagtc
    59881 gaaactatta cggtgggcaa acatcataat atgcgttgtc cgccttatat ggggcataaa
    59941 acgattatta ttttccattt tgaggtcctt tcattgattt attgaaagca tggatatttt
    60001 atccagggag cgccagcaat ctgtgaacca gatcaacaaa aaacgatcat ttgaaaaata
    60061 attagtcggc gattatgcat atcgtgctgt gaa
//
LOCUS       DAJVKX010000008        56672 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000008 DAJVKX010000000
VERSION     DAJVKX010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 56672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56672
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.008"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            268..1398
                     /locus_tag="OPY25_000476"
     CDS             268..1398
                     /locus_tag="OPY25_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCS0926183.1"
                     /translation="MGQDSDDRRRTSSAGRVWQDHKDMVRQALRVSIPWFTFVNISFA
                     LIILFRHILISDFDKSISAQTGILPLIDDIMGSIIVFSFLILLFIYRLPARFTPLCLV
                     MLLILSLMWSYCSYCFIVWWQLPFAWPLSVILMLTALAALYYHLPALLLFIVPLWLTA
                     LLASVQLNQYVNIRFLLVWLTLTAILIYGRFILQRWFDEAWLRYQENRMLIARLDVMA
                     HQDALTGTANRRSMESFLGDALRQTEPFALIMLDVDYFKNYNDNYGHQAGDACLAKVA
                     CVVKRSIRTPADLVARYGGEEFVVVLPSSSLNEAALVAKRIQTNLRETALPHVASAVS
                     ETVTVSMGITLSTAGDTVTGIIARADEALYRAKQQGRNRWVK"
     gene            complement(1684..2079)
                     /locus_tag="OPY25_000477"
                     /pseudo
     CDS             complement(1684..2079)
                     /locus_tag="OPY25_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089414.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
     gene            2203..2564
                     /locus_tag="OPY25_000478"
                     /pseudo
     CDS             2203..2564
                     /locus_tag="OPY25_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415865.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            2566..2871
                     /locus_tag="OPY25_000479"
                     /pseudo
     CDS             2566..2871
                     /locus_tag="OPY25_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189081.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(3235..3588)
                     /locus_tag="OPY25_000480"
     CDS             complement(3235..3588)
                     /locus_tag="OPY25_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HCS0926184.1"
                     /translation="MKKILLPALLLATSGVALAAPQVITVSRFEVGKDKWAFNREEVM
                     LTCRPGQALYVINPSTLVQYPLNAIAEQQVAEGKTRAQPIAIIQIDNPAKPGEKMSLA
                     PFIERAQKLCDPSNS"
     gene            complement(3605..4480)
                     /gene="copD"
                     /locus_tag="OPY25_000481"
     CDS             complement(3605..4480)
                     /gene="copD"
                     /locus_tag="OPY25_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HCS0926185.1"
                     /translation="MMLTFVWITLRFIHFASLMLVYGCALYGAWLAPASIRRLMTRRF
                     LHLQRHAAAWSVISAAFMLAIQGGLMGGGWPDVFSVSVWGAVLQTRFGAVWIWQIILA
                     LVTLAVVVIAPVKMQRRLLILTVAQFILLAGVGHATMRDGVAGTLQQINHALHLLCAA
                     AWFGGLLPVVYCMRMAQGRWRQHAISAMMSFSRYGHFFVAGVLLTGIGNTLFITGFTA
                     IWQTTYGQLLLLKCALVVLMVAIALTNRYVLVPRMRQENPRTDLWFVRMTQIEWGVGG
                     IVLAIVSLFATLEPF"
     gene            complement(4481..4855)
                     /gene="yobA"
                     /locus_tag="OPY25_000482"
     CDS             complement(4481..4855)
                     /gene="yobA"
                     /locus_tag="OPY25_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HCS0926186.1"
                     /translation="MASSAPSRRLALLLLASTFATPAAWAHAHLTHQYPAANAAVTAS
                     PQALTLNFFEGIEPGFSGATITGPQQESIKTRPAKRNEQDKTQLIIPLEQPLKSGAYT
                     VDWHVVSVDGHKTKGKYTFSVK"
     gene            4993..5223
                     /locus_tag="OPY25_000483"
     CDS             4993..5223
                     /locus_tag="OPY25_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HCS0926187.1"
                     /translation="MKTNLAQLEQAEMDKVNVDLAAAGVAFKERYNMPVVAEAVEREQ
                     PEHLRAWFRERLIAHRLASVSLSRLPYEPKVK"
     gene            5331..5987
                     /locus_tag="OPY25_000484"
     CDS             5331..5987
                     /locus_tag="OPY25_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HCS0926188.1"
                     /translation="MSSWKIAAAQYAPLNASPAEHVAHHLEYIELAARQQCELLVFPS
                     LSLLGCDERNKPLPAPPDEALLQPLTHAADTHHMTIIVGMPVEHNCRFVKGIAIFAPW
                     LTSPLMFHKSHGACIARQRSAINVVDEQPEGGDIGPSFTLFTTSQCLNEPELHASTSR
                     LQRFSHKYALAVLMANACGSSALWDESGQLIVRADCGSLLLTGLRTTEGWQGDIIPLR
                     "
     gene            6011..6709
                     /gene="exoX"
                     /locus_tag="OPY25_000485"
     CDS             6011..6709
                     /gene="exoX"
                     /locus_tag="OPY25_000485"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HCS0926189.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGNIVNPMSHLIRPDRPIT
                     PQAMAIHRITEAMVADKPWIEDVIPLYYGSEWYVAHNASFDRRVLPELPGEWICTMKL
                     SRRLWPGIKYSNMALYKSRKLSVQTPPGLHHHRALYDCYITAALLIDIMRTTGWTAEE
                     MVNITGRPALLTTFPFGKYRGKAVSEVAKRDPGYLRWLFNNLDNMSPELRLTLKHYLE
                     DVQAGEQRSNGTPQ"
     gene            complement(6746..8797)
                     /gene="ptrB"
                     /locus_tag="OPY25_000486"
     CDS             complement(6746..8797)
                     /gene="ptrB"
                     /locus_tag="OPY25_000486"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HCS0926190.1"
                     /translation="MLPKANRIPYAMTVHGDTRIDNYYWLRDDTRSQPEVLDYLHQEN
                     EYGRKVMSSQQALQDRILKEIIDRIPPREVSAPYVKNGYRYRYIYEPGCEYAIYQRQS
                     ALSEEWNVWETLLDANQRAAHSEFYTLGGLAITPDNTIMALAEDYLSRRQYGLRFRNL
                     ESGNWYPELLDNVAPEFVWANDSLTLYYVRKHKKTLLPYQVWRHTIGTPSSQDELVYE
                     EKDDTFYVSLHKTTSQHYVVIHLASATTSEVLLLDAELADAEPFSFLPRRKDHEYSLD
                     HYQHKFYLRSNRNGKNFGLYRTRVRNENAWEELIPPREHIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWLAYNPEPETSRLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDSGCYQSEHLWITARDGVEVPVSLVYHQKYFRKGQNPLLVY
                     GYGSYGSSIDADFSSSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKRNTFNDY
                     LDACDALLKLGYGSPSLCYGMGGSAGGMLMGVAINERPELFHGVIAQVPFVDVLTTML
                     DESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDNVKAQDYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDQRLLLLCTDMDSGHGGKSGRFKSYEGVALEFAFLIGLAQGTLHS
                     A"
     gene            complement(9011..9670)
                     /locus_tag="OPY25_000487"
     CDS             complement(9011..9670)
                     /locus_tag="OPY25_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HCS0926191.1"
                     /translation="MANWLNQLQSLLGQKGASASPSGEQGLNKLLVPGALGGLAGLLV
                     ANKSSRKLLTKYGTGALLVGGGAVASSVLWNKYKDKVRAAHQGEPQFGSQSTPLDIRT
                     ERLILALVFAAKSDGHIDAKERAAIEHQLRESGVEEQGRVFIEKAIEQPLDPQRLAQG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQEVRDGIEQDLQQQKQALP
                     G"
     gene            complement(9764..10117)
                     /locus_tag="OPY25_000488"
     CDS             complement(9764..10117)
                     /locus_tag="OPY25_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926192.1"
                     /translation="MNKRGALLSLLLLSASVSAFAASTESKSVKFPQCEGLDAAGIAA
                     SVKRDYQQNRIVRWADDQKKVGQADPVAWVNVQDVVGQNDKWTVPLTVRGKSADIHYQ
                     VIVDCKAGKAEYKPR"
     gene            complement(10185..10475)
                     /gene="yebG"
                     /locus_tag="OPY25_000489"
     CDS             complement(10185..10475)
                     /gene="yebG"
                     /locus_tag="OPY25_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HCS0926193.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAWDKMLDTADLLDTWLEQ
                     SPVVLEDGQREALSLWMAEHKEVLSTILKTGKLPSPQAVEKDAASKTKKQAA"
     gene            10606..11784
                     /gene="purT"
                     /locus_tag="OPY25_000490"
     CDS             10606..11784
                     /gene="purT"
                     /locus_tag="OPY25_000490"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HCS0926194.1"
                     /translation="MTLLGTALRPAATRVMLLGAGELGKEVAIECQRLGIEVIAVDRY
                     PDAPAMHVAHRSHVINMLDGEALRHVITEEKPHYIVPEIEAIATDTLRELEGEGLNVV
                     PCARATQLTMNREGIRRLAAEELGLPTSTYRFADSEASFHDAVAAVGFPCIVKPVMSS
                     SGKGQSFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQQDGDYRESWQPQQMSELALKRAQEIARHVVLALGGHGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGMPIGAIRQYGPAASAVILPQLTSQN
                     VTFDDVHAAVGAGVQVRLFGKPEIDGTRRLGVALATGENVEEAVIRAKKAASRVTVKG
                     "
     gene            complement(11884..12525)
                     /gene="kdgA"
                     /locus_tag="OPY25_000491"
                     /gene_synonym="eda"
     CDS             complement(11884..12525)
                     /gene="kdgA"
                     /locus_tag="OPY25_000491"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCS0926195.1"
                     /translation="MKNWKTSAEAILTTGPVVPVIVVNKLEHAVPMAKALVAGGVRVL
                     EVTLRTACAMDAIRAIAKDVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATAGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGTKALQAIAGPFSQVRFCP
                     TGGISLANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKQ"
     gene            complement(12563..14374)
                     /gene="edd"
                     /locus_tag="OPY25_000492"
     CDS             complement(12563..14374)
                     /gene="edd"
                     /locus_tag="OPY25_000492"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HCS0926196.1"
                     /translation="MNPNLLRVTQRIVERSQQTRKAYLARIEQAKTATVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPQIIRQALHSVNAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LAMAALSFGHLPAIFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDAPLREALTAAAARQVTRLTGNGNTWM
                     PLGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGILINWDDFSDLSEVVPLMA
                     RLYPNGPADINHFQAAGGVPVLMRELLNAGLLHEDVNTVAGFGLKRYTLEPWLNNGEL
                     DWREGAERSLDNDVIASFDKPFSPHGGTKVLSGNLGRAVMKTSAVPVENQIIEAPAMV
                     FESQHDVLPAFDAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRRFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARQ
                     PHIPDLSASRVGTGRELFGALREKLSGAEQGATCITF"
     gene            complement(14609..16084)
                     /gene="zwf"
                     /locus_tag="OPY25_000493"
     CDS             complement(14609..16084)
                     /gene="zwf"
                     /locus_tag="OPY25_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCS0926197.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQIHPDTR
                     IIGVGRADWDKEAYTHVVREALETFMKEKIDEGLWDTLSGRLDFCNLDVNDTPAFSRL
                     GDMLDQKNRTTINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSREIN
                     DRVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDQAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGQKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPR
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            16426..17295
                     /locus_tag="OPY25_000494"
     CDS             16426..17295
                     /locus_tag="OPY25_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCS0926198.1"
                     /translation="MNMLEKVQSQLEHLSKSERKVADVILAAPGRSIHLSIAMLAQEA
                     NVSEPTVNRFCRSMNTRGFPDFKLHLAQSLANGTPYVNRNVDEDDSVEAYTGKIFESA
                     MASLDHVRQSLDKSAVNRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVIYS
                     DDIVLQRMSCMNCNDDDVVVLISHTGRTKSLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKELLIRSDDR"
     gene            17419..18861
                     /gene="pyk"
                     /locus_tag="OPY25_000495"
     CDS             17419..18861
                     /gene="pyk"
                     /locus_tag="OPY25_000495"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCS0926199.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCDQNAMDDIILASDVVMVARGNLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSAADGVVAAHEAVNLLRDKGY
                     LVSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(18934..19905)
                     /gene="lpxM"
                     /locus_tag="OPY25_000496"
                     /gene_synonym="msbB"
     CDS             complement(18934..19905)
                     /gene="lpxM"
                     /locus_tag="OPY25_000496"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460846.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HCS0926200.1"
                     /translation="METKKNNSEYIPEFEKSFRYPQYWGAWLGAAAMAGIALTPASFR
                     DPLLATLGRFAGRLGKSSRRRALINLSLCFPQRSEAEREAIVDEMFATAPQAMAMMAE
                     LAMRGPKKIQQRVDWEGLEIIEEMRRNDEKVIFLVPHGWGVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYIWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVIPLFPVYNGKTHRLTIQIRPPMDDLLTADDHT
                     IARRMNEEVEIFVGPHPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(20022..21341)
                     /gene="mepM"
                     /locus_tag="OPY25_000497"
     CDS             complement(20022..21341)
                     /gene="mepM"
                     /locus_tag="OPY25_000497"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HCS0926201.1"
                     /translation="MQQIAGSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHPE
                     SAPIVKTIELEKSEIRSLLPEASEPIDQAAQEDEAIPQDELDDKTAGEVGVHEYVVST
                     GDTLSSILNQYGIDMSDISRLAASDKELRNLKIGQQLSWTLTADGDLQRLTWEVSRRE
                     TRTYDRTANGFKMSSEMQQGDWVNSLLKGTVGGSFVASAKEAGLTSSEISAVIKAMQW
                     QMDFRKLKKGDEFSVLMSREMLDGKREQSQLLGVRMRSDGKDYYAIRAADGKFYDRNG
                     VGLAKGFLRFPTAKQFRISSNFNPRRLNPVTGRVAPHRGVDFAMPQGTPVLSVGDGEV
                     VVAKRSGAAGYYIAIRHGRTYTTRYMHLRKLLVKPGQKVKRGDRIALSGNTGRSTGPH
                     LHYEVWINQQAVNPLTAKLPRTEGLTGSDRREYLAQVKEILPQLRFD"
     gene            complement(21357..22301)
                     /gene="znuA"
                     /locus_tag="OPY25_000498"
     CDS             complement(21357..22301)
                     /gene="znuA"
                     /locus_tag="OPY25_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HCS0926202.1"
                     /translation="MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIAD
                     GVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVWVGPEMEAFMEKSVRNIPDNKQV
                     TIAQLADVKPLLMKGADDDEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAV
                     AIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYE
                     KHYGLTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTS
                     VRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD"
     gene            22380..23135
                     /gene="znuC"
                     /locus_tag="OPY25_000499"
     CDS             22380..23135
                     /gene="znuC"
                     /locus_tag="OPY25_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HCS0926203.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELSPGKILTLLGPNGAGKS
                     TLVRVVLGLVAPDEGVIKRNGQLRIGYVPQKLYLDTTLPLTVNRFLRLRPCTQKTDIL
                     PALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLNHHICCSGAPEVVSMHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNGHS"
     gene            23132..23917
                     /gene="znuB"
                     /locus_tag="OPY25_000500"
     CDS             23132..23917
                     /gene="znuB"
                     /locus_tag="OPY25_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HCS0926204.1"
                     /translation="MIELLLPGWLAGMMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLASGLVWLEKRPHLAIDTLLGIMAHSALSLGLVVVS
                     LMSNVRVDLMAYLFGDLLAVTPEDLISIAIGVVIVLAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVTMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     GVGMIAVTGGLTFSAFYDTPAGPSVVLCAALLFIFSMMKKQAS"
     gene            complement(23996..25006)
                     /gene="ruvB"
                     /locus_tag="OPY25_000501"
     CDS             complement(23996..25006)
                     /gene="ruvB"
                     /locus_tag="OPY25_000501"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCS0926205.1"
                     /translation="MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIF
                     IQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGAISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPE
                     MP"
     gene            complement(25015..25626)
                     /gene="ruvA"
                     /locus_tag="OPY25_000502"
     CDS             complement(25015..25626)
                     /gene="ruvA"
                     /locus_tag="OPY25_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCS0926206.1"
                     /translation="MIGRLRGIILEKQPPIVLLETGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREELGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAVDLVLTSPASPTSEDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIRDALRAAL"
     gene            complement(25986..26678)
                     /locus_tag="OPY25_000503"
     CDS             complement(25986..26678)
                     /locus_tag="OPY25_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926207.1"
                     /translation="MVDDKPMKIGWVFYFSYIFVAIIFHLFISFCYCLSIDMAEANTV
                     VFLLKPGTISLLFLLLPARRFRTRLLATLSSVFIALVFNQWHLVAGNKELVLCMQAAC
                     FMAFLAMTSVKKSGWMISASLFLVCAAGTIRQCWLEQLFNAADIYIVDDGRSCGASGH
                     CFQYIAAKGRGLAAKRQALFNSEEYVNIYYSYSEGIPAVNFDGMKNEFAQYLLCHGEL
                     KYVVRDDKTTCD"
     gene            26888..27487
                     /locus_tag="OPY25_000504"
     CDS             26888..27487
                     /locus_tag="OPY25_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HCS0926208.1"
                     /translation="MKKHYPVQYETGDIVFTCIGAALFGQISTASQCWSNHVGIIIGH
                     NGDDYLVAESRVPLSTVTTLSLFIQRSAGQRYAVRRLCGGLTVEQKLAIMEQVPARLN
                     KFYHTGFKYESSRQFCSKFVFDIYKEALCIPVGDIETFEELLHSNPDAKLTFWKFWFL
                     GSIPWDRKTVTPASLWQHPNLELISACGIENPQREAEGE"
     gene            complement(27489..28010)
                     /gene="ruvC"
                     /locus_tag="OPY25_000505"
     CDS             complement(27489..28010)
                     /gene="ruvC"
                     /locus_tag="OPY25_000505"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HCS0926209.1"
                     /translation="MSIILGIDPGSRITGYGVIRQVGRQLTYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(28047..28787)
                     /locus_tag="OPY25_000506"
     CDS             complement(28047..28787)
                     /locus_tag="OPY25_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCS0926210.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAVDKALANNMTRDTLNRAIARGVGGDEDSNMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLLR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(28817..29269)
                     /gene="nudB"
                     /locus_tag="OPY25_000507"
     CDS             complement(28817..29269)
                     /gene="nudB"
                     /locus_tag="OPY25_000507"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HCS0926211.1"
                     /translation="MKDKVYKRPVSVLVVIFAQDTKRVLMLQRRDDPDFWQSVTGSIE
                     EGETALQTAVREVKEEVTIDVAAEQLTLVDCQRTVEFEIFSHLRHRYAPGVMHNTEFW
                     FCLALPHERQVIFTEHLTYQWLDAPDAAALTKSWSNRQAIEEFVINVA"
     gene            complement(29372..31144)
                     /gene="aspS"
                     /locus_tag="OPY25_000508"
     CDS             complement(29372..31144)
                     /gene="aspS"
                     /locus_tag="OPY25_000508"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCS0926212.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDAKNVNADMATGEIEVLASSLTII
                     NRADSLPLDANHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGAQLSRKQI
                     DDYGNFVKIYGAKGLAYIKVNERAKGLDGINSPVAKFLTADIVEAILERTGAQDGDMI
                     FFGADNKKVVADALGALRLKLGKDLSLTDEDKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTAPRDMTASELKTAPEEAVANAYDMVINGYEVGGGSVRIHNGEMQQTVFGILGINEQ
                     EQREKFGFLLDALKYGTPPHVGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANQAALTELGIQVVKKAENN"
     gene            31469..32035
                     /locus_tag="OPY25_000509"
     CDS             31469..32035
                     /locus_tag="OPY25_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCS0926213.1"
                     /translation="MLKLNATTTALVVIDLQEGILPFAGGPYTANEVVARAARLAEKC
                     RANGSPVVMVRVGWSDDYAEALKQPVDAATPAHALPENWWTWPTALGKKDSDLEVTKR
                     QWGAFYGTDLELQLRRRGIDTIILCGISTNIGVESTARNAWELGFNLIIAEDACSAAS
                     SEQHQSSMTHIFPRIGRVRSVEDILNAL"
     gene            32032..32850
                     /locus_tag="OPY25_000510"
     CDS             32032..32850
                     /locus_tag="OPY25_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCS0926214.1"
                     /translation="MIYIGLPQWSHPKWARLGITSLEEYARHFNCVEGNTTLYALPKA
                     EIVDRWYAQTTDDFRFCFKFPATISHQAALRHCDDLVQAFFTRLAPLETRIGQYWLQL
                     PAAFGPRDLPALWQFLDALPATFTYGVEVRHPCFFDKGEDEQRLNRGLHARGVNRVIL
                     DSRPVHAAHPHSEAVRDAQRKKPKVPVHAVVTASHPMVRFIGSDNMAQNREFFAAWLQ
                     KLPQWRQTTTPFLFLHTPDIAQAPELVNTLWHDLRSVLPEIGTAPSIPQQSSLF"
     gene            32903..33298
                     /locus_tag="OPY25_000511"
     CDS             32903..33298
                     /locus_tag="OPY25_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HCS0926215.1"
                     /translation="MVSALYAVLGALLLMKFSFNVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPVALVLLLFMEMNGAETWMVHICGIILIAGRLMHYYGFHHRLFRWRRA
                     GMSATWCALLLMVLANLWYMPWELVFSLY"
     gene            33339..34082
                     /gene="cmoA"
                     /locus_tag="OPY25_000512"
     CDS             33339..34082
                     /gene="cmoA"
                     /locus_tag="OPY25_000512"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HCS0926216.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPNTQVYDLGCSLGAATLSVRRNIRHEHCRIIAVDNSPAMIERCRRHI
                     DAYKAPTPVEVVEGDIRDITIENASMVVLNFTLQFLEPAERQALLDKIYLGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     RQAGFEHSELWFQCFNFGSLVALKAGVAA"
     gene            34079..35050
                     /gene="cmoB"
                     /locus_tag="OPY25_000513"
     CDS             34079..35050
                     /gene="cmoB"
                     /locus_tag="OPY25_000513"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HCS0926217.1"
                     /translation="MIEFGNFYQLIAKNHLSHWLETLPAQIAAWQREQQHGLFKQWSN
                     AVEFLPEITPWRLDLLHSVTAESETPLSEGQLKRIDTLLRNLMPWRKGPFSLYGVDID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHLWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVVDGDENTVLVPGDRYAQMRNVYFIPSAPALKKWLEKCGFVDVRIADVC
                     VTTTEEQRRTEWMVTESLADFLDPNDRSKTVEGYPAPQRAVLIARKP"
     gene            complement(35286..36033)
                     /gene="cutC"
                     /locus_tag="OPY25_000514"
                     /pseudo
     CDS             complement(35286..36033)
                     /gene="cutC"
                     /locus_tag="OPY25_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
     gene            complement(36053..36622)
                     /locus_tag="OPY25_000515"
     CDS             complement(36053..36622)
                     /locus_tag="OPY25_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCS0926218.1"
                     /translation="MANWQHIDELHDISADLPRFTLAFRELSTRLGLQINALEADHIS
                     LRCHQNTTAERWRRGFEQCGELLSENIINGRPICLFKLHEPVCVEHWRFSVIELPWPG
                     EKRYPHEGWEHIEIVLPGEPETLNARALALLSDEGLSQPGIVVKTSSPQGEHERLPNP
                     TLAVTDGRVTVKFHPWSIEAIVASEQAAH"
     gene            36859..38592
                     /gene="argS"
                     /locus_tag="OPY25_000516"
     CDS             36859..38592
                     /gene="argS"
                     /locus_tag="OPY25_000516"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCS0926219.1"
                     /translation="MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLSGIASKVEIAGPGFINIFLEPAFLAEQVQQALTS
                     DRLGVSQPTRQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGDMALADLEGFYRDAKKHYDEDETFAERARNYVVKLQ
                     SGDTYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRTGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKADIDEQALASAPVIISEDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDVAGLFSGFYEHCPILSAENDAVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            38781..39950
                     /gene="mrdA"
                     /locus_tag="OPY25_000517"
     CDS             38781..39950
                     /gene="mrdA"
                     /locus_tag="OPY25_000517"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR03423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCS0926220.1"
                     /translation="MTFKDFDAEEKLFLRRVIVAFGVVVVCFGILIFNLYNLQIRQHH
                     YYTTRSNENDIKMLPVAPTRGIIYDRNGIPLVRNVTWYDIAVTPYKIADMDALLKQLT
                     PIVDLSPDDIADFRRALKSSSRYRPVVLKNALTDVEIARFAVNQFHFNGVTINSYQDR
                     QYPYGAELAHVLGYVSKINDNDLKALDKKGLAENYAADHNIGKQGIERYYENDLHGKT
                     GYQEVEVDNHGRIVRLLKDVPPIAGKNIHLTLDLHLQEYIESLLAGQRAAVLVEDPHD
                     GSVLAMVSMPSYDPNPFVKGISYQDYGKLLHDKNLPLINRVTQGLYPPASTVKPYMAM
                     SALLCGIITPQTTFFGAPTWTLPGTQRHYRDWKKTGHGMLDVTKAIEESADTFFY"
     gene            39960..40652
                     /locus_tag="OPY25_000518"
     CDS             39960..40652
                     /locus_tag="OPY25_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000971841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCS0926221.1"
                     /translation="MMGIDRIDTMLSQFGYGKPTGIDLSEEYDGLLPSRAWKQRVHKK
                     AWYQGDTISVGIGQGYWIATPIQMVKAMVALINNSKVIAPHLLLNEESGKTVVPYRPS
                     GTPAQIADPASPYWGLVRQAMYGMANAPNGTGYKFFHTAPYGIAAKSGTSQVFSLKEN
                     QTYNAKMIPIRLRDHVFYTAFAPYKNPKVAIALILENGGSDGVTAAPIMRKILDHLFD
                     PQADTTQSGQAP"
     gene            complement(40706..41845)
                     /locus_tag="OPY25_000519"
     CDS             complement(40706..41845)
                     /locus_tag="OPY25_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 105 protein"
                     /protein_id="HCS0926222.1"
                     /translation="MMVYPVKHSPLLRQPEHFIARDELKALVQKVTHNLVNIKDETGE
                     FLLRLDDGRVIDTKGWAGWEWTHGVGLYGMYHYYQQTGDQTMRKIIDDWFADRFAEGA
                     TTKNVNTMAPFLTLAYRYEETRNPAYLPWLETWAEWAMNEMPRTDYGGMQHITLAEEN
                     HQQMWDDTLMMTVLPLAKIGKLLNRPEYVEEATYQFLLHVQNLMDKETGLWFHGWSYD
                     GHHNFANARWARGNSWLTIVVPDFLELLDLPENNAVRRYLVQVLNAQIAALAKCQDES
                     GLWHTLLDDPHSYLEASATAGFAYGILKAVRKRYVERHYAQVAEKAIRGIVKHISPEG
                     ELLQTSFGTGMGHDLDFYRHIPLTSMPYGQAMAMLCLTEYLRNYF"
     gene            complement(42082..42474)
                     /gene="flhe"
                     /locus_tag="OPY25_000520"
     CDS             complement(42082..42474)
                     /gene="flhe"
                     /locus_tag="OPY25_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HCS0926223.1"
                     /translation="MRKWLALLLFPLTVQAAGEGAWQDSGMGVTLNYRGVSASSSPLS
                     ARQPVSGVMTLVAWRYELNGPTPAGLRVRLCSQSRCVELDGQSGTTHGFAHVPAVEPL
                     RFVWEVPGGGRLIPALKVRSNQVIVNYR"
     gene            complement(42474..44552)
                     /gene="flhA"
                     /locus_tag="OPY25_000521"
     CDS             complement(42474..44552)
                     /gene="flhA"
                     /locus_tag="OPY25_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HCS0926224.1"
                     /translation="MANLVAMLRLPSNLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NVVGGLLVGVLQHGMSMGSAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVGQLFSNPRVMLLAAAVLGLLGMVPGMPNLVFLLFTAALLGLAWWLRGREEKA
                     PEEPQPVKMPENNSVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQDMGFLPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLP
                     GEKTVDPAFGLDAIWIESALKEQAQIQGFTVVEASTVVATHLNHLIGQFSAELFGRQE
                     AQQLLDRVSQEMPKLTEDLVPGVVTLTTLHKVLQNLLAEKVPIRDMRTILETLAEHAP
                     LQSDPHELTAVVRVALGRAITQQWFPGNEEVQVIGLDTALERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(44545..45696)
                     /gene="flhB"
                     /locus_tag="OPY25_000522"
     CDS             complement(44545..45696)
                     /gene="flhB"
                     /locus_tag="OPY25_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HCS0926225.1"
                     /translation="MAEESDDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVC
                     IIWFGGESLARQLAGMLSAGLHFDHRMVNDPNLILGQIILLIKAAMMALLPLIAGVVL
                     VALISPVMLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVT
                     GFYLWNHWPQMMRLMAESPIVAMGNALDLVGLCALLVVLGVIPMVGFDVFFQIFSHLK
                     KLRMSRQDIRDEFKESEGDPHVKGKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVA
                     LQYDENKMSAPKVVAKGAGLIALRIREIGAEHRVPTLEAPPLARALYRHAEIGQQIPG
                     QLYAAVAEVLAWVWQLKRWRLAGGQRPPQPENLPVPEALDFMNEKNTDG"
     gene            complement(45890..46534)
                     /gene="cheZ"
                     /locus_tag="OPY25_000523"
     CDS             complement(45890..46534)
                     /gene="cheZ"
                     /locus_tag="OPY25_000523"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HCS0926226.1"
                     /translation="MMQPSIKPADEGSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLDYVVQMTAQAAERALNSVEASQPHQDAMEKEAKALTQRWDEWLDNPI
                     ELSDARELVTDTRQFLRDVPGHTSFTNAQLLDIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQSARPKRENESLLNGPQVDTSKAGVVASQEQVDDLLDSLGF"
     gene            complement(46545..46934)
                     /gene="cheY"
                     /locus_tag="OPY25_000524"
     CDS             complement(46545..46934)
                     /gene="cheY"
                     /locus_tag="OPY25_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HCS0926227.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGFGFIISDWNMPNMDGLELLKTIRADSAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(46952..48001)
                     /gene="cheB"
                     /locus_tag="OPY25_000525"
     CDS             complement(46952..48001)
                     /gene="cheB"
                     /locus_tag="OPY25_000525"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HCS0926228.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAARARIAAHKPMAAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPAVIITQHMPPGFTRSFAERLNKLCQISVKEAEDGE
                     RVLPGHAYIAPGDKHMELARSGANYQIKIHDGPPVNRHRPSVDVLFHSVAKHAGRNAV
                     GVILTGMGNDGAAGMLAMYQAGAWTIAQNEASCVVFGMPREAINMGGVSEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(47998..48864)
                     /gene="cheR"
                     /locus_tag="OPY25_000526"
     CDS             complement(47998..48864)
                     /gene="cheR"
                     /locus_tag="OPY25_000526"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HCS0926229.1"
                     /translation="MTSSLPSGQTSVLLQMTQRLALSDAHFRRICQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRALGLDDFGRYLSMLEANQNSVEWQAFINALTTNLTAFFREAHH
                     FPILAEHARRRHGEYRVWSAAASTGEEPYSIAITLADALGMAPGRWKVFASDIDTEVL
                     EKARSGIYRLSELKTLSPQQLQRYFMRGTGPHEGLVRVRQQLANYVEFSSVNLLEKQY
                     NVPGPFDAIFCRNVMIYFDKTTQEDILRRFVPLLKPDGLLFAGHSENFSNLVREFSLR
                     GQTVYALSKDKA"
     gene            complement(49025..50686)
                     /gene="tar"
                     /locus_tag="OPY25_000527"
     CDS             complement(49025..50686)
                     /gene="tar"
                     /locus_tag="OPY25_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HCS0926230.1"
                     /translation="MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISN
                     ELRQQQSELTSTWDLMLQTRINLSRSAARMMMDASNQQSSAKTDLLQNAKTTLAQAAA
                     HYANFKNMTPLPAMAEASANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNA
                     LGEALGNYARVSENLYRQTFDQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLN
                     PLARVITHIREIASGDLTKTLTVSGRNEIGELVGTVEHMQRSLIDTVTQVCEGSDAIY
                     SGTSEIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASET
                     ARHGGKVVDGVVNTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMTDIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLASRPLAVNKPEMRLSVDAQSGNTPRPLAAGDDANWETF"
     gene            complement(50923..51426)
                     /gene="cheW"
                     /locus_tag="OPY25_000528"
     CDS             complement(50923..51426)
                     /gene="cheW"
                     /locus_tag="OPY25_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HCS0926231.1"
                     /translation="MTGMSNVSKLAGEPSGQEFLVFTLGNEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCEGDVEYDDNTVVIVLNLGQRVVGIVV
                     GGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGERMLILVNIEKLLNSEEMALLD
                     IAASHVA"
     gene            complement(51447..53462)
                     /gene="cheA"
                     /locus_tag="OPY25_000529"
     CDS             complement(51447..53462)
                     /gene="cheA"
                     /locus_tag="OPY25_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HCS0926232.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIF
                     RAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPR
                     DESKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLC
                     FVIEADQIAFEKVVTAPVEKAQEKTEVAPVASPAVVAPAAKSAAHEHHAGREKPARER
                     ESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDLITSMGQLQRNARDL
                     QESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLT
                     HLVRNSLDHGIEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAK
                     AMSQGMAVNENMTDDEVGMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEI
                     QSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLHPLAGGE
                     RVLEVRGEYLPLVELWKVFDVDGAKTESTQGIVVILQSAGRRYALLVDQLIGQHQVVV
                     KNLESNYRKVPGISAATILGDGSVALIVDVSALQGLNREQRMAITAA"
     gene            complement(53467..54396)
                     /gene="motB"
                     /locus_tag="OPY25_000530"
     CDS             complement(53467..54396)
                     /gene="motB"
                     /locus_tag="OPY25_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HCS0926233.1"
                     /translation="MKNQAHPIVVVKRRRHKPHGGGAHGSWKIAYADFMTAMMAFFLV
                     MWLISISSPKELIQIAEYFRTPLATAVTGGNRIANSKSPIPGGGDDYTQQQGEVEKQP
                     NIDELKKRMEQSRLNKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRP
                     MFKTGSAEVEPYMRDILRAIAPVLNGIPNRISLAGHTDDFPYANGEKGYSNWELSADR
                     ANASRRELVAGGLDNGKVLRVVGMAATMRLSDRGPDDAINRRISLLVLNKQAEQAILH
                     ENAESQNEPVSVLQQPAAAPPASVPTSPKAEPR"
     gene            complement(54393..55280)
                     /gene="motA"
                     /locus_tag="OPY25_000531"
     CDS             complement(54393..55280)
                     /gene="motA"
                     /locus_tag="OPY25_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HCS0926234.1"
                     /translation="MLILLGYLVVIGTVFGGYVMTGGHLGALYQPAELVIIGGAGMGA
                     FIVGNNGKAIKGTMKAIPLLFRRSKYTKSMYMDLLALLYRLMAKSRQQGMFSLERDIE
                     NPKESEIFASYPRILADAVMLDFIVDYLRLIISGNMNTFEIEALMDEEIETHESEAEV
                     PANSLAMVGDSLPAFGIVAAVMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLATVLRQKSAETTKMMQCVKITLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVRNPNQQQTTEEA"
     gene            complement(55408..55986)
                     /gene="flhC"
                     /locus_tag="OPY25_000532"
     CDS             complement(55408..55986)
                     /gene="flhC"
                     /locus_tag="OPY25_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HCS0926235.1"
                     /translation="MSEKSIVQEARDIQLAMELINLGARLQMLESETQLSRGRLIRLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNIHASMFCNAWQFLLKTGLCSGVDAVIKAYRLY
                     LEQCPQPPEGSLLALTRAWTLVRFVESGLLELSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSRDAADIIPQLLDEQIEQAV"
     gene            complement(55989..56330)
                     /gene="flhD"
                     /locus_tag="OPY25_000533"
     CDS             complement(55989..56330)
                     /gene="flhD"
                     /locus_tag="OPY25_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310629.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HCS0926236.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAN
                     TLGALTLPQMVKLAETNQLVCHFRFDDHQTITRLTQDSRVDDLQQIHTGIMLSTRLLN
                     EVDDTARKKRA"
BASE COUNT        13230 a        15679 c        14279 g        13484 t
ORIGIN      
        1 ctatttatgg atacaaataa gtcgtgtttt acgtctgcca gttacatcct cttttagtaa
       61 gtggggtaaa ctcgcttcca gtttccggga aacactataa ttctcccccc tactacagga
      121 attgtgacta taagttcgtc actgtggagc aaaaatcatc tcatcagcca aaaatgcagc
      181 ctggcctgat agcttttcca tttttcacca tgaagtatct ccgcactaca ctggatagta
      241 attattcatt atatgaggcg attaaggatg gggcaggatt cggacgacag gcgccgtacc
      301 tccagtgctg gaagggtatg gcaggatcat aaagatatgg tcaggcaagc gctacgtgta
      361 agtattccgt ggttcacatt tgtgaatatc agctttgcgc ttatcatttt atttcgccac
      421 atactcatca gtgactttga caagtcgatc agtgcacaga ctggaatact gcctttaata
      481 gacgatatta tgggcagtat tattgttttt tcgttcctga tactcctttt catttaccgc
      541 cttccggcca gatttactcc tctttgtctg gtgatgctgc tgattctcag tctgatgtgg
      601 agctattgta gctactgttt tattgtctgg tggcaactgc cttttgcctg gcctctcagt
      661 gtcatcctta tgcttaccgc gctggctgcg ctttattatc atctgccagc gttgctactt
      721 ttcatcgtcc cgttatggct gaccgcccta ctggccagcg tgcagcttaa ccagtatgtg
      781 aatatccggt ttttattagt ctggcttact cttaccgcca tactcattta tggtcgcttt
      841 atcctgcagc gctggtttga tgaagcctgg ttgcgttacc aggaaaaccg gatgcttatc
      901 gcgcgtctcg acgttatggc tcaccaggat gcactgaccg ggaccgctaa tcgacgttca
      961 atggaaagtt ttcttgggga tgctctccgc cagacggagc cgtttgcact gatcatgctc
     1021 gatgtggact atttcaaaaa ctataacgac aattatggtc accaggctgg cgatgcctgt
     1081 ctggcaaagg tggcctgtgt agtaaagagg tcgattcgta ctccggcaga cctggtggca
     1141 cgttacgggg gcgaggagtt tgtcgttgtg ctgccttcgt cgtcgctgaa tgaagctgca
     1201 ctggttgcta aacgtattca gacaaacctg cgtgaaaccg cactgccgca tgtagcatct
     1261 gcggtaagcg aaacggtcac cgtcagcatg ggcatcaccc tttccacagc cggtgacact
     1321 gttaccggca ttattgccag agcggatgag gccctttatc gggctaaaca acagggacgt
     1381 aatcgttggg taaagtaaaa ccagttgccc ggtgtttgat acagaagatc accttgccat
     1441 actcagataa ttaaaactga atatttggaa gcaaaaaaga cagtcggact cacggaacct
     1501 ttgcgctggt acagcctgaa tatcagataa aattatgtcc agccgcagac accagttgac
     1561 agtggaatat tcctggtgtt gtgaacaagg cgacattcac aacacgactg tgctcacgga
     1621 attcaaatgc caaacggatg attacgatat tcgctacctc tgcaaagtta tattattcga
     1681 ttttcatgca gatttcgcct cccggtaatt tccccgataa aatgccagta ccctttgcat
     1741 cgtcacgctg ttccggcact ccgtacagat aacgtttctg gtccggtcgt aggaactcac
     1801 gacaccttcc ggcgttttca gaaagcgggt aatcctggca tcttcacgtt tctacttcca
     1861 aagcaggaaa gcctgttccg aaggaaaaat accgcttctc ccggcctgat acagatcccc
     1921 acaactttcc gccttttcca ggtagtgacg ggctgtaaaa atggttaacc ctgttatctt
     1981 ccgaagttct ccaaacgtca tccgaccgtg tgttcgtacc agttccgtca ggcgcttttg
     2041 tatttcagct ttctgcgccg gtgtgtaatt tctgctcata agtcccccca gttaaagcct
     2101 tcccgccgcc ttacgccgtc tgaatttttc catcatcagt tgtgccgggg ttggccctgc
     2161 cggatgacgc ggcgctgcaa gttgacggcg taccggcggt atgccacaac ggaaatccga
     2221 aaagttccgg cgctgggtga ctgtgacacc atgagttttg tcagcgccat cgttcagtgt
     2281 tcccagcttg ggctggaacc cggcggcgcg ctcggtcatg cctatctgct gccgttcgga
     2341 aacaaaaacg aaaagtcagg caaaaaaacg ttcagttaat tattggctac cggggaatga
     2401 tcgaccttgc ccgccgttcc ggacagattg ccagcctttc cgcgcgcgtt gtccgtgaag
     2461 gtgacgattt cagcttcgag tttggtctgg aagagaagct ggtacaccgt ccgggtgaga
     2521 acgaagatgc acaggttact catgtctatg ccgttgcccg ccttaatcga tcgctgccga
     2581 ctggtaagcc gaactgattt catgatcagt gccggaatca ggaaaaatag cccaaccggg
     2641 aatattcacc cggatgggct gacaaagaaa tttgtaaaag ccagaaaaat ttcaggcgtt
     2701 aaatgtagtg ataacccacc gacatttcac aagatccgta gcctggctgg tcggctgtac
     2761 aaaaacgaac gcggcgagga attcgctcaa aaactactgg gccacacctc agagaacacc
     2821 acgaaactct atctcgatga acgcgataat aaagcttacg tgatgctctg attttgttgt
     2881 aaaagaaatg ttaaactgaa tttgattgtg atataaccaa aaagaccgga atacagaaat
     2941 tcgaggaaat ttcgagggaa aacacataac ccgttgattt ataatcgaaa taaaaagaga
     3001 ccgaatacga ttcctgtatt cggtccaggg aaatggctct tgggagagag ccgtgcgcta
     3061 aaagttggca ttaatgcagg ctaaatcgcc ttgctcttta agaatagatg acgacgccag
     3121 gttttccagt ttgtgacgaa ggtgattgaa aaaacctggc gtattgtctg tcatcagaga
     3181 taaaaaaacc gtaagccttt tcgtgaaggt ttacggtttt ttattaaaaa tcagtcagct
     3241 attggatgga tcacaaagct tttgcgcacg ttcgataaac ggcgccagac tcattttctc
     3301 accgggcttt gccgggttat cgatttgaat gatggcaata ggctgagcgc gcgttttacc
     3361 ctccgctact tgctgctcgg caatagcatt caagggatac tgcaccagag tactggggtt
     3421 gatcacatag agcgcctggc caggccgaca ggtcaacatg acctcttccc gattaaacgc
     3481 ccacttgtct tttcctactt caaaacgact tacggtaatc acctgcggcg ccgccaacgc
     3541 tacgcccgaa gtggccagca gaagcgccgg aaggagtatt tttttcattc gttatgccag
     3601 tccatcagaa aggttcgagg gttgcaaaca ggctgacgat cgccagaact atgcctccaa
     3661 ctccccattc aatttgcgtc atcctgacaa accataggtc agtccgggga ttttcctgtc
     3721 gcatacgtgg tacgagaaca taccgattcg tcagcgcaat tgctaccata agcaccacca
     3781 gcgcacattt taacaaaagc aactgtccat aagtggtctg ccagatagcg gtaaatcccg
     3841 tgataaatag cgtgttgcca atgcctgtga gcaatacgcc cgccacaaaa aagtgaccat
     3901 aacgagaaaa actcatcatg gcgctaatgg catgttgacg ccagcgtcct tgagccatgc
     3961 gcatacaata aaccactggc aacagcccgc caaaccaggc tgcggcacag agcaaatgca
     4021 gagcatggtt aatttgctgt aatgttcccg ctacaccatc gcgcatcgtc gcatgtccaa
     4081 cgcctgccag caggataaac tgagcaacgg ttagaataag aagccgtcgt tgcattttta
     4141 ccggcgcaat gactaccacc gccagcgtga ccagcgcgag gataatttgc catatccaga
     4201 ccgcgccaaa gcgggtttgc agtaccgcgc cccaaaccga gacggaaaaa acatcgggcc
     4261 agccgccgcc catcagtccg ccctgaattg ccagcataaa agccgcgctg ataacgctcc
     4321 aggcggcggc atgtcgttgc agatgtaaaa atcgacgcgt cattaaacga cgaattgatg
     4381 cgggtgccag ccaggcgccg taaagcgcgc agccgtagac cagcatcaaa ctagcaaaat
     4441 gaataaatcg gagagttatc cagacgaatg tcagcatcat ttatttcacg ctgaaggtgt
     4501 atttcccttt tgttttatgt ccatccaccg acacaacgtg ccagtctacc gtgtaagcgc
     4561 cagattttaa cggctgctca agcgggataa tcaactgcgt tttatcctgt tcatttcgct
     4621 ttgccgggcg cgttttgatg gactcttgct gagggccagt aatggttgcg ccgctgaatc
     4681 ctggctcaat cccttcaaaa aagttcagag tcagcgcctg tggcgaggcc gtaacggcag
     4741 cattcgctgc tggatactga tgcgtcaggt gcgcatgtgc ccaggccgct ggcgtcgcaa
     4801 atgtcgatgc cagcagcagt aaagctaaac gtcgcgatgg tgcagaagaa gccatattca
     4861 ctattccttt ttgttatacc tacgttacaa agaataacct tcaacaatca atgagtcgag
     4921 gatcatcatt tccatcttgc cattgccgcg gactcttagt accttctggc ggcaacaaaa
     4981 aaggagacac gtatgaaaac gaatctggct cagcttgaac aagcggaaat ggataaagtc
     5041 aatgtggatc tggcggcagc tggggtggca tttaaagagc gctacaatat gccagttgtc
     5101 gcggaggcgg tcgaacgtga gcagccagag catctacgcg cctggtttcg cgagcggctg
     5161 attgcccatc gtctggcttc cgtatcacta tcccgactcc cttacgaacc caaagttaaa
     5221 taaaaattat ataacgttac acttccttac atgcagacga ctacattata aggcgattct
     5281 taacctatgc tttttagaat ggctgtagag actatgaaaa ggaagtcatt atgtcctcct
     5341 ggaaaattgc cgctgcgcag tacgcgcccc tgaacgcttc gccggcagag catgtcgccc
     5401 atcatctgga atatattgag cttgcggctc gtcaacagtg cgaactgctg gtctttccgt
     5461 cactgtcgct attaggctgc gacgaaagaa ataaaccgtt gcccgccccg cctgacgagg
     5521 cgcttttaca gccgctcact catgcggccg atacccacca tatgactatc attgtgggta
     5581 tgcctgttga gcataactgc cgcttcgtaa aaggcatcgc tatttttgcc ccatggctaa
     5641 cgtcgccgct catgtttcac aaaagtcatg gcgcctgtat tgccaggcag cgaagcgcta
     5701 tcaacgtggt ggatgagcag ccagaaggtg gtgatatagg cccctcattt acgttattca
     5761 caaccagtca atgtcttaac gagcctgaac tccatgcttc tacctcacgc ttacaacgtt
     5821 tttcgcataa atatgcgctg gccgtactga tggccaatgc ctgtggcagt agcgcgctgt
     5881 gggatgaaag cgggcaactt attgttcgtg ccgattgcgg ttcgctatta ctgacgggtc
     5941 tgcgcacaac cgagggttgg caaggcgata tcattccatt acgctaaggt ctttgggtga
     6001 ggaatgaatc atgttgcgga ttatagacac ggaaacctgc gggctgcagg gcgggatcgt
     6061 agagatagcc tctgtagatg tcattgatgg caacattgtc aatcccatga gtcacctgat
     6121 acgccccgat cgccctatta cgccgcaggc gatggcgata caccgtatta ccgaagccat
     6181 ggtcgccgat aagccgtgga ttgaagatgt cataccgctt tattacggta gtgagtggta
     6241 tgtcgctcac aatgccagtt tcgacagacg cgtattacct gaattgccgg gtgagtggat
     6301 ctgtaccatg aagttgtcgc gacgcctgtg gccgggaata aaatacagca atatggcgct
     6361 ctataaatcg cgcaaactaa gcgtacaaac gccgccgggg ctgcaccatc accgggcgct
     6421 ttatgattgc tatatcaccg ccgccttgct gattgatatt atgcgaacca ccggctggac
     6481 cgcggaagag atggtcaata tcacgggccg tcctgcgctg ttaaccactt tcccgttcgg
     6541 taaataccgc ggtaaggcgg tatctgaagt cgcaaaacgc gatccgggct atttacgctg
     6601 gctttttaat aaccttgata atatgagccc ggaacttcgc ctgacgctta aacactacct
     6661 ggaagatgtt caggctggcg agcaacgcag caatggaaca ccacaataac ccgcgacgct
     6721 cacaagccgt tgcgggcgcg cgcgtctatg cgctatgtaa ggttccctgc gccaggccga
     6781 ttaaaaaggc gaactccagc gcgacgcctt cgtaggattt aaaccgcccc gacttaccac
     6841 cgtgcccgga gtccatatcc gtacataaca gcagcagacg ttggtccgtt tttagctcgc
     6901 gtaattttgc cacccacttc gccggttccc agtattgcac ctgggaatcg tgcaatcctg
     6961 tcgtcaccag caggtgcgga tagtcctgcg ctttgacatt gtcataagga ctatagcttt
     7021 tcatatagtc ataatactca atatcctgcg ggttccccca ctcttcaaac tcccctgtcg
     7081 ttaatgggat cgactcatcc agcatcgtgg ttaatacatc aacaaagggc acctgggcaa
     7141 taacgccgtg gaaaagctcg gggcgttcgt tgatagcgac gcccattagc attccgcccg
     7201 cgctcccgcc catcccataa cacagcgacg gtgaaccgta acccagtttt aataaggcat
     7261 cgcaggcatc aagatagtca ttaaaagtat tccgcttttt gaggaatttg ccatcttcat
     7321 accactgctg ccccagctca ccgccgccgc gaacgtgtac gattgcgtaa acaaagccac
     7381 gatccagcaa gctcagtcgg ctgctgctga agtcggcgtc aatactggaa ccgtaagatc
     7441 cgtaaccgta aaccagaagc ggattttgcc ctttacgaaa atacttctga tgataaacca
     7501 gcgataccgg cacttcgacg ccgtcgcgtg cggtgatcca caggtgttcg ctctgataac
     7561 agccagaatc aaacccaggt acttccgtct gtttaagtac ccgtcgttct ccggtatcca
     7621 tatccagttc aaacaaggta tctggcgtcg tcattgaaga atagccgtaa cgcagccggg
     7681 aggtctcagg ttcgggatta taggcaagcc acgtcacgta agccggatcg tcaaaggcaa
     7741 tgcctatcac ttcacgggtt ttacggttaa tttgccgcag gctggtaagc ccccgttgac
     7801 gctcttcgac cactaaccag tcggtaaaca gggtaaaccc ttccagcata atatgctcgc
     7861 gcggagggat cagctcttcc caggcgtttt cattgcgcac gcgggtacgg tacaacccaa
     7921 agtttttacc gttccggtta gagcgcaggt aaaacttatg ttgatagtga tcgagactat
     7981 attcatggtc tttgcggcgc ggtaagaatg aaaacggctc ggcatcggcc agttccgcgt
     8041 caagtaatag cacttcgcta gtggtggcgc tggcaagatg aatcaccaca taatgctgcg
     8101 aagtggtttt atgcaggctg acataaaagg tatcgtcttt ctcctcatat accagttcat
     8161 cttgcgatga cggagtgcca atcgtgtgcc gccaaacctg atagggcagc agcgtcttct
     8221 tatgcttacg cacatagtaa agagtcaggg aatcattggc ccagacaaat tcaggcgcaa
     8281 cgttatccag cagttccgga taccagttac cgctttcgag gttacgaaaa cgcaacccat
     8341 actgacgacg ggataaataa tcttctgcca gcgccatgat ggtattatcc ggcgtaatgg
     8401 caagcccgcc gagcgtataa aattcgctgt gcgcggcccg ctggttcgca tcgagcaagg
     8461 tttcccacac attccactct tcgcttaacg ccgattgtcg ttgatagatg gcatattcgc
     8521 agccgggttc atagatataa cggtagcgat agccgttttt cacatacgga gcggaaactt
     8581 ctctgggcgg gatgcgatcg ataatttctt ttagaatgcg gtcctgtaac gcctgctgag
     8641 aggacatgac cttccggcca tactcatttt cctgatgcag gtaatcaagg acttccggct
     8701 gcgagcgagt gtcatctcgc agccagtaat aattatcaat gcgcgtatcg ccatgtacgg
     8761 tcatggcata gggaattcga ttggcttttg gcaacatgtc gttttttctt ttgcgttaat
     8821 atttgttata tatcacgcgg caaacacagc ggcttagcat ggtagtcccg gtccgctcac
     8881 ctcggtaagc gcctgagatg tcactgcttc gccgctatct tgcaacatga atgacgtaaa
     8941 ctatccatcc tataagggtg gcaaaagaca cgcatgatgc aagcgaaaca tgttacttaa
     9001 tggcaggtta tcagcctggt agcgcctgtt tttgctgctg caagtcctgc tcgataccgt
     9061 cccgaacctc ctgaggaatt tttagcgcgt ctcctaacgc attcagatag ctacgttcca
     9121 taaagtggtc aatatcaatg gcggcgcagc tcaggaagta gatttccagg gcttcttctt
     9181 cattgcgaac gccctgtgcc agacgttgtg gatcaagcgg ctgctcaata gctttctcga
     9241 taaacacacg cccttgctct tccacacctg attctcgcag ttggtgctca atcgccgcgc
     9301 gttctttggc atcaatatgc ccatcgcttt ttgcagcaaa aaccagcgct aggatcagtc
     9361 gctcagtgcg aatatccagc ggcgtacttt ggctgccgaa ttgcggctcc ccctgatgcg
     9421 cagcgcgtac tttatctttg tacttattcc acaatacgga actcgccacc gcgccgccgc
     9481 ccaccagcaa agcgccagta ccgtatttgg ttaataattt gcgcgaagac ttattggcga
     9541 ccaacagtcc agccagaccg cccagcgcgc cgggaaccag cagtttattt aacccctgtt
     9601 caccggaagg cgatgcagaa gcgccttttt gcccaagaag tgattgtaat tggttcaacc
     9661 agttagccat agtacccctc aaatacagac caataatggt caagcgtacc tgaggggatg
     9721 tcaggaattg tctgttccgg caaaagaagc gcaaattacg ctgctagcgg ggcttatatt
     9781 ccgccttgcc ggctttgcaa tcaacgatga cctgataatg gatatcggcg cttttaccgc
     9841 gaacggttag cggaacggtc catttatcat tttgacccac aacgtcctgc acattaaccc
     9901 acgcgaccgg gtcagcctgc ccgacctttt tttggtcgtc tgcccaccgc acgatacgat
     9961 tttgctggta gtcgcgcttc acgcttgccg caatcccggc ggcatccagc ccttcgcact
    10021 gcggaaactt aaccgattta ctctcggtgg atgccgcaaa tgccgatacg ctggcggata
    10081 acaacagcag gctcaacaac gctcctcttt tattcatact tttctcctta gcacaatgat
    10141 tcaggaaaag catggtacaa aacgccgaga gcgcaagtgt gggttcaggc ggcttgcttt
    10201 ttcgttttac tcgcggcgtc cttttcaacc gcctgcggag aaggcaactt accggttttg
    10261 aggatcgtgc ttaacacctc tttatgttcc gccatccaca gcgacaacgc ctcgcgctgc
    10321 ccatcttcca gcacgactgg cgactgctca agccaggtat caagaagatc ggcagtatcg
    10381 agcattttgt cccaggcgtc ggcttccttt ttactggtaa atgacatctt ctcctcaccc
    10441 tcgcgaatga ctacgtattt aacttcaacc gccattttgc agccccttat ttacctgtgt
    10501 ttatatacag tatattgcaa ggcggcaaga aaagcaattt attcgaaaag acatacgcaa
    10561 acgttttcgt atatactgcg cgcaggtaaa taaggggaca gaaatatgac gctattaggc
    10621 actgcgctac gtccggcagc aacgcgggtg atgttattag gggcaggtga attgggaaaa
    10681 gaggtggcga ttgaatgcca acgcctgggg atcgaggtta tcgccgtcga tcgctatcct
    10741 gatgctcccg ccatgcatgt ggctcaccgt tcacacgtca ttaatatgct ggacggcgag
    10801 gcgctacgtc atgtgattac agaggaaaaa ccgcattata tcgtgccgga aatagaagcg
    10861 atcgccaccg atacgctgcg cgagctggag ggcgaagggc tgaatgtcgt gccttgcgcc
    10921 cgtgcaacgc agctcacgat gaaccgcgaa gggatccgtc gcctggccgc agaagaatta
    10981 ggtctgccga catcgacgta tcgctttgcc gacagtgagg ccagttttca tgatgcggta
    11041 gccgcagtgg gttttccttg catcgtcaaa ccggtcatga gctcttccgg caaaggccag
    11101 agctttatcc gctcggccga acagctcgcg caggcatggg agtatgctca acagggcgga
    11161 cgcgctggcg cgggtcgcgt gattgtggaa ggcgtggtta aatttgattt tgaaattacg
    11221 ctgctcaccg ttagcgccgt cgatggcgtg catttctgcg cgccggtcgg tcatcgtcag
    11281 caagatggtg actatcgcga atcctggcaa ccacagcaga tgagcgaact ggcgctgaag
    11341 cgggcgcaag agattgctcg tcatgtggta ctggcgttag gcggtcatgg tctgttcggc
    11401 gttgaactct tcgtctgtgg cgatgaagtc attttcagcg aagtctcccc tcgcccgcac
    11461 gataccggaa tggtcacgtt gatttctcag gatctttctg agtttgcgct gcatgtgcgc
    11521 gcctttctgg gaatgcccat aggcgctatt cgccagtatg gtcccgctgc ctcggccgtg
    11581 attctgccgc agcttaccag tcaaaatgtg acgtttgatg atgtacacgc ggcggtaggg
    11641 gccggagtgc aggtacggct gtttggtaag cctgagatcg acggcacccg tcgtcttggt
    11701 gtagcgttag cgacaggtga aaacgttgaa gaagcggtga taagagcgaa aaaggccgcc
    11761 agccgcgtga cggtaaaagg ctaatgcgcc atcgcctgat ggcgacgtta gcgcattttt
    11821 atcaggcctg cctgatcgcc actcgtaagc ccgataagca agcgccatcg ggcatttaac
    11881 ggcttactgc ttcgcgcctt ctaccgcttc gcgcgccagt ttggtgatgc gatcgtaatc
    11941 acccgcttcc agcgcgtcgg ccggcaccag ccaggaaccg ccgatgcaca acacgctttt
    12001 cagcgccaga tagtcacgat agtttgccag agagatgccg ccggttgggc agaaacgtac
    12061 ctgagagaac ggaccggcaa tcgcctgcaa cgctttagtg ccgccattcg cttccgccgg
    12121 gaagaatttg aactctttca gaccatagtc catgcccaac atcagttcag aaacggtgct
    12181 aataccggga atcaatggga tagtgcctgc cgtcgcggct ttcagcagtg gctcagtcag
    12241 tcccgggcta atcgcaaact gcgcgcccgc ctccgtcacc tccgccaact gctgcggatt
    12301 gagaacggtt ccggcgccga caatcgcttc cggcacgtct ttagcgatag cgcgaatagc
    12361 atccatcgcg caggccgtac gtaaagtcac ttccagaacg cgaacgcccc cggccaccag
    12421 cgctttagcc atcggcaccg cgtgctccag tttattgact acaatgaccg ggacaaccgg
    12481 gccggtggtc aggattgctt ctgcacttgt tttccagttt ttcatcggaa ttcttctctc
    12541 gcctgattac tagtgtgtca tcttaaaaag tgatacaggt tgcgccctgc tccgcacccg
    12601 acagcttttc gcgcagcgcg ccaaacaact cacgccccgt tccgacgcgc gacgcgctca
    12661 ggtccggaat atgaggctga cgagcggcaa gttccgcctc gtcgaccagc agagttaact
    12721 cacctgtctg cccattcacg cgaatgatgt cgccatcgcg cacttttgcc agtaagccgc
    12781 catcgtaggc ttccggcgtt acgtggatag ctgaaggcac tttacccgaa gcgcctgaaa
    12841 gtcgtccatc agtaactaac gcgattttga aacggcggtc caataataca ccaagtggcg
    12901 gcatgagttt atgtaattct ggcattccat tcgcttttgg tccctgatga cgcacgacaa
    12961 cgacacaatc ccggtcaagc aggcccgcgt caaacgcagg cagcacatca tgctgacttt
    13021 caaataccat ggcaggcgct tcaatgatct ggttttcaac cggtaccgca gacgtcttca
    13081 ttactgcgcg ccccagatta ccgcttagca ccttagtacc gccgtgagga gagaacggct
    13141 tatcaaaaga ggcaatgaca tcgttatcca gtgacctttc cgcgccttca cgccagtcca
    13201 gctcgccgtt gttgagccag ggctccagcg tatagcgttt caggccgaag cctgcgacag
    13261 tattaacgtc ttcgtgcagc aatccggcat tgagcagctc acgcatcaat accggcacgc
    13321 cgcccgccgc ctggaagtgg ttaatgtccg ccggaccgtt cgggtacaga cgcgccatca
    13381 acggaaccac ttccgacaaa tccgagaagt catcccagtt gatcagaatg cccgccgcgc
    13441 gcgccattgc aaccagatgc atggtgtggt tggtggaacc gccggtagcc agcagcgcga
    13501 caatgccgtt caccacgact ttttcgtcga tcattttacc gagcggcatc cacgtattgc
    13561 cgttgccggt aagacgtgtt acctgacgtg cggcagcggc agtcaatgcc tcgcgcagcg
    13621 gcgcatccgg atgcacaaac gaggaacccg gcaactgcat tcccataaac tccaccacca
    13681 tctggttggt gttggcagtg ccgtaaaatg tacaggtgcc cggcgcatgg taagaggcgg
    13741 cttccgactc cagcagcgcc attctgtcta cttttccttc cgcatatagc tgacgaatac
    13801 ggactttttc tttattcggc aggccgctcg ccatcgggcc tgacggaaca aaaatcgcgg
    13861 gtaaatgacc aaaagagagc gcggccatcg ccagccccgg aacaattttg tcgcatacgc
    13921 cgaggaataa cgcgccgtca aacatattgt gagaaaggcc tactgctgcc gacatcgcta
    13981 tcacttcgcg gctgagtaat gacaactcca tgccatcctg cccttgcgta acgccatcgc
    14041 acattgccgg tacgccgcct gcgacctgac ctaccgcatt cacggaatgc agggcctgac
    14101 gaataatctg cggataatgt tcatacggtt gatgcgcaga gagcatgtca ttgtaggagg
    14161 taatgatggc gatattattg cgcaacatac ttttcagcga ggctttgtcc tctggctgac
    14221 aggcggcgaa gccatgcgcc aggttgccgc aggccagttg agatcggtgg accgtggcgg
    14281 ttttcgcctg ctcaatgcgg gcaagatagg cttttcgggt ctgctgcgag cgttcgacaa
    14341 tgcgctgtgt tacgcgtaac aaattaggat tcatagaggc tcctgaaatt tatctgtccg
    14401 gctaccgggt ttaccatgcg tttcatcaat gtggaaagac agtgaaatac atgatgtccg
    14461 gggataatgg ggcaaaatcg tttcaggcag tgtaataaaa aaagcctcgc aggtgaatcc
    14521 acacgaggct taaaagtgca aaaatgattc tacaatctgt gttagatcat gttaccggta
    14581 aaataccacc taagagtgag tggcaaattt actcaaactc attccacgaa cgaccgtcac
    14641 gggtaatcat cgccacggac gctaccggtc cccaggtgcc cgcctgatac ggcttcggcg
    14701 cgtcgttgtc catcgcccat gcttcggtaa tggagtccac ccacttccag gcttcttcca
    14761 cttcgtcacg gcggacaaac agcgcctgaa tgccacgcat cgtttccagc agcaggcgct
    14821 catatgcatc cgccaggtgc gtctgattaa aggtctcgga gtagctcaga tcaagcttcg
    14881 tgatttgcag attatgctta tgatccagcc tcggtacttt gttaagtacc tgaatatcta
    14941 cgccttcatc cggctgcagg cgaatcgtca atttgttctg cggcaggtct tgccaggact
    15001 ctttaaagag attcagttca ggcgtcttga aataaaccac gacttcagag cacttagttg
    15061 gcagacgctt gccggtgcgc agatagaatg gcacgcccgc ccaacgccag ttatcgatgt
    15121 cgacgcggat cgcgacgaaa gtttcggtgt tgctgctttt attcgcgccc tcttcttcca
    15181 gatagcccgg caccttttga ccctgcgcaa agcccgcggt gtattgacca cgaaccgttt
    15241 tttcacgcac gttggagcga tcaatacggc gcaacgattt caacactttt actttttcat
    15301 cgcgaatact gtcggcgctc aggtcagacg gcggtgacat ggcaatcatg cagagaattt
    15361 gcagcaagtg gttctggatc atatcgcgca tctgaccggc ctggtcaaaa tatccccagc
    15421 gcccttcaat ccccacctct tccgctacgg taatctcaac gtgatcgata gtgcggttat
    15481 cccagttatt aacgaataac gagttggcaa aacgcagcgc cagcaggttg agaaccgttt
    15541 ctttgcccag atagtggtcg atacgatata cttggcactc ttcaaagtat tcgccgaccc
    15601 gatcgttaat ctcacgcgag gtcgccagcg aagtacccaa cggtttctcc atcacgacac
    15661 gcgccggttt ggcgttgagt ttagcctccc ctaacccttt gcaaatagcg ccaaacgtgc
    15721 tgggcggcat cgcaaaatag ttaatggtgg tgcggttttt ttgatccagc atatcgccca
    15781 ggcgactgaa cgcaggcgta tcgttaacgt caagattaca aaaatccaga cggccgctca
    15841 gcgtatccca caagccttca tcaatttttt ccttcatgaa ggtttccagc gcctcacgca
    15901 caacgtgggt ataagcttct ttatcccagt ccgcgcgccc caccccaatg atccgggtat
    15961 ccggatggat ctggccggct ttctcaagct gatacaggga aggcagcagt ttccggcgcg
    16021 ccaggtcgcc tttcgcgccg aaaatgacca ggtcacatgc ctgggctgtt tgcgttaccg
    16081 ccatgtcatt ctcctcagtt aatctcctgg tactttagcc aggatatcgt tgtaatttta
    16141 ttacacagca ctgtactgct tttacgagat tacggaaacc gtaaacgcct tttcataggt
    16201 gaaccggcgt ttgattggca atataatcgg caaaacgcct aataaaattg tcgcttttcc
    16261 acacaagctg gaacttaaaa tccgacgtcg gtcatgtaat gaaaaaaaac gacacctttt
    16321 ttagccattt tgcccccttt gacagccgcc aggagtaata tctaacaaaa cgcgctcggt
    16381 ttcgcgcatc attgaaatcg ctaataccca tgagccttgc taatcatgaa tatgctggaa
    16441 aaagtccagt ctcaactgga acatttaagc aaatctgaac gaaaagtcgc cgatgttatt
    16501 ctggccgccc caggcagatc gattcactta agcattgcca tgctggccca ggaagctaac
    16561 gttagcgagc caacggtgaa ccgtttctgt cgcagcatga atacccgcgg ctttcctgat
    16621 tttaaactgc atctggcgca aagtctggca aatggcaccc cctatgttaa tcgcaatgtg
    16681 gatgaagatg acagcgttga ggcctataca ggaaaaatct tcgagtccgc catggccagt
    16741 ctcgaccatg ttcgtcagtc gctggataaa tcggccgtca accgcgccgt cgatttactg
    16801 acccaggcaa aaaaaatcgc cttttttggt cttggttcct ccgccgcggt cgcgcatgac
    16861 gccatgaata agttttttcg cttcaatgtg ccggtgattt actccgacga tatcgtgctg
    16921 caacggatga gctgtatgaa ttgtaacgat gatgacgtcg tcgtgctcat ttcgcatact
    16981 ggcagaacca agagcctggt ggaactggcg cagttggcgc gggaaaacga tgcgatggtg
    17041 atcgccctga cctccgctgg aacgccgctg gcgcgcgaag ccacgctggc cattaccctc
    17101 gacgtaccgg aagatacaga catttatatg cccatggtct ctcgacttgc tcaactgacc
    17161 gtgatagatg tgctggcaac gggatttact ttgcgtcgcg gggcaaaatt cagagataac
    17221 ttgaagcgtg tcaaggaagc gctcaaggaa tcgcgttttg ataaagaatt actcatcagg
    17281 agtgatgacc gctaaaagca ataacaatgt tctacccttt tcgtcatccg gggacgttca
    17341 ttttataccg ttaaggtttc agaacgaccg gatcaatgtt cacgcaacac caagttgttt
    17401 tagtcaacgg agtattacat gtccagaagg cttcgcagaa ccaaaatcgt taccacgtta
    17461 ggcccggcaa ctgaccgcga taacaacctt gagaaggtta tcgccgcggg cgcaaacgta
    17521 gtacgtatga acttctctca cggctcgccg gaagatcata aaatgcgtgc tgataaagtc
    17581 cgtgagattg ccgccaaatt ggggcgtcat gtggctattt taggcgacct gcaagggcca
    17641 aaaattcgcg tttccacttt taaagaaggc aaagtgttcc tcaatatcgg ggacaaattt
    17701 ctgttagacg ctaacctggg taaaggcgaa ggcgataaag aaaaagtcgg cattgattac
    17761 aaagggttgc cggcagacgt cgttcctggc gatatcctgc tgcttgacga tggtcgagtg
    17821 cagttgaaag tgcttgaagt ccagggcatg aaagtcttta ccgaggtcac cgtcggcggc
    17881 ccgctgtcta acaataaagg cattaacaag ctcggcggcg ggctttctgc tgaagcgctg
    17941 accgaaaaag ataaagccga tattcaaacc gctgcgctga taggcgttga ctatctggca
    18001 gtctccttcc cgcgctgcgg cgaagatctg aactatgcac gccgcctggc gcgcgacgcc
    18061 ggctgtgacg cgaaaattgt ggctaaagtc gaacgcgccg aagcggtatg cgatcaaaac
    18121 gctatggacg atatcattct ggcctctgac gttgtgatgg tcgcacgtgg caacctgggc
    18181 gttgaaatcg gcgatccgga gctggttggt atccagaagg cgctgattcg ccgtgcgcgt
    18241 cagctaaacc gcgcagtcat caccgcaacg cagatgatgg agtcgatgat caccaacccg
    18301 atgccgaccc gtgcggaagt gatggacgtg gcgaacgccg tcctggatgg cacggatgca
    18361 gttatgctgt ctgccgaaac cgcagccggt cagtatcctt ctgaaaccgt tgccgcaatg
    18421 gcgcgcgtct gtctgggcgc agaaaaaatc cccagcatca atgtgtctaa acaccgtctc
    18481 gacgtgcagt tcgacaatgt tgaagaagcc attgccatgt ctgcgatgta tgcggcaaac
    18541 catctgaaag gcgttaccgc gatcatcacc atgacggaat ccggtcgtac cgcgctaatg
    18601 acttcccgta tcagctccgg cctgccgatt ttcgccatgt cgcgccatga acgcacgctg
    18661 aacctgaccg cgctctaccg cggagtaacg ccggtgcatt ttgatagcgc ggctgatggc
    18721 gttgtcgcgg cgcatgaagc tgttaatctg ctgcgcgata aagggtatct ggtttccggt
    18781 gacctggtta tcgtgaccca gggcgatgtc atgagcaccg tcggttcaac caataccacg
    18841 cgtattttga ccgttgagta aagctccccc tggcctgctc atcaggtaat acagggtttg
    18901 tcagcataaa gcctctctta cgagaggctt tatttatttg atgggataaa gatctttacg
    18961 cttatacggc tgaatctcgc ctggcttgcg ggttttgagc aacttcagaa tccaggtgta
    19021 ctgttccgga tgcgggccga caaaaatttc gacctcttcg ttcatccgtc tggcgatagt
    19081 gtggtcgtca gccgtgagca gatcgtccat tggcggacga atctggatag tcaggcgatg
    19141 cgttttacca ttatacaccg ggaaaagcgg tatcacgcgt gcgcggcaca ctttcatcag
    19201 ccgaccaatt gcaggcagcg ttgctttgta tgtcgcaaag aaatcaacga attcactatg
    19261 ctccgggcca tgatcctggt ccggcaggta gtaaccccag tagccctgac gaacagactg
    19321 aataaagggt ttaatcccgt cattgcgcgc atgcaaacgt ccgccaaaac gccgacgcac
    19381 ggtattccag atatagtcaa aaaccggatt accctgatta tgaaacatcg ccgccatttt
    19441 ttgcccctga gaggccatca gcatggctgg aatgtcgacg ccccagccat gcggtacgag
    19501 aaaaataact ttttcgtcgt tacgacgcat ctcctcgata atctccagac cttcccagtc
    19561 aacacgctgt tgaatttttt tcggaccgcg catcgccagc tcagccatca tcgccattgc
    19621 ctgcggcgcg gtggcgaaca tctcatcgac aatcgcttcg cgttcagctt cgctacgctg
    19681 cggaaagcac aatgacagat taattagcgc ccggcgacga gaactcttcc ccagccgtcc
    19741 ggcaaaacgc cccagcgtcg ccagcaaagg gtcgcggaat gatgccggcg ttaatgcgat
    19801 ccccgccatt gccgcagcgc ccaaccaggc gccccaatac tgcggatagc gaaaggattt
    19861 ttcgaattca gggatatact cactattatt ttttttggtt tccatgcttt tccagggtct
    19921 gctgacgcga aaaggaattg tgaatagtgt agcgatgtct gcgccgcaca caaaacaaaa
    19981 cagccggcac acatcgcgta ccggctctgt caacgcattt gttaatcgaa gcgcagttgc
    20041 ggcagaatct ctttcacctg tgccaggtat tcacgacgat ctgaccccgt cagaccttcc
    20101 gtgcgcggca attttgctgt cagagggtta acggcttgct ggttgatcca tacctcataa
    20161 tgcagatgcg gccctgtgga acgcccggtg ttaccagaaa gcgcaatacg atcgccacgt
    20221 ttcacttttt gccccggttt caccagcagc ttacgcaagt gcatgtaacg tgtggtgtag
    20281 gtgcgtccat gacgaatcgc aatgtagtaa ccggcagcgc cgctacgttt agcaaccacg
    20341 acctcgccat cccccaccga cagcaccggc gtaccctgcg gcatcgcaaa gtcaacgcca
    20401 cgatgcggcg caacgcgtcc ggtaaccggg ttcagacgac gcggattgaa gttggaggag
    20461 atgcggaact gtttggcggt cgggaagcgt aaaaagcctt tcgccaggcc aacaccgtta
    20521 cggtcataga atttaccgtc agcggcgcga atggcgtagt aatctttacc atcggaacgc
    20581 atacgcacgc ccaacaactg actctgttca cgcttgccat ccagcatctc acgcgacatc
    20641 agaaccgaaa attcatcgcc ctttttcagc ttccgaaaat ccatctgcca ctgcattgct
    20701 tttatcactg cgctgatttc gctgctggtt aaaccagcct ctttcgcgct ggcgacaaag
    20761 ctgcccccta ccgtgccttt cagcagactg ttgacccagt ccccctgctg catttcactg
    20821 ctcattttaa aaccgttggc agtgcgatcg taggtacgcg tttcacggcg ggagacttcc
    20881 catgtcagac gctgtaaatc gccatcggcg gtcagtgtcc aggaaagctg ttggccaatt
    20941 ttcagattgc gcagctcctt atcagaagcg gcaagtcggc taatatcgct catatcgatg
    21001 ccgtactgat tcagaatact gcttaacgta tcgcctgtgg agacgacgta ttcatggacg
    21061 ccgacttcgc ctgcggtttt atcgtccagc tcatcctgag gaatagcttc atcttcctgc
    21121 gcggcctgat cgatgggttc gctggcctcc ggtaagaggg aacgaatctc gcttttctcc
    21181 agttcaatag ttttaacgat tggcgcggat tctgggtggt aaacataggg ccgccatacg
    21241 gcgacggcca gtgtcagaac ggtaagtgac cccagcataa cgcggtgggg tcggggcaga
    21301 ttattaaatg ccagggcgac agagccggct atctgttgca cgtattcact tcctcgttaa
    21361 tctcctttca ggcagctcgc atactggttg gctaattggc ttaaaaacgc tgaatagctt
    21421 gttttaccca gtttaatgtt cgtcccgagg gggtccagtg ttcccattcg aacggatgtc
    21481 cctctcgcca cggcttccac gaccgctggc ctgaattgtg gctcagcaaa aacgcaggtt
    21541 gctttttgct caaccaactg tgttcttatt tcatgtaaac gctgcgcgcc aggttgtatc
    21601 tcagggttca cggtaaagtg accgagtggg gtgagtccgt agtgtttttc gtagtaaccg
    21661 taggcgtcat gaaaaacgaa ataccctttc cccttgagcg gcgcgagctc gttaccgacc
    21721 tgtttatcgg ttgcggctaa ttgtgcctca aaatccttca ggttggcgtc gagtttagct
    21781 cgactttgcg gcataagttc cactaatttt tcatggattg caaccgctgt agcccgcgct
    21841 atctctgggg agagccaaag atgcatgtta tattcgccgt gatggtgatg tacgtcacct
    21901 ttttcctcat cggcgcccgt atgcgcatgt tcatcctcat catcatccgc gcccttcatg
    21961 agtaacggtt ttacatcggc aagttgcgca atggtaacct gcttattatc agggatattc
    22021 ctgaccgact tctccataaa ggcttccatt tccgggccaa cccagacgac taagtccgcg
    22081 ccctgtaagc gttttacgtc tgatggacgc aatgaataat catgctcgga tgccccatcc
    22141 ggaagtaata cttgcgtatc cgtaacgcca tcagcaatgg cggaagcaat aaacccaagc
    22201 ggtttaagcg aagcgacaac ggcggcgtcg gcagcctggg ttgcactccc ccaaagcgcg
    22261 gcggataatg ctgcgaaaag aagcgtattt ttctgtaaca taatgcgact aatcatcgta
    22321 atgaatatgt gaaatgtgat attataacat tctatcactt ctgcaagcct aaaattaaca
    22381 tgacaagttt agtttcactg gaaaacgtct cggtctcatt tggtcaacgc cgcgtcctct
    22441 ctgacgtgtc gcttgaattg agccccggaa aaattttaac gcttctcggc cctaacggtg
    22501 cggggaagtc aacgcttgta cgcgtggttt taggactggt agcccctgat gaaggggtga
    22561 tcaagcgcaa cgggcaactc cgtatcggct atgtcccgca aaagctctat ctcgatacca
    22621 cgcttccgct gacggtaaac cgatttttac gtttacgtcc ctgcacgcaa aaaacggata
    22681 ttctcccggc gcttaaacgc gttcaggccg gacatttgat tgacgcgccc atgcaaaaac
    22741 tctccggcgg tgagacacag cgcgtactgc tggcccgtgc tctgcttaac aggccgcagt
    22801 tgctggtact tgatgagccg acgcaaggcg tggatgtcaa cggccaggtc gcgttatacg
    22861 accttatcga tcagctgcgc cgtgaactcg attgcgccgt tctgatggtg tcgcatgatc
    22921 tacatctggt catggcaaaa acggatgaag tgttatgcct gaaccatcat atttgctgtt
    22981 ccggcgcgcc ggaagtggtg tctatgcatc cggaatttat ctctatgttt ggcccgcgtg
    23041 gcgcggagca attagggatt tatcgccatc atcataatca tcgccacgat ttacagggtc
    23101 gtattgtact gcgccgggga aatggtcact catgattgaa ttattactgc ccggctggct
    23161 ggccgggatg atgctggcct gcgctgctgg tccgttgggc tcatttgtgg tctggcgtcg
    23221 gatgtcctat tttggcgata cgctggctca cgcgtcgctt ctgggcgtgg cgtttggcct
    23281 gttgctggac gttaacccct tttatgcggt aatcgccgtt acgctgctgc tggcctccgg
    23341 tctggtatgg ctggagaaac gccctcacct cgcgattgat accttactgg gcattatggc
    23401 acacagcgcc ttgtctttag gactggtcgt ggtcagcctg atgtccaacg tccgcgttga
    23461 tttaatggct tatctgtttg gcgatttgct ggccgtgacg ccggaagatc ttatctcgat
    23521 cgctattggg gtcgttattg tgctggccat tctcttctgg cagtggcgca acttgctgtc
    23581 aatgactatc agtccggatc ttgcctttgt cgatggcgtg aagttacagc gcgtgaagct
    23641 gctattgatg ctggtaacgg cgttaaccat tggcgtaacg atgaagtttg tcggagcgct
    23701 gattatcacc tcgctgctga ttatccccgc cgcaaccgcg cgtcgctttg cccgtacgcc
    23761 ggagcagatg gcgggcgtcg ccgttggtgt aggtatgata gcggttacag gtggactgac
    23821 cttctcagcc ttttatgata ccccggcagg gccatccgta gtgctgtgtg ccgcgctgct
    23881 gtttatcttc agtatgatga aaaagcaggc aagctaagcg tgtgttgccc ggtggcgctg
    23941 cgcttaccgg gcctacaaaa tcgcccaggc ctgatgagcg cagcgacttc aggcgttaag
    24001 gcatctctgg cggcgtaata ccaaagtggt tccaggcgcg caccgttgcc atacgcccac
    24061 gcggcgtgcg ctgcaaaaag ccttgctgaa tcagatacgg ctccagcaca tcctcaatgg
    24121 tttcacgctc ttcgccaatc gccgccgcca gattatccag tcccaccggg ccaccgaaga
    24181 atttatcaat aaccgccagc agtagcttgc gatccatata atcaaaccct tccgcatcga
    24241 cgttcagcat atccagcgcc tgcgcggcaa tttccgctga aatagccccg tcatgcttca
    24301 cctcagcaaa atcacgcaca cgtctgagca ggcggttggc tatacgcggc gtaccgcgcg
    24361 cccgacgcgc cacttccagc gcgccgtcat cgctcatctc aagccccatg tgccttgcgc
    24421 tgcgcccgac gatgtgctgc agatcgggca cctggtagaa ctccaggcgc tgcacaatac
    24481 caaaacggtc acgtagcggg gacgttaacg acccggcgcg cgtcgtcgcg ccaatgagcg
    24541 taaacggcgg cagatcgatt ttaattgaac gtgcagccgg cccttcgcca atcataatat
    24601 ccaactggta atcttccatc gccggataga gtacctcttc caccaccggt gaaagccggt
    24661 ggatctcatc aataaacagc acatcatgcg gttcaagatt ggtgagcata gccgccagat
    24721 cgcctgcttt ttccagcacc gggccggacg tggttcggag gttgacgccc atttcattgg
    24781 caacgatatt cgccagagtc gttttaccta accctggcgg gccgaaaatc agcaagtgat
    24841 ctaatgcgtc gccacgccgt tttgccgcct gaataaagat ctccatctgg gagcgcacct
    24901 gcggttggcc gacatattcc gccaataact tcgggcgaat ggcgcgatcg gcgacgtctt
    24961 ctgcgatcgt ggcgcctgct gaaatcaggc gatctgcttc tatcatcctt tacctcatag
    25021 cgcggcgcgt aacgcgtcgc gaatcagtgt ttcactgctt gcgtccggac gggcgatctt
    25081 acttaccatc cgactggctt cttgcggttt ataacccagc gccaccagcg cagcaactgc
    25141 ttcttgttct gcatcttccg aggttgggct ggccggcgac gtcaatacca gatcgaccgc
    25201 tggcgtaaag agatcgccat gtagcccttt aaagcggtct ttcatttcga caatcagcct
    25261 ttcggcggtt ttcttgccga tacccggcag cttcaccagc gcacccagct cttcgcgctc
    25321 aaccgcattc acaaactgct gcgccgacat gccggagagg atcgccagcg ccagcttagg
    25381 cccgacgcca ttcgttttaa ttagctcttt aaatagcgtg cgctcttgct tattgttaaa
    25441 tccgtacagc aactgcgcat cttcacgcac cacgaagtgg gtgaagacga ttgcctcctg
    25501 cccggcctcc ggcagctcgt aaaagcaggt cataggcata tgtacttcat agcctacgcc
    25561 ccctgtctcc agcagcacga tcgggggttg tttttcgaga ataatgcctc tgagtctgcc
    25621 tatcacatga cgctcctgcg taaagggctg aaaagataat gcactatcat aaaaaaagac
    25681 tggatgttta tccagatgaa aaacacttat cccgatattt ctgtactccg acaacccgcg
    25741 atagttaacg acgggcacgc tccccgctgc gtacaaaata agtcgtacac tcattgacaa
    25801 ctttttgcgt cctacgcgaa taactttttg ccaacatgcc gtggcgcaag tttggtagtc
    25861 ttcaataatg agtatcctga taacactaat actgtatcca gtacgaatgc caacagcgga
    25921 acatcggtcc ccccaaaaaa cagacccgag aatagattta ataaaattaa ccactagcgc
    25981 tgaatttaat cgcatgttgt tttatcgtcg cgcacaacat attttaattc accatgacac
    26041 aataaatatt gtgcaaactc atttttcatg ccatcgaaat tcacggctgg tatcccttct
    26101 gaataactat aataaatatt cacatactct tcactattaa aaagtgcctg tcgttttgct
    26161 gctaacccac ggccttttgc tgcaatatac tggaagcagt ggccgctggc accacagctc
    26221 cgcccatcat caacaatata tatatcggca gcgttaaaca actgttccag ccagcactgg
    26281 cgaatcgttc cggccgcaca aaccaaaaat aatgatgcgc taatcatcca cccggatttt
    26341 tttaccgatg tcatagccag gaaagccata aagcacgctg cctgcatgca caaaaccagt
    26401 tctttattcc cggcaaccaa atgccactgg ttaaatacta aggcaatgaa aactgaactc
    26461 aatgttgcca acagtctggt tctgaaccgc ctggcaggga gaagtaaaaa taataatgaa
    26521 atcgtccctg gctttaataa aaaaacaacg gtattagcct ctgccatatc aatactcaaa
    26581 caataacaaa aactaataaa cagatgaaag ataatagcaa caaaaatata agaaaaataa
    26641 aacacccaac ctattttcat tggtttatca tcaaccacgt cgtactccct gtcaatataa
    26701 gagagcagat aatgagaaat ttaccacctt aattcctccc cagttatatt tgcgacatta
    26761 attccaacaa atgaaatatt caccatacat atttcgatga cactaaggct tgtcatttat
    26821 ctggtataat gctaactacc ctgtagaata aataaaagga atttatttca aataatggaa
    26881 tgcagagatg aaaaaacatt atcctgtcca atatgaaacc ggggatatcg tctttacctg
    26941 tataggtgcc gcgcttttcg gccagatatc caccgcttca cagtgctgga gcaaccatgt
    27001 tgggattatt attggtcata atggtgatga ctatctggtg gcggaaagtc gcgtccccct
    27061 ctcaaccgtc accacgctgt cactgtttat acaacgttca gccggacaac gttacgcggt
    27121 tcgtcgcctg tgcggcggcc tgacggtcga gcagaaactc gccatcatgg agcaggttcc
    27181 cgcccggctg aataagtttt atcacacggg gtttaaatac gagtcatcgc gccagttctg
    27241 ctcgaaattt gtgtttgata tctataaaga agcattgtgt attccggtag gcgatattga
    27301 gacattcgaa gaattacttc acagcaatcc tgatgcgaaa ctcaccttct ggaaattctg
    27361 gtttttaggt tcaatcccgt gggatcgtaa gacggtgacg cccgccagcc tgtggcaaca
    27421 tcccaattta gaattaatta gcgcctgtgg aattgaaaac cctcaacgcg aggctgaggg
    27481 agaataattt agcgcaacct tccccgcgcc agattgagtc ggctctcgct catttgcatc
    27541 gcgttctggc taacatggca atgcgtaatg gcgatagcca gcgcatctgc ggcgtctgcc
    27601 tgcgggttag cggggagctt cagcaacgta cgaaccatat gctgtacctg gcttttctcc
    27661 gcgctaccaa taccgacgac agtttgcttc acctgacgcg ccgcgtattc aaacacgggc
    27721 agttcctggt tgaccgcggc gacaatcgct acgccgcgcg cctgtcccag cttgagggct
    27781 gaatcggcat tcttcgccat aaacacttgt tcgatagcaa aatagtccgg ctggaactgc
    27841 gtgatgattt ccgtcacgcc tgcgtatatg agcttcaaac gagacggcaa atcatcgact
    27901 ttggtacgaa tacatccgct gcccagatag gtcagttgtc tgcctacctg gcggataacg
    27961 ccataaccgg taatacgcga gccggggtca ataccgagaa taatcgacac gctatacccc
    28021 ctgcccgccg gcgtttagca gcaccattac agggtcgccg ccacctcatc agagatctca
    28081 ccgttatggt agacttcctg aacatcgtca cagtcttcca gcatatcgat aagacgtagc
    28141 agtttcggcg cggtttccgc atccatatcc gctttggttg acgggatcat ggacacttcg
    28201 gcgctgtccg ctttcagacc cgccgcttcc agcgcgtcac gcactttgcc catctcttcc
    28261 caggcagtgt aaacatcaat cgcgccatca tcataggtca caacatcttc cgcgccagct
    28321 tccagtgcgg cttccatgat ggtgtcttca tcgcctttct caaaggagat gacccctttc
    28381 ttactgaaca ggtacgccac tgagccatcg gtacccagat taccgccgca cttgctgaaa
    28441 gcatgacgca cttccgctac ggtacggtta cggttgtcac tcaaacactc aatcataatg
    28501 gccgtgccgc caggaccata accttcatag atgatggttt ccatgttcga gtcttcatca
    28561 ccacccacac cgcgagcgat ggcacggttc agagtgtcgc gggtcatgtt gttggccagc
    28621 gctttatcta cagccgcgcg cagacgcggg ttggcatccg gatcgccgcc gcccaattta
    28681 gctgccgtta ccagttcacg aataatttta gtgaagattt taccgcgctt ggcatcttgc
    28741 gcagctttac gatgtctggt gttggcccat ttactatgac ctgccataaa tatttcctca
    28801 aaaaaagcgc gccttttcag gcgacgttaa tgacaaactc ttcaatcgct tgccggttac
    28861 tccaggactt ggtaagcgcc gccgcgtcag gcgcatcaag ccactggtac gttagatgtt
    28921 cagtgaatat cacctgccgc tcatgcggta acgcaaggca gaaccagaat tctgtattgt
    28981 gcatgacgcc cggcgcatag cgatgacgta aatgtgaaaa aatttcaaac tccaccgtac
    29041 gttggcagtc gactaaggtc agttgctctg ccgcaacatc aatcgtgacc tcctctttga
    29101 cttcacgcac ggcggtctgc aacgcggtct ccccttcttc tatgctgcca gtcactgact
    29161 gccaaaaatc cgggtcgtcg cgtcgctgca acattagcac ccgtttcgta tcctgcgcga
    29221 aaataaccac caggaccgaa acggggcgct tgtacacttt atccttcacg cgacctcgtt
    29281 gttggctgtt gggtgacgcc gcgcattgat gagactcccc cttgcgggcc gccgcgatat
    29341 cacgcgaatg atgtcgtgta cattgttcat atcagttatt ctcggctttc ttcacaacct
    29401 gaatccccaa ctccgtcaac gctgcctggt tggcgaaact cggcgcttca gtcatcagac
    29461 acgcggcggc ggtcgttttc gggaaggcga taacatcacg aatattgtcg gtgccggtca
    29521 acagcatggt cagacggtcc agaccaaacg ccaggcccac gtgcggcggc gtaccgtatt
    29581 tcaacgcatc caacaggaag ccgaacttct cgcgctgctc ctgctcattg ataccgagaa
    29641 taccaaatac ggtttgctgc atttcaccgt tgtgaatacg caccgaaccg ccacccactt
    29701 catagccgtt aatcaccata tcgtaagcgt tagcgacggc ttcttccggg gcagttttca
    29761 gttcagacgc cgtcatgtca cgcggggcgg tgaacggatg gtgcatcgcg gtcagaccgc
    29821 cttcgccgtc gtcttcgaac atcgggaagt caatcaccca cagcggcgcc catttgtctt
    29881 cgtcggtcag gctcaggtct ttgcccagtt tcagacgcag cgcgcccagc gcatcggcaa
    29941 ccactttttt gttatctgcg ccgaagaaga tcatgtcgcc gtcctgcgcg ccggtacgtt
    30001 caaggatagc ctcgacgatg tcggcggtca ggaacttggc caccggactg ttaatcccgt
    30061 ccagaccttt cgcgcgctcg ttaactttga tatatgccag tcctttcgcg ccgtagatct
    30121 taacaaagtt accgtaatcg tcgatctgct tacggctaag ctgtgcgccg ccaggcacac
    30181 gcagcgctgc cacgcggcct ttcggatcgt tagccgggcc cgcgaagacc gcgaactcta
    30241 ccgatttcag caggtcagcg acatctacca gctccatcgg gttacgcagg tctggcttgt
    30301 cggaaccgta gcgacgttcc gcttcggcaa acgtcatgac cgggaaatcc cccagatcca
    30361 cgcctttcac ttccagccac aaatggcgca ccagcgcttc catcacttcg cgcacctgtg
    30421 gcgcggtcat gaaggaggtc tcgacgtcga tctgagtaaa ctccggctga cggtcagcac
    30481 gtaagtcttc atcacggaag catttgacta tctgatagta acggtcgaaa ccggacatca
    30541 tcaggagctg tttgaacagc tgcggcgact gcggcaacgc atagaattta cctttgtgta
    30601 cgcgggacgg taccaggtaa tcgcgcgcgc cttccggggt cgctttggtc agcatcgggg
    30661 tttcaatatc aaggaaaccg tgatcgtcca taaaacgacg caccaggctg gtaattttgg
    30721 cgcgagtttt caggcgctgc gccatttccg gacgacgcaa atccagatag cggtacttga
    30781 gacgcgcctc ttcggtatta acgtggttag cgtcaagcgg cagtgagtct gcgcggttga
    30841 tgatagtgag agaggacgcc agcacttcaa tttcgccggt cgccatatcc gcattgacgt
    30901 ttttcgcgtc acgcgcacgc acggtgcccg taacctgaat gcagaactca ttacgcagtt
    30961 cagaggccag ctttaacgcg tccgcacgat ccggatcgaa gaacacctgc acaatacctt
    31021 cgcggtcgcg catatcgata aagatcaggc tgccaagatc acgacgacgg ttgacccaac
    31081 cacacagagt cacctgctgc cccacgtggg acagacgtag ctgtccgcaa tattctgtac
    31141 gcatgagata tcccttaact tagccgcagg cggattgttg cctgccatgc aggcgacgaa
    31201 gtcgcagctt tagctgtatg tcacaactgg atgaaaaaag gcggctatta tactggaaat
    31261 tctgccgcac gataagagtc aatccagcat gggagcgata acttgcccgt ttcatgcggt
    31321 atcgacactt ggttcatact gactgtaccc gggtttttca cgcgggtatt gcgtatgctc
    31381 acaaaaatta acaatatttg tcgccgcttt cctctttaat cgcgcttaag gtgtagtgaa
    31441 atccgctatt tttaggagag tgattatcat gctgaaactc aacgcgacca caaccgccct
    31501 ggtggttatt gatttacagg aaggaattct tccgtttgcc ggcggcccgt atacggcaaa
    31561 tgaggtggtc gcccgcgccg cgcggctggc ggaaaagtgt cgcgccaacg gctcgcccgt
    31621 ggttatggta cgcgttggat ggtctgatga ttatgccgaa gcgttaaaac agccggtgga
    31681 tgccgcaacg cctgcgcacg cgttgccgga aaactggtgg acctggccta cggcattggg
    31741 taaaaaggac agcgatctgg aagtgactaa acgccagtgg ggcgcgtttt acggcaccga
    31801 cctggaatta cagcttcgcc gccggggtat cgacaccatc atattgtgcg gaatctcaac
    31861 caatatcggc gtcgaatcca cagcgcgtaa cgcctgggag ttgggattta accttattat
    31921 tgccgaagat gcctgtagcg ccgccagcag tgagcagcat cagagcagta tgacgcatat
    31981 tttcccgcgc attggccggg tacgcagcgt agaggatatt ttaaacgcct tatgatctac
    32041 attggcttgc cgcaatggtc gcacccgaaa tgggcgcggc tcggcatcac cagtctggaa
    32101 gagtatgccc gccactttaa ctgcgtggag ggcaacacca cgctttacgc gctgccgaaa
    32161 gcggaaattg tcgatcgctg gtatgcgcaa actacggacg atttccgttt ttgctttaaa
    32221 tttcccgcca ccatttctca ccaggccgct ctgcgccatt gcgacgatct ggtacaggcg
    32281 ttttttaccc gcctggcgcc gctggaaacg cgtattggcc aatactggct gcagttgccc
    32341 gccgcctttg gaccgcgcga tctccccgcc ttatggcagt ttcttgatgc gctccccgcc
    32401 acgtttacct atggcgtaga agttcgtcat ccgtgttttt ttgacaaggg tgaggatgaa
    32461 cagcggctca atcgcgggtt acacgcgcgc ggcgtaaacc gcgtgatcct ggatagtcgt
    32521 ccggtacatg ccgcccatcc ccacagcgag gccgtccgtg acgcgcagcg aaaaaaaccc
    32581 aaagtcccgg tacatgcggt cgtgacggcc agccatccga tggtgcgttt tatcggtagc
    32641 gataatatgg cgcaaaaccg tgagtttttc gctgcctggt tgcagaaact cccgcagtgg
    32701 cggcagacca ccacgccttt tctgttttta catactccgg atatcgcgca ggcgccggaa
    32761 ctggtgaata cgctttggca tgatttacgc agcgtcttac cggaaatcgg cactgctccg
    32821 tccattccac agcaatcttc tcttttctga aaatgccccc tatcatagac agtgccatca
    32881 gccattttaa aagggagttt gtatggtaag cgcgctgtat gccgttttgg gtgcgttatt
    32941 attaatgaag ttctctttta atgtcgttcg cttacgaatg cagtaccgtg tcgcctatgg
    33001 cgacggcggt tttagcgaat tgcaaagcgc catccgtatt catggcaacg cggtggaata
    33061 tattcctgtc gcgctggtgc tgctgctgtt tatggaaatg aacggcgccg aaacgtggat
    33121 ggtgcatatc tgcggcatca ttttaatcgc cggtcggctg atgcattatt acggttttca
    33181 ccaccgcctg ttccgctggc ggcgggcggg gatgagcgcg acctggtgcg cattgttgct
    33241 gatggtgctg gcaaacctgt ggtatatgcc ctgggagttg gttttctccc tgtattagcg
    33301 cacaatatgc gcctttattt ttcccggatg tatacgttat gtctcaccgc gacacgcttt
    33361 tttctgcgcc tatcgcccgt ctcggcgact ggacttttga tgaacgagta gccgaagttt
    33421 tccccgacat gattcagcgt tcggtaccag gctactccaa catcatctcc atgatcggca
    33481 tgttagctga acgctttgtg cagccgaaca cgcaggtcta cgatctgggc tgctcgctgg
    33541 gtgccgcgac gctgtctgtt cggcgtaata tccgccatga gcattgtcgc attatcgccg
    33601 tcgataactc cccggccatg attgaacgct gccgccgtca tattgatgcg tataaagcgc
    33661 ctacgccggt tgaagtcgtt gaaggcgata tccgcgatat cactattgaa aacgcctcga
    33721 tggtggtgct gaattttacc ctacaattcc ttgaacctgc cgaacgccag gcattgctgg
    33781 ataagattta cctggggttg aatcccggcg gcgcgctggt actgtcggaa aaatttagct
    33841 ttgaagacgc gaaagtgggc gagctgttat tcaacatgca ccacgatttt aaacgcgcta
    33901 atgggtacag cgaactggag atcagccaaa agcgcagtat gctggaaaac gtgatgctca
    33961 ccgactcggt ggaaacacat aaagcgcgcc tgcgtcaggc gggtttcgaa cacagcgaac
    34021 tgtggttcca gtgctttaac ttcgggtcgc ttgtcgcgtt aaaagccgga gttgccgcat
    34081 gatcgagttt ggtaactttt atcagctcat tgctaaaaat catctctccc actggctgga
    34141 aacattgccc gcgcagattg ccgcctggca acgcgagcag cagcatggct tgtttaaaca
    34201 gtggtcgaac gcggtagaat ttttaccgga aattacgccc tggcggctgg atttactgca
    34261 cagcgtcacg gcggaaagcg aaacgccgct cagcgaaggt cagctaaagc gtattgatac
    34321 attgctgcgt aatctgatgc cgtggcgtaa aggcccgttc tcgctttatg gcgtagatat
    34381 tgataccgaa tggcgctcag actggaagtg ggatcgcgta ctgccgcatc tgtcagattt
    34441 aaccggccgg acgatccttg atgtcggctg cggcagcggc tatcacctgt ggcggatgat
    34501 tggcgcgggc gcacatctgg cggtcggcat cgatcctaca cagcttttcc tctgccaatt
    34561 tgaggcggtg cgtaaactgt tgggtaacga tcagcgcgcg catctgctgc cgttgggcat
    34621 tgaacaactc ccggcgctga aagcatttga taccgtcttt tcaatggggg tgctttatca
    34681 ccgtcgctcg ccgctggagc atctgtggca attaaaagat cagttggtca acgagggtga
    34741 gctggtactg gaaacgctgg tcgtcgacgg cgacgaaaat accgtactgg tgccgggtga
    34801 ccgctacgcg cagatgcgta acgtctattt tattccttcc gcgccggcat taaaaaaatg
    34861 gctggaaaaa tgcggctttg ttgatgtgcg tatcgctgac gtttgcgtca ctaccaccga
    34921 agagcagcgc cgtaccgaat ggatggttac cgagtcgctg gccgattttc ttgacccgaa
    34981 cgatcgcagc aagacggtgg aaggctatcc cgccccgcag cgcgcggtgc tgattgcgcg
    35041 taaaccgtga tggattgccg aatgaccgtt acgtatagca ccgtttctcc aaaatagttc
    35101 aagttgcagc aaggcggcaa cgcagcaaat ccccgggaac gtaggtagct acgtgaccgg
    35161 ggtgcgcgag gcggccaacg ctgctgcggc ttgaaatatg aaggagaaaa aaaggcccct
    35221 gttgaattgg caggggcctg gtacgagcaa gcatcatatt gggcgacatg atgcaacggt
    35281 aaaaatcatt tggcctgatg gcgaacaatg attcctttca ttctcagcga ccgccgcacc
    35341 ctctacccta tagcgagaat actcgtccgc ctgtatatcg gcagacatcg ataacccctg
    35401 attgcgatag cgcatcggcg aaggcagtaa gactccggcg gaactgtgta cttcccgtac
    35461 tccggcatcg aggaaattct gcaggttatt tgcacgaacc cccgcaccag ccataatgat
    35521 tggagcatcc ccctgggcaa taagttccat aattattgat aaaccttgcg ccgcatcggc
    35581 tttttgcccg gaagtcagta ctcttgctac gcctgcgtca gccagattct ttagcgcatt
    35641 gaagggatta gcgcacatat cgaaggcgcg gtggaatgtc accgccagcg gcccggccgc
    35701 cgccattatt ttttccattc gcgacatatc gacatcccca tcaacggtca acacgccagt
    35761 aaccagcccg ggaaacccca actctctgac gagacggata tcttccagca tggcggcaaa
    35821 ttcgccgtca gtgtagtaaa aatctccgcc gcgaggacga ataatcggat gtacgggaat
    35881 cgtaatatgc tcgcgtacgc tgcgtaagat gccgaaagaa ggcgtaagcc ccccttcttt
    35941 cggcgcggcg cacagttcga tacgatccgc gccgtttcgc tgcgcggtga gcgcgcattc
    36001 catgctgtaa caacagatct caagtaacgc catattcact ccgctcggca ggttaatggg
    36061 ccgcctgttc gctggcgaca atcgcttcaa tcgaccatgg atgaaatttt accgtgacgc
    36121 ggccatcggt cacagccagc gtagggtttg gcaaacgttc atgctcgccc tgtggcgaac
    36181 tggttttaac cacgatcccc ggctgactaa gcccctcatc cgacaacaac gccagggccc
    36241 tcgcgttcaa ggtctccggc tcgccgggca gcacgatttc aatatgctcc cacccttcgt
    36301 gtggatagcg tttttctccc ggccacggta attcaataac agaaaaccgc cagtgttcca
    36361 cacataccgg ttcatgcagt ttaaacagac aaatcggcct gccgttgatg atattttccg
    36421 acagtagctc gccgcattgt tcaaaaccgc gacgccaacg ctccgccgtc gtattctggt
    36481 gacagcgcaa tgaaatgtga tcggcctcaa gggcgttaat ctgcagacca aggcgagtgg
    36541 aaagttctct gaacgccaga gtgaatcgcg gtaaatctgc ggaaatatca tgcagttcat
    36601 caatgtgttg ccagttcgcc atatcaggac gctcttcttg ctgtgaaaac cgctaattta
    36661 cgctgttgcg ccccggcaac caacctttga tttgattggg cgtttattga atgcttatgc
    36721 agattattgt tgcgtatatt tcaggcgacg cgccgcgcgc gcaatgctga cgccaacggg
    36781 catttgcagt atactcccgc cctaattctt aaactggcgc gggcaataca gtccgcttca
    36841 taaacgtaag gtattccggt gaatattcag gctcttctct cagaaaaagt tagtcaggcc
    36901 atgattgctg caggcgcgcc tgcagattgc gagccccagg ttcgtcagtc agccaaagtt
    36961 cagttcggcg actatcaggc caacggcatg atggcagttg cgaaaaaact gggtatggcc
    37021 ccccgacaac ttgcagagca ggtgctgact catctggatc tcagcggcat cgccagcaag
    37081 gttgaaatcg ccggccctgg ctttatcaat attttcctcg aaccggcttt tctcgctgaa
    37141 caggtgcaac aggcgctgac ctccgatcgt ctgggcgttt ctcagccgac tcgccagacg
    37201 attgtcgtcg actactccgc gcccaacgtc gcgaaagaga tgcacgttgg tcatctacgc
    37261 tccacgatca ttggcgatgc ggcagtgcgc acgctggagt ttctgggcca tcatgttatt
    37321 cgcgctaacc acgtcggcga ctggggcacc cagttcggta tgcttatcgc ttggctggaa
    37381 aaacagcagc aggaaaacgc gggcgacatg gcgctggcgg atctcgaagg attttaccgc
    37441 gatgcgaaaa aacattatga cgaagatgaa acgtttgccg agcgcgcgcg taactacgtc
    37501 gtcaaattgc agagcggtga tacctatttc cgtgagatgt ggcgtaagct ggttgatatc
    37561 acgatgacgc aaaaccagat cacctatgat cgtctgaacg tcactctgac gcgtgacgat
    37621 gtgatgggcg aaagtctgta taatccgatg ctgccgggca tcgtcgccga tctgaaagcc
    37681 aaaggcctgg cggttgaaag cgaaggcgca acggtggttt tccttgatga gtttaaaaac
    37741 aaggaaggcg acccgatggg cgtcattatt cagaagaaag atggcggtta tctgtatacc
    37801 actaccgata tcgcctgcgc caaataccgt tacgaaacgc tgcacgccga ccgcgtgctc
    37861 tactacattg actcccgtca gcaccagcac ctgatgcagg cctggaccat tgtgcgtaaa
    37921 gccggttatg tgccggattc cgttccgctg gaacaccaca tgttcggcat gatgttgggt
    37981 aaagacggta aaccgtttaa aactcgcacg ggcggtacgg tgaaactggc ggacctgctg
    38041 gatgaggcgc tggagcgcgc gcgtcgtctg gtggcggaga agaacccgga tatgccggct
    38101 gacgagctgg aaaaactggc taacgccgtc ggtattggcg cggtgaaata cgccgatctg
    38161 tcaaaaaacc gcaccactga ctatatcttc gactgggata atatgttggc tttcgaaggc
    38221 aataccgcac cttatatgca gtatgcctat acgcgtgtgc tgtctgtttt ccgtaaagcg
    38281 gacatcgacg agcaggcgct ggcgagcgcg ccggttatca ttagcgaaga tcgcgaagcg
    38341 cagctcgctg cccgtctgct gcagtttgaa gaaaccctga cggtggtcgc gcgtgaaggt
    38401 acgccgcacg tcatgtgcgc gtatctgtat gacgtcgccg ggctgttctc cggcttctac
    38461 gagcactgcc ctattctcag cgccgagaat gacgcggttc gcaatagccg cctaaaactg
    38521 gcgcaactga cggcgaagac gctgaaactg ggtctggata cgttgggtat cgaaaccgta
    38581 gaacgcatgt aaacgcgccg tcgttaacat catcaggcct gactccgggt aacggactca
    38641 ggccttttta ttgccacagc ggtatatctg taacaaatca caaggaatga cacatttcta
    38701 tagagagatg gaacatcttt tacctgtgct ggcgctgacc gccccgtatc attaggcggc
    38761 ggattgttca ggtacaggta atgactttta aagactttga tgcggaagag aaactcttcc
    38821 tgagacgtgt gattgtggcg tttggtgtag tggttgtctg ctttggtatc ctgatcttca
    38881 acctctataa cttgcaaatc cgccagcacc actactacac cacccgttcg aatgagaacg
    38941 atatcaagat gctacccgtc gcgcccacgc gcggcatcat ttacgatcgc aacggcattc
    39001 cgctggtgcg taacgtaacc tggtatgata tcgcggttac gccctataaa attgccgata
    39061 tggatgcgct gctaaaacag ctcaccccta ttgttgatct ctcccccgac gatatcgccg
    39121 actttcgccg cgcgctaaaa tccagtagcc gctatcgtcc ggtagtgctc aaaaacgcgc
    39181 taacggatgt tgaaatcgca cgctttgcgg tcaatcagtt tcatttcaac ggcgtcacga
    39241 tcaatagcta tcaggatcgg cagtatcctt acggcgcgga gctggcgcat gttctcggtt
    39301 acgtgtcaaa gataaacgat aacgacctta aagcgctgga taaaaaaggg ctggcagaga
    39361 attacgcggc ggaccataac atcggtaaac aggggattga gcgttactac gaaaacgatc
    39421 ttcatggcaa aaccggttat caggaggtcg aggtggataa tcacgggcgt attgtccgcc
    39481 tgctgaaaga cgttcctccc atcgcgggta agaacattca cctgacgttg gatctccatt
    39541 tacaagagta cattgaaagt ttgctggccg ggcagcgtgc tgccgtactg gttgaagatc
    39601 cgcacgatgg ttcagtgcta gcgatggtat ctatgcccag ctacgacccg aacccctttg
    39661 taaaaggcat tagctatcag gattacggca aactgctgca cgataaaaat ctgccgctga
    39721 tcaaccgcgt gacgcaaggg ctttatcccc cggcgtcaac ggttaaaccc tatatggcga
    39781 tgtccgcgct gttatgcggg attattacgc cgcaaaccac cttctttggc gcgccaacct
    39841 ggacgcttcc cggcacgcag cgtcattacc gggactggaa aaaaaccgga cacggtatgc
    39901 tggatgtcac taaagcgatt gaggaatctg cggatacctt tttctattag gtcgcttata
    39961 tgatgggtat tgaccgtatc gacacgatgt tgtctcagtt cggctatggc aaaccgacgg
    40021 gtatcgacct tagtgaagag tatgacgggc tgcttcccag ccgcgcatgg aaacagcggg
    40081 tccataaaaa agcctggtat cagggcgata ccatctctgt cggcatcggc cagggctact
    40141 ggattgccac ccccatccag atggtaaaag cgatggtggc gctcatcaac aacagtaagg
    40201 tgattgcccc tcacctgtta ctcaatgaag agagcggcaa aacggtggtt ccgtatcgtc
    40261 cttcaggaac accggcacag atagccgatc cggcgtcgcc atactgggga ctggtgcgtc
    40321 aggcgatgta cggcatggcg aatgcaccca acggaacggg ctataagttc tttcacaccg
    40381 cgccctacgg cattgcggcc aaaagcggca cgtcgcaggt gtttagcctg aaagaaaatc
    40441 agacctacaa tgcgaaaatg atccccattc gcctgcgcga tcatgtgttt tataccgctt
    40501 ttgcaccgta taaaaaccct aaggtcgcta ttgccttgat tctggaaaac ggcggaagcg
    40561 acggcgttac cgccgcgccc atcatgcgaa aaatccttga ccacctgttt gatccacagg
    40621 ctgataccac acagtcgggt caggcgccat agtcaaataa gcaaagcgcc atcagacaag
    40681 gatacgaccg gaatatctgc atacatcaga aatagttacg cagatattcc gtcaaacaca
    40741 gcattgccat cgcctgcccg taaggcatag aggtcaacgg aatatgacgg taaaaatcga
    40801 gatcgtggcc catgccagtg ccaaatgatg tttgcagcag ttcgccttcc ggcgagatat
    40861 gtttcactat cccccgaata gctttttccg ccacctgcgc atagtgccgt tcgacatagc
    40921 gtttgcgcac cgctttaaga ataccgtagg caaaacccgc cgtcgccgac gcctcaagat
    40981 aagagtgcgg atcgtcaagc agcgtatgcc acaaaccgct ttcatcctga catttcgcca
    41041 gcgcggcgat ctgcgcattc agtacctgga ccagataacg gcgcacggca ttattttccg
    41101 gcaagtccag cagttcaaga aaatccggga ccacaatggt cagccagctg ttgccgcgcg
    41161 cccagcgagc gttagcgaag ttatgatgac cgtcatagct ccagccgtgg aaccacagcc
    41221 ccgtctcttt atccatcaaa ttctgcacgt gtagcaggaa ctgataggtt gcctcttcca
    41281 catattccgg ccggttcaac agcttaccga ttttcgccag cggcagcacc gtcatcatta
    41341 gcgtgtcgtc ccacatctgc tgatgatttt cctccgccag cgtgatgtgc tgcattccgc
    41401 cgtaatcggt acggggcatt tcattcatcg cccattcggc ccacgtttcc agccacggta
    41461 aatacgctgg attacgcgtc tcttcatagc gatacgccag cgttaaaaac ggcgccatcg
    41521 tattaacgtt tttcgtcgtc gcgccttccg caaagcgatc ggcaaaccag tcatcaatga
    41581 tcttacgcat cgtctggtcg ccggtctgtt ggtaatagtg atacattccg tacaggccca
    41641 cgccgtgcgt ccactcccat ccggcccagc ctttagtatc gatcacgcgt ccgtcgtcca
    41701 gtcgcaataa aaattcgcct gtctcatctt taatattgac caggttatgc gtcacctttt
    41761 gcaccagggc ttttagttca tctctggcga taaaatgctc aggctgacgc aatagcggac
    41821 tgtgtttgac tggataaacc atcatttgct taacctctgt gtaatgtcga attcagtgct
    41881 gcgtgcagtt ttaccgccga cgcagtcgat tcgctacagt aaaagctaag ctgggcggaa
    41941 acctttttgt ttctgccatt gtcagagcgt aaatggcaaa aacgcaaaga gtccggcaac
    42001 ctacctcacc attttataaa acgacgtttc tatttattca aaaagagagt caggtctgct
    42061 acctggcaaa gaaaggggcg gttagcggta gttcacaatc acctgattgc tccgcacttt
    42121 taacgccggg ataagtctgc cgccgccggg gacttcccag acaaagcgga gcggctcgac
    42181 tgcgggaaca tgagcaaaac cgtgggtcgt gccactctga ccatcaagtt ctacgcaacg
    42241 ggactgggaa cataaacgta cccgtaatcc tgcgggggtc gggccattca gttcataacg
    42301 ccaggcgacc agcgtcatca caccggaaac cggctggcgc gccgacaatg gcgaagacga
    42361 tgcggaaacg ccccggtaat ttaaggttac gcccataccg ctatcctgcc acgcgccttc
    42421 gcctgcggcc tgaaccgtta ggggaaagag caacaatgcc agccatttac gcattatttt
    42481 cctccaatgg tcgccgtcat gcggatatga cggttatcgg aaagctcaag gttcgacaac
    42541 accaccagct gcggtaaact gcgccgcaaa aagcgggaca ataatggacg tagcgcatgg
    42601 ttaaccagta ataccggcgg cgcgccaagc atttcctggc gagaaagtgc ctcttgggtc
    42661 tgcgccagca ggcgatccgc caacccaggc tcaagtccac cgccgccctg caatgcctga
    42721 agcagcaaac gctccagcgc ggtatccagg ccaatcacct gcacttcttc attaccgggg
    42781 aaccactgtt gcgtaatcgc tcgccctaat gccacgcgta ccacggcggt taattcatgc
    42841 ggatcgcttt gtaacggcgc atgttccgcc agcgtttcca gaatggtgcg catatcgcga
    42901 atagggactt tttccgccag taagttttgc aggactttgt gtaaagtcgt gagggtcacg
    42961 acgccgggga ccagatcttc cgtgagttta ggcatctcct gagagacacg atccaacagt
    43021 tgctgcgctt cctggcggcc aaacagttcg gcggagaatt ggccaatcaa gtggttaagg
    43081 tgcgtcgcca caacggtact ggcttccacg acggtaaagc cctgaatttg cgcctgctct
    43141 ttcagggcgc tttcaatcca gatggcatca aggccaaaag ctggatcgac ggttttctcg
    43201 cccggtagcg ttcccgccgc cgtgccgggg ttaatagcca gccagcgtcc cggataggcg
    43261 tccccgctgc cgatctctac ccctttcatc aaaatacggt agcgcgcagg ctgtaaatcc
    43321 atattgtcgc gaatgtggac caccggcggc aggaacccca tatcctgcgc gaatttttta
    43381 cgaatactgc gaatacgtcc gagcaattcg ccatcctgtt gaaaatccac catcgggatc
    43441 aggcggtagc ccacttccat tcccagtgaa tcctcaagct gtacgtcatt ccaggtggct
    43501 tcgaccaccg agttattttc cggcattttt accggctgcg gctcctccgg cgctttttct
    43561 tcacgcccgc gcagccacca tgccaggccg agcaaagcgg cggtaaagag taaaaatacc
    43621 aggttaggca ttccaggcac catgccaagc agccccagca ccgccgccgc cagcagcatt
    43681 acccttggat tactgaacag ttggccaacc atctgctcgc ctacatcctg atcggtactg
    43741 acgcgggtca caatgacgcc cgccgccgtg gagataacca gcgccgggat ctgggcgacc
    43801 aggccgtcgc caatggtcag cagggtgtag ctttccgccg cgctgcccat gctcattccg
    43861 tgctgtaata cgccgaccag cagcccgcct accacgttaa tgaccatgat gagaataccg
    43921 gcgatggcgt cgccgcgtac aaatttactt gccccgtcca tcgaaccgta gaagtcggct
    43981 tcctgagtga cttccgaacg ccgttttttg gcctcgtctt caccaatcag accggcatta
    44041 agatcggcgt caatcgccat ttgcttaccg ggcataccat ccagcacaaa gcgcgcgccg
    44101 acttcggcaa tacgtccggc acctttggtg atgaccatga agttgataat gacgaggatg
    44161 ataaaaacca caatcccgat cgcgaagtta ccgccgacca ggaaatgacc gaacgcctct
    44221 accacctttc ccgccgccgc cgcgccggta tgcccttcca tcaaaataat gcgcgttgag
    44281 gcaacgttaa gcgccagacg cagtagcgtg gtaaacagca ggatggtcgg aaacgcggca
    44341 aaatccagag tacgctgggt aaacatcgcc accagcagca ccatgatcga tagcgcaata
    44401 ttaaaggtaa acaataagtc gaggataaaa gcaggtagcg gcagcaccat catcgacaaa
    44461 atcagcagaa tgaggatcgg cccggcaaga atttgccatt gcgtcgattt caggttgctg
    44521 ggcaggcgca gcatcgcgac cagattagcc atcagtattc ttctcgttca taaaatccag
    44581 cgcttctggc accggaaggt tctcaggttg tggaggacgt tgcccgcccg caagccgcca
    44641 gcgtttaagc tgccagaccc aggccaacac ttccgcaacg gcagcatata actgcccggg
    44701 aatttgctga ccgatttcgg cgtggcgata taatgcccgc gccagcggcg gcgcttctaa
    44761 agtgggaacc cgatgttcag cgccgatctc gcgaatgcgc agcgctatta atccagcccc
    44821 cttcgcgacc actttcggcg cgctcatttt gttttcgtca tactgcagcg ccacggaata
    44881 gtgcgtcggg ttagtgacaa tgacgtccgc tttcggcaca tcttccatca tgcggcgctg
    44941 cgcggcggcg cgttgcatct ggcgaatttt gcccttaaca tgcggatcgc cttcgctctc
    45001 tttaaattcg tcgcgaatgt cctgccgcga catgcgtaat tttttcaggt ggctaaagat
    45061 ctggaaaaaa acgtcaaatc ccaccatcgg gatcacgccc agtaccacca gtaacgcgca
    45121 gagtccaacc agatccagcg cattccccat tgcgacgatc ggcgactccg ccatcaggcg
    45181 catcatttgc ggccagtgat tccagagata aaagccggta acgcagccga ccagcgtgga
    45241 tttcaacacc gcttttagca gttccgcgcc ggtctgcgcc gaaaacatgc gcttaattcc
    45301 cggcagcggg tttaatttag aaaattttgg ctgtagcgac ttaccgctaa aaatcaggcc
    45361 gccaagcata accggcgaga taagcgccac cagcaccacg cccgcgatga gcggtagcag
    45421 tgccatcatc gccgctttaa tcagcaaaat tatctgcccc aggatcaggt taggatcgtt
    45481 caccatacgg tgatcgaagt gcaggcctgc tgagagcatt cccgccagct gccgcgctaa
    45541 cgactcgccg ccgaaccaaa taatacaaac gcccaccagc aatatcagca gtgaggtcag
    45601 ttctctggaa cgggggatct gcccttcttc ccgcgctttt tcaagtcggt ggggtgtggg
    45661 ggcttctgtt ttgtcgtcgt cgctctcttc tgccacgcag caaaccctgg atagattgat
    45721 aagcgagaat gatgccagaa ccgctttacg ccaatgggca gagtaagcgg taaaaaaggc
    45781 ggggtttatg gcgttaatag agatagccgg atacgataag aaagtatcgt atccggccgg
    45841 gttgacggat tcggacccga taagcgcagc gccatcaggt caaaaaagct taaaagccaa
    45901 gactgtccag caggtcgtcc acctgctcct gactggcgac gacgccagct ttcgaggtat
    45961 ccacctgcgg gccgttgagc aagctttcgt tctcgcgttt tggtcgcgcg ctctgttccg
    46021 ggatgttttc cagcagcacc attaacaact ggcgctcaat ctcctgaatc acgtccatca
    46081 tgcgtttgat cacctgaccc gtcagatcct ggaaatcctg cgccatcatg atgtccagca
    46141 gttgcgcgtt agtaaagctg gtatggcccg ggacatccct gagaaactgg cgcgtatccg
    46201 tcaccagttc acgggcgtcg gaaagctcga tcggattgtc aagccactcg tcccaacgtt
    46261 gggttagcgc tttcgcctct ttttccatcg catcctgatg cggctgcgag gcttcgacac
    46321 tgtttagcgc gcgttccgcc gcctgcgccg tcatctggac gacataatcc agacggtcgc
    46381 gcgcatcagg gatcgcctcc gccgcttcgg caatcgcctg gtccagcccc agttcacgca
    46441 ggctgtcgcg cagcattcgg gtcagactac cgatgcgcgc aatgatgtct cctgctgagc
    46501 cttcatcagc aggcttgata gatggttgca tcatcatcgc atcctcacat gcccagtttc
    46561 tcaaagattt tgttgagctt ctcttccaga gtcgctgcgg tgaacggttt tacgacataa
    46621 ccgctggcgc cagcctgtgc ggcggcgata atattctctt tcttggcttc cgccgtgacc
    46681 atcaacacgg gtaacgccga catggcgcta tcggcgcgaa tggttttcag cagctccagg
    46741 ccatccatgt tcggcatgtt ccagtcagag ataataaaac caaagccgcc tgcctggagc
    46801 ttgttcagcg catcgacgcc gtcttcggcc tcttccacat tgttaaatcc aagctctttt
    46861 aagaggttgc gcacgatacg acgcatggtc gaaaagtcat ccacaaccaa aaatttaagc
    46921 tctttatccg ccataaaata ctactcctgg ttcaaatacg tatcgcctgt ccggcactga
    46981 ttttcgccag catctgctgg cttacctggc taagatcgac cacttcgctt acgccaccca
    47041 tattgatggc ctcgcgcggc atgccgaaca ccacacaact tgcttcgttt tgcgcaatgg
    47101 tccaggcgcc agcctggtac atcgctaaca ttccagcggc gccatcgttg cccatccccg
    47161 taagaatgac gcctacggcg ttgcgccccg cgtgtttcgc caccgaatga aacagcacat
    47221 ccacggaagg ccgatgccgg tttaccggcg ggccatcatg aattttgatt tgataattcg
    47281 ccccgctacg cgccagctcc atatgcttgt cgccgggcgc aatgtaggca tgacctggca
    47341 atacgcgttc gccgtcctcc gcctccttca cgctgatttg acagagttta ttcaggcgct
    47401 cggcaaacga gcgggtaaag ccaggcggca tatgctgcgt aataatcact gccggactgg
    47461 aaagcggcag cggttgcagc acatgtcgga tagcttcagt accgcccgtt gaagcgccga
    47521 tagcaatcag tttttccgaa ctgagcagcg gaccggcttt taaggttgtc ggggccgcca
    47581 tcggtttatg tgcggcgatg cgggcccgcg cggcggtacg cactttttcg gcaatcatct
    47641 cgctatacgc cagcatacct tcacgaatgc caagctgcgg tttggtgaca aaatcgatgg
    47701 cccccaactc cagcgcccgt agcgtcactt cggaaccttt cccggtcagc gaagagacca
    47761 tcaccaccgg catcggtcgc aggcgcatca gtttttccag aaaatcgagg ccgtccatac
    47821 gcggcatctc aacgtccaag gtcaatacgt ccggattaaa ttttttgatg agatccctgg
    47881 cgaccaacgg gtccggcgca gtcgctacca tctccatatc gctatggcta ttaataattt
    47941 cagtcatgat ttggcgcatt agcgcggaat catcaactga caataccctg attttactca
    48001 tgctttatcc ttacttagcg catacaccgt ctgtccgcgc aggctaaact cgcgcacgag
    48061 gttgctaaag ttttctgagt gaccggcaaa caacagtccg tcaggtttaa ggagtggaac
    48121 aaaacggcgc agaatgtcct cctgagtcgt tttatcaaaa tagatcatga cgttacggca
    48181 aaaaatcgcg tcaaagggac cgggtacgtt gtactgcttt tccaataaat taacggagga
    48241 aaattcaaca taattggcca gttgctgacg cacgcgcacc agtccttcat gcggccccgt
    48301 accgcgcatg aagtaacgtt gtagctgctg cggcgataac gttttcagtt cgctgaggcg
    48361 ataaataccg cttctcgctt tttccagcac ttcagtatca atatcgctgg cgaatacttt
    48421 ccagcgaccg ggggccatcc ctaacgcatc cgccagcgta atggcgatac tgtaaggttc
    48481 ttctcctgtc gatgccgccg cactccagac gcggtattcg ccgtggcggc gacgcgcatg
    48541 ttccgcaagg atgggaaaat ggtgcgcctc gcgaaaaaaa gcggtcaggt tggtagtcag
    48601 agcgttgata aaagcctgcc actcaacgct gttttgatta gcctccagca tactgagata
    48661 acggccaaaa tcatccagtc ccagggcacg cagccgacgg accaggcggt tataaaccat
    48721 atcccgctta tggtcggcca gcacgatccc tgcacgctgg tagattaatt gacatatccg
    48781 acgaaaatgc gcgtcggaca gcgcgaggcg ctgtgtcatc tgtaacaata ctgacgtttg
    48841 cccggagggc agagatgatg tcatagcgcc ttcttaatca cattcaaagt acaacgggcg
    48901 cgccctgcgg cagcgccatg cttcccgtat tacacatttt ttgcttttat ctatgcgaac
    48961 cagacgaaag ggatcggcgg gttcgcaaat taatcgataa ccgacagcac acagcgcaca
    49021 tcgatcagaa ggtttcccag ttcgcatcat ccccggcggc taagggccgc ggcgtattgc
    49081 cggactgagc gtccactgat aaacgcatct caggtttatt taccgccagc ggtcgcgatg
    49141 ccaggcggaa agccgatacc gcctgggtca gacggctggc ctgctcttcc agcgcggcgg
    49201 cggccgctgc ggattcctga accagcgagg cgttctgttg cgttacgcga tccatttcgg
    49261 aaacggccaa agcgacctga tcgatacccc ggctttgctc atccgaggcg gaggcgattt
    49321 cgcccatgat atccgtgacg cgcgtaacgg cattgacgat gtcagtcatg gtttccccgg
    49381 cgctttccac cagcactgaa ccggtatcga cacgcgagac ggaatcttca atcaacgctt
    49441 ttatttcttt cgccgcctgg gcactgcggc tggccagatt acgcacctcg cctgccacga
    49501 ccgcaaaacc gcgcccctgc tctcccgcgc gcgccgcttc taccgccgcg ttcagcgcca
    49561 gaatgttagt ctggaaggca ataccgtcga taacgctgat aatatcagcg atttttttcg
    49621 aactgtcggc aatttcgtgc atagtgttta ctacgccgtc gaccactttg ccgccatgac
    49681 gcgcggtctc ggaggcgctt tgcgccagtt gcgaagcctg acgggcatta tcggcgtttt
    49741 gcttcacggt ggccgtcagt tgttccatgc tggccgccgt ctcctccaga gcggaggctt
    49801 gttgttcggt acgggaagag aggtcggtat taccggcggc aatttcactg gtgccggaat
    49861 aaatcgcatc cgaaccttca caaacctgcg tcacggtgtc aatcagcgag cgttgcatat
    49921 gttcaaccgt tcccaccagt tcgccaattt cattacgtcc tgagacggtg agcgttttcg
    49981 tcagatcgcc gctggcaatt tcacggatat gagtaatcac tcgcgctaat gggttaagca
    50041 aggcatgacg aatgccgaac caaaccacca tcaaaatcag caccagcacg accgcaagaa
    50101 cccccagttg ccattgcgca aaacggtagt catgagcact ttgatcaaat gtctggcggt
    50161 acaggttttc gctcacccgg gcgtaattgc ccagcgcctc gcccaacgcg ttttgcattc
    50221 cctgggttgg ctgggcgaag taggcatcca tattgccatt gtccagaaac tgaataagtt
    50281 cggctaatgc ggcctgatag cgctgatatt tttcatcgac gttcgcgctg gcctccgcca
    50341 tcgctggcaa tggcgtcatg tttttgaaat tggcgtagtg cgccgccgcc tgtgcgaggg
    50401 tcgtttttgc attctggagt aaatccgttt tggcgctgct ctgctggtta gaagcgtcca
    50461 tcatcatgcg tgcggcggag cggctcaggt taatgcgcgt ttgcagcatt aagtcccatg
    50521 tcgacgtgag ttcgctttgt tgctggcgta attcgttaga aataacaaaa ccttgctggt
    50581 tatgctgtaa tgaagaaaac agcaaaccac cggaaacaag ctgtagcagt gcgaaaaccc
    50641 ccagcaccat catcagcatt gtgacaacgc ggatacggtt aaacataagg caccttcctg
    50701 ataacgagtt atcaacgtta tcggcacctg cggtgataac tttacttttg caaaaaggaa
    50761 atacgctgtt ccggaagacg acattgccaa tgacagtgtc gcagcggcga tgccggcgca
    50821 aaatgcaggg gctgggcgcg ggcgatgaag aggcactctc accgctggcg gaagcataac
    50881 ggtgaatatt gccggatggc gcgacgccat ccggcaacgt tattacgcga cgtgtgatgc
    50941 tgcgatatcc agcagcgcca tctcttcgct gttaagcagt ttttcgatat tcaccagaat
    51001 cagcatacgc tcgccgagcg cgcccaatcc cgtcaaatat tctgttgaca aggtcacggc
    51061 aaattctggc gccggacgga tctgttccgc cgttaacgac agtacgtcag acacgccgcc
    51121 taccactatc ccgacgacac gttgccccag attcagtacg atcactaccg tattgtcatc
    51181 atactcaacg tcgccttcgc agaatttcac gcgcagatcg acaatgggga caatcacgcc
    51241 gcgcaggtta gtcacccctt ttataaaggc cggtgtattg gcgatgcgcg tcacctggtc
    51301 atagccacgg atctcctgca ctttcaggat atcgatgccg tactcttcat ttcccagtgt
    51361 aaacaccagg aattcctgac ctgacggctc gccggccagt ttgcttacat tactcatacc
    51421 ggtcatatta ttcccttctc actcaatcag gcggctgtga tcgccatacg ttgttcgcgg
    51481 tttaaaccct gcaatgcgga aacatcaaca atcagcgcga cgctgccgtc gcccaggatc
    51541 gtcgcggcgg aaatccccgg taccttgcga taattgcttt ccagattttt gaccaccacc
    51601 tggtgctgac cgatgagctg atcgaccagc agcgcgtaac ggcgtcccgc gctttgcagg
    51661 atcacaacaa tgccctgcgt ggattcggtt ttcgccccgt ccacgtcaaa cactttccac
    51721 aattcgacca gcggcaaata ctcgccgcga acttccagaa cccgttcgcc gcccgccagc
    51781 ggatgaagat cctcttcacg cggttgcagc gactccatca ccgcatttaa cggcaggata
    51841 aaaacttccc ccgccacgcg aaccgacatc ccatcgagga tggccagcgt cagcggcagc
    51901 agaatacgaa tcgtggtgcc ggagccttgt tttgactgga tctcaacgtg accgcccatc
    51961 tcctgaatgt tacgtttcac cacatccatg ccaacgccgc gaccggagac atccgtgacc
    52021 tgttccgcag ttgagaatcc cggcgcgaag atcaacatgc ctacttcatc gtcggtcatg
    52081 ttttcattca ccgccatccc ctgcgacatg gccttcgcca ggatacgctc acggttaagc
    52141 cccgcgccgt catcggtcac ttcaatacaa atattcccgc cctgatgttc tgcagaaagg
    52201 atcagattgc cgacaacatt tttccccgcc tcaaggcgtt tttccggcat ttcaatcccg
    52261 tggtcgagac tgttgcgcac caggtgcgtc agcgggtcga taatgcgttc gatcaggctt
    52321 ttatcaagtt cagtggagct ccccaccagc gtcagctcta cctgcttgcc cagtttgccc
    52381 gctaaatcgc gtaccagacg cgggaaacgg ctgaagacgt actccatagg catcatacga
    52441 atcgacatca ccgactcttg taagtcgcgg gcgttacgtt gtaactgccc catactggta
    52501 atgagatcgc cgtggtttac cgggtccagc tcgttagaac gctgggccaa cattgactgg
    52561 gtaatcacta actcgccgac caggtttatg agctgatcca ctttctctac cgccacgcga
    52621 atgctggtgg actcgcgttc acgcgcaggt ttttcacgcc ccgcatgatg ttcatgggcc
    52681 gcgcttttgg cggctggcgc aacgactgcc ggagacgcta ccggtgctac ctcggttttc
    52741 tcttgcgctt tttcaaccgg cgcggtgacc actttttcaa aagcgatctg atcggcctcg
    52801 atgacaaaac agagcaccgc gacaatgtca tcttccgcga cgctgccatc cagagttgcc
    52861 gacagtgaat ccgccccctt aacgacatcc gtcagagtag ccagattgcc caactcttct
    52921 tcaagcagat cgacctcatt ggctttcaac cgtgaaagta caatgcgcag tttactctcg
    52981 tcacgaggcg attcggtttc ggctacgctc tcttcctgga tcgccgcact tagtgccgcg
    53041 gtttctacga ccgccggcgt ggtttcgcct ttcgcctcca gcgccaactg gcgtagcgca
    53101 ttgcagatat attcgaagct tgcggcatcc ggctcttcgg agtttttata ggcgtcgagc
    53161 tgttcctgca taatatcttt cgtttccaaa aacaggttga taatgtcggt attgagctgc
    53221 atttcaccgc gtcgggcttc atccagcagg ttttccatta aatgtgtggt ttcctgcaga
    53281 atagtgaagc cgaatgtgcc cgcgccgcct ttaatggagt gcgccgcgcg aaaaatggcg
    53341 ttcagttgtt cagcgtccgg ggattccggc accaaatcca gcagatgctg ctccatatca
    53401 gccaacagct cgtcagcttc atcaaaaaat gtctgataaa aatcgctaat atccatgctc
    53461 acgctatcac ctcggttccg cttttggcga tgtgggtacg cttgccggcg gggctgccgc
    53521 aggctgttgt aatacactta ccggctcatt ctggctttca gcgttttcat gcaaaatggc
    53581 ctgttccgcc tgtttgttta acaccagcag gcttatacgg cggttgatgg cgtcatcagg
    53641 accgcgatcg ctcagccgca tcgtggcggc catgccaacc acccgtaata cttttccgtt
    53701 atccagcccg ccagcgacca gttcgcgacg agaggcattg gcgcgatcgg cggataactc
    53761 ccagttgcta tagccttttt cgccgttcgc gtagggaaag tcatcggtat ggccggccag
    53821 gctaatgcga ttaggtatac cgtttaacac tggcgcaatc gcacgcagga tatcgcgcat
    53881 atacggctca acttcggcgc tgccggtttt aaacatcggg cggttctggc tgtcgataat
    53941 ctggatgcgc aacccctcct gaactaaatc aattttcaga tgcggacgta acgcgcgcag
    54001 tttgggatcg gattcgatca gttgatccag atcgccgcgc agtttgttta accgactctg
    54061 ctccatccgt tttttcagct cgtcgatatt cggctgcttt tccacttcac cctgctgttg
    54121 ggtgtaatca tcgccgccgc ctggtatcgg gctcttgcta ttggcaatcc gatttccccc
    54181 cgttaccgcg gtggccaacg gcgtacgaaa atattcggca atctgaatta attctttagg
    54241 gctggagatg gaaatcagcc acatcaccag aaaaaaagcc atcatcgccg tcataaaatc
    54301 ggcgtaggca attttccagg aaccgtgcgc cccgccgccg tgcggtttgt gcctgcggcg
    54361 ttttacgacg acaatgggat gagcctgatt tttcatgctt cctcagtcgt ctgctgctgg
    54421 tttgggtttc tcactgcgcg aacgtgttct tccaactcaa taaacgatgg acgctcactg
    54481 gaataaagcg ttttacgacc aaattccacg gcaatcggcg gcgcatagcc gttcagatta
    54541 gacagcagtg taatttttac gcactgcatc atcttagtgg tttcggcgct cttctggcgc
    54601 aaaacggtcg ctaacggtga aatgaatcca taagccagta aaataccgag gaacgtacct
    54661 accatggcat gggcaatcag cgcccccaac tccgctgccg gacgatcggc tgaagccaga
    54721 gcgtgaacca cccccattac cgccgcgacg ataccaaagg caggcagcga atcccccacc
    54781 atcgccagac tgttggccgg gacttccgcc tcgctttcat gggtttcaat ctcttcatcc
    54841 atcaacgctt caatttcgaa cgtattcatg ttgccgctga tgatcagacg cagataatcg
    54901 acaataaaat caagcattac cgcatcggcc agaatacgcg gataactggc gaagatttca
    54961 ctctctttcg gattttcaat atcgcgttca agggagaaca tcccctgctg gcgtgatttg
    55021 gccatcaggc gatagagcaa cgccagcaaa tccatgtaca tagatttcgt gtatttcgaa
    55081 cggcgaaata acaacgggat cgctttcatc gtgcctttga tggccttccc gttgttgccg
    55141 acaatgaacg cccccatccc cgcgccgcca atgatgacca gttcagcagg ttgatagagt
    55201 gccccaaggt gtccgccggt catgacataa ccgccgaaaa ctgtaccgat aaccaccaag
    55261 taacctaata agataagcac gacatcatcc ttccgctgtt gactatgaca ggatgcgcag
    55321 tcgggcgatt aacgcgaagg caaggcaaaa aaaaaaagca gcggtaatgg cttaccgctg
    55381 ctggagtgtt tgtccacacc gtttcggtta aacagcctgt tcgatctgtt catccagcag
    55441 ttgtggaata atatcggcag catctcggga aagtttacgt ctttttactg cgcgggatgg
    55501 cggctggcat aaactacacg caaagctgcc tacgggctga tgcgcatggg taataaagtt
    55561 cccaccgcag cagttacagc tcgacaattc aagcaaccca ctttcaacaa aacgcaccag
    55621 cgtccatgcg cgagtcagcg ccaacaacga cccttcaggc ggttgcggac actgctcaag
    55681 ataaagccga taagctttaa tcaccgcatc cacaccgctg cataagccgg tcttcagtaa
    55741 aaattgccag gcgttgcaga acatggaggc atgaatattt tgctcccagg tcataaacca
    55801 gtctgtcgaa aatggcagca tccctttagg cggcgggcta ccgcgtaatt ctttgtacag
    55861 cctgatgagg cgaccacggc tgagctgtgt ttcgctttcc agcatttgta gacgagcgcc
    55921 aagattaatc aactccatcg ccaactggat atcgcgagct tcctgaacaa tgcttttttc
    55981 gctcattatc atgccctttt cttacgcgcc gtatcgtcca cttcattgag cagacgcgtt
    56041 gaaagcatga tacctgtgtg aatctgctgt aagtcatcga cgcgcgaatc ctgagtcaaa
    56101 cgggtgatcg tctgatgatc gtcaaaccgg aaatgacaaa ctaactggtt cgtctccgcc
    56161 agtttgacca tctgcggcag ggtcaacgcg cccagtgtgt ttgccatctc ttcgttgata
    56221 ccgaggcgga acatcgcaga tgctttatcc tggacgatca aacgctgtgc aaggagtaaa
    56281 tatgacaaat tgatgtcata aatgtgtttt agcaactcgg atgtatgcat tgttcccatc
    56341 cagaataacc aactttattt ttgtgcgacg tagccgcacc ccgtgatgtc gccgggaagg
    56401 cccggtaaaa gaagcaaaaa ggtcaaatgc atagcagcgc tcagacatta tggacattgt
    56461 gacgtataac gcagcttccc actgggattc gccttacacg tttacatcaa tttttacaaa
    56521 tgcctaagat ttttcctaat tcgacgcaac tctactcgtc agtttcgtga catacaacgg
    56581 agcgggacgg cgattttaga aaatatgcga tgcagatcac ataatttaac agaatactta
    56641 cgataaaacc atcagtatgg cttttacttt gt
//
LOCUS       DAJVKX010000009        56024 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000009 DAJVKX010000000
VERSION     DAJVKX010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 56024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56024
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.009"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            87..974
                     /gene="rhtA"
                     /locus_tag="OPY25_000534"
     CDS             87..974
                     /gene="rhtA"
                     /locus_tag="OPY25_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HCS0926237.1"
                     /translation="MPGSTRKLPVWLPILVLLIAMSSIQSGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGLSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFIWVVLAVLGLWFLLPLGQDMSHVDLTGAALALGAGACW
                     AVYILTGQRAGAEHGPATVAVGSLITAIIFVPIGAVQAGDALWHWSILPLGLAVAVLS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPVLAAISGMIFLGETLTGIQILALCAIIAAS
                     MGSTLTIRREPQIKQVDVK"
     gene            1277..1780
                     /gene="dps"
                     /locus_tag="OPY25_000535"
                     /gene_synonym="pexB"
     CDS             1277..1780
                     /gene="dps"
                     /locus_tag="OPY25_000535"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HCS0926238.1"
                     /translation="MSTAKLVKTKASNLLYTRNDVSESDKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALTDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDLDKFLW
                     FIESNIE"
     gene            2257..3003
                     /gene="glnH"
                     /locus_tag="OPY25_000536"
     CDS             2257..3003
                     /gene="glnH"
                     /locus_tag="OPY25_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HCS0926239.1"
                     /translation="MKSLLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWDAIAKELKLDYTLKPMDFSGIIPALQTKNIDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDIKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGESLEAQQYGVAFPKGSDEL
                     REKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            3149..3808
                     /gene="glnP"
                     /locus_tag="OPY25_000537"
     CDS             3149..3808
                     /gene="glnP"
                     /locus_tag="OPY25_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HCS0926240.1"
                     /translation="MQFDWSAIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLAAGFAR
                     TFGGWFANHIALVFIEIIRGTPIVVQVMFIYFALPMAFNDLRIDPFSAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRRETIRHVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            3805..4527
                     /gene="glnQ"
                     /locus_tag="OPY25_000538"
     CDS             3805..4527
                     /gene="glnQ"
                     /locus_tag="OPY25_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HCS0926241.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIRQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGVKKEEAEKQAKALLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     SPQALIENPPSPRLQEFLQHVS"
     gene            4646..6868
                     /gene="ybiO"
                     /locus_tag="OPY25_000539"
     CDS             4646..6868
                     /gene="ybiO"
                     /locus_tag="OPY25_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HCS0926242.1"
                     /translation="MRWTLFILFCLLGAPAHAVAIPGVTTGTSTSQQAAPEPSPEQKK
                     AAYAALADVLENEASRNELIAQLREASTTPPTEPAPALAPPAAKDEKTVLENVTTVTR
                     QYGDAFATRFAQLYRNITDAPYKPFNSQTFTNALTHFLFLAVAVFGFYSVIRLCALPL
                     YRKMGLWARKKNRERSNWLQLPAMIAGAFIIDLLLLALTLFIGQMLSDNFHAGSRTIA
                     FQQSLFLNAFALIEFFKAILRLIFCPNVPELRPFAIQDATARYWNRRMSSLSSLIGYG
                     LIVAVPIISNQVNVQVGAMANVAIMLCITIWALYLIFKNKAEITQHLLSLAERSLAFF
                     SLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFISGMF
                     TRWIAKTITLSPHTQRNYPELQKRLNGWLSSALKVARFLTVCVAVMLLLNAWGLFDFW
                     HWLHYGAGEKMVDILIRIALILFFSAVGWTILASLIENRLASDIHSRPLPSARTRTLL
                     TLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFI
                     QFENGMNTGDLVTIGPLMGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGS
                     VVANYDVDRHEDADKANQALKDAVTALMETEDIRGLIIGEPTFAGIVGLTNTAFTLRV
                     SFTTLPLKQWTVRFALDSQVKKHFDLANVRAPVQTYQVLPAPAGGPPPDSLPPREPTI
                     "
     gene            complement(6865..7786)
                     /gene="rlmF"
                     /locus_tag="OPY25_000540"
                     /pseudo
     CDS             complement(6865..7786)
                     /gene="rlmF"
                     /locus_tag="OPY25_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
     gene            7991..8257
                     /locus_tag="OPY25_000541"
     CDS             7991..8257
                     /locus_tag="OPY25_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DksA/TraR family C4-type zinc finger protein"
                     /protein_id="HCS0926243.1"
                     /translation="MASGWANDDAVNEQINNTIEDAVARARGELPHGESRDECESCGD
                     PIPEARRKAVPGVRLCISCQQEKDLHNATFSGYNRRGSKDSQLR"
     gene            8542..8802
                     /locus_tag="OPY25_000542"
     CDS             8542..8802
                     /locus_tag="OPY25_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0926244.1"
                     /translation="MKTIKYAVAAIALSTLSFGAFAAEPVSASQTQNLHKIGVVSADG
                     ATTLDGLEAKLAEKAAAAGASAYNITSAVGNDKMSGTAVIYK"
     gene            complement(8958..9932)
                     /gene="ybiB"
                     /locus_tag="OPY25_000543"
                     /pseudo
     CDS             complement(8958..9932)
                     /gene="ybiB"
                     /locus_tag="OPY25_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459800.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
     gene            complement(9962..12106)
                     /gene="dinG"
                     /locus_tag="OPY25_000544"
                     /pseudo
     CDS             complement(9962..12106)
                     /gene="dinG"
                     /locus_tag="OPY25_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459799.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
     gene            complement(12314..13681)
                     /gene="rhlE"
                     /locus_tag="OPY25_000545"
     CDS             complement(12314..13681)
                     /gene="rhlE"
                     /locus_tag="OPY25_000545"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HCS0926245.1"
                     /translation="MSFDSLGLNPDILRAIAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITHQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQIEILVLDEADR
                     MLDMGFIHDIRRVLAKLPAKRQNLLFSATFSDDIKALAEKLLRNPLEIEVARRNTASE
                     QVTQHVHFVDKKRKRELLSQMIGQGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRITTPGYEPDPSIKAEPIQNGRQ
                     QRGGGGGGRGRGQNQGGAGRSQQPRRQDSGAAKAKPKPRTGEGKPAGDKARPPRRPRR
                     ITPAQ"
     gene            13911..14585
                     /gene="cecR"
                     /locus_tag="OPY25_000546"
     CDS             13911..14585
                     /gene="cecR"
                     /locus_tag="OPY25_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CecR"
                     /protein_id="HCS0926246.1"
                     /translation="MNIPTTTTKGEQAKSQLIAAALAQFGEYGLHATTRDIAALAGQN
                     IAAITYYFGSKEDLYLACAQWIADFLGEKFRPHAEKAERLFSQPAPDRDAIRELILLA
                     CKNMIMLLTQEDTVNLSKFISREQLSPTSAYQLVHEQVIDPLHTYLTRLVAAYTGCDA
                     NDTRMILHTHALLGEVLAFRLGKETILLRTGWPQFDEEKAELIYQTVTCHIDLILHGL
                     TQRSLD"
     gene            14585..15580
                     /gene="hlyD"
                     /locus_tag="OPY25_000547"
     CDS             14585..15580
                     /gene="hlyD"
                     /locus_tag="OPY25_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HCS0926247.1"
                     /translation="MKKPVVIGLVIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTV
                     NISFRVGGRLASLNVDEGDTIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRA
                     VEPGSMLNAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNDEARHE"
     gene            15573..17309
                     /locus_tag="OPY25_000548"
     CDS             15573..17309
                     /locus_tag="OPY25_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0926248.1"
                     /translation="MSEAVITLNGLTKRFAGMDKPAVAPLDCTIHSGYVTGLVGPDGA
                     GKTTLMRMLAGQLKADGGSASVLGFDPIQNDSELHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEIREKTFARLLEFTALGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGDGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPKALTQTMAGRSFLMSSPQENNRKLLQRALRLPQVSDGMIQGRSVRLILKKEATAA
                     DIRQAEGMPEITLNETAPRFEDAFIDLLGGAGTSESPLGSILHTVEGTAGETVIEAQE
                     LTKKFGDFAATDHVNFVVQRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGKALVLDMD
                     LKVSSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKIQRMSEAFGL
                     KSIASHPTDALPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQAADEQQADPTMEQAFIT
                     LINDWDKEHTHE"
     gene            17302..18432
                     /locus_tag="OPY25_000549"
     CDS             17302..18432
                     /locus_tag="OPY25_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0926249.1"
                     /translation="MSKSLSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGY
                     GINLDSSKLRVGILLEQQSQEALDFTHAMTGSPYIDATISDNRHELIEKMQAGRIRGL
                     VVIPVDFAQQMARDGDSAPIQVITDGSEPNTANFVQGYVEGIWQIWQQQRAEDRGDTF
                     EPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLST
                     EVTRVELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLVILFIITSLFLLSTLG
                     MGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFVS
                     TLQSLFLAGNIPVVLGVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            18548..19654
                     /locus_tag="OPY25_000550"
     CDS             18548..19654
                     /locus_tag="OPY25_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0926250.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYNEDNGKHSVELTQRFARAKAFTHVLLLNSPQEIQPTIDTQKALLLVRFP
                     ADFSRNLDTFQPAPMQLILDGRNSNSAQIAANYLQQIVKEYQQTLMDGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FVGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISA
                     LCATQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLGIVWGSLWPLLVIAATTGSAAYAMFRRKVM"
     gene            complement(19616..20026)
                     /locus_tag="OPY25_000551"
     CDS             complement(19616..20026)
                     /locus_tag="OPY25_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HCS0926251.1"
                     /translation="MKWQQRVRVATGLGCWQIMLHLLVVAMLVIGWMSGTLVRVGLGL
                     CVLYGVTVLLMLALQRHHEQRWRDVADVLEELTTTWYFGTALIVLWLLSRVLQNNVLL
                     ALAGLAILAGPAVVSLLAKDKKLHHFASKHRIRR"
     gene            20159..20917
                     /locus_tag="OPY25_000552"
     CDS             20159..20917
                     /locus_tag="OPY25_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCS0926252.1"
                     /translation="MTQHTRNFSFKVLTINTHKGFTAFNKRFILPELRDAVRTVGADI
                     VCLQEVMGAHEVHPLHIENWPDTTHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRGVSVGGSEKRGVLYCRITPPMLNRPIHVMCVHLGLRESHRQAQLTMLAGW
                     VNALPESEPVLVAGDFNDWRQKAGPPLNAAGLEEIFTRAHGRPARTFPVSMPLLRLDR
                     IYVKNANASSPGALPLRNWRHLSDHAPLSAEIHL"
     gene            20914..22155
                     /gene="clsB"
                     /locus_tag="OPY25_000553"
     CDS             20914..22155
                     /gene="clsB"
                     /locus_tag="OPY25_000553"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HCS0926253.1"
                     /translation="MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFE
                     DEVGKKLHAALLKAAQRGVKAEVLLDGYGSPDLSDAFVGELTSAGVIFRYYDPRPRLL
                     GLRTNIFRRMHRKIVVIDDRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADIL
                     QFEVENLPGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQ
                     AKREVIIANAYFFPGYRLLHAMRKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVK
                     GGVQVYEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANLIIHDRTFNQTLRD
                     NLQGIIVNDCKQVDESMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPHLAQVPP
                     PAQPEMETQDRVDPENSGVKP"
     gene            22155..23117
                     /locus_tag="OPY25_000554"
     CDS             22155..23117
                     /locus_tag="OPY25_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HCS0926254.1"
                     /translation="MAKSHPRWRLAKKVLTWLFFIAVVVLLVVYAKKVDWGDVWTVIR
                     DYNRTALLSAVGLVIVSYLLYGCYDLLGRLYCGHKLAKRQVMLVSFVCYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLGGIIFTFGVVQLPDHWYID
                     EGTLRILGIVLLLIIAVYLWFCAFAKRRHMTIKGQKLVLPSWKFALAQMAISSANWMA
                     MGAIIWLLMGQDVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFLALLAGEHTSQGT
                     IIAALLAYRVLYYFIPLLLALVCYLILESRAKKLRAKNERAMAK"
     gene            complement(23120..23362)
                     /locus_tag="OPY25_000555"
     CDS             complement(23120..23362)
                     /locus_tag="OPY25_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926255.1"
                     /translation="MSGVIIYRYVLLLAIISVTLATFCTLSSVFMGEFNEVLLLLFSW
                     SLLLFSRLQMNTSFFSAYVYFYRIKRVVLESENASA"
     gene            complement(23552..24259)
                     /locus_tag="OPY25_000556"
     CDS             complement(23552..24259)
                     /locus_tag="OPY25_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCS0926256.1"
                     /translation="MGPLAAIRIRQIAFIPATMLSLTYWYTALGLWCTAGIIWLTLYS
                     HFLITHVQPVVVLWISALLLGLGYGAVTCLSRFGTVVATLIYIAIITLTGVSLAYLFS
                     GGATIFVIVGIMFSLNALFIFYLNISSGLFRPLIFMAVSGIIAAIVVNSLVASSTLVW
                     IVSVLTVLVWTLITALEKSTLHGYARMLYHSEFSSLPRCALFGALTLYLGIINAVVTL
                     CRYIILMILEILLSFRP"
     gene            complement(24406..25111)
                     /locus_tag="OPY25_000557"
                     /pseudo
     CDS             complement(24406..25111)
                     /locus_tag="OPY25_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459785.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
     gene            complement(25159..25611)
                     /gene="moaE"
                     /locus_tag="OPY25_000558"
     CDS             complement(25159..25611)
                     /gene="moaE"
                     /locus_tag="OPY25_000558"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HCS0926257.1"
                     /translation="MHETRIVVGPAPFSVGEEYSWLAARDEDGAVVTFTGKVRNHNLG
                     DSVKALTLEHYPGMTEKALAEIVAKARSRWPLGRVTVIHRVGELWPGDEIVFVGVTSA
                     HRSSAFDAGQFIMDYLKTRAPFWKREATPEGDRWVEARDSDQQLAKRW"
     gene            complement(25613..25858)
                     /gene="moaD"
                     /locus_tag="OPY25_000559"
     CDS             complement(25613..25858)
                     /gene="moaD"
                     /locus_tag="OPY25_000559"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HCS0926258.1"
                     /translation="MIKVLFFAHVRELTGTDALDLPADFSTVESLRQHLATKSDRWAL
                     TLEDGKLLAAVNQTLVSFDHPLTAGDEVAFFPPVTGG"
     gene            complement(25851..26336)
                     /gene="moaC"
                     /locus_tag="OPY25_000560"
     CDS             complement(25851..26336)
                     /gene="moaC"
                     /locus_tag="OPY25_000560"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HCS0926259.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     VDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEHNRVRIESL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIGPVRLLAKSGGKSGDFKVDAH
                     D"
     gene            complement(26339..26851)
                     /gene="moaB"
                     /locus_tag="OPY25_000561"
     CDS             complement(26339..26851)
                     /gene="moaB"
                     /locus_tag="OPY25_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HCS0926260.1"
                     /translation="MSQVSAEFIPTRIAILTVSSRRGEEDDTSGHYLRDSAQEAGHEV
                     VAKAIVKENRYAIRAQVSAWIASDEVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTATLQSRAVAGVANNTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            complement(26873..27862)
                     /gene="moaA"
                     /locus_tag="OPY25_000562"
     CDS             complement(26873..27862)
                     /gene="moaA"
                     /locus_tag="OPY25_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HCS0926261.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPGGVTNN
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVGENDAIRQIAVTTNG
                     YRLARDAANWREAGLTGVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVK
                     VNTVLMRDVNHHQLDTFLAWIQPRPIQLRFIELMETGEGSDLFRKHHISGQVLRDELI
                     KRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLF
                     GDGGVSLRDLLQDDAQQYALEERISDALREKKQTHFLHQSNTGITQNLSYIGG"
     regulatory      complement(27850..27994)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            28259..29167
                     /gene="yvcK"
                     /locus_tag="OPY25_000563"
     CDS             28259..29167
                     /gene="yvcK"
                     /locus_tag="OPY25_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HCS0926262.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDAQLIPMSELPVDLMAIDDQGHEIYGEVNIDQLATP
                     PQEIMLTPNVPATREAVQAINDADLILIGPGSFYTSLMPCLLLDELAQALRRTPAPMV
                     YIGNLGRELSLPAASLTLVDKLAMMEQYIGKKVIDTVVVGPRVDVSAVNDRLVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     gene            complement(29262..31526)
                     /gene="slrP"
                     /locus_tag="OPY25_000564"
                     /pseudo
     CDS             complement(29262..31526)
                     /gene="slrP"
                     /locus_tag="OPY25_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459778.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector E3
                     ubiquitin transferase SlrP"
     gene            complement(31534..31707)
                     /locus_tag="OPY25_000565"
     CDS             complement(31534..31707)
                     /locus_tag="OPY25_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926263.1"
                     /translation="MATDYIILLKKEVMEARAFISQALQILNDLSEIMTTMASCLKLR
                     ISLSVTLGYVQIR"
     gene            complement(32016..34037)
                     /gene="uvrB"
                     /locus_tag="OPY25_000566"
     CDS             complement(32016..34037)
                     /gene="uvrB"
                     /locus_tag="OPY25_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HCS0926264.1"
                     /translation="MSKPFKLNSAFKPSGDQPDAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQVESTVPRYTIYPKTHYVTPRERILQAMEEIKDELADRRKVLLA
                     NNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGDEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGKGKGRSTAKAGIVE
                     LDMTPKALQQKIHELEEQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(34688..35374)
                     /gene="bioD"
                     /locus_tag="OPY25_000567"
     CDS             complement(34688..35374)
                     /gene="bioD"
                     /locus_tag="OPY25_000567"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HCS0926265.1"
                     /translation="MTKRYFVTGTDTEVGKTVASCALLQAATQLGYQTVGYKPVASGS
                     EMTTDGLRNSDALALQRNSSLPQPYSAINPYTFAEPTSPHIASADEGRAIDAAVLSRG
                     LRTLEAQADWVLTEGAGGWFTPLSATLTFADWVQTEQLPVILVVGVKLGCINHAMLTA
                     LAVEQAGLPLVGWIANDMQPPGARHGEYLATLRRVIPAPLLGEIPWLGVSPSQAATGQ
                     YLDLSPLERA"
     gene            complement(35367..36122)
                     /gene="bioC"
                     /locus_tag="OPY25_000568"
     CDS             complement(35367..36122)
                     /gene="bioC"
                     /locus_tag="OPY25_000568"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HCS0926266.1"
                     /translation="MAQVNKQAIAAAFGRAASQYEQHASLQQHSADALLTLLTGRQFA
                     SVLDAGCGPGRMSRYWRERGSEVTALDLSLPMLQQARDRQAAHHYLLADIEAIPHDAE
                     VFDLAWSNLAVQWCGDLRDALSELYRVVRPGGVVAFTTLCQGSLPELRQAWQAVDNRA
                     HANSFLPEEAIDHALRGWRASRHTQAMTLWFEDALSAMRSLKGIGATHLHEGRETDVL
                     TRARLRQIQLAWPQRQGKYLLTYHLFMGVIERD"
     gene            complement(36106..37263)
                     /gene="bioF"
                     /locus_tag="OPY25_000569"
     CDS             complement(36106..37263)
                     /gene="bioF"
                     /locus_tag="OPY25_000569"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HCS0926267.1"
                     /translation="MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNF
                     SSNDYLGLSQHPQIIRAWQQAATRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRA
                     LLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSR
                     LLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRG
                     TCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQAL
                     SASLAVIRSDEGRERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRL
                     AEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE"
     gene            complement(37260..38300)
                     /gene="bioB"
                     /locus_tag="OPY25_000570"
     CDS             complement(37260..38300)
                     /gene="bioB"
                     /locus_tag="OPY25_000570"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HCS0926268.1"
                     /translation="MARHPRWTLSQVTELFEKPLLELLFEAQQIHRQHFDPQQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAW
                     KNPHERDMPYLEKIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVTDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMT
                     PDTDDYYNAAAL"
     gene            38387..39676
                     /gene="bioA"
                     /locus_tag="OPY25_000571"
     CDS             38387..39676
                     /gene="bioA"
                     /locus_tag="OPY25_000571"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HCS0926269.1"
                     /translation="MTTDDLAFDKRHIWHPYTSMTSPLPVYPVERAEGCELVLASGER
                     LIEGMSSWWAAIHGYNHPQLNAAMKAQIDAMSHVMFGGITHQPAVNLCRKLVAITPEP
                     LECVFLADSGSVSVEVAMKMALQYWQARGESRQRFLTFRHGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDESDIAPFARLMAAHRHEIAAVILEPIVQGAG
                     GMRIYHPQWLRRIRNMCDREGILLIADEIATGFGRTGKLFACEHAGIAPDILCLGKAL
                     TGGTMTLSATLTTRQVAETISNGEAGCFMHGPTFMGNPLACAVACASLTLLESGEWRQ
                     QVASIESQLRAELAPAQSSPWVADVRVLGAIGVVETTHPVNMAALQRFFVGQGVWIRP
                     FGKLIYLMPPYIIRPDQLRRLTQAVNDAVHNETFFSH"
     gene            39734..40210
                     /locus_tag="OPY25_000572"
     CDS             39734..40210
                     /locus_tag="OPY25_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HCS0926270.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPMGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLTQGFGSGLVAVPDGVIQTRTDFGKAG
                     YGGAAPPKGETHRYIFTVHALDVERLDVDEDASGAMVGFNVHFHSLASASITAMFS"
     gene            complement(40295..41815)
                     /gene="hutH"
                     /locus_tag="OPY25_000573"
     CDS             complement(40295..41815)
                     /gene="hutH"
                     /locus_tag="OPY25_000573"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HCS0926271.1"
                     /translation="MNTMTLTPGQLSLSQLYDVWRHPVQLRLDASAIDGINASVACVN
                     DIVAEGRTAYGINTGFGLLAQTRIADEDLQNLQRSLVLSHAAGVGDPLDDAMVRLIMV
                     LKINSLARGFSGIRLSVIEALIALVNAGVYPLIPAKGSVGASGDLAPLAHLSLTLLGE
                     GKARWQGEWLPAQAALKKAGLEPVALAAKEGLALLNGTQASTAFALRGLFEAQELFAS
                     AVVCGALTTEAVLGSCRPFDARIHAARGQQGQIDVARLFRHLLTDTSAIAESHHHCHK
                     VQDPYSLRCQPQVMGACLTQLRQTKEVLLAEANAVSDNPLVFAEAGEVISGGNFHAEP
                     VAMAADNLALAIAEIGALSERRITLMMDKHMSQLPPFLVKNGGVNSGFMIAQVTAAAL
                     ASENKALAHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMAANTRGVIAVEWLAACQGI
                     DLREGLTSSPLLEQARQTLRERVAHYTQDRFFAPDIECATTLLAQGALQRLVPDFM"
     gene            complement(41817..43502)
                     /gene="hutU"
                     /locus_tag="OPY25_000574"
     CDS             complement(41817..43502)
                     /gene="hutU"
                     /locus_tag="OPY25_000574"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HCS0926272.1"
                     /translation="MPESKYRQQTIRAPRGTVLTAKSWLTEAPLRMLMNNLDPDVAEN
                     PHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLI
                     ANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHY
                     NGTLAGRWALTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATL
                     DDALARITRYTREGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPS
                     GWCWEEYQKNAQSDPRGTMQAAKRSMAAHVRAMLAFSKMGVPTFDYGNNIRQMAKEMG
                     VENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHW
                     LDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVA
                     SPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCD
                     GTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLNLPMVAATQGKG"
     gene            complement(43698..44423)
                     /locus_tag="OPY25_000575"
     CDS             complement(43698..44423)
                     /locus_tag="OPY25_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine utilization repressor"
                     /protein_id="HCS0926273.1"
                     /translation="MYSSRSRSAPAPFYETVKQDICKKIAGGVWQPHDRIPSEAELVA
                     QYGFSRMTINRALRELTDEGWLVRLQGVGTFVAEPKGQSALFEVRSIAEEIAARHHQH
                     RCEVLTLERVRANAIQASALNVNESDVIFHSIMVHYENDLPVQIEDRCVNADIAVDYL
                     TQDYRQTTPHAYLSRIAPLTEGEHIVEAVRATAQECAWLTIKEHEPCLLIRRTTWSAS
                     RIVSHARLLFPGSRYRLQGRFIS"
     gene            complement(44468..45409)
                     /locus_tag="OPY25_000576"
     CDS             complement(44468..45409)
                     /locus_tag="OPY25_000576"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HCS0926274.1"
                     /translation="MTQWYPASPALWQGRDDSIEAPDARRLFQTVTRSEAFFPENWQQ
                     KIALMGFACDEGVKRNSGRPGAAGGPDALRKALANMASHQGHERLVDLGNWVAPTPDL
                     EGAQQALRDAVSRCLRAGMRTLVMGGGHETAFGHGAGVLDAFAQESVGIINLDAHLDL
                     RQTDRATSGTPFRQLAQLCDAQSRAFHYACFGVSRAANTQALWREAQWRNVTVVEDLD
                     CHDALAQMTQFIDKVDKIYLTIDLDVLPVWEMPAVSAPAALGVPLIQVLRLIEPVCRS
                     GKLQAADLVEFNPRFDEDGAAARVAARLGWQIAHWWR"
     gene            complement(45406..46629)
                     /locus_tag="OPY25_000577"
     CDS             complement(45406..46629)
                     /locus_tag="OPY25_000577"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HCS0926275.1"
                     /translation="MRQLLPGDTVWRNIRLATMDPQRQAPYGLVDSQALIVREGHICD
                     IVPETQLPVSGDNIHDMQGRLVTPGLIDCHTHLVFAGNRAAEWEQRLNGASYQHISAQ
                     GGGINATVSATRACAEETLYLLARERMMRLASEGVTLLEIKSGYGLELATEEKLLRVA
                     AKLAAENAIDISPTLLAAHATPAEYRDDPDGYITLVCETMIPQLWQKGLFDAVDLFCE
                     SVGFNVAQSERVLQTAKALGIPVKGHVEQLSLLGGAQLVSRYQGLSADHIEYLDEAGV
                     AAMRDGGTVGVLLPGAFYFLRETQRPPVELLRRYQVPVAVASDFNPGTSPFCSLHLAM
                     NMACVQFGLTPEEAWSGVTRHAARALGRQATHGQIRAGYRADFVVWDAEQPVEIVYEP
                     GRNPLYQRVYRGQIS"
     gene            46867..48150
                     /locus_tag="OPY25_000578"
     CDS             46867..48150
                     /locus_tag="OPY25_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HCS0926276.1"
                     /translation="MNTLSVSRLALALAFGVTLSACSSTPPDQIPSDQTAPGTASRPI
                     LSANEAKNFVAARYFASLTPNTAPWSPSPITLPAQPDFVVGPAGTPGVTHTSIQAAID
                     AAMVKRTNKRQYIAIMPGDYQGTVYVPAAPGSLTLYGTGEKPIDVKIGMAIDGEMSVA
                     DWRRAVNPGGKYMPGKPAWYMFDNCQSKHAATIGVMCSAAFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDKVQINKVNILGRQNTFFVTNSGVQNRLQTDRQPRTLVT
                     NSYIEGDVDMVSGRGAVVFDNTNFQVVNSRTQQEAYVFAPATLSNIYYGFLAINSRFN
                     ASGDGVAQLGRSLDVDANTNGQVVIRDSVINEGFNVAKPWADAVISKRPFAGNTGTVD
                     DKDEVQRNLNDTNYNRMWEYNNRGVGSKVVTEPKQ"
     gene            complement(48294..49289)
                     /gene="pgl"
                     /locus_tag="OPY25_000579"
     CDS             complement(48294..49289)
                     /gene="pgl"
                     /locus_tag="OPY25_000579"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HCS0926277.1"
                     /translation="MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHHGRFVFVGSYN
                     AGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTLSDDG
                     HLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTL
                     DMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEAQ
                     PRGFNIDNSRKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY"
     gene            49453..50271
                     /locus_tag="OPY25_000580"
     CDS             49453..50271
                     /locus_tag="OPY25_000580"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphatase"
                     /protein_id="HCS0926278.1"
                     /translation="MTARVIALDLDGTLLTPHKTLLPSSLEALSRAKEAGFQLIIVTG
                     RHHVAIHPFYQALALETPAICCNGTYLYDYQAKTVLDADPMPVDKALQLIDLLDEHQI
                     HGLMYVDDAMLYEHPTGHVVRTSRWAQTLPPEQRPTFTQVSSLAQAARDVNAVWKFAL
                     TDEDIPRLQRFGQHVEQALGLECEWSWHDQVDIARKGNSKGKRLTQWIEAQGGSMKNV
                     IAFGDNYNDISMLEAAGTGVAMGNADEAVKARADFVIGDNTTDSIAKFIYTHLL"
     gene            complement(50272..51330)
                     /gene="modC"
                     /locus_tag="OPY25_000581"
     CDS             complement(50272..51330)
                     /gene="modC"
                     /locus_tag="OPY25_000581"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HCS0926279.1"
                     /translation="MLELNFSQTLGTHCLTLNETLPASGITAIFGVSGAGKTSLINAI
                     SGLTRPRKGRIVLNGRVLHDAENGICLTPEKRRIGYVFQDARLFPHYKVRGNLRYGMA
                     KSMTGQFDKLVSLLGIEALLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLAREINIPMLYVSHSLDEILHLADKVMVLEDGQVKAFGPLEEVWG
                     SSVMHPWLPKEQQSSILKVSVLEHHPHYAMTALALGDQHLWVNKLNQPLQSTLRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVANCYDDNGQVEVQLEIGGRTLWARISPWARDELN
                     IKPGLWLYAQVKSVSITA"
     gene            complement(51333..52022)
                     /gene="modB"
                     /locus_tag="OPY25_000582"
     CDS             complement(51333..52022)
                     /gene="modB"
                     /locus_tag="OPY25_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HCS0926280.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCRFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGQWLYDWFGLTFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFLTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESAAARLCVISIVLALISLLISEW
                     LARISRERTGR"
     gene            complement(52022..52795)
                     /gene="modA"
                     /locus_tag="OPY25_000583"
     CDS             complement(52022..52795)
                     /gene="modA"
                     /locus_tag="OPY25_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCS0926281.1"
                     /translation="MAHSWLRLVAGATLSFVIAGHALADEGKITVFAAASLTNAMQDI
                     AAEYKKEKNVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAADKKAVDTTTRE
                     TLLGNSLVVVAPKASEQKPFTIDNKTDWIHLLNGGRLAVGDPQHVPAGIYAKEALQKL
                     GAWQTLEPKLAPGEDVRGALALVERNEAPLGIVYGSDAVASKGVNVVATFPEDSHKKV
                     EYPIAIVEGHKNAAVSAFYDYLKGPQASAIFKRYGFTTK"
     gene            complement(52962..53111)
                     /locus_tag="OPY25_000584"
     CDS             complement(52962..53111)
                     /locus_tag="OPY25_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AcrZ family multidrug efflux pump-associated
                     protein"
                     /protein_id="HCS0926282.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGIGQKDQ
                     SRQNR"
     gene            53240..54028
                     /gene="modE"
                     /locus_tag="OPY25_000585"
     CDS             53240..54028
                     /gene="modE"
                     /locus_tag="OPY25_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HCS0926283.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINDMNQLSEHMLVERATGGKGGGGAVLTRYGQRLIQLYDLLGQIQQKAFDV
                     LSDDDALPLDSLLAAISRFSLQTSARNQWFGTITARDRDQVQQHVDVLLADGKTRLKV
                     ALTAQSGERLGLEEGKEVLILLKAPWVGITRDAAVARAADNQLSGTISHIERGAEQCE
                     VLMALPDGQTLCATIPTADAATLKEGDDVIAWFNADRVIIATLC"
     gene            54096..55571
                     /gene="modF"
                     /locus_tag="OPY25_000586"
     CDS             54096..55571
                     /gene="modF"
                     /locus_tag="OPY25_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HCS0926284.1"
                     /translation="MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSA
                     LARALAGELPLLTGERQCQFTRITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTT
                     AEIIQDDVHHPARYAMLAQQFGISALLNRRFKYLSTGETRKALLCQALMSEPELLILD
                     EPFDGLDVTARQQLAQRLTALNQAGMTLALVLNRFDEIPDFVQFAGVLADCTLAETGT
                     TAELLQRALVAQLAHSERLTDVQLPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPIL
                     HHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQ
                     GETQLLFVSHHAEDAPACITHRLEFVPEGERYKYVSGRCNN"
     gene            55742..>56024
                     /locus_tag="OPY25_000587"
     CDS             55742..>56024
                     /locus_tag="OPY25_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2167 domain-containing protein"
                     /protein_id="HCS0926285.1"
                     /translation="MAFRFPQIILFLLAAMLFCPSSYAEQKPTAAQEARKTAVEVAVE
                     GMSRAAVAGPTKISLGDKATLNLPEGFTWIPAKEAAVFMREIGNYVDDEY"
BASE COUNT        12786 a        15704 c        14532 g        13002 t
ORIGIN      
        1 tttttcaacg aatcctcaac cgctccgggg aatttccatt acactgccac ctttactcgt
       61 actgacattt tttgacagga gaaaggatgc cggggtcaac acgtaaacta ccagtctggt
      121 tgcccatttt ggttttgctc attgccatgt cctctattca gagtggcgct tcactggcaa
      181 aatcgttatt tcctcttgtt ggcgcgccgg gtgtaacggc gcttcgtctg gcgttgggaa
      241 cgcttatcct tatcgccttt ttcaaaccct ggcgtttgcg ttttgccaaa gagcagcggc
      301 tgcctttact gttttatggt ctgtcgctgg gcgggatgaa ctatctattc tatctgtcga
      361 ttcagacggt gccgttgggt attgcggtcg cgctggaatt taccggccct ctggcggtcg
      421 cgctgttttc atcccggcgt ccggtagatt ttatttgggt cgtactggct gtgcttggac
      481 tctggttcct gctgccatta ggacaagata tgtctcacgt cgatcttacc ggggccgcgt
      541 tagcgctcgg cgctggcgcc tgttgggctg tctatattct taccggccag cgagcaggcg
      601 cggaacatgg tccggccacg gtggcggtag gctcgctgat taccgccatc attttcgtgc
      661 cgattggcgc agttcaggct ggcgatgcgc tatggcactg gtcgattctt cccttagggt
      721 tagcggtcgc tgtgctttct acggcgctgc cttattcact ggaaatgatt gcgctgacgc
      781 gcctgccaac tcgcaccttc ggtacgctga tgagcatgga acccgtgctg gccgccattt
      841 ccgggatgat ttttctgggc gaaacgctta cgggcataca aatcctggcc ctgtgcgcca
      901 tcattgccgc ctcaatgggt tctaccctaa cgattcgccg cgaaccgcaa attaaacaag
      961 ttgacgtaaa atagtttctt attctgcatg atgtgcataa tcatgcagaa tatcacctcg
     1021 ttattcacct tttattatcg cgctattact tcgtcatttt ttgtcatatt ttttctcatt
     1081 ttttacatta aaatgagaat tattacccat caaacaacaa actcatctaa ccaattgatt
     1141 cataaccaaa ataaatatta aatcttgtct gtactattaa agtgataggt aaattcaaaa
     1201 aagcgaagtt aaaaaccggt gctatactta ttttcgttaa ttacctggga cacaaacatc
     1261 aagaggatat gagattatga gtaccgctaa actggtaaaa acaaaagcgt ctaatctgct
     1321 ttatacccgt aacgatgtat cagagagcga taaaaaagcg acggttgagt tgcttaatcg
     1381 tcaggtgatc cagttcattg acctgtcgct gatcacgaaa caggcccact ggaacatgcg
     1441 cggtgctaac tttattgccg ttcatgagat gctggatggc ttccgtaccg cactgaccga
     1501 tcatctggat actatggccg agcgcgccgt acagcttggc ggtgtggcgt taggcaccac
     1561 gcaagttatc aacagcaaaa ctccactgaa aagctatccg ctcgacatcc ataacgtgca
     1621 ggatcactta aaagaactgg ccgatcgcta cgctgttgtc gctaatgatg ttcgcaaagc
     1681 tatcggtgaa gccaaagatg aagacactgc cgatatcttt accgccgcat cacgcgacct
     1741 cgataaattc ctgtggttta tcgaatccaa catcgaataa atctatctct accctgaata
     1801 cttcgagttg caggaaggta caaacgcagc gaatccgcag gagcctgact tccgtcggtc
     1861 actgaagcga acgcacctgc aacttgatgt acacaggtat ataagtcatc cctatacccc
     1921 tgcctggcac aggggttttg cacttaaata gtgcacatgt cttgtacttc ccttcgataa
     1981 aagtgaatta tttgtaataa ttacatcaca caatcgttaa ttaaagattg ttttaacaac
     2041 aatttttacg ctaaatagac cctgtatctc tactttgtta ttcatgcact aaatcagtgc
     2101 cccaaaacag tgcagcatac tggttttgcc cgacttattg tgcacaggaa tgattgacgc
     2161 ttctgttaaa acaatgagtt acataattgg catgattttt tcattacgct acatgttctc
     2221 gcaggggatc gccccgtgga tagaaaagga aatgctatga agtctctatt aaaagtttca
     2281 ctggctgcac ttaccctggc ttttgcggtg tcttcgcacg ctgcggataa gaaactcgtt
     2341 gtggcaaccg atacggcgtt cgttccgttt gaatttaaac agggcgacaa atacgtcggt
     2401 tttgatgttg atctgtggga cgctatcgcg aaagaactga agctggacta caccctgaaa
     2461 ccgatggatt tcagcggcat tattccggca ttacaaacca aaaatatcga tctggcgctg
     2521 gcgggtatta cgattacgga cgagcgtaaa aaagcgatcg acttttccga tggctattac
     2581 aaaagcggtc tgctcgtgat ggtgaaagcc aacaataacg atattaaaag cgttaaagac
     2641 ctcgatggca aagtcgttgc cgtgaagagc ggaaccgggt cggtggatta cgcgaaagcg
     2701 aatatcaaaa ccaaagacct gcgtcagttc ccgaacattg ataacgcgta catggaatta
     2761 ggcaccaacc gcgcagacgc cgttctgcac gatacgccga acatcctgta ctttatcaaa
     2821 accgcaggca acggccagtt caaggcggta ggcgaatcgc tggaagcaca gcaatacgga
     2881 gttgccttcc cgaaaggcag cgatgaactg cgcgagaaag tcaacggcgc gctgaaaacg
     2941 ctgcgtgaga atggcaccta taacgaaatc tacaaaaaat ggttcggtac agaacctaaa
     3001 taaaacgacc tgatgttggc ttgtggcccg gtagtgagga cgctcaccgg gcctacagct
     3061 cttttccgtg acggataaga cactttcacg ccatttccgc gccggataga gcatttgact
     3121 atttacacca cggtaacagg aacgacatat gcagtttgac tggagcgcca tctggcccgc
     3181 cattccgctt ttgcttgagg gcgctaaaat gaccctgtgg atctcggtcc tcggtctggc
     3241 tggcggcctg gttattggac tggcggcagg ttttgcccgt acgtttggcg gctggttcgc
     3301 taaccacatc gccctggttt tcattgaaat tattcgcggc acgcctatcg ttgtccaggt
     3361 catgtttatc tactttgccc tgccgatggc atttaatgat ttgcgtattg atccgttcag
     3421 cgcagcggtc gtgacaatta tgattaactc cggcgcttat atcgcggaaa ttactcgtgg
     3481 cgcagtacta tccattcaca aaggttttcg cgaagcaggt ctggcgctgg gcctttctcg
     3541 ccgggaaacc atccgccatg ttattttacc gcttgctctg cgccgtatgc tgccgccgct
     3601 gggcaaccag tggatcatta gcatcaaaga cacctcgttg tttattgtta tcggcgtagc
     3661 cgagctgacc cgtcagggcc aggaaattat tgccggtaac tttcgcgccc tggaaatctg
     3721 gagcgccgtg gccgtcttct atttgatcat tacgctggtg ctgagcttta ttttgcgtcg
     3781 tcttgaaaga aggatgaaaa tcctgtgatt gaatttaaaa acgtctccaa gcactttggc
     3841 cccacccagg tgctgcataa cattgattta aacatccgtc agggcgaagt ggttgtgatt
     3901 atcggccctt ccggttcggg taaatccacg ttattacgct gtatcaataa actggaagag
     3961 atcacctccg gcgatctgat tgtcgatggt ctgaaagtca acgatccgaa agtagacgaa
     4021 cggctgattc gccaggaagc cggcatggtg tttcaacagt tttatctgtt cccgcatctg
     4081 accgcgctcg aaaacgtgat gttcggtcct ctgcgcgtgc gcggcgtaaa gaaagaagaa
     4141 gcggaaaaac aggcgaaagc tctgttagcg aaagttggac tggcggaacg ggcgcaccac
     4201 tacccctccg agctttccgg aggtcaacaa cagcgcgtcg ccattgcccg agcgctggcc
     4261 gtgaagccga aaatgatgct ctttgacgag ccaacctccg ctctggaccc tgaactgcgc
     4321 catgaagtgc tgaaagtcat gcaggatctg gcggaagaag gcatgaccat ggtcattgtc
     4381 actcacgaaa tcggctttgc cgaaaaagtc gcctcacggc tgattttcat cgataaaggc
     4441 cgtattgccg aagatggcag tccgcaggcg ttgatcgaaa acccgccaag cccacgttta
     4501 caggaatttt tacagcacgt ctcctgagat atcgcccttc ctgccctgcg gcaggaaggg
     4561 catcatggaa tagtcccatt tcattttccc tcccctgcgc catctatact tagtgttttg
     4621 cgtctctttt ctcactggag gagtcatgcg gtggaccctg ttcatccttt tttgtctact
     4681 gggcgcgcct gcccatgcgg tcgccatacc cggcgtgacc acggggacat caaccagcca
     4741 gcaagcagcg ccagagccca gtcctgaaca aaaaaaagcg gcctatgcgg ccctggctga
     4801 cgtactggag aacgaggctt cacgtaacga attgatagcg caactccgcg aagcctcaac
     4861 cacgccgccg accgagccag cgccagcgct tgccccgcct gcggccaaag atgagaaaac
     4921 ggtactggag aacgtcacca ccgttacccg tcagtacggc gatgctttcg ctacccgttt
     4981 cgcccagctt tatcgcaaca tcaccgatgc gccgtacaag ccgtttaact cgcaaacctt
     5041 caccaacgcg ttaacccact ttttatttct ggccgtcgcg gtatttggtt tttatagcgt
     5101 gatacggctt tgcgccctgc cgttatatcg aaaaatgggc ctgtgggcgc gcaagaaaaa
     5161 ccgtgaacgc agcaactggt tacagctccc ggcgatgatc gccggcgcgt ttattatcga
     5221 cctgctgcta ctggcgctca ccttatttat cggtcagatg ctcagtgata atttccatgc
     5281 cggaagtcga actatcgctt ttcagcaaag cctgttcctg aatgccttcg cgctgataga
     5341 gttctttaaa gcgattctgc ggcttatttt ttgccctaat gtaccggaat tacgcccatt
     5401 cgcgattcag gatgcgacag cgcgttactg gaatcgccgt atgagttccc ttagcagttt
     5461 gattggctac gggctgattg ttgccgttcc gattatttcc aaccaggtga atgttcaggt
     5521 cggggcgatg gcgaacgtgg cgatcatgct ctgcatcacc atctgggcgc tgtacctgat
     5581 ctttaaaaac aaagcggaga ttacgcaaca tttattaagt ctggcggaac gatcattagc
     5641 cttttttagc ctgtttatcc gcgcctttgc gctggtgtgg cactggctgg ccagcgctta
     5701 ctttatcgtg ctgtttttct tctcgttatt cgacccaggc aatagcctga agtttatgat
     5761 gggcgcgacc gtgcgcagtc tggcgattat tggcatcgcc gcgtttatct ccggtatgtt
     5821 tacccgctgg atagcgaaaa ccatcaccct gtcgccccat acgcagcgca attacccgga
     5881 attacaaaag cggcttaacg gctggctctc ctcggcgcta aaagtcgcac gctttttgac
     5941 cgtctgcgtc gccgttatgc tgttgctcaa cgcctggggg ctattcgatt tctggcactg
     6001 gctacattat ggcgcggggg aaaagatggt cgatatcctc atccgtatcg cgttaatctt
     6061 attcttctcc gccgtgggat ggacgattct cgccagtctg attgagaatc gcctggcctc
     6121 cgatattcat agtcgcccgc tacccagcgc ccgcacgcgc acgctgctga cgctgttccg
     6181 caatgcgctg gcagtgatta tcagtaccat aaccatcatg atcgtgttat cggaaatcgg
     6241 cgtcaatatc gcgccgttgc tggctggcgc gggggcgtta ggtctggcta tctctttcgg
     6301 ttcgcaaacc ctggtgaaag atattattac cggcgttttt attcagtttg aaaacgggat
     6361 gaataccggc gacttagtca ccataggccc gctgatgggg acggtcgaaa gaatgtcgat
     6421 tcgttccgtc ggcgtgcggc aggataccgg ggcataccat attatcccgt ggtcctcgat
     6481 caccactttc gccaactttg tgcgcggtat cggctctgtt gtcgccaact atgacgtgga
     6541 tcgccatgag gatgcggata aagcgaatca ggcgctgaaa gacgcggtaa cggcgctgat
     6601 ggagacggag gatattcgcg ggctgattat cggcgaaccc acgttcgccg gtattgtcgg
     6661 tttaacgaac acggcgttta ctttacgcgt gtcgttcacc acgctaccgc tcaagcagtg
     6721 gacggtgcgt tttgcccttg atagccaggt gaaaaagcat tttgatctgg ccaatgttcg
     6781 cgcgccggtg caaacgtatc aggttctgcc cgcccccgcc ggcggcccgc cgcctgattc
     6841 actgccgccg cgcgaaccga cgatttagcg tttacgggtg ataaaacggc gacgctggtc
     6901 gtcatccata aaggtccagg cgataaagcg gctttgcttt tgcccctggg ccatctcttt
     6961 tttcaccact ttcaccgcgc cagcctccgt caacgcccgg taaagcggtg gtaaattctc
     7021 gccgcgcgac accaacgtcg taaaccacaa cacctgacgg cggaaggttt ggctttcagc
     7081 aatcattttt ttaataaagg cgacttcgcc gccttcgcac catagctcct gctgttgacc
     7141 gccaaagttc agcgcatcat ctttattctg ccccaaattg cggcgcttac gctcgctgcc
     7201 cgcgcgggct gcggcggcgg agtcgtgaaa aggcgggtta caaagcgttg cgtcataaaa
     7261 ttcattttta tgaataatac cggtaaaaat ggccgccgga tctttttgcc gacgcagacg
     7321 aatggcgcgg cttaaccccg tattagcctg aatgatagcc tgcgcgctgg acatcgctgc
     7381 gtcgctgact tcactaccgg taaatcgcca gccatattca tggacgccga taagcggata
     7441 aatacaattg gcgcccacgt ccagaatagt tgcctgcgcc ggaatactcc ctgttgtttc
     7501 gccaagcaga tccgccagat gatggatata atccgcacga ccaggcactg gcggacataa
     7561 aaaccctggc ggaatgtccc agtgtgtaac ggcataaaaa tgcgccaaca acgccttatt
     7621 gagcgctttt accgcttgcg gattagcaaa atcaacgctc tgttcaccgg cgggcgtgcg
     7681 gataagataa ggacgtcaat tccggcgtgg tctgacacag tgcggcgaga tcataacggt
     7741 gttgatggcg gttgcgcggg tgtaaccccg gtttctgggc ggacatggca ttctcctttt
     7801 agcagcggcg taagataccc gtataacgcc acggggtaaa tataccaccg cgaattccct
     7861 gcctcgctcg ttttatcggc tctctgaatg acattggctc tgctcatggt ctgaaaagat
     7921 cgcgcgatgc gattttttca cctgacggcg ctacacttaa cctcaggtac cctaaaatca
     7981 ggagagcgtg atggcatccg gctgggcaaa tgacgacgca gtgaatgaac aaatcaacaa
     8041 taccattgaa gatgccgttg cccgcgctcg cggcgaactt ccccacggcg aaagtcgcga
     8101 tgaatgcgaa tcttgcggcg atcctatccc tgaagcgcgg cgtaaagccg taccgggcgt
     8161 tcggttatgc atatcctgcc aacaggagaa agatttacat aacgcaacat tttcaggata
     8221 taatcgtaga ggttcaaaag acagtcagtt acgctgactt ttctttaccg aaaccgccag
     8281 tatcatccat tcctttacgc tcatgctttt tagcgttctg cgtcgcagaa tgtgccgtta
     8341 acctcgactc tgtaaagcca gatgacaaga acggtaaatt ccaccgttga attaattaat
     8401 aatcaatagg ttatttgtca ttcaaaaatt ttgagcaagg ccgtcaattc tattcgattt
     8461 tatctttcgc aaaaaaccgt gatactcatc acatcgacgg aacatcgtcc cataaacaga
     8521 ataacctgcg agagattaat catgaaaacc attaaatatg ctgttgcagc catcgcgctt
     8581 tccacccttt cttttggcgc ttttgccgca gaaccggtta gcgcgtctca gacgcaaaac
     8641 ctgcataaaa tcggcgtagt gtctgccgat ggcgccacca cgctggatgg cctggaagct
     8701 aaactggctg aaaaagccgc cgctgctggc gcaagcgctt ataacatcac ctccgccgta
     8761 ggtaatgaca aaatgagcgg cactgcggtg atttataaat aatttacctg cccgccagat
     8821 ttcaggctgt aacatcgctg ttgtttgaat tctgacgggt attaccctcg tctgtttgcc
     8881 aacagaccca ctgctccaac cctcattaac cctgtttgtt acccttattt gcccgtccgc
     8941 cactggacgg gcttttttta ttcgctaaaa gcctgttcga cgcgcgcaag cccgtcttct
     9001 aacgtcgccg cctctcccgt cgcaaccaga caacaggcca tttgcgtttt taatgattgc
     9061 ggcaccggct cgtggccggc aaggcagcgc tcaatccagc gcgcggtgat ttcaggatct
     9121 ttagtcgcag gcagtgaaag cggctcgtcg tacgtgtcgc tctggcgctc atgcagtacc
     9181 tgcacgccgc ggctatcaat caggctgatt tgcggacagc gttgcgggtt ggcatagact
     9241 tcgccttcgg taccatgcat cagcaaagcc cacccgccaa tgcggctaaa aaaggtcgcc
     9301 acacgcagaa catattcagg atgagaaacg cttgataaac gcagcgcggc atcctcagca
     9361 aatggcgtcg ccagcttggc cagtgaatgc gcgctgttac gcacgcccat ccgccagcgc
     9421 atcgctagct gtttttccag cggcgggcag agcgcgctca ccgggataaa caccggctgg
     9481 cgcccgtcca gtttggcctg cgcttgtccg ccgtgtaggg tgggttcaat ccccatcagc
     9541 tcaaatatag tttccgtcag tacgcgggtc ggatcttcac tgacgccgtg tactacgact
     9601 ggaaagccca atttatgcag caagatagcc agcagcggcg ttaaattcgc ctgtttacgc
     9661 gcgccgttat agctgggaat aacgaccggc aacggcctat ctgcgggcgg tgtcagtttg
     9721 atggcatgat tctacatggc ttcataaaag cccagcattt cggcttcgcc ttcgccttta
     9781 atacgcagcg ccatcaatat actgcccatt tccaggtcgg ggacgtcgcc attcagcatt
     9841 cgggtataca aaccgcgcgc ggtatccaga tccagatcgc gggcgtgatt tttacctcgc
     9901 ccgatctctt tgatgatctt gcgataatcc attgaaagct ccttgaagtg tgctcacagc
     9961 attaacaccg tcggcggcgt gcaggttttg cttttggttt tactataacg tctggcacgg
    10021 caggctgctc tatcggaaaa acaggtaagg cattcagtaa acgctgtccg tagtttttgg
    10081 tcaacaaccg cttatcataa atgaccactt ctccccgaca ggcgtggcta cggatcaatc
    10141 gccctacctg ctgaattaaa ttaaaagacg cgcttggtaa gctttgtacc tcaaacggat
    10201 aacgattcag actttttagc cattcgcctt cggtgatcac gaccgggctg tcgatcggcg
    10261 ggaaggcaat tttatggata tggacctgcg tcagtagctc gcctttaaga tccagccctt
    10321 cggcaaaaga ctgaagccca accagcacgc tgcgttcgcc gctctccacc cgtttacggt
    10381 gcagctccac cagccggtaa cgcggctggt cgccctggac caggaggagt aagcgcacat
    10441 cagcgacatg ctccagaaaa cgctgcatcg cccgcccgct ggcgaacagt accagcatac
    10501 catgatgttt tttgctctcc agttgctcgc gaaaataggc tgccatttcg gcaatatgct
    10561 gctcttcgtt atcaatagtg ggttcgtagc gcatttgagg aatcaccagt ttcccctgtt
    10621 ccacatgatt aaacggcgaa tccagcgcca caaagcggtc gccggctttt tcttttaagc
    10681 cgctcatttc ctgcaggcgc gaaaagctat tgagcgagcg cagtgtcgcc gaggtgacaa
    10741 taatgtgcgg tacgctgcgc cataacaatc tttccagctg ctcgctgacg cggataccga
    10801 cacaatggaa ccagacgtgg agttgccctt cgcgtatttc acgcgtcgcc catttggaca
    10861 ccggcgcgcc tgaagactgc gccatcgaag ccagtcacca taatttactt tgcgcctcga
    10921 acattcccag cgcccggttc atctgtaaaa tcacccgatg caaacgcaca atatcgtgcg
    10981 acccggtttt ttcgctgaga tcgttgagaa aggactccgc cagcccacgc aacgtctcgg
    11041 tcagcttcgc cagtcgctgg cagatttcca tgacctcatc aggcaactcg cccattgcaa
    11101 aacggtgctc cgcctcctgc gctgcgggca tatacagatt aagaatggca ttgagcgagg
    11161 cgatcagttc gtacacctcc tcgcaatggg cgttaagtcg ctcaggattc gctaacggcg
    11221 gcgtggtctt agggcgaaat tgctccatgc aggtcgccac cagtttgctg aacaggtcca
    11281 gttgcaagcg ataccaggag gcggtaattt ccgcgctcat ctccagcgca tcgcgagcga
    11341 catcgggcag atgatgacct tcatccagta ccaacagcag atgctttggt tccggcagta
    11401 cggcttcact ttccatcgcc gccattacta gcgcgtgatt cgccaccacg acttccgctt
    11461 cctgtatttc acgtcgggcg acaaagaatg gacattcgcg gtaatagtga cagttgcggt
    11521 tcagacaact ggctttatcg gtacttaatc gccgccacag atcgtcgtca atagcaatgt
    11581 cggtatgatc ccgcagacca tcccatttgt aaccgtcaag atcccctttc agcctggcgc
    11641 agcgcttttg ctcttcctgg ttgttaggcg tcagttcgtc atcaagaaag gcgagcagat
    11701 cctgctgcgt aggctcgcta ctggcgagcg ccgccaggtt tcgcggacac acgtaacgcc
    11761 cgcggccaaa ggcggcggta aagcgcagat cggggatgat ttttcgtagc agcggcaaat
    11821 ctttgctaaa gatctgatcc tgtaacgcca cgttagcggt actgaccacc agtgtttttt
    11881 gctcttcccg ggcaatggcg ataccgggaa taagatagga gagggttttc ccgacgccgg
    11941 tcggcgcttc aatagccaga tgtctccctt cttccccggc cagcgttctg gcgacgtcag
    12001 caatcatctg ccgctgcggc gcacggggaa taaagtcggg aatctgatcc tgaagcgcct
    12061 tataccaggc ggcgatttgc gctttcagcg cagcggtcaa tgccatgaga aaacctgaag
    12121 tactgtataa acagccacta ttgtgtcaca tttcaggggc gggaagtacc ttttttgccg
    12181 gttctggaag gcggctcgca acgcgatgtg tattttgccg gatggcggtg caagcacctt
    12241 acccggccta cgtatttgca tagtccgtag gcccggtaag cgtcgcgcta ccgggcatgt
    12301 tgccggataa aatttactgg gcaggcgtga ttctgcgcgg gcgacgcggc ggacgtgctt
    12361 tgtcgccagc gggtttcccc tcgcctgtgc gcggttttgg tttcgccttc gccgccccgc
    12421 tatcctgacg tcgcggctgc tgactgcgcc ccgctccccc ctgattttgt ccgcgtccac
    12481 gaccgccgcc accgccgccg cgctgctgac ggccgttctg aatcggctcc gctttaatcg
    12541 acgggtccgg ctcatagccc ggcgtcgtaa tgcgtgggat ctcttttttc agcaattttt
    12601 cgatatcacg caacagttta tgctcgtcaa cacagaccag cgacagcgcc tcgccagttg
    12661 ccgccgcgcg accggtacgg ccaatacggt gtacataatc ttccggcacg ttcggcagtt
    12721 catagttgac cacgtgcggc agctcttcaa tatccagacc acgcgccgca atatccgtcg
    12781 ccaccagcac gcgaatatcg ccggatttaa aatcggccag cgcgcgggta cgtgcgccct
    12841 gcgatttatt accgtggatc gccgcgctgc gaataccgtc tttattaagc tgttccgcca
    12901 gatggttcgc gccatgcttg gtgcgggtga agaccaacac ctgctgccag ttgccctggc
    12961 caatcatctg cgacaacagt tcacgtttgc gttttttatc gacaaagtgc acgtgctgcg
    13021 tcacctgctc tgaggccgtg ttgcggcgcg ccacttcgat ttccagcggg ttgcgcaaca
    13081 gcttttcggc gagcgctttg atgtcgtcgg agaacgtggc ggagaacagc agattctgac
    13141 gcttcgccgg cagtttcgcc agcacgcgac gaatgtcgtg aatgaagccc atatccagca
    13201 tacggtcggc ttcatccagt accagaatct caatctgatc cagcttcacg gcattttgat
    13261 gttccaggtc gagcagacgt cccggcgtcg ccaccagcac atccacgccg ccgcgcagtt
    13321 tcatcatctg cggattaatg cttacgccgc caaataccac cagcgagcga atattgagat
    13381 atttactgta atctctgacg ttttcaccaa tttgcgccgc cagctcgcgg gttggcgtga
    13441 ggatcaacgc acgtaccggg cgacgacctt tagcgtgcgg ctgatgggta atcagatgct
    13501 gcaacaatgg cagggtaaaa cccgccgttt taccggttcc ggtctgggcg ctagccatca
    13561 gatcgcggcc ttccagcacg gcgggaatcg cctgttgctg aataggggta ggttcacggt
    13621 aaccctgctc ggcaatggcg cgcaggatat cagggtttaa tcccagggaa tcaaaagaca
    13681 taactactcc ggaccgcccc gaccgttacc ggtgtagttt tcagggagat gctcaaattt
    13741 ggaatgacaa aaaccacaat gtcatgaagg ggcggagtgt agcagttttt gtgatgcggc
    13801 gcataaatta tcccgaaagg tggcaaagac aaattaatcg accacactgg acaagtgcca
    13861 ttatgagtca taatcttaat caatcgattg attaataatt agggcgtgtg atgaatattc
    13921 ccaccacgac caccaagggc gagcaggcga aaagtcagct cattgccgcc gcactggcgc
    13981 agtttggcga gtatggcctc catgccacca cgcgcgatat cgccgcgctg gcggggcaaa
    14041 atattgccgc tattacttac tatttcggct caaaagagga tttatacctc gcctgcgccc
    14101 agtggattgc tgattttctt ggcgaaaaat ttcgccccca tgctgaaaaa gcggaacgtc
    14161 tgtttagcca gcctgcccct gaccgagacg ccatacgcga gctcattctg ctcgcctgca
    14221 agaacatgat tatgctgctg acgcaggaag acaccgttaa cctgagcaaa tttatttcac
    14281 gcgagcagct ctctcccaca tcggcctatc aattggtcca tgaacaggtt atcgatccgt
    14341 tgcacaccta tctgacaaga ttggttgccg cttataccgg ctgcgacgcc aatgatacgc
    14401 gcatgatttt gcatacccat gccttactgg gcgaagtact agcgtttcgt ctcggcaaag
    14461 aaactattct gttacgtacc ggctggccgc agtttgatga agaaaaagcg gagctgattt
    14521 accagacggt aacctgccac atcgatctta ttctgcacgg tttaacgcaa aggagtctgg
    14581 actgatgaaa aaacctgtcg ttatcggact ggtaatcgca gcgatcgtcg ctgtgattgc
    14641 cggtggaacc tggtggtatc aaagtcggca ggacgatggg ctgacgctat acggtaatgt
    14701 cgatatccgt accgtcaata tcagctttcg cgtcggcggc aggctggcgt cgctgaatgt
    14761 tgatgaaggc gatactatca aagccggaca ggtgctcggc gaactggatc acgcgccata
    14821 cgaaaacgcg ctgatgcagg cgaaagctgg cgtgtcggtc gcgcaggcgc aatatgattt
    14881 gatgctggca ggctatcgcg atgaagagat agcccaggcc gccgccgccg tcagacaggc
    14941 gcaagccgcc tatgactacg cgcaaaactt ttataaccgt cagcaaggat tgtggaaaag
    15001 ccgcaccatt tccgctaacg atctggaaaa tgcccgctca tcgcgcgatc aggcgcaggc
    15061 gacgctgaag tccgcgcagg ataaactgag ccagtaccgt accggtaatc gtgaacagga
    15121 tatcgcccag gcgaaagcca gtctggaaca ggcaaaggcc caactggcgc aggcgcagct
    15181 tgatttgcag gacaccacgc ttatcgcgcc tgccaacgga accttgctca cccgcgcggt
    15241 cgagcctggc agtatgctga acgccggcag cacggtatta acactctcgc tgacccgccc
    15301 cgtctgggtg cgcgcctatg tcgatgaacg caacctcagt cagacgcaac cggggcgcga
    15361 tattctgctg tataccgatg gacgtcctga caaaccttac cacggcaaga ttggtttcgt
    15421 ttcccccacc gcggaattta cgccgaaaac cgtcgaaacg ccggatctgc gtaccgatct
    15481 cgtctatcgc ctgcgcatta tcgtcaccga tgcggacgat gcgttacgcc aggggatgcc
    15541 agtcacggtg aaatttaatg acgaggcacg gcatgagtga ggccgttatt acgctgaacg
    15601 gtctgacgaa gcgctttgcg ggaatggata aacccgccgt cgcgccgctc gactgtacca
    15661 ttcattccgg ttatgtcacc gggctggtag ggccggacgg cgcaggaaaa accacgctga
    15721 tgcgtatgct ggcgggccag ctcaaagccg atggcggcag cgcgtccgta ttgggcttcg
    15781 acccgataca aaacgacagc gagctgcacg cggttctggg ctatatgccg cagaaattcg
    15841 ggctgtatga agatcttacc gtcatggaga accttaatct ctatgccgat ttgcgcagcg
    15901 ttaccggcga gatacgggaa aagacctttg cccgtttgtt ggagtttacc gccctcggcc
    15961 ctttcactgg ccgtctggcg ggaaaattgt ccggcgggat gaagcaaaaa ctggggctgg
    16021 cctgtacgct ggtcggcgaa ccgaaagtgc tgctgttgga tgaaccgggc gttggcgttg
    16081 acccgatttc acggcgcgag ttgtggcaaa tggtccacga actggcgggc gacgggatgc
    16141 tgattttatg gagcacctcc tatctggatg aagccgaaca gtgtcgcgat gtgctgctga
    16201 tgaatgaagg cgagctgctc tatcagggcg aacctaaagc gctgacgcaa acgatggccg
    16261 gtcgtagctt tctgatgagt agtccacagg aaaacaaccg taagttacta cagagagcgc
    16321 tcagactgcc gcaggtgagc gacggcatga ttcaggggcg ttcggtacgc ctgatcctga
    16381 aaaaagaggc gaccgcagca gatattcgtc aggccgaagg gatgccggaa atcaccctca
    16441 atgagaccgc gccgcgtttc gaagatgcgt ttatcgatct gcttggcgga gcgggaacct
    16501 cggagtctcc gctgggttca atcctgcata cggttgaagg cactgccggc gaaacggtga
    16561 ttgaagcgca ggaactgacg aaaaaatttg gcgatttcgc ggccacggac catgttaatt
    16621 tcgtcgtaca acgcggcgag atttttggcc tgctcggccc gaacggcgcg ggtaaatcaa
    16681 ccacctttaa aatgatgtgc ggcctgctgg tgccgacgtc cggcaaggcg ctggtgctgg
    16741 atatggacct gaaagtcagc tccggcaaag cccgtcagca tctgggctat atggcgcaaa
    16801 aattttcgct ttacggcaac ctgacggttg agcagaacct gcgttttttc tccggcgtct
    16861 acggtttgcg gggccgcgcg caaaatgaaa aaattcagcg catgagtgaa gcatttggtc
    16921 tgaaaagcat cgcgtcgcat cccaccgatg cgctgccgct gggttttaaa cagcgactgg
    16981 cgctggcctg ctcgctgatg cacgaaccgg atattttatt ccttgatgaa ccaacgtccg
    17041 gggttgatcc cctcacccgc cgtgaatttt ggctgcacat taatagcatg gtggaaaaag
    17101 gggtcacggt aatggtgacg acccacttta tggatgaggc ggaatattgc gatcgcatcg
    17161 gactggttta tcgtgggaag cttatcgcca gcggtacgcc ggacgatctc aaagcgcagg
    17221 ccgccgatga gcaacaggcc gatccgacga tggagcaggc ctttatcact ctcatcaatg
    17281 actgggataa ggagcatacg catgagtaag tctctctcct ggcgccgcgt gcgtgcgttg
    17341 tgcgtcaaag agacgcgcca gatcgtgcgc gatcccagta gctggctgat tgcggtggtg
    17401 atcccgctgc tgttgctgtt tatttttggt tacggcatta acctcgactc cagcaagctg
    17461 cgggtgggga ttctgcttga acagcaaagc caggaggcgc tggatttcac tcatgcgatg
    17521 accggttcac cctatatcga cgcgaccatt agcgataatc gtcatgaatt aattgaaaaa
    17581 atgcaggccg gacgcattcg cggactggtg gtgattccgg tggatttcgc gcagcaaatg
    17641 gcgcgcgacg gtgacagcgc gccgattcag gtgattaccg acggcagcga gccaaatacc
    17701 gccaacttcg ttcagggcta tgttgaaggc atctggcaaa tctggcaaca gcagcgcgcg
    17761 gaagatcgcg gcgacacctt tgaaccgctt atcgacgtcc agacgcgcta ctggtttaac
    17821 ccggcggcga tcagtcagca ttttatcatt cccggggcgg tgaccattat catgacggta
    17881 attggcgcca tcctcacctc gctggtcgtt gcccgcgaat gggaacgcgg cacgatggag
    17941 gcgctgctct caaccgaagt gacgcgtgtt gaactgctgc tgtgtaagct tattccctat
    18001 tattttctcg gtatgctggc gatgctgctc tgtatgctgg tatcggtgtt tattctcggc
    18061 gtgccgtatc gcggttcgct ggtaattctg tttatcatca ccagtctgtt tttactgagt
    18121 acgctgggga tggggctgtt gatttccacc atcactcgca accagtttaa cgccgcgcag
    18181 gtggcgctga acgccgcgtt tttgccttcg attatgctgt ccggatttat cttccagata
    18241 gacagtatgc ctgcggtgat ccgcgcggtg acctatatta ttccggcgcg ctattttgtc
    18301 agcaccctgc aaagtctgtt tctggccggc aatattccgg tcgtgttagg cgttaacgta
    18361 ctgtttttaa tcgcctcggc ggtgatgttt attggcctga cgtggctaaa aaccaaacga
    18421 cggctggatt aaatatgtgt atggataatt gtcgtcgtag gccggataag gcgctcacgc
    18481 cgccatccgg cattatgcct gatgcgcttt gcttatcagg cctacaaact ggactgagag
    18541 gacgggcatg tttcatcgtt tatggacgtt aattcgcaaa gaactgcaat cgcttttacg
    18601 cgaaccgcaa acgcgcgcga tcctgattct gccggtgctg attcaggtca tcctgtttcc
    18661 gttcgccgcg acgcttgaag tcactaacgc gactatcgcc atctataacg aagataacgg
    18721 caaacattcg gtagaactta cccagcgttt tgcccgcgcg aaagcgttta cccatgtgct
    18781 attgctgaac agtccgcagg agatccagcc gactatcgat acgcaaaaag cgctgctgct
    18841 ggtgcgcttc ccggcggatt tctcgcggaa tctggatacc ttccagcctg cgccgatgca
    18901 actcattctt gatggacgta actccaacag cgcgcaaatt gccgccaatt atctgcaaca
    18961 gatcgtcaag gagtatcagc agacattgat ggacggcaag ccaaagccca acaatagcga
    19021 actggtggta cgcaactggt ataacccgaa tctggactac aagtggtttg tggtgccctc
    19081 gctgatcgcc atgatcacca ctatcggcgt gatgatcgtc acttcgctgt ccgtcgcccg
    19141 cgagcgtgaa caaggcactc tggatcagct gctggtctct ccgctcacca cctggcagat
    19201 tttcgtcggc aaagcagtgc cggcgctgat tgtcgcgacc ttccaggcca cgatcgtgct
    19261 ggctatcggc atttgggcat accaaattcc cttcgccggt tcgttagcgc tgttttattt
    19321 cacgatggtg atttacgggc tgtcgctggt aggctttggc ttgctgatat cagcactttg
    19381 cgccacgcaa cagcaggcgt ttatcggcgt ctttgtcttt atgatgccgg cgattttgct
    19441 ctcgggttat gtctcgccgg tggaaaatat gccggtctgg ctgcaaaacc tgacgtggat
    19501 aaatcctatc cgccacttta ctgatattac taagcaaatt tatcttaagg acgcgagtct
    19561 ggggattgtc tggggaagtt tgtggccgct actggtgata gcggccacca cgggttcagc
    19621 ggcgtatgcg atgtttagac gcaaagtgat gtagcttttt atctttcgcc agtagcgaga
    19681 ccacggcggg cccggccagg atagccagcc ccgccagcgc cagtaaaaca ttgttttgca
    19741 atacgcggga tagcagccag aggacaatca gcgcggtgcc aaagtaccag gtggtagtca
    19801 gctcttccag cacatccgcc acatcgcgcc agcgctgctc atgatggcgc tgcaacgcca
    19861 gcatcaatag taccgtcacg ccataaagca cgcataatcc caggccgacg cgcactaatg
    19921 tgccgctcat ccagcctatt accagcatcg ccactaccag taaatgcaac ataatctgcc
    19981 aacaaccgag gccggttgcg acacgaacgc gttgttgcca cttcatggct tttctcctga
    20041 agcatttttc tctcattatt cagagtaccg aactttacgg aaaattccgt aagaccgcat
    20101 ctttttgtga cgacgactac actatttcaa tcaggatagt gacgcggaca ggaagaaaat
    20161 gactcaacac acgcgaaatt tttcattcaa agtgctcaca attaatacgc acaaaggttt
    20221 taccgccttt aataaacgct tcatcctgcc ggagctgcgc gacgccgtca gaacggtcgg
    20281 cgccgatatc gtctgtctgc aagaagtgat gggcgcgcat gaagtgcatc cgctgcatat
    20341 cgaaaactgg ccggacacta cccactatga atttttggcc gacaccatgt ggagcgattt
    20401 cgcctatggc cgtaatgcgg tctatccgga aggccatcac ggtaacgcgg ttctttctcg
    20461 ctatcccatt gaacattatg aaaatcgcgg cgtctcggtc ggcggtagcg aaaaacgcgg
    20521 cgtgctctat tgccgcatta cgccgcccat gctcaaccgc cctatccacg tcatgtgcgt
    20581 acatctcggc ctgcgggaga gccaccgcca ggcgcagtta accatgctgg cgggatgggt
    20641 gaatgccttg ccggaatcag aaccggtgct ggtggccgga gactttaatg actggcggca
    20701 aaaggccggc ccgccgttaa acgcggccgg gctggaggag atattcaccc gtgcccatgg
    20761 ccgaccggcg cgcacattcc cggtgagtat gccgctgctg cgactcgatc gtatttacgt
    20821 caagaatgcg aacgccagtt ctcctggggc gctaccgttg cggaactggc gacatttatc
    20881 agaccatgcc ccccttagcg cggagatcca tctatgaaat gcggctggcg tgaaggtaat
    20941 caaattcagc tactggaaaa cggcgaccag ttctatcctg ccgtgtttga ggctatcgct
    21001 caggcacagc aaaaaatcat tctggaaacc tttatcttgt ttgaagatga ggtgggtaaa
    21061 aaactccatg ccgctctgct aaaagctgca cagcgcggcg taaaagccga agtattactc
    21121 gacggctacg gctctcccga tctcagcgac gcgtttgtcg gcgaattaac ctcggcgggc
    21181 gtgatttttc gctattacga cccccgcccg cgtctactgg ggttgcgaac caatatcttc
    21241 cgccgaatgc accgcaaaat tgtggtgatt gatgatcgta ttgcctttgt cggcggcatt
    21301 aactactccg ccgaacatat gtcggattac ggcccgcagg cgaaacaaga ctacgcggta
    21361 cgggtcgaag ggcctgttgt ggccgatatc ctgcaattcg aagtcgagaa tctgccgggg
    21421 caaagccccg cgcgccgctg gtggaagcgc catcatcagg ctgaagaaaa tcgccacccc
    21481 ggcgaagcgc aggcgctgtt tgtctggcgg gataatgaag aacaccgcga cgatatcgaa
    21541 cgtcattatc tgaaaatgct gacccaggca aagcgtgaag tgattatcgc taacgcctat
    21601 tttttccccg gctatcgctt gctccacgca atgcgtaaag ccgcccgccg tggcgtgagc
    21661 gtaaaactga ttgtccaggg agaaccagac atgccgatag tcaaagtcgg cgcgcggttg
    21721 ctctataact atctggtgaa gggcggcgtg caggtttatg aataccgacg ccgtccgctg
    21781 catggcaaag tggcgctgat ggacgatcac tgggccacgg tagggtcgag taatctcgat
    21841 ccgctcagcc tgtcgcttaa ccttgaagct aacctgatca ttcacgatcg tacttttaac
    21901 cagaccctac gcgataactt acaaggcatc atcgtgaatg attgtaagca ggtcgatgag
    21961 tctatgctgc cgaaacgtac ctggtggaac ctgaccaaaa gcgtgctggc gttccacttt
    22021 ttacgccatt tcccggcgct ggtcggctgg ctacctgcgc ataccccgca tctggcgcag
    22081 gttcccccgc ctgctcagcc ggaaatggaa acccaggatc gcgttgatcc agaaaattca
    22141 ggagtgaagc cctaatggct aaatcgcatc cgcgctggcg gctggctaaa aaagtgctga
    22201 cctggctgtt ttttattgcg gtcgtcgttc tgctggtggt ttatgctaaa aaggtcgact
    22261 ggggtgatgt ctggaccgtc atccgcgact ataaccgcac ggcgctttta agcgctgtag
    22321 gactggtgat cgttagctat cttctgtacg gctgctacga cctgcttgga cggctttatt
    22381 gcggccataa gctggcgaag cgacaggtga tgttggtatc gtttgtctgc tatgcattca
    22441 acctgacgct cagcacctgg gtcggcggga tcgggatgcg ttaccgacta tactctcgcc
    22501 tcggattgcc cggcagtact attacgcgca ttttctcact cagcattacc actaactggc
    22561 tgggctatat tctgcttggc ggcatcattt ttaccttcgg cgttgtccag cttcccgacc
    22621 actggtatat cgatgaaggc acgctacgta ttctcggtat cgttttattg ttgattatcg
    22681 cggtctatct gtggttttgc gcctttgcga agcggcggca tatgacgatt aaagggcaga
    22741 aactggtgct gccgtcatgg aaattcgcgc tggcgcagat ggcgatctcc agcgcgaact
    22801 ggatggcgat gggcgccatc atctggctgc tgatgggtca ggatgtgaac tatttctttg
    22861 tactgggcgt actgctggtg agcagtatcg cgggcgtcat cgtgcatatt ccggcaggca
    22921 tcggcgtgct ggaggccgta ttcctcgcgt tgctggcggg cgaacatacg tcgcaaggca
    22981 cgattatcgc cgccctgctc gcgtaccgtg tgctttacta ttttattccc ctgttgctgg
    23041 cgctggtgtg ctatctgatc ctggagagcc gggcgaagaa gttgcgggcg aaaaacgagc
    23101 gggcgatggc gaaatgaatt taagcagacg cgttttcgct ttccagcaca acgcgtttta
    23161 tccggtaaaa ataaacatat gctgagaaaa aagacgtatt catctgtaag cgggaaaaaa
    23221 gcagcaatga ccagctaaac agcagcagga gcacttcgtt aaactcaccc atgaatactg
    23281 atgacagggt acagaacgtt gccaacgtaa cggaaataat ggccagcaat agcacatacc
    23341 ggtaaataat gaccccgctc atgttcccat gacaatccgg taatgaaatg agaaatcagc
    23401 gctggcgggc atttcttatt aaaatcctca ccgccatttt taatggcgcg agtgacgtct
    23461 ttagcttcac aaaacgctaa ccaaaattgt ttgccacata atttactcat tatacccatc
    23521 atcaccaacc tgaataaaaa acctgcaaca cctacggcct gaaagataat agtatttcca
    23581 gaatcatcaa aatgatataa cgacacagcg taaccacagc attaataatg ccaaggtaaa
    23641 gcgtcagcgc gccaaataaa gcgcaacgag gcagggatga aaactcgctg tggtataaca
    23701 tgcgggcata accatgaagt gtcgattttt ctagtgctgt aatcaatgtc cataccaata
    23761 ccgtcagcac actgactatc cagaccagag tgctactggc caccaggcta ttgacaacta
    23821 tcgcagcgat gatcccgctt accgccataa aaattaacgg cctgaataga ccagaactga
    23881 tattcaggta gaaaataaat aaggcattaa gactaaacat gattccaaca atcacgaaaa
    23941 tggtcgcgcc acctgagaaa aggtaagcta atgacacgcc ggtaagcgta atgatggcaa
    24001 tatatatcaa cgttgcgaca acagtgccaa agcgggaaag acaggtaacg gccccatacc
    24061 ccaggccaag caaaagtgct gatatccaca aaacaacaac aggttgaacg tgagttatca
    24121 aaaaatgact atacaacgtt aaccatataa taccggcggt acaccatagt cccagcgcag
    24181 tataccaata ggtaagggat aacattgtcg cgggaataaa tgctatttgc cgtatacgta
    24241 ttgcagccag aggtcccact tgtcatttat cactcttctt attatcaccg taataagaat
    24301 ggcaagcgca ggaaaatatt tctaagatgt ttatgctgtt ttgccctaaa tatagtccta
    24361 aaaaaaatcc tggcgcaggg ccaggatttt aagagatcaa tatgattagc ggcgattgcc
    24421 aaaaatacgc agtaacatca ggaacaagtt gataaagtcc aggtacagcg ttaacgcgcc
    24481 gagaatcgaa tacttacgca gattagcgct atcgcgggta tctatttgct cgccgatatt
    24541 tttcagtttc tgcgtgtcat aggcggtcag accgacaaac accaccaccc cgatataggt
    24601 taccgcccac atcagcgctt cactcttcag ccagaaattg accagcgagg ccagaacgat
    24661 accaataagc gccataaaca gcatattgcc gaaaccgcta agatcgcgtt tagtggtgta
    24721 cccatacagg ctcatggcgc caaacattcc ccccgtcacc acaaacgtgc tggcgatgga
    24781 ggaataggtg taaacgataa aaatactgga taacgtcaaa tccggttagc gccgaataga
    24841 gcataaacag cgtcgtcgcc attccggcgc taagtttatg caccagtccc gacagaacaa
    24901 acaccagcgc aagctgagca atgattaagc caaagaaggt gatcttactg gaaaagacaa
    24961 acatcatgac ggctggcgta ttagccgcat accacgcgat aaacgcggtc agtaacagtc
    25021 cgaccgtcat ccagccatac acttgcgcca tataggtctg caggccagac cgcgcctgca
    25081 ctattgaatc agatcgtgga aatctgtcca tgatgaactc ctgtgtggaa atgataccct
    25141 aaagcgtatc acattctgct accaacgttt cgccaactgc tggtcgctgt cgcgcgcttc
    25201 gacccagcga tcgccttccg gcgtggcttc acgcttccag aacggcgcac gggttttcag
    25261 ataatccata atgaactgac cggcgtcgaa cgcgctactg cggtgcgcgc tggtgacgcc
    25321 gacaaacaca atctcatcgc ccggccataa ttcgccaacg cgatgaatca ccgtgacccg
    25381 ccccagcggc cagcgggaac gcgccttcgc gacgatctcc gccagagctt tctcagtcat
    25441 gccgggataa tgctccagcg tcagcgcctt aacgctatcg cccaggttat gattgcgcac
    25501 ttttccggta aaggtgacga ccgcgccgtc ttcgtcgcgc gccgccagcc aggaatattc
    25561 ctccccgacg ctaaacggcg cagggccgac tacaattcgc gtttcgtgca tgttagcccc
    25621 ccgtgactgg cgggaaaaac gccacttcat cgcccgccgt cagcggatgg tcaaaactta
    25681 ccagcgtctg gttgaccgcc gccaacagct tgccgtcttc cagcgtcagc gcccaacgat
    25741 cgctctttgt cgccagatgc tgtcgcagcg actcaacggt ggaaaaatct gctggaagat
    25801 ccagcgcatc agttcctgta agctcgcgaa cgtgggcgaa gaaaagcact ttaatcatgc
    25861 gcatccacct taaaatcccc cgatttgccg ccgcttttcg ccagcagacg caccggacca
    25921 attactatat ctttttgtac cgctttgcac atgtcgtaga tggttaacgc cgcgacggac
    25981 gccgcggtta atgcttccat ttcgacgccg gttttaccgg tcagacggca cagagactca
    26041 atacgtacac ggttatgctc cggctcggcc tgaagctgaa tctccacttt acttagcagt
    26101 agcgggtggc acagcgggat cagctcccag gtgcgtttag cggcctgaat accggcaata
    26161 cgggcagtcg cgaaaacatc gcccttgtgg tgtttgccat caacaatcat cgccagcgtt
    26221 tcactacgca tggtaacgaa tgcttccgcc cgtgcttcac gaacggtttc cgctttcgcg
    26281 gaaacgtcca ccatgtgcgc ttcgcctgcg gcgtttatat gggttaattg cgacatcgtt
    26341 atttctttaa atgagggtga aaattacatg ggcgtgtacg ggcatccagc tgcggcgcaa
    26401 tgatattctc ccatgcggtt ctgcacgctt ttgtggagcc cggcatggcg aaaatcaagg
    26461 tgttattcgc cacgccagct accgcgcgcg actgcagagt tgcggtgccg atctcttcaa
    26521 acgagagcat gcgaaacact tcgccaaatc cttccacttc acgatcgaac agcggcaaca
    26581 gcgcttccgg cgcctgatcg ccttcggtca aaccggtccc gccagttatc aatacgacct
    26641 gcacctcatc actggcgatc caggcggaaa cctgggcgcg aatcgcgtaa cggttctctt
    26701 taacgatggc tttcgccacc acttcatgcc cggcctcctg cgccgaatca cgcagataat
    26761 gaccggaggt gtcgtcttct tcgccgcgtc ggctggaaac agtaagaata gcgatgcggg
    26821 tcgggataaa ttcagcgctg acctgactca tctgaaatct ccttattaag gattaaccgc
    26881 caatgtaaga taaattttgc gtaataccag tattgctctg gtgaaggaaa tgggtctgct
    26941 ttttctcccg caacgcgtcg gaaatacgtt cctcaagcgc gtattgctgc gcatcatcct
    27001 gtaacaggtc gcgtaaactc acgccgccgt cgccaaacag acataaatgc agcttaccga
    27061 cggacgaaac acgcaggcgg ttacaggtgg cgcagaaatc tttttcgtac ggcataatga
    27121 gaccgatctc accggcgtaa tcggggtgac aaaaaacctg cgccggacca tcgctacgct
    27181 ggcggagctg gtggatccaa ccgcgcttaa tcagctcgtc acgtaatacc tgacccgaaa
    27241 tatgatgttt gcggaagaga tcgctcccct cgcccgtctc cataagttca atgaagcgta
    27301 gctgaatggg gcgaggctga atccaggcaa ggaaggtatc caactgatgg tgattcacgt
    27361 cgcgcatcag cacggtgttg actttcacct tttcgaaacc ggcgtcaaag gcggcatcga
    27421 tgcccgccat cacctggcgg aatttgtcct gaccggtaat cgcatggaac tgacgcgcat
    27481 ccagactatc cacgctaaca ttgacgcccg tcagccccgc ttcgcgccag ttcgcggcat
    27541 cgcgcgccag tcgataaccg ttagtggtca ccgcgatctg gcgaatagca tcattttcac
    27601 ccacggcggc aatgatgtcg gtaaaatcgc ggcgtaatga aggctcgccg ccggtaagac
    27661 gcaccttttc cgtgccaaga ctggcaaaag cgcgcgtaac gcgacgaatt tcatcgacgg
    27721 taaggaaacc gttgttagtg acgccgccag gtttgtagcc atccggcaga cagtaggtgc
    27781 aacgaaagtt acacacatcg gtaatcgaca aacgcaagta gtaaaactta cgcgcgaaag
    27841 catcggtaag ttgtgaagcc atgtacacct ttccaaatac gggaggcgga gtcatttctt
    27901 cctgcgccct ggtggcaaac gttaaacgtt gtcacggcca aagcaccata tcaaaaatga
    27961 cccaggtgca gaggctagag tgtttattgt ggttacgccg atactagcgt gtaaatgaca
    28021 atttcgccat cacgctttcg ctatataaac atatacatag cgatatgatc gtgctattta
    28081 gcgacagaat acgtgaaaat cacactttta cattgatata tatcatttag ccgtggtaac
    28141 gccctcgcta taaaggggta gtcgggaata attaattgtc ttttagccgg tcggctaatt
    28201 gctgaaaacc cgcgacttgc gctactgtag cgctgcttat ttgacttcag gaatttttat
    28261 gcgcaatcgt acgctggctg accttgatcg tgtcgttgcc ctcggcggag ggcatggatt
    28321 aggacgcgtc ctctcctcgc tttcttcatt aggttcgcgc ctgaccggca ttgtgactac
    28381 cacagataac ggggggtcaa ctggccgtat tcgccgctcg gaaggcggga tcgcctgggg
    28441 cgatatgcgc aactgtctga atcagttaat taccgaaccc agcgtcgcat ccgctatgtt
    28501 tgagtaccgt tttggcggta atggcgaact ttctggtcat aacctcggaa atttgatgtt
    28561 aaaggcgtta gatcacctga gcgtgcggcc tctggaagcg attaatttaa ttcgtaatct
    28621 gcttaaagtg gacgcgcagc tgatcccgat gtcggagcta ccggtagatc tgatggcgat
    28681 tgacgatcag gggcatgaga tttatggcga ggtgaatatc gatcagttag cgacgccgcc
    28741 gcaggagatc atgttaacgc caaacgttcc ggcgacgcgg gaagcggtac aggccattaa
    28801 tgacgcggat ctgattctga ttggccctgg cagtttttat accagcctga tgccttgcct
    28861 gctgctggat gaactggcgc aggcgctgcg gcgcacccca gcgccaatgg tgtatatcgg
    28921 caatctgggt cgcgaactga gtctgcccgc cgccagttta acgctggtcg ataagctggc
    28981 gatgatggag caatatattg gcaaaaaagt cattgacaca gtagtggttg ggccgcgagt
    29041 tgacgtcagt gcggtgaacg atcggctggt gattcaggaa gtgctggagg ccagcgatat
    29101 cccctatcgc cacgatcgtc agttattaca caatgcgctg gaaaaagcgc tacaggcgtt
    29161 gggttaagcc cgtttaccga cgacgctgcg cttatcagaa gcctgtttac accgaagggt
    29221 aaacaggctc tctccctctt ctgataaact gcgttcagct atcaccagta ggcgctcatg
    29281 agcgagctca cctctttttt cagcaatata ttctccatga tctcagtaaa gagggtctga
    29341 ttgatctctt ccattatccg cattccagcc atgcgctctg cgtcaggatc acctgctatt
    29401 cctaacgctt ccagttcagc attgacccgg ctctgatact catccgtttc aatacactca
    29461 gcccttttgg ccatcatttc acgccactct tctggcgcta tacgctccag cactttatgc
    29521 cacggccccc acagcgcaaa ccatttgtga aaatccctat tttcagcaat ttttatcctt
    29581 atttccgcct cgtccaggtc agactcagtg atacccgaaa cgttataaaa tcgcatatcc
    29641 tgggtcattg ttgtcagcga cagcgactct cgtaactgat tctgaaaacc cagatatact
    29701 tcgatttcgt caataaaaaa cagccgtttt accttttctc tggcgagcga ttctatttgc
    29761 tccagccgaa agatttcacg ccccgccata atcagttccg ctaagtggct atcaaaggcg
    29821 cctctttcag catcatgaac caacgtcgct tcctgcattt gatggtatgc cagtgtgacc
    29881 cgatcttcac agcttatcgt tgcatccatc gctataataa atgcggtttc tcttagtgcg
    29941 ctatcatcag ccaggcgcat tagccaggcg gagacttgtt ccttaaaatc cgaatgtcgg
    30001 gtgttctgcg tatcgctaag acgatccaga aacatgctga aggctgccgc gtttacttcc
    30061 gtctcaaacg cccgccattg gttgacgtct tcctcctcga gattggttag ccacccctgg
    30121 acagcttgat gcagtggtcg agttacccga acaattgaaa agtcgcccat ggcaaaaaat
    30181 acctggggtc cctgataacc cgcagaggac attagccgct gcatattctg tattgttcgt
    30241 tctgaaaaag gattatgttc tacgattatt cttgtaggtt gaggtccttc accacgaaaa
    30301 cggggtaacg actctgggag acggaccagg cgattgcgag aggcctgcat tatttgtaat
    30361 gccgccggga ggttttccgg tagattactc aatgcgttac gggaaacgtc cagcgttgtt
    30421 atcgtgggag gtagtgtttc aggcagaaca gtaatctgat ttttacttac atccaggaac
    30481 tgtaattctg gtggtaacga tgcgggcaga ctggttaaag cattttcgcc ggcctccaga
    30541 ttcttcaggc ccggcggcaa tgtttcaggc agagcggtta acgaattact ctgcacattc
    30601 aaatgggtaa tccctgacgg aagatgttct ggcagtgtcc ttatgcggtt atcataaacg
    30661 ctcaggtacc gaagttcctc aggtagattt tcaggtaagg aactaatttt attatgaaaa
    30721 agatccagcg attgaagcgc tgaaggcaaa cgttccggca attcagtaat acggttaatg
    30781 ctcagctcca ttttctgtat ggtatccggt aacgtggcag ggatactggt tagctgatta
    30841 ctgctggcat acagggtctt tatatttccc tgtaaatttt ccggcaaact tttcagttca
    30901 ttgttatcga gtatcagagt agttatctgc tcaggaatac aggcgggtat agtggtaagt
    30961 cctaatattt tcagacggag ttccgtctta ttatttttca ggcagtcacg catccgttgt
    31021 acggcttctt cacgatttgc tgcctcttcc gctggcgccg cttttaccta ctcagaccag
    31081 attaactcat aattcacagt atctttggag ccggaagcgc tactcgcctg cttgctttct
    31141 gtcacacggg tataggtgac tgacttcccc cctccctcaa cggtatagcc ttctgtatta
    31201 aaaactatag acagaatttc ctgactattt tcactcaaaa tacagtattg gtctgcccct
    31261 cctctactat actgaatatt atccgcatac gccgggaaag ctaacatcct taaacattca
    31321 aacttgcttt tgatctcttc tggcgaggcg gtttcaggtg gatgacaaag ataagcgatt
    31381 cagctttgtg cttcaacctg atgttctgaa gagaaaaagg cacttatttt attccatatc
    31441 tcttctttta aaggcacctc tgttgatgcc tcattgctaa tactttgatg ccttgccgta
    31501 gattgtatat tagtaatatt aaacatattt tccctacctg atctgaacgt aacctaaagt
    31561 aacagataag gatattctca actttaaaca agaggccata gtcgtcatta tttcggacaa
    31621 atcattcagt atttgcagcg cttgacttat aaatgctcgc gcttccatca cctctttttt
    31681 aagtagaatg atgtaatctg ttgccatgac acgctttcaa cgaactcaca taagattaaa
    31741 atgacgatca tgaggatagc tataccgata atacggggcg ttttttttca tagccgagga
    31801 gagagggaaa attagcgttg ggttcagcct caacgctaat tttcttcagt tgtgattaaa
    31861 ctagctaccc cattgatgtt ttgacttttt cgacaatctc gttagtcaaa gcctgtcact
    31921 gtttttcatt cctgactgac ttagccctga ctattgcact gaaattctca aaagcgagcc
    31981 atggtaacga tgactcgctg gcgatcgaca cattgtcagg acgccgcgat aaacaactcg
    32041 cgtaactggt gcaactggtc gcgaatttgc gcggcttctt caaactccag attttgcgcg
    32101 tgctgcatca tttgctcttc cagttcatga attttctgct gcaacgcttt cggcgtcata
    32161 tccagttcga caattccggc ttttgccgta gaacggccct tgcctttccc cttcgctttg
    32221 gttttcgcaa tgttctgccc cagcgccagg atgtcgacca cttttttgtt cagcccctgc
    32281 ggagtgatac cgtgctcttc gttgtacttc tgctgcttct cgcgacgtcg ctcggtttcg
    32341 ccaatcgcct tcgccatcga cggcgtgatt ttatcgccat acagaatcgc tttaccgtta
    32401 acgttacgcg ccgcgcgccc tatggtctga atcagggagc gctcggagcg caggaagccc
    32461 tctttgtcgg cgtccagaat cgccaccagc gagacttccg gcatatccag cccttcgcgc
    32521 agcaggttaa tccccaccag aacgtcaaac tcgcccagac gcaaatcgcg gatgatttcc
    32581 atgcgctcca cggtatcaat atctgagtgc aggtaacgca cgcgctcgcc gtgctcttcc
    32641 agatattcgg tcaaatcttc cgccatccgt ttggtgagcg tagtgacaag gacacgctca
    32701 ttaatggccg cacgctgacg aatttcggac agcagatcgt ccacctgggt cgccaccgga
    32761 cgcacttcaa taatcgggtc cagcagcccg gtcggtcgca cgacctgatc caccacctca
    32821 tcaccagatt tttccagctc atagttgccg ggcgtggcgg aaacatagat agtttgcggc
    32881 gctaaggctt caaactcctc aaacttcagc ggacggttat ccagcgccga aggcagacgg
    32941 aagccatact cgaccagcgt ctctttgcgc gcccggtcgc cgcggtacat gccgcctatc
    33001 tgcgggatgg tgacatgaga ctcatccacc accagcagtc cgtcggcggg cagataatcg
    33061 aacaaggttg gcggcggttc gcccggcccg cggcccgaca gaaagcggga atagttttca
    33121 atgcctgagc agtagcccag ctcgttcatc atctctaaat cgaactgcgt gcgctggctt
    33181 aatcgctgct cttcaagcag cttattattt gccagcaaga ccttacgcct gtccgccagc
    33241 tcatctttta tctcttccat cgcctgcaga atacgctcgc gcggcgtcac gtagtgcgtt
    33301 ttgggataga tagtataacg tggcaccgtt gactctacct gcccggttaa cgggtcgaac
    33361 agcgacaggc gttccacttc ttcatcaaac agctcaacgc gtagcgcaat gtcgtcagat
    33421 tcagccggga agatgtcgat cacttcgccg cgcacgcgaa aggtaccacg ctgaaaagct
    33481 tgatcgttac gggtgtattg caattccgcc agccgacgca aaatcgcgcg ctggtcaatc
    33541 agcattccca ccgtcagatg cagcatcatt ttcaggtaga gatccggatc gcccagaccg
    33601 taaatcgcgg acacggaagc caccaccacg acatcgcgtc gctcaagcaa cgctttcgtt
    33661 gccgacaacc gcatttgctc aatatgttcg tttaccgaag cgtctttttc gataaacgta
    33721 tccgaacttg gcacatacgc ttccggctga tagtagtcat agtaggagac gaaatactcc
    33781 accgcgtttt ccgggaaaaa ctctttcatt tcgccgtaga gctgcgccgc cagggtttta
    33841 ttgggcgcaa gcaccatcgt tggccgctgc aagtccgcaa tgacgttggc gatggtgaat
    33901 gtcttcccgg agccggtcac gcccaataac gtctgatgcg ccagcccgtc ctccagcccc
    33961 tcttccagac gacgtatagc gtccggctga tcgccagaag gtttaaaagc ggaattcagt
    34021 ttgaacggtt tactcatgag cggctacctg aaggagtgag cgggcaggga tgtaatttta
    34081 ctctcgacgg tgaatattgc caataaaaaa tactggatga aaaaacagta acactccagt
    34141 gtataatggc tatcggcaga taccccacgc tatttagagg taaaacatag acagtcgcgg
    34201 ggtaaaattc cagcagtgtg ctggttatcc ccagaccaga gtctttttta acatttgtca
    34261 agtcggatga tgaaagtttt atgtcaacgt atcccccttc ctttacaacc attgatttta
    34321 tataacttgc tgtctaaaaa gggatatttt ctcaagccgt ctttcgcgcc aatttagtcg
    34381 caggccgcgt cgcctctcgc ttacgttgtg ttttctaact ctaatacaca aggttatcca
    34441 caggaatagt ggataactgc ttccagcccg tatcccctgc cgcctggcaa aatcagcccc
    34501 tgacgttttc gccgggcgat aaaaaaaaat tatcgctatt tttggcagat tattggctaa
    34561 cgagaaggca aaaattgagg cgtagacgct cacattttgc acatttttag catggcgacg
    34621 tcaggagggt ctggcgaaag aacagcagga tcgtctgatc ctgcaagaag gcggttttta
    34681 agcgcggtca ggcgcgttcc aaggggctaa ggtccagata ctgtcctgtc gccgcctgcg
    34741 atggagaaac gcccagccac gggatttccc ctaacagcgg ggccggtatg acgcggcgaa
    34801 gcgtcgcgag atattcacca tgacgcgcgc ctggcggctg catgtcgttg gctatccatc
    34861 cgacaagcgg taatccggcc tgttctaccg ccagcgccgt cagcatggcg tgattaatac
    34921 agcccagctt gacgccaaca accagaatca ccggcagctg ctccgtctgt acccagtcgg
    34981 caaacgtcag cgtggcagag agcggtgtaa accagccgcc cgccccttct gtcaacaccc
    35041 agtctgcctg cgcctccagc gttcgtaatc cgcgtgataa caccgccgcg tctatcgccc
    35101 ggccttcgtc ggcgctagcg atgtggggag aagtaggctc ggcaaaagta taaggattga
    35161 tagcggaata aggttgcggc aggctgctgt tacgctgcaa ggccagggca tcgctattgc
    35221 gtagcccgtc ggttgtcatt tcgctgccgg aagcgacggg cttatagcct acggtttgat
    35281 aacctaactg cgttgcggcc tgcaataagg cgcaactggc gaccgtttta ccgacttcag
    35341 tatcagtacc ggtcacaaaa tagcgtttag tcacgttcaa tcactcccat aaaaaggtgg
    35401 tacgtcagca gatatttccc ctgccgctgc ggccatgcca gttgaatctg tctaagccgg
    35461 gcgcgggtta atacatccgt ctcccgccct tcatgaagat gggtggcgcc aatgcctttg
    35521 agcgaacgca tcgcgctcag ggcatcctca aaccacaatg tcatcgcctg agtatgacga
    35581 gacgcccgcc agccgcgtag cgcgtggtca atggcctctt ccggcaaaaa gctattcgcg
    35641 tgagcgcgat tatcgacggc ctgccatgcc tgacgcagct ccggcaacga cccctggcac
    35701 aaggtggtaa acgccaccac gccgccgggc cgtacaaccc gatacaactc gctcaacgca
    35761 tcgcgtaaat cgccgcacca ctggaccgcc aggttgctcc aggccaggtc aaaaacttcg
    35821 gcgtcatggg gaatcgcttc gatatccgcc agcaaatagt gatgcgccgc ctgacgatcg
    35881 cgagcctgtt gcagcatcgg cagcgaaaga tccagggcgg tcacttcgct cccccgctct
    35941 cgccagtaac gactcatacg tccggggccg cagcctgcgt ccaacacact ggcaaactgg
    36001 cggcctgtca acagcgtcag cagcgcatcc gcgctgtgtt gctgtaaaga ggcgtgctgt
    36061 tcgtattgcg atgcggcccg gccaaacgcc gccgcaatag cctgcttatt cacctgcgcc
    36121 atgcagcacc tccagcagac ggtctatatc gcacgcttca tgcgcctgcg ttaacgttaa
    36181 gcgcaggcgc gccgtaccga caggcaccgt cggcggacga atcgccgtcg cccagcatcc
    36241 ttgttgacgc agcgcctccg ccaggcgcaa tgcacggctg ttatcgccca cgattaacgg
    36301 ctggatggcg ctatgggcat tcagtagcgt aaatcgggac gcgttaacgc cggcccgaaa
    36361 gcgctgaacc agagcggcga gtttttcgcg ccgttcacga ccttcatcgc tacggatcac
    36421 cgccagcgag gcgcttaacg cctgcgcctg ggcgggcggc atactggtgc tgtaaaccag
    36481 atgacgggcg aattgcagca gataatctgc gacgctttcc gagcagagca ccgctgcgcc
    36541 gctgacgcca aaccccttac cgaaagtcac caccagcaac tcaggcttca ccccccgctg
    36601 ccagcaggtg ccccgcccct catcgccagt cacgccgatg ccgtgcgcat catcaaccaa
    36661 cagccaggca tgatgcctgc gggcaatgtg ctggatttcc gccagcggcg cgctgtcgcc
    36721 gtccatgctg tatacacctt ctgtcaccac cagttgctga cccacgcagg gcgattgcag
    36781 taaacgcgac agatgctgcg tatcgttatg gataaagcgg cgaagctgcg ccggactcag
    36841 attagcggct tccagcaggg aagcatgact caacctgtcg gccacaatcc ggtcattttt
    36901 tttcattaag gcggtaatga ccgcctgatt cgccgcaaag ccagagataa acagcagcgc
    36961 gcgtggatat cctaaccatt gcgccagttc ctcctctaac gcctggtgcg ccacggaata
    37021 accgctgata tgacccgacc cgccgctgcc gacgccaaaa cgcgtcgctg cctgttgcca
    37081 ggcgcgaata atctgcggat gttgacttaa gccgaggtaa tcattgctgg aaaagttaag
    37141 atactgtcgc ccgttcgcta ccagccagcg tccggcgccc tgcgatacca catagcggcg
    37201 gcgcaacgta tccgtcgccc gacgcgccgt cagcgcatcg tcgacgcgtt gttgccaact
    37261 cataaggctg ccgcgttgta ataatcatcg gtgtcaggcg tcatcagcgt ctgctccaga
    37321 cgttgctgct gctcgttatc gcccgccagc accctggtct gctgcggatt cagccccagc
    37381 ttacggaata actgcagatc cttgtcctct gccggatttg gcgtagttaa caatttgcag
    37441 ccatagaaaa tcgagttcgc cccggccata aagcacatcg cctgggtctg ctcgttcatc
    37501 tgttcacgtc ctgcggaaag acgcacgtat gaggtcggca tcatgatgcg cgctacggcg
    37561 atagtacgaa taaaatcaaa cgcatccacg tcatcgttat ccgcaagcgg cgtgcctttt
    37621 accttcacca gcatgttgat tggcacgctt tccggcggcg taggcaggtt cgccaactgc
    37681 aacaacagtc cggcgcgatc ggtaaccgtt tcgcccagac ccacaatgcc gccggagcac
    37741 actttaatcc ctgcttcacg gactttttcc agcgtgtcga ggcgctcctg ataggtacgg
    37801 gtagtgatga tattgccgta aaactccggc gaggtatcga ggttgtggtt gtagtaatcc
    37861 agcccggcgt tagccagacg ctgcgcctgg ctctcgttca acatgccgag cgtcatacag
    37921 gtttccagcc ccatcgcttt gacgccctgt acaatcttct ccagataagg catatcgcgt
    37981 tcatgcggat tcttccaggc cgcccccata cagaagcggg tcgaaccggc gtttttcgct
    38041 ttacgggcgg agtccagtac ctgctctacc tccattaaac gctcggcttc cagcccggtt
    38101 ttatagcgcg agctctgcgg gcagtattta caatcctccg ggcaggcgcc ggttttgatc
    38161 gacaacagcg tactaacctg tacctgctgc ggatcgaaat gctggcgatg aatttgctgc
    38221 gcttcaaaca gcaattccag cagtggtttt tcaaataatt cggttacttg cgacagtgtc
    38281 cagcgtgggt ggcgagccat cgggcctctc caaaatatgt tgtttgtttt tgatatggtg
    38341 tagactcgta aacctaaatc tttttaattt ggtttacaag tcgattatga caacggacga
    38401 tctggccttc gataaacgcc atatttggca tccttacact tccatgacct cgccgctgcc
    38461 ggtatatccc gttgagcggg ccgaaggctg cgagctggtt ctcgcctcgg gcgaacgcct
    38521 gattgagggg atgtcctcct ggtgggcggc cattcatggt tataaccacc cgcaattgaa
    38581 cgcggcgatg aaagcgcaaa ttgacgccat gtcgcatgtc atgttcggcg gcataaccca
    38641 tcaacctgcg gtgaatctgt gccgtaagct ggtcgcgata acgcctgagc cgctggagtg
    38701 tgtctttctg gccgactctg gttcggtgtc ggtagaagtg gccatgaaga tggcgctgca
    38761 atactggcag gctcgtggcg aatcgcgtca gcgttttctg acgtttcgcc acggttatca
    38821 tggcgacacg ttcggcgcga tgtcggtgtg cgatccggat aactccatgc acagcttgtg
    38881 gaaaggctat ctgcctgaaa atctgttcgc gccggcgccg caaagccgga tggatggcga
    38941 atgggatgaa agcgacatcg cgccatttgc ccgcctgatg gccgcgcatc gccatgaaat
    39001 agccgccgtg attctggaac ctatcgttca gggcgcgggc gggatgcgca tatatcatcc
    39061 acaatggctc aggcgtattc gtaacatgtg cgatcgcgaa ggcattctgc tgattgccga
    39121 tgaaatagcc accgggtttg gccgtaccgg caaactgttc gcctgtgagc acgccgggat
    39181 cgcgccggat attctgtgtc tcggcaaagc cttaaccggc ggtaccatga ccctctcggc
    39241 aacgctcacg acacgccagg ttgcagagac tattagcaac ggcgaggcgg ggtgttttat
    39301 gcatggcccg acgtttatgg ggaatccgct ggcctgcgcc gtcgcttgcg ccagcctgac
    39361 gctgctggaa agcggcgaat ggcgtcagca ggtggcgtct atcgagtctc agttacgcgc
    39421 tgagttagcc cccgcgcaaa gttcgccctg ggtggcggat gtgcgggtgt tgggcgcgat
    39481 tggggtggtt gaaactacgc atccggtcaa tatggcggcg cttcaacgct tcttcgtcgg
    39541 gcaaggcgtc tggatcaggc cgttcggcaa gctaatctac ctgatgccgc cctacattat
    39601 tcgtccggat caactgcgcc gtttgaccca ggcggtcaat gacgcggtac acaatgaaac
    39661 attttttagc cattaatcag cggtaagcga tgctgcttct ggctacactt ctggtgagtc
    39721 aaaaggagag cgcatgaaac ttatcagcaa cgatttgcgc gatggagata aacttcctca
    39781 tcgccacgtt tttaacggta tgggctatga tggcgataat atttcgccgc atctggcctg
    39841 ggacgacgtg ccgatgggca ccaaaagttt tgtcgtgacc tgttacgatc ctgacgcgcc
    39901 gaccggctcc ggctggtggc actgggtggt ggtgaacctc ccggcggata cgcgcgtact
    39961 gacccagggg ttcggctcag gcctggtggc cgtaccagac ggcgtcattc agacgcgtac
    40021 cgatttcggt aaagcgggct acggcggcgc ggcgccgcct aaaggggaaa cgcaccgcta
    40081 tatctttacg gttcacgcgc tggacgtcga gcgtcttgac gttgatgaag acgccagcgg
    40141 cgcgatggtc ggctttaacg tgcatttcca ttcgctcgcc agcgcctcga taacggcgat
    40201 gttcagttaa acgctgtgtc ggatggcggc ataaacgtct tacccttcca acgggttggg
    40261 taagccgaat acgtgccgcg ccatccggca acattcacat aaagtccggt accagacgct
    40321 gtaacgcgcc ttgcgccagc agcgtcgtcg cacactcaat atcgggcgcg aaaaaacgat
    40381 cctgcgtata gtgcgccacc cgctcgcgca gtgtctgccg cgcctgttcc agtaacgggc
    40441 tggaggttaa cccttcccgt aaatctatcc cctgacaggc agccagccac tccacggcaa
    40501 tgacgccgcg ggtattcgcc gccatttccc agagtcgccg tcccgccgcc ggggccattg
    40561 agacatgatc ttcctgattc gccgaggtcg gcaggctatc cacgctgtgc gggtgcgcca
    40621 gcgctttatt ctcgctggca agcgccgcgg cggtgacctg ggcaatcata aaaccggaat
    40681 taacgccgcc atttttcacc aggaacggcg gtaactgcga catatgttta tccatcatca
    40741 gcgtgatgcg ccgctccgat agcgcgccga tttccgctat cgccagcgcc agattatccg
    40801 ccgccatggc aaccggttca gcatggaagt taccgccgga gatcacctcc cccgcctcgg
    40861 caaagaccag cggattatcg gacaccgcat tggcctcagc cagcagtacc tctttcgtct
    40921 gacgtaactg ggtcagacaa gcgcccatta cctgcggctg gcagcggagg gaatacgggt
    40981 cctgaacttt atgacagtgg tgatgtgatt cagcaatggc gctggtatcg gtcagcagat
    41041 gccggaacaa ccgcgcgacg tcaatttgcc cctgttgtcc gcgcgcggca tgaatgcgcg
    41101 catcaaaagg acggcacgat cccagtacgg cttcggtagt cagcgcgccg cagacgacgg
    41161 cggaggcaaa taattcctgt gcctcaaaca aaccgcgcag cgcgaaggcc gtcgacgcct
    41221 gggtgccgtt aagcagcgcc agcccctctt tggccgccag cgcgacaggt tccagtccgg
    41281 ccttttttag cgccgcctgc gccggaagcc attcgccctg ccagcgcgct tttccttcgc
    41341 caagtagcgt cagcgacaga tgcgccagag gcgctaagtc gcccgacgcg ccaaccgacc
    41401 cttttgccgg aatcagcgga tacacgccgg cattcaccag agcgatgagc gcctctatca
    41461 cgctcaaccg aatcccggaa aacccgcgcg ccagactatt gattttcaat accatgatca
    41521 gacgcaccat cgcgtcatcc agtgggtcgc ctacgcccgc ggcgtgagac agcaccaacg
    41581 atcgctgtag attttgcaag tcttcatcag cgatgcgcgt ctgcgccagc aggccgaaac
    41641 cggtgttgat gccgtaggcg gtacgccctt cggcaacaat atcattgacg cacgcaacac
    41701 tggcgttaat gccgtcaatg gcgctggcgt ccagccgaag ctgtaccgga tgacgccaga
    41761 catcgtacag ttgagagagg cttaactgcc ccggagtgag tgtcatggtg ttcatatcag
    41821 cctttcccct gcgtcgccgc aaccatcggt aaattcagac cttgctcaac agcgcattcc
    41881 accgcgagat catatccggc atcggcatga cgcatgacgc ccgtcgccgg atcgttgtgt
    41941 aacacgcggc gaatacgcgc ggcggcctcg tcagtgccat cacagacaat caccataccg
    42001 gcgtgttgcg aaaaacccat ccccaccccg ccgccatgat ggagcgatac ccatgtcgcc
    42061 ccgctggcgg tattcagcaa cgcatttaac agcggccagt cggaaaccgc gtcggaaccg
    42121 tcgcgcatcg cttcggtttc acggttaggg ctggcgacag aaccggaatc caggtgatcg
    42181 cggccaatca caatgggcgc ggatacctcg ccgcaacgca ccatttcgtt gaacgccagc
    42241 cccagttttt gccgccactc caagcctacc cagcagatac gcgccggtag cccctgaaaa
    42301 tgaatgcgct cacgcgccat atccagccag tgatgcagat gtttatcctc agccactatc
    42361 tctttgactt tggcatcggt tttatagata tcctgcggat cgccggacag cgccacccag
    42421 cgaaacggcc cgatgccacg acagaacagc ggacgaatat aggctggcac aaatcccgga
    42481 aaatcaaagg cgttttccac ccccatctct ttcgccatct ggcgaatatt gttgccatag
    42541 tcaaaggtcg gcacgcccat tttactgaac gccagcatcg cccgaacatg cgccgccatg
    42601 gaacgtttcg ctgcctgcat cgtcccccgg ggatcggatt gcgcgttttt ctgatactcc
    42661 tcccagcacc agccggaggg caaatagcca tgtagcggat cgtgggcgct ggtctgatcg
    42721 gtcaccaggt ccgggcgcac gccgcgatta accagttccg gcaggatatc cgccgcgttc
    42781 gcgcacaggg cgacggacac ggctttcccc tcgcgggtgt agcgcgtaat gcgggccagc
    42841 gcgtcatcca gcgtggcggc ctgctcatcc acgtagcgag tacgcagacg aaaatcgata
    42901 cggctttgct ggcattcaat cgtcagcgaa cacgctccgg ccagcgtcgc ggctagcggt
    42961 tgcgcgccgc ccatgccgcc cagcccggcg gtcagcgccc agcgtcccgc cagcgtgccg
    43021 ttatagtgct gacgccccgc ctcgacaaag gtttcgtatg ttccctgcac gattccctga
    43081 ctaccgatat agatccagct tccggccgtc atttgaccgt acatcgccag ccctttcgca
    43141 tccagttcgt taaagtgttc ccatgtcgcc cagtggggaa ccaggttgga gttggcgatt
    43201 aatacccgcg gcgcgttgtc gtgcgtttta aatacgccga ccggtttgcc agactgaatc
    43261 agcaacgttt cgtccgcctc cagccgggtg agcgcatcaa caatagcgtc atagcattcc
    43321 cagttgcgcg cggcgcgacc aatcccgccg tagaccacca gctcatgcgg attttccgcc
    43381 acgtcaggat cgagattatt cattaacatc cgcagcgggg cttctgtcag ccagcttttc
    43441 gccgttaata ccgtgcctcg gggcgcgcgg atagtctgct gacgatactt gctttcaggc
    43501 atagcaatga ctcctcatta ttatcggtct gccatcgcca aataacgcta aaacgccact
    43561 atcaggcacc gccgcagacc cacagataag aatcagacat atacttatct atacaagtaa
    43621 gcacaagaat agaattaaca aaaacgatac aattttgtta tattgtgtca gcaatcacgt
    43681 tttccggcag cagccgctca ggagataaat cgtccctgta gccggtagcg cgacccgggg
    43741 aaaagtaagc gggcgtgaga aacaatccgc gacgcggacc aggttgtacg acgaatgagc
    43801 agacaaggct catgctcttt gatagttaac cacgcgcact cttgcgccgt ggcgcgcacc
    43861 gcctccacaa tatgttcccc ttccgttagc ggcgcgatcc gcgacaaata agcgtgcggc
    43921 gtggtctgac ggtaatcctg cgtcaggtaa tccacggcaa tatccgcatt cacgcagcga
    43981 tcttcaattt gtaccggcag atcgttttca taatgcacca tgatggaatg gaaaatgaca
    44041 tcactctcat tgacgttgag agcgctggcc tggatggcgt ttgcccgcac acgctccagc
    44101 gtgagcacct cacaacgatg ctgatgatgg cgggcggcaa tctcctcggc gatactgcgg
    44161 acttcaaaca gtgcggactg gcctttcggt tcggcgacaa acgtccccac gccctgtaaa
    44221 cgcaccagcc acccttcatc cgtcagctca cgcagcgccc ggttgatggt cattcggcta
    44281 aagccatact gagcgaccag ttcagcttcc gacggaatgc gatcgtgcgg ctgccagacg
    44341 ccgccggcta tttttttaca gatgtcctgt ttcaccgttt cgtaaaaagg cgcaggcgca
    44401 gaacgggagc gggatgaata catgcgtgaa gccttcctta tgcggataat gttttccgga
    44461 tgacagatta acgccaccag tgcgcgattt gccagccaag ccgcgccgcc acgcgcgccg
    44521 ctgcgccatc ttcatcaaag cgtggattaa attcaaccag atccgccgcc tgtaattttc
    44581 cgctgcggca aaccggctca attaaacgca gaacctgtat cagcggcacg cccagcgctg
    44641 cgggagcgga gacggccggc atttcccaga caggcaatac gtcgagatcg atagtcagat
    44701 aaattttatc caccttgtca ataaactgcg tcatctgcgc cagcgcgtca tggcagtcca
    44761 gatcctccac cacggtaaca ttccgccact gcgcttcccg ccacaacgcc tgcgtattcg
    44821 ccgcacggct cacgccgaaa caagcataat gaaacgcgcg gctctgcgcg tcgcatagct
    44881 gcgccagttg acgaaacggc gtcccggatg ttgcccggtc ggtctgacgg agatccagat
    44941 gcgcatcaag attaatgatc cctacgcttt cctgcgcaaa cgcgtccagc acccccgcgc
    45001 cgtgtccaaa cgcggtttca tgcccgccgc ccattaccag cgtgcgcatc ccggcccgca
    45061 gacagcggct taccgcatcg cgcaaggcct gctgcgcgcc ttccagatcg ggcgtcggcg
    45121 caacccaatt gcctaaatcc accagccgtt catgtccctg atggctggcc atattcgcca
    45181 gcgctttacg caacgcgtcc gggccgcctg ccgcgccggg acggcctgaa ttgcgtttta
    45241 ccccctcgtc gcaggcaaat cccattaacg cgatcttttg ctgccagttt tcggggaaaa
    45301 aggcctcgct gcgcgtgacg gtctgaaaca gacgccgcgc atccggcgct tctatactgt
    45361 catcgcgccc ctgccagagc gccggagaag ccggatacca ttgcgtcatg agatttgtcc
    45421 tctgtatacc cgctgatata aagggttacg ccccggctca tacacaatct ctaccggctg
    45481 ttcagcatcc cacaccacaa aatccgcccg gtagccggcc ctgatctgcc catgcgtcgc
    45541 ctgtcttccc agcgcgcgag cggcatggcg cgtaacgccc gaccatgcct cttccggcgt
    45601 cagaccaaac tgtacgcagg ccatattcat cgccagatgc aaactgcaaa acgggctggt
    45661 gccgggattg aaatcgctgg cgacggcgac aggcacctga tagcggcgca gcagttcaac
    45721 cggcgggcgc tgcgtctcgc gcagaaaata aaacgcgccg ggcaacaaca cgccgacagt
    45781 accgccgtca cgcatcgccg cgacgcccgc ttcatcaaga tattcgatat gatccgccga
    45841 taaaccctga taacgactca ccagctgcgc gccgcccaac agcgaaagct gctcaacatg
    45901 gcctttaacg ggaataccta acgccttcgc cgtctgcaac acgcgctcac tctgggccac
    45961 attaaagccg acgctctcgc aaaagaggtc taccgcatca aataaccctt tttgccagag
    46021 ctgcggaatc atcgtctcgc agaccagagt gatgtagccg tccgggtcgt cacgatactc
    46081 cgctggcgta gcatgagcgg ccaatagcgt ggggctaatg tcgatagcgt tttcggcagc
    46141 aagttttgca gcgacgcgca acagcttttc ttctgtcgcc agctccagac catagccgga
    46201 tttaatctcc agcagcgtaa cgccttcgct ggcaaggcgc atcatgcgtt cgcgcgccag
    46261 caggtagagc gtctcctccg cacaggcgcg ggttgctgat accgtcgcgt taatgccgcc
    46321 gccctgagcg ctaatatgct ggtatgacgc gccgttaagc cgctgctccc actctgcggc
    46381 gcggttaccg gcaaacacca gatgcgtgtg gcaatcgata agtcccgggg ttaccagtcg
    46441 tccctgcata tcatggatat tgtccccact gacaggaagc tgcgtctctg gcacgatatc
    46501 gcaaatatgc ccttcgcgta caatcagcgc ctggctatcc accagcccgt acggggcttg
    46561 ccgctgcggg tccattgtcg ccagcctgat gtttcgccag acagtatcgc ccggtaaaag
    46621 ttgccgcatt cctgtcgctc tcttgcctgt catgagttgt atagacattt attttctttc
    46681 tgctccggat tgtcaactca aagcgcgaaa gttgttgctt aattgtgata aaactatctg
    46741 atgctacagg tgtttccagc ctgaaaagga actttttacc ttttcgcctt cccgtttcgt
    46801 tcaacttagt ataaaaaagc aggcttcaat ggatgtcatt taactttttc aagcccggag
    46861 caacctgtga atacattatc ggtttcccgt ctggcgctgg cactggcttt tggcgtgacg
    46921 ctgagcgcct gtagctctac gccacccgat cagatccctt ccgatcaaac cgcgcctggc
    46981 accgcctcgc gccccattct gtcggcaaat gaagcgaaaa acttcgttgc tgcgcgctat
    47041 tttgcctccc tgacgccgaa taccgccccg tggtcgccgt cgccgattac cctgcccgca
    47101 cagcctgact ttgtggtggg gccggcaggt acgccaggcg ttacgcacac ctcgattcag
    47161 gccgcgatcg atgcggcaat ggttaaacgc acgaacaaac gccagtacat tgctattatg
    47221 ccgggcgact atcaggggac cgtgtatgtt cccgccgcgc cgggaagtct gaccctgtac
    47281 gggaccggtg aaaaaccgat cgatgtaaaa attgggatgg cgattgatgg tgaaatgagt
    47341 gtcgctgact ggcgccgcgc agtgaatccc ggcgggaaat atatgcctgg taaacccgcc
    47401 tggtatatgt tcgataactg ccaaagcaaa cacgccgcga cgatcggtgt aatgtgttct
    47461 gccgcgttct ggtcgcagaa taacggtctg cagctacaaa atctgaccat cgagaacacg
    47521 ctgggcgaca gtgtcgatgc cggaaaccat ccggcggtgg cgctgcgtac cgatggcgac
    47581 aaagtccaga ttaacaaggt caatatcctt ggccgccaga acaccttctt tgtgaccaac
    47641 agcggcgtgc agaaccgtct gcaaaccgat cgccagccgc gtacgctggt gacgaacagc
    47701 tatattgaag gcgatgtgga tatggtttcc ggacgcggcg ccgtggtgtt cgataacacc
    47761 aacttccagg tcgtcaactc ccgcacacag caggaagcct acgtcttcgc cccggcgacg
    47821 ctgtccaata tttactatgg ctttttggcg atcaacagcc gctttaacgc ctccggcgat
    47881 ggcgttgcgc agcttggccg ctcgctggat gtcgacgcca acaccaacgg tcaggtcgtg
    47941 atccgcgaca gcgtgattaa cgagggcttc aacgttgcca aaccgtgggc cgacgcggtc
    48001 atctcgaaac gtccgtttgc tggaaatacg ggaaccgtgg atgacaaaga cgaggtgcag
    48061 cgtaatctga acgacacgaa ctacaaccgc atgtgggaat acaacaaccg cggtgtaggc
    48121 agtaaagtag tgacggaacc taagcagtaa tcgccgttcc ggttcaggct tataaacggg
    48181 ccgccgcagc agatgtggcg gcccgtggtt ttactgcaag cgatgtttat tgaaattaat
    48241 caggcatcct gccctggtga gctccagccc gccgccctcc ggcacacagc gctttagtac
    48301 gcgttcacca caacccacat tggcccctgg ccgacggcat aacggccttt ttccgtcagc
    48361 aacccctgag tgcccgtaat ttcatagacc gcgatatgat gtgatttttg acccgcagca
    48421 atcaggtatt tcctgctgtt gtcgatatta aagccgcgcg gttgggcttc cgtcggctgg
    48481 aagccttcaa cgctcagtac gctgccatct tcggagacac taaagacggt aatcagactg
    48541 gcggtgcggt cacaggcata cagatgccgt ccatccggcg taatatgaat atccgccgcc
    48601 cagcgggtat cggaaaaatc ggcgggcatc atatccaggg tttgtacgca ctctatctcg
    48661 ccatgcggat ttttaagctg ccagacatcc accgaactgt tcagttcatt gacgcaatac
    48721 gcatattgtc gattcgggtg gaagaccata tgacgcgggc ctgccccttc aactgtattt
    48781 acttccgccg gctcctgggc caccagatgg ccgtcatcgc ttagcgtaaa cagacaaatg
    48841 cgatcctgtt ttagcgcagg cacccacagg gtacggttat ccggcgtaat atttgccgag
    48901 tggcagccgt ccagcccttc caccacatcc accagctcaa ccggcaggcc atcctgtaag
    48961 cgcgtcacgc tgacattacc ggcgttatac gatccgacaa agacaaaacg accatgatga
    49021 tcggtagaaa tatgggtcgg gctacccggc agggcggatt cggcggcaaa cgtcagcgcg
    49081 ccatcatccg gcgcaatacg atacgccagg acacgaaact ccgggcgcac gccgacatag
    49141 aggtagcgtt tatccggact gaccaccatc ggctgaacct gaccgggcac atccacgacc
    49201 tgcaccagcg tcagcgtccc ttcgtggttc aggctccaga cgtgaatttg ctgactctca
    49261 gggctggcgg tatagactgt ttgtttcatg aatactcctt tgcatatggc atgtagctgc
    49321 aataacagga cacagcttaa cgtagtcgct tttgacggcg aatgctgaat tcagacgcag
    49381 aattttgtct gcttaccgtc ccggtgtacc atgccgacag acggaattat tactcttaat
    49441 ctggaaaaaa ttatgactgc acgcgtgatt gccctcgatt tagacggaac attattaacc
    49501 ccgcataaaa ccttactccc ctcctcgctt gaagcgctat cacgcgccaa agaggcgggc
    49561 tttcaactta tcattgtcac tggtcgccat cacgttgcta ttcatccttt ttatcaggcg
    49621 ctggcgctgg aaacacctgc tatttgctgc aacggcacct atttgtatga ttatcaagct
    49681 aaaactgtcc tggatgccga tcctatgccc gtggataagg cgttgcagtt gattgattta
    49741 ctggatgagc atcagattca cggcctgatg tatgttgatg acgctatgct ttacgaacac
    49801 ccaaccggtc acgtcgtgcg tacctcccgg tgggcgcaga ccttgccgcc ggagcaacgt
    49861 ccgaccttta cacaggtctc ttcgttggcg caggcggcgc gcgacgtgaa tgccgtgtgg
    49921 aagtttgcgc ttaccgatga agatattccc agactacagc ggttcggtca gcatgttgaa
    49981 caggcgcttg gcctggagtg tgaatggtca tggcacgatc aggtggatat cgcgcgcaaa
    50041 ggcaacagta aaggcaagcg ccttacccag tggatagaag cgcagggagg gtcaatgaaa
    50101 aatgtgatcg ctttcggcga taactacaac gacatcagta tgctggaggc ggcaggcacc
    50161 ggcgttgcga tgggcaacgc cgatgaggcg gtgaaagcgc gcgctgactt tgtgatcggc
    50221 gataacacta ccgatagcat cgccaaattt atatacaccc acctgctata gtcaggcggt
    50281 gatagaaacg cttttcacct gcgcgtaaag ccacaggcca ggcttgatat tcagctcatc
    50341 cctggcccac gggcttattc gcgcccacag cgttctgccg cctatttcaa gctggacttc
    50401 cacctgcccg ttatcgtcat aacaattcgc cacttttgcc cgtaatacgt tgcggatact
    50461 ggtctgctgc ggcggctgta gtaccagcga gacatccgac gcctgtatac gaatacgcag
    50521 tgtggattgc agcggctgat tgagtttatt tacccacagg tgctggtcgc caagcgccag
    50581 agcggtcatg gcataatgcg ggtgatgctc cagcacgctg actttcagaa tactgctctg
    50641 ttgctctttc ggcagccacg ggtgcataac gctgcttccc cagacttctt ccagcgggcc
    50701 aaacgcttta acctgtccat cctccagcac catgacttta tccgccaggt ggagaatttc
    50761 atcgagagaa tggctgacat acagcatggg aatattgatt tctcgcgcca gccgttgcag
    50821 gtacggcagt aattcgcgtt tacgcgggat atccagcgag gccaacggtt cgtccaacag
    50881 cagcaactcc ggggcggtga gcaatgcccg gcctatcgct acgcgctgtt tttctccgcc
    50941 ggacaggctc cccggcaggc gatcaagcaa cgcttcaatt cccagcagcg acaccagctt
    51001 atcaaactga ccggtcatgc ttttcgccat gccatagcgc aaattgccgc gtactttgta
    51061 atgggggaac aggcgcgcat cctggaaaac ataaccgatg cggcgctttt ccggcgttaa
    51121 acagataccg ttttccgcgt catgcaacac ccggccattc agcacgatgc gtccttttcg
    51181 cgggcgagtc aaaccgctga tggcattaat cagcgaggtt tttcccgcgc cggagacgcc
    51241 aaagatagcc gtgatcccac tggctggcag cgtttcgttg agggttaaac agtgcgttcc
    51301 cagcgtctgg gaaaaattaa gctccagcat ggttagcgcc ccgtccgttc acggctaatc
    51361 cgcgccagcc attcagaaat caacagcgaa atcagcgcta atacaatcga aatcacgcac
    51421 agcctcgccg ccgcgctctc cccgcccggc gtctggatca aggtatacat ggcggaaggt
    51481 atggtgcggg tttcgcccgg aatattggaa acaaaggtaa tggtcgcgcc aaattcgcca
    51541 agcgaacggg caaacgccag caccgtacca acaataatac ccggcagggt aagcggtaag
    51601 gtgatagtca gaaaaacgcg ccagcgcccg gcgcccagcg ttctggcggc ctgttcaagc
    51661 ttgatatcca ccccctccag cgccagccga atggcccgca ccatcagcgg gaaggacatc
    51721 accgccgccg ccagcacggc gccgcgccag ctaaaggcaa acgtgagacc gaaccagtca
    51781 tacagccact ggccaataaa cccgcgtcgc cccatcgaca ccagcagcag atagccgacc
    51841 accaccggcg gcagcaccag cggcagatgc aggacactat caagtaaggc tttgcccgga
    51901 aaccggcatc gcaccagtaa ccaggcaaaa aagatcccaa acggcaggct aaacagcacg
    51961 gccagggaag acactttcag gctaagaagg acagcctgcc attctggatc ggtcagtatc
    52021 attacttcgt cgtaaatcca taacgtttaa agattgccga ggcctgcggt cctttcaggt
    52081 aatcatagaa cgcgctgacg gccgcatttt tatgcccctc cacgatagcg atggggtatt
    52141 ccactttttt atgtgaatct tccgggaacg tcgccaccac gttgaccccc ttgctggcga
    52201 ccgcatcaga accgtataca atgcctaaag gcgcttcgtt acgttcgacc aacgccaacg
    52261 caccgcgcac atcctcgccc ggcgccagtt tcggttcaag cgtttgccat gcgcccagct
    52321 tttgcagcgc ttctttggca taaattcccg ccggtacgtg ttgcggatcg cccaccgcca
    52381 gacgcccgcc gttcagcaga tgaatccagt ccgttttgtt gtcgatggta aacggtttct
    52441 gctcgctggc tttcggcgct accactacca ggctattgcc aagcaatgtt tcgcgcgtcg
    52501 tggtatccac cgctttttta tcggctgcgt aatccatcca tttctgatca gcagagatga
    52561 acaggtccgc cggcgcgccc gcttctatct ggcgcgccag cgttgaagag gaggcgaatg
    52621 aggagaccac atccacattt ttctcttttt tatattctgc cgcaatgtct tgcatcgcgt
    52681 tcgttagcga cgcggcggcg aatacggtga tcttgccttc atccgccagc gcatgaccag
    52741 cgatgacgaa agataatgtc gcccctgcga ccaggcgtaa ccaggaatgc gccatctgta
    52801 actccttgtg cgtttcgtta tgtaaacaac aatataacga taatctcagg ggtttcccag
    52861 cggttattca tacccattaa cgattaaaca cagaaaatat cggcaggaaa agcaggatct
    52921 tgagtaacaa aaacgcccga ctgagcgggc gtttggggaa atcagcggtt ctgtctggac
    52981 tggtctttct gaccgatacc ggaaaaaatg ttgaacacct cacccagacc gtaaatcaga
    53041 ccgaggatga tggccatcac taccggtacc atgatgacgg cgaataccag actttttaat
    53101 aactctaaca tgagcaactc cagatatagt cctttttgta ttttaaccgc atcacacaga
    53161 aaagcactcc ccttttgtgc ggtcggcttt gcgctgacgc gcttttcagt cacaatagtc
    53221 tttttactag gagctggtta tgcaggccga aatccttctt accctgaaac ttcagcaaaa
    53281 gctttttgcc gatccccgac gtatctctct gctgaaacac attgcgcttt ccggctcgat
    53341 tagtcagggc gcgaaagacg cgggaatcag ctataagagc gcctgggatg cgataaacga
    53401 catgaaccag cttagcgaac atatgctggt tgaacgcgca acgggcggca aaggcggcgg
    53461 cggcgcggta ttaacccgct atggtcagcg tctgatccag ctttacgatt tgctgggcca
    53521 aattcagcaa aaagcgttcg atgtgttaag cgacgatgac gccctgccgc ttgacagtct
    53581 gctggccgct atctcccgct tttcactgca aaccagcgcc cgaaatcagt ggttcggcac
    53641 cattaccgcc cgcgatcgcg atcaggtgca acagcatgtc gacgtgctgc tggccgacgg
    53701 caaaacgcgg ctcaaagtcg cgctgacggc gcaaagcggc gagcgtctcg gcctggagga
    53761 gggaaaagaa gtgctgatcc tgctaaaagc gccgtgggtt ggcattaccc gggatgcagc
    53821 cgttgcgcgc gcagctgaca atcagttgtc gggaacgatc agccatatcg agcgcggcgc
    53881 ggaacagtgt gaagtgttga tggcgctgcc ggacggccag acgctgtgcg ccacgatacc
    53941 gactgcggat gccgccacgt taaaggaagg cgatgacgtg attgcctggt ttaatgcgga
    54001 cagagtgatt attgcaacgt tgtgctaagc acattgacat ccgttgccga aagacgtatc
    54061 cctgtcattc atcgctgcaa aaaatgggat gcaaaatgtc atcgttgcaa atttcgcaag
    54121 gcacgtttcg tctgagcgat acaaaaacac ttcatctgga ttcgctgacg ctcaatgcgg
    54181 gcgatagctg ggcattcgtt ggggctaacg ggagcgggaa gtcggcgctc gcccgcgcgc
    54241 tggcgggtga actgccatta ttaacaggcg agcgccagtg tcagtttacc cgcattaccc
    54301 gtctgtcctt tgaacaattg caaaagctgg tcagcgatga gtggcaacgt aataacaccg
    54361 atatgctcag tcctggcgaa gacgataccg ggcgcactac cgcggaaatt attcaggatg
    54421 atgttcacca tcctgcccgc tatgcgatgc tggcgcagca gtttggcatt tccgctttac
    54481 tcaacaggcg ttttaaatac ctttctaccg gcgagacgcg aaaagcgctg ctgtgtcagg
    54541 cgctgatgtc tgagccggag ttattaatcc ttgatgaacc gttcgacgga cttgacgtga
    54601 ccgcccgtca acaactggca caacgcctga cggcgttgaa ccaggcgggt atgaccctgg
    54661 cgctggtact caaccgtttt gatgagatcc cggacttcgt gcagtttgcc ggcgtgcttg
    54721 ccgactgtac gctggcggag accggaacga cggcagagtt actgcaacgg gcgttggtcg
    54781 ctcaactcgc gcacagcgag cgtctgaccg acgtacaatt acccgaaccg gacgaacctt
    54841 ccgcccgcca tgcgttaccc gatggcgaac cacggatcgt acttaacgat ggcgtagtct
    54901 cgtataacga tcgccctatc ctccaccacc taagctggcg agtcaatccg ggcgaacact
    54961 ggcagatcgt cggtcctaac ggagcgggta agtctacgtt gcttagcctt attactggcg
    55021 atcatccgca aggctacagc aacgatctta cgctgttcgg gcggcggcga ggaagcggcg
    55081 aaacaatctg ggatatcaaa aaacatatcg gctacgtcag cagcagttta catctggatt
    55141 accgcgtcag taccacggta cgcaatgtca ttctctccgg ctatttcgat tctatcggca
    55201 tttaccaggc cgtttcagac aggcaacgaa aactggcgca acagtggctg gatattctgg
    55261 gaatcgataa gcgtacggcg gatgccccct tccacagtct ctcttgggga cagcagcggc
    55321 tggcgctaat cgtgcgcgcg ctggttaaac atccgacagt gttgattctg gatgagccgc
    55381 tgcaagggtt ggacccgctg aaccgccaac tggtacgccg ttttgtggat gtattaattc
    55441 gccagggaga gactcaactg ctgttcgttt cccatcatgc agaggatgcg cctgcctgta
    55501 ttacccaccg gctggaattt gtaccagagg gcgaacgtta taagtacgtt tccggacgat
    55561 gcaataatta aatgtattat cagaatggcg ccgcgcgcca ttctggaacc actctccttt
    55621 tattaagaat aataataacg gtcgataagc ttactatctc ttgaatcgct gaccgcctca
    55681 ttgtcataat aatcctgaaa ttttcgacaa tgatgtcgta tgtgaataca agggattcat
    55741 tatggctttt cgttttccac aaataatact atttttactg gcagccatgt tattttgccc
    55801 cagcagttat gctgagcaaa agccgaccgc tgcgcaggaa gcgcgtaaaa ccgccgttga
    55861 ggtcgctgtt gaaggcatga gtcgcgccgc cgttgcgggt ccgacaaaga ttagtttagg
    55921 tgataaagcc acgcttaatc taccggaagg atttacctgg atacccgcaa aagaagcggc
    55981 ggtatttatg cgtgaaattg gtaactatgt tgacgatgaa tatt
//
LOCUS       DAJVKX010000010        55999 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000010 DAJVKX010000000
VERSION     DAJVKX010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 55999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55999
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.010"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(178..3381)
                     /gene="rne"
                     /locus_tag="OPY25_000588"
     CDS             complement(178..3381)
                     /gene="rne"
                     /locus_tag="OPY25_000588"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HCS0926286.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIQKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVMEMARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRTAVNAIETRQDGVRCVIVPNDQMETPHYSVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEYAERKRPEQPALATFAMPDVPPAPTPVEPAVSVATAKKDNVAAEQPAQP
                     GLFSRFLNALKQLFSGEETKTVETAAPKAEEKAERQQDRRKPRQNNRRDRNERRDTRD
                     NRARRDGGESRDDNRRNRRQAQQQNAEARDTRQQETAEKVKTGDEQQQTPRRERSRRR
                     NDDKRQAQQEVKALNREEQPVQETEQEERVQQVQPRRKQRQLNQKVRFTNSTVVETVD
                     TPVVVDEPRPVENVEQPVPAPRTELAKVDLPVVADIAPEQDDSVEPRDNTGMPRRSRR
                     SPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPEMASGKVWIRYPIVRPQETQVVE
                     EQREADLALPQPVVAEPQVIAATVALEPQASVQAVENVAVEPQTVAEPQAPEVVKVET
                     THPEVIAAPVDEQPQLIAESDTPEAQEVIADAEPVAETADASITVAENVADVVVVEPE
                     EETKAEAAVVEHTAEETVIAPAQVVEKPQDVVCVDDHNHASAPMTRAPAPEYVPETPH
                     HSDWQRPSFHFEGKGAAGGHSATRHASAPATRPQPVE"
     gene            3955..4914
                     /gene="rluC"
                     /locus_tag="OPY25_000589"
     CDS             3955..4914
                     /gene="rluC"
                     /locus_tag="OPY25_000589"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HCS0926287.1"
                     /translation="MKTETPSVKIVAIAADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLESGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKTVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDQQLTEAGTG
                     LKRLFLHAAALKFTHPGTGDVMRIEAPMDKQLKRCLEVLRSKA"
     gene            complement(4997..5581)
                     /gene="maf"
                     /locus_tag="OPY25_000590"
     CDS             complement(4997..5581)
                     /gene="maf"
                     /locus_tag="OPY25_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003836743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCS0926288.1"
                     /translation="MPRLILASTSPWRRALLEKLTIPFECAAPDVDETPMPGEAPRQL
                     VLRLAQAKAQSLAARFPNHLIIGSDQICVLDGEITGKPLTEEKARQQLAKASGSIVTF
                     YTGLALYNSASGHLQTEVEPFDVHFRHLSEAEIDDYVRKEHPLHCAGSFKSEGLGIAL
                     FERLEGRDPNTLIGLPLIALCQMLRREEMNPLNA"
     gene            5779..6300
                     /gene="yceD"
                     /locus_tag="OPY25_000591"
     CDS             5779..6300
                     /gene="yceD"
                     /locus_tag="OPY25_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HCS0926289.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLTGDAVVTVSLECQRCGKPFTHQVHTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLATVEDEIILALPVVPVHDSEHCEVSEADMVFGELPDEAQK
                     PNPFAVLASLKRK"
     gene            6352..6525
                     /gene="rpmF"
                     /locus_tag="OPY25_000592"
     CDS             6352..6525
                     /gene="rpmF"
                     /locus_tag="OPY25_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCS0926290.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            6659..7738
                     /gene="plsX"
                     /locus_tag="OPY25_000593"
     CDS             6659..7738
                     /gene="plsX"
                     /locus_tag="OPY25_000593"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCS0926291.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNANSQLTLLLVGNPDI
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGTSMRVALELVKEGRAEAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAVMGAVLAEEVVGIKNPRVALLNIGEEETKGLDSIREASLMLKTVPTINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFEPLDDGKGVNLRAHR"
     gene            7818..8771
                     /gene="fabH"
                     /locus_tag="OPY25_000594"
     CDS             7818..8771
                     /gene="fabH"
                     /locus_tag="OPY25_000594"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HCS0926292.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVETSDEWIVTRTGIRERHI
                     AAPNETVATMGFTAANRAIEMAGIDKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSIADQYVKSGVVKHALVVGSDVLARTCDPGDRGTIIIFGDG
                     AGAAVLSASEEPGIISTHLHADGRYGELLTLPNADRVNPDNPIYLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSELDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKAGQLVLLEAFGGGFTWGSALIRF"
     gene            8787..9716
                     /gene="fabD"
                     /locus_tag="OPY25_000595"
     CDS             8787..9716
                     /gene="fabD"
                     /locus_tag="OPY25_000595"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCS0926293.1"
                     /translation="MTQFAFVFPGQGSQSVGMLAEMAANYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALWRVWQQQGGKMPALMAGHSLGEYSALVCA
                     GVINFADAVRLVEMRGKFMQEAVPEGTGGMSAIIGLDDASIAKACEESAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPTADKLAVELAK
                     ITFSAPTVPVVNNVDVKCETDAAAIRDALVRQLYNPVQWTKSVEFIAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPAALSAALTQ"
     gene            9729..10463
                     /gene="fabG"
                     /locus_tag="OPY25_000596"
     CDS             9729..10463
                     /gene="fabG"
                     /locus_tag="OPY25_000596"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HCS0926294.1"
                     /translation="MSFEGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKN
                     ISDYLGANGKGLMLNVTDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIASA
                     VAFLASDEASYITGETLHVNGGMYMV"
     gene            10619..10855
                     /gene="acpP"
                     /locus_tag="OPY25_000597"
     CDS             10619..10855
                     /gene="acpP"
                     /locus_tag="OPY25_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCS0926295.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            10941..12182
                     /gene="fabF"
                     /locus_tag="OPY25_000598"
     CDS             10941..12182
                     /gene="fabF"
                     /locus_tag="OPY25_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCS0926296.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCDDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEVTEENASRIG
                     AAIGSGIGGLGLIEENHSSLVKGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADAMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKARSAKIYAEIVGFGMSSDAYHMTSPPEN
                     GAGAALAMVNALRDAAIEPAQIGYVNAHGTSTPAGDKAETQAVKSVFGDAASRVMVSS
                     TKSMTGHLLGAAGAVESIFSILALRDQAIPPTINLDNPDEGCDLDFVPHEARQVSDLE
                     YALCNSFGFGGTNGSLIFKKI"
     gene            12306..13115
                     /gene="pabC"
                     /locus_tag="OPY25_000599"
     CDS             12306..13115
                     /gene="pabC"
                     /locus_tag="OPY25_000599"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HCS0926297.1"
                     /translation="MFLINGHAQDQLAVSDRATQFGDGSFTTARIVDGNICHLEAHLQ
                     RLQVACEKLRIAFSHWSTLRQEMTMLATGHDSGVLKVIISRGSGGRGYSAMNCQAATR
                     ILSVSAYPAYYSQWRKQGITLTLSPIPLGRNPYLAGLKHLNRLEQVLIRSHLEQTDAD
                     EALVLDSEGWVTECCAANLFWRTGDIVFTPRLDQAGVNGIMRQFCLRQLAQSPFQVLE
                     VQAREEAVRQADEIIICNALMPIIPIRAYHGTSYSSRTLFQFLAPFCEHPN"
     gene            13118..14134
                     /gene="yceG"
                     /locus_tag="OPY25_000600"
     CDS             13118..14134
                     /gene="yceG"
                     /locus_tag="OPY25_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HCS0926298.1"
                     /translation="MKKLSGVFLLLLVVLGIATGVGMWKVRHLANSTLLIKNETIFTL
                     KAGTGRLALGDQLYDEKIINRPRVFQWLLRVEPELSHFKAGTYRFTPGMTVREMLELL
                     ESGKEAQFPLRFVEGMRLSDYLKQLREAPYIRHTLPDDDYATVAQALKLAHPEWVEGW
                     FWPDTWMYTANTSDVAILKRAHQKMVKAVDTVWKGRAEGLPYKDQNQLVTMASIIEKE
                     TAVASERDQVASVFINRLRIGMRLQTDPTVIYGMGTSYNGNLSRADLEKPTAYNTYTI
                     TGLPPGPIASPSEASLQAAAHPAKTPYLYFVADGKGGHTFNTNLASHNRSVQEKVLKE
                     KNGQ"
     gene            14124..14765
                     /locus_tag="OPY25_000601"
     CDS             14124..14765
                     /locus_tag="OPY25_000601"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCS0926299.1"
                     /translation="MGSNYIVIEGLEGAGKTTARDVVVETLEQLGIRNMIFTREPGGT
                     QLAEKLRSLVLDIRSVGDEVITDKAEVLMFYAARVQLVETVIKPALAQGVWVIGDRHD
                     LSTQAYQGGGRGIDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGDLDRIE
                     QESFDFFNRTRARYLELAAQDSRIRTIDATQPLDAVMRDIRATVTKWVQEQAA"
     gene            14762..15766
                     /gene="holB"
                     /locus_tag="OPY25_000602"
     CDS             14762..15766
                     /gene="holB"
                     /locus_tag="OPY25_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCS0926300.1"
                     /translation="MKWYPWLRPAYEKLVESYQAGRGHHALLIQALPGMGDEALCYAL
                     SRYLLCQQPEGHKSCGHCRGCQLMQAGTHPDYYTLTPDKGKSSLGVDAVREVSEKLYE
                     HSRLGGAKVVWIADAALLTDAAANALLKTLEEPPEQTWFFLASPEPARLLATLRSRCR
                     LHHLAPPSESYAMSWLSREVTASQEALLTALRLNAGSPGAALALLQSERWAQREALCQ
                     ALMDSLHTGDWYALLTALNHEQAPARLHWLATLLVDALKRQHGASYLTNVDADAVVAA
                     LAGPLSPARIQAILNDVCHCRDQLLHVTGLNRELVLTDLILRIEHYLQPGTLLPVPHL
                     "
     gene            15777..16574
                     /locus_tag="OPY25_000603"
     CDS             15777..16574
                     /locus_tag="OPY25_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCS0926301.1"
                     /translation="MFLVDSHCHLDGLDYQSLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYRHMRELVGKRDNVVFSCGVHPLNQDEVYDVEELRLLAAEDDVVAMGETGLDYFYT
                     PETKIRQQASFIHHIQIGRELHKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQITTDNFARLFHIDASRLSSIR"
     gene            16869..18302
                     /gene="ptsG"
                     /locus_tag="OPY25_000604"
     CDS             16869..18302
                     /gene="ptsG"
                     /locus_tag="OPY25_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HCS0926302.1"
                     /translation="MFKNAFTNLQKAGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIAAKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFVWPPVGTAIQAFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGMLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGAGYAIVYYTVFRVLIKALDLKTPGREDSTDD
                     AKAGATSEMAPALIAAFGGKENITNLDACITRLRVSVADVAKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNS"
     gene            complement(18387..20562)
                     /gene="fhuE"
                     /locus_tag="OPY25_000605"
                     /pseudo
     CDS             complement(18387..20562)
                     /gene="fhuE"
                     /locus_tag="OPY25_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460174.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
     gene            20904..21263
                     /gene="hinT"
                     /locus_tag="OPY25_000606"
     CDS             20904..21263
                     /gene="hinT"
                     /locus_tag="OPY25_000606"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HCS0926303.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDELVTAFRDISPQAPTHILIIP
                     NILIPTVNDVTAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            21266..21640
                     /locus_tag="OPY25_000607"
     CDS             21266..21640
                     /locus_tag="OPY25_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HCS0926304.1"
                     /translation="MIKGCIAVSLGLLLLTGCRSHPEIPVSDAQSLVMESAVLAAGVT
                     AEPPELTASDIQPSASSRVYNERQEPITVHYRFYWYDARGLEMHPLEAPRSVTIPARS
                     SVTLFGSANYLGAHKVRLYLYL"
     gene            21654..22292
                     /gene="lpoB"
                     /locus_tag="OPY25_000608"
     CDS             21654..22292
                     /gene="lpoB"
                     /locus_tag="OPY25_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HCS0926305.1"
                     /translation="MTKMHRYAAIAALAIFLSGCMAQRQPAPVEEVKPAPEQPAQPPQ
                     PPVVPSVPTIPQQPGPIEHEDQTGQPAPKVRHYDWNGAMQPLVSKMLQADGVTARSVL
                     LVDSVNNRTNGSLNANEATETLRNALANNGKFTLVSVQQLAMAKQQLGLSPQDSLGTR
                     SKAIGIARNVGAQYVLYSSASGNVNAPALQMQLMLVQTGEIIWSGKGAVQQQ"
     gene            22273..23097
                     /gene="thiK"
                     /locus_tag="OPY25_000609"
     CDS             22273..23097
                     /gene="thiK"
                     /locus_tag="OPY25_000609"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HCS0926306.1"
                     /translation="MRSNNNNPLTRDEILSRYFPQYRPAVAASQGLSGGSCIIAHDTH
                     RIVLRRHHDPDAPPAHFLRHHRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPD
                     ADELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRP
                     LRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYA
                     ARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG"
     gene            23108..24133
                     /gene="nagZ"
                     /locus_tag="OPY25_000610"
     CDS             23108..24133
                     /gene="nagZ"
                     /locus_tag="OPY25_000610"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HCS0926307.1"
                     /translation="MGPVMLNVEGCELDAEEREILAHPLVGGLILFTRNYHDPEQLRE
                     LVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFFALHGLEEGGRLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPAKALAMATRFIDGMHDAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPETDIRGKDMSVFRALISENKLDAIMPAHVIYRA
                     IDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERAQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRRELMDSARWKTASAQLNQLHERW
                     QEEKAGH"
     gene            24158..24700
                     /locus_tag="OPY25_000611"
     CDS             24158..24700
                     /locus_tag="OPY25_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCS0926308.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPFYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            24955..26259
                     /gene="ndh"
                     /locus_tag="OPY25_000612"
     CDS             24955..26259
                     /gene="ndh"
                     /locus_tag="OPY25_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HCS0926309.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVMDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKEHCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNDALNVTLVEAGE
                     RILPALPPRISSAAHNELTKLGVRVLTQTMVTSADEGGLHTKEGEYIQADLMVWAAGI
                     KAPDFMKEIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCARPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKAYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
     gene            26436..26975
                     /locus_tag="OPY25_000613"
     CDS             26436..26975
                     /locus_tag="OPY25_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HCS0926310.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFDRGPQYAQVISAKPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRIAGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSMQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDKD
                     PGTQIPLDGNGQLVLNNKA"
     gene            complement(27049..27684)
                     /gene="comR"
                     /locus_tag="OPY25_000614"
     CDS             complement(27049..27684)
                     /gene="comR"
                     /locus_tag="OPY25_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HCS0926311.1"
                     /translation="MTTDTTSCAKKSRGRPKVFDREAALDKAMTLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYITRFASKHEAQLFCEEKSVESALEDYFT
                     EIAACFTSTDTPAGCFMINTSATLAASSRDIARTVKSRHAMQEQTLIQFLRQHQERGE
                     IPAHCNPQALAEYINCILQGMSISAREGATFEQLMQITRTTLRIWPELLKS"
     gene            27926..28183
                     /locus_tag="OPY25_000615"
     CDS             27926..28183
                     /locus_tag="OPY25_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0926312.1"
                     /translation="MKNVKNLIAAAVLSSLSFASFAAVEVQATPEGQQKFGTISANGG
                     TNLGSLEDQLAQKAQEMGAKSFRITSVTGPNTLHGTAVIYK"
     gene            complement(28289..29071)
                     /locus_tag="OPY25_000616"
                     /pseudo
     CDS             complement(28289..29071)
                     /locus_tag="OPY25_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460185.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
     gene            complement(29219..32665)
                     /gene="mfd"
                     /locus_tag="OPY25_000617"
     CDS             complement(29219..32665)
                     /gene="mfd"
                     /locus_tag="OPY25_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCS0926313.1"
                     /translation="MPEKQRYTLPTKAGDQRQLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEIRQFTDQMVMNLADWETLPYDSFSPHQEIISSRLSTLYQLPSMQ
                     RGVLIVPVNTLMQRVCQHSYLHGHALVMKKGQRLSRDALRAQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSEQPYRLDFFDDEIDSLRLFDADTQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDAEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLVVNTGSLETSAERFQADTLARFENRGVDPMRPLLPPEALWLRVDGLFSELKRW
                     PRLQLKTDHLPEKAANTNLGFQKLPDLAIQAQQKAPLDALRKFLESFSGPVIFSVESE
                     GRREALGELLARIKIAPKRILRLDEAQDAGRYLMIGAAEHGFIDTQRNLALICESDLL
                     GERVARRRLDSRRTINPDTLIRNLAELHVGQPVVHLEHGVGRYAGMTTLEAGGIKGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEESAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVENHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     LSRFRSAKEQTQILAEAAEGKIDILIGTHKLLQSDVKLRDLGLLIVDEEHRFGVRHKE
                     RIKAMRADVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTADAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKNENELEEIKVELIDRFGLLPDPARNLLDIARLRQQAQKLGIRKLEGNEKGGTIE
                     FAEKNHVDPAWLIGLLQKQPQHFRLDGPTRLKFIQDLSERKTRIDWVRQFMQQLEENA
                     IA"
     gene            33003..34202
                     /gene="lolC"
                     /locus_tag="OPY25_000618"
     CDS             33003..34202
                     /gene="lolC"
                     /locus_tag="OPY25_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HCS0926314.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSAEHGSLNPNQMPEKAVNLQGVNRIAPLTTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQSELQPGKYNVILGEQLAGQLGVNRGD
                     QIRLMVPSASQFTPMGRLPSQRLFTVIGTFAANSEVDGYEMLVNIQDASRLMRYPAGN
                     ITGWRLWLDEPLQVDTLSQQTLPQGTKWQDWRERKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGALLGAALGA
                     LLASQLNNLMPIIGAFLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            34195..34896
                     /gene="lolD"
                     /locus_tag="OPY25_000619"
     CDS             34195..34896
                     /gene="lolD"
                     /locus_tag="OPY25_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HCS0926315.1"
                     /translation="MNKILLQCDNLCKRYQEGTVQTDVLHDVSFSIGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFSGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEIDARAREMLHAVGLEHRATHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFELLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            34896..36140
                     /gene="lolE"
                     /locus_tag="OPY25_000620"
     CDS             34896..36140
                     /gene="lolE"
                     /locus_tag="OPY25_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HCS0926316.1"
                     /translation="MASPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVNQPWTNWREALAKVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVDPKQEQQLSALPSFVQNHAWDHFKAGEQQIIIGKGVADALNV
                     KQGDWVSIMIPNANADHKLLQPKRVRLHVIGILQLSGQLDHSFAMIPLEDAQQYLDMG
                     SSVSGIALKVHDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     ILVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLLGSLIG
                     VAIGVVVSLQLTAIINGIEKEIGHQFLSGDIYFIDFLPSELHWLDVVYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            36169..37077
                     /gene="nagK"
                     /locus_tag="OPY25_000621"
     CDS             36169..37077
                     /gene="nagK"
                     /locus_tag="OPY25_000621"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HCS0926317.1"
                     /translation="MYYGFDIGGTKIALGVFDSTRRLQWEKRVPTPHTSYSAFLDAVC
                     ELVAEADQRFGVKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGGGGLVLNGKPITGQSYITGEFGHMRLP
                     VDALTLMGFDFPLRRCGCGQMGCIENYLSGRGFAWLYQHYYDQSLQAPEIIALWEQGD
                     EQAHAHVERYLDLLAVCLGNILTIVDPDLLVIGGGLSNFTAITTQLAERLPRHLLPVA
                     RAPRIERARHGDAGGMRGAAFLHLTD"
     gene            37096..37917
                     /gene="cobB"
                     /locus_tag="OPY25_000622"
     CDS             37096..37917
                     /gene="cobB"
                     /locus_tag="OPY25_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCS0926318.1"
                     /translation="MQSRRFHRLSRFRKNKRLLRERLRQRIFFRDRVVPEMMENPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARNPGLVQTFYNARRQQLQQP
                     EIQPNAAHLALAKLEEALGDRFLLVTQNIDNLHERAGNRNIIHMHGELLKVRCSQSGQ
                     ILEWNGDVMPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGSEFEEKHYGPASQVVPEFVDKFLKGL"
     gene            complement(37999..39045)
                     /gene="potD"
                     /locus_tag="OPY25_000623"
     CDS             complement(37999..39045)
                     /gene="potD"
                     /locus_tag="OPY25_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HCS0926319.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHASDNDTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLTNFHNLDPEMLNKPFDPNNDYSVPYIWGATAIGVNSDAIDPKTITSWADLWKPEYK
                     NSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYEELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMVWNGSAFVARQAGTPLEVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKEVAETIGYPTPNLAARKLLSPEVANDKSLYPDAQTISKGEWQNDVGDAS
                     AIYEEYYQKLKAGR"
     gene            complement(39070..39849)
                     /gene="potC"
                     /locus_tag="OPY25_000624"
     CDS             complement(39070..39849)
                     /gene="potC"
                     /locus_tag="OPY25_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HCS0926320.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYELLVNNDSLLQAAQHSLTMAIFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFSLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEVTILRKIILPLAMPAVAAGWLLSFTLSMDDVVVSSFVTGPGYEILPLKI
                     YSMVKVGVSPEVNALATVLLVLSLVMVIASQLIARDKTKGR"
     gene            complement(40165..41175)
                     /gene="sifA"
                     /locus_tag="OPY25_000625"
     CDS             complement(40165..41175)
                     /gene="sifA"
                     /locus_tag="OPY25_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector SifA"
                     /protein_id="HCS0926321.1"
                     /translation="MPITIGNGFLKSEILTNSPRNTKEAWWKVLWEKIKDFFFSTGKA
                     KADRCLHEMLFADRTPTRERFTEIFFELKELACASQRDRFQVHNPHENDDTIILRIMD
                     QNEENELLRITQNTDTFSCEVMGNAYFLIKDRPDILKPHPQMTAMINRRYSEIVDYPL
                     PSTLCLNPAGAPTLSVPLDNIEGYLYSEWRKGNLDEWKTQEKATYLAAKIQSGIEKTT
                     RILQHANISESTQQNAFLETMTMCGLKQLEIPPPHTHIPIEKMVEEVLLADKTFQAFL
                     VTDPSASLSMLAEIVEAISDQVFHAIFRIAPQSIQKMAEEQLTTLHVRSEQQSGYLCC
                     FL"
     gene            complement(41504..42367)
                     /gene="potB"
                     /locus_tag="OPY25_000626"
     CDS             complement(41504..42367)
                     /gene="potB"
                     /locus_tag="OPY25_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HCS0926322.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYARLLDPLYFEVLLHSLNMALIATLSCLVLGYPFAWFLAKLPEKIRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKMQTFIRIIIPLTMPGIVAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLIYWRASR
                     LLNKKVSDISD"
     gene            complement(42351..43487)
                     /gene="potA"
                     /locus_tag="OPY25_000627"
     CDS             complement(42351..43487)
                     /gene="potA"
                     /locus_tag="OPY25_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HCS0926323.1"
                     /translation="MGQSKKLNKQPRSLSPLVLLSGISKSFDGKEVISQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDAGHIMLDNQDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEIAPRVTDALRMVQLEEFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRNGVIEQDGTPREIYEEPKNLFVAGFIGEINRFDATVIERLDEQRVRASVEGREC
                     NIYVNFAVELGQKLNVLLRPEDLRVEEINDDNHIEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAISWVESWEVVLADEEHK"
     gene            43738..44967
                     /gene="pepT"
                     /locus_tag="OPY25_000628"
     CDS             43738..44967
                     /gene="pepT"
                     /locus_tag="OPY25_000628"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCS0926324.1"
                     /translation="MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEE
                     MGLVNITLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMTALAVLKGNPI
                     PHGEIKVAFTPDEEVGKGAKHFDVEEFGAQWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADEAPETTEGYEGFYHLASMKGTVDRAEMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCHITPEMKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTGKRGQ"
     gene            44971..46305
                     /locus_tag="OPY25_000629"
     CDS             44971..46305
                     /locus_tag="OPY25_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926325.1"
                     /translation="MLHIVVKRFIIYGGIFSAINFSAWSAEYTPSWSQRQQQSAACFM
                     TGDETCMTFIDDAVRLASRQYGKRSIQLVRSLLLQSDIYQWLGKPELTPQMLLRARAI
                     MKTFPAGTYPGDRADMFEHLAAFYVYGDDRHIEYSPTEQWRYEIKVDYRQRIAWQEQA
                     LTWRLKDKKTSTEALVYTLNRMRDAYSDALEERDVECDSARKAYYLAKIDAAERQWLS
                     VILRDKTWDNRERVASFLQQKADIAYNAGHISEAINALSQALKIEQTLYGTEFGEMTV
                     DSNNLAGFYAQGHHYKEAKDLYLKLIAYYQSRLTPMATVISRLRFYLPENIDLDSTSP
                     YLPLLEEYKRRQSDVSMVLYGISLLYKNNQQLEQAKDFAERAFTLDAVAYPAKMQYER
                     LQQLANIAEGLGDNAQARRYRQMSFRHRMAHSIYPGDPQYNDFAKPGGDRCG"
     gene            complement(46345..47466)
                     /locus_tag="OPY25_000630"
     CDS             complement(46345..47466)
                     /locus_tag="OPY25_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCS0926326.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFTNFIDPLSPDELAGLA
                     MESEIDSRLVSHQDGKWQVSHGPFESYDHLGESNWSLLVQAVNHWHEPTAALMRPFRA
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMRQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNSRELISGFADYV
                     LQRDLGNTYYSDPDMPSRKHPADILPQEMDKLRNMMLDLINQPAHFQQWLGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGEALVRLGGLRVLRIGDEVYANGEKIDSPHRPALE
                     ALTSHIVLTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(47547..49010)
                     /gene="phoQ"
                     /locus_tag="OPY25_000631"
     CDS             complement(47547..49010)
                     /gene="phoQ"
                     /locus_tag="OPY25_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HCS0926327.1"
                     /translation="MNKFARHFLPLSLRVRFLLATAGVVLVLSLAYGIVALVGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKISVELPENLDMQSPTMTLIYDETGKLLWTQRNI
                     PWLIKSIQPEWLKTNGFHEIETNVDATSTLLSEDHSAQEKLKEVREDDDDAEMTHSVA
                     VNIYPATTRMPQLTIVVVDTIPIELKRSYMVWSWFVYVLAANLLLVIPLLWIAAWWSL
                     RPIEALAREVRELEDHHREMLNPETTRELTSLVRNLNQLLKSERERYNKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRNEKMSVSKAEPVMLEQISRISQQIGYYLHRASMRGSGVLL
                     SRELHPVAPLLDNLISALNKVYQRKGVNISMDISPEISFVGEQNDFVEVMGNVLDNAC
                     KYCLEFVEISARQTDDHLHIFVEDDGPGIPHSKRSLVFDRGQRADTLRPGQGVGLAVA
                     REITEQYAGQIIASDSLLGGARMEVVFGRQHPTQKEE"
     gene            complement(49010..49681)
                     /gene="phoP"
                     /locus_tag="OPY25_000632"
     CDS             complement(49010..49681)
                     /gene="phoP"
                     /locus_tag="OPY25_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HCS0926328.1"
                     /translation="MRVLVVEDNALLRHHLKVQLQDSGHQVDAAEDAREADYYLNEHL
                     PDIAIVDLGLPDEDGLSLIRRWRSSDVSLPVLVLTAREGWQDKVEVLSSGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVINISPFQVDLSRRELSVNEEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTVRGQGY
                     LFELR"
     gene            complement(49808..51178)
                     /gene="purB"
                     /locus_tag="OPY25_000633"
     CDS             complement(49808..51178)
                     /gene="purB"
                     /locus_tag="OPY25_000633"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCS0926329.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADANGYLDTLVANFNEEDAARIKTIERTTNHDVKAVEYFLKE
                     KAAAIPALHDVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQVINAVKDLATQ
                     YRDIPLLSRTHGQPATPSTLGKEMANVAYRMERQFRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCIARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLHHLANKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQLIDSLALPEAEKTRLKAMTPANYIGRAVN
                     LVDELK"
     gene            complement(51182..51823)
                     /gene="hflD"
                     /locus_tag="OPY25_000634"
     CDS             complement(51182..51823)
                     /gene="hflD"
                     /locus_tag="OPY25_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HCS0926330.1"
                     /translation="MAKNYYDITLALSGICQSARLVQQLAHQGHCDADALHVSLNSVI
                     DMNPSSTLGVFGGSEANLRLGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALNTLGDRINGLQRQLDHFDLQSDTLMSAMAGIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRASLLAGIRAAVLWHQVGGGRLQLMFSRHRLTTQAKQILAYLTPEL"
     gene            complement(51910..53016)
                     /gene="mnmA"
                     /locus_tag="OPY25_000635"
     CDS             complement(51910..53016)
                     /gene="mnmA"
                     /locus_tag="OPY25_000635"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCS0926331.1"
                     /translation="MSESPKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVNGKSRLLRGLDGNKDQSYFLYTLGH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFRDFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGSEDPWYVVDKDVENNVLIVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTLRCTVKTRYRQTDIPCTINALDDDRIEVIFD
                     EPVAAVTPGQSAVFYSGEVCLGGGIIEQRLPLTV"
     gene            complement(53070..53531)
                     /locus_tag="OPY25_000636"
     CDS             complement(53070..53531)
                     /locus_tag="OPY25_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCS0926332.1"
                     /translation="MFKPHVTVACIVHAEDKFLVVEETINGKSLWNQPAGHLEADETL
                     AQAAARELWEETGITAQPQYFIRMHQWIAPDKTPFLRFLFAIKLDHICATAPHDNDID
                     CCRWVSADEILNAPNLRSPLVAESIRSYQTGQRYPLSIVGEFNWPFTEGVK"
     gene            complement(53543..53872)
                     /locus_tag="OPY25_000637"
     CDS             complement(53543..53872)
                     /locus_tag="OPY25_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1311 domain-containing protein"
                     /protein_id="HCS0926333.1"
                     /translation="MKRLLIAFALLTPLSVNAASFDCQKAQAADEKAICAHLTLNDKD
                     VEMHTKYQFLKGLFAMGSRGALQDAQQSWLKQRQQCKADVTCLTKAYNERLKQLDAIY
                     DHIDKPL"
     gene            complement(53869..54534)
                     /gene="rluE"
                     /locus_tag="OPY25_000638"
     CDS             complement(53869..54534)
                     /gene="rluE"
                     /locus_tag="OPY25_000638"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HCS0926334.1"
                     /translation="MRQLISSENTMQKTSFRNHYVKRFSSRQASKSRKENQPKRVVLF
                     NKPYDVLPQFTDEAGRRTLKDFIPVQGVYAAGRLDRDSEGLLVLTNDGALQARLTQPG
                     KRTGKIYYVQVEGIPDNAALQALRTGVTLNDGPTLPAGIEIVAEPDWLWPRTPPIRER
                     KNIPTSWLKVTLYEGRNHQVRRMTAHVGHPTLRLIRYSMGDYTLNGLDNGQWCEIAQE
                     KDR"
     gene            54706..55956
                     /gene="icd"
                     /locus_tag="OPY25_000639"
     CDS             54706..55956
                     /gene="icd"
                     /locus_tag="OPY25_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HCS0926335.1"
                     /translation="MESKVVVPVEGKKITLQNGKLNVPENPIIPFIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIRDYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYVCLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     TNDRDSVTLVHKGNIMKFTEGAFKDWGYQLARDEFGGELIDGGPWLKIKNPNTGKEIV
                     VKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMQWFEAADLIVKGMEGAIAAKTVTYD
                     FERLMDGAKLLKCSEFGDAIIANM"
BASE COUNT        12860 a        14141 c        15431 g        13567 t
ORIGIN      
        1 tcgttattga gttagtggtc atattgtcgc gcccgtagcg acgccatccg tacgtattat
       61 cccgcccgat ctcataaacg cctggagtga ctaaaagacg ccatggggtg aggcatcgcc
      121 ctgtaagagg cataaaaaaa agccgacctg gcggtcggct ttgtatcagc atttacatca
      181 ttctaccggc tgtgggcgtg tcgccggggc gctggcgtga cgtgtggcgc tgtgtccgcc
      241 tgctgcgcct ttaccttcaa agtggaagga agggcgctgc cagtcgctat ggtgcggggt
      301 ttccggcaca tattccggcg ctggcgcacg cgtcatcggc gcgctggcgt ggttatgatc
      361 gtcaacgcag acaacgtcct gcggcttttc caccacctgg gccggtgcga taacggtttc
      421 ttctgccgtg tgctccacaa cagccgcttc cgcttttgtc tcttcttctg gctcgacaac
      481 gacaacatca gctacgtttt cagccaccgt aatggacgcg tcggcggttt ctgctaccgg
      541 ttcggcgtca gcaataacct cttgcgcttc cggcgtatcg ctttcggcaa tcagttgcgg
      601 ctgttcatca accggcgcgg caatcacttc cggatgcgtt gtctcgacct tgacgacttc
      661 cggcgcctgt ggttcggcga cggtctgcgg ctcaacggca acgttttcta ccgcctgtac
      721 cgacgcttgt ggttcgagcg ctacggtcgc agcgataacc tgcggttcag cgacaaccgg
      781 ttgtggcagc gccagatctg cttcacgctg ctcttcaaca acctgcgttt cctgaggacg
      841 gacaatcggg tagcggatcc agactttacc ggacgccatt tctggcgacg cgcaggcgac
      901 ggttaacggc atcggcgatt gtgtcgggta gcgctcgtca cgatagcgac ggcgacgctg
      961 accgcttacg cgcaggtggc gcggagaacg gcgggagcga cgcggcatac cggtattatc
     1021 gcgaggttct acgctatcat cctgctccgg cgcgatatcg gcaacgacag gtaaatcaac
     1081 tttcgccagc tcggtacgcg gcgctggaac gggctgttca acgttttcaa ccgggcgtgg
     1141 ttcgtcgacg acgaccggcg tgtcaaccgt ttcaaccact gtgctgttgg taaagcggac
     1201 tttctgatta agctgacgtt gcttacggcg cggctgaacc tgctgaacgc gttcttcctg
     1261 ctcggtctcc tggacaggct gttcttcgcg gttaagcgct tttacttcct gctgcgcctg
     1321 gcgtttgtca tcattgcggc ggcggctgcg ttcgcgacgc ggcgtctgtt gctgctcatc
     1381 gccggttttc actttttccg ccgtttcctg ctggcgggta tcgcgcgctt ccgcattttg
     1441 ctgctgcgcc tggcgacggt tacgacgatt atcgtcgcgg ctctcgccgc cgtcacgtct
     1501 ggcacggtta tcacgggtgt cgcggcgttc gttacgatcg cgacggttgt tctgtcgtgg
     1561 cttgcgacga tcctgctgac gctccgcttt ttcttccgct ttcggcgcgg ctgtttcgac
     1621 ggttttcgtt tcttcaccgc tgaacagttg tttcagcgcg ttaaggaagc ggctaaacag
     1681 acccggctgg gcaggctgct cggcggcaac attatccttt ttcgccgtgg caacgctaac
     1741 cgccggttcg acaggcgtcg gcgccggagg cacatctggc atagcgaatg tcgccagcgc
     1801 aggctgttcc gggcgtttac gctcggcgta ctcttcttca gaaggcagcg ccatcgcttc
     1861 ttcgtgcagc ttcggcagca tgtagctcag ggtcggcgtt tcttcccctt tgcgtacgcg
     1921 tagcacggaa tagtgcggcg tttccatctg atcgttcggg acgatgacac agcggacgcc
     1981 atcctgacgc gtctcaatag cgttaactgc cgtccgtttt tcgttaagca gataagaggc
     2041 gatcggcacc ggaacaatgg catggacttc ctgcgtattc tctttcagcg cttcttcttc
     2101 aatcaggcgc agaatggaca gcgacagaga ttcgttatcg cgcacggtgc cggtaccgct
     2161 acagcgcgga cacacgtgat ggctggattc gcccagcgac gggctcaggc gctgacgcga
     2221 catttcgagc aggccgaagc gggaaatatg gctaatctga atacgcgccc ggtcctgacg
     2281 caccgcttca cgcaggcggt tttctaccgc gcgctggtga cgtaccggcg tcatatcgat
     2341 aaagtcgata acgatcaggc cgcccaggtc gcgcagacgc aactggcggg caatctcatc
     2401 ggccgcttcg agattggtgt tgaacgcggt ttcttcgata tcgccgccgc gagttgcgcg
     2461 ggcggagttg atatcgatag cggttaacgc ttcggtgctg tcaatgacga tggagccgcc
     2521 ggagggcagg cgcacttcac gctggaacgc agactcgatc tgcgattcga tctggtaatg
     2581 gctgaacaac gggatttcac cggtgtatag cttaattttg ctgctaaaat ccgggcggcc
     2641 caacgcggcg atatgctgac gcgccatttc catcactttt ggattgtcga ttaggatttc
     2701 accgatatcc tgacgcagat agtcgcgaaa cgcgcgtacg atgacgttgc tttcctgatg
     2761 gatcaggaac ggcgcgggac ggctttcagc ggctttctga atggcttccc agtgtttcag
     2821 gcggaagctt aaatcccact gcaacgcttc ggcggattta cccacgcccg cggtacgtac
     2881 gataagcccc atcccttcag gaagttccag gctggccaac gcttctttta actcggtacg
     2941 atcgtcgcct tcaatgcgac gggagatacc acccgcgcgc gggttattcg gcatcagtac
     3001 caggtagctg cccgccagac tgataaaggt ggttaacgcc gcgcctttgt tgccgcgctc
     3061 ttctttatcg atttgaacaa tgacttcctg gccttcgcgt aacacgtctt tgatgttcgg
     3121 gcgaccatga gcgctgtagt tagcggggaa atattcgcgg gcaatttctt ttaacgggag
     3181 gaaaccgtgg cgttctgcgc cgtaatcaac aaaagccgct tccaggctcg gttcaatacg
     3241 ggtaattttg cctttataga tgttcgcttt tttctgctcg tgtccggggc tttctatatc
     3301 cagatcgtac agacgctgcc catctacaag ggcgacgcgc aactcttcct gctgagtcgc
     3361 gttgattaac attcttttca tcgtaactta ctcattattc ttacgttgac gactaagctg
     3421 cgggcatggt gacgccttac cgggcatgaa ccgatggcct cgtgactatt tcgcgtcgcc
     3481 aacctcacgg ttatcgtcag ctcaaagagg cgcagagtgt cggttgcctg tatttcatac
     3541 ggaaacacag cgcaattatc agggaagcag cctgggcatt actctccaga gaagatccta
     3601 tctaccggta aggactgcaa cccgcagccc gctaactgtc tgaaaaatca atacgtctta
     3661 cgccattgct gcgttgatga tcggtcagac aaaatgggtt attccgctaa actttttgtt
     3721 ttaacaagtt tcggtgcgga aaccgcatca ttattccact gctaaccttg ttatagcaag
     3781 atgactttta ccatttatca cccgcttact cacagttttt tcaccagcgc gagccaatcg
     3841 ctttaataac cagcaaaacc gcagtgaaaa atgttcatcc actggcgtag acgtctctat
     3901 aagcatagaa aaatgtgtgg cgcgaatctc acaggctatt tagaatcgcc ccccatgaaa
     3961 acagaaacgc catccgtaaa aattgttgct atcgccgctg acgaagcggg gcaacgcatt
     4021 gataactttt tgcgcaccca actgaaaggg gtaccaaaaa gtatgattta tcgcatcttg
     4081 cgtaaaggcg aggtgcgggt gaacaaaaaa cgcattaaac cggaatacaa actggaatcg
     4141 ggcgatgaag tccgcattcc gccggttcgc gttgctgagc gcgaagaaga ggctgtgtcg
     4201 ccgcatttgc aaaaagtggc ggcgttggcg gacgtcattt tgtatgaaga cgaccatatt
     4261 ctggtgctga ataagccttc cggcaccgcc gtacacggtg ggagcgggtt aagtttcggc
     4321 gtcatcgaag ggctgcgggc gttgcgtccg gaagcgcgat tcctggaact ggtgcatcgt
     4381 cttgaccgcg atacttccgg cgtgctgttg gtggcgaaaa aacgctccgc gctgcgttcg
     4441 ctgcatgagc aactgcgcga aaagggaatg cagaaagatt atctggcgct ggtgcgcggc
     4501 cagtggcaat cacacgttaa aaccgtacag gcgccattat taaagaacat tctgcaaagc
     4561 ggcgaacgca ttgtccgcgt gagccaggaa ggcaaacctt cagaaacgcg cttcaaggtg
     4621 gaagagcgtt atgccttcgc cacgctggtg cgctgtagcc cggtcacggg ccgtacgcat
     4681 cagattcgcg tacataccca atatgccggt caccctattg cgttcgacga tcgctacggc
     4741 gaccgtgagt ttgatcaaca gcttaccgaa gcgggaaccg gtcttaaacg tctctttctg
     4801 cacgccgcgg cgctgaagtt cacgcatccg ggaacgggcg atgtcatgcg cattgaagcg
     4861 ccaatggata agcaattgaa gcgctgcctt gaggtattac gtagtaaagc ctgatgcgcg
     4921 ttgcttatca ggcctacaat cgtgtgatgc accgtaggcc tgataagacg catcgcgtcg
     4981 ccatcaggca gattaatcag gcattcagcg ggttcatctc ttcccgtcgc agcatctggc
     5041 acagggcaat aagcggcaag ccgatcagcg tgttcggatc gcggccctct aagcgctcaa
     5101 ataatgcaat gcctaaacct tcgcttttaa aacttcccgc gcagtgcagc ggatgctctt
     5161 tacggacata gtcgtctatt tccgcttcgc ttaaatggcg aaagtgaacg tcaaaaggct
     5221 ccacttcggt ttgtaagtgc ccggaggcgg agttatacag tgccagtccg gtataaaacg
     5281 tcacaatact tccgctggct ttggctaatt gctgacgcgc tttttcttcc gtcagcggtt
     5341 tgccggtgat ttcgccgtcc agaacacaaa tttggtcgga gccaataatc aaatgattcg
     5401 ggaaacgcgc ggcgagcgat tgcgccttag cctgcgccag ccgcagcacc aactgacgcg
     5461 gcgcttcgcc cggcatgggg gtttcatcaa catccggcgc ggcgcattcg aaaggaatcg
     5521 tcagcttttc cagcagcgcg cgacgccagg gagaggtaga cgcaaggatg agacggggca
     5581 tattttttcc ctcagatata gcgtaatgat gagagccatc ttaaactatg ctcttcggtc
     5641 ttcaagcctg tcatactgac tcgtcttgag cgaaaataag tctgtaaccc gcaatgtgtg
     5701 cgaattattg gcaaaaggca accgcaggct gcctttttct ttgactatat gacgttacga
     5761 agttaatatg cgcgccctat gcaaaaggta aaattacccc tgactcttga tccggttcgt
     5821 accgctcaaa aacgccttga ttaccagggt atctataccc ccgatcaggt tgagcgcgtt
     5881 gccgaatctg tagtcagtgt ggacagtgat gtggaatgct ccatgtcgtt cgctatcgat
     5941 aaccagcgtc tcgccgtttt gactggcgat gcggtcgtta cggtgtcgct cgaatgccag
     6001 cgttgcggga aaccgtttac ccatcaggtt cacacaacgt attgttttag ccctgtccgt
     6061 tccgacgagc aggctgaagc actgccggaa gcgtatgagc cgattgaggt aaacgaattc
     6121 ggcgaaatcg atctgctggc gacggttgaa gatgaaatca tcctcgcctt gccggtagtt
     6181 ccggtgcatg attctgaaca ctgtgaagtg tccgaggcgg acatggtctt tggcgaactg
     6241 cctgatgaag cgcaaaagcc aaacccattt gccgtattag ccagcttaaa gcgtaagtaa
     6301 taggtcttcc ccgcggacgc agggataaac cgtaattgag gagtaaggtc catggccgta
     6361 caacagaata aaccaacccg ttccaaacgt ggcatgcgtc gttcccatga cgctctgacc
     6421 gcagtcacca gcctgtctgt agacaaaact tctggtgaaa aacacctgcg tcaccacatc
     6481 actgccgacg gttactaccg cggccgtaag gtcatcgcta agtaatcgcg cgatactcga
     6541 tgccttttgc atcacaggcg tgcctgtggt gtaaaagccg aagagtacaa gcgtgataaa
     6601 gcttagtgag gatttctccg cgtaagcgga gaacaccgaa ccaggcagcg acgatacctt
     6661 gacacgtcta accctggcgt tagatgtcat ggggggcgat tttggtcctt ccgtgacggt
     6721 gcctgcagca ttgcaggcac tgaacgctaa ttcgcagctc actcttcttt tagtcgggaa
     6781 tcccgatatt atcacgccat tacttgccaa agctgacttt gaacaacgtt cgcgtctgca
     6841 gattatccct gcacagtcag ttattgccag tgatgcccgg ccttcgcagg cgatccgcgc
     6901 cagtcgcggg acatccatgc gtgtggcctt ggagcttgtg aaagaaggcc gagccgaagc
     6961 ttgcgttagc gccggtaata ccggggcgct gatggggctg gcgaaattat tgctcaagcc
     7021 tcttgagggg attgagcgtc cggcgttggt gacggtatta ccgcaccagc aaaagggcaa
     7081 aacggtagtg cttgatttgg gggccaacgt cgattgcgac agtaccatgc tggtgcagtt
     7141 tgccgtgatg ggcgccgttt tggcggaaga ggtcgtcggg atcaaaaatc cccgcgtggc
     7201 gctactcaat atcggggaag aagaaaccaa aggcctcgac agtattcgcg aagcctcttt
     7261 aatgttaaaa acagtcccaa ccatcaatta catcggctac cttgaggcga atgagttact
     7321 gacgggaaaa accgatgtac tggtgtgtga cggctttaca ggcaatgtca cgcttaaaac
     7381 gatggagggg gttgtcagaa tgttcctttc actgctgaaa tcacagggcg aggggaaaaa
     7441 acggtcgtgg tggctgctgt tattaaaacg ttggttacaa aaaagcctga cgaggcgatt
     7501 cagtcacctc aaccccgacc agtataatgg cgcctgtctg ttaggattgc gcggcacggt
     7561 gataaaaagt catggtgcgg ccaatcagcg agcatttgca gtcgcgattg aacaggcagt
     7621 gcaggcggtg cagcgacaag ttcctcagcg aattgccgct cgcctggaat ctgtataccc
     7681 agccggattt gaaccgctgg acgatggcaa aggcgtaaac ctgcgggcgc acagataata
     7741 tcgctgtctc cccggcgccg ccagcgtgcc agacgtttac aggtaacggt atataaccga
     7801 aaagtgactg agcgtacatg tatacgaaga ttattggtac tggcagctat ctgcccgaac
     7861 aagtgcggac taacgccgat ttggaaaaaa tggttgagac ctctgacgag tggattgtca
     7921 ctcgtacagg tattcgtgaa cgccatatcg ccgcgccgaa tgaaactgtc gcgacgatgg
     7981 gctttaccgc tgcgaatcgc gcgattgaga tggcggggat cgataaagac caaattggct
     8041 tgattgtggt agcgaccaca tcagcaacgc atgcatttcc aagcgcggca tgtcagattc
     8101 aaagtatgct cggtattaaa ggttgcccgg cgtttgatgt cgcggcagcg tgcgcaggtt
     8161 tcacctacgc gttaagtatc gccgaccagt acgttaaatc cggcgtggtt aaacacgcgc
     8221 tggtggtcgg ttccgatgta ttagcccgca cttgcgatcc tggcgatcgc ggtacgatca
     8281 ttattttcgg cgatggcgca ggcgcggccg tactgagcgc ttctgaagaa ccgggtatta
     8341 tctccactca tcttcatgcc gatggccgtt acggtgaatt actgaccctg ccgaatgccg
     8401 atcgtgtaaa tccggataac ccgatttacc tgacgatggc gggtaatgaa gtctttaaag
     8461 tggcggtcac tgaactggcg catattgtcg atgagacgct ggcggctaat aacctggatc
     8521 gctcagaact cgattggctg gtgccgcatc aggctaacct gcgtatcatt agcgcgacag
     8581 cgaaaaaact cggcatgtcg atggacaatg tcgtcgtcac gctggacagg cacggcaata
     8641 cctccgcggc ttctgtgccg tgcgcgctgg atgaagccgt gcgtgacggg cgaattaaag
     8701 ccggtcagct ggtattgctt gaagccttcg ggggtggatt cacctggggc tccgcgctga
     8761 ttcgtttcta gtataaggat ttaaacatga cgcaatttgc atttgtgttc cccggtcagg
     8821 gttctcagag cgttgggatg ttggccgaga tggcggcaaa ttaccctatc gtagaagaaa
     8881 cgtttgctga agcttctgcg gctctgggat atgatctgtg ggcgctcacc cagcaaggtc
     8941 cagcggaaga actgaataaa acttggcaga cgcagccggc gctattaacc gcttccgtcg
     9001 cgctttggcg cgtttggcag cagcagggcg gtaaaatgcc tgcgttaatg gcaggtcaca
     9061 gcctgggcga atattccgcg ctggtttgcg ctggcgtcat caactttgct gatgccgttc
     9121 gtctggtgga aatgcgcggt aaattcatgc aggaagcggt tccggaaggt actggcggca
     9181 tgtctgcgat catcggtctg gatgatgcct ctattgctaa agcctgtgaa gaatctgccg
     9241 aagggcaggt tgtttcgccg gttaacttta actcgccggg acaggtggtt atcgccgggc
     9301 ataaagaggc ggtagaacgc gcgggcgcag cctgtaaagc cgctggcgcg aaacgcgcgc
     9361 tgccgctgcc ggtgagcgtg ccgtcgcact gcgcgctgat gaaaccaacg gcagataagc
     9421 tggcggttga attagccaaa attaccttta gcgcgccaac ggtgccggta gtaaacaacg
     9481 ttgacgtgaa atgtgaaacc gatgccgccg ctatccgcga tgcgctggtt cgccagttgt
     9541 acaatccggt acagtggacg aagagcgtgg aatttatcgc ggcgcagggc gttgaacatc
     9601 tttatgaagt gggtccaggt aaagtcctca ctggtctgac gaaacgtatt gtcgacaccc
     9661 tgacagcgtc ggcgctgaac gagccggcgg cgctgtctgc ggcacttacg caataaaaga
     9721 ggaaaaccat gagctttgaa ggaaagattg cgctggtgac tggtgcaagc cgtggcatag
     9781 gccgcgcaat tgcagagact ctcgttgccc gcggcgcgaa agttatcggg actgcgacca
     9841 gtgaaaatgg tgcgaagaac attagcgact atttaggtgc taacgggaaa ggtttgatgt
     9901 tgaatgtgac cgatcctgca tctattgaat ctgttctgga aaatattcgc gcagaatttg
     9961 gtgaagtgga tatcctggtt aataatgccg gtatcactcg tgataatctg ttgatgcgaa
    10021 tgaaagatga tgagtggaac gatattatcg aaaccaattt atcatccgtt ttccgcctgt
    10081 caaaagcggt aatgcgcgct atgatgaaaa agcgttgtgg tcgcattatc actattggtt
    10141 ctgtggttgg taccatggga aatgcaggtc aggcaaacta cgctgcggcg aaagcgggcc
    10201 tgatcggttt cagtaaatca ctggcgcgtg aagttgcgtc ccgtggtatt actgtcaatg
    10261 ttgtggctcc gggttttatt gaaacggaca tgacgcgtgc gctgtctgac gatcagcgtg
    10321 cgggtatcct ggcgcaggtg cctgcgggtc gcctcggcgg cgctcaggaa atcgccagtg
    10381 cggttgcatt tttagcctct gacgaagcga gttacatcac tggtgagact ctgcacgtca
    10441 acggcggaat gtacatggtt taatcacgat tgaaaaatat ttgcgttatt agggcgaaag
    10501 gccgcaaaat aacgtaaaat cgtggtaaga cctgccggga tttagttgca aatttttcaa
    10561 cattttatac actacgaaaa ccatcgcgaa agcgagtttt gataggaaat ttaagagtat
    10621 gagcactatc gaagaacgcg ttaagaaaat tatcggcgaa cagctgggcg ttaagcagga
    10681 agaagtaacc aacaatgctt ctttcgttga agacctgggc gcagattctc ttgacaccgt
    10741 tgagctggta atggctctgg aagaagagtt tgatactgag attccggacg aagaagctga
    10801 gaaaatcacc accgttcagg ctgccattga ttacatcaac ggccaccagg cgtaagtgaa
    10861 catctccagg cggtcgttcg accgcctgag ttttatcttt ttgtcccact agaatcattt
    10921 tccctccctg gaggacaacc gtgtctaagc gtcgtgtagt tgtgaccgga cttggcatgt
    10981 tgtctcctgt cggcaatacc gtagagtcta cctggaaagc tctccttgcc ggtcagagtg
    11041 gcatcagcct gatcgaccat ttcgatacta gcgcctatgc aacgaaattt gctggcttag
    11101 taaaggattt taactgtgat gacattatct cgcgcaaaga acagcgcaag atggatgcct
    11161 tcattcaata tggaattgtc gctggcgtac aggccatgca ggattctggc cttgaagtga
    11221 cggaagagaa cgcaagccgt attggcgccg ctatcggctc cggtatcggt ggtctcggtc
    11281 tgatcgaaga aaaccacagt tcgctggtaa aaggcggacc gcgtaagatt agcccgttct
    11341 ttgtcccgtc gacgattgtt aacatggtag caggccatct gactatcatg tatggcctgc
    11401 gtgggccaag catctctatt gcgactgcct gtacttcagg cgtgcataac atcggccatg
    11461 ccgcgcgtat catcgcctat ggtgatgcgg acgcgatggt ggcaggtggc gcagaaaaag
    11521 ccagtacgcc gctgggcgta ggtggttttg gcgcagcgcg cgcgctgtcg acccgcaacg
    11581 ataacccaca ggcggcgagc cgtccgtggg ataaagaacg cgatggtttt gtactgggcg
    11641 acggtgccgg tatgttggtg cttgaagagt acgaacatgc aaaagcacgt agtgcgaaaa
    11701 tctatgctga aatcgtcggc tttggtatga gcagcgatgc ttaccatatg acgtcgccgc
    11761 cggaaaatgg cgcaggcgct gcgctggcga tggttaacgc gttgcgtgat gccgcgattg
    11821 agcctgctca gattggctac gtcaacgcgc acggcacgtc gacgcctgcc ggcgacaaag
    11881 ctgagacgca ggcggttaag tcagtctttg gcgatgctgc aagccgagtg atggtgagct
    11941 cgaccaaatc gatgaccggc catctgttgg gcgccgcagg cgcagtagag tctattttct
    12001 ctattctggc gctacgcgat caggccattc cgccaaccat taatctggat aacccggatg
    12061 aaggttgcga tctggacttc gtgccgcatg aagcgcgcca ggtcagcgat ctggagtacg
    12121 cgctgtgtaa ctcctttggc tttggcggaa ctaacggttc cttgatcttt aaaaagatct
    12181 aagttaagcc agagacagac attaataaaa aggtccgctt gtcgggcctt ttttatcagg
    12241 catatcacct cttgttctgc gttattcatc ctgccacact agcaggcgac ggataaggag
    12301 ccactatgtt tttaattaat ggccatgcgc aggatcaact tgctgtaagc gaccgggcga
    12361 cgcagttcgg cgatggcagt tttacgaccg cacgtattgt tgatggcaac atttgccatc
    12421 tggaagcgca tcttcagcgc ttgcaggttg cctgtgaaaa attacggatc gcttttagcc
    12481 attggtcgac ccttcggcaa gagatgacaa tgttggccac agggcatgat tcaggcgtgt
    12541 tgaaagtgat cattagccgt ggtagcggcg gccggggata cagcgccatg aattgtcagg
    12601 cagctacccg aatcctctcc gtttctgctt atcccgctta ttattctcag tggcgtaagc
    12661 aaggcatcac tcttaccctt agtcccatac cgcttgggcg caatccttat cttgccggat
    12721 taaaacatct gaaccgcctc gaacaggtgt tgattcgctc tcatcttgag cagacggacg
    12781 ccgatgaggc gctggttctt gacagcgagg gatgggttac ggaatgctgt gcggctaatt
    12841 tgttctggcg tacaggcgac attgttttta cgccgcgtct ggatcaggcc ggggtgaacg
    12901 gcattatgcg acaattttgt ttacgccaac tggcgcaatc tcctttccag gttcttgaag
    12961 tacaggcgag agaggaggca gtcaggcagg cggatgagat tatcatctgc aacgcgctaa
    13021 tgccgattat tcccatacgc gcctatcacg ggacgtcgta ttcttcgcga acactgtttc
    13081 aatttttagc cccattttgt gagcatccga attagttatg aaaaaattgt caggcgtttt
    13141 ccttctgctg ttggttgtgc tgggtattgc cacgggcgtg gggatgtgga aagttcgcca
    13201 tctggcgaac agcacgttac ttattaaaaa cgagactatc tttacgctca aggcgggaac
    13261 gggtcggctg gcgcttggtg accagcttta tgatgaaaaa atcattaatc gtccccgggt
    13321 atttcagtgg ctgctgcgcg tggagcctga gttatcgcac tttaaagcgg gaacttaccg
    13381 ttttacgccc gggatgaccg tacgggagat gcttgagttg ctggagagcg gcaaagaagc
    13441 gcaattcccg ttgcggtttg tggaagggat gcgccttagc gattacctga aacagttacg
    13501 agaggcgccg tatattcgcc atacattgcc ggatgatgac tacgccactg tcgctcaggc
    13561 attaaagctt gcgcacccgg aatgggtaga agggtggttc tggcctgata cctggatgta
    13621 taccgccaac accagcgatg tcgctattct caagcgagcg caccaaaaga tggtgaaagc
    13681 tgtcgatact gtctggaaag gtcgggccga ggggctgcct tataaagatc agaaccaact
    13741 ggtgacaatg gcctcgatta ttgaaaaaga gacggctgtc gccagcgaac gcgatcaggt
    13801 ggcctcagtc tttattaatc gcctgagaat cggtatgcgc cttcagaccg atcccaccgt
    13861 gatttacggg atggggacga gttataatgg taacttgtcg cgtgcggatc tggaaaagcc
    13921 gacggcttat aacacgtata ccataaccgg gctgccgcca ggaccgattg catcgcccag
    13981 cgaagcgtca ttgcaggcgg cggcgcatcc ggcgaaaacg ccgtatctct attttgtggc
    14041 cgacggtaaa ggcggtcaca catttaacac caatcttgcc agccataatc ggtcagtgca
    14101 ggagaaagtg cttaaggaaa aaaatgggca gtaattatat cgtcatcgag ggcctggaag
    14161 gcgccggaaa aaccactgcg cgcgacgtgg tggtggagac ccttgagcaa ctgggtattc
    14221 gtaacatgat ttttacccgt gagccgggcg gtacgcagct tgccgaaaaa ctaagaagtc
    14281 tggtgctgga tatccgatcg gtaggcgacg aagtgattac cgataaagcg gaagtgctga
    14341 tgttttatgc cgctcgcgta cagctcgtcg aaacggtaat caaacccgcg ctggcgcaag
    14401 gcgtatgggt gatcggcgat cgccacgatc tctcgaccca ggcgtatcag gggggagggc
    14461 gcggcattga tcaaaccatg ctggcgacac tacgcgatgc cgtgctgggc gattttcgtc
    14521 ctgacctgac gctgtatctg gatgtcacgc cggaagtcgg gctaaaacgc gccagagcgc
    14581 gcggcgattt ggatcgcatt gagcaggaat cttttgattt ctttaaccgg actcgcgcgc
    14641 gctatctgga actggcggcg caagactcgc gtatccgcac cattgacgcg acccagccgc
    14701 tggatgccgt catgcgcgac attcgcgcca cggtgacgaa gtgggtgcag gagcaagcgg
    14761 catgaaatgg tatccatggt tacggcccgc ctatgaaaaa ctggtagaaa gttaccaggc
    14821 gggacgtggg caccatgcgc tactgattca ggccttacct ggcatgggcg acgaggcgct
    14881 gtgctatgcg ctgagccgtt atctgttatg ccagcagcct gagggccaca aaagctgtgg
    14941 gcattgccgt ggctgtcagc ttatgcaggc tggcacgcat ccggactatt acacgctgac
    15001 gccggataaa ggcaaaagca gccttggtgt agatgcggta cgcgaggtca gcgagaaatt
    15061 gtacgagcac tcccgtctgg gtggtgcgaa ggtggtgtgg attgcggatg cggcgctatt
    15121 aaccgacgcc gccgccaatg cgttgctcaa aacgctggaa gagccgccgg agcaaacctg
    15181 gtttttcctt gccagcccgg agcctgctcg tctgttggcg acattacgca gccgttgtcg
    15241 gctgcatcat ctggcgccgc cgtccgaatc gtatgcgatg tcatggctgt cgcgagaagt
    15301 gacggcgtca caagaagcat tgctcacggc gctacgcctg aacgcggggt cgcccggcgc
    15361 cgcgctggcg ctgttgcagt ctgaacgttg ggcgcagcgt gaggcgctgt gtcaggcgtt
    15421 gatggacagt ttacatacgg gcgactggta tgcgttatta acggcgctca atcatgagca
    15481 agccccggcg cgcctgcact ggctggcgac gctgctggta gacgcgctga aacgtcagca
    15541 cggcgcgtcg tacctgacaa acgttgatgc ggacgcggtt gttgccgcgc tggcggggcc
    15601 gctatccccg gcgcgtattc aggcaatcct gaacgatgtt tgccattgtc gtgatcaatt
    15661 acttcatgtg accggattaa atcgcgaact ggtattaacc gatctcattc tccgcatcga
    15721 gcattacctg caaccaggca ccttgttgcc tgttcctcat ctttgagaga gacattatgt
    15781 ttttagtcga ctcacactgc catcttgatg gtctggatta tcaatctttg cataaggacg
    15841 tggacgatgt gctggcgaaa gccgccgcgc gcgatgtgaa gttctgttta gcggtggcga
    15901 cgacgttgcc ggggtatcgc catatgcgcg agctggtggg caagcgcgat aatgtggtct
    15961 tttcctgcgg cgtgcatccg ttaaatcagg atgaagtata tgacgtagaa gaactgcgcc
    16021 tccttgctgc agaagacgat gtggtggcga tgggcgagac cgggcttgat tacttttaca
    16081 cgcctgagac caaaatccgc cagcaggcgt cttttattca tcatatccag attggccgcg
    16141 aattgcataa accggtgatt gtccatactc gcgacgcgcg tgccgatacg ctggctatcc
    16201 tgcgcgaaga aaaagtgacg gattgcggcg gcgtactaca ctgttttaca gaagacagag
    16261 aaacggccgg caaattgctg gatctggggt tttatatctc tttttccggc atcgtaacgt
    16321 tccgtaacgc tgaacagttg cgtgatgcgg cgcgctatgt gccgctggat cggttattag
    16381 tcgagaccga ttctccttat ctggcgccgg tgccgcatcg cggtaaagag aaccagcctg
    16441 cgatggtacg cgacgtcgca gaatatatgg cggtattgaa aggggttgcc gttgaagaac
    16501 tggcgcagat caccaccgat aactttgctc gcctgttcca tattgacgcg tctcgcctgt
    16561 catcaatccg ttaaacgagt ttttttaaag ctcgtaatta ataagcaaag cgcgtaaagt
    16621 tcaccgccac aaaaggggcg gtgagcgagc ttatggaaac attcgaaaac tcattttggc
    16681 agaatgtgat actttttagg ctatctggcg ctgaaacgtg atagccgtca aacaaaatca
    16741 gacgtattta ttttactctg tgtaataaat aaaagggcac ttagatgtcc tgtccacggc
    16801 ggggttctcc cccctcgcca atgcgtgaga acgtagaaaa gcacaaatac tcaggagcac
    16861 tctcaattat gtttaagaat gcatttacta acctgcaaaa ggccggtaaa tcgctgatgc
    16921 tgccggtatc cgtactccct atcgcaggta tcctgctggg tgtcggttcc gctaacttca
    16981 gctggctgcc agccgttgta tcgcacgtta tggcagaagc gggcggatct gtttttgcca
    17041 atatgccgct gattttcgct atcggcgtgg cgttgggctt caccaacaac gacggcgttt
    17101 cggctctggc ggcggtagta gcgtatggca tcatggtgaa aaccatggct gtggttgcgc
    17161 cgctggttct gcatttacct gctgaagaga tcgccgctaa acaccttgct gatacgggtg
    17221 ttctcggggg gattatctcc ggtgcgatcg cagcgtatat gtttaaccgc ttctaccgta
    17281 tcaaactgcc tgagtatctg ggcttctttg cgggcaaacg cttcgtgccg atcatttcgg
    17341 gtctggccgc tatttttacc ggtgtggtgc tgtctttcgt atggccgcca gtcggtacgg
    17401 ctatccaggc gttctcgcag tgggcggctt atcagaaccc ggttgtcgcg tttggcattt
    17461 acggttttat cgagcgttgc ctggtgccgt ttggtctgca tcatatctgg aacgttcctt
    17521 tccagatgca gatcggcgaa tacaccaacg cagcgggtca ggtattccac ggcgacattc
    17581 cgcgctatat ggcgggcgac ccgacggcgg gtatgttgtc tggcggcttc ctgttcaaaa
    17641 tgtacggtct gccggctgcg gccattgcta tctggcactc tgctaaaccg gaaaaccgcg
    17701 caaaagtggg cggtatcatg atttccgccg cgctgacctc gtttttgacg ggtattaccg
    17761 agcctatcga gttctccttc atgttcgtgg cgccgatcct gtacattatt cacgcgattc
    17821 tggcaggtct ggcattcccg atctgtatcc tgctggggat gcgtgacggt acgtcgttct
    17881 cccacggtct gatcgacttt atcgtgctgt ccggtaacag cagcaaattg tggctgttcc
    17941 cgattgttgg cgccggttat gcgattgtgt actacaccgt gttccgcgtg ctgatcaaag
    18001 cgctggatct gaaaacgccg ggccgtgaag actctactga tgacgcaaaa gcgggcgcta
    18061 ccagcgaaat ggcgccggct ttgattgcgg cgtttggcgg taaagagaac atcactaacc
    18121 tggatgcctg tatcacgcgt ctgcgcgtga gcgtagccga tgtagcgaaa gtggatcagg
    18181 ctggcctgaa gaaactgggc gcggcaggcg ttgtcgtcgc gggttccggc gttcaggcta
    18241 ttttcggtac gaaatccgat aacctgaaaa cggaaatgga tgagtacatc cgtaacagct
    18301 aagcagtaat gatgttgggg agtattaagg cagccattcg gctgcctttt ttaatggcgc
    18361 tttacatgac gctctccgac agtctgtcag aactgatagt tggcggtgag gctgacgtta
    18421 cgcggcgcgc cgtaaacaat ggaactatca atattggtgt cgtaggtttt atcgaacagg
    18481 ttgttgatgt ttccctgtac ggagaaattt ttcgtcacct gatagcgggt aaacagatcg
    18541 accagcgcat agctgccctg ttcggcgcgg aaggtgccgt atggcgtcgt ggtatctttg
    18601 taaacccgat tctgccagtt cacgccgccg ccgaccgtca gctccggtat cgccggcaga
    18661 cgatagcggg tgaataactt cacgctggtg cgcgggagat tagggttcac ggcgttacct
    18721 tcattgtcct cggcaacata ccgggtagcc ccgaaagtca tctgccagtt atcggtaatt
    18781 gcgccgttca cttcaaattc gacgcctttg ctcaccgttc cgtcagtaga cttccaggca
    18841 aattccccat tactgccagg gatgggaata gtggttgctt gagcgacatt atcctgctca
    18901 atgcggaaca cggacaacgt agtggtgagg cggctgttca tccagtcgga cttcaggccc
    18961 gcttcatagt tattaccggt aatcggagcc agatattgac ccgctttgtc gcgtttattc
    19021 tgcggctgaa agatagaggt ataactggca taagcggacc agttgtcgtt gatatcataa
    19081 atcagcccgg catacggcgt ggtatggttt ttctccatgc tgtaggtcag tgtatcaaca
    19141 cgccagttgg tataacgagc gccaagaatc agatgcagcg ggtcggccag cgaaatgcac
    19201 gtagcggcat acagcgattt catatgcgtg gtatcgtcct gcgccagatt ttgtggcgcc
    19261 cagtgggttt gggggaaatt accgttaaag gcgccgaagt tgccaatgtc gtccggaaag
    19321 acgttcgccc aggcgctaaa atagcggtta ttctgtttac tataactgcc gccaaacatc
    19381 atattgtgct gacggccaaa cagctcataa gcgccatcag caaagagatc tatggcatct
    19441 actttgcgct tgccgctgtt ccagccagta ccgccgacca cggggtagct tgcgccataa
    19501 ggactcacca gcgtacctgt ctctttatcc actaaagcat cgatatacat cattttactg
    19561 tcgaatttga ccctcagtat gggtcgcatt cagggtcgcc tgccagcttt cggcaaaacg
    19621 ctgcttaagc gtgacgaaga atttatttat ctctttattg ttataagccc agtccggggc
    19681 ggtactacgc gcgcggtcat agctattttt gctgccatcg gtattccagc gcggcagacc
    19741 gccccaggtc gggctgttga catcaatttt ttgatattca taaccggctg aaaggttggt
    19801 agttgcaccc agatcggcat cgataattcc ggaaaagaac gctttctcac tgttatagcg
    19861 gtccagccag gaatcattat tctgataacc cgccacgatg cgcccacgga cattaccgtc
    19921 tgcggtgagc ggactttgca gatccatgac gtaacgctgc ttattccagc taccgtattc
    19981 tgtggagacg ttacctttga actcccgact ggtggcgtgt ttacggatca tattaattga
    20041 ggcagaagga ttgccggttc cggtcatcag cccattcgcg ccgcgaacca cctccacgcg
    20101 ctcatacagc gcggtatccg ttagcgcatc gcccagattc cagcgggact caaaatacgt
    20161 tggaataccg tcaaccatat agttgtcaat ttcaaacccg cgcgagtaat agctgatgcg
    20221 atcggagtca gcctggcttc cgctgatccc cagcgtattg gtcatcacct cgcccagggt
    20281 ttgcaactgc tggtcttcca tacgctgttg gctgacaata ctgaccgact gcgggatatc
    20341 gcgctgagtc atcggcattt tggtgcccgc tgcggtcgtt ttcacgctgt aatcctgttc
    20401 ttcacggttt atggcgtcag cggtcgtcgc gccttcgaca ataacggtat cctcagccgc
    20461 gaaggcggca ggcataaatg ccatcgccat acccatagct aacagcgacg gtgcggcggt
    20521 ggacggaagg tgtttgtccc ggcggtattg aatgaaagac atctgaaaat ccttgcttgt
    20581 tattggggta agttcaggac gtatgacgtt gaaccttttc attctttgct agttaatgcg
    20641 tataaaaatg caaatgagaa atatacgcat ttgtattaaa tgtgtaaaac ggtataacca
    20701 gggaaactag aaatattttt taagcgtaca aaggcgtcat ggcaggggga tatggcggta
    20761 agtccagcat gtagtcattt ttcgcttaat aaatcgtggg ttaaagttga aagagcgtcg
    20821 gtaactcgct catactctat actcgcagta tggctcggcg tagcatgtgc gctgcaaggg
    20881 ctattatgaa aaaggaaaac gtcgtggcag aagaaactat attcagcaaa attattcgtc
    20941 gtgaaatccc ttcggatatc gtttatcagg atgagctggt caccgccttt cgtgatattt
    21001 caccgcaggc gccgacgcat atcttgatta ttcccaatat cctgatccca accgtcaatg
    21061 acgtgacggc ggaacatgaa caggcgttag gtcggatgat caccgtggcg gcgaaaatcg
    21121 ctgaacaaga aggcattgcc gaagatgggt atcgtttaat catgaatacc aaccgtcatg
    21181 ggggccagga ggtttatcat atccatatgc acctactggg cggccgcccg ctaggcccga
    21241 tgctggcgca taaaggcttg taagtatgat caaaggatgc atcgcggttt ctctgggctt
    21301 gctgctgctt accggctgcc ggtcacatcc tgaaattccg gtaagcgacg cgcagtcgct
    21361 ggtgatggag tccgcggttc tggcggcggg tgtcaccgca gagccgcctg aactgacggc
    21421 gtctgatatc cagccatcag cttcttcccg cgtctataac gaaaggcaag agcccataac
    21481 cgttcattat cggttttact ggtatgacgc gcgggggctg gagatgcatc cgctggaggc
    21541 gccgcgtagc gtaaccatac ccgcgcgttc gtcggtaacg ctatttggca gcgccaatta
    21601 tctgggggcg cataaggtca ggctttatct ttatttgtga ggagtgaatt ttgatgacaa
    21661 aaatgcatcg ctacgccgcc attgctgcgc tggcgatatt tctctccggg tgtatggcgc
    21721 aacgtcaacc tgcgccagtt gaagaggtaa aaccagcgcc agaacaaccc gcgcagccgc
    21781 cgcagcctcc tgttgtgccg tctgtgccaa cgattccaca acaaccgggg ccgatcgaac
    21841 atgaagatca aacgggccag ccagcgccta aggtgcgcca ctatgactgg aacggcgcga
    21901 tgcaaccgct ggtcagcaaa atgttgcagg ctgatggcgt gacggccaga agcgtattgc
    21961 ttgtcgacag cgtgaataac cggacgaatg ggtcgttaaa tgcgaacgag gcaacggaaa
    22021 cgttacgtaa tgcgctggcg aacaacggta aatttacgct ggtctccgta cagcaactcg
    22081 cgatggcaaa acagcagtta gggttgtctc cgcaggatag tctgggaacg cgcagtaaag
    22141 ctattggcat tgcgcgcaat gtcggggcgc aatatgtact ttactccagc gcatccggta
    22201 acgttaacgc gcctgcatta cagatgcagt taatgctggt gcaaactggc gagataatct
    22261 ggtcaggtaa aggtgcggtc caacaacaat aatcccttaa cgcgcgacga gatcctgtcg
    22321 cgctattttc cccagtatcg tcccgccgtc gccgcatcgc aggggctaag cggcgggagc
    22381 tgtattattg ctcacgatac tcaccgtatc gtgctgcgcc gtcatcacga ccccgacgct
    22441 ccaccagccc attttttacg tcatcaccgc gccttatccc aattgccggc cagtctggcg
    22501 ccgcgagcgc ttttttatac gccaggctgg atggcggtag aatatctgca tggtgtggta
    22561 aattccgctc tgccagatgc cgacgaactg gcggccttac tgtatcattt gcatcaacag
    22621 ccgcgttttg gctggcgtat cgcgctatcg ccactattgg cgcagtactg gtcgtgttgc
    22681 gatccggcaa ggcgtacgcc gttttggttg cggcggctca aacagttgca aaaaaacggt
    22741 gaacctcgcc cgctgcggct cgcgcctttg catatggatg tccatggcga caatatagta
    22801 ttaacgtccg ccgggttgag actgattgac tgggagtatg ccggcgacgg cgatattgcg
    22861 ttggagctgg cggcagtatg ggttgaggat gaacgccagc accgacaact ggcagacgct
    22921 tatgccgcgc gcgcgcgaat cgacgcccgg cagctatggc gacagatacg attatggcac
    22981 ccctgggtca ttatgctaaa agcagggtgg ttcgaatacc gctggcgaca aaccggcgag
    23041 caacaattta tcaggctggc cgatgaaacc tggcgccagc tacgtatgaa aggataagga
    23101 gagcagtgtg ggcccagtaa tgttgaatgt cgaaggatgt gagctggatg cggaggagcg
    23161 cgagatactg gcgcatccgc tggttggcgg gcttattctg ttcacgcgta attaccatga
    23221 cccggaacag ctgcgcgaat tagtgcgcca gattcgggcg gcatcgcgta accatctggt
    23281 ggtggccgtc gatcaggaag gcgggcgcgt acagcgtttc cgtgaagggt ttacccgcct
    23341 gcccgcggcg caatcttttt ttgcgctgca tgggctggaa gagggggggc gactggcgca
    23401 ggaggcaggg tggctgatgg ccagcgaaat gatcgcgatg gatattgata tcagttttgc
    23461 gccagtgctg gacgttgggc atatcagcgc ggcaattggc gagcgttctt atcatgccga
    23521 tcccgcaaaa gcgttggcaa tggcaacacg ctttattgac ggcatgcatg acgccgggat
    23581 gaaaacgacc ggtaagcatt tccccggcca cggcgcggtc acggcggact cccacaaaga
    23641 gacgccgtgc gatccacgtc ctgaaacgga catccgtggc aaagatatgt cggtgttccg
    23701 cgcgctgatt agtgagaata aactggatgc gattatgcct gcccacgtga tctaccgcgc
    23761 tatcgatccg cgtccggcaa gcggttcgcc gtactggctg aaaacggtgc tgcgtcagga
    23821 gctaggcttt gacggcgtca ttttctccga cgatctgtct atggagggcg cggcgattat
    23881 gggcagctat gctgagcgcg ctcaggcgtc gctggatgcg ggttgcgata tgattctggt
    23941 ctgcaataat cgtaaaggcg cagtcagcgt gctggataat ctgtcgccga tcaaagcaga
    24001 acgtgttaca cgtttgtatc ataaaggttc attttcacgc cgggagctca tggactcagc
    24061 acgctggaaa acagccagcg cccagctcaa ccagttacat gaacgctggc aggaagaaaa
    24121 agcaggtcat taactcgagt tttcgtgagg gtgccagatg attatttatt tacacggttt
    24181 tgattcaaat agtccgggta accatgaaaa agtgttgcaa ttacaattta tcgacccgga
    24241 tgttcggctg gtaagctaca gtacgcggca tcctaagcac gatatgcagc atctgctgaa
    24301 agaagtggac aaaatgttgc agttgaatgt ggacgagcgc cctttaatct gtggcgtagg
    24361 gctgggcggt tactgggcgg agcggattgg ctttttgtgc gatatccgtc aggtggtttt
    24421 taacccgaac ctgttcccct atgaaaacat ggaggggaaa atcgatcgcc cggaagaata
    24481 tgcggacatc gctacaaagt gcgtgaccaa ctttcgcgaa aaaaatcgcg atcgttgtct
    24541 ggtgatcctc tcgcgtcatg acgaagcgct ggacagccaa cgctcagcgc aagcgcttca
    24601 cccgttttat gaaattgtgt gggatgagga acagactcac aaattcaaaa atatttcgcc
    24661 gcacttgcaa cgtatcaaag cgtttaaaac gctggggtaa cgccatccgg caatatggcg
    24721 ttatcagtga ccggataacc agccttgcgg ctggtttttt tatgctcaat tctcgcaaac
    24781 tgtctatctt ttcagcatga aaacttgatg cacatcaatt ttggtatgac caatgcaccg
    24841 ttcatgctat tctcatatca gaagcttatt ctcattaacg taacttgttg ttaattaaag
    24901 gctatactaa taacttttaa ttaacaattg gttaataaat ttaagggggt cacgttgact
    24961 acaccattaa aaaagatcgt gattgtcggc ggcggcgctg gcgggctgga aatggcgacg
    25021 cagttaggcc ataaactggg gcgcaagaaa aaagcgaaaa tcacgctggt agacagaaat
    25081 cacagccatc tgtggaaacc attgctgcac gaagtggcga ctggctctct ggacgaaggc
    25141 gtggatgcgc tgagctatct ggctcatgcg cgtaatcatg gtttccagtt ccagctgggg
    25201 tcggtgatgg atatcgatcg cgaagcgaag accatcacca ttgccgagtt gcgtgatgaa
    25261 aagggcgaac tgctggtgcc ggagcgcaaa atcgcgtatg acacgctggt gatggcgctg
    25321 ggcagcacct ctaatgattt caacacgccg ggcgtgaaag agcactgtat cttcctcgat
    25381 aacccgcatc aggcgcgccg ttttcaccag gagatgctga acctgttcct caagtattcg
    25441 gctaacctgg gcgcgaacgg taaggtcaat atcgccatcg ttggcggcgg tgcgacgggg
    25501 gttgagctgt cggctgaact gcataatgcg gtaaaacagc tgcatagcta tggttataag
    25561 gggctgacca acgacgcgtt gaacgtgacg ttggttgagg ctggcgagcg tattctgcct
    25621 gcgttgccgc cgcgtatctc cagcgccgcg cataatgaac tgaccaaact gggcgttcgc
    25681 gtactgacgc aaactatggt caccagcgcc gacgaaggcg gtctgcatac gaaagaaggt
    25741 gaatatattc aggccgatct gatggtgtgg gcggcgggta tcaaagcgcc agattttatg
    25801 aaagaaattg gtggtctgga aacgaaccgc attaaccaac tggtggtgga accgacgctg
    25861 caaaccacgc gtgatcctga tatttatgcg attggcgact gcgcttcctg cgcacgtccg
    25921 gagggaggtt ttgtgccgcc tcgcgctcag gcggcgcatc agatggctac ctgcgcgatg
    25981 aataacattc tggcgcagat gaatggcaag ccgctgaaag cttaccagta taaagatcat
    26041 ggatcgctgg tctctctgtc caacttctct accgtgggta gtctgatggg gaacctgacc
    26101 cgcggttcaa tgatgattga aggacgtatc gcccgcttcg tgtatatctc gctataccgt
    26161 atgcaccaga tagcgctgca tggatacttt aaaaccggcc tgatgatgct ggtgggcagt
    26221 attaaccgcg tcattcgtcc gcgcctgaaa ctgcattaat ttttctgcgc ctcaccggct
    26281 gctcgccggt gagcgcttct ccatcacttg cttcggagtt gtccgaatcc ttcagcttta
    26341 ccgcctcatc ccgcattttt catcctcatt ccgattggct ttgttcgcat actggttgca
    26401 aaattgttac caatagcaac gaaggaggaa ctcccgtgaa taaatcaatg ttggcgggta
    26461 tagggattgg cgtagcggct gcgctgggtg tggcggcagt ggccagtctc aacgtatttg
    26521 atcgtggtcc gcagtatgcg caggtgatat cggctaaacc gattaaagag acggtaaaaa
    26581 cgccgcgtca ggagtgccgt aatgtcacgg tcacgcatcg tagaccggtt caggacgaaa
    26641 accgtattgc cggctcggtg cttggcgcag tagcaggcgg cgtgattgga catcaatttg
    26701 gcggcggtcg tggtaaagat gtggcgacgg tcgtcggggc gctgggcggc ggttatgctg
    26761 gcaatcaaat ccagggatca atgcaggaga gtgataccta cactaccacg cagcaacgct
    26821 gtaagacggt gtatgacaaa tctgaaaaga tgcttggcta cgacgtgacc tacaaaattg
    26881 gcgatcagca gggcaaaatc cgcatggata aagaccccgg aacgcaaatt cccctcgacg
    26941 gcaatggtca actggttctg aataacaaag cataaaaaag ctgtactctg caagttagcc
    27001 cctcattcgc tcaggctgag gggctttttt tatccgaagc cgcgtcgttc aggacttgag
    27061 cagttcaggc cagatgcgca gagtcgtacg cgtaatttgc atcagttgtt cgaaggtggc
    27121 accttcacgg gcgctgatcg acattccctg taaaatacag tttatatatt ccgcgagcgc
    27181 ctgcgggtta cagtgcgccg gaatttcacc gcgctcctga tgttggcgca gaaactggat
    27241 gagcgtctgt tcctgcatgg cgtggcgtga ttttaccgtg cgggcgatat cgcgcgagga
    27301 ggcggccagg gtggcggacg tattaatcat aaagcagcca gccggcgtgt ctgtactggt
    27361 aaagcaggcg gcaatttctg tgaagtaatc ttccagcgcc gattctacgc ttttctcttc
    27421 acaaaagagc tgggcttcgt gttttgaggc aaagcgagtg atgtagcgat ccaggacagc
    27481 gcgaaataat ccttctttgt tagtgaattc cgcatagaga gtaggcgctt tcgccccggt
    27541 agcctctacg agatcggcaa gcgaagttgc ttcatagccg tgctgccaga agagagtcat
    27601 ggccttatca agcgcggctt ccctgtcgaa cacttttggt cggccacggc ttttcttcgc
    27661 gcaactcgtg gtatccgttg tcatgatgcc gttgtacctg tttaaagagc ggtctctcta
    27721 ttataaaaac aaaccacttc tggctccaga gtattcatta gaaaaataaa tcaattctat
    27781 tcacatgaaa aataacatct ttataaatta tataacgatc attataaaaa gaggttgacg
    27841 tgtgatgtag atcacatcta tgattaattt atcgatcgtt aagttaatgc ttgcgacacc
    27901 cattcatctg ctaaaggtca tcactatgaa aaacgtaaaa aacctcatcg ctgctgcggt
    27961 actgagttcg ctctcattcg ccagcttcgc cgccgttgaa gttcaggcaa cgccagaagg
    28021 tcaacagaag ttcggcacca tttccgcgaa tggcggcacg aatctgggct cgctggaaga
    28081 tcagctggcg caaaaagcgc aggaaatggg ggcgaagtct ttccgtatta cctctgttac
    28141 cggcccgaat accctccacg gtacggcggt aatctataag taagcattaa ccctcattaa
    28201 tgccgctgcg attgccacaa taaaaagaga aagcctcgcg atgcatcgcg aggctttttt
    28261 gtcagtcagc tattcacgct tacagcgact gatgaacttc caccagtcgc acgccgcctg
    28321 gctccaccga ggctttaatc ggcgtattga taatattcac tttggttccc ggcgtgactt
    28381 gacggaacaa tgtctctata tcaccgtcgc gcagacggat acagccggaa ctgacgcgca
    28441 taccaatgcc aaaaccggca ttcgtgccat gtaacagata gacgccgccg taggccgcta
    28501 aacgaatcgc gtgatgcccc attgggttat cgggaccggc aggcaccacg gcggggagat
    28561 cgatgccttg cgctttataa cgggcgcgaa tattggtggt cggcgtccag gttggattgg
    28621 cgcgtttatc cgaaatggtc gtcaccatcg ttggcgtcag ggtatcgccg cccagttggc
    28681 caatgccgat agggtagacc gtgaccgtat ttttccccgg ttgataatag taaagccgta
    28741 attcagcgag gttaatgacg ataccttcac gtggcgcgtc cggtagcagc gtttgcagcg
    28801 gaatcgtcag cacgctgcct gcgcgtggca cgtaaggatc aatgccgggg ttggcctgta
    28861 acagggctaa aaagcccacg ttatattttt tggcgatcgc ctccagcgag ccgccgtcgt
    28921 cttcaacgac atggaattta ttttctccca ccagtcgact gccggggggc ggaagaggcc
    28981 acgtattcgc ctgcgcggga agggcaagca tgatggtcgc ggtaagcgca agcaacgccc
    29041 accagcgaga gagtcgcgta ttgttgaaca ttataataag cccatgatta ttatgtggtt
    29101 atttttataa aagaggaaat aagaattatg gcggttggct gtgtctggaa ctgcagggaa
    29161 gtgcaaagaa tttgtaaaga ttaggccggg cgcagagtaa tgacgcccgg cctgacgctt
    29221 atgcaatagc gttttcttcc agttgctgca tgaactggcg tacccagtct atacgcgttt
    29281 tacgttcgct taaatcctga ataaacttga ggcgcgtcgg gccatccaga cggaaatgct
    29341 gcggctgttt ttgcagtaac ccgataagcc aggcggggtc aacgtggttt ttctcggcga
    29401 actcaatcgt tccacctttc tcgttaccct ccagttttcg gatgccgagc ttttgcgcct
    29461 gttggcgcag gcgggcgata tccagcagat tacgcgccgg atcgggcagc aggccgaagc
    29521 ggtcgatcaa ttccactttg atctcttcca gctcgttttc gttcttcgcg ctggcaatgc
    29581 gtttatagaa tgacagccgg gtattaacat ccggaataaa atcatccggc agtaacgacg
    29641 gcattcgcag ctcgacttcc gtttgctgac tggtgagatc ttccagcgag ggttcgcggc
    29701 ctgctttcag cgcatcaacg gcgttttcca gcaattccat gtagagtgag aagccaatgg
    29761 tttccattga gccgctttgc tcttcgccaa gcagctcgcc cgcgccgcgg atctccagat
    29821 cgtgggtcgc cagcgcaaac ccggcgccta aatcctccag cgacgcaatc gcctccagcc
    29881 gtttttgcgc atcggcggtc atggccttag gatgtggcgt caacagccag gcgtaggcct
    29941 ggtggtgcga gcgccctacg cggccacgca gctggtgcaa ctgcgcgagg ccgaaatgat
    30001 ccgcgcgttc aatgatgatc gtgttagcgg tgggaatgtc gatccccgtt tcgataatgg
    30061 tagtacacac cagcacgtta aaacgttgat ggtggaaatc gttcatgacc cgttccagct
    30121 cacgttcgcg catctgcccg tggcctatag cgattcgcgc ttccggcacc agttccgcca
    30181 gccgctctgc ggctttctga atattttcga cgtcattgta caaatagtaa acctgaccgc
    30241 cgcgcaggat ttcacgcaga atcgcttccc ttaccaccag gctatcatac tcgcggacaa
    30301 aggtttttac cgccagacga cgggcagggg gagtggcgat aatggagaga tcgcgcatac
    30361 cgctcatcgc catattcagc gtccgcggga tcggcgtcgc cgtgagcgtc agaatatcga
    30421 catcggcgcg catcgcctta attcgctctt tgtggcgcac gccgaaacgg tgctcttcat
    30481 cgacaatcag caggccgagg tcgcgtagct tcacatcgct ttgtagcagt ttatgcgtac
    30541 cgatcagaat atcgatctta ccttcggcgg cttccgccag gatttgcgtc tgctctttgg
    30601 cgctgcgaaa gcgggacagc atctcaatgc gtaccggcca gttggcgaaa cggtcgcgga
    30661 agttgtcata gtgttgctgc gccagcagcg tagtcggcac cagtaccgcc acctgtttat
    30721 ggttttccac cgccaggaac gcggcgcgca tcgccacttc ggttttgccg aagccgacgt
    30781 cgccgcacac cagcctgtcc atcgccagcg gttggcacat atcgctcaat acggcgttaa
    30841 tcgcctgtgc ctgatcgggc gtcgtttcaa acgggaagct gtcgcagaat aactgatact
    30901 gctcacgatc atgcttaaag gcaaaaccct cttttgccgc tcgttgcgca taaatatcca
    30961 acagttccgc tgcgacatcg cgcacttttt ccgccgcttt ctgccgggcg cgcgaccagg
    31021 cgtcgccgcc cagtttatgc agcggcgcac tttcttccgc gccgccggca tagcggctaa
    31081 tcagatgcaa tgaggagacc ggcacataca gtttggcgtc attggcgtaa gtgagcatca
    31141 gatattcacc cttgatgccg ccagcctcca gagtggtcat gccggcatag cgtccgacgc
    31201 cgtgctccag atgcactacc ggttgaccga cgtggagctc cgccaggtta cgaatcaacg
    31261 tatccgggtt gatcgtgcgg cgggaatcca ggcggcgacg cgccacccgc tcacccaaaa
    31321 gatcgctttc acaaatcagc gccagattgc gttgggtgtc gataaagcca tgttctgcgg
    31381 cgccaatcat cagatagcgt cccgcatcct gcgcctcgtc caggcgtaat attcgcttcg
    31441 gcgcgatttt tatgcgagcc aggagctctc ccagagcttc gcggcgtcct tcgctttcca
    31501 ccgaaaaaat caccggaccg ctgaaagatt cgaggaactt acgcagcgcg tccagcggcg
    31561 ctttctgctg tgcctggata gccaaatccg gtaatttctg gaaaccgaga ttggtattgg
    31621 cggctttttc cggcagatgg tcggttttaa gctggaggcg aggccagcgt ttaagctcgg
    31681 aaaagagccc atccacccgt agccagaggg cttccggcgg caaaagcggg cgcataggat
    31741 cgacgccacg attttcaaaa cgcgccagcg tatcggcctg aaagcgttcg gcgctggttt
    31801 ccagcgagcc ggtattcacc accagagtat tggcggggaa atagctaaat aatggcggta
    31861 acggttcgct gaaaaagagc ggctgccagt attcgatccc ggcgggcaga gtgcctttgc
    31921 taacctgctg atagatgtgc tcggcgtcgc gttttacctc aaaggtatcg cgccactggc
    31981 tacggaaaag ctcaatagcg gctttgtcgg taggaaattc gtgcgcgggc aacaaattga
    32041 tggcctcaac ctcctccagc gtacgctggg tatccgcgtc aaacagacgc aggctgtcaa
    32101 tttcatcatc aaaaaagtcg aggcgataag gctgttcgct gcccatcgga aagagatcca
    32161 acagcgcgcc gcgcgtcgcg tattcgccat gctccatcac ctgatcgaca tgccgataac
    32221 cggcgctgtc aagctgcgcg cgcagagcgt cgcgggacag ccgctggcct tttttcatca
    32281 ccagcgcatg accatgcaga tagctatgct gacaaacgcg ctgcatcagg gtgtttaccg
    32341 gtacaatcaa gacgccgcgc tgcattgacg gcaactggta gagcgtggac aggcgcgaag
    32401 agataatttc ctgatgcggg gagaagctgt catacggtag cgtttcccag tccgccaggt
    32461 tcatgaccat ctgatcggta aactggcgga tttcatcatg caatcgcaga gcattttgca
    32521 tgtcaggcgc tatgagtacc accggaccgg catggcgttc agctatctcc gccaccagcg
    32581 tagcgcaggc ggcaccggta agttcgccca actggcgctg atcgcccgct tttgtcggca
    32641 gcgtgtaacg ttgtttttca ggcataacgg ttgtcagtat ctctttttgt tttacgccgc
    32701 actctacgcg tcacccttca ggctgcttca tggttggctg cgcgccagga cagcatgaag
    32761 gactcaggta ttcaggggca tatgactgat aagcaatgtt ctttattatc cgcgatcgtt
    32821 gtttattagc aaattgaatc cgccggataa cacgccgaac aggtaaagta tgaacatgta
    32881 agtgacttga tttgtcggcc tttttcagaa taacgctgac gaactcttac ggttcagaca
    32941 tttacgcatt ccgctttcgc ttatatactc gggactttgc taacagcaac cagacggatt
    33001 acatgtatca acctgtcgct ttattcatcg gcctgcgtta catgcgcggg cgtgcagcag
    33061 atcgcttcgg tcgcttcgtt tcctggcttt ccactatcgg cattaccctg ggggtgatgg
    33121 cgctggtcac ggtattgtcg gtgatgaacg gttttgagcg cgaactgcaa aataacattc
    33181 ttggtttgat gcctcaggcc atcctctctg ctgaacatgg ttctcttaac ccgaatcaga
    33241 tgccggaaaa agcggtgaat ctgcaaggcg ttaaccgtat tgcgccgctg acgacgggcg
    33301 atgtcgtact gcaaagcgcg cgtagcgttg cggttggcgt gatgttgggt atcgatccgg
    33361 cgcaaaaaga tccgttaacg ccgtatctgg tcaatgtgaa gcaaagcgaa ttacagccgg
    33421 gtaagtataa tgtcatcctc ggcgagcagc tcgccggaca gttaggggtc aaccgcggcg
    33481 atcagattcg gctaatggtg ccatctgcca gccagtttac gccaatggga cgcctgccca
    33541 gccagcgtct gtttacggtg attggcacat ttgccgccaa tagcgaggtc gatggctatg
    33601 aaatgctggt caatattcag gacgcgtcgc gtttaatgcg ctatccggca ggcaatatta
    33661 ccggctggcg tctgtggctg gatgaaccgc tgcaagtcga tactctcagc caacagacgc
    33721 tgccgcaagg cacgaagtgg caggactggc gcgaacgtaa aggcgagttg ttccaggctg
    33781 tgcgcatgga aaagaacatg atgggattgt tgctgagcct catcgtggcg gtcgcggctt
    33841 ttaacattat tacttcgttg ggtctgatgg tcatggagaa gcagggcgaa gtggcgattt
    33901 tacaaactca agggctgacg ccgcgacaaa ttatgatggt ctttatggtg cagggcgcca
    33961 gcgccgggat tatcggcgcg ctgttgggcg ccgcgctggg cgcattgctt gccagccaac
    34021 tgaataacct gatgccgatc atcggcgcgt ttctggatgg cgctgcgttg cccgtggcga
    34081 tagagccgtt acaggtgatc gttatcgcgc tggtggcaat ggccatcgcg ctgctttcta
    34141 cgctttatcc ttcctggcgc gctgccgcca ctcaacccgc tgaggcttta cgttatgaat
    34201 aagatcctgt tgcaatgcga caacctgtgc aaacgctatc aggaaggcac cgtacaaacc
    34261 gacgtgttgc acgatgtcag cttcagtatc ggcgaaggcg aaatgatggc gatcgtcggc
    34321 agttccggtt cgggtaaaag tacgttgctg catctgttag gcgggctgga tacgcctacc
    34381 tctggcgatg tgatttttag cggccagccg atgagcaaac tctcttctgc ggcaaaagcg
    34441 gaattacgta accagaaact ggggtttatc tatcagtttc atcatctcct gccggatttt
    34501 acggcgctgg aaaacgtggc gatgccatta ttgattggca aaaagaaacc ggcggagatt
    34561 gacgctcggg cgcgagaaat gttgcatgct gtagggctgg agcatcgcgc aacccatcga
    34621 ccttcggaac tttccggcgg tgagcgccag cgtgtcgcga tagcgcgcgc gttggtgaat
    34681 aacccgcgtc tggtactggc ggatgagccg accggtaatc tggatgcgcg taatgccgac
    34741 agtatttttg agcttctggg cgagttaaat cgtctgcagg gaaccgcgtt tctggtggtg
    34801 actcacgatt tgcaactggc gaaacgtatg agccgccagc ttgagatgcg cgatggccgc
    34861 ctgacagcgg aactgagcct gatgggggct gagtaatggc gtcgccttta tcattgttaa
    34921 ttggcttgcg tttcagccgt ggacggcggc gcggcggtat ggtttcgctc atttccgtca
    34981 tttctaccat cggtatcgcg ctgggcgtgg cggtgttgat tgtcggttta agcgcgatga
    35041 acggtttcga acgcgagttg aataaccgta ttctggcggt ggttccacac ggggagattg
    35101 aagcggtcaa tcagccgtgg accaactggc gtgaagcgct ggcaaaagtg cagaaggtgc
    35161 cgggcattgc cgccgccgcg ccgtatatca attttaccgg cctggtagag agcggggcga
    35221 atttgcgcgc cattcaggtt aaaggcgtcg atcctaagca agagcagcag cttagcgcgt
    35281 taccgtcatt tgtgcaaaat cacgcctggg atcatttcaa agcgggcgag cagcagatca
    35341 ttatcggtaa aggcgtcgcc gatgcgctga acgtgaaaca gggcgactgg gtgtccatca
    35401 tgatccccaa tgcgaatgcc gaccataagc tgctccagcc caaacgcgtg cgtttgcatg
    35461 tcatcgggat tctgcaactg agcggccagc tcgatcacag cttcgccatg atcccgcttg
    35521 aggatgcgca gcagtatctg gatatggggt ccagcgtttc cggtatcgcg cttaaagtcc
    35581 acgacgtgtt taatgcgaac aaactggtgc gtgatgcggg tgaagtgact aacagctatg
    35641 tctacattaa gagctggatc ggcacctacg gctatatgta tcgcgatatc cagatgattc
    35701 gcgccattat gtatctggcg atgattctgg tgatcggcgt ggcctgtttt aatatcgttt
    35761 ccaccttagt gatggcggta aaagacaaaa gcggcgacat tgcggtatta agaacgctgg
    35821 gggcgaaaga tggtttgatt cgtgccattt tcgtctggta cggactactg gcgggcttgc
    35881 tgggcagctt gattggcgtg gcgatcggcg ttgtcgtttc gcttcagctt accgccatta
    35941 ttaatgggat tgaaaaggag atcgggcatc agtttttgtc cggcgatatc tattttatcg
    36001 acttcctgcc atccgaatta cattggctgg acgttgttta cgtactggtc acggcgttgt
    36061 tgttaagctt actggcgagc tggtatccgg cgcggcgggc gagcaacatt gaccctgcgc
    36121 gagtattgag cggccagtaa tcgcggaata taaaaacaag gagcggcgat gtattacggg
    36181 tttgacattg gcggaacaaa gattgcgtta ggcgtatttg actcaacgcg gcggctgcag
    36241 tgggaaaaac gggttcccac gccccatacc agctatagcg cctttttaga cgccgtgtgc
    36301 gaactggtcg cggaagccga ccagcgattt ggcgtaaaag ggtcggtagg gattggcata
    36361 cccggtatgc cggaaactga agacggcacg ctgtacgccg cgaatgtccc ggcagccagc
    36421 ggtaagccgt tgcgcgccga tctcagcgcc cgactggatc gcgatgtgcg tctggacaat
    36481 gacgctaact gttttgcctt gtccgaagcc tgggatgatg aattcacgca atatcctttg
    36541 gttatggggc ttatcctcgg caccggcggc ggcggcctgg tgctaaacgg gaagccgatt
    36601 accggtcaga gctatatcac cggcgagttt ggccatatgc gtttgccggt tgacgcgcta
    36661 acgttgatgg ggtttgattt tcctctccgc cgttgtggat gcggccagat gggctgcatt
    36721 gagaattatc tgtccgggcg cgggtttgcg tggctatatc aacattatta tgatcaatcg
    36781 ctgcaggcgc cggagattat cgcgttgtgg gagcagggtg atgagcaggc gcacgcgcat
    36841 gttgagcgct atctggattt actggcggtt tgtctgggga atatactgac gattgtcgat
    36901 cccgatttat tggtgatcgg cggcggacta tcgaacttta cggcaataac aacgcaactg
    36961 gcggaaagac tgccgcgcca tctcctccct gttgcccgcg cgccgcgcat tgagcgtgcg
    37021 cggcatgggg atgcaggtgg gatgcgcggt gctgcttttt tacatcttac cgactaatca
    37081 aaaaaagagg ttgttatgca gtcgcgtcgg tttcatcgat taagccgctt tcgtaaaaat
    37141 aaacgtctgt tgcgtgaacg tctgcgccag cggatctttt tcagagacag agtggtgccg
    37201 gaaatgatgg aaaacccaag agtattagtc cttacaggtg caggaatttc tgcagagtct
    37261 ggtattcgta cgtttcgcgc ggcggatggc ctttgggaag agcatcgggt tgaagacgtg
    37321 gcaacgccgg aaggattcgc ccgtaatccg gggctggtgc agacatttta taatgcccgc
    37381 cgtcagcagc ttcaacagcc ggaaatacaa cccaatgcgg cgcatctggc gttagcgaag
    37441 cttgaagaag cgcttggcga tcgctttttg ctggtgacgc aaaacatcga caatttgcat
    37501 gaacgcgcgg gcaaccgcaa catcattcat atgcatggcg agctgttgaa ggtgcgctgt
    37561 tcgcaaagcg gccagattct ggaatggaac ggcgatgtga tgccggaaga taaatgtcac
    37621 tgctgccagt tcccggcgcc gctacgtccg cacgtggtgt ggtttggcga gatgccgctt
    37681 ggcatggatg aaatttatat ggcgctgtcg atggcggata tttttatcgc cattggcaca
    37741 tccggtcatg tctatccggc tgcgggtttt gtgcatgaag caaaactgca cggcgcacat
    37801 acggtggaac tgaatcttga gccaagccag gtcggcagcg agtttgaaga gaagcactac
    37861 ggcccggcaa gccaggttgt gccggaattt gttgataaat tcctgaaagg gctgtagtgc
    37921 cgtttgcccg gtaacgcctt atccggccta catttcacgt tacgttcatc tgtaggcccg
    37981 acaggcgctt tggctgaatt agcgtcctgc ttttagcttc tgataatact cttcataaat
    38041 ggcgctggcg tcgccgacat cgttttgcca ctcgcctttg ctgatggttt gcgcatccgg
    38101 atagagcgac ttatcattgg cgacctccgg gcttaacagc ttacgcgccg ccaggttggg
    38161 ggtagggtag ccgatggttt ctgccacctc tttcgcgacg tcaggacgca gcaggaagtt
    38221 gattagcttc agcgcgccct ctttattttt cgcgtttgcc ggaatagcca ggctatccat
    38281 ccagaaaata ccgccttctt tcggccagac gacctccagc ggcgtgccag cctgacgagc
    38341 aacgaaggcc gaaccgttcc acaccatccc cagattgact tccccttcca tatacggatt
    38401 cgccggatta tcggagttga aggccgctac gttcggcatc agttttttca actcttcata
    38461 tgccgcttcg atctctttag gatcggtagt gttaccggaa taacctagct tgcgcagcgc
    38521 catctggaag acttctcgcg catcgtcggt taaaagcagg ctgtttttat attccggttt
    38581 ccacaaatca gcccagctgg taatggtttt tggatcgata gcatcgctgt tcacgccaat
    38641 cgccgttgcg ccccagatat acggaacaga ataatcgttg ttggggtcaa acggtttgtt
    38701 gagcatttcc ggatcgaggt tgtggaaatt ggttaatttc gacttatcga tcttctggat
    38761 catgccttct ttgcgcattt tgtcgacata gtatgtagaa ggaacaacca ggtcatacgc
    38821 gccatcttta taggttttga gtttggcata catggtttcg ttcgactcgt aggtcgaata
    38881 aatcacctta atgcctgtct ctttagtgaa ctgttccagc aggcccggcg gtacatactc
    38941 agtccagtta tagaaataga gcgtgtcgtt gtcggaggca tgagcggcac tcatacccag
    39001 cgccagggcg cctgccgcga gcaggtggcg tgaccatttt ttcatttaac gtcccctgaa
    39061 ttacgggcct tatcggccct tggttttatc acgagcaata agctggctgg caatgaccat
    39121 taccagagac agcaccaata aaacggtcgc cagcgcgttc acttctggtg aaacgccgac
    39181 ttttaccatg gaataaatct ttaagggtaa aatttcatag cccggcccgg tgacaaacga
    39241 cgagactact acatcgtcca tcgacaacgt aaagctcagc aaccagcccg ccgccaccgc
    39301 cggcatcgcc agcggcagaa tgattttgcg taaaatcgtt acctcactgg cccccaggtc
    39361 ttttgcggct tccagcattc tgacatcaaa gcctttcagg cgcgaataga ccgtgacgac
    39421 cacaaacggc aggctaaagg tgatgtgcga gaacagcaac gaccaaaagc ccagttgaat
    39481 gccgagtaac ataaacagca ccagcaggga gatcgccatc acgatatccg gcgacatcat
    39541 tactacaaac agcatcccgc tgacgaatgg cttcccgcga aagcggtagc gataaagcgc
    39601 taccgcggtt aacgagccaa tcaacgtggc gaaggtcgct gagaaaatcg ccatcgtcag
    39661 tgaatgttga gcggcctgta acagactgtc gttattgacc agtagttcgt accatttagt
    39721 ggtaaagccc tgccagttaa tgccgaaccg cgaactgttg aaggagttca cgatcagaat
    39781 aatgatggga atatacagat acgcatagat ggcagtcatg aaaccgccac ggagcagccg
    39841 accgatcatt caagttccac cttcttattc agaggatggg gtgcttttag agtattgaaa
    39901 atgatcaatt ttttctcttc tccaaaatct ctccaaaacg tctcgcggtt atcagcagcc
    39961 aggaagaagc aagctgccgc ttgaagccgc gaattttaca acaaattgcc agacgagcgg
    40021 gaaaaaaagg ccatttaaat gactattctc atccgatccg gtcatatgcg gcattattgc
    40081 gccaggcaag aggttactct gtaggcaaac atgaagtacg tgagtaaacc ctgaacgtga
    40141 cgtctgagaa agcgtcgtct gattttataa aaaacaacat aaatagccgc tttgttgttc
    40201 tgagcgaacg tgtagcgtgg ttaactgttc ttccgccatt ttttgtatag actggggggc
    40261 tattctaaaa atggcgtgaa aaacctgatc agagatggct tcgactatct cagctaacat
    40321 gcttaggctg gcgctgggat ccgttacaag gaacgcctga aacgtcttat ccgccagtaa
    40381 aacctcttct accatttttt caataggtat gtgggtatgt ggtggtggta tttcaagctg
    40441 ttttaagcca cacatcgtca ttgtttctaa aaatgcgttt tgctgagtac tttcggatat
    40501 attcgcatgc tgtaaaatgc gcgttgtctt ttcaatccca gactgaattt tcgctgccag
    40561 gtaggttgcc ttttcttgcg ttttccactc atctaaattt ccttttctcc attcagaata
    40621 taaatacccc tctatgttgt ctaatggaac cgataatgtc ggcgcgccag cagggttgag
    40681 acataatgtc gaagggaggg ggtaatctac gatttcgcta tatcttctat taatcatggc
    40741 cgtcatttgt ggatgcggtt ttaaaatatc ggggcgatct tttattaaaa aataagcatt
    40801 ccccatgact tcacagctaa aggtatcggt attttgagtg atacgtaaca attcgttttc
    40861 ttcgttttga tccatgatgc gaagaataat cgtgtcatca ttttcatgag gattatgaac
    40921 ctgaaatcta tctctttgcg atgcgcaggc taactctttt aactcaaaaa aaatctctgt
    40981 aaatcgctct cgtgtggggg tgcgatcggc aaacaacatc tcatgtagac aacggtccgc
    41041 ttttgctttg ccagtagaaa aaaagaagtc tttaattttt tcccataaaa ctttccacca
    41101 tgcttctttc gtattccttg gggagttggt aaggatttca ctttttaaaa aaccattccc
    41161 tatagtaatc ggcatattaa tctcacttat actggagtaa aaatgactac ataattgatt
    41221 aaatcaactc tttttatctc aactgcgggc gcatcggatg taatataatt tttaaaagag
    41281 actggcaatc agtataaaac ctgagagctt cgcgtataaa cgcattactg tctgcgatag
    41341 cgtcgctaca ggtaaaaata aaagaaggcc taccgcggat gatgttgtag atttgcaata
    41401 ctggcggcaa cttctttcat gcgtttttta tgccggaggc atgaagttta cccttgaata
    41461 aacttcatgc ctggatgcgt gtggatttgt tagcgttgcg caattaatcg cttatatcac
    41521 tcaccttctt attcaataag cgggaagccc gccagtaaat caacagcatg agtcccatca
    41581 caatggtcag cgtaatgctg gtagccgcgc caaacggcca gtcgcgaata ttcaggaact
    41641 gtaccttaat gacgttacca atcagcaggt ttttcgcgcc acccattaaa tcggagacgt
    41701 agaacaggcc cattgccggt agcatcacga gcaggcaacc ggcgacaatg cccggcatgg
    41761 ttaatggaat aatgatgcgg atgaacgttt gcattttact ggcaccgaga tcgcgagcgg
    41821 cctccagtag cggtttgtcg agcttctcaa tgctggagta gagcggcatg accataaacg
    41881 gcagcaaaat gtaaaccagg ccgataataa cggcgctcgg ggtgaacatg atgcgaatcg
    41941 gcgtatcaat cacgcccagc cacagcagga attcattgag ataaccttta gtgctcagga
    42001 atatttttag cccatagatg cggatcagtg agttggtcca gaaaggaaca atcagcaaaa
    42061 acagcaataa cggacgtatc ttttccggta acttcgccag aaaccaggcg aaaggatagc
    42121 ccagcaccag gcaggagagg gtggcgatca gcgccatatt cagagagtgc aggagcactt
    42181 caaaatagag cggatcgagc aggcgtgcgt agttatccag cgtaaagacc atcttgacga
    42241 aactggcgtc gtcacgggtc agaaagctgg tgccaatgat catcaggttg ggcagaaaaa
    42301 caaacaacac aagccaaccg acgatagtga caatcactac attctggaat ttacttgtgt
    42361 tcttcatcag ccagtacgac ctcccagctt tctacccaac taatggccat tttttggtca
    42421 agtgaatggt cgaagtcagg atcgtcttcg ttgaagaatt cgctgaccat caccattttg
    42481 ccattttcca gttcaaccac cgactccagc gtcatacctt tgtaattgcg ctcgcgcacg
    42541 tagccgataa gcccttcgat gtggttatca tcgttgatct cttcgacgcg tagatcttcc
    42601 ggtcgcagca ggacgttcag tttttggccc agttcgacag cgaaattgac gtatatattg
    42661 cactcccgac cttctacgct ggcgcggacg cgctgttcat caagccgttc aatgacggtt
    42721 gcgtcaaagc ggttaatttc gccgataaaa ccggcgacaa acaggttttt tggctcttca
    42781 tagatttcac gcggcgtgcc gtcttgctca atcacgccat tacgcattac cacgatacga
    42841 tcggacatgg tgagcgcttc ttcctgatcg tgagtgacaa aaacaaacgt gataccgagt
    42901 ttacgctgta atgctttaag ctcgttctgc atttgtttgc gcaatttata gtccagcgcg
    42961 gagagcgatt cgtccagtaa taacaggcga ggtttattca ccaccgcgcg agcgatagcc
    43021 acacgctgct gctgtccgcc ggaaagctgg tgcggtttac gttgtgcaaa ctcttcaagc
    43081 tgcaccatac gcagcgcatc ggtcacgcga ggcgctatct cggcggctgg tgttttttgc
    43141 attcgtaagc caaacgcgac attttcaaac accgtcatat gcggaaataa agcgtagctt
    43201 tgaaatacgg tatttacata acgattttcg gcgggaacgt gggtgatatc ctggttatcc
    43261 aacatgatat gcccggcatc aacggtttcc aggccggcaa tcaggcgaag aacggttgtt
    43321 ttaccgcagc cggaagggcc aagcagcgtg aggaattcgc cattgttaat ggtcaaatcc
    43381 agctgtgaaa tgacctcttt gccatcgaaa cttttgctaa ttcccgacaa aagcaccagc
    43441 ggtgaaagcg aacgcggttg tttattcaat ttcttactct gtcccatgta aacgcaacgg
    43501 atggctgacc gctgcggggt ttgtggttaa ccaccttaat cactcttaat gagggcggtc
    43561 attctacggc aaaccaccgt gatcgccaat ccttgttgcg aattactgac ttagctttat
    43621 agtcagaaag cgtgtcaaag tgaaatattc ttgtttgcag ggataaaagt gacctgacgc
    43681 aatatttgtc ttttcttgct tattaataat gttgtcacga aaagtgaggg tgactgcatg
    43741 gataaactac ttgagcgttt tttacactac gtatcgctgg atacccaatc aaagtcgggt
    43801 gttcggcagg ttcccagcac tgaggggcag tggaagttac tacgtttgct caaacagcag
    43861 ctcgaagaga tggggctggt taacattaca ttaagtgaaa aagggacgtt gatggcgacg
    43921 ctcccggcca atgttgaggg ggatattccc gccattggtt ttatctccca tgtggatacc
    43981 tctccggatt tcagcggtaa aaacgttaac ccgcagattg tcgagaatta tcgcggcggc
    44041 gatatagcat tagggattgg cgatgaggtg ttgtcacccg tgatgttccc ggtactgcat
    44101 caattactgg gacagacgct gattactacc gatggtaaga cattgctggg cgcggacgat
    44161 aaagccggtg ttgcggagat catgaccgcg ctggcggtgc tgaaaggtaa tcctattccc
    44221 cacggcgaaa ttaaagtggc gtttacgcct gacgaagagg tagggaaagg cgcgaagcac
    44281 ttcgatgttg aggaatttgg cgcgcagtgg gcctatacgg tcgacggcgg cggcgtggga
    44341 gaactggagt ttgaaaactt caatgccgcc tcggtgaata tcaaaatcgt cggcaataac
    44401 gtgcatcctg gtacggcgaa aggcgtgatg gtcaatgcgc tgtcgttggc ggcgaggatt
    44461 cacgcggaag tgccggcgga tgaagcgcct gaaaccactg aaggttacga agggttttat
    44521 catctggcca gcatgaaagg caccgttgac cgggccgaaa tgcactacat cattcgcgat
    44581 ttcgaccgta agcagtttga agcgcgtaaa cgcaaaatga tggagattgc caaaaaagtc
    44641 ggcaaggggc tgcatccgga ctgctatatc gaactggtga ttgaagacag ttattacaat
    44701 atgcgcgaaa aagtggttga gcatccgcat attctcgata tcgcccagca ggccatgcgc
    44761 gactgtcata ttacgccgga gatgaaacca attcgcggcg gtacagacgg ggcgcaactg
    44821 tcgtttatgg gcctgccgtg tcctaatctc tttaccggcg gatataacta tcatggtaaa
    44881 catgagtttg tgacgctgga ggggatggaa aaagcggtac aggtgattgt acgtatcgcg
    44941 gagctgacgg gtaagcgcgg ccagtagcga atgttacaca ttgtggtgaa gcgttttatt
    45001 atttatggcg ggatattttc cgccataaat ttttctgcct ggagcgccga atatacgcct
    45061 tcctggtccc agcgccagca acaatctgca gcatgtttta tgaccggcga tgaaacctgc
    45121 atgacgttta ttgatgatgc ggtgaggctg gcctcgcggc aatatggcaa acgctcaata
    45181 cagcttgttc gtagcctgct attacaaagc gatatttatc aatggctggg taaaccggag
    45241 ttaacgccgc aaatgctgct gcgagcgcgg gcaatcatga aaacatttcc ggcgggcact
    45301 tatccgggcg atcgggccga tatgtttgaa cacctggcgg ccttttatgt ttacggtgac
    45361 gatcgccata tagagtattc accgacagag cagtggcgat acgagatcaa ggttgattac
    45421 cgtcagcgga tagcctggca agagcaggca ttaacgtggc gtcttaaaga caaaaagaca
    45481 tcgacggaag cgttggttta taccttaaac aggatgcgcg acgcttattc tgatgcgctg
    45541 gaagagcggg atgtcgaatg tgatagtgcg cgtaaagcct attatttggc gaagatagac
    45601 gcagcggagc ggcagtggct gagcgttatt ttacgggata aaacctggga taatcgtgag
    45661 cgcgtcgcct cttttttgca gcagaaagcg gatattgctt ataatgcagg gcatattagc
    45721 gaggcgatta atgcgctaag tcaggcgcta aaaattgagc aaacgcttta tggcaccgaa
    45781 ttcggcgaaa tgacggttga cagcaataat cttgctggct tttatgcaca gggccatcat
    45841 tataaggaag cgaaagatct ctaccttaaa cttatcgcgt attaccagag ccgtttaacg
    45901 ccaatggcga cggtaatatc acgattacgc ttttatttgc ccgaaaacat cgacctggac
    45961 agtacctccc cctatctccc attgctggaa gaatataaac gtcggcagtc cgacgtatcc
    46021 atggtgttgt atggtatttc gctgctttat aagaataatc aacagcttga acaagcaaaa
    46081 gactttgcgg aacgcgcctt tacgcttgat gccgtagctt atccagcaaa gatgcagtat
    46141 gaacgattac agcaactggc taatattgcc gaaggtcttg gagataacgc gcaggcgcgg
    46201 cgctatcggc aaatgtcatt tcgccatcga atggcccact cgatttatcc gggcgatccg
    46261 caatataacg atttcgccaa acctggcggc gatcgttgtg gatagtttgc gtcagcccgg
    46321 cggtcgccgg gcattgcgat gttcttatcc ttcgaaaaac cagtatccgc tattcaccag
    46381 cgccgccagc atcgcgagga aggaagggtc ttccagcgca tcgccgaagt tttcagcggt
    46441 cagtacaata tgactggtga gcgcttccag agcggggcga tgcggagagt ctattttttc
    46501 gccattcgca tagacttcat cgccgatacg caatacgcga agcccgccga gacgtactaa
    46561 tgcctcgcct tgctttaagg catcgtaaat ttcgtctggc tgatacggcg gctccggcgg
    46621 cgcaatatcc agttcgtggc gtgactgaga gataaactcg ccaagccact gttggaaatg
    46681 cgcgggctga ttgatcaaat cgagcatcat attacgcagt ttatccatct cctgcggcag
    46741 gatatccgcc ggatgtttgc gggacggcat atccggatcg ctgtagtatg tgttgcccag
    46801 atcccgttgc aggacgtaat cggcaaaacc gctgatcagc tcacggctat tgggcgcgcg
    46861 aaaaccgact gaatagttca tggcgttttc cagcgcatac ccttcatgcg ggaatccagg
    46921 cggaatatac agaatgtcgc ccggctccag ctcttcgtca ataatggcct cgaacggatc
    46981 gacttgtaac aggtcgggat gcgggcagtg ctgacgcatt tgcagctttt cgcccacgcg
    47041 ccagcgacgg cgaccggttc cctggataat aaacacatca tactgatcca gatgcgggcc
    47101 aacgccgcca ccgggaacgg aaaaggagat catcagatcg tcgatacgcc agtccggcag
    47161 agcgcggaac gggcgcatca gcgcggcggt gggttcatgc cagtggttta ccgcctgtac
    47221 cagcagcgac cagttgctct cacccagatg atcgtagctt tcgaaagggc catggctgac
    47281 ctgccatttg ccatcctgat ggctaacgag acggctgtcg atttcgcttt ccatcgccag
    47341 ccccgccagc tcatccggcg agagcggatc aataaagttg gtaaacccac gttttaagac
    47401 caccgggcgt ttttgccagt ggcgttcaag aaagtcgggc cagttaagag ttaattggta
    47461 ttccatgtta agtatccgca ggctggtatc tgacaccgat tataacggat gcttaacgag
    47521 atgcgtggaa gaacgcacag aaatgtttat tcctctttct gtgtgggatg ctgtcggcca
    47581 aaaacgacct ccatacgggc gccaccgagc agactgtcgc tggcaatgat ctgcccggcg
    47641 tattgttccg taatctcgcg cgcgacagcc agccccacgc cttgtcctgg tcgtagggta
    47701 tcggcgcgct gaccgcgatc aaacaccagg gaacgtttgc tgtggggtat gcctgggccg
    47761 tcatcttcga cgaaaatatg caaatgatcg tcggtctggc gagccgaaat ctcgacaaac
    47821 tccagacaat atttacaagc gttgtccagt acgttgccca ttacttcgac aaagtcgttt
    47881 tgctcgccga caaaactgat ctctggtgaa atatccatac tgatattcac ccctttacgc
    47941 tgataaactt tattgagcgc ggagatcagg ttatctaaca acggcgcgac gggatgcagt
    48001 tcgcggctta acaacacgcc gctaccgcgc atactggcgc gatgcagata atagccgatc
    48061 tgctgggaaa tccgactgat ctgttccagc atcaccggtt cagctttgct gacgctcatc
    48121 ttttcgttgc gtaaagagcg taacgtactc tgcaaaaccg cgagcggcgt ttttaaactg
    48181 tgcgtcaggt cggttagggt cgtgcggtat ttgttataac gttcgcgctc gcttttgagc
    48241 agttgattaa ggttgcgcac aaggctggtc agctcacgcg tcgtctccgg attgagcatt
    48301 tcgcggtgat gatcttcaag ttcgcggact tcccgcgcca gcgcctcgat agggcgtaag
    48361 ctccaccagg cggcgatcca cagtaaagga atgactaaca gtaaattggc ggccagcacg
    48421 tatacgaacc agctccacac catataggag cgttttagct ctatcggaat ggtatcgacc
    48481 accacgatgg ttaactgcgg catccgcgtc gtggcaggat aaatatttac cgctaccgag
    48541 tgggtcatct ccgcatcatc gtcatcttca cgtacttctt tgagtttttc ctgcgcggaa
    48601 tggtcctcgc tcaacagcgt gctggtggcg tctacgttgg tttcaatttc atggaagccg
    48661 ttcgttttta accattccgg ttgaatgctt ttaatcagcc aggggatgtt gcgctgcgtc
    48721 cataataatt tgcccgtttc atcgtaaatc agcgtcatgg tcgggctttg catgtccaga
    48781 ttttcaggca gctcaacgct gattttatta ttttcccatt tggcgagggt ataaaacagg
    48841 ttgctttcgc cgcgcagcag acgaaacgtg gttttatcaa aacttacgct atagccgacc
    48901 agcgccacta tgccatatgc cagagaaagc accagcacga cgccggctgt cgccagcaaa
    48961 aaacgaaccc gcagcgacag cggcagaaaa tggcgagcaa atttattcat tagcgcaatt
    49021 caaaaagata tccttgtccg cgtacggtgg taatgacatc gtgcggatac tgggcctgta
    49081 tttttttccg cagacgcccc atgagaacat caatggtatg actttcccgc agttccgcat
    49141 ccggatacag ctgaagcatc agagaatctt tgctgaccac tttaccgttg ttacggataa
    49201 gcgtttccat aatggtgtat tcgaacgccg tgagtttgat gacctcttca ttgacggata
    49261 attcccggcg tgagagatcc acctggaaag gcgagatgtt gatcacctgg gaggccagac
    49321 cgctattacg gcgcattaac gcctgcatac gcgccattac ctcttcgatg tggaatggct
    49381 tcgtcacgta gtcatcggcc ccggagctga gaacctcgac tttatcctgc cagccttcgc
    49441 gcgcggttaa caccagaacc ggcagtgaaa catcactgct gcgccagcgg cgtattaagg
    49501 aaaggccgtc ttcatccggc agacctaaat cgacaatagc gatatccgga aggtgttcat
    49561 taaggtagta atcagcttcc ctggcatctt ctgcggcatc gacctggtga cctgaatcct
    49621 ggagctgaac cttcaggtgg tggcgtaata atgcattatc ctctacaacc agtacgcgca
    49681 tcatctcttc tcccttgtgt taacaataag aacagtctag cgttgattat ggtgctttgg
    49741 ggataaacag ttaataaacc agacaaatag tcaccctctt tctgaagaaa agagggtgag
    49801 gcacacatta tttaagttcg tcgaccagat tcacagcgcg accgatataa tttgccggcg
    49861 tcatggcttt aaggcgcgtt ttttctgctt ccggcagggc cagactatca ataagctgtt
    49921 tcattccttc ggcatcgaca cgcttgccac gggtcaactc tttcagtttt tcatatggtt
    49981 tttcaatgcc atagcggcgc atgacggtct ggatcggttc ggctaatact tcccagttgt
    50041 gatccagttc gtcaagcaga tgatcgcggt tcacttccag cttgctgacg cccttcaggg
    50101 tcgactgata agcgataagc gcatagccga tgccgacacc caggttacgc aggacggttg
    50161 agtcggtcag atcgcgctgc cagcgggaaa ccggcagttt gtttgccaga tggtgcaaca
    50221 ctgcattaga cagaccgagg ttgccttctg agttttcaaa gtcaatgggg ttaactttat
    50281 gcggcatggt agaagaaccg atctctccgg cgatggtttt ctgtttgaaa tggttcaacg
    50341 caatatagcc ccagacatcg cgatcgaaat cgatcaggat ggtgttaaag cgcgcgatac
    50401 agtcaaacag ttccgcaata taatcatgcg gttcaatctg ggtggtgtaa gggttccact
    50461 ggatgcccag cgaggtgacg aactcttcgc tgaactgatg ccagtcaact tccggatagg
    50521 cggcgatatg cgcgttatag ttgcctacgg cgccgttaat tttaccgagg atctccacct
    50581 gattgagctg gcggaactga cgctccatcc gatacgccac gttcgccatc tctttaccca
    50641 gagtggaagg tgttgccggc tggccgtggg tgcgggagag cagaggaata tcgcgatact
    50701 gcgtggcgag atctttaacc gcgttaatca cctgacgcca gtaaggcagg atcacttcat
    50761 cgcgcgcagt tttgagcatt aacgcgtgcg acaggttgtt aatatcctca gaggtgcagg
    50821 caaagtggat aaattcggaa acgtcatgta gcgccgggat cgcggcggct ttttctttca
    50881 gaaaatactc aaccgctttc acatcgtgat tcgtggtgcg ctcaatggtt ttaatgcgcg
    50941 cggcatcttc ttcattgaag tttgccacaa gcgtatccag gtaaccgttt gcgtcggcag
    51001 caaaagcagg aacttccttg atcgctgcgt gcgcggctaa tttctgcagc caacgtactt
    51061 cgacttgtac acgaaatttc agcaaaccgt attcgctaaa aattccgcgc agcgcgctga
    51121 ctttatcgcc gtagcgtcca tcgacagggg aaacggcggt cagtgaggat aattccatag
    51181 atcataactc cggggttaaa taagcaagaa tttgttttgc ctgagtcgtc aggcgatgac
    51241 gagaaaacat aagctgtagg cgaccaccgc ctacctgatg ccagagcacg gctgcacgga
    51301 tgcctgccag tagcgaggcg cggactttgg cctgcacctg cggactttgc agaacggccg
    51361 gggagcccgt cacctgaatg cgcgggccca atgggctaat cacatccacg tagatgcccg
    51421 ccatggcgct cattaacgtg tctgactgta aatcaaaatg gtcaagctgg cgctgcaggc
    51481 cgttaatgcg atcgcctaac gtattcaacg cgcctttggc ggatgacagc ttgcgctcca
    51541 gcaccatcag gctaagcgta taacgcgtca gttcggcgtt aagtccttgt cggctgctgg
    51601 cattcagcac gccgagcagt gtttccagac caagacgcag gttagcttcg ctgccgccga
    51661 acacgcccag agtagaactg ggattcatat caatgacact gttgagtgaa acgtgcaacg
    51721 cgtcggcatc acagtgtccc tggtgcgcca gttgttgcac caggcgtgcc gactggcaaa
    51781 tgccagacag cgcgagggtg atgtcataat aattctttgc cacaatcact gcttccttgt
    51841 atcaaataaa atacacttca tcttttaagc cgctttgagg tgacttgaat ggtgttgtgt
    51901 attgaataat cagaccgtca gcggcagtcg ctgctcgata atgccgccgc ccaggcagac
    51961 ttctccgctg taaaagacag cggactggcc cggcgtaacg gcggcaaccg gctcgtcaaa
    52021 aatgacctcg atacgatcgt catccagcgc gttaatcgtg cacggaatat cggtctggcg
    52081 gtagcgggtt tttaccgtac agcgcagggt gccggtgaac ggttcgcgat cgacccaatg
    52141 tagctgctgg gcgatgaggc ctaccgacat caggcgtggg tgctcatgcc cctgggcgac
    52201 aattaacaca ttgttttcaa cgtctttatc caccacatac caggggtctt cgctaccgtc
    52261 tttggtgccg ccaattccca gccctttacg ctgaccgagc gtatgataca tcagaccctg
    52321 atgctcgccg atttcatcgc cgtcaacagt aatgattttc cccggctgcg caggcagata
    52381 gcgccctaaa aagtcgcgga atttgcgctc gccgataaag cagataccgg tagaatcttt
    52441 tttcttggcg gttaccagcc ccaaatcttc ggcgatttta cgcacctgcg gtttttccag
    52501 ctcgccaacc gggaacagac tttgcgcaat ctgctcatgg ccaagcgtat agaggaagta
    52561 gctctgatct ttgttaccgt cgagcccgcg caacaaccgg cttttgccgt ttacatccgc
    52621 gcggcgaacg tagtgaccgg tggcgatata gtcggcgcct aaatcttctg cggcaaattc
    52681 aaggaaggct ttaaatttga tctctttatt gcacagaata tccggattcg gcgtacggcc
    52741 cgctttgtac tcttcaagga acagttcaaa gacgttatcc caatattctg cggcaaaatt
    52801 aacggtatgc agttcaatgc caagcttgtc gcacacggcc tgcgcgtcag ccagatcggc
    52861 tgccgcggtg cagtattcct caccatcgtc ctcttcccag ttcttcatga acaggccttc
    52921 tacctgataa ccctgttgtt gcaacagcca ggcggaaacg gaggaatcga caccgccgga
    52981 catgccgacg atcacttttt ttgggctttc tgacattgga atactcgcga cattgaactt
    53041 caaggcggcg tattctatca cgcagccctt tacttgacac cctctgtaaa cggccagtta
    53101 aattcgccca ctatagataa ggggtaacgt tgtcccgttt gataactgcg aatgctttca
    53161 gccaccagcg gagaacgtaa attcggcgcg ttcagaatct cgtcggcgct cacccaacgg
    53221 cagcaatcga tgtcattgtc atggggggcg gtcgcgcaaa tatgatcaag cttgatagcg
    53281 aataaaaagc gcaggaacgg ggttttatcc ggcgcaatcc actgatgcat acggataaaa
    53341 tactgtggtt gcgccgtgat gccagtctct tcccacagtt ctcgcgcggc ggcctgcgcc
    53401 agcgtttcat ctgcctccag gtgtccggca ggttgattcc ataacgattt accgttgatg
    53461 gtctcttcca ccaccagaaa tttatcttcg gcatgtacga tgcaggcaac ggtcacgtgc
    53521 ggcttgaaca taggcatcct tattaaagcg gtttatcaat gtggtcatag atcgcgtcaa
    53581 gctgtttcag acgctcgtta taagcttttg tcaggcaggt gacgtcggcc ttgcactgct
    53641 gacgctgttt aagccagctc tgctgggcgt cctgcagcgc gccgcgactg cccatcgcga
    53701 acaacccttt cagaaactga tatttggtgt gcatttccac gtctttatca ttcagcgtca
    53761 ggtgcgcgca gatagccttt tcatccgcag cctgcgcttt ctggcagtcg aagctggccg
    53821 cattaacgga taacggtgtt aataaagcaa aagcaatgag aagccgtttc atctgtcttt
    53881 ctcctgtgcg atctcgcacc actgtccatt atcgaggccg ttgagcgtgt agtcgcccat
    53941 gctgtaacga attaatcgta gagtgggatg accgacatgc gctgtcatgc gtcttacctg
    54001 gtggttgcgg ccttcatata aggtgacttt tagccaactg gtgggaatat tcttccgttc
    54061 gcgaatcggc ggggtgcgcg gccacagcca gtcaggctcc gcgacaatct caataccggc
    54121 gggcagggta gggccatcgt tgagcgtgac gccagtacga agcgcctgca gcgctgcatt
    54181 atccgggatg ccttctacct gaacatagta aatcttgccg gtgcgtttgc ccggttgcgt
    54241 gaggcgcgcc tgcagcgcgc cgtcattagt cagcaccaaa agcccttcgc tgtcgcggtc
    54301 caggcggcct gcggcataaa cgccttgcac aggaataaaa tcttttaacg tgcggcgacc
    54361 tgcttcatcc gtgaactgcg gcaacacatc gtaaggttta ttgaacaaaa ccacgcgttt
    54421 tggctggttt tctttccgtg atttagatgc ttgtcgtgag ctgaatcgct taacgtagtg
    54481 atttctaaaa gaagtttttt gcatggtgtt ttcagaactt attaattgcc gcattatagc
    54541 gcaataatga gtgtctttca tggcggcaaa caatagggta gtattgacat gctcattaca
    54601 aaacattaac aaaaaattgc tctaacgcag tcgtgcagca ggacgccatt gcacatgcag
    54661 cgcgatgaca gacgagcaaa ccagaagcgc tcgaaggaga ggtgaatgga aagcaaagta
    54721 gttgttccgg tggaaggtaa gaagatcacc ctgcaaaacg gcaaactcaa cgttcctgag
    54781 aatccgatta tcccgtttat tgaaggcgat ggtatcggtg ttgatgtcac tccagccatg
    54841 cttaaagtgg tcgatgccgc cgtcgagaaa gcctataaag gcgagcgtaa aatttcctgg
    54901 atggaaattt acaccggaga aaaatccaca caggtttacg gccaggatgt ctggcttccc
    54961 gctgaaaccc ttgatttaat tcgtgactac cgcgtagcga ttaaaggtcc attgaccacg
    55021 ccggttggcg gcggtatccg ctctctgaac gttgccctgc gtcaggagct tgacctgtac
    55081 gtttgtctgc gtcccgttcg ttactatcag ggcacgccaa gtccggtgaa acatccggag
    55141 ctgaccgata tggtcatctt ccgtgaaaac tctgaagaca tctacgccgg aattgaatgg
    55201 aaagctgact ctgcagacgc tgagaaagtg atcaagttcc tgcgcgaaga gatgggcgtg
    55261 aagaaaattc gcttcccgga gcactgcggt atcggtatca aaccgtgttc tgaagaaggc
    55321 actaaacgtc tggttcgcgc ggcgattgaa tacgctatta ccaacgatcg cgattccgtc
    55381 acgctggtac ataaaggcaa tatcatgaag ttcaccgaag gcgcgtttaa agactggggc
    55441 taccagttgg cgcgcgacga gttcggcggt gagcttattg acggcggtcc gtggctgaaa
    55501 attaagaacc cgaacacggg taaagagatc gtggttaaag acgttatcgc cgatgcgttc
    55561 ctgcaacaaa tcctgttgcg tccggcggaa tacgacgtta tcgcctgtat gaacctgaac
    55621 ggtgactata tttccgatgc cctggcggct caggttggcg gtatcggtat tgcaccgggt
    55681 gcgaatatcg gcgacgaatg cgcgttgttt gaagcgactc acgggactgc gccgaaatat
    55741 gcgggccagg ataaagtcaa cccaggctcc attattctgt ctgcggagat gatgctgcgc
    55801 cacatgcagt ggttcgaagc ggcggatctg attgttaaag gtatggaagg cgcgattgcc
    55861 gcgaagaccg tgacctatga ctttgaacgc ctgatggacg gcgctaagct gctgaaatgt
    55921 agtgagtttg gcgacgcgat tatcgcaaat atgtaatatc gataattgtt aaaaacaaaa
    55981 acgggggctt aacgtcccc
//
LOCUS       DAJVKX010000011        55284 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000011 DAJVKX010000000
VERSION     DAJVKX010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 55284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55284
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.011"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            268..813
                     /gene="sthA"
                     /locus_tag="OPY25_000640"
     CDS             268..813
                     /gene="sthA"
                     /locus_tag="OPY25_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein SthA"
                     /protein_id="HCS0926336.1"
                     /translation="MFNKKIIILAMLTAVASTPVFAQNTITFNGKIYDQACTVQVNGS
                     TDTTIDLGNYSKERIAEKGATTDYVPFTVSLVSCPEAGTGVPTQAMFRFHGATDDSNP
                     TYFKNADEGSETGAAGVGISIQNASHSDVTDNTDDAAVSLPTDGSTADFTYYAAMAND
                     GSATVTGGDVSTQVTYTVSYQ"
     gene            884..1567
                     /locus_tag="OPY25_000641"
     CDS             884..1567
                     /locus_tag="OPY25_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial assembly chaperone"
                     /protein_id="HCS0926337.1"
                     /translation="MKHIKKSVLVVLLTSHVAHASIVVGGTRLVFDGNNDESSINVEN
                     KDSKANLVQSWLSVADPQVTNKQVFIITPPLFRLDAGQKNSIRVIRSGAPLPADRESM
                     YWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
                     TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLSSTAAPHGTVTWRLISDYGM
                     SLEPHSGSF"
     gene            1613..4149
                     /locus_tag="OPY25_000642"
                     /pseudo
     CDS             1613..4149
                     /locus_tag="OPY25_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463449.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein"
     gene            4167..4724
                     /locus_tag="OPY25_000643"
     CDS             4167..4724
                     /locus_tag="OPY25_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein SthD"
                     /protein_id="HCS0926338.1"
                     /translation="MNMNRFAALAALLTFTGLASWSPSISAAYNTADAVDINVTGLIY
                     ADPCTVTVPDTISLGQYARADIAVAGGNTATIPFTIKMTNCPATTTKAAISFNGVPYP
                     DPNYASAIYANSAANPAQDLGLQLFNLDSKSLVNLANNVTYTVDINSNTHEANLPVAA
                     RMYTPYGKVTAGDFTSVVTITIAWQ"
     gene            4765..5849
                     /locus_tag="OPY25_000644"
                     /pseudo
     CDS             4765..5849
                     /locus_tag="OPY25_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463447.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
     gene            complement(5907..7256)
                     /gene="creD"
                     /locus_tag="OPY25_000645"
     CDS             complement(5907..7256)
                     /gene="creD"
                     /locus_tag="OPY25_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HCS0926339.1"
                     /translation="MLKSPLLWKMITLGGAMILLLIPLMMVRHTIVERADYRSHVEAA
                     IRQSTSGPQKVVGPLVAVPVTELYTVLEEEKEVQYKRSYLYFWLPESLLVEGNQNVEA
                     RKIGIYQGQVWHTDMAIKAEFDVARLHELNRPNITLGKPFIVVGVGDARGISAVKAPQ
                     VNGEMLTVEPGTGLPESREGIHIPLPDSQWATRNLTLAMSLNLSGTGSFSLVPVGRSS
                     EMTLTSNWPHPNFVGDFLPGKREISGSGFQAQWQTSRFATNLGEQFADAQKVDWDNLP
                     AFSVAVSTPADQYQLTDRATKYAILLITLTFMAFFVFETLTGQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHIGFTPAWIAASLVGALMNSVYLQAVLKGWRNSVLFTLALLALDGVM
                     WGLLRSEDSSLLLGTGVLLLALGGVMFLTRHLDWYSLSCQQRKSLPPVKDDELRLWK"
     gene            complement(7314..8738)
                     /gene="creC"
                     /locus_tag="OPY25_000646"
     CDS             complement(7314..8738)
                     /gene="creC"
                     /locus_tag="OPY25_000646"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HCS0926340.1"
                     /translation="MRIGMRLLLGYFLIVAVAAVFVLSIFVQEIKPGVRRATEGTLID
                     TATLLAALARDDLLSGNPTDGQLAKAFAQLQHRPFRANISGIVKVRNEYHVYMTDAQG
                     KVLFDSENKAVGQDYSRWNDVWLTLRGQYGARSTAKDSADPNSTVMYVAAPIISDGRI
                     IGVLTVGKPNAAMAPVIKRSERRILWASAVLLGIALAIGAGMVWWINRSIARLTRYAD
                     SVTENRPLALPALGSSELRKLAQALESMRIKLEGKNDIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPADVVTRFTENILAQNTRMQALVETLLRQARLENRQDIPLAPVAVDELF
                     TQLSEARSIQLAAKKITLTLRPSSLVVVADAELLAQALGNVLDNAIDFTPENGVITLS
                     AQPMGEKAILQVTDSGCGIPDFALPRIFDRFYSLPRENGRKSSGLGLAFVSEAARLLN
                     GEVTLCNRPEGGVLASLTLHRHFT"
     gene            complement(8738..9427)
                     /gene="creB"
                     /locus_tag="OPY25_000647"
     CDS             complement(8738..9427)
                     /gene="creB"
                     /locus_tag="OPY25_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HCS0926341.1"
                     /translation="MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKAR
                     QQRPDAVILDVGLPDISGFELCRQLLERHPALPILFLTARSDEVDRLLGLEIGADDYV
                     AKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFDLNEPAAQIAWFGTPLSLTRYEF
                     LLLKTLLLSPERVYSCQQLMDIVWSDAQETFDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRSI"
     gene            complement(9440..9913)
                     /gene="creA"
                     /locus_tag="OPY25_000648"
     CDS             complement(9440..9913)
                     /gene="creA"
                     /locus_tag="OPY25_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HCS0926342.1"
                     /translation="MKYKSLVLFSILLLLGQSARAEQIGSVDTVFKMFGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDKIKNGKAQGE
                     VVFKKRTSLIFKSLQAVRFYDEKRNTLAYLAYSDKVVDGSPKNAISAVPVMPWRQ"
     gene            10125..10994
                     /gene="robA"
                     /locus_tag="OPY25_000649"
     CDS             10125..10994
                     /gene="robA"
                     /locus_tag="OPY25_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HCS0926343.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFSQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTVPEHQFVTLEDTPLLGVTQSYSCSLEQISDFRHEMR
                     VQFWHDFLGHSPTIPPVLYGLNETRPSMEKDDEQEVFYTTALPQEQADGYVQSAHPVL
                     LQGGEYVMFTYEGLGTGVQDFILTVYGTCMPMLNLTRRKGQDIERYYPSEDTKTGDRP
                     INLRCEFLIPIRR"
     gene            complement(10991..11638)
                     /gene="gpmB"
                     /locus_tag="OPY25_000650"
     CDS             complement(10991..11638)
                     /gene="gpmB"
                     /locus_tag="OPY25_000650"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HCS0926344.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVGERAR
                     SLGITHIISSDLGRTKRTAEIIAQACGCDITFDFRLRELDMGVLEKRQIDSLTEEEEG
                     WRRQLVNGTQDGRIPGGESMQELSDRVHAALASCLELPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRIDYQESQWLASGWVVETAGDVSHLDTPALDELQR"
     gene            11686..12021
                     /locus_tag="OPY25_000651"
     CDS             11686..12021
                     /locus_tag="OPY25_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF84 family protein"
                     /protein_id="HCS0926345.1"
                     /translation="MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQ
                     PFGSEETRAGARNRVGNARRLHPQADFWIGRKEGAIGVFTAGKLTRSSVYYQAVILAL
                     SPFHNAVYR"
     gene            complement(12123..12449)
                     /gene="trpR"
                     /locus_tag="OPY25_000652"
     CDS             complement(12123..12449)
                     /gene="trpR"
                     /locus_tag="OPY25_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HCS0926346.1"
                     /translation="MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLT
                     PDEREALGTRVRIIEELLRGEMSQRELKTELGAGIATITRGSNSLKSAPVELRHWLEQ
                     ILLKSA"
     gene            complement(12507..14444)
                     /gene="sltY"
                     /locus_tag="OPY25_000653"
     CDS             complement(12507..14444)
                     /gene="sltY"
                     /locus_tag="OPY25_000653"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HCS0926347.1"
                     /translation="MDRAKPFVWRLVAASVCLLTFCHLARADSLEEQRNRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRKITDDLMNQPAIAVTQFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWSTGQTEAAWQGAKDLWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPAEYQTIASAI
                     ITLANDPNNVLTFARTTGATDFTRQMAEVAFASVARQDAENARLMIPSLVQAQKLNEE
                     QTQALRDIVAWRLMGNDVTDAQAKWRDDAIMRSQSTSLIERRVRMALGMGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGRDAEAKEILHALMQKRGFYPMVAAQRLGEEYT
                     LKIDKAPANVNSALTQGPEMARVRELMYWNLDNTARSEWANLVKSRSKSEQAQLARYA
                     FNQHWWDLSVQATIAGKLWDHLEERFPLAYNDLFTRYTRGKDISQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPDYRGPGQLLEPETNINIGTSYLQYVYQ
                     QFGNNRIFASAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRHFMGQKEALMSDSEWQRRY"
     gene            14653..16320
                     /gene="ettA"
                     /locus_tag="OPY25_000654"
     CDS             14653..16320
                     /gene="ettA"
                     /locus_tag="OPY25_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HCS0926348.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGLDKDIEGEARPQPGIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKV
                     EKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASAEAARRKSIEKELEWV
                     RQGAKGRQSKGKARLARFEELNSVEYQKRNETNELFIPPGPRLGDKVIEVSNLRKSYG
                     DRVLIDDLSFSVPKGAIVGIIGPNGVGKSTLFRMMSGQEQPDSGTITLGETVKLASVD
                     QFRDAMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNVLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGAEALEPKRIKYKRIAK"
     gene            complement(16438..17670)
                     /gene="nadR"
                     /locus_tag="OPY25_000655"
     CDS             complement(16438..17670)
                     /gene="nadR"
                     /locus_tag="OPY25_000655"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463436.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HCS0926349.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRRQKNIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGYDD
                     TRDRGLFEDSAMSQQPTVSDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKAFMAEKGIQPSWIYTSEEADAPQYLEHLGIETVLVDPERTFMNISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     MALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWIADGLRSLGSSVDRKAFQNLLVEMLKENNIEFVHVKEADYD
                     GRFLRCVELVKEMMGEQG"
     gene            complement(17821..19203)
                     /gene="radA"
                     /locus_tag="OPY25_000656"
     CDS             complement(17821..19203)
                     /gene="radA"
                     /locus_tag="OPY25_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCS0926350.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACQAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVSKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAEQMKTLYVTGEESLQQVAMRAHRLGLPTANLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADIQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKPPEGMQVFGVKKL
                     ADALSVFDDL"
     gene            complement(19287..20255)
                     /gene="serB"
                     /locus_tag="OPY25_000657"
     CDS             complement(19287..20255)
                     /gene="serB"
                     /locus_tag="OPY25_000657"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HCS0926351.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQTKLGAAMVIVAAWCVEDYQVIRLAGSLTPRATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEKVAEVTERAMRGELDFTASLRS
                     RVATLKGADADILRQVRGNLPLMPGLTQLVLKLEALGWKIAIASGGFTFFADYLRDQL
                     RLTAAVANELEIMDGKFTGHVIGDIVDAEYKANTLLRLAQEHDIPLAQTVAIGDGAND
                     LPMIKAAGLGIAFHAKPKVNEKTEITIRHADLMGVFCILSGSMNQK"
     gene            20372..21016
                     /locus_tag="OPY25_000658"
     CDS             20372..21016
                     /locus_tag="OPY25_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463433.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HCS0926352.1"
                     /translation="MARAKLKFRLHRAVIVLFCLTLLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNIAPLMRSETPDENRINAVLRQLTQESRILDAGVYDEQGDLITR
                     AGESVNVRDRLALDGKKAGSYFNQQIVEPIQGKNGPLGYLRLTLDTHTLATEAKQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEEREEKE"
     gene            21050..22066
                     /gene="lplA"
                     /locus_tag="OPY25_000659"
     CDS             21050..22066
                     /gene="lplA"
                     /locus_tag="OPY25_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HCS0926353.1"
                     /translation="MTTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     HIVLAALNSLGVMADASGRNDLVVKTPDGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVANLTELLPGITHEQVCQAVTEAFFAHYGERIDA
                     EVISPDKTPDLPNFTETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGVI
                     TRAQAFTDSLNPAPLEALAGRLQGCQYRADKLQETCEALIATFPEQESELRELANWVA
                     GAVR"
     gene            complement(22157..22642)
                     /locus_tag="OPY25_000660"
     CDS             complement(22157..22642)
                     /locus_tag="OPY25_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCS0926354.1"
                     /translation="MSNYRRYYINGGTWFFTVNLKNRKSDLLVRQIAELRSAIRRVKN
                     TKPFQIDAFVVLPEHLHCIWTLPENDCDFSSRWRELKKLFTKSIMRHDVWQPRFWEHT
                     IRDEKDFRRHVDYLYFNPVKHGWVRRVQDWPFSTFHRDVRNGVYPVDWAGEVRDLDAG
                     E"
     gene            complement(22849..23568)
                     /gene="deoD"
                     /locus_tag="OPY25_000661"
     CDS             complement(22849..23568)
                     /gene="deoD"
                     /locus_tag="OPY25_000661"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCS0926355.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKHIAETFLEDVREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVRMDVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLF
                     YSPDGEMFDVMEKYGVLGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(23778..25001)
                     /gene="deoB"
                     /locus_tag="OPY25_000662"
     CDS             complement(23778..25001)
                     /gene="deoB"
                     /locus_tag="OPY25_000662"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCS0926356.1"
                     /translation="MKRAFIMVLDSFGIGATEDADRFGDVGSDTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLVKAHEGSTGKIAAGMDGNADVIGAYAWAHELSSGKDTPSGH
                     WEIAGVPVLFDWGYFSDHENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTEGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKQGHVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATLKEMKEAGDKTIVFTNFVDFDSSWGHRRDIAGYAAGLELFDRRLPELME
                     LVGEDDILILTADHGCDPSWTGTDHTREHIPVLIYGPKVKPGSLGHRETFADIGQTLA
                     TYFGTSPMDYGKNML"
     gene            complement(25053..26375)
                     /gene="deoA"
                     /locus_tag="OPY25_000663"
     CDS             complement(25053..26375)
                     /gene="deoA"
                     /locus_tag="OPY25_000663"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HCS0926357.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYL
                     PTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDS
                     IDGQRPLAVIHAKDEASWQEAAKAVKAAIILDDKAPASTPSVYRRITE"
     gene            complement(26498..27277)
                     /gene="deoC"
                     /locus_tag="OPY25_000664"
     CDS             complement(26498..27277)
                     /gene="deoC"
                     /locus_tag="OPY25_000664"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCS0926358.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTNEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPDIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVD
                     VVFPYRALIAGNEQVGFDLVKACKDACAAANVLLKVIIETGELKEEALIRKASEISIK
                     AGADFIKTSTGKVPVNATPESARIMMEVIRDMGVSKTVGFKPAGGVRTAEDAQKFLAI
                     ADELFGANWADSRHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            27537..29087
                     /locus_tag="OPY25_000665"
     CDS             27537..29087
                     /locus_tag="OPY25_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HCS0926359.1"
                     /translation="MPASCETALQQRCQQIVTSPVLTPEQKRHFLALEAENALPYPTL
                     PEDARQALDEGVICDMFEGHAPFKPRYVLPDYARFLANGSQWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDAIDIRIKRFWRYLDRTLPDAFMHA
                     NIGPADTPVTRAILRADAELKQVAPNLTFIYDAEITPDDLLLEVAKNICECSKPHISN
                     GPVNDKIFTKGHYGIVSCYNSLPLAGGGSTLVRLNLKAVAERSTSVDDFFSRTLPHYC
                     RQQIAIINSRCEFLYEKSHFFENSFLVQEGLIDPERFAPMFGMYGLAEAVNLLCENAG
                     LTARYGKNETANELGYRISAQLADFVENTPVKYGRKQRALLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAFYHAGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLAKFRAEGSRTNTTWLGEEAARNTRILERQPRVVSH
                     EQQMRFSQ"
     gene            29059..29922
                     /locus_tag="OPY25_000666"
     CDS             29059..29922
                     /locus_tag="OPY25_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HCS0926360.1"
                     /translation="MNNRCALVSKIIAFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVSQCPHHALSIDGGKVVWRSDVCEQCDTCLKMCPQQATPMAQTMSIDDV
                     LRHIRKASLFIEGITVSGGEATTQLPFIVALFTALKADPQLQRLTCLVDSNGQLSETG
                     WQKLLPVCDGVMLDLKAWKSECHHRLTGRDNTHIKHSIRFLAARGKLAELRLLVIPGQ
                     VDYAAHIDSLAAFITSLGEVPVRLNAFHAHGVYGEAKAWPGATPQEVERLADGLRARG
                     VAKLILPALYL"
     gene            complement(29955..30728)
                     /locus_tag="OPY25_000667"
     CDS             complement(29955..30728)
                     /locus_tag="OPY25_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCS0926361.1"
                     /translation="MSWRFIDTHCHFDFPPFTGDERASIQRACEAGVEKIIVPATEAA
                     HFPRVLALAARFPSLYAALGLHPIVIERHADDDPDKLQQALAQQQNVVAVGEIGLDLY
                     RDDPQFARQERFLDAQLQLAKRYDLPVILHSRRTHDKLAMRLKRQSLPQTGVVHGFSG
                     SLQQAERFVQLGYKIGVGGTITYPRASKTRDVMARLPLDALLLETDAPDMPLKGFQGQ
                     PNRPEQAARVFDALCELRPEPAEVIADTLYRNTVTLFRL"
     gene            complement(30725..31798)
                     /locus_tag="OPY25_000668"
     CDS             complement(30725..31798)
                     /locus_tag="OPY25_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HCS0926362.1"
                     /translation="MGQRIPVTLGNIAPLSLTPFRSGRMALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFHLYFGTSAGAQNLSAYLCNQPGYGRKVIMRYTTRREFFDPLRFVRGGN
                     LIDLDWLVESTAARMPLQMDTSARLFDSGKSFYMCACRGDDYTPGYFSPTKQNWLDII
                     RASSAIPGFYRTGVTLEGINYLDGGISDAIPVQEAAKRGAKTIVVIRTVPSQMYYTPQ
                     WFKRMERWLGESSLQPLVNLVQHHETSYSAIQQFIEKPPGKLRIIEIYPPKPLHSMAL
                     GSRIPALREDYKTGQLCGRYFLATVGKLLAATPPLLRHSSRIAVPETVVVPPAPVAND
                     THVAEVISAPQANDTTFTDEDLA"
     gene            complement(31922..32083)
                     /locus_tag="OPY25_000669"
     CDS             complement(31922..32083)
                     /locus_tag="OPY25_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HCS0926363.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIVLFLV
                     SLFMGRKRP"
     gene            complement(32212..32829)
                     /gene="osmY"
                     /locus_tag="OPY25_000670"
     CDS             complement(32212..32829)
                     /gene="osmY"
                     /locus_tag="OPY25_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HCS0926364.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAFAENATTDKAQSGTETAG
                     QKVDSSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVETNQKVVTLSGFVESQAQ
                     AEAAVKVAKGVEGVTSVSDKLHVRDNKEGSVKGYAGDTATTSEVKAKLLADDLVPSRK
                     VKVETTDGVVQLSGTVETQEQSDRAESIAKAVDGVKSVKNDLKVQ"
     gene            complement(33231..34820)
                     /gene="prfC"
                     /locus_tag="OPY25_000671"
     CDS             complement(33231..34820)
                     /gene="prfC"
                     /locus_tag="OPY25_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCS0926365.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSSQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQTGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVQGASNEFDEELFLAGEITPVFFGTALGNFGVDHMLDGLVAWA
                     PAPMPRQTDTRTVEASEERFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTGKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     ARLKSEYNVEAIYESVNVATARWVESADAKKFEEFKRKNETQLALDGGDNLTYIAPTM
                     VNLNLTQERYPDVQFRKTREH"
     gene            complement(34912..35589)
                     /gene="yjjG"
                     /locus_tag="OPY25_000672"
     CDS             complement(34912..35589)
                     /gene="yjjG"
                     /locus_tag="OPY25_000672"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HCS0926366.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHARFQSWAERLNVAPGRLNDAFISAMAEICSPLPGAVS
                     LLNAIRGQAKIGIITNGFTALQQTRLERTGLREYFDLLVISEQVGVAKPDPKIFNYAL
                     EQAGNPDRSRVLMVSDTAESDILGGINAGLSTCWLNAHHREQPAGIHPTWTVASLSEL
                     EQLLCKH"
     gene            complement(35611..36057)
                     /gene="rimI"
                     /locus_tag="OPY25_000673"
     CDS             complement(35611..36057)
                     /gene="rimI"
                     /locus_tag="OPY25_000673"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCS0926367.1"
                     /translation="MNTISILSTTDLPAAWQIEQRAHAFPWSEKTFFGNQGERYLNFK
                     LTADDRMAAFAITQVVLDEATLFNIAVDPDFQRRGLGRMLLEHLIDELEKRGVVTLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTAQGHEDAIIMALPISM"
     gene            complement(36002..36439)
                     /locus_tag="OPY25_000674"
     CDS             complement(36002..36439)
                     /locus_tag="OPY25_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HCS0926368.1"
                     /translation="MTSRRDWQLQQLGITQWALRRPGALQGEIAISLPAHVRLIVVAE
                     ELPALNEPLMRDILRALTVSPDQVLPLTPERVAMLPQGSRCNSWRLGTDAPLQLEGAQ
                     VTTPAFNELRVNPAARAALWQQICEHEHDFYPQHDRSPRSLAD"
     gene            36542..37570
                     /gene="rsmC"
                     /locus_tag="OPY25_000675"
     CDS             36542..37570
                     /gene="rsmC"
                     /locus_tag="OPY25_000675"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HCS0926369.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARFECAASRA
                     YTQQFHHWQALSRQMGDNVRFSLVAQASDVADCDTLIYYWPKNKPEAQFQLMNILSLM
                     PVGSDVFVVGENRSGVRSAEPMLADYAPLNKVDSARRCGLYHGRLEKQPQFSLESWWA
                     EYNIDGLTIKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSAALASHS
                     PKVRLTLCDVSAPAVEASRATLAANGLEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPKILDETFGFHEVIAQTGRFKVYRI
                     VMTRQAKK"
     gene            37761..37847
                     /locus_tag="OPY25_000676"
     tRNA            37761..37847
                     /locus_tag="OPY25_000676"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37795..37797,aa:Leu,seq:cag)
     gene            37875..37961
                     /locus_tag="OPY25_000677"
     tRNA            37875..37961
                     /locus_tag="OPY25_000677"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37909..37911,aa:Leu,seq:cag)
     gene            37993..38079
                     /locus_tag="OPY25_000678"
     tRNA            37993..38079
                     /locus_tag="OPY25_000678"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38027..38029,aa:Leu,seq:cag)
     gene            complement(38111..38347)
                     /locus_tag="OPY25_000679"
     CDS             complement(38111..38347)
                     /locus_tag="OPY25_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HCS0926370.1"
                     /translation="MLQRTLGSGWGVLLPGVIIVGLAFIGLSAYALKLLIVSGLLLSA
                     LMLYHKQLRHFVLLPSCIALIGGMMLAMMNWNQG"
     gene            38598..39662
                     /locus_tag="OPY25_000680"
     CDS             38598..39662
                     /locus_tag="OPY25_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCS0926371.1"
                     /translation="MTTPSWRSLRIKKYQFSLRLFLFLSAVSALFTLVFPLYQINVFC
                     TPMIGIVGLSVLLLIWHGKYGQKRINLPFISLLFGGIWAARIALKYPALGHYDFSFLL
                     ISLLSVLFIGSIAFAANIVAFTLYSLPPVAVCLWLNGNEQGLRILYLLALPMVGIAIQ
                     HVIQKRYDNFAQQLMFKLLAERETLNGLSMLDPLTGLYNRRGLQNRLDTLQAPGSHEH
                     YVLLLDIDHFKAYNDHYGHMMGDQALIRVSAAIRDAVRSRDVVCRFGGEEFLVLLTTA
                     EPQQARATAERIRQEVYDLKIPHMFNESVATNVTVSIGIAPLTDRNIGDAIEKADKAL
                     YEAKHLGRNHILVSDDMRAL"
     gene            39783..40571
                     /gene="fhuF"
                     /locus_tag="OPY25_000681"
     CDS             39783..40571
                     /gene="fhuF"
                     /locus_tag="OPY25_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HCS0926372.1"
                     /translation="MAYRSAPIADDIIWRAAPQPEDASLADAVRETIASTRQHLLDFI
                     RLDETPPPTAMTLAQWTRPATFRSLLAAYSDHIYRHTPGLPRENKPLLSLWAQWYIGL
                     MTPPLMLALLTQARAINVSAEHIHVEFHETGRAACFWLDVHQDNLATERSPEERMETL
                     IVSALQPVIQALEATGDINAKLIWSNTGYLINWYLTEMKPLLGEALLATLRQRCFFEK
                     QLSDGQDNPLWRTVVMRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            40722..41180
                     /locus_tag="OPY25_000682"
     CDS             40722..41180
                     /locus_tag="OPY25_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HCS0926373.1"
                     /translation="MSLQSVRQFLAAHAPDIEIIELNQSTATVELAAKAHNVEPGQIA
                     KTLSLKVKDTIILVVAKGDARLDNKKLKTTFGAKARMLSSDEVVNATGHPVGGVCPFG
                     LEHPLPVYCDISLKGYNEVLPAAGATHSAVRITPERMAELTSATWVDVCQ"
     gene            complement(41231..41905)
                     /gene="bglJ"
                     /locus_tag="OPY25_000683"
     CDS             complement(41231..41905)
                     /gene="bglJ"
                     /locus_tag="OPY25_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463407.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HCS0926374.1"
                     /translation="MENRISKRNVALVEKCVMSTIGIKGLFDAMPDCRHTLHIFSKPS
                     AFYKAALKTPFSAVIFSLSALRTERRTGLSSLTELAINYPHMRRLVIADDDAEARLIS
                     ALSPLPLDGVISKASPLDVLQDALFTSLNSARRTTERTDNLWELHQNCMLSPTEREIL
                     RFMSNGYSMPQIAVQLERNIKTIRAHKFNVMSKLGVSSDAGLLDAADILLYLRAGDAT
                     ALQHRV"
     gene            complement(41866..42591)
                     /locus_tag="OPY25_000684"
     CDS             complement(41866..42591)
                     /locus_tag="OPY25_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCS0926375.1"
                     /translation="MLPGCCKNGLIISKTPLIQEGLKGAITGNFPDYKLAYCRTIEEL
                     TLLQLRRSNLVIADLAVNNASPRAICEYFYSLISQYRDIHWVFLVPKSCYPHAVDLLM
                     GPVSTLLSDEEPIENLISVIHAGNARSERISKTLLSPQVPSEIQQSHDRPIVLTLSER
                     KVLRLLGKGWGINQIAALLKKSNKTISAQKNSAMRRLSIHSNAEMYAWINSSQGAREL
                     NLPSVYGETMEWKTESAREMLRS"
     gene            43304..44080
                     /locus_tag="OPY25_000685"
     CDS             43304..44080
                     /locus_tag="OPY25_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HCS0926376.1"
                     /translation="MQEEQSIQRAVTRLCIQCGLLLLQHGAESALVDELSTRLGLALG
                     IDSVESAISSNAIVLTTIKDGQCLTSTRKNQDRGINMHVVTEVQHIVILAEHRLLDYK
                     GVEKRFSQLRPLRYPRWLVAFMVGLSCSCFCKLNNGGWDGAVITFFASMIAMYIRQML
                     AQRHLHPQINFCITAFVATTISGLMLTLPAFSQTPTIAMAASVLLLVPGFPLINSVAD
                     MFKGHINTGLARWAIASLLTLATCVGVVMSMTIWGLRGWV"
     gene            44071..44544
                     /locus_tag="OPY25_000686"
     CDS             44071..44544
                     /locus_tag="OPY25_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HCS0926377.1"
                     /translation="MGIIDFLLALMQDMILSAIPAVGFAMVFNVPHRALPWCALLGAL
                     GHGLRMLMMSAGFNIEWSTFMASLLVGSIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISHLGYSEPMMITLLTNFLKASSIVGALSIGLSVPGLWLYRKRPRV"
     gene            44637..45176
                     /gene="dnaT"
                     /locus_tag="OPY25_000687"
     CDS             44637..45176
                     /gene="dnaT"
                     /locus_tag="OPY25_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HCS0926378.1"
                     /translation="MSSRILTSDVIGIDVLLHDHHAVLAKSTGGAVAVFANNAPAFYA
                     VTPARMAELLALEEKLSRPGSDVALDAQFYEEPEAAPVAIPCGKFAMYPAWQPDADFQ
                     RQAALWGVALREPVTAEELAAFIAYWQAEGKVFHHIQWQQKLARSVQISRSSNGGMPQ
                     RDINSVSEPDNHIPPGFRG"
     gene            45179..45916
                     /gene="dnaC"
                     /locus_tag="OPY25_000688"
     CDS             45179..45916
                     /gene="dnaC"
                     /locus_tag="OPY25_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HCS0926379.1"
                     /translation="MKNVGDLMQRLQKMMPAHITPAFKTGEELLAWQKEQGEIRAAAL
                     ARENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECDGQMNALSKARQYVDEFDGNIASF
                     VFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSNRETSEEQLLNDL
                     SNVDLLVIDEIGVQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKMLGERVM
                     DRMRLGNSLWVNFSWDSYRSRVTGKEY"
     gene            45974..46435
                     /locus_tag="OPY25_000689"
     CDS             45974..46435
                     /locus_tag="OPY25_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HCS0926380.1"
                     /translation="MNTAKHVLCCAAIASVLISTSGIAASQLSAQGANAQQGGMSLSA
                     LTGLLSRGAQSLSADNMNNAAGILQYCAKQKLASATNVENVKNQILNKLGLDTTQQEQ
                     DTNYLNGLQGLLKTKDGQQLNLNNIGSTPLAEKVKTKACDLVLQQGLNFLS"
     gene            46718..49009
                     /gene="opgB"
                     /locus_tag="OPY25_000690"
     CDS             46718..49009
                     /gene="opgB"
                     /locus_tag="OPY25_000690"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HCS0926381.1"
                     /translation="MSELLSVALFLASVLIYAWKAGRNTWWFAATLTVLGLFVILNIT
                     LYASDYFTGDGINDAVLYTLTNSLTGAGVGKYILPGIGIALALVAVFGALGWVLRRRR
                     HHPHHVGYSLLALLLALGSVDASPAFRQITELVKSQMRDGDPDFAVYYKEPAKTIPHP
                     KLNLVYIYGESLERTYFDNDAFPNLTPELGALKNEGLDFSHTMQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGAEELKTVVADPSYRNDWGFYDDTVLDEAWKKFEALSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKRYDYDGKPNQSFSTVSCSQENIAEFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFILRGDKPQQETLAVKRNTMDNGATVLDILGGDNF
                     IGLGRSSLSGQSLSEVFLNVKEKVLAMKPDIIRLWNFPKEIKDFTVDRDKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWIDRCYKMAQLWAPALA
                     LSTDWCVSQGQLGGQQTVQHVDKAQWQGKTAFKDTMIDMERYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKAPLPKKFDLVITA
                     KAFGDNANRPIPVRVGNEEQTLVLGHDVSTITLHFNNPTDANTLVIAPPAPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVNVES"
     gene            complement(49178..50838)
                     /gene="tsr"
                     /locus_tag="OPY25_000691"
                     /pseudo
     CDS             complement(49178..50838)
                     /gene="tsr"
                     /locus_tag="OPY25_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463392.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
     gene            51205..53355
                     /gene="btsT"
                     /locus_tag="OPY25_000692"
     CDS             51205..53355
                     /gene="btsT"
                     /locus_tag="OPY25_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HCS0926382.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLSVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGTV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFLRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVILNPELKMPALTQYVDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLACETDARFIGYGAMLMESFVAVMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPLIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFVPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLSTVVLIKMQRTKYIWVTVIPAVWLLICTTWALGLKLFSANP
                     QMEGFFYMANLYKEKIANGTNLTAQQIANMNHIVVNNYTNAGLSILFLVVVYSIIFYG
                     FTTWMKVRNSDKRTDKETPYVPVPEGGVKISSHH"
     gene            53450..53653
                     /locus_tag="OPY25_000693"
     CDS             53450..53653
                     /locus_tag="OPY25_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HCS0926383.1"
                     /translation="MFDTLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMTY
                     EEFFRERQQARYGGDGKGGMRCC"
     gene            53664..54620
                     /gene="yjiA"
                     /locus_tag="OPY25_000694"
     CDS             53664..54620
                     /gene="yjiA"
                     /locus_tag="OPY25_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HCS0926384.1"
                     /translation="MTPIAVTLLTGFLGAGKTTLLRHILNEQHGFKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCTRSNELEDALLDLLDSRDRGDIAFDRLVIECTGMA
                     DPGPIIQTFFYHDVLCERYLLDGVIALVDAVHANEQMNQFTIAQSQIGYADRILLTKT
                     DVAGDSEKLRERLARINARAPVYTVVHGDIDLSQLFNTSGFMLEENVLASQPRFHFIA
                     DKQNDVSSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDETPHSTLVFIGIQLPEDEIRAAFAGLRK"
     gene            complement(54695..54997)
                     /locus_tag="OPY25_000695"
     CDS             complement(54695..54997)
                     /locus_tag="OPY25_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HCS0926385.1"
                     /translation="MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDG
                     QWSEAVRGKFFRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLREQNKK"
     gene            complement(54984..55271)
                     /locus_tag="OPY25_000696"
     CDS             complement(54984..55271)
                     /locus_tag="OPY25_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HCS0926386.1"
                     /translation="MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYEN
                     GEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIISARKADRKERNRYEHG"
BASE COUNT        12943 a        15265 c        14196 g        12880 t
ORIGIN      
        1 tattatcaaa aaagagatct tgctctataa atccagtcat ctaccgtact tctttagtgg
       61 tattttatta aactttgtta ccgggtccga aactggactg ccgttcaata ttgcatcaga
      121 atttttattg agttcatagt tgatatacgt agaatagccg cctgcttatc tacagaacag
      181 aaagaagcgc atacagagta aaatataata ttttatttta tatagctatc tttatttttc
      241 agcgaataga atcaggcaac aattaatatg tttaataaga aaattatcat cctggcaatg
      301 ttaactgccg tagcatccac accggtattt gcccagaaca cgattacgtt caatggcaaa
      361 atttacgatc aggcgtgtac ggttcaggtt aatggctcca cggataccac cattgattta
      421 ggtaattaca gcaaagaacg catcgcggaa aaaggcgcca caaccgatta cgtgccgttt
      481 accgtaagcc tggttagctg cccggaagca gggactggcg taccgaccca ggccatgttc
      541 cgcttccacg gcgcaacaga tgattccaac ccaacgtact tcaaaaacgc ggacgaagga
      601 tcggaaacgg gcgccgcggg tgtcggtatt tctattcaga acgcttcaca tagcgatgtg
      661 acagataaca cggatgatgc cgcagtaagc ctgccaaccg acggctcgac agcagacttt
      721 acctattacg ccgccatggc aaacgatggt tccgcaaccg taaccggtgg agatgttagc
      781 actcaggtta cgtataccgt ttcgtatcag taaggcattc tcatcctgat gtggacaggc
      841 aggatgccag tccatagcgt aaaacatctt tacagagtaa aaaatgaaac acataaagaa
      901 atccgtgttg gtcgtattac tgacaagcca tgttgcccat gccagcattg ttgttggcgg
      961 aacccgactg gttttcgacg gcaataatga tgagtcgtca atcaatgtag agaataaaga
     1021 cagcaaagcg aatcttgttc agtcatggtt atcggttgcc gatccccagg tcacaaataa
     1081 gcaggtgttt attatcaccc cgcctctttt tcgccttgat gccgggcaaa agaacagtat
     1141 tcgggttatt cgctctggcg cccctctacc tgcagatcgg gagtctatgt actggctcaa
     1201 tattaagggt attccttcta ttgatgataa tgcctccgcg aaccgcgtgg aaatctccat
     1261 taatacccaa ataaagctta tttatcgacc gccagcatta accaaatcaa cgcctgatag
     1321 ccagagccaa caattaaaat ggcagacggc aggggatgtt attaccgtaa ataaccctac
     1381 cccctattat atgaactttg ccagtgtgac gcttaacagc catgaagtga aatcagcgac
     1441 cttcgttccg ccaaaatcat cagcgtcatt taaattgagt tcgactgccg cccctcatgg
     1501 tacggtaacg tggcgattaa tcagcgatta tgggatgagt ttagagccgc attccggttc
     1561 attctagcca ttaacgactt cactttactt ttaccctttc aggactttta ctgtgcaatt
     1621 ctccagagta gagccccgtt ctcaattagc gttatcgttt ctctttatat gctgatccat
     1681 aaaaccagcg ttagcgcatg atcattttaa tccattatcg ttggaaaatg atgaaccggg
     1741 cgtggagaat gtcgatctat cggttttcga aaaggggggc aggcagaagg cacctataat
     1801 gttgatattt atattaataa cactaatgtt gaaacaaaaa atattgcctt taaaaataaa
     1861 aaatcagcag ataataagct ctccctacag ccatgtctta gcgttgaaca actcaagcag
     1921 tggggcgtaa aaacagaaaa cttccccgag cttaaaaatg acccaaacgg gtgtaccgat
     1981 cttagtctgc tggctggcgc tgtagcaaag tttaatgtca tcggtaaccg gctggattta
     2041 gcgatccctc aaatcgcgtt gatcgccgac ccgcgagaat tcgtccctac cagcaaatgg
     2101 gatgaaggca ttaatgcttt tttgctgaac tacagtttta ccggatcgca ggatcacgat
     2161 attgatgaaa accggacgga aaatagcgaa tacgctaacc tgcgccctgg tattaacatt
     2221 ggcgcatggc gttttcgtaa ctactcaacc tggaatcatg atagcgatgg gcaaaatagc
     2281 tgggattctg cctacaccta tgtttctcgc gatatcgaat ttttaaaagg acagctgatc
     2341 gccggggaaa ataacacgcc cgcagacgtc tttgacagta tttcatttaa gggcgtacag
     2401 atctcttctg atgacgatat gttgccggac agtatgaaag ggttcgcccc ggtcattcgc
     2461 ggggtggcca aaagcagcgc gcaggtaacc gttgaacaaa acggttatac catctacaaa
     2521 actaacgttc cggcgggccc attcgccatc aacgatcttt atccaaccgg cggttcgggc
     2581 gacctgtacg tcaccatcaa agaatccgat ggttctgaac agcatttcat tgtgccctac
     2641 gccagcgttc cggtattaca gcgtgaaggc cacctgaaat acgacttgac ggtaggccgc
     2701 acgcgttcat cagatacgca ttccgcgcaa cagaatttcg cagaactgac ggccttatac
     2761 ggattagcag gcggcgtaac cgcctatggc ggaatagaga gtacgctgag caatgatgtt
     2821 tatcatgcgg cgctcatcgg gacaggctta aaccttggcg atctgggcgc attgtcttta
     2881 gacgtcacca actcatggtc aaaaattaaa gcaggcgatg tggttagcga tacgcttacc
     2941 ggacagtcct ggcgtattcg ttacagcaaa gatattcagt caacaggcac caattttact
     3001 gtcgccggtt accgttattc gaccaaagat tactacgctc ttgaggatgt gctggatacc
     3061 tatagcgata atagtcacta tgatcatgtc cgcaatcgca ccgacctgtc gttgtcgcaa
     3121 gacattatct acggttccat ttcactcact ttatataatg aagattactg gaatgacact
     3181 cataccacat cattaggtat tggctataac aacacatggc ataacgtaag ctatggcatt
     3241 aactattctt atacgctgaa cgccgataat actcaggatg aagacgacga tacggaagac
     3301 agtaatgacc agcaaatttc aatcaatatt agtattccgt tagatgcctt tatgccgtca
     3361 acgtatgcca cctacaatat gaactccgcg aaagacggcg atatcacgca tactgtcggt
     3421 ttaaacggca cagcgctggc acagaaaaat ctctcatgga gcgttcagga aggttattcc
     3481 tctcaagaga aagccaccag cggtaatgtg agcgcaacct ataacgggac gtatgcggat
     3541 attaacggcg ggtatagcta cgataatcat atgcgtcgcc tgaattatgg cgttcagggc
     3601 ggcgtactgc tacatcgaaa tggcctgaca ctatcccagc caatggacga caccatcata
     3661 ttggttaaag cccctggcgc agcaggtgtc cccgtgaata acgaaacggg cgtggacacc
     3721 gattttcggg gttatgccgt cgtacctaat gcttcgcctt atcatcgtaa tgaagtgtct
     3781 ttagatacga caggcattag aaaaaatatt gagctcattg ataccagtaa aacgctggtg
     3841 cctacccgtg gcgcggtggt cagggctgaa tataaaacca atattggcta caaggcattg
     3901 atggtattaa cccgcataaa caatctgcct gttccttttg gcgcgaccgt ctcgtcttta
     3961 acaaaaccag acaatcacag cagttttgtt ggtgatgcgg ggcaagcctg gttaaccgga
     4021 ctggaaaaac aagggcggtt attagtgaag tgggggccaa cagcagcaga ccggtgtcag
     4081 gtctcttatc gtataccgag ctccccctcc gcttctggcg tagaaatctt acacgagcaa
     4141 tgccagtgat tctggtggga taaaagatga atatgaacag atttgctgca ttagccgccc
     4201 tgttaacgtt cacgggtctg gcatcatggt cgccctcgat cagcgcggca tacaataccg
     4261 cagatgccgt agacattaac gttacgggat taatttatgc cgatccgtgt accgtgacgg
     4321 tacctgacac gatctctctt gggcaatatg cccgggcgga tatcgctgtg gccggtggca
     4381 ataccgccac cattcctttc accataaaaa tgacgaattg cccggcaacg accacaaaag
     4441 ccgcgatttc atttaacggc gtaccttatc ccgatccgaa ttatgcttct gcgatttacg
     4501 caaacagcgc ggccaatccg gcgcaggatt taggattaca gctttttaac ctggacagta
     4561 aaagtctggt taatctggcc aataacgtca cttacacggt ggatatcaac agtaataccc
     4621 atgaagccaa tttgcctgtc gccgcaagga tgtatacccc gtatggaaaa gtcacggcag
     4681 gggatttcac gtccgttgtg acgatcacta tcgcatggca ataatatttt tctatttcac
     4741 ctgatataaa agcaggaatt tttcatgaga aggttatatc tggcgcttat tctgctgttc
     4801 gcgtattccg gtcatagtta cgcctcctgt aaacgttccg gtaatgaagg cgcgatcact
     4861 atcaccccgc cgtcgcagct tgtggtggat agccacgcct ataccgcagg cgaagtgttg
     4921 tggcaatcgg gctgggtttc cacctccgaa gtcacaatgg atggctgtag tcgcgattat
     4981 aaggtcggtt tttatatgaa cccggtagcg cgcagtcaaa tacatccgcg acaatcaatg
     5041 cgaatgacgg gaacaacacg ccggtattta gcaccgggat ttccggcgtg ggcattgcga
     5101 ttaaaaccca aacgaatgct ggcccttacg ataatgtcat gccaatcgat aatacgtacc
     5161 ataatggcga tggcaataaa acccaccatg cgatggcccc cgcctacaat gttgaactgg
     5221 tcgccttagg cggtccgatc acctccggta ccgcgacatt ccaaagccca ctggcacgtg
     5281 tatcctttcg cgatagcgca acggaaagct ctggcggcga tatcctgacc catctgtatt
     5341 tgggtaatac gcaattgatc atgaaagcga tgggatgtcg ggtagaaaca cctgccatca
     5401 ccgttgattt aggcagcgtc aatttaggca gtttcgctaa cagtcaaacc gcgggcacag
     5461 gcaagcagga tatcttattg acctgcgaac aaggcaccgc tatctccgca tcgttaagcg
     5521 cccaaccggc cagcggaaat aaccctgata attcagtcat ccagttgagc aatgcaagcg
     5581 cgccaaccag cgcaaccggc gttggcgtac agttgggtat tcaggcgccg gactctggtt
     5641 tctttaccga cagtttgcca atcaatcaaa aaattgatct ctttactcac acgattacca
     5701 ccaatgccga tggcagccag acggttaacg gcggaaccat gaatatgtcg accaccctga
     5761 aaattagcgc gcgctactat aaaaccgccg ccacggtaac ggccgggcaa gcgaatgcca
     5821 cggcaacatt aaacctgacc tataactgac ggcatcacat tttctggcgc tgcgcgggaa
     5881 aacgttaacg cgcgcgcccg ttagatttat ttccacaaac gtaattcgtc atcttttact
     5941 ggcggtaatg acttacgttg ctgacaagag agcgaatacc agtccagatg gcgcgtcagg
     6001 aacatcacgc cgccaagcgc cagtagcaga acgccggtac ccagaagcaa cgagctatct
     6061 tccgaacgca gtaaccccca catcacgcca tccagcgcca ataacgctaa cgtaaacagc
     6121 acgctattgc gccatccttt cagtaccgcc tgcaaataaa cgctattcat caacgcgccc
     6181 actaggcttg cggcgatcca ggctggcgtg aaaccgatat gttccgacag tgccagcaac
     6241 agcaggtaga acatcaccag cgataaccct accagcagat actgcatcgg gtgtaatcgc
     6301 tgtcccgtca gggtttcgaa gacaaagaaa gccataaacg ttagcgtaat caacaaaatg
     6361 gcatatttcg tcgctctgtc cgtcagttga tactgatcgg ctggcgtcga tacagcgacg
     6421 ctaaacgccg gtaagttgtc ccaatccacc ttttgcgcat cagcaaactg ttcgccgaga
     6481 ttcgtggcaa accggctggt ttgccactga gcctgaaatc ctgaaccgct gatttcgcgt
     6541 ttaccgggaa gaaaatcccc cacaaaattt gggtgcggcc agttactggt cagggtcatt
     6601 tcactgctac gcccgacagg aaccagtgaa aagctgccgg ttccgcttaa atttaacgac
     6661 atcgccaacg tcaggttgcg cgtcgcccac tgactgtccg gtagcgggat atgaatgccc
     6721 tctctacttt ccggtaagcc ggtccccggt tctacagtga gcatttcacc attcacctgc
     6781 ggcgctttta ctgcgctgat accgcgcgca tcgccgacgc ccacgacgat aaagggcttt
     6841 ccaagggtaa tattcggtct gttcagctca tgcagacggg ccacatcaaa ctctgccttt
     6901 atcgccatat cggtatgcca cacctgcccc tgataaatac ctatttttcg cgcttcaacg
     6961 ttttgattgc cttcgaccaa tagcgactcc ggcagccaaa aatagagata gctgcgctta
     7021 tactgaacct ctttctcctc ttccagcacg gtatagagct ctgtcaccgg aaccgccacc
     7081 agcgggccga caaccttttg cgggccgctg gtactctgac gaatagcggc ttctacatgg
     7141 cttcgataat cagcacgctc cacgatggtg tgccgtacca tcatcagggg aattaacagc
     7201 aggatcatgg cgccgcctaa cgtaatcatt ttccacaaca ggggggattt caacatagcg
     7261 ttctcctttg caatgccagc agtgtaagaa cgcgatgtgg ggagaatttg aagttatgtg
     7321 aagtgacggt gaagtgtcaa cgaggccagc acgccgcctt cgggacggtt gcacaacgtc
     7381 acctcaccgt tgaggagccg cgccgcctcg ctgacaaacg ccagcccaag cccgctgctt
     7441 ttacgcccgt tttcacgggg caacgaatag aatcggtcga aaatgcgcgg cagcgcaaaa
     7501 tcaggaatac cacagccgga atccgtcacc tgcaggatcg ctttctctcc catcggctga
     7561 gcgcttaatg tgataacgcc attttcaggc gtaaagtcga tggcattgtc caacacattg
     7621 cccagcgcct gcgccagaag ctccgcgtcg gcgacgacaa ccagcgagga aggacgtaga
     7681 gtaagcgtga tcttttttgc cgccaactga atactgcgcg cctcgctaag ctgcgtaaat
     7741 agctcatcaa cagcaaccgg cgcgagaggg atatcctgtc ggttttccag ccgcgcctgg
     7801 cgcagcaggg tttctaccag cgcctgcatt cgcgtatttt gcgccagtat attctctgta
     7861 aagcgggtaa ccacatccgc gggcggtcct tcacgcagaa tctccgccgc gccgcgtatc
     7921 gccgccagcg gacttttcag ctcatgagtc aacgcataca cgtactgctc aatgtcattc
     7981 ttgccttcca gcttaatgcg catactctcc agcgcctgcg ccagtttacg cagctcgctg
     8041 ctgcctaatg caggtaacgc aagcgggcgg ttttcggtga cggaatccgc atagcgcgtc
     8101 aaccgggcga tggagcggtt aatccaccag accatccccg cgccaatcgc cagcgcaatt
     8161 cccagtaaaa cggcgctggc ccacagaatg cgccgttcgc tgcgcttaat caccggcgcc
     8221 attgccgcat tcggtttgcc gacagtcagg acgccgatga tccgtccatc gctgattatc
     8281 ggcgcggcta cgtacatcac ggtgctattg ggatcggcag aatcttttgc cgtgctgcgg
     8341 gcgccatact gtccgcgcaa cgtaagccag acgtcattcc agcgagaata atcctgcccc
     8401 accgctttgt tttccgaatc aaacaacacc ttcccctgcg catccgtcat gtagacatgg
     8461 tattcattac gcactttgac gatcccgctg atattggcgc gaaacgggcg atgttgcagc
     8521 tgggcgaatg ctttcgccaa ctggccgtca gtcgggttgc cggaaaggag atcgtcgcgg
     8581 gccagcgccg ccagcagcgt cgcggtgtca atcagcgtcc cttccgtcgc gcggcggacg
     8641 cccggcttta tctcctgaac aaagatagac agcacaaaca cggcggcgac ggcgacaata
     8701 agaaagtagc ccagcagcaa acgcattccg atgcgcatca gatgctcctc aggctgtatc
     8761 ccattccacg atgcgtgtta attggcgaga gatccgggtt gatcgcgcgt agtttagcgc
     8821 gcagggtttt gatgtgcgta tcgaccgtcc gatcgaaggt ctcttgggca tcagaccaga
     8881 caatatccat caattgctgg cacgagtaca cgcgctccgg cgacagcagc agggttttaa
     8941 ggagcagaaa ctcataacgc gtcagcgaga gcggcgtacc aaaccaggcg atctgcgccg
     9001 ccggttcatt gagatcaaaa tgtccggtac gcaccaccgg cgacggcgca gcaaactttt
     9061 tcacccggcg cagcagcgtg cgcacgcggg cgctcacttc gcgcggcgag aacggcttgg
     9121 cgacataatc atctgcgccg atctccagac caagcaatcg atccacttca tcgctacggg
     9181 cagtcaggaa aagaatcggc agcgccggat gacgctccag caactgccga cacagctcaa
     9241 agccgctgat atccggtagt cccacatcga gaatcaccgc atctggccgt tgctgacgcg
     9301 ctttttccag cgcgggcagc ccgcgagcga atagctcaac ggtaaaccct tccagttgca
     9361 gggtgtagat gagcgtatcg gcgattccct gttcatcctc gactaaccag acctgcggtt
     9421 gctgcatacg ctttccctgt tattgtcgcc acggcatgac cggcaccgcg ctgatggcgt
     9481 tcttcggcga cccgtcgacc actttgtcgg agtaggccag atacgccagc gtgttgcgtt
     9541 tctcatcata gaaacgtacg gcctgtaatg acttaaatat caatgaggtg cgttttttga
     9601 aaaccacctc tccctgcgcc ttgccgttct taattttgtc gctcagttca ataggcccga
     9661 cctgctgaca agagatagcg gcgtcagacg tatcttccgc cagccccaat ccgcctttta
     9721 tgccgcccgt tttcgcccgg ctaacatagc acgtcacgtt tttgacatca ggatcgtcaa
     9781 aagcttccac cacgatttta tggtcagggc cgaacatttt aaataccgta tcgactgaac
     9841 caatttgttc cgcgcgggcg ctctgcccca gcagcaacaa aattgagaaa agtactaagc
     9901 tcttgtattt catattgtta ccattcataa aagctacgtt gcgtaattat tagacattct
     9961 aaaataaaat ggttatagat cacaggatta gaataattac ctgtcacgtt gcctaaaaaa
    10021 agcatttaag ctcaaaaaaa acactgaatg ctaaaagaac aaaaaatgct attatcctct
    10081 tacctgatat cgggtgctcg ttgttgaaag gatggggata ttttatggat caggctggca
    10141 taattcgcga cctgttaatc tggctggaag gtcatctgga tcagccgctg tcacttgaca
    10201 atgtggcggc aaaagcaggc tattccaagt ggcacctaca gagaatgttt aaggacgtga
    10261 cgggccacgc tattggcgct tatatccgcg cccgtcgttt atcgaaatca gcagtggcgc
    10321 tgcgtttaac cgcgcgtcca attctggata ttgctcttca gtaccgcttc gattctcagc
    10381 aaacctttac gcgcgccttt aagaaacagt tttcccagac gccagcgttg tatcgtcgct
    10441 ccccggaatg gagcgccttt ggcattcgcc cgccattacg gctgggcgag tttaccgtgc
    10501 cggaacatca gttcgttacg ctggaagata cgccgctgct tggcgtcacg cagagctatt
    10561 cctgctcgct ggaacagatt tccgacttcc gccacgaaat gcgcgtgcaa ttctggcatg
    10621 atttcctcgg tcattcgcca actattccac cagtgcttta tgggcttaat gaaacgcgcc
    10681 ccagcatgga gaaagacgat gagcaggaag tattctatac caccgcactg ccgcaagagc
    10741 aggccgatgg ctatgttcag tcggcgcatc ccgtgctgtt gcagggaggt gaatacgtca
    10801 tgttcaccta tgaagggtta ggaaccggcg tgcaggattt tatcctgacc gtttacggca
    10861 cctgtatgcc aatgctgaat ctgacccgtc gtaaagggca ggatatagag cgatactacc
    10921 cgtcagaaga taccaaaacc ggcgatcgcc ctatcaacct gcgctgcgaa tttctgatcc
    10981 cgattcgccg ttaacgctgt agctcatcca atgcaggggt gtccagatgc gaaacgtccc
    11041 ctgcggtttc taccacccag ccagacgcca gccactgact ttcctggtaa tcgatacggg
    11101 aaatagagca gttgcgcaaa cgtaaccggc gttccgccca ggcgggtagt cccaggatag
    11161 tactgaccag acagcccaac gcgataccgt gactgaccaa taaaggtcgg ctgccctgcg
    11221 gtagctccag acaggacgcc agcgcggcat gaacgcgatc gctcaactcc tgcatcgatt
    11281 ccccaccagg aatgcggcca tcctgcgtgc cgttgaccag ctgacgacgc cagccctctt
    11341 cttcttccgt cagcgaatcg atctggcgct tttccagcac gcccatatcc agctcgcgca
    11401 ggcggaagtc aaaggtaata tcacacccgc acgcctgggc gataatctcc gccgtgcgtt
    11461 ttgtgcggcc taaatcgctg ctgatgatat gggtgatgcc gaggctgcgg gcgcgttctc
    11521 ctacctgcat ggcctgctgc tctccttttg ccgtcagggg actgtccgat tggccctgaa
    11581 tacgtcgctc ggcgttccac tgcgtttcac cgtggcgaac aaggtatacc tgtaacatgt
    11641 ttttttccgt tatactgcga taaattttta aaactgagct taattatgca ccaggttatc
    11701 tctgcgacca ccaatcctgc caaaattcag gcaattctac aggcatttga agagattttc
    11761 ggcgaaggat cgtgccatat tacacccgtc gccgtcgaga gcggcgtacc ggagcagccc
    11821 ttcggaagcg aggaaacgcg tgctggcgca cgaaatcgcg tgggtaatgc gcgacgcctg
    11881 catccacaag ctgatttctg gattggtcgc aaagagggcg ccattggcgt atttaccgcc
    11941 ggaaaattaa cgcgctccag cgtttactac caggcggtga tcctggcgct cagcccgttt
    12001 cataacgcgg tgtatcgata attatttgcg ctatgttgta ggcctgataa gcacagcgcc
    12061 atcaggcatt tcgcggcgat gttgccggat ggccgcttcg tcttatccgg cctacgagca
    12121 aatcaggcgc ttttcagcag tatctgctca agccaatgac gcagttcaac cggcgcggat
    12181 ttcaggctgt ttgacccgcg tgtgatggta gcgatgcccg cccccagctc ggttttcaac
    12241 tcgcgctggc tcatttcgcc acgcagcaac tcctcaataa tgcgcacgcg cgttcccagc
    12301 gcttcacgct cgtccggcgt aagcatcagt tgtaataaag gcagatgcag atcctctgca
    12361 tatgcctgac ggagtaactc cacaaaacga agccactcct gattacgttg ttcggcgata
    12421 gccgatgaat aaggggaatg ctgggtcatg ttataccgcc gtttgtactg ttacacgagt
    12481 acaaatgata acataacccg tctgcattaa taccgtcgct gccactcaga gtcgctcatt
    12541 aaggcctctt tctgtcccat aaagtggcga tagtaagcgt cataggccag aacgtttttc
    12601 acgtagccgc gcgtttccga aaagggaatg ctttcgacaa acgctacggc atcgatacgc
    12661 ccggcgctat tgccaagcca ggtgcgcacg cgtcccggcc cggcgttata cgccgccgat
    12721 gcaaaaatgc ggttattacc aaactgctga tagacatact gcaaatagct ggtgccaatg
    12781 ttgatgttgg tctccggctc cagcagttgg ccggggccgc ggtagtccgg aatcgaaaac
    12841 attttcaccg tatgggtggc cgttcccggc ataatctgca ttaaaccgct ggcccctacc
    12901 ggtgatttta ctttcgggtt ccaggcgctc tcctggcggg caatcgccat ggcatagctt
    12961 tgtgagatat cttttccgcg ggtatagcgg gtaaaaagat cgttatacgc cagcgggaaa
    13021 cgctcctcca gatgatccca cagttttccg gcgatcgtcg cctgtacgct cagatcccac
    13081 cagtgctggt taaacgcata gcgcgccagc tgcgcctgtt cagatttact acggcttttt
    13141 accagattcg cccattcgct gcgcgccgtg ttatccaggt tccagtacat cagctcccgt
    13201 acacgcgcca tctccggccc ctgcgtcaac gcgctgttta cgttggcggg cgctttatcg
    13261 attttaagcg tgtactcttc gcctaaacgc tgcgccgcga ccatcggata aaaaccgcgc
    13321 ttctgcatta aagcatgaag gatctctttc gcttcggcgt cacgaccgcg ctccagcaat
    13381 aaatccgcct gccagtaacg ccactcgtct ttctctttcg cctccatcgg caggcgggca
    13441 agccaggtat tgagaccgcg acgatcgccc atccccagcg ccatacgcac gcgccgctcg
    13501 ataagcgacg tcgattgcga gcgcataatc gcgtcatcgc gccatttcgc ctgcgcatcg
    13561 gtcacatcgt tgcccatcag tcgccaggca acgatatcgc gcagcgcctg cgtttgttcc
    13621 tcattaagtt tctgcgcctg taccagcgag gggatcatca gacgcgcatt ttccgcgtcc
    13681 tggcgggcga cgctggcaaa cgcgacttcc gccatctggc gggtaaaatc ggtggcgccg
    13741 gtggtgcgtg caaaggtcaa cacgttatta gggtcattag cgagggtaat gatcgctgag
    13801 gcgatcgttt gatattccgc cggcatctgt ccggccagca ccgtaaccag ccccgtattt
    13861 ccggctttca tcgccagccg aatacgttcc agatacgcca gcgggtcttg cttgccggag
    13921 gcccgccaga cgctgaacag tttatcgcag gcattcggct gacttttgcc ggtcagccaa
    13981 aggtctttcg cgccctgcca ggccgcttcc gtttgcccgg tactccattt cgcgtagtaa
    14041 tagttacatt gcgcttccgt ggtgccgggt ttctccgggc taaacgccag caagccgcgc
    14101 cagtcttcac gacgcgccag ctcattgacg aagcgcgatt gcagcgtacg cgcaggcgga
    14161 agcgtaggat tggcgcgcac aaactgcgtg acggcaatcg ccggttggtt catcaaatcg
    14221 tcggtgatct tacggtattc cagatacggg tagagcggat aatctttcag acccggcatc
    14281 atctgctcta ccacatccat ctggcggttg tcccaggcct gcttaatctg cgcatagcgg
    14341 ttacgctgct cttccagtga gtcggcccgc gcgaggtgac aaaaggtcaa caggcatacg
    14401 ctggcggcga cgagacgcca gacaaatggt ttggctctat ccacaagcac ttcctcaatt
    14461 gttatccaat gcagcatcat gccgcgtaat gaatttatgc taaccagtca tagccatttg
    14521 cgccacgtta cggacacttt tttactttta ttgcgagtgc gatctgctgg ctgggcttag
    14581 gcagggaaaa aggctacact tcgcctttga aatctattca ccatcacgat aaacatagag
    14641 gcgaagtcca acgtggctca attcgtttat accatgcatc gtgtcggcaa agtggttccg
    14701 ccgaaacgtc atattctgaa aaacatctcg ctgagcttct tccctggcgc caaaatcggc
    14761 gtgctgggcc ttaacggcgc cggtaagtct accctgctgc gcatcatggc gggtctcgat
    14821 aaagatatcg agggcgaagc gcgcccgcag cccggcatta agattggcta cctgccgcag
    14881 gaacctcagc taaacccgga acacacggta cgcgagtcga ttgaagaggc cgtttcggaa
    14941 gtggttaacg ccctcaaacg tctggatgaa gtgtacgcgc tgtacgccga tccggatgcc
    15001 gacttcgaca agctggccgc agagcagggc cggcttgaag agattatcca ggcgcacgac
    15061 ggtcataacc tgaacgtgca gcttgagcgt gctgctgacg ccctgcgtct gccggactgg
    15121 gatgccaaag tcgaaaaact gtccggcggc gagcgccgcc gcgtggcgct gtgccgtctg
    15181 ttgctggaaa agccggacat gctgctgctc gacgaaccca ccaaccacct ggatgccgaa
    15241 tctgttgcgt ggctggaacg tttcctgcac gacttcgaag gcaccgtcgt ggcgattacc
    15301 cacgaccgtt acttcctcga taacgtcgcc ggctggattc tggagcttga ccgcggcgaa
    15361 ggtattccgt gggaaggcaa ctactcctcc tggctggagc agaaagatca gcgtctggcg
    15421 caggaagcgt ctgccgaagc ggcgcgccgt aaatccattg agaaagagct ggagtgggtg
    15481 cgtcagggcg cgaaaggccg tcagtcgaaa ggtaaggcgc gtctggctcg ctttgaagaa
    15541 ctgaacagcg ttgagtatca gaaacgtaac gaaaccaacg aactgtttat tccaccagga
    15601 ccgcgtctgg gcgacaaagt cattgaagtc agcaacctgc gtaaatccta cggcgaccgc
    15661 gtactgatcg acgacctgag cttctcggta ccgaaaggcg ctatcgtcgg gatcatcggg
    15721 ccaaacggcg tgggtaaatc gaccctgttc cgcatgatgt ccggtcagga gcagcctgat
    15781 agcggcacca ttacgctggg tgaaaccgtc aagctggcct cggtcgatca gttccgcgac
    15841 gcgatggaca acagcaaaac cgtctgggaa gaggtgtccg gcgggctgga tatcatgaag
    15901 atcggcaaca ccgaaatgcc aagccgcgcc tatgtaggcc gctttaactt caaaggcgtc
    15961 gatcagggca aacgcgttgg cgaattgtcc ggcggtgagc gtggtcgttt gcatctggcg
    16021 aagctgctgc aggtgggcgg caacgtcctg ctgctcgacg aaccgacgaa cgacctggat
    16081 atcgaaaccc tgcgcgcgct ggaaaacgcc ctgctggagt tccctggctg cgcgatggtt
    16141 atctcgcacg accgttggtt ccttgaccgt atcgccaccc acattctgga ttatcaggat
    16201 gaaggtaagg tggaattctt cgaaggtaac tttaccgaat acgaagagta caagaaacgc
    16261 actctgggcg ccgaggcgct ggagccgaag cgtatcaagt acaagcgtat tgccaaataa
    16321 acgtctgaat gccgggtggc gcttgcgctt acccggccta caaacccagc gattccaata
    16381 cgttgtgaaa ctgtaggcct gataagacgc ggtaagcgtc gcatcaggca ttggttctta
    16441 tccctgctcg cccatcatct ctttcaccag ttccacacag cgcaaaaagc ggccatcgta
    16501 atcagcctct ttaacgtgaa cgaactcaat gttgttttct ttcagcatct cgaccagcag
    16561 gttctggaac gctttgcgat ccactgaact gcccaggctt cgcagtccgt cagctatcca
    16621 cggcgtatta ttctccagca aaatcaccag gtcgaagcga tactcgtcga tcagcgcctg
    16681 gacaaacgga tgctcgcgcc cttcgtattt tttgcaaaat gcctgggtgg tgacgaaatc
    16741 ggtatcgata aacgctactt tattcgcata tttcactgca aaatcaatat attgcgcatg
    16801 acccagcgca attttatcgt agtcggaata ctgtaacgcc atctcatcgc cgcccagatg
    16861 cgaaaagaca tagtcgcggc catattccca ggcgctggtg gtattaaaaa tattggcgag
    16921 cttattgacc agcgtagact tgccgcttga ttccccgccc agaatcgcga cggtacgcac
    16981 gaaaaacggc ttcacttcgg taggaatata ttcccagtaa cgaaacggat tttcgcggat
    17041 ttgcgccccg ctgatattca taaacgtgcg ttcaggatcg accagcaccg tctcaatccc
    17101 taaatgctcc aggtactgcg gcgcatcagc ctcttcggaa gtgtagatcc agctcggctg
    17161 tattcccttc tctgccataa acgctttaat gccgttgctc cagacgtccc agccatgcgg
    17221 ataaggttcc atcccctctt cattaaaggc gtggatgcga atattttttt ggtatttgaa
    17281 ggtttgcagc aaccagcgca ggcgatccga cacggtgggc tgctgcgaca tggcgctatc
    17341 ttcaaacagc ccgcggtcgc gcgtatcgtc atatcccata atgatgtgca actcatccac
    17401 ctggctacag gcacgctgga tcaagtagat gtgcccggta tgcaatggat aaaatttacc
    17461 gaacaccacg ccaatgtttt tctgtcggcg gggaaactcc agcccgagaa aacggtgtag
    17521 cgcctccagt ttttgcgcgc tggggctttt gattttggcg ttaagtaact gactcagata
    17581 ccccttggtc ataccgctgg cgtcagccac ctgttgcaga gtgcaacctt gctgcttaat
    17641 cgcggttttg agatagtcga acgatgacac aagagcctcc tgctggaaaa atcgcataac
    17701 actgcctgac ggcgcttcgc ttatcaggcc tacaacatca atccgtatca atccgtaggc
    17761 cggataagac gcattgcgtc gccatccggc aaattataca acatcactac atacagagaa
    17821 ttataagtcg tcaaacacgc ttaacgcatc tgcgagcttt ttaacaccga acacctgcat
    17881 tccttccggc ggctttttcg gtacgttggc ggcaggcaca atcgcccgac gaaaaccgtg
    17941 tttcgccgcc tcggaaatac gctcctgccc gctcggcacc ggacgaatct cgcctgccag
    18001 ccccacttcg ccaaacacca ccagatcctg cggcaacggc ctgtcacgca ggctggagac
    18061 catcgccagc agtaaagcca gatccgcgct ggtttcggtg actttcacgc cgccgaccac
    18121 gttgacgaag acgtcctgat ccgacatttg cagaccgccg tgtcggtgca gcaccgccag
    18181 caggatagcc agacggtttt gttccagacc gaccgccacg cgtctggggt tcgccatcat
    18241 cgagtgatcg accagtgcct gaatctccac cagcaacggt cgcgtacctt cccagacgac
    18301 catcactgag ctgccggaag tgacctcatc gccgcggctt aaaaagatgg cggacggatt
    18361 gctcacttcg cgcaacccct gttcggtcat agcgaagacg cccagctcat tgactgcgcc
    18421 aaagcggttt ttgtggctgc gcagcgtgcg gaaacgagaa tcggcgtcgc cgtcgagcaa
    18481 tactgagcaa tcaatacagt gttccagcac tttcggcccc gccagcgacc cgtctttggt
    18541 gacgtggccg accatcacga tcgccacgcc gcgcgtttta gcgaagcgcg tcaggtaggc
    18601 tgccgtttcg cggacctggg cgacgctgcc cggcgacgac tggatgtccg ccatatgcat
    18661 cacctgtatg gagtcgatca ccattagctt cggctgttct tcttccgcta tcaggcagat
    18721 ctgctcgatg ctggtttcgg agagcatatt cagattagcg gtcggcaggc cgagacggtg
    18781 cgcgcgcatc gccacctgct gtagcgactc ttcgccggtg acgtacagcg ttttcatctg
    18841 ctcggcaagt ttgcacagcg tttgcagcag caacgttgat ttgcccgcgc cggggttacc
    18901 gccaatcaaa atggcgctgc cgggtaccac cccgccgccc agcacgcggt caaactcttt
    18961 aaaaccggta gaaaagcgcg gcagttcctc aagactgatg tcagacagtt tctgcacttt
    19021 tgatacgccc gcactgccgg cgtatccgct cagacgttcg ttacgcgcca ccgtcggcga
    19081 cgcggcaagg cgcacctcag taatggtgtt ccaggcctgg caggcgctgc actgcccctg
    19141 ccagcgtggg taatcggcac cacattcatt acaaacaaag gcgcgtttgg gagcttttgc
    19201 cacgttttac ctctttcgtt aacgctgttg ccggatggcg ctggcgctta tccggcctac
    19261 ggtcgccttg ccattgggca gattaatcat ttctggttca tgctgccgga gagaatgcaa
    19321 aacacgccca tcaggtcagc gtggcggatc gtaatctccg tcttttcgtt tacttttggc
    19381 ttggcatgga aggcaatacc taaccctgcc gctttgatca ttggcagatc gttagcgccg
    19441 tcgccaatcg ccaccgtctg cgccagcggg atgtcatgct cttgcgccag acgaagcaag
    19501 gtattggctt tatactcagc atccacaata tcgccgataa cgtgaccggt aaatttaccg
    19561 tccatgatct ccagctcatt ggcgaccgcc gccgtcaggc gtagctggtc acgcagatag
    19621 tcggcgaaga aagtgaagcc gccggaggcg atagcgattt tccagccgag cgcttccagt
    19681 tttagcacca actgcgttaa tcctggcatt agcggcagat tcccgcgcac ctggcgcaaa
    19741 atatcggcat ccgcgccttt cagcgtcgcc acgcggctgc gcaggctggc ggtaaaatca
    19801 agctcgccgc gcatcgcgcg ctccgtcact tcagccacct tctcaccggt accggccagc
    19861 ttagcgattt catcgataca ctcaatctgg atcgccgtgg aatccatatc catgaccagc
    19921 agccccggcg tgcgcaaatg cggaatttta cccagcggcg cgacatccag ctgcgcctca
    19981 tgcgccagcc gcgtcgcacg cggcgtcagc gaccccgcca gacgaatgac ctgataatcc
    20041 tccacgcacc aggcggcgac aatcaccatt gccgcgccca gtttggtctg atattgagtt
    20101 aaacgctgct tatccagccc gcgcccatac agcagccaac cgctgcggcc tgcatggtaa
    20161 tccagaggca tcacctcgtc gccgcttaaa gaaagaggca aaccaggcca taaagagaca
    20221 tcttcaggca gatcgcacca ggtaatgtta ggcattaaag ctcctgtaaa tcgttcaggc
    20281 cggtaaccgc cccgcggaaa ataacgcatg aggctacctt gtaaccatcg cttctggcaa
    20341 cattaagcct caaattttca gcaggtggaa tatggctcgc gcaaaactga aatttcggct
    20401 gcatcgtgca gtcattgtat tgttctgtct cacactgctc gtcgcgctca tgcagggcgc
    20461 gtcctggttt agtcaaaacc accagcgaca gcgcaatcca cagctggaag agctggcccg
    20521 cacgctggcg cgccaggtga cgctcaacat cgccccgctg atgcgcagcg aaacaccgga
    20581 tgaaaatcgc atcaacgccg tgctgcgtca gctcacgcaa gagagccgta ttctggatgc
    20641 cggcgtctat gatgaacagg gcgatcttat tactcgcgct ggcgaaagcg tcaacgtgcg
    20701 cgacaggctg gcgctggatg gcaaaaaagc gggcagctat tttaaccaac aaattgtcga
    20761 gcctatccag gggaaaaacg gcccattggg ctacctgcgt ctgacgctgg atacccacac
    20821 tctggccacc gaagcaaaac aggtcgataa caccaccaac attctacgcc tgatgctgct
    20881 actctcgctg gcgataggcg tggtgctgac gcgcaccttg ctacaaggta aacgcacccg
    20941 ctggcagcag tcacccttcc tgttaacggc cagcaagcct gttccggaag aggaagagcg
    21001 tgaggaaaaa gagtaaaatg acggcttaat aaaggtaagg aaaaccacca tgacaacatt
    21061 acgcctgctt atttctgact cttacgatcc ctggtttaac ctggcggtcg aggagtgcat
    21121 tttccgccag atgcccgcca cccagcgcgt gctgttcctg tggcgcaacg cggacacggt
    21181 ggtcattgga cgcgcgcaaa acccgtggaa agagtgtaat acgcggcgta tggaagaaga
    21241 taacgtccgt ctggcccgcc gtagcagtgg cggcggcgcg gtattccatg acctcggtaa
    21301 tacctgcttt acctttatgg ccggtaaacc ggaatacgat aaaaccatct ccacccatat
    21361 tgtgctcgcg gcgctgaatt cgctgggcgt catggccgat gcttcaggac gcaacgatct
    21421 ggtcgtaaaa acgccggacg gcgatcgcaa agtctccggt tcagcctatc gcgaaaccaa
    21481 agatcgcggc ttccatcacg gtacgctgct gctgaacgcc gacctcagcc gtctggcaaa
    21541 ctatctgaat ccggataaaa agaaacttgc ggcgaaagga atcacctccg ttcgctcccg
    21601 cgtagccaat cttaccgagt tattaccggg tatcacccat gaacaggtct gccaggcggt
    21661 cacggaagcc tttttcgccc attacggcga acgcatcgac gcggaagtga tttcaccgga
    21721 taaaacgccg gatctgccga attttaccga aacctttgcg cgccagagca gttgggagtg
    21781 gaatttcggc caggcaccgg cgttcagcca tctgctggac gagcgtttca cctggggcgg
    21841 cgtcgagctg cattttgacg tagagaaagg tgtgattact cgcgcacagg cgtttaccga
    21901 tagcctgaac ccggcaccgc tggaagcgct ggcggggcgg ctgcaaggct gccagtatcg
    21961 ggcggataaa ctacaggaaa cgtgcgaagc gctgatagcg acgtttccgg aacaggagag
    22021 tgagttgcgg gaactggcga attgggtcgc aggggccgtg cgttaaagaa ttgccggatg
    22081 gcggctacgc cttatccggc ctacaaatga gtgctttctg taggccggat aagcaacgcg
    22141 ccatccggca ttaccgctat tcaccagcgt caagatccct cacctccccc gcccaatcaa
    22201 ccgggtaaac gccattgcga acatcacgat gaaaggtcga aaacggccaa tcctgcaccc
    22261 gccttaccca accgtgcttc acggggttga agtagaggta atcgacatgt cggcgaaaat
    22321 ccttttcgtc gcgaatcgtg tgctcccaga atcgtggctg ccacacgtca tggcgcatta
    22381 tcgatttggt aaataacttt ttaagctccc gccagcgaga tgaaaagtca caatcgttct
    22441 caggaagcgt ccagatgcaa tgcagatgct caggcaacac gacaaaagca tcaatttgaa
    22501 aaggcttcgt atttttcact cggcgaatcg cagagcgtaa ttccgcaatc tggcggacaa
    22561 gtaaatcact tttccggttt ttcagattaa ccgtgaaaaa ccaggttcca ccgttaatgt
    22621 aataacgacg atagttcgac attttgttca ttccttaaac aaaatccaaa cgtaacgggt
    22681 taatagcaaa aggcaatgcg gagagggtaa ttcgggaatg aggctcgcag tataaacagc
    22741 agattgccgg atggcggcta cgccttatcc agcctacaaa tcgatcctgt aacaatcgca
    22801 ggccgttgta ggcccggtaa gcgaagcgcc actgggcaca gcacaatctt actctttatc
    22861 gcccagcagt acggattcca gcgcgatttt gatcatgtcg ttgaaggtcg tctgacgttc
    22921 agcggcagtg gtctgctcgt gggtacggat atggtcagac acggtgcaga tggtcagcgc
    22981 tttcgcgcca aattcagccg caacgccgta gatacccgcc gcttccatct ctacgcccag
    23041 tacgccgtat ttttccatca cgtcgaacat ttcgccgtcc ggagaataga acagatccgc
    23101 ggagaacagg ttgcccacgc gcgcgtctac gcccagcgct tttgccgcgt caaccgcgtt
    23161 acgtaccatg tcgaagtcag cgatagccgc aaagtcatga tctttgaaac ggatacggtt
    23221 cactttggag tcggtgcagg cccccatacc gatcaccacg tcacgcagtt tgacgtccat
    23281 gcgcacagcg ccgcaggagc cgacgcgaat gattttcttc acgccgaaat cggtgatcag
    23341 ctctttggtg tagatggagc aggacgggat acccataccg tggcccatca cggagatctt
    23401 acggcctttg taagtcccgg tgaaacctaa catgccgcga acgttgttca cttcgcggac
    23461 atcttcgagg aaagtctcag caatgtgctt cgcacgcagc gggtcgcccg gcatcaatac
    23521 gacgtcagcg aaatcaccca tttctgcatt aatatgtgga gttgccatct tcagttccct
    23581 ttaaatttgt tgttattgcc tgatggcggc tacgccttat caggcctaca aaacgtgtgt
    23641 aaaaacagtg aaatacccta aggatttcgc gttgtaggaa ggcgacgaat tcgtgaatcc
    23701 ccgggagcat agattaacta tgtgaccggg gtgagcgaat gaagtcaacg catctacagc
    23761 gcgaaagaca acgggtatca cagcatgttt ttaccgtagt ccatcggcga tgtaccaaag
    23821 taggtcgcca gcgtctggcc gatatccgca aaggtttcac ggtgacctaa agagcccggt
    23881 ttgactttcg gaccgtagat cagcaccgga atgtgctcac gggtatggtc agtaccggtc
    23941 cagctcgggt cacagccgtg gtcagcggtc aggatcagaa tgtcatcttc acccaccagc
    24001 tccatcagct ccggcagacg gcggtcaaac agctccagac ctgcggcgta gcccgcgatg
    24061 tcgcgacggt ggccccagga agagtcgaag tcaacgaagt tagtgaaaac gatggtttta
    24121 tcgcccgctt ctttcatctc tttgagggtc gcgtcgaaca gcgcgtccag accggtcgct
    24181 ttcactttct tagtgatgcc gcagttggcg tagatgtcgg caatcttacc gacggacacc
    24241 acgtggccct gtttttcatc gaccagtttc tgcagcacgg tcggcgctgg cggttctacg
    24301 gccaggtcgt gacggttgcc ggtacgctgg aagttaccgg ccttgtcgcc gataaacgga
    24361 cgcgcgatca cgcggccaat gttgtagccg ccttcggtca gctcttcacg ggcgatttcg
    24421 cacagctcgt agagtttatc caggccaaag gtctcttcgt ggcaggcaat ctggaacacg
    24481 gagtcagcgg aggtgtaaaa aatcggcttg ccggttttca tgtgctcttc gccgagctgg
    24541 tccagaatga ccgtaccgga agagtggcag ttaccgagat agcccggcag gttggcgcgt
    24601 tttaccagct tatccagcag ttcctgcggg aagctgtttt cgtggtcgct gaaatagccc
    24661 cagtcgaaca gcaccggcac gccggcgatt tcccagtggc cggacggcgt atctttgccg
    24721 gaggacagtt cgtgcgccca tgcgtatgcg ccaataacgt ccgcgttgcc gtccatgccg
    24781 gcggcaattt taccggtaga gccttcatgc gctttcacca gccccagacg agtcaggtta
    24841 ggcagattca acgggccctt acggccattg tcagcttcgc ctttggcgca agcttctgcg
    24901 atgtggccca gagtgtcgga acctacgtcg ccaaaacgat ccgcgtcttc agtagcgccg
    24961 atgccgaatg agtccagcac cataataaat gcacgtttca tatcttctcc gtacttagtg
    25021 cttcaaaaat aattgatcag atcagtatac aactattcag taattcgacg atagaccgaa
    25081 ggtgtgcttg ctggcgcttt atcgtcaagg ataattgccg ctttgacggc cttcgccgct
    25141 tcctgccaac tggcttcgtc tttggcatga atcaccgcca gcgggcgctg cccgtcgatg
    25201 ctgtcgccca gacgggccat gtcggtaaag ccaacgctgt aatcaatggt atcagacgcc
    25261 tgacgacggc cgccgcccat cgagacgacc gccatcccca gcgcacgcgt atccattgcg
    25321 ctgataaacc cttcggtatc agcatatacc gctttgctca acatggcggt cggcaggtat
    25381 ttatcgtagt tctcaacgaa atcgctcggc cctttctgcg cggccaccat acgaccaaag
    25441 acttctgccg ctttaccgtt atccagaacc gcctgtaatt tcgcacgcgc ttcggcgtcg
    25501 tctttcgcca gctggccgga gatcagcatc tccacgcata gcgccatggt aacgtcaaac
    25561 aagcgcggat tgcggtattc tccggtcagg aactgcacgg cttcacgcac ttccaccgcg
    25621 ttaccggcgc tcgaagccag cacctggttc atatcggtta acaaagccgt agtgcgaact
    25681 cccgcgccgt ttgccacgcc aacaatcgct tcagcaaggg cttcagaaag ttcataggtt
    25741 ggcataaacg cgccactgcc gactttgacg tccattacca gcgcatccag cccttcggcc
    25801 agtttcttgg cgaggatgga accagtgatc agcggaatag agtccaccgt cgcggtaata
    25861 tcgcgggtgg cgtaaaaacg tttgtccgcc ggtgcaagcg agctggtttg cccaataatc
    25921 gccacaccca cgtcttgaat aatttcgcgg aaacggttgt cgtccgggaa gatgtcgaag
    25981 cccgggatcg cttccagttt gtcgagcgta ccgccggtat gtccgagacc gcgaccggag
    26041 atcatcggca cataaccgcc gcaggccgct accattggcc ccagcatcag agacgtcacg
    26101 tcccctacgc cgccggtcga atgcttatcg acaatcgggc cattgagatt caggcttttc
    26161 cagtcaagga cagtaccgga atcccgcatc gccatggtca gcgaaacacg ctccggcatg
    26221 gtcatatcgt ggaagaagat ggtcatcgcc agggcggcaa tctgcccttc agagatagta
    26281 ttgtcacgaa taccattgat aaagaaacga atttcttcgt cactcaacgc atgaccatca
    26341 cgctttttac gaataatttc ttgtgcgaga aacacggtac cctcctgagg gaaaagagta
    26401 gaaggcttac atcgccggat ggcggctaac gccttatccg gcctacaggc ctggatttgt
    26461 aggccggaaa gcgcagcgcc atccggcaaa tcagagctta gtagctgctg gcgctcttac
    26521 cgtcgccgtg acccagcgct ttcagcaggc ttgccagcag gctggatgcg ccaaagcggt
    26581 agtgacgaga atctgcccag ttagcgccaa acagttcgtc tgcgatcgcg aggaatttct
    26641 gcgcgtcttc cgccgtacgt acgccgcccg ccggtttgaa gccaacggtt ttggaaacgc
    26701 ccatgtcgcg gatcacttcc atcatgatgc gcgcgctttc cggcgtagcg tttaccggca
    26761 ctttaccggt agaggttttg atgaaatccg caccggcttt aatggagatt tcagaggctt
    26821 tacgaatcag cgcctcttct ttcagctcgc cggtttcgat aatcactttc agcaatacgt
    26881 tcgctgcggc acaagcgtct ttacaggctt ttaccaggtc aaaacccacc tgctcgttac
    26941 cggcgatcaa cgcgcggtac gggaatacca cgtccacttc gtcagcgccg taggcgatcg
    27001 ccgcacgggt ttccgccagc gcaatatcga tgtcatcatt gccatgcggg aagttagtca
    27061 ccgttgcaat gcggatgtcc ggggtacctt gttctttcag agttttacgc gcaatcggga
    27121 taaaacgcgg gtaaatacaa atcgccgccg tattcccgac cggggttttt gcctgatgac
    27181 acaacgcgat cactttttca ttggtgtcgt catcgttcag agtggtcaga tccatcagtt
    27241 tgagcgcacg caggctgctt gcttttaaat cagtcatgac attctccaac ggcattgccg
    27301 tataaaattt caccttgcga gtctgttaat attctaacat tcactcgcga ttacacttcg
    27361 atatacatca cagttaatga aaactacgta caaatttgca ttactgtaat gagatctgaa
    27421 tcaaattatc ccgccgtcac cgcctgttct tcgagcgtta agcgcatcag gatcaaagtc
    27481 ggtttgccgc cattttctac aatagcgcat cgtcccggca taaagaggaa acgaagatgc
    27541 ctgcctcatg cgaaactgcg ctccagcagc gttgccagca aattgtgacc agcccggtgc
    27601 tcacgcctga acaaaaacgc cattttctgg cgctggaagc tgaaaacgcc ctgccttatc
    27661 ccaccctgcc ggaagatgcc cgccaggcgc tggatgaagg cgtcatttgc gatatgtttg
    27721 aggggcacgc ccccttcaaa ccgcgctacg tgttgcccga ttacgcccga tttctggcta
    27781 acggttcaca gtggctggaa ctggaaggcg cgaaagatct ggatgatgcg ttatccctac
    27841 tcaccattct gtatcatcac gttccttccg tgacgtccat gccggtttat ctcggccagc
    27901 ttgatgcgtt gctgcaaccg tatgttagaa ttctaacaca agatgcgatc gatattcgaa
    27961 taaaacgttt ctggcgttat ctcgacagaa cgctgccaga cgcctttatg catgccaata
    28021 ttggccctgc cgatacgcct gtcacacgag cgattttgcg cgccgatgcc gagttaaagc
    28081 aggtggcgcc taacctgacg tttatctacg atgcggaaat tacgccggac gatctgctgc
    28141 tggaggtcgc caaaaacatt tgcgaatgca gtaagccaca catttccaac ggccctgtaa
    28201 atgataaaat tttcacaaaa ggccattatg gcatcgtcag ttgttataac tcgctaccgc
    28261 ttgccggcgg tggcagtacg ctggtacgtc tcaacctgaa agccgtggca gaacgcagta
    28321 cgtctgtcga tgacttcttt tcacgcacgc taccgcacta ctgccgacag cagatcgcca
    28381 tcattaattc acgatgtgaa ttcctctatg aaaagtcaca tttctttgag aatagcttcc
    28441 ttgtacagga aggtttgatc gatcccgaac gttttgcgcc gatgttcggt atgtacgggc
    28501 tggcggaagc cgtgaacctg ctgtgcgaaa acgccggcct gaccgcccgt tacggcaaga
    28561 atgaaacggc gaacgagctg ggctaccgta ttagcgccca actggcggat ttcgtcgaaa
    28621 atacgccagt gaagtatggc aggaagcaac gggcgctgct ccatgcccag tctggcatca
    28681 gttccgatat cggcactacg ccgggcgcgc gtctgccgta tggcgatgaa ccggacccta
    28741 tcacccattt gcaaaccgtc gcgccgcacc atgcctttta tcatgccggg atcagcgaca
    28801 ttctgacgct ggacgaaacc atcaagcgca atccgcaggc gctggttcag ctttgtcttg
    28861 gcgcgttcaa agccgggatg cgggaattta ccgccaatgt cagcggcaac gatctggtgc
    28921 gcgtcaccgg ttatatggtg cgcctgtcgg atctggcgaa atttcgcgcc gaaggctcgc
    28981 gcacgaatac cacctggctg ggagaagaag ccgcacgtaa tacccgcatc ctggaacgac
    29041 agccacgcgt agtcagccat gaacaacaga tgcgctttag tcagtaagat cattgcgttt
    29101 tcctgcgtcg atgggccagg cagccgcctg gcattattct tacagggctg caatttgcgc
    29161 tgcaagaatt gccataaccc gtggacgatg ggacgctgta acgactgcgg ggaatgcgta
    29221 tcgcagtgtc cgcaccacgc cctcagcatt gatggcggga aagtggtatg gcggtcggac
    29281 gtctgcgagc agtgcgatac ctgcctgaaa atgtgcccac agcaggcaac gccaatggcg
    29341 cagactatga gcattgacga tgtgctgcgt catattcgta aagcatcgct gtttattgaa
    29401 ggtattaccg tcagcggcgg agaggcgacc acgcaattac cgtttattgt ggcgctattt
    29461 acggcgctca aagccgatcc gcagttacaa cggctgacct gtctggtgga cagtaatggt
    29521 cagttaagcg agaccggctg gcaaaaacta ctgccggttt gcgacggcgt aatgctcgat
    29581 ctgaaagcct ggaagagcga gtgtcatcac cgtctgaccg gacgtgataa cacgcatatt
    29641 aagcacagta tccgctttct tgctgcgcgg ggaaaactgg cggagctgcg gttgctggtt
    29701 atcccgggtc aggtggacta tgcggcgcat atcgattcac tggcggcgtt tattacttcg
    29761 ctgggcgagg ttccggtgcg cctgaatgcc tttcatgcgc atggcgtcta tggcgaagcg
    29821 aaagcctggc caggcgcgac gccgcaagag gtggaacggc tggctgacgg attgcgcgcg
    29881 cgtggggtgg cgaagctgat tttgccggcg ctatatttgt aagcgtcgcc tgccggacgg
    29941 cggctgcgat gccatcagag ccgaaacaag gtaacggtat tgcgatacag cgtatcggct
    30001 atcacctctg cgggctccgg acgtaattcg cagagcgcat caaatacgcg cgccgcctgc
    30061 tccgggcggt tcggctgccc ctgaaacccc tttagcggca tatccggcgc atcggtctcc
    30121 agcaacagcg cgtccagcgg caaccgcgcc ataacatcac gggttttact ggcgcgcggg
    30181 taggtgatgg tgccgccgac gccgatttta tagcccagtt gcacaaaacg ttcggcctgt
    30241 tgcagactgc cggaaaaacc atgcaccaca ccggtttgcg gcaaactctg gcgctttaag
    30301 cgcatcgcca gtttgtcatg cgtgcgccgc gagtgcagga tcaccggcag atcgtagcgt
    30361 tttgccagtt gcagttgcgc gtctaaaaat cgctcttgcc tggcgaactg cggatcgtcg
    30421 cgataaagat cgagaccgat ctcgcctacc gccacgacgt tctgttgttg cgccagcgct
    30481 tgttgcagct tatcaggatc gtcatcggca tgacgctcaa tcacaatggg gtgcaatccc
    30541 agcgcagcat aaagcgacgg gaaacgcgcc gccagcgcca gcacgcgggg aaagtgagcc
    30601 gcctcggtcg ccggcacgat gattttttca acgcccgcct cacaggcacg ctgaatactg
    30661 gcgcgctcat cgcccgtaaa gggcgggaaa tcaaaatggc aatgcgtatc gataaagcgc
    30721 cagctcacgc cagatcctcg tcggtaaatg tggtgtcgtt tgcctgcggc gcgctaatga
    30781 cctccgccac atgcgtatca ttggccaccg gtgccggagg cacgaccacc gtttccggca
    30841 cggcaatccg cgacgaatgg cgcaagagag gcggcgttgc ggcgagcaat ttaccaacgg
    30901 tggcaaggaa ataacgcccg cataattgcc cggttttgta atcctcacgc agcgccggga
    30961 tacggctgcc cagcgccatg ctgtgcagcg gtttcggcgg ataaatttca atgatccgca
    31021 gcttacccgg cggcttttca ataaattgtt ggatcgcgct gtaggacgtt tcatgatgct
    31081 gcaccaggtt gaccaacggc tgtagactgc tctctcccag ccagcgctcc atacgcttaa
    31141 accactgcgg cgtgtaatac atttgcgagg gtacggtgcg gatcaccaca atggttttcg
    31201 ccccccgctt tgccgcctcc tgaaccggaa tggcgtcgct aatgccaccg tccagatagt
    31261 tgatgccctc taacgtaacg ccggtacggt agaaacccgg tatggcgctg gaggcgcgaa
    31321 tgatatcaag ccagttttgt tttgtcggcg agaaatagcc cggcgtgtaa tcatcccccc
    31381 ggcaggcgca catataaaag gattttccgc tgtcgaacag gcgcgctgag gtatccatct
    31441 gcagcggcat ccgggcggcg gtggactcca ccagccagtc gaggtcgata aggtttcctc
    31501 cgcgtacaaa tcgcagcgga tcaaaaaatt cgcgcctggt ggtatagcgc ataatgactt
    31561 tacgcccgta gccgggctgg ttgcagagat acgccgagag attttgcgca ccggctgatg
    31621 tgccgaagta gagatggaaa ggattaaact gcgcacgcat aaactcatcc agcacgcctg
    31681 cggtaaagat gccccgctgc cccccgccct cacagaccag cgccatacgg cctgaccgga
    31741 acggtgttaa tgataacggc gcaatattgc cgagcgtaac cggtattcgc tggcccacct
    31801 ctgccttcct gtttttcatt tttttccagg ctgacaaggt aatgcaaaac gttaacggct
    31861 aaaaccgtaa aagccagtcc gctggactgg cttgatagca atatatcttt acagctgcct
    31921 gctagggtcg tttacggccc atgaacaggc tgaccaggaa gagcacgatc ccgacgacga
    31981 agacgatttt cgccgcgccg gcagccgtac cagccagtcc accaaaaccc aatgcggcgg
    32041 caattaacgc gataaccaga aatataatgc cccaacgaaa cataagcctc tcctttacca
    32101 tagttaatgt cgaccgctaa atatgagcgc tcaggctact cattcgcgat atttttagtg
    32161 tggtgcacat tacgcctccc gacaaacgtc gggaggacga attacgacga attactgaac
    32221 tttcagatcg tttttaacac tttttacgcc atcaacggct ttcgcgatgc tttcagcgcg
    32281 gtcgctttgt tcctgagttt caacagtacc ggagagctgt acgacgccat cggtcgtttc
    32341 cacttttact ttacgggaag ggacgagatc gtccgccagc aacttggctt tgacttcact
    32401 ggtcgtggcc gtatcgccgg cataaccttt cacggaacct tctttattgt cgcgaacgtg
    32461 aagtttgtcg ctaacggagg tcacgccttc tacgcctttc gccactttca cggcggcttc
    32521 agcctgcgcc tggctttcta caaagccgct cagggtgacg actttctgat tggtttcgac
    32581 agaaatatcg gtgcttttaa tattgtcatg gtctaccagc gcagctttga ctttcgcagt
    32641 gatagcgctg tcatccatga agttaccgac tttattcata gagctatcga ctttttgccc
    32701 tgcggtttcg gttccgcttt gcgccttgtc cgttgttgcg ttttctgcaa aggcagaacc
    32761 tgtcgcaaca gcagaggtca acattacggc cagcagagtt ttagaaatct tcagtcttgt
    32821 catagtcatc gattttgtcc tgtatagttt gctcgtaatt tgagctcagg caacacgagg
    32881 ttgcattgct gaatgcggtg aaactcaccg gtttctgaag tcaatgactg gcatcacatt
    32941 cgtgaatttg taacgacgcg tcgcctgcca cccttccgtt tcagttatta atatcgtgac
    33001 tgaaacaaat ctcagcttta agctctcata ttcacgcatt gaacaggcat taaagccgac
    33061 atttatgtca tcactttgtt aaatatagat cacaatttta aaatcgcttg tcggtgcgta
    33121 taaaaaacag gcagatcgga gaaaaaacgc gggatttaag aacattccgt aagcggttaa
    33181 aaaggcaggg aaagtacgaa ggcgcggcgg atgccgcgcc cggaaaggga tcagtgttcg
    33241 cgcgttttac ggaactgaac gtcagggtaa cgttcctggg tcaggttcag gttaaccatc
    33301 gtgggggcga tataggtaag gttgtcgccg ccatccagcg ccagctgcgt ttcattctta
    33361 cgcttaaact cttcgaattt cttcgcatcg gcgctttcca cccagcgcgc cgtcgccacg
    33421 ttgacggatt cataaatcgc ctcaacgttg tattcgcttt tcaggcgcgc gacaacaacg
    33481 tcaaactgca aaacgcccac ggcgccgaca atcagatcgt tgttggagat gggacggaat
    33541 acctgcaccg ccccctcttc agaaagctgc accagccctt tcagtagctg cttctgcttg
    33601 agcggatctt tcaggcgaat acgacggaac agttccggcg caaagttcgg gataccggta
    33661 aacttcatca tctcgccctg ggtgaaggta tcgccgatct gaatggtgcc gtggttatgc
    33721 agacccaaaa tatcgcccgg gtacgcttct tcaacgtgcg aacggtcgcc cgccataaaa
    33781 gttaacgcgt cggaaatcac cacatctttg ccggtacgga cctggcgtag cttcatgccc
    33841 ttctcatact taccggaaac cacgcgcata aacgccacgc ggtcgcggtg tttcgggtcc
    33901 atattggcct gaattttaaa gacaaaaccg gtgaacctct cttctgaggc ttccactgtg
    33961 cgggtatcgg tttgacgcgg catcggcgcg ggcgcccacg ccactaaacc atccagcata
    34021 tggtcaacgc caaagttacc cagcgcggta ccgaaaaata ccggggtaat ttcccctgcc
    34081 aggaacagct cttcatcaaa ctcgttagat gcgccctgca ccagttccag ctcgtcgcgc
    34141 agttgctgcg ccaggtcttc accgacggcg gcgtccagat ccgggttatt cagcccttta
    34201 acgatgcgca cttcctgaat ggtgtggccc ttaccggtct gatacagata agtttcatct
    34261 ttataaaggt gataaacgcc cttaaacagc ttgccgcagc caatcggcca ggtgatcggc
    34321 gcacagccga ttttcagctc attttccact tcatccagca gctccatcgg gtcgcggatg
    34381 tcacggtcga gtttgttcat aaaggtcagg atcggcgtat cacgcagacg ggtaacttcc
    34441 atcagcttac gagtcctgtc ttcaacacct tttgcggcgt cgatcaccat cagacagcag
    34501 tccaccgccg tcagggtacg gtaggtatct tcggagaagt cttcgtgccc cggggtgtcc
    34561 agcaggttca ccagacaatc gtgatacggg aactgcatca ccgaggtggt gatagagata
    34621 ccacgctgtt tttccatctc catccagtca gattttgcat gttggctgga gccacggcct
    34681 tttaccgtac cggcggtctg aatcgcctgt ccgaacagca acactttttc ggtaatggtg
    34741 gttttaccgg cgtccgggtg agaaatgatg gcaaaagtgc ggcgtttggc cacctcttgc
    34801 aaataaggag acaacgtcat agtcaaatct tcttgagtaa gcgcggcgtt tgaccacgca
    34861 tgttgaatac gaaaaatgcg gctattttac ccatcaacct gggggaggca atcagtgttt
    34921 acacaggagc tgctccagtt cgcttaatga cgccacagtc caggttggat ggatacccgc
    34981 gggctgctcg cgatgatgcg cgttaagcca gcaggtcgac agtccggcgt taatgccgcc
    35041 aagaatatcg gactccgcgg tatcgctaac cattaatacg cgcgagcggt caggattccc
    35101 cgcctgctcc agggcgtagt taaagatttt cggatcgggc ttcgcgacgc caacctgctc
    35161 ggaaatcacc agcagatcga aatactcgcg cagcccggtg cgctccagac gagtttgttg
    35221 tagcgcggta aaaccgttag taataatacc gattttagcc tgcccgcgaa tcgcattaag
    35281 tagcgaaacg gcgcccggca aaggagaaca gatctccgcc atcgcactaa taaaagcgtc
    35341 attcagccgc cccggcgcaa cgtttagccg ttcagcccaa ctttgaaagc gcgcgtgctg
    35401 caattgtaat gaagtaatcg cgccgttctg ataatccacc catagcggct tattcacggc
    35461 ctggtaatcc tggaaatcct cagcggtaaa ggtgacgcta tagtcaagga acatccgctg
    35521 taagccggtg aaagaatcaa acgtaaacag cgtttcatcg gcatcaaaga aaatccagtc
    35581 ccacttcatc attacacctt gcctctttta ttacatgctt atcggtaacg ccatgatgat
    35641 ggcgtcctca tgcccttgtg ccgtgggata gtaattgcgg cgaatcgtcg cctcgttaaa
    35701 ccccagactt tcatacagcg cgatggcggc agcgttagag gcgcgtacct ccagccataa
    35761 cgttacaaca ccgcgttttt ccagttcatc aatcagatgc tcaagcagca tacgccccag
    35821 cccccgacgc tgaaaatccg gatcgacggc gatattgaac agcgtcgctt cgtccagcac
    35881 cacctgtgta atggcaaacg cggccattct gtcatcagca gtcagcttaa agttgagata
    35941 ccgttcgccc tggttgccga aaaacgtttt ttcgctccac ggaaacgcat gagcgcgttg
    36001 ctcaatctgc caggctgcgg ggagatcggt cgtgctgagg atagaaatcg tgttcatgtt
    36061 cgcagatttg ttgccatagt gcggcgcgtg ccgccgggtt tacccggagt tcattaaacg
    36121 ccggcgtcgt gacctgagcg ccttcgagtt ggagcggcgc gtcagttcct aaccgccagc
    36181 tattacaacg gctgccctgc ggcagcatgg cgacgcgctc aggcgtcagc ggtaaaacct
    36241 gatcgggact cacggtcaac gcgcgtaaaa tatcgcgcat tagcggctcg ttcagcgcgg
    36301 gtaattcctc tgcaaccacg atcagacgaa cgtgcgcggg aagggaaatc gcaatctcgc
    36361 cctgtagcgc gccaggacgt cgcagcgccc actgcgtaat acccagttgc tgtaactgcc
    36421 agtctcgtcg ggatgtcata gcgaaacgct cctgtaatca ggggcgcaaa tatagcaaat
    36481 ctgtcgaatc tccgccatca aactactata atcgccgcca gtctgaatta aggagcattc
    36541 catgtctgct tttaccccgg caagtgaagt cttgctgcgc cacagtgatg atttcgaaca
    36601 aagccgtatt ctttttgccg gagatttgca ggatgacctg cccgcgcgct ttgaatgcgc
    36661 cgccagccgc gcgtatacgc aacagtttca ccactggcag gcgttaagcc gccagatggg
    36721 cgataacgtc cgttttagcc tggtcgcgca agccagcgat gtcgctgact gcgatacgct
    36781 gatctactac tggccgaaaa ataaacccga agcgcagttc cagttgatga atattttgtc
    36841 gctgatgccg gtgggcagcg atgttttcgt cgtgggagaa aaccgcagcg gcgtgcgtag
    36901 cgccgaaccg atgctggcgg actatgcgcc gctgaacaaa gtagatagcg cgcgacgttg
    36961 cggcctttac catggtcgtc tggaaaagca gccgcagttt agtcttgaat cctggtgggc
    37021 cgagtacaat atcgacgggc tgaccatcaa aacgttgccg ggcgtattca gccgcgacgg
    37081 actggatgtt ggtagccaac tgctgctgtc tacgctgacg ccgcacacca aaggtaaagt
    37141 gctggatgtc ggctgcggcg ctggcgtgct ttccgccgcg ctggccagcc attcgccgaa
    37201 agtgcgcctg acgctgtgtg acgtcagcgc gccggcggtg gaagccagcc gcgccacgct
    37261 tgccgctaat ggtcttgaag gcgaggtatt cgccagcaac gtcttttcgg aagtcaaagg
    37321 acgttttgac atgatcatct ccaacccgcc gttccacgac ggaatgcaaa ccagccttga
    37381 tgcggcgcaa acgctcattc gcggcgcagt gcgccatctg aacagcggcg gagagttacg
    37441 catcgtggcg aacgcctttc tgccctatcc taagattctg gatgagacct ttggcttcca
    37501 tgaagtcatc gcgcaaaccg ggcgctttaa ggtttatcgt atcgtgatga cccgtcaggc
    37561 gaagaaatag ttggcctgat aagcgcagcg ccatctggtt gcatgtgccg gatggcgacg
    37621 ccaggcgtct tatccaacct acgtctcgcg cccatttttg cagcaatcaa tctatcccat
    37681 gcaattaact attgacgaat agctgaaaac cactagaatg cgcctccgtg gtagtgattc
    37741 ttttcaagaa tcgatggtat gcgaaggtgg cggaattggt agacgcgcta gcttcaggtg
    37801 ttagtgtcct tacggacgtg ggggttcaag tcccccccct cgcaccaaaa ccatgttgat
    37861 attgctcgca ctgggcgaag gtggcggaat tggtagacgc gctagcttca ggtgttagtg
    37921 ttcttacgga cgtgggggtt caagtccccc ccctcgcacc aacgaggcga tatcaaaaag
    37981 taagataact gtgcgaaggt ggcggaattg gtagacgcgc tagcttcagg tgttagtgtc
    38041 cttacggacg tgggggttca agtccccccc ctcgcaccaa ttatcttatc cttcctttgt
    38101 cccttcattt tcatccctga ttccagttca tcattgccaa catcatgccg ccaataagcg
    38161 ctatacacga tggcagcagt acaaaatgcc gtaattgttt gtgatacaac atcagcgcag
    38221 acagtagcaa tcctgataca atcaacagct tcagcgcata agctgacagg ccgataaacg
    38281 ccagtccaac gataatcact ccaggcaata acacgcccca tccgctgcct aacgtccgct
    38341 gcaacatggt ttcacctctg gaattgataa tgataaccaa tatcatatga tatattttct
    38401 catttgtcag ccagggagaa agctaaagag atgagtttta cttaacggtt gatgacacgt
    38461 attcagtaag gtgataaatt gtccgactgt taacgtaaaa acaacaacac ctcgctttag
    38521 gcgacctttt ctcatacgtt attttcatgt tggcgcccga ttccgtgtat atcactgata
    38581 aataacgaca attacccatg acaacaccat cctggcggtc gcttcgtatt aagaagtatc
    38641 agttttcttt acgtcttttc ttgtttctca gcgccgtgtc ggcgctattt actctcgttt
    38701 tcccccttta tcagatcaat gtattttgca cgccaatgat cgggatagtg ggcctgagcg
    38761 tattactgtt gatatggcat gggaaatatg ggcaaaaaag aattaacctc ccctttatct
    38821 ccctactctt tgggggaata tgggcggcgc gtattgcgct aaagtatccg gcgttaggcc
    38881 attatgattt ctctttttta ctgatctccc tgcttagcgt tctgtttatc ggctcgatag
    38941 cctttgccgc gaatatcgtc gcgtttacgc tctattcgct accgccagtc gcggtctgcc
    39001 tgtggttgaa cggtaatgaa caaggtttgc gaattctcta tttgctggcc ctgccaatgg
    39061 tgggaatcgc tattcaacat gttatccaga aacgctacga taattttgcc caacagctca
    39121 tgtttaagct gctggccgag cgggaaaccc tcaatggcct gagtatgctt gatccattaa
    39181 ccggcttata taaccgccgt ggcctgcaaa atcggctgga tacgttacag gcgccgggca
    39241 gccatgaaca ctacgtcctg ctattggata tcgatcattt caaagcgtat aacgatcact
    39301 acggtcatat gatgggcgat caggcgttaa tccgcgtctc agcggcaatt cgggacgccg
    39361 tgcgatcgcg cgatgtcgtc tgtcgttttg gcggggaaga atttctggtg ttgctgacca
    39421 ccgccgaacc acagcaagcc cgcgctaccg cagaacgtat ccgacaggaa gtatacgatc
    39481 ttaaaatccc gcatatgttt aacgaaagcg tcgccaccaa tgtcactgtc agtatcggca
    39541 ttgcgccctt gacggatcgc aatatcggag acgctatcga aaaagcggat aaagcgctct
    39601 acgaagccaa gcatcttgga cgtaaccaca ttctggtcag cgacgacatg cgcgccctat
    39661 gaatcctgtt ggcgtaatcg tgctacgcca acagcgttaa ccataaaccg cttgccatcg
    39721 tttatcgcta tcgataggat tagcaatcat tatcatttag attaacatca ttaaactgcg
    39781 ctatggccta ccgttccgca ccgattgctg acgatattat ctggcgagct gctccccagc
    39841 cggaagacgc ctcgctggcg gacgcagtac gcgagacgat cgcctctacc cgtcagcacc
    39901 tgttggactt catccggctg gatgaaacgc cgccgccaac ggcgatgact cttgcccagt
    39961 ggacgcgccc cgcgacgttt cgttcattgc tggccgccta ttccgatcac atctatcggc
    40021 acacgccagg cctgccacgt gaaaataagc cgttactctc cctgtgggcg caatggtata
    40081 tcgggctgat gacgccgccg ctgatgctgg cattactgac gcaagcgcgc gctatcaatg
    40141 tctcggcaga acatattcac gttgaatttc atgaaaccgg gcgcgccgcg tgtttctggc
    40201 ttgatgtgca tcaggataac ctggcaacgg aacgttcccc ggaagaacga atggaaacgc
    40261 taatagtctc cgcactacag ccggtcattc aggcgctgga ggcgactggc gacatcaacg
    40321 cgaaacttat ctggagcaat accggttatt taatcaactg gtatctgact gagatgaaac
    40381 cgctgcttgg cgaagccctg ctggcaacgc tacgccagcg ctgttttttt gaaaagcagc
    40441 tatccgacgg tcaggataac ccgctgtggc ggaccgtcgt aatgcgcgac ggtcttctgg
    40501 tacgcagaac ctgctgccaa cgttaccgct tacctgacgt acagcagtgc ggcgactgca
    40561 cgctaaagta aaccgcttta cgttgccttc agttatcgtc acggcttact gctgctggcc
    40621 tgtcacatta ttatatttac agcggcgctc tccgtatgcc aaattacgtt ttgccatttt
    40681 tgggtctacc gtggctattg gtaaggtctc aggagagaag aatgagtctg caatctgtac
    40741 ggcaatttct ggccgctcat gctcccgata ttgaaattat cgaattaaat caaagtacag
    40801 cgactgtcga actggcagcc aaagcgcaca acgtagagcc agggcagata gctaagacgc
    40861 tctcgcttaa agtaaaagac accattatcc tggtggtcgc gaaaggcgat gcccgcctgg
    40921 ataataagaa gcttaaaacc actttcggcg caaaagcccg tatgttgagc agcgatgaag
    40981 tggtcaatgc aaccggacat cctgtcggcg gcgtatgtcc tttcgggctg gagcacccgc
    41041 tgcccgttta ttgcgacatc tctctgaagg ggtataacga agtattgcct gccgcaggcg
    41101 ccacgcacag cgcggtacgc atcacgccgg aaagaatggc tgaactgaca tcggcgacct
    41161 gggtagacgt gtgccaataa cgtgcctgac acccggattc cccgaacaag cacggcgcat
    41221 ccggcgcggg ctatacccga tgctggagcg cggtagcatc tccggcgcgc agatataaca
    41281 gaatatccgc cgcatcgagt aacccggcat cagaactcac gcccagcttg gacatcacat
    41341 taaacttatg cgcccggata gtcttaatgt tacgttctaa ctggacggca atttgcggca
    41401 ttgagtagcc gttcgacatg aaacgcagaa tctcccgctc ggttggacta agcatacaat
    41461 tctggtgaag ttcccaaaga ttgtctgtac gctccgttgt ccgccgggcg ctattaagcg
    41521 atgtaaataa ggcatcctgt aaaacatcca acggcgacgc tttgctgatg accccatcca
    41581 gcggcagcgg ggataatgcg ctgattaagc gggcttcagc atcatcatcg gcaatcacca
    41641 gacgccgcat atggggataa tttatcgcca gttccgtcag gctggataat cctgtccggc
    41701 gttcagttct taacgcagaa agagaaaaaa taacggcaga aaacggcgtc tttagcgcag
    41761 ccttataaaa cgcggatggt tttgaaaaaa tatgaagcgt atgtcggcaa tccggcattg
    41821 catcaaatag ccctttaata ccaatggtgc tcatcacgca tttttctacg agcgcaacat
    41881 ttctcttgct gattctgttt tccattccat ggtttctcca tataccgaag gtaggttcaa
    41941 ttctctggct ccctgagaac tgtttatcca tgcatacatc tctgcattac tgtgtattga
    42001 taagcgtcgc atggcgctat ttttttgggc gctaattgtt ttattacttt ttttaagtaa
    42061 cgccgcaatt tggttaatgc cccacccttt tcctaaaagg cgtaatactt ttcgttcaga
    42121 cagcgtaagg acaatcggcc tgtcgtggga ctgctgaatt tcagacggta cctgaggcga
    42181 taataacgtt ttacttattc tttctgagcg agcgtttccc gcatggataa cgctaataag
    42241 attctcgatt ggctcttcgt ctgaaagcaa ggtgctgacg gggcccatca ggagatcaac
    42301 cgcatgtgga tagcaggatt taggaaccag aaatacccaa tgtatgtcgc gatattgcga
    42361 gattaagcta taaaaatatt cgcagatagc gcggggagag gcattgttaa ctgctaaatc
    42421 agcaataact aaattacttc ggcgtagctg tagcagcgtt agctcttcta tcgtacgaca
    42481 atacgccagt ttataatcgg ggaaattacc tgttatagcc cctttaaggc cttcctgtat
    42541 aagaggggtt ttactgataa taagtccatt tttgcagcat cctggcagca taattcctcc
    42601 gcacccacgc cgccactttt cattgcccca ttaataaaaa cactattaac aatgatcgca
    42661 aagaaatata ggccgagtgg attaattatc cttgttttat ttttaaatat ctaacattga
    42721 ttgcgctaca atccacatag cacaaaaaca tgaaatcact atcgcatagt tactcataaa
    42781 accagaagca agacaattaa attaactaaa tttgcacatt agcaattcta acgaaaacgc
    42841 atcatattaa taaatttaaa atatgagttc gcccttcatt catattgctg agtcctaaaa
    42901 caaaagccca acaatactgt ccaccatcca taaaacccat gtaatatcta cgaattacac
    42961 taagtcatgc ctatttttac acccgctgct cacgccattg tggttaaacc attaatgcat
    43021 atagttgata aaattcacca catcattgat tcaaaaatga gcggccagac tggcataatg
    43081 cctctattct ggaaacggac atacgagaac cgtcgcccat aaggatatcc tgcctgtgac
    43141 gaagcgcacg tctcaggaag cttatgcgtt gcgtctggtg gttgacgttt ttatcaacaa
    43201 gaaattgatc ttaaccaacg ccatcatgcc tgcgcttcgt gttaaaaaga aagcctctgt
    43261 catagtggcg gcgcatagaa tgtcttttcg gacaggacga gtcatgcaag aagagcaatc
    43321 aattcaacga gcagtaacac ggttatgtat tcaatgcggg ctgcttttat tgcagcacgg
    43381 ggcggaaagc gcactggttg atgagctttc cacccgcctc ggtttggcgc tcggtataga
    43441 tagcgtcgaa agcgcgatct cctctaacgc cattgtcctg acgaccatta aagacggaca
    43501 atgtctgaca tcgacacgta aaaaccagga tcgcggcatt aatatgcacg tcgtcacgga
    43561 ggttcagcat atcgttatcc tcgcggaaca tcgtctgctg gattacaaag gcgtggaaaa
    43621 acgctttagc cagctccgcc cgctgcgtta tccgcgctgg ctggtggcgt ttatggtcgg
    43681 tctttcctgc tcctgctttt gtaagctgaa taatggcggc tgggatggcg cggttatcac
    43741 ctttttcgcc agtatgatag ccatgtatat ccgccagatg ctggcgcagc ggcatttaca
    43801 tccgcagatc aatttttgca ttaccgcctt tgtcgctacc acgatttccg ggctgatgct
    43861 cacccttccc gcctttagcc agacgcccac tatcgccatg gcggcgagcg tactgctact
    43921 ggtgccgggc tttccgctga ttaattccgt cgcagatatg tttaaaggac atattaatac
    43981 cgggctggcg cgctgggcta tcgccagcct gttgacactg gccacctgtg tgggcgtagt
    44041 gatgtcaatg acaatatggg ggctacgagg atgggtataa tcgacttttt actggcgcta
    44101 atgcaggaca tgatcttgtc tgcgatcccc gccgtcgggt ttgcgatggt ctttaatgtt
    44161 ccccaccggg cgcttccgtg gtgcgcgcta ctgggggcgc tgggtcatgg cttgcgtatg
    44221 ctgatgatga gcgcaggctt taatatcgaa tggtcgacgt ttatggcttc gctgctggtc
    44281 ggcagtattg gtattcagtg gtcacgctgg tatctcgctc accctaaagt gtttaccgtc
    44341 gcggccgtga tcccgatgtt tccggggatt tccgcctata ccgcgatgat ttccgcagta
    44401 aaaattagcc atctgggcta tagcgaaccg atgatgatta cgctgctgac caattttctg
    44461 aaagcctctt ccattgttgg cgcgctctca attggcctct ctgtaccggg attatggctg
    44521 taccgcaaac gcccccgcgt gtgatcggtg gaacgcctcc tgctgttctt acaggtctgt
    44581 gtggtactat aaaaacagtc gcccttctcg gttgttgttc catattgaga aacattatgt
    44641 cttccagaat tttaacgtcg gacgtcatcg gtattgacgt ccttttacac gatcatcatg
    44701 ctgtgctggc gaagtcaacg ggcggcgcag tggcggtatt cgctaataat gcgcctgcct
    44761 tttatgccgt gacgcctgca cgcatggctg aactgctggc gcttgaagaa aagttatcac
    44821 gtccgggaag cgatgtggcg ttagacgcgc aattttacga agaacccgaa gccgcccccg
    44881 ttgcgattcc ctgcggaaaa ttcgccatgt atcccgcctg gcaaccggat gcggattttc
    44941 agcgtcaggc tgccctttgg ggcgtggcgc ttcgggagcc tgtcaccgca gaagagctag
    45001 cggcgtttat cgcctactgg caggcggaag gtaaggtttt tcaccatatc cagtggcagc
    45061 aaaagctggc gcgcagcgtg caaatcagcc gttccagcaa tggcggaatg ccgcagcgcg
    45121 acatcaatag cgtcagcgaa cctgacaatc atattccacc aggttttagg gggtaacgat
    45181 gaaaaatgtt ggcgacctga tgcagcgtct acaaaaaatg atgcctgcgc atattacgcc
    45241 ggcgtttaaa acgggcgaag aactgctggc ctggcagaaa gagcagggcg agatccgggc
    45301 ggcagcgctg gcgcgggaaa atcgggcgat gaaaatgcag cgcaccttta accgttccgg
    45361 cattcgaccg ctgcatcaaa actgctcgtt tgataactat cgggttgagt gcgacggaca
    45421 aatgaacgcg ttaagcaaag cccgacagta cgtggatgaa tttgacggca atatcgccag
    45481 ctttgtcttt tccggcaagc cgggaaccgg taaaaaccat ctcgccgcgg ctatttgtaa
    45541 cgagctgctg ctgcgcggaa agtcggtact gattatcacc gtagcggata ttatgtcagc
    45601 gatgaaagac acgttcagca atcgggaaac cagcgaagag cagttgctta acgatctgag
    45661 taacgttgat ctgctggtga tcgacgagat cggcgtgcag accgaatccc gctatgaaaa
    45721 agtgatcatc aatcaaattg tcgatcgtcg ttcctcgtca aaacgtccca ccggcatgtt
    45781 gacgaacagc aatatggaag agatgacgaa aatgcttggc gaacgcgtca tggaccgtat
    45841 gcgtctcggc aacagtttat gggttaattt tagctgggac agttaccgca gccgagtgac
    45901 gggtaaagag tattaaattg caacgtgcgc cagggcgata cgacgcctag ctggcataac
    45961 acaggtgatt accatgaata cagcgaaaca tgttctgtgc tgcgcggcga tcgccagcgt
    46021 actgatttcc accagcggta ttgccgccag tcagttaagc gctcagggcg cgaacgcaca
    46081 gcagggcggg atgtcgcttt ctgcgctaac cggtctgctc agcagaggtg cccagtcgct
    46141 cagcgctgat aatatgaata atgccgccgg tattttgcag tactgcgcca aacagaaact
    46201 ggcgtccgct accaacgtgg aaaacgttaa aaatcagatt ctgaacaagt tagggttgga
    46261 taccacacag caggagcagg acactaacta cctgaacggc ctgcaagggt tgctcaagac
    46321 gaaggacggc cagcaattga acctcaataa tatcggcagt acgccgctgg cggaaaaggt
    46381 gaaaaccaaa gcttgcgatc tggtgttgca gcaagggctg aatttcctct cctgactgcg
    46441 cttttctgac cgtgcgccac gccgggacgc cctgttaaaa gccgtgtttt ggccctttac
    46501 ccgccaacac ggcattaacc cgacttttct cttcgtcttt tcctgttatt aaccgctatg
    46561 gcaggaagtg atgccgatca aaaaaccaac tttctaaact cattctaaat aacagcgccg
    46621 tgtaaagtta ttagaattgc agcaatgtga catcgctatt acattgttag aaattttttc
    46681 ctgccagcga taagcctggt ttattgagga tcgtcagttg tccgagttgc tctctgtcgc
    46741 tctgtttctc gcctctgtgc tgatatatgc ctggaaggcg ggccgtaaca cttggtggtt
    46801 tgccgccact ctcacggtgc tgggactttt tgtcattctg aatattaccc tgtatgccag
    46861 cgactatttt accggcgacg ggatcaacga cgcagtgctt tatacgctca cgaatagtct
    46921 gacgggagcg ggagtcggca aatatattct gccgggaatc ggcattgccc tggcgttagt
    46981 ggcggtattc ggcgcgctgg gatgggtact acgccgccgc cgtcaccatc ctcatcatgt
    47041 cggttacagc ctgctggcgt tactgctggc gttgggttcg gtcgacgcca gcccggcgtt
    47101 tcgccagatt accgaactgg taaaatcaca aatgcgcgat ggcgatccgg attttgccgt
    47161 ttattataaa gaaccagcaa aaaccattcc tcatccgaag ctcaatctgg tctatatcta
    47221 cggcgagagc ctggaacgga cctattttga taatgacgcg ttccccaatc tcacgccaga
    47281 gttgggcgcg ctgaaaaatg aggggctgga tttcagccat accatgcaac tgccgggaac
    47341 ggattacacc atcgccggga tggtggcttc ccagtgtggt attccgctgt ttgcgccgtt
    47401 tgagggcaat gcgtccgcgt cggtttccag cttcttcccg cagaatatct gcctcggcga
    47461 tattctgaaa aactccggct accagaacta tttcgtgcag ggcgctaacc tgcgttttgc
    47521 cgggaaagac gtgttcctga aatcacacgg atttgatcat ctgtacggcg ctgaagagct
    47581 aaaaacggtg gtggcggacc cgtcttatcg taacgactgg ggcttctacg acgatacggt
    47641 gcttgatgag gcatggaaga aatttgaagc gctttcccgc tcaggccagc gtttttcgct
    47701 gtttacgctg accgtagata ctcaccaccc ggacgggttt atctcacgca cctgcaaccg
    47761 taaacgctac gattacgacg gcaagcccaa ccagtccttt agcaccgtaa gttgcagcca
    47821 ggaaaacatc gccgagttta tcaacaaaat caaagcgtca ccgtggttta aagataccgt
    47881 tatcgtcgtc tcttccgacc atctggcgat gaacaatacg gcctggaaat acctgaataa
    47941 gcaagatcgc aacaatctgt ttttcattct gcgcggcgat aaaccgcagc aggagacgct
    48001 ggcggtcaaa cgcaacacga tggacaacgg cgcaacggtg ctggatattc tcggcggcga
    48061 taattttatc ggtctgggac gtagcagcct ttccgggcag tcgctgtcgg aagtgttcct
    48121 gaatgtaaaa gagaaagtgc tggcgatgaa gccggatatc attcgcctgt ggaatttccc
    48181 gaaagagata aaagatttta ccgtcgatcg ggacaaaaac atgatcgcgt tttccgggag
    48241 ccacttccgc ctgccgttac tactgcgcgt atcggataag cgcgtcgagc cgttaccgga
    48301 aagtgaatac tccgctccgc tacggttcca gttggccgac ttcgccccgc gcgataattt
    48361 cgtttggatc gatcgctgct acaaaatggc gcagctatgg gcgccggcgc tggcgctctc
    48421 taccgactgg tgcgtctcgc agggacagct tggcgggcag caaaccgtac agcatgttga
    48481 taaagcgcag tggcagggta agacggcgtt taaagacacg atgatcgata tggagcgcta
    48541 caaaggcaac gtcgatacct taaagattgt cgataacgat attcgttata aagccgatag
    48601 ctttattttt aatgtggcgg gcgcgccgga ggaggtgaag cagtttagcg gcatttcccg
    48661 gccggagtcc tgggggcgct ggtcaaatgc gcagttgggc gatgaggtta aaatcgaata
    48721 taaagcgccg ctgccgaaaa agtttgatct ggtgatcacc gccaaagcct tcggcgacaa
    48781 cgcgaatcgg ccgattccgg tacgcgtagg caacgaagaa cagacgctgg tgctgggtca
    48841 cgatgtgtcc actatcacgc tgcatttcaa caacccgacg gacgcgaata ccttagtcat
    48901 tgcgccgccc gctcccgtct ccaccaacga aggtaatatt ttgggccatt cgccgcgcaa
    48961 attggggatt ggcatggtgg agatcaaagt ggtgaatgtt gagagttaaa agagaatgtc
    49021 atatatgccg ggtgcggcta cgccttaccc ggcctacaca tcatctttat caataaactg
    49081 gcgcataggc ctggtaagcg ctacgccatc aggcaaaagt gtgaacatct catccggcct
    49141 acggtcgtct gtaggccgac tgttcaccac tacgccctta aaacgtttcc caattatcgc
    49201 tgccgtcggc cacagcggcc tttggtgacg acacggctgc cggggttttt accgctgcca
    49261 cttcacgcgc acgctgctgt tgctggtgaa tacggaacac cgcgacggcc tgggtcagac
    49321 ggctggcttg ctcttccagc gccgcagccg cggcggcgga ctcttccacc agcgaggcgt
    49381 tctgctgcgt tacgcgatcc atctccgcta ccgccaggcc cacctggtcg ataccacggc
    49441 tttgctcgtc agacgccgag gcaatctcgc ccataatgtc ggtcacgcgg gtaactgcat
    49501 tgacgatctc atccatggtt tcaccggcgc tttcgaccag cgtcgaacct acatcaacac
    49561 ggctcacgga atcctcaatc agactcttga tctcccgtgc cgcctgcgcg ctacgctggg
    49621 ccagattacg gacttcaccg gccaccaccg cgaacccgcg tccctgctcg cctgcgcgcg
    49681 ccgcttctac cgccgcattc agcgccagaa tattggtctg gaaagcaata ccgtcgatta
    49741 cgctgataat atcggcgatt ttctgcgaac tggaggcgat atcgcgcatt gtttgtacga
    49801 cgttatccac tactttgccg cctttttgcg ctgtctctga cgcactcagc gccagatggc
    49861 tggcctgacg ggcgttttcg gcgttctgtt tcacggtggc ggtcagttgt tccatactgg
    49921 cggcggtctc ttccagagac gctgcctgct gctcagtacg ggaagagaga tcgttgttgc
    49981 ccatcgcaat ctcgctggcg ccgctataga ttgcattcgc gccgttacgt acatcgccaa
    50041 cggtacgcat cagttcactt tgcatatgac gcaggttttc agccaactgc cccatttcgt
    50101 tggagccttc cacgtcgata cgcttcacca gatcgccgct ggcgatatga cgaatgcttt
    50161 caatcagacg attcatcggg gcgataagcg acagtttgat gccgaaccag acggcgataa
    50221 tgaccaccag aacggcaatc agcacactga ccagtaccca catcgcctgg ttgtaggaac
    50281 tgttgttatc ctcaacagca atatcgtaca gacgatcgtt ttgctgcata taggccatgt
    50341 actgcttctc aaaagcgtcc tgatagcttt gagtcggttg atcaaaaact cgttaatctt
    50401 acccgcgcca agaagctgaa taagctccgc caacgcgtcg tggtagatat cataggttcg
    50461 tttgatctca aggaaagccg cctcactctg acgtggatcg cgcggtaacg cctcatactg
    50521 cgcccagttt ttttcggtca gcttcagcgt attggtcgcc ccctgcatca gttcagcgac
    50581 agttgcgccg ctgccaatat tgctctggtc catcatccag cggatacccg cgcgattcag
    50641 ggtattacgc gtttgcaaca gttccaccca gattgcattc agggcagact gctgctgacg
    50701 aatggtttgc aatacggtga agttttcttt gtcattcttc agcgagttga agaacagccc
    50761 gccggatgtc agttgtaaaa ggccaaatag cgccaatacc agcagtaagc tggtaacaat
    50821 tttaattcgc tttaacatgt tttctctttc cgctagacag atacagaatt ttcggcctgg
    50881 aaagggaaaa ctttatggga tgcgcgccat taatatcacg attagctcag tgaagtcgtt
    50941 atgacgcccc gcgcaacaag gatcgtccca ttttatatcg tgatctcaat cacataaaat
    51001 agcccacgcc ctcctccgcg aaaccgctta ccggtacgtc cgaccgctta aaccgccata
    51061 caaccactca ctgatttacc taactttacg cgcgcgatga tctggcaaga tcctctcagc
    51121 atagcagtca atctacctcc tcaaacacga actcaatgtc cacccagctt cggctgataa
    51181 ttaaacttac aaccaggttt tactatggat acgaaaaaga tattcaagca cataccctgg
    51241 gtgattctcg gaatcatcgg tgctttctgc ctctcggtcg ttgccctacg tcggggtgaa
    51301 cacgtgagcg ccctgtggat cgtggtcgct tccgtttccg tctatctggt ggcttaccgc
    51361 tactacagcc tgtacatcgc ccagaaggtc atgaaactcg acccgacgcg cgcgacgccg
    51421 gcggttatca ataacgacgg cctgaactac gtgccgacta accgctacgt gctgtttggt
    51481 caccacttcg ccgccatcgc cggcgcaggt ccgctggtcg ggccggtatt ggccgcgcag
    51541 atgggctatc tgccggggac actgtggctg ctggcgggcg tagtgctcgc gggcgcagtg
    51601 caggacttta tggtgctgtt catctcttcc cgccgtaacg gcgcctctct tggcgagatg
    51661 atcaaagaag agatggggac cgttccaggc accatcgcgc tattcggctg cttcttaatc
    51721 atgatcatca tcctcgcggt gctggcatta attgtggtta aagcgctggc cgaaagcccg
    51781 tggggcgtct tcactgtctg ctcaacggtg ccgattgcgc tgtttatggg catctacatg
    51841 cgcttcctgc gtccgggacg cgtaggcgaa gtctccgtta ttggtatcgt gctgctggtg
    51901 gcgtctattt acttcggcgg cgtaattgcc cacgacccgt actggggccc ggcgctgacc
    51961 tttaaagaca ccaccattac cttcgcgctg atcggctacg cctttgtttc cgcgctgctg
    52021 ccggtatggc tgatcctcgc cccgcgcgac tatctcgcta ccttcctgaa aatcggcgtg
    52081 atcgtcggtc tggcgctggg gattgtgatc ctcaacccgg aactgaaaat gccagcattg
    52141 acgcagtatg tcgacggtac cggcccgctg tggaaaggcg ctctgttccc gttcctgttc
    52201 atcaccatcg cctgtggcgc cgtctctggc ttccacgcgc tcatctcttc cggcaccaca
    52261 ccgaaactgc tggcctgtga gaccgatgcg cgttttatcg gctacggcgc gatgctgatg
    52321 gagtcctttg ttgcggtgat ggcgctggtg gcggcctcga tcattgaacc gggtctctac
    52381 ttcgcgatga acaccccgcc ggcaggtctg ggcattacca tgccaaacct gcacgagatg
    52441 ggcggcgaga acgcgccgct gattatggcg cagttgaaag acgttactgc acatgcagcg
    52501 gcgaccgtca gctcctgggg ctttgtgatt tccccggaac aaatcctgca aactgcgaaa
    52561 gatatcggtg aaccgtcagt attgaaccgc gcaggcggcg cgccaacgct ggcagtaggt
    52621 atcgcgcacg tgttccacaa agtcctgccg atggcggata tgggcttctg gtatcacttc
    52681 ggtattctgt tcgaagcact gtttatcctg accgcactgg atgcgggtac ccgttccggc
    52741 cgctttatgt tgcaggattt gctgggtaac ttcgtcccgt tcctgaaaaa aaccgattct
    52801 ctggtcgcgg gtatcatcgg taccgcaggc tgcgtcggtt tgtggggcta tctgctgtat
    52861 cagggtgtgg tcgacccgct gggcggcgtg aagagcctgt ggccgctctt cggtatctct
    52921 aaccagatgc tggccgccgt ggcgctggtg ttgagcaccg tggtactgat caaaatgcag
    52981 cgcaccaagt acatctgggt gacggtaatc ccggcggtat ggctgctgat ctgcaccacc
    53041 tgggcactgg gcctgaaact gttcagcgcc aacccacaga tggaaggttt cttctacatg
    53101 gcaaacctgt ataaagagaa gattgccaac ggcaccaacc tgaccgcgca gcagattgcc
    53161 aatatgaacc atatcgtggt gaacaactac actaacgctg gtttgagtat tctgttcctg
    53221 gtggtggtgt acagtattat cttctacggt ttcaccacct ggatgaaggt acgcaacagc
    53281 gataaacgta ccgataaaga aaccccgtat gtgcccgtgc cggaaggcgg cgtgaagatc
    53341 tcttcacacc actaaaactg atgccgggta gcgcacagcg atcccggcta gtgtaggccg
    53401 gataaggcgc aagccgccat ccggctttat tcattaacag gacggcagaa tgtttgatac
    53461 tttaggtcag gcaaaaaaat atctcggcca ggcggcaaaa atgttgattg gtattccgga
    53521 ctacgacaac tatgtcgagc acatgaaaac caaccatccc gacaagccgt acatgaccta
    53581 tgaagagttc ttccgcgaac gtcagcaagc acgttacggc ggcgatggca aaggcggtat
    53641 gcgctgttgt taatggagag actatgaccc cgattgcagt taccctactt accggttttc
    53701 ttggtgccgg caaaaccacc ctactacgcc atatcctcaa cgaacaacat ggttttaaaa
    53761 tcgccgttat cgaaaacgaa tttggcgaag tctccgttga cgatcaactg attggcgatc
    53821 gcgccacaca gatcaaaacc ctgactaacg gctgcatctg ctgtacccgc tccaacgagc
    53881 tggaagatgc gctattagac ctgctcgaca gccgcgaccg cggcgatatt gctttcgacc
    53941 gcctggtgat tgaatgcacc ggcatggccg accccggccc gattattcag acctttttct
    54001 accatgacgt attatgcgaa cgctacctgt tagacggcgt gattgcgctg gtcgacgcgg
    54061 tgcacgctaa cgagcagatg aaccagttca ccatcgccca gtcgcagata ggctacgccg
    54121 accgtatcct gctgaccaaa accgacgtgg caggcgacag cgagaaactg cgcgagcggc
    54181 tggcgcgtat caacgcccgc gccccggttt acaccgtggt acacggcgat attgacctga
    54241 gtcagttgtt taataccagc ggctttatgc tggaagagaa cgtgctggca agccaaccgc
    54301 gtttccactt tattgccgat aaacagaacg atgtgtcgtc aattgtggtg gaactggatt
    54361 acccggtgga tatcagcgag gtttcgcggg tgatggaaaa cctgctgctg gaatcagcgg
    54421 ataaactgct gcgttacaaa gggatgctgt ggatcgacgg cgaacccaac cgcctgctgt
    54481 tccagggcgt gcagcgtctc tacagcgccg actgggacag accgtggggc gacgaaacgc
    54541 cgcatagcac gctagtgttt atcgggatcc agttgccgga agacgagatc agagcggcgt
    54601 ttgcggggtt aaggaagtaa ccattaagcg cttatctggc ctggcgggaa tttgtaggcc
    54661 ggataaggcg cagccgccat ccggcatctt ctggctattt cttattttgc tcgcgcagca
    54721 tcgcttcgcg cagaatggca ttcagccgcg tctggtagcc ttttcctggc cgtttcagcc
    54781 attccataac gtcggcgtca atacgcaccg aggcctgagt ttttaacggg cgaaaaaact
    54841 taccacgcac tgcttcagac cactgtccat cctccgaagc gggaatgtcg ctgtaatcaa
    54901 tctcatcatc tgattttttc gccagcgcct tcagttcagc ctcatgctga gcactcagcg
    54961 cggatgcgtt gccgcgttta tgtttaacca tgctcataac gattcctctc ttttctgtct
    55021 gccttacgag cgctgatgat acggataact tcaaaaccac tttcgaaccg aacgctatga
    55081 gcaaccagaa tgaccacaat gccatgaaca aggccgaggg tctgccaacg atattctcca
    55141 ttctcataac gctcctgacg tgacaggtgt cggggatcgt caaacaccag taccgcatcc
    55201 tcaaagcgga caccgtgctt cctcaggttg cttttagcct tgttcgcatc ccattcaaac
    55261 tccatcggca tgtgttttcc ctaa
//
LOCUS       DAJVKX010000012        54477 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000012 DAJVKX010000000
VERSION     DAJVKX010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 54477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54477
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.012"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(42..1355)
                     /gene="rfbH"
                     /locus_tag="OPY25_000697"
     CDS             complement(42..1355)
                     /gene="rfbH"
                     /locus_tag="OPY25_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein RfbH"
                     /protein_id="HCS0926387.1"
                     /translation="MTANNLREQISQLVAQYANEALSPKPFVAGASVVPPSGKVIGAK
                     ELQLMVEASLDGWLTTGRFNDAFEKKLGEFIGVPHVLTTTSGSSANLLALTALTSPKL
                     GERALKPGDEVITVAAGFPTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSK
                     AIMIAHTLGNAFNLSEVRRIADKYNLWLIEDCCDALGTTYEGRMVGTFGDIGTVSFYP
                     AHHITMGEGGAVFTKSGELKKIIESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGY
                     DHKYTYSHLGYNLKITDMQAACGLAQLERVEEFVEQRKANFSYLKQGLQSCTEFLELP
                     EATEKSDPSWFGFPITLKETSGVNRVELVKFLDEAKIGTRLLFAGNLIRQPYFANVKY
                     RVVGELTNTDRIMNQTFWIGIYPGLTTEHLDYVVSKFEEFFGLNF"
     gene            complement(1382..2461)
                     /gene="rfbG"
                     /locus_tag="OPY25_000698"
     CDS             complement(1382..2461)
                     /gene="rfbG"
                     /locus_tag="OPY25_000698"
                     /EC_number="4.2.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose 4,6-dehydratase"
                     /protein_id="HCS0926388.1"
                     /translation="MIDKNFWQGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAP
                     TVPSLFEIVRLNDLMESHIGDIRDFEKLRSSIAEFKPEIVFHMAAQPLVRLSYEQPIE
                     TYSTNVMGTVHLLEAVKQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNS
                     KGCAELVASAFRNSFFNPANYEQHGVGLASVRAGNVIGGGDWAKDRLIPDILRSFENN
                     QQVIIRNPYSIRPWQHVLEPLSGYIVVAQRLYTEGAKFSEGWNFGPRDEDAKTVEFIV
                     DKMVTLWGDDASWLLDGENHPHEAHYLKLDCSKANMQLGWHPRWGLTETLSRIVKWHK
                     AWIRGEDMLICSKREISDYMSATTR"
     gene            complement(2466..3239)
                     /gene="rfbF"
                     /locus_tag="OPY25_000699"
     CDS             complement(2466..3239)
                     /gene="rfbF"
                     /locus_tag="OPY25_000699"
                     /EC_number="2.7.7.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate cytidylyltransferase"
                     /protein_id="HCS0926389.1"
                     /translation="MKAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVH
                     GIKDFIICCGYKGYVIKEYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGD
                     SSMTGGRLKRVAEYVKDDEAFLFTYGDGVADLDIKATIDFHKAHGKKATLTATFPPGR
                     FGALDIQAGQVRSFQEKPKGDGAMINGGFFVLNPSVIDLIDNDATTWEQEPLMTLAQQ
                     GELMAFEHPGFWQPMDTLRDKVYLEGLWEKGKAPWKTWE"
     gene            complement(3255..4229)
                     /locus_tag="OPY25_000700"
     CDS             complement(3255..4229)
                     /locus_tag="OPY25_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-6-deoxy-delta-3,4-glucoseen reductase"
                     /protein_id="HCS0926390.1"
                     /translation="MSHIIKIFPSNIEFSGREDESILDAALSAGIHLEHSCKAGDCGI
                     CESDLLAGEVVDSKGNIFGQGDKILTCCCKPKTALELNAHFFPELAGQTKKIVPCKVN
                     SAVLVSGDVMTLKLRTPPTAKIGFFPGQYINLHYKGVTRSYSIANSDESNGIELHVRN
                     VPNGQMSSLIFGELQENTLMRIEGPCGTFFIRESDRPIIFLAGGTGFAPVKSMVEHLI
                     QGKCRREIYIYWGMQDSKDFYSALPQQWSEQHDNVHYIPVVSGDDAEWGGRKGFVHHA
                     VMDDFDSLEFFDIYACGSPVMIDASKKDFMMKNLSVEHFYSDAFTASK"
     gene            complement(4235..4786)
                     /gene="rfbC"
                     /locus_tag="OPY25_000701"
     CDS             complement(4235..4786)
                     /gene="rfbC"
                     /locus_tag="OPY25_000701"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCS0926391.1"
                     /translation="MMIVIKTAIPDVLILEPKVFGDERGFFFESYNQQTFEESIGRKV
                     TFVQDNHSKSKKNVLRGLHFQRGENAQGKLVRCAVGEVFDVAVDIRKESPTFGQWVGV
                     NLSAENKRQLWIPEGFAHGFVTLSDYAEFLYKATNYYSPSSEGSILWNDETIGIEWPF
                     SQLPELSAKDAAAPLLHQALLTE"
     gene            complement(4787..5665)
                     /gene="rfbA"
                     /locus_tag="OPY25_000702"
     CDS             complement(4787..5665)
                     /gene="rfbA"
                     /locus_tag="OPY25_000702"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCS0926392.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGN
                     NDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDQNGTAVSL
                     EEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSSRGELEITDINRIYMDQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKNFINAQQVIKLAGPL
                     SKNDYGKYLLKMVKGL"
     gene            complement(5713..6612)
                     /gene="rfbD"
                     /locus_tag="OPY25_000703"
     CDS             complement(5713..6612)
                     /gene="rfbD"
                     /locus_tag="OPY25_000703"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCS0926393.1"
                     /translation="MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFCGDFSNPK
                     GVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANEIGAWVVHY
                     STDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKYLIFRTSWVYAGKGN
                     NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVTLNKPEVAGLYHLVAG
                     GTTTWHDYAALVFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFG
                     LILPQWELGVKRMLTEMFTTTTI"
     gene            complement(6612..7697)
                     /gene="rfbB"
                     /locus_tag="OPY25_000704"
     CDS             complement(6612..7697)
                     /gene="rfbB"
                     /locus_tag="OPY25_000704"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCS0926394.1"
                     /translation="MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLS
                     DISESNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDL
                     LDEIVPKATSYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWY
                     LANTQWVNNVKSGAYQSWIEQNYEGRQ"
     gene            complement(8074..8967)
                     /gene="galF"
                     /locus_tag="OPY25_000705"
     CDS             complement(8074..8967)
                     /gene="galF"
                     /locus_tag="OPY25_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HCS0926395.1"
                     /translation="MMNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQAQPLGLGHSILCARPVVGDNPFIVVLPDIIIDDATADPLRYNLAAMVARFNETGRS
                     QVLAKRMKGDLSEYSVIQTKEPLDNEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLS
                     ADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKSIEQLLHE"
     gene            complement(9145..10548)
                     /gene="wcaM"
                     /locus_tag="OPY25_000706"
     CDS             complement(9145..10548)
                     /gene="wcaM"
                     /locus_tag="OPY25_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HCS0926396.1"
                     /translation="MPATKFSRRTLLTAGSALAVLPFLRALPVQAREPRQTVDIKDYP
                     ADDGIASFKQAFADGQTVVVPSGWVCENINAAITIPAGKTLRIQGAVRGNGRGRFILL
                     DGCQVVGEQGGSLHNVTLDVRGSDCVIKGVTMSGFGPVAQIFIGGKEPQVMRNLIIDD
                     ITVTHANYAILRQGFHNQMDGARITHSRFSDLQGDAIEWNVAIHDRDILISDHVIERI
                     DCTNGKINWGIGIGLAGSAYDNSYPEDQAVKNFVVANITGSDCRQLVHVENGKHFVIR
                     NVKAKNITPDFSKNAGIDNATIAIYGCDNFVIDNIDMTNSAGMLIGYGVVKGKYLSIP
                     QNFKLNAIRLDNRQVAYKLRGIQISSGNAPSFVAITNVRMTRATLELHNQPQHLFLRN
                     INVMQTSAIGPALKMHFDLRKDVRGQFMARQDTLLSLANVHAINENGQSSVDIDRINH
                     QTVNVEAVNFSLPKRGG"
     gene            complement(10559..11779)
                     /gene="wcaL"
                     /locus_tag="OPY25_000707"
     CDS             complement(10559..11779)
                     /gene="wcaL"
                     /locus_tag="OPY25_000707"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaL"
                     /protein_id="HCS0926397.1"
                     /translation="MKVSFFLLKFPLSSETFVLNQITAFIDMGHEVEIVALQKGDTQH
                     THAAWEKYGLAAKTRWLQDEPQGRLAKLRYRACKTLPGLHRAATWKALNFTRYGDESR
                     NLILSAICAQAGQPFVADVFIAHFGPAGVTAAKLRELGVLRGKIETIFHGIDISSREV
                     LSHYTPEYQQLFRRGDLMLPISDLWAGRLKSMGCPPEKIAVSRMGVDMTRFSHRPVKA
                     PGMPLEMISVARLTEKKGLHVAIEACRQLKAQGVAFRYRILGIGPWERRLRTLIEQYQ
                     LEDVIEMPGFKPSHEVKAMLDDADVFLLPSITGTDGDMEGIPVALMETMAVGIPVVST
                     VHSGIPELVEAGKSGWLVPENDAQALAARLAEFSRIDHDTLGSVIMRAREKVAQDFNQ
                     QAINRQLASLLQTI"
     gene            complement(11776..13054)
                     /gene="wcaK"
                     /locus_tag="OPY25_000708"
                     /pseudo
     CDS             complement(11776..13054)
                     /gene="wcaK"
                     /locus_tag="OPY25_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461046.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis pyruvyl transferase
                     WcaK"
     gene            complement(13076..14554)
                     /gene="wzxC"
                     /locus_tag="OPY25_000709"
     CDS             complement(13076..14554)
                     /gene="wzxC"
                     /locus_tag="OPY25_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid undecaprenyl disphosphate flippase
                     WzxC"
                     /protein_id="HCS0926398.1"
                     /translation="MSLRQKTISGVKWSAIATIVIIGLGLIQMTVLARIIDNHQFGLL
                     TVSLVIIALADTISDFGIANSIIQRKTIGHLELTTLYWLNVGLGIVVFAVVFWLSDAI
                     AHVLHNPDLAPLIKTLSLAFIVIPHGQQFRALMQKELEFNKIGMIETTSVLAGFTFTV
                     ISAHYWPLALTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVSTNLRFGAWLTA
                     DSIVNYINTNLLTLVLARILGASVAGGYNLAYNVAVVPPAKLNPIITRVLFPAFAKIQ
                     DDTEKLRVNFYKLLSVVGIINFPALLGLMVVANNFVPLVFGEKWNSIIPILKLLCVVG
                     LLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAILIGGHLAGAIGVTLGFLVVQI
                     INTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTFITSYGAGKLVDGYLPLSGVFA
                     LQVVVGILSFILMIIFSRNALVMEIKNQLVGSEKMKKLLRVG"
     gene            complement(14656..16050)
                     /gene="wcaJ"
                     /locus_tag="OPY25_000710"
     CDS             complement(14656..16050)
                     /gene="wcaJ"
                     /locus_tag="OPY25_000710"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HCS0926399.1"
                     /translation="MTNLKKRERAKTNASLISMVQRFSDITIMFGGLWFICEVSGLPF
                     LYMHLLVALITLVVFQMLGGMTDFYRSWRGVKMSTELTLLLQNWTLSLIFSAGLVAFN
                     DDFDNRLATWLAWYALSSLGLVLCRSFIRFGAGWLRNRGYNTRRGAVAGDLPAGQALL
                     DSFRNEPWLGFEVVGVYHDPKPGGVSADWAGNFEQLIDDAKASRIHNVYIAMSMSDGA
                     MVKKLVRELADTTCSVILIPDVFTFNILHSRVEEMSGVPVVPLYDTPLSGINRLLKRA
                     EDIVLASLILLLISPVLCCIAPAVKLSSPGPVIFRQTRYGMDGKPSKVWRFRSMKVME
                     NDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYR
                     QLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIV
                     FLTIFKGFVNKAAY"
     gene            complement(16104..17474)
                     /gene="cpsG"
                     /locus_tag="OPY25_000711"
                     /gene_synonym="manB"
     CDS             complement(16104..17474)
                     /gene="cpsG"
                     /locus_tag="OPY25_000711"
                     /gene_synonym="manB"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis phosphomannomutase
                     CpsG"
                     /protein_id="HCS0926400.1"
                     /translation="MTKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLG
                     GDVRLTSEVLKMALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEAGDFPPVNDATRGSYRQISMRDAYIDHLL
                     GYISVNNLTPLKLVFNAGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPKGIP
                     NPLLPECRDDTRKAVIEHGADMGIAFDGDFDRCFLFDEKGKFIEGYYIVGLLAEAFLE
                     KHPGAKIIHDPRLTWNTEAVVTAAGGTPVMSKTGHAFIKERMRTEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGQSLGELVRDRMAAFPASGEINSRLAEPAAAIAR
                     VEAHFAEEAQAVDRTDGLSMSFADWRFNLRSSNTEPVVRLNVESRGDIPLMEARTRTL
                     LALLNQ"
     gene            complement(17585..19027)
                     /gene="cpsB"
                     /locus_tag="OPY25_000712"
     CDS             complement(17585..19027)
                     /gene="cpsB"
                     /locus_tag="OPY25_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461050.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="HCS0926401.1"
                     /translation="MIMRQTKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQ
                     TTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAAL
                     AATRQHTDCDPLMLVLAADHAIANEEAFRDAVRGAMPYADAGKLVTFGIVPDLPETGY
                     GYIRRGDVVPGATDAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEE
                     LKKFRPDILAACEQAMRGVDPDLDFIRVDEEAFLACPEESIDYAVMERTADAVVMPMD
                     AGWSDVGSWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLVTTVGVKDLVVVQ
                     TKDAVLIADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRI
                     TVKPGEGLSVQMHHHRAEHWVVVAGTARVTINGEVKLLGENESIYIPLGATHCLENPG
                     KIPLDLIEVRSGSYLEEDDVVRFEDRYGRV"
     gene            complement(19024..20247)
                     /gene="wcaI"
                     /locus_tag="OPY25_000713"
     CDS             complement(19024..20247)
                     /gene="wcaI"
                     /locus_tag="OPY25_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis fucosyltransferase
                     WcaI"
                     /protein_id="HCS0926402.1"
                     /translation="MKILVYGINYSPELTGIGKYTGEMVAWMAREGHEVRVITAPPYY
                     PQWKVGERYSAWRYRREEGEATVWRCPLYVPKQPSTLKRLLHLGSFALSSFFPLMAQR
                     RWKPDRIIGVVPTLFCTPGMRLLATLSGARTVLHIQDYEVDAMLGLGMAGKGKRGSVA
                     RLATAFERSALRNVDNVSTISRSMMNKAREKGVAAEKILFFPNWSEVARFQDVNDADV
                     TALRQQLGLPEGKKIVLYSGNIGEKQGLEKVIDAAERLRDRPLIFAIVGQGGGKARLE
                     NMARERGLLNIKFLPLQPYDALPALLKMGDCHLVVQKRGAADAVLPSKLTNILAVGGN
                     AVITAEPHTELGQLCARYPGIAVCVEPESTDALVDGISQALAMPKNNTTAREYAERTL
                     NKENVLRQFIADIRG"
     gene            complement(20244..20717)
                     /locus_tag="OPY25_000714"
     CDS             complement(20244..20717)
                     /locus_tag="OPY25_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461052.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HCS0926403.1"
                     /translation="MFLRQEDFAAVVRTTPLISLDFIVENGQGEILLGQRLNRPAQGY
                     WFVPGGRVCKDETLEAAFARLTQAELGVRLPLAAGTFYGVWQHFYDDNFSSEDFSTHY
                     IVLGFRLRVAESDLRLPDAQHGSYRWLTPEQLLAGDNVHENSRAYFSPDAPAVGL"
     gene            complement(20720..21685)
                     /locus_tag="OPY25_000715"
     CDS             complement(20720..21685)
                     /locus_tag="OPY25_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HCS0926404.1"
                     /translation="MNKQRIFVAGHRGMVGSAIVRQLAQRGDVELVLRTRDELDLLDG
                     RAVQAFFAGAGIDQVYLAAAKVGGIVANNTYPADFIYENMMIESNIIHAAHLHNVNKL
                     LFLGSSCIYPKLARQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPDNSHVIPALLRRFHEAAQSHAPEVVVWGSGTPMREFLHVDDMA
                     AASIHVMELAREVWQENTAPMLSHINVGTGVDCTIRELAQTIAKVVGYQGRVVFDAAK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLAGTYQWFLENQQRFRG"
     gene            complement(21688..22809)
                     /gene="gmd"
                     /locus_tag="OPY25_000716"
     CDS             complement(21688..22809)
                     /gene="gmd"
                     /locus_tag="OPY25_000716"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HCS0926405.1"
                     /translation="MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHSCNPKFHLHYGDLTDASNLTRILQEVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGIYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVRMQWMMLQQEQPEDFVIATGVQYSVRQFVELAAAQLGIKLRF
                     EGEGINEKGIVVSVTGHDAPGVKPRDVIVAVDPCYFRPAEVETLLGDPSKAHEKLGWK
                     PEITLSEMVSEMVANDLEAAKKHSLLKSHGYEVAIALES"
     gene            complement(22833..23387)
                     /gene="wcaF"
                     /locus_tag="OPY25_000717"
     CDS             complement(22833..23387)
                     /gene="wcaF"
                     /locus_tag="OPY25_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaF"
                     /protein_id="HCS0926406.1"
                     /translation="MQDLSGFTVPKGFRGANALKVQLWWAVQATLFAGSPQILYRWRA
                     FLLRLFGAKIGKNVVIRPSVKITYPWKLTVGDYAWIGDDAVLYTLGEINIGAHAVISQ
                     KGYLCTGSHDYTSAHFDINAAPIVIGEKCWLATDVFVAPGVTIGHGTVVGARSSVFKS
                     LPANAICRGNPAVVTRQRVQKVTP"
     gene            complement(23403..24149)
                     /gene="wcaE"
                     /locus_tag="OPY25_000718"
     CDS             complement(23403..24149)
                     /gene="wcaE"
                     /locus_tag="OPY25_000718"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaE"
                     /protein_id="HCS0926407.1"
                     /translation="MFLSVVTVAFRNYEGVVKTWRSLRNLARDPGLSFEWIVVDGGSE
                     DGTREFLQKRHGEFNLRFISEKDRGIYDAMNKGIALAQGRYTLFLNSGDAFHDDAALF
                     VRQLARQKGEAMYIGDALLDFGGGHKIRRKAKPGYYIYHSLPASHQAIFFPTAALKKY
                     PYDLQYHVSSDYALAARLYKAGYPFRRINGLVSEFSMGGVSTSNNLELCQDAKNVQRK
                     ILRVPGFWAQLSYLLRLKTTGKTKARYNKV"
     gene            complement(24162..25374)
                     /gene="wcaD"
                     /locus_tag="OPY25_000719"
                     /pseudo
     CDS             complement(24162..25374)
                     /gene="wcaD"
                     /locus_tag="OPY25_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461057.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative colanic acid polymerase WcaD"
     gene            complement(25349..26566)
                     /gene="wcaC"
                     /locus_tag="OPY25_000720"
     CDS             complement(25349..26566)
                     /gene="wcaC"
                     /locus_tag="OPY25_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaC"
                     /protein_id="HCS0926408.1"
                     /translation="MNILQFNVRLAEGGAAGVALDLHLRALQKGLTSHFVYGYGKGGK
                     KSVSHHRYPQVIKQTPRGTAIANIALFRFLNRDLFGNLDNLYRTVIQTSGPLVLHFHV
                     LHSYWLNLADIVTFCEKVKAQKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKSGCQKCP
                     TLSNYPPVRVDRAHQLIDGKRQRFRDMLRLGCQFISPSQHVAEAFNSVYGAGLCRVIN
                     NGIDLATEAILAQLSPVPLNPGKPRIAIVAHDLRYDGKTDQRLVHDMMALGEKIELHT
                     FGKFSPFTGQNVVNHGFETDKRKLMSALNEMDALVFSSRVDNYPLILCEALSIGVPVI
                     ATHSEAAQEVLAKSGGQTFAATDVLRLAQRRKPEIAQAVFGATLDAFRMRSRVAYSGQ
                     QMLEEYVSFYQNL"
     gene            complement(26563..27051)
                     /gene="wcaB"
                     /locus_tag="OPY25_000721"
     CDS             complement(26563..27051)
                     /gene="wcaB"
                     /locus_tag="OPY25_000721"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaB"
                     /protein_id="HCS0926409.1"
                     /translation="MLEDLRANSWSLRPCCMVLAYRIAHFCSVWRKKNVLNNLWAAPV
                     LVLYRVITECLFGYEIQAAATIGRRFTIHHGYAVVINKHVVAGDDFTIRHGVTIGNRG
                     ADSLACPVIGHGVELGANVILLGDITIGNHVTIGAGSVVLDSIPDHALVVGEKARVKV
                     ST"
     gene            complement(27054..27896)
                     /gene="wcaA"
                     /locus_tag="OPY25_000722"
     CDS             complement(27054..27896)
                     /gene="wcaA"
                     /locus_tag="OPY25_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaA"
                     /protein_id="HCS0926410.1"
                     /translation="MTTDNPLISIYMPTWNRQQLAIRAIKSVLRQDYRHWEMIIVDDC
                     SSSYQQLQQFVEELNDPRVRYTHNAMNTGACAVRNQAIMQAQGHYITGIDDDDEWTPN
                     RLSVFLAHKHQLTTHAFLYANDYVCEGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQ
                     VFTWAWRFKACLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSS
                     PKKFSGYFHFYRKHKDKFDRASKKYQLFTLYQIRNKRMTWRTLLTLLSVRNSKRLAAG
                     LRGR"
     gene            complement(27983..30142)
                     /gene="wzc"
                     /locus_tag="OPY25_000723"
     CDS             complement(27983..30142)
                     /gene="wzc"
                     /locus_tag="OPY25_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="HCS0926411.1"
                     /translation="MTEKVKQSAAVTGSDEIDIGRLVGTVIEARWWVLGTTAIFALCA
                     VIYTFFATPIYSADALVQIEQNAGNSLVQDINSALANKPPASDAEIQLIRSRLVLGKT
                     VDDLDLDIAVTKNTFPLFGAGWERLMGRHNEMVKVTTFTRPETMSGQIFTLKVLGDKR
                     YQLVSDGGFSAQGVVGQPLNKDGVTMRVEAIDARPDTEFTVSKFSTLGMINNLQNNLT
                     VTETGKDTGVLNLTFTGEDRDQIRDILNSITRNYLQQDIAWKSEEAGKSLAFLAKQLP
                     EVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLFT
                     KAHPAYRTLLEKRKGLEDKKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQ
                     QELKITEASTVGNVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNR
                     GIESPQALEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIEA
                     IRSLRTSLHFAMMQAQNNVLMLTGVSSSIGKTFVCANLAAVISQTHKRVLLIDCDMRK
                     GYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERF
                     GELIAWASSRYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRF
                     DQNGIQVKGVILNSIFRRATGYQDYGYYEYEYQSDSK"
     gene            complement(30139..30588)
                     /gene="wzb"
                     /locus_tag="OPY25_000724"
     CDS             complement(30139..30588)
                     /gene="wzb"
                     /locus_tag="OPY25_000724"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase Wzb"
                     /protein_id="HCS0926412.1"
                     /translation="MFNKILVVCVGNVCRSPTAERLLKRFHPSLTVASAGLGALVGKG
                     ADPAAASVASAHDLSLENHCARQISARLCREYDLILTMEKRHIAALCDIAPEMRSKVM
                     LFGHWDSEREIPDPYRKSRDAFEAVYTLLERSARQWAQALNAEQGKP"
     gene            complement(30594..31733)
                     /locus_tag="OPY25_000725"
     CDS             complement(30594..31733)
                     /locus_tag="OPY25_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HCS0926413.1"
                     /translation="MMKSKMKLMPLLASLSLISGCTVLPGSNMSTMGKDVIKQQDADF
                     DLDRMVNVYPLTPRLVEQLRPRPNVAQPNMSLDQEIASYQYRVGPGDVLNVTVWDHPE
                     LTTPAGQYRSSSDTGNWAQPDGTMFYPYIGKVSVVGKTLSEIRSDITGRLAKYIADPQ
                     VDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTVLDAINAAGGLTDMADWRNVVLTHN
                     GKEQRISLQALMQNGDLSQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSSM
                     TLTEALGNAEGIDLTTSNASGIFVIRPLKGEGGRGGKIANIYQLDMSDATSLVMATEF
                     RLQPYDVVYVTTAPVARWNRLINQLLPTISGVRYMTDTASDIHSW"
     gene            32407..33987
                     /locus_tag="OPY25_000726"
     CDS             32407..33987
                     /locus_tag="OPY25_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HCS0926414.1"
                     /translation="MEWIADPSIWAGLVTLIVIELVLGIDNLVFIAILAEKLPPGQRD
                     RARITGLILAMIMRLLLLASISWLVTLTKPLFSVQALSFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSANPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
                     VIIAISLMLLASKSLTRFVNNHPTIVILCLSFLLMIGFSLVAEGFGFHIPKGYLYAAI
                     GFSVMIEALNQLAIFNRRRFLSANHTLRQRTTEAVMRLISGKKEDAELDAETAAMLAD
                     HDDSQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEAEIRALLEKNQHT
                     RLVVTGENEQEDLLGVVHVIDLLQQSLRGEPLNLRALIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQKNPDSSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPQTGEEVQVGDYLLKTLQVESHR
                     VQKVQLIPLHNGEPDQEM"
     gene            complement(34073..35929)
                     /gene="asmA"
                     /locus_tag="OPY25_000727"
     CDS             complement(34073..35929)
                     /gene="asmA"
                     /locus_tag="OPY25_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HCS0926415.1"
                     /translation="MRRFLTTLMILLVVLVAGFSALVLLVNPNDFRAYMVQQVAARSE
                     YQLQLDGPLRWHVWPQLSILSGRMTLTARGASEPLVRADNMRLDVALWPLLSHQLHVK
                     QVMLKGGVIQLTPQTEAVRSDDAPVAPKDNTLPDVAEDRGWSFDIRSLRVAGSVLVFQ
                     HENDDQVTVRDIRLNMEQDAEHRGTFDFSGRVNRDQRDLALSFSGTVDASDYPHNLTA
                     GIEQLRWQLQGADLPAQGIEGQGQLQAQWQEAQKRLSFNHLNLTANDSSLTGHVQVTL
                     AEQPEWQIDLRSSKLNLDNLLPHHSAVAQTGGAVSQGQNTLPLTRPVIASRVGAPPYQ
                     GLQSFTAEIALQADSVRWRGMDFTQVSTKMSNQTGLLDITELQGKLADGEMSLPGTLD
                     ARTASPRIEFHPRLNHVEIGTILKAFNYPISLTGKMSLVGDFSGADIDAEAFRHSWKG
                     KAHVDMSNTRLEGMNFQQLVQQAVERSGGDAQQSQENMDNATRLDRFTTDLTLNKGTL
                     TLDDMVGQSSMLALTGSGTLDLVKQSCDTQFNLRVLGGWNGDSNLITFLKETPVPLRV
                     YGKWQELNYTLQVEQLLRKHLQDEAKRRLNDWADRNKDTRNGKDVKKLLNKL"
     gene            complement(35968..36549)
                     /gene="dcd"
                     /locus_tag="OPY25_000728"
     CDS             complement(35968..36549)
                     /gene="dcd"
                     /locus_tag="OPY25_000728"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HCS0926416.1"
                     /translation="MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD"
     gene            complement(36640..37281)
                     /gene="udk"
                     /locus_tag="OPY25_000729"
     CDS             complement(36640..37281)
                     /gene="udk"
                     /locus_tag="OPY25_000729"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCS0926417.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTR
                     MQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            37612..40602
                     /locus_tag="OPY25_000730"
     CDS             37612..40602
                     /locus_tag="OPY25_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MASE1 domain-containing protein"
                     /protein_id="HCS0926418.1"
                     /translation="MSKPSQHVFVTVPHPLLRLVSLGLVAFVFTLFSLVLSRVGTQLA
                     PLWFPTSIMMVAFYRHAGRLWPGIAVACSLGSIGASLTLFPAASLNFSWTAINIIEAA
                     TGAILLRKLLPSYNPLQNLNDWFRLAIGSAVIPPLLGGLLFWLIAPEAVASKAFLIWV
                     LSEAIGALTLVPLGLLFKPHYLLRHRDPHLLLETLLTLVITLALSWLAMRYIPWPFTC
                     VIVLLMWSAVRLPRMEAFLIFLATVIVVSLMLANDPTLLATPKTDVMVNMPWLPFLMI
                     LLPANMMTMVMYAFRTERKHITESESRFRNAMEYSAIGMALVGTEGQWLQVNKSLSHF
                     LGYSQDELRTMTFQQLTWPEDLNNDLEQLNMLVRGDINSYSMEKRYYTRNGDVVWALL
                     AVSLVRHKDNQPLYFIAQIEDINDLKQSEQENQRLMERITQANEALFQEKERLHITLD
                     SIGEAVVCIDVAMNITFMNPIAEKMSGWRQEDALGAPLLTVLRITSGNKGPLLEDIYR
                     ANRSRSDMEQEIVLHCHNGGSYDIHYSITPLSTLDGDKIGSVLVIQDVTESRKMLRQL
                     SYSATHDALTQLANRASFEKQLQQRLQTIQESPQHHALVFIDLDRFKAVNDSAGHAAG
                     DALLRELASLMLSMLRSGDLLARLGGDEFGLLLPDCNSDSARFIATRLINAVNEYHFM
                     WEGRLHRIGASAGITMINEHNCQLTEVVSQADIACYAAKNSGRGRLTVYEPQHALTSS
                     KGMMPLEEQWHMIKNNLLLMLARNVAPPRTPEATSFWLVSLRLWTSEGEVMEERAFRA
                     GLADSALHHALDRRVFHEFFRHAATAVASKGLSVALPLSAAGLYSATLIDELLEQLEH
                     SPLPPRLLHLIIPADVIVKQAQTAAATLRKLRQRGCQVILSHVGRDLQLFNLLPPHIV
                     DYLLLDSDLIANVHESLMDEMLTSIIQGHAQHLDIKTLAGPVQNPQVLDTLSRIGVDL
                     IYGDTIAEAQPLDLLLNTSYFAIH"
     gene            complement(40570..41439)
                     /gene="alkA"
                     /locus_tag="OPY25_000731"
     CDS             complement(40570..41439)
                     /gene="alkA"
                     /locus_tag="OPY25_000731"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HCS0926419.1"
                     /translation="MFTLSWQPPYDWSWMLGFLAARAVDGVETVGEGFYARSLVVGEH
                     RGLVSVRPHLPTHTVQVSVSAGLLPVAPACLAKVSRLFDLDCQPEQVAAVLGPLGEDR
                     PGLRLPGSVDTFEQGVRAILGQLVSVAMAARLTAKVARRYGEALPDAPDYVCFPGPET
                     LALADPLALKALGMPLRRAEALIHLAQATLAGKLALSAPPDIEQSVKNLQTFPGIGRW
                     TANYFALRGWQAKDIFLPDDYLIKQRFAGMTAAQIRRYAERWKPWRSYALLHIWYTHG
                     WQPSMDSEIAGIQ"
     gene            41573..42925
                     /gene="yegD"
                     /locus_tag="OPY25_000732"
     CDS             41573..42925
                     /gene="yegD"
                     /locus_tag="OPY25_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCS0926420.1"
                     /translation="MFIGFDYGTANCSVAIMRDGHPQLLTMENNSALLPSMLCAPTRE
                     AVSEWLYRHHDVPATDEETQALLRRAIRYNREEDIEVGAQSVQFGLASLAHYIDDPQE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMVHILHTAHSQLPEAITQAVIGRPINF
                     QGLGGDDANRQAQGILERAAKRAGFQEVVFQYEPVAAGLDYEATLREEKRVLVVDIGG
                     GTTDCSMLLMGPQWRQRADRENSLLGHSGCRVGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPVLPWWNAVAINDVPAQSDFYSSANGRLLNDLVRNAREADKVALLLKVWRQRLS
                     YRLVRCAEESKIALSGQADVTARLPFISDDLAVAISQQGLEAALDQPLARILEQVQLA
                     LDSAQEKPDVIYLTGGSARSPLIKKALSEQLPGIPVAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            complement(43024..43137)
                     /locus_tag="OPY25_000733"
     CDS             complement(43024..43137)
                     /locus_tag="OPY25_000733"
                     /inference="COORDINATES: protein motif:HMM:NF025322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HCS0926421.1"
                     /translation="MLKRESPSRGRGQNKERVMMKVVIIMVILLVISLPAY"
     gene            43366..44607
                     /gene="mdtA"
                     /locus_tag="OPY25_000734"
     CDS             43366..44607
                     /gene="mdtA"
                     /locus_tag="OPY25_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HCS0926422.1"
                     /translation="MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAQH
                     TAAAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHF
                     QEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
                     RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISS
                     SDTAGIVVITQTHPIDLIFTLPESDIATVVQAQKAGKTLVVEAWDRTNSHKLSEGVLL
                     SLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEG
                     HFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEP
                     QTTMADEKSPSRHEGQKGARA"
     gene            44607..47729
                     /gene="mdtB"
                     /locus_tag="OPY25_000735"
     CDS             44607..47729
                     /gene="mdtB"
                     /locus_tag="OPY25_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HCS0926423.1"
                     /translation="MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVA
                     ALPEVDYPTIQVVTLYPGASPDVMTSSVTAPLERQFGQMSGLKQMSSQSSGGASVVTL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPM
                     TQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPERAVTLSANDQMQSADEYRKLIIAYQNGAPVRLGDVATVEQGAE
                     NSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSRQSLRKQN
                     RFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSVMLWITIPKGFFPVQD
                     NGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQ
                     INLKPLDARDDRVQQVISRLQTAVATIPGVALYLQPTQDLTIDTQVSRTQYQFTLQAT
                     TLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVPLSAIARI
                     EQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGST
                     LAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGS
                     ELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVK
                     SRFPRHKEEA"
     gene            47730..50810
                     /gene="mdtC"
                     /locus_tag="OPY25_000736"
     CDS             47730..50810
                     /gene="mdtC"
                     /locus_tag="OPY25_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HCS0926424.1"
                     /translation="MRFFALFIYRPVATILIAAAITLCGILGFRLLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILEFNFDRDIN
                     GAARDVQAAINAAQSLLPGGMPSRPTYRKANPSDAPIMILTLTSESWSQGKLYDFAST
                     QLAQTIAQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDEVREAIDSANVRRPQG
                     AIEDSVHRWQIQTNDELKTAAEYQPLIIHYNNGAAVRLGDVASVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDGIRAKLPELRAMIPAAIDLQIAQDRSPTIRASLQEV
                     EETLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEARMKPLQAALQGTREVGFTVISMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLVVSLTLTPMMCGWMLKSSKPRTQPRKRGVGRLL
                     VALQQGYGTSLKWVLNHTRLVGVVFLGTVALNIWLYIAIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVNNVTGFTGGSRVNSGMMFITLKPRGERKETAQ
                     QVIDRLRVKLAKEPGAKLFLMAVQDIRVGGRQANASYQYTLLSDSLPALREWEPKIRK
                     ALSALPQLADVNSDQQDNGAEMNLIYDRDTMSRLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYSQDISALEKMFVINRDGKAIPLSYFAQWRPANAPLSVNHQGL
                     SAASTIAFNLPTGTSLSQATEAIDRTMTQLGVPSTVRGSFSGTAQVFQQTMNSQLILI
                     VAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRSGGLTPEQAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKNSKPVVEI"
     gene            50807..52219
                     /locus_tag="OPY25_000737"
     CDS             50807..52219
                     /locus_tag="OPY25_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0926425.1"
                     /translation="MTEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESP
                     LHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLV
                     LARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEY
                     ASWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSK
                     SMGISPWTLAGLAAGGAAAILLYLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATT
                     LGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNS
                     LLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIF
                     ARVPNDTQQNMVISRRKRSL"
     gene            52219..53622
                     /gene="baeS"
                     /locus_tag="OPY25_000738"
     CDS             52219..53622
                     /gene="baeS"
                     /locus_tag="OPY25_000738"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HCS0926426.1"
                     /translation="MKVWRPGITGKLFLAIFATCIVLLISMHWAVRVSFERGFIDYIK
                     HGNEQRLQMLGDALGDQYQQHGNWRFLRNNDRFVFQILRSFEHDNDRDKPGPGMPPHG
                     WRTQFWVVDQNGRVLVGPRGPVPHDGTRRPILVNGVEVGAIIASPVERLTRNTDINFD
                     MQQRRASWMIVALSTLLAALATFLLARGLLAPVKRLVEGTHRLAAGDFTTRVTPTSAD
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRQFTPE
                     SVTSLQAEVGTLTKLVDDLHQLSLSDEGALAYQKTTVDLVPQLEVAGGAFRERFTSRG
                     LTLHYALPDSMTVFGDPDRLMQLFNNLLENSLRYTDSGGGLHISAEQRDKSLFLTFAD
                     SAPGVSDEQLQKLFDRFYRTEVSRNRASGGSGLGLAICVNIVHAHNGHLHAAHSPFGG
                     VSITVELPLDRDLQREV"
     gene            53619..54341
                     /gene="baeR"
                     /locus_tag="OPY25_000739"
     CDS             53619..54341
                     /gene="baeR"
                     /locus_tag="OPY25_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HCS0926427.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGD
                     KVLPYVRQTPPDLILLDLMLPGIDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALD
                     LTPAEFRLLKTLSLEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRLV"
BASE COUNT        12677 a        15241 c        13703 g        12856 t
ORIGIN      
        1 ttttcatgaa atcatagagg ggaatccccc cccctcaaaa attagaaatt caaaccaaag
       61 aactcttcaa acttgctaac tacataatct aaatgctctg tagtcaagcc tggataaata
      121 ccaatccaga acgtttgatt cattatacgg tcggtatttg tcaactcacc cactacacga
      181 tatttcacat tagcaaaata cggttggcga atcagatttc cagcaaacag taaacgtgta
      241 ccgatttttg cttcatcaag gaatttcacc agttcgacac ggttaacacc gctagtttct
      301 ttcagggtga tagggaagcc aaaccaggat ggatctgatt tctctgttgc ttctggtaat
      361 tcgaggaatt cagtgcaaga ttgcaaacct tgtttcaaat aggaaaaatt agctttacgc
      421 tgctctacaa actcttccac gcgttctaac tgagccagac cacatgctgc ctgcatgtcc
      481 gtgattttga gattatatcc gaggtgggaa taagtatatt tgtgatcata gccttgagga
      541 agtgacccca attgctgacc aaaacgttta ccgcaggtgt tatcgcatcc tggcgcacaa
      601 taacaatccc ggccccagtc acggaacgac tcaataattt tcttcagttc acctgacttg
      661 gtgaatacag caccgccttc acccattgtg atatggtgag ccggataaaa actaacggtt
      721 ccgatgtcac caaaggtacc taccatccgg ccttcataag tcgtcccaag ggcatcacag
      781 cagtcttcaa tcaaccataa gttatattta tcggcaatcc gacgaacttc actcaggtta
      841 aatgcattac cgagtgtatg agcgatcatt atcgcttttg atttctcagt aactgcagct
      901 tcaatgagag aggcatcgat attatatgtc gggatatcaa catccacgaa taccggtatt
      961 aaaccattct ggatcgccgg gttaactgta gtcgggaagc cagcagcgac agtaataacc
     1021 tcatcaccag gtttgagagc acgctcgcct aattttgggg aagtcagcgc agtcagtgcc
     1081 agcaagtttg ccgaagagcc agatgtagtc gttaaaacat gaggaactcc aataaattcc
     1141 ccaagttttt tctcaaaggc atcattgaaa cgaccagtag ttagccatcc atcaagagac
     1201 gcctcaacca tcaattgtaa ctctttggca ccaataacct tcccggaagg aggtacaacg
     1261 cttgcacctg caacaaaagg tttcgggctc aatgcctcat tcgcatactg agcgacaagc
     1321 tgagagattt gctcacgcag gttatttgct gtcattactt tgattcctta aacttatttt
     1381 cttaacgagt agttgcagac atatagtcgc tgatttcacg ctttgaacaa atcaacatat
     1441 cttcgccgcg aatccatgct ttatgccatt ttacgatgcg actaagtgtt tcagtcaatc
     1501 cccaacgcgg atgccatcct aattgcatat ttgctttaga gcaatccagt ttcaggtaat
     1561 gtgcctcatg aggatgattc tcaccatcca gtaaccagct tgcatcatca ccccaaagcg
     1621 taaccatctt gtcaacaata aattcgaccg tcttcgcatc ttcatcacgc gggccgaaat
     1681 tccatccttc agaaaactta gcaccttctg tatacaagcg ttgcgccacc acaatgtaac
     1741 cagaaagagg ctccagtaca tgctgccagg gacggataga atatgggttt cgaataataa
     1801 cctgctggtt attttcaaat gagcgcagaa tatcgggaat taaacggtct ttagcccaat
     1861 cgcctccacc tatgacatta ccagccctca cagacgccaa accaacgcca tgttgctcat
     1921 aatttgcagg attgaagaat gagttccgga atgcagacgc gactaattct gcacaacctt
     1981 tactattaga gtatggatcg taccctccca tgggttcgtt ctcacgatag ccccacaccc
     2041 actcacgatt gtcgtagcac ttatcactgg tgatatttac gactgccttt atgttaccta
     2101 cttgcttaac tgcttcaagc agatggacag tacccataac atttgttgag tatgtttcga
     2161 ttggctgttc ataagatagg cgcactaaag gctgggctgc catatggaaa acaatttctg
     2221 gcttaaattc tgcaatagaa ctgcgcagct tttcaaaatc acgaatgtcg ccaatatgag
     2281 attccataag atcattaaga cgcactatct caaataaact tggaacagtt ggcgcatcaa
     2341 gtgcatagcc ttttacaatt gcacccattt cagtcagcca tagcgaaagc cagcttcctt
     2401 taaagccagt atggccggta acgaatacac gtttaccttg ccaaaaattt ttatcaatca
     2461 tctacttact cccaggtttt ccacggagct ttaccttttt cccacagccc ttcgaggtaa
     2521 actttatcac gtagggtatc catcggctgc cagaaacctg ggtgttcaaa agccattaac
     2581 tccccctgtt gtgccaatgt cattaatggc tcttgttccc aggttgttgc atcgttatcg
     2641 atgagatcga taaccgatgg attcaacaca aagaaaccac cattgatcat tgccccatcg
     2701 cctttcggct tttcctggaa tgaccggacc tgaccagctt ggatatctaa tgcgccaaag
     2761 cgtcctggtg gaaaagtagc tgttaaggtc gctttcttac cgtgagcctt atggaaatcg
     2821 atagtcgctt tgatatcaag gtcggcaacg ccatcaccat aagtaaacag gaaagcctcg
     2881 tcatctttta cgtattcagc aacacgtttc agacgaccac cagtcattga agaatcaccc
     2941 gtatcaacca atgtgacatt ccatggttca acacgtttat ggtgaacttc catacggttt
     3001 tcagccatat ggaatgttac atctgacatg tgaaggaagt agttcgcaaa atattcttta
     3061 atcacatatc ctttataacc acagcagata ataaaatcct tgataccatg cacagaatac
     3121 attttcataa tgtgccaaag aataggcttg ccaccaattt ctaccatcgg ttttggtttt
     3181 acaattgttt cttcacttaa tctggtacca agtccaccag ccaggatgac cgctttcata
     3241 aattatcctc aatattattt agatgcggta aatgcatcag aatagaaatg ttctacagag
     3301 agatttttca tcataaagtc ctttttactg gcatcgatca tcacaggtga accacatgca
     3361 tatatatcga agaactctag agaatcaaaa tcatccatca cagcatgatg gacaaatccc
     3421 tttcttcccc cccattcggc gtcatcacca gaaacaacag ggatataatg aacgttgtcg
     3481 tgctgttcac tccactgctg cggtaatgca gagtaaaaat ctttactatc ttgcattccc
     3541 cagtagatgt agatctcacg acgacatttt ccctgaatga gatgctcaac cattgattta
     3601 actggagcga atccagtacc gcctgcaagg aagattatag gtctgtcact ttcacgaata
     3661 aaaaatgttc cgcaaggtcc ttcaatgcgc ataagagtat tttcttgtaa ctccccaaaa
     3721 atgagcgagc tcatctgacc attgggaaca ttccttacat gcaactcaat accattcgac
     3781 tcatcactat tagcgataga ataactgcga gttacacctt tataatgtaa attgatatac
     3841 tgccctggaa agaagccaat ttttgctgtt ggtggtgtgc gtaacttcaa agtcataaca
     3901 tcgcctgaaa ccagtacagc actatttacc ttgcatggga caattttttt tgtctgtcca
     3961 gctagttcag gaaaaaaatg cgcatttagc tcaagggcgg ttttaggttt acagcagcag
     4021 gttagtattt tatcaccctg tccaaaaata ttacctttgg agtcaacaac ttctcccgct
     4081 aacaaatcgg actcacagat accacaatca cccgctttgc agctatgttc aagatggatg
     4141 ccagccgata gcgcagcatc gaggattgat tcatcctctc taccggaaaa ttcaatattt
     4201 gatggaaaaa tcttaataat atgagacacg atgcttactc tgttaacaag gcttgatgca
     4261 gtaaaggtgc tgcagcatct tttgctgaaa gctcaggcag ctgagaaaaa ggccattcaa
     4321 tacctattgt ctcatcattc catagaatgc taccttccga tgaaggtgag taataattag
     4381 ttgctttgta cagaaactct gcataatcac tgagagtaac aaaaccatga gcaaaacctt
     4441 ctggaatcca aagctgtcgc ttattctcag cagatagatt tacgccaacc cactgaccaa
     4501 aagtaggtga ttcttttcgg atatcgaccg caacatcaaa aacctcaccg acagcacagc
     4561 gaactaactt tccctgtgca ttttctcctc tctgaaaatg tagccctctg agtacattct
     4621 ttttggattt tgaatgatta tcttgaacaa atgtaacttt acgtccaatc gactcttcaa
     4681 aggtctgctg gttataactt tcaaaaaaga atcccctctc atcgccaaaa actttaggct
     4741 ctaagatcaa gacatctggt attgctgttt taatcacaat catcacttat aaacctttca
     4801 ccatcttcag caaatatttg ccgtaatcat tttttgataa tggcccggcc agttttataa
     4861 cctgttgtgc atttataaaa tttttacgaa atgcgatctc ttccgggcaa gacactttca
     4921 gaccctggcg ttcttcgatg gttgcaataa aattactggc ctctatcaaa ctctgatgcg
     4981 ttcccgtatc cagccaggca taaccgcgcc ccatcatagc gacagacaat cttccctgat
     5041 ccatatagat acggttaata tccgtgattt ctaactcacc gcgagaggaa ggcttaagat
     5101 ttttcgccat ctccaccacg ctattatcat aaaaatacag ccccgttacc gcgtaattac
     5161 tcttcggttg taacggtttt tcctccagac taacggctgt gccattttgg tcaaactcaa
     5221 ccacaccgta gcgctctgga tcgtttacat gataagcgaa gacggtagca ccactttctt
     5281 tattaacggc agcttccatt aactttggta aatcatgacc atagaagata ttgtcaccca
     5341 gcactaatgc acaatcatta ttaccaatga actcttcacc aataataaac gcctgtgcta
     5401 agccatccgg acttggctgt actttatatt gaagattcag cccccattgg ctgccgtctc
     5461 ccagcagttg ttgaaaacgc ggcgtgtcct gtggcgtact gatgatcagg atatcccgaa
     5521 tgcctgccag cataagtgtg gaaaggggat agtaaatcat cggtttatca taaattggta
     5581 gcaattgctt acttaccgcc atggtcaccg gataaagacg agtgccggag cctcccgcta
     5641 aaataatgcc cttacgcgtt ttcatttcca tttctcattc atagaaaatg cccttatggg
     5701 catttaaatt tatcagatgg ttgtcgtcgt aaacatttca gtcagcatac gcttaactcc
     5761 taattcccat tgcggcagaa taaggccaaa attacgctga aacttttcag tattgagacg
     5821 cgaattacca ggtctgctcg ccggcgtcgg gtaggcgctg gtcggcacag cattaagctc
     5881 agtcagcgca agcgttatcc ctgctttgcg cgcctcgtca aagactaacg ccgcgtagtc
     5941 atgccaggtt gtagttcccc cggcaaccag atggtaaaga cctgcgactt ctggtttatt
     6001 taatgtcaca cggatcgcat gagccgtgca gtcagccagt aattccgcac cggttggcgc
     6061 accgtactga tcgttgatga ctgaaagtgt ctgacgctct ttcgccagac gaagcattgt
     6121 ctttgcgaaa ttattgccct tacctgcata aacccaactg gtgcggaaga ttaggtattt
     6181 agggcagtta tcctgcaggg ccttttctcc cgctagtttg gtcttgccat agacattcag
     6241 cggcgacgta gcgtccgttt cctgccatgg gatatcgccg gtaccaggaa atacataatc
     6301 ggttgaataa tgcactaccc atgcgccaat ttcgttggcc gctttagcga tggcttccac
     6361 actggtggcg ttaagcaact gcgccagttc tggttcagac tctgctttat ctactgcagt
     6421 atgtgctgct gcgttaacaa tcacatcggg acgaagctta cgaacggttt cggcaacgcc
     6481 tttcggatta ctaaaatcac cgcaaaactc ttttgaatgg acatccaggg caatcagatt
     6541 ccccactggc gccagagaac gttgcaactc ccagcctact tgccctgtct taccaaaaag
     6601 taagatattc attactggcg tccttcatag ttctgttcta tccaactctg atacgcccca
     6661 cttttaacat tgtttaccca ttgagtattt gcaaggtacc attccactgt tttacgaata
     6721 ccgctttcaa aggtctccag cggtttccag cctaattcac ggctaatttt acctgcatca
     6781 atggcataac gacgatcatg gcccggacga tccgcgacat aagtgatttg ttcacgataa
     6841 gaagtcgctt tgggtacaat ctcatccagc agatcacaga tggtaaatac cacatcgaga
     6901 tttttcttct cattgtggcc accaatgtta taagtctccc ctgccttgcc ttcagtcact
     6961 accatatgaa gcgcgcgagc gtgatcttct acatatagcc aatcgcgaat ctgatcccct
     7021 ttgccataaa ttggcaaagg ctttccttcc agtgcgttca aaatgaccaa cggaatcagt
     7081 ttttcaggga agtgataagg gccatagtta ttagaacaat tggtaacgat cgttggtaga
     7141 ccataggtac gccgccaggc acggactaaa tgatcgctgg atgcttttga cgcagaatag
     7201 gggctacttg gcgcatatgc cgtcgtttca gtaaataacg gcaacgtaac gctgttttca
     7261 acttcatcag gatgtggtaa atcgccgtaa acttcatcag tggaaatatg atgaaaacga
     7321 aaattatttt ttttatcttc gccaagcgca gaccagtatt tacgcgcaac ttcaagaagt
     7381 acataggtgc cgacgatatt ggtttcaata aatgctgccg gcccggtaat cgaacggtcc
     7441 acatgacttt ccgcagccaa atgcatcacc gcgtccggct ggtactgctc aaaaatacgc
     7501 gttatttcag cggaatcaca aatatccgcg tgttcaaaat tgtagcgatt actttcagaa
     7561 atatcagaaa gggattcaag attaccggcg taggttaatt tatcaatatt aactacagtg
     7621 tcctgtgtat tcttaataat atggcgaaca acagctgatc caataaaacc tgccccgcca
     7681 gtaataagta tcttcacttt tctattccat aaggcgtatt taatgtggta tttaatttgc
     7741 caataaaaat taattgctca agtcgttaca cacgctaccg cccctggttc atcagctacc
     7801 agtgcactgc gtacatatcg acttgttaca aacctcgccc agcagggcaa agctcactaa
     7861 aacttaaacg ctaattgtct tattaattgc atccggaaac aaggattaat cttataaaat
     7921 cagcattaaa atgctccaga taaccccttg ttacttaagc cctttataca aaactaaaac
     7981 ggcagtcaac actcgtttca gccaacttgc cgcttcgaat gttcactgcc gttattatgt
     8041 ttatcaccaa ccatttatca cggttgttaa tacttattca tgcagaagct gctctatgct
     8101 cttacggaac ttcgctcctt ctttcaggtt gcgcagcccg tacttcacaa atgcctgcat
     8161 gtagcccatt tttttaccgc agtcatagct gtcgcccgtc attagcatcg cgtcaaccga
     8221 ctgttttttc gccagttcag caatcgcatc ggtaagctgg atgcggcccc aggcgcccgg
     8281 ttcggttctt tccagttccg cccagatgtc ggctgaaagc acataacggc ctaccgccat
     8341 caaatcggaa tccagcgtct gcggctgatc cggtttttcg ataaactcca caatccggct
     8401 gactttgcct tcattatcca gaggttcttt cgtctggata acggaatact ccgataaatc
     8461 acctttcatg cgctttgcca gcacctggct gcgacccgtt tcattgaaac gcgccaccat
     8521 cgccgcaagg ttatagcgca gcggatcggc ggtagcatca tcaataataa tatccgggag
     8581 taccacaatg aaagggttat cgcccacaac cggacgcgcg cacagaatag agtgccccag
     8641 tcctaacggc tgcgcctggc gaacgttcat aatcgtcacg cccggtgggc agatagattg
     8701 cacttccgcc agaagctgac gcttaacgcg ctgctcaaga agcgattcaa gttcataaga
     8761 ggtgtcgaag tggttctcaa cggcattttt agacgcgtga gtcaccagca cgatttcttt
     8821 gatccctgca gccacaatct catcgacaat gtactgaatc atcggtttgt cgacgatcgg
     8881 tagcatctct tttgggattg ccttagtggc aggcaacata tgcataccca aacccgctac
     8941 cggtataact gctttcaaat tcatcattgt ttcttccacc tgtaaaatgg ttgctgaatt
     9001 atagctcttt agcttgtttt cgccagcatg aattactctg ctgccaggga taatgatggc
     9061 acgctctaca ttacgtctta gtcggcacca taacattaag tatgaacaac tttttcccag
     9121 gaattttcgt aaaaatagcg gtacttaccc tccccgcttc ggcagcgaaa aattcactgc
     9181 ttcgacattc acggtttggt gattaatcct gtcgatatcc acggaactct gcccgttttc
     9241 attgatggca tgaacattag cgagggaaag cagcgtgtcc tggcgggcca taaattgacc
     9301 acggacatct ttacgcaaat caaaatgcat ttttaacgcc gggccaatcg ctgaagtttg
     9361 catcacgttg atattacgca aaaagaggtg ctgcggttga ttatgcagtt ccagcgtagc
     9421 acgcgtcatc cgtacattgg tgatggcaac aaatgagggg gcgttaccgg aggaaatttg
     9481 aatgccgcgt aatttataag caacctggcg attatccaac cgaatagcgt ttaatttaaa
     9541 gttttgcgga attgacaggt attttccttt aacgacgcca tagccgatga gcatcccggc
     9601 actattcgtc atatcaatat tatcaatgac gaaattatca cagccataaa tggcgatcgt
     9661 tgcgttatca atacccgcat ttttactgaa atcgggcgtg atgtttttgg ctttgacatt
     9721 gcgaatgacg aaatgtttgc cattttctac gtgtaccagt tgtcggcaat cagatccggt
     9781 aatattggcc accacaaagt tttttactgc ctggtcttca ggataactat tgtcataggc
     9841 gctacccgcc agcccgatgc cgatccccca gttgattttg ccattggtac aatcaatgcg
     9901 ttcgatgaca tgatcggaaa tcaggatgtc gcggtcatga atcgcgacat tccactcaat
     9961 ggcgtccccc tgcaaatcgc taaagcgact atgcgtaatc cgcgcgccgt ccatttggtt
    10021 atgaaatccc tggcggagaa tggcgtagtt ggcgtgggta acggtgatgt catcgataat
    10081 gagattacgc atcacctgcg gttccttacc gccgatgaaa atttgcgcga cggggccaaa
    10141 gccgctcatc gtcacgcctt taatcacaca gtccgacccg cgaacatcca gcgtcacatt
    10201 gtgcagactg ccgccctgct cccccaccac ctgacacccg tccagcaaaa taaaccgtcc
    10261 ccggccattc ccacgcaccg cgccctgtat ccgcagcgtt tttcccgccg gaatcgttat
    10321 cgccgcattg atattttcac acacccatcc tgacggcacg accacagtct gcccgtcggc
    10381 gaaggcctgt ttgaacgagg cgataccgtc atccgccgga taatccttaa tatcgacggt
    10441 ctggcgaggt tcacgcgcct gtaccggcaa ggcgcgcaga aaaggaagaa cagcaagcgc
    10501 ggaacctgcc gtcaggaggg tacgtcggga gaatttagtc gcgggcatac cacctcgttt
    10561 atatggtttg tagcaggctg gctaactggc gattaatcgc ctgctgatta aaatcttgcg
    10621 ccactttttc acgagcgcgc atgatcaccg accccagcgt atcgtggtca atccggctga
    10681 actcagcgag tcgggccgcc agcgcctgcg catcgttttc cggtaccagc cagccggatt
    10741 tgccggcctc caccagttcc ggaataccgc tatgcacggt agacaccacg ggaatcccca
    10801 ccgccatcgt ctccatcagc gctaccggaa taccttccat atcgccatcc gtaccggtaa
    10861 tcgacggcag caaaaaaaca tcggcgtcat ccagcatcgc cttcacttca tggctcggtt
    10921 taaaacccgg catctcaatg acatcctcta actgatactg ctcaatgagc gtgcgcagcc
    10981 gacgttccca cgggccaatc cccagaatgc ggtagcgaaa cgccacgccc tgcgctttca
    11041 gttgccgaca ggcttcaatc gccacatgca ggcctttttt ctcggtcagg cgcgcgacgg
    11101 aaatcatctc cagcggcatc cctggcgctt tcaccggacg atgggaaaaa cgcgtcatgt
    11161 cgacgcccat gcgcgaaacg gcaatctttt ccggcggaca gcccatactt ttcaggcgac
    11221 cggcccacag atcgctgatg ggcagcatca gatcgccacg acgaaacaac tgctgatact
    11281 ccggcgtgta atgactgagc acctcgcgac tggaaatatc aattccgtgg aaaatagtct
    11341 cgattttgcc gcgaagcacg cccagttcgc gcagtttggc cgccgtcacg cccgccggac
    11401 caaagtgcgc gatgaacaca tccgccacaa aaggttggcc cgcctgcgcg caaatcgcgg
    11461 aaaggatcaa attgcgtgat tcatcgccgt agcgggtaaa attgagcgct ttccaggtcg
    11521 ccgcccgatg cagccccggc agcgttttac atgcccggta gcgcagcttc gccagccgtc
    11581 cctggggctc atcctgtaac cagcgggttt tcgccgccag gccatacttc tcccaggcgg
    11641 cgtgagtatg ttgggtatcg cctttttgta acgcgacaat ctccacctca tggcccatat
    11701 caataaacgc agtaatctga ttcagcacaa aggtttccga tgagagtgga aatttcagca
    11761 gaaaaaagct gactttcatt gcgcctcccg aattctgtcg agagcagatt tgatcatcgt
    11821 gaaccctttc gcccgctcct cggtgacggc gttagccact tttgccttta gcgcaggcaa
    11881 ttgattgagc gtatcggcca ccacgctttg taatgaaccg ttcagcaagt gacggatatc
    11941 gatggccaat tccgccaggc ctagctgctg cataatcccg gcggatttat gttcataatt
    12001 aatggcgata gcgggcgtgc caaaattcat ggagataatg gcggaatgca ggcgcgtccc
    12061 gatggtcagt acgcaggatg cgaggatctt tccgatttcc acgtcattga gttcgtccat
    12121 cgcgatatgg aaatgctctg agtcgtttac atacttcgcc atccgtaacg caaccatccg
    12181 gtcatcgcgg ttatagcgat cgatactggt gcaggtcgac agcgccagta cctgataacc
    12241 gtccgcaatc aggcgattca cgacctgggc aaatgcctgc tcataggcct gctgagtggt
    12301 gcccaggcgt ttatcaaacg gctccagatc gcgcaacgta atcgcgacgg ttttgcggcg
    12361 cgcggtgacg tccagccagt gctgcacagc ataactggcg acaaactcgt cgtgacggcg
    12421 ttcgactaac caggcggtat ccaccccctg ctctactttt cgggtatcga tctgcgcggc
    12481 ggtcatcaga tcgcggctga cggtttcacg caggatcagc gcactggtgc gcccaaaaca
    12541 taattggcga gctagttaaa gtcagggttc tggaaagggc cgacgctatg tcccaccata
    12601 taaattggtt tgttcgccat aaacgcgcac agcggatatt caaagtgagt caaaccgtat
    12661 aagtcgacat agtttgaacc gcccacctga atgacggcgt catactgcgc aataaattgc
    12721 gcgaattcgg caaattccgg cgcgatagca aaattacgca gcgatccttc ctgggcgact
    12781 ttagacaata aaattttatg ctgaaaacga cggcgtaata ctttttcacc cgaccgttaa
    12841 gccctgccgc cgcctgctgt ttctggctta attgatacag cgggtcggca ataatcggtc
    12901 gcccctgcaa ccaggaggaa ctcaccggga aacggctcat cacatccatc tccgcctctg
    12961 gcgcctgttg acggatggca tcaagcaaac cgcgcataat ggcgctatca ccacggttgc
    13021 cgcatgtgtg gttgcctaaa attaataatt tcataaatag cctcttatat cctcgtcatc
    13081 cgacacgtaa taactttttc attttttcac tgccaacaag ctgattttta atttccatca
    13141 ccagcgcatt gcgtgaaaaa ataatcatta aaataaaact caaaataccg accacaacct
    13201 gtagcgcgaa tacccctgac aacggtaaat agccgtcgac tagctttcct gcgccgtagc
    13261 tggtaataaa tgtgggcaat gagagataaa acggtagcca caggctgaga atatactgac
    13321 ggtagctgga gccgagtacc ggcttaatca tcacgaaata gctcagaatg gtgttgatga
    13381 tttgcaccac caggaacccc agcgtcacgc caatcgcccc cgccagatgg ccgccaatga
    13441 gaattgccgg gataaacaga aacgttttaa agacgttgaa cttaaagctg atatccacgc
    13501 gcgctttcgc catcagcagc gaaccaatcg ggttgccgac tgagcgcagc agccccacaa
    13561 cgcacagcaa tttcaggatc gggataatgc tgttccactt ctcaccaaac actaacggca
    13621 caaaattgtt cgccactacc atcaggccca acagcgcggg aaaattgata attcccacca
    13681 cggaaagcaa cttatagaag ttgacgcgca gcttctcggt atcgtcctgg attttggcga
    13741 atgccggaaa tagcacgcga gtaatgatgg ggttaagctt cgccggcggc acaacagcca
    13801 cgttgtacgc gaggttatat cccccggcga cgcttgcgcc gagaattctc gccagtacca
    13861 gcgtcaataa attcgtgttg atgtaattga cgatactgtc cgccgtcagc cacgcgccaa
    13921 aacgcaggtt cgtggacacc gatgccagcg aaaaatgcag ccccggacgg taaatcttgc
    13981 ggccaaagta accaaacagc agcgttcgca ccgcgctgtt caccagatag ccgagaatcg
    14041 cggttaacgc cagcggccag taatgggcgc taatcaccgt aaaggtgaac cccgccagca
    14101 cggaggtcgt ttcgatcatg ccgatcttat tgaactccag ctctttttgc atcagcgcgc
    14161 ggaactgctg cccgtgaggg atcacgatga acgccagcga caacgttttg attaacggcg
    14221 cgagatccgg gttatgcaaa acatgggcaa tcgcatcgct cagccaaaag accaccgcaa
    14281 ataccacaat cccaagccca acgtttagcc agtaaagcgt ggtcagctcc agatgcccaa
    14341 tcgttttacg ctggataatc gagttcgcga tgccaaagtc cgaaatcgtg tcggccagcg
    14401 cgataatcac cagcgatacg gtcaacaggc caaactggtg gttgtcgatg atccgcgcca
    14461 gcaccgtcat ctgaattaac cccagaccga taatcactat cgtggcgata gccgaccatt
    14521 taacgccgct gatcgttttt tgtcgtaaac tcattctttt ctccagaacc tgttcacaag
    14581 gcgtcattgg cgcagccaga ttgagcactg ccctggtgca atatggcaag taaaatagcc
    14641 ttgtgggtca ggttcttaat acgccgcttt attaacaaac cctttaaaaa tcgtcagaaa
    14701 aacgattttg atatcgaacc aaatactcca ttcgcggatg tattccaggt cgaattccac
    14761 gcgtttttcc attttctcca gcgtatcggt ctcaccgcgc cagccattaa tttgcgccca
    14821 gccggtgatg cccggcttca tcttgtggcg tagcatgtaa ccttcaatca actgacgata
    14881 ctgttcgtta tgcgccaccg cgtgcgggcg aggaccgacg atagacatcc cgccggttaa
    14941 tacgttgata aactgcggta attcatccag cgaggtacga cgcaaaaagt tacctacccg
    15001 ggtgacgcgc ggatcgtttt gcgtcgcctg ggtaacgacc ttatcgttct ccatcacctt
    15061 cattgagcgg aacctccaga ctttgctcgg cttgccgtcc atcccgtagc gcgtctgacg
    15121 gaaaatcacc ggcccgggcg agctcaattt gaccgccggc gcaatgcagc acagtaccgg
    15181 tgagatgagc agcagaatca gcgacgccag cacgatatct tctgcccgtt taagcagacg
    15241 gttaatccct gatagcggcg tgtcatacag cggaacgacc ggaacgccgc tcatctcctc
    15301 cacgcgcgag tggagaatat taaaggtgaa cacatcggga ataaggatca ccgagcaggt
    15361 ggtgtcggcc agctcgcgca ccagtttttt caccatggcg ccgtcgctca ttgacatggc
    15421 gatataaaca ttgtgaattc gcgaggcttt cgcatcgtca attaactgtt cgaagttccc
    15481 ggcccagtca gcagagacgc cgcccggttt aggatcgtga tagacgccca ccacctcaaa
    15541 acccagccac ggctcattac ggaagctatc cagcaacgcc tggcccgcag gcaaatcccc
    15601 ggcgacggcg ccccggcgag tgttataacc acgattgcgt agccagcccg cgccgaaacg
    15661 aataaatgaa cggcataaca ctaagcccag gctggacagc gcataccagg ccaaccaggt
    15721 ggcgaggcgg ttgtcaaagt catcattaaa cgccaccaga ccggcgctga agatcaggct
    15781 cagcgtccag ttttgcagta acagcgttaa ctctgtcgac attttgacgc cgcgccagga
    15841 gcgataaaaa tcggtcatcc cgcccagcat ttgaaaaaca accagcgtaa tcagcgccac
    15901 caacaggtgc atgtacagga atggcagtcc actgacttca cagatgaacc acagcccgcc
    15961 aaacatgatg gtgatatctg aaaagcgttg caccatagag attaacgatg cattggtttt
    16021 ggctcgttcg cgctttttta gatttgtcat cgttgttcct gtgattggcc ccttacccgc
    16081 aggcggtaag gggagatctg acgttactga ttcagcagcg ccagcagagt gcgtgttcgc
    16141 gcttccatca gcggaatatc gccgcgtgat tccacattca ggcgcaccac cggttcggtg
    16201 ttcgacgagc gcaggttgaa acgccagtcg gcgaacgaca tgctgaggcc gtccgtgcgg
    16261 tccactgcct gcgcctcttc cgcgaagtgc gcttccaccc gcgcgatggc cgccgccggc
    16321 tccgccagtc tgctgttgat ttccccgctc gccgggaacg ccgccatccg gtcgcgaacc
    16381 agttcaccca gcgactgccc cttcaggcat accagttccg ccaccagcag ccacgggatc
    16441 atcccgctgt cgcagtaggc aaaatcacgg aaatagtgat gcgcgctcat ttccccgcca
    16501 taaatggcat cctccgtacg catccgctcc ttgataaagg cgtgcccggt ttttgacatc
    16561 accggcgtcc cgcccgccgc cgtcaccact gcctcggtgt tccaggtcag gcgcgggtcg
    16621 tggataatct tcgcccccgg gtgtttttcc agaaacgctt ccgccagcag cccgacgatg
    16681 tagtacccct cgataaactt ccctttctca tcgaacagga agcagcggtc gaagtcgccg
    16741 tcaaaggcga tgcccatgtc cgccccgtgt tcaataacgg ccttgcgggt gtcgtcgcga
    16801 cactccggca gcaacgggtt gggaatgcct ttcgggaagg tgccgtccgg ggtgttgtgg
    16861 attttgatga actccaccgg cgcgcccagc gccttcaggc gcgcttcaat ggcgtcaatg
    16921 accggccccg ccgcgccgtt gccggcgtta aacaccagct tcagcggggt gagattgtta
    16981 acactgatgt agccgagcag gtggtcgatg taggcgtcgc gcatgctgat ttgtctgtag
    17041 ctgccgcgcg tggcgtcgtt gaccggcggg aagtcgcccg cttccgccag gcgctgaacg
    17101 tcgcgcagac cggtgtcgcc gcttatcggg cgggcgccct cgcgcaccag cttcataccg
    17161 ttgtagtcca tcgggttatg gctggcggtc acttcaatac cgccgtccac gccgaggtgg
    17221 aaggtggcga agtaaatctc ttcggtgccg gacataccga tatccagcac gtcgacgccc
    17281 gcgtcctgta acccttttgc cagcgccatc ttcagcacct cgctggtcag gcgcacgtcg
    17341 ccgcccagca cgatggtttt cggttttaaa tattcgccat aggcgcggcc aatccgccac
    17401 gcgatatctt cattgagctc ttcgcccagc ctgccgcgaa tgtcgtaggc cttgaaacag
    17461 gttaattttg tcatgtgctt acccttcttc aggcaacagt tagccctgac cgcaaatggc
    17521 caacatcgtt attgttattc attgccggat ggcgcgttgc gcttaccggg cataattgca
    17581 ggcgtcagac ccgcccgtaa cggtcctcga accgcaccac gtcgtcctct tcgagatacg
    17641 agccggaacg cacttcaatt aaatcgagcg gtatttttcc cggattttcc aggcagtggg
    17701 tcgcccccag cggaatatag atggactcgt tttcaccgag cagcttaacc tcgccgttga
    17761 tggtgactct ggcggtcccc gccaccacca cccagtgctc ggcacggtga tggtgcatct
    17821 gcaccgacag tccttccccc ggcttaacgg taatgcgctt cacctgatag cgctcgcccg
    17881 cgtcgatgga gtcgtatttg ccccacggac ggtaaacctc gcggtgcatg tggtgctcat
    17941 ggcgtccgtc ggccttgatc ttctccacca cctttttcac gtcctgcacc gcgtggcgat
    18001 cggcaatcag cacggcgtct ttggtctgca ccaccaccag atccttcacg ccgacggtgg
    18061 tcaccaggcc ggattcggcg taaacgtagc tgttttccgt tttatgactg atgacgtcgc
    18121 cgtggtggac gtttccctcc ggggtgtggg cgctgatttc ccacagtgag gaccacgagc
    18181 cgacatcgct ccagcccgcg tccattggca tcaccaccgc gtccgccgtc cgctccatca
    18241 ccgcgtagtc aatggactct tccggacagg cgaggaaggc ctcttcatcc acgcgaatga
    18301 agtcaagatc cggatcgacg ccgcgcatcg cctgttcaca ggcggccaga atatcggggc
    18361 ggaacttttt cagctcttcc agatagcgtc cggcgcggaa tagaaacatg ccgctgttcc
    18421 agtagtaatc gccgctggcg acgtaggcct gggcggtttc cagccccggc ttctcaacga
    18481 actgcgccac ctcaaaagcc accgcatccg tcgcgcccgg cacgacatca ccgcgccgga
    18541 tatagccata gccggtttcc ggcagatccg gcacgatacc gaaggtcacc agtttgcccg
    18601 cgtcggcata gggcatggcg ccgcgcaccg cgtcgcggaa ggcctcttca ttggcgatcg
    18661 catgatccgc cgccagtacc agcatcagcg gatcgcagtc cgtatgctgg cgcgtcgctg
    18721 ccagcgccgc caacgcaatc gccggcgcgg tattgcgccc ggcgggctca agaataatgt
    18781 tctccgtcag cttattgagc tggcggagct gttcggcgac gataaaacgg tgctgttcgt
    18841 tgcagataac caccgggctt tcgcactcca cgccgttcag acggcaaatg gtggtttgca
    18901 acatggtgag atcgcctttc aggcacaaaa actgttttgg ataaagcacg cgagaaagcg
    18961 gccacaatcg gctaccggag ccaccggcca tcacaaccgg gtaaagtttt gtctgacgca
    19021 ttatcatccc cgaatatctg caataaattg gcgtagcacg ttctctttat tgagcgtgcg
    19081 ttcggcgtat tcacgtgccg tcgtgttgtt tttcggcatg gcgagcgcct ggctaatccc
    19141 gtcgaccagc gcgtcggtcg actccggctc cacgcaaacg gcgatgcccg gatagcgcgc
    19201 gcaaagttgt cctaattcgg tgtgcggctc agcggtaatc accgcattac cgccgaccgc
    19261 cagaatgtta gtcagcttgg agggcagtac cgcatccgct gcgccgcgct tttgcaccac
    19321 cagatggcag tcgcccattt tcagcagcgc gggtaaggcg tcgtaaggct gcagcgggag
    19381 gaatttaata tttagcaggc cgcgttcgcg ggccatgttc tccagccgcg ccttgccgcc
    19441 cccctggccg acaatcgcaa aaatcaacgg tcgatcgcgt aatcgttctg cggcgtcaat
    19501 caccttttcc agcccttgtt tttcgccgat attgccggaa tagagcacga tttttttgcc
    19561 ctctggcaag ccaagctgct gacgcaaagc cgtcacgtca gcgtcattaa cgtcctgaaa
    19621 gcgcgccact tccgaccagt ttggaaaaaa gaggattttt tccgccgcga cgcccttttc
    19681 ccgcgcttta ttcatcatgg agcgagagat ggtcgaaaca ttatcaacgt tacgcagcgc
    19741 gctgcgttca aaggccgtcg ctaaccgcgc tacgctgccg cgcttgcctt ttcccgccat
    19801 tcctaagccg agcatggcgt ccacttcgta atcctgaata tgcagtacgg tacgcgcgcc
    19861 ggagagtgtc gccagcagac gcattcccgg cgtacaaaag agcgtcggta caacgccgat
    19921 aatccgatcc ggcttccagc gacgctgcgc catcagtggg aaaaaactgc tcaatgcaaa
    19981 gctccccaga tgaagcagtc gttttagggt ggagggctgt ttcggcacat acagcgggca
    20041 gcgccagacg gtagcctcgc cctcttcccg gcgatagcgc caggcggaat agcgctcacc
    20101 gaccttccac tgcgggtagt acggcggcgc agtaataacc cgcacctcat ggccttcccg
    20161 cgccatccac gccaccattt cgccggtata tttgccgata ccggtcagtt ccggtgaata
    20221 gttaatgcca tagaccagga tcttcatagg cccaccgccg gcgcgtcagg agagaagtag
    20281 gcccgactgt tctcatgaac attgtcgcct gccagaagct gttccggcgt cagccagcgg
    20341 taactgccat gctgggcatc aggcaggcgt aaatcgctct ccgccacgcg cagacgaaag
    20401 ccgagcacga tgtagtgagt tgaaaaatcc tcactggaaa agttgtcgtc atagaagtgc
    20461 tgccagacgc cataaaacgt ccctgccgcc agcggcagac gcacgcccag ttccgcctgc
    20521 gtcaggcgtg caaaagcggc ctccagcgtt tcgtctttgc acacccgccc ccccggcaca
    20581 aaccagtagc cctgcgccgg acggttgagg cgctggccca gcaaaatttc cccctggccg
    20641 ttttccacga tgaaatcgag ggagatgagg ggcgtggtcc gcaccacggc ggcgaaatct
    20701 tcctgacgta aaaacattgt cacccccgga accgttgctg attctcaagg aaccactggt
    20761 aagtaccggc aagccctgcc tccagtgaaa tttcgtgata ccagccaagc tgatgcaggc
    20821 gcgtgacgtc gagcaattta cgcggcgtgc cgtccggctt cgcggcgtcg aacaccaccc
    20881 ggccctggta acccaccacc tttgcgatgg tctgcgccag ctcgcgaatg gtgcagtcca
    20941 cgccagtgcc gacgttaatg tgcgacagca tcggggcggt gttctcctgc cacacttcgc
    21001 gcgccagctc catcacgtga atgctggccg ccgccatatc gtcaacgtgc agaaattcgc
    21061 gcatcggcgt gccgctgccc cacaccacca cctccggcgc gtggctctgc gcagcctcat
    21121 gaaagcgacg cagcagcgcc gggatcacat gtgaattgtc cgggtggaaa ttatcatgcg
    21181 ggccgtacag gttggttggc atcaccgaac ggtagtcgcg accgtactgc cggttgtagg
    21241 actcgcacag tttaatcccg gcgatcttgg cgatggcata cggctcgttg gtcggctcca
    21301 gcgtcccctg cagcagctcg ctttccgcca tcggctgcct tgccagtttc ggatagatac
    21361 aggacgaacc gagaaacagc agtttgttca cgttgtgcag gtgcgcggcg tgaataatgt
    21421 tgctctctat catcatgttt tcataaataa aatccgccgg atacgtgttg ttggcaacaa
    21481 tgccgcccac tttcgccgcc gccagataaa cctggtcgat acccgctccg gcaaagaacg
    21541 cctgtaccgc gcgcccgtcg agcagatcca gctcatcgcg ggtgcgcagc accagttcca
    21601 cgtcgccgcg ctgcgcaagc tgccgtacaa tggcggagcc caccatcccg cgatggcccg
    21661 ccacaaaaat tcgttgctta ttcattctca ggactccagc gcgatggcca cctcgtaacc
    21721 gtgagatttc agcagtgagt gttttttcgc ggcctccaga tcgttcgcca ccatctcgga
    21781 gaccatctcc gacagggtaa tttccggttt ccagcccagt ttctcatgcg ctttggacgg
    21841 atcgcccagc agggtttcca cttccgccgg acggaaataa cacggatcaa cggccacaat
    21901 cacatccctc ggtttcacgc ccggcgcatc gtgtccggta acggatacca cgatcccttt
    21961 ctcattaatg ccttcgcctt caaagcgcag ttttatcccc agttgcgccg ccgccagctc
    22021 cacaaactgg cgtacggaat actgcacgcc ggtggcaatc acgaaatctt ccggctgctc
    22081 ctgctgtaac atcatccact gcatccgtac gtaatctttc gcatggcccc agtcgcgcag
    22141 cgagtccatg ttgccgagat acaggcagga ctccagtccc tgggcgatat tggcgatggc
    22201 gcgggtgatc ttacgggtga cgaaggtttc gccacgacgc ggagactcgt ggttaaacag
    22261 aatgccgtta caggcgtaaa taccgtagga ttcacggtag ttgacggtga tccagtaggc
    22321 gtacagtttc gccaccgcat agggagaacg cgggtagaac ggcgtggtct ctttctgcgg
    22381 gatttcctgc accagcccgt acagttcaga ggtggaggcc tggtagaaac gcgttttctt
    22441 ttcaagaccg aggaagcgga tcgcctccag caggcgcaga gtgcccatcg catccacatc
    22501 ggcggtatat tccggcgact caaacgacac cgccacgtgg ctcatcgcgc ccaggttgta
    22561 gacctcatcc ggctgcactt cttgtaaaat gcgggtcagg tttgaggcgt cggtcaggtc
    22621 gccataatgc agatgaaatt tcgggttgca gctgtgcggg tcctgataaa tatggtccac
    22681 gcgctcggta ttaaacgatg acgcgcgacg cttgatacca tgcacctcat accctttttc
    22741 cagcagaaat tctgccaggt aagacccatc ctgtccggtt acgccagtaa tgagagcgac
    22801 ttttgacatt ttcatttcct caaatagtcc cgttagggag taactttctg aacgcgctgg
    22861 cgcgttacca ctgcgggatt gccccgacaa atcgcatttg ccggtaatga tttaaatacg
    22921 ctgctacgcg cgccgacgac ggtgccatga cctatcgtca cgccgggcgc gacaaaaaca
    22981 tcggtcgcca gccaacattt ttcgccaata acaatcggcg cggcgttaat atcgaaatgg
    23041 gcgctggtat aatcatggct accggtacat aaataacctt tttgtgaaat aaccgcatgt
    23101 gcgccaatat taatttcacc caacgtatat aacacagcgt cgtcgcctat ccaggcataa
    23161 tcgccgacgg ttaatttcca cggataggta atttttactg acggtcgaat aaccacattt
    23221 tttccaattt tggcgccaaa cagacgcagc aaaaaggctc gccagcgata caatatttgc
    23281 ggcgatccgg cgaataatgt cgcctgtacc gcccaccata attgtacttt tagcgcatta
    23341 gcgccgcgga accctttcgg caccgtaaag ccgctaagat cctgcataat aactcccggt
    23401 gattagactt tgttataccg cgcttttgtt ttacccgtcg ttttcagacg taacaaatag
    23461 gataattgcg cccaaaaccc tggaacacgt aatatttttc gctgtacgtt ttttgcatcc
    23521 tgacataatt ccagattatt cgaggttgac acgccgccca tcgaaaattc agataccagt
    23581 ccgttaattc gccgaaaagg atagcctgct ttatagagac gggccgccag cgcataatct
    23641 gaagagacat gatattgcag atcataagga tactttttta acgctgccgt cgggaaaaat
    23701 atcgcctgat ggctggctgg caaactatgg tagatataat acccgggttt agctttccgg
    23761 cgtattttat gcccgccgcc gaaatccagc agcgcgtcgc caatatacat cgcctcgccc
    23821 ttttgccgcg ccagttggcg gacaaacagc gcggcatcat catggaacgc atcaccggaa
    23881 ttaagaaaca gggtatagcg cccctgcgcc aaggcaatgc ctttgttcat ggcatcataa
    23941 ataccgcgat ccttttcact gataaaacgc aggttaaact caccgtgacg tttttgcaga
    24001 aattcgcgcg tgccgtcctc cgaaccgcca tccactacga tccattcaaa tgacaggccc
    24061 ggatcgcgcg ccagattgcg cagcgagcgc caggttttta ccaccccttc gtaattgcga
    24121 aaggcgacgg taacgacgct taaaaacatg caaccacccc gttatgaaat ttttaacgcc
    24181 ttgcgcaaaa tgaacggaca gacgattaaa aaagcatatt ccgggctaaa tattgaaccg
    24241 gtaaaaaaca gcgacaccgg cgtaaaaaga tagagctgca cccgaaaatt gcgattatcg
    24301 ccaaacgcat ttagcgccat ttttaaaact ttccccatat accacagcgt cattagcact
    24361 gcgaaccagg aaaaataaat aatcagcaga tacaatccat tgtctatggt tttcccgaca
    24421 tccgcaccgt taaagattcc gaatgatgcg acatattcat aaagtgagcc aaatctgact
    24481 acaccatcaa tatgggtcaa ggaatatccg accatgacta acgggcccac aatacgataa
    24541 taagaagata atccttccgt ccctaaatcg ccaagtcgtg tcgcgatata aggaaatgca
    24601 ataattaccc caaccaaaaa cagggttaat gataccagcg ccagtggaag ttttttcttt
    24661 atcgcatcct tattcaaata ttggaacgcc cactccagaa ggtaaaacag gataaaggtc
    24721 attacccctg aaaatgatcc tgataatatt atccctgcca gaatcatagc atcgcttttc
    24781 ggtattttga taccaaactg tttgatgctc agccaaattg agattagtgc caaagcgaaa
    24841 aatgccggtt caaaataaag cgcagtggta cgcttaccgc caaattttat gaagttcagt
    24901 acgtagctat tactgtaaat gagatatttc gaaattcctt ccatgatact gctgccgccg
    24961 gtaaggataa tttgcgccat ctcaaccgcg gcgagcgcga ccactatacc caccaccaga
    25021 taaaaaacgc aaaatctttc ggtggttatg cgcggaaatg gttttgaatc ggatactcca
    25081 gaccatcccg ataatgacca caatatagac aaacagcatc gtggacgtga catatttacc
    25141 ggcattcagc gactggccga acaggaagtt aaatgccgta agccccgcgc cgatgcctaa
    25201 ggcgatcatc aattttttta cgctaatgcg ttccacaaat aacagcagca acagcggtaa
    25261 aaaagtgacg atggtaatgg gaaagctttc ccccagttgg gcaatcttga cattgaccag
    25321 taggtagatc agcggcagca gcagatagct acagattctg atagaacgag acatactcct
    25381 ccagcatctg ttgaccgctg tacgcgacgc ggctacgcat acgaaaggcg tccagcgttg
    25441 cgccgaatac cgcctgagca atctctggct tacgccgctg cgccaggcgc agtacatctg
    25501 tagcggcaaa agtctggccg ccggatttcg ccagcacctc ctgcgccgcc tcgctgtggg
    25561 tggcgattac cggtacgccg atcgagagcg cttcacacaa gatcagcgga tagttatcga
    25621 cccgcgagct aaagaccagc gcgtccatct cattgagcgc gctcattaat ttgcgcttat
    25681 cggtttcaaa accgtgatta acgacgtttt ggccggtaaa aggcgaaaat ttaccgaagg
    25741 tatgcagttc aattttttcg cccagcgcca tcatgtcgtg taccagacgc tggtcagttt
    25801 tgccgtcgta acgcaagtca tgcgccacaa tggcgatccg cggtttgccc ggattcagcg
    25861 gcacaggtga tagttgcgcg agaatcgcct cggtcgccag atcgataccg ttgttaatca
    25921 cccggcagag tcccgcgcca taaacgctgt taaaggcctc ggccacatgc tggctcggcg
    25981 aaataaactg gcagcccagc cgcagcatgt cacgaaagcg ctgacgtttg ccgtcaataa
    26041 gctggtgcgc ccgatccacc ctgactggcg gataattgct tagggtcgga catttttggc
    26101 agccgctttt ccagccctcg caaccgtcgg tgaaggcgca acgcccggta acgctccagt
    26161 gatcgtgcag cgtccagacc agcgtgacgt ccggtttttg tgctttgact ttttcgcaaa
    26221 acgtcacgat atccgccagg tttagccagt aactgtggag aacatgaaaa tgcagcacca
    26281 gcgggccgga tgtctggata accgtgcggt aaagattgtc gagattgcca aacagatcgc
    26341 gattcaggaa acgaaatagc gcgatattgg cgattgccgt gccgcgcggc gtctgtttta
    26401 tcacctgcgg ataacggtgg tgactgacgc ttttttttcc gcctttgcca taaccataaa
    26461 caaaatgcga cgtcagccct ttttgcagcg cccgcagatg aagatctaac gccactcccg
    26521 ccgcaccgcc ttccgccagc cgtacattaa attgcagaat attcatgtgc tgaccttcac
    26581 ccgtgctttt tctcccacca ccagcgcatg atccggaata ctgtcaagca ccacgctacc
    26641 cgcgccaatc gtgacgtgat taccgatagt aatatcgcca agcaggatga cgttcgcccc
    26701 cagctcaacg ccgtgaccaa tcaccggaca agccaggctg tccgcgccgc gattgccaat
    26761 ggtgacgccg tggcgaatgg taaaatcgtc gccggcgacg acatgtttgt tgatcactac
    26821 cgcgtaacca tgatggatag tgaaccgccg accaatggtc gcggcggcct ggatttcata
    26881 cccgaacagg cattccgtga tcacgcgata cagcaccagc accggcgcgg cccacagatt
    26941 attcagcaca ttctttttgc gccagacgga acaaaaatga gcgatacggt aggccagcac
    27001 catgcaacag gggcgtaagc tccagctatt cgcgcgtaag tcttccagca tcgttatcgc
    27061 ccccgcagcc cggccgccag gcgtttgcta ttacgcacgg agagcaacgt cagcaacgtg
    27121 cgccaggtca ttcgcttatt gcgaatttgg tacagcgtaa aaagctggta ttttttgctg
    27181 gcgcgatcga atttatcttt gtgcttacga taaaaatgga aatagccgga gaactttttc
    27241 ggcgaagagg taatctgcat ctcgccgtgg ttgatatgta aaatttgcgt cgcctcttca
    27301 actttccacg gttcgccata ctccaccacc atgcgcagaa aaatgtcgta atcctgcgcc
    27361 gccttgagtt cggtatcgaa caaacacgct ttaaaacgcc aggcccaggt aaaaacctga
    27421 ttgccaataa tattgcgctt gtagaacaag cggcgcgaat aaggggattt cggatacagc
    27481 ggcaggctgg caggctgaga gtagacctcg ccctcgcaca catagtcgtt ggcatacaaa
    27541 aaggcatgcg tagtcaactg gtgtttatgg gccagaaaca cgctcagacg gttgggcgtc
    27601 cattcatcgt catcatcaat cccggtaatg tagtgtcctt gcgcctgcat aatggcctgg
    27661 ttgcgaaccg cgcaggcgcc ggtattcatg gcgttatgag tataacgaac gcgcgggtcg
    27721 ttcagctcct caacaaattg ttgtagctgc tgataagacg aggagcaatc atccacgatg
    27781 atcatctccc agtgacggta gtcctgacgt agtactgatt taatcgcccg gatagccaac
    27841 tgctgcctgt tccaggttgg catataaatt gagatcagcg gattgtctgt tgtcatgctt
    27901 attccccaga tagttttgcc gcatggcgct acgcttgtcc ggcctacagt cacaggccgc
    27961 gccatccggc acgccttatt ttttatttgg aatctgactg gtattcatac tcgtaatagc
    28021 cataatcctg gtagcccgtc gcccggcgga aaatggagtt gagaatgacg cctttgacct
    28081 gaatgccatt ctggtcaaaa cggctcagac tggtttccac ttctttcaag gtgttgacgg
    28141 cataacgcgc caccatcagc gtcgtcccga cgtgacgacc cacaatcgcg gcgtccgtca
    28201 cggccagaat cggcggcgtg tcgattaata ccaggtcgta gcggctgctt gcccaggcga
    28261 tcagctcgcc gaagcgctcg ctcatcagca attccgatgg attaggcggt acctgaccgc
    28321 gcggaataag atcaaaatta gcgatcgccg tgggtttcgc gcaggaggct atctcgcctt
    28381 tgcccgccag aatgtcagat aagccgtcca cgttattggt gccgagcagt tcatgggtgt
    28441 agcccttgcg catatcgcag tcgatcagta atacccgttt atgcgtctgg ctgatgacgg
    28501 ccgccaggtt ggcgcaaaca aaggttttac cgatagagga gctgacgcct gtgagcatga
    28561 gtacattatt ttgcgcctgc atcatggcga aatggaggct ggtgcgcagg ctgcgaatcg
    28621 cctcaatcgc cagatcggtc ggattgccca ccgccagcag ttggctctgc ttgtaacgct
    28681 taatcccttt aatggttttg acgctatcgc gcgctttttg ccattccgac agcggaatac
    28741 tggcatagac gctgatcccg tgctcctcca gcgcctgcgg gctttcgata ccgcgattaa
    28801 acagcgagcg cagcagcacg ccgacaatcg ataacattaa tcccagaata atgctgccga
    28861 gaataatcaa cgcctttttc ggctttagca cgcccggctg ggtaatcgcc gggtcaacga
    28921 tgcgcacgtt gccaacggtg ctggcttcgg tgattttcag ctcctgctgt ttattaagca
    28981 gttgcatata aacctgctgg ccggactcca catcgcgggt caaacgcaca atctcctgct
    29041 gggttttcgg catcgccgtc acccgcccgt tcagtttggc ttttttatct tccagccctt
    29101 tacgtttttc cagcagggtg cggtaagccg gatgcgcttt ggtaaagagc ttggaaattt
    29161 ccgcttcttt aaacgtcaac tcattcaact gggcgtcgat attaaccatc gaatcgagca
    29221 ccgccttcgc ctccagcggt aaatccaccg agtctttatc ctggcggaaa gcgtttagct
    29281 tgttttccgc cacatccaga cggctgcgga cttccggcag ttgttttgcc agaaacgcca
    29341 ggctcttccc cgcctcttca gatttccacg caatatcctg ttgcagatag ttacgggtaa
    29401 tactgttgag aatgtcgcgg atctggtcgc gatcctctcc cgtgaacgtc aggttcagaa
    29461 cgccggtatc tttgccggtt tccgttacgg tgaggttatt ttgcaggtta ttaatcatgc
    29521 caagcgttga gaatttactc accgtaaatt ccgtatcagg acgggcgtca atcgcctcta
    29581 cccgcatcgt cacgccgtct ttattgagtg gctggcccac aacgccctgc gcgctaaatc
    29641 cgccgtcgct gaccaactga taacgtttgt cgcccagcac tttgagggtg aagatctgtc
    29701 cgctcatcgt ctctggtcgg gtgaatgtcg tgactttcac catttcattg tgacgtccca
    29761 tcagccgctc ccacccggcg ccgaacagcg gaaaggtgtt tttggtgacg gcaatatcca
    29821 gatccagatc gtcaacggtc ttccccagca ccaggcgcga tcgaatgagc tgaatttccg
    29881 catcggaagc cggcggctta ttcgctaatg cgctgttgat atcctgtacc agcgaattac
    29941 cggcgttttg ttcaatctgc accagcgcat cggcgctata gatgggcgtg gcgaagaacg
    30001 tataaattac cgcgcacagc gcaaatatgg ccgtcgtccc caacacccac caacgcgctt
    30061 caatcaccgt tccgaccaga cgcccgatat cgatttcatc gctacccgta accgccgcag
    30121 attgttttac tttttctgtc atggttttcc ctgctctgca ttcagtgcct gcgcccactg
    30181 gcgggcagac ctttccagta atgtgtacac cgcctcaaac gcatcgcggc ttttgcgata
    30241 cgggtctggt atttcacgct cgctgtccca gtgaccaaac agcattacct tgctgcgcat
    30301 ttccggcgca atgtcgcaca gggcggcgat gtggcgtttc tccatcgtca gaatcaggtc
    30361 atattcccgg cacaggcgcg cggaaatttg ccttgcgcag tgattttcca aagacagatc
    30421 gtgggcgctc gccacgctcg ccgccgcagg atcggctcct ttgccgacca gcgcgcctaa
    30481 tccggcagac gcaaccgtca gcgaaggatg aaagcgcttt agcaaacgtt ccgccgtcgg
    30541 ggaacggcaa acattcccca cacagaccac taagattttg ttaaacataa cgattaccag
    30601 gaatgaatgt cgctggccgt atccgtcata taacggacac cgctaatggt cggcagcaac
    30661 tgattgatca gacggttcca gcgagcaacc ggcgcggtcg tgacgtacac cacatcgtaa
    30721 ggctgaagtc ggaattccgt cgccatcacc aatgacgtgg cgtcagacat atcaagctgg
    30781 tagatattgg cgatcttgcc gccgcgtccc ccctcgcctt tcaacggacg aatcacaaaa
    30841 atgccgctgg cgttggaggt ggtcagatcg atgccttccg cattgcctaa tgcttcggtg
    30901 agcgtcatgc tgctgaaatc cattttgagg gtgctctgtt ttttcacttc gcccatgaca
    30961 aagactttca gatcgtcatt gcgcggcaca tacagaatgt cgccagggta gagcaagcgg
    31021 ttctgactaa gatcgccatt ttgcatcagc gcctgtagcg aaatgcgctg ttctttgccg
    31081 ttgtgcgtca acacgacgtt gcgccagtcc gccatatcgg tcaggccgcc cgcagcgtta
    31141 atcgcatcca ggacggttag cgggacgtta gtaatggcct gctgaccgga tttattcacc
    31201 tggccggaga tatacgcttt ttgcgagcgg aaagcggcga tattgacatc cacctgcggg
    31261 tctgcgatgt acttcgctaa acgcccggta atatcgctgc gaatctctga caaagtttta
    31321 ccgacgacgc taaccttgcc aatataggga taaaacatgg tgccgtccgg ctgagcccag
    31381 ttgccggtat cgcttgagct acggtactgg cctgctggcg tggtcaattc cgggtgatcc
    31441 cagacggtga cattcagcac atcgccaggc ccgacgcgat actgatagct ggcgatctcc
    31501 tggtccagcg acatattcgg ttgcgcgaca ttgggccgcg ggcgtaattg ctcaaccagc
    31561 cgtggcgtca gcggatacac attgaccatc cggtcgagat caaagtcagc gtcttgctgt
    31621 ttgatcacat ctttccccat cgtagacata ttgctgcccg ggagtactgt gcaaccactt
    31681 atcaagctga gcgacgccaa taatggcatc aatttcattt tggatttcat cattgattat
    31741 ttatcacttt ggcagagtca ttatcctgtg caatttaaat agcggcttcg tccgtgcaca
    31801 tttaccttgc agttaatggc agagaaaatt aactggcatc attctgaaaa aaatcaattc
    31861 atccgcaggc tattgacaga ataataaagt cttatattca ggctttcagg cacgctaccg
    31921 cccctagctt cttagctacc aatacactga ttattctaaa ttttcgcatt cccctccaat
    31981 ttcatcctcg ttcagataaa aatcttcagc gaaataaagg ttacgtatta atagttttct
    32041 cgatgtcgtg acaggatatt taagcgcgct atcttaatcc tgcaagaatt gttgcagcta
    32101 acctaatgac aagcaaggta acaaacccgc cattctatat ttttaagatt aatattaaat
    32161 gaattaacag atgattttag gattttattg atgttgacaa tatttattta ctccactcca
    32221 cctgcgatat ttcctaaata tattcttgac attatttagt ttccgacaga aacattacgg
    32281 ctattttaaa gttattttat agccccgtaa caaagataaa ttgctctgcg gcattgcatt
    32341 tttccgccgt attatccatg atcgaattgt gacaattgtc atattacaga aggtattgct
    32401 cttactatgg aatggattgc cgatccgtca atctgggccg gactggtaac gttaatcgtt
    32461 atcgaacttg ttctcggcat tgataacctg gtctttattg ccatcctcgc tgaaaaacta
    32521 ccgccggggc agcgcgaccg cgcgcgcatt accggcctga tactggcgat gatcatgcgc
    32581 ctgctgctgc tggcgtcaat ctcgtggctg gtcaccttga ctaagccgct ctttagcgta
    32641 caggcgttaa gctttagcgc ccgcgatctg attatgctgt tcggcggctt cttcctgctc
    32701 tttaaagcca ccatggagct caacgaacgg ctggaaggga aagatagcgc caaccctacc
    32761 cagcgtaagg gggcgaaatt ctgggcggtg gtcgcgcaaa tagtggtgct ggacgctatc
    32821 ttttctctcg actccgtgat taccgccgtg gggatggtcg atcacctagc ggtcatgatg
    32881 gcggccgtga taatcgccat tagcctgatg ctgctcgcca gcaagtccct gacccgattt
    32941 gtgaacaacc atcccaccat tgtcattttg tgccttagct tcctgctaat gatcggcttt
    33001 agcctggtgg cggaagggtt tggtttccac attccgaaag ggtatctgta cgcggctatc
    33061 ggcttctcgg tgatgatcga ggcgctcaac caactggcta tttttaaccg ccgccgtttt
    33121 ctttccgcta accatacgct gcgccagcgc acaacggagg ccgtgatgcg gctgattagc
    33181 ggtaaaaaag aggatgccga actggatgcg gaaaccgccg cgatgctggc agaccatgac
    33241 gacagccaga tttttaatcc gcaggagcgc aggatgattg agcgggtgct gaatctcaac
    33301 cagcgcaccg taagtagcat catgacgtcg cgtcacgata tcgagcatat cgatctcaac
    33361 gcgccggaag cggaaatccg cgctctgctg gaaaagaacc agcatacgcg tctggtcgtg
    33421 acgggtgaaa atgaacagga agatttactc ggcgtcgtcc acgtcatcga tctgttgcaa
    33481 caatcgctgc gcggcgaacc gctcaacctg cgggcgctga ttcgccaacc gctggttttc
    33541 ccggaaacat tgccgctgct gcctgcgctg gagcagttcc gtaacgccag aacccatttt
    33601 gcctttgtcg tagatgagtt tggctcggtt gaaggcattg tgacattaag cgatgtcatg
    33661 gagactatcg ccggtaatct gccgaatgaa gtcgaggaaa ttgacgcccg ccacgatatt
    33721 cagaagaacc cggacagttc ctggacagca aacggccata tgccgctgga ggatttggtg
    33781 cagtacgtgc cgctaccgct ggatgaaaaa cgggaatacc atacgattgc cggattattg
    33841 atggaatatt tgcaacgcat accgcaaacc ggtgaagagg ttcaggtggg cgattatttg
    33901 ctgaaaacat tgcaggtaga aagccatcga gtgcagaaag tgcagttaat tccgctgcat
    33961 aacggcgagc cagaccagga gatgtaacgt ctgttcgcct gccccggcct gcttaccagg
    34021 caggccggag gcgcgttagc ctcgccatcc ggctctgccc tttggccaaa aactacagct
    34081 tattcagcag cttcttcaca tctttaccgt tgcgggtatc tttattgcga tccgcccagt
    34141 cattgagccg acgcttcgcc tcatcctgta aatgcttacg caataactgc tccacttgca
    34201 gggtatagtt cagctcctgc cacttgccat agacgcgcaa cggcaccggc gtctctttca
    34261 ggaaggtgat caggttgcta tcgccgttcc agccgcccag cacacgcaga ttaaattgtg
    34321 tatcacagct ctgcttaacc agatccagcg ttccgctgcc ggttaacgcc agcatagaag
    34381 attgcccgac catgtcgtcg agcgtcagcg tgcccttatt tagcgtcaga tcggtcgtga
    34441 agcgatccag tcgggtcgcg ttgtccatat tttcctgcga ctgctgcgcg tcgccgccgc
    34501 ttcgctctac ggcctgctgc accagttgct ggaaattcat tccttcaagg cgcgtattgc
    34561 tcatgtcaac atgcgctttt cctttccaac tatggcgaaa tgcctctgcg tcaatatccg
    34621 ccccggagaa atcgccaacc agcgacatct taccggtcag gctaatcgga taattgaagg
    34681 ctttcaggat agtcccaatc tcaacatggt tgaggcgagg gtggaattcg atgcgcggac
    34741 tggcggtgcg ggcgtccagc gtgccgggca gcgacatctc tccgtcggcc agtttcccct
    34801 gcaactcagt aatatccagc aatccggtct gattagacat cttcgtcgaa acctgggtaa
    34861 agtccattcc ccgccagcga actgaatccg cctgtaaagc aatctccgcc gtaaagcttt
    34921 gcagcccctg ataaggcggc gcaccaacac gcgacgcgat aactggcctg gtcaggggga
    34981 gcgtattttg cccctgcgac accgcgccgc ctgtctgagc cacggcgcta tgatgcggca
    35041 acaggttgtc cagattaagc ttgctggacc ggaggtcaat ttgccattcc ggctgctccg
    35101 ccagcgttac ctgaacatgc ccggtcagag aactgtcatt cgccgttaaa tttaagtggt
    35161 taaatgaaag acgtttttgc gcctcctgcc actgcgcctg caattgtccc tgcccctcaa
    35221 tcccctgcgc cggtagatcc gcgccctgca attgccagcg cagttgctca atacccgcgg
    35281 ttaaattatg cggataatcg gaagcatcca ccgttccgct gaacgataaa gcaagatccc
    35341 gctgatcgcg gttcacgcgt cccgaaaaat caaacgtgcc gcgatgctcg gcatcttgtt
    35401 ccatattcag acgaatatcg cgcaccgtga cctgatcatc attttcatgc tggaaaacca
    35461 gcacgctgcc ggcaacgcgc aggctacgaa tatcaaacga ccagccgcga tcttccgcta
    35521 cgtccggcaa ggtattatct ttcggcgcga ccggcgcatc atcactgcgt accgcttccg
    35581 tttgcggcgt cagttgaatc accccgcctt tcagcatcac ctgcttaaca tgaagctgat
    35641 gactcaacag cggccataaa gcgacatcca ggcgcatatt gtcagcccgc accagcggtt
    35701 cgctggcgcc tcgcgccgtt agcgtcattc gcccggaaag gatactgagt tgcggccata
    35761 cgtgccagcg cagcggcccg tccagttgca actgatattc actacgcgcg gcaacctgct
    35821 gcaccatata ggcgcggaaa tcattcggat tgaccaacaa taccaacgca gagaatccgg
    35881 ccaccagcac gaccaagaga atcatcagcg tcgtcagaaa tcgtctcatg ctaccctcaa
    35941 tggaccggca gtattgcgcc gaatggctca gtctttatca atccggctgg caacagcgcc
    36001 ctgctgatcg cgatatttgg catcctgacg gcggttataa ggccgcgccg ccgggccgga
    36061 cagcggctca aagctcagcg cgccgatgag catacccgga cgcaacgcca gcggcagctt
    36121 cccggagttg taaaactcaa gcacaatgca gcccgaccag ccgggatcga tacggtgcgc
    36181 cgtcacatgc accatcagtc ccagacgcgc cagcgaggaa cgaccatcca gccagcccac
    36241 taaatccggt ggcagggtaa cggattcaaa ggtgacggcc agcgccaatt cgcctggatg
    36301 cagataaaat gcctcgccgt ccggcaaaac gatttcatcg ctcatcacgc gatccaacgc
    36361 cgcgctgacc tcatctttcg gcccgctcag atcgataaac gccgccgtat ggccacggaa
    36421 ggttcgaaat ttattgccaa gacgtacatc gaccgtcgcg ccgttaatgc gctctacggg
    36481 aggtcgcggg gtgatagaca aacggccttc atccagccag gcttcaatat ctcggtcgca
    36541 taaacgcatg gcactttctc ctttcgcgca tcaagccctt aaatcaagca catcaagggc
    36601 taaccaggtt atcactgaac ggtacacaat tcgccagatt tattcaaaga actggctgat
    36661 tttcgctttc agaatatcaa tagcgatgcg gtttttaccg ccgcgcggca cgataatatc
    36721 cgcatattgt ttggaaggct caataaattg caggaacatc ggacgcaccg ttttctgata
    36781 ttgcgccatc accgaatcca ttgagcgacc acgctcgttc acatcgcgtt tgatacggcg
    36841 catcaaacag atatccagcg gcgtatcgac aaaaatagag aagttcatct cttcacgcaa
    36901 acgcgcgtcg gtcagtaaca gaataccttc aagaataatc actttcttcg gttctacgcg
    36961 aaccgtttcc tgcatacggg tatgctcaac ataactgtat accggtaatt caatcgccga
    37021 accgcgcttg agcgcctgaa gatgctgaaa tagcaggctg tgatccatcg cattcggatg
    37081 gtcatagtta gtttttacgc gttcttccat cgacagatgg ctttgatctt tgtaataact
    37141 gtcttcggga ataacgccaa tatgttcgtc acccacttgt tcacgcaatt cgcggtaaag
    37201 ggtactggca ataagactct tgccggaagc cgatgcgcca gcgataccga taatgacgca
    37261 ctgatgagac tgatcagtca taaatttagc gacctgatta acctggatgt aaagaagggg
    37321 ggcgccgaaa cgccaaacgc ggcaattata gggatttcag cagcgcgata ccagtccggc
    37381 gctatgccac ggtgaatttg ttggcggcgc attcgacgtc gcgacgtaaa agcgttcagt
    37441 tttaatgcgg acagcggatt tatcgacccg tctggaggag gaatacgccg ggagccacaa
    37501 tttatattca gtcagcgtat aaatcattac gcgtttatac tagcataatc acagagtaaa
    37561 ctgacgcgtc cggtattccg cgacgttacc ggcgattcgg atagagtggt aatgagtaaa
    37621 ccatcccaac atgttttcgt taccgtcccc cacccgctat tgcgtctggt cagtttaggc
    37681 ctggtcgcgt ttgtctttac gctcttttcg ctcgtattat cgcgtgtcgg cacccaactc
    37741 gcgccgctgt ggttccccac ctccattatg atggtcgcgt tttaccgcca tgcgggccgt
    37801 ctgtggcctg ggatcgcggt cgcctgctcg ctcggcagca tcggcgcctc actgacttta
    37861 tttcctgccg cctcgcttaa ctttagctgg acggcaataa atattatcga ggcggccact
    37921 ggcgcgatac tgctacgaaa actgctcccc agctacaacc ccttacaaaa tttgaatgac
    37981 tggtttcgtc tggctatcgg cagcgccgtg attccgccgc tactcggcgg cctgttattt
    38041 tggctgatag cgccggaagc ggtcgcctcg aaagcgtttc tgatttgggt attatcggaa
    38101 gccatcggcg cgctgacgct ggtgccgtta ggtttactgt ttaaaccaca ctatctgttg
    38161 cgtcatcgcg acccgcatct gttgctggaa acgctattga cgctggtcat tacgctggcg
    38221 ctaagctggc tcgctatgcg ctatattccg tggccgttta cgtgcgttat cgtcctgttg
    38281 atgtggagtg cggtgcgcct gccgcgaatg gaggcgtttt taattttttt agctaccgtt
    38341 atcgtggtct cgctcatgct ggccaatgac cccacgctgc tcgccacgcc gaaaaccgac
    38401 gtgatggtca atatgccgtg gctgcctttt ttaatgatcc tgctgcctgc caatatgatg
    38461 acgatggtga tgtacgcgtt tcgcacggag cgcaaacata tcaccgagag cgaatcccgc
    38521 tttcgcaacg cgatggagta ttccgccatt ggtatggcgc tggtcggtac ggagggtcag
    38581 tggctacagg tcaataaatc tctgagccat tttcttggct atagccagga tgaattacgc
    38641 acgatgacat ttcagcaatt gacctggccg gaagacctga ataacgacct tgaacagcta
    38701 aacatgctgg tgcgcggcga catcaacagc tattccatgg aaaaacgcta ctacacccgc
    38761 aacggcgatg tcgtctgggc gctgctggcc gtctcgctgg ttcgtcataa agacaatcaa
    38821 cctctctatt ttattgctca gattgaagat attaacgatc tcaagcaaag cgagcaggaa
    38881 aaccagcggt tgatggagcg tattacacag gcgaacgagg cgctgtttca ggaaaaagaa
    38941 cggttgcaca tcacgcttga ctctatcgga gaagcggtgg tgtgtattga tgtcgcgatg
    39001 aatatcacct ttatgaatcc gatcgccgag aagatgagcg gctggcggca agaggatgct
    39061 ttaggcgcgc cattattaac ggttctgcgc attacgtcag gtaataaggg gccgctgctg
    39121 gaggatattt atcgcgccaa caggtcgcga tcggacatgg aacaggagat agtgctccat
    39181 tgtcataacg gcggtagcta cgatattcat tacagtatca cgccgctcag tacgcttgac
    39241 ggcgataaga ttggttcggt tctggttatc caggacgtta ccgaatcacg aaaaatgtta
    39301 cgccagctca gctacagcgc aacgcatgac gccctcaccc aacttgccaa ccgcgccagt
    39361 tttgaaaaac agctgcaaca gcgcctgcaa acaatacagg aatcgcctca acatcatgcg
    39421 ctggtgttta tcgatctgga ccgttttaaa gcggttaacg acagcgcggg acatgccgcc
    39481 ggcgatgcct tattgcgcga gctcgcgtca ctgatgctca gtatgcttcg ctccggcgat
    39541 ctcctggccc gcctgggtgg cgatgagttt ggcctgttgc taccggattg taatagtgac
    39601 agcgcgcgct ttatcgcgac gcggcttatc aacgccgtta atgaatatca ctttatgtgg
    39661 gaaggacgcc tgcatcggat cggcgccagc gccgggatca caatgataaa tgaacataac
    39721 tgccagctca cagaggtcgt gtctcaggcc gatattgcct gctacgccgc gaaaaatagc
    39781 ggtcgaggcc gtctgaccgt gtacgaaccg cagcacgcat taacctcctc aaagggaatg
    39841 atgccgctgg aagaacagtg gcatatgatt aaaaataacc tcctgctaat gcttgccaga
    39901 aacgtcgcgc cgccgcgtac gccggaggcc accagctttt ggctggtctc actcaggctg
    39961 tggaccagcg aaggggaagt gatggaagag cgcgcgttcc gggcagggtt agccgactcc
    40021 gcgctgcatc acgcgcttga ccgacgggta ttccatgagt ttttccgcca tgcggcgacc
    40081 gccgtcgcca gcaagggatt aagcgttgcg ctgccgctgt ccgccgcggg attatacagc
    40141 gcgaccctta ttgatgagct gctggaacaa ctggagcata gcccactgcc gccacggtta
    40201 ttacacctga ttatcccggc tgacgttatc gttaagcagg cgcagaccgc cgctgcgact
    40261 ctgcgaaaac tgcggcaacg cggctgccag gtgattctca gccatgtcgg gcgcgattta
    40321 cagctgttta atttactgcc cccgcatatc gtcgattatt tactgctgga tagcgacctt
    40381 atcgccaacg ttcatgaaag tttaatggat gaaatgctga cctcgatcat ccagggacac
    40441 gcccagcatc tggacatcaa aacgctcgcc gggccggtac aaaacccaca ggtgctggat
    40501 acgctctccc gtattggcgt ggatctgatt tatggcgaca ctatcgccga agcgcaaccg
    40561 ctggatttgt tactgaatac cagctatttc gctatccatt gacggttgcc agccgtgggt
    40621 ataccagata tgcagtagcg cgtaggaacg ccacggtttc cagcgctccg cgtagcgacg
    40681 gatctgcgcg gccgtcatcc cggcgaagcg ctgcttaatt aagtaatcat cgggcaaaaa
    40741 gatatctttt gcctgccaac cgcgcagggc gaaatagttc gccgtccagc ggccaattcc
    40801 cggaaatgtt tgtaaatttt taacgctctg ctcaatatcc ggcggcgcgg agagcgccag
    40861 ttttcccgcc agcgtcgcct gcgccagatg aatcagcgct tcggcgcgcc gcagcggcat
    40921 ccccagagct ttaagcgcca gcggatcggc caacgccagc gtttccggac cgggaaaaca
    40981 gacataatcg ggcgcatccg gcaacgcctc gccatagcgg cgcgccactt tcgccgtcaa
    41041 ccttgccgcc atcgcgacac tcaccagttg ccccagtatc gcccgcacgc cctgttcaaa
    41101 cgtatcaacc gatcccggta aacgcagccc cggtctgtcc tcgcccagtg gccccagcac
    41161 ggcggcaacc tgctcgggct ggcagtcaag atcaaacaga cgcgaaactt tcgccagaca
    41221 cgccggcgcg acgggaagta atccggcgct cacgctaacc tgcacagtgt gggtgggcag
    41281 atggggcctc acgctgacca gtccgcgatg ctcgcccacc accaggctgc gcgcataaaa
    41341 gccctcgcct actgtttcca cgccgtccac cgcacgcgcg gcaagaaagc ccaacatcca
    41401 cgaccagtcg taaggcggct gccagctcag ggtaaacata cttttctcct ttatttgacc
    41461 tttcagcata aacgctaatc gcacgtaacg ccttgctttc atattccagt tgtcgccgcg
    41521 acgacatttc gctaaagtca cgccccttct tcactggcat ggggatttta aggtgtttat
    41581 aggatttgat tacggtacgg caaactgctc ggtcgccatt atgcgcgacg ggcatccaca
    41641 gttgctgaca atggagaata acagcgcatt actgccgtct atgctgtgtg cgccgacgcg
    41701 cgaagcggtg agcgagtggc tgtatcgcca tcatgatgtg ccggcaacgg acgaagaaac
    41761 ccaggcgctg ctacgccgcg ctatacgcta caaccgcgag gaagatattg aggttggcgc
    41821 gcaaagcgta cagtttggtc tggcgtcgct ggcgcactat attgacgatc cccaggaagt
    41881 ctggttcgtc aaatcgccga aatccttttt aggcgccagc ggcctgaaac cgcagcaggt
    41941 cgcgctgttt gaagatttgg tctgcgccat gatggtacat attcttcata cggcgcacag
    42001 ccaattgccg gaggccatta ctcaggcggt gatcggtcgc ccgatcaact ttcagggact
    42061 cggcggcgat gacgcgaacc gccaggcgca gggtattctg gagcgggcag caaaacgcgc
    42121 cggttttcag gaggtggtat tccagtatga accggtcgca gcgggcctgg actacgaggc
    42181 tacgctgcgg gaagagaagc gtgtgctggt cgtggatatt ggcggcggta ccaccgactg
    42241 ttccatgctg ctgatggggc cgcagtggcg tcagcgcgcc gatcgtgaaa acagcctgtt
    42301 ggggcacagc ggttgccgcg tgggcggaaa cgatctggat atcgcgctgg cctttaaaaa
    42361 tctgatgcct ttgctgggca tgggcggcga aaccgaaaaa ggtatcgccc tgccggtgct
    42421 gccgtggtgg aacgccgtcg cgattaacga cgtcccggcg caaagcgatt tttacagtag
    42481 cgcgaatggt cgtctgttga acgatttggt tcgcaacgcg cgtgaagcag acaaggtcgc
    42541 gttgctgctc aaggtctggc gtcagcggct tagctaccgc ctggtacgct gcgcggaaga
    42601 gagcaaaatc gccctttccg gccaggcgga tgttacggcg aggctgccat ttatcagcga
    42661 cgacctggcg gtcgctatca gccagcaagg actggaagcg gcgctggatc aaccgctggc
    42721 gcgtattctg gaacaggtgc aactggcgct ggacagcgcg caggaaaaac cggatgtcat
    42781 ctatctgacc ggcggcagcg cccgttcgcc attgattaaa aaagcgcttt ccgaacagct
    42841 accgggcata cccgtcgctg gcggcgatga tttcggctcc gtcaccgcag gactggcgcg
    42901 ctgggcggag gtcgttttcc gctaagcgcc tcgcaagccc agcgctgatg gattgacatt
    42961 attcttgatg tggcttaacg tcaggagtga gggtaaggga ggattcctcc tccccctggt
    43021 gtcttagtaa gctggtaggc taatcactaa gagtatcacc attatgatga ctaccttcat
    43081 cataaccctt tccttatttt ggccccttcc tcgggagggg ctttcccgtt tcagcatcct
    43141 gctgaaatcg gtggcttatc ttcattgccg tgccggcact ttaccgcact ccggcgcgtt
    43201 aacgattttc accgatgaga gttgcgtagc gcctcgcaaa gcgggtcgcc attcagaata
    43261 atcccgaccg tgttccataa ttcctccatt tttctccctt ccctgctgac tacaatagag
    43321 gaagcaacat tccgcaaaac gtttcaggat gagaaactta taccgatgaa aggcagtaat
    43381 actttccgct gggcaatagc gattggggtt gtagtggccg ccgccgcatt ctggttctgg
    43441 catagccgta gcgaaagccc gaccgccgcg ccgggcgtcg ccgcgcaagc gcagcatacc
    43501 gccgccgcag gtcgccgcgg tatgcgcgac ggccctctgg cgccggtaca ggccgcgacc
    43561 gcgaccacac aggctgtacc gcgctatctg agcgggctgg gtaccgtgac cgcagcgaat
    43621 accgttacgg tgcgtagccg cgtggatggt caactcatcg ccctgcactt tcaggaaggt
    43681 cagcaggtta acgcaggcga tctgctggcg caaatcgatc ccagccagtt taaggtcgcc
    43741 ctggcgcagg ctcagggaca gttagcgaaa gataacgcta cgttggcgaa tgcgcgtcgt
    43801 gatctggcgc gctatcagca actggccaaa accaatctgg tttcccgtca ggaactggat
    43861 gcgcaacagg cgctggtcaa cgaaacccag ggaaccatta aagcggatga agccaatgtc
    43921 gccagcgcgc agctacagct cgactggagt cgtatcacag ccccggtctc gggacgcgtg
    43981 ggtctgaaac aggtggatgt cggcaaccag atttccagca gcgataccgc aggtattgtc
    44041 gtcattacgc aaacgcaccc gattgatctc atttttactc tgccggaaag cgatatcgcg
    44101 accgtggttc aggcacagaa agcggggaaa acgctggtcg tagaagcctg ggatcgaact
    44161 aactcgcaca aattgagcga aggcgtgttg ctcagtctgg acaaccagat tgatcccacg
    44221 acgggaacga tcaaaattaa agcgcgcttt accaatcagg acgatacgct gttccccaat
    44281 caatttgtga acgcccggat gctggtcgat accgaacaaa atgccgttgt ggtgcctgcc
    44341 gcggcggtgc aaatgggcaa tgagggccac tttgtgtggg tgctgaacga cgaaaataac
    44401 gtcagcaaga agcgggtaaa aatcggtatt caggataacc gaaacgtggt gatcagcgca
    44461 ggattgtcgg caggcgatcg cgtcgttacc gatggtattg atcggctgac ggaaggcgca
    44521 aaagtcgagg tcgttgagcc gcaaaccacc atggcggatg aaaaatcccc ttcccgccat
    44581 gaaggtcaaa aaggagcgcg cgcctgatgc aggtattacc tccgggcagc acgggcggcc
    44641 cttcgcgtct gtttattctg cgccccgtgg ccaccactct gctgatggcg gcgattttac
    44701 tcgccgggat tatcggctat cgcttcctgc ccgtcgccgc tttgccggag gtcgactacc
    44761 ccactattca ggtggttacg ctctaccctg gcgccagccc ggatgtcatg acctcctccg
    44821 tcaccgcgcc gcttgagcgc cagttcggcc agatgtcagg acttaagcag atgtcgtcgc
    44881 aaagctccgg cggcgcatcg gtggtgacgc tacagtttca gttgacgctg ccgctggacg
    44941 ttgccgagca ggaagtacag gcggcgatta acgcagccac caatttattg ccttccgacc
    45001 tgccgaatcc gccgatttat agcaaagtca atccggcgga cccgccgatt atgacgcttg
    45061 ccgtcacctc aaacgcgatg ccgatgaccc aggtagagga catggtagaa acccgcgtgg
    45121 cgcagaagat ctcacaggtc tccggcgtcg ggctggtgac gcttgccggc gggcagcgcc
    45181 ctgcggtacg cgtaaaactg aatgctcagg ctatcgccgc gctcggtctg accagcgaaa
    45241 cagtccgtac cgcaattacc ggcgccaacg tcaactcggc gaaaggcagt ctggatggcc
    45301 ccgaacgggc ggtgacgctt tctgctaacg atcagatgca gtctgccgac gaataccgca
    45361 agcttatcat cgcgtatcaa aacggcgcgc cggtacggct gggcgatgtc gccaccgtcg
    45421 aacagggggc ggaaaatagc tggctcggcg catgggcgaa tcaagctccg gctatcgtga
    45481 tgaacgttca acgccagccc ggcgccaata tcattgcgac agcggacagc attcgccaga
    45541 tgctgcccca gcttaccgaa agcctgccga aatcggtgaa ggtcacggtc ctgtccgatc
    45601 gcaccaccaa tattcgcgct tccgtgcgcg atacccagtt tgaactgatg ctggcgatcg
    45661 cgctggtcgt catgattatc tatctgtttt tacgtaatat tcccgccaca attattcccg
    45721 gcgtcgccgt accgctgtcg cttatcggca cctttgcagt gatggtgttt ttggattttt
    45781 ccattaataa cctgacgctg atggcgctca ctatcgccac gggtttcgtg gtggacgatg
    45841 cgattgtggt gatcgagaac atctcgcgct acatcgaaaa aggagaaaaa ccgctggcgg
    45901 cggcgctcaa aggcgcgggc gaaatcggct ttaccattat ttccctcacc ttttccctga
    45961 ttgcggtact gatcccgttg ctctttatgg gcgatattgt tggtcgactg ttccgcgaat
    46021 ttgcggtgac gttggcggta gcgattttaa tctccgccgt cgtctctttg acgcttacgc
    46081 ccatgatgtg cgcgcgtatg ctcagccggc agtctctgcg taaacaaaac cgcttttccc
    46141 gcgcctgcga gcggatgttt gaccgcgtga tcgccagcta cggacgcgga ttagcgaaag
    46201 tgctcaacca tccatggctt acattgagcg tggcattcgc cacgctcctg ctcagcgtta
    46261 tgctgtggat aaccatcccg aaagggttct ttccggtaca ggataacggc attatccagg
    46321 ggacgctgca ggcgccacaa tcatcatcgt atgccagtat ggcgcaacgt cagcgccagg
    46381 tggcggagcg gatattacag gacccggcgg tgcaaagcct gacgactttt gttggcgtag
    46441 acggcgctaa tcccacgctg aatagcgcgc gcctgcaaat taacctcaag ccgctggatg
    46501 cgcgtgatga ccgcgtgcag caggtgatct cccggctgca aaccgccgtg gcgacgattc
    46561 ccggcgtggc gctgtatctc cagccgacgc aggatttaac catcgacacg caggtcagcc
    46621 gcacgcagta tcagtttacc ctgcaggcca cgacgctcga tgcgctcagc cactgggtgc
    46681 caaaactgca gaacgcgcta cagtcgttac cacagctctc tgaggtaagc agcgactggc
    46741 aagatcgggg attagcggcc tgggtgaatg tcgaccgcga cagcgccagc cgtctgggta
    46801 tcagcatggc ggatgtggat aacgcgctct acaacgcgtt cggacaacgc ctgatttcaa
    46861 cgatttatac ccaggcgaac cagtaccgcg tcgtgctgga acataatacc gccagcacgc
    46921 cgggtctggc ggcgctggag acgattcgcc tgacgagccg cgacggcggc accgtaccgc
    46981 tcagcgcgat tgcccgcatt gagcagcgct tcgccccgct ctccatcaat catttagatc
    47041 agttcccggt tacgacattt tcgtttaacg tgccggaggg ctattcgctc ggcgatgcgg
    47101 tgcaggcgat tctcgatacg gaaaaaacgc tcgccctgcc agcggatatt acaacgcagt
    47161 ttcagggcag tacgctcgcc ttccaggcgg cgctgggcag caccgtctgg cttattgtcg
    47221 ccgccgtggt ggcgatgtat atcgtgcttg gcgtgctgta tgagagtttt atccatccga
    47281 ttacgattct ctcaacgctg cctacggcgg gcgtcggcgc gctgctggcg ctgatcatcg
    47341 ctggtagcga gctcgatatt atcgccatta tcggcattat tttactgatc ggtatcgtga
    47401 agaaaaacgc catcatgatg attgacttcg ccctcgccgc cgaacgcgaa caggggatga
    47461 gtccgcgcga cgctatcttc caggcctgtc tgctgcgttt tcgaccgatt ctgatgacca
    47521 cgctggcggc gttgctcggg gcattgccat taatgttgag taccggcgtt ggcgcggaat
    47581 tacgtcgccc gttggggatc gcgatggtgg gcggcttact ggtcagccag gtattaactc
    47641 tgtttaccac tccggtgatt tatctcctgt ttgaccgcct gtcgctgtac gtgaaaagtc
    47701 gctttccgcg ccataaagag gaggcgtaga tgcgcttttt cgcccttttc atctaccgcc
    47761 cggtcgccac cattttgatt gccgccgcca ttacgctgtg cggcattctg ggctttcgtc
    47821 tgctgccggt cgccccgctg ccgcaggtcg atttcccagt gattatggtt agcgcctcgc
    47881 tgccgggcgc ctcgccggaa accatggctt cgtcggtggc gacgccgttg gaacgttctt
    47941 tgggacgcat tgcaggcgtc aatgaaatga cttccagcag ctcgctcggc agtacgcgca
    48001 ttattctcga atttaatttc gatcgcgata ttaacggcgc ggcgcgcgac gtgcaggccg
    48061 ccattaacgc cgcgcaaagc ttgttgccag gcggaatgcc cagccgcccg acttatcgca
    48121 aggccaaccc gtccgacgcg ccgattatga ttttaacgct cacctcagag agctggtcac
    48181 agggcaaact gtatgatttc gcctctaccc aactggcgca aaccatcgcg caaattgacg
    48241 gcgttggcga cgttgacgtc ggcggcagct ccctgcccgc agtacgtgta ggcttaaacc
    48301 cgcaggcgct ctttaaccag ggcgtctcgc tggatgaggt ccgcgaagcg atcgacagcg
    48361 ccaacgtacg ccgaccgcaa ggcgcaattg aagatagcgt ccaccgctgg caaatccaga
    48421 ccaacgacga actgaaaacc gccgccgaat atcagccgct gattattcac tataacaacg
    48481 gcgcggcggt acgcctgggt gacgtcgcca gcgtcaccga ctcggtgcag gatgtccgta
    48541 acgccgggat gacgaacgct aaacccgcta ttttgttgat gatccgcaag ctgccggagg
    48601 ccaacattat tcagacggtc gacggcatcc gggcaaaact gccggaactg cgggcaatga
    48661 tccccgccgc tatcgattta caaatcgccc aggatcgttc gccgacgatt cgcgcatcgc
    48721 tgcaagaggt agaagagacg ctggctatct ctgtcgcgct ggtgatcctg gtggtgtttt
    48781 tattcctgcg ttccgggcgc gccacgctaa tccccgccgt cgccgttccc gtttcgctca
    48841 tcggcacctt cgccgccatg tatctgtgcg gcttcagcct caacaatctg tcgctgatgg
    48901 cgctgactat cgcgaccgga tttgtcgttg atgatgccat tgtggtgctg gaaaatatcg
    48961 cccgccatct ggaggcgaga atgaaacctt tgcaggcggc attacagggt acgcgggaag
    49021 tcgggtttac ggtcatctcc atgagtctgt cgctggtggc ggtatttctg ccgctgctgt
    49081 taatgggcgg cctgccagga cgattattac gggaattcgc cgttaccctc tcggtggcga
    49141 ttggcatttc gctggtggtc tcgctcacac tgacgccgat gatgtgcggc tggatgctta
    49201 aatcaagcaa accgcgcacc caaccgcgta aacggggcgt tggccgtttg ctggtcgcct
    49261 tgcaacaggg ttacggcacg tcgttaaaat gggtgcttaa ccatacgcgt cttgtcggtg
    49321 tggtttttct tggcaccgtt gcgctgaaca tctggcttta tatcgccatc cctaaaacat
    49381 tctttccgga gcaggacacc ggcgtgttga tgggcggtat tcaggctgac cagagcatct
    49441 ctttccaagc catgcgcggc aagctgcagg attttatgaa aattattcgc gacgatccgg
    49501 cggtgaataa tgtcactggt tttaccggcg gatcgagggt gaatagcggc atgatgttta
    49561 ttacgctgaa gccgcgcggc gaacgcaaag agacggcgca gcaagtcatt gaccgactgc
    49621 gggtcaaact ggcaaaagaa cccggcgcca agctgtttct gatggcggta caggatattc
    49681 gcgtcggcgg gcggcaggct aacgccagtt accaatatac gttgctgtct gactccctgc
    49741 cggcgctgcg cgagtgggag ccgaaaatac gcaaagcgct ctcggccctg ccgcaactgg
    49801 cggacgtaaa ctccgaccag caggataacg gcgcggagat gaaccttatc tacgaccgcg
    49861 acaccatgtc acggctgggc attgatgttc aggccgcaaa cagcctgtta aataacgctt
    49921 tcggccagcg gcaaatttcc accatttatc agccgatgaa ccagtataaa gtggtgatgg
    49981 aagtcgatcc gcgctatagc caggatatca gcgcgctgga gaaaatgttc gttatcaacc
    50041 gcgacggaaa agcgattcct ctctcttatt tcgcccaatg gcggcccgcc aatgcgccgc
    50101 tgtcggtaaa ccatcaggga ctttccgcag cgtccacgat tgcctttaac ttgccgaccg
    50161 gcacatcgtt atcgcaggcg acggaggcca ttgatcgcac catgacgcag cttggcgtcc
    50221 cctcgacggt acgcggcagt ttttccggaa cggcgcaagt cttccagcag accatgaatt
    50281 cacagcttat tttgatagtg gcggcgatcg ctaccgtcta cattgtgctg gggatactgt
    50341 acgaaagcta cgtccatccg ctgaccattc tctctactct gccatcggcg ggcgttgggg
    50401 cgcttctggc gctggaactc ttcaatgccc ctttcagcct aatcgccctg atagggatca
    50461 tgctattaat tggcattgtg aagaaaaacg ccattatgat ggtcgatttt gcgcttgaag
    50521 cgcaacgaag cggcggcctg acaccggaac aagccatttt ccaggcctgc ttgttacgct
    50581 tccgtccaat aatgatgacc acgctggcgg cgctgttcgg cgcactgcca ttggtgttat
    50641 ctggcggaga cggttcggaa ttacggcagc cgctggggat aaccattgtc ggcggtttgg
    50701 tcatgagcca gctcctgacg ctctatacca cgccggtggt gtacctcttt ttcgaccgtc
    50761 tgcggctgcg tttttcgcgt aaaaatagca aaccggtagt agagatatga cagaatttcc
    50821 tgacaacacc cgctggcaac tctggattgt ggcattcggc ttttttatgc agtcgctgga
    50881 taccaccatc gtcaacactg cgctgccttc catggcgaaa agcctggggg aaagcccgct
    50941 gcatatgcac atggtagtgg tgtcatatgt tctcaccgtc gccgtgatgc tccccgccag
    51001 cggctggctg gcagacaaaa tcggcgtgcg taatattttc tttgccgcca tcgtgctgtt
    51061 cacgctgggt tcgctgtttt gcgccctctc cggtacgctt aatcaactgg tattagcgcg
    51121 agttttacaa ggcgtaggcg gcgcgatgat ggtgccggtc ggacgcctga cggtcatgaa
    51181 aatcgtgccg cgtgcgcaat atatggcggc gatgaccttc gtcgccctac cgggacagat
    51241 cgggccgtta ctcggccccg cgctgggcgg ggtgctggtg gaatatgctt catggcactg
    51301 gatctttctg atcaatatcc cggtgggaat tgtcggcgct atggcgacct ttatgctgat
    51361 gccaaactac accatagaga cccggcgctt tgatctgccg gggttcctgc tgttagctat
    51421 cggcatggcg gtactcacgc tggcgctgga cggtagtaaa agcatgggga tttcgccctg
    51481 gacattagcc ggacttgctg cgggtggcgc ggcagccatt ctgctctatc tcttccatgc
    51541 caaaaaaaac tcaggtgcgt tattcagcct gcgattgttc cgcacgccca cgttttcact
    51601 ggggttgctg ggcagttttg ccgggcgtat cggcagcggt atgctgccgt ttatgacgcc
    51661 ggtcttttta caaattggtc ttggtttttc accgtttcat gccggtttga tgatgatccc
    51721 catggtgctg ggcagcatgg gaatgaagcg gattgtggtg cagatagtta accgttttgg
    51781 ctatcgtcgg gttctggtag cgaccacgct cggactggca ttggttagcc tgttgtttat
    51841 gtcggtcgcg ctgctcggct ggtattatct cctgccgctg gtactgcttt tgcagggaat
    51901 ggtgaactcg gcgcgctttt cttccatgaa taccttaacg ctaaaagacc ttcccgatac
    51961 gctggccagc agcggcaata gcttattatc gatgattatg cagctctcga tgagtattgg
    52021 cgtcactatt gccggaatgc tgctgggtat gtttggccaa cagcatatcg ggatagacag
    52081 tagcgccaca catcacgtct ttatgtacac ctggttatgt atggcggtta ttatcgcgct
    52141 accggcgata atttttgccc gcgtgccgaa cgatacacag caaaacatgg tcatttcacg
    52201 gcgtaaaagg agcctgtaat gaaagtctgg cggcccggaa tcaccggcaa gctgtttctg
    52261 gcgattttcg ccacctgcat cgtgctgctg atcagtatgc attgggccgt gcgcgtcagt
    52321 tttgaacgcg gatttattga ctatatcaaa cacggcaacg agcagcggct acaaatgctg
    52381 ggcgatgcgc tgggcgacca gtaccagcaa cacggcaact ggcgtttttt acgtaacaat
    52441 gatcgcttcg ttttccagat tctgcgttca tttgagcatg acaacgaccg ggataaaccc
    52501 ggccccggta tgccgccgca cggttggcgc acccagttct gggtcgtcga tcaaaatggc
    52561 cgggtgctgg tcggcccacg cggtccggtg ccgcatgacg gtactcgccg ccccattctg
    52621 gttaatggcg tcgaagtagg cgcgattatc gcctctcctg tcgagcggct gacgcgcaat
    52681 acggatatta attttgatat gcagcagcgg cgtgccagtt ggatgatcgt ggcgttatca
    52741 accttgctgg ccgcgctggc gacgtttttg ctggcgcgtg gcctgctcgc cccggtcaaa
    52801 cggttggtcg agggtacgca caggctggcg gcgggggatt ttaccacgcg cgtgacccca
    52861 accagcgccg atgagctggg aaaactggcg caagacttta accagcttgc cagcacgctg
    52921 gaaaaaaatc agcagatgcg ccgcgacttt atggcggata tttcccacga actgcgcacg
    52981 ccgctggcgg tattgcgcgg cgaactggaa gccattcagg atggcgttcg ccagttcacg
    53041 ccagaatcgg ttacctcgct acaggcggaa gtcggtacgc ttaccaaact ggttgacgac
    53101 ctgcatcagc tgtcgttgtc tgacgagggc gcgctggctt accaaaaaac gaccgtcgat
    53161 cttgttcccc agttggaagt cgctggcggc gcgtttagag aacgctttac cagccggggg
    53221 ctaacgctac attacgcgtt gccggatagt atgaccgtct tcggcgaccc ggatcgcctg
    53281 atgcaactgt ttaataatct actggaaaac agtctgcgct acaccgacag cggcggcggc
    53341 ctgcatattt ccgccgaaca acgcgacaaa tcattattcc tgacctttgc cgattctgca
    53401 ccgggcgtca gcgatgagca gttacaaaag ctttttgacc gtttttaccg cacggaagtg
    53461 tcccgtaacc gcgccagcgg cggttctgga ctggggctgg cgatatgcgt caatattgta
    53521 cacgcgcata acggtcatct tcacgccgct cattcgcctt ttggcggggt tagcattaca
    53581 gtagagttac cgctggatcg cgatttacag agagaagtat gactgaatta cccattgatg
    53641 aaaacacgcc gcgcattttg attgttgaag atgaacccaa gctgggacag ctgcttattg
    53701 actacttacg cgcggcgagt tacgccccca cgctcatcaa tcatggcgac aaggtactgc
    53761 cgtatgtgcg tcaaacgccg ccggatctga tcctgctgga tctgatgctg ccgggtatcg
    53821 atggtctgac gctatgccgg gagattcgcc gtttttccga catccccatt gtgatggtca
    53881 cggccaaaat tgaagagatc gaccggctgc ttgggctgga aatcggcgcc gatgattata
    53941 tctgtaagcc ttacagccca cgcgaagtcg tggcccgcgt gaaaaccatt ttgcgccgct
    54001 gtaaaccgca gcgcgaactc cagcagcagg atgccgaaag cccgttaatg attgatgaaa
    54061 gccgctttca ggcctcctgg tgtggtaaag cgctggattt aacccccgct gaattccgtc
    54121 tgctaaaaac cttatcgctt gaaccgggta aagttttttc ccgcgagcag ttgttaaacc
    54181 acctctacga cgactaccgt gtggtgaccg atcgtactat cgacagccac attaaaaacc
    54241 tgcgccgtaa actggaatcg ctggatgccg aacagtcatt tatacgcgcg gtctacgggg
    54301 tgggatatcg ctgggaagcg gatgcgtgtc gcctggtata atgattattg gcataacaat
    54361 aacaaggtcg taagacgata ttttccgcca acgctattct ggcggaatta acacactgcc
    54421 ctctttcatt tggccgagcg gtatcccgaa aaccacgacg aacgcgatcg gggacaa
//
LOCUS       DAJVKX010000013        53275 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000013 DAJVKX010000000
VERSION     DAJVKX010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 53275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53275
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.013"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(137..616)
                     /gene="folK"
                     /locus_tag="OPY25_000740"
     CDS             complement(137..616)
                     /gene="folK"
                     /locus_tag="OPY25_000740"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HCS0926428.1"
                     /translation="MTIAYIALGSNLASPLEQVNAALKAIADIPDSRIVAVSSFYRTP
                     PLGPQDQPDYLNAAVALDTALAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GDEVINTDRLTVPHYDMKNRGFMLWPLFEIAPELVFPDDKGLLIELMSQMSPCPDRW"
     gene            complement(613..2031)
                     /gene="pcnB"
                     /locus_tag="OPY25_000741"
     CDS             complement(613..2031)
                     /gene="pcnB"
                     /locus_tag="OPY25_000741"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HCS0926429.1"
                     /translation="MTLPRCAIFTRVANFCRKVLSREESEAEQAVARPHMTIIPREQH
                     AISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNATPDQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHNEGSESDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLQEGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLNMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGNGFETYQQLREY
                     HLFQPLFPTITRYFTENGDSAMERIIAQVLKNTDNRIRNEMRVNPAFLFAAMFWYPLL
                     EMAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLMEHPKFRAAFDLLELRAQVENNTELQRLAQWWAEFQASAPPEQKGMLNELDD
                     DPAPRRRRSRPRKRAPRREGTV"
     gene            complement(2172..3068)
                     /gene="gluQRS"
                     /locus_tag="OPY25_000742"
     CDS             complement(2172..3068)
                     /gene="gluQRS"
                     /locus_tag="OPY25_000742"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HCS0926430.1"
                     /translation="MTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQRGVWRVRI
                     EDIDPPREVPGAAATILRQLEHYGLHWDGEVLWQSQRHEAYREALAWLHEQGLSYYCT
                     CPRSRIQRLGGIYDGHCRTLCHGPENAAVRIKQQHPVMHFHDALRGDIQADPQLASED
                     FIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQLSLYKQFGWRAPGYVHL
                     PLALNEQGAKLSKQNHAPALATGDPRPVLVQALRFLGQRDVVAWQEMSVEELLRFAVA
                     HWRLTAVPTSANVNPAFSNASR"
     gene            complement(3137..3592)
                     /gene="dksA"
                     /locus_tag="OPY25_000743"
     CDS             complement(3137..3592)
                     /gene="dksA"
                     /locus_tag="OPY25_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HCS0926431.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLSHFKRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3769..4473)
                     /gene="sfsA"
                     /locus_tag="OPY25_000744"
     CDS             complement(3769..4473)
                     /gene="sfsA"
                     /locus_tag="OPY25_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCS0926432.1"
                     /translation="MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGC
                     ATPGDTVWYSTSENTKRKYPHTWELTETQSGAFICVNTLRANQLTKEAIQENRLPALA
                     GYNILNSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKH
                     LRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAE
                     LSATKMELNEPVPITL"
     gene            complement(4490..5020)
                     /gene="thpR"
                     /locus_tag="OPY25_000745"
     CDS             complement(4490..5020)
                     /gene="thpR"
                     /locus_tag="OPY25_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HCS0926433.1"
                     /translation="MSEPKRLFFAIDLPDDARAQIIAWRAAHFASEDGRPVAAANLHL
                     TLAFLGDVSNDKQRALAQLAGRIRQPGFTLHLDDAGQWLRSRVVWLGMRQPPRGLLQL
                     ANMLRAQAARSGCYQSPQPFHPHITLLRDASHTVAIPPPGFCWSFPVTSFALYASSYG
                     QGRTRYAELQRWTLGE"
     gene            5093..7522
                     /gene="hrpB"
                     /locus_tag="OPY25_000746"
     CDS             5093..7522
                     /gene="hrpB"
                     /locus_tag="OPY25_000746"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HCS0926434.1"
                     /translation="MTSLPVAAVLPELLTALKTAPQVLLSAPTGAGKSTWLPLQLLQQ
                     GPVAGKILLLEPRRLAARNVAQRLAEALNEKPGETVGYRMRAQSCVGPRTRLEVVTEG
                     VLTRMIQRDPELRGVGLVILDEFHERSLQADLALALLLDIQQGLRDDLRLLIMSATLD
                     NDRLCQRLPDAPTIVSEGRAFPVERRYQPLAAHLRFDEAVAMATAELLRNENGSLLLF
                     LPGVGEIQRVHEHLASRVGSDVLLCPLYGALSLEAQRKAIVPAPAGMRKVVLATNIAE
                     TSLTIEGIRLVVDSAQERVARFDARTGLTRLVTQRISQASMTQRAGRAGRLAPGICLH
                     LLAKEQAERAAAQSDPEILHSDLSGLLMEVLQWGCHDPASLFWLDRPPEVNLQAARRL
                     LLMLGALEGERLSARGRKMAATGNDPRLAAMLVNADEGDSAATAAMLAAILEDPPRGG
                     GTDLSVLFSRRQPGWQQRSQQLLKRLQVRNGEPDSALIMPLLARAFSDRIARRRGQEG
                     RYQLANGMGAMLDADDALGRHEWLIAPLLLQGSASPDARILLAQPLDIASLIQACPDL
                     LRQSDTVEWDEAQGTLKAWRRMRIGQLTVSVQPLAKPSEEELHQAMLNGIRDKGLSVL
                     NWTPEAEQFRLRLHCAAKWLPEYDWPAVDEASLLATLENWLLPHMTGVQSLRSLKSLN
                     VTQALRGLLDYAMLQRLDSELPGHYTVPTGSRITIRYHEDNPPALAVRMQEMFGEAST
                     PTLAQGRVPLVLELLSPAQRPLQITRDLSAFWQGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            7663..10185
                     /gene="mrcB"
                     /locus_tag="OPY25_000747"
     CDS             7663..10185
                     /gene="mrcB"
                     /locus_tag="OPY25_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HCS0926435.1"
                     /translation="MAGNDREPIGRKGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMP
                     RKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGVYLDQKIRSRIDGKVWQLPAAVY
                     GRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSK
                     EGQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPD
                     LLVDTLLATEDRRFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSE
                     RSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPV
                     EELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSAR
                     PLGVQPRGGVISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVV
                     EGIPALKKQRKLSDLETAMVVVDRFSGEVRAMVGGAEPQYAGYNRAMQARRSIGSLAK
                     PATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPENDDRRYSESGKVMLVDALTR
                     SMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIA
                     SGGNRAPLSALRSVIAEDGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLG
                     AKYPGLHLVGKTGTTNNNVDTWFAGIDGSQVTITWVGRDNNQPTKLYGASGAMAIYQR
                     YLANQTPTPLVLTPPEDVVDMGVDYDGNFVCNGGMRTLPVWTDDPNTLCQQGEMMQQQ
                     QQPSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN"
     gene            10478..12669
                     /gene="fhuA"
                     /locus_tag="OPY25_000748"
                     /pseudo
     CDS             10478..12669
                     /gene="fhuA"
                     /locus_tag="OPY25_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459196.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
     gene            12718..13515
                     /gene="fhuC"
                     /locus_tag="OPY25_000749"
     CDS             12718..13515
                     /gene="fhuC"
                     /locus_tag="OPY25_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HCS0926436.1"
                     /translation="MQENHIHSDTTFALRSVAFRVPGRTLLHPLSLTFPAGRVTGLIG
                     HNGSGKSTLLKMLGRHQLPSEGDILLDNQPLASWSSKAFARKVAYLPQQLPQAEGMTV
                     RELVAIGRYPWHGALGRFGVADREKVDEAITLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQQRGLTVVAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAELMRSDTLEQIYGIPMGILPHPAGAAPVSFVY"
     gene            13515..14405
                     /gene="fhuD"
                     /locus_tag="OPY25_000750"
     CDS             13515..14405
                     /gene="fhuD"
                     /locus_tag="OPY25_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HCS0926437.1"
                     /translation="MRELYPLTRRRLLTAMALSPLLWQMNTAQAAAIDPRRIVALEWL
                     PVELLLALGITPYGVADVPNYKLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEKLARIAPGRGFDFSDGKKPLAVARRSLVELAQTLNLEAAAEKHLAQYDR
                     FIASQKPRFIRRGGRPLLMTTLIDPRHMLVLGPNCLFQEVLDEYGIVNAWQGETNFWG
                     STAVSIDRLAMYKEADVICFDHGNSTDMNALMATPLWQAMSFVRAGRFHRVPAVWFYG
                     ATLSTMHFVRILNNVLGGKA"
     gene            14420..16459
                     /gene="fhuB"
                     /locus_tag="OPY25_000751"
     CDS             14420..16459
                     /gene="fhuB"
                     /locus_tag="OPY25_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016504759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HCS0926438.1"
                     /translation="MPDGGAKNALTDLRFGRFVGRIRRSRHPALLLLALLVAACWLTW
                     VNFSVALPRSQWQQAIWSPDIDIIEQMIFHYSQLPRLAISLLVGAGLGLVGVLFQQVL
                     RNPLAEPTTLGVATGAQLGITVTTLWAIPGALTTQFAALTGACIVGALVFGVAWGKRL
                     SPVTLILAGLVVSLYCGAINQLLVIFHHDQLQSMFLWSTGTLTQTDWSGVQRLWPQLL
                     GGVMLTLLLLRPMTLMGLDDGVARNLGLALSLARLAALSLAIVLSALLVNAVGIIGFI
                     GLFAPLLAKMLGARRLLARLMLAPLIGALILWLSDQIILWLTRVWMEVSTGSVTALIG
                     APLLLWLLPRLKSMSAPDMNASDRVAAERRHVLTFAVAGGALLLLATWVALSFGRDAH
                     GWTWASGTLLEELMPWRWPRILAALMAGVMLAVAGCIIQRLTGNPMASPEVLGISSGA
                     AFGVVLMLFLVPGNAFGWLLPAGSLGAAATLLIIMIAAGRGGFSPQRMLLAGMALSTA
                     FTMLLMMLQASGDPRMADVLTWISGSTYNATGGQVTRTAIVMVILLAVVPLCRRWLTI
                     LPLGGDAARAVGIALTPSRIALLALAACLTATATMTIGPLSFVGLMAPHIARMLGFRR
                     TMPHMVISALAGGVLLVFADWCGRMALFPYQIPAGLLSSFIGAPYFIYLLRKQSR"
     gene            complement(16550..17830)
                     /gene="hemL"
                     /locus_tag="OPY25_000752"
     CDS             complement(16550..17830)
                     /gene="hemL"
                     /locus_tag="OPY25_000752"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HCS0926439.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLTSVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEG
                     LLEAAEEANIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVY
                     LAPSAFEAGFMSVAHSMDDINNTIDAARRVFAKL"
     gene            18000..19421
                     /gene="clcA"
                     /locus_tag="OPY25_000753"
     CDS             18000..19421
                     /gene="clcA"
                     /locus_tag="OPY25_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HCS0926440.1"
                     /translation="MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILFMAAVVGT
                     LTGLVGVAFEKTVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAP
                     EAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGR
                     MVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAV
                     FTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRT
                     QDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSVGLLL
                     FIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIA
                     GMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILA
                     RTLAKQDAEQAAKNQNAPAGENT"
     gene            19503..19847
                     /gene="erpA"
                     /locus_tag="OPY25_000754"
     CDS             19503..19847
                     /gene="erpA"
                     /locus_tag="OPY25_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HCS0926441.1"
                     /translation="MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(19948..20571)
                     /locus_tag="OPY25_000755"
     CDS             complement(19948..20571)
                     /locus_tag="OPY25_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HCS0926442.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDNGPVFWVKDPTDLVVAMVTSMLTILLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFLAETGPLVAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAFYTFSVPLESASMMGMVVTLFIRLAAIRWHLKLPTFALDENGR"
     gene            complement(20608..21408)
                     /gene="btuF"
                     /locus_tag="OPY25_000756"
     CDS             complement(20608..21408)
                     /gene="btuF"
                     /locus_tag="OPY25_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HCS0926443.1"
                     /translation="MAKQMFRALGALLLTLPVWLYAAPRVITLSPANTELAFAAEITP
                     VGVSSYSDYPPEAQKIEQVSTWQGMNLERIVALKPDLVVAWRGGNAERQVNQLTSLGI
                     KVMWVDAVTIEQIADALRQLAAWSPQPEKAQQAAQTLLKEYAALKVEYAGKAKKRVFL
                     QFGMNPLFTSGKGSIQHQVLTTCGGENVFADSRVPWPQVSREQVLARHPQAIIVAGKA
                     GEILKIEQYWGNLLKIPVIPLNSDWFERASPRIILAAKQLCNALSQVN"
     gene            complement(21401..22099)
                     /gene="mtnN"
                     /locus_tag="OPY25_000757"
     CDS             complement(21401..22099)
                     /gene="mtnN"
                     /locus_tag="OPY25_000757"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCS0926444.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIDNRQTITLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAESCIRELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPDAVAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     TLMVETLVQKLAHG"
     gene            22184..23701
                     /gene="dgt"
                     /locus_tag="OPY25_000758"
     CDS             22184..23701
                     /gene="dgt"
                     /locus_tag="OPY25_000758"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HCS0926445.1"
                     /translation="MASIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKEQNRLEEYGLDAL
                     TGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTHDRCVVSSL
                     RLQEGEENLNDIRRKVRQDICHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGPVPDSHRYLMKKPGYYLSEEKYIARLRKELQLAPYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFSVEQLYHHLYHAWGHHEKDSLFELVVGNAWEKSRANTLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPQIFAGTFNQALLEDASGFSRLLELYKNVAVEHVFS
                     HPDVEQLELQGYRVISGLLDIYQPLLSLSLNDFRELVEKERLKRFPIESRLFQKLSTR
                     HRLAYVEVVSKLPTDSAEYPVLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            23831..25258
                     /gene="degP"
                     /locus_tag="OPY25_000759"
     CDS             23831..25258
                     /gene="degP"
                     /locus_tag="OPY25_000759"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HCS0926446.1"
                     /translation="MKKTTLAMSALALSLGLALSPLSATAAETSSSAMTAQQMPSLAP
                     MLEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQDGSPFQNSPFCQGGGNG
                     GNGGQQQKFMALGSGVIIDAAKGYVVTNNHVVDNASVIKVQLSDGRKFDAKVVGKDPR
                     SDIALIQIQNPKNLTAIKLADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLN
                     VENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKN
                     LTSQMVEYGQVKRGELGIMGTELSSELAKAMKVDAQRGAFVSQVMPNSSAAKAGIKAG
                     DVITSLNGKPISSFAALRAQVGTMPVGSKISLGLLREGKAITVNLELQQSSQSQVDSS
                     TIFSGIEGAEMSNKGQDKGVVVSSVKANSPAAQIGLKKGDVIIGANQQPVKNIAELRK
                     ILDSKPSVLALNIQRGDSSIYLLMQ"
     gene            25411..26568
                     /gene="cdaR"
                     /locus_tag="OPY25_000760"
     CDS             25411..26568
                     /gene="cdaR"
                     /locus_tag="OPY25_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HCS0926447.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDNAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPEHLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALVEWAQRLGIDL
                     NQPRVAAVVEVDSGQLGVDSAMAELQQLQNALTTPERNNLIAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLISRMKENGQLRFRVALGNYFTGPGSIARSYRTARTTMMVGKQ
                     RMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLVKLKAMDNNGLLRRTLTAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEQR"
     gene            complement(26657..27043)
                     /locus_tag="OPY25_000761"
     CDS             complement(26657..27043)
                     /locus_tag="OPY25_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HCS0926448.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDRGEFFAK
                     SVKFKYPRQRKTVVADGIGQGYKEVQEISPNLRYVIDELDQICQRDRSELDLKRKILD
                     DLRHLESVVANKISEIEADLDKLTRK"
     gene            27290..28592
                     /locus_tag="OPY25_000762"
                     /pseudo
     CDS             27290..28592
                     /locus_tag="OPY25_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459217.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
     gene            complement(28629..29453)
                     /gene="dapD"
                     /locus_tag="OPY25_000763"
     CDS             complement(28629..29453)
                     /gene="dapD"
                     /locus_tag="OPY25_000763"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HCS0926449.1"
                     /translation="MQQLQNVIETAFERRADITPANVDTVTREAVKQVISLLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIDGAESRYFDKAPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTKIYDRE
                     TGEVHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(29483..32155)
                     /gene="glnD"
                     /locus_tag="OPY25_000764"
     CDS             complement(29483..32155)
                     /gene="glnD"
                     /locus_tag="OPY25_000764"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HCS0926450.1"
                     /translation="MNTLPEQHANTALPTLPDQPQNPGVWPRAELTVAGIKARIDIFQ
                     HWLGEAFDSGICAEQLIEARTEFIDQLLQRLWIEAGFGQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDEQAQKVGELLTLLWDVKLDVGHSVRTLEECLLEGLSDLTVAT
                     NLIETRLLIGDVALFLALQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTPAECAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNDPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPVDDEFQLRGTLIDLRDDTLFIREPQAILRMFYMMVRNSAITGI
                     YSTTLRHLRHARRHLSQPLCYIPEARTLFLSMLRHPGAVSRGLLPMHRHSVLWAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFAKEETRQRHPLCVDLWPRLPHPELIL
                     IAALFHDIAKGRGGDHSVLGAQDVLTFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTETRLRFLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEAALHKIWTRCRANYFVRHSPNQLAW
                     HARHLLQHDLSQPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLAADRHDVIRTGLEQTITQHSWQPPQPRRQPAKLRHF
                     TVETEVNFLPTHTDRKSFMELIALDQPGLLARVGQIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNVLQLEVQQRLTAALNPNDKG"
     gene            complement(32268..33062)
                     /gene="map"
                     /locus_tag="OPY25_000765"
     CDS             complement(32268..33062)
                     /gene="map"
                     /locus_tag="OPY25_000765"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCS0926451.1"
                     /translation="MAISIKTSEDIEKMRVAGRLAAEVLEMIEPYIKPGVTTGELDRI
                     CNDYIVNEQHAISACLGYHGYPKSVCISINEVVCHGIPDDAKHLKDGDIVNIDVTVIK
                     DEFHGDTSKMFIVGKPTILGERLCRVTQESLYLGIKMVKPGIRLRTIGAAIQKYAEGE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDADDGGVVLQPGMTFTIEPMLNAGDYRIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTENGCEILTLRKDDTIPAIITHDE"
     gene            33512..34237
                     /gene="rpsB"
                     /locus_tag="OPY25_000766"
     CDS             33512..34237
                     /gene="rpsB"
                     /locus_tag="OPY25_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCS0926452.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKISARKGKILFVGTKRAASEAVKEAANSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVSLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            34495..35346
                     /gene="tsf"
                     /locus_tag="OPY25_000767"
     CDS             34495..35346
                     /gene="tsf"
                     /locus_tag="OPY25_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCS0926453.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNVAFILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVASLEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKQLAMHVAASKPEFVKPEDVSADVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKSVGQLLKEHNADVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            35491..36216
                     /gene="pyrH"
                     /locus_tag="OPY25_000768"
     CDS             35491..36216
                     /gene="pyrH"
                     /locus_tag="OPY25_000768"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCS0926454.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDNYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPSATMYDQLTYSEVLDKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            36363..36920
                     /gene="frr"
                     /locus_tag="OPY25_000769"
     CDS             36363..36920
                     /gene="frr"
                     /locus_tag="OPY25_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCS0926455.1"
                     /translation="MISDIRKDAEVRMEKCVEAFKTQISKVRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMGPAVEKAIMASDLGLNPSSAGTDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKAISEDDDRRSQEEV
                     QKMTDAAIKKVDAALADKEAELMQF"
     gene            37062..38258
                     /gene="ispC"
                     /locus_tag="OPY25_000770"
     CDS             37062..38258
                     /gene="ispC"
                     /locus_tag="OPY25_000770"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HCS0926456.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVHHNPDSFRVIALVAGKNVARMAE
                     QCLEFSPRYAVMDDTSSAEQLKIMLQQHGSRTEVLSGQQAACEMAALDEVGHVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDEVKRSNARLLPVDSEHNAIFQSL
                     PQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVTSGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLHEPASVDDVLQVDAIAREVARKQ
                     VIRLSR"
     gene            38571..39329
                     /gene="ispU"
                     /locus_tag="OPY25_000771"
                     /gene_synonym="uppS"
     CDS             38571..39329
                     /gene="ispU"
                     /locus_tag="OPY25_000771"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HCS0926457.1"
                     /translation="MLSATQPVSENLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIDALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDISRFNSRLQERIRKSEALTAHNTGLTLNIAANYGGRWDIVQGVRQLAEL
                     VQAGVLRPDQIDEERLGQQICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALHAFANRERRFGGTEPGDDKA"
     gene            39342..40199
                     /gene="cdsA"
                     /locus_tag="OPY25_000772"
     CDS             39342..40199
                     /gene="cdsA"
                     /locus_tag="OPY25_000772"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCS0926458.1"
                     /translation="MLKYRLISAFVLIPAVIAALFLLPPVGFAIITLVVCMLAAWEWG
                     QLSGFAARSQRVWLAVLCGLLLALMLFLLPEYHHNIRQPLVEMSLWASLGWWVVALLL
                     VLFYPGSAAIWRNSKTLRLIFGLLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLNVAPV
                     ILLICSVVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            40211..41563
                     /gene="rseP"
                     /locus_tag="OPY25_000773"
     CDS             40211..41563
                     /gene="rseP"
                     /locus_tag="OPY25_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HCS0926459.1"
                     /translation="MLSILWNLAAFIIALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDRYGTEYVIALIPLGGYVKMLDERAEPVAPELRRHAFNNKTVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVIGEITPNSIAAQAQIAPGTELKAVDGIETP
                     DWDAVRLQLVSKIGDQQTTVSVAPFGSDQRQDKTLDLRHWAFEPDKQDPVSSLGIRPR
                     GPQIEPVLSEVQANSAASKAGLQAGDRIVKVDGQPLTQWMKFVTFVRDNPGKPLALEI
                     ERQGSALSLTLTPDTKSVNGKAEGFAGVVPKIIPLPEEYKTIRQYGPFSAILEATDKT
                     WQLMKLTVNMLGKLITGDVKLNNLSGPISIAQGAGMSAEFGVIYYLMFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKLKGGPVSERVQDFSYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            41595..44006
                     /gene="bamA"
                     /locus_tag="OPY25_000774"
     CDS             41595..44006
                     /gene="bamA"
                     /locus_tag="OPY25_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HCS0926460.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGNTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTLSDIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAKIQQINIVGNHAFSTEELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITVNITEGDQYKLSGVQVSGN
                     LAGHSAEIEKLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSQPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDSVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYSVGINGTKNDYQTYSELSVTNPYFTVDGVSLGGRIFYNDFEADDADLSDYTNKS
                     YGTDVTLGFPINEYNTLRAGLGYVHNKLSNMQPQIAMDRYLESMGDPDASDFAADDFT
                     FNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVSLDTATYVPIDNDHKWVV
                     LGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYKNGAHTSWDDDDD
                     YEDCTQESGCKSDDAVGGNAMAVASLEFITPTPFISEKYANSVRTSFFWDMGTVWDTN
                     WDPSSAPSDVPDYSDPGNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFN
                     IGKTW"
     gene            44129..44614
                     /gene="skp"
                     /locus_tag="OPY25_000775"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             44129..44614
                     /gene="skp"
                     /locus_tag="OPY25_000775"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HCS0926461.1"
                     /translation="MKKWLLAAGLGLAMVTSAQAADKIAIVNMGNLFQQVAQKTGVSN
                     TLENEFKGRAAELQKMETDLQSKMQRLQSMKAGSDRTKLEKDVMSQRQTFAQKAQAFE
                     KDRARRSNEERNKLVTRIQTAVKKVANDQSIDLVVDANTVAYNSSDVKDITADVLKQV
                     K"
     gene            44618..45643
                     /gene="lpxD"
                     /locus_tag="OPY25_000776"
     CDS             44618..45643
                     /gene="lpxD"
                     /locus_tag="OPY25_000776"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HCS0926462.1"
                     /translation="MPSIRLADLAEQLDAELHGDGDIVITGVASMQSATTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATATLGSNVSVGANAVIESGVQLGDNVVIGAGCFVGKNSKIGAGSRLWANVTI
                     YHDIQIGENCLIQSSTVIGADGFGYANDRGNWVKIPQLGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKAIE
                     RKVNQQD"
     gene            45749..46204
                     /gene="fabZ"
                     /locus_tag="OPY25_000777"
     CDS             45749..46204
                     /gene="fabZ"
                     /locus_tag="OPY25_000777"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCS0926463.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            46208..46996
                     /gene="lpxA"
                     /locus_tag="OPY25_000778"
     CDS             46208..46996
                     /gene="lpxA"
                     /locus_tag="OPY25_000778"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HCS0926464.1"
                     /translation="MIDKSVFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVL
                     KSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNA
                     YKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR"
     gene            46996..48144
                     /gene="lpxB"
                     /locus_tag="OPY25_000779"
     CDS             46996..48144
                     /gene="lpxB"
                     /locus_tag="OPY25_000779"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HCS0926465.1"
                     /translation="MAAQRPLTIALVAGETSGDILGAGLIRALKARVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTRRFTELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRSTHMVLAFLPFEKAFYDKFNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQRYPDLEVVVPLVNAKRREQFEKIKAEVAPDLAVHLLDGMAREAMIASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTEYVSLPNLLAGRELVKELLQEECEP
                     QKLAEALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAADAVLELAQ"
     gene            48141..48737
                     /gene="rnhB"
                     /locus_tag="OPY25_000780"
     CDS             48141..48737
                     /gene="rnhB"
                     /locus_tag="OPY25_000780"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCS0926466.1"
                     /translation="MIEFVYPHTHLVAGVDEVGRGPLVGAVVTAAVILDPARPIVGLN
                     DSKKLSEKRRLSLYDEIKEKALSWSLGRAEAHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPELPVPSMAVVKGDSRVAEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAQYGATAHHRRSFAPVKRALGLVS"
     gene            48761..52243
                     /gene="dnaE"
                     /locus_tag="OPY25_000781"
     CDS             48761..52243
                     /gene="dnaE"
                     /locus_tag="OPY25_000781"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCS0926467.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTGPLVKKAASLGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVHNELLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIERDWLVELKEGLILLSGGRMGDVGRCLLRGNQALVEECVAFYEA
                     HFPDRYFLELIRTGRQDEETYLHAAVELAEARGLPVVATNDVRFLESDDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFSDIPEALENTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMTTEDYLVKKSKEGLEERLAFLFPDEEERKKRRPEYDERLDIELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLVPPDPGMTLAKAFEAEPQLPEIYEADEEVRALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREELSYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFEEGAKKNGIDGEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDEGEIVYGIGAIKGVGEGPIEAIIDARNQG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVTTAAGLVIAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            52256..53215
                     /gene="accA"
                     /locus_tag="OPY25_000782"
     CDS             52256..53215
                     /gene="accA"
                     /locus_tag="OPY25_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCS0926468.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQVAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLEGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPVICTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLEDLADLDVLSTDDLKNRRYQRLMSYGYA"
BASE COUNT        11925 a        13432 c        15455 g        12463 t
ORIGIN      
        1 aaatatatgg tttgttacta tgttatataa tatacgactg gttccatgat tatttctaac
       61 aagagtattt aatttatcta attatacgga ataacagcat agaaactatt tgttgaattg
      121 ataatagggg tatttcttac caacgatcgg gacagggaga catttgggac atcagctcga
      181 tcagcagacc tttatcgtcg ggaaacacca gctccggagc gatttcgaat aacggccaca
      241 gcataaaacc gcggtttttc atgtcgtagt gcggcacggt cagacggtcg gtgttaatga
      301 cttcatcgcc aaacagcata atgtcgagat ccagcgtgcg cggcccccag cgttcggcct
      361 tgcgcacccg gccctgttgc agctcaatgc gctgggtatg gttaagcaat tcttcggggg
      421 cgagagcggt atccagcgcc accgcagcgt tcaggtaatc gggctgatcc tgtgggccaa
      481 gcggcggcgt gcggtaaaac gaagaaaccg cgacgatacg gctatcggga atgtcggcga
      541 tagccttcag ggcggcattg acctgctcca gcggagaggc cagattactg ccaagcgcga
      601 tatacgcgat cgtcatacgg tgccctcgcg gcgcggcgcg cgtttgcgcg gacgtgaacg
      661 acggcggcgt ggagcaggat cgtcgtccag ctcgttgagc atcccttttt gttccggcgg
      721 cgcggaagcc tgaaactcgg cccaccactg cgccagacgt tgcagttcag tattattttc
      781 cacttgggcg cgcagctcca gcaaatcaaa cgcggcgcgg aatttgggat gttccatcag
      841 cttccaggcg cgtttgccct ggcgtcgcga catgcgtaac tgaagctgcc aaatatcacg
      901 ggtaagcgtg gtaaggcgtt tcgggatcgc cagtgaacgg caggcttcat ccagcacgtc
      961 attcatggcc agcgcgaaag catcgtaata ggcaaggccg ctctcctgag cgattttttg
     1021 cgccatctcc agcagcggat accagaacat ggcggcaaac aaaaatgccg ggttaacgcg
     1081 catctcgtta cggatgcggt tatccgtatt cttcaacacc tgcgcaatga tgcgttccat
     1141 tgcgctgtcg ccgttttcgg tgaaataacg cgtaatggta ggaaacaacg gctggaagag
     1201 gtggtattcc cgcagttgtt gataggtttc aaaaccgttc cccgcctgca acagcttcag
     1261 cgattcttcg aacaggcgcg cgggaggaat gtcgtttagc aaggttgcca gacgcgggat
     1321 tggctcagcc gtttcagggc tgatacgcat attgagcttc gcagcgaaac gcacggcgcg
     1381 cagcattcga accggatctt cgcggtagcg cgtttccgga ttgccgatca ggcgaatcac
     1441 gccttcttgc agatcctgca tcccgccgac gtaatcgcgc acggtaaaat ccgccacgct
     1501 gtagtaaagg ctgttgatgg tgaaatcgcg gcgctgggca tcttcttcga tagagccgaa
     1561 gatgttgtcg cgcagcagca taccgttttg cccacgctgg gaggtcgtac ggtcgctttc
     1621 actgccttca ttatgaccac gaaacgttgc cacttcgata atttccgggc caaacatcac
     1681 gtgagccagg cggaaacgac gccccaccag acggcaattg cggaataatt tccgtacctg
     1741 atccggtgtt gcgttggtgg tcacatcgaa atccttcggc tttttaccga gcaggagatc
     1801 gcggacgccg ccgccgacca ggtaggcttc atagcccgct ttgttcagcc tgtacagtac
     1861 cttgagggca ttttcactga tatctttgcg ggagatagcg tgctgttcac gcgggataat
     1921 cgtcatatgt ggacgggcga cggcttgttc tgcctcgctc tcctcgcggc ttaacacctt
     1981 acggcaaaaa ttagcgactc gggtaaaaat agcgcacctc ggtagtgtca tacattaata
     2041 agatcaactt actctatgtc tttcgcatta cggcagacgg gcgtaagaga gcaacgcgac
     2101 ctgggctgta agcatcatta acgccgcagc aatgcgaaag acgatgagca aaaatagcgg
     2161 ctaatcatag ctcagcgaga cgcatttgag aatgccggat ttacattagc cgatgtgggt
     2221 acggctgtaa gcctccagtg cgccaccgca aagcgcagca actcctcaac agacatctcc
     2281 tgccacgcta cgacgtcgcg ttggcctaaa aagcgcaatg cctggaccag taccgggcgc
     2341 ggatcgcctg tcgcaagcgc aggggcatga ttttgcttgg aaagtttagc gccttgttcg
     2401 ttgagcgcca gcggaaggtg cacgtaacct ggcgcacgcc agccaaactg tttatacagc
     2461 gaaagttgtc ggacagtagg ttcgattaaa tctgcgccgc ggacgatctc cgtcaccccc
     2521 tgaaaatgat cgtcgaccac cacggccagg ttataagcaa acagtccgtc gcggcggtgg
     2581 ataataaaat cttcgctagc cagctgtggg tcagcctgga tgtcgccgcg caaggcatca
     2641 tggaaatgca tcactggatg ctgctgttta attctgacgg cggcattctc cggcccgtgg
     2701 cataacgtcc ggcaatggcc atcgtaaata ccgcccagac gttgaatgcg cgagcggggg
     2761 caagtgcagt agtagctcag tccctgctcg tgaagccagg ccagcgcctc gcgataagcc
     2821 tcatgacgct gtgattgcca taagacctcg ccatcccagt gcaggccgta atgttccagc
     2881 tggcgcagaa tggtcgctgc ggcaccggga acttcacgtg gggggtcgat atcctctatg
     2941 cgaacgcgcc aaactccgcg ttgcgcacgg gcttgtagat agctgccgag ggcggcgatt
     3001 aacgagccga aatgcagttc gccggatggc gacggcgcga aacggccaat atagtgtgag
     3061 tcagtcatgc tgcgggcaat aaagaataag gcgggaaaac tcccgcctgt cataaatagg
     3121 gtagaaacga acgggattaa cccgccatct gtttttcgcg aatttcagcc agcgttttgc
     3181 agtcgatgca cagatcggct gttggacgcg cttccaggcg gcggatacca atctccactc
     3241 cgcaggactc gcaataaccg aagtcttcat cttccacttt cttcagcgtt ttctcgatct
     3301 ttttgatcag tttgcgctca cggtcacgat tacgtaactc caggctaaac tcctcttcct
     3361 gcgcggcgcg atcgaccgga tcggggaagt tggcggcttc gtcctgcatg tgcgtcacag
     3421 tgcgatcgac ttcatcccgg agttgattac gccatgcttc aagaatacgc ttgaagtgcg
     3481 atagctgggc ttcgttcata tactcttcgc ccggtttctc ctggtacggc tccaccccag
     3541 cgatggcgag aatactcagg gacgatgttt tacggttttg cccttcttgc atgttgcttc
     3601 tccttaacac gcactatcga tccccatgtt cgggggaaaa tcaggtcgct ataaatagca
     3661 gatgcttttc cggatagcaa ttatctaaac gtaacacttg acaaccctgt gaggaaaagc
     3721 gtatttacgc acgcggccag aatacttaat aatcaggctg ttattccact acaacgttat
     3781 gggcactggt tcgttcagtt ccatttttgt ggctgaaagt tctgctttat aagctaaaac
     3841 ttccacgcct ttattctgag cctcgctcaa tagctgcgcg tattttatat cgatatgacg
     3901 tgcgggggaa aaacgtgtaa tggcggagtg cagcacagcg aacaccacca ccgcgcgatg
     3961 acctgccgcc gcaacgccca tcaactcccg aagatgtttt tgccctcgtt cggtgatggc
     4021 gtcgggaaaa taaccgtttt ctttttccgc taacgtgacc gatttcactt caatatagca
     4081 gtccgggcgg aaatctgcct gtaacataaa atctatacgg ctgcgctcgg cgccatattt
     4141 gacttcacta ttcagaatat tgtaccccgc cagcgccggc aggcgattct cctgaatcgc
     4201 ttctttcgtt agctggttcg cccgcagcgt attcacgcaa atgaatgcgc cggattgcgt
     4261 ttcagtcaat tcccaggtat gcggatattt gcgtttagta ttttctgatg tcgaatacca
     4321 gacggtatcg ccaggcgtgg cgcagccagt catcgcgccg gtattaggac agtgcagcgt
     4381 aagcgtcgta ccgtcagggg tgatgacatc agctaaaaaa cgtttatagc gctgaatcaa
     4441 cgtagcgcgt tgtaaagggg gtgagaatag catcgacatt ccttgattat tattcgccca
     4501 gcgtccagcg ctgcagctcg gcatagcggg tacggccttg cccatacgaa gaggcgtaaa
     4561 gcgcaaacga tgtgaccgga aatgaccagc aaaagcccgg cggcgggata gccaccgtat
     4621 ggctggcgtc gcgcagcagc gtaatatgcg ggtgaaaagg ctgcgggctt tggtaacaac
     4681 cgctgcgggc ggcctgcgcg cgcagcatat tagccaactg caacaacccg cgcggcggct
     4741 ggcgcattcc cagccacaca acgcgcgaac gcaaccactg accggcgtca tctagatgta
     4801 gcgtaaagcc cggttggcga attcgtccgg ccagttgcgc aagcgcgcgc tgcttatcgt
     4861 tactgacgtc gcctaaaaag gccagcgtca ggtgtaggtt cgccgctgcc acggggcgtc
     4921 cgtcttcaga cgcaaaatgg gcggcgcgcc aggcgataat ttgcgcgcgc gcgtcgtcgg
     4981 gtaagtcaat agcaaaaaac agccgttttg gctcagacat agggatactc ggttatggat
     5041 taacacgatg ctacaatgcg gcgcaaagaa agttaacccc gtggagccgt ttgtgacgtc
     5101 attgcccgtt gccgccgtat tgcctgaatt gttgacagcc ctaaaaaccg cgccgcaggt
     5161 tttgttgtcc gcgcctaccg gggcggggaa atccacctgg ctgccgttgc aactcctgca
     5221 acaggggccg gttgctggaa aaattctcct gcttgaaccg cgtcgtctgg cggcgcgtaa
     5281 tgtcgcccag cgtctggcgg aagcgttgaa tgaaaagcct ggcgaaacgg taggttaccg
     5341 gatgcgcgcg caaagctgcg tggggccgcg tacccggctg gaagtggtga ccgaaggcgt
     5401 attgaccaga atgattcagc gcgatcccga attacgcggc gtggggctgg tgatactgga
     5461 tgaatttcat gagcgcagtt tacaggcgga tttagcgttg gcgctgttgc tggatatcca
     5521 gcaagggctc cgtgacgatc tcaggctgtt aatcatgtct gcgacgctgg ataacgacag
     5581 gctttgtcag cgactgcctg atgcgccgac gatcgtctcg gaggggcgcg cgtttcccgt
     5641 ggagcgacgt tatcagccgc ttgcggcgca tttgcgtttt gatgaagccg tcgcgatggc
     5701 gacagcggaa ctgctgcgca atgaaaacgg ttcgctgctg ctatttttac ccggcgtagg
     5761 cgaaatacag cgcgttcatg aacatctggc gtcgcgggta gggagcgatg tcctgctttg
     5821 tccgctgtat ggcgcattgt ctctggaagc gcaacgcaaa gcgattgttc ccgcacccgc
     5881 cgggatgcgt aaagtggtat tggcgactaa cattgccgaa accagtttga cgattgaagg
     5941 gattcgtctg gtcgtcgata gcgctcagga gcgcgtggcg cgattcgacg cgcgaacggg
     6001 actgacgcgg ctggttacgc agcgtatcag tcaggcgtca atgacgcagc gcgcggggcg
     6061 cgccggacga ctggcgccgg gtatctgttt acatctgctg gcaaaagaac aggcggagcg
     6121 ggcggcggcg caaagcgatc cggaaatctt acacagcgac ctctccggtt tgttgatgga
     6181 ggtgttgcag tggggatgtc acgatccggc ctcgcttttc tggctggaca ggccgccgga
     6241 ggtgaatctt caggccgccc gccgtttatt attgatgtta ggcgcgctgg agggcgagcg
     6301 attaagcgcg cgggggcgga aaatggcggc aacaggtaac gatccgcgcc tggcggcgat
     6361 gttagtcaac gccgacgagg gcgacagcgc cgccactgcc gccatgctcg cggccatcct
     6421 tgaggacccg ccgcgaggcg gcggtacgga tttaagcgtg ctattttcgc ggcgacagcc
     6481 gggctggcag cagcgtagcc agcagctttt aaaacggctg caggtgcgta atggcgagcc
     6541 ggatagcgcg cttattatgc cgctgttggc cagagcgttt agcgaccgca tcgcgcggcg
     6601 tcgcggtcag gaagggcgct atcagttagc caatggtatg ggcgcgatgt tagatgcgga
     6661 tgacgcgttg ggacgtcatg aatggctgat cgcgccgctg ttactgcaag gtagcgcctc
     6721 gccggacgcc cgaatattgt tggcgcagcc gctggatatt gcctcgctga ttcaggcgtg
     6781 tcctgattta ctgcgccagt ccgacacggt tgaatgggac gaggcgcagg gaacgttgaa
     6841 agcatggcgc agaatgcgta ttggacagtt gacggttagc gttcagccac tggcgaagcc
     6901 gtctgaagag gagcttcatc aggcgatgct gaacggcatc cgcgataaag gtctgtccgt
     6961 ccttaactgg acgccggaag cggagcagtt ccgtctgcgt ctgcactgtg cggcgaaatg
     7021 gctgccggaa tatgactggc ctgccgtgga tgaggcgtcg ctgctggcga ctctggaaaa
     7081 ttggttgctg ccgcacatga caggcgtaca gtcgttacgg agtctgaaat ctctgaatgt
     7141 gactcaggcg ttacggggac tgcttgacta tgccatgctg caacgtctgg atagtgaact
     7201 gcctgggcat tacactgtgc cgacgggaag ccgaataacg attcgttatc atgaagataa
     7261 cccgcccgcg ctggcggtca gaatgcagga aatgttcggc gaggcaagta cgccgacact
     7321 tgcgcagggg cgagtgccgc tggtgctgga actgctttcg ccagcgcagc gaccgctaca
     7381 gattacgcgc gatttaagcg ctttctggca gggggcgtat cgcgaagtgc aaaaagagat
     7441 gaaggggcgt taccccaaac atgtctggcc ggacgatccg gcgaatacgg ctccaacgcg
     7501 gcgcacgaag aagtattcgt gacgtgttat acgttgcctc caggccggat aaggcgttaa
     7561 tcgccatccg gcaaaaaggt aaattgagag atttcttctt ctgtcgtctg gcggaagaat
     7621 agagaatcgg gcctttgcgc ctgtatgttg cggagaaaaa gcatggcggg gaatgaccgc
     7681 gagccgattg gacgtaaggg gaaaccgtca cgtcctgtga aacaaaaggt gagccgtcgt
     7741 cggcagcatg acgacgatta tgatgatgac tatgaggatg aagaaccgat gccgcgtaaa
     7801 ggtaagggca aagggcgtaa gcctcgtggc aagcgcggct ggctgtggct attgctaaaa
     7861 ctgtttatcg tttttgtggt gctgttcgcc atttacggcg tctatctgga tcaaaaaatc
     7921 cgcagccgta ttgatggcaa ggtctggcag cttccggcgg cggtatatgg ccggatggtg
     7981 aaccttgagc cagacatgcc tgtcagcaaa aacgagatgg tgaaattgct ggaagcgacg
     8041 cagtatcgtc tggtgacgaa gatgacccgt cccggcgaat ttaccgtgca ggccaatagc
     8101 attgagatga tccgtcgtcc gtttgacttc ccggacagca aagaagggca ggtgcgcgcg
     8161 cggctgacgt tcagtgacgg gcgtctggaa accatcgtca atctggataa caaccgccag
     8221 tttggcttct tccgcctcga tccgcggctt atcaccatgc tttcttcgcc aaatggcgag
     8281 cagcgtttat tcgtcccgcg cagcggtttc ccggatctgc tggtcgatac gctgttggcg
     8341 acggaagacc gtcgtttcta tgagcatgat ggcattagtc tttactctat cgggcgtgcg
     8401 gtgctggcca acctgacggc gggacgcacg gtgcaggggg ccagtacgct gacccagcag
     8461 ctggtgaaga acctgttcct ctccagcgaa agatcatact ggcgtaaagc gaatgaagcc
     8521 tacatggcgc tgatcatgga tgcccgttac agtaaagatc gtattcttga gctgtacatg
     8581 aacgaggtct acctcggtca aagcggggat aatgaaattc gcggttttcc gctggcgagc
     8641 ctgtattact ttggtcgtcc ggtagaggaa ctgagcctcg atcagcaggc gttactggtg
     8701 gggatggtaa aaggggcgtc gatttataac ccgtggcgta acccgaaact ggcgctggag
     8761 cgtcgtaacc tagtgttacg cctgttacag cagcagaaaa tcatcgatca ggaactctat
     8821 gacatgctga gcgcgcgtcc gcttggcgta cagccgcgcg gcggcgttat ttcaccgcag
     8881 ccagcgttta tgcagatggt tcgtcaggaa ctgcaggcga agctggggga taaaattaaa
     8941 gatctctccg gcgtgaagat cttcaccacc tttgactccg tggcgcagga tgccgcagaa
     9001 aaagccgttg tcgaaggcat tccggcgttg aagaagcagc gtaaattgag cgatctggaa
     9061 actgcgatgg tggtagtgga tcgctttagc ggcgaggtac gcgcgatggt tggcggggcg
     9121 gagccgcagt atgctggcta taaccgtgcc atgcaggcac gccgttccat cgggtcgctg
     9181 gcgaaaccgg cgacctatct gaccgcgtta agtcagccga acttataccg tctgaacacc
     9241 tggattgccg atgcgccgat ttctctgcgc cagccgaatg gtcaggtctg gtcgccggag
     9301 aacgacgatc gtcgctacag cgaaagcggg aaagtgatgc tggtggatgc gttaactcgt
     9361 tcaatgaacg taccgacggt caatctgggg atggcgttag gtttaccggc ggtaaccgat
     9421 acctggacga agctcggcgt gccgaaagat cagctcaatc cggttccggc gatgctgtta
     9481 ggggcgctga acctgacgcc gatcgaagtg gcgcaagcgt tccagactat cgccagcggc
     9541 ggaaatcgcg cgccgttatc agcgctgcgt tcggttattg cggaagatgg taaagtgctg
     9601 taccaaagtt atccgcaagc tgaacgcgcc gtaccggcac aggcggctta cctgacgctc
     9661 tggacaatgc agcaggtcgt ccagcgtggt acggggcgtc agcttggcgc gaaatatccg
     9721 ggtctgcatc tggtgggtaa aaccgggacg acaaacaaca atgtcgatac ctggtttgcc
     9781 ggtatcgacg gcagccaggt gactatcacc tgggtaggcc gtgataacaa ccagccaacg
     9841 aaattgtacg gtgccagcgg cgcgatggcg atttaccagc gctatctggc gaaccagacg
     9901 ccgacgcctt tagttctgac gccgccggaa gatgtggtgg atatgggcgt tgattacgac
     9961 ggtaattttg tctgtaacgg cggtatgcgc actctgccgg tctggacgga cgatccaaat
    10021 acgctgtgcc agcagggcga gatgatgcag cagcaacagc agccgtcagg caatccgttc
    10081 gatcagtcgt ctcagccgca gcagcctgcg cagcaacagc cgccgaaaga agagaagagc
    10141 gacggcgttg ccggctggat taaggagatg tttggcggca attaatcacg gtaatagtgc
    10201 cgggtggcgc tgtgcttact cggtccacac cgttacgacc ccattatgtg cgacgtaggc
    10261 cgaataagac gcttacatcg ccatccggca aatcctccat aaataacatt tcagtctaat
    10321 ttattaaccc ttccttttca tctggttgtt tcttaacccc ttagttttcg tagggccgcg
    10381 tatcgcttgc cattgcgacg atatttcgcc tatcatgctg cggttataat aataattatc
    10441 gtttacgtta tcattcactt tcatcagaga tataccaatg gcgcgtctta aaattgctca
    10501 gccaaactcc tcactgcgta aaatcgcagt tgtagtagcc acagcggtta gcggcatgtc
    10561 tgtctatgca caggcggcgg ttcaaccgaa agaagaaacc attaccgtaa ccgcagcgcc
    10621 tgcgccgcag gaaagtgcct ggggaccggc tccgaccatc gccgcgaagc gttccgccac
    10681 taccaccaaa actgatacat ctatcgaaaa aacgccacag tcggtttcgg tggtcactaa
    10741 cgaagagatg cagatgcatc aattccagtc agtaaaagaa gcgttgggtt acacgccggg
    10801 cgtaactgta agcagtcgcg gcgcttccaa tacctatgac ttcgtgatta tccgtggctt
    10861 ctcttccgtc ggcctgagcc agaataacta tctctggatg gcctgaaatt gcagggtaac
    10921 ttctacaacg atgcggttat tgatccatcc ctgcttgagc gtgttgagtt gatgcgtggc
    10981 ccaacgtccg ttctctatgg taagagcaac ccgggcggta tcatttcgat ggttagcaag
    11041 cggccgacta ctgagccgct gaaagaaatt caattcaaaa tggggacgga caatttgttc
    11101 cagaccggtt ttgattttag tgattccctg gatgacaacg gtgagttctc atatcgtctg
    11161 acggggctgg cgcgctcgac aaatgagcag caaaagagtt ctgagtcgca gcgctatgcg
    11221 attgcgccct cttttacctg gcgtcctgat gagaaaacga attttacgtt cctttcttat
    11281 ttccagaacg aaccagagac tggctactac ggctggctgc cgaaagaggg aacggttgaa
    11341 ccgttaccga atggtaaacg cttgccaaca gatttcaatg aaggggcgtc aaacaacacc
    11401 tattctcgta acgagaaaat ggtgggatac agtttcgagc atggcttcaa cgacactttt
    11461 accgtgcgcc agaatttacg ttttgtcgaa atgaaaaccg cgcaaaaaag cgtctatggc
    11521 acggggattg cggcggacgg ccatacgctt aaccgcggta ctatcgttga caacgagcgt
    11581 ttacagaatt tcagcgtaga tacacaactg gaaagtaaat tcgcgaccgg cgatattgat
    11641 catacgttgc tgacgggtgt cgatttcatg cgtatgcgta atgatattaa cgcgacgttt
    11701 ggtagcgcgc cgtcaatcga tctctataac aattaccatc ctgaatactt tgctttcggc
    11761 ggcgctgagc cgtaccagat gaacgaaagt aaacaaacag ccttatatgt tcaggatcag
    11821 gcggaatgga ataagtgggt atttactctc ggcggccgtt atgactggtc taaacaagcg
    11881 ataacggtgc gtcagaattc cactacgccg acagaaggat atattgaacg taatgaccac
    11941 cagttcacct ggcgcggtgg cgtaaactac gtattcgata atggaatttc accttacttc
    12001 agctatagcc aatctttcga gccaagcgcc ttcgatttgt ggagcacccc acgtgtttct
    12061 tacaagccgt caaaaggcga gcaatatgaa gcaggggtga aatatgtacc gaaagacatg
    12121 ccagttgttg ttacgggtgc cgtttatcag ctgaccaaaa ccaataacct gaccgccgat
    12181 ccaaccaacc cattagcgca ggtgccggca ggcgaaattc gtgcgcgagg tgtagagctg
    12241 gaagccaaag cagcattgac ggctaatatc aatatgacgg cgtcttacac ttatactgat
    12301 gctgaataca cgaaagacac taacctgaaa gggaatacgc cagagcaggt gcctgaacac
    12361 atggcgtcgt tgtggggcga ttacaccttc aacgatggtc cgttgtcagg tttaacgctg
    12421 ggaacaggcg gtcgttttat tggttccagt tacggcgatc cggccaatag cttcaaggta
    12481 ggcagcgcag cggtgatgga tgcggtcgtc aagtacgatc tggcgcgttt tggtatggcg
    12541 ggctccagca ttgcggttaa cgttaataat ctgctcgacc gcgaatacgt cgccagctgc
    12601 ttccagacct acggctgttt ctggggcgca gaacgtcagg tcgttgcaac ggcaaccttc
    12661 cgtttctaat ttctttttgg gcacggcttg ccgtgcccgt tttacaagtt ggctgcgatg
    12721 caggaaaacc acattcattc cgataccacc tttgcgctgc gaagcgtcgc ttttcgtgtg
    12781 ccgggccgca cgcttttaca ccccctctcg ttaacgtttc ccgcaggtcg agtcaccgga
    12841 cttatcggcc ataatggttc cggtaaatcc acgctgttaa aaatgctggg ccgccatcag
    12901 ctgccttccg aaggggatat tctgctcgac aatcagccgc tggcgagctg gagcagcaag
    12961 gcgtttgccc gcaaagttgc ctatctgcct caacaattgc cgcaggcgga aggaatgacg
    13021 gtgcgcgaac tggtggcgat tggccgctat ccgtggcacg gcgcgttggg acgctttggc
    13081 gtcgcggacc gggaaaaagt agacgaggcg attacgctgg tcggcttaaa accgctggcg
    13141 catcgtctgg tcgatagcct gtccggcggt gaacgccagc gcgcgtggat tgccatgctg
    13201 gtcgcgcagg acagccgttg tctgctgctg gatgagccga cgtcagcgct ggatatcgcc
    13261 catcaggttg acgtgctggc gctggtgcat cgtttaagcc aacagcgcgg gctgacggtg
    13321 gttgcggtgc tgcacgatat caacatggcg gcccgctact gtgattattt agtagcgcta
    13381 cgcggcggtg aaatgattgc gcaaggaacg cctgcggaac tgatgcgcag tgacacgctg
    13441 gaacagattt acggtatccc gatgggtatc cttccgcatc cggcgggcgc cgcgcctgtg
    13501 agttttgtgt attaatgcgt gagttatatc ctcttactcg ccgccgttta ttaacggcga
    13561 tggcgctctc gccgctgctg tggcaaatga atacggcgca ggctgccgct atcgatcccc
    13621 gccggattgt ggcgctggag tggctgccgg ttgagctgct gctggcgctc ggtattacgc
    13681 cttatggtgt ggcggacgtg ccaaattata agctgtgggt tagcgaaccg ccgttgccgg
    13741 attcggtgat tgatgtgggt cttcgcactg aacccaatct cgaactgctg acggagatga
    13801 agccgtcgtt tatggtgtgg tcggcaggtt acggaccctc gccggagaaa ctggcgcgga
    13861 tcgcgccggg gcgcgggttc gattttagcg acggcaaaaa gccgctggcg gtggcccgac
    13921 gctcgctggt tgaactggcg cagacgctga atctggaagc tgcggcagaa aaacatctgg
    13981 cgcaatacga tcgcttcatc gccagccaga agccacgttt tatccgccgc gggggacgtc
    14041 cgttactgat gacgacgctt atcgatccgc ggcatatgct ggtgctcggc ccgaattgcc
    14101 tgttccagga ggtgctggac gagtatggca tcgtcaatgc ctggcagggt gaaaccaact
    14161 tttggggcag tacggcggtc agcatcgatc ggctggcgat gtataaagaa gcggatgtga
    14221 tctgcttcga tcacgggaat agcaccgata tgaacgcgct gatggcaacg ccgctgtggc
    14281 aggccatgtc gtttgtccgc gccgggcgtt ttcaccgggt gcccgccgtt tggttctatg
    14341 gcgcgaccct ctccacgatg cattttgtcc gcatcctgaa taacgtgttg ggaggcaaag
    14401 cgtgagcaga aaacgtgaaa taccggatgg cggtgcgaaa aacgccttaa ccgacctacg
    14461 gttcgggcgc tttgtaggcc ggataaggcg aagccgccat ccggcgttgc tgttattggc
    14521 gctgttggtt gccgcctgct ggctgacatg ggttaacttc tccgttgcgc taccgcgcag
    14581 tcagtggcaa caggctatct ggtcaccaga tatcgacatc attgagcaga tgatttttca
    14641 ttacagccag ctgccaagac tggcgatttc gctgctggtg ggcgcggggc ttgggctggt
    14701 aggcgtcctg ttccagcaag tattacgtaa cccgctggcg gaaccgacca cgctgggcgt
    14761 ggcgaccggc gcgcaattgg ggatcacggt gactacgctt tgggcgattc ccggcgcgct
    14821 gaccacgcag tttgccgccc tgacgggagc ctgcatcgtc ggcgcgctgg tgttcggcgt
    14881 ggcgtggggc aaacgtctgt cgccagtgac cctgatcctc gccgggctgg tggtcagcct
    14941 ctattgtggc gcaatcaacc agttactggt gattttccac cacgatcagt tgcaaagcat
    15001 gtttttatgg agcactggaa cgctaacgca aaccgactgg agcggcgtgc agcgtctgtg
    15061 gccgcagttg ctgggcggcg tgatgctcac gttattgttg ttacgtccga tgacgctgat
    15121 ggggctggat gacggcgttg cgcgtaatct ggggctggcg ctgtcgttag cgcgtctggc
    15181 ggcgttgtcg ctggcgattg tgttgagcgc gctgctggtc aacgcggtgg gcattatcgg
    15241 ttttatcggc ctgtttgcgc cgctgctggc gaaaatgctt ggcgcaagac gtctgctggc
    15301 gcgcctgatg ctggcgccgc tcattggggc gcttatttta tggctatccg atcagattat
    15361 cctttggcta acccgcgtat ggatggaagt ctccaccggg tcagtgacgg cgttaatcgg
    15421 cgcgccgctg ctcctatggc tgctgccgcg gcttaaaagc atgagcgcgc cggatatgaa
    15481 cgccagcgat cgtgtggcgg cggagcgtcg acatgtcctc acttttgccg ttgccggtgg
    15541 cgcgctcctg ctgctggcaa catgggtcgc gctctctttt ggtcgcgacg cgcacggctg
    15601 gacgtgggcg agcggaacgc tgcttgaaga actgatgccg tggcgctggc cgcggatact
    15661 ggcggcgtta atggcgggcg tcatgctggc ggtggcgggc tgcattattc agcgtctgac
    15721 cggtaaccca atggccagcc cggaagtgct ggggatcagt tccggagccg cgtttggcgt
    15781 ggtgttgatg ctgtttttgg tgccggggaa tgctttcggt tggctactgc ctgccggaag
    15841 cctgggcgcg gcggcgacac tgctgattat tatgatagcc gccgggcgcg gcggtttctc
    15901 gccgcaacgg atgttgctgg cggggatggc gctcagcacc gcgtttacca tgctgctaat
    15961 gatgctccag gcgagcggcg atccgcggat ggcggatgtg ttgacctgga tctcaggatc
    16021 tacctataac gccactggcg ggcaggttac gcgaaccgcg atcgtgatgg tgattttgct
    16081 ggccgttgtg ccgttgtgtc gccgctggtt aacgattttg ccactgggcg gcgatgccgc
    16141 gcgcgcggtg ggcatagcgc ttacgccgtc gcgtatcgcg ctgctggcgt tggcggcttg
    16201 tttgacggca accgcgacga tgaccattgg gccgctgagt ttcgttggat tgatggcgcc
    16261 gcatattgcg cggatgctcg gttttcgccg gacgatgccg catatggtca tctcagcgct
    16321 ggcagggggc gttttattgg tctttgccga ctggtgcggc aggatggcgc tatttccgta
    16381 tcagatcccg gcgggactgc tttcaagctt tattggcgcg ccgtacttta tctatttgct
    16441 acgtaaacag agccgctgag tttgccggat ggcggcataa atgccttatc cggcctgcgg
    16501 tgtagaatgt aggccgggta agcgtaagcg tcacccggca attcatcctt tacaatttcg
    16561 caaacacccg acgcgcggcg tcaatagtat tattaatgtc gtccatgctg tgtgcgaccg
    16621 acataaaacc cgcctcaaac gccgatggcg ccagatacac gccttcctcc agcatcaggt
    16681 ggaagaaacg cttaaagcgt tccacgtcgc acgccatcac gtcctgatag caagttacgc
    16741 tctcagcgtc ggtgaagaaa atcccgaaca tgccgccgac atggttaacc accagcggaa
    16801 tattcgcttc ttcggcagct tccagcaaac cttccgccag gcgggtggtg agctcatcca
    16861 gcgtttcatg aatgccgggc tgggcgactt cattcaggca ggcgaaaccg gccgccatcg
    16921 caatcgggtt gccggaaagg gtgcccgcct ggtaaaccgg gcccgtcggc gccagcgcat
    16981 ccattacatc gcgacgaccg ccaaacgcgc ctaccggcat cccgccgccg atgattttac
    17041 ccagacaggt caggtccggc acgacgccgt agtaatcctg ggctccggcc agcgctacgc
    17101 gaaaaccggt cattacttcg tcgataatca gcagcgcgcc gaactcatcg cacaaggcac
    17161 gcaggcccgg caggaattcc ggcagcggcg ggacgcagtt catattgccc gccacgggtt
    17221 cgacgatgat acaggcgatt tcctgcggat attgttcaaa cgccgcgcgc actgacgtca
    17281 gatcgttata agtgcaggtc agcgtatgtt tcgcgaaatc tgccggcacg cccggcgagt
    17341 tcggctgacc gagcgtcagc gcgccagaac cggctttgac cagcagacag tctgcgtggc
    17401 cgtggtagca gccttcgaat ttgataatct tatcgcggcc agtaaaacca cgcgccaggc
    17461 gaatcgcgct catcgtcgct tcggtgccgg agttcaccat gcgcaccatg tccatggtcg
    17521 gcaccaggtt ggtcaccagt tccgccattt ttacttccat ttcggttggc gcgccgaagc
    17581 ttaaaccgcg ctccgcagct tcgatcaccg cattgcggat agccggatgg ttatgcccca
    17641 gtaccattgg cccccaggaa ccgacatagt cgatatatgc tttgccatcg acatcgtaca
    17701 gatacgcgcc gtccgctttt tcgataaaca gcggggtgcc gcccacgcca gtgaaggcgc
    17761 gaacagggga gttcacgccg ccggggatca gctcgcgggc cgcgctatag agattttcag
    17821 acttactcat ggaaagattc ctggttcgta gaaaaagtga atacccgcta ttctaagtta
    17881 ttcagagaag gttatgaaag ttttacgcat ttgaaacaat acgatttgca ggggattttc
    17941 acggcgttgg cgagtagaat gccgacttta gatttgtatt accaattaat gatcttctga
    18001 tgaaaacaga cacttccacc tttttagctc agcaaattgt gcgcttacgg cgcagagatc
    18061 agattcgtcg gttaatgcag cgggataaaa cgccgctggc catcctgttc atggcggccg
    18121 ttgtcggcac gcttaccgga ctggttggcg tcgcctttga aaagacggtt tcctgggtac
    18181 aaaacatgcg cattggcgcg ctggttcagg tcgcggacca tgcgtttttg ctttggccgc
    18241 tggcctttat cctttcggcg ttactggcga tggtcggcta ttttttggtg cgaaaatttg
    18301 cgccggaagc cggcggctcg ggtatcccgg aaattgaagg cgcgctggag gagttacgtc
    18361 cggtgcgctg gtggcgcgtg ttgccggtga agtttatcgg cgggatggga acgttgggcg
    18421 caggaatggt attagggcgc gaagggccaa cggtgcaaat cgggggcaac ctggggcgca
    18481 tggtgctgga tgtttttcgt atgcgcagcg ccgaagcgcg gcatacgttg ctggcgaccg
    18541 gcgcggcggc ggggctctct gcggcgttta acgcgccgct ggcgggtatc ctgtttatta
    18601 ttgaagagat gcgcccgcag tttcgctaca acctgatttc gattaaagcg gtgtttaccg
    18661 gcgtcatcat gtcgagcatt gtgttccgca tatttaacgg cgaagcgccg attattgaag
    18721 tcggcaaact gtctgatgcg ccggttaaca cgctgtggtt ataccttatc ctcggtatta
    18781 tttttggctg cgtcgggccg gtatttaatt cgttggtgct gcgtacccag gatatgtttc
    18841 agcgctttca tggcggcgaa attaaaaaat gggtgcttat gggcggcgcg atcggcggcc
    18901 tgtgcggtat tctggggttg attgagccgg cagcggcagg cggcggattt aaccttattc
    18961 ctatcgccgc ggcaggtaat tttagcgtcg ggctactgct gttcatcttt attacccggg
    19021 ttgtcacgac gctgctttgc ttttcttccg gcgcgccggg gggcattttc gccccgatgc
    19081 tggccctggg aacgctgctt ggtacggcct tcggtatggc ggcggcagtg cttttcccgc
    19141 agtatcacct ggaggccggt acctttgcga ttgccgggat gggggcgctg atggcggcgt
    19201 cggtgcgcgc cccgttgacg gggattgtgc tggtgctgga gatgaccgat aactatcagc
    19261 tcattttgcc aatgattatc acctgtcttg gcgcgacact attagcccag tttttgggcg
    19321 ggaaaccgtt atactcaacc atcctggcgc gcactctggc gaagcaggat gcggaacagg
    19381 cggcgaaaaa ccagaatgcg cctgcgggcg agaatacttg aacgaattac cagggtatta
    19441 gataatgact gccaatattg ggtgaaaatt tatccaatta ccgatgtcgt ttggagcaaa
    19501 atatgagtga tgacgtagcg ctgccgctgc agtttaccga cgcagcagcg aataaagtaa
    19561 aaagtcttat cgctgacgaa gataacccga atctgaaact gcgcgtgtat atcaccggcg
    19621 gtggttgcag cggcttccag tatggtttta cctttgacga tcaggttaac gaaggggata
    19681 tgaccatcga aaaacagggc gttggcctgg tggttgaccc gatgagtttg cagtatctgg
    19741 tgggtggttc ggtagattat accgaaggtc tggaaggttc ccgcttcatt gtaaccaacc
    19801 cgaatgcgaa aagtacctgc gggtgtggct cttccttcag catttgattg ctgttcgttg
    19861 tgccggatgg cgacgcgagc gtcttatccg gcctacagga aagatgttcc aggcccgata
    19921 agcgtagcgc catcgggcaa aacaatatca acgtccgttt tcatccaggg caaacgtcgg
    19981 caatttcaaa tgccagcgaa tggccgccag ccgaataaac agcgtgacga ccatgcccat
    20041 catgctagcg ctttccagcg gtactgaaaa cgtataaaac gcggtggcgt gaacaatccc
    20101 gccgataata caggccgtgg catagatttc ggtgcgtagg atcatgggga tctcgcgtgc
    20161 cagaacatcg cgaataatcc cgccgccgac gccggtaatc acgcccatac agacggccac
    20221 taatggcccc gtttcagcga ggaaggcttt attcacccca atgccgacaa acaccgccag
    20281 cccgaccgca tccagtaccg gcaacatcca tttcggcaga cgtctcggct ggcgaaccag
    20341 caggatggtc agcatactgg tgaccatggc gacgaccagg tcggtaggat ctttaaccca
    20401 gaataccggg ccgttatcca gcgccatatc gcggattgtc ccgccgccga cggcagtaac
    20461 gacgccgagc accaggacgc cgaacgggtc catacgtaat ttcccggcca gcaacacgcc
    20521 agagatagca aatacagccg tgcctacaat atccagccaa tagacgagca ttgtcgaatc
    20581 cccactagga gcctggtaag acaggctcta attcacctgt gaaagcgcat tacagagttg
    20641 ttttgcggcg aggataatac gcgggcttgc gcgttcaaac cagtcgctgt taagcggaat
    20701 aaccggaatt tttaacaggt ttccccagta ttgttcaatt ttgagaattt cgcccgcttt
    20761 tccggccacg ataatggcct ggggatgcct tgccagcacc tgctcacggc tgacttgcgg
    20821 ccacggcacg cggctgtcag caaagacgtt ttctccgccg caggtcgtca aaacctgatg
    20881 ttgaatagac cctttaccac tggtaaacag aggattcatg ccaaactgaa gaaagacgcg
    20941 ctttttagct ttaccggcat actcgacttt gagcgcggcg tactctttta gcaatgtctg
    21001 cgctgcctgc tgagcctttt ccggctgcgg gctccaggcg gccagttggc ggagcgcgtc
    21061 ggcgatctgt tcgatggtta ccgcgtccac ccacatgacc ttaataccta atgacgtcag
    21121 ttggtttacc tggcgttccg cattaccgcc gcgccaggcg acgaccagat ccggcttcag
    21181 cgccacaatg cgctccagat tcattccctg ccaggtagag acctgttcta ttttttgcgc
    21241 ttcgggcggg tagtcggaat agctgctgac gccaacgggc gtaatctcgg cggcaaaagc
    21301 aagctccgta ttggcgggag agagcgtaat tacgcgcggc gcagcgtaaa gccacaccgg
    21361 gagcgtaagc agcagggcgc ccagcgccct gaacatttgc ttagccatgc gccagtttct
    21421 gtaccagcgt ttcgaccatc agagtcgact gtttcgccgc caccgcgagg aattcgtcaa
    21481 agctgaggtg cgattgctga tcggccacgt cagagatagc gcgtaccacc acgaacggca
    21541 cgttgaagtt atggcagacg tgggcgatag cggtggcttc catctctacg gcgaccgcgt
    21601 cggggaagtt atgccggatt ttcgccagcc cgacggaacc gttaataaac gcgtcgccgc
    21661 taacaataag gccgcgtacc gcgttcagat tcaactccct gatgcaggat tccgcggcgg
    21721 cgatcagctt atcatcggcc ttaaatccgg ccggacagcc cggtaattgc ccgtattcat
    21781 agccgaaagc ggtcacatca gcgtcgtggt aacgcgcttc gtcagagacg acgatatcgc
    21841 cgaccttcag cgtggacgcc agaccgcctg cggaaccggt attgatgatc acgtccggct
    21901 tgcagtgctc cagaagcaac gttgcgccca gcgccgccgc gactttaccg ataccggatt
    21961 tcagcaacgc cacttcggtg ccgttcaact ggccagtgta aatttcgcag ccgcccagcg
    22021 taatcgtctg acggttgtca attttgtcac gcagcagcgt aacttcttct tccattgcgc
    22081 caatgatgcc gattttcata gatttactcg cgataagtca gttttggggg catagtttat
    22141 catgcgctta tggggaagcg catttctcag gcggggagag gatatggcat cgatcgattt
    22201 ccgaaataaa attaactggc atcgtcgtta tcgttcaccg cagggcgtaa agacggaaca
    22261 tgagatcctg cggatttttg aaagcgatcg cgggcggatt atcaactctc cggctatacg
    22321 ccgtttgcag caaaaaacgc aggttttccc gctggagcgc aatgccgcgg tgcgtactcg
    22381 tctgacgcat tcgatggagg tgcagcaggt ggggcgttat atcgcgaaag agattttaag
    22441 ccgcctgaaa gagcaaaacc gactggagga gtacggtctg gatgcgctga ccggtccctt
    22501 tgaaagtatt gtggaaatgg cctgtctgat gcacgacatc ggtaatccgc cgttcggtca
    22561 ttttggcgag gcggcgatca atgactggtt tcgtcagcgg ctgcatccgg aagatgcgga
    22621 aagccagccg ctcacgcatg atcgctgtgt ggtttcctcg ctacggttac aggaaggtga
    22681 agaaaatctg aacgatattc gccgcaaagt acgtcaggat atctgccatt ttgaaggtaa
    22741 tgcacaggga attcgtctgg tacatacgct catgcggatg aatcttacct gggcgcaggt
    22801 tggcggaatt ttaaaatata cccgtccggc atggtggcga gggccggtgc cggattccca
    22861 tcgctattta atgaagaaac cgggctatta tctttctgaa gagaagtata ttgcgaggtt
    22921 acgtaaagaa cttcagttag cgccttacag tcgctttcca ttaacgtgga ttatggaagc
    22981 cgcagatgat atttcttatt gtgtcgccga tcttgaagac gcggtagaga aaagaatctt
    23041 tagcgttgag cagctttatc accatttata tcacgcgtgg ggccaccatg agaaggattc
    23101 gctgtttgag ctggtggtag gaaatgcgtg ggaaaaatca cgcgccaata cattaagccg
    23161 cagtaccgaa gatcagtttt ttatgtattt acgggtaaat acattaaata aactggtgcc
    23221 ctatgccgct cagcgtttta ttgataattt gccgcagatt tttgccggta ccttcaatca
    23281 ggcgttactg gaagatgcca gcggttttag ccgcctgctt gaactctata agaatgtggc
    23341 ggttgaacat gtgtttagcc atccggatgt agaacagctt gaactacagg gataccgggt
    23401 gatcagcggg ttattagata tctatcagcc gctattaagc ttgtcgctta acgactttcg
    23461 cgagctggtg gaaaaagaac ggttgaaacg cttccctata gaatcgcgct tatttcagaa
    23521 actttctacg cgccatcgtt tggcctacgt ggaagtcgtc agtaaattac ccacggattc
    23581 ggcggagtac ccggtactgg aatattatta tcgctgtcgg ttgattcagg attatatcag
    23641 cgggatgact gacctttacg catgggatga atatcggcgt ttgatggcgg tcgaacagta
    23701 aatggacttt tgtaaagatg gacaataaat ttttactttt tccagaaact ttattccgga
    23761 acttcgcgtt ataaaatgaa tctgacgtac acagcaattt tgcgttacct gttaatcgag
    23821 attgaaacac atgaaaaaaa ccacattagc aatgagtgca ctggctctga gtttaggttt
    23881 ggcattgtcg cctctgtctg ccacggcggc tgaaacgtcc tcttcagcaa tgactgccca
    23941 gcagatgcca agcctggcac cgatgctcga aaaagtgatg ccatcggtgg tcagtattaa
    24001 tgtagaaggt agcaccacgg tgaatacgcc gcgtatgccg cgtaatttcc agcaattctt
    24061 tggcgatgac tccccgttct gccaggacgg ttctccgttc cagaattctc cgttctgcca
    24121 gggcggcggt aacggcggca acggcggtca acaacagaaa ttcatggcgc tgggctccgg
    24181 cgtaattatt gacgccgcga agggctacgt cgtcaccaac aaccacgtgg ttgataacgc
    24241 cagcgtgatt aaagtacagc ttagcgatgg gcgtaaattc gatgctaaag tggtgggcaa
    24301 agatccgcgt tctgatatcg cgctgattca aattcagaat ccgaagaacc tgacagcgat
    24361 taagctggcg gactccgacg cgctgcgcgt gggggattat accgtcgcta ttggtaaccc
    24421 gtttggtctg ggcgaaacgg tgacgtcagg tatcgtttcg gcgctggggc gtagcggcct
    24481 gaacgtagaa aattacgaga actttattca gaccgacgcc gcgattaacc gcggtaactc
    24541 cggcggcgcg ctggtgaacc tgaacggtga gctgatcggt attaacaccg cgattctggc
    24601 gccggacggc ggcaacatcg gtatcggctt cgctatcccc agtaacatgg tgaaaaacct
    24661 gacgtcgcag atggtggaat acggccaggt gaaacgcggc gaactgggga tcatggggac
    24721 tgagctgagc tctgagctgg cgaaagcgat gaaagtcgac gcccagcgtg gcgcgttcgt
    24781 cagccaggtg atgccgaatt cgtccgcagc gaaagcgggt atcaaagccg gggatgtcat
    24841 tacctcgctg aacggtaaac cgatcagcag ctttgcggcg ctgcgcgctc aggtcggcac
    24901 tatgccggtc ggcagcaaaa tcagcctcgg tctgctgcgt gaaggtaaag cgattacggt
    24961 taatctggaa ctgcagcaga gcagccagag tcaggttgat tccagcacca tcttcagcgg
    25021 gattgagggc gctgaaatga gtaataaagg ccaggataaa ggcgttgtgg tgagcagcgt
    25081 gaaagcgaac tcacccgccg cgcaaattgg cctcaaaaaa ggcgatgtga ttatcggcgc
    25141 taaccagcag ccggtgaaaa atatcgccga gctgcgtaag attctcgaca gcaagccgtc
    25201 ggtgctggcg ctgaatattc agcgtggtga tagttctatt tatttgctga tgcagtaatc
    25261 acctttgtcc cccttccacc acggaagggg gcaacacttt tctgtgaaac tccccacaac
    25321 tccatacttc tttgcaccgt tttgtgcatt tgcacaatgt cgaggcctgt catcttcctt
    25381 atgcttgtgc tctgctcaca ggagggattt atggctggct ggcatcttga taccaaaatg
    25441 gcgcaggata tcgtggcgcg cactatgcgc atcatcgata ccaatatcaa cgtaatggat
    25501 gcccgcgggc gtattatcgg cagcggcgat cgggaacgta ttggtgaatt gcacgaaggc
    25561 gcgttgttag tgctgtcaca gggccgggtt gtggatatcg acaacgccgt ggcgcgacac
    25621 ctgcacgggg tgcgtcaggg gattaatctt cccttacgcc ttgagggcga aattgttggc
    25681 gtgatcggtc tcaccggcga accagagcat ctgcgtaaat atggcgaact ggtgtgtatg
    25741 actgccgaaa tgatgctgga acagtcgcgg ttaatgcacc ttttggcgca ggatagccgt
    25801 ttgcgtgaag agctggtgat gaacctgatt caggccgaag aaaatacgcc ggcgctggtg
    25861 gaatgggcac agcgtttagg gatcgatttg aaccagccgc gtgtggcggc ggtggtggaa
    25921 gtcgacagcg gccagcttgg cgtcgatagc gcaatggcgg aacttcagca gttgcagaat
    25981 gcgcttacca cgccggagcg taacaacctg atagccattg tttcccttac cgagatggtg
    26041 gtgctcaaac ccgccttaaa ctcgtttggt cgttgggatg ctgaagatca tcgtaagcgc
    26101 gtagagcagc ttatctcgcg aatgaaagag aatggtcagc tacgttttcg cgtggcgctg
    26161 ggtaattact ttaccggacc gggcagtatt gcacgctcat accgcacggc gcgcaccacg
    26221 atgatggtcg gcaaacagcg gatgccagaa agccgcagct atttttatca ggatttgatg
    26281 ctgccggtcc tgttagatag cctgcgtggc ggctggcagg ccaatgagct ggcgcgcccg
    26341 ctggtaaaac tcaaagcgat ggataacaac gggttattac gtcggacact gacggcgtgg
    26401 tttcgccata atgtccagcc gctggcgacc tctaaggcgc tgtttattca tcgtaatacg
    26461 ctggaatatc ggctaaatcg tatttcggaa ctgaccgggc tggatttggg aaattttgac
    26521 gatcggctgt tgctgtatgt ggcgctacaa ttggatgaac agcgttaagc ccggcggcgc
    26581 ttcgcttacc aggcctacgg ggatatacct gtaggccgga taaggcgtaa cacgtcgcca
    26641 tccggcaaca cacagcttac ttacgggtaa gcttgtccag atcggcttcg atttcactga
    26701 tcttattcgc gacgacgctt tccagatggc gcaagtcgtc gaggatctta cgtttgagat
    26761 cgagttctga gcggtcgcgc tggcagattt ggtccagctc gtcaatcaca tagcgtaggt
    26821 tagggctaat ctcctgtact tctttataac cctgaccgat gccatcagcc accaccgttt
    26881 tacgctggcg tggatactta aacttcacgc ttttagcaaa gaattcacct ctatcctttt
    26941 gaaaatagat tttcaggata tcgttattgg cttcttgccg caggctgtaa cgatcgattt
    27001 cctcaggatt ggtaatgccc agacttttta gattgtcata catagcggta tccttcatca
    27061 cactataact tttgaataat taacgaaaaa ttggtttttc gccaccaatg gatacaaaaa
    27121 aagcgcggtt gatcgcagaa gacgtctcgg caacgtcatg agcaaaaggg cggcggttat
    27181 tgatagctta agtaattcaa cgcgatattc cgtttataga gaaagcgttt gaggtcagtg
    27241 tgggaaattg accggaggca gtggtcgata accttgagag gcggaatcta tgtccggaac
    27301 gtataatgcc actattcgcc gggtggtgat ttccgcctgg ataggaaact ccattgaata
    27361 ttatgatttt ctattatacg gcttagcaag cgcgctggta tttggcccgc tttttttccc
    27421 ctggcgccag cccattgact gcaacgttat cttcttttgc cagtttcggc gtgggattta
    27481 tttcccgacc gctgggcgcg ctattttttg gcaacagggg ggatacgctt gggcgtaaaa
    27541 acacgttatt aatcacgtta ggcgggatgg gcgcggtcac gtttctcatc ggttgcctgc
    27601 cttcttacgc cagtatcggc gcgctgacac ctgctttact ggttattcta cgttttctac
    27661 agggatttat ggttggaggt gaatggggag gcgccatgtt gatggtcgtg gaatatgctg
    27721 ctggaaagca ccgggggcgg ttaagcgcgc tatcgcaaac aggaggactc acgggacaat
    27781 tattggcgac aggcgtattt atagtcgtga cccaattacc gcaggaggcg ttgttatcgt
    27841 ggggatggcg tattcctttt ctgctcagtg cgcttttggt gttgccggga ttatatatgc
    27901 gtcatcgtct ggatgagacg cctgtcttcc gtgcgtttaa aaagcagcag gccattaatc
    27961 ataggcagca aagggatgaa aggccggtgg tcaaagtagt acgagaacaa tggcgtagca
    28021 ttttgctgat tataattctg cgttttgcgg aaagcgttcc cttttttctt gctaccgtct
    28081 tcgcggtttc ctgggcgacg acgcagcttg ggattgccag cctgactatt ctgtacattg
    28141 taatgttcac ctgtctgctg gcgtatccca tgcacgtgct atttggcatc atgtcggatc
    28201 ggcgtggctg ccgtcaggtg tatattttcg gcgcgctttt tgtcgcggca atggcttttc
    28261 cctttttctg gctgctggaa agccgttcgc tcatactgat gacaatgggc tacgttctgc
    28321 ttattaacat tggtcataat tcactgaatg ccgtgcaacc ttcttttttc gccggactgt
    28381 ttcatccgcc tgtacgctac agcggttcat caattggcgc tcagttgggg gcggttgtgg
    28441 cagggggatt cacgccgttt atcgctaaag cgttaagcgc agtctatgat aacagttgga
    28501 ctttggttgc cggttatgtc gttttgactg cgctggcttc ggcgtttgcg gcaaagattg
    28561 cgccggacac cgtgttaccg cattcgccgt aatgcaaagg ggggctgtcg cccccgcttt
    28621 tcactcgctt aatcaatcgt gcgcaataat tcgttaatgc ccactttacc acgcgttttg
    28681 gcgtcgactt ttttcacgat caccgcgcag tacaaactgt acttaccgtc ttttgacggc
    28741 aggttgccgg aaacgaccac ggagcccgcc ggtacgcggc catagtgaac ttcaccggtt
    28801 tcgcgatcgt agattttggt gctctggccg aggtatacgc ccatggaaat gacggaacct
    28861 tcttcgacaa tgacgccttc cacgacttca gaacgcgcgc caataaagca gttgtcttca
    28921 atgatggtcg ggttagcctg cagcggctcc agtacgccgc cgatacccac gccgccggaa
    28981 aggtgaacat ttttaccaat ctgcgcacag gaacccaccg tcgcccaggt gtcaaccatg
    29041 gtgccttcgt caacgtaggc gccgatgtta acgtaagacg gcatcagcac ggtgttgcgg
    29101 gcgataaatg cgccctgacg aacggccgca ggcggaacga cgcggaagcc ttctttctga
    29161 aaacgcgctt cgtcgtaatc agcgaatttc atcggggctt tatcgaagta gcggctttcc
    29221 gcaccgtcga taacctggtt atcgttaata cggaaagaga gcagaaccgc tttcttcaac
    29281 cactggtgag tgacccactg accgtcgatt ttttctgcga cacgcagcgc gccggaatca
    29341 agtagagaaa tgacctgttt taccgcctct cgggtcacgg tatctacatt agccggcgta
    29401 atatcggcgc ggcgctcaaa agcggtctca ataacgttct gtaactgctg cattgttaaa
    29461 ctctttcata taaataaaca cactaccctt tatcgtttgg attgagggcc gctgtcaacc
    29521 gttgttgcac ctcaagttgc agcacattat taagtgcgcg ccgatccgct gtggcgatta
    29581 tgaataaatc ttctactcgt tcaccaatgg ttgtaattcg ggcaccatga agcgaaattc
    29641 ccagatcggc aaaaatttgt ccgaccctgg ccagcagacc aggttgatcg agcgcgatca
    29701 attccatgaa tgattttctg tcggtatggg tgggcagaaa attgacttcc gtttcgaccg
    29761 taaagtgccg taactttgcc ggttgccgac gcggctgcgg cggctgccag ctatgctgcg
    29821 taatggtctg ttcaagaccg gtgcgaataa cgtcatggcg atctgccgcc agcgggctgc
    29881 cgtctggttc cagaacgata aacgtatcca ttgccatgcc gtcgcgagtg gtaaagatct
    29941 gcgcgtcatg gacgcttaaa ttacgcctgt ccagctcggc gcagacggcg gcaaacagat
    30001 agggtctgtc cggactccag ataaaaattt cggttccgcc gcgcgtggct tgcggactga
    30061 gcaacactaa cggttggctc agatcgtgct gcaataaatg gcgtgcgtgc caggcgagct
    30121 gatttggact atgacgaaca aaatagttag cgcgacagcg ggtccagatt ttgtgcagcg
    30181 cggcttcatc aatattgtcc attcgcagca gcgccagcgc ctgaagctga tggtgacgca
    30241 cgcgctcacg catatccggc gtattttgca ttccacgcct gagctgtttt tcagtggcga
    30301 agtacagctc gcgcagcagg ctctgtttcc agctattcca caaggtttcg ttggtcgcgc
    30361 agatgtccgc gacggtcagg cagaccagaa aacgcagccg tgtttcggtt tgcacctctt
    30421 cggcaaactg cttgatgact tccggatcct ggatgtcgcg gcgctgagcg gtgactgaca
    30481 ttagcaggtg ttggcgcacc agccaggcga ccagttgcgt ttcgcgtgag ttcaaaccgt
    30541 gcagttcggc gaaggtgagt acatcctgcg cgcccagtac cgaatggtcg ccgccgcgtc
    30601 ctttcgcaat atcgtggaac agcgcggcga tcaggatcag ttccggatgg ggaagccgcg
    30661 gccagagatc gacgcatagc ggatggcgct ggcgtgtctc ttctttcgca aagctctcca
    30721 gtttgagcat tacgcggatg gtgtgttcat ccaccgtgta tgcgtggaac aggtcaaact
    30781 gcatttgtcc gacgatgtgc gaccactgcg gcatataagc ccacagtacg ctgtggcgat
    30841 gcatgggcag caggccgcgg ctgaccgcgc cgggatggcg tagcatactc agaaacagag
    30901 tgcgcgcctc cgggatgtaa cacagcggtt ggctcaggtg gcggcgggcg tggcgcaagt
    30961 ggcgtaacgt cgtagagtag atgccggtga tcgcgctatt gcgcaccatc atataaaaca
    31021 tccgcaggat cgcttgcggt tcgcggataa acagcgtgtc gtcacgcaga tcaatgagcg
    31081 tgccgcgcag ttgaaactca tcgtcaacag gacgtggttt ttcatccgca ggcagcgcca
    31141 gaatcgcctc gtcaaatagc tgaagcagca tctgattaag ttcgctcacc cgacgcgtaa
    31201 cccggaagta gtctttcatc atccgctcaa ccggatcatt gccctcgccg ctgtagttaa
    31261 ggcgttgagc gacgcttaac tggcggtcga acagcaggcg gttatcgtag cggctgacca
    31321 ccagatgtag cgcaaagcga atgcgccaca ggatatgcag gcactcgttg agctccgcgc
    31381 actcagccgg ggttaaaaag ccgaatccca ccatctcatc gagcgaggtg gcgccgaagt
    31441 gacgtcgggc gacccactgc aatgtatgga tatcgcgcag gccgccgggg ctgcttttaa
    31501 tatccggctc cagattatag ctggtaccgt gatagcgctg gtggcgctgg ttctgctctt
    31561 ctactttggc ggcgtaaaat ttgtcggacg gccaaaaacc ttcgctgaaa atatgttttt
    31621 gtagtgccag aaacagagcg acatcaccga tcagcaggcg cgtttcgatg aggtttgttg
    31681 caacggttaa atcagacaga ccttccagca gacactcttc cagcgtacgt acgctatgcc
    31741 cgacatccag cttgacgtcc caaagtaaag tcagcagctc gccgaccttt tgcgcctgtt
    31801 catcgggcag ctttttgcgg cttaaaatga gcagatcaat atcggaaagc ggatgcagtt
    31861 cgccgcgtcc atagccgccg acggcgacca gcgccagatc ggcaatctga ccgaaaccgg
    31921 cctcaatcca caggcgttgc aacaactggt cgataaattc ggttcgggct tcaataagct
    31981 gttcagcaca aatgccgctg tcaaatgcct ctcccagcca gtgttgaaag atgtcgatgc
    32041 gggctttgat accggcgacg gtcagttcag cgcgcggcca gacgccaggg ttttgcggct
    32101 ggtcagggag ggtggggagt gcggtattcg cgtgctgttc aggaagagta ttcatatgcg
    32161 ccacccatta aaaagccgga tggtggcgtg aacgccttat ccggcctacg aagtagtaca
    32221 atttgtaggc ctgataagat gcgaaggcat cgccatcagg caaaacatta ttcgtcgtgt
    32281 gtgatgatcg ccgggatggt gtcatcttta cgcagcgtca gaatttcaca gccgttttcc
    32341 gttaccacaa tagtatgctc gtactgagca gacaagctgc ggtctttggt ttttaccgtc
    32401 cagccgtctt tcatggtgcg gatacggtaa tccccggcat tcagcatcgg ttcaatggta
    32461 aaggtcatgc caggctgcaa cacgacgcca ccatcgtctg catcataatg cagcacctgc
    32521 ggttcttcat ggaagccgcg accaataccg tgtccgcagt attcacgtac cacggagaaa
    32581 ccttcgcctt cggcatattt ctggatggcg gcgccaatgg tgcgcaggcg gatgcccggt
    32641 ttcaccattt tgatgcccag atacaggctc tcttgcgtga cgcggcacag acgctcgccc
    32701 agaatagtcg gtttgccgac gataaacatc tttgaggtat cgccgtggaa ttcatcttta
    32761 atcacggtca cgtcgatgtt gacgatatca ccatctttca gatgtttagc gtcatccgga
    32821 atgccgtggc acaccacttc attaatagag atacagacgg atttcggata gccgtggtag
    32881 ccgaggcagg cggagatcgc gtgttgttcg ttaacgatgt aatcgttaca gatacggtcc
    32941 agttcgccgg tggtgacgcc cggtttgata tacggttcga tcatttccag cacttcggct
    33001 gccagacggc ccgcgacgcg cattttttcg atgtcttcag atgtcttgat agagatagcc
    33061 atgaattctg tccatcagtg ccgatgattt cggcaataat tgtgtaagtg ctgacaatgg
    33121 tatcagtcag gggtgtaccc tgccaaattg agaatcattc tgaacttcgc ctttcgtgcc
    33181 acaggtgcgt tggcgacatt ttttcacccc agtcacttac tggccgtaag ctcccgggga
    33241 tgcaaaaatt tgccgcctgc ctgtaacacg aaattcatcg ttcaattcag cactgagtgc
    33301 caacaattat tggtgtcggt ggcgtatttg tggtataaag cgtgccggac ttccgatcca
    33361 ttcgaagact acacacgatg gacgggagcg acaaatctca ctttgtgtaa caacacacac
    33421 gtatcggcac atattccggg gtgccctttg gggtcggtaa tatgggatac gtggaggcat
    33481 aaccccaact tatctataga ggttttaaat catggcaact gtttccatgc gcgacatgct
    33541 caaggctggt gttcactttg gtcaccagac ccgttactgg aacccgaaaa tgaagccttt
    33601 catcttcggc gcgcgtaaca aagttcacat catcaacctt gagaaaactg taccgatgtt
    33661 caacgaagct ctggctgaac tgaacaagat ctctgctcgt aaaggtaaaa tccttttcgt
    33721 tggtactaaa cgcgctgcaa gcgaagcggt gaaagaagct gctaacagct gcgaccagtt
    33781 cttcgtgaac catcgctggc tgggcggtat gctgactaac tggaaaacag ttcgtcagtc
    33841 catcaaacgt ctgaaagacc tggaaactca gtctcaggac ggtactttcg aaaagctgac
    33901 caagaaagaa gcgctgatgc gtactcgtga gcttgagaaa ctggaaaaca gcctgggcgg
    33961 tatcaaagac atgggcggtc tgccggacgc tctgttcgtt atcgatgctg accacgagca
    34021 cattgctatc aaagaagcga acaacctggg tatcccggta tttgctatcg ttgataccaa
    34081 ctctgatccg gacggcgttg acttcgttat cccgggtaac gatgacgcaa tccgtgctgt
    34141 tagcctgtac ctgggcgctg tcgctgcaac cgttcgtgaa ggccgttctc aggatctggc
    34201 ttcccaggcg gaagaaagct tcgtagaagc cgagtaataa ggcttgataa ctccctaaaa
    34261 tagttcgagt tgcaggaagg cggcaagctc gagaattccc gggcgcttac atcagtaagt
    34321 gtccgggatg agcgagtgaa ggcaacgcgc ctgcggctcg aaatatgaag gggagagccc
    34381 ttatagacca ggtagtatca cgtttggtta gggggcctgt atatggcccc ctttttcact
    34441 tttatatctg tgcggtttga tgccgggcag atcaaatctt tcgaggattt tagaatggct
    34501 gaaattaccg catccctggt aaaagagctg cgtgagcgta ccggcgcagg catgatggat
    34561 tgcaaaaaag cgctgactga agcgaatggc gacattgagc tggcaatcga aaacatgcgt
    34621 aagtccggcg ctatcaaagc ggcgaaaaaa gcaggcaacg tggctgctga cggcgtaatc
    34681 aaaaccaaaa tcgacggtaa cgtcgctttc attctggaag ttaactgcca gactgacttc
    34741 gtggctaaag atgctggctt ccaagcattt gctgacaaag tgctggacgc cgctgttgct
    34801 ggcaaaatca ctgacgtaga agtcctgaaa gcgcagttcg aagaagagcg cgttgctctg
    34861 gttgcgaaaa tcggcgagaa catcaacatt cgtcgcgtcg cttccctgga aggcgacgtg
    34921 ctgggttctt accagcacgg tgcgcgcatc ggcgttctgg ttgccgctaa aggcgctgac
    34981 gaagagctgg ttaagcagct ggcgatgcac gttgcggcaa gcaagccgga attcgttaag
    35041 ccggaagacg tgtctgctga cgtggtagag aaagagtacc aggtacagct ggacatcgcg
    35101 atgcagtccg gtaagccgaa agaaatcgca gagaaaatgg ttgaaggccg catgaagaaa
    35161 ttcaccggcg aagtttctct gactggtcag cctttcgtca tggaaccgag caaatctgtt
    35221 ggccaactgc tgaaagagca caacgctgac gtgactggct tcatccgctt tgaagtgggc
    35281 gaaggcattg agaaagtcga gactgacttt gcagcagaag ttgctgcgat gtctaagcag
    35341 tcctgatttt cctgaggagc cgcctgaggg cggcttcttt ttgcgcctct cttgtaaaat
    35401 cagccgacgc ctggcgtctg cgctgaaatg cgacgtacaa tgtcgccgga attaactcat
    35461 atcaatcgtt gacagtctca ggaaagaaac atggctacca atgcaaaacc cgtctataaa
    35521 cgcattctgc ttaaattaag cggcgaagct ctgcagggta cggaaggctt cggtattgat
    35581 gcaagcatac tggatcgtat ggctcaggaa atcaaagaac tggttgaact gggtattcag
    35641 gttggtgtgg tgattggcgg tggtaacctg ttccgtggcg cgggtctggc aaaagcgggg
    35701 atgaaccgcg ttgtgggcga ccacatgggc atgttggcca ccgtcatgaa cggcctggca
    35761 atgcgtgatg cgcttcaccg cgcctatgtg aacgcccgcc tgatgtcggc aattccttta
    35821 aacggcgtgt gcgacaacta cagttgggcc gaggctatta gcctgctgcg taataaccgt
    35881 gttgtgattc tgtctgcagg tacgggtaac ccgttcttca ctaccgactc tgcggcctgt
    35941 ctgcgcggga tcgaaattga agcggatgtc gtactgaaag cgaccaaagt ggatggtgta
    36001 ttcactgccg atccggcaaa agatccttcc gcgaccatgt acgatcagct gacctacagc
    36061 gaagtgctgg ataaagagct gaaagtgatg gatctggcgg cgttcacgct ggctcgtgac
    36121 cacaaactgc cgattcgtgt tttcaacatg aacaaaccgg gcgcgctgcg tcgtgtggtg
    36181 atgggcgaaa aagaagggac gttaatcacg gaataattcc cgtgagcgcc aaatacgggt
    36241 aagattctgt tctattgacg ggtcttatta cctggcagaa attaaacgag actatactta
    36301 gcacatcttt atattgtgtg accgtctggt ctgactgaga ctagttttca aggattcgta
    36361 acgtgattag cgatatcaga aaagatgctg aagtacgcat ggaaaaatgc gttgaagcgt
    36421 tcaaaaccca aatcagcaaa gtgcgcacgg gtcgtgcttc tcccagcctg ctggatggta
    36481 ttgtcgtaga atactatggc actccgaccc cgctgcgcca gttggcaagc gtaacggtag
    36541 aagactcccg taccttaaaa attaacgtgt ttgaccgttc tatggggcca gccgttgaaa
    36601 aagcgatcat ggcgtcagac ctcggtttga atccaagctc tgcgggcacc gatattcgcg
    36661 ttccgctgcc gccgctgacc gaagaacgtc gtaaagatct gacgaaaatt gtccgtggag
    36721 aagcggagca ggcgcgtgtc gccgtacgta acgtccgccg tgatgcgaac gataaagtaa
    36781 aagctctgct gaaagataaa gcgatcagtg aagatgacga tcgtcgctct caggaagaag
    36841 tacagaaaat gaccgacgcg gcaattaaga aagtggatgc ggcgttggca gataaagaag
    36901 cagaactgat gcagttctga ttgatctgta cgcagatata aactcattcc accgctaaac
    36961 ctggcggatg agtggtgtac aaagcgccgc gcagaagaca ttatcaggtc tcctgtgcgg
    37021 cgttttgctt tttattccgt ttcaacactt ctggacgttt catgaagcaa ttaaccattc
    37081 tgggctcgac cggctctatt ggttgcagca cactggacgt ggtgcaccat aatcctgata
    37141 gctttcgcgt tatcgcgctg gtggcgggta aaaatgtcgc ccgcatggcg gagcagtgcc
    37201 tggagttctc gccgcgttat gccgtgatgg acgatacgtc gagcgcagaa cagctcaaaa
    37261 taatgcttca gcagcatggc agccgcaccg aggttctgag cggtcagcag gctgcctgtg
    37321 agatggcggc gcttgatgag gttgggcatg tgatggcggc cattgtgggc gcggctggtt
    37381 tactgccgac cttggcggcg atccgcgcag ggaagacgat tctgctggcg aataaagaat
    37441 cgctggtgac ctgcgggcgg ctgtttatgg acgaagtgaa acgcagcaac gcccggcttt
    37501 tacccgtcga tagcgaacat aacgcgattt ttcagagttt gccgcaatct attcagcata
    37561 atctgggata cgctgacctt gagcaaaatg gcgtaacgtc gattttgctt accgggtctg
    37621 gtggcccgtt tcgtgaaacg cccatgtgcg atctggcagc gatgacgccg gatcaggcat
    37681 gtcgtcatcc gaactggtcg atggggcgaa aaatctccgt cgactccgcc accatgatga
    37741 ataaaggtct ggaatacatt gaagcgcgtt ggttatttaa tgccagcgca cgtcagatgg
    37801 aagtgttgat ccatccgcaa tcggtcattc attcgatggt gcgttatcag gacggcagcg
    37861 tcctggcgca gcttggagaa cctgacatgc gtacgcctat tgcgcatacg atggcatggc
    37921 cgaatcgcgt cacgtccggc gcgcagccgc tcgatttttg caaactcagc gcgctgacgt
    37981 ttagcgcgcc agattatcag cgttatcctt gcctgaagct ggcgatggag gcgtttgagc
    38041 aaggtcaggc ggcaacgacg gcgctcaatg cggcaaacga aatcaccgtt gccgcgtttc
    38101 tggcgcaaca gattcgtttt accgatatcg ccgggctcaa tttagcggtg ctggagagga
    38161 tggatttaca cgaaccggca agcgttgatg acgtattgca ggttgacgcc atcgcgcgtg
    38221 aagtagccag aaaacaagtg atacggctct cacgctgacg attatcccgc gacagaagat
    38281 cgtgctattt gttagcgttg ggcttcggtg atatagtctg cgccacctga tcgcaggttt
    38341 ttggcttttt tcggtcaggt tagccgtggt tttacacggc ttttttgtgg atacacaaaa
    38401 tcattcagga cgcatcggga cggcaggcgg atacgttccc ggcgtgcgca gacagcgcac
    38461 gacaggggcg atgacgcgca gtcattcgcg aagcgaaccg aagagaatgt gtataaaggc
    38521 ttcagtattc ctgagtaccg ctaaatcctt tcagggacaa aaaacgcgtt atgttgtctg
    38581 caactcaacc agtaagcgaa aatttgccag cacatggctg ccgtcatgtt gccataatta
    38641 tggatggcaa tggccgctgg gcgaaaaagc aagggaagat ccgggccttt gggcataaag
    38701 ccggggcgaa gtccgtccgg cgagcggtct cttttgctgc caataacggt attgatgcgt
    38761 taacgctgta tgcctttagt agtgaaaact ggaaccgacc agcgcaggaa gtgagcgcgt
    38821 taatggagct gtttgtgtgg gcgctggata gcgaagtcaa aagcctgcac cgccataacg
    38881 ttcgcctgcg tattatcggc gatatcagcc gatttaactc acgtttacaa gaacgtattc
    38941 gcaaatcaga agcgcttacc gcccataata cggggctaac gttgaatatc gctgcgaatt
    39001 acggcggacg ttgggatatt gtccagggag tccgacaact ggcggagctg gtgcaggctg
    39061 gagtgctgcg ccccgatcag attgatgaag agagactagg ccagcaaatc tgtatgcatg
    39121 agctggcgcc tgtggattta gtaattagga ctgggggaga gcatcgcatt agtaactttt
    39181 tgctttggca aattgcctat gccgaacttt actttacgga tgttctctgg cccgatttcg
    39241 atgaacaaga ctttgaaggt gcgctgcatg cctttgctaa tcgagagcgt cgtttcggcg
    39301 gtaccgagcc tggtgatgac aaagcctgat gggggtcgct tttgctgaag tatcgcctga
    39361 tttctgcttt tgtgttaata cccgcggtca tcgctgcgct ttttttattg ccgccggtgg
    39421 ggttcgccat tattacgctg gttgtctgta tgctggccgc gtgggaatgg gggcagttaa
    39481 gcggtttcgc cgcgcgttca cagcgggttt ggctggcggt gctgtgtggt ctgttattgg
    39541 cgctgatgtt atttttgttg cctgagtatc atcacaacat tcgtcaaccg ctggttgaga
    39601 tgtcgctttg ggcatcgtta ggatggtggg ttgtcgcgct actgctggtg ctattttatc
    39661 ccggttcggc ggcaatctgg cgcaactcaa aaacattgcg tctcattttc ggtttgttaa
    39721 ctattgtgcc atttttctgg ggcatgctgg cgctgcgcgc ctggcactat gacgagaatc
    39781 attacagtgg cgcaatatgg ttactctatg tcatgatcct ggtctgggga gcggactctg
    39841 gcgcgtatat gtttggtaaa ttgtttggca aacataagct ggcgccgaag gtttccccgg
    39901 gtaaaacctg gcaagggttt atcggcgggc ttgctacggc tgccgtgatc tcatggggtt
    39961 acggtatgtg ggcgaatctg aatgttgcgc ctgttatctt gctgatttgc tctgtggtgg
    40021 cggctctggc ttctgtactg ggcgacctca ccgagagtat gtttaagcgc gaagcaggaa
    40081 ttaaggatag cggccacttg atcccaggcc atggcggcat tctggaccga attgacagtc
    40141 tgacggctgc cgtaccggtc tttgcttgcc tgttgttact ggtgttcagg acgctctaac
    40201 ggaaggtttt atgctgagta ttctctggaa tctggctgca ttcatcatcg cactgggcgt
    40261 gctgatcact gtgcatgaat ttggtcattt ctgggttgcc cggcgctgcg gtgtgcgagt
    40321 tgagcgcttt tccatcggtt ttggcaaagc gctctggcgt cgtaccgatc ggtacggcac
    40381 cgagtatgtc atcgccctga tcccgctggg cggctacgtc aaaatgctgg atgagcgcgc
    40441 cgaaccggta gcgccggaat tgcgtcgtca cgccttcaat aacaaaacgg tgggccagcg
    40501 cgccgcaatt attgccgcag gtccggttgc gaacttcatt tttgctatct ttgcttactg
    40561 gctggtcttt atcatcggcg tccctggcgt tcgtccggtc attggcgaaa taacgcccaa
    40621 ctcgattgct gcgcaggcgc aaattgcgcc tggtacggaa cttaaagccg ttgatggtat
    40681 cgaaacccct gattgggatg ccgtgcgttt acaactggtg tccaaaattg gcgatcagca
    40741 gacgacggtg agcgtcgcgc cgtttggcag cgaccagcgg caggacaaaa cgcttgattt
    40801 acgtcactgg gcatttgagc ctgataagca agatcctgta tcttctttag ggattcggcc
    40861 ccgcgggcca cagattgaac cggtactgtc agaagtgcag gcgaattccg cagccagtaa
    40921 agcgggtttg caagcaggcg acaggatcgt taaagtcgat ggtcagccgt taacgcagtg
    40981 gatgaaattc gtgacgtttg tacgtgataa tcccggtaag ccgttagcgt tagagattga
    41041 aaggcagggg agcgccttgt cgttgacgtt aacgccggat acgaaatcgg ttaacggaaa
    41101 ggcggaaggg tttgcaggcg tggtgcctaa aattattcct ctgccggaag agtacaagac
    41161 tatacgccag tatgggcctt ttagcgccat cctcgaagcc acggataaga cgtggcagtt
    41221 gatgaagctg acggtcaata tgctgggtaa attgataacc ggtgatgtga aactgaacaa
    41281 cctcagtggg ccgatttcta tcgctcaggg ggctgggatg tcagcggagt tcggggtgat
    41341 ttattacctg atgttccttg cgctaatcag cgtgaactta gggataatta acctgtttcc
    41401 gctgcccgtt cttgacgggg gtcatctgct gttcctggcg attgaaaagc ttaagggcgg
    41461 gccggtatcc gagcgggttc aagactttag ttatcgcatt ggctcgattt tgctggtgtt
    41521 gttaatgggg cttgcacttt tcaatgattt ctctcggttg taagagagtt agttaggaag
    41581 aacgcataat aacgatggcg atgaaaaagt tgctcatagc gtcgctgctg ttcagcagcg
    41641 ccaccgtata cggtgctgaa gggttcgtag tgaaggacat tcatttcgaa ggcctgcagc
    41701 gagtcgccgt tggtgcggct ctcctcagta tgccggtgcg cacaggcgac acggttaatg
    41761 atgaagatat cagtaacacc attcgcgctc tgttcgccac cggcaacttt gaggacgtcc
    41821 gcgtcctgcg cgatggtaat acccttctgg ttcaggtaaa agaacgtccg accattgcca
    41881 gcatcacttt ctccgggaac aagtcggtga aagatgacat gctcaagcaa aacctcgaag
    41941 cgtctggcgt acgtgttggc gagtctctgg atcgcaccac gctgtctgat atcgaaaaag
    42001 gtctggaaga cttttactat agcgtaggta aatacagcgc cagcgttaag gcggtcgtca
    42061 cgccgctacc gcgcaaccgt gttgatctta aactggtgtt ccaggagggc gtatcggcga
    42121 agatccaaca gatcaacatc gtcggtaacc atgcctttag caccgaagaa ctcatttctc
    42181 atttccagtt gcgtgacgaa gtgccgtggt ggaacgtcgt cggcgatcgt aaataccaga
    42241 aacagaagct ggcgggcgac cttgaaacct tgcgcagcta ctatctggat cgcggctacg
    42301 cgcgtttcaa tattgactcc acgcaagtga gtctgacgcc ggataagaaa gggatctaca
    42361 tcaccgtcaa tatcaccgaa ggcgatcagt acaagctttc cggggttcag gtgagcggta
    42421 acctggccgg acattccgct gaaattgaga aactgacgaa aattgaaccg ggcgagctct
    42481 ataacggcac caaagtgacc aaaatggaag atgacatcaa aaagcttctg ggtcgctatg
    42541 gttacgccta tccgcgcgtg cagtcacagc ctgaaattaa cgatgctgac aaaaccgtaa
    42601 aactgcgcgt gaacgtcgat gcgggcaacc gtttctacgt gcgtaagatc cgctttgaag
    42661 gcaacgatac ctcaaaagat tccgttctgc gccgtgaaat gcgccagatg gaaggggcgt
    42721 ggctgggcag cgacctggtt gaccagggga aagagcgtct gaaccgtctc ggcttctttg
    42781 aaaccgtcga caccgacacg cagcgcgttc cggggagccc ggatcaggtt gatgtggtgt
    42841 acaaggtgaa agagcgtaac accggtagct tcaacttcgg tatcggttac ggtacagaaa
    42901 gcggcgtgag cttccaggcc ggcgttcagc aggacaactg gttaggtacc ggttattccg
    42961 tggggattaa cggtaccaaa aatgactacc agacctacag cgaactgtcc gttactaacc
    43021 catactttac cgttgacggc gtgagcctcg gtggtcgtat cttctataac gactttgaag
    43081 cggatgatgc cgacctgtcc gactatacca acaagagtta cggtacggat gtgacgcttg
    43141 gcttccccat caacgagtac aacacgttgc gtgctggtct gggctatgtc cataacaaac
    43201 tgtccaacat gcagccgcag atcgcgatgg atcgttatct tgaatcgatg ggcgaccctg
    43261 atgccagcga ttttgccgct gacgacttca cctttaacta cggctggacc tataacaagc
    43321 ttgaccgtgg ttatttcccg acggacggct cgcgagtcaa cctgacgggt aaggtgacga
    43381 ttccaggttc cgacaacgaa tactacaaag tgtcgctgga taccgcgacc tatgtgccta
    43441 ttgataacga ccacaagtgg gtggttctgg ggcgtactcg ttggggttac ggcgatggtt
    43501 taggcggcaa ggaaatgccg ttctatgaga acttctatgc cggtggttcc agtaccgtgc
    43561 gtggtttcca gtcgaatact atcggcccga aagcggtcta taaaaatggc gcccacacta
    43621 gttgggacga tgatgatgat tacgaagact gtactcagga atcaggctgt aaatcagatg
    43681 atgcggtagg tggtaatgcc atggctgtcg ccagcctgga atttattacc ccgacgccgt
    43741 tcatcagcga aaagtatgcc aactcggttc gtacctcctt cttctgggat atgggtaccg
    43801 tttgggatac gaactgggat ccgtcatctg cgccgtcaga tgtaccggat tacagcgatc
    43861 caggcaacat ccgtatgtcc gcgggtatcg cattacaatg gatgtcccca ttggggccgt
    43921 tggtcttctc ctacgcccag ccgtttaaaa agtacgatgg agacaaagcc gagcagttcc
    43981 agtttaacat tggtaaaacc tggtaattgt tcactgcaaa ggaatgcatt ggtagtgtag
    44041 cgatgacttt tggcgatgcc cccagggatc gccaggccac gcaaagagct gtaccttcgg
    44101 gtgcaaatgg gatggtaagg agtttattgt gaaaaagtgg ttattagctg caggtcttgg
    44161 tttggcgatg gttacgtccg cacaggctgc tgacaaaatt gcaatcgtca acatgggtaa
    44221 tctgttccaa caggttgcgc agaagacggg tgtatccaat acactggaaa acgaatttaa
    44281 aggccgtgcg gctgaactgc aaaaaatgga aaccgatctg caatctaaaa tgcagcgtct
    44341 gcaatccatg aaagcaggta gcgatcgtac taagctggaa aaagacgtga tgtctcagcg
    44401 ccagactttc gcacaaaaag cgcaggcttt tgagaaagat cgcgctcgtc gttccaacga
    44461 agaacgcaac aaactggtga ctcgtatcca gactgcggtg aaaaaagtgg ctaacgacca
    44521 gagtatcgat ctggtggtag acgcaaacac cgttgcttac aacagcagcg atgtgaaaga
    44581 catcaccgct gacgtactga aacaggttaa ataagtaatg ccttcaattc gactggctga
    44641 cttagcagaa cagttggatg cagaattaca cggtgatggc gatatcgtca tcaccggcgt
    44701 tgcgtccatg caatctgcaa caacaggcca cattacgttt atggtaaatc ctaagtaccg
    44761 tgaacactta ggtttatgcc aggcttctgc ggttgtcatg acgcaggacg atcttccttt
    44821 tgccaagagc gcggcgctgg tagttaaaaa tccctacctg acctacgcgc gcatggcgca
    44881 aattttagat actacgccgc aacccgcgca gaatatcgcg ccaagcgccg tgattgatgc
    44941 gacggcaacg ctgggtagca atgtttcagt cggcgcgaat gcggtgattg aatctggcgt
    45001 acaactgggc gataacgtgg ttatcggcgc aggctgtttc gtcggaaaaa atagcaaaat
    45061 cggggcgggt tcacgcttgt gggcgaacgt aacgatttac cacgacattc agatcggtga
    45121 gaattgcctg atccagtcca gtacggtgat cggcgcggac ggttttggct acgctaacga
    45181 tcgtggcaac tgggtgaaga tcccacaact gggccgggtc attattggcg atcgtgtcga
    45241 gatcggcgct tgtaccacca ttgaccgtgg cgcgttggat gatactgtta ttggcaatgg
    45301 cgtgattatt gataatcagt gccagattgc acataacgtc gtgattggcg acaatacggc
    45361 agttgccggt ggcgtcatta tggcgggtag cctgaagatt ggccgttact gcatgattgg
    45421 cggcgccagc gtgatcaatg ggcatatgga aatatgcgac aaagtcacgg taactggcat
    45481 gggtatggtg atgcgtccca tcacggaacc gggcgtctac tcctcaggca ttccgctgca
    45541 acccaacaaa gtatggcgta aaactgctgc actggtgatg aacattgatg atatgagcaa
    45601 gcgtctcaaa gcgattgagc gcaaggttaa tcaacaagac taacgttccg ccttgtagtt
    45661 gccattcttt tccggcctgt cacattcata cgattgcggc aggccgtgtt attattgcct
    45721 ttttgtatat ttggacagga agagtatttt gactactaac actcatactc tgcagattga
    45781 agagatttta gagcttctgc cgcaccgttt tccgttttta ctggtcgatc gcgtgctgga
    45841 ctttgaagaa ggtcgttttc tgcgtgcggt gaaaaatgtc tccgtcaacg agccgttttt
    45901 ccaggggcat ttcccgggca aaccgatttt gccaggcgtg ctgattctgg aagcgatggc
    45961 gcaggcaacc ggtattctgg cgtttaaaag cgttggtaaa ctggaacctg gcgaactgta
    46021 ttatttcgcg ggtattgatg aagcgcgctt taagcgtccg gtggtgccag gcgatcagat
    46081 gatcatggaa gtcactttcg agaaaacgcg ccgtggcctg acccgcttta aaggggttgc
    46141 gctggtcgac ggtaaagttg tgtgcgaagc aaccatgatg tgtgctcgta gccgggaggc
    46201 ctgattcgtg attgataaat ccgtctttat tcatcctacc gccattgtgg aagacggcgc
    46261 tgtaattggc gctaatgccc acattggtcc cttttgtatt gttgggccgc aggtcgaaat
    46321 tggtgaggga accgtactga agtctcatgt ggtcgtaaat ggtcaaacca aaatcggccg
    46381 cgacaacgag atttatcagt ttgcctccat cggtgaagtg aaccaggatc tgaaatatgc
    46441 gggtgagcca acccgtgtgg aaattggcga tcgtaaccgc atccgcgaaa gcgtcaccat
    46501 tcatcgtggt acagtgcagg gcggtgggtt gacgaaggtg ggtagcgata acctgctgat
    46561 gatcaatgcg catgtcgcac atgattgtac ggtaggtaat cgctgtatcc tcgccaacaa
    46621 cgccacgctg gcggggcacg tatcagtcga tgattttgcg atcatcggcg gtatgacggc
    46681 agttcatcaa ttctgcatta tcggtgcgca tgtgatggtc ggcggctgct ccggcgtggc
    46741 gcaggatgtc cctccgtatg tgattgcgca gggtaaccat gcgacgccgt tcggggtaaa
    46801 tatcgaaggg ctgaagcgtc gcggctttag ccgtgaaggg ctggtggcga ttcgtaatgc
    46861 ctacaaactg ttgtaccgca gtggtaaaac gctcgacgaa gcgaagctgg aaatcgctga
    46921 acttgctgaa aagcatccgg aagtgaaggc gtttaccgag ttctttgagc gttcaacgcg
    46981 cggtccgatt cgttaatggc ggcacagcgt cctttaacga ttgccctggt cgccggtgaa
    47041 acgtccggcg atattcttgg cgcaggctta attcgtgcgc tgaaagcgcg cgtacccaac
    47101 gcccgttttg tgggcgttgc ggggccgcgt atgcaggccg aagggtgtga agcctggtac
    47161 gagatggaag agctggcggt catgggcatt gttgaagtgc tcggacgttt acgccgtttg
    47221 ttgcatatcc gcgccgatct gacccgccgt tttaccgaac tcaagcccga tgtctttgtc
    47281 gggattgatg cccctgattt caatattacc ctcgaaggta atctgaaaaa acaagggatt
    47341 aagaccattc attatgtcag cccgtccgtt tgggcctggc gacagaaacg cgttttcaaa
    47401 ataggcagat ccacccatat ggtgttggct tttctgcctt tcgaaaaagc gttttacgat
    47461 aaatttaacg tcccgtgccg ctttatcggt cacaccatgg cggatgccat gccgctggac
    47521 ccggataaaa atgcggcgcg cgacgtgctg ggtatcccgc atgacgccca ttgtctggcg
    47581 ctactgccag gcagccgtgg cgcggaagtg gaaatgctca gcgccgactt cctgaaaacc
    47641 gcacaattgc tgcgacagcg ctatcccgat ctggaagtgg tagtgccgct ggtgaacgcg
    47701 aaacgccgcg agcagtttga aaaaattaaa gcggaggttg cgccggatct cgccgttcat
    47761 ttgctggacg gcatggcgcg cgaggcgatg atcgccagcg acgcggcgtt gctggcctca
    47821 ggcacggcgg cactggagtg tatgctggca aaatgcccga tggtagtggg gtatcgtatg
    47881 aagcccttca ctttctggct ggcgaaacgt ctggtgaaaa cggagtatgt gtctttgcct
    47941 aacctgctgg cgggaagaga attagtcaaa gagctgttgc aggaagagtg cgaaccgcaa
    48001 aaactcgccg aagcgctgtt gccgctactg gcgaacggta aaaccagcca tgcgatgcac
    48061 gacaccttcc gtgaattgca tcagcagatc cgctgtaatg ccgatgagca ggcggcagat
    48121 gccgtcctgg agttagcaca atgatcgaat ttgtttatcc acacacccat ttagtggcgg
    48181 gtgtggatga agtgggccgt ggcccgctgg tgggcgccgt agtgaccgcc gccgtgatcc
    48241 tcgatccggc gcgtccgatc gtcggtctga atgattccaa aaaattgtct gaaaagcgtc
    48301 gtctgtcatt gtatgacgag attaaagaaa aggcgttaag ctggagtctg ggacgcgcgg
    48361 aagcgcatga aattgatgag ctgaatattt tgcacgccac catgctcgcc atgcagcgcg
    48421 ctgtcgctgg tctgcatatt gcgccagaat atgtgctgat cgacggcaat cgctgtccgg
    48481 agctgcctgt gccgtcaatg gccgtggtga aaggcgacag ccgcgtggcg gagattagcg
    48541 cggcgtctat tctggcgaaa gtcacccgcg acgcagaaat ggcggcgctg gatatcgttt
    48601 ttcctcagta tggctttgcg cagcacaaag gctatccaac cgcttttcat ctggaaaagt
    48661 tggcccagta tggcgcgacg gcgcaccacc gacgcagttt tgcgcctgtt aaacgcgctc
    48721 tgggacttgt gtcctgattc ttgtatcgag aaatctgaag atgtctgaac cacgtttcgt
    48781 tcacctgcgg gtgcacagcg actactctat gatcgatggg ctggcgaaga ccgggccgct
    48841 ggtgaaaaag gcggcctcat taggtatgcc tgcgctggcg atcaccgatt ttaccaacct
    48901 ctgcggtctg gtgaagttct acggagcggg tcatggcgcg ggcattaaac ccatcgtcgg
    48961 ggcggacttt aacgttcaca acgaactgct gggagatgag ctgactcatc tgacggtact
    49021 ggcggcgaat aatacgggat accagaacct gacgttgctg atctcgaaag cgtatcagcg
    49081 cggctacggc gcggcaggcc cgattatcga gcgcgactgg ctggtagagc ttaaagaagg
    49141 tttgatcctg ctttccggcg ggcgcatggg cgacgtaggc cgctgtctgc tacgcggcaa
    49201 ccaggcgctg gtggaggagt gcgttgcttt ctatgaagcg cattttcccg atcgctactt
    49261 cctggaactg atccgtaccg gcagacagga tgaagagacc tatctccatg ctgcggttga
    49321 gctggctgag gcacgtggtt tgccggttgt cgcgacaaac gatgtccgtt tccttgaaag
    49381 cgatgatttt gacgcccatg agattcgtgt cgcgattcac gacggtttca cgctcgacga
    49441 tcctaaacgt ccacgcaatt attcaccgca gcagtatatg cgcagtgaag aagaaatgtg
    49501 cgagctgttc tccgatattc cggaggcgct ggaaaatacg gtggagattg ccaaacgctg
    49561 caacgtaacg gtgcgtctgg gtgaatattt cctgccgcag ttcccgaccg gcgatatgac
    49621 caccgaagat tatctggtca aaaaatcgaa agaggggctg gaagagcgtc tggctttcct
    49681 gtttccggac gaagaagagc gcaaaaagcg tcgcccggaa tatgacgagc gtctggatat
    49741 tgaactacag gttatcaacc agatggggtt ccctggctac ttcctcatcg tgatggagtt
    49801 tatccagtgg tcaaaagata acggcgtgcc ggtagggccg ggacgtggtt ccggggccgg
    49861 ttcgctggtg gcctacgcgc tgaaaattac cgaccttgat ccgctggaat ttgacctgct
    49921 gttcgaacgt ttcctgaacc cggaacgtgt ctcgatgcct gacttcgacg ttgacttctg
    49981 tatggagaaa cgcgaccagg tgattgagca cgtcgcagac atgtacgggc gtgatgcggt
    50041 atcgcagatt atcaccttcg gtacgatggc ggcgaaagcc gttatccgcg atgtgggccg
    50101 cgtgctgggg catccgtacg gttttgtcga tcgtatctcg aagctggtgc cgcccgatcc
    50161 gggcatgacg ctggcaaaag cctttgaagc ggaaccgcaa ctaccggaaa tttacgaggc
    50221 ggatgaagag gtcagagcgc tgatcgatat ggcgcgtaag ctcgaaggcg tcacgcgtaa
    50281 cgccggtaag cacgctggcg gcgtggtcat cgcgccgacc aaaattaccg actttgcgcc
    50341 gctgtactgc gatgaagagg gcaagcatcc ggttacccag tttgataaaa gcgacgtgga
    50401 atatgccggg ctggtgaagt tcgacttcct cggtttgcgt acgctgacta tcatcaactg
    50461 ggcgctggag atgatcaaca agcggcgggc gaagaatggc gagccaccgc tggatatcgc
    50521 cgccattccg ctggacgata aaaaaagctt cgacatgctg caacgctcgg aaaccacggc
    50581 ggtcttccag cttgaatcgc gcggtatgaa agacctgatc aagcgtctgc aacctgactg
    50641 ctttgaagat atgatcgcgc tggtggccct gttccgtccc ggcccgttgc agtcagggat
    50701 ggtagataac tttatcgatc gtaagcacgg tcgtgaagaa ctctcttacc cggacgttca
    50761 gtggcagcat gaaagcctga agccggtact ggagccgacc tacggcatca ttctgtatca
    50821 ggaacaggtg atgcagattg cccaggtact ttccgggtat actctcggtg gcgcggatat
    50881 gctgcgtcgt gcgatgggta agaaaaagcc ggaggagatg gccaaacagc gttccgtttt
    50941 tgaagagggc gcgaaaaaga acggtatcga cggcgaactg gcgatgaaaa tctttgacct
    51001 ggtggagaaa ttcgccggtt acgggtttaa caaatcgcac tccgccgctt atgcgctggt
    51061 ttcttatcag acgctatggc taaaggcgca ctatccggct gaatttatgg cggcggtgat
    51121 gactgccgat atggacaaca ccgagaaggt cgtcggcctg gtagacgagt gctggcggat
    51181 gggactgaaa attctgccgc cggatattaa ctccggattg taccatttcc acgttaatga
    51241 tgagggcgag atcgtctacg gcatcggcgc gatcaaaggc gtcggcgaag ggccgatcga
    51301 agcgatcatc gacgcgcgta atcagggcgg ctatttccgc gaactgtttg atctgtgcgc
    51361 gcggaccgac accaaaaagc tcaaccgccg ggtgctggaa aagctgatca tgtccggggc
    51421 gttcgaccgc ctggggccgc accgcgccgc gctgatgaac tcattgggcg atgcgctgaa
    51481 agccgccgac cagcacgcca aagcggaagc tatcggtcag gcggatatgt tcggcgtact
    51541 ggcggaagag ccggagcaaa tcgaacaatc ctatgccagc tgccagccgt ggccggagca
    51601 ggtggtgtta gatggggaac gtgaaacgtt ggggctgtac ctgacgggcc accctatcaa
    51661 tcagtattta aaagaaattg agcgctatgt cggcggggta aggctcaaag acatgcatcc
    51721 gacagaacgt ggtaaagtca ccacggctgc ggggctcgtg attgccgcaa gggttatggt
    51781 caccaagcgc ggcaatcgta tcggcatctg tacgctggat gaccgttccg ggcgtctgga
    51841 agtgatgtta tttaccgacg cgctggataa ataccagcag ttgctggaaa aagaccgcat
    51901 acttatcgtc agcggacagg tcagctttga tgacttcagc ggggggctta aaatgaccgc
    51961 ccgcgaagtg atggatattg acgaagctcg cgaaaaatac gctcgcgggc ttgctatctc
    52021 gctgacggac aggcaaattg atgaccagct tttaaaccga ctccgtcagt ctctggaacc
    52081 ccaccgctcg gggaccattc cagtacatct ctactatcag agggcggatg cgcgtgcgcg
    52141 gctgcgtttt ggcgcaacgt ggcgtgtctc tccgagcgat cgtttactta acgatctgcg
    52201 tggcctcatt ggttcggagc aggtggaact ggagtttgac taatacagga atactatgag
    52261 tctgaatttc cttgattttg aacagccgat agcagagctg gaagcgaaaa tcgattctct
    52321 gactgcggta agccgccagg atgagaaact ggatattaat atcgatgaag aagtccatcg
    52381 cctgcgcgaa aaaagcgtag aactgacgcg caaaatcttc gccgatctcg gcgcatggca
    52441 ggtagcccaa ctggcgcgcc atccgcagcg tccgtacacc ttggattatg tccgtctggc
    52501 gtttgatgag tttgatgagc tggcgggcga tcgcgcctat gctgatgaca aagccatcgt
    52561 cggcggtatc gcgcgtctgg aagggcgacc ggtgatgatc attggtcatc agaaaggtcg
    52621 tgaaaccaaa gaaaaaattc gtcgtaactt tggcatgcca gcgccggaag gctaccgcaa
    52681 agcgctgcgc ctgatggaaa tggctgaacg cttcaacatg ccgattatca ccttcatcga
    52741 caccccgggc gcttaccctg gcgtgggcgc ggaagagcgt ggtcagtctg aagctatcgc
    52801 ccgcaacctg cgtgagatgt ctcgtctgaa cgtaccggtc atctgcaccg tgattggcga
    52861 aggcggctcc ggcggcgcat tggcgattgg cgtgggtgat aaagtgaata tgctgcaata
    52921 cagcacctat tccgttatct ccccggaagg ttgcgcctct attttgtgga agagcgccga
    52981 caaagcgcca ttggctgctg aagcgatggg catcatcgcg ccgcgtctga aagagctgaa
    53041 gctaatcgat tccatcattc cggagccgct gggcggcgcg caccgtaatc cggaagcgat
    53101 ggcggcgtcg ctaaaagcgc agctgctgga agatttagcc gatctcgatg tgttaagcac
    53161 cgatgattta aaaaaccgtc gttaccagcg tttgatgagc tacggttacg cctaatcatt
    53221 tacctcattt ctcccaggag gccggataat ccggcctctt ttttgtctat ggaaa
//
LOCUS       DAJVKX010000014        52886 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000014 DAJVKX010000000
VERSION     DAJVKX010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 52886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52886
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.014"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            92..1318
                     /locus_tag="OPY25_000783"
     CDS             92..1318
                     /locus_tag="OPY25_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HCS0926469.1"
                     /translation="MKQITFTPRHHQLTNTNTWTPDSQWLVFDVRPSGASFTGKTIER
                     VNVHTGDVEVIYRAVQGAHVGVVTVHPADNYYVFIHGPENPDETWHYDFHHRRGVIAT
                     PGGVTNLDAMDITAPYTPGALRGGSHVHVFSPNGELVSFTYNDHVLHECDPALDLRNV
                     GVAAPYGPVTVPVQHPREYSGSHWCVLVSRTTPAPRPGSDDINRAYEEGWVGNRQIAF
                     IGDTLSLTGQKVPELFIVDLPCHENGWKQAGDTPLTGTESTMPSPPLGVVQRRLTFTH
                     QRVYPGLTNEPRHWVRSNPQATAIAFLMRDDNGVAQLWLISPQGGEPRQLTHHATGVQ
                     SAFNWHPSGKWLGLVLENRIACCDAQSGKIDFLTARHDNPPSADAVVFSPDGRHVAWM
                     EEVKGFRQLWVTETGR"
     gene            complement(1320..1652)
                     /locus_tag="OPY25_000784"
     CDS             complement(1320..1652)
                     /locus_tag="OPY25_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HCS0926470.1"
                     /translation="MIKNVWLTLIIWNGMLLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGNDETNWGTKSLAILDMPFTAVMDTILLPWDIFRKDSSVRSRVEKSEEETKMTNAVI
                     PPAKMPPP"
     misc_feature    1895..1968
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            1962..2375
                     /gene="ibpA"
                     /locus_tag="OPY25_000785"
     CDS             1962..2375
                     /gene="ibpA"
                     /locus_tag="OPY25_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HCS0926471.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNLLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIELERVIPEANKPRRIEIN"
     gene            2485..2907
                     /gene="ibpB"
                     /locus_tag="OPY25_000786"
     CDS             2485..2907
                     /gene="ibpB"
                     /locus_tag="OPY25_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462708.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HCS0926472.1"
                     /translation="MRNYDLSPLLRQWIGFDKLANALQNSGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLDIQLEGTRLTVKGTPEQPENEPKWLHQGLVMQPFSLSFTLAEN
                     MEVSGATFTNGLLYIDLTRNEPETIPPQRIAINERSAS"
     gene            3101..4762
                     /locus_tag="OPY25_000787"
     CDS             3101..4762
                     /locus_tag="OPY25_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HCS0926473.1"
                     /translation="MSDIALTVSVLALVAVVGLWIGNIKVRGVGFGIGGVLFGGIIVG
                     HFVDQAGVTLSGDMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     MGGLVTAILHKIFAIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPVDLVDQMGMSY
                     AMAYPFGICGILLTMWLMRLIFRVNVEAEAQKHESSLANGHSLIQTMNIRVENPNLNN
                     MAIQDVPILNSDKIICSRLKRDDTLMVPSPGTIIQAGDLLHLVGQPTDLHNAQLVIGK
                     EVDTSLSTRGTDLRVERVVITNEKVLGKRIRDLHFKERYDVVISRLNRAGVELVASSD
                     ASLQFGDILNLVGRPASIDAVANVVGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFVP
                     GFPVALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKS
                     GGDFVDTLTQGEGLSWIGYGIFITAIPLITVGLLARIFAKMNYLTLCGMLAGSMTDPP
                     ALAFANNLHATSGAAALSYATVYPLVMFLRIITPQLLAVIFWGMG"
     gene            5205..5552
                     /locus_tag="OPY25_000788"
                     /pseudo
     CDS             5205..5552
                     /locus_tag="OPY25_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462706.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
     gene            5542..5904
                     /locus_tag="OPY25_000789"
     CDS             5542..5904
                     /locus_tag="OPY25_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HCS0926474.1"
                     /translation="MPDSRKARRQNDPGLQPERTSLAWFRTLLGYGALMALAVRHYWH
                     QAGFLFWVSISVLAIVAVILWRYTLSRNLMDVAHSDFSETHVMRDKFLISLAVLSLAI
                     LFAVTHIRQLIAFIGDFI"
     gene            5901..6431
                     /locus_tag="OPY25_000790"
     CDS             5901..6431
                     /locus_tag="OPY25_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCS0926475.1"
                     /translation="MTGRQDIVVSNDQIQVVVNRQNSQRPQQLYRNLQRLGIRNVHFI
                     PLLEHDRNGMLTEDSLCSADWGRFLNSVFDIWVREDIQRISVRLFDETLQQWCGGRNG
                     AKTPDKAPLSAECQKCSLLRFCGGGCPEHRDSQGKNQLCEGYQTFFNYSSPHMRVMRD
                     LLKQHRSPEELMAMLR"
     gene            complement(6513..7835)
                     /gene="dsdA"
                     /locus_tag="OPY25_000791"
     CDS             complement(6513..7835)
                     /gene="dsdA"
                     /locus_tag="OPY25_000791"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HCS0926476.1"
                     /translation="MENILKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTE
                     QDVNAAHDRLARFAPYLAKAFPQTAAAGGIIESDVVAIPAMQKRLEKEYGQTIDGEML
                     LKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYS
                     IAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAV
                     EQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPC
                     GVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTA
                     ADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGP
                     QRICASVAYQQRHGFSQTQLGNATHLIWATGGGMVPEDEMEQYLAKGR"
     gene            complement(7853..9190)
                     /gene="dsdX"
                     /locus_tag="OPY25_000792"
     CDS             complement(7853..9190)
                     /gene="dsdX"
                     /locus_tag="OPY25_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
                     /protein_id="HCS0926477.1"
                     /translation="MHAQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGAMM
                     GIGPLEMVTAIENGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSAD
                     VIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTHTSLLKLAIPLCTALMAVHCVVPP
                     HPAALFVANKLGADIGSVIVYGLLVGLMASLVGGPLFLKFLGNRLPFKPVPTEFADLE
                     VRAENTLPSLGATLFTVLLPIGLMLVKTVAELNMAKDGTLYTLLEFIGNPITAMFIAV
                     FVAYYILGLRQHMGMSALLTHTENGFGAIANILLIIGAGGAFNAILKSSGLADTLAVI
                     LSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDVSPEIIAIAIGS
                     GTIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII"
     gene            9416..10339
                     /gene="dsdC"
                     /locus_tag="OPY25_000793"
     CDS             9416..10339
                     /gene="dsdC"
                     /locus_tag="OPY25_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DsdC"
                     /protein_id="HCS0926478.1"
                     /translation="MEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPS
                     AVSHRINQLEAELGIQLFVRSHRKVELTHEGKRVFWALKSSLDTLNQEILDIKNQELS
                     GTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAP
                     SAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGTDEWHS
                     WAQHFAVNLPDSSGIGFDRSDLAVIAAMNHIGVAMGRKRLVQKRLDSSELIAPFGDMR
                     LKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV"
     gene            10403..11488
                     /locus_tag="OPY25_000794"
     CDS             10403..11488
                     /locus_tag="OPY25_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HCS0926479.1"
                     /translation="MVKILGGVVFKPLIASLILTSAVVYAKPMPLTAARYAQQLGVGM
                     DVDWARTERGIREFDPLVVRDFKAKGLTHVRIRVAGAPTEARLIHLRKLVEACEYYGV
                     IPIIAYQADAYKTDPSASHEKELINWWSVVARYFGQTSPLLGFDLIYEPADKLNHNMA
                     SLNRVYDKTIRLIHAIDPQRMIFVAPRMRAAPEDLSALKLPAQSQNYVLAEWHIFPWG
                     PLKSGGKYPWTSGTTAEKAAIRARINAAVRWQHKTGHASWVGGWAPGESIKMTPIASQ
                     FAFARFMACELKKAHIPYAINADTQFYDGEEGAWRPAQEPLLNAMIAPECETPGKKPG
                     EGNVKPSVPDAISVTPAAASTPRSAIP"
     gene            complement(11415..12599)
                     /gene="emrD"
                     /locus_tag="OPY25_000795"
     CDS             complement(11415..12599)
                     /gene="emrD"
                     /locus_tag="OPY25_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HCS0926480.1"
                     /translation="MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMAQALNVREGA
                     VQSVMAAYLLTYGVSQLFYGPLSDRVGRRPVILVGMSIFMVATLIAMTTHSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYEGTQLRHANSLLNMGILVSPLLAPLIGGLLDTLWN
                     WRACYAFLLVLCAGVTFSMARWMPETRPAGAPRTRLIASYKTLFGNGAFNCYLLMLIG
                     GLAGIAVFEACSGVLMGAVLGLSSMVVSILFILPIPAAFFGAWFAGRPNKRFSALMWQ
                     SVICCLLAGLMMWIPGWFGVMNVWTLLIPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLAWLSAMLPQTGQGSLGLLMTLMGLLILACWLPLASRISHQGQ
                     TV"
     gene            complement(12802..13662)
                     /locus_tag="OPY25_000796"
                     /pseudo
     CDS             complement(12802..13662)
                     /locus_tag="OPY25_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462698.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
     gene            complement(13755..13844)
                     /gene="tisB"
                     /locus_tag="OPY25_000797"
     CDS             complement(13755..13844)
                     /gene="tisB"
                     /locus_tag="OPY25_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HCS0926481.1"
                     /translation="MSVVDITILILKLIVAALQLLDAVLKYLK"
     gene            complement(13841..13955)
                     /locus_tag="OPY25_000798"
                     /pseudo
     CDS             complement(13841..13955)
                     /locus_tag="OPY25_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009325922.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14478..14576
                     /gene="ivbL"
                     /locus_tag="OPY25_000799"
     CDS             14478..14576
                     /gene="ivbL"
                     /locus_tag="OPY25_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HCS0926482.1"
                     /translation="MNPSMLNATLLTTAPSRAVVVVRVVVVVGNAP"
     gene            14683..16371
                     /gene="ilvB"
                     /locus_tag="OPY25_000800"
     CDS             14683..16371
                     /gene="ilvB"
                     /locus_tag="OPY25_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HCS0926483.1"
                     /translation="MASSGTTSTPQRFTGAEFIVHFLERQGIRIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTESKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRNINELPQVMSDAFRLAQS
                     GRPGPVWIDVPKDVQTATIELDALPSPAEKSPPPEFSAESIREAAAMINAAKRPVLYL
                     GGGVINAPTRVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGARSTNFILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPHIEAQPREAWHQLVADLQQEFPCGIPQENNPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPGNKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNDALGLVHQQQSLFYKQGVFAATYPGSINFMQIAAGFG
                     LDTCDLNNEADPQAALQAIIRRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            16375..16665
                     /gene="ilvN"
                     /locus_tag="OPY25_000801"
     CDS             16375..16665
                     /gene="ilvN"
                     /locus_tag="OPY25_000801"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HCS0926484.1"
                     /translation="MQKQSHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QGSDQSRIWLLVNDDQRLEQMISQIDKLEDVAKVVRNQSDPTMFNKIAVFFE"
     gene            complement(16667..17452)
                     /locus_tag="OPY25_000802"
     CDS             complement(16667..17452)
                     /locus_tag="OPY25_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCS0926485.1"
                     /translation="METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLSQ
                     DDDPLPLTLLGGYIVMVNKPASSTNMPLPAKKTHHRDDLPVAILAAGLVRENDLVFFD
                     NGPEMPLVISMIPDDITFTGICYSHRVFIALNEKPNATAILCGGTYRAKSDAFYDANN
                     PSALDSLNPRKVFISASGVHEHFGVSWFNPDDLAAKRKAMERGLRKILLARHALFDEV
                     APASIGPLSAFDVLISDRPLPTDYAVHCRNGSVKVITPDSESE"
     gene            17766..18686
                     /gene="rbsK"
                     /locus_tag="OPY25_000803"
     CDS             17766..18686
                     /gene="rbsK"
                     /locus_tag="OPY25_000803"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCS0926486.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCQLIVLQLEVQLETVYHAIEFGKKHGIEVL
                     LNPAPALRELDMSYACKCDFFVPNETELEILTGMPVDTYDHIRAAARSLVDKGLNNII
                     VTMGEKGALWMTRDQEVHVPAFRVNAVDTSGAGDAFIGCFAHYYVQSGDVEAAMKKAV
                     LFAAFSVTGKGTQSSYPSIEQFNEYLSLNE"
     gene            18717..20033
                     /gene="fucP"
                     /locus_tag="OPY25_000804"
     CDS             18717..20033
                     /gene="fucP"
                     /locus_tag="OPY25_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HCS0926487.1"
                     /translation="MNDKNIVQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIVGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     AAGILLGKYLVFSEGESLEKQMAGMNAEQVHNFKVLMLENTLEPYKYMIMVLVVVMVL
                     FLLTRFPTCKVAQTASHKRPSALDTLRYLASNARFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASTFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAVVPA
                     IQGYVADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRGNLAEVAAS"
     gene            20045..21058
                     /locus_tag="OPY25_000805"
     CDS             20045..21058
                     /locus_tag="OPY25_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCS0926488.1"
                     /translation="MTTRITLWRELFSEQPRILLENDDFTVTAFRYASGVEGLKIQNS
                     RGHLVILPWMGQMIWDVQFDGHDLTMRNMFRQPKPAAEVVATYGCFAFHSGLLANGCP
                     SPEDTHPLHGEMPCAAMDDAWLELEGDSLRVTGRYEYVMGFGHHYQAQPAVVMRKSSA
                     LFDIQMTVTNLASVAMPLQYMCHMNYAYVPNATFRQNIPDTALKLRESVPAHVKPTAQ
                     WLAFNQRLLQGEASLATLNEPGFYDPEIVFFADELDKYTDTPEFSMIAPDGTTFVTRF
                     ASAELNYVTRWILYNGDQQVAAFALPATCRPEGFLAAQRNGTLLQLEPQQTRTFTVTT
                     GIV"
     gene            21212..21802
                     /gene="uhpA"
                     /locus_tag="OPY25_000806"
     CDS             21212..21802
                     /gene="uhpA"
                     /locus_tag="OPY25_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HCS0926489.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAVKLAAGRQDPLTKRERQVEEKLAQGMAVKEIAA
                     ELGLSPKMVHVHRANLLEKLGVSNDVELAHRMFDGW"
     gene            21802..23304
                     /gene="uhpB"
                     /locus_tag="OPY25_000807"
     CDS             21802..23304
                     /gene="uhpB"
                     /locus_tag="OPY25_000807"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HCS0926490.1"
                     /translation="MNTFFSRLITVVACFFIFSAAWFCLWSISLHLVERPELAALLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLVYWLAQEVALAHLPLLMIGGVLTLLPVALTSR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLGQGEAAWNALLLTLTGGLTLAPICLVFWH
                     YLTSTTWLPLGPSLVSQPVNWRGRHLIWYLLLFIVSLWLQLGLPAELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWHDHPVDLLLSLLAQSLTGLLLGAGIQRL
                     RELNQSLQKELARNHRLAERLLETEESVRRDVARELHDDIGQTITAIRTLAGIVQRLA
                     ADNGGVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLAQAIRSLLREMELESRG
                     IVSHLDWRIDETALSESQRVTLFRVCQEGLNNIVKHANASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSHQQGFGLTGMRERVSALGGTLTISCTHGTRVSVSLPQRYV"
     gene            23314..24642
                     /locus_tag="OPY25_000808"
     CDS             23314..24642
                     /locus_tag="OPY25_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0926491.1"
                     /translation="MLSFLKAPANAPLITDKHEVDARYRYWRRYILITIWLGYALFYF
                     TRKSFNAAAPEILASGILTRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGVVNILFGFSTSLWAFALLWALNAFFQGFGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPLVMAAVALHYGWRVGMMVAGLLAIGVGMVLCWRLRDRPQAIGLPPVG
                     DWRHDALEVAQQQEGAGLSRKEILAKYVLSNPYIWLLSLCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVSMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQAACFFTTGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLSGWPLAKVLEIWHWTGFFAVIAIAAGISALLLLPFLNAQAPRETHEA"
     gene            24785..26176
                     /gene="uhpT"
                     /locus_tag="OPY25_000809"
     CDS             24785..26176
                     /gene="uhpT"
                     /locus_tag="OPY25_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HCS0926492.1"
                     /translation="MLAFLNQVRKPTLDLPLNVRRKMWFKSFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYRLSMTELGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGAGSTSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRFGSDSPE
                     SYGLGKAEELFGEEISEEDKETEENEMTKWQIFVEYVLKNKVIWLLCFSNIFLYVVRI
                     GIDQWSTVYAFQELKLSKEVAIQGFTLFEVGALVGTLLWGWLSDLANGRRALVACVAL
                     ALIIATLGVYQHASNQYVYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFDYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDAAAIGCICLMAMVAVMEERK
                     IRREKKIQQVNIA"
     gene            26369..26821
                     /locus_tag="OPY25_000810"
     CDS             26369..26821
                     /locus_tag="OPY25_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HCS0926493.1"
                     /translation="MIWLILATFVVVFIVGFRVLTSDTRRAIRRLSERLNIDVVPIES
                     MIDQMGKTAGGEFLQYLHRPDESHLQNAAQVLLIWQMVIVDGGDQNLQRWHRLLQKAR
                     LAAPITDTQVRLALGFLREMEPDMQEINAFQLRYNAFFQPEEGVHWLH"
     gene            27174..27917
                     /locus_tag="OPY25_000811"
     CDS             27174..27917
                     /locus_tag="OPY25_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0926494.1"
                     /translation="MKTLSKSSHIPLYQQVVEWIRESIYSGELVEDDRIPSEFQIMDM
                     LEVSRGTVKKAVDQLVREGVLVQVQGKGTFVKKENVAYPLGEGLLSFAEALASQKINF
                     TTSVITSRLEPANRFVAEKLSIKPGQDVLFLKRLRCIGDEKVMLIENRINIDLCPGII
                     DVDFTRENLFSAIERLSDKKISFSESRYAAKLIGNERGHYLDIGEDAPVLHLEQLVFF
                     SRGLAIDFGNVWLKGNKYYLGTILQRLDA"
     gene            27935..28408
                     /locus_tag="OPY25_000812"
                     /pseudo
     CDS             27935..28408
                     /locus_tag="OPY25_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462683.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            28405..28692
                     /locus_tag="OPY25_000813"
     CDS             28405..28692
                     /locus_tag="OPY25_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCS0926495.1"
                     /translation="MSKMILFVCATGVATSTAVAEKVMEYCKDNGLDVNYSQTNVASL
                     PNNTDGAALVVSTTKVPYELDIPVVSGLPIITGVGEDKVLEKIVSILKGQA"
     gene            28768..30126
                     /locus_tag="OPY25_000814"
     CDS             28768..30126
                     /locus_tag="OPY25_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCS0926496.1"
                     /translation="MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALR
                     SSLIVGIGFVGIYAIFDILTSNVGPAAQAMVERTGISLPVVDLGWPPLAAITWGSPIA
                     PFVIPLTMLINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSFVLGLSAAAIAA
                     IVVLKLADWSAPLVAKYFGLEGISLPTLSSVVFFPIGLLFDKIIDKIPGVNRIHIDPE
                     NVQKKMGIFGEPMMVGTILGVLLGIIAGYDFKHILLLGISIGGVMFILPRMVRILMEG
                     LLPLSEAIKKYLNAKYPGRDDLFIGLDIAVAVGNPAIISTALILTPISVFIAFLLPGN
                     KVLPLGDLANLAVMASMIVLACRGNIFRAVITAIPVIIADLWIATKIAPFITGMAKDV
                     NFKMAEGSSGQVSSFLDGGNPFRFWLLEIFNGNIIAIGLIPVLALVIYGVFRLTKGTV
                     YA"
     gene            30119..31603
                     /locus_tag="OPY25_000815"
     CDS             30119..31603
                     /locus_tag="OPY25_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HCS0926497.1"
                     /translation="MPDYHAALVIDIGTTNCKVSCYSCHDVSVLEVRKFPTPTISSDK
                     GEVDLDIEALWQALRLVMAELVASVPFPVKNISIASFGESGVFVDKEGVILTPMLAWY
                     DRRGESYLSSLSKAEAEELYSITGLPPHSNYSAFKMRWLLDNYSLHERKDICWLHAPE
                     VLLWRMTGAKKTEISLASRTLCLDIARRTWSRNAAGILGIPFGVLAPLIKPGEVAGWV
                     TATLRQELGLPHEVKVTLAGHDHMVGARALQMQPGDVLNSTGTTEGILLLNTQPTLDV
                     QARRDKLANGCYSDGEFFTLFASLPVGGYALEWVKKTFRLTDKEISTGLEKVMEQYLK
                     PSWSVEHVPVFIPHLRGSGSPHKNQHTRGLLFGLTDSLPPESLLESVFIGLAMEFAHC
                     HGCFNIPAGRTVKVIGPAVKNPYWLQLKADILQCPIEAIAFDETVSLGALLIACPNVV
                     PPTVPVAERYFPDAVRSAKLKIYQQQWLSFYQFKLRQEGAFIGE"
     gene            31666..32526
                     /locus_tag="OPY25_000816"
                     /pseudo
     CDS             31666..32526
                     /locus_tag="OPY25_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462679.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase"
     gene            32536..32805
                     /locus_tag="OPY25_000817"
     CDS             32536..32805
                     /locus_tag="OPY25_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HCS0926498.1"
                     /translation="MIRQKVRVMNSTGLHARPAATLAKIVKKYQSSLTLVNNDKEIPI
                     KGMMSILGAGVKGNTMIDLICDGQDELAFMDELKSAFADGFGESV"
     gene            complement(32896..33219)
                     /locus_tag="OPY25_000818"
     CDS             complement(32896..33219)
                     /locus_tag="OPY25_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HCS0926499.1"
                     /translation="MSAKTKFKSPAFEAIHSAASGLFSVDAIPQETMRSFDTACLSSI
                     KDLQPLEIKALREELNVSQSVFARYLNTSVSTVQKWESGAKRPSGMSLKLLNVVQKHG
                     LKVLV"
     gene            complement(33203..33561)
                     /locus_tag="OPY25_000819"
                     /pseudo
     CDS             complement(33203..33561)
                     /locus_tag="OPY25_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462676.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            33777..34970
                     /gene="nepI"
                     /locus_tag="OPY25_000820"
     CDS             33777..34970
                     /gene="nepI"
                     /locus_tag="OPY25_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HCS0926500.1"
                     /translation="MNENIAEKFRADGVARPNWSAVFAVAFCVACLITVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFSSLFITQIIQATDRRYIVILFAVLLTASCLMV
                     SFANSFTLLLLGRACLGLALGGFWAMSASLTMRLVPARTVPKALSVIFGAVSIALVIA
                     APLGSFLGGIIGWRNVFNAAAVMGVLCVIWVVKSLPSLPGEPSHQKQNMFSLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFDVDGLTLVLLSFGIASFVGTSFSSYVL
                     KRSVKLALAGAPLLLALSALTLIVWGSDKTVAAAIAIIWGLAFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAVGGYALDNFGLLSPLALSGGLMLLTALVVAAKVR
                     ITPMS"
     gene            complement(35030..36412)
                     /locus_tag="OPY25_000821"
     CDS             complement(35030..36412)
                     /locus_tag="OPY25_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCS0926501.1"
                     /translation="MRYRFPDNFWWGSACSALQTEGDSLNGGKSQTTWDVWFERQPDR
                     FHQGIGPAETSTFYRHWKQDIALLKQLKHNSFRTSLSWARLIPDGVGEVNPQAVSFYN
                     HVIDELLAQGITPFITLFHFDMPMVMQEKGGWENRDVVEAFGRYAQTCFTLFGDRVKH
                     WFTFNEPIVPVEGGYLYDFHYPNVVDFKRAATVAYHTVLAHSTAVRAWRAGRYDGEIG
                     VVLNLTPSYPRSQHPADVQAAHHADLLFNRSFLDPVLKGEYPAELVALLKTYDQLPAC
                     QPGDRQLIADGKIDLLGINYYQPRRVKCRDTAVNPQAPFMPEWLFDYYDMPGRKMNPY
                     RGWEIYAPGIYDIITNLRDNYGNPRCFISENGMGVENEQRFVQAGQIHDDYRIDFISE
                     HLKWLHKGISEGCHCLGYHMWTFIDNWSWLNGYKNRYGFVQLDLATQTRTVKKSGEWF
                     AATAEHNGFD"
     gene            complement(36518..36811)
                     /locus_tag="OPY25_000822"
     CDS             complement(36518..36811)
                     /locus_tag="OPY25_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926502.1"
                     /translation="MKRKTLLLIATLVALPGVTYADSPFSSLQSAHEKNTILKDLRKM
                     CTPKGALTDEAWEKKIMTSEGNQQHIREAMIAIERNNQHNYWQALGKVECPEM"
     gene            37008..37265
                     /locus_tag="OPY25_000823"
     CDS             37008..37265
                     /locus_tag="OPY25_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014341509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0926503.1"
                     /translation="MRRIEIVLGELERLTRGLCLADLAQETAFTAEAIGFNLGLARNS
                     VSKDLNQLWNDGLAIKSRGRPVYFLASPGAGNVAGTSAGRV"
     gene            37237..39807
                     /gene="dagR"
                     /locus_tag="OPY25_000824"
     CDS             37237..39807
                     /gene="dagR"
                     /locus_tag="OPY25_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014341510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DagR"
                     /protein_id="HCS0926504.1"
                     /translation="MLGRQLEESEREVRSVADVLPHEEHYAPDDPFTSLIGYDRSLRD
                     AVEKGRAAVLYPHGLHVLLTGPSGVGKTFFAELMHRFACEQASGAIPPLVYFNCAEYA
                     HNPELLSSHLFGHRQGAFTGANEHKTGLVEQADGGYLLLDEVHRLSYEGQEKLFSILD
                     KGEYRPLGVSSQPRSISVRLICATTEPVGSALLRTFQRRIQVCIDLPGIRQRSVEEQI
                     ELIVGFLQRESRKIERTVSIDKPLLLWLLNKPLEGNIGQLKSDIQFLCAQAWASGMTE
                     HNDTLQLDKRLAEMSVNPTPEQRLLVDTLFDGKARLNIDARTLPALKTSLATGAEIEE
                     SDLFYSFLTREYVNLRNSNVPPAETLAILKNKLSSIFEYGLYSRDSVAHPPRYGDQIE
                     ERVTLLIGCVEQVLGFSLPENLVNPLRKHFLALIGYVQRGLIPQLYSSSLILDRCKDE
                     YDNATLLCRKINELLHIQCPATEVVWLCLFLKECRHYRQRIDASPDCGVILIAHGATT
                     ATSQAQYVNRVLERELFSAIDMPFEQSVHDTLETLTQMIQTRQYRRLILLVGIGSLIH
                     FGSTISKLFQIDVLLMPNITLTSLLEVGLDLSYETSDLPQLTALLQSKNIPCQLCTPQ
                     QENGGKVLVISCITGMGTAEKIKKVLEESFGELMSQDTRMVILDYNEVRSLERVQQAL
                     NASERLAGIVGTFQPGLPDIPFISLEELFSEQGPELVLSLLTPDLSNAERRLEMERSA
                     MRFISALTMESIINHISVLNPQRILKEMEGVFNHLTSSLSLKPSRQVTLRFLIHCCCM
                     VERIVINRKPLQMALERQPNLDARAFSVIKSAFLPIEDAYAIRLSDAEYFYIYELLYS
                     "
     gene            40029..40454
                     /locus_tag="OPY25_000825"
     CDS             40029..40454
                     /locus_tag="OPY25_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCS0926505.1"
                     /translation="MTTTQPLPHILLLTHGGWGQPLCNSLRMVTGEIKGVTEIALMPV
                     DTLGEFYQRVEAVVKTLPEGSLILTDFVGGTTSNVAARLSADYPVAVIAGLNASLLLE
                     ALDRREQGMLTACVDELVEAGRSSCLDVVAHVRQLQQSL"
     gene            40465..40950
                     /locus_tag="OPY25_000826"
     CDS             40465..40950
                     /locus_tag="OPY25_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HCS0926506.1"
                     /translation="MANIVLCRIDSRLIHGQVVTKWVGQSQANRIAVVSDELDADPFM
                     KNIYLMAAPPNIKVDCFGNQSFAAAWKENQLGDGNVLVLFPSLAAVQDAIQLGFDVTR
                     IQVGGLGGGPNRKAVFQNITLDEKDVGILNDLKNRGVQVFFQTIPEDKPQPLDDILKK
                     F"
     gene            41096..41845
                     /locus_tag="OPY25_000827"
     CDS             41096..41845
                     /locus_tag="OPY25_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCS0926507.1"
                     /translation="MDTLLFASLMGLYYWFARLRLGYTFSAMLLQPVVIAVFVGLLLG
                     NMQTAMIIGAGMQLVYLGVTSTPGGNVPSDPALAACISIPIAVKAGMDPNLAIALAIP
                     FGVIGVFLDQLRRTLNAAWVHMADKHAETANMAGIMRCAFLYPALLGLVLRFPVVFAA
                     NYFGQDVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAV
                     LYLKVDIMAMAIFGTCVAFLIKGLAKNEGAA"
     gene            41842..42702
                     /locus_tag="OPY25_000828"
     CDS             41842..42702
                     /locus_tag="OPY25_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462668.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCS0926508.1"
                     /translation="MMSSDVMQHELVERARESGALTKADITKAWFIYWLGAEVSSSYE
                     RLQSLIFCASMTPIIKKLYPQKEEQVEALKRHLNFFNSEQTFGAVIQGISIAMEEQKT
                     RGEPINDSSITGIKTGLMGPLAGMGDSIIWAAVMPLLIAIFIPFAANGSAMGGIIPLI
                     LYPAITLAISYGMVHKGYTLGRDSIIGLLQGGRIKELIYGANVLGLIMMGALSASYVK
                     ITTPLKISALKRSEVVVQQILDSIAPGLLPLAAVFAIYFYLVKKGPRYTTILLSIVAL
                     SIVCSLLGVL"
     gene            42706..43815
                     /gene="dgaE"
                     /locus_tag="OPY25_000829"
     CDS             42706..43815
                     /gene="dgaE"
                     /locus_tag="OPY25_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glucosaminate-6-phosphate ammonia lyase"
                     /protein_id="HCS0926509.1"
                     /translation="MTPNIYQQLGLKKVINACGKMTILGVSSVAPEVMQATARAASAF
                     VEIDALVEKTGELVSRYTGAEDSYITSCASAGIAIAVAAAITHGDRARVALMPDSTGM
                     ANEVVMLRGHNVDYGAPVTSAIRLGGGRIVEVGSSNLAARWQLESAINEKTAALLYVK
                     SHHCVQKGMLSIDDFVQVAQANHLPLIVDAAAEEDLRGWVVSGADMVIYSGAKAFNAP
                     TSGFITGKKTWIAACKAQHQGIARAMKIGKENMVGLVYALENYHQGQTTVTAAQLQPV
                     AEAISAIHGLYADIEQDEAGRAIWRIRVRVNASELGLNAQDVEAQLRGGEIAIYARKY
                     QLHQGVFSLDPRTVAEGEMALIVARLREIAEHAAD"
     gene            43802..44545
                     /locus_tag="OPY25_000830"
     CDS             43802..44545
                     /locus_tag="OPY25_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCS0926510.1"
                     /translation="MQQINFYRQRVAINVLAKDIANAKAIYEAAEGHAVIGVLSAQFA
                     TVEEGVPEVKRWMAEVPSISVGLGAGDPAQYYKAAMIAAHTHPAHVNQTFTGSGFAAG
                     ALAATGGEQTHINALVSPTGTPGEVVISTGVSSSQGMPARVSCEAAVRMMQDMGAHAA
                     KFFPMGGEKSLPELYALATTAARHGMTLIEPTGGISLDNFGIILQTCLEAGVPRVMPH
                     VYSSIIDPQTGNTRPEDIIQLMEIVKALV"
     gene            44781..45722
                     /locus_tag="OPY25_000831"
     CDS             44781..45722
                     /locus_tag="OPY25_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCS0926511.1"
                     /translation="MKKSPTSTPHDAVFKTFLRHPDTARDFLNIHLPHLLRIRCDLTT
                     LKLAPDSFIEKNLRAFYSDVLWSLKTCEGDGYIYVVIEHQSTPDAHMAFRLMCYATAA
                     MQRHLDAGHKTLPLVIPMLFYHGAKSPYPFSLCWLDEFGDPALARQLYATAFPLVDIT
                     VVPDNEIMQHRRIAMLELVQKHIRQRDLMGLVERLAVLLITGNANDSQLKALFNYLLI
                     QHGSTPRFGKFIREVARCVPQHKERLMTIVDRIRESGRRKGKREGVQQGIQQGIHQGK
                     QEEALRIAHTMLEQGIEREMVLMITGLSDEEIKAKRH"
     gene            complement(45765..46667)
                     /locus_tag="OPY25_000832"
     CDS             complement(45765..46667)
                     /locus_tag="OPY25_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HCS0926512.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRL
                     LFAGLILVTFSFMHGDKIFSILKNRKDALSLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFALARRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSGALF
                     WGIASAFAAAFYTTWPSRLIAQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGISFTLPDW
                     LGTLLILSSVILISLDSRRRARAA"
     gene            47173..47868
                     /locus_tag="OPY25_000833"
     CDS             47173..47868
                     /locus_tag="OPY25_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC family protein"
                     /protein_id="HCS0926513.1"
                     /translation="MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVA
                     TGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAG
                     IGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEAEKRYILKVTCNKEDE
                     SAVRQWLLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDN
                     DNITAIHWSIDSQ"
     gene            48088..50814
                     /gene="mgtA"
                     /locus_tag="OPY25_000834"
     CDS             48088..50814
                     /gene="mgtA"
                     /locus_tag="OPY25_000834"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCS0926514.1"
                     /translation="MTDMNIENRKLNRPASENDKQHKKVFPIEAEAFHSPEETLARLN
                     SHRQGLTIEEAGERLKVYGRNEVAHEQVPPVLVQLLQAFNNPFIYVLMALAGVSFITD
                     YWLPLRRGEETDLTGVLIILTMVSLSGLLRFWQEFRTNRAAQALKKMVRTTATMLRRG
                     PGNIGAVQEEIPIEELVPGDVVFLAAGDLVPADVRLLASRDLFISQLILSGESLPVEK
                     YDVMADVAGKDSEQLPDKDKSLLDLGNICLMGTNVTSGRAQAVVVATGSRTWFGSLAK
                     SIVGTRTQTAFDRGVNSVSWLLIRFMLIMVPVVLLINGFSKGDWVEASLFALAVAVGL
                     TPEMLPMIVSSNLAKGAIAMSRRKVIVKRLNAIQNFGAMDVLCTDKTGTLTQDNIFLE
                     HHLDVSGVKSSRVLMLAWLNSSSQSGARNVMDRAILRFGEGRIAPSTKARFIKRDELP
                     FDFVRRRVSVLVEDAQHGDRCLICKGAVEEMMMVATHLREGDRVVALTETRRELLLAK
                     TEDYNAQGFRVLLIATRKLDGSGNNPTLSVEDETELTIEGMLTFLDPPKESAGKAIAA
                     LRDNGVAVKVLTGDNPVVTARICLEVGIDTHDILIGTQVEAMSDAELASEVEKRAVFA
                     RLTPLQKTRILQALQKNGHTVGFLGDGINDAPALRDADVGISVDSAADIAKESSDIIL
                     LEKDLMVLEEGVIKGRETFGNIIKYLNMTASSNFGNVFSVLVASAFIPFLPMLAIHLL
                     IQNLMYDISQLSLPWDKMDKEFLRKPRKWDAKNIGRFMLWIGPTSSIFDITTFALMWY
                     VFAANNVEAQALFQSGWFIEGLLSQTLVVHMLRTQKIPFIQSRATLPVLLTTGLIMAI
                     GIYIPFSPLGAMVGLEPLPLSYFPWLVATLLSYCLVAQGMKRFYIKRFGQWF"
     gene            50836..50928
                     /gene="mgtR"
                     /locus_tag="OPY25_000835"
     CDS             50836..50928
                     /gene="mgtR"
                     /locus_tag="OPY25_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtR"
                     /protein_id="HCS0926515.1"
                     /translation="MNRSPDKIIALIFLLISLLVLCLALWQIVF"
     gene            51129..51607
                     /locus_tag="OPY25_000836"
                     /pseudo
     CDS             51129..51607
                     /locus_tag="OPY25_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462661.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(51930..52610)
                     /locus_tag="OPY25_000837"
     CDS             complement(51930..52610)
                     /locus_tag="OPY25_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family protein"
                     /protein_id="HCS0926516.1"
                     /translation="MSTPANFNGQRPAIDANDAVMLLIDHQSGLFQTVGDMPMPELRA
                     RAAALAKIATLCNMPVITTASVPQGPNGPLIPEIHANAPHAQYVARKGEINAWDNADF
                     VQAVKATGRKTLIIAGTITSVCMAFPAISAVAEGYKVFAVIDASGTYSKMAQEITMAR
                     VVQAGVVPMDTAAVASELQRTWNREDAAEWADVYTKIFPAYQLLIESYTKAQEVVKNN
                     ELLDSQRA"
BASE COUNT        12115 a        13267 c        14586 g        12918 t
ORIGIN      
        1 cgggcctggc tatcccaacg atacgctaaa gcctgaaagt gaagcccgtg tgcagtatga
       61 tgacgagcat cgtctcttat caggacatcc catgaaacaa atcaccttta cgccgcgcca
      121 tcaccagctt accaacacca atacctggac acctgacagc cagtggctgg tctttgatgt
      181 gcggccttca ggcgcgtcat ttacgggcaa gactattgag cgtgtcaatg tgcataccgg
      241 cgacgtggag gtgatttatc gcgccgtgca gggcgcgcat gtcggtgtgg tgacggtgca
      301 tcctgccgac aattactatg tgtttattca tggccctgaa aaccctgatg agacgtggca
      361 ttacgatttc caccaccgtc ggggcgttat tgcaacgccg gggggcgtga ctaacctcga
      421 tgcgatggat attactgcgc cgtatactcc cggcgcgctg cgcggcggca gccacgtcca
      481 tgtatttagc ccgaacggcg agctggtgag ttttacctat aatgaccacg ttctgcatga
      541 gtgcgatccg gcgctggatc tgcgtaatgt cggcgtggcc gcgccgtatg ggccggtaac
      601 ggtgccagtt cagcatccgc gcgaatacag cggtagccac tggtgcgtac tggttagccg
      661 cacgacgcct gcgccgagac ctggcagcga tgacattaac cgcgcctatg aagagggctg
      721 ggtgggcaac cgccagatcg cctttattgg cgatacgctg tcgctgacgg gccaaaaagt
      781 cccggagttg tttattgtcg atttaccgtg tcatgaaaac ggctggaaac aggcaggcga
      841 cacgccgctg acgggaaccg aatcaacaat gccatcgccg ccgttgggcg tagttcagcg
      901 gcgtcttacc tttactcacc agcgtgttta tcctggactc actaacgaac cacgccactg
      961 ggtacgcagt aatccgcagg cgacggcgat cgcctttttg atgcgggacg ataacggcgt
     1021 agcgcaactg tggctgatat cgcctcaggg aggcgagccc cggcagttaa cgcatcatgc
     1081 gaccggcgta cagtcagcgt ttaactggca tccgtcgggt aaatggctgg gactggtgct
     1141 ggaaaatcgg attgcctgct gcgacgcaca aagtgggaag atcgacttct taaccgccag
     1201 gcacgacaac ccgccgtctg cggacgccgt cgttttttca ccggatgggc gacacgtcgc
     1261 atggatggaa gaggtgaaag gtttccgtca gctatgggtg acggaaaccg ggcgataaat
     1321 cagggaggag gcatcttcgc cggggggatg acggcattgg tcattttcgt ctcctcctcg
     1381 cttttctcga cgcgcgatct taccgaactg tctttgcgga agatgtccca cggcagaagg
     1441 atcgtatcca tcacggcggt aaacggcata tccaggatgg ccaacgattt ggtgccccag
     1501 tttgtctcat cgttaccgat catcgtagcg ctggcgcgcg tgccaggata agtaccctct
     1561 ttaccgccgg tgtgcgacat gacgcttgaa caaccgccta ataaaagcat cccattccat
     1621 attatcagcg ttaaccacac gttttttatc atcactcatt catctgttgg ttgtcgttat
     1681 ttgcatgatg agttatagcg atccgttgct aaaaataaca tcaccagtac gtggcactgt
     1741 ggcggtaatc gcactttaac aatcagtgct gtcccaacca gtctatgcaa tagccaataa
     1801 actgcaaaaa aaagtcggat taaaatactt gaaaagtacg tattcagacc catttataag
     1861 acgtagtgaa tagaagggca cgcctgatgg gtgttctggc aatcctggcc tgtccatgat
     1921 ggaaggtctg acattctcgc tgatttcagg agtttatgat tatgcgtaac tttgatttat
     1981 ccccgctgta ccgttctgcc attggttttg atcgtctgtt taacctgctt gaaaataacc
     2041 aaagccaaag taatggcggc taccctccgt acaacgttga gctggtagac gaaaaccact
     2101 accgcatcgc cattgccgtt gccggtttcg cggaaagcga actggagatt actgcccagg
     2161 ataatttact ggtggtaaaa ggcgctcatg cggacgagca gaaagaacgt acttacctgt
     2221 atcagggcat tgccgagcgt aactttgagc gtaagttcca gttagcggag aacattcacg
     2281 ttcgtggcgc aaacctggtc aacgggctgc tgtatatcga actggagcgc gtgattccgg
     2341 aagcgaacaa accgcgccgt atcgaaatta actgattccg tcgggtcgcg ttgcgcggcc
     2401 tgtcatccca tgctcgccgt cagggagcat attcgcacgt aaagtgtgaa ggtaaaaact
     2461 cgcttcttag aaggagaaat gattatgcgt aactacgatt tatccccact gttgcgtcaa
     2521 tggatcggtt ttgacaagct ggccaatgcg ctgcaaaaca gcggcgaaag ccagagcttc
     2581 ccgccctata acatcgaaaa aagcgacgat aaccattatc gcattacctt agcgttagcc
     2641 ggtttccgtc aggaagatct ggatattcaa ctggaaggca cgcgcctgac ggtgaaaggc
     2701 acgccggaac agccggaaaa cgagcccaaa tggttacatc agggcctggt catgcagcct
     2761 tttagcctga gctttacgct ggctgaaaat atggaagttt ccggcgcgac gtttaccaac
     2821 ggcctgctgt atattgattt aacccgtaac gagccggaaa ccattccgcc gcagcgtatc
     2881 gccattaacg aacgctccgc aagctaataa gctccttgcc ttgccccgcc agagatggcg
     2941 gggctttttt gtgccacgaa aaagggtaag acgttgccga agtcaggacg tctgtgcggt
     3001 tttgtaatat gagaatgtgc gccatgctgt atatatgcct taacagttca gtcataatcc
     3061 ctataaattg aaatgttact cacagggaag agaagatgag atgagtgata tcgcattgac
     3121 ggtcagcgtt ctggcgttgg tggcggttgt cggtttatgg atcggcaaca ttaaagtgcg
     3181 cggtgtcggc tttggtattg gcggtgtgtt gttcggcggt attatcgtcg gccacttcgt
     3241 cgatcaggct ggggtgacgc tgagcggcga tatgctgcac tttatccagg agttcggcct
     3301 gatccttttt gtttatacca tcggcataca ggtggggccg gggtttttcg cctcgctgcg
     3361 cgtttccggg ctacgtctga atctgtttgc cgttctgatt gtgattatgg gcgggttggt
     3421 caccgcgatt ctgcataaaa ttttcgctat tccgctgccg gtagtgctgg ggattttctc
     3481 cggcgcagtc accaatacgc ctgcgttagg ggcgggtcag caaatcctgc gcgatctggg
     3541 aacgccagtg gatctggtag atcagatggg gatgagctat gcgatggcgt atccgtttgg
     3601 catctgcggt attttgctca ccatgtggct gatgcggctg atttttcgcg ttaacgtcga
     3661 ggcggaggcg cagaagcacg aatcctctct cgctaacggc cattcattaa ttcagacaat
     3721 gaatatccgt gtcgagaatc cgaacctcaa taatatggct atccaggatg tgccgatcct
     3781 gaacagcgat aaaatcattt gctcacgcct gaaacgcgat gacacgctga tggtgccgtc
     3841 gccggggacg attatccagg caggcgacct gctgcacctc gtcggccaac ctaccgacct
     3901 gcataacgcg caactggtga tcggtaagga agtggacacc tcgttgtcga cgcgcggcac
     3961 ggatttacgt gtcgagcgtg tggtcatcac caacgaaaaa gtgctcggca aacgtatccg
     4021 cgatttgcac tttaaagagc gttatgacgt ggttatctcc cgccttaacc gcgcgggcgt
     4081 tgagctggtc gccagcagcg acgctagcct gcagtttggc gacattctca atctggtggg
     4141 gcgtcctgcc tcgattgatg cggtagccaa tgtggtcggc aacgcgcagc aaaaactcca
     4201 gcaggtgcag atgctgccgg tgtttatcgg catcggatta ggggttctgc ttgggtcaat
     4261 cccgttgttt gtgccgggat tcccggtcgc gttaaaactg gggctggccg gcgggccgtt
     4321 gatcatggcg ctaattttgg ggcgtatcgg cagcatcggt aagctgtact ggtttatgcc
     4381 gccgagcgcc aacctcgcgc tgcgtgaatt aggcatcgtt ttgtttctgg cggtcgttgg
     4441 actgaaatcc ggcggcgatt ttgtcgatac gctgacacag ggcgaaggat taagctggat
     4501 tggctacggt attttcatca ccgctattcc gctgattacc gtcggtttgc tggcgcgaat
     4561 ttttgccaaa atgaactacc tgacgctgtg cgggatgctg gccggttcga tgaccgatcc
     4621 gccagcgctg gcatttgcca acaatcttca tgccaccagc ggcgcggcgg cgctctctta
     4681 cgcgaccgtc tatccgttag tgatgttcct gcgtattatc acgccacaac tgctggcggt
     4741 gattttttgg ggaatgggtt agcgcctgat ggcgcgttgc ttatccggcc tatgcactgt
     4801 gttaaatcca ggctggataa cgcgcgccgc accggtcaca cttctgctct tcttcttatc
     4861 tctttcctca atgaacgtgc taatcagcgt aatggcaacg agcataattc caattttttc
     4921 agttagttat caatcttcat cgcctttttt ttcgtcgcaa cgggtagttt ttcagctttt
     4981 aattcggcaa taatgccttt cctggcggtg gcgctgaaaa aggtcgcaac tgaaatgaaa
     5041 aatagcggca atgagcgcgg ttgcgccgaa acacgtcacc agtgaactac agttattttg
     5101 caataagatt cccttgctgc gggataatgt gaagcatatc agcaacaacg tgagtggtat
     5161 tctgaaaacg aacgggaata cataagaacg taaaaggagt cgtcatgaag atttcccgcc
     5221 tcggagaagc gccggattat cgcttctcac tggcaaatga gcgcaccttt ctggcgtaga
     5281 ttcgcacctc gctgggattt ctggcggcag gcgtcggtct tgatcagctc gccccggatt
     5341 ttgccacgcc ggtgatccgt gaactgctgg cgctactgtt gtgtctgttt gcgggcggcc
     5401 tggcgattta tggctatcta cgctggttac gtaatgaaaa agcgatgcgc ctgaaagagg
     5461 atttgcctta tacccatagc ctgttgatca tcagcgttat tttgatgatt gtcgcggtga
     5521 tagtgatggg gctggtactg tatgccggat agtcgtaaag cccgtcggca gaacgatccg
     5581 ggactgcaac cggagcgtac gtcgctggcc tggtttcgca cgctgctggg atacggggcg
     5641 ttaatggcgt tagccgtcag gcactactgg catcaggcgg ggttcttgtt ctgggtgtca
     5701 atcagcgttc tggcgatagt ggcggtgatt ctttggcgtt ataccctgag tcgtaatttg
     5761 atggatgtcg cgcatagcga tttttccgaa actcatgtca tgcgtgacaa atttttgatc
     5821 tccctcgcgg tgttgtcgct cgcaatcctg tttgctgtta cccatattcg ccaacttatt
     5881 gcatttatcg gggattttat atgacaggac gtcaggacat tgtcgtgagt aatgaccaga
     5941 ttcaggtcgt cgtaaatcgc cagaatagcc agcgccctca gcaactgtac cgtaacttac
     6001 aacggctcgg cattcgcaat gtccatttta tcccattgtt ggaacatgac cggaacggaa
     6061 tgttgaccga ggattcattg tgttcagcag actgggggcg gtttttaaat agcgtatttg
     6121 atatttgggt acgtgaagat attcagcgta tctcggtccg cctttttgat gagacgctac
     6181 agcagtggtg cggcggcagg aatggcgcta aaacgccgga caaggcgccg ctaagcgctg
     6241 aatgtcagaa gtgctcttta ttacgatttt gcggcggcgg atgccctgag catcgggata
     6301 gccaggggaa aaatcagctt tgcgagggct accagacctt ttttaactac tcctcgccgc
     6361 atatgcgggt gatgcgggat ttactgaaac agcatcgctc gccggaggag ttgatggcga
     6421 tgctgcgtta acgtcacagg cctgataagc gtagcgccat caggcgatgg cgtgccggat
     6481 ggcgctgccg tctttccggc actaagcgag tattagcgtc cttttgccag gtattgttcc
     6541 atttcatcct ccggcaccat gccgcccccg gttgcccata tcagatgcgt cgcgttgccg
     6601 agctgcgtct gactgaatcc atgcctttgc tgatacgcga cggaggcgca aatgcgctgt
     6661 ggcccggcca tccccgccag agctgatggc tccagtcgaa ttccttcctc ctgcgccagc
     6721 cagcccagca tgtcatacat tgtttgatcg tctaaggtat agaggccgtc aagcagacgc
     6781 tccattgccc gaccaacaaa gcccgaagcg cgacctaccg ccaggccgtc agccgccgtc
     6841 aggttatcaa taccgatatc ttgtactgag atggcatcgt gcagaccggt ataaacgccg
     6901 agtaacatgc agggtgaatg ggtcggttcg gcaaagaaac agtggacgtt gtcgccaaac
     6961 gccagtttca ggccaaaggc gacgccgcca gggccgccgc caacgccgca cggcagataa
     7021 acaaacagtg ggtggctggc gtcaacgacg cgtccctgct gcgcgaattg cgctttcaga
     7081 cgctgacccg ctaccgcata gcccagaaat agcgtgcgag agttttcatc atcgataaag
     7141 aaacagtttg gatcggattg cgctgcttta cgaccctgct caaccgccac gccgtaatca
     7201 tcttcgtatt ccacgaccgt cacgccgtgg ctacgcagct tcgccttttt ccaggcgcgg
     7261 gcgtcggcag acatatgtac cgtcacttta aaaccgatgc aggcgctcat gataccgatc
     7321 gatagcccca gattgccggt tgaaccgacg gcgatactgt actggctgaa gaattgttta
     7381 aattccggcg aaagcaacac gctatagtca tcgtcggtgg ttaacagacc cgcctccagc
     7441 gccagttttt ccgcgtgcgt tagcacctcg tagatgccgc cgcgcgcttt aatggaacca
     7501 gagattgcta ggtgactgtc tttttttaat agcatttcac cgtcgatcgt ttgcccatac
     7561 tctttttcca gccgtttttg catggccgga atagcgacca cgtcagattc gattatgccg
     7621 ccagcggcag cggtttgcgg aaacgctttt gccagatacg gcgcaaagcg cgccagacgg
     7681 tcatgggcgg cgtttacgtc ctgctccgtc aggccgacat acggtagacc ttgtgcaaga
     7741 gaggtggcgc ccgggttaaa ccaggtggtt tctttgaggg cgaccagatc ctcgaccaaa
     7801 ggataccggg cgatgagctt tagtatgttt tccatagtac gtctctttac gatcagatga
     7861 taaaggaaag caggaatgtg ccagccagtg caacgacaga tgcgataaac gtggccgtcg
     7921 tatagtattt aaacgtttca ttcagcgtag cgccgcaata ctgcttgacc agccagaaca
     7981 gggaatcggt cacgatcgtg cagccaatgg tgccggaacc gatggcaata gcgatgatct
     8041 ccgggctaac gtcaggatag agcggcagca tgggcgcaac aatcgcggtg gcgcccatca
     8101 tcgccaccgt cgcagagccg accgccgcgt gcagaatcag cgctaccagc catgccagca
     8161 gaatcgggtg catatgcata tttgagagga tcaccgccag cgtgtccgcc agtccgctac
     8221 ttttgagaat ggcgttgaac gcgccgcccg cgccgataat cagcaggatg ttcgcaatgg
     8281 cgccaaagcc gttttcggtg tgggtaagta gcgcgctcat acccatatgc tggcgcagac
     8341 cgagtatgta atacgccaca aagacagcga taaacatcgc ggtgatcgga ttaccgataa
     8401 actccagcag cgtatacaac gtgccgtctt tcgccatatt cagttcagcg acggttttca
     8461 ccagcatcag gccaatcggc agcagaacgg taaacagcgt tgcgcccagc gacggcaggg
     8521 tgttttcggc acgcacttca agatccgcaa actctgtcgg tacgggcttg aacggcagac
     8581 gattacccag aaactttaag aacagcgggc cgccgaccaa tgaggccatc agtccgacca
     8641 gcagaccgta gacaatcacc gagccgatat ccgcccccag tttatttgcg acaaacagcg
     8701 cagccggatg cggcggtacc acgcaatgga cggccatcag cgcggtacac agcggaatgg
     8761 ccagcttcag cagcgaggta tgggtctttt tagcgataga aaacgccagt gggatgagca
     8821 acacgacgcc cacttccacg aacaacgtga ttccgcaaat cagccccacc agtaccatga
     8881 tcacgtcagc agagagccag cggcagcgct ggagcgtaag cccgatgcgt tccgccgcgc
     8941 cggaaacctc catcattttg ccgaggatgg tgccaagacc gataacggcg gccagaaaac
     9001 cgagcgtacc gcctattccg ttttctatcg ccgtgaccat ctccagcggc cctatgccca
     9061 tcatcgcgcc gacaaagaaa ctggcgagca gtaacgccag gaaggggtgg aatttaaact
     9121 tcacgatggt caatacgatt aacacgatgc tgatcagcag cgtgctcact acccagattt
     9181 gagcgtgcat atctcaccta ccctgtgatt aatctgttct tattggacag aaaaacagca
     9241 caccctgaca aacgatataa tttgccattc acatgatgta aattgaatca actatgtgat
     9301 ttccatctaa tattgccttt attttgcgat atggttcatt ttacttcatc tatgtgcgga
     9361 ttttttcagc gcgttttttt acacttcggg aaattaaaag atgactgagg ttgccatgga
     9421 accccttcgc gatacccgaa accgcttact caacggctgg cagttatcca aactctatac
     9481 ttttgaagtc gcggccagac accagtcctt tgctctggcg gcagatgagc tgtcgttaag
     9541 ccccagtgcg gtaagccatc gtatcaatca actggaagcc gagttgggaa tccagctatt
     9601 tgtccgctct caccgtaaag tggagcttac ccatgaaggc aaacgggtat tctgggcgct
     9661 gaaatcgtcg ctggatacgt tgaatcagga aatcctcgat atcaaaaatc aggaactgtc
     9721 cggcacgttg accgtgtatt cacgcccctc tatcgcccag tgctggctgg tgcccgcgtt
     9781 gggggacttt acccgtcgct atccgtcaat ttctctcact atgctgaccg gcaacgataa
     9841 cgttaaccta cagcgtgccg gcattgacct ggctatctat tttgacgatg cgccgtcggc
     9901 gcagctcacg caccattttt taatggatga ggcgattttg cccgtttgca gcccggatta
     9961 cgcccgtcgt ttcgccttgc aggacaacct gaataacctg cggcactgta cgctcttaca
    10021 cgacagacag gcgtggagta acgattctgg caccgatgag tggcacagtt gggcgcagca
    10081 ttttgcggta aatttgccgg attcatccgg cattggcttc gatcgttctg atttagcggt
    10141 gattgccgcg atgaaccata ttggcgtggc gatgggacgt aaacgactgg tgcaaaagcg
    10201 tctcgacagc agtgaactga ttgcgccttt tggtgacatg agactgaaat gtcatcagca
    10261 ttattatgtc accactctgc ctggcaggca gtggccgaaa atcgaggcat ttattcgctg
    10321 gttgcaggaa caggtgtgaa gatttattac gctttgccgc tacacctgcc gggagtgaat
    10381 atgctaaata cgtgctatca ccgtggtaaa aattttaggg ggcgtcgtgt ttaaaccgct
    10441 tattgcctct ctcatactga ccagcgcggt cgtctatgcg aaaccgatgc ctttgacggc
    10501 ggcgcgctat gcgcagcagc ttggcgttgg gatggatgtt gactgggcgc gaacggaacg
    10561 gggtattcgc gagtttgatc cgttggtcgt gcgggatttt aaggcaaaag ggttaacgca
    10621 tgtccgtatt cgtgtggcag gcgcgccgac ggaagcgcgc ctcatccatt tgcgtaagct
    10681 ggtagaggcc tgcgaatact atggcgtcat acccattatt gcctatcagg cggatgcgta
    10741 taaaaccgat cccagcgcca gccatgaaaa ggagctgatc aactggtgga gcgtggtcgc
    10801 gcgctatttt ggtcagacat ccccgcttct ggggttcgat ctcatttatg agcctgccga
    10861 caaacttaat cataatatgg cgtcgctgaa tcgcgtatat gacaaaacca tccgcctgat
    10921 tcacgccatt gacccacagc ggatgatttt cgttgccccc cgcatgcgcg ccgcgccgga
    10981 ggatttatcg gcgcttaaac tgccggcgca aagccagaac tatgtactgg cggagtggca
    11041 catcttcccg tggggacccc tgaaaagcgg cggtaaatat ccgtggacgt caggcacgac
    11101 ggcggaaaaa gcggcgattc gggcacggat taatgccgcg gttcgctggc agcataagac
    11161 cggccatgca agctgggtgg gcggatgggc gccgggagag tcgataaaaa tgacgccgat
    11221 cgcttcacag ttcgcgtttg cccgttttat ggcctgcgag ctgaaaaaag cgcatattcc
    11281 gtatgcgata aacgcggaca ctcagtttta tgacggcgaa gaaggagcgt ggcgtccggc
    11341 gcaggagccc ctgctcaatg cgatgatcgc gccggaatgt gaaacgcccg gcaaaaagcc
    11401 gggcgagggg aatgttaaac cgtctgtccc tgatgcgata tccgtgacgc cagcggcagc
    11461 cagcacgcca agatcagcaa tcccataagg gtcatcagca atcccagact gccctgaccg
    11521 gtttgcggca gcattgccga aagccacgcc agtacgccgg aaccaatatt ttgcagcccg
    11581 ccgaccagcg cgccagcggt gcctgcgagg aacggaaacg gctccatcgc gccgctggtg
    11641 gccagtggaa ataacatccc ggcgccgaag aaaaacagcg cagcggggat gagtagcgtc
    11701 cagacgttca tcacgccaaa ccagccggga atccacatca taaggcctgc cagcagacag
    11761 caaataactg actgccacat cagggctgag aagcgtttat tcgggcgtcc ggcaaaccag
    11821 gcgccgaaga acgccgccgg aatcggcaga ataaacagaa tgcttaccac catactgctg
    11881 agacctaata ctgctcccat cagcacgccg gaacaggctt caaagaccgc aatgccagcc
    11941 agcccgccga ttagcatcag caggtaacag ttaaatgcgc cgttgccaaa cagcgtctta
    12001 tagctggcga tcagccgcgt acgcggcgcg ccggcggggc gggtttccgg catccagcgc
    12061 gccatgctga aggtgacgcc agcgcaaagc accagcagga aagcgtaaca cgcgcgccag
    12121 ttccacaggg tatccagcag gccgccaatc agcggcgcta acagcgggct gaccagaatc
    12181 cccatattta acaggctatt ggcatgacga agttgcgttc cttcatacag atcgcgcggg
    12241 agcgttctcg ccattactcc gccaacgccg gttcccatcc cttgcatggc gctggcggca
    12301 atcaacaccg tcaaactatg cgtggtcatg gcgatcagag tcgctaccat aaaaatagac
    12361 atgccgacga ggattaccgg gcggcgccca acccggtcgg aaagcgggcc gtaaaacagt
    12421 tgcgagacgc cgtaggtcag gaggtaagca gccattacgc tctggacggc gccttcccgg
    12481 acgtttagcg cttgtgccat atcggcgatg gcgggaatat aaatggtttg cgccatctgc
    12541 cctacggcca ccagtaacac caacatcaac aacaaattga cgtttctctg ccttttcatt
    12601 tcgctgatta cttttcaaaa aaagaaaaaa taagaataac ttgctgcgca ttcccataaa
    12661 tgcgagagga atctatcaca ccagaaaaag aaggccagac agcaaccagc aatggcagac
    12721 gaaggaacgg caggatatgt aaacaaaagc ggcaacaaat gttgccgaga atgtgttacg
    12781 tctgcagctg ttattgggca atcatgacag acggagtaaa atcgccccga gggcaatccc
    12841 gcccgccgcc accagacgta gcccggccac tttctcttta agcaacagcc aggctatcag
    12901 cgcgccgaat aaaatcgacg tctcacgcag cgcggcgacc accgccagcg gcgcctgggt
    12961 catggcccat agcgccagcc cataagatcc catagtgcca atcccgccaa aaatgccttt
    13021 tttccactgt tgcgccagat aacgcgacgc ttcccgccgc cgcgcaatca tcgcccaagt
    13081 taacaggcag gcgccgttga gaaaaaatga ccatagcgta tagcccagcg ccgtttcgga
    13141 gagtcttacg ccggtcccgt ccaccagcgt atatccggca ataaaacagg cgttagttaa
    13201 tgccagcacg acaccacgtt gagagctggc gcggccatta caggccatcc caagtatcgc
    13261 catgcagatc actgcgatgc cgacctaggc catcgacgac aggctgtcgc caagaaacag
    13321 aacgctaatg agcgccacca gcagcggcgc ggtgccgcgc ataagaggat aggtctggct
    13381 catgtccgag acctgatagg ttttcgccac caggacggta tacaccacct ggagcgcggt
    13441 agaggccgct aaaaaaggga tactggcgtg agctggctgc ggcgagaagg gcaaaaggat
    13501 caatgccatg accgccgcgg aaccgctgac gccgatcgcg gcgtagagct tatcgtttcc
    13561 cgctttgaca atggcgttcc agctggcatg tagcagcgcg gcgaacagca aaatgcagaa
    13621 aacggaaagg gtcatagcat caggcgtcgt tgagggtgtc ataaaaacgt aacatacccg
    13681 ggaagcgaaa gaccagcgga taaggtgaaa ggggagcggt tgcccgctcc ccttcggtgc
    13741 ggcttgaatc tgaattactt aaggtatttc agaacagcat caagcagttg cagtgctgca
    13801 acaatgagtt tcaggataag aatggtgata tccactacgc tcatacgcgt ctcctgtggt
    13861 taaggagcac tgccagccga cgtacctttc cgctgcctgt tgccagctgt tgcgcacgcg
    13921 atcccttttg cgaggaatag tgtgcgtgtt gacataacac agtgtgctca cgagggggtt
    13981 aaggcgctga cggcaccacc cgtttcagcc aggacttcgt tgcgccggtt tacgatgcgg
    14041 cccccgcata acacattgtg tcaaagacat tatagttaag tgctgtataa atgaacagta
    14101 atttatagac agaacggagc ttctgatcca tactcaaatt catcaaaatt cgcgccgaaa
    14161 ttgcgcgttc tgcacagaac gcgtatactt ctgctgttga cataacacag tgtgcttcgc
    14221 ggctaccacc cgcattacgc tgtaagaacc tcgcttcggc gaggtttttt gttttcaggc
    14281 attgtgaaac gcgtgatcat caatcccggc gattaccgga gggcgctacg cttatcacgc
    14341 ctatactcaa agcgtgtaaa ttcgtagaaa aatgtgatcg ctgacgcatt tttgtgcaga
    14401 tgaaaatttt tccgttgtca tgctgaaagc gctgtgcttg tataaaacgt gttaataaca
    14461 aacagacaag gcccctaatg aacccttcca tgctgaacgc gaccctacta acaactgcgc
    14521 catctcgcgc agtggtcgtc gtgcgtgtgg tggtggtcgt cggcaatgcg ccgtagggtc
    14581 cggaacacac acgattccaa aaccccgccg gcgcaaaccg ggcggggttt tttgtttaag
    14641 acaccttccc ggaacgtcgg ctcagaataa aaggaatgga gcatggcaag ttcgggcaca
    14701 acatctacac ctcagcgctt tacgggcgcg gaatttatag ttcattttct ggagcgccag
    14761 gggattcgta tcgtcaccgg cattcccggc ggttcgatcc tccccgttta cgacgcgtta
    14821 agccaaagca cgcaaatccg tcatattctg gcgcgccacg aacaaggcgc ggggtttatt
    14881 gcgcagggga tggcgcggac ggagagtaaa cctgctgttt gtatggcctg tagcgggcca
    14941 ggcgcgacca atctggtcac ggctattgcc gatgcgcgcc tggattccat tccgttaatc
    15001 tgcattaccg ggcaggttcc ggcgtccatg atcggtactg acgcgtttca ggaagtggat
    15061 acctacggta tctctatccc catcaccaag cacaactatc tggtcagaaa tatcaatgag
    15121 ctgcctcagg tgatgagcga tgcttttcgt ctggcgcagt cggggcgtcc tggcccggtg
    15181 tggatagacg ttcctaaaga tgtgcagacg gcgaccattg agctggatgc gttgccgtcg
    15241 ccggcggaaa aatcaccccc gccggagttt agcgcggaga gtatccgcga ggccgccgca
    15301 atgattaacg cggcgaagcg tccggtgctg tatctgggcg gcggcgtgat caatgcgccg
    15361 acacgcgtgc gcgaactggc ggaaaaagcg caactgccga cgacaatgac cttaatggcg
    15421 ctgggaatgc tgcctaaggc gcatccgctg tcgttaggaa tgctgggaat gcacggcgcg
    15481 cgcagtacca attttattct gcaagaggcc gatttactga ttgttctggg cgcgcgtttt
    15541 gatgaccggg cgattggcaa aacggagcag ttttgtccga acgccaaaat catccatgtg
    15601 gatatcgatc gcgccgagtt aggcaaaatt aagcagccgc atgtggctat tcaggcggat
    15661 gtcgatgatg tactggcaca gttaattccc catatcgagg cacagccgcg ggaagcatgg
    15721 catcagttgg tggcggactt gcagcaagaa ttcccttgcg gtattcccca ggaaaataac
    15781 ccgcttagtc actatgggct gattaacgcg gtcgcagcct gtgtggacga caacgcgatt
    15841 attaccactg acgtaggtca gcatcagatg tggaccgcgc aggcttatcc gctcaaccgt
    15901 ccgcgtcagt ggctgacttc cggcgggctg ggcaccatgg ggtttggtct gcccgcggcg
    15961 attggcgcgg cgctggcgaa tccgggcaac aaggtgctgt gtttttccgg cgacggtagt
    16021 ttgatgatga atattcagga gatggctacc gccagcgaaa accagttgga tgtgaaaatc
    16081 atcctgatga ataacgacgc gctgggactg gtgcatcagc aacagagtct gttctataaa
    16141 cagggcgttt ttgcggcaac ctatccggga agcatcaact ttatgcagat tgccgccggg
    16201 tttggtctgg acacctgtga tttgaataac gaagccgatc cacaggcggc gttgcaggct
    16261 atcattcgtc gtcctggacc ggcgttgatc cacgtgcgca ttgatgcaga agaaaaagtg
    16321 tatccgatgg tgccgccggg tgcggcaaat acagagatgg tgggggaata agccatgcag
    16381 aaacaatcac atgataacgt tattctggag ctgaccgttc gcaaccatcc tggcgtgatg
    16441 acccacgtct gcgggctgtt cgcccgacgc gctttcaacg ttgagggtat tctctgttta
    16501 ccgattcagg gtagcgatca gagccgcatc tggcttctgg tcaatgacga tcagcggctt
    16561 gaacagatga taagtcagat cgataaactg gaagacgtgg cgaaggtggt acgaaaccag
    16621 tccgatccca ccatgttcaa taaaattgcc gtcttttttg agtaagttat tcactttccg
    16681 aatcaggcgt gatgactttg acggaaccat tccgacagtg aacggcataa tctgtcggta
    16741 atgggcgatc gctaatcagg acatcaaagg cagaaagcgg accaatgctg gcaggcgcga
    16801 cctcatcaaa cagggcgtga cgcgccagca aaattttgcg cagaccgcgc tccatcgctt
    16861 tacgtttggc ggcaagatca tccgggttaa accagctcac gccaaaatgt tcatgtacgc
    16921 cgctggcgga aataaacact ttgcgcggat taagcgaatc cagcgccgaa ggattattgg
    16981 catcataaaa ggcatcgctc ttggcccgat aggtgccgcc gcacagaatc gctgtggcat
    17041 taggcttttc attcagcgcg ataaataccc gatgcgagta gcaaatcccg gtaaaggtaa
    17101 tatcatccgg tatcatgctg atgactaatg gcatttccgg accgttatca aaaaaaacca
    17161 gatcgttttc acgcaccagg ccggcggcca agatcgcaac gggaaggtcg tcccgatgat
    17221 gcgtcttttt cgccggcagc ggcatattgg ttgaagacgc aggcttattt accatgacga
    17281 tatagccgcc gagcagcgtc agcggtaaag ggtcatcatc ctggctgaga tcgcggcgaa
    17341 tggtcatcac cgaaacttcc agcatccgcg cggcgtcttt cagatggatt cgatcggtct
    17401 ttttcagtaa ctccatcaag cgtcggatac gttctttttg cttggtctcc attcaccctc
    17461 tccgcaaatc atgttgttat gttccatcag taacatttat gtgtttctga gaacattaca
    17521 gtgtggcact actatacgtc tggccgtcag gaaataaaag tgggtttatt cgcgttttat
    17581 aacaataaat agttaatttt cagtaaattg taaccctaaa aatgatttgt tccgccaggg
    17641 gttgttcacg aagtaaatgg caaaatgatc ctctaatcgc gatcatagtc acaaatgata
    17701 cggaagtaac atgataatgt tattttaata tcattgtcgt gtgacgattt ctgagaggga
    17761 gtaaaatgga tatcgcggtt attggctcta acatggtgga ccttatcacc tacaccaacc
    17821 agatgcccaa agaaggggaa actctggaag cgccggcgtt taaaatcggc tgcggcggaa
    17881 aaggggcgaa ccaggccgtg gcggccgcta agctcaattc aaaagtattg atgttgacca
    17941 aagtgggcga cgatattttt gccgacaaca ccattcgtaa tctcgaatcc tgggggatca
    18001 atacgacgta tgtagaaaaa gtaccgtgta ccagcagcgg cgtagcgccg attttcgtca
    18061 acgccaactc cagcaacagc attctgatca tcaaaggcgc taacaagttt ctctcgccgg
    18121 aagatatcga tcgcgcggcg gaagatttaa aaaaatgcca gcttattgtt ctgcaactgg
    18181 aagttcagct tgaaacggtt tatcacgcaa tagaatttgg caagaaacac gggattgaag
    18241 tgttattaaa ccctgcgcca gcattacggg aattagatat gtcttatgcc tgtaaatgcg
    18301 atttctttgt acctaatgaa accgagctgg aaatattaac cggtatgcca gtggatacct
    18361 atgaccatat tcgcgcagcg gcacgttcgc tggtagataa agggctgaac aatattattg
    18421 tcaccatggg cgagaaaggc gcgctgtgga tgacgcgtga ccaggaagtc catgttccgg
    18481 cgtttagagt gaacgctgtt gataccagcg gcgcgggcga tgcctttatc ggctgtttcg
    18541 cgcattacta cgtccagagc ggggatgtgg aagccgccat gaaaaaagcc gtcctctttg
    18601 ccgctttcag cgtcaccggg aaaggcaccc aatcctctta tccaagcatt gagcaattta
    18661 atgagtatct ttcattgaac gaataacaat caccctgcac tgttaaaggt agcactatga
    18721 acgataaaaa catcgttcag atgcccgacg ggtatctgaa taagacacct ctgttccagt
    18781 ttattttgtt atcctgttta ttcccgttat ggggatgcgc agccgcgtta aatgatattc
    18841 tgattacgca atttaaaagt gtattttcgc tgagcaactt tgcttcggca ttagtacaaa
    18901 gcgcctttta tggcggttat tttttaattg ctattccggc ctcgctggtc attaaaaaaa
    18961 ccagttataa agtggcgata cttatcggcc tgacgctata cattgtcggc tgtacgctct
    19021 tttttccggc gtcgcacatg gcgacctaca ccatgttcct cgcggcgatt ttcgccattg
    19081 cgattggcct gagtttcctg gaaacggcgg cgaataccta cagttcgatg atcgggccga
    19141 aagcctacgc cacgctgcgg ctgaatatca gccagacctt ttatccgatc ggcgcggcgg
    19201 caggcatttt attgggtaag tatctggtct tttccgaagg ggaaagcctg gaaaaacaga
    19261 tggcgggcat gaatgccgag caagtccaca acttcaaggt gttgatgctg gaaaacactc
    19321 tggaacccta taagtacatg attatggttc tggtagtggt gatggtactg ttcctgctga
    19381 cgcgttttcc gacctgtaaa gttgcgcaaa ccgcgagtca taaacgtccc tcggcgctgg
    19441 atacgctacg ctatctcgcc agtaacgccc gcttccgtcg cggtattgtg gcgcagttcc
    19501 tgtatgtggg aatgcaggtg gcggtctggt cgttcactat tcgtctggcg ctggagttag
    19561 gcgatatcaa tgagcgcgat gcctcaacct ttatggtcta cagcttcgcc tgctttttta
    19621 tcggcaagtt tatcgccaac attctgatga cgcgcttcaa cccggaaaaa gtcctgatcc
    19681 tttactctgt gatcggcgcg ctgttcctgg cctatgtggc gctggcgccc agctttagcg
    19741 cggtatacgt ggcggtgctg gtcagtgttc tgtttggccc ctgctgggcg accatttatg
    19801 ccggaacgct cgataccgtc gataacgagc ataccgaaat ggcgggggcg gtcatcgtga
    19861 tggcgattgt cggcgcggcg gtggttcccg cgattcaggg ctacgtggcg gacatgttcc
    19921 actcgttaca gctctcattc ctggtttcca tgctgtgctt tgtttacgtt ggcgtttact
    19981 tctggcgcga aagcaaagtg cgcggcaacc tggctgaagt cgccgcgtcc tgaggagatc
    20041 aaccatgaca acacgtatta cattatggcg ggagcttttt agcgagcagc cgcgtatctt
    20101 gctggaaaat gacgatttta cggttacggc gtttcgttac gccagcggcg tggaaggact
    20161 gaaaatacaa aacagccgcg gtcatctggt gattctgccc tggatggggc agatgatttg
    20221 ggacgtgcag tttgacggtc atgatctgac tatgcgcaac atgttccgcc agccgaagcc
    20281 ggctgcggaa gtggtggcaa cgtatggttg ctttgctttc cattccggac tattggcgaa
    20341 tggctgcccg tcgccggaag atacacatcc gctgcacggc gagatgccct gcgctgctat
    20401 ggacgacgcc tggctggagt tagagggcga cagtctgcgc gtgaccgggc gctacgagta
    20461 tgtgatgggg ttcggtcatc attatcaggc gcaacctgcg gtggtaatgc gtaaatcaag
    20521 cgcgctgttt gatattcaga tgaccgtgac taacctggct tcagtcgcca tgccgctaca
    20581 gtacatgtgc cacatgaact atgcctatgt gccgaacgcc acgttccgcc agaatatccc
    20641 ggataccgcg ctgaagctac gcgagtcggt gccagcgcat gtcaaaccca cggcgcagtg
    20701 gctggcgttt aatcaacgac ttttgcaggg tgaagcctcg ctggcaacgc tcaacgagcc
    20761 tggcttttac gacccggaaa tcgtgttctt cgccgatgaa ctggacaagt acacggatac
    20821 cccggaattc agtatgatcg ccccggatgg caccacgttc gtgacacgtt tcgccagcgc
    20881 ggagctgaat tacgtgaccc gctggattct ttataacggc gatcagcagg ttgccgcctt
    20941 tgccctgccc gcgacctgtc ggcctgaagg ttttctcgcg gcgcagcgaa atggaacctt
    21001 gcttcaactg gaaccgcagc aaacccggac gttcaccgtc acgacaggca ttgtctgacc
    21061 gctcaaggct tgaacaccca ggcacttatc gttaaggtaa gtgcttttgc cggatggcgg
    21121 cattaatgcc ttatccggcc tacaacggca cctgcccgta ggcctgataa gcgcagcgcc
    21181 atcaggcatg tcttagcgcc aggatgaacc catgattacc gttgccctta tcgacgacca
    21241 ccttatcgtc cgctccggct ttgcacagct actggggctg gaacccgatt tgcaggtggt
    21301 cgccgagttt ggttccgggc gcgaagcgtt ggcaggcttg ccggggcgcg gcgtacaggt
    21361 gtgtatctgc gatatctcga tgccggatat ttccggactg gagctgctaa gccaactgcc
    21421 aaaagggatg gcgacgatca tgctctcggt tcacgatagc ccggcgctgg tggaacaggc
    21481 gttgaacgcc ggcgcgcgcg gttttctctc taaacgctgt agtccggatg agctgatcgc
    21541 cgcggtgcat acggtggcga cgggcggctg ctatttgacc cccgatattg ccgtgaaact
    21601 ggcggcgggt cggcaagatc cgctgaccaa acgcgagcgt caggtggagg aaaaactcgc
    21661 ccagggtatg gcggtaaaag agattgccgc cgagctgggg ctgtcgccaa aaatggtgca
    21721 tgtccatcgc gcgaatctgc tggaaaaatt aggcgtcagc aatgacgttg aactggcgca
    21781 tcgcatgttt gacggttggt aatgaacacc tttttttccc gtttaatcac cgttgttgcc
    21841 tgctttttta tcttctccgc cgcgtggttc tgcctgtgga gcatcagcct gcatctggta
    21901 gagcgcccgg agctggcggc gctactcttt cccttcggcc tgcgcctggg acttatgctg
    21961 caatgcccgc gcggatactg gccagtattg ctgggcgcgg agtggctgct ggtgtactgg
    22021 ttggcgcagg aagttgcgct ggcccatctg ccgcttttga tgatcggtgg tgtgttgacg
    22081 ctactgcccg tggcgctgac ttctcgttac cgccatcagc gcgactggcg cacgttattg
    22141 cttcagggcg cggccctcac cgccgcggcg ctactgcaat ccctgccctg gctggggcag
    22201 ggggaagcgg catggaacgc gctactgctg accctcacgg ggggactgac gctggccccc
    22261 atctgcctgg ttttctggca ctatctcacc agcactacct ggctgccgct gggaccatcg
    22321 ctggtatcgc agccggtaaa ctggcgcggg cggcatctga tctggtatct gctgctgttt
    22381 atcgtcagtc tgtggctgca actggggtta cctgctgaac tttcgcgctt cacgccgttc
    22441 tgcctggcgt tgccgattat cgcgctcgcc tggcattatg gctggcaggg cgcgctcatt
    22501 gccacactga tgaacgctat cgcgctgatc gccagccaga cctggcacga tcatcccgtc
    22561 gatttattac tttcgctgtt ggcgcaaagc ctgaccgggc tactgcttgg cgcgggcatt
    22621 cagcgcctgc gcgagctgaa ccagtcgctg caaaaggagc tggcgcgcaa ccatcggctg
    22681 gcggagcgtc ttctggagac cgaagagagc gtacggcgcg atgttgcgcg tgagctgcac
    22741 gatgacatcg gacagaccat caccgcgatt cgaaccctgg cgggcattgt gcaacgactg
    22801 gcggcggata acggcggcgt gaagcagagc gggcaactta tcgagcagct ttcgctgggc
    22861 gtgtatgacg ccgtgcgtcg cctgctgggg cgcttgcgcc cgcgccagct agacgactta
    22921 acgctggcgc aggccatccg ttcgctgctg cgcgaaatgg agctggaaag ccgcggtatt
    22981 gtcagtcacc tcgactggcg aattgacgaa acggcgctaa gtgaaagtca gcgcgtgacg
    23041 ctgtttcgcg tctgtcagga agggctgaat aacatcgtaa aacatgccaa tgccagcgcg
    23101 gtgacgctcc agggctggca gcaggatgag cggctgatgc tggtgattga ggatgacggc
    23161 agcggcctgc cgccgggctc tcaccagcag ggcttcggcc tgaccggaat gcgcgaacgc
    23221 gtgtcggcgc tcggcgggac gctaaccatc tcttgtaccc acggtacgcg ggtgagcgtc
    23281 tcgttgcccc agcgttacgt ttaaggaagg ataatgcttt cgtttttaaa agccccggcc
    23341 aacgcgccgc tcatcaccga taagcacgag gttgacgccc gctatcgcta ctggcggcgg
    23401 tatatcctga tcaccatttg gttgggttac gcgctgttct atttcacccg taaaagcttt
    23461 aacgccgccg cgccggaaat ccttgccagc ggtattctga cccgcagcga tatcggcctg
    23521 ctggcgacgc tgttttacat cacctacggg gtgtcgaaat ttgtctccgg catcgttagc
    23581 gatcgctcta acgctcgcta ttttatgggc atcgggctga ttgcgaccgg cgtagtgaat
    23641 attctgttcg gcttctcgac ctcgctgtgg gcctttgcgc tgctatgggc gctgaacgcc
    23701 tttttccagg ggtttggatc gccggtttgc gcccgtttgc tgactgcctg gtactcgcgt
    23761 accgagcgcg gcggctggtg ggcgttatgg aacaccgcgc ataatgtcgg cggggcgctg
    23821 atccctctcg ttatggccgc tgtcgccctg cattatggct ggcgcgtcgg gatgatggtg
    23881 gccggattgc ttgccatcgg ggtgggcatg gtcctctgct ggcggctgcg cgaccgtccg
    23941 caggcgattg gtttaccgcc ggtaggcgac tggcggcacg atgcgctgga ggtcgcccaa
    24001 cagcaagagg gcgcgggact aagccgcaaa gaaatcctcg ctaaatatgt gctgtcgaat
    24061 ccctatatct ggctgctttc gttgtgttat gtcttagtgt acgtggtgcg cgcggcgatc
    24121 aacgactggg gcaacctgta tatgtccgag acgctgggcg tggatttggt cacggccaac
    24181 acggcagtat cgatgtttga gttgggtgga tttatcggcg cgctggtggc gggttggggc
    24241 tcggacaaac tcttcaacgg caaccgcgga ccgatgaatt taatcttcgc tgccgggatt
    24301 ttgctctctg tgggttcgct gtggctgatg ccgttcgcca gctacgtcat gcaggcggcc
    24361 tgtttcttca ccaccggttt ctttgtcttc ggcccgcaga tgctcattgg catggcggcg
    24421 gcggagtgct cgcataaaga ggcggcgggc gcagccaccg gctttgtcgg cctgttcgcc
    24481 tatctcggcg cgtcgctttc cggctggccg ttagcgaaag tgctggagat ctggcactgg
    24541 accggttttt ttgcggtcat cgccatcgcg gcggggatct ccgcgctatt gctgctgcca
    24601 tttctgaacg cccaggcccc acgcgagacc cacgaagcgt gatacacctc acctttttgc
    24661 gctgaatggg gcaaaactaa gaaattttcc cggttttgcc tggacgctgt cgcaggcccc
    24721 ttttcctgtg gatttttaca atgcctgcca ttcgcaggta taaaaattag ctcaggagta
    24781 atccatgctg gccttcttaa accaggtgcg caagccgacc ctggatctgc cgctcaatgt
    24841 gcggcgtaaa atgtggttca agtcgttcat gcagtcctat ctggtggttt ttatcggcta
    24901 cctgaccatg tacctgatcc gcaaaaactt taacatcgcg cagaacgaca tgatctctac
    24961 ctacaggttg agcatgaccg agctggggat gattggcctg ggcttctcga tcacctacgg
    25021 cgtggggaaa acgctggttt cctactacgc tgacggtaaa aataccaagc agtttctacc
    25081 gtttatgttg atcctctccg ctatctgtat gctcggcttc agcgccagca tgggcgcggg
    25141 gtcaaccagt ctgtttctga tgatcgcttt ctatgccctg agcggtttct tccagagtac
    25201 cggcggatcg tgcagctact cgaccatcac caaatggact ccgcgtcgta aacgcggcac
    25261 ctttctcggc ttctggaata tctcccacaa cctcggcggc gcgggcgcgg caggcgtggc
    25321 gctgttcggc gccaactacc tgttcgacgg tcacgtcatc ggcatgttta tcttcccgtc
    25381 gattatcgcg ctgattgttg gctttatcgg tctgcgtttc ggcagcgact ccccggaatc
    25441 ttacggtctg ggtaaagctg aagaactgtt cggcgaagag atcagcgaag aggataaaga
    25501 gactgaagaa aacgaaatga ccaagtggca gatctttgtt gaatatgtgt tgaaaaacaa
    25561 agtgatctgg ctgctgtgtt tctccaatat cttcctgtat gtggtgcgta ttggtatcga
    25621 ccagtggtca accgtctacg ccttccagga actgaaactt tctaaagagg tggcgattca
    25681 gggctttacc ttgtttgaag tgggcgcgct ggtcggcacg ttgctgtggg gctggctctc
    25741 tgacctggcg aacggtcgtc gcgcgctggt agcctgtgtg gcgctggcgt tgatcatcgc
    25801 taccctcggc gtctaccagc acgccagcaa ccagtatgtc tatctggcct cgctgttcgc
    25861 gctcggtttc ctggtgtttg ggccgcagct attaattggt gtggcggctg tcggtttcgt
    25921 accgaaaaaa gccatcggcg ctgcggacgg tatcaagggc accttcgatt atcttatcgg
    25981 cgatagcttt gctaagctgg gtctgggcat gattgccgac ggcacccccg tttttggtct
    26041 gaccggttgg gcgggtacct tcgccgcgct ggacgctgcc gcgatcggct gtatctgcct
    26101 gatggcgatg gtcgccgtga tggaagagcg caaaatccgc cgtgagaaaa aaattcagca
    26161 agtcaatatc gcttaaatgt gtgcatttgg taacgttttg cccggcttaa cgccgggctt
    26221 ttttatgcct tgcgttcgtc agacaggaca tccggtgtct ggcgtaaatg aagacaggcg
    26281 ttaataaatc acatcctgac aggccagaac gtcgacagtt ataaatttac cgttatgatg
    26341 ggcatcctgt ttggtgacgg atgtgcgcat gatttggttg attctggcca cgtttgtggt
    26401 ggtgtttatt gtgggttttc gggtgctgac atcggatacc cgccgggcga ttcgccgtct
    26461 gagcgaacgt ctgaatattg atgtagtgcc gatagaatcg atgattgatc agatgggtaa
    26521 aacggcgggc ggtgagtttt tacagtatct gcatcgccct gatgaatcgc atttgcaaaa
    26581 tgccgctcag gtgttactga tctggcaaat ggtgattgtc gatggcggcg atcagaattt
    26641 gcagcggtgg catcgcttgc tgcaaaaagc gcgtttagcc gcgccgatca ccgacacaca
    26701 ggtacggctg gcgctgggct ttttgcgcga aatggaaccc gatatgcagg agatcaacgc
    26761 gtttcaactg cgctataacg ccttttttca gccggaagag ggtgtccact ggctgcattg
    26821 atactcttca ctatctcgtt aacaaaagac gagatgaatg aggctggcaa gggcggcgag
    26881 ccacgattaa cggccggatg gcacgattca tcgttagcca aataaagcgt agccgccatc
    26941 gtatttgcta agggtgaacc acagaagtaa cgcaccgaat aaccgctaac gacgccaaaa
    27001 catcagagac ttatagctca tcatttctgt gacatatatc acggaaatgt gatcttgttt
    27061 tgaacaccaa aactgtgact ccttgccata cctcctgtct caaaatttct tatcataaac
    27121 tcgaagttgt acatgattgt ctatagacaa ctctaaatgt ttaggcgcgc actatgaaaa
    27181 cattgagtaa aagttcacac atcccactgt atcaacaggt tgtggagtgg ataagggaaa
    27241 gtatttatag cggagaattg gttgaggatg accggatacc ttcagagttt caaatcatgg
    27301 atatgctgga ggtgagtcgc ggtaccgtta aaaaagcggt tgaccaactt gtccgggaag
    27361 gtgttcttgt gcaagtgcag ggtaaaggaa ctttcgtaaa gaaggaaaat gttgcttacc
    27421 cactgggtga aggtttgctc tcctttgctg aagccttagc cagccagaag ataaacttca
    27481 caaccagcgt cataacctcc cgactggaac ccgctaaccg ctttgtagca gagaaactga
    27541 gtatcaaacc gggacaagat gttttatttc ttaaacgcct tcgttgtatt ggcgatgaaa
    27601 aagtcatgtt gattgaaaat cgtatcaaca ttgatctctg ccccggtatt attgatgtag
    27661 attttactag ggagaattta ttttcagcaa tagaaagatt atctgataag aaaataagtt
    27721 tttctgaaag ccgttacgca gctaaattaa ttggtaatga gcgaggccat tatcttgata
    27781 ttggtgaaga cgcacctgtt ttgcatttgg aacagttggt atttttctct agaggattgg
    27841 ccattgattt tggtaacgtc tggttaaaag gtaataaata ttatcttggc actattttac
    27901 agcgcctgga tgcctgacta gcaaagagga atctatgcag gatattcatt ttcgccgtca
    27961 ttatgttcgc cacctcccta aagaggtgag tcagaatgac ataatcaagg ctcttgccag
    28021 tccgttaatt aacgatggta tggttgtatc tgattttgcc gatcacgtca ttacgcgaga
    28081 acagaatttt ccaacgggtc taccggttga gcctgtaggt gtcgctattc cacatactga
    28141 tcacaggtat gttcgccaaa acgccattag cgttggaata ctggcagaac ccgtcaattt
    28201 cgaagatatg ggcggggaac cagatcccgt acctgtcagg gtggtgttta tgcttgcttt
    28261 aggtgaaagc aataagcagc tcaacgtact gggttggatt atggatgtga tctaggatga
    28321 ggattttatg cagcagttac tggtcatgaa tgatgatgaa atttatcagt caatttacac
    28381 acgcatatct gaaagaggtg aagtatgagt aaaatgatac tatttgtttg cgcaacgggt
    28441 gttgctactt ccacggctgt ggcagaaaaa gtaatggaat attgtaaaga caatgggctt
    28501 gatgttaatt attcccaaac taatgtagcc tcattgccaa acaataccga tggtgcagct
    28561 ttggttgtat caacaacgaa agttccttat gaactggata ttccggttgt tagtggtctg
    28621 ccaatcatta ccggagtagg tgaagataaa gttcttgaaa aaatagtttc aatccttaaa
    28681 ggccaagcct gatttcataa ataaaaaaca gataaattac ccaggcgcta acgcgaggtc
    28741 tggtcacatc tgaataagag gtcggatatg aatgatatag cacatactct ctataccgtt
    28801 gtgcaatatg tcctgggatt tggcccaacg gttttattgc cgctggtcct ttttttcctg
    28861 gcattgttct tcaaagtaaa acccgctaaa gcacttcgct catcgttaat tgtcggaata
    28921 gggtttgtcg gaatttatgc catctttgac atacttacca gcaacgtagg cccggctgca
    28981 caggcaatgg ttgagcgaac tggtattagt cttcctgttg tcgatttagg ctggccacca
    29041 ttggccgcaa ttacctgggg ctcaccaatc gccccctttg tcattccgct gacgatgctg
    29101 attaatgtcg ccatgctggc cctgaataag acacgtactg ttgatgtcga catgtggaac
    29161 tactggcact ttgccctggc gggaacgctg gtttactaca gcacagggag ttttgttttg
    29221 ggtctgtccg cagccgctat tgccgcgatc gtggttctca aactggcgga ctggtcagcg
    29281 ccattagtgg caaagtactt cggtctggaa ggtatttcac ttccgaccct gtcatctgtc
    29341 gtcttctttc caattggatt gctgttcgac aaaattatcg acaagatccc gggtgttaac
    29401 cgtattcata ttgatccgga aaacgttcag aaaaaaatgg gaatcttcgg cgagcctatg
    29461 atggtgggta ctattctggg ggtcttgttg ggcatcattg ccgggtatga ctttaaacat
    29521 atcctgttgc tggggatcag cattggcggt gtcatgttca ttcttccgcg tatggtacga
    29581 attttgatgg aaggtttatt acctctgtct gaagccatta agaaatattt gaatgccaaa
    29641 tatcctggcc gtgatgatct ctttatcgga ctggatatcg cggtagcagt aggtaaccca
    29701 gccattatct ctacagcact gattctgaca cccatctctg tcttcattgc attccttctt
    29761 cctggcaata aagtcctgcc actcggagac cttgcgaacc tggcagtcat ggcttccatg
    29821 attgtactgg catgtcgtgg caatattttc cgggctgtga taaccgcaat tcctgttatt
    29881 atcgccgact tgtggattgc gaccaaaatt gcgccattta ttaccggtat ggctaaagat
    29941 gtcaatttca aaatggctga ggggtcaagt ggtcaggtat caagcttcct tgatggcggt
    30001 aaccccttcc gtttctggct gcttgaaatt ttcaacggaa atattattgc tatcgggctg
    30061 attcctgtgc ttgcgctggt tatttatggt gtttttcgcc tgacaaaagg aacggtctat
    30121 gcctgattac cacgcagcgc ttgtcattga cattggtaca actaactgca aagtcagctg
    30181 ctattcctgt catgacgtgt cagttctgga agtccgcaag tttccgacgc caacaatatc
    30241 gtcggacaaa ggcgaggtag atttagatat cgaagcgctg tggcaggcac tgcgactggt
    30301 aatggctgaa ctggtggctt cagtaccgtt tccggtaaaa aatatcagta ttgcgagttt
    30361 cggtgagtct ggcgtctttg tggataagga gggcgtcatt cttaccccga tgctggcctg
    30421 gtatgatcga cgtggtgaat cttatctctc gtcattaagc aaggcagagg ctgaagaact
    30481 gtattctata acgggattgc cacctcacag taattactca gcatttaaaa tgagatggtt
    30541 gcttgataac tactccttgc atgaaagaaa agatatctgc tggttacatg ctccagaagt
    30601 gttgttgtgg cgaatgacag gtgcgaaaaa gacggaaata tccctggcca gtagaacgtt
    30661 gtgtctggac attgctcgcc gtacctggtc tcgtaatgct gccgggattc tcggcatacc
    30721 gttcggtgta ctggctccgt tgataaagcc gggtgaagtg gctggatggg tgacggcaac
    30781 gctcaggcag gagttgggat taccacatga ggtaaaagtt accctggccg gacacgatca
    30841 tatggtcggt gcccgcgcat tacagatgca accgggcgat gtgctgaatt ctaccggcac
    30901 gacagagggt attttactgc tgaatacaca gccaacgctt gatgtgcagg ctcgcaggga
    30961 taagctggca aatggttgtt actccgatgg tgaatttttc acgcttttcg cttctctgcc
    31021 tgtcggcggt tatgcgcttg aatgggtgaa aaaaaccttt cgtttaactg ataaggaaat
    31081 aagcacaggc ctggaaaaag tcatggagca atacctcaaa ccttcctggt ctgtcgagca
    31141 tgtgccggta tttattcctc atttgcgggg ctcgggttcg ccacataaaa accagcacac
    31201 tcgtggcctg ctttttggtc tgacggattc acttcctccg gagtctctgc ttgagagtgt
    31261 ctttatcggc ctggcgatgg agtttgcaca ctgtcacggg tgctttaata tcccggcagg
    31321 caggacagta aaagtcattg gccctgcggt gaaaaaccca tactggctcc agttgaaggc
    31381 tgacatcctc cagtgtccaa ttgaggccat tgcttttgat gaaaccgtct cccttggagc
    31441 attgttgata gcctgtccga atgttgtccc cccgactgtt cctgtggctg agcgatattt
    31501 tcctgacgcg gttcgttctg caaagttgaa aatatatcag cagcaatggc tgtcatttta
    31561 ccaatttaaa ctgcggcaag aaggggcgtt tattggtgaa taactgtgat aactcaatag
    31621 ttcgataatt tacttatact gctcacataa atatctggag ttaatatgtc tttagtcaat
    31681 ggtaggatcc tgctcaattg tattcaggaa aaacatgtcc ttgcgggggc atttaataca
    31741 acgaacctgg agacaacaat ttccattctt aatgcaatag aacgttccgg attgcccaat
    31801 tttattcaaa ttgctcctac taatgcacag ctttcaggtt acgattacat ttatgaaata
    31861 gtgaagtgac atgccgataa aatggatatt cctgtcagcc tgcatctgga tcatgggaaa
    31921 actctggaag atgttaagca ggctgtccgg gccggattta cctcagtaat gattgatggc
    31981 gcggcgctac cgttcgaaga aaatattgca tttacccgag aagctgtcga tttctgtaaa
    32041 tcatttggtg ttcccgtcga agcggaatta ggcgctattc tgggtaagga agatgatcat
    32101 gtcagcgagg ctgactgcaa aactgaacct gagaaggttc agcgctttgt tgaggagaca
    32161 gggtgcgaca tgctggcagt gtcaattggt aatgtacatg gtcttgaaga catcccacgc
    32221 attgatatcc cgctattaca acgcatcgcg tctgtcagtc cggtaccttt ggttattcat
    32281 ggaggttctg gtattgacgc ggatattctt cgcagctttg ttaattacaa agtagccaaa
    32341 gtgaatattg cgagtgattt gcgcaaagcc tttattacta ctgttggtaa ggcttgggta
    32401 aataataaca acgaggctaa tctggcgcgt gtcatggcga gcgcaaaaca ggcagttgag
    32461 gatgatgttt attctaaaat taagatgatg aataaacatc actcagcact ccgcaaagtc
    32521 tcttaaggaa aatatatgat tagacaaaaa gtacgcgtta tgaacagtac ggggcttcat
    32581 gcgcggccag ccgctacact tgcgaaaatt gtcaaaaaat accagtcttc attaacgcta
    32641 gttaataatg acaaagaaat tcccattaaa ggaatgatga gtattttggg ggctggcgta
    32701 aagggaaaca caatgattga tttaatttgt gatggacagg atgaactggc ttttatggat
    32761 gaattaaaat ccgcatttgc tgatggcttt ggtgagtcag tatagtgcaa ttcccgtcaa
    32821 acggcgcagg aagttgtaga ggcttcctgc actcattatc gtatgaatag ccttaacaga
    32881 ccatcggtaa aaccctcata ccagcacctt tagcccgtgt ttttggacaa cattaagtag
    32941 tttcagtgac atcccgctgg gacgcttggc gccgctttcc cacttttgaa ccgttgatac
    33001 gctggtattc aggtaccgag cgaaaaccga ctggctaacg ttgagttctt ctcgtaacgc
    33061 ttttatttca agtggctgca ggtctttgat gctgcttaag caggccgtgt caaaactgcg
    33121 cattgtctcc tggggaatgg catccacgct aaataatcca gatgccgcgc tatgaatcgc
    33181 ttcaaaggca gggcttttga atttagtttt tgctgacatg gcgcacctct accagttctt
    33241 tgttattaat gagtgccgtt atctgatctt cggtcaggca agcatagtgt tttgctaact
    33301 cacggaaacc cgcaagttcg cgatagcgaa tgttggccat attctgtttg gtatacagga
    33361 aggtgtaaaa ccaatgttcg cctccctttg ccaacacgat tgcgcgatcg cggttttaat
    33421 tgagacgttt ttataaactc cgccgccaag attatctgct tttccttgca gtacggcgtt
    33481 gatggcctcg cttaactcgt catcttttat cgtgtgggac ttcgcttctc tgttaaacca
    33541 cctggttttg aagattcgca tcaggttgac atcctgtaat ctaaagtata gcaccaggtg
    33601 atacactatg tcttaccttt tggttttaca cgcagcgaga gaagataatt ctcaacgctc
    33661 gaccagcctc gcaaaatgca gcgcaacaat gtcagttgct aaaacgttaa tcagatcaca
    33721 ttttgtaatg ttacactgcg tggattttcc gcactaaaac gacgcaggta accacaatga
    33781 atgaaaatat cgcagaaaaa ttccgcgctg atggggttgc caggcctaac tggtcagccg
    33841 tttttgccgt ggcgttttgt gtcgcctgcc tgattaccgt tgagtttttg cccgttagtc
    33901 tgttgacgcc gatggcgcag gatctgggga tctccgaggg cgtcgccggt cagtcggtca
    33961 ccgttacggc gtttgtcgcg atgttttcca gcctgttcat tacccagatt attcaggcga
    34021 ccgacaggcg ttatatcgtt attctgttcg ccgttttgct gacggcttct tgtctgatgg
    34081 tctcctttgc caacagcttt acgctgctat tgctgggccg cgcctgtctt gggttggcgc
    34141 tgggcggatt ctgggcgatg tcggcgtcgc tgaccatgcg actggttccc gcgcgtaccg
    34201 tgccgaaagc gctgtcggtg atttttggcg cggtctccat cgcgttagtg atcgccgcgc
    34261 cgctgggcag ttttttgggc ggtattattg gctggcgtaa tgtctttaac gccgctgcgg
    34321 tgatgggcgt actgtgcgtc atctgggtgg tgaaatcact gccgtcgctg ccgggcgaac
    34381 cttctcacca gaaacagaat atgtttagcc tgttgcaacg ccctggcgtg atggccggga
    34441 tgatcgccat ctttatgtct tttgccgggc agttcgcttt ctttacctat attcgcccgg
    34501 tctatatgaa tctggcgggc tttgacgttg atggtctgac gctggtgctg ctaagttttg
    34561 gtattgccag cttcgttggc acttctttct cctcttacgt cctgaaacgt tcggtaaaac
    34621 tggcgctggc cggtgcgccg ctgctactgg cgctgagcgc gctgacgctc attgtgtggg
    34681 gaagcgacaa aaccgtggcg gcggcaatag cgattatctg gggactggcg tttgcgttgg
    34741 tgccggtggg atggtcaacg tggatcactc gttctcttgc cgatcaggcg gaaaaagccg
    34801 gttccatcca ggtcgcggtg attcaactgg caaatacctg tggcgcggcg gtgggcggtt
    34861 atgcgctcga caatttcggg ctgctttcgc cgctggcgct ttccggcggt ctgatgctgt
    34921 tgacggcgtt agtcgtggcg gcgaaagtcc gtattacgcc aatgagttga tattgctgcc
    34981 atttgtaggc cggatacgac gttagtcgtt atccggcaat aataaacgct taatcaaaac
    35041 cgttatgctc tgcggtggcg gcaaaccatt ctccgctttt tttcaccgtg cgcgtttggg
    35101 tggctaaatc cagttgtaca aaaccatagc gatttttata gccgttcagc catgaccagt
    35161 tatcgataaa ggtccacatg tggtagccaa gacagtgaca gccctcgcta atgcctttat
    35221 gcagccattt aagatgctca gagataaagt caatccggta atcatcgtga atctgtcccg
    35281 cttgcacaaa acgctgctcg ttctcaacgc ccatcccgtt ttcggagata aaacagcgcg
    35341 gattgccgta attatcccgc aggttggtga tgatgtcgta aattcctggc gcgtaaattt
    35401 cccagccgcg gtaagggttc atcttgcgcc ccggcatgtc gtaatagtca aataaccact
    35461 ccggcataaa cggcgcttgc ggattcaccg ctgtatcacg gcatttcacg cggcgcggct
    35521 gataatagtt aatccccagt aaatcgattt tgccgtcggc aataagctga cggtcgcctg
    35581 gctgacaggc aggcagctgg tcataggttt tcagcagcgc caccagctcc gccgggtatt
    35641 ctccctttaa taccgggtca agaaaactgc ggttgaataa cagatccgca tgatgcgcgg
    35701 cttgcacatc ggcgggatgc tgcgagcgtg ggtaggacgg cgtcagattc agcactacgc
    35761 cgatttcacc gtcgtagcgc ccggcgcgcc aggcgcgcac ggcggtcgag tgcgccagca
    35821 cggtatggta cgccacggtg gccgcacgtt taaaatccac cacattggga tagtggaagt
    35881 cgtacaaata gccgccttcc accggcacaa tcggctcgtt aaaggtaaac cagtgcttca
    35941 cgcggtcgcc aaacaaggta aaacacgttt gcgcgtaccg accaaacgcc tctacgacgt
    36001 cgcgattttc ccagccgcct ttctcctgca tgaccatcgg catatcaaaa tggaacagcg
    36061 taataaacgg cgtgatgccc tgcgccagta gctcgtcgat gacgtgattg tagaagctca
    36121 ccgcttgtgg attcacctcg cctacaccgt ctggaatgag ccgcgcccag cttagcgagg
    36181 tgcgaaaact gttgtgtttt aactgtttca gtagcgcgat gtcttgcttc cagtggcgat
    36241 agaacgttga ggtttccgct ggaccgatgc cctgatgaaa acgatcaggc tggcgctcga
    36301 accacacatc ccacgtggtc tggcttttac caccattcag actatcccct tcggtttgca
    36361 acgctgagca ggcgctgccc caccagaagt tatcgggaaa acggtatcgc attgtcgtac
    36421 tccttgatcg cgtaaattcg ctccagaata tgcgcttttg gcgaacagaa accggttaca
    36481 gtccgcattt tcgcgaccaa aaagcggaaa agctgtgcta catctccggg cattccacct
    36541 tgccgagagc ctgccagtag ttatgctgat tgttgcgctc tatcgcgatc atcgcctccc
    36601 gaatatgctg ctggttcccc tcgcttgtca tgattttttt ctcccaggct tcatcggtta
    36661 gcgcgccttt gggcgtacac attttgcgca aatcctttaa aatcgtattt ttttcatgcg
    36721 ccgactggag tgagctaaac ggagagtcgg catacgtgac gcccggtagc gcgacaagtg
    36781 tggcaataag cagaagcgtt tttcgtttca taaacggtat ccttatcggt ttgcactttt
    36841 tcaagagtaa gtgtagaccg tgcgacgttc actcatcggg gcgtgctatc cgttggcgtt
    36901 gaagtcaggc aaaagtggga aggcggtttc tcgctgcgcc ttcactttct tgcgtggcag
    36961 aatagtgtat gttctgacta ctcttttatt tcgtaagcgg tagtgtaatg agacgtattg
    37021 agatcgtact gggagagctg gaacggctga cgcgcgggct atgccttgcc gatttggcgc
    37081 aggagacggc gtttacggcg gaggcgatag gtttcaatct tgggctggcg cgtaactccg
    37141 tcagcaaaga tctcaatcag ttatggaatg acggcctggc aatcaaaagc cgtggccgcc
    37201 cggtctattt tttggcatcg ccaggcgctg gaaacgttgc tgggacgtca gctggaagag
    37261 tctgaacgcg aggtgcggtc ggtggcggat gtgctgccgc atgaagagca ttacgcgccc
    37321 gacgatccgt ttaccagcct gattggttac gatcgcagcc tgcgcgatgc ggtagaaaaa
    37381 ggccgtgcgg cggtgctcta tccgcacggt ttacacgttc tgcttaccgg gccgtccggc
    37441 gtcggtaaaa ccttttttgc ggaactgatg caccgtttcg cctgtgaaca ggcgagcggc
    37501 gctatcccgc cgctggtcta ctttaactgc gcggaatacg cccataaccc ggaactgctc
    37561 tcctcgcatc tgtttggtca tcggcagggg gcgtttaccg gcgcgaatga acataaaaca
    37621 ggcctcgtgg agcaggcgga cggtggttat ctgttgctgg acgaggtgca ccgtctgtct
    37681 tatgaagggc aggaaaagct gttttctatt ctggataaag gcgagtaccg tccgctcggc
    37741 gtgagcagcc agccgcgatc aatttcggta cgcctgattt gcgccactac cgaaccggtc
    37801 gggtcggcgc tgttacgtac tttccagcgg cgtattcagg tatgcattga tttgccgggc
    37861 attcgccagc gctccgttga agaacagatc gaactgatcg tggggttctt acagcgggaa
    37921 agccgcaaaa tagaacgcac ggtcagcatt gataaaccgt tgttgctctg gttgctgaat
    37981 aaacccctgg aaggcaatat cggtcagcta aaaagcgata ttcagtttct ttgcgctcag
    38041 gcgtgggcat cgggaatgac cgagcataac gacacgctac agctggataa acggctggcg
    38101 gagatgtcgg ttaacccgac gccggaacag cgtctattgg tggatactct gtttgacggt
    38161 aaagcgcggc taaatataga cgcgcgcacg ctgcccgcat tgaagacgtc gctggcgacc
    38221 ggggcggaaa ttgaagagag cgacctcttt tacagcttcc tgacgcgcga gtatgttaat
    38281 ttgcgcaaca gtaacgtccc cccggcggag acgctggcga tcctgaaaaa taaactcagc
    38341 tcgatttttg aatacggtct ctatagccgc gacagcgtgg cgcatccgcc gcgctatggc
    38401 gaccagattg aagagcgcgt gacgctgctg attggctgcg tagagcaggt gttgggcttc
    38461 tcgctgccgg aaaatctggt taacccactg cgtaaacact tcctggcgct gataggctac
    38521 gtgcagcgcg gcctgatccc gcagctttac tcttccagtt tgatcctgga tcgctgcaaa
    38581 gacgaatatg acaacgccac gctgctgtgt cggaaaatca acgaactgct gcatatacag
    38641 tgtccggcga cggaagtggt ctggctatgc ctgttcctga aagagtgccg ccattatcgt
    38701 cagcgtatcg atgccagccc cgactgcggg gtcattttga tcgctcacgg cgcgaccacc
    38761 gccaccagtc aggcgcaata tgtcaaccgc gtgctggagc gcgagctgtt cagcgccatc
    38821 gacatgccgt ttgaacagtc ggtgcatgac acgctggaaa cgctgaccca aatgattcaa
    38881 acccgccaat atcggcggct tatcctgttg gtgggcatcg gttcattgat ccatttcggc
    38941 agcaccatca gtaaattatt ccagatagat gttttgctca tgccgaatat cacgctgacc
    39001 agtctactgg aagtcgggct ggatttaagc tatgaaacca gcgacttacc acagttgacg
    39061 gcgctcctgc agagtaaaaa tatcccctgc cagctttgta cgccgcagca ggagaacggc
    39121 ggcaaagtgc tggtcatctc ctgtattacc ggcatgggaa cggcggaaaa aatcaaaaag
    39181 gtgctggagg agagctttgg cgaactgatg tcgcaggaca ccaggatggt gatccttgat
    39241 tataacgagg tacgaagtct ggagcgcgtt cagcaggcat tgaatgccag cgagcggctg
    39301 gcggggattg tcggcacttt ccagccgggg ctgccggata ttccgtttat ttcgctggaa
    39361 gagcttttct ccgaacaagg gccggaactg gtgttgagcc tgttaacgcc cgatctgtcc
    39421 aacgctgaac gccgtctgga gatggagcgc agcgcgatgc gctttatcag cgcgctaacg
    39481 atggagagca tcatcaacca tatttctgtg cttaacccgc agcgtattct gaaagagatg
    39541 gagggcgttt ttaaccatct gacgtcttcg ctttccctga aaccaagccg ccaggtgaca
    39601 ctgcgcttcc tgatccactg ctgctgtatg gtagagcgta ttgtgattaa ccgaaaaccg
    39661 ttacagatgg cgctggaacg tcagccgaat ctggacgcgc gcgcgtttag tgtcatcaaa
    39721 tccgcttttc tgccgatcga agacgcgtac gccatccgtt tatcggatgc ggaatatttt
    39781 tatatctacg aactgctcta tagctaatcc ttttactggc ggggcttcgc gcctcgccag
    39841 acctttcttc ttcctcgcgt gacacaaatt ctggcacaac ctttgctctt ctgatgatgc
    39901 gttatgccgg atagcggcgt aaacgcctta tccggcctac cgggagtgtc ctgtcggtcc
    39961 ggtaagcgca gtgccaccgg gcaatatatg ccggtgttct catgtaattg cgccaggagg
    40021 ccattatttt gactaccaca caaccgttgc cccacatcct gctgctgacg catggcggct
    40081 ggggacaacc gctttgcaac agcctgcgta tggtcacggg cgaaattaaa ggcgtgacgg
    40141 aaatcgcgct aatgcctgtc gatacgctgg gcgagtttta tcaacgcgtc gaggccgtgg
    40201 tgaaaacgct gccggaaggc tcgctgatcc tgacggattt tgtcggcggc acgacgtcca
    40261 acgtcgcggc gcggctaagc gccgattatc cggtggcggt gattgccgga ttgaatgcgt
    40321 cgctactgct ggaggcgctg gacaggcgcg aacaagggat gctaaccgcc tgcgtggatg
    40381 agttagttga ggccgggcgc agtagctgcc tggatgtggt cgcccatgta cgtcagctac
    40441 aacaatcact ctaaggaaaa catcatggcc aatatcgttt tatgccgcat cgacagccgt
    40501 ctcattcatg gacaggttgt cacgaagtgg gtcggacaat ctcaggcgaa ccggatagcc
    40561 gttgtgagtg atgaactgga cgccgatccg tttatgaaaa atatctacct gatggcggcg
    40621 ccgccaaata tcaaagtgga ttgcttcggc aaccagagtt ttgccgctgc atggaaagaa
    40681 aatcagcttg gcgacggtaa cgtgctggtg ctttttccct cactggcggc ggtgcaggac
    40741 gccatacaat tgggctttga cgtcacccgc attcaggttg gcggtctcgg cggcgggcca
    40801 aaccgcaagg cggtttttca gaatattacg ctggatgaaa aagacgtcgg cattcttaac
    40861 gacctgaaaa accgtggcgt tcaggtattt ttccagacca ttccggaaga taagccgcag
    40921 ccgctcgacg atatcctgaa aaaattctaa ccctttaata gacacaaaat cattctggat
    40981 gcatcgaggc ggcaactgag tgaatcccct ggagcttact aaagtaagtg actggggtga
    41041 gcgaaggcag ccaacaaaga ggcagcctga aggatgaagt gtataggata acactatgga
    41101 taccttactc tttgcaagcc tgatggggtt gtattactgg tttgcccgtt tacgcctcgg
    41161 ctacaccttc tccgcgatgc tgttacaacc ggtggtgatc gcggtatttg tcgggctttt
    41221 gcttggcaat atgcagaccg cgatgatcat cggcgcaggg atgcagctcg tttatttggg
    41281 cgtgacctca acgccgggcg gcaacgtgcc gtcggacccg gcgctggcgg cctgtatctc
    41341 cattcctatc gcggtgaagg ccggtatgga cccaaacctg gcgatcgcgc tggcaatccc
    41401 gtttggcgtg attggcgtgt ttctcgatca gctgaggcgc acgctgaacg ccgcctgggt
    41461 gcatatggcg gataaacacg cggaaacggc aaacatggcg ggcatcatgc gttgcgcctt
    41521 tctttacccg gcattgctgg ggctggtgct gcgcttcccg gtggtctttg ccgctaacta
    41581 ctttggccag gatgtggtgg aaagtttcct taaactgatg ccgcactggt taacccactc
    41641 ctttgaaatc atgggcggca ttctgccggc gctgggcttt gccatcacca ttatggtgat
    41701 cggtaaaaag agcctgttgc cgtggtttat cggcgggttc ttcgcggtgt tatacctcaa
    41761 ggtcgacatc atggcgatgg ccatcttcgg cacctgtgtc gccttcttga ttaaaggcct
    41821 ggcgaaaaat gaaggagcag catgatgagc agtgacgtaa tgcaacatga actggttgag
    41881 cgcgcgcggg aaagcggggc gctgaccaaa gcagatatca ccaaagcctg gtttatctac
    41941 tggctgggcg ccgaggtttc cagctcctat gagcgcttac aaagcctgat tttctgcgcc
    42001 tcgatgacgc cgatcatcaa aaaactttac ccacaaaaag aggagcaggt agaagcgcta
    42061 aaacgccacc ttaacttctt taactccgag cagaccttcg gcgcggtgat tcagggcatc
    42121 tctattgcca tggaagaaca aaaaacgcgc ggcgagccga ttaacgactc gtctatcacc
    42181 ggcattaaaa cgggcctgat ggggccgctt gccgggatgg gcgactcgat tatctgggcg
    42241 gcggtgatgc cgctgttgat agcgatcttt attccgttcg cggcaaatgg cagcgcgatg
    42301 ggcggtatta tcccgctgat tctctacccg gcgatcaccc tggcgatcag ctacggtatg
    42361 gtccacaagg gatatacact ggggcgtgat tcgattatcg gcctgctgca aggggggcga
    42421 atcaaagaac tgatctacgg ggccaacgtg ctgggtttga tcatgatggg cgcgctttcc
    42481 gccagctacg tcaaaatcac cacgccgtta aaaattagcg ccttgaaaag atctgaagtg
    42541 gtggttcagc agatcctcga ctctatcgcg ccgggcttac tgccactggc ggcggtattc
    42601 gccatctact tctatctggt aaaaaaaggg ccgcgctaca ccaccatttt gctgtcgatt
    42661 gtcgcactga gcatagtctg ttcgttgttg ggagtgctgt aaatcatgac gccgaatatc
    42721 tatcaacaac tggggttgaa aaaggtcatt aacgcctgcg gcaaaatgac cattctgggc
    42781 gtctcaagcg tcgcgccgga ggtcatgcag gccaccgcgc gcgcggcttc cgctttcgtc
    42841 gagattgatg cgctggtgga aaaaaccggc gaactggtat ctcgctatac gggtgctgaa
    42901 gatagctata tcacctcgtg cgcctcggcg ggtattgcca ttgccgtcgc tgccgctatc
    42961 acccacggcg atcgggcgcg cgtcgccctg atgccggaca gtaccggtat ggccaatgag
    43021 gtagtgatgc tgcgcgggca taatgtggac tacggcgcgc cagtcaccag cgccattcgt
    43081 cttggcggcg ggcgcatagt ggaagtgggg tcgagcaatc tggcggcccg ctggcaactg
    43141 gaaagcgcca ttaacgaaaa gaccgccgcg ctactgtatg tgaaatcaca ccattgcgta
    43201 cagaaaggca tgttgagcat tgacgatttt gtacaggtgg cgcaggccaa ccacctgccg
    43261 ttgattgtcg atgccgcggc ggaagaggat ttgcgcggct gggtggtgag cggcgcggat
    43321 atggttatct acagcggcgc gaaagccttt aatgcgccaa cctccgggtt tatcactggt
    43381 aagaaaacgt ggattgccgc ctgcaaagcg cagcaccagg ggattgccag ggcaatgaaa
    43441 atcggcaagg aaaacatggt tgggctggtg tatgcgctgg agaattacca ccagggccag
    43501 acgaccgtga ccgcagcaca gttacagccg gtcgcggaag cgatttctgc catccatggg
    43561 ctttatgccg atatcgaaca ggatgaggcc gggcgtgcaa tctggcgtat tcgtgtgcgg
    43621 gtgaacgcat cagaattggg gctgaacgcg caggacgtcg aagcgcagtt gcgcggcggc
    43681 gagatagcga tttacgcccg caaatatcag cttcatcagg gggtttttag cctcgatcca
    43741 cgcacggtag ctgaagggga aatggcattg attgtggcgc gactcaggga gattgcagaa
    43801 catgcagcag attaattttt atcgtcagcg ggtagcgatt aacgtgctgg caaaggatat
    43861 cgccaacgcg aaggctatct atgaagccgc cgaaggccat gcggtcattg gtgtactttc
    43921 cgcgcagttc gctacggtag aagagggcgt gccggaggtg aaacgctgga tggcggaggt
    43981 gccgtctatc tcggtggggc tgggcgcagg cgacccggcg cagtactaca aagcggcgat
    44041 gattgccgcc catactcacc cggcccatgt caaccagacc tttaccggca gcggcttcgc
    44101 agcgggcgca ctggcggcga caggcggtga gcaaacacat attaacgccc tggtcagccc
    44161 gacgggaacg cctggcgagg tggtgatttc taccggcgtc agcagcagcc agggaatgcc
    44221 agcccgcgtt tcctgtgaag cggcggtacg catgatgcag gatatgggcg cacatgcggc
    44281 gaagtttttc ccgatgggcg gcgaaaagtc gttaccggaa ctctatgcgc tggcgacaac
    44341 cgccgcccgc cacggcatga cgctcatcga gccgaccggc ggtatctcac tggataattt
    44401 cggtattatc ctgcaaacct gcctggaggc aggcgtgccg cgcgtcatgc cgcatgttta
    44461 cagctcgatt atcgatccgc aaaccggcaa tacgcgcccc gaagacatca ttcagttgat
    44521 ggagatagtc aaagcgctgg tgtgagattt atcgccgaag agcgctacgt ttacctggcc
    44581 tacagatgac gtgtatttgt aggcccggtt agcgttacgc taccgggcga taatgcgtag
    44641 caggctgagc aaaaatgtac gtattgcagc cgtcagtgat tccctttcga gcctcctcgc
    44701 agggttaaat tttcctgaat gctgtctgta tttttggcga gtacagtggc gtcatcttat
    44761 tcctcaggtg acggatcgcc atgaaaaaaa gccccacgtc cacgcctcat gatgcggtat
    44821 tcaaaacgtt tttacgccat ccggataccg cgcgggattt tctcaatatt catcttcccc
    44881 atttgctaag aatacgttgc gatctgacga cgttgaaact ggcgccggac agttttatcg
    44941 agaaaaattt acgcgcgttt tattccgacg tcctttggtc gctaaaaacg tgtgaaggtg
    45001 acggttatat ctatgtcgtt atcgagcatc agagtacgcc ggacgcgcat atggcgttcc
    45061 ggttaatgtg ttacgcgact gccgcgatgc agcgccatct ggatgctggc cataaaacgt
    45121 taccgctggt gattcccatg ctgttttacc atggcgcgaa aagcccgtat cccttttcgc
    45181 tttgctggct ggatgagttt ggcgatcctg cactggcgcg tcagctttat gcgacggcat
    45241 ttccactggt agacattacg gtggtgccgg ataacgagat tatgcagcat cgacgtatcg
    45301 cgatgctgga actggtacaa aagcatatac gtcagcgcga cctgatggga ttggtcgagc
    45361 gtttagcggt acttctgatt acgggaaacg ctaatgacag tcagctaaaa gcgctgttta
    45421 attatttgct aatacagcat ggcagcacgc ctcgttttgg caagtttatc cgcgaggtgg
    45481 cgcgttgtgt tccccaacac aaggagagat taatgacgat cgtagacaga atacgtgaat
    45541 cggggcgcag aaaaggtaag cgtgaaggcg tgcaacaagg catacagcaa ggtatacatc
    45601 aaggtaagca ggaggaagcc ttgcgtattg cgcatacgat gctggaacag gggatcgagc
    45661 gagagatggt gctgatgatt accgggcttt ctgacgaaga gattaaggca aagcgccatt
    45721 aaacttttcc ctcttccgcc cggtcatcgt gattatcaac ggcgttaagc ggcccgcgcg
    45781 cgtcgacggg aatcgaggga gatcagaatc actgacgaga gaatgagcag cgtgcccagc
    45841 cagtccggca aggtaaaact aatccccaac agcagcagcg acagcagggc gctgcttaac
    45901 ggttccgcgc agcttaaaat gctggctttg gggccaccaa tcagctgcgc gcctttcaaa
    45961 tacaggctga acgtcagcga cgtaccgatc accaccaggt agaaaaaggc cagaatcagg
    46021 ctgccgctca ccgcaaagtg cgttccttct ttagcgtaga agggcagcag aataaggccg
    46081 ccaaaggaca tactccagcc gaccactggc agcgtgccgt attgggcgat tagcctggaa
    46141 ggccaggtcg tataaaaggc ggcggcaaat gcggaggcga taccccagaa cagcgcgcct
    46201 gaagagatcg acagcgatgt tggattgccg tgagtcacca gtaaaaaggt gccgataagc
    46261 gatgtaagaa tggcggttaa gaccagaatg cctggtcgtg ttcttcgcgc taatgcaaac
    46321 cacgcgacaa taatggtcgg cgataaaaat tgcagcactg tcgcggtggc ggcattggat
    46381 ttttcaatcg tgagcaggaa ggttagctga acggtgagcg cgcccaccac ggagaaaatc
    46441 agcagactca gtgcatcttt gcggttttta agaatcgaaa atatcttatc gccgtgcata
    46501 aaggagaagg tcaccagtat cagcccggcg aataacaaac gtatcatcgt caggaactgt
    46561 gacgacatac ggctttgctc catgatgtac tgcgcgcaaa cgcctgaact cccccacaat
    46621 acggcggcaa tcaggacgtt tagcatccct tttctggtgg aacccatttt ttcctcgtca
    46681 tgttgtttta tttttttacg tgcaggcatc ataacagagc tatcgccggc attaagcagg
    46741 aatttattgt ttaatgattt cagacgagcc tgttattgac ataatattgt catttttttg
    46801 tcacgggaaa tatcaaacaa acttaaacaa atcgtcacta tccccgcctt tgcactttac
    46861 agaacatatt gactgactat aataagcgca aattcatgca ggagtaatat gttggacagt
    46921 cacttttacg taaatcatct ggcaagttaa cgcacgctat tcctgcgctg cttgccgaac
    46981 cggtgggcag caatctcccc ttgtgacgat tgtcatccca ataatgttac aacacgcgca
    47041 ttgtcgcgag gtaatcgtca tgttcatgtt taaacacgct ttatttcctc cgccgttaac
    47101 acgacgctaa ttgcctcagg gcagaaattt gtcgtgtgct aaatatagca cgtacttatt
    47161 cttccagaaa aaatggagga acgtatgtta atgtttcctt atattttaaa tttactggcc
    47221 gctatgctgt tgggcgcgct gattggcgcg gaaagacaat ggcgtcaacg tatggcggga
    47281 ttacgcacta atgcgctggt ggcgacaggc gccgccgttt ttattctgag ctccatgacg
    47341 acatcgccag acagccccgg gagaattgcg gcgcagattg tctctggtat tggctttctg
    47401 ggggcgggcg tcatcatgcg cgaagggatg aatgtgcgcg gactgaacac tgcggcaacg
    47461 ctatggtgtt cggcgggcat cggcgtgtta tgcggcttag ggcagttcaa aaatgcactg
    47521 gcggcgacga tcattattct ttgtgccaat attttattgc gtgaagcggc gcagcgtata
    47581 aatcaactcc cggtatccgc cgaggcagaa aaacgttata tcctgaaagt aacctgtaat
    47641 aaagaagatg agagcgcggt tcgtcagtgg ttactgaata tcgtaaaaga ggccgcgatc
    47701 tgtttacaag ggttaggttc ggtccccgct caggaacagg gctataaaga aattcgtgcc
    47761 gagctcgtgg gtcatgctga ttatcgtaaa acgcgagaac tgattatatc cagaataggt
    47821 gataacgata atatcaccgc aattcactgg agcattgata gtcaataata gttttttatt
    47881 caattgcaac attacgccag gcgtataagg agggaatgat ggatattccc gagtcgataa
    47941 aataaaaccc actcaaaata gtgagtaagc aataaccttt tttatgcata gataattctc
    48001 ccggggcatt caccttcaaa tcgtgagttt actattccct gggcgtgata tgcaggaaac
    48061 actacacctt aattttgggg attcatcatg actgacatga acattgaaaa ccggaaactc
    48121 aatcgcccgg cgtcagaaaa tgataagcag cataaaaaag tatttccgat cgaagcggaa
    48181 gcttttcata gcccggagga gacactggcg cggctgaaca gccatcgtca gggcctcacg
    48241 atagaagagg ccggcgaacg gttgaaagtg tatgggcgca atgaagtggc gcatgagcaa
    48301 gttcctccgg tgctggttca gcttctgcag gcattcaata acccgtttat ttacgttctg
    48361 atggcactgg caggggtcag tttcatcacg gattactggc tcccgttacg ccgtggcgaa
    48421 gagaccgatc tcaccggcgt gctgattatt ctgacgatgg tcagtttgag cgggttattg
    48481 cgtttctggc aggagtttcg cactaacaga gcagcacagg cgctgaaaaa gatggtgcgc
    48541 accaccgcca cgatgttgcg tcgtgggccg ggcaatatag gcgcggtgca ggaagagatt
    48601 cccattgaag aactggtgcc gggcgatgtg gtttttctgg ccgcaggcga tctggtgccc
    48661 gccgacgtcc gtctgctggc gtcgcgcgat ctctttatca gccagttaat tcttagtggt
    48721 gaatcattac ccgtagaaaa atacgatgtt atggctgatg tggcaggtaa agacagcgag
    48781 caattgcctg acaaagataa gagcctgtta gatttgggca atatctgtct gatgggaacc
    48841 aatgtaacca gcggcagagc gcaagcggtc gtggtcgcga cgggaagccg tacctggttc
    48901 ggctcgctgg cgaaatccat tgtgggtacg cgtacccaga cggctttcga tcgcggagtc
    48961 aacagcgtga gctggctgtt gatacgcttt atgctgatca tggtgccggt tgtcctgctg
    49021 atcaatggtt tcagtaaggg agactgggta gaggcttcgc tgttcgcgct ggcggttgcg
    49081 gttgggttga cgccggaaat gttgcccatg atagtcagtt ccaacctggc aaaaggcgcg
    49141 attgcgatgt cgcggcgcaa agtgatcgtc aagcgcctga acgctattca aaacttcggc
    49201 gcgatggatg tgctgtgtac agataaaacc ggcaccttaa cccaggacaa tatttttctg
    49261 gagcatcatc tggatgtgag cggtgtaaaa agcagccggg tattgatgct ggcctggctg
    49321 aatagtagca gccagagcgg cgcccggaat gtgatggatc gcgccatact gcgttttggc
    49381 gaggggcgaa tcgcaccatc gacaaaagcg cgcttcatta aacgcgatga actgccattc
    49441 gactttgtac gtcgccgggt atcggtcctg gtggaggatg cgcagcatgg agacagatgt
    49501 ctgatctgta aaggcgccgt tgaagagatg atgatggtag ccacccatct tcgcgaaggc
    49561 gatcgtgtgg tggcgctgac ggaaacacgc cgcgagctgc tgctggcgaa aaccgaagat
    49621 tacaatgctc agggattccg tgtattgctg atagcgacac gtaagctgga tggttccggg
    49681 aacaatccga cattaagtgt ggaggatgag accgaactta ccatcgaagg gatgctcact
    49741 tttctcgatc cgccgaaaga gagcgccgga aaagctattg ccgcgttgcg ggataacggc
    49801 gtggcggtca aagtcctcac cggcgataat ccggtcgtga cggcgcgtat ctgtctggaa
    49861 gtgggtattg atacgcacga tatcctgatc ggaacccagg ttgaggcgat gtcggatgcc
    49921 gaactggcgt ctgaagtgga gaaacgcgca gtattcgccc ggctgacgcc gttacaaaaa
    49981 acgcgtattt tgcaagcgct acagaaaaat ggtcataccg ttggttttct tggagatggg
    50041 atcaacgacg cgcccgcgct tcgtgatgcg gatgtgggaa tttccgtcga tagcgccgcc
    50101 gatattgcta aagagtcatc agatattatt ctgctggaaa aagatctcat ggtgcttgag
    50161 gaaggcgtta tcaaagggcg ggaaaccttt ggcaatatca ttaaatatct gaatatgacc
    50221 gccagctcta atttcggcaa tgttttttcg gtactggtag ccagcgcgtt tattccgttt
    50281 ctgccgatgc tggcgattca tctgttgatc cagaatttga tgtacgatat ttcgcagttg
    50341 tcgttgccgt gggacaaaat ggataaagag ttcctgcgta agccgcggaa atgggacgcg
    50401 aaaaatattg gtcgttttat gctatggatt ggcccaacgt cttctatttt cgatatcaca
    50461 acctttgcgc tgatgtggta cgtttttgcg gctaataacg tagaggcgca ggcgctcttt
    50521 cagtccggct ggtttattga ggggctgctc tcgcagacac tggtcgtgca tatgctaagg
    50581 acgcagaaaa taccgtttat ccaaagtcgg gcgacgttgc cggtattatt gacgaccggc
    50641 ttgattatgg cgataggcat ttatattcca ttctcacctc tgggcgcgat ggttggactg
    50701 gagccgctgc cgctgagcta cttcccgtgg ttggtggcga cattattgag ctactgtctg
    50761 gtggcgcaag gcatgaaacg cttttatatc aaacgctttg gccagtggtt ttaataatgt
    50821 ttgaggatcg cccagatgaa tcgctcaccc gataaaatca tcgcgctgat atttttactg
    50881 attagcctgt tggtgttgtg tttagccctc tggcaaatcg ttttctaacg aggtgacgcc
    50941 atgcaaaaaa gagggttgga caaaattttt tatcaggttg tcctgatagc aatcatcctg
    51001 attttactga ctatctggat acgataagct gccgttggcg agccccgctt aaaataagaa
    51061 tcgatgtagt tgttcttttt atggcggggc gctattttca tggtatccca catgagaagg
    51121 gcaatatcat gaataatcgt cgtggtttaa ccgccgtcct ggcgacgttg attacgtttt
    51181 ccctgagcgc tacgcctgtg ctggcgaatc cgggaaatgg caatggcggc ggacatggta
    51241 ataacgcggc taatcagggt aataacggta acggacataa aggaaatgcc gggcaaaaaa
    51301 cggaacaccg taaaaatggc ggtaaaccgg atcacgtcga gtcggacatt agctacgctg
    51361 tcgccaggca actggcagtg aatttagggc tgacgggtta tcagtcttta cctccgggga
    51421 ttgcgaaaaa tctggcgaga ggaaaaccgc tgccgccggg aatcgctaaa aaacggtgcc
    51481 ggcgtctatg ctgggacaat taccttatta tccgggctat gagtggaaaa tcgttgggga
    51541 taatctggtg ctgatcgcgc tcagtaccgc ggtggtcacg gcgattatta atggcgtatt
    51601 tgattaagag cctatcccac caggcgttat tggcgcagcc agtttggaca cggacagcgc
    51661 gcaaaaaccg gagcgtacac gtagtacgtg aggtttgact cgctacgctc gcccttcggg
    51721 ccgccgcaag cggcgttcaa aacgctaacg cgttttggcg agcactgccc aggtccaaaa
    51781 tggcaagtaa aatagcccca atgggatagg ctctaagcgt gttgtagtcc gatgacatgg
    51841 cgctcatcta ctggttgtag gctgaataaa caggcgatag ataaaatagc cccattaaat
    51901 ggggctattt agccgcttca gggcgttatt tatgcgcgtt gagaatccag cagttcatta
    51961 ttttttacta cttcctgcgc tttggtataa ctttcaatca gtagctgata ggccgggaat
    52021 attttggtat atacatccgc ccattctgcg gcatcttccc gattccaggt acgttgcagc
    52081 tcagaggcta ccgccgcggt atccattggt actacgcccg cctgcaccac gcgggccatc
    52141 gtaatttcct gcgccatttt actgtacgta ccggaggcat caattaccgc aaataccttg
    52201 tacccttccg cgacggcgct gatggctgga aaagccatgc agacactggt aatagtaccg
    52261 gcgatgatca gcgttttacg gcctgtcgct tttaccgcct gtacaaaatc ggcattatcc
    52321 caggcattaa tttccccttt acgcgcgaca tattgcgcgt ggggcgcatt cgcatggatt
    52381 tccggaatca gcggaccatt tggtccctgt ggtacggatg cggtagtaat gaccggcata
    52441 ttgcataagg tagcgatttt agccagcgcc gcggcgcgcg cgcgtaattc cggcatcggc
    52501 atgtcgccga cggtctgaaa caggccactt tggtggtcaa tcagcagcat gactgcgtcg
    52561 ttagcatcaa tggcagggcg ttgaccgtta aaattcgcgg gtgtagacat aattcattcc
    52621 ttgttgttgc ctttcactga tagtcactat cagtgttaaa gtcattaatc gccggggcga
    52681 tttccgtttt taagctgatg acagtaatcc gttgccgatt ctggattacc ctgttgagtt
    52741 ctttctgaag gaatattcat cggcatcacc ttcagtcaat ttactttcac gcgaatcggt
    52801 tatcacaaca atattcatat tatgattaaa tgtttctatt ttacatgtca gagaggatta
    52861 ttgattgaaa aaacaggcta tatccc
//
LOCUS       DAJVKX010000015        52426 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000015 DAJVKX010000000
VERSION     DAJVKX010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 52426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52426
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.015"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            122..364
                     /locus_tag="OPY25_000838"
     CDS             122..364
                     /locus_tag="OPY25_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926517.1"
                     /translation="MISKLPRDKDCNDSDSSSRKSVSEKIIESIAEKQKINQEIMKID
                     LEIELLRTKKGNMTAQDYDSKMRELTNKHSALKRKI"
     gene            588..977
                     /locus_tag="OPY25_000839"
     CDS             588..977
                     /locus_tag="OPY25_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000993573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926518.1"
                     /translation="MNAQARGARAARLYKRAKSKLISLDHFCVQKAREHKLPAWTGHL
                     PVTTLTGILFAAVIFGSLLFVSLGLFIFALILVTSWPGKRTNSADSWSDNSWGSSMRD
                     GSEGFGLYTGPENSHILTSRIDNEDDL"
     gene            complement(1013..2518)
                     /locus_tag="OPY25_000840"
     CDS             complement(1013..2518)
                     /locus_tag="OPY25_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG N-terminal
                     domain-containing protein"
                     /protein_id="HCS0926519.1"
                     /translation="MTTSSYLEYILTILGWVVNNGLWDVLTGTGLFALPLGFKIIGIW
                     IKTREEGDDEGNKGILSARRMEHAIYGAFIVIIACCVPTQTVSLTTLTFDTTRAKQCG
                     FWTPVKPGDSGYGSVVSTMSGMTASAPVWWAFMHMISKGVTQAAVASLPCRPDLRQVR
                     FDVQHTQITNPALAQELQDFTSDCYAQAFALWKRQDAGRTTDIDVLRDIEWLGSKIFL
                     KDFYPQLHSKLPRSAFPWSQSRDDGYANTGQGGYPTCSEWWSQNKTGLKSRVLDTVNT
                     TTMTRMAAAFKGMVSKEEYTEALIRRLVSPTSLSVSQNGRTYAGYGGNADFTLDNAVN
                     RMASVLGTSVGALGAFPAFDAMRQALPMVQALLLMAMYVLIPLVLVFGTYEYKTVVTL
                     TFVTFGMHFLTFWWELARWLDSWLLEIMYGSDSHSRWNVAGFQNSADDLIMNFVMGTM
                     FLVLPAVWMGALSWAGVRIGGIVDTNLNKGVQPAGQHGGKVGDKIGSGIAK"
     gene            complement(2851..4281)
                     /locus_tag="OPY25_000841"
     CDS             complement(2851..4281)
                     /locus_tag="OPY25_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrating conjugative element protein"
                     /protein_id="HCS0926520.1"
                     /translation="MRSQSILSVCLMLGIVSSGPLSAALLDAPTLSGDGYGKSVNGAV
                     SDKLFYSIGGGSVISTPGTMYGMKRIGLDAGLSSDLMCGNFDIKTTVGNQLNGVTNGF
                     KDLMGDVITGATGAVSSMPAMILQRANPGLYEMITNGVLQAGLAFDKSKLNCESMANK
                     LADYTLGDKSSWTESAVREEYKEAVSASGGDALRAEEARTKASGKEGATWVGGKKAGG
                     KGQPAIQPTRDLAKAGYNMMNNLSVTSNSTVSAGSCKGSACQKFKNSEEAAAAVVKVL
                     GDRSIRTCKDATECGSGGIDNAQGTTIAGTGFAPMLEDTTKENLEQLVKLVNGTEAPT
                     QANLDKIKSGSLKVTRGVIDALKRDPDAGALVQRLAGELAMSDTIETGLAMRRMLTTG
                     QSEPNAADQPQAMAEADRRIEALDRELNSLKLEMELRREVAKNTALVVVAREENRSVT
                     NPQKESQTNADTRLSELETRKPGDSQ"
     gene            complement(4296..5264)
                     /locus_tag="OPY25_000842"
     CDS             complement(4296..5264)
                     /locus_tag="OPY25_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03756 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926521.1"
                     /translation="MKSLRLKRALLSVMLITGGMEVQAALNTASIVASSISPSCISWR
                     ISGICYWLMCTPFGCTVKTSIKVHHFIPEAVVSTYQASGGNPWTEMSLVSQTAGGVEN
                     AVTGALSGLAAGGGNQEQKFPGTRKSNVRFKYADAIGHPSTSIIGGQIPGYSCNSAAT
                     PLVPYFLSTLDTLAWRTGVPESVYPEALIPGRREIGSTSAQNIWGNLYPRSGFVTQQD
                     DYKSGAIVAQRVADIITRTNQIHVYKPLTGNPSAGYWPPEPVKENTGTQNHKWQQLSP
                     TLSMSCSVFPDTGKIAENGNYAWTLWQPYSCCKRRGQTFLYSTDIN"
     gene            complement(5261..5653)
                     /locus_tag="OPY25_000843"
     CDS             complement(5261..5653)
                     /locus_tag="OPY25_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03757 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926522.1"
                     /translation="MKRILSSLILISSFSASAQIVVYTDQGHPPVGVTPAIRVVYLDA
                     SERWLQQQFGELSSDPEQAVRQAHSLLNSPDWKRRQKALIEHYRGMIEAWQLGLLKYP
                     AVVFDNRDVVYGTVDISRAVALRRGENQ"
     gene            complement(5808..6194)
                     /locus_tag="OPY25_000844"
     CDS             complement(5808..6194)
                     /locus_tag="OPY25_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926523.1"
                     /translation="MSLLKHEQWLILGEDESHRIPPDALLGLPPQGKAWIRKEHDEDM
                     SRLTSHIQGALGNTYRGVCHPQRIGHRACLAIHLENLRGKKLDILITVSGKTALPAEE
                     SYVNPRWYIDVADAADALYLALWLIR"
     gene            complement(6349..9185)
                     /locus_tag="OPY25_000845"
                     /pseudo
     CDS             complement(6349..9185)
                     /locus_tag="OPY25_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253395.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer ATPase"
     gene            complement(9185..9634)
                     /locus_tag="OPY25_000846"
     CDS             complement(9185..9634)
                     /locus_tag="OPY25_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03751 family conjugal transfer lipoprotein"
                     /protein_id="HCS0926524.1"
                     /translation="MVLTDNQKITSRTVKITPVLFFIAGMFSVALGGCSSSKDELLPP
                     GDSSMMELWQGNAPTSHAVVKGRETLRRSLSSQETLASGRIDESYSRTQENELSQIFP
                     RLPNPDMVMYIFPHLANGNTPVPGYSTVFPFYAQTQYALPGERTEAL"
     gene            complement(9621..11099)
                     /locus_tag="OPY25_000847"
     CDS             complement(9621..11099)
                     /locus_tag="OPY25_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03752 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926525.1"
                     /translation="MQIKANGLMKVLLPVLIVVVCFIGVKACGLKDTTEPEPAKTTNA
                     LTELSQDDLKALGIEGDTSADTLRTLIGALRDVRARQAVLDEQNKALISENNKLKGEN
                     SSVGLQISNAVNAAKQETNEALEKQKTFLLEKLNDLTGTLKSQGQNTDMVSTGSSSGT
                     DFPVGLGLDPENASSATQGEVIWISPQDAKKTEGQSQSDNDKFTFPTSFLDDNPVSRQ
                     RAEYDRVVKNKQELDGNGAESDTRPVYTLPENSTLVGSKAMTALIGRIPINDKVTDPY
                     PFKVLIGKDNLTANGIELPDVEGAIVSGTATGDMVLSCVRGTIHSITFVFSDGRIRTL
                     PRPVANTQGNNNDNAGDRGSIGWISDNNGIPCISGERKSNASTYLPTVALLGMGSSAG
                     DALTQNQYTTQNNVNGGVTSALTGNAGQAVLGQTLGGGFKEVTDWVKQRYGQTFDAVY
                     VPPGANVAIHITRQLAVDYEDHGRKVRYDFSLPGTGGHYGLD"
     gene            complement(11089..11988)
                     /locus_tag="OPY25_000848"
     CDS             complement(11089..11988)
                     /locus_tag="OPY25_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03749 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926526.1"
                     /translation="MAMFKVLNFKCKWWPIILLLWFSSAQAVELMKWERIPLLIPLSV
                     NHERIVFVDRNVRVGFPAMLKGKLRVQSSGGTVYLQASEPFEQTRLQLQDVESGEIIL
                     LDIAAKNDNKALEPVRLVYSGEVLSVSEKGMETGSSLPVASLDTEDKNQTVRKTPVYS
                     APLPVVLTRYAAQSLYAPLRTVEAVPGIHPVNLRLPSRLTTLYPSENVVVSPIGAWGI
                     QELNVVALKIRNRSSSKVILDARTLSGSFVSATFQHRWLGAAGTPEDTTTLYLVIRGR
                     PENAFIAEPAVLPAVKKGEQHAN"
     gene            complement(11988..12641)
                     /locus_tag="OPY25_000849"
     CDS             complement(11988..12641)
                     /locus_tag="OPY25_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016808259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03746 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926527.1"
                     /translation="MSRFRHALKDRDQHILTLRLACGVLLLLLILVITGWMRAPSDLT
                     IHNPPDLRSGSTRKWWEVPPSTVYSFAFYIFQQINAWPKDGEKDYPMKIAQLSPYLTP
                     SCQDFLNKDAELRSQKGELLDRVRVVYEIPKRGYKPESVIIESDDSWEVSLDLVVDEY
                     YHTEPVKRALARYPLHIVRWEGDPERNAFGLALDCYKGVPQRLEAAVVPEPEKKGMF"
     gene            complement(12638..13012)
                     /locus_tag="OPY25_000850"
     CDS             complement(12638..13012)
                     /locus_tag="OPY25_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03750 family conjugal transfer protein"
                     /protein_id="HCS0926528.1"
                     /translation="MKTIEFLPDRLNAETVVFRGFTTPELGYAALIGAVSGLILSLIM
                     MLVTGIGWPIIPTCTLITPLIFIFIGGRFLVRFKRNKPNFYLYLRIQKILSHIGIGSK
                     VLVRHDRRWSLRRSKPVRKGGI"
     gene            complement(13022..13384)
                     /locus_tag="OPY25_000851"
     CDS             complement(13022..13384)
                     /locus_tag="OPY25_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03745 family integrating conjugative element
                     membrane protein"
                     /protein_id="HCS0926529.1"
                     /translation="MLSKSKHGLRVPLPCLLILLLLVASFSSHAGLPTVNIPGGGGGG
                     DMMQTIKLLFSGFLVLMGLIICAVGFYMVSGAILATFSEIRSGKAEWGKFVAIVVVGI
                     AILVVIVWLCTEAAKILN"
     gene            complement(13414..13653)
                     /locus_tag="OPY25_000852"
     CDS             complement(13414..13653)
                     /locus_tag="OPY25_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03758 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926530.1"
                     /translation="MAMNSEQANAFKAGSGIDPTVLNKFVLGFVLSVLFLWFAWSVLV
                     VFRGWRAGKVTEQNALHFFISTAILVVFSVWMFAS"
     gene            complement(13653..13907)
                     /locus_tag="OPY25_000853"
     CDS             complement(13653..13907)
                     /locus_tag="OPY25_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015701164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926531.1"
                     /translation="MVSAAEKDELALALRQLDQVQSALERAKIVAVQDNSDGRFFFDY
                     ERATRDLKTMKQGIETYLEPSRAQPRDKGSLVGQYRKEQP"
     gene            complement(14144..14902)
                     /locus_tag="OPY25_000854"
     CDS             complement(14144..14902)
                     /locus_tag="OPY25_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03747 family integrating conjugative element
                     membrane protein"
                     /protein_id="HCS0926532.1"
                     /translation="MSTEKNSSQSSPPPRKPPGLLTLVLWIWPVRLLAFLLVSWMAGV
                     FIEWAGMFFFWSDQGALHSQSVMNKELGYLSADFTQSLIFSSPSVTTMGWISSAYQWA
                     FVDSGLLTWIQKEQRETLSSSDSVVFFLGQVQAWLLSVLSDYLLALVYVTVVFAVRVL
                     ILVLSIPLFVLVIIVAVIDGLCRRDLRRYGAGYESSFLYHHAKRFVKPAVYLPCLLYL
                     SWPASIYPNLLLLPGALLLGLAVTVVTSTFKKYL"
     gene            complement(14899..16989)
                     /gene="traD"
                     /locus_tag="OPY25_000855"
     CDS             complement(14899..16989)
                     /gene="traD"
                     /locus_tag="OPY25_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HCS0926533.1"
                     /translation="MSNRYVMEALLRPAVELYSAAAGGAATFVLVVAPWSMALAPQVS
                     YVTAAGFAIFTTIRTRQGLRILRYRRNIRRLPRYQMSSESIPVSRHFLFLGKGFMWEQ
                     KHTQRLLETKRPEVAPFLKPSVFYSLARQFERRYEYTFPGLCSLTRRDSFFNPVRPLP
                     PVGGNSAIHGVEMEEDNVLMSLTERVGHLLVLGTTRVGKTRLAELLITQDIRRGNVTI
                     VFDPKGDADLLKRMWAETRRAGRSDEFYIFHLGWPDISARYNAVGRFGRVSEVASRVA
                     GQLGGEGNNAAFKEFAWRFVNIIARALVVLGLRPDYSLILRYVTNIAELYETYAEKLL
                     TQQAPELWLMVQNQMGILTEDDLPRTMQGQVNAIRVMAIEVALSSEQGKKIYDPVLDG
                     LRSAVRYDRTYFDKIVASLLPLLEKLTTGKTAALLSPDYSDMNDPRPLIDWQEIIRKG
                     GVVYVGLDALSDSEVASAVGNSMFADLVSTAGYIYKFGLSDDMPEGSSQRLPISLHCD
                     EFNELMGEEFIPMINKGGGAGIEVTAYTQTWSDIEAKIGNAAKAAQVTGNFNNMIMLR
                     VREKTTAELLTTQLPEVEIYTKTLVSGVTDISNPDQGSDFTSNVQDRVSSTRVPLLSP
                     AEVMNLPKGQAFALLEGGRLWKIRMPLPASVDDEMMPVNLQSIVTTMRKHYRTGDTWW
                     SGSVLPGDNLVDAL"
     gene            complement(17009..17578)
                     /locus_tag="OPY25_000856"
     CDS             complement(17009..17578)
                     /locus_tag="OPY25_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HCS0926534.1"
                     /translation="MITAILLLLFCLLIPAIWRKKMPSARDRRHRRYRQNAERVLCRL
                     TALDSDGARLKYLRKINPYVFEELLLLAFERQGLLVVRNQTYSSDGGLDGQVFIDGKR
                     WLIQAKRYRRTISPQHIREFGELITREQCCGFFIHTGRTGSKSVNYLQCWRTIQLISG
                     QRLLDLLAGRQCWYHRPVTKSVAGQPVVT"
     gene            complement(17588..18088)
                     /locus_tag="OPY25_000857"
     CDS             complement(17588..18088)
                     /locus_tag="OPY25_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrating conjugative element protein"
                     /protein_id="HCS0926535.1"
                     /translation="MVSILLTTSSMAALNVIADLGGEPTAPLFDAINNKNNEFTPPRS
                     LNATGASVTAAPADVSDMLPVTTPEMRAGKVEARELNLNGMTPVFLVGDDSLSREWLT
                     MRRDELKRLHATGLVVNVSDKDALSELQQIIPDVILLPASASEIARRLHLNHYPVLIT
                     ATGLAQ"
     gene            complement(18124..18810)
                     /locus_tag="OPY25_000858"
     CDS             complement(18124..18810)
                     /locus_tag="OPY25_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HCS0926536.1"
                     /translation="MANRSILTAARYSVPVLILLIGGVGSAAAVEKGRGLQTIPPGYH
                     LVATEVGVPAEALYSVSLAETSRKLPHGERPWPWTLNVAGKGYRYNSRQEAYDAMLSF
                     MRRYPLKRIDVGIAQVNLGWNGTYFSSYYEALDPYTNLRVAARILKSCYDNNPGSWIQ
                     AAGCYHHPAGGKPARIYKSIVKRKLATLDLNAPVTYSELQIAQISPSQRHFSHYNREL
                     QWVEPRESRQ"
     gene            complement(18789..19529)
                     /locus_tag="OPY25_000859"
     CDS             complement(18789..19529)
                     /locus_tag="OPY25_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001768408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03759 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926537.1"
                     /translation="MKPMKSTLNCLRQWTASVMLAVIVSLPALASVSTGRSVSAPQQQ
                     NTTTEGRTQTSGTAWGLSEKEWQQYQQVLKGPRAFQSPGIDPLMALGLEAGSASERRR
                     FAEMWVKEEYARGEKELAFQREVDAAWKRLYPNTLSVNMGNASGIAHDTQGRLALFVK
                     RNCVPCDARVSAVLADNRPVDIYLVDSGGSDDTIRQWALAHHIPVDKVRSRQITLNHD
                     NGNWLKYGQGYMPVMLQQGVSGWQIAAF"
     gene            complement(19548..20462)
                     /locus_tag="OPY25_000860"
     CDS             complement(19548..20462)
                     /locus_tag="OPY25_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926538.1"
                     /translation="MTTTTASSVDIPSDNDLPLSAHLTEPAEPAIDTSDITVTPDTSA
                     QSAAYRLGGKRSRLWHPSSDRRSLIFKVSSVLVYCLLLGAVLFLWLTVRQQQIQLTTL
                     DAAFRSGQLQTLPDRMQAIEDRQQQFVPKLQGEKWQLRLSEQELRLTAFEQQLSSLVT
                     EVKETQAATARAVAREDETGMKLDAVHKALTEQTSRIDTLASWKDTWSKRTVATATKA
                     TPSPGGGQSAAKKSSKPRVIKPPFTLVSIERRGGQAYAVILPAGNSGWTQLRMVSPGE
                     SLSGWVLVNISGNQAEFQVNGQVQRLTL"
     gene            complement(20419..20781)
                     /locus_tag="OPY25_000861"
     CDS             complement(20419..20781)
                     /locus_tag="OPY25_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926539.1"
                     /translation="MQAWLNELAGAYRRVEVMTYREIITALPALPADGEWWRRSLRGV
                     GRQRAPSTLYLHIAHIFKRLPVCVPDANLDPLFSLLSFDLSVVSAELFLHSHGENRFP
                     EDLYHDDNDGIFCRYSVR"
     gene            complement(20969..21844)
                     /locus_tag="OPY25_000862"
     CDS             complement(20969..21844)
                     /locus_tag="OPY25_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926540.1"
                     /translation="MNATYNALIALMRSGEIPLETGASVSAPSAQFSVRIRPETRVFL
                     DRCAEHLGISRAAMFGMCIDGIVAEARESIADRTSTLYERFCLLLDAHGLNVIEQAQL
                     LASWGIRASVLASQDRTLDLLNKPLLQQLSTWFDVDVNWLLGNSSYPVDMADGQRDWA
                     VQTPSLLCRLQSIQSVDPVELIFFWQQGRKPQSVGLCLRYRPLISGEPIGLLRVYQAL
                     DWQDEQVQQAYNQLRRITSITLGGYTKDKVEKYPPIRLRYFTFSARQMQALDNGAVIP
                     AMIFDKPKGEFPSIS"
     gene            complement(22056..22523)
                     /locus_tag="OPY25_000863"
     CDS             complement(22056..22523)
                     /locus_tag="OPY25_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926541.1"
                     /translation="MEYALFVMFCLALYCPCFTLIALFTPWKGFAVFSVTYRRRQYWA
                     VHLALLDRVGAMNRRQARRYHQAFVQALETALVARPVRPVFFRSHLMRPAQVALTCQV
                     LSHRTGYRCRIAPITLPRWERVAIFAQMLLQEWRLIQLPSEEGIMVVIHRLAE"
     gene            complement(22620..23771)
                     /locus_tag="OPY25_000864"
     CDS             complement(22620..23771)
                     /locus_tag="OPY25_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCS0926542.1"
                     /translation="MSRPQRIKKMSLSKALDKYYATVSVHKRGHQQEFYRVRVIQRHP
                     LAEKMMDEITTVDIASYRDDRLSQVNTRTGRCISGNTVRLELALLSSLYNLASVEWGT
                     CRTNPVEMVRKPKISGGRDRRLTSQEERRLSRYFQEQNPALHAIFHLAIETAMRQGEI
                     LSLRWEHIDLQHGVAHLPMTKNGSSRDVPLSRKARHLLQGMTVALSGNVFHYSSSGFK
                     SAWRVALQRLNIVDLHFHDLRHEAISRLFELGTLNVMEVAAISGHRSLNMLKRYTHLR
                     AYQLVSKLDARRRQTQKIAPYFVPYPACIESVNEGSDGCCGFRVHLPDFDNLSVSAAS
                     RESALEAAGVLLLRTLAKAAQRGERVPRPGDLPEGKHERVMIHPLLSAA"
     gene            complement(24119..25426)
                     /gene="pilV"
                     /locus_tag="OPY25_000865"
     CDS             complement(24119..25426)
                     /gene="pilV"
                     /locus_tag="OPY25_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="HCS0926543.1"
                     /translation="MKKQKHDGGFVAMSVGAGLLIVLVMASLAARYMGDYLKSREWQV
                     VAMQTNRFTQAVSSYVGKFYPTVLASATTTTPAVVTTQMLKNTGLLPASFSETNSYGQ
                     QYQAMIVRNQQNQELLQGMVVSRGGHAMPFTALSQISKDITAGFGGYVEDGQTAVGAM
                     RSWRIPLSSYGTSTGRGHLAVMLSTDDLSGAREDGDRLYRFQVNGRPDLNKMHTAIDM
                     GGNNLNSVGTVTASNVAGQNGNFGVSLVSNGPITAGGDIRSTGGWIVTRSGKGWMDET
                     HGGGLYMSDNDWLRILNNKGFYTGGEIRGGKIRSDGDVSAGGILTLDKINVASTACPV
                     NGAISRDTAGATLSCQSGIWSSYRLNFNIQTFNVGKNVRNQYIGVHAYCAWTYLNGSP
                     LGGFQEIHSNGSNGWYISNYRWGNYESGGTISVTCLNLPGAGL"
     gene            complement(25423..26085)
                     /locus_tag="OPY25_000866"
     CDS             complement(25423..26085)
                     /locus_tag="OPY25_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCS0926544.1"
                     /translation="MTVSLIGTIFPPVYAIPAFIGCAIFGAVLLRPVRLYLAAAEVDI
                     SRHCAVVVGIWLFAVTGLLILMAPQVWMTRIGMLFMCSFLLQLGVMDATSGWLPRPFT
                     AACLCSGLLFCLAFHREPELRFMETAAMAVVMGSICHGVNRRRPQLGVGDVWLVCALV
                     GWMGVTDALQAAFFGLSGFMLWQWIVHRDFLRCGVLGPWLCAGCIPVIVDRLYQPEWI
                     LR"
     gene            complement(26082..26558)
                     /locus_tag="OPY25_000867"
     CDS             complement(26082..26558)
                     /locus_tag="OPY25_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000334696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HCS0926545.1"
                     /translation="MCGYFSRLALFMTLCSVPLWVQAFCFDAAAAKYHVSPLLIKSMA
                     IGESNLDPHATNDNRDKKTGKIKSTDYGLMMVNSTHIPRLVSMGVIRDKNDLLNKPCL
                     NVQIGTWILAKHFQVCGVSWNCLGSYNAGFRPDRHETRERYANRIWKIYQRQTGAQ"
     gene            complement(26568..27161)
                     /locus_tag="OPY25_000868"
     CDS             complement(26568..27161)
                     /locus_tag="OPY25_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilX"
                     /protein_id="HCS0926546.1"
                     /translation="MNEVSTLNPCNRPDRGMSADAGATALFILVIIGVIAAAVWSMWG
                     KKDAGTELTNYQTLATNTIGMMKGVDGYAFTSGAKMTDTLIQAGAAKGMTVSGDPASG
                     SATLWNSWGGQIVVAPDTAGGTGFNNGFTITTNKVPQSACVSISTGMSRSGGTSGIKI
                     NGNNHTDAKVTAEIASSECTADNGRTGTNTLVFNYNG"
     gene            complement(27203..28288)
                     /locus_tag="OPY25_000869"
     CDS             complement(27203..28288)
                     /locus_tag="OPY25_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HCS0926547.1"
                     /translation="MSPLYRLRRALARRFFTSGYRLRFYRMLSLQMRNGVKLLEALEQ
                     ISNMYTDFGQRTHGFGFLVDDCRAALTDNSGDNSLEHALANWVPAEEAALISAGMFSG
                     RLPEALAEAEILIDCRRRIRQAIMRMAVYPLGCIAMLGGTLGVIQTQLIPTLAGMSDP
                     QTWTGVLGSLNGLLIFFTEHGVVMGAGLALLVAWTRWSLSNWIRPDRLRRLADRHVPW
                     AVYSDIQGAIFLINMGALLCAGVRTLTALQVIHRFASPWLVVRLNAVMEEVEEGASFG
                     MALRECGYAFPSKEAVNYLSMVSGDGAAQMIARFGQEWLEETVKRVNRRGIAVMLFSM
                     VMLFALIGVVVVAVIEATSMTESMGQY"
     gene            complement(28285..30000)
                     /gene="tadA"
                     /locus_tag="OPY25_000870"
     CDS             complement(28285..30000)
                     /gene="tadA"
                     /locus_tag="OPY25_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCS0926548.1"
                     /translation="MSEHNDAVLLYHNPDTTILELLVDSQRRTDVAVQQKVMSLMEEN
                     PGVTMRLVTRSELLRYSEMARQQSEKGEKGLRLEDIKKEVSSRQGDVLNYFMVAKDIG
                     ASDIHGTTRPGLTRIEMRVHGELETVSELAEEDGKAQAATIILSMCDVTEPQFYAGRK
                     QDGRVAAKFLRKVGLFGARYSHTPTADGLHFVMRVIPDDGDVVPTLEKLGFLPKQIRL
                     IKRTLRLPEGMIILSGPTGAGKSTTLRACSDLYLKRTRYKKRLLTVEDPPEGRIVGAI
                     QTPIICDKADEAEVRLAWQRVLTSALRLDPDAILPGELRDLISILAGIFAAQTGHLVL
                     STLHSNSAFSIPERMITMGANAGLVADAQLLVGLISQRLVQVLCPECRIPWSVKKEHL
                     TTEEREYLEKYCSVEGVCQPENLHFRNEEGCPTCRKAVIIGGKQVATVGKGVAGRSVV
                     AEVVRTDSTLFRLLLQQGKEAAKAYWIREMGGITRRIHLLHKLNDGLVDPLDADLIIP
                     LDEDEVMQVVSDQVASSSDIDTSLIERLAMVIAASVREGMKQGVEEAIKEGVAAGMAA
                     LKEVA"
     gene            complement(30010..30597)
                     /gene="pilP"
                     /locus_tag="OPY25_000871"
     CDS             complement(30010..30597)
                     /gene="pilP"
                     /locus_tag="OPY25_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilP"
                     /protein_id="HCS0926549.1"
                     /translation="MLMPKNSVFISGVLLMAFSAGAFSQPTLAVPPSAEVISAMPASE
                     PATEAAASISSADLSDTVPIFPGNSVTAGQLEALQGKNLLLEAKVQAARLLKELTSAQ
                     TPGDVGNVPTTSPFVMGMPAEMNATPVHTPPATGRITVLEVSGRGNALQATLSFPDGR
                     QSLVQTGSVIPGTSLKVKAITLSSVTLSDGQQLTF"
     gene            complement(30578..31864)
                     /gene="pilO2"
                     /locus_tag="OPY25_000872"
     CDS             complement(30578..31864)
                     /gene="pilO2"
                     /locus_tag="OPY25_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4b pilus protein PilO2"
                     /protein_id="HCS0926550.1"
                     /translation="MADIPLSGKPRTQVLRWQRQNWVAGLRWEEKQKSVRRAPVQRRG
                     VLNVVLTVKQGKSRLTALGQIEAGWRHQKLYSLAALFSQQCTPNGYGVYQLDDGRQVF
                     LATVKGMPSPMADVIGTPDQIIRARELFLSFNPAPEDGWTIPSSPEFPLSWNTLVGQV
                     SSAQLRFARVAGVSNPLRPYGAGVLSVAALLGGAVWWSRLPEPPVAPVVQELPAPVQD
                     VFKKTPEPVYLPHPWADMPVARHFLNRCQRWRAAVPVSLDRWRLERIRCSAEGLETVY
                     QRQPGGTAAGFAERVKQVFKRTPVFNLVSGGNEGVVFIPWAKFTLQDETAPDAGTQLM
                     QAVSWFQSRQVSFSLSEVKTPPAMPGDGAGNDAPQPIQDWHEYTFSITDKHMPEWILQ
                     GLDMQGVRLSSVGYTLSPQGQFTYQIEGHLYAYAKK"
     gene            complement(31866..33162)
                     /locus_tag="OPY25_000873"
                     /pseudo
     CDS             complement(31866..33162)
                     /locus_tag="OPY25_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PilN family type IVB pilus formation outer
                     membrane protein"
     gene            complement(33576..33995)
                     /gene="pilM"
                     /locus_tag="OPY25_000874"
     CDS             complement(33576..33995)
                     /gene="pilM"
                     /locus_tag="OPY25_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="HCS0926551.1"
                     /translation="MGWFIVALGTVFLLVVGHVQTTQRSEVVKAQQSGSSYLLARQML
                     LLAAGINDWRYRHTLTDGTVALSELALPVAPDSRIRHVIVANRLWVWMPEVPGLVDAL
                     REQSGGSALTGTVTQGQLVWLSGIGNGPFSARVVPDD"
     gene            complement(33998..35242)
                     /locus_tag="OPY25_000875"
     CDS             complement(33998..35242)
                     /locus_tag="OPY25_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpQ domain-containing protein"
                     /protein_id="HCS0926552.1"
                     /translation="MNTQALFCLSLPLVIAGCAQQTSTQTARDSAFAQSQQPSVFSDI
                     YQRSPEVTRSGRYTLVSIKSADAQREPLNQLIDITMPGQLVNSVGDGFRYLLFQSGYS
                     LCGHYGADFSELLNRPLPAVQRKIGPMRLSEALQVVAGPAWRMSVDEVNREVCFVLRD
                     AYRVQAKTKALTSVTPAVTGAARTSSPETTRNPYTGVLPGNKAEPVIAGQHLAAKKGT
                     ELKPVSQSLPVPALRPGGTPVTSGVSSAPPVKQVSSPAPRNPFTGKNLTGTTLSASHS
                     PAPVGEKAQAKTPSPSTVKAVNPATATVLATTTKPLTGTPVAAVASGPEWKAVVGSTL
                     KESLTDWAGRADCPGGGHWVVIWQTPTDYRIDAPLVFKGNFETALVQVFDLYKKADKP
                     LFAEASRLQCLVSVADKPADRS"
     gene            complement(35407..36357)
                     /locus_tag="OPY25_000876"
                     /pseudo
     CDS             complement(35407..36357)
                     /locus_tag="OPY25_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(36423..36959)
                     /locus_tag="OPY25_000877"
     CDS             complement(36423..36959)
                     /locus_tag="OPY25_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCS0926553.1"
                     /translation="MASKGVNKVILVGNLGQDPEVRYMPNGGAVVNLSLATSDTWTDK
                     QTGDKKERTEWHRVVLYGKLAEIASEYLRKGSQVYIEGALRTRKWTDQSGVEKYTTEV
                     VVSQSGTMQMLGGRNSAGSGQQQGGWGQPQQPAAPSHSGMPPQQHPANEPPMDFDDDI
                     PFAPFGHSVARHALYVLS"
     gene            complement(36972..37190)
                     /locus_tag="OPY25_000878"
     CDS             complement(36972..37190)
                     /locus_tag="OPY25_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926554.1"
                     /translation="MLTSPSSSTGLLAAKFAGLSLPLQVLRSGAGYYIGTQNEEGPVS
                     RESVEYFSTQSQAEHALKQGTWSQREQA"
     gene            complement(37271..37720)
                     /locus_tag="OPY25_000879"
     CDS             complement(37271..37720)
                     /locus_tag="OPY25_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3577 domain-containing protein"
                     /protein_id="HCS0926555.1"
                     /translation="MSKETNYFNLNINGLGYITNVRQVVNGNSKFTCCTLNALSGPTD
                     NADYTRFDVTVAGKDATSLINRCQKSCDEDKKVMIGFVLSGIKSDIFTLAKGDHAGEN
                     RVSLKTRLIRVDWIKIDGAIVYKAEKPDSTPPAQSQPAQKQYAEDSF"
     gene            complement(38388..40382)
                     /gene="topB"
                     /locus_tag="OPY25_000880"
     CDS             complement(38388..40382)
                     /gene="topB"
                     /locus_tag="OPY25_000880"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCS0926556.1"
                     /translation="MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLL
                     ETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATD
                     ADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGR
                     SRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFE
                     VIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERK
                     KQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMRE
                     EIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDA
                     ERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSED
                     DEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAAL
                     KKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGL
                     TALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKT
                     LQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA"
     gene            complement(40493..41269)
                     /locus_tag="OPY25_000881"
     CDS             complement(40493..41269)
                     /locus_tag="OPY25_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03761 family integrating conjugative element
                     protein"
                     /protein_id="HCS0926557.1"
                     /translation="MSEKEQVSVSRKAGALRSALNIALNTDYAINLWQGRPPEEEGEK
                     EGKKKERRQSLIFSMPAFIQKAGRINADSFNDNPYADQKMLELETLLQSASVKMNEEL
                     VALKKSMSMLPPQATISEVNCASPLNIGVFSRTPLGYRCVWLLVGFDQLAMQAFQAAH
                     YGFISRQELHRSLRRGGHLIRQIYGAAQKYRFFQVNRRDFALQNAQYHEAIRNAGEID
                     EAVLLGQKRSSFSPPVSKESIELLLAANAKADKADIVQLL"
     gene            complement(41858..43168)
                     /locus_tag="OPY25_000882"
     CDS             complement(41858..43168)
                     /locus_tag="OPY25_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0926558.1"
                     /translation="MQTPAQVMEEPGSSVHRLPADDIIDYTLSKMQARLDGTPGSSGQ
                     ERNGLLFTGNIHDAYPRALILDMRLSPLDKMCWIMIRQYALQNDGAIFPSYDELQKLL
                     SSPGSGQASRDTVSRALTMLRLTGWLSLCKRVRDTGGRVRGNIYAQHDEPVSAKDAEM
                     FDPGWLDMVGKACQHKYREVSDTAFHVLNGILDDPMMRHRHSRMTEIAERLTRPSKVG
                     DVARTHQNPGTGLSLNSIKNEHKSLSPVNRPSSERGEKSPSPDSRLSLKSDSYDRVRQ
                     PDCNNVRSFTQSVIKKTYVSPQSGKNAVAGIPEGFVWPDGLQSILPESEQPMLAQQLN
                     QLAQKSPVQAEQIALSVVNGWHQKRISNPVGYLLTTLRQARAGLYRLEPAVTQPVKSR
                     SVVPAEPSAAGKIPTCSAEADVPAGQEVVKAMVEQIRQRMNSSQ"
     gene            complement(43198..43446)
                     /locus_tag="OPY25_000883"
     CDS             complement(43198..43446)
                     /locus_tag="OPY25_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926559.1"
                     /translation="MDSLAPSFQFYRTDPRNVSKAVTSKARTLLSLYQQGKRVYSQIG
                     QTGYLKIDLGLRWRLLSKDAGKSWLFMSHQTYNRELKR"
     gene            complement(43450..44004)
                     /locus_tag="OPY25_000884"
                     /pseudo
     CDS             complement(43450..44004)
                     /locus_tag="OPY25_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144323.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2857 domain-containing protein"
     gene            complement(44089..44811)
                     /locus_tag="OPY25_000885"
     CDS             complement(44089..44811)
                     /locus_tag="OPY25_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HCS0926560.1"
                     /translation="MSANEKVLSRIKKLMVLAEKTGNPYEASVALRQAQALMMKYDVT
                     PASVVPGEITSETCRNIPSNALSVPGWLNALVTVVCMTAGCRSYYGWYQNSDHKKRRS
                     VTFYGLGERPAVAGYLFGVVSRQLKRDAEHYLHTACAHPLLKLSTIRRRMDEYRLYWV
                     AGVWTVLESFEPETSEKVLLDRWLTQQQRNLTPAKVRQPEGCRNAKKVRQAAWTAGRQ
                     AEIYPAMDYRSEEHSLQEVSNG"
     gene            complement(44798..45058)
                     /locus_tag="OPY25_000886"
     CDS             complement(44798..45058)
                     /locus_tag="OPY25_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926561.1"
                     /translation="MKSLKKPRSHYQWVGATVVTTQELSSGLAVIPVGSRGVVNAAKR
                     GLSVIFDACPCCGVQLRLTRIRPEMLDIVAYPEIEEVTRVGE"
     gene            complement(45055..45282)
                     /locus_tag="OPY25_000887"
     CDS             complement(45055..45282)
                     /locus_tag="OPY25_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HCS0926562.1"
                     /translation="MSIDVDDSMAQNESQVNIDNRFAEIRAALRIKGHVSRRHCRDCG
                     DEIPDSRRESIPGVSLCMYCQEWRESGDKKQ"
     gene            complement(45272..47071)
                     /locus_tag="OPY25_000888"
     CDS             complement(45272..47071)
                     /locus_tag="OPY25_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB family protein"
                     /protein_id="HCS0926563.1"
                     /translation="MAKAPLLNLNNALLQGAKESSAATTAAVAIMPTSEMPMVLTLDE
                     VAPNPDNPRTTRNPKYDEIKESIRARGLDTVPKVTKNPDIPGSPYIFSDGGNTRYAIL
                     RELFAETQDERFYRFHALFKPWPGRLECLVGHLAENDVRGDLTFIDKALGIKKARAIH
                     EETLGRTVTLRELADLLGQQGYPIHNSMISRMEHTVEYLYPFMPELLVSGLGKPQIVN
                     LLNLRADALKIWQQYSVMTETDSDFNEIFGHVCTQFDDPEVYSFEMFRDEFIGMLVNV
                     LPHPSLNYDRWLLELDPKARNQRKLFGEPEPVASHLVDADRQTWQSTASLPGTANDEN
                     QQGGSSLKPKLNNAPVLPKQPDPDNDNGDNDDVTGEWFGSCGSPRLPKAEVQNDFLGG
                     PSVLTGDVIPDEYHFIPDAGNIAVSASAFAGAQVGLTADTPSDAVSIASEMPGLSLLP
                     TEPALSSVEFANVGLEPVTDIWVIPALQDDIEHLQDMAYRLAYELAEAMGCEVHVSED
                     KNASAAGFSVSEHGGEFALFLAGLSGHVPNKQFNMFMFCLNFFGSQSAGDTPVFDDVH
                     VVKSLRLIRVIRRLRELQRNMAAEQNDGRRHEH"
     gene            complement(47064..48428)
                     /gene="dnaB"
                     /locus_tag="OPY25_000889"
     CDS             complement(47064..48428)
                     /gene="dnaB"
                     /locus_tag="OPY25_000889"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCS0926564.1"
                     /translation="MSHKSVSAVSMLFNVGAETGVLGGLMLDNDRWDEIAPLLNSGDF
                     YYGQHQIIFREIERLVSAGLPIDLITLSESMERKDLLERCGGVAYLAELSKNTPSAAN
                     IVAYAEIVREYSRKRRLVKLGHELHQLASVGDADIPGLIEKAEKQLFSLAQQACDPDI
                     CLSVTTQVADTVSWLESVSGGSGVTGTATGFAELDEKTCGWQDGDLILLGARPSMGKT
                     AEALKHAVAALEGSPGKTVQFYSIEMPTQQLIMRLLSMLARVPFDNLRKGLLSEGQWS
                     LLADAVAKLTSWEGRLLIDDTSYQTPSTLRISARRNVRKYGQPSLILVDYLQLMSCPG
                     RENRTQEIQEISRSLKSLAKEIRCPVAALSQLNRSVEQRQDKRPMVSDLRDSGSLEQD
                     ADVIMFLYRDEVYNEHSPDRGIAEIILGKQRQGPLGTVKVRFEGEYMRFSEYHLGYGE
                     VSYG"
     gene            complement(48425..49375)
                     /locus_tag="OPY25_000890"
     CDS             complement(48425..49375)
                     /locus_tag="OPY25_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCS0926565.1"
                     /translation="MAQQVSPHSLLLPDEQQFPVVLPVVSTKGGEGKSTKAGNIAGYT
                     ADAGLKTLLIDGDYNQPTASSIFKLHYEAPCGLYELLMQTADLNKPDSIISRTVIPNL
                     DVIISNDPDDRLSNDMLHAADGRMRLRNVLQHPLFRQYDVIIVDSKGAGGVMVELVVL
                     AATQSVMGVIKPILPDVREFLRGTVRLLSKLLVLEPYGIHIPDIRILANCVEPTVLDR
                     NTLNELKAIVDKGQYPQSDRIAISMLNTEIEQLEVYKRGHACGQPVHRLEYKTDRVSL
                     PAAESMHHLVCELFPQWKDKFDAVLVNRPQPGFGQGADEV"
     gene            complement(49673..49747)
                     /locus_tag="OPY25_000891"
                     /pseudo
     CDS             complement(49673..49747)
                     /locus_tag="OPY25_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003842122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            50304..51056
                     /locus_tag="OPY25_000892"
     CDS             50304..51056
                     /locus_tag="OPY25_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-specific acid phosphatase"
                     /protein_id="HCS0926566.1"
                     /translation="MKSRYLLFFLPLIVAKYTSAATMQPFHSPEESVNSQFYLPPPPG
                     NDDPAFRYDKEAYFKGYAIKGSPRWKQAAEDADISVENIARIFSPVVGAKINPKDTPE
                     TWNMLQNLLKMGGYYATASAKKYYMRTRPFVLFNHSTCRPEDENTLRKDGSYPSGHTA
                     YSTLLALVLSQARPERAQELARRGWEFGQSRVICGAHWQSDVDAGRYVGAVEFARLQT
                     IPAFQKSLAKVREELNDKNNLLSKEERPELNY"
     gene            complement(51297..51788)
                     /locus_tag="OPY25_000893"
     CDS             complement(51297..51788)
                     /locus_tag="OPY25_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0926567.1"
                     /translation="MISTPEPLHAGHILTPFCCGVDSIDNWLKQRAMKNQTTGASRTF
                     VCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDPIPVVVLGRLAVDKSLHGQGVAR
                     ALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQWVGFVPSPMDPMMLMVTLGDLV
                     ESV"
     gene            complement(51785..52078)
                     /locus_tag="OPY25_000894"
     CDS             complement(51785..52078)
                     /locus_tag="OPY25_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCS0926568.1"
                     /translation="MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEA
                     ARAAAEEVLIEQRIIMADPEAYQEFLVRLDQTPSPNAALRKTMQTPAPWEQEK"
BASE COUNT        13285 a        14353 c        12043 g        12745 t
ORIGIN      
        1 ggttatgtgt agaagtattt acaggtttag tgtaatttca tctttaatat ttcctcttgt
       61 ggttttcaat gtctcagcct ctccttgttt cagtgataat tctgtgacaa aaggcacaca
      121 aatgatttca aagttacccc gcgacaagga ttgtaatgat tcagattcaa gttcacgtaa
      181 atcagtaagt gaaaaaatca tagagtccat cgccgagaaa cagaagataa atcaagaaat
      241 tatgaaaata gatcttgaaa tagagttgtt acgaacgaaa aaagggaaca tgaccgcaca
      301 ggattatgat agtaaaatgc gtgagctgac aaataaacat tcggctttaa aaagaaaaat
      361 ttaataattt actaaacaaa actaaatctc ctggttggtg gtgctaatga ctcggtaatc
      421 tgtaaacacc ccactcagga gttacaaatt tatgtccatt ctttcttcgg ccaacaattg
      481 ttaaaccaat caaaaacccc acattgatcg tcacaatgaa cttgatgttt tcttcgctag
      541 ttgagatgct taaattatga agatacacac attcaggagc acagcaaatg aacgcacaag
      601 cacgcggtgc ccgggccgca aggctttata aaagggctaa gtcaaagctg atttcactcg
      661 accatttctg tgttcaaaaa gccagagagc ataagctgcc cgcctggact ggtcatctcc
      721 cggtgacaac cctgacaggg attctttttg ctgcagtgat ttttggctca ctgttatttg
      781 tgagcttagg cttatttata tttgcactta ttctggttac atcgtggcct ggaaaaagaa
      841 caaactctgc ggactcgtgg agcgataact cttggggaag ctcaatgaga gatggaagcg
      901 agggatttgg tctatacact ggcccagaaa atagccatat actaacaagt aggatagata
      961 atgaggatga cctatgaaag cactgtaata tttacagtgc tttcacgatt tcttatttag
     1021 ctattcccga gccaatttta tcaccaactt tgccaccatg ctgtccagct ggctgcactc
     1081 ccttatttaa gttagtgtca acaatgccgc caattctaac cccagcccag gaaagcgccc
     1141 ccatccacac tgccggcaac accaggaaca tcgtccccat aacaaagttc atgatcaggt
     1201 catctgcgct attctgaaaa ccggccacat tccatcggct atggctgtcc gaaccataca
     1261 tgatctccag aagccagcta tccagccagc gcgccagctc ccaccagaac gtaagaaaat
     1321 gcatcccaaa cgtcacaaaa gtgagagtga ctactgtctt atattcatac gtcccgaata
     1381 ccagcaccag ggggattagt acatacatgg ccatcaataa aagtgcctga accatcggta
     1441 acgcctggcg catggcatca aatgcgggga acgccccaag ggcacccaca ctggtcccca
     1501 gcactgaagc catgcgattt acagcattat ctaacgtaaa atcggcatta ccgccataac
     1561 ctgcataagt acgtccattc tgtgacacag agagacttgt cggactgacc agacgtcgaa
     1621 ttagcgcttc cgtgtattcc tctttgctga ccattccctt aaatgctgcc gccatgcgtg
     1681 tcatcgtggt ggtatttacc gtatccagca cacgggattt caggcctgtc ttgttctgag
     1741 accaccactc gctacacgtt ggataccccc cctgcccggt atttgcgtac ccgtcatcgc
     1801 ggctttgcga ccaggggaac gctgacctgg gcaacttcga atgcagctgc gggtaaaaat
     1861 ccttcaaaaa tattttcgac cccagccatt caatatccct gagtacatca atatccgtag
     1921 ttctccccgc atcctgccgt ttccataacg caaaagcctg tgcataacag tcactggtaa
     1981 aatcctgcaa ttcctgagcc agagcaggat tggtgatctg cgtatgctga acgtcaaaac
     2041 gcacctgccg caggtctggc cggcagggta aacttgccac agccgcctga gtgacgcctt
     2101 tggaaatcat atgcataaat gcccaccaca ccggcgcaga tgcagtcata ccactcattg
     2161 ttgaaaccac actaccgtag cctgaatccc cgggcttgac cggtgtccag aaaccacact
     2221 gtttcgcacg ggttgtatca aacgtcagcg ttgtcagtga cactgtctga gtggggacac
     2281 agcaggcgat aataacgata aatgccccgt aaatagcatg ttccatccgt cgggccgaca
     2341 ggataccttt attaccctca tcatcccctt cttcccgtgt tttgatccag ataccaatga
     2401 ttttaaagcc cagtggtaat gcaaaaagtc ccgtgcctgt cagaacatcc cacaaaccgt
     2461 tattaacaac ccagcccaga atcgtcagga tgtactcaag atagctcgat gtcgtcatct
     2521 tctacctcaa cactgaatat tcgcaaatcg cgacgaaacc aacagaaacg acagcaatcc
     2581 gcagaagact ctgacgcaga gcctgagaag agccatggga gtgataacaa cgccatatcc
     2641 cccaaccagt cacgctgtaa agcatcagcc gccacagaag ccacaacaac caggtttcct
     2701 tcatccagat ccggaactgg gctatttcag actgataacg aaaccctaaa tcagccagtg
     2761 caagggacag gcacgtaagc ataaccagca tgaacacaag cgtcagaata aatctcagaa
     2821 atgaagttgt tttgattaag atcctcagtg tcattggctg tcccctggtt tacgcgtttc
     2881 aagctcactc agccgggtat cagcattagt ctgcgattct ttttgaggat tggtgaccga
     2941 acgattttct tcgcgcgcaa ccacaaccag cgcggtattt tttgccactt cccgacgcag
     3001 ttccatctcc agcttaagag agttaagctc acgatcgaga gcttcaatac ggcgatcggc
     3061 ttcagccatt gcctgaggct gatcagctgc attgggttca gactggccag tcgttaacat
     3121 gcgacgcatc gccagaccgg tttcaatcgt gtcggacatg gccagttcgc cagccagtct
     3181 ctgaaccaac gcaccggcat caggatcgcg tttcagggca tcgatgacac cacgcgttac
     3241 cttaaggctg ccacttttaa ttttatccag attggcctga gtcggagcct cagtaccatt
     3301 tacaagcttt accagctgtt ccagattctc tttggttgta tcctcaagca tgggagcaaa
     3361 accggtaccg gcaattgtcg tgccctgggc attatcaatc ccgccgcttc cgcattctgt
     3421 ggcatcttta caggtgcgaa tactccgatc gcccagaact tttacgaccg ctgctgcagc
     3481 ttcttcagag tttttaaatt tctggcatgc tgaccccttg caactaccgg cggataccgt
     3541 gctgttgctg gtaacgctca ggttattcat catgttgtat cctgctttag ccagatcacg
     3601 cgttggctga atggcaggct ggcctttccc tccggctttc ttcccgccta cccaggtagc
     3661 gccctcctta cctgaagctt tggttctggc ctcttctgcc cgcagcgcat ccccgccact
     3721 ggcactgacc gcctccttgt actcttccct cacagctgat tctgtccagc tgctcttgtc
     3781 acccaaagtg taatcagcca gcttgttggc catgctttca caattcagtt tcgatttgtc
     3841 aaaagccaga cctgcctgaa gtacaccatt ggtgatcatt tcatacaaac ccggatttgc
     3901 tcgctgaagg atcatcgccg gcatacttga gaccgccccg gtcgcaccgg tgatcacatc
     3961 ccccatcaaa tctttgaaac cattcgtgac gccattaagc tggtttccga cagtagtctt
     4021 tatatcaaag ttgccacaca tcaaatcact gctcagtccg gcatccagcc cgatacgttt
     4081 cattccgtac atcgtcccgg gagtggaaat caccgaacca ccaccaatgc tgtaaaacag
     4141 cttgtcacta accgcgccat ttactgactt tccatatcca tcaccactca acgtgggggc
     4201 atccagtaat gcagcactta acggtcccga actgacgata cccagcatga gacagacgga
     4261 taaaatggat tgagatctca ttttcgatac tccacttaat ttatgtcggt gctatagaga
     4321 aatgtttgcc cacggcgttt acagcagcta tatggctgcc agagtgtcca ggcgtaatta
     4381 ccgttttccg caatttttcc tgtatccggg aatacgctgc atgacataga gagcgttggt
     4441 gataactgct gccatttatg attttgcgtg ccggtattct ctttaacagg ttcgggaggc
     4501 cagtaaccgg cagacgggtt tccggtgagg ggcttataga cgtggatctg gttagttcgg
     4561 gtgataatgt cagctacacg ctgcgcaacg attgccccgg atttgtagtc atcctgctga
     4621 gtaacaaagc cgcttcgggg atagagattt ccccatatat tttgtgccga tgtggagccg
     4681 atttcgcgtc tgccaggaat gagtgcctca ggataaaccg attcaggaac accagtacgc
     4741 caggcaagcg tatcaagcgt gctaagaaaa tagggtacca gtggtgtggc ggcgctgttg
     4801 catgagtaac cggggatttg gccgccaata atcgatgttg aaggatggcc aatggcatct
     4861 gcatatttaa atcgcacatt actcttacgg gtacccggga atttctgttc ctggtttccg
     4921 ccaccggcag caagcccgga taacgccccc gttacagcat tctctacccc tccggccgtc
     4981 tgactcacta atgacatttc ggtccacgga tttccaccag acgcctgata agtcgaaaca
     5041 acagcttccg gaataaagtg atgcactttt atcgaggttt ttactgtaca accgaaaggg
     5101 gtacacatca gccagtagca gataccgctg attctccagc tgatacacga cggagaaata
     5161 ctgctggcca caatcgaggc agtgttcaac gcagcctgaa cctccatgcc gccggtgata
     5221 agcatgactg acagtaacgc tcgcttcaga cgaagagatt tcattgattc tctcccctgc
     5281 gcagcgccac tgcccgggat atatcaacag tcccgtaaac cacgtcacgg ttgtcaaaaa
     5341 ccaccgccgg atatttcagt aaaccaagct gccatgcttc aatcattccc ctgtaatgtt
     5401 cgataagcgc tttttgccgt ctcttccagt caggagaatt cagcagagaa tgagcctgtc
     5461 tgacagcctg ttcaggatca gaagaaagct ctccaaattg ttgctgcagc cagcgttcgc
     5521 tggcatcgag ataaacaacc cggatagccg gtgttacacc gaccggagga tgcccctggt
     5581 cggtgtaaac aacgatttgc gcacttgcag aaaaggagct gattaatatc agcgaagaga
     5641 ggattcgttt catgccacgc tcctgacgat aactatccgg atagcgtgcg aaaaacgcag
     5701 aggtaatgca gtaataaact ctgttttgct ttttaataat tccccgcttc agaatatgtg
     5761 gaagcggaat atgaaacgcc ggcttttacg ccggcgagtg tacctgtcta cctgataagc
     5821 cacagcgcca gataaagggc atctgcggca tcggcaacat cgatgtacca tcggggatta
     5881 acgtaacttt cctccgcagg taatgctgtc tttccgctta ccgtaattaa tatatccagc
     5941 ttttttccgc gtaaattctc aagatggatt gccaggcagg cacgatgccc gatacgctgt
     6001 ggatgacaaa ccccacgata agtattgcca agagctccct gaatatgaga agtcagacga
     6061 ctcatatcct catcatgttc cttgcggatc cacgctttac cctgcggagg caaacccagc
     6121 agcgcatcag gcggaatacg atgcgattca tcttcaccga gaattaacca ttgctcatgc
     6181 tttaacaggc tcataatccc cccattgaaa taccatcatt gagcaaaaga gatccttcac
     6241 gtccagcctc cccggacaac cactctgatg acataacaat gactcctctg atattggtaa
     6301 aactggtcac agggcttggc cattgcccgt ggctcaggaa ttgttttttc aggccgcttt
     6361 ttgtggacaa aaaccccgtg cctcatccag cctgcgggcc acccggatcg ctgcctcaag
     6421 ctcactgcac tgatactctc gcatcagccg ctgacgttcc gctttttcct ctttttcagt
     6481 catccccagg gcgagataca gactgggagg cacaacccgg aacagtgcct caacctgctt
     6541 tgataaaacg acgccctcgg tataacagtt tttgagctta ctggctgatc gcaaaataac
     6601 tttttgctcc tcgctgaggg ttttgaaacg ggcaatctgc tccacctcat cgggaggcat
     6661 aaccaggcac aaccaccatt cagccatgtt cagcattttc tgcgcaatat caggaaaatc
     6721 ctcgaggttc tgtgtcgcca gccacagcca tgcccccagt tttcgccaca ttttcacaac
     6781 cttggtcata tagggcgaca acaaaggatt cgtcgtggaa atatgggctt catcaaatac
     6841 ggccacaata tcccgggctg ttccctggtc acgttcggcg atattgttaa tcgtgttaat
     6901 taaagagacc atcgccagcg ccatttgtgc accatagcct tcacgtgcca gatgacctaa
     6961 atcgatcagt gtgacatcag cctctggcca tggtgttccc ggacggttga ataactctcc
     7021 ctcaaatccc tgagtgaaca tggccatggc ttctgccatc tcagcagcac gatcgcgacg
     7081 ggactgattc cgcataggct cgccatttgc accaatggaa ttatcacgtg agatattcca
     7141 cagggcagcc tgtaaatcct cagccagcat ctgatgtccg tcctgatatg ttttctccgc
     7201 cgccatcatg atagcttcac gaataagacc gcggtcagcc cgggtaagac gttcctcctc
     7261 ccgcttctcg ccaccggtga tcatcatccg ggctgcaatt tccatttcgc caagaatgtc
     7321 acgctcttca ctttcatctt ctgcgctgtc ggtattggct ggctccagct caggtagagc
     7381 ttcctcagaa accacgtttt tctttggatc tactcgcatt aaggaatgag catcagcaaa
     7441 catcggtaaa gaaataccgc agccaggttt gatactcagt acatttacgc tcagtcccag
     7501 cccccggaaa tactccgcca gcaaaccaaa actgttgccg gcttcggcaa taaagaggcg
     7561 tggacgatga acggccatta actgtgataa cgcactacat aaggtggctg atttacccgc
     7621 cccggtcgga ccaaaaagca acaggtgagc attctgcgtt ctgtccagac tatttaaggg
     7681 atcaaaagac aacagttctc cgccacggtt aaaaaaacta aacccggggt gtccggttcc
     7741 ctggctgcga ccggtcacgg gaagcaatcc agccagatgc tgaacccagg tcaggcgggt
     7801 ataccagttt tttttatcca gttgcgggtt aaaacacata ggaagcgctc gcaaatagtc
     7861 attcaggggc gccacttcgt attcaggttt cgtgggctgg agccccgcag tcagcaatgt
     7921 agcggtaagt tgctgtattt ttttattcag ctcactgaca tcaggtgcac gcatcaaaaa
     7981 agttatcgat gcacgataaa gtttgtgacg catgcccagc aaactcttca cctgctccac
     8041 atcactacgg gtccgcctgg attccgtgtt ctgccctatt gcatttttac ccagcgtgtc
     8101 aaacccggct tccagcgtgt cctgagcctg cgccacaata gtgagcgata ccattgtgcc
     8161 ctcaggcaat aaatccatca gagtattaat attgtcgcca cgcttaacct cccccgtcag
     8221 atgaccgggt cccggagggc gacgtaatgt ttcaacagga acggcacgat gcgccacatt
     8281 atcaaaccac cacacaccat ttcgggtatc agaacgtgga gggttaaacc acaacgtctc
     8341 agtgaaatca ttgccaagag gcaatgaatc aggtgcatca tcataataac gagcctcccg
     8401 gtaaagcgta tctttgtcta tccagtcggg ctcaggattg aagtgacgta acaaccatcg
     8461 atgtatctgc tcgccattct gtcggacact cagaacgccg gctgcagata aggctgaagt
     8521 caggcgctca caaacctggt tgagagcggc aaccggcgaa tcatctttgt aattcgctgg
     8581 caggtatcga tataccacca tcctgacgga acgattttgt ccccgccagg gaaccccggt
     8641 gacaagtgaa tcagtgaaca aaccttccgg ccgggtgata tttcgcagat gctgttctgt
     8701 ttcagccagc caggccttcg taaatgccgt cctctgagca tgcggtttga tgtaactggc
     8761 taaccgattc atataggcac tgaagtcagt ttcatcctga caaaaaactg tactacccat
     8821 gggttagaat caaactcttc aaggctgtcc tgaagtgcat cttcaaccga atcccttatt
     8881 tcttccagac gggcagctgt gcgcccctct gatgccactg gcgatatact gtataccgca
     8941 ccgacagact ggccatcgtc aagcagcaga cattgctcgc gactcaggta ctcggcccag
     9001 ggcaaaaaat caataatgga cggacgggtt tcgtataaac gggattcatc agcgtgactc
     9061 atcatgcccg ggcgtttcag tgggtcacgg ccatgaacag caaagtcact ttccggtaac
     9121 tcgtcaggct cccggggaga agatgacttc agcctgtttt tgttaaacaa agaaaaactg
     9181 accatcacag tgcctccgtc cgttcaccag gaagcgcata ctgggtttga gcataaaaag
     9241 gaaagacagt gctgtagcca ggaacaggcg tatttccatt agccaagtgc ggaaatatgt
     9301 acatcaccat atccggatta ggtaaccggg ggaaaatctg gctcagctca ttctcctgag
     9361 tacggctgta gctttcatca atacgccctg aagccagtgt ttcctgagac gaaagactcc
     9421 gcctgagagt ctcccgccct ttgacaacgg cgtgagatgt cggagcattc ccctgccaga
     9481 gctccatcat tgaactgtct cccggaggca ataattcatc tttgctggat gagcatccac
     9541 caagcgcgac actgaacatg cccgctataa aaaataaaac gggagttatt ttcactgtac
     9601 gtgaagtgat tttctgatta tcagtcaaga ccataatggc ctcctgttcc gggcaagctg
     9661 aagtcatatc gaaccttacg accatggtct tcataatcaa cggccagttg acgagtaata
     9721 tgaatagcga catttgcacc aggtgggaca tacaccgcat caaacgtctg tccgtaacgt
     9781 tgtttaaccc agtcggtaac ttctttaaat ccccctccca gcgtctgccc cagtaccgcc
     9841 tgccccgcat tgccggttaa ggctgatgtc accccaccat tcacattgtt ctgagtggta
     9901 tattgatttt gtgttaacgc atcacctgcg gagcttccca tccccagtaa cgcaaccgtt
     9961 ggcagataag ttgaagcatt agatttgcgc tcaccactga tacagggaat tccgttgtta
    10021 tctgatatcc agccaatgct gcccctgtct ccggcgttgt cattattgtt gccctgagtg
    10081 tttgctacgg gtctgggaag tgttcttata cgtccatcgg aaaaaacaaa cgtgatcgaa
    10141 tgtatcgttc ctctgacaca cgaaagcacc atatcccctg tagcagtccc ggaaacaata
    10201 gccccctcaa catcgggcaa ttcgataccg tttgcagtta ggttatcctt accgatcagg
    10261 actttaaatg gataaggatc ggtgactttg tcattaattg gtatacgacc aattaatgcc
    10321 gtcatcgcct tactgcctac cagggttgag ttctcaggca acgtataaac aggccgtgta
    10381 tcggactctg caccgtttcc gtccagttcc tgcttgtttt taacaacgcg atcgtactca
    10441 gctcgctgac gactgacggg gttatcatcc agaaaagagg tgggaaaggt gaatttatca
    10501 ttatcactct ggctttgacc ctctgtcttt ttagcatcct gaggagatat ccagatcacc
    10561 tccccctgag ttgcagagga tgcattctct ggatccagtc caaggccaac cgggaaatcg
    10621 gttcctgaag acgaacctgt cgacaccatg tcagtgtttt gtccctggga tttcagtgtt
    10681 ccggtcaggt cattgagctt ctccagtagg aacgttttct gtttttcaag agcctcgttc
    10741 gtttcctgtt ttgcggcatt tacagcattt gatatctgga gtcctaccga tgaattctca
    10801 cccttgagct tattattttc agaaatgagt gccttatttt gctcatccag cacagcctgg
    10861 cgggcccgga catcacgcaa cgctccaata agtgtacgta gcgtgtctgc tgacgtatcc
    10921 ccctcaatac ccagtgcttt caaatcatcc tggctcaact cagtcaatgc attagtggtt
    10981 ttagcgggtt caggttcagt agtatctttt aaaccacagg ctttaacgcc aataaaacaa
    11041 accaccacga tcaatactgg aagtaaaacc ttcatcaggc cattggcttt aatttgcatg
    11101 ctgttcccct ttttttactg ccggcaatac tgcaggttca gcaataaagg cattctcagg
    11161 gcgccctctg atcacaagat aaagagttgt tgtatcttca ggcgtaccag ccgccccaag
    11221 ccaacgatgc tggaaagtcg cactgacaaa cgatcctgat aaagtccggg catcaagtat
    11281 cactttggag gaagaacgat tccggatttt cagtgcaaca acattcagtt cctgaatacc
    11341 ccatgcccct attggcgaaa caactacatt ctcagacgga tataaagttg tgagtctcga
    11401 gggaaggcgt aaatttaccg gatgaattcc gggtacagct tcaacagtgc gtagaggggc
    11461 atacagactt tgtgcagcat aacgagtcaa caccactggc aatggagcac tgtacaccgg
    11521 cgtttttctg acagtctgat ttttatcttc tgtatccaaa gaggcgactg gcaacgaaga
    11581 acccgtttcc attccttttt cgctcaccga taacacttct cccgaataaa ccaggcgaac
    11641 aggctcaagc gccttattgt catttttggc agcaatatcc agtaatataa tctcgcccga
    11701 ttcaacatcc tgcagttgaa gtcgggtctg ttcaaaaggt tcgctggcct gtaaataaac
    11761 cgtaccaccg ctgctttgaa ccctcagttt acctttgagc attgccggaa aacctacacg
    11821 aacgttgcgg tcgacaaaga caattcgctc atggttaaca gaaagtggaa taagcagagg
    11881 gatccgttcc catttcatca gctccacagc ctgtgctgat gaaaaccata aaaggagaat
    11941 tatcggccac catttacact taaaattaag gactttaaac atcgccatta aaacatcccc
    12001 tttttctctg gctcagggac cactgcagct tcaagtcgtt gtgggacgcc tttatagcaa
    12061 tcaagcgcca gaccaaaagc attgcgctcc ggatcacctt cccagcggac aatatgcagg
    12121 gggtatctgg ccagtgcccg ttttacaggt tctgtgtgat agtattcatc gactaccaaa
    12181 tccagactga cctcccaact gtcatcgctc tcaatgatga cactttcagg tttgtaacca
    12241 cgtttgggga tctcataaac gacgcgaacg cgatcaagca actcaccttt ttgactccgt
    12301 agctcagcat ccttattcaa aaaatcctgg catgatggcg taagataagg actcaactgg
    12361 gcaattttca tcggatagtc tttttctccg tccttcggcc aggcattaat ttgctgaaaa
    12421 atataaaagg caaagctgta gaccgtactc ggagggacct cccaccattt acgcgtactc
    12481 ccgctgcgta aatctggcgg gttatgtatt gtcaggtcac tgggcgcccg catccatcct
    12541 gtaataacca gaatcaataa gagaagcaga actccacacg ctaatctcag ggtcaaaata
    12601 tgctgatcgc gatccttcag agcatggcga aatcggctca tattcccccc ttgcgtacag
    12661 gcttactcct gcgtaatgac cagcgtcgat catgacggac cagaactttg ctcccgatac
    12721 caatatggct cagtattttt tgaatccgga ggtagaggta aaaattgggt ttattacgtt
    12781 taaaacgaac cagaaagcgt ccaccgataa aaataaatat cagtggagtg ataagagtac
    12841 aggttggaat aattggccag ccgatccccg ttacaagcat cattatcaga gacaaaatta
    12901 agcctgacac ggcaccaata agtgctgcat agcccagttc tggtgttgta aaccctctga
    12961 aaactaccgt ttcggcattc agcctgtccg gtaaaaactc gattgttttc atgaggccac
    13021 ctcaattcaa aatcttcgcg gcttcagtac acaaccagac aatgacaacg agaatggcta
    13081 taccgacaac gacaatcgca acaaatttac cccattctgc tttaccggag cgtatttctg
    13141 agaatgtcgc cagaatagcg ccggaaacca tataaaatcc gacagcacaa atgattagcc
    13201 ccatcaggac gagaaaccca gaaaacagaa gcttgatcgt ttgcatcatg tcacccccac
    13261 cgcccccacc gggaatattg accgtaggta atcctgcatg agaggagaag ctcgccacca
    13321 gtaacagcag aatcaaaaga cagggaagtg gtactcttaa cccatgttta ctctttgaaa
    13381 gcatcatgtt ttccttttaa ccaaacaaat tattcagctg gcgaacatcc atactgaaaa
    13441 cacaaccaaa atggccgtac tgataaaaaa atggagagca ttttgctcag tgacttttcc
    13501 tgcccgccat ccacgaaaca caactaatac cgaccaggca aaccacaaaa aaagaacgct
    13561 cagaacaaaa cccagaacaa acttattaag taccgtaggg tcgatacctg accctgcttt
    13621 aaaagcgttt gcctgttcag aattcatagc catcagggct gctccttcct gtattgtcca
    13681 acaagagaac ctttgtctct tggctgtgcc cgggaaggct ccagataagt ttcaatcccc
    13741 tgcttcatgg ttttcaaatc acgtgttgcc cgctcatagt cgaagaagaa acgcccgtca
    13801 gaattgtcct gtaccgctac aattttcgcg cgttcaagcg cagactggac ctggtccagc
    13861 tgcctgagag cgagggccag ttcatccttt tcagctgcac tgaccatctc tggcagagag
    13921 aacaaactga ggacgagtaa aaacccttaa aggtctggaa gataattgac atctttgcat
    13981 taccacctct gtttcatgga gtacgtctgt cacaacagag tggcgaaatc agggaggaga
    14041 tgcagcagga aactctttat gcttttttga aatttatatc ctcccggggg gctggtgcca
    14101 gccccccaga gaagacaata agtcagcggt tgaccctggc cggtcacaga tattttttga
    14161 atgtagatgt cactacagta accgccagtc ccagtaacaa tgccccgggc agaagtaaca
    14221 gatttggata aatcgacgca ggccatgaca agtaaagtaa gcaagggaga taaacagccg
    14281 gtttaacaaa ccgtttggca tggtgataca gaaaactcga ctcataaccc gccccgtaac
    14341 gtctcaggtc acgacgacac aacccgtcta taacagcgac gatgataacc agaacaaata
    14401 acgggatgga taaaacaaga attaataccc tgacggcaaa aacgacggtg acataaacca
    14461 gcgcaagcag ataatcgctt aacactgata ataaccaggc ctgcacttgt cccagaaaaa
    14521 aaacaacaga gtcagaactg cttaatgtct ccctttgttc tttctgaatc caggtgagta
    14581 atccactgtc cacaaatgcc cattggtaag ctgacgaaat ccagcccatc gtagttactg
    14641 atggtgaaga aaaaataagg ctttgagtaa aatctgctga taaatagcca agttctttat
    14701 tcataacgga ctgggaatgc aaagctccct gatctgacca gaaaaaaaac attcctgccc
    14761 attcaataaa aacaccagcc atccaggata ccagcagaaa agccaaaagc ctgactggcc
    14821 agatccacaa aacaagggtc agcaaacctg gtggcttgcg cggtggtgga gaactttgag
    14881 agctgttttt ttctgtactc atagcgcatc caccagatta tctccgggga gcacactccc
    14941 tgaccaccag gtgtctcccg ttcggtagtg tttacgcatt gtagtgacaa tactctgcag
    15001 gtttaccggc atcatttcat catcaacgga tgccggcagc ggcatacgaa tcttccataa
    15061 tcgccctcct tccagcagtg caaaagcctg ccctttaggt aaattcatta cttctgcagg
    15121 agataaaaga ggaacacgtg tactgcttac tctgtcctga acgttggatg tgaaatcact
    15181 cccctgatcc ggattggata tatctgtcac accggaaacc agtgtttttg tataaatttc
    15241 aacttcaggt aattgcgttg tcagcaactc agctgtcgtt ttctctctca cacgaagcat
    15301 aatcatatta ttgaaattgc ctgtgacctg ggcagcttta gctgcattac caattttggc
    15361 ctcaatatct gaccaggtct gggtataggc tgtaacttca atacctgccc caccgccttt
    15421 atttatcatc ggaatgaatt cttctcccat taactcattg aattcatcac agtgaagact
    15481 gatgggtaac cgctggctac tcccttcggg catatcatca gacagtccga acttataaat
    15541 atatccagct gttgaaacca gatcggcaaa catactgtta cctaccgcag aagcaacttc
    15601 agaatctgaa agagcatcaa gaccgacgta aacaacaccg cctttccgta taatttcctg
    15661 ccagtctatt aatgggcgcg gatcattcat atcactgtag tcaggagata atagtgccgc
    15721 agttttgcct gtggtcagtt tttccagaag aggtaacaat gaagcgacta ttttatcgaa
    15781 atatgttcga tcataacgta cagcgctacg caacccatcc agtacgggat cgtatatttt
    15841 tttgccctgc tcactggata atgccacttc aatggccata acccgaatag cattaacctg
    15901 tccctgcatc gtacgtggta aatcatcctc agtcaggatc cccatctggt tttgaaccat
    15961 cagccacaac tccggagcct gttgagtcag taacttctcg gcataggtct cataaagctc
    16021 tgcaatattt gttacgtacc ggaggataag cgaataatca ggtcgcaaac caagaacgac
    16081 aagagcacga gcgatgatat tgacaaagcg ccatgcaaac tctttaaacg cagcgttatt
    16141 tccttctccc ccaagctgcc cggcaacacg tgaggccact tcagatacgc gtccaaaacg
    16201 gccgactgca ttataacggg cactgatatc tggccagcca agatgaaaga tataaaactc
    16261 gtcgctacgc ccagctcgcc tcgtctcagc ccacattcgt ttcaacagat cagcatcacc
    16321 tttggggtca aaaacgatag tgacatttcc tctgcgaata tcctgcgtaa ttaacagttc
    16381 tgccagacgg gtcttaccaa ctcgtgtcgt tcctaataca agaagatgtc caacgcgctc
    16441 ggtaagactc atcaaaacat tatcttcctc catctcgaca ccatgtatcg ccgaattacc
    16501 accaacaggg ggtaatgggc gtaccggatt aaaaaatgaa tctcgtcttg tcaggctaca
    16561 taacccaggg aatgtatact cataccgtcg ttcaaactga cgagccaggg agtaaaaaac
    16621 tgacggtttc agaaagggag caacttccgg ccgtttcgtc tcaagcaaac gttgggtatg
    16681 cttttgctcc cacataaagc ctttccccag aaacaaaaaa tgtcggctta ccggtatgga
    16741 ttcactggac atctgatacc ggggtaaccg acggatattg cgtcgatagc gcaagatgcg
    16801 caaaccctga cgagttctga ttgttgtgaa aatggcaaaa ccggctgcag tcacataact
    16861 gacctgtggt gctaacgcca tcgaccatgg tgcgacaacc agaacaaaag tggcagcccc
    16921 gccagccgca gctgaataga gttctactgc tggcctcaat aacgcctcca tgacataacg
    16981 gttactcata gctcctcctt tcacactgtt atgtaacaac cggctgcccg gcaactgact
    17041 ttgttactgg ccggtggtac cagcactggc gccccgccag caaatcaagt agtcgctgcc
    17101 cgctgatcag ttgtattgtt cgccagcact gcaggtaatt aacgctctta ctacccgtcc
    17161 gccctgtatg aataaaaaat ccacaacatt gctcccgggt aatcagctct ccgaactcac
    17221 gtatatgctg cggagaaata gtccgtctgt agcgttttgc ctgaattaac cagcgctttc
    17281 cgtcaataaa aacctgcccg tcaagtccgc catcgctact gtaggtctgg tttctcacaa
    17341 ccaggagtcc ctgcctctca aacgccaaca acagcagctc ttcaaacaca tacgggttaa
    17401 tttttcgaag atactttaga cgggccccgt ctgaatcaag cgctgtcaga cggcacagca
    17461 cacgctccgc gttctgtcgg tagcgccggt gccggcggtc gcgtgcggac ggcattttct
    17521 tacgccatat ggcaggaatg agaagacaga aaagtaaaag aagaatggca gtgatcatga
    17581 gagcacccta ctgggccaga ccggtggcgg taatcaacac cgggtagtgg ttgagatgca
    17641 aacgacgcgc tatttcgctt gccgatgccg gtagcagaat gacatcaggt atgatttgct
    17701 gaagttccga caacgcgtcc ttatcgctga cattcaccac cagacctgta gcatgaagtc
    17761 gcttaagctc atcacgccgc atcgtcaacc actcgcgtga aagcgaatca tccccaacaa
    17821 gaaagaccgg tgtcatcccg ttcagattta actcacgggc ttccactttc cctgcacgca
    17881 tttccggtgt ggttacgggc agcatatcac ttacatccgc aggggctgcg gttacagacg
    17941 cgcccgtggc gttcagtgac ctcggcggag tgaactcgtt gttcttatta ttgatggcat
    18001 caaaaagcgg cgctgttggt tctccgccaa gatcagcaat cacattgagt gctgccatcg
    18061 atgatgttgt cagcaaaata ctgaccatta atgtcctgaa aaaaaaacag acagaataaa
    18121 gtttcactga cgggactccc tgggttcaac ccattgcaat tcacggttgt agtgtgagaa
    18181 atggcgctgt gatggcgata tctgtgcgat ctgaagttcg gagtacgtta ctggcgcgtt
    18241 taaatccagt gttgccagct tgcgtttcac gatggactta tagattcgtg ctggttttcc
    18301 acctgcagga tggtgataac accccgcggc ctgtatccag cttcccggat tgttgtcata
    18361 acaggattta agaatacggg cggcaacccg aaggttggta tatggatcca gcgcttcgta
    18421 gtaactgctg aaataagttc cattccagcc caggttaacc tgcgcgatcc caacatcaat
    18481 ccgctttaac ggatagcgac gcatgaacga caacattgcg tcatacgctt cctggcggga
    18541 gttataccga taccctttcc cggcaacatt gagtgtccac ggccacggtc gctctccatg
    18601 tggtagtttt cgggatgttt ctgcaagaga aactgaatac agggcttcag cgggtacgcc
    18661 gacttcagtt gccacaaggt ggtaacccgg gggaattgtt tgcagaccgc gtcccttttc
    18721 taccgcagct gcactaccaa cacccccgat aagaaggatc agaacaggga cgctgtatct
    18781 ggctgctgtc agaatgctgc gatttgccat ccggagactc cctgctgaag cataaccggc
    18841 atatatccct gaccatactt cagccagttg ccgttatcgt ggttgagggt tatctgccgg
    18901 ctacgaactt tatcgaccgg aatatgatgt gcaagcgccc actggcgaat ggtgtcatca
    18961 ctgccgccac tgtcgaccag gtaaatatca accggacggt tatctgccag aaccgcactt
    19021 actctggcat cgcacggtac acagttgcgc ttcacaaata acgccagtct tccctgtgta
    19081 tcatgggcaa taccgctggc attgcccatg tttacggaga gagtattggg ataaaggcgt
    19141 ttccaggcag catccacttc ccgctgaaag gccagctcct tttcaccccg ggcatactct
    19201 tccttcaccc acatttcagc aaaacgccgg cgttcgcttg ccgaaccggc ctccagcccc
    19261 agtgccatca acgggtcaat gccaggtgac tgaaatgctc tgggaccttt aagtacctgt
    19321 tgatactgct gccattcttt ttcgctgagt ccccatgccg ttcctgacgt ttgcgtcctt
    19381 ccttctgtag tcgtattttg ctgctggggt gcgcttacac tgcgacccgt actcactgat
    19441 gcaagagcag gcagacttac gataacagcc agcatgactg acgcagtcca ctgccggagg
    19501 caatttaacg ttgatttcat cggtttcatc caatatttct ccctgattca gagcgttaaa
    19561 cgttgtacct gcccgttaac ctgaaactca gcctggttac cgctgatgtt caccagcacc
    19621 cagcctgaca gactctctcc tgggcttacc atgcgcagct gtgtccagcc actgttcccc
    19681 gccggcagaa taacggcgta agcctgccct cccctgcgtt caatactcac caatgtgaaa
    19741 ggcggcttaa tgacccgtgg ttttgacgac ttttttgcgg cagactgtcc acctccggga
    19801 gacggggtcg ccttcgtggc agtcgccaca gtgcgtttgc tccacgtgtc tttccaagac
    19861 gcgagggtat ctatacgcga agtctgctca gtcagcgctt tatgaacagc gtcgagcttc
    19921 atgcccgttt catcctctcg ggcaacagcc ctggcagtcg ccgcctgagt ctctttaacc
    19981 tctgtaacca gcgaagaaag ttgctgctca aacgcggtga gccgcagctc ctgctcactc
    20041 agcctgagct gccatttttc tccctgcagt ttcggaacga attgttgctg cctgtcttct
    20101 atggcctgca tacgatcggg aagtgtctgc agctgtccgc tgcggaacgc cgcatcaagg
    20161 gtggtaagct gtatctgctg ctgacgtact gtcagccaga ggaataagac agcacccagt
    20221 aataagcagt acaccagaac ggatgacact ttaaatatga gggaacggcg gtctgaagaa
    20281 ggatgccaca gacgactcct ctttcccccc agtcggtatg cagctgactg tgctgaagta
    20341 tctggtgtaa cagtgatatc agacgtatca atagccggtt cggcaggttc agtgaggtga
    20401 gcggataaag gtaaatcatt atctgacgga atatcgacag aagatgccgt cgttgtcgtc
    20461 atggtataag tcctccggaa aacggttttc gccatgacta tgcaaaaaca gttcagcgga
    20521 tacgacagac aaatcaaaac tcaaaagtga aaataaggga tccagattag cgtcaggaac
    20581 acaaactggc agcctcttga agatatgtgc gatatggaga taaagcgttg acggggctct
    20641 ttgccgcccc acaccccgca gactgcgtcg ccaccattcc ccgtcagcgg gcaatgccgg
    20701 caacgcagtg atgatctccc tgtaagtcat cacttcaacc ctgcgatagg cgcctgccag
    20761 ttcattaagc catgcctgca agcgaccagt tcctgtgaag gcgaagtttt aagcctaacc
    20821 ccctgtcatg gttagttcac ccagtacgtc agttcttcag caacatgcca gttgacgcca
    20881 tccttataag ttgttgccgc attcgcagtt cctgataaag cgataagaac agagaaatac
    20941 acccgttttt atttcataaa ttgattaatc aggaaatgct tggaaattca cccttaggtt
    21001 tatcgaatat catagcagga ataaccgccc cattatccaa tgcctgcatt tgtcgcgctg
    21061 agaaagtgaa ataacgtaat cggataggag gatatttttc tactttatct tttgtatacc
    21121 cgccaagagt gatactggtt atacgccgca attgattata tgcctgctga acctgctcat
    21181 cctgccagtc tagtgcctga tataccctga ggagcccgat cggctcaccc gaaataaggg
    21241 ggcgatagcg cagacacaac cccacacttt gaggtttacg cccctgctgc cagaagaaaa
    21301 ttaactcaac cggatccact gactgaattg actgcagacg gcataacaga gagggggtct
    21361 gcacagccca gtcgcgctgg ccgtcagcca tatctaccgg ataggaagag tttcccagca
    21421 gccagttaac atccacatca aaccatgtcg acaattgctg cagcaaaggt ttgttcagga
    21481 gatcaagcgt cctatcctga ctcgctaata cactggccct tattccccag gaagccagta
    21541 gctgtgcctg ttcgataaca ttcaatccat gagcatccaa cagcagacag aatcgctcat
    21601 aaagcgtgga cgttctgtcc gctatactct ctctcgcctc tgctacaatg ccatcaatac
    21661 acataccaaa catagcggcc cgggatatac ccagatgctc tgcgcacctg tccagaaata
    21721 cccgagtttc cggccgtatt cttactgaaa actgtgcact gggtgcagat actgatgccc
    21781 ccgtttcaag tggtatttca ccagatcgca ttaatgcaat tagcgcgtta taagttgcat
    21841 tcatactgac aaccttaaat attttcctgg atacaaaaga gtgaaattca actcatttca
    21901 ttttttcagt tctgcgttcc aatgtaatag aaagattaat ctcatttatt catcaggtat
    21961 aatggaatat ttcggtcgat ttgttctaat gtatgaagaa gattaaaacc atgtcgacgt
    22021 gaaatcgact gaaaaatata attctaaaaa aatatttatt ccgccaaccg atgaatgact
    22081 accattatcc cctcctcaga aggcaattga ataagccgcc actcctgtag cagcatttgc
    22141 gcaaaaatag caacacgttc ccagcgcgga agcgtaatgg gagcgatccg acagcgatat
    22201 cccgtcctgt gtgaaagaac ctgacaggta agcgctacct gagctggccg cataagatgt
    22261 gaacggaaaa aaacgggacg caccggccgc gccacgaggg ctgtctccag tgcctgaaca
    22321 aatgcctggt gatagcgtcg ggcctggcgg cggttcatcg cccccacccg atcaagcaag
    22381 gcaagatgta cagcccagta ttgacggcga cgatacgtta cactgaatac agcaaaccct
    22441 ttccagggcg tgaacagcgc aattaacgta aaacacgggc aatacagcgc cagacagaac
    22501 atcacaaaca aagcgtactc cacccctctg tccttttttg cagaaaatga acggcagcag
    22561 cgtaccccct taacgacgag aataaatcac gtaaatgact atccgtaacg gcaaatttat
    22621 caggcagcac tcaaaagagg atggatcatt acccgctcat gcttgccttc cggcaaatcc
    22681 ccggggcgag gcacacgctc tccccgctga gccgctttag ccagcgttcg tagcaacaga
    22741 acacctgcag cctccagcgc actctccctc gatgccgctg acactgaaag attgtcaaaa
    22801 tcgggtaggt gaacacgaaa accacaacag ccatctgatc cttcattaac ggattcaata
    22861 caggcaggat aagggacaaa atagggagca atcttttgtg tttgtcttcg gcgagcgtca
    22921 agtttactga caagctggta tgctctgaga tgggtataac gtttgagcat attcagggaa
    22981 cggtggccgg aaatagccgc cacttccata acgttgagtg ttcccagttc aaacagtcgg
    23041 ctaattgctt catgacgcag atcgtgaaaa tggagatcga cgatattcag gcgctgcaga
    23101 gccaccctcc aggcgctttt aaaaccagat gatgaatagt gaaaaacatt accgctaagt
    23161 gcgaccgtca ttccctgtag caaatgacgc gctttgcggg ataagggaac atctcgcgaa
    23221 ctgccgtttt ttgtcattgg caaatgggca acgccatgct gcaggtcgat atgttcccat
    23281 cgaagtgaca agatctctcc ttgtctcatt gctgtttcaa tggcgaggtg aaatatggcg
    23341 tgaagcgctg gattctgttc ctggaagtag cgggataagc gccgttcctc ttgtgatgtt
    23401 aaacgtcgat ctcgtcctcc tgatattttt ggcttacgaa ccatttcaac ggggttagtt
    23461 ctgcatgttc cccactctac gctggccaga ttatacagtg atgacagtaa agcgagttcg
    23521 agccggactg tgtttcctga aatacaccgg ccggtacgcg tattcacctg agacaaccga
    23581 tcatcgcggt aagacgcaat atccactgtc gtgatttcat ccatcatctt ctctgccaaa
    23641 ggatgtcgct gaatgaccct aacacgatag aattcctgct gatgcccccg tttatgcaca
    23701 gacacagtgg cgtagtattt atcaagggct ttcgacagag acattttttt tatgcgttgt
    23761 gggcgagaca ttgcagatac ctttgcgaga agaattgagg tttttctcca ccgtaacgaa
    23821 aaactctaat accctcaatc ctcgtaagga catacgtgcc aatccggtat ctgggtgtcg
    23881 ggtcaaaaca gattcactac acagctctac gacatagggc agaatgtgaa tgcgcagtac
    23941 ataggcattc atgcttattg cagttggaca catctatttt ctgctcctct aggggggcgc
    24001 cagagggtct acaatgtagg gaacgcttgg tatgtcacga atacccctta cggaggtttt
    24061 caaacaggat cgactgtttc cgtaacatgc ctgaatctgc cgggtgcagg gctttaattc
    24121 ataatccggc gccaggtaag ttcaaacagg ttaccgaaat agtacctccg gattcgtagt
    24181 tcccccatct gtagttagag atataccagc cgttggaacc gttcgagtgt atctcctgaa
    24241 acccgcccag aggtgaacca ttgagatatg tccatgcgca gtaggcatgc actccaatat
    24301 actgatttct tacattttta ccgacgttaa atgtctgaat attaaagttc agccgataag
    24361 aactccaaat accggattgg cacgaaagtg tggcacctgc tgtatcacga cttattgcac
    24421 catttacagg acaagcagtg ctggcaacat taatcttatc cagcgttaaa ataccgcctg
    24481 ccgatacgtc cccatccgag cgaatcttcc caccgcgaat ttcaccaccg gtataaaacc
    24541 ccttgttatt caggatccgt aaccagtcgt tatctgacat atacaaacca ccaccatggg
    24601 tctcatccat ccaaccttta ccactgcggg ttacaatcca tccccctgtg cttcgaatat
    24661 ctccccccgc agtgatcgga ccattactga ccagacttac gccaaaattc ccattctggc
    24721 cagccacatt actggccgta acagtgccga cgctattcag gttatttcct cccatatcaa
    24781 tagctgtgtg catcttgttc aaatccggac gaccattgac ctgaaaacga tacagcctgt
    24841 ccccgtcttc acgcgcccct gacaggtcat ccgtgctcaa catgacggcc agatgacctc
    24901 ttccggtgct ggtcccgtag gaggacagcg gaattcgcca gctgcgcatc gctcccaccg
    24961 ccgtttgccc gtcttcaacg tatcctccga agccggcggt aatgtctttc gagatctggc
    25021 ttagcgctgt aaaaggcata gcatgaccac cgcggctgac caccatgccc tgaagcaact
    25081 cctgattttg ctgattccgg actatcatcg cctgatactg ctggccataa ctgttggtct
    25141 cactaaagct cgccggcagc aaacctgtat tcttcagcat ttgagttgtt accactgcag
    25201 gtgtagttgt ggtcgctgat gccagcaccg tcggataaaa ctttccaaca taggatgaga
    25261 ctgcctgagt gaaacgattg gtttgcatgg ccacaacctg ccactcacgg gatttcagat
    25321 aatctcccat atatctggca gccaacgagg ccatcaccag aacaatgagt aacccggctc
    25381 ccacgctcat cgccacaaag ccgccatcat gtttttgttt tttcatctca gtatccactc
    25441 aggctggtac aacctatcca caatgactgg tatgcaccct gcacacagcc aggggcccag
    25501 aaccccacaa cgcagaaagt cccgatggac tatccactgc cacaacataa aaccactcag
    25561 cccaaaaaac gccgcctgca gtgcatccgt tacccccatc cagcctacca gggcacaaac
    25621 cagccagaca tctcccacgc caagctgagg tcgccgtcgg ttaacaccgt gacaaataga
    25681 ccccatcacc accgccatcg ccgcagtttc cataaagcga agttccggct cccgatgaaa
    25741 agcgagacag aacaataatc cgctacataa acaggctgcg gtaaacggtc ggggcaacca
    25801 accgctggtc gcatccatca ctcccagttg cagcaaaaaa ctgcacataa acagcattcc
    25861 gatacgtgtc atccagacct gaggtgccat aagtatcagc aaacccgtta ccgcaaacag
    25921 ccagataccc accacgacgg cacaatggcg tgagatatcc acctccgctg cggccagata
    25981 aagacgtacc ggccttaaaa gtaccgcccc gaaaatggcg cacccgataa aagcaggtat
    26041 ggcatacaca ggaggaaaaa tggtaccgat aagagagact gtcattgagc ccccgtttgc
    26101 cgctgataaa ttttccagat ccggtttgca taacgctccc gtgtttcatg ccggtcaggc
    26161 cggaaacctg cgttataaga gcccaggcag ttccagctca ccccacagac ctgaaaatgt
    26221 ttcgcaagga tccacgttcc aatctgcaca ttcaggcagg gtttgttcag caaatcattt
    26281 ttgtccctga tgacccccat cgagacaaga cggggaatat gcgtagaatt caccatcatc
    26341 agtccataat ccgtgctttt gattttcccc gtttttttgt cccggttatc atttgttgca
    26401 tgcggatcaa gattactttc accaatggcc atggacttaa tcagcagcgg ggagacatgg
    26461 tatttcgccg cagcggcatc aaagcagaat gcctgtaccc acagcggcac actgcacagc
    26521 gtcatgaata aagccagtcg ggaaaaatat ccacacatcc cgcctcctca gccgttgtag
    26581 ttaaaaacca gcgtattggt accggtccgg ccattatctg cagtgcattc actgctcgcg
    26641 atttctgccg ttactttcgc atcggtgtgg ttattgccgt ttattttaat accggacgtg
    26701 ccgcctgaac ggctcatacc tgttgaaatg gatacgcagg cagattgcgg aactttgttt
    26761 gtggtaatgg tgaacccatt attaaatccg gttccccccg ctgtatccgg cgccaccaca
    26821 atctggccac cccatgagtt ccacagtgtc gcggaaccgg aagcagggtc tccactgacc
    26881 gtcatccctt ttgccgcccc ggcctgaatt aacgtgtcgg tcattttagc gccactggta
    26941 aaagcataac cgtcaacgcc tttcatcatg ccaatggtgt tcgtggccag ggtctgatag
    27001 tttgtcagct ccgtacccgc atccttttta ccccacatcg accagaccgc cgcggctatc
    27061 accccaatga tcaccagaat aaacagtgca gtggcaccgg catctgccga cattccccgg
    27121 tcaggcctgt tgcatggatt taatgttgat acctcattca tcatctttcc ctctgtttca
    27181 tttttcattg aattgcttaa catcagtact gccccatact ctcggtcatc gaagtcgcct
    27241 caatcaccgc cacgaccaca acgccaataa gcgcaaataa catcaccatt gagaacagca
    27301 tcacggctat tccccgtcgg ttaactcgct tcacagtttc ctcgagccat tcctgcccaa
    27361 agcgcgcaat catctgagcg gccccgtccc cactgaccat agagagatag ttcacggctt
    27421 cttttgaggg gaaggcataa ccacattcac gcagcgccat accaaaagag gccccctcct
    27481 ccacttcctc catcactgcg ttcagacgta caacgagcca gggagaagca aagcggtgga
    27541 taacctgcag cgcagtcagg gttctgaccc cagcgcacag cagagccccc atattgatga
    27601 gaaaaatcgc gccctgaata tcactgtaaa ccgcccaggg tacatgtctg tccgcaagac
    27661 gacgcagacg gtccggacgt atccagttcg acagggacca cctggtccat gcgaccaaca
    27721 gtgccagccc ggcccccatc accacgccat gctcagtaaa aaaaatcagc aggccgttaa
    27781 ggcttcccag cactccggtc catgtctgcg gatctgacat cccggccagc gttggaataa
    27841 gctgcgtctg aataacaccc agcgtgccac cgagcatcgc aatgcaacct aggggataaa
    27901 cggccatcct catgatcgcc tgtcggatac gccgccggca gtcaatcagg atttccgcct
    27961 ctgcgagcgc ctcaggtaac cgaccactga acatacccgc gctgatgagc gccgcctcct
    28021 ccgccggaac ccagtttgca agagcatgct caagggagtt atccccgctg ttgtcagtga
    28081 gtgccgcccg gcagtcgtcc accagaaaac cgaaaccatg agtccgctgc ccaaaatcgg
    28141 tatacatatt gctgatttgc tccagcgcct ctaacaactt cacgccattt ctcatctgca
    28201 acgacagcat gcggtaaaaa cgcagacggt atccggacgt aaaaaaacgt cgcgccagcg
    28261 cccggcgaag acggtataaa ggactcatgc aacctccttc agcgcagcca tcccggcagc
    28321 aacgccttct ttaatggctt cctcaacacc ctgcttcatc ccctctctga cgctggctgc
    28381 aattaccatg gcaaggcgtt caatcagcga cgtatcaatg tcactcgacg atgcaacctg
    28441 atcacttacc acctgcatca cctcatcctc atcaagagga ataatcaaat cggcatccag
    28501 tgggtcaacc agcccgtcat tcagtttgtg aagcagatga atgcgacggg taatcccccc
    28561 catttcacgg atccagtaag cttttgcagc ttccttaccc tgctgtaata acagcctgaa
    28621 aagcgtagaa tccgtgcgaa ccacctccgc caccacactg cgtccggcca cccccttacc
    28681 gactgttgcc acctgtttgc caccgataat gaccgccttc cggcaggtcg ggcacccctc
    28741 ctcatttctg aaatgaagat tttcgggctg acaaaccccc tccactgaac agtacttttc
    28801 cagatattca cgttcttcgg tggtgagatg ttctttttta accgaccagg gaatacggca
    28861 ctcgggacac agcacctgaa ccagacgctg gctgataagc ccgaccaaca actgggcatc
    28921 tgccaccagt ccggcatttg cacccatcgt tatcattcgc tcagggatgg aaaaggccga
    28981 gtttgaatgc agggtactca gcaccagatg gccggtctgg gcggcaaaaa tcccggccag
    29041 aatggagata aggtcacgaa gttcaccagg taaaatggca tccggatcga gacgtaacgc
    29101 tgaggtcagc acccgctgcc aggccagcct gacttccgcc tcatcggctt tgtcacagat
    29161 aataggagtc tgtattgccc caacgatgcg tccctccggc ggatcttcaa ccgtcagtag
    29221 gcgcttttta taccgggtac gcttcagata gaggtcgctg caggcacgca gggtggtgga
    29281 tttcccggct ccggtcgggc cggacaaaat aatcatccct tctggcaggc gcaaagtgcg
    29341 ctttatcagg cggatttgtt tcggcagaaa accgagtttt tcgagcgtgg gaaccacatc
    29401 accatcatcc gggatcacgc gcatcacaaa gtgaaggcca tctgctgtcg gggtgtggct
    29461 gtaacgggcg ccaaataacc ccacctttcg cagaaacttt gcagccacac gaccatcctg
    29521 ttttcggccg gcgtagaact ggggttcggt cacatcacac atggaaagga tgatagtggc
    29581 cgcctgtgct tttccgtctt cttcagccag ttccgaaacg gtctccagtt caccgtgcac
    29641 acgcatctcg atgcgcgtca gtcctggccg ggtggtaccg tgaatatcag acgcgccgat
    29701 atctttcgcg accataaaat agttgagaac atcgccctga cggctgctga cctctttttt
    29761 gatgtcctca aggcgaagtc ctttttctcc cttctctgac tgctggcgag ccatttcact
    29821 gtacctgagc aactctgaac gggttaccag cctcattgtg acaccggggt tttcctccat
    29881 cagagacatt accttctgct gcaccgccac gtcggtacgc cgctggctgt caaccagcag
    29941 ctcgaggatc gtggtgtccg ggttgtggta aagcagaacc gcatcgttgt gttcagacat
    30001 aattcgtccc taaaacgtca gttgctgacc gtcactgagc gtgacggatg agagcgttat
    30061 tgccttcacc ttcagtgatg tccccggaat cacacttccc gtctgtacca ggctttgtcg
    30121 gccatccgga aatgacagcg tggcctgcag ggcgttacca cggccactca cttccagaac
    30181 cgtaattcgt ccagttgcag ggggggtgtg aacaggagtc gcattcatct ctgccggcat
    30241 tcccataacg aacggactgg tcgtgggcac attgccaaca tcccccggag tttgtgcaga
    30301 agtcagctct tttagcagtc gggctgcctg aacctttgcc tccaggagca ggtttttccc
    30361 ctgcagcgcc tccagctgtc cggccgtcac gctgttaccg gggaaaatgg ggactgtatc
    30421 tgataagtct gcagaggata tcgatgccgc tgcttccgta gcgggttcac tggcaggcat
    30481 tgcagaaatc acctctgcgg aaggaggaac tgcgagtgtg ggctgcgaaa atgcccctgc
    30541 gctgaacgcc atcaggagaa caccactgat gaaaacacta ttttttggca taagcataaa
    30601 gatgcccctc aatctgataa gtaaactgtc cctgaggact cagggtgtaa cccacagaac
    30661 tcagccgtac cccctgcata tcgagtccct gtaaaatcca ctcaggcatg tgtttatcag
    30721 tgatactgaa cgtgtattca tgccagtcct gtatcggctg gggcgcatcg ttgccggcac
    30781 catcaccggg catcgcggga ggagttttca cttcggacag agaaaaactg acctggcgtg
    30841 actgaaacca cgacaccgcc tgcatcaact gggtccccgc atccggcgca gtctcatcct
    30901 gtaatgtgaa tttcgcccat ggaataaaca ccacaccttc gttgccacct gaaacaaggt
    30961 tgaatactgg tgtacgctta aaaacctgct tcacccgctc cgcaaagcct gccgccgtcc
    31021 caccgggctg ccgctggtac accgtctcca gcccctcagc actgcaacga atccgttcga
    31081 gacgccaacg gtcaagactt acaggaactg cggcgcgcca gcgctgacag cggttcagaa
    31141 agtgtctggc cacaggcata tctgcccagg gatgtggaag gtaaacaggt tcaggtgttt
    31201 ttttaaacac gtcctgcacc ggtgccggta actcctgcac gacaggcgcg accggaggtt
    31261 cgggtaacct gctccaccag actgcaccac caagcagggc agccactgac agcactcccg
    31321 ccccgtatgg ccgcaaagga ttagacacgc ccgccactct ggcaaaccgg agctgtgccg
    31381 aagatacctg accgaccaaa gtgttccagg acaaggggaa ttccggtgat gaaggtatcg
    31441 tccatccgtc ctcaggagca gggttgaagg acagaaagag ctctctcgcc cggatgattt
    31501 gatctggagt tccgatcaca tctgccatcg gagatggcat ccccttcacc gtggccagaa
    31561 agacctgtct gccatcatca agctggtata ccccatagcc attgggtgta cactgctggc
    31621 tgaacagcgc cgccagggaa tacagcttct ggtgacgcca gccggcctca atttgcccca
    31681 acgcggtcaa ccggctcttg ccctgcttca ccgtcaacac aacgttcaga acaccccgac
    31741 gttgtacagg ggctcgacgt accgactttt gcttttcttc ccagcgaagc cccgctaccc
    31801 agttctggcg ctgccagcgc agaacctgcg tacggggctt gccggataac ggaatatctg
    31861 ccatatcagc caccgttccc catcagctcc ggggtgataa taatgaccag cgtactacga
    31921 gaatcatcgc cgtcccgacc gccacccagc aggaaattac ccggggtaaa ggtgccgttt
    31981 ttggtcatcc gggtattact ctgatcaaaa cctgtcagca ccagtgcctg ccctgcgcga
    32041 aggttagttt tctggctgag cgagcggagt ttggtgtacg gcatctcgat gtacgagttg
    32101 ccgtctttgg acgtgaagtt acgaatagtc ggtgggtcag acaggttgaa tgccacctgc
    32161 agttgcacgt caccaccatc ctgaatcagt ggcagtaacg tcatgttgaa gccggtagtc
    32221 atcatacccg gcgtcaggga tgtgggcacc cacatcggtt gtggtagtag ttgaactctg
    32281 tgccacgtag accgtctggt cggccatctg aataggtaca ggtgtaaggt tcgtggtcac
    32341 gctaccctgc gaggtgacca cactgacatc gccctgctct gacagagctt taatcagcag
    32401 actggagccg gcaaatttag ccgcacttcc ggttgctgaa tccagaatag ataccgacgc
    32461 cgacgttgcg ttggtgatat caccacttac attattgagt gaagcaccgg ctgagcgcag
    32521 ggacttgtaa acgatattcc agtccagtcc cagttgttcc ttacgtgaag tactgacact
    32581 cagtacctga acgttgagcc tgacctggcg gttcatctga cggttctgct gctcaacata
    32641 cgccgcgata ctgttgagta cagaaggggt atccgttacc gtcagagtgc cggtactggc
    32701 cgacagccag aaacgtccct tttgcggagt caccatggtt tccagcgtct ttttcatatc
    32761 gtcatagaca ttacggctct ggtcgaccgt cgtctgctgc gaagagcttg aatcccctga
    32821 caccgaactg tttgtactgc caccactggt tcccatactg cttgttgaac ccgaggtaac
    32881 actggcatta ctggtaatat tggtattcag aaatgtgaac tggaaagtac gcgtctccag
    32941 gagtgaaaac agaattgccc cgttatccat acgcggggtg aggcctgtcc tggccgaaat
    33001 catgtccagc agaccggaca gtttgccctg ccagcgcagg ccactcagta ccactggtgt
    33061 ggcggtcgcg cgtgccgaat caacagcgcc gcccagttga tccaacggaa ttcttccatt
    33121 gttatccggt gtggcttcgg ggttgccttt accggcaggt attcagaacg gggatgtggt
    33181 ctacctcaat taggaaaatc tttaatgata agaaaatatt acaaagtcag gctccgtatt
    33241 gcagctacag ccatcgtcgc cgcactttcg ctgccggcct gtacttttca ggaaatggac
    33301 aggatgtcgc gcagtgcgca agccagcggt gatattgccc gcggtcatgt cagtgagcag
    33361 atgcgatcct cacagggagc gctggtctgg acggataaac cctgggtcaa tctcaaaccc
    33421 gtcccgacag tgtcacgggg tatccctcag gaaaacttcc ctgactgtca gataacgctg
    33481 gcacgggacg gactgactct gccggaagtt ggagagcgaa tcactgcgct ttgcggcgtc
    33541 agggtaattt tttcacccga tgcgctggca gcaggtcagt cgtccggtac cacgcgggca
    33601 ctgaatggtc cattaccgat accggataac cagaccagtt gcccctgcgt caccgtgcca
    33661 gttaatgccg acccacctga ctgttcacgc agcgcatcca ccagacccgg gacttcaggc
    33721 atccagaccc acagccggtt agccacaatg acatgtcgga tacggctgtc aggagccacc
    33781 ggcagggcca gttctgacaa ggcgaccgtt ccgtccgtca gggtatgtcg gtagcgccag
    33841 tcattaattc ccgcagccag caataacatt tgccgggcca acagatacga actccccgac
    33901 tgctgcgctt tgacaacctc gcttcgctga gtggtctgga catgtccgac gacaagcaga
    33961 aatactgtgc ccagagcgac aatgaaccag cccatagcta cgaccggtca gccggtttat
    34021 ccgcaactga aaccaggcac tgcaggcggg aagcttcagc aaataagggc ttgtcagctt
    34081 tcttataaag gtcaaacacc tgaaccagcg ccgtctcaaa gttgccttta aataccaacg
    34141 gtgcgtcaat gcggtaatcc gtaggggtct gccagataac cacccagtgt cctccccccg
    34201 gacagtcagc tcttccggcc cagtcagtca gggactcttt gagcgtgctg ccgacaaccg
    34261 ccttccactc agggccactg gccactgcag ctacaggcgt accggttaac ggttttgttg
    34321 tcgtggccag taccgtagcc gtcgccggat ttacagcctt aacggttgag ggagacggtg
    34381 ttttagcctg agccttctct cccacaggcg ccggtgaatg agacgccgac agggtggtcc
    34441 cggtcaggtt ttttcctgtg aacggattgc gcggagccgg agaagagact tgtttcacgg
    34501 ggggggcaga ggacactcct gacgttaccg gtgtcccacc aggtctcagg gcagggacag
    34561 gaagtgactg actgaccggt ttcagttcag tacctttctt cgccgccagg tgctggccgg
    34621 cgatcacggg ttcagcttta ttccccggca gaacgccggt ataaggattg cgggtggttt
    34681 ccggggagga ggttcttgcg gcgccggtca cggcgggtgt gacagatgtc agtgctttag
    34741 ttttagcctg tacccgatat gcatcacgca atacgaaaca gacctcccgg ttgacttcat
    34801 ccacggacat tcgccaggca ggaccggcga ccacctgcag tgcctcactg agtcgcatcg
    34861 gcccaatttt gcgctgaacg gccggtaacg gccggttcag cagctcagaa aagtcagcac
    34921 cataatgtcc gcacagggaa taaccagact gaaacagcag gtagcgaaat ccgtcaccga
    34981 ctgagttaac cagttgccct ggcatagtaa tatcgatgag ctggttgagc ggttcccgct
    35041 gcgcatccgc acttttaata ctgaccagcg tgtaacgccc gctgcgagtc acctccggtg
    35101 atcgctggta aatatcagag aagacggaag gctgctgact ctgtgcaaat gcgctgtcgc
    35161 gagcggtttg ggtggaggtc tgctgtgcac acccggcaat caccagcggc aggctcaggc
    35221 agaaaagcgc ttgtgtgttc atgaaaaatc ccgtggatga ccgtaattac ggcaatcgtg
    35281 cggagatttg gcttagcgct caataaacaa ctctttatgc aaaaatgaaa aaaaaagcca
    35341 gcatcattgc tggcattctg catacatgaa tttactcaat gtaaagaagg tcgataaccc
    35401 tcgatgttaa tgacgcggtt gttccagcgt ctcgcggttc agacctgtgg atttaatcac
    35461 cacttccagg ctgacaccat tgtcaagcaa ggcatacgca gtttccagta acgtcttctg
    35521 ctcacgctca aggctggcct gacgctcctg ctgaatactc tgctgaatac cctgctggat
    35581 accttcttct ttcagttgct gtgcaattgt gcccatgatc aactccttat actccgggat
    35641 ctcaccggcc agttcgtata aaaacggcgt gatactctcg cttgtcatgc cattgtagat
    35701 aatataacac aggacggctt ccacctgcgc ccgggtattt ccggctagtc aaatcagctg
    35761 tacaacatca cgcagcagcg atgcagcgtc gcgatgccgg atatcccgct gaaccagctc
    35821 cagtaatgcc atacgacggt gagactgcag gtcgcagtcc tccatgacgc tgacatccac
    35881 caggggccac ggtcgggagt aaacctcccg cgccagcgcc ggtacatcga aacagtccat
    35941 ccagtctgta ctgtatgggt aaggccgcac cattccctga taaaacagta acggcaccac
    36001 caccggcagt gtcccgttac cctttttcag gtgggcatcc atcactgcca tcgagtaacg
    36061 catcatccgc caggccatca tccggtctgc ggtcgactgg tgttccacaa gacagtatat
    36121 gtacccggcg tgaccttctg cggtttccac cgaatacagt acatccgagt gcagttcgcg
    36181 aagcttctga tccacaaaac tacccggttc aagcttcagc gtatcgagac gaacctgcgc
    36241 gcggatatct gcgggaagat gaactgccag gaaatccctc gcagtgtccg gctcacgcag
    36301 aaaaagctta aacaggccat cgtgcccggg ccggttatga cccttttcgt tatccattcc
    36361 gtatccttca tatgttcaaa acataatgcc ttccacagga aggcattatt cagcgacaat
    36421 tttcaggaca gcacataaag cgcatgtctg gccacactgt gcccgaacgg cgcgaacggg
    36481 atatcatcgt cgaagtccat tggcggctca tttgcaggat gctgttgagg tggcatcccg
    36541 ctgtgagaag gcgctgctgg ttgctgaggc tgaccccagc cgccctgttg ctgcccactt
    36601 cccgcactat ttcgtccgcc caacatctgc atcgtacctg actggctgac gaccacttct
    36661 gtagtgtact tttcaacgcc agactgatcc gtccatttgc gggtgcgtaa tgcaccttcg
    36721 atgtatacct gggagccctt acgcagatac tcactggcaa tttcggccag cttgccgtaa
    36781 agaaccaccc tgtgccattc agtgcgctct tttttgtcac cggtctgttt atctgtccag
    36841 gtatctgagg ttgccagact gaggtttacc acggcaccgc catttggcat ataacgcacc
    36901 tcaggatcct gtcccagatt tcccaccaga ataactttgt ttacaccttt agaagccatg
    36961 agtatctctc cttaagcctg ttcacgctgt gaccatgtgc cctgtttgag cgcatgttct
    37021 gcctgagact gagtggaaaa gtactcaaca gattcacggg ataccggccc ttcttcattt
    37081 tgcgtgccga tgtaatatcc ggcaccactg cgaaggacct gtaaaggtaa ggataacccg
    37141 gcaaattttg ctgccagtaa accagtagaa gatgatggtg aagttaacat tgattgttcc
    37201 ttttacatta agtcaggaac acaccttcct gacggaaagt gtgtttccat caggaagggt
    37261 taaggagaac tcagaacgaa tcttccgcgt actgcttctg cgcgggctgg ctctgggccg
    37321 gaggagtgga atccggtttt tctgccttat agacaattgc accgtcaatt tttatccagt
    37381 caacccggat gaggcgagtc ttcaggctga cacggttttc accggcatga tcaccttttg
    37441 caagggtaaa aatatcggat ttgatcccac tgagaacaaa accgatcatt acttttttgt
    37501 cctcatcaca ggacttctgg cagcggttaa ttaaactcgt tgcgtctttg cctgcgactg
    37561 tgacatcaaa gcgggtgtag tctgcattat ctgtcggacc actaagggca ttcagcgtac
    37621 aacaggtaaa cttactgtta ccgttgacaa cctgacgtac attcgtgata tagcccagac
    37681 cgttgatatt cagattaaag tagttagttt ctttagacat gatgtttctc catggaatga
    37741 aatcgttgcg gagaaaacat ctaccctggc gggatgatgg attcccgcag ggatatcaac
    37801 gctggcaaaa cgctgatgat caataagttt aaaatatctt catcgcaaaa tgctgcgaca
    37861 gccgtttcca aagattaaag ggctgtacca cccgaaggcg tcacctctca ggctacgatg
    37921 acattggtgt gcaatcaccc gaaggcgtcc ctctcagatt gccggaacat tggtgttgtg
    37981 atcacccgaa ggcgctcctc tcagatcact ggaacattgg tggtcgctaa gcgacataag
    38041 gttcgcgacc atttttagaa cattagttaa ccctgtcaac ccgttaaata ttttttgtct
    38101 cgccataaaa aaatggccct cgctaacgcg aaggccattt ctcaaccaaa ctgttgcacc
    38161 agaacatgag gtaaaatcaa atctccgaag ccggtcaatg gctcagcgcg gttttcacgg
    38221 agtgattgcg ctttgaggac ggatccttcg agtaaagatc gttctcctga ctggagttgc
    38281 gaaaggcatg caaagctttc gaaccgttcc acagccatgg gtgctgctct tatcaaagcg
    38341 atataaggct accagaattc agcgaaagaa aacaacccgt tagtattcta ggctggcgaa
    38401 ggttttcgtc tgcgtcctct ggggcccttg ttaccattgt tcacgatacc tttgcactcc
    38461 ggatatttca ggcagcccca gaacaagcca ctctttccat tgcgctgcaa cgtcttgccg
    38521 ccacatacag gacagggtgg tgaaggtggc gcctgcatag tcagtggctg tgatctcccc
    38581 tgagcgacca gctgactgac ccactgactt tgctttgcca taaagtcatc caggctcacc
    38641 ctgcctgcag ctacctcatc cagcatctgt tcccacagtg ccgtaagtcc gggattcgtt
    38701 aacgttcctg gcaacacatc caccaggtta cgtccaagag gtgttgactt aagcgtcttt
    38761 ttctcacgca ccagaaaccc acgcttcaac agcgtgtcga ttatcccggc ccgtgttgct
    38821 tcagttccta tccccgcatt ctctttgagc acctttttca gcgcggcgtc agtaacgaac
    38881 gccgccgcat tggtcatcgc ggcaataaga gttccatcgt tgtacggagc aggcggtttt
    38941 gtctgcagta ccttctgctc agcgccctgc acctggcaga cctggcccgc ctgcatggcg
    39001 ggcagtgtgg tttcaccagt attatcctca tcatcttcgg acattttgcc aaacagagat
    39061 ttccagccgg gtttcaccaa aacgttacca cgggtacgga aaagctgacc gccaatatta
    39121 aatgtggcct cagtcacgtc aatttccatc tggggcagga actgggccag gtagtgcaac
    39181 ctgaccagct gatagacatt gcgctcagca tcactgagtt tgctcagatc accagtatgt
    39241 tttgtcggaa tgataccgtg atgagcggta atttttttat cattccagat acgtgacaca
    39301 aactgagtgt ccagactcgc gaccaccggc tgtagcgccg gatcagttcc gaccacagca
    39361 gacagtacct gtgggatttc ttctcgcatc gataacggca gataaccaca gtcagttctg
    39421 ggataggtcg tcagtttgtg ggtttcatat aacttctggg cgatatcaag taccgtctgg
    39481 gctggcatcc cccagtgtcg ggagcaggcc tgttgtagtg tgctcaggct gaaagccagc
    39541 ggcgctgatt gttttttcct ctcgatctgg caattgatta tcgcagccgt tggcgtttgc
    39601 cgacacaact gaaccacctg tgccgctacc cccgactgga tacaacgctt ctcttcatcg
    39661 caatactgtg cagccggtac ccatttggat ggaaacaaca cgccattcac ggccatcgtg
    39721 gcaataactt cgaagtacgg tttcgacacg aagttatcaa tttcacgatc acgctttacc
    39781 actatcgcca gcgttggcgt ttgtacccgg ccaactgaaa gtacgttacc gatacccgct
    39841 tcacgcccca ggagtgtaaa caggcgagtc agattcatac cgatcagcca gtcagccctg
    39901 ctcctgccca cgccagcata ataaagcgat tcagttcggg aagacggcca caaatcagct
    39961 aacgctgacc ggatactggc atcatccaga gctgacatcc acaaccggaa tacacgcccc
    40021 tgaaacttgc agtaatccag caactcacgg gcgattactt caccttcccg gtcagcatcc
    40081 gtggcaatta ccacctcatc tacctgttta agcagacggt taattaccgc gaattgggct
    40141 tttgcatccg ctttgactac cagtttccac tgctgtggta ataaaggaag cacatcggtg
    40201 cgccatggct taccatactg ttcgccatat acttccggtt cagctgtctc cagcagatgg
    40261 ccgcgagccc aggtgactgt aactcccgga ccattcagga atccttcgcc tctttgagtg
    40321 gcgccaagaa acttcgcaat atctctgccc tgagaaggtt tttcacacaa caccagacgc
    40381 atgataacac tcctttcaga aaaccagcct ttctgcgggc ttaaccatcg atgcgtttcg
    40441 aatcagcgac aaataaagaa gggtcagcca caatctgttc ttctaacggt tcttacagta
    40501 attgcacaat atctgctttg tctgcttttg catttgccgc cagtagaagt tcaatactct
    40561 ccttactgac tgggggtgaa aaagaggaac gtttttgccc caacaaaaca gcttcgtcaa
    40621 tttcacctgc gttcctgatt gcctcatggt actgagcatt ctgtaatgca aaatcgcggc
    40681 ggttcacctg aaaaaaacga tatttctgag cggcaccata gatctgacgg attagatggc
    40741 ctccccgtcg aaggctacgg tgaagctctt gccgggagat aaaaccataa tgcgcggcct
    40801 gaaaagcctg cattgccagt tggtcaaagc caaccagaag ccatacacat cgataaccca
    40861 gaggtgtacg actgaaaact ccaatattta aaggagaagc acagttgacc tcagaaatag
    40921 tcgcctgagg gggtagcatt gacattgact tcttgagtgc aacaagctct tcattcatct
    40981 tgaccgaagc ggactgcaaa agtgtctcaa gctcaagcat cttctgatca gcatacggat
    41041 tgtcattaaa tgaatcggca ttaatacgac ctgctttttg aatgaaggct ggcatactga
    41101 aaataagact ctgacgacgc tcttttttct tcccctcctt ttccccctct tcttccggag
    41161 gacgcccctg ccacaaattt attgcataat cagtattcaa cgctatgttc agcgccgaac
    41221 gtaaagcacc cgcttttctg gacactgata cctgttcttt ctcactcatc accaacccct
    41281 caccatcgaa taaaacgtat ttagtgaggg cgataattag tcaggtaagc cagaagtcac
    41341 aatgcaaaat tcttaatcca aagattaggt tttcaataag tggtcgtttt gtactatgca
    41401 gtctcgggca gtaaagctca ttttttaacc aacaagcctt ctggcagacc caaatacact
    41461 cactggttat tttttatacc atgctgccac tggcagcaaa gctcattttt taaccaatac
    41521 attttctggc agacccaaat acagtctctg gtcatttttt ataccgtgtt gccactggca
    41581 acaaagctca ctttttaacc aatatacttt ctggcagacc taaatacagt ctctggtcat
    41641 tttttatacc atgctgccac tggcagcaaa gctcattttt taaccaatac actttctggc
    41701 agacctaaat acagtctctg gtcatttttt ataccgtgtt gccactggca gcaaagctca
    41761 ttttttaacc aacacacttt ctggcagacc caaatacagt ttctggtcat tttttgtacc
    41821 atgctgccac tggcagcaaa gtatattttt taaccagtca ttgagaggaa ttcattctct
    41881 gacgaatttg ctccaccatc gccttcacga cttcctgacc tgcagggaca tcagcttcag
    41941 ctgagcatgt cgggattttt ccggcagcgg atggctcagc tggcacgaca gatctgctct
    42001 taacaggctg agtgacagca ggttccagac gatacagtcc tgccctcgct tgcctgagtg
    42061 tagtcagcaa gtagcccacc ggattgctga tacgtttctg gtgccagcca ttcaccacgc
    42121 tgagggcgat ctgttcagcc tgaactggtg atttctgtgc aagctgattc aactgttgag
    42181 ccagcatggg ttgttcactt tccggcagga tggactgcag accatcaggc cacacgaacc
    42241 cctcgggtat tccggcaacc gcatttttgc cactctgggg agatacgtac gtttttttaa
    42301 tcacactttg tgtgaaagaa cgtacgttat tgcagtccgg ttgccggact ctgtcgtaac
    42361 tgtctgattt caggctgagt ctgctatccg gactcggtga tttctccccc ctctcactac
    42421 tgggtctgtt taccggacta agtgatttat gctcattttt tatgctattc agactgagtc
    42481 cggtacccgg attttgatga gtgcgggcaa catcacccac cttggacggg cgggtcagac
    42541 gttccgcaat ttccgtcatc cgcgaatgcc tgtgacgcat catcggatca tcaagtatcc
    42601 cgttcagtac atgaaaggcc gtgtcgctga cctctctgta tttgtgctgg caggctttac
    42661 ccaccatatc cagccatccc gggtcaaaca tctctgcatc cttcgcactg actggttcat
    42721 catgctgggc gtaaatattt ccccgtaccc ggcccccggt atcacgcacc cgcttgcaca
    42781 aactcaacca gcccgttagt cgaagcatgg tcagcgcacg gctcaccgta tcgcgtgacg
    42841 cctgtccgga accgggggaa gaaagcagtt tctgaagttc atcatatgag gggaagatgg
    42901 cgccgtcgtt ctgcagggca tactgccgta tcattatcca gcacatttta tccagaggag
    42961 aaaggcgcat atccaggatt agcgcccgcg ggtaggcgtc gtgaatatta cctgtaaaca
    43021 gcagcccgtt acgctcctgc cccgacgaac ccggcgtacc gtcaagccgt gcctgcatct
    43081 tcgacaaggt gtagtcaatg atatcatctg caggcaaacg gtgaacggat gaaccgggtt
    43141 cttccatcac ctgagccgga gtttgcatcg ttctttctgt tgttatcgat gcgtctctca
    43201 tcgtttcagt tcccggttat aggtctggtg agacataaat aaccagcttt tacctgcatc
    43261 cttactcagc agacgccagc gtaatcccag atcaatcttg agataacctg tctgtcctat
    43321 ctggctgtag actcgctttc cctgctggta cagggaaagc agtgtacgcg cctttgacgt
    43381 gacagcttta ctcacatttc tcgggtcagt acggtaaaac tgaaaggagg gtgccagtga
    43441 atccatcagg ctacctcccc ccgtacacca gtttttgatt aatccccaga tcaccgtgag
    43501 actgacatca gcctcttccg caataagcat catagtttca agagagttaa gactttctat
    43561 atcgctgata ttggcctcat gccagagacg ccatatcttc gcttcacact cctcatcagg
    43621 tgactggcaa cgtccctgac gtgtctggat cccctcgagc cgccgtttag aactgacatc
    43681 tgaagcattc agaccaaaga agatccccat catctctatt gatgcaccaa gagcaatagc
    43741 acgatcaatt cgttcgctac gcttttgctc acgattggcc tggtccagca ttcgttttag
    43801 attttcatga tgtattgcta catttaaaac agaaacaggg ctgcctgaca gataatgcag
    43861 ttcttccatc gtcagacttc tgaggagacg catttcttca ggtttcaacc ccagcgcctc
    43921 acatcgccga atatttccac ctctcagttc cataaccaga ttgaacaaaa gactgttggc
    43981 accctgtgca agtgaaaaag tcatatcgcc tcctgaacgt gaacactttc attatccaag
    44041 acaattaatt gattacaggc ccctggagcg agaataaacg ccagaacgtt aaccattgga
    44101 tacctcctga agcgaatgct cctcactgcg atagtccata gccggataaa tctcagcctg
    44161 cctaccagct gtccatgcag cctgcctcac ttttttggcg ttacgacacc cttccggctg
    44221 ccgtactttc gcaggggtca gattgcgctg ctgctgtgtt aaccagcggt cgagtagaac
    44281 tttttctgat gtttcaggtt caaatgactc cagaaccgtc catactccgg ccacccagta
    44341 caaacggtat tcatccatac ggcgacggat agtggaaagt ttcagtaacg gatgtgcgca
    44401 cgcggtatgg agataatgtt cggcatcacg cttcaactga cgggagacaa cgccaaacag
    44461 ataacccgcc accgccggac gttcaccaag cccgtaaaat gttacgctgc gacgcttctt
    44521 atgatcactg ttctgatacc agccgtaata gctgcgacag cccgcggtca tgcaaaccac
    44581 tgtaaccaga gcattcagcc aacccggaac cgaaagagca ttactgggga tattcctgca
    44641 ggtctcactt gttatttctc ccggtaccac gctcgccggg gttacatcgt atttcatcat
    44701 caatgcctgg gcctgccgta aagccactga tgcctcatag ggattacctg ttttttcggc
    44761 cagtaccatt agcttcttga tacgtgaaag aactttttca ttcgccgaca cgagtcacct
    44821 cctcaatttc cggatatgcc acaatatcaa gcatctcagg acgaatacgg gtcagcctta
    44881 gctgaacacc gcaacacggg caggcatcaa atattaccga cagcccgcgc tttgctgcat
    44941 tcactacgcc tcgacttccg acaggaataa ccgccagtcc actgctcagc tcctgtgtgg
    45001 tgacaaccgt ggcaccgacc cactggtaat gtgagcgggg ctttttcaga ctcttcattg
    45061 ttttttgtct cctgattctc gccattcctg acagtacatg cacaggctta ccccggggat
    45121 ggactcacgg cgcgagtcag ggatttcatc accacagtcc cgacaatgtc gtcgtgatac
    45181 atgtccctta atccgaagag cagcccggat ttcggcaaac ctgttgtcaa tgtttacctg
    45241 cgattcgttc tgagccatcg aatcatcaac atcaatgctc atgcctcctc ccgtcatttt
    45301 gttcagccgc catatttctc tgcagctcgc gcagacggcg aataacacga ataaggcgca
    45361 gactcttcac tacatgcaca tcgtcaaaaa caggcgtatc tcccgctgat tgggagccaa
    45421 agaagttgag acagaacata aacatgttga attgtttatt cggcacgtga ccggaaagcc
    45481 ctgccagaaa aagagcaaat tctccgccgt gttctgaaac agagaacccg gccgcactgg
    45541 catttttatc ttcactgaca tgaacctcac agcccatcgc ctctgcaagt tcataagcaa
    45601 gccggtaagc catgtcctgc agatgttcga tatcatcctg cagagccgga atgacccaga
    45661 tatcagtaac aggctcgagc cctacgttgg caaactcaac tgaggaaagt gctggttctg
    45721 tgggtaaaag tgagagaccc ggcatctcgc tggcaatact aacggcgtca gaaggagtat
    45781 ccgcagtcaa tcccacctga gcgccagcga aagctgatgc actgacagcg atatttccgg
    45841 cgtcgggaat aaagtggtac tcatcaggaa taacatcacc ggttaaaact gagggccccc
    45901 cgaggaaatc gttctggact tcagctttag gtaaacgagg tgatccacaa gaaccgaacc
    45961 attcgccggt cacatcatcg ttatccccat tgtcattatc tggatctggt tgtttaggta
    46021 agacaggggc gttattcagc ttcggtttta aagaggaacc gccttgttga ttctcatcgt
    46081 ttgcagtacc cggcaatgat gcagtgctct gccatgtctg gcgatctgca tccaccagat
    46141 gagatgccac aggttctggc tcaccaaata actttctctg gttacgtgcc ttaggatcca
    46201 gctcaagtag ccaccgatca tagttaagag aagggtgtgg taaaacattc accaacatac
    46261 cgataaactc atctctgaac atttcgaagg aatacacctc cggatcgtca aactgagtac
    46321 agacatgacc gaaaatctca ttaaaatcac tatcagtctc agtcatcacc gaatattgct
    46381 gccaaatttt taaagcatca gctcgcaaat ttaataaatt aactatctgg ggcttaccta
    46441 acccagaaac cagcaactcc ggcataaagg gataaagata ttccaccgta tgttccatac
    46501 ggctgatcat tgagttgtga atggggtatc cctgctgtcc gagcaggtcc gccagctctc
    46561 gcagggttac cgttcgtcca agagtttctt catgaatggc gcgggctttt tttattccca
    46621 gcgctttgtc gataaaggtt agatcccccc ttacatcatt ctcggccaga tgccctacca
    46681 gacattcaag cctgccaggc catggcttga acagagcatg gaagcggtaa aagcgttcat
    46741 cctgtgtttc agcaaacagc tctcgcagaa tggcgtagcg ggtgttacca ccatcgctga
    46801 aaatataagg agagccgggg atatccgggt ttttcgtcac tttcgggacc gtatccagac
    46861 cacgggctct gatggattcc ttgatttcat cgtacttagg attgcgtgtt gtgcgaggat
    46921 tgtccggatt aggagctacc tcatcgagcg tcagcaccat cggcatttca ctggtcggca
    46981 taatcgcaac agcagcggtt gtagctgcag atgattcctt cgccccctgt agcagcgcat
    47041 tattaagatt taacagtggt gctttagcca tagctcacct ccccataacc aaggtgatac
    47101 tccgagaagc gcatatactc cccctcaaag cgaactttga cagtgcccag cggcccctga
    47161 cgttgcttac ccagaatgat ttcagctatg cctctatccg gggagtgctc gttataaact
    47221 tcatcgcggt acaggaacat gatgacatcc gcatcctgct ccagtgagcc ggaatcccga
    47281 aggtcactga ccatcggacg tttatcctga cgctgttcaa cgctgcgatt gagctgggat
    47341 aaagctgcca cagggcacct tatctctttg gccagtgact tgagcgaacg ggaaatctcc
    47401 tgaatttcct gagtgcggtt ctcccggcca ggacaactca ttaactgaag ataatcaaca
    47461 agaataagtg agggctgacc gtatttacgc acattacgcc gcgcgctgat acgtaacgtg
    47521 gaaggcgtct gataactggt atcgtctatc agcaaacgtc cttcccagga ggtcagtttt
    47581 gctacggcat ccgcaagtaa actccactgc ccttcgctca gcagaccttt gcgcaggtta
    47641 tcgaagggca ctctggccag cattgaaagc agacgcatta tcagctgctg ggttggcatc
    47701 tctatgctgt agaactgaac ggtcttgccg ggactgcctt ccagcgcagc aacggcatgt
    47761 ttcagtgctt ctgccgtttt ccccattgat ggccgggcac ccagtaaaat caggtcaccg
    47821 tcctgccagc cacaggtttt ctcatccagt tcagcaaaac ctgtcgctgt accggtcaca
    47881 ccgcttcccc cactgaccga ttccagccag ctgaccgtgt cagcgacctg agtcgttacg
    47941 ctcagacaaa tgtcggggtc acaggcctgc tgagccagac taaataactg cttttcggcc
    48001 ttttcaatca gaccgggtat atccgcatcg ccgactgagg ccagttgatg tagctcatgc
    48061 cccagcttaa ccagccgtcg cttacgactg tactcgcgca caatttcggc ataagcaacg
    48121 atattggcgg cgctgggcgt gttttttgac agttcagcca gataagcgac ccccccgcac
    48181 cgctccagca gatcttttcg ctccatggat tcggacaggg ttatcaggtc aatgggcagg
    48241 ccagcactga ccaaccgttc tatctcccga aaaatgatct gatgctggcc ataataaaaa
    48301 tctccggaat tcagaagcgg cgcaatttca tcccagcggt cgttatcgag catcagtccg
    48361 cccagaacac cggtttcagc tccgacatta aacagcatgg atactgcaga aacagattta
    48421 tggctcatac ctcatccgcc ccctgaccaa atccgggctg aggccggtta accagaaccg
    48481 catcaaactt atctttccat tgaggaaata actcacagac caggtggtgc atggactccg
    48541 ctgccggcag gcttacccgg tcagttttat attcgagacg atgtactggc tgcccgcacg
    48601 catgcccacg tttgtagact tccagttgct ctatttcggt attcagcatt gatatggcaa
    48661 tacggtctga ctgggggtac tgacctttat ccacgattgc cttgagttcg ttgagggtgt
    48721 ttcgatccag tacagtgggt tcaacacagt tggcgagaat tcgaatatcg ggaatatgga
    48781 taccgtaggg ttccagaacc agaagtttgg ataaaagacg tacagtgccg cgtaggaact
    48841 cacgtacatc gggtaaaatc ggtttaataa cacccatgac gctttgagtc gcagcgagca
    48901 ccacgagctc caccatcacc ccgccagcgc ctttggaatc gacgattatg acgtcatatt
    48961 gtctgaaaag aggatgctgc aggacattac gcagacgcat tctgccatca gctgcatgca
    49021 gcatatcatt ggaaagacga tcgtcaggat cgttggaaat gatgacgtca agattgggaa
    49081 taaccgtgcg ggaaatgatg ctgtcaggtt tgttaaggtc agcagtctgc atgagtaatt
    49141 catacagtcc gcagggtgct tcatagtgaa gtttaaaaat actgctggct gttggctgat
    49201 tataatcacc atcgattagc agtgttttca gaccagcatc ggcggtgtaa cccgcaatat
    49261 tgcctgcctt ggttgacttc ccttctccgc ccttagtgga tactactggc aatactaccg
    49321 ggaattgttg ctcatcaggg agtaacaacg aatgcggtga aacctgctgt gccaaatgaa
    49381 tactggcgtc tggttttctt tctacagact ccccggttga aacctggggg gaacacttaa
    49441 cgcgagatac agtttgcatg caatacactc gaaatttatt cgaatgtgtt cgcctgcctg
    49501 ctaccaattc aaaaagtcaa agcggtgtct aactttttga caaggggatt gaaaatcccc
    49561 gtgtccgtgg ttcgattccg agtccgggca ccacttattc agaaaatcca gcctatggct
    49621 gggtttttgc ttttctggga atggaaatcc gtagccccca tctctggcct gattagctat
    49681 aacgggaagg ccagattttc tctggcgcaa cgcccagcgc ttcggcgatc agccgctcat
    49741 ctttgggcct gggtcaaaag cttacttagc tacagggaga ttattaccag taataacgcg
    49801 tatcactcca tctgacggtt cgctagcctc gacaagtgaa tccaatatct ccgccatgaa
    49861 ctttttcatc actgacaaca acaattcctt cgccaatttt agcatttttt ctttttcggt
    49921 ttctttattc ttaaatactg tttccgactc ttgttcataa tcataaatta atactcagta
    49981 catcatgact gatggtagtt atcggggtaa cagagcacat actttaaaat aattattcat
    50041 actgtgttat tacggaaaga ttttaaccta atgcgtgtca gtcaggcacg cagataaaaa
    50101 ataaccgggg acaaaagtta aacaaaatgc tgttagccgg aagtatcagt attgttctgt
    50161 tgtccgctac agtcagtccg gtatggacag acgataatgc cagtgcagcg tcctgctttt
    50221 ttacctgtat gttgaataac catttcaata aatcattata gaatcacatc tgtttattat
    50281 tgcctgatcc ggggtgagtc tttatgaaaa gtcgttattt actatttttt ctaccactga
    50341 tcgtagctaa atatacatca gcagcaacaa tgcaaccctt tcattctcct gaagaatcag
    50401 tgaacagtca gttctactta ccaccaccgc caggtaatga tgatccggct ttccgctatg
    50461 ataaggaggc ttattttaag ggctatgcga taaagggttc cccacgatgg aaacaagctg
    50521 ctgaggatgc agatataagc gtggaaaata tagccagaat attctcgcca gtagtgggtg
    50581 ctaaaattaa tcccaaagat acgccagaaa cctggaatat gttacagaat cttctgaaaa
    50641 tgggcggcta ctacgctact gcttcggcaa aaaaatatta tatgcgtact cgtccctttg
    50701 tcttatttaa tcattctacc tgccgtcctg aagatgagaa tactttgcga aaagatggct
    50761 cttacccttc cgggcatact gcttatagta cacttctggc attagtatta tcccaggcca
    50821 gaccggaacg cgcgcaggag ctcgccagac gaggatggga gttcgggcaa agcagagtga
    50881 tatgcggtgc tcactggcaa agcgatgttg atgctggccg ttatgtggga gcagtagagt
    50941 ttgcaaggct gcaaacaatc ccggcttttc agaagtcact ggcaaaagtc cgtgaggagc
    51001 tgaacgacaa aaataattta ttgagtaaag aagaacgccc cgaacttaat tactgaaggt
    51061 gaaagtcttc ccgcaaactg gccacagcaa atgaaaggaa gtgcaactgc gtaggggcga
    51121 ccgggcgtgg agaacgcctt tggtttcccc gattcgcatg aattcaacgt ccccgtttgc
    51181 agtccgtcca gaccgtcatg acgtcgttgt ccggctgaag cggtaaaacc ggtctggctc
    51241 actgactatc cacagcgaat tccggccatc agaagctaag ggatgcgttc tggagtttaa
    51301 acactctcca ccaaatcccc caacgtcacc atcaacatca tcggatccat cggcgacggt
    51361 acaaacccca cccactgata aaattcccgc gcttcatccg acagggcgtg aaccagcatc
    51421 ccacgaatgc cgatagtctc cgccacctga ataacccgca gccctgcgtc gcgtaccagc
    51481 gcccgagcga cgccctgccc atgaagcgat ttatccaccg ccagacgccc caataccaca
    51541 accggaatcg ggtcaggcat attgcgacga aagcgaccgg gggaggtatt cgtcgtgacc
    51601 gcgctggacg ccagcgagta ataggccagt acgttcgaat cgctgccaca acacacaaag
    51661 gtacgggacg cgccagtggt ctgatttttc atcgcccgct gtttcagcca gttatctata
    51721 gaatccacac cgcagcaaaa cggagtaaga atatgtccgg catgaagcgg ctcaggggtg
    51781 gagatcattt ttcctgctcc cacggcgcag gggtctgcat ggttttacgc agtgcggcat
    51841 taggtgaagg tgtttgatcc aaacgaacga gaaattcctg ataagcctct ggatcggcca
    51901 taatgatgcg ttgttcgata agcacttctt ctgcggcagc acgggcagct tccaacacaa
    51961 agtctgtgcg gtttttccct ctggctttcg ccgctcgatc aataagatcg cgctcggcgg
    52021 gtttgatacg caggttcaga gtttcacgtt tcatcgccat actgtttgcg gctggcatag
    52081 tgttgtcctc ttgtacttct gtggatatta agtatacaac acgcgtaacg cagatgtcat
    52141 tacgataaat ttagaaggaa tggaaccgga gtagcgaacc gaaaggtttt ctactcattt
    52201 atagattcag taccaggctg tgcgctggca ttcgctgtga gtgattcctc ctcggggccg
    52261 acgcagcaaa agattcaata ctgccgcgcc aaaacacgca acattatata atcagaaagc
    52321 ataaacctaa cggatacgca cagtaagaac ctcaataacg tgttacatcg tttttcataa
    52381 agccaaccat acgattgaat gtttcccctc cccctcaaac ttccgg
//
LOCUS       DAJVKX010000016        52293 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000016 DAJVKX010000000
VERSION     DAJVKX010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 52293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52293
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.016"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(223..738)
                     /gene="luxS"
                     /locus_tag="OPY25_000895"
     CDS             complement(223..738)
                     /gene="luxS"
                     /locus_tag="OPY25_000895"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCS0926569.1"
                     /translation="MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPN
                     KEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELA
                     LPKEKLQELHI"
     gene            complement(888..2444)
                     /gene="gshA"
                     /locus_tag="OPY25_000896"
     CDS             complement(888..2444)
                     /gene="gshA"
                     /locus_tag="OPY25_000896"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HCS0926570.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTVH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGVTEGEAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPF
                     EKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYAR
                     IGVEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLG
                     IGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEEYQKVCDELVACFDNPELTFSAR
                     ILRSMIDEGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTE
                     PFAAWLAKHA"
     gene            complement(2521..2946)
                     /locus_tag="OPY25_000897"
     CDS             complement(2521..2946)
                     /locus_tag="OPY25_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCS0926571.1"
                     /translation="MSDGLSLLSLFASSFLSATLLPGNSEVVLVAMLVSGVSHPWVLV
                     LTATMGNSLGGVTNVILGRFFPLRKTSRWQEKATGWLKRYGAATLLLSWMPVIGDLLC
                     LLAGWMRIPWGRTIFFLCLGKALRYVALAAATVQGMMWW"
     gene            complement(2943..3509)
                     /gene="yqaB"
                     /locus_tag="OPY25_000898"
     CDS             complement(2943..3509)
                     /gene="yqaB"
                     /locus_tag="OPY25_000898"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HCS0926572.1"
                     /translation="MYARYAGLIFDMDGTLLDTEPTHRKAWREVLGRYGLRFDEQAMV
                     ALNGSPTWLIAQSIIELNHADLDPLSLAREKTDAVKSILLDCVEPLPLVEVVKAWHGR
                     RPMSVGTGSESAIAEALLAHLGLRRYFDAVVAADHVQHHKPAPDTFLLCAQRMGVMPT
                     QCVVFEDADFGLQAARAAGMDAVDVRLL"
     gene            complement(3880..3956)
                     /locus_tag="OPY25_000899"
     tRNA            complement(3880..3956)
                     /locus_tag="OPY25_000899"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3920..3922),aa:Arg,seq:acg)
     gene            complement(4153..4229)
                     /locus_tag="OPY25_000900"
     tRNA            complement(4153..4229)
                     /locus_tag="OPY25_000900"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4193..4195),aa:Arg,seq:acg)
     gene            complement(4292..4368)
                     /locus_tag="OPY25_000901"
     tRNA            complement(4292..4368)
                     /locus_tag="OPY25_000901"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4332..4334),aa:Arg,seq:acg)
     gene            complement(4431..4508)
                     /locus_tag="OPY25_000902"
     tRNA            complement(4431..4508)
                     /locus_tag="OPY25_000902"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4471..4473),aa:Arg,seq:acg)
     gene            complement(4512..4604)
                     /locus_tag="OPY25_000903"
     tRNA            complement(4512..4604)
                     /locus_tag="OPY25_000903"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4568..4570),aa:Ser,seq:gct)
     gene            complement(4908..5093)
                     /gene="csrA"
                     /locus_tag="OPY25_000904"
     CDS             complement(4908..5093)
                     /gene="csrA"
                     /locus_tag="OPY25_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HCS0926573.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(5328..7958)
                     /gene="alaS"
                     /locus_tag="OPY25_000905"
     CDS             complement(5328..7958)
                     /gene="alaS"
                     /locus_tag="OPY25_000905"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCS0926574.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPNNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTGENWFALPKERLWVTVYETDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIEAVAKVTGSTDL
                     GNKSLRVIADHIRSCAFLVADGVLPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIEVMGSAGEELKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLQGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVEAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGAGFTFAVDDTQKYGQAIGHLGKLSAGALKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVAQKGSLVSDKVLRFDFSHNEAMKPSEIREVEDLVNAQIRRNL
                     PIETNIMDLDAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGIRRIEAVTGEGAMATVHAQSDRLNDIAHLLKGDSQNLGDKVRAVLERTR
                     QLEKELQQLKDQAAAQESANLSSKAVDLNGVKLLVSELAGIEPKMLRTMVDDLKNQLG
                     STVIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVQGWVSAKLQ"
     gene            complement(8194..8694)
                     /gene="recX"
                     /locus_tag="OPY25_000906"
     CDS             complement(8194..8694)
                     /gene="recX"
                     /locus_tag="OPY25_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCS0926575.1"
                     /translation="MSEPTSRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKN
                     GPEEIDATADDYERVIAWCHEHHYLDDERFVMRFIASRSRKGYGPARIRQELNQKGIS
                     RESTEKAMRECEIDWSEMAREQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQI
                     WRNFAD"
     gene            complement(8811..9872)
                     /gene="recA"
                     /locus_tag="OPY25_000907"
     CDS             complement(8811..9872)
                     /gene="recA"
                     /locus_tag="OPY25_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCS0926576.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     VYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYNGEKIGQGKANATTWLKENPATAKEIEKRVRELLLSNQNA
                     TPDFAVDDSEGVAETNEDF"
     gene            complement(9957..10454)
                     /gene="pncC"
                     /locus_tag="OPY25_000908"
     CDS             complement(9957..10454)
                     /gene="pncC"
                     /locus_tag="OPY25_000908"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HCS0926577.1"
                     /translation="MTDSELMRLSEQVGLALKARGATVTTAESCTGGWLAKAITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSESVVVEMAIGALKAARADFAVAI
                     SGIAGPDGGSEEKPVGTVWFAFASVSGEGITRRECFSGDRESVRRQATTYALQTLWQQ
                     FLQNT"
     gene            complement(10920..11999)
                     /gene="mltB"
                     /locus_tag="OPY25_000909"
     CDS             complement(10920..11999)
                     /gene="mltB"
                     /locus_tag="OPY25_000909"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HCS0926578.1"
                     /translation="MFKRRYVALLPLCVLLAACSSTPKSSETQATTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVSKHGFDRQQLQEILSQSKRLDYVLRLMDRQAPTT
                     QPPAGPNGAWLRYRKQFITPDNVQNGVAFWNQYEDALNRAWQVYGVPPEIIVGIIGVE
                     TRWGRIMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFAGA
                     MGYGQFMPSSYKEYAVDFNGDGHINLWDPVDAIGSVANYFKAHGWVKGDMVAVPASGQ
                     APGLANGFKTKYSISQLAAAGLTPQQSLGNHQEASLLRLDIGTGYQYWYGLPNFYTIT
                     RYNHSTHYAMAVWQLGQAVALARVR"
     gene            12254..12817
                     /gene="srlA"
                     /locus_tag="OPY25_000910"
                     /gene_synonym="gutA"
     CDS             12254..12817
                     /gene="srlA"
                     /locus_tag="OPY25_000910"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCS0926579.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQQRIERFAQRCAGNPLSRYLLLPFIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLGLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLTGAVS"
     gene            12814..13785
                     /locus_tag="OPY25_000911"
     CDS             12814..13785
                     /locus_tag="OPY25_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCS0926580.1"
                     /translation="MTRVRIEKGAGGWGGPLELDVTPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAVDGFKEGEPPEAEIGAAIIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITLVGETSARPQPAKTTLGRDYDTSKKITEQSDGLLAKVGMGMG
                     SAVAVLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGL
                     VTLALICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACD
                     FIPVGLSLAEAKQDTVRVGVPSVLVGRFLTGAPTVLIAWFVSGFIYQ"
     gene            13797..14159
                     /gene="srlB"
                     /locus_tag="OPY25_000912"
                     /gene_synonym="gutB"
     CDS             13797..14159
                     /gene="srlB"
                     /locus_tag="OPY25_000912"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCS0926581.1"
                     /translation="MSVIYQTTITRIGQSAMEALGEKMLITFREGAPADIEEFCFIHC
                     HGELTGALQPGARCELGQHCYPVTAVGSVAEQNLRELGHITLRFDGLREAEFPGTVHV
                     AGPVPDDIAPGCILTFVA"
     gene            14171..14950
                     /gene="srlD"
                     /locus_tag="OPY25_000913"
     CDS             14171..14950
                     /gene="srlD"
                     /locus_tag="OPY25_000913"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HCS0926582.1"
                     /translation="MNQVAVVIGGGQTLGAFLCRGLAEEGYRVAVVDIQSDKAANVAQ
                     EINADFGEGMAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLCIKPDEVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            15027..15386
                     /gene="gutM"
                     /locus_tag="OPY25_000914"
     CDS             15027..15386
                     /gene="gutM"
                     /locus_tag="OPY25_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HCS0926583.1"
                     /translation="MVSTLITVAVIAWCAQLALGGWQISRFNRAFDKLSQQGRVGVGR
                     SGGRFKPRVVVAVALDEQQRVTDTLLMKGLTVFARPVKIAAMQGKHLHELQPDVIFPH
                     DSLAQNALSLALKLKHG"
     gene            15585..16358
                     /gene="srlR"
                     /locus_tag="OPY25_000915"
                     /gene_synonym="gutR"
     CDS             15585..16358
                     /gene="srlR"
                     /locus_tag="OPY25_000915"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HCS0926584.1"
                     /translation="MKPRQRQAAILEHLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     NAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKALIAAAAVKYIHDGDSIILDAGST
                     VLQMVPLLSRFSNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEQFSFDKLFMGTDGIDLNVGVTTFNEVYTVSNAMCNAAREVILMADSSKFGRKSPNV
                     VCSLETVDKLITDAGIDPAFRQALEAKGIEVIITGESNE"
     gene            16351..17316
                     /gene="gutQ"
                     /locus_tag="OPY25_000916"
     CDS             16351..17316
                     /gene="gutQ"
                     /locus_tag="OPY25_000916"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HCS0926585.1"
                     /translation="MSDALLNAGRQTLMLELQEASRLPERLGDDFVRAANIIIHCEGK
                     VIVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSVALLAMTGKPHSPLGRAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNNVHHLMRQGDAIPQVMLATSV
                     MDAMLELSRTGLGLVAVCDEQHVVKGVFTDGDLRRWLVGGGALTTPVSEAMTPNGITL
                     QAQSRAIDAKELLMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(17313..18833)
                     /gene="norR"
                     /locus_tag="OPY25_000917"
     CDS             complement(17313..18833)
                     /gene="norR"
                     /locus_tag="OPY25_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HCS0926586.1"
                     /translation="MSFSVEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALL
                     RYESRQFIPLAIDGLAQDVLGRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNA
                     LLIEQLESQNMLPGSSGVFEPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETG
                     TGKELVAKAIHQGSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLFVPPLRERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGAR
                     RHLLNYGWPGNVRELEHAIHRAVVLARATRAGDEVVLEEQHFALSEDVLPAPSAESFL
                     ALPACRNLRESTENFQREMIRQALAQNNHNWAASARALETDVANLHRLAKRLGLKD"
     gene            19019..20458
                     /gene="norV"
                     /locus_tag="OPY25_000918"
     CDS             19019..20458
                     /gene="norV"
                     /locus_tag="OPY25_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HCS0926587.1"
                     /translation="MSILVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRSEIDLADIDYIIINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFKVVKTGDTLDIGDGKQLIFVETPMLHWPDSMMTYMTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     NEVDPNVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDLDALELCRQHGRDI
                     ARQWALAPLPETTQKTAPVEETTTCTAADLGPKMQCSVCQWIYDPALGEPLQDVAPGT
                     PWSDVPDNFLCPECSLGKDVFDVLATEAK"
     gene            20455..21588
                     /gene="norW"
                     /locus_tag="OPY25_000919"
     CDS             20455..21588
                     /gene="norW"
                     /locus_tag="OPY25_000919"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HCS0926588.1"
                     /translation="MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKP
                     DLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTWVTDIDADAHVVKSQDKQWQYDK
                     LVLTTGATAFVPPIAGRELMLTLNSQQEYRACETPLRDAQRVLIVGGGLIGSELAMDF
                     CRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRA
                     TLVSQHSIEVDAVIAATGLRPETALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAE
                     INGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLS
                     WQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV"
     gene            complement(21685..23925)
                     /gene="hypF"
                     /locus_tag="OPY25_000920"
     CDS             complement(21685..23925)
                     /gene="hypF"
                     /locus_tag="OPY25_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HCS0926589.1"
                     /translation="MAIDTPSGVQLRIRGKVQGVGFRPFVWQLAQQLQLHGDVCNDGD
                     GVVVRLLEDPSQFIAALYQDCPPLARIDSVEHASLVWERAPTDFTIRQSAGGSMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ECDSEYRDPYDRRFHAQPVACPSCGPHLEWRSQHERAEKEAALQAAVAQLNAGGIIAV
                     KGLGGFHLACDARNDNAVAMLRARKHRPAKPLAVMLPTAQTLPTAARSLLTTPAAPIV
                     LVDKQYVPSLSEGIAPGLTEVGVMLPANPLQHLLLQALNYPLVMTSGNLSGKPPAITN
                     EQALDDLHDIADGFLLHNRDIVQRMDDSVVRDSGEMLRRSRGYVPDAIALPPGFRDVP
                     PILCLGADLKNTFCLVRGEQAVVSQHLGDLSDDGIQAQWREALRLIQSIYDFTPERIV
                     CDAHPGYVSSQWASEMRLPTETVLHHHAHAAACLAEHGWPLDGGEVIALTVDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPDWQNYPE
                     TAGLQQQNWSVLARAIERGVNAPLASSCGRLFDAVAAALRCAPASLSYEGEAACALEA
                     LASQCANVEYPVTMPLNGAQLDVAVFWRQWLNWQATPAQRAWAFHDALACGFATLMRQ
                     QATARGITTLVFSGGVIHNRLLRARLAFYLSDFKLLFPQRLPAGDGGLSFGQGVIAAA
                     RALREV"
     gene            complement(24071..24616)
                     /gene="hydN"
                     /locus_tag="OPY25_000921"
     CDS             complement(24071..24616)
                     /gene="hydN"
                     /locus_tag="OPY25_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HCS0926590.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNVSTATLCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVVRNSGAGLNVRAEKAEANKCDLCHHREAGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRAALDSTASLLF"
     gene            complement(24817..25626)
                     /locus_tag="OPY25_000922"
     CDS             complement(24817..25626)
                     /locus_tag="OPY25_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926591.1"
                     /translation="MLPGIGGKKNVKIIVWSGLLFLCLAARALATGVVGYLPMSDGEY
                     AQKRALKPLLILPYSVSPDQTWHFRQVGVSSVTLLPEPKKDNEWRISGKDRAGNSWVV
                     PVGRLINLAGNAQFYRADLDRNGIQDLVIWLGNPGLGLAPSAQYIIFTFLKNGRPCVF
                     EPWGFYTATDTGVDDLLDLQGNGRTQLLDMQFDSGYWITNLYQVKDARWQRVHGWFGR
                     LSYPALTRFNHYPGRKLIIKPIAGRNPQTDDLSLTQRCLIRGNVLPGVNQD"
     gene            complement(25653..26123)
                     /gene="hycI"
                     /locus_tag="OPY25_000923"
     CDS             complement(25653..26123)
                     /gene="hycI"
                     /locus_tag="OPY25_000923"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HCS0926592.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEMCAAQPKGNWVVIDGGSAPE
                     NDIVAIRELRPQRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDLLK
                     EDVGEVIFVGIQPDIVGFYYPMTQPIKDAVNIVYQRLEGWQGNGGFAALDAPEA"
     gene            complement(26116..26526)
                     /locus_tag="OPY25_000924"
     CDS             complement(26116..26526)
                     /locus_tag="OPY25_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase maturation HycH family
                     protein"
                     /protein_id="HCS0926593.1"
                     /translation="MSEQVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDEYLAWIATLEAGSDARRKMEGVPKYGEIVIDFNHVQMLARAFDEARAA
                     QTPQQQEWSKLMLSMLHDIHQESAIYLMVRRLRD"
     gene            complement(26523..27290)
                     /gene="hycG"
                     /locus_tag="OPY25_000925"
     CDS             complement(26523..27290)
                     /gene="hycG"
                     /locus_tag="OPY25_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HCS0926594.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKNIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARAPGELDDQPAEILHPDMVQPLRVKVDRAACRLAGYRYGRQIADDYLTQ
                     LGQGEQQVARWLEAENDPRLTEIVIHLNHVVEEARIR"
     gene            complement(27290..27832)
                     /gene="hycF"
                     /locus_tag="OPY25_000926"
     CDS             complement(27290..27832)
                     /gene="hycF"
                     /locus_tag="OPY25_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HCS0926595.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEHNPQQCIGCA
                     ACVNACPSNALTVETDLATNELAWQFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLAHNGDSRAENHRESFETCPDCKR
                     QKCLVPSDRIELTRHMKEVS"
     gene            complement(27842..29551)
                     /gene="hycE"
                     /locus_tag="OPY25_000927"
     CDS             complement(27842..29551)
                     /gene="hycE"
                     /locus_tag="OPY25_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HCS0926596.1"
                     /translation="MFEEKLGQQYLAALHQAFPGVVMDEAWQTKDQLTITVKVNYLPE
                     VVEFLYYQQGGWLSVLFGNDERQLCGHYAVYYVLSMEQGTKCWITVRVEVDANKLEFP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKEDMIQTRQLAQQMRRDVQELVDMLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTSLNMIDFGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(29569..30492)
                     /locus_tag="OPY25_000928"
     CDS             complement(29569..30492)
                     /locus_tag="OPY25_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory chain complex I subunit 1 family
                     protein"
                     /protein_id="HCS0926597.1"
                     /translation="MSVFYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSIAPADSGWVFRLTPFVMVGVMLTIATALPVVTVGSPLPQLGDLITLIY
                     LFAIARFFFSIAGLDTGSPFTAIGASREAMLGVLVEPILLLGLWVAAQVAGSTHISNI
                     ADTIYHWPVARSIPLILALCACAFATFIEMGKLPFDLAEAEQELQEGPLTEYSGSGFA
                     VLKWGISLKQLVVLQMFVGVFLPWGQMETFSAGGLLLALVIAVVKLIVGVLVIALFEN
                     SMARLRFCATSRVTWAGFGFAFLAFVSLLAA"
     gene            complement(30495..32321)
                     /gene="hycC"
                     /locus_tag="OPY25_000929"
     CDS             complement(30495..32321)
                     /gene="hycC"
                     /locus_tag="OPY25_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461772.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HCS0926598.1"
                     /translation="MSSLSLITSGVAWFAAAAVLAFLFSFHKALSGWIAGIGGAVGSL
                     CTAGAGFTALTSAVTVSGVMPFTGHMLQITPLNAIWLITLGLCGLFVSLFNIDWHRHP
                     QVKANGLLINLLMAAAVCAVVASNLGTMVVMAEIMALCAVFLTGGSKEGKLWFALGRL
                     GTLLLAIACWLVWQRYGTLDLGLLDQRAQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILSLSLLGGNAPLWWGVALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALNQPVLIALGLTGGLYHLLNHSL
                     FKSVLLLGAGSIWFRTGHRDIEKLGGIGKRMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLGNSGAFVGRLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ASCAPILMGVSVVALAVCCVLGGVAAPWLLPMISTAVPLPLETAHTTVSQPMITLLLV
                     ACPLLPFIIMAMFKGNRLPSRSRGAAWVCGYDHEQSMVITAHGFAMPVKEAFAPVLKL
                     RKWLNPVSLVPGWQNAAAAGLFRRLALIELAVLVVIVVSRGA"
     gene            complement(32321..32929)
                     /gene="hycB"
                     /locus_tag="OPY25_000930"
     CDS             complement(32321..32929)
                     /gene="hycB"
                     /locus_tag="OPY25_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HCS0926599.1"
                     /translation="MNRFVIVDSTLCIGCHTCEAACSETHRQHGLQSMPRLKVMLNEK
                     ESAPQLCHHCEDAPCATVCPVNAINRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLHIPANANTPKAPPAPPAPARVSTLLDWVPGVRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVENTDIARASKRKRELTFNTDFGDLTLFQQAQSGDA"
     gene            complement(33075..33536)
                     /gene="hycA"
                     /locus_tag="OPY25_000931"
     CDS             complement(33075..33536)
                     /gene="hycA"
                     /locus_tag="OPY25_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HCS0926600.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPERDLCFVLFEHFRIYVALADGFNSHTIEYYVETKDGEDKQLIAQAQLDIDGK
                     VDERVNNRDREQVLEHYLEKIASVYDSLYTAVETNSPVNLRQLVKGHSPAV"
     gene            33746..34102
                     /gene="hypA"
                     /locus_tag="OPY25_000932"
     CDS             33746..34102
                     /gene="hypA"
                     /locus_tag="OPY25_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HCS0926601.1"
                     /translation="MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSAL
                     SFCFDLVCRGTIAEGCKLHLEEQEAECWCEHCQQYVTLLTHRVRRCPQCHSDTLRIVA
                     DDGLQIRRIEIDETED"
     gene            34172..35044
                     /gene="hypB"
                     /locus_tag="OPY25_000933"
     CDS             34172..35044
                     /gene="hypB"
                     /locus_tag="OPY25_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HCS0926602.1"
                     /translation="MCTTCGCAEGNLYIEGDEHNPHSAFRSAPFAPAARPALNITGIK
                     TPDFTPSQTAEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     QQLVLNLVSSPGSGKTTLLTETLMKLKDRVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDHGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIASAREVNPEIEIILISATSGEG
                     MDQWLAWLEAQRCA"
     gene            35035..35307
                     /gene="hypC"
                     /locus_tag="OPY25_000934"
     CDS             35035..35307
                     /gene="hypC"
                     /locus_tag="OPY25_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HCS0926603.1"
                     /translation="MCIGVPGQIRAIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRL
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEER"
     gene            35307..36428
                     /gene="hypD"
                     /locus_tag="OPY25_000935"
     CDS             35307..36428
                     /gene="hypD"
                     /locus_tag="OPY25_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461778.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HCS0926604.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDSCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQ
                     AKQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPRARCGEVLTGRCKPH
                     QCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV"
     gene            36425..37435
                     /gene="hypE"
                     /locus_tag="OPY25_000936"
     CDS             36425..37435
                     /gene="hypE"
                     /locus_tag="OPY25_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="HCS0926605.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELA
                     QLTAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKSVVNSMAATAREAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPADIHWG
                     AQTLSVGDVLLVSGTLGDHGATILNLREQLGLDGELASDCAVLTPLIQTLRHIDGVKA
                     LRDATRGGVNAVAHEFAASCGYGIELSESALPLKPAVRGVCELLGLDALNFANEGKLV
                     IAVERQAADRALAALRAHPLGRDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            37654..39732
                     /gene="flhA"
                     /locus_tag="OPY25_000937"
     CDS             37654..39732
                     /gene="flhA"
                     /locus_tag="OPY25_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HCS0926606.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLSEALSQLVKRSALA
                     DSAGIVLWQAQSQRAQYYATRENGRPVEYEDETVLAHGPVRRILSRPDALHCNFHEFT
                     ETWPQLAASGLYPEFGHYCLLPLAAEGRIFGGCEFIRQEDRPWSEKEYDRLHTFTQIV
                     GVVAEQIQNRVNNNVDYDLLCRERDNFRILVAITNAVLSRLDINELVSEVAKEIHHYF
                     NIDAISIVLRSHRKNKLNIYSTHYLDEHHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     NERDPLAPYERMLFDTWGNQIQTLCLLPLMSGKTMLGVLKLAQCEEKVFTTANLKLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYNVL
                     KQVEMVAQSDSTVLILGETGTSKELIARAIHNLSGRSGRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KLIQTDVRLIAATNRDLKKMVADREFHNDLYYRLNVFPIQLPPLRERPEDIPLLVKAF
                     TFKIARRMGRNIDSIPAETLRTLSGMEWPGNVRELENVVERAVLLTRGNVLQLSLPDM
                     TAVTPDTSPVATESAKEGEDEYQLIIRVLKETNGVVAGPKGAAQRLGLKRTPLLSRMK
                     RLGIDKDALA"
     gene            complement(39794..40138)
                     /locus_tag="OPY25_000938"
     CDS             complement(39794..40138)
                     /locus_tag="OPY25_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HCS0926607.1"
                     /translation="MPGKRIAREKLTIKKMIALYESQCPQASAVQGHYDALFAYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPVLTVRHLIDDKRP
                     VPELPEKYQRKK"
     gene            40320..41237
                     /gene="sitA"
                     /locus_tag="OPY25_000939"
     CDS             40320..41237
                     /gene="sitA"
                     /locus_tag="OPY25_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter substrate-binding
                     protein SitA"
                     /protein_id="HCS0926608.1"
                     /translation="MTNLHRLKTLLIAGIVAILALSPAYAKEKFKVITTFTVIADMAK
                     NVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGLNLERWFARFYQHLSG
                     VPEVVVSTGVKPMGITEGPYNGKPNPHAWMSAENALIYVDNIRDALVKYDPDNAQIYK
                     QNAERYKAKIRQMADPLRAELEKIPADQRWLVTSEGAFSYLARDNDMKELYLWPINAD
                     QQGTPKQVRKVIDTIKKHHIPAIFSESTVSDKPARQVARESGAHYGGVLYVDSLSAAD
                     GPVPTYLDLLRVTTETIVNGINDGLRSQQ"
     gene            41234..42055
                     /gene="sitB"
                     /locus_tag="OPY25_000940"
     CDS             41234..42055
                     /gene="sitB"
                     /locus_tag="OPY25_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter ATP-binding
                     protein SitB"
                     /protein_id="HCS0926609.1"
                     /translation="MSQSAITVDQVTVTYRNGHTALRDATFQVPGGSIAALVGVNGSG
                     KSTLFKALMGFVHLARGDITILQQSVNQALKKNLIAYVPQSEEVDWSFPVLVEDVVMM
                     GRYGHMGWLRRPTAHDHACVDAALARVDMQEYRHRQIGELSGGQKKRVFLARAIAQDG
                     QVILLDEPFTGVDVKTEARIIDLLRELRDEGRTMLVSTHNLGSVTEFCDYTVMIKGTV
                     LASGPTETTFTAANLELAFSGVLRHIALSGGEEHIITDDERPFISRRVASGGKSS"
     gene            42052..42912
                     /gene="sitC"
                     /locus_tag="OPY25_000941"
     CDS             42052..42912
                     /gene="sitC"
                     /locus_tag="OPY25_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitC"
                     /protein_id="HCS0926610.1"
                     /translation="MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGD
                     ALSHSIVPGVAGAWMLGLPFSLGAFLSGGLAAGSMLFLNQRSRLKEDAIIGLIFSSFF
                     GVGLFMVSLNPMSVNIQTIILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFF
                     DETHARSIGLNPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFP
                     RLLMIAVVIGSLTSFLGAWLSYWLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRR
                     ARLQKEPTCS"
     gene            42903..43751
                     /gene="sitD"
                     /locus_tag="OPY25_000942"
     CDS             42903..43751
                     /gene="sitD"
                     /locus_tag="OPY25_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitD"
                     /protein_id="HCS0926611.1"
                     /translation="MFLATLLEPFQFDFMVNALMVSVIVAIPCALLSVFLVLKGWALM
                     GDAMSHAVFPGVVLAYIVGIPLAIGAFIAGLFCAIATGYLDDNSRIKRDTVMGIVFSG
                     MFGAGLVLYVSIQSEVHLDHILFGDMLGVSLGDIVQTSVIALGIALIIGLKWKDLLLH
                     AFDPHQAKASGLNTTLLHYGLLCMIALTIVATLKSVGIILSISLLIAPGAIAILLTRR
                     FARALGLAVSLSVITAFAGVYLSFYLDSAPAPTIVVLFAIVFIAVFIYATWRDRRNEI
                     VPEAQG"
     gene            complement(44028..44783)
                     /locus_tag="OPY25_000943"
     CDS             complement(44028..44783)
                     /locus_tag="OPY25_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCS0926612.1"
                     /translation="MRNVIIYGINWTNCYALQSIFKQKYPEKCVKTCNSLTALLHSLS
                     DMPDAGLILALNPHEHVYLFHALQARLQNRKVLVVADRLYYIDRCVLQYFGVMDYVLK
                     DELSCAIRSEREKLRLPEAWLRFCHRPQKKTVAATYAFNAGETPEEVLFNINQYAWWN
                     LPPGVTQAKYALLILLSSGHPAIELAKKFGLGTKTVSIYRKKVMYRLGMDSSPLSLFR
                     GLKLDAHLQRTAFAHNPAVPDDNCALPIAVGMN"
     gene            complement(45168..46055)
                     /gene="sirC"
                     /locus_tag="OPY25_000944"
     CDS             complement(45168..46055)
                     /gene="sirC"
                     /locus_tag="OPY25_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SirC"
                     /protein_id="HCS0926613.1"
                     /translation="MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLF
                     KLNKGSLRIENEFGEFIEQSALCLFLLEKDQTITLSMSEIEGHIDFSSLEVSYDLMQK
                     FYKVFYSTRNYNDRELSLKTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDD
                     HDYSYFSLMYLISAFVRKPGGFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKL
                     FMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIA
                     IFKRHFKITPLSFMRTMNH"
     gene            complement(46401..46853)
                     /locus_tag="OPY25_000945"
     CDS             complement(46401..46853)
                     /locus_tag="OPY25_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector protein OrgC"
                     /protein_id="HCS0926614.1"
                     /translation="MIPGTIPTSYLVPTADTEVTGVVSLSARAAMLNNVDSAPLSNGG
                     DVDLYDAFYQRLLALPESASSETLKDSIYQEMNAFKDPKSGDSAFVSFEQQTAMLQNM
                     LAKVEPGTHLYEALNGVLVGTMNAQSQMTSWMQEIILSGGENKEAIDW"
     gene            complement(46869..47540)
                     /gene="orgB"
                     /locus_tag="OPY25_000946"
     CDS             complement(46869..47540)
                     /gene="orgB"
                     /locus_tag="OPY25_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system linker protein OrgB"
                     /protein_id="HCS0926615.1"
                     /translation="MLKNIPIPSPLSPVEGILIKRKTLERYFSIERLEQQAHQRAKRI
                     LREAEEEAKTLRMYAYQEGYEQGMIDALQQVAAYLTDNQTMAWKWMEKIQIYARELFS
                     AAVDHPETLLTVLDEWLRDFDKPEGQLFLTLPVNAKKEHQKLMVLLMENWPGTFNLKY
                     HQEQRFIMSCGDQIAEFSPEQFVETAVGVIKHHLDELPQDCRTISDNAINALIDEWKT
                     KTQAL"
     gene            complement(47497..48096)
                     /gene="orgA"
                     /locus_tag="OPY25_000947"
     CDS             complement(47497..48096)
                     /gene="orgA"
                     /locus_tag="OPY25_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-regulated invasion protein OrgA"
                     /protein_id="HCS0926616.1"
                     /translation="MIRRNRQMNRQPLPIIWQRIIFDPLSYIHPQRLQIAPEMIVRPA
                     ARAAANELILATWRLKNGEKECIQNSLTQLWLRQWRRLPQVAYLLGCHKLRADLARQG
                     ALLGLPDWAQAFLAMHQGTSLSVCNKAPNHRFLLSVGYAQLNALNEFLPESLAQRFPL
                     LFPPFIEEALKQDAVEMSILLLALQYAQKYPNSVPAFAC"
     gene            complement(48068..48826)
                     /gene="prgK"
                     /locus_tag="OPY25_000948"
     CDS             complement(48068..48826)
                     /gene="prgK"
                     /locus_tag="OPY25_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner membrane ring
                     lipoprotein PrgK"
                     /protein_id="HCS0926617.1"
                     /translation="MIRRYLYTFLLVMTLAGCKDKDLLKGLDQEQANEVIAVLQMHNI
                     EANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPRPRVEIAQMFPADSLVSSPRAEK
                     ARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALAVYERGSPL
                     AHQISDIKRFLKNSFADVDYDNISVVLSERSDAQLQAPGTPVKRNSFATSWIVLIILL
                     SVMSAGSGVWYYKNHYARNKKGITADDKAKSSNE"
     gene            complement(48823..49128)
                     /gene="prgJ"
                     /locus_tag="OPY25_000949"
     CDS             complement(48823..49128)
                     /gene="prgJ"
                     /locus_tag="OPY25_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner rod protein
                     PrgJ"
                     /protein_id="HCS0926618.1"
                     /translation="MSIATIVPENAVIGQAVNIRPMETDIVSLDDRLLQAFSGSAIAT
                     AVDKQTITNRIEDPNLVTDPNELAISQEMISDYNLYVSMVSTLTRKGVGAVETLLRS"
     gene            complement(49147..49389)
                     /gene="prgI"
                     /locus_tag="OPY25_000950"
     CDS             complement(49147..49389)
                     /gene="prgI"
                     /locus_tag="OPY25_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle filament
                     protein PrgI"
                     /protein_id="HCS0926619.1"
                     /translation="MPTSWSGYLDEVSAKFDKGVDNLQTQVTEALDKLAAKPSDPALL
                     AAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR"
     gene            complement(49414..50592)
                     /gene="prgH"
                     /locus_tag="OPY25_000951"
     CDS             complement(49414..50592)
                     /gene="prgH"
                     /locus_tag="OPY25_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner membrane ring
                     protein PrgH"
                     /protein_id="HCS0926620.1"
                     /translation="METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSD
                     ALTASGQLPDIPADSFFIPLDHGGVNFEIQVDTDATEIILHELKEGNPESRSVQLNTP
                     IQVGELLILIRPESEPWVPEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTL
                     WILNSPQRQAAELDSLLGQEKERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDK
                     NARVINENEENKRISTWLDTYYPQLAYYRLHFDEPRKPVFWLSRQRNTMSKKELEVLS
                     QKLRALMPYADSVNITLMDDVTAAGQAEAGLKQQALPYSRRNHKGGVTFVIQGALDDV
                     EILRARQFVDSYYRTWGGRYVQFAIELKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL
                     "
     gene            50908..51837
                     /gene="hilD"
                     /locus_tag="OPY25_000952"
     CDS             50908..51837
                     /gene="hilD"
                     /locus_tag="OPY25_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator HilD"
                     /protein_id="HCS0926621.1"
                     /translation="MENVTFVSNSHQRPAADNLQKLKSLLTNTQQQIKSQTQQVTIKN
                     LYVSSFTLVCFRSGKLTISNNHDTIYCDEPGMLVLKKEQVVNVTLEEVNGHMDFDILE
                     IPTQRLGALYALIPNEQQTKMAVPTEKAQKIFYTPDFPARREVFEHLKTAFSCTKDTS
                     KGCSNCNNKSCIENEELIPYFLLFLLTAFLRLPESYEIILSSAQITLKKRVYNIISSS
                     PSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAV
                     ALKCGYDSTSYFIQCFKKYFKTTPSTFIKMANH"
BASE COUNT        12524 a        14372 c        13259 g        12138 t
ORIGIN      
        1 tatttatgat ttttagttta tgtgatcaat acactctggc atcgtgagtt atccgccttt
       61 tctgtttacc agatcacatt ttattattta acaggccagg cattacttaa tttaaaatgt
      121 attctcgccg caaatataat aaacgcaaat tatattaagc aataaaaaac cccggccata
      181 aaccggggtt aatttaaata ctggaaccgc ttaccaataa gactaaatat gcaattcctg
      241 cagtttttct ttcggcagcg ccagctcttt attgctgttc acgcgcacat cacgctccag
      301 aatatgacgg gcaatgtcct gcgcttcact gagcgagtgc atctgatacg taccgcactg
      361 gtaaacgttc agctccggga tctggttttg atcctgcact ttcagcacat ccgccatcgc
      421 cgctttccaa gcgtcggcaa cacgctgctc gtccggcgtg ccaatcaggc tcatgtaaaa
      481 gccggtgcgg cagcccatcg gcgagatatc gataatctca acgccgttac cgttgaggtg
      541 gtcgcgcata aagccagcaa acagatgctc aagcgtatga atcccttttt ccggcatcac
      601 ttctttgttc ggaatgcaaa aacgcagatc aaacacggtg attgcgtcgc catgcggggt
      661 gttcatcgtt tttgcaaccc ggaccgccgg cgcttgcatc cgggtatgat cgactgcgaa
      721 gctatctaat aatggcattt agtcacctcc gataattttt taaaaataaa ctgaactctt
      781 tgttccgggg cgagtctgag tatatgaaag acgcgcattt gttatcatca tccctgtttt
      841 cagcgatgaa attttggcca ctccgtgagt ggcctttttc ttttgggtca ggcgtgtttc
      901 gcaagccacg cggcaaacgg ctcggtatcc gccgcctcaa tctcctgctg acgacgtact
      961 gaagcgtcac gttcagcaat aaactcttct tcctgtaaaa tctccagcgg ctcttcgcgt
     1021 aacagattac ggtaagcctc accgaacgct ttcccagtgc cgccaatgcc ttcatcaatc
     1081 atagaccgta agattcgggc agagaatgtc agttcaggat tatcaaagca ggcgaccaac
     1141 tcatcacaca ccttttgata ctcctctccc ccgtggatac tgtccagcgt ttgcgccacg
     1201 cgtttcagat cgcggaagag atctttccct actttaggca gcgggaactg cgcggtttca
     1261 cagccaatcc ccagggtaag gcccggctta cgcccttcca gaataacgcg attccagtta
     1321 gtacgcgtac ataacagctc atcgctactc atttccggcg catcggccaa tacgcaccag
     1381 accataaaca gatcgaggaa gcgcacctgt tgctcgtcta cgccgatcgg tgagaacgga
     1441 ttaatatcga gagaacgaac ttcgatgtac tcaataccac cacgcagaag cgcatctgaa
     1501 ggcgattcgc cgctgcgcgt cacgcgcttg ggacgaatgg gcgcgtacag ctcattttca
     1561 atttgcagaa cgttgctgtt aatctgtagc cgcttaccgt ctttttccac accaatccgc
     1621 gcgtactctt ctgacggcgt tttaatcgcc cgtttcagac ctgcaacgta ttcatgtaga
     1681 tcgttaaacg taatacccag attgctttgc gacttattgg tatagcccaa atcactcaaa
     1741 cgcagcgacg tcgcatatgg caggtagtac atgccgcagt ccgttttttc aaacggtaat
     1801 gtggttggct tcccttgcag gaaagaggaa caaatggccg gagacgcgcc aaacagatag
     1861 gggatgaccc agccaaaacg gtaatagttg cgaatcagac gaaaatagcc ggcagaaatt
     1921 ttttcttttg ccgcttcgcc ttccgtaacg ccgcatttcg cctgccagaa cgccatcggt
     1981 aatgaaaaat tgtaatgtac gccggaaatg gtttgcatca aagcgccata acgatttttc
     2041 agcccttcgc gatagagcgt cttaaagcgc ccggtatttg atgtgccgta ctgcgccagc
     2101 tctatgtcct gcccttccgc aatatagcag ggcatactta atggccacat ccgctcatcg
     2161 cccagtttcc tggccgtata ccgatggaga tcgcgcataa aggtgagcat atgctggata
     2221 tcgccatcga ctggcgtaat aaactccagt agggcttccg caaaatctgt ggtaatccat
     2281 ttatgggtca gcgctgaacc taacgcttca ggatgaactg ttgtcgccag cgtgccatca
     2341 gcattgacac gcagcgtttc gcgctctaac ccgcgctgta tcccctttaa cgcctgagga
     2401 tgtttttcca gccaggccag agcctgtgat acgtccggga tcaaattgac ctcccgcctg
     2461 tccaaatcgt tttaataagc ataactgtaa tggcggccat acatgccaaa cctacaatta
     2521 ttaccaccac atcatgccct gaaccgtcgc cgctgcgagc gcaacatagc gcagcgcctt
     2581 accaagacac aaaaaaaaga tcgtccgccc ccacgggatg cgcatccatc ccgctaacag
     2641 gcacaacaaa tcaccgatga ccggcatcca gcttaataat agtgtggctg cgccataacg
     2701 ctttagccag ccagtcgctt tttcctgcca acgcgacgtt ttgcgcagcg gaaagaaacg
     2761 cccaagaata acgttagtta cccctccaag gctattaccc attgttgctg ttaagactaa
     2821 gacccaggga tgactgacgc cggagaccag catagcaacc aaaaccacct cagaattacc
     2881 gggtaacagc gtcgcgctga gaaaactact ggcaaacaga gacaggagcg acagtccgtc
     2941 actcacaata gtcggacatc cacggcatcc attcccgccg cccgcgccgc ctgtaaacca
     3001 aaatcggcat cttcaaatac cacgcactgc gtcggcatga cgcccatccg ctgggcgcac
     3061 aataggaagg tgtcaggcgc aggtttgtga tgctgtacgt gatctgccgc cacaaccgca
     3121 tcaaaataac gacgcagccc cagatgcgct aacaaggctt ccgcgatagc gctttcgcta
     3181 ccggtaccga ccgacatggg acgccgccca tgccacgctt tgaccacctc aaccagcggc
     3241 agcggttcta cgcagtccag caggatgctt tttaccgcgt cggttttctc acgcgccagt
     3301 gacaggggat caagatcggc atggttaagc tcaatgattg actgggcgat aagccaggtt
     3361 ggcgaaccgt taagcgcgac cattgcctgt tcatcaaaac gaagaccata gcgccccaaa
     3421 acctcacgcc acgctttgcg atgcgtgggt tcggtatcca ggagagtacc gtccatatca
     3481 aaaatcaaac cagcataacg tgcgtacatc gtgttctcgc aaaccgaata accagacagt
     3541 actttatcgc aattggttga ttttgtcgct aatagagatg aagaggtata ttcaggataa
     3601 gggggaaaag cgattgcagg gcagtaacgt atccgggagg attactcgcc cttcgggccg
     3661 ttgctgatgc aacgttatcc ttctgatgcc agcggtgatt accgctatct tatctgcatc
     3721 ttcatcgctg aaagtatgga gaatatggtg catccgggag gattactcgc cttacggctc
     3781 gcccttcggg ccgttgctga cgcaacgtta tccttcctgg tgcctgcggt gattaccgct
     3841 atcttatccg catctttatc gctgaaagta tggagaatat ggtgcatccg ggaggattcg
     3901 aacctccgac cgctcggttc gtagccgagt actctatcca gctgagctac ggatgcattg
     3961 ggaaacttgc tttactgctg atattgatac cgcggtgaaa gccgtatcaa ttaagagatg
     4021 gtgtatccgg gaggattact cgccttacgg ctcgcccttc gggccgttgc taacgcaacg
     4081 ttatccttcc tggtgccagc ggtgattacc gctatcttat ccgtatcttc atcgctgaaa
     4141 gtacggagaa tatggtgcat ccgggaggat tcgaacctcc gaccgctcgg ttcgtagccg
     4201 agtactctat ccagctgagc tacggatgca tcggaaaact tgctttactg ccgatattga
     4261 taccgcggtg aaagccgtat caagtaagag atggtgcatc cgggaggatt cgaacctccg
     4321 accgctcggt tcgtagccga gtactctatc cagctgagct acggatgcat cgggaaactt
     4381 actttactgc agattttgat accgcggtga aagccgtatc aagtaagaga tggtgcatcc
     4441 gggaggattc gaacctccga ccgctcggtt cgtagccgag tactctatcc agctgaagct
     4501 acggatgcaa atggcggtga ggcggggatt cgaaccccgg atgcagcttt tgaccgcata
     4561 ctcccttagc aggggagcgc cttcagcctc tcggccacct caccacacgc ctcttacgag
     4621 tgcttcgaag aacttgttct gctcatcgtc gctgcgtggc gcacatatta ctttctggga
     4681 cttataagtc aaacaatttt tccagagctt ttatcgtttg cacacttcac gctcaattag
     4741 tctataaaaa agccaaaaag agtgttttat caacagataa tttgatgaca cgctggccgc
     4801 caaaagcgca ccatatcaac agtgaggttg aaaaaagtca tgaggggaca acgcgggcga
     4861 gcgagaagag aggctgcgtc tcacccgaaa agtgagacgc gaaaacctta gtaactggac
     4921 tgctgggatt tttcagcctg gatacgctgg tagatctctt cacgatggac agaaacttct
     4981 ttcggggcgt tcacgccaat acgcacctgg ttgcccttca cccctaaaac tgtcacggtg
     5041 acctcatcgc caatcatgag ggtctcacca actcgacgag tcagaatcag cattctttgc
     5101 tccttgaaag attaaaagag tcgggtctct ctgtatcccg gcattatcca tcatataacg
     5161 ccaaaaagta agcgatgaca aacaccttag gtgtaagcag tcatggcatt acattctgtt
     5221 aaacctaagt ttagccgata tacaaaactt caacctgact ttatcgttgt cgatagcgtt
     5281 gacgtaaacg ccgcagcacg agctgcggcg ccaacgaacg cttataatta ttgcaatttt
     5341 gcgctgaccc agccttgtac actggctaac gctgcaggca gagctgccgc atccgtacca
     5401 ccggcttgcg ccatgtccgg acgaccgcca cccttaccgc ccacctgctg agcgaccata
     5461 ccaatcaatt cccctgcttt aacccggtcg gtcacatcct tcgacacgcc cgcaatcaga
     5521 gaaaccttac cttcaacaac cgttgccagt acgataacgg tagaccccag ttgatttttc
     5581 agatcatcaa ccatggttcg cagcattttc ggctcaatac cagcaagctc gctgaccagg
     5641 agcttcacgc cgttgagatc gaccgcttta ctggaaagat ttgcactctc ctgcgctgcg
     5701 gcctggtcct tcaactgctg caactctttt tccagctgac gcgtacgttc cagcacggca
     5761 cgcactttgt cgcccagatt ctggctgtcg cccttcagca gatgcgcaat atcgtttaag
     5821 cgatcgcttt gcgcgtgaac ggtggccata gcgccttcac cggttaccgc ctcaatacga
     5881 cgaatgcccg ctgcggtgcc ggactcagag ataatacgga atagaccgat atcaccggta
     5941 cgactggcgt gagtaccgcc gcacagttcg gtagagaaat cgcccatgct cagaacgcgt
     6001 acacgttcgt cgtatttctc gccaaacagc gccatggccc ctttcgcctt cgccgcgtcg
     6061 agatccatga tgttcgtttc aatcggcagg ttgcggcgaa tttgcgcatt caccaaatct
     6121 tcaacctcac gaatctccga cggcttcatc gcttcattgt gcgagaagtc gaagcgcagc
     6181 actttatcgc taaccagcga acctttctgc gcaacgtgtg tcccaagcac ctggcgcaac
     6241 gccgcgtgca tcaggtgcgt ggcggagtgg ttcagacgga tacgtgcgcg gcgcgcttca
     6301 tctacgtcag cctgtaccgc atcgcccact ttcagagcgc ccgcagacaa tttgccgagg
     6361 tgaccaatcg cctgaccata tttttgcgtg tcgtccacag cgaaagtaaa tccagcgcct
     6421 ttcagctcgc ctttatcgcc aacctgaccg cctgattccg catagaatgg ggtctgatcc
     6481 agcacgacaa cagcttcctg tcccgcgtta atcgcttcaa ccgctttacc atcgacaaac
     6541 agcgcagtca ctttgccgtt cagttccaga tggtcataac ctttaaattc agaagcgctg
     6601 tcaacgcgga tcatcgcgtt gtagtccgcg ccaaaaccgc tagcttcgcg cgcgcgacgg
     6661 cgttgctctt ccatggcggc ttcaaaaccg gcttcgtcga ctttgatgtt gcgctcacgg
     6721 cagacgtccg ccgttagatc gaccgggaaa ccataagtat catacagacg gaaagcggtt
     6781 tcgccgtcca gggtgtcgcc ctgcaatttc gccagttctt catccagcag cgccagaccg
     6841 cgctccagcg tacgagcgaa ctgctcttct tccgttttca gaacctgctc gacctgcgcc
     6901 tgctgacgtt tcaactcttc gcctgcggag cccattacct caatcagcgg cccaaccagc
     6961 ttgtagaaga aggtctcttt tgcgcccagc atgttgccgt gacgaaccgc gcgacgaata
     7021 atgcgacgca gcacatagcc acggttttca ttcgacggca gcacgccatc ggcaaccagg
     7081 aatgcgcaag aacggatgtg gtcggcgata acgcgcagcg atttattacc caaatcggtg
     7141 gagccggtga ctttcgctac cgcttcaatc aacgtgcgga acaggtcgat gtcatagtta
     7201 gagttaacgt gttgcagtac cgcggcaata cgctccagcc ccataccggt atctacagac
     7261 ggtttcggca atggttccat cgtcccgtca gcctgacggt tgaactgcat aaagacgatg
     7321 ttccagattt caatatagcg atcgccgtct tcttccgggc ttcccggagg gccgccccag
     7381 atgtggtcgc catgatcgta gaagatttcg gtgcacggac cgcagggacc ggtgtcgccc
     7441 atctgccaga agttatccga tgcgtatggc gcgcctttat tgtcaccgat acggatgata
     7501 cgctcgcgcg ggatgccgac ttctttttcc cagatctcat aggcttcgtc gtcggtttca
     7561 tagacggtga cccataagcg ctcttttggc agagcaaacc agttttcgcc ggtcagtaat
     7621 tcccatgcga actgaatggc gtcgtgtttg aaataatcgc cgaagctgaa gttgcccagc
     7681 atttcgaaga aagtatggtg acgtgcagtg tatccgacgt tttccagatc gttgtgttta
     7741 ccccccgcgc gtacgcaacg ctgggaagtg gttgcacggg aataattacg tttatcgagc
     7801 ccaaggaaaa catccttgaa ctggttcatc ccggcattgg taaacaacag agtggggtca
     7861 ttgttaggca ccagggaact gctggcaact acctgatgcc ctttactatg gaaaaagtcg
     7921 agaaacgcct gacggatctc agcggtgctc ttgctcataa ttatcctgaa atcaagctac
     7981 actccatcct tcaggccgcc tctgcgttgg ctgcgagttt cccggtcacg cgttctcgag
     8041 gctcacttgc cgctttaatg cggcttgaat gattttgtgt atttaaggaa tattcgtcgc
     8101 agacgctgtt cgccgttaag caacccgcgt ccagacggaa aaagtgggaa taagataagt
     8161 tttctttacc gggaagtaaa atcccgtatg cgctcaatct gcaaaatttc gccatatttg
     8221 ctggatatcg tccatcagat acccgcgata gagcaaaaag cgctgtacct taaccttttc
     8281 tgaaaagttt gaagggagcg gctcgccata tttgcgaacg gcctgttcac gtgccatttc
     8341 actccagtca atttcacatt ctcgcatcgc tttttcagtc gattcacggg aaatgccttt
     8401 ctgattcaac tcctggcgaa tacgcgccgg gccatagcct ttgcggctac gactggcgat
     8461 aaagcgcatc acgaagcgct cgtcatcaag atagtggtgt tcgtggcacc aggcgatcac
     8521 gcgttcataa tcgtctgccg tcgcatcaat ctcttccggc ccatttttgc ccatcaccgg
     8581 cgcggagagt ttacgccgta gttcctgctc gctgtgatcg cggacagcaa gaatacgtac
     8641 cgcacgatca aggagacgag cataagcggg acggcgcgat gtgggttcac tcataaaaaa
     8701 ccttaacagg ggtaaatgcc aaaagggccg cataaatgca gcccttgatg gtaatttaac
     8761 gttttgctga atggcggctt cgttttgtcc gacccaccat cacctgatga ttaaaaatct
     8821 tcgttggttt ctgcaacgcc ttcgctatcg tcaacggcga aatcgggcgt ggcattctga
     8881 ttactcaaca gtaattcacg cactcttttc tcgatctctt tcgctgttgc cgggttctct
     8941 ttcagccagg tagtcgcgtt cgctttaccc tggccaatct tctcgccgtt gtagctgtac
     9001 catgcgcccg ctttctcgat cagcttctct ttcacgccca ggtcaaccag ttcgccatag
     9061 aagttgatgc cttcgccgta gaggatctgg aactcggcct gcttaaacgg cgcggcgatt
     9121 ttgtttttca ccactttcac acgcgtttcg ctacccacga cattatcgcc ttctttcacc
     9181 gcgccaatac gacggatatc aagacgaacg gaggcgtaga atttcagcgc gttaccgccg
     9241 gtggtggttt ccgggttacc aaacatcacg ccaattttca tacggatctg gttgatgaag
     9301 atcagcagcg tattggactg tttcaggttc cccgccagct tacgcatcgc ctggctcatc
     9361 atacgcgccg cgaggcccat gtgagagtcg ccgatttcgc cttcgatttc cgctttcggc
     9421 gttagcgccg ctacggagtc gaccacaatg acgtccaccg cgcctgaacg cgccagcgcg
     9481 tcacagattt ccagcgcctg ctcgccggta tccggctgag aacagagcag gttatcgata
     9541 tcgacgccca gcttgcgtgc gtaaacaggg tcaagcgcgt gttccgcatc gataaacgca
     9601 caggttttac cttcacgctg cgcagcggca atcacctgca gcgtcagggt cgttttaccg
     9661 gaagattccg gcccgtaaat ttcgacgata cgccccatcg gcagaccgcc cgcaccgagt
     9721 gcgatatcca gtgaaagcga accggtggag atagtttcca catccataga acggtcttca
     9781 cccagacgca tgatggagcc tttaccaaat tgcttttcaa tttggcccag tgctgccgcc
     9841 aacgctttct gtttgttttc gtcgatagcc attattactc ctgtcatgca acttggtatt
     9901 gaaccggata gtgaattcgt actgttgaag caattatact gtatgctcat acagtatcaa
     9961 gtgttttgta gaaattgttg ccacagggtt tgtagcgcgt atgtcgtcgc ctgtcgacgc
    10021 accgattcac ggtcgccgct gaagcattcc cgacgcgtaa tcccttctcc actgacgctg
    10081 gcgaaagcaa accacaccgt accaaccggc ttttcttcac tgccgccatc cggcccggca
    10141 atcccgctaa tagcgacagc aaaatcggcg cgagcggcct tcagcgcccc gatcgccatt
    10201 tcgaccacta cggattcgct gaccgcgcca tgctgcgcca gcgtctcttc acgcacgcca
    10261 atcatctgcg ctttggcttc attactatag gtgacaaagc cgcgttcaaa ccaggcggaa
    10321 cttccggcga tgtcggtaat ggctttcgcc agccagccgc cggtacagga ctccgctgtc
    10381 gttacggtcg ccccgcgcgc ttttaacgcc agcccgacct gttcgctaag ccgcatcagt
    10441 tcactgtcag tcatcatgac ctctgtcagt tagaaatcct gccgcacaag atagcacttt
    10501 ctcaccagag atggggacga gctgtcgatt ttacgagtcg gattccgaaa aaatgccagc
    10561 aggttattta tgcagaatga aagaggtagc acatgactaa atagcagtac tatgtcgcta
    10621 aatttacacg cacggagaga aagcaaggat gtcactcaaa aaaacggaaa gcgcacagca
    10681 caaactgaaa caaacctgtc aactacggct gtggttaatt gtgggtggag tatgttcatt
    10741 aggaatggga gtactgaata tattgtcgtc aggctatttt gaaccgtatg acggcggtca
    10801 aattatctta ggcctgggat gtctgggtta tagtctggca ctatcaaaaa agatatccca
    10861 cttgcaagcc caaaaagcca tagtaatagc ggaggggggc tcccctccct aagcgtaaat
    10921 tagcgcaccc gcgccagcgc taccgcctgc cccagttgcc aaaccgccat cgcataatgc
    10981 gtgctgtggt tatatcgggt aatggtgtag aagttcggca ggccgtacca gtactggtat
    11041 cccgtaccga tatccagacg cagcaggctg gcttcctgat gattgcccaa cgattgctgc
    11101 ggcgttaagc ctgcggcggc aagctgagag atgctgtatt ttgttttgaa accattcgcc
    11161 aacccaggcg cctgaccact cgccggcacc gcaaccatat cgcctttcac ccaaccatgc
    11221 gccttgaaat agttcgccac gctgccgatg gcatctaccg gatcccacaa gttaatgtgc
    11281 ccatcgccat tgaaatcgac cgcatattct ttataggaag acggcataaa ctggccgtag
    11341 cccatcgcgc cggcaaagga acctttcaga ttgagcggat cgtcttgctc atcgcgcgcc
    11401 atgagcagga aggtttccag ctcgccggag aaatattccg cccggcgcgg atagttaaat
    11461 gacagcgtcg ccagcgcgtc cagaatccgt gttttcccca tgatacgtcc ccagcgggtt
    11521 tccacgccga tgatgcccac aatgatttcc ggcggtacgc cgtatacctg ccaggcgcgg
    11581 ttcagcgcgt cttcatactg attccagaac gcgacgccgt tttgcacgtt atccggcgta
    11641 ataaattgtt tgcggtagcg caaccaggcg ccatttggtc cggcgggcgg ctgagtggtc
    11701 ggcgcttgtc tgtccatcag acgcagaacg taatccagtc ttttagactg cgagaggatc
    11761 tcttgcagct gctgacggtc gaaaccgtgt ttactgacca ttttatcaat gaactgctgc
    11821 gcattagggt tgttggcgaa gtcgccgccc atttgcatga cgttatgctg cggctcaagc
    11881 aggaagccgc cggaaggcgt gcccgtcgtc gcttgagtct cggaagattt tggcgtgctg
    11941 ctacaggcag caagcaatac gcaaagtgga agtaacgcta cataacgacg cttgaacatg
    12001 agacatccat taaacaaatt cagccaggga gaagtatggt aaagcatccc cccgccgcac
    12061 aaggaagcgg cacaagagaa taaatcacct ttcccctctc tccagtttgt atctgctcct
    12121 ccactccctc aatctttcaa gttaaaatat ttttctttta ttttgagatc aaaataacac
    12181 ttttatacct ttcaacatga ttacaatgag caggaagtta gcaagaaaac taaaaaccct
    12241 acaggagaga acaatgatcg aaaccattac acatggtgcg gagtggttca tcgggttatt
    12301 ccagaaaggc ggtgaggtgt ttaccggtat ggtgacaggt attcttccgc tactgataag
    12361 cctgctggtt atcatgaatg cgctcatcaa ttttatcggc cagcagcgta ttgagcgttt
    12421 tgcccaacgc tgcgccggaa atccgctatc ccgctacctg cttttaccgt ttatcgggac
    12481 gtttgttttt tgtaatccga tgaccctgag tctgggacgc tttatgccgg agaagtacaa
    12541 gccgagctat tacgcggcgg cctcctatag ctgtcactcc atgaacggtc tgtttccgca
    12601 tatcaatccc ggcgaactgt ttgtttatct gggtatcgcc agcggactca ccacgttagg
    12661 gcttcctctc ggcccgctcg cggtgagcta tctgctggta ggtctggtga cgaacttctt
    12721 ccgcggttgg gtcaccgatc tcaccaccgc tatttttgag aaaaaaatgg ggattcaact
    12781 tgagcagaaa gttcatctga caggagcggt atcatgacac gggttcgcat tgagaaaggt
    12841 gccggcggct ggggcggccc gcttgaactg gacgttacgc caggcaaaaa gatcgtctat
    12901 atcacagccg gtacgcgccc ggcgatcgtc gacaaactgg cgcaactaac aggctggcaa
    12961 gcggtggacg gctttaaaga aggcgaaccg ccggaagcgg agatcggcgc ggccattatc
    13021 gactgcggcg gtacgctgcg ctgcggtatc tacccgaaac gccggattcc aaccattaat
    13081 attcactcga cgggtaagtc cggcccactg gcgcagtata ttgttgaaga tatttatgtc
    13141 tccggcgtaa aagaagaaaa cattactcta gtcggcgaaa catctgccag accccagcct
    13201 gccaaaacga cattaggacg tgactacgac accagcaaaa aaatcaccga gcagagcgac
    13261 gggctgctgg caaaagtcgg tatgggaatg ggttctgccg tggcggtact gttccagtcc
    13321 ggtcgcgaca ccattgatac ggtcctgaaa acaattctgc cgtttatggc gttcgtttcg
    13381 gcgctaatcg gcatcattat ggcctcaggt cttggcgact ggatcgccca cggcctggcg
    13441 ccattagcca gccatccact ggggctggtg acgctggcat tgatctgctc tttcccgctg
    13501 ctgtcgccct ttctcggccc aggcgcggtt atcgctcagg ttattggcgt tctgatcggc
    13561 gttcagatag gtctgggcaa tatccccccg catctggcgc tgcccgccct gttcgcgatt
    13621 aacgcgcagg cggcctgcga ctttatcccg gtcggcctgt cactggcgga agcgaaacaa
    13681 gacaccgttc gcgtcggcgt accttctgtg ctggtcggac gcttcctgac cggcgcgccc
    13741 acggtactta tcgcctggtt tgtttccggc tttatctatc aataagaggt tcagacatga
    13801 gcgtgattta tcaaaccacc atcacccgca tcggccagag cgcgatggag gcgctcggcg
    13861 aaaagatgct gattacgttt cgggaaggcg cgccggcgga tatcgaagaa ttttgcttca
    13921 tccattgtca tggcgaactg accggcgcgc tgcagcctgg cgcgcggtgt gaactgggcc
    13981 aacattgcta tccggtcacg gcggtcggca gcgtagccga gcaaaacctg cgtgaactgg
    14041 ggcatatcac cttgcgcttt gatggtctgc gcgaagcgga atttcccggc accgtacacg
    14101 ttgcggggcc tgtaccggac gatatcgcgc cgggctgtat tttgacgttt gtcgcttaag
    14161 gagaaaaaac atgaatcaag ttgccgttgt cattggcgga ggccagaccc tgggggcatt
    14221 cctttgccgt gggcttgcag aagaaggata ccgcgtggcg gtcgttgata ttcaaagcga
    14281 taaagccgcg aatgtcgccc aggaaattaa cgccgatttt ggcgaaggta tggcctacgg
    14341 ttttggcgcc gacgccacca gcgagcagag cgtgctggcg ctgtcccgcg gcgtagacga
    14401 gattttcggg cgcgtcgatc tgctggttta cagcgcgggt atcgccaaag cggcgtttat
    14461 cagcgatttc cagttgggcg attttgaccg ctcgctacag gtgaatctgg tgggctattt
    14521 cctctgcgcc cgtgagtttt cccgcctgat gatccgcgac ggcattcagg ggcgcattat
    14581 tcagattaac tctaaatccg gcaaagtggg cagtaaacac aactccggct acagcgcggc
    14641 gaaattcggc ggcgtggggt taacccagtc tctggcgctg gacctggcgg aatacggcat
    14701 taccgtacac tcgctgatgc tcggcaacct gttgaaatcg ccgatgttcc agtcattgct
    14761 gccgcaatac gccactaaac tgtgcattaa gcccgacgag gtggaacagt attacattga
    14821 taaagtaccg ctcaaacgcg ggtgtgatta tcaggatgtg ctgaacatgc tgctatttta
    14881 tgccagcccg aaagcgtctt attgcaccgg gcagtcgatc aacgtaaccg gcggtcaagt
    14941 gatgttctga ccgtgaattg ccggatggcg ccgtaggccg gataagacgg ttacgccgcc
    15001 atcaggcaaa acaacaggag cacattatgg tttccactct gattaccgtc gccgttatcg
    15061 cctggtgtgc acaactggcg ctgggcggct ggcagatttc ccgctttaat cgggctttcg
    15121 ataaacttag ccaacaggga cgggtcggcg tcgggcgctc cggcgggcgt tttaagcccc
    15181 gggtggtggt tgccgtggcg ctggacgaac agcagcgggt gacggacact ttattgatga
    15241 aaggccttac ggtattcgcc agaccggtta aaattgccgc aatgcaagga aaacatttgc
    15301 atgaattaca gcctgatgtg atctttcccc atgattcgct cgcgcagaat gcactatcat
    15361 tggcgcttaa actgaaacat gggtaatttc gttgtgaatg cgaatagctt gcgaaattat
    15421 cattttgcaa cctataccct aaataattcg agttgcagga aggcggcgac gcagcgaatc
    15481 ccctggaacg tacatcaata cgtgaccggg gtgagcgagg aaagccaacg cacatgcagc
    15541 gtgaagtatt acgggtaaat acataagtca gggtaatcac gcctatgaaa cctcgtcagc
    15601 gtcaggccgc gattctggag cacctgcaaa aacagggaaa atgctcggtt gaagaactgg
    15661 cccagtactt tgacacgaca ggcaccacta tccgtaaaga tctggtcatt ctggaaaatg
    15721 ccggaaccgt catccgcacc tatggcggcg tggtgttgaa taaagaagag tccgatccgc
    15781 ctattgatca caaaacgctt atcaacaccc acaaaaaagc gctgatagcc gcagccgctg
    15841 tgaaatatat ccatgatggc gattccatta ttctggacgc cggaagtacc gtgttacaga
    15901 tggtgccgtt gctttcgcgt tttagcaaca tcacggtgat gaccaacagc ctccatattg
    15961 ttaacgcgct atcggaactg gacaacgaac aaactatcct gatgcccggc ggcaccttcc
    16021 gtaaaaaatc ggcgtcgttt cacggtcaac tggcggaaaa cgcctttgag caattcagct
    16081 ttgataaact tttcatggga actgacggta ttgacctgaa tgtcggtgtg accacgttca
    16141 atgaggttta caccgtcagt aacgcaatgt gcaatgcagc acgcgaggtg attctgatgg
    16201 cggactcctc aaaatttggt cgtaaaagcc ccaatgtggt gtgcagtctg gaaaccgtcg
    16261 acaaactgat cacggacgcg gggatcgatc cggcatttcg tcaggcgctg gaagcaaaag
    16321 ggattgaagt aatcataacc ggagaaagca atgagtgatg cactactaaa cgcgggccgt
    16381 cagaccttaa tgctggagct acaggaagcc agccgtctgc cggagcgtct gggcgatgat
    16441 tttgtccgcg ccgccaatat cattattcac tgtgaaggca aagtgatcgt ttccggtatt
    16501 ggtaaatcag gtcatattgg taaaaaaatc gccgcgacgc ttgccagtac cggtactccc
    16561 gctttttttg ttcatccggc ggaagcactg catggcgatc tggggatgat tgaaagccgc
    16621 gacgtgatgt tatttatctc ctattccggc ggcgcaaaag aactcgacct catcatcccg
    16681 cgtctggaag ataaatccgt cgcgctgctg gcgatgaccg gtaaacctca ctctccgctg
    16741 gggcgagcgg caaaagccgt tctggatatt tccgtcgagc gtgaagcctg tccgatgcat
    16801 ctggcgccga catccagtac cgtcaatacg ctgatgatgg gcgatgcgct ggcgatggcg
    16861 gtcatgcagg cgcgcggttt taacgaagaa gatttcgccc gttcgcatcc ggctggcgca
    16921 ctgggcgcgc gtttgctcaa taatgtgcat cacctgatgc gccagggcga tgcaataccg
    16981 caggtgatgc tcgccaccag cgtgatggat gccatgctgg aacttagccg taccgggctg
    17041 gggctggtgg cggtttgcga tgagcaacat gttgtgaaag gcgtctttac cgacggcgac
    17101 ctgcgtcgct ggctggtagg cggcggcgcg ctcaccacgc cagtaagcga agccatgacg
    17161 cccaacggta ttacgctcca ggcgcaaagc cgcgccattg acgccaaaga gctcctgatg
    17221 aaacgcaaaa ttaccgccgc gccagtggtc gatgaaaacg gcaaactcac cggcgccatt
    17281 aacctgcagg atttctacca ggcggggatt atctaatcct tcagtcccag acgcttcgcc
    17341 agccgatgca ggttggcgac gtcggtttcc agcgcccgcg cactggccgc ccagttgtga
    17401 ttattttgcg ccagcgcctg gcgaatcatc tctcgctgga agttctccgt cgattcgcgc
    17461 aaattgcggc aggccggcaa cgccagaaag ctttccgcag acggcgcggg taaaacgtcc
    17521 tctgacaagg caaaatgctg ctcctccagt accacctcat cccctgcccg ggtcgctctc
    17581 gccagtacaa ccgcacggtg aatggcatgt tccagctccc ggacgttgcc cggccagcca
    17641 tagttgagca aatggcggcg cgcgccggga ctcagtacca cgcgggacag ccccagccgc
    17701 agtcggcact gctcgcaaaa atagcccgcc agcaacacca catcatcgcc gcgctcgcgc
    17761 agcggcggca caaagagcgg gaaaacgctc aggcgatgga acaggtcggc gcgaaaacgc
    17821 cccgccagca cctcttcacg caggtcacgg ttggtcgccg ccaacacccg cacatccacg
    17881 cgcaggctac gatcgtcgcc gacgcgctga atatcgccat actgcaacac gcgaagtagc
    17941 ttggcctgta gcgccagcga cagttcgcca atctcatcca gaaacagcgt accgttatcc
    18001 gccatttcaa acttaccgct acgattactg atagccccgg taaaagcccc ttttacatga
    18061 ccaaacaact cgctctccgc cacgctttcc ggcagcgcgg cgcagttgag atagaccagc
    18121 ggattgaccg ctctggggga gccctggtga atagctttcg ccaccagctc tttaccggtc
    18181 cccgtttcac cgccgatcag cacgttaaga tcggagcccg ccacaatctc gatctctttt
    18241 ttcaactgcg tcatcgccgg cgacagaccg atcatgtgcg tctcttttat cggttcaaac
    18301 acgcctgacg accccggcag catgttctgg ctttccagtt gttcaattaa cagcgcatta
    18361 ctcaatgccc cggcggccag cgcggcgaca agccgtagtt cttcatcgct aaatacctcg
    18421 aactgctccg gcgtcatagc atcaagggtc agcgcaccga tgaggttctg tccggcaaac
    18481 agcggcagac caacacaggc gtggactttc aggctttcct gtccgggaat taacccgtca
    18541 tatggatcgg gtaaatcgct atcagccgga aaacgcacca cgtcccccgc gcgggcgatg
    18601 gcttccaggc gcggatgccc ttccagggta aaacgtctgc cgaggacgtc ctgcgccagg
    18661 ccatcaatcg ccagtggaat aaattgtcgt gattcataac gcagcagcgc cgaggcgtcg
    18721 cacgccagca cctgacgcag cgtagtaatc agccgctgaa aacgatcctg atgcccaatg
    18781 ccgcgttgta actcaatggc gatgcccgcc aatacctcca cggaaaaact catggttacc
    18841 tcattgtcat tttgacaatc tatagtgtca tattgacagc atcatttata gtctttttga
    18901 ctataccaaa aatacaaaat tattataatt tcatataaat caataagatg taaagttggc
    18961 acactacctg caataagcaa aacaactttt tgcaaacgtt gaatgaattg aggtggttat
    19021 gtctattctg gttaaaaata atattcattg ggttggccaa cgcgactggg aagtacgtga
    19081 ttttcacggc actgaataca aaacgctgcg tggcagcagc tataacagct atctcattcg
    19141 tgaagaaaag aatgtgctga tcgataccgt cgatcataag tttagccgtg agtttgtgca
    19201 aaatctgcgc agtgaaatcg acctcgcgga catcgactac atcatcatta accatgccga
    19261 agaagaccat gcaggcgcgc tgaccgaact gatggcgcag atcccggaca cgcctatcta
    19321 ctgtaccgcc aacgccattg actctatcaa cggccatcac catcacccgg aatggaattt
    19381 taaggtggtg aaaaccggcg atacgctgga tatcggcgac ggcaagcagt tgatcttcgt
    19441 ggaaacgccg atgctgcact ggccggacag catgatgacc tatatgaccg gcgacgcggt
    19501 gttattcagc aacgacgcct ttggtcagca ctactgcgac gagcacctgt tcaatgatga
    19561 agtggaccaa actgaactgt ttgaacaatg ccagcgctac tacgccaata tcctgacgcc
    19621 gttcagccgt ctggtaacgc caaaaattac cgaaatcctc ggcttcaacc tgccggtgga
    19681 tatgattgcc acctcacacg gcgtggtatg gcgcgacaac ccaacgcaaa tcgtggagct
    19741 gtatctgaaa tgggcggcag attatcagga agatcgtatc actattttct acgataccat
    19801 gtcgaacaat actcgcatga tggcggatgc catcgcacag ggtatcaatg aagtggaccc
    19861 caacgtggcg gtcaaaatct ttaacgtcgc ccgcagcgat aaaaatgaaa tattgaccaa
    19921 cgtcttccgt tcgaaaggcg tgctggtcgg cacttctacc atgaacaacg tgatgatgcc
    19981 gaaaatcgct ggtctggtgg aagagatgac cggcctgcgc tttcgcaaca aacgcgccag
    20041 cgccttcggt tctcatggct ggagcggcgg cgcggtggat cgactgtcca cgcgcttaca
    20101 ggatgccggt tttgaaatgt ccctgagtct gaaagcgaaa tggcgtccgg atctggatgc
    20161 gctggagttg tgccgtcagc atggtcgcga catcgcccgt cagtgggcgc ttgctccgct
    20221 gccggaaacc acacagaaaa ccgcgccagt cgaagaaacc acaacctgca ccgccgcaga
    20281 cctcggcccc aaaatgcaat gcagcgtatg ccagtggatt tacgaccctg cgctgggcga
    20341 gccgttgcag gatgtcgcgc cgggtacgcc gtggagcgac gtgccggata acttcctgtg
    20401 cccggaatgt tcattaggta aagacgtgtt cgacgtactg gcgacggagg caaaatgagt
    20461 cgggggatca tcattattgg gtcgggcttc gccgcccgcc agctcgtcaa aaatatccgt
    20521 aaacaagatg cgcatgtgcc gttaactctg attgcggcgg acagcatgga tgagtacaac
    20581 aagcccgatc tcagccacgt tatcagccag tcgcagcgcg ccgatgatct cacccgccag
    20641 ttagcggggg aatttgctga acagtttaat ctacgactgt tcccgcatac ctgggttact
    20701 gacattgatg ccgatgccca tgtggtgaaa agtcaggata agcagtggca gtacgacaag
    20761 ctggtactga cgaccggggc gacagccttt gtgccgccga ttgcaggacg tgagttaatg
    20821 cttactttga atagccagca ggagtaccgc gcctgtgaga caccactgcg cgacgcgcag
    20881 cgagtgctga ttgtcggcgg cggtctcatt ggcagtgaat tagcaatgga tttctgccgc
    20941 gccgggaaaa cggtaacgct gatggataac gccgccagcc ttctcgcctc actgatgcca
    21001 ccggaagtga gcagtcgctt acagcatcac ctgaccgata tgggggtgca tctgctgctg
    21061 aaatcgcagt tgcaaaaact ggagaaaacc gaagccggta tccgcgctac gctggtaagc
    21121 cagcatagta ttgaggtcga tgcggtgatt gccgccaccg gcttacgccc ggagaccgct
    21181 ctggcgcgcc gcgccggggt agccgtcaac cgcggcgtct gcgtggatag ctatctacag
    21241 accagtcacc cggatattta tgcgatcggc gattgcgcgg aaatcaatgg tcaggtgctg
    21301 cccttcctgc aaccgatcca gttaagcgcg atgtacctgg cgaaaaatct gctcggcggc
    21361 aacgcgccgc tgaagctacc ggcgatgctg gtcaaagtca aaacgccgga actgccgctg
    21421 catctggcgg gagaaactca gcgccgcgat ttaagctggc agattaccgc agaatctgac
    21481 ggtatgattg ccaaaggcat gagtggagaa ggccagctac gcgcctttgt ggtgagtgaa
    21541 gaccgcatga aagaggcctt tgcactgctg aaaacgttgt cggtataagc ctgtgatgcc
    21601 ggatagcgcc gcttcgcgtc ttatccggcc tacgagtgag catctgttta cacgccggat
    21661 aaggcgcagc cgccatccgg cgccctacac ttcccttaac gctcgcgctg cggcaatcac
    21721 gccctgtcca aacgacagtc cgccgtcgcc cgccggtaac cgctgcggaa ataacaattt
    21781 aaaatcagaa agataaaagg caagacgcgc gcgcagtaag cggttgtgta tcaccccgcc
    21841 gctgaagacc agagtggtta tcccccgcgc cgtagcctgt tggcgcatta gcgtggcaaa
    21901 cccgcacgcc agcgcatcat gaaaagccca ggcgcgttgc gcgggcgtgg cctgccagtt
    21961 caaccattgc cgccagaaaa cagcgacgtc cagttgagcg ccgttaagcg gcatcgttac
    22021 cggatactca acgttagcgc attgagaggc cagcgcctcc agcgcgcagg cggcctcgcc
    22081 ctcatagcta agcgatgctg gcgcgcagcg aagcgcggca gccaccgcgt caaacaaccg
    22141 cccgcaggaa gaggccaacg gggcattgac gccgcgctca atggcgcgcg ccaggacact
    22201 ccagttttgc tgttgcagcc ccgctgtctc cgggtaattc tgccagtccg gcacaaagcg
    22261 caggcactgc gctaacagat tacgccacgg ctgtttggca gccagatcgc ctcccggcag
    22321 cgccacggcg ggtaaaccgc ctaaatgttc gcattcgcga taattgaccc gcaaacattc
    22381 tccgccccat agcgcgccat tctcacccat gccgataccg tctaccgtca gggcaatcac
    22441 ctctccgccg tccagcggcc aaccatgctc ggccaggcaa gccgccgcat gggcatgatg
    22501 gtgtaacacc gtctctgtcg gcagacgcat ctcactggcc cactgactgg aaacatagcc
    22561 cggatgcgca tcacagacga tacgctctgg cgtaaaatcg tagattgact ggatcaaacg
    22621 caatgcctcg cgccactgcg cctggatacc gtcatcgctg agatcgccta aatgttggct
    22681 gacaaccgcc tgttcgccgc gtaccagaca gaacgtgttt ttcagatccg cgcccagaca
    22741 aagtatcggc ggcacatcgc gaaatccggg cggcaacgca atcgcgtccg gcacgtatcc
    22801 ccgcgaacga cgcagcattt cgccgctgtc gcgcacgaca gagtcgtcca tgcgctgtac
    22861 aatgtcgcga ttgtgcaaca gaaaaccatc ggcaatatcg tgtaaatcgt ccagcgcctg
    22921 ttcgttggtg atggcgggcg gtttgccgct caggttgccg gatgtcatca ccagcgggta
    22981 attgagtgcc tgcaacaaga gatgttgcaa tgggttggct ggcagcatca cgcccacttc
    23041 cgtaagtcct ggcgcgatgc cctcactcag cgaaggtaca tactgcttat ccaccagtac
    23101 aatcggggcc gctggcgtgg tcagcagcga acgcgccgcg gtcggcagcg tttgcgccgt
    23161 gggcaacatc accgccaatg gtttcgccgg acgatgttta cgcgcccgca gcatcgccac
    23221 tgcgttatcg ttgcgcgcgt cgcaggccag atgaaaacca cccagccctt taacggcaat
    23281 aatgcctccg gcgttcagtt gggcgaccgc cgcctgcaaa gccgcctctt tttccgctcg
    23341 ttcatgttgg ctccgccact caagatgcgg cccgcatgac ggacaggcaa cgggctgggc
    23401 atgaaaacgg cgatcgtacg gatcgcggta ttcgctgtcg cattccggac acaagggaaa
    23461 cgccgccatc accgtaaatg gccggtcata gggcatagcg cgaataatgg tgaagcgtgg
    23521 tccgcagtgg gtgcaattga tgaaaggata acggtagcgc cgctcgcctg gggtattcat
    23581 ctcggcaaga catgccgggc aggtcgccgc atccggcacg atttgcgtgt tcatcgaacc
    23641 gcctgcgctc tgacgaatgg tgaaatccgt cggtgcgcgc tcccatacca acgacgcgtg
    23701 ttcaacgctg tcaatgcgcg ccagcggcgg gcaatcctga tagagcgcgg caataaattg
    23761 cgacggatct tccagcagcc gaacgacgac gccgtcgccg tcattacaca cgtcgccgtg
    23821 taattgcaac tgctgcgcca gctgccagac aaaaggacga aaaccgacgc cctgtacttt
    23881 gccccgaatg cgtagctgta cgccggaagg tgtgtctatc gccatcttat tttcccgcca
    23941 tcatcgaacc cggatgcctg atggcgcgac gcttatcagg cctacaaccg cacggaccgt
    24001 agaccggata aggcattgat gccgccatcc ggcaatgctt tgtggcgtat tctacgcgca
    24061 atcgcagaaa tcagaaaagc agcgatgccg ttgaatccag cgccgcacga cggcgttttt
    24121 ccgcgctcag ctgttcaagc ttattgcggt ccacgcagat gagggcgtgc gttgggcaag
    24181 cggccataca ggccggaccg gcttcacggt ggtgacacag atcgcacttg ttggcttcgg
    24241 ctttttcggc acgcacgttt agccccgcgc cgctattgcg aaccaccgga cgaaccacca
    24301 cttccatggc gccgtaagga catgccacta cgcaagtttt acagccaatg cagcgttcct
    24361 gcatcacatg aacaaagcct ttgtcacggc tgatggcacc attcgggcaa acgttggcgc
    24421 acggcgcatc ttcacactgg cgacacagcg ttgccgtgga aacgttcacg cctttgataa
    24481 catggatacg aggtaaaaag gtttcagggg tcagcgatgc gcaatcctga ttttcctgat
    24541 gggatacgac gcaagccact tcacaggtac ggcaaccaat gcacttactc gcgtctgcaa
    24601 tgatgaaacg gttcatcaaa ttctccagca ataacagatg atgtgccgat atatacacga
    24661 atcgtgccaa tttttatttc attgttattt aagaatattc tttctatttt cgtgagcatt
    24721 tacgtgtcat cgtcacaagt gtcgatgaca cgtaatgtcg ccagtggtgg tcaagatttg
    24781 cagtgatagc cagccaactc tgcacagaaa ctggcatcaa tcctgattaa cgcctggcaa
    24841 tacgttaccg cgtattaaac agcgctgcgt aagggaaaga tcgtccgttt gcggattcct
    24901 tccggcaata ggtttgataa ttaatttacg gccaggatag tgattaaagc gggtcagcgc
    24961 cggataactc aaccggccaa accagccgtg tacgcgctgc cagcgggcgt ccttcacctg
    25021 atataaattg gttatccagt agcctgagtc aaactgcata tccaacagtt gcgtgcgacc
    25081 attgccctgt aaatcaagca aatcatcgac gccagtatcg gtggcggtat aaaaccccca
    25141 cggttcaaag acgcaggggc ggccattctt gagaaaggtg aaaatgatgt attgcgcgct
    25201 cggcgccagg cccaacccag gattgcccaa ccagataacc aagtcctgaa tgccgttacg
    25261 atcgaggtca gcgcgataaa attgcgcatt acccgccaaa ttaatcagcc ttcccaccgg
    25321 gacaacccac gaattaccgg ctctgtcttt tccgctaatc cgccattcgt tatctttttt
    25381 cggctccggc agtagcgtca cgctactgac tccgacctgg cgaaaatgcc aggtctggtc
    25441 gggcgataca gaataaggca ggatcaaaag cggcttcagc gcacgctttt gcgcatattc
    25501 accgtcgctc atcggcaggt aaccgacaac accggtagcc agtgcgcgtg cggcgaggca
    25561 gagaaatagc agtccgctcc atacgataat cttcacgttc ttcttaccgc ctatgccggg
    25621 taacacaaat ccatccagaa tgagtacgca ttttacgcct ccggcgcgtc cagcgcggca
    25681 aatccgccgt ttccctgcca gccttccagg cgctgataga cgatgtttac cgcgtcctta
    25741 atcggttgag tcatcggata ataaaacccg acgatatccg gctggatacc aacaaaaatc
    25801 acctcgccga catcctcttt cagcagatcg ataaggtagt tcagcggcat attgtgggtg
    25861 gtcatcataa acatttcggc gatatcatcc ggatcgatga tgcggatctc gcccggatta
    25921 agtcccatat cggtggcgtc gacaatcaac agacgctgcg ggcgcagttc gcgaatcgcc
    25981 acaatgtcgt tttccggcgc gctgccgcca tcgatgacaa cccagttgcc cttcggctgc
    26041 gccgcgcaca tttccgccag taatgggcct gcgccgtcgt cgcccatcat gctgttgccg
    26101 acacagagta aaacgtcagt cacgaagcct cctcaccatc aggtagatgg cgctttcctg
    26161 atgaatgtca tgcagcatac tgagcatcag tttgctccat tcttgctgct gcggggtctg
    26221 cgcggcgcgc gcctcatcaa acgcgcgcgc cagcatttgc acatggttga aatcgatgac
    26281 gatctcgcca tacttcggca cgccttccat tttacgccgg gcatcgctac cggcttccag
    26341 ggtggcgatc cacgccagat actcatccca tgggcaggtg agcgcggcct ccaggcaatc
    26401 gataaccccc aggtggtgac caatcgccag gctgtaatag acaacctgct gcgcctcggc
    26461 gggcgtcgca tcgttctcat caataaactt acggctcagt tgactgaaca ccacctgttc
    26521 gctcatcgga tacgcgcctc ttcaacaaca tgattgagat ggatgacaat ttcggttaaa
    26581 cgcggatcgt tttccgcttc cagccaacgc gccacttgct gctcgccctg ccccaactgt
    26641 gtcaggtaat catcggcgat ctgacgacca tagcgataac ccgccagccg gcacgccgcg
    26701 cgatccacct tcacgcgcag cggctgcacc atatccggat gcaggatctc tgcgggctga
    26761 tcgtccagct cacccggcgc gcgggcgtgg attttctgct ccagcaggcc aagcgccatt
    26821 gcaaagccat acagcgtggc ggcaggcgtt ggcgggcagc ctggaatgta cacatccacc
    26881 gggacgattt tgtcggtacc gccccagacg cagtacagat catggaagat gccgccgctg
    26941 ttgccgcagg cgccgtaaga gatacaaatt ttcgggtccg gcgccgactg ccaggcgcgc
    27001 agcgccggag agcgcatggc gcgggtcacc gcgccggtaa acagcagaat atcggcatga
    27061 cgcggcgacg gtactacttt gatgccgaaa cgctcggcat caaacagcgg cgaaagcgtc
    27121 gcaaagattt cgatttcaca gccgttacag ccgccgcagt ccacgcggta aacgtatgcc
    27181 gaacgcttaa tatttttcag tagagacgcc ttcatgctgg cgatggattc atccaccgtc
    27241 atcggtaccg gaatgccgtt ggcgtcacgc gggcctaata aattgctcat tagctgacct
    27301 ctttcatatg gcgagtcagt tcaatacggt cggacggcac caggcatttc tgacgcttac
    27361 agtccgggca ggtctcaaag ctttcgcggt ggttttctgc tcggctgtcg ccgttgtgcg
    27421 caagcagcgc aatggcgtag tcgatctctt tctgtaccgc gaaaggacga ttgcacacgc
    27481 ggcagttgca cagcgcgaag cgggactgtt gcaggaagtc ttctttcttc cacactgcca
    27541 gttcgtactc ttgcgacagt ttgatcgccg ccgtcgggca cacctcttcg cagcgaccgc
    27601 agaagatgca gcggccaaga ttgaactgcc acgccagctc attggtcgca agatcggttt
    27661 ccaccgtcag cgcgttcgac gggcaggcat taacgcaggc ggcgcagccg atgcactgct
    27721 gcggattatg ttccggcttg ccgcggaagt ttttatcaac cgcaatcggc tccagcggat
    27781 aagacgaggt cgccgtgccg gttttgataa cttttttgat aaaggtaaac atggcgattc
    27841 cttatttcag cggcgagttt ttacgctcaa tgctgtagcg ctcaagttct ttgtacggca
    27901 cgactttgct cttcttctta cgtacatcga ccacggtcat ccggtcggta caggagtagc
    27961 aaggatcgag gctaccgatg atcagcggcg cgtcggagac ggtgttgcca cgcagcatat
    28021 aacgcagggt cggccagttg gcgtaggttg ccgcacggca gcgccagcgg taaagcttct
    28081 ggttgtcgcc ggtcatgctc cagtggatat cgtcaccacg cggcgcttca gcgaagccga
    28141 gcgcaaaacg gtgcggaata taggtaaagc cttccaccat cagcgggccg cccggtagat
    28201 tatccagacc gaaatcgatc atattcagcg aggtgtagac ttcgttgata cggactttca
    28261 gacgagaaat cacgtcgcag ccctgctcgc tatgtacttc catcggcagc agaccgtagc
    28321 cgacaaacgg gtggtcggcg cgggtgtcgc gggcgtgacc gctggcgcgc accatcgggc
    28381 cgacattact gaagtcgcgg gcaatttccg ggtccagacg gccgataccc acggtacgct
    28441 gttccatatt cggcgtgctc agcagcatgt ccaccagctc ctgcacgtca cgacgcatct
    28501 gctgcgccag ttgacgggtc tggatcatgt cctctttgag cagatcgcgg cgaatcccgc
    28561 cgatcaggtt cagaccgtaa gttttgcgcg ccccggtcag tatttccgcc atcttcatgg
    28621 aggtttcacg cacgcggaag aactgcataa agccggagtc aaagccggta aagtggcagg
    28681 cgaggcctag gttcagcagg tgcgagtgca gacgctccac ttccagcaga atggcgcgga
    28741 tcatctgcgc acgctccggc acctgaatgc ccatcgcgtt ttccacggaa gtggtgtagg
    28801 cagtgctgtg cgcgaaaccg cagattccac acacgcgatc cgacaggaag gtgacttcgt
    28861 tataacccat gcgggtttcc gccagttttt ccataccacg gtggacgtag aacaggcggt
    28921 agtcggcatc gataatgttt tcgccatcga cgaacagacg gaagtggccc ggttcatcgg
    28981 aagtgacatg cagcgggcca atcggcacca cgttattttt cttgtcaccc agctcgttaa
    29041 tgaactcgta ggtttccgca tcggtggtcg gcgccgggcg ctgacgataa tccatgctgt
    29101 ctttacgcag cggatagagt tcatccggcc agtcgtccgg cagcaccaga cggcgctcgt
    29161 ccggcagacc gaccgggatt aaaccgtaca tgtcgcgtac ttcgcgctca ccccacacgg
    29221 cagccggcac gcgcggcgta acggatggga attccagctt attggcatcc acttcaacac
    29281 ggacggtaat ccagcacttg gtgccctgct ccatcgacag cacgtaataa acggcatagt
    29341 ggccgcacaa ctggcgttcg tcattaccga acagcaccga cagccaccca ccctgctggt
    29401 agtaaagaaa ctccaccact tccggcagat agttcacttt taccgtaata gtcagctgat
    29461 ctttggtctg ccaggcttcg tccatcacga cgcccggaaa cgcctggtgc agcgccgcaa
    29521 ggtattgttg acctaatttt tcttcaaaca tgctcaaact ctcttaaatc acgccgccag
    29581 caaggagacg aaggctaaaa acgcaaaccc aaaaccggcc caggtcacgc gtgaagtggc
    29641 gcaaaaacgc agtcgcgcca tgctgttttc aaacagggcg atcaccagta cgccgacaat
    29701 cagcttgacg acggcaatca ccagcgccag taacagtccg cctgcgctga aggtttccat
    29761 ctgtccccac ggcaaaaaca cgccgacgaa catttgcagc accaccagtt gtttcaggct
    29821 gatgccccat ttcagcaccg caaagccgct accgctgtat tcggtcaacg gcccttcctg
    29881 caactcctgc tccgcttccg ccaggtcgaa cggcagcttg cccatttcga taaaggtggc
    29941 aaaggcgcag gcgcacagcg ccagaatcag cggaatactg cgcgcgacag gccagtgata
    30001 aatggtatcg gcgatattgc tgatatgagt tgaacccgcc acctgcgcgg ctacccacag
    30061 acccagcagc agaatcggct ccaccagcac gccgagcatc gcttcacggc tggcgccgat
    30121 cgcagtgaac ggactgccgg tatccaggcc tgcaatagag aagaagaagc gcgcaatcgc
    30181 gaacagataa atcagggtga ttaaatcacc cagttgcggc aacggagatc caacggtgac
    30241 gaccggcagc gcggtggcga tagtcagcat cacgccgacc atcacaaacg gcgtcaggcg
    30301 aaaaacccag ccggaatcag cgggcgcaat actctgacga ccgagcagtt tgataatgtc
    30361 gcggtactcc tgcaacacgc ccggcccacg gcgattgtgt agacgggcgc gcgccacgcg
    30421 agtaataccg gacagcaatg gcgcaacggc aaatagcacc agcgcctgaa ttaacggata
    30481 aaacacactc attttcaggc tcctcgtgaa accacaatca ccaccagcac cgccagctca
    30541 atcagcgcca gacgacggaa cagccccgcg gccgccgcgt tctgccagcc cggcaccagc
    30601 gataccgggt tcagccattt acgcagtttg agtaccgggg caaaggcctc tttcaccggc
    30661 atggcgaaac cgtgcgcggt aatcaccatc gactgctcat ggtcgtagcc gcacacccag
    30721 gccgcgccgc gagaacgcga cggcagacgg ttgcctttga acatcgccat aatgatgaat
    30781 ggcagtagcg gacaggcgac caacagcagc gtgatcatcg gctgcgatac ggtggtgtgc
    30841 gcggtttcca gcggcaacgg taccgcagtg gaaatcatcg gcagcagcca cggcgcggca
    30901 accccgccca gtacgcagca aaccgccaat gccaccacgc tgacgcccat caggatcggc
    30961 gcgcagctgg cattttcagc ttccttcgtg cgcggcgcgc caaggaacgt cacgccgtaa
    31021 actttcgcca tacacatcac cgccagcgcg ccggtaatcg ccaggccaac cgccagcagc
    31081 ggtcctaaca gacgaccaac aaacgcgccg ctgttgccca gtttgaagaa ggactggtaa
    31141 atcacccact cgccggcaaa gccgttcagc ggcggcagcg ccgccatcgc catcagaccg
    31201 accagcatgg cgatagaaat aaccggcatc cgtttaccaa taccgcccag tttttcgatg
    31261 tcgcgatgac cggtacggaa ccagatgctg cccgcgccca gtaacagcac gcttttgaac
    31321 aggctatggt tcagcagatg atagagcccg ccggtcagac ccagcgcgat cagtaccggc
    31381 tgattgagag caatcccggt aacgcctgcg cccagaccga gcaaaatgat gccgatattt
    31441 tccagcgtgt gataggccag caggcgctga atgttatgct ccatcagcgc gtacagaccg
    31501 ccgacaaagg cggtgatcat cccaagcacc aacagcgcca cgccccacca cagtggcgca
    31561 ttgccgccaa gcagagatag cgagagaatg cccagcagcc cgattttcat caccacggtc
    31621 gagaacagcg cggcggcggg agcgctggcg ttggcgtgcg cctgcggcac ccaaccgtgt
    31681 agcgggataa tcccggccag cagaccaaaa ccgataacgc cgagcagcca gatatcggag
    31741 cccagcggca gttgctgagc gcgttgatcc agcagcccca gatccagcgt gccgtagcgc
    31801 tgccacacca gccagcaggc gattgccagc agcagcgtac cgagacggcc cagcgcaaac
    31861 cacagtttgc cctctttgct accgccggta aggaacacgg cgcagagcgc catgatttca
    31921 gccatcacca ccatcgtccc cagattactg gcgaccacag cgcagacggc tgccgccatc
    31981 agcaggttga tcaacagtcc gttggctttt acctgtggat ggcgatgcca gtcgatattg
    32041 aacaggctga cgaacagacc gcacagcccc agcgtaatca gccagatagc attcagcggc
    32101 gtaatttgca gcatgtgacc ggtaaacggc atcacgccgc taaccgtaac ggcgctggtc
    32161 agcgcggtga accccgcgcc tgccgtacac aggctgccga ccgcgccgcc gataccggca
    32221 atccagccgc tcagcgcttt atgaaacgaa aacagaaacg ccagaacggc ggcggcggca
    32281 aaccacgcga cgccgctagt aatcagtgaa agtgaactca ttatgcatcc ccactctgag
    32341 cctgctgaaa caaggtgaga tcgccaaaat cggtattaaa cgtcagctca cgtttacgtt
    32401 tgctggcgcg ggcgatatcc gtgttctcca ccaggtgtag cgctttagtc gggcacatcc
    32461 gcacacaggc cgggccttgc tcgtcaaagc tgcacaggtc gcatttcacc gcgatagcgc
    32521 gcacgcccgg cacccagtcg agcaacgtac tgacgcgcgc aggcgctggc ggcgcgggcg
    32581 gcgctttcgg cgtattggcg ttcgccggaa tatgcagcgg acggctgccg gaaaactcaa
    32641 tagcgccaaa cggacaggca ataccgcaca gtttgcagct cacgcacagg ctttcattaa
    32701 gctggacagc gccgtcaacg cgattaatcg cgttaaccgg gcataccgtg gcgcatggcg
    32761 catcttcaca gtggtgacag agctgcggcg cagattcttt ttcattcagc atcactttca
    32821 ggcgcggcat tgactgcagg ccatgctggc gatgcgtctc tgaacaggcg gcctcacagg
    32881 tgtggcagcc gatacagaga gtggagtcaa caattacaaa acgattcacc aggcattcct
    32941 caggtgattg tcatttttga cgaaaacatg ccgttgaaat gtcattttcg acacttatcg
    33001 acacgcccat ccccaaaaca ttcatgacat ggcgcaacgc cacatcgcga atcaaagcgg
    33061 gcaacgcctc aggcttatac agccgggctg tgtcccttta ccaattggcg caaattaacc
    33121 ggcgagttgg tttctacagc ggtatagagg ctgtcgtaaa cgctggcgat tttttccaga
    33181 tagtgctcca gcacctgctc gcgatcgcgg ttgttaaccc gttcgtcaac cttgccgtcg
    33241 atatcgagct gcgcctgtgc aatcaattgc ttatcttcgc catctttggt ttcaacgtag
    33301 tactcaatgg tgtggctgtt aaaaccatcc gccaacgcaa cgtaaatacg aaagtgctca
    33361 aacaggacaa agcaaagatc cctttccggc gcgcagctca ttgcgtgatg caggcgcgct
    33421 ttcgagaggg tgatcccctg aaccagcgag ttgcagtaaa tatgccactg gtcctgtagg
    33481 cgacgatgcc gttgcgcgat gtaatcggcc ttttcgctta tttcccaaat agtcatgtca
    33541 ggttacccgt ttaacagaga tgcctgcgtt aagcattttc catgccaatt tttaacttat
    33601 tgtttttaat ggaagacgcg cacagttact gccgtttcga cgcggtgacg acatgtcatt
    33661 tcgtcatcgt cgacattaac ctgccagggg atacaaatat tggcataaat attgctttac
    33721 aggggcaacc actacgggag gcgatatgca cgaaatcacc ctctgccaac gggcactgga
    33781 attgattgaa caacaggctt cagcatacgg tgcaaaacgt gtgacagccg tctggatcaa
    33841 aattggcgca ttttcttgcg tggaaaccag cgctctttcc ttttgttttg atctggtatg
    33901 ccgcggcacg atagcagaag gttgtaaact gcacctcgaa gaacaggaag ccgaatgctg
    33961 gtgtgagcat tgtcaacaat atgtcacgtt gttaacccac cgtgtacgtc gttgtccgca
    34021 atgtcatagc gatacgctgc gaattgtggc cgatgacggc ttacaaattc ggcgcataga
    34081 gattgatgaa actgaagatt aatgccggat aagacgctcg cgtcgccatc cggcagaaag
    34141 cctgtaacaa gaagaagatc aggagtaagc gatgtgtacg acttgcggtt gcgctgaagg
    34201 caacctttat atagaaggcg atgaacataa tccgcactca gcgtttcgta gcgcgccctt
    34261 tgccccagcg gctcgcccgg cgctgaatat taccggcatt aaaacgcctg actttacccc
    34321 aagtcagacc gcagaaggcg atctgcatta cggccacggc gaagccggaa cccacgcgcc
    34381 tggtatgagt cagcggcgga tgctggaggt tgaaatcgac gtgctggaca aaaataatcg
    34441 tctggctgag cgcaaccgcg cccgtttcgc cgcccgccag caactggtgc tcaacctggt
    34501 gtccagcccc gggtccggta aaaccactct gctgaccgaa acgctgatga aattgaaaga
    34561 ccgtgtaccg tgcgcggtga ttgaaggcga ccagcagaca gtgaacgacg ccgcccgcat
    34621 ccgcgctacc ggcacgcccg ccattcaggt caacaccggt aaaggctgcc atcttgacgc
    34681 gcaaatgatc gccgacgccg cgccgcgcct gccgctggat gaccacggta ttctgtttat
    34741 cgaaaacgtc ggaaatcttg tctgcccggc cagcttcgat ctgggcgaaa agcataaagt
    34801 cgcagtgctt tccgtgaccg aaggtgaaga taagccgctg aagtatcccc atatgtttgc
    34861 cgcggcgtcg ctcatgctgc tcaataaagt cgatctgctg ccctacctca attttgacgt
    34921 tgagaagtgc atcgccagcg cgcgtgaagt gaacccggag attgaaatta tcctgatttc
    34981 cgccaccagc ggcgaaggca tggatcagtg gctggcctgg ctggaggcgc agcgatgtgc
    35041 ataggcgttc cgggtcaaat ccgcgccatt gacggcaatc aggcaaaagt tgacgtctgc
    35101 ggcattcagc gcgacgtcga tctcacatta gtcggcagtt gtgatgaaaa cggtcagccg
    35161 cgtctgggtc agtgggtgct ggttcatgtc ggattcgcca tgagcgtcat taacgaagcg
    35221 gaagcgcgcg acacgctcga cgcgctacaa aatatgtttg atgttgagcc ggacgtcggc
    35281 gcactgctgt atggtgagga gagataatgc gttttgttga cgagtaccgt gcgccggaac
    35341 aggtaatgca gctcattgaa cacctgcgtg aacgcgccgc ccttcttcct tacactgctg
    35401 aacgaccgct gcgcattatg gaagtctgcg ggggtcatac ccacgcgatt tttaaatttg
    35461 gtctcgatca gttactgccc gaaaacgtgg agtttattca cggccccggt tgtccggtct
    35521 gcgtgctgcc aatgggacgc atcgacagtt gcgtggaaat cgccagccat ccggaggtga
    35581 ttttctgcac ctttggcgat gccatgcgcg tgccggggaa acagggttct ctgttgcagg
    35641 ctaaagcgcg cggcgcggat gtgcgtattg tttattctcc gatggacgcg ctgaagctgg
    35701 cgcaggataa cccgacccgc aaagtggtat ttttcgggct gggctttgaa accaccatgc
    35761 cgaccaccgc catcacgcta cagcaggcaa aacagcgtga cgtgcgaaac ttctactttt
    35821 tctgccagca cattacactg atcccgacgc tgcgtagcct actggagcag ccggacaacg
    35881 gcattgacgc ctttcttgcg ccaggccacg tcagcatggt catcggcacc gaggcgtacc
    35941 agtttatcgc cgccgatttt catcgcccgc tggtggtggc tggattcgaa ccgcttgatc
    36001 tactgcaagg cgtggtcatg ctggttgagc agaaaatagc ggccctaagc caggttgaaa
    36061 accaataccg tcgcgtggtg ccggatgccg gaaacatgct ggcgcagcag gccatcgccg
    36121 atgtgttctg cgttaatggc gacagcgagt ggcgcggcct gggcgtgatt gaatcctccg
    36181 gcgtccacct gacgccggag tatcagcgct ttgacgccga agcgcatttc cgcccagcgc
    36241 cacagcaggt ctatgacgat ccgcgcgccc gctgcggcga agtgctgacc ggcagatgca
    36301 agccgcatca gtgcccgcta tttggtaaaa catgtaatcc agagaccgcg ttcggcgcgc
    36361 tgatggtctc ttccgaaggc gcatgcgccg cctggtatca gtatcgtcag caggagtgtg
    36421 aagtttgaac aatatacaac tcgcccacgg cagcggcggc caggctatgc aacagttgat
    36481 taatagcctg tttatggagg cctttgccaa cccgtggctg gcggaacaag aagatcaggc
    36541 gcgtctggag ctggcgcaac tgacggcgga gggcgaccgt ctggcgtttt ctaccgatag
    36601 ctatgtgatc gatccgctct ttttccccgg cggcaatatc ggcaaactgg cgatttgcgg
    36661 tacggcgaac gacgttgcgg tgagcggcgc gatcccccgc tatctctcct gcggctttat
    36721 ccttgaagaa gggctgccga tggagacgtt aaaaagcgtg gtcaatagca tggcggcgac
    36781 cgcacgggaa gcgggtatcg ccattgtaac cggcgacacc aaagttgtgc agcgcggcgc
    36841 ggcggataaa ttgtttatca acactgccgg catgggggcg attcccgccg atattcactg
    36901 gggcgcgcaa acgctgagcg ttggcgatgt gctgttagtc agcggtacgc ttggcgatca
    36961 cggcgccact atcctcaacc tgcgtgagca actgggactg gatggcgagc tggcgagcga
    37021 ctgcgcagta ttaacgccgc ttattcagac gttgcgtcat attgacggag tgaaggcatt
    37081 gcgtgacgcc acgcgcggcg gcgtgaatgc ggtcgcccat gagtttgcgg cgtcctgcgg
    37141 ttacggtatt gaattgtccg aatccgcact gccgctcaaa cctgccgtgc gcggcgtctg
    37201 cgagctgttg gggctggatg ccctgaactt tgccaacgaa ggaaaactgg tgattgccgt
    37261 tgaacggcag gccgcagatc gggcgttggc ggcattacgc gcgcatccgc tgggacgtga
    37321 tgcggcgctg attggcgaag tcgtggaacg caaaggcgtt cgcttagccg gactctatgg
    37381 cgtgaagcga acccttgatt tgccacacgc cgaaccatta cctcgtatat gctagcagcc
    37441 tgttggcagc atactgtagg ccggataaga cgcatttgcg gcgagatccg gcattaacgc
    37501 tgcattaacg cctgatggcg ctttgcttat caggcctacg gagtgtgtga ccagcgagtt
    37561 tgcggtcagc catccggcaa taacttacga cttataccta taattcattt accgttttcg
    37621 caccgttttg cggtattttc ctggaaaagc aacatgtcgt atacacccat gagcgatctt
    37681 ggacagcaag gcttgttcga tatcactcgt accttattgc agcagcccga tttggcgtcg
    37741 ctcagtgaag cgctttcgca actggtaaag cgttcagcgc tcgccgacag cgccggcatt
    37801 gtgctatggc aggcgcagtc gcaacgcgca caatattatg cgacgcgaga aaatggccgt
    37861 cctgttgaat atgaagatga aaccgtactg gcgcacggcc cggtacgtcg catcctttct
    37921 cgccccgatg cattgcactg taatttccat gagtttaccg aaacctggcc gcagcttgcc
    37981 gcgagcggcc tctaccctga atttggtcat tactgtctgc ttcctttagc cgcggagggc
    38041 cgtattttcg gcggctgcga attcatccgt caggaagatc gcccctggag tgaaaaggaa
    38101 tatgaccgtc tgcatacgtt tacccaaatt gtcggcgtgg tcgccgagca aattcaaaac
    38161 cgggtaaaca ataatgtcga ttatgatctg ttgtgccgcg aacgcgataa cttccgtatt
    38221 ctggttgcga ttaccaacgc cgtcctgtcg cgtctggata ttaatgagct ggtaagcgaa
    38281 gtcgcaaaag agatccacca ctatttcaat atcgacgcga tcagcatcgt gttgcgcagc
    38341 catcgcaaaa ataagctgaa tatctactcc actcactacc ttgatgagca tcatccggcg
    38401 cacgaacaga gcgaagtcga cgaagccggc acgctcacgg agcgcgtctt taaaagtaaa
    38461 gagatgctgc ttatcaacct caacgaacgc gatccgcttg ccccctacga acgaatgctg
    38521 ttcgatacct ggggcaatca gatccagacg ctttgcctgc tgccgttgat gtccggcaag
    38581 acgatgcttg gcgtgctcaa actggcccag tgcgaagaaa aagtgtttac caccgccaac
    38641 ctcaagctgc tacgtcagat tgccgaacgg gtagccattg ccgtggataa tgcgctggcc
    38701 tatcaggaaa tccaccgtct gaaggaacgc ctggtcgacg aaaatctggc gctcacggag
    38761 cagcttaata acgtcgacag cgagtttggc gagatcatcg ggcgcagcga agcgatgtac
    38821 aacgtgctaa agcaggttga gatggtggcg cagagcgaca gtaccgtgct gattctgggc
    38881 gaaacgggaa ccagtaaaga gttgattgcc cgcgccattc acaacctgag cggacgtagc
    38941 gggcgcagaa tggtaaagat gaactgcgcc gcgatgccgg cggggctgct ggaaagcgat
    39001 ctgtttggtc atgagcgcgg cgcgtttacc ggcgccagcg cgcagcggat tggccgtttc
    39061 gagctggcgg ataaaagctc gctgtttctg gatgaagtgg gcgacatgcc gctggagcta
    39121 cagcctaagc tgctgcgcgt ccttcaggag caagagtttg aacgtctcgg cagcaataaa
    39181 ctgatccaga ccgacgtgcg gctgatcgcc gcgactaacc gcgatctgaa aaaaatggtc
    39241 gccgatcgcg aattccataa cgatctctac tatcggctga atgtttttcc gattcagctt
    39301 cctccgttac gcgaacgtcc ggaagatatt ccactgctgg tcaaagcgtt taccttcaaa
    39361 atcgcccgcc gaatggggcg taatatcgac agcattcccg ccgaaacgct gcgcacgctc
    39421 agcggtatgg aatggccggg gaacgttcgc gaactggaga atgtcgtcga gcgcgccgtg
    39481 ctgctgacgc gcggcaatgt gctacaactg tcgctgccgg atatgactgc cgtaacgccc
    39541 gatacctcgc ctgttgcgac tgaaagcgcc aaagaaggcg aagatgaata tcagcttatt
    39601 atacgcgtgc tgaaagagac caatggcgta gtggctggac caaaaggcgc ggcgcagcgt
    39661 ctggggctta aacgaacccc cctgctgtcg cgtatgaagc gattgggtat tgataaagac
    39721 gcgttagcgt aacgggttgc cggatctgat ccggcctgga gatgatgcgc gccgtaggcc
    39781 tggcgcttcc ccttcacttc ttgcgctgat atttttccgg caattctgga acggggcgct
    39841 tatcgtcgat aaggtgccgc acggtcagga caggatgccg ccaaagcatt cgcggacctg
    39901 cccaacgcat aatctgcttc atctcctcgc gtttagccgg ctgatagcag tgcaccgggc
    39961 actgcttaca ggcgggtttt tcctcgccaa atacgcattt atcaagacgt ttttgcgcgt
    40021 aggcgaacag cgcgtcgtaa tgcccctgca ccgctgacgc ctgtggacac tggctttcat
    40081 acagcgcgat catttttttg atcgtcagtt tttcacgagc gatacgttta ccaggcatcg
    40141 tgctctctcc gaacattaag atgcatttat tttacacctt atccctcttt agcactatca
    40201 ctgcatatcg tcgccattac gcaaataaga attattttca tttattcatg ccttgtgcta
    40261 tataacatag caaaggctat attcgatgat taattaacca cattgttgcg agggatacta
    40321 tgacgaatct acatcgtcta aaaacactcc tgattgccgg tattgtcgcg atactcgcgc
    40381 tatcgccagc ctatgcaaaa gagaaattta aagtcatcac cacgtttacc gttattgccg
    40441 acatggcgaa aaacgtggcg ggcgacgcag cggaagtcag ctcgattacc aagcccggcg
    40501 ctgaaatcca tgagtatcag ccaacgcccg gcgatattaa acgagcgcag ggggcacagc
    40561 ttatcctcgc gaatggtctg aacctggagc gatggttcgc ccgcttttat cagcaccttt
    40621 ccggtgtacc ggaagtcgtc gtctccaccg gcgtcaaacc gatgggcatt accgaaggcc
    40681 cgtataacgg taaaccgaac ccgcacgcct ggatgtcggc agaaaacgcg ctgatttatg
    40741 tcgataacat tcgcgacgcc ctggtgaagt acgatccgga taatgcgcag atctataagc
    40801 aaaatgccga acgctataaa gcgaaaattc gccagatggc cgatccgttg cgtgccgagc
    40861 tggaaaaaat tcccgccgat cagcgctggc tggtcaccag tgaaggcgcg ttctcttacc
    40921 tggcgcgcga taacgacatg aaagagcttt atctctggcc aattaacgcc gatcaacagg
    40981 ggacgccaaa acaggtgcgt aaagtgattg ataccattaa aaagcaccat attcccgcca
    41041 tctttagcga gagtacggtt tccgataaac ccgcccgcca ggtcgcgcgt gaatccggcg
    41101 cgcattatgg cggcgtactg tatgtcgatt ctctgagcgc cgctgacggc cctgtgccaa
    41161 cctatctgga tctgctgcgc gtcacgaccg aaaccatcgt caacggcatt aacgacggac
    41221 tgaggagtca acaatgagtc aatctgcgat taccgttgat caagtcacgg tgacgtatcg
    41281 caacggtcat accgccctac gggacgctac ttttcaggtg cctggcggtt caatcgccgc
    41341 gctggtaggc gtaaatggtt ccggtaagtc tacgttattt aaagcgttaa tgggctttgt
    41401 gcatcttgcg cggggcgata tcactatcct gcaacagtca gtcaaccagg cgctgaaaaa
    41461 aaacctcatt gcttatgttc cacaatcgga agaagtggac tggtcatttc cggtactggt
    41521 agaagatgtg gtgatgatgg gacgctacgg tcatatgggc tggctacgcc gtcccacagc
    41581 gcatgatcac gcctgtgttg acgccgcgct ggcgcgggtg gatatgcagg aatatcgtca
    41641 caggcagatt ggcgagctgt ccggcgggca gaaaaaacgt gtgtttcttg ccagggccat
    41701 cgctcaggat ggacaggtaa tcctgctgga tgaacctttt accggcgtgg atgtaaaaac
    41761 cgaagcgcga atcatcgatc tactgcggga actgcgcgat gaaggccgca cgatgctggt
    41821 ctcaacgcat aatctcggct ccgtcaccga attttgcgac tatacggtaa tgattaaagg
    41881 aaccgtactg gccagcggcc ctaccgaaac cacgtttacc gccgcgaatc tggaactggc
    41941 gtttagcggc gttctacgtc atatcgcgct aagcggaggt gaagagcaca tcatcaccga
    42001 tgacgagcgc ccctttattt cccgacgcgt ggccagcgga ggaaaatcgt catgaactgg
    42061 cttgttgagc cgtttggcta ccagtatatg ctcaacgcga tgtgggtctc cgcgatggtg
    42121 ggcggtcttt gcgcgtttct ctcctgctat ttgatgctca aaggctggtc gctcattggc
    42181 gatgcgctat ctcactctat tgtgcctggc gtcgctggcg cctggatgtt agggctgccc
    42241 ttctcgctcg gcgcgtttct ttccggcgga ctggcggcag gcagtatgct ctttcttaac
    42301 caacgctcac gcctgaaaga agacgcgatt atcgggctta tcttctcctc tttttttggc
    42361 gtcggccttt ttatggtgtc gctcaatccg atgtcggtga atatccagac gattattctc
    42421 ggcaacgtgc tggcgatcgc gccagcggat attacgcaac tggcgattat cggcgcagtc
    42481 tcgctgacga ttctgctgtt aaagtggaaa gatctgatgg tcgtcttttt cgatgagacc
    42541 catgcgcgtt ctatcgggct taatccgggt cgactaaaat tgttgttttt cactctattg
    42601 tccgtctcta ccgtggcggc cctgcaaacc gttggggcgt tcctggtgat ctgtctcgtc
    42661 gtcacgccgg gcgcgacggc ctggttactc accgaccgtt ttccacgtct gctcatgatt
    42721 gccgtcgtga ttggcagcct gaccagtttt ctgggcgcat ggcttagcta ctggctggat
    42781 ggcgccactg gcggaattat tgtcgtcatg caaaccttac tgttcatcac ggcctttatt
    42841 ttcgccccga aacacggtct gttagccaac cgtcgacgcg cccgcctgca gaaggagccg
    42901 acatgttctt agcaacgtta ctggaaccct ttcagtttga ttttatggtg aacgccctta
    42961 tggtttcggt cattgtggcg attccctgcg ccttgctgtc cgtgttttta gtgttaaaag
    43021 gctgggcgtt aatgggcgac gcaatgagtc atgcggtatt ccccggggtc gtgctggcat
    43081 atattgtggg gattcccctg gcgattggcg ctttcattgc cggattattt tgcgctatcg
    43141 ccaccggtta tctggacgat aacagccgca tcaaacgtga tacggtgatg ggcatcgtct
    43201 tttccgggat gtttggcgca ggtctggtgc tctatgtttc tattcaatcg gaagtgcatc
    43261 tggatcacat cctgtttggg gatatgctgg gcgtatcgct gggggatatc gtacaaacgt
    43321 cggttattgc actgggtatt gcgttaatca tagggctgaa atggaaagat ctcctgctac
    43381 acgcttttga cccgcaccag gcgaaagcca gcgggctgaa tacgacgcta ctgcattatg
    43441 gcctgctatg tatgattgcg ctgactatcg tcgccacgct gaaatcggtg ggcattattc
    43501 tgtcgatttc attgcttatc gcccccggcg caattgccat tttgctgacg cgacgctttg
    43561 cgcgcgcgct gggattagcg gtgagtctgt cagttattac cgcttttgcg ggcgtctatc
    43621 tgtcttttta tcttgatagc gcgccagcgc cgaccatcgt ggtattattt gccatcgtgt
    43681 ttattgcggt atttatttac gcaacatggc gcgacaggcg taatgaaatc gtaccagagg
    43741 cgcaaggtta acagcagcgt tcagaaaata aatacgacag ttgtagtaga aagccaccct
    43801 atatctgttg ttggtcagta tggtaagcag ctatctttaa atttctttac aacaagcgta
    43861 aagataagct gctttactcc ccatgttttt cctgtttcga aattttttca gagtttggct
    43921 aacccagcat aatgtgatta ttactcacaa gatctgtaat atcccagcaa aaaataaatt
    43981 tataactaca cgtaatacaa gagagtgatt gtcacataaa aaatagttta attcattcct
    44041 actgcaatcg gtaacgcgca attatcgtca ggtacagcag ggttatgtgc aaaagcagtg
    44101 cgctgtaaat gcgcgtctag tttcagtccc cgaaacagag atagcggtga agagtccatc
    44161 cccaaacgat acataacctt cttacgataa atactgacgg tttttgttcc cagaccaaat
    44221 tttttcgcca gttcaattgc cggatgtccg gaggataata atatcagcag cgcatatttc
    44281 gcctgcgtga caccgggagg tagattccac caggcgtatt gattgatatt aaacaatacc
    44341 tcttccggcg tctcgccggc attaaaagca tacgtagcag ccacggtttt cttttgtggc
    44401 ctgtggcaga aacgcagcca ggcttccgga agacggagct tctctcgctc cgagcggata
    44461 gcgcaggata gttcgtcttt taaaacataa tccataacgc caaaatattg cagcacacag
    44521 cgatcgatat aatacaagcg atctgccact accaaaactt tacggttctg caaccgcgcc
    44581 tgcaacgcat gaaaaagata aacatgctca tgcgggttca aagctaaaat cagcccggcg
    44641 tccggcatat cggatagaga atgcaaaagt gcggttaatg agttacacgt tttaacgcac
    44701 ttttccggat atttttgctt aaaaatagac tgtagggcat aacaattagt ccagttaata
    44761 ccgtatataa ttacatttct catttattta tccttttttg aaaactgacc acagcttcgg
    44821 taatgatttt tcttcctggg cgactactgc gcaagtagat aacgccctct tactacaaag
    44881 gtaataagac cagatacgtt attacatgcg caatgtcgtt accgaaatga attcctttta
    44941 caaatctgat aatgattaaa tttgctgttt tactttactg taatctctta gagtacaacg
    45001 attgcctgac gccttgtggc catgtatgtc tgacaatgaa cgctttcggt tccctttcat
    45061 tagctacata tcactggtgt agcgatactg aaatatacac tacgattaaa aaaatatttg
    45121 gtatctgtaa cgcaaacaga tagtaacgtt taaaataatt tcacaaatca atggttcatt
    45181 gtacgcataa agctaagcgg tgtaatctta aaatgccgtt taaaaatagc gataaaataa
    45241 gaaggcgtat catagccaca catcgtcgcg acttgtgaaa tatttccagc acccatacgt
    45301 aataatttta tagcctgatt catacgagca tccaagtata ttttgctaaa actcacctct
    45361 tcagcggcca gttttcgctt cagacttgat acgctcataa acagctttcc tgccacctca
    45421 gcctgtgacc atttgcgggt gagatcgctg ataataatgt tataaacttt ctcttttgtt
    45481 gtaattttta ttgctcgctc aaggaaatca aacccaccgg gcttacgtac aaatgccgat
    45541 ataagataca tcaatgagaa atatgaataa tcatgatcat caatactcac attactacaa
    45601 acccgtggac atgcgacacc atgcaaaata gagtcaaaag tatcactcat ccctggcaac
    45661 aagtccgcat gaaaaaaata ctttggtttc gtttttaatg atagctctcg atcattatag
    45721 tttcttgtac tgtaaaaaac tttgtagaat ttttgcatta agtcatagga aacttccagt
    45781 gaagaaaaat caatatgtcc ttctatttcg ctcatactaa gcgtgattgt ttgatctttt
    45841 tccaataaaa ataaacacag cgcagattgt tcgatgaact ccccaaattc gttttcaatt
    45901 cgcaaactgc ctttattaag tttaaacaat aagcagtttg cgacataata gtctcttacg
    45961 tcagctaatc catttattaa tggaaatttg ttcggttgtt gaaggtgatt attgctaatg
    46021 gcctcaactg atttattcat tgaaggcaat accatatttt atcctgtgtg ctataaggaa
    46081 ctcaaaatcg ttatattctt ataaacaaat aattaaaact cacagagatg atttaaatcc
    46141 gattttttta ttattatagc caataattac attccaaagc gcgttcattt cgtcacaaaa
    46201 agataccctt acaaacttta tgcacaattt tgtaataaaa gcttacaata ttaatataat
    46261 cctttcagaa taaaacgcct ggcagatacc ttaataatcc atatacatca ataagataga
    46321 tacactggca tggtgcattt tctgcattat ttgctgatat atacaccata ccttatcaca
    46381 aatcgccagc aatggggggt tcaccagtca attgcctctt tgttttcccc gcccgataaa
    46441 ataatctcct gcatccagga ggtcatttgt gactgtgcat tcattgtacc aactaatacc
    46501 ccgtttaaag cctcatataa atgggtgccc ggttcaactt ttgctaacat gttttgtagc
    46561 atagccgttt gctgctcaaa agaaacaaaa gccgaatcac cacttttagg atctttgaag
    46621 gcattcatct cttgataaat gctatcttta agcgtttcag aagaggctga ctcaggaagc
    46681 gccaaaagtc gttggtagaa tgcatcataa agatcaacgt cgccgccatt gcttaaaggc
    46741 gcgctatcca cattattcag catagcggcc ctggcactca acgaaaccac acccgtcact
    46801 tcagtatccg ctgtcgggac caaataagaa gtcggaatcg tacccggtat caccttataa
    46861 cctccatttt acaatgcttg cgtttttgtc ttccattcat caataagtgc gttaatggcg
    46921 ttatcagaaa tcgtccggca gtcttgtgga agttcatcaa gatgatgctt aatgacgcct
    46981 actgctgttt caacaaattg ttcaggtgaa aattctgcga tctgatcgcc gcaactcatg
    47041 ataaagcgct gttcctgatg atatttaaga ttaaaagtgc caggccagtt ctccataagc
    47101 aacaccatca gtttttggtg ttcttttttc gcattaactg gcagtgttaa aaaaagttgc
    47161 ccctccggct tatcgaaatc ccttagccac tcatccagga cggttaaaag cgtttcggga
    47221 tggtcgaccg ctgctgaaaa taactcgcgg gcataaatct gtattttttc catccacttc
    47281 caggccattg tctgattatc agtaagataa gcggcgacct gctgtaacgc gtctatcatt
    47341 ccctgctcgt aaccttcctg ataggcgtac atccgcaagg tctttgcctc ttcttccgcc
    47401 tctcgcaaaa tacgcttagc ccgttggtgc gcctgctgtt ctaatctttc aatagagaaa
    47461 taacgttcca gcgttttacg ctttatcagt atcccctcaa caggcgaaag cggggacgga
    47521 attgggatat ttttgagcat attgtaaggc cagtagcaaa attgacattt ctacagcatc
    47581 ctgcttcaat gcctcctcaa taaatggagg aaaaagcaaa ggaaaacgct gtgctaaaga
    47641 ttcaggtaaa aattcattca gggcatttaa ctgtgcatac ccgacgctaa gtaaaaacct
    47701 gtgattcggc gccttattgc aaacggataa acttgttccc tgatgcattg ccaaaaatgc
    47761 ttgcgcccaa tccggcaggc caagcaaggc tccctgcctt gccagatcgg ctctcagttt
    47821 atggcaaccg agtaaatacg ctacttgcgg cagtcggcgc cactgacgca gccacagctg
    47881 cgtcagtgag ttttgaatac actccttttc tccgttctta agccgccatg tcgccagtat
    47941 taactcattt gccgccgccc tggcggcggg tctgacaatc atttccggcg ctatctgcaa
    48001 ccgctgagga tggatatacg ataacggatc aaaaatgatt ctttgccaga taatgggtaa
    48061 tggctgccta ttcatttgac gatttcgcct tatcatcagc cgttatgcct ttcttattgc
    48121 gggcataatg gtttttgtaa taccagacgc cagagcctgc tgacatcacg gataacaaaa
    48181 taatcaacac aatccaactg gttgcaaaag aattacgttt tactggtgtg ccgggagcct
    48241 gtaattgggc atcagaacgt tctgacaaca caacagaaat gttgtcataa tccacatcgg
    48301 caaaactatt ctttaagaaa cgcttgatat cgctgatctg atgcgcaagc ggcgaacctc
    48361 gttcatatac ggctaatgcc gacagatgaa caggttttgg cggacggcca ttttcaccag
    48421 catcaatatc ataactaata tggaccctgg cggagagcac gccctccatc gtctgtaatg
    48481 actgttccag tcgctgttca atagccgaat ataacctggc cttttcagct cgcggagacg
    48541 ataccagcga atccgccggg aacatctgcg ctatttccac ccgtggccgg ggaggaagct
    48601 gataagtttt aatccagtac accgcagcgg taaaatcagg ctcagcaacg gtaatgctat
    48661 agcccaattt tccgctatca attttattcg cctctatatt gtgcatttgc agaacggcaa
    48721 tgacctcatt agcctgttcc tggtccagtc cttttaaaag atccttatcc ttacagccgg
    48781 caagggtcat taccagcaga aaggtatata gatatcgacg aatcatgagc gtaatagcgt
    48841 ttcaacagcc ccgactcctt tacgagtaag ggtacttacc atagaaacat acaggttata
    48901 atctgaaatc atctcttgcg aaatagccag ctcattagga tccgtcacca gattagggtc
    48961 ctcaatcctg ttggtaatcg tctgtttatc cacagccgtg gcaatcgccg aaccagaaaa
    49021 agcctggagt agccggtcat ccagcgagac aatgtccgtt tccataggcc tgatattgac
    49081 cgcctgccct ataacggcat tctcagggac aatagttgca atcgacataa tccaccttat
    49141 aactgattaa cggaagttct gaataatggc agcatcaata tccttaaaga cttttaccgt
    49201 gttcgattgc gcgttacggt acaagttata ttccgagagc ttactctgat acgccgccag
    49261 tagcgccgga tcggagggtt ttgctgctaa tttatccagc gcctctgtta cctgcgtttg
    49321 tagattatca acgcccttat caaattttgc tgaaacttca tccagatagc ctgaccaaga
    49381 tgttggcata atgacttcct tatttgcgtt aaattaaagt gggcttggga aataccaatg
    49441 gcctgggctc attttgatat aaccttccgc cccgtactga aatgagcgcc ccttgagcca
    49501 gtcatctttt aattcgatcg caaactgcac atagcgtcct ccccatgtgc ggtaatagct
    49561 atcgacaaat tgacgggctc tgagtatttc tacatcatcg agcgccccct gaataacaaa
    49621 cgttacgccc cccttatgat tcctgcggga ataaggtaac gcctgctgtt ttagccccgc
    49681 ttccgcctgg cctgcggcgg taacatcgtc catcaatgtg atgttaaccg aatccgcgta
    49741 aggcattagc gctctcagct tttgacttaa cacctcgagc tctttcttgc tcatcgtgtt
    49801 tcgctggcgg cttagccaga aaacgggttt acgcggctca tcgaaatgaa gccgataata
    49861 agccagctgc ggataatagg tatccagcca ggtagagata cgcttatttt cttcgttttc
    49921 gttaatcact cgcgcatttt tatcataatc gcccctcgct aaaacctgac gagcccacag
    49981 cgtatctctt tcattttgcg cagcgacata gagcattttg tcccgtcctg gcaacacctg
    50041 aaagcgctcc ttctcctgcc ccaataacga atcgagctct gcggcctgcc gctgcggcga
    50101 gttaagtatc cataacgtcc ccaccgtccc aattcccaat ataaaaaacc cggccagtgc
    50161 tgctacaatt ccgtttttaa aacgcggctc gttctttttt gcagacgttt ctaacttctc
    50221 aggctgctcg ggcacccacg gctcgctttc cgggcgaatc aggataagca attcaccgac
    50281 ctgtattggc gtatttaatt gcaccgaacg agattcagga tttccttctt tcagctcatg
    50341 gagtataatt tcggtcgcat ccgtatccac ctggatttca aaatttactc cgccatggtc
    50401 cagcgggata aaaaagctat cggcaggtat atcagggagt tggcctgaag cagtgagcgc
    50461 atcactctga cctaccacaa agagtgttcg gcctgtcagc aatggaaact cacagccgtt
    50521 cagtgagctg ttaagtaatc gaactatgta tggccctggg cttgttatcg tcttctcttt
    50581 tgatgtttcc atatatactg ttagcgatat ctgtcgttct cgatagcagc agattaccgc
    50641 acaggacaca gggattcctg atgaaaatag aatgaaaagt gagaaataaa atcaatttat
    50701 tctgtataat gcgtctcaac acatattaaa agaaccatca tccccattgg ggcttaaact
    50761 actgtagata aattacccaa atttgggttc ttttggtgta acaatcagac cattgccaac
    50821 acacgctaat aaagagcatt tacaactcag attttttcag taggatacca gtaaggaaca
    50881 ttaaaataac atcaacaaag ggataatatg gaaaatgtaa cctttgtaag taatagtcat
    50941 cagcgtcctg ccgcagataa cttacagaaa ttaaaatcac ttttgacaaa tacccagcag
    51001 caaattaaaa gtcagactca gcaggttacc atcaaaaatc tttatgtaag cagtttcact
    51061 ttagtttgct ttcggagcgg taaactgacg attagcaata atcacgatac gatttactgt
    51121 gacgaacctg ggatgttggt gctcaaaaaa gagcaggtag ttaacgtgac gcttgaagag
    51181 gtcaatggcc acatggattt cgatatactc gagataccga cgcaacgact tggcgctctc
    51241 tatgcactta tcccaaacga gcagcaaacc aaaatggcgg tacccacaga gaaagcgcag
    51301 aaaatcttct atacacctga ctttcctgcc agaagagagg tatttgaaca tctgaaaacg
    51361 gcgttctcct gtacgaagga tacaagcaaa ggttgcagta attgtaacaa caaaagttgt
    51421 attgaaaatg aagagttaat tccttatttt ctgctgttcc tgcttactgc ttttctccga
    51481 ctccctgaga gttatgagat catccttagc tcggctcaga taacgttaaa gaagcgcgtt
    51541 tacaacatta tatcttcgtc acccagtaga cagtggaagc ttacggatgt tgccgatcat
    51601 atatttatga gtacgtcaac gctcaaacgg aaacttgcag aagaaggtac cagctttagc
    51661 gatatctact tatcggcaag aatgaatcag gcagcaaaac ttttacgcat aggcaaccat
    51721 aatgttaatg ctgtagcatt aaaatgtggt tatgacagca cgtcctactt cattcaatgt
    51781 ttcaaaaaat attttaaaac tacgccatcg acattcataa aaatggcgaa ccattaacat
    51841 ttttgtatca gtcactcaag taaagatttt tattaaaatt ttaataattt aaaattcaga
    51901 ccgtgcatta acacgctata tcaggatggg aggctattca acatcattgt tctgtccgga
    51961 agacagctta tactgatatc tctggtaatt taaagtaagg ctgattatat aacacgattt
    52021 ttgtgaactt gtcatcgcta tgatgactgg taaaccgata ttgccttatt cacagcgtaa
    52081 gaatccgtcc agatgacact atctccttcc ggctttaacc ctatggatta aggccggcat
    52141 tttattcata tttatacatc atccgttccc tctgagaact atttgcctga acggtctaca
    52201 ccgaaacagt cacgcttgtt agctttctgc caggcataca tcttctcttc atcctgatat
    52261 cgatataatg cctgggggcc agcttgagga tga
//
LOCUS       DAJVKX010000017        52114 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000017 DAJVKX010000000
VERSION     DAJVKX010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 52114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52114
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.017"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            313..945
                     /gene="fimZ"
                     /locus_tag="OPY25_000953"
     CDS             313..945
                     /gene="fimZ"
                     /locus_tag="OPY25_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HCS0926622.1"
                     /translation="MKPASVIIMDEHPIVRMSIEVLLGKNSNIQVVLKTDDSRTAIEY
                     LRTYPVDLVILDIELPGTDGFTLLKRIKSIQEHTRILFLSSKSEAFYAGRAIRAGANG
                     FVSKRKDLNDIYNAVKIILSGYSFFPSETLNFISNTRPPKGGHHDMPLSNREVTVLRY
                     LANGMSNKEIAEQLLLSNKTISAHKANIFSKLGLHSIVELIDYAKSHELL"
     gene            complement(991..1509)
                     /gene="sfmF"
                     /locus_tag="OPY25_000954"
     CDS             complement(991..1509)
                     /gene="sfmF"
                     /locus_tag="OPY25_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HCS0926623.1"
                     /translation="MILRRVFIAIGCVLLSPLSQANSSLGEVNIELRGNVVDFTCAVV
                     AGDSNKSVNLGTWPTKQLHVAGDATQPVAFSLKLEGCPPGSASITFSGTPAPGTALLA
                     LADTAMAQKLAIEIRDGDQRRLPLEQASKAVDIDNNGNATLKFYANYIALADGVQPGL
                     ANADATFLINYN"
     gene            complement(1519..2526)
                     /gene="fimH"
                     /locus_tag="OPY25_000955"
     CDS             complement(1519..2526)
                     /gene="fimH"
                     /locus_tag="OPY25_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrin D-mannose specific adhesin FimH"
                     /protein_id="HCS0926624.1"
                     /translation="MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFT
                     SGNNQPGQVVTLLKKSDWCGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLND
                     YLLGAMSITDSVAGVFYPPRNYIRMGVDSNVSQQKPFGVQDSKLVFKLKVIRPFINIV
                     TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGAPL
                     FSQAGAGNRPQGVTPQAKTIAIKCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVV
                     ANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPAEGPFTARGYLRVDY
                     D"
     gene            complement(2541..5153)
                     /locus_tag="OPY25_000956"
     CDS             complement(2541..5153)
                     /locus_tag="OPY25_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HCS0926625.1"
                     /translation="MKKTTWFAGRFPGYVSPLSGVALSVLAALCPLTSRGESYFNPAF
                     LSADTASVADLSRFEKGNHQPPGIYRVDIWRNDEFVATQDIRFEAGAVGAGDKSGGLM
                     PCFTPERIKRLGVNTAVFPVSDKGVDTTCIHLPEKIPGAEVAFDFASMRLNISLPQAS
                     LLNSARGYIPPEEWDEGIPAALINYSFTGSRGTDSDSYFLSLLSGLNYGPWRLRNNGA
                     WSYSKGDGYHSQRWNNIGTWVQRAIIPLKSELVMGDSHTGNDVFDSVGFRGARLYSSD
                     NMYPDSLQGYAPTVRGIARTAAKLTIRQNGYVIYQSYVPPGAFAITDLNPTSSSGDLE
                     VTVDEKDGSQQRYTVPYSTVPLLQREGRVKYDLVAGDFRSGNSQQSSLFFFQGTVIAG
                     LPAGLTAYGGTQLADRYRAVVVGAGQNLGDWGAVSVDVTHARSQLADDSTHQGQSLRF
                     LYAKSLNNYGTNFQLLGYRYSTRGFYTLDDVAYRSMEGYDYEYDSDGRRHKVPVAQSY
                     HNLRYSKKGRFQVNISQNLGNYGSLYLSGSQQNYWNTADTNTWYQLGYASGWQGISYS
                     LSWSWSESVGISGADRILAFNMSVPFSVLTGRRYARDTILDRTYATFNANRNRDGDNS
                     WQTGVGGTLLEGRNLSYSVTQGRSSTNGHSGSASASWQATYGTLGVGYNYDRDQHDYN
                     WQLSGGVVGHTDGITFSQPLGDTNVLIKAPGAKGVRIENQTGVKTDWRGYAVMPYATV
                     YRYNRVALDTNTMDNHTDVENNVSSVVPTEGALVRAAFDTRIGVRAIITARLGGRPLP
                     FGAIVRETASGITSMVGDDGQIYLSGLPLKGELFIQWGEGKNARCIAPYALAEDSLKQ
                     AITIASATCIRPSS"
     gene            complement(5184..5876)
                     /gene="fimC"
                     /locus_tag="OPY25_000957"
     CDS             complement(5184..5876)
                     /gene="fimC"
                     /locus_tag="OPY25_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HCS0926626.1"
                     /translation="MLNSIKLGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTS
                     LAISNSDTQERYLVNSWIENNAGQKEKTFIVTPPLFVSEPKSENTLRIIYAGQPLPED
                     RESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
                     VGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGSVTFQTVNDY
                     GALTSATTASLG"
     gene            complement(5920..6453)
                     /gene="fimI"
                     /locus_tag="OPY25_000958"
     CDS             complement(5920..6453)
                     /gene="fimI"
                     /locus_tag="OPY25_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein subunit FimI"
                     /protein_id="HCS0926627.1"
                     /translation="MIRKGAALVGLVLMSPVIAQPVMVESGRVHLRGQLVNGGCAVAT
                     ESQDLRVLMGQYRTNAFTGPGSFAPVSVPFSLRLISCSAEVWRHVGIAFAGVTPAEDP
                     HVFLASGEGIGNAGIGLALFDDQQRQIIPNTLPLHYAPILTSEMTLHFTARYRAISEN
                     MTPGRIHSEVWFTLVYP"
     gene            complement(6528..7082)
                     /gene="fimA"
                     /locus_tag="OPY25_000959"
     CDS             complement(6528..7082)
                     /gene="fimA"
                     /locus_tag="OPY25_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459538.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein subunit FimA"
                     /protein_id="HCS0926628.1"
                     /translation="MKHKLMTSTIASLMFVAGAAVAADPTPVSVSGGTIHFEGKLVYA
                     ACAVSTKSADQTVTLGQYRTASFTAIGDTTAQVPFSIVLNDCDPKVAATAAVAFSGQA
                     DNTNTNLLAVSSADNSTTATGVGIEILDNTSSPLKPDGATFSAKQALVEGTNTLRFTA
                     RYKATAAATPGQANADATFIMKYE"
     gene            7629..8495
                     /gene="folD"
                     /locus_tag="OPY25_000960"
     CDS             7629..8495
                     /gene="folD"
                     /locus_tag="OPY25_000960"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HCS0926629.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACDEVGFVSHSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLP
                     AGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPG
                     EWIKEGAIVIDVGINRLENGKVVGDVVFDEAAARASYITPVPGGVGPMTVATLIENTL
                     QACIEYHDPQGK"
     gene            8497..8709
                     /gene="ybcJ"
                     /locus_tag="OPY25_000961"
     CDS             8497..8709
                     /gene="ybcJ"
                     /locus_tag="OPY25_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HCS0926630.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIADGLVKVDGA
                     VETRKRCKIVAGQTVSFEGQSVNVVA"
     gene            8793..9341
                     /locus_tag="OPY25_000962"
     CDS             8793..9341
                     /locus_tag="OPY25_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001728132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCS0926631.1"
                     /translation="MPTVITHAAVPLCLGAGLGLKVIPPRLLFAGVVLAMLPDADVLA
                     FKFGVAYGNVFGHRGFTHSLLFAFVLPLLCVLAGRRWFRAGQVRCWLFLTVSLLSHSL
                     LDSITTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSSYITPYGHQVIVSELLWVWLP
                     GGVLIGILGWHRWRIGDEKRTR"
     gene            complement(9432..10817)
                     /gene="cysS"
                     /locus_tag="OPY25_000963"
     CDS             complement(9432..10817)
                     /gene="cysS"
                     /locus_tag="OPY25_000963"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCS0926632.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDA
                     LNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDL
                     EQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAG
                     GEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLG
                     LLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLTEMGIILE
                     DGPQGTTWRRK"
     gene            10990..11484
                     /gene="ppiB"
                     /locus_tag="OPY25_000964"
     CDS             10990..11484
                     /gene="ppiB"
                     /locus_tag="OPY25_000964"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HCS0926633.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEAIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     ADNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIENV
                     TVSE"
     gene            11487..12209
                     /gene="lpxH"
                     /locus_tag="OPY25_000965"
     CDS             11487..12209
                     /gene="lpxH"
                     /locus_tag="OPY25_000965"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HCS0926634.1"
                     /translation="MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFE
                     AWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKV
                     LDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRPFLTLPLFIRRRIAARMRAGS
                     KAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANGQPAFRVVLGA
                     WHHEGSMVKVTPDNVELIAFPL"
     gene            12327..12836
                     /gene="purE"
                     /locus_tag="OPY25_000966"
     CDS             12327..12836
                     /gene="purE"
                     /locus_tag="OPY25_000966"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCS0926635.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILDVPHHVEVVSA
                     HRTPDKLFSFAETAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDSALHRRIADWRKAQTDEVL
                     ENPDPRGTL"
     gene            12833..13900
                     /gene="purK"
                     /locus_tag="OPY25_000967"
     CDS             12833..13900
                     /gene="purK"
                     /locus_tag="OPY25_000967"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCS0926636.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLGLATAPWQLLSS
                     ADEWSGIFDRLGELAIIKRRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSG
                     EVSLVGARAHDGSTVFYPLTHNLHQDGILRTSVAFPQANAEQQEQAESMLSAIMQALN
                     YVGVMAMECFITPEGLLINELAPRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVI
                     NAPSVMINLIGSELNYDWLKLPLVHLHWYDKAVRPGRKVGHLNLTDSDTSRLSATLEA
                     LSPLLPGEYASGIIWAQSKLK"
     gene            complement(13941..14834)
                     /locus_tag="OPY25_000968"
     CDS             complement(13941..14834)
                     /locus_tag="OPY25_000968"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCS0926637.1"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIADAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKAVEPYPLDVLVAESQGMIGYMLAQRLALEPDMPPVT
                     AVLTRIKVSADDPAFLEPEKFIGPVYSPEEQMALEATYGWHMKRDGKYLRRVVASPAP
                     RQIIESTAIELLLKEGHVVICSGGGGVPVAGEGEGVEAVIDKDLAAALLAEQIAADGL
                     IILTDADAVYEHWGTPQQRAIRQASPDELAPFAKADGAMGPKVTAVSGYVKRCGKPAW
                     IGALSRIDDTLAGRAGTCICL"
     gene            complement(14838..15647)
                     /locus_tag="OPY25_000969"
     CDS             complement(14838..15647)
                     /locus_tag="OPY25_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HCS0926638.1"
                     /translation="MKRIHPLMASRQSADYRQPWQMSGVWRRSINFVAKSGELLTLHR
                     RGSGFSPGGWILRGGDFDALRDVLTDGEKPQLTAAGIQIGEFLLCEPERRCSLRVPRY
                     LASPRLNATYMQRSEETGLFGPLTVAAAQPLCPELRQFCHCFQSALAGAATDWRLWLG
                     KGPGLTPSHEDTLTGMLLAAWYFGAIDERAGRNFFAQSGSLDRATTLVSVSYLRYAAM
                     GYFASPLLHFIHALRRDARTETAIDGLLALGHTSGADTLLGFWLGQQIVKG"
     gene            complement(15659..16918)
                     /locus_tag="OPY25_000970"
     CDS             complement(15659..16918)
                     /locus_tag="OPY25_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HCS0926639.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVKPASSLISVLNQGKTLLH
                     AGPPMRWQEMTGPMKGACIGACLFEGWAKDEMSALALLEQGKVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENITDGNRAYCNLNEGIGKVMRFGAYGEDVQQRLRWMRDVLMPVLS
                     AALGRLERGLDLTAMMAQGITMGDEFHQRNIASSALLMRTLAPHIARLQHDKQQIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAQIRAGSIVTAMTRNGDMFGIRVSGLGDRWFT
                     APVNTPQGLFFTGFSQDQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAK
                     SVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGVS"
     gene            complement(16928..18592)
                     /locus_tag="OPY25_000971"
     CDS             complement(16928..18592)
                     /locus_tag="OPY25_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HCS0926640.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKS
                     LLETTGFWHDDFHGATPNDICVAIRTEAVDDGITQVIVRQLEEALQQLAQGSSGSQSL
                     IQVRRWESACQKLPEANLALVSVAGEYAAELAEQALARSLNVMIFSDNVTLDDEIRLK
                     RRARDKGLLVMGPDCGTAMIANTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSAEVGGISALTALDILSADEKSQVLAFVSKPPADAVRQHIIAAMK
                     ATGKPVVALFLGFSSPVAREENVWFASTLDEAARLACLLSRVTSQRKEMVSTGGVIRG
                     LYTGGTLAAEAAGLLAGYLGVATDTEHHHGMMLDADGHQIIDLGDDFYTVGRPHPMID
                     PALRNQLIAGLGAQPQVRVLLVDVVIGFGATADPAASLIQAWQKACAARASDQPLFAI
                     ATVTGTERDPQCRSQQIAALEDAGITVVDSLPEATLLAAELIRPTLSSTHPSAPRLLE
                     AVAVINAGLRSFALDLQAAGMPVVHYQWAPVAGGNKKLARLLERLQ"
     gene            18908..19957
                     /gene="allD"
                     /locus_tag="OPY25_000972"
     CDS             18908..19957
                     /gene="allD"
                     /locus_tag="OPY25_000972"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HCS0926641.1"
                     /translation="MKISRETLHQLIENKLYKAGLKREHAAIVADVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPTFRIENTGPCTAILHADNAAGQVAAKMGMEHAIEIAK
                     KNGVAVVGISRMGHSGAISYFVRQAAREGLIGLSICQSDPMVVPFGGADIYYGTNPLA
                     FAAPSEGDDIITFDMATTVQAWGKVLDARSRNESIPESWAVDKNGAPTHDPFAVNALL
                     PAAGPKGYGLMMMIDILSGILLGLPFGRQVSSMYEDLHAGRNLGQLHLVINPAFFSSC
                     ELFRKHISQTMQELNSVKPAPGFKQVYYPGQDQDIKQKNADMNGIDIVDDIYQYLISD
                     ALYLKSYETKNPFAQ"
     gene            19979..21214
                     /gene="allC"
                     /locus_tag="OPY25_000973"
     CDS             19979..21214
                     /gene="allC"
                     /locus_tag="OPY25_000973"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HCS0926642.1"
                     /translation="MIKHFRHAIEETLPWLSSIGADPTGGMTRLLYSPEWLETQQQFK
                     KRMAESGLETRFDDVGNLYGRLCGTQFPEQVILSGSHIDTVVNGGNLDGQFGALAAWL
                     ALDWLKATYGAPLRTVEVVSMAEEEGSRFPYVFWGSKNIFGLANPEEVRYIQDAKGTG
                     VVDAMQACGFTLPAAPLAARTDIRAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVHAFSRICSQSIEKAKQHGDPLVLTFGKVEPQPNTVNV
                     VPGKTTFTIDCRHTDAAVLREFTEQLENNMRAICDEMDISIDIDLWMDEAPVPMNAEL
                     VAALTRLCETEQLNYRIMHSGAGHDAQIFAPRVPTCMIFVPSINGISHNPAERTNIND
                     LAEGVKTLALMLHQLAWQK"
     gene            21225..22010
                     /gene="allE"
                     /locus_tag="OPY25_000974"
     CDS             21225..22010
                     /gene="allE"
                     /locus_tag="OPY25_000974"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HCS0926643.1"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNYALLTPDGLVKNIIPGFEN
                     CDVTILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVIAGNIEAKAEGKTFS
                     LTQGGYLYCPPGEMMTFSNAQTEDSQLFLYKRRYTPVEGHAPWLVSGNASQLERIHYE
                     GMEDVILLDFLPKELGFDMNMHILSFEPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WVPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVMI"
     gene            complement(22089..23237)
                     /gene="glxK"
                     /locus_tag="OPY25_000975"
     CDS             complement(22089..23237)
                     /gene="glxK"
                     /locus_tag="OPY25_000975"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HCS0926644.1"
                     /translation="MKIVIAPDSFKESLSADKCCQAIKAGFSTVFPDARYVCLPIADG
                     GEGTVDAMVAATGGKRVSVDVSGPMGEKVNGFYGLTGDGKTAIIEMAAASGLMLVAPE
                     ARNPLRASSFGTGELIRHALDAGIRHIILGIGGSATVDGGMGVAQALGVRFLDAQGTP
                     LGAEGGNLSRLASIDLQGRDPRISECRIEVACDVDNPLVGPRGAAAVFGPQKGATPEM
                     VETLENGLRNYARILHALTGRDMSQIPGGGAAGGMGIAAIVFLEAEMKPGIEIVMQAV
                     KLEEAVKEASLVITGEGRIDSQTAGGKAPIGVASVAKRHHVPVIGIAGVLGDGVEVVH
                     RHGIDAVFSILPRLAPLPEVLANGEQNLYHSACNIARVIKLGQDIGTR"
     gene            complement(23260..24558)
                     /locus_tag="OPY25_000976"
     CDS             complement(23260..24558)
                     /locus_tag="OPY25_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HCS0926645.1"
                     /translation="MFPVINRESVLSGFQWFFFIFCNTVVVPPTLLSAFHLPADNLLM
                     LTQYAFLTTALACLVQAFCGHRRAIMEGPTGLWWGAILTITLGEASRGTPLNDIASSL
                     SVGIAISAMVTIFIGISGLGHRLARLFTPAVMVFFMLLLGAQLTSIFFKGMLGLPFGI
                     ADTSARIKLAPFGLAVAVMCFILAMIIFLQQRISRYALLVGTVVGWGLWRLCFPSSHL
                     PPGELSWRWFPLGSHGTLMPGIIVTAVMTGLVNISNTYGAIRGTDIFYPHQGSGSSRY
                     RRSFMISGLMTLVTVPFAVVPFSPFVSSIGLLTQTGDSSRKSFICGSALCLLVAIITP
                     LTRLFCAIPLAISSAVMLVSYLPLLYSGLVFSQQITFTARNIYRLALPLFVGIFLMGL
                     PPVYLQDLPLMIRPLLSNGLLVGILLAVLMENLIPWERIK"
     gene            complement(24617..25978)
                     /gene="allB"
                     /locus_tag="OPY25_000977"
     CDS             complement(24617..25978)
                     /gene="allB"
                     /locus_tag="OPY25_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HCS0926646.1"
                     /translation="MSFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVL
                     DATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ETIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFYKGAQKLGEMDQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKAAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDQENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGG
                     IAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLKHKGRIAPGKDADLVFIQ
                     PDSSYVLKNEDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEHGFPVPPKGQFILK
                     HQQ"
     gene            complement(26057..27511)
                     /locus_tag="OPY25_000978"
                     /pseudo
     CDS             complement(26057..27511)
                     /locus_tag="OPY25_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
     gene            complement(27607..28854)
                     /locus_tag="OPY25_000979"
     CDS             complement(27607..28854)
                     /locus_tag="OPY25_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0926647.1"
                     /translation="MSETKKSGIDYWKQIVVVMSLGWVAIWIYRTVLTPIYPEIQASL
                     DNVSNAEIGAIASFYFFAYCSMQIPCGILVDKFGQKIMLMAGFTLFIIGTLCIAKANG
                     LAMIYTGSLMAGGGCASFFSSAYSLSSANVPQARRALANAIINSGSAIGMGIGLIGSS
                     VLVKNMSMAWQNVLYIVAAILVIMLCVFTLVIRGKAKSDSAQAEKQTQTVTEDEKRAP
                     LFSGLLCSVYFLYFCTCYGYYLIVTWLPSYLQTERGFDGGAIGLASALVAVVGVPGAL
                     FFSHLSDKFRNSKVKVILGLEIVAAAMLAFTVLSPNTTMLMVSLTLYGLLGKMAVDPI
                     LISFVSEQASAKSLGRAFSLFNFFGMSSAVVAPTLTGFISDVTGSKEISFVISACLVV
                     TGTLIFAAVTLYKKKATQRIASA"
     gene            complement(28920..29798)
                     /gene="glxR"
                     /locus_tag="OPY25_000980"
     CDS             complement(28920..29798)
                     /gene="glxR"
                     /locus_tag="OPY25_000980"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HCS0926648.1"
                     /translation="MKLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     NVETARQVTEFADIIFIMVPDTPQVEEVLFGEHGCAKTSLQGKTIVDMSSISPIGTKR
                     FAQRVNEMDADYLDAPVSGGEIGAREGTLSIMVGGEQKVFDRVKPLFDILGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALVFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMINRTFEPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SAMVQALELMANHKLS"
     gene            complement(29899..30675)
                     /gene="hyi"
                     /locus_tag="OPY25_000981"
     CDS             complement(29899..30675)
                     /gene="hyi"
                     /locus_tag="OPY25_000981"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HCS0926649.1"
                     /translation="MLRFSANLSMLFTEYDFLERFDKAAQSGFRGVEFMFPYDDDIEV
                     LKRKLRDNNLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPSGFSATEIYDTLVENLRYAANMLAKEDILLLIEPINHFDMPGFHLTGTQQ
                     ALVLIKDIGSDNIKIQYDIYHMQRMEGELTQTMTAWADKIGHLQIADNPRRGEPGTGE
                     INYDFIFNVIKQSDYDGWVGCEYKPLTTAEAGLSWINQYR"
     gene            complement(30688..32469)
                     /gene="gcl"
                     /locus_tag="OPY25_000982"
     CDS             complement(30688..32469)
                     /gene="gcl"
                     /locus_tag="OPY25_000982"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HCS0926650.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRAAAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRVQIEKALEMLIQSERPVIVAGGGVINAD
                     AAPLLQQFAELINVPVIPTLMGWGCTLDDHPLMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTQGRKIIHIDIEPTQIGRVLCPDLGIVSDAKAALTLLIDVAQ
                     EMQKAGRLPCRKTWVDECQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPQRNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGDE
                     LDNVTEFEEVADSAKDAPTETCFMKYE"
     gene            complement(32554..33372)
                     /gene="allR"
                     /locus_tag="OPY25_000983"
     CDS             complement(32554..33372)
                     /gene="allR"
                     /locus_tag="OPY25_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HCS0926651.1"
                     /translation="MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVS
                     DISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVA
                     GPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCI
                     ASAIYDDAGSVVAAISISGPASRLTEDRFISQGELVRDTAKDISTALGLKPPVA"
     gene            complement(33451..33932)
                     /gene="allA"
                     /locus_tag="OPY25_000984"
                     /pseudo
     CDS             complement(33451..33932)
                     /gene="allA"
                     /locus_tag="OPY25_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459510.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
     gene            34159..35085
                     /gene="allS"
                     /locus_tag="OPY25_000985"
     CDS             34159..35085
                     /gene="allS"
                     /locus_tag="OPY25_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HCS0926652.1"
                     /translation="MFDPETLRTFISVAETGSFSKAAERLCKTTATTSYRIKLLEENT
                     GVGLFFRTTRSVSLTAAGSHLLSQAKDWLAWLDSMPDELRQVNDGVERQVNIVVNNLL
                     YSPQAVASLLSWLNARYPFTQFHFSRQIYMGVWDSLLYEGFSLAIGVTGTEPLANTFM
                     LDPLGSVQWRFVMSADHPLAHVSGPLTEAQLRRFPAINIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFVPQPLCQTLIDKNELVSCTIPTMRPPSPLSLAWHKF
                     GGGKAVEDIVKLFTQRQPEIAGFLSIFNTVRC"
     gene            35155..36249
                     /gene="mnmH"
                     /locus_tag="OPY25_000986"
     CDS             35155..36249
                     /gene="mnmH"
                     /locus_tag="OPY25_000986"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HCS0926653.1"
                     /translation="MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMM
                     DDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQ
                     RSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVR
                     QQPNGVDLEGLARHRGSSFGRTLKPQLSQASFENKLAVELLKINARQTLKRWVLEDEG
                     RTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDGAGWQ
                     AYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYD
                     PMYRYQLEKKAANIVFRGTWQDVANWLKAQ"
     gene            complement(36288..36947)
                     /locus_tag="OPY25_000987"
     CDS             complement(36288..36947)
                     /locus_tag="OPY25_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0926654.1"
                     /translation="MDDLLPDLTLAFNETFQMLSISTVLAILGGLPLGFLIFVTDRHL
                     FWQNRFIYLVASVLVNIIRSVPFVILLVLLLPLTQLLLGNTIGPIAASVPLSVAAIAF
                     YARLVDSALREVDKGIIEAALAFGASPMRIICTVLLPEASAGLLRGLTITLVSLIGYS
                     AMAGIVGGGGVGDLAIRYGYYRYETEVMVVTVVALIVLVQVVQMLGDWLAKRADKRDR
                     H"
     gene            complement(36940..37956)
                     /gene="sfbB"
                     /locus_tag="OPY25_000988"
     CDS             complement(36940..37956)
                     /gene="sfbB"
                     /locus_tag="OPY25_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated ABC transporter ATP-binding
                     protein SfbB"
                     /protein_id="HCS0926655.1"
                     /translation="MIEIEKVCVDFTAGRGTPTRAVDDVSLHIAAGEIFGIVGTSGAG
                     KSTLLRTLNALTRPSQGRVNVNGVEISALDGKALRQARQRIGMIFQHFNLMHTRTVAK
                     NVAFSLKAAGWERSKIAPRVAEILTLVGLADKANCFPVQLSGGQKQRVGIARAIANHP
                     DVLLCDEPTSALDLETSATILALLRQINAQLGITIVLITHEMNVIKSICDRVAVMSGG
                     KVVESGEVFDVFAHPQHAFTQQLVSHTLNLTLPERLREHLPGQLLKILFIGDSAEQPV
                     LSEVAIKFGVAVNILHGKIEYIGERALGILVVQLTAPHNPTAVAAAVEHIRQRTAQVE
                     VIRG"
     gene            complement(37993..38823)
                     /locus_tag="OPY25_000989"
     CDS             complement(37993..38823)
                     /locus_tag="OPY25_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCS0926656.1"
                     /translation="MGLRQSLRIAASTLLLACGLQFAHADGSPQTIVFGVAPGPYGDM
                     VKQAIAPTLKEKGYKVVVREFSDYVQPNMALANGSIDANLFQHTLYFDKFTADKGLKL
                     SKLIVVPTAGMGFYSRKINSLDALKKGDIITLSNDPTNLARGLRFLQSLGLITIKHNI
                     DPTKASERDIASNPKGLVFKPLEAAQLPRTLDGVTGALVNGNFAVAAGLDLSSAIKQE
                     HLDENLKNIIAVRSEDADKPFAKDIVEAVKSPAYRAVIDDPKNIYSAFQKPEWMTATP
                     "
     gene            complement(39080..40213)
                     /locus_tag="OPY25_000990"
     CDS             complement(39080..40213)
                     /locus_tag="OPY25_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HCS0926657.1"
                     /translation="MTIKITALAASIGAAVAFMPFATQAEITVLKQDPQAGNPLSRLN
                     FTVGGSIRPQFQNMTGNDGANGYKRNGFDGGTRFRFAADYYLFDDISWISYYELGVNI
                     PAVFDWDNHYAKGTTDTTRRMLYTGFKSATWGTLTFGQQNSIYYDVVGVKTDIWDYDM
                     IGQAPGNGINGDYDGSYRTRKSLKYKKSIGNVDLYASYLFSDDYNANNGLNYKRKGGG
                     SLGADYHLTDDLTWGTAWNYTRAEMRGNGNKTYDQNIVGTALSWTPENWTIAAGGGWY
                     QNFMTTKKVSVNDYFAGDAWGLEYFVGYAFPIGQYAVKAIQPYFMGDRIEYVNGRDYL
                     RTDNGVGITFQLDYGFRVDYEHVFTSSTDNLGDMNLVRLRYDF"
     gene            complement(40399..42813)
                     /locus_tag="OPY25_000991"
     CDS             complement(40399..42813)
                     /locus_tag="OPY25_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0926658.1"
                     /translation="MIARWFWREWRSPSLIIVWLALSLAVACVLALGSISDRMEKGLS
                     QQSREFMAGDRTLQSSREVPKAWLEEARKRGLNVGEQLTFATMTFAGDTPQLASVKAV
                     DSVYPMYGELQTRPGGVKPQPGSVLLAPRLMALLNLKTGDTIDVGDVTLRIAGEVVQE
                     PDSGFNPFQMAPRLMMNMADVAKTGAIQPGSRVMWRYKFGGTPQQLAGYESWLLPQLK
                     PEHRWYGLEQDDGALGKSLERSQQFLLLSALLTLLLAVAAVAVAMSHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIIGQWLMVLGLSAVTGGAIGLLFENILLVLLKPVLPADLPPASL
                     WPWLWALGAMTVISLLVGLRPYRLLLASQPLRVLRRDVVARVWSLKIYLPVACAVVVA
                     LLAGLMGESMLLWAVLAGAVILALLCGLVGWMLLNVLRGMTLTSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIASEQVAPLKAF
                     LAEHQVIPQTFYPIVRARLTEINGNPTEGQQDESLNRELNLTWQDTRPAHNPLVAGHW
                     PPKPGEVSMEEGLAKRLNVKLGDSVTFMGDTQAFSAKVTSLRQVDWESLRPNFFFIFP
                     SGALDGQPQSWLTSFRWENGNGMLTQLNREFPTVSLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTLCGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGLVAG
                     LVAAIGAETALAILQINVFDFPWEPDWRLWVALPFCGALLLSVCGGWLGVRLLKGKAL
                     FRQFSG"
     gene            complement(42810..43496)
                     /locus_tag="OPY25_000992"
     CDS             complement(42810..43496)
                     /locus_tag="OPY25_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0926659.1"
                     /translation="MPAENSVEVHRLRKSVGQGEHELSILTGVELVVKRGETIALIGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGKPLHQMDEEARAQLRAQHVGFVFQSFMLIPT
                     LNALENVELPALLRGENSGQSKAGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDPALAARCDRRLR
                     LVNGQLQEEA"
     gene            43467..44081
                     /gene="tesA"
                     /locus_tag="OPY25_000993"
     CDS             43467..44081
                     /gene="tesA"
                     /locus_tag="OPY25_000993"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HCS0926660.1"
                     /translation="MNFNTVFRWHLPFLFLILLTFRAAAADTLLILGDSLSAGYRMTA
                     SAAWPSLLNDKWQNKTSVVNASISGDTSQQGLARLPALLQQHHPRWVVVELGGNDGLR
                     GFAPAQTEQTLRKIIQTVKAADAQPLLMQIHLPANYGRRYNESFSAIYPKLAKEFDIP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLTPFLS"
     gene            44236..45006
                     /locus_tag="OPY25_000994"
     CDS             44236..45006
                     /locus_tag="OPY25_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCS0926661.1"
                     /translation="MQKSVLITGCSSGIGLDSALELKRQGFQILAGCRKPDDVARMNS
                     MGFTGVLIDLDSPESVDRAADEVIALTDNRLYGIFNNAGYGVYGPLSTISREQMEQQF
                     SSNFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
                     RMELRHTGIKVSLIEPGPIRTRFTDNVNQTQRDKPVENPGIAARFTRDPDAVVAKVRH
                     AFASDKPRLRYPVTLVTWAVMALKRILPGRMLDKILQS"
     gene            45066..45920
                     /gene="cnoX"
                     /locus_tag="OPY25_000995"
     CDS             45066..45920
                     /gene="cnoX"
                     /locus_tag="OPY25_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HCS0926662.1"
                     /translation="MSVQNIVNINESNLQQTLEQSMTTPVLFYFWSERSQHCLQLTPV
                     LESLAAQYHGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYVDALPLLKDAWQLSSQNSEIGLLLAEAQIA
                     LNRSEEAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVADNPQDAAL
                     ATQLALQLHQVGRNEEALELLFSHLRKDLAAAEGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(46006..46785)
                     /gene="fetB"
                     /locus_tag="OPY25_000996"
     CDS             complement(46006..46785)
                     /gene="fetB"
                     /locus_tag="OPY25_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HCS0926663.1"
                     /translation="MNEHNITNTSLALSMLLVVVAMLISHKEKLALEKDILWSVCRAV
                     IQLIIVGYVLKYIFGVNHAALTLLMVLFICFNAAWNAQKRSKYIDKAFLSSFIAITVG
                     AGLTLTVLVLTGSIEFAPMQVIPIAGMVAGNAMVAVGLCYNQLGLRFHSEQQQIQEKL
                     SLGATPKMASAGLIRDSIRASLIPTIDSAKTVGLVSLPGMMSGLIFAGINPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVMPLKKS"
     gene            complement(46772..47449)
                     /gene="fetA"
                     /locus_tag="OPY25_000997"
     CDS             complement(46772..47449)
                     /gene="fetA"
                     /locus_tag="OPY25_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HCS0926664.1"
                     /translation="MTKRSMLLELKQVGYQTATTKIVNNISFTLQRGEFKLITGPSGC
                     GKSTLLKMVASLISPDIGVILFEGRDITTLSPEAYRQQVSYCAQTPALFGDTVYDNLI
                     FPWQIRHQRPQPTAFADDLARFELPETILQKPIAALSGGEKQRIALIRNLQFLPKILL
                     LDEITSALDEHNKRNVNDIIHRYVRDKQVAVLWVTHDKDEIQHADKVITLTPSAGEMQ
                     EARYERA"
     gene            47596..48513
                     /locus_tag="OPY25_000998"
     CDS             47596..48513
                     /locus_tag="OPY25_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HCS0926665.1"
                     /translation="MLILIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINARLLHIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATQMVSEAIAAGDIQALNYFVAQKYTEALQQIGSANNSKVVM
                     MPLDASSLMGAIAGISELVKDSASERKKA"
     gene            48510..48962
                     /locus_tag="OPY25_000999"
     CDS             48510..48962
                     /locus_tag="OPY25_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCS0926666.1"
                     /translation="MIAMILVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     TVWLLPLGWEWQGVLFAALTLLAAWLWWRWLARRVREQKPTDSRLNQRGQQLVGRRFM
                     LDAALVNGRGHMRVGDSSWPVCADEDLRAGTHVEVIAVEGITLRIRAV"
     gene            complement(48963..49379)
                     /gene="cueR"
                     /locus_tag="OPY25_001000"
     CDS             complement(48963..49379)
                     /gene="cueR"
                     /locus_tag="OPY25_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HCS0926667.1"
                     /translation="MNISDVAKKTGLTSKAIRFYEEKGLVTPPLRSENGYRTYTQKHL
                     NELTLLRQARQVGFNLEECGELVNLFNDPRRHSADVKKRTLEKVAEIERHISELQSMR
                     DQLLAMAESCPGDDSADCPIIDNLSGCCHHKAQKLR"
     gene            49489..51990
                     /gene="copA"
                     /locus_tag="OPY25_001001"
     CDS             49489..51990
                     /gene="copA"
                     /locus_tag="OPY25_001001"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HCS0926668.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVELADVTVTEAHVT
                     GTASADALIETIKQAGYGATLSHPKAKPLTESSIPSEALAAVPHELPVATADEESQQL
                     LLSGMSCASCVTRVQHALQSVPGVTQARVNLAERTALVMGSASAADLVQAVEKAGYGA
                     EAIEDDIKRRERQQETAIATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTGDNRSLW
                     LAIGLITLAVMVFAGGHFYRNAWKSLLNGTATMDTLVALGTGVAWLYSMSVNLWPQWF
                     PMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARVVTEDGEKS
                     VPLADVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGTV
                     VQDGSILFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVAIALFS
                     AAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDAD
                     ALQRASTLDTLVFDKTGTLTEGKPQVVAVKTFNGVDEAQALRLAAALEQGSSHPLAHA
                     ILEKAGDDKLPQVNGFRTLRGLGVSGEAEGHQLLLGNQALLNEQHVATDDMTAEITAQ
                     ASQGSTPVLLAIDGKAAALLAVRDPLRSDSIAALERLHNAGYRLVMLTGDNPTTANAI
                     AKEAGIDEVIAGVLPDGKADAIKRLQSQGRQVAMVGDGINDAPALAQADVGIAMGGGS
                     DVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWPF
                     TGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKA"
BASE COUNT        12564 a        14535 c        13095 g        11920 t
ORIGIN      
        1 aacaaatttt ctataacgtc acagaacatc ctacccgcta tccataattc gcatttcgca
       61 agacttttcc gagaaatcag accaggtata atccatattg tttttactta atcagaaatt
      121 tcttttttgt tggtgcgaaa tggatattcc acatatttat tactcttacg caaaatagcc
      181 agtcaacagg gaggtctcat tctttattat tgctccaccg tgtggtgtgt agatctggct
      241 atttcacaat ctttaaggtg tctgacgctt attctaaaac gaaggacgca taacagtctg
      301 aggcatacaa caatgaaacc tgcatctgtt atcattatgg acgaacaccc tattgtaaga
      361 atgtcgatcg aagttttact cggtaaaaat agcaatattc aggttgtcct gaaaacggat
      421 gatagccgaa cagcgataga gtatctgcgc acttatcctg ttgatcttgt cattctggat
      481 attgaattac cgggcaccga cggctttacc ttacttaaac gaatcaaatc tatccaggaa
      541 catacccgga tacttttttt atcgtcgaaa tcagaggctt tttatgccgg aagagcaata
      601 agagcgggcg caaacggatt tgtaagtaaa cgcaaagacc tcaatgatat ttataatgcg
      661 gtaaaaataa ttttatccgg ctattctttt tttccatctg agacgcttaa ctttatcagt
      721 aatacccgtc cccccaaagg cgggcaccat gatatgccac tttctaaccg cgaagttacc
      781 gtgctgcgct atctggccaa tggaatgtct aacaaagaaa ttgccgagca acttttattg
      841 agtaacaaga ctatcagcgc gcataaggcc aatatatttt ctaaacttgg ccttcactct
      901 atcgttgagc ttatcgatta cgccaaatca cacgaattat tgtaaatgta ctcccggcga
      961 attatcgttc gggagccaaa ataacggaca ctaattgtaa ttgatcagga aggtcgcatc
     1021 cgcgttagca agaccgggct gcacgccatc ggctaaggcg atatagttcg catagaattt
     1081 cagggtagca ttgccgttgt tgtcaatatc gacggccttg ctggcctgtt caagtggcaa
     1141 tcgacgttga tcgccatcgc gaatttcaat cgccagtttt tgcgccattg ccgtatcagc
     1201 aagcgccagt aatgccgtgc cgggcgctgg cgtcccggaa aacgttatag acgccgaacc
     1261 tggcgggcag ccttcaagtt ttaggctaaa ggctaccggt tgcgtagcgt ccccggcgac
     1321 gtgaagctgt tttgtcggcc aggtgccgag gttaaccgac ttgttactgt cgcccgcaac
     1381 cacggcgcag gtaaaatcca ccacgttacc gcgcagttca atattcactt cgcccagaga
     1441 tgagttggcc tgactcagcg ggcttaacaa aacacaaccg atagcgatga aaacgcgccg
     1501 aagaatcatt atgcctcctt aatcataatc gactcgtaga tagccgcgcg cagtaaacgg
     1561 cccttccgcc ggtttattcc ccgtcacgct gatcggccag gcgcgaatac ctacgcgagc
     1621 ggcggcgtta tcatcaagat gaaacggaat tttactcgac aaattattgg gtgtgagcgg
     1681 cgtaccgttg ctattagcaa ccacaaagcc taaatccggg ttatcggaca ccatcgcctg
     1741 ccctgaggcc ttttcggctt caagccgcat cgataaatag gcttgcgccg cgacgttggt
     1801 acatttgata gcgatagttt tcgcttgcgg cgtgacgcct tgcggacgat tacccgctcc
     1861 cgcctgacta aataacggcg cgccgatatc gccgaaatca aactccacga cctgtccggc
     1921 attcacttca cagttttgcg gtacttccac tttgccgctg tagctaatgg tatacaccgg
     1981 cgtgctcaac gcgtcgccgg tagaggtcgt cacatagacg gtaaacattg tctggcgggg
     2041 gatcgtcact atattaataa aaggccgtat cacttttaat ttaaaaacca gctttgagtc
     2101 ctgcacgcca aacggctttt gctgcgacac gttagagtcg acgcccatgc gaatatagtt
     2161 acggggcgga taaaatacgc cagcgacact atcggttatg ctcatcgcgc ccagaaggta
     2221 gtcattcaac ttgaggtatt taaaatttcc ttcggtgctt tgtaccggta attctgatac
     2281 atagcttcgg taggtataat tcaccgttgt ccccgccggg cacgtcgcgt ttacgccgca
     2341 ccaatctgat tttttcagca gcgtcaccac ctgtcccggc tgattattgc cgctggtgaa
     2401 aacatctgac aggtcataaa agatatcggt cgccgtcccg tttgaattac ggcaaaccgt
     2461 cgccagcgcg ggatgggtga aaaagagtgc ggtccccgcc agcaatagcg ctgagtatat
     2521 tttcatctct atttttcctt ttatgacgac ggacggatac aggtcgcgct ggctatcgta
     2581 atcgcctgct tcaggctatc ctccgccagg gcgtaagggg cgatacaacg cgcgtttttc
     2641 ccctctcccc actggatgaa cagttcacct tttagcggca agccgctcag ataaatttgt
     2701 ccgtcatcgc cgaccatgct ggtaatgccg ctggcggttt ctcgtactat cgcgccaaac
     2761 ggtaacggac gtccgccaag cctcgcggta atgattgccc ttacgcctat ccgcgtatca
     2821 aaagcagccc gcaccagcgc gccttcagtc ggcaccacgc tgctgacgtt attttcgaca
     2881 tcggtatggt tgtccatcgt gttggtatct aacgcgacgc ggttatagcg atataccgtg
     2941 gcgtagggca ttaccgcata gccccgccag tccgttttca cgccggtctg gttttcgatg
     3001 cgcacgcctt tcgctcccgg cgctttaatc aagacattgg tatcgcccaa cggttggcta
     3061 aacgtaatac catccgtatg accgaccacg ccgccggaaa gttgccagtt atagtcatgc
     3121 tgatcgcgat cgtagttata tcccacgccc agcgtgccat acgtcgcctg ccagctagcg
     3181 ctggcgctgc cgctatgacc attggtactg ctacgcccct gcgtcacgct gtagctcaga
     3241 ttacgtcctt ccagaagcgt gccgcccaca ccggtctgcc agctattgtc gccgtcgcgg
     3301 ttgcggttgg cgttaaacgt ggcataagta cgatcaagaa tagtgtcgcg cgcatagcgc
     3361 cgtccggtca gaacgctaaa cggaacggac atattgaatg ccagaatgcg gtcggcgcct
     3421 gagatcccca ccgactcgct ccacgaccat gacagcgaat aacttatgcc ttgccatcca
     3481 ctggcgtatc ccagttgata ccaggtattg gtatccgccg tattccagta attttgttga
     3541 ctgccggaaa gatacagtga cccgtaattc cccagatttt gcgaaatatt gacctgaaag
     3601 cggccttttt tgctgtagcg gagattgtgg tagctctgcg ccaccggcac tttatggcgg
     3661 cgtccgtcgc tatcgtattc gtagtcgtac ccttccatac tgcggtatgc cacatcatcc
     3721 agggtgtaaa atccgcgcgt ggaatagcgg taacccagca attgaaaatt agtcccgtaa
     3781 ttattcagcg atttggcgta cagaaaacgc aacgattgcc cctgatgggt gctgtcatct
     3841 gccagttggc tacgcgcatg tgtgacatcg accgacacgg ccccccagtc acccaaattt
     3901 tgccccgccc cgaccaccac agcacggtaa cgatcggcaa gttgcgtacc gccgtaagcc
     3961 gtcagccccg caggcaggcc ggcaatcacc gttccctgga aaaagaatag cgaagactgc
     4021 tgactattgc cgctgcgaaa atccccggcc accaggtcat acttcaccct gccctcacgc
     4081 tgcaatagcg gaacggtaga gtaaggcacc gtgtaacgtt gttggctacc gtctttttca
     4141 tctaccgtca cctcaaggtc gccgctggaa gaggtaggat taagatcggt aatcgcaaac
     4201 gcgcccggcg gcacatagct ttggtagata acatacccgt tctgtcgtat cgtcagcttt
     4261 gccgccgtcc gggcgatccc tctgaccgtg ggggcgtagc cctgcaggct atcgggatac
     4321 atattgtcag aagagtacag ccgcgctccg cgaaagccga cgctgtcgaa aacatcgttc
     4381 ccggtatggc tgtcccccat gaccagttcg ctttttagcg gaatgatggc gcgctgtacc
     4441 caggtgccaa tgttgttcca gcgttgcgaa tgatagccgt cccctttcga atagctccag
     4501 gctccgttat tacgcagccg ccaggggcca tagttcaacc cgctcagcag actcaaaaaa
     4561 tagctatcgc tgtctgttcc gcggctaccg gtaaaactgt aattaatgag tgcggcgggt
     4621 atcccttcat cccactcttc cggcgggata tagccacgcg cgctgttgag caatgacgcc
     4681 tgcggcaagc taatgtttaa gcgcatcgac gcgaaatcga acgcgacctc cgcgcccggg
     4741 attttctcag gaaggtgaat acacgtggta tcgacgcctt tatctgagac agggaacacc
     4801 gcggtattca cgcccagccg tttaatcctc tccggtgtaa aacaaggcat caggccgccg
     4861 gatttatcgc cggcgcccac ggcgcccgcc tcaaaacgaa tatcctgcgt cgctacgaat
     4921 tcgtcgttac gccagatatc cacccggtaa ataccgggag gctgatgatt acctttttca
     4981 aagcgagata aatccgccac ggacgcggta tccgccgaca aaaacgcagg gttgaaataa
     5041 ctttcgccgc ggctcgtcag cggacacaga gctgccaaca ccgacagcgc cacgccgctt
     5101 aacggtgata catagccggg aaatcgccct gcaaaccagg ttgtcttctt catcgtgttc
     5161 tcgtgtggct tcacgctctc tgcttaaccg agactggctg ttgtcgccga cgtcaatgcg
     5221 ccgtaatcat tgacggtctg aaatgtcacg ctgccctgcg cgccagtcgg taagggaatt
     5281 tgcatgtcgc tttttggcgc gatcatcacg ttatcaatct ttttcgcacc cacgctgata
     5341 ttgaccagcg tgaggtaata agcagatggg ttggttatct tgagatggtt gccgacacgg
     5401 gaaaatttca gcaaggtcgg cgcgtcttcc ggcgtctgcg gcaaattcgc cggacgcacg
     5461 aacagtttga tgcgcgacag aatcgccagt tgcagaacgt tttttccttc aatatgactt
     5521 ttatcgaccg acgggatggc tttcacgttc atccagaata acgactcccg atcctcgggt
     5581 agcggttgcc cggcgtagat aatacgcagc gtgttttcac ttttgggctc gctgacgaat
     5641 aaaggcggcg taacgataaa cgttttttct ttctgcccag cgttattttc gatccatgaa
     5701 ttgacgaggt aacgttcttg agtatcgcta ttactgattg ccagagaagt ctgtttcgcc
     5761 gccgagggat aaataacacg cgtggcgcct aatgcaatcc cccccgccgc ctgtacgttc
     5821 agcgaagtaa ataacgtgag aagaacaata aatcctaatt ttatactatt cagcatggta
     5881 aaaaatacct tttgcattga gtcacgtcgg caagaaaatt catgggtaaa ccagcgtaaa
     5941 ccacacttct gaatgaattc gtcccggcgt catattttct gaaattgccc gatagcgggc
     6001 ggtaaaatgc aaagtcattt ctgacgttaa aatgggcgcg taatgaagcg gtaacgtgtt
     6061 aggtatgatt tgccgctgct ggtcatcaaa taacgccagg ccgattccgg cattaccgat
     6121 accttcgccg ctggccagaa aaacatgggg atcttccgca ggcgtaacgc cggcaaacgc
     6181 aatgccgaca tgacgccaga cctccgcgct acaggagatt aaccgtaacg aaaatggaac
     6241 gctgacggga gcgaagctgc caggaccggt aaacgcattc gtgcggtact gtcccatcag
     6301 tacgcgcaaa tcctggcttt cagtggcgac agcgcagccg ccattgacca gttgtccgcg
     6361 caggtgaaca cgcccgctct ctaccattac cggctgcgca atgacgggcg acatcaaaac
     6421 aagccccact agcgccgcgc ctttccttat catctgctat gttctctttt atccccgata
     6481 gcctcttccg ttgagacgcc tcccttccct ggcgttccct gacgggatta ttcgtatttc
     6541 atgataaagg tggcgtcggc attagcctgg cctggcgtcg cggcggcggt tgccttatag
     6601 cgtgcggtaa aacgcagcgt attggtgcct tcaaccagcg cctgcttcgc cgagaaggtc
     6661 gcgccgtccg gcttcaacgg tgaggaggtg ttatcaagaa tctcaatccc gacgccggtt
     6721 gcggtagtgc tattgtccgc agaggagacc gccagcaaat tagtgttggt gttatctgcc
     6781 tgaccagaga aagccacggc agcggtggcc gccacttttg gatcgcagtc attcaggacg
     6841 atggagaaag gcacctgcgc ggtcgtatca ccaatcgccg taaagctggc ggtacggtat
     6901 tgacccagcg tcaccgtttg atcggcggat ttagtgctaa cggcacaggc tgcataaacc
     6961 agtttacctt cgaaatgaat agtaccgccg ctcacgctca ccggagtagg atcagccgca
     7021 accgctgcgc cagcgacaaa catcagactc gcaatagtag aggtcattaa tttatgtttc
     7081 atggattttc cttgaattac acacacccgg tttcgatatc ctgtcggctc cgtttgaatt
     7141 attatcgaca tagcatgtca gaaaagttat ctctgcatcc tgtaaagata gatatcgcag
     7201 attaattagt tttctgtttc tcccctgagt atcagacgca gtaattaatc tttgcgaata
     7261 tgacatttcg tcacggtaat aaattaaaca tttcgctaaa taaaaaatag ccgcaaactc
     7321 ttttaatgac ctaagctaat tcttatttgg atataagaag ggtctaatct tattttgtat
     7381 aaaatgtcgc attatgccgc ccgatgctat taacggcgag ggattacggt aaccatagcc
     7441 agggtgatga attgtttctt tttggttaat catggcgcgc ttactggtca cgtctcagta
     7501 tcgtcaacgg acgggggaga cgtcgcgttt gcatcggaaa cacaaacgtt aactgacagc
     7561 gaggcccgct tctgacaaaa tagcgttatc ccctttgact tgaagtaaca gatggaatct
     7621 tctctctgat ggcagcaaag attattgacg gtaaaacgat tgcgcagcag gtgcgatctg
     7681 aggttgctca aaaagttcag gcacgcgtcg cagcgggtct tcgcgctccc ggcctggctg
     7741 tggtgttggt cggcagcaat ccggcctcac agatttatgt cgcaagcaaa cgtaaagcgt
     7801 gcgacgaagt gggattcgtc tcccactcct atgacctgcc agaaaccacc agcgaagccg
     7861 aactgctggc gcttatcgat actctgaatg cagataacac gatcgatggt attctggtgc
     7921 agttgccttt accggcaggt atcgacaacg ttaaagtgct ggagcgtatc gcgccggata
     7981 aagacgtaga cggttttcat ccttataacg tcggtcgtct gtgccagcgt gcgccgcgcc
     8041 tgcgtccctg tacgccccgc ggtattgtga ccctgcttga gcgctacaat attgatacct
     8101 acggcctgaa tgcggtggtc attggcgcgt ctaatatcgt tggacgcccg atgagcatgg
     8161 agctgctgct ggctggctgt acgactaccg ttacgcaccg ctttaccaaa gatctgcgtc
     8221 atcatgtcga gcatgctgat ttgctcattg tcgccgttgg taaaccgggc tttattcccg
     8281 gcgaatggat taaagaaggc gcaattgtga ttgatgtcgg tattaaccgt ctggaaaatg
     8341 gcaaggtcgt tggcgacgtc gtgtttgacg aagccgcggc gcgcgcgtca tacatcacgc
     8401 cagtaccggg cggcgtcggc ccgatgacgg tcgccacgct tatcgaaaac acgctgcagg
     8461 cgtgcattga atatcacgat ccacaaggaa aataacatgg cgacattctc tttaggcaag
     8521 cacccgcacg tcgagctgtg cgatctgctc aagctggaag gctggagcga aagcggcgcg
     8581 caggcgaaaa tcgccattgc cgacgggttg gtgaaggttg atggcgcggt tgaaacgcgt
     8641 aaacgctgca aaattgtcgc cgggcaaacc gttagcttcg aaggccaaag tgtgaacgtc
     8701 gtggcctgat tacgctgtct tttcagataa tcatccactt aatcctctac gttccaactg
     8761 ctagcatggc tatttccctg tgaacgatcg ctatgcctac cgttatcacc cacgccgccg
     8821 ttcctctgtg tcttggcgca ggcttaggcc tgaaagttat ccctcctcgc ctgctgtttg
     8881 ccggtgttgt gctggcgatg ctccccgatg ctgacgtgct ggcctttaaa tttggcgtcg
     8941 cctacggcaa cgtgttcggc catcgcggat ttacccactc tttacttttc gcattcgtcc
     9001 tccccctgtt gtgcgtactc gcgggacgac gatggtttcg agcggggcag gtgcgctgct
     9061 ggctgttttt aaccgtttca ttgttgtcgc acagcctgct ggattcgata accacgggtg
     9121 gtaaaggcgt cggatggctg tggccgtggt cggatgaacg tttctttgca ccctggcagg
     9181 tgattaaagt cgcgccgttt gcgctttcaa gctacatcac gccgtatggg catcaggtga
     9241 ttgtttcgga gctgctatgg gtgtggctac cggggggcgt gctaataggg atattgggct
     9301 ggcacagatg gcgtataggg gacgaaaagc ggactcgcta atgtcggacg gcgctacgct
     9361 tacccgacct gtagatttca tctcaggtag gccggataag acgccctgcg tcttatccgg
     9421 caatacggca attacttacg tcgccaggtg gtgccctgcg ggccatcttc cagaataata
     9481 cccatttcag tgagacgatc gcgcgccgcg tccgccgccg cccagtcttt cgctttacgg
     9541 gcatccagac gctgttgaat caaggcttca atttccgcaa cttcaccgtc atccgcctgc
     9601 gcgccgcttt gcaggaaaac atccggctcc tgctccagca gtcccagcac gccggaaatc
     9661 ttccgcagat gagacgccat cgcattcgcg gcggtcatat cttcgccctt cagacggttg
     9721 acttcacgcg ccatgtcaaa caggacggag taggcttccg gcgtattgaa atcgtcattc
     9781 atcgcctcca cgaaacgcgc ttcaaacgct tcgccgcccg ccggggccgc tgatttatcc
     9841 gttccacgca atgcagtgta taaccgctcc agcgaggcgc gcgcctgctt gaggttctct
     9901 tcgctgtagt tcagttggct acggtaatgc ccggacatca ggaagtagcg cacggtttcc
     9961 gcatcgtagt atttcagcac gtcgcgcacg gtaaagaagt tgcccagcga tttggacatc
    10021 ttctcgcgat ccaccatcac cataccggag tgcatccagt agttgacgta ttcgccgtca
    10081 tgcgcgcagg tagactgggc aatctcgttt tcatggtgcg ggaacatcag atcggaaccg
    10141 ccgccgtgaa tatcaaaatg gttgcccaac tgcttacagt tcatcgccga acattcaatg
    10201 tgccagcccg gacgcccttc gccccacggc gacggccagc tcggctcgcc ctctttcgac
    10261 attttccaca gcacgaagtc catcgggtta cgcttcacgt caacgacatc cacgcgcgcg
    10321 cccgcctgaa gctgctcaag atcctgacgg gaaagctgcc cataagtcgg atcggtcggt
    10381 acatcaaaca tcacatcgcc gttatccgcc acataggcgt gccctttctc gattaaggtg
    10441 cgggtgagct cgataatttc ctgaatatgg tgcgtcgcac gcggctcgct gtccggacgc
    10501 agaatattca gcgcgtcgaa gtcctgatgc atttccgcaa tcattctgtc gaccagcgcg
    10561 acaaaacttt cgccgttttc attggcgcgt ttaataattt tatcgtcgat atcggtaatg
    10621 ttacgcacat acttcagctt ataaccgaga aaacgcaaat agcgcgcgac aacgtcaaaa
    10681 gcgacaaacg tgcgtccgtg gccaatgtgg cagagatcgt aaacggtgat accacacacg
    10741 tacatgccga cttccccggc atgaatgggt ttgaattcct ctttttggcg cgtcagtgta
    10801 ttaaaaattt ttaacatcga agattccgta tagacgtgtg tgggtaatta ggtgtgtata
    10861 atactcataa ttcaaccttg aagcagcaca ctttgcaagg tgatcgcagc ttacgattat
    10921 gctataacaa gcccctatat gtgccccatt gcgggctaaa gcaccactct cttggaacag
    10981 gatgcaaaaa tggttacttt ccacactaat cacggcgata tcgtaatcaa aacctttgat
    11041 gataaagcgc ctgaaacagt taaaaacttc ctggactact gccgcgaagg tttttacaac
    11101 aacaccattt tccaccgtgt gattaacggt tttatgattc agggcggcgg ctttgagccg
    11161 ggcatgaaac agaaagccac caaagaggcg atcaaaaacg aagccaacaa tggtctgaaa
    11221 aatacccgtg gtacgctggc gatggcgcgt actcaggcac cacattcggc taccgcgcaa
    11281 ttcttcatca acgtggcaga caacgacttc ctgaacttct ccggcgaaag tctgcagggc
    11341 tggggctact gcgtctttgc ggaagtcgta gaaggtatgg acgtggtaga taaaatcaaa
    11401 ggcgtcgcca ctggccgtag cggtatgcac caggacgtac caaaagaaga cgtcatcatt
    11461 gaaaacgtga ccgtcagcga gtaatcgtgg cgacactgtt tattgcagac ttgcatctgc
    11521 aaacggaaga accggcgatc gtcgccggtt ttctgcgttt tttagccgta gaagcccgtc
    11581 aggccgacgc gctgtatatt cttggcgatc tcttcgaggc ttggattggc gacgacgacc
    11641 ccaacccgct acatcgtgaa atggccgttg ccattaaatc gctggttgat tccggcgtcc
    11701 cttgcttctt tattcatggt aatcgcgact tcctgattgg caaacgcttt gcccgcgaaa
    11761 gcggcatgac gctactaccg caggaaaaag tgctcgacct gtatggccgc aatgtgttga
    11821 ttatgcacgg cgatacgctc tgtaccgatg atgccggata tcaggcgttt cgcgccaaag
    11881 tccataatcc gtgggttcaa cggccgttcc ttaccctgcc gctgtttatc cgccgccgta
    11941 tcgccgccag aatgcgcgcc ggcagtaaag ccgccaacag cagcaaatcg ctggatatta
    12001 tggacgtcaa tgcgcagacc gtcgtcgccg aaatggaaaa acaccgcgta cagtggctga
    12061 ttcacggtca cacccaccgc ccggcggtgc atgaactttc cgccaacggc cagcccgcgt
    12121 tccgcgtggt gttaggcgca tggcatcatg aaggttcaat ggtaaaagtc acgccggata
    12181 acgtggagtt aatcgccttc cccctgtaaa tgttcgtcga atcgtccgtt acggcgcaca
    12241 cgcaaccgtt ttccttgcct gattatcatg ctattctctg acacctcaaa agcagcgtgt
    12301 cccgcaccac aggagtttta agacgcatgt cttcccgcaa taatccggcg cgtgtcgcca
    12361 tcgtgatggg gtccaaaagc gactgggcta ccatgcaatt cgccgccgaa atttttgaaa
    12421 ttctggatgt cccgcaccat gtagaagtgg tttccgccca tcgcaccccc gataaactgt
    12481 tcagcttcgc cgaaacggcg gaagagaacg gatatcaagt gattattgcc ggcgcgggcg
    12541 gcgcggcaca cctgccggga atgattgcgg caaaaacgct ggtcccggta ctcggcgtgc
    12601 cggtacaaag cgctgcgctc agcggcgtgg atagcctcta ctccatcgtg cagatgccgc
    12661 gcggcattcc ggtgggtacg ctggcgatcg gtaaagccgg ggcggcgaac gccgcactgc
    12721 tggcagcgca aattttggct acgcatgata gcgcgctgca tcggcgcatc gccgactggc
    12781 gcaaagcaca aaccgatgag gttctggaaa atcccgatcc gcgggggacg ctatgaagca
    12841 agtttgcgtt ctcggcaacg ggcaactggg ccgaatgctg cgccaggcgg gcgaaccgct
    12901 gggtatcgcc gtctggccgg ttggtctgga tgcagagcct accgccgtgc cggtacagca
    12961 gagcgtcatt accgcagaga ttgagcgctg gccggaaacc gcgcttaccc gcgagctggc
    13021 gcgccacccg gccttcgtca atcgcgatgt atttccgatc atcgccgacc gtctgacaca
    13081 aaaacagctt ttcgataaac tgggactcgc gaccgcgccg tggcagctgc tgtccagcgc
    13141 cgacgagtgg tccggcatct ttgaccgtct gggcgaactg gcgattatta agcgtcgcgt
    13201 tggcggctac gacggtcgcg ggcagtggcg tctacgcgcg gacgaaaccg ggcaactgcc
    13261 ggatgactgc tatggcgaat gtattgttga gcgcggtatc catttttccg gcgaagtgtc
    13321 gttagtcggc gcgcgcgctc atgacggcag taccgtgttt tacccgctaa cgcacaattt
    13381 gcatcaggac ggcatcttgc ggaccagcgt cgcgttccca caggcgaacg ccgaacagca
    13441 ggagcaggcg gaatcgatgc tgtcagcaat tatgcaggcg ttgaactacg tcggcgtaat
    13501 ggcgatggaa tgttttatca cgccggaagg cctgttaatc aatgaactgg cgccgcgcgt
    13561 gcataacagc ggacactgga cgcaaaatgg cgccagcatc agtcagtttg aattgcattt
    13621 gcgcgcgatt accggcttgc cgttgcccgc gccggtgatt aacgccccgt cggtgatgat
    13681 caatctgatc ggcagcgagc tgaattacga ctggctgaag ctgccgctgg tacatctgca
    13741 ctggtatgat aaagcggtac gtccggggcg aaaagtcggc catctgaatc tgaccgacag
    13801 cgatacgtca cgtcttagcg ccaccctgga agcgctctct ccgctcctgc cgggcgaata
    13861 cgccagcggc attatctggg cgcaaagtaa gcttaaataa acagcgtggg cggcgcattc
    13921 tctgtcgccg cccgtcgcga tcacagacag atgcaggttc ccgccctgcc cgccagggta
    13981 tcgtcaatac gcgacagcgc gccaatccat gccggctttc cgcaccgctt cacatacccg
    14041 cttaccgcgg tcaccttcgg tcccatcgcg ccatcggctt tggcaaacgg cgccagctca
    14101 tcgggcgaag cctgacgaat agcgcgctgc tgcggcgttc cccaatgttc atacaccgca
    14161 tccgcatccg tcaaaatgat cagaccatcg gccgctatct gctccgccag caatgccgcc
    14221 gccaggtctt tatctatcac cgcctcgacc ccttcgccct cgccagcaac aggtaccccg
    14281 ccaccgccgc tgcaaatcac cacatggccc tcttttagca ataactcaat agcggtgctt
    14341 tcgataatct gacgcggcgc cggggaagcg acgacacggc gcagatattt tccatcacgt
    14401 ttcatatgcc agccataagt cgcttccagc gccatttgct cttctggcga ataaacggga
    14461 ccgataaact tttccggttc aagaaaagca ggatcgtccg ccgatacctt tattcgcgtt
    14521 aataccgcag tcaccggcgg catatcgggt tcaagcgcca gacgctgcgc cagcatatag
    14581 ccgatcattc cctgactttc cgccaccagc acatccagcg gataaggctc aacggctttc
    14641 caggcaaggt tctgtaaagc caacaggccg acctgggggc cgttgccatg tactatcgcc
    14701 agccgatacg agcgggcaag tcgtgccagc gcaggcaccg cgtcggcaat attgcgatat
    14761 tgattctctg ccgttagcgc ttctccgcgc tgcaataatg cgttgccgcc aagagcaact
    14821 accaacgttt tcattcccta tccttttact atttgttgtc caagccagaa ccccagcagc
    14881 gtatccgcgc cagaggtgtg ccccagcgcc agcagtccgt caatcgccgt ttctgtgcga
    14941 gcatctcgtc gcagcgcatg aataaagtgg agtaaaggcg acgcgaaata ccccatagcc
    15001 gcatagcgta aatagctgac gctcacgagc gtcgtcgccc gatcaaggct gccggattgg
    15061 gcaaaaaaat tacgcccggc gcgttcatct atggcgccaa aataccaggc cgccagcaac
    15121 attcccgtca gcgtgtcctc atgactgggc gttaagcccg gccctttacc cagccatagc
    15181 cgccagtcag tcgcagcacc tgcaagcgct gactgaaagc agtgacaaaa ctggcgaagt
    15241 tccggacata gaggctgagc tgcggcgacg gttaacggcc caaacagtcc cgtctcctca
    15301 ctacgctgca tgtacgtcgc gttaaggcgc ggcgacgcaa gatagcgtgg aacccgcagc
    15361 gaacagcgcc tctccggctc gcataaaaga aactcgccaa tctgaatacc ggcagcggtt
    15421 aactgcggtt tttcgccatc ggtgagcaca tcacgcaagg cgtcaaaatc gccgccgcgc
    15481 agtatccacc ctcctggact gaagccgctc ccccgacggt gaagcgttaa taactcaccg
    15541 cttttcgcca caaaattaat agagcgacgc catacccctg acatctgcca gggttgccga
    15601 taatccgccg attgtcggct tgccataaga ggatggatac gtttcatgag acgctctctt
    15661 aacttacgcc catgctttcc gccagcgctt ccagcgcctg ctcgaaacag gccagcggcg
    15721 cacggacggt tcccgcgcca atctgaccaa ttcccgcctc tttatgcgcg atacccgtgt
    15781 taatcagcgg cgtaattccg gtctcgacca cgcggcggat atccagtccc agacaggccc
    15841 cctgaaaatc ccagccgggg atttgtagct gcatgttgcg ttcgagataa atttcagcca
    15901 tctcttcaga aacagatttc gccgcttcca ttcccccggc accgacaaaa cgcgttacgc
    15961 caggcgcggc aatcatcgct gcgccgccaa taccaaacgt ttcagtaatg gcgctgtcgc
    16021 ccatgtccgg gttggcctga tcctgcgaaa aaccggtaaa aaatagcccc tgcggcgtat
    16081 taacaggcgc ggtgaaccaa cggtcgccca gaccgctaac ccgaatgcca aacatatcgc
    16141 cattgcgggt catcgccgtc acaatactgc cggcgcgaat ctgcgcgccc gcgtccatgg
    16201 cggctttaca gtaggccatc gccagattaa ggaagaattg atcggtgacg ctcagaaaat
    16261 ccatcacttc cgctatctgc tgcttatcgt gttgcagacg ggcgatatgc ggcgccaacg
    16321 tgcgcatcag caatgcggaa gaggcgatat tgcgctggtg gaattcatct cccatcgtaa
    16381 tgccctgcgc catcatcgcg gtcaggtcaa gcccccgctc cagacgaccc agcgccgcgc
    16441 ttaataccgg catcagcaca tcgcgcatcc agcgcaaacg ttgctgaaca tcttcgccat
    16501 aggcgccgaa acgcatcact ttgccgatcc cttcgttgag attgcagtac gcgcgattgc
    16561 cgtcggtgat attttccacg accagcatcg gcatactggc tgacgtaata ccgcccatcg
    16621 gccccacggc gttaacgtga tggcagggaa taaagttgac ctttccctgc tctaacagcg
    16681 cgagcgcgct catttcatct ttggcccatc cttcaaacag gcatgcgccg atacaggccc
    16741 ctttcatcgg gccggtcatc tcttgccagc gcatcggcgg cccggcatga agaagcgttt
    16801 tcccctgatt gagtacgcta attaatgaag aagctggctt cacatccagc cagtgcggac
    16861 gtgcgcgacg aatttgttcg atgactgcag cgttggcttg cgccactgat gtaaatatgg
    16921 gaacccctta ttgcaaacgt tctaacagac gagccagttt tttattaccg ccagcgacag
    16981 gcgcccactg gtagtgcacc acgggcatac cggcagcctg taaatccagc gcgaagctac
    17041 gtaacccggc attaatcacc gctactgctt ccagtaaccg gggagctgat ggatgagtag
    17101 aagagagagt gggtcgaatc agttccgcgg ccaacagagt ggcttcggga agagaatcca
    17161 ctaccgtgat gccggcatct tcgagcgcgg cgatttgttg cgagcggcac tgaggatcgc
    17221 gttccgttcc ggtgacggtt gcgatggcga acagcggctg gtcgctggcg cgtgcggcgc
    17281 atgccttctg ccaggcctga atcagcgatg cggcgggatc ggcggtcgcg ccaaaaccaa
    17341 taacgacgtc cactaataac acgcgtacct gcggttgtgc gccaagcccg gcgataagct
    17401 gattacgtaa cgccgggtca atcatcggat gtggtcgccc aacggtataa aagtcatcgc
    17461 ccagatcgat aatctggtgg ccgtcagcgt caagcatcat gccatggtga tgttccgtat
    17521 ccgtcgcgac gcccagatag ccggccagca gtcccgccgc ttccgccgcc agcgttccgc
    17581 cggtatagag accacgaatc acgccgcctg ttgaaaccat ttctttacgc tgcgacgtca
    17641 cgcgagacaa taaacatgcc agtcgggcag cttcatccag cgtcgaggca aaccagacgt
    17701 tttcctcacg cgcaacggga gaggaaaacc ctaagaacag cgctacaacg ggtttcccgg
    17761 tggctttcat cgccgcgata atatgctgac gaaccgcatc agcaggcggt ttggagacaa
    17821 aggccagcac ctggctcttt tcatccgcgc tgagtatgtc cagtgccgtt agcgcgctga
    17881 tcccgccgac ctcggcgctc aaatcgcgtc cgccaagccc gatggcatgg gtaatccctt
    17941 cccccgccag cgcaatctgt gaacagagct cctgaatacc ggtgccggaa gcgccaatca
    18001 ccccgatgtt gccctctggc atgacgttag cgaaagccag cggcgtattg gcgatcatag
    18061 cggtgccgca atctggcccc atgaccagca gtcccttatc acgcgcccgg cgttttagtc
    18121 tgatttcgtc gtccagcgtg acattatcgg agaagatcat cacgttcaac gaacgagcca
    18181 gcgcctgctc cgccagttcc gccgcatatt cgccggccac cgataccagc gccagattcg
    18241 cctctggcag tttctgacag gcgctttccc agcgtctgac ctggattaac gactggctgc
    18301 cgctgcttcc ctgcgccaac tgctgcaatg cttcttcgag ctgtcgcaca atcacctgcg
    18361 taatgccgtc atctaccgct tcggtacgaa tcgccacgca aatgtcattg ggcgtagcgc
    18421 catgaaaatc gtcatgccag aaaccggtag tttccagcag cgacttattc gcaggcgtac
    18481 ccatcattac cgatacatca tcaacatttt cggactcact cagctttcga gaaataatca
    18541 ttaagctgac agagtcctga aaacaccctt ttttaataaa ggcgtggatc ataacaactc
    18601 cttaataatt gcacccattg caattgcacg agcagtgtta atgtgcgctt cacggtatat
    18661 atccgggagg gtaaatagag tgattaacgt cacatcaaat ttattaacaa aagaattcaa
    18721 acaacggcta aaggattagt tatgattttc taaaaaagct ttttatttaa gcaaaaagat
    18781 aaaagccgcc tgattatcaa ataaattcta attatatttt tttgcctgtc tggatcacat
    18841 aatcatttta ttttcccggt atgttaatcg cagtcatgct tcacaccgtc gttaaaaagg
    18901 aagacagatg aaaatcagtc gggaaacact ccatcagctt atcgaaaata agctttataa
    18961 agccggacta aaacgtgagc acgccgccat cgtcgccgac gtactggttt atgcagatgc
    19021 cagaggtatt cactcacatg gcgccgtacg cgttgaatat tatgccgaac gaatttcaaa
    19081 aggcggcacc aaccgggagc cgacgttccg cattgagaat accggtccct gtacggcgat
    19141 actgcatgcc gataatgctg ccggacaggt cgcagccaaa atgggaatgg agcatgctat
    19201 tgaaatagcc aaaaaaaatg gcgtcgcggt tgtcggcatt agcagaatgg gccatagcgg
    19261 cgccatctct tatttcgtcc gccaggccgc tcgcgaaggc ctgattggtc tgtctatctg
    19321 tcagtccgat cctatggtcg tgccgtttgg cggggcggat atttactatg gcactaatcc
    19381 gctggccttt gccgcgccga gcgaaggcga tgacatcatt acctttgata tggccaccac
    19441 cgtgcaggcc tggggaaaag tcctcgatgc acggtctcgc aatgagtcca ttccggagag
    19501 ttgggccgtc gataaaaacg gcgcgccgac acatgatcct tttgccgtca atgcgttatt
    19561 acccgccgca ggcccgaaag gttacggcct gatgatgatg atcgatattt tgtccggcat
    19621 tctgctgggg ctgccgtttg gtcgccaggt cagttcgatg tatgaagatt tacacgccgg
    19681 acgcaattta ggacaacttc atctggtcat taatccggcg ttcttttctt cctgtgaatt
    19741 attccgcaaa catattagtc agactatgca ggaactcaat tccgtgaagc ccgctcccgg
    19801 ttttaaacag gtttattatc ctggacagga tcaggatatt aaacagaaaa atgccgatat
    19861 gaatggtatc gatattgttg atgatattta tcaatatctg atttccgatg ccctctatct
    19921 caagtcatac gaaacaaaaa atccctttgc ccaataatta ttgaaacagg aattttctat
    19981 gataaagcat tttcgccacg cgatagaaga aacattgccc tggctctctt ccattggagc
    20041 cgatcctacg ggtggaatga cgcgtttact ttattcgcct gagtggctgg aaacacagca
    20101 gcaatttaaa aagcgaatgg cagaaagcgg tctggaaaca cgctttgatg acgtcggaaa
    20161 tttatatggc cgcctttgcg gcacacaatt tccggagcag gtgattttaa gcggttcgca
    20221 tattgatacg gtcgtcaacg gcggcaatct ggacggacaa ttcggcgcgc ttgccgcctg
    20281 gctggcgctc gactggctaa aagcgaccta cggcgcgccg ctgcgcaccg tcgaagtagt
    20341 gtcaatggca gaggaagaag gcagccgttt cccttacgtt ttttggggca gcaagaacat
    20401 ttttggcctg gcgaatcctg aagaggtacg ctatatccag gacgccaaag gcacaggcgt
    20461 tgtcgacgct atgcaggcgt gcggatttac ccttcccgcc gcgccgctcg ctgcgcgaac
    20521 cgatatccgc gcctttgttg aattgcatat tgagcaaggc tgcgttctgg agagcaacgg
    20581 acagtcgatt ggcgtcgtca acgccatcgt cgggcaacgt cgctacacgg tgacgctcaa
    20641 cggcgagtcc aaccatgcag gcacaacgcc aatgggctat cgtcgcgata cggtgcatgc
    20701 cttcagtcgt atttgcagtc agtccattga aaaagccaaa cagcatggcg atcccctggt
    20761 attaacgttc ggcaaagttg agccgcagcc gaatacggtc aatgttgtcc ctggaaaaac
    20821 cacatttaca atcgattgcc ggcatacgga cgccgcggta cttcgcgaat ttaccgaaca
    20881 gttggaaaac aatatgcgcg ccatctgcga tgaaatggat atcagcatcg atatcgattt
    20941 gtggatggac gaagcgccgg tgccgatgaa cgccgaactg gtcgcggccc tcaccaggct
    21001 gtgtgaaacc gaacaactga actatcgcat aatgcatagc ggcgcaggtc atgacgcgca
    21061 aattttcgcg ccgcgcgtcc ctacctgtat gattttcgtc cccagcatta atggtatcag
    21121 ccataacccg gcggaacgta ccaacattaa tgaccttgct gaaggggtca aaactctggc
    21181 attaatgctt catcaacttg cctggcaaaa ataaggagcc atcaatggga tatctgaata
    21241 acgtcacggg ttaccgcgat gatttactgg cgaaccgcgc cattgtgaaa cacggtaact
    21301 atgcgctctt aacgccggac ggtctggtga aaaatattat tcccggcttt gaaaactgtg
    21361 acgtcaccat cctttcgacg ccgaagctgg gtgcttcttt cgtcgattac ctggtcacct
    21421 tacatcagaa tggcggcaac cagcagggct ttggcggcga ggggattgaa acttttctct
    21481 atgtcattgc gggaaatatt gaagctaaag cagaaggaaa aacattctct ttaactcagg
    21541 gcggctacct ctattgtcca ccgggggaga tgatgacctt tagtaacgct caaacggaag
    21601 acagccagct atttttatat aaacgccgct atactcctgt cgaggggcat gccccgtggt
    21661 tggtttccgg caatgccagc cagctggagc gtattcatta tgaaggcatg gaagatgtta
    21721 ttctgctgga tttcctgcct aaagagctgg gcttcgatat gaatatgcat attctgtcgt
    21781 tcgaaccggg cgccagccac ggctatattg aaacccacgt ccaggaacat ggcgcttata
    21841 tcctttccgg ccagggggtt tataacctcg acaacaactg ggtgccggtg aaaaaaggcg
    21901 actacatctt catgggcgct tattccctgc aggccggata cggtgtaggt cgtggcgaag
    21961 cattcagcta catctactcc aaagactgta accgcgacgt tatgatttaa cggcgggcag
    22021 ccctcctgat tatttttatt tagctatgtt ggattttgcc acggtgagaa ccgtggattt
    22081 ttttatactt aacgagtccc gatgtcctgg ccaagtttga tgacgcgggc aatattacag
    22141 gcgctgtggt agagattttg ttcaccgttc gccagaacct ccggcaaagg cgccagccgc
    22201 ggcaaaatac tgaatactgc atcaataccg tgacgatgga ccacttccac gccgtcgccc
    22261 aatacgccgg caatgccgat aaccgggaca tgatgccgtt tcgccactga tgcgacgcct
    22321 atcggcgctt ttcctcccgc cgtttgcgag tcgattcgcc cttctccggt aatcaccagc
    22381 gaggcctctt ttaccgcctc ctccagcttc accgcctgca taacaatctc aataccgggc
    22441 ttcatttccg cttccaggaa gacgatagcg gcaatcccca ttcctccggc cgctccaccg
    22501 cccggtattt gagacatgtc gcgtccggtc agggcatgta aaatacgggc ataattacgc
    22561 aatccatttt ccagcgtctc gaccatttca ggcgtcgccc ctttctgcgg accgaatacc
    22621 gccgccgcgc cgcgtggccc caccaacggg ttatcaacat cacaggcgac ctcaatacga
    22681 cactctgaaa ttcgcggatc gcgcccctgc aggtcaatgc tcgccaggcg cgataaattg
    22741 cccccttcgg cgccaagcgg cgttccctgc gcgtccagaa aacgcacacc gagcgcctgc
    22801 gctactccca ttccgccatc caccgtggcg ctgccgccga tacccagaat aatatggcga
    22861 attcccgcgt ccagggcgtg acgaatcaat tcgcctgtgc cgaaactgga tgcccgcagc
    22921 ggattacgcg cctcgggcgc caccagcatc aatccgctcg ccgccgccat ttcaataatc
    22981 gccgttttgc cgtcgccggt caggccataa aatccgttta ctttttcccc catcggcccg
    23041 ctaacgtcca cagaaacccg tttcccgccg gtcgcagcca ccatcgcatc cacggttcct
    23101 tctccaccat cggcgatcgg taaacaaaca tagcgcgcat ccggaaatac ggttgaaaat
    23161 cccgctttaa tagcctgaca gcatttatca gcgcttaagc tctctttaaa tgaatctggc
    23221 gcaattacaa tcttcattat gtctccttgt tttctcacgt tatttaatgc gttcccacgg
    23281 aataagattt tccataagca ctgccagtag gattcccacc agtaatccgt tactaagcag
    23341 aggacgaatc atcagtggaa gatcctgtaa atagaccgga ggaagcccca tcaaaaaaat
    23401 gccgacaaaa agcggtaacg ccaggcgata aatattccgc gcggtaaacg taatttgctg
    23461 gctaaaaacc aaaccggaat aaagtaaagg taaataagag accagcataa cggcgctgct
    23521 gatcgccagt ggaatagcgc aaaataagcg ggttaacggc gttataatgg caaccagcag
    23581 acacagcgcg ctaccgcaga taaaggattt gcgagaactg tcgccggttt gcgttaataa
    23641 accaatggaa gatacaaaag gcgaaaaagg cacgaccgca aaaggcaccg tcactaacgt
    23701 catcagtccg gaaatcataa agcttcggcg ataacgagaa ctgcccgacc cttgatgcgg
    23761 ataaaagata tcggtaccgc ggatagcgcc gtaagtgttg ctgatgttga ctaaccccgt
    23821 catcaccgcc gtcacaataa tacccggcat cagcgtgccg tggctgccca gcggaaacca
    23881 tcgccagctt aattcacccg gcggtaagtg tgacgaagga aagcataacc gccatagccc
    23941 ccacccgacc acggtcccta ccagtaacgc gtaacgggag atacgctgct gcaagaaaat
    24001 aatcatcgcg aggataaaac acatcaccgc gaccgccagc ccaaaggggg ccaatttgat
    24061 tctggcgctg gtatcggcaa tgccaaaagg cagccccagc atgcctttaa aaaatattga
    24121 ggtcagctgc gcgcccaaaa gcagcatgaa aaaaaccatt accgccggcg taaacaggcg
    24181 agccagacgg tgtcctaagc cgctaatgcc gataaatatc gtcaccatcg cggagatcgc
    24241 gatcccgacc gacaggctgg aggcgatatc gttcagcggc gtgccgcgag acgcctcgcc
    24301 aagcgtaatc gtaagtatag cgccccacca caaccctgtc ggcccttcca taatggcgcg
    24361 gcgatggccg caaaatgcct gaaccaggca ggccaacgcg gtggtcagaa aagcgtattg
    24421 tgtgagcatt aacaggttat cagcgggaag atgaaaagcg gacagcaagg tagggggaac
    24481 cacaaccgtg ttacagaaaa taaagaaaaa ccactgaaag ccggacaata cactttcgcg
    24541 gttaataaca gggaacatat ccacacctta aaatagagaa tgcccgtcgt gacgacgggc
    24601 attaaatcac accggattac tgctgatgtt taaggataaa ctgacctttt ggcggcacag
    24661 ggaagccatg ctcgatgtca taaataacat cgccgcgcaa aatcgttttg gtaatacgcg
    24721 cgccaatagt acggccaaca tacggactga ctttatggcg atattccaga tcttcatttt
    24781 tcagaacata gctgctgtca ggctgaataa agaccaggtc agcatctttg ccgggggcaa
    24841 tacgtccttt atgtttcaga ccaaaaatat cggcggcgtt ggtcgccatt aatttgccaa
    24901 acatcggcaa cgacataccg cgtttttgca ccgcttcatc aaacatgacg tccatgcagt
    24961 tttgcagtcc ggcaattcca ccccatgctt gcatgatatt gcctgctttc atttccggag
    25021 gacatggaga gtggtcggat accaggcagt cgatttcgcc gttaaacagt ttttcccaca
    25081 tccctttctg gttttcctgg tcgcgaattg gcggagaaca ttttgccagg gtgccaatct
    25141 cttcgaactg atcggtatcg aggacaaaat agtgcgggca cgattcacag gtgacatcct
    25201 ggccttcctg acgcgcacgc gttacttcct ctaccccctc cgggctgctg atatgacaaa
    25261 cgtgcagacg gcaacctgcc gctttcgcca gatacagcac gcgacgaatg gcttccactt
    25321 cagtaaatac cggacgtgag gcgacataat catgcgccgt tacgcgacct tcgcgtttag
    25381 cttcttcgcc cagctcatcg caaatcagag cattttcgca atgtaccagt accgtctggt
    25441 ccatctctcc cagtttttgc gcgcctttgt aaaactgcca gtcattaacg tcgcgaaaat
    25501 cattatcgat gccacgatcg ccgcaggtgg cgacaaagca cttgaagccg acaacgccca
    25561 cttcgtccag ctcatgcagc cgatccaggt tataagagac caaaccgccc aactgcgcgg
    25621 cgtcgatggt caatttacct tttgccgcgt caaacttgag ttcaatcgtc tcacgatcga
    25681 ccgtcgccgg cagctgattg agcggcatct caatcatcgt ggtaataccg cctttcgccg
    25741 ccgcgcgcgt accggtttca tagccttccc agtgggtacg gcccggttca gaaatgtggg
    25801 tatgcgcgtc aaccatgccc ggcgaaacga tcaatcccgt cgcatccagc acgtttttcg
    25861 cttcccccag gttctcgcca atcgcggcga tttttccgcc ctggacggcg atatcgataa
    25921 ctctcgcttc gttttctaag atgacagtac cgttcttaat aattaaatca aaagacataa
    25981 caaactcctt gtatggatac agatagtttt taaatagtgc acacttcatt aaatacgctt
    26041 aatatttttt caatagttaa cctgcgactt tttgctctcc tgtattttca aaacccgtgc
    26101 gtttcttcag tagcgcataa gcaacgaacg caactattac gcctacaaac caggacacgc
    26161 gggataaagg ctccataaat ggtataaact tgccgcctaa tgacagaatg actgcgacca
    26221 gggtgactga aaatgcagtc aggttaaatc cattatcata atatttgtaa tcaccgctgg
    26281 cggtgtatag ctcatcaaga ttaatttttc cacgcattac cacaaaataa tgagctaaca
    26341 ttacgccgat taccgggcca agcataccgc cgataatatc gaggaacaga taaatactgt
    26401 cctgattctc cattaatttc catggacaaa tcagtagact gataatactg gcaatcatta
    26461 cgccattttt atagttaagc tttgtcgggg taagcgccgc aatttgatac cccgcaggca
    26521 taatattacc ggtggcgttg gttgaaattg tcgtcatcag aatcaccagc actgcaaaga
    26581 atgaagcaaa caggctgtcc cagcgctgca caatatccag cacgttccag gtatccatac
    26641 cataatgaat actggctccg gcaataatgc acacgctggc tacggcgaat aatatatacg
    26701 ctacgataag ccccaatgtt tgtcccaatg cctgagcgcg aaatgaatgc gcgttttgcg
    26761 tgaaatcgga cgcgctcacc gctggcgcag cccagacggc gactacggcg ttaatcacca
    26821 ccaggaacag aaagccgctg tgctctgctt tttgcacgcc tgaaggcaga tagtccaaaa
    26881 tcgggccaat gccgaccagc gatattgccc aaatagccat gccgccaaag acaatataaa
    26941 tacatggatt gaggatagcg gtaaatttat ttaatacttt accaccgcca aaaccgatgc
    27001 caacgttaat gatccaaaaa attagaaaag taattagccc tggcagtgaa aaacccagca
    27061 gcttgaaatc tccgcctaat gtctaaaatc ctggccagat cttcccaatt aaaataagaa
    27121 atgccagcga tcccgcgtaa cactgtaagc cgaaccacat aattgccgcg attccccctc
    27181 gtaataatcc agggaatagc gcgccgcgga cgccgtaaga acctcgcaat atcatagcaa
    27241 aaggaacgcc atatttgctg cctgccgcgc cattcattac catcgccgcc gcaataaata
    27301 atgcgctgat aataatggcc aacatgatat taaatgttga tagccccagt ataaaaaaac
    27361 cgccgaccat aacgtaattt ggcacgttat gtacagatcc catccataag gtgaaatagt
    27421 taaatgcttt ccagtttcgt tgggtttctg ttttaggtaa taagtcttcg ctataaccgc
    27481 gttgctgata tagctctctt tgatgttcca taaatccctc ttttcacgca tcggataacg
    27541 ttgttatggg tttagctatg aggaacaaat aaatataaaa taaagaaata gtagatataa
    27601 ttatttttaa gctgaagcaa tacgttgcgt tgctttcttt ttatataatg tgacagcagc
    27661 aaagatcagc gttccggtaa ccactaaaca tgctgaaatc acaaaactga tctccttcga
    27721 ccccgttaca tccgaaataa atccggtcaa cgttggggcg acaaccgctg aactcatgcc
    27781 aaagaaatta aaaaggctga aagctcttcc cagacttttt gccgaagcct gttcagatac
    27841 aaaggagatc aggatcgggt ctactgccat tttccctagc aagccgtata gcgtcaggct
    27901 gaccatcagc atcgtggtat tcggggacaa aaccgtaaac gccaacattg ccgccgccac
    27961 aatttccaga ccgagaataa ccttaacttt actgttacgg aatttatctg acagatggct
    28021 aaaaaataac gcccccggta cgccaaccac cgccaccaga gctgatgcca gcccgatagc
    28081 tccgccatca aatcctcttt cagtctggag ataagaaggc agccaggtca ctatcaaata
    28141 ataaccgtag caggtacaga aatagaggaa gtaaacgcta cacaataaac cagagaataa
    28201 aggcgcgcgt ttctcatctt ccgtaacggt ttgggtttgc ttttccgctt gcgcagagtc
    28261 gcttttggct ttaccacgaa tgaccagcgt aaagacgcac agcataatta ctaatatcgc
    28321 ggccacgata tacagtacat tttgccaggc catgctcatg ttttttacta atacgctgga
    28381 accgattaag ccaatcccca tccctatagc cgacccgctg ttgataatcg cgttggctaa
    28441 tgcccgacgg gcctgcggca cgtttgccga agagagtgaa taagccgaac taaagaaaga
    28501 agcgcatcct ccgcctgcca ttagcgaccc tgtatagatc atggccaggc cattggcttt
    28561 cgcgatacag agtgtaccaa taataaaaag cgtaaatccg gccatcagca tgattttttg
    28621 accgaattta tcgaccaata ttccgcaagg gatttgcata ctgcagtaag caaaaaagta
    28681 aaaacttgca atggcgccta tttctgcatt acttacattg tctaaagatg cctgaatttc
    28741 tggataaatt ggcgtaagca cggtgcgata gatccaaatc gctacccagc ccagactcat
    28801 tacgacaaca atttgtttcc agtaatcaat cccggatttt ttagtttcac tcatgttctt
    28861 cacctttaca gagtgttcct tgtgaacagg tatcgctgca gccgcagcga tacacataat
    28921 taggacaatt tatgattggc cattaattcc agcgcctgta ccattgccga atgatcaagc
    28981 tggctcccgc catttgccgc acaggtattg aataattcct ggcaggtcgc cgtattcggt
    29041 aaattcagcg ccagcgcttt tgcgctttgc aatgcaagat taaggtcttt ctgatgaagc
    29101 gcgattttga aaccaggctc gaacgtccgg ttgatcatcc gctcgccgtg aacttccaga
    29161 atgcgtgaag aggcgaaccc gcccattaac gcctggcgca cgcgtaccgg atcggcgcct
    29221 gcttttgaag caaacactaa ggcttcagaa accgcttcaa tattcagcgc aacaataatt
    29281 tggttagcca ccttacaggt ttgcccatcc ccattgccgc ccaccagggt gatatttttt
    29341 cccaggatgt caaagagcgg tttaacgcgg tcaaagactt tctgctcgcc gccgaccata
    29401 atcgacagag tgccttcacg cgccccgatt tctcccccgg aaaccggggc atccaggtaa
    29461 tcagcgtcca tttcattaac gcgctgggca aaacgtttgg ttccgatagg agaaatagaa
    29521 ctcatatcga cgatggtttt tccctgaagc gatgttttgg cgcaaccgtg ttcgccaaat
    29581 aacacctctt caacctgcgg cgtatccggc accattatga agatgatgtc tgcgaattca
    29641 gtcacctgac gtgcagtctc aacatttacc gcccccagcg agagcagttc gtccgcgact
    29701 ggaccaatag tcgtaacgtg taattgatga ccggcgcgtg ccaaattgat agccattggc
    29761 gagcccataa ttcccaggcc aataaatccc agtttcatat acaacctctt ttattgcttt
    29821 cggtgtttcc agattcaggc aacacaatcc ccttccaaca cagtggaaaa aaaagcgctg
    29881 cccgaattat tctgcgtttt aacggtactg attaatccac gataatcccg cttccgcggt
    29941 agtcagtggt ttatattcac atccaaccca gccatcataa tcagactgtt taatgacatt
    30001 aaaaataaag tcataattga tttccccggt ccccggctcg ccgcgacgcg ggttatcagc
    30061 aatctgtaaa tggcctattt tatcggccca tgccgtcatg gtttgcgtta attccccttc
    30121 catgcgttgc atgtgataaa tatcatactg aattttgata ttatcgctgc cgatatcctt
    30181 aattaatact aacgcctgtt gagtgccggt gagatggaat cccggcatat caaagtgatt
    30241 aataggttcg ataagtaata aaatgtcttc tttcgccagc atatttgccg catagcgcag
    30301 gttttcgacc aacgtgtcgt agatctccgt tgcggagaat cctgacggcg ttttacccac
    30361 cagacaattt attttcttat tgcctaacgc gcgtgcatag cggattgcgg ccgctacgcc
    30421 atcgcgaaac tcttcttcgc gcccaggaat acaggcaatt ccacgttcgc cagccgccca
    30481 gtcgccagcc ggtaaattat gtaacgtatg ttccagatta ttatccctga gcttacgttt
    30541 taacacttcg atgtcgtcat cgtagggaaa catgaattcc acgccgcgaa atcccgactg
    30601 cgccgcttta tcaaagcgtt ccaggaaatc atattccgta aacagcatag aaagattggc
    30661 agagaaacgt aacatcgatt acctccctta ctcatatttc ataaaacagg tttctgttgg
    30721 cgcatctttc gcactatccg caacctcttc aaactcggtt acgttatcca gttcgtcgcc
    30781 catggaaata ttggttacgc gttccagaat gacttccacc accaccggaa cgcgatattg
    30841 cgccatcagc gctttagctt gttcaaatgc aggcgcaata tcttccggtt taaagacacg
    30901 aattgcttta cagcctaacc cttctgccac ttttacatgg tcaacgccat agccattcac
    30961 ttcgctggag ttgatatttt caaaggcgag ctgcacgcaa tagtccatgt caaatgcgcg
    31021 ttgcgactgg cgaatcagac caagataagc gttgttaacc agcacatgga tatacggaat
    31081 gttaaactgc gcgccgacgg ctaactcttc aatcaggaac tggaagtcga aatcgccgga
    31141 aatcgccacc acattgcgtt gtggatcggc agcacaaacc cctaatgccg ccgggattgt
    31201 ccagccaaga ggccccgcct ggccgcagtt gatccagtgt ctgtctttaa acacatgcag
    31261 catctgcgct gccgcgattt gcgacaatcc aatggtggtg acatagcaca catcgcgacc
    31321 aaaggctttg ttcatctctt catagacgcg ctgcggcttc actggcacgt tgtcaaagtg
    31381 ggttttacgc agcaaagtcc gtttacgctg ctggcattcg tccacccagg tcttccggca
    31441 tggcaaacgc cccgcttttt gcatctcctg cgcgacatcg atcagcaacg ttagcgccgc
    31501 tttggcgtca gaaacgatgc ccagatccgg gcacaacacg cggccaattt gcgtcggttc
    31561 aatatcgata tggatgattt ttcgaccctg agtatatttc tcaacggacc ccgtatgacg
    31621 gttggcgaaa cggttaccga tgccaaaaac catatcggat gccagcagag tggcgttgcc
    31681 gtagcggtgc gccgtttgca ggccgaccat ccccgccatt aaggggtgat cgtccagggt
    31741 acagccccag cccatcaggg tagggatcac cggtacgttg atcagttcgg caaactgctg
    31801 cagcagtggc gcggcgtcgg cgttaataac cccgccgccc gcgacaatta ccggacgctc
    31861 ggactgaatc agcatctcca gcgccttttc aatctgtact cggctggcgg ctggcttata
    31921 taccggcagc ggctcataca tatccggatc gaattcgatt tccgcaacct ggacatcaaa
    31981 cggtaaatca accagcacag gacctgggcg gcctgagcgc atcagatgaa aagcctgctg
    32041 taatacgcgc ggcaccagcg ccgcctcacg aaccgtcact gccatcttgc tgactggttt
    32101 tgcaatcgct tcaatatcga ctgcctggaa atcttccttg tgcagacgcg ctcgcggcgc
    32161 ctggccggta atgcataaaa tcgggataga gtcggcagaa gcggaataga gcgcggtgat
    32221 catgtcggtt cccgccgggc cggaagtgcc caggcagacc ccaatattac ctgccgccgc
    32281 acgtgtgtag ccctcagcca tatgcgaagc gccttccaca tgacgcgcca gtatatggcg
    32341 aatgcctcca tgcttacgca ttgcagaata gaaggggttg attgcagccc caggaacgcc
    32401 gaatgctgtg gtgatacctt ctttttccag cacatacatt gccgcatcca cggctctcat
    32461 ttttgccatt ttattgctac ctctttttat tggaaaaagt ttccaacttt taaaaatttt
    32521 aaaaaagtcc cgctccagcg agcgggatgc ggctcaggct acagggggtt ttagcccaag
    32581 cgccgtactg atgtctttcg cggtatcccg taccagttca ccctggctga taaagcgatc
    32641 ttccgtcagc cgggaagccg gtcccgatat tgagatagcg gcgaccacgc tgcccgcatc
    32701 gtcatagata gcggaggcga tacaattcag cccgacaaca tgttcttcct ggtcaacggt
    32761 atagccctgt tcacgcgccc gctccagatt tttaagcagg ataggtaaat ccaccaaagt
    32821 ggtcggcgta aaccgccgca aaccagtatt gacaacgatc cccaccagct cttcttcggt
    32881 gagcgggtaa agcagcgctt ttccggcgcc ggaagcatgt aacggcagac gactccctaa
    32941 gggcgcgcac attctgacca tcgatttgca ctccttttga ccgattaaca ccgcttcatt
    33001 accgttgcga atcgctacgt tgaccgtctc gccagaaagc agcataagtc ggtgcataaa
    33061 gggcccggcc accgagagga catcgcgatt atgaatatac gcagagccca cattaaatac
    33121 gcctaaacca atatgccacc agccaagctg gctatcctgg tacacaaaat cagccgcttg
    33181 cagtaccttt aacaggcgaa acgtcgtaga aagcggtaaa tccaggctgc cggaaatatc
    33241 gctaactgat gaactgccgc cgcttctttc gagatattgc aatatcgcta tgcccctctc
    33301 cagcgcctga gcgcctttct gcgcagtcgg ctctgcctgt cctggcctgc cgcgtcgtct
    33361 tacttccgtc atatttacgt taactccggc ccaaaatatg agcataaaca atgaacaata
    33421 tgttcatctt atgcaagaag gccaatagcg tcacgcaaaa cagagttcat gtgtcgggat
    33481 actttcaaca tcacagttat cgctgccacc gcgatccacc gtcagaaaat cggtaaccgt
    33541 ctgccacgca aacagcgggt gatgccatac attacggtga taattgacgc cctgccgtcc
    33601 attgctaata aacgcccgca gcgtggagag atcgggttta tcatcgccga gcgcgacaat
    33661 aacgacaaaa gcctcgccgt tcatcggcac aaacgcctgc gtacctaaag gatgacgttc
    33721 cagttcatgt accacaatag gcatcgcggc tggttgcgcc ctgttaatac tgatcagcgt
    33781 gcgatcctgc tccagaactt caaccttcgc caggtcgtga tatcgctcaa ctaacccgtt
    33841 gtttatatga aaaagtcacg ttcctgcgtc tcaataacat cgccataggc gctgaacgtc
    33901 ttctgatcta acggtaatac ctcaagtttc attatttttc ccttgtagct cgattccgtt
    33961 taaccgcggt ttggactctg tccggtttca ataccatgca atctaaaacc ttcgggattt
    34021 aacatcaaca taaaacttgg aatatttttc caaaagtaga tttagaccac aaatcaaaca
    34081 tggctattat gtaaaactac ttaaaaatca taggaaaaca attctggttt tatcaggatc
    34141 gtaaggaggc gtctgacgat gtttgacccg gaaacactgc gtacctttat cagcgttgcc
    34201 gaaacgggga gtttctccaa agcggcggag cgcctgtgta aaaccacggc aactactagc
    34261 taccgcatca aactgctgga ggaaaatacc ggcgtagggc tgttctttcg cacaacgcga
    34321 agcgtctcgt tgacggcggc gggctctcac cttctctctc aggcaaaaga ctggcttgcg
    34381 tggctggaca gcatgcctga cgagctacgc caggttaacg acggcgtaga gcgtcaggtc
    34441 aatattgtgg tgaataacct gctctatagc ccgcaagcgg tcgccagtct cttatcgtgg
    34501 cttaatgcgc gttacccttt cacccagttt cacttttccc ggcaaattta tatgggcgtc
    34561 tgggattcgc tcctgtatga aggtttttcg ctggcgattg gcgtaactgg caccgagccg
    34621 ttggctaata cctttatgct cgacccttta ggttccgtac aatggcgttt tgtgatgtcc
    34681 gcggatcatc ctttagctca cgtcagcggg cctctaacag aagcgcagtt gcgccgtttc
    34741 ccggcaatta atatcgaaga cagcgcgcgt acgctgacca agcgggtagc ctggcgcctt
    34801 ccggggcaga aggaaattat cgtgcctgat atggaaacca aaatcgccgc tcatctggca
    34861 ggcgtcggta tcggttttgt tccgcagccg ctttgtcaaa cgctgatcga caaaaacgaa
    34921 ctggtgagct gtaccatccc tacgatgcgt ccgccctcac cgttaagcct cgcctggcat
    34981 aaatttggcg gaggcaaagc ggtagaagac attgtgaaat tatttaccca acgacaaccc
    35041 gaaatagccg gttttttatc cattttcaac acggtacgct gttaaaaatc aagccacttt
    35101 gcgaattggc gcgtaaaata gcgcaaagga tgatttaagg ttacgtttta cgttatgcaa
    35161 gacagacaaa aagcacagga ctatcgcgca ctcctccttg ccgatacgcc tttaattgat
    35221 gtacgcgcgc cgattgagtt tgaacagggc gccatgccgg gcgctatcaa cctgccattg
    35281 atgatggacg acgagcgggc cgccgtcggc acctgctaca aacgtcaggg cgcggatgcg
    35341 gcgttagcgc tggggcatcg gctggtttgc ggcgacattc gccagcagcg gcttgaggcc
    35401 tggaaagccg cgtatcaacg tttccccaac gggtatctgt gctgcgcacg cggcggtcag
    35461 cggtcacata tcgtacaacg ttggctgcaa gaaacaggga ttgactgccc gcttattgaa
    35521 ggcggctata aagcgctgcg ccagacagca attcaggcga cctggcaact ggcgcaaaaa
    35581 ccgatacttt taattggcgg ctgtacgggc agcggcaaaa cgcaactggt acgacaacag
    35641 cccaacggcg tggatctgga aggtctcgcg cgtcatcgcg gctcctcttt tggccgcacg
    35701 ctgaaacccc agctcagcca ggccagtttt gaaaacaaac ttgccgttga attgctgaaa
    35761 attaacgcgc gtcagacgct aaaaaggtgg gtactggaag atgaagggcg aacgatcggc
    35821 gccaaccatc tgcctgagtg tttacgcgaa agaatggcgc aagcccccat tgcggtagtg
    35881 gaagatccgt ttgcgcttcg tctggaacga ctgcgtgaag agtatttcat ccgtatgcat
    35941 cacgacttca cccacgccta cggcgatggg gccggttggc aggcatatag tgaatatctt
    36001 catcatggac tgttcgctat tcgccgccgt ctggggttgc aacgctttgc cgaactgacg
    36061 gacacgctgg atagggcgct ggcagagcaa ttatccagcg gcagcaccga cggccatatg
    36121 gcatggctgg ttccgctact taacgaatat tacgacccaa tgtatcgcta tcaactggag
    36181 aaaaaagccg cgaatatcgt ttttcgcggc acatggcaag acgttgccaa ctggctaaaa
    36241 gcgcaatagc ttatttttat tgccggctga cgctacattg agccggctta gtgtctgtcg
    36301 cgcttgtcgg cacgttttgc cagccagtcg cccagcatct gaacgacctg aaccagcaca
    36361 atcagcgcca ctacggtaac aaccatcact tcggtttcgt aacggtagta gccatagcga
    36421 atcgccaggt cgcctacccc gccgccgccg acaatcccgg ccatcgccga gtagccgatt
    36481 aagcttacca gcgtaatcgt caggccgcgc agcagccctg cgctggcttc cggcaacagt
    36541 acggtacaga taatacgcat cggactagcg ccgaatgcca gcgccgcctc aataatccct
    36601 ttatcgactt cacggagcgc gctatctacc aggcgtgcat aaaacgcgat tgcggccacc
    36661 gacagcggga cggaggctgc aatcgggcct atcgtattgc ccagcaaaag ctgcgttagc
    36721 ggcagtaaca gcaccagtaa aataacaaat ggcaccgagc ggataatatt caccagaacc
    36781 gaggcgacaa gataaataaa acggttctgc cagaacagat gacgatcggt gacaaaaatc
    36841 agaaaaccga gcggtagacc gccaagaatc gccagcaccg ttgaaatact caacatctgg
    36901 aaagtttcat tgaacgccag cgttaaatcc ggcaataaat catccacgga tcacctccac
    36961 ctgtgcagta cgttgacgga tatgctccac ggcggccgcc accgccgttg gattatgcgg
    37021 cgcggttaat tgcaccacca gaatgcccaa cgcgcgttcg ccgatatact caatcttgcc
    37081 atgcaggata ttgaccgcga cgccaaactt gatcgccacc tccgacagta ccggctgctc
    37141 cgccgaatcg ccgataaaca aaattttcag caactgcccg ggcaggtgtt cccgtaagcg
    37201 ttccggcagg gtcaaattaa gggtatgaga caccagttgc tgtgtgaaag cgtgttgcgg
    37261 gtgggcaaac acatcaaaca cctcgcccga ttccacaacc ttaccgcccg acatcaccgc
    37321 cacgcgatcg caaatagatt tgatcacgtt catttcatgg gtgatcagca caatagtaat
    37381 cccgagctgc gcgttgatct gtctgagcag ggccagaatc gtggcggaag tttccagatc
    37441 cagagcggaa gtcggttcgt cacacagcaa aacatccgga tggttagcga tggcgcgggc
    37501 tatccccacc cgctgttttt gcccgccgct gagctgtacc ggaaaacagt tcgctttatc
    37561 ggcaaggccc accagcgtta aaatttccgc cacccgcggc gcgattttgc tgcgttccca
    37621 gccagccgct ttcaggctaa acgccacgtt tttcgccact gtccgggtat gcattaagtt
    37681 aaaatgctgg aaaatcatac caatacgctg ccgcgcctgg cgtaacgctt ttccgtccag
    37741 cgcagaaatt tccacgccgt tgacgttgac gcgcccctga ctgggacgcg ttaaggcgtt
    37801 cagggtacgc agcagagtgc tttttcctgc gccgctggta ccgacaatgc caaaaatctc
    37861 gcccgcggcg atatgcaggc tcacatcatc caccgcgcgc gtgggggtac cgcgaccggc
    37921 ggtaaaatcg acgcagactt tttctatttc aatcatattc acctcagaaa ttggggatgg
    37981 ccaccgctgc gatcagggtg tcgcggtcat ccattccggt ttctggaagg cgctataaat
    38041 attctttgga tcgtcgatga ccgcgcgata agccggcgat ttcaccgcct cgacaatatc
    38101 tttggcaaac ggcttatcgg catcttcact gcgtaccgca atgatatttt tcagattctc
    38161 atccaggtgt tcctgcttaa tcgcgctgga gagatcgagt cctgccgcca ccgcaaagtt
    38221 cccgttaacc agcgcgccgg tcacgccgtc cagcgtgcgc ggtagctgtg cggcttccag
    38281 cggtttgaaa accagtcctt ttggattgct ggcgatatct cgttcagagg ctttggtcgg
    38341 atcgatattg tgcttaatcg tgataagccc caacgattgc aggaagcgaa ggccgcgcgc
    38401 caggttggtc ggatcgttgg agagggtaat aatgtcccct tttttaagcg catccaggct
    38461 gttgatttta cgtgaataga agcccatccc ggcggtcggt accacaataa gtttgctgag
    38521 cttcagccct ttgtcagcgg tgaatttgtc aaaatagagg gtatgttgaa agaggttggc
    38581 gtcgatgctg ccgttagcta acgccatatt gggctggaca tagtcgctaa actcgcgcac
    38641 cacgacctta tacccttttt cttttaatgt cggcgcaatc gcctgcttca ccatgtcgcc
    38701 atacggccct ggcgcgacgc caaatacgat cgtttgcggg gaaccatcgg catgggcaaa
    38761 ctgtaatccg caggccagta atagcgtgct ggccgcaatg cgtaaactct gacgcaatcc
    38821 cataatttct ccattttaaa tagtgtgatg ctgtgccgga tgccgttcat gcggcatcgt
    38881 ctgttttggc ccaaacgaaa ggctatttct taacatgaca cagatcacag cctgctgtcc
    38941 ttgaaattat ttcatgatgt ttcctggtgt gtcgttaaat gtacgaggca ggcgctcagg
    39001 cgtgtgtcag gcgggaatgg cgtaaaggga aatgccggat aagacgtctt aacgccaaca
    39061 tccggcacag gaaaacgctt tagaaatcgt aacgcagacg caccaggttc atatcgccca
    39121 gattgtcagt gctggaggtg aaaacatgtt cataatcaac gcggaaacca taatccagtt
    39181 ggaaggtgat ccccacgccg ttatcggtgc gcagatagtc gcggccattc acatattcaa
    39241 tgcggtcgcc cataaagtac ggttgaatag ctttcacggc atactgacca atcgggaaag
    39301 cgtaaccgac aaaatattcc agaccccacg catcgccggc aaagtaatca ttcacagaca
    39361 cttttttggt cgtcataaag ttctgatacc aaccgccgcc tgcggcaata gtccagtttt
    39421 ccggcgtcca gcttaacgcg gtaccgacaa tattttgatc gtaagtttta ttgccgttgc
    39481 cgcgcatctc cgcacgggta tagttccatg ccgtccccca ggtcagatcg tcggtgagat
    39541 ggtaatccgc gcctaaagaa ccgccgcctt tacgtttgta attcaggccg ttattggcat
    39601 tataatcgtc gctgaacaga taagacgcgt agagatcgac attgccaatg cttttcttat
    39661 acttcaatga cttacgcgta cggtaagaac catcgtagtc gccgttaatc ccgttgcccg
    39721 gcgcctgacc tatcatgtcg taatcccaga tatcggtttt tacgcccacc acatcgtaat
    39781 aaatgctgtt ctgttgaccg aaggtcagcg ttccccacgt cgcgctcttg aagccagtat
    39841 acagcatacg gcgagtggta tcagtcgtgc ccttcgcata atggttatcc cagtcaaata
    39901 ccgcagggat attgacgccc agctcgtaat agctaatcca actgatatca tcaaacagat
    39961 aataatccgc ggcgaagcgg aaacgcgtcc cgccatcaaa accattacgt ttataaccgt
    40021 tcgcgccgtc attaccggtc atattctgga actgcggacg aatactcccg ccaacggtga
    40081 aattgagtcg gctgagtgga ttacccgcct ggggatcttg ttttaaaacg gtgatttccg
    40141 cctgagtggc gaaaggcatg aaagccactg ccgcgccgat cgatgccgcc aacgctgtta
    40201 ttttaattgt cattatattt tccttgatag atagccaatc caaatcattt agcaggcaaa
    40261 taataactgt tataaaacct tacgtgttgt gtatttttta atgatttgtg ctactaaaaa
    40321 tcaaggagtt atcaatttgt gcgactaaaa aagtacgcgc cgttttaaaa accagcgcga
    40381 aattattcac atcatgaatc atccgctaaa ctggcggaat agcgctttgc ctttaagcaa
    40441 acgaacgcca agccagccgc cgcatacgga aagcagcagc gcgccgcaaa acggcagtgc
    40501 gacccataaa cgccagtccg gctcccaggg gaaatcaaaa acgttgattt gtaagatcgc
    40561 cagcgccgtc tccgcgccaa tcgcggcgac cagcccggca actaacccca gcatggcgaa
    40621 ttcgcaccag agtgtggtac gcaacagttt ctttccggct cctaacgtgc gccacaccac
    40681 cagctcctga tggcgctgac gcatcccgac ctgtacctgg gccagtaata gcaacatgcc
    40741 gcagagagtg actagcacaa ccatcacctc cagcgcccga ctgacctgct ccagcacctg
    40801 tcccacctgt ttcaggatcg ccccgatatc taacaggctg acggtaggaa actcgcggtt
    40861 aagctgcgtt aacatgccgt tgccattctc ccagcgaaaa ctggtcaacc agctttgtgg
    40921 ttgcccgtcc agcgccccgg aaggaaaaat gaagaaaaag ttgggccgca ggctttccca
    40981 gtccacttga cgcaggctgg tgactttagc gctaaatgcc tgggtatcgc ccataaaggt
    41041 tacgctatcg ccgagtttga cgttcagccg cttcgccagc ccctcttcca tagagacttc
    41101 gcccggtttt ggcggccagt gaccggcgac cagcggatta tgcgccgggc gcgtatcctg
    41161 ccaggtcaaa ttcagttcac ggttgagcga ctcatcctgc tgaccttccg tcggattacc
    41221 gtttatctcc gttaaccgcg cccgcacaat cggataaaac gtctgcggga tcacctgatg
    41281 ttccgccaaa aaggctttca gcggcgcgac ctgttctgaa gcaatattga taaggaaata
    41341 gttcgggctt tccggcggga gctgctgttg ccagcgatca aggaggtcgc cgcgcagcac
    41401 cagcaagagc gccagcagca taaacgaaag cgaaaacgcc gaaagctgac tcaacgttga
    41461 ccacggctga cgcagaagtc ggctgacggc cagacgcagc ggtagcgacg tcaacgtcat
    41521 gccgcgcaac acgttaagca gcatccagcc caccagaccg cacagcagcg ccagtatcac
    41581 ggcgcccgcc agaaccgccc acaacagcat actttcgccc atcaatccgg cgagcagcgc
    41641 caccacgacg gcgcaggcga caggcaaata aatttttaac gaccagacgc gagcgacaac
    41701 atcgcggcgc agcacccgta gcggctggct cgccagcaac aatcgataag gccgtaaacc
    41761 gaccagcaga gagatgaccg tcatcgcgcc cagcgcccac agccagggcc acaggctggc
    41821 gggcggcaaa tcggcgggca ataccggttt tagcagcacc agcaatatgt tttcaaacag
    41881 taacccaatc gcgcctcccg tgacggcgga aagccccagc accatcaacc actgtccgat
    41941 gataagttta cgcaactggg cccggcccgc gcccaacgtt tttaaaatcg ccaccagatc
    42001 gtagcggcta cggcagtaat ggctcatcgc caccgcgacg gcagctaccg ccagcagtag
    42061 cgttaataac gccgaaagca gcaaaaactg ctgcgaacgt tcgagcgatt tccccaatgc
    42121 cccgtcatcc tgctccagtc cgtaccagcg atgttccggt ttaagctgcg gtaacagcca
    42181 gctttcatag ccagcaagct gttgcggcgt tccgccgaat ttataccgcc acatcacgcg
    42241 actccccggc tgtatcgcac cggtttttgc cacatcggcc atattcatca tcagacgcgg
    42301 cgccatctga aaagggttaa atccggaatc cggctcctgc accacttcac cagcaatacg
    42361 caaggtcacg tcgccgacat caatggtatc gcccgttttc aaattaagca gcgccatcag
    42421 acgcggcgcc agcagtacgc tacccggctg cggtttcact ccgcctggac gggtttgcaa
    42481 ttcgccgtac atcggataaa cgctatctac cgccttcacg ctggccagtt gcggcgtatc
    42541 gccggcaaac gtcatggtcg caaaggttaa ctgctcgccc acgttaaggc cgcgtttacg
    42601 cgcctcttca agccaggctt tcggtacctc ccgcgaactt tgcagcgtcc gatcgcctgc
    42661 cataaactcg cggctttgct gacttaaccc tttttccatc cggtcgctga tactgccgag
    42721 cgccagtacg caggccaccg ccagactcaa cgccagccag acaataatca gcgacggcga
    42781 gcgccattcg cgccagaacc agcgggctat catgcctcct cctgtaactg accgttgacc
    42841 aaccgtagcc gccggtcgca gcgcgccgcc agcgccgggt cgtgcgtcac cagaatcagc
    42901 gtagtgccgt gctcgcggtt aagcgaaaat agcaggtcgg cgattttatc tccggtctga
    42961 cggtcaaggt tgcccgtcgg ctcatcggca aacagcacat caggacgccc gttaaacgcg
    43021 cgcgccagcg ctacgcgctg ctgttcgccg ccggaaagct gtgccggaag gtggtcaagc
    43081 cgttttccca gtcccagttg ttcgagcagc gctttcgccc ccgccttact ctgaccgctg
    43141 ttttcaccgc gtagcagggc cggtagctca acgttttcca gcgcgttaag cgtaggaata
    43201 agcatgaagg attgaaaaac aaaaccgaca tgctgagcgc gaagctgcgc ccgcgcctct
    43261 tcgtccatct gatgaagcgg tttcccgacc agactgacct ctccgctact gccgtcatcc
    43321 agtccggcga gaatcgccag cagcgtagat tttcccgatc ctgattcgcc aatcagcgca
    43381 atggtttcgc cgcgtttgac aaccagttca actccggtaa ggatggaaag ctcatgctca
    43441 ccctgaccga cggacttcct gagacgatga acttcaacac tgttttccgc tggcatttgc
    43501 ccttcctgtt tttgatcctg ttaactttcc gtgccgccgc cgcagacacc ttattaattc
    43561 tgggcgatag cctcagcgcc ggttaccgta tgaccgccag cgcggcatgg ccgtcgctcc
    43621 ttaatgataa atggcaaaac aaaacgtcgg tcgttaatgc cagtataagc ggggatacct
    43681 cgcagcaggg actggcgcgt ttgccggcgc tgttgcaaca gcatcacccg cgctgggtag
    43741 tggtggagct tggcggcaac gatggcctac gcggttttgc gcctgcgcaa accgaacaga
    43801 cgctacgtaa aatcattcag acggtgaaag ccgccgatgc ccaaccgtta ctgatgcaaa
    43861 ttcatctgcc cgctaactac ggtcgccgtt ataatgaatc ctttagcgcc atttatccta
    43921 agctcgccaa agagttcgat attcctctat taccgttttt tatggaagag gtatatctga
    43981 aaccacagtg gatgcaggat gacggtattc atcccaaccg cgacgcgcag ccgtttattg
    44041 ccgactggat ggcgaagcag ttgacccctt ttctctcctg aatcattcga gttgcatgaa
    44101 ggcggcacgt aagagaattt ccaggagcat agatacctat gtgactggag taaacgaacg
    44161 cacaggcaac ttgaagtatg acggatatag ttaaccacga ctcttaaatc aacggagatc
    44221 ctgacaggta aagttatgca aaaatcggtc ttaataacag gatgttccag cggaatcggt
    44281 ctggacagcg cgcttgaact taaacgccag ggctttcaaa tcctggcggg ctgccgcaaa
    44341 cctgatgatg tcgcccggat gaacagtatg ggatttaccg gcgtgttgat cgatctcgac
    44401 tcccctgaaa gcgtggatcg tgccgccgat gaagtgatcg ccctgaccga taatcgtctg
    44461 tatgggatct ttaacaatgc cggctacggc gtgtatggcc ccctttccac catcagccgt
    44521 gaacagatgg agcaacagtt ttccagtaat ttcttcggcg cgcatcagct taccatgcgc
    44581 ttacttcccg ccatgttgcc gcatggcgaa ggacgcattg tgatgacctc atcggtgatg
    44641 gggctgattt ccaccccagg gcgcggcgct tacgccgcca gcaaatatgc gctcgaagcc
    44701 tggtctgacg cgctacgtat ggagctacgg cacacaggca ttaaagtgag cctgatagaa
    44761 ccggggccga ttcgtacccg ttttaccgat aacgttaacc agacgcagcg tgataaaccg
    44821 gtagaaaatc ccggcatcgc cgcgcgtttc acccgcgatc ctgacgcggt agtagcgaaa
    44881 gtgcgtcatg cttttgcaag cgataaaccc aggctgcgct atcccgttac gctggtcacc
    44941 tgggcggtga tggcgctgaa acgcatattg ccgggccgga tgctggataa aattttacaa
    45001 agctgagttg aagcgcgccc gtcagccccc atgtaaacgt gacacagaca aaagagagcg
    45061 acgccatgtc cgtacagaac attgtcaata ttaatgaatc caacctgcag cagaccttag
    45121 agcagtccat gaccacgccg gtactgttct atttctggtc tgaacgcagc caacactgtc
    45181 tgcaattaac gccagtgctg gaaagtctgg ctgcccagta ccacggtcag tttattctgg
    45241 caaagctgga ctgcgacgcc gaacagatga tcgccgctca gtttggtcta cgcgccatcc
    45301 cgacagtcta tctgttccag aatggccaac cggtcgatgg tttccagggg ccgcagccgg
    45361 aagaggcaat ccgcgctctg ctggataaag tactgccgcg tgaagaagag ctaaaagcgc
    45421 aacaagcgat gcagttaatg caggagggca actacgttga cgcactgccg ttactcaaag
    45481 acgcctggca gctatcttcg cagaacagtg agattggcct gttactggcg gaagcgcaaa
    45541 ttgcgctgaa ccgctctgaa gaggccgaag cggtattaaa aactatcccg ctacaggatc
    45601 aggatacccg ttatcagggg ctggtcgcgc agatcgaact gcttaaacag gcggcggata
    45661 cgccggaaat tcagcaactt cagcagcaag tcgcggataa tccgcaggat gcggctttgg
    45721 caacgcaact ggcgttgcag ttgcaccagg tcggacgtaa tgaagaagcg ctggaattgc
    45781 tgttcagcca tctgagaaaa gatcttgccg ccgccgaggg acagacgcgc aaaaccttcc
    45841 aggagatcct tgccgcgctc ggcaccggcg acgcgctggc gtcgaaatac cgccgccagt
    45901 tgtacgcgct actgtattaa tcctctcttg cctgatggcg cgcttatctg gcctacctgt
    45961 cgtcctcagg ccggataagg cgcttgcgcc atcatccggc aactatcatg atttcttgag
    46021 cggcatcact accaactgat gacgcgaatt atagaacttc cggtaggtta aatagcaggc
    46081 aatgatggta gacaggctgg ctgtcgataa cagcataaac gttaccataa tttgatattt
    46141 aatcgctttt accggattga tcccggcaaa aatcagcccg gacatcatcc ccggcaggct
    46201 caccagccca acggtctttg ccgagtcgat cgtcgggata agcgatgcgc ggatgctatc
    46261 gcggataagc ccggcggagg ccattttcgg cgttgcgccc aaacttaatt tttcctggat
    46321 ttgctgctgc tcgctatgaa aacgcagccc cagttggttg tagcacagcc ctaccgccac
    46381 catcgcattg ccggcgacca tgccagcgat gggaatcacc tgcatcggcg caaattcaat
    46441 cgaaccggta agcaccagta ccgtcagcgt tagtccggcg ccgacggtga tggcgataaa
    46501 cgaggagaga aatgccttat cgatatattt actgcgcttt tgcgcgttcc atgcggcgtt
    46561 aaaacagatg aacagcacca tcagtagcgt cagggcggca tgattaacgc caaagatgta
    46621 tttcagtaca tagccgacaa taatgagctg tatcaccgcc cggcatacgc tccacagaat
    46681 atctttttcc agcgccagct tttccttgtg actgatgagc atcgcgacca ccaccagcag
    46741 catcgataac gccagcgagg tattggtaat attatgctcg ttcataacgc gcctcctgca
    46801 tctctccggc agatggcgtt aacgttatca ccttatccgc gtgttgaatt tcatctttat
    46861 catgcgttac ccacaagaca gcgacctgct tatcgcgaac atagcgatga ataatatcat
    46921 tcacattccg tttgttatgt tcatccagcg cgctggttat ttcgtcgagt aacagtattt
    46981 tcggcagaaa ctgtagatta cgaattagag caatacgctg tttttccccg ccggaaagcg
    47041 cggcaatcgg tttttgcaga atcgtctccg gcagttcaaa acgcgccaga tcgtctgcga
    47101 aggctgtcgg ctgcgggcgc tgatggcgaa tttgccaggg aaaaatcagg ttatcgtaaa
    47161 ccgtatcgcc gaatagcgct ggcgtctgag cgcaataaga aacctgctgg cgataggctt
    47221 ccggactcag agtagtaata tcccgcccct caaaaagaat cacgccgata tcagggctta
    47281 ttagcgaggc caccattttc aacaacgtac tttttccgca gccagaagga ccggtaatta
    47341 acttaaattc gccgcgttgc agcgtaaaac tgatgttatt cactattttt gtcgtcgcag
    47401 tctggtaacc gacctgcttt aactcaagca acatgctacg ttttgtcatt tattgcgcat
    47461 ccgttgttca tatttttata gcgatagtgt atccctgtaa ttaataaggg gggaacatgc
    47521 tttactgaat caggtataat tcgcttaatt cgtcagcaaa atcggtttat ggacaacgca
    47581 acaggaggtt tagctatgct cattcttatc cctattctca ttttcgtcgc gctggtgatc
    47641 gtcggcgcgg gcgtcaaaat cgttccgcag ggataccagt ggacggtgga gcgctttgga
    47701 cgttacacca aaactctgca gccgggatta agccttgttg taccgtttat ggacagaatt
    47761 ggccgcaaga tcaatatgat ggagcaggtg ctggatattc cgtcgcagga ggtgatctca
    47821 aaagataacg ccaacgtcac tatcgatgcg gtctgtttta ttcaggttat cgatgcgccg
    47881 cgcgccgctt atgaagtcag taacctggaa ctggcgatca ttaacctgac catgaccaat
    47941 atccgtacgg tgctcggttc gatggagctg gatgaaatgc tctcccagcg cgacagcatc
    48001 aacgcgcggc tgctgcatat tgtcgatgaa gccaccaatc cgtggggaat taaagttacc
    48061 cgtatcgaaa ttcgcgatgt ccgtccgccc gcggaattga tctcctcgat gaacgcccag
    48121 atgaaagcgg aacgtaccaa acgcgcctat atccttgagg ccgaaggggt gcgtcaggcg
    48181 gaaatcctga aagccgaggg ggaaaaacag tcgcagattc tgaaagccga aggcgaacgt
    48241 cagtccgctt tcctgcaggc ggaagcgcgc gaacgttccg ccgaagcgga agcccgcgct
    48301 acgcagatgg tgtctgaagc catcgccgcc ggggatattc aggcgttaaa ctacttcgtg
    48361 gcgcagaaat acaccgaagc gttacagcaa atcggctcgg cgaataacag caaagtggtc
    48421 atgatgccgc tggatgccag cagtctgatg ggcgctatcg ccgggatcag cgagctggtt
    48481 aaggacagcg ccagcgaacg gaaaaaagca tgatagcgat gattctggta catccacata
    48541 tcttctggct tagcctcggc ggcctgttgt tggctgcgga aatgctcggc ggtaacggct
    48601 atttgctgtg gagcggcgtg gcggcagtga ttaccggctt aaccgtctgg ctcttaccgc
    48661 tcggctggga atggcagggc gtgctgtttg cggccttaac gttgctggcg gcctggcttt
    48721 ggtggcgctg gctggcgcgt cgcgtgcggg aacaaaagcc gaccgacagc cgccttaacc
    48781 aacgcggaca acaactggta ggccgccggt ttatgcttga tgccgcgtta gtgaacggac
    48841 ggggtcatat gcgtgtcggt gacagctcgt ggccggtatg cgctgacgaa gacctgcgcg
    48901 caggtacgca tgtcgaagtg atcgccgtgg aaggcatcac cctacgcatt cgcgccgttt
    48961 aatcaacgta acttttgcgc cttgtgatga cagcagccgg aaagattatc aataatcggg
    49021 cagtcggcgc tgtcatcgcc gggacaactc tccgccatcg ccaacagttg atcgcgcatt
    49081 gattgcagct cgctgatatg gcgttcgatc tccgcgacct tttccagcgt ccgctttttc
    49141 acatctgcgc tatggcgtcg cggatcgtta aacagattga ccagttcgcc acactcttcc
    49201 agattaaacc ccacctgcct cgcctgtcgc agcaacgtca gctcgtttaa atgcttctgc
    49261 gtgtaggtgc gataaccatt ttcgctacgt aatggcggcg tcaccagccc tttctcttca
    49321 taaaaccgaa tggctttgct ggttaaaccg gtttttttcg ccacatcgct aatattcata
    49381 tttccccctt gaccttaacc ttgctggaag gtttaacctt tatcacagtg agtcactacg
    49441 attactaatg tcaatgaatt gatgaccaat cataaaggag tttttactat gtctcaaact
    49501 atcgacctga ccctggacgg tttgtcctgc ggtcattgcg ttaaacgcgt gaaagaaagt
    49561 cttgaacaac gtccggatgt tgagctggcg gacgttaccg taaccgaagc gcacgttacc
    49621 ggtaccgcca gtgcggacgc gttaattgaa accatcaaac aagccgggta tggcgcgacg
    49681 ttaagccacc caaaggctaa accgctgacg gagtcatcaa tcccgtcgga agcactggca
    49741 gcggttcctc atgagcttcc ggtagcgacg gccgatgaag aaagccaaca gttgctgtta
    49801 agcggcatga gctgcgccag ttgtgtcacc cgcgtacaac atgcgctaca aagcgtaccg
    49861 ggcgtcacgc aggcacgggt aaacctggcg gaacgcactg cgctggtgat gggcagcgcg
    49921 tccgccgctg atttagtgca ggcggtggaa aaagccggct acggcgcaga ggcgattgaa
    49981 gatgacatca aacgccgcga gcgccagcag gaaaccgcca tcgccaccat gaaacgtttt
    50041 cgctggcagg ccatcgtcgc cctggcggtc ggtataccgg tcatggtctg ggggatgatc
    50101 ggcgataaca tgatggtgac cggcgacaac cgcagcctgt ggctggctat tggcctgatc
    50161 acgcttgcgg tgatggtttt tgcgggcggt cacttttacc gtaacgcgtg gaaaagcctg
    50221 ctgaacggca cggcgacgat ggatacgctg gtggcgctcg gcaccggggt cgcctggctc
    50281 tactccatga gcgtcaacct gtggccgcag tggttcccga tggaagcacg gcacctctat
    50341 tacgaagcca gcgcgatgat tatcggtctg attaatctcg gacacatgct ggaagcgcgc
    50401 gcccgtcagc gttcctcaaa agcgctggaa aaattactcg atctcacccc gcccaccgca
    50461 cgcgtcgtaa cagaagacgg cgaaaaaagc gtcccgctgg cggacgttca gccagggatg
    50521 ctgctgcggc tcactaccgg cgatcgcgtg ccggtggatg gcgaaattac ccagggcgaa
    50581 gcgtggcttg atgaagccat gctgaccggc gaacctattc cgcagcaaaa aggcgaaggc
    50641 gacagcgttc atgccggcac cgtcgtccag gacggcagca tcctgttccg cgccagcgcg
    50701 gtgggcagtc ataccacgct gtcacgcatt attcgcatgg tacgccaggc gcagagcagt
    50761 aaaccggaaa ttggccaact ggccgataaa atctccgcgg tattcgttcc cgtagtggtg
    50821 gccattgcgc tgttcagcgc cgctatctgg tatttcttcg ggccggcacc gcaaattgtt
    50881 tatacgctgg tcatcgccac caccgtactg attatcgcct gcccttgcgc attaggcctg
    50941 gcgacgccaa tgtcgattat ttccggcgta ggccgcgcgg ccgaattcgg cgtgctggta
    51001 cgcgacgccg atgccctgca acgcgccagt acgttggata ccctcgtttt tgataaaacc
    51061 gggacgctga cggaaggcaa gccgcaagtg gtggcggtaa aaacctttaa cggcgttgat
    51121 gaagctcagg cattacgtct ggcagccgcg ctcgaacaag gctccagcca cccgctggcc
    51181 catgcgattc tggaaaaagc cggcgatgat aaactgccgc aggtgaacgg tttcagaacg
    51241 ctgcgcggac tgggcgtcag cggtgaagcg gaaggtcatc aactgcttct ggggaaccag
    51301 gcgttactga acgaacagca cgtcgccacg gatgatatga cggcggaaat caccgcgcag
    51361 gcctcgcaag gctcgactcc agtcctgctg gcgattgacg gtaaagcggc ggcgttactg
    51421 gcggtacgcg atccattgcg cagcgatagt attgccgcac ttgaacgcct gcacaatgcc
    51481 ggataccgtc tggtaatgct caccggggat aacccaacga cggctaacgc gattgccaaa
    51541 gaagcgggta ttgatgaagt gattgcgggc gttctgccgg atggcaaagc cgatgcgatt
    51601 aaacgcctgc aaagccaggg tcgtcaggtt gcgatggtcg gcgatggtat caacgatgcg
    51661 cccgcgctgg cgcaggcgga cgtcggtatc gcgatgggcg gtggcagcga tgtggcgatt
    51721 gaaaccgcgg cgattacgct gatgcgccat agtctgatgg gcgtggcgga tgcgctggcc
    51781 atttcgcgcg cgacgttgcg caatatgaaa caaaacctgc ttggcgcatt tatctacaac
    51841 agcattggta tcccggtggc cgccggtatt ctgtggccgt ttaccggtac cttgttaaac
    51901 ccggtagtag cgggcgcggc aatggcgctg tcttccatta ccgtcgtcag caatgccaac
    51961 cggctattgc gctttaaacc gaaagcgtaa aaagtctata cccaaaataa ttcgagttgc
    52021 ttaaaggcgg caagggagtg agtccccagg agcatagata actatgtgac tggggtgagc
    52081 gacaaatctg ccgggagcag atttgaacgt cgcg
//
LOCUS       DAJVKX010000018        51286 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000018 DAJVKX010000000
VERSION     DAJVKX010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 51286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51286
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.018"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            121..1752
                     /gene="dcuS"
                     /locus_tag="OPY25_001002"
     CDS             121..1752
                     /gene="dcuS"
                     /locus_tag="OPY25_001002"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HCS0926669.1"
                     /translation="MKHSLPCRALRKRPMKLGTTVILMVSAVLFSVLVVVHLIYFSQI
                     SSMTRDALADKALAVARSLADSPAIREGLKKPPAESGIQPLSEAVSQHNGFLFIVVTN
                     MQGIRYSHPETQRIGQPFKGDDILLALQGKENVAINRGFLAKALRVFTPVYDEHHRQI
                     GVVAIGLELSHVTQQINNSRGSIIWSILFGALVGLLGTYALVKVLKRILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVIAVDDSGEVTLINHAAQALLDYRKTQDDARLSTLSHAWPQV
                     VDISEVLRDGTPRRDEEIIVKGRLLLVNTVPVRSNGEIIGAISTFRDKTEVRQLMQRL
                     DGMVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEAYIIKTANNYQEEIGLLLGKI
                     KSPIIAGFLLSKITRASDFGHSLVISSDSQLPDNNNEDQVTVLITALGNLIENALEAL
                     SQESGGEISVSLHYRHGWLHCEVSDDGPGIEPERIEAIFEKGVSSKGAERGVGLALVK
                     QQVEALGGVISVESEPGIFTQFFVQLPWDGKRTSL"
     gene            1749..2468
                     /gene="dcuR"
                     /locus_tag="OPY25_001003"
     CDS             1749..2468
                     /gene="dcuR"
                     /locus_tag="OPY25_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HCS0926670.1"
                     /translation="MINVLIVDDDAMVAELNRRYVAQISGFHCCGTASTLEKAKEFIF
                     NSENHIDLILLDIYMQQENGLDLLPVLHSAGCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQATRFEEALTGWLRKKTAMEKRQYYEQSELDLLIHGNSSSEQEPRRLPKRLT
                     QQTLRTLCQWIDAHQEQEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRVQPEHYSLLKQYCQ"
     gene            2785..3051
                     /locus_tag="OPY25_001004"
     CDS             2785..3051
                     /locus_tag="OPY25_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926671.1"
                     /translation="MDNTYIGEQIRVSTRHTNNLKKWRDNDHISHILFNLSRDLPDGE
                     TQKLNNKRLFLKQTNHNLLLSLTPPAHRQRVLPSEHHHRKKIIT"
     gene            3198..4538
                     /gene="dcuB"
                     /locus_tag="OPY25_001005"
     CDS             3198..4538
                     /gene="dcuB"
                     /locus_tag="OPY25_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HCS0926672.1"
                     /translation="MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGKHLEFLDLLSITIPSTLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQY
                     VYGDTATLLDKKLPKSNWLAMWIFLAAIAVVALLGADSDLRPTFGGKPLLMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTRIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            4634..6280
                     /locus_tag="OPY25_001006"
     CDS             4634..6280
                     /locus_tag="OPY25_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HCS0926673.1"
                     /translation="MSKKEFIYQAPFPMGEDKTEYYLLTSDYVSVSEFNGESILNVEP
                     QALTLLAQQAFHDASFMLRPEHQQQVAAILHDPEASENDKYVALQFLRNSEIAAKGIL
                     PTCQDTGTAIIMGKKGQRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAPLDMYKEVNT
                     GSNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAESTLKTVKLASTHYYDALPTEGNEHGQAFRDLHLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPPALRQAGEGDAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKERIESGEDLPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQQSIKHLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVSKQCANCAK"
     gene            complement(6378..7808)
                     /gene="melB"
                     /locus_tag="OPY25_001007"
     CDS             complement(6378..7808)
                     /gene="melB"
                     /locus_tag="OPY25_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="melibiose:sodium transporter MelB"
                     /protein_id="HCS0926674.1"
                     /translation="MSISLTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLV
                     GTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLTNSLVLFLLFSAHLFEG
                     TAQVVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPFPRFFASLAGFVTA
                     GITLPFVNYVGGADRGFGFQMFTLVLIAFFIASTIVTLRNVHEVYSSDNGVTAGRPHL
                     TLKTIVGLIYKNDQLSCLLGMALAYNIASNIINSFAIYYFTYVIGDADLFPYYLSYAG
                     AANLLTLIVFPRLVKMLSRRILWAGASVMPVLSCAGLFAMALADVHNAALIVAAGIFL
                     NIGTALFWVLQVIMVADTVDYGEFKLNIRCESIAYSVQTMVVKGGSAFAAFFIALVLG
                     LIGYTPNVAQSAQTLQGMQFIMIVLPVLFFMMTLVLYFRYYRLNGDMLRKIQIHLLDK
                     YRKTPPFVEQPDSPAISVVATSDVKA"
     gene            complement(7892..9247)
                     /gene="melA"
                     /locus_tag="OPY25_001008"
     CDS             complement(7892..9247)
                     /gene="melA"
                     /locus_tag="OPY25_001008"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCS0926675.1"
                     /translation="MMTAPKITFIGAGSTIFVKNILGDVFHREALKSAHVALMDIDET
                     RLEESHIVVRKLMDSAGASGRITCHTHQKAALQDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPKATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPASLRYRCVGINHMAFYLELERKTADGT
                     YVNLYPELLAAYDAGQAPKPNIHGNERCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIARYKVPLDEYPKRCVEQLANWHKELEEYKTAERIDIKPSREYASTIMNA
                     LWTGEPSVIYGNVRNEGLIDNLPQGSCVEVACLVDANGIQPTKVGTIPSHLAAMMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIEEIYALVDDLIAAHGDWLPAWLR
                     R"
     gene            9516..10448
                     /gene="melR"
                     /locus_tag="OPY25_001009"
     CDS             9516..10448
                     /gene="melR"
                     /locus_tag="OPY25_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HCS0926676.1"
                     /translation="MSTQAISLLPPDPHMCNGDEKQTRSPLSLYSEYQRLDVELRPPH
                     RMASSHWHGQVEVNVPFDGDVEYLINNEVVQIKQGHITLFWACTPHQLTRPGNCRQMA
                     IFSLPMHLFLSWPLDRDLINHVTHGMVVKSLATQQLSTFEVLRWQQETSSPNEQIRQL
                     AIDEIGLMLKRFSLSGWQPILLNKTSRTHKNSVSRHAQFYVSQMLGFIADNYDQALTI
                     NDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKTILDVALTAGF
                     RSSSRFYSTFSKFVGMSPQQYRKLSQQRRQTMPG"
     gene            10681..12948
                     /gene="adiA"
                     /locus_tag="OPY25_001010"
     CDS             10681..12948
                     /gene="adiA"
                     /locus_tag="OPY25_001010"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HCS0926677.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     YAILSANEAIDCLMFSYQMEQPDEHLSVRQLIGKLHERQQNVPVFLLGDREKATASLD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFNALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRSDMGIERTTLGSLLDHTGAFGESEKNAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVLDRNCHKSIEQGLILTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKISASPLTKTKAGQKPSYSVVTNCTYDGVCYNAKEAQ
                     DLLAKTSDRIHFDEAWYGYARFNPIYCDHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAVNFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTDEGDWFFKPWNKDVVTDPQTGKTYDFADAPAKLLATDQN
                     CWVMRPGETWHGFKDLPDNWSMLDPIKVSILAPGMGDDGELEASGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLINTLCSFKHHYDANTPLAQVMPELVQDYPD
                     TYANMGIHDLGDKMFAWLRENNPGARLNAAYSTLPVAEITPRDAYNAIVNNNIEMVAI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDENSPQVGYLRSLQSWDHHFPGFEHETEG
                     TEIIDGVYHVMCVKA"
     gene            13245..14006
                     /locus_tag="OPY25_001011"
     CDS             13245..14006
                     /locus_tag="OPY25_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCS0926678.1"
                     /translation="MRICSNEPCIVLLTEKDTWLRVNGKEPISLKANHMAILACENNV
                     IDISSLNSVLVIQVSRNNIKDYLQFLNKDLSHLPVWQRNADPLLTATCLTPDIFRVAA
                     RYSAMETPDEIVSERTRALLFTVLSRFLDHKKFISLLMHMLRSRISDSVYHIIQSDIH
                     KDWNLSAVASCLCLSPSLLKKKLKNENTSYSQIITTCRMRYAVNQLLMDGKNISQVSQ
                     LCGYNSTSYFISVFKEFYGMTPLHYVSQHRERSAA"
     gene            14146..15483
                     /gene="adiC"
                     /locus_tag="OPY25_001012"
     CDS             14146..15483
                     /gene="adiC"
                     /locus_tag="OPY25_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HCS0926679.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLAATGGIAIY
                     GWLVTIIGALALSMVYAKMSSLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTLTCVAVLWIFVLLNIVGPKMITRVQAVATVLALV
                     PIVGIAVFGWFWFKGETYMAAWNVSGMNTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLLIVGVLM
                     TIFQFSSMSPNAAKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPLYLLITF
                     VAFVYCIWAVIGSGAKEVMWSFVTLMVITALYALNYNRIHKNPYPLDAPVKQD"
     gene            15617..17260
                     /gene="eptA"
                     /locus_tag="OPY25_001013"
     CDS             15617..17260
                     /gene="eptA"
                     /locus_tag="OPY25_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HCS0926680.1"
                     /translation="MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNS
                     LRNVLVFISMPVVAFSVVNSVLTLASFIWLNRLLACIFILVGAAAQYFILTYGIIIDR
                     SMIANMMDTTPAETFALMTPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLAS
                     VLISILLVILVAAFFYKDYASLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMLKGDRKNLTILIVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTT
                     SCGTATAISVPCMFSDMPRKHYDEELAHHQEGLLDIIQRAGINVLWNDNDGGCKGACD
                     RVPHQNVTELNLPGQCIDGECYDEVLFHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNR
                     YPPQFKKFTPTCDTNEIQNCSQQQLINTYDNTVLYVDYIVDKAINLLKSHQDKFTTSL
                     VYLSDHGESLGENGVYLHGLPYSIAPDTQKHVPMLIWLSKDYQQRYQVDQACLQKRAS
                     TLDYSQDNLFSTMLGLTGVQTTYYQAADDILQPCRRLSE"
     gene            17257..17925
                     /gene="pmrA"
                     /locus_tag="OPY25_001014"
     CDS             17257..17925
                     /gene="pmrA"
                     /locus_tag="OPY25_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PmrA"
                     /protein_id="HCS0926681.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGH
                     YSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTARDTLNDRISGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVA
                     TEES"
     gene            17935..19005
                     /gene="pmrB"
                     /locus_tag="OPY25_001015"
     CDS             17935..19005
                     /gene="pmrB"
                     /locus_tag="OPY25_001015"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HCS0926682.1"
                     /translation="MRFQRRAMTLRQRLTLTIGLILLVFQLISTFWLWHESTEQIQLF
                     EQALRDNRNNDRHIMHEIREAVASLIVPSVFMVSLTLLVCYQAVRRITRPLAELQKEL
                     EARTADNLTPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG
                     VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVI
                     LPSYDELNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHIT
                     IHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIVSRITQLHQG
                     QFFLQNRTERTGTRAWVLLKKA"
     gene            complement(19013..19102)
                     /gene="pmrR"
                     /locus_tag="OPY25_001016"
     CDS             complement(19013..19102)
                     /gene="pmrR"
                     /locus_tag="OPY25_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HCS0926683.1"
                     /translation="MKSYIYKSLTTLCSVLIVSSFIYVWVTTY"
     gene            complement(19172..20674)
                     /gene="proP"
                     /locus_tag="OPY25_001017"
     CDS             complement(19172..20674)
                     /gene="proP"
                     /locus_tag="OPY25_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HCS0926684.1"
                     /translation="MLKRKKIKPITLGDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMIAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYATIGIWAPILLLLCKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLEWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLLSCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVIMGSIA
                     LFALAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLIAGLTPTLAAWLVESSQDLMIPAYYLMVIAVIGLITGISMKETANRPLKGAT
                     PAASDIQEAKEILGEHYDNIEQKIDDIDQEIAELQVKRSRLVQQHPRIDE"
     gene            21142..21477
                     /locus_tag="OPY25_001018"
     CDS             21142..21477
                     /locus_tag="OPY25_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HCS0926685.1"
                     /translation="MSLPHCPQCNSEYTYEDNGMFICPECAHEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIVKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
     gene            21597..22040
                     /gene="yjdN"
                     /locus_tag="OPY25_001019"
     CDS             21597..22040
                     /gene="yjdN"
                     /locus_tag="OPY25_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HCS0926686.1"
                     /translation="MPLSPYLSFAGNCADAIAYYQQTLGAELLYKLSFGEMPPSAADN
                     EEGCPSGMRFPDTAIAHANMRIAGSDIMMSDASASGTAHYSGFTLVLDTQDVAEGKRW
                     FDNLAAQGQIEMDWQETFWAQGFGKVSDRFGVPWMINVVKHQPAT"
     gene            22192..22626
                     /gene="phnO"
                     /locus_tag="OPY25_001020"
     CDS             22192..22626
                     /gene="phnO"
                     /locus_tag="OPY25_001020"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HCS0926687.1"
                     /translation="MPVCELRHATTEDTDSVYALICELLKNELDYQAFRDGFAANLLD
                     PNLHYRLALRNGEVVGMISLHMQFHLHHANWIGEIQELVVLPQMRGQKVGSQLLAWAE
                     EEARQAGAELTELSTNIKRRDAHRFYLREGYKQSHFRFTKAL"
     gene            22884..23792
                     /gene="lpxO"
                     /locus_tag="OPY25_001021"
     CDS             22884..23792
                     /gene="lpxO"
                     /locus_tag="OPY25_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A hydroxylase LpxO"
                     /protein_id="HCS0926688.1"
                     /translation="MFAAIIIGIFIISVIYAHSRGVEKQKLSRQLFDHSTFMAPINMF
                     MTRFSTLPAKQPYFDTTAFPELQKLTENWQVIREEALRLQHHIKAAQANNDAGFNTFF
                     KRGWKRFYLKWYSDAHPSAETLCPITTKLVNSIPSIKAAMFAELPPGAYLGKHRDPYA
                     GSVRYHLGLSTPNDDRCFIEVDRQRHSWRDGEAVIFDETYVHWAENKTEQTRIILFCD
                     IERPMKWRWAQSVNHWVGASLMSAASSPNDENDRTGAINRIFKYVHAARDAGQRLKKK
                     NRTLYYALKYLVIAAIFAAIILFSLL"
     gene            24131..26278
                     /locus_tag="OPY25_001022"
     CDS             24131..26278
                     /locus_tag="OPY25_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:24548..24550,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase N subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HCS0926689.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLESVSWDEALNYVAERLSAIKAKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYSKIVEGYTPESVEEITGVSAQ
                     EIRQAARMYASAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPSAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKFPENREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQGIFMTKTASAADVILPSTSWGE
                     HEGVFSAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGYIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTEEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTADAARLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLRESAMG"
     gene            26455..27144
                     /locus_tag="OPY25_001023"
     CDS             26455..27144
                     /locus_tag="OPY25_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HCS0926690.1"
                     /translation="MKPLIALMLFMTFFAHAADPEPGSQYLQAAEAGDRRAQYFLADS
                     WLSYGDLNKAEYWAQKAADNGDADACALLAQIKITNPVSLDYPDAKKLAEKAANAGSK
                     AGEITLARILVNTQAGRPDYPKAISLLQKASEDLDNDSAVDAQMLLGLIYANGVGIAA
                     DDEKAAWYFKRSSAISRTGYSEYWAGMMFLNGEPGFIEKNKQKALHWLNLSCLEGFDT
                     GCEEFETLTNG"
     gene            complement(27302..28612)
                     /gene="gltP"
                     /locus_tag="OPY25_001024"
     CDS             complement(27302..28612)
                     /gene="gltP"
                     /locus_tag="OPY25_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HCS0926691.1"
                     /translation="MKNLKVSLAWQILLAMVLGILLGSYLHYHSDSREWLIANLLSPA
                     GDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIGAKTILYFELITTVAIILGITL
                     ANVFQPGSGIDMSQLATVDISKYQNTTAEVQSHAHGLMGTILSLVPTNIIASMAKGDM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFVLIAVT
                     VANFGFASLWPLAKLVLLVHFAIIFFALVVLGIVARLCGLSIWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYERDVLGKFDKTAQ"
     gene            complement(28957..29577)
                     /gene="nrfG"
                     /locus_tag="OPY25_001025"
     CDS             complement(28957..29577)
                     /gene="nrfG"
                     /locus_tag="OPY25_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HCS0926692.1"
                     /translation="MSQSEHSTVPLRPMPVKRLTAAAVLMVAVCIGGYMLTPKWQAVR
                     SEQQRLADPLRDFTNPQTPEAQLSRLQEKIRANPQDSEQWARLGEYYLYRNAYDNALL
                     AYRQALRLRGDNAQLFAALATVLYYQSGQHMTPATREMINKALALDATEVTAQMLLAA
                     DAFMQADYAQAVSLWQTLLDANSPRVNRAQLVEAINLAKLLQNRQK"
     gene            complement(29574..30083)
                     /gene="nrfF"
                     /locus_tag="OPY25_001026"
     CDS             complement(29574..30083)
                     /gene="nrfF"
                     /locus_tag="OPY25_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012134579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HCS0926693.1"
                     /translation="MRKLLTALPDGGVSALSGLQDAQTVGRISVAPSGRKFLLLTIVL
                     FLITFATHAQVVDTWRFDNPQQQEKALSIAGQLRCPQCQNQNLLESNAPVAVSMRHQV
                     YSMVAEGKSEAEITAWMTDRYGDFVRYNPPLNEQTLLLWALPCLLLLLVGVVVWRVRK
                     RQHAEEGEQ"
     gene            complement(30076..31812)
                     /locus_tag="OPY25_001027"
     CDS             complement(30076..31812)
                     /locus_tag="OPY25_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016507453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HCS0926694.1"
                     /translation="MHNLDIFLPEAGFLALLLSLGVNVLTPLATWCGMAQHWRGVMRL
                     TTCGAWTAFTLLLLAFAILFSCFLTSDFSVVYVAQHSHSQLSWGLKLAAVWGGHEGSL
                     LLWALLLSGWTVLFAWRSRHESDALFPLTLSILSLIMASLLLFIVLWSDPFLRIFPPA
                     MEGRDLNPMLQHLGLILHPPLLYLGYGGLMTAASVALASLLCGGFNAATAWVCWRWAL
                     LGWCALTLGIILGSWWAYCELGWGGWWFWDPVENASLLPWLAASALLHSLYVSRQRGS
                     FRHWSLLLAILTLILSLLGTLIVRSGILLSVHAFALDNVRAVPLFILFAALSLASLAL
                     YGWRAREPYPATRLGGGKCETLILATLLLFSAVLLIVLVGTLYPMIYGLMGWGRLSVG
                     APYFNRVTLPFGLLMLVVIVLATIRSRKVSVHRQLPALLAHTGVFIFAAGIMVSSGSR
                     HEISLNLSPGQQVVLAGYTFRFERLDLEAKGNYTSEKARITLWRNEKRIGSLQPERRF
                     YAARRQQMMEPGIHWNLLHDWYAVMGEKTGADRYAMRLYVQTGVRWIWGGGLLMVCGA
                     LLSGWRGRKRDA"
     gene            complement(31805..32761)
                     /gene="nrfD"
                     /locus_tag="OPY25_001028"
     CDS             complement(31805..32761)
                     /gene="nrfD"
                     /locus_tag="OPY25_001028"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HCS0926695.1"
                     /translation="MTSASAFHFASLVWDWPIAIYLFLIGISAGLVTLAILLRRFHPE
                     AGGSDSTLLRTTLVLGPGAIILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLILWLAKIFEKEVIALQQRWLPRLEIVQKVLTLIAPFHRALETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMALRHRSNPHSTEARFVH
                     RMEVPVVWLEIFLLAAFFVGLALGDDGKMRALAAALGGGFWSWWFWLGVVGLGLIIPM
                     LLKPWANRSVTFHGVLAVCGASLTGVLLLRFFILYAGQLTVA"
     gene            complement(32758..33429)
                     /gene="nrfC"
                     /locus_tag="OPY25_001029"
     CDS             complement(32758..33429)
                     /gene="nrfC"
                     /locus_tag="OPY25_001029"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HCS0926696.1"
                     /translation="MSCTRRQFITRVGALAAVSGMAGRVVANTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNNVPEGVSRLTIIRSEPQGTFPDVKYRFFRHSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVSKTADKCDFCRKTNL
                     KAGKQPACVESCLTKALTFGNLDDPNSDISRLLRQKTTYRYKLALGTKPKVYRVPFNY
                     GEVSQ"
     gene            complement(33426..33992)
                     /gene="nrfB"
                     /locus_tag="OPY25_001030"
     CDS             complement(33426..33992)
                     /gene="nrfB"
                     /locus_tag="OPY25_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HCS0926697.1"
                     /translation="MSVLRSLLTAGVLASGLFWSLSGITATPTPQESDQRWTVTQQRN
                     PDAACLDCHKPDTEGMHGKHTGAINPNNKLPITCTNCHGQPSLHHREGVKDVMRFNDP
                     MYTVEQQNSVCMSCHLPEQLQKAFWPHDVHVTKVTCASCHSLHPQQDTMQTLNEKGRI
                     KICVDCHSDQRTNPHFNPASVPLLKEQP"
     gene            complement(34104..35540)
                     /gene="nrfA"
                     /locus_tag="OPY25_001031"
     CDS             complement(34104..35540)
                     /gene="nrfA"
                     /locus_tag="OPY25_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HCS0926698.1"
                     /translation="MARKTLRARRFFSLIFPFFFITSVYAEQTPVSAKTVTVEAKNET
                     FAPQHPDQYQSWKATSEQSAREDALAEDPRLVILWAGYPFSRDYNKPRGHAYAVTDVR
                     ETLRTGAPKTAEDGPLPMACWSCKSPDVARLIQQEGEDGYFHGKWARGGPEIVNDLGC
                     ADCHNTASDDFAQGKPAITLSRPYAERAMEAIGKPFDKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDEGMKVENMEQYYDAIAFSDWTNSLSKTPMLKAQHPEYETWSAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKASLQKVVAERKQ
                     AIHDLKIKVEDQLVHAHFEAKAAWDAGATDAEMKPILNDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGSAMDKAADARTKLARLLATKGITHEIPLPDISTKEKAQKAIGLNMQQ
                     INAEKQDFLKTVVPQWEDQARKNGLLSQ"
     gene            35972..37930
                     /gene="acs"
                     /locus_tag="OPY25_001032"
     CDS             35972..37930
                     /gene="acs"
                     /locus_tag="OPY25_001032"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HCS0926699.1"
                     /translation="MSQTHKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGK
                     ILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAIAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVI
                     VLKRTGNDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVD
                     NEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            38169..38483
                     /locus_tag="OPY25_001033"
     CDS             38169..38483
                     /locus_tag="OPY25_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HCS0926700.1"
                     /translation="MNDQIYQRIEDSARFRELVEKRQRFATILSVIMLAVYISFILLI
                     AFAPGWLGTPLHAGTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNAVLHEVK
                     AL"
     gene            38480..40129
                     /gene="actP"
                     /locus_tag="OPY25_001034"
     CDS             38480..40129
                     /gene="actP"
                     /locus_tag="OPY25_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HCS0926701.1"
                     /translation="MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSLGLGLIFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAYKDAAG
                     ALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     RKGATEREELKVSKITVLVLDVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAF
                     LGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH"
     gene            complement(40168..40857)
                     /locus_tag="OPY25_001035"
     CDS             complement(40168..40857)
                     /locus_tag="OPY25_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCS0926702.1"
                     /translation="MNNVQLSVLCLVITLGIYFANKRLYRRFRKLPLMPLVLTPALLV
                     LMLVFGHISWQNYISESHWLLWLLGPATIAFAVPVYDNLAIIKRHWMSLTAGVVTATV
                     VAVTSSVWLARLFTLSDEIQRSLAVRSVTTPFALAAAEPLGGQPDLVALFVVVTGVFG
                     MAVGDALFLRLSIREGMAKGAGFGAASHGAGTARSYELGQQEGVVASLVMMLSGVVMV
                     LAAPLVARVMF"
     gene            complement(40850..41260)
                     /locus_tag="OPY25_001036"
     CDS             complement(40850..41260)
                     /locus_tag="OPY25_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCS0926703.1"
                     /translation="MAVAISRVTPAVVQRLQVPVQVLLYAGLFIFSQYLVSWLHLPLP
                     ANLVGMVLMLALIVCRIIPLSWVRAGARWLLAEMLLFFVPAVVAVVNYAHLLLVDGWR
                     IFSVIAISTLMVLGATAWVVDKVYRYEMSRLNRE"
     gene            41364..42251
                     /locus_tag="OPY25_001037"
     CDS             41364..42251
                     /locus_tag="OPY25_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0926704.1"
                     /translation="MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELN
                     CTLLIRDGRKLLLTDTGRVVFERGLAILAEFRQLEAELSDINHLNKGVLRLGIPPMVG
                     MLMAGPISLFRQRYPGVELKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSL
                     FSHPLCVLVPRSGQWTTCDSIAPEALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIA
                     VRSGQWDFLAAMVQAGVGIAILPEPICQRLDKATLRWLPLESDLRWQLGMIWREGVYL
                     SHSARAWLTCCEGFWLKQP"
     gene            complement(42346..43992)
                     /locus_tag="OPY25_001038"
     CDS             complement(42346..43992)
                     /locus_tag="OPY25_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HCS0926705.1"
                     /translation="MEIFFTILIMTLVVSLSGVFTRVLPFQLPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVLVTVVGIGF
                     LIYWLVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMVFTVGGATLEFFKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILESSLAAAEADPNVETWMLFTDIVLIYAALMLVRFGW
                     LWTMKKFSLRFLKKKPMEFASWTSREILIASFAGVRGAITLAGVLSIPLLLPDGSGFP
                     ARYELVFLAAGVILFSLFVGVIMLPLLLQHLEVADHAQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSIQEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLMEALLIENQ"
     gene            complement(44142..45491)
                     /gene="ghxP"
                     /locus_tag="OPY25_001039"
                     /gene_synonym="yjcD"
     CDS             complement(44142..45491)
                     /gene="ghxP"
                     /locus_tag="OPY25_001039"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HCS0926706.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGVGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTIISATGIRSWILRNLPQGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFDTFPVIMSLVGLAVILGLEKLKVPGGILLTIIGISIVGL
                     LFDPNVHFSGIFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDRDGQIIDGGKALTTDSLSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPVYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVVGRLVSGEWRKLNIGTVVIAVALVAFYAGGWAI"
     gene            complement(45838..46506)
                     /locus_tag="OPY25_001040"
     CDS             complement(45838..46506)
                     /locus_tag="OPY25_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HCS0926707.1"
                     /translation="MLTVHHLNQSRSQRILWALEELALPYQIVRYQREKTMLAPPALK
                     KVHPLGKSPVIEDHGMVIAESGAILEYLQDTYDNIGRFKPADAQRKQHYRFWLHYAEG
                     SLMPLLLMRLLFTSLGKPPVPLGLRTLGGVIGKGAQKAYLNPQLETHARFIDGHLANH
                     PWFAGEQLSMADIQMSFPLFALLARGGIAHLDHINAWKARVEMRPAWQRAIQQGGPFT
                     IPGG"
     gene            complement(46799..47257)
                     /gene="soxR"
                     /locus_tag="OPY25_001041"
     CDS             complement(46799..47257)
                     /gene="soxR"
                     /locus_tag="OPY25_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HCS0926708.1"
                     /translation="MEKKSPRLKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIGDAFGILPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEHGTGARLLEDD"
     gene            47344..47667
                     /gene="soxS"
                     /locus_tag="OPY25_001042"
     CDS             47344..47667
                     /gene="soxS"
                     /locus_tag="OPY25_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HCS0926709.1"
                     /translation="MSHQQIIQTLIEWIDEHINQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGEYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRREFDRTPSD
                     YRHRL"
     gene            complement(47655..49256)
                     /locus_tag="OPY25_001043"
     CDS             complement(47655..49256)
                     /locus_tag="OPY25_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCS0926710.1"
                     /translation="MSQSTRRKVLRFLGTIIVVLLPVLLAIWFAHIRAVSETRNQLHS
                     FAQLVLDKTERVILQADLARDAAEQYQGQACTPAHQQRMLNIIRGRLYINELIYAKGQ
                     RFLCSTVMTPTSPYFIPRADYKRKPDIAIYYYRDTPFFNGYKMTYMQRGNYVAVINPL
                     SYSEVMSDDPALAWGMYDTVTNTFFSLSEQAQADQLLPLVQRSEPVFQQGERFYALVK
                     SAKRPVAAIVSTSKQRFYQNLFHQLTLTLPLGIICSIIVLFMWSRSRQAYYSPRRLLQ
                     RAITRHQLCLHYQPIIDIRNGTCVGAEALLRWPGYHGPVMSPCEFIPLAEKEGMIEQI
                     TDYVVEEVFNDLGGFLAAHPHLYVSINLSAADFLSSRLIVMIHEKTRQHSVLAQQIKV
                     EVTERGFIDVPKMTPIIQAFRQAGYEVAIDDFGTGYSNLHNLYSLNVDLLKIDKSFVD
                     TLTTNSASHLIVEHIIEMAQSLRLKIIAEGVETAEQVSWLLKRGVQYCQGWHFAKALP
                     PQEFIVWLQQTPAPLTIRGQTPYRR"
     gene            49819..50100
                     /locus_tag="OPY25_001044"
     CDS             49819..50100
                     /locus_tag="OPY25_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HCS0926711.1"
                     /translation="MAAITTGVVLLRWQLLSAVLMFLASTLNIRFRKSDYIGLAVISS
                     GLGVVSACWFATGLLGITMMDLAAIWHNIEAVMVETMSQTPPEWPMVLT"
     gene            complement(50379..>51286)
                     /gene="siiF"
                     /locus_tag="OPY25_001045"
     CDS             complement(50379..>51286)
                     /gene="siiF"
                     /locus_tag="OPY25_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiF"
                     /protein_id="HCS0926712.1"
                     /translation="TIMVIAFFMVIKGDVTTGAIVSSVIVSGRISGIISNFSSTLISI
                     LSAEKTGKDLLSFFDEDQAEKTPALQSISKCNGDISIRGVSYQYDAQSPMIINRLSID
                     IPAGQRVAVIGECGAGKSSLLGMLSGYLSPTDGAILYDGYNLGHLSQNFFSQHLSVVT
                     THDVLFTGTIESNFALKPQNDRGRVLKALHLANCGFILQHPMGLKFPVNFMAKNLSSG
                     QQQQLLLARSLSSNASVFLWDEPTSNLDENTEKQIFDNLDEFIHGKTLIMVTHRRYLI
                     KYFDRVLVMKGGKIIRDCSPDKLLM"
BASE COUNT        12635 a        13898 c        13137 g        11616 t
ORIGIN      
        1 aggtagcgcc ccctgcaaga ctagacgggc ttttcaacac tggagcaaca tcgcctatgc
       61 ctttgaatta gacgcctcat cagggataat aaccttacga ttcgtccgct caggtccact
      121 atgaaacact ccctgccatg ccgggcgtta cgcaaacgcc ccatgaaact cggcactacc
      181 gtcattctga tggtcagcgc cgttttgttt tcggtgctcg ttgtggtcca tctgatctat
      241 ttttcgcaaa tcagcagcat gacgcgcgac gcgctggcag ataaagcgct ggcggtggct
      301 cgctcgctgg cggactctcc ggcaattcgc gaggggctga aaaaaccgcc tgcggaaagc
      361 ggcattcagc cgctctccga agcggtgagc cagcataatg gctttttgtt tattgtggtg
      421 accaatatgc agggcatccg ttattcgcac ccagaaacgc agcgaatcgg tcaaccgttc
      481 aaaggcgatg acattctgct cgcactgcag ggaaaggaaa acgttgccat taatcgcggc
      541 tttcttgcca aagcgctgcg cgttttcaca ccggtttatg atgaacacca ccgacagatc
      601 ggcgtggtag cgattggcct ggaactcagt cacgttacgc agcagatcaa caatagccgc
      661 ggcagtatta tctggtccat tctgttcggc gctctggtgg gattattagg cacctatgcg
      721 ctggtcaagg tgctaaaacg tatcctgttt ggcctcgaac cctatgagat ctcaaccctg
      781 tttgaacaac gccaggcgat gctgcagtca atcaaagagg gcgtaatcgc cgtagatgat
      841 agcggcgaag tcacgttgat taaccacgcg gcgcaggcgc tgctcgatta tcgaaaaaca
      901 caggatgacg ccagattatc caccctgagt catgcctggc cgcaggtggt ggacattagc
      961 gaagtgttgc gtgacggtac gccgcgccgc gatgaagaga ttatcgtcaa aggccgcctg
     1021 ctgctggtga ataccgttcc ggtgcgcagc aacggcgaaa ttatcggcgc gatatccacc
     1081 ttcagggata aaacagaagt tcgccaactg atgcagcggt tagacgggat ggtgaactac
     1141 gcggatgcgc tccgtgaacg atcccacgaa ttcatgaaca aattacatgt gattctggga
     1201 ttattgcacc tgaagagtta taagcagctt gaagcgtata ttatcaagac ggccaataac
     1261 tatcaggaag agatcggttt gctgctgggt aaaataaagt cgccgattat cgctggcttt
     1321 ttgctcagta agattacccg cgcctctgat ttcgggcaca gcctggtgat aagcagcgac
     1381 agccagttac cggataataa caatgaagat caggttacgg tgctgattac ggcgctgggt
     1441 aatttgattg aaaacgcgct ggaagcgttg agccaggaat ccggcggcga aatcagcgtc
     1501 tcgttacact accgtcatgg ctggctgcat tgcgaagtga gcgatgacgg tccgggtatc
     1561 gaacctgagc gcatcgaggc gatttttgaa aaaggcgtct cgtcgaaagg cgccgaacgc
     1621 ggcgtcggtt tagcgctggt taaacagcag gttgaagcgc ttggcggcgt aatttccgtg
     1681 gagtccgagc ctgggatctt cacacaattt tttgtacagt taccctggga tggaaaaagg
     1741 accagcctat gatcaatgta ttaattgtcg atgacgatgc gatggtcgcg gagttaaatc
     1801 gccgctatgt cgcgcaaatc tccggttttc attgttgtgg aaccgcttcg acgctggaaa
     1861 aagcgaaaga gtttatcttc aacagtgaaa atcacattga cctaatcctg ctggatatct
     1921 atatgcagca ggaaaacgga ttggatctgc tgcctgtcct gcacagcgca ggctgcaaaa
     1981 gcgacgttat tgtcatttct tctgccgctg acgccgccac cattaaagat tcgcttcact
     2041 acggcgtggt ggattatctg atcaagcctt ttcaggccac gcgctttgaa gaagcgttga
     2101 ccggctggct acgtaagaaa acggcgatgg aaaaacgcca gtattacgaa cagtctgagc
     2161 ttgacctgct cattcacggt aattcatcca gcgagcagga gcctcgtcgg ctgccaaaaa
     2221 ggctgaccca gcaaacgcta cgcaccttat gccagtggat tgatgcgcat caggagcagg
     2281 aattttctac cgacgagtta gccaacgaag tgaatatctc gcgcgtctcc tgccgtaaat
     2341 atctcatctg gctggtgaat tgccatatct tgtttaccag tattcattac ggcgtgaccg
     2401 gcaggccggt ttaccgctac cgcgttcagc cggaacatta ctctttactg aaacaatatt
     2461 gtcagtaagg ataccgcata aagccgacgc gaagcgttat atcttggtaa catttattat
     2521 aacaatgcca ataaaaacgc tatcacatta ataacaaacc tgggaaattg tgtcagatca
     2581 aatatactca acccaggcct gttaacgtta ttttctatta ttacagcgct atgcgctgtt
     2641 tttaatttca aaacgataac aaaagttaat taagtattat cccatgccga gagtgtgtat
     2701 ttttattaaa aaagggattt gtccggaatt ttcctgacac ttaaataaaa ttatgtttgt
     2761 agcaatggag cttgtgctac gcctatggac aatacgtata ttggtgagca gatacgcgtc
     2821 tccacacgcc atactaataa tttaaaaaaa tggcgtgaca atgatcacat aagtcacatt
     2881 ctgttcaatt tatctcgtga tttacctgat ggcgagacac aaaaattaaa taataaacgc
     2941 ctgtttttaa aacagacaaa tcataattta ctgctctcgc tgactccacc tgcccatcgc
     3001 cagagggtgc ttccctctga acatcaccat cgcaagaaaa taattactta aagcaactct
     3061 gtaaaaagct taatcgttaa tcgtcgccac tgacgcattg aatattcgcc atttcctgat
     3121 gctcattcac acaaatcaga agatggctgt gatccattta tcaaaattga ctgggtttat
     3181 cgcgaggata aataaaaatg ttatttagta tacagcttct cataatatta atatgtctgt
     3241 tttatggtgc ccgaaagggc gggatcgcgc tcgggttgtt gggcggtatc ggtctggtca
     3301 ttctggtgtt tgttttccat ctccagccag gtaaaccgcc cgttgacgta atgctggtca
     3361 ttatcgcggt agtcgccgcg tcggcgacgt tgcaggcgtc aggcgggctg gatgtgatgt
     3421 tgcagattgc cgaaaagctg ctgcgccgca accccaaata cgtctctatt gtggcgccgt
     3481 tcgtcacctg taccctgacg attctgtgtg ggacaggcca cgtggtttac accattttgc
     3541 cgattatcta tgacgtggcg atcaagaata atatccgtcc ggaacgtcca atggcggcca
     3601 gttctatcgg cgcgcaaatg ggtatcatcg ccagtccggt ttccgtcgcc gtggtttctc
     3661 tggtagcgat gctgggcaac gtgacatttg acggaaaaca tctggagttc ctcgatctgc
     3721 tgtcgatcac catcccgtct accctgctcg gtatcctggc aatcggtatt tttagttggt
     3781 tccgcggtaa agatctggat aaagacgaag cgtttcagaa atttatctcc gtaccggaaa
     3841 accgtcagta cgtgtacggc gataccgcga cgctgctgga taaaaaactg ccgaaaagca
     3901 actggctggc gatgtggatc ttcctggcgg cgattgccgt ggtcgctctc ctgggcgcgg
     3961 actccgactt acgtccaacc ttcggcggca aaccgttgtt gatggtgctg gtcattcaga
     4021 tgttcatgct gctgaccggg gcactcatta tcattctgac caaaaccaat cctgcgtcta
     4081 tctcaaaaaa cgaagttttt cgttccggta tgattgcgat tgtcgcggta tacgggatcg
     4141 cctggatggc ggaaaccatg ttcggcgcgc atatgtcgga aattcagggc gtgctgggcg
     4201 aaatggtcaa agagtatccg tgggcctacg ccatcgttct gctgctggtc tccaagtttg
     4261 ttaactccca agcagcggcg ctggcggcga ttgttcccgt cgcgctggct atcggtgtcg
     4321 atccggcgta tatcgtggcc tctgcgccgg catgttatgg ctactatatc ctgccgacct
     4381 acccaagcga tctggcggcg attcagtttg accgttccgg cacaacccgt attggtcgct
     4441 tcgtcattaa ccacagcttc attctgccgg gtttgattgg cgtgagcgtc tcctgcgtct
     4501 ttggctggat ctttgccgca atgtacggat tcctgtaatg gccgcgcgcg ccgcccggct
     4561 atgcgcggcg cgcgacttag agcctggccc atgaggctct taatacattt tcttactatt
     4621 aggctggaag cacatgtcga aaaaagagtt tatctatcag gcgcctttcc cgatgggaga
     4681 ggacaaaaca gagtattatc tgctcacctc cgattatgtc agcgtcagtg aattcaatgg
     4741 agaatctatc ctcaacgttg agccgcaggc gttaacgttg ctggctcagc aggctttcca
     4801 tgatgcgtct tttatgctcc gtcctgaaca ccagcagcaa gtcgccgcca ttctccatga
     4861 ccccgaagcc agcgaaaacg acaaatatgt ggcgttgcaa ttcctgagaa actccgagat
     4921 cgccgccaaa ggcattctgc cgacctgcca ggataccggc acggcgatta tcatgggtaa
     4981 aaaaggccaa cgcgtctgga cgggcggcgg cgatgaagcc gcgctctcca aaggcgtgtt
     5041 taatacctat atcgaagata acctgcgcta ctcgcagaac gcgccgctgg atatgtacaa
     5101 agaggtcaat accggcagca acctgccagc gcaaatcgat ctctatgccg tcgatggcga
     5161 cgagtacaag ttcctttgcg tggcgaaagg cggcggttca gcaaacaaaa cgtatctcta
     5221 tcaggagacc aaagcgctgc tcaccccagg caagctgaaa aacttcctcg ttgagaaaat
     5281 gcgcacgctg ggcaccgcgg cctgtccgcc ataccatatc gcctttgtca ttggtggcac
     5341 ctcggcggaa agcacgctga aaaccgttaa actcgccagc acccactatt acgacgcgct
     5401 gccgacggaa ggtaacgagc acggccaggc attccgcgat ctccacctgg aacaggaact
     5461 gctggaagaa gcgcaaaaac ttggcctcgg cgcccagttc ggcgggaaat atttcgccca
     5521 cgatattcgc gtaattcgcc tgccgcgtca cggcgcttcc tgtccggtgg ggatgggcgt
     5581 ctcctgctcg gcagaccgta acatcaaagc gaaaatcaac cgcgaaggca tctggatcga
     5641 aaaactggaa cacaatccgg gccagtatat tccgccagcg ctgcgtcagg cgggcgaagg
     5701 cgacgcggtg aaagtcgatc ttaaccgtcc gatgaaagag atcctcgccc agctatcgca
     5761 gtacccggtc tcgactcgcc tgtcgctgac gggcaccatt atcgtaggtc gcgatatcgc
     5821 ccacgcgaag ctaaaagagc gtattgaatc cggcgaagac ctgccgcagt atattaaaga
     5881 ccaccccatc tattacgcag gtccggccaa aaccccggca ggttatccat ctggctcatt
     5941 aggccccacc accgcaggcc gaatggactc ttatgtcgat ctactgcaat cccacggcgg
     6001 cagtatgatc atgctggcga aaggcaaccg tagtcagcag gtcacggatg cctgtaaaaa
     6061 acacggcggc ttttatttgg gcagtatcgg cggcccggcg gcggtactgg cacagcagag
     6121 cattaagcat ctggagtgcg tcgagtatcc ggaactcggc atggaagcta tctggaaaat
     6181 tgaagtagaa gatttcccgg cctttattct ggtggatgac aaaggcaacg atttcttcca
     6241 gcagattgtc agcaaacagt gcgctaactg cgcgaaataa cctggcaggc ccggcgttct
     6301 cccgggccgc gttatcggtt aattgccgga tggcgctacg cttatccggc ttatccggcc
     6361 tgcacgagag accatgctca cgcttttaca tcgctggtcg ctaccacaga aatcgccggg
     6421 ctatccggct gttcgacgaa tggcggcgtt ttccggtatt tatccagcag gtggatctga
     6481 atcttgcgca gcatatcgcc gttcaaacgg tagtagcgga agtagagaac caacgtcatc
     6541 atgaaaaaca gtaccggcag gacaatcata ataaactgca tcccctgcag ggtttgcgca
     6601 gactgcgcca cgttcggcgt gtagccaatc agccccagca ccagagcgat aaagaacgcc
     6661 gcaaacgccg agccgccctt cacaaccatc gtctgtacgg aataagcgat actctcgcag
     6721 cgaatattga gcttaaattc cccataatcg accgtatccg ccaccatgat tacctgaagc
     6781 acccaaaaga gcgcggtccc gatattcagg aaaatacccg ccgccacgat taaagcggca
     6841 ttatggacat ccgccaacgc catcgcgaag agccctgcgc aactcagaac gggcatcacg
     6901 gaggcgcccg cccacaatat ccgccgcgat aacattttca ccagccgggg gaagacaatc
     6961 agcgtcagca gattcgccgc gccggcgtaa gaaaggtaat agggaaaaag atcggcatcg
     7021 ccaatcacat aggtgaagta gtagatcgca aagctattga taatattgga ggcgatgtta
     7081 tacgccagcg ccattcccaa caggcaagag agctgatcgt ttttgtatat caatccaacg
     7141 atcgttttta acgtcagatg tgggcggccc gccgttacac cgttgtcgga ggagtacacc
     7201 tcatgtacgt tgcgtaatgt cacgatagtc gaggcgataa agaacgcaat cagtaccagc
     7261 gtaaacatct gaaagccgaa cccacgatcc gccccgccaa catagttcac aaacggcagc
     7321 gttataccgg cagtgacgaa gccagccaga ctggcgaaga aacgcgggaa cggcaccagt
     7381 tgttcgcgtt ctcgcttatc aagcgtaatg gtcggcacca gcgaccaaaa tgggatatcc
     7441 ataatggtat acgtcatgcc ccacaggatg taggttacgc agacaaatac aacctgcgcg
     7501 gttccctcaa aaagatgggc gctgaacagc aggaaaagca ccagcgaatt ggttaaggtg
     7561 ccgatcaata tccacggctt aaatttcccc caccgcgaac gcgtggcgtt gacaatccag
     7621 cccatgatgg gatcgtttat cgcatcccaa attcgcgcga ccagaaagag ggtgccgacg
     7681 aggccgaccg agagtcccac cacatcggtg tagtaataca tcaggtacat atacacaatg
     7741 ccgatggcga aatccttacc aaacgcaccg aacccgtaac tcagctttgt tgtcagagag
     7801 atgctcatag ggtaccgggt cgctgttacc agcgcccgcc ttctgttagt agaggttaaa
     7861 cgccggatct gccgtccagc gcggctggag attaacggcg taaccaggcc ggaagccagt
     7921 cgccatgcgc ggcgatcaga tcgtcaacca acgcatagat ttcttcgata cccagcaccg
     7981 ccgcggtatg agggtccatc atcgccgcgt gatacacgcg atcgcggttt tccgtgagga
     8041 tggcttcggt caacagcgtt tgcacgttga tgttggtctg catcattgcc gccagatggg
     8101 aagggatcgt ccccaccttc gtcggttgaa tgccgttggc atctaccaga caagccacct
     8161 cgacgcagct tccctgcggc aggttatcaa tcagtccctc attacgcaca ttgccgtaaa
     8221 tcacgctcgg ctcgccggtc cacagagcgt tcataatggt gctggcgtac tcgcgggacg
     8281 gtttgatgtc gatacgctcg gcggttttat actcctccag ctctttatgc cagttcgcca
     8341 gttgttctac gcagcgtttc ggatattcat ccagcggcac cttgtagcgc gcaatcagat
     8401 cctcgcgtcc cggtttaata aaccacggcg tgtactcggc aaaatgctct gatgactccg
     8461 tgacgaagta gcccaacttt ttgaacatct catagcgcac gatgttctgg cagcgttcat
     8521 tgccgtgaat attgggcttc ggcgcctgtc cggcgtcata agccgccagc aattcaggat
     8581 agagattgac ataagtcccg tcagccgttt tgcgctccag ttccaggtaa aacgccatgt
     8641 ggttaatgcc gacgcagcgg tagcgcagcg aggcgggatc gatattcaag tcgcgcgcca
     8701 gttcttccgc cgttccctgt accgaatggc acaggccgac ctgtttgata tgcggatagc
     8761 gggcatacat cgcccaggta ttcatcgcca tcgggttgac gtaattgagc atggtggcct
     8821 tcggacagac ttccgtcatg tcttcgcaaa tctgccacag atgcgggatg gttcgcagcg
     8881 cgcgcatgat gccgcccggc cccagcgtat cggcgatcgt ctgttccagg ccatgacgct
     8941 tacaaacctc aaaatcggtc acggtgcagg gttcatagcc gccaatctga aaggcgacca
     9001 ccacgaaatc cgcatcctgt agcgccgctt tctggtgggt atggcaggta atccggccag
     9061 aagcgcccgc tgagtccatc agtttccgta ccacaatgtg cgactcttcc agccgggttt
     9121 cgtcaatatc catcagggcg acatgcgctg actttagcgc ctcgcggtga aacacatcgc
     9181 cgaggatatt tttgacgaaa atcgtagaac ctgcgccgat aaaggtaatt ttgggtgccg
     9241 tcatcatgac tctccagaac agtagtgaac accttcatgg tggcacgcgt tcccggtgaa
     9301 aacctccgtc ttccccgatg agcattcccg aaaactcaga tcgtatgctg gcgcgcggga
     9361 gatctgagtt tttgggacaa aatggcgtaa aaagcagagt attcggcctg atagtcaggc
     9421 tacgctctac aatatcgacg gattctgtgt ccggattccc ggtttcctcc cggctaaagg
     9481 ggcataattc tgataattca ggaaatggag tgacgatgag tacgcaagca atatccctcc
     9541 tcccgcccga cccgcacatg tgcaacggcg atgaaaagca aacccgtagc ccgctgtcgc
     9601 tctattccga atatcaacga ctggacgttg agctgaggcc gccgcacaga atggccagca
     9661 gtcactggca tgggcaagta gaagtgaatg ttccgtttga cggcgatgtg gagtatttaa
     9721 tcaacaatga agtcgtgcag ataaagcagg gacatatcac cctgttttgg gcctgtacgc
     9781 cacaccagct tacccgcccc ggcaactgcc gccagatggc gattttcagt ttgccgatgc
     9841 acctgtttct ctcctggccg ctggatcgcg atcttatcaa ccatgtcacg cacgggatgg
     9901 tggttaaatc actggcgacc cagcagctta gcacctttga agtgttgcgc tggcagcagg
     9961 aaacaagcag cccgaatgag caaattcgcc agttggcgat cgatgaaatc ggcttgatgc
    10021 ttaaacgctt tagcctttcc ggctggcaac ccattttgct caataaaaca tcacgcaccc
    10081 acaagaatag cgtctcacgc catgcgcagt tttacgtaag ccagatgctg ggatttattg
    10141 ccgataacta cgatcaggcg ctaaccatta acgacgttgc ggagcatgtc aaactcaatg
    10201 ctaactacgc gatgggaata ttccagcggg ttatgcaatt gacgatgaag cagtacatca
    10261 cggcgatgcg catcaatcac gtacgtgcct tattgagcga tactgacaaa acgatcctcg
    10321 atgtcgctct gactgccggg ttccgatcca gcagccgttt ttacagtact tttagcaaat
    10381 ttgtcggtat gtcgccgcaa caataccgca agctaagcca gcaacgacgc cagacgatgc
    10441 ccggctaaag ccggatacca ctatcagcca aaaaaataat tcacctgtcg ataaacggcg
    10501 ggtgaaattg ctcgctatca ataattaacc cattgtttat taaacaataa tatcaataac
    10561 tgaccattat tccatcactt tacaccccct atttgacggg gtaatacttg cccacgtcac
    10621 attcatacgg cgggtcggca aggcgtaaat tgcacggcct ccacaaccgg gtaaaagatg
    10681 atgaaagtat taattgttga aagtgagttt ctgcatcagg acacctgggt tggcaacgcg
    10741 gttgagcgtc tggcggatgc cttgagccaa caaaatgtta ccgtcattaa atcgacatcc
    10801 ttcgatgacg gctatgccat cttgtccgcg aacgaagcca ttgactgtct gatgtttagc
    10861 taccaaatgg aacaaccgga tgagcacctg agcgtcaggc aattgatcgg taagcttcac
    10921 gagcgtcagc aaaacgtgcc cgttttcctg ttaggcgaca gggaaaaagc gacggcatcg
    10981 ctggaccgcg acctgctgga gcttgtcgat gaattcgcct ggattctgga agacaccgct
    11041 gactttatcg ccggacgcgc cgttgccgcc atgacccggt atcgccagca actgttaccg
    11101 ccgctgttta acgcgttgat gaaatacagc gacattcatg aatattcatg ggcggcgccg
    11161 ggacaccaag gcggcgtcgg tttcactaaa acgcctgccg gtcgctttta tcacgattat
    11221 tatggcgaaa acctgttccg cagcgatatg gggattgagc gtaccacgct cggttcactc
    11281 ctcgaccata ccggcgcgtt tggcgaaagc gagaaaaacg ccgcccgcgt attcggtgct
    11341 gaccgctcct ggtccgtggt tgtcgggacc tcaggttcta accgtactat tatgcaggcc
    11401 tgtatgacgg ataatgatgt cgttgtactg gatcgtaact gccataaatc catcgaacag
    11461 gggctgatcc tcactggggc caaaccggta tatatggtgc caagccgtaa ccgttacggc
    11521 attatcgggc caatctaccc gcaggaaatg cagcctgaaa ccttgcagaa aaaaatcagc
    11581 gccagcccgc tgaccaaaac caaagccgga cagaaaccgt cttacagcgt ggtgaccaac
    11641 tgtacctatg acggcgtatg ctataacgcc aaagaggcgc aggatctgct ggcaaaaacc
    11701 agcgatcgca ttcacttcga cgaagcatgg tacggctatg cgcgcttcaa cccgatttat
    11761 tgcgatcact acgcgatgcg cggcgagcca ggcgaccata acggtccgac cgtgtttgcc
    11821 acccactcca cgcacaaatt actgaacgcg ctttcacaag cttcctacat tcacgtccgt
    11881 gaaggccgtg gcgcggtgaa tttctcccgc ttcaaccagg cctatatgat gcatgccacc
    11941 acctctccgt tatatgccat ctgcgcatcc aacgatgtgg cggtatcgat gatggacggt
    12001 aacagcggcc tgtccctgac tcaagaggtg attgacgaag cggttgattt ccgtcaggcg
    12061 atggcgcgtc tttataaaga gtttaccgat gaaggcgact ggttctttaa accgtggaat
    12121 aaagacgtcg tcaccgatcc acaaaccggt aaaacgtatg acttcgccga cgcgccggca
    12181 aaactgctgg caaccgacca gaactgctgg gtcatgcgcc ccggggaaac ctggcacggc
    12241 tttaaagacc tgccggataa ctggagtatg ctggacccga ttaaagtcag tatcctggcg
    12301 ccgggtatgg gcgacgatgg cgaactggaa gcatccggcg tacctgctgc gctggtcaca
    12361 gcatggcttg gccgccacgg tatcgtgccg acccgcacca ccgacttcca gattatgttc
    12421 ctgttctcca tgggggtaac tcgcgggaaa tggggaacgc tgatcaacac gctgtgctcc
    12481 ttcaaacatc attacgacgc gaatacgccg ctggcgcagg tgatgccgga actggtgcag
    12541 gattatcctg acacttacgc gaacatgggt attcatgacc tgggcgataa aatgtttgcc
    12601 tggctacgtg aaaataaccc gggcgcccgt ctcaatgccg cctattccac cctgccggtt
    12661 gcggagatta ccccgcgcga cgcctacaac gcgatcgtga acaacaatat tgaaatggtg
    12721 gcgattgaaa atctaccggg tcgcattgcg gcgaactccg ttattcctta cccgccaggc
    12781 atcccgatgc tgctctccgg tgaaaacttt ggcgatgaaa acagtccgca ggtgggttac
    12841 ttacgctcac tgcaatcctg ggatcatcac ttccctggct ttgagcatga aaccgaaggc
    12901 acggaaatta ttgatggcgt atatcacgtt atgtgcgtga aagcctaatc acaaagagtc
    12961 tttttttgag gatggcatgt attccctgag tattgctgca aaacaataat actgtcatac
    13021 ctttttgcgc gggccccatc ccgcgctttt tttatacaaa aatgacaagt ttccactcgc
    13081 gtacaacttt ttgtacaccc taattcatcg tacaaatatt gtaatattat tcaggaaagc
    13141 tattttaatg cagtttcaat tcatcacaca attgattcag tccccgttat ctctcccgtt
    13201 tggcgagatc cggtctttta tgttcatatt ccaggagttc gggtatgagg atttgcagca
    13261 acgagccttg catagtgtta ttaaccgaaa aagatacatg gttacgagta aatggtaagg
    13321 agccaatcag tttaaaagcg aatcatatgg ccattctggc ttgtgaaaat aacgttattg
    13381 acatttcatc attaaatagc gtgctagtaa tacaagtgag tcgcaataat attaaagact
    13441 atttacaatt cctgaataaa gatctctcac accttcccgt ctggcaacgc aacgccgatc
    13501 ccttattgac cgccacctgt ctgacgccgg atatcttcag ggtcgccgcc cgctacagcg
    13561 cgatggaaac accggatgaa attgttagtg aacgcacccg tgcgctcctt ttcaccgttt
    13621 tatcccgctt tcttgaccac aaaaaattta tttctttgtt aatgcacatg ctgcgcagcc
    13681 gcatcagtga cagcgtttac cacatcattc agagcgatat tcataaagac tggaatctga
    13741 gcgccgttgc cagctgcctg tgcctgagtc caagcttgtt aaagaaaaag ctcaaaaacg
    13801 agaataccag ttatagccaa ataatcacga cctgccgaat gcgttatgcc gtaaaccaat
    13861 tattaatgga cggaaagaat atctcgcaag tctcacagct ttgtgggtat aacagcacgt
    13921 cgtactttat ttccgtgttt aaagagtttt atggtatgac ccccctgcat tatgttagcc
    13981 aacatcggga acgatcggct gcctaatttt tctacactca acgataagac acgataataa
    14041 cagcattggc gataacccgt ctccgatata attcagcggc attctgaggg ggtatgatac
    14101 gacgtaattt atcgtaacga agtcaccttt tcaggagtcc aaattatgtc ttcggatgct
    14161 gatgctcaca aagtgggcct aatccccgtc accttaatgg tatcggggaa tattatgggt
    14221 tcaggggtat tcttactccc tgccaacctg gcggccactg gcgggattgc aatctacgga
    14281 tggctggtca ctatcatcgg cgccctggcg ctgtcgatgg tttatgccaa aatgtcgtcc
    14341 ttagatccca gtcccggcgg ttcttatgcc tatgcacgcc gctgcttcgg gccgtttttg
    14401 ggctatcaaa cgaacgtgct gtactggctg gcatgctgga tcggtaatat cgcgatggtc
    14461 gttatcggcg tcggctatct gagctatttc ttcccgattc tgaaagatcc gctggtatta
    14521 acgcttacct gcgtcgcggt gctgtggatt tttgttctgc tgaacatcgt cgggccgaaa
    14581 atgattaccc gcgtacaggc cgtcgccacc gtactggcgc tggtgcctat cgtagggatt
    14641 gcggtcttcg gctggttctg gtttaaaggc gaaacctata tggcggcctg gaacgtgagc
    14701 ggtatgaata ccttcggcgc gattcaaagc acgttgaacg tcacgctatg gtcattcatc
    14761 ggggtagaaa gcgcctccgt tgcggccggt gtggtaaaaa acccgaaacg caacgtgcct
    14821 atcgccacca tcggcggggt actgatcgcc gccgtctgct atgtactctc cacaacggcg
    14881 attatgggga tgatccccaa cgcggcgctc cgtgtgtcag catcgccttt cggtgacgcg
    14941 gcgcgtatgg cgctgggcga taccgcaggg gctattgttt ccttctgtgc ggcagcgggg
    15001 tgcctgggct ctctcggcgg ctggacgctg cttgccggcc aaaccgcaaa agcggcggcg
    15061 gacgatggtc tcttcccgcc gatcttcgcg cgggttaata aagccggtac gccagtggct
    15121 gggttgctta tcgtcggcgt gctgatgact atcttccagt tcagcagtat gtcgccgaac
    15181 gccgcgaaag agtttggtct ggtctcctcc gtgtcggtta tcttcaccct ggtgccttat
    15241 ctttacacct gtgccgcgct gttgctattg ggccacggtc actttggtaa agcgcgcccg
    15301 ctgtatctgc tgattacctt cgtcgcgttt gtatattgca tctgggcggt tatcggttcc
    15361 ggcgccaaag aagtgatgtg gtcgttcgtc acgttgatgg tgatcaccgc gctgtatgcg
    15421 ttgaactaca accgcattca caaaaacccg tatccgctgg atgcgccggt taaacaagat
    15481 tgaccacgtg tagttaatgt tatcgcaaca ggccggatag cgcaggttat ccggccacca
    15541 ccaacattaa gttcttaagg ttcacttaat tttactttgt cacgattagc gtcaccgaat
    15601 cgatggacgc atcaacatgt taaagcgctt tcttaaaaga cctgttcttg ggcaaatcgc
    15661 ctggcttctg cttttttcct tttatattgc cgtctgcctg aacattgcgt tctacaagca
    15721 ggtactacaa gacctaccgt taaactcgct gcgcaatgtg ctggtgttta tttccatgcc
    15781 ggtcgtcgcg tttagcgtgg tcaatagtgt gctgacgctg gcctcattta tttggctaaa
    15841 ccgactgctg gcctgcattt ttattctggt cggcgctgcc gcgcagtatt ttattttgac
    15901 ttacggcatc atcatcgatc gctccatgat cgccaatatg atggatacca cgcccgcgga
    15961 aacttttgct ctgatgacgc cgcaaatggt gctgacgctg ggattaagcg gcgttctggc
    16021 agccgtgatt gccttctggg tcaaaatccg tccggcgacg ccgcgcttac ggagcgggct
    16081 ttaccgcctg gccagcgtcc tgatctctat tttattagtt attctggtcg ccgccttttt
    16141 ctataaagat tacgcctcgc tatttcgaaa taataaacag ttgatcaaag cgttaagccc
    16201 atcgaacagt attgtcgcca gttggtcatg gtattcgcat caacggctgg cgaatttgcc
    16261 gctggtacgc attggcgagg atgcccatcg caatccatta atgctgaaag gcgatcgcaa
    16321 aaacctgacg attctcatcg ttggcgaaac ctcgcgcggc gatgatttct ctcttggcgg
    16381 ctatccgcgc gacaccaatc cgcggctggc gaaagacgat gtgatctact tcccgcatac
    16441 cacctcttgc ggtacggcga ccgcgatctc cgttccctgc atgttttctg atatgccgcg
    16501 caaacattat gacgaagagc tggcgcatca ccaggaaggg ctactggata ttatccagcg
    16561 cgcggggatt aacgtactgt ggaatgataa tgacggcggc tgtaaaggcg catgcgatcg
    16621 cgttccgcat caaaatgtca ccgagctaaa cctgcccgga caatgtatcg acggcgagtg
    16681 ctacgatgaa gtgttatttc acggtctgga agactatatc gaccatttga aaggcgatgg
    16741 cgttattgta ctgcatacca tcggcagcca cggcccaacc tattacaacc gttatccacc
    16801 gcagtttaaa aaatttaccc caacctgtga cactaacgaa attcagaact gttcccaaca
    16861 gcagttgatc aacacctatg ataataccgt gctgtacgtg gactatattg tagataaagc
    16921 cattaacctg ctgaaatctc accaggataa attcaccacc agcctggtct atctttccga
    16981 tcacggcgaa tcattgggtg aaaatggcgt ttatttacac ggtttgccgt attccattgc
    17041 gccggatacg caaaaacatg tcccgatgct catttggctt tctaaagatt atcaacagcg
    17101 ttatcaggtg gatcaggcct gcctgcaaaa acgggcgagc acgctggatt attcacagga
    17161 caatcttttc tcaaccatgc tgggattaac cggcgtacaa acgacgtatt accaggccgc
    17221 agatgatatt ctgcaaccgt gcaggagact aagcgaatga agatactgat tgttgaagac
    17281 gacacgctat tattacaggg gttaatactc gccgcgcaaa ccgaaggcta tgcgtgtgat
    17341 ggcgtttcga cagcgcgtgc cgccgagcat agtctggagt ctggtcatta cagtctgatg
    17401 gtgctggatt tagggctgcc cgatgaggat ggcctgcatt tcctgacgcg aatccgacag
    17461 aaaaaataca ccctgccggt actcattctg accgcccgcg atacgctcaa cgaccgcatt
    17521 agcgggctgg atgtcggcgc agatgattat ctggtaaaac ccttcgccct ggaggagctg
    17581 cacgcccgca tccgcgcgtt gctgcgccgc cataataacc agggtgaaag tgaactgacg
    17641 gttggcaatc tgacgctcaa tataggccgc catcaggcat ggagggatgg acaggaactg
    17701 accctgacgc ctaaggagta cgcgctgctc tcacgattga tgctcaaggc aggcagtccg
    17761 gtgcaccggg aaattcttta taacgatatc tacaactggg ataacgaacc ctcgaccaac
    17821 actctggaag tgcatataca taatttgcgc gacaaagtcg gcaagtcgcg cattcgcacg
    17881 gttcgcaggt ttggctacat gctggttgcc actgaggaaa gctaagtgag cctgatgcgt
    17941 tttcagcgaa gagcgatgac ccttcgccag cgtttaacgc tgacaattgg tcttattctg
    18001 ctggtgttcc agctaatcag taccttctgg ttatggcatg aaagcactga gcaaatccaa
    18061 ctgttcgagc aggcgctgcg ggataatcgc aacaacgatc gccatatcat gcacgaaatt
    18121 cgcgaggcgg tcgccagcct gatcgtcccc agcgtattta tggttagcct gacgctgctg
    18181 gtttgctacc aggcggtacg gcgtattacc cgcccactcg ccgaactgca aaaagagctg
    18241 gaagcgcgga cggcggataa tctgacgccg atcgccattc acagctccac gcttgagatt
    18301 gagtccgtcg tctcggcgat caatcaactg gttacgcgtt tgaccaccac gctcgacaat
    18361 gaacgccttt ttaccgccga tgtggcccat gagctacgca cgccgctgtc gggggtgcgt
    18421 ttgcatctgg aattattgtc aaaaacccac aatgttgatg tcgcgccgct tatcgcccgt
    18481 cttgaccaga tgatggatag cgtctcccag cttctgcaac tggcgcgcgt gggccagtca
    18541 ttctcttccg ggaattatca ggaagtaaaa ctgctggaag atgtgatcct cccctcctac
    18601 gatgagctga acaccatgct ggaaacgcgc cagcaaactc tgttgctgcc ggaaagcgcg
    18661 gcggacgtgg tggtgcgcgg tgacgcgacg ttactgcgta tgctgctgcg aaatctggtg
    18721 gaaaacgcgc atcgctatag ccctgaagga acccatatca ctatccacat tagcgccgac
    18781 cccgacgcta ttatggcggt cgaagacgag gggccgggta ttgatgaaag caaatgcggg
    18841 aagctaagcg aagcgttcgt gcggatggac agccgttatg gcggaattgg cctggggctg
    18901 agtatcgtca gccgcatcac ccagctacat cagggacagt ttttcctgca aaaccgtacg
    18961 gaaagaacag gcacccgtgc ctgggtgctg ttgaaaaagg cataacaggc gtttaatacg
    19021 tcgtgaccca cacatagata aaactgctga caatcagcac actacacagg gtcgtcaaac
    19081 ttttataaat atagcttttc atgacgctct cctccaaagg tatggaggag agtatgcccg
    19141 cgagagatta agcgaacctt aagcgcgaaa tttattcatc gatacgcgga tgttgctgta
    19201 ccagacgcga acgtttgacc tgcagctccg caatttcctg atcgatgtcg tcgattttct
    19261 gctcaatatt atcgtaatgc tcgcccagaa tttccttcgc ttcctggatg tccgacgccg
    19321 ctggcgttgc gccttttaac ggacgattgg ccgtctcttt catggaaata ccggtaatca
    19381 agcctatcac cgcgatgacc atcaaataat acgccggtat catcagatcc tgcgagcttt
    19441 ccaccagcca ggccgccagc gttggcgtca gaccggcaat caatacagag atattaaaag
    19501 ccgccgccag cgcgctgtaa cgaatatgcg tcggaaacat cgccggcaat gtcgaggcca
    19561 tcaccccggt aaagcagttc agaatcaccg ccagcatcaa caaaccggca aaaatcaggc
    19621 caataacgtt actgttaatc aggatgaagg ccgggatcgc cagcgcgaac agcgcaatgc
    19681 tgcccataat cacaaatgga cgtcgaccga aacggtcgct cagcagcccc atcaccggct
    19741 gcacaaacag catcccgatc ataatggcga tgataatcaa cacgccgtga tcttcagaat
    19801 agtgcaggtt atgcgacagg tagctcggca tgtaggtgag cagcatgtag taggtcacgt
    19861 tggtggcaat caccagaccg atacatgaca acaggctacg ccagtgtttg gtggcaatct
    19921 ctttaaagga gactttcggc ccatcctgca acccttcgcg gtcgccctgc tccagtttat
    19981 ccacgtgctg ctgaaacgct ggcgtctcct ccagcgcatg gcgtaagtag agaccaataa
    20041 tccccaatgg cagggcgata aagaacggaa tacgccagcc ccactcaagg aaattctcct
    20101 cgccgacaat cgtcgagatt aagaccacca cgcccgcgcc cagcacgaac ccggcgatgg
    20161 aaccaaaatc cagccagctt cccataaatc cgcgtttacg atccggcgaa tattccgcga
    20221 caaagatcga cgcgccggta tattccccgc caaccgagaa gccctgcgcc attttacaca
    20281 gcaacaacag tattggcgcc cagataccga tcgtcgcgta agaggggatt aacccgatac
    20341 agaaggtact gatcgacata atcacaatcg tgatcgccag gatcttctgg cgcccgtatt
    20401 tatcgccgag cataccaaag aataacccgc cgagcggacg aatcaggaag ggaacggaaa
    20461 acgtggccag cgcggcaatc atctggacgc tgggatcggc gccggggaaa aagactttac
    20521 ccaacgcgta ggcaacaaat ccataaacac caaaatcaaa ccactccatc gcgttgccca
    20581 gcgacgcggc ggtaatcgct ttgcgaagtt taccatcatc aatgatggtc acatcgccca
    20641 gtgtaatcgg ttttattttt ttccttttca gcatagctgt cctcataggc taagccctgt
    20701 agcgctatat acggcgggca ctggcatacc gcgccagcgt cgccgtcgag cggagggagg
    20761 ggcgcgaacg ctatccctca tacaagcgta gcaggtttac ttacactgtc cggttacgga
    20821 ctgtacaacc gaacctgttg acgcctgaat gggcagttaa tgaccttttt accctaacag
    20881 ggtttaaata tgtgatcaac ttcacacata tatgtcaatt tggtcaaaag gtgtaaacaa
    20941 ggacgcccta atgcgctgta gtggcagtaa aaaagcggtt attcgagtgt aaaccattgc
    21001 tgactggcgt ggcgcagccc cttttataaa agcggcaata gtcccgacaa cactaaggat
    21061 tttgtgtata attgcggcct ttttcggcga tctgccattt ttgggcgcgt ttgcccccgc
    21121 tgactttttg aggataccaa catgtcatta ccccactgcc cgcaatgtaa ctccgaatat
    21181 acctacgaag ataacggcat gttcatctgc ccggaatgcg ctcacgaatg gaacgatgcg
    21241 gaacccgctc aggagagcga tgagctgatt gtcaaagacg ccaacggcaa cctgctggcg
    21301 gacggcgata gcgtcaccat cgtgaaagat ctgaaagtaa aaggcagctc ttccatgctg
    21361 aaaatcggca ccaaagtgaa gaacattcgt ctggttgaag gcgaccataa catcgactgc
    21421 aaaatcgatg gttttggccc gatgaaactg aaatccgagt tcgtgaaaaa gaactgattt
    21481 accgtatcat tgcccggtag cgccttgctt accgggcctg agcggccctg ccaccgacaa
    21541 tattgtgcca atttcgaact acacttaacg agcatctctt acctgaggta accatcatgc
    21601 cgttaagtcc ctatctctct tttgccggca actgtgccga cgccatcgcg tattatcaac
    21661 aaacgttagg cgcagaactg ctttataaac tcagcttcgg tgaaatgccc ccctcggcgg
    21721 cggataatga agagggctgc ccgtcaggaa tgcgctttcc cgatactgct atcgcccacg
    21781 ccaacatgcg cattgcgggc agcgatatca tgatgagtga tgccagcgcg tcgggaacgg
    21841 cgcattattc cggctttacg ctggtgcttg atacccagga tgtagcagaa gggaagcgct
    21901 ggtttgataa ccttgccgca caagggcaaa tcgaaatgga ctggcaggag actttctggg
    21961 cgcagggttt cggcaaggtc agcgatcgtt tcggtgtgcc gtggatgatt aacgtggtta
    22021 aacatcagcc tgccacctaa ctccccggga ggctcgcctt cccccttgcc atcagagtga
    22081 tctttggctg cacgttatcc gccgtttagc tgccatagaa taaataatga cggtagtttg
    22141 ctacagtctg gcgaaagatg gttgatcctg atgaagcgtc gggaggacat tatgccagtc
    22201 tgtgaattac gccacgcgac aacagaggat accgattctg tttacgcgct tatctgtgag
    22261 ttacttaaaa atgagcttga ttatcaggct ttcagggatg ggttcgccgc taatttactg
    22321 gaccccaacc ttcattatcg tttagcgcta cgcaacggag aggtggtcgg catgatcagc
    22381 ctgcatatgc agtttcatct ccatcatgcc aactggattg gcgaaattca ggagctggtg
    22441 gtattaccgc agatgcgggg acaaaaagtt ggcagtcagc ttctggcctg ggcagaagaa
    22501 gaagcacgtc aggcgggtgc ggagctaacg gagctttcca caaatattaa acgccgcgat
    22561 gcacaccgtt tttatcttcg cgaaggttac aagcaaagtc atttccggtt tacgaaagca
    22621 ttgtgatctg gcaaccgtca tcaggagata aggcataacg taatcagccg tcaccgggtg
    22681 aagtagcgga gtcatctcaa ttctactgtc gacaagcctg gataaaggtt aaacgggctg
    22741 actcgcttct ttaacaaaaa tggccctttt aagttgtaga aatgtaaatt tattgtcaac
    22801 gaactacact tttctctttg gcatcaccgg gagggttgcc tgaaaatccc gggatgaggt
    22861 tttcttagaa ggacagtgac gttatgttcg cagcaatcat tatcggtatt tttattatca
    22921 gcgtcattta tgcgcattca cgcggggtgg aaaaacaaaa actttcccgt cagctctttg
    22981 accactcgac gtttatggcg ccgatcaata tgttcatgac tcgcttctca acgttaccgg
    23041 caaagcagcc gtactttgat accacggcat ttccagagct gcagaagctg acggaaaact
    23101 ggcaggtgat tcgtgaagag gcgctacggc ttcagcatca cataaaagcc gcgcaggcca
    23161 ataacgacgc cggattcaac acctttttca agcgcggctg gaaacggttt tatcttaaat
    23221 ggtattccga tgcccacccg tcggcagaaa cgttatgccc gataacgaca aagctggtca
    23281 acagcatccc ctctatcaaa gcggcgatgt tcgccgagtt gcctcccggg gcctatctgg
    23341 gaaaacatcg cgacccctat gccggttcag tacgttacca tcttggatta agcacaccga
    23401 atgatgaccg ctgttttatt gaagttgatc gacagcgcca tagctggcgc gacggcgaag
    23461 ccgtcatctt cgacgaaacc tacgttcatt gggcggaaaa taaaactgag cagacgcgta
    23521 ttatcctctt ttgcgatatt gagcgcccaa tgaaatggcg ctgggcgcag agcgtaaacc
    23581 actgggtcgg cgcatcgttg atgtccgccg ccagttcgcc aaacgacgag aacgatcgca
    23641 ccggtgcgat taatcgcatc tttaaatacg ttcacgcagc acgcgatgcc gggcaacggc
    23701 tgaaaaagaa aaaccgtact ctctattacg cgctgaaata tctcgttatt gccgctattt
    23761 ttgccgcgat aatccttttc agcctcctct gaagccgggc cacggtatga aactgcctgc
    23821 cgcggcctgt tctatcctgg cgttagtctc aaagcgttcc ctgaccttga gtctatccat
    23881 ccggataata tccacttcag gcagagcgtt ccgccttatc tggcctgcgc tccgcgtttc
    23941 tccccataat aaatgtcatg cggcattttc tttcgacacg tcaaaactga cgatagcctg
    24001 tttttcgtca gggttttgag caaaattcgc ccgtaatatc agggaaagcc catactaaaa
    24061 aagtggcata aaacatgcat actgagggcg acagcgcgta tgcgcgattt gattaactgg
    24121 agcgaaaccg atgaaaaaag tcgtcacggt ttgcccgtat tgcgcatcag gttgcaaaat
    24181 caatctggtg gtcgataacg gcaaaatcgt ccgggctgag gcggcgcagg ggaaaaccaa
    24241 ccagggtacc ctgtgtctga agggctacta tggctgggat tttattaatg atacccagat
    24301 cctgaccccg cgtctgaaaa ccccaatgat ccgtcgccag cgtggcggca aactggaatc
    24361 tgtttcctgg gatgaagcgc tcaattacgt cgctgaacgt ttgagcgcca tcaaagcgaa
    24421 gtacggtccg gatgcaatcc agacaaccgg ctcctctcgc ggtaccggaa atgaaaccaa
    24481 ctatgtaatg caaaaattcg cacgcgccgt tattggtacc aataacgttg actgctgcgc
    24541 tcgcgtctga cacggcccat cggttgcagg tctgcaccaa tcggtcggta acggcgcaat
    24601 gagtaatgcg attaacgaaa ttgataacac tgatttagtg ttcgtcttcg ggtataaccc
    24661 ggcggattcc caccctatcg tggcgaatca tgtgattaac gctaaacgca acggggcgaa
    24721 aattatcgtc tgcgatccgc gcaaaattga aactgcgcgc atcgctgaca tgcatatcgc
    24781 gttgaaaaac ggctcgaata tcgcgctgct caacgccatg ggacatgtca ttattgaaga
    24841 aaacctgtac gacaaagcgt ttgtcgccag ccgtaccgaa ggttttgaag agtacagtaa
    24901 gattgtcgaa ggctatacgc cggagtccgt tgaagagatc actggcgtga gcgcacagga
    24961 gattcgtcag gcggcgcgga tgtatgccag cgcgaaaagc gcggcgatct tgtggggtat
    25021 gggcgtcacc cagttctatc agggtgtgga aaccgtgcgt tcactgacca gcctcgcgat
    25081 gctgaccggt aacctcggca agccaagcgc gggcgttaac ccggttcgcg gccagaacaa
    25141 cgttcagggc gcgtgcgata tgggcgcgct gccggatact tatccgggct accagtacgt
    25201 taaattcccg gaaaaccgcg agaagttcgc taaagcctgg ggcgtagaaa gtctgcctgc
    25261 acataccggc tatcgcatca gcgagctgcc gcaccgtgcg gcgcatggcg aagtgcgcgc
    25321 ggcgtacatt atgggtgaag atccgctgca aaccgatgcg gagctctctg cggtacgtaa
    25381 agcgtttgag gacctggaac tggtcatcgt gcagggcatc ttcatgacca aaaccgcgtc
    25441 ggcggcggat gtgattttac cctccacctc ctggggcgag catgaaggcg tcttctctgc
    25501 ggctgaccgt ggcttccagc gcttctttaa agccgttgag ccgaagtggg acctgaaaac
    25561 cgactggcag attatcagtg aaatcgccac ccggatgggc tatccgatgc actacaacaa
    25621 cacccaggag atctgggatg agttgcgtca tctgtgcccg gatttctacg gcgccactta
    25681 cgagaaaatg ggcgaactgg gctatatcca gtggccatgc cgcgacacgt cggatgccga
    25741 tcagggaacc tcgtacctct ttaaagagaa gttcgatacc cccaacggtc tggcgcagtt
    25801 cttcacctgc gactgggtag cgcctatcga taaactcacc gaagagtacc cgatggtact
    25861 gtcgacggtg cgcgaagtcg gccactactc ctgccgctca atgaccggta actgtgcggc
    25921 gctggccgcg ctggccgatg aaccgggcta tgcgcaaatc aataccgccg acgccgcgcg
    25981 tctgggcatt gaagatgaag cgctggtgtg ggttcattcg cgtaaaggca aaatcatcac
    26041 ccgcgcgcag gtcagcgatc gcccgaacaa aggggcgatt tacatgacct accagtggtg
    26101 gattggcgcc tgtaacgagc tggtgactga aaacctcagc ccgattacca aaacgccgga
    26161 gtacaaatac tgcgccgtac gcgttgagcc gatcgccgat cagcgagccg ccgagcagta
    26221 tgtgattgat gagtacaaca agctgaaaac ccgcctgcgc gaaagcgcaa tgggttgatc
    26281 tgccggatgg cggcatcaga atgctttatt cggcctgcgt ctactgtagg cctgataata
    26341 tgcattagca tcgccatcag gcattttccc tataacagcc tccgcccgga ggctgttttt
    26401 ttatccatac gatctcttta tactgtcttt tccgtaccct aaataaaatt caaaatgaaa
    26461 ccacttattg cattgatgtt gtttatgaca ttctttgccc atgccgcaga tcctgagccg
    26521 ggtagccagt atttgcaggc agcagaggca ggtgacagac gcgcgcaata ttttctggcc
    26581 gacagttggt tgagctatgg cgatttgaac aaagctgaat actgggcgca aaaagccgcc
    26641 gacaatggcg acgccgacgc ctgcgcgcta ctggcgcaaa tcaaaatcac taatccggta
    26701 agcctggatt atcccgacgc gaaaaagctg gctgaaaagg cggctaacgc gggcagtaaa
    26761 gcgggagaaa ttacgctggc gcggatcctg gtcaacaccc aggccgggcg tccggactac
    26821 ccaaaagcca tctcgctgct gcaaaaggcc tctgaagatc tggataacga ctccgcggtg
    26881 gatgcgcaaa tgttgcttgg cctgatttac gccaacggcg tgggcattgc cgccgatgat
    26941 gaaaaagccg cctggtattt caaacgcagt tccgctattt cccgtaccgg ctattcagaa
    27001 tactgggcgg gaatgatgtt tttaaacggt gaaccgggct ttattgaaaa gaacaagcag
    27061 aaggcgttgc attggttgaa tctaagctgt ctggaagggt ttgataccgg ttgcgaagag
    27121 ttcgaaacgc taacaaatgg ctgatgttta ttgcctgatg aacgtagtcg ttgtaggcct
    27181 gataagcgta gcgccatcag gcaacccgga gccggttgtc ggatggcggc gtgaacgcct
    27241 tatccggcct acattctctt tctctgtagg ccggataagc aaagcgccat ccggcaatcc
    27301 gttattgggc ggtcttatca aatttgccca gtacgtcgcg ctcataggcc agcgcttttt
    27361 tacggtcaaa cttgtgttcc cacttggcga taaccagcac cgccagcgca ttccccacca
    27421 catttagcgc agtacgcgcc atgtcgagga tacggtcgac accggcgata aacgccagcc
    27481 cttccagcgg aatgcccacg ctgcccagcg tcgccagtaa caccacgaag gaaacgccag
    27541 gcacgccggc aatccctttc gacgtcacca tcagcgtcag caccagtaca atttcctgcc
    27601 acagcgacag gtcgataccg tatagctgcg cgataaaaat ggcggcgatg ctctggtata
    27661 acgtggagcc gtcgaggtta aatgagtaac cggtcggcac cacgaaactg gtgatagagg
    27721 ctggcgcgcc gtaagcttcc atcttctcga taatgcgcgg tagcacgctc tcggagctgg
    27781 cggtcgagta cgccagaatc aattcatctt tcagaatgcg aatcagaatc cagatactta
    27841 acccgcacag gcgcgccacg atgcccagca ccaccagcgc aaagaagata atggcaaagt
    27901 gtaccagcag caccagtttc gccagcggcc acagcgacgc gaaaccaaaa ttcgctaccg
    27961 tgacggcgat cagcacaaaa acgcccactg gcgcatagcg catcaccata tgggtgactt
    28021 taaacatggt ttcagagatg gaacgaaata ccgtcaccag cggttcgcgg tgcgttgccg
    28081 gcagggatga caaccccagc ccaaacagga ccgagaaaaa gataattggc agcatatccc
    28141 ctttggccat cgatgcgatg atattggtcg gcaccagcga cagtatcgtc cccatcagcc
    28201 catgtgcatg actttgtact tccgccgtgg tgttctggta tttcgaaata tcgacggtcg
    28261 ccagttgcga catatcaatg cctgagcctg gctgaaagac attcgccagc gtaatgccga
    28321 ggataatcgc caccgtggtg atcagttcaa aatagagaat ggttttggcg ccgatacggc
    28381 ctagctgttt tgcatcgcca acgccggcga tgccgacaat cagagtcgag atcacgattg
    28441 gcacgacgat cattttaatc agatggataa agatatcgcc agcaggcgac agcagattgg
    28501 caatcagcca ttcacggctg tcactgtgat aatgcagata gctgcccagc agaatgccca
    28561 gcaccatagc cagcaaaatt tgccaggcca ggctgacttt caaatttttc ataacaacag
    28621 acttcctcga tgaagcgttg ctctccgccg aaagcatgag agcaatacat actggaaggg
    28681 tatgatttgt gttgcgttgg tttgtagagt tttttaacgc gcataatcag tatcatttgc
    28741 atagcgtctt gcgcaaccct ttcataacag ggcttttggc tgtttttatg cataataacg
    28801 cgagtttatg gtgttaatga tgaataacta tttgttatgg aaagtttttt acttcgtcaa
    28861 aatcgaataa tattctgagg taattaattt ttacctgtgg cgcattcgcc gtttttttaa
    28921 acagcacaca tgacaaaagt cacaaaaaag aaaaaattat ttctgccgat tttgtaacaa
    28981 tttagccaaa ttaatggcct ctaccagctg cgcgcggttc actcgcggcg agtttgcatc
    29041 cagtaaggtt tgccacagcg acacggcttg cgcataatcc gcctgcataa acgcatccgc
    29101 cgccagcagc atctgcgcgg tcacttctgt cgcatccagc gctaacgctt tattaatcat
    29161 ttcacgcgtc gcaggcgtca tatgttgccc ggactggtaa tacagcaccg ttgccagcgc
    29221 ggcgaaaagc tgcgcgttat cgcctcgcag acgcaacgcc tgacgatatg ccagcagcgc
    29281 attgtcatac gcattgcgat agagataata ctcgcccagc cgcgcccatt gctcgctatc
    29341 ctgcggattg gcgcggattt tttcttgcag cctggaaagc tgcgcctctg gcgtttgcgg
    29401 gttcgtaaag tcacgtagcg gatcggccag acgctgttgc tcgctacgca cagcctgcca
    29461 tttcggcgtc aacatatagc cgccgataca gacagccacc atcaacaccg ccgcagccgt
    29521 cagacgcttt acgggcatgg gacgtaacgg cacagtggag tgctcagact ggctcattgt
    29581 tccccctctt ctgcgtgctg acgctttctc acccgccaga ccaccacgcc caccaacaat
    29641 aacagcaggc acggcagcgc ccacaacagc agcgtttgct cattcaacgg cgggttgtag
    29701 cgcacgaaat caccataacg gtcggtcatc caggcggtga tttccgcttc gcttttacct
    29761 tcggccacca tgctgtaaac ctgatggcgc atactgaccg ccacgggcgc attggattcc
    29821 agcaaattct ggttctgaca ctgcggacag cgcagttgac cggcaataga cagcgctttt
    29881 tcctgctgtt gtggattgtc aaagcgccag gtatccacca cctgggcgtg ggtggcgaat
    29941 gtgattaaaa acaggacgat cgttaagagt aaaaactttc tgccggatgg cgctacgcta
    30001 atccggccta cggtttgcgc atcctgtagg ccggataagg cgcttacgcc gccatccggc
    30061 aacgctgtga gtaatttacg catcacgctt cctcccccgc catccgctca gcagcgcgcc
    30121 acacaccatc aacaatcccc ctccccagat ccagcgcacg ccggtctgca cgtataagcg
    30181 catggcgtaa cggtccgctc cggttttttc gcccatcacc gcgtaccagt catgtagcag
    30241 gttccagtga atccccggct ccatcatctg ttgacgacgc gcggcataga agcgcctttc
    30301 aggctgcagg ctgccaatgc gtttttcatt ccgccacaac gtgatccgcg ctttttcact
    30361 ggtgtagttg cctttggctt ccagatccag acgctcgaaa cgaaaggtat agcccgccag
    30421 taccacctgc tgccccgggc tgaggttaag gctgatttca tgccgactgc cgctggaaac
    30481 catgatcccg gcggcgaaga taaatacgcc cgtatgcgcc agcaacgccg gaagctgacg
    30541 atgcacagag actttgcggc ttctgattgt cgcaagcacg ataaccacca gcatcagcag
    30601 gccaaacggc agcgtgacgc gattaaaata gggcgcgccc accgaaagcc ttccccagcc
    30661 catcaaacca taaatcatgg ggtagagcgt cccgaccagc acgatcaaca agacggcgct
    30721 aaagagcagc agcgtcgcca gaatgagcgt ttcgcacttt ccgccgccca aacgcgtcgc
    30781 cggatacggc tcccgtgccc gccagccgta cagagcaagc gatgccagac ttaacgcggc
    30841 aaaaaggata aacagcggca ccgcgcgcac attatctaac gcaaaagcat ggacggagag
    30901 cagaatgccg gaacgcacaa tcagcgttcc cagcaacgag aggatcagcg tcagtatcgc
    30961 cagcagcaac gaccagtggc ggaagctccc gcgctggcgg ctgacataca gactgtgcag
    31021 caacgcgctg gcggcaagcc acggcaacaa tgaggcattt tccaccgggt cccagaacca
    31081 ccagccgccc cagcccagtt cgcaatacgc ccaccacgat ccgagaatga tccccagcgt
    31141 cagagcgcac cagccgagta acgcccagcg ccagcacacc caggcggttg ccgcgttaaa
    31201 gccgccgcac agtagcgagg ccagcgctac gctcgccgcg gtcatcaggc cgccataacc
    31261 cagatagagc agcggcggat gtaagatcag ccccagatgt tgcagcatgg gattaaggtc
    31321 gcgcccttcc atggcgggag ggaaaatacg caggaacgga tcggaccaca gcacaataaa
    31381 tagcagcagc gaagccataa tgagggacaa gatgctcagg gtcagcggaa aaagcgcgtc
    31441 agattcatgc cgggagcgcc aggcgaatag caccgtccac cccgaaagaa gcagcgccca
    31501 cagcaggagc gagccttcat gaccgcccca taccgccgcc agtttcagtc cccatgacaa
    31561 ctgactatgg ctatgctgcg caacataaac gaccgaaaaa tcgctggtca gaaaacagct
    31621 aaacagaatc gcaaacgcca gtagcagcag cgtgaacgcc gtccacgcgc cgcaggtcgt
    31681 caggcgcatg acgccacgcc aatgctgcgc catcccgcac cacgtcgcca gcggggttaa
    31741 cacgttgacc ccgagactca acaacagcgc cagaaatccg gcttcaggaa ggaagatgtc
    31801 cagattatgc aaccgttagc tgtcccgcat aaagaatgaa aaagcgcagc agcagcacgc
    31861 cggtcaaact ggcgccgcaa acggccagca cgccgtgaaa cgtgacgctg cggttggccc
    31921 agggttttag cagcatcggg ataatcaatc ccagccctac gacgccaagc cagaaccacc
    31981 agctccagaa tccgccgccc agcgccgccg ccagcgcccg cattttgccg tcatcgccca
    32041 gcgccagacc gacgaagaac gccgccagca ggaaaatttc cagccatacc accggaacct
    32101 ccatgcgatg cacaaagcgc gcttccgtgc tgtgcgggtt gctacgatgg cgtaacgcca
    32161 tggcgatcag cgccaccgcc gcgccggagg aaatcccgga gaacaggaat agtaccggca
    32221 ggatcgggtt attcaggaac ggataggatt tcagcgccga cagcagaaag ccggtgtacg
    32281 cgccgagcag aaccgccagc accagcatta acgtctccag cgcacggtgg aacggcgcga
    32341 tcagcgtcaa cactttctgc acgatctcta accgcggcag ccaacgttgc tgcagggcaa
    32401 tcacctcttt ttcaaagatt ttcgccagcc acagtatcag gaccaccatg taaagctgga
    32461 acagcatcac ccccatcgac atcaccgagg taaagctgta gtgaaacatc agcttccaga
    32521 aggtccacgg gcgcgtcagg tggaagacca gaatcagcag accaagaata atcgcccccg
    32581 gccctaacac cagcgtagtg cgcagcagcg tgctgtccga accgcccgcc tccggatgga
    32641 agcggcgtag cagaatcgcc aacgtaacca gtccggcgga gatgccaatc aggaacagat
    32701 agatggcgat gggccagtcc cacaccagtg atgcaaaatg aaatgcagaa gcggatgtca
    32761 ttggctcacc tccccatagt taaagggaac gcggtagacc ttcggttttg tgcccagcgc
    32821 cagcttgtaa cgataggtgg ttttctgccg caacaaacgg gagatatcgc tgttgggatc
    32881 gtccagatta ccaaacgtca gcgccttcgt tagacatgac tcaacgcagg cgggctgttt
    32941 gcccgctttc aggttagttt tccggcagaa atcgcactta tccgccgtct tactgaccgg
    33001 atggataaag cgcacgcggt agggacacgc ggcaatgcag tactgacagc cgacgcaaag
    33061 gtccgggttc acgtcgacaa taccactggc ggcatcgcgg aatgatgcgc cggtcgggca
    33121 gacgtcaacg cagggggcat ggtcgcaatg ctggcacgag tggcggaaga agcgatattt
    33181 cacatcagga aacgtcccct gcggctcgct gcgaataatc gtcaggcgcg atacgccttc
    33241 cggcacgttg ttgacttccc gacaggcatc catgcaggcc gtgcagccga tgcataatga
    33301 ctcatcgtgt accatgccat aacgcacgcc gttaatattc aacgtgttcg ctacaacgcg
    33361 tcctgccatc ccactgaccg ccgccagcgc gccgacgcgg gtaataaatt gacgtcgggt
    33421 gcaactcatg gctgctcctt aagcaacgga acggacgccg ggttaaagtg cgggttagta
    33481 cgctgatcgc tgtggcaatc cacgcatatt ttgatccgcc ctttctcgtt tagcgtctgc
    33541 atcgtgtctt gctgcggatg cagggaatgg caactggcgc aggtcacttt agtaacatga
    33601 acatcgtgcg gccagaacgc tttttgcagt tgttcaggca agtggcagga catacagacg
    33661 ctgttctgct gctctaccgt atacatcggg tcgttaaaac gcatcacatc tttcacccct
    33721 tcacggtggt gaagcgacgg ttgaccgtgg cagttggtac aggttatcgg caatttattg
    33781 ttcgggttga tagcgcccgt atgtttaccg tgcatacctt cggtgtccgg cttgtgacag
    33841 tccagacagg cagcatccgg attacgctgc tgggtgaccg tccagcgttg atccgactcc
    33901 tgcggcgttg gcgtggcagt aattccactc aggctccaga acaggcctga tgccagcacc
    33961 ccagcagtta ataacgaacg taatacgctc atattcactc cattacataa tgcctgatgg
    34021 cgcgcagctt taaggcctac aagacttctg taggccggat aaagcgcttg cgctgtcatc
    34081 cggcaaattt gtcacatgtg aggttattgg cttaacagac cgtttttacg cgcctgatct
    34141 tcccactgcg gtacgaccgt tttcaggaag tcctgcttct ccgcgttgat ttgttgcata
    34201 ttcaaaccaa tcgctttctg cgccttctct ttcgtcgaaa tatccggcag cggaatttca
    34261 tgggtaatgc ctttggtcgc cagcagtcgc gccagtttag ttcgggcatc cgcggcttta
    34321 tccatcgcac tgcctaacat ccgtagacct tcttccgggg catgcatatg aataccgtgt
    34381 gacgcaatcg ccagatccca acgccactgc gcgtggcgaa tatcgttcag aatcggtttc
    34441 atttccgcgt ctgtcgcccc cgcatcccat gcggctttcg cttcgaagtg cgcatgtacc
    34501 agctgatctt caaccttgat tttcaggtca tgaatcgcct gtttacgctc ggcgaccact
    34561 ttttgcaggg acgctttgtc ctgggtgtgg cagttggcgc aggtttgcgc gaaattgtcg
    34621 aacgggttgc cgattttatg gtcggtgtag agcttgcctt cggcgttctg tactttcggc
    34681 atgtggcagt cgatacaggt cacgttgttc ttaccgtgaa tgcccgcgct ccaggtttca
    34741 tattccgggt gctgcgcttt gagcattggg gttttcgaca gcgagttagt ccagtcagag
    34801 aaggcgatgg cgtcgtagta ttgctccata ttttcgacct tcatgccctc atcccacggg
    34861 aacttaacgg ctttgttctt accgtcgaag tagtactcca cgtggcactg gccgcagacc
    34921 atcgattgct gatcaaatcg tcccgcttta tcaaacggtt tgccgatagc ctccatcgcc
    34981 cgttcggcat aggggcgcga caacgttatc gctggcttcc cctgggcgaa atcgtccgac
    35041 gcggtgttat gacagtcggc acagcccaaa tcgttgacaa tttccgggcc gccgcgcgcc
    35101 catttgccat ggaagtagcc gtcttcgcct tcttgttgga taaggcgcgc gacatcgggg
    35161 cttttacagc tccagcaggc catcggcagc gggccgtctt ccgccgtttt tggcgcgccg
    35221 gtacgcagcg tttcgcgcac gtcggttacc gcatacgcgt ggccgcgtgg tttgttgtaa
    35281 tcacgggaga agggatagcc cgcccacagg atcaccagac gagggtcttc cgccagcgca
    35341 tcttcacggg cagactgttc tgacgtcgct ttccatgact gatattggtc ggggtgttga
    35401 ggcgcgaacg tttcattttt cgcttcaaca gtaacggttt ttgcggatac aggcgtttgc
    35461 tcagcgtaaa cagaggtaat gaagaaaaaa ggaaatataa ggctgaagaa acggcgtgcg
    35521 cgtagtgttt tccttgccat agaggtctca tccagattgc gccattatct ttaatggcga
    35581 ttttttatcg ttttccataa cagcaaccgc acaaatactg ttattacatt gatctcctct
    35641 atgtgtaaca aataaccaca ctcaaaatgt tgtctttaat caattgtaag tgtatgtaaa
    35701 ataccacttt agagttagta acctggacaa aactccctct cttttctgat ttccggacac
    35761 ggatcacttt tttaaaaaat ttcatataac gtcatgttat cccgaaaatt tatctaattt
    35821 tgcgggacac aatcaaaaaa tagattgctg cttatttgca cagctccctt tttgcgtgat
    35881 ctgtcgccca aatactaaac aaaacttatt aagaccctac atttaacgtt tatgcgacat
    35941 attattaaca tcctacaagg agaacaacag catgagccaa acacataaac acgccattcc
    36001 cgccaacatt gcggatcgtt gcctgataaa tccagagcag tatgagacta aatataaaca
    36061 gtctattaac gaccccgata cgttttgggg cgaacaggga aaaattctcg attggatcac
    36121 gccgtaccaa aaagtgaaaa acacctcctt tgcgccaggc aatgtgtcga ttaaatggta
    36181 cgaggacggc acgctgaatc tggcggcgaa ctgtcttgac cgccatttgc aggaaaatgg
    36241 cgatcgcacc gccattatct gggaaggcga tgacgcgtcg cagagtaaac atatctctta
    36301 tcgcgaactg catcgcgatg tctgccgttt cgcgaataca ctgctggatc tgggcattaa
    36361 aaaaggcgat gtggtagcga tttatatgcc gatggtgccg gaagcggcgg tggcaatgtt
    36421 ggcctgcgcc cgcatcggtg cggtgcattc ggtgatcttc gggggcttct cgccggaagc
    36481 catcgccgga cgcattatcg actccagctc gcggctggtg atcaccgctg acgaaggtgt
    36541 acgtgccgga cgcagtatcc cgctgaaaaa gaatgtcgat gacgcgctga aaaacccgaa
    36601 tgtcactagc gttgagcatg tgatcgtcct gaagcgcacc ggcaacgaca ttgactggca
    36661 agaaggccgc gacctgtggt ggcgcgattt gattgaaaaa gccagccctg agcaccagcc
    36721 tgaagcgatg aatgccgaag atccgctgtt tatcctttat acctccggct ccaccggcaa
    36781 gccgaaaggc gtgctgcaca ccaccggcgg ctatctggtc tacgccgcga ccacctttaa
    36841 gtatgtcttt gattatcacc ctggcgatat ttactggtgt accgccgatg tgggttgggt
    36901 gacggggcac agctatctgt tgtatggccc gctggcctgc ggcgcgacca ccttaatgtt
    36961 tgaaggcgtg ccgaattggc caacgcccgc tcgcatgtgc caggtggtcg acaaacacca
    37021 ggtcaacatt ctctataccg ccccgacggc catccgcgcg ctgatggcgg aaggcgataa
    37081 agccattgaa ggcaccgacc gttcttcact acgcattctg ggttccgtcg gcgagccgat
    37141 caatcccgaa gcgtgggaat ggtactggaa gaagatcggc aaggaaaaat gtccggtcgt
    37201 cgacacctgg tggcagactg aaacaggcgg ttttatgatc acgccgctac caggcgctat
    37261 cgaactgaaa gccggttccg ccacccgtcc tttctttggc gtacagcctg cgctggtgga
    37321 taacgaaggc catccgcaag aaggcgcgac ggaaggcaat ctggtcatca ccgattcctg
    37381 gccgggccag gcgcgcactc tgttcggcga tcatgaacgt tttgagcaga cctatttctc
    37441 tacctttaag aatatgtatt tcagcggcga cggcgcgcgt cgcgatgagg acggctatta
    37501 ctggatcacc ggtcgcgtgg atgacgtgtt aaacgtctcc ggccaccgtc tgggtacggc
    37561 ggaaatcgag tcagcgctgg tggcgcatcc gaagatcgcc gaagcggcgg tggtgggtat
    37621 tccacacgct atcaaaggcc aggcgattta cgcttatgtg acgctcaacc acggcgagga
    37681 gccgtcgcca gaactgtacg cggaggtgcg caactgggta cgtaaagaga ttggcccact
    37741 ggcgacgccg gacgtgctgc actggaccga ctcactgcca aaaacccgtt ccggcaaaat
    37801 tatgcgccgc attttgcgca aaatcgcggc gggcgatacc agcaatctgg gcgatacctc
    37861 gactctcgcc gatcctggcg tggtggagaa actgctcgaa gagaagcagg ccatcgcgat
    37921 gccgtcataa ccataaatgc cggatggcaa cgcgaacgcg ttttatccgg cctacgaccc
    37981 tacccctgcc ctctctcaaa ccgggagagg gaaatataaa aaccctcccc caaaggattt
    38041 cgtgttacag gaaggcggca agcgagcaca ccctcagcag catagttcac tatgtggctg
    38101 gggcgcgcga gtgcggccag cgcgcctgta gcgcgaaaga cgcaggggga cctctggaga
    38161 gctctgtgat gaatgaccaa atttatcagc ggatagaaga cagtgcgcgt ttcagggaat
    38221 tagttgaaaa acggcaacgg tttgccacga ttctgtcggt tatcatgctg gcggtttata
    38281 tcagctttat tttactgatc gccttcgcgc ctggctggct gggcacgcct ctacatgcgg
    38341 gaaccagcgt cacccgagga attcccattg gcgtcggggt gattgtgatt tcttttgtgt
    38401 tgaccggaat ttatatctgg cgggcgaatg gcgaattcga tcgtcttaat aacgccgtac
    38461 tgcatgaggt gaaagcatta tgaagagagt tctgacggcg ctcgccgccg cactcccctt
    38521 cgccgctcat gcggcggatg ccattagcgg cgcggttgaa cgccagccca ccaactggca
    38581 ggcgattatc atgtttttga ttttcgtcgt gtttacgctc ggtattacct actgggcctc
    38641 taaacgcgta cgttcccgta gcgactacta cacggctggc ggcaatatca ccgggttcca
    38701 gaacgggctg gcgattgccg gcgactatat gtccgccgcg tcatttctcg gcatttccgc
    38761 gctggtgttt acctccggtt atgacgggct gatctattcg ctgggcttcc ttgtcggctg
    38821 gccaattatc ctgtttttga ttgccgagcg cctgcgtaat ctgggacgtt atacttttgc
    38881 tgacgttgcc tcttatcgcc tgaaacaggg gccaatccgt attctttcgg cctgtggctc
    38941 cctggtagtg gtggcgcttt atctcatcgc ccaaatggtc ggcgccggta aactgattga
    39001 actgctgttc ggcctcaact atcacatcgc cgtagtgctg gtcggcgtgc tgatgatgat
    39061 gtacgtgctg ttcggcggga tgctggcgac aacgtgggtg caaattatca aagccgtcct
    39121 gttgctgttt ggcgccagtt ttatggcctt tatggtgatg aaacacgtcg gctttagctt
    39181 caataatctg tttaccgaag ccatggcggt acacccgaaa ggcacggcga ttatgagccc
    39241 aggaggattg gtgcaagatc cgatttcggc attgtcgttg ggtctgggac tgatattcgg
    39301 caccgccggt ttgccgcata ttctgatgcg tttctttacg gtcagcgatg cccgcgaagc
    39361 gcgcaagagc gtgttctacg ccaccggttt tatgggctat ttctacattc tgacctttat
    39421 tatcggcttc ggcgctatca tgctggtggg ggcgaatccc gcctataaag atgccgcagg
    39481 cgcgctgatt ggcggcaata acatggcggc ggtgcatctg gccaacgcgg taggcggcaa
    39541 cctgttcctc ggctttattt cggcagtggc gtttgccacc attctggcgg tggtcgcagg
    39601 tctgacgctg gcgggcgcat cggcggtgtc gcatgacttg tacgccaacg tgttccgcaa
    39661 aggcgcaacc gaacgtgaag agctgaaggt gtcgaaaatc accgtcctgg tgctggacgt
    39721 gatcgccatt atcctcggcg tcctgtttga aaatcagaac atcgccttta tggtgggcct
    39781 ggcatttgct atcgccgcga gctgcaactt ccccatcatt ctgctttcca tgtactggtc
    39841 aaaactgacc acgcgcggcg ctatgctggg cggctggtta ggtttactga cagcggtggt
    39901 gctgatgatt cttggcccta ccatttgggt gcagatcctc ggccacgaaa aagcgatctt
    39961 cccgtatgag tatccggcgc tgttctctat cagcgtggcg ttcctgggga tctggttctt
    40021 ctcggccacc gataactcgg cagaaggcaa ccgtgaacgt gagcagttcc gcgctcagtt
    40081 tatccgctcc caaacgggat tcggcgtaca acaagggcgt gcgcattaat cttaccgttt
    40141 cctccggccc tgtgggtcgg aggaaaatca gaacatcacc ctcgccacca gcggggctgc
    40201 cagcaccatc accacgccgg acagcatcat taccagactg gcgacgacgc cctcctgctg
    40261 accaagttca taggaacgcg ccgtgcctgc cccatgtgac gccgcgccga atcctgcccc
    40321 ttttgccatg ccttcccgga tagagagacg caaaaatagc gcgtcgccga ccgccatgcc
    40381 aaacacgcca gtgacgacca cgaacagcgc caccagatcc ggctgcccgc ccaggggttc
    40441 tgccgccgcc agcgcaaacg gcgtagtaac ggaacgtacc gccagactac gctgaatctc
    40501 atccgataac gtgaacagac gcgccagcca aacggaactg gtgaccgcca ccaccgtcgc
    40561 cgtcactaca cccgcggtga gcgacatcca gtgacgtttg ataatcgcga ggttatcgta
    40621 caccggcacc gcaaaggcaa tggtcgccgg gccgagcagc cacaatagcc agtgcgattc
    40681 gctaatatag ttttgccagg agatatgacc gaacaccagc attaacacca gcagtgccgg
    40741 cgtcaacact aatggcatca acggcaattt gcgaaaacgg cgatacagac gcttattggc
    40801 gaagtaaatt cccagcgtaa tcaccaggca cagtacgctt aactgaacgt tattcacggt
    40861 ttagcctgct catctcatag cgatacactt tatccaccac ccacgccgtc gcgccgagta
    40921 ccattaaggt actgatcgct atcaccgaga aaatgcgcca gccgtccacc agtaacagat
    40981 gggcatagtt cactaccgcc acgacggcgg gaacaaagaa taacagcatc tccgccagca
    41041 gccagcgtgc gcctgcgcgt acccagctaa gcggaataat ccggcaaacg atcagcgcca
    41101 acataagtac catgccgacc agattcgcgg gcaacggcag gtgcagccag gagacaagat
    41161 attgggaaaa aatgaataaa cctgcataga gcagtacctg aaccggtacc tggagtcgtt
    41221 gcacaacggc aggcgtaacg cggcttatcg ccacagccat gagggaatgt cctgaaaaat
    41281 aatacggagc gccagtatag agaacctccg tcacgggcag aaatgaatta aaatcattgc
    41341 aggcatagtc ggaaggaata atcatggata tcagaacgct gcgttatttt gtcgaggtgg
    41401 tgcgccagca aagtttcacc cgcgcagcgg agaagttatt tgtcacccag cccaccatta
    41461 gcaagatgct gaaaaatctt gaagatgagc ttaactgtac gctactgatc cgcgacggac
    41521 gtaagttatt gctgaccgat accggacgcg tggtgtttga acgcggtctg gcgatcctcg
    41581 ctgagtttcg ccagttagag gccgagttga gcgatattaa ccatctcaat aagggcgtgc
    41641 tgcggctggg tattcccccg atggtcggca tgttgatggc tgggccaatc agtttgtttc
    41701 gacaacgcta ccctggcgtt gaactcaaaa tttcggagtt tggcggcctg acggtacagc
    41761 aggcggtaat gaatggcgag ctggatgttg cgatgaccgc gctcccggtg gaagaagcga
    41821 gcgggctgac gacattatcg ctgttcagcc atccgctgtg cgtgctggtt ccccgttccg
    41881 gtcagtggac aacctgcgac tccatcgcgc ctgaagctct ggcggagcat cctcttctta
    41941 tctataacga agactttgcc ctgagccgcc agttgatgac cttatttagc cagcatgacg
    42001 taaaaccacg gattgccgtg cgcagcgggc aatgggattt tctcgccgcc atggtgcaag
    42061 cgggcgtcgg catcgccatt ttgccggagc cgatttgtca gcgtctggat aaggccacgc
    42121 tgcgctggct accgctggaa agtgatctcc gctggcagtt gggcatgatt tggcgcgagg
    42181 gcgtgtatct gtcgcacagc gcccgggcat ggttaacctg ttgcgaaggg ttttggctga
    42241 aacaaccgta agccatgggt taaaaccctt gccggatggc ggcgcaagca ccttaccggg
    42301 cctacttgta ggcccgataa gcatggcgcc accgggccac aaggactact gattttctat
    42361 cagtagagct tccatcaaat ccaggtcgtg cagcagcttt tgcaatgttt cattgctgat
    42421 ttctcgcgtg gcgcgcagat gatacaactc ggcgcgttcg gaacgcagcg ccgccagacg
    42481 gaaacgtcgc tccaggtttt cttcctgtat ggagctttcg acatcgtttc gcccatcggc
    42541 acggcgacgc aagttaccaa tgacacgcga gcttacttca gtaagcaact gattatcgat
    42601 gttttcttcg gtatccgccg ccagacgctc ttccattttc tgaatggcaa caatcgccac
    42661 ttccgccgtc gccgcgcggg cgatacgctc ctctttcaac tgttgcgcat gatcggcgac
    42721 ttccagatgt tgcaacagca gcggcagcat gatcacgccg acaaacaacg agaacagaat
    42781 gacgccagcc gccaggaata ccagttcata acgcgccgga aatccgctgc catccggcaa
    42841 aagtaacggt atagagagca caccagccag ggtgatcgcc ccacgaacgc cagcgaagga
    42901 agcaatcaga atttcacgcg acgtccagct ggcgaactcc atcggtttct tcttcaaaaa
    42961 gcgcaggctg aactttttca tggtccacag ccagccgaag cgaaccagca tcaatgccgc
    43021 ataaatcagc acgatatcgg taaagagcat ccaggtttcg acattcgggt cagcttccgc
    43081 cgccgccagc gaagattcca gaatccctgg caattgcagt cccaacagca gaaagaccat
    43141 accgttaaag acaaattcca gcatcgccca ggtactgttc gcgcgcaaac gcattgccag
    43201 cggcgcgcgg cgcattacgc cagaacgggt gatggtcatc ccggcggcaa ccgcggccag
    43261 gatgcctgag acgccaatat gttcggcaat caggtaagac gcgaagggca gcagaaacag
    43321 caggacgatt tgcgtcgcgg gctcatcgcc gccccagcgg ctcaaaaaac gcagcgagcg
    43381 gccatacagc caactgacta caaaacccgc cagaataccg ccgatagcga ccttaaaaaa
    43441 ttccagcgtc gcgccgccga cggtaaagac catcgtcccc atcgccaccg cgacggcgaa
    43501 tttcagcgat accagaccgg aggcgtcgtt cattaacgcc tctccctgca gaatgcccat
    43561 gatttttttc gggatacgcc cctcgcccac aattccggag agcgctaccg catcggtcgg
    43621 cgacagcacg gcggccagcg caaatgcggg gatcagcgga atgccgggca ccagccaata
    43681 aatcaggaag ccgattccca caaccgttac caggaccagc gccagcgcca gcccgaaaat
    43741 ctctcgtcca tgctcaagaa attcacgggt cggcgttttc cagccatccg caaacagcag
    43801 cggcggaata aacagcacca ggaagagttc cgggtcgaat tccacatgca aaccaaacgt
    43861 cggccacgcc aacagcgcgc caatggcgat ctgcataagg ggtaaaggaa gctggaaggg
    43921 taatacacgc gtaaataccc ccgacagcga gaccacaagg gtcatgatga gtattgtgaa
    43981 gaaaatttcc atgcgttccc tgtttgcgat gttttttatg atggagaaag gcatcatgcc
    44041 tcggtttcac cttcttcaga ttaacgcaaa aggtaacgtg atgtgtcctg aaaatgaaaa
    44101 cgggcgacca acgccgccca tttttcagaa tgaaggcaga actagatagc ccagccgccg
    44161 gcataaaaag cgaccagcgc gaccgcaatg acgacagttc cgatattcag cttacgccat
    44221 tcaccagaaa ccagacgccc gacgaccagc gtggcaaagc cgatcataat cccggtgacg
    44281 atgttacagg tcagtacaat aaatacagcc gttaccagcc ccgccatcgc atcgacgaaa
    44341 tcagcaaaat cgattttcgc cacgttactc agcatcagca gaccgacata catgagcgcc
    44401 ggggcggttg cgtagacggg aacgagataa gagagcggcg aaagaaacaa gatcagcaaa
    44461 aacagcacgc ccacggtaat cgccgtcagg cccgttttac cacccgccgc cgtaccggcc
    44521 gcagactcga tatacaccgc ggctggcgcc gccccgacca ggccggagaa aacgctactc
    44581 agtgagtcgg tggttagcgc tttgccgcca tcgataattt gtccgtctct gtccagcaga
    44641 ttagcctgcc ctgcgaccgc acgaatcgtg ccggtcgcat caaacaccgc cgtcatcacc
    44701 agcgccagca cgcttggcag aacgacaggg tttaacgcgc ccataatatc caggctgccg
    44761 atcagcgagt tgccgttttc atcgctcaac gaaggcatgg cgaaaatgcc ggaaaaatgg
    44821 acgttaggat cgaagagcaa acccacaata gaaatgccaa taatggtcaa cagaatgccg
    44881 ccggggactt tcagcttttc cagaccgaga ataacagcca gacccacaag cgacataatc
    44941 accgggaagg tatcgaaatc gcccagcgcg accggcaggc catccagcgg gtttttaatg
    45001 accaggccga cgccgttggc ggcaatcagc aacaaaaaca ggccaatacc gataccggtt
    45061 ccgtgggcca cgccctgcgg caagttacgc aaaatccagc tacgaatgcc ggtagcggag
    45121 ataatggtaa acagtacgcc catcaggaat acggcgccaa gcgcgaccgg gacgctaata
    45181 tgctgcccca ggaccaggct aaacgcggta aacgccgtca acgagatagc gcaaccgata
    45241 gccagcggca gattcgccca tagccccata acaatagagc cgacgcctgc gaccaggcag
    45301 gtcgctacaa agacggcggc aggcgggaac ccggctttac ccagcatccc tggcaccacg
    45361 atgacggagt aaaccatcgc gagaaacgtg gttaagccag caacgacttc ctggcgaacg
    45421 gtgctcccgc gttgtgaaat tttaaaccag gcgtcgagtg aaccgccggt acgcgctgaa
    45481 ggcgtagaca tagaaaacat cccctgagaa tttattattc gtcggtatac gtgggaggta
    45541 atccactaac agcgcaacgt tatctccttg tgctacattt acgacagccg gggcgccgca
    45601 aaaaagcaaa cgtttagctc cacgtataca aaacgggtgg caaaaaaaag caaacgatta
    45661 tccagcgatc atcaacgctt tttcaactga actttgccgc tttttatgct tttctgctta
    45721 gtatgctcaa taaatagcca gacgatgcgc aaacgttatc gtccctgcgc aatccagcaa
    45781 caatttttcg catcgctgtt agcaaatacg ttgcgcaatc tgctcacaaa aacgccatta
    45841 tccgccggga atggtaaacg gaccgccctg ctgaatcgct cgctgccagg ctggacgcat
    45901 ttctacccgc gctttccatg cgttgatatg gtcgagatga gcgattccgc ctcgggcaag
    45961 cagcgcaaat agcgggaagc tcatctggat atccgccata cttaactgct ctccggcaaa
    46021 ccaggggtga tttgccagat gcccgtcaat aaagcgcgca tgggtttcca gttgcggatt
    46081 gaggtacgct ttttgcgcgc ccttaccgat cacgccgccc aacgttcgca ggcccaatgg
    46141 taccggcggt ttacccagag aggtaaagag cagtctcatc aatagcaagg gcatgagcga
    46201 accttcagcg taatgtagcc agaatcgata gtgttgtttt ctctgcgcat ccgcaggctt
    46261 aaagcgtccg atattgtcgt aagtgtcctg caaatattcc aggatggcgc ccgattccgc
    46321 aataaccata ccgtgatctt cgataaccgg agacttgccc agcggatgca cttttttcaa
    46381 tgccggcggc gccagcatgg tcttttcacg ctggtaacgc acaatctggt aaggcaacgc
    46441 cagctcttcc agcgcccaga ggatgcgctg cgaacgagac tgatttaaat ggtgcaccgt
    46501 cagcatggct gtctcctgta aggtatgcca actaactata gaaaattatg gcagttgccg
    46561 taaaaatttc ggctaaaaaa tcagcatttc gctggcgaac agggcgtcgt cgcttacact
    46621 tacagtatca acacaaaccg gaacctccac cacgtgctca atatgagagg tgttgacgtc
    46681 gggggaaacc ctcctgtaat cagcgggata gagcgaaaga caaagaccgg aaacaaacta
    46741 aagcgccctt agcggcgctt tagttttagg tgagctcagc ccgatggccg agtgcatgtt
    46801 aatcatcttc aagcagccgg gcgcccgtcc cgtgttcgcc aagcctgtcg cctggattcc
    46861 gcagcggaca gtcgctacgc gataaacagc cgcagccgat acaaccgtcc agctcatcgc
    46921 gcaacgccac cagcgtatga atacgtcggt ctaactcttc gcgccactgc gaggagagct
    46981 gcttccactc tttcgcgctt aacgtatgcc cttccggcaa gataccaaac gcgtcgccga
    47041 tagttgccag cgggatgccg atacgctggg caatcttgat aatcgcgaca taacgcaaca
    47101 cgtcacgctt gtatcgccgt tggttaccgc tattacggat actggtaatt agccctttgc
    47161 tttcatagaa gtgcagggcg gacacagcaa caccgctacg tttcgcaact tcccccggcg
    47221 tcagtaaggc ttttaaacgg ggagattttt tttccataaa tcgctttacc tcaagttaac
    47281 ttgaggaatt atactcgccc gcagacaaaa cgacgaatcg aatactgttt aagaggcaac
    47341 aatatgtcgc atcagcagat aattcagacc cttatcgaat ggattgatga acatatcaac
    47401 caaccgctaa acattgatgt ggtggcaaaa aaatcgggtt actccaagtg gtatttgcag
    47461 cggatgtttc gtacggtaac gcatcaaaca ttaggcgagt atattcgcca gcgccgtctc
    47521 ctgttagcgg ccgttgagct acgaacgacc gagcgcccga tttttgatat cgcgatggac
    47581 ctgggctatg tatcgcagca aaccttctcg cgtgtattcc gccgcgagtt cgatcgcact
    47641 cccagcgatt accgtcaccg cctgtagggc gtctgcccgc gtatcgtcag aggcgcgggc
    47701 gtttgttgta gccagacgat gaattcctgc ggcggtaacg ccttcgcaaa gtgccatccc
    47761 tgacaatact gcacgccgcg ttttagcaac cagctaacct gttcagccgt ttcaaccccc
    47821 tcagcaatga tttttagccg caaactttgc gccatttcaa taatatgttc cacaatcaaa
    47881 tggctggcgc tattagtggt tagcgtatcg acaaaagatt tatcaatttt taaaaggtcg
    47941 acatttaatg agtacaggtt atgcaagttc gaatagccgg taccaaagtc atcaattgct
    48001 acctcgtatc ccgcctggcg aaacgcctga ataatcggcg tcattttcgg cacatcaata
    48061 aatccgcgct cggtcacttc aacctttatc tgttgcgcaa gcactgaatg ctgacgcgtt
    48121 ttttcatgaa tcatcacaat tagtcgggaa gagagaaaat cggcggcaga gagattgata
    48181 gagacataaa gatgcgggtg cgcggccaga aaaccaccta aatcattaaa tacctcttcg
    48241 acgacataat cggtgatctg ctcaatcatc ccctcttttt ccgccagagg aataaattcg
    48301 cacgggctca tcaccggacc gtgataaccc ggccaacgca atagcgcttc ggcacctaca
    48361 catgtcccgt ttcggatatc aatgatcggc tgataatgaa ggcaaagctg gtgcctggta
    48421 atggcccgtt gcagcaatcg acgcggtgag taatatgcct gccgggatcg tgaccacata
    48481 aataagacga taatgctaca gatgatccct aacggtagcg ttaacgtaag ctgatgaaag
    48541 aggttctggt aaaagcgttg ctttgaggtt gaaacaatcg cggcaaccgg tcgttttgct
    48601 gatttaacca gagcatagaa acgctcaccc tgttggaaca caggttcact ccgttgtacc
    48661 aaaggtaata gctgatcagc ctgcgcctgt tcactcaggg agaaaaaggt gttggtcacc
    48721 gtatcataca ttccccaggc caacgccgga tcgtctgaca tcacctcgct ataagataag
    48781 ggattgataa ccgcgacata gtttccccgc tgcatatatg tcattttata accgttgaaa
    48841 aaaggcgtat cacgatagta ataaatagcg atgtcaggct ttcgtttata gtcagcgcgg
    48901 ggaataaaat aaggacttgt tggcgtcata accgtagagc atagaaaacg ctggccctta
    48961 gcataaatca actcattaat gtacaaacga ccgcggataa tattcagcat tcgctgttga
    49021 tgggctggcg tacaggcttg cccctgatat tgttcagcgg catcgcgggc taaatctgct
    49081 tgcaggataa cccgctccgt tttatctaat accaactgcg caaatgaatg taactgattt
    49141 ctggtttcag agactgcccg gatatgagca aaccagatcg ccagcaatac aggaagtaat
    49201 accacaatga tcgttccgag aaatctcaac accttgcgtc gtgtgctttg actcattttc
    49261 agcctatttc cctgcattat ttgtgactat tattggcaaa ataagacgtg aaccaaacgg
    49321 aggtttacgg tgcatgaatt tatcaatatt agcaacagac ttttaccgat caacatttac
    49381 cattaataac tacgcgcaat ctctttcgca taccaggcag gacactaaat atttttgata
    49441 atatcagatt tatactcaag taaacgatgg ggtatacatc tttactcctt tcttttgata
    49501 aataacttga tatttttatc aggtctgaat ttcacgaaaa aaaataaaag agtagtaata
    49561 atacatcttt gctttccggc agtttctcta cggacgcgca gaagtcacac aaaaaataag
    49621 gttataaaac gcacaaaaaa tacattgccg atctggcgaa taagcctgtt tttgtgatat
    49681 agttcacaaa aacaatgaaa cagaaacaat gtttcattcg atgttgatgt gacgtccgtt
    49741 gatagccaga atgtcccacg tttcccggga acaacgccgt gctgtcctgg acaaaggtct
    49801 attcagagga aatgtttcat ggctgccata accactggtg tcgttcttct ccgctggcaa
    49861 ctgttgagcg ccgtgctcat gtttttagcc agcacgctca atatccgttt ccgtaaatca
    49921 gattatattg gtctggcggt gatcagtagc ggtctgggcg tggtatccgc ctgctggttt
    49981 gccaccggtt tactcggtat taccatgatg gatctcgctg cgatctggca taacattgaa
    50041 gccgtgatgg tcgaaacgat gagccagacc ccgccagaat ggccgatggt gctgacctga
    50101 tacgctatcg ctgccgctga agtcgcccac cggttatctc aaggcggaat cgcgcgccag
    50161 gggtagcctt gcgaaccatc acgtccctcg cattgccgtt gatgagggcc gccaggtgtg
    50221 gttatccaaa aatggcaagt ggaatagccc taacagaatc gagctaaact tattgaagac
    50281 gttgccgact cgttaaatga caaaaaaaga cccgtttgtg caacgggtct tttttattaa
    50341 gcagtaccac ctgataacag cgacaagcgc ggcttatttt acattaataa tttatccgga
    50401 gaacaatcac ggattatttt tccacctttc attaccagga cccggtcaaa atactttatc
    50461 aggtatcgac gatgcgtcac catgatcaac gttttcccat gaataaactc atctaagtta
    50521 tcaaaaattt gcttctcggt attctcatcc agatttgatg ttggttcatc ccataaaaag
    50581 acgctggcgt tactgctcag actacgtgct aataataact gctgctgctg tccggatgac
    50641 aggtttttag ccataaaatt caccggaaac ttcagcccca taggatgttg caagataaaa
    50701 ccacagttcg ccagatgaag cgccttgagt actcgtcccc tgtcgttttg cggttttaac
    50761 gcgaaattac tttcaatggt tccggtgaat aaaacatcat gtgtcgtcac cacacttaaa
    50821 tgctgagaaa aaaagttctg cgataaatgt cctaagttat atccatcata taaaatggca
    50881 ccgtctgttg gcgaaaggta gccagatagc attcccagta atgagctttt tcctgcaccg
    50941 cattcgccta tcactgcgac acgctgcccc gcaggtatgt ctatagacag tcgattaata
    51001 atcatcggag attgagcatc atactgataa ctcacgcccc gaatagagat atcgccattg
    51061 cactttgata ttgactgtaa tgccggtgtt ttttctgcct gatcttcatc aaaaaaagaa
    51121 agcagatcct taccggtttt ttctgctgat aaaatagaga ttaatgtaga agaaaaattc
    51181 gaaatgatcc cggaaatacg accagagaca atgacagatg aaacaattgc gccagtagta
    51241 acatcaccct tgattaccat aaaaaaggct attaccataa tagtta
//
LOCUS       DAJVKX010000019        49425 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000019 DAJVKX010000000
VERSION     DAJVKX010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 49425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49425
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.019"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..528
                     /gene="ssaU"
                     /locus_tag="OPY25_001046"
     CDS             <1..528
                     /gene="ssaU"
                     /locus_tag="OPY25_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaU"
                     /protein_id="HCS0926713.1"
                     /translation="VVSSLIKWLWVGVMAFYIVVGILDYSFQYYKIRKDLKMSKDDVK
                     QEHKDLEGDPQMKTRRREMQSEIQSGSLAQSVKQSVAVVRNPTHIAVCLGYHPTDMPI
                     PRVLEKGSDAQANYIVNIAERNCIPVVENVELARSLFFEVERGDKIPETLFEPVAALL
                     RMVMKIDYAHSTETP"
     gene            complement(686..762)
                     /locus_tag="OPY25_001047"
     tRNA            complement(686..762)
                     /locus_tag="OPY25_001047"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(726..728),aa:Val,seq:gac)
     gene            complement(773..849)
                     /locus_tag="OPY25_001048"
     tRNA            complement(773..849)
                     /locus_tag="OPY25_001048"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(813..815),aa:Val,seq:gac)
     gene            complement(1001..2374)
                     /gene="mdtK"
                     /locus_tag="OPY25_001049"
     CDS             complement(1001..2374)
                     /gene="mdtK"
                     /locus_tag="OPY25_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460388.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HCS0926714.1"
                     /translation="MQKYTSEARQLLALAIPVILAQVAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLV
                     MIVLWNAGYIIRSMHNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFLGLLVNIPVNYIFIYGHFGMPELGGIGCGVATAAVYWVMFIAMLSYIKHARSM
                     RDIRNEKGFGKPDSVVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLGVGICMAVVTAIFTV
                     TLRKHIALLYNDNPEVVALAAQLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFFITF
                     TAYWVLGLPSGYILALTDLVVDRMGPAGFWMGFIIGLTSAAVLMMLRMRYLQRQPSAI
                     ILQRAAR"
     gene            2591..3232
                     /locus_tag="OPY25_001050"
     CDS             2591..3232
                     /locus_tag="OPY25_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HCS0926715.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVTLPDYMLEGLETGASVAH
                     NGCCLTVTEINGNQISFDLMKETLRITNLGALRVGDEVNVERAAKFSDEIGGHLMSGH
                     IITTAEIAKILTSENNHQVWFKVQDASLMKYILYKGFIGVDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGRKKLGERVNIEIDPQTQAVVDTVERVLATRENVVRNQADIG"
     gene            complement(3274..4422)
                     /gene="cfa"
                     /locus_tag="OPY25_001051"
     CDS             complement(3274..4422)
                     /gene="cfa"
                     /locus_tag="OPY25_001051"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HCS0926716.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRADITINGSAPSDIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECERLDIFFSKVLRAGLENQLPHHVKDTLRILGAR
                     LINLQSKKRAWIVGKEHYDLGNDLFSRMLDPYMQYSCAYWKDADTLEAAQQAKLKLIC
                     EKLQLQPGMRVLDIGCGWGGLSQYMATHYGVSVVGVTISAEQQKMAQTRCEGLDVSIL
                     LEDYRDLNDQFDRIVSVGMFEHVGPKNYNTYFEVVDRNLKPDGLFLLHTIGSKKTDHN
                     VDPWINKYIFPNGCLPSVRQIAEASESHFVMEDWHNFGADYDTTLMAWHERFINAWPE
                     IAGNYNERFKRMFSYYLNACAGAFRARDIQLWQVVFTRGVENGLRVPR"
     gene            complement(4711..5916)
                     /locus_tag="OPY25_001052"
     CDS             complement(4711..5916)
                     /locus_tag="OPY25_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HCS0926717.1"
                     /translation="MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVS
                     ASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSIFALGSLGMLWVESAAALLTLRF
                     VQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
                     VIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSAMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLG
                     LYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQALRPFPQATGRAAA
                     LQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHADCAETGFPH
                     ANVAHDKSH"
     gene            6029..6961
                     /locus_tag="OPY25_001053"
     CDS             6029..6961
                     /locus_tag="OPY25_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0926718.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFVRRHRDVELTPAGVWFLKEGRSVIKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATQAIPVGGRYAF
                     RDMGTLSWSCVVASDHPLASMPGPLSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     VVVPDWESSATCLSAGLCVGMVPTHFARQWIDSGKWVALTLENPFPDAACCVTWQQNE
                     ASPALAWLLDYLGDSETLNREWLREPEEAPDSGD"
     gene            complement(6958..7983)
                     /gene="purR"
                     /locus_tag="OPY25_001054"
     CDS             complement(6958..7983)
                     /gene="purR"
                     /locus_tag="OPY25_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HCS0926719.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVID
                     NAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQ
                     GDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDN
                     VRNARFFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADG
                     PFRDYRR"
     gene            8279..8368
                     /locus_tag="OPY25_001055"
     CDS             8279..8368
                     /locus_tag="OPY25_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnhF family membrane protein"
                     /protein_id="HCS0926720.1"
                     /translation="MSTDLKFSLITTLIVLGVIVAGGLTAALH"
     gene            complement(8451..9032)
                     /gene="sodB"
                     /locus_tag="OPY25_001056"
     CDS             complement(8451..9032)
                     /gene="sodB"
                     /locus_tag="OPY25_001056"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HCS0926721.1"
                     /translation="MSFELPALPYAKDALAPHISAETLEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIVRTSEGGIFNNAAQVWNHTFYWNCLAPNAGGEPTGKLADAIAASFG
                     SFAEFKAQFTDAAIKNFGSGWTWLVKSADGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPNYLEHFWALVNWEFVAKNLAA"
     gene            complement(9159..9980)
                     /locus_tag="OPY25_001057"
     CDS             complement(9159..9980)
                     /locus_tag="OPY25_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCS0926722.1"
                     /translation="MARINKISITLCALLFTTLPFTPMAHASRQAKATPAVSHVTKTA
                     DKKKSTTKKISKTSKKNVKKTSKTSRSSSASTPKRTTAATKSRHTTHRRNRTAPTSIA
                     ALDVTEKCTTRKGRKPHCVKGKGTLPVSIADAHRAKVQKATKTAMSKLMNQIGKPYHW
                     GGASPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRT
                     QGRGTADHVGVYVGNGKFIQSPRSGQEIKITSLNEEYWQRHYVGARRVMTPKTIR"
     gene            10315..10662
                     /gene="grxD"
                     /locus_tag="OPY25_001058"
     CDS             10315..10662
                     /gene="grxD"
                     /locus_tag="OPY25_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HCS0926723.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALSACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKTQEPDAE"
     gene            complement(10740..11387)
                     /gene="rnt"
                     /locus_tag="OPY25_001059"
     CDS             complement(10740..11387)
                     /gene="rnt"
                     /locus_tag="OPY25_001059"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HCS0926724.1"
                     /translation="MSDNAQLSGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDMTLHFHVEPFAGANLQPEALAFNGIDPSNPLRGAVSEYEALHAIFKM
                     VRKGIKDSGCSRAIMVAHNATFDHSFMMAAAERASLKRNPFHPFVTFDTAALSGLALG
                     QTVLSKACLAAGMEFDGEKAHSALYDTERTAVLFCEIVNRWKRLGGWPLPLPTDK"
     gene            complement(11488..11895)
                     /gene="gloA"
                     /locus_tag="OPY25_001060"
     CDS             complement(11488..11895)
                     /gene="gloA"
                     /locus_tag="OPY25_001060"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCS0926725.1"
                     /translation="MRLLHTMLRVGDLQRSIAFYTNVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVESYDMGNAYGHIALSVDNAAEACERIRQNGGNVTREAGP
                     VKGGSTIIAFVEDPDGYKIELIEAKDAGRGLGN"
     gene            complement(11964..13061)
                     /locus_tag="OPY25_001061"
     CDS             complement(11964..13061)
                     /locus_tag="OPY25_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkene reductase"
                     /protein_id="HCS0926726.1"
                     /translation="MSSAKLFTPLKVGAITATNRVFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGLHSDEQIAAWKKITQGVHAQGGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSAINAGTRTSLRDENGQAIRVETSTPRALDTHEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDRYGGSVENRARLVLEV
                     VDAGIKEWGADRIGIRLSPVGTFQNVDNGPNEEADALYLIEALGKRGIAYLHMSEPDW
                     AGGEPYSDAFREKVRARFHGPIIGAGAYTPEKAEDLIEKGLIDAVAFGRDYIANPDLV
                     ARLQRKAELNPQRPESFYGGGAEGYTDYPTL"
     gene            complement(13120..13719)
                     /locus_tag="OPY25_001062"
     CDS             complement(13120..13719)
                     /locus_tag="OPY25_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCS0926727.1"
                     /translation="MNKQTEHDTREHLLATGEQLCMQRGFTGMGLSELLKTAQVPKGS
                     FYHYFRSKEAFGVAMLERHYACYHQRLTAHFTSGPGNHRDRLLAWYQETLKQFCQQGA
                     ISGCLTVKLSAEVCDLSEDMRSTMDKGAQEIMALLARALEDGRNSHCLHFTGQPLPQA
                     QVLYALWLGANLQAKISRSAAPLENALAHVKTIIATPEQ"
     gene            13822..14061
                     /locus_tag="OPY25_001063"
     CDS             13822..14061
                     /locus_tag="OPY25_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HCS0926728.1"
                     /translation="MAEQLEFFPVASPCRGICQSDERGFCRGCMRSRDERFNWQKMSD
                     AEKQNVLRLCRQRFLRKIRANKPLPSEDPQQPSLF"
     gene            14112..15008
                     /locus_tag="OPY25_001064"
     CDS             14112..15008
                     /locus_tag="OPY25_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HCS0926729.1"
                     /translation="MVQRVTIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALTLAPHLREKLQIVTKCGIATTARAENRLGHYITD
                     RRHIILSAEQSLKDLATDYLDMLLIHRPDPLMDADDVAEAFQHLHQSGKVRHFGVSNF
                     TPAQFTLLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRIRPMAWSCLGGGRLF
                     NDEAYQPLRQELSVIAQELNASSIEQVVYAWILRLPSQPLPIIGSGKIERVRAALEAE
                     TLSLSRQQWFRIRKAALGYDVP"
     gene            15088..15609
                     /gene="sodC"
                     /locus_tag="OPY25_001065"
     CDS             15088..15609
                     /gene="sodC"
                     /locus_tag="OPY25_001065"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HCS0926730.1"
                     /translation="MKRLSLAMVTLLACAGAQAASEKVEMNLVTAQGVGQSIGTVVID
                     ETEGGLKFTPHLKALPPGEHGFHIHAKGSCQPAIKDGKAVAAEAAGGHLDPQNTGKHE
                     GPEGQGHLGDLPVLVVNNDGIATEPVTAPRLKSLDEVKDKALMIHVGGDNMSDQPKPL
                     GGGGTRYACGVIK"
     gene            complement(15585..17624)
                     /locus_tag="OPY25_001066"
     CDS             complement(15585..17624)
                     /locus_tag="OPY25_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCS0926731.1"
                     /translation="MKLSLPALRNTPWFKATSGQWRYALRNTIAMCLALTFAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGATAALIIAGHTLNEPWLFLFSMAA
                     WIGFCTWACAHFTNNAAYAFQLSGYTAAIIAFPMVNIVEITQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSTSDGTALLTALKNMHARLLEHASLLWQPETTDAIRSAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRRQNALLNALLHQQLRLTSVISSLRRMLLNWPTPPENSREVI
                     EQLLAELAKPRADSYTVARIIAPLCPQDEQDYRHLAFWQRLRYFCQLYLRSSRQLYLI
                     ESGAPVDQIHIRRTPGLARHTDNAEAIWSGVRTFCTLTVIGAWSIGVQWESGPGALTL
                     AAISCVLYSIVATPFKSLSLLMRTLVLLSLFSFVVKFGLMVQITDLWQFLLFLFPLFV
                     TMQLLKLQMPKLAGLWGQLIVFMGSFIAVTNPPVYDFADFLNDNTAKIVGVAISWLAF
                     AILRPGSDAVKSRRHIRALRRDFVDQLSRHPSHSESEFESLTYHHVSQLSNSQDALAR
                     RWLLRWGVVLLNCSHVVWQLRAWESRSDPLSRVRDICISLLRDVMSERDVQQRPLAVT
                     LQELQRICDTLAHHHQPAAHELAAIIWRLHCSLSQLEQAPAQGTLSPGYLMTPQA"
     gene            complement(17624..18484)
                     /locus_tag="OPY25_001067"
     CDS             complement(17624..18484)
                     /locus_tag="OPY25_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012218841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HCS0926732.1"
                     /translation="MSLKTIKYFSTLIVAVVAVLAAWWLWNYYMQSPWTRDGKIRAEQ
                     VSVTPQVSGSITQLNIKDNQFVNAGDVLFVIDKTPFHIAELNAQAQLAKAQSDLAKAN
                     NEADRRRHLSRNYISAEDLDSANLNVKAMQASVDVALATLKQAQWQLSQTEVKAPVSG
                     WVTNLSTRTGDYASTGKPLFALVDSHSFYVMGYFEETKLRHIREGEPALITLYSGNVK
                     LQGHVGSIGRAIYDQSVESDSGLVPDIKPNVPWVRLAQRVPVRIEFDALPQDITLVSG
                     TTCSVAIGQR"
     gene            complement(18487..18723)
                     /locus_tag="OPY25_001068"
     CDS             complement(18487..18723)
                     /locus_tag="OPY25_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HCS0926733.1"
                     /translation="MKCILNATGLPLQDLMLGASVYFPPFFKAFALGFVIWLFIHRLL
                     RDRIYSDEIWHPLLMDLSLFTLCVCLGLVLLIVW"
     gene            18918..19358
                     /gene="slyA"
                     /locus_tag="OPY25_001069"
     CDS             18918..19358
                     /gene="slyA"
                     /locus_tag="OPY25_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460407.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HCS0926734.1"
                     /translation="MKLESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQ
                     LPPDQSQIQLAKAIGIEQPSLVRTLDQLEDKGLISRQTCASDRRAKRIKLTEKAEPLI
                     AEMEEVIHKTRGEILAGISSEEIELLIKLVAKLEHNIMELHSHD"
     gene            complement(19406..19873)
                     /gene="slyB"
                     /locus_tag="OPY25_001070"
     CDS             complement(19406..19873)
                     /gene="slyB"
                     /locus_tag="OPY25_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HCS0926735.1"
                     /translation="MIKRVLAVSLMGLSLAGCVNNDSLSGDVYTASEAKQVQNVTYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTIGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSAGQRVVLASNGSQVTVSPR"
     gene            20146..21267
                     /gene="anmK"
                     /locus_tag="OPY25_001071"
     CDS             20146..21267
                     /gene="anmK"
                     /locus_tag="OPY25_001071"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HCS0926736.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHL
                     KKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLAQQRLQPRDIVAIGCHGQTVW
                     HEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPT
                     EKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQ
                     VILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLTAFPGADARDVQATLAELTAV
                     SIAQQVLLNGGCERLMVCGGGSRNPLVMARLAALLPGIEVSTTDKAGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS"
     gene            21355..21684
                     /gene="mliC"
                     /locus_tag="OPY25_001072"
                     /pseudo
     CDS             21355..21684
                     /gene="mliC"
                     /locus_tag="OPY25_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460410.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
     gene            21743..22399
                     /gene="pdxH"
                     /locus_tag="OPY25_001073"
     CDS             21743..22399
                     /gene="pdxH"
                     /locus_tag="OPY25_001073"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HCS0926737.1"
                     /translation="MSDNNQLQQIAHLRREYTKGGLRRRDLPAEPLTLFERWLGQACD
                     ARLADPTAMVVATVDDKGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHQIEHNPRISLL
                     FPWHMLERQVMVTGKAERLSTLEVVRYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSIEQMEFWQGGEHRLHDRFLYQRDDGAWKIDRLAP
                     "
     gene            22526..23800
                     /gene="tyrS"
                     /locus_tag="OPY25_001074"
     CDS             22526..23800
                     /gene="tyrS"
                     /locus_tag="OPY25_001074"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCS0926738.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEDALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVA
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNRDDQGISFTEFSYNLLQGYDFACLNKLHGVALQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMDIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLVAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDAELQPSRGQARKTIASNAVTINGEKQS
                     DPEYIFNDEDRLFGRYTLLRRGKKNYCLICWK"
     gene            23860..24519
                     /gene="pdxY"
                     /locus_tag="OPY25_001075"
                     /pseudo
     CDS             23860..24519
                     /gene="pdxY"
                     /locus_tag="OPY25_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460413.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase PdxY"
     gene            complement(24549..25154)
                     /gene="gstA"
                     /locus_tag="OPY25_001076"
     CDS             complement(24549..25154)
                     /gene="gstA"
                     /locus_tag="OPY25_001076"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HCS0926739.1"
                     /translation="MKLFYKPGACSLASHIILREIGKDFTLDGVDLAKKRLENGDDYL
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVSSLARYHTLEWLNYIA
                     TELHKGFTPLFRPDTPETLKPAVRAGLEKKFQYVDESLSDDQWICGQRFTIADAYLFT
                     VLRWAYGVKLNMDGSTHIESYMQRVAKRPTVAAALKAEGLN"
     gene            complement(25259..26764)
                     /gene="dtpA"
                     /locus_tag="OPY25_001077"
     CDS             complement(25259..26764)
                     /gene="dtpA"
                     /locus_tag="OPY25_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HCS0926740.1"
                     /translation="MSTANKKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKILGTKRVIMLGAVVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYAKDDPRLDGAFTMYYMSVN
                     IGSFFSMLATPWLAARYGWSTAFALSVVGMLITVVNFAFCQRWVKSYGSKPDFEPINF
                     RNLLLTIVGIVVLIAVATWLLHNQDIARMVLGVIALGIVIIFGKEAFSMHGAARRKMI
                     VAFILMLQAIIFFVLYSQMPTSLNFFAIRNVEHSILGIAFEPEQYQALNPFWIITGSP
                     ILAAIYNRMGDTLPMPMKFAIGMVLCSGAFLILPLGAKFANDAGIVSVNWLIASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANIIGGYVANLMAVPSDVTDP
                     LMSLEVYGRVFMQIGIATAVIAVLMLLTAPKLNRMTQDDDTAEKGSKAATV"
     gene            complement(27365..28000)
                     /gene="nth"
                     /locus_tag="OPY25_001078"
     CDS             complement(27365..28000)
                     /gene="nth"
                     /locus_tag="OPY25_001078"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCS0926741.1"
                     /translation="MNKAKRLEILTRLRDSNPHPTTELNFTSPFELLIAVLLSAQATD
                     VSVNKATAKLYPAANTPAAMLELGVEGVKSYIKTIGLFNSKAENVIKTCRILMDKHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPNEFKVDCHHWLILHGRYTCIARKPRCGSCLIEDLCEYKEKVDI"
     gene            complement(28000..28692)
                     /locus_tag="OPY25_001079"
     CDS             complement(28000..28692)
                     /locus_tag="OPY25_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HCS0926742.1"
                     /translation="MSEIKDIVVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTVSALRRWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPWLSALDGFSIGMGATGAMFVLGSLREILGNGTLFDG
                     ADSLLGGWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAVKYLIDEKMKKRRAETA
                     PSAVPAGETGKV"
     gene            complement(28695..29315)
                     /gene="rsxG"
                     /locus_tag="OPY25_001080"
     CDS             complement(28695..29315)
                     /gene="rsxG"
                     /locus_tag="OPY25_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HCS0926743.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAVINQMTKSTIHEQALQQQHA
                     LFDQVLPPDRYNNNLQESCYLVDAPALGKGTHRVFIARKDDKPVAAIIEATAPDGYSG
                     AIQLIVGADFNGTILGTRVTEHHETPGLGDKIERRLSDWITHFSGKTISGENDTHWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAESLPAQLPHLTACGE"
     gene            complement(29319..30377)
                     /gene="rsxD"
                     /locus_tag="OPY25_001081"
     CDS             complement(29319..30377)
                     /gene="rsxD"
                     /locus_tag="OPY25_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HCS0926744.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLIAALPGIAAQTWFFGWGTL
                     FQIVLAAITALVAEAIVLRLRKQSVASHLQDYSALLTGLLLAVSIPPLAPWWMVVLGT
                     GFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDILDTLR
                     MIFSGHTASGGDMTLLRIGIDGISQATPLDTFKTSLRAGHSVEQIMQYPIYSGALAGV
                     GWQWVNLAWLVGGVFLLWQKAIRWHIPVSFLLTLALCAALGWLFSPATLASPQLHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(30378..32399)
                     /gene="rsxC"
                     /locus_tag="OPY25_001082"
     CDS             complement(30378..32399)
                     /gene="rsxC"
                     /locus_tag="OPY25_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HCS0926745.1"
                     /translation="MLKLFSAFRKDKIWDFDGGIHPPEMKSQSNGTPLRQVPLAPRFV
                     IPLKQHIGAEGELCVSVGDRVLRGQALTRGRGRMLPVHAPTSGTVIAIAPHSTAHPSA
                     LAELSVIIDADGEDRWIEREGWSDYRAHSREALIERIHQYGVAGLGGAGFPTGVKLQG
                     GDDKITTLIINAAECEPYITADDRLMQDCAAQIVEGIRILAHILQPREVLIGIEDNKP
                     QAISMLRAVLADAHDISLRVIPTKYPSGGAKQLTQILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVVDGEPITERVVTLTGEAISRPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSVTEMGAPQEEKSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATAHHIADCIECGACAWVCPSNIPLVQYFRQEKAEINAIRLEE
                     KRAAEAKARFEARQARLEREKAARLARHKSAAVQPAAKDQDAIAAALARVKEKQAQAT
                     QPVVIQAGSLPDNSAVIAAREARKAQARAKQAAHPMADSAISGDDPRKAAVEAAIARA
                     KARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAA
                     IARAKARKQEQQTVSEPVEPADPRKAAVAAAIARVQAKKAAQQQVVNED"
     gene            complement(32392..32970)
                     /gene="rsxB"
                     /locus_tag="OPY25_001083"
     CDS             complement(32392..32970)
                     /gene="rsxB"
                     /locus_tag="OPY25_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HCS0926746.1"
                     /translation="MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAIL
                     PQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKMAELLNVEPQPCDGEEQQ
                     AAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CIELRPVNETPDSWKWDLNTIPVRIIPVEQHA"
     gene            complement(32970..33551)
                     /gene="rsxA"
                     /locus_tag="OPY25_001084"
     CDS             complement(32970..33551)
                     /gene="rsxA"
                     /locus_tag="OPY25_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HCS0926747.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLDLIYLRTLAFILVIAVVVQFTEMVVRKTSPALYRL
                     LGIFLPLITTNCAVLGVALLNINLGHHFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(33628..34068)
                     /locus_tag="OPY25_001085"
     CDS             complement(33628..34068)
                     /locus_tag="OPY25_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HCS0926748.1"
                     /translation="MTTTPPQRIGGWLLGPLAWLLVALLSASLALLLYVMALATPQTF
                     KTLSGQETGNLLLWGISFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLVSVLLAV
                     KAFAFSPVSDAFAVRQLLFPLLATALIVPYLKRSARVKTTFVNP"
     gene            complement(34157..34372)
                     /gene="ydgT"
                     /locus_tag="OPY25_001086"
     CDS             complement(34157..34372)
                     /gene="ydgT"
                     /locus_tag="OPY25_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460424.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HCS0926749.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLFDHLNYTLTDDMDIVNMYRAAD
                     HRRAELVSGGRLFDVGQVPQSVWRYVQ"
     gene            complement(34671..34796)
                     /gene="blr"
                     /locus_tag="OPY25_001087"
     CDS             complement(34671..34796)
                     /gene="blr"
                     /locus_tag="OPY25_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HCS0926750.1"
                     /translation="MNRLIELTGWIVLIISVILLGIANHIDNYQPPEPTASVQKK"
     gene            35004..36044
                     /locus_tag="OPY25_001088"
     CDS             35004..36044
                     /locus_tag="OPY25_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCS0926751.1"
                     /translation="MNDKIRVGLIGYGYASKTFHAPLIMGTPGLELAAVSSSDETKVK
                     ADWPAVSVVSEPRHLFNDPHIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALARSTGRVLSVFHNRRWDSDFLTLKALLADGVLGEVSLFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAIQLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTLVEGETRKEENWLTLPGNYPAYYAAIRDALNGNGENPVPASQAIQIMELIELGM
                     ESAKHRATLCLA"
     gene            complement(36118..37119)
                     /gene="add"
                     /locus_tag="OPY25_001089"
     CDS             complement(36118..37119)
                     /gene="add"
                     /locus_tag="OPY25_001089"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCS0926752.1"
                     /translation="MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLI
                     PHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPG
                     YMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHR
                     EKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLN
                     TDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDSEKRALREKVAAA"
     gene            complement(37345..37476)
                     /locus_tag="OPY25_001090"
                     /pseudo
     CDS             complement(37345..37476)
                     /locus_tag="OPY25_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000459379.1"
                     /note="catalyzes the formation of homocysteine and
                     pyruvate from cystathionine; also acts a a negative
                     regulator for the mal regulon but interacting with the
                     transcriptional activator MalT; internal stop; incomplete;
                     partial in the middle of a contig; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(37486..37706)
                     /locus_tag="OPY25_001091"
                     /pseudo
     CDS             complement(37486..37706)
                     /locus_tag="OPY25_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310356.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            complement(37825..39333)
                     /locus_tag="OPY25_001092"
     CDS             complement(37825..39333)
                     /locus_tag="OPY25_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HCS0926753.1"
                     /translation="MKKTLVAAGVVIALGIVWTGGAWYTGKKLENHLAEMVTQANEQL
                     KRTAPEAGVELSYQNYQRGVFSSHLQLVVKPVAGADNTWLKPGQSIVLDESVSHGPFP
                     LAQLKTLNLIPSMASVKTTLVNNDAAKPLFDIAKGDAPFVINTRIGYGGDTRSDISLK
                     PLNYENAGEKVAFSGGEFQLNADKDGNVVSLSGEAQSGLVDAVNEYNQKVQLTFNNLK
                     TDGTSKLASFGERVGDQKLTLDKLSIAIEGKEMAVLEGMEIAGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYHAQTQALLNQPDVAQNPELY
                     QQKVTEAFFSALPVLLKGDPVLTLAPLSWKNAKGETTLNLSLFLKDPATTTAQPQTLA
                     QEVDRSVKSLDAKLAIPMDMAVEFMTQIAKLEGYQQDDAEKLAKQQVQGLSAMGQMFR
                     LTTLKDNTIASSLQYANGQITLNGQKMPLEDFVGLFGMPALSVPDVPALPQQ"
     gene            complement(39436..40611)
                     /gene="manA"
                     /locus_tag="OPY25_001093"
     CDS             complement(39436..40611)
                     /gene="manA"
                     /locus_tag="OPY25_001093"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HCS0926754.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGIANPQQQPMAELWMGAHPKS
                     SSRITTANGETVSLRDAIEKNKTAMLGEAVANRFGELPFLFKVLCAAQPLSIQVHPNK
                     RNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALAPFLAMNAFREFSDIVSLLQP
                     VAGAHSAIAHFLQAPNAERLSQLFASLLNMQGEEKSRALAVLKAALNSQQGEPWQTIR
                     VISEYYPDDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEPKPAGELLTAPVKSGAELDFPIPVDDFAFSLHDLALQETS
                     IGQHSAAILFCVEGEAVLRKDEQRLVLKPGESAFIGADESPVNASGTGRLARVYNKL"
     gene            40811..42457
                     /gene="fumB"
                     /locus_tag="OPY25_001094"
     CDS             40811..42457
                     /gene="fumB"
                     /locus_tag="OPY25_001094"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HCS0926755.1"
                     /translation="MSNKPFFYQDPFPLKKDDTEYYLLTSEHVSVAEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPQASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAALDMYKEVNT
                     GTNLPAQIDLYSVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVDKMRT
                     LGTAACPPYHIAFVIGGTSAEANLKTVKLASAKYYDALPTEGNEHGQAFRDIELEKEL
                     LLEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGFW
                     IEKLERNPGKYIPEALRQAGEGEAVRVDLNRPMSEILQQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDRGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQSQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKRLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQSSQCARCVK"
     gene            42625..44028
                     /gene="fumC"
                     /locus_tag="OPY25_001095"
     CDS             42625..44028
                     /gene="fumC"
                     /locus_tag="OPY25_001095"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HCS0926756.1"
                     /translation="MVTVRREKDSMGVIEVPADKLWGAQTQRSLEHFRISTEKMPVSL
                     IHALALTKRAAAKVNQDLGLLAAEKASAIIEAADEVLAGKHADEFPLAIWQTGSGTQS
                     NMNMNEVLANRASEILGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALREHL
                     IPQLSALTDTLRDKSHAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLRHIEHS
                     LPHVAELALGGTAVGTGLNTHPEYARRVAEELATITAAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEIAIPENEPGSSIMPGKVNPTQCEAVT
                     MLCCQVMGNDVAINMGGASGNFELNVYRPMVIHNFLQTVRLLADGMASFNQHCASGIE
                     PNRERITQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKASAVALGYLSDAEF
                     DAWVRPELMVGSMTPGR"
     gene            complement(44025..44954)
                     /locus_tag="OPY25_001096"
     CDS             complement(44025..44954)
                     /locus_tag="OPY25_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HCS0926757.1"
                     /translation="MSRYDLVERLNGTFRQIEQHLAALSDNLQQHSLLIASVFSLPQV
                     TKEAEHAPLDTIEVTQHLGKEAEALALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNATQLDLENQVQRINQLKTTFEQMVTVESGLPSAARFEWVHRHLPGLITLNAYRTLT
                     LINNPATIRFGWANKHIIKNLSRDEVLSQLKKSLASPRSVPPWTREQWQFKLEREYQD
                     IAALPQQAKLKIKRPVKVQPIARIWYKGQQKQVQHACPSPIIALINTDNGAGVPDIGG
                     LENYDADNIQHRFKPQAQPLRLIIPRLHLYVAD"
     gene            complement(45030..46331)
                     /gene="rstB"
                     /locus_tag="OPY25_001097"
     CDS             complement(45030..46331)
                     /gene="rstB"
                     /locus_tag="OPY25_001097"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HCS0926758.1"
                     /translation="MKKLFVQFYLLLFVCFLVMTLLVGLVYKFTAERAGRQSLDDLMK
                     SSLYLMRSELREIPPREWGKTLKEMDLNLSFDLRVEPLNHYKLDAATTQRLREGDIVA
                     LDDQYTFIQRIPRSHYVLAVGPVPYLYFLHQMRLLDIALMALIAFSLAFPVFIWMRPH
                     WQEMLRLESAAQRFGEGHLTERLHFDNGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSENLTPPESQALNRDIGQLEALIEELLTYARLDRPQNELM
                     LTKPDLPAWLFAHLQDVQSVNPERAVNLLTCVIGDYGALDMRLMSRVLDNLLNNALRY
                     SRTTVQVSLLLDGSQATLIVEDDGPGIEADARERVFEPFVRLDPSRDRATGGCGLGLA
                     IVHSIALAMGGSVVCDDSELGGAKFSFRWPVWHAMPDMTAA"
     gene            complement(46442..48148)
                     /locus_tag="OPY25_001098"
     CDS             complement(46442..48148)
                     /locus_tag="OPY25_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCS0926759.1"
                     /translation="MLMISLVPPLLSRTALLFLLTATGAATAARPAADIILHNGNIIT
                     LNDAQPQASALAISGSRIVAIGDDTATNEWRGDHTRTIDLQGKTVIPGLTDTHIHAIR
                     GGQTWTFETYWYDSPSLKDALDKLRADANRRPHDQWVAVVGSWIPAQFAENRASTVAE
                     LSHALPDHPAYIQYLYDYALVNQRGIDVLGLNDTPPPDLAGIRVERDAKGSATGKLFG
                     DIAAFNQLFASISSNADREGGLRQFFADMNARGVTGIIDPSAGPAAAYEPLFAMRNQG
                     DLPLRVGYRIPVQPEAKGHEAQWFSNLMAFRPARADDGQLAFLGLGESLVAGMNDGVR
                     MAPGFSSSEQDKTALRQVATFAAKRGIPLEIHAYTDDSADAILTIFEQVAQQYDLRPL
                     RWSIAHLNTGSPQTLERMRKLGLAYTVQMGPYFEGLAIRDANPPGATDNSPPVRLALD
                     KGLVVAGGTDSTRIGIAGVWHAIEYHITGIASGGSVRKPASERLTRLEALALYTRHAA
                     WLAFAEQHRGQLSVGKQADLAVLNQPFMTMPEDRIDTIRAVLTLVDGRIVHESPDLNA
                     GQ"
     gene            complement(48307..>49425)
                     /gene="ompS2"
                     /locus_tag="OPY25_001099"
     CDS             complement(48307..>49425)
                     /gene="ompS2"
                     /locus_tag="OPY25_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpS2"
                     /protein_id="HCS0926760.1"
                     /translation="ALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQT
                     YMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYG
                     RNYGVLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQ
                     YQGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRT
                     NEQVNAGGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKN
                     FSTYVDYKINLLDDDDPFYKDAGISTDDIVALGMVYQF"
BASE COUNT        12096 a        12720 c        13247 g        11362 t
ORIGIN      
        1 gtggtttctt ctttaataaa atggttatgg gtaggggtga tggcttttta tatcgtcgtt
       61 ggcatactgg actattcttt tcaatattat aagattagaa aagatctaaa aatgagtaaa
      121 gatgacgtaa aacaggagca taaagatctg gagggcgatc ctcaaatgaa gacacggcgt
      181 cgggaaatgc agagtgaaat acaaagtggg agtttagctc aatctgttaa acaatctgtt
      241 gcggtagtgc gtaatccaac gcatattgcg gtttgtcttg gctatcatcc caccgatatg
      301 ccaataccac gcgtcctgga aaaaggcagt gatgctcaag ctaactatat tgttaacatc
      361 gctgaacgca actgcatccc cgttgttgaa aatgttgagc tggcccgctc attatttttt
      421 gaagtggaac gcggagataa aattcctgaa acgttatttg aacccgttgc agccttgtta
      481 cgtatggtga tgaagataga ttatgcgcat tctaccgaaa caccataaat gcttttggta
      541 tgcttcttca ggccactgcg aaggttaaga gggtaatagc gtatagagca gtgcttgacg
      601 ataaaggtga gagactgaaa ataatcgctt ttagcctggc acaagcacca gatagcgtat
      661 tataaaatta aacaagataa tggattggtg cgtctgaatg gactcgaacc atcgaccccc
      721 accatgtcaa ggtggtgctc taaccaactg agctacagac gcattaaaat gatggtgcgt
      781 tcaattggac tcgaaccaac gacccccacc atgtcaaggt ggtgctctaa ccaactgagc
      841 tatgaacgca acgttgtagg tgacaacggg gacgaatatt agcgtcacaa ccgcaatgag
      901 gcaagaggga aatcgcaatt ttcttcctga aatcacctga ttgcggtgga aatatgcaac
      961 atgtcgaaaa aatagccgcc atgcgacggc tatcgtcgta ttatcgcgca gcgcgctgca
     1021 aaatgatggc ggacggctga cgttgtagat agcgcatccg tagcatcatt aacaccgccg
     1081 ccgaggtcag gccgatgatg aaccccatcc agaagcctgc cggtcccata cgatccacca
     1141 ccaaatccgt taacgccagg atataaccgc tgggtaaacc taacacccag taggcggtaa
     1201 aggtgataaa aaagatggaa cgcgtatctt tataaccgcg cagaataccg ctgccgataa
     1261 cctgtataga gtcggaaatc tggtaaaccg cagcgagcag cattaattgc gcggcaagcg
     1321 ccacgacctc agggttgtca ttgtagagca aagcaatatg cttacgcaga gtaacggtaa
     1381 aaatagcggt aaccacagcc atacaaatgc cgacgcctaa accggtacgc gctgcggttt
     1441 gcgcatccag cgttgagccc tggcccagac gataacccac tcgaatcgtt accgccgcag
     1501 ccagcgacat cggcagtacg aacatcagcg agctaaagtt aagcgcaatc tgatgaccgg
     1561 cgacatccac aatacctaat ggcgaaacca gcagcgcaac gaccgcaaac aacgtcactt
     1621 caaagaacag cgccagcgca atcggcaacc ccagttgaat caggcgcttc atgacgacgc
     1681 tatcaggttt gccaaagcct ttttcattac gaatatcacg cattgaacgc gcgtgtttaa
     1741 tgtaagaaag catggcgata aacatcaccc aatagaccgc cgcagtcgca acgccgcagc
     1801 cgataccgcc gagttccggc ataccaaaat ggccatagat aaaaatatag ttcaccggaa
     1861 tattcaccag caggcccaaa aatcccatca ccatacccgg tttggttttg gccagacctt
     1921 cgcactggtt tcgcgctacc tgaaagaaaa ggtatcctgg cgcgccccac agcagcgcgc
     1981 gaagataacc cacggcttta tcggccagcg ccggatcaat attatgcata gagcggataa
     2041 tgtatccggc attccacagg acgatcatca ccagcacgga gacaaagccc gccagccaga
     2101 acccttgtcg aacctgatgc gcgatacgct cacgacggcc ggagccattg agttgcgcaa
     2161 tcacaggcgt caaggccagc agtaagccgt gaccaaacaa aatggcggga agccagatag
     2221 aggtgccgat agcgacggca gccatgtccg tagcgctata gcctcccgcc atgacggtat
     2281 cgacgaatcc cattgcggtc tgtgccactt gcgcaaggat caccggtatc gctaacgcta
     2341 ataactgacg cgcttcactg gtatacttct gcacgtattc accttttatt ttgttgttat
     2401 atgaaagact aaaaagccgc cgtagtggca gccaaaagaa atagcagggg aaatttcagt
     2461 ctattgtagc ggggtattac tatttctcca gtgaaaaaac agttgttaac ggcgcattgc
     2521 tggcaagctg tttttccacc tgctattgtg ctgaacagtt ctgcgtttat ttatttcagg
     2581 agttgaagat atgtttacgg ggatcgtaca gggtaccgcg aaactggtat cgattgatga
     2641 aaaacccaac tttcgcaccc atgtggtgac gttaccggac tacatgctgg aggggctgga
     2701 gacgggggcg tcggtagcgc ataacggatg ctgtttgacg gtaactgaaa taaacggcaa
     2761 tcagataagc tttgatctga tgaaagaaac gttgcgcatc accaatctgg gcgcgttgag
     2821 ggtaggtgat gaggtcaacg tagagcgcgc cgccaaattc agcgatgaaa tcggtggaca
     2881 tctgatgtcg gggcatatta ttacgacggc ggagatcgcg aaaatcctga cctctgaaaa
     2941 taaccatcag gtgtggttta aagtgcagga tgcgtccctg atgaagtata tcctgtacaa
     3001 gggctttatc ggcgtcgacg gcatcagttt gaccgtcggc gaggtaacgc caacgcgctt
     3061 ctgcgtgcat ctcattccgg aaacgctgga acgtactacg cttggcagaa aaaaactggg
     3121 tgagcgtgtg aatatcgaga tcgatccgca aacgcaggcg gttgtcgata ccgtagaacg
     3181 cgtactggct acacgagaaa atgtggtcag aaatcaggcc gacattggct aacggaaaat
     3241 aagattcccc cgcatgaaat gcgggggaga tgattagcga ggaacgcgca gaccgttttc
     3301 aacgccgcgc gtaaatacca cctgccaaag ctggatatca cgcgcgcgaa acgcacccgc
     3361 gcaggcgttg agataatagc tgaacatacg tttaaagcgc tcgttataat tgcccgcaat
     3421 ctctggccag gcattgataa agcgctcatg ccacgccatc agagtcgtgt catagtcggc
     3481 gccaaagtta tgccagtctt ccattacaaa gtgtgattcg ctggcctcgg cgatttgacg
     3541 aacagacggc aagcaaccgt tggggaaaat atacttattg atccacggat cgacattatg
     3601 atcggttttt ttagaaccaa tagtatggag caggaaaaga ccatccggtt ttaaattcct
     3661 gtcaacaact tcaaaatagg tgttgtagtt ttttggcccg acatgttcga acatgccgac
     3721 ggagacgatt cggtcaaact gatcgttaag gtcgcgataa tcttccagga gaatggagac
     3781 atccagacct tcgcaacgcg tctgcgccat tttttgttgt tcagcggaga tcgttacgcc
     3841 caccacgcta acgccataat gggtcgccat atattgcgac aggccgcccc agccgcagcc
     3901 gatatccagc acacgcatcc ccggttgtag ctgtagcttt tcgcaaatta atttcagctt
     3961 ggcttgctgt gccgcttcca gcgtatcggc atctttccag taggcgcaag aatattgcat
     4021 atagggatcg agcatacggg aaaaaaggtc attaccaaga tcgtaatgtt ccttgccgac
     4081 aatccaggcg cgttttttac tttgtagatt aatcagacgc gcgccgagga tacggagcgt
     4141 atctttgaca tggtggggga gttgattttc aagaccggca cgtaagactt tgctgaagaa
     4201 aatatccaga cgctcgcatt cccaccagcc atccatgtaa ctctcaccta accccaacga
     4261 tccttcctgg aggacgcgtt taaaaaaatc gggattctta acacgaatgt cagacggggc
     4321 ggaaccatta attgtaatat ccgcacgact taacaattcg ttggcgattc ggtaccagtt
     4381 atcatccggt acgctgactt cttctataca cgatgaactc atagtttctc catcactgga
     4441 cggtgatcag aaccttaaaa cagcgtagac gcttttttgg ctttgtgaga aatcccacgg
     4501 acaattccgt gagccagtta tccgacgtag aacagaggaa gggaggagcc cttgccgaaa
     4561 aggccatcca tggtgaatcg ggaacactcc ggttcccgtt aatgcctaat aattatcgta
     4621 atataacaac cgggaatcag tataggccgc aatttttgat gattcaaccg aaaattgtta
     4681 gcgtgctaat taccagcggt taacaagtct ttagtgagac ttgtcgtggg cgacattggc
     4741 atggggaaat ccagtctcag cgcaatctgc atgagactgc attttgtaac ctaacgccgc
     4801 cagaacaacg gtagagagca ttacgctggt ggtggtcagc agcggcgtgc tgatgagcca
     4861 tgaaaccacc aggcttgcca ggaaacataa ccccagttgc agcgtatttt gtagcgccgc
     4921 agcgcgcccc gtggcttgag ggaaagggcg taacgcttgc gcgacgacga tagggtagat
     4981 tgcgccatta gcaatcgcca ttacgcagaa aggaatcagg atctccacca gtgaggcatt
     5041 attcagaagg cccgctcccc aggtggcgat aacgctcagc gcatacagcc ctaacagcca
     5101 cggaagcaat tggtagccct gccatttttg tagcgccgcg cggcaaccat atccgccaat
     5161 cagaaaagcg atggtttgag gaacatagct caggccaatc actgccgggc tgtaacccat
     5221 cgcgctgaga ataaacgggg accctgttag ccacgcaaaa aagctggcgg aacaggcggc
     5281 ataaatcagc acattaccgc gataggtttt agagcgtaac aacgtcgcga aagtgagttt
     5341 atcctgtcct tcggtacgcg cttttaccga tggttttaag cgcagcgccg gcaacatcag
     5401 caacaacgta atcacgaaca gggtggcgaa aatcacctgc catgagaaat gcgtcagtat
     5461 ccagcttccc agtaagggcg caagcgccgg ggataatccc accagtggca tgatcgtggc
     5521 gaagatacgg ttaatttttt gcgaaggata ataatcggtc accagcgctt gccagattac
     5581 cgttgccgca caaacgccga cggcctgcac aaagcgcagc gtcagcagtg ctgccgcgct
     5641 ttctacccac agcatcccca gacttccgag tgcaaagata gataacccca gcagtaaaat
     5701 cggtttacgg ccataacgat ccgatagcgg tccccaaagt agttgcgcga cggcaaagcc
     5761 agctaaaaac aggcttaggc tggcgctgac agcggcggca ggcgtttgta aatccgcctg
     5821 tatggcggca aacgcgggca ggtacatgtc cgtagccaga aatcccagca cgctaaggcc
     5881 ggctaaccag actaaaaaac cttttccagg ttgcatattt gtttctcttt cttatcagac
     5941 agacattgtc gcagagtgta gggagtgaaa ttacggttgt gaaacgttaa tatttgtcca
     6001 gtgaattcaa aatttttgta ggcaaattat gtggtcggaa tactcgcttg aagtggttga
     6061 cgccgtggcg cgcaatggca gttttagcgc ggcggcgcaa gaactgcacc gtgtgccttc
     6121 agcagtcagt tacaccgttc gtcagttaga ggagtggctg gccgtaccgc tttttgtacg
     6181 acgtcaccgt gatgttgaac taacgcctgc tggcgtctgg tttttaaaag aagggcgttc
     6241 tgttatcaaa aaaatgcaga tcactcgcca acagtgtcag caaattgcta atggctggcg
     6301 cgggcagtta gctattgcgg tggacaatat cgtcagacca gaacgtaccc ggcagatgat
     6361 cgtcgatttt tatcgtcatt ttgacgatgt ggaactgctg gtttttcagg aggtgtttaa
     6421 cggcgtctgg gacgcgctct ccgacgggcg tgtcgaactg gcgattgggg cgacgcaggc
     6481 gattccggta ggggggcgtt acgcttttcg ggatatgggg accctgagct ggagctgcgt
     6541 agtggcaagc gatcacccgc tggcgtcgat gcctgggccg ttaagcgatg ataccctgcg
     6601 caactggccg tcgctggtca gggaagacac ttcgcgaacc ttaccgaaac ggattacctg
     6661 gttgctggat aaccaaaaaa gggtcgtcgt accggactgg gagtcatcgg caacctgcct
     6721 gtcggcagga ctatgcgtgg gaatggtgcc gacgcatttt gcccgacagt ggatagacag
     6781 cggaaaatgg gtggcgctga cgttagagaa tccgtttccc gatgcggcct gttgcgtgac
     6841 gtggcagcaa aacgaggcct cgcccgcgct ggcatggctg ctggactatt tgggcgatag
     6901 cgaaacgttg aatcgggagt ggctgcggga gccagaagag gctcccgaca gcggggatta
     6961 acgccgatag tcgcggaacg ggccgtcagc gaccgagcga cgctcaacca ggcgtggatg
     7021 aacttcaata gactgtgact cttcacgctt attgacgatg cgatccaata gcatattaaa
     7081 tgcggtttcg cctaaagagt ctttgggctg gtgaatcgtc gtcagcgccg gggtaaagaa
     7141 acgggcgtta cgcacattgt cataaccgat caccgaaacg tcctgcggta cgcgaagccc
     7201 catttcgtca gctgcgcaaa gcgcgcccat cgccataata tcgccgccgc agaaaacggc
     7261 ggtagggcga tgtgactgcg ataagatttg ctgcatcgcg tggtaaccgg attccggctc
     7321 gaagtcgccc tgaacaatcc agttgtccgg cacgttgatc agcgcctcct ccatggcttt
     7381 cataaagcct gccagccgcc ccgcgcctgt gttgcgctcc agcgggccgg gaataacgcc
     7441 gatatcccgg tggccgcgct caaccagata acgacccgcc atatagccgc ctgcaaaggc
     7501 gttatcaatc accgtgtcgg taaaatcggc cttcgcctca ccccagtcca tcaccaccat
     7561 cggaatatgg cgatactctt ccagcatgga aagcagaggt tctggatact cagaacacat
     7621 caccagcagg ccatccacgc gcttttgcgc catcatggac aggtaggcgc gctgtttttc
     7681 caggttattc caggcgttgc ctaaaatcag cgtatagcct ttctggaaac agtttttttc
     7741 aactgcctcg ataatttcgg caaaataggc cgcttcgctg ctggtcgcca gtaagcctat
     7801 cgacttggta tggttaacct tcaggctacg cgcgacggcg ctgggagagt agtgcagctc
     7861 tttaattgcc gcccagaccg cgttacgcgt ttcttcagcg acaaaacgcg ttttgttgat
     7921 tacgtgtgat acagttgtag tggaaacgtt tgcccgtttc gctacatctt taattgttgc
     7981 cattacattt cactccagac cctcgctaag ctcctgagaa acgccaggta aacgtttacc
     8041 tacacacacc ctaatcgcaa catcagggtt gcggcacgcc ggaaaaacga cacggaacgt
     8101 caggaagggg tcaatggccg ttacgctaat tcagtaagcc tggaattttg tctgatcttg
     8161 aggaaaaggg gaagcgttaa aaacagttat caatataaaa catgagagat ttttgtgcgg
     8221 gaatgtgcaa aaatgcgcta tatcactttt tgtgtgggaa taaaaaggag aaaacttgat
     8281 gagtaccgac ctgaaatttt cgttgattac tacgctgatt gttctgggcg tgattgtcgc
     8341 aggtggatta acggccgctc tgcactgatt tcctctcttc tgagagtggg cgtctcctct
     8401 attctatccc tctctaaaac gcagaaggcg taccttctgc gtactcagac ttatgcggcg
     8461 agatttttcg caacaaattc ccagttaacc agcgcccaga aatgctccag atagtttgga
     8521 cgggcgttgc ggtagtcgat gtaatacgcg tgttcccaca catcaaccgt cagcaacggc
     8581 gttgcatccg tagtcagcgg cgtaccggca tttgaggtag aaacgatagc cagtttgcca
     8641 tcagcgcttt ttaccagcca tgtccatccg gaaccaaagt ttttgatagc ggcatcggtg
     8701 aactgcgctt taaattccgc gaagctgcca aaagatgccg cgatagcatc agccagtttc
     8761 ccggtcggtt cgccgccagc gtttggcgcc aggcagttcc agtagaaggt gtggttccac
     8821 acctgagcgg cgttattaaa gatgccgcct tcggaagtgc gcacgatctc ttccagcgat
     8881 ttgccttcaa acgccgtgcc tttgatcaaa ttgttaagat tggtcacgta agtctgatga
     8941 tgtttgccat agtgatattc cagcgtctca gcagaaatat gcggcgccag agcatctttg
     9001 gcatacggta atgcaggtaa ttcgaacgac attgcttctc tccttattat taatattgcg
     9061 cacgcacaat aaccctggtg cgcgtaagga tagggtagca aattgagagg tggcgcaaaa
     9121 gaagaagtta tcctgtcgtt aaacgacagg ataaaatatt agcgaattgt tttaggcgtc
     9181 atcacccggc gggcgccgac ataatgacgc tgccagtact cttcgttcag tgaggtgatc
     9241 ttaatttcct gaccgctgcg cggagactgg ataaacttac cgttgccgac atagacgcca
     9301 acgtgatcag cggtgccgcg cccctgtgta cggaagaaca ccagatcgcc gtttttcaac
     9361 tcgctacgct caatgggggc cgcgtcacgc aggtgataca tctcattcgc cgttcggggg
     9421 atacggatct tcactaaatc tttataggca taataaacca gaccgctgca atcaaaaccg
     9481 gtgcgcggcg atgcgcctcc ccagtgatac ggtttaccaa tctgattcat gagcttggac
     9541 atcgcggttt tcgtcgcctt ttgtactttt gcacgatgcg catcggcaat agagaccggc
     9601 aatgttcctt tccccttcac gcagtgcggc ttacggcctt tacgcgtcgt gcatttttcc
     9661 gttacgtcga gggcggcgat tgacgtgggc gcggttctgt tacgacgatg cgtcgtatga
     9721 cgagattttg tggcggcggt ggtacgtttt ggcgtagaag cggaagaaga acggctggtt
     9781 tttgaggttt tttttacgtt ttttttgctg gttttactga tctttttagt tgtgcttttc
     9841 tttttatctg ccgttttcgt gacatgagaa acagcaggcg tcgctttggc ttgcctggaa
     9901 gcatgggcca ttggcgtaaa ggggagagta gtaaaaagta aagcacagag cgtgatcgag
     9961 attttgttta tccgcgccac tgagcaatcc tctgttaaag gcaggcgatt catgcctgcg
    10021 tatgatttac aaaacctgat aattctaatc tacaaaagca cagattggta attgcttttg
    10081 gtttctgaag ctatgtttcg ttaacagatg taaaaaaata gcaattaatg ctaaacacga
    10141 acgcgttatc tacaaatcac tgcgcggcaa cccgcttaaa agatattttg tatacaactt
    10201 attcccgcag acggtaaaat aataaggcat gatgaaaatg ttattttccg ttgccagcct
    10261 gacccgttac aatgacaggc ttcggtcgta aaagtagttt aaggaagcga gacaatgagc
    10321 accactatcg aaaaaattca gcgccagatc gctgaaaacc cgattctcct gtatatgaaa
    10381 ggttcaccga aactgccaag ctgtggtttc tctgcgcagg ccgttcaggc gctttcagcc
    10441 tgcggggaac gttttgccta tgttgatatc ctgcaaaacc cggatattcg cgctgaatta
    10501 ccgaaatacg ccaactggcc gacattccca caactgtggg tggacggcga gctggtcggc
    10561 gggtgtgata ttgtgattga aatgtatcag cgtggcgagc tgcagcagct tattaaagaa
    10621 actgcggcaa aatataaaac tcaggagccg gacgcagagt aatctgtgaa aggggaaagc
    10681 gacctgtaaa ggtcgctttt ttaccgccat cgtgagcaag agcggcgttg ttagcctcgt
    10741 tatttgtccg tcggcaaagg taacggccag ccgcccaggc gcttccagcg attgacgatt
    10801 tcacaaaaca gcaccgctgt ccgctcggta tcatacaaag cggaatgggc tttttcaccg
    10861 tcaaactcca tacctgccgc caggcacgct tttgataaca ccgtttgtcc cagcgccagt
    10921 ccgctcaatg ccgcagtatc aaaggtgacg aacggatgaa acgggttacg tttcagcgag
    10981 gcgcgctctg cggcggccat cataaaactg tgatcaaaag tggcgttatg cgcgaccata
    11041 atggcgcggc tacaaccgct gtctttgata cctttacgta ccattttgaa aatagcgtgt
    11101 agcgcctcat attcactcac cgcgccgcgt agcgggttag agggatcgat accgttaaac
    11161 gcaagcgctt ccggctgtaa gttggctcca gcgaacggct ctacatggaa atgcagcgtc
    11221 atgtccggca tcaaccagcc ttgttcatcc attttcagcg tgatggcggc gatttcgagc
    11281 agcgcatcgg ttttagcgtt aaatcctgca gtttcaacgt cgatgacgac aggataaaaa
    11341 ccacgaaaac ggtcgcacag accggaaagt tgagcgttat cggacatctg agtctcttaa
    11401 tacgaaaaaa tgcagcgcgt attatggcaa attttacgcc gggatgcagt aaaacaacgg
    11461 gcgcagtgac ctgcgcccgg cgggggatca gttacccaga ccgcggcctg cgtctttagc
    11521 ttcaatcaat tcgattttat agccatccgg atcttcaacg aaggcgatga tggtcgaacc
    11581 gccttttacc ggccccgctt cacgggtcac gttgccgccg ttctgacgaa tgcgttcaca
    11641 ggcttcagca gcattgtcaa cgctcagcgc gatgtgccca tacgcattgc ccatgtcgta
    11701 gctctcaacg ccccagttat aggttagttc gatgaccgct tcttccgttt ccggaccata
    11761 tcccacaaag gccagcgagt atttgtattc cggattctca ctggtacgca gcaatttcat
    11821 gcccagaacg ttagtgtaaa aagcgatgga acgctgcaaa tcgccgacgc gcagcatagt
    11881 atgcaataaa cgcattttcg ttgtccttaa aatagtcaag atattcaaag tatagcggcg
    11941 atgtgaggcc gctatcaatg aaattacaga gtagggtagt cagtgtagcc ttccgcgccg
    12001 ccgccataaa aactttcggg acgctgtgga ttaagttccg ctttacgttg cagacgcgcc
    12061 accagatccg ggttagcgat gtaatcgcga ccaaacgcca cggcgtcaat cagccctttt
    12121 tcgatcagat cttccgcttt ttctggcgta taggcgccag cgccgatgat gggaccgtgg
    12181 aaacgcgcgc gcactttttc acggaacgcg tcgctgtacg gttcgccgcc cgcccagtct
    12241 ggttcagaca tatgcagata agcgatgccg cgtttgccta acgcttcaat cagataaagg
    12301 gcgtcagctt cttcattcgg gccgttatcg acattctgga aagtgccgac aggagaaagg
    12361 cggatgccga tacggtccgc gccccattcc ttaatgccgg catcaaccac ctccagcacc
    12421 agacgggcgc gattctctac gctgccgccg taccgatcgg tacggtgatt agaagacggt
    12481 gagaggaact ggtgcagcag ataaccgtgc gcggagtgca gctccaccag atcgaagcct
    12541 gcctctcggg cattggcgat agcctggcgg aaatcgttga cgatcccggg gatctcatga
    12601 gtatccagcg cgcgcggcgt ggaagtttct acgcggatgg cctggccgtt ttcgtcacgc
    12661 aaagaggtgc gggttcccgc attgatagcg gatggcgcga cgggcgcttg tccgcctggt
    12721 tgcaggctgg cgtgtgaaat acggcccgta tgccacagtt gcaccgccat atggccgccc
    12781 tgggcatgga ctccctgagt gatttttttc caggcggcga tctgctcatc gctgtgtaat
    12841 cccggtgcgc cggcatagcc tttcgcctgc gcggagattt gtgtggcttc gctgatgatc
    12901 aatccggcgc tggcgcgttg acggtaatat tccgccatta acggcgtagg aatgtcgccc
    12961 ggttcaatac tccgcaaacg cgtcaaaggc gccataaata cgcgatttgt cgccgtgatg
    13021 gcacccacct tgaggggggt aaacagtttt gctgatgaca tagtggctcc tgatataagt
    13081 agaccggtcg tcttgtaata aaggaaataa aaacgcccgt tactgctcag gcgttgcaat
    13141 gatggtctta acatgcgcca acgcattttc cagcggcgcg gcgctacggg atattttggc
    13201 ctgcaaattg gcgcccagcc acagggcata aagtacctgc gcctgtggca acggctggcc
    13261 ggtgaaatgt aaacagtggc tattacggcc atcttccagc gcgcgtgcaa gcagtgccat
    13321 gatctcctgc gcccctttat ccatcgtaga gcgcatatcc tccgacagat cgcagacttc
    13381 cgctgacagt ttcaccgtca ggcaaccgct gatggcgcct tgctggcaaa actgctttaa
    13441 cgtttcctga taccaggcga gaagacgatc gcgatgatta ccgggaccgg aggtgaagtg
    13501 cgccgtaaga cgctgatgat agcaggcgta atgtcgctca agcatggcga cgccgaaggc
    13561 ttctttcgag cgaaagtagt gataaaacga ccctttaggt acctgggcgg ttttgagcaa
    13621 ctcgctaagc cccatgccgg taaaaccccg ttgcatacaa agctgctcgc cggtggccag
    13681 cagatgttcg cgggtatcat gttcggtttg cttattcatg acaggcagta tagtagacca
    13741 gtcggtctac tgcaagcaga gttgccataa tgtcagttag cgtcttcaat agtcataagc
    13801 gccaaacgtt gaggagggga tgtggccgag cagttggagt tttttcctgt agcaagccca
    13861 tgtcgcggta tctgccagtc tgatgagcgt ggcttttgtc ggggatgtat gcgcagccgc
    13921 gacgaacggt ttaactggca aaaaatgagc gatgccgaga aacaaaatgt actgcggctt
    13981 tgtcgccagc gtttcttgcg taaaatacgc gcaaataagc ctctcccatc ggaagatcct
    14041 caacaacctt cactctttta aacgcggaat tgcgtatact caacctcatt attctctatg
    14101 aggaatctgt tatggttcag cgtgtcacca tcgctccaca aggcccggaa ttttcgcgtt
    14161 ttgtcatggg ttactggcgt ttgatggact ggaatatgtc cgcgcgtcag ttagtgagtt
    14221 ttatcgaaga acatctggat ttgggcgtca ctaccgttga ccatgcggac atttatggcg
    14281 gttatcagtg cgaagcggcg tttggcgagg cgctaacgct ggcgccgcat ttgcgggaaa
    14341 aactgcaaat cgttaccaaa tgtggtattg cgaccaccgc cagagcggaa aataggctcg
    14401 gtcattatat taccgatcgc cgccatatta ttctgagcgc cgaacagtca ttaaaagatc
    14461 tggcgacaga ttatctggat atgttgttaa ttcaccgtcc cgatccgtta atggatgcgg
    14521 atgacgtcgc cgaggcgttt caacatctac atcaaagcgg caaagtgcgc cattttggcg
    14581 tttctaattt tacgccagcg caatttacgt tgctgcaatc gcgcctgccg ttcaccctgg
    14641 cgaccaacca ggtggagatc tcgccggttc accagccttt gttgctggac ggcacattag
    14701 atcaattaca gcaactgcgt attcgtccga tggcctggtc atgtcttggc ggcggtcgtc
    14761 tgtttaatga tgaggcttat cagccgttgc gccaggaact ttccgttatc gcgcaagaac
    14821 tcaacgctag ttctattgaa caggtggtct atgcctggat tttacgtttg ccgtcgcagc
    14881 cgctgccgat tattggctcg ggtaaaatcg aacgcgtacg cgccgcacta gaagcggaaa
    14941 cgctgtcatt gtcgcgtcaa cagtggttcc gaatccgcaa ggcggcactg ggttatgacg
    15001 tgccgtaatc gccaactcgt tgactttccg ttcatgtttt cgccagtggt ttacacttaa
    15061 caggcgacca catgtaacgg aggttttatg aagcgattaa gtttagcgat ggtgacgctg
    15121 ctggcctgtg cgggtgcgca ggctgccagc gagaaagtag agatgaatct ggtgacggcg
    15181 caaggcgtag gacagtctat cggcaccgtc gtcatcgatg aaaccgaagg cggcttaaaa
    15241 tttaccccac accttaaagc gttgccgccg ggcgagcatg gttttcacat tcatgccaaa
    15301 ggtagctgcc agcccgcgat taaagacggc aaagcggttg ccgcagaagc cgctggtggt
    15361 catctggacc cacaaaatac cggtaagcat gaaggaccgg aaggtcaggg gcatctgggc
    15421 gacctcccgg tgttagtcgt taataatgat ggtatcgcca ccgaaccggt tactgcgccg
    15481 cgtctgaagt ctcttgatga agtgaaagat aaagcgctca tgatccatgt gggcggcgat
    15541 aacatgtccg atcagccgaa accgctcggc ggcggcggaa cgcgttacgc ctgcggcgtc
    15601 attaaataac ccggagacag tgttccctgc gctggagcct gttccagctg cgacagcgaa
    15661 cagtgtaaac gccagataat cgccgccagc tcatgcgcgg cgggttgatg atgatgtgcg
    15721 agcgtgtcgc agatacgctg tagttcctgt agcgtgacgg caagcgggcg ttgctgcacg
    15781 tcgcgctcgc tcatcacatc gcgcagcagg gatatacaaa tatcccgcac ccgggaaagc
    15841 ggatcggaac gcgactccca ggcgcgcagc tgccacacca catgcgagca gttcagcagc
    15901 accactcccc aacgtaataa ccaccggcgc gccagcgcat cctgactatt gctgagctga
    15961 ctgacgtgat gataggtcag cgattcaaac tcgctttcgc tatgggaagg gtgacggcta
    16021 agctgatcga cgaaatcccg gcgtagcgcg cggatatggc ggcggctttt tacggcatcg
    16081 gaaccggggc gcaaaatcgc aaacgccagc caggaaatcg cgacgccgac gatcttggcg
    16141 gtattatcgt taaggaagtc ggcgaagtcg tacaccggtg gattggtcac ggcgatgaat
    16201 gagcccataa aaacgataag ctgcccccac agtcccgcca gcttaggcat ctgcagttta
    16261 agcagttgca tcgtgacgaa cagcggaaaa aggaaaagca agaattgcca cagatcggtg
    16321 atttgcacca tcaggccaaa tttcaccacg aagctgaata aggacagcag cactaaagta
    16381 cgcatcaata aggaaagcga cttaaacggc gtggcgacga tggagtagag gacgcaactg
    16441 atcgccgcca gggttaatgc gccgggcccg gattcccatt gcacgccaat actccaggcg
    16501 ccaatcaccg tgagcgtgca aaaggtacgc acgccgctcc agatggcctc tgcgttatcc
    16561 gtatgccgcg caaggccggg agtgcggcgg atatggattt gatccaccgg cgcgccgctt
    16621 tcgatcagat ataattgacg gctgctgcgc agatatagct ggcaaaaata gcgtaatcgc
    16681 tgccagaacg cgaggtgacg ataatcctgt tcatcctgcg ggcatagcgg cgcaataatc
    16741 cgcgccacgg tgtagctgtc cgcgcgcggt tttgccaact cagctaagag ttgttcaatg
    16801 acttcgcggc tgttttccgg cggcgtcggc cagtttaaaa gcattctacg cagactggag
    16861 atcacgctgg ttagccgtaa ttgctggtgt aacaatgcat ttagcaatgc attctgacgg
    16921 cgaaaacggt agtgactcca gaaggcctga atacgcagca ggttcatggt caggatttgc
    16981 ccaatgaccc cctcatgcgc ggagcggata gcgtcggtag tctccggctg ccacagtaga
    17041 ctggcatgtt ccagcaagcg cgcatgcatg tttttcaacg cggtgagcag ggcagtgcca
    17101 tccgatgtgc tgggtaggat catcatcatc atgccgccac agaggatgcc gacgataact
    17161 tcacatacac gtgcctgggc gatatcccac aactgcgtga tttctacaat attaaccatc
    17221 gggaacgcga tgatcgccgc cgtgtagccg gacaactgga aagcataagc ggcattattg
    17281 gtaaaatgcg cgcaggccca ggtacaaaaa ccgatccagg cggccatgct aaataagaac
    17341 aaccagggtt cattcagcgt atggccggca ataatcaacg cggcggtcgc gccgagtaaa
    17401 ctcccggcaa tacgccccag acttttactg attacgccgc ctacggtcgg aaagctcacc
    17461 actgcggccg aagtcatcgc ccagtagggc tcatccagat tgagataata agcgaatgtc
    17521 agcgcgagac acatggcaat ggtattgcgc aacgcgtaac gccactggcc ggaggtcgct
    17581 ttaaaccagg gcgtatttcg cagggccggc agggagagtt tcattaccgc tgtccaatgg
    17641 ctacgctgca ggtagtgccg gagacgagcg tgatatcctg cggcaaagcg tcaaattcga
    17701 tacgtaccgg tacgcgttgc gccagacgta cccacggtac gttgggtttg atatcgggca
    17761 ctaaaccgga gtcactttcc acgctttggt cgtaaatagc gcgcccgata ctgccaacgt
    17821 gaccctgtaa cttaacattg ccactataca gtgttattaa tgcaggctca ccttcgcgga
    17881 tatggcgtag tttggtttct tcgaaatatc ccattacata aaatgaatgg ctatctacca
    17941 gggcgaaaag tggcttaccg gtgctagcat aatcaccggt acgcgtggaa aggttggtca
    18001 cccagccgga taccggcgct tttacttccg tctggctaag ctgccactgc gcctgtttta
    18061 acgttgccag tgcgacatct acgctggcct gcatcgcttt aacattcaga ttggcgctat
    18121 ccagatcttc agcagagatg tagttacgcg ataaatgtcg acgtcgatcg gcttcattat
    18181 tcgcttttgc cagatcggac tgcgctttgg ccaactgtgc ctgcgcgtta agttctgcaa
    18241 tatggaaggg cgttttatca atgacaaaga gaacgtcccc agcgttgacg aactgattat
    18301 ctttgatatt gagttgggta atgctgccag aaacctgtgg cgttacgctg acctgttccg
    18361 cgcggatttt accatcgcgc gtccacggtg actgcatata gtaattccat aaccaccacg
    18421 cggccagaac ggcgacgacg gcgacaatga gagtagaaaa atattttatt gtttttaacg
    18481 acatatttac cacacgatca gtaaaacgag gcccagacat acgcaaagcg taaagaggga
    18541 gagatccatt aacaggggat gccagatttc atcagagtat atccggtcac gcaggagtcg
    18601 gtgaataaac aaccagataa cgaacccaag cgcaaaggct ttgaagaatg gcggaaagta
    18661 aacagatgct cccaacatga gatcttgtaa gggcaatcct gtggcgttga gtatacactt
    18721 cacaagcaat gttcctttgc gtcagacatc gatgctttag ttttagccaa aaccgaagct
    18781 acaggtgcca ggtgcgcact atgtctgaaa aaatgtctat tggtaagcaa atttagcaat
    18841 acatttgttt tgagaataca aatactgcac actattctaa aatcagcata ataacttagc
    18901 aagctaatta taaggaggtg aaattggaat cgccactagg ttctgatctg gcacggttgg
    18961 tgcgcatttg gcgtgctctg attgaccatc gcctcaagcc tctggaattg acgcagacac
    19021 attgggtcac gttgcacaat attcatcaat tgccgcctga ccagtcgcag attcaattgg
    19081 ctaaagcgat aggcattgag cagccatcgc tggtacgcac gttggatcaa cttgaagata
    19141 aggggctaat ttcgcggcaa acctgcgcca gcgatcgtcg cgctaagcgg attaaactga
    19201 ccgaaaaagc ggagccgctg atcgctgaga tggaagaggt cattcataaa acgcgcggtg
    19261 aaattttggc tgggatttct tcagaggaga ttgagcttct gattaaactt gtcgctaaac
    19321 ttgaacacaa cattatggaa ttgcactctc acgattgagg tgcaggggca tacgtgtggc
    19381 catgtgacca cacgtaaagc ctggtttagc gtggagagac agtaacctgg ctgccgttgc
    19441 tggccagcac gacacgctga cctgccgaga aacgcgtatt tccttgtttc tgcacaacca
    19501 taatggtgtt gccatcgtct ttacgaattt ccagttccac accctgggtt ttattcattg
    19561 cgctctggac gccctggccc gctacgccac cagccaccgc gcctgccgcg gtcgccagtg
    19621 aacgacccgt accgccgccg atagtgttgc cgaggaatcc gcccaacacc gcgccgccga
    19681 tagcgccaat cacgttagaa tcatcaccgc cctgaatttg aaccggacga acgttaacga
    19741 tagtaccgta cgttacattc tgaacttgtt tagcctcgga tgcggtataa acatcacccg
    19801 aaaggctatc attgttaaca cacccagcta aggataaccc catcagtgaa acggccagta
    19861 cacgtttaat catttaccca tctcctgttc ttcacgaaac gctatttcag catccctata
    19921 gctaaattat atggcattta tgcagttaag gtcatatctt ctgccgaaag aatgtaaaaa
    19981 tcataatcag aagttaatta actaatctta aacgaagtgg gaagcaagaa aagataggtt
    20041 attgatatcc gtggacggca cggcaaaaaa cgtgacgcgg gcatcgcatt gcaaaatacg
    20101 ttatgccgag tgttaaggct taacccagct taataaggaa gaggtatgaa atcgggccgt
    20161 tttattggcg ttatgtccgg gaccagcctt gatggtgtgg atgttgtact ggcggcaatt
    20221 gatgaaacca tggttgcgca acaggcaagt ctcacctggc ccattcccgt tcatctgaaa
    20281 aaaggcattc tcgatatttg ccagggacaa ccgcttacgc tctcgcaact cggccagctg
    20341 gatacccagt taggccggct ttttgcacag gcggttaatg cgctgttagc gcaacaacgt
    20401 ttgcagccgc gggatatcgt cgccattggt tgtcatgggc aaacggtctg gcatgagccg
    20461 accggcgagg ccccgcatac gctgcaaatt ggcgataata atcacatcgt cgcccatacg
    20521 gggattacag tggtcggcga ttttcggcgg cgggatattg cgctgggcgg acaaggcgcg
    20581 ccgctggtgc ccgctttcca tcacgcgctg ttgggacatc cgacggaaaa acgtatggtc
    20641 ctgaatatcg gcggcatcgc caatttatct ctgcttttcc ccggacaggc ggtgcgcggg
    20701 tacgacacgg ggccgggtaa tatgttgatg gatgcgtgga tttggcgaca atgcgcgcag
    20761 ccctacgaca aagacgcggc atgggcgaaa gaaggtcagg ttattcttcc attgctgcaa
    20821 aagatgttgc gcgatccgta ctttgctgcg tcggcgccca aaagtacagg acgcgaatat
    20881 ttcaactatg gctggttaga gcgtcatctt acggctttcc ctggcgcaga cgcgcgcgat
    20941 gtacaggcca cgctggcgga gctgacggcg gtctccatcg cccaacaggt gctgctcaat
    21001 ggcggctgcg agcggctgat ggtctgtggc ggcggaagcc ggaatccgtt agtgatggcc
    21061 cgtctggcgg cgctgttgcc cggtatcgag gtttcgacca ccgataaggc ggggatcagc
    21121 ggcgatgata tggaagcgct ggcctttgca tggcttgcct ggcgaacgct cgcgggcctg
    21181 ccgggaaatt taccttccgt gacgggggct acagaagcca gtgttttagg cgctatttac
    21241 ccggctaacc caataactca gagttaactg aatttttccc ggaccctata tcggtaaact
    21301 agcaaggtca ggaaggggcg tttgcccttc cagaagcagg agagctttcg ggatatgcct
    21361 atgaaaaaga tcgcaataat gtttttacct gtgctgctga ccggctgtag cgtttatcaa
    21421 caatttgttg aacgtatgca aacggatacg ctggaatatc agtgtgatga gaagccgctt
    21481 accgttaaag ccaataaccc gcgtgaagag gtcagttttg tttatgacaa taagctgctg
    21541 accctgaagc aaggaatctc ggcctcgggc gcgcgttata ccgacgggat ttatgttttc
    21601 tggtcgtaag gcgagagcgc cacggtctat aaacgagaca gaattgtgct taataactgt
    21661 cagttacaaa atccgaagcg ttgagatttt cagtatgggg gcgcacaata gcgccaccca
    21721 ctgattattt ctgatcaacg ccatgtctga taacaaccaa ttgcagcaga tcgcgcatct
    21781 gcgccgtgaa tacacgaaag gcggcttgcg tcgccgcgat ttacccgctg aaccgttaac
    21841 cttatttgag cgctggcttg ggcaagcgtg tgacgccaga ctggccgatc caacggcaat
    21901 ggtcgtggcg accgtagatg acaaggggca accgtaccag cgtatcgtat tgctcaaaca
    21961 ttatgatgaa aaaggcctgg tcttttatac taacctggga agccgcaagg cgcatcaaat
    22021 tgagcacaat ccgcgtatca gtctgttatt tccctggcat atgcttgaac gccaggtgat
    22081 ggtgacaggc aaagccgagc gtctctccac acttgaggtg gtgaggtatt tccacagccg
    22141 tccgcgcgac agccagatcg gcgcatgggt ctctaaacaa tccagccgca tttccgcgcg
    22201 cggtatcctc gaaagcaaat tcctggagct caagcagaag tttcaacagg gcgaagtgcc
    22261 gttacccagc ttctggggtg gttttcgcgt gagtatcgaa cagatggagt tctggcaggg
    22321 cggcgaacat cgtctgcacg atcgcttttt ataccaacgc gacgacggcg catggaaaat
    22381 cgaccgtctt gcgccctaaa gatgcaaaaa tcttgtttta agcactggtg cggatgaatc
    22441 cgccgtttta tgctatgtct ctttcgcgtc tggcgaaaag tcgtgtaccg gcaaaggtgc
    22501 agtcgtttta tacatggaga ttttgatggc aagcagtaac ttgattaaac aattgcaaga
    22561 gcgggggctg gtagcccagg tgacggacga agacgcgttg gcagagcgac tggcgcaagg
    22621 cccgatcgcg ctctattgcg gcttcgatcc taccgctgac agcttgcatt tggggcatct
    22681 ggttccattg ttatgcctga aacgcttcca gcaggcaggg cacaaacctg ttgcgctggt
    22741 aggcggcgcg accggtctga ttggcgaccc gagctttaaa gccgccgagc gtaaactgaa
    22801 cactgaagag accgttcagg agtgggtggc gaaaattcgt aaacaggttg ccccattcct
    22861 ggactttgat tgcggcgaaa actccgccat cgcggccaat aactatgact ggttcggcag
    22921 catgaatgtg ctgactttcc tgcgcgatat cggtaaacat ttttccgtta atcagatgat
    22981 caacaaagaa gcggtgaagc agcgtctgaa ccgtgacgat cagggtatct ctttcacgga
    23041 gttctcttat aacctgctac aggggtacga cttcgcttgt ctgaataaac tgcacggcgt
    23101 tgccttacag attggcggtt ctgaccagtg ggggaacatc acttccggta tcgacctgac
    23161 ccgtcgcctg caccagaatc aggtatttgg tttgaccgtt ccgctgatta ccaaagctga
    23221 cggcacgaaa ttcggtaaaa ccgaaggcgg cgctgtctgg ctggatccga agaaaaccag
    23281 tccgtacaaa ttctaccagt tctggattaa caccgcagat gccgatgttt atcgcttcct
    23341 gaaattcttc acttttatgg acattgagga gatcaatgcc ctggaagaag aagataaaaa
    23401 cagcggtaaa gcgccgcgcg cgcagtatgt actggccgag caggtgacgc gcctggttca
    23461 tggtgaagag gggctggtcg cggcgaaacg gatcactgaa tgcctgttca gcggttcact
    23521 gagcgcgctg agcgaagctg actttgagca gttggcccag gacggcgtac cgatggttga
    23581 aatggaaaaa ggcgccgacc tgatgcaggc gctggtagac gccgaactcc agccgtcacg
    23641 tggtcaggcg cgtaagacta tcgcctccaa cgctgtcact atcaatggtg aaaaacaatc
    23701 cgatcctgaa tacatcttta acgatgagga ccgtctgttt ggccgctata ccttattacg
    23761 tcgcggcaaa aagaactatt gtctgatttg ctggaaataa ggcattaagt aacagggagt
    23821 gagaaatcac tcccttattt ttgatgttca ggtaaaaaaa tgaagaatat cctcgctatc
    23881 cagtcccatg ttgttttcgg acatgcgggc aacagcgccg ccgaatttcc catgcgccgt
    23941 cttggcgcga atgtttggcc gctgaatacc gttcagtttt ctaaccacac gcaatatggt
    24001 aaatggaccg gctgtgtcat gccgcccagc catctgactg agattgtcca ggggattgcg
    24061 gacattggcc agttagcgca ctgcgacgcc gtacttagcg gttacctggg atctgccgag
    24121 cagggagaac acattctcgg tattgtgcgc caggttaaag cagcaaatcc gcaggcaaaa
    24181 tatttctgcg atcccgtgat ggggcatccg gaaaagggtt gtatcgtggc gcctggcgtc
    24241 gcagagttcc atgtgcgtta tgcgctaccc gccagcgata ttatcgcgcc taacctgatt
    24301 gaactggaaa ttctcagcaa acatagcgtg aataatgtga atgacgccgt gcaggcggcg
    24361 cgagaactga ttgctcaggg gccagaaatt gtactggtaa aacatctcgc ccgcgccggt
    24421 tacagttcag aacgctttga aatgctgctg gtgacagcgc aggaagcctg gcatattagc
    24481 cgtccgctgg tggatttcgg ctcacgtcag ccggttggcg ctacagcgag ctatccggca
    24541 acatgacatt aattcagtcc ttccgcttta agcgctgccg caacggtcgg tctttttgcg
    24601 acacgctgca tataactttc aatatgcgtt gacccgtcca tattcagttt tacgccatag
    24661 gcccaacgca atacggtaaa cagataagcg tctgcaatgg taaaacgctg gccgcaaatc
    24721 cactggtcgt ctgaaagcga ctcatccaca tactgaaatt tcttttccag accggcgcga
    24781 acggcgggtt taagtgtttc cggcgtgtca gggcggaaca gcggggtaaa gcctttatgc
    24841 agttccgttg caatatagtt gagccattcc agcgtatgat agcgagcaag actacttacc
    24901 ggcgccagaa gctggcggtc gggaacgctg tcggcgaggt actgcataat ggcgacgcct
    24961 tcagtcaaca gtgtgccgtc atccagcagc agagccggaa cctgtccttt agggttgact
    25021 gccaggtaat catcaccgtt ttccaggcgt tttttcgcga gatcgacgcc atcaagcgta
    25081 aagtctttgc caatttcgcg caggataata tgggaagcaa gagagcaggc acccggtttg
    25141 tagaacagtt tcatcggtaa ctcctttttg ctgaggttta aagtatggta gtgcggggac
    25201 gagcaaaaaa aaagccgcta acgcacagtt agcggcctga atgttgtttc ccggaaaatt
    25261 aaactgtagc ggctttagag cctttttcag cggtatcatc gtcctgggtc atacggttca
    25321 gcttaggcgc tgtcagcagc atcaggacgg cgataacggc ggttgctatg ccaatctgca
    25381 taaatacgcg accatagact tctagggaca tcagtgggtc agtcacgtcg ctcggcacag
    25441 ccatcaggtt ggcgacataa ccgccgatga tgttagcgcc tgccgttgtc aggaaccagc
    25501 tacccatgat gaagcccatc agacgctgcg gaaccaactg tgcgaccatt gccaggccca
    25561 gaccggagat catcagctca ccgatacttt gcaggccgta gcttgcgatc agccagttta
    25621 cggatacgat gccggcatcg ttcgcaaatt tggcgcccag cggcagaatc aggaacgcgc
    25681 cggaacacag caccatacca atggcgaatt tcatcggcat cggcagcgta tcgcccatcc
    25741 tgttataaat agcggccaga atcgggctgc cggtaatgat ccagaatggg ttcagcgcct
    25801 gatactgttc cggttcgaac gcgataccga gaatagagtg ctcgacgtta cgaatggcaa
    25861 agaagttcag cgacgtcggc atctggctgt acagtacgaa gaagataatc gcctgcagca
    25921 tcaaaataaa ggcgacgatc attttacggc gagccgcgcc gtgcatggaa aacgcttctt
    25981 taccgaaaat aatgacgatg ccaagagcga ttacgcccag caccatacgc gcgatatcct
    26041 ggttgtgcag cagccaggtg gcgaccgcaa tcagaacgac aatacccacg attgtcagca
    26101 gcagattacg gaagttgatc ggttcaaagt cgggtttgga accgtagctt ttcacccagc
    26161 gctggcagaa agcaaagtta acgacggtta tcagcatacc gacgacgcta agcgcaaacg
    26221 cggtgctcca gccataacgc gccgccagcc acggcgtcgc cagcatagag aagaaggagc
    26281 cgatgttgac ggacatataa tacatcgtaa atgcgccgtc gagacgcgga tcgtccttcg
    26341 cgtaacaggt agacagcagg gaagacgggt tagctttaaa cagaccatta cccacagcga
    26401 tagccgccat gcccatatag acgatgccag cgtcatgacc agaccatgcg accagcgcat
    26461 aaccgatagc cagcaccacg gcacccagca taataacgcg tttggtgccc agaattttat
    26521 cacctaacca accgccaatg gcgaccaggc cgtacaccag cgcactgaag gaagagaaaa
    26581 gggtgatgga atccgcttct gacataccca gttgttttac caggtagacg gccataatgc
    26641 cttgcaggcc gtaataacca aaacgctccc ataactctat cgagaagatt agatagaacg
    26701 ccttcggttg tttgaaagcg ttcaaactga cgctttcagt tggttttttg tttgcagtag
    26761 acacttttac ctctttttta cgccccgtat taacagggat tgtctggcgc gtgatgagtc
    26821 agactcatcc gtccgattgt tatattggag gggaaacggc aggtaatgtt cactatcttt
    26881 cctctccaga caagagcttt gtaataatct gttacatata actcttctgg ttgaatcgtc
    26941 cgatgtcaga aatgttatcc agcgttaaat ttcttcattt gaagaatggc agatttttac
    27001 actgcaaaaa ggccattagt ttggataaaa ggcgatatct tctgctattt aaggtgaaaa
    27061 gcagtgatat aggccattat ctgaaaaaat ggcagagtaa tgttttgtag tgaaaacggg
    27121 gcgtcagtct atccggttgt aaatgtaacc ttaggtgtca ttaaatttca catgaagtta
    27181 tcaaagtgat cctgatcacg gatagataga aatttttgcg attaaaaaat gattaacctg
    27241 acgtggaggg aaaacgaaag cacattacat cagaaaaagg acagagactg gaatgattga
    27301 tggctaaaat agatccaggc cgaaggtggg agcgcgctgg tatgacgggc gcactccgac
    27361 catatcaaat atcgactttt tctttgtatt cgcaaaggtc ttcaatgagg caggagccgc
    27421 agcggggttt tcgggcgata caggtatagc ggccatgcaa aattaaccag tgatggcagt
    27481 ccactttgaa ctcattcggc accactttca gtaacttctc ttctacctgc tcgacatttt
    27541 tacccggcgc gaactgtgtt cggttgcata cacgaaatat atgcgtatca acggcgatgg
    27601 tcggccagcc gaaggcggta tttagcacca cgttagcggt tttacgcccc acgccgggaa
    27661 gcgcttccag cgccgcccga tcctccggca cttcgccatt atgcttgtcc attaaaatac
    27721 ggcaggtctt aatcacgttt tccgctttac tgttaaataa gccgatggtt ttgatatagg
    27781 atttcacgcc ttctacgccc agttccagca tcgcggctgg cgtattggcg gccgggtaaa
    27841 gtttggcggt cgccttgttc acgctgacgt cggttgcctg cgcggaaagc aacacggcaa
    27901 tcagcaactc aaacggcgac gtgaaattga gttccgttgt ggggtgcgga ttgctgtcgc
    27961 gcaggcgcgt cagaatttcc agcctttttg ctttgttcat cagactttcc ctgtttcacc
    28021 ggccggaaca gcggaaggcg cggtttcggc gcggcgtttc ttcatttttt catcaataag
    28081 atattttacc gccagcatga gtcccagacc gataaacgcg cctggcggca gcatcgccag
    28141 caggaaaggc gagtcggtgt gaaatatctc gacccgtaat acttttgccc agcctcccag
    28201 caggctatcc gcgccatcga aaagcgtacc attcccgagg atctcgcgca gtgagcccag
    28261 cacgaacatc gcgcctgtcg cgcccatgcc gatggaaaaa ccgtccaacg cggaaagcca
    28321 cggtcctttt ttcgcggcaa acgcttcggc gcgaccaaca actatgcagt tcgttacaat
    28381 cagcggaata aaaatcccta aagactgata cagaccgaac gcatacgcat tgatcagcat
    28441 ctgtactgcg ctgaccaccg aagcaatgat cataacgtaa atcgggatac ggatttctgc
    28501 cggcgtccag cgacgtagtg cggacaccgt aaggttggtc agcgttaata ccagcgttgt
    28561 ggcgagaccc agccccagag cgttggttgc cgtagacgtc actgccagta aagggcacag
    28621 gccaagtagc tgcaccagag cagagttatt tttccataac ccctgaacaa caatgtcttt
    28681 tatttcgctc atggctattc tccacaggcg gttaaatggg ggagctgagc gggcagtgat
    28741 tcggcgtaca gcccggcgcg tttaaccgca ttcactacgg cgcgcggcgt tattgtcgcc
    28801 ccggtaaatt gatcaaaatc accgccatct tttttcaccg cccagtgcgt atcattttca
    28861 ccgctgatgg ttttaccgct aaagtgggta atccagtcag acaaacggcg ctcaatttta
    28921 tcacctaacc ctggcgtctc atgatgttcc gtcacgcgcg tccccaggat agtaccgttg
    28981 aaatctgcgc caacaataag ctggatagcg ccggaatagc catctggcgc ggtggcctca
    29041 atgatggccg ctacgggttt atcatccttg cgagcgataa aaacacggtg tgtgcctttg
    29101 ccgagggcgg gcgcatcgac cagataacag ctctcttgca gattattatt gtaacgatct
    29161 ggcggcaata cctgatcgaa cagggcatgt tgttgttgca gcgcttgttc gtggatggtt
    29221 gattttgtca tctgattaat caccgcggtc aatcccgtag agcctgcggc aaaaagcgcc
    29281 agcgtaatac cgtgtttacg aatcgttttc agcatggttt atcctttgcg atgtccatag
    29341 acgcgggggc gcgtgtagta gtcgatcaga ggaaccgtga tattcgccaa caggacagca
    29401 aaagcaacgc cgtccggata gccgccgaag ctacgaatca gccacactaa taccccagcc
    29461 agcgcgccga aaattaaacg tccacggttg gtcgtggagg cggtaaccgg atccgtcaag
    29521 ataaaaaatg cgcccagcat ggtggcgcct gacagcagat gaagctgcgg cgaggccagc
    29581 gtagcgggcg agaaaagcca acctaacgcg gcgcatagcg ccagcgtgag cagaaaactg
    29641 accgggatat gccagcggat ggctttttgc cacagcagga atacgccgcc gacaagccag
    29701 gcgaggttaa cccactgcca gcccacgcca gccagcgcac cgctgtatat cgggtactgc
    29761 atgatttgct caacggagtg cccggcgcgc aaggacgttt taaacgtatc cagcggcgtc
    29821 gcctggctga taccgtcaat accgatacgt agtagcgtca tatcgccgcc gctggcggta
    29881 tgcccgctaa aaatcatccg taacgtgtcc agtatatcgg gcgttgttgc ggctatttca
    29941 taaggcggca accagcttgt catttgcacc ggaaaggaaa ttaatagcac cacgtagccg
    30001 atcatggccg gattaaaggg gttttgtccc agcccgccat ataactgttt agcgataata
    30061 atggcgaatc cggttcccag cacgaccatc caccagggcg cgagcggagg gatgctgacc
    30121 gccagcaaaa gccccgtcaa taacgcggaa taatcctgca ggtgactggc gaccgattgt
    30181 ttgcgcagtc taaggacaat ggcttccgcg acgagcgccg tgatagcagc cagaacgatc
    30241 tggaaaagcg ttccccaacc aaaaaaccac gtctgcgcgg caatccccgg cagagcggcg
    30301 attaatacca gcaacatgat tcgcgatgtc tggcgctggt tatgggtata aggcgagctt
    30361 gcgattctga ataccattta atcctcgtta acaacctgct gctgtgctgc tttttttgcc
    30421 tgaacgcgag cgatagccgc agcaaccgcg gctttacgcg ggtcggccgg ttcgacaggt
    30481 tcgcttacgg tctgctgctc ctgcttacgg gctttggcac gggcgatcgc cgcttccacc
    30541 gcggctttac gcggatcgac cggttcggcg ggttcgcttc cggcctgctg ctcctgtttg
    30601 cgggctttgg cgcgggcgat agccgcttcc accgcggctt tacgcgggtc gaccggctcg
    30661 gcaggttcgc ttccggcctg ctgctcctgc ttacgagctt tggcgcgggc gatagccgct
    30721 tccactgcgg ctttacgcgg atcgtcgccg gatatcgcgc tgtcagccat cggatgagcg
    30781 gcttgtttag cgcgcgcttg cgctttacgc gcttcacggg ccgcgatgac ggcgctattg
    30841 tctggcagac tacccgcctg aataaccacc ggttgcgtgg cctgcgcctg tttctctttt
    30901 acccgcgcca gcgcagcggc aatggcatcc tgatcttttg ccgctggttg taccgctgcg
    30961 ctcttgtgac gtgcaaggcg ggcggctttt tcgcgctcca gtcttgcctg acgagcctca
    31021 aaacgcgctt tggcttcggc ggcgcgtttt tcttcaagcc tgatcgcatt aatctccgct
    31081 ttttcctgac ggaaatattg gacgagcgga atattactcg ggcagaccca ggcgcaggcg
    31141 ccgcattcta tacaatcagc aatatggtga gcggtagcct tgtcatgctg ctgccctttg
    31201 ctgaaccaat aaagctgctg cggtaaaagg tcggcagggc aggcgtcagc gcaagcgctg
    31261 caacgaatac agcttttctc ttcctgaggc gcccccattt cagtcacgga tggcgccagc
    31321 aggcagttgg tgatttttac gaccggtacg tcaagccagg gaagggtgaa tcccatcaac
    31381 gggccgccca tgatgaccat ctggtcagca gaggggcaga acccggcatc gttaagcaaa
    31441 tgacgaacgg gagtgccgag ccgcgcccag acgttacccg gacggcttat cgcttcaccc
    31501 gttaaggtga cgacgcgttc tgtgatcggt tcgccgtcaa ccacggcgcg tttcacggca
    31561 tatgccgtac cgacgttttg catcagcacg ccaatatcag aggagcgccc gccgtgggga
    31621 acctgttttc ccgtcagtat ttgggtgagc tgttttgcgc cgccggaagg gtatttggtc
    31681 gggataacac gtaatgaaat atcatgagcg tcagccagta cggcgcgcag catggaaata
    31741 gcctgcggtt tgttatcttc aatgccgatt aatacctcac gcggttgcag aatatgcgcc
    31801 aggatgcgaa taccttccac aatctgcgcg gcgcagtcct gcatcagacg atcgtccgcc
    31861 gtaatgtaag gttcgcactc tgcggcattg ataataagcg tggtgatttt atcgtcgccg
    31921 ccctgcaatt taacgccggt gggaaaccct gcgccgccaa gcccggcaac gccatactga
    31981 tgaatgcgtt caatgagcgc ttcacggctg tgggcgcggt aatcagacca gccctcgcgt
    32041 tcaatccagc ggtcctcgcc gtcggcatca atgatgacgc ttaactccgc cagcgccgaa
    32101 ggatgcgccg tcgagtgggg cgcaatagcg ataaccgtcc cggaggtggg cgcgtgtacc
    32161 ggcagcattc tcccacgtcc acgggtaagc gcctggccgc gtagcacgcg atcgccgacg
    32221 ctaacgcaca gctcgccctc agcgccaatg tgctgtttta aagggataac aaagcgcggc
    32281 gccaaaggca cctggcgcag cggcgtgccg tttgactggg acttcatttc gggcggatga
    32341 ataccaccgt cgaaatccca gattttatct tttctgaaag cggaaaatag tttaagcatg
    32401 ttgttccacg ggaatgatgc gaacgggaat ggtgttcaaa tcccatttcc aactgtcggg
    32461 cgtctcattc accggacgta attcgatgca gtgcgtcgga cacggatcga cgcacagatt
    32521 acagccagta cagagatcgc tcatgaccgt gtgcatggcg cgcgttgcgc caacgatggc
    32581 gtcaaccggg caggcctgaa tgcattttgt gcagccaatg cagttatttt catcaataac
    32641 tgccagcata cgtactggcg cggcctgctg ttcttcacca tcgcatggtt gcggctctac
    32701 gtttagcaac tctgccattt tcagcatgac ggcttcgccg ccgggcgcgc aacgattgat
    32761 tttctcgccc tggagaccca cggcttcggc gtaggggcga cagccgggat agccgcactg
    32821 accacactga ctctgcggca aaatcgcatc gattttttca acaaccggat catcttcaac
    32881 cgcgaatcgg cgggaggcat aacccagaat ggcgccgaac accagaccca gaagggtcag
    32941 ggcgccaacg gcaatccaga tagtattcat tacaacttca ccaaaccact aaagcccata
    33001 aaggccaaag acattaatcc tgcggtaatc aatgctatcg cgttaccacg aaaaggggcg
    33061 ggcacatccg ccacggcaag gcgttcgcgg atagcggcaa acagaaccat cactaatgaa
    33121 aaaccgacgg cggcggaaaa tccgtacagc gccgactgaa gaaagtgatg accgagatta
    33181 atattcagta acgctacgcc cagaaccgca cagttagtgg taatcagtgg taagaagatg
    33241 cctaacaagc ggtataacgc cgggctggtt ttccgcacaa ccatttcggt aaattgcacg
    33301 accacagcaa tgacgaggat aaaggccagc gtccgcagat aaatcagatc cagcggaata
    33361 agtatccagg tgtcgataag ccaggcgcat atcgacgcca gcgtcatgac aaaggtcgtc
    33421 gcgaggccca tccccatggc ggtttccagt tttttggata cgcccataaa gggacaaagg
    33481 cccaggaatt tgaccagtac aaagttattg accagtacag ttccgacaaa gagcagcagg
    33541 taatcagtca tgtttcggcc tgaaataaaa aagccgccta ttatctgtca aactaccaca
    33601 ggcgacaaca ggttaactgt agggttatta cggattaaca aacgttgttt taacgcgcgc
    33661 tgaacgtttg agataaggca caatgagcgc cgtcgccaac agtgggaaga gtaactgacg
    33721 cacggcaaag gcatctgaga cgggcgaaaa ggcaaatgct ttaaccgcca gtaacaccga
    33781 caccagcagc cagataatgt aatgctttgg cacgcagcgt ctgcgcttga agaatgcgat
    33841 cgtcaaccac aaggtatagt accacatggc gatagcggta ataaatgaaa tgccccatag
    33901 cagtaaatta ccggtttcct gtccgctaag cgttttgaac gtttgcggtg tggcaagcgc
    33961 cataacgtag agtaataacg ccagcgaggc gctcaacaac gcgactaaca gccaggctaa
    34021 cgggccaaga agccagcctc caattcgttg tggcggtgtt gtagtcatat cttctccggg
    34081 gttacgcgcg ttaacggtca tgccgctcat tttggggcaa atattataag gtttttgatg
    34141 ttaaacgcta ctttctttat tgcacatagc gccagacgga ttgcggaacc tgacctacat
    34201 caaacaggcg tcctccggaa accagctcgg cacggcggtg atctgcagcg cgatacatat
    34261 taacgatgtc catgtcatca gtaagggtat agttaaggtg gtcgaacagt ttttccagac
    34321 tttcgagcga actaattttg cggaatttta atagataatc ctgaacagtc atataaagtt
    34381 gatccatatt aaatataatg ccaacggagt agtcactgat aaaaaaataa acaaaattgc
    34441 accagtgaga ggtcaggggt gcaggtaaaa agggaatatt cttaccggta aagagtcagg
    34501 cgccacatgg cgcctggggc gaaaggttaa cgcgctttac tacaacaggc aataaacgtc
    34561 agaccagata gaacatattt cgtttttttt gccggttttt gacttttctt tgcacgcccc
    34621 ggggcgctgc ttaccgtacc gcgcgaaaat gcctttacat tatctgacgc ttacttcttc
    34681 tgaacggaag ccgtgggctc aggtggttgg taattgtcaa tatggttggc aatacctaaa
    34741 agaatgactg agataatgag aactatccac ccagttaatt caataagacg attcattatt
    34801 gacgacattt gctttgattt atccataaac acagagagta aatgttactt tcctggcgaa
    34861 cggtcggcaa gagggagggg aacgatttca gcctctgttc tgtaacaagt taatcatttg
    34921 atgctacgtt gatggtcagg acgctattgc ggctagtcgc acgatggtgt ggaatagcga
    34981 tatctaaaac cggaggcagt gagatgaatg acaaaatccg cgttgggtta atcggttatg
    35041 gctacgccag taaaaccttt catgcgccct taattatggg aacgccaggg ttagagcttg
    35101 cggcggtatc cagcagcgat gaaacaaaag tgaaagcaga ctggccggcg gtctccgtgg
    35161 tctctgagcc ccgacattta tttaacgatc cgcatatcga cctgatcgtg atcccgacgc
    35221 ccaacgatac ccatttcccg ctggcgaaag ctgcgctgga agccggtaag catgtggtgg
    35281 ttgataaacc ctttaccgtg acactgtcac aggcgcgaga attggatgcg cttgcgcgga
    35341 gcactggtcg ggtactttcc gtcttccaca accgacgctg ggacagcgat tttttgacgc
    35401 tgaaggcctt gctggcggat ggcgtgctcg gcgaggtgtc cttgtttgaa tcccactttg
    35461 atcgcttccg tccccaggtg cgcgaccgct ggcgcgagca aggcgggccg ggaagtggta
    35521 tctggtacga tctggcgccg cacttgttgg atcaggccat tcaacttttt ggcctgccgg
    35581 tcagcatgac ggtggattta gcgcaactgc gtccgggcgc gcaatctaca gattatttcc
    35641 acgcgatttt atcctacccc cagcgccgcg tgattttgca cggtacgatg ctggccgcgg
    35701 cggaatccgc gcgatacatc gttcatggtt cgcgcggtag ctatgttaaa tatggcctcg
    35761 atccccagga agaacggtta aaaaacggcg agcgtttacc gcaggaagac tggggatacg
    35821 acatgcgtga cggcgtattg accctggttg agggagagac gcgcaaagaa gagaactggc
    35881 ttacgttgcc gggtaactat ccggcatatt atgccgccat ccgcgatgcg ttaaacggta
    35941 acggtgaaaa tcccgtgccg gcaagccagg cgattcaaat tatggagttg attgaactgg
    36001 gcatggaatc ggcaaaacat cgcgcgacgc tgtgtcttgc ctgagatgtc gcatttctcc
    36061 gcctgggata gcattaaacc gcaggcggag aagagcgtta gtgtcaataa agcaatctta
    36121 cgccgcggcc actttttcgc gtagcgcacg tttttcgcta tcgctcagaa aggcgatttc
    36181 cagaccgtta atctgcgcct ggcgaatctg ttcgcggctc aatcctgccg ctggcgcggc
    36241 gacgtgatat tcatggataa tatctacgcc ctgaacagcc ggatcgtccg tattaagact
    36301 ggcgagaacg ccatgctcaa ggaaggtttt tagtggatga tccgccagcg atgcgacggt
    36361 actggtctga atattcgagg tcagacagga ttcaataccg atacgctgct gtgcaagaaa
    36421 atccattaac gcgcgatctt cgacagcttt tacgccatgt ccgatacgct cggcccccag
    36481 ttcgcgaatc gcctgccaga tactttccgg ccctgcggct tcgccagcgt gaacggtaat
    36541 atgccagccc gcatcgcgcg cccgattaaa gtgcgacaaa aacagactgc cgggaaagcc
    36601 aagctcatca ccggctaaat ccagcgcggt gattttctct ctgtgcgcca gcagcgcatc
    36661 aagctcctgt aaacatgccg cctcgccgaa ggtacggctc ataatgccaa tgagtcgtgc
    36721 ctcgacgcca aacgtgttac agccgtcgcg tacaccgtcg ataacggctt caaccacgcc
    36781 tgcgatcggt aactgatgcg ccatcgccat atagccgggc gaaaagcgaa gctcgacgta
    36841 atgcaggccg ttacgtgccg catcttcaat attttcaaag gccacacggc ggcaggcgtc
    36901 aagcgatgcc aggactttta ccccccaatc gagtttagtg agaaagctta ctaaatcggg
    36961 ttcggttgag gtgacctgga catgcggaat cagcgtttcc agcgtttggg cgggaagggc
    37021 gatgttgaac tgccgaccaa gatccagaat tgtttgggcg cgaatgttgc catcaaggtg
    37081 gcggtggatg tcagtcaaag gaagcgtaat atcaatcatg ggcgcactca atttttaata
    37141 aaagtgcgca ccattatact acagattgat aatgctctgg aaattttgca aaaacggagt
    37201 cattacgttg caacttcgcg agagcgcggg agaaattttg tatcattctc tgtaacgcgc
    37261 ccccggtcag ctcacggggg ttgtctctgt tatcgcctct caggataaag ggtcaacccc
    37321 ccgcttgtag acggtatcag cgaacggcgc ggtggcaaaa tccatatccg agatcgtaaa
    37381 ggggagcaga tcggcttcgc caaaacgatc ggcgacataa tcccactacg tacaccatgt
    37441 cccgcgtcgg tcaacttcct gtgaaaaatc gaacatatcc cttccttatg cctgaacggt
    37501 attcatcagg ccaaccattt catcttttac cgactgaacc tgcgggccga taattacctg
    37561 caaattatgc tgattgagct gtacgatgcc tgtcgcgtga ttgtccttca atgcctggac
    37621 atcgacaaac gacatatctt tcactgacag gcgtaggggg ggatgcagtt gtccagactc
    37681 acgatgtttt ccgtgccgcc taatgctcac gacgagcacc atgtgcggag tcaaacgata
    37741 gccgctcgcc tggtaacgca aaagtagagg ctgcgcgtcg ttcggcgcag accgggtgca
    37801 gcgtcgcgac acccggcaag gcgattattg ttgaggcagc gccggaacgt ccggaacgga
    37861 aagcgccggc atcccaaata ggccgacaaa gtcttccaac ggcatttttt gtccgttgag
    37921 cgtgatctgg ccattggcgt actgcaaact ggaggcgata gtattatcct tcagcgttgt
    37981 cagtcggaac atctgaccca ttgcggacag cccctgcacc tgctgttttg ccagtttttc
    38041 cgcatcatcc tgctgatagc cttccagttt tgctatctgc gtcataaact cgaccgccat
    38101 gtccatcgga attgccagtt tcgcatccag cgatttcacg gagcggtcga cttcctgtgc
    38161 cagcgtttgc ggttgtgccg ttgtggttgc cggatctttg aggaacagcg acagattcag
    38221 cgtggtttcc cctttggcgt ttttccagct aagcggcgcc agggtcagaa ccggatcgcc
    38281 ttttaacagc acggggagag cgctaaagaa cgcttcagtg actttttgct gataaagctc
    38341 aggattctgc gccacgtccg gctgattcag cagcgcctgc gtttgcgcat gatattgctg
    38401 actaaactgg tgccaggctt cgccgtcgat ttgaccgact ttcagcgtta atttaccgct
    38461 gcccaaatcc tgattctgca ctttcaggct gttaagcgag taatccaact ggctgttaat
    38521 ggtttttccg tcgttgacga gatcggactt gccggcaatt tccatccctt ccagcaccgc
    38581 catctcttta ccctcaatgg cgatggacag tttatccagc gttaactttt ggtcgcctac
    38641 acgctcgcca aagcttgcca gcttactggt accgtctgtt ttcaaattat taaaggtgag
    38701 ttgtaccttc tgattatatt cgttaacggc atcgaccagg ccgctctgcg cttcgcccga
    38761 cagcgaaacc acattaccgt ctttatcggc gttaagctgg aactcgccgc cgctaaaggc
    38821 gaccttttca ccggcattct cgtagtttaa cggcttgaga gagatatcgg agcgggtatc
    38881 gccgccataa ccaatgcggg tattgataac aaagggcgcg tcgcctttcg caatatcaaa
    38941 gaggggtttt gccgcatcgt tattcaccag agtggttttt accgacgcca tagaagggat
    39001 cagattgagc gttttgagct gggcgagcgg gaaggggcca tgtgaaacgg actcgtccag
    39061 cacaatgctt tgcccgggct tcaaccaggt attgtctgcg ccggcaaccg gtttgacaac
    39121 cagttgcaga tggctactga acacgccgcg ctggtagttt tgataactta attcgacacc
    39181 ggcctccggc gcagtacgct tgagctgttc attggcctga gtcaccattt ctgcaagatg
    39241 gttctccagc tttttccccg tataccaggc gccgcctgtc cagacgatgc caagtgcaat
    39301 tactacacct gcagctacca gtgttttttt catatcaatt gtccataaaa atgaaaccag
    39361 gcggattaaa ccgcctggag gagttttacg tctgttataa gcttagcaag agttgttaaa
    39421 aaattcagta cgttgctaca gcttgttata aacacgcgct aaacggcccg tgccgctggc
    39481 gttaaccgga gactcatccg cgccgataaa ggcagattca cccggcttca gtaccagacg
    39541 ctgttcatct ttacgtaaca ccgcctcacc ctcaacgcag aacagaatcg cggcgctgtg
    39601 ttggccgatg ctcgtctcct gaagcgccag gtcgtgcagt gaaaaagcaa aatcgtcaac
    39661 cggaattggg aagtccagct ccgcgccgct tttcaccggg gcagtcagca actcgccggc
    39721 aggcttaggt tcgaacttca cgttcgcgac cagctcaggg atgtcgatat attttggcgt
    39781 aaggccagcg cgcagaacgt tatcggagtt cgccatgact tccagcgcaa cgccctgcag
    39841 ataagcatga ggcgtttcgg caaacaggaa catcgcctcg ccgggattca gtttgaccac
    39901 attcagcaac aaaggagaga aaagcccgct gtcgtcagga taatactctg aaatcacgcg
    39961 gatcgtttgc cacggttcgc cttgctggct gttaagcgcc gctttgagta cggctaacgc
    40021 gcgggatttt tcttcgcctt gcatattcaa caggctggcg aaaagctggc tcagacgttc
    40081 agcattcggc gcctgcaaaa agtgggcgat agcggaatgc gcgccggcga caggttgcag
    40141 taaagagaca atgtcagaaa attcgcggaa cgcgttcatc gccaggaaag gcgccagggc
    40201 aaaaaccagc tctggtttat ggttaggatc tttatagttc cgctctgcgg catccatggg
    40261 gatacccgcc gcattttctt tcgcgaaacc gatttcggaa ttgcgcttat tcgggtgcac
    40321 ctgaatagag agcggctgcg cggcgcacag tactttaaac agaaacggca gttcgccgaa
    40381 acggttggct accgcttcgc ccagcatggc ggttttattc ttttcgatgg cgtcacgcag
    40441 ggagacggtt tcgccgttgg cggtggtgat tcgcgagctg cttttgggat gcgcgcccat
    40501 ccagagttca gccattggct gctgctgcgg attggcgatg ccataaagtt ccgttaacgc
    40561 agttttactt ccccaggcat agttttgcac tgagttaatg agtttttgca ttatcaagcc
    40621 ctgtttcaat gtggagatca atgggaggta ttaaaccaag aaacccgcat gaagtaacct
    40681 ccgggcgtaa aaagtcgtac ttgtctcagt ttttgttaaa aaattgtgta ggatagtgta
    40741 actcgctttg agtcgggcaa tggaacacct gcccagagaa taaccatacc gagcggtaag
    40801 tgagagcaca atgtcaaaca aacccttctt ttatcaagac ccttttcccc tcaaaaagga
    40861 cgataccgag tactacttgt tgaccagcga acatgtttcc gtcgccgagt tcgaaggaca
    40921 agagatcctg aaagtcgcgc cggaagcgct aacgttgttg gcgcgtcagg ccttccacga
    40981 tgcgtctttt atgctacgtc ccgcgcatca gcagcaggtg gcggatattc tgcgcgatcc
    41041 gcaggccagt gaaaacgaca aatatgtcgc gctgcaattc ctgcgaaact ccgatatcgc
    41101 ggccaagggc gtgttgccca cctgccagga taccggtacg gccattattg tcggcaaaaa
    41161 aggccaacgc gtctggactg gtggaggtga tgaagcggcg ctggctcgcg gcgtatataa
    41221 cacctatatc gaagataacc tgcgctattc gcagaacgcg gcgctggata tgtacaaaga
    41281 ggtcaatacc ggtactaacc tgccggcgca gatcgatctc tacagcgtcg atggcgatga
    41341 atataaattc ctctgtatcg ctaaaggcgg cggttcggcg aataaaacct acctctatca
    41401 ggagacaaaa gcgctactga cgccgggtaa gctcaaaaat tatctcgtcg ataagatgcg
    41461 tacgctgggc accgccgcct gtccgccgta tcacattgcg tttgtcattg gcggtacctc
    41521 ggcggaagcg aacctgaaga ccgttaagct ggcctcggca aaatactatg atgcgctacc
    41581 gaccgaaggc aatgaacacg ggcaggcctt ccgcgatatt gagctggaaa aagaattgtt
    41641 gcttgaggcg caaaatcttg gcttaggcgc gcagttcggc ggcaaatatt tcgctcacga
    41701 tattcgtgtc atccgattgc cgcgccatgg ggcatcgtgt ccggtaggta tgggcgtgtc
    41761 ctgctccgcg gatcgaaaca ttaaagcgaa gatcaaccgg gaagggttct ggatcgagaa
    41821 gctggagcgc aatcccggta aatatattcc agaggcgctg cgccaggcgg gagagggcga
    41881 ggcggtgcgc gttgatctta accgtcccat gagcgagata ctgcaacaac tgtcgcagta
    41941 tccggtatca acgcgcttgt cgctgaacgg cacgattatt gtgggccgcg atatcgcgca
    42001 cgctaaactg aaagaacgga tggacagagg cgaaggtttg ccgcagtaca tcaaagatca
    42061 tcctatctat tatgcggggc cggcaaaaac gccggaaggg tacgcctccg ggtcgcttgg
    42121 gccgactacc gcaggacgga tggactctta tgttgatcag ctccagtcgc agggcggcag
    42181 tatgatcatg ctggcgaaag gcaaccgcag ccagcaggtg accgatgcct gtaagaaaca
    42241 tggcggcttc tacctgggca gtatcggcgg cccggcagcc gttctggcgc agggcagtat
    42301 caagcgcctg gagtgtgtgg aatatcctga actgggtatg gaggctatct ggaaaattga
    42361 agtggaggat tttccggcct ttattctggt ggatgataaa ggtaacgatt tcttccagca
    42421 gattcagtca tcgcagtgcg cgcgctgcgt taagtaatgt cgccgccctg cggggcggta
    42481 acatgattcg ctattttgcc ggagaacggc gcaagcgcct tatccggtct acaccgttgt
    42541 gttgttatcg ttaatactca taagaccgca aacatgtgag caatgtcgac acatgatctc
    42601 atcaacttga gtaaggagca ggtaatggta acggtacgcc gcgagaaaga ttcaatgggc
    42661 gtgattgaag tcccggcaga taaactgtgg ggggcgcaaa cgcaacgttc gctggagcat
    42721 tttcggattt ccacggagaa aatgcccgtc tcgctcattc acgctctggc gttgaccaag
    42781 cgcgccgctg cgaaggtcaa ccaggactta gggttgttgg cggcggaaaa agccagcgcg
    42841 attatcgagg cagctgatga agtgctggcg ggaaaacatg ctgatgagtt tccgctggcg
    42901 atttggcaga ccgggtccgg tacgcaaagc aacatgaata tgaatgaagt gttagcgaac
    42961 cgcgccagtg aaattttggg cggcgttcgc ggtatggaac gcaaagtgca tcccaatgat
    43021 gacgtcaata agagtcaaag ctcaaacgat gtgttcccaa ccgccatgca cgtggcggcg
    43081 ttactggcgt tacgcgaaca ccttatcccg caattatccg cattaacgga tacgcttcgc
    43141 gataaatccc acgctttcgc cgatattgtc aaaattgggc gtactcacct gcaggacgcg
    43201 acgccgctca ccttaggcca ggagatttcc ggttgggtag ccatgctgga acataacctc
    43261 agacacattg agcacagttt accgcacgtc gcggaactgg cgctcggcgg aaccgcagta
    43321 gggacagggc ttaataccca cccggaatat gcccggcgcg tggccgagga actggcgacc
    43381 attaccgcgg cgccgtttgt taccgccccg aataaattcg aagcgctggc gacctgtgac
    43441 gcgttggtac aggcgcatgg cgcattaaaa ggactggcgg cctcgctgat gaaaatcgcc
    43501 aacgatgttc gctggctggc atccggcccg cgctgcggca ttggcgagat tgctatcccg
    43561 gagaatgagc caggcagttc cattatgcct ggtaaagtga acccgaccca gtgtgaagcg
    43621 gtaacgatgc tatgttgcca ggtaatgggt aacgatgtgg ccatcaatat ggggggcgca
    43681 tcgggcaact ttgagctcaa cgtctatcgt ccgatggtta ttcataattt tctgcaaacg
    43741 gtgcgcctgc tggccgatgg catggcgagt ttcaatcaac actgtgcgtc aggaatcgag
    43801 ccaaaccgcg agcgtattac gcagttgctg aatgagtcgc tgatgctggt cactgcgctc
    43861 aatacgcaca tcggttacga taaagcggcg gagattgcga agaaggcgca taaagaaggg
    43921 ctgacgctca aagcctcagc cgtggcatta ggatacctta gcgacgcgga gttcgacgcc
    43981 tgggtacgtc cggagttaat ggttggcagt atgacgccgg gacgttaatc cgccacatac
    44041 aggtgcagtc gcggaataat cagtcgcagc ggctgcgcct gtggtttaaa acggtgctga
    44101 atattatcgg cgtcatagtt ttccagcccg ccaatatccg gcacgccagc gccgttgtcc
    44161 gtgttgatta atgcgataat cggcgagggg caggcgtgtt gcacctgttt ctgctggcct
    44221 ttataccaga tgcgggcgat cggctgtacc ttaaccgggc gcttaatctt gagtttggcc
    44281 tgctgcggta aggcagcgat atcctgatat tcccgttcca gcttgaattg ccattgttcg
    44341 cgcgtccacg gcgggacgct gcgcggcgac gcgaggcttt ttttcaactg gctcagaacc
    44401 tcatcccggc ttaaattttt aataatatgt ttatttgccc aaccgaaacg tatggtggcg
    44461 gggttattga taagcgtcag cgtgcggtaa gcgttcagcg taattaagcc gggtagatgc
    44521 cgatgcaccc actcaaaacg tgccgctgag ggaagaccgg actctaccgt aaccatctgc
    44581 tcgaaggtgg ttttcaactg gttaatgcgc tgtacctgat tttccagatc taactgtgtc
    44641 gcattatcca cttgatagca taaaacgcca ggcaggcgga cggcggcttt actgctgcgg
    44701 ttttcggact gctgttgaat aaacaaatgg cgatagtgac gtagcgccag cgcttcggcc
    44761 tctttcccca gatgttgcgt gacctcgata gtgtccagcg gcgcatgttc cgcctctttg
    44821 gtcacctgcg gcagtgaaaa gacactagcg ataagtagcg aatgctgctg tagattatcc
    44881 gacagcgccg ccaggtgttg ttctatctgg cgaaaagtgc cattcaggcg ttcaacgaga
    44941 tcgtagcggg acatggtatc actcacttta gttacaacat actatctgta tagcacaatt
    45001 cccgcggctc aaccagcgtg caaaatacgt caggccgcgg tcatgtcggg catcgcgtgc
    45061 cagaccggcc agcgaaagct aaattttgcg ccgcccagtt cgctatcgtc acagacgacg
    45121 ctaccgccca tcgccagagc gatagagtgt acgatggcga gtccaagccc gcagccgcct
    45181 gtcgcccggt ctctactggg gtcgagtctg acaaaaggtt caaatacgcg ctctcgcgca
    45241 tccgcttcaa tgccggggcc atcatcttcg actatcagcg ttgcctgact gccgtcaagt
    45301 aacagactga cctgaacggt ggtacggctg tagcgcaacg cattattcag caggttatcc
    45361 agcactcgcg acattaaccg catatcaagc gcgccataat cgccgattac acatgtgaga
    45421 agatttacgg cgcgttccgg gttcacgctc tgcacatcct gcaaatgcgc gaacaaccag
    45481 gcggggaggt cgggtttggt caacatcagt tcattttgtg gtcggtcaag gcgcgcatag
    45541 gtgagcagtt cttcaatcag cgcttccagt tgaccaatat cgcgattgag cgcctgtgat
    45601 tccggcggag tcagattttc actcatttca agccgatagc gtaaacgtac cagcggcgtg
    45661 cgaagctcat gggcgatacc gtcaatcagc tgttttttac tggcgatcag agcattaatg
    45721 ttatccgcca tctggttgaa cgcgacgccc agacgttcga aactggaacc attatcgaaa
    45781 tgcaggcgtt cagtcaaatg accctcgcca aagcgctgcg cggcggattc gagcctgagc
    45841 atttcttgcc agtgcgggcg catccagata aacacaggaa aggcgagaga aaaggcaatg
    45901 agcgccatta aggcgatatc cagcagtcgc atttgatgca ggaaatagag atagggaacc
    45961 gggccaaccg ccaggacgta atggctgcgc gggatacgct gaataaaggt gtattgatcg
    46021 tcaagcgcga caatatcgcc ttcacgcagt cgctgcgtgg tggcggcatc aagcttatag
    46081 tgatttaacg gttcaacgcg taaatcgaaa gagaggttca ggtccatctc ttttaacgtt
    46141 ttcccccatt cacgcggcgg aatttcccgc agttcgctgc gcatcagata gagcgaactt
    46201 ttcatcagat cgtcgagcga ttgcctgccc gcgcgttcgg cagtgaattt gtacaccagt
    46261 ccgaccaata aggtcatgac cagaaaacag acgaacagca aaaggtaaaa ctgcacaaac
    46321 agctttttca tcaacgccca ccggatctca atacattagc tctatcgcgc gctgacggaa
    46381 aagatttccc gtcagcgccg ctggtgggtt ataaaagcag gctttgcgtc aactgacaac
    46441 ctcattgtcc ggcgttaagg tccggacttt cgtgaacaat gcgtccatcg acaagcgtca
    46501 aaacagcgcg aatggtatca attctgtctt ccggcatcgt cataaagggc tgattgagca
    46561 ccgccagatc ggcctgtttt ccgacgctaa gctggccccg gtgttgttcg gcaaaggcga
    46621 gccaggcggc atgacgtgta tataacgcta gcgcttccag acgcgtgagc cgctcgctgg
    46681 cgggtttacg cacggaaccg cctgacgcta taccggtgat atgatattcg atagcgtgcc
    46741 agacaccggc aatgccaata cgcgtcgaat cggtgccgcc agctacgaca agccctttat
    46801 ccagcgccag tcgaaccggc ggcgaattgt ccgtcgcacc gggtgggttg gcgtcacgga
    46861 tggcaagccc ctcaaagtaa ggccccattt gcacagtgta tgccagaccc agcttacgca
    46921 ttcgctcaag tgtctgtggc gaaccggtat tcagatgcgc aatagaccag cggagagggc
    46981 gcagatcgta ctgctgcgct acctgctcaa aaatcgtcaa tatcgcgtcg gcgctgtcat
    47041 cggtataggc gtggatctca agcggtattc cccgttttgc cgcaaacgtc gcgacctggc
    47101 gaagcgcggt tttgtcctgc tctgaggaag aaaaccctgg ggccatccgc acgccgtcat
    47161 tcattcctgc caccaggctt tcccccaggc caagaaaagc cagttgcccg tcgtcggcac
    47221 gcgccgggcg aaaggccatc aggttgctga accactgcgc ttcatgacct ttcgcttccg
    47281 gctgtaccgg aatgcgatac cccacgcgca gcggtaaatc cccctggttt cgcattgcaa
    47341 ataaaggctc ataagcggcg gcaggcccgg cagaggggtc aatgatgccg gtcacgccgc
    47401 gagcgttcat atcagcgaaa aattgtcgca gaccgccctc gcgatcggcg ttactactta
    47461 tgctggcaaa aagctggtta aacgcggcga tgtcaccaaa taatttcccc gtggcgctac
    47521 cttttgcgtc gcgctctacg cggattcccg ctaaatcagg aggaggggtg tcgttaaggc
    47581 caagtacgtc tataccgcgc tgattcacta acgcatagtc gtaaagatac tgaatataag
    47641 ccggatgatc gggaagggcg tggctcagtt cggctaccgt cgacgcccgg ttttctgcaa
    47701 attgcgccgg tatccatgat cccactacgg ctacccattg atcgtgggga cgacggttag
    47761 cgtcggcgcg taatttatcc agcgcgtctt taagcgaagg gctgtcgtac cagtaggttt
    47821 cgaatgtcca ggtttgtccg ccgcgaatgg cgtgaatatg ggtatcggtc aggccgggta
    47881 tcacggtttt accctgtaaa tcgatggtac gggtatggtc gccgcgccat tcatttgtcg
    47941 ccgtatcatc gccaatcgcc acaatccgcg agccggaaat cgccagcgcg ctggcctgcg
    48001 gctgggcatc attcagagtg atgatattac cgttatgcaa aataatatcc gctgccgggc
    48061 gggcggcggt ggctgcgcct gtggccgtga gcagaaagag aagcgcggtt ctggaaagca
    48121 gaggcgggac gagactgatc attagcatgt tccttttgtc gggagataag caaaccatag
    48181 agagcgaaca agaattgttc aatctgtgcc cagggaacag tgcgttctgt ttttagaacg
    48241 gtggtgatag aaatagaaaa agaaaagccc gccgaaacgg cgggcttgag aagaattaat
    48301 gaataattag aactggtaaa ccatacccag cgcgacgata tcatcagtgc tgataccggc
    48361 atctttatag aacgggtcgt cgtcatccag caggttgatt ttataatcaa cataggtgga
    48421 gaagtttttg ttgaaatagt aggtagcacc tacatcagca tatttaacca ggtctttatc
    48481 atcgccatta acgttgttat aggtcagatc tttaccttta gacatcagga aagaaaccgc
    48541 cgggcgcaga ccgaaatcaa attgatattg ggctgtaact tcgaagtttt gcgttttgtt
    48601 tgctacgccg ccatcataac ccttgtccgt tttaccataa ggcgtcatat tacgggtttc
    48661 agaatacata gtcgctaaat agatgttgtt ggcatcatat ttcaagccag ctgtccatgc
    48721 atccgctttg tcgccgccag caatcgtgcc gccagcattg acttgctcat tagtacgatc
    48781 ggaagtggta tacgcagcgc ctgcgctgaa gcccatgcca atatcatagg tagtagaaat
    48841 accgaagcca tcaccgttat cgtaacgaat atcgtcgcca ttattacggt tattggtacc
    48901 gatatttaca tcgtcagcgc tttggctttc atttttaccc tgatattgca acgcgaagtt
    48961 cagaccgtct accagaccga agaaatcagt gttacggtag gtggccacgc cgttagcacg
    49021 accggtcatg tagttgtcag cgtaagtata ggagtcgccg ccgaactcag gcagcatatc
    49081 ggtccagcct tccacgtcgt acaggacgcc gtagttacga ccatagtcga atgagccgta
    49141 gtcgccgaat ttcagaccgg cgaatgccag acgagtccag gagttcgcgc cttcgccttc
    49201 ggtagtgtta gcctgaacgt tatattccca ctggccgtaa ccggtcagtt ggtcgttaat
    49261 ctgcgtttcg cctttaaagc cgacacgcat ataggtctga tcgccatctt tagaagagtc
    49321 atcagagaaa tagtgcaggc cgtctacttt cccgtaaagg tccagtttgt tgccgtcttt
    49381 gttataaatt tcagcggcgt gtgctgcgcc agcagccagc agagc
//
LOCUS       DAJVKX010000020        49212 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000020 DAJVKX010000000
VERSION     DAJVKX010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 49212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49212
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.020"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(32..763)
                     /gene="rlmB"
                     /locus_tag="OPY25_001100"
     CDS             complement(32..763)
                     /gene="rlmB"
                     /locus_tag="OPY25_001100"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCS0926761.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIALHDRPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMPGRMALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRT"
     gene            complement(854..3292)
                     /gene="rnr"
                     /locus_tag="OPY25_001101"
     CDS             complement(854..3292)
                     /gene="rnr"
                     /locus_tag="OPY25_001101"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCS0926762.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASREELAVEL
                     NIEGEEQLEALRRRLRAMERDGQLVFTRRQCYALPERLDLLKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTDA
                     GVGFVVPDDSRLSFDILIPPEDVMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDMALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKVGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVVPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTISAKGRLTGYKFYEAVMSSHARLTYTKVWHMLQG
                     DQDLREQYAPLVKHIEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMIMANISAARFVEKAKEPALFRIHDKPTTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESIADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLSLHRAIKYLLAKEQGNKGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVSDWLKCDFMLDQVGNVFKGVIASVTGFGFFVRLDELFIDGLVHVSSLDNDYY
                     RFDQVGQRLIGESGGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGESKNAGKRRQVGKKVNFEPDSAFRGEKKAKPKAAKKDARKAKKPSAKTQKIAA
                     ATKAKRAAKKKAAE"
     gene            complement(3330..3755)
                     /gene="nsrR"
                     /locus_tag="OPY25_001102"
     CDS             complement(3330..3755)
                     /gene="nsrR"
                     /locus_tag="OPY25_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HCS0926763.1"
                     /translation="MQLTSFTDYGLRALIYMASLPDGRMTSISEVTEVYDVSRNHMVK
                     IINQLSRAGFVTAVRGKNGGIRLGKPANTICIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLKELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(3975..5273)
                     /gene="purA"
                     /locus_tag="OPY25_001103"
     CDS             complement(3975..5273)
                     /gene="purA"
                     /locus_tag="OPY25_001103"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCS0926764.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPSALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEYGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(5376..5573)
                     /locus_tag="OPY25_001104"
     CDS             complement(5376..5573)
                     /locus_tag="OPY25_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 family protein"
                     /protein_id="HCS0926765.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPGAWKKMVSALAQLPENVLRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(5652..6656)
                     /gene="hflC"
                     /locus_tag="OPY25_001105"
     CDS             complement(5652..6656)
                     /gene="hflC"
                     /locus_tag="OPY25_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HCS0926766.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDENK
                     PLVYAPGLHFKIPFIESVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTDDEVATPAADDAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRAAADYEVTKTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSQDPDFYAFIRSLRAYEKSFEGNQDVMVLSPDSDFFRYMKTPSSTTR
                     "
     gene            complement(6659..7918)
                     /gene="hflK"
                     /locus_tag="OPY25_001106"
     CDS             complement(6659..7918)
                     /gene="hflK"
                     /locus_tag="OPY25_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HCS0926767.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGSNSGGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGFGGGKGTGSGGGSSSQGPRPQLGGRIVAIAAAAVVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDDVTPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTDPQKYLFSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIKPYNMGITLLDVNFQAARPPEEMKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKTQTILEAQGEVARFAKILPEYKAAPQITRERLYIETMEKV
                     LSHTRKVLVNDKSGNLMVLPLDQMLKGGNAPAAKSDNSASNLLRLPPSTKSNASGASN
                     TSSSNQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(8133..9413)
                     /gene="hflX"
                     /locus_tag="OPY25_001107"
     CDS             complement(8133..9413)
                     /gene="hflX"
                     /locus_tag="OPY25_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCS0926768.1"
                     /translation="MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFESLVSSAGVEAMQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGAAVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLEKVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNQIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPYDLVAAFKATLQETRQ
                     ATLLLHVVDAADVRVQENIEAVNTVLEEIDAHEIPTLMVMNKIDMLDDFEPRIDRDEE
                     NKPIRVWLSAQSGVGIPQLFQALTERLSGEVAQHTLRLLPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIEYVI"
     gene            complement(9485..9793)
                     /gene="hfq"
                     /locus_tag="OPY25_001108"
     CDS             complement(9485..9793)
                     /gene="hfq"
                     /locus_tag="OPY25_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HCS0926769.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
                     "
     gene            complement(9876..10826)
                     /gene="miaA"
                     /locus_tag="OPY25_001109"
     CDS             complement(9876..10826)
                     /gene="miaA"
                     /locus_tag="OPY25_001109"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCS0926770.1"
                     /translation="MNDVSKVSLPKAIFLMGPTASGKTALAIELRKVLPVELISVDSA
                     LIYRGMDIGTAKPNADELKAAPHRLLDIRDPSQAYSAADFRRDALAQMAEITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRSRIEQQAAELGWEALHQQLQEIDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIELRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYIEGEISYDEMVYRGVCSTR
                     QLAKRQMTWLRGWEGVRWLDSENPDRARKEVLQVVGAIAD"
     gene            complement(10819..12675)
                     /gene="mutL"
                     /locus_tag="OPY25_001110"
     CDS             complement(10819..12675)
                     /gene="mutL"
                     /locus_tag="OPY25_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCS0926771.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRVDI
                     DIERGGAKLIRIRDNGCGIKKEELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQAEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     MRTEKTEFNHIDEIIRRIALARFDVTLNLSHNGKLVRQYRAVAKDGQKERRLSAICGT
                     PFLEQALAIEWQHGDLTLRGWVADPNHTTTALTEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQT
                     ETTLPLEEIAPAPRHVPENRIAAGRNHFAVPAEPTAAREPATPRYSDGASGGNGGRQS
                     AGGWPHAQPGYQKQQGEVYRTLLQTPTTSPAPEPVAPALDGHSQSFGRVLTIVGGDCA
                     LLEHAGTIQLLSLPVAERWLRQAQLTPGQSPVCAQPLLIPLRLKVSADEKAALQKAQS
                     LLGELGIEFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAQQTTFATVNIAQWIAR
                     NVQSEHPQWSMAQAISLLADVERLCPQLVKAPPGGLLQPVDLHSAMNALKHE"
     gene            complement(12685..14004)
                     /gene="amiB"
                     /locus_tag="OPY25_001111"
     CDS             complement(12685..14004)
                     /gene="amiB"
                     /locus_tag="OPY25_001111"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HCS0926772.1"
                     /translation="MIYRIKNAVIAALILLCAQAGAASLSDIQVSNGEQQARITLSFI
                     GEPEYAYSQDGKRTVALDIRQTGVIQGLPLQFSGNNLVKTIRAGTPKDAQSLRLLVDL
                     TENGKTEAVKRQNGGNYTVIFTINADVPPPPPPVVAKRVESAPRPTEPARNPFKSSDD
                     RLTGVTSSNTVTRPAARASAGAGDKVVIAIDAGHGGQDPGAIGPGGTREKNVTIAIAR
                     KLRTLLNNDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRDATGAS
                     VWVLSNRRANSEMANWLEQHEKQSELLGGAGDVLTNSQSDPYLSQAVLDLQFGHSQRV
                     GYDVATNVLSQLDGVGSLHKRRPEHASLGVLRSPDIPSILVETGFISNHGEERLLASD
                     RYQQQIADAIYRGLRKYFAAHPIQSAPQGSPGQTASTNQPGAITAAN"
     gene            complement(14021..14482)
                     /gene="tsaE"
                     /locus_tag="OPY25_001112"
     CDS             complement(14021..14482)
                     /gene="tsaE"
                     /locus_tag="OPY25_001112"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCS0926773.1"
                     /translation="MMNRVIPLPDEQATLDLGQRVANACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHNGNVKSPTYTLVEPYALDNMMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGKGVLPDPDVEIHIDYQAQGREARVSAVSSSGHSLLARLAD"
     gene            complement(14454..16001)
                     /gene="nnr"
                     /locus_tag="OPY25_001113"
     CDS             complement(14454..16001)
                     /gene="nnr"
                     /locus_tag="OPY25_001113"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HCS0926774.1"
                     /translation="MMDHNMKKNPVSIPHSIWPADDIKRLERDAADAFGLTLYELMLR
                     AGDAAFRVARDSYPDARHWLVLCGHGNNGGDGYVVARLAQAAGISVTLLAQESDKPLP
                     EEAAQARDAWLNAGGIIHAADIIWPEATDLIIDALLGTGIAQEPRDPVAGLIEQANAH
                     PAPVVAVDIPSGLLAQTGTTPGAVISAAHTVTFIALKPGLLTGKARDVTGILHYDALG
                     LEGWLASQTPPLRRFDATQLGQWLTPRRPTSYKGDHGRLAIIGGDQGTAGAIRMAGEA
                     ALRTGAGLVRVLTRGENIASLLTARPELMVHELTPQSLEESLTWADVVVIGPGLGQQE
                     WGKKALQKVENVRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLLSAQRLVKRYGGVVVLKGAGTIIAAEHHPLAIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKFTPYDAACVGCVAHGAAADLLAARYGARGMLATDLFTTLRRIVNPDVIDVNHD
                     ESSNSAT"
     gene            16000..17139
                     /gene="queG"
                     /locus_tag="OPY25_001114"
     CDS             16000..17139
                     /gene="queG"
                     /locus_tag="OPY25_001114"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCS0926775.1"
                     /translation="MSKPLDLNQLAQNIKQWGLELGFQQVGITDTDLRASEPALQAWL
                     DKQYHGEMAWMARHGMMRARPHELLPGTLRVISVRMNYLPANAAFASTLKDPTLGYVS
                     RYALGRDYHKLLRSRLKKLGEQIQQYCGSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLIDLPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPEAFRPLIGNRIYGCDDCQLICPWNRYSQLTDEADFSPRKALHNP
                     DLLELFSWSEAQFLKVTEGSAIRRIGHLRWLRNVAVALGNAPWSNAVITALESRKGEH
                     PLLDENIEWAIAQQIEKRNACIIEVQLPKKQRLVRVIEKGLVRDA"
     gene            complement(17409..17484)
                     /locus_tag="OPY25_001115"
     tRNA            complement(17409..17484)
                     /locus_tag="OPY25_001115"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17449..17451),aa:Gly,seq:gcc)
     gene            complement(17641..17716)
                     /locus_tag="OPY25_001116"
     tRNA            complement(17641..17716)
                     /locus_tag="OPY25_001116"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17681..17683),aa:Gly,seq:gcc)
     gene            18012..18731
                     /locus_tag="OPY25_001117"
     CDS             18012..18731
                     /locus_tag="OPY25_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HCS0926776.1"
                     /translation="MLLASLSVHAASVSARTLHFGTSATYAPYEFVDADNKIVGFDID
                     VANAVCKEMQAECSFTNQSFDSLIPGLRFKKFDAVIAGMDMTPKREQQVSFSQPYYEG
                     LSAVVVTRKGAYHTFADLKGKKVGLENGTTHQRYLQDKQQAITPVAYDSYLNAFTDLK
                     NNRLEGVFGDVAAIGKWLKNNPDYAIMDERASDPDYYGKGLGIAVRKGNDALLQEINA
                     ALDKVKASPEYAQMQEKWFTQ"
     gene            complement(18793..19338)
                     /gene="orn"
                     /locus_tag="OPY25_001118"
     CDS             complement(18793..19338)
                     /gene="orn"
                     /locus_tag="OPY25_001118"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HCS0926777.1"
                     /translation="MSADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGP
                     TIAVHQSDAQLALMDDWNVRTHTGSGLVDRVKASTMGERDAELATIEFLKTWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
     gene            19445..20497
                     /gene="rsgA"
                     /locus_tag="OPY25_001119"
     CDS             19445..20497
                     /gene="rsgA"
                     /locus_tag="OPY25_001119"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HCS0926778.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSAEKADYDDNLFGEPAEGIV
                     ISRFGMHADVESADGEVHRCNIRRTIRSLVTGDRVVWRPGKAAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVGCETLQVEPLIVLN
                     KIDLLDDEGMDFVNEQMNIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQNEILTNDVSNVSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGHCKYRDCKHDADPGCAIREAVENGAIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            20589..21557
                     /gene="psd"
                     /locus_tag="OPY25_001120"
     CDS             20589..21557
                     /gene="psd"
                     /locus_tag="OPY25_001120"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463212.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HCS0926779.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMTEAQKPDTASYRTFNDFFVRPLRDDVRPLNTDPNILVMPADGVISQLGRIEED
                     KILQAKGHNYSLEALLAGNYLMADKFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNYLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPEGEHEGSVALLKGQEMGRFKLGSTVINLFAPGKVNLIASLASLSV
                     TKIGQPLATSTETFVAPEVEPAPLPAEEIKAEHDASPLVDNKKDDT"
     gene            21576..24902
                     /gene="mscM"
                     /locus_tag="OPY25_001121"
     CDS             21576..24902
                     /gene="mscM"
                     /locus_tag="OPY25_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HCS0926780.1"
                     /translation="MRLIIAFLMAWCLSTGAFAATAPDAKQITQELEQAKAAKPAQPE
                     AVEALQTALNALEERKGSLERAKQYQHVIDNFPKLSATLRAQLNNLRDEPRSVPPEMS
                     TEALNQEILQVSSQLLDKTREAQQEQERVREIADSLSQLPQQQNDARRQLNEIERRLG
                     AAGGSAALSQAQSLSMQAESAKLKALVDELELAQLSANNRQELARLRSELAEKQSQQL
                     DAYLQALRNQLNSLRQREAERALESTELLAENSAGLPEGIVEQFKVNRGLSQALNQQA
                     QRMDLVASQQRQATSQTLQVRQALNTLREQSQWLGVSNMLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVHRMRYEELLNKQPQLRQIRQANGQPLTAEQNQILDAQLRTQRELLNS
                     LLQGGDTLILELTKLKVSNSQLEDALKEVNEATHRYLFWTADVSPLSLSWPVDLVQDL
                     RRLISLDTFNQLGKASIMMLTSKETLLPLFGALALVGFSLYSRQHFNRFLERSASRVG
                     KVTQDHFSLTLRTVFWSILVASPLPVLWATLGYGLQEAWPYPLAVAIGDGVTATVPLL
                     WVVMICAAFARPNGLFVAHFGWPRNRVAKAMRYYLMSIGLIVPLIMAVIMFDNLNDRE
                     FSGSLGRLCFILICGALALVTLSLKKAGIPLYLDKEGNGDNMVNSLLWNMLMGAPLIA
                     ILAAAVGYLATAQALLARLETSVAIWFLLLVIYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEPAHSSSLEGAVDIDESEIDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LALLQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTQILLTAAQRCSLVLDNPPPEIFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFREHGIDMPFPPFQMRLESLGG
                     KQTGRTLTSAGKTSRPAGSL"
     gene            complement(25039..25359)
                     /locus_tag="OPY25_001122"
     CDS             complement(25039..25359)
                     /locus_tag="OPY25_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001682126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926781.1"
                     /translation="MNDSSRDPIITEDEIRALNFTPEDILEIEKVILSSVHVARRKVA
                     MVVGMTIGTLRDRDEDKWKHVSDIYCAYVVRCLVFRGELVGYGDLFRMRYSEINLPVA
                     DLDA"
     gene            complement(25424..26926)
                     /gene="yjeM"
                     /locus_tag="OPY25_001123"
     CDS             complement(25424..26926)
                     /gene="yjeM"
                     /locus_tag="OPY25_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HCS0926782.1"
                     /translation="MTHTIKKMSLIGLILMIFTSVFGFANSPSAFYLMGYSAIPWYIF
                     SALLFFIPFALMMAEMGSAYRKEEGGIYSWMNNSVGPRYAFIGTFMWFSSYVIWMVST
                     AAKIWVPFSTFVFGADMTQHWRIAGLEPTQVVGLLAVGWMILVTCVAARGINKIARIT
                     AVGGIAVMCLNLVLLLVSVAILLLNGGHFAQEINFTSSPNPGYHSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTEKPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQILSNSA
                     VNLGNITYILMSSLGTTLGNALNLSPEAAMTVGVWFARITGLSMFLAYTGAFFTLSYS
                     PLKAIIQGTPKALWPAPMTTLNANGMPATAMWLQCVLVSLFILLVSFGGDTASAFYNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLERPFVLFKTKASTLVATGVVVLVVTFANV
                     FTIIQPVIEAGDWDSALWMIGGPIFFSLLAMAIYQNYSSRMSADPEWAAE"
     gene            complement(27152..28129)
                     /gene="epmA"
                     /locus_tag="OPY25_001124"
     CDS             complement(27152..28129)
                     /gene="epmA"
                     /locus_tag="OPY25_001124"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HCS0926783.1"
                     /translation="MSETATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLFPFETRFVGPGHSQGINLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNE
                     EMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFLRHLEID
                     PLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     QPIDQNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA"
     gene            28452..30242
                     /gene="frdA"
                     /locus_tag="OPY25_001125"
     CDS             28452..30242
                     /gene="frdA"
                     /locus_tag="OPY25_001125"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HCS0926784.1"
                     /translation="MQTFQADLAIIGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFDYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLEQWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDNHARGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVHLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCESRVKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQAMERAATAGAANSAALDAQVADIEQRLKNLVNQEGNENWS
                     KIRDEMGLSMEEGCGIYRTPELMQKTVDKLAELQERFKRVRISDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSALARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEAEAADKKEKANG"
     gene            30235..30969
                     /gene="frdB"
                     /locus_tag="OPY25_001126"
     CDS             30235..30969
                     /gene="frdB"
                     /locus_tag="OPY25_001126"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HCS0926785.1"
                     /translation="MAEMKNLKVEVVRYNPETDTAPHSAFYEVPYDETTSLLDALGYI
                     KDNLSPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTNGMKVEALANFPIERD
                     LVIDMTHFIESLEAIKPYIIGNSRTPDQGPNVQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSPNGVWTCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            30980..31375
                     /gene="frdC"
                     /locus_tag="OPY25_001127"
     CDS             30980..31375
                     /gene="frdC"
                     /locus_tag="OPY25_001127"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HCS0926786.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKGLWVVTAVVTVVILYVALFW"
     gene            31386..31745
                     /gene="frdD"
                     /locus_tag="OPY25_001128"
     CDS             31386..31745
                     /gene="frdD"
                     /locus_tag="OPY25_001128"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HCS0926787.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVGIMLPLGL
                     FPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTAIGVITL"
     gene            31857..32390
                     /locus_tag="OPY25_001129"
     CDS             31857..32390
                     /locus_tag="OPY25_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HCS0926788.1"
                     /translation="MRLLPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWY
                     EIARLDHRFERGLEQVTATYSLRDDGGINVINKGYNPAREMWQKTEGKAYFTGSPNRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPNRDYLWILSRTPTLSEEIKQQMLAVAT
                     REGFDVNKLIWVKQSGS"
     gene            complement(32407..32724)
                     /gene="sugE"
                     /locus_tag="OPY25_001130"
     CDS             complement(32407..32724)
                     /gene="sugE"
                     /locus_tag="OPY25_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HCS0926789.1"
                     /translation="MSWIILLIAGLLEVVWAVGLKYTHGFSRLTPSIITITAMVISMA
                     LLSWAMKTLLVGTAYAIWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKL
                     SAH"
     gene            32980..33567
                     /locus_tag="OPY25_001131"
     CDS             32980..33567
                     /locus_tag="OPY25_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0926790.1"
                     /translation="MLKILVIDRCHFTRTGMEAWLNHTDVLSSSLLVSGMNNLILAKE
                     HILQWKPHLVIADLYGFLNDALPEQPINAFFAACRMTPLVLLQSGNMPYRSQYASHAV
                     LSKHTPLHELAQRIKGALYTHPLQEAPESATPLLSPQEEKVLAMWTEGTSNKEIAYAL
                     GIHGKTVYTYKRNIRMKLHMDNRYSPFLMLPEKID"
     gene            complement(33598..33744)
                     /gene="ecnB"
                     /locus_tag="OPY25_001132"
     CDS             complement(33598..33744)
                     /gene="ecnB"
                     /locus_tag="OPY25_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HCS0926791.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGSAISGAAT
                     RAQQ"
     gene            complement(33852..33986)
                     /locus_tag="OPY25_001133"
     CDS             complement(33852..33986)
                     /locus_tag="OPY25_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463199.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entericidin A/B family lipoprotein"
                     /protein_id="HCS0926792.1"
                     /translation="MMKRFIGLVALVLLTGTLLTACNTARGFGEDIQHLGHAISRAAS
                     "
     gene            complement(34047..34613)
                     /gene="efp"
                     /locus_tag="OPY25_001134"
     CDS             complement(34047..34613)
                     /gene="efp"
                     /locus_tag="OPY25_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCS0926793.1"
                     /translation="MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            34654..35682
                     /gene="epmB"
                     /locus_tag="OPY25_001135"
     CDS             34654..35682
                     /gene="epmB"
                     /locus_tag="OPY25_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HCS0926794.1"
                     /translation="MAHIVTLNTPLREDWLAQLADVVTNPDELLHLLQIEADENLRAR
                     QDARRLFALRVPRAFIARMEKGNPDDPLLRQVLTSRDEFIVAPGFSTDPLEEQHSVVP
                     GLLHKYQNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWTVALEYIAAHPELDEI
                     IFSGGDPLMAKDHELDWLLTQLEAIKHVKRLRIHSRLPIVIPARITDELVARFDQSCL
                     QILLVNHINHANEVDEAFCLAMKKLRHVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVTDDEARQIMRELLTLVSGYMVPRLAREIGGEPSKTP
                     LDLQLRQC"
     gene            35964..36821
                     /locus_tag="OPY25_001136"
     CDS             35964..36821
                     /locus_tag="OPY25_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HCS0926795.1"
                     /translation="MALTIKGLNTGVIRHNDKFIALALKVKSLRNKETLLFFPVLALR
                     DLLIGLEHRLYLQYSLPEQEQEKRQKAKSSHVLKMHENIPAILREELENADVNQRVES
                     LALSDNTEKVLTFTLKLHNGSHLDLQVGEWQVEVLVMAIIHAINNAEMRELALRISSM
                     LDFLPLYDADCLDNGNIEFDTYNQPDWKHNLYNHYLALVYRYTDEAGQSHDCGTIIKT
                     RSQSGSKEAEAISRRLLNFSPRLKKLEGKPCKVFVRTLGTGKAARLTQDQCMRALHNL
                     RMASSQEKR"
     gene            complement(36869..37222)
                     /locus_tag="OPY25_001137"
     CDS             complement(36869..37222)
                     /locus_tag="OPY25_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HCS0926796.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELTAAGQNVRFVEDKPGAECQ
                     LIGTATGKQSNWFSGQHGEEGGSMRGAANDLRNQAAAMGGNVLYGVSSPSQGMLSSFV
                     PTASEMNGQVYKCPN"
     gene            complement(37466..39112)
                     /gene="groL"
                     /locus_tag="OPY25_001138"
     CDS             complement(37466..39112)
                     /gene="groL"
                     /locus_tag="OPY25_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCS0926797.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITE
                     GLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM"
     gene            complement(39156..39449)
                     /locus_tag="OPY25_001139"
     CDS             complement(39156..39449)
                     /locus_tag="OPY25_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCS0926798.1"
                     /translation="MSIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEIIAVG
                     KGRILDNGTVQPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            39725..40966
                     /locus_tag="OPY25_001140"
     CDS             39725..40966
                     /locus_tag="OPY25_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCS0926799.1"
                     /translation="MNELKKELGLVQGVILLTTSLLGTGVFALPELAALAAGDISLWA
                     WPLLIILIFPIAIVFAVLGRHFPHAGGVAHFVGMAFGPRLQRVISWLFLSVIPVSFPA
                     ALHIAVGFGQALFGWQSEQLLFGELGTLGLLWFMGSRGASSSANLQAIIAGLIIALIA
                     AILWKGAIKPADITFPAANEIIFSRLCTALAIMFWGFVGIEAFTHLSSEFKNPERDFP
                     RALIIGLMLAGAIYWTCTAVVLHFGVYSDKIAATASLPLIIVHLFGIQALWIACIIGY
                     LTCFASLNMYAQSFARLIWTQMQYQPDHYLAQLSPGRLPLHALNVILACCCVSSLVVY
                     ALKINLNALIVYANGIFIMLYLLCMLAGCRLLKGRCYALAVTGCLLCLLLLVMLGWKS
                     LYAIIMLAALWLFLPKRKRMA"
     gene            complement(41025..41501)
                     /gene="fxsA"
                     /locus_tag="OPY25_001141"
     CDS             complement(41025..41501)
                     /gene="fxsA"
                     /locus_tag="OPY25_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HCS0926800.1"
                     /translation="MRWIPFLAVFLYVYIEISIFIQVAHVLGVLMTLILVIFTSVIGM
                     SLVRNQGFKNFLLMQQKMAAGESPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTLKLLPHLRFSRMPGGGFSAGTGGGETFDGEYQRKDDDRDRIEHKDDRRD"
     gene            41842..43278
                     /gene="aspA"
                     /locus_tag="OPY25_001142"
     CDS             41842..43278
                     /gene="aspA"
                     /locus_tag="OPY25_001142"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HCS0926801.1"
                     /translation="MSNNIRIEEDLLGTREVPAEAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAALANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRVAVYASI
                     VKLIDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKSI
                     ERTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFACVPAEDLIEATSDCGA
                     YVMVHSALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESIHILSNACYNLLEKCVN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            43393..44694
                     /gene="dcuA"
                     /locus_tag="OPY25_001143"
     CDS             43393..44694
                     /gene="dcuA"
                     /locus_tag="OPY25_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HCS0926802.1"
                     /translation="MIVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGT
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVNQTEKLLRKNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYIHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLIELRGEKQIE
                     IKPMAKNSVWLFLLGVICVVVYAIVNSPSLGLVEKPLMNTTNAILIIMLSVATLTTIL
                     CKVETDAILNSSTFKAGMSACICILGVAWLGDTFVSANIDWIKDTAGSVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVVLAICSGFLLGSFML"
     gene            44815..45162
                     /gene="cutA"
                     /locus_tag="OPY25_001144"
     CDS             44815..45162
                     /gene="cutA"
                     /locus_tag="OPY25_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HCS0926803.1"
                     /translation="MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACAT
                     LLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHG
                     DTDYLSWLNASLR"
     gene            45138..46841
                     /locus_tag="OPY25_001145"
     CDS             45138..46841
                     /locus_tag="OPY25_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HCS0926804.1"
                     /translation="MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQN
                     QHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLPAGVWHEDEFYGKSEIYRKRLNV
                     PVTVNQAAAGATLTITYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTGETS
                     KPAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQ
                     GMALTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQT
                     RLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYL
                     YALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRL
                     WSLLGVAFFGWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHL
                     NFTAISTVDELNQALAQAKGKPVMLDFYADWCVACKEFEKYTFSDPRVQQVLGDTVLL
                     QANVTANNAQDVALLKHLQVLGLPTILFFDAQGQEQPQARVTGFMDAATFSAHLHDRQ
                     P"
     gene            46878..47453
                     /locus_tag="OPY25_001146"
     CDS             46878..47453
                     /locus_tag="OPY25_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0926805.1"
                     /translation="MQREDILGEALKLLETQGIADTTLEMVAERVNRPLDTLQRFWPD
                     KEAILYDALRYLSQQVDIWRRQLLLDETFSAEQKLLARYSALSECVSNNRYPGCLFIA
                     ACTFYPDPTHPIHQLANQQKRAAHDFTHGLLTTLEIDDPAMVARQMELVLEGCLSRML
                     VNRSQADVDTAQRLAEDILRFAQCRQGGALT"
     gene            47569..47644
                     /locus_tag="OPY25_001147"
     tRNA            47569..47644
                     /locus_tag="OPY25_001147"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47602..47604,aa:Phe,seq:gaa)
     gene            47804..49063
                     /locus_tag="OPY25_001148"
     CDS             47804..49063
                     /locus_tag="OPY25_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HCS0926806.1"
                     /translation="MLTDSKIRAAKPLAKSYKLTDAQGLYLTVSTSGSKLWYFRYRFE
                     GKENRLAFGPYPQVTLAEAREKRDAARKLLVSGVCPSLPRKAEKAAVDGTRTFQYIAT
                     AWHSSCLKLWSEDHADKILTCLKRYVFPDIGAMDIAEVETRHLAQLVKSIDDKGVHDV
                     AGRVRQHLTKIMRHAVQQGTIKYNPAYDLDGVVTPVVTQHHPALPLKRLPELLDKING
                     YKGRELTRLALELNLHVFLRSSELRLARWDEFNLKARIWTVPAKREAVKNVRFSERGA
                     KMKDEHLVPLSAQAVALLEQIKEITGESVFVFAGAHSMNKPMSENTINKALRVIGYDT
                     KTEVCGHGFRTMACSALNESALWSKDAIERQMSHKERNGVRAAYVHKAEHLEARMEMM
                     QWWSDYLDMSREGYVAPYIYARRHKAA"
BASE COUNT        11454 a        13526 c        12567 g        11665 t
ORIGIN      
        1 gatggttttt tcttaaaaaa tactattagc gtcaggtacg ctggcgaacg gcttcaaaca
       61 gacaaatccc ggtcgccaca gagacattca gcgatgacac gctaccggcc ataggaatgc
      121 tgatcagctc atcgcagtgc tcacgggtca gacgacgcat accttcacct tctgcgccca
      181 tgaccagcgc catgcggcca ggcattttgc tctgatacag cgtatggtca gcctcgcccg
      241 ccgttccgac aatccagata ttctcttcct gcaacatgcg catcgtgcgc gccaggttgg
      301 tgacgcggat caacggcacg ctttccgctg cgccgcaggc gactttcttc gccgtcgcgt
      361 taagttgcgc ggagcggtct ttcggcacga ttaccgcatg tacgcctgca gcatcggcgc
      421 tgcgcagaca ggcgccaaga ttatgcggat cggtgacgcc atcgaggatc aacaaaaagg
      481 ggcgatcgtg taatgcgatc agatccggta gatcgttttc ctgatactgc cggcctggtt
      541 tcacacgagc gataatgccc tgatgcacgg caccgtcgct tttctcgtcg agatattggc
      601 ggtttgccag ctggataacc acgccctggg actcaagggc gtgaatcagc ggcaacagac
      661 gtttatcttc acggcctttt aaaataaaga cttcctgaaa acgttcaggg gcgcgctcca
      721 gcagggcctg cactgcgtgg atgccgtaaa tcatttcgct cattaatgta ctcgttgttt
      781 acgttttgcc gggggcgcta cgcttgcccg gcctacagat aattgaccct cttctgtttg
      841 aagagggtat tgctcactct gccgcttttt tcttcgccgc acgcttcgct ttggtcgctg
      901 cggctatttt ctgcgtttta gccgatggct tttttgcttt tctcgcgtct ttcttcgctg
      961 ctttcggctt cgcttttttc tcgccgcgga aggcgctatc aggctcgaag ttaacctttt
     1021 tacctacctg acgacgttta ccggcgtttt tactttcacc ttttttcgct ttttcacgcg
     1081 ccgttttgcc gacgttacgc ggtgcgcgct cgctggaaat caagctaaag tcaattttcc
     1141 gttcgtccat attcaccgct tcgacgcgta cctcgacccg gtcgcccagg cgatatgtct
     1201 gcccgccgga ttcgccaatc agacgttgcc ctacctgatc gaagcgatag taatcgttat
     1261 ccagtgagga aacgtgtacc agcccatcga taaacagttc atcaagacgg acaaagaagc
     1321 cgaaaccggt gacgctggca atcacgccct taaagacgtt gcctacctga tccagcataa
     1381 agtcacattt cagccagtcg gagacatcac gcgtcgcttc atcagcgcgg cgttccgcca
     1441 tcgaacagtg ctggccgagc tgcaacatct cttccatcga gtagtgataa ccgcccgttt
     1501 ctgtggtgtt gcccttgttc ccttgctctt tagccagcag gtacttaatg gcgcggtgca
     1561 aagaaagatc cggatagcgg cgaatcggcg aggtaaagtg cgcataagac tgcaacgcca
     1621 ggccaaagtg cccgcggttt tccggatcgt aaatcgcctg cttcattgaa cgcagcagca
     1681 tagtttgcag catttcggcg tccggcctgt cggcaatcga ttcaagcagt tcggcataat
     1741 cgcgcggttc cggtttattt ccgcccggca gctccaaccc cagctccgcc agtacggagc
     1801 ggaatgaggt gatcgcttcg gtggtgggct tatcatgaat acggaataac gccggctctt
     1861 tagctttttc gacaaagcgc gccgccgaga tattcgccat gatcatgcac tcttcgataa
     1921 gcttatgcgc gtcattacgc tgggtctgtt cgatacgctc aatgcgacgc tcggcgttaa
     1981 agataaactt cgcctcttcg ctctcaaacg agatcccccc gcgttcttca cgcgctttat
     2041 ccagcacttt gtagaggttg tgcagctctt caatatgctt caccagcggc gcatattgtt
     2101 cacgcagatc ctgatcgccc tgcagcatat gccagacttt ggtataggtc agacgcgcat
     2161 gggagctcat caccgcttca tagaatttgt agccggtcag ccgacctttc gccgagatgg
     2221 tcatttcaca gaccatacac agcctgtcaa cctgcgggtt tagcgaacac aggccgttgg
     2281 agagcacctc cggcaacatt gggacaacct gtgacgggaa gtaaaccgac gtgccgcgat
     2341 tgcgcgcctc gcgatccaac ggcgttggcg gccgtacata atagctcacg tcagcaatag
     2401 cgacccacaa acgccagccg ccgccgcgtt ttttctcaca gtaaaccgcg tcgtcaaagt
     2461 cacgggcatc ttcgccatca atcgtgacca gcggcaaatc gcgcagatcg acacgaccga
     2521 ctttcgcctc ttccggcacc tcttctttca gcccggcgac ctgctgctct accgcctgcg
     2581 gccagatgta gggtatttca tgggtacgca gcgccatatc aaccgccata ccggtaccca
     2641 tattgtcgcc cagcacttcg acgattttcc ctaccgcttt agtacggcga gttggacgtt
     2701 gggtcagttc aaccacgacc acgaacccca tccgcgcgcc catgacgtct tctggcggga
     2761 taagaatgtc gaagctgaga cggctgtcgt ccggcaccac aaagccgacg cccgcatcgg
     2821 tgaaataacg cccgactatc tgactggttt tcggtaccag tacacggacg atacgcgctt
     2881 cgcggcgacc tttacgatcg gcgcccagcg gctgcgccag cacctgatcg ccatgaatac
     2941 aggttttcat ctgctcgctg gaaagataca gatcgtcttt gcggccttcg acacgtaaga
     3001 aaccgtaacc atcacgatga ccgatcacgg tgcctttcag caggtcgagg cgttccggca
     3061 gcgcatagca ctggcggcgg gtaaagacca gttgtccatc gcgctccatc gcgcgcaggc
     3121 ggcgacgcaa ggcttcaagc tgctcttcgc cttcaatatt cagttctacg gccagttctt
     3181 cgcgactggc cggtttttca cgtttcgtta aatgttcgag gataaattcc cggctcggga
     3241 taggattcgc gtatttttct gcttcgcgtt cctggaaagg atcttgtgac attgaggttc
     3301 ctccattgtc atctctaatg aagtttactt cactccacca gtaataattt ataaagcggt
     3361 tgattctctt caaccaaatc ggcaagcgtg tagttatcca gctccttgag aaaactctgc
     3421 acggccttag aaagcgcctg tttcagacga caggcagggg tgatgtggca aaattcgctg
     3481 ctacagttga ccagtgataa gggttccagc tcacgcacca catcgccaat acaaatagta
     3541 ttagccggtt tacccaggcg gataccgcca ttttttcccc gaacggcggt gacaaagccc
     3601 gcccggctaa gctgattgat aattttgacc atatgattac gggacacgtc gtagacttct
     3661 gtcacctcag aaatgctggt cattcgtcca tctggtaacg acgccatata gattagcgca
     3721 cgtaagccgt aatcggtgaa actcgttaac tgcacatcaa cctcaggaaa agggaaaacg
     3781 ggatataact tatctgtatt gatgataaac cagccacctg tcaggctgct aatttatttc
     3841 ggttcaggaa ggaaaaaagc ggggaacaat gacgcatttg agccgaagga tgatgcaaag
     3901 catcttatcc ggccaacaaa tgcgtactca tcatagaccc ggtaagcgta gcgttaccgg
     3961 gcatcatcca tcaattacgc gtcgaacgga tcgcgcagaa tcatcgtctc agtacgatcg
     4021 gggccggtag aaataatatc aatcggcacg ccggtcagtt cttcgatacg tttgatgtag
     4081 ttcagcgccg cctgcggcag gccgctacga tctttcacgc cgaaggtgga ttcagaccag
     4141 cccggcatgg tttcgtaaat cggctctaca cctttccagt cgtcagctgc cagcggagtg
     4201 gtagtcactt cgcgaccatc cggcatacgg taagccacgc agagtttcac ctctttcagg
     4261 ccatccagca cgtccagttt ggtcaggcag aagccagaca gggagttcag ctgtaccgca
     4321 cgacgaacgg caacggtgtc cagccagccg gtacgacgac gacggccggt agtggcgccg
     4381 tattcgttac cctgcttgca gaggaactcg ccggtttcat caaacagttc ggtcgggaac
     4441 ggacctgcac ctacacgagt ggagtaagct ttgaggatac ccagaacgta atcaacataa
     4501 cgcgggccca ggccggaacc ggtcgccacg ccacccgcag tggtgttaga agaagttacg
     4561 tacggataag taccgtggtc gatatccagc agggtaccct gcgcaccttc aaacatgacg
     4621 aaatcgccac gctgacgcgc ctggtcgagc aggtctgaaa cgtcaacaac catagaagtc
     4681 aggatgtcgg caacagccat cgtatcatcc agaactttct ggtaatcaac cgcttcagct
     4741 ttgtagtagt taaccaactg gaagttgtga tattccatca cttctttcag tttttcagca
     4801 aaggtttctt tgtcgaaaag gtcaccaaca cgcagaccgc gacgtgccac tttatcttca
     4861 taagcaggcc cgattccacg accggtggtg ccgatcgctt tcgcgccacg cgctttctca
     4921 cgcgcgttat ccagcgcaac gtgataatca aggatcagcg gacaggcttc agacagcagc
     4981 agacgctcac gaacggggat gccacggtct tccagttctt tcatctcttt catcagcgcg
     5041 ctcggagaca gcacaacacc gttaccgatg atgctggtta cattctcgcg aagaatacct
     5101 gatggaataa gatggagaac ggttttttca ccgttgatta cgagagtatg gcctgcgttg
     5161 tgaccgccct ggtagcgtac aacatattta gcccgttcag tcagaagatc gacgatcttt
     5221 cctttacctt cgtcacccca ttgggtgccc agtacgacga cgttgttacc catttttcaa
     5281 aatcaccgtt tgcttaaaaa tggattctac catcgctttt tcagatatac agcacttttt
     5341 gcactcaatc tgcggcaaat ccgaccactt tttgctcagc caatcgtttt cctcaacatg
     5401 tagtagacca caactcccgc gaccacaagt ccgccgccaa aacgacgtaa aacattttcc
     5461 ggcagttgcg ccagtgccga aaccattttt ttccatgcgc cgggatacag catcggtccc
     5521 agcccttcga ggactaatac cagagcaagc gccaaccaga ttgttgaatt catttatcgc
     5581 ccttataaaa gaaaaccacc ggcatccttt ggatgcggtg gttttgctgg tctaaaaccg
     5641 ctgacgctat tttagcgtgt cgtcgaactc ggtgtcttca tgtagcggaa gaaatcgctg
     5701 tccgggctca gtaccatcac gtcctgatta ccttcgaagc tcttctcgta agcgcgcaga
     5761 ctacgaatga acgcgtagaa atcagggtcc tggctgaacg cgtcggcaaa cagcttcgcg
     5821 gcttcagcat caccttcacc acgcatgata cgcccctgac gctcggcttc cgccagagtt
     5881 ttcgtcacct catagtcagc agccgcacgc agtttttccg cttcttcctg accttgtgag
     5941 cgatgacgac gcgcgaccgc ttcacgctcg gcgcgcatac ggttgtaaat cgcctcagaa
     6001 acctcggtcg gcaggttgat ctgcttaata cgcacatcga ccacttcgat acccaacgcc
     6061 gccatactgt tcgggttgat gaccggtact ttacctttgg tttccgccgt gacgcgttcc
     6121 gccgcttcgg caatcgcgtc atccgccgcc ggggtcgcca cttcatcatc agtgccggct
     6181 gaaccggagt tcagcgcgtc gcgcacttcc agagtcagac gaccacgaga atcggtcacg
     6241 atgtctttta cgtccaggcg accaatctca gaacgcaaac ggtccgagaa cttacgtttt
     6301 aacagcactt cggcttgcga aatatcgccg ccgccggtcg ccagatagta acggctaaag
     6361 tcgctgatac gccatttgat gtaggagtcg acaatcaggt ctttcttctc tttagtcaca
     6421 aagcgatcgg cctggttatc catcgtctgg atacgcgcat caagcatttt cactgattca
     6481 ataaacggga tcttaaagtg cagacccggc gcgtaaacca gcggtttgtt ctcatcgtca
     6541 cgcagaactt taccaaaacg cagcgtaatg ccgcgctcgc cctctttgac cacaaagacg
     6601 gacatgtaga gcactaccag cacgatgatg ataatcgcaa taactgactt acgcatcgtt
     6661 attccccctg acgctggtag tcgttacgct gcgcattcgc gcggcgttgg tccataatat
     6721 cgccctgatt tgaggacgac gtgttgcttg ctccgctggc gttagacttt gtggacggcg
     6781 gcaggcgcag caggttgctg gcgctattgt cgctctttgc cgccggcgca ttcccgcctt
     6841 tcagcatctg atctaacggc agcaccatta aattaccgct cttgtcgtta accagtactt
     6901 tacgggtatg gctcagcact ttttccatcg tttcaatata cagacgctcg cgcgtaatct
     6961 gcggcgcggc tttatattct ggcaaaatct tcgcaaaccg ggcgacttca ccctgcgctt
     7021 ccaggatagt ctgggtttta taggcacgtg cctcttccag aatacgctgc gcctgaccgt
     7081 tggcgcgcgg ctgaacttcg ttggtatacg cttccgcttc acgaatgtac tgctgctcgt
     7141 tttcacgtgc ggcaatcgcg tcgtcaaagg cggctttcat ctcttccggc ggacgcgcag
     7201 cctggaagtt cacgtccagc agggtaatcc ccatgttgta cggtttgata gtctcttcca
     7261 gctcgcgttg ggtatcgcta cgaataacgg tacgaccttc ggtcagaatg cgatccatcg
     7321 tgtatttacc aatgacgcca cgcaacgcgc tgtcggtggc ctgacgcagg ctatcgtccg
     7381 ggctggtcac gctaaacaga tatttctgcg gatcggtgac gcggtattgc acgttcattt
     7441 caacgcgcac gacgttttca tcagacgtca gcatcacgcc tgacgccgcc agttcgcgca
     7501 ccgcttcgac gttcaccggc gtgacgtcgt caataaatgt cggcttccag ttcagacctg
     7561 gctctaccag atggctgaat ttaccaaaac gcgtcacaac gccgcgctcg gcttctttaa
     7621 tggtataaaa accgctggcc gcccagataa tgactactgc cgccgcggcg atggcgacaa
     7681 tacggcctcc cagttgcgga cgcgggcctt gcgatgagct accgccgccg gaaccggtgc
     7741 ctttaccgcc cccaaaacca ccgagttttt tactcagctt acggaagata tcatccagat
     7801 cgggaggtcc ctgatcgcgg ccacctttgt ttccatttcc cccagagttg ctgccaggtt
     7861 tgctgcttcc ccacgggtcg cggtcctgtc cgttattacc gggctgattc cacgccatgt
     7921 ttgtgctcca tatttgttat gcggtgatcc ccgttgtctt tcgacctcag aggataaggc
     7981 gaaattactc catgcttcag acgaaccgcc gttacagaca tcatctttca ggctacgcct
     8041 tgagtggcgg cttttttacc ccaggtcact tcgttgtgag ctcctgaaat tctctcagct
     8101 accgcttcaa tacgacctga atgacttcgc gtctagatca cgtattcgat caacgccggt
     8161 tcttgtttac agaggcgacg ccagtcgaca atcggcattc gtacctgcag actgacgcta
     8221 ccgtcttcct ccatccactc tttttctatt gcctgaagct gataaaaccg gcttctcaga
     8281 cgcccttcct gcggcagcaa acgcagcgta tgctgcgcca cctcgccgga aagacgctcc
     8341 gtcaaagcct gaaaaagctg tggtattccc acgccgcttt gcgctgaaag ccaaacgcgg
     8401 atgggtttat tctcttcatc tctgtcgata cgcggttcaa agtcgtccag catatcgatt
     8461 ttgttcatca ccattaaggt ggggatttcg tgagcgtcaa tctcttcaag aacggtgttt
     8521 accgcctcga tgttttcctg cacacgaaca tccgccgcat cgaccacatg cagcagcagc
     8581 gtcgcctgac gcgtctcctg cagggtagct ttaaaggcag ccaccagatc gtacggtaaa
     8641 tggcggataa agcctaccgt atccgccaga acggtttcac cgacatccgc tacatcaata
     8701 cgacgtaacg tggggtccag cgtcgcaaat agctgatctg ccgcatagac ccgcgcttca
     8761 gtgatctgat taaaaagggt ggattttccg gcgttggtat agcccaccag cgataccgtc
     8821 ggaacgtcgg ccttgatgcg cgactgccgc ccctgctcac gttgcttctc aactttctcc
     8881 aggcgcgact gaatctgcac aatgcgatta cgcagtaaac gacggtcggt ttcgagctgg
     8941 gtttcacccg gaccgcgcaa accaatcccg cctttctgac gttcaaggtg ggtccagcca
     9001 cgcaccagac gcgtagccag atggcgtagc tgcgccagct caacctgcaa cttaccttca
     9061 tgggtacgcg cacgttgggc aaaaatatct aagataagac cggtgcgatc gataacccgg
     9121 cactcgcaca aacgctccag gtttcgctcc tgggctggac tcaatgcatg atcaaacaat
     9181 acgaccgctg cgccagtcgc tttcacggct tccgcaattt caactgcctt accttcacct
     9241 acaaagtact tcgggtgcgg tgctttacgg ctaccggtaa tcacctgcat tgcttcgaca
     9301 ccggcggaag agaccagaga ttcaaactcc tggaggtctt ccatatcttt gtcttgcgaa
     9361 aaatagatgt gtaccagtac cgcctgctca ccggcatcat aacggtcaaa caagcgtaaa
     9421 ccctcttaat aaccagcggg ggcgattatc cgacgccccc gacatggata aacagcgcgt
     9481 gaacttattc agtctcttcg ctgtcctgtt gcgcagtaga accctgcgcg ttgctaccgt
     9541 gatggtagtt attgctggcg ccgccaccgg cattgttgct gtgatgggaa accgggcgag
     9601 acgggacaac agtagaaatc gcgtgcttat aaaccatctg gctgaccgtg tttttcaaca
     9661 ggatcacgaa ctgatcaaag gactcgattt gaccttgcag cttaatacca ttcaccaaat
     9721 aaatagaaac tggaacacgt tcccgacgca atgcgttcag gaacggatct tgtaaagatt
     9781 gccccttagc cattctcttt tccttatatg cttatttgta ctttgaacct ttcgattctg
     9841 aaaaattgcg cacgatacgt ctcaattgta cacattcagt ctgcgatagc accaacaacc
     9901 tgtaatactt cttttcgcgc ccgatcggga ttctcactgt caagccagcg caccccttcc
     9961 caaccgcgca accaggtcat ctggcgcttc gccaactgtc tcgtggagca aacacctcta
    10021 taaaccattt catcatatga gatttcgccc tcaatgtatg accacatctg gcggtatccc
    10081 acacaacgga tggaaggcaa gtccgtatgc aaatctcctc gggcaaaaag cgcccggact
    10141 tctgcttcaa aacctgaagc caacatctga tgaaaacgca gttcaatgcg ctgatggagc
    10201 agttcacggc tcgctggggc gatagcgaac tgatgcacct ggtacggtag cgcgtctcct
    10261 gacgtttgcg ttagctccgt taaagtttta cccgaaatga aaaaaacttc cagtgcccgg
    10321 gaaagtcttt gcggatcatt tggatgaatt cgcgcggcgg caaccggatc tatctcctga
    10381 agttgctgat gcaacgcctc ccatccaagc tccgctgctt gctgctctat ccgggatctg
    10441 acttccggat ctgctgaagg cagcggcgat aacccttcca gcaatgcctt aaaatacagc
    10501 atggtaccgc ccactaacag cgggatacgc cccgcagcgg tgatctccgc catttgcgct
    10561 aacgcgtcgc ggcgaaaatc cgccgccgaa tacgcctgcg acgggtcgcg tatatccagc
    10621 agtcgatgcg gcgccgcttt cagctcatcg gcattcggct tagccgtgcc aatatccatt
    10681 ccccgataaa tgagggcgga atcaacgctt atcaactcta ctggcaaaac tttacgcagt
    10741 tctatcgcca gcgccgtttt gccggaggcc gtcggcccca tcaaaaatat cgccttaggc
    10801 aggctcacct tgcttacatc attcatgctt cagggcgttc atcgccgaat gtaaatcaac
    10861 aggttgtaac aggccacccg gcggcgcttt taccagctgc ggacatagcc gctcaacatc
    10921 cgccagcagc gatatggcct gcgccatcga ccactgcgga tgttcgctct gcacattacg
    10981 cgctatccat tgtgcaatat tgaccgttgc aaatgtggtc tgttgcgcca ggtagcctat
    11041 cagttcagga atcaagattt gtaaattttg ttgtcgtaag ggtaaaggca ccgcccgaat
    11101 ggtcacatgc tgcgcatctg actgaaattc aatacccaat tctcccaaca aagattgggc
    11161 tttttgcagc gcggcttttt catcggcgct cacttttaaa cgcagcggaa tcagcaacgg
    11221 ctgcgcgcaa accggacttt gacccggtgt aagctgcgcc tgacgcagcc aacgctccgc
    11281 aaccggcagc gacaagagct ggatagtccc cgcgtgttcc agcaacgcgc agtcaccgcc
    11341 gactatcgtc agtacgcgac caaaactctg gctatgtccg tcaagcgcag gcgcaaccgg
    11401 ctccggcgcg gggctcgtcg tcggcgtctg taaaagcgtg cgataaacct cgccctgctg
    11461 cttctgatag cctggctgcg cgtgcggcca accacctgcg gactgacgcc cgccgttacc
    11521 gcccgatgcg ccgtcggaat aacgcggtgt cgcgggctcg cgcgccgcag ttggctcggc
    11581 gggtacagca aaatggttgc gcccggcggc gatacgattt tccgggacat gccgcggcgc
    11641 tggcgcaatc tcctccagcg gcagcgtcgt ttccgtctgc tgttgtagaa cgctcagcac
    11701 cccttgatag atgaagtcgt gcaccagccg cgattgatga aaacgcactt cgtgcttggc
    11761 gggatgaaca ttgacatcca cctgatgcgg gtcaatctcc agatacaaca caaacgcagg
    11821 ctgttggtcc gcgcccagtt tatcttcaca ggcctggcga atggcatggt tgatcaagcg
    11881 gtcgcgcatc atgcggccat tcacatagca gtactggatc tccgttaacg ccgtggtggt
    11941 gtgattcgga tcggcgaccc agccgcgcag ggtcagatcg ccatgctgcc actcgatcgc
    12001 cagtgcctgt tcgagaaacg gcgtgccgca gatggcgctt aaccggcgct ctttttgccc
    12061 gtcctttgcg acagcgcgat actgccgtac caatttgccg ttgtgcgaca ggttaagcgt
    12121 gacgtcaaaa cgggccaatg caatacgacg gatgatctca tcgatgtgat taaattccgt
    12181 tttttcggta cgcatgaatt tgcgccgggc gggcgtatta taaaagagat ccagaacttc
    12241 cagggtggtg ccgaccgggt gcgcggcggg ttttaccgtc acgtccatgt cgcgcccttc
    12301 cgcatacgcc tgccaggctt ccgcctgctc cgccgtgcgc gacgttagcg tcaaacgcga
    12361 gaccgaactg atactcgcca gcgcttcgcc gcgaaatccc agactgataa tcgcttccag
    12421 atcgtcaagc gaggcgattt tactggtggc atgacgggcc agcgccagcg ccagctcctc
    12481 ttttttaatg ccgcagccat tgtcgcgaat acgaataagc ttcgcgccgc cacgctcgat
    12541 gtcgatatca acgcgggtgg cgcctgcatc cagactattc tctaccagct ctttaacaac
    12601 cgacgcaggg cgttccacca cttcgccagc ggcgatttgg ttcgcaagct gcggcggcag
    12661 aacctgaatc ggcatgaaat ctccttaatt cgcggcggtt atagcgccag gctggttggt
    12721 actggccgtc tggcctgggc tgccctgcgg cgcagactgg atcggatgcg ctgcaaagta
    12781 cttacgcaac ccccggtata tagcgtcagc aatctgctgc tgatagcggt cgctcgccag
    12841 caatcgttct tcgccgtgat tactgataaa acccgtctcc accaaaatgg acgggatatc
    12901 cggcgaacgc agcacgccca ggctcgcgtg ttccgggcga cgtttatgca gcgaccccac
    12961 gccgtcgagt tggcttagta cgttcgtcgc cacatcatac cctacccgct gcgaatgacc
    13021 gaattgcaaa tccagtaccg cctggctcag gtaagggtct gactgactgt tcgtcagcac
    13081 atcgccagcg ccgcctaaca gttcggattg cttctcatgc tgctcaagcc agtttgccat
    13141 ttcgctattc gcgcgacgat tggacaatac ccagacggag gcgccggtgg cgtcgcgatt
    13201 tggcgcggca tccgcatgaa tagagacaag gaagttggcg ttttgcttac gcgccacatc
    13261 agaccgcccc atcaccgaaa taaaatagtc gccgtcacgc gtcagcacgc ctttaaacat
    13321 cggatcgtta ttcagcaatg tgcgtaactt acgcgcgatg gcgatggtga catttttctc
    13381 gcgcgtaccg cccgggccta tcgcaccggg gtcctggcct ccatgtccgg catcaatagc
    13441 aatcaccact ttatcgccag cgcctgccga cgcgcgcgcc gcaggccgcg taacggtgtt
    13501 gctgctggtt acgccggtca ggcgatcatc agaagattta aacggattac gggcaggctc
    13561 cgtcgggcgg ggcgcgcttt caacccgttt cgcgacgaca ggcggcggcg gcggcggaac
    13621 atcggcatta atggtgaaaa tgaccgtata gttgccgccg ttttgccgct tcaccgcctc
    13681 ggttttacca ttttccgtca gatcgacaag cagccgtaaa gattgcgcat ctttcggcgt
    13741 tccggcacgg atcgttttta ccagattgtt accgctaaac tgaagcggca gcccctgaat
    13801 cacgccggtc tgcctgatat ccagcgccac ggtccgttta ccgtcctgtg agtaagcata
    13861 ttccggctcg ccgataaaac tcagcgtaat gcgcgcctgc tgctcgccgt tggacacctg
    13921 aatatcagag agactggcgg cgcccgcctg cgcgcacagc aggattaagg ctgctattac
    13981 ggcatttttg atgcgataaa tcatcccgcc acctttatag ctaatcggct aaacgcgcca
    14041 gtaacgaatg acccgatgag gataccgcgc ttacgcgagc ctcacgcccc tgcgcctggt
    14101 aatcaatatg gatttcgacg tccgggtcgg ggagaacgcc tttaccttgt tgcggccact
    14161 ccaccagaca aatggcgtcg ttggcgaaat aatcgcgaat gcccataaac tccagctcct
    14221 ccgggtccgc aagacggtat aagtcgaagt gatataccat catgttatca agcgcataag
    14281 gctctaccag cgtataggtg gggcttttta cattaccgtt atggcctaac gcctgtaaaa
    14341 atccccggct aaacgtcgtt ttaccggcac ctaaatcgcc atacagataa ataacggtcg
    14401 cgccatcaca ggcgttggct acccgttgcc ccaggtctag cgtcgcctgt tcgtcaggta
    14461 gcggaattac tcgattcatc atggtttacg tcaatcacat cagggttaac aatacgccgc
    14521 agcgtagtaa aaagatcggt cgccaacatg ccgcgagcgc cataacgcgc tgccagtaag
    14581 tccgccgccg cgccgtgagc cacacatccc acacatgccg catcatacgg ggtaaacttc
    14641 tgtccgagca atgcgccgat gatgccggac aggacatcgc ccatcccgcc gctcgccatc
    14701 cccgcattac cagcgtcaat gatagccaga gggtggtgtt cagcggcaat aatcgttcct
    14761 gcgcctttta acacgaccac gcctccatac cgttttacca gacgctgtgc tgaaagtaag
    14821 cgatcacttt caatttctgc cacagaacat cctaacaggc gggccgcctc tcccggatgc
    14881 ggcgtaatca cgcgattgtg acgtttatca ggattgattg ccagtaggtt caacgcatcc
    14941 gcatcccaca gcataggttt acggacgttt tctactttct gtaaggcttt tttgccccat
    15001 tcctgctgtc caagccccgg gccgatcacc acaacgtcag cccaggtcag gctctcttcc
    15061 agcgactgag gcgtgagttc atgtaccatc agttccgggc gggccgtcag caacgacgcg
    15121 atgttttcac cgcgagtcag tactctgacc aacccagccc ccgtacgcag cgccgcctcg
    15181 ccagccatcc gaattgcacc cgctgttccc tgatcgccgc cgataatcgc cagacgacca
    15241 tgatcgccct tatacgaggt cggtcgacgc ggcgttaacc attgccccaa ctgcgtcgcg
    15301 tcaaaacgcc ggagcggcgg cgtctggctc gccagccagc cttccagccc caacgcgtca
    15361 taatgcaata tgccggtaac gtcacgcgct ttgccggtca gcaggcctgg tttcagggcg
    15421 ataaacgtga ccgtatgcgc ggcgcttatc accgcgccag gcgtggtgcc cgtttgcgcc
    15481 agcaggcctg acgggatatc gacggcgaca accggcgcag gatgggcgtt cgcctgttca
    15541 atcagaccgg ctaccggatc gcgcggctcc tgggctatgc cggtgccaag cagcgcgtcg
    15601 ataatcagat ccgtcgcttc cggccagata atatcggcag catggataat gccgccggca
    15661 ttcagccagg catcgcgcgc ctgcgccgct tcttcaggta acggtttgtc gctctcctgc
    15721 gccagcaacg ttacgctaat gcccgccgct tgcgctagtc gcgccacgac gtaaccatcg
    15781 ccgccgttgt tgccatgacc acacaacacc agccagtgtc gggcgtcagg gtaactgtca
    15841 cgggctaccc gaaatgccgc gtcgccagcg cgcagcatca attcatagag tgtgagtccg
    15901 aaggcatccg ccgcatcgcg ttccagccgt ttgatgtcat cggcgggcca aatggagtgt
    15961 ggtatactta cagggttttt cttcatgtta tggtccatca tgtcaaagcc cctcgatctc
    16021 aatcagttag cgcaaaatat taagcagtgg gggctggagc tgggctttca gcaggtcggt
    16081 attactgata ccgatctgcg cgcatccgaa cctgcgctgc aggcgtggct ggacaaacaa
    16141 taccacggcg agatggcatg gatggcgcgc cacggtatga tgcgcgcccg gcctcatgaa
    16201 ctcttacccg gtacgctacg tgtcatcagc gtgcgcatga actatctgcc cgccaacgcc
    16261 gcgtttgcca gtacgttgaa ggatcccacg ctgggctacg ttagccgata tgcgctgggg
    16321 cgtgattatc acaagctgtt acgcagccgt cttaaaaaac tgggcgagca gatccagcag
    16381 tactgcggtt cgctgaattt tagaccgttt gtcgactctg cgcctattct tgaacgccca
    16441 ttagcggaaa aagccggact tggctggacg ggtaagcact cacttatcct taatcgggag
    16501 gcgggctcat tctttttcct gggggaattg ctgattgatt taccgctgcc ggtcgaccag
    16561 ccggtcgagg aaggttgcgg caaatgcgtc gcctgtatga ccatttgccc gaccggggcg
    16621 attgtcgaac cgtatacggt ggacgcgcgg cgctgtattt cttatctcac cattgagctg
    16681 gaaggcgcta ttccggaagc atttcgccca ctgataggta accgtattta cggctgcgat
    16741 gactgccagc ttatctgtcc gtggaatcgt tactctcagt tgaccgacga agcagatttt
    16801 agcccacgca aggcgctgca taacccagat ttgcttgagt tgtttagctg gagcgaagcg
    16861 cagtttctga aagtcactga aggttctgcg attcggcgca ttggccattt acgctggctg
    16921 cgcaatgttg ccgttgcgct ggggaatgcg ccgtggagta atgccgtcat tacggcgttg
    16981 gaaagccgca agggtgagca tccacttctt gatgagaata tcgaatgggc gattgcgcaa
    17041 caaattgaaa agcggaacgc ctgcatcatt gaagtgcagc taccgaaaaa acagcgtctg
    17101 gtcagggtga ttgaaaaagg gctggtgcgc gatgcctgaa ttattcacag gctgtgtata
    17161 aaaataaaaa cacattgcga ttcaagaggg aaaaaaggaa cagacaataa cgctaacgtt
    17221 ttgaaatctt attttttcta tatttttcag taaattatag aaattctacg cgtcaggtat
    17281 aattttttgc attccaggag taatgggccg tcctgtggat aagtctgttt acaaggatct
    17341 gacgaaagcg gaacaaaacg tgccccaacg cgatattcgt tgtggataat tttactgtag
    17401 ataagaattg gagcgggaaa cgagactcga actcgcgacc ccgaccttgg caaggtcgtg
    17461 ctctaccaac tgagctattc ccgcataatc ttcgtctttc gaaccgctac tgccttggct
    17521 gccttcactc gcctgagtca cttacttcag taagctcctg aggactcatt cagttgccgc
    17581 cttgtcgcaa ttcgaaatcc tgcgattggt ggtttgtact taacaagtac tttcaaattt
    17641 tggagcggga aacgagactc gaactcgcga ccccgacctt ggcaaggtcg tgctctacca
    17701 actgagctat tcccgcaaat ttgttgctgt cgtaattcgc atttctgcgt cgttacggga
    17761 ggcgcattat acgagaaatc catttagctg caagcccctg aacgcatttt ttcgcgattt
    17821 ttgtttgaat gctgattaaa tcaccaaaca agacaaaaaa cgagcaaagc gtgcgctatg
    17881 caacaaaaaa cttttcacgc cacgcctaaa ggcacagaat cagaatagca ccctgcgcca
    17941 aaaaaagaat agcacggtga ccacaacatc caattgatat cagggatcaa gatgaaaaaa
    18001 aacttattgt catgctgtta gccagcctct ccgttcacgc tgcttccgtt tccgccagaa
    18061 cattacattt tggcacctcc gccacctatg cgccctatga gtttgtcgat gccgataata
    18121 aaattgttgg tttcgatatt gatgtcgcca acgcggtctg caaagagatg caagcggagt
    18181 gctcattcac taaccagagc tttgatagtc tgatccccgg cctacgtttc aaaaagtttg
    18241 atgcggtgat cgccggtatg gatatgacgc ccaaacgtga gcagcaggtc tcctttagcc
    18301 aaccctatta cgaaggttta tcggcggtag tcgtcacgcg taaaggggct tatcacactt
    18361 ttgccgatct gaaaggcaaa aaagtcggac tggaaaacgg tacaacgcat cagcgctatt
    18421 tgcaggataa acaacaagct atcacgcctg tcgcctatga cagctatcta aacgctttta
    18481 ccgatctgaa aaataaccgt cttgagggcg tgtttggcga tgtcgccgcg attggtaagt
    18541 ggctaaaaaa caatccggat tacgccatca tggatgaacg cgccagcgat cctgactact
    18601 acggaaaagg gttaggcatt gcggtacgca aaggcaacga cgcgctattg caagaaatta
    18661 atgccgcgct cgacaaggtg aaagcgtcgc cggaatatgc gcaaatgcag gagaaatggt
    18721 ttacgcagta attcagtggc gggagagctg ccggatgaga cgctctggcg ttgccatccg
    18781 gcatgttacg cctcacagct taatgaaatg ctcgcggtag taagccagct ccgccaccga
    18841 ctcgcgaata tcatccatcg cctggtgcgt gccctgcttg gtaaagccgg ccagaatctc
    18901 cggcttccag cggcgcgcca gttccttgag cgtactgaca tccagatagc gatagtggaa
    18961 gtaagcctcc agttccggca tatatttaaa cagaaaacga cgatcctgac cgatgctgtt
    19021 accgcaaatc ggcgacttac ccgcaggcac ccacgttttc agaaattcaa tcgtcgccag
    19081 ttcagcgtct cgttcgccca tcgtacttgc tttaacgcga tctaccaggc cgctaccggt
    19141 atgggtgcgc acgttccagt catccattaa cgccagttgc gcatcggatt gatgtaccgc
    19201 aatcgtcggc ccttccgcca gaatgttcag gctggcatcc gtcactagcg tggctatctc
    19261 aataatgcga tcgcgttcgg ggtccagacc tgtcatctcc agatcgatcc aaatcaggtt
    19321 gttttcatcg gcactcatgc tattttccac ccttcagagg tcacattcac tgtgactata
    19381 ttcatctaca attgcgtgta tcatagatgt tttgcccact atgggcgacc aggagccagt
    19441 acgattgagc aaaaataaac tctccaaagg ccagcagcgc cgtgtgaacg ccaatcacca
    19501 gcgtcgttta aaaacgtccg cggagaaagc cgactacgat gacaacctgt ttggcgagcc
    19561 tgcagaaggt atcgtcatta gccgttttgg tatgcatgcc gatgtggagt ctgctgacgg
    19621 cgaggttcac cgctgcaata tccgccgcac tatccgttcg ctggtgacgg gcgatcgcgt
    19681 cgtctggcgt ccgggcaaag ccgccgcaga gggcgtcaac gtaaaaggca tcgttgaagc
    19741 ggtgcatgag cgcacctcgg tattgacgcg cccggacttc tacgacggcg tgaagcctat
    19801 tgccgccaac attgaccaaa tcgttattgt ctccgcgatt ttgccggagc tgtcgctgaa
    19861 tatcatcgat cgctatctgg tcggctgtga aaccctacag gttgagccgc ttatcgtact
    19921 caataaaatt gatctgctgg acgacgaagg tatggacttc gttaatgagc agatgaatat
    19981 ctaccgcaat atcggctatc gcgtgctgat ggtctccagc catacgcagg atggtctgaa
    20041 accgctggaa gaagcgttaa ccggtcgcat cagtattttt gccgggcagt ccggcgtcgg
    20101 aaaatccagt ctgctaaacg ctctgctcgg cttacagaac gagattctga cgaacgatgt
    20161 gtcgaatgtc tccggtctgg gtcaacatac cactaccgct gctcgtctgt atcatttccc
    20221 gcatggcggc gatgtcattg attcccccgg cgtgcgcgag ttcggcttat ggcatctgga
    20281 gccggaacaa atcacccagg gctttgtcga atttcatgac tatttgggac attgtaaata
    20341 ccgggactgc aagcatgacg ccgatccagg ctgcgccatt cgcgaggcgg tagagaacgg
    20401 cgctattgcg gaaacccgtt tcgaaaatta tcaccgaatt cttgaaagta tggcgcaggt
    20461 aaaaacgcgt aaaaactttt ctgatacgga cgactgacag atacgctagg cgtcgttaga
    20521 atcgtcccct tttttcagga taccggtata actgccggtt caggaacaac aatggcctgg
    20581 aggctacctt gttaaactca tttaaacttt cgctacaata cattctgccg aaactatggc
    20641 tcactcgcct ggcgggctgg ggcgcaagca aacgagcagg atggctgaca aaactggtta
    20701 tcgatctctt cgtaaagtat tacaaagtcg atatgaccga ggcgcaaaaa ccggataccg
    20761 ccagctatcg tacgttcaat gatttctttg ttcgtccgct gcgtgatgac gtgcgtccgc
    20821 tcaataccga tcctaacatc ctggtgatgc ctgccgacgg cgtgataagc cagttgggtc
    20881 gtatcgaaga agataaaatt ttgcaggcca aaggccataa ttacagcctt gaagcgttgc
    20941 tggcgggtaa ctacctgatg gcggataagt tccgcaacgg cacgtttgtg accacttacc
    21001 tctcccctcg cgactaccat cgcgtgcata tgccatgcaa cggcatcctg cgcgaaatga
    21061 tctacgtgcc gggcgatctg ttctccgtta actatctgac cgcgcaaaac gtccccaacc
    21121 tgtttgcccg caacgagcgc gttatctgtc tgtttgatac cgagttcggg cctatggcgc
    21181 agattctggt cggcgcaact attgtcggca gtatcgaaac cgtctgggcg gggaccatta
    21241 ccccgccgcg cgaaggcatc atcaagcgct ggacctggcc agaaggcgaa catgaagggt
    21301 ctgtcgcctt gttgaaaggc caggagatgg ggcgctttaa actgggttcc acggtcatca
    21361 acttatttgc gccggggaaa gtgaatctga tcgcgtcgct ggcaagcctg tccgttacca
    21421 aaattggcca accgctggcg acgtcgaccg aaacattcgt cgcgccggag gtggaacctg
    21481 ctccgctgcc ggcagaagaa attaaagctg aacacgacgc cagcccgctg gttgacaata
    21541 aaaaagacga cacctaatca agagagaatg ctgacgtgcg cctgattatc gcttttctga
    21601 tggcctggtg cctcagcacg ggggcgttcg ccgcaacggc ccccgacgcc aaacaaatca
    21661 cgcaggaact ggagcaggca aaagcggcga aacccgctca gccggaagcc gttgaggcgc
    21721 tccagactgc gttaaacgcg cttgaagagc gaaaaggctc gcttgagcgc gcgaaacaat
    21781 atcaacacgt tattgataat ttccctaagc tatccgccac cttgcgcgcc cagttgaata
    21841 atctgcgcga tgaacctcgc agcgtaccgc cagagatgtc caccgaagcg ttaaatcagg
    21901 agatcttgca ggttagcagc cagctactgg ataaaacccg cgaggcgcaa caggagcagg
    21961 agcgcgtcag ggagatcgcc gactcgctca gccagcttcc ccaacagcaa aacgacgccc
    22021 gccgccagct taatgagatt gagcgacgac tcggcgccgc aggcggaagt gccgcgctta
    22081 gccaggcgca aagtctcagt atgcaggcgg agtccgccaa actaaaagcg ttagtcgacg
    22141 aactggagtt ggcgcaactg tccgccaaca accggcagga actggctcgt ctgcgttccg
    22201 agctggcgga aaaacagagt cagcaattgg atgcgtatct tcaggcgctg cgcaatcagc
    22261 tcaacagcct gcgtcaacgt gaagcggaac gcgcgctgga aagcactgag ctgctggcgg
    22321 aaaacagcgc cggtttgccg gaaggcatcg tcgaacaatt taaagtcaac cgcgggctgt
    22381 cacaggcgct caatcaacaa gcgcagcgga tggatctggt cgcctcgcag cagcgacagg
    22441 ccaccagcca aacgttacag gtgcgtcagg cgctcaatac gctgcgggag cagtcgcaat
    22501 ggcttggcgt gtccaacatg cttggcgaag cgctgcgcgc gcaggtcgcc cgtctgccag
    22561 agatgcctaa gccgcagcag cttgatacgg aaatggcgca gctacgcgtt caccgtatgc
    22621 gctatgaaga attactcaat aagcaaccgc agctacggca aatacgtcag gccaatggac
    22681 aaccactgac cgccgagcaa aaccagattc ttgacgccca gcttcgcact cagcgcgagc
    22741 tgctcaactc tttgttacag ggcggcgaca cgctgatcct ggagttgacc aaactgaaag
    22801 tctccaacag ccaactggag gatgcgctta aagaggttaa tgaagcgacc caccgttatc
    22861 tgttctggac cgctgacgtt agcccgctat cgctctcctg gcctgttgat ttggttcagg
    22921 atttacgtcg gcttatctca ttagatacgt ttaatcagtt aggtaaagcc agcatcatga
    22981 tgctgaccag caaagagacg ctactgccgt tattcggcgc gctggcgctg gtcgggttta
    23041 gcctctattc acgccaacac ttcaaccggt tccttgagcg ctcggcctcg cgcgtcggga
    23101 aagtcaccca ggatcacttc tcgctgacgc tgcgaacggt gttctggtcg attctggtcg
    23161 cctcgccgct gcccgtcttg tgggcgacgc tcggctatgg tctacaggaa gcctggccgt
    23221 atccgctggc cgtcgccatc ggcgatggcg tgacggcgac agtaccgctg ttgtgggtag
    23281 tcatgatttg cgccgctttt gcccgcccta atggtctgtt tgtggcgcat ttcggctggc
    23341 cgcgaaaccg ggtagcgaaa gcgatgcgct actacctgat gagcattggg ctgatcgtgc
    23401 cgctcattat ggcagtgatc atgtttgata atcttaacga tcgggagttt tccggctcgt
    23461 tgggccgcct ttgcttcatc ctgatatgcg gcgcgctggc gctggtcacg ctgagtctga
    23521 aaaaagcggg catcccgctc tatcttgata aagaaggcaa cggcgacaac atggtcaaca
    23581 gcctgttgtg gaatatgttg atgggcgcgc cgcttatcgc gattctggcg gcggcggtgg
    23641 gttatctggc cacggcgcag gcgctactgg cgagactgga aacctcggtc gccatctggt
    23701 tcctgttgct ggtcatttat cacgtcattc gccgctggat gctgatccaa cgacgccgac
    23761 tggcttttga ccgcgccaaa catcgtcggg cggaaatgct ggcgcagcgc gcgcgcggcg
    23821 aagaagaacc ggcgcactcc tccagcctgg aaggcgcggt cgacatcgat gaaagtgaaa
    23881 tcgatcttga cgctattagc gctcagtcgc tgcgtctggt tcgctcaatt ctgatgctta
    23941 tcgccctgct atcggtaatt gtactgtggt cggaaatcca ctcggcattc ggcttcctgg
    24001 agaatatttc gctgtgggat gtcacctcta cggtgcaagg cgtggaaagt ctggagccga
    24061 ttaccctggg ggcggtgctc attgcgattc tggtctttat catcaccacg cagttggtgc
    24121 gtaatctgcc tgcgctgctg gagctggcgt tattacagca tctcgattta acgccaggta
    24181 ccggttacgc catcacgacc atcaccaaat atctgttaat gctgattggc gggctggtcg
    24241 gtttctcgat gatcggcatt gagtggtcga agctacaatg gctggttgcc gcgctcggcg
    24301 ttgggcttgg ttttggcctg caagaaattt tcgctaactt tatctccggc ctgattattt
    24361 tgtttgaaaa gccgattcgt atcggcgata cggtgaccat tcgcgatctc accggcagcg
    24421 tgaccaaaat caatacccgc gccaccacca tcagcgactg ggatcgtaaa gagattatcg
    24481 tgccgaataa agcctttatc accgaacagt ttatcaactg gtcgctgtct gactccgtta
    24541 cgcgcgtggt gttaaccatc ccggcgccgg cggatgccaa tagcgaagag gtgacgcaaa
    24601 ttctgctgac ggcggcgcag cgctgttctt tggtgcttga taacccgccg cctgaaatct
    24661 ttctggtgga tctccagcag ggtattcaaa tttttgaact gcgtatctat gccgcggaaa
    24721 tgggacaccg tatgccatta cgccatgaga tccaccaatt gattctggct ggcttccgcg
    24781 agcacggtat tgatatgccg ttcccgccgt tccagatgcg tctggagagt ctcggcggta
    24841 aacaaacggg gagaacgtta acgtcagcgg gtaaaaccag ccgcccggcg gggagtttgt
    24901 agcgcatgat cccggcaaga aatgccggat gcgccccgtc gggtcttatc cggcctacgg
    24961 gccgacaatt aatctgtagg cccgataagc ttgcgccatc gggcatttca tcgcaactca
    25021 cagacatttt cggacttatt atgcgtccag atcggcaaca ggcaggttaa tttcgctata
    25081 gcgcattcgg aataaatcgc cgtaacccac cagttctccg cgaaatacga ggcatcttac
    25141 aacatacgcg caataaatat ccgacacatg tttccactta tcctcatcgc gatcccttaa
    25201 cgtgccaata gtcattccta ctaccatcgc aacctttcga cgtgcaacat gaacggaaga
    25261 aagaataacc ttttctattt caaggatatc ttccggagta aaattgagtg ccctaatctc
    25321 atcttccgtg ataatcgggt ctctcgaact atcattcatc acgttctcca tagggcaata
    25381 aacgccggat gcgacccgtg gggccttatc cggcatacgg cctttactcc gccgcccact
    25441 ccggatcagc gctcatgcgg ctgctgtaat tctgataaat cgccatcgcc agcagcgaga
    25501 agaagatcgg gccgccgatc atccacaagg cgctgtccca gtccccagct tcaatcactg
    25561 gctggatgat ggtaaagacg ttggcaaacg tcaccaccag caccacaaca cccgtcgcga
    25621 ccagggtaga ggctttggtt ttaaagagaa caaatggccg ctccagatcc tgacgcgctt
    25681 taaagaaggg aaatgccagc gcaaggaaca ggtatggcaa ggtcattgag acgttcgcca
    25741 tcagcgtgag tttgttataa aacgccgatg cggtgtcacc gccaaaagag accagcaaaa
    25801 taaacagact caccagcacg cactgtagcc acatagcggt cgccggcata ccgttagcgt
    25861 tcagtgtcgt catcggcgcg ggccacaacg cttttggcgt cccctgaata atggctttca
    25921 gcggtgaata gctcaacgta aaaaacgcgc cggtataagc cagaaacata gaaaggccgg
    25981 tgatacgcgc aaaccagacg cccaccgtca tcgcagcttc cggagaaagg tttaacgcgt
    26041 tacctaatgt cgtgcctaaa ctcgacatca gaatgtaggt gatattccct aagttaacgg
    26101 cgctattact taatatctgt tgccagttag tactgacgcc ccataaaaag atcgccaaag
    26161 aataaccaat tgaaatcaca atggccgcga aaacaatacc tttcgcaaaa ttcttttccg
    26221 gtttctcggt tttatccacc agtccgccga cagcctcaat accgccgtaa gcaaaaatag
    26281 caaataccac aaatgacaac attgccaggc cggagtgata acccggattc ggtgacgagg
    26341 taaaattaat ctcttgtgca aaatgcccac catttaataa caaaatagcg acactcacta
    26401 acaataaaac taaattaaga cacattacgg caatacctcc gaccgccgta attcgcgcaa
    26461 ttttattgat ccctctggcg gcgacacacg tcaccagaat catccagccg acggcgagca
    26521 gcccgacaac ctgcgtaggc tcaagccctg caatacgcca gtgctgcgtc atatcggcgc
    26581 caaaaacaaa agtagaaaac ggtacccaaa tttttgccgc cgtacttacc atccatatga
    26641 catacgatga aaaccacata aacgtgccaa taaacgcgta acgtggcccc acgctattat
    26701 tcatccacga atagatcccg ccctcttctt tgcgataagc ggaacccatt tcagccatca
    26761 ttaaggcgaa tggaataaaa aacagcaagg cagaaaatat ataccacggg attgcgctat
    26821 accccattaa ataaaacgcc gacgggctat tcgcaaaacc aaaaacagaa gtaaaaatca
    26881 tcaggataag cccaataagg ctcatctttt ttatcgtgtg ggtcattcaa ccatccctta
    26941 cgctcgagcg cgtttgccag acgccgctca ccgattgacg ccgccttctt ttttacgaag
    27001 gtcagcgata aaaaaatcaa cacaggattg atacctaaat ggcatcaaag ttccagcctt
    27061 atgttgtggc aaacagagga taattgaaaa aatatgctac aaaatggcgc ttatttcgcc
    27121 attttatctc gcgaaagagt gaatttcaga tttacgcccg atcgaccgta aaagcaatca
    27181 cgtccgccag gctttctgct cccagcgcca gcatcaccag acgatcaaca cccagcgcca
    27241 cgccggaaca atccggtaga ccggcggcca gcgcatccag tagattttgg tcaatcggct
    27301 gctgcggcag accgcgcgcg gcgcgcttac gattgtcctg ttcaaagcgc tgttgttgct
    27361 cacgtgcgtc cgtcagttcg tggaaaccat tcgccagctc aatacctttg tagtacacct
    27421 caaagcgctc ggcgacgcga tgatcctcgg tactgatttg tgccagcgat gcctgactgg
    27481 ccggaaagtg ataaataaag gtcggctttt ctttacctat atgcggctca acccccatcg
    27541 tgaacagcag ttgcagcaac gtatcacggt cttcttccgt atcggcgata ttgcttaaat
    27601 caagctttgc cgccgcctca cgcagctgcg ttttatctgc tgataacggg tcaatctcca
    27661 gatggcgcag aaacgcctgt tgataggaga gactttccgc aggttgacaa tccagcactt
    27721 gctgaagcaa atcatccact tcattcatca ggcggtacat atcgtaatgc gggcgatacc
    27781 actccagcat ggtgaattcc ggattatgat gtcgtcccat ctcttcatta cggaaactgc
    27841 ggcatagctg gaaaaccgga ccgcaccctg ccgccagcag gcgtttcata tggtattccg
    27901 gactggtcat taaatagagg ttgatcccct gggaatggcc aggtccgacg aaacgcgttt
    27961 cgaacgggaa cagatgaatg tctgtgaccg tcgcctgact catgcagggc gtctcaacct
    28021 caagcactcc acgatcggca aagaaacgac ggatttccgc cataatcgcc gcacgtttta
    28081 ataaattggg gatggacgcg ctcggctgcc aggttgccgt ttcgctcatg attctttctc
    28141 cagtttaaga caaggtcacg aagtctactc gcaacgcgcg ggcgaaacaa attttgcgca
    28201 ggcgtatcgg gtgccttctg gagggtaaaa aaagtgattt cagatggttt agtaattaaa
    28261 ttaatcaaaa tcaatgataa ttcatccctc tgatacgcta aaaaaatcga acacgtcaaa
    28321 tttccctcac atccctgaga ctatactgtt gtacccataa aggagcagtg gaaacgcatt
    28381 catacttcgc agaacccaga ggctttatct ggctgcgcga gggtgaaatt acaataatct
    28441 ggaggaatgt cgtgcaaacc tttcaagccg atcttgccat tataggcgct ggtggcgcgg
    28501 gattacgtgc tgcaattgct gccgcacagg cgaatcccaa tgctaaaatc gcactgatct
    28561 caaaagtgta cccgatgcgc agccacaccg tcgctgccga agggggttca gccgctgtcg
    28621 cccaggatca tgacagcttt gactaccatt ttcacgatac ggtagcaggc ggagactggc
    28681 tgtgtgagca ggatgtcgtg gattactttg tccaccattg tcccactgag atgacgcagc
    28741 tggagcaatg gggctgcccg tggagccgcc gtccggacgg tagcgttaac gtgcgtcgct
    28801 tcggtggtat gaaaatcgag cgtacctggt tcgccgcgga taaaaccggc ttccatatgc
    28861 tgcataccct gttccagact tccctacagt tcccgcaaat ccagcgcttt gacgaacatt
    28921 ttgtgctgga tattctggtt gatgacaacc atgcgcgcgg cctggtggca atgaacatga
    28981 tggaaggcac gctggtacaa atccgcgcca acgccgtggt catggcgaca ggcggcgcag
    29041 gccgcgtata ccgctataac accaacggcg gcatcgtcac cggcgacggg atgggcatgg
    29101 cgctgagcca cggcgttccg ctgcgtgata tggaattcgt tcagtatcac ccgaccggcc
    29161 tgccaggttc cggtatcctg atgactgaag gttgccgcgg cgaaggcggt attctggtca
    29221 ataaaaatgg ctaccgttac ctgcaagact acggcatggg ccccgaaacg ccgctgggcg
    29281 agccgaaaaa caaatatatg gaactggggc cgcgcgacaa agtatcccag gctttctggc
    29341 acgaatggcg taaaggcaac accatctcca cgccgcgcgg cgatgtggtt cacctcgacc
    29401 tgcgtcatct cggcgagaag aaactgcatg aacgtctgcc gttcatttgc gaactggcga
    29461 aagcctatgt cggcgtcgat ccggttaaag aaccgattcc agtacgtccg accgcgcact
    29521 acaccatggg cggcattgaa accgaccaga actgtgaaag ccgtgtcaaa gggctgtttg
    29581 ccgttggcga atgctcctct gttggcctgc atggcgcgaa ccgcctcggt tccaactcac
    29641 tggcggaact ggtggtgttt ggtcgtctgg ctggcgaaca agcaatggaa cgcgctgcta
    29701 cggcaggcgc cgcaaatagc gccgcgctcg acgcccaggt tgccgatatt gaacagcgtc
    29761 tgaaaaatct ggtgaaccag gaaggcaacg aaaactggtc gaagatccgc gatgagatgg
    29821 gtctgtctat ggaagaaggt tgcggtattt accgtacccc ggaactgatg cagaaaaccg
    29881 ttgataaact ggccgagctt caggaacgtt tcaagcgcgt acgtatctcc gatacttcca
    29941 gcgtgttcaa cactgacctg ctgtatacca tcgaactggg tcatggtctg aacgtggcgg
    30001 aatgtatggc gcactctgcg ctggcgcgta aagagtcccg cggcgcgcat cagcgtctgg
    30061 atgaaggctg taccgagcgc gacgatgtga acttcctcaa gcacaccctc gccttccgcg
    30121 atgctgatgg cacgacccgc ctggaataca gcgacgtgaa aatcaccacc ctgccgccag
    30181 ccaaacgtgt ttacggcggt gaagcggaag cagccgataa gaaggagaag gcgaatggct
    30241 gagatgaaaa acctgaaagt tgaggtggtg cgctataacc cggaaaccga taccgcgccg
    30301 cacagtgctt tctatgaagt tccttatgat gaaacaacat cgctactgga cgcgttgggc
    30361 tacatcaaag ataacctgtc gccagacctg agctaccgct ggtcctgccg tatggcgatc
    30421 tgcggctcct gcggcatgat ggtcaacaac gttcctaaac tggcgtgtaa aaccttcctg
    30481 cgcgattaca ccaacggtat gaaggtggaa gcgctggcga acttcccgat tgagcgcgat
    30541 ctggttatcg atatgacgca ctttatcgaa agcctggaag cgatcaaacc gtacattatt
    30601 ggcaactctc gcacgccaga tcaggggccg aatgtccaga ccccggcgca aatggcgaag
    30661 tatcaccagt tctccggttg catcaactgt ggtctgtgct atgccgcgtg cccgcagttc
    30721 ggtctgaatc ctgagtttat cggaccggct gcgattacgc tggcgcatcg ctataacgaa
    30781 gatagccgcg atcacggtaa gaaggagcgt atggcgcagt tgaacagtcc gaacggcgta
    30841 tggacctgta ctttcgtggg ctactgctcc gaagtctgtc caaaacatgt cgatccggct
    30901 gcggccattc agcagggtaa agtggaaagc tcgaaagact ttcttatcgc caccctgaaa
    30961 ccacgctaag gagtgcaaca tgacgactaa acgcaaaccc tatgtgcggc cgatgacgtc
    31021 cacctggtgg aaaaaactgc cgttttatcg cttttatatg ctgcgcgaag gcacagcggt
    31081 gccggcagtc tggttcagta ttgaactgat tttcggtctg tttgcgctca aacacggcgc
    31141 ggaatcctgg atgggattcg tcggcttttt acaaaacccg gtggtagtga tcttaaacct
    31201 gatcaccctg gcggccgcgc tgctgcacac caaaacctgg tttgaactgg cgccgaaggc
    31261 ggccaatatc attgtaaaag acgaaaaaat ggggccagag ccaatcatca aagggctttg
    31321 ggtggtcact gcggtagtca ccgtagtcat tctgtatgtt gccctgttct ggtaaggagt
    31381 cccggatgat taatccaaac ccaaaacgtt ctgatgaacc cgtattctgg ggactgtttg
    31441 gcgcaggcgg tatgtggggc gcgatcatcg cgccggtgat cgtgctactg gttggcatca
    31501 tgctgccgct ggggctattt ccgggcgatg ccctgagttt tgagcgcgta ctgacgttcg
    31561 cccaaagctt tattggtcgc gtttttctgt tcctgatgat cgtgctaccg ctatggtgtg
    31621 gcctacaccg tatgcaccac gcgatgcatg acctgaaaat ccacgtgcct gcgggcaaat
    31681 gggtcttcta cggtctggcg gcaatcctga ccgttgtgac ggcgattggc gttatcactc
    31741 tctaagttgc cacgacgccc tcttatctac ccgataagag ggcatttttt cttttcctgc
    31801 ctctcatttt cccgccaggt tctacactta gaaaaaacac tggaaggaaa aacgctatgc
    31861 gcttgctgcc cgtcgttgct gcggttactg cggcattttt ggttgtcgcc tgtagttcgc
    31921 ctaccccgcc taaaggcgtt accgtggtaa ataactttga tgccaaacgt tacctcggca
    31981 cctggtatga gatcgcacgc ctcgatcatc gatttgaacg tggactggaa caagtcacgg
    32041 ccacctatag tctgcgtgac gatggcggga ttaatgtcat caataaaggc tataacccgg
    32101 ctcgggaaat gtggcaaaaa acagaaggca aagcgtattt taccggtagt ccaaaccgcg
    32161 ccgcgctcaa ggtctctttt ttcggcccgt tctacggcgg ctataacgtg attgcgcttg
    32221 accgggaata ccgtcatgcg ctggtgtgcg gcccgaatcg cgactatctg tggatactct
    32281 ctcgcacgcc aacgctttct gaggaaataa aacagcaaat gctggccgtc gcgacccggg
    32341 aggggtttga cgtcaataaa ttaatttggg taaaacaatc aggttcgtag caatgtcagc
    32401 gacgaattaa tgcgcactga gttttagccc aatgataccc gcgacgatca agccaagact
    32461 gagcaaacgc gccggtgagg cagactcgcc cagcagaagg ataccggtga ttgccgcccc
    32521 aacggcgccg atgccggtcc agatggcgta cgccgttcca acaagcagcg ttttcattgc
    32581 ccaggaaagt aacgccatac tgataaccat ggccgtaatg gtgataatac tgggggtcag
    32641 acgagaaaaa ccgtgggtat acttcaggcc gacagcccat accacttcaa gtaaaccagc
    32701 gattaataaa atgatccagg acatagcagg ctccagataa ttaatggggc cgtccccggt
    32761 gagaatagcg tttacaggtc gtcctgtaac gtatacggat gaaaagccat tcttgcctga
    32821 gagaaaatga atttcaacct ttttattttt ttccgtctaa aggcgggaat tggccctttt
    32881 aagccgcgta gttttcgcat ttagcgccca caggagttct ctatgatgga acgccttctg
    32941 ggaaagaaag tgctttacta cttccgggta caaaaaacta tgttgaaaat tttagtgata
    33001 gaccgatgcc actttacccg tacgggcatg gaggcctggc ttaatcacac tgatgtgctc
    33061 agttcttcac tgctggtatc cgggatgaat aaccttatac tggcgaaaga acatattctg
    33121 caatggaagc cccatctggt tatcgctgat ttatatggtt ttctcaacga tgccttaccc
    33181 gagcagccta tcaatgcatt ttttgccgcc tgcaggatga cgccgttagt attattacag
    33241 tcagggaata tgccgtacag atcgcaatat gccagccatg cggtgttatc taaacacacg
    33301 cctttacatg agcttgcaca acgaattaaa ggagcgctat atactcatcc actgcaggaa
    33361 gcgccggaaa gcgccacgcc attgctctct ccgcaggagg aaaaagtgct cgcgatgtgg
    33421 acggaaggca ccagcaataa agagattgcg tatgcgcttg gcattcacgg aaaaacggtt
    33481 tacacctata agcgtaatat ccgtatgaaa cttcatatgg ataaccggta ttctcccttt
    33541 cttatgcttc cggagaaaat cgattaacgg tacgacgcca tgccgtaccg ttgatgatta
    33601 ctgctgagct ctggttgcag cgccagagat cgcactacca ccgtccgaga tgtcctcgcc
    33661 cacgccgcgc gtggtattac aagcagttaa tacagtggaa agtaccaaaa cagaaaagat
    33721 cgctgcaatt gtctttttaa ccataatgtc ttccttttct agccaatgtt gtttgtgtat
    33781 agcaacttaa taatagacaa catcccagaa aatgacgggc gatcgactaa ttttaggaag
    33841 acgagaagcg attagctggc tgcgcgggag atggcgtggc caagatgctg aatatcttcg
    33901 ccgaagccgc gggcggtatt acatgccgtt aataatgtgc cggtaagaag aaccagcgcg
    33961 acaaggccga taaagcgttt catcattgag gcgcgaaaaa taggatggcg cagcatacgc
    34021 tgcaccattt ttcccgataa cgtaaattat tttacgcggg atacgtattc gccggaacgg
    34081 gtatcgactt tgatcacttc gccaatctgc acgaacagcg gaactttaac cactgcgcca
    34141 gtagacagcg tggctggttt gccgccagta cctgcggtat cgcccttcag acctgggtcg
    34201 gtatcaacaa tttccagttc aacaaagttc ggcggagtga cagagatagg ctgaccgttc
    34261 cacagggtta cgatgcattc cgcctgatcc aacagccatt ttgcgttgtc gccaatagcc
    34321 ttggcatctg cagacagctg ttcgaaggtt tcgttgttca tgaaatgcca gaactcacca
    34381 tcgttgtaca ggtaagtcag gttcatatcg actacatccg cgccttcagc ggaatcggtc
    34441 gatttgaagg ttttctcaac gcgcgtgccg gtcagcagac ggcgcagctt aacgcgggca
    34501 aacgcctggc ctttacccgg tttcacgaat tcactggatt caaccgcata aggttcgcca
    34561 tccaacatga ttttaagacc ggaacgaaaa tcgttgctat agtaagtcgc cataaggccc
    34621 tctgaaattg ttaactggta gctaagccac aaaatggcgc atattgtaac cctaaatacc
    34681 ccattgcgag aagattggtt agcgcaactt gccgatgttg tgaccaatcc cgacgaactg
    34741 ctgcatcttt tacagattga agctgatgaa aacctccggg caagacagga cgccaggcgc
    34801 ttgtttgccc tccgcgtgcc gcgcgctttt attgcgcgca tggagaaggg caaccctgac
    34861 gatcctcttt tacgtcaagt gctgacgtcc cgggatgaat ttattgtcgc ccccggtttc
    34921 tccaccgacc cgctggaaga gcaacacagc gtggtgccag gattattgca taaataccaa
    34981 aaccgggcgc tattgctggt aaaaggcgga tgtgcggtaa attgccgcta ctgtttccgt
    35041 cgtcacttcc cgtatgcgga gaatcaaggc aataagcgca actggacagt cgcgctggag
    35101 tatatcgccg cacacccgga actggatgag atcatctttt ccggcggcga tccgctgatg
    35161 gcgaaagatc atgagctgga ctggctgctc acgcaactgg aagccattaa gcacgtcaag
    35221 cggctacgca tccacagtcg gttgcctatc gttatcccgg cacgcattac tgacgaactg
    35281 gtcgcccgct ttgaccagtc atgtctgcaa attttgttgg tgaaccatat caaccacgcc
    35341 aatgaagtgg acgaggcgtt ctgcctggcg atgaagaaac tgcgccacgt gggcgtcacg
    35401 cttctcaacc agagcgtcct gctgcgtggc gtgaatgata acgcgcaaac gctggcgaat
    35461 ctgagcaacg cgctatttga cgccggcgtg atgccctatt acctgcatgt gctggataaa
    35521 gtgcagggcg ccgcgcattt tatggtcacc gatgacgaag cccggcaaat catgcgcgaa
    35581 ctgctcacgc tggtatccgg ctatatggtg ccaagactgg cgcgtgaaat cggcggcgaa
    35641 ccgagcaaaa caccgctgga tttacagctt cggcagtgct aatcctcgcg ggcgcgtcag
    35701 ggacgacgaa aaatattacc gcgcaatatc acgaggagat tcccccgcga ttctcctcac
    35761 cctctggcga ggataaacta accttcgtta aatacacctt tccgatactc tcttttcaat
    35821 aaagtccgtt ttaggactcg cttagcgtgt actgcatttt cgaattatac tggttctcct
    35881 ttttatagga cggcataaac aatttatata tcaaatacat tgcagtaaaa catttaatta
    35941 ttttatattt gtggagaatt gacatggcct taacgattaa gggactaaat accggcgtta
    36001 ttcgtcacaa tgataagttt atcgcgctgg cgcttaaggt gaagtcactg agaaataaag
    36061 aaacactgct tttctttcct gtgctcgcgc tgcgagactt gttgatcggc cttgaacacc
    36121 ggctttattt acaatactcg cttccggaac aagagcagga aaaacgccag aaagccaaaa
    36181 gcagtcatgt gcttaaaatg catgagaata ttccggcaat actccgtgaa gagctggaaa
    36241 acgccgatgt taatcagcgt gttgaatctt tagcgttgag cgataataca gaaaaagtat
    36301 taacctttac gttaaagctg cacaatggta gccatcttga tttacaggtc ggtgagtggc
    36361 aggttgaagt tctggtgatg gctattattc acgccattaa taatgccgaa atgcgtgagc
    36421 tcgcattgcg tatttcttca atgctggact ttttaccatt atacgatgct gactgcctgg
    36481 ataacggtaa tatcgaattc gatacctata accagcctga ctggaaacat aatctgtata
    36541 accattattt agcgctcgtt tatcgttata cggatgaggc aggacaatcg catgattgcg
    36601 gcaccatcat taagacccgc agtcagtcag gctctaaaga agctgaagcg atatcacgcc
    36661 gcttgctgaa tttcagcccg cgtcttaaaa agctggaagg aaaaccgtgt aaggtttttg
    36721 tcagaacgct tggaaccggt aaagcagcgc gtctgacgca agatcaatgt atgcgcgcgt
    36781 tgcataatct acgcatggcg tcatcgcagg aaaaacgcta accatatcgc cctctgaatc
    36841 tttcagaggg cgttacgatt cagacatgtc aattcggaca tttataaacc tggccgttca
    36901 tctcgctggc cgtcgggaca aaactggaca acatgccctg cgacggacta cttacgccat
    36961 acagcacgtt tccacccatc gcggccgcct gattacgcag atcgttcgct gcgccacgca
    37021 ttgagccacc ctcttcgccg tgctggcctg aaaaccagtt actctgttta ccagttgccg
    37081 taccaataag ctggcattcc gcgcccggct tatcttcgac aaagcgtaca ttttggccgg
    37141 cagcggtgag ttcgttgctg gagctacaac ccgccatcag cagcgcggcg ccaacgatcc
    37201 ctgctaaata tttcacgtgc atgttattcc ccataatcaa tgagctggac gttttgtccg
    37261 tatctgaatc ttatactaaa aagatgacta aaagaaaaac ccccggtcat ttctgcccgg
    37321 gggtttctca attctgggag ataagcaccc aaatcattct ggttgcagga aggcggccag
    37381 tttgttaatc cccagtcact tactcaagta agtgactggg gttagccaac gcatctgcag
    37441 cctgaaggat gcagggggtg ggcaattaca tcatgccgcc cataccaccc ataccaccca
    37501 tgccgccagc agcgcctaaa tcaggagcat cgcttttcgg caggtcggtc accatgcact
    37561 cggtagtgat catcagacca gccacagaag ccgcgtattg cagcgcagaa cgggtaactt
    37621 tggttgggtc caagataccc atatcgatca tgttgccgta ttcttcagtt gctgcgttgt
    37681 aaccgtagtt accgtcgccg cctttaacgg tgttagcgac aacagacggc tcttcgccgc
    37741 agttcagcac gatctgacgc agcggagctt ccattgcgcg cagcgcaact ttgataccca
    37801 cgttctggtc ttcgttctgg cctttcaggt cagcaatttt agaagcaacg cggatcagcg
    37861 caacgccacc accagcaacc acgccttctt ctaccgcagc acgggtcgcg tgcagggcat
    37921 cttcaacgcg ggctttcttc tctttcattt caacttcggt cgcagcgcca actttgatta
    37981 ccgcaacgcc gcctgccagt ttcgctacgc gctcctgcag tttttcacga tcgtagtcgg
    38041 aggtcgcttc ttcaatctgc tgacggatct gagcaacacg gccctggatg gcagcttctt
    38101 cacccacgcc atcaatgatg gtggtggtgt ctttgttgat cacaacacgt ttcgcctgac
    38161 ccaggtcttc cagggttgct ttttccagct ccataccgat ctcttcagag attacggtac
    38221 cgccggtcag ggtagcgata tcctgcagca tcgccttacg acgatcgccg aagcccggtg
    38281 ctttaaccgc agccactttc acgatgccac gcatggtgtt cactaccagg gtagccagcg
    38341 cttcgccttc aacatcttca gcgatgatca gcagcggttt gcctgctttt gcaacggctt
    38401 ccagaaccgg cagcatttcg cggatgttgg agattttctt atcagccagc aggatgaacg
    38461 ggctttccag ttctactgcg ccagtttccg gcttgttgat gaaataagga gacaggtagc
    38521 cgcggtcaaa ctgcatacct tcaaccacgt ccagttcgtc ctgcagaccg gtaccgtctt
    38581 caacagtgat gacgccttct ttaccgactt tatccatcgc ttccgcgatc agtttaccta
    38641 cggtttcgtc ggagttagcg gaaatagtac ctacctgagc aatcgcttta gagtcggagc
    38701 acggtacgga cagcgccttc agctcttcaa ccgcagcagc aaccgctttg tcgataccac
    38761 gtttcaggtc catcgggttc atgcccgcag caacggcttt caggccttcg gtaatgatgg
    38821 actgcgccag tacggtcgcg gtggtggtgc cgtcgcctgc agcgtcgttc gctttagagg
    38881 caacttcttt caccatctgc gcgcccatgt tttcaaactt gtcttccagc tcgatttcac
    38941 gcgctacgga aacaccatct ttagtgatag tcggcgcacc gaaagattta tccagaacca
    39001 cgttacggcc tttcggaccg agggttactt tcactgcatc tgccagtacg tttacgccgc
    39061 gcagcatttt cacacgagcg tcgttaccga attttacgtc tttagctgcc attttctctt
    39121 tcccttaaat tcgtatgttc agtgtcgttc gcggattacg cttcaacaat tgccagaatg
    39181 tcgctttcag acatgatcaa cacttcttca ttgtcgatct tttcagattt cacaccgtag
    39241 ccatcgttaa aaataacgat gtcgccaact ttcacgtcca gcggctgtac agtaccgttg
    39301 tccaggatgc gacccttacc gacagcgatg atttcgccac gagttgattt acccgctgcg
    39361 gaaccggtca gtacgatgcc gccagcagat ttggactcaa cttctttacg tttgacgatc
    39421 acacgatcat gtaacggacg aatactcatt gatagctctc ctttgagaaa gtcattatca
    39481 gttatgggtg acgccggccc gtaaacggtt tcccggctgg tgaccagaga gatggggatg
    39541 gggttttgcc ccttcaaggg gggagatgaa aaaaaattct tctgagcgaa aaaagcggta
    39601 aaaacgctac ttatctcacg tttacccaag gtttagaaca tcctgctata agaaaaggcg
    39661 tgtgtgatac gcttaaaaat gtctgtcgtc acctgacgtt acaatgccgc cggataatga
    39721 gctgatgaat gaactaaaaa aagagcttgg gttggttcag ggcgttatct tgttaaccac
    39781 atcattatta gggactggcg tttttgcgct tccggagctg gctgcgctgg cggcaggcga
    39841 catcagcctt tgggcatggc cgctgctcat tattttgatt ttccctattg cgattgtctt
    39901 tgctgtgctg gggcgtcatt ttccacacgc tggcggcgta gcgcattttg tcgggatggc
    39961 atttggcccg cgtctgcaac gggtgatcag ttggctgttt ttatcagtca ttcctgttag
    40021 ttttcccgca gccttgcata ttgcggtggg tttcggccag gcgctgtttg gctggcaaag
    40081 cgaacagctc ttatttgggg agctgggtac tctaggtttg ctatggttta tgggatcgcg
    40141 cggcgccagc tccagcgcca acctgcaagc cattatcgct ggattaatta tcgcgcttat
    40201 tgccgccatt ctgtggaaag gcgcgattaa acctgcagat atcaccttcc cagccgcaaa
    40261 cgaaatcatc ttttcccggc tgtgtaccgc cctggcgatc atgttctggg gatttgtggg
    40321 aattgaggct tttacgcatt tgtcgtctga atttaaaaat cctgaacgtg attttccgcg
    40381 cgcattgatc attggcctga tgctggccgg cgccatttat tggacctgta ccgccgtggt
    40441 gctgcatttt ggcgtctata gcgacaagat agcggcaaca gcatcgctac cgcttattat
    40501 tgttcatctc ttcggtatcc aggcgttgtg gatagcctgc attattggtt atctcacctg
    40561 ctttgccagc ctgaatatgt atgctcagag ttttgcgcgt ctgatatgga cgcaaatgca
    40621 atatcagccc gatcactatc tggctcaact ctctcccggg cgccttccct tgcacgcgtt
    40681 aaacgttatt ctggcctgtt gttgcgtgag ttccctggtc gtctacgccc tgaagattaa
    40741 cctcaatgcg ctgatcgtct atgctaacgg tatttttatt atgctctatc tactttgtat
    40801 gctggcgggc tgtcgactgt tgaaagggcg ctgctatgca ctggcggtga cgggttgtct
    40861 actgtgcctg ttattgctag taatgctggg gtggaaaagc ttatatgcca ttattatgct
    40921 ggcagcatta tggctgtttt taccgaagcg aaaacgcatg gcgtaagacg tatctgttgg
    40981 ccggataacg cctcacgcga cttatccgac cagcatctct acctttaatc ccgacgatcg
    41041 tctttatgtt caatacgatc gcgatcgtca tctttacgct gatactcgcc gtcaaatgtt
    41101 tcgccaccgc cagtacccgc gctaaacccg ccgcccggca tccgggaaaa acgtaaatgc
    41161 ggcagcaact tcagcgtcaa atgtttttgc actggcggta acaaaaggag aaggccgaga
    41221 aaatcggtga aaaatcccgg caacaggagc agtaagccag cgatgatcag cgatacactc
    41281 ttaatcattt ctgccgccgg gctctcaccg gccgccattt tttgttgcat cagcaaaaag
    41341 tttttaaaac cctggttacg taccagcgac ataccgataa cagacgtaaa aatcaccagg
    41401 attagcgtca tcaggacgcc aagcacatgg gcgacctgga taaagataga aatctcaatg
    41461 taaacataga gaaagacagc taaaaagggt atccagcgca aaggactctc ctgtaagtca
    41521 tggccgtctg cgacgaccat ttaaatgggg ttgcgattcg catcgattcg atatggtggt
    41581 gcgtagcaaa atttcaagtg gtttgtacac ctattttagg tagtaatact aaagcggtga
    41641 cctatttcac aaaataataa ataaggggta aattcccaca ctttaagtga tccagattac
    41701 ggtaggaatt ctgaaccagc atatgatctc gtttatcagg ccgatggagg ggataatcgt
    41761 cggtcagaaa acattcgaaa tcacatatat cctgtgtgtt ttaaagtaaa aatcattggc
    41821 agcttgaaaa agaaggttca catgtcaaac aacattcgta tcgaagaaga tctgttgggt
    41881 accagggaag ttccagctga agcctactat ggtgttcaca ctctgagagc gattgaaaac
    41941 ttctacatta gcaataacaa aatcagcgac atccctgaat ttgtgcgtgg catggttatg
    42001 gtaaaaaaag cggcggcgct ggccaacaaa gagctgcaaa ccattcctaa gagtgtggcg
    42061 aatgccatca ttgccgcatg tgatgaagtc cttaacaacg gtaagtgcat ggaccagttc
    42121 ccggtagatg tctaccaggg cggcgcgggc acttccgtca acatgaatac caacgaagtg
    42181 ctggccaaca tcgggctgga actgatgggt catcagaaag gtgaatatca gtacctgaac
    42241 ccgaacgacc acgtgaataa atgtcaatcc actaacgacg cctatccgac aggcttccgt
    42301 gtagcggttt acgcctctat cgtcaaactg atcgatgcca tcaaccagtt gcgtgaaggt
    42361 ttcgaacgta aagcggttga attccaggac atcctgaaaa tgggtcgtac ccagttgcag
    42421 gacgccgtac cgatgacgct tggtcaagaa ttccgtgcgt tcagcattct gctgaaagaa
    42481 gaagtgaaaa gcatcgagcg tactgctgag ctgctgctgg aagtcaacct tggcgcaacg
    42541 gcaatcggta ctggtctgaa cacgccgaaa gaatactctc cgctggcggt gaaaaaactg
    42601 gctgaagtca ctggtttcgc ctgtgttccg gctgaagatc tgattgaggc gacatctgac
    42661 tgtggcgcgt atgttatggt tcacagcgcg ctgaaacgtc tggcagtgaa gatgtccaaa
    42721 atctgtaacg acctgcgctt gctctcttct ggtcctcgtg ccggcctgaa cgagatcaac
    42781 ctgccggaac tgcaggcggg ctcttccatc atgccagcca aagtgaaccc ggtagtaccg
    42841 gaagtcgtaa accaggtatg ctttaaagtc atcggtaacg acaccaccgt tacgatggcg
    42901 gcggaagccg gtcagttgca gttgaacgtt atggagccgg ttatcggtca ggcgatgttc
    42961 gaatccatcc acattctgag caacgcgtgc tacaacctgc tggaaaaatg cgttaacggc
    43021 attaccgcga ataaagaagt gtgcgaaggg tacgtttata actccatcgg tatcgtcact
    43081 tacctcaacc cgttcatcgg ccaccacaac ggcgacatcg tcggtaaaat ctgtgctgaa
    43141 accggtaaga gcgtacgtga agttgtgcta gagcgcggcc tgttaacgga agccgagctg
    43201 gacgatattt tctccgtaca gaacttgatg cacccggctt ataaagctaa acgttatact
    43261 gatgaaagcg aacagtaatc gtacagggta gtaccaaaga ggcacgtcac gatgacgtgc
    43321 cttttttctt acaagaagtt accaaataac aacaatttaa tatcaacttg ttaaacaaca
    43381 aggaaggcta atatgatagt tgtcgaactt atcattgttt tgctggcaat ctttttgggc
    43441 gccagacttg ggggcatcgg tattggattc gcaggtgggc tgggtgttct ggtacttgcc
    43501 gccatcggcg tgaagccagg gacaattcca ttcgatgtca tttccatcat catggcggtt
    43561 atcgccgcga tctctgctat gcaggtcgcg ggcggtctgg attatttggt aaaccagaca
    43621 gaaaaactgc tgcgtaagaa cccgaaatac atcactatcc tcgcaccgat tgtgacctat
    43681 ttcctgacta tttttgctgg taccgggaac atttccctgg caacgctgcc ggttattgct
    43741 gaagtcgcga aggagcaggg aatcaaacct tgccgtccgc tctcaaccgc cgtggtatcc
    43801 gcgcagattg cgattaccgc ctcgccgatt tctgcggctg tggtgtatat gtcttctgtt
    43861 atggaaggtc atggcattag ctacattcac ctgctgtccg tggttatccc ctctacgctg
    43921 ctggcggtgc tggtgatgtc cttcctggtc acgatgctgt tcaactccaa actgtcggac
    43981 gacccgattt accgcaagcg tctggaagaa gggctgattg aactgcgtgg tgaaaagcag
    44041 attgaaatca aaccgatggc aaaaaattcc gtctggctgt tcctgctggg cgttatctgc
    44101 gtggttgttt atgcgattgt caacagtccg agcctcggcc tggttgagaa accgctgatg
    44161 aacaccacca acgctatttt gatcatcatg ttgagcgtcg caacgctgac caccatcctg
    44221 tgtaaagtgg aaactgacgc catcctcaac tccagtacct ttaaagcagg gatgagcgcc
    44281 tgtatttgta ttctgggcgt ggcgtggctg ggcgatacct tcgtatccgc taacatcgac
    44341 tggatcaaag acactgcggg tagcgtcatc caggggcatc cgtggctgct ggccgtcatc
    44401 ttcttctttg cttccgcgct gctctactct caggcggcaa cggcgaaagc gctgatgccg
    44461 atggcgctgg cgctgaacgt ctctccgctg acggcagtcg cttccttcgc cgccgtttcc
    44521 ggcctgttca ttttgccgac ctacccgact ctggttgcgg cggtacagat ggatgacacc
    44581 ggtacaaccc gtatcggtaa attcgtcttt aaccacccgt tcttcatccc aggcaccctg
    44641 ggcgtcgttc tggctatctg ctccggcttc ctgctgggca gctttatgct gtaagtgttt
    44701 cacccgcggg gcgtatcacg ccccgcattc tcccgccctt tgactaacat cctgccctcg
    44761 tccgttgtat agtgaccgtt cacttgcggg tctttttgtt ctttcgaggt gtttatgctt
    44821 gatgttaaga gtcaggatat ttccatcccc gaggctgttg tggtgctttg taccgccccg
    44881 gatgaagcta ccgcccagga tctggccgcc aaagtgctgg cggaaaaact ggccgcctgc
    44941 gccaccctcc tccccggcgc gacatcgctg tactactggg aaggcaaact ggagcaggag
    45001 tatgaagttc aaatgatctt aaaaaccacc gtttcacatc agcaagcgct tatcgactgc
    45061 ctgaagtctc atcacccgta tcaaacgcct gaacttctgg ttttacctgt tactcacgga
    45121 gatactgatt acctctcatg gctcaacgca tctttacgct gatcctgctg ctgtgcagca
    45181 catccgcctt cgccggatta ttcgacgcgc cgggtcgctc gcagttcgtc cctgccgacc
    45241 gggcgtttgt ttttgatttt cagcaaaatc aacacgatct taccctctcc tggcaggtaa
    45301 aagagggtta ctacctttac cgtaaacaaa tcagtatcac gccgacgaaa gcggatatcg
    45361 ccgcagtcca actcccggca ggcgtctggc atgaagatga attctacgga aaaagcgaaa
    45421 tctaccgtaa gcggctaaac gttccggtaa cggttaacca ggcggcggct ggcgcgacat
    45481 taacgataac gtaccagggg tgcgccgatg cgggattctg ttatccgccg gaaacgaaaa
    45541 cggtgccgct aagtgaagtc gccgcggcaa tagacgccac gccgacgcct gctgtcaccc
    45601 agacgggtga gacgtcaaaa cccgccgccc agctaccttt ttctgcgctc tgggcgctac
    45661 tgatcggcat aggcatcgcc tttacgccct gcgttttacc tatgtatccg ctgatttccg
    45721 gtattgtcct ggggggaagg caacgtttgt cgacggggcg cgcactgctg ctggccttta
    45781 tctatgtaca agggatggcg ctgacctata ccgcactggg tctggtcgtc gccgcggcgg
    45841 gattacagtt tcaggcggcg ctgcagcacc cttatgtgtt aatcggcctt gccatcgtgt
    45901 tcaccctgct tgcgttgtcg atgtttggcc tgttcacact acagctcccc tcctcactgc
    45961 aaacccggct gacattaatg agtaatcgtc agcaaggcgg ctcgcccggc ggtgtttttg
    46021 ttatgggggc gattgcagga ttaatttgct cgccctgtac cacagcgcca ttaagcgcga
    46081 tcctgcttta tatcgctcag agcggcaaca tgtggctggg cggcggtacg ctgtatttgt
    46141 atgcattagg tatgggtctg ccgctaatgc tggtcaccgt gtttggcaac cgtctgctac
    46201 cgaaaagcgg cccgtggatg gcgcatgtta aaaccgcttt tggtttcgtg atcctcgcgt
    46261 taccggtctt tttactggag cggattattg gcgaggcttg gggtttacgt ctgtggtcgc
    46321 tgctgggcgt cgctttcttt ggttgggcct ttatcaccag ccttcaggcc agacgagcgt
    46381 ggatgcgtat cgtacagatt atcctgctgg cggcagcgct cattagcgtg cggcctctac
    46441 aagattgggc attcggatcg ccatccgcgc aagctccagc gcacctcaat ttcacggcta
    46501 tttctaccgt ggatgaactc aatcaggcgc tggcgcaggc caaaggcaaa cccgttatgc
    46561 tggatttcta cgccgactgg tgcgtggcct gtaaagagtt tgaaaagtat accttcagcg
    46621 atccgagggt ccagcaggtg ctcggcgaca cggtgctctt gcaggctaac gtcaccgcta
    46681 acaatgcgca ggacgtcgcg ctgttaaagc atctgcaagt tctcgggctg cccaccattc
    46741 tgttctttga tgcccaaggc caggaacagc cgcaagcgcg agtcaccggc tttatggacg
    46801 ccgccacctt tagcgcgcat ttgcacgatc gccaaccatg agcgacactt gcaaaagcaa
    46861 agacggagga gaataccgtg caacgtgaag atattctggg agaagccctg aaattactgg
    46921 agacgcaagg gatagccgat actacgctgg aaatggtggc ggagcgcgta aatcgcccac
    46981 tcgacacatt acagcgtttc tggccagata aagaagccat tttatatgac gcgctacgtt
    47041 atctgagtca gcaggtagat atctggcgac gccagcttct tcttgatgag acgttttctg
    47101 ctgaacaaaa gctactggca cgctacagcg cgctttcgga atgtgtcagt aataaccgtt
    47161 atcctggttg cttgttcatt gccgcctgta cgttttatcc cgacccaacc catcctattc
    47221 accaactggc taatcaacaa aaacgcgcgg cacatgattt tacccatggg ctactgacca
    47281 cgctggaaat tgacgatccg gcgatggttg caaggcagat ggaactggtg ctggaaggtt
    47341 gtctcagccg aatgctggtc aaccgcagtc aggctgatgt agataccgct cagcggttgg
    47401 cggaagatat tctgcgtttt gcacagtgcc gtcagggtgg agcgctcacc tgacgggtac
    47461 tgattttatg cattttgcct gaaaagcagg cagtcagcgc gcttttatca cttttttcgt
    47521 gtaaagccgt tgacgaccgc gcccctttac ggtttaatgc gccccgttgc ccggatagct
    47581 cagtcggtag agcaggggat tgaaaatccc cgtgtccttg gttcgattcc gagtccgggc
    47641 accacctttc cttttttatg cttccctatg aattccaata tgtatgtaat tcaataagtt
    47701 agcgtaaaaa tctttccaga tgcgttttga tttatcccta cgtatccgga aaattagggg
    47761 tcaggttgag ggttcattca gttcgatgaa cggagaggcc ctcatgttga ctgacagcaa
    47821 gatccgcgcc gcgaaacccc tcgcaaaatc ctataaactc actgatgcac aaggtctgta
    47881 cctgacggta tccaccagtg gttcaaagct atggtatttc cgctaccgtt ttgaaggtaa
    47941 ggaaaatcgt ctggccttcg gcccctatcc gcaggttacg ctggcggaag cccgcgaaaa
    48001 gcgcgatgcg gcgcgtaagc tgctggtatc cggcgtttgc ccttctctgc cccgcaaggc
    48061 ggaaaaagcc gccgttgacg gtacgcgcac ctttcagtac atcgccacgg cgtggcactc
    48121 cagttgtctt aagctgtggt cagaagacca cgcggacaag atcctgacct gcctgaagcg
    48181 ctacgtcttc cccgatattg gcgcaatgga cattgcagag gttgaaaccc gccatctggc
    48241 gcagcttgtt aaatccatcg acgataaggg cgtgcatgac gttgccgggc gggtgcgcca
    48301 gcatctgacc aaaatcatgc gtcatgccgt acagcaggga acgattaaat ataatccggc
    48361 ttacgatctg gatggcgtcg tgacccctgt tgtgacccaa catcaccccg ccctgcccct
    48421 gaaacgcctg ccggagctgc tggacaagat taatggctac aaagggcggg aactgacccg
    48481 tctggcgctg gagttgaatc tgcacgtttt cctgcgctcc agtgagttac gcctcgcccg
    48541 ctgggatgag ttcaacctga aagctcgtat ctggacggtg ccagcaaagc gggaagcggt
    48601 gaagaacgtg cgtttctcag agcgtggcgc aaagatgaag gatgagcatc tggtgccgct
    48661 atctgcgcag gctgtcgccc tgctggagca gataaaggaa attaccggag agtcggtatt
    48721 tgtttttgcg ggtgctcact caatgaacaa gccgatgagt gaaaacacca tcaacaaggc
    48781 gctgcgcgtg attggttacg acaccaaaac cgaagtctgc ggtcacggat tcagaacgat
    48841 ggcctgtagc gccctgaacg aatccgcact gtggtctaag gacgccatcg agcgccagat
    48901 gagccacaag gagcgcaacg gcgtgcgggc ggcgtatgtg cataaggcgg agcatctgga
    48961 agcgcgtatg gagatgatgc agtggtggtc ggattatctc gacatgagcc gcgaggggta
    49021 cgtcgcgccg tatatttatg cgcggcggca taaggctgcc tgacccagcg gcaatataat
    49081 ttgttgataa tgaaaaagca gatcctgatt gaatccggat ctgctttttg tattgaaagg
    49141 atttaacttc aattttttga ttgttaatag gaaagcctac aaaaatattc tacgtagaat
    49201 atttttgtac ga
//
LOCUS       DAJVKX010000021        46216 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000021 DAJVKX010000000
VERSION     DAJVKX010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 46216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46216
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.021"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            170..1959
                     /locus_tag="OPY25_001149"
                     /pseudo
     CDS             170..1959
                     /locus_tag="OPY25_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462979.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
     gene            2160..2822
                     /locus_tag="OPY25_001150"
     CDS             2160..2822
                     /locus_tag="OPY25_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02117 family protein"
                     /protein_id="HCS0926807.1"
                     /translation="MKNLFIAWLSLLLYGCTTFPQAVKPTTGGQPSPTEIYIVSHGWH
                     TGIIAPAHDVNTVLPQLKKRFAQETQWYEIGWGDKGFYQSQEITTALTLQAMFWSSGA
                     VMHIVAFSGQPERYFAGSEIKSLLLHTNQRNSLMRYLGRSFARDAEGNLIPLKQGIYG
                     DSQFYAANGRYGILNTCNKWTAKGLESAGLTINPSLKLTAGSVMKAITDHRMCLNKYC
                     YP"
     gene            complement(2868..3080)
                     /gene="rpmE"
                     /locus_tag="OPY25_001151"
     CDS             complement(2868..3080)
                     /gene="rpmE"
                     /locus_tag="OPY25_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HCS0926808.1"
                     /translation="MKKGIHPNYVEITATCSCGNVIKTHSTVGHDLNLDVCGKCHPFF
                     TGKQRVVDTGGRVERFNKRFSIPGSK"
     gene            3284..5482
                     /gene="priA"
                     /locus_tag="OPY25_001152"
     CDS             3284..5482
                     /gene="priA"
                     /locus_tag="OPY25_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCS0926809.1"
                     /translation="MSVAHVALPVPLPRTFDYLLPEGGVAKAGCRVRVPFGKQQERVG
                     IVVSVSDHSELPLDELKSVIEILDNEPIFSPSIWRLLLWAADYYHHPLGDVLFHALPV
                     LLRQGKPASNAPLWYWFATEEGQAVDINSLKRSAKQQQALAALRQGKIWRYQVAELDF
                     TDATLQTLRRKGLCELASETPAFTDWREHYAVAGERLRLNTEQATAVGAIHSASDGFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNTPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSSLFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVRQKKYRMLRLTRRAGNARPALQHVL
                     DLKGQRLQAGLAPALIARMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHMLPVGLGTEQLEQVLAPFFPGVPIS
                     RIDRDTTSRKGALEQHLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVSGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RQTLQLPPWTSHVIIRAEDHNNQQAPVFLQQLRNVIQASPLSDDKLWILGPVPALAPK
                     RGGRYRWQILLQHPSRILLQHIISGTLALINTLPEARKVKWVLDVDPIEG"
     gene            5637..6662
                     /gene="cytR"
                     /locus_tag="OPY25_001153"
     CDS             5637..6662
                     /gene="cytR"
                     /locus_tag="OPY25_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HCS0926810.1"
                     /translation="MKSNKQVTAATMKDVALKAKVSTATVSRALMNPDKVSQSTRSRV
                     EQAALEVGYFPQSMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAAEQGYLVLI
                     GDCAHQNQKEKTFLNLIITKQIDGMVLLSSRLPFDASVEEQRNLPPMVMSNEFAPELE
                     LPTVHIDNLTAAFNAMNYLLDLGHKRIGCIAGPEDMPLCHYRLQGYVQALRRSGIVVD
                     PHYIARGDFTFEAGANALKQLLEQPLPPTAVFCHSDVMALGALSWAKRQGLKVPDDLS
                     IIGFDNIALAEFCDPPLTTVAQPRFDIGREAMLLLLDQMQGQNVSSGSRLMDCELIIR
                     GSTRALP"
     gene            6756..7739
                     /gene="ftsN"
                     /locus_tag="OPY25_001154"
     CDS             6756..7739
                     /gene="ftsN"
                     /locus_tag="OPY25_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HCS0926811.1"
                     /translation="MAQRDYVRRGQPAPSRRKKSTSRNSRKKQSNMPAVSPAMVAIAA
                     AVLVTFIGGLYFITHHKKEESETLQNQKVTGNGLPPKPEERWRYIKELESRQPGVRTP
                     TEPSAGGEVMNPNQLTSEQRQLLEQMQADMRQQPTQLNEVPWNEQTPEQRQQTLQRQR
                     QAQQQQQQQWAQTQPVQQPRTQPRVNEQPQTRTVQSAPAQPARQSQPPKQTASQQPYQ
                     DLLQTPAHTSAAAPKAAPITRAPEAPKATAEKKDERRWMVQCGSFKGAEQAESVRAQL
                     AFEGFDSKITTNNGWNRVVIGPVKGKENADSTINRLKMAGHTNCIRLATGG"
     gene            7831..8361
                     /gene="hslV"
                     /locus_tag="OPY25_001155"
     CDS             7831..8361
                     /gene="hslV"
                     /locus_tag="OPY25_001155"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HCS0926812.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELGAREIAEKALDIAGDIC
                     IYTNHFHTIEELTAKA"
     gene            8371..9702
                     /gene="hslU"
                     /locus_tag="OPY25_001156"
     CDS             8371..9702
                     /gene="hslU"
                     /locus_tag="OPY25_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HCS0926813.1"
                     /translation="MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFR
                     KKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSIFQNLGGQKQKPRKLKI
                     KDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGA
                     RRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL"
     gene            9769..10698
                     /gene="menA"
                     /locus_tag="OPY25_001157"
     CDS             9769..10698
                     /gene="menA"
                     /locus_tag="OPY25_001157"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCS0926814.1"
                     /translation="MTEQQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGYFDP
                     LVALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALII
                     TVVLICISGLALVAVACHTLTDFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVL
                     VFFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLV
                     VRLGDVNARRYHACLLLGALLCLALFNLLSLHSPWGWLFILAAPLLIKQARYVMRERE
                     PAAMRPMLERTVKGALLTNLLFVIGILLSQWAV"
     gene            10791..11276
                     /gene="rraA"
                     /locus_tag="OPY25_001158"
     CDS             10791..11276
                     /gene="rraA"
                     /locus_tag="OPY25_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HCS0926815.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRSSFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLLVDGGGSVRRALVDAELARLATQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAIAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(11498..11737)
                     /gene="zapB"
                     /locus_tag="OPY25_001159"
     CDS             complement(11498..11737)
                     /gene="zapB"
                     /locus_tag="OPY25_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HCS0926816.1"
                     /translation="MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLTQEVQSA
                     QHQREELERENNFLKEQQSGWQERLQALLGRMEEV"
     gene            12136..12981
                     /locus_tag="OPY25_001160"
     CDS             12136..12981
                     /locus_tag="OPY25_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HCS0926817.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGATFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVVPFIISQVAGAFCAAA
                     LVYGLYYNLFVDFEQTHHIVRGSVESLDLAGIFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKMFAGLAG
                     WGEIAFTGGRDIPYFLVPLFGPIVGAILGAFAYRKFIGRHLPCDICVVEEKDSTAATQ
                     QNASL"
     gene            13002..14507
                     /gene="glpK"
                     /locus_tag="OPY25_001161"
     CDS             13002..14507
                     /gene="glpK"
                     /locus_tag="OPY25_001161"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCS0926818.1"
                     /translation="MTEKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGW
                     VEHDPMEIWASQSSTLVEVLAKADISSDQIAAIGITNQRETAIVWERETGKPIYNAIV
                     WQCRRTANICEQLKRDGLEDYIRDNTGLVVDPYFSGTKVKWILDHVEGSRERAKRGEL
                     LFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHDLDWDDKMLDVLDIPRAMLPQVR
                     KSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTG
                     EKAVKSENGLLTTIACGPSGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFAT
                     KVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAYQTRDVL
                     EAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLA
                     VGYWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRAMAWEEHDK"
     gene            14619..15629
                     /gene="glpX"
                     /locus_tag="OPY25_001162"
     CDS             14619..15629
                     /gene="glpX"
                     /locus_tag="OPY25_001162"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HCS0926819.1"
                     /translation="MRRELAIEFSRVTEAAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGHGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGAIDLNLPLADNLRNIADALGKPLGDLTVT
                     ILAKPRHDEVIAEMAKLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMQGRLLARHDVKGDSEENRRIGEQELARCKAMGIEAGKALCLGDMARSD
                     NVIFSATGITKGDLLEGISRKGHIATTETLLIRGKSRTIRRIQSIHYLDRKDPDVQAH
                     IL"
     gene            15726..16472
                     /gene="fpr"
                     /locus_tag="OPY25_001163"
     CDS             15726..16472
                     /gene="fpr"
                     /locus_tag="OPY25_001163"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HCS0926820.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPINPFTAGQFTKLGLEID
                     GERVQRAYSYVNAPDNPNLEFYLVTVPQGKLSPRLAALKPGDEVQVVSDASGFFVLDE
                     VPDCETLWMLATGTAIGPYLSILQYGQDVTRFKNLVLVHAARFAADLSYLPLMLELQQ
                     RYEGKLRIQTVVSRESVPGSLTGRVPALIENGELEKAVGLPMDKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(16579..17007)
                     /locus_tag="OPY25_001164"
     CDS             complement(16579..17007)
                     /locus_tag="OPY25_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HCS0926821.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLALFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVMVKRLHDRGRSGAWALLMILAWMLLAGNWVMLPGMWQWVVG
                     RFIPTLILVMMLIDLGAFVGVQGENKFGKATQDVKFKAEP"
     gene            17108..17704
                     /locus_tag="OPY25_001165"
     CDS             17108..17704
                     /locus_tag="OPY25_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HCS0926822.1"
                     /translation="MKPGCTLFLLLFSALTASITAHAQLSSSTTTAPYLLAGSPTFDL
                     SISQFRENFNRQNPDLPLNEFRAIENSRDKANLTRAASKINENLYASTALERGTLKVK
                     SMQITWLPIQGPEQKAAKAKALEYMAAIIRTVAPLLTKEQSQKKLQKMLIAGKGKHYY
                     AETEGAVRYVVADNGEKGLTFAVEPIKLALSENLEGAN"
     gene            17817..18584
                     /gene="tpiA"
                     /locus_tag="OPY25_001166"
     CDS             17817..18584
                     /gene="tpiA"
                     /locus_tag="OPY25_001166"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCS0926823.1"
                     /translation="MRHPLVMGNWKLNGSRHMVNELVANLRKELTGVAGCDVAIAPPE
                     MYIDLAKRAAAGSHIMLGAQNVDLNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDTVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKADAKIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(18676..19440)
                     /locus_tag="OPY25_001167"
     CDS             complement(18676..19440)
                     /locus_tag="OPY25_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCS0926824.1"
                     /translation="MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEAL
                     NQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDVHLMVADQWAAAQACVKAGAHCI
                     TLQAEGDIHLHHTLSWLGQQTVPVIDGEMPVIRGISLCPATPLDVIIPILSDVEVIQL
                     LAVNPGYGSKMRSSDLYERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRV
                     VSGSALFRDDRLVENTRSWRAMFKVAGDTTFLPSTA"
     gene            complement(19450..19740)
                     /gene="lsrG"
                     /locus_tag="OPY25_001168"
     CDS             complement(19450..19740)
                     /gene="lsrG"
                     /locus_tag="OPY25_001168"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HCS0926825.1"
                     /translation="MHVTLVEINVHDDKVEQFIDVFRQNHLGSIKEPGNLRFDVLQDP
                     QVPTRFYIYEAYVDEQAVAFHKTTPHYKTCVEQLEPLMTGPRTKKVFMGLMP"
     gene            complement(19823..20698)
                     /gene="lsrF"
                     /locus_tag="OPY25_001169"
     CDS             complement(19823..20698)
                     /gene="lsrF"
                     /locus_tag="OPY25_001169"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HCS0926826.1"
                     /translation="MADLDDIKDGKDFHTDKPQTNTLFSLKGCGALDWGMQSRLARIF
                     NPRTRKTVMLAFDHGYFQGPTTGLERIDINIAPLFEYADVLMCTRGILRSVVPPAINK
                     PVVLRASGANSILTELSNEAVAVAMDDAVRLNSCAAAAQVYIGSEHEHQSIKNIIQLI
                     DAGLRVGMPIMAVTGVGKDMARDQRYFSLATRIAAEMGAQIIKTYYVDKGFERIAAGC
                     PVPIVIAGGKKLPEREALEMCYQAIDQGASGVDMGRNIFQSEDPVAMIKAVHAVVHHN
                     ETAERAYELFLSEKG"
     gene            complement(20727..21749)
                     /gene="lsrB"
                     /locus_tag="OPY25_001170"
     CDS             complement(20727..21749)
                     /gene="lsrB"
                     /locus_tag="OPY25_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HCS0926827.1"
                     /translation="MARHSIKMIALLTAFGLASAVMTVQAAERIAFIPKLVGVGFFTS
                     GGNGAQEAGKALGIDVTYDGPTEPSVSGQVQLVNNFVNQGYDAIIVSAVSPDGLCPAL
                     KRAMQRGVKILTWDSDTKPECRSYYINQGTPKQLGSMLVEMAAHQVDKEKAKVAFFYS
                     SPTVTDQNQWVKEAKAKISQEHPGWEIVTTQFGYNDATKSLQTAEGIIKAYPDLDAII
                     APDANALPAAAQAAENLKRNNLAIVGFSTPNVMRPYVQRGTVKEFGLWDVVQQGKISV
                     YVANALLKNMPMNVGDSLDIPGIGKVTVSPNSEQGYHYEAKGNGIVLLPERVIFNKDN
                     IDKYDF"
     gene            complement(21778..22779)
                     /gene="lsrD"
                     /locus_tag="OPY25_001171"
     CDS             complement(21778..22779)
                     /gene="lsrD"
                     /locus_tag="OPY25_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
                     /protein_id="HCS0926828.1"
                     /translation="MMNPWRRYSWEIALAALLIFEILAFGLINPRLLDINVLLFSTSD
                     FICIGIVALPLTMVIVSGGMDISFGSTIGLCAITLGVLFQLGMPLPLAIIITLLLGAI
                     CGLINAGLIIYTGVNPLVITLGTMYLFGGSALLLSGMAGATGYEGIGGFPTAFTDFAN
                     ISFLGIPMPLIFFLVCCLFFWLLMHRTHMGRNVFLIGQSARVAQYSAIPVNRTLYTVY
                     AMTGCASAIAAVLLVSYFGSARSDLGASFLMPTITAVVLGGANIYGGSGSIMGSALAA
                     LLVGFLQQGLQMAGVPNQISSALSGALLIVVVVGRSVSLHRHQILEWYSRRRNAHQA"
     gene            complement(22776..23819)
                     /gene="lsrC"
                     /locus_tag="OPY25_001172"
     CDS             complement(22776..23819)
                     /gene="lsrC"
                     /locus_tag="OPY25_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HCS0926829.1"
                     /translation="MLKFIQNNREATALLAIVCLFVFLGALDSQYLSVQTLTMVFSSA
                     QILMLLAIGATMVMLTRNIDVSVGSTTGMCAVLLGVMLNAGYSLPVACLATLILGIVA
                     GFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAGLKQLSAPVFLGIS
                     AIGWFTLVLALLMAWLLAKTAFGRNFYATGDNLQGARQLGVRTEMVRIMAFSLNGGMA
                     ALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGTVIGAILGAYFLTQID
                     SVLVLLRIPAWWNDFIAGLVLLGVLVFDGRLRCALQRNLRRQKYARFISPPTPLQAEA
                     KTHAQQNKNKEVA"
     gene            complement(23813..25348)
                     /gene="lsrA"
                     /locus_tag="OPY25_001173"
     CDS             complement(23813..25348)
                     /gene="lsrA"
                     /locus_tag="OPY25_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HCS0926830.1"
                     /translation="MQISHNTASPLICVQNIYKSYSGVEVLKGIDFTLHAGEVHALLG
                     GNGAGKSTLMKIIAGIVPPDGGTIDIAGVRCSHLTPLKAHQYGIYLVPQEPLLFPSLS
                     VRENILFGLQGRQASTEKMQQLLKAMGCQLDPASAAGTLDVADRQIVEIMRGLMRDSR
                     ILILDEPTASLTPAETDRLFTRLQELLKKGVGIVFISHKLPEIRQLAHCVSVMRDGKI
                     ALFRKTHDLSTDEIIQAITPATQGVSLSASQKLWLELPGSRPQNERGATVLALESLTG
                     EGFMNINLEVRAGEILGLAGLVGAGRTELAETLYGIRPVNAGRMLFNGEEINALTTQQ
                     RLQLGLVYLPEDRQSSGLYLDASLAWNVCSLTHNQKGFWIKPQRDNATLERYHRALNI
                     KLNNAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARSDIYQLLRSIA
                     QQNVAVLFISSDLEEIEQMADRVYVMHQGELGGPALCGEEINVDTIMHVAFGEHGASE
                     ATC"
     gene            25604..26563
                     /gene="lsrR"
                     /locus_tag="OPY25_001174"
     CDS             25604..26563
                     /gene="lsrR"
                     /locus_tag="OPY25_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HCS0926831.1"
                     /translation="MSDNTLVSDYGMCEEEQVARIAWFYYHDGLTQSEISERLGLTRL
                     KVSRLLEKGHQSGIIRVQINSRFEGCLEYENALRNHFALQNIRVLPALPDADIGLRLG
                     IGAAHMLMESLRPQQLLAVGFGEATMTTLKRLSGFISAQQIRLVTLSGGVGPYMTGIG
                     QLDAACSVSIMPAPLRASSQEIACTLRNENSVRDVMLTAQAADAAIVGIGAINQKDQA
                     SILKSGYITQGEQLMIGRKGAVGDILGYFFDAHGEIIPDIKIHNELIGLKLNSLSTIP
                     TVIGVAGGEQKAEAIIAAMRGNYINALVTDQKTAGKIIQLIEK"
     gene            26650..28242
                     /gene="lsrK"
                     /locus_tag="OPY25_001175"
     CDS             26650..28242
                     /gene="lsrK"
                     /locus_tag="OPY25_001175"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HCS0926832.1"
                     /translation="MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQ
                     HLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSN
                     GEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPD
                     IYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDIL
                     SPVKETGTLLGHISQKAAEQCDLQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDAYSLLEDMASRVPPGAHGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKAT
                     LFRALEENAAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVP
                     VVKEATALGCAIAAGVGVGIWPSLAETGEKLVRWDREHKPNPENFAVYQQAREKWQAV
                     YQDQRALVDGGLTTSLWKAPGL"
     gene            28256..28537
                     /locus_tag="OPY25_001176"
     CDS             28256..28537
                     /locus_tag="OPY25_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCS0926833.1"
                     /translation="MQKTNEKNHEYRFSDNGPKYLIRGPGCDMGVVILQPGQSFPNHR
                     HNTACEVFYTLSGEVCLYLEGTPHILQTGDVLQCEPGEAHYLINNGDKP"
     gene            complement(28696..28836)
                     /locus_tag="OPY25_001177"
                     /pseudo
     CDS             complement(28696..28836)
                     /locus_tag="OPY25_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
     gene            complement(28843..29013)
                     /locus_tag="OPY25_001178"
     CDS             complement(28843..29013)
                     /locus_tag="OPY25_001178"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926834.1"
                     /translation="MSLWLSYPLILPSIIVGITILLWATSLLPEFMTALLFFAAVVAM
                     GPGKVPARAGMQ"
     gene            complement(29111..29833)
                     /locus_tag="OPY25_001179"
     CDS             complement(29111..29833)
                     /locus_tag="OPY25_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0926835.1"
                     /translation="MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSY
                     NVSLIVVKQAWSELINAGIISSQRGSGSVVCSVPEGVSYGHTFRGITRDLQDASVAIE
                     NRILEIAPRRARDAQADGLSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPDLQL
                     TPQALEHTSLYSLLNVTSDSAIEKVEAILPSADLCEKLQIAPNKPLLSVARQTFQAGK
                     DSPFEYCRYYVLSEYFGEIHYH"
     gene            complement(29896..30936)
                     /locus_tag="OPY25_001180"
     CDS             complement(29896..30936)
                     /locus_tag="OPY25_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCS0926836.1"
                     /translation="MHVDQNKILGCLVGAAAADAMGAATEVRTQQQIKDYFGGWVTTF
                     QKPPADTFGRCNEAGMCTDDFIQAKYIMDALLRHQREVSDEAMREAFQQWLDYPYYAN
                     FTGPTTRAAMKAIFNDNRASLQGELEGEKQSVQIINKGNAEATNGAAMKIWPAAVLHP
                     GDIDAAIDCALQICRFTHNNVLAMSGAAAMAAATSEALRAQTNADSIIAAGIYGAQRG
                     YLLAQEQGAMMVAGPSVARRIELAVDIGKRHRHWETAIVDIADIIGSGLHVSEAVPAA
                     FGLFACCPNSAVDAIISGVNIGNDTDTVATMVGAISGAFHGVEAFPADYLTTLDRMNH
                     FDLAELARQIAG"
     gene            complement(30946..31905)
                     /locus_tag="OPY25_001181"
     CDS             complement(30946..31905)
                     /locus_tag="OPY25_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HCS0926837.1"
                     /translation="MKAMNKVWVIGDASVDLVPEKQNSYLKCPGGASANVGVCVARLG
                     GECGFIGCLGDDDAGRFLRQVFQDNGVDVSSLRLDAALTSAVLIVNLTADGERSFTYL
                     VHPGADTYVSPQDLPPFRQHEWFYFSSIGLTDSPAREACLEGARRMREAGGYVLFDVN
                     LRSKMWRNTDEIPELIARSAALASICKVSADELCQLSGASHWQDARYYLRDLGCDTTI
                     ISLGADGALLITAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEA
                     ISNANACGAMAVTAKGAMTALPFPDQLNTFLSSHSLAQAMTVK"
     gene            complement(31916..33250)
                     /locus_tag="OPY25_001182"
                     /pseudo
     CDS             complement(31916..33250)
                     /locus_tag="OPY25_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462946.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(33516..34271)
                     /locus_tag="OPY25_001183"
     CDS             complement(33516..34271)
                     /locus_tag="OPY25_001183"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HCS0926838.1"
                     /translation="MKKTGYFLLAVIVIVAAAGVGYWKFSGNPDALREIVLERCLPDQ
                     LQHQNPAPCAEVKPRAGYVIFKDRHGPLQYLLMPTYRINGTESPLLLEPATPNFFWLA
                     WQARGYMSKKYGHDIPDSAVSLAINSRLGRSQDHLHIHISCIRPDVREQLDNDLTRIS
                     TRWLPLPGDLMGHEYLARRVTESELAQRSPFMMLAEEVPEARDHMGRYALAVVRQSDD
                     SFVLLATERNLLTLNRASAEEIQDHSCAILSSR"
     gene            complement(34372..35361)
                     /locus_tag="OPY25_001184"
     CDS             complement(34372..35361)
                     /locus_tag="OPY25_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCS0926839.1"
                     /translation="MKKWGVGFTLLLASTSILAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQETGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKNWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVKALFKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     TNELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTNAVAEAYLKYLYSPEGQEIAAK
                     NFYRPRDADVAKKYDDAFPKLKLFTIDEVFGGWVKAQKDHFANGGTFDQISKR"
     gene            complement(35565..36527)
                     /gene="pfkA"
                     /locus_tag="OPY25_001185"
     CDS             complement(35565..36527)
                     /gene="pfkA"
                     /locus_tag="OPY25_001185"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCS0926840.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSS
                     HQRISIVEVMGRYCGDLTLAAAIAGGCEFIVVPEVEFNREDLVAEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LEGHGGRCVGIQNEQLVHHDIIDAIENMKRPFKSDWMECAKKLY"
     gene            complement(36712..37608)
                     /gene="fieF"
                     /locus_tag="OPY25_001186"
     CDS             complement(36712..37608)
                     /gene="fieF"
                     /locus_tag="OPY25_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462942.1"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HCS0926841.1"
                     /translation="MNQTYGRLVSRAAIAATAMASALLLIKIFAWWYTGSVSILAALV
                     DSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISGSALFLTSIQN
                     LIKPTPMNDPGVGIGVTVIALICTIILVTFQRWVVRKTQSQAVRADMLHYQSDVMMNG
                     AILIALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDAERQEIID
                     IVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHFVADQVEQAILRRFPGS
                     DVIIHQDPCSVVPREGRKFELV"
     gene            complement(37756..38256)
                     /gene="cpxP"
                     /locus_tag="OPY25_001187"
     CDS             complement(37756..38256)
                     /gene="cpxP"
                     /locus_tag="OPY25_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HCS0926842.1"
                     /translation="MRKVTAAVMASTLAFSFLSHAAEVVTSDNWHPGDGATQRSAQNH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSEMETMHRLVTAEKFDESVVRAQAEKM
                     AQEQVARQVEMARVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVAQWQKSSSLKLLSS
                     SNSRSQ"
     gene            38407..39105
                     /gene="cpxR"
                     /locus_tag="OPY25_001188"
     CDS             38407..39105
                     /gene="cpxR"
                     /locus_tag="OPY25_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HCS0926843.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVLVAHDGEQALELLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGNELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQSSDNGSPTLEVDALSLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPERKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            39102..40475
                     /gene="cpxA"
                     /locus_tag="OPY25_001189"
     CDS             39102..40475
                     /gene="cpxA"
                     /locus_tag="OPY25_001189"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HCS0926844.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTSEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVEMVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSSPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRGGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETMKANQLWGEVLDNAAFEAEQMGKSLTV
                     NYPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFSVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVESAMQQHRGWVKADDSPLGGLRLTLW
                     LPLYKRT"
     gene            complement(40526..40921)
                     /locus_tag="OPY25_001190"
     CDS             complement(40526..40921)
                     /locus_tag="OPY25_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HCS0926845.1"
                     /translation="MTEAENAVAIVKEFLVASMIPDAERAATYMHPEVKITFTGGRAM
                     AGAADIAQFNGARYKWVKKALGKFDAVQHDDYVVIYSNGTLYGEWPDGRPFADNRFID
                     RFEVRDGKITRMDVWNDSAEWILAPDISR"
     gene            complement(40933..41622)
                     /gene="yiiM"
                     /locus_tag="OPY25_001191"
     CDS             complement(40933..41622)
                     /gene="yiiM"
                     /locus_tag="OPY25_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HCS0926846.1"
                     /translation="MHYPVDVFIGKIRDYDGSRPSAIAKVQIDGELMLTELGLAGDQQ
                     AEKKIHGGPDRALCHYPREHYADWIRQFPEQATLFCAPAFGENLSTDGMTEHNVFIGD
                     IYRWGEALIQVTQPRSPCFKLNFHFAISDMALLMQNSGKTGWLYRVIAPGKVSSDAPL
                     ELASRLSDVSVHEAGVIAWSMPFDDEQYHRLLSAAGLSASWSRTMQKRRLSGKIEDSA
                     RRLWGDKTPPK"
     gene            complement(41692..42312)
                     /gene="sodA"
                     /locus_tag="OPY25_001192"
     CDS             complement(41692..42312)
                     /gene="sodA"
                     /locus_tag="OPY25_001192"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HCS0926847.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     NLPEFADLPVEELITKLDQVPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAATRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            42641..43623
                     /locus_tag="OPY25_001193"
                     /pseudo
     CDS             42641..43623
                     /locus_tag="OPY25_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462935.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            43642..44157
                     /locus_tag="OPY25_001194"
     CDS             43642..44157
                     /locus_tag="OPY25_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCS0926848.1"
                     /translation="MNTFRKGLDLLLGAICCLVLAIMVGIACWQVVSRYILGVPSTLT
                     EEMLRFLLVWVSMLGMAFVAGQKQHISLTILLDKVSPTIRGWWDIILQVIFIAFSIWV
                     LIIGGLKISAISMLQISPALGIPMGKIYYALPCAGILIILYGLLNIVDALKAIHSATD
                     TTEHTLEKSHD"
     gene            44150..45457
                     /locus_tag="OPY25_001195"
     CDS             44150..45457
                     /locus_tag="OPY25_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HCS0926849.1"
                     /translation="MIDPIFASCTLIAVFVVLLAMGAPIGICIVIASFSTMMLVLPFD
                     ISMFATAQKMFSSLDSFALLAVPFFVLSGVIMNSGGIAARLVNFAKLFTGKLPGSLSY
                     TNIVGNMMFGAISGSAIAASTSIGGVMVPMSAREGYDRGFAAAVNIASAPTGMLIPPT
                     TAFILYALASGGTSIAALFAGGLVAGVLWGVGCMLVTLVVAKRRNYRVFFTVQKGMAL
                     KVAVEAIPSLLLIVIIVGGIVQGIFTAIEASAIAVVYTLLLTIVFYRTLKIKDLPSIL
                     LQTVVMTGVIMFLLATSSAMSFSMSITNIPAALSDMILGISANKLVILLVITVFLLII
                     GAFMDIGPAILIFTPILLPIMTKLGVDPVHFGIIMIYNLAIGTITPPVGSGLYVGASV
                     GKVKVEDVIKPLMPFYGAIIGVLLLITYIPEITLFLPRLLGIM"
     gene            complement(45613..>46216)
                     /locus_tag="OPY25_001196"
     CDS             complement(45613..>46216)
                     /locus_tag="OPY25_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462932.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926850.1"
                     /translation="RHEYLDDSKANYDRAYISHRFANGVGFAIEAISKSGGDDTNKAF
                     NDLETQGNEYTISYQFKTGDVAWQPGFVLETGNGYSTYKPYFRATWTLNESWWVGARY
                     RFEYVRRSSDIRDDDTINRMDVWAGYKWNNFDWTIEGIYKKADKYDLYDGGKDNYEYN
                     FRTAYIIDQWSPFVEVGNVSVNSNSDERQTRFRVGIGYTF"
BASE COUNT        11448 a        12380 c        11788 g        10600 t
ORIGIN      
        1 gtataacgat gattattgtt aaaaagacca tgaacacctc atatttgtga ccaacatcat
       61 tattcccctc cgcggattgt tttacttttt taaatgtttt ttcatctccg ataaataaga
      121 aggttaatat acattcattt tatcgataat atcgaatggg gaaataaata tgttatttac
      181 aaggaaagtc ttacctgtat tatgctgcct gtgtttgagc ggcagcgttt tggcctcagg
      241 cgttttagac ccaaacaggc caatggtcgc atcagcagat gtcattccag tacatgaagg
      301 gccattaggt atggtcgatg tcgcccccta cggcggcgtt ttcccattaa cagcaatcat
      361 taataaagcc aatcataatg tacagaacgt gaaggttacc gttttaggga aaggggaaaa
      421 aggtatccct atcagttatg atgtcggccc gcaggctata aatacccatg acggcatacc
      481 tgtatttggc ttgtatccag attatgtcaa taaggttaaa gttgactgga ctgaagaagg
      541 taaaaaacaa acttatacgt ggtccattta cgccgcaccg gtatcattac cctctactac
      601 cgggcaaact gccgttcttc ctacggtaga accggttaaa gtcgatagct cgcttaaaaa
      661 tcgcttatat ctttttaacc atataacggg gatgccaagg gcaggccaca ttatgcatgt
      721 cgcaggcggc gcggcgaact gggattatac cggtatcaac tggattagcg atacgaatgg
      781 cgatgttcgc ggctatatga atattgataa attccgtaac caggatgata taacgcgctt
      841 tggttccatg atgggcttcc atcaggttaa cgatggcaat cttatttttg gccagggtca
      901 acgttacttt aaatatgatt tcttaggccg cgttatttcc gataaacgac tgccaaaagg
      961 atttattgat ttttcgcacg ccattaccga aacgccgaaa ggcacctacc tgctgcgtgt
     1021 cgcaaaagaa aattatccat taaatggtaa atacaccatc aatactgtgc gtgatcatat
     1081 tcttgaagtt gaccagaacg gcgataccgt cgattactgg gatctgccaa aaatcctcga
     1141 cccctatcgt gacgatgtta ttctggcgat ggatcaggga gcggtatgtt tgagcgtcga
     1201 tgccgaacat tccggtcagg tcatgaccaa agagcagctt gcaaaacaac ccttcggcga
     1261 tatcgcgggc tccggcccgg gccgcaacta ggcgcatgtt aactccgtca gctacgatcc
     1321 tcgcgacgac agcattatca ttagctcgcg ccaccagtct gccatcatca aaattggccg
     1381 cgataaaaaa gtgaaatgga tactttccga tccatccggc tggaaaggcg aactggcgaa
     1441 aaaagtgctg aaacccgtag acagcaacgg taaaccgcta acctgcgaag cgcaccactg
     1501 cgacggtgga tttgactgga catggacaca acataccggt tggttagtgc catccaaaag
     1561 caccggaggt aaaaccgtcg tgaccgcctt tgataacggc gatgcgcgcg gcatggaaca
     1621 accggccatg ccgtcaatga aatattcccg cggcgtggaa tatcagattg acgaaaaaat
     1681 atgacggttt cccaaatgtg ggaatatggt aaagagcgcg gttttgactg gtacagcgcc
     1741 attacttccg tcacggaata tcgcccggaa accaaaacga tgttcatgta ctcggccaca
     1801 gcgggaatga gcggtacaaa tccaatcgtt tccgttctgg atgaagtcaa agacggtact
     1861 caggatgtga tgctggagct aaaagtacac agtaaccgtg ctggtatgct gggttatcgg
     1921 gcgctgatta tcgatccaga gcagatgttt aaaaaataaa gcgtgagagt aaaagtaaaa
     1981 caggcggaag ccaacttccg cctgaatggt taaaacgtat tgtagttatg acattcgcct
     2041 tattgccctc ggagaggaat gcaaaaatat caatgaatta ccaatccggc accgacccga
     2101 taagcgcagc gtcattagac aaacgccaca acataccgcg cctttgctgg tgatatgtca
     2161 tgaaaaatct ctttatcgcc tggttaagtt tattgctata tggctgcaca acctttccac
     2221 aagccgtaaa acctacgaca ggcggacagc cctccccgac ggaaatctat atcgtcagtc
     2281 atggctggca cacgggaatt attgcgccgg cccatgatgt taataccgtt ctgccacagc
     2341 ttaaaaaacg gttcgctcag gagacgcagt ggtatgaaat cggctggggc gataagggct
     2401 tttatcagtc acaagaaata accaccgcgc ttacgctcca ggccatgttc tggtcatccg
     2461 gcgcggttat gcacatcgtc gccttttccg gtcaaccaga acgctatttc gccggtagcg
     2521 agataaaatc actgctcctg cacacaaacc agcgtaacag tctgatgcgt tatctgggcc
     2581 gcagctttgc gcgtgacgca gagggtaatc tgattccgtt aaaacaagga atttacggcg
     2641 atagccagtt ttacgccgcg aatggccgct acggcatact caatacctgc aataaatgga
     2701 cagcgaaggg gctggaaagc gcgggactga ctataaatcc ttcgttaaaa ctcacggcag
     2761 gaagcgtaat gaaagcgatt acggatcaca gaatgtgtct gaacaaatac tgttatccct
     2821 agaaaacaaa aaaagcgccc tgcggcgctt ttttttctgg cggtaactta tttgctgcca
     2881 gggatgctga agcgcttgtt gaagcgctca acacgaccac cggtatcaac aacacgctgc
     2941 ttaccagtga agaacgggtg gcatttgccg cacacgtcca ggttcaggtc gtgacccacg
     3001 gtagagtggg ttttgataac attaccgcaa gaacaggttg cagtaatttc tacgtaattc
     3061 gggtgaatac cttttttcat ggggaacctc agtgtaaggc cgcgtcgctc ttccagccct
     3121 aacgccagac accacgcgaa gttaatagta aagggtttga tgctcacaac acgcaccaaa
     3181 ggcggcgaat catacagaat ttgaccaccg tatgcaaact gatccgcgct cccttatcgt
     3241 aatgtgtata ctacccgacg aaatttcaag tcaggaagat gctatgtccg tcgcgcacgt
     3301 tgccttgccc gttccgcttc cccgaacctt tgattacctg ctgccggaag gcggggtcgc
     3361 caaagccggg tgccgcgtgc gcgtgccgtt cggcaagcag caagagcgcg tgggcattgt
     3421 cgtctcggtt agcgaccaca gcgaattgcc gctcgatgaa ttaaaatcgg tcattgaaat
     3481 cctggataac gagccaatct tttctccctc catctggcgc ttactcctct gggcggcgga
     3541 ttactaccac catcccctcg gcgacgttct gtttcacgct ctgccggttt tactgcgtca
     3601 gggaaaacca gccagcaacg cgcccctatg gtattggttc gccaccgaag aggggcaagc
     3661 cgtcgacatc aacagcctga aacgctccgc caaacaacaa caggcgctgg cggcgctgcg
     3721 gcaaggaaag atctggcgct atcaggtagc cgagcttgat tttactgacg ccacgctgca
     3781 aacgctgcgg cgtaaggggc tttgtgagct tgccagtgaa acgcccgcgt ttaccgactg
     3841 gcgggagcat tatgccgtcg caggagagcg cctgcggcta aataccgaac aggcgacagc
     3901 agtcggcgca attcacagcg cgtcggacgg tttctccgcc tggttgctgg caggcgtaac
     3961 cggttccggc aagaccgaag tgtatctgag cgtgctggaa aacgtcctcg cccagggcaa
     4021 acaggcgctg gtgatggtgc cggaaatcgg cctgacgccg caaacgatcg cccgttttcg
     4081 cgaacgtttt aacacgccgg tggaagtgct gcattccggg ctaaacgaca gcgagcgtct
     4141 ttcggcatgg ctgaaagcga aaaacggcga agcggcgatt gtcatcggca cgcgctcctc
     4201 gctgtttacg ccgtttaaaa atcttggcgt aattgtcatc gacgaagagc acgacagctc
     4261 ttataaacag caggaagggt ggcgctacca tgcccgcgat ttggcagtgt atcgcgccca
     4321 tagcgagcag atcccgatta ttctcggctc cgccacccca gccctggaaa cgctatgcaa
     4381 cgtgcggcag aaaaaatacc ggatgctgcg tctgacgcgg cgcgcaggca acgcccgccc
     4441 agccctgcag catgtgctgg atttaaaagg acagcgtctt caggcgggac tggcgcccgc
     4501 ccttatcgcc cgtatgcgcc aacatctcca ggccgataat caggtaattt tatttcttaa
     4561 ccgccgggga ttcgcgcccg cgctgctttg ccacgactgc ggctggattg cggagtgccc
     4621 gcgttgcgat cactactaca cgctgcacca ggcgcagcat catttacgct gccatcactg
     4681 cgacagccag cgtccggtac cgcgtcagtg cccctcctgc ggctccacac atatgctacc
     4741 ggttgggtta gggaccgaac agctggagca ggtgctggcg cccttcttcc ccggcgtgcc
     4801 gatctcacga atcgaccgtg ataccaccag tcgtaaaggc gcgctggagc agcatctggc
     4861 ggaagttcac cgcggcggag cgcgcattct gataggcaca caaatgctgg cgaaaggcca
     4921 tcacttcccg gacgtcacgc tggtggcgtt gctggatgtc gatggcgcgc ttttttccgc
     4981 agattttcgt tcggcggaac gcttcgccca gctctacact caggtttccg gccgcgccgg
     5041 gcgcgcgggt aaacagggcg aagtggtgct ccaaacgcac catcctgagc atcccctgct
     5101 gcaaacgtta ctgtataaag gctatgatgc gtttgcggaa caggcgctgg cggaacggca
     5161 aacgctccag cttccgccgt ggaccagcca cgtcattatt cgcgcagagg atcacaacaa
     5221 tcagcaggcg cccgtctttc tccagcagtt gcgtaatgtg attcaggcca gcccgctatc
     5281 agacgataag ctgtggatct taggtccggt tccggccctc gcgccaaaac gcggcggccg
     5341 ctatcgctgg caaattttac ttcagcatcc ttcacggatt ctcctgcaac acatcatcag
     5401 cggcacgctg gcgttgatca atacgctccc tgaagcgcgg aaagttaaat gggttctgga
     5461 cgtcgatccg attgaaggat agtccccacg atgcgaggcg gatcgtaaaa ttaaagatcc
     5521 atcacacttt ttatgaaaat tctgtaaccg cttccacgca ctatctgata aaaatgtttt
     5581 cgatgagtgt taccagggat agatctgcgc cagcagttcc caggcgagga gaaagagtga
     5641 aatcgaacaa gcaggttact gccgctacga tgaaggatgt tgcgttgaag gcgaaagtct
     5701 ctacggcaac cgtatcccgc gcgttaatga accccgataa agtctcccag tcgacccgta
     5761 gccgggttga acaggccgcg cttgaagtgg gttatttccc gcagtcgatg gggcgaaatg
     5821 taaaacgcaa tgaatcccgt acgattttgg tgattgtccc ggatatttgc gatcccttct
     5881 tcagtgaaat tatccgcggt atcgaagtga ccgcggcaga acaggggtat ctggtgctga
     5941 ttggcgattg tgcccatcaa aaccagaaag aaaaaacctt tcttaatctc atcatcacca
     6001 aacagatcga cggcatggta ctgctcagtt cccgactgcc ctttgacgcc agcgttgagg
     6061 agcagcgcaa tttgcctccg atggtgatgt cgaatgagtt tgcgccggag cttgaattgc
     6121 cgacggtaca tatcgataac ctgaccgccg cgttcaatgc catgaactac ctgttggatt
     6181 tgggccacaa gcggattggt tgtattgcgg ggccggaaga tatgccgctc tgtcactatc
     6241 gcttacaagg ttacgtacag gcattaagac gcagtggcat tgtggtcgat ccgcattaca
     6301 tcgcccgtgg cgactttacc tttgaagccg gggcaaacgc attaaagcag ttgcttgagc
     6361 aaccgttgcc gcctaccgcc gtcttttgtc atagcgacgt aatggcgctg ggcgccctct
     6421 cctgggccaa gcgccagggt ctgaaagtgc ctgacgatct gtcgattatc ggctttgaca
     6481 atatcgcgct ggccgagttt tgcgaccctc cgttgacaac cgtggcgcag ccgcgttttg
     6541 acattggtcg cgaggcgatg ctgctgttgc tcgatcagat gcaggggcaa aatgtgagca
     6601 gcggctcgcg tttaatggat tgcgagctga ttattcgcgg ttctacacgc gctttaccct
     6661 aaagtaaata gctttaagac tcacctgtct ggtcaaaggc ccgccgcttc agtaacatga
     6721 cgggctgacg aacgaataaa tacagcgaaa cgatagtggc acaacgagat tatgtacgtc
     6781 gcggccaacc ggctccttcg cggcgcaaaa agagcacctc acggaactca cggaagaagc
     6841 aaagcaacat gcctgccgtc tcgccggcaa tggtcgcgat tgcggcagcc gtccttgtga
     6901 cctttatcgg cggtctgtac ttcattactc accataagaa agaagagtcc gaaacgctac
     6961 aaaaccagaa agtcaccggc aatgggcttc cgccaaaacc ggaagagcgc tggcgttaca
     7021 tcaaagagct ggaaagtcgc cagccgggcg tgcgtacgcc aacggaaccg tccgccggcg
     7081 gcgaagtcat gaatccgaat cagctcacca gcgagcagcg tcaactcctg gagcagatgc
     7141 aggcggatat gcgtcagcag ccgacacaac ttaacgaagt gccgtggaac gagcagacgc
     7201 cagaacaacg ccagcaaacg ctacagcgcc agcgtcaggc gcagcagcag cagcagcagc
     7261 agtgggctca aacgcagcct gttcagcaac cacgcacgca gccgcgggta aacgaacagc
     7321 cgcaaacgcg cacggtacag tccgccccgg cgcaacccgc gcgccaaagt cagccgccga
     7381 agcagacggc ctcgcagcaa ccttatcagg atttgctgca aacgccggcg cataccagcg
     7441 cggcagcgcc aaaagccgcg cccattacgc gcgcgcctga agcgccgaag gcgacagcag
     7501 agaaaaaaga tgaacgtcgc tggatggtgc aatgtggttc attcaaaggc gccgagcagg
     7561 cagaaagcgt ccgcgctcag ctggcgtttg aaggctttga ctccaaaatt accaccaata
     7621 acggctggaa tcgcgtggtt atcgggccgg tgaaaggtaa agaaaatgcc gacagcacca
     7681 ttaaccgtct gaagatggcg ggccatacaa actgcattcg actcgccacc gggggttgaa
     7741 accctcaaaa tctcccccat ctatacttgc attatgcccc gtacgccgta cggggccgca
     7801 attcagcatt agtaaccaag gggtctgctc gtgacaacaa tagtaagcgt acgccgtaac
     7861 ggccacgtgg taatcgccgg tgatggtcag gccacactgg gtaacacagt aatgaaaggc
     7921 aacgtgaaga aagtccgccg cctctacaac gacaaggtca ttgcgggctt tgcgggcggt
     7981 actgctgatg cattcacgct gttcgagctg tttgaacgta aactggaaat gcatcagggg
     8041 cacctggtca aagccgccgt tgaactggcg aaagactggc gtaccgaccg tatgctacgc
     8101 aaactggaag cgttgctggc cgtcgcggat gaaaccgctt cgctcatcat cacgggtaac
     8161 ggcgatgtcg tgcaacctga aaacgattta attgctatcg gctccggcgg tccttatgcc
     8221 caggctgccg ctcgcgctct gttggaaaat accgagctcg gcgcgcgcga aattgctgaa
     8281 aaggcgttgg atattgcagg cgatatctgc atttacacca accatttcca caccattgaa
     8341 gaattgaccg ccaaagcgta aggacctctc atgtctgaaa tgaccccacg cgaaattgtc
     8401 agcgaactga acaaacacat tatcggccag gataacgcaa agcgttccgt ggcgattgca
     8461 ttgcgtaacc gctggcgtcg tatgcagctt gatgaagagc tgcgccacga agtaacgccg
     8521 aaaaatattc tgatgattgg cccgaccggc gtcggtaaaa ccgaaatcgc ccgtcgtctg
     8581 gcaaaactcg ccaacgcgcc gttcattaaa gtcgaagcca ccaaattcac cgaagtgggc
     8641 tatgtcggga aagaagtgga ctctatcatc cgcgatctga ccgatgccgc tgtgaaaatg
     8701 gttcgcgtac aggctatcga gaaaaaccgc tatcgtgcgg aagagttggc ggaagagcgt
     8761 attctcgacg tactgatccc acccgcaaaa aataactggg gccaggccga acagcagcag
     8821 gagccttctg ccgcccgtca aacgttccgc aaaaaactgc gcgaaggcca gctcgacgat
     8881 aaagagatcg agattaacct cgccgccgcg ccgatgggcg tagagattat ggcgcctccg
     8941 ggcatggagg agatgaccag ccagttgcag tctatattcc agaacctagg cggtcagaaa
     9001 cagaaaccgc gtaagctgaa aattaaagac gcgatgaaac tgttggttga agaagaagct
     9061 gctaagctgg tcaacccgga agagctgaaa caggacgcta tcgacgcggt tgaacagcac
     9121 ggcatcgtgt ttatcgatga aattgacaaa atttgtaagc gtggcgaaac ctccggcccg
     9181 gatgtttcac gcgaaggcgt acagcgcgac ttactgccgc tggtagaagg ctgcacggtt
     9241 tcgaccaaac acgggatggt caaaacggat catattctgt ttatcgcctc tggcgcgttc
     9301 caggtggcga agccgtctga tctgatcccg gaactgcagg gccgtctgcc gattcgcgtt
     9361 gaacttcagg cgctgaccac cagcgatttc gaacgcattt tgaccgagcc aaacgcctcc
     9421 gtcactgtgc agtataaagc gctgatggca actgaaggcg tcaatatcga gttcaccgat
     9481 tccggtatta aacgtattgc cgaagccgcc tggcaggtta acgaaaccac cgaaaacatc
     9541 ggcgcgcgcc gtctgcatac cgtactggag cgtctgatgg aagaaatttc ctataacgcc
     9601 agcgatttgc acggccaaaa catcacaatt gatgcggaat atgtgagcaa acatctggat
     9661 gcgctggtcg cagatgaaga tctaagccgt tttatcttat aatcgcgtcc aatgcatttt
     9721 catcactgtt gatggggctg aaaagcccca tttttattgg cgctaaatat gactgaacaa
     9781 caacaaatta gccgcaccca ggcctggctg gaaagcttac gacccaaaac cttacctctc
     9841 gccttcgcgg cgattatcgt cggtacggcc ctggcatggt ggcaaggcta tttcgatcct
     9901 ctggtcgcac tgctggccct tatcaccgcc gggctgttgc aaattttatc caacctcgcc
     9961 aacgattacg gcgacgctgt caaaggcagt gataaaccgg atcgcatcgg accgctgcgg
    10021 gggatgcaaa aaggcgtcat cacccagcag gagatgaagc gggcgttaat cattaccgtc
    10081 gtgctgatct gtatctccgg actggcgctg gtggcggtcg cgtgccatac gttaaccgat
    10141 tttgtcggct tcctgatttt gggcgggctg tcgattatcg ccgccatcac ctacaccgtg
    10201 ggtaatcggc cctacggtta tatcgggctg ggtgatatct ctgtcctggt attctttggc
    10261 tggctaagtg tcatggggag ctggtatctc caggcgcata cgctgattcc ggcgctgatt
    10321 ctcccggcca ccgcctgcgg tttactggcg acggcggtgc tgaatattaa taacctgcgc
    10381 gatattaata gcgacagaga gaacggcaaa aacacccttg tggtacgact tggcgatgtc
    10441 aacgcgcgtc gttatcacgc ctgcctgttg ctaggcgcgc tgctctgtct ggcgctgttt
    10501 aatctgctct cgctacacag tccgtgggga tggttgttta ttctggccgc gcccttgctc
    10561 attaaacaag cgcgctacgt aatgcgcgaa agggagcctg cggcaatgcg cccgatgctt
    10621 gaacgtaccg ttaaaggcgc gttgttaacc aacctgttat ttgtgattgg gatactctta
    10681 agtcagtggg ccgtttaact gacaaatatc aattaacaat tgatgatttt gccaacagta
    10741 tacttagcgc gatatactaa aaattctcgc agcaactgaa cgttaagcct atgaaatacg
    10801 atacttccga gctttgtgac atctatcagg aagatgtcaa cgtcgtggaa ccgctgttct
    10861 ctaattttgg agggcggtcg tcgtttggcg gacaaatcat cacggtaaaa tgtttcgagg
    10921 acaacgggtt gctgtacgat ctgctcgaac aaaatggccg tggtcgggtt ctgctggtcg
    10981 atggcggcgg ttctgtccgt cgtgcattag ttgatgcgga gctggcgcgt ctggccacgc
    11041 aaaatgaatg ggaagggctg gttatctatg gcgcggtgcg tcaggtggac gatctggaag
    11101 agctggatat cggcattcag gcgatcgccg ccattccggt tggcgccgca ggtgaaggca
    11161 ttggggaaag cgatgtgcgc gtcaatttcg gcggcgtgac gttcttctcc ggcgatcatc
    11221 tctatgccga caacaccggg attatccttt ccgaagaccc gcttgatatc gagtgatcaa
    11281 aaaaggcgcc gtaaggcgcc ttttttatgc gttgtcgctg attgccggat gtcggcttac
    11341 gccttatccg gcccaccggt atccgcattc taaatcctct atagatttcg cgtcagggca
    11401 aggcggcaag aaagtgaatc cccaggagca taggccacta tgtgactggg gtgaacgcac
    11461 gcagccaacg ccgccataac gtgaaatatg acgaggatta gacttcttcc atacgaccaa
    11521 gcagcgcctg taaacgttcc tgccagccgc tctgctgttc cttcagaaaa ttattttcac
    11581 gctcgagttc ttcacgctga tgctgtgcag actgcacttc ctgcgtcagg ctgttgttct
    11641 tttctttcag ctcttcaatt tccatctgta acagggtgat ggtgtcaatc gcctgctgta
    11701 cttttgcttc cagtttctca aacacttcta aagacatgat cttacctctc ctgaattgca
    11761 aggcgacgct tcacgtaaac gcgcacaata tatagtatcg attgtatgaa gccccgctct
    11821 cgctgtccag cgacataccg cgtagatcgc ggtttgcagc aattttcatc catctcctgg
    11881 taacattcat tcaataactt aaaagtgtta acatattggt taatgaaatg attcaattca
    11941 ctctcttctg ctgtctcaaa atgcgcctca tggcgcgata acgctcattt tattgacgca
    12001 gtacacacat tttgatttcg atatttctcg tttttgctcg ttagcgataa attaacagtg
    12061 tgcctacagg gcatcgtgga tgtccatgac ctcctcgcat accaataatc attacatact
    12121 cttcaggatc cgattatgag tcaaacatca accttaaaag gccagtgcat tgctgaattc
    12181 ctcggtaccg ggttgttgat ttttttcggg gtgggttgtg tcgctgcgct taaagttgcc
    12241 ggagctactt ttggacagtg ggaaatcagc gtcatctggg gtctgggagt agcgatggct
    12301 atctacctga cggcaggtgt ttctggcgca cacctgaacc cggcagtgac catcgcactc
    12361 tggctatttg cctgtttcga caaacgtaaa gttgttcctt ttattatttc tcaagttgcc
    12421 ggcgcctttt gcgcagcggc gttagtttac gggctttatt acaatctttt tgtggacttc
    12481 gaacaaaccc accatatcgt ccgtggcagc gttgaaagtc tcgatctcgc aggcattttc
    12541 tcaacttacc cgaatcctca tatcaatttt gtgcaggcct tcgcggttga aatggtgatt
    12601 accgctattc tgatggggct gattctggcg ctgaccgacg acggtaacgg cgtacctcgc
    12661 ggtccgcttg cgccactgct cattggttta ctgatcgccg ttatcggtgc ctctatgggg
    12721 ccgttgaccg ggtttgcgat gaatccggcg cgtgactttg gccccaaaat gttcgccggg
    12781 cttgccggct ggggtgaaat tgcgtttacc ggcggtagag acattcctta cttcctggtg
    12841 ccactgtttg gccccatcgt cggcgccatt ctgggcgcgt ttgcttatcg caaatttatt
    12901 ggccgtcatt tgccgtgcga tatctgcgtc gtggaagaga aggactccac cgcggccaca
    12961 caacaaaatg cttcgctgta atctgattac gggacaaaat tatgactgaa aaatatatcg
    13021 ttgcgctcga ccagggtacc accagctccc gcgcggtcgt tatggatcat gacgcgaata
    13081 tcgtcagcgt atcacagcgt gaatttgagc aaatttatcc taagccaggc tgggtagaac
    13141 acgacccgat ggaaatttgg gcgtctcaaa gctcaacgct ggtagaagtg ctggctaagg
    13201 ccgatatcag ttccgatcag attgccgcta tcggtatcac caaccaacgt gaaaccgcga
    13261 tcgtctggga acgtgaaacc ggcaaaccga tatacaacgc tattgtctgg cagtgccgtc
    13321 gtaccgccaa tatttgcgaa cagcttaaac gcgacggcct ggaagattac atccgcgaca
    13381 ataccggtct ggtcgtcgac ccgtacttct ctggcactaa agtgaaatgg atccttgacc
    13441 atgtggaagg ttcgcgcgaa cgcgcgaagc gtggcgagct gctgttcggt acggtggata
    13501 cctggcttat ctggaagatg acgcagggcc gcgtccacgt tacggattac accaacgcct
    13561 cacgaaccat gctgttcaac atccatgatt tggactggga cgataaaatg ctggacgtgc
    13621 tggatatccc acgcgcgatg ctgccccagg tacgtaaatc ctccgaagtc tacggccaga
    13681 ccaatattgg cggtaaaggc ggtacacgta ttcctatcgc cgggattgcc ggggatcagc
    13741 aggccgcgct cttcggccaa ctgtgcgtaa aggaaggaat ggcaaagaac acctacggca
    13801 ccggctgctt tatgctgatg aacaccggcg agaaagcggt aaaatcggaa aacggcctgc
    13861 tgaccaccat cgcctgcggc ccaagcggcg aagtcaacta tgcgctggaa ggtgcggtgt
    13921 ttatggcggg agcgtccatt caatggctgc gtgatgaaat gaagctcatc agcgacgcat
    13981 tcgactccga atatttcgcc acgaaagtga aagataccaa cggtgtctac gtggttccgg
    14041 ccttcaccgg tctgggcgcg ccgtactggg atccgtatgc ccgcggcgcc atttttggcc
    14101 tgacccgcgg cgtgaactct aatcacatta tccgcgcgac gctcgaatcc atcgcttacc
    14161 agacccgcga cgtactggaa gcgatgcagg ccgactccgg tatccgcctg cacgctctgc
    14221 gtgtggacgg cggcgcagtg gccaacaact tcctgatgca gttccagtca gatattctcg
    14281 gcacgcgggt ggaacgcccg gaagtgcgcg aagtgaccgc gctgggcgcc gcctatctgg
    14341 ctggcctggc cgtcggttac tggcagaacc tggacgagct gcaggaaaaa gccgtcattg
    14401 agcgagaatt ccgccccggc attgaaacca ccgagcgtaa ctaccgttac agcggctgga
    14461 agaaagcggt taaacgcgca atggcgtggg aagagcacga caagtaaggt cgccatccgg
    14521 caaaatcttt gtgcggaggc aactccgcac acacatcaat tattccctcc ctcccctgtg
    14581 ctacactgcg cgccactcct ttttgctacg agtttgttat gagacgagaa cttgccatcg
    14641 aattttcccg tgtgaccgaa gcggcggcgc tggctggcta caaatggctg ggacgcggcg
    14701 ataaaaatac cgcggacggc gcggcggtca acgccatgcg tatcatgctc aaccaggtca
    14761 acattgacgg caccatcgtg attggcgaag gcgaaatcga cgaggccccg atgctctata
    14821 tcggcgagaa agtcggtacc ggccacggcg atgcggtaga tatcgccgtc gatccgattg
    14881 agggcacgcg catgacagcg atgggtcagg cgaacgcgct ggcggtactg gcggtcggcg
    14941 ataaaggctg cttcctgaat gcgcccgata tgtatatgga aaaactgatt gtcggtccgg
    15001 gcgccaaagg ggcgatcgat ctcaatctgc cgctggcgga taacctgcgc aacatcgcgg
    15061 atgcgctggg taaaccgctt ggcgatctga ccgtgaccat tctggcaaaa ccgcgtcatg
    15121 acgaggttat cgcagagatg gccaaactgg gcgtacgcgt gtttgccatt cctgacggcg
    15181 acgtcgcggc ctcaattctg acctgtatgc cggatagcga agtcgacgtg ctgtacggga
    15241 ttggcggcgc gccagaaggc gtggtatccg cagcggtgat ccgcgcgctg gacggcgata
    15301 tgcagggacg tctgctggcg cgccatgacg tgaaaggcga cagcgaagaa aaccgccgca
    15361 ttggcgaaca ggaactggcg cgctgcaaag caatggggat tgaagcgggc aaggcgttat
    15421 gcctgggcga catggcgcgt agcgataacg ttattttctc tgcgaccggc atcacgaaag
    15481 gcgatctgct ggaaggaatt agccgaaaag gccatatcgc cacgacggaa acgctgctga
    15541 tccgcggcaa atcacgcacc atccgccgca ttcagtctat ccactatctt gatcgtaaag
    15601 atcctgatgt gcaggcgcat atcctctagc gcatttgtta gttagagcct tccagcctcg
    15661 cggggctgga aatctttctc ctgacgaacg aagataaggt tagcgattca gaacaggaga
    15721 aaaccatggc cgattgggta acaggtaaag tcactaaggt gcaaaactgg actgacgcac
    15781 tgttcagcct gaccgttcac gcccccatta atccttttac tgcaggccaa tttaccaaac
    15841 tcggactgga gatcgatggc gagcgcgttc agcgcgcgta ttcctatgtg aatgcgcctg
    15901 acaatccgaa tttagagttt tatctggtga cggttccgca aggaaagctc agcccgcggc
    15961 tggcggcgct aaaacctggc gatgaggtac aagtggtcag cgacgcgtcg ggtttctttg
    16021 tactggatga agtgcctgac tgcgagacgc tatggatgct ggcgaccgga accgctattg
    16081 gcccgtattt gtctattctg caatatggcc aggatgtcac gcgctttaaa aatctggtct
    16141 tagtccacgc cgcacgcttc gccgccgatt taagctatct gccgctaatg ctggaactgc
    16201 aacagcgtta tgaaggcaag ctgcgcatcc aaacggtggt cagccgggag agcgtgccag
    16261 gctcgcttac cgggcgcgtg cctgcgctca ttgaaaacgg cgagctggaa aaagccgttg
    16321 gattaccgat ggataaagag accagccacg tcatgctgtg cgggaacccg cagatggtgc
    16381 gcgatacgca gcaactgctg aaagagaccc gacagatgac taaacatctg cgccgccgac
    16441 cggggcatat gacggctgaa cattactggt gatgttttac cgaatggcag ctagggctta
    16501 tccggcctgc aaatcatcac caatctgtag gcccggtaag cgtcagcgcc accgggcaaa
    16561 ttacggttta ccgcccgttt acggttctgc cttaaacttc acgtcctgtg tcgctttccc
    16621 aaacttattt tccccctgaa caccgacaaa cgcgcccaga tcgataagca tcatcaccag
    16681 gatcagcgtc ggaataaatc gcccgacgac ccactgccac atccccggca acatcaccca
    16741 gtttccggcc agcagcatcc acgccagaat cattagcaac gcccacgcgc cggaacgtcc
    16801 ccggtcatgc agacgtttga ccatgacggc ggcggtcggc cacagcaggc acaccaggca
    16861 aaatgccgcc gtttggatat caagcaggtt tttccccgcc agcgaaaata gcgccagcat
    16921 cccggcaaac cagaggccga tccaaatcca gaaatcacgg cgtccgatac gccctttaaa
    16981 tgagaataac cattgctgta tggtcatgta agttccttat attttgcctt ccgctacagt
    17041 ttaccctttt gacaagcccg acagttatcg ttttaatcgt gagcagtcct aacgaaaggt
    17101 aagattgatg aagccaggat gtactctgtt tttactgttg ttttctgctc tcaccgccag
    17161 cataacggcg cacgcgcagc tctcttcatc gaccacgaca gcgccctatc tgctggcggg
    17221 ctcgccaacc tttgatcttt ctattagcca gtttcgtgag aactttaacc gccagaatcc
    17281 cgatctgccg ctcaatgaat ttcgcgccat tgagaatagc cgcgataagg cgaatctgac
    17341 ccgcgccgcc agtaagatta acgaaaatct gtatgcctcc acggcgctgg agcgcggtac
    17401 gctcaaagtg aaaagtatgc agattacctg gctgcccatt caggggccgg aacagaaagc
    17461 ggcgaaagcg aaagcgctgg aatatatggc cgccattatt cgcactgtcg ccccgttact
    17521 gacaaaagag caaagccaga aaaaactgca aaagatgctt atcgccggta aaggtaaaca
    17581 ctattacgcc gagaccgaag gcgcggtacg ttatgttgtc gcagataacg gcgaaaaggg
    17641 gctgaccttc gcggttgaac cgattaagct ggcgttatct gaaaatctgg aaggggcgaa
    17701 ttgatgacaa aaagcaaagc ctttccgggg atgaatctct atactgtttc acagaccatg
    17761 ctgctctgac gagcggccat cttccttaat tcgctgacta agcgtggaga aatgaaatgc
    17821 gacatccttt agtgatgggt aactggaaac tgaacggcag ccgccacatg gtaaacgaac
    17881 tggtggctaa cctgcgtaaa gaactgacgg gcgtagcagg ctgcgacgtg gcaatcgctc
    17941 cgccggaaat gtatatcgat ctggcgaaac gcgctgctgc cggcagccac atcatgctgg
    18001 gcgcgcagaa cgttgatctg aatctgtctg gcgcattcac cggtgaaact tcggctgaaa
    18061 tgctgaagga tatcggcgcg cagtacatta ttatcggcca ctccgagcgt cgtacttatc
    18121 acaaagaatc tgacgagctg atcgccaaaa aattcgccgt actgaaagaa caaggtctga
    18181 cgccggtact gtgcatcggt gaaaccgaag cggaaaacga agcgggcaaa acagaagaag
    18241 tgtgcgcacg ccagatcgac acggtactga aaacgcaggg cgcggcagcc tttgaaggcg
    18301 cggttatcgc ttacgaaccc gtatgggcga tcggtaccgg taaatctgca actcctgcgc
    18361 aggctcaggc agttcacaaa ttcatccgtg accacattgc taaagctgac gcgaaaatcg
    18421 ctgaacaggt tattatccag tacggcggtt ctgttaatgc gtccaacgca gccgaactgt
    18481 tcgcgcagcc ggacatcgac ggcgcactgg taggcggcgc ttctctgaaa gctgacgcct
    18541 tcgccgtgat cgtgaaagca gcagaagctg ctaaacaggc ttaattgcca atcaatgtct
    18601 gatggcgctg cgcttatcag gcctaccagc cgagtgctta tgtaggcctg ataaggtaaa
    18661 gccgccatcc ggcatttatg ccgtggaggg taagaaagta gtatccccgg caaccttaaa
    18721 catcgccctc cagctccgcg tattctcaac cagccgatca tcacgaaata acgcactacc
    18781 agaaacaaca cgatcgatgc cctgtgcaat cagcgaaggc aactgatcct gcgttaacga
    18841 cccatcaata acgataattt taccttcgcg tttatcacca agtagacaga gaagctgtgc
    18901 cacgcgctcg tacaaatcac tggagcgcat tttactgccg tatccagggt tcactgccag
    18961 tagttgaata acctcaacgt cgctcagaat agggataatg acatccagag gcgttgccgg
    19021 gcataaacta atcccccgga tcaccggcat ttcaccgtca ataacgggca cggtctgctg
    19081 accaagccag cttagcgtat gatgcagatg aatatcgcct tcagcctgaa gcgtgatgca
    19141 gtgtgcgccc gctttcacgc aggcttgcgc cgccgcccat tgatccgcta ccatcaaatg
    19201 aacatctttg ataaaagttt gcggcagttg cccaactgcc catggcccaa cggtaaactg
    19261 tgggcaaaat tgaccatcca tcaaatccaa atgcaacagc ggctggttta acgcttccaa
    19321 ctgttgcaga tagcgatgca acgcaatcca ctgccctgcc agaataccca cactaagcgg
    19381 atatgacgct aacaatgcca cacatgcttc gcgcgttaat ccggcaaact ggctgttcat
    19441 gagcgctcct taaggcatca aacccataaa aacttttttt gtccgcggac cggtcatcaa
    19501 cggttcaagc tgctccacgc aagttttata gtgtggcgtt gtcttgtgaa aagcgacggc
    19561 ctgttcatca acgtaggctt cataaatata aaatcgcgta ggcacctgcg gatcctgcag
    19621 aacatcaaaa cgcaagttac ccggctcttt aattgagccc agatgattct gccgaaaaac
    19681 atcgataaat tgttcaacct tgtcatcatg aacgttaatt tcaaccagcg taacgtgcat
    19741 cattaacccc ctgattattc caaataaaat aacagtcatc cccatctcct cgcatcggta
    19801 aaagatgggg aagcgatctc atttaacctt tctcactcaa aaacagctca taagcacgct
    19861 ctgctgtttc gttatgatga acgacagcat gtaccgcttt aatcatggct accggatctt
    19921 ctgactggaa tatattacgc cccatatcta cgccagaagc cccctggtca atcgcctgat
    19981 agcacatttc caatgcttca cgttcaggca gttttttacc gccggcgatg acaatcggca
    20041 ccggacaacc tgccgcaata cgctcaaaac ctttatcgac ataatacgtt ttgataattt
    20101 gcgcccccat ttccgcagcg atacgcgttg ccagtgaaaa ataacgctgg tcgcgagcca
    20161 tatctttacc caccccggtc actgccatta ttggcatccc gacgcgtaac ccggcatcaa
    20221 tcagttgaat aatattttta atcgactgat gttcatgttc actaccaata taaacctgtg
    20281 cggcagcagc acagctattc aaccgcacag cgtcatccat cgccaccgca accgcctcat
    20341 tgcttaattc agtgagaata gaatttgccc cggacgcgcg taaaacgact ggtttattga
    20401 ttgccggagg taccacactg cgtaatatgc cgcgagtaca cattaagaca tcagcatatt
    20461 caaagagcgg cgcaatattg atatcaatac gctcaagtcc ggttgtcggc ccctggaaat
    20521 atccatggtc aaaggccagc atgaccgttt tcctggtcct aggattaaaa atcctcgcca
    20581 gtctggactg cattccccaa tccagcgcgc cacagccttt taatgagaac aaagtgttag
    20641 tttgtggttt atcggtgtga aaatctttgc catctttaat atcatctaaa tcagccattc
    20701 tttactccgt cgatacataa cagttatcag aaatcatatt tgtcgatatt gtctttgttg
    20761 aaaatgacac gctctggcaa taacacaatg ccgttacctt ttgcctcata gtgatatccc
    20821 tgctcactat taggtgaaac ggtgactttg ccgatgccgg gaatatccag tgaatcaccg
    20881 acattcattg gcatattttt cagcaacgcg ttggcgacat atacggaaat ttttccctgt
    20941 tggacgacat cccacaggcc aaactcttta acagtgccgc gctgaacata agggcgcatt
    21001 acattcggcg tactaaaacc aacaatcgcg agattattac gtttaaggtt ctccgccgcc
    21061 tgtgccgcag caggtaaagc gttagcgtca ggcgcgatga tggcatccag atcgggatac
    21121 gctttgatga taccttccgc cgtctggagc gatttcgtgg catcgttata gccaaactgg
    21181 gtagtgacta tctcccaccc tggatgttcc tggctaattt tggctttagc ttcttttacc
    21241 cactggttct ggtcggtcac cgttgggctg gaatagaaga aagcgacttt cgctttctct
    21301 ttgtccacct gatgagcggc catctctacc agcatgctgc cgagctgttt tggcgtccct
    21361 tgattgatat agtaagaacg gcactccggc ttggtatcgg aatcccaggt taatattttc
    21421 acgcctcttt gcattgcccg cttcaacgcc gggcacaggc catcaggcga aacggcagaa
    21481 acgataatgg cgtcataccc ctgattgaca aagttattca ccagttgaac ctggcctgag
    21541 acgctgggct ctgtagggcc atcgtaagtt acgtcaatgc ccagcgcttt tcccgcttcc
    21601 tgcgcgccat tgccgccgct ggtaaaaaag cccacgccaa ccagtttggg aataaaagca
    21661 atccgctctg ccgcctgcac ggtcattacc gcagatgcca gaccaaacgc agtgagtaag
    21721 gcgatcattt taatgctgtg tcttgccatt tttttctcca taaatttcaa aaggaaatca
    21781 tgcctgatgc gcattgcgac ggcgtgagta ccattcaagg atttggtgac gatgcaaact
    21841 gacggaacga ccaacgacaa caacaatgag aagcgcaccg gacaatgcgc tggaaatttg
    21901 attcggcact ccggccatct gtagcccctg ctgtaaaaat cccaccagca gcgccgccaa
    21961 cgcggacccc ataatcgacc cggagccgcc ataaatattg gcgcctccca gcacaaccgc
    22021 cgtaatggtc ggcatcagga aagaggcgcc cagatccgaa cgtgcggagc caaagtaaga
    22081 aaccagtaat acggcggcga tcgcggaggc gcatccggtc atggcataca cggtatacaa
    22141 cgtgcgattc accgggatcg cgctgtactg cgcgacacgg gcgctctggc caatcaggaa
    22201 aacgttgcgt cccatatgcg tgcgatgcat gagcagccag aaaaacagac agcacacaag
    22261 aaaaaaaata agcggcatag gaataccaag aaatgaaata ttggcaaagt cagtgaacgc
    22321 tgtgggaaat ccaccaatac cttcataacc cgtggcgcca gccataccag ataacaataa
    22381 tgcgctacca ccaaataaat acatggttcc cagggtaatc accaacgggt ttacgccggt
    22441 ataaataata agtccggcat ttatcagccc acatattgcg ccgagtagta gggtaataat
    22501 aatcgctaaa ggtagcggca taccgagctg aaacagcaca cccagggtaa tcgcgcatag
    22561 cccgattgta gaaccaaatg aaatatccat accaccgctg acaataacca ttgttagcgg
    22621 caaagcgaca ataccgatac aaataaaatc gctagtgcta aaaagtaaga cattaatatc
    22681 taataaacgt ggattaatca gaccgaaagc cagaatttca aagatcaata aggctgccag
    22741 cgcaatttcc cagctatagc gtcgccatgg attcatcatg ccacctcttt gtttttattc
    22801 tgttgtgcgt gcgtttttgc ttccgcctgt agtggagtgg gtggtgatat aaaacgggca
    22861 tatttctggc ggcgcagatt gcgttgtaat gcgcaacgca gccgcccatc gaataccagt
    22921 acgcccaaca ataccaggcc agcaataaaa tcgttccacc aggcggggat gcgcagcagc
    22981 actaacacac tatcgatttg cgtaagaaaa taagcgccga gaatagcgcc gatgaccgtg
    23041 cctgacccgc ctaacaggct aattcccccc aatacgcagg ccgcgatggc tttcatttcc
    23101 agccccgtgc cggtttgatt gggaatgaag ccaatctgcg aggcaaacac gattccagcc
    23161 aatgccgcca taccgccatt aagtgaaaat gccatgatgc gtaccatctc ggtacggaca
    23221 cccaattgcc gggcgccctg caggttatcg ccggtggcgt aaaaattgcg gccaaaggcg
    23281 gttttcgcca ggagccaggc cataagcagc gctaacacca gggtaaacca gccgattgcg
    23341 gaaattccca gaaacaccgg agcagagagt tgctttaagc ctgcgggtaa tccttcaatc
    23401 cattttcccc ctgtccatag cagcatgatc ccacgataca agcccagcgt tcccagcgtg
    23461 gcgacaatgg cgggtatctt caaccaggca accagtacgc cattaaaaaa tccggcgaca
    23521 attcctaata ttagtgtggc caggcaggcg accggcaggc tatagccggc gtttaacatt
    23581 actcccagca ataccgcgca cattcctgtc gtcgagccca ccgatacatc aatattgcgg
    23641 gtgagcatta ccatcgtcgc gccaatcgcc aacagcatca aaatttgcgc gctactgaaa
    23701 accattgtca gcgtttgcac gctcaaatac tggctatcca gcgcgccaag aaacacgaat
    23761 aaacagacta ttgccagcag tgccgtcgct tcccggttat tttggatgaa tttcaacatg
    23821 ttgcctccga cgcaccatgt tcgccaaacg caacgtgcat gatggtatca acgttaattt
    23881 cctcgccgca taacgcaggc ccccccagtt ccccctggtg catgacatat acgcgatcgg
    23941 ccatctgctc tatctcttcc agatcggagg aaataaacag caccgcgaca ttttgttgcg
    24001 cgatactgcg caacagctga taaatatcgc tgcgggcgga gacatcgaca ccgcgggtcg
    24061 gttcatcgac aatcagtaat tgcggagagg cctccaggca tttggcaatc aatacttttt
    24121 gctggttacc gccggataaa gtacgcgccg cctgttcggc attattgagt ttgatattta
    24181 acgcgcggtg gtaacgttca agggtggcgt tatcccgctg gggctttatc caaaatcctt
    24241 tttggttgtg ggtcagcgaa cagacattcc atgccaggga agcgtcaaga tacagcccgg
    24301 atgactgccg atcttccggc aaatagacca ggccgagctg caaccgctgt tgggttgtca
    24361 gggcgttaat ttcttcacca ttgaacagca tccgccccgc attgaccggt ctaataccgt
    24421 acagcgtttc agccaattct gtgcgtcccg cgccgaccaa cccggccaaa ccaaggattt
    24481 cgcctgcccg cacctcaagg ttgatattca taaaaccttc gcccgtcagt gactccagcg
    24541 ctaataccgt cgcgccgcgt tcgttctgcg ggcggctgcc aggcaattcc agccacaact
    24601 tttgactcgc ggaaagactg acgccctgcg ttgccggggt gatagcttga ataatctcgt
    24661 cggtagaaag gtcatgcgtt tttctgaata atgcgatttt accgtcacgc atcacgctaa
    24721 cgcagtgagc taactgtcta atttctggca gcttatgaga aataaataca attccgacac
    24781 cctttttcag caactcttgc agacgcgtaa ataaccggtc agtttcggct ggcgttaacg
    24841 acgccgtggg ctcatcaaga attaagattc gcgagtcgcg catcaagccg cgcataattt
    24901 caacgatctg gcggtctgca acatcaagcg tacccgcagc gctcgccgga tcgagttggc
    24961 atcccatcgc ctttaatagc tgctgcattt tttccgtgga ggcctgacgt ccctgcaagc
    25021 caaacaagat attttcccgc acagataaac tcggaaataa cagaggctcc tggggaacca
    25081 ggtaaatgcc atactggtgc gccttcagag gcgttaaatg actgcaacgc acaccagcaa
    25141 tatcgatagt ccctccatct ggcgggacta taccggcaat aatcttcatt aatgttgatt
    25201 tacccgcacc attgccgcca agcaatgcgt gcacctctcc cgcatgcaga gtaaagtcaa
    25261 ttccctttag tacttcgacg ccggaataac ttttataaat gttctgcaca caaatcagag
    25321 gggatgcagt attgtgactg atttgcatgt tgcctccgct ccctcaatgt tgactgacgg
    25381 gactgaacaa atgttttttg aaaaagaaat tgttcaaaac ggtagtagtt atttggtcaa
    25441 aaaactctca tccagatcac gttttctgaa taaatgaatt tttagatgat aaatgttcag
    25501 atttggcgcg tttttgtggc gttaatcacg gttatttcgg agtgataact gaacaattgt
    25561 gttaatgatt tagaaatgtt caaagtaaag ccaggttatg acaatgagcg ataatacgtt
    25621 ggtatctgat tatggaatgt gcgaagaaga gcaggtggcg cgtattgcct ggttctacta
    25681 tcacgatgga ttgacgcaga gtgaaatcag cgagcgtctg gggctaaccc ggctaaaggt
    25741 ttctcgtctg ctggagaaag ggcatcagtc cggtattatt cgcgtacaaa tcaactcccg
    25801 tttcgaaggg tgtcttgagt atgaaaatgc cttgcgtaac cacttcgcat tgcagaatat
    25861 ccgcgtgctg ccggcattac ccgatgccga tattggtctg cgcttaggaa tcggcgccgc
    25921 ccatatgttg atggagtcac tgcggccaca gcaactgctg gccgtcggct ttggcgaagc
    25981 cacgatgacc acattaaaac gcctcagcgg atttatctcg gcgcaacaaa tccgactggt
    26041 cacgttatcc ggcggcgtgg ggccgtatat gaccggaata ggccagcttg atgccgcttg
    26101 tagcgtaagt attatgcccg cgccgctgcg cgcatcatcg caggaaattg cctgcacgct
    26161 gcgcaatgaa aatagcgtgc gggatgtgat gctcacagcg caagctgccg atgccgccat
    26221 cgtggggatt ggggcaatta accagaaaga tcaagccagt atcttaaaat ccggctatat
    26281 cactcagggt gaacaactca tgattggccg caaaggcgca gtaggcgata ttctgggcta
    26341 tttttttgat gctcatggcg aaattattcc agacatcaaa atccataacg aattaattgg
    26401 cctgaagtta aattcacttt ccacgatccc aactgtgatt ggcgtcgccg gcggcgaaca
    26461 aaaagcagaa gctattattg ccgctatgcg cggtaactat atcaatgcgc tggttaccga
    26521 tcagaaaacc gcagggaaaa taattcaact tattgaaaaa taaaaaataa aataacactt
    26581 acctcaattc aataaacaat aactgacagg attttatgta acgatgtaaa aatagccgag
    26641 ggtaaaaaaa tggctcgact ctgtacccat actgaatcag gacattacct gatggctctt
    26701 gacgccggta ccggtagcgt cagagcagta atttttgatc tacaaggaaa gcaaatagct
    26761 gtcggtcaag cggaatggca gcatctggcc gtgccggatg tgcctggttc gatggagttt
    26821 gatcttgcca aaaactggca actggcttgc cagtgtatcc gtcaggcact acagaaagcc
    26881 gccatccctg caacggctat cgctgccgta tcggcctgtt cgatgcgtga aggcattgtt
    26941 atttatgaca gtaacggcga acccatttgg gcctgcgcta atgttgacgc ccgcgcggcg
    27001 cacgaagtca gtgaattaaa agagctgcac gataacacct ttgaggagga agtttatcgt
    27061 tgctccgggc aaacgctggc gctcagcgct attccgcgtc tgctctggct tgcccaccat
    27121 cgtccggata tttatcatcg cgcgtcaacc gtcactatga tcagcgactg gatggccttt
    27181 atgctcagcg gcgaactggc ggtcgatccc tccaacgcag gcacgacggg gttattggat
    27241 ctggtgaccc gcaactggaa acgtagtctg ttacagatgg cgggcctgcg ttctgacatt
    27301 ctctcgccgg taaaagaaac cgggacactg ctcggtcaca tttcacagaa agcggctgaa
    27361 cagtgcgacc tgcaagcggg tacgccggtc atcgttggcg gcggcgatgt gcagttaggc
    27421 tgtctggggc tgggcgtcgt acgcccggcg caaacggccg tgctgggcgg aaccttctgg
    27481 caacaggtcg tcaatcttcc cgcgccggtc accgacccaa acatgaacgt tcgcatcaat
    27541 cctcatgtga tccccggtat ggtacaaacc gagtctatta gcttttttac tgggttaacg
    27601 atgcgttggt tccgcgacgc cttttgcgcc gaggaaaaac taatcgctga aaggttaggt
    27661 attgatgcgt attccctgct ggaagatatg gccagccggg tgcctcccgg cgcgcacggt
    27721 gtgatgccca tcttctctga cgttatgcgt tttaaacgct ggtaccatgc cgcgccgtcg
    27781 tttatcaatc tgtctatcga tcctgaaaaa tgtaataaag cgaccctatt tcgcgcgctg
    27841 gaagagaatg ccgccattgt ttccgcctgc aatttacagc aaattgccgc gttttccggc
    27901 gtacaggccg actcgctggt ttttgccggc ggaggatcta aaggcaaatt atggagccaa
    27961 atccttgccg acgttacggg actcaccgtt cacgtacctg tcgtcaaaga agctaccgcg
    28021 ctagggtgcg ctattgccgc aggcgttggc gtgggtatct ggccatcgct ggcggaaacg
    28081 ggagaaaagc tagtgcgctg ggatcgggag cataaaccta atcctgaaaa tttcgctgtc
    28141 tatcagcagg ccagagaaaa atggcaggcc gtttatcagg atcaacgcgc gctggtcgat
    28201 ggtggcttaa cgacatccct ctggaaagcg ccaggcctgt aacaggagaa taagcatgca
    28261 aaaaacgaat gagaagaatc atgaataccg ctttagtgat aatggcccta aatacttaat
    28321 ccgtgggccg ggctgcgata tgggcgtcgt catactacaa ccagggcagt cattccctaa
    28381 ccatcgccat aataccgctt gtgaggtttt ttatacccta agcggtgaag tgtgcctgta
    28441 tctggaagga acacctcata tcctgcaaac tggagatgtt ttacagtgcg aaccagggga
    28501 ggcacattat ctcattaata acggcgataa gccctagaaa ggcgtgttta ttaaatcgcc
    28561 gcatctggaa aatgacagcc accccgcaga tccaccggcc tggtaacgcc cacgccatcg
    28621 ccagattttg ccggatagcg ccacgagagc cttgtccggc ctccaaacgg cattcgttaa
    28681 tgcaatatca agctgtcatt tgatgacctg ttggttcaag atatcacact gatgatcctg
    28741 aatttcctcg gcagaagcgc gattgaaggt cagtaaatta cgctcggtcg ccagcaggac
    28801 aaaagagcca tcgctttggc gtaccaccgc cagcgcgcta catcactgca tccccgcccg
    28861 cgcaggaact ttccctggtc ccatcgccac cacagcagca aaaaatagca gtgcggtcat
    28921 aaactccggc agtagcgaag tcgcccacag aaggatagta atgccaacga tgatggaagg
    28981 gaggatcaga ggataggaca accagagcga catacctgtc tcctgacgat tttttcagca
    29041 agaatacgac ggacagtcag gcaggtaaac gccagatata gtggggttat cgcaggatta
    29101 agtggacaga tcagtgataa tgaatttcac caaagtattc agacagcacg taatagcggc
    29161 aatactcaaa agggctgtcc ttcccggcct gaaacgtctg tctggcgacg gataacagcg
    29221 gtttattggg ggcgatttgc aatttttcgc acaggtcagc ggaaggtaaa atcgcctcaa
    29281 ctttttctat cgccgagtcg cttgtgacgt ttaataacga ataaagcgac gtatgctcca
    29341 gcgcctgcgg tgtgagttgc agatcgggaa agaagctaag atcgagatag atcttttcat
    29401 ggttaaacgg acggttattc aggcaacgaa tacgcgaaat atagagatag tgatgctgtg
    29461 cgggcaggct caagccgtct gcctgagcgt cgcgcgcgcg gcgcggcgcg atttccagaa
    29521 tacggttctc aatcgccacg ctggcgtcct ggagatcgcg ggtaataccg cgaaacgtgt
    29581 gcccgtagct cacgccttcc ggcaccgagc acaccaccga accactcccg cgctgcgacg
    29641 aaataatgcc cgcattgatt aattcgctcc aggcctgttt aaccacaatc agcgagacgt
    29701 tgtaggatct ggcaatctct ttttgcgtcg gtagttggct acccaaaggc aaagacccgt
    29761 tctggatctg ctgacagatg ataaaaaata gttgcttata aagcggagta aagctcgttt
    29821 tatcaacctg caagctgcgc acctcacgtc ttcgccagca ggggacgttt taccgtcccc
    29881 ggcagggtga agtcgctacc ctgcgatttg cctggccagt tctgccaaat cgaaatgatt
    29941 catacgatcc aaagtcgtta aataatcggc gggaaaagcc tccacgccat ggaatgcgcc
    30001 ggaaatcgcc ccgaccatgg tggcgacagt atcagtatca ttgccgatat taacgccgga
    30061 gataatagca tctacggcag aattcggaca acacgcgaac aggccaaagg ccgcgggcac
    30121 cgcttcactc acgtgcagcc cggagccaat aatatcggca atatccacta tcgccgtttc
    30181 ccaatggcga tgacgtttac cgatatctac ggccagctca atgcgtcggg caacggaagg
    30241 acctgccacc atcatcgccc cttgctcctg cgccagcaga tagccccttt gcgcaccgta
    30301 aataccggcg gcaataatgc tgtctgcatt ggtctgcgct cttaacgcct cgctggttgc
    30361 cgccgccatc gccgctgcgc cggacatcgc cagcacgtta ttatgcgtaa aacggcaaat
    30421 ctgcagcgcg cagtcaatcg ccgcgtcaat atcacccggg tgcagcaccg ccgctggcca
    30481 aatcttcatg gcggcgccgt tcgttgcctc cgcattaccc ttattaatga tctgtaccga
    30541 ctgtttctcg ccttccagct caccctgtaa agaggcgcgg ttatcattga atattgcctt
    30601 cattgccgca cgcgtcgtcg ggccggtaaa gttggcgtag tacgggtaat ccagccactg
    30661 ctggaaagct tcgcgcatcg cttcgtcgct gacttcacgc tgatggcgca gcagcgcatc
    30721 catgatgtac ttcgcctgaa taaaatcatc cgtgcacatc cccgcttcat tgcagcgccc
    30781 aaacgtgtcc gcaggcggtt tttgaaaggt cgtcacccag ccgccaaaat agtcttttat
    30841 ttgctgctgg gtgcgtactt ccgtcgcggc tcccatcgcg tccgcggcgg cggcgcccac
    30901 caggcatccc agtattttgt tttgatcaac gtgcatgatg actccttatt tcacggtcat
    30961 ggcttgtgcc agcgaatggc tggacagaaa agtgtttagc tggtcgggaa acggcagagc
    31021 ggtcattgcg ccttttgccg tcaccgccat agcgccgcag gcattggcat tgctgatggc
    31081 ttccgccagc agggcatgat cccagcaatt tgcgcgggaa agggtgaaca gcaggccgcc
    31141 gacaaaagca tcgcctgctc cggtggtatc gacgacatcg acgcgtggtg cgggaaaatg
    31201 gaactccccc tcggcggtaa tcaacagcgc gccatcggcc cccagcgaaa tgatcgtggt
    31261 gtcacagcct agatcgcgca ggtaataacg cgcatcctgc cagtgactgg ccccgctgag
    31321 ctggcacagc tcatctgccg agactttgca gatagaagcc aacgcggcgg accgggcgat
    31381 cagttcaggg atttcatcgg tattgcgcca catcttgctg cgtaagttga cgtcgaataa
    31441 cacgtagcca ccggcttctc gcatgcgtct cgccccttcc agacatgctt cgcgagcggg
    31501 actgtcggtg aggccaattg agctgaagta aaaccattcg tgctgcctga acggcggcaa
    31561 atcctgcggc gaaacgtagg tatcagcccc cggatgcacc agataggtaa agctgcgttc
    31621 cccgtcagcc gtcaggttga cgatcagcac cgcgctggtc agggccgcat ccagccgcag
    31681 cgaagagaca tccacgccgt tatcctgaaa aacctggcgc aggaaacgac cggcgtcatc
    31741 atcaccaaga caaccgataa aaccgcactc cccgcccagc ctggcaacgc atacccccac
    31801 gttcgccgac gctccgccgg ggcatttcag atagctgttc tgtttttccg gcaccagatc
    31861 aacggaggca tcgccgataa cccaaacctt attcatggcc ttcatttgcg cctccttatg
    31921 cctgtttctg cgccagggcg agctgaatat cacgataata ttcattatta atcagatact
    31981 ttttcatcag cagcccaacc gcaaggtgga acagagccgg aatgagcgtc atcatcagcg
    32041 caataccggt gagcgaacgc gcgctctgtt caacatcggc ctgatagcca aagtggctca
    32101 gcaggaatcc gagtatcccg cccgcgatcc ccatcccaaa cttctggaag aagaggatgc
    32161 cgccaaacgc caacccggaa acgcgcagac cggttttctt ttctccgtaa tccaccgctt
    32221 cggcgataga ggaccagaac accggcattt acatatcgca gaagaaatta ataagaaaat
    32281 agaacgcaaa cgccaggata agattttcac gcccgacaga gaaatacatc agcgcgctca
    32341 ggataaaggt aataatctgg gtgtagcgga acatcttaat tttgtcccag aacttggtta
    32401 tccaggtggt ggcaatcatc gctaaaatag aggcaacgac gccggtagtc aggaagggtg
    32461 aaatcaggct atctccgccg ttcagataat acttggcgta ataagcggca acggaaccgc
    32521 gaataacata accgcacatc agcagcagaa taacaacgcc gagaataatc cactgatcgt
    32581 tacgtaacag atatttaaac tgtttcccca ccgatagcga ggtaatctcc ggctcgctgc
    32641 gttcacgcgt ggtgagaaaa cagaagataa acagcagcgc acccattgcc cccattaagc
    32701 ccatcgaaaa ctgatagccc aaagccttat taccctgccc cagccagacg gcaagcatcg
    32761 gtacaacgat agtcaccaga aaagcggcaa tcttggtcat cacaaagcga taaccgttgg
    32821 cgcttaaccg ctcaacgggg tcgctggtaa tgacgccaat catcgaaata taaggaatgg
    32881 tgatcgcggt atagaccagg gtcataagaa tataggtgcc ataggcccac gctagcttgg
    32941 ccatataagc catgtcaggc gtaataaaca tcaaatacac ggcgaaacca aaaggaatgg
    33001 caaaccacag cagccacggg cggtaacgtc cccagcgcgt gttcagttta tcggtcagaa
    33061 cccccatggc cggatcgata atggcatcaa tcatccgcac aaccacaaac agtacgccaa
    33121 catcagcggc gctcaggccg tagatatcgg tatagaaata ggcgaggagc agctgcatgg
    33181 cgataatcac aacgtttatc gccatatctc ccgcgccgaa gccgattttt tccacgatag
    33241 aaagtttcat gttgatattc ctttacgctt aacagcgcaa atctggtgaa caattaatga
    33301 tgtcactaca tgaaataaaa acgtttttat atataagcca tccatcagac aatctatgga
    33361 ggctatgaag agagtgtaac gaaccaccaa aagatataaa ggtatacctt tatatctttt
    33421 ggtcggtttc acatattttt atagacacga tcttacccca gttttaaacc gggataagaa
    33481 tcaataagat aatgagcagg ggggtgtaac gaaaatcagc gggaagacaa aatggcgcaa
    33541 ctatggtcct gaatctcttc cgccgatgcg cgattaagcg tcagcaggtt acgctcggtc
    33601 gccagcagaa caaaagagtc gtcgctttgg cgtaccaccg ccagcgcata gcgtcccata
    33661 tgatcgcgcg cttccggcac ctcttccgcc agcatcataa acggactacg ctgcgccagt
    33721 tcgctctcgg ttacccggcg cgccaggtat tcatgcccca tcagatcgcc cggcagcgga
    33781 agccagcgag tgctgatgcg cgtgagatcg ttatccagtt gttcccgaac gtcaggacgg
    33841 atgcaagaaa tatggatatg caaatggtcc tgtgaacgac caagccgcga attaatcgcc
    33901 agcgagaccg cgctatccgg aatatcatgc ccgtattttt tactcatata gccgcgagcc
    33961 tgccaggcca gccagaaaaa gttgggcgta gcgggttcca gcaatagcgg gctttctgta
    34021 ccgttgatac ggtaggtggg catcaataaa tattgcaacg gaccgtgacg atctttaaag
    34081 atgacatagc cggcgcgagg tttgacttcc gcgcaaggcg ctgggttttg atgctgtaac
    34141 tgatcgggca ggcaccgttc aagcacgatt tcccgtaatg catcaggatt gccggaaaat
    34201 ttccagtaac cgacgcccgc cgcggcgaca atcactatca ccgccagtaa aaagtagcct
    34261 gtttttttca tgatatgcgt tccctgtgac ccatagacgg ggaagagtaa cgcaaaattg
    34321 tggcaaagaa aaaacccggt aacataatac gttaccgggt ttataaacgg tttagcgttt
    34381 gctgatttgg tcgaacgtac cgccattagc aaagtgatct ttttgcgcct tcacccagcc
    34441 gccaaacacc tcgtcaatgg tgaatagctt cagcttcgga aacgcatcgt cgtatttttt
    34501 cgccacgtca gcatcgcgcg gacggtagaa gtttttcgct gctatctcct gcccttccgg
    34561 cgaatagaga tacttgagat acgcctccgc caccgcattc gtccctttct tctcaacgac
    34621 tttatccacc acggacacgg tcggctctgc gaggatagat tcactcgggg tcactatctc
    34681 gaatttatct ttacccagtt cgttcgtcgc cagcagcgct tcgttttccc aggcgatcag
    34741 cacatcaccg ataccgcgtt caacgaaagt attggttgag ccacgcgcac cggagtccag
    34801 cacttcaacg tttttaaaca gggctttgac aaagtcctgg gctttggcct gatcgttatt
    34861 gttgtggtgc agggcgtagc cccatgccgc cagatagttc cagcgtgcgc cgccggagct
    34921 tttcgggttt ggcgtaatca ccgacacacc gggtttaatc agatcgttcc agtcatgaat
    34981 ttgttttgga ttgcctttgc ggaccaggaa aacaatggtg gaggtgtaag gtgctgagtt
    35041 atccggcaga cgcttgatcc agtttttatc gatacgacca cgttcagcaa tagcgtccac
    35101 atcgtaagcc agcgccagcg tcacgacatc ggcttcaatg ccgttaatga cggaagtcgc
    35161 ctgtttacct gaaccgccgt gcgactggcg gatcacgacg ttgtcgccgg tttcctgctt
    35221 ccagtgcgcg ctaaacgctt tgttgtactg ctcgtacagc tcacgcgttg gatcgtacga
    35281 tacgttaagt aactgaatat cctttgccag aatgctggtt gacgccagca ataatgtgaa
    35341 ccccacgccc cactttttca tcgcccgact cgcttatgtt gtgttgtgat gagcaaagcg
    35401 tgccagaaag agatccaaac attaaagaat aaaaaaagat tggctataac ttcgaggaat
    35461 aaatctgagg gattgccgga tggcggctag cgcctaatcc ggcctacacg tttctgcaac
    35521 ctgtaggcct gataagcgta gcgccatcag gcgcgcaaaa acaatcagta cagttttttc
    35581 gcgcactcca tccagtcgct tttgaacgga cgcttcatgt tttcaatcgc atcgatgatg
    35641 tcatgatgaa caagctgctc gttctggata ccgacacaac gaccgccatg gccttccagc
    35701 agcaggtcaa tagcatacgc gcccatacgg gaagccagaa tgcgatcgta aggtaccggg
    35761 gaaccaccgc gctgaatgtg gccgagcacc gtcgcacgcg tttcacggcc cgtttctttt
    35821 tcaataaagt gcgccagttc gtcaacatcg cacatatgct cagtaatagc gacgatagcg
    35881 tgttttttcc ctttcgcgat cccggctttg atttcggcca ccagatcttc gcgattaaat
    35941 tcaacttccg gcaccacgat aaactcacag ccgccagcaa tagccgccgc caacgtcagg
    36001 tcgccgcaat aacggcccat cacctcaacg atagagatac gctggtgaga agaggaggtg
    36061 tcacgcagac ggtcaatcgc ttccactaca gtgccgagag cagtgaagta gccgatagtg
    36121 tagtcggtgc ctttgatgtc gttatcgata gtgcctggca gaccgatgca cgggaagccc
    36181 atttcagtca gacgttttgc acccatataa gaaccgtcgc cgccaataac taccagcgca
    36241 tcgataccgc gttttttcag gttttcgatc gcgacagcgc gaatattttc gtcacggaat
    36301 tccgggaaac gggcggaacc gaggaaagta ccgccacggt tgatcatgtc agatacgctg
    36361 taacggtcaa gctgaaccat acgatcttca tacaggccca gatagccgtc ataaatgccc
    36421 atgacttcca gcccttccgt caacgctgcg cgcacaacac cgcggattgc cgcgttcatg
    36481 cccggcgcat caccgccgct tgtcaacaca ccgattttct taatcatgac tacctctgaa
    36541 ctttggaatg caaaatgaaa tctattgccg gaagccgatt tcgcacttcg aaacgatcca
    36601 acgaatatac agatagtata acaatccctt cctgctgaat tgattcaggt caggccaaat
    36661 ggcggtaatt tatacacaaa atgctggcct ggctcacttt ttaacaatca attatacaag
    36721 ctcgaacttc ctgccttccc tggggacgac tgaacaggga tcctgatgaa taatgacatc
    36781 tgaacccgga aaacgccgca aaatcgcctg ctctacctgg tcagccacaa aatgcgcctg
    36841 aacgagcggc agattatctt ccatttccaa atgaatctga ataaagcgag tcggccctga
    36901 ctgccgcgtg cggagatcgt gcgcgccgct gactcccggc catgacgtca cgatatcaat
    36961 aatttcctgt cgttccgcat cgggcagcgc gcgatccaat aatgactgca ccgcctcata
    37021 ccccatacgt aacgcgctat acaaaatata gatgccgata cctaacgcaa acagggcatc
    37081 cgcacgatgc caaccgtacc aggataaccc cagcgcgata agaatcgctc cgttcatcat
    37141 aacatcagac tgataatgaa gcatatccgc ccgtaccgcc tgactttggg tcttgcgtac
    37201 cacccagcgc tgaaacgtga ccagtataat agtgcatatc agagcgatga cggtaacgcc
    37261 aatccccacg ccggggtcgt tcattggcgt cggcttaatc agattctgga tactggtcaa
    37321 aaacaacgcc gaaccggaaa taaacatact ttgcgccagc gccgccagcg actccgcttt
    37381 accgtgacca aacgtatgtt catcatctgc gggttgcagc gaataacgca cgaccaacaa
    37441 attcgtcaat gacgcggcaa tatccaccag cgagtccacc aacgccgcca gaatactcac
    37501 cgatcccgta taccaccacg caaaaatttt gatcaaaagt aacgctgatg ccatcgccgt
    37561 tgccgcgata gccgcccggc taaccagccg tccataggtt tgattcataa atactcccgc
    37621 tatcttctgc cggtagtata acggatggtt taaaacagta agctaataac agaatgacaa
    37681 actggagata aaaaaaaccc ccacatcatg tgggggaaga cagggatggt gtctatggca
    37741 aggaaaacag ggttgttact gggaacgtga gttgctacta ctcaataatt tcaacgatga
    37801 acttttttgc cattgcgcca cgtcgcgcag ttgctccatt cgttgctgat gcttttcatt
    37861 caaaaccgct tgctgctccg gcgttaacag gcgatacatc tggttacgca cgcgggccat
    37921 ttcgacctgg cgggcaacct gctcttgcgc cattttttct gcctgagcgc gcacaacgct
    37981 ttcatcaaat ttttctgcgg tgacaagccg atgcattgtc tccatttcgc taacattaac
    38041 aggaggctgt tcgtgccttg cctgctgcat aagatctcgc atctgctgac gctgatgttc
    38101 ggttaaactt atgccgtcaa acatatgatt ttgcgcgcta cgctgcgtgg ccccgtcacc
    38161 ggggtgccag ttatcgcttg taacaacttc agctgcgtgg cttaaaaaac tgaatgccag
    38221 cgttgaggcc ataacagcag cggtaacttt gcgcatcgct tgctcccaaa atcttttctg
    38281 tcgcgattca acgagagaca gtttacgatt cgggctgcaa acatgcgtca gggggtgtaa
    38341 aacaacgtaa agtcatggat tagcgacgcc tgatgacgta atttctgcct cggaggtacg
    38401 taaacaatga ataaaatcct gttagttgat gatgaccgag agctgacttc cctgttaaaa
    38461 gagctcctcg aaatggaagg ttttaatgtc ctggtggccc acgacggcga gcaggcgctt
    38521 gagcttttgg atgacagcat cgatttactt ttgcttgacg tcatgatgcc gaagaaaaac
    38581 ggtatcgata cgttgaaagc gcttcgccag acacaccaga cgcctgtcat tatgctgacc
    38641 gcgcgcggca acgagctgga tcgcgttctc ggccttgagc tgggcgcgga cgactatttg
    38701 cccaaaccgt ttaacgaccg cgagctggta gcgcgcatca gggctatttt gcgccgttcc
    38761 cactggagcg agcagcagca gagcagcgac aacggctcgc cgacgctgga agttgatgcg
    38821 ctaagcctta atccgggtcg ccaggaagcc agtttcgatg gccaaacgct ggagctgacc
    38881 ggtacggaat tcaccctgct ctatttactg gcgcaacacc tcggccaggt ggtttcccgt
    38941 gaacatttaa gtcaggaagt gctgggtaag cgcctgacgc cgttcgatcg cgccattgat
    39001 atgcatattt ctaacctgcg ccgcaaactg ccggaacgca aagacggtca cccgtggttt
    39061 aaaacattgc gtggtcgcgg ctatctgatg gtttccgctt catgatagga agtttaaccg
    39121 cgcgcatctt cgccatcttc tggttgacgc tggcgctggt gctaatgctg gtactgatgt
    39181 tgcccaagct cgattcacgc cagatgaccg agctgctgga cagcgaacag cgccagggat
    39241 tgatgataga gcaacatgta gaagctgaac ttgcgaacga tccgcccaac gacctgatgt
    39301 ggtggcgtcg cctgttccgc gcgatcgata agtgggcgcc gcctggacag cggttattac
    39361 tggtgacctc tgaaggacgc gtgatcggtg ctgaacgcag cgaaatgcag atcattcgta
    39421 acttcattgg tcaggcggat aacgccgatc atccgcagaa gaaaaaatat ggccgcgtag
    39481 agatggtggg gccgttctcc gttcgcgacg gagaggataa ttaccagctt tacctgattc
    39541 gaccggccag cagttcgcaa tccgatttta ttaatctgct gtttgaccgc ccgcttctgt
    39601 tgctcattgt cacgatgctg gtcagttcgc cgctcttgct atggctggca tggagtctgg
    39661 cgaaaccggc gcgtaagttg aaaaacgcgg ctgatgaagt ggcgcaaggc aacctgcgtc
    39721 agcatccgga gctggaggcg ggtccgcagg agttcctcgc cgctggcgcc agttttaacc
    39781 agatggtgac ggcgctggaa cggatgatga cctcgcagca gcgtttgctg tcagacatct
    39841 cccatgagct gcgaacgccc cttacgcgcc tgcaactggg taccgcgctg ctgcgtcgtc
    39901 gtggcggcga aagcaaagag ctggagcgta ttgaaaccga agcgcagcgt ctggacagca
    39961 tgatcaatga cctgctggtg atgtcgcgta accaacagaa aaatgcgctg gtcagcgaaa
    40021 cgatgaaagc caatcagcta tggggcgaag tgctggataa cgccgccttt gaagccgaac
    40081 agatgggcaa gtcgttaacg gtaaattatc cgccggggcc gtggccgctc tatggcaacc
    40141 caaacgcact ggaaagcgcg ctggaaaata ttgttcgtaa tgcgctgcgc tattcacata
    40201 cgaagattga agtcggcttc tcggtggata aagacggtat tacgatcacg gtcgatgacg
    40261 acggaccggg cgtaagccct gaagaccgcg agcagatctt ccgtccgttc tatcgcactg
    40321 atgaggcgcg cgaccgcgag tctggcggca ccgggctggg gctggcgatt gtcgaaagcg
    40381 ccatgcagca gcaccgcggc tgggtgaagg ctgacgatag cccgctgggt gggttgcggc
    40441 tcacgctgtg gctaccgctg tacaagcgaa cctaaaaacc atcggcctgc gaatgcaggc
    40501 cgatttttta tctcgccgtc gagatttacc gggaaatgtc tggcgctaaa atccactcgg
    40561 cgctgtcgtt ccacacgtcc atccgggtaa ttttgccatc gcgcacttcg aaacgatcga
    40621 taaagcggtt atcggcaaac gggcgaccgt cgggccattc gccatacaac gtaccgttgg
    40681 aataaatcac aacgtaatca tcatgctgca ccgcatcaaa cttgcccagc gccttcttca
    40741 cccacttgta gcgagcgccg ttaaactgcg cgatatctgc cgcgcccgcc atcgcccggc
    40801 ctccggtgaa ggtaattttc acctccgggt gcatatacgt tgcggcgcgt tcagcatcgg
    40861 gaatcatcga ggccaccaaa aattctttta cgatcgccac cgcattttca gcttcagtca
    40921 taatccttcc tttcattttg gcggagtttt atccccccac agtcgtctgg cgctatcttc
    40981 aattttgccg ctcaaacgac gcttctgcat ggtgcggctc cagctcgccg acagcccggc
    41041 ggcgctcagc agccggtgat attgttcgtc atcaaacggc atagaccagg cgataacacc
    41101 cgcttcatga accgagacat cgctcagacg cgacgccagt tccagcggcg catcgctgga
    41161 gaccttacct ggcgcaatga cccgatacaa ccagccagtt tttccgctgt tctgcataag
    41221 gagggccatg tcgctgatgg caaagtggaa attaagttta aagcatggag agcgcggctg
    41281 agtgacctgg atcaacgcct cgccccagcg gtagatgtcg ccaataaaca cgttgtgttc
    41341 ggtcattccg tccgtcgaca gattctcgcc aaacgccggg gcgcaaaaca gcgtcgcctg
    41401 ctcggggaac tggcgaatcc aatcagcata gtgttcgcgg gggtaatgac atagcgcgcg
    41461 gtcggggccg ccgtggattt tcttttcggc ctgctgatcg cctgccagac ccagctcggt
    41521 cagcatgagt tcgccgtcga tttgcacctt ggcgatagcg ctcgggcggc tgccgtcata
    41581 gtcacgaatt ttgccaataa acacgtcaac cggataatgc atctgctgct ccttacgcgg
    41641 atacaaaaaa agcgagtcat cagactcgct tctacagacg tgcaatgcaa attatttttt
    41701 agcggcgaaa cgcgctgctg cttcgtccca gttcaccacg ttccagaact ctttgatgta
    41761 gtccgggcgg cggttctgga atttcagata gtaagcgtgt tcccacacgt ccagacccag
    41821 gatcgggaag ccggaagcgc cggaaatggc ttcacccatc agcggggaat cctggtttgc
    41881 ggtagaaacc acagccagtt tgtcgccttt cagcaccagc cacgcccagc cggagccgaa
    41941 acgggttgct gctgcttttt cgaattcagc tttgaagttg tcaacggaac cgaagtcacg
    42001 ctcgatagcc gctttcagat cgccctgcag agtggtgcct tttttcagcc ctttccagaa
    42061 caggctgtgg ttagcgtggc cgcccgcgtt gttacgcagc acggtttttt tgtccgctgg
    42121 cacctggtcc agtttagtaa tcagttcttc aaccggcagg tcagcaaact caggcagatt
    42181 ttccagcgcc gcgttagcgt tgttgacata ggtttgatgg tgtttggtgt ggtgaatctc
    42241 catcgtctgc ttatcgaagt gcggttccag tgcatcataa gcgtacggca gggatggcag
    42301 tgtataactc ataatcatct ccattattgt cgagcggcac agtgttaacg ccgcgtaagc
    42361 agttggttca ttatagttaa ttaaatgata ttgaaaatga ttatcaatgc cgtacttttt
    42421 ccagggttat aaacgttacg gcatccgctg aaaaaaaccg atttttacgc ctccaaccga
    42481 aaccgcctgt tgatgaattc ctggaaatca tgaaatgtga aacagggttt caaaatcttt
    42541 cttttggtgc caatttttat cagcggtggc aaaatcaaga aggttataat ttcaccatgc
    42601 aattacattc ccggtaaatt attacaattg cgagggaatt atgaagcaac ctggttttat
    42661 acgtctggct acgttggcct tactctccac actctctttc ttctcccacg gcgaaaccat
    42721 tttgcgcctg gcctacgctg aaaatagcca gccggtaaaa gatgcgttgc acttcctggg
    42781 gcagcaagtt gaagagaaaa cgggcggcga tatcaaagta cagtacttcc cggacggaca
    42841 gcttggcggc gagcgcgaac tggtggagtt gacgcaggtc ggcgtcgtcg acatcactaa
    42901 agtgtcgtcc gggctgatgg agagtttttc gcctgagtac ggcgtgttct cacttcccta
    42961 cctgtttgcc accgtcgatg aatactaccg cgtaatggat aacccacagg tgaggagcct
    43021 gtttatcagt ccaccgccgc acagggtttt gtcggcgtag gctggtatga ttccggcgcg
    43081 cgtaattttt atatgagcaa agcgccggtt aaacgcattg aggatttacg cgggaagaag
    43141 atccgcgtca tgcagagtga gacggcgatc caaactctca aactgctggg cgcttcgccc
    43201 atcgccatga gccaggcgga ggtctatacc tcgttacaac aaggcattct cgacggcgcg
    43261 gaaaacaatg agttcgctct caccatcgcc cgccacggcg aagtcgcccg ttattacacc
    43321 tacgatatgc acacccgcat tcccgatatc ctgctaatga gtaccctcac gctggaaaag
    43381 ctgacgccgg aacagcagcg catcgtcgaa gccgccatca aggcgtcgat cgaatttgag
    43441 aaagccgcat gggacaagga aatagagaaa accaggctgg cggcggtaaa agatttcaac
    43501 gttgaattct acgagatcga caaaaaaccc ttccagaagg cagtacagcc tatttacgac
    43561 ggtctgaaaa acaaaccgcg gctttacggg ctgtatcaac gtatccagac agcaaaaaat
    43621 taatctaatc aggaaattaa gatgaacaca ttcagaaaag gacttgattt attgctgggc
    43681 gctatctgtt gcctggtgct ggcgataatg gttggcatcg cctgctggca ggtggtgagc
    43741 cgctacattc tgggcgttcc cagcaccctt accgaagaga tgctgcgatt tctcctggtg
    43801 tgggtatcaa tgctgggcat ggcttttgtc gccggtcaga aacagcatat cagtctgact
    43861 atcttactgg ataaggtgtc gccgacgatt cgcggctggt gggatatcat cctgcaggtc
    43921 atttttatcg cgttttccat ttgggtattg attatcggcg gcttaaagat ttctgcgatt
    43981 tctatgctgc aaatctcccc tgcgctgggc attccgatgg ggaaaattta ttacgcgctc
    44041 ccctgcgcgg gcatactgat catcctctat gggctactga atatcgttga cgccctgaaa
    44101 gctatccatt ccgccacgga taccactgag cacactctgg agaaatcaca tgattgaccc
    44161 tatttttgcg tcctgtacgc taattgccgt ctttgttgtt ttactggcca tgggcgcgcc
    44221 tatcgggatc tgcatcgtta tcgcctcttt cagcaccatg atgctggtac tgcctttcga
    44281 tatttcgatg ttcgccaccg cgcaaaaaat gttctccagc ctggacagtt ttgccttgct
    44341 ggccgtgccg ttcttcgttt tgtccggggt gatcatgaat agcgggggaa ttgccgcccg
    44401 actggtcaat tttgccaaac tgtttactgg caaactgccc ggctcgctct cttacaccaa
    44461 catcgtcggc aatatgatgt tcggtgcaat ttccggatcg gcgattgccg cctcaacctc
    44521 tatcggcggc gtgatggtgc cgatgagcgc gcgcgaaggt tacgatcgcg gttttgcggc
    44581 cgcggtgaat atcgcctccg cgccgacggg aatgttaatt ccgcccacca cggcttttat
    44641 cctttatgcg ctggcaagcg ggggaacatc gattgccgct ctgttcgccg gcggtctggt
    44701 cgcgggagtg ctgtggggcg ttggctgtat gctggtcacg ctggtggtcg ctaagcgtcg
    44761 aaattatcgg gttttcttca ccgtccaaaa aggcatggcg ctaaaagttg ccgttgaggc
    44821 cattcccagc ctgttactga tcgtgattat tgtcggcggc attgtgcagg ggattttcac
    44881 cgccattgaa gcctccgcga ttgccgtggt gtatacgtta ttgctgacga tagtgtttta
    44941 ccgcacgctg aaaattaagg atttgccttc gattttgctc cagacagtgg taatgaccgg
    45001 ggtcatcatg ttcctgctgg caacctcttc ggcgatgtcc ttctcgatgt cgatcaccaa
    45061 tattcctgcg gcgctgagcg atatgatcct cggtatttcc gccaataaac tggttatcct
    45121 gttagtcatt accgtctttt tgttgattat cggcgcattt atggatatcg gtccggccat
    45181 tctgattttt accccgattc tgctgccgat tatgactaaa ctgggcgtcg atccggtgca
    45241 tttcggcatt atcatgatct ataacctggc gataggcacc attacgccgc cagttggcag
    45301 tggtttatat gtcggggcga gcgtcggtaa ggtcaaagtt gaggacgtta tcaaaccgtt
    45361 gatgcctttt tacggcgcga ttatcggcgt tctgttatta attacctaca ttccggaaat
    45421 cacactgttt ttaccccgtc tactgggcat catgtaaggc atagtttcct gcacatctcg
    45481 ttgccggatg gcgattcgcg tcttatccgg ccaacgcgcg ataataatta tccgcaggtc
    45541 atcaccaggt aaaaaaaccg gctacctata aagtagccgg aaaagggaat aaataataaa
    45601 cagggataat gattagaatg tgtagcctat acccacgcgg aaacgggttt gtctttcatc
    45661 gctgttgcta ttgacggaaa cattacctac ctcaacgaat ggcgaccatt ggtcaataat
    45721 ataggcagtt ctgaagttat attcatagtt atctttgccg ccatcgtaaa gatcatattt
    45781 atcggctttc ttataaattc cttcgattgt ccagtcaaag ttgttccatt tataacccgc
    45841 ccagacatcc atacgattga tggtatcatc atcacggata tcagaagaac ggcgtacata
    45901 ttcaaaacga tagcgcgcgc caacccacca actttcattt aatgtccacg tcgcgcggaa
    45961 gtaaggctta taggtagagt aaccgttgcc tgtttccagc acaaaacccg gttgccaggc
    46021 gacatcaccg gttttaaatt ggtagcttat cgtatattcg ttaccctgtg tttccaggtc
    46081 attaaacgct ttattggtgt catccccgcc tgattttgag atagcttcta tcgcaaaacc
    46141 aacaccattc gcaaaccgat gagaaatata cgcacggtca tagttagctt tactgtcatc
    46201 aagatattca tgacga
//
LOCUS       DAJVKX010000022        45174 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000022 DAJVKX010000000
VERSION     DAJVKX010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 45174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45174
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.022"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            448..1662
                     /gene="alaA"
                     /locus_tag="OPY25_001197"
     CDS             448..1662
                     /gene="alaA"
                     /locus_tag="OPY25_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HCS0926851.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVNIAREHNLIIFADEIYDKILYDDA
                     EHHSIAALAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFILPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPRIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPREDDLEMAI
                     NRFGRFLSGYHQ"
     gene            1756..2355
                     /gene="yfbR"
                     /locus_tag="OPY25_001198"
     CDS             1756..2355
                     /gene="yfbR"
                     /locus_tag="OPY25_001198"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HCS0926852.1"
                     /translation="MKQSHFFAHLSRMKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGQLNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMAPDELHDIFAPLIDENAWSKEEQAIVKQADALCAYLKCLEELSAGNNEFRLAK
                     TRLEKTLELRRSQEMDYFMAVFVPSFHLSLDEISQDSPL"
     gene            complement(2447..4273)
                     /locus_tag="OPY25_001199"
     CDS             complement(2447..4273)
                     /locus_tag="OPY25_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HCS0926853.1"
                     /translation="MNGELIWVLSLLAIAVVLFATGKVRMDAVALFVIVAFVLSGTLT
                     LSEAFSGFSDPNVILIAALFIIGDGLVRTGVATVVGTWLVKMAGSSEIKMLVLLMITV
                     AGLGAFMSSTGVVAIFIPVVLSVSMHMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGLHGFNFFSVTPLGVVVLALGIVYMLVMRFMLKGDAPGQQAGKRRTFRDL
                     IREYRLTGRARRLAIRPGSPMVGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVNGV
                     SEFRARDVLLIDMSAAEVDLREFCAEQLLEPMVLRGEYFSDQALDVGMAEISLIPKSE
                     LIGKSVREIAFRTRYGLNVVGLKRDGVALEGSLADEPLLMGDIILVVGNWKLISLLGQ
                     KGRDFVVLNMPVEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPSAAIIACLLMGK
                     FRCIDAESAYKAIHWPSIILIVGMMPFALALQKTGGVSLVVQGLMDIGGGYGPYMMLG
                     CLFVLCAVIGLFISNTATAVLMAPIALAAAKSMGVSPYPFAMAVAMAASAAFMTPVSS
                     PVNTLVLGPGNYSFSDFVKLGVPFTLIVMAVCIVMIPMLFPF"
     gene            complement(4349..5026)
                     /locus_tag="OPY25_001200"
     CDS             complement(4349..5026)
                     /locus_tag="OPY25_001200"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461276.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphatase"
                     /protein_id="HCS0926854.1"
                     /translation="MPEEAHVQCKGFLFDLDGTLVDSLPAVERAWCSWADRFNLAHDE
                     VLGFIHGKQAITSLRHFMAGKSEAEIAAEFTRLEQIEATETAGITALPGAVDLLNHLN
                     KAGIPWAIVTSGSMPVARARHQVAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLA
                     PQECVVVEDAPAGVLSGLAAGCHVIAVNAPADTPRLADVDFALDSLTQLSVAKQPNGD
                     VVVLRKT"
     gene            complement(5019..5513)
                     /locus_tag="OPY25_001201"
     CDS             complement(5019..5513)
                     /locus_tag="OPY25_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HCS0926855.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPTNAERYRRLQTIIERGYGLQM
                     RELDREFGELTEETCRTIIDIMEMYHALHVSWTNLKDTQAIDERRVTFLGFDAATEAR
                     YLGYVRFMVNIEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(5596..6051)
                     /locus_tag="OPY25_001202"
     CDS             complement(5596..6051)
                     /locus_tag="OPY25_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HCS0926856.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYAKTWPMEKRLAPVFVENRVIRMT
                     RYAIRFMPPVAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSLTPLPPSI
                     LNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            6391..7593
                     /gene="ackA"
                     /locus_tag="OPY25_001203"
     CDS             6391..7593
                     /gene="ackA"
                     /locus_tag="OPY25_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCS0926857.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGDEYLSGLAECFHLPEARI
                     KWKMDGSKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDSASFAPLHNPAHLIGIAEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYSLYKEHGVRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDQINKMLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGSYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            7670..9814
                     /gene="pta"
                     /locus_tag="OPY25_001204"
     CDS             7670..9814
                     /gene="pta"
                     /locus_tag="OPY25_001204"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCS0926858.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     AGGDAPDQTTTIVRANSTLPAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTKDAE
                     VVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGG
                     AKNTNITGVIINKLNAPVDEQGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLG
                     AVPWSFDLIATRAIDMARHLNATIINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLL
                     VTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNTN
                     TWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYVNADWIESLTATSERSRRLSPPAFR
                     YQLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAASQGVE
                     LGAGIEIVDPEVVRESYVARLVELRKSKGMTEPVAREQLEDNVVLGTLMLEQDEVDGL
                     VSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQLA
                     EIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPL
                     QYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGM
                     RKPVNDLSRGALVDDIVYTIALTAIQASQQQQ"
     gene            10032..11552
                     /gene="yfcC"
                     /locus_tag="OPY25_001205"
     CDS             10032..11552
                     /gene="yfcC"
                     /locus_tag="OPY25_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCS0926859.1"
                     /translation="MSVVTESKTARKWAMPDTLVIIFFVAILTSIATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRIVTNEAGEAQYHRVQFFTTGDERPGLMNFPFEGLTS
                     GSKFGTAVGIIMFMLVIGGAFGIVMRTGTVDNGILALIRHTRGNEVLFIPVLFVLFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWIVATLIGLVFTLVYASRVKKNPLLSRVHESDRYFREQQDE
                     VVQRPFTFGDWLVLLVLTGVMIWVVWGVIVHAWFIPEIASQFFTMGVVIGLIGVIFRL
                     NGMTVNVMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGEPSVLNTLLNSIAHGI
                     SGLNNAIAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGASLLGLLFIMSSVVVIGAQMMGYH"
     gene            complement(11601..12554)
                     /locus_tag="OPY25_001206"
     CDS             complement(11601..12554)
                     /locus_tag="OPY25_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HCS0926860.1"
                     /translation="MIKLAPAGLKDDIEMRKVYAGFVAGQIEAGSPIIALEADLMSSM
                     AMDSVARDYPQHVINCGIMEANVIGTAAGLALTGRKPFVHTFTAFASRRCFDQLFMAL
                     DYQRNNVKVIASDAGVTACHNGGTHMSFEDMGIVRGLAHSVVLEVTDAVMFANILRQL
                     MDLDGFYWLRTIRKQATSIYAPGSTFTIGKGNVLREGDDITLIANGIMVAEALEAARQ
                     LEQEGVSAAVIDMFTLKPIDRMLVKNYAEKTRRIVTCENHSIHNGLGSAVAEVLVENC
                     PVPMRRVGVKERYGQVGTQDFLQQEYGLTAAAIVEAAKSLL"
     gene            complement(12547..13377)
                     /locus_tag="OPY25_001207"
     CDS             complement(12547..13377)
                     /locus_tag="OPY25_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCS0926861.1"
                     /translation="MNVTEITQLARDIRVATLKSLNHLGFGHYGGSMSVVETLAVLYG
                     AVMKIDPADPDWPERDYFVLSKGHAGPALYSTLAIKGYFPREELNTLNQNGTRLPSHP
                     DRLKTHGVDATTGSLGQGISIAGGMALSHKLARRPNRVFCIVGDGELNEGQCWEAFQF
                     IAHHRLNNLTVFIDWNKQQLDGELEEIINPFDLEGKFRAFGFDVVTVKGDDIAGLLAV
                     VQPVPPADARPRVVILDSIKGQGVPCLEQLTNSHHLRLTDGMKQTLNEAIHQLEVMHD
                     "
     gene            complement(13374..14765)
                     /locus_tag="OPY25_001208"
     CDS             complement(13374..14765)
                     /locus_tag="OPY25_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461284.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCS0926862.1"
                     /translation="MFILETLNFVVDILKVPSVLVGLIALIGLVAQKKAFSDVVKGTI
                     KTILGFIVLGGGATVLVGSLNPLGGMFEHAFNIQGIIPNNEAIVSIALEKYGASTALI
                     MAFGMVANIVVARFTRLKYIFLTGHHTFYMACMIGVILTVAGFEGVGLVFTGSLILGL
                     VMAFFPALAQRYMRRITGTDDIAFGHFGTLGYVLSGWIGSLCGKGSRSTEEMNLPKNL
                     SFLRDSSISISLTMMIIYLIMAVSAGREYVEATFSGGQNYLVYAIIMAITFAAGVFII
                     LQGVRLILAEIVPAFTGFSEKLVPNARPALDCPVVYPYAPNAVLIGFLFSFLGGLVGL
                     FLLGQMKLVLILPGVVPHFFTGATAGVFGNATGGRRGAMIGAFANGLLITFLPVLLLP
                     VLGAIGFANTTFSDADFGVIGILLGNLARYLSPMAITGLVVALFALLVAYNVLAKSKK
                     ATAEVQENSGAKE"
     gene            complement(14786..15058)
                     /locus_tag="OPY25_001209"
     CDS             complement(14786..15058)
                     /locus_tag="OPY25_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCS0926863.1"
                     /translation="MKIMAICGSGLGSSFMVEMNIKKVLKKLNIDAEVEHSDLSSATP
                     GAADLFVMAKDIAASASVPESQLVVINNIIDINELETQLRAWFAKQ"
     gene            complement(15139..15582)
                     /locus_tag="OPY25_001210"
     CDS             complement(15139..15582)
                     /locus_tag="OPY25_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCS0926864.1"
                     /translation="MLGTWLSDATITLRESVETWPQALEICGKPLLDAGVIAPEYITA
                     IVQQHQKLGPYYVLAPGLAMPHARPEEGAKGLGLSLLKLQRGVSFGADEFDPVDIIIM
                     LAAPDKHSHIEMISALAELFSSDVDMEKLHQAKNLEDIKTIIDRF"
     gene            15835..16854
                     /locus_tag="OPY25_001211"
     CDS             15835..16854
                     /locus_tag="OPY25_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCS0926865.1"
                     /translation="MSIPRKRRSTGKVTIADVAQLAGVGTMTVSRALRTPEQVSDKLR
                     EKIEAAVHELGYMPNLAASALASASSHTIAMVVPNLAEAGCSEMFAGLQQILQPAGYQ
                     IMLAESQHRVEQEEKLLETLLASNIAAAILLSVEHSTTVRQWLKNASIPVMEMGAIRS
                     DPIDMNIGIDNVAAMYELTEMLIQRGYQNIGLLCANQEQWIFQQHLHGWYKAMLRHHM
                     SPNRVINAALPPNFSTGASQLPEFLLAWPELDALVCVSDELACGALYECQRRRIKVPD
                     DLAVVGFGDSDVSRVCQPPLTTMAVPHRKIGSEAGRALLERLNQGNWSDRKSIASSLC
                     MRESC"
     gene            complement(16860..17414)
                     /gene="yfcD"
                     /locus_tag="OPY25_001212"
     CDS             complement(16860..17414)
                     /gene="yfcD"
                     /locus_tag="OPY25_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HCS0926866.1"
                     /translation="MVEQRRLASTEWVDIVNEDNEVIAQSSREQMRAQRLRHRATYIV
                     VHDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFA
                     EHGLFYFEDQHCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLK
                     ALALWMTRNAKNEAALQEKPEETE"
     gene            complement(17471..18022)
                     /gene="yfcE"
                     /locus_tag="OPY25_001213"
     CDS             complement(17471..18022)
                     /gene="yfcE"
                     /locus_tag="OPY25_001213"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HCS0926867.1"
                     /translation="MKLMFASDIHGSLPATERVLERFAQSGARWLVILGDVLNHGPRN
                     ALPEGYAPAQVAERLNAVATQIIAVRGNCDSEVDQMLLHFPITAPWQQILTQERRLFL
                     THGHLFGPTNLPALHTGDVLVYGHTHLPVAQQQEGLYHFNPGSVSIPKGGYAASYGIL
                     DDNVLSVIALNDQSIIAQVAINS"
     gene            complement(18078..18722)
                     /gene="yfcF"
                     /locus_tag="OPY25_001214"
                     /pseudo
     CDS             complement(18078..18722)
                     /gene="yfcF"
                     /locus_tag="OPY25_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
     gene            18865..19512
                     /gene="yfcG"
                     /locus_tag="OPY25_001215"
     CDS             18865..19512
                     /gene="yfcG"
                     /locus_tag="OPY25_001215"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HCS0926868.1"
                     /translation="MIDLYYAPTPNGHKIMLFLEEAELAYRLLKVDISKGNQFRPDFL
                     AISPNNKIPAIVDHAPADGGQPLSLFESGEILLYLAEKSGKLLSGELRERHTTLQWLF
                     WQVGGLGPMLGQNHHFNHFAPQAIPYAIERYQVETQRLYNVLNKRLETSPWLGGDHYS
                     IADIASWPWVNAHQRQRIDLDTYPAVYNWFERIRTRPATARALLQAQLHCNSTKA"
     gene            19636..20529
                     /locus_tag="OPY25_001216"
     CDS             19636..20529
                     /locus_tag="OPY25_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HCS0926869.1"
                     /translation="MQILITGGTGLIGRHLIPRLLILGHQVTVVTRNPDNARQILDSR
                     VTLWKGLAEREHLNEIDAIINLAGEPIADKRWTSQQKERLCQSRWAITQKLVDLIHAS
                     ATPPSVLISGSATGYYGDLGDVVVTEDEPPHNEFTHKLCARWEQIACRAQSDQTRVCL
                     LRTGVVLAPQGGILGKMVPPFRLGLGGPVGNGRQYLAWIHIDDMVNGILWLLDNDLRG
                     PFNMVSPYPVHNEQFAHALGRALRRPAIIRIPATAIRLLMGESSVLVLGGQRALPKRL
                     EAAGFAFRWYDLEEALADVIR"
     gene            complement(20581..21354)
                     /gene="hisP"
                     /locus_tag="OPY25_001217"
     CDS             complement(20581..21354)
                     /gene="hisP"
                     /locus_tag="OPY25_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HCS0926870.1"
                     /translation="MSENKLHVIDLHKRYGGHEVLKGVSLQARAGDVISIIGSSGSGK
                     STFLRCINFLEKSSEGAIIVNGQNINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWNHMTVLENVMEAPIQVLGLSKHDARERALKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPDVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     SSHVIFLHQGKIEEEGNPEQVFGNPQSPRLQQFLKGSLK"
     gene            complement(21368..22075)
                     /gene="hisM"
                     /locus_tag="OPY25_001218"
     CDS             complement(21368..22075)
                     /gene="hisM"
                     /locus_tag="OPY25_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisM"
                     /protein_id="HCS0926871.1"
                     /translation="MIEIIQEYWKSLLWTDGYRFTGVAITLWLLISSVVMGGLLAVIL
                     AVGRVSSNKFIRFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTDLLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSSFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLLISYVLI
                     SLFRRAERRWLQHVSSK"
     gene            complement(22072..22758)
                     /locus_tag="OPY25_001219"
     CDS             complement(22072..22758)
                     /locus_tag="OPY25_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HCS0926872.1"
                     /translation="MLYGFSGVILQGAIVTLELALSSVVLAVLIGLVGAGAKLSQNRV
                     TGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNVVTDSLGIDQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTHGQTFRRIMFPAMMRYALPGIGNNWQV
                     ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGLIYLVFTTVSNGVLLLLERR
                     YSVGVKRADL"
     gene            complement(22941..23723)
                     /gene="hisJ"
                     /locus_tag="OPY25_001220"
     CDS             complement(22941..23723)
                     /gene="hisJ"
                     /locus_tag="OPY25_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HCS0926873.1"
                     /translation="MKKLALSLSLVLAFSSATAAFAAIPQKIRIGTDPTYAPFESKNA
                     QGELVGFDIDLAKELCNRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVASLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPIGKDYKFGGPAVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(23961..24743)
                     /gene="argT"
                     /locus_tag="OPY25_001221"
     CDS             complement(23961..24743)
                     /gene="argT"
                     /locus_tag="OPY25_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HCS0926874.1"
                     /translation="MKKTVLALSLLIGLGATAASYAALPQTVRIGTDTTYAPFSSKDA
                     KGDFIGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLESLKGKHVGVLQGSTQEAYANDNWRTKGVDVV
                     AYANQDLIYSDLTAGRLDAALQDEVAASEGFLKQPAGKEYAFAGPSVKDKKYFGDGTG
                     VGLRKDDTELKAAFDKALTELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(25032..25601)
                     /locus_tag="OPY25_001222"
     CDS             complement(25032..25601)
                     /locus_tag="OPY25_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCS0926875.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQILRDVDSVETHLVMSQAARQTL
                     ALETHFSLREVQALADVTHDARDIAASISSGSYPTAGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVILKERRPLVLCVRETPLHIGHLRLMTQAAEIGAVIMPPVPAFYHLPQTLD
                     DVINQTVNRVLDQFDIPLPHDLFVRWQGA"
     gene            complement(25628..27034)
                     /locus_tag="OPY25_001223"
                     /pseudo
     CDS             complement(25628..27034)
                     /locus_tag="OPY25_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461299.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(27098..28201)
                     /locus_tag="OPY25_001224"
     CDS             complement(27098..28201)
                     /locus_tag="OPY25_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HCS0926876.1"
                     /translation="MYMPVLEINLRKLEENARTEKALLASSGIDVMAVNKVFDGCVET
                     AQAVLNGGITVIAESRTYNLKKIRETGCTTCLLRSPCLSEIEDVVRYADISLNSEPVV
                     LRALSQEAQRQGKTHQVLLMVDMGDLREGIWFGEYQRILETVTLITGLPGLELYGLGT
                     NFNCYGTVLPTVKNGEDFLALAARLEADSGIPVRRLSAGNCTSYHLLDKGIWPQGLNH
                     LRIGGLHEFGIEYVDMKYLNEFHHSAKPVDKACSDMYILEAEIIELNSKPTVPVGELG
                     VDAFLQSKTFVDRGIRRRALLAFGRQDVPSDNCVPCDDAITILGQTSDHTLVDIEDCR
                     QSLKVGDVVRFELDYTGLLMACQTKGVAWRFTR"
     gene            complement(28203..29624)
                     /locus_tag="OPY25_001225"
     CDS             complement(28203..29624)
                     /locus_tag="OPY25_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCS0926877.1"
                     /translation="MSNTNSGLLGIKDIVFMNVIAILSLRQIPNVAPYGASAMLLWVI
                     AAFCLFFPLAMVCGELSTGWPKDGGIFVWIKEAFGKRIAWIVVVCFLFSCVLFFPLML
                     QFGFTALGYMIGGGLAENKAFIGIGSAVIFWLLTLMNIRGMEWTKIINSISAWCGVFI
                     PSAILILLAVVWLCTGHQMQTDYTTAKNWIPDLGHWDTIVFLSSMMFAFAGLEVAPMI
                     AGRTRNPQRDFPRAMAVSAAVIVGIYMVGTWALNTLLPAGKTDIVAGVMQAMHAAADT
                     LHMPWLIPVMAICMFFGALGQINSWLVGPIYMLQEASREDNLLGDRIGKLHPVWKTPA
                     FALTIQAIIVTVLCFSTFISPSVAAAYWMLTALTTITYFIPYLVMFPAFWRLRKTQPD
                     TPRSFKIPGKVLPAILPALGFLSIAFAVALLFIPPSQIDMGGYFQYAGKIIGGAVLAV
                     VVAEYIYHRAQKRNARLSMAGGK"
     gene            complement(29715..31112)
                     /locus_tag="OPY25_001226"
     CDS             complement(29715..31112)
                     /locus_tag="OPY25_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCS0926878.1"
                     /translation="MTDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQY
                     PTPFYVFSEPEIIRNIHEIQQAFAAHKNTKTFFASKTCSVMGVLKAIRDAGICAEANS
                     QYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKL
                     KKVANVCVRVEPNVPSATHAELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMH
                     VGDQVPESEPFAKATKVLVDESRRLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKD
                     NMYAGITAQDFADAVIREVHKWRTDVEICIEPGRKVTGSAAVLLTEVSCEKRKTNYDL
                     NGNVECHVEWKFVDAGYSVLSDSQHFDWFFYVYNASRMTAAHDAWIKLAGPLCDGGDY
                     FHMGVKGEEFLLPKETHVGDIVAFLDAGAYTIESQTVYNNRPRTGVVMIDKNGETRLI
                     RREDSYEDMVKYDIY"
     gene            31323..32750
                     /locus_tag="OPY25_001227"
     CDS             31323..32750
                     /locus_tag="OPY25_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HCS0926879.1"
                     /translation="MASTNQELASALRMFSRFFDLIHQPLAVINERGEYVYYNQESAD
                     LDGYSIERAMGKHMLDVYPGMKETQSTMLSSLKKGVEYIGHYQIYYNARGQAVDYQHT
                     TASLYASDGGMVGVIEIGRNMSGVRRLQEQVVELNQLLYADHHEKHHAIITENPEMLS
                     NIAKAKRLAASNIPVTIVGETGTGKELFSRLIHQCSKRANKPFIALNCGALPPTLIES
                     TLFGTVRGAYTGAENSQGYLELANGGTLFLDELNAMPIEMQSKLLRFLQDKTFWRLGG
                     QQQLHSDVRIVAAMNEAPVKLIQQERLRADLFYRLSVGMLTLPPLRARPEDIPLLANY
                     FIDKYRNDVPQDIHGLSETARADLLNHAWPGNVRMLENAIVRSMIMQEKDGLLKHIIF
                     EQDELNLGVPETAPENPLPSSPDPQYEGSLEVRVANYERHLIETALDTHQGNIAAAAR
                     SLNVSRTTLQYKVQKYAIRFGVVRN"
     gene            complement(32786..34303)
                     /gene="purF"
                     /locus_tag="OPY25_001228"
     CDS             complement(32786..34303)
                     /gene="purF"
                     /locus_tag="OPY25_001228"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCS0926880.1"
                     /translation="MCGIVGISGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVNDIFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDSFRHYPLEADNIFAAIAAT
                     NRQIRGAYACVAMIIGHGMVAFRDPHGIRPLVLGKRDVGDGRTEYMVASESVALDTLG
                     FEFLRDVAPGEAIYITEKGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPTANELIAHGREVDEIRQIIGADGLIFQDLNDLIEAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQQYLDFLDSLRNDDAKAVLFQNEMENLEMHNEG"
     gene            complement(34341..34829)
                     /gene="cvpA"
                     /locus_tag="OPY25_001229"
     CDS             complement(34341..34829)
                     /gene="cvpA"
                     /locus_tag="OPY25_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HCS0926881.1"
                     /translation="MVWIDYAIIAVIAFSCLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGI
                     CFGALRGALIVAAILFFLDTFTGLSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RT"
     gene            complement(35140..35814)
                     /gene="dedD"
                     /locus_tag="OPY25_001230"
     CDS             complement(35140..35814)
                     /gene="dedD"
                     /locus_tag="OPY25_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HCS0926882.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKPGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPSRMASNNVELDPIPV
                     ETPKPKPVEKPKPQPKPQQPVVAVSTPTPAPQPATDDKPAPTGKAYVVQLGALKNADK
                     VNEIVGKLRSAGFRVYTSPSTPVQGKITRILVGPDASKDKMKGSLGELKQISGLSGVV
                     MGYSPN"
     gene            complement(35804..37072)
                     /gene="folC"
                     /locus_tag="OPY25_001231"
     CDS             complement(35804..37072)
                     /gene="folC"
                     /locus_tag="OPY25_001231"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCS0926883.1"
                     /translation="MKNKSIPQAASPLASWLSYLENLHSKSIDLGLERVSQVAARLDI
                     LKPAPFVFTVAGTNGKGTTCRTLESVLIAAGYRVGVYSSPHLVRYTERVRVQGKELAE
                     SAHTASFAEIEAARGDISLTYFEYGTLSALWLFKQANLDVVILEVGLGGRLDATNIVD
                     ADVAVITSIALDHTDWLGPDRESIGREKAGIFRAEKPAIVGEPEMPATIADVAQETGA
                     LLLRRGVDWRYEVTATHWAFTDGDGTLAGLPLPQVPQPNAATALAALRASGLNIDEQA
                     IRDGIAQATLPGRFQIVSESPRVIFDVAHNPHAAEYLTGRLKMLPKRGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGKGNVYDSVAQAWQAAIDAA
                     QPEDTVLVCGSFHTVAHVMEVIDAGRIGGE"
     gene            complement(37140..38054)
                     /gene="accD"
                     /locus_tag="OPY25_001232"
     CDS             complement(37140..38054)
                     /gene="accD"
                     /locus_tag="OPY25_001232"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HCS0926884.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPDAPREGVVVPPAPDQESEA"
     gene            complement(38204..38863)
                     /locus_tag="OPY25_001233"
     CDS             complement(38204..38863)
                     /locus_tag="OPY25_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCS0926885.1"
                     /translation="MDLIYFIIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHVMVALMLIAAIVGDAVNYTIGRLFGEKLFS
                     NPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLLFTYAGYFFGTIPLIQDNLKLLIVGIIVVSILPGVIEIVRHKRAASRAA
                     K"
     gene            complement(38912..39724)
                     /gene="truA"
                     /locus_tag="OPY25_001234"
     CDS             complement(38912..39724)
                     /gene="truA"
                     /locus_tag="OPY25_001234"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCS0926886.1"
                     /translation="MSGQQSSPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPINVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKT
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLAKGVTHYYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLLEVGAHN
                     QPESWIAELLAARDRTLAAATAKAEGLYLVAVDYPDRFDLPKPPMGPLFLAD"
     gene            complement(39724..40737)
                     /locus_tag="OPY25_001235"
     CDS             complement(39724..40737)
                     /locus_tag="OPY25_001235"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCS0926887.1"
                     /translation="MSEGWNIAILGATGAVGEALLETLAERQFPVGEIYALARHESAG
                     EHLRFGGKSVIVQDAADFDWTQAQLAFFVAGAEASAAWIDDATNAGCLVIDSSGLFAL
                     EPDVPLVVPEVNPYVLADYRNRNVIAVADSLTSQLLAALKPLIDQGGLSRIAVTSMLS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEDDFFGRQLAFNMLPLLPDREGSVRQERRIVD
                     EVRKILQDDGVMISASVVQSPVFYGHAQMVSFEALRPLAAEEAREAFSRGEDIVLSEE
                     TDYPTQVGDASGNPQLSIGCVHNDYGMPEQIQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(40805..41941)
                     /gene="pdxB"
                     /locus_tag="OPY25_001236"
     CDS             complement(40805..41941)
                     /gene="pdxB"
                     /locus_tag="OPY25_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HCS0926888.1"
                     /translation="MKILVDENMPYARELFSRLGEVKAVPGRPIPVEELNHADALMVR
                     SVTKVNESLLSGTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSA
                     LLMLAERDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDPPRAARGDEGDFRT
                     LDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALL
                     ARLNAGQPLSVVLDVWEGEPDLNVALLEAVDIGTSHIAGYTLEGKARGTTQVFEAYSA
                     FIGREQRVALETLLPAPEFGRITLHGPLDQPTLKRLAHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVMCDDETAAALLCKLGFNAVHHPAH"
     gene            42045..43046
                     /gene="flk"
                     /locus_tag="OPY25_001237"
     CDS             42045..43046
                     /gene="flk"
                     /locus_tag="OPY25_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HCS0926889.1"
                     /translation="MHPISGAPAQPPGEGRNPLSAASEQPLSMQQRTVLERLITRLIS
                     LTQQQSAEVWAGMKHDLGIKNDAPLLSRHFPAAEQNLTQRLGVAQQNHANRQVLSQLT
                     ELLGVGNNRQAVSDFIRQQYGQTALSQLTPDQLKNVLTLLQQGQLSIPQPQQRPATDR
                     PLLPAEHNTLNQLVTKLAAATGESNKLIWQSMLELSGVKSGELIPAKQFTHLATWLQA
                     RQTLSLQHAPTLHTLQAALKQPLEPDELTAIKEYAQHTYQIQPQTVLTTAQVQDLLNH
                     IFLRRVEREADELEPLSIQPIYRPFAPMIETVKNLSARPGLLFIALIIVLALFWLVS"
     gene            complement(43043..44221)
                     /locus_tag="OPY25_001238"
     CDS             complement(43043..44221)
                     /locus_tag="OPY25_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0926890.1"
                     /translation="MTAVSQKTTTPSADFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYSNTMVGIAVGIQFFATVLTRGYAGRLADQYGAKRSALQGMLACGLAGAAWLLAA
                     LLPVSAPVKFALLIVGRLILGFGESQLLTGTLTWGLGLVGPTRSGKVMSWNGMAIYGA
                     LAAGAPLGLLIHSHFGFAALAGTTMVLPLLAWAFNGTVRKVPAYTGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFISLYFVSNGWTMAGFTLTAFGGAFVLMRILFGWMPDRF
                     GGVKVAVVSLLVETAGLLLLWLAPTAWIALVGAALTGAGCSLIFSALGVEVVKRVPAQ
                     VRGTALGGYAAFQDISYGVTGPLAGMLATSYGYPSVFLAGAISAVVGILVTILSFRRG
                     "
     gene            complement(44401..44775)
                     /locus_tag="OPY25_001239"
     CDS             complement(44401..44775)
                     /locus_tag="OPY25_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926891.1"
                     /translation="MAKEWFTVKECLGLPGFPGSEPAVRERLYKYSEGKAGVRRKRVK
                     SKAEEFHISVFPLYVHRYLDDSGEEPTPEPISLQEAEPEDIWEMMFRLLTPEQRKQVT
                     GRFKVRGMKAVFLFLFDDTPPR"
     gene            44947..>45174
                     /locus_tag="OPY25_001240"
     CDS             44947..>45174
                     /locus_tag="OPY25_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0926892.1"
                     /translation="MEPKSQDWHRADIKSALEKRGITLRDLSRQAGLSPDSLRNVFTR
                     SWPRAERIIADALGITPQEIWPSRYGDMQIKN"
BASE COUNT        11092 a        12818 c        11248 g        10016 t
ORIGIN      
        1 ttacgacttt agtaaatgct ttttaaatat taaataataa ttaattaaga tttctaccat
       61 tcattaatta tacttaacaa tagtttcaca ccacccgccg ccggaaaggt ctaaccttct
      121 cattttacct ttaatactca gtatttccga aatagccgac gcgacactaa tgatgaatgc
      181 ttatctctca taaaacagat aatttctgac aacataaaaa accacattac gcgcaaccac
      241 atagaacaaa acactataca tacagacaaa aatagaaaat gcatctaacc aaatgatttt
      301 atgaagtttt aaacagtacg aaagcgcgtt aaaaataaac aaaatcttct tctgttcact
      361 cttcaaaact caccgtcgtg ggagtacatt gtttcgtgct gacttccacg gcagggagtg
      421 gcaataacag ctaaaaggtc aagattcatg tcccccattg aaaaatccag caaactcgaa
      481 aatgtctgtt atgacattcg tggccccgtt ctgaaagaag cgaaacgcct tgaggaagaa
      541 ggtaataaag ttcttaaact gaatatcggc aaccccgccc ccttcggatt cgaagcgccg
      601 gacgaaattc tggtcgatgt cattcgtaat ttgccgacgg cgcaaggata ttgcgactcg
      661 aaagggcttt attccgcccg taaagcgatt atgcagcatt atcaggcccg tggaatgcgc
      721 gatgtaaccg tggaagatat ctatatcggt aacggcgttt ccgagctgat cgttcaggcg
      781 atgcaggcgt tgcttaacag tggcgatgaa atgctggttc ccgcgcccga ttatccgtta
      841 tggacagcag cggtatcgct ctccagcggc aaggcggtac attatctttg cgatgaatct
      901 tccgactggt tcccggacct tgacgatatc cgcgccaaaa tcaccccacg tacgcgtggt
      961 attgtcatta ttaatccaaa caaccctact ggcgccgtct attctaaaga attgttgatg
     1021 gaaattgtca acattgcgcg cgagcataat ctcatcatct tcgccgatga aatttatgac
     1081 aagattctct atgacgatgc cgaacatcac tctatcgccg cactggcgcc tgatctgctg
     1141 accatcacct ttaatggttt gtctaaaacc tatcgcgtcg ccggcttccg ccagggctgg
     1201 atggtgctga acgggccgaa aaaacatgcg aaaggctata ttgaagggct ggagatgtta
     1261 gcctcaatgc gcctgtgcgc caacgtcccg gcgcaacatg ctattcagac cgcgctcggc
     1321 ggctatcaaa gcattagcga atttattctg ccgggcggtc gactgtatga acagcgtaac
     1381 cgcgcctggg agttgattaa cgatattccc ggcgtttcct gcgtaaaacc gcgcggcgcg
     1441 ttgtacatgt tccccaggat cgacgctaaa cgttttaata ttcacgacga ccagaagatg
     1501 gtgctggact tcctgctaca ggaaaaggtg ctgctggtgc aaggtaccgc ctttaactgg
     1561 ccgtggccgg atcacttccg cattgtgacg ctaccgcgtg aagatgacct ggagatggcc
     1621 atcaaccgct ttgggcgttt cctctcaggc taccatcaat aatcttaaat tcaggctact
     1681 tcggtagcct gaattgcatc ttcatcaccc tccccgcaca atgaagtctg ccgcagtgaa
     1741 aacaaaaggt aatctatgaa gcagagccat tttttcgccc atctctcccg catgaagttg
     1801 attaaccgct ggccgctgat gcgtaacgtg cgtacggaaa acgtctccga acatagtctg
     1861 caggtggcga tggtcgccca tgcgttggcg gcgataaaaa accgtaaatt tggcggccag
     1921 ctcaatgctg aacgcatcgc gcttctggcg atgtatcatg atgcctcgga agtactgacc
     1981 ggcgatctgc caacgccggt aaaatatttt aattcccaga tagctcagga atataaagcg
     2041 atcgaaaaaa tcgcccagca aaagctggtt gatatggcgc cggatgaatt acacgatatt
     2101 ttcgcaccgc ttattgatga gaatgcctgg agcaaagaag aacaggcaat cgtaaagcag
     2161 gccgatgcgc tttgcgccta cctgaaatgc ctggaggagc tctcagcggg aaataatgag
     2221 tttagactgg caaaaacgcg gctggaaaaa acgctggaat tacgtcgcag ccaggagatg
     2281 gactatttta tggcggtgtt cgtgccaagt ttccatctct ctcttgacga gataagccag
     2341 gattcaccgc tttagttgcc ggatggcggc taacgcctta tccggcctac cgttcttccc
     2401 gtaggcctga taagcgtagc gccatcaggc cttttccagc ctggggttaa aacggaaaca
     2461 acatcggaat catcacaata caaaccgcca tcacaataag cgtgaacggc acgccaagct
     2521 tcacaaaatc gctaaagcta tagtttcccg gccccagaac cagagtattg accggcgatg
     2581 aaaccggcgt cataaaggcg gcggatgccg ccatcgctac tgccatcgca aacggatagg
     2641 gcgacacccc catcgatttc gccgccgcca gcgcaatcgg cgccatcagc accgccgttg
     2701 ccgtgttaga aatgaacagt cctatgacgg cgcacagcac gaacaggcat cccagcatca
     2761 tatacggccc atagccgccg ccgatatcca ttaacccttg cacgaccaga gagacgccgc
     2821 cggttttttg caacgccagc gcaaacggca tcatacccac aatcaagata atactcggcc
     2881 agtggatcgc tttatacgcg ctttcagcat caatacagcg aaatttcccc atcagcaggc
     2941 aggcgataat cgccgcgctc ggattgggaa tttcatcggt caacatcagc gccaccatca
     3001 gtaccaggca gaaaatggcg tgcggcgcct ggctgtgcgc cggcgaggct tcgctgacct
     3061 cgaccggcat attcagcacc acaaagtcgc ggcctttttg ccccagcagg ctgattaact
     3121 tccagttccc cacgaccaga atgatatcgc ccatcaataa cggttcatcg gccagcgacc
     3181 cttccagcgc gacgccgtcg cgtttcaggc cgaccacatt cagcccgtaa cgtgtacgga
     3241 aggcgatttc acgcaccgac ttgcctatca gttcagactt cggaataagc gaaatttccg
     3301 ccatgccaac atccaacgcc tgatcggaaa aatattctcc acgcaatacc atcggttcca
     3361 gcagttgctc ggcgcagaac tctctgaggt caacctccgc cgccgacata tcaatcagca
     3421 gaacgtcgcg agcgcgaaac tccgatacgc cgttcacatt gacgataacc cgccgaaagc
     3481 gccgccagcg ttcaacgccg atgacattgg cgccgtaacg ttcgcgcagt ttaaggtcgt
     3541 ccagccgctg tcccaccatc ggcgaaccgg ggcgaatcgc cagacgacgc gcgcgccccg
     3601 tcagacggta ctcgcggata agatcgcgga aagtgcgacg cttaccggcc tgttgtccgg
     3661 gcgcatcgcc ttttagcatg aagcgcatca ccagcatata aacaatgccg agcgccaaca
     3721 ccactacccc cagcggcgtc acgctaaaaa agttgaaccc gtgcaggcct tcacgcagca
     3781 gttcactgtt aaccaccagg ttcggcggcg tcgccaccag cgtcatcatt ccgctgataa
     3841 gcccggcaaa actcagcggc atcatcaggc gcgaaggcga ggtctgcata tgcatagaaa
     3901 cgctaagaac aacggggata aaaatcgcca ccacgccggt tgaactcatg aaagcaccaa
     3961 gtccggcgac ggtgatcatc agtaaaacca gcatcttgat ttcactgctg cccgccattt
     4021 taaccagcca ggtaccgacc accgtcgcaa cgccggtgcg cacgaggccg tcgccaataa
     4081 taaataaggc ggcgataaga atgacattcg gatcgctaaa gccggagaag gcttccgaaa
     4141 gggtcaaggt accgctaagg acaaaagcaa caatgacgaa taaagccacc gcatccatac
     4201 gtactttgcc cgtcgcaaac aacacgacgg caatcgccag taaagagaga acccaaatca
     4261 attcaccgtt cacaacatat ccttgtcaga tgagaagata acgtgattct gccataaata
     4321 tgccccgcca gggcggggca tatcatgatc aggtctttct taacaccacc acatcgccgt
     4381 ttggttgttt agcgaccgat aattgcgtca ggctatccaa cgcaaaatca acatccgcca
     4441 gacgcggcgt gtcggccggc gcattgaccg caatgacgtg gcagcccgca gccagtccgg
     4501 acagcacgcc agccggggca tcttctacta cgacgcactc ctgaggggcc aggccaagca
     4561 gttgtgcgcc cagcaaatac gcatccggct ccggtttgcc gcgtttgact cgttcggcgg
     4621 tgacaaacac ctctggcgct ggaaggcccg cgacctgatg gcgcgcacgc gcgaccggca
     4681 ttgaaccgga ggtgacgata gcccacggaa tgcccgcttt attcaggtga ttgagtaaat
     4741 cgactgcccc cggcaacgcg gtgatccctg cggtttcagt ggcttctatt tgctccaggc
     4801 gcgtaaactc agcggcaatt tccgcctccg atttacccgc cataaaatgc cgcaacgagg
     4861 tgatcgcctg tttgccatga ataaagccca gcacctcatc atgagcaagg ttaaaacgat
     4921 cggcccagct acaccacgcg cgttcgacgg caggtaatga gtcaaccaac gttccatcca
     4981 gatcaaacag aaaaccttta cactgcacgt gagcctcctc aggcattaat gatttgattg
     5041 atttcattcg cgctcaggtg gtactgacgc gggcaggcat gccagacatt caacatccgc
     5101 tggtattttt cccacatcgg cgtctgggca ttaaagccgt gcgtcccggc gtcaaagtga
     5161 gtgtagcgtc cttctatatt caccataaaa cggacatagc cgaggtaacg cgcttccgtc
     5221 gcggcgtcaa accccaggaa ggtgacgcga cgttcgtcga tggcttgcgt atctttgagg
     5281 ttggtccagg agacgtgcag cgcatggtac atctccataa tatcgatgat ggtacgacag
     5341 gtctcttccg tcagctcgcc aaactcgcga tccagctcgc gcatctgcag gccgtagccg
     5401 cgttcaataa ttgtttgtaa gcgacggtaa cgctcggcgt tggtgggatc gagcatcgtc
     5461 atcattttgt actggttaga caaaatcaga cgttgcgcgt tggtcatttc cattttgaac
     5521 tcctgtatca cgctatggcg atgaaaaaaa gaaggcattg gtatgccttc ttttatatgc
     5581 gtaatccggg gtcaattaca aatcatccaa gaaagtttta tccagttgtt tgaaggcgcg
     5641 cttaagcgtg tcagctaatg cctggtaatc cggctttcct tctaccggcg ccagcgcttg
     5701 tccagcctcc tgcaatttac cgcgaacttc gtaaaaccag ttaaggattg aaggcggcaa
     5761 tggcgtcaag gaacgtttcc ctaaccacca taatccctgc ataggcaagc tcagggcgaa
     5821 cagggcggtc gccacggccg gacctaactg accgcccagc gctatctgcc agcataatgt
     5881 aaagacggcg acaggcggca taaatcgtat ggcatagcgc gtcatacgaa tgacgcggtt
     5941 ttcgacgaaa acgggcgcca gccgcttttc catcggccac gtcttcgcgt agtgctgccc
     6001 ccggcgaaat aagctaaaaa aatttacgga gcgattatcc ggcgtcgaca tggcctacct
     6061 caatttcaca tataaaattt aaaaaatttg tgcaaaacaa caactgcgag ggacaacgtt
     6121 caaaacattt tgtcttcgat acccactatc aggtatcctg tgtcggcctg tcaaaggccg
     6181 gtagtttaaa atcattgagt cgtcaatatt acacatagta tgccattggc tgaaaaatac
     6241 gcaaaatggc atagactcaa aggtatttct tccatcatgc ccaaaaaaac tcctgcgcat
     6301 gatgttaatc ataaatgtca gggctatcat gcgctacgct ctatggctca ctgacgtttt
     6361 tttagccacg tatcataaat aggtacttcc atgtcgagta agttagtact ggttctgaac
     6421 tgcggtagtt cttcactgaa atttgcaatt attgatgcag ttaatggtga tgaatacctt
     6481 tctggtttag ccgaatgttt ccatctgcca gaagcacgca tcaaatggaa aatggacggc
     6541 agtaaacaag aagcggcttt aggtgcaggc gccgctcaca gtgaagcgct gaactttatc
     6601 gttaacacta ttctggcaca aaaaccagaa ctgtctgcgc agttaactgc aattggtcac
     6661 cgtatcgtac acggcggcga gaagtatacc agctccgtag tcattgatga gtccgtcatt
     6721 cagggcatca aagattccgc ctctttcgca ccgctgcata acccggctca cctgattggt
     6781 atcgccgaag cgctgaaatc tttcccgcag ctgaaagata aaaacgtcgc cgtgttcgac
     6841 accgccttcc atcagaccat gccggaagaa tcttacctgt atgccctgcc gtacagcctg
     6901 tataaagaac atggcgttcg tcgctatggc gcacacggca ccagccactt ctatgtaact
     6961 caggaagcgg caaaaatgct gaacaagccg gtagaagaac tgaacattat cacctgccac
     7021 ctgggcaacg gcggttctgt ttccgctatc cgtaacggta aatgcgtgga tacctctatg
     7081 ggtctgaccc cgctggaagg cctggtcatg ggtacccgtt ccggcgatat cgaccctgcg
     7141 attatcttcc acctgcacga cactctgggc atgagcgtgg atcagatcaa caaaatgctg
     7201 accaaagagt ccggtctgct gggtctgact gaagtgacca gcgactgccg ttatgttgaa
     7261 gacaactacg ccaccaaaga agacgcaaaa cgtgcgatgg acgtttactg ccaccgcctg
     7321 gcgaaataca tcggttctta caccgctctg atggacggtc gtctggatgc agtcgtgttc
     7381 accggcggta tcggtgaaaa cgccgcgatg gttcgcgagc tgtctctggg caaactgggc
     7441 gtactgggct ttgaagtcga ccacgaacgt aacctggcgg cccgcttcgg caaatctggt
     7501 ttcatcaaca aagaaggtac ccgtccggcg gtggtgatcc caaccaacga agaactggtt
     7561 atcgcgcagg acgcgagccg tctgactgcc tgatttcaca ccgccagcct cgctggcggt
     7621 gctgttttgt aacccgtccc caaaagacgg taacgaaaga ggataaaccg tgtcccgtat
     7681 tattatgctg atccctaccg gaaccagcgt cggtctgacc agcgtcagcc tcggcgtcat
     7741 ccgtgctatg gaacgcaaag gcgttcgtct gagcgtcttt aagcctatcg cccagcctcg
     7801 cgctggcggc gatgcgcctg accagaccac cactatcgtt cgcgcgaact ctaccctgcc
     7861 ggcggctgaa ccgctgaaga tgagccacgt tgaatctctg ctctccagca accagaaaga
     7921 cgtgctgatg gaagagatca tcgcaaacta ccatgcgaat accaaagacg cggaagtggt
     7981 gctggttgaa ggtctggttc cgacccgtaa acatcagttc gctcagtctc tgaactatga
     8041 aatcgcgaaa acgctgaatg cggaaatcgt ttttgtcatg tctcagggta ccgacacgcc
     8101 agaacagctg aacgagcgta tcgaactgac gcgcagcagc ttcggcggcg cgaaaaacac
     8161 caacatcacc ggcgttatca tcaacaaact gaatgcgccg gttgatgaac aaggccgtac
     8221 tcgcccggat ctgtcagaga tttttgacga ctcttccaaa gcgcaggtga tcaaaatcga
     8281 tcctgctaaa ctgcaggaat ccagcccgct gccggttctg ggcgcggtgc cgtggagctt
     8341 cgacctgatt gcgacccgcg ctatcgatat ggcgcgtcac ctgaacgcca ccatcattaa
     8401 cgaaggcgat atcaaaaccc gccgcgttaa atccgttacg ttctgcgcgc gcagtattcc
     8461 gcatatgctg gagcatttcc gcgcaggatc gttgttagtg acctcagctg accgtccgga
     8521 cgtactggtc gcagcttgcc tggccgcgat gaacggcgta gaaatcggcg ccctgctgct
     8581 gaccggcggc tatgaaatgg acgcgcgcat ttctaaactg tgcgaacgcg cattcgccac
     8641 cggtctgccg gtctttatgg tgaacaccaa cacctggcag acttcgctga gcctgcaaag
     8701 cttcaatctg gaagttccgg ttgatgacca tgagcgcatc gagaaagttc aggaatacgt
     8761 cgcgaactac gttaacgctg actggatcga gtcgctgacc gccacttccg agcgtagccg
     8821 tcgtctctct ccgccggcgt tccgctacca actgactgag ctggcgcgta aagccggtaa
     8881 acgcgtagtg ctgccggaag gcgacgaacc gcgtaccgtc aaagcggcgg caatctgcgc
     8941 tgaacgcggc atcgccactt gcgtactgct gggcaacccg gatgaaatca accgcgtcgc
     9001 ggcatctcag ggcgtagagc tgggcgcagg tattgaaatc gtcgatccgg aagtggtgcg
     9061 tgaaagctat gtcgctcgcc tggttgagct gcgtaagagc aaaggcatga ccgaaccggt
     9121 tgcccgcgaa cagctggaag acaacgtggt gctcggcacg ctgatgctgg agcaagacga
     9181 agtcgacggc ctggtttccg gcgcggttca taccaccgcc aacaccatcc gtccgccgct
     9241 gcagcttatt aaaacggcgc cgggtagctc cctggtctct tctgtgttct ttatgctact
     9301 gccggaacag gtttacgttt acggcgactg cgcaatcaac ccagacccga ctgcagagca
     9361 gctggcagaa atcgcgattc agtctgcgga ttccgccatt gccttcggca tcgaaccgcg
     9421 tgtggcaatg ctctcctact ccaccggcac ctctggcgcg ggcagcgacg tagagaaagt
     9481 acgtgaagcg acgcgtctgg cgcaggaaaa acgtcctgac ctgatgatcg acggtccgtt
     9541 gcagtacgac gccgcggtca tggctgacgt agcgaaatcc aaagcgccga actcgccggt
     9601 tgcgggtcgc gctaccgtgt tcattttccc ggatctgaac accggtaaca ccacctacaa
     9661 agcggtacag cgttctgccg acctgatctc catcgggccg atgctgcagg gtatgcgcaa
     9721 gccggtgaac gacctgtccc gtggcgcgct ggttgacgat atcgtctaca ccatcgccct
     9781 gacggcgatc caggcttctc aacagcagca gtaacagtaa aagctaatgc cggatggcgg
     9841 cgtgaacgcc ttgtccggcc tacaggtgag ataccgttgt aggccggata agacgcgtta
     9901 gcatcgccat ccggcattct gctatttacc ctgcaaagcg gaattttttg cttaactgcg
     9961 ctgcatcaat gaataactat tcccttcttc tcatacttgg cctctttgct ttgcaacagg
    10021 gatagtccgt catgtctgtc gttacagaat caaaaacagc cagaaaatgg gcaatgcccg
    10081 atacgctggt catcatcttt tttgtcgcca ttttaaccag tatcgccacc tgggtcgtcc
    10141 ccgttgggat gtttgatagc caggaagtgc agtatcaggt cgatggtcag acaaaaaccc
    10201 gcaaagtcgt cgacccgcac tcttttcgca ttgtgaccaa tgaggccggg gaagcgcagt
    10261 atcatcgcgt acaatttttc actaccggcg atgaaagacc agggctgatg aattttccgt
    10321 ttgaagggtt aacatccgga tcgaaattcg gcactgccgt cggcatcatt atgtttatgt
    10381 tggtgattgg cggcgcattc ggcatcgtga tgcgtaccgg caccgtggat aacggcattc
    10441 tggcgcttat tcgccacacg cggggcaacg aagtcctgtt tattccggtg ctatttgtcc
    10501 tcttttcgtt agggggcgcc gtatttggca tgggcgaaga ggcggtcgcc tttgcaatta
    10561 tcatagcccc gctgatggtc aggctgggct atgacagcat taccaccgtc ctggtgacct
    10621 atatcgccac ccaaattggc tttgccagtt cgtggatgaa cccgttttgc gtagtcgtcg
    10681 cccaggggat tgccggcgtg ccggtacttt ccggctccgg gctgcgtatt gtggtctgga
    10741 ttgtcgccac gctgattggg ctggttttta cgctggtcta cgcctcacgc gtgaaaaaga
    10801 atccgctgct ttcccgcgtc cacgaatccg atcgctattt ccgcgaacag caggatgaag
    10861 tcgtccagcg ccctttcacc ttcggcgact ggctggtact gctggttctg accggcgtaa
    10921 tgatttgggt cgtctggggc gtgattgtcc acgcctggtt tattccggag atcgccagcc
    10981 agtttttcac catgggcgtg gtgatcggcc tcatcggcgt tatcttccgc ctcaacggta
    11041 tgacggtcaa cgtgatggcg tcctcattca ccgaaggggc gaggatgatg atcgcgcccg
    11101 ccttgctggt gggttttgcc aaaggcattc tgctgctggt cggcaacggc gaagccgggg
    11161 aacccagcgt gctcaatacg ttgcttaaca gtatcgcgca tggcatcagc gggcttaata
    11221 atgctatcgc cgcctggttt atgctgctct tccaggcggt atttaatttc tttgtcacgt
    11281 ccggttcggg ccaggcggcg ttaaccatgc cattactggc gccgctcggc gatctggtcg
    11341 gcgttaaccg tcaggtgact gttcttgcct tccagtttgg cgatggcttc agccatatta
    11401 tctatccgac atcagcttcg ctgatggcca cgctgggcgt gtgccgggtc gattttcgca
    11461 actggcttaa agtgggggcg tcgctgctgg gactgctgtt tatcatgtcc agcgtggtcg
    11521 tgattggcgc gcagatgatg ggatatcatt gatccaaaat gccggatgag catcagcgcc
    11581 atccggcaat atctccatga ttaaagcagt gatttcgcgg cttctacaat cgctgcggcg
    11641 gtgagtccgt actcttgttg taagaaatcc tgcgttccta cctgcccata acgctctttg
    11701 acgccaacac ggcgcatcgg caccgggcag ttttccacca gcacttccgc taccgctgac
    11761 cctagtccat tatggatact gtggttttca cacgtgacga tacgccgcgt tttttccgcg
    11821 tagtttttca ccaacatgcg atcgataggc tttaaggtga acatatcaat gaccgcagcg
    11881 ctcacgcctt cctgctccag ttggcgcgcc gcctccagcg cctccgccac cataatgccg
    11941 ttggcgataa gtgtaatatc atcgccctcg cgcagtacgt tgcccttgcc aatggtaaag
    12001 gtagagcctg gcgcatagat actcgtcgcc tgcttacgga tggtacgcag ccagtaaaaa
    12061 ccgtccaggt ccattagctg gcgtaaaata ttcgcgaaca tcaccgcatc cgtcacctcc
    12121 agtactacag agtgcgccag cccgcgaaca atccccatat cttcaaaaga catatgagtg
    12181 ccgccgttat ggcacgccgt cactccggca tcggaggcga tcactttgac gttgttacgc
    12241 tgataatcca gcgccataaa gagctgatca aaacagcgac ggctggcaaa agcggtaaag
    12301 gtatgcacaa acggtttgcg accggtcagc gccagtcccg ccgccgtgcc aatcacattc
    12361 gcctccataa taccgcagtt aatgacatgc tgcgggtagt cacgcgccac gctgtccatc
    12421 gccatcgagc tcattaaatc agcctcaagc gcaataattg ggcttccggc ctcaatctgc
    12481 ccggcgacaa aaccggcata aactttgcgc atttcgatat cgtctttaag ccctgcgggc
    12541 gcaagcttaa tcatgcatga cctccagttg atgaatggcc tcattgagcg tctgcttcat
    12601 gccatccgtc aggcgtaagt ggtgagaatt cgttaactgc tccaggcatg gcaccccctg
    12661 ccctttaatg ctgtcaagga tcacaacccg tggccgggca tcagcgggcg gcacaggctg
    12721 aaccaccgcc agtagtccgg cgatatcatc gcctttgacg gtgacgacat cgaaaccaaa
    12781 cgcgcggaat ttcccttcca gatcgaatgg attgataatc tcctccagct cgccgtcaag
    12841 ctgttgtttg ttccagtcaa tgaaaacggt cagattattc aggcggtggt gggcaataaa
    12901 ctgaaacgcc tcccagcact gcccttcatt cagctcccca tcgccgacaa tgcaaaatac
    12961 ccggttgggt cgccgcgcca gtttatgcga caacgccatt ccgcccgcaa tagagatgcc
    13021 ttgtcccagt gagccggtcg tggcgtccac gccgtgcgtt tttagccgat ccggatggct
    13081 gggaagacgg gtgccgttct ggttaagcgt attcagctct tcgcgcggga aatagccttt
    13141 aatcgccagg gtactgtaca acgcggggcc cgcatggcct ttcgacagta cgaagtaatc
    13201 gcgctccggc cagtccgggt cggcagggtc gattttcatc accgcgccgt acagaaccgc
    13261 cagagtctcc actaccgaca tgctgccgcc atagtgacca aagccaagat ggtttaagga
    13321 tttgagcgtg gcgacgcgaa tgtcgcgcgc cagttgggtg atttcggtta cgttcattct
    13381 ttcgctccgc tattttcctg cacttcggca gtcgcttttt tgcttttggc caacacgttg
    13441 tacgccacca gtagcgcgaa tagcgccacc accagccccg tgatagccat cggcgacaga
    13501 taacgcgcca ggttgcccag caaaataccg attacgccaa agtcagcatc cgagaacgtg
    13561 gtattggcga agccgatcgc gccgagaacc ggcagtaaca gcactggcag gaaagtgatt
    13621 aatagaccat tagcaaatgc gccgatcatc gccccgcggc gaccgccggt ggcattgcca
    13681 aagacgcctg cggtcgcgcc ggtaaagaag tgcggcacaa cgccaggcag gattaacaca
    13741 agcttcatct gtccaagcag gaacagcccc accagcccgc cgagaaaact gaacaggaag
    13801 ccaatcagta ccgcgttagg ggcataggga tacaccaccg ggcagtccag cgccggacgc
    13861 gcgtttggca ccagtttttc tgaaaagccg gtaaaggccg gaacaatttc cgccagaatc
    13921 agacggacgc cttgcagaat gatgaatacg ccggcggcga aggtgattgc catgataatg
    13981 gcgtacacca gatagttttg cccgccgcta aacgtcgctt cgacatactc acgccctgcg
    14041 ctgactgcca tgatcagata gataatcatc atggtcagcg aaatcgagat agaactgtcg
    14101 cgtaaaaaac tgaggttttt cggcaggttc atctcttccg tggagcggga gcctttacca
    14161 cacaggctgc caatccagcc ggaaagcaca tatcccaggg taccgaagtg accaaacgca
    14221 atgtcatcgg taccggtaat ccgcctcata taacgttggg ccaacgccgg gaagaaggcc
    14281 atcaccagcc ccaggattag cgatccggtg aagaccagcc ctacgccctc aaaccccgcc
    14341 acggtcagga ttacgccaat catacaggcc atgtaaaagg tgtgatgccc ggtcaaaaag
    14401 atatatttaa gacgcgtaaa gcgcgccacg acaatattgg ccaccatacc aaatgccata
    14461 attaacgccg tggacgcgcc atatttttcc agcgcgattg agactatcgc ttcattatta
    14521 ggaataatac cctgaatatt aaaagcgtgt tcaaacatac cccctagcgg gtttaatgaa
    14581 cccaccagta cggttgcgcc accgccaagc acaataaaac ctaaaatggt tttaatcgtg
    14641 ccttttacca catcggaaaa cgcttttttc tgcgccacca gaccaatcag cgcaattaac
    14701 cctacaagca ccgatggcac ttttaaaata tcaacaacaa aattcagcgt ttcaaggata
    14761 aacatatcca cctcgccagc aataattatt gtttagcgaa ccatgcgcgc agctgcgttt
    14821 ccagttcgtt gatgtcgatg atgttattga tcaccaccag ttggctttcc ggtacgctgg
    14881 cgctggccgc gatatctttg gccattacaa aaagatcggc agccccgggt gtggccgatg
    14941 agagatcgga gtgttccact tcagcgtcaa tattgagttt ctttaatact tttttaatgt
    15001 tcatttctac cataaaacta ctacccaggc cggaaccgca aattgccatg attttcatta
    15061 ttgtcacctt ttaaaagtag agttggtctg catcacgcac gggcgcaatg ttatttaccg
    15121 caagaaaatg gaataaaatc agaaacggtc aataatcgtt ttaatgtcct ccaggttttt
    15181 tgcctgatgt aatttttcca tatctacatc actggaaaat aattccgcca gagccgatat
    15241 catttcgata tgactgtgct tatcaggcgc cgccagcata ataatgatgt caaccggatc
    15301 gaattcgtct gcgccaaatg aaacgccgcg ctgtagtttc agtaacgata aacctaaccc
    15361 tttcgccccc tcttccggcc tcgcatgcgg catcgctaac cctggcgcta atacataata
    15421 cggcccaagc ttttggtgct gctgaacaat cgccgtaatg tattccggtg cgataacacc
    15481 tgcgtccagc aggggtttgc cgcaaatttc cagcgcctgc ggccacgttt ccacgctctc
    15541 ccgtagcgtg atggttgcgt cagataacca ggttcccagc atgttattcg cccccacggt
    15601 gtatgaaatt atgaacaaac tttattcaag ccattcgata ttagctgcga tcgttatcac
    15661 aaagatagcg ctaccagcga ctattactca gaattgtgat agcgctatca aattaaaatc
    15721 atggtgtgaa atcacagcaa aaaagcggat ttaaggcgta tactgccagt catgcgaagc
    15781 aaagaacgac aataaaaaag catctcaaca tgttgtaatg acgcaggaat ttgtatgtcg
    15841 ataccccgta aacggcgcag taccggtaaa gtgactatcg ccgatgtagc ccaacttgcc
    15901 ggtgtaggca cgatgaccgt atcacgagcc ttacgcacgc cggaacaggt ctctgataaa
    15961 ctccgggaaa aaatcgaagc ggcagtgcat gagctgggct atatgcctaa tctcgccgcc
    16021 agcgcgctgg cgtctgcctc ctcgcacacc atcgcgatgg tcgtaccgaa ccttgcggaa
    16081 gcggggtgtt ctgaaatgtt cgccgggctg caacaaattt tacagcccgc aggctaccag
    16141 ataatgctgg cggaatcgca gcatcgcgtg gaacaagagg agaagctgct cgaaacgctg
    16201 ctggcttcca acattgccgc ggcgattctg cttagcgtcg aacatagcac taccgtgcgc
    16261 cagtggctga aaaatgcctc tatcccggtg atggagatgg gcgcgattcg cagcgatcct
    16321 attgatatga atatcggtat tgataacgtt gcagcaatgt atgagctgac ggaaatgctg
    16381 attcagcgcg gttaccagaa tatcgggctg ctatgcgcca atcaggagca gtggattttt
    16441 cagcaacatc tgcacggctg gtacaaagcg atgcttcgcc accatatgtc gccaaaccgg
    16501 gtgattaatg ccgccttgcc gcccaatttt tctaccggcg cgtcgcaact gccggagttt
    16561 ttactagcat ggccggagct ggacgcgctg gtatgcgtat cggatgagct ggcctgcggc
    16621 gcgttatacg agtgccaacg acggcggatc aaagttccgg acgatttagc ggtggtcggg
    16681 tttggcgata gcgatgtcag ccgggtctgc cagccgccgt taaccaccat ggccgtaccg
    16741 caccgtaaga ttggcagtga agccggacgg gcgctgttgg aaaggttaaa tcagggaaac
    16801 tggagcgatc gaaaatctat cgcctccagt ttatgtatgc gggaaagctg ctaaaacgct
    16861 tattccgtct cttccggttt ctcctgaagc gcggcttcgt ttttggcgtt gcgggtcatc
    16921 cacagcgcca gcgctttgag cgagtccggc gtaaattcat cacagcgcgc ggtgatctcc
    16981 tccggagtca gccaacacac ttcgctgact tcatcttcct gaagcgcgaa aggcccgtgg
    17041 gaaacgcagc taaacagcgc gccccaaacc cggcaatgtt ggtcttcaaa gtaaaacaga
    17101 ccgtgttcgg caaacggcac gcctgcaata cccaactctt cttccgcttc gcggcgggca
    17161 gattccagta gctgctcatc agcctggacc acgccgcctg cggtagcatc taacataccg
    17221 ggcaaaaaat cttttgtttc ggtacgacgc tgcaccagaa ttttacccat accatcatga
    17281 acgacgatat acgtcgcacg atgccgtaag cgttgcgcac gcatctgttc ccggctggac
    17341 tgtgcaatga cttcattgtc ttcattcaca atatccaccc attccgtact tgccaaacga
    17401 cgctgttcca ccatcaggaa accttcttat ttctggcgct cttacggcgc atttacgttt
    17461 gtgaggtaaa ttacgagtta attgcaacct gcgcaatgat actttgatca ttgagtgcga
    17521 ttacgctcaa cacattatca tccagaatac cgtagcttgc tgcatacccg cctttcggga
    17581 tgctcactga cccaggatta aagtgataca gtccttcctg ctgttgcgcc accggcagat
    17641 gcgtatgacc atagaccaac acatcgccag tatgcagagc gggcagattc gtcggcccga
    17701 agaggtgccc atgcgttaaa aatagccgcc tctcttgcgt caatatttgc tgccacggtg
    17761 cagttatcgg gaaatgcagc agcatctgat ccacttcgct atcgcagttg ccgcgcacgg
    17821 caatgatttg cgtcgccacc gcgttcaggc gttcggcaac ctgggcgggc gcatagcctt
    17881 caggcagcgc attgcgcggc ccgtggttaa ggacatcgcc taatatcacc agccaacgcg
    17941 cgccgctttg cgcgaaccgc tcaagcacgc gttccgtggc gggtaaagaa ccatgaatgt
    18001 ccgatgcgaa catcagtttc atcgctcact cctcattgtg aaaaacggcg ttatgatact
    18061 ggaatatgaa tagattttca gcctgaacgc ttcgaggaaa gcgcaataaa acgctgtacg
    18121 gaagcacgct gccactgaaa tgtcgcatac gccgccagcg acgccggcac gtcatcgcca
    18181 tgcagcacca gacgattgat catcaatgcc agatcggtat cggcaatgca ccattcacca
    18241 aataaatttt gcgtcccctg ccccaatagc gcttcagccg tcgcaaacag ttttgccgca
    18301 ctggcttttc cagcctcgct tagcggcgct tttttcgccc cggcaaacac cacgtcggta
    18361 ggccgttctt cgcgaagcgg cagtaaatcg ctgcgtagcc acgcctgaat ctgtcgcgcg
    18421 cgggcgcgtt tttgtaaatc gtgcgggtag atacgctccc actgcggcgg cgcgaaacgc
    18481 tcctccaggt attccgcaat agcggacgac tcgctcagct caaaattgtc ggcctcaagc
    18541 accgggacgc gctgcgtcag cgcatatccc cgccagccag gttgcagatg ttctccctag
    18601 tccagatcgc gggttttcag agtaaaggaa agcccttttt cttgtaatgc cacccaggcg
    18661 gacaagacgt agggagagaa aaagttcgca tccgaccaca gcacaataac aggcttactc
    18721 ataatgtcct cttgagggcg tattaggttt cttcccaaaa tatagcgtct ttcgcctgct
    18781 gtcacctgat gaaaactcac acacatcagg aggctttcta tacttaattc agcccagact
    18841 ctttacgcac atgcaggagc caaaatgatt gacctttact acgcccccac gcccaacggg
    18901 cataaaataa tgctgtttct ggaagaggcg gagctggcgt atcgtttgct aaaagtagat
    18961 atcagcaagg gcaatcagtt tcgccctgat tttttggcta tctctcccaa taataaaatt
    19021 cctgccatcg tcgatcacgc cccggcagac ggcggtcaac cgcttagtct ttttgaatcc
    19081 ggcgaaattc ttctctacct agcggaaaaa agcggcaaac tgcttagcgg ggagctgcgt
    19141 gaacgccata ccacgctgca atggctgttc tggcaggtcg gcgggttagg gccgatgctg
    19201 ggccagaatc atcactttaa ccactttgcg ccacaggcca tcccctatgc gattgaacgc
    19261 tatcaggttg aaacgcaacg cttatacaac gtcctgaata aacgcctgga aacctccccg
    19321 tggctgggcg gcgaccacta cagtattgcg gatatcgcca gttggccgtg ggttaacgca
    19381 catcagcgtc agcgaatcga tcttgatact tacccggcgg tgtataactg gtttgaacgc
    19441 attcgcacgc gtcctgcgac agcgcgcgca ctgttacaag cgcaactgca ctgtaacagt
    19501 acgaaagcgt aacgcggtag catacatcat gtatgatgta gaggtgtata cacggaaaac
    19561 ctgcgtccgg cacccttatt cgtattaaaa acctgacatt agggaagagg aaatcctccc
    19621 tactctggag gtcatatgca gattctgatt accggcggta cgggcctgat agggcgtcat
    19681 ctcattcccc ggctgttaat actggggcac caggtgacgg tcgttacgcg caatcccgat
    19741 aacgcgcgtc agattctcga ttccagagtg acattatgga aagggctggc ggaacgtgag
    19801 cacctcaatg agattgatgc catcatcaat ctggcgggcg aaccgattgc cgacaagcgc
    19861 tggacgtcgc aacaaaaaga acggttgtgc caaagccgct gggctatcac gcaaaagttg
    19921 gtggatttaa ttcatgccag cgctacgccg ccctcggtgt tgatatccgg ctccgccacg
    19981 ggctattacg gcgatctggg cgacgttgtc gtcactgaag atgagccgcc gcacaacgaa
    20041 tttacgcata aactttgcgc ccgctgggaa cagattgcct gtcgtgcgca gagcgaccag
    20101 acccgcgtct gcctgctgcg taccggcgtt gtcctggcgc cgcaaggcgg gattctgggg
    20161 aaaatggttc cgccgtttcg cctcggactc ggcggtccgg tgggtaatgg tcggcaatat
    20221 ctggcctgga ttcacattga cgatatggtc aacggcatcc tgtggctgct ggataacgat
    20281 cttcgcggtc ccttcaatat ggtctcgccg tatcccgtcc ataatgagca gtttgctcat
    20341 gcgctgggtc gcgcgctgcg ccgcccggcg attattcgca ttccggcgac ggcaattcgc
    20401 ttattgatgg gagagtcgtc agtgctggta ctgggcggac agcgggcgct gccaaaacgg
    20461 cttgaagccg ccggattcgc atttcgctgg tatgatttag aagaggcgct ggcggatgtg
    20521 attcgctaat tcccaaagcg ccgtatcctg cccggtaagc gatgcgccgc cgggcttctt
    20581 ttatttcagc gagcctttca ggaattgctg taaacgcggg ctttgcggat tgccgaacac
    20641 ctgctccgga ttgccctctt cttcaatttt cccctgatgc agaaaaatca cgtgcgaaga
    20701 gacatggcgg gcgaagccca tttcatgcgt gaccaccacc atcgttttgc cttcttccgc
    20761 cagttgttgc atgatgcgca acacttcgcc gaccagttca ggatcgagcg ccgatgtggg
    20821 ttcatcgaac agtaaaacgt caggttccat cgccagcgcg cgcgcaatag aaacgcgctg
    20881 ctgttggccg ccggagagat ggacgggata tttgccctga gcgcgctcat caatccccac
    20941 cttcgccaga tatttcaacg cccgctcgcg cgcgtcgtgc ttgcttaatc ccagtacctg
    21001 aatcggcgct tccatcacat tttccagcac cgtcatgtgg ttccagaggt taaagtgctg
    21061 aaacaccatc gtcaggcggg tacgcaacaa gcgtagctga tttttatccg ccactttgag
    21121 ctgcccgtct ttgtcgcgca ccagattaat gttctgaccg ttcacgataa tcgcgccttc
    21181 gctcgatttt tcgaggaagt taatgcagcg caaaaaagtg cttttaccgg aaccggacga
    21241 gccgataatg ctaatcacat ctccggcgcg ggcctgcagc gatacccctt tcagcacttc
    21301 atgaccgccg tagcgtttgt gcaaatcgat aacgtgtaat ttattttctg acatcatgtt
    21361 actcgaatta tttagaggac acgtgctgca accagcgtct ttccgcccgg cggaacaggc
    21421 ttatcaggac atacgaaatg agtaaataca acacggcggc aatgccaaac gcggtaaacg
    21481 gctggtaagt cgctgagtta atatcgcggg cgattttcaa caaatccggc accgtcgcgg
    21541 taaacgccag cgccgtagag tgcagcatta aaatcacttc gttgctgtag gcaggcaagg
    21601 cgatgcgtaa tgccgacggc aaaataatgc agcgatacat tttaaatgac gagaagccat
    21661 acgctcttgc cgcttcaatt tcaccgtgcg gtaccgaacg aatcgctccg gcgaaaatct
    21721 ccgtagtgta tgcgcaggta ttcagcgtca gcgccagtac ggtacagttc agtccgctgc
    21781 ggaaaaacgc gttaagaaga tcggtgcctt tgactatctc cagcgtatac atccccgaat
    21841 agaacaccag tagctgtacg tacagcggcg tgccgcgaaa aatatacgta aacagccaga
    21901 tgggaaaacg gatgaattta ttactggaaa cgcgacccac cgccagaatc accgccagaa
    21961 gaccgcccat caccaccgat gaaattaaca accacagcgt aatcgccacg cctgtaaaac
    22021 gatagccatc cgtccacagc agggatttcc agtactcctg aatgatctca atcacaaatc
    22081 ggccctcttc acgcctacgg aatagcgacg ctcaagtaag agcagcacac cattggaaac
    22141 ggtggtaaat accaggtaga taagtccaca gaccacggca aaatagaaag gctcccaggt
    22201 gcttttaccg gcaagctgcg tggctttgac gacatcttcc aggcccagca gcgacaccag
    22261 cgctgtcgct ttgagtatca cctgccagtt attgccgatc cccggcaggg cgtaacgcat
    22321 catcgccggg aacataatcc gccggaaggt ttgcccgtgg gtaaaaccaa aggccgtcgc
    22381 cgcctcgata tggcctttcg gtaccgccat aaacgcgccg cgaaaggttt cggtaaaata
    22441 ggcgccgtag atgaaaccaa gggtgataat accggccacc atcggatcaa tatctatctg
    22501 gtcgataccc agcgaatcgg tcaccacgtt aagcgcgatt tgcaatccgt aaaatatcag
    22561 cagcattaat accagatccg gcaccccgcg aatcagggtg gtgtaccctt caaaaataag
    22621 ccccgttacc cggttttgcg aaagcttcgc ccccgcgccg acgagaccga taagcacggc
    22681 cagcaccacg gaactgagcg ccagttccag cgtgacgatc gcgccctgta aaattacgcc
    22741 tgaaaacccg tacaacatgc agcctgtcct gttgtgtgtg gtgaagtaag aagcctcttt
    22801 tgcatttttg cctcacatca cgccggatgg cggctgtgcc ttgcccggcc tacgatgctc
    22861 cccgtaggcc tgacgcgcac agcgccctca ggcaatgcag acagtcaata ttctttgggc
    22921 tttatctgca ccgacggtga ttaaccgcca taaacatcaa aatcaaagta ctttttcgcc
    22981 aacttttcgt aagtaccgtc agcacgcatt tcagcaaagg ctttgttcag cgcttcgcgc
    23041 agctcgttat cctctttgcg cagccccata ccggttccta cgccgaataa cttctcatct
    23101 ttcaccgccg ggccgccgaa tttatagtct tttccgatgg gctgtttaag gaaaccttcg
    23161 ctggccgcga cctcgtcctg gaacgccgca tcaatacggc cagccgtcag gtcggaataa
    23221 atgttgtcct gcccctggta agagacgatc tcaatccctt tcggcgccca gtgctcattg
    23281 ccgaaggtct cctgcgtcgt cccctgtagc acgccgacgc gcttgccttt cagcgacgcg
    23341 acggtcggct gaatatcaga gttcttcgcc accaccagac gggaatcagc ggcgtaaagc
    23401 ttgtcggtaa acgcgatttc ctgctggcgc ttttcagtga tggacagcga ggacatgatg
    23461 gcatcaattt tcttcgcttt taaagacgga atcagcgcat ccagcgggtt ttccacgaac
    23521 gtacactgtg tgttgatacg gttgcacagt tctttggcca gatcgatatc aaagccgacc
    23581 aattcacctt gtgcattttt ggattcaaac ggtgcgtatg taggatcggt accgatgcga
    23641 atcttttgtg gaatagcggc aaatgctgcg gtagcgctgg aaaatgccag caccagagaa
    23701 agggataacg ccagtttttt cataactatc ctcaacagac tgtctttcca ggagatcttt
    23761 acagatccga tgcgactatc gtgccattaa tcaggccgac aaggcaaagc attctacctt
    23821 gtcagccggt ttattttgca taaaaatcga ttaagtatgc atttatgcgc ctgttccgca
    23881 acggcttatg caccaaaaag gtgcaaaaca tctattttgc accgtgatag ttccccagcg
    23941 cggcgcgtta tccccttccc tcaatcgccg tagacattaa aatcgaagta ctttttggcc
    24001 attttgtcgt aagttccgtc ctggcgcagt tcggtcagcg ctttatcaaa cgcggctttt
    24061 agctcggtat cgtctttgcg cagcccaacc cccgtcccgt cgccaaaata ttttttatcc
    24121 ttcacggaag gaccggcaaa cgcatactct ttgcccgctg gctgcttcag gaaaccttcg
    24181 ctggcggcga cttcatcctg caatgcggca tccagacgac cggcggttaa atcggaatag
    24241 ataagatcct ggttggcata agccaccaca tccacacctt tagtgcgcca gttatcattg
    24301 gcgtaagcct cttgcgtgga cccttgcagc acgccgacat gcttgccttt cagcgattcc
    24361 agcgtcggct gaatgggaga cccttttgcc gcaatcaggc gtgaatccgc cgcgtaaagt
    24421 ttgtcggaaa acgcaatttc ttgctggcgt ttatcggtaa tagagagcga tgaaataatg
    24481 gcatcgattt ttttcgcttt tagtgaggga ataagcgcat caaagtcgct ggcgacccag
    24541 gtacatttca cctgcatacg cttacacatt tcattaccga gatcgatatc aaagccaata
    24601 aagtcgcctt tggcatcttt cgatgagaaa ggcgcgtagg tggtatctgt tccaatacga
    24661 accgtttgcg ggagcgcggc gtaactggcc gccgtcgcgc ccagacctat cagcaaagac
    24721 aaagcgagaa cggtcttctt catacatacc cctcaagtgg cgtcattttc ttatgtttta
    24781 cgtggcgttg tgtgtttgca gactttttca tgcaggtctt atgccatttt cacgtcagca
    24841 aaacgattcg acgttaaatt tgttaataaa acgttgcaat attgtcctga tgttgaagat
    24901 agcaggtatg acggttgaac cgcagcgttt cggcggcttt taacgaatta aatgttgagg
    24961 atatgatcgc ggttacaaaa ttgccctgaa acagggcaac agggacaata atgcacgcta
    25021 aacagacaac gctatgcgcc ctgccagcga acaaaaaggt cgtgcggaag ggggatgtca
    25081 aattgatcca acactcggtt aaccgtttga tttataacat catctaacgt ctgaggaagg
    25141 tgataaaaag ccggaaccgg cggcataatc accgcgccta tctcagcggc ctgggtcatt
    25201 aaacgcaaat gcccgatatg cagcggcgtt tcgcgcacac acagcaccag aggtcgccgc
    25261 tcttttaata tcacatccgc cgcgcgggta agcagtccgt cagtataact gtggacaatc
    25321 cccgacagcg ttttaatcga acagggcagg ataaccattc ctgccgtcgg gtaagagccg
    25381 gaggaaatgc tggcggcaat gtcgcgcgca tcgtgcgtca catcggccag cgcctgcacc
    25441 tcgcgcagcg aaaaatgggt ctccagcgcc agcgtttgcc gggccgcctg gctcatcacc
    25501 agatgcgttt ccacgctatc gacatcgcgc aaaatttgta ataagcgcac gccataaatc
    25561 gctccgctgg cgccgctaat acctacaatg agtcgtttca tgtcctctta ccgtttacga
    25621 gcgccgttca tcccactgtg ttacgtaacc ggctcaaagt gggtctgaag agataccatg
    25681 acaaaagaat ccctatcata aaagccagct caaccaacat tatcactact ccctgctcac
    25741 taaactaggt gccgaccata atggcaaaat tggtgataat gacaaatcgg gccgtccagg
    25801 gaaaaagcgg cgatcgatag cgtagcaaat cgctggcgta cgtgccatta cgcaccgatt
    25861 gtcggaagcg atactggcac catccgatgg ttatccatgc caggcaaccc acctgcccgg
    25921 tactggcgat cagatataaa taaaattgct gtgcgggaat atagcgggtc agcaacgaca
    25981 ccaacgccag caaggccgtg attaaaatag catacaccgg cacgccgccg ccgttcgttt
    26041 taccaaagca ggctggcgca aagcgatcgc ccgccataga ccacagcata cgcgaactgg
    26101 cgtaaatggc cgagttagcg gcagaaaccg cggcggaaaa gatcaccagc gtcatcagcg
    26161 tatccgcccc cggaatgccc gcgtgggaga atacccatac aaagggactt tgtccatttg
    26221 gcgtcagttc atgcggatag atcagcgcca gcaccgcaat cgccaggccg taaaacaaaa
    26281 tgattctgag accgatcccc aggatcacct tcggtaaaat aatgtgcggc gattcggtct
    26341 cccctgccgc atttccgacc agttccaccc cctggaagga gtaaatcacg atcgtcatac
    26401 agaccacaat ttgctcccaa ccgtggggaa accacattcc gtctgttttt aacgtcgggt
    26461 gccagtcact atggcccatt agcgagtaga tcatgacccc gcccgcgcag ataaacagca
    26521 cgatcgcgaa gaccttaatg gccgaaagcc agtattcgca ttcgccaaaa ctttttgcgg
    26581 aggtgagatt gatagccgtc aggatgagca gaatcgccag gcagaacata tataccggaa
    26641 ccgcggggaa aaactggtga gcaataaacc ctgcggcagt gaggtcggct gccagggaaa
    26701 agacccagct aaaccagtaa agccagccaa tggtatagct ccagcaaggt gacggcataa
    26761 acatcagcgc gtaatgttga aatgaaccgg agtgaggaaa ggcgcatgat aattcgccaa
    26821 gacacatcat cgtcgccagc ataatggttc cggcaaacag ataggccagt aaggttcccg
    26881 ccggcccgac gctgcttaac ggttcggcaa tgccgataaa taagccggtg ccaatcgtgc
    26941 cgcccagcga catcatcagc aggtgccgct tcttcaggtt acgccgcaga ccgccttcag
    27001 gctctgctgg cggagattgt tgcagggtat ccatcgttac tccctgtctt tcgtgaggtc
    27061 aaagatgccg ccgcgacata gccgcggcgg ttatgcgtta acgcgtaaac ctccaggcga
    27121 cgcctttggt ctggcaggcc attaacaggc ccgtataatc cagctcaaag cgaaccacat
    27181 cgcctacttt tagcgactga cgacaatctt caatatccac cagcgtatga tcgctggttt
    27241 gccctaagat agtgatagcg tcgtcgcatg gcacacagtt atccgacggc acatcctgac
    27301 gaccaaacgc cagcaatgcg cgtcggcgta tgccacgatc gacaaaggtt ttactttgca
    27361 aaaaggcatc gacgcccagc tccccgaccg ggacggtcgg tttactgttc agttcgatga
    27421 tttccgcttc caggatatac atatcggaac aggctttatc gaccggtttt gcggagtggt
    27481 gaaattcatt caggtatttc atgtccacat attcaatgcc gaattcatgc agtccgccga
    27541 tgcgcagatg attcagtccc tgcggccaga tacctttatc cagcaggtga tagctggtgc
    27601 agtttcccgc agaaagccgc cggacaggaa taccgctgtc agcttccagc cgggcggcca
    27661 gcgccagaaa atcctcgcca ttttttaccg ttggcaacac ggtgccgtaa caattaaagt
    27721 tggtgcccag tccatataat tccagaccgg gcagaccagt aatcagagtc acggtctcaa
    27781 gaatgcgttg atattcacca aaccagatac cctcgcgtaa atcgcccata tccaccatca
    27841 gtaatacctg atgcgttttc ccctggcgtt gggcttcttg cgataatgcc cgtaatacca
    27901 ccggctcgct atttaaacta atatccgcgt agcgcaccac atcttcgatt tcactcagac
    27961 acgggctgcg taacaggcag gtcgtacatc ctgtctcgcg tatttttttc aaattatagg
    28021 ttcgtgattc agcaataacg gtaattccgc cgtttaacac cgcctgcgcg gtttccacgc
    28081 agccgtcaaa aactttattg acagccatca cgtcaatacc gctgcttgcc agcagagctt
    28141 tttccgtgcg tgcgttttct tccagcttgc gtagatttat ttccagaact ggcatataca
    28201 ttttattttc ctcccgccat gcttaaacgg gcattacgtt tctgcgcccg atggtaaatg
    28261 tactccgcga cgacaaccgc cagcacggct ccgccaataa ttttcccggc gtactggaaa
    28321 tatccgccca tatcaatttg agaaggcgga ataaataaca gcgcaacggc aaaggcgata
    28381 gaaagaaagc ccagcgcggg taaaatagcc ggtaaaacct tgcccggaat tttaaaactt
    28441 cttggcgtat ctggctgagt cttacgtaaa cgccagaacg ccgggaacat caccagataa
    28501 ggaataaaat aggtgatggt cgttagcgcc gttaacatcc agtaagccgc cgcaacgctt
    28561 ggcgaaataa aagtcgaaaa acacaggacc gtgacaataa tcgcctgtat agtcaaggca
    28621 aaggcgggcg ttttccacac cggatgtaat ttgccgattc ggtcccccag cagattatct
    28681 tcacgcgagg cttcctggag catataaatc ggccccacca gccaggagtt aatctgcccg
    28741 agagcgccaa aaaacataca gatggccata acaggaatta accacggcat atgcagcgtg
    28801 tccgcagcag catgcatagc ctgcatgacg cctgccacga tgtcggtttt cccggcgggt
    28861 aaaagcgtat ttagcgccca ggtgccgacc atatagatcc caacgataac ggcggcagag
    28921 acggccatcg ctcgcggaaa atcacgctgt ggattacggg tacgcccggc aatcatcggg
    28981 gcgacctcca gtccggcaaa cgcaaacatc atgctggata agaaaacgat cgtatcccag
    29041 tgtccgagat ccggaatcca gtttttcgct gtagtgtagt ccgtctgcat ctggtgtccg
    29101 gtacatagcc ataccaccgc cagcaaaatg aggatggcgg agggaataaa tacgccgcac
    29161 caggcgctga tgctattaat aatttttgtc cattccatcc cgcggatatt catcagcgtt
    29221 aatagccaga aaattaccgc ggaaccaata ccgataaacg ctttattttc cgccaggccg
    29281 ccgccgatca tatagcccaa cgcggtaaag ccgaattgca gcattaatgg gaaaaacagt
    29341 acgcaggaaa agagaaaaca aaccacgaca atccatgcaa tacgtttacc aaatgcctct
    29401 ttaatccaga caaatatccc gccatctttc ggccagccgg ttgacagctc gccgcatacc
    29461 atcgctaaag gaaaaaacaa gcagaatgcg gctatcaccc atagcaacat ggccgatgcc
    29521 ccgtaaggcg ccacgttagg gatttgccgc aaactcagaa tagcgatgac attcataaag
    29581 acaatgtctt tgatgccaag taagccagaa ttcgtgttac tcatggccat ctcctgttat
    29641 gcattcaggc atcactgccc tcttcttatc atctgacgac gggcttcagc atgaaactga
    29701 agcccaaaac agtattaata aatgtcgtac ttgaccatat cttcgtaact gtcttcccga
    29761 cgaatcagac gcgtctcacc atttttatcg atcatcacca cccccgtgcg cggacggttg
    29821 ttataaacgg tttgactttc aatggtgtat gccccggcat caagaaacgc gacaatatcg
    29881 ccaacatgag tctccttcgg cagtaaaaac tcttcgcctt tcactcccat gtggaaataa
    29941 tccccgccat cacacagcgg cccggctaat tttatccagg cgtcgtgcgc tgccgtcatg
    30001 cgagaggcgt tatagacata aaagaaccag tcaaaatgct ggctatcaga gagtacgctg
    30061 taaccagcat cgacaaattt ccattcaacg tggcattcca cattgccgtt aagatcgtaa
    30121 tttgttttac gtttttcgca ggagacttcc gtcagtaaaa ccgccgccga cccggtcact
    30181 ttacgtcccg gttcaataca tatttccaca tcggtacgcc atttatgcac ttcgcgaatg
    30241 accgcatcgg caaaatcctg ggcggtaata ccggcataca tattatcttt taacgggtcg
    30301 ccattctcgt cgtcatattt atagggaacc ggaattccgc cgcccacgtt gatcaaatca
    30361 aatttaatac cgagcacctc ttccaggcga cgggattcat ccaccagcac tttagtcgct
    30421 tttgcgaaag gctctgactc cggcacctga tcgcccacat gcatatgcaa gccgcgtaaa
    30481 tgcacataag gcatcgccag aatgcggcgg caggtttctt ccgcctgttc caggtcgaga
    30541 cccgacttcg catggaaagc ggtaaccagt tccgcatgcg tcgccgaggg aacattcggc
    30601 tctacgcgga cgcaaacatt ggcgactttc ttcagcttgc gagagatggc atcaatatgt
    30661 tccagctcat acaggctatc aacattaata agatacagat cgttggcgat ggcatattcc
    30721 agatcggcag gctttttcac cacgccgttg aagacgatct gatcgccgcg aaagcctatc
    30781 tccaggcact tgcgaacctc atattgtgag tttgcctccg cgcaaattcc ggcgtcacga
    30841 atggctttca acacccccat gaccgagcag gtttttgacg caaagaaggt tttggtattt
    30901 ttatgcgccg caaatgcctg ctggatttca tgaatgttac gaataatctc cggctcagaa
    30961 aacacataga acggcgtggg gtactggcgc gccagagcgt ccagatcgac cccttcaaaa
    31021 cacaaatgac cgtctttgtg ctggaaacgg cgatcgccgt tgattacctg ctcacgtagc
    31081 tggttgtaat tctgcataat cgagtcagtc ataacgccct ctgcttaatg tttatggtaa
    31141 aaatccgcat tctttacagg gataaagcaa aaggcatgcc actatttttt atcaaaataa
    31201 tcaattattt ataaaaataa gctgtttctc attttcgtca ttaagtttgc tattcatcat
    31261 aacgacgaaa attcgtcatt tttataatgg caacatgaac aatagatatg aggaatgcat
    31321 gtatggcatc caccaatcag gaactggcct cggcgctcag gatgttttcc cgctttttcg
    31381 atttgattca tcagccgttg gccgtcatta atgagcgtgg tgaatacgtt tactacaatc
    31441 aggaaagcgc ggatctggac ggctacagca ttgaacgggc aatgggaaaa catatgctgg
    31501 atgtctatcc gggcatgaaa gaaacccaaa gtacgatgct ttcatcgtta aaaaaaggcg
    31561 tggaatacat tggccattat caaatttatt acaatgcgcg aggccaggcc gttgactatc
    31621 agcacaccac cgcgtcgctc tatgcaagcg atggcggcat ggtcggcgtt atcgaaatcg
    31681 gcaggaatat gtccggcgtc aggcggctcc aggagcaggt ggtagaactg aaccaactgc
    31741 tgtatgccga tcaccatgag aagcaccatg ccattattac cgaaaatccg gaaatgctca
    31801 gtaatatcgc caaagccaaa cggctggccg ccagtaatat tccggtgacg attgtcgggg
    31861 agacgggaac gggtaaggag ctattttccc gcctgataca tcaatgcagc aagcgggcga
    31921 ataagccatt tatcgccctg aactgcggcg ctctaccgcc tacgcttatc gaaagtacgc
    31981 ttttcggcac cgtgcgcggc gcctataccg gcgcggaaaa tagccagggc tatctggaac
    32041 tggcaaacgg gggaacgctc tttcttgatg agctgaacgc catgccgata gaaatgcaaa
    32101 gtaagctgct gcgattcttg caggataaaa ccttctggcg gctcggcgga caacagcaac
    32161 tccactctga tgtcaggatc gttgccgcca tgaacgaagc gcccgtcaaa ttaattcaac
    32221 aagaacgcct gcgggcagat cttttttatc ggttgagcgt cggaatgttg acgttaccgc
    32281 cgttgcgcgc ccgcccggaa gatatcccct tactggcgaa ttattttatt gataaatacc
    32341 gtaatgacgt gccgcaggac attcacggat taagcgagac ggcgcgtgct gatctgctca
    32401 atcacgcctg gccgggtaat gtcaggatgc tggaaaacgc gattgtacgc agcatgatca
    32461 tgcaggaaaa agacgggctg ctgaaacaca tcatttttga acaggacgag ttaaatttag
    32521 gcgtaccgga aaccgcgccg gagaatcccc ttccctcgtc acccgatccg cagtatgaag
    32581 ggtcgctgga ggtacgggtt gccaactacg aaaggcattt aatagaaacc gcgctggata
    32641 cgcatcaggg gaacattgcc gccgcggccc gtagccttaa cgtatcccgc accacgttac
    32701 agtacaaagt acaaaaatac gctattcgct tcggcgtggt gcgtaattga catcggccag
    32761 cggcatcgcg ccgctggcaa agccattagc cttcgttatg catttccaag ttttccattt
    32821 cgttctggaa cagcaccgct ttggcgtcgt cattacgtaa tgaatccagg aagtcgaggt
    32881 attgctggtc tacgtctttg gtgacatata ccccgttaaa taccgaacat tcaaactgct
    32941 ggatatccgg gttttctgcg cgtacggctt cgatcagatc gttcagatcc tggaagataa
    33001 gcccgtctgc gccgatgatc tgccgaatct catccacctc gcgaccatgc gcgatcagct
    33061 cattggcggt cggcatatca atgccataga cgttggggaa acgaatttcc ggcgcggcgg
    33121 acgccagata aaccttcttc gcgccagctt cccgggccat ctcgatgatc tgctctgatg
    33181 tggtgccacg cacgatggaa tcatccacca gcaggacgtt cttatcgcgg aattccgcgc
    33241 gattagcatt gagcttacgg cgcacggatt tacggcgtag ctgttggccc ggcatgataa
    33301 aggtacgtcc cacgtaacga tttttgacaa atccctggcg gtacggcttg ccgagaatac
    33361 gggcaatttc cagggcgata tcgcaggagg tttccgggat agggatcacg acgtcgatgt
    33421 ccagatcttc ccattcacga gcgatttttt cgccaagttt ggtgcccata ttcacacgag
    33481 cgctgtagac ggagattttg tcgataaagg agtccgggcg agcaaaataa acgtactcga
    33541 acagacaggg gttactgacc ggattatccg cgcactggcg cgtgaacagt tgcccctttt
    33601 cggtaatata gatagcttcg cctggcgcaa catcgcgcag gaattcaaag cccagcgtat
    33661 ccagcgccac gctttcagaa gcgaccatat actccgtacg accatcgcca acgtcacgct
    33721 tgcccagcac taacgggcga atgccgtgcg gatcgcgaaa agccaccatg ccgtggccga
    33781 taatcatcgc tacgcaggca taggcgccgc ggatttgacg gttagtcgcg gcaatcgcgg
    33841 caaaaatatt gtcggcttcc agcggatagt gacggaagct gtcgagctcg ctggcgaaaa
    33901 tattgagcag gatttcggaa tcggaggtgg tgttgatatg acggcgcttt tcttcaaaca
    33961 gctttttacg tagctcgtgc gcattagtca ggttgccatt atgggccaac gtgatgccat
    34021 acggcgagtt aacgtaaaaa ggttgcgctt ccgaagcgct ggagctgcct gcggtagggt
    34081 agcgcacatg gccgatcccc atgttgccct gcaaacgctg catgtggcga gcttcaaaaa
    34141 tatcgttcac cagcccgttt gccttacgca agcggaagca gttattcgca tcaatggtga
    34201 tgataccggc agcatcctga ccacgatgct ggagcactgt taacgcgtca taaatcgact
    34261 ggttgaccgg cataacaccg gagataccga caataccgca catacgtcat tttcctcgtt
    34321 aagccacatc tcagaacctg ttacgtcctg ggcaagaaac tcgacgagct ttgcagatag
    34381 tcaaagaacc atctgatgat gaagctgaac tgcgggatga gctgcgattt gctccagtct
    34441 tcgcttttcg acaagccggt aaaggtatca aggaagaaca gaatggcggc gacaatcagc
    34501 gcgcctcgca gtgcgccgaa acagatcccc aacacccggt cagttcccga caggccggtc
    34561 ttttctacta gctgacctat cacaaaattc acgatagcgc cgacgataag cgtcgcgata
    34621 aacagtaccg cgatagcaat cccattacga accagttcgt cttcaaagcc cgtaaaccag
    34681 acagacaggt aagtgtagta gtgactggcg acaaagaaag cacaacccca cgtcaccagc
    34741 gataacgctt cacgaacaaa gccgcggatc aggctaacca gacaggaaaa agcaatcacc
    34801 gcgataatgg cgtaatcaat ccagaccata gatgtcccac gattttacgc cctgtcgtcc
    34861 tgttcggggc gcattctaac agaaaaagaa aacgtttgcg tagggatttc cttcccacgc
    34921 gtaaataaaa atggcgctga aaaaatattc aacgccatca cactttttat ctcttcgggc
    34981 acgaccagaa gagctgccat cggcctgata agcgcaggat acccggttta ttccttctgc
    35041 cggatggcgg cgtaaacgcc ttatccagcc tacagaactt cggctattac cagatgaaca
    35101 ccgtaggcct taacgctgcg cgctcaggca aaacgcgcct tagttcgggc tatatcccat
    35161 caccacgccg cttaacccgg aaatctgctt gagctcgcca agcgatcctt tcatcttatc
    35221 tttcgacgca tccggcccga cgagaatacg ggttatttta ccctgtaccg gcgttgaggg
    35281 ggaagtataa acccggaacc cggcggaacg aagcttgccg actatctcgt tgactttatc
    35341 cgcgtttttc agcgcgccca actgtacgac ataggctttg ccggtcggcg caggtttatc
    35401 gtcggtagcc ggttgcggcg cgggcgtcgg cgtggaaacg gcgacaaccg gctgttgcgg
    35461 tttaggctgc ggcttcggct tttcaaccgg cttcggttta ggcgtctcca ccggtatcgg
    35521 atcaagctcg acattgttag acgccatgcg cgacgggtcc agcgacggcg ctgccgcatc
    35581 tcccgcccgc acctcttcag ccgccccttc cggcggctgt gtcggcagcg cctgcgttgc
    35641 ggcaggcatc atatccggct catcacggtc gccaggcttc ggtaccagtg gaatcgcagc
    35701 aaattcatcc tgataatgct ttttctgtcc gtccagcaga ccgggaagca caataacccc
    35761 cagcgcgact aacacaatcg tgccgactaa acgattctga aacttactcg ccaccgattc
    35821 tccccgcgtc tatcacttcc ataacatgtg cgacggtgtg gaacgatccg cacaccagca
    35881 cggtatcttc tggctgcgcc gcgtcgatag cggcctgcca tgcctgcgcg acgctatcat
    35941 agacattccc tttccccaga tgttccagaa gttgttccgc cgtcgcgccg cgcggcccct
    36001 ctaacggagc acaataccag tcgtcaacca cgcttttcaa ccaggctaac gtgccggcga
    36061 tatctttatc atgcagcata ccaatcaccg caagcacgcg cccgcgtttc ggcaacattt
    36121 tcagacgacc cgtcaggtat tccgccgcgt ggggattatg ggcgacatca aagataacgc
    36181 gcggcgactc actcacgatt tgaaaacgtc ccggcaaggt agcctgcgca ataccgtcgc
    36241 gaatcgcctg ttcgtcaatg ttcaacccgc tggcgcgcag cgcggccaga gcggtggcgg
    36301 cattcggctg gggaacctgc ggcaacggca gtccggcaag cgtgccgtcg ccatcggtaa
    36361 acgcccagtg ggtcgctgtc acctcataac gccagtcaac gccgcgacgc agcaacagcg
    36421 cgccggtctc ctgcgcgaca tccgcgatgg ttgccggcat ttccggttcg ccgacgatag
    36481 cgggtttttc cgcacgaaaa atcccggcct tctcgcggcc aatactttcg cgatccggcc
    36541 ccagccagtc agtatggtca agcgcgatgc tggtaattac cgctacatcg gcatccacaa
    36601 tgttcgtggc gtccaggcgc ccgcccaacc cgacctccag aatcaccacg tcaaggttag
    36661 cctgtttaaa cagccacaat gccgacaacg taccatattc aaaataggtc aatgaaatat
    36721 cgccgcgcgc cgcttctatt tccgcaaagg acgcggtatg cgcggattcc gctaattctt
    36781 tcccctgcac gcgcacgcgc tcggtgtaac gtaccagatg aggtgaacta tagacgccca
    36841 cacggtatcc cgccgcgatt aacaccgact ccagcgttcg acaggtcgta cctttaccgt
    36901 tggttcccgc aacggtaaaa acgaacggcg caggcttgag gatgtccaga cgcgctgcca
    36961 cctggcttac gcgctcaagg cctaaatcga tactcttgct gtgcaggttt tccagataag
    37021 aaagccacga ggccaggggc gacgcagctt gaggtataga tttgtttttc attgattccg
    37081 ctgcttcttt acggtgaaaa gcaaaagggc agagcctgcg gccctgccct tttcagttat
    37141 caggcctcag actcctgatc cggcgccgga ggcaccacca cgccttcacg cggggcgtcc
    37201 gggttcggcg cgggcagatt catcagcttc gccagaatgc tcgccagctt caggcgcatt
    37261 tccggacggc ggactatcat atcaatagcg cctttttcga tcaggaactc actgcgctgg
    37321 aatcctggcg ggagcttctc acgaacggtt tgttcgataa cgcgcgggcc ggcgaagcca
    37381 atcagggctt ttggctcggc gatgttgaga tcgcccagca tcgcaaaact ggcggaaacg
    37441 ccgcccattg tcggatcggt caataccgag atgtagggca gaccacgttc ctgcatttta
    37501 gccagcgccg ccgaggtttt cgccatctgc atcagcgaca tcagcgcttc ttgcatacgc
    37561 gcgccgccgg aagcagagaa acacactaac ggacagttgt cttccagcgc ctgttcaacg
    37621 gcgcgaacga agcgtgcgcc aacgacagac cccattgagc cgcccatgaa cgcgaattca
    37681 aacgcggcgg cgacaaccgg cataccgtga agcgtccctt tcatgaccac cagcgcgtct
    37741 ttctcgccgg tttctttctg cgcggacgcc agtctgtctt tatatttttt ggagtcgcga
    37801 aacttgagca cgtctttcgg ctccagctcg ctacccaact ccacaaggga accttcatct
    37861 aacaggctat gcaggcgatt gcgcgccgac atgcgcatat gatggtcaca cttaggacag
    37921 acctcaagat tacgttccag ctcagcgcgg tataaaacct gaccgcagct atcacacttg
    37981 gtccacaccc cttcaggaat gcttgccttg cgggtgggag taatgttgct tttaattcgt
    38041 tcaatccagc tcattggtga cctttctgcc tgaaccttag tcagctttat tataaggggc
    38101 gcataatgcc atttttgccc ccaacagacc atgaatgttg cacattaaaa cataacagcc
    38161 cgaaactttg gataaaaaag tggtcgaacc gctgagttac tttctatttt gcggcacgcg
    38221 acgcagcgcg cttatgccgg acaatctcaa tgacgccagg taatatcgaa accacgataa
    38281 tccccacaat cagcagctta aggttatcct gaatcaacgg tatcgtaccg aagaaataac
    38341 cggcgtaggt aaagagcagc acccacagca gcgcgccgat gacgttatag gcggcaaaat
    38401 gccgatagga catgtgcccc atccctgcca caaacggcgc aaaggttctg acgatcggca
    38461 cgaagcgagc gagaatgata gttttaccgc cgtgtttttc ataaaactgg tgggttttat
    38521 ccagataact gcggcggaaa attttcgaat tcggattact gaacagtttt tcgccgaaca
    38581 gtcgaccaat cgtgtaattt accgcatcgc cgacaattgc ggcgatcagc attaacgcca
    38641 ccatgacatg cacattgaga tcgttggttt ccagcgaagc cagcgccccg gcgacaaaca
    38701 gcagcgagtc gcccggcagg aacggcgtga cgaccaggcc ggtttcacaa aacagaatca
    38761 aaaacaaaat agcgtacacc cagacgccgt actccgcgac cagctccgcc agatgcacat
    38821 cgatgtgcag aataaaatca ataataaagt agatcaggtc catatttgtc tttgcctttc
    38881 tacccgacac gtttcgggtg tgcgattcgg attagtccgc cagaaatagc gggcccattg
    38941 gcggttttgg aaggtcaaac cggtcagggt aatccaccgc aaccaaatat agcccttccg
    39001 ccttcgccgt tgccgccgcc agcgttctgt ccctggccgc taacagctct gcgatccagc
    39061 tctccggctg gttgtgagcg cctacttcca gcaggctgcc gacaatattc ctgaccatat
    39121 gatgaacaaa ggcattcgct ttgatatcga ccaccacata agggccgtgg cgggtaacgt
    39181 tgatgtgcat cacattacgc cacggcgtgc gcgactggca ctgcaccgcg cgaaacgagg
    39241 taaaatcatt ttcgccaagc agacactgcg ccgcgcgatg catccgctct gcatccagcg
    39301 gctcatagta atgcgtcacg ccttttgcta ataccgcagg acgcagtcga tgattgtaga
    39361 tgatatagcg ataacggcga gccgtagcgc taaatcgcgc gtgaaaatca tccggtacag
    39421 ttttcaccca gcgcacggca atgtcaccag gcaaattcgc atttaccccc agcgtccatg
    39481 ccgcatcttt gcgcaatgcg gtcgtttcga aatggacaac ctgcccggtg ccgtgaacgc
    39541 cggcatcggt gcgcccggcg cagaacacgt taataggttc atttgccacc tgcgagagcg
    39601 ctttttccag cttttcctgc acgctgcgca cttcattctg acgctgccag ccataatact
    39661 tgctgccgtc gtactcaata cccagcgcaa ttttatagac cggcgatgat tgctgtccgg
    39721 acatcagtac agatactcct gcaccagctt ctccgcaatt ttaacggcca tcagcgcgcc
    39781 gccgaaacgc acgttgtccg ccactgacca gaactgaatt tgttccggca taccgtaatc
    39841 attatgcaca cagccaatag agagctgtgg attgccggaa gcgtcgccca cctgcgtcgg
    39901 gtaatccgtc tcttctgaca gtacgatatc ttcaccgcgg gaaaacgcct cgcgcgcctc
    39961 ttccgccgcc agcggacgga gcgcttcaaa gctcaccatc tgcgcatggc catagaacac
    40021 cggcgactgc acgacactgg cggagatcat cacgccatca tcctgcaaaa ttttacgcac
    40081 ttcatcgacg atacgacgtt cctggcgcac gctgccttcc cgatccggca gcagcggcag
    40141 catattgaac gccaactggc ggccaaagaa atcatcttca tcaatcggta tgccgttaag
    40201 cagcttcgca ctttgtccgg ccagcgcatc gaccgctttt ttcccctgcg cggacgctga
    40261 taacatactg gtgacggcga tgcgcgacag tcccccctga tcgattaacg gcttgagcgc
    40321 cgccagcagt tgactggtca gactatcggc gaccgcaatc acgttacggt tacggtaatc
    40381 cgccagtaca tacgggttaa cttccggcac gaccagcggc acatcaggct ccagcgcgaa
    40441 cagaccgctg gaatctatca ccaggcaacc tgcattggtc gcgtcgtcta tccaggcagc
    40501 cgatgcctct gcgccggcaa cgaaaaacgc caactgcgcc tgcgtccagt caaagtccgc
    40561 cgcatcctgg acaatgaccg acttgccacc aaaacggagg tgctcgcccg cgctttcatg
    40621 acgcgccaac gcataaattt caccgaccgg gaactggcgt tcagccagtg tttcaagcag
    40681 ggcttcgcct acggcgcccg ttgcgcccag aatggcaatg ttccagcctt cagacatggt
    40741 gatttactcc agaaatacat aagcgtccct gtcgcattat tcgacaggga gcattaagaa
    40801 gacattaatg tgccgggtga tgaacagcgt taaaacctag cttacacagc aaggcggctg
    40861 ccgtttcgtc gtcacacatc acgtataaag acgaccattc acggcgctca agataatttt
    40921 tacgcaattt atcaaattca cccggaattc cagcgacttt acgcagtggc gcatcgtcgc
    40981 ggcgcacatc atacaccaaa tgcgccagtc ttttcagcgt cggttgatcc agcgggccgt
    41041 gaagcgtaat acgaccaaac tcaggcgcag gcagtaatgt ctccagcgcg acacgctgct
    41101 cgcgaccgat aaacgcgcta tacgcctcaa agacctgggt ggtgccgcgc gctttgcctt
    41161 ccagcgtata gccggcaata tgcgacgtgc cgatatccac ggcttccagt agcgcgacgt
    41221 taagatccgg ttcgccctcc cacacatcaa gcaccacgct cagcggctgc ccggcattga
    41281 gtcgcgccag caatgcggcg ttatccacca ccgggccgcg gcaggcgtta atgagaatgg
    41341 cgccgggttt cagtcgacgg atcagcgtct catcggccag atgcagcgtt ttgtacggtc
    41401 cgtctttata gagcggcgta tggaaagtca ggacatccgc ttcctgcacc agctcatcca
    41461 gcgtacgaaa atcaccctcg tccccgcgtg cggcgcgtgg cggatcgcac agcaacgtgc
    41521 ggatacccaa cgcttcaagc ctggtctgta gccggcttcc gacgttaccc acgccgacaa
    41581 tccctatagt gcgatcgcgt aacgaaaagc cgtcacgttc ggccagcatc aacagcgcgg
    41641 aaaacacata ctccaccacg gcgatagcat tacagccggg cgcggctgaa aaaccgatgc
    41701 ccgcctgctt cagccatgcc tcatccacat gatcggtgcc tgccgtagca gtaccaacga
    41761 agttaatcgg cgtgccgctc agcagcgatt cattcacttt cgtgaccgaa cgcaccatta
    41821 acgcatcggc atggttcaat tcttcaacgg ggatcgggcg acccggcact gcctttacct
    41881 cacccaggcg gctaaataat tcgcgggcgt aaggcatatt ttcatcaacg agaattttca
    41941 cgactgtcgt acctgtttga gaacgagagt taaccggaca agtgtgccat aatctggccg
    42001 ccaagcatat attgctcaga tttatggtta aaggataatt aattatgcat cccatctccg
    42061 gcgcccctgc acagcctcca ggcgaagggc gtaatcctct ttccgctgcg agcgagcagc
    42121 cgctttccat gcaacagcgt acggtactgg aaaggctgat cacgcgcctg atttcactga
    42181 cccagcagca aagcgcggaa gtatgggccg gaatgaaaca cgatctgggg ataaaaaatg
    42241 acgcgccgct actgtcgcgc cacttccccg ccgctgaaca gaatcttacc cagcgtctgg
    42301 gcgtagcgca gcaaaatcac gccaatcgtc aggtgctttc acagctaaca gagctgcttg
    42361 gcgtcgggaa taatcgtcag gccgtcagcg attttatccg tcaacaatac ggtcaaaccg
    42421 cgcttagcca gcttacgccc gatcaactca aaaacgtgct gacgctcctg caacaggggc
    42481 agctttccat tccgcagccg caacaacgtc cggcaacgga tcggccatta ttgcctgctg
    42541 aacataatac gttgaatcag ttggtgacga agctggcggc cgcgaccggc gagtcaaaca
    42601 aacttatctg gcaatcaatg ctggaactct ccggcgtgaa aagcggcgag ctcattccgg
    42661 caaaacagtt tacccatctg gcgacatggc tacaggcgcg gcagacgctg tcactacaac
    42721 acgcgcctac gctacatacg ctgcaagctg cgttaaaaca accgctggaa ccggacgaac
    42781 tcacagcgat caaagagtat gcccaacaca cttatcaaat tcagccgcaa acggtgctga
    42841 ccaccgcgca ggtgcaggat ttacttaacc atattttcct gcgtcgcgta gagcgggagg
    42901 cggatgagct cgaaccgctc tctattcaac ccatctaccg cccgtttgcg ccgatgattg
    42961 aaaccgtgaa aaatctgtct gcgcgaccag gcctgttgtt tatcgcgcta ataattgtac
    43021 tggcgctttt ctggctggtt tcttaaccgc gccggaacga taatatcgtc accaggatgc
    43081 caaccaccgc ggagatcgct cccgcgagga atacggaagg atagccgtat gacgtggcca
    43141 gcatgcccgc cagcgggccg gtaacgccgt aggagatatc ctgaaacgcg gcgtagccgc
    43201 cgagcgccgt accgcgtacc tgtgcaggta cgcgtttcac aacctccacg cccagcgccg
    43261 agaaaatcag tgaacaccct gccccggtga gcgccgcgcc taccagcgct atccaggccg
    43321 tcggcgccag ccacaagagc agcaaccctg ccgtctcaac cagcaatgag acaacggcga
    43381 ccttcacgcc gccaaagcga tccggcatcc aaccgaacaa tatgcgcatc agtacaaacg
    43441 caccgccaaa cgcggtcagg gtgaatcccg ccatcgtcca gccattgctg acaaaataaa
    43501 gtgaaataaa cgtaccgatg acggcaaagc ccacgccctg caatgccagg cccaggcccg
    43561 gtttccagat aagcccgacc acgctccaca gtgaaggtcg ctcccccgta tacgcaggca
    43621 ctttacgcac ggtgccgttg aatgcccagg ccagcagcgg taaaaccatc gtcgtccccg
    43681 ccagcgccgc gaagccaaag tggctatgga tcagcaagcc caacggcgca ccggccgcca
    43741 gcgcgccgta aatcgccatc ccgttccacg acatcacctt accggaacgc gttgggccaa
    43801 ccagccccag tccccaggtc agggttccgg tcagcagctg gctttcgcca aatccgagga
    43861 tcaaacgccc aacaataagc agcgcgaatt ttaccggcgc ggaaaccggc aacagcgcgg
    43921 ccaggagcca ggcggcgccc gccagcccgc aggcaagcat cccctgtaac gccgatcgtt
    43981 tagcgccata ttgatccgcc agccgtccgg catagccgcg cgtcagtacc gtcgcaaaaa
    44041 actgaatgcc cacggcgatc ccaaccatcg tattgctata gcccagttcg tgatggacaa
    44101 aaagcggaat gaccggtaac ggcaggccga ccgtcatata ggtcaggaaa accgcaaagg
    44161 cgatgcggaa cagcgaaaaa tccgcagacg gggtcgttgt tttttggcta actgctgtca
    44221 tgcattactc cagaatgcag agtaaggcgg ggaaaggcca cgcccccctc tacctgaacg
    44281 tcaggattaa ggtgcgttgg ataacgttaa acgcttacgc attatcggaa ggataatgta
    44341 gaaagtgaag tctgcctgtg agacgcgaaa cttgtcaacc ttgaaattgc agccagggta
    44401 tcaacgcggc ggcgtgtcat caaacagaaa gagaaagacc gctttcatcc ctctcacctt
    44461 aaaccgtcca gtcacctgct tgcgctgttc tggcgtcagt aacctgaaca tcatctccca
    44521 gatatcttca ggctccgctt cctgtaagga aatgggttct ggcgtcggtt cctctccgct
    44581 gtcgtccaga taacgatgaa catagagagg gaaaacagat atatgaaact cctcggcctt
    44641 tgatttaaca cgcttacgcc tgacccccgc tttcccttca ctgtacttat ataaacgttc
    44701 gcgaaccgca ggctcgcttc ccggaaaccc cggtaagcca agacattcct taaccgtgaa
    44761 ccattccttt gccatcggtt tctttccttt cccctgatga aataaaaata tttcttcttt
    44821 ttcgcgaaat tttgctttct ttctggcact attcttagcg tgaaaaagaa agtaacttcc
    44881 ttttccatgc gctaatttta tcttaaaaat atcggcgccg ataacacatc ttcttaggat
    44941 tacagaatgg aaccaaaaag ccaagactgg catcgtgcag atattaaaag tgcactggaa
    45001 aaaagaggta ttacgctcag agatctttct cgtcaggccg gtttatcacc tgattcactg
    45061 cgcaatgtct ttacccgttc ctggccgaga gccgaacgga ttattgcgga cgcgctgggc
    45121 atcacgccgc aggagatctg gccgtcgcgc tatggcgata tgcaaataaa aaat
//
LOCUS       DAJVKX010000023        44979 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000023 DAJVKX010000000
VERSION     DAJVKX010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 44979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44979
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.023"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(128..646)
                     /locus_tag="OPY25_001241"
     CDS             complement(128..646)
                     /locus_tag="OPY25_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCS0926893.1"
                     /translation="MELKNVTRYIPDDPDYDNSFLYFRSEDGQDFYESLSKFTKKYKL
                     CIDSENIIRSVSEDVSRLYPAGFSVVEVNKLPAGFNIYGDWKYSNGTVLAVPVDYQAK
                     AETTRQKLLDAANSTIADWRTELALGEIGDDDKDSLTKWMAYIRALKTLDLSGVKDSA
                     TFTEIRWPELPQ"
     gene            complement(661..2172)
                     /locus_tag="OPY25_001242"
     CDS             complement(661..2172)
                     /locus_tag="OPY25_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0926894.1"
                     /translation="MAKNDFKPFATGKGANVTSQPDWEALPALLSGFTAGKASSAQVN
                     KALRQASFIAAALAQYTASKSGKDVLDDGDLSGFIAKMSAAFGKDFQTLDATLTALAG
                     LATGADKLPYFTGNDTAGQTDLTSVGRDIIGKASIADILTYLGLGETINLAKNAVPAT
                     RRVNSKPLTGDITLWASDVGAISADAVGEITDNGTMASANAPGWWKVAVSNSDTVVDF
                     PTYPGGSKLYSYGYLFVEKIGDVWFQHYYAHIGANAKRQDWGTVPNTSRPWVIDYNTA
                     NKPSASDVGALPITGGRLNGPLSIGTDNALGGNSIVLGDNDTGFKQNGDGILDTFANS
                     QHTVRVAPGEMQVLGAIRAGDAKRMTMTSSNNSVLNAQFHLWGDGNRPTVIELDDDQG
                     WHLYSQRNTDGSIQFVVNGQVIPDNYGNFDARYLTSGNVYTKGESDNRYVQNIQRGAP
                     VWPGKVDEYGPAEAPAGCFLTQARHDPTTAYGVTFAYRPLQMWVGNGWRTING"
     gene            complement(2172..2852)
                     /locus_tag="OPY25_001243"
     CDS             complement(2172..2852)
                     /locus_tag="OPY25_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2612 domain-containing protein"
                     /protein_id="HCS0926895.1"
                     /translation="MSKYTDLITNYHATKPKFVEHIDLVTRPLAETSAAINGLISAFD
                     IDYATGIQLDILGQWIGLSRVVSQPISGVYFSWDTDGLGYDQGVWQGPYDPDSGYTSL
                     SDETYRIVLKTKIAINNWDGRNDSLPPILDAALDGSGLKMQIVDNQDMTIGIWVFPET
                     DISSVSLELIAAIRQGYLTVKAAGVWGGSIEIPSVETPSEGNRFFGFDMDNEYISGFD
                     AGSWGTLL"
     gene            complement(2849..4048)
                     /locus_tag="OPY25_001244"
     CDS             complement(2849..4048)
                     /locus_tag="OPY25_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001197067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCS0926896.1"
                     /translation="MALNLDTLGLSATVTAEGISAPDYQTILDTLTSYFQQIYGSDAY
                     LEPDSKDGQMVALVALAIHDANNTAISVYNCFSPATGYGAALTSNVKINGIARKGATN
                     STVDLLLTGTAGTTITNGTVKDTNNVIWRLPDSVVIGVDGTVTATAICSKSGAVAAPA
                     GTITTINTPTRGWTSVTNPAAATVGAPAETDAELRIRQGQSVAIPSITPFEGVDGAIA
                     NIAGVTRHKLYENDTGKTDGNGLPPHSISAIVDGGDVTEIARTIRGNKGQGVRTWGKT
                     SVTVPDKYGNPHIISFSRPTDVPVYGKITLKVFAGYTSQIGVQIQQAVADYINRLMIG
                     DQVLLSRIYSPANLGVVSGGNARYYDIQELLIGKSPETVDAANINIAYDESASCKPEN
                     IIITVAA"
     gene            complement(4049..4402)
                     /locus_tag="OPY25_001245"
     CDS             complement(4049..4402)
                     /locus_tag="OPY25_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926897.1"
                     /translation="MRYRREDTEGDYTFGSGDDTWLINSPEAVAQAVKTRFALWYGQW
                     FLDKTEGTPWIQSVLGKQKPETYNLAIRKRILETRGVKSILSFNTTVNTTTRRVQFFA
                     EIDTIYGTTTVTSEA"
     gene            complement(4643..5398)
                     /locus_tag="OPY25_001246"
     CDS             complement(4643..5398)
                     /locus_tag="OPY25_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCS0926898.1"
                     /translation="MPVSLSSQLGSKEQADTRLVGSVMSALRVSMPGIVQSFDPDTVT
                     AVVQPAIKGYEPDSNGVSQSTTLPLLVDVPVVFPRGGGCTLTFPVKAGDECLVIFADR
                     CIDFWWQNGGVQEPVDDRVHDLSDAFCIVGPQSQAQKISGISTSAAQLRTDDGAAFVE
                     VAAGHNVTVKTPGALTATAEGGTTITSPIITLNGDVTINGNLSQGMGEGGGSATMLGP
                     VTVTNDVKAGGKSLMTHTHSGVQTGGGNTGAPN"
     gene            complement(5457..5885)
                     /locus_tag="OPY25_001247"
     CDS             complement(5457..5885)
                     /locus_tag="OPY25_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926899.1"
                     /translation="MPVMHNCFLELARESLQHNGEQWTRNAISRSYYGMYHSALRITN
                     NLTPTHDTDGERLPGGSHMRLYTAFCNGEAAKVNGVDVDKVRKIGIKLKMLHAQRVNA
                     DYRLERKINRITAISALQDAEEIDALVDRMMNNPDDSLTA"
     gene            complement(5885..6616)
                     /locus_tag="OPY25_001248"
     CDS             complement(5885..6616)
                     /locus_tag="OPY25_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000050472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926900.1"
                     /translation="MSLAQPKSGELLEILGPSLTQGENLLSEFEIHAVIRDARNVPEY
                     YQGLSIEGLAKLVLGEVEEGCALCEKSLAIAPDDSVSFCNYTIALRNKGYHVKQYEII
                     KRAINSRNPRILSEVAINAAYWVDLDLLKKVMPMLNAMEVAKADDLLKCNESLDYLID
                     HENHSHDLKAIGQLMMTIAEKYRLRLAGAHAFYVMNELNTFFVEIKTDDPALLSKVNN
                     DLANELIAAGLENSECVGCFQAGDF"
     gene            complement(6811..7146)
                     /locus_tag="OPY25_001249"
     CDS             complement(6811..7146)
                     /locus_tag="OPY25_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000826019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926901.1"
                     /translation="MKRLLLAALLVCISFTSFADTGCGPFTINWKAQDGLARINGQKP
                     ETQKITFLKQKGDYDNVNIQWMVPGNGRWLGMDFVARNGKPILNVEVIRKNMDEPREF
                     WTYDCRKVK"
     gene            complement(7143..8174)
                     /locus_tag="OPY25_001250"
     CDS             complement(7143..8174)
                     /locus_tag="OPY25_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926902.1"
                     /translation="MSKNWMRHFELLLVDDKGDGIKISELKVTFNIQKMPATIFNGFV
                     GNFKVYNLSPTTQNRIMQKEFSRIQVIAGYKGQPDATGNYPDENVGMIFNGDIRFTVT
                     GKDNATDSWIMLQCIDSWEGHLNASVKTTVAAGWKYSDLFSLGMKSFGPYGIESGAVP
                     DMPETVFPRGRVVYQSTARLMNHIAGQCNAYWWYENNQVNIVPEDNYIGVATVLNANT
                     GLIGRPQQTMGAGVNVRCLINPNIKLGGLIRLDQASVYRTSLSNDQIAQSPARLDESE
                     SDGNLYVNGLPGMSQPASINTDGDYIVGSIDYTGDTRGQAWYMDLLCLAKDGKELLNS
                     KGIDAAKYT"
     gene            complement(8177..8479)
                     /locus_tag="OPY25_001251"
     CDS             complement(8177..8479)
                     /locus_tag="OPY25_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926903.1"
                     /translation="MEAVEIPLVADNQTFATTINGTVYHLSVIWRGEYWVLDLADSNG
                     SAIISGMPMITGADLLAQYRYMNLGFSLVVLCDVAGQENPTQFDLGTFSHLYVFTE"
     gene            complement(8483..9133)
                     /locus_tag="OPY25_001252"
     CDS             complement(8483..9133)
                     /locus_tag="OPY25_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926904.1"
                     /translation="MDFLSVLLQQRTRSIGIIIPDVVITEKHTDALEITEHPVEQPTN
                     AGASGEGAGYISEHAFRRPSEVVMETGFSGGGSLLDFADTSAIGLSLGLSPKELYQEL
                     LNLQRDRIPFDVTTGKRIYNNMLIKTLEVTTDKSSENVLLATLTLREVIITSTQSIRV
                     ASKNNMTEGVGTSAVQNTGTKTTVPPNNSILKSLPQMAQKGVTTVDGYLSNLFLGR"
     gene            complement(9133..11085)
                     /locus_tag="OPY25_001253"
     CDS             complement(9133..11085)
                     /locus_tag="OPY25_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase catalytic"
                     /protein_id="HCS0926905.1"
                     /translation="MNAETIKDFLVSLGFGIDEAGYEKFESVLAGVTANAIKTGLAVE
                     GAALSVVAFTAKIASGLDNLYWASQRTGATVQGIQSIGYAVSQVGGSVDAARTSLESL
                     SRFVRNNPGAEGFLNRLGVQTRDASGNMRDMAAIFTGVGQELSSMPYYRANQYAQMLG
                     IDENTLMAMRRGLGGFSGQYSAMAKAIGFNADEAAKSSNRFMTSLREFGAMAGLARDK
                     IGSNLAGGLAGSLDTLRRHILDNFPRIEQTLTKAIKGILTLGDIIGRVAFRIVEGVGD
                     IIDWWGKLDKETKTLIEVIGGLVVAMRILNSTFWMSPVGLITGLIVAFGLLWEDYKTW
                     KEGGNSLIDWEKWQPAIDKAKDAMVWLRDHLLELKDSIGGWKTSLELLATFIAGAWIS
                     KVTGAFARLAGIPMPPWLKGWMAYAAYLYDDRENIVASAQSSIDYAKQNIGDGMRALG
                     IDTDFGRNPHTVKGANIQPDIPGAEPVQHAQSAKRTLADRNNNPGNIRPVGGNGFRFF
                     ESALQGWEAMKNQLMRYFTGKTTGRALQTIQDIVSTWAPAGDNNDPKKYAQDVAKWMG
                     VSPNTVLNLANPETMAALMQSMARKEGYSNWNSPLAYQAAGGSLNQQTVINVHGVNNP
                     QEAANLIADKQGAVNARAVQQLKGPA"
     gene            complement(11263..11715)
                     /locus_tag="OPY25_001254"
     CDS             complement(11263..11715)
                     /locus_tag="OPY25_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926906.1"
                     /translation="MECSVKGHDYRVAKLSVFDQLKVTRKLLPVLAGMMSDFGGIRSL
                     LPADGKIDSAKFDALKPVFETLLPRIAEELSSLTEEDTNAIIHPCLAVVSRKHMGGWA
                     PVFNSGQLMFDDIDLLTMLQLVARVVADSLGNFLQGLPTNGTPTPPAE"
     gene            complement(11719..12159)
                     /locus_tag="OPY25_001255"
     CDS             complement(11719..12159)
                     /locus_tag="OPY25_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3277 family protein"
                     /protein_id="HCS0926907.1"
                     /translation="MATYSFMDVTASISGPTGEIDLGYGSASSEEGITVAMGGPKNTM
                     TIGADGEVMHSLHADKSGTVTVNLLKTSPTNKKLSLAYNAQSQSSGTWGNNVIVIRNK
                     VSGDIITARSVAFQKQPDNANAKAGNTMPWVFDCGKIDQVLGEF"
     gene            complement(12171..13316)
                     /locus_tag="OPY25_001256"
     CDS             complement(12171..13316)
                     /locus_tag="OPY25_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3383 domain-containing protein"
                     /protein_id="HCS0926908.1"
                     /translation="MPQGLPVSNVVNVDVIIGPRAATGRNFGSLLILGTSTVIPVKER
                     LRLYSSKEDIGSDFGVDSPEYEAATVYFSQSPRPKEVYVGRWAKTLATGEAGAAEKLM
                     DAVNAVMGYTNWYGLGIADKEDIADDDWLKVAAAVEASGVSRILAITTSDPATFDATS
                     TGDLSYKLKAAKYGRTFVQYSSSSKYAALSAFGRAFTVNFNGSNTTITLKFKQEPGIT
                     YETLTTDQAAALDAKNCNVFVYYQNDTAILQQGVMSSGDFFDERHGLDWLQNYVQTNL
                     YNLLYTSTTKVPQTDAGVTRLLSNVEQSMDQSVTNGLVAAGVWNGGPIGQLDSGDALT
                     KGYYVYAQPISEQAQADREARKAPVIQVSCKLAGAVHFADVQINVVR"
     gene            complement(13320..13883)
                     /locus_tag="OPY25_001257"
     CDS             complement(13320..13883)
                     /locus_tag="OPY25_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926909.1"
                     /translation="MEDFPLSNNSSTEPGWLTPVSGDPDYDEALDRLLSQWVRNVSGL
                     PTGMVRPRWQKDQPPLLPAETNWCAFGVTGWPIDNSPAFTNQTEEGAQLWRHETFECM
                     ASFYGPAGMTFASRFRDGISVAQNNAELNALGLSMGDYTGLTPFPELINQQWVRRYDI
                     TVRLRRKVVREYGIKSLVDAPVSFFGD"
     gene            complement(13858..14247)
                     /locus_tag="OPY25_001258"
     CDS             complement(13858..14247)
                     /locus_tag="OPY25_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001687820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor"
                     /protein_id="HCS0926910.1"
                     /translation="MPTLDVTDVLFDPDFCDFNLWVTRRVQTVDEDGIGSDSEVKTQF
                     AGVVTVDRSLENRRMQSGQVISGAILIVTTERLTQGQTGRDADIVTYQNRDYRVTFVD
                     PYTAYGAGFVQAHCELLPFDGGFPVEQ"
     gene            complement(14234..14788)
                     /locus_tag="OPY25_001259"
     CDS             complement(14234..14788)
                     /locus_tag="OPY25_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926911.1"
                     /translation="MSFKSGVTTRVDNAQAILDALKSLTKKDVLVGIPAEDSDRDDVS
                     FGNAGIGYINEYGSPAQNIPPRPHLVPGVKSVEDQTMPQLKAAAQAALDGNAAGAERA
                     LNRAGTVAARGVKNHIKAANFTPLADSTVEARARRGRKGAKAELARRAAGESPGTTLA
                     KPLYDTGKYLASITHVVRDKDADS"
     gene            complement(14785..15192)
                     /locus_tag="OPY25_001260"
     CDS             complement(14785..15192)
                     /locus_tag="OPY25_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4054 domain-containing protein"
                     /protein_id="HCS0926912.1"
                     /translation="MPKNQSLPTVSDFRRDFPQFADPARYPEAQIEFRLNLADELLSE
                     NVTGKKLFPYFAELFVAHYMTLWAADSRAMLVGGPGGSTNGVQSSKSVDKVSVSYDTS
                     ATLNPDAGFWNNTRYGAEFYQLITMFGAGGRQL"
     gene            complement(15158..15526)
                     /locus_tag="OPY25_001261"
     CDS             complement(15158..15526)
                     /locus_tag="OPY25_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926913.1"
                     /translation="MAKEKLVTIHVHTPFTLTLGDQSKQEFGRGRHNVPEEVASHWFT
                     RAHAELSESGSNETDDQQPVIDSLQAQIADKDKLIADLKDALLKLQEQNDSLQAQITS
                     ARTGGNGAKDAKESKPANSK"
     gene            complement(15568..16509)
                     /locus_tag="OPY25_001262"
     CDS             complement(15568..16509)
                     /locus_tag="OPY25_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2184 domain-containing protein"
                     /protein_id="HCS0926914.1"
                     /translation="MITFDQATVDSSGAFLIGELERLDQGLNLPLVGYTWTRDIQLRE
                     DVSIADDISSWTNTSFGVAGSGANPNGKNWVGKDSTAIAGVNVDISKDGNPLNLWGME
                     LGWTVVELAAAQQVGRPIDTQKYDGMQLKWQMDNDEQVYVGDEALGLKGLTNLVGVTL
                     NNATKTWANSTNDEILDSVNSILSNAWAASGYSVVPSDLRIPPEQYSLLASRKVSEAG
                     NQSLLTYLAVNTIAFHQNGVPLEIKAVKWLKGRGVGGKDRMVAYTNDKKYVRYPLVPL
                     QSVPVQYRGLYQIATYYGKLGAVEPVYKETLSYVDGI"
     gene            complement(16521..17018)
                     /locus_tag="OPY25_001263"
     CDS             complement(16521..17018)
                     /locus_tag="OPY25_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926915.1"
                     /translation="MTAYLYRMPVGIAGAISRPQDLTVEPVILKSDNAFAAYGLAGKY
                     DADGFFVPLAEGDTVDKVKGIYVRPYPTTSQPDMVRQVGTDKNFPGDAMKRGYMTVNV
                     GTDASSVKKGGVVYIVVSADASIPVPLGGITAAEVTGKTAALPDAFFTGAGDANGNAE
                     ISWKI"
     gene            complement(17023..18255)
                     /locus_tag="OPY25_001264"
     CDS             complement(17023..18255)
                     /locus_tag="OPY25_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2213 domain-containing protein"
                     /protein_id="HCS0926916.1"
                     /translation="MKYFFNTRLGETRYQLADGSLLCRDVPIGRTGKQLYGAADLPNL
                     KPDKFGEIVVTRSPEQVFHPATLASFEGMSITILHPEDENGNVRLVNPENWKELAVGH
                     LQNVRRGTGEQSDLMLADLIVKDESAIQLIEDGLREVSCGYDAEYEQAEPGKAEQVDI
                     TGNHVALVPKGRAGNRCAIGDRDTMANQKKSWWTRMRTAIKTGDSDTMNELLDSAPAA
                     VTGDEGDLPGGVNLNINLSPQQPLPDKKPEMGGDVTGDGEDDIKTLLKALLAKLEGTA
                     TGDNADTPDDKDKKDPTGDGEDNEEETTITGDSAYRAEVIIPGIDLSRKVKPTAFKRD
                     VLAAADKTLVRQVVGDADIRKLPKQSVDMAFNAVSEIAKGRNTRSTTGDAQRPGMGMT
                     SIASLNKQNADFWSNRKG"
     gene            complement(18270..19007)
                     /locus_tag="OPY25_001265"
     CDS             complement(18270..19007)
                     /locus_tag="OPY25_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HCS0926917.1"
                     /translation="MSTNRQSRQAEIRYRTSLRQIARAVGDIVNGHYDGSNDSVTEIM
                     EALERYSEIITPWATKVAENFTADIVRKNDEQWRKHSKTISRELRNLVSNAPPGQVMK
                     SIVAEQVKYIKSLPLEAADRVYDIQNRAIEAVVTGGRAEHFAKEIAASGDIAKSRADL
                     IARTELGRATGALDQARALSIGSNGYIWRTAEDGDVRHSHREMEGKFVEWGRPPTLDG
                     MTGHAGELPNCRCYKEIVFPNPHSYLA"
     gene            complement(18892..20361)
                     /locus_tag="OPY25_001266"
     CDS             complement(18892..20361)
                     /locus_tag="OPY25_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1073 domain-containing protein"
                     /protein_id="HCS0926918.1"
                     /translation="MARNKQASRRTVQATADGYENFVTRVGMQTPNQHSASTYRANFT
                     SRNRMLVEWSYRSSWLIGEAVDAIPDDMTRKGIRITSEIDAKDRGTLEAQLDQLQIWD
                     ALNDVLKWSRLYGGAVGFIMIEGQAPMTPLRLETIGEGKFKGILPLDRWMINPVLTRR
                     IKEMGPNLGKPELYDVVTTATGIPAWRIHHSRLIRFDGVTLPFQQKMTENEWGMSVVE
                     RIWDRLTAFDSATVGAAQLVYKAHLRTYKVEKLRELIALGGPAFEALLKNIDLIRQFQ
                     SNEGMTLMDAKDTFETHQYSFSGLDDILSQFAEQISGAVGIPLVRLFGQSPKGFSTGD
                     ADLANYYDRVSSLQERRLRLPVRRVLDIMHRSELGKPLPDDFTFEFNPLWQMSDVDRS
                     TVAVNTTTAIVNALDAGLMTTKAAMTDLRENSDVTGIGASITDEDIENAEDEAPPGIG
                     ELVDKPPEPTGGDPISNEPTADSAGGRGYRKWALRWFKR"
     gene            complement(20361..21764)
                     /locus_tag="OPY25_001267"
     CDS             complement(20361..21764)
                     /locus_tag="OPY25_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HCS0926919.1"
                     /translation="MTSTPISRPTLNPALRNFWTTQARNKVLYGGRSSSKSWDAAGFA
                     IFLANKYSLRFCCARQIQNKIEESVYTLLKIQIDRFGLRHRFRILNNKIINRVTGSEF
                     VFYGLWRNIEEIKSLEGIDVLWLEEAHALTEYQWKILEPTIRKEGSECWFIFNPGLVT
                     DFVWRNFVVDPPEDTLIRKINYDENPFLSDTMLKVIDAARRRDPEGFVHVYEGVPESD
                     DDAAIIKLSWIEAAVDAHKVLDFGPEGRKRIGFDVADSGADKCANVYRYGSVIYWADE
                     WKAKEDELLKSCQRTYQAAMERDADIVYDSIGVGASAGAKFSEINDDRKRENAYARRV
                     NYQRFNAGAGVHEPDDEYNGIPNKDFFANLKAQAWWLVADRFRNTFNAINNGEQYLVD
                     ELISIDSRCPLLEKLKLELTTPHRDFDRNGRVMVESKKDLAKRDIPSPNVADAFIMAF
                     APTDTSLDIWEQLGRQA"
     gene            complement(21730..22482)
                     /locus_tag="OPY25_001268"
     CDS             complement(21730..22482)
                     /locus_tag="OPY25_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926920.1"
                     /translation="MAKPDWEAIETAYRAGIMSLRDIGALYGVTEGAIRKKAKKLEWV
                     RKNITQVRKNGTQKNTVRTTRRPASSGAVQKHSRPESGPPADTKPEAVRKKVVTNHPP
                     FQPGNQYALKHGGYARRLLLKDEVVEDARALTLEDELFRLRANNLMAAENIGRWFTLL
                     EDAEEEQQRKILMDNISAAEKAMMRNTVRIESIVGTLATVSKIHADTDYRLAATDKVS
                     LEADRLRRDAGIDDGNGERDLNDFYADIQTDA"
     gene            complement(22572..22799)
                     /locus_tag="OPY25_001269"
     CDS             complement(22572..22799)
                     /locus_tag="OPY25_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926921.1"
                     /translation="MNQAIEQIIHSSLNKNEPGAGVGSSVTANDIIEGVRPYYQAASG
                     AEKLSIVERLNKLKVEPGVPIPSNIEQLLSN"
     gene            complement(22896..23273)
                     /locus_tag="OPY25_001270"
     CDS             complement(22896..23273)
                     /locus_tag="OPY25_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926922.1"
                     /translation="MFTVKTIINGVTHICEQPSISIARAGSETFADTLKLTHNSACPD
                     FAYWLPAIYEDPEMTKALQEEELVISDRTDVLDTDAIAIIIEEYPSENFPGAGDGCRY
                     QFIYPGDQVYVMNSHGSTIETVK"
     gene            complement(23316..23855)
                     /locus_tag="OPY25_001271"
     CDS             complement(23316..23855)
                     /locus_tag="OPY25_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 domain-containing protein"
                     /protein_id="HCS0926923.1"
                     /translation="MNLLSALLKRYWLQLAFILLMAGAFIAGNVWSDRGWQKKWADRD
                     SAESSQEVNAQTAARIIEQGRIIARDEAVKDAQAQAAKSAATAAGLSATVSQLRTEAK
                     KLATRLDAAKHTANLAAAVRSKTAGADATVLADMFGSLAEEAQYYAERSDESYRAGMT
                     CERIYNSVRESTNNPIAPH"
     gene            complement(23852..24466)
                     /locus_tag="OPY25_001272"
     CDS             complement(23852..24466)
                     /locus_tag="OPY25_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 19 protein"
                     /protein_id="HCS0926924.1"
                     /translation="MNQQQFQQAAGISAGLSARWYPYITAAMSEFGITAPLDQAMFIA
                     QAGHESAGFTVLKESFNYSVEALKKTFGKRLTPYQCEMLGRIDGRQVAHQPQIANLVY
                     GGRMGNKDAGDGWKYRGRGLIQITGLENYTRCGVALKLDLVANPGQLELERHAARSAA
                     WFFVTKGCLKYSGDLVRVTQIINGGQNGFGDRRERFEKAKSVLV"
     gene            complement(24466..24747)
                     /locus_tag="OPY25_001273"
     CDS             complement(24466..24747)
                     /locus_tag="OPY25_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCS0926925.1"
                     /translation="MVANDPSAVLNAVICGVIVIVLMFYRRGDATHRPLISLLAYVMV
                     LVYASVPFRFVFGLYESSHWLVVMVNILICAAVLWARGNVARLVDALRH"
     gene            complement(24734..25123)
                     /locus_tag="OPY25_001274"
     CDS             complement(24734..25123)
                     /locus_tag="OPY25_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001294874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCS0926926.1"
                     /translation="MSEPVSSATVLAGGLMGASVFGLATGTDYGVVFGAFAGSVFYVA
                     TATNIGRIRLVAYFITSFIVGVLGAGLIGTKLAAITHYEKPLDALGAVIISAMCIKFL
                     TFLNSQDLNTLFSILSRIRGGGSDGSK"
     gene            25340..25789
                     /locus_tag="OPY25_001275"
     CDS             25340..25789
                     /locus_tag="OPY25_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0926927.1"
                     /translation="MKNTALGKFIFIVGTALLLGGCSGMVMPPYATHGTSVGIIAPAG
                     GYSEWHTDSRNHTTGDSHSQSQGNCTQSEDSQLSENGLTRTHQSNCNTRSQTHSSSTS
                     KTRSSSVGFSVGGPVGASIGLIKQMESMNRAPANDMSSNEMFKNFGF"
     gene            complement(25925..26050)
                     /locus_tag="OPY25_001276"
     CDS             complement(25925..26050)
                     /locus_tag="OPY25_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926928.1"
                     /translation="MKMHNDPHSMDSQSIFAGSQLLPMEKTSHLALSVRFRSHLA"
     gene            complement(26449..27246)
                     /locus_tag="OPY25_001277"
     CDS             complement(26449..27246)
                     /locus_tag="OPY25_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HCS0926929.1"
                     /translation="MNLESLPKYFSPKSMMPGAVPCGITSDTLTITDVMASLGLLTAK
                     AAVGIELYLAKAGVLSSENIIAYIRQLAEQRAERHGALRKMEKGKRSKFLDTMARYVF
                     RDYSLSAASLVTCSSCHGAKLIDAEVFTNKVTYPDGKPPKWVKDTKGISPSDWEVWKS
                     VREQVRVVCKACDGKGQVKNECRCRGRGEILDKKKSELQGVPVYKKCPRCKGRGYPRL
                     KDTEIFKALGVTEMVWRYNYKLFFDRLVEHCHIEESYAEKVLGNVTR"
     gene            complement(27236..27382)
                     /locus_tag="OPY25_001278"
     CDS             complement(27236..27382)
                     /locus_tag="OPY25_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HCS0926930.1"
                     /translation="MKPELIEILRMRWLRLRIYRYRGSFPVAYRILRNYVRIEAKREH
                     RNES"
     gene            complement(27379..27990)
                     /locus_tag="OPY25_001279"
     CDS             complement(27379..27990)
                     /locus_tag="OPY25_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinG"
                     /protein_id="HCS0926931.1"
                     /translation="MAKLPRRKCANKECRQWFHPIREGQIVCSYQCASTVGKEQTRKA
                     REAAQRKAQSLQRAAEKKERAAWRQRKAAVKPLKHWIDLTQRAVNDICRETELAEGLG
                     CISCGTKTAFAWHAGHYRSTAAAGHLRFTRFNIHLQCDVCNVYKSGNIEAYRAALVER
                     YGEAAVLALENNNTPHRWTVEELKEIRLAALSDLRALKKLEAA"
     gene            complement(28199..28801)
                     /locus_tag="OPY25_001280"
     CDS             complement(28199..28801)
                     /locus_tag="OPY25_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1367 family protein"
                     /protein_id="HCS0926932.1"
                     /translation="MAHELQLIKQSSGILIPATPETSDILQSKIKLGAVLVAEFRQVR
                     NPAFHRRFFALLNLGFEYWEPTGGAISANERKLVNGYAKFLAAYGGNESALLDAAEQY
                     LEQIANRRVTNGISLCKSFDAYRAWVTVEAGHYDAIQLPDGTLRKHPRSIAFSSMDEV
                     EFQQLYKSALDVLWRWILSRTFRTQREAENAAAQLMSFAG"
     gene            complement(29136..29375)
                     /locus_tag="OPY25_001281"
     CDS             complement(29136..29375)
                     /locus_tag="OPY25_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001217670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI family protein"
                     /protein_id="HCS0926933.1"
                     /translation="MRIELVISRTKQLPEGAVPALEKELITRLQNQYENCNLTIRRGS
                     QDGLSIVGAADGDKKRIQSILQETWESADDWFYAY"
     gene            complement(29560..30057)
                     /locus_tag="OPY25_001282"
     CDS             complement(29560..30057)
                     /locus_tag="OPY25_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000963896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCS0926934.1"
                     /translation="MAIEYVEGVNYLSIEDIVYINRSLIEIQTPNEPIGVLNPNNLSS
                     SQSRPSTIRYYEQTDDMFRLSAVLIESLIQNHPFANANKRTAMMAGYVFLLLNGYELT
                     APSDEVVTIAEGLARKDYAVDDLENWLCHWSREYDSRTLCETGGNMIQALVATSRYIR
                     IKSNE"
     gene            complement(30068..30247)
                     /locus_tag="OPY25_001283"
     CDS             complement(30068..30247)
                     /locus_tag="OPY25_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016156674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926935.1"
                     /translation="MGHALKKADRLYIPPRDKSMVAKPRAAISKACSHTGQVKNAFEF
                     GFARYEKAMEELSKV"
     gene            complement(31093..31665)
                     /locus_tag="OPY25_001284"
     CDS             complement(31093..31665)
                     /locus_tag="OPY25_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF550 domain-containing protein"
                     /protein_id="HCS0926936.1"
                     /translation="MTTITKEWLQQTIAEFENTRDDIPFGLSDDDAKILIVLKRALAS
                     LEREQVRHEHADWSDATFGDVGPIGPLKHLSKEALETAAELGDLSEWADMQFLLWDAQ
                     RRAGITDEQIALAMVEKLAVNKKREWPEPKDGEPRLHIKEQPVPVVPEECPEEIRDLM
                     ASHSDALFNDDDAQEIWNACRAAMLNGGKS"
     gene            complement(31669..32142)
                     /locus_tag="OPY25_001285"
     CDS             complement(31669..32142)
                     /locus_tag="OPY25_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCS0926937.1"
                     /translation="MESQSILDMCCGSRMFWFNKRDERAVFADIRAEEHILCDGRRLV
                     ISPDLIADFRALPFADASFPVVVFDPPHLERVGQTAWMGKKYGRLNKKTWRSDLRAGF
                     KEAFRVLRAHGVLIFKWNETQIPVSQILALTDVKPIIGQRTGKNDKTHWIIFVKD"
     gene            complement(32142..32666)
                     /locus_tag="OPY25_001286"
     CDS             complement(32142..32666)
                     /locus_tag="OPY25_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
                     /protein_id="HCS0926938.1"
                     /translation="MSNIDKRALREVAERATPGNWRRTSSLFNGITVTPFSLCGEEVT
                     LAHTVEKRDAEFIAAANPATMLALLDELETKEEQRANWFRMAQKLGEDLDTAERLIAE
                     LDQRLIEYAGIATREARRVAELEARKVNLSKLSVGEVMHMTGFSRDYAEGWCAGNDNA
                     IHEIRTAGIKVKES"
     gene            complement(32663..33010)
                     /locus_tag="OPY25_001287"
     CDS             complement(32663..33010)
                     /locus_tag="OPY25_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HCS0926939.1"
                     /translation="MARPKTHSERMIILERIIGLVKEQGRITTNDVVAIFGVHRTTAE
                     KYLRIALERGGFIRHGRCGIFRDQRAVIDYDLRRYSSSQVTGFSALPVLEKSPVMQVY
                     GASKMSINKGGAQ"
     gene            complement(33021..33770)
                     /locus_tag="OPY25_001288"
     CDS             complement(33021..33770)
                     /locus_tag="OPY25_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCS0926940.1"
                     /translation="MKNVIGTGSALDRLKRIIPASVQPKFSTADEWRAWQEAEGRKRS
                     EELDRMNQKSRTEKIFGRSGIQDLHRSCTFANYEVSGEGQRKAYTMAKSYAQNFGSGF
                     ASFVFSGGPGTGKNHLAAAIGNHLLAGGHSVLVVTIPDLMLRVRECYDGGQSEASLLD
                     DLCKVDLLVLDEVGIQRGSSGEKVILNQVIDRRLSSMRPVGVLTNLNHEGLLDSLGAR
                     VIDRLQMDGGMWVNFDWESYRKNVSHLRIVK"
     gene            complement(33773..34756)
                     /locus_tag="OPY25_001289"
     CDS             complement(33773..34756)
                     /locus_tag="OPY25_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCS0926941.1"
                     /translation="MSMSNTAEIYKFPAPIPTQQECRMADLENGYLRLANQIQDALCI
                     VELSGREFRVLNAIIRLTYGWSKKSDRIANSLIADKTTLKVKHVSEAVLSLAYRNIII
                     LRRIGQTRYIGINTNLDKWAYSKPHCSKCPVSFPDDEIATWIISVPETRDSYTRKGGR
                     ASPKTGIVIPENRDSVLPHSAIPENGDSYPRKEGRASPKTGNTKDIIPKTNIKDLTPF
                     NPPKGKVKFDPLSIPVPEWLNAASWNEWVTYRQQSGKPIKTELTVTKAFRLLKECLDE
                     GHDPVNVINTSIANGYQGLFKPKFALNDRRAGRDVNHISAPDKTIPTGFRG"
     gene            complement(34841..35215)
                     /locus_tag="OPY25_001290"
     CDS             complement(34841..35215)
                     /locus_tag="OPY25_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926942.1"
                     /translation="MAYQAKRHQPNNHRGYLPMENAIARKLDPPEINPIEIESVLLNR
                     LASVGQKSYAEHMGISESTVSRRKAEGYFCNMAKELAFLGIQAAPPEAVLVSRNYLTA
                     VEILADAGLKAERARPDALGWD"
     gene            complement(35181..35417)
                     /locus_tag="OPY25_001291"
     CDS             complement(35181..35417)
                     /locus_tag="OPY25_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0926943.1"
                     /translation="MKVTVQRKILSVCSQAGLGRRLGRRAQTVNGWFKNKVPGELVVR
                     VARAIDWKVTPHELRPDLYPNPTDGLPSQEASAK"
     gene            35547..35951
                     /locus_tag="OPY25_001292"
     CDS             35547..35951
                     /locus_tag="OPY25_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001009036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0926944.1"
                     /translation="MNFGERLQRVLNETGITQSELGRRVGATSQSVNGWCQSGILPRK
                     DILELLPKATGKPLYWFFMEDDDESDVPERLTQGGPTDLNDRQKRLLEIFDQLPTVEQ
                     DRFIELAGTRLQELDDFMAEYQRRRKIEPPSR"
     gene            36240..36440
                     /locus_tag="OPY25_001293"
     CDS             36240..36440
                     /locus_tag="OPY25_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCS0926945.1"
                     /translation="MTNYGTTTLPRTSVVPGMLVKYQGRTYRASANVGKGLYLFTLFE
                     RLRTTNDEIEVYLNQHGKPATH"
     gene            36531..36827
                     /locus_tag="OPY25_001294"
     CDS             36531..36827
                     /locus_tag="OPY25_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor protein Gam"
                     /protein_id="HCS0926946.1"
                     /translation="MNAYLTYDRIEAQDWTRHYQQIAREEKESELADDLEKGLSLHML
                     ESLCMDELPRHGANKKAISRAFDDDVEFQERASEFVRYMAETFSRHQIDIESEE"
     gene            36833..37618
                     /gene="bet"
                     /locus_tag="OPY25_001295"
     CDS             36833..37618
                     /gene="bet"
                     /locus_tag="OPY25_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HCS0926947.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTRDGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTTYTTDRQPERDITPVSDETMREINDLLITLNKTWDD
                     DLLPLCSQIFRRDIGASSDLTQIEAVKALGFLKQKAAEQKVEA"
     gene            37615..38295
                     /locus_tag="OPY25_001296"
     CDS             37615..38295
                     /locus_tag="OPY25_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HCS0926948.1"
                     /translation="MTPEIILARTGIDVSNIEQGDDAWHRLRLGVITASEVHNVISRP
                     KSGKKWTDMKMSYFLTLLAEVCTGVAPEVNARALAWGKQYEDDARTLFEFTTDVKVTG
                     SPILFRDEDMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQF
                     SMWVTGIDAWYFANYDPRMKREGIHHVVVERDDKYMSLFNEMVPEFIEKMDEALKEIG
                     FTFGEQWR"
     gene            38373..39437
                     /locus_tag="OPY25_001297"
     CDS             38373..39437
                     /locus_tag="OPY25_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DGQHR domain-containing protein"
                     /protein_id="HCS0926949.1"
                     /translation="MSKIGDYFFEFPASRGLQGNTVVLMMTVPARALTRVLASDNHGN
                     TLERSQRELNPARAKKFYEYLRTAYEKKEPFIIPPLVGNCDSFIEFEEFGNTNVGVAR
                     FPMDAEIKLFDGQHRAAGIAEFCRTYGEPIHIPMMLTHQLPLKTRQQFFSDINNNVSK
                     PSAAINMAYNGRDKIAQDMVSFLSSHAMFSEITDFEHNVVPAKSDLWISFKPLSDATA
                     KFSGNGDELATSDIYDIWEAWLKLTAIKGIRHGCTPVEYKRDYIQFHAVMINAFGYAM
                     QELLRHRPAHIIVQMIEELVNNSTMSELENFFLISSWSGVCASTEKDRATVIASVASQ
                     KAASVRLIQAITTKSFEVAA"
     gene            39434..40315
                     /locus_tag="OPY25_001298"
     CDS             39434..40315
                     /locus_tag="OPY25_001298"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HCS0926950.1"
                     /translation="MRYGSVCSGTAAMPIEEPALRTWRRPFLKWAGGKYSLLPELDRL
                     IPAGKRLIEPFVGGGSVFLNSDKHERFLLADVNADLINLYQMLAVVPDSVIAEAMKAF
                     RHLNDAENYTVIREAFNAQKLNATERAAAFLYLNRHCFNGLMRYNLDGFFNVGWGKYK
                     APYFPEEEIRAFRQKSHACVFMTAGFERTLRLAGDGDVVYCDPPYEPMPGTAGFTNYA
                     SGGFSWDSQVALAESCVAAHQRGAKVFISNSTAPRVIELYERHGFTLHRVNARRSISS
                     KGSTRETANDIVASLGI"
     gene            40321..40560
                     /locus_tag="OPY25_001299"
     CDS             40321..40560
                     /locus_tag="OPY25_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4060 family protein"
                     /protein_id="HCS0926951.1"
                     /translation="MKLINRSKQSPVGRRACDIALAAHHEKFGDYGRQKHVTNYTVVV
                     DGVKVPVEVVNRATSYVATAMIGVRKLRNLPAQAN"
     gene            40601..40849
                     /locus_tag="OPY25_001300"
     CDS             40601..40849
                     /locus_tag="OPY25_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family protein"
                     /protein_id="HCS0926952.1"
                     /translation="MSNIIQLTPNKWVSEKVLIAVTGLKPGTITRARKESWMLGREYL
                     HISPDGNPKPSSECIYNREAVDQWIEAQKKNQPGAKTT"
     gene            40894..42186
                     /locus_tag="OPY25_001301"
     CDS             40894..42186
                     /locus_tag="OPY25_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3596 domain-containing protein"
                     /protein_id="HCS0926953.1"
                     /translation="MANASYPTGVENHGGSLRIWFLYKGKRVRENLGIPDTAKNRKIA
                     GELRSSVCFAIRMGNFNYVEKFPNSTNLARFGQDRKEITVLELTERWSELKRMEISSN
                     TMSRYESIIKNMLPLIGENKMVSAVTTEDLLYVRKELLTGFQVMKKDHRTQVKGRKSS
                     TVNNYMMLMAEIFQFGTDNGYAKENPFSGINRLKKAKGEPDPLTTDEFIKFIQACGHQ
                     QMRNLWSLAVYTGMRHGELCGLAWEDIDLHAGTIIVKRNLTQTDEFTLPKTDAGTDRV
                     IYLIQPAIDALRNQAQLTRLGRQFEVEVKLREYGQSVIQPCTFVFSPQCVKRGPRTGY
                     HYAVNSINKIWAPIIKRAGIRYRNAYQSRHTYACWSLSAGANPNFIATQMGHTDAQMV
                     YKVYGKWMSEKSAEQVSLLNQALSRYAPSLPQSMVAAQ"
     gene            42381..43583
                     /gene="pncB"
                     /locus_tag="OPY25_001302"
     CDS             42381..43583
                     /gene="pncB"
                     /locus_tag="OPY25_001302"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCS0926954.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGD
                     DLLGIYADAIREQVDAMQHLRLQEDEFQWLSGLPFFKPDYLNWLREFRYNPAQVCVTN
                     DNGKLNIRLTGSWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTAL
                     TANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQ
                     AHEWFQAHQQINPDLATSQRAALAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASR
                     YQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPKAVELYRHFASRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPQVRKAS"
     gene            complement(43664..>44979)
                     /locus_tag="OPY25_001303"
     CDS             complement(43664..>44979)
                     /locus_tag="OPY25_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HCS0926955.1"
                     /translation="KEIYRNTIGTLAGKNKQNTTGEAASKKSLKSIEVAATVLSGSLG
                     AGTIAGVAAAIAVGGPGAIFWMWIIAVVGMMTKMVEVTLAVKYRSKGENGEYYGGPMH
                     YIKKELNKKWYPLAGLYAFALMILVITDACFVQTNTMAAVIHYTFDIPTSVIGGFIVI
                     VGALVILKGLASLGKFCTIALPPITIAYFIGAAGVVVLNIEAIPQVIKSIFYYAFAPA
                     PAAGGFVGSTIMMAISKGASRGIFTNEAGMGTSATVHATANVDYAFRQGMWGAVEVFF
                     VSMITCNFTAFAVLASGMWTDASYQGIQIIFAALKETWHPIIVQVLCLGVALILFTSY
                     LGSYIKFRTSINYIFGDKLERIIKWLYFLPPLIAVNMEIPVIWLMADIAVGFLVIPNV
                     IALFLLRKEFISEFNLFRTRTQRDTNSEKTTQITHVNMSKSEGEE"
BASE COUNT        10866 a        12005 c        10802 g        11306 t
ORIGIN      
        1 gtttaaaagt aaataataag tacagtagtt ttttcttttc taaagaaaat ttacttatat
       61 cttagtgact tcgtacagat acctgaaccg aattaacacc taaaaactag caagtcagta
      121 gtagtcgtta ttgtggtaat tcaggccacc tgatttccgt gaaggtggct gagtctttca
      181 cgccgctcaa atccagcgtt ttaagcgccc tgatatacgc catccattta gtcaggctgt
      241 ccttatcgtc gtcaccgatt tcacccaacg ccagttcggt tcgccagtcg gcaatggtgc
      301 tgttagcggc atccagtagt ttctgtcggg tggtttcggc cttagcctga tagtcaacgg
      361 gaacagccag aacagtgccg ttcgaatatt tccagtcgcc atagatatta aatccggctg
      421 gtagtttatt gacctcaaca actgaaaagc cagccggata gagtcgcgac acatcttctg
      481 atacggaacg gattatattt tcagaatcaa tgcacaactt atattttttc gtgaatttac
      541 tcagcgactc ataaaaatcc tgaccatctt cactacgaaa atacagaaag ctgttatcat
      601 aatccgggtc atcaggaatg tatctggtta cgttttttaa ttccattata ttcacctaaa
      661 ttatccatta attgtacgcc agccattacc cacccacatt tgtagcggtc tatacgcaaa
      721 tgtcacaccg tatgctgttg ttgggtcatg tctggcctgt gttaaaaagc aaccagcagg
      781 cgcttctgct ggtccatatt catctacttt gccaggccat acaggagcac cgcgctggat
      841 attttggaca taacgattat ctgattcgcc ttttgtatat acgtttcctg atgttaaata
      901 acgggcgtcg aaattaccgt aattatccgg aataacttgt ccattaacaa caaactgaat
      961 actgccatcg gtattacgct ggctgtataa atgccatccc tggtcgtcat ccagctcaat
     1021 aaccgttggt cgatttccgt caccccacaa atgaaattga gcattcagca cggagttatt
     1081 tgagctagtc atggtcattc gtttggcatc gcctgcgcga atggctccca gaacctgcat
     1141 ttcaccggga gcgacacgaa cggtgtgctg gctattcgca aacgtatcca gtatcccatc
     1201 gccgttctgt ttaaaaccag tgtcattatc accaagaacg atcgaattgc cgcccagcgc
     1261 attatcagta ccaatgctta gcggaccgtt aagacgccct ccggtaatcg gcaatgcacc
     1321 cacatcactg gctgacggtt tatttgcggt gttgtagtca ataacccacg ggcgactggt
     1381 attcggtaca gttccccagt cctggcgctt tgcgttcgcg ccaatatggg cataataatg
     1441 ctgaaaccag acgtctccga ttttctcaac aaacagatat ccatagctgt acaacttgct
     1501 gccacccgga taggtgggaa aatcaacgac cgtatcagaa ttcgacaccg ccaccttcca
     1561 ccatccgggt gcattagctg atgccattgt gccgttatcg gtaatttctc caacagcatc
     1621 ggcggaaatg gcccccacat ctgacgccca caaagtgata tcaccggtca gtggtttact
     1681 gttaacccgc cgtgtcgccg ggacggcatt ttttgccaga tttatcgttt cgcctaaacc
     1741 gaggtatgtg agaatatccg caatactggc ttttccgatg atgtcgcgcc caacagaagt
     1801 aagatctgtc tgtccggctg tatcattccc cgtgaaatac ggaagtttat ctgcaccagt
     1861 agccagacca gcgagcgccg tcagcgtggc atcaagagtc tgaaaatcct taccgaacgc
     1921 agcggacatt ttggcgataa agccgctcag gtcaccatca tcgagtacat cctttccgct
     1981 cttactggct gtgtactgtg ccagtgctgc agcgatgaag ctcgcctgac gcagcgcttt
     2041 atttacctgt gcacttgatg ccttgcccgc agtaaaacca gacaggagcg ccggcagcgc
     2101 ttcccagtca ggctgtgatg taacattagc acccttaccc gtcgcaaacg gtttaaaatc
     2161 atttttagcc atcagagtaa tgtcccccat gaaccggcat caaacccgct gatatattcg
     2221 ttatccatat caaacccaaa aaacctgttt ccttcagaag gcgtttccac cgaaggtatt
     2281 tcaatacttc cgccccatac accagcggcc tttaccgtca gatacccttg tcgtatcgca
     2341 gcaataagtt cgagagagac cgatgaaata tctgtttcag gaaaaaccca gatacctatg
     2401 gtcatatcct ggttatcgac gatctgcatc ttcagaccgg acccgtccag tgcggcgtca
     2461 agaatgggag gcagggagtc gtttcttccg tcccagttgt taattgctat cttcgttttt
     2521 agaacgatgc gataggtttc atcgctcagc gaggtataac ccgaatccgg atcatatggc
     2581 ccctgccaga cgccctggtc atatccaagt ccgtcagtgt cccaactgaa atagacaccg
     2641 cttattggct ggcttacaac acggcttaac cctatccact ggccgagaat atcgagttgt
     2701 attcctgtcg cataatcaat atcaaaagcg cttattagcc catttattgc ggctgaggtt
     2761 tcagctaacg gcctggtcac taaatcgatg tgttcaacga atttaggttt tgtcgcatga
     2821 tagttagtaa ttaagtccgt atatttgctc atgctgccac cgtaataatg atattttccg
     2881 gcttacagga ggcagattcg tcgtaagcaa tattaatatt cgccgcatca acggtttcag
     2941 gagatttgcc gatcagcaac tcctgaatat cgtaatagcg cgcattacca ccactgacga
     3001 ccccaaggtt agcaggagaa taaatccggc tcagcagtac ctggtcacca atcatcagtc
     3061 tgttaatgta atccgcaaca gcctgctgaa tctgcacacc tatctgagag gtgtacccgg
     3121 caaaaacttt taaggtgatt tttccgtaaa cagggacatc agttggtcgc gaaaaactga
     3181 ttatgtgagg attaccatat ttatccggta cggttacgga tgtttttccc caggtccgga
     3241 ccccctgccc tttatttccc cggatggtcc tcgctatttc ggttacatcg ccaccatcaa
     3301 caatggccga gatggaatgc ggaggaagcc cgttaccgtc agtctttcct gtatcatttt
     3361 catagagctt gtggcgcgtc acaccagcaa tattagcgat cgccccgtcc acgccttcaa
     3421 atggtgtgat ggatggtatc gcgacactct gcccctgcct gatgcgcagt tctgcgtccg
     3481 tttctgcagg tgcgccaacg gtggccgctg ccgggttggt tactgacgtc cagccacggg
     3541 tcggtgtatt gatagtggta atcgtcccgg caggagctgc aaccgctccg cttttggaac
     3601 aaattgcagt tgccgtcacg gtgccatcaa caccaatcac cactgaatcc ggaagacgcc
     3661 agatcacgtt attggtgtct ttcacggtgc cgttcgtaat ggttgttcct gcggtgccag
     3721 tgagcagtaa atccacggta gagttcgttg cacctttgcg cgcgataccg ttaattttta
     3781 cgttactggt cagcgctgcg ccgtaacctg tagcaggtga gaagcagtta tagacggaaa
     3841 tggctgtgtt attggcatcg tgaatagcta gcgccaccag cgccaccatc tggccgtctt
     3901 tgctgtccgg ctccagataa gcgtcactac cataaatctg ctggaaatag ctcgtcaggg
     3961 tatcgagtat cgtctggtaa tcaggcgcac tgatcccctc agcggttacc gttgccgata
     4021 agccgagtgt gtccaaattg agggccattt atgcctcgct ggttactgtc gttgttccgt
     4081 agatagtgtc gatttcagcg aaaaactgga cgcggcgcgt cgtcgtgttc actgtggtat
     4141 tgaaagagag gatggatttc acgccccgcg tttcgaggat gcgcttgcgg atcgccagat
     4201 tgtaggtttc cggcttttgc ttaccgagca cagactgaat ccacggtgtt ccctctgtct
     4261 tatcgaggaa ccactgcccg taccacaatg caaatcgtgt ttttaccgcc tgcgcgacag
     4321 cttctggcga gttaatcagc caggtatcat cgccactacc aaaagtgtaa tcaccttcgg
     4381 tatcttcgcg tcggtatcgc atgtctgacc tccttattca ccaccatcgg acggcaccaa
     4441 tcaggctcga aagcccgaaa aggaaaaata caatccatat aagcaggaat ttccagttgg
     4501 gtaatttttc gcccataact cgcaactcca ttatcagttt gctaaaatca atcacatgtt
     4561 ctcccttgcc atcctcaagg tgtagaaagt aaaaagcccc gaagtgttag cgcacccggg
     4621 gcttttgtct ggttggtagt ttttaattcg gcgcgccagt attcccgcca cccgtctgaa
     4681 cgccgctatg agtgtgcgtc atcaggctct taccgcccgc cttcacatcg tttgtcaccg
     4741 tgacaggacc gagcatcgtt gcgctaccgc cgccctcacc catcccctgc gacagattgc
     4801 cgttaatggt tacgtcaccg tttagcgtaa tgatgggtga tgtgatcgtg gttccgcctt
     4861 ctgcagtagc cgtcagcgcg ccgggggttt taacagtaac gttatggcct gcggccactt
     4921 ccacaaaagc agccccatca tcggtacgca attgtgcggc gctggtgctg attccgctta
     4981 ttttctgcgc ctgcgactgc ggcccgacga tacagaacgc atccgataaa tcatgcaccc
     5041 gatcgtcgac aggctcctgt accccgccgt tctgccacca gaaatcgatg cagcgatcgg
     5101 caaaaatcac cagacactca tcaccagctt taaccgggaa cgttagcgtg cagccaccgc
     5161 cgcgaggaaa taccaccggc acatccacca gcagcggtaa tgtcgtcgac tggctaacgc
     5221 cattcgaatc cggctcatag cctttgatag cgggttgaac aactgcggtt acggtgtcgg
     5281 gatcaaatga ctggacgatg ccaggcattg aaactcgcag tgcagacatg acagaaccaa
     5341 caagccttgt atcagcctgt tctttactgc cgagttgaga ggaaagtgaa actggcatat
     5401 tttctccaga cataaaaaaa cccgctcatc ggcgggcttg gtatggtagt catagcttat
     5461 gctgttaacg agtcgtcggg gttattcatc attcggtcca ctagagcatc tatctcttca
     5521 gcatcttgta aggcactaat tgccgtaatt cgattaattt tgcgttcaag tctgtaatca
     5581 gcatttacgc gctgagcatg taacatcttt aacttaatgc caattttacg gactttatca
     5641 acatctacgc cgttaacttt agcagcctca ccgttacaaa aagctgtata gagtcgcatg
     5701 tgagaaccgc caggtaatct ctcaccatca gtatcatggg taggcgtcag attgttagtg
     5761 attctgaggg ctgaatgata catgccgtag tatgacctgc tgatagcatt acgtgtccat
     5821 tgctcaccat tgtgctgcaa tgattctctg gctaattcga gaaaacaatt atgcataaca
     5881 ggcattagaa gtctcctgcc tggaaacaac caacacactc tgaattttcc aaaccagcag
     5941 cgatgagttc attggcaagg tcgttattca cttttgacaa aagtgctggg tcgtcagttt
     6001 taatttctac gaaaaatgtg ttcagctcat tcatgacata aaaagcatgc gcaccagcca
     6061 gacgtaaacg atacttttca gcaatagtca tcatcaattg gccgatcgcc ttaaggtcat
     6121 gagaatgatt ctcatgatcg ataagataat caagcgactc attacacttg agcaaatcgt
     6181 ctgccttagc aacttccatc gcattaagca taggcattac ctttttcagc aaatctaaat
     6241 ccacccaata cgcagcattt atagccactt cagaaagaat tcgaggatta cgcgagttga
     6301 tcgctctctt aataatctcg tattgcttaa cgtgataccc cttgtttctc aacgcaatcg
     6361 tatagttaca aaacgaaaca gaatcgtccg gggctatcgc caatgacttt tcacaaaggg
     6421 cacatccctc ttcaacttcg cctaaaacaa gcttagctaa tccctcgata gaaagccctt
     6481 gataatattc aggaacattc ctggcgtcac gaatgacggc atgaatttca aactcactga
     6541 gtaggttttc tccctgagtg agtgagggac caaggatctc taaaagctct ccggatttag
     6601 gctgcgctaa actcatttag ttgtaattcc tgactgggtg acatcaaagt tgatggcaaa
     6661 acgccttcaa aagtatctgc agtgtaatgg gtaaagttgg aaaacgacag cacgatgcgc
     6721 acattttgct gattttcaga aagtttggtt agctagaaat gtcaatcgat ttagtttcac
     6781 cgaggcacct tcttacaagg aaaagcgcgt tcacttcacc ttccggcagt catacgtcca
     6841 gaactctcgc ggctcgtcca tatttttgcg gataacttca acattgagga tcggcttgcc
     6901 atttctggcc acaaagtcca tccctaacca acgtccatta cccggaacca tccattggat
     6961 gttcacattg tcataatccc ctttttgttt gagaaaggtg attttctgtg tctccggttt
     7021 ctgtccatta atccttgcaa gtccgtcttg cgctttccag ttgatcgtga atggtccgca
     7081 cccggtatca gcaaaggaag tgaaggagat acagacaagt aaagctgcca acaatagtct
     7141 tttcatgtgt atttcgccgc atcaatccct ttcgagttaa gcaattcttt gccatcttta
     7201 gccaggcaaa gcaggtccat ataccacgcc tgcccgcgag tgtcgccagt ataatcgatg
     7261 ctgcccacaa tgtaatcacc gtcagtatta atgctggcag gctgtgacat gccgggcagg
     7321 ccgttaacgt agagattacc gtcgctttcc gattcatcca gccgtgctgg agattgcgct
     7381 atctggtcat tactcaaaga ggtccggtag acagatgcct gatccagacg aataagccca
     7441 cccagcttaa tgtttggatt aatcaggcac ctgacgttta cgcctgcacc cattgtttgc
     7501 tgaggcctac cgattagccc tgtattggca ttcagcaccg tagcgacacc gatatagtta
     7561 tcttccggca caatgttgac ctgattgttc tcataccacc agtaagcgtt acactgtccg
     7621 gcgatatgat tcatcagcct ggctgtgctc tgatagacaa cccgcccacg ggggaagacc
     7681 gtctcaggca tgtcaggaac tgcacctgac tcgataccat aaggcccgaa tgatttcatg
     7741 cccaggctga aaagatcact gtacttccag ccggcagcca ctgtggtttt cacactggcg
     7801 ttcaggtggc cttcccaact gtcgatacac tgcaacatga tccaactgtc tgtcgcatta
     7861 tctttcccgg tgacagtaaa acggatatct ccgttgaata tcataccaac gttttcatcg
     7921 ggataattac ccgttgcatc cggttgtccc ttatatccgg ctataacctg tatacgcgag
     7981 aattccttct gcataatccg gttctgagtg gtaggggaca ggttataaac cttaaaattt
     8041 ccaacgaatc cattaaatat ggtcgcaggc attttctgaa tattgaaagt gactttaagc
     8101 tcagaaattt ttatcccgtc gcccttatcg tcaaccagca ataattcaaa gtgacgcatc
     8161 cagttttttg acattgttac tccgtgaaga catagaggtg tgagaacgtt ccgagatcga
     8221 attgcgtcgg gttttcctgt cctgccacgt cgcagagtac caccagcgaa aacccgagat
     8281 tcatatatcg atactgcgcc agcaggtcag cccccgtaat catcggcata cctgagataa
     8341 tggcggaacc attgctgtca gcaagatcca gaacccagta ctctccgcgc cagatgacag
     8401 acaggtgata aaccgtaccg ttaattgtgg tggcaaaagt ctgattatca gcgaccagtg
     8461 ggatttctac ggcctccatg aatcaccttc ccagaaataa attgctcaga tacccatcga
     8521 cagtggtgac acctttttgc gccatctgtg gcagcgattt cagaatggaa ttattcggcg
     8581 gtaccgttgt tttggtacct gtattctgta cagcagacgt ccctactccc tcggtcatat
     8641 tgtttttcga ggcaaccctg attgactgcg tggaggtaat aatcacctcc ctgagggtaa
     8701 gggtcgccag aagcacattc tcactgctct tgtcagtcgt cacctccagc gtttttatca
     8761 acatattgtt gtaaatacgc ttgccggttg tcacatcgaa aggaatacga tcccgctgca
     8821 ggttaagcag ctcctgatac agttctttcg ggctcagccc cagtgaaaga ccaatagcgg
     8881 aagtatcagc aaaatcaagc agcgatccgc ctccggaaaa tccggtttcc atcacaactt
     8941 ctgaagggcg cctgaatgcg tgttctgata tgtaaccagc gccctcacca ctggcaccag
     9001 cattcgtggg ttgttcaacc ggatgttccg taatttccag agcgtcagta tgcttttcgg
     9061 taataaccac atcaggaata attattccta tcgagcgggt tcgctgctgc agcaaaacag
     9121 ataaaaaatc cattacgcag gtcctttcaa ttgctgtacc gccctggcat tgacagcacc
     9181 ctgcttgtca gcgatcagat tagccgcttc ctgaggattg ttcacgccgt ggacatttat
     9241 aacagtctgc tggttaaggc taccaccagc ggcctgatac gccagcgggc tgttccagtt
     9301 tgaataccct tctttgcgcg ccatcgactg catcagcgcg gccatagttt ccgggttggc
     9361 gaggttcaac acagtgttcg gtgaaacgcc catccatttt gcaacatcct gcgcatactt
     9421 tttcgggtcg ttgttgtcac cagccggcgc ccaggtactg acaatatcct gaatggtctg
     9481 taatgcccgc ccggttgttt tccctgtaaa gtagcgcata agctggtttt tcatcgcctc
     9541 ccagccctga agggcggact cgaagaaccg gaagccgtta ccgcccaccg ggcgaatgtt
     9601 acccggattg ttgttcctgt cggctaaagt gcgctttgcg gattgtgcat gttgtacagg
     9661 ttctgctcca ggaatatccg gctgaatatt agcgcctttg acggtgtggg gattgcggcc
     9721 aaaatcggta tcaatcccca gtgcacgcat tccatcgcca atgttttgtt tggcataatc
     9781 gatagacgac tgcgcactgg cgacgatatt ctcccgatcg tcatacaggt aagccgcgta
     9841 ggccatccag ccttttaacc acggcggcat cggtatacct gccagtctgg caaatgcgcc
     9901 cgttaccttg ctaatccacg caccggcgat aaaggtcgcc agcagctcca gtgacgtttt
     9961 ccagccgcca atagagtcct taagttcgag caggtgatca cggagccaga ccatcgcatc
    10021 cttcgctttg tctatcgctg gctgccattt ttcccagtca ataagactgt taccgccttc
    10081 tttccatgtt ttgtagtctt cccacaagag accgaacgcc acgatcagac cagtaatcag
    10141 ccctacaggc gacatccaga aagtagagtt aagtatccgc atggcgacaa ccagaccacc
    10201 gataacctct atcagggttt tcgtttcttt atccagtttt ccccaccagt cgataatatc
    10261 ccctacacct tcaacaattc gaaacgccac gcgaccgatg atatccccga gcgtcagaat
    10321 accttttatg gctttcgtca gggtctgctc gatgcgcggg aagttatcca ggatgtggcg
    10381 gcgcagcgtg tccagcgaac ccgccagacc accagcaaga ttagagccga tcttgtcacg
    10441 ggccaagcct gccatcgcgc cgaactcgcg cagggaggtc atgaacctgt tggagctttt
    10501 ggccgcctcg tcagcattga aaccgatggc ctttgccatc gcgctgtact ggccggagaa
    10561 tccccctaaa ccccggcgca tcgccataag ggtattttca tcaatgccca gcatctgcgc
    10621 atactggtta gcccggtaat acggcatgct gctgagctcc tggccgacgc ccgtaaaaat
    10681 ggcggccata tcgcgcatat tcccgctggc gtcccgggtc tgtacgccca ggcggttcag
    10741 aaagccttcc gcgccgggat tattacgcac aaaccgggag aggctttcca gcgaagtccg
    10801 cgccgcgtcc acactaccgc ccacctgcga aactgcgtag ccaatcgact gaatcccctg
    10861 aaccgtcgcg ccggtgcgtt gagatgccca gtagagatta tccagaccgg aggcaatttt
    10921 cgccgtaaac gcaacaacgg acagcgccgc accttccacc gccagccctg tttttatggc
    10981 atttgcggtg acgccagcaa gaacagattc aaatttctcg tatccggctt catcaatgcc
    11041 aaatccaagg gagacgagaa aatctttaat agtctcagcg ttcattaacc tctctccatt
    11101 tatctacccg agcatcgtta tcctcgcgca tgtcgaggta gtcattgaga agcgcgatgc
    11161 ggcagagatc taccgcgccg ctgttaaggt ctttctggtc aatatggaag gcgagaaccg
    11221 ggcgaagaat aaaatcttca ccgcccggca ggctgttgaa ggttattccg ctggcggggt
    11281 gggcgtcccg ttggtaggga gtccttgcaa aaaatttccc agagaatcgg cgaccacccg
    11341 cgccaccagc tgcagcatgg tcagcaggtc gatatcgtca aacatcaact gaccgctgtt
    11401 aaacaccggg gcccatcccc ccatatgttt gcgtgatacc acagccaggc aaggatgaat
    11461 aatcgcgttg gtatcttctt cggtcaggga agacagttcc tcagcgatac gcggcagcag
    11521 ggtttcaaac accggcttaa gcgcatcaaa cttagcgctg tcgattttgc catccgcagg
    11581 cagaagggag cgaatgcccc cgaaatctga catcatgccc gccagcaccg gcagcaattt
    11641 acgggtgact ttcagctggt caaaaacgct gagtttcgcc acgcgataat cgtggccttt
    11701 gactgaacat tccatctgtt aaaactctcc gagtacctgg tcgattttgc cgcagtcaaa
    11761 tacccagggc atcgtattac cggctttcgc gttggcgtta tccggctgtt tctggaaggc
    11821 cacactgcgc gccgtgatga tgtctccgct caccttattt cggatcacaa tgacgttgtt
    11881 tccccaggtt cctgaggact gactctgtgc gttatacgcc agcgacagtt ttttgtttgt
    11941 cggcgaggtc ttcagcagat tgacagttac cgtaccgctt ttatccgcgt gcaggctgtg
    12001 catcacttcg ccgtcagcac cgatggtcat ggtgtttttg gggccgccca ttgcaacggt
    12061 gatcccctcc tctgaactgg cggaaccgta gcccaggtca atctcgccag tcgggccaga
    12121 aatggacgcg gtgacatcca taaaagaata agtagccatt cattttcccc ttagcgaacg
    12181 acgttgatct gtacgtcagc gaaatgcact gcgccagcca gcttacagga aacctgaata
    12241 accggtgcct tacgtgcttc acggtctgcc tgcgcctgct cggaaatcgg ctgcgcgtag
    12301 acgtaatacc cttttgtcag cgcgtctccg gaatccagct gcccgattgg gccaccgttc
    12361 catacgccag cagccaccag cccgttcgtc acggactgat ccatagactg ctcaacattg
    12421 gacagaagac gtgtaacacc cgcatcggtc tgaggcactt tggttgtact ggtgtacagc
    12481 aggttataca ggttggtctg aacgtagttc tgcagccagt cgagcccgtg gcgctcatca
    12541 aagaaatcac cgctggacat gacgccctgc tgcaggattg ccgtatcgtt ctggtagtac
    12601 acaaacacgt tgcagttctt ggcatccagc gccgccgcct gatcagtcgt cagggtttcg
    12661 taagtgatcc ccggctcctg tttaaatttc agggtaatgg tggtattgct gccgttgaaa
    12721 ttcaccgtaa acgcgcggcc aaacgcggac agcgcagcgt acttgctgct ggaagaatac
    12781 tgtacgaacg tgcgcccgta ttttgccgcc ttcagcttgt aggacagatc cccggttgaa
    12841 gtggcgtcaa aggtggcggg atcgctggtg gtaattgcca gaatgcggct gacgcccgaa
    12901 gcttctacgg ctgcagcaac cttcagccag tcgtcatctg caatatcctc tttgtctgca
    12961 ataccgagac cataccagtt ggtgtagccc attacggcgt taaccgcatc catcagcttt
    13021 tcagcagcac ccgcctcacc cgttgccagt gttttagccc agcgacctac atacacctct
    13081 ttaggtcgtg gtgactggga gaaatagact gttgctgctt catattcggg gctgtccacg
    13141 ccgaaatcag atccgatgtc ctcctttgag gagtagaggc gaagacgctc tttcaccgga
    13201 atgaccgtgg atgtcccgag aataagcagt gaaccaaaat ttcgaccagt agccgcgcgc
    13261 ggcccaatga tcacgtcgac attaacgacg tttgatacag gtaatccctg cggcataatt
    13321 taatctccga agaatgaaac tggtgcatcc accagcgatt taatgccgta ctcgcgcacc
    13381 accttgcgac gaaggcgcac agtaatgtcg taacggcgaa cccactgctg gttgataagt
    13441 tccgggaaag gggtcagacc ggtgtagtcc cccatggaca ggccaagcgc gttcagttcg
    13501 gcgttgtttt gcgcaacaga aataccatcg cgaaaacgtg acgcaaacgt catgcccgcc
    13561 gggccataaa atgacgccat gcactcaaag gtttcatgtc gccagagctg agcgccctct
    13621 tcagtctggt tagtgaatgc gggactgtta tctatgggcc atccggtaac gccgaacgcg
    13681 caccagttcg tttcagctgg cagcagtggc ggctgatctt tctgccatcg ggggcgaacc
    13741 attccagtcg gcaaaccgga aacgttgcgt acccactggc ttaacagcct gtcgagcgcc
    13801 tcgtcataat ccggatcgcc gctgacaggt gtaagccatc ccggctccgt actggaatta
    13861 ttgctcaacg ggaaatcctc catcgaacgg cagcagctcg caatgcgcct gtacaaagcc
    13921 ggcgccatat gcggtgtacg ggtcgacgaa tgtcacacga taatcacggt tctgatacgt
    13981 cacgatatcg gcatcacggc cagtctgccc ctgcgtgagt cgctcagtcg tcacgataag
    14041 gattgctcca ctgataacct gcccggactg catgcggcgg ttttccagtg aacggtcaac
    14101 ggtaacaacc ccggcaaact gcgttttaac ttcgctgtcg ctaccaatcc cgtcttcgtc
    14161 cactgtctgt acccgacgcg ttacccaaag gttgaagtca caaaaatccg ggtcgaaaag
    14221 aacatcggtt acatcaagag tcggcatctt tatccctcac tacatgggtt attgaggcga
    14281 gatatttgcc agtatcgtaa agaggcttag ccaaagtggt gcccggagat tcaccagcag
    14341 cacgccgcgc aagttccgct ttcgcacctt tacgcccacg gcgcgcacgc gcttcaacgg
    14401 tgctatctgc aagcggagta aaattggcag ctttgatgtg atttttcacc cctcttgcag
    14461 ccactgtacc tgcgcggttg agtgctcttt ccgctcccgc cgcattacca tcaagcgcag
    14521 cctgtgccgc agctttaagc tgtggcatcg tctggtcttc aactgattta acgccgggta
    14581 caagatgcgg acgtggtggg atgttttgtg caggtgaacc gtattcgttg atatacccaa
    14641 tcccggcatt accgaacgac acatcatccc gatcgctgtc ttccgcaggt ataccgacca
    14701 gcacatcctt tttggttagc gactttagcg catccagtat tgcctgagcg ttatcaaccc
    14761 tcgttgttac accgcttttg aaactcatag ctggcgtccc cctgcaccga acatcgtgat
    14821 cagctgataa aattcagcgc cataccgggt gttattccag aagcctgcgt cagggtttag
    14881 cgtcgcgctg gtgtcatagc tgacgcttac cttgtcaacg gacttggagg actgaacacc
    14941 attggttgaa ccgcccggac cgccaaccag catcgcccgg ctatctgccg cccagagcgt
    15001 catatagtgc gcaacgaaca actcggcaaa gtacggaaac aactttttgc cggtgacgtt
    15061 ttcgctcagt agttcatcgg ccagattcag acggaactcg atttgtgctt cgggatatct
    15121 ggcagggtca gcaaactgcg ggaagtcgcg gcgaaaatca cttactgttg gcaggctttg
    15181 attctttggc atctttcgcc ccattaccgc cagtccgggc ggaagtaatc tgcgcctgca
    15241 ggctgtcgtt ctgctcctgc agcttgagca gagcgtcttt cagatcggca atcagtttat
    15301 ctttatcggc aatctgcgcc tgaaggctgt caataacggg ttgctggtca tcagtttcat
    15361 tcgatccgct ttcggaaagc tcagcgtgcg cccgggtaaa ccagtgcgac gcgacctctt
    15421 ctggtacgtt atgccgtccc cggccaaact cctgttttga ctgatcaccg agcgtcagcg
    15481 taaacggggt gtgaacatgg atggtaacca gcttttcttt cgccattttt agtttccttc
    15541 tggccccttt cggggccatt ctggttatca gataccgtcc acgtaggaca gggtttcttt
    15601 gtacactggc tcaaccgcac cgagcttgcc gtagtaggtc gcaatctggt acagaccacg
    15661 atactgaaca ggaacgcttt gcagcggaac cagtggatag cggacgtatt tcttatcgtt
    15721 ggtgtaggcg accatacggt ctttaccgcc aaccccgcgc cctttcagcc atttgaccgc
    15781 tttgatttcc agcggaacgc cattctggtg gaaagcgata gtgttcacag ccagataagt
    15841 cagcagtgac tggttacccg cttcggaaac cttacggctc gccagcaatg aatactgctc
    15901 tggcggaatg cgcagatcag aaggcacgac ggaataaccg gatgctgccc aggcattcga
    15961 cagaatgctg tttacgctgt cgaggatctc atcgttggtg gagttagccc aggtcttcgt
    16021 tgcgttgttc agcgtcacac caacgagatt cgtcagacct ttcaaaccaa gcgcttcgtc
    16081 tccgacgtaa acctgttcgt cgttatccat ctgccattta agctgcatcc cgtcgtactt
    16141 ctgagtgtcg atcggacggc ctacctgctg tgccgcagcc agctcaacaa cagtccatcc
    16201 cagctccatc ccccaaaggt tcagcggatt gccgtcttta ctgatatcaa cattaacgcc
    16261 agcaatggca gttgaatctt tgcctaccca gtttttacca ttcggattag cgccagaacc
    16321 cgccacgcca aaactggtat tcgtccagct ggaaatgtca tctgcgatag agacgtcttc
    16381 gcgcaactgg atatcacgtg tccaggtata acccaccagt ggcagattca gcccctggtc
    16441 gagtcgctcc agctccccga tgagaaaggc accggagcta tcaacggttg cctgatcaaa
    16501 agtaatcatt cgtctgttcc ttaaatcttc caggagattt ctgcgttgcc gttagcgtca
    16561 ccggcccccg taaaaaaagc atcaggtaac gcggctgttt tgcctgtcac ctctgccgcc
    16621 gtgatcccac caagcggaac cgggatggaa gcatcggctg ataccacgat gtacaccacg
    16681 cctccttttt taacggacga agcatcagta cccacgttta ccgtcatgta cccacgcttc
    16741 atggcgtcgc ccgggaaatt cttatcagta cccacctggc gaaccatgtc tggctgcgat
    16801 gtggtcggat acggacgaac gtagataccc ttcaccttgt cgacggtgtc accctccgcc
    16861 agcggcacga aaaagccgtc agcgtcgtat ttgccagcca gaccatacgc tgcgaaggcg
    16921 ttatcggatt taaggatcac cggttcgacg gttaagtcct gcgggcgaga gatagccccg
    16981 gcaatgccaa caggcatccg gtacagatat gcagtcattg gattatcctt tgcggttaga
    17041 ccagaagtcg gcgttttgtt tgttcaggga agcgatgctg gtcatgccca tgcctggacg
    17101 ttgtgcatcg cccgtggtgc tgcgggtgtt tctccctttt gcaatctcag atacggcgtt
    17161 aaacgccata tcaaccgatt gtttaggtaa tttgcggata tcagcgtcac cgacaacctg
    17221 gcgaaccagt gttttgtctg cggccgccag cacatcacgt ttaaatgcgg tcggtttcac
    17281 cttacggctc agatcgatac ccgggataat gacttcagcg cgataggcag agtcacccgt
    17341 aatcgtggtt tcctcttcgt tgtcctcgcc gtcgccggtc gggtctttct tatctttatc
    17401 atcaggggtg tcagcattat cgcctgttgc cgttccttcc agcttagcca gcagggcctt
    17461 gagcagggtt ttgatatcgt cctcgccgtc gccggtcaca tctccgccca tctccggctt
    17521 tttgtccggc aatggttgtt gtggtgaaag gttaatgttg agattgacgc cgcccggcag
    17581 atcaccttca tcccccgtta cagccgctgg cgctgagtcc agcagttcgt tcatggtgtc
    17641 cgagtcacct gttttgatgg ccgtgcgcat gcgggtccac cagcttttct tttgatttgc
    17701 cattgtgtct ctgtctccaa ttgcacaacg atttccggct ctgcctttgg ggacaagagc
    17761 cacatggttt ccggtaatat cgacctgctc agccttaccc ggctcagcct gttcatattc
    17821 cgcgtcatag ccacacgaca cttcgcgcag accatcttcg ataagctgaa tggcgctttc
    17881 gtctttgacg ataaggtcag ccagcatcaa atcagactgc tcaccagtcc cgcgccggac
    17941 attctgaaga tgaccgaccg caagctcttt ccagttctcg ggattgacca accggacgtt
    18001 cccgttttca tcctccggat gcaggatcgt gatgctcatc ccttcgaagg aggcaagcgt
    18061 ggccggatgg aatacctgct caggagagcg cgttacgact atctcaccga acttgtcagg
    18121 cttgaggttt ggcagatcag cagcgccgta aagctgctta cccgttcgac ctatcggcac
    18181 gtctctacac agcagcgagc cgtcagccag ctgatagcgg gtttccccca gccgggtatt
    18241 gaaaaaatat ttcatgtttt acctgcgatt caggcgagat aagaatgagg gttggggaag
    18301 acgatttctt tataacagcg gcagttcggg agctcgccag cgtgaccggt catgccgtca
    18361 agcgttgggg gtcgtcccca ttcgacaaac ttcccttcca tctcccgatg agaatgccgg
    18421 acgtcgccat cttcggctgt acgccagata taaccattcg agccgattga cagcgctcgc
    18481 gcctgatcga gcgcgccggt tgcacgtcca agttcggtac gggcgataag gtcagccctg
    18541 gactttgcta tatcacccga tgctgcaatt tctttagcaa aatgctccgc tctcccaccg
    18601 gtcacaacag cttcaatcgc ccgattctgg atgtcgtata ccctgtcagc agcctcgagg
    18661 ggtagcgatt taatgtactt aacctgttcg gcaacgatgg atttcatcac ctgccctggc
    18721 ggggcattgc tcaccagatt gcgtagttca cgactgatgg ttttgctgtg tttccgccac
    18781 tgctcatcat tcttgcgcac aatgtcagcg gtaaagttct cagcaacctt cgtcgcccac
    18841 ggcgttataa tttcgctgta gcgctccagg gcctccatga tttcggtgac gctatcgttt
    18901 gaaccatcgt agtgcccatt tacgatatcc ccgaccgccc gcgctatctg ccgtaggctc
    18961 gttcgatatc ggatctccgc ctgtcggctc tggcggtttg tcgacaagtt cgccgatgcc
    19021 tggtggcgct tcgtcttcgg cattctcgat atcctcgtcg gtaatggatg cgccgatgcc
    19081 agtaacatcg gagttctcac gcaggtcggt catagcggct ttggttgtca tcagacctgc
    19141 atccagcgca ttgacaatcg ccgttgtggt attcacagcc accgttgagc ggtccacatc
    19201 tgacatctgc catagcgggt taaactcaaa cgtgaaatcg tccggcagcg gcttaccgag
    19261 ctccgaacga tgcataatgt ccagcacccg gcgcactggc aggcgtaagc gacgctcctg
    19321 caatgaactg acccggtcat aatagttggc aaggtctgcg tcacccgttg agaaaccttt
    19381 aggggactgc ccgaagaggc gcaccaatgg aatgccaaca gcaccgctaa tctgctcggc
    19441 gaactgcgaa agaatgtcat ccagaccgct gaaactgtac tggtgggttt cgaaggtatc
    19501 cttggcatcc attagcgtca tgccttcatt gctctgaaac tggcggatca gatcaatgtt
    19561 tttcagcaac gcctcgaatg ccgggccgcc cagtgcaata agctcacgga gtttttccac
    19621 tttgtaggtc cgcagatgcg ctttgtagac cagctgcgcc gcaccgacag tggcgctgtc
    19681 gaacgcagta agccgatccc agatacgctc tacaaccgac attccccatt cgttctcggt
    19741 catcttctgc tggaatggca gcgtcacccc atcgaagcga atcaggcggc tatggtgaat
    19801 acgccaggcg gggatgcccg ttgcggtggt caccacatca taaagctcgg gcttgccgag
    19861 atttggcccc atctctttaa tgcggcgcgt cagtaccggg ttaatcatcc agcggtcgag
    19921 cgggagaata cccttaaact tgccttcacc aatggtttcg agccgtagcg gggtcatggg
    19981 cgcctgacct tctatcatga tgaagcccac cgcgccgccg tagagacgag accatttcag
    20041 tacgtcgttc agcgcatccc agatttgcaa ctgatccagt tgcgcttcga gagtgccacg
    20101 gtcttttgcg tcaatctcag aagtgatgcg aatgcctttg cgggtcatgt cgtcggggat
    20161 agcatctacc gcttcaccga tgagccagga tgagcgatag gaccattcca ccagcatacg
    20221 gttgcggctg gtgaagttcg cccggtaggt cgatgcggag tgctggttag gcgtctgcat
    20281 ccccacgcgg gtgacaaagt tctcgtagcc gtcggccgtg gcctgcaccg ttcgtcgcga
    20341 ggcttgtttg tttcgtgcca tcaggcctgt ctccccaact gttcccagat gtccagcgat
    20401 gtgtcggttg gcgcgaaagc cataatgaaa gcgtcggcga cgtttggtga cggtatatcg
    20461 cgttttgcga ggtctttttt actttcgacc atcacccgtc cgttacggtc gaaatcgcga
    20521 tgaggcgttg tcagttccag tttcagcttt tcaagcaacg gacaacgaga atctatgctg
    20581 atcagctcat ccacaagata ctgttctccg ttgttaatag cgttaaacgt atttctgaaa
    20641 cggtcagcca ccagccacca cgcctgcgcc ttaagatttg cgaaaaagtc tttgttgggg
    20701 atgccgttgt attcgtcatc tggctcatgc acacctgcac cggcgttaaa ccgctggtaa
    20761 ttcacacgtc gcgcgtatgc gttctcacgc ttccggtcat cgttaatttc cgagaacttt
    20821 gcgcccgccg acgcgccaac accgattgag tcgtaaacga tatctgcatc gcgctccatt
    20881 gcagcctggt aagtgcgctg gcaactcttc agcaactcgt cctctttggc cttccattca
    20941 tcggcccagt agataactga gccataacgg tagacgttgg cgcacttatc cgcgccactg
    21001 tcggcgacat cgaaaccgat gcgcttacgt ccttcaggac cgaaatccag aaccttatgc
    21061 gcgtcaacag ccgcttcaat ccacgaaagc ttaataattg ccgcatcatc atcagactct
    21121 ggtacgccct cataaacatg cacaaaccct tccgggtcac gacgccttgc cgcatcgata
    21181 accttcagca tggtatctga aaggaatgga ttctcgtcgt agttgatttt gcgaatcagc
    21241 gtatcttctg gcggatcgac cacaaagtta cgccacacga aatcggtgac cagtccaggg
    21301 ttaaaaataa accaacactc tgaaccctct ttacggattg tcggctccag tattttccat
    21361 tgatattccg tcagtgcatg ggcttcttcc agccacaaca catcgatccc ctccagtgac
    21421 ttaatttctt cgatgttgcg ccataaccca taaaaaacaa attccgagcc ggtaacccgg
    21481 ttaatgattt tgttgttcag aatgcggaaa cgatgccgca ggccaaaccg gtctatctga
    21541 attttgagaa gcgtgtaaac cgattcttca attttgttct ggatctggcg agcgcagcaa
    21601 aaacgcaggc tgtatttatt tgccaagaat attgcaaatc cggctgcatc ccatgatttt
    21661 gacgatgacc gcccgccata gagcacttta tttcgcgcct gcgtggtcca gaagtttctc
    21721 agggccggat taagcgtcgg tctggatatc ggcgtagaag tcattcaggt cacgttctcc
    21781 gttaccatca tcaataccag catcacgtcg cagcctgtca gcctcgagag ataccttatc
    21841 agtagccgcc aaacgataat cagtgtcggc gtgtattttg ctaacggtcg ccagcgttcc
    21901 aacgatggat tcaatgcgca cggtgttacg catcatcgcc ttttcggcag cgctgatgtt
    21961 atccatcaga attttgcgct gctgctcttc ctccgcatcc tccagcaggg tgaaccagcg
    22021 accaatgttc tcggcggcca tcaggttatt cgcccgcagc cgaaagagct catcttcaag
    22081 cgtcagcgct ctggcatcct caacaacttc atctttcagt agaaggcgcc gggcgtaacc
    22141 gccatgtttc agtgcatact gattaccagg ctgaaaagga ggatgattag tgacaacctt
    22201 tttgcgtacc gcttcgggtt tcgtatctgc gggaggtccg gattctggcc gcgaatgctt
    22261 ttgcactgcg ccggagctgg caggcctcct cgtggtacgc accgtgtttt tttgcgtacc
    22321 atttttgcgt acctgcgtaa tatttttgcg tacccactcc agcttctttg ctttcttcct
    22381 tatcgcccct tccgttacgc cgtacagcgc ccctatgtcg cgaaggctca taattccggc
    22441 ccggtatgcc gtctcgatgg cctcccagtc cggttttgcc atgttgctgt cctatggtta
    22501 aagccattaa aaaagccacc cgaaggtggc atttgtgatg gcaataaaaa ccgcccggag
    22561 gcggcttgtt atcaattact taatagctgt tcgatattag atgggatcgg gacaccaggc
    22621 tctactttta gtttgtttag cctttcgaca atagacagtt tctccgcccc actcgctgct
    22681 tggtagtagg gtcttacccc ttcaatgata tcattagctg taactgaaga accaacgcca
    22741 gcgcctggct cgtttttatt caaagagctg tgaataattt gctcaatagc ctgattcata
    22801 gttattaccc aaaatgagtg gttacatacc acaacttgta tatatgtcca ccacaggcct
    22861 ttatcaagcc cacccgtaga taggctttgt aatggctact tcactgtttc gatggtcgag
    22921 ccgtgagagt tcatcacgta aacctggtcg ccaggataga tgaactggta acggcagcca
    22981 tcacccgcgc cggggaaatt ttcactcgga tattcctcaa taatgatggc aatagcatca
    23041 gtatccagca catcagtacg gtcactaata accagttctt cctcctgcag cgctttggtc
    23101 atttctggat cttcatagat agccgggagc cagtatgcga agtccgggca ggctgagtta
    23161 tgagtaagtt ttaaagtatc tgcgaacgtt tcagaaccgg ccctggctat cgagatggat
    23221 ggctgctcac aaatatgcgt aacaccgttg atgatggttt taactgtaaa catagtattt
    23281 ccttcttcgt cttcttgtta caacaaaaag ccccgctagt gcggagctat gggattgttg
    23341 gttgactctc tcaccgagtt gtaaatgcgc tcacacgtca ttcctgcgcg gtagctttcg
    23401 tcagatcgct cagcataata ttgagcttct tctgcaaggc ttccgaacat gtcggcgagc
    23461 actgtggcgt cggctccggc tgttttgctt ctgacggcag cggcaagatt tgcggtgtgc
    23521 tttgcggcgt ccaggcgggt ggcaagtttt tttgcttcgg tacgcagctg gctaacagtg
    23581 gcagacaggc cagcagcagt ggcagcagat ttagcggctt gcgcttgtgc atctttcaca
    23641 gcctcatcac gggcaataat gcggccctgt tcaataatac gggcggcggt ctgggcgttg
    23701 acttcctgag aggattcagc gctgtcgcga tctgcccatt ttttttgcca gcccctgtca
    23761 ctccagacat taccggcgat aaacgcacca gccatcagca aaataaacgc cagctgcaac
    23821 cagtatcttt tcagaagagc agataacaga ttcataccag caccgatttt gctttctcaa
    23881 agcgctctcg ccgatcgccg aagccgttct gccctccgtt gatgatctgc gtaacacgta
    23941 ccaggtcgcc ggaatatttc agacaccctt tagtcacaaa aaaccacgct gcggatcggg
    24001 cggcatgacg ttccagttca agctgtcccg gattcgccac cagatccagt ttcagggcaa
    24061 cgccacatct ggtgtaattc tccagcccgg taatctggat aagcccacgc ccgcgatact
    24121 tccagccatc tccggcgtct ttgttaccca tgcggccacc gtaaaccaga ttggctattt
    24181 gtggctggtg ggcaacctgg cgaccatcaa tacgccccag catttcgcac tgatacggcg
    24241 tcaggcgttt accaaacgtc ttcttcagcg cctccactga ataattgaag ctttccttca
    24301 gaacagtaaa tcctgctgat tcatgtcccg cttgtgcaat aaacatggcc tgatccagtg
    24361 gcgcagtgat accgaattcg ctcattgccg ccgtaatata cggataccag cgcgcagaaa
    24421 gcccggcgct aataccagcc gcctgctgaa attgttgttg attcatcagt gcctcagagc
    24481 atcaaccaga cgcgccacat taccgcgagc ccacagcaca gcggcgcaga taaggatatt
    24541 caccatcacc accagccagt gggatgattc atataaacca aaaacaaacc ggaaagggac
    24601 actggcatac accagcacca tgacataggc cagtaacgaa atcagggggc ggtgtgtcgc
    24661 atcaccgcgt cggtaaaaca tcagaacgat gactattacc ccacaaatta cggcattcag
    24721 aactgcagaa gggtcatttg ctaccatctg atccccctcc cctgatacga gagagaatac
    24781 tgaacagagt gttcagatcc tgactgttga gaaaagtgag aaactttata cacattgcag
    24841 aaataattac tgcgccaagt gcatccagtg gtttttcata atgcgttatt gccgcaagct
    24901 tagtacctat cagcccggcg ccaagcactc ccacaataaa tgacgtgata aaataagcga
    24961 ccagcctgat gcgtccgatg ttggttgccg tggcgacata aaataccgag ccggcaaaag
    25021 cgccgaatac cacaccataa tcggttccgg ttgccagacc gaatacactg gcccccatta
    25081 atccaccagc caacactgtc gcactggata caggttcgga cattcatccc cctctggttg
    25141 tgtgggtcct ctcagttatg aggggaaata ataaatatcc tccggcatag ccggaggata
    25201 tttattcata aagaacacaa ttaagaataa taccgattta attaaaataa cttgatctca
    25261 cagttgaaga atgaataata gcgagccctg ccaaggcagg gcatagaaat aaccaacgag
    25321 aagaaatagg taggaactaa tgaaaaacac cgctctgggt aagttcattt ttatcgtcgg
    25381 caccgcgtta ctgctcggtg gctgtagtgg catggtcatg cctccctatg ccacccacgg
    25441 tacatcggtc ggaatcattg cgccggcggg aggctatagc gagtggcaca cggatagccg
    25501 caaccacacc acaggagaca gtcacagcca gtcacaggga aactgcaccc aaagtgaaga
    25561 tagccagctc agcgaaaatg gtctcacacg gacacaccaa agcaactgta acacccgtag
    25621 tcaaacccac agcagtagca ccagcaaaac ccgctccagc agcgtcggtt tcagcgtcgg
    25681 ggggcctgtt ggtgctagca tagggttgat caagcagatg gagtcgatga accgtgcgcc
    25741 agccaacgat atgagtagta atgagatgtt caagaatttc ggtttctagc acataacgcc
    25801 acctggtacc gttgtggtgt ctggcccggc ggctatctgt aacgactcac aatcgaaaaa
    25861 agtcagactc gcaatcagcg caaattttgg ctcacaataa ctgcaactga aatcggacgt
    25921 ggactcacgc taagtgagag cgaaatctga cgctcagagc caaatgagaa gttttttcca
    25981 ttggcagtaa ttgtgagcca gcaaaaatag attgtgagtc cattgaatgg ggatcgttgt
    26041 gcattttcat aagcctcacc tccgatagct cggatggcgc agtgtgaagt aggaaggccg
    26101 cccggtggat caacgacaaa gctcagaggg attattccgg acggcacaaa cagaaaagcc
    26161 ccggcaatca ccgaggctta aattgttgcc ggttaccgct ccggcgcgat cagcaaaagc
    26221 tatcgcggta tcagattgtg gtcctgcccg tgtgagcttt gcggtcggct ggaacatgta
    26281 gactccgcat cactccccgc actttgtctt attggcgtcg ggaatccata aaagaaaacc
    26341 ccgccgaggc gaggttctta attcttgtaa cgtcacaggc gtaataaccc atcgttggaa
    26401 tcaggttagc cattttccgt taattttgca atagctaaat tattttggtc atcgagtcac
    26461 gtttcccaga accttttctg catacgactc ctcaatatgg caatgctcca ccagtcgatc
    26521 gaaaaacagt ttatagttgt accgccatac catttccgtt actcctagtg ctttaaaaat
    26581 ctcggtatct ttgagacgtg ggtagcctct tcccttgcat cttgggcatt ttttataaac
    26641 cggcacgccc tgcaactcag attttttctt atcgagaatt tctccgcgtc cccggcaacg
    26701 acattcattt ttcacctggc ctttgccatc acacgcctta cacactacgc gcacctgctc
    26761 acgaactgat ttccacacct cccagtcgga cggagaaata cctttcgtat cttttaccca
    26821 ttttggtggc ttaccatccg ggtaagtaac cttgttcgtg aaaacctcag catcaattaa
    26881 tttagcacca tgacagctac tgcacgtcac caagctggcc gcactgaggg aataatcgcg
    26941 aaatacataa cgcgccatag tgtcgagaaa ttttgagcgc ttaccctttt ccattttccg
    27001 taatgcccca tgccgttctg cacgctgctc tgctaattgc ctgatgtagg cgatgatatt
    27061 ttcagaagat aaaaccccgg cttttgccag atacaattca atacccactg cggcttttgc
    27121 agtaagtagc ccgagagatg ccattacgtc agtaatagtc agcgtatcag acgttattcc
    27181 gcatggtact gcgccgggca tcatggattt aggtgaaaaa tatttcggta aggactcaag
    27241 attcatttcg atgctcccgt tttgcttcaa tgcggacgta attacgaaga atgcggtatg
    27301 ccacaggaaa agatccccgg tatcgataaa ttcggagacg caaccagcgc atgcggagta
    27361 tctcgatcag ttctggtttc atgcggcctc cagctttttt agcgcacgca gatccgacag
    27421 tgccgcgagc ctgatttcct tcagctcctc gaccgtccag cggtgcgggg tgttattgtt
    27481 ctcgagtgcc agcaccgccg cctcaccgta acgctcaacc agcgcggcac gatatgcttc
    27541 gatgttccct gatttgtaga cgttgcagac atcacactga agatggatgt tgaagcgagt
    27601 gaagcgcaga tgcccggcgg cggccgtact cctgtaatgg cctgcatgcc atgcgaatgc
    27661 cgtcttcgtt ccacaggaga tgcaaccgag tccttctgcc agttcggttt cgcggcaaat
    27721 gtcatttacg gcgcgctgcg tcaagtcaat ccagtgtttc agcggcttaa ccgcggcttt
    27781 ccgctggcgc caggcggcgc gttctttttt ctcagcggcg cgctgaaggg attgcgcctt
    27841 acgttgcgcg gcttcgcgag cttttctggt ctgttctttg ccgacggtgc tggcgcactg
    27901 gtacgagcaa acgatctgcc cctctcgtat cgggtgaaac cactggcggc attctttgtt
    27961 tgcgcactta cggcgcggta atttagccat gttcaccccc agaccttttg gcgtaaggat
    28021 tttggcgtcc gcacccggtg tgcatattct ggtaatttcg cgctgacagt ccaggtaatg
    28081 aagtcagggt tcaggctctt ttctgtcctt acgccccgct tctgataatc cgatatcagc
    28141 gtgtcggcct gctcggttgt gcagtcgtga tgatggaacc aggagtattt catcgccatc
    28201 accccgcaaa gctcatgagc tgggcggcgg cgttctccgc ctcgcgctga gtacgaaatg
    28261 tacgtgataa aatccaccgc cagagcacat caagcgcgga tttatacaac tgctgaaatt
    28321 cgacctcatc catgctggaa aaagcgatgc tgcggggatg tttgcgaagg gtgccgtccg
    28381 gtaactggat ggcgtcatag tgaccagcct caaccgtcac ccatgcgcgg tatgcatcga
    28441 aagatttaca gaggctaatt ccgtttgtta cccggcggtt tgcaatctgt tccagatact
    28501 gttcagccgc atccagtaat gcgctttcat tcccgccata tgcagcgaga aactttgcat
    28561 aaccgtttac cagtttgcgc tcattggcag aaatggcgcc gccggtgggt tcccagtatt
    28621 caaacccaag attaagcaac gcgaaaaagc ggcgatggaa tgcaggattc ctcacctgac
    28681 ggaactcagc caccagcacg gcgccgagtt tgatttttga ttgcagaata tcactggtct
    28741 ccggcgttgc ggggatcaga attccagatg actgcttgat gagttgtaat tcgtgcgcca
    28801 tggcgttctc cgtggcgcag caggtgcagg ttgttcaggc ctacatttga agtgtatcaa
    28861 agcaacgggt aattcgatag cctgcctttt ctaacatttg cgtaaataat gttggagttc
    28921 caactatgtc atcagggtga aggggaacaa aagatatctc gtcaccacga cgatacatca
    28981 gggcgcgtcc gctatccgga atactaccga accttgccac tacacaatga tcgtaacaac
    29041 gtataaccgc ataccctgat tctggtaagt cttctaacat gtaacccccc gtcacactga
    29101 ctttatttct ggaaacgtct gcgactccac gatgcttaat atgcataaaa ccagtcgtca
    29161 gcgctttccc acgtttcctg cagaatgctc tgtatacgtt ttttatcgcc atcagcagca
    29221 ccgacgatac tcagaccatc ctgactgcct cgacggatgg ttaagttgca gttttcatac
    29281 tgattctgga gacgggtaat taattctttt tcaagtgcag gcacggcacc ttccggaagc
    29341 tgttttgtcc ggctgataac aagttcaatt ctcataattc cctctacatt taactactgt
    29401 atataaacac agtatacctg ttagaaagaa tattcaagag gtgaatagca ctttttgcaa
    29461 aagccatgcc attgtatagg aagagttttt cctagtattc ggaatttact aaatcagtta
    29521 ggcaaaggct gaaagcgaaa aaaaacccgc cgtagcgggt tattcattcg atttgattcg
    29581 gatgtaacgt gaggtcgcca cgagagcctg aatcatatta ccgccagttt cgcataacgt
    29641 tctggaatca tactcgcgtg accagtggca taaccaattt tccaggtcat ccactgcgta
    29701 atctttacga gccaaaccct ctgcgatggt tacaacttca tcactaggtg ctgtaagctc
    29761 atatccgttc agcaacagga atacgtaacc tgccatcata gcggtgcgtt tgtttgcgtt
    29821 tgcgaatgga tgattctgga ttaggctttc aattagaaca gcagacagac gaaacatatc
    29881 gtctgtctgc tcataatatc gaatggtgct tggccgggac tgggaagaac tgaggttgtt
    29941 cggattcagt acgcctatcg gttcatttgg cgtctgaatc tcgatcagag acctgttgat
    30001 gtaaacgata tcttcaatgg aaagataatt gactccttca acatactcta tcgccatccg
    30061 tttttactca gacctttgaa agttcttcca tcgccttctc gtaacgagca aacccaaact
    30121 caaaggcgtt tttaacttga ccagtatgtg aacatgcttt gctgatcgct gcacgaggtt
    30181 tcgccaccat ggatttgtca cgaggcggaa tgtacaagcg atctgccttt tttaatgcgt
    30241 gacccatgat tatcaccctc atgcacgttt ggcagtgctt tctcaaattg taggatgtaa
    30301 acacatccaa agaatttatg atcactttaa gtggttgagg acaatttaat accattcgtc
    30361 atatttgagc aatgggcctg cgtctgaaga tagaagcatg ttcgacgaaa atctcaatgg
    30421 ccactttgca agttaacgac attttcgcag aagttacccc tcaggtaata gtaaactatt
    30481 gtcacgatct caggagatag gctggtcctg tgagtcgatt aaagtggaca caaagccaat
    30541 aaatagcact ttttgcacaa aaatcatatc ctggttggaa tgcacaacgc ccaacattgc
    30601 tgtagtattt cgccccctct gaatgtagcg ctcagatttt aatcgaccca atcccgccct
    30661 gcttcaacat caagccccgc atatgcgagg cttgttgggc taacccgccg cagcgggtta
    30721 tgacgcaaca cttcatgccg gagttttccg atccgtcttg ttgtgaacct cccagagact
    30781 aatgccgcaa ctgaacacaa actcagccag ataatttaaa ccggaccatt cccggatgcc
    30841 gccgcgcgcc gcttccacaa atacagcgat atcctgatca cgccacactc caaacaggcg
    30901 ccagccgcca ctgtcagtct taacggctgc tatacgcgtc agaacaccag tctggtacag
    30961 gtcagtgaac gcaggtttct tcctggttat tattcgcata tctacaaacc taagaaatgt
    31021 tgattacaaa tcactgattc gtattttttg attttgcact aatgccgatc acaggaccgg
    31081 catataggtg tttcacgatt tacctccgtt gagcatggca gcgcgacaag cgttccagat
    31141 ttcttgcgca tcgtcgtcgt tgaaaagcgc atcagaatgt gaagccatca ggtcgcgtat
    31201 ttcttccgga cattcttccg gcactaccgg cactggctgc tctttgatat gcagtcgtgg
    31261 ctcgccgtct ttcggttcag gccattcgcg cttcttgttc accgccagct tttccaccat
    31321 cgccagggca atctgctcgt cagtaatacc agcgcggcgt tgtgcatccc ataacaggaa
    31381 ttgcatatca gcccattcgc tcaggtcgcc aagttctgcg gcagtttcca atgcttcttt
    31441 tgagaggtgc ttcagtggac cgatggggcc aacatcgccg aatgtggcat cagaccagtc
    31501 agcatgttca tggcgaactt gttctcgttc cagcgatgcc agcgcacgct tcagcacaat
    31561 aagaattttg gcgtcgtcat cgctcaggcc aaacggaata tcatcgcgag tgttttcaaa
    31621 ttcagcgatg gtttgctgta gccattcttt ggtaatagtg gtcatgggtt agtccttcac
    31681 aaaaataatc cagtgggttt tatcgttctt gccggtgcgc tggccaataa ttggtttcac
    31741 gtcagtaagc gccaaaatct ggctaaccgg aatctgcgtt tcgttccatt tgaaaatgag
    31801 aacgccgtgt gccctcagca cccgaaacgc ctctttgaat ccggcgcgga ggtcagaacg
    31861 ccatgttttt ttgttgagtc tcccgtactt tttgcccatc caggccgttt ggccgacacg
    31921 ttccaggtga ggcggatcaa acaccacgac cggaaacgac gcatcagcga acggtagcgc
    31981 acgaaaatca gcaatgaggt caggactgat gactaggcgg cgaccgtcgc acaatatatg
    32041 ctcctcggcg cggatatcgg cgaatacggc gcgttcatcg cgcttattaa accaaaacat
    32101 gcgcgagccg cagcacatat ccagaataga ttgcgattcc atcacgactc cttaaccttg
    32161 atgccagcgg tgcgtatttc gtgtatcgca ttatcattac cagcacacca accctcggca
    32221 taatcccggc tgaatccggt catgtgcatg acttctccaa cgctgagttt tgacaggttg
    32281 accttccgcg cctccagttc tgccacccgg cgagcctcac gggttgcaat tcccgcgtat
    32341 tcaatcaggc gttggtccag ttcggctatg aggcgttctg ctgtatccaa atcctcgcct
    32401 aacttctgcg ccatccgaaa ccaattggcg cgctgttcct ctttggtttc cagctcatcc
    32461 agcagcgcca gcatggtggc ggggttggct gcggcgataa attccgcgtc acgtttctca
    32521 acagtatggg ccaacgtcac ttcttcaccg caaagagaaa atggcgttac cgtgatgcca
    32581 ttgaacagtg atgaggtgcg gcgccaattc cccggcgtag ccctctcagc cacttcacga
    32641 agcgcccgtt tgtcgatgtt gctcattggg ctcccccctt gttgatgctc attttggatg
    32701 ctccataaac ctgcattacc gggcttttct ccagcaccgg cagcgctgaa aatcccgtta
    32761 cctgactact gctgtatcgc ctgaggtcat aatcaatcac cgcacgctgg tctcggaaaa
    32821 tgccgcagcg gccatgacga atgaagccgc ctcgctccag cgcgatacgc agatatttct
    32881 ccgccgtggt tcggtgcacg ccaaaaatcg caacgacgtc gttcgtcgtg atgcgcccct
    32941 gctctttcac cagaccgata atccgctcaa gaataatcat ccgttcgctg tgtgttttag
    33001 gtcgggccat ttttaacccc ttatttcaca atccggaggt ggctaacgtt tttccggtag
    33061 ctttcccagt caaaattcac ccacatccct ccgtccatct ggaggcgatc gataaccctc
    33121 gcgcccagtg aatccaacag cccctcgtgg ttaagattcg tcagaacgcc aacaggtcgc
    33181 atcgatgaga gacggcgatc gataacctga ttgagaatga ccttctcacc actgctcccg
    33241 cgctgaatac cgacttcatc cagtaccagc aggtcaactt tgcaaaggtc atcaagcagg
    33301 gacgcttctg attgcccacc gtcgtagcac tcacgaaccc tgagcatcag gtcaggaatg
    33361 gttaccacca gaacgctatg accgccggcc agcagatgat ttccgattgc cgccgcaaga
    33421 tggtttttcc cggttcccgg accaccgctg aacacaaagc tcgcaaatcc actaccgaag
    33481 ttctgggcat aactttttgc catcgtgtac gcttttcgct gcccctcccc gcttacttcg
    33541 tagttagcaa acgtacagct acgatggaga tcctgaatgc cagatcgccc gaaaatcttc
    33601 tcggtgcggg atttctgatt catcctgtca agctcttcac tgcgtttacg cccttcggct
    33661 tcctgccatg cccgccactc atcagcagtc gagaatttcg gctgcacact ggctgggata
    33721 attcttttca ggcgatcaag cgcactgcca gtaccgatta cgtttttcat cgttaccccc
    33781 tgaatccggt aggaatggtt ttgtctggcg cagaaatgtg gttcacatct ctgccagctc
    33841 ttcggtcgtt gagagcgaac ttcggtttga atagtccctg gtagccgttg gcaatgcttg
    33901 tgttgatgac gtttaccgga tcgtggcctt catccaggca ctccttcaga agcctgaaag
    33961 cttttgttac cgtcagttcg gtttttatgg gctttccgga ttgctggcgg tatgtgaccc
    34021 attcgttcca cgacgcagca ttcagccatt cgggaacagg aatactcaac ggatcaaact
    34081 tcacttttcc cttaggggga ttaaaggggg ttagatcttt tatatttgtc tttggaataa
    34141 tgtctttggt gttccctgtt ttcggggatg cccttccctc ttttcgggga taactatccc
    34201 cgttttcagg gatggctgaa tggggtaaaa cgctatccct gttttcaggg ataactatcc
    34261 ccgttttcgg ggatgccctt cccccttttc gggtataact atccctggtt tcgggtacag
    34321 aaataatcca tgtggcaatt tcatcatcag gaaaagacac cggacatttt gagcaatgtg
    34381 gcttggaata agcccattta tccaggtttg tattaatccc tatgtatctt gtttgaccaa
    34441 tacggcgcag gataatgatg ttacgatagg caagactcag caccgcttcg gatacatgct
    34501 ttaccttcag tgttgtctta tctgcaatga ggctgttggc aatacgatct gattttttcg
    34561 accagccata agtcagccgg ataatcgcat tcaaaacacg gaactcacgc cccgatagtt
    34621 caacgataca caaggcgtcc tggatctgat tagctaaacg taaatagcca ttttccagat
    34681 cagccatacg gcactcctgt tgcgtcggta tcggcgcagg gaatttgtat atttcagcgg
    34741 tatttgacat actcatctcc gcaattacct accgtttttg caccagaaag ccgttggtga
    34801 cccctcaccg cggctttcgc ctttttggtt gctgtcattt tcagtcccac cccagcgcat
    34861 ccggcctggc tcgttcagcc tttagcccgg catcagcgag aatctctacg gctgtgagat
    34921 agtttctgga taccagtacc gcttccggtg gcgcggcctg aatcccaaga aaagccagct
    34981 ctttcgccat gttgcagaaa tatccctcag ctttacgcct gctgactgtc gactcgctga
    35041 tgcccatatg ctcggcgtat gatttctgcc ctactgatgc aagccggttg agcaggacac
    35101 tctctatctc aatcgggttg atttctggtg ggtctaactt tcgtgcaatt gcgttctcca
    35161 tgggtaaata tcctctatgg ttatttggct gatgcctctt ggcttggtaa gccatcggtt
    35221 gggtttgggt agagatcagg acgcagttcg tgtggggtga ctttccagtc aatagctctt
    35281 gccactcgaa ctacaagttc gccgggaact ttgtttttaa accagccgtt aacggtctga
    35341 gcacggcgac caagtcggcg tcccaaccca gcctggctac acacggaaag gatcttgcgt
    35401 tgaacagtta ctttcattgg tcggtctcat tgagtgaaga tacaaccaat tattcaaatt
    35461 taatcgatac tgtcaaatta tttcgataga catacctaca gaaaaaatct gtataatgaa
    35521 accatgtaat tgtgcgagaa cgaaaaatga actttggaga gcgtttacaa agagtgctta
    35581 atgagactgg gatcacccaa tctgagttag gtcgtagagt cggcgctacc tctcaatcag
    35641 ttaatggttg gtgtcagtcc ggcattcttc cccgaaaaga tatcttagag ttgttaccta
    35701 aggccacggg taagccgttg tattggttct tcatggagga tgatgatgaa tcggatgtgc
    35761 ctgaacgtct aacacaaggt ggtccaacag atctcaatga ccgacaaaag cggctcttag
    35821 aaatatttga tcagctaccg actgttgaac aagaccgttt tattgagctg gcaggcacca
    35881 gacttcaaga actagacgat ttcatggctg aataccaaag acgcagaaaa atcgagcctc
    35941 cttctcgcta aaccagcttt aaaactacta accgccttaa ctggcggttt ttttatgtca
    36001 ttaattcacc cacatctcgc tttcttaatc ttccctgtaa aattaatcat caaatttaat
    36061 tgacatgtat cgattgaatc gataatactt aacctatcaa ccgcagcaac gagtcatcaa
    36121 ggcaggacgc ccacgaagta gccgcccggg gcatacgaag accgggatga gatggcaagg
    36181 ttaacgcgca gcaggtgata aacgttccgc tggccggcga taaggcaaac gagggtgaga
    36241 tgactaatta cggcacaaca acattaccaa gaaccagcgt tgtaccggga atgctggtta
    36301 agtaccaggg gcgcacatac cgcgcatctg caaacgtagg aaaagggttg tacttgttta
    36361 cccttttcga acgcctgcgg acaaccaacg acgagatcga ggtttacctc aaccaacacg
    36421 gcaaacctgc aacccattag caggaaaaac cagcaaaacg aaatactgca cagattctgg
    36481 cagaccacat ggtgtcgggg attctgcaaa ccaaattcag gagttcagcc atgaacgcat
    36541 atctcactta cgaccggatc gaggctcagg actggacccg gcattaccag caaatcgcca
    36601 gagaagagaa agagtcagaa cttgctgacg atctggagaa aggactgtcg cttcacatgc
    36661 tggagtcgct gtgtatggac gagctaccac gccacggcgc caacaaaaaa gcgatcagcc
    36721 gggcatttga tgacgatgtc gaattccagg agcgcgcgtc ggagtttgtg cggtacatgg
    36781 ccgagacgtt ttcccggcat caaattgata ttgaatcaga ggaataagac aaatgagcac
    36841 agcactcgca acactggcag gaaaactggc tgaacgtgta ggaatggatt ctgtagatcc
    36901 gcaggaactg atcactacat tgcgccagac agcgtttaaa ggtgatgcca gtgatgcgca
    36961 gtttattgcg ttactgatag tcgccaacca gtacggtctt aatccgtgga cgaaagaaat
    37021 ttacgccttt cctgataagc agaacgggat cgtccctgtg gtgggcgttg atggctggtc
    37081 ccgtatcatc aacgaaaacc agcagtttga cggtatggat tttgagcagg ataacgaatc
    37141 atgtacatgc aggatttacc gtaaggaccg taaccatccg atctgcgtta ccgaatggat
    37201 ggatgaatgt cgccgggaac cattcaaaac ccgtgatggt cgtgagatta ctggaccgtg
    37261 gcagtcacat cccaaacgga tgttgcgaca caaagcaatg atccagtgcg cccgtcttgc
    37321 cttcggtttc gcaggtatct acgacaagga tgaggccgaa cgcattgtcg aaaataccac
    37381 gtataccaca gatcgccagc cggaacgcga catcactccg gttagcgatg aaaccatgcg
    37441 ggaaattaat gatctgctga tcaccctgaa taaaacatgg gatgacgatc tgctgccgct
    37501 ctgctcccaa atcttccgtc gcgatattgg tgcatcgtca gatcttacgc aaatcgaagc
    37561 agtgaaagcc ctcggattcc tgaagcagaa agcagcagaa cagaaggtgg aagcatgaca
    37621 ccagaaatta tcctggctcg tacaggtatt gacgttagca acatcgagca aggtgatgac
    37681 gcgtggcacc gtctacgcct cggtgtcatc actgcttccg aagttcacaa cgtcatttcc
    37741 aggccaaagt cgggcaagaa gtggactgat atgaagatgt cctactttct cacccttctt
    37801 gccgaagttt gcaccggcgt ggcaccggaa gttaacgcca gggcgctggc ctgggggaaa
    37861 cagtatgaag atgatgcccg caccctgttt gagttcacca ctgacgtgaa agtcaccggg
    37921 tcgccgatcc ttttccgtga cgaggacatg cgtaccgcct gttctcctga cggcctgtgc
    37981 agtgatggcc gcggtcttga gttgaaatgc cctttcacct ctcgcgactt tatgaaattc
    38041 aggcttggcg gcttcgaggc tatcaaatcc gcctatatgg cccaggtgca attcagcatg
    38101 tgggtaaccg ggatagatgc ctggtatttc gcgaattatg acccgcgcat gaagcgagaa
    38161 ggcattcacc acgtggttgt tgagcgcgac gacaaataca tgtccctctt caatgaaatg
    38221 gtaccggaat ttatcgaaaa gatggacgaa gcgctaaagg agattggctt cacgttcggg
    38281 gagcagtggc gatgacgcac gcacaggacg aaatcagggt tggcgcgatg cgccatccca
    38341 tgttgaagaa ttaaatgtta gaggacggaa gtatgagcaa aattggtgac tatttctttg
    38401 aattcccggc atcaagaggc ttacagggaa atacggttgt gttgatgatg acagtcccag
    38461 cgcgcgcgct aactcgcgtt ctggcatcag ataaccacgg caatacgctt gagcgttctc
    38521 agcgagaact caatccagcg cgtgcgaaga agttttatga atacctgcga acagcttacg
    38581 agaaaaaaga gccgttcatc atcccgccgc tggttggaaa ctgcgactca ttcattgagt
    38641 tcgaagagtt tggcaatacg aatgtgggtg tcgcgcgatt cccaatggat gcggaaatta
    38701 aactgtttga cggtcagcat cgcgccgcag gcattgcaga gttctgccgc acttacggag
    38761 agcctattca catcccaatg atgctgacac accaactgcc gctcaaaacg cgccagcagt
    38821 tcttttccga catcaacaac aacgtatcga agccatcagc ggccatcaat atggcctata
    38881 acggtaggga taaaattgct caggatatgg tttcgttttt gtcatcccat gccatgttct
    38941 cagaaataac agactttgaa cacaacgtgg ttccggcgaa aagcgatctc tggattagct
    39001 tcaaacccct gagtgatgca actgcaaaat tctctggtaa tggggatgag cttgctacta
    39061 gtgacatcta tgacatttgg gaggcatggc tcaagctaac agccatcaag ggaattaggc
    39121 atggttgtac gcctgttgaa tataagcggg attacatcca gttccacgcg gtgatgatca
    39181 atgcgtttgg ctacgcaatg caggaactac tacggcatcg ccctgcacac atcattgttc
    39241 agatgattga ggagttagta aataattcca ctatgagtga gctggagaat ttcttcctca
    39301 tttcatcctg gtccggtgtc tgcgccagca ctgaaaaaga tagagcgaca gttattgcca
    39361 gcgttgcttc acaaaaagct gcttcggtga gactaatcca agctattacg acaaagagct
    39421 ttgaggtcgc agcatgagat acggctctgt ttgcagtgga actgcggcga tgcccataga
    39481 ggaaccggcg ctgcgcacct ggcgccgccc gttcctgaaa tgggcaggcg gtaaatattc
    39541 gctgctgccg gaactggatc gtcttatccc ggcaggtaaa cgactgatag agccatttgt
    39601 gggcggcgga tcggtgtttc ttaactcaga caagcacgaa cgcttccttc tggctgacgt
    39661 caacgctgac ctgattaacc tgtaccagat gctggccgta gtgcctgatt cggtaatcgc
    39721 agaggctatg aaagctttca gacatctgaa tgatgccgaa aactacacag taattcgtga
    39781 agcattcaac gcccagaaac tgaatgcgac agaacgagcg gccgcattcc tttacctcaa
    39841 caggcactgc tttaacggtc tgatgcgtta caaccttgac ggttttttca atgttggatg
    39901 gggaaagtat aaagccccat atttcccgga agaagagatc agggcattca ggcagaagtc
    39961 tcacgcgtgc gtatttatga ctgcgggttt cgaacgtact ctcaggctgg cgggtgatgg
    40021 tgatgtcgtt tactgcgatc cgccatacga gccaatgccc ggcaccgctg gcttcactaa
    40081 ctacgcctcc ggtgggttct catgggatag ccaggtagcg cttgctgaaa gctgtgtggc
    40141 agcccatcag cgtggcgcaa aggtgtttat cagtaattct accgcaccac gcgttattga
    40201 actttacgag aggcacggct tcactctgca ccgggtcaat gcccgcagat caatatcgag
    40261 taaaggcagt acccgagaaa cagcgaacga tatcgtcgcc tcactgggga tttagtgatg
    40321 atgaaactta ttaacagaag taagcaatca ccagtcggtc gtcgcgcatg tgatattgca
    40381 ctggctgcgc atcatgagaa gttcggcgat tacggcagac aaaagcacgt taccaattac
    40441 accgttgtag tggatggcgt aaaggttcct gtcgaagtag ttaaccgggc caccagctac
    40501 gtagccaccg caatgatcgg cgtccggaaa cttagaaatc tgccagcaca ggcaaactga
    40561 atattagcga tggcccgctg cggggccact ggagaaaacg atgagcaaca ttatccaact
    40621 gacgccaaac aagtgggtta gcgaaaaagt tctgattgcg gttaccgggc ttaagcccgg
    40681 aaccattacc cgcgccagaa aagaatcctg gatgctgggc cgcgagtacc tgcacatttc
    40741 accagacgga aatccgaagc cttcgagcga atgcatatac aacagagaag ccgttgatca
    40801 gtggatcgag gcgcagaaaa aaaatcaacc aggtgcgaag acaacatgaa aagcagtaca
    40861 ctcgtcaatg ctcctggacg tcaggaggga ttaatggcta atgcatcata cccgacaggc
    40921 gtcgaaaacc acggcggttc gctccgcatc tggtttctgt ataaaggtaa acgtgtcagg
    40981 gaaaaccttg gtatccctga cactgcaaaa aatcgcaaga tagctggcga actgcgttct
    41041 tcggtttgtt ttgcgataag gatggggaat tttaactatg tggaaaaatt cccaaactca
    41101 acgaaccttg cccggttcgg tcaggataga aaggaaatta ctgtgctgga gcttaccgaa
    41161 agatggtccg agctgaagag aatggagatc agctctaata ccatgagtag gtacgaatct
    41221 atcataaaaa acatgcttcc actcatcggc gaaaacaaaa tggtttctgc ggtgactact
    41281 gaggatttgc tgtatgtcag gaaggagttg ctgacgggct ttcaggtaat gaagaaggat
    41341 caccggactc aggttaaagg ccggaaatcg tccacagtga ataattacat gatgctgatg
    41401 gccgagatct tccagtttgg aacagataac ggctatgcaa aggaaaaccc gtttagcgga
    41461 attaaccgtc tcaagaaagc gaaaggggaa ccagatccac tcacgacaga cgagttcatc
    41521 aagtttatcc aggcatgcgg ccaccagcag atgagaaatc tctggtcact ggcagtctat
    41581 accggaatga ggcatgggga gttgtgcggt ctggcctggg aagatatcga tctgcatgcc
    41641 gggacgatca ttgtgaagcg caaccttacc cagacggatg agttcaccct gccaaaaacc
    41701 gacgcaggta ctgacagggt gatatatctc attcaaccag ctattgatgc cctgaggaat
    41761 caggcccagt tgacacgcct tggccggcag tttgaggttg aagtgaagtt gcgggaatat
    41821 ggacaatctg tcattcagcc ctgcacgttc gtattcagcc ctcaatgcgt caaacgtgga
    41881 cctcgcacag gatatcacta cgcggttaat tccattaata aaatttgggc cccgataatc
    41941 aagcgtgccg gcattcgtta ccgtaacgcg tatcagtcac gacataccta tgcatgctgg
    42001 tcattatcag ctggtgctaa cccaaacttt atagcaacgc agatggggca taccgatgca
    42061 cagatggttt acaaggtgta tggaaagtgg atgtcagaga agagcgcaga acaggtttct
    42121 ctgctcaacc aggcactttc ccgctatgcc ccatcactgc cccaaagcat ggtagcagcg
    42181 cagtagaaat ccttaaattc aaggggttag cagtcgcatc gctacatttt tataacatgg
    42241 ggcacgaaat gcgctcgacc ctaaagacag cttatggtgt gatcggggtt caataaatcg
    42301 ctaaacaagg tatactccag cggttttctt agttgtttat tgtactaaac actcccgtga
    42361 gaggacgcaa cagcgcacct atgacacaat tcgcttctcc tgttctgcac tcgttgctgg
    42421 atacagatgc ttataagttg catatgcagc aagccgtttt tcaccactac tatgatgtgc
    42481 aggtagcggc tgagtttcgt tgccgtggcg acgacctgct gggtatttat gccgatgcta
    42541 ttcgcgagca ggtggacgcg atgcagcacc tgcgcctcca ggaggacgag ttccagtggc
    42601 tctccggcct gccctttttt aaaccggatt atctgaactg gttacgcgag tttcgctata
    42661 acccagctca agtctgtgtc accaacgata acggcaagct gaatattcgc ttaaccggct
    42721 cgtggcgtga agtcattatg tgggaagtgc cgctgctggc cgtgatcagt gagctggttc
    42781 atcactaccg ctcgccaaac gcgggcgttg atcaggcgct cgacgcgctg gaaagtaagc
    42841 tggttgattt cactgcgtta accgccaatc tcgatatgtc ccgcttccac ctgatggact
    42901 tcggcacccg ccgccgtttc tctcgtgaag tgcagcaggc gatagttaaa cgtctccagc
    42961 aggagtcatg gttcgtcggc accagcaact atgatctcgc gcgtcgcctg gcgctgacgc
    43021 cgatgggcac tcaggcgcac gaatggttcc aggcgcatca acaaatcaat ccggacctgg
    43081 cgaccagtca gcgtgccgcg ttggccgcct ggcttaacga atatccggac cagcttggta
    43141 tcgcattgac agattgcatt acaatggatg cgtttttacg cgatttcggc attgaattcg
    43201 ccagccgtta tcaggggtta cgccacgact caggagaccc tgtcgcatgg ggcgaaaagg
    43261 cgattgccca ttatgaaaag ctggggattg atccgctgac aaaaacgctg gtcttttcag
    43321 ataaccttga tctgccaaag gcggtcgagc tctatcgcca tttcgcctct cgcgtgcagt
    43381 taagcttcgg catcggtacc cgactgacct gcgatatccc tcaggtaaaa ccgctcaata
    43441 tcgtgattaa gctcgtggaa tgtaacggaa agccggtggc taaactttcc gacagccccg
    43501 gtaaaacgat ctgtcatgat aaagcgtttg tgcgcgcgct gcgtaaagcg ttcgatctcc
    43561 cgcaggtgcg taaagcaagt taaccatgcc tgtgcgaagc gcccggaaag tgggcgcttt
    43621 gttactcttc tgaccatctt acctgttctg gccgcgatgg tgactattct tccccttcac
    43681 tcttcgacat atttacgtgc gtgatttgcg ttgttttttc agaattagtg tcccgctgtg
    43741 tacgcgttct gaataaattg aattcgctaa taaattcttt acgcagcaag aacagagcaa
    43801 ttacgttggg gataaccaga aaaccgacag caatatcagc cattaaccag attaccggga
    43861 tttccatatt aacggcaatc agtggcggca aaaaatatag ccatttaatg atgcgttcta
    43921 gcttatcgcc aaagatatag tttattgaag tgcgaaattt aatatatgaa ccaagataag
    43981 aagtaaacag aatcaacgcc acaccgagac agagaacctg aacaataatc ggatgccatg
    44041 tttcttttaa ggcggcaaag ataatctgaa taccttgata actggcgtct gtccacatac
    44101 cagaagcaag tacagcaaat gcggtaaagt tacaggtaat cattgaaaca aaaaatactt
    44161 ccactgcccc ccacattccc tgacggaaag cataatccac gttggcagta gcatgtactg
    44221 tggccgaggt acccatgccg gcttcgttag tgaatattcc gcgactggct cctttactga
    44281 tggccatcat gatggttgac ccgacaaagc caccggctgc tggcgcaggg gcaaaggcat
    44341 aatagaaaat actttttata acctgtggga tagcctcgat attcaatacc actacaccag
    44401 cggcaccaat gaaataggca atggtgatcg gtggaagtgc aatcgtacag aatttaccaa
    44461 gactggcgag tccttttaaa ataaccaacg cgcctacgat gacaataaat cccccaatga
    44521 cgcttgttgg gatgtcaaac gtatagtgaa tgaccgccgc catcgtatta gtttgcacaa
    44581 aacaggcatc cgtaataacc agaatcatta atgcaaacgc atataatcct gccaggggat
    44641 accatttttt attgagctct ttcttaatat aatgcattgg gccgccataa tattcgccat
    44701 tctcaccttt acttcggtat ttcaccgcca gcgtcacttc aaccattttg gtcatcatac
    44761 ccacgaccgc aatgatccac atccagaaaa ttgccccagg tccgccaacc gcaatagccg
    44821 cagcaacacc tgcgatcgtt cccgcgccta atgagccgga tagcacagtg gcagccacct
    44881 ctattgattt taaggatttt ttagacgctg cctcgccagt agtgttttgt ttattttttc
    44941 cggcaagtgt accaattgta ttacggtaaa tttctttta
//
LOCUS       DAJVKX010000024        44067 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000024 DAJVKX010000000
VERSION     DAJVKX010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 44067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44067
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.024"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(49..1392)
                     /locus_tag="OPY25_001304"
     CDS             complement(49..1392)
                     /locus_tag="OPY25_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCS0926956.1"
                     /translation="MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINA
                     QRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFSALFSHYMSPELSEQLSF
                     ILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
                     IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTS
                     RESIIWFDLHEDEQSLKKKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA"
     gene            complement(1582..2220)
                     /gene="msrA"
                     /locus_tag="OPY25_001305"
     CDS             complement(1582..2220)
                     /gene="msrA"
                     /locus_tag="OPY25_001305"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCS0926957.1"
                     /translation="MSLFDKKHLVTQADALPGRNTPMPIATLHAVNEHSMTNVPAGME
                     IAYFAMGCFWGVERLFWQLPGVYSTAAGYAGGYTPNPTYREVCSGQTGHAEAVRIVYD
                     PAVIRYEQLLQTFWENHDPTQGMQQGNDHGTQYRSAIYPLTPEQNAAAHASRERFQSA
                     MAAAGDHRPITTEIAHATPFYYAEDEHQQYLHKNPYGYCGIGGIGVCLPPDA"
     gene            2433..4166
                     /gene="tamA"
                     /locus_tag="OPY25_001306"
     CDS             2433..4166
                     /gene="tamA"
                     /locus_tag="OPY25_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HCS0926958.1"
                     /translation="MPHIRQLCWVSLLCLSSSAVAANVRLKVEGLSGELEKNVRAQLS
                     TIQSDEVTPDRRFRARVDDAIREGLKALGYYEPTIKFDLLPPPAKGRQVLIARVTPGQ
                     PVLIGGTEVILRGGARTDKDYLALLKTRPAIGTVLNQGDYDNFKKSLTSVSLRKGYFD
                     SEFIKSQLGIALGRHQAFWDIDYDSGERYRFGPVTFEGSQIRDEYLQNLLPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPEFEKSRKTKILPLKGVVSPRTENTIETGVGYST
                     DVGPRVKASWKKPWMNSYGHSLTTSTSISAPEQVLDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTEQDSTTLAVSRYWDLSSGWQRAINLRWSFDHFTQGNVTNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSVDYSNTAWGSDVDFSVLQAQNVWIRTLYDRHRFVMRAN
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSISPKDSDGNLKGASKLATGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWASPVGPVKLDFAVPVGDKDEHG
                     LQFYIGLGPEL"
     gene            4163..7942
                     /gene="tamB"
                     /locus_tag="OPY25_001307"
     CDS             4163..7942
                     /gene="tamB"
                     /locus_tag="OPY25_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HCS0926959.1"
                     /translation="MSLWKKISLGVLIFIVVLLASVAFLVGTTTGLHLVFGAANRWVP
                     GLDIGQVTGGWRDLSLKNIRYEQPGVAVNAGEIHLAVGLDCLWRSSLCVNDLALKDIN
                     VAIDSKKMPPSEPAQEEEESGPLNLSTPWPITLSRVALNNINIKIDDTTVSVLDFTYG
                     LAWQEKNLTLKPTRLQGLLIALPKVAEVAQEEVVEPKIEKPQPDEKPLGETLKDLFAK
                     PVMPEMTDVHLPLNLNIESFRGEQLRITGDTDLTVRTMLLKVSSIDGNMKLDTLDIDA
                     NQGTVKASGTAQLANNWPVDITLNSTLNIDPLKGEKIKLKVGGALREQLEVRVNLSGP
                     MDVALRAQTRLAEAGLPLNLEVVSQRIAWPLTGDTQFQADDLKLKLSGKMTDYTLSMR
                     TAVKGQDIPPATITLDAKGNERQINLDKLTVAALEGKTELKALVDWQQAISWRGELTL
                     NGINTAKEIPDWPAKLNGVMKTKGSLYGGTWQMDVPELKLTGNVKQNSVNVNGTLKGN
                     SYMQWTIPGLHLALGPNSADIKGELGVKELNLDAAIDAPGLDNALPGLGGMAKGIVKV
                     RGTVEAPQLLADITAHGLRWQELSIAQARIEGDIKSTDQIAGHLNVRVERISQPDVNI
                     NLVTLDAKGSEKQHQLQLRVQGEPVSGQLSLTGSFDREEARWKGTLSDTRFQTPVGPW
                     SLTRAIALDYRNKEQEISIGPHCWLNPNAELCIPQTIDAGAAGRALVNLNRFDLAMLK
                     PFMPDTTQASGVFSGKADVSWDTTQEGLPQGKVTLSGRNVKVTQTVNDAPLPVAFETL
                     NLSADLHNNRAELGWLIRLTNNGQFDGQVQVTDPQGRRNLGGNVNMRNLNLAMVNPVF
                     LRGEKAAGMLNARLRLGGDVQSPQLFGQLQLSALDIDGNFMPFEMQPSQLAMNFSGTR
                     STLAGIVRTQQGQINLNGNADWSQIDNWRARVTAKGSRVRITVPPMVRLDVSPDVVFD
                     ATPSLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNNDLQPETPQTASIPINSNL
                     TVHVGNNVRIDAFGLKARLTGDLKVAQDKQGLGLNGQINIPDGRFRAYGQDLLVRKGE
                     LLFSGPPDQPLLNIEAIRNPDATEDDVIAGVRVTGTADEPKAEIFSDPAMPQAEALSY
                     LLRGQGLDSNQSDSAAMTSMLIGLGVAQSGQVVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSLATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            7945..8289
                     /locus_tag="OPY25_001308"
     CDS             7945..8289
                     /locus_tag="OPY25_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HCS0926960.1"
                     /translation="MRIFVYGSLRQKQGNSHWMTNAQLLGDYRIDNYQLYSLGHYPGA
                     VPGNGAVYGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLTL
                     IESGDWLDRNQP"
     gene            complement(8343..9551)
                     /locus_tag="OPY25_001309"
     CDS             complement(8343..9551)
                     /locus_tag="OPY25_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0926961.1"
                     /translation="MTSMQKWLRIGATLMFGLFVAYLDRSNLSVTLPTITHDLNIDGA
                     TASIVLTIFLIGYAFSNIFGGVFTQRYDPKKIVILMVLIWSIATVFVGFTSSVYVILI
                     CRLVLGITEGIYWPQQSRFASDWFSDKERTQANSIIQYYGQFLALGLGFMILSPLDAA
                     FGWRNVFIITGMIGIVVVVPLYITMLKKQEEAPYYRAPAPTEKTKLTLESLGGTPFLL
                     LIFTYITQGMLFWGITLWIPMVVNSLGYTGFSKALVSSLPYLTAVILAIPISWISDKT
                     QKRVLIASLGLLIPGVMLFLLPFVDAPGFKITLITLAMGYYAASFTPNIWSIIQSNVK
                     PHAIGPASGIINGIGAGGGGTLAGLMVGYFYRTTGSYMQGFMVLGCIVILGGASLLIY
                     GRIRAHHARR"
     gene            complement(9548..10711)
                     /locus_tag="OPY25_001310"
     CDS             complement(9548..10711)
                     /locus_tag="OPY25_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallo-dependent hydrolase"
                     /protein_id="HCS0926962.1"
                     /translation="MMKNDILITGGHIIDPARNINEINKLRIINDIIVDADKYPVTSE
                     TRIIHADGMIVTPGLIDYHTHVFYDATEGGVRPDMYMPPNGVTTVVDAGSAGTANFDA
                     FYRTVICASKVRIKAFLTVSPPGQIWSQENYDPDNIDENKIHALFRQYRNVLQGLKLK
                     VQTEDIAEYGLKPLTESLRIANDLRCPVAIHSTHPVVPMKELVSLLRRGDIIAHAFHG
                     KGSTILTNEGAVLAEVRHARERGVIFDAANGRSHFSMNTARRAIANGFLPDIISSDLS
                     TITKLAWPVYALPWILSKYLALGVTLADVINACTHTPAVLMGMAAEIGTLAPGAFADI
                     AIFKLKNRHVEFADIHGETLTGTHVLVPQMTIKSGEILFRQIDFGTRPNGVEK"
     gene            complement(11121..11651)
                     /gene="ppa"
                     /locus_tag="OPY25_001311"
     CDS             complement(11121..11651)
                     /gene="ppa"
                     /locus_tag="OPY25_001311"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HCS0926963.1"
                     /translation="MSLLNVPAGKELPEDIYVVIEIPANADPIKYEVDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGAVIRCRPVGVLKMTDESGE
                     DAKLVAVPHTKLSKEYDHIKDVNDLPELLKAQITHFFEHYKDLEKGKWVKVDGWDNAE
                     AAKAEIVASFERAAKK"
     gene            complement(11878..12876)
                     /gene="fbp"
                     /locus_tag="OPY25_001312"
     CDS             complement(11878..12876)
                     /gene="fbp"
                     /locus_tag="OPY25_001312"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HCS0926964.1"
                     /translation="MKTLGEFIVEKQHEFSQATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASCAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLIYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDSSTSRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPQGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPESLHQRRSFFVGNRHMVDDVERFIREYPDA"
     gene            13051..14424
                     /gene="mpl"
                     /locus_tag="OPY25_001313"
     CDS             13051..14424
                     /gene="mpl"
                     /locus_tag="OPY25_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HCS0926965.1"
                     /translation="MRIHILGICGTFMGGLAMLARSLGHEVTGSDANVYPPMSTLLEK
                     QGIDLIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPFMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEACGYKPGFVIGGVPGNFEVSARLGESPFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMALGCWSEQELVGEQGHWQAKKLTTDTSEWEVWLDGEKVGDVKWGLV
                     GEHNMHNGLMAIAAARHVGVAPAEAASALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGLCKDDLAPSLGRADEVFLLQPPHI
                     PWQVSEVADACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKALVVG"
     gene            complement(14531..15082)
                     /locus_tag="OPY25_001314"
     CDS             complement(14531..15082)
                     /locus_tag="OPY25_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HCS0926966.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     ELVDLGKNALDKIPLDADLRDAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLEHLRDRLIVEGDDAVAEVLTLWPHADRQQLRSLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            15178..16530
                     /gene="pmbA"
                     /locus_tag="OPY25_001315"
     CDS             15178..16530
                     /gene="pmbA"
                     /locus_tag="OPY25_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HCS0926967.1"
                     /translation="MAFAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFDAPDLDLFHPAEVTPDEAIELAARAEQASLKADKRITNTEG
                     GSFNSHYGIKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMADLQA
                     PEWVGAECARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGAVYRKSTFL
                     LDSLGKQILPEWLTIEEHPHLLKGLASSPFDSEGVRTERRDIVKDGVLTQWLLTNYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLNFEQLLKEMGTGLVVTELMGQGVSGITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKEMWRNIVTVGDDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            16628..17014
                     /gene="cybC"
                     /locus_tag="OPY25_001316"
     CDS             16628..17014
                     /gene="cybC"
                     /locus_tag="OPY25_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HCS0926968.1"
                     /translation="MRKSLLAILAVSSLVFGSAVFAADLEDNMDILNDNLKVVEKTDS
                     APELKAALTKMRAAALDAQKATPPKLEDKAPDSPEMKDFRHGFDILVGQIDGALKLAN
                     EGNVKEAKAAAEALKTTRNTYHKKYR"
     gene            17292..17630
                     /locus_tag="OPY25_001317"
     CDS             17292..17630
                     /locus_tag="OPY25_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine dehydrogenase"
                     /protein_id="HCS0926969.1"
                     /translation="MRRVDNGAVKHDAGERINELAEQVLTQVDGLLGRHHIVPNAVQT
                     QMLTSHVRAMAHRSITGEPLPEVDASLFDEISAESMALAREIVAAFGNLPDEEAWLLS
                     VHFEVAKDNL"
     gene            17641..18003
                     /locus_tag="OPY25_001318"
     CDS             17641..18003
                     /locus_tag="OPY25_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0926970.1"
                     /translation="MEQITVVIGDRLGKGQKVAAGVEKAGGRAVVVPGVAADMKLGDV
                     MKAENATFGISFCGSGGAGAITAQNKHGYKAKYGMRSVDEGVTAINEGCNVLGFGFMD
                     KEELGERLVQAWQKKYGA"
     gene            18003..18305
                     /locus_tag="OPY25_001319"
     CDS             18003..18305
                     /locus_tag="OPY25_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HCS0926971.1"
                     /translation="MMKEQFTTTVRVKGKGDAKARAFADALNHVQSAVMRESPYILLR
                     IEPQDVRIVQAHESVRKEAFLFFFLRRERRTYSVELDVAVNVTAINLDRVDFVAKR"
     gene            18328..19104
                     /locus_tag="OPY25_001320"
     CDS             18328..19104
                     /locus_tag="OPY25_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HCS0926972.1"
                     /translation="MFLIILIKSLIIGALVGVGVGAGAARMFHAPTTQGMGAFRTLGE
                     LNSCEGDPASHFSFGLGFFFNAWASSVAAGSFTQDVDHRIIPNWGAAALMIKNRNVGE
                     TLHDPKKMAIACAVIGMIVVTFLNLTASSVPEALQVTAVKVLVPAANLLVNIVMPVIF
                     WLAAIDAGKKSGFWATVFGGAAQLIMGNAVPGLVLGILIGKGVEESGWNHVTKVMMVA
                     IVLLFVLSGFFRGFDMKMIESFNMTVPNWLELIHNSLSGK"
     gene            19116..19760
                     /locus_tag="OPY25_001321"
     CDS             19116..19760
                     /locus_tag="OPY25_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HCS0926973.1"
                     /translation="MEENKGFWYADWSFPIFVGLLSSGVFAGTHMYYLYGIGAFNEVA
                     FVAMLKAGMDTGVYGAVAAFGASFLFARIIEGSLVGILDIGGAIQTGVGLGVPALLLG
                     AGFVFPVANFIASLITGLVIGLAIGYIIILARKFTINQSDSTYGADVMMGAGNTSGRF
                     LGPLIILSAMTASIPIGLGSLVGALLFYIWQKPITGGAILGAMILGSIFPVSIS"
     gene            19819..20952
                     /locus_tag="OPY25_001322"
     CDS             19819..20952
                     /locus_tag="OPY25_001322"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HCS0926974.1"
                     /translation="MFDLLLRHARLVDDTLTNIALQDGKIAALGDVDGPALKTIDLRG
                     ECYVSAGWIDSHVHCYPKSPIYHDEPDSVGIATGVTTVVDAGSTGADDIDDFYTLTRD
                     AATEVYALLNVSRVGLIAQNELANMANIDADAVRQAVKRHPDFIVGLKARMSSSVVGV
                     NGITPLERAKAMQQENGNLPLMVHIGNNPPDLDEIAERLTAGDIITHCYNGKPNRILR
                     PDGELRASVTRALARGVRLDVGHGTASLSFAVAKRAISLGILPHTISSDIYCRNRING
                     PVHSLANVMSKFLAIGMSLPQVIACVTANAADSLNLKTKGRLQPGLDADLTLFTLKRQ
                     PTVLVDAENDSLQAEELLTPLAAIRAGKGYMTEQGSAEHAFDF"
     gene            20936..22054
                     /locus_tag="OPY25_001323"
     CDS             20936..22054
                     /locus_tag="OPY25_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HCS0926975.1"
                     /translation="MPSIFEKYQLKQVINASGRMTALGVSTPRPEVIDAAMAGMNQYF
                     EMKDLVNKTGEYIAKLLEVEGATVVSCASAGLAQSVAAVLVQDSDWLLENLHVTPIEN
                     NEIVLPKGHNVNFGAPVGTMVALGGGKLVEAGYANECSAAQLAAAITPRTAAILYIKS
                     HHCVQKSMLSVEQAAVVARTHNLPLIVDTAAEEDLQCYYRVGADLVIYSGAKAIEGPT
                     SGLVIGKTQYVEWVKRQSAGIGRAMKVGKEGIVGLTCAIELYLRAQKESGAEMVEKMA
                     PFIDTLNTFNGVSARVVWDSAGRDIARTEIKFDEAVTGIATGDLVDALKQGEYAIYFR
                     GYKANEGIIEADVRSVDRAQLAIVARRIGEVINQEKQA"
     gene            22051..22791
                     /locus_tag="OPY25_001324"
     CDS             22051..22791
                     /locus_tag="OPY25_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463308.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HCS0926976.1"
                     /translation="MKLTPNFYRDRVCLNVLAGSKDNAREIYAAAEGHVLVGVLSKNY
                     PDVASAVADMREYAALIDNALSVGLGAGDPNQSAMVSEISRQVQPQHVNQVFTGVGGS
                     RALLGQNETVVNGLVSPTGTPGLVKISTGPLSSRAPDGIVPIETAIALLKDMGGSSVK
                     YFPMGGLTCRDEYKAVADACARHDFWLEPTGGIDLENFAEILHIALDAGVSKIIPHIY
                     SSIIDKVSGNTRADDVRQLLAIVRSRVG"
     gene            22808..24721
                     /locus_tag="OPY25_001325"
     CDS             22808..24721
                     /locus_tag="OPY25_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCS0926977.1"
                     /translation="MRFPNQRLAQLFAMLQNETLPQDELAQRLSVSTRTVRADIAALN
                     MLLTPHGAQFTLSRGNGYQLKIDDPARYQSLQTQQSPTLARGPRTSQERIHYLLARFL
                     TSAFSLKLEDLADEWFVSRATLQNDMADVREHLLRYHLTLETRPRHGMKLFGGEMAIR
                     ACLTDLLWTLVQQEPSHPLIVSTTLNTEVSQRLQSLLPDIFSHCQIRLTDEGELFLRL
                     YCAVAVRRIREGYPLSECVAEEVDEKVRHAAHEIAELLQQLADKPLSEPEVSWLKVHI
                     AARQVQEIAPSAINADDEEALVHYILNFINTQYNYNLLNDKQLHADLLTHIKTMITRV
                     RYQIMIPNPLLENIKQHYPMAWDMTLAAISSWGKYTPYTISENEIGFLVLHIGVGLER
                     SYNIGYQRQPQVLLVCDAGNAMVRMIEAVLARKYPQIEIARTLTLRDYEARDSMVEDF
                     VISTARIGEKDKPVIMIAPFPTDYQLEQIGKLVLVDRTRPWMLDKYFDASHFRIVEGE
                     INQQTLFKTLCDQLHEEGFVDAAFLDSVIEREAIVSTLLGDGIALPHALGLLAKKTVV
                     YTVLAPQGIAWGDETAHVIFLLAISKSEYEEAMAIYDIFVTFLRERAMTRLCACQNFT
                     QFKTVAMECVSRF"
     gene            24799..25041
                     /locus_tag="OPY25_001326"
     CDS             24799..25041
                     /locus_tag="OPY25_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCS0926978.1"
                     /translation="MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRM
                     PVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL"
     gene            25031..25315
                     /locus_tag="OPY25_001327"
     CDS             25031..25315
                     /locus_tag="OPY25_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCS0926979.1"
                     /translation="MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARL
                     NGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGKREHSAVYHDANKRL"
     gene            complement(25319..25783)
                     /gene="nrdG"
                     /locus_tag="OPY25_001328"
     CDS             complement(25319..25783)
                     /gene="nrdG"
                     /locus_tag="OPY25_001328"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HCS0926980.1"
                     /translation="MRYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRLNSG
                     QPFTKEMEDKIIADLNDTRIHRQGISLSGGDPLHPQNVPDILALVQRIHAECPGKDIW
                     VWTGYRLDELNAAQMQVVNLINVLVDGKFVQDLKDPALIWRGSSNQVVHHLR"
     gene            complement(25904..28042)
                     /gene="nrdD"
                     /locus_tag="OPY25_001329"
     CDS             complement(25904..28042)
                     /gene="nrdD"
                     /locus_tag="OPY25_001329"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCS0926981.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAGVDDADYCATVAE
                     VVSSQMNARSQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIQREKRGRLNQEI
                     RGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTESYNKHRKTADEWQIPDAEGYARSRTEKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQASILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDETAFWKLLDERLALARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLKADDDVSEIFKNGRASISLGYIGIHETINALFGGEHLY
                     DSEQLRAKGIAIVERLRQAVDQWKDETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKISFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            complement(28451..30103)
                     /gene="treC"
                     /locus_tag="OPY25_001330"
     CDS             complement(28451..30103)
                     /gene="treC"
                     /locus_tag="OPY25_001330"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCS0926982.1"
                     /translation="MTIPLWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTQRLDYLQRL
                     GVDAIWLTPFYISPQVDNGYDVANYTAIDPTYGTLDDFDELVAQAKARGIRIILDMVF
                     NHTSTQHAWFREALNKESPYRQFYIWRDGTPDVCPNNWQSKFGGSAWRWHSQSEQYYL
                     HLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLIAKDQDFPDDPTGDG
                     RRFYTDGPRTHTFLREMNRDVFTPRNLMTVGEMSSTTLENCQQYAALSGDELSMTFNF
                     HHLKVDYPNGEKWTLAKPDYVALKALFRQWQQGMHNVAWNALFWCNHDQPRIVSRFGD
                     EGEYRVPAAKMLAMALHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESHNMFAALRA
                     AGRDPDELLAILASKSRDNSRTPMQWDNGKNAGFTQGEPWISLCDNYTEVNVAAALRD
                     ENSVFYTYQKLIALRKTQPVMIWGDYQDLLPGSPSVWCYRRQWQGQTLLVVANLSDQC
                     QEWHPPHIKGQWQALLHNYGEVASQPAAMTLRPFEAIWWLQR"
     gene            complement(30153..31571)
                     /gene="treB"
                     /locus_tag="OPY25_001331"
     CDS             complement(30153..31571)
                     /gene="treB"
                     /locus_tag="OPY25_001331"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HCS0926983.1"
                     /translation="MSKVKQADIDRLIDLVGGRDNIATVSHCITRLRFVLHQPANARP
                     KEIEQLPMVKGCFTNAGQFQVVIGTEVGDYYNALLETTGKAYADKEQAKKAARQNMKW
                     HEQLISHFAEIFFPLLPALISGGLILGFRNVIGDVPMSHGQTLAQMHPALKTLYDFLW
                     LIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQTPDVWNFG
                     VFSIEKIGYQAQVIPALLAGLALGFIETRLKRIVPDYLYLVVVPVCSLILAVFLAHAF
                     IGPFGRMIGDGVAFAVRYLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDMQMVQS
                     MGGTPVWPLIALSNIAQASAVVGIIISSRKHNEREISVPAAISAYLGVAEPAMYSINI
                     KYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPTYWQVFAMAMVIAIV
                     IPVILTTFIYQRKHRQGTLQIV"
     gene            complement(31709..32656)
                     /gene="treR"
                     /locus_tag="OPY25_001332"
     CDS             complement(31709..32656)
                     /gene="treR"
                     /locus_tag="OPY25_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HCS0926984.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSKRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPMLVMEHLGMLRRRNIDGVVLFGFTGITEELIAPWKASLVLLARDAQGFASVCYDDE
                     GAIHILMQRLYEQGHRNISFLGVPHSDITTGKRRHDAYLAFCKKHKLHPVAALPGLAM
                     KQGYEHTASVIMPDTTALVCATDTLALGASKYLQEQRIETLQLASIGNTPLIKFLHPE
                     IVTVDPGYAEAGRQAALQLIEQINGRCDPRRIVIPSTLA"
     gene            32801..32899
                     /gene="mgtL"
                     /locus_tag="OPY25_001333"
     CDS             32801..32899
                     /gene="mgtL"
                     /locus_tag="OPY25_001333"
                     /inference="COORDINATES: protein motif:HMM:NF028369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HCS0926985.1"
                     /translation="MRIIRGANYLLTGGDMDPEPTPLPRWRIFLFR"
     gene            33040..35748
                     /gene="mgtA"
                     /locus_tag="OPY25_001334"
     CDS             33040..35748
                     /gene="mgtA"
                     /locus_tag="OPY25_001334"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCS0926986.1"
                     /translation="MLKTITRQLFARLNRHLPYRLVHRDPLPGAQTAVNATIPPSLSE
                     RCLKIAAMEQETLWRVFDTHPEGLNAAEVTRAREKHGENRLPAQKPSPWWVHLWVCYR
                     NPFNILLTILGGISYATEDLFAAGVIALMVGISTLLNFVQEARSTKAADALKAMVSNT
                     ATVLRVINENGENAWLELPIDQLVPGDIIKLAAGDMIPADLRIIQARDLFVAQASLTG
                     ESLPVEKVATTREPRQNNPLECDTLCFMGTNVVSGTAQAVVMATGADTWFGQLAGRVS
                     EQDNEQNAFQKGISRVSMLLIRFMLVMAPVVLIINGYTKGDWWEAALFALSVAVGLTP
                     EMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIMLENH
                     TDISGKPSEHVLHCAWLNSHYQTGLKNLLDTAVLEGVDETAARQLSGRWQKIDEIPFD
                     FERRRMSVVVAEDSNVHQLVCKGALQEILNVCTQVRHNGDIVPLDDNMLRRVKRVTDT
                     LNRQGLRVVAVATKYLPAREGDYQRIDESDLILEGYIAFLDPPKETTAPALKALKASG
                     ITVKILTGDSELVAAKVCHEVGLDAGDVVIGSDIEGLSDDALAALAARTTLFARLTPM
                     HKERIVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSL
                     MVLEEGVIEGRRTFSNMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLL
                     YDVSQVAIPFDNVDEEQIQKPQRWNPADLGRFMVFFGPISSIFDILTFCLMWWVFHAN
                     TPETQTLFQSGWFVVGLLSQTLIVHMIRTRRLPFIQSRAAWPLMAMTLLVMVVGVSLP
                     FSPLASYLQLQALPLSYFPWLIAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(35864..36310)
                     /locus_tag="OPY25_001335"
     CDS             complement(35864..36310)
                     /locus_tag="OPY25_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCS0926987.1"
                     /translation="MVRARFTEEQIADFLQQSKNGVPNKALCEEYGFSNSTLRRWQEK
                     HAESIRQELKQIESTAKIVFLCFIIAAILLTLMFPKPTAALAIPPYLVYCISYIRRFR
                     RISAKHIQRWDISSSRSGSGAENVFYKLSWTFLFFMPAYSILQLLE"
     gene            complement(36385..36771)
                     /gene="ridA"
                     /locus_tag="OPY25_001336"
     CDS             complement(36385..36771)
                     /gene="ridA"
                     /locus_tag="OPY25_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HCS0926988.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGSMVITSGQIPVDPKTGAVAE
                     DVSAQARQSLENVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(36848..37309)
                     /gene="pyrI"
                     /locus_tag="OPY25_001337"
     CDS             complement(36848..37309)
                     /gene="pyrI"
                     /locus_tag="OPY25_001337"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HCS0926989.1"
                     /translation="MTHDNKLQVEAIKCGTVIDHIPAQVGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLTDEQVNQLALYAPQATVNRIDNYDVVGKSRPSLPER
                     INNVLVCPNSNCISHAEPVSSSFAVKKRANDIALKCKYCEKEFSHNVVLAN"
     gene            complement(37322..38257)
                     /gene="pyrB"
                     /locus_tag="OPY25_001338"
     CDS             complement(37322..38257)
                     /gene="pyrB"
                     /locus_tag="OPY25_001338"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HCS0926990.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGQVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHIAM
                     VGDLKYGRTVHSLTQALAKFSGNRFYFIAPDALAMPQYILDMLDEKGMAWSLHGSIEE
                     VMADVDILYMTRVQKERLDPSEYANVKAQFVLRASDLNGARENMKVLHPLPRIDEITT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNSELSL"
     gene            complement(38293..38394)
                     /gene="pyrL"
                     /locus_tag="OPY25_001339"
     CDS             complement(38293..38394)
                     /gene="pyrL"
                     /locus_tag="OPY25_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HCS0926991.1"
                     /translation="MVQCVRHSVLPRLKKDAGLPFFFPLKTNTKPLN"
     gene            38374..38515
                     /locus_tag="OPY25_001340"
                     /pseudo
     CDS             38374..38515
                     /locus_tag="OPY25_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453732.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(38485..38973)
                     /locus_tag="OPY25_001341"
     CDS             complement(38485..38973)
                     /locus_tag="OPY25_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCS0926992.1"
                     /translation="MKEYDDYSAKEQQQLAVCQRLISEKSYLSQEEIRRDLQNEGFEG
                     ISQSTVSRLLKLLGAIKIRNAKGQKIYSVNPQQRPSPDAGRSIAEMVVSVEHNSEFIL
                     IHTAAGYGRAVARILDYHALPEILGVVAGSSIVWVAPQVVQRTALVHKQINYLLKMNL
                     NS"
     gene            complement(39160..40563)
                     /locus_tag="OPY25_001342"
     CDS             complement(39160..40563)
                     /locus_tag="OPY25_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCS0926993.1"
                     /translation="MGKFKFPTAYTILFILIALVAVMTWIVPAGKYQMAMNATLGKEV
                     PVAGTYAPVDAHPQGITAVLLAPIDGLYNHETYTAGAIDVALFVLIIGGFLGVVNKTG
                     AIDAGIERVTIKLNGKDEWMIPILMALFAAGGTIYGMAEESLPFYTLLVPVMMAARFD
                     PLVATATVLLGAGIGTLGSTINPFATVIAANAAGIPFTQGMLMRVLLLIVGYVLCVFW
                     VMRYARKVRAHPELSIVADKMAENRAHFLGNRANTLLEFTATRKWVLLIFAASFAVMI
                     YGVAVLGWWMAEISGVFLAAAIIVGVITRMGEEAFTSTFIDGARDLLGVALIIGIARG
                     IVVVMDNGMITHTILHSAESLVSGLSTTIFINVTYWLEVLLSFLVPSSSGLAVLTMPI
                     MAPLADFAHVQRDLVVTAYQSASGIVNLVTPTSAVVMGGLAIARVPYVRYLKWVAPLL
                     LILTLLNMAVLSIGAMM"
     gene            complement(40619..41623)
                     /gene="argF"
                     /locus_tag="OPY25_001343"
     CDS             complement(40619..41623)
                     /gene="argF"
                     /locus_tag="OPY25_001343"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCS0926994.1"
                     /translation="MVISLKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTL
                     IGKNIALIFEKTSTRTRCAFEVAAFDQGAQVTYLGPSGSQIGHKESMKDTARVLGRMY
                     DGIEYRGFGQHIVEELGEYAGVPVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSF
                     AYLGDARNNMGNSLMVGAAKMGMDIRLIAPKSFWPDAALVAQCREIASVTGARITLTE
                     SVEDGVHGVDFLYTDVWVSMGEPKEAWAERVSLMTPYQVNQQVVNATGNPDVKFMHCL
                     PAFHNEHTKVGREIEMAYGLKGLEVTEEVFESAGSMVFDEAENRMHTIKAVMVATLGD
                     "
     gene            complement(41735..42667)
                     /gene="arcC"
                     /locus_tag="OPY25_001344"
     CDS             complement(41735..42667)
                     /gene="arcC"
                     /locus_tag="OPY25_001344"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCS0926995.1"
                     /translation="MENKRTLVVALGGNALLKRGEPLEADIQRKNIELAARTIAQLTR
                     QWRVVLVHGNGPQIGLLALQNSAYANVTPYPLDILGAESQGMIGYMLQQALKNHLPER
                     EISVLLTQVEVDANDPAFLNPTKYIGPIYDEAQARALQAEKGWVFKADGNAFRRVVPS
                     SQPKRIVENDAIRALISRDHLVICNGGGGVPVVEKADGYHGIEAVIDKDLSAALLASQ
                     IHADALLILTDVDAVYLDWGKPTQRPLAQVTPELLREMQFDAGSMGPKVTACAEFVSH
                     CCGIAGIGSLADGQAILAGEKGTLIRCETADVDA"
     gene            complement(42678..43898)
                     /gene="arcA"
                     /locus_tag="OPY25_001345"
     CDS             complement(42678..43898)
                     /gene="arcA"
                     /locus_tag="OPY25_001345"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCS0926996.1"
                     /translation="MEKHFVGSEIGQLRSVMLHRPNLSLKRLTPSNCQELLFDDVLSV
                     ERAGEEHDIFANTLRQQGIEVLLLTDLLTQTLDVADAKAWLLDTQISDYRLGPTFAAD
                     IRAWLADMPHRELARHLSGGLTYGEIPASIKNMVVDTHDINDFIMKPLPNHLFTRDTS
                     CWIYNGVSINPMAKPARQRETNNLRAIYRWHPQFADGDFIKYFGDENINYDHATLEGG
                     DVLVIGRGAVLIGMSERTTPQGVEFLAQALFKHRQAERVIAVELPKHRSCMHLDTVMT
                     HIDIDTFSVYPEVVRPDVQCWTLTPDGRGGLKRTQESTLVHALETALGIDQVRLITTG
                     GDAFEAEREQWNDANNVLTLRPGVVVGYERNIWTNEKYDKAGITVLPIPGDELGRGRG
                     GARCMSCPLERDGI"
BASE COUNT        10185 a        11262 c        12324 g        10296 t
ORIGIN      
        1 aaaacggctc ctgaatcagg agccgttgat gtttctggca aacggatttc aggccgcgct
       61 gtcttcttta ccttgcgcat cgggcagttt cggcgccggt acgttgcttt tattgtcgag
      121 acgcgtcacc agcaactgat cgatacggta gttgtcgata tccaccactt caaatttgta
      181 gccggaaaac ttcaccgaat cagtacgttt tgggatcttg cgcagcataa acatcataaa
      241 gccgccaatg gtttcatagt tgccggattg cggaaactca tcgatatcca gcacgcgcat
      301 gacgtcgtca atcggcgtgc cgccgtcaac cagccaggaa ttttcatcgc gcgccacaat
      361 ttgctcttcc agtccctggc cgaccaggtc acccattagc gtggtcatca catcgttcag
      421 cgtaatgata ccgacgacca gcgcgtattc attcataatg accgcgaaat cttcgcccgc
      481 cgttttgaaa ctttccagcg cctcagaaag ggtcagcgta tccggcacaa tcaaggtatt
      541 gcgaatttgc acgccgctat tcagcgccat actttggttc gccagcacgc ggttcagcag
      601 atctttggaa tctacatagc cgatgatgtg gtcgatatct tcattacaca ccaaaaattt
      661 tgagtgcgga tgttcggcta cctttttctt caggctttgt tcgtcttcgt gtagatcaaa
      721 ccagatgata ctttcgcgcg acgtcataga agacggtacg gtgcgggatt caagttcaaa
      781 cacattttca atcagttcgt gctcttgctt gcgcaagacg cccgccagcg cgccggcttc
      841 caccaccgcg taaatatcat cagaagtaat gtcgtctttc cgcaccattg gaattttgaa
      901 caggcggaag atgttgtttg ccatgccgtt aaacagccac accagcgggc gaaaaacgaa
      961 caggcagaag cgcatcgggt tgatgatacg caaagccaca gcttctggcg caatcatacc
     1021 gatgcgtttc ggggttaaat ccgcgaacag gataaacagc cccgtcacca gcgagaaaga
     1081 gagaataaag ctcaactgct cggagagttc tggcgacata tagtgcgaga aaagggcgga
     1141 aaaggcgggc gaaaatgccg catcgccgac gataccgcca agaatagcga cggcgttcag
     1201 gccaatttgc acaacggtga aaaacatgcc gggattttcc tgcattttca atacgcgttg
     1261 tgcgttgata ctgccttcat cagctaataa cttaagttta atcttacgtg atgcggcaag
     1321 cgagatctcg gagatggaga agaacgcact tacagcgatc aggcagaata taatgaatat
     1381 actgtttaac atatcttatc cggcgaaacg ccagatcctc ggaagggaag tttataaatc
     1441 cgtgtggtaa cgtttaatga aaaccggctc gtagcagtga gccgataagt tcagggctag
     1501 tatagcgtaa gctactgtaa agtcgccaga gggttcattt tcaactccga caagttcccc
     1561 ctacgcctgc gtcgtcacgc gtcacgcgtc aggcggcagg caaacgccga tcccgccaat
     1621 cccgcagtaa ccgtatggat ttttgtgcag atactgttgg tgttcatcct cggcgtagta
     1681 aaacggcgtc gcatgggcga tttccgtggt aatagggcga tggtctccgg cggcggccat
     1741 tgccgactga aagcgctcgc gactggcgtg agcggcggca ttctgttccg gcgttaaggg
     1801 ataaatcgca gaacggtatt gcgtaccgtg atcgttaccc tgttgcatcc cctgcgtcgg
     1861 atcgtgattt tcccagaagg tctgtaaaag ctgctcataa cggataacgg caggatcgta
     1921 cactatccgt accgcttcgg catgaccggt ctgcccggag cagacttccc ggtaggttgg
     1981 attaggcgtg taaccgcccg cataccctgc tgcggtgcta tatacgccgg gcaattgcca
     2041 gaataaacgt tctacgcccc agaaacagcc catcgcgaag taggcgatct ccatcccggc
     2101 agggacattg gtcatagagt gttcatttac cgcatgcaga gtggcgattg gcatcggggt
     2161 gttgcgtcct ggtaacgcat ctgcttgagt aaccagatgt tttttatcaa ataaactcat
     2221 gaactattct cccgaaagcg ttaattggcg ttaaggttgt aacgagacgc atctttgcac
     2281 acaataacaa cattaatgta tctggattta accataagaa atatttgggc agtcgtctgc
     2341 ttttcaatcg aaattgttga ttttatgtta agccgcggag cggtagtgtg attttttcca
     2401 ggggtgggaa taggggatat tcaggagaaa atgtgccaca tatccgtcag ttatgttggg
     2461 ttagcttact gtgcctgagc agttctgcgg tagccgcaaa tgttcgtctg aaagtcgaag
     2521 ggctatccgg agagctggaa aaaaacgttc gcgcacagct ctctacgatt cagagcgatg
     2581 aggtgacgcc ggatcggcgc tttcgcgccc gagttgatga tgcgattcgc gaagggctta
     2641 aagcgttagg ctattacgaa cccactatca aattcgactt gcttccaccg cctgcgaaag
     2701 gacggcaggt attaatcgcc agggttacgc ccggccagcc ggtgttgatt ggcggtacag
     2761 aagtcatttt acgcggcggc gcgcgtacgg acaaagatta tctggcctta ctgaaaacgc
     2821 gtccggcaat cggcacggtg ctcaaccagg gggactatga caattttaaa aagtcgttaa
     2881 ccagcgtgtc gctacgcaaa ggctatttcg acagcgaatt cattaaaagt cagttgggaa
     2941 ttgctctggg ccgtcatcag gcgttttggg atattgatta tgatagcggt gagcgctatc
     3001 gcttcgggcc tgtcaccttc gaaggttcgc agattcgtga tgaatattta caaaatctgt
     3061 tgccgtttaa agagggtgat gagtacgaat cgaaagattt ggcggaacta aaccgccggc
     3121 tttccgctac cggatggttt aattctgttg tggtggcgcc ggaatttgag aaatcgcgta
     3181 aaacaaaaat tctgccgtta aaaggcgtgg tatcaccgcg aaccgaaaac acgattgaaa
     3241 ccggggtggg gtactccacc gacgtcgggc cgcgcgtgaa agcgtcgtgg aaaaaaccgt
     3301 ggatgaactc ctacggtcat agcctgacca ccagcaccag tatttctgcg ccggaacagg
     3361 tgctggattt tagttataaa atgccgctgc tgaaaaaccc gctggagcaa tactatctgg
     3421 tacagggcgg ttttaaacgt accgatttga atgatacgga gcaggactcg accacgcttg
     3481 ccgtgtcgcg ttactgggac ctttccagcg gttggcagcg ggcgattaac ctgcgctgga
     3541 gtttcgacca ctttacccag gggaacgtca ccaataccac catgctgttc tacccgggcg
     3601 tgatgatcag ccgaacccgc tcgcgagggg gactgatgcc aacctggggc gattcgcagc
     3661 gctactcggt agactattcg aatacggcct ggggctccga cgtggatttc tccgtactgc
     3721 aggcgcaaaa cgtctggatt cggactttgt acgatcgcca ccgttttgtg atgcgcgcca
     3781 atttgggctg gatagaaacc ggtgatttcg acaaagttcc gccggattta cgtttcttcg
     3841 ccgggggcga ccgcagtatt cgcggctata aatacaaatc tatttcgcct aaagatagcg
     3901 acggcaatct taaaggcgcc tcaaaactgg caaccggatc gctggagtac cagtataacg
     3961 tcaccggcaa atggtggggg gcggtgtttg tcgatagcgg cgaggcggtt agtgatattc
     4021 gccgtagcga tttcaaaacc gggaccgggg tcggcgtgcg ctgggcgtcg ccggttgggc
     4081 ctgtcaaact cgattttgcc gtaccggtcg gcgacaaaga cgaacacggt ttacagtttt
     4141 atatcggtct ggggcctgaa ttatgagttt atggaagaaa ataagcctcg gcgtgttgat
     4201 tttcattgtg gtgttactgg cgagcgttgc gtttctggtc gggacgacga cggggctgca
     4261 tctggtattc ggtgcggcga accgctgggt gccggggctg gatattgggc aggtcaccgg
     4321 cggctggcgg gacttatcgt taaaaaatat ccgctatgag cagccgggcg ttgcggtaaa
     4381 tgcgggcgaa attcatctgg ccgtcgggct tgattgcctg tggcgcagta gcctgtgcgt
     4441 caatgatctg gcgctaaaag acattaatgt cgctatcgac agcaaaaaaa tgcctccttc
     4501 cgaaccggcg caagaagagg aagaaagcgg gccgctgaac ctctccacgc cctggcccat
     4561 cacgctgtcg cgcgtggcgc tgaataacat caatatcaag attgatgaca ctaccgtttc
     4621 ggtgctggat tttacctacg ggctggcatg gcaggagaaa aacctgaccc tgaaaccgac
     4681 gcggcttcag ggactgctga tcgcgctgcc gaaggtcgct gaggtggcgc aggaagaggt
     4741 ggttgaaccc aaaatcgaga aacctcaacc ggatgaaaag ccgcttggcg aaacgctaaa
     4801 agatctgttt gcaaaaccgg taatgccgga gatgaccgat gttcacctgc cgctcaatct
     4861 gaatatcgag tcatttcgcg gcgagcagct acgcatcacc ggcgataccg atctgacggt
     4921 gcgcacgatg ctgcttaaag tcagcagtat cgacggtaat atgaagctgg atactctgga
     4981 tatcgacgcc aaccagggca cggtgaaagc ctccggtacg gcgcagctcg ccaataactg
     5041 gccggttgat attacgctca acagtacgct gaatatcgat ccgctaaagg gtgaaaagat
     5101 caaactcaag gtcggcggcg cgttacgcga acaactggag gtcagggtga acctttccgg
     5161 gccgatggat gtcgcgcttc gcgcccagac gcggctggcg gaggccggtt taccgctcaa
     5221 tcttgaggtc gtcagccaac gcattgcctg gccattgacg ggtgataccc agtttcaggc
     5281 tgacgatctg aagctcaaac tgagcggtaa gatgaccgac tatacgttgt cgatgcgaac
     5341 cgccgtgaaa ggacaagata ttccgccggc gaccatcacg ctggatgcta aagggaatga
     5401 gcggcagatt aatctcgata aactcaccgt cgccgctctg gagggaaaaa ccgaactgaa
     5461 agcgctggtg gactggcagc aggcgattag ctggcgtggc gaactgacgc tgaatggcat
     5521 caataccgct aaagagatcc cggactggcc cgcgaaactt aacggcgtca tgaaaaccaa
     5581 aggcagcctc tacggcggca cctggcagat ggatgtcccg gagctcaagc tgaccggtaa
     5641 tgtgaagcag aacagcgtta acgtcaacgg gacgctaaag ggcaacagct acatgcagtg
     5701 gacgatcccg gggctgcacc ttgcgctggg cccaaacagc gccgatataa aaggcgagct
     5761 tggcgttaag gagctgaatc ttgacgccgc catcgatgcg ccagggctgg ataatgcgct
     5821 gccagggctg ggcggcatgg caaaaggaat cgttaaagtc cgcggtacgg tagaagcgcc
     5881 gcagctgttg gcggatatca ccgcccacgg tctgcgctgg caggagctgt ctatcgccca
     5941 ggcgcgcatc gagggcgata ttaaatccac cgatcagata gcgggccatc tcaacgttcg
     6001 cgtagagcgg atttcgcagc ccgacgttaa catcaatctg gtgacgcttg acgccaaagg
     6061 cagcgagaag cagcatcagc tacagctccg tgttcaggga gaaccggtat ccggtcaact
     6121 ctccctgaca ggcagttttg atcgcgagga ggcgcgctgg aaagggacgt taagcgacac
     6181 ccgtttccag acgccagtgg ggccatggtc gttgacccgc gcgattgcgc tggactaccg
     6241 taataaagaa caggaaatca gtatcgggcc acattgttgg ctgaacccga acgccgagct
     6301 gtgcatcccg caaaccattg atgcgggcgc cgcaggacgg gcgttggtca atctcaaccg
     6361 ctttgatctg gcgatgctga agccatttat gcctgatacc actcaggcca gcggggtctt
     6421 tagcgggaaa gcggacgtgt cgtgggacac cacccaggag ggattgccgc aggggaaggt
     6481 cacactttcc ggtcgtaacg tgaaggtcac gcagaccgtc aatgacgcgc cgttaccggt
     6541 cgcgtttgag acgctgaacc tcagcgccga tctgcacaat aatcgcgccg agctgggatg
     6601 gctgattcgc ctgacgaaca atggtcaatt cgatggccag gtgcaggtaa ccgatcctca
     6661 ggggcggcgc aatctcggcg gtaacgtcaa catgcgcaat ctcaatctgg cgatggtcaa
     6721 ccctgtcttt ttgcgcggcg aaaaagcggc gggaatgtta aacgccaggc tacgtctggg
     6781 cggcgatgtg caaagcccgc agttgtttgg tcagttgcag cttagcgcgc tggatattga
     6841 cggtaatttt atgccgtttg agatgcagcc gagccagctc gccatgaact ttagcggtac
     6901 gcgctcgacg ctcgctggta tcgtgcgaac acaacaaggg caaattaacc tgaacggtaa
     6961 cgccgactgg agccagattg acaactggcg cgcgcgggtg acggcgaaag gcagtcgggt
     7021 gcggattacc gttccgccga tggtgcgcct ggatgtctcg ccggatgtgg tctttgacgc
     7081 gacgccttcg ctgttcacgt tggatgggcg tgtggacgtt ccgtgggcac gaattgtggt
     7141 gcacgacctg ccggagagcg cggtcggcgt ctccagcgat gtggttatgc tcaataatga
     7201 cctgcaacca gaaacgccgc agacagcatc tattcccatc aacagtaatc tgacggtaca
     7261 tgtcggcaac aacgtgcgca tcgacgcctt cgggcttaaa gcgcgtttga ccggcgattt
     7321 gaaagtcgcg caggataagc aggggctggg gctaaatggt caaatcaata ttcctgacgg
     7381 ccgattccgc gcctacggcc aggacctgct tgttcgtaaa ggcgagctgc tgttctccgg
     7441 cccgccggat cagccgctgc tcaatatcga agcgatccgt aaccctgacg ccaccgaaga
     7501 cgatgtcatt gcgggcgtgc gcgtcacagg cacagctgat gaacccaaag cggaaatctt
     7561 ctccgatccg gcgatgccgc aggctgaagc gctttcttat ctgctgcgtg ggcaggggtt
     7621 ggacagcaat cagagtgata gcgcagcaat gacttccatg cttattggcc tgggggttgc
     7681 gcaaagtggt caggttgtgg gtaaaatcgg agagacattc ggtgtaagta atctggcgct
     7741 ggacacgcaa ggggtgggcg attcgtccca ggttgtggtc agcggctatg tactgccggg
     7801 tctacaggtg aagtatggtg tagggatatt tgactctctg gcgacgctca cgttacgtta
     7861 tcgcctgatg cctaagctat atctggaagc agtgtctggc gtagatcagg cacttgattt
     7921 gctctatcag tttgagtttt agcaatgcga atatttgtct atggcagttt acgacagaaa
     7981 caaggcaaca gtcactggat gaccaatgcc caattgcttg gcgattaccg tatcgataac
     8041 taccagttgt atagtctggg ccactatcca ggcgcagttc cgggaaacgg agcggtatac
     8101 ggtgaagttt atcgaattga taacgccacg ctggccgaac ttgatgcttt gcgcaccagg
     8161 ggcggtgaat acgcacgcca gttaatccag acgccttacg gcagcgcatg gatgtatgta
     8221 tatcaacgtc ctgttgatgg gttaactctg attgaaagcg gtgactggtt agacagaaac
     8281 cagccctgaa ctgaacacgc caccctcggg tggcgttgtt ttttacattc tggctgatgg
     8341 cgttaacgcc gggcatggtg agctcttatt ctgccgtaga tcaataatga cgcgccgccc
     8401 aggataacaa tgcatccgag aaccataaat ccctgcatat agctgccggt tgtccggtaa
     8461 aaatagccga ccattaggcc tgccaacgta ccgccgccgc cggcgccgat gccattaata
     8521 ataccggagg ctgggccaat cgcatggggt ttaacgttcg actggataat cgaccagata
     8581 ttgggggtaa agctggcggc ataataaccc atcgccaggg taatgagcgt gattttaaag
     8641 cccggcgcat cgacaaatgg caggagaaat aacatcacgc cggggattag taggcccagt
     8701 gaagcaataa gtacacgttt ttgtgtctta tcactgatcc atgagatggg gattgccagt
     8761 ataaccgcag tcagataagg cagagaactg accaatgctt tactgaatcc ggtatagccg
     8821 agagaattga caaccatggg gatccataac gtaattcccc agaacaacat cccttgagtg
     8881 atgtaggtaa aaataaggag taggaagggg gttccgccca gcgattccag agtaagttta
     8941 gttttctctg ttggcgccgg cgcacgataa taaggcgctt cttcctgttt tttcagcatt
     9001 gttatataaa gtggaaccac aacaacaatg ccgatcatac cagtgataat aaaaacattt
     9061 cgccaaccga aggcagcatc cagcggggac aaaatcataa atcccaggcc taatgccagg
     9121 aactgtccat aatactggat aatgctgttc gcctgcgtcc gttctttgtc tgaaaaccag
     9181 tcgctggcga agcgggactg ctgcggccaa taaatgcctt cggtaatgcc aagcaccagc
     9241 cgacaaatca aaataacgta cactgacgag gtaaatccga caaaaacggt cgcaatcgac
     9301 cagattagca ccatcagaat gactattttt ttcggatcgt atcgctgggt aaatacgccg
     9361 ccaaaaatat ttgaaaaggc atagccaata agaaatatgg ttaatacaat gctggccgtt
     9421 gcgccatcaa tattcaggtc gtgtgtaatc gtaggtaacg taacggaaag attagaacgg
     9481 tcaagataag caacaaaaag gccgaacatt aatgtcgcgc cgatccgtag ccatttttgc
     9541 attgaggtca tttttcaact ccgtttggcc gcgtgccaaa atcaatttga cgaaataata
     9601 tctcaccgga ttttatggtc atttgtggta ccagcacatg cgtccccgtg agcgtttcac
     9661 catgaatatc ggcaaattca acatgcctgt tttttaattt aaagatggcg atatcggcaa
     9721 atgccccagg ggccagcgta ccaatttctg ctgccatacc cattaaaact gctggggtat
     9781 gggtacaggc gttaatgaca tcggcaagcg tgacgccgag tgctaaatat ttcgataaaa
     9841 tccatggtaa ggcgtaaaca ggccaggcga gtttagtgat ggttgagaga tcgctactga
     9901 tgatatccgg aagaaagcca ttggcgatgg cccggcgtgc cgtgttcatt gaaaaatggc
     9961 tgcgaccatt ggcggcatca aatataacgc ctcgttctct tgcatgacgg acttcggcta
    10021 agaccgcgcc ttcattagta agaatggtgc tacctttgcc gtgaaacgca tgagcgataa
    10081 tatcgccgcg gcgtagcaag gagacaagtt ctttcatggg aacgacggga tgagtcgagt
    10141 gtattgctac ggggcacctt aaatcgttgg caatacgaag ggattcagtc agcggtttta
    10201 agccatattc agcaatgtcc tcagtctgaa ccttgagttt taatccctga agaacgttgc
    10261 gatactggcg aaacagcgcg tggatcttat tttcatcaat attgtcagga tcataatttt
    10321 cttgtgacca gatttggccc ggcggcgaca cggtcagaaa cgctttgatt cgaactttgc
    10381 tggcgcaaat caccgttcgg tagaaggcat caaagtttgc cgtaccggca gaacctgcat
    10441 ccacgacggt ggtgacgcca ttcggcggca tgtacatatc aggcctgacg ccgccttccg
    10501 tcgcatcata aaaaacatgc gtgtgataat cgataagacc gggagtgacg atcatgccgt
    10561 cggcatggat aatccgggtc tccgaagtta caggatattt atcggcatca acgataatat
    10621 cgttaatgat gcgtaacttg ttaatctcat taatattacg agcgggatcg atgatatgtc
    10681 caccggtaat taatatatca tttttcatca taatctctta aaatagtaaa taattatggc
    10741 agcccttgaa aatatattaa aaagtgtgtt ttgagcggat gttatgttgg attgaaaata
    10801 cagttattgg tagggagagc ttaggatacc ttattaaaaa ggtaatcggg cttatgcact
    10861 aaataagaat ttagcgcttg ctaatattta gggcgtaagt ccatgggagt ctgggggcat
    10921 tcgcaaaaca attattatct taagcttttt agagaaaacg tgagcgtatt caaccctttt
    10981 taataaaaaa taaggtaaag tcttattcat tctgtgaatg ttaaactaat aatgataaaa
    11041 attgtgttct attcattagc caataaaaag gccctcatta ctatgagagc ctttatcttg
    11101 acgattatgt aaaagcgaac ttatttcttc gctgcgcgct cgaaagaggc aacgatttcc
    11161 gctttagccg cttcggcgtt gtcccaaccg tcaactttca cccatttgcc tttttcgaga
    11221 tctttataat gctcgaagaa atgagtgatc tgcgctttca gcagttccgg cagatcgttc
    11281 acatctttaa tgtgatcgta ctctttgctc agtttggtgt gcggtacggc aaccagtttc
    11341 gcatcttcac cggattcgtc ggtcattttc agtacgccaa ccggacggca acggatgacg
    11401 gcgcctggct gcagcgggta cggcgtcggg accagaacgt ctaccgggtc gccgtccaga
    11461 gacagggtat ggttgatgta accgtagttg cacggataga acatcgcggt ggacatgaag
    11521 cggtcaacga acagcgcgcc gctctctttg tcaacttcgt atttgatcgg atctgcgtta
    11581 gccgggatct cgataacgac gtagatatct tccggcagtt ctttacccgc cgggacgttg
    11641 agtaagctca tgtctgtttc ctttgaagtt atgacaaaca agtggcgagt attatagcca
    11701 actcacgccg aaagtcttcg cttgttttcg tttccgcctc atctggcgcg tcgttgcgga
    11761 gcataaacga caaaggttaa gaaccgaaaa aatcacgggc ctgataaggc aacgccgcca
    11821 tcggacatct tattgcccaa tggcggcttc atgcgttatt ccgcatggtg gtaaagatta
    11881 cgcgtccggg tattcgcgga taaagcgttc cacatcgtca accatatggc ggttgccgac
    11941 gaagaacgag cggcgctggt gcaggctttc cggaatgata tccagaatac gttctttacc
    12001 atcgcttgct ttgccaccgg cctgttccgc gaggaacgcc atcgggttgc attcatacag
    12061 cagacgcagt ttcccctgcg gatggctggc ggtgctgggg tagagataga tgccgccttt
    12121 cagcaggttg cggtggaaat cggccaccag agagccaatg taacgtgagg tataagggcg
    12181 acttgttgaa ctatcctctt cctggcagaa tttgatgtac ttcttcacgc cattcgggaa
    12241 cttaatgtag ttgccttcgt taatggagta ggttttaccc ttttccggga aacgcatacg
    12301 ttcttggcac agacagaaca cgcccaacga cggatcgtag gtgaaagcgt gtacgccgca
    12361 gccggtggtg taaatcagca tggtggacga gccatacacg acatatcccg cagcgacctg
    12421 tttgttgccg ggttgcagga aatcttcttc ggtgaccggc gtgccgacgg gcgtcacgcg
    12481 gcgataaatc gagaaaatcg taccgacaga gacgttaacg tcgatgttag aagagccatc
    12541 cagagggtcc atcagcacca catatttcgc gtgttcgcag ccttcaaaga cgacaatttc
    12601 gtcctcttct tccgatgcga tgcccgctac aatatcgcgc gcttttagtg cagctttcag
    12661 tttctcgttc gcgaacagat cgagtttctg ctgaacctcg ccctgtacgt tctcagcaca
    12721 gctggcaccc aggatatcga ccagaccggc cttgttgata tcgcggtgga tgatcttggc
    12781 gcccaatttt attgccgaca gcaaagcagt gagctcaccg gtagcctgag agaactcgtg
    12841 ctgcttttcg acaataaatt cacctaacgt tttcataaca ctttccctgc aattgattgg
    12901 agtaaagcga ccgtaacaat cttaacaaac atttcagatg atgcgctcag gtgaatcgcg
    12961 ccagcaaagt acagatttac ctgaaatgcg tttctcactt gccagacatg tgcgtaaaat
    13021 ggctcgcaga taaaaaaagg atagtgacgt atgcgcattc atattttggg aatttgtggc
    13081 actttcatgg gggggctggc gatgctggct cgctcgcttg gtcatgaagt aacgggttcg
    13141 gacgccaatg tgtatccgcc gatgagtacc ttacttgaga agcaaggcat tgatctgatc
    13201 cagggttatg acgccagcca gctcgatccg cagccagatc tggtgattat cggcaatgcg
    13261 atgacgcgcg ggaatccgtg cgtggaagcg gtgctggaaa aaaacattcc ctttatgtct
    13321 ggtccacagt ggctgcatga ctttgtgttg cgcgaccgct gggtactggc ggtcgccggt
    13381 acccacggta aaaccacgac cgcaggcatg gcgacctgga tactggaagc gtgcgggtac
    13441 aaaccgggct tcgtgatcgg cggcgtaccg ggcaattttg aggtttccgc acgcctgggc
    13501 gagagcccat tctttgttat cgaagcggat gagtacgact gcgcgttctt tgataaacgt
    13561 tctaaatttg tgcattactg cccgcggacg ctgatcctca acaaccttga gtttgatcat
    13621 gccgacatct tcgacgatct gaaagcgatc cagaagcagt tccaccacct ggtgcgcatc
    13681 gtgccggggc aggggcgcat catctggccg gaaaacgaca tcaacctgaa acagaccatg
    13741 gcgctgggct gctggagcga gcaggagctg gtgggcgagc agggacactg gcaggcgaag
    13801 aagctgacta cggatacttc cgagtgggaa gtgtggctgg acggcgaaaa agtcggcgat
    13861 gtgaaatggg gcctggtcgg cgaacataac atgcacaacg gtctgatggc gattgccgcc
    13921 gcgcgccacg tgggcgtcgc gcccgcagaa gcagccagcg cgctggggtc atttattaac
    13981 gctcgccgcc gtctggagct acgcggtgaa gcgaacggcg tgacggtgta tgacgatttt
    14041 gctcaccatc ctacggcaat tctggccacg ctggcggcgc tgcgcggtaa agtgggcggc
    14101 accgcgcgca ttatcgcggt actggagccg cgttctaaca cgatgaagat ggggttatgc
    14161 aaggatgacc tggcgccgtc gttagggcgt gcggatgaag tgttcctgct gcagccgccg
    14221 catattccgt ggcaggtttc agaagtggcg gacgcctgcg tacagcctgc tcactggagt
    14281 ggagatgtcg atacgctggc ggatatggtg gtgaaaaccg cacagcctgg cgatcacatc
    14341 ctggtgatga gcaacggcgg tttcggcggc atccatcaga aattgctgga tgggctggcg
    14401 aaaaaagcac tggttgtggg gtaaaaaatg cccggtggcg ctgcgcttac cgggcctaca
    14461 atacgtacat tcccgtaggc cggataaggc gttagcgccg ccatccggca gacgctatca
    14521 acatgtaaaa ttacccttcg ttttccgcca gctcgcgcag atactggaag atctgacgcg
    14581 ctgatttcgg cggtttgttg ccttctttct ctttcttcgc attgcggatc aatgaacgaa
    14641 gctgttgacg atcggcgtgc ggccacaggg tcagtacttc ggctaccgcg tcatcgcctt
    14701 cgacgatcag acgatcgcgc agatgctcaa gcttgtgaaa cagcaccacc tgctgattat
    14761 ggcggttctt cagcttgtcc agcgcctggc gaataggttc aacgtcgcgt tggcgcagca
    14821 tttttccgat aagctgcaac tggcggcggc gtccttccat tttgattcgc tgggccagtt
    14881 caatggcgtc gcgcagatcg gcgtccagcg ggatcttatc cagcgcgttt ttccccagat
    14941 ccaccagttc cgcgcccagg cgttttaatt cctcggcatc gcgtttaatt tcacttttac
    15001 tgacccagat aatttcatcg tcttcgtctt cgatgtcatc accgggaacg tcgtcgagcc
    15061 agtcttcggg ctgctttgtc atgtcaggct ccttaaaaaa agaggctaat gttaccagtt
    15121 aagatgcgca ctgaaaaacg gttctctgtt agacttcaga gaaactctct ctacattatg
    15181 gcatttgcaa tgaaagtaat ctcacaagtt gaagcgcagc gtaagattct ggaagaagca
    15241 gtttcgacag cgctggagtt agcctcaggc aaatcggatg gggcggaagt cgccgtcagc
    15301 aagactaccg gcattagcgt cagcacccgt tatggtgaag tagagaatgt cgaatttaat
    15361 agcgacggcg cgctgggaat tacggtgtat caccagaacc gcaaaggcag cgcctcttcg
    15421 acggatttaa gcccgcaggc gattgcccgt accgtgcagg ccgcgctgga tatcgcgcgt
    15481 tacacgtcgc cggacccgtg cgcaggcgtg gcggacaaag aactgctggc gtttgacgcg
    15541 ccggatctgg atttgttcca cccggcagag gttacgccag acgaagccat tgaactggcc
    15601 gcgcgtgcgg aacaggcttc tctaaaggcg gataaacgca tcaccaatac cgaaggcggt
    15661 agctttaaca gccattacgg cattaaagtg ttcggcaaca gccacggtat gttgcaggga
    15721 tattgctcca cgcgccattc gctctcaagc tgcgtcatcg ccgaagagaa cggcgatatg
    15781 gagcgtgatt acgcttacac catcggccgg gcaatggcgg atctgcaagc gccggaatgg
    15841 gtcggggccg agtgcgcgcg ccgtacctta tcccgcctgt cgccgcgcaa gctctccacc
    15901 atgaaagcgc cggtcatttt cgccaatgaa gtggcgacag ggctatttgg tcatctggtc
    15961 ggggcgattg ccggcggcgc ggtataccgt aaatccactt ttctgctcga ctcgctgggc
    16021 aaacaaattc tgccggaatg gttaaccatc gaagaacacc cgcatctgct aaaagggctg
    16081 gcgtcttcac cgttcgacag cgaaggcgtg cgtacggagc gccgggacat tgtgaaggat
    16141 ggcgtactga cgcaatggtt gctgaccaac tattccgccc gcaaactggg gctgaaaagt
    16201 accggtcatg ctggcggcat tcataactgg cgtatcgccg ggcaggggct gaactttgag
    16261 cagttactga aagagatggg taccggcctg gtggtgacgg aactgatggg ccagggcgtc
    16321 agcggtatta ccggcgacta ctcccgcggc gctgcgggat tctgggttga aaatggtgaa
    16381 atccagtacc cggtaagtga aattaccatt gccggtaatt taaaagagat gtggcgtaat
    16441 attgtcaccg taggcgatga tattgaaacg cgcagtaata tacaatgtgg ttcggtattg
    16501 ttaccggaga tgaaaatcgc cggacaataa tacccgtcat acttcaggct gcaggcgcgt
    16561 tggctgcctg caactcgaat tattcagggt attacactta tcgttaataa taaaaaggaa
    16621 gtgagcaatg cgtaaaagcc tgttagctat tcttgctgtg tcatcgctgg tattcggttc
    16681 ggctgttttt gctgccgatc ttgaagataa tatggatatt ctcaatgata acctgaaagt
    16741 tgttgagaaa acggatagtg cccctgagct gaaagcggca ttaactaaaa tgcgcgcggc
    16801 cgcgctggat gctcaaaaag ctacgccgcc aaagctggaa gataaagcgc cggatagccc
    16861 ggaaatgaag gattttcgtc acggttttga cattctggtc ggccaaattg atggcgcgct
    16921 gaagctggcg aacgaaggta acgttaaaga agcgaaagcg gcggcggaag cgctaaaaac
    16981 cacccgcaat acgtatcata agaagtatcg ttaatttttg tgggatggcg gcttcgcttt
    17041 atccgcaggt cgccatccgg caaaatgtaa tacccatcac actttctcac tttatacgac
    17101 aacgtcattg tttcgccatt tcctctttat gccgcgatag atctcacact ttcccggcga
    17161 taattcatca atgccgcttt ttctgtggcg cagatcacct atcccactcg cgtttccact
    17221 tcgaggtgga aaataactcg ctacaaactt ttaaccctta ccgctagttt tatctcattg
    17281 ccattaatgg ggtgagacgc gtggataacg gagcagtaaa acacgatgcc ggtgagcgaa
    17341 ttaacgaact ggctgaacag gtgttaacgc aggtggatgg cctgctgggg cgacatcaca
    17401 ttgtccccaa tgcggtacag acgcaaatgc tgacctcgca cgttcgcgcg atggcgcacc
    17461 ggtcaattac cggcgagcct ttaccggaag tcgatgccag cttgtttgat gaaatctcag
    17521 ccgaatcaat ggcgctcgcc cgcgaaatcg tggcggcgtt tggcaacctt cctgacgaag
    17581 aagcctggct attatcggta cattttgaag tcgcgaaaga caacctctaa ggagcaaaaa
    17641 atggaacaga ttaccgtcgt gattggcgat cgcctgggta aaggccagaa agtggcggca
    17701 ggcgtggaaa aagcgggcgg tcgcgcggtc gtcgtaccgg gcgtcgcggc agacatgaag
    17761 ctgggcgatg tgatgaaagc ggaaaacgcc accttcggca tttcattttg cggcagcggc
    17821 ggcgcgggcg ctatcaccgc gcaaaacaag catggctaca aagccaaata tgggatgcgg
    17881 tcagtagatg aaggagtcac cgctatcaat gagggctgca acgtgttggg tttcggcttt
    17941 atggataaag aagagctcgg cgagcgcctg gtgcaggcgt ggcaaaagaa atacggcgcc
    18001 tgatgatgaa agagcaattc accaccacgg tgagagtaaa aggcaagggc gacgccaaag
    18061 cacgcgcctt tgccgatgcg ctgaaccatg ttcagtcggc ggtgatgaga gagtcgccgt
    18121 atatcttact gcgtattgag ccacaggatg tgcggattgt tcaggcgcat gagtcggtgc
    18181 gtaaagaggc ctttctgttt ttctttttgc gccgggaacg acgcacttac agcgtggagc
    18241 tggatgtggc cgtcaacgtg accgccatca atctcgacag ggtggatttc gtcgcgaaac
    18301 gctgattttt attaaaaagg catagttatg ttcctgataa tactaattaa atctctcatt
    18361 atcggcgcgc tggtcggcgt aggggtgggc gctggggctg cacgtatgtt tcacgcgcca
    18421 accacgcagg ggatgggcgc gttccgtacg ttgggcgaac tcaactcttg tgaaggcgac
    18481 ccggcatctc acttctcctt tggactgggt ttcttcttta acgcctgggc gtcgtctgtg
    18541 gcggccggat cgttcaccca ggatgtcgat caccgcatca tccctaactg gggcgcggcg
    18601 gcgctaatga tcaaaaaccg taacgtcggc gagacgctgc acgacccgaa aaaaatggcg
    18661 atcgcctgcg ccgtcatcgg catgatcgtc gtgacgttcc ttaacctgac cgcctcatcc
    18721 gtgccagaag cgctacaggt gacggcggtt aaggtgctgg taccggcggc aaacctgctg
    18781 gtcaacatcg tcatgcctgt gattttctgg ttagcggcga tcgacgctgg taaaaaatcg
    18841 ggtttctggg ccaccgtttt cggcggcgcg gcgcagctca tcatggggaa cgccgtaccg
    18901 gggctggtgc tgggtatttt gatcggcaaa ggcgtagaag agagcggctg gaaccatgtc
    18961 accaaagtga tgatggttgc catcgttttg ctgtttgtgt tgagcggttt cttccgcggc
    19021 ttcgacatga aaatgatcga gtctttcaac atgacggtac cgaactggct tgaactgatc
    19081 cacaactcgc tcagcggcaa ataacggaga ccacaatgga agagaataaa ggtttttggt
    19141 atgccgactg gtcgttcccg atctttgttg gcctgctctc ctccggcgtt ttcgccggga
    19201 cgcatatgta ctatctgtac ggtatcggcg catttaacga agtcgctttt gtggcgatgt
    19261 tgaaagcggg gatggatacc ggcgtctacg gcgcggtcgc cgctttcggc gccagctttt
    19321 tatttgcccg cattatcgaa ggttcgctgg tcgggattct ggatatcggc ggggcaattc
    19381 agactggcgt gggcttaggg gttccggcgt tactgctggg ggctggcttt gtcttcccgg
    19441 tggcgaactt tatcgcttcg ctgataaccg gtctggtgat tggcctggcg attggctaca
    19501 tcattattct ggcgcgtaag ttcactatta atcagagcga ctccacgtac ggggcggacg
    19561 tcatgatggg ggccggtaac acttcaggcc gttttctggg gccgttgatt atcctcagcg
    19621 ccatgacggc atcgattcct attggtctgg gctctctggt gggcgcgctg ctgttttata
    19681 tctggcagaa gccgattacc ggcggcgcga ttttaggcgc gatgatcctc ggttccatct
    19741 tcccggtttc gattagctaa ctgttgattt gtaggtcgga taaggcggtt gcgccgccat
    19801 ccggcaaagg agagaacgat gtttgattta ctcctgcgcc atgcgcgtct ggtcgatgac
    19861 acgctgacta atattgccct tcaggatggc aaaatcgcgg cgttgggtga cgttgatggt
    19921 ccggcgctga aaaccattga cctgcgcggc gaatgttacg ttagcgcggg ttggattgat
    19981 tctcacgttc actgctaccc gaaatcgccg atttaccacg acgaaccgga cagcgtgggt
    20041 attgccactg gcgttaccac agtggtggat gcaggcagca caggcgctga tgatattgac
    20101 gatttttaca cgctgactcg tgacgcggcc accgaggttt atgcgctgct gaatgtttca
    20161 cgcgttgggc ttattgccca aaacgagctg gctaacatgg ccaatattga cgctgatgcg
    20221 gttcggcagg cggtaaaacg ccatccggat tttatcgtcg gcctcaaggc gcggatgagc
    20281 agcagcgtgg taggcgttaa cggcatcacg ccgctggaac gcgctaaagc catgcagcaa
    20341 gaaaacggca acctgccgct gatggtacat attggcaata acccgccgga tctggacgaa
    20401 atagcggagc gtctgacggc gggcgatatc attacccact gttacaacgg taagccgaac
    20461 cgtattcttc ggcctgacgg cgagctgcgc gcctcggtga cacgagcgct ggcgcgcggc
    20521 gtgcgtctgg acgtcgggca tggtaccgcc agcctgagct ttgcggtggc taaacgcgct
    20581 attagcctgg ggattttacc gcataccatc agttccgata tctactgccg taaccgcatc
    20641 aacggcccgg tacattcgct ggctaatgtg atgtcgaaat tcctcgccat cggcatgtcg
    20701 ctgccgcagg tcattgcgtg cgtgacggcc aatgccgccg atagcctgaa tctgaaaacc
    20761 aaaggacgtc ttcagccagg tctggatgcc gacctgaccc tctttacgct taaacgccag
    20821 cccaccgtgt tggtagacgc ggaaaacgac agcttacagg ctgaagaatt gctgacgccg
    20881 cttgccgcga tacgcgcagg caagggctat atgaccgaac aagggagcgc ggaacatgcc
    20941 ttcgattttt gagaagtatc aattaaaaca ggtgattaac gcctccggac gtatgacggc
    21001 gctcggcgtc tccacaccgc gcccggaagt gatagacgcg gcgatggccg gaatgaatca
    21061 gtatttcgag atgaaagatc tggtgaataa aaccggtgag tacattgcga aattgctgga
    21121 agtggaaggg gcgacggtag tctcctgcgc cagtgcgggc cttgcccagt cggttgccgc
    21181 ggtactggtt caggacagcg actggctgct ggaaaacctg cacgttacac cgattgaaaa
    21241 taacgaaatc gtcctgccaa agggccacaa cgtcaacttt ggcgcgccgg tgggaacgat
    21301 ggtggcgctg ggcggcggca aactggtgga agccggttac gccaacgaat gttccgccgc
    21361 ccagttggcg gcggccatta cgccgcgcac ggcggctatt ctctatatca aatctcacca
    21421 ctgcgtacag aaaagtatgc tcagcgtgga gcaggctgcg gtggtggcgc gcacgcataa
    21481 tctgccgctg attgtggaca cggcggcgga agaagatttg cagtgctact accgcgtggg
    21541 cgcagatctc gttatctata gcggcgcaaa agcgattgaa gggccgacca gcgggctggt
    21601 gattggcaaa acacagtatg ttgagtgggt aaaacgtcag tcagcgggca ttggccgggc
    21661 gatgaaggtc ggcaaagagg gaattgttgg cctgacctgc gccattgaat tgtacctgcg
    21721 ggcgcaaaaa gagagcggcg cggagatggt agaaaaaatg gcgcccttta tcgacacgtt
    21781 gaacacgttt aacggcgtca gcgcccgcgt ggtgtgggac agcgccggac gcgatatcgc
    21841 gcgcacggaa attaagtttg atgaagccgt taccggcatc gccacaggcg acctggtcga
    21901 cgcgctgaag caaggggaat acgcgattta ctttcgcgga tacaaagcca acgaagggat
    21961 tattgaagcg gatgtccgca gcgtcgatcg cgcgcagtta gcgattgtgg cgcgtcgtat
    22021 tggcgaggtg attaatcagg agaaacaagc atgaaactga cccctaactt ttaccgcgat
    22081 cgcgtttgcc tgaacgtact ggccggttcg aaagataacg cccgggaaat ctacgcggcg
    22141 gcggaaggtc atgtgctggt tggcgtgctc tccaaaaact atccggatgt ggcaagcgca
    22201 gtcgcggata tgcgtgaata tgcggcgctt atcgacaatg cgctctccgt cggattgggg
    22261 gcaggcgatc ctaaccagtc ggcgatggtg agcgaaatct cgcgtcaggt acagccgcag
    22321 catgtcaacc aggtgtttac cggcgtaggg ggcagccggg cgctgctggg gcaaaacgag
    22381 acggtggtga acggtcttgt ctcgccgacc ggcacgccgg ggctggtgaa aatttccacc
    22441 ggcccgctaa gcagccgcgc gccggacggc atcgtaccca tagaaacggc gattgcgcta
    22501 ctcaaagaca tgggcggcag ctctgttaaa tactttccga tgggaggact cacctgtcgc
    22561 gacgagtata aagcggtggc tgacgcctgc gcccgccatg atttctggct ggaaccgacg
    22621 ggcggtatcg atctggaaaa cttcgccgag attctgcaca tcgcccttga tgcaggtgta
    22681 agcaaaatca ttcctcacat ttatagttcg attattgata aggtgagcgg caacacccgt
    22741 gcggacgatg tgcgtcagtt actcgctatc gtccggtcgc gtgtcggcta atcatgagga
    22801 gagagacgtg cgattcccca accaacgttt agcgcagcta tttgcgatgc tgcaaaacga
    22861 gacgctgccg caggacgagc tggcgcagcg gttgtcggtc tccacgcgta ccgttcgggc
    22921 ggatatcgcc gcgctgaaca tgttgctgac gccgcatggc gcgcaattta ctctcagtcg
    22981 cggcaacggg tatcaactca aaattgatga tccggcacgt tatcaatccc tgcaaacgca
    23041 gcaatctccc acgctggcgc gcggtccgcg caccagccag gagcggatcc actatttgct
    23101 ggcgcgtttt ttaacctccg ccttctcgct gaagctggag gatttagcag atgaatggtt
    23161 tgtcagccgt gcgacgttgc agaacgatat ggcggacgtg cgcgagcatt tgctgcgtta
    23221 tcatctgacg ctggaaacgc gtccgcgtca tggcatgaaa ttgtttggcg gagagatggc
    23281 gattcgcgcc tgtctgaccg accttttatg gacgctggtg cagcaggagc cctcccatcc
    23341 gttaattgtt agtaccacgc tgaacaccga ggtgtctcaa cggctgcagt ctcttttgcc
    23401 ggatattttc tctcattgtc aaatccgcct gaccgatgag ggcgagctgt ttctgcgttt
    23461 atactgcgcg gtggcggtac ggcgtattcg cgaggggtat ccgttatcgg aatgcgtggc
    23521 agaggaggtc gatgaaaagg tgcgccatgc ggcgcatgag attgcggagc tactacaaca
    23581 gctggctgac aagccgctgt cggagccgga agtaagctgg ctgaaggtgc atattgccgc
    23641 ccgccaggta caggagattg cccccagcgc cattaatgcc gatgatgaag aggcgctggt
    23701 gcactatatc ctcaatttta ttaataccca gtacaactat aacctgttga atgataaaca
    23761 gcttcacgcg gacttgctga cccacatcaa aacgatgatc acccgcgtgc gctaccagat
    23821 catgatcccc aacccactac tggaaaatat taagcagcac tatccgatgg cgtgggatat
    23881 gacgttggcg gcgatatcga gttggggaaa atacacgccg tataccatta gcgaaaacga
    23941 aatcggtttt ctggtgctgc atattggcgt tgggctggaa cgtagttaca acattggcta
    24001 ccagcggcag ccgcaggtac tgctggtgtg cgatgctggt aatgcgatgg tgcggatgat
    24061 tgaagcggta ctggcgcgga aatacccgca gattgagatt gcccgcactc tgacgctacg
    24121 cgactatgag gcgcgggaca gtatggtgga ggattttgtg atttccacag cgcggatcgg
    24181 cgaaaaagat aagccggtca tcatgatcgc gccctttcct accgactatc aattggagca
    24241 gatcggtaag ctggtgctgg tggacagaac ccgtccgtgg atgctggata aatatttcga
    24301 tgcctcgcat tttcgcatcg tggaggggga aataaatcaa cagacgctgt ttaaaacgct
    24361 gtgcgatcag ttgcacgagg aaggctttgt tgatgcggcg tttctcgatt cggttattga
    24421 acgtgaagct atcgtcagta cgttattagg cgacgggatt gccttgccac acgcgctggg
    24481 gctgctggcg aagaaaacgg tggtttatac ggtgctcgcg ccgcagggga ttgcctgggg
    24541 tgacgaaacg gcgcacgtta tttttttact cgccatcagc aaaagtgaat atgaagaggc
    24601 gatggccatc tacgatattt tcgtcacttt cctgcgcgaa cgcgccatga cgcgcctctg
    24661 cgcatgtcag aattttacgc aatttaaaac ggtcgcaatg gagtgtgtga gtcgcttttg
    24721 agaggcgtta tccagaattc gatgtaatgc gaatgtaatg ctaaactgca ttacacattc
    24781 gattctcctg gaggcataat ggccacgctg aacgtccgtc tggatgacaa actcaaaaat
    24841 gaggcttatg ccgtgctgga aaaactgaac attactccaa cggaagccgt gcgattactg
    24901 ttccagtacg tcgcggaaac ggggcgcatg ccagtgaaaa ccgtcactct tagcgacagt
    24961 gaagatgcac tgattcagac agttcgggag aggctgtcta gtccgcaaaa gggaatcaag
    25021 gttagtctgg atgacttatg aactggaatt cgacccgagg gccttaaaag agtggcataa
    25081 gctgggcgat acggtgaagg ctcagcttaa gaaaaagttg gctgatgtgc tattgaaccc
    25141 cagaatcgac tctgcccgtt taaacggtct tcctgactgc tataaaatta agcttaaatc
    25201 gtccggttat cgtctggtgt accaggttcg ggatgacgtt gtgattgtgt ttgttgttgc
    25261 ggtcggcaag cgagaacatt cagccgtcta tcacgatgca aacaaacggc tttagcgatc
    25321 aacgcaaatg atgcactact tggttgctgc taccgcgcca gataagcgcc gggtctttca
    25381 gatcctgcac aaatttgcca tcgaccagca cgttgatgag attgaccacc tgcatctgtg
    25441 cggcgttgag ttcatcgagc ctgtagccgg tccacaccca gatatctttc cccgggcact
    25501 ccgcgtggat gcgttgtacc agtgccagga tatccggtac gttttgcgga tgcagcggat
    25561 cgccgcccga cagcgagatc ccctgacggt gaatgcgcgt gtcgttcaga tcggcaatga
    25621 tcttatcttc catctctttg gtaaacggct ggccggaatt gagccgccag gtgcttttgt
    25681 tatagcagcc agggcattca tgcacgcacc ctgacacaaa cagggtgcag cgggtaccgg
    25741 ggccgttaac gatgtcgacg ggatagtatt gatggtagcg catagcgggt gtccagaaag
    25801 catgtaggcc ggataaggtg cttgcaccgc atccggcaac attgtgatgc ctgatgacga
    25861 cgcgattgcg tcttatcagg cctacggtct ttgcaaacgg aaattaacct atctgcccgt
    25921 tgcctaaatg cttcacgcgg cgcttcactt cttcctgctt accggcgtta aacggacgcg
    25981 cgtccgggct gcctaaataa ccgcacacgc gacgggtaac cgagacgcgc gcggcgtcgt
    26041 ggttgccgca tttcgggcag gtgaaacctt tactggtaca ttcgaactcg ccggtaaagc
    26101 cgcactcgta gcattcatcg atcggcgtgt tggtgccgta atacggtaca tgctgatagc
    26161 tgtaatccca gacatcttcc agcgctttca ggttgtgctg aatgttcggg tattcgccgt
    26221 agcaaatgaa acccccgttc gccagcggcg gatacggcgc ttcgaaactg attttgtcgt
    26281 acgggttgac cttcttctcc acgtcgaggt ggaagctgtt ggtgtagtaa cctttatcgg
    26341 ttacgcccgg caccacgccg aactcggcgg tatccagacg gcagaagcgg tcacagaggt
    26401 tttcacttgg cgtgctgtac agactaaagc cgtagccggt ctcgtctttc cactgatcca
    26461 cggcctggcg cagacgctcc acaatcgcga tgcctttagc gcgaagttgc tcgctgtcgt
    26521 acaggtgttc gccgccgaac agcgcgttaa tggtttcatg gataccaatg tagcccagag
    26581 agatggacgc acgaccattt ttaaagattt cagacacgtc gtcgtccgct ttcagccgca
    26641 cgccgcaggc gccttccata tacaggatag gcgcgacacg ggctttcacg ccttcaaggc
    26701 gggcgatacg ggtcatcagc gccttccgcg ccagcgccag acgttcatcc agcagtttcc
    26761 agaatgcggt ttcgtcgcct tttgcttcca gcgcgatgcg cggcaggtta aggctaatca
    26821 cgcccaagtt gttacgcccg tcgtggatct gctcgccgtt ttcgttctcc cacacgccga
    26881 ggaaactgcg gcagcccatt ggcgttttga acgaaccggt gactttgacc acctgatcgt
    26941 agttgagaat gtccggatac atgcgcttgc tcgcgcactc cagcgccagt tgtttaatgt
    27001 cgtagttcgg atcgccaaac ttgtggttca aaccatcgcg gatagcgaag accagttttg
    27061 ggaacacggc ggttttgcga tttttaccca gaccggcgat acggttacgc aaaatagacg
    27121 cctggatcag acgcgactcc caactggtgc cgaggccaaa accaaaggtc acgaaaggcg
    27181 tctggccgtt agcggtgtgc agcgtgttaa cttcgtattc cagcgactgg aaggcgtcgt
    27241 agcactcttt ttcggtgcga gaacgcgcat acccttcggc atccgggatc tgccactcat
    27301 cggcggtttt gcggtgcttg ttatagcttt cggtgacaaa cggcgccagc acttcgtcga
    27361 tacggttaat ggtggtgccg ccataaatat ggctggcgac ctgcgcgata atctgcgcgg
    27421 taacggcagt ggcggtagag atagattttg gcggttcgat ctcggcgtta cccatcttaa
    27481 agccctgggt caacatgcct ttcaggtcga tcaacataca gttgaacatc gggaagaacg
    27541 gcgaatagtc gagatcgtga tagtggatat cgccgcgctc atgcgcttgt actacgtcac
    27601 gcggcaacag gtgctggcgg gcatagtgtt tggcgacaat cccggccagc aaatcgcgct
    27661 gggtgggaat gactttactg tctttgttgg cgttttcatt gagcaacgcg gagttagttt
    27721 gctctaccag gccgcgaatt tcctggttca gacgaccacg cttttcacgc tgaatgtcac
    27781 gatcgtgacg gtattcgatg taggcgcggg caagctgttt gtacgggccg gacatcagtt
    27841 ggttttcaac cgcagtttgg atctcgttaa tatccacctg actgcgtgcg ttcatttggc
    27901 tgctaacgac ttctgcgacg gtggcacagt aatctgcgtc atcgactccc gctgctttag
    27961 ctgcacgtag aatggcttcc ttaatgcgct ctgatttgaa tggcacttta cagccatctc
    28021 gtttcatcac atgcggtgtc atgatcactc catatttgta agaacaggtt atccacagag
    28081 gccggggaag ccataacagg tttattcatc tcttttccaa tgacttcccg caatcctgac
    28141 ccaggttatc cacaattcac cttgtgtcga gtgaacaggt gttgtagcaa ttgtagtcaa
    28201 ttaatacaac atattgggtc ggcgtgcatt ttaaagtcta tatgtagtga tttgcatcaa
    28261 ggatgtttgc aattttattg atgtagaaca aggtaaaaat cagagcgtac agatggcggg
    28321 cgctgtagcg tttgtaaaag atagcaagaa aaatctgatt aattattcaa caaaaacaga
    28381 cagtaacctg gagcaacgcc acagcccgtg tcaataggtt tgtggcgttt atccgtataa
    28441 ggacgtcgcg ttagcgttgt aaccaccaga tggcttcaaa tgggcggagc gtcatcgcgg
    28501 ctggctggct ggcgacctcg ccataattat gcagtagcgc ctgccactgt cctttgatat
    28561 gcggtggatg ccactcctga cactggtcgc tcagattggc gacaaccagc agggtttgcc
    28621 cctgccactg gcgacgataa caccatactg atgggctacc cgggaggaga tcctgataat
    28681 cgccccagat cattacaggc tgggttttac gtagcgcaat cagcttttga taggtgtaaa
    28741 acaccgagtt ttcatcgcgt aatgccgccg cgacattaac ctccgtatag ttatcgcaca
    28801 ggcttatcca cggctcgccc tgggtgaaac cggcgttttt accgttgtcc cactgcatcg
    28861 gcgtgcggct gttgtcgcgg gatttactgg ccaggatagc cagtagttcg tcggggtcgc
    28921 gtccggcggc gcgtagcgcg gcaaacatgt tatggctttc cacgtcgcga taatcggtga
    28981 tgcgggtaaa gtgtgggttg gtcatgccga tttcttcgcc ctgatagata taaggcgtcc
    29041 cttgcatacc gtgcagcgcc atcgccagca ttttcgcggc tggaacccgg tattcaccct
    29101 cgtcgccaaa gcgggaaacg atgcgcggct gatcgtgatt acaccagaat aacgcgttcc
    29161 aggcgacgtt atgcatcccc tgttgccatt ggcggaacaa cgctttcagc gccacataat
    29221 caggttttgc cagcgtccac ttttcgccat tggggtaatc caccttcaga tgatgaaaat
    29281 tgaaggtcat cgagagttcg tcgccgctaa gcgcggcata ttgctggcag ttttccagcg
    29341 tggtagagga catttcgcct accgtcatca gattacgcgg cgtaaaaacg tcacggttca
    29401 tttcgcgtaa aaacgtatgc gtgcgcggtc cgtcggtata aaagcggcgt ccgtcgcccg
    29461 tcggatcgtc aggaaaatcc tgatctttgg cgatcaggtt caccacgtcc agacgcaggc
    29521 catccacgcc gcgatcggcc cagaattcgc agaccttttt cagctcggcg cgcacggcgg
    29581 ggttttccca gttcaggtcg gcctgttcag gcgcgaaaag gtgtaaataa tattgttcgc
    29641 tctggctatg ccagcgccag gcgctgccgc caaatttgga ttgccagtta ttcgggcaga
    29701 catccggcgt gccgtcgcgc cagatgtaaa actgacggta tgggctctct ttgttcagcg
    29761 cttcgcgaaa ccaggcgtgc tgggtagaag tatggttaaa caccatatcc aggatgatgc
    29821 gaatgccgcg tgctttcgcc tgcgcgacca gctcgtcaaa atcatccagc gtgccgtagg
    29881 tcgggtcgat agccgtataa tttgcgacgt cataaccgtt atccacctgt ggcgagatat
    29941 aaaacggcgt gagccagatg gcgtccacgc cgagtcgctg tagatagtca aggcgctgcg
    30001 tgacgccgcg taaatcgccg gtgccgctgc cggtcgtgtc ctgaaaactt ttcgggtaga
    30061 tctgataaat aacgccgttt tgccaccaga ggggaatagt cattgtagtt tcctgcaagt
    30121 acgttgggac gcaactgcgc cccgaagaag aattagacaa tttgtaatgt gccctgacga
    30181 tgcttacgct gatagataaa ggtggtcaga atcaccggga taacgatcgc gataaccatc
    30241 gccatcgcaa acacctgcca gtaagtcggc tggatagaga gaatgcccgg caggccgcca
    30301 acgccgatgc cgtttgccat tacgccattc agaccacaga gcagaccggc aaggccagag
    30361 ccgatcatcg cgcacagcat cgggaagcga tatttgatgt tgatgctgta cattgccggt
    30421 tcggccaccc ccagataggc ggagatcgcc gccggaacgg aaatttcacg ttcattgtgt
    30481 ttacggctgg agatgataat gcccaccacg gcggaggctt gcgcgatatt cgacagcgca
    30541 atcagcggcc agactggcgt accgcccatg ctctgaacca tctgcatatc gatagcgagc
    30601 gtggtctggt ggacgccggt aatgaccaac ggggcataca ggaagccgaa cagcgccgcg
    30661 cctatcgggg cgaaactgcc ggtcatcaga taacgtaccg caaaggccac gccgtcgccg
    30721 atcatgcgac caaaggggcc gataaaggcg tgggcgagaa agacggccag tatcaacgaa
    30781 cacaccggga cgacgaccag gtagagataa tccggcacga tgcgtttcaa ccgcgtttca
    30841 ataaatccaa gcgccagtcc tgccagtagc gccgggataa cctgcgcctg gtagcctatt
    30901 ttctcaatac taaatacgcc gaagttccag acgtccggcg tttgctggcc cagcagatac
    30961 gcattcatca actgcggcga caccagcgtc acgccgagca cgataccaag aatcggcgtg
    31021 ccgcccattt ttttcaccgc cgaccagcag atccccaccg gcagatagaa aaagatcgct
    31081 tcgccgatca accataaaaa atcataaagc gtttttagcg ccggatgcat ctgcgccagt
    31141 gtttgaccgt ggctcatcgg cacatcgccg atcacgttac gaaagcctaa gatcaaaccg
    31201 ccgctgatca atgccggtag tagcggaaag aagatctccg cgaagtggga aattaactgc
    31261 tcatgccact tcatgttctg gcgagcggct ttttttgcct gctctttatc agcatacgct
    31321 ttgccggtgg tctccagcag cgcgttatag taatcgccga cttcggtgcc gatcaccacc
    31381 tgaaactgcc cggcgttggt gaaacagcct ttaaccatcg gcaattgttc gatctctttt
    31441 ggtcgggcgt tcgcgggctg gtggagcaca aagcgcaggc gagtaatgca gtggctcacc
    31501 gtggcgatgt tgtcgcgccc gccaaccagg tcaatcagcc ggtcgatatc ggcttgtttt
    31561 actttgctca tcgtaaagcc tcatggcaga ggaggtaagt tatgggttgg cgcaagagta
    31621 gctcttcaac gttggtttaa aaatgggaac gttcccgaaa cgcggcgacg atcacaaatt
    31681 acgcatggta ttccgtttaa tcagccactc aggcgagggt agaaggaatg acgatccggc
    31741 gcggatcgca gcggccattg atctgttcga tcagctgcaa agccgcctgc cgtccggctt
    31801 cagcatagcc aggatcgaca gtgacgatct ccggatgcag gaattttatc agcggcgtat
    31861 tcccgatgct tgccagttgc agcgtctcaa tacgttgctc ctgtaaatac ttactggcgc
    31921 ccaacgccag cgtatcggtg gcgcagacta acgcggtggt atccggcatg atgacacttg
    31981 ccgtatgctc atagccctgc ttcatggcaa gaccgggaag ggcggcgacg ggatgaagtt
    32041 tatgtttttt gcaaaacgcc aggtatgcgt catgccgacg tttgccggtg gtaatatcgc
    32101 tatgaggaac gcccagaaag ctaatgttgc ggtgtccctg ctcatacagc cgctgcataa
    32161 ggatatgaat cgcgccctcg tcgtcgtaac agacggaggc aaaaccttgc gcatctcttg
    32221 ccagcagcac cagcgaggct ttccaggggg cgatcaactc ttctgtgatg ccggtaaagc
    32281 caaacagcac cacgccatca atgttacgtc gcctgagcat gcccagatgt tccattacca
    32341 gcatcggcga gaactgactt tccatcataa tagggtcgta gccctgttca taaaacgcag
    32401 gcagcatggt ctgaaccgcg aggttttcag acaacgaatc aaggcgagtg acgataatag
    32461 cgaccacttt atcgctttgt ccccgcatcg cacgggcgga gcgggacgga gagaaaccgt
    32521 gttgattcat caccgcttcg acacgctcgc gggtacgttt gcttacgccg ctttcattgt
    32581 taagcacgcg ggaaacggtt gatttcccta cgccgctcag gcgggcaatg tctttgatag
    32641 tgagccggtt ttgcatcctg ttttcccgtg gcgtgacgct gatggtgata aaaagagtaa
    32701 ctttactcaa gcgaagggca atgggcaaag tctggtttat cgttggttta attacgtaac
    32761 ggtatgatac cgccataatt gccacaaaac ttatggattt atgcgtataa tccgcggcgc
    32821 aaattattta cttaccggag gcgacatgga ccctgaaccc acccctctcc cgcgatggag
    32881 aattttcctt ttccggtaag cctgcctctg ctgtcttacc ggtgtgtaag acagtgacac
    32941 aataacgtcc ctgtttttat ttaaacattg ctcatcgggc aaggctttgc cgcgcctgaa
    33001 gaattttctg cgcctgactt cggcgcggag ggattaccta tgctaaaaac cattacccgc
    33061 cagctttttg cccggcttaa tcgtcatttg ccttatcgtc tggttcaccg cgatccgctg
    33121 cccggcgcgc agaccgcggt aaacgcgact atcccgcctt cgctgagcga gcgctgtctg
    33181 aaaatcgcgg caatggagca ggagacgctc tggcgcgttt ttgatacgca cccggaggga
    33241 ttaaacgccg ccgaggtgac gcgtgcgcgt gaaaagcatg gcgaaaaccg ccttccggca
    33301 cagaaaccct cgccgtggtg ggtgcatctg tgggtatgtt atcgcaatcc tttcaacatt
    33361 ttactcacga ttcttggcgg catttcttat gccacggagg atctgtttgc cgcaggcgtt
    33421 atcgccctga tggtcggtat ctcaacgctg ctgaattttg tgcaggaagc gcgctcgacg
    33481 aaagcggcgg acgcgctaaa agcgatggtg agcaataccg ctaccgtact gcgggttatt
    33541 aatgaaaatg gcgaaaacgc ctggctggaa ttacccatcg atcaactggt gcccggcgat
    33601 attattaagc tggcggcggg ggatatgatc ccggcggatt tacggattat ccaggcgcgc
    33661 gatctgtttg tcgcccaggc gtcgctgacc ggcgaatctc tgccggtcga gaaagtcgcc
    33721 acgacgcgtg agccccggca aaataacccg cttgagtgcg acacgctgtg ctttatgggg
    33781 acgaacgtcg tgagcggaac ggcgcaggcc gtggtgatgg cgaccggcgc cgacacctgg
    33841 tttggtcaat tggcggggcg cgtgtcggaa caagataacg agcagaacgc tttccagaaa
    33901 ggaattagcc gcgtcagtat gttgctgatc cgctttatgc tggtcatggc gccggtagta
    33961 ctgattatta atggttacac gaaaggtgac tggtgggaag cggcgctatt tgcgctctcg
    34021 gtcgcggtag gactcacccc ggaaatgttg ccgatgatcg tcacctctac cctcgcgcgc
    34081 ggggcggtga agctctcgaa acagaaagtt atcgtgaagc accttgatgc gattcagaac
    34141 ttcggcgcga tggatattct gtgcaccgat aaaaccggca cattgacgca ggacaaaatt
    34201 atgctggaaa atcatacaga tatttccggt aagcccagcg agcatgtact gcattgcgcc
    34261 tggctgaaca gccattatca gaccggtcta aaaaatttac tggatacggc ggtcctggag
    34321 ggagtagacg aaaccgccgc gcgtcagctc tccggacgct ggcagaaaat cgatgagatt
    34381 ccgtttgatt ttgagcgtcg ccggatgtcg gtggtggtcg ccgaagattc gaatgtgcat
    34441 caactggtct gcaaaggcgc gctacaggag atcctgaacg tgtgtactca ggtgcgccac
    34501 aacggcgata ttgtgccgct ggacgacaat atgctgcgcc gggtgaaacg cgttaccgac
    34561 acgctgaacc gtcaggggct acgcgtggtc gccgtcgcga ccaaatacct gcctgcgcgt
    34621 gagggcgatt accaacgtat cgatgagtct gacctcattc tggaagggta tatcgctttt
    34681 ctcgatccgc cgaaagagac caccgcgccg gcgttgaaag cgctgaaggc gagcggaatt
    34741 acggtgaaaa ttctcaccgg cgacagcgag ctggtagcgg cgaaagtttg ccatgaggtt
    34801 gggctggatg cgggcgatgt cgttattggc agtgatattg aaggattaag cgacgacgcg
    34861 ctggcggcgc tggccgcccg tacgacgttg tttgcgcgtc tgacgccgat gcataaagag
    34921 cgcatcgtca ctttgctcaa acgcgagggg catgtggtcg gttttatggg cgacgggatt
    34981 aacgatgccc cggcgttgcg ggcagcggat attggtatct cggtagatgg cgcggtggac
    35041 atcgcccgtg aggcggccga tattatcctg ctggaaaaga gcctgatggt gctggaagaa
    35101 ggcgtcattg aaggtcgtcg tactttttct aatatgttga aatatatcaa gatgacggcc
    35161 agctcaaatt tcggtaacgt gtttagcgtg ctggtagcga gcgctttttt gccgttcctg
    35221 ccaatgctgc cgctgcactt gctgattcaa aacctgctgt acgatgtatc ccaggtggcg
    35281 attccgtttg ataatgtcga tgaagaacaa attcaaaagc cgcagcgctg gaatccggcg
    35341 gatttggggc gctttatggt ctttttcggt ccgatcagct cgattttcga cattttgacc
    35401 ttttgtctga tgtggtgggt atttcatgcg aatacgccag aaacgcaaac cttgttccag
    35461 tccggctggt ttgtggtggg attactatcg caaacgctga ttgtgcatat gatccgtacc
    35521 cgtcgtctgc cgtttattca aagtcgcgcc gcctggccgc tgatggcgat gacgttgttg
    35581 gtgatggtcg tgggagtttc gttgccgttt tcgccgctgg cgtcttacct gcagttgcag
    35641 gcgctgccgt taagctattt cccgtggctg attgctattc tggcgggcta tatgacgtta
    35701 acccagttag tgaaagggtt ttacagccga cgttatggct ggcagtaaac actttcgtcg
    35761 gggattcgcc agcgtgctta atccccgata tcgctaacca aaccagatgc ccgtaaagct
    35821 cgacaagttt aacgcgatcg gctttatctt taaatttcag ggcttattca agcaactgta
    35881 gaatgctata tgcaggcata aaaaagagga atgtccagct aagtttgtaa aatacattct
    35941 ctgcccccga gccagaacga gaggaggaga tgtcccaccg ctggatatgt tttgcggata
    36001 tgcgacgaaa gcggcgaata tagctaatgc aataaactaa gtaaggagga atcgctaagg
    36061 cggcagtggg tttaggaaac ataagggtaa gcaatatggc tgcgataatg aagcataaaa
    36121 agacgatctt cgcagtagat tctatctgtt ttaattcctg gcgtatgctt tcagcatgtt
    36181 tctcctgcca gcgacggagc gtgctgttgc taaatccata ttcttcgcat aacgccttat
    36241 tcggcacgcc gtttttagac tgttgcagaa aatcggcgat ttgctcctcg gtaaaacgcg
    36301 ctcttaccat tgccgcctct ccatggctgt tggtgccccg aaccgggcaa acttgcgccg
    36361 cccggcgagg atgacgtccg gcgcttagcg acgaacagcg atcgcttcaa tctcaatttt
    36421 cacgtctttc ggcagacggg caacttccac gcaggaacgc gccgggaagg tcgcgttgtg
    36481 ctcggtgaag aacgcttcgt aggtggcgtt gacggtcgcg aaatcgttca ggtctttcac
    36541 gaagacggtc gttttcacaa tgtcgcctac tttcaggcca gcggcttcca cgatagcttt
    36601 aacgttttcc agcgactgac gtgcctgagc ggatacgtct tccgctacgg cgccggtttt
    36661 cggatcgacc ggaatctgac cggaagtgat taccatgcta cccaggtcta cgccctgtac
    36721 gtaagggccg attgctgctg gtgcattttc cgtcgcaata gttttgctca tgatttctcc
    36781 tgaattacag cggtaataga atgtccccgc tcattatagg gagccgggat ctcataacca
    36841 acccccatta gttggccagc accacattat gcgaaaactc tttttcacag tatttgcatt
    36901 tgagggcgat atcattggcg cgttttttca ctgcaaagct ggaggatacc ggttccgcgt
    36961 ggctgatgca gttgctgttc gggcaaacca gcacattatt aatacgctct ggcaggctgg
    37021 ggcgcgattt cccgaccacg tcgtagttgt cgatgcggtt aacggtggcc tgcggcgcgt
    37081 acagagcaag ttggttaacc tgctcatcgg tgaggaaggt gttttctatt ttgattaagt
    37141 ctttacgccc catctcgcca gacgggagat tcagaccgat agtgattcgc tgatcggtct
    37201 cggtcaattt aaacagactc agcagtttaa agcctacctg cgcagggata tggtcaatca
    37261 cggtgccgca tttaatggct tcaacctgca gtttgttatc gtgtgtcatc gcttttctcc
    37321 cttacagact cagttcgcta ttcagtacca acgccagtaa cgcctggcga gcgaaaatac
    37381 cgttgcccgc ctgttggaag taccaggcgt gtggcgtttt atccacatcc gtggtgattt
    37441 catcaatcct cggcagcggg tgcagcactt tcatattttc acgcgcgccg ttcaggtcgc
    37501 tggcgcgcag aacaaactgc gccttcacat tggcgtactc cgacgggtcg agacgctctt
    37561 tctgtacgcg agtcatatag aggatgtcga cgtcggccat gacctcttca atagaaccat
    37621 gcaggctcca ggccatccct ttttcatcca gcatatccag aatgtactgc ggcatcgcca
    37681 gcgcgtccgg cgcgataaaa taaaaacggt tgccgctaaa tttcgccagc gcctgggtta
    37741 gcgaatgcac ggtgcggcca tatttcagat cgccgaccat cgcgatatgc aggttatcca
    37801 gacggccctg cgtttcctgg atggtgaaca gatccaacag agtttgcgtc ggatgctgat
    37861 tcgaaccgtc gcccgcattg agcaccggca cctgaccgga aaactccgtc gccagacgtg
    37921 ccgcgccttc ttgcggatgg cgcatcacaa tcgcgtccac gtaagtgcta atcactgaga
    37981 tcgtgtcggc taacgtttct ccttttttcc ccagcgacgt gttggcgctg tcggagaagc
    38041 ccactacgct ggcgcccagg cgatgcattg aggtttcaaa cgacaggcgg gtacgcgtgg
    38101 aggcttcgaa aaagcagctg gcgatcactt tatgtttcaa aagctccggc tgcgggttgg
    38161 cttttaattt cgccgccgtc gccagtacca gattaagatc gtcgcggctg aggtcgttta
    38221 tggaaatgat atgtttttga tatagcgggt tagccatgtt tatctcctga cgcctgggca
    38281 aaaaaaagcc cctcaattga ggggcttggt attggttttc aacggaaaga aaaacggcag
    38341 gcctgcgtct tttttcagac gcggtaagac agaatgtcgt acacactgaa ccatgcttcc
    38401 tcccggcaaa ttgtccgcga ttatactcag ctctgttttg ggatcaagcg aattaatgca
    38461 tgatttactt gtcgcaaacg gttcttatga atttaaattc attttaagca aataattaat
    38521 ttgtttgtgt accagcgccg tgcgctgaac gacctgtggt gcgacccaga caatactgct
    38581 accggcaacg acgccgagaa tttccggcaa tgcgtggtaa tccagaattc tcgcgacggc
    38641 gcgaccataa cctgccgccg tatggataag gataaattcg ctattatgtt caacgctgac
    38701 gaccatttcg gctattgaac gtccggcatc cggcgaagga cgctgctggg gatttacgga
    38761 ataaatcttt tgtcctttcg catttctgat ttttattgcg cccagcagct tgagcaggcg
    38821 cgaaaccgta gactgactga taccttcaaa tccctcattt tgtaaatcgc ggcgaatctc
    38881 ctcctgggac aggtaacttt tttcactaat caggcgctga caaaccgcca gttgctgttg
    38941 ttctttggcg gagtaatcat cgtattcctt cataaatgca ccttatcttt attattgata
    39001 tcaacggact ggcgaaattc atcacatttg tcacattgat tgcggatcaa tcgggcggtt
    39061 ttgcaggaaa atgagaagct gatcaaaaaa ggtgacggcg tgcctgatgg cgctgtgctt
    39121 atcagtcctg tcggataaga cgcgtcgcca tctggctcgt tacatcatcg ctccgatgct
    39181 cagtaccgcc atattcagca atgtcaggat cagcaacagc ggcgcgaccc atttcagata
    39241 gcgaacatag ggaacccgcg cgatcgccag accgcccatg accacggcgg aggtgggcgt
    39301 aaccaggttc acaatcccgg aggccgactg gtaggcggtt acgaccaaat cccgctgtac
    39361 gtgggcaaaa tccgctaacg gcgccataat gggcatcgtc aatacggcaa gaccggaaga
    39421 ggagggcacc aggaaggaga gcaatacttc cagccagtag gttacgttta tgaaaatggt
    39481 ggtagagagg ccggaaacca gactttccgc gctgtgcaaa atggtgtggg taatcatacc
    39541 gttatccatg accaccacaa tgccgcgcgc gataccaata attagcgcca cgccgagcaa
    39601 atcccgcgcg ccgtcgataa aggtactggt gaacgcttcc tcgcccatcc gcgttatcac
    39661 gccaacgata atcgccgccg ccagaaagac gccggagatt tccgccatcc accagccgag
    39721 aaccgccacg ccgtaaatca tcaccgcgaa agaggcggcg aagatcagca gcacccattt
    39781 ccgggtagcc gtaaactcca gcagtgtatt ggcgcgattg ccgaggaaat gggcgcggtt
    39841 ttccgccatt ttatccgcca cgatagaaag ctcaggatgg gcgcggactt tgcgcgcata
    39901 gcgcattacc caaaacacgc acagtacgta gccgacaatt aacagcagta cacgcatcag
    39961 catgccctgc gtaaaaggga tgccggcggc gttggcggca atgaccgtgg cgaaaggatt
    40021 aatggtcgaa ccgagcgtgc ctatccccgc gccgagcagt acggttgccg tcgccactaa
    40081 cggatcgaag cgggccgcca tcatgaccgg caccagcagc gtgtagaagg gcaacgactc
    40141 ctccgccatg ccatagatag tgccgcctgc ggcgaacagc gccatcagaa tggggatcat
    40201 ccactcatct ttgccgttga gtttgatagt tacccgttca ataccggcat caatcgcccc
    40261 cgttttattc accaccccca gaaagccgcc gataatcaag acaaacagcg cgacgtcaat
    40321 ggcgccggcg gtgtaggttt cgtggttata gaggccgtca atcggcgcca gtaaaacagc
    40381 ggtaatccct tgcggatgcg cgtccacggg ggcatacgtt cccgccaccg gcacctcttt
    40441 tcccagcgtg gcgttcatcg ccatttggta ttttcccgcc ggcacaatcc aggtcatcac
    40501 cgcgaccagg gcaataagaa taaacaggat ggtataagcg gtgggaaatt taaatttacc
    40561 catgatgttc tctcctgata tcacggatat gcgccgcgag ggcgcatatc ctgtgggatt
    40621 agtcgccgag cgtcgccacc atgaccgctt tgatggtgtg catccggttt tccgcttcat
    40681 cgaagaccat cgagcctgcg gactcgaaca cctcttccgt gacctccagt cctttcaggc
    40741 cgtaagccat ttcgatttcg cgtcccactt tggtgtgctc gttatggaag gcgggcaggc
    40801 agtgcataaa cttcacatca ggattaccgg tagcgtttac cacctgctgg ttgacctgat
    40861 atggcgtcat cagactgacg cgctccgccc aggcttcttt gggttctccc atcgagaccc
    40921 agacgtcggt atagaggaaa tccacaccgt gaacgccatc ttcaacgctc tccgttaagg
    40981 tgatacgagc gccggtaacg ctggcgattt cccggcactg cgcgaccagc gcggcatcag
    41041 gccagaagga ctttggcgct atcagacgga tatccatgcc catcttcgcc gcgcccacca
    41101 tcagcgaatt gcccatgttg ttgcgcgcgt cgcccaggta ggcgaagctc agttccggca
    41161 gcgttttgcc cggcgcatgt tccagcatgg tcatcagatc ggccaggatc tgtgtggggt
    41221 gaaattcatc ggtcaggccg ttccagacgg gaacgcccgc gtattccccc agctcttcca
    41281 caatgtgttg accaaatccg cgatattcga tgccgtcata catccgcccc aggacgcgag
    41341 cagtatcttt catggactct ttatggccga tctgcgagcc gcttgggccg agataagtca
    41401 cctgcgcgcc ctggtcgaac gcggcgactt caaacgcgca tcgggtgcga gtagaggttt
    41461 tttcaaaaat cagcgcgatg tttttgccga tcagtgtttg cttttcgcat ccggcttttt
    41521 ttgcggcttt cagctcaata gccagatcga tgaggtgttg gatttccgcc ggggtgtagt
    41581 caagcagctt caaaaagtta cgatttttca gtgaaataac cattacaata tccttgttaa
    41641 aatgaattgc ctgatggcgc tgcgcttatc cggcccacgg ttatgcgcgc tctgtaggcc
    41701 ggataaggcg gaagccgcca tccggtaaaa agccttatgc gtcaacgtcg gcggtttcac
    41761 accgaatcaa agtacctttc tcgcccgcga gaatggcttg cccatccgcc agcgagccga
    41821 ttccggcaat gccgcagcaa tggctgacaa actcagcgca ggcggtcact ttcgggccca
    41881 tcgaaccggc gtcgaactgc atttcacgaa gcagctccgg cgtaacctgc gccagcgggc
    41941 gttgggtggg tttgccccag tcgagataca ccgcgtcgac atcggtcaga atgagcagcg
    42001 cgtcggcgtg aatttggctg gcaagcaggg cggcggacag atctttgtcg atcaccgcct
    42061 cgataccgtg gtagccatcg gctttttcca cgaccggcac accgccgccg ccgttacaga
    42121 taaccaggtg atcgcggcta atcagcgcgc ggatggcatc gttttccaca atgcgtttcg
    42181 gctgcgagga gggcacaacg cggcggaagg cgttaccgtc ggctttgaat acccagccct
    42241 tttctgcctg taacgcacgg gcctgcgctt cgtcgtaaat ggggccgata tatttggttg
    42301 gattgaggaa tgccgggtcg ttggcatcga cttcgacctg ggtgagcagg acgctgattt
    42361 cacgctccgg cagatgattc ttcagcgcct gttgcagcat gtagccaatc atgccctggc
    42421 tttccgcacc gagaatatcg agcgggtagg gcgtaacgtt agcgtaggcg ctattttgta
    42481 gcgccagcag ccctatctgt gggccgttgc catgcactaa cactacgcgc cattgccggg
    42541 taagctgggc gatggttctg gccgccagtt cgatattttt acgctgaata tcagcctcca
    42601 gcggttcgcc gcgtttgagc agcgcattgc cgcccagcgc gacgaccagt gtgcgtttgt
    42661 tttccataac gtctccttta aataccatcg cgttccagtg gacagctcat gcagcgtgcg
    42721 cctccgcgcc cgcgacccag ttcatcgccg ggaatgggaa ggacggtaat gccggctttg
    42781 tcgtattttt cgttggtcca gatgttgcgc tcatagccca ccaccacgcc gggacgcagg
    42841 gtgagcacgt tattggcgtc attccactgt tcgcgctcag cttcaaatgc gtcgccgcca
    42901 gtggtgatta agcgcacctg atcgatgcca agcgctgttt caagagcatg aaccagcgtg
    42961 ctctcctggg ttcgtttcag accgccgcgt ccgtctggcg tcagcgtcca gcactgaacg
    43021 tccgggcgaa cgacttccgg atagacagag aaggtgtcga tatcaatgtg ggtcatgacg
    43081 gtgtcaaggt gcatgcagga gcgatgtttt ggcagttcaa cggcaatgac gcgttccgcc
    43141 tgacgatgtt taaacaatgc ctgcgccagg aactcgacac cctgcggcgt agtacgttca
    43201 gacataccga tcaacaccgc gccgcggcca atcaccagca catcgccgcc ctctaaagtg
    43261 gcgtggtcgt aattaatgtt ctcgtcgccg aaatatttaa tgaaatcacc gtctgcgaat
    43321 tgtggatgcc agcgataaat agcacgtaaa ttattcgttt cacgttggcg tgcaggtttc
    43381 gccatggggt taattgagac gccgttatat atccagcagg acgtgtcacg ggtaaatagg
    43441 tgattcggta atggcttcat aataaagtca ttaatatcgt gagtatcgac caccatattt
    43501 tttatggagg cggggatttc gccgtaagtt aaaccgccgc ttaaatggcg agccagttca
    43561 cggtgcggca tatccgccag ccaggcgcga atatctgcgg caaaggtggg cccaaggcga
    43621 taatcggaaa tttgcgtatc cagtagccag gctttagcgt cagccacatc cagtgtttgg
    43681 gtgagcaggt cggttaacag caacacttct atcccttgct ggcgcagcgt gttggcaaaa
    43741 atgtcatgct cttcgccagc gcgctctacg gataatacat cgtcaaaaag taattcctga
    43801 caatttgaag gggtaagtct ttttaggctg agattgggac gatgcaacat tacgctgcgt
    43861 aattgaccga tttcagaacc gacaaaatgc ttttccatca ttataccttt tacataattt
    43921 caagaataaa gaaggagtgg ctgcaaatat ttagcgtgct tgcagtcgcg gcgtttcagt
    43981 taaattcggg agcaatgatt gaattttatt tgggttgtta atgtgatgag attcacatca
    44041 attaaggagt gctatttttc ttactta
//
LOCUS       DAJVKX010000025        44045 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000025 DAJVKX010000000
VERSION     DAJVKX010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 44045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44045
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.025"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(14..1594)
                     /locus_tag="OPY25_001346"
     CDS             complement(14..1594)
                     /locus_tag="OPY25_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HCS0926997.1"
                     /translation="MNSTLIDSLLARRRAVSPWAGLYFLQSLLINLALGYPFSLLYTA
                     AFTCLLLLLWRYLPRGQKALLGICSLVAACYFPFGQAYGAPNFNTLLALHSTNMEESS
                     EILTIFPWYSYLTGLFIFALGIIALRRRKEEVRPRWNSLDSLCLLISVAAFFVAPVQN
                     LAWGGVFKVIDTGYPVFRFAKDVIVNNNEVIEEQHRMAQLSGIKDSWTVTAVKPRYHI
                     YVVVIGESARRDAMGAFGGHWDNTPFASHVNGDFFMDYIAASGSTQKSLGLTLNRVVD
                     NKPQYQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEAHFLKNGDFEADK
                     NTRDDALLTMTAQVLATERTQPQLIVLHLMGSHPQACDRTHGKYATFVQSKETSCYLY
                     TMTQTDDLLRQLYTQLRHSGDSFSLVYFSDHRLAFKERGKAVQYLAHDDKFQQNFQVP
                     FMVLSSDSKAHRIIKARRSANDFLSFFSQWTGISAKEIKNRYRFISEQKAGPVYITNF
                     KLQKVDYNHLGSDIFSLK"
     gene            complement(1860..1988)
                     /gene="mntS"
                     /locus_tag="OPY25_001347"
     CDS             complement(1860..1988)
                     /gene="mntS"
                     /locus_tag="OPY25_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HCS0926998.1"
                     /translation="MNEFKRCIRVFSHSPFKVRLMLLSMLCDMINGKPEQDNPSTK"
     gene            2174..2647
                     /gene="mntR"
                     /locus_tag="OPY25_001348"
     CDS             2174..2647
                     /gene="mntR"
                     /locus_tag="OPY25_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HCS0926999.1"
                     /translation="MGRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIIEVGEARQVDMAARLGVSQPTVAKMLKRLASLGFIQMIPWRGVFLTPEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE"
     gene            2644..3756
                     /locus_tag="OPY25_001349"
     CDS             2644..3756
                     /locus_tag="OPY25_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HCS0927000.1"
                     /translation="MNLAFLRALRRDRFFQLLIIVGMALSLFVPFAPRAWPGAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMTRRFHTERQLAMFLVLAAAALSTFLTNDVAL
                     FIVVPLTITLKKLCAIPVNRLIIFEALAVNAGSLLTPVGNPQNILLWGRSGLSFAEFS
                     GQMAPLAVMMMLTLLLLCWFCFPGRALQYHTGTRSPQWQPRLVWSCLALYVVFLTALE
                     LRQELWGLVLVAAGFIVLARRVIVSVDWTLLLVFMAMFIDVHLLTQLPALQGVFNQVG
                     ALSHLGLWLTAIGLSQVISNVPSTILLLNYVPASTLLAWAVNIGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHFYSLPMLAWAALVGYGLLQLMP"
     gene            complement(3800..4720)
                     /gene="ldtB"
                     /locus_tag="OPY25_001350"
     CDS             complement(3800..4720)
                     /gene="ldtB"
                     /locus_tag="OPY25_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HCS0927001.1"
                     /translation="MNMKLTTLFAAAFAVVGFCKTASAVTYPLPTDGSRLIGQNQVIT
                     VPEGNTQPLEYFAAEYQMGLSNMLEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGII
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNDDI
                     KFLFENVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGKEAVPITLNKS
                     ILAVTNEPDVDQTVVQQAVQDRSGMPVRLN"
     gene            4940..6535
                     /locus_tag="OPY25_001351"
     CDS             4940..6535
                     /locus_tag="OPY25_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HCS0927002.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFETFTVLDTVIMGHGELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPLEQHYGLMSEVAPGW
                     KLRVLLAQALFSNPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGDLRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEALTKGFDNGPL
                     FKNVNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLDADHGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRVIEI
                     TPERVVDFSGNYDDYLRSKGIES"
     gene            complement(6657..7922)
                     /locus_tag="OPY25_001352"
     CDS             complement(6657..7922)
                     /locus_tag="OPY25_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HCS0927003.1"
                     /translation="MTTPFTYETLPADPKAAIRQMKQALRAQIGDVQAVFDRLSATIA
                     ARVAEINDLKAQGQPVWPIIPFSELATGNISDATRAEVKRRGCAVIKGHFPREQALAW
                     DQSMLDYLDKNHFDEVYKGPGDNFFGTLSASRPEIYPVYWSQAQMQARQSEEMALAQS
                     FLNRLWQVERDGKRWFNPDISIIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQ
                     QVFASVFNGNVEQYDPWNAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYILLRPLLDDVPEDELCGVAPGRVLPISEQWHPLLMAALTSIPPLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYARKVKAALETGASPDDFP
                     REDYETTWEGRFTLRDLNIHGKRALGMDV"
     gene            8184..8993
                     /locus_tag="OPY25_001353"
     CDS             8184..8993
                     /locus_tag="OPY25_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCS0927004.1"
                     /translation="MTVNVVVTDMDGTFLDDAKQYDRVRFMAQYQELKKRNIEFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLKSAYVSKNAPETFVALMAKHYHRLQPVNDYHDIDDILFKFSLNLPDEQIPL
                     VIDKLHVSLDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWNRSPQNVVAIGDSGN
                     DAEMLKMAHYSFAMGNAADNIKALSRYHTDDNNHQGALNVIQAVLDGTDPF"
     gene            complement(9071..11503)
                     /locus_tag="OPY25_001354"
     CDS             complement(9071..11503)
                     /locus_tag="OPY25_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HCS0927005.1"
                     /translation="MTQLKLDTLSDRIKAHKTALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLAERTIWIKHDELIVGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFSVSEENKRILHDVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDDLRDKVAERRSRINLTVLEDLHGEQFLKAIDIVLDAVSQ
                     HITRFAALARQMAGEESRESRRKELLTIAENCEVIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIELLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLINGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEKALSAGNFNNFDEVMAAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGVIGQQQLAAALADDFDGLPHEQLRQRLINGAPKYGNDDDS
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAATMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTGSILGGVLLNQKLNPTTLENESDKQK
                     LMVLLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            complement(11509..12408)
                     /locus_tag="OPY25_001355"
     CDS             complement(11509..12408)
                     /locus_tag="OPY25_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HCS0927006.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARAQDL
                     LYDARLCLEGCDLCAQAAPDVIERALNGLLIHREKLTDAHFSILAHCCPTQALTVCGE
                     IKSVDEIMATVLRDKPFYDRSGGGLTLSGGEPFMQPELAAELFKASHDAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADGPFKQWTDGSASRVLENLRKLAAAGKKMVIR
                     VPLIQGFNADEETIKAITDFAADELHVGEIHFLPYHTLGINKYHLLSQPYHAPDKPLD
                     APALLDFAQKYACQKGLTATLRG"
     gene            complement(12686..13435)
                     /gene="moeB"
                     /locus_tag="OPY25_001356"
     CDS             complement(12686..13435)
                     /gene="moeB"
                     /locus_tag="OPY25_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HCS0927007.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFEGQEALKDARVLVVGLGGLGC
                     AATQYLAGAGVGQLTLLDFDTVSVSNLQRQTLHSDATVGQPKVESARDALARINPHIT
                     ITPVNARLDDDAMTSLIAGHSLVLDCTDNVSVRNQLNAGCYIAKVPLISGAAIRMEGQ
                     VTVFTYRENEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAHYGQP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(13435..14670)
                     /gene="moeA"
                     /locus_tag="OPY25_001357"
     CDS             complement(13435..14670)
                     /gene="moeA"
                     /locus_tag="OPY25_001357"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HCS0927008.1"
                     /translation="MEFSAGLMPLETALTQMLSRITPLTAVETLPLMNCFGRILATDI
                     VSPLDVPGFDNSAMDGYAVRVADLSADKPLPVAGKAFAGQPYQGEWPAGTCIRIMTGA
                     PVPAGCEAVVMQEQTEQTDDGVRFTTDVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAE
                     LPVLASLGIADAQVVRKVRVALFSTGDELQLPGQLLEAGQIYDTNRLTIHLMLQQLGC
                     EVINLGIIPDDPGKLRAAFVDADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVR
                     TTSRLKKTPGRLDFQRGILQRSANGELEVTTTGHQGSHIFSSFNLGNCFIVLERERGN
                     VEPGEWVEVEPFNALFGGL"
     gene            14874..15815
                     /gene="iaaA"
                     /locus_tag="OPY25_001358"
     CDS             14874..15815
                     /gene="iaaA"
                     /locus_tag="OPY25_001358"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCS0927009.1"
                     /translation="MNKAVIAIHGGAGAIARAQMSHEQELRYIQALSEIVESGQKMLE
                     AGDSALDVVTEAVRLLEACPLFNAGIGAVYTRDGTHELDACVMDGNTLKAGAVAGVSH
                     VRHPVLAARLVMERSPHVLMVGEGAENFAFSQGMARVSPDIFSTPARYEQLLAARAAG
                     EMALDHSGAPLDETKKMGTVGAVARDKFGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRTLAAYDIAALMEYGGLSLADACERVVMEKLPALGGSGG
                     LIAVDHEGNVALPFNSEGMYRAWGYAGDTPTTGIYRE"
     gene            15826..17697
                     /gene="gsiA"
                     /locus_tag="OPY25_001359"
     CDS             15826..17697
                     /gene="gsiA"
                     /locus_tag="OPY25_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HCS0927010.1"
                     /translation="MPHSDELDSRDVLSVSGLNIAFHHEGQQVDAVRNVSLRLKRGET
                     LTIVGESGSGKSVTALALMRLIEQSGANVRCGEMLLRRRNRQVIELSEQSDAQMRRVR
                     GADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEALAEAKRMLDQVRIPESQA
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQEM
                     SMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPTHPYTQTLLAAVPQLG
                     AMRGHSLPRRFPLISADEPALYESQIEQDTVVEGEPILQVRGLVTRFPLRSGLFNRVT
                     REVHAVENISFDLWPGETLSLVGESGSGKSTTGRALLRLVESRQGEIIFNGQRIDTLS
                     AGKLQPLRRDIQCIFQDPYASLDPRQTVGYSIMEPLRIHGLGQGDAAAKRVAWLLERV
                     GLRPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSVRGQIINLLLD
                     LQREMGIAYLFISHDMAVVERISHRVAVMYLGQIVEMGPRRAVFENPQHPYTRKLMAA
                     VPVADPSRHRPRRVLLSDDIPSNIHKRGEETPAVSLQLVGPGHYVARPLQDNALSRL"
     gene            17730..19268
                     /gene="gsiB"
                     /locus_tag="OPY25_001360"
     CDS             17730..19268
                     /gene="gsiB"
                     /locus_tag="OPY25_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HCS0927011.1"
                     /translation="MTQFITHKWLAALGLASSIAAFPALAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKDMKVKNVLAEGYTVSDDGLTYTITLRQGVKFQDGA
                     DFNAAAVKANLDRASNPDNHLKRYNLYKNIAKTEVVDPATVKITLKQPFSAFINILAH
                     PATAMISPQALEKYGKDIGFHPVGTGPYQLETWNQTDFVKVKKFAGYWQQGLPKLDSI
                     TWRPVTDNNTRAAMLQTGEAQFAFPIPYEQAALLAKNKNLELVASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRQALVKVAFAGYATPATGVVPPSIAYAQSYQPWPYDPAKA
                     RELLKEAGYPDGFSTTLWSSHNHSTAQKVLQFTQQQLAQIGIKARITAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTQFNTAFYSNKQVDSDLAA
                     ALKTNDPQEKTRLYKEAQDIIWKESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFDD
                     ADLK"
     gene            19329..20249
                     /gene="gsiC"
                     /locus_tag="OPY25_001361"
     CDS             19329..20249
                     /gene="gsiC"
                     /locus_tag="OPY25_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HCS0927012.1"
                     /translation="MLNYVLKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLIAGPEAD
                     AQVIALVRQQLGLDQPLHVQFWHYITHVLQGDFGTSMVSRRPVSEEIASRFLPTLWLT
                     ITSMIWAVLFGMAIGIAAAVWRNRWPDRVGMTLAVTGISFPAFALGMLLMQIFSVDLG
                     WLPTVGADSWQHYILPSLTLGAAVASVMARFTRSSFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVDMRDYPVIQA
                     EVLLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            20252..21163
                     /gene="gsiD"
                     /locus_tag="OPY25_001362"
     CDS             20252..21163
                     /gene="gsiD"
                     /locus_tag="OPY25_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HCS0927013.1"
                     /translation="MRLFNWRRQAILHAMPVVKPDQIRTPWREFWRRFRRQHVALVAG
                     GFVLALILVAIFARWLTPYDAENYFDYDSLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAIIGTVLGLLAGYYEGWWDRFIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIVAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDTTILFSHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVALFPA
                     VAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(21254..22579)
                     /gene="rimO"
                     /locus_tag="OPY25_001363"
     CDS             complement(21254..22579)
                     /gene="rimO"
                     /locus_tag="OPY25_001363"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HCS0927014.1"
                     /translation="MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPHYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLQHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGDVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPMKTS
                     MVSLCEQLSKLGVWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGAGANELPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIVDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDIVRVKVENADEYDLWGSRV"
     gene            22810..23193
                     /gene="bssR"
                     /locus_tag="OPY25_001364"
     CDS             22810..23193
                     /gene="bssR"
                     /locus_tag="OPY25_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HCS0927015.1"
                     /translation="MVVDRLRTDLLNKLINARIDLAAYLQLRKAKGYMSVSESDTLRD
                     NFFELNRELHDHALRQGLHLDQEEWNALRRAEGALAAAAVCLMSGHHDCPTFIAVNAD
                     KLENCLTTLTLSIQSLKAHSPLTQV"
     gene            23312..24433
                     /locus_tag="OPY25_001365"
     CDS             23312..24433
                     /locus_tag="OPY25_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="HCS0927016.1"
                     /translation="MRRILLAIVSFSLFSSWANANLAPVNVEVLQTRLDHPWSLAFLP
                     DNRGMLITLKGGQLRHWQTGRGLSDPLAGVPKVWANGQGGLLDVVLAPDFAQSRRVWL
                     SYAEADREGNAGTAAGFGRLSDDFQRLEHFRTVFRQMPKLSTGNHFGGRMVFDAQGFL
                     FIALGENNQRATAQDLDKLQGKLVRLTGQGEIPPDNPFVHQAGARPEIWSYGIRNPQG
                     LAINPWSGALWLHEHGPRGGDEINIPEKGKNYGWPLATWGVNYSGLKVPEAKGEIVEG
                     TEQPVYYWKDSPAISGMAFYASDVFAPWRHKLFIGALKDKEVIVMRVDGNTVTEEGRI
                     LGDRKQRIRDVRVGPDGYLYVLTDESDGQLLKVSPAATR"
     gene            complement(24430..25056)
                     /locus_tag="OPY25_001366"
     CDS             complement(24430..25056)
                     /locus_tag="OPY25_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HCS0927017.1"
                     /translation="MITLWGRNNSTNVKKVLWTLEELELPYDQILAGGKFGVNQDADY
                     LAMNPNGLVPLLKDDETDLLLWESNAIVRYLAAQYGQNRLWVDNPARRAEGEKWMDWA
                     NQTLSPAHRVILMGLVRTPPEKRDQAAIEAGIEKCDSLFALLDDALAHQPWFSGDNFG
                     TGDIAIAPFVYNLLNVGLKWTPRPNLQRWYQQLTERPAFRKVVMIPVT"
     gene            25300..26502
                     /gene="dacC"
                     /locus_tag="OPY25_001367"
     CDS             25300..26502
                     /gene="dacC"
                     /locus_tag="OPY25_001367"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HCS0927018.1"
                     /translation="MTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAK
                     RLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNIRQP
                     NRNRLLWSTNLHVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASF
                     TLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVEEGGFFSRMWDFVLMKLH
                     QWFGSWFS"
     gene            complement(26548..27306)
                     /gene="deoR"
                     /locus_tag="OPY25_001368"
     CDS             complement(26548..27306)
                     /gene="deoR"
                     /locus_tag="OPY25_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HCS0927019.1"
                     /translation="METRRDERIGQLLQALKRSDKLHLKEAATLLGVSEMTIRRDLNH
                     KSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAQLAAGLVQAHQTVFIDCGT
                     TTPWIIEAIDNDLPFTAVCYSLNTFLALQDKPHCRAILSGGEFHASNAIFKPLDFHET
                     LNNICPDIAFYSAAGVHTSKGATCFNLEELPVKHWAMTMAQSHVLVVDHSKFGKVRPA
                     RMGELSRFDTIISDRRPDEAFVAYAKAQQITLMY"
     gene            complement(27378..27986)
                     /gene="ybjG"
                     /locus_tag="OPY25_001369"
     CDS             complement(27378..27986)
                     /gene="ybjG"
                     /locus_tag="OPY25_001369"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCS0927020.1"
                     /translation="MLENLNNSLFYFINATPDSAQWIISLAIFIAKDVINIVPLLAVV
                     LWLWGPRDRVCAQRQLIVKIGIALIISLAVSWTMGHLFPHDRPFVDHIGYNFLHHAAD
                     DSFPSDHGTVIFTFALAFLFWHRLWSGIVMMAIAMTIAWSRVYLGVHWPLDMIGALLV
                     AMLGCLSAQLIWQWYGAPLYQALQRCYRFCFALPIRKGWVRD"
     gene            28299..29531
                     /locus_tag="OPY25_001370"
     CDS             28299..29531
                     /locus_tag="OPY25_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0927021.1"
                     /translation="MQNRLQSGGRLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGLDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLATLLA
                     KNIEQFTFLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWVHVLPWEGMFILFAALAAIAFFGLQRAMPETATRRGETLSFKALGRDYRLVIKN
                     RRFVAGALALGFVSLPLLAWIAQSPIIIISGEQLSSYEYGLLQVPVFGALIAGNLVLA
                     RLTSRRTVRSLIVMGGWPIVAGLIIAAAATVVSSHAYLWMTAGLSVYAFGIGLANAGL
                     VRLTLFSSDMSKGTVSAAMGMLQMLIFTVGIEVSKHAWLSGGNGLFSLFNLANGILWL
                     LLMLVFLKDKRTGNLQTV"
     gene            complement(29585..30400)
                     /locus_tag="OPY25_001371"
     CDS             complement(29585..30400)
                     /locus_tag="OPY25_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCS0927022.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRDRFMAQYQQMKRQGIRFVVAS
                     GNQYYQLISFFPEIAHEIAFVAENGGWVVSEGEDVFNGELAKADFQAVVEHLLTRADV
                     EIIACGKNSAYTLKRYDDALKAVAAMYYHRLEFVDNFNNISDVFFKFGLNITDERIPE
                     VQAALHDAIGDIMVPVHTGYGSIDLIIPGVHKANGLRLLQQRWGIHDSEVVVFGDGGN
                     DIEMLRQAGFSFAMSHASEAVAAAAKYRAGSNNQEGVLDIIDSVLNNEPPFNV"
     gene            complement(30397..31608)
                     /locus_tag="OPY25_001372"
     CDS             complement(30397..31608)
                     /locus_tag="OPY25_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0927023.1"
                     /translation="MTVLSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     STAEMGTVLFGLSIGSMSGILCSAWLVKRFGTRKVIHTTMTCAVTGMVILSVALWCAS
                     PLIFALGLAVFGASFGAAEVAINVEGAAVERELNKTVLPMMHGFYSFGTLAGAGVGMA
                     LTALSVPANIHIILAAAVAIAPIFIAIRAIPDGTGKNASEGSHLQEKGLPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVTVVRASALMGALGIGLIIFVDSDWVAGVSVILWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMMVVLALVILAALVAKAVAKPV
                     STPQPVMEHNA"
     gene            31776..32396
                     /locus_tag="OPY25_001373"
     CDS             31776..32396
                     /locus_tag="OPY25_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCS0927024.1"
                     /translation="MKENAVRRANDPKRREKIIQATLEAVKTYGVHAVTHRKIAAIAQ
                     VPLGSMTYYFAGMDALLSEAFTLFTENMSRQYQDFFAQVTDVEGACQAITEMIYGSQV
                     TTPDNMALMYQLYAYASDKPALKIVMQNWMQRSQNTLAQWFDAQTARALDAFIEGMTL
                     HFVTDRTPLAREAILQMVKRIAGESMSCHSASGNKKPTNLEPKWRG"
     gene            complement(32513..34198)
                     /locus_tag="OPY25_001374"
     CDS             complement(32513..34198)
                     /locus_tag="OPY25_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HCS0927025.1"
                     /translation="MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSVQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGIASTQLSSALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDVRRVKTIADRIGFISIHSQVTDLLAFCAFFII
                     GLMIGMITFQFRNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLM
                     VFMAGVGLSAGSGISNGLGAVGGQMLIAGLVVSLIPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIIWPGLG"
     gene            34469..34846
                     /locus_tag="OPY25_001375"
     CDS             34469..34846
                     /locus_tag="OPY25_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HCS0927026.1"
                     /translation="MKHKHGWASVVCCFVLFIVVCLSLTMHVQGAFRAAGHPEIGLLF
                     FTLLGAVASFCSHRREVIRPLIGAMLAAPFCLVLMRVVFMPTRSFWQELAWLFSAVFW
                     CALGALCYLFISSLFSHRRKKRR"
     gene            complement(34878..35141)
                     /locus_tag="OPY25_001376"
     CDS             complement(34878..35141)
                     /locus_tag="OPY25_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrxA family glutaredoxin"
                     /protein_id="HCS0927027.1"
                     /translation="MFTVIFGRPGCPYCVRAKELAEKLSKERDDFNYRYIDIHAEGIT
                     KADLEKTVGKPVETVPQIFVDQKHIGGCTDFEAWAKENLNLFA"
     gene            35311..35601
                     /locus_tag="OPY25_001377"
     CDS             35311..35601
                     /locus_tag="OPY25_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjC family protein"
                     /protein_id="HCS0927028.1"
                     /translation="MRTIGVLPKSVLILECLGMILLALALLSLNHYLTLPAPFNTSLA
                     GVLMVFLGVVLILPAAVAMMWRIAQLLAPQLMKRPPDISSRSDREKHNESDH"
     gene            35585..36307
                     /gene="nfsA"
                     /locus_tag="OPY25_001378"
     CDS             35585..36307
                     /gene="nfsA"
                     /locus_tag="OPY25_001378"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HCS0927029.1"
                     /translation="MSPTIELLCGHRSIRHFTDEPVTDAQREAIIAAARSTSSSSFLQ
                     CSSIIRITDRALREALVPLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMGQNALTAAESLGLGGVYISGIRNNIESVTELLKLPKHVLPLFGLCLGWP
                     ADNPDLKPRLPAELVVHENQYQPLDEKLLARYDEQLAEYYLTRGSNTRRDTWSDHIRR
                     TLIKENRPFILEYLHKQGWATR"
     gene            36365..37267
                     /gene="rimK"
                     /locus_tag="OPY25_001379"
     CDS             36365..37267
                     /gene="rimK"
                     /locus_tag="OPY25_001379"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HCS0927030.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLR
                     SLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGG
                     VASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGV
                     DIAGRMIQWIERHATPEFCLKIGG"
     gene            37364..37840
                     /locus_tag="OPY25_001380"
     CDS             37364..37840
                     /locus_tag="OPY25_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HCS0927031.1"
                     /translation="MISLVVPTLDTLRQWLDDLGMNFFECDTCQALHLPHMQNFDGVY
                     DAKINLVDNTVLFSAMAEVRPSALLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFEWFVRQSEEQISMVILEAGAHQLLFNAEEDAQKTSAVDHFLH"
     gene            38189..39301
                     /gene="potF"
                     /locus_tag="OPY25_001381"
     CDS             38189..39301
                     /gene="potF"
                     /locus_tag="OPY25_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HCS0927032.1"
                     /translation="MTALKKKWLSGLVAGALMVVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGINVIYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPGWKNLDPELLKLVAKHDPDNKYAMPYMWATTGIGYNVDKVKAVLGDDAPVNSW
                     DLVLKPENLEKLKSCGVSFLDAPEEIFATVLNYLGKDPNSSKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDTCVAIGWAGDVWQAANRAKEAKNGVNISFSIPKEGVMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRLDVIAHISDHVFYANANKEATALVSQQVRDNPG
                     IYPPADVRAKLFTLKVQEPKIDRVRTRAWTKVKSGK"
     gene            39389..40522
                     /gene="potG"
                     /locus_tag="OPY25_001382"
     CDS             39389..40522
                     /gene="potG"
                     /locus_tag="OPY25_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HCS0927033.1"
                     /translation="MNDAPHRPQVKTRKALTPLLEIRNLTKSFDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEPPSSGQIMLDGVDLAHVPPYQRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEITSRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRLKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGLLKAREEDGLVIDAPGLV
                     HPLKVDADASVVDNVPVYVALRPEKIMLCESPPADGYNFAVGEVAHIAYLGDLSIYHV
                     RLKSGQMISAQLQNAHRYRKGLPTWGDEVRLCWEADSCVVLTV"
     gene            40532..41485
                     /gene="potH"
                     /locus_tag="OPY25_001383"
     CDS             40532..41485
                     /gene="potH"
                     /locus_tag="OPY25_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HCS0927034.1"
                     /translation="MSTLEPPARISKPGGAALWLARMQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTDLLEWADGQLSITLNLGNFLQLTDDPLYFEACLQS
                     LQIAGISTICCLLLGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNVLLWLGVIDQPLTILHTNLAVYIGIVYAYLLFMVLPIYTALTRIDYSLVEAS
                     LDLGARPMKTFFSIIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            41482..42327
                     /gene="potI"
                     /locus_tag="OPY25_001384"
     CDS             41482..42327
                     /gene="potI"
                     /locus_tag="OPY25_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HCS0927035.1"
                     /translation="MNNLPVVRSPWRILILVLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELFRDTAMMSAVGLSLTIAACAATMAVVLGTIAAVVMVRFGRFRGANGF
                     AFMITAPLVMPDVITGLSLLLLFVALGHTIGWPSDRGMLTIWLAHVTFCTAYVAVVIA
                     SRLRELDRSIEEAAMDLGAAPLKVFFVITLPMIMPAVISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGVVGIIGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            42401..42874
                     /locus_tag="OPY25_001385"
     CDS             42401..42874
                     /locus_tag="OPY25_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HCS0927036.1"
                     /translation="MGFIKQSTSSHARLNVPTLVQVAAMAIILIRGLDVLMIMNTLGI
                     RGMGEFIHRSVQTWSLTLVFLASLVLVFIEIYCAFSLVKGRSWARWVYLAAQIIVSGY
                     LWAASLGYGYPELFSIAGESKRDILHSLVMQKLPDLLILFLLFIPAPSRRFFRLQ"
     gene            42917..44044
                     /gene="rlmC"
                     /locus_tag="OPY25_001386"
     CDS             42917..44044
                     /gene="rlmC"
                     /locus_tag="OPY25_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HCS0927037.1"
                     /translation="MQCALYDAGRCRSCQWITQSVNEQLSAKTADLHRLLAGLPVEQW
                     CAPISGPEQHFRNKAKMVVSGSVEKPLFGMLHRDGTPVDLCACPLYPASFAPVFSALK
                     PFIARAGLTPYNVARKRGELKYLLLTESQFDGGMMLRFVLRSETKLTQLRAALPWLRA
                     QLPQLRVITANIQPVHMAIMEGETEIYLTDQQALAERFNDVPLWIRPQSFFQTNPTVA
                     SRLYATARDWVGQLPVRHMWDLFCGVGGFGLHCATPQMQLTGIEIAPEAIACAKQSAA
                     ELGLTRLHFQALDSTQFATAQGETPDLVLVNPPRRGIGKPLCDYLAQMAPRFIIYSSC
                     NAQTMAQDIRHLPNYRIQRVQLFDMFPHTAHYEVLTLLCRL"
BASE COUNT         9884 a        11237 c        12403 g        10521 t
ORIGIN      
        1 cctgaaacgt gcattatttt agtgaaaaaa tatcgctgcc cagatggtta tagtccactt
       61 tctgtaattt gaaattggtg atataaacgg gcccggcttt ctgttccgaa ataaatcgat
      121 agcgattttt gatctcttta gcgctaattc ctgtccattg cgagaaaaaa ctcaggaaat
      181 cgttcgcgga acggcgagct ttaatgatcc gatgcgcttt actgtcgctg gatagcacca
      241 taaacggcac ctggaagttt tgctggaatt tgtcgtcatg cgccaggtac tgtaccgctt
      301 tgccgcgctc tttaaacgcc agcctgtgat cggagaaata gacgagcgaa aaactgtcgc
      361 cgctatgacg aagctgagta tagagctgac ggagcaaatc gtcggtttgc gtcatggtgt
      421 ataaataaca agacgtctct ttcgactgga caaacgtcgc gtattttcca tgagtacggt
      481 cgcaggcctg gggatgcgat cccattaaat gcaacacaat caactgcggt tgcgtgcgtt
      541 ctgtcgccaa tacctgcgcc gtcatggtta acagcgcgtc gtcgcgagta tttttatccg
      601 cttcaaaatc gccgtttttc aggaaatgcg cttcatcggc gcgtttggcg atactggcga
      661 tggccgtgtc gtattcgccg atttgcccct gattggaaaa ccaccatgtc tgaaaaccgg
      721 cgcggttagc cagcgtgacg aagttatcct gatactgcgg tttgttatcc accacgcgat
      781 tgagcgttaa accgagcgat ttttgcgttg agccgctggc ggcgatgtaa tccataaaga
      841 agtcgccatt cacatggctg gcgaaggggg tattatccca gtggccgccg aaagcgccca
      901 tggcatcccg tcgcgcgctt tcaccaatca ccacgacata gatgtgatat ctgggtttca
      961 ccgcagtaac cgtccagcta tcttttatgc cggatagctg cgccatacgg tgctgctctt
     1021 caatgacttc gttgttattg acgataacgt ctttggcgaa gcgaaaaacc ggatagccgg
     1081 tatcaataac cttaaaaacg ccgccccagg ccagattttg taccggcgcg acgaaaaatg
     1141 ccgcgacgct aatcagcagg cacaggctgt cgaggctatt ccagcgcggc ctgacctctt
     1201 cttttcggcg gcgaagcgca ataataccca gcgcaaaaat aaaaagtccg gtcaggtagc
     1261 tataccacgg gaagatggtc aggatttcgc tcgactcttc catattggtg gagtgcagcg
     1321 ccagcagcgt attaaagttc ggcgcgccgt aagcctggcc aaagggaaaa tagcaagcgg
     1381 ctaccagcga acagatgccg agcagcgctt tttgtccgcg aggcaggtag cgccagagca
     1441 gcagcaacag gcaggtaaac gccgcggtat aaagcaggct aaaggggtag ccgagcgcga
     1501 ggttaatcag cagcgactgt aaaaagtaga ggcccgccca tgggcttaca gcccgacgac
     1561 gggccagaag tgaatcgata agggttgaat tcatatgcca ctattgcaaa aacgccatgt
     1621 gctaaccctg gcgcgaaggg tcattacctg cctgattatg cgtaaaaaag gtattgggtt
     1681 cgcaacggcg agtcgcaaaa tattcaaggc tgccagaaga tagagcgtgc gggtaagaag
     1741 gccaaccgcc ggaaagaaaa tgttttgcga agagaatagc aaaaccacaa aaaaaacagg
     1801 ggaaatgggc gccatttccg ttgaggatgc aaaataaagc ggcgtaccgc accgccgcgt
     1861 tatttcgtgg aagggttatc ctgttccggt ttgccgttga tcatatcgca caacatagag
     1921 agcagcatta accggacttt aaagggagag tgactgaaca cgcgtataca cctcttaaat
     1981 tcgttcatat aaacctcctg atgtttctat cccatcgatc cgtgagggat gtctgcatta
     2041 catacagata tagcacaggc tatgttttat agctattgct aaaacgttaa ttttttgtgc
     2101 ccggacaact ctggtttaca atgagcgctc tgtcagctga cgcgttaacg cgtcacagaa
     2161 acgaggaagc aaaatgggtc gtcgcgcagg tacgccaaca acaaaaaaag tgacgcaatt
     2221 ggtgaacgta gaagaacacg ttgaaggatt tcgtcaggtc agagaggcgc atcggcgtga
     2281 gttgatagac gactacgttg agctgatttc cgatttaatt attgaggtag gggaagcgcg
     2341 tcaggtggat atggcggcgc ggctcggcgt ctcccagccg actgtggcca aaatgcttaa
     2401 gcgcctggca tcgttaggat ttattcaaat gatcccctgg cgcggcgttt ttctgacgcc
     2461 ggaaggggag aagctggcgc aggaaagccg cgagcggcat caaattgtcg aaaatttttt
     2521 actggtatta ggcgtaagcc cggaaatcgc gcgtcgtgat gcggaaggga tggaacacca
     2581 tgtcagccaa gagacattag atgccttttt ggccttcacg caacagcatg gaacatctgc
     2641 agaatgaatc tggccttttt acgggcgctg cggcgtgacc gtttttttca gttgttgatc
     2701 attgtgggga tggcgttaag cctgtttgtt ccttttgcgc cccgcgcctg gcctggcgcg
     2761 attgactggc acaccattat taccctcagt gggttaatgt tgctcactaa aggcgttgag
     2821 ctgagcggct attttgatgt gctgggacgc aagatgacgc gccgatttca taccgagcgg
     2881 caactggcga tgttcctggt gctggctgcg gcggcgctgt cgacctttct gacaaacgat
     2941 gtcgcgctgt ttatcgttgt gccgctgacg ataacgttaa aaaaactgtg cgcgattccg
     3001 gtcaaccgat tgattatttt tgaagcgtta gcggtgaacg ccggttcgct gctgacgcct
     3061 gtcggtaatc cgcaaaatat tctgttgtgg ggacgctccg gcttaagctt tgctgaattt
     3121 agcgggcaaa tggcgccgct tgccgtcatg atgatgctga cgttactgct cctgtgctgg
     3181 ttttgttttc cgggtagggc gttacagtat cataccggta cgcgttcgcc gcagtggcag
     3241 ccccgtctgg tgtggagttg cctggcatta tatgtcgttt ttcttaccgc gctggagctc
     3301 aggcaagagt tatggggact ggtgttggtg gcggctgggt ttattgtgct ggcgcgcagg
     3361 gtgatagtca gcgtggactg gacgctgctg ctggtattta tggcgatgtt tattgatgtc
     3421 catctgctaa cgcaattgcc ggcgttgcag ggcgttttca accaagttgg cgcactgtct
     3481 cacctgggac tttggctaac cgctatcggc ctgtcgcagg ttatcagtaa tgtgcccagt
     3541 accattctcc tgctgaacta tgtaccggcc tcgacgttgc tggcgtgggc ggtgaatatc
     3601 ggcgggtttg gtctgctgcc ggggtcgctg gcaaatctta ttgctttacg gatggcgaac
     3661 gatcgccgaa tctggtggcg atttcatttc tattcgctgc cgatgctggc atgggcggcg
     3721 ctggtgggat atggattatt gcaactgatg ccgtaagaga agcccgatag tgtctatcgg
     3781 gcttcgcagg cagagtctgt cagttcagac gaaccggcat cccggaacga tcctgaactg
     3841 cctgttgtac gacggtctga tcaacgtcag gctcgttggt gacggccagg atactcttat
     3901 taagcgtgat cggcaccgct tccttacctt caaactgcgc ttccgtcgtt gacagcgggt
     3961 tatgcacctc aatgtaacgg ctaccgtccg gctcggtggt ggcttttacc ggttcatcga
     4021 taaactgcac gcgggtaccg accggcacat tttcaaacag gaatttgata tcgtcgttgc
     4081 gcagacgtac gcagccgtgg ctcacgcgaa gcccgatgcc gaagttggcg ttggtgccgt
     4141 gaatagcata caggcgaccg atgtacagcg cgtacaggcc catcgggtta tccgggcccg
     4201 caggcacgac ggcaggcagc ggctcgccgg cggcgcgata ttcagcgtgc atttttgccg
     4261 taggcgtcca ggtcggaccg gcttttttac gttcaacttt ggtcgtccag ttgataggcg
     4321 tgtctttacc taactgaccg atcccaatcg gcaggacgat aacggtgttt gtgcctttcg
     4381 ggtagtaata gaggcgcatt tccgcgctat tgatgataat gccttcgtgt acggtatccg
     4441 gcaggatcag ctgctgcgga atattcagca cggtaccgcc cttcggcagg aaggtatcca
     4501 cgccagggtt ggcttccagc atgttggaga gccccatctg atactccgcg gcaaaatact
     4561 ccagcggctg ggtattgccc tccggaacgg tgatgacctg attttgccca attaaacggc
     4621 taccatcggt aggcagcggg taagtgactg ctgaggctgt tttacaaaaa ccaactacag
     4681 cgaaagccgc cgcgaaaagc gttgttaatt tcatattcat gttatgcgag attctgtgcc
     4741 aagcaggcta gtaggttgag aattctgtca tgttgggagc gcattatagg tgcattccag
     4801 taaacaggga attcagatgt gtacgaaatc acgttttttt ccccttacgg ttcagtgtag
     4861 ccctttgtat agggcgcgat cttatttcag acttgtggca taataagcgg tttgtcacat
     4921 cttttttcag gataagcctg tgttagtttc cagcaacgtt accatgcagt tcggcagtaa
     4981 gccgctgttc gaaaatattt ccgtcaaatt tggcggcggc aaccgttacg gcctgatcgg
     5041 cgccaacggt agcggaaagt ccacttttat gaaaatcctc ggcggcgacc tggagccgac
     5101 gctgggcaat gtttccctcg atccgaatga gcgcatcggt aagctgcgtc aggaccagtt
     5161 cgcttttgaa acattcaccg tacttgatac tgtcattatg gggcatggcg aactgtggga
     5221 agtcaagcag gagcgcgacc gtatctatgc cttgccggaa atgagcgaag aagacggcta
     5281 taaagtcgcc gatctggaag taaaatacgg cgagatggac ggttattccg ctgaggcgcg
     5341 tgcgggcgaa ctgctgttgg gggtgggcat cccgctggag cagcattacg gtctgatgag
     5401 tgaagtcgcg ccaggctgga aattgcgtgt gctactggcg caggcgttat tctctaatcc
     5461 ggacatcctg ttgctcgacg aaccgaccaa caacctggat attgatacta tccgttggct
     5521 ggagcaggtg ctgaacgagc gcgatagcac gatgatcatc atttcgcacg accgtcactt
     5581 cctgaacatg gtttgtacgc atatggcgga tctggattac ggtgacttgc gcgtctatcc
     5641 gggtaactat gatgagtata tgacggcggc gacccaggcg cgtgaacgtc tgttggccga
     5701 taatgcgaag aaaaaagcgc aaattgccga gctgcaatct tttgttagcc gttttagcgc
     5761 caatgcctct aaatcgcgtc aggcaacgtc gcgcgcgcgg cagattgata aaatcaagct
     5821 ggaagaggtg aaagcctcca gccgtcagaa cccgttcatc cgttttgagc aggataaaaa
     5881 actgttccgt aacgctctgg aagtggaggc gctgacgaaa ggttttgata acggtccgct
     5941 gtttaaaaat gtcaatttgc tgctcgaagt cggcgagaag ctggcggtac tcggcaccaa
     6001 tggcgtgggt aaatctacgc tgctgaagac gctggttggc gatctggacg ccgatcacgg
     6061 caccgttaaa tggtcggaaa acgcgcgtat tggttactac gcgcaggacc acgaatatga
     6121 attcgaaaat gacctgacgg tgtttgaatg gatgagtcag tggaaacagg aaggcgacga
     6181 cgagcaggca gtgcgcagta ttctgggccg cctgttattt agccaggatg atatcaaaaa
     6241 gcctgcgaaa gtcctctccg gtggcgagaa gggccgtatg ctgttcggca aactgatgat
     6301 gcaaaagccg aatatcctga tcatggacga accgactaac cacctggata tggagtcgat
     6361 cgaatcgctg aatatggcgc tggagctgta tcagggcacg ctgatctttg tttcgcacga
     6421 ccgtgagttc gtcagctcgc tggcaacccg cgtcattgaa attacgccgg agcgcgtggt
     6481 ggacttcagc ggtaactacg acgattattt gcgtagtaaa gggattgaaa gctaaacact
     6541 gacgcccggt ggcgctgtgc ttaccgggcc tacgtatcct ggcgcgtaga tctggtaaga
     6601 cgggtgcgcc cagacaaagg gcacaccgca gttgagcggg cagggctgta cgaccgtcaa
     6661 acgtccatac ctaatgcccg cttgccgtga atattcagat cgcgcagcgt gaaacgccct
     6721 tcccaggtgg tttcatagtc ctcgcgcggg aaatcgtccg gtgatgcgcc tgtctccagc
     6781 gccgctttca ccttacgcgc ataggccaga tttttctcac acattggcgc ggcaggaatg
     6841 tacatcacat tgccccagcc ctgctgattt tcgacggggg cgacggagtg gatgacatcg
     6901 caatgccacc acacggaatc cccggcttcc agcggcggaa tgctggttaa cgccgccatc
     6961 agtaaaggat gccactgttc agaaatcggc agcacccggc ccggcgcgac gccgcataat
     7021 tcatcttccg ggacatcatc cagcagcggg cgcagcagaa tatacgccat cgcctccgga
     7081 atagggacga catgaagcaa cccctgaccg ggcagcatat cggagagcgc ggtccagccc
     7141 tggaaggtgc gaaataccga gcattttgtg gtgttatcca ccgtgtactc ttcaacttcg
     7201 gtacggtgcg ccgcattcca cggatcgtac tgctcgacgt tgccgttaaa cacgctggcg
     7261 aatacctgct gataggctgg tagcagccag cgctccagcg cgccggagtc ggtatgcgct
     7321 cccagtcctt tggatgtggt gcccggcggg cggcgacgga tgcgatccgg gtaaatgatg
     7381 ctgatatccg gattaaacca tcgcttgccg tcgcgctcta cctgccacag acggttgagg
     7441 aacgactgcg ccagcgccat ctcttcactt tggcgggcct gcatttgcgc ctgcgaccag
     7501 tagacaggat agatttcagg ccgggaggcg ctcagcgtac cgaaaaaatt atcccccggt
     7561 cctttataca cctcgtcaaa atggttcttg tccagatagt cgagcatcga ctggtcccat
     7621 gccagcgcct gttcgcgtgg aaaatgacct ttaatcaccg cgcacccgcg gcgcttaacc
     7681 tcggcgcggg tagcatcgct aatgttgccc gtcgccagtt cgctaaaagg gataattggc
     7741 cataccggct gtccctgcgc cttcagatcg ttaatttccg ccacccgggc tgctatggtg
     7801 gcgctcaaac ggtcgaacac cgcctgtacg tcgccgattt gcgcgcgtag cgcctgcttc
     7861 atctgacgaa tggccgcttt tgggtcggcg ggcagcgttt cgtaggtaaa aggagtcgtc
     7921 atatcaacct caccatcttt cgttcgaaag taaaattagt tacatgtgat actttaagtt
     7981 aaaataaggt taatgcaagt ttaaaatatt gcaggggcgc acaaggaggg aagcgagagg
     8041 aaaacgtaag gtggccagga cgccttaatg tcttatgcgg ctattccttt cgttcagcca
     8101 cttttcattc gaaataaatt tgtggttctg ctcacattgt tattaaaatg tttctggtcg
     8161 cagttacagc caggagctta agtatgaccg ttaacgttgt cgttaccgat atggacggca
     8221 cttttctcga cgatgccaag cagtacgatc gtgtacgctt catggcgcaa taccaggaac
     8281 tgaaaaaacg taatatcgaa tttgtggtcg ccagcggtaa tcagtactat cagttgatct
     8341 ccttcttccc cgagctgaaa gacgaaattt ccttcgtcgc agaaaatggc gcgctggtgt
     8401 atgaacatgg caagcagttg tttcacggag agctaacccg gcatgaatcg cgtattgtga
     8461 ttggcgaact gctgaaggat aagcagctta acttcgtcgc ctgcggtctg aaaagcgctt
     8521 atgtcagcaa aaacgctccc gagactttcg tggcgctgat ggccaaacat tatcaccgcc
     8581 tgcagccggt aaacgattat cacgacattg acgatatcct gtttaagttc tccctgaatt
     8641 tgcccgatga acaaattccg ctggttatcg acaaactgca cgtatctctg gatggcatca
     8701 tgaagcctgt caccagcggc ttcggtttta tcgacctgat tatcccggga ctgcataaag
     8761 cgaatggcat cagtcgtctg ttaaagcgct ggaacaggtc gccacagaat gtcgtcgcca
     8821 ttggcgacag cggtaatgat gcggaaatgt tgaaaatggc gcattactct tttgccatgg
     8881 gcaatgccgc agacaatatc aaagcgcttt cacgttatca cactgatgat aataaccatc
     8941 aaggcgcgct caacgtcatt caggccgtgc ttgacggcac cgatcccttc tgattaacag
     9001 gcctgcgtag gcctgttaag cgtagcgcca tcaggcagtt cggacatatt gccgatggcg
     9061 cctgggcaaa ttacagcata tgttcggtac gggcgatgat atcgtcctgc gcgtccggcg
     9121 acagcgcggt gaagaaggcg gagtagcctg ccacacgcac gaccagatcg cggtactggt
     9181 ccggatgttt tttcgcatcc agcagcgttt cgcgtgacac gatgttgtac tgaatatgcc
     9241 agcctttatg cacctcaaag aacgtccgta gcagaaccat cagtttctgt ttgtcggatt
     9301 cgttttccag cgtcgttggg ttcagtttct gattgagcag cacgccgccg agaatggaac
     9361 cggtaggtaa tttgcctacg gaaccaatca ccgccgtcgg gccgagatga tccgtacccg
     9421 atgcagggct tgcgccttcc gccagcggtg tatgcgcttt gcgaccatcc ggggtagcca
     9481 tagttgcggc gccaaatggc acgtttgctg agatagagga cgtaccggcg taatagttgc
     9541 cgcccacagg gccacgacca tagcgcgggt tatggtattg cttcagctca tcaatatagg
     9601 tctgataagc gcgcgccagc agggtatcga cactgtcatc gtcgttaccg tatttcggcg
     9661 cgccgttaat cagacgctgg cgcagctgct catggggcag cccgtcaaag tcatcggcca
     9721 gcgcggcggc aagctgctgt tgaccgataa cgccctgttc gaagaccagt tttttcacgg
     9781 cggcgaggct gttgcccagg ttggcgatac cgacctgcag accggatacc cagtcatatt
     9841 ttgcgccgcc ttgcttgata ctcttcgcgc gttcaataca gtcgtctacc agcgctgagc
     9901 acagaatatc gtggacgttc tcttccagca tggtgtcgac cacatactca atttcgatcg
     9961 atttgcgcgt gtagtagcga atttgggtat cccaggcggc catcacttcg tcaaaattgt
    10021 taaagttgcc tgcggagagc gccttttcct gcggcagaaa taccttgccg ctggtggcgt
    10081 cgcgaccgcc ttccagcgcc gccagcatga cgcgggcgaa gttaataaag ctcatgccgg
    10141 tgcagcgata accccatttc ccgccgacgg cggtttcgat acagccgatc gccgcgtaat
    10201 cgtaagcgtc ctgtggttcg atccccaact tgataaattc cgggatgacg atttcatcat
    10261 tgttaaacgc cggcatccca aagccgcagc ggatgacctg gacgcaggcg tcaaggaaat
    10321 cgttactcat tccggcgtga taacgcacac tgaggttggg ctgggtagaa cgcaaacgtc
    10381 cgcaggactc cagaatagcg taagacagcg gattcactgc gtccattggc tgaccgttga
    10441 taagattctg accgccaatg gtgacgtttt gatacagcgg gctgcccgcg gaagctttag
    10501 agtgcgaacc ggagcggatc ttgtttactt ccagcagttt cagccagcag ctgtgcagca
    10561 gttcaatggc gtgctcacga tccagcgtct ggtttagttc gacatcgcga cgataatagg
    10621 ggtaaagata ctggtccata cgaccaaatg acaccgagtg accgttagac tcaatttgta
    10681 gaatcagttg gatgaagtag cacaattgca gtgcttgcca gaaggtctgc ggcggttggt
    10741 gggcgatcac ctcgcagttt tccgcgatgg taagtagctc tttacgacgg ctttcacggg
    10801 actcttcgcc cgccatctgg cgcgccagcg cggcaaagcg cgtgatatgc tggcttaccg
    10861 cgtccagcac aatatcaatc gccttcagga actgctcgcc atgcagatct tccagcacgg
    10921 tcaggttgat gcgtgagcgg cgctcggcga ctttatcgcg caggtcatca agcccttttt
    10981 ccagcagcag cgggaagttc accgccaggt gcgcgtcacc ggaagtcata ttaccttcgg
    11041 ctttgataat gccagtcgcc agaagccctt tttgttcatc ggtaaacatg ccgtagcagc
    11101 gatcctggac ggtttgaccg cgccaccacg gacagacgtc gtgcagaata cgtttgtttt
    11161 cttcacttac ggaaaaacct gcgccgggcc ggtctgccag gtcgtcgatc tctttttcaa
    11221 tccacgagac ggtatattcc gggaaaatcg gcgcggcgcg gacttcactt gcctggttgc
    11281 cgacgatcag ttcatcgtgt tttatccaga tagtgcgttc cgccaggtga tgggccagcg
    11341 ccagcgcgcg gcgtaccgga atcggtttat ccagatgttg ctgatacatt tcggtataat
    11401 gctgcgcgcg ctcggtacag accggcggtt tcacgatatg taccagcgcg gttttgtgcg
    11461 ccttaatgcg gtcactgagc gtgtccagtt tcagttgggt catgataatt atcctcgtag
    11521 ggtcgcggtt aaaccttttt ggcaggcgta cttctgggca aaatcaagta acgccggtgc
    11581 atccagtggt ttatccgggg catgataggg ctgactgagt aagtggtatt tattgatgcc
    11641 cagcgtgtgg tagggcagaa aatgaatttc cccgacgtgc agttcgtcgg cggcaaagtc
    11701 ggtaatggct ttaatggtct cctcatcggc attaaatccc tgaatcagcg ggacgcgaat
    11761 caccattttt ttgcccgcgg cggcgagttt cctgagattt tccagcaccc gcgaggcgct
    11821 gccatcggtc cactgcttaa acggcccgtc ggcgacgtgt ttcaaatcag ccagaaacag
    11881 atcgatataa ggcagtgagg gcgcaatgta tttccatggg acatgcagac aggtctcaac
    11941 cgctgtatga ataccggcgt catggctggc tttaaacagc tctgccgcca gctccggctg
    12001 cataaacggt tcgccgccgg aaagcgtaag accgccgccg ctgcgatcgt aaaaaggttt
    12061 atcgcgcagt accgtcgcca tgatctcatc cacgcttttt atttcgccgc acacggttaa
    12121 cgcctgtgtg gggcagcaat gcgccaggat ggaaaaatgg gcgtcggtca gtttctcgcg
    12181 atggatgagc aggccgttta gcgcgcgctc aatgacgtcc ggcgcggctt gcgcgcacag
    12241 gtcgcatcct tcgagacaca gccgcgcgtc gtataacaga tcctgagcgc gggcgcggct
    12301 ttccgggttc tggcaccagc gacagcccaa cgaacagcct ttgagaaata ctacggtacg
    12361 gataccgggg ccatcgtggg tggaatagcg ctgaatattg aagatcataa acggcctctc
    12421 ttatttcatg taaagattaa attactttcg aatgaaagtt atcttgatgt gcgtcaacga
    12481 atggagaggt tctgacaaag aggcgttaaa tgaggtacaa catcacgggt tgaggctgtg
    12541 atatggcgtt taagatgatg ccgcgctgct tgagccgatc gtcagtcgga gcttgggtaa
    12601 gctggctttg cgtctgatgg cagtaattat ctgttgatac agcacggcca tagaccgtgc
    12661 tttggtatgt ttatccgtaa agtgactact gcccgcagac ctcacagccg gggttgcgca
    12721 tcaacttcat ttcgcggaac tgacaggtca tcgcatcgta catgacgatt tttccgctgg
    12781 caggctgacc gtaatgcgcc agtagcttaa tggcctccat tgcctgtagc gaaccgatca
    12841 cgccaatcag cggcgccatc accccagctt ctacgcaggt cagagcgttt tcgccaaaca
    12901 gacggctcag gcagcggtaa cagggttcgt tttcccgata cgtaaagacg gtaacttgtc
    12961 cttccatacg aatggccgcg ccggagatta gcggcacttt cgcgatatag cacccggcgt
    13021 taagttgatt acgtacgcta acgttatcgg tacagtccag caccagcgaa tgcccggcaa
    13081 tcaggctggt catagcgtcg tcgtccagcc gcgcgttaac gggcgtaatg gtaatatgcg
    13141 ggttgattcg cgccagcgcg tcgcgggcgg actctacctt tggctgcccg accgtggcgt
    13201 cgctgtgcaa ggtttgacgc tggagattgg aaacggaaac ggtatcaaaa tcgagtagcg
    13261 tcagttgccc gacgccagcg ccggccagat actgcgttgc cgcgcagccg agtccgccca
    13321 gcccgaccac taatacccgc gcatctttta acgcttcctg cccttcaaaa tcgaagccgc
    13381 gcagaataat ttgtcggtta tagcgcagca tctcctggtc gctaagttcc gccattacag
    13441 gcctccgaac agagcattaa acggctcgac ttccacccat tctcccggct caacattgcc
    13501 gcgttcacgc tccagcacaa taaagcagtt gcccagatta aacgagctga aaatatgtga
    13561 gccctggtgt ccggtggtcg tgacctccag ttcgccgttg gcgctacgtt gcaggatgcc
    13621 gcgctggaaa tcgagacgcc ccggcgtttt cttcaggcga gatgttgtgc gtacacgctg
    13681 gcgcggcggt acagcgcttg ccgtattgcc gccaagcttc gccagtaagg gctgaaccag
    13741 ttgataaaac gtgagcgccg cagagactgg attccccggc aggccacaga accagctatt
    13801 actgagcttg ccgaaggcaa acggtttgcc tggcttgata gccagcttcc agaaggcgat
    13861 ttcgcccagc tcctcaagga tggttttggt atagtccgct tcaccaaccg agacgccgcc
    13921 ggagcttatc actacatcgg cctggctgtc ggcgtcgaca aacgcggcgc gaagcttacc
    13981 gggatcgtca ggaataatgc ctaaattgat cacttcgcag ccaagctgtt gcagcatcaa
    14041 atgtatagtt agacggttag tgtcataaat ttgtcccgcc tccagcagct ggcccggaag
    14101 ctggagctcg tcgccggtcg agaacagcgc tacgcgcact ttacgtacta cctgcgcatc
    14161 ggcaattccc agcgacgcca gcaccggcag ttcggcagta gtcaggcgcg taccggctgg
    14221 aaagaccacc gcatcctggc gaatatcctc gccgcggcgg cggatgtttt gtccgcaacg
    14281 aacatcggtg gtaaaacgca cgccgtcatc agtttgttcc gtctgctctt gcatgacgac
    14341 cgcctcgcaa cctgccggca ccggggcgcc ggtcataatg cgaatacagg ttcccgcagg
    14401 ccattctcct tggtaaggct gaccggcaaa tgctttgccg gcgacgggca gcggcttatc
    14461 ggcggacaaa tccgccacac gtaccgcata accatccata gctgaattat caaagccggg
    14521 gacatcaagg ggagatacga tatcggtcgc caggatgcgg ccaaagcagt tcatcagcgg
    14581 caacgtttct acggcggtga gcggggtaat acgtgaaagc atctgggtca gcgccgtttc
    14641 aagcggcatc aatccggcgg aaaattccat gaacatactc ctgcgaggca aaatcgaatc
    14701 cggctattat gtcagaaaac agtggcgggc agtatgctac ctcagtctta gagacggcct
    14761 tgcgccttta cataccttac gcatctttct atattcaaaa atcgaatgaa taactcacaa
    14821 caattctgat agttatagta aaagttgtgt gccaccgtta atggacccta aaaatgaata
    14881 aagcagtgat tgcgattcac ggcggcgcag gcgcgattgc tcgcgcgcaa atgagccatg
    14941 agcaggagct acgctatatc caggcgctgt cagagattgt cgaaagcggg caaaagatgc
    15001 tggaagcggg tgacagcgcg cttgatgtag tgacggaagc ggtgcgcctg ctggaagcgt
    15061 gtccgctctt caatgcgggt atcggcgcgg tctatacccg agacggaact catgaactgg
    15121 atgcctgcgt gatggacggc aataccctga aagccggagc cgtcgcgggc gtgagtcatg
    15181 ttcgccatcc tgtgctcgcc gccagactgg tgatggagcg cagcccgcat gtactcatgg
    15241 tgggggaagg ggcggaaaac tttgcctttt cacaggggat ggcgcgcgtt tcgccggata
    15301 tcttttccac cccggcgcgt tacgagcaat tgctggcggc gcgtgcggcg ggcgaaatgg
    15361 cgctcgatca cagcggcgcg ccgctggacg aaacgaaaaa aatgggtaca gtcggcgcgg
    15421 tggcgcggga taaattcggc aatctggcgg cggcaacgtc taccggcggg atgaccaata
    15481 aattgcccgg gcgcgtcggc gacagcccgc tggtcggcgc cgggtgttat gccaacaacg
    15541 ccagcgtcgc cgtttcctgt accggaacgg gagaggtctt tattcgcacg ctcgcggctt
    15601 acgatatcgc cgcattgatg gaatatggcg gactcagcct tgccgacgcc tgtgagcgcg
    15661 tggtgatgga aaaattaccg gcgctgggcg gcagcggtgg attaatcgcc gttgatcacg
    15721 aaggtaatgt cgcgttgccg tttaacagcg aagggatgta tcgcgcctgg ggatatgccg
    15781 gggatacgcc taccacagga atttaccggg aataaggagc cgcaggtgcc gcacagcgat
    15841 gaactggata gccgcgatgt tctgtccgtc agtggcctga atatcgcgtt tcaccacgaa
    15901 gggcaacagg tagacgccgt gcgtaatgtg tcattacgcc tgaagcgtgg agagactctg
    15961 acgattgtcg gcgagtcggg ctcgggaaaa tcggtgacgg cgctggcgtt aatgcggctg
    16021 attgagcagt cgggcgcgaa cgtgcgctgc ggcgaaatgc tgttgcgtcg gcgtaatcgc
    16081 caggtgattg agctgtctga gcagagtgac gcgcagatgc ggcgtgtgcg cggcgcggat
    16141 atcgccatga ttttccagga gccaatgacc tcgctcaacc cggtatttac cgttggcgag
    16201 caaattgccg aatctattcg tttgcatcag ggggccagcc acgaagaggc gctggcggaa
    16261 gcgaaacgta tgctcgatca ggtacggatc ccggagtcgc aggcgatttt atcgcgttat
    16321 ccgcatcagc tttccggcgg gatgcgccag cgagtcatga ttgcgatggc gctatcctgc
    16381 cgtccggcgg tattgattgc cgatgaaccc accacggcgc tggatgtcac tatccaggcg
    16441 caaattctgc aacttatcaa agtgttgcag caagagatgt cgatgggcgt gatttttatc
    16501 actcacgaca tgggcgtcgt ggcggatatt gccgatcgcg tgctggtgat gtatcagggc
    16561 gaggccgtgg aaaccggcag cgtagagcag attttccatg cgccgacgca tccttatacc
    16621 caaacgttac tggccgccgt ccctcagctt ggcgcgatgc gaggccactc gctgccacgc
    16681 cgtttcccgt tgatttccgc tgacgaaccg gccctttatg aatcgcagat tgagcaagac
    16741 acggtggtgg aaggcgaacc tattctccag gttcgggggc tggtgacgcg attcccgctg
    16801 cgtagcggtc tctttaaccg cgttacgcgt gaagttcatg ccgttgagaa tatcagtttc
    16861 gatctctggc ccggcgaaac gctatcgctg gtgggcgagt ccggtagcgg aaaatcgacg
    16921 accggacgcg cgctgctgcg gttggttgaa tcccggcagg gggagattat ctttaacggc
    16981 cagcgcattg acacgctgtc tgcgggtaaa ctccagccgt tgcgccgcga tattcagtgt
    17041 attttccagg acccttacgc ctcgctcgac ccgcgccaga ccgtggggta ttccattatg
    17101 gaacctttac ggattcatgg tctggggcag ggggacgctg cggcaaagcg cgtggcctgg
    17161 ttgcttgagc gtgtcggatt acgtcctgaa catgcctggc gttatccgca cgagttttcc
    17221 ggcggtcaac gtcagcgcat ctgcattgct cgcgcgctgg cattgaatcc taaagtgatt
    17281 attgctgatg aggcggtctc cgcgctggat gtttccgttc gcggacagat cattaattta
    17341 ctgctcgatt tacaacggga aatggggatc gcctacctgt ttatttcgca tgatatggcg
    17401 gtcgtggagc gaattagcca tcgcgtggcg gtgatgtatc ttggtcaaat tgttgagatg
    17461 gggccgcggc gcgccgtttt tgaaaatccg cagcatcctt atacgcgtaa attgatggcg
    17521 gcggtgccgg ttgccgatcc ctccagacac cggccgcggc gcgttctgct atcagatgat
    17581 atacccagca atattcataa acgtggcgaa gagacgcccg ccgtttcatt acagttggtc
    17641 gggccgggac attatgttgc gcggccgctg caggataatg cgctctcgcg cttataacat
    17701 tcagacaggc agggtttcag gagaacaaca tgacgcaatt tattacgcat aaatggctgg
    17761 cggcgctggg actggcctca tccattgcgg cttttccggc cctggcggcc aaagatgtgg
    17821 tggtggcggt agggtctaat ttcaccacgc tcgatccgta tgacgccaac gatacgctct
    17881 cgcaggcggt ggcgaagtca ttttatcaag gtctgtttgg cctggataaa gacatgaagg
    17941 taaaaaacgt cctggcggaa ggctataccg tttctgatga cggtctgacc tacaccatta
    18001 ccctacggca gggggtgaaa tttcaggacg gcgcggattt taatgcggcg gcggtaaaag
    18061 cgaatctcga tcgcgccagc aatccggata accacctcaa gcgttataac ctgtataaaa
    18121 atatcgcaaa aacggaggtc gtcgatccgg caacggtaaa aattaccctg aaacagccgt
    18181 tctccgcttt cattaatatt ctggcgcacc cggcgacggc gatgatctcg ccgcaagcgc
    18241 tggaaaaata tggcaaggat attggttttc atccggtcgg cactggtcca tatcagcttg
    18301 aaacctggaa tcagaccgac tttgtcaaag tgaaaaagtt cgccggttac tggcagcagg
    18361 gcttacccaa gctggattct attacctggc gtccggttac tgacaacaat acccgcgcgg
    18421 cgatgctgca aaccggcgaa gcgcaatttg cttttcctat cccttatgag caggccgcgt
    18481 tactggcgaa aaataaaaac ctcgaactgg tcgccagccc gtccattatg cagcgttata
    18541 tcagtatgaa tgtgacgcag aagccgtttg ataatcctaa ggtgcgtgag gcgttgaatt
    18601 acgctatcaa tcgtcaggcg ctggttaaag tggcgtttgc cggatacgcc acgccggcga
    18661 cgggcgtggt gccgccgtcg atagcctatg cgcaaagcta tcagccgtgg ccctatgatc
    18721 cggctaaagc gcgcgaacta ttgaaagagg cggggtatcc agacggtttc agtaccacgc
    18781 tgtggtcatc gcacaaccat agcaccgcgc aaaaagtgtt gcagtttacc caacagcaac
    18841 tggcgcagat tggcattaaa gcccggataa ccgcgatgga cgccggccag cgcgccgcgg
    18901 aagttgaggg caaagggcaa aaagagagcg gcgtgcgaat gttctatacc ggctggtcgg
    18961 cgtcgacggg cgaagctgac tgggcgttat cgccgctctt cgcatcacaa aactggccgc
    19021 cgacgcagtt taataccgct ttttacagca acaagcaggt cgacagcgat ttggcggcgg
    19081 ccttaaagac taacgatccg caggagaaaa cacgattata caaagaggcg caggatatta
    19141 tctggaaaga gtcgccctgg ataccgttgg tggtggagaa attggtttct gcgcacagta
    19201 aaaatttgac cggtttctgg attatgccgg ataccggttt cagctttgac gatgcggatt
    19261 tgaagtaagt aatgcgatgg ggctggatgg cgcgcgcgtt gtccgccatc cggtaaaagg
    19321 ttcgtgtgat gcttaactat gttctcaagc gcctgctggg attaattcct acgctgttga
    19381 ttgtggcagt gctggtgttt ttatttgttc atttgttgcc cggcgacccg gcgcggctga
    19441 tagccggacc ggaagccgac gcgcaggtga tagcgctggt tcgtcagcag ctggggcttg
    19501 atcagccgct tcatgtccag ttttggcatt acatcaccca tgttttacaa ggcgatttcg
    19561 ggacgtcaat ggtttcccgc cgcccggttt ctgaggagat cgccagccgc tttttgccga
    19621 cgctgtggct gacgataacc agtatgatat gggcggtgtt gtttggcatg gcgatcggca
    19681 tcgccgccgc cgtgtggcgt aatcgctggc ctgaccgggt aggaatgacg cttgccgtga
    19741 ccggcatttc tttcccggct tttgcgctgg gaatgttgtt aatgcagatt ttttccgtgg
    19801 atctgggctg gctaccgacc gtgggggcgg atagctggca acattatatt ttaccctccc
    19861 tgacgcttgg cgcggcggtg gcatcagtca tggcgcgttt tacgcgctcc tcgtttgtcg
    19921 atgtgctgag cgaggattac atgaggaccg cgcgggcgaa aggcgtcagt gaaacgtggg
    19981 tggtgttaaa acatggcctg cgcaatgcaa tgatcccggt cgtcaccatg atgggactgc
    20041 aatttggctt tctgcttggc ggatcgatcg tcgtcgaaaa agtgtttaac tggccggggc
    20101 ttgggcgatt actggtcgac tccgtcgaca tgcgcgacta ccccgtgatt caggcagaag
    20161 tgctgctgtt ttctctggaa tttattctta tcaacttagt ggtggatgtc ctctatgccg
    20221 ccattaatcc ggctatcagg tataagtaag gatgcgatta tttaactggc gccgtcaggc
    20281 gattttacat gctatgccgg tggtaaaacc cgaccagata cgcacgccgt ggcgggagtt
    20341 ctggcgtcgt tttcgccgcc agcatgtcgc gttggtcgcc gggggattcg tactggcgtt
    20401 aattctggtg gcgatttttg cccgttggct aacgccctac gatgcggaaa actattttga
    20461 ctacgatagc ctgaacaatg gcccctcttt gcagcattgg tttggcgttg actcgctggg
    20521 aagagacatc tttagccggg ttctcgttgg cgcgcagatc tcactggcgg cgggcgtgtt
    20581 cgcggtattt atcggcgcga taatcggcac ggtgttggga ttgctggcgg gatattatga
    20641 aggctggtgg gatcgtttca ttatgcgcat ttgcgatgtg ttgttcgcct tccccggcat
    20701 tttgctggcg attgccgttg tggcggtgtt aggcagcggt attgctaatg tgatcgttgc
    20761 ggtggcgatt ttctctattc cggcgtttgc tcgtctggtg cgcggaaata ccctggtctt
    20821 aaaacagcag acgtttattg agtctgcccg cagtatcggc gccagcgaca cgacgatttt
    20881 gtttagccac atcttgccgg gaacggtctc gtcaattgtg gttttcttta cgatgcgtat
    20941 cggtacgtca attatttccg cggcaagcct gtcatttctc gggttaggcg cgcagccgcc
    21001 aacgccggag tggggagcga tgcttaatga agcgcgggcg gatatggtca tcgcgccgca
    21061 cgtggcgctc ttcccggcgg tggcgatttt cctgactgtg ctggcgttta atctgttagg
    21121 cgacgggttg cgcgatgcgc tggacccgaa gattaagggg taagccagcc cggtggcgtt
    21181 gacgcctggc gggcctggaa ccggctcgcc aggtggggta acacattcgg cacccgcgcc
    21241 gggggaagtg gcgttaaacc cgactgcccc acaaatcata ttcgtcggcg ttttccactt
    21301 tcacgcgcac gatatcgccc ggcttgacgt tggtttcgcc gttcaaatag accgcgccgt
    21361 caatttccgg cgcatccgcc atgctacgcc cgatagcgcc ttcttcgtca acctcatcga
    21421 cgatcaccag aatttcgcgg cccacttttt cctgcaagcg ctcagcggag atttgctgtt
    21481 gcagttgcat aaagcggttc cagcgctctt ctttcacctc ttccggcacc tgatccggca
    21541 gctcattcgc gcctgcgcct tccaccgggc tgtacttgaa gcagcctaca cgatcgaggc
    21601 gcgcctcttt caggaagtcg agcagcatct ggaagtcttc ttccgtttcg ccggggaagc
    21661 cgacaataaa ggtggagcgt agggtcagtt ccgggcagat ttcgcgccac tgcttaatgc
    21721 gcgccagctg gcggtcaacg gaaccaggac gtttcatcag tttaagaatc cgcgggctgg
    21781 catgttgcag cggaatgtcc agataaggca ggattttgcc ttccgccatt agcggaatca
    21841 catcatcaac gtgtgggtag gggtagacgt agtgcagacg tgtccagacg cccagttttg
    21901 ataactgctc gcacaggctc accatactgg ttttcatcgg ttcgccatta tggaatccgg
    21961 tgcggtgctt cacatctacg ccgtaggcgg aggtatcttg cgaaatcacc agaatctctt
    22021 tgaccccggc atcaaccaga cgtttcgctt cgcttaatac gtcgccaatc ggacggctga
    22081 ccagatcccc gcgcatcgac gggatgatgc agaacgtgca gcggtgatta cagccttcag
    22141 aaattttcag atacgcataa tggcgcggcg tcagttttac accctgttcc ggtacgaggc
    22201 ttaaaaatgg attgtgcttc ggcttcggta cgtaatgatg tacgtgctgc agaacttgct
    22261 catagctatg cggcccggtg atttccagta ctttcggatg cacttcgcgg atctgatctt
    22321 cttttgcgcc caggcagccg gtgacgatta ccttaccgtt ttcgttcagc gcttcgccaa
    22381 tggcttccag tgactcttgt accgcgctgt caataaagcc acaggtatta acgataacca
    22441 tatccgcatc gtcatagtgt ggcacaacgt catagccttc ggtacgcagc tcagtcagga
    22501 ttcgttccga atcaacgagg tttttcggac agcccaggga aacgaagccg atctttggct
    22561 ggtgggttac attactcata gcttaaaaag tgttcattta ttggaatggt cagggcaggg
    22621 attctacaga tatccgaaca aaaattgtat cgcaatctca tcaggagcgg cggcatcaac
    22681 cgttgtggtt atcagcaaaa ggtgaaaaag ggcaattcta agaaaattct tgatctctga
    22741 cacccctttg tctaaaaaac gaccatacta ttaagttgaa ccctggtaga aaagaggagg
    22801 aaaaaaggta tggtcgttga cagactgaga accgatcttc tcaacaagct gataaacgcg
    22861 cgtatcgatc ttgccgctta tctgcaattg cgaaaagcga aggggtatat gtcagtcagc
    22921 gaaagtgaca ctctgcgtga caattttttt gaactgaatc gcgagctcca cgatcacgct
    22981 ttacggcagg gactgcatct cgatcaggaa gagtggaacg cgctgcgccg tgccgaaggc
    23041 gcgcttgcag ccgccgccgt ttgtttaatg agtggacacc atgattgtcc gacctttatt
    23101 gccgtcaacg cagataaact tgaaaactgt ctgacaactt tgacgctgag tattcagagt
    23161 ctgaaagcac attcaccgct tacacaggtc tgaataaggg ggaggcgact cccccttttt
    23221 accggaccgc gccgcttaat gttttgtaaa aataaacccg acctcttgcg atgctgacta
    23281 cgctttaacg cagagccctg aaggaggcgg tatgcgtcga atacttctcg cgatagtttc
    23341 attctctctt ttctcttcat gggcgaacgc caatcttgcg ccggtgaacg ttgaggtgct
    23401 gcaaacccga ctcgatcacc cgtggtcgct ggcttttttg ccggataacc gtgggatgct
    23461 cattaccctg aaagggggac aactgcgcca ctggcagacg gggcggggac tttccgatcc
    23521 gctggctggc gtaccgaaag tgtgggcaaa cgggcaggga ggtttgctgg acgtcgtgct
    23581 ggcgcctgat tttgcccagt cgcgccgcgt ctggctgagc tatgctgaag ctgaccgcga
    23641 aggaaacgcc ggtacggcag ccggctttgg acggctgagc gacgattttc agcgtctgga
    23701 gcattttcgt accgtgtttc gccagatgcc taagctgtct accggcaacc atttcggcgg
    23761 acgtatggta ttcgatgcgc aagggtttct ttttattgcc ctgggtgaaa ataaccagcg
    23821 cgctaccgcg caggatttgg ataaattaca gggtaagctg gtgcgcctga ccgggcaggg
    23881 cgaaattccg ccggataatc cgtttgtaca tcaggcgggc gcgcgtccgg aaatctggtc
    23941 ttacggtatt cgtaatccgc aggggctggc catcaatccc tggagcggcg cgctatggct
    24001 gcatgaacac ggtccgcgcg gcggcgatga aattaacatc ccggaaaaag gcaaaaatta
    24061 tggctggccg ctggccacat ggggcgtcaa ctatagtggt ctgaaagtgc cggaagccaa
    24121 aggtgaaatt gtcgagggaa cggagcaacc ggtttactac tggaaggatt ctccggcgat
    24181 cagcgggatg gctttttatg ccagcgacgt ttttgcgccg tggcggcaca aactgtttat
    24241 cggcgcgcta aaagataaag aggtcattgt gatgcgcgtc gatggcaata cggtgacgga
    24301 agaaggccgt attctgggtg acagaaagca gcgtattcgg gatgtgcgtg tcggacctga
    24361 cggctactta tatgtgttaa ccgatgagtc cgacgggcag ttactcaagg taagtcctgc
    24421 agccacgcgt taggtcaccg ggatcatcac cactttgcga aaagcagggc gctcggtaag
    24481 ctgttgatac cagcgttgca gattcgggcg cggcgtccac ttcagaccca cgttcagcag
    24541 gttatagacg aagggcgcaa tagcgatatc gccggtgcca aagttatccc ctgagaacca
    24601 cggctggtgg gccagcgcat catcaagaag cgcaaacagg ctatcacact tttcgatacc
    24661 ggcttcaatt gccgcctggt cgcgtttttc cggcggggtt ctgaccagtc ccatcaggat
    24721 cacgcggtgc gccgggctta acgtttgatt cgcccagtcc atccattttt cgccctccgc
    24781 acgccgtgcc ggattatcaa cccatagccg gttctggccg tattgcgccg ccagatagcg
    24841 gacaatggca ttggattccc acaataacag gtcggtttca tcatctttaa gcagcggcac
    24901 cagcccatta ggattcatcg ccagatagtc ggcatcctgg ttaacgccga attttccacc
    24961 tgccagaatt tgatcgtatg gcagttccag ctcttcaagc gtccacaaca cttttttaac
    25021 attagtcgag ttgttccggc cccacagcgt aatcatatta accccttctg ttttatcagg
    25081 atgatgacag taatcggcct accgtgagat aaacctaaca tttacacaat ggtctgtaaa
    25141 aaaatcgtta tgaaggaagc gtaacgggat gttattgcat aaactttaaa aactttacca
    25201 agttacggtt tctttaacgt cgtgagtgcg ttattactca ccgcacttat tacacggtgg
    25261 tgtgacgtgt gtttttggaa tggatactcg ggtggtacta tgacgcaata cgcttcttcc
    25321 cttcgtagcc tcgcggcagg ttcggttctc ttattccttt tcgcttcgcc tgtaaaggca
    25381 gaggaacaaa cgatcgcgcc gccgggcgtt gatgcgcgag cctggatctt aatggattac
    25441 gccagcggta aagtactggc ggaaggcaac gccgatgaga aactcgaccc tgccagtttg
    25501 acaaaaatta tgaccagcta cgtggtgggc caggcgctga aggcaggcaa aatcaagctg
    25561 accgatatgg tgacggtggg caaagatgcc tgggcgacgg ggaacccggc gctacgtggg
    25621 tcgtcggtga tgtttctgaa gcccggcgat caggtgtcgg ttgcggatct taataaaggc
    25681 atcatcattc agtcaggtaa tgatgcctgt atcgcgcttg ccgactacgt cgccggaagc
    25741 caggagtcct ttatcggcct gatgaatgcc tatgcgaaac gattggggtt aaccaataca
    25801 accttccaga cggtacacgg ccttgatgcg ccagggcagt tcagtaccgc tcgcgatatg
    25861 gcgctgctcg gcaaggcctt gattcacgat gtgcctgacg aatacgccat tcataaagag
    25921 aaagaattta cttttaataa tattcgtcag ccaaaccgca accgcctgtt gtggagtacc
    25981 aatctgcatg tcgacggcat gaaaacgggg acaacggcag gcgctggata taaccttgtc
    26041 gcctccgcca cccagggcga tatgcgcctg atctctgtcg tgctgggggc gaaaacggac
    26101 cgtattcgtt ttaatgagtc agaaaaactg ctgacctggg gtttccgctt ctttgaaacg
    26161 gtcacgccga ttaaacctga cgcgacattc gtgacgcaac gggtctggtt tggcgataag
    26221 cgtgaggtca atttgggagc gggcgatgcg gggtctgtga cgattccgcg tgggcagctt
    26281 aaaaacctga aggccagctt tacgttgaac gaaccacagc tcacggcgcc attgaagaaa
    26341 gggcaggttg tcggcaccat cgatttccag cttaacggaa aatccattga gcaacgcccg
    26401 ttaatggtga tggaaaacgt cgaggagggg ggatttttca gccgtatgtg ggattttgtg
    26461 ctgatgaaac tccatcagtg gtttggcagt tggttctcgt aaaataaccc cgttgccggg
    26521 tgcgcgtcgc atccggcaaa cctgcggtta atacatcaga gtaatttgtt gcgctttagc
    26581 gtaggccaca aaggcctcat cgggacggcg gtcgctgata atcgtatcaa agcgtgataa
    26641 ttcccccatc cgcgccggac gtaccttgcc gaatttactg tgatccacca ccagtacatg
    26701 gctctgggcc attgtcatgg cccaatgttt taccggcagc tcttccagat taaagcaggt
    26761 agcgccttta ctggtatgaa cgccggcggc ggaataaaac gcgatatccg gacaaatatt
    26821 gtttaacgtt tcatggaaat caagcggttt gaaaatggcg ttgctggcgt gaaactcccc
    26881 gccgctgagg atggcgcggc aatggggttt gtcctgcagc gccagaaagg tattaagtga
    26941 atagcacacc gccgtaaagg gaagatcatt atcaatagct tcaatgatcc acggcgtggt
    27001 ggtgccgcag tcaataaata ccgtctgatg cgcttgtacc aagcccgcag ccaactgagc
    27061 ggcacggcgt ttttcttcca ccagacgaga tttttgatcg cttaacagat aatgactggc
    27121 gctgcggggc tccagtacga tatagccgcc cagcaacacg acaggcgcgc ttttatggtt
    27181 caggtcgcga cgaatggtca tttcagagac gcccaacagg gtcgcggctt ctttaagatg
    27241 aagtttatcg ctgcgtttta aggcctgcag caattgacca atacgctcgt cgcgtcgcgt
    27301 ttccatagtt cccctggaga gttaaataag cgctccgcac catacagagc gcttaatatt
    27361 actctttttt tcgctattta gtcacgtacc cagccttttc gaatgggcaa tgcgaaacag
    27421 aaacggtaac aacgttgcag cgcctggtag agcggcgcgc cgtaccattg ccagatcagc
    27481 tgtgcgctca ggcagccaag catcgctacc agcagcgcgc caatcatatc taacggccag
    27541 tgtacgccga gatagacgcg cgaccaggcg atggtcatgg ctatcgccat catcacgatg
    27601 cctgaccaga ggcggtgcca gaacaaaaac gccagcgcaa aggtaaaaat caccgtaccg
    27661 tgatcgctgg ggaacgagtc atcggcggca tgatgcagga agttatagcc gatatgatcg
    27721 acaaacggac ggtcgtgcgg gaaaaggtgt cccattgtcc aggagaccgc cagactgata
    27781 atcagcgcga tgccgatttt aacgatcagc tggcgctggg cgcagacccg atcgcggggc
    27841 ccccacagcc agagtaccac ggctaagagc gggacgatgt tgatgacatc tttggcgata
    27901 aagatagcga gcgaaattat ccactgcgcg gaatcaggcg tggcgttaat aaaataaaac
    27961 agcgagttgt taaggttttc cagcataaca tccaggctcg gagcaatgaa atcaaaaggg
    28021 atagccagct catccccgtg caaactgagc ataaatgcag cgtaacaggg aggaaaagca
    28081 gtattgtctt atttggcggc aacatgaaga gatttaagac aatggcataa aataacgttg
    28141 atgataacgg cgcaaactta aattaacctt aaagtacgca agcgctaagc agctttctgt
    28201 aaaaatgtgc gctatttccc ttgcagcctc ataattcgct atctcagttc cccgactttc
    28261 attacactct gcgcggtttt tattggcgaa gagatggtat gcagaatcgt ttacaatcag
    28321 gcggcaggct gggacgtcag gcgctgcttt ttcctctctg tctggtgctg tacgagtttt
    28381 ctacttatat tggcaacgac atgatccaac cgggtatgct ggcggtggtt gagcagtatc
    28441 aggcgggcct ggactgggtt ccgacgtcca tgaccgctta tctggcgggc ggtatgttct
    28501 tacaatggct gcttggcccg ttgtctgacc ggattggccg tcgtcccgtg atgctggcgg
    28561 gcgtcgtgtg gtttattgtc acctgcctgg cgacgttact ggcgaaaaac atcgaacaat
    28621 ttacattcct gcgttttttg caagggatta gcctgtgttt tatcggcgct gtagggtatg
    28681 ccgcgattca ggaatccttt gaggaggcgg tgtgtataaa aattaccgcg ctgatggcga
    28741 acgtggcgtt aatcgcgccg ctactgggac cactagttgg ggcggcatgg gtgcatgttc
    28801 tgccgtggga ggggatgttt attttatttg ccgcactggc cgctatcgcc tttttcgggc
    28861 tacagcgcgc aatgccggag accgccacgc ggcggggcga aacgctgtca tttaaggcgc
    28921 ttggccggga ttatcggctg gtgataaaaa atcggcggtt cgtcgcaggg gcgttagcgc
    28981 tgggatttgt cagcctgccg ctgttggcct ggattgcgca gtcgccgatt atcatcatta
    29041 gcggcgaaca gctcagcagc tatgaatatg gtttgctgca ggtgcccgtt tttggcgcgc
    29101 tcattgccgg taatctggtg ttggcgcgtt taacctcccg acgtacggtt cgctcgctga
    29161 tcgtgatggg cggctggcct atcgtcgcgg ggctgatcat cgccgcggcg gcgacggtgg
    29221 tttcatccca tgcttattta tggatgacgg cgggattaag cgtatacgct tttggcattg
    29281 ggctggcgaa tgccggactg gtgcgtctga cgctcttttc cagcgatatg agtaaaggaa
    29341 cggtctcggc ggcgatggga atgctacaaa tgctgatttt taccgttggc attgaagtca
    29401 gtaaacacgc ctggttaagc ggcggcaatg ggctatttag cctgtttaat ctggcaaacg
    29461 gtattctttg gctactgctg atgctggtct tcttaaaaga taagcggacg gggaatttgc
    29521 aaacagtctg agagagcggc tacgcctgat aagctttctg ttatcaggcg tagagaggca
    29581 tccgctagac gttgaacggc ggctcgttgt ttaatacgct gtcgatgata tccagcacgc
    29641 cttcctgatt gttcgatccg gcgcggtatt tcgccgccgc cgcgaccgct tcgctggcgt
    29701 gcgacatggc aaaactaaac ccggcctgac gcagcatctc aatatcgttg ccgccgtcgc
    29761 cgaataccac cacttcacta tcatgaatgc cccagcgctg ctgtaacaga cgcaggccgt
    29821 tggctttatg cacgccggga attattaaat caatactgcc atagccggta tgaacgggga
    29881 ccatgatatc gccaatggcg tcgtgcagcg ccgcctgtac ttccggtatc cgttcatcgg
    29941 taatattaag gccgaatttg aaaaaaacat cgctgatatt gttgaaatta tccacaaact
    30001 ccagacgatg ataatacatt gccgcaacgg cttttaacgc atcgtcgtac cgtttcagcg
    30061 tgtaggcgct gttttttcca caggcgatga tctccacatc ggcgcgtgtg agcaggtgtt
    30121 cgacaaccgc ctggaagtcg gcttttgcca gctcgccgtt aaaaacatcc tctccttcgc
    30181 tgaccaccca gccaccgttt tccgcgacaa aagcgatttc gtgcgcaatt tccggaaaga
    30241 aggagattaa ctggtaatac tggttgccgc tggccacgac aaagcgaatg ccttgccgct
    30301 tcatttgttg gtactgcgcc ataaaccggt cacggttata ggttttttga tcgctcagaa
    30361 aagtgccgtc catgtcgacg gcgattaatt taatactcat gcgttatgct ccatcaccgg
    30421 ttgcggagtc gatacaggtt tggcgacggc cttcgccacc agcgctgcca gaataaccag
    30481 cgccagcaca accatcatgg cgctgcgtaa tccatagtgc tctcccagat agcccaacag
    30541 cggcggcccg accaaaaacg ccagatagcc ggtcgtggcg acaacgctca cgcgcgtcgg
    30601 cgcgtcggga ccggtatcgc tggcggcgga aatggtcagc gggaagccga gcgaagcgcc
    30661 taagccccaa agaatgaccg agacgccggc aacccagtcg ctatcgacaa aaataatcag
    30721 gccaatgccc aacgctccca tcaacgcgct ggcgcgaaca accgtcaccc ggctatagcg
    30781 gtcaataaac cagccgccgg taaagcggcc aacggtcata ccaagcgtga aaccggcgta
    30841 gatcagagag ccggaggttg ggctaaaacc gtgtccgtct accatcagta gcggtagcca
    30901 gtcattcgca gatccttcgg cgaatgccat tgccagcacc accacgccaa taagcaaaag
    30961 ctggatgtcc cgataaaaag gtaatccttt ttcctgaagg tgagaacctt ccgatgcgtt
    31021 tttacccgta ccgtcaggga tcgcccgaat ggcgataaaa atgggcgcga tcgccacggc
    31081 agccgcgagg atgatatgga tgttagccgg gacgcttaat gcggttaacg ccatgccgac
    31141 accagcgccc gccagcgtgc cgaaactgta gaaaccatgc atcatcggca gaacggtttt
    31201 attcagctcg cgttcgaccg ccgcgccttc gacattaatc gccacttcgg cggcgccaaa
    31261 actggcgccg aaaacggcta atccaagggc aaaaatcagc ggcgaggcgc accacagcgc
    31321 gacgctaaga ataaccatcc cggttactgc gcaggtcatc gtcgtgtgaa taaccttccg
    31381 ggtgccaaat cgtttcacca gccaggcgga acaaagaata ccgctcattg aaccgataga
    31441 aagcccgaat aagaccgtcc ccatttccgc ggtagagacg gaaagaatat cccgaatagc
    31501 aggcgttcgg gttgcccagg aggccatcag cagtccgggt aaaaagaaga acataaacag
    31561 cgcccaggta cggcgtttta aggcgttacg tgaggagagg acggtcatag cgtcaggcca
    31621 gaaaatagaa gcgagaggta aacattagca agcttgtgta catttgtaca tatcgtcgtc
    31681 atacttcgtt gtgcagacag tttttgctgt ctgttttttc agcgtaagcg gcaggctact
    31741 atcgcctgca tcctgaatga gatgtggaac tcatcatgaa agaaaatgcc gtaagacgcg
    31801 ccaatgatcc taagcgacgg gaaaaaataa ttcaggccac actggaagcg gtaaagacct
    31861 atggcgttca tgccgtgacg caccggaaaa tcgccgctat cgctcaggtg ccgcttggct
    31921 cgatgaccta ctattttgcc ggtatggatg cgttattgag tgaagctttt acacttttca
    31981 ccgagaacat gtcgcgtcaa taccaggatt tttttgcgca ggtgacggat gtggaggggg
    32041 cgtgccaggc gataacggaa atgatttacg gctcgcaggt tacgacgccg gataatatgg
    32101 cgttaatgta tcagttatat gcctatgcca gcgataagcc agcgttaaaa atagtcatgc
    32161 aaaactggat gcagcgtagc cagaatacgc tggcgcagtg gtttgacgca cagaccgccc
    32221 gcgcgctgga tgcgtttatc gaggggatga cgctgcattt tgtgacggat cgaacgccgt
    32281 tggcgcgtga agcgatttta cagatggtaa agcgaatagc cggagagtca atgtcgtgtc
    32341 actctgcgtc gggcaacaaa aaacccacca accttgaacc gaaatggcgg ggttgatggg
    32401 ctccacaaaa tggggacatc aaagaaaagc agtggcaata ggtatgactg atgctttaac
    32461 gaaaagttcg acctattggc aaaatttttt cacttaaagg caaacttcag ttttatccta
    32521 atcccggcca gatgatgaca ataagcgtcc ccgccagcgt tagcagaacg ttggcgatgg
    32581 cgtaagtccc cgcataaccc agcgctggaa tattgctgcg cgctgtatcg ctaatgattt
    32641 ccatcgccgg ggcgcaggta cgcgcgccca tcatggcgcc gaacagcagc gcccggttca
    32701 tgcgcagcac ataagcgcca aacaagaagc agatcaccac cggtatcagg ctgacgacaa
    32761 gcccggcgat cagcatttgt ccgccgaccg cgcccagacc gttgctgata ccgctgccgg
    32821 cgcttaaacc aacgcctgcc ataaatacca tcaagccgaa ttctttcacc atgttaagcg
    32881 cgccctgcgg aatataacca aaggtaggat ggttagcgcg caggaaaccg agcatgatcc
    32941 cggcgaacag caatccggcc gcgttgccga tgccgaaact aaaatttctg aactggaagg
    33001 taatcatccc gatcattaac ccgatgataa aaaaagcgca gaaggcgagc aggtccgtca
    33061 cctgactatg gatcgaaata aaaccaatgc gatcggcgat ggtttttacg cgtctgacgt
    33121 cgccgctcac ctgtaacacg tcgcctttat tcagcacgac gttatcgtcg ataggcattt
    33181 cgatctggct gcggatgacg cggttaagga agcagccatg atcggtcagc ttgagctgag
    33241 cgaggcggcg accgaccgca ttgtggtttt tcaccacaat ttcctccgtc acgatgcgca
    33301 tatcaagcag atcgcgatca aacacttcct taccattacg gaagctggga tcgagcctgg
    33361 cgtgcgcgtc cggatagccg accagcgcaa tctcatcgcc catttgcagc accgcatcgc
    33421 catccgggtt cgccagaata ccgttacgac gaatacgttc gatatagcag cctgtctggc
    33481 ggtaaatacc cagctcgcgc aggtttttac cgtcagtcca ggccaccagt tccgggccaa
    33541 cccgataggc gcggataacc ggcaaataaa ccttgcgatt agcatcggta tccagaccgc
    33601 gctcgcgagc aatttgctgg gcgctggttt gcaaatcctg atgctgtagt ttaggcaagt
    33661 aacgcgcgcc cacgatcaga ctgaccagcc caatcagata ggtcagggca tagcccaggc
    33721 tcagattatc aagagcggag gagagttggg tgctggcgat gccggaatgt cgcagggtat
    33781 cgcctgcgcc aaccagcacg ggcgtggatg tcattgagcc ggccagcata ccggccgtca
    33841 ggccgatatc ccagccgaat agcttaccaa ggcctaaggc gattagcaga gcgctaccga
    33901 ccatgaccag ggcaagcatc agataatttt taccgtcgcg aaaaaaaatc gaaaaaaagt
    33961 tggggccagc ctcgacgccg acacaaaaaa taaacagcat aaatcccaga tttagcgcgt
    34021 cggtgttaat actaaagtgt tgctgcccta ataatagaga gaccactaaa acgccaatgg
    34081 aattaccaag ttggactgaa cccagacgta acttgccaag acacaggcca agagccagga
    34141 ccacaaataa taacaggatg taattcccat ttaacaaatc tgcgacgttt atattcacgg
    34201 agactaactt cttgtttacg agtaagctgt tgaaagaaat ggtaatttac gctactgttt
    34261 ttatcatgaa ttaagggtgc aatcgtattg catacagcat ccaaataaaa acaacacaac
    34321 aatatatcct gctagtttaa tcttattgcg tactaacggc tataagaatt gtgcaggtgt
    34381 gtttttggca tggaatgcca catgacttta tctgactgga tgcctcacgg cggaaagcgt
    34441 gttcgataga gagtgtcagg aggaacggtt gaaacataaa cacgggtggg caagcgttgt
    34501 ctgctgcttt gtactcttta ttgtggtgtg tctttcatta actatgcatg tacaaggcgc
    34561 ttttcgcgcg gcagggcatc ctgagattgg actgttattt tttacgttgc ttggtgcggt
    34621 ggccagtttt tgttctcacc gacgcgaggt gatccgaccg ctgatcgggg cgatgctggc
    34681 ggcgccgttt tgcctggtgt taatgcgcgt ggtatttatg cctacccgat cgttttggca
    34741 agaactggcg tggttattta gcgccgtatt ctggtgtgcg ttaggcgcgc tctgctattt
    34801 gtttattagc agcctgttta gccaccggcg aaaaaaacgc cgatagcgcc ctccggcaga
    34861 gggcgtcgcc agagcaatca ggcgaaaaga ttcagatttt cttttgccca tgcttcaaaa
    34921 tccgtacagc cgccgatatg tttttgatcg acaaaaatct gcggtacggt ttctacaggt
    34981 ttacctacgg ttttttccaa atccgcttta gtaatgcctt cggcatggat atcaatatag
    35041 cggtagttga aatcgtcgcg ttctttgctc agtttttccg ccaactcttt tgcacgcacg
    35101 caataagggc accctgggcg gccaaaaata acagtaaaca tatctctcct cgaacataaa
    35161 gccagacggc gaacaggtgt tatcatgccg cgatttacgg cagatgaaaa gcaggttacg
    35221 cctgttcctt tgataactca gggctatatc tgttaagcac gccggaccag aacgttctac
    35281 actgtgcgtc agttaaccgg gaggcttgat atgcgcacga tcggcgtgtt acccaaaagc
    35341 gtactgatac tggaatgcct cggtatgatt ttgctggcgc ttgctctgct atcgcttaat
    35401 cattacctta cgctgcccgc gccgttcaat acgtcgctgg ctggcgtatt gatggttttc
    35461 ctgggcgtcg tgttgatcct ccccgccgcg gtggcgatga tgtggcgtat tgcgcagtta
    35521 ctggcgccgc agttgatgaa acgtccaccc gacatttctt cccgttcaga tagagaaaag
    35581 cataatgagt ccgaccattg aacttctttg tggccatcgt tctattcgcc atttcaccga
    35641 tgaacccgtg actgacgcgc agcgagaggc cattattgcc gccgcgcgca gcacgtccag
    35701 ttccagtttt ttacagtgca gctctataat ccgtattacc gatcgggcgc tgcgcgaggc
    35761 gttagtgccc ctgacgggcg ggcaaaagca tgtggcgcag gccgctgagt tctgggtatt
    35821 ttgtgccgat tttaatcgtc atttgcagat ctgtcctgac gcgcagttgg ggcttgccga
    35881 acaactgctg ctcggtgtcg tcgatacggc gatgatgggg caaaacgcgc tgacggcggc
    35941 ggaatcactg gggttaggcg gcgtgtatat cagcggcatc cgtaataata ttgaatctgt
    36001 taccgaacta ttaaaattgc cgaagcatgt attgccgctc tttggcctgt gtttgggatg
    36061 gcctgcggat aatccggatc tgaaaccgcg cctgcctgcc gagcttgtgg ttcatgagaa
    36121 ccagtatcaa ccgcttgatg aaaagctgct ggcgcgctat gacgagcagt tggctgagta
    36181 ttatctgacc cgcggcagta atacgcgacg cgatacctgg agcgatcata tccgtcgcac
    36241 cctgattaaa gaaaatcgcc catttatcct tgaatatttg cataaacagg gctgggcgac
    36301 gcgctaaaac ctgcgggcca gtgtatgata cgcgggcttt tcagggtttt cagcgaggtg
    36361 cagggtgaaa attgccatat tgtctaggga tggaacgctc tattcttgca aacgtctgcg
    36421 cgaagcggcg atgcggcgcg gccatctggt cgagatactc gatcctcttt cctgctatat
    36481 gaatattaat ccggcagcgt cgtcgatcca ttacaagggg cgtcgtctgc cccattttga
    36541 cgccgttatt ccccgtattg gttcggccat taccttttat ggtaccgctg cgctacgtca
    36601 gtttgagcta ctgggtagct atccgctgaa tgaatccgtc gctattaccc gcgcgcgcga
    36661 taagctgcga tcgctacaac ttctggcgcg ccaggggatc gatctcccca ttaccgggat
    36721 cgcccattcg ccggatgata ccagcgatct tattaagatg gttggcgggg cgccgctggt
    36781 cgtgaagctg gtagaaggca cgcaagggat cggcgtggta ttggcggaga cgcgtcaggc
    36841 tgctgaaagc gttattgatg cgtttcgggg gctgaatgcc catatcctgg ttcaggaata
    36901 cattgccgaa gctaaaggat gcgatattcg ttgtctggtc gtcggcaatg aggttgtggc
    36961 ggcgattgag cggtgcgcga aagccggtga ttttcgctcc aatcttcatc gtggcggggt
    37021 ggccagcatc gcgacgatca cgccccgtga acgggatatc gccatcaaag ccgcacagac
    37081 gctggggctg gatgtggcgg gtgtcgatat tttacgcgcc gcgcgcgggc cgctggtgat
    37141 ggaggtgaat gcctcgccgg gactggaagg tatcgaaaag actacgggcg tggatatcgc
    37201 ggggcgaatg attcagtgga tagaacgtca cgctacgcct gaattttgcc ttaaaatcgg
    37261 cggctaatcg caatcgtgga ttccgccgta gtacgaagca cgctttttgc gtaagctgtg
    37321 ccggtaattt tttcatcgtc atcgtaagag gtagcacatt attatgatat cactggtcgt
    37381 tcccactctg gatacgttgc gtcaatggct cgacgacctg ggcatgaatt tcttcgaatg
    37441 tgatacctgc caggcgctgc atttgccgca tatgcagaat tttgacggcg tctacgatgc
    37501 taaaatcaat ttggtggaca acaccgttct tttttccgcg atggcggagg tcaggccttc
    37561 cgcgttgctg ccgctggcgg ccgatctctc tgctatcaac gccagttcgt tgacggtaaa
    37621 agcctttctc gatatgcagg atgataatct gccaaaactg gttgtgtgcc agtctttatc
    37681 cgttatgcaa ggcgtcacct acgagcagtt cgaatggttt gttcgccaaa gtgaagagca
    37741 gatttctatg gtgatccttg aggccggggc gcatcagctt ctgtttaacg cggaagaaga
    37801 cgcgcaaaaa accagcgcgg ttgaccattt tcttcactga tccctcccga taatcaggca
    37861 gtcgctgcca gcgcggctgc tgtttacgtt tttttatgct gctgttaacc tttatttaaa
    37921 gaattattca cctcctttct ggccatttcg ctttatcaca tagacaaaac ctgcataaaa
    37981 aattgataaa aggcgttttt taatctgggc tatagcctca aaccttagct aaagttattc
    38041 ttgcgaagct tctatagcga gcttgatggc agggagggcg acctctcttc ttcatttgta
    38101 tcaaatgaaa aggtatgcac atttcaggca tgttttaaac cacgcctaat gggttcattt
    38161 gttaacggat tttagaagga aagcgatgat gaccgcctta aagaaaaaat ggctatcggg
    38221 tctggttgcg ggtgctctga tggtcgtctc tgtcggcacg ctcgctgccg aacaaaaaac
    38281 gctgcacatt tataactggt cagattatat cgcgccggac acggtggcga actttgaaaa
    38341 agagaccggg attaacgtta tctatgatgt ctttgactct aacgaagtgc tggaaggcaa
    38401 gttaatggca ggcagcaccg ggttcgatct ggtggtgcca tcggccagtt ttcttgagcg
    38461 ccagctcacc gcgggcgttt ttcagccgct ggataaaagc aaacttcccg gctggaaaaa
    38521 cctcgatcct gaactgctga aactggtagc gaagcacgat cctgacaaca aatacgccat
    38581 gccctatatg tgggccacga cgggcattgg ctataacgtt gataaagtga aagcggtgct
    38641 gggggatgat gcgccagtga atagctggga tttagtcctc aagccggaaa atctggagaa
    38701 gctaaaaagc tgcggcgtct ctttccttga tgcgcctgaa gaaatttttg ccaccgtgct
    38761 gaattatctg ggtaaagatc cgaatagcag caaagcggat gactacaccg gcccggcaac
    38821 cgatctgttg ttgaagctac ggccaaacat tcgctatttc cactcctcgc aatacattaa
    38881 cgatctggct aatggcgata cctgtgtggc catcggctgg gcgggcgatg tctggcaggc
    38941 cgctaaccgg gcgaaagagg cgaaaaatgg cgtcaatatc tctttctcga tccccaaaga
    39001 gggggtaatg gcattttttg atgtgtttgc catgccggct gacgccaaaa ataaagacga
    39061 ggcctaccag ttccttaatt atctgctgcg ccttgatgtg attgctcata tttccgatca
    39121 cgttttctac gccaatgcga ataaagaggc gacggcgctg gtcagccagc aggtgcgcga
    39181 taacccagga atttatccgc cggcggatgt gcgggccaag ttgtttaccc tgaaagtgca
    39241 ggagccgaag attgatcgcg tccgcacccg cgcatggacg aaggtgaaaa gcggtaagta
    39301 atttattaac ggtatggcct gataagcgtg cgctatcggg cattccaccg tttgtatcgt
    39361 ttgattgtgt tatgccggag agcgccttgt gaatgatgcc ccccaccgcc cgcaggtgaa
    39421 aacccgtaaa gcgctgacgc cgcttctgga aattcgcaac ctgacgaagt cattcgacgg
    39481 gcaacatgct gtcgatgatg tcagtctgac tatctataaa ggtgagattt ttgccctgct
    39541 gggcgcgtca ggttgtggaa aatcgactct gttacggatg ctggcgggtt ttgaaccgcc
    39601 gagcagcggg caaattatgc tcgacggcgt cgatctggcg catgttccgc cgtatcagcg
    39661 tccgattaat atgatgtttc agtcctatgc gttgtttccg catatgacgg tagagcagaa
    39721 catcgctttt ggtctgaagc aggacaaact gccgaaggcg gagattacca gccgcgtcaa
    39781 tgagatgctg ggtctggtgc acatgcagga gtttgcaaaa cgtaagccgc atcagctttc
    39841 cggcggtcag cgtcagcgcg tggccctggc gcgcagcctg gcgaaacgtc ttaagctgct
    39901 cttgttggat gaaccgatgg gcgcgctgga taaaaaatta cgcgaccgga tgcagctgga
    39961 agtggtggat atccttgagc gcgtcggcgt gacttgcgtc atggtgacgc acgatcagga
    40021 agaagccatg acgatggcgg ggcgcattgc catcatgaac cgtggaaaat ttgtgcaaat
    40081 tggcgaaccg gaggagattt acgagcatcc gacaacccgc tatagcgccg aatttatcgg
    40141 atcggtaaat gtttttgagg gcttactgaa agcgcgtgaa gaggacggtc tggtcattga
    40201 cgcgcccggt ttggttcatc cgttaaaagt cgatgcagat gcctctgtcg ttgataatgt
    40261 gccggtatat gtggcgctac gtccggaaaa aatcatgctg tgtgagtcgc cgcctgccga
    40321 tggctataat ttcgccgtcg gcgaagtggc gcatattgcg tatctcggcg atctgtctat
    40381 ttatcatgtg cggctaaaaa gcgggcagat gatcagcgct caactgcaga atgcgcaccg
    40441 ttaccggaaa gggttaccga cctggggcga tgaagtgcgt ttgtgctggg aagcggatag
    40501 ctgcgtggtc ctgacggtat aagggggaaa catgagcaca cttgaacctc cggcacgcat
    40561 cagtaaacct ggcggcgcgg cgctatggtt ggcgcgaatg caaatgaaac atgggcgtaa
    40621 gctggttatt gctttgcctt atatctggct cattctgctg tttttactgc cgtttcttat
    40681 cgtctttaag ataagcctgg cggaaatggc gcgggcgatc ccgccgtata ccgatctgct
    40741 ggaatgggct gacggtcagt tgtcgattac gctcaacctc ggcaattttt tgcaactgac
    40801 cgacgatccg ctctatttcg aagcctgtct gcaatcgtta caaattgccg gtatttccac
    40861 aatctgctgc ctgctgctgg gctacccgct ggcgtgggcg gtggcgcaca gcaagccctc
    40921 cacgcgcaat atcctgctgc tgttggtgat tctgccctcg tggacgtctt ttttaatacg
    40981 cgtctatgcc tggatgggca ttttgaaaaa caacggtgtg ctgaacaatg tgttgctgtg
    41041 gctaggggtt atcgatcagc cgctgacgat cctgcacact aacctggccg tctatatcgg
    41101 cattgtttat gcgtatctgc tgtttatggt tctgcccatt tataccgcgt tgacgcgcat
    41161 tgattattcg ctggtggaag cgtcgctgga tctcggcgcc cgaccgatga aaacattttt
    41221 tagcatcatt gtcccgctca ccaaaggcgg aatcatcgcc ggctcgatgc tggtttttat
    41281 cccggcggtg ggcgagttcg tgatcccgga actgcttggc gggccggaca gtatcatgat
    41341 tggtcgcgtc ctgtggcagg agtttttcaa taaccgcgac tggccggtgg cttctgcggt
    41401 cgccattatt atgttgctgc tgctgatagt cccgatcatg tggttccata aacatcagca
    41461 aaaaagtgtg ggggagcacg gatgaataac ttaccggtcg ttcgctcgcc ctggcgcatt
    41521 ctgattctgg tgctggggtt tacttttctc tatgcgccga tgttaatgtt ggtgatttac
    41581 tcgtttaaca gttcgaagct ggtgacggtg tgggcgggat ggtcgacgcg ctggtatggc
    41641 gagctctttc gggataccgc catgatgagc gcagtgggac taagcctgac aattgccgcc
    41701 tgcgcggcga cgatggcggt ggtgctcggt actatcgccg cggtggtgat ggtgcgattt
    41761 ggacgatttc gcggcgcaaa cggctttgcg tttatgatca ccgcgccgct ggtgatgccg
    41821 gatgtgatta ccgggctgtc gctgctgctg ctgtttgtcg cgctcggtca tactatcggc
    41881 tggccctccg atcgcggaat gctgaccatc tggttggcgc acgtcacttt ctgtaccgcc
    41941 tatgtggcag tggtgatcgc ttcgagatta cgcgaactgg atcgttcgat tgaagaggcg
    42001 gcgatggatc ttggcgcggc gccgttgaag gtcttttttg tcattacgtt accgatgatc
    42061 atgccagcgg tgatctcggg ctggctgttg gcctttacgc tctcccttga cgatctggtg
    42121 attgccagct tcgtttccgg tcccggcgcc accacgctac cgatgctggt tttctccagc
    42181 gtgcgcatgg gtgtgaaccc ggaaatcaac gcgctggcga cgttaatcct cggcgtggta
    42241 ggaatcatcg gatttattgc ctggtacctg atggcgcgag cggaaaaaca gcggattcgc
    42301 gatatccagc gtgcaagacg cggctgaagc cactaaaatc ttccactatg gcaatgcgtt
    42361 gccgcgcgag tcgcggcatc attttcaggg aagacattca ttgggattta taaagcaatc
    42421 aacctcatca catgcccgtt taaatgtgcc tacgctggtg caggttgcgg ctatggcgat
    42481 tattttgatt cgcggtctcg atgtgctgat gattatgaat accctcggca tacgcgggat
    42541 gggcgagttt attcatcgca gcgtgcagac gtggagctta accctggtct ttctggccag
    42601 cttagtgctg gtctttattg aaatttattg tgcgttttcg ctggtgaaag gccgtagctg
    42661 ggcgcgctgg gtgtacctgg cggcacaaat tattgtgagt gggtatctgt gggcggcgtc
    42721 gttaggctac gggtatccgg agttgtttag catcgcggga gaatcgaagc gtgatatcct
    42781 gcattccctg gtcatgcaaa aactccccga tcttttaatt ctgtttctgc tgtttattcc
    42841 cgctcccagc cgtcggttct tccggctgca ataatgtgta taatcgtcac cccggataat
    42901 atgaaggttt tttggtatgc agtgcgcact ctatgacgcg ggtcgctgcc gttcctgtca
    42961 atggattacg cagtcggtta acgaacaact ttccgcaaaa acagccgatt tacatcgttt
    43021 gctggccggg ctgcctgttg aacagtggtg cgcgccgatt agcggcccgg aacagcattt
    43081 ccgcaacaaa gcgaaaatgg tcgtgagcgg tagtgtagaa aaaccgctct tcgggatgct
    43141 gcatcgcgac ggtacgccgg tcgatctttg cgcttgcccg ctgtatcccg cctcctttgc
    43201 ccccgtattc agcgcgctaa aaccttttat tgcccgtgcc ggactcacgc cttataacgt
    43261 ggcgcgaaaa cgcggcgaac tgaaatacct gttgctgacg gaaagtcagt tcgatggcgg
    43321 catgatgcta cgcttcgtgt tgcgttcaga aaccaaactt acgcaactgc gcgcggcgtt
    43381 accgtggctg cgcgcgcaac tgccgcagct cagagtgatc accgcgaata tccagccggt
    43441 acatatggcg attatggaag gggagacgga aatctatctg acggatcagc aggcgctggc
    43501 ggaacgtttt aacgatgtgc cgctgtggat tcgtccgcaa agtttctttc agaccaaccc
    43561 tacggtcgcc agccgattat atgcgacggc gcgcgactgg gtagggcaat tgccggtacg
    43621 ccatatgtgg gatctttttt gcggagtggg cggattcggc ctgcactgcg cgacgccgca
    43681 gatgcaatta accggtattg agatcgcgcc ggaggcgatt gcctgcgcga agcaatccgc
    43741 tgccgagctg ggattaaccc gccttcattt ccaggcgctg gattccaccc aattcgccac
    43801 cgcacaaggc gaaacgcccg atctggtgtt ggtgaatcct ccccgccgcg gcattggcaa
    43861 gccgttgtgc gattaccttg cacaaatggc gccgcgtttt atcatttatt cgagctgtaa
    43921 cgcgcagacg atggcgcagg atattcgcca tctgccgaac taccgtattc aacgtgttca
    43981 gcttttcgat atgttccccc ataccgcgca ttatgaagtg ttaacactgc tttgcaggct
    44041 gtagc
//
LOCUS       DAJVKX010000026        43954 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.026, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000026 DAJVKX010000000
VERSION     DAJVKX010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 43954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43954
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.026"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            52..1287
                     /locus_tag="OPY25_001387"
     CDS             52..1287
                     /locus_tag="OPY25_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HCS0927038.1"
                     /translation="MSVYKVPLEQNVLEAAQERITWTLETLPRVCVSFSGGKDSGLML
                     HLTATLARKMNKKIHVLFIDWEAQFSCTIAYIESLREYYADVIERFYWVALPLTTQNS
                     LSQYQPEWQCWQPGTDWVRQPPEDAITDPAFFSFYQHGMTFEQFVRDFADWFSEKRPA
                     AMLVGIRSDESYNRFVAIANSHKLRFADDKPWTTLAPKGHTWYIYPIYDWKTADIWTW
                     FAKTGKSCNPLYNLMYQAGVPVRYMRICEPFGPEQRQGLWLYHVIEPERWAAMYARVS
                     GVLSGGIYAGQDSHFYGHRKILKPDHLNWEEYALLLLHSMPEVTAEHYRNKIAVYLQW
                     YKKKGMNTIPQTQQGDIGSRDIPSWRRICKVLLNNDYWCRALSFSPTKPKSYQRYNER
                     MKAKRQEWGILCNTDSQPK"
     gene            1260..1877
                     /locus_tag="OPY25_001388"
     CDS             1260..1877
                     /locus_tag="OPY25_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HCS0927039.1"
                     /translation="MQHRLTTEITHFLSGLPEEERIAAINEFRRAIHNVSPFRDEPVD
                     CVLWVKNDHISPNDYNPNNVAPPEKKLLLKSIEKDGFTQPIVVVKANTEEYEIVDGFH
                     RHELGKGKAVLKRRLKGYLPVACLDRERHERMAATIRHNRARGRHQIHAMSEIVRELS
                     QLGWDESKIGQELGMDADEVLRLKQINGLQELFADRRFSRAWTVK"
     gene            complement(1878..3038)
                     /locus_tag="OPY25_001389"
     CDS             complement(1878..3038)
                     /locus_tag="OPY25_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCS0927040.1"
                     /translation="MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDG
                     PSYLHERLAYHVAQGANQYAPMTGAQALREAIADKTAEIYGYRPDDVSDITVTAGATE
                     ALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
                     SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASV
                     LAHPQLRERAVAVSSFGKTFHMTGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLA
                     LADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTYFLLIDYSAVSTLND
                     VEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL"
     gene            3165..4253
                     /locus_tag="OPY25_001390"
     CDS             3165..4253
                     /locus_tag="OPY25_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCS0927041.1"
                     /translation="MNHTEIRVVTGPANYFSHAGSLERLTDFFTPEQLSHAVWVYGER
                     AIAAARPYLPEAFERAGAKHLQFTGHCSERHVAQLAHACNDDRQVVIGVGGGALLDTA
                     KAHARRLALPFVAIPTIAATCAAWTPLSVWYNDAGQALQFEIFDDANFLVLVEPRIIL
                     QAPDDYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINSACAIRDLLLTSSEQALA
                     DKQQRRLTQAFCDVVDAIIAGGGMVGGLGERYTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLITAYRRFHLPTRLSELDVDIHNTAEIDRVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVEFFRI"
     gene            complement(4289..4486)
                     /locus_tag="OPY25_001391"
     CDS             complement(4289..4486)
                     /locus_tag="OPY25_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HCS0927042.1"
                     /translation="MFDTLSKAGKYLGQAAKMMIGVPDYDNYVEHMRITHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(4550..6655)
                     /gene="cstA"
                     /locus_tag="OPY25_001392"
     CDS             complement(4550..6655)
                     /gene="cstA"
                     /locus_tag="OPY25_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HCS0927043.1"
                     /translation="MNKSGKYLVWTALSVLGAFALGYIALNRGEQINALWIVVASVCV
                     YLIAYRFYGLYIAKKVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGATAG
                     VIVLVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLAIFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAASPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGDLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFAITPDTLHQIANEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKIGFLAIANKFQAMIDSG
                     NIPPQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLAVFSIKTALAALKIDKPTANETP
                     YEPMPENVDEIVTQAKGAH"
     gene            complement(6837..7250)
                     /gene="entH"
                     /locus_tag="OPY25_001393"
     CDS             complement(6837..7250)
                     /gene="entH"
                     /locus_tag="OPY25_001393"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HCS0927044.1"
                     /translation="MIWKRHLTLDELNATSQNTLVAHLGIVYTRLGDDVLEAEMPVDA
                     RTHQPFGLLHGGASAALAETLGSMAGYLMTRDGQCVVGTELNATHHRAVSQGKVRGVC
                     LPLHLGRQNQSWEITLFDEQGRRCCTCRLGTAVMG"
     gene            complement(7253..8008)
                     /gene="entA"
                     /locus_tag="OPY25_001394"
     CDS             complement(7253..8008)
                     /gene="entA"
                     /locus_tag="OPY25_001394"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HCS0927045.1"
                     /translation="MASFDFSDKTVWVTGAGKGIGYATALAFVDAGARVIGFDREFTQ
                     ENYPFATEVMDVADAAQVAQVCQRVLQKTPRLDVLVNAAGILRMGATDALNVDDWQQT
                     FAVNVGGAFNLFSQTMAQFRRQQGGAIVTVASDAAHTPRIGMGAYGASKAALKSLALT
                     VGLELAGCGVRCNVVSPGSTDTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARP
                     QEIANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(8008..8865)
                     /locus_tag="OPY25_001395"
     CDS             complement(8008..8865)
                     /locus_tag="OPY25_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase"
                     /protein_id="HCS0927046.1"
                     /translation="MAIPKLQSYALPTALDIPTNKVNWAFEPERAALLIHDMQDYFVS
                     FWGRNCPMMDQVIANIAALRQYCKEHHIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVEALTPDEADTVLVKWRYSAFHRSPLEQMLKDTGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSREEHLMALNYVAGRSGRVVMTESLLPTPIPASKAAL
                     RALILPLLDETDEPLDDENLIDYGLDSVRMMGLAARWRKVHGDIDFVMLAKNPTIDAW
                     WALLSRGVE"
     gene            complement(8879..10489)
                     /gene="entE"
                     /locus_tag="OPY25_001396"
     CDS             complement(8879..10489)
                     /gene="entE"
                     /locus_tag="OPY25_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HCS0927047.1"
                     /translation="MRIPFTRWPDEFARRYREKGYWQDVPLTDILTRHADSDKTAVIE
                     GERAFSYRQLNQAADNLACSLRRQGIKPGETALVQLGNVPELYITFFALLKLGVAPVL
                     ALFSHQRTELNAYAMQIAPTLVIADRQHTLFAGEDFLNRFVAEHRSARVVLLRNDDGD
                     HSLDAAMRQAAEGFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSNEIC
                     GFNEETRFLCAIPAAHNYAMSSPGALGVFLAKGTVVLATDPGATLCFPLIEKHQINAT
                     ALVPPAVSLWLQAIQEWGGNAPLASLRLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSPERIINTQGRPMCPDDEVWVADADGNPLPPGEIGRLMTRGPYTFR
                     GYFNSPQHNVSAFDANGFYCSGDLISIDQDGYITVHGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIHAALVSMEDELLGEKSCAYLVVKEPLRAVQVRRFLREQGVAEFKLPDRVE
                     CVASLPLTPVGKVDKKQLRQRLASRSPL"
     gene            complement(10499..11674)
                     /gene="entC"
                     /locus_tag="OPY25_001397"
     CDS             complement(10499..11674)
                     /gene="entC"
                     /locus_tag="OPY25_001397"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HCS0927048.1"
                     /translation="MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAV
                     AGDSPDSPFQQKLRQQFAEAKSQGIANPVLVGAIPFDTRQPSSLFIPMAWQSFSRQQK
                     QRTARYFTDHQPLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV
                     AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARR
                     QPDDVLDREAGDRLLASQKDRHEHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWH
                     LGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWC
                     DAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH"
     gene            11982..12938
                     /gene="fepB"
                     /locus_tag="OPY25_001398"
     CDS             11982..12938
                     /gene="fepB"
                     /locus_tag="OPY25_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HCS0927049.1"
                     /translation="MRLSAFYRWLLLVVGLSISGISLAQDAGWPRQIQDSRGVHTLDH
                     KPARIVSTSVTLTGSLLAIDAPVVASGATTPNNRFADDQGFMRQWSDVAKARHVARLY
                     IGEPNAETVAAQMPDLILISATGGDSALALYDQLSAIAPTLVINYDDKSWQSLLTQLG
                     EITGQEKQAAARIAEFEAQLTTVKQRIALPPQPVSALVYTPAAHSANLWTPESAQGKL
                     LTQLGFTLATLPQGLQTSKSQGKRHDIIQLGGENLAAGLNGESLFLFAGDNNDVAALY
                     ANPLLAHLPAVQNKRVYALGTETFRLDYYSATLLLNRLAALF"
     gene            complement(13001..14245)
                     /gene="entS"
                     /locus_tag="OPY25_001399"
     CDS             complement(13001..14245)
                     /gene="entS"
                     /locus_tag="OPY25_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HCS0927050.1"
                     /translation="MNRQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFIGLMVGGVLADRYERKKVILLARGTCGIGFIGLCVN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMLGGILLASGGVAWNYGLAAAGTFITLLPLLTLPRLPVPPQPRENPFIALLAAFR
                     FLLASPLIGGIALLGGLVTMASAVRVLYPALAMSWQMSAAQIGLLYAAIPLGAAIGAL
                     TSGQLAHSVRPGLIMLVSTVGSFLAVGLFAIMPIWIAGVICLALFGWLSAISSLLQYT
                     LLQTQTPENMLGRMNGLWTAQNVTGDAIGAALLGGLGAMMTPVASASVSGFGLVIIGL
                     LLLLVLGELRRFRQTPPVSDAG"
     gene            14356..15363
                     /gene="fepD"
                     /locus_tag="OPY25_001400"
     CDS             14356..15363
                     /gene="fepD"
                     /locus_tag="OPY25_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HCS0927051.1"
                     /translation="MSCSFSVTRAFAVPGLLLLLSLAAVLSLVIGAKPLPAAVVLEAF
                     TGVCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGILGVNNGAS
                     FAIVLGAALFGFSTPLEQLFMAFSGALIASLIVAFTGSQGGGQLSPVRLTLAGVALGA
                     VLEGLTSGIALLNPEVYDQLRFWQAGSLDIRSLQTLKVALAPVVIAGIVALFLSRALN
                     SLSLGSDTATALGSKVARTQLIGLLAITVLCGSATALVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRLLVPGELRVSVVSAFIGAPVLIFLVRRKSSGGG
                     L"
     gene            15363..16352
                     /gene="fepG"
                     /locus_tag="OPY25_001401"
     CDS             15363..16352
                     /gene="fepG"
                     /locus_tag="OPY25_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HCS0927052.1"
                     /translation="MFLSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLETGQIIAALLG
                     DAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSG
                     VLVAMVLFGQHLTAIALAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAF
                     NTWLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIMVMLTGAALLVRRMRLLEM
                     GDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGTARWG
                     LTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            16349..17143
                     /gene="fepC"
                     /locus_tag="OPY25_001402"
     CDS             16349..17143
                     /gene="fepC"
                     /locus_tag="OPY25_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HCS0927053.1"
                     /translation="MTESVARLRGDQLTLGYGSYTVAKNLNVSIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPVDGHVWLDGEQIQRYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDADAVASAMRATGITSLAAQSVDTLSGGQRQRAWIAMVLAQ
                     ETSIMLLDEPTTWLDISHQIDLLELLSDLNREKGYTLAAVLHDLNQACRYATHLIALR
                     EGNIVAQGAPKEIVTAELIEKIYGLRCMIIDDPVAGTPLVVPLGRR"
     gene            complement(17196..18332)
                     /gene="fepE"
                     /locus_tag="OPY25_001403"
                     /pseudo
     CDS             complement(17196..18332)
                     /gene="fepE"
                     /locus_tag="OPY25_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459581.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
     gene            complement(18582..22466)
                     /gene="entF"
                     /locus_tag="OPY25_001404"
     CDS             complement(18582..22466)
                     /gene="entF"
                     /locus_tag="OPY25_001404"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HCS0927054.1"
                     /translation="MTQRLPLVAAQPGIWMAEKLSDLPSAWSVAHYVELNGELDAPLL
                     AKAVAVGMQQADTLRMRFTEENGEVWQWIDPEHTFGEPPIADLRDQPDPHLAALALMQ
                     ADLRQNLRADSGKPLAFHQLIRIDDTRWYWYQRYHHLLVDGFSFPAITRQIAAIYRAW
                     QSDAPTPESPFTPFVDVVEEYQRYRQSEAWQRDGAFWAQQRRELPPPASMSAAPLPGR
                     SASADILRMKLSAPAGAFRQLAAHMPEIPRADLALALVTLWLGRLCGRMDYAAGFIFM
                     RRMGSAALTATGPVLNVLPLAVNLHATEDLPTLAKRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGETPLFGPVLNIKVFDYHLDFPGIQAQTHTLATGPVNDLELALFPDENGGLDI
                     ELLANAQRYDDATLSRHALRLMALITQFADNPALRCGDAQMLLAEEQTQLTHLNNTAV
                     TIPAATLSDLVAQQAQKTPEASALADAHYHFTYREMREQVVALAYALRERGVQPGDSV
                     AVALPRSVFLTLALHGIVEAGAAWLPLDTGYPDDRLRMMLEDAQPKLLITTQAQLARF
                     HDIPGMEYLCYSQPLPVSDATPLGLSLPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQDHYPLTADDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQRFF
                     AQYGVTTTHFVPSMLAAFIASLTPASAGKSCASLKRVFCSGEALPTALCREWETLTNA
                     PLHNLYGPTEAAVDVSWYPACGDELAAVDGNSIPIGYPVWNTGLRILDAHMQPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDSGVVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQTLPDVEQAVAHACVFNQAAATGGDARQLVGYLVSHSG
                     LPLDLPALQDKLRQKLPAHMVPVVLLQLASLPLSANGKLDRKALPLPDLTPRVKGRAP
                     QSATEIAVAAAFSRLLGCEINDVESDFFALGGHSLLAMKLAAQLSQTFNRQVTPGQVM
                     VASDVAQLSKLLDTDDDERSRNLGFGPLLPLRESDGPTLFCFHPASGFAWQFSVLSRY
                     LSPSWSIMGIQSPRPVGPMQIATTLDEVCEHHLATLLARQPHGPYYLLGYSLGGTLAQ
                     GIAARLRARGETVAFLGLLDTWPPETQNWRGKEANGLNPDVLAEIERERAAFVAAQQG
                     NASDALFTAIEGNYADAVRLLTTAHSAPFDGHATLFVADKTVPEDVSPEQSWSPWIAS
                     LAIYRQPCAHVDIISPSAFETIGPIISELINK"
     gene            complement(22463..22681)
                     /locus_tag="OPY25_001405"
     CDS             complement(22463..22681)
                     /locus_tag="OPY25_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbtH family protein"
                     /protein_id="HCS0927055.1"
                     /translation="MEFSNPFDNPQGQFYILQNAQRQFSLWPAACALPAGWGVVCEPQ
                     SQDACQQWLNTRWTTLNPAHYADKQEAK"
     gene            complement(22712..23926)
                     /gene="fes"
                     /locus_tag="OPY25_001406"
     CDS             complement(22712..23926)
                     /gene="fes"
                     /locus_tag="OPY25_001406"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HCS0927056.1"
                     /translation="MKEALATGSEAWWRTKTGPEWIREKDGNYRVTFWWRDPQGNETH
                     SPIRRVWVYITGVTDHHQNAQPQTMARIAGTDVWRWSTALSANWRGSYCFIPTERDDV
                     FAAFAPGETPDRNALREGWRQLLPQAIADPLNSQSWRGGRGHAVSALEMPDAPRQPGW
                     DRPETSYSPPLMMQWHSERLGNSRRVWILTTGDEATEERPLAILLDGQFWAENMPVWP
                     ALASLTHQRLLPGAVYLLIDAIDTQHRNQELPCNADFWLAVQQELLPQVRAVTPFSDD
                     AGRTVVAGQSFGGLSALYAGLNWPTRFGCVLSQSGSFWWPHRITPPEGEVITRLKTGA
                     LCARGLRIVLEAGVREPIVFQANQALYAQLNTSQQSIFWRQVDGGHDALCWRGGLTQG
                     LMLLWQPLIDTL"
     gene            24115..26370
                     /locus_tag="OPY25_001407"
     CDS             24115..26370
                     /locus_tag="OPY25_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HCS0927057.1"
                     /translation="MNKKIHSLTLLVNLGIYGAALPVMAEEKTDSAALTNEDTIVVTA
                     AQQNLQAPGVSTITADEIRKNPPARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRG
                     MGPENTLILIDGKPVTSRNSVRLGWRGERDTRGDTAWVPPEMIERIEVLRGPAAARYG
                     NGAAGGVVNIITKKGGSEWHGSWNTYFNAPEHKDEGATKRTNFSLNGPLGGDFSFRLY
                     GNLDKTQADARNINQGHQSERTGSYADTLPAGREGVINKDINGVVRWDFAPLQSLELE
                     AGYSRQGNLYAGDTQNTNTNQLVKDNYGKETNRLYRQNYSLTWNGGWDNGVTTSNWVQ
                     YEHTRNSRMPEGLAGGTEGIFDPKASQKYADADLNDVTLHSEVSLPFDLLVNQNLTLG
                     TEWAQQRMKDQLSNSQTFMGGNIPGYSSTNRSPYSKAEIFSLFAENNMELTDSTMLTP
                     GIRFDHHSIVGDNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYATGAGTGIGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGT
                     VPLQRINNGKTDVYQWKNVPKAVVEGLEGTLNVPVSDTVNWTNNVTYMLQSKNKETGE
                     RLSIIPQYTLNSTLSWQVRQDVSLQSTFTWYGKQEPKKYDYQGNPVTGTDKQAVSPYS
                     IVGLSATWDVTKNVSLTGGVDNLFDKRLWREGNAQTVRDTQTGAYMAGAGAYTYNEPG
                     RTWYMSINTHF"
     gene            26417..27121
                     /gene="entD"
                     /locus_tag="OPY25_001408"
     CDS             26417..27121
                     /gene="entD"
                     /locus_tag="OPY25_001408"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HCS0927058.1"
                     /translation="MLTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGR
                     KRKAEHLAGRIAAVHALREVGVRAVPGIGDKRQPLWPDGLFGSISHCASTALAVISRQ
                     RVGVDIEKIMSQHTATELAPSIIDSDERQILQASSLPFPLALTLAFSAKESVYKAFSD
                     RVTLPGFDSAKITSLNATHISLHLLPAFAAMMAERTVRTEWFQRGNSVITLVSAITRF
                     PHDRSAPASILSAIPR"
     gene            27133..28251
                     /locus_tag="OPY25_001409"
     CDS             27133..28251
                     /locus_tag="OPY25_001409"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HCS0927059.1"
                     /translation="MALNDFHVSEPYTLGIELEMQVINPPGYDLSQDSSTLIDAVKPQ
                     LTAGEIKHDITESMLEMATGVCRDIDQVAAQLSAMQHVILQAASEHHLGICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCANGDDAIYLLHGLSHFVPH
                     FIALSAASPYMQGSDTRFACARLNIFSAFPDNGPMPWVSNWQEFAGLFRRLSYTTMID
                     SIKDLHWDIRPSPAFGTVEVRVMDTPLTLDHAINMAGLIQATAHWLLTERPFKPQEQD
                     YLLYKFNRFQACRYGLEGVLTDVYTGDRRRLADDTLRLLDNVTPSARKLGADSAIDAL
                     RLQVKKGGNEAQYMREFIADGGSLIGLVQKHCEIWAGQ"
     gene            28318..28566
                     /locus_tag="OPY25_001410"
     CDS             28318..28566
                     /locus_tag="OPY25_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 family protein"
                     /protein_id="HCS0927060.1"
                     /translation="MKHPLESLMTAAGILLMALLSSLLLPAPSLGLALAQKLVGIFHL
                     MDLNQLYTLLFCLWFLLLGTLEYYVIRFIWRRWFSLAD"
     gene            complement(28572..28913)
                     /locus_tag="OPY25_001411"
     CDS             complement(28572..28913)
                     /locus_tag="OPY25_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RamA family antibiotic efflux transcriptional
                     regulator"
                     /protein_id="HCS0927061.1"
                     /translation="MTISAQVIDTIVEWIDDNLNQPLRIDDIARHAGYSKWHLQRLFM
                     QYKGESLRRYVRERKLKLAARDLRDTDQKVYDICLKYGFDSQQTFTRIFTRTFNLPPG
                     AYRKEKHGRTH"
     gene            29202..29783
                     /locus_tag="OPY25_001412"
     CDS             29202..29783
                     /locus_tag="OPY25_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCS0927062.1"
                     /translation="MARPKSEDKKQALLEAATQAIAQSGIAASTAVIARNAGIAEGTL
                     FRYFATKDELINTLYLHLKQNLCQSMIMELDRSITDAKTMTRFIWNSYISWGLNHPAR
                     HRAIRQLAVSEKITKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE
                     TTMDFAARDPARAGEYIALGFEAMWRALTREEQ"
     gene            29783..30151
                     /locus_tag="OPY25_001413"
     CDS             29783..30151
                     /locus_tag="OPY25_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCS0927063.1"
                     /translation="MDGQTLHACAKRFALELPFTEHCWPFGPQYDVFKVGGKIFMLFT
                     EHHCRPVVNLKSAPQKSLVNQQIYPSIAPGYHMNKKHWISVYAGEDITVSLLNDLIND
                     SWNLVVDGLPKREQLRLRPR"
     gene            30248..30901
                     /gene="nfsB"
                     /locus_tag="OPY25_001414"
     CDS             30248..30901
                     /gene="nfsB"
                     /locus_tag="OPY25_001414"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HCS0927064.1"
                     /translation="MDIVSVALKRYSTKAFDPSKKLTAEEADKVKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYTFNERKMLDASHVVVFCAKTAMDDAWLQRVVDQE
                     DADGRFATPEAKAANDKGRRFFADMHRVSLKDDHQWMAKQVYLNVGNFLLGVAAMGLD
                     AVPIEGFDAEVLDAEFGLKEKGYTSLVVVPVGHHSIEDFNAGLPKSRLPLETTLTEV"
     gene            31101..31226
                     /locus_tag="OPY25_001415"
                     /pseudo
     CDS             31101..31226
                     /locus_tag="OPY25_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459569.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
     gene            complement(31256..33226)
                     /locus_tag="OPY25_001416"
     CDS             complement(31256..33226)
                     /locus_tag="OPY25_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HCS0927065.1"
                     /translation="MTQKRTLLKYGILSLALAAPLSACAFDSLTVIGDSLSDTGNNGR
                     WTWDSGQNKLYDEQLAERYGLALSPSSNGGSNYAAGGAMTAPELNPQDNTADQVRQWL
                     ANTGGKADHNGLYIHWVGGNDLAAAIARPAMAQQIAGNSATSAAAQVGLLLDAGAGLV
                     VVPNVPDISATPELLEAVITAGLGAAAPPALKAALEALAEGATPDFASRQQAIRKALL
                     AAAATVSSNPFIQQLLVEQLLAGYEKVAEQASALTDYYNQMEEKGLEQHGGNIARADI
                     NGLFKEILANPQAFGLTNTVGMACPPGVSASVCSSAMPGFNASQDYLFADHLHPGPQV
                     HTIIAQYIQSIIAAPVQATYLNQSVQSMAQGSRTTLDSRYQQLRQGENPVGSLGMFGG
                     YSGGYQRYDNNEADGNGNHNNLTVGVDYQLNEQVLLGGLIAGSLDKQHPDDNYRYDAR
                     GFQAAVFSHLRAGQAWLDGDLHYLSAKFSNIQRSITLGALRRVEEGETNGRLWGARLT
                     SGYDFVMMPWLTTGPMLQYAWDYSHVNGYSEKLNTSTSMRFGDQNAHSQMGSVGWRLD
                     LRHSIIHSWAQINYRRQFGDDTYVANGGLKSTALTFSRAGKAQDKNWVDIAIGADFPL
                     SATVSAFAGLAQTAGLSDGNQTRYNVGFSARF"
     gene            33537..34784
                     /locus_tag="OPY25_001417"
     CDS             33537..34784
                     /locus_tag="OPY25_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCS0927066.1"
                     /translation="MQELISQVEDLAGIEMNHTTSLVVIFGIIFLTAVVVHIILHWIV
                     LRAFEKRASASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAALWLQKGSEAADILTTC
                     AQLWIMTYALLSLFSLLDVIFNLSQKWPAASQLPLKGIFQGIKLIGAIIVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSINIDATSIHF
                     LDDDEKQRLLTAQLLKPYLTSRHQEIDEWNKQLDAPESALNHRRMTNIGTFRAYLNEY
                     LRHHPRIRKDMTLMVRQLAPDDHGLPIEIYAFTNTVVWLEYESIQADIFDHIFAVVEE
                     FGLRIHQTPTGSDIRALSGTLRH"
     gene            complement(34826..36220)
                     /gene="pheP"
                     /locus_tag="OPY25_001418"
     CDS             complement(34826..36220)
                     /gene="pheP"
                     /locus_tag="OPY25_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HCS0927067.1"
                     /translation="MKNASTASGASVSDAASKNEPTLQRGLQNRHIQLIALGGAIGTG
                     LFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAWKYWGPF
                     AGFLSGWNYWVMFVLVGMAELTAAGIYMQYWLPDVPTWVWAAVFFIIINAVNLVNVRL
                     YGETEFWFALIKVLAIIGMIGFGLWLLFSGHGGEHASIDNLWRYNGFFATGWHGLLLS
                     LAVIMFSFGGLELIGITAAEARDPQKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVE
                     VKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPK
                     FLTRVSHRGVPVNSLMLSGAITSLVVLINYLLPQKAFSLLMALVVATLLLNWIMICLA
                     HLRFRAAMRRKGRETQFKALFYPAGNYLCIAFLALILVLMCTMDDMRLSAILLPVWIV
                     FLFIAFTVLRRKAH"
     gene            36546..37721
                     /locus_tag="OPY25_001419"
                     /pseudo
     CDS             36546..37721
                     /locus_tag="OPY25_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459559.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(37800..38360)
                     /locus_tag="OPY25_001420"
     CDS             complement(37800..38360)
                     /locus_tag="OPY25_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgB family protein"
                     /protein_id="HCS0927068.1"
                     /translation="MDKYLRLLSQGDRLGLTLIRLSIAIVFIWIGLLKFVPYEADSIT
                     PFVANSPFMSFFYEHPEEYRQHLTHEGELKPEERAWQTANNTYAFSDGLGVVELIIAA
                     LVLANPVSRWLGLAGGVLAFLTPFVTLSFLITTPEAWVMPLGDAHYGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSARSLLLQRQ"
     gene            complement(38373..38609)
                     /locus_tag="OPY25_001421"
     CDS             complement(38373..38609)
                     /locus_tag="OPY25_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0927069.1"
                     /translation="MLKVTTLIASLLAAPLAFSASAQPLTDVEYISVSAVSATPSMLE
                     DAIARLAQSKQASSWKITSMRIDNTGYATAILYK"
     gene            complement(38766..40091)
                     /locus_tag="OPY25_001422"
     CDS             complement(38766..40091)
                     /locus_tag="OPY25_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HCS0927070.1"
                     /translation="MTQYQALIIGFGKAGKTLAATLAKTGWRVAIIEQSASMFGGTCI
                     NIGCIPTKTLVYDAEREGDFSVAMQRKAAVVNFLRDKNFHNLADLDNVDVIEGRAEFI
                     DNHTLRVFQADGERVLRGEKIFINTGAESVIPAITGLTTTAGVFDSTGLLSLSQRPAR
                     LGILGGGYIGLEFASMFANFGTKVTIFEAAPQFLPREDRDIAQAITHILQEKGVELIL
                     NANVQAVSSTEGAVQVETPEGAHLVDALLVASGRKPATAGLQLQNAGVAVNERGGIIV
                     DDYLRTTADNIWAMGDVTGGLQFTYISLDDFRIVRDGLLGDGKRSTRDRQNVPYSVFM
                     TPPLSRVGLTEEQARASGATVQVVTLPVAAIPRARVMNDTRGVLKAVVDVNTQRIVGV
                     SLLCVDSHEMINIVKTVMDADLPYTVLRDQIFTHPTMSESLNDLFSLIK"
     gene            40307..41161
                     /locus_tag="OPY25_001423"
     CDS             40307..41161
                     /locus_tag="OPY25_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCS0927071.1"
                     /translation="MDALSRLLTLNAPQGSIDKNCPLGGDWQLPHAAGELSVIRWHTV
                     TQGEAQLEMPTGDAMTLTPGKVVILPQNSAHRLRQSGEAPTHIVCGSLRLHTTSRYFL
                     TALPEVLCLAPPPHSPASIWLNAAISLLQQESERHLPGADVLYSQQCATLFTLAIRDW
                     LSQAGTAKSVLNLLLHPRLGRVILHMLETPAHPWTVETLVQRVHMSRASFAQLFRDVS
                     ATTPLAVLTTLRLQIAAQTLSREALPVMVIAESVGYASESSFHKAFVREFGCTPGEYR
                     KRVNALGR"
     gene            complement(41212..41424)
                     /locus_tag="OPY25_001424"
     CDS             complement(41212..41424)
                     /locus_tag="OPY25_001424"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927072.1"
                     /translation="MPGLYRGLPLYAGGREQRDKNDRKGAGSEVMSRIATPMIGGMIT
                     APLLSLFIIPAAYKLMWLRRHRRLAA"
     gene            41328..41523
                     /locus_tag="OPY25_001425"
                     /pseudo
     CDS             41328..41523
                     /locus_tag="OPY25_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000635961.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
     gene            41655..41966
                     /locus_tag="OPY25_001426"
     CDS             41655..41966
                     /locus_tag="OPY25_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-binding protein"
                     /protein_id="HCS0927073.1"
                     /translation="MNKFTSLLAVVFISAGVHTAEKMESRQLSATAHEMMNNGDAFAH
                     QQMAQTQKPSAPTTVENATPFSEMDDYEKAMVIHQSMNNAHSFSHEIQAEEHHKQIKR
                     N"
     gene            42369..42731
                     /locus_tag="OPY25_001427"
     CDS             42369..42731
                     /locus_tag="OPY25_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCS0927074.1"
                     /translation="MLKLFAKYTSIGVLNTLIHWGVFAFCVYGMHTHQALANFSGFVI
                     AVSFSFYANARFTFNASTTTLRYMMYVGFMGTLSAVVGWMADKCSLPPLLTLVTFSAI
                     SLICGFIYSKFIVFRDAK"
     gene            42728..43654
                     /locus_tag="OPY25_001428"
     CDS             42728..43654
                     /locus_tag="OPY25_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCS0927075.1"
                     /translation="MKISLVVPVFNEEATIPIFYKTVREFEELKPYEVEIVFINDGSK
                     DATESIINKIAASDPLVIPLSFTRNFGKEPALFAGLDHATGDAVIPIDVDLQDPIEVI
                     PHLIEKWQAGADMVLAKRSDRSTDGRMKRKTAEWFYKLHNKISNPKIEENVGDFRLMS
                     RDVVENIKQMPERNLFMKGVLSWVGGKTDVVGYARAERVAGDSKFNGWKLWNLALEGI
                     TSFSTFPLRIWTYIGLFIAGMSFLYGTWMIIDKLIFGNNVPGYPSLLVSVLFLGGVQL
                     IGIGILGEYIGRIYIETKKRPKYIIKNGKKNG"
     gene            43635..>43954
                     /locus_tag="OPY25_001429"
     CDS             43635..>43954
                     /locus_tag="OPY25_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927076.1"
                     /translation="MGRKMVNNRLKMVIAILIVFSLVYSIGFITPMNSDDYTYALREL
                     SLSSVKMHYLGWSGRVVSDTLSTSLLKFFSPHIYNAINSAALTLMVLCWTMIPATLTK
                     SSPSP"
BASE COUNT        10493 a        12434 c        11269 g         9758 t
ORIGIN      
        1 tgttaattat tgcgaatata ttgtagttaa cacattggag actatccaga gatgtcggtt
       61 tataaagttc cgcttgagca aaatgttctg gaagcggctc aagagcgtat aacatggacc
      121 ctggaaactt taccccgggt ctgcgtctca ttttctggtg gtaaagattc aggacttatg
      181 ctgcacctga cggcaacgtt ggcgcgcaaa atgaataaaa agatccacgt tcttttcatt
      241 gactgggaag cgcaattctc ctgtactatc gcttatattg aatcgttacg tgaatactac
      301 gcggacgtta ttgagcgttt ttattgggtc gcattaccct taaccacaca aaattccctt
      361 tcacaatacc agccggagtg gcagtgttgg cagccgggaa ccgactgggt acgacaaccg
      421 ccagaagatg cgattaccga tccggccttt ttttcctttt atcaacacgg catgactttt
      481 gaacagttcg ttcgcgattt tgccgactgg ttttcagaaa agcgccctgc cgctatgctg
      541 gtcggtattc gttccgacga atcctataac cggtttgtcg ctatcgctaa ctcgcataag
      601 ctgcgctttg ccgacgataa gccctggacc acgttggccc ccaaggggca cacctggtat
      661 atctacccca tctatgactg gaaaaccgca gatatctgga cctggttcgc caaaacaggt
      721 aaatcatgta accccttgta taatttgatg tatcaggctg gcgtaccggt ccgttacatg
      781 cgtatttgcg aaccattcgg cccggaacaa cggcaggggt tatggctgta tcatgttatc
      841 gaacctgagc gctgggcggc catgtacgcc agagtcagcg gcgtactcag cggaggaata
      901 tacgccgggc aggacagcca tttttacggc caccggaaaa ttttaaaacc cgatcacctt
      961 aactgggagg agtacgcgct gctcctgcta cacagtatgc ctgaagtcac tgccgaacat
     1021 taccgtaata aaatcgccgt ttatttgcag tggtataaga aaaaaggcat gaacaccatt
     1081 ccacagacgc agcagggcga tatcggatcg cgggatattc cgtcatggcg acggatctgc
     1141 aaagtattac tgaacaatga ttactggtgc cgggcgctgt cattcagtcc gacaaaacct
     1201 aagagttacc agcgttataa cgaacgcatg aaagctaaac gccaggaatg ggggatctta
     1261 tgcaacaccg actcacaacc gaaataactc actttctctc tggactgcct gaagaggaaa
     1321 ggatcgccgc cattaatgaa tttagaaggg cgatacataa cgttagtcct tttcgcgatg
     1381 agccagtcga ttgtgtcctg tgggtgaaaa acgatcatat ttcgcctaat gactacaacc
     1441 cgaataacgt tgcgccaccg gagaaaaaat tgctgcttaa atcgattgaa aaagatggct
     1501 ttactcagcc gattgtggtg gtaaaggcca atacggagga atacgagatt gtagacggct
     1561 ttcaccgtca tgagttgggc aaaggaaaag cggtcctgaa aaggcgcctg aaaggttatc
     1621 tgccggtagc gtgtctggac agagaacgtc acgaacggat ggcggcaacc atccggcata
     1681 accgcgcgcg cggacgccac cagatccacg ccatgtccga aatcgtacgc gaactttctc
     1741 agctaggctg ggacgagagc aaaatcggac aggagttagg tatggacgcc gatgaagtcc
     1801 tgcgcctgaa acagatcaac ggactgcagg aactctttgc agaccgtcga ttctccagag
     1861 cgtggacggt taaataacta cagtttacac aggcgctctg cggcggccag cagcgttgat
     1921 tcctgtttag cgaaacataa acgtataagc tgatgcggga aaggggcggc gcaaaagaca
     1981 gagagcggaa tagcggcgac accgacttct tcggttagcc actgacaaaa ctcaacgtca
     2041 tttagcgtcg acactgcgct gtaatcgatt aacaaaaaat aggtaccttc acagggcagc
     2101 acttttaatc ggctttgcgc cagcgcgtta accagcacat cgcgtttttt ccggtaaaaa
     2161 tcgggtaacg cgcgatagtg ttccggcgcg gcgcgcagca tatccgccag cgccagttgc
     2221 gccggcgtat tgacgcaaaa cgtcaggtac tggtgaactt tgcgtatttc ggcgctaatg
     2281 gccgcaggcg caacgcagta accaatcttc catcccgtca tatgaaaggt tttaccaaac
     2341 gatgaaacgg caaccgcccg ctctcgtaac tgagggtgcg ccagtacgct ggcatgacct
     2401 tcggcggcaa aacaaatatg ctcgtacact tcatcgctta atacataaat ttcccgctcg
     2461 ccgatagcct gccacagcgc ctcgatatcc gcctgacgcc agacggtagc ggtgggatta
     2521 tgcggcgtat tgaggatcac cagccgcgtg cgctcgctaa gcaacgccga aaacgcctgc
     2581 cagtcgacgc gaaaatgcgg cggcgtaagc gctatgcgtt ttaacacgcc gccggaaagc
     2641 gccacggccg gggcatagct gtcgtaactg ggatcgaaac agataacctc atcccctgcc
     2701 cgcaccagcg cggtaatcgc cgcatacagc gcttctgtcg cgcccgccgt gacggtgata
     2761 tcacttacgt catcgggtcg ataaccatat atttccgccg ttttatcggc tatggcctcc
     2821 cgcagcgcct gcgcgcccgt catcggcgca tattgattcg cgccctgcgc gacatgataa
     2881 gccaaccgct cgtgcaaata agaaggacca tcaaaatcag ggaagccttg cgataaattt
     2941 attgcctgat gtttctgcgc cagcgcgctc atttgcgtaa aaatcgtggt gccaagattg
     3001 ggcaatttgc tctttggaat cagtgggtta tttctcatta tcttcatacc cgccagtgat
     3061 gtggttgttg acacactatc acagggtgtt agtatttggc aatcaagacg tttagatgtc
     3121 taaatataat aacagcggtg agaagaccct aaggacaaca caacatgaac cacactgaga
     3181 tccgcgtcgt taccggcccg gcgaattatt tttcccatgc aggaagcctc gaaagactga
     3241 ccgacttttt cacgccggaa cagctttccc acgctgtttg ggtgtacggc gaacgcgcga
     3301 ttgccgccgc ccggccttac ctgccggaag cgtttgaacg tgctggcgca aaacatctgc
     3361 agtttaccgg ccattgtagc gaacgccatg ttgcccaact ggcgcacgcc tgcaacgacg
     3421 atcgtcaggt ggtaataggc gtcggcggcg gcgcgctgct cgataccgcc aaagcgcacg
     3481 cccgccgtct ggcgctgccg tttgtcgcta tcccgacgat cgcggcgacc tgcgccgcct
     3541 ggacaccgct ttccgtctgg tataacgacg cgggacaggc gttacagttc gaaatttttg
     3601 atgatgccaa ttttctggtg ctggtcgaac cgcgcattat tctgcaggcg cccgatgact
     3661 atctgttagc tggcattggc gatacgctgg cgaaatggta tgaagccgtt gtgcttgcgc
     3721 cgcagcctga aacgttgcca ttgaccgtaa ggctgggcat taacagcgcg tgcgctattc
     3781 gcgatctcct actgaccagc agcgaacaag cattagcgga taaacagcag cgtcggctga
     3841 cccaggcatt ttgcgacgtg gtggatgcga ttattgctgg cggcggtatg gtcggcggcc
     3901 tcggggaacg ctatacccgt gtcgccgccg cccatgcggt acacaacggt ctgaccgtcc
     3961 tgccgcaaac ggaaaaattc ctgcacggaa cgaaagtggc ttatggcatt ctggtgcaaa
     4021 gcgcgctact gggacaagat gacgtgctgg cgcaattgat tacagcgtac cggcgatttc
     4081 atctgccgac ccggcttagc gaactggacg tggatattca taacaccgca gagatcgata
     4141 gggtcatcgc gcataccctg cgcccggtcg aatctatcca ctatttaccg gtgacgttaa
     4201 cgccagacac cctgcgtgcg gcgtttgaaa aagttgaatt tttcagaata tagcctggtg
     4261 gcgttgcgct tgtcagacct ggcaaccatc agcagcaacg cgcgccgcct tttccaccat
     4321 agcgcgcatc ctgccgctcg cggaaaaatt cttcataggt catcggcgtc tgatccggat
     4381 gcgttatgcg catatgttcc acatagttgt cgtagtctgg cacgccaatc atcatttttg
     4441 ctgcctgtcc cagatatttt ccggctttcg aaagcgtatc gaacatcgtt gtcacctgtc
     4501 atccaaacgc cctctcctta ttctggagag ggctattgat gaaaaaagat tagtgcgcgc
     4561 ctttcgcttg cgtcacgatc tcatccacat tttccggcat cggctcatac ggcgtttcat
     4621 tcgccgtcgg tttatcaatc ttcagagcgg ccagcgccgt cttaatagag aagaccgcca
     4681 gcaccacgac caccaccata aagaagatgg ttagcccggc atccagacgg ttattgaata
     4741 ccaactgcgc gagctgcgat tcggtgtact gcggcggaat attgccgctg tcgatcatcg
     4801 cctggaattt attggcaatg gccaggaagc cgattttcgc atccggacta aacgctttct
     4861 gccagcccgc cgtcagcgta caaatcagca gccaggccgt cggcaccagc gcgacccacg
     4921 cataacgctg acgcttcatt ttgaaaagta ccacggcgca aagcatcagc gccatccccg
     4981 ccagcatctg gttggcgatg ccaaacagcg gccacagggt gttaataccg cccaacggat
     5041 cgaccacgcc ctgatggagg aaataccccc acgccagcac gcacaatgcc gtagcaagca
     5101 ggttcgctgg cagcgaatcg gtacgtttca gccctggcga cactacgccc aacaaatcct
     5161 gcaacataaa gcgcgccgca cgggtacccg catccaccgc cgtcagaata aacagcgctt
     5221 caaacagaat ggcgaagtga taccagaacg ccacatccat catgccgccc aacgcgccat
     5281 gtaaaatgta ggccatccct accgccagcg ttggcgcacc acctgcgcgg gagataatgg
     5341 attgttcgcc gacttcattg gcaatctggt gtaacgtatc cggcgtgata gcgaaccccc
     5401 aactactgac cacctgcgcg gcagaagcta cgacatccgc tgtccccgct ggcgccagta
     5461 ccgccatcgg gctattcatc gcaaagtaaa cgcccggatc gataatacag gcggagacca
     5521 gcgccataat ggcgacgaaa gattccatta acatcccgcc gtagccgata aagcaggcct
     5581 ggccttcgtt ggccaacatc ttcggcgtcg tgccggagga gatgagcgca tggaaaccgg
     5641 ataccgcgcc gcaggcgatg gtaataaaca ggaacgggaa caggtcgccc gtccagacgg
     5701 gtccggtacc atcaacaaat ttggtcagcg ccggcatggt cagcgtcgga cgcataatca
     5761 gaatcccgac tgccagaccg acaatcgtac caattttcag gaaggtagag aggtaatcac
     5821 gcggcgcgag cagcagccag accggcagta ccgccgcgac aaaaccataa cccaccagca
     5881 tccaggtaag ctgcacgcca gtaaaatcaa agtacggcgc ccaggttggg cttgccgcca
     5941 cccatccccc ggaaataata gcgaaaataa gaaataccag cccaatgacc gacacctcgc
     6001 cgatgcgccc cggacgcaga taacgcagat agatgcccat aaaaatcgcc agtggaatag
     6061 tgaacgcgac agtgtacgtt ccccacgggc tatgggtcag cgctttcacc acgatcatcg
     6121 ccaggacggc cagaatgatc accatgatca taaagcaggc taccagcacg atcacccctg
     6181 ccgtcgcgcc catctcctct ttaaccagct cgccaagcga acgcccatcg cgccgggtcg
     6241 agacgaacag caccataaag tcctgcaccg ctcccgccag cacgacgccc gccagcagcc
     6301 agatcatccc cggcagatag cccatctgcg ccgccagtac cggcccgacc agcggacctg
     6361 cgccagcaat ggccgcaaaa tggtgaccga acagcacttt tttatcggtc gggacataat
     6421 ccagaccatc attatgacgt accgcgggcg tcatacgcgt tgggtcaacc gccagcactt
     6481 ttttggcgat atagagccca taaaaacgat acgcaataag atagacacag accgacgcca
     6541 ccacgatcca tagcgcgttg atctgttccc cacgatttaa cgcaatatag cctagggcaa
     6601 acgcacccaa tactgagagc gctgtccaga cgaggtattt ccctgattta ttcatagttg
     6661 ttgtccgttt gggtgttcca gagagatgtt acattttgtt tctatgacac ctttaccgta
     6721 attaacaaca caacaacatg ataaaaccgg attgttaccc attttttaca ttacagtgtt
     6781 aaccagatca cttcctttct tcgttaatgc tgcaattgca ttttactttg ccagaactat
     6841 cccattaccg ccgttcccag gcgacaagtg cagcagcgcc tcccctgctc gtcaaagagc
     6901 gtaatttccc agctttgatt ctgccgcccc agatgcagcg gcaggcaaac gccgcgtact
     6961 ttcccctgcg agacggcgcg gtgatgggtg gcgtttaact cggtcccgac cacgcactgc
     7021 ccgtcgcggg tcatcagata acccgccatt gatcctaacg tctccgccag cgctgccgat
     7081 gcgccgccat gtagcagacc aaacggttga tgagtgcggg catcgacggg catttccgcc
     7141 tccagcacgt catcgcccag acgggtgtaa acaatgccca gatgcgccac cagcgtgttc
     7201 tgactggtag cattcaattc atccagcgtt aaatgccgtt tccagatcat cgtcaggctc
     7261 ccaatgttga accgccgtcc accacgatat cctgcaaggt aatgtggctg gccagatcgg
     7321 aggcaagaaa caaaatggta ttggctatct cctgcggacg ggcgatttta ccgagcggta
     7381 tgccgagctt aaactgttcg ccgaaaccgc gaatgcgctg ctgttcggca tcttcactca
     7441 cccataacgt gcgctgcata tcggtgtcgg tcgagcccgg cgacaccaca ttacagcgta
     7501 ccccgcagcc cgccagctcc agccctacgg ttagcgccag gcttttcagc gccgctttag
     7561 aggcgccgta agcgcccata ccgatacgcg gcgtatgcgc cgcatctgag gctacggtga
     7621 caatcgcccc tccctgctga cggcgaaact gcgccatcgt ctgggaaaac aggttaaatg
     7681 ccccgcccac attgaccgca aatgtctgct gccagtcgtc gacgttaagc gcgtcggtcg
     7741 ctcccatacg caaaataccg gcggcgttga ccagcacatc cagccgcggc gttttttgca
     7801 acacacgctg gcacacctgc gcaacctgtg cggcatccgc cacatccata acttcggtag
     7861 caaagggata attctcttgc gtaaattcgc gatcgaagcc gatcacccgc gccccggcgt
     7921 cgacaaacgc cagcgccgtc gcgtaaccga tccctttccc cgccccggtc acccataccg
     7981 ttttgtctga aaaatcaaag ctggccatta ctctaccccg cgagaaagca gcgcccacca
     8041 ggcgtcaatg gtcggatttt tcgccagcat cacgaagtcg atatcgccgt gtactttacg
     8101 ccagcgcgcc gccagcccca tcatgcgtac tgaatccagg ccataatcaa tcaggttttc
     8161 atcatccagc ggctcgtcgg tctcatccag taacggcaga atcaacgccc gcagcgccgc
     8221 tttactggca ggaatcggcg tcggcagcag cgactctgtc atgacgacgc gaccggaacg
     8281 ccccgccaca tagttcagcg ccatcagatg ctcttcccga ctgaaatccg ccagcgcatc
     8341 cgccaccata aacggcttaa tgtcgcgcat aaacgcatcg gtagcggtgg tcatacagcc
     8401 aatatgtgca tatacgccgg taatgatgag ctgattgcgt ccggtatctt ttaacatctg
     8461 ttccagcggc gagcggtgaa acgcgctata acgccacttc accagcaccg tatccgcctc
     8521 atccggcgtt aaggcttcta ccaccttctg ctgttccgga gagcgcgtca gtcccggtcc
     8581 ccacatatca ttgagtaacg cgcgatcttc atcgctttgc tctttcggct gagcggtgta
     8641 ataaaccggg atatgatgtt ccttacagta ctggcgcaga gcggcgatat tggcaattac
     8701 ctggtccatc attgggcaat tgcggcccca aaagctgaca aagtaatcct gcatatcgtg
     8761 gatgagcagc gccgcgcgct ccggctcaaa tgcccagttc actttgttgg tcgggatatc
     8821 cagtgcggtg ggcagcgcgt aagactgtag tttcgggatt gccatctctc tttctccttc
     8881 agagcggtga acgtgacgcc aaccgctggc gtaattgttt tttatcgact ttaccaaccg
     8941 gcgtcagcgg cagtgacgca acgcactcca cgcgatccgg taatttaaat tccgccacgc
     9001 cctgctctcg caggaaacgg cgtacctgta ccgctcgcag cggctctttt accaccagat
     9061 atgcgcaact tttttccccc agcagttcat cttccatgct gaccagcgcc gcatggatca
     9121 ccgccgggtg gcgcagtaac aggttttcta tctcttcggc ggctatcttc tcgccgcccc
     9181 ggttgatctg atctttttca cgcccgtgaa cggtgatgta gccgtcttga tcaatggaga
     9241 tcagatcgcc ggaacagtaa aaaccgttgg cgtcaaaggc gctgacattg tgttgcggac
     9301 tgttgaaata gccgcgaaaa gtataggggc cgcgcgtcat cagacgacca atctcgcccg
     9361 gcggcagtgg attcccgtcg gcatccgcca cccacacttc gtcgtccgga cacatgggtc
     9421 ttccctgggt attgataatc cgttccgggc tatcgtccag ccgggtatag ttcactaacc
     9481 cttccgccat gccgaagacc tgctgcaact gacagccaat ttcagccgga atacgggcgg
     9541 ccagcgtcgc agaaagccgc gcgccgccaa cctgcaataa ccttaatgac gccagcggcg
     9601 cattgccgcc ccactcctgg atagcctgta gccatagact gaccgcgggc ggcaccagcg
     9661 ccgtggcatt aatctggtgt ttttcgatca gcgggaaaca gagcgtggcg ccaggatcgg
     9721 tcgccagcac taccgttcct ttggcgagaa aaacgcccag cgcgcccggc gaactcatgg
     9781 cgtagttatg cgcggcggga atcgcgcaca gaaaacgcgt ctcctcgttg aaaccgcaaa
     9841 tctcattgct gcggcgcacg ctgtagtaat agtcgttatg ggtacgggga ataagctttg
     9901 gcgtgccggt agtaccgccg gaaagctgaa agtaggccac ttcgtcagca ggtgatggcg
     9961 tggcggtgaa accttccgcc gcctgccgca tcgccgcgtc caggctgtga tcgccgtcgt
    10021 cgttgcgcaa taacaccacc cgcgcagagc ggtgttcagc cacaaacctg ttgagaaagt
    10081 cctccccggc gaacagcgta tgttggcgat cggcaatcac cagcgtcggc gcgatctgca
    10141 tcgcataggc gttaagttcg gtacgttgat ggctaaacag cgccagaacg ggcgctacgc
    10201 caagcttcaa cagggcgaaa aaggtgatat acagttccgg tacattcccc agttgtacca
    10261 gagcggtttc gccaggtttg atgccctgac ggcgtaaact gcaggccaga ttatccgcgg
    10321 cctggtttag ctggcgatag ctgaatgcgc gctcgccttc aatgaccgcc gtcttatcgc
    10381 tgtcagcgtg gcgggtcaga atatcggtca acggcacgtc ttgccagtag cctttttcac
    10441 gataacggcg ggcaaattca tccggccaac gggtgaaagg tatacgcatc atcgttcctt
    10501 aatgcagtcc aaaaacgttc aacatcgtag agagcttgac gccggtttcc cgccactcgc
    10561 cgactggcga agaggcagga acaatcccgg cgccggcgaa caggcgcacc tgattaccgt
    10621 gcaatttcgc acaacgaatc gtcactaccc actcgccgtt tccttcggca tcgcaccagc
    10681 cgacaatgcc gccaaacagt tcacgatcga acggctccag ttcagcaatc agctttttcg
    10741 cgacctgatg ggggaaaccg cttaacgcag gggtcggatg cagcagacag gccagcgtaa
    10801 gcgcgttttc tccggcgttg gccttgccct caaacggcgt accgagatgc catagcgtcg
    10861 gcgtggtgat caactgcgga gaggaaggta attgcagttc cgtgctgcga tcgcgcagga
    10921 tctgcttcat cgcctgcgtc accagctcat gttcatggcg atctttttgt gaagccagca
    10981 gtcggtctcc cgcctcgcga tccagaacgt catcgggctg tcggcgtgcc gagcctgcta
    11041 acggcagcga actaaaccgc tcgccctcct tgcgtagcag caattcgggg ctggcgccca
    11101 gcagaacgcc gccatccgcc agtggcacat ggaagttgta actaactgga ttctgcgcaa
    11161 ccagccgctc cagcaatgct ccgctatcca ccgccacatc agtggtgata tctatcagcc
    11221 gggaaagcac cactttatcg acgtctggcg tggcggtcag catagccgcg cgtgcgacca
    11281 tcgcttcaaa agcatcctgc tccggaatcg cctttcgcgc cgtcaccgtc agcggctgat
    11341 ggtcagtaaa ataacgcgcc gtgcgctgct tttgctggcg ggaaaaggac tgccacgcca
    11401 tcgggataaa tagcgacgac ggctgacggg tatcaaaggg gatcgccccc accaggacag
    11461 ggttggcgat gccctgcgat ttggcctcgg caaactgctg gcgcaatttc tgctggaaag
    11521 ggctatccgg cgaatctccg gcaaccgcag gctcggtata acgggcgaag cacccggaag
    11581 tggtaaaact gcgatacggc gacatgaaga aaaagcgatc gggagcaagc gttgccattg
    11641 tctcctgagc gtcctcggcc agtgacatat ccatatcatc ctccaatgat aaaggcttat
    11701 atacacttca tctttcaagc tgcctctttg ttggctgcga tcagaaaccc cggtcacaca
    11761 gttatctatg cccgcgggga ttcttccctt gccgtcgcga tgcttcttga atgattttgt
    11821 gtataataat gattattatt tctattttta gtgcgctaac ctaagagtaa aacgtcgctc
    11881 tgtcaactct ggtcatgagt taaatggcac taaggcttgc atctcgctgc cgctgacatg
    11941 aaaatgagaa gcattaactt tattaataac aggacgctat tgtgagactc tccgcctttt
    12001 atcgttggct gcttttagtg gttggtttat caatttcagg aatatcctta gcccaggacg
    12061 ccggttggcc ccggcaaatc caggacagcc gaggcgttca tactctggac cacaaacccg
    12121 cgcgtatcgt ctctaccagc gtgacgttaa caggctcgct gctggcgatt gatgcgcccg
    12181 tcgtcgccag cggagccact acgccgaata accgttttgc cgacgatcaa gggtttatgc
    12241 gccagtggag cgatgtagca aaggctcgcc atgtcgcccg gctgtacatc ggcgaaccga
    12301 atgccgaaac ggtcgccgcg caaatgccgg atctcatttt gattagcgcc accggcggcg
    12361 actccgcgct ggcgctttac gatcagctct ccgccatcgc gccgacactc gtcatcaatt
    12421 atgacgataa aagctggcag agtttgctca cgcagcttgg cgagatcacc ggtcaggaga
    12481 aacaggccgc cgcgcgaata gcggaatttg aggcgcaact gacgacggtt aaacagcgaa
    12541 tcgccctgcc gccgcagccg gttagcgcgc tggtgtatac tcctgccgcg catagcgcca
    12601 atctgtggac gccagaatca gcacaaggca agctattgac gcagttaggc tttacgctgg
    12661 cgacattgcc ccaagggctg caaaccagca aaagccaggg taagcgccac gatatcattc
    12721 agcttggcgg tgaaaatctg gccgccgggt taaacggcga atctcttttc ctgtttgccg
    12781 gcgacaacaa cgatgttgcg gccctttacg ccaatccgct gctggcgcac ctgccagcgg
    12841 tgcaaaataa gcgcgtctat gccctgggta cggagacgtt ccgtctggat tattacagcg
    12901 caacgttgct gcttaatcga ctggccgccc tgttttagcc ttatcggagt cttatccgac
    12961 tgaccagaca gatttggtca gtcggataaa cgcgtcttca tcagccagca tcgctaaccg
    13021 gcggcgtctg gcgaaaacgg cgtagctcgc ccagcactaa cagcagcagc aaaccgataa
    13081 tcaccagccc gaatccactc acgctcgcgg aagcgaccgg cgtcatcatt gcgccaagac
    13141 cgcctaacag cgccgcgccg atagcgtctc ccgtgacgtt ttgcgcggtc cacaggccgt
    13201 tcattcgccc cagcatattt tccggcgtct gggtttgcag cagagtgtat tgtaataacg
    13261 aactgatggc gctaagccag ccaaatagcg ccagacagat aacaccagcg atccagatcg
    13321 gcatgatggc gaacagcccc accgccagaa aagaaccgac tgtcgaaacc agcataatga
    13381 gccccggacg aacgctatgc gccagttgtc cgctggtcag cgcgccaatg gccgccccca
    13441 gcggaattgc cgcatacagc aaaccgattt gcgccgccga catctgccag ctcatcgcca
    13501 gcgccggata gaggacgcgt accgcgcttg ccatcgtcac caggccgcca agcagcgcaa
    13561 taccgccgat aagcggactg gcgagcaaaa aacgaaatgc cgccagtaac gcgataaatg
    13621 gattttcccg cggctgcgga ggaacaggca gtcgcggcag cgtcagtaac ggcaatagcg
    13681 taataaacgt cccggcggcc gccagcccat agttccaggc tacgccgccg ctggcaagca
    13741 atatgccccc caacatcggc gaaataaccg atcccagacg taccgtcagc atggtaatcg
    13801 cgccggcctg catcagattt tctcttccga ccagcgctgg cgtcgccgcc agtaacgcgg
    13861 tcacgcccag agacgcgaaa aagccgtccc acaggccaag gagatatatc gccagcaatg
    13921 acggttccgg cagcagcgcg ttcacgcaca gaccaataaa gccaataccg caagtaccgc
    13981 gcgccagcag aatcaccttt ttgcgttcgt agcgatcggc cagtacgccg cccaccatta
    14041 agccaataaa catggcgccg ccggttaacg ttaccgacag ccctacctgc caggtagagt
    14101 gcgtcatcat ttggatctgt accggaaccg ccacgccaag cagccccagc gagacaatag
    14161 agataaaacg ggccagaaat actgcgcgaa atgcagggtg cgtcttcaac aggctgagat
    14221 tgagcagcca ggattgtcga ttcattacaa cgccttaatg cgagtttttt taaatatcca
    14281 ttcaatggct gcacatgcta atataaccaa ataagataga taacgataat tactatcatt
    14341 atcagggaag ttactatgtc atgctcgttt tccgtgacgc gcgcgtttgc cgtgcccgga
    14401 ttgttgttat tactgagtct cgccgcggtt ttaagcctgg tcattggcgc gaaaccgctg
    14461 cccgccgccg tcgtgctgga ggcgttcacc ggcgtgtgcc aaagcgccga ttgcaccatc
    14521 gtcctggatg cgcgtttgcc gcgtacgctg gccggattac tggcaggcgg cgcattgggt
    14581 ctcgccgggg cgctcatgca aacactcact cgtaacccgc tcgccgaccc ggggattctg
    14641 ggcgttaaca acggcgccag cttcgccatt gtactgggcg cggcgctgtt tggtttctcc
    14701 acgccgctgg aacagctttt catggcattt agcggcgcgc ttatcgcatc gctgattgtc
    14761 gccttcaccg gtagtcaggg cggcggccaa ttaagcccgg tccgcctgac actggcgggc
    14821 gtggcgcttg gcgcggtact ggaaggacta accagcggca tcgcgttgtt aaatccagag
    14881 gtctatgacc agcttcgctt ctggcaggcg ggatcgctgg acattcgtag cctgcaaacg
    14941 ttgaaagtcg cgctcgcgcc cgtggttatc gctgggatcg tggcgctatt tctgagccga
    15001 gcgctgaaca gcctgagcct cggcagcgat accgcgacgg cgctggggag taaagtggcg
    15061 cgcacccaac ttattggttt actggcgatt accgtcttgt gcggcagcgc aacggcgctg
    15121 gtcggcccta tcgcctttat tggtctgatg atgccgcata tggcgcgttg gctggtgggc
    15181 gcagaccacc gttggtcgct gccggtaaca ctactggcaa cccctgctct gctgcttttt
    15241 gccgatatta ttggtcgtct gttagtgccg ggcgaactcc gcgtatcggt cgtcagtgcg
    15301 tttatcggcg cgccggtact tatctttctg gtacgccgta aatcgagcgg aggcggcctg
    15361 tgatgtttct ttctcgtcgg cttatcgtaa gctgcctgct tctggcggct ggctgcttcg
    15421 ccattggctt atggagcctg caaagcggcg ccgtgcccct tgagaccggg cagattattg
    15481 ccgcgctgct gggcgacgcg ccgcgtaata tcacccttgt cgtaaccgaa tggcgactac
    15541 cgcgcgtatt aatggcgcta ctgattggcg ctgcgcttgg cgtcagtggc gcgatttttc
    15601 agtcgttgat gcgtaacccg ctaggcagcc ctgatgtgat gggctttaat accggcgcct
    15661 ggagcggcgt actggtcgca atggtcctgt ttggccagca tcttaccgcg atcgcgctgg
    15721 cggcaatggc gggcggtatc gtcacgtcat tgattgtctg gctgctcgcc tggcgtaacg
    15781 ggattgaaac tttccggctg attatcatcg gtatcggcat ccgcgcgatg ttagtcgcct
    15841 ttaatacctg gcttctgttg caggcgtcgc tggaaacggc gctcaccgcc ggcttatgga
    15901 acgccgggtc gctcaacggt ctgacatggg caaaaacctg gccttcggcg ccgctgatta
    15961 tggtgatgct gacaggcgcc gcgctactgg tgcgtcgtat gcggctgctg gagatgggcg
    16021 atgacagcgc ctgcgcgctg ggtgttagcg tggagcggtc acgcctgatg ctgatgctgg
    16081 tggcggtgtc gctcaccgct gctgcaacgg cactggctgg ccccatctcg tttattgccc
    16141 ttgtcgcgcc gcacatcgcc cgtcgtctta gcggcacagc gcgctgggga ttaacccagt
    16201 cggcgctgtg cggcgcgtta ttactactgg ccgccgatgc gtgcgcgcag caactgttta
    16261 tgccttatca gcttccagtg ggcgtggtca ccgtcagcct cggcggtatt taccttatcg
    16321 tcttgttaat tcaggagtcc cgcaaaaaat gaccgaatcc gtagcccgtt tgcgcggcga
    16381 ccagttaacg ctgggttatg gcagctatac cgtcgcaaaa aaccttaatg tttcgattcc
    16441 ggacggccat tttaccgcca tcatcggccc taacggctgc ggcaagtcga cgttgctacg
    16501 tacgctaagc cgtctgatga cgcctgttga cggccatgtc tggctggatg gcgaacaaat
    16561 acagcgttac gccagtaaag aggtggcgcg gcgcatcgga ttgctggcgc aaaacgccac
    16621 cacgccgggc gatatcaccg tacaagaact ggtcgccaga gggcgttatc cgcatcagcc
    16681 gttatttacc cgctggcgca aggaagatgc cgacgccgtc gccagtgcta tgcgtgcaac
    16741 aggtatcacc tcactggcgg cgcaaagcgt agacacgctg tccggcggcc aacgtcagcg
    16801 ggcgtggata gccatggtgc tggcgcagga aacgtccatc atgctgctgg atgagccgac
    16861 aacgtggctg gatattagcc atcaaattga tttgttggaa ttgttaagcg atctcaaccg
    16921 tgaaaaaggc tatacgctag ccgccgtcct gcacgacctg aatcaggcct gccgatacgc
    16981 cacacatttg attgcattac gcgaaggtaa cattgtcgca cagggcgcgc cgaaagagat
    17041 tgttaccgct gagcttatcg aaaaaatcta tgggctgcgc tgtatgatta tcgacgatcc
    17101 ggttgccggg acgccgctgg tggtaccgct ggggcggcga tagtcgccca cacagatgac
    17161 aaagccggat atcgctatcc ggcttttcgg gtaaatcaga ctaaccgttc atctatcgcc
    17221 agcgcgtttt ccattttacg cgagaccatc gcgtgacgca gtaatacgcc gccgcaggcc
    17281 atcataccgc caatcaacgc cgccaggata ataatgatcg ctttacccgg gccatctttt
    17341 ttcactggca gagacggcga cagttgatat ttaaacgggg taaacttcac gtcgctcaca
    17401 ttcattgccg ccagttgttc aacatagtat tgacggttac gcaaatcacc gtcgatctcg
    17461 gccacgtccg ttaccccttt ttcaatttcc agtttgcggg aaataccatc cgcgccgagg
    17521 gaaatagaaa aatccggatc atcttttacc gcctgaccat tactgtaaac cggtctctta
    17581 atgccagcgg cgttggcgat ttccagcgaa taatgaagac gttgaatatt ggcatcaagc
    17641 tgatttttga gacgcacccg atccatcgcc agcttttcct gctcgtagcg ggttttgatt
    17701 tccagctggt tacgaatatt ttccagcgtc tctttcacga cgatatcgga gatgtactga
    17761 atatagccag ccaacacttt ttgcgcttct tcccgcgtcg gcgcggtaaa actcagcgtc
    17821 cacgacgtga ataacgacgt ttcatttttc ttgccggcat tgctgtccac cgctttcatt
    17881 ttttcgctca gcacgacaat cgcccggtga agatcctgct cgtctatttg cgcgcctttt
    17941 aattgatcca tgacatacgg agaagaacga agatattctt ccagcagcga gggcgagcta
    18001 aactttttaa taaacagatt aaatacgctg gcccgatcaa cgcttacctc catatccaac
    18061 acgcgcagcg cggtcaacgt tctctccagc ccctgctact gtaccgactc cgccggtgtg
    18121 acaatcgcct ggctggtcca tttttgcggc agcagaaagg acagaagcaa ccccacgcac
    18181 gcaaaggcga aaacggtagc aagaatacga cgtttcgcct gccataacac ctctataagg
    18241 ctaaacaaat cgatttcatg actgttggcg ggcggcagtg agtaacctgc aaatgactga
    18301 tttttctctt gttttacatt aagagatggc atgccgtatg acctgaaaac tttatccaat
    18361 gaaagaacac attcctgtca gagattctaa cagcaagtca gaattatccg aaacaatctt
    18421 tacgcgccag tgcccgaaaa gctaaatatt cggaattaaa cttgcctgta gcatgtatca
    18481 cttatgttaa aagaattaat agttgcaata aaaaacccat aataattagt cattattatg
    18541 ggtttcagga tttaatttgt taaaggcaga aacaacgccc gttatttatt aataagttcg
    18601 ctgatgatgg gcccgatagt ttcaaaagcg gagggagaaa taatatctac atgcgcgcac
    18661 ggctggcgat aaatagccaa agacgctatc cacggcgacc agctctgttc aggcgatacg
    18721 tcttccggca ccgttttatc cgccacaaag agcgtggcat gtccatcaaa cggtgcgcta
    18781 tgcgccgtcg tcagcaaacg gacggcatcc gcataattgc cttcaatggc ggtaaataag
    18841 gcgtcggagg catttccctg ctgcgcggcg acaaacgctg cgcgttcgcg ttcaatttcc
    18901 gccaatacgt ccggattgag gccattcgcc tcttttcccc gccagttttg tgtttccggc
    18961 ggccaggtgt ccagtaaccc caaaaacgcc accgtttcac cgcgcgcgcg caaccgggcg
    19021 gcgatccctt gcgccagcgt cccgcccagc gaatagccta ataaataata agggccatgc
    19081 ggctgccggg cgagcaatgt cgccagatga tgttcacata cctcatcaag ggtggttgcg
    19141 atttgcatag ggccaacggg gcgcggcgac tgaatcccca taatcgacca cgacgggctg
    19201 agatagcgtg ataatacgct aaattgccag gcgaaccccg acgccggatg gaaacaaaat
    19261 aacgttggac catcgctttc acgcagcggc aacagcggcc cgaaccccag attgcgcgag
    19321 cgttcgtcat cgtcagtatc gagcagctta ctcaactgcg ccacgtcaga cgccaccatc
    19381 acctgccccg gcgtcacctg gcggttaaac gtctggctta gctgcgcggc cagtttcatc
    19441 gccagcagcg agtgtccgcc cagcgcaaag aaatcacttt caacgtcgtt aatctcacag
    19501 cccagcaggc gggaaaacgc cgcggcgaca gcaatctccg ttgcggactg cggcgcacgc
    19561 cctttcacgc gcggcgtcag atccggcagc ggcagggctt tgcgatccag cttgccatta
    19621 gcgctaagcg gcaagctggc aagttgcaac agcacaaccg gcaccatatg cgcgggaagt
    19681 ttttggcgta atttatcctg cagcgccggt aaatccagcg gtaaaccgga gtgcgacacc
    19741 agatagccga ccagttgccg ggcatccccg cccgtcgccg ccgcctgatt aaagacgcag
    19801 gcatgtgcta ccgcctgttc aacatccggc agcgtttgca tgacgcggtc aatctcaccc
    19861 agttcaatac gttgcccccg aattttgagc tgatcgtcgc tgcgtcccag gtactccacc
    19921 acgccggaat ccagccagcg cgccacatct ccggtacggt acatccgttc acctggcgca
    19981 aaaggatcgg cgataaaacg gctggcggta agatccggac gccccagata gccctgcgcc
    20041 agttggatac cggtaagata gagatcgcca gccacgcccg gcggcaccgg ctgcatatgc
    20101 gcatcgagaa tacgtaaacc ggtattccag acgggataac caatcgggat actgttgccg
    20161 tcaacagccg ccagctcatc gccacaggcc ggataccagc tcacatccac cgcggcctcc
    20221 gttggcccgt acagattgtg tagcggcgcg ttggttaacg tctcccattc gcggcacagc
    20281 gccgtcggca gggcctcgcc gctacagaaa acgcgcttta aggaagcgca gcttttccca
    20341 gccgacgctg gcgtgagcga ggcaataaag gccgccagca tcgacggcac aaaatgggtg
    20401 gtcgtgacgc cgtattgcgc aaagaaccgc tgcatcgcga gcggatcgcg gtgcgcttcc
    20461 ggttcagcca tcaccagttt cgccccggcg ataaacggcc agaaaaactc ccatactgag
    20521 acgtcaaaac tgcacggtgt tttttgcgct actacatcat ccgccgtcaa cggatagtga
    20581 tcctgcatcc acagcagccg gttgactatc gccgtttgtc ccaccatcac ccctttcggc
    20641 ctgcccgtcg aaccagaggt gaaaatgatg taagcggtat gatgcggtag cgacagcccc
    20701 agcggagtgg cgtcactgac cggtagcggt tggctataac acaaatattc catccccgga
    20761 atatcgtgaa agcgcgccag ctgcgcctga gtcgtaatta acagtttcgg ctgcgcatct
    20821 tccagcatca ttcgcagccg atcgtcagga taaccggtat ccagcggcag ccaggcggcg
    20881 cccgcttcga caatgccgtg cagcgctaag gtcagaaaaa ccgaccgcgg caacgccacc
    20941 gccacgctat cgccaggctg aacgccgcgt tcccgcagcg cgtatgccag cgccacaacc
    21001 tgttcgcgca tttcacggta ggtaaagtga taatgcgcat ctgccaacgc ggaagcctct
    21061 ggcgtttttt gcgcctgctg cgccaccaaa tcgctaagcg tggcggcggg aatcgttacc
    21121 gccgtattat taaggtgtgt taattgcgtt tgttcttccg ccagcagcat ttgcgcatcg
    21181 ccgcagcgca gcgccgggtt atcagcaaac tgcgtgataa gcgccatcaa ccgtaaggca
    21241 tggcgggaaa gcgtggcgtc atcgtaacgc tgcgcattcg ccagcaattc aatatccaga
    21301 ccgccgtttt catccggaaa aagcgccagt tcaagatcgt taaccggccc cgtcgccagg
    21361 gtatgggttt gcgcctgtat gccaggaaaa tccagatgat aatcaaatac ttttatgttg
    21421 agcaccgggc caaatagcgg cgtttcccct gcggctcgcc cgctatcgcg tacaatctgt
    21481 tcggcgtcgt aacgctggtg gcggcgcatc ttctttaact gcgccgcaag acgcttcgcc
    21541 agcgttggca gatcttccgt cgcatgaagg ttaaccgcca gcggcaacac gttaaggaca
    21601 ggcccggtcg ccgttaacgc cgctgagccc atccgccgca taaagataaa tccggcggca
    21661 taatccatac gcccacataa tcgtcccagc cacaacgtca ccagcgccag ggcaagatcc
    21721 gctcgcggta tctcaggcat gtgcgccgcc agttggcgaa acgcccccgc cggcgcgctc
    21781 aatttcatac gcagaatatc cgcgctcgcc gaccgccccg gcaacggcgc ggcagacatt
    21841 gacgccggcg gcggcagctc gcggcgctgc tgcgcccaga aggcgccgtc acgctgccag
    21901 gcctcgctct ggcgatagcg ctgatattcc tcaaccacat ccacaaaggg ggtaaaaggc
    21961 gactccggcg taggggcgtc gctctgccag gcgcgataaa tcgccgcaat ctggcgagtt
    22021 atcgccggga agctaaagcc atccaccagc aaatggtgat agcgctgata ccaataccag
    22081 cgggtatcat caatgcggat taactggtga aacgccagcg gcttaccgct atctgcgcgc
    22141 aggttttgcc gtaaatccgc ctgcattaac gccagcgccg cgagatgcgg atcgggctgg
    22201 tcgcgtaaat cggcaatcgg gggttcgccg aaggtgtgct caggatctat ccattgccag
    22261 acctcgccgt tctcttcggt aaaacgcatc cgtagcgtat ccgcctgttg catccctacc
    22321 gctaccgctt ttgccagcaa gggggcatcc agctcgccat tcagttccac atagtgcgcc
    22381 acgctccagg cggagggtaa atcagagagt ttttccgcca tccagatccc cggctgggcg
    22441 gcgactaacg gtaaacgctg cgtcatttcg cctcctgctt atcggcataa tgcgccggat
    22501 tcagtgttgt ccagcgcgta ttaagccact gctggcacgc gtcctgcgat tgcggttcgc
    22561 ataccacgcc ccatcctgcg ggaagcgcgc acgccgctgg ccaaaggctg aattgacgct
    22621 gcgcattttg caggatgtaa aactgtccct gcggattatc gaagggatta ctgaattcca
    22681 tactcaactc ctgtcatgga catgtgcccg gttaaagcgt gtcgataagc ggctgccaaa
    22741 gcagcatcag cccttgcgtt agcccgccgc gccagcaaag cgcatcgtgt ccgccgtcaa
    22801 cctgacgcca gaaaatggac tgctgcgagg tattcagttg ggcataaagc gcctgatttg
    22861 cctgaaacac gatcggctca cgcacgccgg cttccagtac gatacgcagt ccgcgcgcgc
    22921 acaatgcgcc ggttttcagc cgggtaatga cttccccctc cggcggggtg atgcgatggg
    22981 gccaccagaa cgatcctgac tggcttagta cacagccaaa acgcgtcggc cagttcaggc
    23041 cggcatacag cgccgacagg ccaccaaagc tctgtccggc gaccaccgtt cgtccggcat
    23101 catcgctaaa aggcgtcacg gctctgactt gcggcaacag ttcctgctgc accgccagcc
    23161 agaagtcggc attgcagggc aactcctggt tgcggtgttg agtatcaatc gcgtcaatca
    23221 gcagatagac ggcaccggga agcaggcgtt gatgagtcag cgaggcgagc gcgggccaga
    23281 cgggcatatt ttccgcccag aattgaccgt ccagcagaat agccaacggt ctttcctccg
    23341 tcgcctcgtc tccggtcgtc aatatccata cgcggcggga gttacccaga cgttcgctat
    23401 gccactgcat catcaaaggc ggtgagtacg acgtttcagg acgatcccat cccggctgac
    23461 ggggcgcatc cggcatttcc agcgctgaaa ccgcatgacc acgtcctccc cgccagcttt
    23521 gcgaattaag cgggtcggca atcgcctgcg gtaatagctg tcgccagcct tcacgcagcg
    23581 cgttccgatc gggcgtttcg cccggcgcaa aagcggcaaa aacgtcatct cgctcggtag
    23641 gaataaaaca gtagctgccg cgccagttag cgctaagcgc cgtgctccag cgccagacat
    23701 ccgttccggc aatacgcgcc atcgtctgag gctgcgcgtt ttgatgatga tcggttacgc
    23761 cagtgatgta gacccagaca cgccgtatcg gggagtgtgt ttcgtttccc tgcgggtcgc
    23821 gccaccaaaa agtgacccga taatttccgt ctttttcccg tatccattcc ggcccggttt
    23881 tcgtcctcca ccaggcctca cttcccgttg ccagcgcctc tttcattata accctgtgtt
    23941 tattatgaat tttgtatata aaaggtgaaa tatattgata atattattga taactatttg
    24001 catttgcaat agcgtattgt agcgctatgg gacgcgcgaa cacaatttca ccacccggcc
    24061 aatgcctttg acgggcgctt tggcttatgt ggctaaagaa aagcaggata tacaatgaac
    24121 aagaagattc attccctgac cttactggtc aatttaggga tttacggggc cgctctgccc
    24181 gtgatggcgg aagaaaaaac cgatagcgct gcgctcacca atgaagacac catcgtggtg
    24241 accgctgccc agcaaaacct acaggcgcca ggcgtatcca ccatcaccgc cgatgagatc
    24301 cgcaaaaatc cgcccgcgcg cgacgtgtca gaaatcatcc gcaccatgcc gggcgtaaac
    24361 ctgaccggca actccaccag cggtcagcgc gggaataacc gccaaatcga tattcgcggc
    24421 atggggccgg aaaacaccct tatcctgata gacggtaaac ccgttaccag ccgtaactcg
    24481 gtacgcctgg gctggcgcgg cgaacgcgat acccgcggcg ataccgcgtg ggtgccgcca
    24541 gagatgatcg aacgcattga agtgctgcgt ggccctgccg ccgcacgtta cggtaacggc
    24601 gcggcgggtg gcgtggtcaa tatcattacc aaaaaaggcg gtagcgagtg gcacggttcc
    24661 tggaatacct atttcaacgc gccggaacat aaagacgaag gcgcgaccaa acgcactaac
    24721 tttagcctga acggcccgct gggcggggat ttcagcttcc gtctgtatgg caacctcgac
    24781 aaaacgcagg cggatgcgcg taatattaac caggggcatc agtctgaacg taccgggagt
    24841 tacgccgaca cgttaccagc cggacgcgag ggggtcatta acaaagatat caacggcgtg
    24901 gttcgttggg attttgctcc gcttcagtct ctggagctgg aggccggtta cagtcgccag
    24961 ggcaacctct atgccggcga tactcagaac accaatacga accaactggt gaaagataat
    25021 tacggaaaag agacgaaccg cctctatcgg cagaactact ctctgacctg gaacggcggc
    25081 tgggataatg gcgtaaccac cagtaactgg gtgcaatacg aacatacccg taactcccgg
    25141 atgccggaag gcctggcagg cggcaccgaa gggattttcg atcccaaagc atcgcaaaaa
    25201 tatgccgatg ccgatttgaa tgacgtcacc ctacacagcg aagtgagcct tcctttcgat
    25261 ctgctggtca atcaaaacct gacgctgggt accgaatggg cccaacagcg tatgaaagac
    25321 cagctctcca actcgcaaac ctttatgggg ggaaatatcc cgggttacag cagtaccaat
    25381 cgtagcccct attcaaaagc ggaaattttc tctctgtttg ctgaaaacaa catggaactg
    25441 accgacagca ccatgctgac gccggggata cgtttcgatc atcacagtat tgtgggggat
    25501 aactggagcc cgtcgctgaa cctgtcgcaa ggtctggggg atgactttac cctgaaaatg
    25561 gggatcgccc gcgcttataa agccccgagt ctgtaccaga ctaacccaaa ctatattttg
    25621 tacagtaaag gtcagggttg ctacgcgact ggcgcgggta ccggcatcgg ctgctatatg
    25681 atgggtaacg atgatctgaa agccgaaacc agcatcaata aagagatcgg tctggaattt
    25741 aaacgcgatg gctggctggc cggcgtcacc tggttccgca atgattaccg caataagatt
    25801 gaagcgggta cggtgccgtt gcagcgtatc aataacggca aaacggatgt ctatcagtgg
    25861 aagaacgtgc cgaaagcggt cgttgaaggt ctggaaggca cgttaaacgt accggttagc
    25921 gacaccgtca actggacgaa taacgttacg tatatgctgc agagtaaaaa caaagagacc
    25981 ggcgaacgcc tgtcgattat tccacagtac acgcttaact ctaccctgag ctggcaggta
    26041 cgtcaggacg tttctctgca atcgaccttc acctggtacg gcaaacaaga gccgaagaaa
    26101 tatgattatc agggtaaccc cgttaccgga acagataagc aagcggtcag cccatacagt
    26161 attgttggcc tgagcgcgac ctgggacgtg accaaaaatg tcagcctgac cggtggcgtg
    26221 gataacctct ttgacaaacg tctgtggcgt gaaggtaacg cgcaaaccgt cagggatacg
    26281 caaactggcg cttatatggc gggcgctggc gcgtacacct ataacgaacc gggacgtacg
    26341 tggtatatga gcattaatac ccatttctga tggcaacctt ccctccctca ttcggggagg
    26401 gaattagcaa aagacgatgc tgacatctca ttttcccctt ccctttgccg gacacaggct
    26461 gcatatcgtc gactttgatg cgagcagctt tcacgaacac gacctgctat ggctgcctca
    26521 tcacgatcgg ctccggtctg ccggacgcaa gcgtaaagct gaacatctgg caggccgcat
    26581 cgctgccgtt catgcgctac gcgaggtggg cgtcagggcg gtgcccggta ttggcgacaa
    26641 gcgacagccg ctatggccgg acggcctatt tggcagcatc agccactgtg cgtcaacggc
    26701 gctggccgtc atatcccgac agcgtgtcgg cgttgatata gaaaaaatca tgagtcagca
    26761 cacggcgaca gagctggcgc cgtccattat tgatagcgat gagcgccaaa ttctccaggc
    26821 gagctcgctc ccttttccgc ttgccctgac gctggctttc tccgccaaag agagcgttta
    26881 taaagccttt tcagaccgcg tcacgctccc gggattcgat agcgcaaaaa ttacctcgct
    26941 taacgccacg cacatctcgt tacatctgct gccagccttt gccgccatga tggctgaacg
    27001 taccgtccgt acagaatggt ttcaacgtgg caatagcgtt attactctag tttctgcaat
    27061 aacgcgcttt ccccacgaca ggagcgctcc cgcttctata cttagcgcaa taccccgata
    27121 aatgagatcg ctatggcgct gaatgatttt cacgtttctg aaccttatac gctcggtatt
    27181 gagctggaga tgcaggtgat caatccacct ggctacgatt taagtcagga ctcttctacg
    27241 ctgatcgacg ccgttaagcc ccaacttact gcgggagaaa ttaagcacga tatcaccgaa
    27301 agtatgctgg agatggccac gggcgtctgc cgcgatattg accaggtggc ggcccaactt
    27361 tctgccatgc agcacgttat tttacaggcg gcgtcggaac accatctcgg catttgcggc
    27421 ggcggtacgc acccttttca aaaatggcag cgtcaggagg tctgtgataa tgagcgctat
    27481 caacgcacgc tggaaaattt cggctactta attcaacagg cgacggtttt cggtcagcat
    27541 gtccacgtcg gctgcgcgaa cggcgacgat gcgatttatc ttttacacgg gctgtcgcat
    27601 tttgtgccgc actttattgc gctctccgcc gcgtctccct atatgcaagg atctgacacc
    27661 cgttttgcct gcgcgcgcct gaatattttt tccgcttttc ccgataacgg gcccatgccg
    27721 tgggtcagta actggcaaga gtttgccgga ctatttcgtc gtctgtctta caccacgatg
    27781 atcgacagca tcaaagattt gcactgggat atccgcccca gcccggcctt tggcacggtt
    27841 gaggttcggg tgatggatac gccgctcact cttgatcatg ccatcaatat ggcaggattg
    27901 attcaggcga ccgcgcactg gctgctgacc gagcgtccct ttaaaccgca ggaacaagac
    27961 tatctgttat ataaattcaa ccgttttcag gcttgccgct atggtctgga gggcgtgcta
    28021 accgatgtct ataccggcga ccgccgtcgc ctggcagatg atacgctgcg tctgctggac
    28081 aacgttaccc cctctgcgcg taagctgggc gccgacagcg ccattgacgc gctacgtttg
    28141 caggtgaaaa aaggcggtaa cgaagcgcaa tatatgcggg agtttattgc cgacggcgga
    28201 tcgctgatag gcctggtaca aaaacattgt gaaatctggg cgggacaata gacagcatat
    28261 ttgccttacc aggcgatgtc ccggacaatg gcgttttaac ttacgtttaa caaagccatg
    28321 aaacacccgc ttgaatcatt gatgaccgct gccggtattt tgctgatggc gttgctctcc
    28381 agcctgctgc tgcccgcccc ttcgctcggc cttgcgctgg cgcaaaaact ggtcgggatc
    28441 tttcatctta tggatctcaa ccagctttat actttgttgt tttgtttatg gtttctgttg
    28501 ctcggcacgc tggaatatta tgttattcgc tttatctggc ggcgctggtt ttcgctggcc
    28561 gattaaacat ttcaatgcgt acggccatgc ttttctttac gataagcgcc tggcggcagg
    28621 ttgaacgtgc gggtaaaaat gcgcgtaaag gtttgctgcg aatcaaaacc atacttgaga
    28681 caaatatcat acaccttctg gtcggtgtcg cgcaggtcgc gcgccgccag ttttagcttc
    28741 cgttcacgca cgtagcgcct cagactctcc cctttgtact gcataaaaag gcgctgcagg
    28801 tgccacttgg aataccccgc atgacgggca atatcatcaa tacgtaacgg ctgattcaaa
    28861 ttatcatcaa tccactcgac aatcgtgtcg ataacctgag cggaaatggt catcgtgctc
    28921 tcccctctat caaactcgtc agcggctccc gcaccgcaca tttacggcaa cagcaataag
    28981 catagtaata accacacaaa ttgtgagacg gcttatcgca tggcctgcaa tatgcttttc
    29041 taccacttca tgcggcagcc cttgattatg agtgagtaag cactcattat agaaagcaaa
    29101 gatacgccgt caaggtactt ttcaaaggtt gacattcacc gttgcgacgc gacaacgggc
    29161 atgattcaat catgttttta cagacataag ggtaacgtgt agtggctcgt ccgaagagtg
    29221 aagacaaaaa acaagcatta ctggaagcgg caacccaggc gatagcgcaa tccggtatcg
    29281 ccgcctcaac ggcggtgatt gcgcgtaacg caggtattgc agaaggaaca ttatttcgct
    29341 atttcgcgac caaagatgag ctgattaaca cgttgtattt gcatttaaag cagaacctct
    29401 gccagtcaat gataatggag ctggatcgat ccattaccga tgccaaaacg atgacccgct
    29461 ttatctggaa cagttatatc agttggggtc tgaaccatcc cgcgcgccat cgggcgatcc
    29521 gtcaactggc cgtcagcgaa aagatcacca aagagacgga acaacgggcc gacgatatgt
    29581 tccccgaatt gcgcgattta tgtcatcgtt ccgttttgat ggtatttatg tcggatgagt
    29641 accgcgcctt cggcgacggc ctttttctgg cgctggctga aacaacaatg gatttcgccg
    29701 cgcgcgatcc cgctcgcgct ggcgaatata ttgcgctggg attcgaagcc atgtggcgcg
    29761 cgctgactcg cgaggagcaa taatggacgg tcaaacactg cacgcctgtg caaaacgctt
    29821 tgcgctggaa ctgcctttta ccgaacactg ctggcctttc ggcccacagt acgatgtgtt
    29881 taaagtcggc ggcaaaatat tcatgctgtt cactgaacat cactgtcgcc cagtggtgaa
    29941 cctgaagtcg gccccccaaa aatccctggt gaatcaacaa atttacccca gcattgcgcc
    30001 tggctatcac atgaataaga aacactggat ttcagtctat gcgggcgagg atatcaccgt
    30061 ctcgctactc aacgatttga taaatgactc atggaatctg gtcgtagacg ggctgcctaa
    30121 aagagagcaa ctgcgcctgc gaccgcgctg atgcaataac cgtttccgca ttttcctccc
    30181 ttatcttttt accgataacc cggtaccctg ctgatacaaa agggtactaa accaaccagg
    30241 agcatttatg gatatcgttt ctgtcgcctt aaagcgctac tccactaagg cgttcgatcc
    30301 cagcaaaaaa ctgaccgccg aagaagcgga taaagtaaaa acactactac agtacagccc
    30361 ctccagcacc aattcccagc cgtggcactt tattgtcgcc agtacggaag aaggcaaagc
    30421 gcgtgtcgca aaatccgctg ccggaaacta cacgttcaac gaacgcaaaa tgctggacgc
    30481 ctcccatgtg gtggtcttct gcgccaaaac cgcaatggat gacgcatggc tgcaacgggt
    30541 ggtcgatcag gaagatgctg atggccgttt cgctacgccg gaagctaaag cggcaaatga
    30601 taaaggtcgc cgctttttcg ctgatatgca ccgcgtctcg ctgaaagatg accaccagtg
    30661 gatggcgaag caggtttatc tgaacgtcgg caactttctg ctgggcgtcg ccgcgatggg
    30721 tctcgacgcc gtccccattg aaggtttcga cgccgaggtg ctcgacgctg aatttggtct
    30781 gaaagaaaaa ggctatacca gtctggtcgt ggtgccagtc ggccatcata gcatcgagga
    30841 tttcaacgcc gggctgccaa aatcacgtct gccgcttgaa accacactga cggaagtcta
    30901 atcccctgcc taagccggac gcccgtccgg cttttttcac ctttctgcca ggttccccaa
    30961 tgatcaatgg cgcgaagtgc caggttttac atcgttagtg ttaacttcct ctttcaacct
    31021 attgaaaata aatgatattt aaaactggca cgccgtttgc catatctgga taccccctat
    31081 ctggatgaag gagaaaacgg gtgagacatg tttatgtagc cagccatggc ccttttgccc
    31141 gcggacttat taacagtcta tcgctgctga ttggcgacga acacggcgtg acaccggttt
    31201 gcgcctacga tggcgatatt gtgtcaccac ggggttggcc ctccctggcg tgtcatcaaa
    31261 atcgggcgct aaacccaacg ttataacggg tttgattgcc atcgcttaac cctgccgttt
    31321 gcgccagccc ggcgaaagcg gacactgttg ccgacagcgg aaaatctgcg ccaatcgcga
    31381 tatcaaccca gtttttatcc tgcgctttcc cggcacggct aaacgtcagc gcggtcgatt
    31441 taaggccgcc gttcgccaca tacgtatcat cgccaaactg acggcgataa ttaatctgcg
    31501 cccaggaatg aatgatactg tggcgaagat ccagacgcca acccacgctg cccatctgcg
    31561 aatgggcgtt ttggtcgcca aaacgcattg atgtactggt attgagcttc tcgctataac
    31621 cattaacgtg gctgtaatcc catgcatatt gcagcatcgg cccggtcgtt aaccacggca
    31681 tcatgacaaa atcataaccg ctggttaacc tcgcgcccca cagccgaccg ttggtttcgc
    31741 cctcttccac ccgtcttagc gcaccgagcg tgatactgcg ctgaatgtta ctgaatttag
    31801 cggacaggta gtgtaaatcg ccatccagcc acgcctgacc ggcgcgtaaa tggctgaata
    31861 cggcggcctg aaaaccgcgg gcgtcataac gataattatc gtcaggatgt tgcttatcca
    31921 gagaaccggc tatcagccct cccagcagta cctgctcgtt aagctgataa tcgacgccaa
    31981 ccgtcagatt attatgatta ccgttcccgt cggcctcatt attatcataa cgttgatatc
    32041 ccccgctgta tccgccgaac atgcccagtg aaccaacagg attttccccc tggcgaagct
    32101 gctgataacg gctgtcaagc gtggtacgac tgccttgcgc catcgactga acgctttggt
    32161 tcagatatgt cgcctgtacc ggcgcggcaa tgatcgactg aatatattgc gcaataatgg
    32221 tatggacctg cggaccggga tgtaaatgat cggcaaacag atagtcctgc gacgcattaa
    32281 atccaggcat tgccgaggag cacaccgaag cggatacgcc cggcgggcag gccatgccta
    32341 cggtatttgt cagaccaaac gcctgcgggt tggcaagaat ttccttaaag aggccgttga
    32401 tatcggcacg ggctatattg ccgccgtgtt gctccagccc cttctcttcc atctgattat
    32461 aataatcggt cagagctgac gcctgctctg ccaccttttc atagcccgcc agcagttgct
    32521 caacgagcag ttgctgaata aacggattgc tgcttaccgt tgcagccgcc gccagcaacg
    32581 ccttgcggat cgcctgttgc cgactggcga aatcgggcgt agctccctcc gccagcgcct
    32641 ctaacgccgc ttttagcgcc gggggcgccg ctgcgcccag cccggcggtg attaccgcct
    32701 ccagaagctc tggcgtcgca ctaatatccg gtacgtttgg caccacgacc agcccggcgc
    32761 cggcatccag taacagccct acctgcgccg ccgcgctagt ggcgctatta ccggctattt
    32821 gctgtgccat ggcaggtcgc gcgatggccg ccgccagatc gtttccgccg acccagtgaa
    32881 tatacaaacc gttgtggtcg gcttttcccc ccgtattggc aagccactgc cgtacctgat
    32941 ccgcggtatt atcctgcggg tttaattccg gggccgtcat cgcgccgcca gcggcataat
    33001 tagaaccgcc attgctggaa gggcttaatg ccagcccata tcgttcggcc aactgttcgt
    33061 cgtagagctt attttgacca ctatcccagg tccagcgacc gttatttccg gtatcgctaa
    33121 ggctatcgcc aatcaccgta agagagtcaa acgcacaggc agataatggc gcggccagcg
    33181 ccagcgagag tatgccgtat tttagcaggg tacgcttttg ggtcatccga tgttccttaa
    33241 tgttattgtt gataggtacg acggttctaa tcattatccg acagagatat tgcaatcgtt
    33301 ttaaacattc tggttaaaaa gttttcattc attgttgacg gactggcgcc tgttcaaaaa
    33361 gagggaaccg cgtaaaataa cgacgtttat agggcgctgg ataaaatata gcgtatggat
    33421 aaccccagag gcgcttttac ccgtctgttg ctgattatgc ctgaagcgca ggcgtcctga
    33481 tttgcataaa tgccattcag cagtcatcat aggctgctgt ttataaagga gagattatgc
    33541 aggaattgat atcccaggta gaagatttag cgggaattga aatgaatcac accacgtcgc
    33601 tggtggtgat atttggtatt atttttctga cagcagttgt cgtgcatatt attttgcact
    33661 ggatagtact gcgcgctttt gaaaaacgtg ccagcgccag ttcccgcctg tggctgcaaa
    33721 ttattaccca gaataaatta ttccatcgtc tggcttttac gctacaaggc atcattgtca
    33781 atattcaagc cgcgctctgg ctacaaaaag gcagtgaggc tgcggatatc ctgacgacct
    33841 gcgcgcagtt atggattatg acctacgccc tgctgtcgtt attttcgctg ctggacgtga
    33901 ttttcaatct atcgcaaaaa tggcccgccg cctctcagtt accgctaaaa ggaatatttc
    33961 agggcattaa gctcatcggc gcaattatcg tcggcattct gatgatctca ctgctgattg
    34021 gccagtcacc agcaatttta atcagcgggc tgggcgcgat ggccgcggta ttaatgctgg
    34081 tctttaaaga cccgattctt ggcctggttg ctggtataca gctttccgcc aacgatatgc
    34141 tcaaactggg cgactggctg gagatgccaa aatatggcgc agatggcgcg gtcattgata
    34201 ttggcttaac cacggtaaaa gtacgcaact gggataatac catcaccacc attcccacct
    34261 ggtcgctggt ttccgactcg ttcaaaaact ggagcggcat gtctgcgtcc ggcggacgcc
    34321 ggattaaacg cagcattaat attgacgcga ccagtatcca ttttctggat gatgatgaaa
    34381 aacagcggct gttaaccgcg caactgttaa agccgtacct taccagccgt catcaggaaa
    34441 tcgatgaatg gaataaacaa ctggatgcgc cggaatcagc cttaaatcac cgccgaatga
    34501 ccaatatcgg gacatttcgc gcctatctga acgaatattt acgccaccat ccgcgcatcc
    34561 gtaaagacat gacgctgatg gtacgccaac tggcgcctga cgatcatggt ttgccgatag
    34621 agatctacgc ctttaccaat accgtcgtgt ggctggaata tgagagcatt caggccgata
    34681 ttttcgacca tatttttgcc gtggtggaag agttcggctt gcgtattcat cagacgccga
    34741 ccggcagcga tattcgcgcg ctgtcaggga cattgcgcca ttaatggatt gcccgatcgc
    34801 atgagcatgg gatcgggcaa aaaagttaat gagccttacg gcgcaaaacg gtaaacgcga
    34861 taaacagaaa tacaatccat accggcagca aaatcgccga caatcgcata tcgtccatcg
    34921 tacacattaa caccagaatc agcgccagaa acgcaatgca caaatagttt ccggcgggat
    34981 agaacagcgc cttaaattgc gtctcgcgcc ctttacgacg catcgccgcg cgaaaacgta
    35041 aatgcgcgag acagatcatt atccagttta gcaatagcgt cgcgacaacc agcgccatca
    35101 acaggctaaa cgctttttgc ggcaacagat agttgatcag caccaccagc gaggtaatcg
    35161 ctccggacag catcagcgag ttcaccggca cgccgcgatg gctgacgcga gttaaaaatt
    35221 tcggcgcgtt gccttgtacg gacaggccga acagcattcg gctattcgaa taaacgccgc
    35281 tgttatacac cgaaagcgac gcgaccagga taacgaaatt cagcgccgaa gccaccacat
    35341 tactgtccag gttatggaag atcatcacaa aagggctgct attggatttc acctctaccc
    35401 atggatagag cgccagcaac accaccagcg aaccgatgta gaacagcaaa atacggtata
    35461 ccacctgatt caccgctttc gggatgcttt tttgcggatc gcgcgcttcc gccgcagtaa
    35521 tgccgatcag ctccagtccg ccaaaagaaa acataatcac cgccagcgac agaagcaaac
    35581 catgccaacc ggtagcgaag aaaccgttat aacgccagag gttatcaatg ctggcatgtt
    35641 cgccgccgtg gccggagaac agcagccaca gaccaaaacc tatcatgccg ataatcgcca
    35701 gcactttaat gagcgcgaac cagaattccg tttcgccata cagacgaacg ttcaccagat
    35761 tcacggcatt aatgataata aaaaacaccg ccgcccatac ccatgttggt acgtcaggca
    35821 gccagtactg catatagatg cccgccgcgg tcagctccgc catcccgacc agcacaaaca
    35881 tgacccaata gttccagccc gacaaaaagc ccgcaaacgg cccccaatat ttccaggcga
    35941 agtgggcaaa cgatccggaa accggctctt ccacgaccat ttcacccaac tggcgcataa
    36001 tgagaaaagc gataatcccg gcaacgccat agcccaacaa aacagccggc cccgccattt
    36061 gaatcgccgg gccgatgccc agaaacagtc cggtgccaat ggcgccgccc agggcgatta
    36121 gctgaatatg gcggttttgc aacccccgtt gaagcgtcgg ttcattcttc gacgcggcat
    36181 ccgacacgct ggcgccggat gcagttgacg cgtttttcac gtcctacccc tgtatcgttt
    36241 ttattgaggg gcacctttta acatttcgct ctcgctgccg caaggcgcaa tcgtttgtca
    36301 aggctcaact ccggacgtta acgttatcgt gtaaaaaaag atgtcgcggg gagtaaaaag
    36361 aaaagagtac gcgccgatat agaacgttac gggtgacaga cgccgggtat aaaatatgtg
    36421 aataactctg gacgaaaagt acgacaccct acagaataca tttagtattt tttcagtatt
    36481 ttcaaaaagg tgaatcagac ctggtatctg ttatccattt ttgagccacg ccaggcgtca
    36541 acgtcatgaa taagatcatc aaacgtttag agatcattaa aagcgccatc gaacttgagg
    36601 acgaagagat tatccgtcag cagctcatct acctgaaaaa tgagccgcag gatgccgtaa
    36661 tcagcgcgat tgcccaggcg attgaaactc gtcgattcag tgacgccatg caagagatcg
    36721 ccgcctggct acaggctcaa cgggcgctct cgacgtggca agatccctct attgccgcca
    36781 gtaaactgga gctgaaagcg cttgaagccc aacttcgcga tctgattgac aaacgaaatg
    36841 cgcgggtaca aatcctcgac gatttcaacg acctctatca tctgcgtctc gggccgttga
    36901 tgagccgtat tctggagttg cgtaaacagc tcgcggtgag tatgcagcgt aagcaagagg
    36961 ccgaaataaa acgccgggaa aaggattatc aatcctgcct gcaatttatt tcccaggccg
    37021 tggatcaact ggcaacgcta aaacagcagt ggacaggatt gaatgccgcc tcgcgcgaag
    37081 cggtgggcat ccgtcagcga atccagcagc agacggaatt aatcaccgcg ttgctggcgg
    37141 aaattcgcga gctggaagcg gatttttccc atcaggacga cagcgcattc cgccaggcgc
    37201 aggaaaatgc ggaacagaac tatcaccagt accgggagca gcagcaggaa gcgtaattcc
    37261 gctacgcccg cgatcaacgt ttgtcggcag acgaacgcag tgaattaaaa cgtttgtggc
    37321 gtcaggccag ccgcctgtgt cacccggatg tggtcgccga tgaattgaaa gaaaaagcgc
    37381 accagatgat ggtacagctt aatcaggcgc ggcagaatgc cgatctggcg gcaattcgcg
    37441 cgttattgac gcagctgcaa agcggtctgg aaccgatgat ggcaagcgac aggctaaata
    37501 acctggaaca tctgcgccat aaaatacgcc agctccgcac gcaaatcgac gcgctgttga
    37561 aagagataac gcagctggaa acggaaaatg cctggcggct cgcctcttcc gttgcgaata
    37621 aggaagccta tttctccgag caggaacggg cgctaaccga aattcgcaat acgctggagg
    37681 cgcaggttca acaggtggaa caggaacttc tggcagggta gtccatcatt catcaacaca
    37741 ttgtcggatg gcgcaagcgc cacccgacga atcgcggcat aaagagagta agagggtcgc
    37801 tactggcgct gtaaaagtaa cgaacgggcg gagtccgcca tgatcatcac cgcacctgcc
    37861 agcattaacg tatcttttaa taccagccgc ccggcgcccg ataaatacgg gaaaccataa
    37921 tgcgcatcgc ccagcggcat aacccaggcc tccggcgtgg tgattaaaaa cgacagcgtg
    37981 acaaatggcg tcaggaatgc cagcacgccg cccgccagcc ctaaccagcg gctaacaggg
    38041 ttagccagta ccagcgccgc gataatcaat tccaccacgc ccagaccatc cgaaaacgca
    38101 tacgtattat tggccgtttg ccaggcgcgt tcctccggtt ttagttcgcc ctcatgagtc
    38161 agatgctgac gatattcttc aggatgttca tagaaaaaag acataaacgg gctgttcgcc
    38221 acaaacgggg taatactgtc tgcctcatag ggcacaaatt ttagtagtcc aatccagata
    38281 aaaacgatgg cgatactcag gcgaattaat gttaatccca gccgatcccc ctgacttaac
    38341 agacgaagat atttatccat ctcaggctct ccttatttat ataatatcgc agtggcgtaa
    38401 cccgtattat caatacgcat tgacgtaatt ttccatgacg acgcctgttt actttgcgcc
    38461 agtctggcaa tagcgtcttc aagcattgac ggtgttgctg acaccgcaga aacgctgata
    38521 tattcaacgt cagttagcgg ctgggcggag gcggaaaacg ccagcggcgc agccaataat
    38581 gaagcaataa gtgtggtaac ttttaacatc gagatttcca gtcgtgggtt atttcaatgg
    38641 tgttataata cgttatgcct gactaaagcc ttttctttca gacgccagca tatttgtcct
    38701 gtcgtatttt tatggtctga caggcaaaaa aaagccctga ttaacagggc tacattattt
    38761 atgttttact taatgagaga gaagagatcg tttaaagact cactcattgt aggatgggta
    38821 aatatctggt cgcgtaacac cgtataaggt aaatctgcat ccataacggt tttaacgata
    38881 ttaatcattt catgagaatc gacgcataac aatgacaccc ctacaatacg ctgcgtattc
    38941 acgtccacta ccgcttttag tacgccacgg gtatcattca taacacgggc gcgagggatc
    39001 gccgccaccg gtaatgtcac cacctgcacc gttgcgccgc ttgcccgcgc ttgttcttcc
    39061 gtcagcccga cacgagagag cggcggcgtc ataaagacgg aatacggtac gttctggcga
    39121 tcgcgggtac tgcgtttgcc atctcccaat aacccgtcgc gtacaatacg aaaatcatcc
    39181 agtgaaatat aggtaaactg caacccaccg gtaacatcgc ccatcgccca gatattgtcc
    39241 gccgtggtac gcaggtaatc atccacgatg atcccgccgc gttcgttcac cgccacaccg
    39301 gcgttctgca actgtaagcc agccgtcgcc ggttttcgcc ccgacgccac cagcagggca
    39361 tccacaagat gcgcgccttc cggcgtttca acttgtaccg cgccctccgt tgaggatacg
    39421 gcctgtacgt tggcgtttaa aattagctcg acgccctttt cctgtaaaat gtgggtaatt
    39481 gcctgcgcga tatcccgatc ttcacgaggc aggaattgcg gcgctgcttc aaagatagtg
    39541 accttcgtac cgaagttagc gaacattgag gcaaattcaa ggccaatata accgccgcct
    39601 aaaatcccca gccgcgccgg acgctggctc aggcttagta gcccggtgct atcgaacacc
    39661 cctgccgtcg ttgttaagcc cgtaatagcc gggatcaccg actctgcgcc agtattaatg
    39721 aagatctttt ctccccgtaa cacccgctcg ccgtccgcct gaaatacccg taaggtatgg
    39781 ttatcaataa actccgccct tccctcaatc acatcgacat tgtccaggtc ggcaagatta
    39841 tgaaaatttt tgtcgcgtaa aaaatttacg accgccgctt tgcgttgcat ggcgacagaa
    39901 aaatcgccct cacgttccgc gtcatacacc agcgttttcg ttggaataca gccaatgttg
    39961 atacaggttc cgccaaacat actggcggac tgttcgataa tcgccacgcg ccatcccgtc
    40021 ttcgccagag ttgccgccaa cgtttttcct gccttgccaa aaccaataat gagcgcctga
    40081 tactgtgtca tcttctttct ccgccaaatc accatctgtt tgtcaggaca agtataaata
    40141 acgtcaaaaa agacagggtt atccgtaacg cgtcattttt tgtcttatcg tctaaattag
    40201 cggttaggaa aaacaaggat agaaatgaca ttgagtccga aatatagtga tcagagacag
    40261 aaatggttat ccttattttt gaaaataaat ctgttctgga gtctatatgg atgcgcttag
    40321 tcggctattg acgcttaacg cccctcaggg ctcaatcgac aagaattgcc cgttaggcgg
    40381 cgactggcag ttgccgcacg ccgctggcga gctatcggtg attcgctggc ataccgttac
    40441 gcagggcgaa gcgcaactgg aaatgcctac cggcgacgcc atgacgctta cgccgggaaa
    40501 ggtggtgatt ctgccgcaaa actccgccca ccgtttgcgc cagtctggcg aagcaccgac
    40561 acatatcgtg tgcggtagtc tacgtctgca cacgacgtca cgttatttcc ttaccgcgtt
    40621 gccggaagtg ttatgtcttg ccccgccgcc gcatagcccc gccagtatct ggcttaacgc
    40681 cgccatttcg ctgttacagc aggagtcaga acgccattta cctggcgctg atgtcttata
    40741 cagtcagcag tgcgccacgt tgtttaccct cgccattcgc gactggctat cgcaggctgg
    40801 cacggcgaaa agcgtgctca atttattgct gcatccccgg ctgggccgcg tgatcctgca
    40861 catgctggaa acaccggcgc atccctggac ggtcgaaacg ctggtgcaac gggtacacat
    40921 gtcgcgggcg agcttcgccc agctatttcg cgacgtgtcc gctacaacgc ccttagccgt
    40981 gttaacaacg ctgcgcctgc aaatcgccgc ccagaccctg tcgcgtgaag cgctgccggt
    41041 gatggtgatt gccgagtcgg taggttatgc gagcgaatct tcttttcaca aagcgtttgt
    41101 ccgtgaattc ggttgtacac caggcgagta ccgcaaacgg gtcaacgcgc ttggacgata
    41161 aacgtatact gaacccgcct acagtttgac gccgcaggcg ggcgacacac attatgccgc
    41221 aaggcgacga tgcctgcgca gccacatcag cttgtaggct gccggaatga tgaacagcga
    41281 cagcagcggc gcggtaatca tgccgccaat catcggcgtg gcaatacggc tcatcacctc
    41341 agaacccgcg ccttttcgat cgtttttatc gcgttgctcc ctcccgccag cgtaaagggg
    41401 aaggccgcgg tataggcctg gcaattgtaa aatccatcgt cattgcgcat cagggaaaag
    41461 tttctgtcac ctccgatacg cgctactcgt tttattttga cattacccaa acacctccgt
    41521 tgaactgtag cgatagtgaa aggcgctatc actagccagc aaaataatct gatataatcg
    41581 tcattatccc gtcacgcgcc aaacccaaca actgttttat tatttctctt attaacccac
    41641 accggagaaa taagataaat aagtttacat cccttttagc tgtcgttttt atttcagctg
    41701 gcgtacacac cgcagagaaa atggaatccc gccaattatc cgctacagca catgagatga
    41761 tgaataacgg tgacgccttc gcgcatcagc aaatggctca gacacagaaa cccagcgccc
    41821 cgactactgt ggaaaatgcg acaccctttt ctgaaatgga cgactatgaa aaagcaatgg
    41881 tcatccatca atcgatgaat aatgcccatt ctttctccca cgagatccag gctgaggagc
    41941 accataaaca gattaaacgc aattagttat ttgcatatta gcgtcacgta ctgcggatgg
    42001 cacaacgtcg cccccgcaga agcttacgga ttaacataat tttgagaggt taaatggcgc
    42061 gccctgcagg attcgaacct gcgacccacg gcttagatgt tcctggaact acctgagcta
    42121 acaacaagtt atcccattac cacggcgctc actcgcccca tcttcgaaaa acatgcaaag
    42181 ctttgtgtgt cccgtttttg tcccaaccca ctcagcaatc agcagctcca attgatcggt
    42241 aacaacgatc aattaataag acaacaataa gttcaagcta tcaaatataa cattattgat
    42301 cgtttatatc gaaaaaagca atttgtagta ctatactcca gacctttccg aatccgctga
    42361 ttttcataat gttgaagtta ttcgctaagt acacatcgat cggtgttctt aacacgctta
    42421 ttcattgggg cgtatttgct ttttgtgtgt atgggatgca tacgcatcag gcgctggcga
    42481 acttttccgg ttttgttatc gccgtatcgt tcagcttcta tgccaatgcg cgcttcacct
    42541 ttaacgccag caccaccacg cttcgctaca tgatgtacgt gggatttatg ggaacactga
    42601 gcgccgttgt tggctggatg gctgacaaat gttccctgcc gccactcctt actcttgtca
    42661 ccttttcagc tatcagcctg atatgcggat tcatttattc aaagttcatt gtctttaggg
    42721 atgcgaaatg aaaatctcgt tagtcgttcc ggtcttcaat gaagaagcca cgatacctat
    42781 tttctataaa acggttcgcg agtttgaaga gttaaaaccg tatgaagttg agattgtttt
    42841 catcaacgac ggaagcaaag atgcgactga atcaataatt aacaaaatag ctgcatctga
    42901 tccgctcgtt attccgcttt cgtttacgcg aaacttcggt aaagaacctg ctcttttcgc
    42961 gggtctcgac catgcaaccg gggatgcggt cattcctatt gatgtcgatt tacaggatcc
    43021 gatagaagtt atcccccatc tcattgagaa gtggcaggct ggcgcggata tggtgctggc
    43081 taagcgctca gaccgctcaa ctgacgggcg catgaagcgt aagacagctg aatggtttta
    43141 taagctgcat aataaaatca gcaatccgaa aattgaagag aacgtcggtg atttccggtt
    43201 aatgagccgt gatgttgtcg aaaatattaa acagatgcca gaacgtaatc tgtttatgaa
    43261 aggcgttctg tcatgggtgg gcggcaagac tgatgtagtt ggatacgccc gcgctgagcg
    43321 tgttgccggc gattcaaaat tcaatggctg gaaattatgg aatctggcgc tggaaggaat
    43381 aacttctttc tcaacatttc cgctccgcat atggacgtac attggattgt ttattgcagg
    43441 tatgtcgttc ctttacggta catggatgat tatagataaa ttaatatttg gaaataatgt
    43501 tcctggctac ccgtctcttc ttgtttctgt acttttcctg ggtggcgttc aattgatagg
    43561 aataggtatt cttggggaat atattggcag gatttacata gaaactaaaa aaaggcctaa
    43621 atacataatt aagaatggga agaaaaatgg ttaacaatag attaaaaatg gtaattgcta
    43681 tccttatagt tttctcattg gtgtattcaa taggatttat tacaccaatg aactctgatg
    43741 actatactta tgccctaaga gagctttcgc tttctagcgt aaaaatgcac tatttgggat
    43801 ggagcggaag ggttgtgtca gatacgctca gcacatctct attaaagttt ttctccccgc
    43861 atatttacaa tgcaataaac tcagcagcgc taacattaat ggtgttgtgc tggacaatga
    43921 tcccagcgac attaacaaag tcgtcaccgt cccc
//
LOCUS       DAJVKX010000027        43722 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000027 DAJVKX010000000
VERSION     DAJVKX010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 43722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43722
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.027"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            21..1391
                     /gene="proY"
                     /locus_tag="OPY25_001430"
     CDS             21..1391
                     /gene="proY"
                     /locus_tag="OPY25_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HCS0927077.1"
                     /translation="MESNNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPAVPHWIWVLSVVLIICAINLMSVKMFGELEFWFSFFKVATI
                     IIMIVAGIGIIVWGIGNGGQPTGIHNLWSNGGFFSNGWLGMIMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKVFAKTSRRGIPWVT
                     VLVMTIALLFAVYLNYIMPENVFLVIASLVTFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVVTTIAGLIFLVFIIALIGYHPNTRISLYVGFAWIVLLLIGWIFKRRRD
                     RQLAQA"
     gene            1553..3370
                     /gene="malZ"
                     /locus_tag="OPY25_001431"
     CDS             1553..3370
                     /gene="malZ"
                     /locus_tag="OPY25_001431"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HCS0927078.1"
                     /translation="MLNAWHLPVAPFVKQHNDKLTITLWLSGENPPSRVTLRSEFDNE
                     EISLAMRKQRRQPQPGVTAWRATLNIALGQPRRRYSFKLLWHDRQRWFTPQGFSCFPP
                     ARLEQFAVDVPDSGPQWVADQIFYQIFPDRFARSATREADQDRVYYHHAAGQEIVLRD
                     WDDPLTPQAGGSTFYGGCLNGICEKLPYLKKLGVTALYLNPVFTAPSVHKYDTEDYRH
                     VDPQFGGDRALLRLRRETQAQGMRLVLDGVFNHSGDSHAWFDRHNRSTGGACHHPDSP
                     WRDWYSFSPQGVALDWLGYPSLPKLDYQSETLVDEIYRGEDSIVRHWLKAPWNMDGWR
                     LDVVHMLGEAGGARHNLQHVAGITRAAKEAQPEAYIVGEHFSDARQWLQADAEDAAMN
                     YRGFTFPLWGFLANTDIAYEPQHIDARTCIAWMDNYRAGLSHQQQLRMFNQLDSHDTA
                     RFKTLLGKDAARLPLAVVWLFTWPGVPCIYYGDEVGVDGANDPMCRKPFPWDERKQDG
                     NLLALYQRMAKLRQSSLALRRGGCQALYAEGDVVVFVRVYQQQRALVAINRGEACEVA
                     LEALPLLNVAGWQCKTGSGDIREGRLSLPAISATVWMNR"
     gene            complement(3442..4044)
                     /locus_tag="OPY25_001432"
     CDS             complement(3442..4044)
                     /locus_tag="OPY25_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCS0927079.1"
                     /translation="MVLVTRQAPDFTAAAVLGSGEIVDKFNFKQHTNGKTTVLFFWPM
                     DFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEFVHNAWRNTPVDKGGIGPVKYAM
                     VADVKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
                     LQFHEEHGDVCPAQWEKGKEGMNASPDGVAKYLAENISSL"
     gene            complement(4254..4835)
                     /gene="acpH"
                     /locus_tag="OPY25_001433"
     CDS             complement(4254..4835)
                     /gene="acpH"
                     /locus_tag="OPY25_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HCS0927080.1"
                     /translation="MNFLAHLHLAHLADSSLSGNLLADFVRGNPATHYPPDVVEGIYM
                     HRRIDVMTDNLPEVREAREWFRHETRRVAPITLDVMWDHFLSRHWTQISPDFPLQAFV
                     GYAHAQVATILPDSPPRFVNLNDYLWSEKWLERYRDMDFIQNVLNGMANRRPRLDALR
                     DSWYDLDAHYDALEERFWHFYPRMMAQAARKAL"
     gene            4929..5993
                     /gene="queA"
                     /locus_tag="OPY25_001434"
     CDS             4929..5993
                     /gene="queA"
                     /locus_tag="OPY25_001434"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCS0927081.1"
                     /translation="MRVTDFSFELPESLIAHYPQPERSRCRLLSLEGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGTELLLGDDESIHATMTARHGALFEVEFNDPRPVLDILNAIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLAALREKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQEVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKSDLIEPF
                     FGDTQIFIYPGYQYKVIDALITNFHLPESTLIMLVSAFAGYQHTMNAYKTAVEQKYRF
                     FSYGDAMFITCNPQAISERP"
     gene            6190..7317
                     /gene="tgt"
                     /locus_tag="OPY25_001435"
     CDS             6190..7317
                     /gene="tgt"
                     /locus_tag="OPY25_001435"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCS0927082.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKHKSDISPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD"
     gene            7340..7672
                     /gene="yajC"
                     /locus_tag="OPY25_001436"
     CDS             7340..7672
                     /gene="yajC"
                     /locus_tag="OPY25_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCS0927083.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAEAGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            7700..9547
                     /gene="secD"
                     /locus_tag="OPY25_001437"
     CDS             7700..9547
                     /gene="secD"
                     /locus_tag="OPY25_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HCS0927084.1"
                     /translation="MLNRYPLWKYIMLVVVIIVGLLYALPNLYGEDPAVQITGVRGVA
                     ASEQTLIQVQKTLQEEKIPAKSVALEEGAILARFDTTDTQLRAREALMSVLGDKYVVA
                     LNLAPATPRWLAAIHADPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDSKARDEAIAYLTPRHRDLVISSQSGNQLRAVMTDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAAAGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGISNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     KQGLEACLAGLVVSILFMIFFYKKFGLIATSALVANLVLIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAINEGYAGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIIGTRAIVNLLYGGKRVTKLSI"
     gene            9558..10529
                     /gene="secF"
                     /locus_tag="OPY25_001438"
     CDS             9558..10529
                     /gene="secF"
                     /locus_tag="OPY25_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HCS0927085.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDFWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEMDVMREALQKAGYEEPQLQNFGSSHDIMVRMPPTE
                     GETGGQVLGSKVVTIINEATNQNAAVKRIEFVGPSVGADLAQTGAMALLVALISILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLVVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            10676..11041
                     /locus_tag="OPY25_001439"
     CDS             10676..11041
                     /locus_tag="OPY25_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCS0927086.1"
                     /translation="MKNLINWFEIPVTDMARAIAFYEQVMQISLRRETMDGADLAVFP
                     YAEPGPGGALIKQDDVAPVAQGVVIYLHTADLLASIERVVLAGGKCVLEPMVPGDDIG
                     TIALFIDSEGNRIGLHQPA"
     gene            11067..11759
                     /locus_tag="OPY25_001440"
     CDS             11067..11759
                     /locus_tag="OPY25_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HCS0927087.1"
                     /translation="MTRRADRLFQIVQILRGRRLTTAALLAQRLAVSERTIYRDIRDL
                     SLSGVPVEGEAGSGYRLMAGFDLPPLMLTHRESEALMVAIRLLKTWGGDSLSRELESA
                     QEKVLAILPEESRRKAEQTRIYAPDLGTSPHSRSAFDLIHQAVSAQQVLALHYRDEAG
                     HLSSRDIQPLGLFFWGEHWLLVAWCERREDYRCFRLDRCLQITPLNRRFRETIDRSLR
                     DFLRKVEHEKMP"
     gene            11929..12276
                     /locus_tag="OPY25_001441"
     CDS             11929..12276
                     /locus_tag="OPY25_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HCS0927088.1"
                     /translation="MAIIPKNYARLESGYREKALKLFPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGSTVIAGEDAQKDVGEATYN
                     PFADLKAMMNKKK"
     gene            12719..12826
                     /locus_tag="OPY25_001442"
     CDS             12719..12826
                     /locus_tag="OPY25_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HCS0927089.1"
                     /translation="MTLTELSITIWHDLAAPTLVGIATGLFLGWWHRRK"
     gene            complement(12909..13772)
                     /locus_tag="OPY25_001443"
     CDS             complement(12909..13772)
                     /locus_tag="OPY25_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HCS0927090.1"
                     /translation="MKKTLLAVSAALALTSSFTANAAENDQPQYLSDWWHQSVNVVGS
                     YHTRFSPKLNNDVYLEYEAFAKKDWFDFYGYIDIPKTFDWGNGNDKGIWSDGSPLFME
                     IEPRFSIDKLTGADLSFGPFKEWYFANNYIYDMGDNKASRQSTWYMGLGTDIDTGLPM
                     GLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPITDLWGGKLSYIGFTNFDWGSDL
                     GDDPNRTSNSIASSHILALNYDHWHYSVVARYFHNGGQWQNGAKLNWGDGDFSAKSTG
                     WGGYLVVGYNF"
     gene            complement(14072..14611)
                     /locus_tag="OPY25_001444"
     CDS             complement(14072..14611)
                     /locus_tag="OPY25_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HCS0927091.1"
                     /translation="MTRRYLRILLVGSLLSLTACAPQSEVRQMHQSISTLNKEMTQLN
                     QETVKITQQNKLNADSTRGVYLLPGANTPARLESQIGTLRMTLLEITPVADGAHATLR
                     IQGKSRDPLPAFSATVEYGQIQGTTENYQEVNAQSLLVNAPASLLAPSDVNIPLPLKG
                     ITPAQLGFIRIHDIQPVNQ"
     gene            14763..15212
                     /gene="nrdR"
                     /locus_tag="OPY25_001445"
     CDS             14763..15212
                     /gene="nrdR"
                     /locus_tag="OPY25_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HCS0927092.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVIKSNDVREPFNEDKLRSGMLRALEKRPVSADDVEMALNHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKDFGEEIARLQD"
     gene            15216..16319
                     /gene="ribD"
                     /locus_tag="OPY25_001446"
     CDS             15216..16319
                     /gene="ribD"
                     /locus_tag="OPY25_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HCS0927093.1"
                     /translation="MQDEFYMARALKLAQRGRFTTHPNPNVGCVIVNNGDIVGEGYHH
                     RAGEPHAEVHALRMAGAKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIAVSHGLMMSEAEALNKGFLKRMRTGFPYLQLKLGASVDGR
                     TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWAELDASTQAS
                     YPQENLRQPVRIVIDSQNRVTPAHRIVQQPGETWIARTQEDSHAWPDSVRTISVPAHN
                     GHLDLVVLMMQLGRQQINSIWVEAGPGLAGALLQAGLVDELIVYVAPKLLGTQARGLC
                     ELPGLEKLADAPQFTFSEIRHVGPDVCLHMVSA"
     gene            16408..16878
                     /gene="ribE"
                     /locus_tag="OPY25_001447"
     CDS             16408..16878
                     /gene="ribE"
                     /locus_tag="OPY25_001447"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HCS0927094.1"
                     /translation="MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQV
                     KDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLA
                     SVAQDSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            16899..17318
                     /gene="nusB"
                     /locus_tag="OPY25_001448"
     CDS             16899..17318
                     /gene="nusB"
                     /locus_tag="OPY25_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCS0927095.1"
                     /translation="MKPAARHRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLSGVATNSAYLDGLMKPYLSRLLEELGQVEKAVLRIALFELSKRSDVPYKV
                     AINEAIELAKTFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            17397..18374
                     /gene="thiL"
                     /locus_tag="OPY25_001449"
     CDS             17397..18374
                     /gene="thiL"
                     /locus_tag="OPY25_001449"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HCS0927096.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVETGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPEVDEPWLEA
                     FSDSLFALLNYYDMQLIGGDTTRGPLSMTLGIHGYIPAGRALKRSGAKPGDWIYVTGT
                     PGDSAAGLAVLQNRLQVSEETDAHYLIQRHLRPTPRILHGQALRDIASAAIDLSDGLI
                     SDLGHIVKASGCGARVDVDALPKSDAMMRHVDDGQELRWALSGGEDYELCFTVPELNR
                     GALDVAIGQLGVPFTCIGQMSADIEGLNFVRDGMPVTFDWKGYDHFATP"
     gene            18352..18867
                     /gene="pgpA"
                     /locus_tag="OPY25_001450"
     CDS             18352..18867
                     /gene="pgpA"
                     /locus_tag="OPY25_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCS0927097.1"
                     /translation="MTILPRHKDVAKSRLNLRNPWHLLATGFGSGLSPVVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMFGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTTDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGII"
     gene            complement(18971..19945)
                     /locus_tag="OPY25_001451"
     CDS             complement(18971..19945)
                     /locus_tag="OPY25_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCS0927098.1"
                     /translation="MQYNTLGNTDLRVSRLCLGCMTFGEPSRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARRDEVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLTRLGMEYVDILQIHRWDYTTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALALQKQHGWAPFVTMQDHYNLIYREEEREMLPLCWQEGVAVIPWSPLARGR
                     LTRPWGETTARLASDDVGKNLYDESDKNDAQIAERLAGVSEALGATRAQVALAWLLSK
                     RGVAAPIIGASREEQLDELLNAVDLTLKPEQIAELETPYKQHPVVGFK"
     gene            complement(20002..21864)
                     /gene="dxs"
                     /locus_tag="OPY25_001452"
     CDS             complement(20002..21864)
                     /gene="dxs"
                     /locus_tag="OPY25_001452"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCS0927099.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKDRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLARLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVMGLISTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPGYSKIFGDWLCETAA
                     KDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPVVAIY
                     STFLQRAYDQVIHDVAIQKLPVMFAIDRAGIVGADGQTHQGAFDLSYLRCIPDMVIMT
                     PSDENECRQMLFTGYHYNDGPTAVRYPRGNAQGVALTPLEKLPIGKGLVKRHGEKLAI
                     LNFGTLMPEAAKVAEALNATLVDMRFVKPLDDTLILEMAAQHDALVTLEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEARAELGLDAAGIEAKIKAWLA"
     gene            complement(21888..22787)
                     /gene="ispA"
                     /locus_tag="OPY25_001453"
     CDS             complement(21888..22787)
                     /gene="ispA"
                     /locus_tag="OPY25_001453"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HCS0927100.1"
                     /translation="MDFTQQLQACVTQANQALSRFIAPLPFQNTPVVEAMQYGALLGG
                     KRLRPFLVYATGQMFGVSTATLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     IKFGEANAILAGDALQTLAFTIISDAPMPEVADRDRIAMIAELANASGIAGMCGGQAL
                     DLAAEGQRITLDALERIHRHKTGALIRAAVRLGALSAGDKGRNTLPILDRYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARNKARDLIEDARQSLHQ
                     LAAQSLDTSALEALANYIIQRDK"
     gene            complement(22788..23030)
                     /gene="xseB"
                     /locus_tag="OPY25_001454"
     CDS             complement(22788..23030)
                     /gene="xseB"
                     /locus_tag="OPY25_001454"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCS0927101.1"
                     /translation="MPKKNEAPASFETALSELEHIVTRLESGDLPLEDALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEEASPEPFIADNE"
     gene            23240..24688
                     /gene="thiI"
                     /locus_tag="OPY25_001455"
     CDS             23240..24688
                     /gene="thiI"
                     /locus_tag="OPY25_001455"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCS0927102.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALAQYREQL
                     EGKTFCVRVKRRGKHEFSSIEVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSSVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKVDDGQMGVVLKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAIKAKIEAEEENFDFSILDKVVEEANNVDIREIAQQTQ
                     QEVVEVETVSGFGANDVILDIRSVDEQDDKPLKVEGVDVVSLPFYKLSTKFGDLDQSK
                     TWLLWCERGVMSRLQALYLREQGFANVKVYRP"
     gene            complement(24738..25529)
                     /gene="phnV"
                     /locus_tag="OPY25_001456"
     CDS             complement(24738..25529)
                     /gene="phnV"
                     /locus_tag="OPY25_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transport system,
                     membrane component PhnV"
                     /protein_id="HCS0927103.1"
                     /translation="MLIWSPKGRAAAGVVASVLFIVFFFLPLAVILMSSLSQRWNGIL
                     PSGFTLNHFVNALHGAAWDALLASLTIGFCASLFALLCGVWAALALRQYGVKTQKWLS
                     MVFYLPSAIPSVSVGLGILVAFSQGPLQMNGTLWIVLTAHFVLISAFTFSNVSTGLAR
                     ISADIENVASSLGASPWYRLRHVTLPLLMPWMVSELALSLSLSMGELGATVMIYPPGW
                     TTLPVAIFSLTDRGNIADGAALTIVLVAITLLLMMKLERIAKRLG"
     gene            complement(25523..26392)
                     /gene="phnU"
                     /locus_tag="OPY25_001457"
     CDS             complement(25523..26392)
                     /gene="phnU"
                     /locus_tag="OPY25_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transporter permease
                     subunit"
                     /protein_id="HCS0927104.1"
                     /translation="MSLILPLEKPALNLRPLLWLLLPLLALATLFFWPLSLIVEQALR
                     GANGEIGLETFRQVVDSKRFVGALLNTLQIAFFATAGCLLLGSVMSLILVFIPFPGSE
                     LIGRVVDTFIALPTFLITLAFTFIYGSAGLLNGALMSLFAFELPPVDFLYSMQGVILA
                     EITVFTPLVMRPLMAALRQIDKSQLEAASILGAHPLRVIGQVIFPAALPALMASGSLC
                     LLLTTNEFGIVLFIGAKGVNTLPMMVYSKAILESDYTVACMIALINIVLSLGLFSLYR
                     LAASRTGVRSQPC"
     gene            complement(26395..27504)
                     /gene="phnT"
                     /locus_tag="OPY25_001458"
     CDS             complement(26395..27504)
                     /gene="phnT"
                     /locus_tag="OPY25_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transport system
                     ATP-binding subunit PhnT"
                     /protein_id="HCS0927105.1"
                     /translation="MLMKTTAVHAPASQGTSGIVLDSLRVAYHGNVVLKPLSLTIEPG
                     EVLALIGPSGSGKTTVLRAVAGFVQPAGGRILIGDTDVTHLPPYKRGLAMVVQNYALF
                     PHLKVEDNVAFGLRAQKQPKALINERVTQALKTVGMSDYATRYPHQLSGGQQQRVAIA
                     RAIAVRPRVLLLDEPLSALDAQIRHNMVEEIARLHRELPELTILYVTHDQTEALTLAD
                     KIGIMKDGSLIAHGETRALYHHPPNRFAAEFLGRANILSAIALGITEVPGLVDVSCGG
                     AVIRAFSQGSHHGYNKLLCIRPQHLSLTPRSAYSNRFNATLQSVHWQGDLTHLLCDVA
                     GETVRMVLTHVNPLPRVGDKLALWFEPDDAVLIEV"
     gene            complement(27510..28523)
                     /gene="phnS"
                     /locus_tag="OPY25_001459"
     CDS             complement(27510..28523)
                     /gene="phnS"
                     /locus_tag="OPY25_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HCS0927106.1"
                     /translation="MKLSRLALLSVFALASAPSWAESVVTVYSIDGLHDGDNSWYQVQ
                     FDAFTKATGITIRYVEGGGGVVVERLAKERTNPQADVLVTAPPFIQRAAAEKLLANFN
                     TDAASAIPDANNLYSPLVKNYLSFIYNSKLLKTAPASWQDLLDGKFKNKLQYSTPGQA
                     ADGTAVMLQAFHSFGSKDASFAYLGKLQANNVGPSASTGKLTALVNKGEIYVANGDLQ
                     MNLAQMERNPNVKIFWPANDKGERSALAIPYVIGLVQGAPQSENGKKLINFLLSKEAQ
                     TRVSELSWGMPVRSDVTPSDEHYKAATAALEGVQSWQPNWDDVAVSLSADISRWHKVT
                     ESE"
     gene            complement(28721..29440)
                     /gene="phnR"
                     /locus_tag="OPY25_001460"
     CDS             complement(28721..29440)
                     /gene="phnR"
                     /locus_tag="OPY25_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate utilization transcriptional
                     regulator PhnR"
                     /protein_id="HCS0927107.1"
                     /translation="MKSIPGDIPQYLLIKAQLQARIQSGALKSGDKLPSERELCAIFN
                     TTRITIRESLAQLESSGLIWRADRRGWFVTPERLWLDPTQNTNFHKLCREQGREPKTA
                     LLSGVLTTVPVEVMEPLQLQPFDQIYLLTRLRYADGRAVCYCENHCLPARVPELLQYD
                     LNGSLTEVYESHYNLVYTSMHLSFYPTAMPAQAAQALGVMEGRPALLLRRLNYDQHGR
                     VLDLDIEYWRHDSLRIEVDTH"
     gene            29580..30683
                     /gene="phnW"
                     /locus_tag="OPY25_001461"
     CDS             29580..30683
                     /gene="phnW"
                     /locus_tag="OPY25_001461"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCS0927108.1"
                     /translation="MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNIGVVEQIR
                     QQLTALATASEGYTSVLLQGSGSYAVEAVLGSALGPQDKVLIVSNGAYGARMVEMAGL
                     MGIAHHAYDCGEVARPNVQAIDAILNADPTISHIAMVHSETTTGMLNPIDEVGALAHR
                     YGKTYIVDAMSSFGGIPMDIAALHIDYLISSANKCIQGVPGFAFVIAREQKLAACKGR
                     SRSLSLDLYAQWRCMEDNHGKWRFTSPTHTVLAFAQALKELAKEGGVAARHQRYQQNQ
                     RSLVAGMRALGFNTLLDDELHSPIITAFYSPEDPQYRFSEFYRRLKEQGFVIYPGKVS
                     QSDCFRIGNIGEVYAADITALLTAIRTAMYWTK"
     gene            30693..31502
                     /locus_tag="OPY25_001462"
     CDS             30693..31502
                     /locus_tag="OPY25_001462"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCS0927109.1"
                     /translation="MNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEA
                     RVPMGLGKWQHIEALGKLPTVDARWQAKFGRAMSAADIDAIYAAFMPLQIAKVVDFSS
                     PIAGVIDTIATLRAEGIKIGSCSGYPRAVMERLVPAAAEHGYRPDHWVATDDLVAGGR
                     PGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAY
                     QTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPEVIAHINARLAQGERP"
     gene            complement(31599..32189)
                     /gene="yajL"
                     /locus_tag="OPY25_001463"
     CDS             complement(31599..32189)
                     /gene="yajL"
                     /locus_tag="OPY25_001463"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HCS0927110.1"
                     /translation="MSAQALVCLAPGSEETEAVTTIDLLVRGGIHVTTASVASDGNLT
                     IVCSRGVKLLADAPLVEVADGDYDIIVLPGGIKGAECFRDSPLLVETVKQFHRSGRIV
                     AAICAAAATVLVPHDIFPIGNMTGFPALKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(32152..33063)
                     /gene="panE"
                     /locus_tag="OPY25_001464"
     CDS             complement(32152..33063)
                     /gene="panE"
                     /locus_tag="OPY25_001464"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCS0927111.1"
                     /translation="MKITVLGCGALGQLWLSALCKHGHDVQGWLRVPQPYCSVNLIDT
                     DGSFFNESLTANDPDFLAKSELLLVTLKAWQVSDAVRTLASTLPVTSPILLIHNGMGT
                     IEELQSIQQPMLMGTITHAARRDGNIIIHVANGTTHIGPAREQDGDYSYLAEILQGVL
                     PDVAWHNNIRAEMWRKLAVNCVINPLTALWNCPNGELRHHTDEINAICEEVAAVIERE
                     GYHTSADDLCYYVEQVIDSTAENISSMLQDVRAMRHTEIDYITGYLLKRARVHGLAVP
                     ENSRLFEMVKRKESEYERSGTGMPRPW"
     gene            33189..33680
                     /locus_tag="OPY25_001465"
     CDS             33189..33680
                     /locus_tag="OPY25_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCS0927112.1"
                     /translation="MPSFDIVSEVDLQEARNGVDNAVREVESRFDFRGVEATIELNDA
                     NKTIKVLSESDFQVNQLLDILRAKLLKRGIEGASLDVPDEFVHSGKTWYVEAKLKQGI
                     ESAVQKKIVKLIKDSKLKVQAQIQGEEIRVTGKSRDDLQSVMALVRGDDLGQPFQFKN
                     FRD"
     gene            complement(33727..35091)
                     /locus_tag="OPY25_001466"
     CDS             complement(33727..35091)
                     /locus_tag="OPY25_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016507029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0927113.1"
                     /translation="MNDYKMTPGELRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLAQAIFQIPFGLLSDRIGRKPLIVGGLAVFVAGSVIAALSHSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIVTH
                     SLGLNALFWMIAALATLGILLTIWVVPNSTNHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMVIAFAAVVPFIIYAEVKRR
                     MKQVFLFCVGLIIVAEIVLWGAGQHFWELVIGVQLFFLAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVALGGSLGGWIDGTFDGQTVFLAGAVLAMVWLAVASTMKEPP
                     YVSSLRVEIPADIVADDRLKQRLLAMKGVSEALIVAEEHSAYVKIDSKVTNRFEVEQL
                     ISKG"
     gene            complement(35322..35452)
                     /locus_tag="OPY25_001467"
                     /pseudo
     CDS             complement(35322..35452)
                     /locus_tag="OPY25_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491235.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            35627..37136
                     /locus_tag="OPY25_001468"
                     /pseudo
     CDS             35627..37136
                     /locus_tag="OPY25_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
     gene            37148..37411
                     /locus_tag="OPY25_001469"
     CDS             37148..37411
                     /locus_tag="OPY25_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HCS0927114.1"
                     /translation="MIKRKWNLLLLLGFSFASVCQAGDDIDALYSRIAQKDVQALNEL
                     KALAKDNNAQALAELGFIYEYGVAVPKDTIQAIKYYEQACHVE"
     gene            37463..38617
                     /locus_tag="OPY25_001470"
     CDS             37463..38617
                     /locus_tag="OPY25_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001150187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HCS0927115.1"
                     /translation="MQDDVLAKELADKTSKADIDTDAQTVTRLIADEIDTAKQAAESD
                     ITQRSRFIETLRQYAGGGSAMAARITRLGYSKADILHLAELWAQERDPELNFIVGSLY
                     DSGFVEVDDKEARSLQWFRKAAELGQADAQNILGYFYLNGKRGIKRDLQKGGQWYELA
                     AAQGNVDALINLGEIYYSGTRVPLDYARAFEFFERAAKMGKSRALNYLAWMYTNGQFV
                     DTDCRKAAELFAQGRTSFADDPHFQVTCEKDRQARAEAVAMREKNLPKLTFNRDRVFG
                     ASQGSGYACELEFVVKTDRVSSIENLRVSLALKNKAGAMSQQVIAFEPFGLNMQNRNL
                     QGYKSDTLRESTLQPIYQPEFCDVDSYSVTAVTGIVNGKEMDILKAGIFI"
     gene            complement(38665..39555)
                     /gene="cyoE"
                     /locus_tag="OPY25_001471"
     CDS             complement(38665..39555)
                     /gene="cyoE"
                     /locus_tag="OPY25_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HCS0927116.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPGVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGDFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVIKGISVAKNHITLYIIAFAV
                     ATLMLTLGGYAGYKYLVVAAAVSVWWLGMALRGYKVEDDKVWARKLFGFSIIAITALS
                     IMMSVDFMVPNSQNLLTYVW"
     gene            complement(39567..39896)
                     /locus_tag="OPY25_001472"
     CDS             complement(39567..39896)
                     /locus_tag="OPY25_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HCS0927117.1"
                     /translation="MSHSTESGGASHGSVKTYMTGFILSVILTVIPFWMVMTGAASPA
                     VILGSILAMAVVQILVHLVCFLHMNTKSDEGWNMTAFIFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(39896..40510)
                     /locus_tag="OPY25_001473"
     CDS             complement(39896..40510)
                     /locus_tag="OPY25_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HCS0927118.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGQNKIFGFWVYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMHKNNKSQVISWL
                     ALTFLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQVARRGLTSTNRTRIMCLSLFWHFLDVIWICVFTVVYLMGAM"
     gene            complement(40500..42491)
                     /gene="cyoB"
                     /locus_tag="OPY25_001474"
     CDS             complement(40500..42491)
                     /gene="cyoB"
                     /locus_tag="OPY25_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HCS0927119.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAAIIVGGLAILAAITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNLSL
                     GVGEFAQTGWLAYPPLSGIEYSPSVGVDYWIWALQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMMWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYVLGFMGMTRRLSQQIDPQFHTMLMVAAAGAALIALG
                     ILCQLIQIFVSIRDRDQNRDLTGDPWGGRTLEWSTSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYQQPGQYEEIHMPKNSGAGIVIAAFATVFGFAMIWHIWWLAIVGFAGMIIS
                     WIVKSFDEDVDYYVPVPEVEKLENQHFDEITKAGLKNGN"
     gene            complement(42502..43458)
                     /gene="cyoA"
                     /locus_tag="OPY25_001475"
     CDS             complement(42502..43458)
                     /gene="cyoA"
                     /locus_tag="OPY25_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HCS0927120.1"
                     /translation="MRLRKYNKSLGWLSLIAGTALLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATKDRAEFDQWVAKAKQSPNTMNDMAAFEKVAMPSEYNKVEYFSSVKPDLFKD
                     VINKFMGHGKSMDMTQPEGEHSSHEGMEGMDMSHAESANSKG"
BASE COUNT        10157 a        11340 c        12145 g        10080 t
ORIGIN      
        1 tgttgatagg tcagaaattg atggaaagca ataataagct aaagcgtggg ctgagcaccc
       61 ggcacattcg ctttatggca ttaggttcgg caatcggcac cggcctgttt tacggctcgg
      121 cggacgccat caaaatggcg gggccgagcg tgctgttggc ctatattatt ggcggggtcg
      181 cggcatatat cattatgcgc gcattggggg aaatgtccgt tcacaaccct gccgccagct
      241 cattttcgcg ctatgcgcag gaaaacctcg gcccgcttgc gggctacatt accggctgga
      301 cctactgttt tgagatcctg atcgtcgcca ttgctgacgt gaccgcgttc ggcatttaca
      361 tgggggtctg gttccccgcc gtgccgcact ggatttgggt gcttagcgtg gtgctgatca
      421 tttgcgccat caacctgatg agcgtcaaga tgttcggcga gctggagttt tggttctcct
      481 tcttcaaagt cgccaccatt attatcatga ttgtcgcggg tatcggcatc attgtgtggg
      541 gaattggcaa cggcgggcag ccgactggca ttcataacct gtggagcaac ggcggcttct
      601 tcagcaatgg ctggctggga atgatcatgt cgctgcaaat ggtgatgttc gcttacggcg
      661 ggattgagat tatcggtatc accgccgggg aagcgaaaga cccggagaaa tccattccgc
      721 gcgccattaa ctcagtaccg atgcgtatcc tggtatttta tgtcggcacg ctgttcgtca
      781 ttatgtctat ctatccgtgg aatcaggtcg gcacaaacgg cagcccattt gtgctgacgt
      841 tccagcatat ggggattacc tttgccgcca gcattctgaa ctttgtggta ttgaccgcct
      901 cgctttccgc tatcaactcc gatgtgtttg gcgtaggccg tatgctgcat ggtatggcgg
      961 agcaggggag cgcgccgaaa gtctttgcca aaacgtcacg ccgtggtatt ccgtgggtca
     1021 ctgtgctggt gatgacgatt gcgctgctgt ttgcggttta cctgaactac atcatgccgg
     1081 aaaacgtctt cctggtgatt gcctcgctgg tgacgtttgc gacggtatgg gtatggatta
     1141 tgatcctgct gtcgcaaatc gccttccgtc gtcgtttacc gccggaagag gtaaaagcgc
     1201 tgaagtttaa ggtgccgggc ggtgtcgtaa cgacgatagc gggtctgatt ttcctggtct
     1261 tcattattgc gcttatcggc taccatccga atacccgcat ctcactgtat gtgggcttcg
     1321 cctggatagt tctgctgttg attggctgga tatttaaacg ccgtcgcgac cgtcaattgg
     1381 cgcaggcgta gtcgtttttc tctgccttat ccggtctgca ggcaacggca ggccggataa
     1441 gcggagccgt ttctcctcct ggagtctcct cccctaataa acccccggat gatgagttat
     1501 cctttaaatc tctgtggcaa ggtggcccca tttttagtag aggggatacg agatgttgaa
     1561 tgcctggcac ttaccggttg ccccgtttgt taagcaacat aacgataaat taaccattac
     1621 gctgtggctg agcggagaaa atccgccgtc tcgcgtgacg ttgcgctcag aattcgataa
     1681 cgaagaaatc tcactggcga tgcgcaaaca gcgccgccag ccgcagccgg gcgtgacggc
     1741 gtggcgagcg acgctcaata tcgcgttagg gcagccccgt cgccgttaca gctttaaatt
     1801 gctttggcat gaccgccagc gatggtttac gccgcaggga tttagctgct ttccacccgc
     1861 gcgtctggaa caatttgcgg ttgatgtgcc ggatagcggc ccgcagtggg tcgccgatca
     1921 aattttttat cagatcttcc cggatcgttt tgcccgcagc gcgacgcgtg aagccgatca
     1981 ggaccgagtg tattaccatc atgccgcggg tcaggagatt gtgctgcgcg actgggacga
     2041 tcctttaacc ccccaggcgg gcggttccac cttttacggc ggctgtctga atggcatttg
     2101 tgagaagctg ccgtatctga aaaaactggg cgtcacagcg ctatatctga atccggtatt
     2161 taccgcgccg agcgtccata agtacgacac ggaagattat cgccatgtcg atccgcaatt
     2221 tggcggcgat cgggcgctgc tacgcctgcg gcgtgaaacg caagcacagg gcatgaggct
     2281 ggtgctggat ggcgtgttta accatagcgg cgactcgcat gcgtggtttg acaggcataa
     2341 ccgcagcact ggcggcgcgt gccatcaccc ggactcgccg tggcgcgact ggtactcctt
     2401 ttcaccacaa ggcgtggcgc tggactggct gggttatccg agcctgccga aactcgatta
     2461 tcaatcagaa acgctggtgg atgagatcta tcgcggtgag gacagtatcg ttcgtcactg
     2521 gctaaaggca ccgtggaata tggacggctg gcggctggat gtcgtacata tgctgggcga
     2581 ggcgggcggg gcgcgccaca atttgcagca cgtcgccggc attacccggg cggcaaaaga
     2641 ggcgcagcct gaagcctata ttgtggggga acatttcagc gatgcgcggc agtggctaca
     2701 ggccgatgcg gaagatgccg ccatgaatta tcgcggcttc accttcccgc tgtggggatt
     2761 tctcgccaat actgatatcg cttacgaacc acagcatatt gatgcccgga cctgtatcgc
     2821 gtggatggat aactaccgcg ccggattatc gcaccagcag caactgcgca tgtttaatca
     2881 actcgacagc catgatactg cgcgctttaa aaccctgctg ggtaaagacg cggcgcgcct
     2941 gccgctggcg gtggtctggc tgtttacctg gcccggcgtg ccatgtattt attacggcga
     3001 tgaagtcggc gtggacggcg caaatgaccc catgtgccgc aaaccgttcc catgggatga
     3061 acgcaagcag gacggcaact tgctggcgct gtaccagcgt atggcgaaac tgcgccagag
     3121 cagtctggcg ctgcgtcgtg gcggatgcca ggcgctgtat gccgaaggtg acgtagtggt
     3181 attcgtgcga gtttatcagc agcagcgggc gctggtggcg attaaccggg gcgaggcctg
     3241 tgaagtggcg ctggaagcgt tgccgttgct gaacgtggcc ggatggcaat gtaaaacggg
     3301 aagcggtgac atccgcgagg gaagacttag tttacccgcg atttccgcga cggtatggat
     3361 gaatcgttga ggcgaggtgg ttcataatac ctcacgcata aaaaaggctc gcattcgcga
     3421 gccttttatc aatgcactga cttacaggct ggaaatattc tcagccaggt atttagccac
     3481 gccgtccgga gaggcgttca tgccttcttt gcctttttcc cactgcgccg ggcagacatc
     3541 gccgtgctct tcgtggaact gcagcgcgtc gaccatacgc agcatttcgt cgatgttacg
     3601 acccagcggc agatcgttta cgacctggtg gcgaacaata ccgtttgcgt caatcaggaa
     3661 agagccgcgc agcgcaacgc cttcgtccgg atgttcgata ccgtaagctt tctgaatttc
     3721 acgcttcacg tcagcgacca ttgcgtattt caccgggcca atgccgcctt tatcgacagg
     3781 ggtgttacgc catgcgttgt ggacgaactc agagtcgaaa gaaacgccga ccacttcaac
     3841 gccgcgcttc tggaattctt cataacgttt atcgaaggcg atcagctcag acgggcaaac
     3901 aaaagtgaag tccatcggcc agaagaacag aacggtcgtt ttaccattgg tgtgctgttt
     3961 gaagttgaat ttatcaacaa tctcaccgct acccagtacc gccgcagcgg tgaaatccgg
     4021 ggcctgacga gtaaccagta ccataataat tctcctgcaa tattaagggt tttagaacgc
     4081 aacgcgggca gtatagggag ggcgaagcga caaaacaatg cggtcttgac aatcaatgag
     4141 acagcttttg cctatcgatc gggtcattat aaatcgtaat gatgactcct ttatgacagc
     4201 gaacgatctt tctgccaacg gcggatctga cgcacgccct cgctatcagg ccgtcacagc
     4261 gctttgcggg cggcctgtgc catcatacgc ggataaaaat gccagaagcg ctcttctaac
     4321 gcgtcgtagt gcgcgtccag atcgtaccag gaatcacgca aggcatccag ccggggacgg
     4381 cgattcgcca tgccattcag cacgttttga atgaaatcca tatcgcgata ccgctctaac
     4441 catttttctg accaaagata atcattcagg ttgacaaagc gcggcgggga gtcgggcaga
     4501 atcgtcgcga cctgcgcatg ggcgtagccg acaaacgcct gaagtggaaa atcgggagag
     4561 atttgcgtcc agtggcgcga taaaaaatga tcccacatga cgtccagcgt aatgggcgcc
     4621 acgcgccgcg tttcatggcg gaaccactct cgcgcctcac gaacttccgg caggttgtcg
     4681 gtcatgacgt caatacgccg atgcatataa ataccctcta ccacgtcagg aggataatgc
     4741 gttgccgggt taccgcggac aaaatcggcc agcagattac cggaaagcga gctgtcggca
     4801 aggtgcgcca gatgcaggtg agcaagaaaa ttcattattg attctctgtc caaaaagcgg
     4861 gtaacggttg cagcgggaac gccccggcac tagactaccc gcctcttatt ttagtctgag
     4921 tcagagtcat gcgcgttacc gatttttcct ttgaactacc cgaatccttg attgcccact
     4981 acccacagcc ggaacgcagt cgctgccgtt tgctgtcatt agaggggccg acgggcgcgc
     5041 tgacgcacgg tactttcacc gatctgctcg ataagctcaa ccctggcgat ttgctggtct
     5101 tcaataatac ccgcgtgatc ccggcgcgcc tgtttggccg taaagccagc ggcggcaaga
     5161 tagaagtgct ggtcgaacgt atgctcgatg ataaacgcat cctggcgcat attcgcgctt
     5221 ctaaagcgcc aaaaccgggc acggaactgc tactgggcga tgacgaaagt attcacgcga
     5281 ccatgaccgc gcgtcacggc gctctgtttg aagttgagtt taatgacccg cgtccggtgc
     5341 tggatattct caacgccatc ggccatatgc cgttgccgcc gtatatcgac cgtccggacg
     5401 aggacgccga ccgcgaactg tatcagacgg tttacagtga aaaaccgggc gccgtcgccg
     5461 cgccgaccgc ggggctgcac tttgatgagc cgctgctggc ggcgcttcgt gagaaaggtg
     5521 tcgaaatggc gtttgttacg ctacacgtcg gcgcgggcac tttccagcca gtgcgtgtcg
     5581 ataccattga agatcacatc atgcactccg aatatgctga ggtgccgcaa gaggtggtcg
     5641 acgcggtgct ggcggcgaaa gcgcgcggca accgggttat cgccgtcggc acgacctcgg
     5701 tacgctcact ggagagcgcg gcgcaggcgg caaaaagcga tttgatagag ccattcttcg
     5761 gcgatacgca aatctttatt tatccaggtt atcaatacaa agtgattgat gcgctgatca
     5821 ccaacttcca tctgccggaa tcgacgttga ttatgctggt ttccgcattt gccggttatc
     5881 aacacaccat gaatgcctat aagactgcgg tagaacaaaa atatcgcttt tttagctacg
     5941 gggacgcgat gtttatcacg tgcaatccgc aggctatttc tgagcgtccg taagaaggct
     6001 atctcacttg ccattttgac gccgggcagt gctcgccatc ctcacgtact gcgtgtacgc
     6061 tccggtggtt gtgcgctggc cgactccaaa ctggctgcgc cgatgacgcc ttcgggaatt
     6121 tattagctat ggaatcattc cgtagcgagt cgttaaacgt cggactgttt ttctgacgca
     6181 ggagtgataa tgaaatttga gttagatacc accgatggtc gcgcgcgtcg cggtcgtctg
     6241 gtgtttgatc gtggcgtagt ggaaacgcct gcttttatgc ctgtgggtac ttacggtacg
     6301 gtaaaaggca tgacgccgga agaagtggaa gcgaccggcg cgcagattat tctcggcaac
     6361 actttccacc tgtggctgcg cccgggtcag gaaatcatga agctgcacgg cgacctgcac
     6421 gatttcatgc agtggaaagg gccgattctc accgattccg gcggcttcca ggtcttcagc
     6481 ctcggcgata ttcgtaagat taccgagcaa ggcgtgcact tccgtaaccc gatcaacggc
     6541 gatccgattt tcctcgatcc ggaaaagtcg atggagatcc agtacgatct cggttccgat
     6601 atcgtgatga tctttgatga atgtacgccg tacccggcag actgggacta tgctaaacgc
     6661 tcgatggaga tgtcgttgcg ttgggcgaag cgtagccgcg accgttttga tagccttggc
     6721 aataagaatg cgctttttgg catcattcag ggcagcgttt acgaagattt acgcgatatc
     6781 tcggtgaaag gtctggtaga gattggcttt gatggctacg ctgtcggcgg tttggctgtc
     6841 ggtgagccga aagcagatat gcaccgcatt ctggagcacg tttgcccgca gatcccggct
     6901 gacaaaccgc gttacctgat gggcgtgggt aaaccggaag atctggtgga aggggtgcgt
     6961 cgcggtattg atatgtttga ctgtgtcatg ccaacgcgaa atgcccgtaa tggtcatctg
     7021 tttgtgaccg acggcgtggt gaagattcgt aatgcaaagc ataaaagcga catcagcccg
     7081 cttgacgccg agtgcgattg ctacacctgt cgcaattatt cacgcgctta cttgcatcat
     7141 ctcgaccgtt gcaacgaaat attaggtgcg cgtctcaata ccattcataa cttgcgttac
     7201 taccagcgtt tgatggcggg tttacgcaag gctattgaag agggtaaatt agagagcttc
     7261 gtaaccgagt tttaccaacg tcaggggcga cccgttccac ctttgaacgt tgattaattt
     7321 taataatgag ggaatttgaa tgagcttttt tatttctgat gcggtagcgg caacaggtgc
     7381 tccggcgcag ggcagcccga tgtctctgat tttaatgctg gtggtgtttg gtctgatttt
     7441 ctatttcatg atcctgcgcc cgcagcagaa gcgcaccaaa gagcacaaaa agctgatgga
     7501 ctccattgcg aaaggtgatg aagttctgac gaatggcggt ctggttggtc gagtgaccaa
     7561 agtagcggaa gccggctaca ttgccatcgc gctgaatgac accacggaag tggttatcaa
     7621 acgtgacttc gtagctgccg ttctgccgaa aggcaccatg aaggcgctgt aatatttcgt
     7681 tttcccaaag ggaactgccg tgttaaaccg ttatcctttg tggaagtaca tcatgctggt
     7741 cgtcgtgatt atcgtcggcc tgctttacgc acttcccaac ctgtatggtg aggatccggc
     7801 tgttcaaatc actggcgtgc gcggcgtcgc cgccagtgag caaacgctga tccaggtcca
     7861 gaaaacgtta caagaagaaa aaattcccgc taagtctgtg gcactggaag agggcgctat
     7921 tcttgcgcgc ttcgacacca ccgataccca gctacgcgcc cgtgaagcgc tgatgagcgt
     7981 gctgggggat aaatatgtcg tggcgcttaa ccttgcgccg gctacgccgc gctggttggc
     8041 ggctattcac gccgatccga tgaagctcgg tcttgatctg cgcggcggcg ttcacttcct
     8101 gatggaagtg gatatggata ccgcgttagg taaactccag gaacaaaata tcgatagcct
     8161 gcgcagcgat ctgcgtgaaa aaggcattcc ttataccacc gttcgtaaag aaaataatta
     8221 tgggctgagc atcacgttcc gtgacagcaa agcgcgtgat gaggcgatcg cctatctgac
     8281 gccgcgtcat cgtgacctgg tgatttccag ccagagcggc aatcaacttc gcgcggtaat
     8341 gaccgatgcg cgcctgagcg aagcgcgtga atacgccgtt cagcagaaca ttaatattct
     8401 gcgtaaccgt gttaaccaac tgggcgtcgc ggagcctgtc gtacaacgcc agggcgcaga
     8461 ccgtattgtg gttgagctgc cgggtatcca ggataccgct cgcgcgaaag aaattctcgg
     8521 cgcgaccgcg acgctggaat tccgtctggt gaataccaac gttgaccagg ccgccgctgc
     8581 tgccgggcgc gtaccgggcg attccgaagt gaaacagacc cgcgaaggtc agccggtggt
     8641 attgtacaaa cgcgtgatcc tcaccggcga ccatatcacc gactcgacgt ccagccagga
     8701 tgaatataac caaccgcagg ttaacatctc gctggatagc gcaggcggca atatcatgtc
     8761 taacttcact aaggacaata tcggcaaacc gatggcgacc ctgtttgtgg agtataaaga
     8821 cagcggtaag aaagacgcta acggtcgcgc cgtactggtg aaacaggaag aggtgattaa
     8881 cattgccaac atccagtctc ggctgggtaa cagcttccgt attaccggta tcagcaaccc
     8941 gaacgaagcg cgtcagctct cgttgttgct gcgtgcgggt gccctgattg cgccgattca
     9001 gatcgttgaa gagcgcacca ttggcccgac tctgggtatg cagaacatca agcagggcct
     9061 ggaagcctgt ctggccggtc tggtggtctc catcctgttc atgatcttct tctataagaa
     9121 gtttggtctg attgcgacca gcgcgttagt ggctaacctg gtgttgattg tcggtatcat
     9181 gtcgctgttg ccgggggcaa cgctcagtat gccggggatt gcgggtatcg tgttaaccct
     9241 tgcggtggcg gtcgacgcca acgttctgat taacgaacgt atcaaagaag agttgagtaa
     9301 tggccgcacg gtacagcagg cgataaacga aggctatgcc ggcgcgttca gttccatctt
     9361 cgatgcgaac atcacgacgc tgattaaagt catcattctg tatgctgtcg gtaccggggc
     9421 aattaaaggg ttcgcgatta cgaccggtat cggtgtggcg acgtcgatgt ttaccgcgat
     9481 tatcggtacg cgtgctatcg taaacctgct atatggcggc aagcgcgtca ctaagctgtc
     9541 aatctgagga gtgcgatgtg gcacaggaat acactgttga acaactaaac cacggccgta
     9601 aagtctatga ctttatgcgc tgggacttct gggcattcgg catctccggg ctgttgctga
     9661 tcgcggccat tgtcattatg ggcgtacgcg ggtttaactg ggggctggat ttcaccggtg
     9721 gtacggtaat tgaaatcacg ctggaaaaac cggctgaaat ggacgtgatg cgcgaagcgc
     9781 tgcaaaaagc gggctatgaa gagccgcagt tgcagaactt tggcagcagt cacgacatta
     9841 tggtgcgtat gccgccaacc gaaggtgaaa ccggcggtca ggtactgggt agcaaagtgg
     9901 tgacgatcat taatgaagcc accaaccaga acgcggccgt gaagcgtatt gaattcgtgg
     9961 ggccaagcgt gggcgccgat ctggcgcaaa ccggcgccat ggcgctgctg gtggcgttga
    10021 tctctatcct cgtttatgtc ggtttccgct ttgagtggcg actggcggca ggggtggtca
    10081 tcgcgctggc gcacgacgtg atcattacgc tggggatact gtcgcttttc catattgaga
    10141 ttgacctgac cattgtggca tcgttgatgt cggtgatcgg ttactcgctg aacgacagta
    10201 tcgtggtctc cgaccgtatt cgtgaaaact tccgcaaaat ccgtcgcggg acgccttacg
    10261 aaatctttaa cgtgtcgctg acccagacgc tacaccgtac gttgattacc tccggtacga
    10321 cgttagtggt aattctgatg ctgtacctct tcggcggtcc ggtactggaa ggcttctcgc
    10381 tgacgatgct gatcggtgtc tctattggta cggcatcttc tatctatgtc gcatcggcgc
    10441 tggcgctgaa actcggtatg aagcgcgagc atatgctgca gcagaaagtc gaaaaagaag
    10501 gggcggatca gccgtccatt ctgccgtaaa cacgtattta agtgttatct gaatcccggt
    10561 catgcgatcg ggatttttta tttatgtacc atgacgataa acattactga cagtatgctg
    10621 tcaggagccc tgtcatacac tcctcatgaa tttacccaca ctcgcaggag gatgtatgaa
    10681 aaacttgatt aactggtttg aaattccagt tactgatatg gcgcgtgcaa tcgcctttta
    10741 tgagcaagtg atgcagatat cgttacgtcg ggaaaccatg gatggggcgg acctggccgt
    10801 attcccgtat gctgaacccg gacccggcgg agcgctgata aagcaggatg atgtcgctcc
    10861 agttgcgcag ggagtcgtta tttatctgca taccgccgat ttgttagcct cgattgaacg
    10921 tgtcgtcctt gccggtggca agtgtgttct ggaacccatg gttcccggag atgacattgg
    10981 aaccatcgcg ttgtttattg acagcgaagg taaccgaata ggtttacatc aacctgcgtg
    11041 atatttgcta aatgtagaga gtcaatatga ccagacgcgc tgaccgtttg tttcagatcg
    11101 tgcaaatttt gcggggtaga cgactgacga cggcagcgct gttggcacag cggcttgcgg
    11161 tttctgaacg gacgatttat cgcgatattc gcgatctgtc gttatccggt gtgcctgtcg
    11221 aaggtgaagc ggggagcgga taccgtttaa tggcgggttt tgatctgccg cccttgatgc
    11281 ttacccatcg tgaatcggaa gcactgatgg tggctatacg gttattgaaa acctggggtg
    11341 gcgattcgct atcgcgcgag cttgaatccg cccaggaaaa agtgttggct attttaccgg
    11401 aagagagccg tcgtaaagcg gagcagacac ggatttacgc tccggatttg ggtacatctc
    11461 cacattcgcg cagcgcgttt gatcttatcc atcaggctgt ttcggcgcag caggtgttgg
    11521 cgctacatta tcgtgatgaa gcggggcatc tctcttcgcg ggatatacaa cctctgggat
    11581 tgtttttctg gggagagcac tggctactgg ttgcctggtg tgagagacgg gaagactatc
    11641 ggtgttttcg cctcgatcgc tgtttacaaa ttactccgct taaccggcga tttcgtgaaa
    11701 caatcgaccg ttctttgcgt gattttttgc gtaaagtcga gcacgaaaaa atgccgtaag
    11761 atgtgatagc gatacctcca acgcttgtaa aacgggttga ttggtcatca gtttgcctga
    11821 aatagccttc cttacctgga tatataagtt gcacagaatc attgctaaaa gcccggcttc
    11881 gcgggaaact gcgcataacc ctttgtatta ttcaggtacc tgttaattat ggctatcatc
    11941 ccaaaaaact acgcgcgcct ggaaagcggc tatcgtgaaa aagcgctgaa gctgtttccg
    12001 tgggtgtgcg gacgttgttc ccgtgagttt gtgtattcaa atctgcgtga gctgacggtg
    12061 catcatatcg atcatgacca caccaataac ccggaagacg gcagtaactg ggagctattg
    12121 tgcctctact gccacgatca tgagcattct aaatataccg aagccgatca gtacggttcg
    12181 acggtcattg ccggggaaga tgcgcaaaaa gatgtcggcg aggcgactta taacccgttt
    12241 gccgatctga aagcgatgat gaacaaaaag aaataagcag actgctgaca aagctgttgg
    12301 tgctgttgaa tgttaggtta cgcttcgctc cactccaccc aacggaatcc gcaatataaa
    12361 tgaattattg gttttcgtag gtcggatgca atctgacatt ttttcagccc cggagtttgt
    12421 cgccagcccc aaacgtcctg taacgcatac attgtcactg gaattccgat cgcaaggttg
    12481 ggattttttt gtttttaagt cctgccgata ctggcgagca gagtagaatc agcggtaagc
    12541 cggggcaacc cggtgaggcg caatgttgcg ggggcttgat ccccggtggc cttgtcgctg
    12601 gaaagagaaa acccccgcac attgttcggt attcaccggc aacattacgg gggctaactt
    12661 gaccccagac aagttgagga tagccgcgaa ccgttgccat tgcaacaaag gcggcaatat
    12721 gacgctcaca gagttgagca ttactatctg gcacgatctg gcggcaccaa cgctggtcgg
    12781 gattgcgaca ggtctgtttt taggctggtg gcatcgccgg aagtaatgtg aagtgggcgc
    12841 gactcgccgc cgcatggcag catgcgcccg aaacgggcca gaggacgacc tctggctttt
    12901 ttgcaggttt agaagttgta acccacgacc aggtaaccgc cccagccggt agatttcgcg
    12961 ctgaaatcgc cgtcgcccca gttcagtttg gcgccattct gccactgtcc gccgttatgg
    13021 aagtaacgcg caacgaccga gtagtgccag tgatcgtagt tcagcgccag gatatggctg
    13081 gaagcgatgg agttgctggt acggttcgga tcgtcgccta aatcagatcc ccagtcaaag
    13141 ttggtaaagc cgatatagct cagtttaccg ccccacagat cggtgatggg gacgaagtat
    13201 ttcactttga aacggtagcc gtcccattcg ttttcattgg acgcgccgta gttttgccac
    13261 tgatatttcg catacacgtt cagcgacaga cccatcggca ggccggtgtc gatatcggtc
    13321 cccagaccca tataccatgt gctctggcgg ctggctttgt tatcgcccat atcgtagatg
    13381 tagttgttgg cgaaatacca ctctttaaac gggccaaagc tcaggtctgc gccggtcagc
    13441 ttatcaatcg agaaacgcgg ttcgatttcc atgaacagcg gagaaccgtc ggaccagata
    13501 cctttatcgt tgccgttacc ccaatcaaag gttttgggaa tatcgatata gccgtagaaa
    13561 tcaaaccagt cttttttggc aaatgcttca tattccagat agacgtcgtt gttcaatttc
    13621 ggcgagaaac gggtatggta gctgcctacc acgtttacgc tctggtgcca ccagtcggac
    13681 aaatactgcg gctgatcatt ttctgctgcg ttagcagtaa aagatgaggt gagcgccagc
    13741 gctgcgctga ctgcgagtaa agtttttttc atatgtatgc cactgtttga aatcccttgc
    13801 gggagtgaaa agaacgcaat ttgcgtttct aaatatttcg tgtttctgcg gagcctatta
    13861 taaaaatcat tgctcacaaa aatatgtctt gtttcacata tctatcattt acgtaatcga
    13921 ttgcgttcac gtttgcgcac tttaggcgcg gcgacagtac tatctttcat gaatattaac
    13981 aatccgtgtc ataaattacg gaaatgtcag aagggcaaca aaagttgcgc agaggatgtt
    14041 gcggagcgca caaaacgctc cgccagaacg tttattgatt aacaggctga atatcatgga
    14101 tgcgaatgaa gcctaactgc gccggtgtga tccccttcaa cggtaacgga atattgacat
    14161 cactgggcgc cagcaagctg gcgggcgcat ttaccagaag gctctgcgca ttcacctcct
    14221 gatagttctc cgtagtgccc tgaatttgcc cgtactctac ggtagcgctg aatgccggta
    14281 gcggatcgcg ggacttgccc tgaatgcgta acgttgcgtg agcgccgtca gcgacaggcg
    14341 taatttccag caatgtcata cgtagcgtac cgatctgact ctccagccgg gcaggcgtat
    14401 tggcgccagg caacaaatag acgccgcggg ttgaatccgc attcagctta ttttgttggg
    14461 taatttttac cgtttcctga ttcagttggg tcatctcttt attcagggtg ctaatgcttt
    14521 gatgcatctg gcgaacttcg ctctgcggcg cgcaggcggt caggctcaag agacttccca
    14581 ccaggagaat tcttaggtaa cgtcttgtca tgtcgatcat ttccttcgtg gtccgatagc
    14641 gtaatggtag tgcgctatac gcacaaaggc accgatcctt tatctcaaaa gcgctccgcc
    14701 tttgttgtcg cgccagttca gggtaaaata gcatttccta aatcatctgg tcaggacgcc
    14761 gtatgcattg cccattttgt ttcgccgtag ataccaaagt cattgactct cgtcttgtag
    14821 gcgagggctc gtccgtgcgc cgccgtcggc agtgtctggt gtgtaatgaa cgctttacga
    14881 cctttgaagt ggctgaactg gtcatgccgc gcgtgataaa aagcaacgat gtgcgcgaac
    14941 cctttaatga ggataagctg cgtagcggca tgttgagagc gctggaaaaa agacccgtca
    15001 gcgcagatga tgttgaaatg gcattgaacc atattaagtc acaattacgt gccactgggg
    15061 agcgtgaagt tcccagcaag atgattggca acctggtcat ggagcagctg aaaaaactcg
    15121 ataaagtcgc gtatattcgc tttgcctccg tctatcgcag tttcgaagat atcaaagact
    15181 ttggcgaaga aatcgctcgc ctacaggact aagccatgca ggatgagttt tacatggcgc
    15241 gagcgctcaa actggcgcag cgtggacgtt tcaccactca cccgaaccct aatgtcggct
    15301 gtgtcattgt taacaatggc gacatcgtcg gcgaaggtta tcaccatcgc gccggagagc
    15361 cgcacgccga ggtccatgcg ctgcggatgg cgggcgcaaa agccaaaggc gcaaccgcct
    15421 atgtcacgct tgaaccctgt agccatcatg ggcgaacgcc gccatgttgc gatgcgctga
    15481 ttgcggctgg cgtcgcgcgc gtggtcgccg cgatgcagga cccgaaccca caggtcgccg
    15541 ggcgcgggct gtatcgcctg caacaggcgg gtattgcggt cagccacggg ttaatgatga
    15601 gtgaagcgga ggcgctcaat aaaggcttcc tcaaacggat gcgtaccgga ttcccttatc
    15661 ttcagcttaa actgggtgcc tccgtggatg gacggacggc gatggccagc ggcgaaagcc
    15721 agtggatcac ctcgccgcag gcccggcgcg acgttcagcg cttgcgtgcg caaagccacg
    15781 ctattttaac cagtagcgcg acggtattgg ctgacgatcc ggccttgacg gtgcgttggg
    15841 cggagttaga cgcctctaca caggcgtctt acccgcagga aaatctgcgc cagccggtgc
    15901 gaattgttat cgacagccaa aaccgggtaa cgcctgcgca tcgtattgtg cagcagcctg
    15961 gcgaaacgtg gattgcgcgt acccaggaag atagccacgc gtggcccgat tcggttcgta
    16021 ctatcagcgt gccggcgcac aacggacatt tggatctggt tgtgctgatg atgcagttag
    16081 gcaggcagca gattaatagc atatgggttg aggccggacc gggactggcg ggcgcgttgc
    16141 tgcaagccgg gctggtggat gaactgattg tctatgtcgc gcctaaattg ttgggaaccc
    16201 aggcgcgggg attatgcgaa ttgccggggc ttgagaagct cgccgacgcg ccgcaattta
    16261 ccttcagcga aatacgtcat gtcggcccgg atgtttgcct gcatatggtg agcgcatgag
    16321 ttctcccgtc gaaaggggag cagcgctcaa attattatga taaaatccgc ccccctgcgg
    16381 ggccaaatga accctggaag agagaatatg aacattatta aagctaacgt tgcagcccct
    16441 gacgctcgtg tcgccatcac tattgcgcgt ttcaatcagt ttatcaacga cagcctgctg
    16501 gatggcgcgg ttgatgccct gacgcgtatt ggtcaggtaa aagatgataa tattaccgta
    16561 gtgtgggtgc ctggcgctta tgaactgccg ctggcgaccg aagcgctggc gaaaagcggt
    16621 aaatacgacg ccgtggttgc gctgggaacc gtgattcgcg gggggactgc gcactttgaa
    16681 tatgtggcag gcggcgccag caatggcctg gcaagcgttg cccaggacag cggcgtgcca
    16741 gtagcctttg gtgttctgac caccgagagt attgaacaag ccatcgaacg tgctggtaca
    16801 aaagccggta ataaaggcgc agaagctgcg ctgaccgcgc ttgaaatgat taatgtattg
    16861 aaagccatta aggcctgatt ttttgtaagg ggaattccgt gaaacctgct gctcgtcacc
    16921 gcgcccgtga gtgtgccgtc caggcgcttt actcctggca gttgtcccag aacgacatcg
    16981 ctgatgttga ataccagttc ctggcggaac aggacgtaaa agacgtcgac gttctctatt
    17041 tccgtgaact gctatccggg gtggcgacta acagcgcgta cctggatggt ttaatgaaac
    17101 cgtatctgtc ccgcctgctt gaagagctgg gacaggttga aaaagccgtg ctgcgtattg
    17161 cgttgtttga gctgtcaaaa cgcagcgatg tgccttataa agtggccatc aacgaagcga
    17221 ttgaactggc gaaaaccttt ggcgctgaag acagccacaa attcgtcaac ggcgtactgg
    17281 ataaagcagc tccggtgatt cgtcccaaca aaaagtgatt cacaggccgg aaagatagcg
    17341 ggcgatcgat acccgccgtc tccggccttt tctttttttc tgctgaggca taacgtatgg
    17401 catgtggcga gttttccctg attgcccgtt attttgaccg tgtaagaagc tctcgtcttg
    17461 atgttgaaac cggtattggc gacgattgcg cgctcctgaa tattcctgaa aagcagaccc
    17521 tggcgatcag taccgatacg ctggtggcgg gcaaccactt cctccctgat atcgatcctg
    17581 ccgatctggc ttataaagcg ttggcggtga atttaagcga tctggccgcg atgggggccg
    17641 acccggcctg gttaacgctg gcgttaacgc taccggaagt ggatgagccg tggctggagg
    17701 cttttagcga cagcctgttt gcgctattga attactacga tatgcagctc attggcggcg
    17761 acaccacgcg tggaccgctg tcgatgacgc tgggtatcca cggttatatc ccggcagggc
    17821 gcgcgctcaa gcgatctggc gcgaagccgg gcgactggat ttatgtcacc ggtacgccgg
    17881 gcgacagcgc tgccgggctg gcggttttgc aaaaccggct acaggtgtcg gaggagaccg
    17941 atgctcacta tttaattcaa cggcatttac gcccgacgcc gcgtatttta cacggccagg
    18001 cgctgcgtga catcgccagc gcggctatcg atctttccga tggtctgatt tccgatctgg
    18061 ggcatatcgt caaggccagc ggctgtgggg caagagtgga tgttgatgcg ttgccaaaat
    18121 ccgatgcgat gatgcgccat gttgatgacg ggcaggagct gcgttgggcg ctttccggcg
    18181 gcgaagacta tgagttgtgc tttacggtgc cggaactgaa ccgtggcgcg ctggatgtcg
    18241 ccattggtca actgggtgtt ccctttacct gcataggcca aatgagcgca gatattgaag
    18301 ggctgaattt tgtacgtgac ggaatgcctg tcaccttcga ctggaaagga tatgaccatt
    18361 ttgccacgcc ataaagatgt tgcgaaaagt cgcctgaatt tgcgcaatcc gtggcatctg
    18421 ctcgctaccg gctttggcag cgggctgagc cccgtggtgc cgggtacgat gggctctctg
    18481 gcggcgatcc ccttctggta tctgatgacg tttctgccgt ggcagcttta ttcgctggtc
    18541 gtgatgtttg gaatctgcat tggcgtttat ctttgccatc agacggcgaa agatatgggc
    18601 gtacacgacc acggcagtat tgtctgggat gaatttatcg gtatgtggat aacgctaatg
    18661 gcgttgccga cgacggactg gcaatgggtg gctgccgggt tcgttatttt ccgcattcta
    18721 gatatgtgga aaccctggcc gatccgttgg tttgatcgca acgtgcacgg cggcatgggg
    18781 ataatgatcg atgatatcgt cgccggggtg atatccgctg gcatactgta ttttatcggt
    18841 catcactggc cgctcggtat tatttaaagg gtttgccgga tggcggcata aacgccttat
    18901 ccggcctgcc tccgaacaat atgtcgattt cgcaggcccg ataagcgccg cgccatcggg
    18961 caatggcaga ttatttaaat cccaccaccg gatgctgctt gtacggtgtt tcgagttcgg
    19021 caatctgctc cggtttgagc gttaaatcaa cggcattcag caactcatct aactgctctt
    19081 cacgcgaagc gccgataatc ggcgcggcga cgcctcgttt gctgagcagc caggccagcg
    19141 caacctgcgc tcgcgttgcg ccaagcgcct cgctgacgcc agccagccgt tccgctattt
    19201 gcgcatcatt tttatcgctt tcatcgtata aatttttgcc cacgtcatcc gaggccagcc
    19261 gggccgtggt ttctccccag gggcgagtta agcgcccgcg cgccagcgga ctccacggaa
    19321 tcacggcgac cccttcctgc cagcacagcg gtagcatctc acgctcttcc tcgcggtaga
    19381 tcaggttata gtgatcctgc atagtgacaa acggcgccca gccgtgttgt ttttgtagcg
    19441 ccagcgcctg ggcaaattgt gaggcgtgca ttgaggaagc gccgatatag cgggctttac
    19501 ccgcctttac cacgtcgttt agcgcttcca gagtttcttc tatcggcgtg gtgtaatccc
    19561 agcggtggat ttgcaggata tcgacatact ccattcccag acgggtgagg ctatcgtcaa
    19621 tagagcgcag gatttgcgcg cgggacaatc cttccggcag atcgccgacg cgatggaaga
    19681 ctttcgtcgc taccaccacc tcgtcgcgcc gggcaaaatc acgcagcgcg cgaccgacaa
    19741 tctcttcgct gctgccgtcg gagtagctgt tggcggtatc aaaaaagtta atgccgccct
    19801 caagggcgcg cttgatgatg ggacggctgc tctcttcggg aagcgtccag gcgtgattgc
    19861 cgcgactcgg ctcgccgaat gtcatacagc ccagacaaag gcgggacacc cgaagatcgg
    19921 tatttcctaa cgtgttgtat tgcatgactc cgctcctgtt atacccgtca ctcttcaagc
    19981 atagcaggag caaagaggag attatgccag ccaggccttg attttggctt caatgcctgc
    20041 ggcgtcaagc cccagttccg cgcgggcttc ttcctgcgtt ccttgcggga taaagaaatc
    20101 cggaagaccg atattcagca caggtacagg tttacgatgg gccattagca cttcgtttac
    20161 gccgctgcca gcgccgccca taatggcgtt ttcttccagc gtcaccagcg cgtcatgctg
    20221 cgcggccatc tccagaatta acgtgtcgtc cagcggttta acaaagcgca tgtcgaccag
    20281 cgtggcattc agcgcttcgg cgactttcgc cgcctcaggc attaaggtgc caaagttcag
    20341 aatcgccagt ttttcgccat gacgcttcac aagaccttta ccaataggca gtttttccag
    20401 cggggttagc gccacgccct gcgcattacc gcgtggataa cgtactgccg tcgggccgtc
    20461 gttatagtga tacccggtaa ataacatctg gcgacattcg ttctcgtcgc ttggcgtcat
    20521 gatcaccata tccgggatgc agcgcagata ggagagatcg aacgcgcctt ggtgtgtttg
    20581 cccatccgcg ccaacgatac cggcgcgatc gatggcgaac atgaccggca gtttctggat
    20641 agcgacgtca tggatgacct gatcgtaggc gcgttgcagg aaagtagagt agatcgccac
    20701 gacgggctta tagccgccaa tcgccagacc tgcggcgaag gtgacggcat gctgctcggc
    20761 gatagcgacg tcaaaatagc gatccgggaa tttacgtgaa aattccacca tgccggaacc
    20821 ttcgcgcatt gccggggtga tcgccatcag cttgctgtct ttggcggcgg tttcacacag
    20881 ccagtcaccg aagatttttg aataacctgg cagaccgccg ctgcttttcg gcaaacatcc
    20941 gctggaggga tcaaatttag gcaccgcatg gaaagtgatc ggatcttttt ccgcgggctc
    21001 atagccgcgg ccttttttgg tcatgatatg caggaactgc ggccctttca ggtcacgcat
    21061 gttcttcaat gtgctgataa gccccatgac atcgtgacca tcgaccggcc cgatgtagtt
    21121 aaagcccagc tcttcgaaca gtgttcccgg cacaaccatg cctttaatat gttcttcggt
    21181 acgcttgagc agttctttaa ttggcggtac gccggagaag actttttttc cgccttcgcg
    21241 cagagaagag taaagcttac cggaaagtag ccgcgccaga tggttgttga gcgcgccgac
    21301 gttttccgaa atcgacattt cattgtcgtt cagaatgacc agcatgtcgg gtcggatatc
    21361 gcctgcgtga ttcattgctt caaacgccat accggcggtg atggcgccgt cgccaatcac
    21421 acagacggtg cggcgatctt tgccttcttt ctccgccgcc acggcaatac cgataccggc
    21481 gctgatggag gtggaggaat gcccaacgct cagcacatcg tattcgcttt ctccgcgcca
    21541 cgggaacggg tgcagaccgc ctttctggcg aatggtgccg attttgtcgc gacgaccggt
    21601 aaggatttta tgtggataag cctggtgtcc aacatcccag attagctggt caaacggggt
    21661 gttgtagaca taatgcagcg ccacggtaag ttctaccgtg cccagcccgg aagcgaaatg
    21721 cccgctggaa cggcttacgc tgtcgagtaa gtagcggcgt agctcgtcgc agagtttcgg
    21781 cagactctct ttcggtaaca gtcgtaactc ctgggtggag tcgaccaatg ccagggtagg
    21841 gtatttggct atatcaaaac tcatcgcaag ctcattggat atggggttta tttatcacgc
    21901 tggattatgt agttcgctag cgcttccagt gccgaggtgt ccagtgattg cgcggccagc
    21961 tgatgtaacg actgacgggc gtcctctatc aggtcccggg ctttattccg ggcttgctca
    22021 agacccagaa gtgcagggta ggtacttttg ccaagctgct ggtctgcgcc ctgacgttta
    22081 cctaacgttg cagtatcgcc caccacatcc agaatgtcat cctgaacctg gaaggcaagg
    22141 ccgatactct ctgcatagcg gtcaagtatc ggcagagtat tccgtccttt atcgcccgcg
    22201 ctcaacgcgc caagtctaac ggcggcgcga atgagcgcgc cggtcttatg gcgatgaatg
    22261 cgttccagcg cgtccagagt gatccgctgg ccttctgccg ccagatccaa tgcctgaccg
    22321 ccgcacatac cggcgatacc gctggcgttt gccagttcgg cgatcatcgc gatacgatcg
    22381 cgatcggcga cttccggcat cggcgcgtcg ctgataatgg taaacgccag cgtttgcaac
    22441 gcgtctcccg ccaggattgc gttggcttcg ccaaatttaa tatggcaagt cggcaggccg
    22501 cgacgcaaat cgtcatcgtc cattgctggc aggtcgtcat ggatcagcga ataggcatga
    22561 atgcattcga ccgccgcagc tggcgcatcc agcgttgccg tactgacgcc aaacatttga
    22621 ccggtggcgt aaaccagaaa tggccgcagg cgtttaccgc ctaataatgc gccatactgc
    22681 atggcttcga ccacgggagt gttctgaaag ggcagtggcg cgataaaacg gctcagcgcc
    22741 tgattcgctt gcgttacgca agcctgtagc tgctgcgtaa agtccattta ctcattatcc
    22801 gcgataaaag gctcaggtga agcctcttca ttatcagaca gcaaaatttg cacgcgctgt
    22861 tccgcctgct gcagttttgc ctgcccctga cgcgccagtt gtacgccgcg ctcgaattca
    22921 ttcagcgcgt cttccagcgg caaatcgccg ctttccaggc gggtaacaat atgttccagc
    22981 tcgctcagcg cagtttcaaa gctggcgggc gcctcatttt tcttcggcat gatgactgtt
    23041 tgactctctg taatggcagc acaagtctat ggtaacggac tcgcactgat aagcaaataa
    23101 cgcgcaatgg taaggggaaa tgcgcaagat gtccgtgatg gtgatatact tccgcgcctg
    23161 gatgcagccg taggtatggg ctgctgtact atttctccac gacaagcctt agatagcttg
    23221 ctaaagaacc attaccgcca tgaagtttat cattaaattg ttcccggaaa tcactatcaa
    23281 aagccaatct gtgcgtttgc gctttataaa aattttaacc gggaacatcc gtaacgtttt
    23341 aaagcactac gatgagaccc tcgcggttgt ccgtcactgg gataacattg aagttcgcgc
    23401 caaagatgaa aaccagcgtc tggcgattcg cgacgcgctg acccgcatcc cggggattca
    23461 ccatattctt gaagtcgaag atgtgccgtt caccgatatg cacgacattt tcgagaaagc
    23521 gttggcgcag tatcgcgaac agcttgaagg caaaaccttc tgcgtgcggg taaaacgtcg
    23581 cggtaagcat gagtttagct ccattgaagt ggagcgctat gttggcggcg gattaaatca
    23641 gcatattgaa tcagcgcgcg tgaagctcac taacccggat gtgacggtgc atctggaagt
    23701 ggaagatgat cgcctgctgc tgatcaaagg gcgttatgaa ggtattggcg gtttcccgat
    23761 tggcacccag gaagacgtgc tgtcgctgat ctccggcggt tttgactcca gcgtctccag
    23821 ctatatgctg atgcgtcgcg gctgtcgcgt acactactgc ttctttaacc tcggcggcgc
    23881 ggcgcatgaa atcggcgttc gccaggtggc gcattacctg tggaaccgct ttggcagctc
    23941 ccatcgcgtg cgttttgtgg cgattaactt tgaaccagtg gtcggcgaga ttctggagaa
    24001 agtcgacgac ggccagatgg gcgtggtgct caaacgtatg atggtacgcg cggcgtcgaa
    24061 agtggcggaa cgttacggcg tacaggcgct ggtgaccggc gaagcgctgg gccaggtgtc
    24121 cagccagacg ctaaccaact tgcgcttgat cgataacgtg tctgacacgc tgatcctgcg
    24181 cccgctgatc tcttacgata aagagcacat tatcaacctg gcgcgccaga ttggtacgga
    24241 agattttgcc cgtacgatgc cggaatactg tggcgtgatt tcaaaaagtc cgacggtgaa
    24301 agccattaaa gcgaaaattg aagccgaaga agaaaatttc gacttcagta ttctcgataa
    24361 ggtggtagaa gaagcgaaca acgtcgatat tcgtgaaatc gcccagcaga cccagcagga
    24421 ggtggtggaa gttgaaaccg tgagcggttt tggcgccaac gatgtgattc tggatatccg
    24481 ttctgtcgat gagcaggatg acaagccgct gaaagtggaa ggcgtcgacg tcgtttcgct
    24541 gcctttctac aagctgagca ctaaatttgg cgacctcgat cagagcaaaa cctggctgct
    24601 atggtgcgaa cgcggcgtaa tgagtcgcct gcaggcgctc tatctgcgcg agcaggggtt
    24661 tgccaatgtg aaggtgtatc gcccgtaatt cctttgccgg gtggcggcta tgtcctaccc
    24721 ggcctaccgt tttatttcta ccccaaccgt tttgcaatgc gctccagctt catcatcagc
    24781 agcagcgtaa tggccaccag cacaatggtc agcgccgcgc cgtcggcgat atttccacgg
    24841 tcggtcaggc taaagatagc taccggcagc gtcgtccagc ccggtggata aatcatcacc
    24901 gtcgcgccca actcccccat ggagagcgat aaactcagcg ccagctctga caccatccac
    24961 ggcatcaata acggcaacgt cacgtgacgc agacgatacc agggcgatgc ccccagactc
    25021 gacgcgacgt tttcaatatc ggcggaaatg cgcgccagtc cggtcgacac gttactgaag
    25081 gtaaaggcgg aaatcagcac aaagtgcgct gtcagcacaa tccatagggt gccgttcatt
    25141 tgcaatggcc cctggctgaa agcaaccaga atgcccaggc ccacggacac tgacggaatc
    25201 gcactcggca gatagaacac catacttaac catttctgcg ttttcacccc atattgacgc
    25261 aacgccagcg ccgcccaaac gccgcaaagc agcgcaaaca ggctggcgca aaagccaatc
    25321 gtgaggctgg caagtagggc atcccatgcc gcaccgtgca gagcgttaac aaagtggttc
    25381 agcgtgaagc cactcggcag aataccgttc caccgctggc taaggctgga catcagaatc
    25441 accgccagcg gcaggaaaaa gaacacgata aacagtacgc tagccacaac gcccgccgct
    25501 gcgcgtcctt taggtgacca aattagcatg gctggctcct tacgccggta cgcgatgccg
    25561 ccaggcgata gagggagaac agccccagcg acaagacaat gttaatcaac gcaatcatgc
    25621 aggcgaccgt atagtcggac tccagaatcg ctttgctgta aaccatcatc ggcagggtgt
    25681 taaccccttt cgcgccaata aacagtacga tgccgaactc gttagtggtc aacagcaggc
    25741 acaggctgcc actagccatc agcgccggta gcgccgccgg gaaaatcacc tgcccaatca
    25801 cccgtaacgg gtgtgccccc agaatgctgg ctgcctctag ctggctttta tcaatttgcc
    25861 gcagcgcggc catcagtggc cgcatcacca gcggagtgaa caccgtgatc tccgccagaa
    25921 tgacaccctg catcgagtag agaaaatcca ccggcggtag ctcaaaggca aacaggctca
    25981 tcagcgcacc gttgagcaga cccgctgacc cataaataaa ggtgaacgcc agcgtaatca
    26041 ggaaggtcgg cagcgcaata aaagtatcga cgacccgacc aatcaactcg ctgccgggga
    26101 aaggaataaa caccagaatc agcgacatca cgctgcccag cagcaggcaa ccggcggtgg
    26161 cgaaaaaggc gatttgcaac gtgttcagca acgcgccgac aaagcgtttc gagtcgacca
    26221 cctggcggaa ggtctcgagc ccgatctcgc cattggcacc gcgtagcgcc tgttcaacga
    26281 tgagcgacag aggccagaaa aacagcgtcg ccagcgccag caacgggagc aacagccaca
    26341 gcagcgggcg taggttaagc gccggttttt ccagaggtaa aatgagtgac atggttatac
    26401 ctcaatcagg accgcatcat ccggttcgaa ccacagcgcc agcttgtcgc ccacgcgcgg
    26461 cagcggattg acatgcgtca acaccatccg caccgtttcg ccagcaacgt cacacaacag
    26521 atgggttaaa tcgccttgcc agtgcaccga ttgcagtgtg gcgttgaagc ggttgctgta
    26581 ggccgaacgc ggcgttaggc tgaggtgctg aggacgaatg cacagcagtt tgttgtaacc
    26641 gtggtggctg ccctggctga acgcgcgaat caccgcaccg ccgcagctga cgtccaccag
    26701 ccccggaacc tccgttatcc ccagcgcgat ggcggagaga atattggcgc gacctaagaa
    26761 ttcggcggca aaacgattgg gcggatggtg atataacgcg cgggtttcgc cgtgagcaat
    26821 cagcgagcca tccttcataa tgccgatttt atcggccagg gtgagcgctt ccgtttgatc
    26881 gtgggtgacg tagagaatag tgagttccgg cagctcacgg tgaagacggg cgatttcttc
    26941 caccatatta tgacgaatct gtgcgtccag cgctgacagt ggttcatcca gcaacagcac
    27001 gcgcgggcgc acggcaatcg cgcgggcgat ggccacgcgt tgctgctggc cgccagaaag
    27061 ttgatgcgga taacgggtgg cgtaatcact catgccaact gtcttcagcg cctgcgtgac
    27121 acgctcatta attagcgcct ttggctgctt ctgcgcacgc agaccaaaag cgacgttgtc
    27181 ttccactttc agatgcggga acaaggcgta gttctgcacc accatcgcca acccgcgttt
    27241 atagggtggc agatgggtga cgtccgtatc gccaatcagg atacgaccgc ctgcaggctg
    27301 cacaaagccc gccaccgcac gcagcaccgt cgtttttcca gatcctgatg ggccaatcag
    27361 cgccagcact tcgccaggtt caatcgtcaa agagagcggt ttaagcacca cgttgccgtg
    27421 atacgcaaca cgcagcgagt cgaggactat ccccgatgtc ccctgcgatg caggggcgtg
    27481 aacggcagtc gttttcatca gcatcaggct tactcgcttt cggtcacttt gtgccaacgg
    27541 ctaatatctg ccgacagcga aacggctacg tcatcccaat ttggctgcca gctctgcacg
    27601 ccttctaacg cggcagtggc ggccttgtaa tgttcgtcgc tcggcgtcac gtcgctgcgt
    27661 accggcattc cccaggagag ttcgctgacg cgagtctgcg cttctttact cagcaggaag
    27721 ttaatcagct ttttaccatt ttcactctgc ggcgccccct ggaccaggcc aatgacataa
    27781 gggatggcca gcgcgctgcg ctcgcctttg tcgttggccg gccagaagat tttcacgttc
    27841 gggttacgtt ccatctgcgc gaggttcatt tgcaggtcgc cgttagcgac gtagatttca
    27901 cctttattaa ccagcgcggt tagcttgccg gtagaggcag atggcccgac gttattggcc
    27961 tgcagcttgc cgagatacgc aaaactggca tctttactgc cgaagctgtg gaaagcctgc
    28021 agcattaccg ccgtgccgtc agcggcctga cctggcgtgg aatactggag tttatttttg
    28081 aatttaccgt caagcagatc ctgccagctc gccggggcag ttttcagcag cttgctgttg
    28141 tagataaagc tcagataatt ctttaccagc ggcgaataaa ggttgttggc atcggggata
    28201 gccgaggcgg cgtcggtgtt aaagttcgcc agcagctttt cggcggcggc gcgctgaatg
    28261 aatggcggcg cggttaccag cacgtcggcc tgtggattcg tacgctcttt tgccagacgt
    28321 tccactacca cgccaccacc gccttcaaca tagcgtatgg taatgccggt cgctttggtg
    28381 aacgcgtcaa actgcacctg gtaccagctg ttatcgccat cgtgcagccc gtcgatggag
    28441 tacaccgtga ccactgattc cgcccatgac ggggcgctgg cgagagcgaa gacagacagc
    28501 agagcaagtc gggaaagttt catcgtaata gcctcatagc gtacgttgca ttttctggcc
    28561 tataccaggt ttgcttttta cgctaaacgg cttatatgac aaaacgatga aagagaaata
    28621 aatcagtcca cgccggatga tgctgcgctt atcgggatag ccgtgagacg atacgattga
    28681 caggccggat aaggcccgca gccaacatcc ggcgcacccg ctagtgggta tctacctcaa
    28741 tgcgcaggct gtcgtgacgc cagtattcga tatccagatc cagcactcgc ccgtgttgat
    28801 cgtagttcag acggcgcagc aacagcgccg ggcgtccttc cataactccc agcgcctgtg
    28861 cggcctgcgc aggcatggcg gtggggtaga acgacagatg catgctggta tagacgaggt
    28921 tgtagtgcga ctcgtatacc tcggtcaggc tgccgttgag atcgtactgc agcagctcag
    28981 gcacgcgggc gggcaaacaa tggttttcgc agtagcacac ggcgcggcca tcggcgtaac
    29041 gcagacgggt cagcagatag atttgatcaa acggctggag ctggaggggc tccatgacct
    29101 cgacaggcac ggtggttaac acgccgctca gtagcgcggt ttttggctcc cgcccctgct
    29161 cgcggcaaag cttatggaag ttggtgttct gggtcggatc cagccacagg cgttccggcg
    29221 taacgaacca accgcgacga tcggcgcgcc agataagccc actggactcc agctgcgcca
    29281 ggctttcgcg aatagtaatg cgcgtggtgt tgaagatcgc gcacagttcg cgttcagacg
    29341 gcagtttatc accgcttttc aacgcaccgc tctgaatacg cgcctgaagc tgcgccttga
    29401 tcaacaggta ctgcgggata tcgcccggga tagatttcat gcttactcgc ttccgtttta
    29461 cctgccgcca ttatacaagc agagatgaat tttttgttgc agcgcgattt tctctttgac
    29521 ccatcgcggc aaagatcgtc atgataaatg caatctggta tagaccaaag gtaaatgata
    29581 tgacttcgcg taactatctg ttgctgaccc ctggcccact caccacctct cgcaccgtga
    29641 aagaagcgat gttgttcgat agctgtacct gggatgatga ttacaatatc ggcgtggtag
    29701 aacagatccg ccagcagttg accgcactgg caacggcctc cgaaggctac acctccgtac
    29761 tgctgcaagg cagcggcagc tatgctgtgg aagccgtact gggaagcgca ttggggccgc
    29821 aggataaggt gctgatcgtc agcaacggtg catacggcgc acgaatggtc gagatggccg
    29881 gccttatggg tatcgcccat cacgcttacg actgcggcga agttgcgcgc ccgaacgtgc
    29941 aggcgatcga cgcgatcctc aacgccgacc cgacgatcag ccatatcgcc atggtgcata
    30001 gcgaaacgac caccgggatg ctcaacccca ttgatgaggt tggcgctctg gcgcatcgct
    30061 atggcaaaac ctacatcgtt gacgccatga gcagcttcgg cggcatcccc atggatattg
    30121 cagcattaca catcgactat ctgatcagct ccgctaataa atgcatccag ggcgtgccgg
    30181 gttttgcctt tgtgattgcc cgcgagcaaa aactggccgc gtgcaaaggg cgttcccgct
    30241 cgctgtcgtt agatctctac gcccagtggc gctgcatgga ggataaccac ggcaaatggc
    30301 gttttacttc gcccacacat accgtcctgg cgtttgcaca ggcgctgaaa gagctggcga
    30361 aagaaggtgg cgtggcggca cgtcatcaac gctatcagca aaatcagcgc agcctggtgg
    30421 ccggaatgcg ggcgctgggc tttaacacgc tgctggatga cgagcttcat tcgcccatta
    30481 tcaccgcctt ttattcaccg gaagacccgc agtatcgctt tagcgaattt tatcgccgcc
    30541 tcaaagagca gggctttgtt atctatccag gcaaggtgtc gcaaagcgac tgcttccgca
    30601 tcggcaacat tggcgaagta tatgccgccg atatcactgc cctgctgacc gccattcgta
    30661 ccgccatgta ctggacgaaa taaggaacca tgatgaaccg tattcacgct gttattctcg
    30721 actgggcggg caccaccgtc gattttggct ccttcgcgcc gacgcaaatt ttcgtcgagg
    30781 cgttccgtca ggcatttgat gtggagatca ccctcgccga agcacgcgtg ccaatggggc
    30841 tgggtaaatg gcaacacatt gaagcgctgg gaaaattacc tactgttgac gcgcgctggc
    30901 aggcaaagtt tggccgcgcc atgagcgcag cagatattga tgccatctac gccgctttca
    30961 tgccgttaca gattgctaaa gttgtcgatt tttcttctcc tattgccgga gttatcgaca
    31021 cgatcgcgac gctacgagcc gagggtatca agataggctc ctgctccggt tacccacgag
    31081 cggtgatgga gcgcctggtt cccgccgccg ctgagcatgg ttatcgtccg gatcattggg
    31141 tggcaacgga cgacctggtc gcgggtggtc gcccggggcc gtggatggcg ctgcaaaacg
    31201 tgattgcgct gggcattgat gcggtcgcgc actgcgtgaa ggtagatgat gccgcgccgg
    31261 gcattagcga ggggcttaac gcggggatgt ggacggtggg gctggcggta tcgggtaacg
    31321 aattcggcgc aacatgggac gcctatcaga caatgtcgaa agaggacgtt gcggtccgcc
    31381 gcgagcacgc ggccagcaag ctgtacgccg ccggggcgca ttacgtggtg gattcactgg
    31441 cggatttacc tgaggtgatt gcgcatatta atgcgcgtct ggcgcagggc gaacgcccgt
    31501 aaaataactg ccggatggcg ctgccgctta tccggcctac agactgtacc gttttgtagg
    31561 ccggataagg tgtttacgcc gccatccggc aatcattctt attcgtagta gttataaatc
    31621 cccgccgcca tcaccagttg cgaagccact tcatgcgctt tttcacgacc aaccaacagg
    31681 tcgatgattt tcaagccaaa atcgatagcg gtacccggtc cctggctggt taataatttt
    31741 acccgcgcat cccacaccac acgcttatcc tgccactgtt cggcggggat cttatctttc
    31801 agcgccggaa aaccggtcat attgccgata gggaagatat cgtgcggcac gagcactgta
    31861 gcggctgcgg cgcaaatggc tgcgacaatg cgcccggagc ggtgaaactg ttttacggtt
    31921 tcgaccagca gcgggctgtc gcgaaagcac tcggcgcctt taattccgcc gggcaacacg
    31981 atgatgtcat aatcgccgtc ggcaacttca accagcggcg catccgccag cagcttcacg
    32041 ccgcgcgagc agacaatcgt caggttgcca tcgctggcga cgctggcggt agtgacgtgg
    32101 attccgccgc gaaccagcag atcgatagtg gtgaccgctt cggtctcttc actaccaggg
    32161 gcgaggcata ccagtgcctg agcgctcata ctcactctcc tttcgcttta ccatttcaaa
    32221 caggcggcta ttttccggaa cggcgagacc gtgcacgcgg gcgcgcttga gtaaataacc
    32281 ggtgatgtag tcaatttcgg tatggcgcat ggcgcgcacg tcctgcaaca tggatgagat
    32341 attttctgcc gtactgtcaa tcacttgctc aacataatag cataaatcgt ctgccgatgt
    32401 gtggtagccc tcacgttcaa tcacggcggc gacctcttcg caaatcgcgt tgatttcatc
    32461 agtatgatgg cgcagctcgc cgttcgggca gttccaaagc gcggtgagcg ggttgataac
    32521 acagttgacg gccagtttgc gccacatctc tgcgcggata ttgttatgcc aggcgacatc
    32581 gggcagtacc ccttgcagga tctcggcgag ataactgtaa tcgccgtctt gctcgcgcgc
    32641 cgggccaata tgcgtagtac cgttagcgac atgaataatg atattaccgt cgcggcgcgc
    32701 agcatgggtg atagtcccca tcaacatcgg ctgttggata ctttgcagtt cttctatggt
    32761 tcccattcca ttatgaatga gcaggatagg cgacgtcacc ggtagggttg acgccagggt
    32821 tcgtactgcg tcggaaacct gccacgcttt cagcgtgact aacaacagtt cgctcttcgc
    32881 caaaaaatcc ggatcgtttg ccgtcagtga ttcgttgaaa aaggaaccat cggtatcgat
    32941 cagatttacg ctgcaataag gttgtggcac ccgtagccag ccctgtacgt catgtccatg
    33001 tttgcacagt gccgaaagcc aaagttgtcc taaggctccg catcccagta cagtaatttt
    33061 cattgttcct cctcacctgc aacagcgcca ggtgttatgg cgctaattat agcgtcatca
    33121 gctaagcttc tcgttaagcc tcgttgcagg tattatgcaa cgcaacgaaa atgaagggag
    33181 aagaaaagat gccatctttc gatattgttt ctgaagttga tctgcaggaa gcgcgtaacg
    33241 gcgtggataa cgcggttcgc gaggttgagt ctcgttttga ctttcgtggc gtagaggcga
    33301 ctattgaact gaacgatgcc aataaaacca tcaaggtgct gagcgagtcc gatttccagg
    33361 tcaatcagtt gctcgatatt ctgcgcgcca agctgcttaa acgcggtatt gaaggcgctt
    33421 cgctggatgt accggacgag ttcgtgcata gcggtaaaac ctggtatgtg gaagcgaagc
    33481 tgaagcaggg cattgaaagc gccgtgcaga agaaaatcgt caagctgatt aaagacagca
    33541 aactgaaggt gcaggcgcaa attcaggggg aagagattcg cgtgacgggc aaatcacgtg
    33601 acgatctgca atcggtaatg gcgctggttc gcggcgacga tttaggccag ccgttccagt
    33661 tcaaaaactt ccgcgattaa gttgttatgc cggatagagc ctcgccgcca tccggcaatg
    33721 ctgcattcat cctttgctga taagctgttc aacttcaaag cgattggtca ctttgctgtc
    33781 gattttgacg taagcggaat gctcttccgc cacgatcagc gcttcgctta cgcctttcat
    33841 tgccaacagt cgctgtttta gcctgtcgtc agcaacgata tccgctggaa tttccacacg
    33901 caggctgctg acatagggcg gctctttcat ggtacttgcc accgccagcc ataccatcgc
    33961 cagtacggcc ccggcaagga aaacggtttg cccatcaaac gtgccgtcta tccagccgcc
    34021 cagcgagccg ccaagcgcca cgccaagaaa ctgactggta gaatagacgc ccatcgccgt
    34081 tcctttatac cccgcgggcg actctttgct aataagcgaa ggcagcagcg cctccatcag
    34141 attaaaggcg aggaaaaaga gttgtacgcc aatcaccagc tcccagaaat gctggcccgc
    34201 tccccacaac acgatttctg cgacgataat gagccccacg cagaacagga atacctgctt
    34261 catccgccgt ttgacttcag catagatgat aaaaggcacg acggcggcaa aggcgatcac
    34321 catggttgcc agatacacct tccagtgttc ggcggcaggg aaaccggcat cggcaagctg
    34381 gccgggcagg gcgacaaagg tggacatcaa taaaatatgc agacacatga tgccgaagtt
    34441 gagcttgagc agcctcggct ccgccagcac tttactgaag ctgcctttga ccatcccgga
    34501 ttcgcgattc agcacatggt tggtactgtt gggaaccacc cagatcgtca gaagaatgcc
    34561 cagggtggcg agggcggcga tcatccagaa caacgcgttc aatcccagac tatgggtaac
    34621 aatcggccct aataccatcg caatcgcgaa ggtgatacca aagctgacgc cgataaacgc
    34681 catcgctttg gtgcggtttt gctctcgggt cagatcagac aggagcgcca tgacggcggc
    34741 ggcaatagcg ccggacccct gtagcgctcg ccccagaata atgccccaga tagagtggga
    34801 gagcgcggca atgacgctac ccgcgacaaa taccgccagt ccgccgacaa tcagcggttt
    34861 acggccaatg cggtcggaca gcagcccaaa gggaatttga aagatagcct gcgccagccc
    34921 gtaaataccg atcgcaatgc cgattaatgc ttcgctggcg ccctgtagcg ccataccgta
    34981 tgtggtcagt actggtagaa ccataaacat gcccagcata cgcaacgaaa agacggtccc
    35041 taaaccccat gtggcgcgca gctcccctgg cgtcatttta taatcgttca ttgccacctc
    35101 tgtataaaag ctgggagtag tgtagtgcgg ggagtgtgcc gggtaaatag agggttaatt
    35161 agcaaatatt atgtttttga aacagttgag ctaaaaaaga gataaattgt taacacgata
    35221 ggggcgatcg ggagagtcag catagccttg tgctcattca tattccgatc tccttgagct
    35281 gtagtggcta tctgagccat ctcagtatag tgtagcggtt agccacggcc ttcaggctgt
    35341 gtacgctgtt gcttcatata gcaatagcag gctcgtcaag tcagactgtc agcgaaccgc
    35401 gctgcctgag tgtggctggc cagtgggtga ctttaaactt ttgctttgcc atagggaccc
    35461 gattctgaaa cgatggcaat gatcagaacc gtccatctcc tgaaaatttg atttattcaa
    35521 caacgccgag actgatagca aactttctgc gtgatggcgc gcgtttatca ggcagaaggt
    35581 tagtcatcag tcttatttat tatattattc aaggagtgaa ttagttgtga aaattaaatt
    35641 cttatcatta tgtattttag caggtgtttt atttgctaac caggtgaatg catcagagaa
    35701 caacagtaaa gatgatgtaa aatacgctgc gcttacccag aaggattttg atgctttgcc
    35761 tgtggaaaaa agagcttcgg ttctggatga actggggttt atccatgaat acggccttaa
    35821 tgtaccgatg aatcgcgaac aggcgttgca gtattataag caggcctgtg agcttggcgg
    35881 taactacggt tgctataatg tgaagtatgc ttatcagcat ggcgacggag tggcgaaaga
    35941 tagcgctcag gccaataagt atgctaaaaa aatgaatctg gataatttat tgattgagca
    36001 agaatatatt gacaagtttt cgcaagaaat ttacgtggcg aaagcattgg ccgatatgga
    36061 taaatcgcag cgggcggcat ttattagtat actaattcat gctctaaata atagacccga
    36121 gagcgatgcg ctttttttag tcgtatcgga tttaatcagg aaaaaacgtt ccgccttgct
    36181 acgctatggg ggcaggacgg cgatccacaa atggattatc aactggggtt actcaccctt
    36241 aatgatttct ctggccatta tgtggatgag ccttataaag ccaggccggc ctcgttgaaa
    36301 tggtttcgcg ccgccgcgga aaaaggcgtc gttgaggccc aatctctctt ggggggtatt
    36361 tattcggggg gagagggcga tgagtggggg attaagccag acattcagga agcgcaaaaa
    36421 tggtatgggc aggcgtctga gcagggggac agcgatgcac agattgcgtt aggtaaaatc
    36481 tattattctg gtgcaacagg gcgcactgat tacgctaaag cgctggcatt atttacgcag
    36541 gttgaaaatg atggtactaa ttcgcgctca acgatgccgt tgagttggat gtattataac
    36601 ggtttaggta ctgcacctga ttgtgataaa gcctggtcgt attacaagaa agcatctcga
    36661 tatgtaggta agaaagttga ggaaaaaata tttttaagta agtgcgcagc ggatattcag
    36721 agtcgaaaaa aaacgcggat gctttaccca aagtaaccct aaaaaaagag agtgttttct
    36781 ctcgcgggat aacggctaaa ccgaaagaat gtgcattaat ttttcagatt ggcacagata
    36841 aaatccgtaa catggcgaat ttgcatatta cacttgaact gaaaaatgct gatggaatgg
    36901 caactgagga aacgttgatg attccgccat tcggtttgaa tactctgggg atagatatgc
    36961 aaaatcatga tgttgatcct ctcattaccc catacgatct cccactgtat acgcaagatt
    37021 tttgtcacgg gatcggcgat atccatttta cgctgaaatc cgctacggca acgattaacg
    37081 gtaagaatgt cgatttgctg aaagctgaca gtgtgcactt tttagataaa gaataaggga
    37141 atgaaaaatg ataaagcgga aatggaatct tttgcttctg cttgggtttt ctttcgcatc
    37201 ggtatgccag gcaggtgatg atattgacgc gttatatagc cgtattgcgc agaaagatgt
    37261 tcaggcgcta aatgagctaa aagcgttagc caaagataat aatgctcaag cgctggcgga
    37321 gttggggttt atttatgagt acggcgttgc cgtgccgaaa gatacgatac aggctatcaa
    37381 gtattatgag caggcttgtc atgttgaata accctatggc tgctacaacg ctcgttattt
    37441 ttatctgcat ggcctggggg tgatgcagga tgacgttttg gcaaaagagc ttgcggataa
    37501 aaccagtaaa gcagatatcg atactgatgc gcagacggtg acgcgcctga tagccgacga
    37561 aatagatacg gcaaagcaag ccgcggaaag cgatattact cagcgttccc ggtttattga
    37621 aacattacgc cagtatgccg gcggcgggag cgcgatggcc gcgcgcatca cgcgcctggg
    37681 ttattcaaag gcggatatcc tgcaccttgc ggagctgtgg gcgcaggaga gagaccctga
    37741 acttaacttt atcgttggta gtctctatga ctctggtttt gttgaggtcg acgataaaga
    37801 ggcgcgttcg ttgcaatggt tccgcaaggc tgctgaattg ggccaggctg atgcgcagaa
    37861 tatactcggt tacttctact tgaatggaaa acgagggatt aagcgcgatc tgcagaaggg
    37921 ggggcagtgg tacgagttgg cggctgcgca gggtaatgtc gatgcgctca taaatcttgg
    37981 tgagatctat tactccggga cgcgggttcc gcttgattac gctcgggcgt ttgaattctt
    38041 tgagcgggcg gcgaagatgg gcaagtctcg cgctttaaac tatcttgcct ggatgtatac
    38101 caacggtcag tttgtcgaca cggactgccg gaaggcagcg gagttgtttg ctcaggggcg
    38161 aacaagtttt gcagacgatc cccattttca ggtgacctgc gaaaaagacc gacaggcccg
    38221 tgctgaggct gtggcaatgc gtgaaaagaa tttgccgaag ttaaccttca atcgtgatcg
    38281 tgttttcggt gcgagtcagg gcagcggcta tgcatgcgag ctggagtttg tcgtcaaaac
    38341 ggatagagtc agcagtatag agaatttacg cgtctcactg gcgctgaaaa ataaggccgg
    38401 ggcgatgtca cagcaggtta tcgcatttga gccttttggg ctaaatatgc agaaccgcaa
    38461 tttacaaggg tataagtctg atacgctacg tgaatcgaca ttacaaccta tctatcagcc
    38521 ggaattttgc gatgttgata gctatagcgt aaccgctgtg acggggattg ttaacggtaa
    38581 agagatggac attcttaagg cgggaatttt tatttaaacg cgaaaagaaa gatggcgtat
    38641 caagcgatac gccatctaaa gtctttacca gacgtaagtc agcagattct gcgaattcgg
    38701 caccataaaa tcaacagaca tcatgatact cagtgcggta atcgcaatga tagagaagcc
    38761 gaacagctta cgcgcccaga ccttatcatc ttccactttg taaccgcgta gcgccatgcc
    38821 gagccaccaa acgctgaccg ccgcggcgac caccaggtat ttgtaaccag cataaccgcc
    38881 caacgttagc attagcgttg caacggcaaa cgcaatgatg tacagcgtga tgtggttttt
    38941 agcgactgag attcctttta tcaccggcag aaccgggata ttggccgcct gatagtcctt
    39001 aaagcggaaa atggcgatgg cgtaagagtg cggcatctgc cagaggctga aaatagccaa
    39061 cagaatcgcc gcgccgctgt caaagtcgcc cgttacggcg cagtagccaa tcaccggcgg
    39121 cgctgcgccg gagagcgaac caatcagcgt tccgtagacg gagtgacgct tcatgtacaa
    39181 gctgtacacg ccaacgtaga ccacgaagcc catcaccccc agccagcagg ccaaaggatt
    39241 agcgccaaac cacagcagca taaagccagc aatacccagc agggtggcgt ataccagcga
    39301 gacgccagga gaaatcaggc ctttgaccag cacccgattc ttggtccttt ccatcttcct
    39361 gtcgatatcc ctgtcgatgt agttgttaaa tacacaaccc gacgccacaa ccagtgacac
    39421 cccgaccagc gtatagatga acaggggata gtcaatgctg ccctttgagg ccagcagaaa
    39481 tcccccgatc accgagatca ggttgccaaa gatgatgcct ggtttcgtta cttgcaggta
    39541 ttgcttaaac atcatactcg ccgctcttag tgcatcatca tgttgtagtt gaggttccac
    39601 ataatccaga tggagcccac aaccaggatg gcgatgatca gcacggtaaa gatgaaggcc
    39661 gtcatgttcc agccttcatc agatttggtg ttcatgtgca ggaaacacac cagatgcacc
    39721 aaaatctgca ccactgccat tgccaggata gatcccagaa taacggccgg agaggcagcg
    39781 ccggtcatca ccatccagaa tggaataacc gtcaggatga ccgacaggat aaagccggtc
    39841 atgtacgttt ttacgctgcc gtgggatgcg ccgccgctct cggtagaatg actcattaca
    39901 tcgcccccat cagataaaca acagtgaata cgcaaatcca aatcacatcc aggaagtgcc
    39961 agaacaggct caggcacatg atgcgggtac ggttagtgct ggtcagaccg cgacgggcga
    40021 cttgcaccat cagcaccgcc atccagatca aaccggaagt gacgtgcaga ccgtgcgtgc
    40081 cgaccagcgc gaagaacgca gacaggaagc cgctgcgatc cgggcccata ccgttaacaa
    40141 tcaggtgatg gaattcatag atttccatcc cgataaatcc ggcaccgaac aagaaggtca
    40201 acgccagcca ggagataacc tggctcttgt tgttcttgtg catggcgatc gccgccatgc
    40261 cgtaggtaat ggagctaaat aacagcagga aggtttcaac cagaacgaac ggcagttcga
    40321 aaatgtcctt acctgtcggg ccgccagcgg tgccgttcac cagaacggca taggtagcaa
    40381 acagaataga gaacagaatg cagtcgctca tcaggtagac ccaaaatccg aagattttgt
    40441 tctggcctgc gtcatggtgc ccgtgttcgt gcgcgtgggc agtcgcgtgc gttaaagtat
    40501 cagttgccat ttttcagccc tgccttagta atctcatcga aatgctggtt ttccagtttt
    40561 tcgacttccg ggaccggcac gtagtaatcc acatcttcat caaagctttt tacaatccag
    40621 ctgatgatca tgcctgcgaa acccactatc gccagccacc agatatgcca gatcatggcg
    40681 aagccaaata ccgtcgcgaa ggcggcgata acaataccgg caccgctatt tttcggcata
    40741 tgaatctctt catactgtcc aggctgttgg tacgcttcgc ctttttcttt catttcccag
    40801 aaggcgtcac gttcgtgaac gtgcggcaca acggcaaagt tatagaacgg cggcggagac
    40861 gaggttgacc actccagcgt acggccaccc catgggtcgc cggtcagatc gcggttctga
    40921 tcgcggtcgc gaatagaaac gaagatctga atcagttggc acaggatacc cagcgcaatc
    40981 agcgcggcgc cggcggcggc aaccatcagc atcgtatgga actgcggatc aatttgctgg
    41041 ctgaggcgac gggtcatgcc catgaagccc agtacgtaca gcggcataaa ggctacaaag
    41101 aaaccgataa tccagaacca gaaggcgcgt ttaccccagg tttcgttcag cttgaagcca
    41161 aacgccttcg gccaccagta agtcatacct gcgaagcagc caaacaccac gccgccgatg
    41221 atcacgttat ggaagtgcgc aatcaggaac aggctgttgt gcaggacgaa gtccgcgccc
    41281 ggtaccgcca gcagcacgcc ggtcataccg ccgaccgaga aggtcacgat aaagccgatg
    41341 gtccacatca ttgcggaatg gaagacgata cggccctgat acatggtgaa caaccagttg
    41401 aagatcttca ccccggtcgg gatggcgata atcatggtgg tgataccgaa gaaggcgtta
    41461 acgttcgcgc ccgcgcccat cgtgaagaag tggtgcagcc aaacgataaa cgacagtacg
    41521 gtaatacaga cggtcgccca aaccagcgag gtatagccga acagacgttt acgcgagaag
    41581 gtcgctgcga tttcggagaa taccccgaag accggcagaa tcagaatgta cacttccgga
    41641 tggccccagg cccaaatcag gttgatgtac atcatcatgt tgccgcccat atcgttggta
    41701 aagaaatggg tgcccagata gcgatccagg gtcagcaacg cgacggtaac cgtcagaatc
    41761 gggaaagagg cgatgatcag tacgttggcg cacaaagagg cccaggtaaa gaccggcatc
    41821 ttgaacattg tcatacccgg cgcacgcatc ttcaggatcg tcacgaagaa gttgataccg
    41881 gttaacgtcg taccaatacc cgagagttgc aacgcccata tccagtaatc gaccccgacg
    41941 ctgggactgt actctattcc cgatagcggc ggataagcca gccaccctgt ctgcgcgaat
    42001 tcacccacgc ccagcgagag gttaaccaga ataacgccga caacggtgaa ccagaagctc
    42061 aggttgttca ggaaagggaa agcaacgtcg cgcgcgccga tctgcagcgg aaccaccagg
    42121 ttcatcagac cgataacgaa gggcatcgcc acgaagaaga tcatgattac gccgtgagcg
    42181 gtaaagatct gatcgtagtg gtgcggcggt agaaaacccg cttcgcctgc ggaggcaagc
    42241 gcctgctggc tacgcatcat gatggcatcg gcgaaaccac gtaacagcat cacaatcgcg
    42301 acgatgatat acatgatacc gaggcgttta tggtcaaccg acgttaacca ctctttccat
    42361 aggtaggtcc acttaccgaa gtaagtaatc gctgccagta tcgccagtcc cccgacgata
    42421 attgcagcga tcgttaccat gacgataggt tcatggaacg gtactgcatc cagtgataat
    42481 tttccgaaca tcttatcttc ctcaaccctt ggagttggcg gattccgcgt ggctcatgtc
    42541 cataccttcc attccttcat gcgagctgtg ctcaccttca ggttgggtca tgtccatgct
    42601 cttaccgtgg cccatgaatt tgttaataac gtccttgaac aaatctggtt tcacgctgga
    42661 gaaatattcc accttgttgt actcgcttgg catagccact ttctcgaacg ccgccatatc
    42721 attcatggtg ttcggagact gcttcgcttt tgcgacccat tggtcgaatt ctgcgcggtc
    42781 tttggtggcg atagctttaa acttcatacc agagaagccc gggccgctat agctggcgga
    42841 gatgccatcg taggttccgg gttcgttggc gatcagatgc aaacgtgttt gcataccggc
    42901 catggcataa atctggctac ccagacgcgg gataaagaag gagttcatca cggagttgga
    42961 ggtcactttg aaataaaccg gcgtgttcgc cgggaaggcg atctcgttga cggtggcgat
    43021 accctgctcc ggatagatga agaaccattt ccagtccatg gaaaccactt cgatggtgat
    43081 cggtttttcg tcatgcgcca gcggcttgct tggttcaagc gcgtgcgtgg ttttccaggt
    43141 cagtacggca aggaaaatga tgattaagat aggcaccgtc cagaccacgg cttccacttt
    43201 attggagtgt gaccagttcg ggctatactt cgcatcctta ttactcgcac gatacttcca
    43261 ggcaaaacca acagccatca agatggcggg aataacgacg atcaacatca ggccaaatgc
    43321 cgtcagtatc agcgaacgtt gctccagtcc aatctgtcct ttgggatcca gcagcgcaga
    43381 attacagcca ctgagtaatg cagtgcctgc aattaatgac aaccatccca aacttttatt
    43441 gtatttcctg agtctcattt aacgacctca attccacggg acctggtggc gtttaaagtg
    43501 taggggcatt ttacggtaag gttacattac tgtaaacatg attggttctg tgttaccaag
    43561 ttctgccgcg cgtgtcacat atgttgccaa gtatgtcgaa ataactttaa gacactgttg
    43621 aaactttgcg ttataacgga tgaggtctgt aagtgggatg ttgagggata attggtataa
    43681 ccaatgtaaa aataaaacaa ttacttaaca atttattatc aa
//
LOCUS       DAJVKX010000028        41295 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000028 DAJVKX010000000
VERSION     DAJVKX010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 41295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41295
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.028"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..2240)
                     /gene="ftsK"
                     /locus_tag="OPY25_001476"
     CDS             complement(<1..2240)
                     /gene="ftsK"
                     /locus_tag="OPY25_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCS0927121.1"
                     /translation="MSQEYTEDKDVTLTKLSSGRRLLEALLILIALFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGAPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     TDDYIDYFAVSLRLIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIMLLCIWAAGLTLFTGWSWVSIAEKLGGWLLNILTFASNRTRRDDTWVDDEEYD
                     DEYDEETDGVQRESRRARILRGALARRKRLAEKFSNPRGRQTDAALFSGKRMDDDEDI
                     QYSARGVAADPDDVLFSGNRATQSEYDEYDPLLNGHSVTEPVAAAAAATAVTQTWAAS
                     ADPIMQTPPMPGAEPVVAQPTVEWQPVPGPQTGEPVIAPAPEGYQPHPQYAQPQEAQS
                     APWQQPVPVASAPQYAATPATAAEYDSLAPQETQPQWQAPDAEQHWQPEPIAAEPSHM
                     PPPVIEQPVATEPEPGIEETRPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEN
                     VPVKPTVSVAPSIPPVEAVAAAASLDTGIKSGALAAGAAAAAPAFSLATGGAPRPQVK
                     EGIGPQLPRPNRVRVPTRRELASYGIKLPSQRIAEEKAREAERNQYETGAQLTDEEID
                     AMHQDELARQFAQSQQHRYGETYQHDTQQAEDDDTAAEAELARQFAASQQQRYSGEQP
                     AGAQPFSLDDLDFSPMKVLVDEGPHEPLFTPGVMPESTPVQQPVAPQPQYQQPVAPQP
                     QYQQPQ"
     gene            complement(2375..2869)
                     /gene="lrp"
                     /locus_tag="OPY25_001477"
     CDS             complement(2375..2869)
                     /gene="lrp"
                     /locus_tag="OPY25_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HCS0927122.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNAAVKKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            3416..4384
                     /gene="trxB"
                     /locus_tag="OPY25_001478"
     CDS             3416..4384
                     /gene="trxB"
                     /locus_tag="OPY25_001478"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCS0927123.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHAAKFETEIIFDHINNVDLQNRPFRLTGDSA
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGLRLRDTQQSDNIETLDIAGLFVAIGHSPNTALFEGQLELENGYIKVQSGTHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADASK"
     gene            4498..6264
                     /gene="cydD"
                     /locus_tag="OPY25_001479"
     CDS             4498..6264
                     /gene="cydD"
                     /locus_tag="OPY25_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HCS0927124.1"
                     /translation="MNKTRQKELTRWLKQQSVISQRWLNISRLLGFMSGVLIVAQAWI
                     MARILQHMIMENIPREALLLPFILLILIFVLRAWVVWLRERVGFHAGQHIRFEIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVCVPLLIVAAIFP
                     SNWAAALILLGTAPLIPLFMAMVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAETESIRAASQDFRQRTMEVLRLAFLSSGVLEFFTSLSIALVAVYFGFSYLGEL
                     NFGHYGTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFLETPLAH
                     PARGEVELAENEPVTIDAVNLIITSPEGKTLAGPLNFSLAAGERAVLVGRSGSGKSSL
                     LNVLSGFLSYQGSLRINGVELRDLSPESWRQHLSWVGQNPQLPAATLRENVLLARPDA
                     SEQELYAALDAAWVSEFLPLLPQGVDTPLGNHASRLSVGQAQRVAVARALLNPSQLLL
                     LDEPAASLDAHSEQRVMQALKAASKRQTTLMVTHQLEDLADWDAIWVMQDGAIVEQGS
                     YAELSAANGAFATLLAHRQEDI"
     gene            6265..7986
                     /gene="cydC"
                     /locus_tag="OPY25_001480"
     CDS             6265..7986
                     /gene="cydC"
                     /locus_tag="OPY25_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HCS0927125.1"
                     /translation="MRALLPYLTLYKRHKWMLTLGIALAILTLLASIGLLTLSGWFLS
                     ASAIAGFAGIYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYQQGELLNRIVADVDTLDHLYLRVISPLVGAFVVIMIVTLGLSVLDV
                     TLAITLGGIMLLTLFIMPPVFYRAGKNTSQNLTHLRGQYRQQLTSWLQGQAELTIFGA
                     SKRYRAQMEATELQWHEAQRRQSELTALSQALMLLIGALAVMLMLWMASGGVGGNMQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASALRITELTEQKPEVTFPQAETPAP
                     EKVTLTLRDVSFRYPDQPINALNALSLQANPGEHVAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDLPLSSLSESALRRTISVVPQRVHLFSATLRDNLLLAAPNASDEALSDML
                     RRVGLENLLEDSGLNSWLGEGGRLLSGGELRRLAIARALLHDAPLMLLDEPTEGLDAT
                     TESEMLELLADVMREKTVLIVTHRLRGLARFDQIIVMDDGRIIERGTHAELLAGQGRY
                     YQFKQRL"
     gene            8031..8735
                     /gene="aat"
                     /locus_tag="OPY25_001481"
     CDS             8031..8735
                     /gene="aat"
                     /locus_tag="OPY25_001481"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HCS0927126.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQH
                     GIFPWFSPGDPILWWSPDPRAVLWPEKFHLSRSMKRFHNASPYRVTLNYAFDRVIDGC
                     ANHRDEGTWITRGIEEAYRRLHELGHAHSIEVWRDRELVGGMYGVSQGALFCGESMFS
                     RQENASKTALLVFCAEFTRHGGKLIDCQVLNSHTASLGAIEIPRRDYLDHLAALRQQP
                     LASRFWVPRTLFLPRK"
     gene            8736..9119
                     /locus_tag="OPY25_001482"
     CDS             8736..9119
                     /locus_tag="OPY25_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927127.1"
                     /translation="MFSAHFLLGCYNCCRRIGLAHYHAARCQVTPIVYFTVPLYVALM
                     SIHQAVVSGKRCITRRCRVSRNHVLNLVCCVLNAQIFTYQKKFGIILPVQIMVVIPQR
                     IRWPKKTILKCKVPFSKRYLIPCSA"
     gene            9047..9265
                     /gene="infA"
                     /locus_tag="OPY25_001483"
     CDS             9047..9265
                     /gene="infA"
                     /locus_tag="OPY25_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCS0927128.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(9356..10267)
                     /locus_tag="OPY25_001484"
     CDS             complement(9356..10267)
                     /locus_tag="OPY25_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0927129.1"
                     /translation="MIKTDLNDFAWFVHVVEEGGFAAAGRALDEPKSKLSRRIAQLEE
                     RLGVRLIQRTTRQFNVTEVGQTFYEHCKAMLVEAQAAQDAIAALQVEPRGIVKLTCPV
                     TLLHVHIGPMLAKFMARYPDVSLQLEATNRRVDVVGEGVDVAIRVRPRPFEDSDLVMR
                     VLADRGHRLFASPDLIARMGIPSAPAELSHWPGLSLASGKHIHRWELYGPQGARAEVH
                     FTPRMITTDMLALREAAMAGVGLVQLPVLMVKEQLAAGELVAVLEEWEPRREVIHAVF
                     PSRRGLLPSVRALVDFLTEEYARMVEE"
     gene            10376..11236
                     /locus_tag="OPY25_001485"
     CDS             10376..11236
                     /locus_tag="OPY25_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HCS0927130.1"
                     /translation="MKQITGVYTAPRPHWVGDGFPVRSLFSYQSHAQQLNPFLLLDYA
                     GPHTFTPGNEKRGVGEHPHRGFETVTIVYSGEVEHRDSTGRGGVIGPGDVQWMSAGAG
                     ILHEEFHSDAFTRRGGELEMMQLWVNLPMKDKMTTPGYQSITHDVIPTVTLPDDAGVV
                     RVIAGRYEETKGPAHTFSPLNVWDMRLQRNRQLTLAQPEGWSAALVVLKGNITVNGTT
                     PANEAQLVVLSQQGKTLHLEASSDASVLLLSGEPLNEPIVGYGPFVMNTKQEIAEAVR
                     DFNSGRFGQI"
     gene            11256..11933
                     /locus_tag="OPY25_001486"
     CDS             11256..11933
                     /locus_tag="OPY25_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCS0927131.1"
                     /translation="MSSPASFNGLRPVIDVNDSVMLLIDHQSGLFQTVGDMPMPELRA
                     RAAALAKMATLAKMPVITTASVPQGPNGPLIPEIHANAPHAQYIARKGEINAWDNEDF
                     VKAVKATGRKTLIIAGTITSVCMAFPAISAVAEGYKVFAVIDASGTYSKMAQEITLAR
                     IVQAGVVPMDTAAVASELQGTWNREDAAAWADVYTQVFPAYQLLIESYSKAQDVVKNN
                     EMLDSQR"
     gene            12082..12169
                     /locus_tag="OPY25_001487"
     tRNA            12082..12169
                     /locus_tag="OPY25_001487"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12116..12118,aa:Ser,seq:gga)
     gene            12528..12905
                     /locus_tag="OPY25_001488"
     CDS             12528..12905
                     /locus_tag="OPY25_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCS0927132.1"
                     /translation="MHKYLSVVKKHRVPLSDAAVDLLKDLPRLKDNNHVFPAPRAETL
                     SDMSLLAVLKRMGYIDLTQHGFRSTFREWAGEATDYQREVIEHALAHQLADKAEAAYQ
                     RGTLWPKRVALMDDWTGYSTANS"
     gene            13067..13264
                     /locus_tag="OPY25_001489"
     CDS             13067..13264
                     /locus_tag="OPY25_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004111984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927133.1"
                     /translation="MPGLIGYWKQLPTKDEYIKKHNMSKISCYSCGHEKFSDVGLIQV
                     WDNHRRILCAKCKTTLFREED"
     gene            complement(13476..15752)
                     /gene="clpA"
                     /locus_tag="OPY25_001490"
     CDS             complement(13476..15752)
                     /gene="clpA"
                     /locus_tag="OPY25_001490"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HCS0927134.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRSE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDIVNFISHGTRKDEPSQSSDLGNQPAGD
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSVEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEVGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDNAIEALTEAIKMSRAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMGEIKKVFTPEFRNRLDNIIWFDHLSGEVIHQVVDKFIVELQAQLDQKGVSLEV
                     SQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ALTYDFQSAQKHKPEAAH"
     gene            complement(15783..16103)
                     /gene="clpS"
                     /locus_tag="OPY25_001491"
     CDS             complement(15783..16103)
                     /gene="clpS"
                     /locus_tag="OPY25_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HCS0927135.1"
                     /translation="MGKTNDWLDFDQLVEDSVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            16427..16648
                     /gene="cspD"
                     /locus_tag="OPY25_001492"
     CDS             16427..16648
                     /gene="cspD"
                     /locus_tag="OPY25_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HCS0927136.1"
                     /translation="METGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVRFDVHQGPKGNHASVIVPIEAEAVA"
     gene            complement(16778..18724)
                     /gene="macB"
                     /locus_tag="OPY25_001493"
     CDS             complement(16778..18724)
                     /gene="macB"
                     /locus_tag="OPY25_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HCS0927137.1"
                     /translation="MTALLELCNVSRSYPSGEEQVAVLKDISLQIHAGEMVAIVGVSG
                     SGKSTLMNILGCLDKPTSGTYRVAGRDVSTLDPDALAQLRREHFGFIFQRYHLLSHLT
                     AAQNVEIPAVYAGIERKKRQARARELLLRLGLSDRVDYPPSQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILRQLRDRGHTVIIVTHDPLIAAQAERIIEIHD
                     GKIVHNPPAQEKKREQGVDAAVVNTAPGWRQFASSFREALSMAWLAMAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRAMGTNTIDIHPGKDFGDDNPQYRQALKYD
                     DLVAIQKQPWVNSATPSVSKSLRLRYGNIDIAVNANGVSGDYFNVYGMSFREGNTFNA
                     VQQQDRAQVVVLDANTRRQLFPNKANVVGEVVLVGNMPVIVIGVAEEKPSMYGNSNLL
                     QVWLPYSTMSDRIMGQSWLNSITVRVKDGVDSDQAEQQLTRLLTLRHGKKDFFTWNMD
                     SVLKTAEKTTYTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGISLSMFIAFMLQLFLPGWEIGFSLTALASAFLCSTFT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(18721..19839)
                     /gene="macA"
                     /locus_tag="OPY25_001494"
     CDS             complement(18721..19839)
                     /gene="macA"
                     /locus_tag="OPY25_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HCS0927138.1"
                     /translation="MRAKGKKFKKRYLVIILILLVGGMVSWRMINAPLPTYQTLIVRP
                     GDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQI
                     KEVEATLMELNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATELAVKQAR
                     IGTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTL
                     ADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFY
                     YARFEVPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVGGNRYKVALLRNGEK
                     REREVVIGERNDTDVEVVKGLEAGDEVIIGESRPGATP"
     gene            19985..20935
                     /locus_tag="OPY25_001495"
     CDS             19985..20935
                     /locus_tag="OPY25_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK/YbjX family protein"
                     /protein_id="HCS0927139.1"
                     /translation="MTQLTDNTWYTSDYISPLQLFIRLTRGQLQPGKFWRKASFRRKF
                     LIRSLVMPRATSQLLTNLTQWPKLNTLLARQPRLPIRLHRPYMAVNIKRDFALDALCF
                     HYQQMRQLLSREQQVSYLSQYGLNLAKFEAKTGELFQLDLVSLVSLDKEGESTIVVRD
                     AQLRILAEITFTLCRFNQQRTLFIGGLQGAANDVPHEIIQQATKACHGLFPKRIVMEA
                     LCQFAQVFQAEKIIAVSNDAHVYRSWRYMDKKTQMHADYDAFWESLGGERIKGNYYTL
                     PLAIARKSEAEIASKKRAEYRRRYALLDSVVEQVPATFKR"
     gene            complement(20932..22590)
                     /locus_tag="OPY25_001496"
     CDS             complement(20932..22590)
                     /locus_tag="OPY25_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459916.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HCS0927140.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPELDLYHFVREDFWFPPGDIKGREHHLHIILTFRETQPGRHRVRRYRALEACWSP
                     CEDDFHRIFYRLEGECGADGSVMTLRSFLNSDGQPLPVENINDQVRHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPDVEVTARQLDFLARELATRPQNLTDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARHRLMRRRSQNEQRSWRYLDIINRMIDKPGSRSHRVILLGLFSTLLQA
                     KGTLRLHKDARPLLLVEDPETRLHPIMLSVAWQLLNLLPLQRIATTNSGELLSLTPVE
                     HVVRLVRESSRVAAWRLGTGGLSAEDGRRIAFHIRFNRASSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREEEREHLTALPTLDMEHFMYRQGFADVFHRVAQLPLNVPMNTRKIITKAI
                     HRSSKPDLAIEVAMEAGRRGIDAVPPLFRKMFSRVVWLARGRAD"
     gene            22791..23690
                     /locus_tag="OPY25_001497"
     CDS             22791..23690
                     /locus_tag="OPY25_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine exporter LysO family protein"
                     /protein_id="HCS0927141.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRHKAALQLINRLLSWIVYLILFFM
                     GISLAFLDNLASNLVAIFHYSAVSITIILLCNIAALLWLERILPWRHHHQQEKLPSRI
                     AMALESLQLCGVVVLGFIIGLSGLSVLQHATEASEYTLIFLLFLVGIQLRNSGMTLKQ
                     IVLNRRGMMVAVVVVASSLLGGVINAFILDLPLKTAMAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELLAIMLIPGLVRRSRSTALGLCGATSMDFTLPVLQRSGGVEIV
                     PAAIVHGFILSLLVPLLMAFFSA"
     gene            23834..25486
                     /gene="hcp"
                     /locus_tag="OPY25_001498"
                     /gene_synonym="priS"
     CDS             23834..25486
                     /gene="hcp"
                     /locus_tag="OPY25_001498"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HCS0927142.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQG
                     LSAWAVKAREYGIINHDVDNFAPRAFFSTLTNVNFDSPRIVGYARDAIAMREALKAQC
                     LSVDANAHCDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECAMEIGQMNFKVMSIL
                     DAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRS
                     IVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLVGGCDGARGERNYFTDFVTSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFFTPDLLAILNEKFGLRSVTTVEEDMKQLLSA"
     gene            25498..26466
                     /gene="hcr"
                     /locus_tag="OPY25_001499"
     CDS             25498..26466
                     /gene="hcr"
                     /locus_tag="OPY25_001499"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HCS0927143.1"
                     /translation="MTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYAL
                     VSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDGTGSQWLTHDIKRGDYIWLSDAMG
                     DFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADEW
                     RQYPVTLVAENHATEGFIAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALG
                     VTHFFKEKFFTPVAETATSGLKFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAG
                     VCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDLVLA"
     gene            26624..28342
                     /gene="poxB"
                     /locus_tag="OPY25_001500"
     CDS             26624..28342
                     /gene="poxB"
                     /locus_tag="OPY25_001500"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HCS0927144.1"
                     /translation="MKQTVAAFIAKTLEQAGVKQIWGVTGDSLNGLSDSLNRMGTIEW
                     MPTRHEEVAAFAAGAQAQLTGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPENAVTHWYHAPHPVVTPAEEELKKLAQLLRYSSNIALMCGSGCAGAHEE
                     LVALAAKLKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLILLGTQF
                     PYRAFYPSDAKIIQIDINPGSIGAHSKVDMALVGDIKATLRALLPLVEEKSNRKFLDK
                     ALEHYRDARKGLDDLAKLSDKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATAPGRQVIAMCGDGGFSMLMGDFLSVVQMK
                     LPIKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKAADVD
                     GALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            28381..29382
                     /gene="ltaE"
                     /locus_tag="OPY25_001501"
     CDS             28381..29382
                     /gene="ltaE"
                     /locus_tag="OPY25_001501"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HCS0927145.1"
                     /translation="MIDLRSDTVTRPGRAMLEAMMTAPVGDDVYGDAPTVNALQRYAA
                     DLSGKEAALFLPTGTQANLVALLSHCERGEEYIVGQGAHNYLYEAGGAAVLGSIQPQP
                     IDAAADGTLPLENVAAKIKADDIHFARTRLLSLENTHNGKVLPRAYLKDAWTFTRERG
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAT
                     RWRKMVGGGMRQAGILAAAGLYALKHNVARLQEDHDNAAWLAQQLREAGADVMRHETN
                     MLFVRVGEAQAAALGGYLRERNILINAAPIVRLVTHLDVSREQLADVVAHWRAFLAR"
     gene            29393..30826
                     /locus_tag="OPY25_001502"
     CDS             29393..30826
                     /locus_tag="OPY25_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HCS0927146.1"
                     /translation="MAQRILVLGASGYIGQHLVFALSQQGHQVRAAARRVERLEKHRL
                     ANVSCHKVDLHWPENLPALLRDIDTVYYLVHGMGEGGDFIAHERQAALNVRDALRQTP
                     VKQLIFLSSLQAPAHEQSDHLRARQLTADTLRDAGVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPILTPPRWVRSRTTPIALENLLYYLVGLLEHPAHEHRILEAAGPQVLSYQQQ
                     FERFMAVSGKRRPLIPVPFPTRWISVWFLNVITSVPPTTAKALIQGLRHDLLADDAAL
                     KKLIPQTLITFDDAVRRTLKEEEKLVNSSDWGYDALAFARWRPEYGYFPKQAGFTAQT
                     PASLSALWQVVNRLGGKEGYFFGNILWQTRAAMDRLVGHKLAKGRPSHTLLKPGDTVD
                     SWKVIIVEPEKQLTLLFGMKAPGLGRLSFTLHDKGRYREIDVRAWWHPHGMPGLIYWL
                     LMIPAHLFIFRGMARRIARLAEQITEK"
     gene            30922..31935
                     /locus_tag="OPY25_001503"
     CDS             30922..31935
                     /locus_tag="OPY25_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCS0927147.1"
                     /translation="MKVLVTGATSGLGRNAVEFLRNKGISVRATGRNEAMGKLLEKMG
                     AEFVHADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAAGEEVINLLAQANPQ
                     TRFTVLRPQSLFGPHDKVFIPRLAHMMHHYGSVLLPHGGSALVDMTYYENAIHAMWLA
                     SQPGCDHLPSGRAYNITNGENRTLRSIVQKLIDELTIDCRIRSVPYPMLDMIARSMER
                     FGKKSAKEPPLTHYGVSKLNFDFTLDTTRAQDELGYQPIVTLDEGIERTAAWLRDHGN
                     LPR"
     gene            complement(31932..32762)
                     /locus_tag="OPY25_001504"
     CDS             complement(31932..32762)
                     /locus_tag="OPY25_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCS0927148.1"
                     /translation="MKALLWLVGLALLLTGCASEKGIIDKEGYQLDTRHRAQAAYPRI
                     KVLVIHYTAENFDVSLATLTGRNVSSHYLIPATPPLYGGKPRIWQLVPEQDQAWHAGV
                     SFWRGATRLNDTSIGIELENRGWRMSGGVKSFAPFESAQIQALIPLAKDIIARYDIKP
                     QNVVAHADIAPQRKDDPGPRFPWRELAAQGIGAWPDAQRVAFYLAGRAPYTPVDTATV
                     LALLSRYGYEVKADMTAREQQRVIMAFQMHFRPAQWNGIADAETQAIAEALLEKYGQD
                     "
     gene            complement(32759..33082)
                     /locus_tag="OPY25_001505"
     CDS             complement(32759..33082)
                     /locus_tag="OPY25_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCS0927149.1"
                     /translation="MQFSTTPTLEGQSIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFQELGEQAKALGADAVVGIDIDYETVGKDGSMLMVSVSGTA
                     VKTRR"
     gene            33210..33725
                     /locus_tag="OPY25_001506"
     CDS             33210..33725
                     /locus_tag="OPY25_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0927150.1"
                     /translation="MRYSKLSLLIPCALLLSACTTVTPAYKDNGPRIGACVEGGPDSV
                     AQQFYDYRIQHHSNDIAALRPYLSDNLAKLLTDASRDTEHRQLMSGDMFSSRATLPDS
                     ANVASASTIPNRDARNIPLRVALKQGDQSWQDEVLMIHEGSCWVIDDVRYLGGDVHAP
                     AGTLRQSIENR"
     gene            33954..34682
                     /gene="artP"
                     /locus_tag="OPY25_001507"
     CDS             33954..34682
                     /gene="artP"
                     /locus_tag="OPY25_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HCS0927151.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPEGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLTIAGNHFDFTKTPSDKAIRELRQNVGMVFQQYNLWPHLTVVQN
                     LIEAPCRVLGLTKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIHELAETNITQVIVTHEVEVARKTASRVIYMENGH
                     IVEHGDAGCFAHPQTEAFKNYLSH"
     gene            34700..35431
                     /gene="artJ"
                     /locus_tag="OPY25_001508"
     CDS             34700..35431
                     /gene="artJ"
                     /locus_tag="OPY25_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HCS0927152.1"
                     /translation="MKKVLIAALIAGFSLSATAAQTIRFATEASYPPFESMDANNKIV
                     GFDVDLANALCKEIDASCTFTNQAFDSLIPSLKFRRFDAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDAVFGDTAVVTEWLKANPKLAPVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KFNTALEKVKKDGTYETIYNKWFQK"
     gene            35438..36154
                     /gene="artQ"
                     /locus_tag="OPY25_001509"
     CDS             35438..36154
                     /gene="artQ"
                     /locus_tag="OPY25_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HCS0927153.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIIGLALAMFFAVWESVKWRPIA
                     WIGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTLHLGFTQIPVQMEIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPSGQWESGQALGLSKTAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFNWYIIAAAIYLVITLI
                     SQYILKRIDLRATRFERRPD"
     gene            36154..36822
                     /gene="artM"
                     /locus_tag="OPY25_001510"
     CDS             36154..36822
                     /gene="artM"
                     /locus_tag="OPY25_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HCS0927154.1"
                     /translation="MLEYLPELLKGLYTSLTLTVASIAVALVLALVFTIILTLKTPFV
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPLLWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCGALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVVVFGAAGVIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            37059..37790
                     /gene="artJ"
                     /locus_tag="OPY25_001511"
     CDS             37059..37790
                     /gene="artJ"
                     /locus_tag="OPY25_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HCS0927155.1"
                     /translation="MKKLVLAALLASFATGSIAAEKINFGVSATYPPFESLDASNKIV
                     GFDIDLATALCKQMQAECTFTNHAFDSLIPALKFRKYDAVISGMDITPERSKQVAFSN
                     PYYANSALVIAKKDTYKTFTDLKGKRIGMENGTTHQKYLQDKHPEVKTVAYDSYQNAI
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGPATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKISDQWFPQ"
     gene            complement(38009..39496)
                     /locus_tag="OPY25_001512"
     CDS             complement(38009..39496)
                     /locus_tag="OPY25_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HCS0927156.1"
                     /translation="MKAIILLFDSLNKNYLPPYGDLLTKAPNFQRLAAHAATFDNSYV
                     GSMPCMPARRELHTGRYNFLHREWGPLEPFDDSMPELLKKAGIYTHLISDHLHYWEDG
                     GGNYHNRYSSWDVVRGQEGDHWKASVGEPPIPEVLRVPQKQTGGGVSGLWRHDWANRE
                     YIQQEADFPQTKVFDAGCDFIHKNHAEDNWLLQVETFDPHEPFYTTEEYLSLYDDEWQ
                     GSHYDWPRGKVSESEEAIAHIRCRYRALVSMCDRNLGRILDLMDEHDLWRDTMLIVGT
                     DHGFLLGEHGWWAKNQMPYYNEVANNPLFIWDPRSAVCGARRQSLVQMIDWAPTLLDY
                     FQQPIPADMQGQPLAKVIASDEPVREGALFGVFSGHVNVTDGRYVYMRAAQPGREHDI
                     ANYTLMPIKMNARYDVDELGKLSLAPPFKFTKGLQVLRIPAREKYKGVNSFGHLLFDL
                     RDDPQQQHPIHDEAIEARMINLLIRLMKENDAPAEQYRRLGLDVV"
     gene            complement(39506..39826)
                     /locus_tag="OPY25_001513"
     CDS             complement(39506..39826)
                     /locus_tag="OPY25_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCS0927157.1"
                     /translation="MKDSVNILFVCGYGVGSSVMLQTVVKKALAKYDFSFDMEHTAAG
                     EVGGFTDWADIYAISKKLLDVVSLDPKHGQYLIPIENIMDSESIGKQIYDVVEKNFPH
                     LLNK"
     gene            complement(39858..41201)
                     /locus_tag="OPY25_001514"
     CDS             complement(39858..41201)
                     /locus_tag="OPY25_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCS0927158.1"
                     /translation="MEGVQTMFAKFIDVIQTFLTEPAILIGILVGVGYALDKKTPIKI
                     ITGMISAMVGLMMVLFGGFQFSATFKPVAEAVSKAYGVHGYLMDSYAMKAATQIALGD
                     NFGYVGYVFVLAFFTNLILVLFGRYTGAKGIFLTGNTGVSHSQAVLWLIVFWLGFGWV
                     QSIVIAGVLTGVFWAFSTTLIVKPIAKVTNNAGFTIAHNQMLGLWFFSKFAHKFGDPE
                     KHDAENLKLPGWLAIFNHNVTAIAIVMTLFVGGFLLATGIDNVQLMAKGKPWYIYIIN
                     LGLQFSMYMVILLQGVRMMVGEINGSFKGWQDRFIPNAIPAVDVAALLPFSPNAATLG
                     FVFCTFGTIFSMGILLLIHSPIMVLPGFVPLFFSGGPIGVLANRMGGYRSVIICTFLL
                     GIIQTFGTVWAIPLTGLAKEGVGWTGIFDWATLWPAICELLKFIASTFHLGPYSI"
BASE COUNT         9529 a        11454 c        10577 g         9735 t
ORIGIN      
        1 tgctgcggct gctgatactg tggctgcggc gctaccggct gctgatactg cggctgcggc
       61 gctacaggtt gctgaacagg cgttgactcg ggcatgacac ccggcgtgaa cagcggttcg
      121 tgcggacctt catcaaccaa tactttcatt ggcgagaaat ccagatcgtc cagtgagaac
      181 ggctgcgcgc cagcgggttg ctcgccggaa tagcgctgct gttgcgaagc ggcaaactgg
      241 cgggctaatt cagcttccgc agcggtatcg tcatcttctg cctgttgagt atcatgctga
      301 tacgtctcac cataacgatg ctgctgcgac tgcgcaaact gacgggctaa ctcgtcctga
      361 tgcattgcat ctatttcttc atcggttagc tgcgcgcccg tctcgtactg attgcgctcc
      421 gcctcgcggg ctttttcttc agcaatcctc tgtgacggca gcttaatacc gtacgatgcc
      481 agttcccgtc gggtcggcac gcgaacgcgg ttcggacgcg gcagttgcgg accaatcccc
      541 tctttcacct gcggacgcgg cgcgccgccg gtagccagac taaatgcagg cgcagcggcc
      601 gcggcgcctg ctgccagggc gccactctta atacctgtgt caagcgacgc ggcggcggct
      661 accgcttcca ctggcggtat ggacggcgcg acagataccg taggtttgac cggcacgttc
      721 tcttttaccg gctccggaat cggttgatac catgccgcca gttgttcgcg ctcacgggcg
      781 cgtttctctt ccacctcttc aaaatagtaa agcggagggc gagcgggcct ggtctcttct
      841 atgccaggtt caggctcggt ggcaaccggc tgttcgataa ccggcggcgg catgtgggaa
      901 ggttcagccg ctatcggctc cggctgccag tgttgttcgg catccggcgc ctgccattgc
      961 ggctgtgttt cctgcggcgc aagagagtca tattctgctg cggtcgctgg cgtcgcggcg
     1021 tattgcggcg cggaagcgac aggcacaggt tgctgccacg gcgcactttg cgcctcctgc
     1081 ggttgagcat attgcggatg cggctgatac ccctccggcg caggcgcgat aaccggttcg
     1141 ccggtttgcg gccccggtac gggctgccac tccacggtcg gttgcgcgac aaccggctca
     1201 gcccccggca tgggcggcgt ttgcattatg ggatcggcgg acgctgccca cgtctgggtg
     1261 acggcagttg cggccgcagc ggcggcgacc ggttcggtga cagaatggcc gtttaacagc
     1321 ggatcatatt catcatattc cgactgcgtc gcacggttgc ccgaaaacag aacgtcgtcg
     1381 ggatcggcag cgacgccgcg cgcgctatac tgaatgtcct cgtcatcatc catccgtttg
     1441 ccggaaaaga gcgcggcatc ggtctgacgg ccccgtggat tgctgaattt ttcagccagt
     1501 cgcttacgac gcgccaacgc gccgcgcaaa atacgcgccc ggcgagattc acgctgcacg
     1561 ccatcggttt cttcatcgta ttcgtcatca tactcttcgt cgtcaaccca cgtatcatca
     1621 cgccgggtac ggttgctggc gaaggtcagt atattaagca gccagccgcc taatttttcg
     1681 gcgatactaa cccaggacca gccggtaaag agcgtcagcc cggcagccca aatacagaga
     1741 agcattatcg ttccgccgct actatgcaac aacggctgca gcgtggtgct taacaggctg
     1801 ccaattacgc cgccggaggc gaaataccag atatcgtcgg cattaatggc cgccagaccg
     1861 caggaagtga gaatcagcgc cagcacgcca ataaggcgta gcgacacagc aaaatagtcg
     1921 atgtaatcat ccgtagactg atgacgccac gcaaaccaac acccgccgac aataatgaca
     1981 gggatagtgt aggccattac gccaaaaata aagaacagtg tatcggccag ccacgcgccc
     2041 ggcgcgccgc ctaaattatg gatgggttca tgccaggcgg tttgcgacca actggggtcc
     2101 gaagggttaa agctcaacaa ggccgccatc aaccagacgg caaaaagggc aataagtatc
     2161 aacaacgctt ccagaagtcg gcgcccgctg cttaacttcg tcaatgtgac gtctttgtct
     2221 tcagtatatt cctggctcaa aaaaggctct ccaggttcca ggcttttccc gcccgatgct
     2281 aaaacggaca acagcaccgg gttgccccgg cactgttgct gtatggatta acaggagtgt
     2341 aatcaaacta cggcgatttt gcacctgttc cgtgttagcg tgtcttaata accagacgat
     2401 tactctgttt tacctcttcc atcactacgt aagttcgggt gtcgttcaca cctggcaagc
     2461 gcagcaacgt ctctcccaat agttttcgat acgctgacat atccggtaca cgggttttca
     2521 acaggtagtc gaaatcgccg gaaaccaaat gacactcctg aatctcttca agctttttca
     2581 cggcggcatt aaactgttca aacacatccg gcgcgccgcg atttaaggta atctcaacga
     2641 ataccagaag tgacgcatcc agataatgcg ggttcaacag cgccgtatag ccctggataa
     2701 acccctgtcg ctccagccga cgcacacgct caaggcaagg tgtcggcgaa agtcctactc
     2761 gtttagaaag ctcgacgttg gaaatacgcc catccttttg cagttcatta agaatgttac
     2821 gatcgatacg gtcgagatct ttgccagggc gcttcttgct atctaccatt attattgtct
     2881 ctctgtattc cttccctact cctgcctgac tctactcaca tcactgttca gagtcgctgc
     2941 ccatcacaat agaccgaaac ccagagggat taacggcgtg caatgcctgg tctatggtga
     3001 gaagaccgtt gcctcgcggc agctatcgac atcacgaatg gcgtctgtcc acgccatgcg
     3061 tagatttcac tagcccggta aacatggtat ttacatgcat gattatgcag cacatacata
     3121 acacagtttt tttcttcctc gaatgttttc gcaaaacagc aggtgattgt caaagcaaaa
     3181 catcgatttt tagtacaaca tgccagttat tcattagaga gggcggtaaa ctgtcatttc
     3241 gtcaccttat aagttaccga ttttaattaa agtttgtgat gataacgtcg ctgccgcggt
     3301 cgttcatcgg ttcatgctat tacacatatt gttaacaaaa tcgttatgct ctttttttac
     3361 gtctgtaaat tctctacaat tctgctcatt gtctgccaac aactatgggg atctcatggg
     3421 cacgaccaaa cacagtaagc tgcttattct gggctcagga ccggcgggat ataccgcggc
     3481 ggtgtatgcc gcgcgcgcaa atttacagcc agtacttatt accggtatgg aaaaaggcgg
     3541 tcaactgact accacgacgg aagtggaaaa ctggcccggc gatccaaacg atttgaccgg
     3601 cccgctgctg atggaacgca tgcatgaaca tgcggcaaaa tttgaaaccg agataatttt
     3661 tgatcacatc aacaacgtgg atctgcaaaa tcgtccgttc cgtctgacag gtgacagcgc
     3721 agagtacact tgtgatgcgt tgatcattgc gaccggcgct tccgcgcgct atctggggct
     3781 gccatcggaa gaagccttta aagggcgcgg cgtttccgcc tgcgcaacct gcgacggttt
     3841 cttctaccgc aatcagaaag tggcggtgat cggcggcggc aacaccgcag ttgaagaagc
     3901 gctttatctg tccaacatcg cttcggaagt gcaccttatc catcgccgtg acggtttccg
     3961 cgctgaaaaa atcctcatta agcgcctgat ggataaagtc gaaaatggca atatcatcct
     4021 gcacaccaac cggacgctgg aagaagtgac cggcgatcag atgggcgtta ctggtctgcg
     4081 tcttcgcgac acgcagcaga gcgataatat cgagacgctg gacatcgccg gacttttcgt
     4141 agccatcggt catagcccaa acacggcact cttcgaaggc cagcttgagc tggaaaatgg
     4201 ttatatcaaa gttcagtccg gcacccatgg caacgccaca caaaccagca tccctggcgt
     4261 attcgcggcg ggtgacgtta tggatcatat ttaccgtcag gcgatcacct ctgcaggtac
     4321 gggctgtatg gcggcgctgg atgccgaacg ctatctcgat ggtctggccg acgcgagcaa
     4381 atagttttta caaatcagta acaaaagtaa aaaaggcgac tataagtcgc ctttattttt
     4441 gcgtcgttgt aacattgccc tgcctgaaat tccaataact cacctgctaa gcgtgcaatg
     4501 aataaaaccc gtcaaaaaga gctgacccgc tggttaaaac agcaaagcgt aatctcccaa
     4561 cggtggttga atatttcccg cctgttgggg ttcatgagtg gcgtattaat tgtcgctcag
     4621 gcctggatca tggcgcgtat cctgcaacat atgatcatgg agaacattcc acgggaagcg
     4681 ctgttgctcc cttttatcct gctgatactg atctttgtcc tccgcgcctg ggtggtgtgg
     4741 ttgcgcgagc gcgtcggttt tcatgccgga cagcatattc gctttgagat ccgccgtcag
     4801 gtgttggatc gtctgcagca agccggccca gcctggattc agggcaagcc cgccggtagc
     4861 tgggcgacgc tggtgttgga gcagattgac gatatgcatg actattatgc gcgctatctg
     4921 ccgcaaatgg cgcttgccgt ttgcgtaccg ctcttaatcg tggcggcgat tttcccgtca
     4981 aactgggcgg cggcgctgat tctgctgggc actgccccgc tcattcccct atttatggcg
     5041 atggtgggga tgggcgcggc tgacgccaac cgccgcaatt tcctggcgct tgcccggcta
     5101 agcggccatt ttcttgaccg tctgcgcggg atggaaacgc tgcgaatttt cggtcgtgga
     5161 gaagcggaaa ccgagagcat tcgcgcagca tcgcaggatt ttcgtcagcg cacgatggaa
     5221 gtactgcgcc tcgccttttt atcttccggc gtgctggaat ttttcacctc gctttctatt
     5281 gcgctggtcg ccgtttattt tggcttctct tacctgggcg agctgaactt tggtcattac
     5341 ggtaccggtg tgacgctcgc cgccgggttc ctcgccttga tcctcgcgcc ggagtttttc
     5401 cagccattac gcgacctcgg cacgttttat catgctaagg cgcaggcggt tggcgcggcg
     5461 gatagtctga agacatttct ggaaacaccc cttgcccacc cggcgcgcgg cgaagttgag
     5521 ctggcggaaa acgaacctgt aaccattgac gcagtcaatc ttattatcac ctcgccagaa
     5581 ggcaaaacgc ttgccgggcc gctgaatttc tcattagcgg caggagaacg cgccgtcctg
     5641 gtaggacgca gcggttccgg taaaagctct ctgttgaatg tattatccgg ttttctctcc
     5701 tatcagggat ctttgcgtat taatggtgtc gaacttcgcg atctctcgcc ggaatcctgg
     5761 cgccagcatc tctcctgggt cggacaaaac ccgcaattac ctgcggcgac gctacgcgaa
     5821 aatgtattac tggcgcgccc ggacgccagc gagcaggaac tttatgccgc gcttgacgcc
     5881 gcatgggtaa gcgaattttt accgctgctg ccgcagggag tagacacccc gctcggcaat
     5941 catgccagca gactttccgt cggccaggca cagcgtgtag cggtcgcccg cgcgctactt
     6001 aatccctctc aactgctact gctggatgaa ccggcggcaa gcctggacgc tcacagcgag
     6061 caacgcgtca tgcaggcatt aaaagcggcg tcaaaacgcc agaccacatt aatggtgacg
     6121 catcagttgg aagatctcgc cgactgggac gctatctggg ttatgcaaga tggcgcgatt
     6181 gtcgaacaag gcagctatgc cgaactcagc gccgccaacg gcgcttttgc gacgttattg
     6241 gctcaccgtc aggaggatat ttaaatgcgc gcgctactcc cttatctgac gctttataaa
     6301 cgccacaaat ggatgctaac gctgggaatt gcgctggcaa tcctgaccct gcttgccagt
     6361 atcgggctgc tgacgctttc cggctggttc ctgtccgcgt ccgctatcgc aggcttcgcg
     6421 ggaatttaca gttttaacta tatgctcccg gcggccggcg tgcgcggcgc ggccattacc
     6481 cgtaccgctg gtcgttattt tgaacgtctg gtaagtcatg acgccacgtt ccgcgtgctg
     6541 caacatctgc gtatttatac cttcagcaaa cttctaccgc tctcccccgc gggtctggcg
     6601 cgatatcagc aaggtgaact gctgaaccgc atcgttgccg acgtcgacac gctggatcat
     6661 ctctatttgc gcgtcatctc cccgctggtc ggtgcttttg tagtgattat gattgtcacc
     6721 ctggggctta gcgttctcga cgtgacgctg gcgatcacgc tgggcggcat tatgctgttg
     6781 acgctgttta ttatgccgcc ggtgttttat cgcgccggca aaaataccag ccaaaatctg
     6841 acgcatctac gcggtcagta tcgccagcag ctcacgtcat ggttacaggg ccaggcggaa
     6901 ctcaccattt ttggcgccag caaacgctat cgggcgcaaa tggaagccac cgaattacaa
     6961 tggcatgagg cccaacgccg acagtctgaa ctcaccgcct tatcgcaggc gttaatgctg
     7021 ctgattggcg cgctggcggt gatgttaatg ttgtggatgg cctccggcgg cgttggcggc
     7081 aatatgcagc ccggcgcgct catcgcgctg tttgtcttct gcgcgctggc ggctttcgag
     7141 gcgcttgcgc ccgttaccgg cgcattccaa catctggggc aggttatcgc ctctgcgctt
     7201 cgtatcactg aattaacgga gcaaaaaccg gaggtgacct ttccacaggc agaaactccc
     7261 gcgccggaaa aggtcacact caccctgcgg gacgtttcgt ttcgttatcc cgaccagccg
     7321 attaatgcgc tcaatgccct ctcattacag gctaatcctg gcgagcatgt cgctattctg
     7381 gggcgtaccg gctgcggaaa atcaacgctg ttgcagctac tcacccgcgc ctgggacccg
     7441 caacaaggcg aaattctgct caacgatctt ccgctatcct cgctgagcga atccgcctta
     7501 cgccggacta tcagcgtggt gccgcagcgt gtccacctgt tcagcgccac gctgcgtgat
     7561 aatttattac tggcggcgcc caatgccagc gacgaagccc tttccgacat gctgcgtcgc
     7621 gtcggcctcg aaaatctgct cgaagatagt gggcttaata gctggctcgg cgaaggcggt
     7681 cgtctgctat ccggcggcga acttcgtcgc ctggccatcg cccgcgcgct gttgcacgat
     7741 gccccgttga tgctgttgga tgagcctact gaggggctgg atgcgaccac cgagagcgaa
     7801 atgctggaat tacttgccga tgtgatgcgc gaaaaaaccg tcctgatagt gactcaccgt
     7861 ttgcgcggcc tggcccgttt tgatcaaatc atcgtaatgg acgacgggcg catcattgag
     7921 cgaggcactc atgcagaatt gttagccgga caagggcgct attatcagtt taaacaacgt
     7981 ctgtaagcta ttattgaacg atccgacttg cgtactggag tttcgccgtc atgcgtctgg
     8041 ttcagctttc ccgacattct atcgccttcc cttcgccgga aggcgcttta cgcgagccta
     8101 acggtttact ggcactgggc ggcgatctca gccctgcccg gttgttaatg gcctaccagc
     8161 acgggatttt cccgtggttt tcgccgggcg acccgattct gtggtggtcg cccgatccgc
     8221 gcgccgtgct gtggcctgaa aagtttcacc tcagtcgcag catgaagcgc tttcacaacg
     8281 catcccctta ccgcgtgacg ctcaattacg ctttcgaccg ggtcattgat ggatgcgcca
     8341 atcaccgtga cgaaggcacc tggataacgc gtggtattga ggaagcctat cgccgattac
     8401 atgaattggg ccacgcgcac tccattgaag tgtggcgcga tcgggaactg gtcggcggga
     8461 tgtatggcgt ctcgcagggg gcgctatttt gcggcgaatc gatgtttagc cgccaggaga
     8521 atgcctctaa aaccgcactg ctggtttttt gcgctgaatt tacccgccac ggcggtaaac
     8581 ttattgattg tcaggtactt aatagtcata ccgcctcgct cggtgccatt gaaattccac
     8641 gtcgtgacta cctcgatcac ctcgcggcct tacgccaaca gccgctggcc tcccgttttt
     8701 gggtgccgcg gacattattt ttgccccgga agtgaatgtt ttcggcacat tttttattgg
     8761 ggtgttataa ttgctgccgc agaattggtt tagctcatta tcacgcagcc cgttgtcagg
     8821 taacgcccat cgtttatttc accgttccct tatatgttgc gcttatgtcg atacatcagg
     8881 cggtagtatc agggaaaagg tgtataacgc ggcgttgtcg tgtgtcgcgg aatcatgtgc
     8941 taaacctggt ttgctgtgtt ttaaacgcac aaatctttac ttatcaaaag aagttcggca
     9001 ttatcttgcc ggttcaaatt atggtagtga taccccagag gattagatgg ccaaagaaga
     9061 caatattgaa atgcaaggta ccgttctcga aacgttacct aataccatgt tccgcgtaga
     9121 gttagaaaac ggtcacgtgg ttactgcaca catctccggt aaaatgcgta agaattacat
     9181 ccgcatcctg acgggcgaca aagtgaccgt tgagctgacc ccgtacgacc tgagcaaagg
     9241 ccgcattgtc ttccgtagtc gctaattgtc tcctcacgcc ctgaagggcg gctggataaa
     9301 aggtcggttt aaccggcctt ttttgcgtcc attaagtcga tgaatgacga gcaggttact
     9361 cttccaccat ccgcgcatac tcttccgtca aaaaatcgac caacgcacgt acggaaggta
     9421 atagccctcg ccgggatggg aacacagcat gaataacctc ccgccggggc tcccactctt
     9481 ccagcaccgc gaccagttca ccggcggcca gttgttcttt caccattaag acaggtaact
     9541 gcacaagccc cacgcccgcc atcgccgcct cgcgtagcgc caacatgtct gtagtaatca
     9601 tacgcggggt aaaatggact tccgcacgcg cgccctgcgg gccgtaaagt tcccagcggt
     9661 ggatatgctt gccggatgca agacttagcc ctggccaatg gctcaactcc gccggcgcgg
     9721 aagggattcc catccgtgcg atgagatccg ggctggcaaa caggcgatgc cctctgtcag
     9781 ccaggacgcg catcaccagg tcgctatctt caaacgggcg cggcctgacg cgaatcgcca
     9841 catccacccc ctcccctacg acgtccaccc gacgattggt cgcttcaagc tgtagcgaaa
     9901 catcaggata acgcgccata aacttcgcca gcattgggcc gatgtgtaca tgcagcagcg
     9961 tcaccgggca ggttagcttc acgataccgc gaggctctac ctgcaatgcg gcaatggcat
    10021 cctgcgccgc ctgagcttcc accagcatcg ctttacagtg ctcatagaat gtttgcccca
    10081 cttcggtaac gttaaactgc cgggtggttc gctgaatcaa tcgcacgccc agccgttcct
    10141 ccagttgcgc aatacgccgg ctcagttttg attttggttc atcaagcgca cgccccgccg
    10201 cggcaaaccc accctcttcg accacatgca caaaccacgc aaaatcattg agatccgttt
    10261 ttatcattac attgtcctat taatggaacg gtatgagcca ttttacccac taccgaacat
    10321 tttgtcatga atataagctt attcacatca agacaacgcc actgaggaga acaccatgaa
    10381 acagattaca ggcgtctata ccgcacctcg cccgcactgg gttggcgatg gatttccggt
    10441 tcgttcactc ttttcttatc agtcacatgc gcagcagttg aatccattcc tgctgctgga
    10501 ttatgccggg ccgcacacct ttacgccggg taatgaaaaa cgcggcgttg gggagcatcc
    10561 acaccgcggt ttcgagaccg tgacgattgt ttatagtggc gaagtcgagc atcgggactc
    10621 taccggtcgc ggcggcgtta tcggcccggg cgacgttcag tggatgagcg caggcgcagg
    10681 cattttgcat gaagagttcc actccgacgc gtttacccgt cggggcggcg aactggaaat
    10741 gatgcagttg tgggttaacc ttcccatgaa ggacaaaatg accaccccgg gttatcaaag
    10801 cattacccac gatgttatcc cgaccgttac gttgccggat gacgccggag tcgtgcgggt
    10861 catcgcaggg cgttatgaag agacaaaagg cccggcgcac actttctcgc cgctcaatgt
    10921 ctgggatatg cgcctgcaac gcaatcgcca gcttacattg gcacagccgg aaggatggag
    10981 cgccgcgctg gtggtactga aaggcaatat cacggtgaac ggcacgacgc cggccaacga
    11041 agcgcaactg gtggtattga gccagcaagg gaaaacgctg caccttgagg ccagcagcga
    11101 cgccagcgta ttgctgttat caggcgagcc gctgaatgaa ccgattgtgg gttacggccc
    11161 atttgttatg aacacgaaac aagagatcgc agaagcagtc cgcgatttca actccggccg
    11221 ttttggccaa atctgaaaac atgaaggaga acacgatgtc aagtcctgct agttttaatg
    11281 gtttgcgccc ggtaattgat gttaacgatt ccgtgatgct tttaatcgat catcaaagcg
    11341 gtcttttcca gaccgtaggc gatatgccaa tgccggaatt acgcgctcgc gccgcggcgt
    11401 tggcgaagat ggcgacgtta gcgaaaatgc cggtcattac cacggcatcc gtaccgcaag
    11461 gtccgaacgg cccgctgatc ccggagatcc acgctaatgc gccacatgca cagtacattg
    11521 cgcgcaaagg tgaaattaac gcctgggata acgaagattt cgttaaggcg gtaaaagcga
    11581 cgggtcgtaa gacgctgatc attgccggga cgattaccag cgtgtgcatg gcattcccgg
    11641 ccattagcgc ggtagcagaa ggttataagg tatttgccgt gatcgacgca tccggtacct
    11701 acagtaagat ggcgcaggag atcaccctgg cgcgtatcgt acaggctggc gtcgtaccga
    11761 tggatactgc cgcagttgcc tctgagctgc aaggcacctg gaaccgtgaa gacgcagccg
    11821 cgtgggccga cgtttatact caggtattcc cggcctatca actgctgata gaaagctaca
    11881 gcaaagcgca ggatgtggtg aaaaacaacg aaatgttgga ttcacagcgc taatttgcct
    11941 ccccgcgcca gtttgggcgg ggattatgtc tattgcatga gcaaacgaca gtgaatatgt
    12001 aaattctgct tgaccgtttt agcgcaactc cctatagtag cgccccgttg ccccccaagc
    12061 ggtcaggcag caatacaata tggtgaggtg tccgagtggc tgaaggagca cgcctggaaa
    12121 gtgtgtatac ggcaacgtat cgggggttcg aatccccccc tcaccgccat atttaagttg
    12181 agagcctgta cagaagtacg ggctttttgc ttatatgtat cccccaaacc aaggggggat
    12241 gagaaccacc gaccggggtt cgacaactgg cgcagccagt tggacagacc gggcgcgcag
    12301 cgaacgggct gccccgaagg ggcgagcaaa gcgagtcaat ccccccctca ccgccatatt
    12361 caagaaagag ctcgtacgaa agtacgggct tttgtatcta aacttcttgt ttttactgtg
    12421 attttcctga tgaaaggttt gtttttggac ctttggttgc tacaccaaac ttactataga
    12481 ttgtgtaaaa cagccctact tccctacctg aaacgcttta gaaaagtttg cataagtatc
    12541 tctcggtagt aaaaaagcac cgagttcctc tgtctgatgc tgctgttgat ttgttaaaag
    12601 atttaccacg attaaaagat aacaatcatg tattccctgc ccctcgcgct gaaacacttt
    12661 ctgatatgtc gttattggct gtattgaaac gaatgggata tatcgactta acgcaacatg
    12721 gcttccgttc tactttccgt gagtgggctg gtgaagcaac ggattatcaa cgtgaggtta
    12781 ttgaacatgc gttggcgcac cagttggcag ataaggctga agcagcgtat cagcgtggga
    12841 cgttatggcc taaacgagtg gcgctgatgg atgactggac ggggtatagc actgccaaca
    12901 gctaagctac ctgtacgaaa gcattatcgt tgataacaac gtagaaagtg tgatgctaat
    12961 agcattcgct ttcgaaaatg tgataaggaa taatttcacg atgaactatt tcttatatga
    13021 ttattatcat ggtttgcaaa ttacataaac cactcaagga gaggttatgc ccggactgat
    13081 aggctactgg aagcaacttc ccaccaaaga tgaatatatt aaaaaacaca atatgagcaa
    13141 aatatcctgc tacagttgtg gtcacgagaa attcagcgat gttggtttga tacaggtatg
    13201 ggataatcac agaagaattc tttgtgctaa gtgtaagact actcttttca gagaagagga
    13261 ttagtttttt tggcattggt aacagcggct tcagcatccc ttttcacgca gcgggtcggg
    13321 ctttttttcg catttgaccc gtcgattacc ggatgatggc gcaatttaca agcgccttat
    13381 ccgcctaccg cgagcacaac accatcaggc taactattag ccggcataaa aaaaccgggc
    13441 gctaaggccc ggtttgtacg gcagtgaaac gaagattagt gcgcggcttc cggcttgtgc
    13501 ttttgcgcac tctggaagtc atacgtcaac gcatttttct ctttatccag cgcgacggtg
    13561 acctgtccgc cgtcaaccag cgatccaaac agcaactcat tggccagtgg ttttttcagg
    13621 ttatcctgga tcacacgtgc cattggtcgt gcgcccatcg cccggtcata gcccttttcc
    13681 gccagccagt cgcgcgcttc ctgactgact tccagggaga cgcctttctg atccaactga
    13741 gcctgcaact cgacgataaa cttatcgaca acctgatgaa tcacctcgcc agacagatga
    13801 tcgaaccaaa taatgttgtc gagacggtta cggaactcag gcgtaaacac tttcttgatc
    13861 tcgcccatcg catcggtact gttgtcctga tgaataagac caatagattt acgttcggtt
    13921 tctcgcacgc cggcgttggt ggtcatcacc agcaccacgt tgcggaaatc cgccttgcgg
    13981 ccgttgttat cggtcagcgt accgttatcc atcacctgca gcagcaggtt aaagacatcc
    14041 gggtgcgctt tttcgatctc atccagcaac agcaccgcat gaggatgctt aatcaccgca
    14101 tccgtcagca gcccgccctg gtcgaaaccg acgtatcccg gaggcgcgcc gatcagacgg
    14161 ctcaccgtat gacgctccat atattcggac atatcaaaac gcaacagctc aatacccagc
    14221 gcttttgaaa gctgtaccgt aacttcagtt ttccctacgc cagttgggcc ggcgaacaag
    14281 aatgagccga caggtttatg ctcatggccc aggcccgcac gactcatctt aatagcttcg
    14341 gtcagcgcct caatcgcgtt atcctggccg aagaccagca ttttcagacg atcgcccagg
    14401 ttcttcagcg tatcgcgatc gctctgcgag acgctctttt caggaattcg cgcaattcgc
    14461 gccactacgg actcaatatc cgccacgttg accgttttct tacgtttgct caccggcatc
    14521 agacgcgccc gagcgcccac ttcgtcaatc acgtcaatgg ctttatccgg cagatggcgg
    14581 tcattgatat attttaccgc cagctcgacc gccgcacgca ccgctttcgc ggtataacgc
    14641 acgtcgtggt gcgcttcgta cttaggtttc aagccgttga taatttgcac cgtctcttcc
    14701 accgaaggct cggtaatatc aattttctgg aaacggcgcg ctaatgcgcg gtctttctca
    14761 aaaatattgc tgaattcctg ataggtcgtt gagccgatca cccggatctt gccgctggaa
    14821 agcagcggtt taatcagatt tgccgcatcc acctgtccac ccgacgccgc gccagcgccg
    14881 ataatggtat ggatttcatc gataaacagg atgctgttgg tatcctgctc aagctgtttc
    14941 agcaacgcct taaaccgttt ttcaaaatcg ccgcggtatt tggtgcccgc cagcagcgaa
    15001 ccgatatcca gagagtaaat agtacaatcg gccatcactt ccggcacatc gccctgcacg
    15061 atacgccagg ccagcccttc ggcaatcgcc gttttgccga cgccggattc ccctaccagc
    15121 aacgggttat ttttacggcg acgacacaag acctggatcg cgcgttcaag ttctttttca
    15181 cgaccaatca gcggatcgat gccgcccacg cgagcaagtt ggttaagatt cgtcgtgaag
    15241 ttttccatac gttcctcccc gccagcttgt tcgtcgccag ctggctgatt gccgagatcg
    15301 gaagattggc tcggttcgtc ttttcgcgtc ccgtgagaaa taaagttcac gatatccaga
    15361 cggctcactt catgcttacg cagcagataa gccgcctgtg attcctgctc gctaaagata
    15421 gccaccagca cattcgcgcc agtcacttca ctacgcccgg aagactgaac gtggaagacg
    15481 gcacgttgca ggacacgctg gaaacttaac gtcggctgcg tatcacgctc ttcttcactg
    15541 gcaggcagta cgggtgtggt ttgttcaatg aaggcttcga gttcctgacg gagcgccacc
    15601 agatccacgg agcatgcttc cagcgcttcg cgagccgatg ggttgctgag cagcgccagc
    15661 aacagatgct cgacggtcat aaactcatga cggtgctcgc gcgctctggc gaaagccatg
    15721 tttaaactga gttccagttc ttgattgagc ataggcacct cccccaattt ttatacctgc
    15781 attcaggctt tttccagcgt acacagcaac ggatgctcgt tctcccttgc atacttgttc
    15841 accatcgcca ctttggtttc cgccacctcg gcggtaaaca cgccgcagat agctttgcct
    15901 tgatagtgaa ctgcaagcat caattgcgtt gcacgttcta catcataaga aaagaatttt
    15961 tgtaacacgt caataacaaa ctccatcgga gtgtagtcat cattgactaa tatcacttta
    16021 tacatagatg gcggttttag cgcgtcgcgc acgctatctt ccaccaactg gtcaaaatcc
    16081 agccaatcgt tcgtcttacc cattgtcagt cgtcattatc ggttacggtt gtcggcagga
    16141 aaatctgccg ctgaccagag tctatgcaca caatcaatct acctcaattg atagataact
    16201 aacatctatc agtaccatcc acgacatctg tcacattccc ggcaatagcg ttaactgctt
    16261 caaatttttg attcattttt acccgatccc ccctgcctga tgcttgacgc ctcgcctgat
    16321 ttctctaaat tgtaatgtcg agagttggtg aggttttgaa cagcccccac tccgtcaccg
    16381 gttcattcca tcttacttat ataagattta cgaaggatgt cgaagcatgg aaacgggtac
    16441 tgtaaagtgg ttcaacaatg ccaaagggtt tggtttcatc tgccctgaag gcggcggcga
    16501 ggatattttc gcccattatt ccaccattca aatggatggt tacagaacgc ttaaagccgg
    16561 acagtctgtc cggtttgatg tccaccaggg gccaaaaggc aatcacgcca gcgtcatcgt
    16621 gcccatcgaa gcagaggccg ttgcatagct cctctgtctc attgtgtaca tccagaaggc
    16681 aaaatgccag cccgatcggc tggcattttt atttaacgcc agtgcctggt ggcgacactg
    16741 ttgcatctta tcaggccgac aaatgacgtc agcaagatta ctctcttgcc agcgcatcca
    16801 ccgggtccag tcgcgccgcg tttctcgccg gtagccagcc aaacaatatc ccggtaaacg
    16861 tcgaacataa aaacgcgctc gccagcgctg tcagtgaaaa accgatctcc cagccgggca
    16921 ggaaaagctg tagcataaat gcgatgaaca tcgacaagct aatccccagc gctccaccaa
    16981 ccaggcaaac cagcaccgct tcaataagaa actgctgtag cacatcgctg gcgcgcgcgc
    17041 ctaccgccat acggatgccg atttcacgcg ttcgctcggt gacggaaacc agcataatat
    17101 tcataacgcc gatgccgccg acaaccagcg aaatgacggc caccagcgtc agaaataact
    17161 gaagagtata ggtggttttt tcagccgttt tcaggacgct gtccatattc caggtgaaga
    17221 agtctttttt accgtggcgt aaggtgagca ggcgggtaag ctgctgttca gcctgatcgc
    17281 tatcaacgcc atctttcaca cgaacggtga tcgagttaag ccatgactga cccattatgc
    17341 gatctgacat cgtgctatag ggcaaccaaa cttgcaacag attgctattg ccgtacatgg
    17401 acggtttctc ttccgccacg ccaataacaa taaccggcat attacccacc agcaccactt
    17461 ctcctacgac attcgcttta tttggaaata gctggcgtcg cgtgttggca tccaacacca
    17521 ccacctgcgc gcgatcctgt tgctgtacag cattgaaggt gttcccctcc ctaaaggaca
    17581 tgccgtaaac gttaaaataa tcgccactga cgccattagc atttacggca atatcaatat
    17641 tgccatagcg aagacgtaag ctctttgaaa cgctgggcgt cgcagagtta acccacggct
    17701 gtttctgaat agccaccaga tcgtcatatt tcagcgcctg tcgatactgc gggttgtcgt
    17761 cgccaaaatc tttgcctgga tgaatatcaa tcgtgttagt gcccatagcg cggatatccg
    17821 ccagtaccat ctgttttgcg gcgtcgccga ccaccacaat cgacaccacc gacgcaatac
    17881 cgataataat tcccagcatg gtcagtaaag tacgcatttt gttagcggcc atcgctaacc
    17941 acgccatcga cagcgcttcg cgaaagctgc tggcaaattg ccgccagccg ggagccgtat
    18001 taactacggc agcgtcaacg ccctgttcgc gtttcttttc ctgcgcgggc ggattatgga
    18061 caatcttgcc atcgtgaatt tcaataatcc gctccgcctg ggcggcaatc agcggatcgt
    18121 gcgtcacaat gatcaccgta tgtccgcgat cgcgcagttg gcgcaaaatc gccattacct
    18181 cttcgccgga atggctatcc agcgcgccgg tcggctcatc cgccagaatc acctgtccgc
    18241 cgttcatcag cgcgcgggca atactgacac gctgctgctg tccgccagaa agctgtgaag
    18301 gtggataatc gacgcgatcg cttaatccca gccgcaaaag caactctctg gcgcgcgcct
    18361 ggcgtttttt gcgttcaatg ccggcgtaga cggcggggat ttcaacattt tgcgctgccg
    18421 ttaaatgcga caacagatgg tagcgctgaa agataaagcc aaaatgctca cgccgcagct
    18481 gcgccagcgc gtccgggtcc agcgtcgaga cgtcccgccc cgccacccga taagtgccgc
    18541 tggtcggttt atccaggcac ccgaggatat tcatcagcgt tgattttcca gaaccggaaa
    18601 cgccgacgat cgccaccatc tccccggcgt ggatttgcag ggagatatct ttcaacaccg
    18661 ccacctgctc ttctccggag gggtagctgc ggctcacatt gcacagttca agcaatgccg
    18721 tcatggcgtc gctcctggcc tgctctcgcc gatgatcacc tcatcgcccg cttccagacc
    18781 tttaaccact tccacgtctg tatcgttacg ctcgccaatg accacttcgc gctcacgttt
    18841 ttcgccgtta cgcaacagcg ccactttata acgattaccg cccaccggct cgccaagcgc
    18901 ggcgagagga ataatcagca catttttgac atccatgagt tgaatataaa cctgtgcggt
    18961 catatcaaga cgcaagattc ttttgggatt cggcacttca aaccgggcgt aataaaaaat
    19021 agcgtcgttg atcttttccg gcgtcggcag aatatctttt aaaacgcctt catagcgcgt
    19081 ttgcggatcg cctgcaatgg tgaaccatgc tttctgcccc gcccgaagat ggatcacgtc
    19141 cgcttccgag acctgcgctt ttaccagcat ggtgctcata tccgccagcg tcagaatatt
    19201 gggcgcctgc tgagctgcaa tcaccgtttg tccttgcagg gtagtgattt gcgtcacttc
    19261 ccccgccatg ggggcgacaa tacgggtata ttccaggttg gttttcgcgg tgtccaacga
    19321 ggcccgatta cgtttgatct gggcatctat ggtgccaata cgcgcctgtt taaccgccaa
    19381 ctccgtcgcc gcagtatcca gatcctgttg cgataccgcc tgagtcttag ctaactgctg
    19441 ctggcgcgcc agcgtaaccc gcgccagctt taactcagcg gctgcctgct gacgctccgc
    19501 gttcagctcc atcagggtgg cctcgacctc ttttatctgg ttctccgcct gatctgggtc
    19561 aatcacgccg agtagctgat cttttttaac gttatcgcca atggagacca gcagcgtttt
    19621 caactggccg ctcacctgcg cgccgacatc cactttacgc aacgcgtcca gttttccagt
    19681 cgccagtaca ctctgttcaa gatcgcctgg ccgcacgatt aatgtctgat aagttggcag
    19741 cggcgcattt atcattcgcc agctaaccat cccccccact aaaagaatta aaataatgac
    19801 cagataacgc tttttaaatt tctttccctt agcacgcata gaaaccctga cggcaaaatt
    19861 ttaaccagaa agtaaaccgt atctaaacaa acctgacgca ataaagatag cgccggctgt
    19921 attgacgatt ggttaatgtt tcctgtggtt caatctcgac aatcttatgt cgcggattac
    19981 gatcatgaca cagcttacag ataatacctg gtacacttca gattacatct ctcctttaca
    20041 attatttatt cgtctgacgc gcgggcaatt acagccagga aaattctggc gtaaagccag
    20101 ctttcgtcgc aagtttttaa tccgctcatt agtcatgccg cgtgcaacca gccaattact
    20161 gaccaatctc acccaatggc cgaagttaaa tacgttactt gctcgtcagc cgcgtttgcc
    20221 tattcggcta catcgtcctt atatggctgt aaatattaaa cgcgatttcg ccttagacgc
    20281 tctgtgtttt cattatcaac agatgcgcca acttttatcg cgggaacaac aagttagcta
    20341 tttaagtcag tatggcctga atcttgctaa atttgaagct aaaaccggcg agttgtttca
    20401 acttgattta gtcagtctgg tctcactgga taaagaaggt gaaagcacta ttgttgttcg
    20461 cgacgcacag ttacgtattc tggcagagat cacatttacc ctgtgtcgct ttaaccaaca
    20521 acgcacacta tttatcggcg gattacaggg cgcggcaaac gacgtccctc acgaaattat
    20581 ccagcaggcg accaaagcct gccatggtct ttttcccaaa cgcatcgtga tggaggctct
    20641 ctgtcagttt gcgcaagtct ttcaggcaga aaagattata gccgtgagta acgatgcgca
    20701 cgtttatcgt agctggcgat acatggataa aaagacgcaa atgcatgccg actatgacgc
    20761 gttttgggaa tcgttaggcg gtgaaagaat taaagggaat tactatacgc tgccgctggc
    20821 gatcgcccga aaaagcgaag cggagatcgc cagtaaaaaa cgggccgagt atcgccgccg
    20881 ctatgcatta ctcgatagcg tcgtcgaaca ggttccggcc acattcaaac gctaatccgc
    20941 ccggccccgc gccagccaaa ccacgcgcga gaacatcttt ctgaacagcg gcggcacggc
    21001 gtcaattccg cgccgcccgg cttccatcgc gacttcaatc gccaaatccg gctttgacga
    21061 gcggtggata gctttagtga taattttccg ggtattcatc ggcacattaa gcggaagttg
    21121 cgcaacccgg tgaaaaacat cggcaaagcc ctgacgatac ataaaatgtt ccatatccag
    21181 cgtaggcagc gccgtgagat gttcgcgttc ttcttcccga tcgttattaa gcaggctgcg
    21241 gaccgtcgcg gcatattttt tccccgcttc gtcgccatcc accaggacat gccactcgat
    21301 tcccatacgg cgggcgaact tcaccagcgg tttcaggcca gactgagcaa attcaatgac
    21361 tttaattccc tccgcatcaa aatgatgtcc acactgacgc gccagctcat taataaccca
    21421 ggtttccgtc tcgccttcca ccagtagcca gcaacgcgca aacagcgacg acgcgcgatt
    21481 aaagcggata tgaaaggcga tgcgccgtcc atcttccgcg cttaacccgc ccgtgcccag
    21541 acgccaggcg gcgacgcggg aagattcgcg caccagccgt acgacatgct ccaccggcgt
    21601 tagcgagagc agttcgcctg agttggttgt cgctatccgc tgtagcggta acagattgag
    21661 caattgccag gcgactgaaa gcataatggg atgtaaacgg gtttccggat cttccaccag
    21721 cagtaatggt cgcgcgtctt tatgtaaccg cagcgtccct ttcgcctgta acagcgtgga
    21781 gaaaagcccc agcaggatca cccgatgcga ccggctgccc ggtttgtcga tcatccgatt
    21841 aataatatcc agatagcgcc agctacgctg ctcattttgc gaacgccggc gcatgagtcg
    21901 gtgacgcgcc tgtcctgcgc cctgctctga gaaatagtgt tcaagcagtt gcaccatcgc
    21961 ggacagtccc tgacgaatct gcccgtcggt taaattttgc ggccgggtcg ccagctcacg
    22021 cgccagaaaa tccagttgcc gggccgtgac ttcaacatcc ggcacattgg gcaccgtgcc
    22081 gttgcgaata cgtcgcataa agcgcgcatc gcgcaaacgt agcactggca tcagacgaac
    22141 caggtggcgc acctgatcgt taatattttc caccggcaat ggctgcccat cgctattgag
    22201 aaaactgcgc agcgtcatca cgctgccatc ggcgccacat tcgccctcta gacgataaaa
    22261 aatacggtga aaatcatcct cgcaaggcga ccagcatgct tccagcgccc gataacgacg
    22321 tacccgatgc cgccctggct gcgtttcgcg aaaagtcaga ataatatgca ggtgatgctc
    22381 gcgtcctttt atgtcgccag gcggaaacca gaaatcctca cggacaaaat ggtagagatc
    22441 gagttccggc gacaataaca gagtcagcgc atccagcagg ctggatttgc cccaggcgtt
    22501 ttccccaatc agcacgttgt tttgctccag catcaacgat agtcggttga taccgcgaaa
    22561 tcctactatt tcaacgcgtt cgagaatcat gcttcctcca gaaaaacgtc accactccat
    22621 taaactcacc gcagtataac ggcaaatgct tccgcctggc gtgatattcc cccctttgcc
    22681 tggggcaact gtctgataaa tgtacggctg acggtgtcgc tttactgata gtctggaatt
    22741 cggtagtgtc atgtacgcta ttcaaacaat aaaaaagggc ccggctgttc atgttttcag
    22801 gacttttaat cattctggtt ccactgattg tgggctatct cattccactg cgacataaag
    22861 ccgcattaca actcattaac cggctactga gctggatcgt gtaccttatt ctctttttta
    22921 tgggaataag cctggcgttt ttggataacc tcgccagtaa tctggtggcg atttttcatt
    22981 attccgccgt cagtattacg attattttat tgtgtaatat cgccgcctta ttgtggctgg
    23041 aacgtatcct cccgtggcgt caccatcatc agcaggaaaa actgccttcg cgtattgcca
    23101 tggcgctgga gtcgctgcaa ctgtgcggcg tagtggtatt ggggtttatc atcggcctga
    23161 gcggactctc tgttttacag cacgccaccg aagccagtga atatacgctg atctttttat
    23221 tgttcctggt ggggattcag ctacgaaata gcggcatgac cttaaagcaa attgtgctta
    23281 accgccgggg aatgatggtc gcggtcgttg tcgtggcaag ctcattactg ggcggcgtga
    23341 ttaatgcgtt tatcctggac ttaccgctaa aaaccgccat ggcgatggcg tcaggtttcg
    23401 gctggtactc tctttccggt attttgctga cggagtcgtt tggaccggtt atcggcagcg
    23461 cggcattttt taacgatctg gcccgcgaac ttttggccat tatgcttatt cccggtctgg
    23521 ttcgccgcag ccgttcaacg gcgttgggcc tgtgcggagc gacctcaatg gactttacgt
    23581 tgccggtatt acagcgctcc ggtggcgtag agattgttcc ggcggctatc gtacatggct
    23641 ttatcctcag cctgctggta cctctcttaa tggcgttctt ctcggcctga tacctctctg
    23701 gcggtaggta tctgccgcca aaattgcgct aaatcaatct ccttgcacat tatggcagaa
    23761 atccctttta tccctttgtt cacaggcata atcttaaaca tgtatattaa atataacttt
    23821 aaaaggtgtg accatgtttt gtgtgcaatg tgaacaaacc atccgtacac cagccggaaa
    23881 cggctgctcc tacgcgcagg gaatgtgcgg taaaacggct gaaacgtccg atctgcagga
    23941 tctgctgatt gcggctttgc aaggtttgtc tgcctgggcg gtgaaggccc gtgaatatgg
    24001 catcattaat cacgacgttg ataactttgc gccgcgcgcg tttttctcca cgctgaccaa
    24061 cgttaacttc gactctccgc gtatcgtcgg ctacgcccgt gacgctatag ccatgcgtga
    24121 agcgttgaaa gcccagtgcc tgagcgtgga tgctaatgcg cattgcgaca atccgatggc
    24181 cgatctgcaa ctggttagcg acgatctggg cgaactgcaa cgtcaggcag cggaatttac
    24241 cccgaataaa gataaagccg ccattggcga gaacatcctc ggcctgcgtc tgctgtgcct
    24301 gtacggtctg aaaggcgcgg cggcgtacat ggaacacgcg cacgttctcg gtcaatacga
    24361 caacgacatt tatgcgcagt accacaaaat catggcctgg ctcggcacct ggcctgctga
    24421 tatgaacgcg ctgctggagt gcgcaatgga aatcggccag atgaacttta aagtgatgag
    24481 cattctggat gccggtgaaa ccaccaaata cggtcaccca acgccgactc aggtcaacgt
    24541 caaagcgact gaaggcaagt gcattctgat ctccggtcac gatctgaaag atctctacaa
    24601 cctgctggag cagaccgaag gcaccggcgt taacgtctac actcacggcg aaatgctacc
    24661 cgcacacggc tacccggaac tgcgtaaatt caagcatctg gtcggtaact acggcagcgg
    24721 ctggcagaat cagcaggtcg aattcgcccg cttccctggc ccaatcgtga tgacctctaa
    24781 ctgcattatc gacccgaccg tgggcagcta tgacgaccgt atctggaccc gtagcatcgt
    24841 cggctggccg ggcgttagcc atcttgaagg tgatgacttc gggccggtca ttgcccaggc
    24901 gcagcagatg gcgggcttcc cgtatagcga aattccgcat ctcatcaccg tcggttttgg
    24961 tcgtcagacc ctgctcggcg ctgccgatac gctcatcgat ctggtcagtc gtgaaaaact
    25021 gcgtcacatc ttcctggtcg gcggctgtga cggcgcgcgc ggcgagcgta actactttac
    25081 cgatttcgtc accagcgtgc cggatgactg cctgattctg actctggcgt gcggtaaata
    25141 ccgtttcaac aaactggagt tcggcgacat cgaagggctg ccgcgtctgg tcgatgccgg
    25201 tcagtgtaac gatgcttact ccgcgattat cctggcggtg acgctggcgg aaaaactggg
    25261 ctgcggcgtc aacgatctgc cgctatcgct ggtgctctcc tggtttgagc agaaagcgat
    25321 cgttattctg ctgacgctgc tgtcattagg cgtgaaaaat attgtcaccg ggccgaccgc
    25381 accaggcttc ttcacgccgg atttgctggc tatcctcaac gagaagttcg gtctgcgctc
    25441 cgtgaccact gttgaagaag acatgaagca attgctgagc gcgtaaggag gccaatgatg
    25501 acgatgccaa cctcacaatg tccctggcga atgcaggtgc atcacatccg tcaggagacg
    25561 ccggatgtat ggacaattgc gctattatgc catgactact acccttaccg cgccgggcag
    25621 tatgcgctgg tgagcgtgcg caattcagcg gaaacgctgc gcgcctacac cctttcgtct
    25681 acgccgggcg tcagtgaata tatcacgctg accgttcgtc ggattgaaga tggcacgggt
    25741 tcacagtggt tgacccatga catcaagcgc ggcgattaca tctggctgtc tgatgcaatg
    25801 ggcgatttta cctgtgacga taaaacagaa gataagtttc tgctgctcgc cgccggttgt
    25861 ggcgtaacgc caatcatgtc gatgcgtcgc tggctggcga aataccgccc gcaggccgac
    25921 gtgcaggtca tctttaacgt ccgttcgccg gatgatgtga tttttgccga cgagtggcga
    25981 cagtatccgg tcacgctagt ggcggaaaat catgccacgg aaggttttat cgcgggccgt
    26041 ctgaccacgg aattgttaca gcgcgtaccg gatttggcat cgcgcactat catgacctgc
    26101 ggcccggcgc cctatatgga tttcgttgaa cagggagtga aagcgcttgg cgtaacgcac
    26161 ttctttaaag agaagttctt cacgccggtg gcggaaacgg caaccagcgg cctgaaattc
    26221 accaaactac agccagcgca ggaattttat gccccaatcg gtacgacgct gctggaggcg
    26281 ctggagagta ataaagtacc ggttgccgct gcctgtcggg caggtgtttg cggctgctgt
    26341 aaaaccaaag tcgtttccgg cgactatacg gtgagcagca ccatgacgct gagcgaggcg
    26401 gagattgccg aaggttacgt actggcctgc tcctgccatc cgcagggcga tcttgttctc
    26461 gcataatcgg taaacgttcc atcgtaggcc cggtaagcgt cagcgccacc gggcgattta
    26521 ccactcgctt catcctttcg cccctctctc cgccaaagaa aaacgtcatc gtcatcttca
    26581 actaaacttg taaccgttat cacatttaag gagatggaga accatgaaac aaaccgttgc
    26641 tgcttttatc gccaaaacgc tggaacaggc tggcgtaaaa caaatctggg gcgtcactgg
    26701 cgactccctg aacggcctga gcgatagtct taatcgtatg ggaaccattg aatggatgcc
    26761 aacccgccac gaagaggtcg ccgctttcgc cgccggcgca caagcgcagc ttaccggcga
    26821 gctggcagtg tgcgccggtt catgtggacc gggcaacctg cacctgatca atggcctgtt
    26881 tgattgccac cgtaaccacg tccctgttct ggcgatcgcc gcccatattc cgtccagtga
    26941 aatcggcagc ggttatttcc aggagaccca cccgcaggag ttgttccgtg aatgcagcca
    27001 ctattgcgag ttggtttcca gcccggagca gatcccgcag gtactcgcca tcgccatgcg
    27061 caaagcggtg ctaaatcgcg gcgtctccgt ggtcgtactt ccgggtgacg tggcgctgaa
    27121 acccgcgcct gaaaacgccg tcacccattg gtaccatgcc ccgcaccccg tcgttacgcc
    27181 ggcggaggaa gagctgaaaa aactggcgca actgctgcgc tactccagca atatcgcatt
    27241 gatgtgcggt agcggctgcg cgggcgcgca tgaggagttg gtcgcgttgg cggcaaaact
    27301 aaaagcgcca atcgttcatg ccctgcgcgg caaagagcac gttgagtacg ataaccctta
    27361 tgatgtggga atgaccggcc tgattggctt ctcttctggc ttccacacca tgatgaacgc
    27421 cgatacgctg atcctgctcg gcacccagtt cccctatcgc gccttttatc cgagcgatgc
    27481 caaaatcatt cagattgaca tcaacccggg cagtattggc gcgcacagca aagtcgacat
    27541 ggcgctggtg ggcgatatta aagccacgct tcgcgccctg ctgccgctgg tggaagaaaa
    27601 aagcaatcgt aaattcctcg ataaagctct ggaacactat cgggacgccc gtaaagggct
    27661 tgatgactta gccaaactca gcgataaagc catccaccca caatatctgg cgcaacaaat
    27721 tagtcatttc gccgctgacg acgctatttt tacctgcgat gtcggcacgc cgaccgtctg
    27781 ggcggcccgc tatctaaaaa tgaacggcaa gcgccgcctg ctgggctcgt ttaaccacgg
    27841 gtcaatggcc aacgccatgc cgcaggcgct cggcgctcag gccaccgcgc cgggtcgtca
    27901 ggttatcgcg atgtgcggtg atggcggctt cagtatgctg atgggcgatt ttctctcggt
    27961 ggtacagatg aagctgccga taaaaatcgt cgtctttaat aacagcgtgc tgggctttgt
    28021 ggcgatggaa atgaaagctg gcggttacct taccgacggt accgaactgc acgacaccaa
    28081 tttcgcgcgt atcgccgaag cctgcggcat taccggtatt cgcgtggaaa aagccgcaga
    28141 cgtggacgga gcgctacagc gcgcgttttc catcgatggc ccggtactgg ttgacgtggt
    28201 cgtggcaaaa gaagagctgg cgatcccgcc gcagatcaaa ctggaacaag cgaaaggctt
    28261 tagcctgtac atgctgcgcg ccattattag cggccgcggc gatgaagtga tcgaactggc
    28321 gaaaacaaac tggctaaggt aaaacagtgc acatcacctt ttaaaatcca gggatgtgcc
    28381 atgattgatt tacgcagtga taccgttacc cgaccgggcc gcgccatgct cgaggcgatg
    28441 atgaccgccc cggtcgggga cgacgtatac ggcgatgccc ctaccgttaa cgcccttcag
    28501 cgctacgccg ccgacctttc cggtaaagaa gcggcgcttt ttttacccac cggcacccag
    28561 gccaatctgg tcgcgctgct tagccattgt gaacgcggcg aagagtatat cgtcggtcag
    28621 ggcgcacata attatctcta tgaagctggc ggcgctgcgg tgctcggcag cattcagccg
    28681 cagcctattg atgccgccgc ggacggtacg ctgccgctgg agaacgtagc ggcgaagatt
    28741 aaagcggatg acatccactt cgcgcgcacg cgcttgctca gtctggaaaa tacgcataac
    28801 gggaaagtgc tgccgcgcgc gtatctgaaa gacgcctgga cgtttacccg cgaacgtggg
    28861 ctggcgctgc acgttgacgg cgcccgaatt tttaacgcgg tggttgccta cggctgtgag
    28921 ttaaaagaga ttacgcagta ttgcgactct tttaccatct gcctgtcaaa aggtctcggg
    28981 acgccggtcg gttcgctgct ggtcggcaac cgcgattaca ttaaacgcgc gacgcgctgg
    29041 cgtaaaatgg tcggcggcgg aatgcgtcag gccgggattc tggcagcggc cggactgtat
    29101 gcgctgaagc ataacgtggc gcgtctgcaa gaggatcatg acaacgccgc ctggctggcg
    29161 cagcagcttc gcgaagcggg cgcggatgtc atgcgccacg aaacgaatat gctgtttgtt
    29221 cgcgttggcg aagcacaggc cgccgcgctt ggcggctatt tgcgggaacg gaatatcctg
    29281 attaacgccg cgccgattgt gcgtctggtg acgcatctgg atgtctctcg cgaacagctt
    29341 gccgacgtcg tcgcccactg gcgcgccttt ttagcccgct aaggagagca acgtggcgca
    29401 acgcattctg gtcctcggcg ccagcggcta tatcggtcag cacctggtct ttgcgctaag
    29461 tcagcaagga catcaggtgc gggcggcggc gcggcgcgtg gaacgtctgg aaaaacatcg
    29521 cctcgccaac gtcagttgtc ataaggtcga tctgcactgg ccggaaaatt tacccgcgct
    29581 gcttcgcgac attgataccg tttactatct ggtacacggc atgggcgaag gcggcgactt
    29641 tatcgcccat gagcgtcagg cggcgctcaa cgtgcgcgac gcgctgcgcc agacgccggt
    29701 taaacaactt attttcctca gttcattgca ggcgccggcg catgagcaat ccgatcacct
    29761 gcgcgcccgc cagcttacgg ctgacacgct gcgcgacgca ggcgtaccgg tgacggaatt
    29821 acgcgccggg atcatcgtcg gcgcaggctc cgccgccttt gaggtcatgc gcgacatggt
    29881 ttacaacctg ccaatactca cgccgccgcg ctgggtgcgt tcgcgcacca cgcccatcgc
    29941 cctggaaaat ttactctact acctggtcgg cttactggag caccctgcgc acgagcatcg
    30001 tattctggaa gccgccgggc cgcaggtatt aagttatcag cagcagtttg aacgttttat
    30061 ggccgtcagc ggtaaacggc gtccgctgat cccggtgcct tttccgaccc gctggatttc
    30121 ggtctggttt ttaaacgtca ttacctccgt gccgccaact accgcaaaag cgttaatcca
    30181 gggattaagg cacgatttgc tggccgatga cgccgcgtta aaaaagttga tcccccaaac
    30241 gcttatcacc tttgatgacg ccgttcgccg cacgctgaaa gaagaagaaa aactggtgaa
    30301 ctccagcgac tggggctacg acgcgctggc cttcgcccgc tggcgtcccg aatacggcta
    30361 ttttccaaag caggcgggct ttaccgcgca gaccccggcc agcctatcgg cgctatggca
    30421 ggtcgtaaat cggctgggtg gcaaagaggg ctattttttc ggcaatattt tgtggcagac
    30481 gcgcgccgcg atggaccgtc tggtggggca taaactggcg aaaggccgcc cgtcgcatac
    30541 cttgctcaag cctggcgata cggtagatag ctggaaagtg atcattgtcg aaccagaaaa
    30601 acagctcacg ctcttgtttg gcatgaaagc gccgggtctg gggcggctta gcttcacgct
    30661 gcacgataaa ggccgctacc gcgaaattga cgtgcgcgcc tggtggcatc cacacggaat
    30721 gccgggcctg atttactggc tactgatgat cccggcgcac ctgtttattt tccggggaat
    30781 ggcaaggcgt attgcccgac ttgcagaaca aatcacagaa aaatgagaaa aagttgctgt
    30841 attctttcgt gtttcccatt gcataccgac gtaattcacg gaagaatgcg cacgacggtt
    30901 tattaaacac agtggattga tatgaaggta ctggttaccg gcgccaccag cggcttaggt
    30961 cgaaacgcgg ttgaattttt gcgcaataaa ggcatcagcg tcagagcgac gggtcgcaat
    31021 gaagcgatgg gcaagctgct tgaaaaaatg ggcgcggaat tcgtccatgc ggatttaacc
    31081 gaactggtct cctcgcaggc taaagtgatg cttgccggga tcgacacgtt gtggcactgc
    31141 tccagcttta cctcgccctg gggaacccaa caggctttcg atctggcgaa tgttcgcgcc
    31201 acccgccgtc tgggagaatg ggcggtcgcc tggggcgtgc gcaattttat tcatatctcc
    31261 tctccctcgc tctattttga ttaccaccat caccgtgata tcaaagaaga tttccgcccg
    31321 catcggtttg ccaatgagtt cgcccgcagt aaagccgccg gcgaagaggt gattaatctg
    31381 ttggcgcagg ccaatccgca aacacgtttt acggtattgc gtccacaaag cctgtttggc
    31441 ccgcacgata aagtatttat cccacgtctg gcgcatatga tgcaccatta cggtagcgtc
    31501 ttattaccgc acgggggcag cgcgctggtc gatatgacct actatgaaaa tgcgatccac
    31561 gccatgtggc tggccagcca gccgggctgc gatcatctgc cttctggccg cgcttataac
    31621 atcactaacg gcgaaaaccg caccttacgc agcatcgtac aaaagttaat tgatgaattg
    31681 actatcgact gccgcattcg ctctgtgcct tacccgatgc tggatatgat cgcccgcagt
    31741 atggagcgct tcggcaaaaa atccgccaaa gagcccccgc taacgcatta cggcgtgtca
    31801 aaactgaatt ttgattttac gctcgatacg actcgcgcgc aggacgagct gggctaccag
    31861 cccatcgtca cgctggacga aggcattgag cgcaccgccg cctggctgcg cgatcacgga
    31921 aatttaccgc gttaatcctg gccgtacttc tccagtaatg cttcggcaat cgcctgcgtt
    31981 tcggcatctg cgataccgtt ccattgcgcc ggacggaagt gcatctggaa cgccataatc
    32041 acccgctgtt gctcgcgcgc cgtcatatcg gctttgactt catagccata gcgcgagagt
    32101 aacgcaagca ccgttgcggt atcgactggc gtatacggcg cgcgtccagc cagataaaac
    32161 gccacacgct gggcgtcagg ccaggcgcca atcccctgtg ccgccagctc gcgccacggg
    32221 aagcgcgggc cgggatcgtc tttacgctgc ggcgcgatat ccgcatgggc caccacattc
    32281 tgcggtttga tgtcatagcg cgcgataatg tccttcgcta acgggatcaa tgcctgaatt
    32341 tgcgcggatt caaacggcgc gaaagatttc accccgccgg acattcgcca gccgcgattt
    32401 tccagctcaa tgccaataga cgtatcattg agacgcgtgg cgcctcgcca gaaactgacg
    32461 cccgcatgcc aagcctgatc ctgttccggc accagttgcc agatgcgcgg tttaccgcca
    32521 tataatggcg gggttgcggg aatcaggtaa tgcgaactga cgttgcgacc cgttaacgtc
    32581 gccagcgaaa cgtcaaagtt ttccgccgta tagtgaatca ccaggacttt aatgcgcgga
    32641 taggccgcct gcgcccgatg tcgggtatca agctgatatc cctctttatc gataattcct
    32701 ttttcgctcg cgcagcctgt taacagcaac gcgagaccaa ccagccacag tagcgctttc
    32761 atcggcgcgt tttcaccgcc gttccgctga cgctgaccat cagcatactg ccatccttgc
    32821 cgacagtttc gtaatcaata tcgatgccta ccaccgcatc ggcgcccaac gctttagcct
    32881 gctcgccaag ttcctgaaaa gcgatttcac gcgctttacg cagctctttc tcatacgcgc
    32941 cggaacgtcc gccgacgata tcccgaatgc cggcgaaaaa atcgcggaaa atattggcgc
    33001 ctaaaatggc ttcgcccgtt accacaccgc aatactccac gatgctttgt ccttccagcg
    33061 ttggggttgt tgaaaactgc atagtgaatc tcccgggtta gctaagcaca cgatctcaaa
    33121 cgcattatca agctgatacg ctatcattga aaggatataa ttgattatcg tagatcggtt
    33181 tttgctcgat cgcctataag gaaatcatca tgcgctattc taaactctct ttgctcatcc
    33241 cgtgcgcgct tctgcttagc gcctgtacga ccgtcactcc cgcctacaaa gataatggcc
    33301 cgcgtatcgg cgcgtgtgtg gaaggcggcc cggacagcgt ggctcaacaa ttttacgact
    33361 accgtattca acaccacagc aatgatatcg ccgcgcttcg cccctacttg agtgataacc
    33421 tggcgaaatt gttgaccgac gccagccgcg atacggaaca ccgccagttg atgagcggcg
    33481 atatgttctc cagccgcgct acgctgccgg atagcgccaa cgtcgccagc gcatcaacca
    33541 ttccgaaccg agatgcgcgc aatattcctc tgcgggtggc gttaaaacag ggcgatcaaa
    33601 gctggcagga tgaagtgctt atgattcacg aaggctcatg ctgggtgatt gacgacgttc
    33661 gctatctggg cggagatgtc catgcccctg ccggtacgct gcgccagtcg atagaaaacc
    33721 gttaacagtc agtattcccc gcttttgcac ccataacccc gtaaattgtc tggcattctg
    33781 cacgggatgc cgacaattct tcttacctac tattcctcct gctattttgt gctatgttta
    33841 gggaagaatg tgggatatat ttaactttta acgcataaat attgcataac tattctgcga
    33901 aaggtactat ctgcggcttc aatagctatc agactgcctg tatacgagtg tcaatgagta
    33961 ttcaattaaa cggcattaat tgcttttacg gcgcgcatca ggcgctgttc gatatcacgc
    34021 tggattgccc cgaaggcgaa acgctggtgt tgcttggccc aagcggggcg ggtaaaagtt
    34081 cgctgctgcg tgtactcaat ctgcttgaga tgccgcgctc cggcactctg actatcgccg
    34141 ggaaccattt tgactttacg aaaacgccgt ccgataaggc gattcgtgag ctacgtcaaa
    34201 atgtcggaat ggtctttcaa caatataatc tttggccgca tctcaccgtt gtgcagaatc
    34261 tgattgaagc gccctgccgc gtactgggtc tgacaaaaga tcaggcgctg gcgcgcgcag
    34321 aaaagctgct ggagcgttta cgtctgaagc cctatagcga tcgttatccg ttgcaccttt
    34381 ccggcggtca gcagcagcgc gtcgcgattg cccgcgcgct gatgatggag ccgcaggtgc
    34441 tgctgtttga tgaaccgacc gccgcgctgg acccggaaat taccgctcaa atcgtcagca
    34501 ttattcatga gctggcggaa acgaacatta ctcaggtgat cgttacgcat gaagtcgaag
    34561 tggcgcgtaa gaccgccagt cgtgtgattt atatggaaaa tggtcacatc gtcgagcacg
    34621 gtgatgcggg ttgctttgct caccctcaga ccgaagcgtt caaaaactat ctctctcact
    34681 aagattcggg acaatgacaa tgaaaaaagt tctgattgcc gcgctaattg caggctttag
    34741 cctttccgct acagcagccc agaccattcg ttttgcgacc gaagcgtcct atccgccgtt
    34801 cgaatcgatg gatgctaata acaagattgt cggctttgac gtcgacctgg ccaacgcgct
    34861 atgtaaagag atcgacgcct cctgtacctt taccaatcag gcgttcgaca gcctgatccc
    34921 cagcctgaaa ttccgccgct tcgacgctgt aatggcggga atggatatca cgccggaacg
    34981 tgaaaagcag gtgctgttta ccacgccata ttacgacaac tccgcgctgt tcgtgggtca
    35041 gcagggcaaa tacaccagcg tcgatcaact gaaaggtaag aaagtcggcg tacagaacgg
    35101 tacgacgcac cagaaattca tcatggataa gcatccggaa atcaccaccg taccgtatga
    35161 cagctatcag aacgcgaagc tggatctaca aaatggccgt atcgacgctg ttttcggcga
    35221 cacggcggtc gtgaccgaat ggctgaaagc caatcctaag ctggcgccgg tcggcgataa
    35281 agtcaccgat aaagattatt tcggcaccgg cctgggtatc gcggtacgtc agggcaacac
    35341 cgagctgcag cagaaattca atactgcgct ggaaaaagtg aagaaagatg ggacttacga
    35401 gaccatctat aacaaatggt tccagaagta atctttgatg aacgaatttt ttcctttagc
    35461 aagcgccgcc gggatgaccg tcggccttgc cgtctgtgcg ctgatcattg gcctcgcgtt
    35521 agccatgttc tttgccgtct gggagtccgt aaaatggcgc ccgattgcct ggataggctc
    35581 cgcgctggtc actattttgc gcggcctgcc ggaaattctg gtggtgctgt ttatctattt
    35641 cggctcctcg caactcctgc ttacgctgtc tgacgggttt accctccatc tcggttttac
    35701 gcagatcccg gtgcaaatgg agattgagaa ctttgacgtc agtccgttcc tgtgcggcgt
    35761 gattgcgttg tccctgctgt atgcggccta tgcgtcgcag acgctacgcg gcgcgctgaa
    35821 agccgttccg tctggtcagt gggagtcggg tcaggcactg ggattatcaa agacggcgat
    35881 ttttttccgt ctggtgatgc cgcagatgtg gcgtcacgcc ctgccagggc tgggtaatca
    35941 gtggctggtg ttgctaaaag atacggctct ggtcagcctt atcagcgtta acgatctgat
    36001 gttgcagacc aaaagtattg ccacacgcac ccaggaaccg tttaactggt acattattgc
    36061 ggcggctatt tacctggtca ttacgctgat cagtcagtac attctcaaac gcatagacct
    36121 gcgcgcaaca cgttttgagc ggaggccgga ctaatgcttg agtacttacc tgaactgcta
    36181 aaagggctat acaccagcct gacgctgacc gtggcttcta ttgccgtcgc tttggtgctg
    36241 gcgttagttt ttaccatcat cctgacgcta aaaacgccgt tcgtggtgtg gctggtgcgc
    36301 ggctatatca cgttgtttac cggtacgccg ttgttggtgc aaattttcct gatctactac
    36361 ggacccggtc aattcccgac actgcaagag tatccgctac tctggcatct actgtctgaa
    36421 ccgtggctgt gcgcactgat cgcgttgtcg ctaaacagcg ccgcttacac cacgcagcta
    36481 ttttatggcg cgattcgcgc gattccggaa ggtcagtggc agtcctgcgg cgcgctgggg
    36541 atgagtaaga aagatacgct ggcgattttg ttgccctatg cgtttaaacg cgccctctcc
    36601 tcctattcta atgaggtggt actggtcttc aaaagtacct cgctggccta taccatcacc
    36661 ttgatggagg tcatggggta cagtcagttg ctctatggtc gtacctacga tgtggtggta
    36721 tttggcgcgg caggcgtaat ttacctggtc gtcaacggtc tattgacgct gatgatgcgt
    36781 ttgattgagc gtaaagccct ggcgtttgag cggcgcaatt aaccaggcag gataaggcat
    36841 tctcgccgcc gttcgacaat ggtcagatgg cgctgcgctt atcaagccta cgatgcataa
    36901 tattgaataa acccgacgga caagtggtta acttgtccgt ctttttttat ccattttaaa
    36961 atatttaatc atttttattg catacaaatt caattgatgg cattgtaaat ctatgccgca
    37021 gacacggcgc ataatcataa gattacggga gtgacatcat gaaaaagtta gttctggctg
    37081 cattactcgc ctctttcgcc actggcagca tcgccgctga aaaaatcaat ttcggggttt
    37141 ccgccaccta tcccccgttt gaatccctgg atgcgagtaa taaaattgtg ggcttcgata
    37201 tcgatctggc aaccgcatta tgcaagcaaa tgcaggcaga atgtactttt accaatcatg
    37261 ctttcgatag tcttatcccg gcgctgaaat tcagaaaata tgatgccgtc atttccggaa
    37321 tggacattac cccggagcgc agtaagcagg tcgcctttag caatccctat tatgcgaact
    37381 ccgcgctggt gattgccaaa aaagacacct ataaaacctt taccgatcta aaaggtaagc
    37441 gtatcggtat ggaaaatggc accacgcatc aaaaatatct ccaggataaa catccggagg
    37501 tcaaaaccgt ggcctacgac agctaccaga atgcgattat cgacctgaaa aatggccgta
    37561 ttgacggcgt ctttggcgat accgcagtgg tcaatgagtg gctgaaaacg aatccgcaac
    37621 tgggtccggc aacagagaaa gtgaccgatc cgcaatactt cggtaccgga cttggcatcg
    37681 cggtgcgccc ggacaataag gcgttgctgg aaaaactgaa taatgcgctg gccgccatta
    37741 aagcggacgg cacttatcag aaaatcagcg atcagtggtt cccgcagtaa aacgtatgtg
    37801 attagcccac cgtgttgcga aatggcagta taaatacctt attcagccca cgggccgcta
    37861 tcggaaacta tcctggcctg ataagcgcag cgccattgag cattctacag tttgtcatca
    37921 gtctcaaagg cctgcatcaa caggcgattc ggactcatac ttgccgggtg acgctaacgc
    37981 gtacccggct tacaacattg ttatgttttt agacaacatc cagacccaga cggcgatact
    38041 gctccgccgg agcgtcattt tctttcatca aacggataag taagttgatc atccttgctt
    38101 cgatggcctc atcatgaata ggatgttgct gctgcggatc gtctctgaga tcaaacaaga
    38161 gatgaccaaa gctattcaca cctttatatt tttccctggc cggaatacgt aatacctgaa
    38221 gccctttagt gaatttaaac ggaggtgcca gagataattt tcccagttca tccacgtcat
    38281 aacgcgcatt catcttgatc ggcattaacg tgtagttcgc aatgtcatgc tcacgccccg
    38341 gctgcgcggc ccgcatataa acatagcgtc cgtcggtaac attaacatgt ccgctaaaca
    38401 cgccaaacag cgcgccttcc ctgacgggtt catcactggc aatgactttc gccagaggtt
    38461 ggccctgcat atctgcggga ataggttgct gaaaataatc cagtagcgtt ggcgcccagt
    38521 caatcatctg caccagcgac tgccgtcgcg ctccgcatac cgcgctgcgc gggtcccaga
    38581 taaacagcgg gttattcgcc acctcgttat aatagggcat ttgattttta gcccaccaac
    38641 cgtgctcccc cagcaagaag ccgtgatcgg taccgacaat cagcatcgta tcgcgccaga
    38701 gatcgtgttc atccatcaga tcaaggatac gtcccagatt gcggtcgcac atggaaacca
    38761 gggcccgata acgacagcga atatgcgcta tcgcctcctc actttcactg actttgccgc
    38821 gcggccagtc ataatgcgag ccttgccact catcgtcata gagcgataaa tattcctcgg
    38881 tggtataaaa cggctcatgc ggatcgaacg tctcaacctg caataaccag ttatcttcgg
    38941 catgattttt atggataaaa tcgcacccgg cgtcaaaaac tttcgtctgg ggaaaatcgg
    39001 cttcctgctg gatgtattcg cggttcgccc agtcatgacg ccatagcccg gaaacgccgc
    39061 ctccggtttg tttttgtgga acgcgcagta cttccggaat gggcggctcg ccaacacttg
    39121 ccttccagtg atcgccctcc tgaccgcgta ctacgtccca ggagctatag cggttatggt
    39181 agttaccgcc gccgtcttcc cagtaatgca gatgatcgct gataagatgg gtgtagatcc
    39241 ccgctttttt caataattcc ggcatggaat catcaaaggg ttccagcggc ccccactcac
    39301 gatgcaggaa attatagcgc ccggtgtgca gttcccgacg ggctggcata cagggcatac
    39361 tgccgacata actattgtca aaggtggcgg catgtgccgc caggcgttga aagttaggcg
    39421 ctttcgttag caaatcacca tagggcggca aatagttttt attcagactg tcaaacagca
    39481 gaataatcgc tttcatgact caccctcatt tgttgagcag gtgcggaaaa tttttctcta
    39541 ccacatcgta aatctgttta cctattgatt cgctatccat gatattttca atgggaatga
    39601 gatattgtcc gtgtttagga tcgaggctaa caacatcaag caattttttc gaaatcgcat
    39661 aaatatctgc ccagtcggta aatccaccga cctctcccgc tgccgtatgc tccatatcaa
    39721 aagagaagtc atattttgct aacgcttttt taacaacagt ctgtaacatt acgctactgc
    39781 ctacaccata accgcatacg aataaaatat ttacagaatc tttcataata aaatccttta
    39841 tatataaacc gaatcaatta aatggaataa ggaccaagat ggaacgttga agcaataaat
    39901 ttcagtaatt cacaaatcgc aggccacaga gtcgcccagt caaatattcc cgtccagccc
    39961 acgccttctt ttgccagccc ggttaaagga atggcccata ccgtaccgaa agtctgaata
    40021 atccctaaca ggaaagtaca aataataacg gaacgatatc cccccattcg gttggctaat
    40081 acgccgatgg gaccgccgga aaagaagagc ggaacaaaac caggcaatac cataataggg
    40141 ctatggatga gcagcaggat gcccatggaa aaaatcgtgc cgaaagtaca aaagacgaat
    40201 cccagcgtgg ccgcgttagg cgaaaaaggt aataaagcag caacatccac agccggtatg
    40261 gcgttaggaa taaagcgatc ctgccatcct ttaaacgaac cgttaatttc accaaccatc
    40321 atccgcacgc cctgcagcaa gatgaccata tacatagaga attgcaggcc cagattgata
    40381 atatagatat accagggttt gcctttcgcc attaactgta cgttatcgat ccctgtcgcc
    40441 aatagaaaac cgccaacgaa gagcgtcatc acaatggcga ttgccgtcac gttgtggtta
    40501 aaaatagcta accaaccggg aagtttcagg ttttcggcgt catgcttttc cggatcgccg
    40561 aatttatgcg cgaatttcga gaaaaaccac agccccagca tctggttatg cgcgatggta
    40621 aaaccggcgt tattggtcac tttggcgatg ggtttaacaa taagcgtggt tgaaaacgcc
    40681 caaaagaccc cggtcaatac cccggcaatc acaatggatt gtacccaacc gaaccctagc
    40741 cagaagacga ttaaccacag taccgcctgt gaatgagaga ccccggtatt accggtaaga
    40801 aatatacctt ttgcgccggt ataacggcca aataaaacta atatcaggtt agtaaaaaac
    40861 gccagtacaa aaacgtatcc tacatagccg aaattatcgc ccagcgctat ttgcgtcgca
    40921 gctttcatgg cgtatgaatc cattaagtat ccatgtacgc cataagcctt gctgactgct
    40981 tctgcaaccg gtttaaaagt ggctgaaaat tgaaagccgc caaataacac catcattaaa
    41041 ccgaccatcg cgctgatcat accggtgata atttttatag gcgtcttttt atccagcgca
    41101 tagccaacac cgactaatat cccaattaat attgccggtt cagttaaaaa cgtttgaata
    41161 acatctataa atttggcaaa catcgtctga acgccctcca taagcgtgtc tattcgttgt
    41221 cataattgac ccctttactg acgttacgta ttgcttcgct gatgctattg aaagttaccc
    41281 gataaaccac cttgt
//
LOCUS       DAJVKX010000029        40495 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000029 DAJVKX010000000
VERSION     DAJVKX010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 40495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40495
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.029"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            484..840
                     /locus_tag="OPY25_001515"
     CDS             484..840
                     /locus_tag="OPY25_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HCS0927159.1"
                     /translation="MITLYGIKNCDTIKKARRWLEEHGIDYRFHDYRVDGIDLPLLNT
                     FIAELGWQPLLNTRGTTWRKLDEGHRSGITDADSAAALMVEQPAIIKRPLLCAPGKPM
                     LLGFSESRYQQFFDEV"
     gene            844..1971
                     /gene="dapE"
                     /locus_tag="OPY25_001516"
     CDS             844..1971
                     /gene="dapE"
                     /locus_tag="OPY25_001516"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HCS0927160.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDVGCQALMIERLRKIGFTIEHMD
                     FGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARNERLDYCLV
                     GEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDRGNDFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKERVHALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            1999..2199
                     /locus_tag="OPY25_001517"
     CDS             1999..2199
                     /locus_tag="OPY25_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HCS0927161.1"
                     /translation="MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPP
                     HRDFNDKWDDEDDWPKKDQPKK"
     gene            complement(2226..4241)
                     /gene="tmcA"
                     /locus_tag="OPY25_001518"
     CDS             complement(2226..4241)
                     /gene="tmcA"
                     /locus_tag="OPY25_001518"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HCS0927162.1"
                     /translation="MSDIDALRALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAVLP
                     GDWWVAPDAPAQPRCTPQALQTLLGREFRHAIFDAWQGFDAAAFAALSGTLQAGSWLL
                     LLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWP
                     SYPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISQMAGT
                     AIVTAPAKTATDILAAFAGERFCFMAPDALLASGARADWLVVDEAAAIPAPLLLQLVS
                     RFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRWAPECPLENIVSEALI
                     FDDEAFAQAPHGGIAISAFYQQAWGKTPALPRAVYQLLSGAHYRTSPLDLRRMMDAPG
                     QHFLQATANNRVAGALWLVEEGGLSAELSQAVWCGFRRPRGNLVAQSLAAHGSDPLAA
                     TLVGRRVSRIAVHPARQREGIGQQLIACACEQAAQCDYLSVSFGYTPELWRFWQRCGF
                     VLVRMGSHREASSGCYTAMALLPLSDAGQRLAQQEHRRLRRDADILTQWNGEAIPLAA
                     LREQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAEL
                     CARLRISGRKALLALQRAQAAQALIALDAGRTQRLRDVMPGGGDHAG"
     gene            complement(4257..5120)
                     /locus_tag="OPY25_001519"
     CDS             complement(4257..5120)
                     /locus_tag="OPY25_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HCS0927163.1"
                     /translation="MRWQGRRESNNVEDRRNRPGGPSLGGPGFRLPRGKGGIILLVVV
                     VVAGYYGVDLTGLLTGQPVSQQQSTRSISPNDDEAAKFTSVILATTEDTWGQLFQKMG
                     RGYQQPKLVMYRGMTRTGCGAGQSVMGPFYCPADGTVYIDLSFYDVMKNKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNASQTEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLEAGDLEEALNAAQAIGDDRLQQQGQGRVVPDSFTHGTSEQRYSWFKRGFDSGD
                     PAQCNTFGKNF"
     gene            complement(5252..5965)
                     /gene="purC"
                     /locus_tag="OPY25_001520"
     CDS             complement(5252..5965)
                     /gene="purC"
                     /locus_tag="OPY25_001520"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCS0927164.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNHFIMTKLAEAGIPTQMERLLSDTECLVKKLEMVPVECVVRNRAAGSLV
                     KRLGVEEGMELNPPIFDLFLKNDALHDPMVNSSYCETFGWVSQENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLDKMDKDRFRQSL
                     GGLIEAYEAVAHRLGVKLD"
     gene            complement(6140..7174)
                     /gene="bamC"
                     /locus_tag="OPY25_001521"
     CDS             complement(6140..7174)
                     /gene="bamC"
                     /locus_tag="OPY25_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HCS0927165.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDESYLDA
                     APLAELHAPAGMILPITTGDYVIPVTKGSGAVGKALDIRPPAQPLALVSGARTQFSGD
                     TATLLVENGRSSTLWPQVVSVIQAKNYPIEKRDDASQTLTTDWVSWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLVNLEQAGKPVADAASLQRYSTEMMNVISAGLDKTATDAAN
                     AAQNRSAATMDVQSAADDTGLPMLVVRGPFNLVWQRLPAALEKVGMKVTDSTRSQGSM
                     AVTYKPLSDSDWRDLGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFNK"
     gene            complement(7191..8069)
                     /gene="dapA"
                     /locus_tag="OPY25_001522"
     CDS             complement(7191..8069)
                     /gene="dapA"
                     /locus_tag="OPY25_001522"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCS0927166.1"
                     /translation="MFTGSIVALVTPMDEKGNVSRSCLKKLIDYHVANGTSAIVSVGT
                     TGESATLSHDEHGDVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPTQEGLFQHFKAIAEHTDLPQILYNVPSRTGCDMLPETVGRLAEIKNIIAI
                     KEATGNLTRVHQIKELVSDDFILLSGDDASALDFMQLGGHGVISVTANVAARDMADMC
                     KLAAEGQFAEARAINQRLMPLHNKLFVEPNPIPVKWACKALGLVATDTLRLPMTPITD
                     HGRDIVKAALQHAGLL"
     gene            8215..8787
                     /locus_tag="OPY25_001523"
     CDS             8215..8787
                     /locus_tag="OPY25_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HCS0927167.1"
                     /translation="MTPSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GDEFTFIMLLSGTWNAITLIESTLPLKGAELDLLIVMKRTSDRPRPAMPATVWVQVEV
                     ADSPHLIERFTALFNSHEMNIAELVSRTQPAEDDKAAQLFIQITAHSPASQNSANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            8787..9257
                     /gene="bcp"
                     /locus_tag="OPY25_001524"
     CDS             8787..9257
                     /gene="bcp"
                     /locus_tag="OPY25_001524"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HCS0927168.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDENHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFNDFKTSNHHDVVLNWLKENA"
     gene            complement(9304..10443)
                     /locus_tag="OPY25_001525"
     CDS             complement(9304..10443)
                     /locus_tag="OPY25_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCS0927169.1"
                     /translation="MKIVIAPDSFKESLSAMAVAEAIEKGFREIYPDADYVKVPMADG
                     GEGTVQSMVEASGGRYVDQWVQGPLGQPVTARWGMLGDSDTAVIEMAAASGLHHVSPE
                     LRNPLNTTSYGTGELIVAALERGVKRIILGIGGSATNDGGAGMMQALGVILRDKQGRS
                     LSPGGEALAALASIDLSGCHPLLRKVSITVACDVNNPLCGPQGASAIFGPQKGATAEM
                     VNSLDAALENWGRHIYQATGREVINAPGAGAAGGMGAALLGLLNAELRAGVEIVVETL
                     QLEQAVKDADLVITGEGRLDSQSICGKTPIGVARVAKRHHKPVIALAGGLQHDHHVVY
                     QQGIDAALSILSHIVTLPEALHEAEYNLSLSARNVAAIWRLARQA"
     gene            complement(10449..11717)
                     /locus_tag="OPY25_001526"
     CDS             complement(10449..11717)
                     /locus_tag="OPY25_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004090684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCS0927170.1"
                     /translation="MTSISTLGAIAALVVAIVLILRKVSPAYGMMAGALVGGLIGGAD
                     LLQTVSLMVSGAQGIVNAVLRILAAGVLAGVLIESGAANTIAETIVRKVGETRALLAL
                     AIATLCLTAVGVFIDVAVITVAPIALSIARNAGLSKSAILLAMVGGGKAGNVMSPNPN
                     AIAASDAFHVPLTSIMLAGVVPGIVGLIIAYLLAKRLNNKGAGVADHEVTHHDDSVAR
                     PGFLVAISAPLVAIFLLSLRPFVGISIDPLIALPVGGLVGLLLMGRARHCNQYMVAGL
                     MRMAPVAIMLLGTGTLAGIIANSELKDVLIHGLTASGLPSWLLAPVSGAMMSMATAST
                     TAGTAVASGVFSPTLLELGVSALAGAAMIHAGATVLDHLPHGSFFHATGGSVNMQIHE
                     RLKLMPYETLVGLAITFISTLMFGFFGFAG"
     gene            complement(11785..12972)
                     /locus_tag="OPY25_001527"
                     /pseudo
     CDS             complement(11785..12972)
                     /locus_tag="OPY25_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001667973.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(13249..14316)
                     /locus_tag="OPY25_001528"
     CDS             complement(13249..14316)
                     /locus_tag="OPY25_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCS0927171.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFSILFFFSGLLAPLLV
                     AIVLAYLLEWPTARLQAIGCSRRWAASIVLILFVGILLLMAFVVMPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRTRMLNMGDSVVKYSLASLVGLL
                     TLAVYLVLVPLMVFFLVKDKEQMLNAVRRVLPRNRGLAGQVWNEMNQQITNYIRGKVL
                     EMVVVGVATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGLGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVVHAWPDGQVTDASS"
     gene            14524..15987
                     /gene="bepA"
                     /locus_tag="OPY25_001529"
     CDS             14524..15987
                     /gene="bepA"
                     /locus_tag="OPY25_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HCS0927172.1"
                     /translation="MFRQLKKNLVATLIAALALGQVAPAFADPADTLPDMGTSAGSTL
                     SIGQEMQMGDFYVRQLRGSAPLINDPLLVQYINALGMRLVSHADSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYADNESQLASVMAHEISHVTQRHLARAMEDQKRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRAGFD
                     PQAMPSFLEKLLDQARYSTRPPEILLTHPLPESRLADARNRANQMRPVVVQSSADFYF
                     AKARALGMYNSGRNQLTSDLLDQWSKGNVRQQHAAQYGRALQAMEASKYDEARKTLQP
                     LLSAEPNNAWYLDLATDIDLGQKRANDAINRLKNARDLRVNPVLQLNLANAYLQGGQP
                     KAAETILNRYTFSHKDDGNGWDLLAQAEAALNNRDQELAARAESYALAGRLDQAISLL
                     SSASAQAKLGSQQQARYDARIDQLRQLQERFKPYTKM"
     gene            16027..16386
                     /gene="arsC"
                     /locus_tag="OPY25_001530"
     CDS             16027..16386
                     /gene="arsC"
                     /locus_tag="OPY25_001530"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461430.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HCS0927173.1"
                     /translation="MTDTIKIYHNPRCSKSRDTLNLLKSNGVEPEVVLYLDTPADAAT
                     VRELLRMLGMSSARELMRQKEDLYKTLHLADSQLSEEALIQALVEHPKLMERPIVVAN
                     GQARIGRPPEQVLDILG"
     gene            complement(16413..17138)
                     /gene="hda"
                     /locus_tag="OPY25_001531"
     CDS             complement(16413..17138)
                     /gene="hda"
                     /locus_tag="OPY25_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HCS0927174.1"
                     /translation="MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQN
                     VLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGME
                     HLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLAS
                     RLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQ
                     LDHASITAQRKLTIPFVKEILKL"
     gene            complement(17209..18498)
                     /gene="uraA"
                     /locus_tag="OPY25_001532"
     CDS             complement(17209..18498)
                     /gene="uraA"
                     /locus_tag="OPY25_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCS0927175.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVMFPPAAMGAIVAVIGLELAGVAAGMAGLLPAQGQSPDTKTII
                     ISMVTLAVTVFGSVLFRGFLAIIPILIGVLAGYALSFALGVVDTTPIAQAHWFALPTF
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLVRDPGLHRSMFANGLSTII
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQIIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVHIGAAELKGM
                     ALATIVGIGLSLIFKLISLLRPEEVVLEANDAESPHQ"
     gene            complement(18586..19212)
                     /gene="upp"
                     /locus_tag="OPY25_001533"
     CDS             complement(18586..19212)
                     /gene="upp"
                     /locus_tag="OPY25_001533"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCS0927176.1"
                     /translation="MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            19625..20662
                     /gene="purM"
                     /locus_tag="OPY25_001534"
     CDS             19625..20662
                     /gene="purM"
                     /locus_tag="OPY25_001534"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001656828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCS0927177.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKKTRRSEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDAIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTAASVINGIAEGCLQSGCALVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSRVAEGDVLIALGSSGPHSNGYSLVRKIIDVSGCDPQTTLLEGKPL
                     ADHLLEPTRIYVKSVLELIENIDVHAIAHLTGGGFWENIPRVLPENTQAVINESSWQW
                     PAIFTWLRTAGNVSRHEMYRAFNCGVGMVIALSAPEADKALALLNEKGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            20662..21300
                     /gene="purN"
                     /locus_tag="OPY25_001535"
     CDS             20662..21300
                     /gene="purN"
                     /locus_tag="OPY25_001535"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCS0927178.1"
                     /translation="MNIVVLISGNGSNLQAIIDACEAKKIKGTLRAVFSNKADAFGLE
                     RAREAGIPAQALTADRFDSRDAFDRELIRKIDAYAPDVVVLAGFMRILSPMFVAHYYG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAND
                     SEDDITARVQTQEHAIYPLVIGWFAQGRLKMRDNAAWLDGRRLPPQGYASDE"
     gene            21489..23555
                     /gene="ppk1"
                     /locus_tag="OPY25_001536"
     CDS             21489..23555
                     /gene="ppk1"
                     /locus_tag="OPY25_001536"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HCS0927179.1"
                     /translation="MGQEKLYIEKELSWLAFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQGFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQSWLRHYFKHYLRQHITPILINRETDLVQFLKDDYTYLAVE
                     IIRGDTINYALLEIPSDKVPRFVNLPPETPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMESSLMELMSSSLKQRLTAEPVRFVYQRDMPAALVDVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHLWFDKEKFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKEGDDVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMIDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASGSGVQVNLLVRGM
                     CSLIPQLEGISDNIRAISIVDRYLEHDRVYIFENGGDKQVWLSSADWMTRNIDYRIEV
                     ATPILDPRLKQRVLDIIDILFSDTVKARFIDKELSNRYVPRGNRRKVQAQLAIYDYIK
                     SLEQPD"
     gene            23560..25101
                     /gene="ppx"
                     /locus_tag="OPY25_001537"
     CDS             23560..25101
                     /gene="ppx"
                     /locus_tag="OPY25_001537"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HCS0927180.1"
                     /translation="MPIYDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGADNKLSEEAMERGLSCLSLFAERLQGFSPSSVCIVGTHTLRQAQNAADFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPR
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQYRIQGWNVAMGASG
                     TIKAAHEVLLALGEKDGFITPERLDKLKSEVLKHRSFNALSLPGLSEERKAVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTAKSLANQYNIDREQAR
                     RVLETTMQMYEQWQAQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQHS
                     DLPGFNQEQQMMMATLVRYHRKAIKLDDMPRFTLFKKKQYLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLRLTTDDSHWTLCFPHDWFSQNALVLLDLEKEQQYWEAVTGWRLNIEEESS
                     PEIAA"
     gene            complement(25137..27350)
                     /locus_tag="OPY25_001538"
     CDS             complement(25137..27350)
                     /locus_tag="OPY25_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HCS0927181.1"
                     /translation="MKLNKTYINIRDKWWGLPLILPSILLPVLSSANTYALTSTGNVV
                     LFYLPLAFMLSLMLFFGWAALPGIVLAIFWRRYPQTGLYETLSVTMHFIITIVLSWGG
                     YRVFSPRRNNVSHGDAHLLFQRMFWQVFCSATLFLVIYQFAAFVGMYESKASLMGVMP
                     FNINTLINYQALLVGNLVGVPLCYFIIRTLRNPLHLRGYYQQLKLQIDSKATKKEIVI
                     WLAVLTTLMFILCMPLTDNSSIFSTNYTLSLLLPVMLWGAMRYGYKFISIIWAVVLIT
                     SIHYYQRYMPWYSGYDTQLAITSSSYLVFSFIVNYMSVLATRQRVVSGRARRLAYLDP
                     VVHLPNLRALNRALKNAPWSTICFLHVPGLELLGKNYGVMLRIQYKQKLSHWITPMLA
                     SNECVYQMSGHDLVLRLNTEAHQQRIEALDKHIKQFRFIWDGLPLQPPVGVSYCCVRS
                     PVSHLYLLLGELSTSSDLSLTTNAPEDLQRRGAMHLQRDLKGRIAMMNRLQQALEHDH
                     FFLMAQPIFGVRGDVYHEILLRLRDDNGDVINPDNFLPVAHEFGLSSAIDLWVIENTL
                     RFMAASREYMPAHRFAINLSPTSVCRARFPAEVKQLLTQYQVEPWQLVFEVTESNSLT
                     NAEQAQLTLGQLQQFGCQIAIDDFGTGYASYARLKNVDADILKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKNMQVVAEYIESEEIRSVVLSLGIDYLQGYLIGEPQLLSEIQ"
     gene            complement(27447..27584)
                     /locus_tag="OPY25_001539"
     CDS             complement(27447..27584)
                     /locus_tag="OPY25_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927182.1"
                     /translation="MEDNFSIYINNKLMITKNKKTNKGCRRKVIIDLNQMLLLFNNYN
                     R"
     gene            27781..27954
                     /locus_tag="OPY25_001540"
     CDS             27781..27954
                     /locus_tag="OPY25_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311393.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HCS0927183.1"
                     /translation="MRKRHRFNTRMTRIVLLISFLFFFGRFVYSSIGAWQHHQDKKEA
                     QQSSLSVTTPGQR"
     gene            28218..28712
                     /locus_tag="OPY25_001541"
     CDS             28218..28712
                     /locus_tag="OPY25_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311394.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HCS0927184.1"
                     /translation="MPLVLFASFSLAGCQSNADDYAADVYQTGQLNAKQETKTVNIIS
                     VLPAKVAVDNTANKKTAQTFGAILGAVAGGVTGHNVGSGSGLGTTAGAVGGGAVGAAA
                     GSLVKDKTLVEAVSLTYKEGTKVYTSTQVGKTCQFTTGLAMVISTKDNETRIQPNTKC
                     PEKS"
     gene            28728..29267
                     /locus_tag="OPY25_001542"
     CDS             28728..29267
                     /locus_tag="OPY25_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HCS0927185.1"
                     /translation="MKKVILGAVLFTLSGSVLSSSLQDQLAAVAQAEQQGKNEENRQR
                     DALQAKRDQEAQQERQRQANAAAVAKQRAKAAEAERKARQAKLAAEAAQDKARDQSYE
                     DELRRLEIQKQKLALAREEARVKRENEFIDQELKSKAAQTDVIQSHADANRNLSEGGR
                     DLLQSEGKAREEKASGWFN"
     gene            29496..30185
                     /locus_tag="OPY25_001543"
     CDS             29496..30185
                     /locus_tag="OPY25_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927186.1"
                     /translation="MKDFSKYSKALGMAKFYVYAFYDTEDAAKKPFYIGKGKSERCLD
                     HIKYNDDSPKSERINHLLKTGNLGIDILRHGMDEATAKLVEATCIDLLGVGELTNKVR
                     GSSSLMGRITLDELNHLLLKQETEIAPEHAGLAFLLNSTYKSGMSALALYEATRGVWA
                     KVPKDENLQFAYATYGGLVMEVYEIQCWLKAGSQQYFTRELVIPPPKPTVQNLLDESH
                     HQKSEDYTLAS"
     gene            complement(30508..32085)
                     /gene="guaA"
                     /locus_tag="OPY25_001544"
     CDS             complement(30508..32085)
                     /gene="guaA"
                     /locus_tag="OPY25_001544"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCS0927187.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEG
                     SNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(32155..33621)
                     /gene="guaB"
                     /locus_tag="OPY25_001545"
     CDS             complement(32155..33621)
                     /gene="guaB"
                     /locus_tag="OPY25_001545"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCS0927188.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLHEVKALTERNGFAGYPVVTEDNELVGIITGRDVRFVTDLNQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDNFHLLGMITVKDFQKAERKPNSCKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATGAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVSDAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCATI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            33782..35131
                     /gene="xseA"
                     /locus_tag="OPY25_001546"
     CDS             33782..35131
                     /gene="xseA"
                     /locus_tag="OPY25_001546"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCS0927189.1"
                     /translation="MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIAESM
                     QPAGEGLLQQKYEQLKAKLHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANTRGECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQS
                     AQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALERLRQRMGFALEARI
                     KQATQRQQRVSQRLSQQNPQPRIHRVQSRIQQLEYRLTENIRSRLSEQRERFGNAVTH
                     LEAVSPLATLARGYTVSTTTDGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT"
     gene            complement(35293..40249)
                     /locus_tag="OPY25_001547"
                     /pseudo
     CDS             complement(35293..40249)
                     /locus_tag="OPY25_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835061.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
BASE COUNT         9765 a        11179 c        10362 g         9189 t
ORIGIN      
        1 atgacttcga taaaatcttt ccagttcccc agttccccag ttccccagtt ccccagttca
       61 cgttcaatca taatagcctc tcttattatt atgggtattc tacgtagtta gcggtataga
      121 gagaagttca tttaaccgat tgttgcgata tcctctggtt atgctgtcta tgatattact
      181 atggcgctgt agccgtaaat tttatgtgac ttactgcaat atttagcaac attaatacct
      241 tttctactac tttatcaaat cgggttaaaa aacaatcaat tgcatgtgcg caaaatagga
      301 ttttcctcac gaattataaa caagccacat ctggaacgtt ttggaatcat tattcacatt
      361 cactcaacaa tgttatattg attgccgatc agcgctggat aaataaccat taacagccac
      421 acttattatc ccgcagacga tactattgat tatttattcg aatttcgcgt taaaggattc
      481 aatatgatta ccctctatgg cattaagaat tgcgacacga tcaaaaaagc gcgccgttgg
      541 ctggaggagc atggcattga ttatcgtttt cacgattacc gtgtggatgg catagacctc
      601 cctcttctta atacctttat tgccgaactc ggctggcagc ctttactgaa tacgcgcggc
      661 acaacatggc gcaaactgga tgaaggccac cgcagcggga ttaccgatgc cgactccgcc
      721 gctgctctca tggttgaaca gccggcaatc atcaaacgcc cattgctctg cgcgcccggg
      781 aagcctatgc tgcttggttt cagtgaatcc cgttatcagc agttttttga tgaggtgtag
      841 tctatgtcgt gcccggttat tgagctgaca cagcaactta ttcgtcgccc ctccctgagt
      901 ccggatgacg taggctgtca ggcattaatg attgaacgcc tgcgtaaaat cggttttacc
      961 attgagcata tggattttgg cgacacgcaa aatttttggg catggcgtgg gcgtggcgaa
     1021 acgctggcgt tcgccgggca tactgacgtc gtaccggctg gcgatgtcga tcgctggatc
     1081 aatccgccgt ttgaacctac gattcgcgac ggaatgttgt tcggtcgcgg cgcggcggat
     1141 atgaaaggtt cactggcggc catggtggtg gctgctgaac gttttgttgc acagcatcct
     1201 catcaccggg gccgcctcgc atttttgatt acctctgatg aagaagccag cgcaaaaaat
     1261 ggcaccgtaa aggtggttga agcgctgatg gcccgtaacg agcggctgga ttactgtctg
     1321 gtcggcgaac cttccagtac tgaaattgtg ggcgatgtcg tcaaaaacgg gcgtcgcggt
     1381 tccctcacct gtaacctcac tattcatggc gttcaggggc acgttgccta tccgcatctg
     1441 gcggataacc ctgttcatcg cgccgcgcct tttctcaatg aactggtcgc tatcgagtgg
     1501 gatcggggca atgacttttt cccggccacc agtatgcaga tagccaatat ccaggcaggc
     1561 accggcagca ataatgtcat tcccggcgaa ctgttcgtgc agtttaactt ccgttttagc
     1621 acggagctga ccgatgagat gatcaaagaa cgggtacatg cgctgcttga gaagcatcag
     1681 ctacgctata ccgtagactg gtggctttcc ggtcagccgt tcctgaccgc acgcggaaag
     1741 ctggtggacg cggtggtaaa cgccattgag cactataatg aaattaaacc gcaattactg
     1801 acgacgggcg gtacgtccga cggacgtttt atcgcccgta tgggagcgca ggtggtagaa
     1861 ctggggccgg tgaacgccac cattcataaa attaacgaat gtgtgaatgc cgccgatctc
     1921 cagctactgg cccgtatgta tcaacgtatt atggaacagc tcgtcgcctg atgagcgttc
     1981 cggtaagagg aaataagcat ggactggctg gcaaaatatt ggtggattct ggtattggtg
     2041 tttctggtag gcgtactgct gaatgtgatc aaagatctca aacgcatcga ccataagaaa
     2101 ttccttgcca acaaacctga gctgcccccg catcgcgatt ttaacgataa gtgggacgat
     2161 gaagacgact ggccgaagaa agatcagccg aaaaagtaac cggataacat gccggacagg
     2221 tatcgctatc cggcatggtc cccaccgcct ggcattacgt cgcgcaaacg ctgcgttcgt
     2281 ccggcatcca acgcaattag cgcctgcgcc gcctgcgcac gctgcaacgc cagcagagct
     2341 ttacggcctg aaatgcgtag ccgggcgcac agttcggcat cgctggcttt ttcctccagc
     2401 cgccctctca gcgccggcaa tggcaatgcg ctgtattgca gtaaacgatg caggcaacct
     2461 aacgatgtca gtagcgggcg gtgcgcgaac gcaaaaccga ccagctcacg ccagtcttca
     2521 tcattaagcg cctgttcgcg caacgccgcc agcggtatcg cctcgccgtt ccactgcgtc
     2581 aggatatccg catcgcggcg caaacgtcgg tgttcctgtt gcgccagccg ttgtcccgcg
     2641 tcgctcagcg gcaataacgc catcgccgta tagcaaccgc tgctcgcctc ccgatggctg
     2701 cccatccgta ccagcacaaa gccgcagcgt tgccagaagc gccacagctc cggcgtatag
     2761 ccgaagctga cggaaagata atcacactgc gccgcctgct cgcacgcgca ggcaatcaac
     2821 tgctgaccga tgccttcgcg ctgacgggcg gggtgcaccg cgatacggct tacgcgacgc
     2881 ccgaccagcg tcgcggctaa agggtcgcta ccgtgcgccg ccagcgactg cgccaccaga
     2941 tttccacgcg gacgccggaa accgcaccat acagcctgac tgagctctgc ggataacccg
     3001 ccctcttcga ccagccagag ggcgcccgcc acacggttat tcgccgtagc ctgcaagaaa
     3061 tgctgtcctg gcgcatccat cattcggcgc agatccaacg gcgaagtacg atagtgcgcc
     3121 cccgacagta actgatacac agccctcggc aacgcgggcg tcttccccca ggcctgctgg
     3181 taaaatgccg agattgctat cccgccatgc ggcgcctgcg caaacgcttc atcgtcgaat
     3241 atcagcgcct cgctgacgat attttccagc gggcattctg gcgcccagcg gacaggctga
     3301 cgaagcgtaa agcggtgaag ctgcggaaaa cgggcgcaaa acttaagtaa aaaaccgcgt
     3361 ccggtgcctt cgtagccctg aacggtggtg gtgagtagta tgcggggaaa gcgcgaaacc
     3421 agttgcagca gcagcggcgc ggggattgcc gccgcctcgt caaccaccag ccagtcggct
     3481 cttgccccgc tcgccagcag cgcatccggc gccataaagc agaaccgctc accggcaaac
     3541 gctgccagga tatccgttgc cgttttcgcc ggtgcggtca cgatagccgt gcccgccatc
     3601 tgtgagatga attgcccggc cagcgccgat ttgccgcgcc cacggggggc aatcaccgtc
     3661 gccacgccgg gcggcatttc acgtaaacgc gataagatag ccgcctgctc cggctgcggc
     3721 tcgccggtgg cgggtcgcca gcgttcgcgg gaaggataag atggccagca aaacggctgg
     3781 cgctgtcgcc aaagcagcgt ttgcggatcg cgggaaagag tccgtttaag atgctgtgca
     3841 aactgcggtg tggggatagg ctgcgcgcag tcgctccagc gcagtgaatc ggtatcaggc
     3901 cggctttccc acgtctcata cggcggcatc agcagaagca gccaacttcc ggcctgcaag
     3961 gtcccgctca gggcggcaaa cgctgcggcg tcaaagccct gccaggcatc aaatatcgca
     4021 tgacgaaatt cacggcccag cagcgtttgt aacgcctgtg gcgtacagcg cggctgggcg
     4081 ggcgcgtcag gcgcgaccca ccagtcaccg ggcaatacag cgcgtatcgc ctcggcccgt
     4141 tcccggcacc acgccgcatc gccgctgatg accagtaaac ggcgaatgcc ttcctgtgtc
     4201 atttgcgacg ttaacgcccg tagcgcatcg atatcagaca tccctgcccc agtttatcaa
     4261 aagtttttac caaacgtatt acattgcgcc gggtcaccgc tgtcaaatcc acgcttaaac
     4321 cagctgtagc gctgttctga ggtgccgtgg gtaaaactat ccggcaccac gcgcccctgc
     4381 ccctgttgct gtaagcgatc gtcgccgata gcctgtgcgg cattgagcgc ctcttccaga
     4441 tcgcccgcct ccagtacgcc ttgctgctgc atactgtgtc cccacacgcc ggcaaagcaa
     4501 tccgcctgta gctccatgcg caccgaaagg cgattcacct ccgtttgcga cgcgttttgt
     4561 tgtaactggc gtactttcgg ctcaatgcct aacagttttt gtacgtggtg gccgacttcg
     4621 tgggcgataa cataaccctg ggcaaaatca ccgtccgcgc ccagcttatt tttcataaca
     4681 tcgtaaaatg agagatcgat atagacggtg ccgtccgccg ggcagtaaaa cggccccatc
     4741 acggactgac ccgcaccaca gccggtacgc gtcataccac ggtacatcac cagttttggc
     4801 tgctgatagc cgcgccccat tttttgaaag agttgccccc aggtatcttc ggtcgtcgcc
     4861 agaatcaccg aggtaaattt tgccgcttca tcatcattgg ggcttatcga acgcgtcgac
     4921 tgctgctgcg aaaccggctg accagtcaac agaccggtta aatccacccc atagtaccct
     4981 gcgaccacca ccaccaccaa cagaatgatg ccgcctttcc cgcgcggaag acgaaagcca
     5041 gggccaccca gcgaggggcc gcctggccga ttacgtctgt cctctacatt gttactttca
     5101 cgacgccctt gccagcgcat aatcacctca ttctctcttt gttatacaga tgatcgtagg
     5161 cggtcaggcg caggattacc acaggtaaac gctatcagaa tgaggaaagg atgataccgg
     5221 agagcggttg cccccccggt cagaagcgga attaatctaa tttcacgccc aggcgatgcg
     5281 caacggcttc ataggcttca atcagaccgc ccaggctctg gcggaagcgg tctttgtcca
     5341 ttttgtccag cgtctcttta tcccacaggc ggctaccgtc cggtgaaaac tcatcgccca
     5401 gcaccacttc gcctttatac aggccaaact ccagtttgaa atccaccagg ataagacccg
     5461 cgtcatcaaa cagttttttt agtacgtcgt tggctttgta ggttagctct ttcatacgcg
     5521 ccagattttc ctggcttacc cacccgaaag tttcacagta ggaactattc accatcgggt
     5581 cgtgcagcgc gtcgtttttc aggaacagat cgaagatcgg cgggttaagc tccatgcctt
     5641 cttccacgcc cagacgcttg accagcgacc ctgccgcacg gttgcgcacc acacattcaa
     5701 ccggcaccat ctccagcttc ttcaccagac actcggtatc agacagcaaa cgttccatct
     5761 gggtcgggat gcccgcctcg gccagtttgg tcataatgaa atggttgaat ttgttattta
     5821 ccatgccttt gcgatcaaac tgttcaatgc gcgcgccatc ccctgctgac gtatcattgc
     5881 ggaattcgag caccaacagg tccgggtttt ccgtgctgta tacggttttc gctttaccac
     5941 gatacaactc agcttgcttt tgcatcttta acactcctgg gtgtgaatta acgataagta
     6001 ttcatttcct gctacgcctg ccagagacgc cggcctgtaa ttgtggtgcg aaatagcggt
     6061 taaatcgcgt ttttgtaccg acgcacacgt ttgcgtatct tatcagaaaa aagggccgga
     6121 ttgctccagc cctgttaaat tacttgttga acgcagcctg gaagacggca accagcgcgt
     6181 cgttctggct ttgcgtcaga gtatgcccct taggatcgat aaactgcaag ctgctgcggt
     6241 tatctaaatc gccgacctgc aatttatagt ctccggatgc caggcccggg tcgctagcgc
     6301 ccagatcccg ccagtcgctg tcagacaacg gtttgtacgt taccgccatg ctgccctgag
     6361 agcgagtgct gtcggtgact ttcatgccca ctttttccag cgcggccggg agacgctgcc
     6421 acacgaggtt gaacggaccg cgaacgacca gcataggtaa accggtatca tcagcggcgc
     6481 tctgcacatc catcgttgcg gcggaacggt tctgcgcggc atttgccgca tccgtagcgg
     6541 tcttatccag accggcggaa atgacgttca tcatttcagt gctatagcgc tgcagcgacg
     6601 ccgcatcagc gaccggcttg ccagcctgtt ccagattaac cagttttacc gttaccgcct
     6661 gctgatagcc ctgcggcttc accgagattt gataacgtcc gcgatactgt tcgtcttcat
     6721 ccaggcggtt ccagctcacc caatcggtcg tcagggtctg gctggcatcg tcacgttttt
     6781 caatcggata atttttcgcc tgaatcacgc tgacgacttg cggccacagc gtgctgctac
     6841 ggccattttc caccaatagc gtagcggtat cgccagagaa ctgggtacgc gcgccgctca
     6901 ctaacgctaa cggctgcgcc ggcggacgga tatccaacgc cttaccaacc gcgccgctcc
     6961 ccttcgtgac cggaataacg tagtcgccgg tcgttatcgg cagaatcatt cctgccgggg
     7021 cgtgaagttc agcaagcggc gcggcatcca gataggattc atcgccgctt acctggcgct
     7081 tgtagcgcga atcggaacta caggcagcga gcagcaaaac aagcgaaaca cccgcaacct
     7141 tcgccaggcg cgacttttgt actgagtaag ccatcaaatc tccctaaact ttacagcagg
     7201 ccagcatgct gaagcgctgc tttgacgatg tcacgaccat ggtcggtgat aggcgtcatt
     7261 ggcaggcgca gcgtgtcggt cgccacaaga cccaatgcct tacatgccca tttcaccggg
     7321 ataggattgg gttcgacaaa tagtttgttg tgtaacggca tcagacgctg gttgatagcg
     7381 cgcgcctcgg caaattgccc ttccgccgcc agtttgcaca tgtcagccat atcgcgcgcc
     7441 gctacgttag cagtaacgga aatcacgcca tgaccaccca gttgcataaa gtccagcgcg
     7501 gacgcgtcat cgccgctaag cagaataaaa tcgtctgaaa ccagctcttt gatctggtga
     7561 acgcgggtta agttccctgt cgcctctttg atagcgataa tattttttat ttccgccaga
     7621 cgacccacgg tttccggcaa catgtcgcaa ccggtacggg acggcacatt atacagaatt
     7681 tgcggcaagt cagtgtgttc cgcgatggct ttgaaatgct ggaacaaacc ttcctgcgtg
     7741 gggcgattgt agtacggcgt taccgtcagg cagccaacaa tgccgctatc gttaaaacgc
     7801 tgcgtcaggc taatcgcttc cgcggtcgcg tttgcgcccg tgccagcgat aaccggaata
     7861 cgtccgtcag ccagttccag cgtcatcatc acgacatcgc catgttcatc atggcttagc
     7921 gtggcagact cgccggtggt gccaaccgaa acaatcgccg aggtaccgtt ggcgacatga
     7981 taatcaatga gttttttcag gcaagaccta ctgacgttac ctttctcatc catcggcgta
     8041 acaagcgcga caatacttcc cgtgaacatg ggccatcctc tgtgcaaaca agtccctcaa
     8101 tggtacgttt ggtatgacaa taaaagcaag cgaccaaagc cgttctgatt gttgtatgca
     8161 ggtttttttt atggtttcct taagattacc tcaccgctca aaggaataac tggtttgaca
     8221 ccgtcatcac aacactattt ggttatcact gcgctgggcg ccgacaggcc cggtattgtg
     8281 aataccatta ctcgccatgt cagcagttgc ggctgtaata tcgaagacag ccgactggcg
     8341 atgctgggcg atgaattcac gtttattatg ctgttgtccg gcacgtggaa cgcgattacc
     8401 ttgattgaat cgacattgcc gttaaaaggc gcggagctgg atctgctgat tgtgatgaaa
     8461 cggacgtccg accgcccccg cccggcaatg cccgcgacgg tatgggttca ggttgaggtc
     8521 gccgactccc cgcatttaat tgagcgattc accgcgctgt ttaatagtca tgaaatgaat
     8581 attgcggagc tggtctcccg cacgcagccg gctgaagatg ataaagctgc gcaattattt
     8641 attcaaatca ccgcacatag cccggcgtcg caaaattccg caaatattga gcaagccttt
     8701 aaagcactat gtacagaact caatgcgcaa ggcagtataa acgtcgtcaa ttactcacaa
     8761 catgatgaac aggatggagt taagtaatga atccactgaa agccggtgat atcgcaccga
     8821 aatttagctt gccggatcaa gacggggaac aagtaaattt gaccgacttc caggggcagc
     8881 gcgttctggt ttatttctac ccaaaagcca tgacacccgg ctgtaccgtg caggcctgcg
     8941 gcttacgcga taacatggac gagcttaaaa aagcaggcgt ggacgtgctg ggcatcagca
     9001 ccgataaacc tgaaaaactc tcccgtttcg ctgaaaaaga gctgctgaac tttacccttt
     9061 tgtccgatga aaaccatcag gtgtgtgaac agtttggcgt ctggggcgaa aagtcgttta
     9121 tgggcaaaac gtatgacggc attcaccgca tcagcttttt gattgacgct gatggtaaga
     9181 ttgagcacgt ctttaatgat tttaaaacca gcaatcacca tgatgtggtg ctgaactggc
     9241 tgaaagaaaa cgcgtaaaag cctcaggccg cgctgatgtg cggcctggaa agggaatgcg
     9301 ccgtcaggct tgccgcgcca gacgccatat cgccgccaca ttgcgcgccg acaggctcag
     9361 gttatattcc gcctcgtgta aggcttccgg cagcgtaacg atatgcgaca aaatcgatag
     9421 cgccgcatcg ataccctgct gatacacaac gtgatgatcg tgttgcagcc caccggcgag
     9481 cgcgataacc ggtttatgat gccgcttcgc cactctggcg acgccaatcg gcgtcttgcc
     9541 gcaaatactt tggctgtcca gccgcccttc tccggtaatc accagatcgg catctttaac
     9601 cgcctgctca agctgtagcg tttccacgac aatctctacg ccggcgcgta attccgcatt
     9661 gagcaaccct aaaagcgcgg cgcccattcc gcctgccgcg cccgcgccgg gagcgttaat
     9721 cacctcacgt cccgttgcct gataaatatg tcggccccag ttttccagcg ccgcgtccag
     9781 ggagttcacc atttccgctg tcgccccttt ttgtgggcca aagatggccg atgcgccctg
     9841 gggaccacac agcggattgt tgacatcaca cgccacggtt atcgatacct tacgcagcaa
     9901 tgggtgacaa ccggacaaat cgatagacgc cagcgccgcc agcgcctcgc cgcccggaga
     9961 aagcgagcgc ccctgtttat cgcgcaatat aacgccaagc gcctgcatca tccccgcgcc
    10021 gccgtcattc gtcgcactgc cgccaattcc cagaataata cgctttacgc cacgctccag
    10081 cgccgcgacg attaactcgc cggtgccgta gctggtagta ttaagcgggt tacgcaattc
    10141 aggcgaaacg tgatgcagcc cggatgccgc cgccatttca atcacggcgg tatcgctatc
    10201 gcccagcatt ccccaacgcg cggttaccgg ttgcccaagc gggccttgta cccactggtc
    10261 aacataacgc ccgccgctag cttccaccat tgattgcacg gttccttccc cgccatccgc
    10321 catgggcacc ttaacgtagt cggcgtcagg ataaatttcg cggaacccct tttctatcgc
    10381 ctcagcgacc gccattgcgg acaaactttc tttaaatgaa tcaggagcaa taacaatttt
    10441 catagggatt atcctgcaaa accaaagaaa ccgaacatca gagtagaaat aaaggtaatg
    10501 gctaacccca ccagcgtttc atacggcatt agctttaaac gttcatgaat ttgcatattg
    10561 acgctgccgc ccgtcgcgtg gaaaaagctg ccatgcggca gatggtccag caccgtggcg
    10621 cccgcatgga tcatagcggc tcccgccagg gcggaaacgc caagttcaag taacgtggga
    10681 gagaaaacgc cggacgccac cgccgttccc gctgtggttg aggccgtcgc cattgacatc
    10741 atggcgccag acacgggcgc cagcagccag gacggcaatc ccgaagcggt gaggccatga
    10801 atcaggacat ctttaagttc ggaattagcg ataatgccgg ccagcgtacc ggttcccagc
    10861 aacataatag cgacaggcgc catacgcatc agaccggcga ccatgtactg gttacagtgg
    10921 cgcgcgcgtc ccatcaacag cagaccgacc aatcccccta cgggcagggc aattaacggg
    10981 tcaatggaaa tgccgacaaa cggacggaga gaaagcagga aaatagcgac cagcggcgcg
    11041 ctaatcgcca ccagaaaacc gggcctggcg acagagtcat catggtgagt cacttcatga
    11101 tcggcgacgc ccgcgccttt attattcagc cgtttcgcta acagataggc gataataagc
    11161 ccaacgatgc ccggaaccac gcccgccagc ataatagagg taagaggaac atgaaacgca
    11221 tcggaggcgg caatagcgtt cgggttaggt gacatcacgt tacccgcttt gccgccgccg
    11281 accatcgcca gcagaatagc gctttttgac aggcctgcat tacgcgcaat cgacagcgca
    11341 atcggcgcga cggtaatcac cgccacatca ataaatacgc cgacggcggt caaacatagt
    11401 gtggcaatgg ctaatgccaa taatgcccgg gtttccccca ctttgcggac aatcgtctca
    11461 gcaatcgtat tcgccgcccc ggactcaatt aatacgcccg ccagtacgcc tgcggccaga
    11521 atacgcaata cggcattaac gatgccctgc gcgcctgaca ccatcagcga cacggtttgc
    11581 agaagatcgg cgccgccaat caaaccgccg accagcgcgc ccgccatcat gccgtaggct
    11641 ggcgacactt ttcttaaaat taatacgatg gccacaacca atgcggcaat ggctcccaag
    11701 gtggatatcg acgtcatata ctgcgcctcc tttaacatgg agcgcgcagt atggaaaaaa
    11761 ccgcctaaaa atccgctgga gctttcaaca aatttcgatt cgaccaagca gcggtaactt
    11821 gtcggacgat acagattcgg cctgaagctc cataccgata taaagccaaa gcgtactttt
    11881 taactcgttg atttttatgt gcgtaatatc ctcacagcgc tgtaagcgat agcgcaatgt
    11941 attcacatga atatgcaatg ctttggccgt ttgcgtcagg tcacaattat gttcaaacca
    12001 agtccgcagc gtctgttgca atacgccttt cgcgtcatgt tgcaccagtt gcagccacag
    12061 acgcgataac tcctgcactt gccaactttc agacagcccg cttagcagcg cgggaagcgc
    12121 gtggtcatga taaaaaatgt actggctgcg cagcttttgt cttttcgcca tcgcctgcgt
    12181 ggctctcgct gtgagcaaag atcggtgcaa tcccgtctcg ccggcaaaat agcccccaac
    12241 caaaatacgg ctaaagcccg atgatgcagc ccatgattta aaaatctgca attcgcccat
    12301 ttcctggcgg gtattccact ttccctcttt taacgtgata ggcttaataa tgattaattc
    12361 attaaattcg gtaaacgtca ccaaatggtt gcgcgcgtga ttctcgaaat aatccattac
    12421 attgcgcagc gcttcgcgat ccggctggga aagttcaata atcagcacca ctctgggaac
    12481 cgccagatca atgcccagat aggccgccat ggagcgcaac gactctgttg aattttctcg
    12541 caaaatcaat tggttgatca gctcttcgcg atagcgttta tcccattgtc actgttcgat
    12601 cagcaccata tgctcgatca ccagctccgc cgccatttta accagctcgg catacgcgcg
    12661 aacctcctcc ggttcgccgg taatgccgac cacaccgata agctgttcat gaaaagagat
    12721 gggaagatta atgccggatc gcacgccttt aagctgattg gcggtagcgg aatcaatttc
    12781 tacaatacgg ttttccttca gcgccagaat ggccccttcg tgacgctggc gaagccgcga
    12841 aggttcgcca gacgcgataa tgacgccatg ctcatccatg acgtttaccg agtaaggaat
    12901 aattttcatg gctcgctgta caatttgccg cgcggtatac cctttcaagt aatgttttct
    12961 caacacactc attccctgtt tcgttatcgc ttcacattaa aaaagcaatc tcgcatcaat
    13021 gatgtcactt attaacgaat ttctcagaag aatgcttagg ctaagtcacc aaattttggc
    13081 ggctttacag cgagaatttt gtaggttccg acaataaaaa tgccgcaaca cggtgcggca
    13141 ttaaaaaaaa gagcggcttt ctaagcgctt gaccctcatc aggcgtgcgc aaaatggcgg
    13201 cagggcacta tgatgtcgtt cacgctttac aacttttgta cagaccgctc aggatgaggc
    13261 atccgtcacc tgaccatccg gccaggcatg gacaacggct ttaatcagcg tcgccaatgg
    13321 aatggcgaaa aatacccccc agaatcccca cagaccgccg aaaatcacca ctgacagaat
    13381 aatcaccagc ggatgcaaat tcaccgcttc ggagaaaagt accggtacca gcaaattgcc
    13441 atccagcgcc tgaataatca gataaacggc aaaacagctc cagaattccg tccccagacc
    13501 aaactgaaac agcgcgacgc ccaccaccgg aattgtcacc acaaaggcgc cgatataggg
    13561 gatcaggacc gaaaagccca ccagtaccgc caacagtagc gaatagttga ggccaaacaa
    13621 caaaaagccc agccaggtcg ccacgcccac cactaccatc tccagcactt ttccgcggat
    13681 atagttggtg atctgctgat tcatctcatt ccacacctgc cccgccagcc cgcgattacg
    13741 cggcagcacg cggcgcacgg cattcagcat ctgctcttta tcttttacca ggaaaaagac
    13801 catcagcggc accagcacca gatataccgc cagcgtcagt agcccgacta acgaagccag
    13861 cgaatatttc accaccgaat cgcccatgtt aagcatccgg gtacgcatgt tttccgccat
    13921 cgcatcaata atgcccgcat ccatcagcgc cggatagcgt cgcggcaagg tcgcggcaaa
    13981 atcggacagt ttattcagca taccaggcat atcacgaatc aggtaaatac cctgctgcca
    14041 ggcaatcggc atcaccacaa acgccattaa taacagaatg ccgacaaaga ggataaggac
    14101 aatggaggct gcccagcgcc gggaacagcc aatcgcctgc aggcgcgccg tcggccactc
    14161 cagcaggtag gccagtacga tagcgaccag cagcggcgct aacaggccgc taaagaaaaa
    14221 gaggatgcta aaaccagcca ccagaatgac cagcaaggca atcgcctccg gatcgctgaa
    14281 gcgacggcga taccattgca ttaacatttc gagcataaaa cccttcccag aactcaactg
    14341 cgggattgtg atgccgaatt gtatcgaaat gtcacaaaaa agacttcgct ttttatcgtt
    14401 gattcaggaa actaaaatag tgagtctgtg ctcatcacag ttacacttat gaagtgtcgg
    14461 agcgtggaac gatatttcac gacgttggtc aaagggctat ctcaaaacaa caggatagag
    14521 gttatgttca ggcagttgaa aaaaaacctg gtggcaaccc tcattgcagc attggctctc
    14581 ggtcaggtcg cgcccgcatt tgccgaccct gccgacacgc tgcccgatat gggaacctcg
    14641 gcaggaagca cgctttctat tggacaagag atgcaaatgg gcgactttta tgtgcgccag
    14701 ctacgcggca gcgcgccgtt aatcaacgat ccgctgctgg tgcaatacat taacgcgctg
    14761 gggatgcgtc tggtctcgca cgcagactcc gtcaaaacgc ccttccattt tttcttgatc
    14821 aataatgacg aaatcaacgc gttcgcgttc tttggcggca atgtggtgct gcactcggcg
    14881 ctttttcgct acgcggataa cgaaagccag ctagcttcag tcatggcgca tgaaatttcc
    14941 cacgttacgc agcgccatct ggcgcgcgcg atggaagatc aaaagcgcag cgcgccgctt
    15001 acctgggtgg gcgcgctggg ttccattttg ctggccatgg ccagcccaca ggccggtatg
    15061 gcggcgctaa ccggtactct ggcgggaacg cgccagggaa tgataagttt cacccagcaa
    15121 aatgagcaag aggccgaccg tattggtatt caggtactgc aacgcgccgg atttgaccca
    15181 caggcgatgc cctctttcct cgaaaaactg ctcgaccagg cgcgttactc cacgcgaccg
    15241 cctgaaattt tgctcactca ccccttaccg gaaagccgcc ttgcggatgc ccgcaaccgt
    15301 gccaaccaga tgcgcccggt cgtggtgcaa tcttccgccg acttttattt cgccaaagcg
    15361 cgcgccctgg gaatgtacaa ttccggacgt aaccagctca ccagcgacct gctggatcag
    15421 tggtctaaag gcaacgtgcg tcagcaacat gcggcgcaat atggccgggc gttgcaggcg
    15481 atggaagcga gcaagtacga tgaagcgcgc aaaacgttgc agccgctatt aagcgcagag
    15541 ccgaacaatg cctggtatct tgacctcgcc accgatattg acctggggca gaaaagagcc
    15601 aacgacgcga ttaatcgcct gaaaaatgcc cgcgatctgc gcgttaatcc tgtgctgcag
    15661 ttaaacctcg ccaatgcgta cctccaggga ggccagccga aagcggcgga aaccattctg
    15721 aatcgctaca cctttagcca taaagatgac ggtaacggct gggatctgct tgctcaggcc
    15781 gaagccgcgc tgaacaaccg cgatcaggag ctggcggcac gcgctgaaag ttatgcgctg
    15841 gcgggacgac tggatcaggc aatttcactg ctcagcagcg ccagcgccca ggcaaaactg
    15901 ggtagtcagc aacaggcgcg ttacgatgcg cgtatcgacc agttgcgcca gttacaggaa
    15961 cgcttcaagc catacacgaa aatgtaatcg ccgtttatta gccggatggc gtcacaagga
    16021 gaactcatga ccgacacgat taaaatctac cataacccgc gctgctcgaa gagccgcgac
    16081 acgctgaacc tgctgaaatc taacggcgtg gaaccggaag tggtgcttta tctggatacg
    16141 cccgccgatg ccgccaccgt gcgggaactg ctgcgtatgt tgggcatgtc cagcgcgcgc
    16201 gaactgatgc gccagaaaga agatctctat aagacgcttc acctggcgga tagccagcta
    16261 agtgaagagg cgttaatcca ggcgctggtt gaacacccta aactgatgga gcgccccatt
    16321 gtagtggcaa atggtcaggc gcgtattggc cgaccgcctg agcaggtgct ggacatcctc
    16381 ggttaaccgt taaacgccgc cgtcgcggcg tattacagtt tcaggatctc tttgacaaac
    16441 gggatcgtca gttttcgctg ggcagtgatc gacgcatgat cgagctgatc cagcgtcata
    16501 aacagcgtgc gcatttcgcg atcaagacgt ttgagtaaaa accgtccgac atcttccggc
    16561 agttcaaacc cccgtaatcg ggcacgcaac tgtagcgcct gaagtttgtc ttcatcggaa
    16621 agaggctgga gtttatagat ttgcccccag tccagacggg aagcgagatc gggtaagccc
    16681 agatttaact gtcttggcgg acgatcgccg gtgatcaata accgcgtctt accggactcc
    16741 agaatgcggt tatagagatc aaagatggcc atctcccaca gttcatcgcc agcgacgcac
    16801 tcaatgttat caatacacac cagcgagagg tgttccatac cgtcgagcac ttccggcacg
    16861 aaccaggtgc gtttatcgag cgggacgtag cctaccgcat ctccacgctg cgacagttca
    16921 gcgcaggcgg cgtgcagcaa atggctgcgg cccgcgcctt cacgcgccca aaggtagata
    16981 tatccactat gttcctggcg caacacgttt tgtaacgcgg ccagtagaga ggcgttatcc
    17041 cccggccaga aacttgcgaa agtttcgtcg tcaggaagat aaagtggcaa agagagctgt
    17101 gccggtgtgt tcagagatac ctcaacccag gatgacataa aatcgcgctg agtttaccac
    17161 ataattcccg tgagatagaa ccgggcagca tcgctgcccg gcaacccgtt actgatgcgg
    17221 agactccgca tcatttgcct ccagtaccac ttcttccgga cgcaacaggc taatcagttt
    17281 aaaaatcagg ctcaggccaa tcccgacgat ggtcgccagc gccatccctt tcaattctgc
    17341 cgcgccgata tgcactttcg cgccgctaac gccgatgatc aaaatcaccg aggtgaggat
    17401 caggttttgc gctttgttgt agtcgacttt cgattcgatc aagacgcgaa tccccgacgc
    17461 gccgatgacg ccgtacaaca gcagcgagac gccgcccatc acgggtaacg ggataatctg
    17521 aatcgccgcc gccagtttgc cgacgcagga aagcagaatg gcgaaaatcg ccgcgccgcc
    17581 gataacccag gtactgtaaa cgcgggtgat cgccatgacg ccaatatttt ccccataggt
    17641 ggtattcggc gtggagccga agaaaccgga aatgatcgtc gacagtccgt tagcgaacat
    17701 cgagcggtgc aaaccgggat cgcgcactaa atcttttttg acgatattcg ccgtcaccac
    17761 cagatgaccg acatgctcgg cgatcacgac caacgccgcg ggcagaatcg tcaggatcgc
    17821 aaaccattca aaacgcggcg tatagaaggt cggcagcgca aaccagtgcg cctgggcaat
    17881 cggcgtggta tcgaccaccc ccagcgcgaa tgacagcgca tagcccgcca gcacgccgat
    17941 caaaatcgga atgatcgcca ggaaaccgcg aaacagtacg gagccgaaca ccgtcaccgc
    18001 cagcgtgacc atggagataa taattgtttt cgtgtccggc gactgccctt gcgcaggcag
    18061 caatccggcc atccccgccg cgacgccagc cagctccaga ccgatgacgg caacgattgc
    18121 gcccattgcc gcaggcggga acatcacatc cagccagccg gtgcccgctt ttttaacgat
    18181 gaaagagacc agacagaaca acacgccgca cataataaaa ccgcccagcg ccacttcata
    18241 acccagcggc aacaacagta ataccgggga aataaaggca aagctcgatc cgaggtaggc
    18301 aggaatttta cctttgcaga taaagagata cagcaacgtt ccgataccgt taaacagcag
    18361 caccgtcgcg ggattgatat gaaacagaac tggcaccagc acggtcgcgc caaacatggc
    18421 gaaaaggtgc tgtaaactaa gcgggattgt ctgtaaaagc ggcggtcttt cactcacccc
    18481 gatagcacgg cgcgtcatag tgttttcctc taagtgtgtt tgttattagt ggttttattc
    18541 aaaaaaaagc cgactcttaa agtcggcttt taattattta ttcacttatt tggtaccaaa
    18601 aatcttatcg ccggcatcgc caagccccgg aataatgtat ccgtgctcgt taagcccctg
    18661 atcgatagag gcggtgtaca gttcaacgtc cgggtgcgct ttttccagcg ccgcaatgcc
    18721 ttccggcgcg gcgaccagca ccagcacctt aatgctgcta cagcctgctt ttttcagcag
    18781 gtcgatggtc gcgatgacag aaccgccggt cgccagcatc gggtcgacga tcagcgccat
    18841 gcgctcatca atgttcgata ccagtttctg gaaataaggt actggctcga gcgtctcttc
    18901 gttacggtac atcccgacta cgctgatacg cgcgctcggt acattttcca gaacgccttc
    18961 catcatgccc aaccccgcgc gcagaatcgg cacaacggta atttttttac ctttgatctg
    19021 gtcgatttcc accgggccat tccagccttc gatggtgact ttttccgttt ccaggtcggc
    19081 tgtcgcttca tacgtcagca ggctgcctac ttctgaggcg agttcacgaa agcgtttagt
    19141 gctaatgtcg ttttcacgca tcagacccag cttgtgtttg acgagtgggt gtttgacttc
    19201 cacgatcttc atactcttct cctatcctca gatgactggc aaccacaaaa aaaatcgccg
    19261 gattataccg cttttcctct ctgacgcaac acaatgtatg cttgacctgg atcaaccaaa
    19321 agcgctgata gcggaaaagt gagtataaat cactcacgtt gaaactggcg ataaaagcta
    19381 acaaccgatt gaatcttagc aattttaagg gtgaatgacc tgtcccgacc acctgtcgta
    19441 aaccaagtgc tggatatcct tttctttttt accaacaggg aaattttcaa gcagcgaccg
    19501 aaaccatgcc aaaaaatcgc ccggataacc agggcgcaga ccacgctcgc aaacgtttgc
    19561 tttccctgtt agaattgcgc cgaatttaac ttttaccgca agaaaaaacg tggggaacca
    19621 ggcagtgacc gataagacct ctcttagcta taaagatgcc ggcgtcgata ttgatgcggg
    19681 taacgctctg gttgatcgaa tcaaaggcgt agtgaagaaa actcgccgct cggaggttat
    19741 gggcggtctg ggcggtttcg gtgcgctgtg cgcgttgccg caaaaatatc gtgaaccggt
    19801 actggtttcc ggcactgacg gcgtaggcac caaacttcgc ctggcgatgg acttaaagcg
    19861 tcacgacgct atcggtattg atctggtggc gatgtgcgta aacgatctgg tcgttcaggg
    19921 cgcggaaccg ctgtttttcc tcgattacta tgccaccggt aaactggatg tcgataccgc
    19981 cgccagcgtg atcaacggta ttgccgaagg ctgcctgcaa tccggctgcg cgctggtcgg
    20041 cggcgagacg gcggaaatgc cgggcatgta tcacggcgaa gattacgatg tggcgggttt
    20101 ctgcgtcggc gtagtcgaaa aatcagaaat catcgatggc tcccgggttg ccgaaggcga
    20161 cgtgctgatt gcgctcggct ccagcggccc gcactcgaat ggatattcgc tggtgcggaa
    20221 aattattgac gttagcggct gcgatccaca gaccactctg ctggaaggga aaccgctggc
    20281 cgatcatctg cttgaaccga cccgtatcta cgtaaaatcg gttctggaac tgattgaaaa
    20341 catcgatgta cacgctatcg cccacctcac cggcggcggc ttttgggaaa atattccgcg
    20401 cgttctgccg gagaataccc aggcggtaat taatgagtcg tcctggcagt ggcccgccat
    20461 ctttacctgg ctgcgaaccg ccggtaatgt cagccgacat gaaatgtacc gtgcctttaa
    20521 ctgcggcgtc ggcatggtga ttgcgctctc tgctccggaa gcggacaaag cgcttgctct
    20581 gctaaacgag aaaggtgaaa acgcatggaa aatcggtatc atcaaagcct ctgattccga
    20641 acagcgtgtg gttattgaat aatgaatatt gtggtgctga tttccggcaa tggaagcaat
    20701 ttacaggcga ttatcgatgc ctgcgaagcg aagaaaatta aaggcaccct cagggcagta
    20761 ttcagcaata aggccgacgc gttcggcctt gaacgcgcca gagaagccgg cattccggcg
    20821 caagcgctga ctgccgatcg gtttgacagc cgcgacgcct tcgatcgcga gttgattcgc
    20881 aagatagacg cgtatgcgcc cgatgtggtc gtgctggccg gttttatgcg tattctgagt
    20941 ccgatgtttg tcgcgcatta ctacgggcgt ctgctgaaca ttcacccttc cctgctgcca
    21001 aaatatccgg ggttgcatac ccatcgccag gcgctggaaa acggcgatga ggagcacggt
    21061 acctcggtgc atttcgtgac agacgaactc gacggcggcc cggtcattct ccaggcgaag
    21121 gtgccggttt ttgccaacga cagcgaagat gatatcaccg cacgcgtaca aactcaggaa
    21181 catgcgattt atccgctggt gattggctgg tttgcgcagg ggcgtctaaa gatgcgcgat
    21241 aacgccgcct ggctggacgg gcgtcgtctg ccgccgcaag gttatgcgtc tgacgaataa
    21301 tatgtcatcg gccagggctg cgtctgcttg ccggatggcg gcataaatgc ctatccggcc
    21361 tactcttttc ccttccttta tgctatcagt ttattgtcat atttttctga cgctgttgga
    21421 cattaacgcg taatgctcgc cataattatc aggcagtgtc ccgtgaataa aacggagtat
    21481 aggtagtaat gggtcaggaa aagctatata tcgagaaaga gctgagctgg ttagcattta
    21541 acgaacgcgt gttacaggaa gcagcggata aatccaaccc gttgattgag cggatgcggt
    21601 tcctgggaat ctattctaat aacctcgacg agttctacaa agtgcgtttc gctgaactga
    21661 aacgacgcat tattatcagc gaagaacagg gttcaaattc tcattcacgc catttgttag
    21721 gcaaaattca gtcccgcgtg ttgaaagcag accaggggtt cgacggcctg tacaacgaat
    21781 tactgctgga aatggcgcgt aatcaaatct ttctgatcaa cgagcgtcag ctctcggtga
    21841 accaacaaag ctggttgcgc cactatttta agcactattt gcgccagcat attaccccga
    21901 ttctcattaa ccgggagacg gatcttgttc agtttttaaa agatgattac acctatctgg
    21961 cggtggagat tatccgcggc gacaccatca actatgcgct gctggagata ccgtccgaca
    22021 aagtcccacg cttcgttaat ctgccgccgg agacaccgcg cagacgcaag ccgatgatcc
    22081 tactggataa tattctgcgc tactgcctgg atgacatttt taaagggttc ttcgactatg
    22141 acgcgctcaa tgcctattcg atgaaaatga cccgcgatgc cgaatatgac ctggtgcatg
    22201 agatggaatc cagtctgatg gagctgatgt cctccagcct gaagcagcgc ctgaccgctg
    22261 aacctgtgcg ctttgtctat caacgcgata tgcccgccgc gctggtcgac gtgctgcggg
    22321 aaaaactgac gatctcccgg tatgactcaa tcgtacccgg cgggcgctac cacaatttta
    22381 aagactttat taattttccg aatgtcggta aagccaacct ggtcaataaa ccgttaccgc
    22441 ggttacgcca tctttggttt gataaagaga agtttcgtaa cggtttcgac gcgattcgtg
    22501 aacgtgatgt gctgctctat tatccgtacc ataccttcga gcatgtactg gaactgctgc
    22561 gccaggcgtc gtttgaccca agcgtgctgg cgatcaaaat caatatttat cgcgtagcga
    22621 aagactcgcg cattattgac tcgatgatcc atgccgccca taacggcaaa aaagtcaccg
    22681 tggtggtgga gttgcaggcg cgcttcgatg aagaggcgaa tattcactgg gccaagcggt
    22741 taaccgaagc gggcgtccat gttattttct ctgcgcccgg gctgaaaatt cacgccaaac
    22801 tctttctcat ctcacgaaaa gagggcgatg acgtggtgcg ttatgcgcat atcggcaccg
    22861 gtaacttcaa cgaaaaaacg gcgcggctgt ataccgatta ttcgctgctg accgccgatg
    22921 cgcgcattac caatgaagtg cgccgggtct ttaattttat tgaaaacccc tatcgcccgg
    22981 tcactttcga ttatttgatg gtttctccac aaaactcacg gcgtctgctg tatgagatga
    23041 tcgatcgtga aattgccaat gcccagcaag gcttaccgtc agggattacc ttaaagctta
    23101 acaacctggt cgataaaggg ttggtcgaca ggctatacgc cgcgtcgggt tcgggcgtcc
    23161 aggtcaatct gctggtgcgc ggtatgtgtt ctcttattcc gcaactggaa ggcattagcg
    23221 ataatattcg cgcgattagc atcgtggatc gctatctgga acacgatcgg gtttatattt
    23281 tcgaaaacgg cggtgataag caagtttggc tctcttcagc tgactggatg acgcgtaata
    23341 ttgactaccg tatcgaagtc gctacgccta tcctcgaccc gcggcttaaa caacgcgtcc
    23401 tggatatcat tgacattctg tttagcgaca cggtaaaagc gcgttttatc gataaagaac
    23461 tcagcaaccg ctacgtaccg cgcggcaatc gccgcaaagt tcaggcgcag ctggcaattt
    23521 atgactacat caaatcactc gagcaaccag actaacgcta tgccaattta cgataaatcc
    23581 cctcgcccgc aggagttcgc tgcggtcgat ctcggctcaa acagctttca tatggtcatt
    23641 gcccgcgtgg ttgacggcgc aatgcagatt atcgggcgct taaaacagcg cgtccatctg
    23701 gcggacgggc tgggcgcaga taacaaactc agcgaagaag ccatggaacg ggggcttagc
    23761 tgtctgtcgc tgtttgctga acgcttacaa ggtttctccc cttccagcgt ttgtatcgta
    23821 ggcacccata cgttacgtca ggcgcaaaat gccgctgatt ttctcaaacg cgcggaaaag
    23881 gttattccct acccgataga gattatttcc ggtaacgaag aagcgcgcct gatttttatg
    23941 ggcgtagaac atacgcagcc ggaaaaaggc cgcaagctgg tgatcgatat cggcggcgga
    24001 tcaacagagc tggttattgg cgaaaacttc gaacccaggc tggttgaaag ccgtcgtatg
    24061 ggctgcgtga gcttcgcgca gctctacttt cccggcggcg ttatcaataa agaaaacttc
    24121 cagcgcgccc gaatggcggc agcgcaaaaa ctggaaacct taacctggca gtatcgtatt
    24181 cagggttgga acgtggcgat gggcgcttcc ggtacgatta aggccgctca tgaagttctc
    24241 ctggcgctgg gtgagaaaga tggcttcatt acgccggagc gcctcgataa actgaagtca
    24301 gaagtgttga agcaccgctc ctttaatgcg ctcagcctgc cgggtctgtc tgaagaacga
    24361 aaagcggtct ttgtgccggg cctggcgatt ctgtgcggcg tttttgatgc tctggctatc
    24421 cgcgagcttc gcctttccga cggcgcgttg cgcgaaggcg tgctgtatga aatggaaggc
    24481 cgcttccgcc atcaggatgt tcgcagccgt accgcaaaaa gtctggccaa tcaatacaac
    24541 attgacagag aacaggccag acgtgtgctg gaaaccacca tgcagatgta cgagcagtgg
    24601 caggcccagc agccaaaact ggcgcatccg cagcttgaag cgttgctccg ctgggcggca
    24661 atgctgcatg aggttggact gaatattaat cacagcggtt tacatcgcca ttcggcttat
    24721 attctgcaac acagcgattt gcccggcttt aatcaggagc agcaaatgat gatggcgacg
    24781 ctggtgcgtt atcatcgtaa agccataaaa ctggatgata tgccccgctt tacgctgttt
    24841 aagaaaaaac agtatctgcc gttaattcag ctacttcggc tgggcgtatt actgaacaac
    24901 cagcggcagg cgaccaccac accgccgacg ctgcggctaa cgaccgatga cagccactgg
    24961 acgttatgtt ttccgcatga ctggttcagc cagaatgcgc tggtactgct tgatctggaa
    25021 aaagaacagc agtactggga agcggtaact ggctggcgtc tcaatattga ggaagaaagc
    25081 tcgccggaga tcgccgcgta aattgtggat cagacgccgc gctgcggcgt ctgcctttac
    25141 tgaatctcag ataatagctg cggctcgcca attaaatatc cctgaagata gtcgatcccc
    25201 aacgacagca ctacgcttcg tatttcttcg ctctcgatat actccgcgac gacctgcata
    25261 tttttcattc gcgctaaatg acaaatagaa gccacaatct gataatcgag actgtttgac
    25321 actatattgc gaataaaact gccgtcaatt ttaagaatat cggcgtcaac gtttttcagc
    25381 cgcgcatagc tggcgtagcc agtaccgaaa tcatcaatcg ctatctgaca gccaaactgc
    25441 tgtagctgtc ccagtgtcaa ctgcgcctgc tcagcattgg tgagagagtt gctttccgtt
    25501 acctcaaaaa ccagttgcca gggttcaacc tgatattgcg taagcagctg cttaacttct
    25561 gcagggaaac gggcgcggca taccgatgtt ggcgacagat taatggcaaa acgatgcgcg
    25621 ggcatatatt cccggctggc cgccataaac cgtagcgtgt tttcaatcac ccagagatcg
    25681 atagcggaag acaaaccaaa ctcatgcgcc acgggtaaaa aattgtccgg gttgataacg
    25741 tcgccgttgt catccctgag tcgcagtaaa atttcatggt aaacgtcccc acgaacaccg
    25801 aaaataggct gcgccatcag gaaaaaatga tcgtgctcca acgcctgttg caggcgattc
    25861 atcatcgcaa ttctgccctt caaatcgcgc tgcaggtgca ttgcgccgcg ccgctgtaaa
    25921 tcctccggcg cgttagtcgt caacgaaaga tcggaactgg tgcttaattc gcccaacagc
    25981 agataaaggt ggctaaccgg agaacgcacg cagcagtagc tcacgccaac aggcggctgt
    26041 agcggcagtc catcccaaat aaaccgaaac tgcttaatat gtttatccag cgcttcaata
    26101 cgctgctgat gcgcctctgt attaagacgc agcaccaggt cgtgccctga catctggtag
    26161 acgcactcat ttgaggccaa catcggcgta atccagtgag agagcttttg cttatactgg
    26221 atgcgtagca tgacgccata atttttaccc aatagctcca gacccggcac gtgtaaaaaa
    26281 cagatcgtag accagggtgc atttttaagc gcgcggttta acgcacgtaa attgggaaga
    26341 tgtacaaccg ggtcaagata ggccagccgc cgtgcgcgac cactcactac gcgctgacgc
    26401 gtggccagta cagacatata attaacaata aaagaaaaaa ccagatagct cgaagaggta
    26461 atcgctaatt gcgtatcata acctgaatac cagggcatat aacgctgata ataatgaatc
    26521 gacgtaatta gcacgacggc ccagataatt gaaataaact tataaccata gcgcatcgcg
    26581 ccccacagca tgaccggcaa taataacgaa agcgtatagt tggtactaaa tattgagcta
    26641 ttatccgtca atggcataca cagtataaac attagtgtag tcaatacagc cagccaaata
    26701 acgatctctt ttttagtggc cttgctatca atctgtagct ttaattgctg ataatacccc
    26761 cgcaggtgca gcggattgcg gagagtacga ataataaaat agcacaatgg cacgccgaca
    26821 aggttaccga ccagtaacgc ctggtaatta atcagcgtgt tgatattaaa gggcattacc
    26881 cccatcaggc tggctttact ttcgtacatg ccaacaaaag cggcaaactg gtaaatgacc
    26941 agaaataatg tcgctgaaca aaatacctgc cagaacattc gttgaaacaa caggtgggcg
    27001 tcgccgtggg aaacattgtt tcgccggggg gaaaagacac gatagccgcc ccagcttagc
    27061 acgatagtaa tgataaagtg catcgtcaca gaaagggttt catacagccc tgtctgcggg
    27121 tatctgcgcc agaagatagc aagcacaatg cccggcagtg ctgcccagcc gaaaaagagc
    27181 atcagactaa gcataaaagc taacggcagg taaaaaagaa ccacatttcc agtgctggta
    27241 agcgcataag tatttgcgct acttaaaaca ggtagtaaaa tcgaagggag aatgagcggt
    27301 agtccccacc atttatctct gatatttata taagttttat tcagcttcat agatgctcag
    27361 cagaaccccc caatcccaaa ggggcgttaa cagacaggca tcccacctga ctttaaattg
    27421 atgatgcgat atacatcaca cgatagtcat cgattgtaat tattaaacaa aagtaacatt
    27481 tgatttaagt caattattac ctttctcctg cagcctttat tcgtcttttt attctttgtt
    27541 atcattaatt tattattaat gtaaatacta aaattatctt ccataacaat ataagataaa
    27601 tcaactgacg caattttaca ttaagaggaa ttgaccatcg gttcgcagta tgccttaatg
    27661 tagagtgaac gcaggcttgt tacgttcttc gccttgataa tacctttgaa gaacccagcc
    27721 tgatcccgcc cataccgctg ggccaacgtt aaggaaccct ttgtaagtca ggccaacagt
    27781 atgcgaaaac gacatcgatt taacactcgc atgacccgta tcgtactgct tatcagtttt
    27841 ctcttcttct ttggacgttt cgtctactct tctatcggcg cctggcagca ccatcaggat
    27901 aaaaaagaag cgcaacagtc atcgctttcg gtcaccacgc cgggacaacg ttaagctgtt
    27961 atccgttaaa atagtgatgg cggtattatc gtcacaggtt tgccgtgtta tccagcgctc
    28021 tgttatcccc ttccctggct tagcatgaac cgataaaaac aaagcatcgt atcatctaat
    28081 gctttgtttt ttagtctaaa aaaaacaatc aactacaaga aacgatagtt tacttttttt
    28141 aagattagtc ttaaatacat tcctttttgc gttattacct aaacaaggaa ttgtgatgaa
    28201 tttaaaaaaa aaatgctttg cctctggttt tgtttgcctc tttttctctt gccggatgcc
    28261 agtccaatgc ggatgactac gccgcagatg tttaccaaac cgggcagtta aacgcgaagc
    28321 aagaaacaaa gaccgtcaat attatctctg ttttgccagc gaaagttgcc gtagataaca
    28381 ccgccaataa aaaaaccgct cagaccttcg gcgcaattct tggggctgta gcgggcggcg
    28441 ttactggtca taacgtgggc tcaggtagcg gtttgggtac tactgccggc gcggttggcg
    28501 gcggagccgt tggcgcagcg gcggggtcat tggttaaaga taaaacgtta gttgaagccg
    28561 tatctttgac ttacaaagaa ggaacgaagg tttatacctc cacccaggtg ggaaaaacgt
    28621 gccaatttac caccggtctg gctatggtga tatcgaccaa agataacgaa acgcgaattc
    28681 aacccaatac gaaatgtcct gagaaaagct aactatcggg agattttatg aagaaagtta
    28741 ttttaggcgc tgttttattc actctaagcg gctcggtttt atcttcttct ttgcaggatc
    28801 agcttgcggc ggtagcccag gctgaacagc aaggaaaaaa tgaagaaaac agacagcgtg
    28861 atgctctgca agccaaacga gatcaagagg ctcaacagga aagacaaagg caagccaatg
    28921 cggcagcggt tgctaagcag cgagcaaaag cggcagaagc tgaacggaaa gcacggcaag
    28981 caaaattggc agcggaagcc gcgcaagata aagcgcgcga tcaaagctac gaagatgagc
    29041 ttcgtcgttt agaaattcag aaacaaaaac tggcgctggc cagggaagag gcccgggtaa
    29101 aaagagaaaa tgaattcatc gatcaagagc tgaaaagtaa agctgcccag acagatgtta
    29161 ttcaatctca tgctgatgca aacagaaatc tatctgaagg cggtcgcgat ctgctgcaaa
    29221 gcgaaggtaa agcccgtgag gaaaaggcaa gcggctggtt taactgattt cgctaatcat
    29281 ttatgtgtat tagctcagat ttgacctgac atagctatgg cacagaccta aacctaatct
    29341 gacaggcagg tctgtgccaa tagcggacgt tgttaacttt ggcccatatt catcaatgga
    29401 cgcaggtcaa tctatacgct aattgttttg cgcttaagtt ctgaactata gtgccgatag
    29461 taaaattaag tacttttgcc ttaaggaagc aaggtttgaa agatttttca aaatactcaa
    29521 aagcgttagg gatggctaag ttctatgttt atgcatttta tgacactgaa gatgcagcta
    29581 agaagccgtt ttatataggc aaaggcaagt cagaacgctg ccttgatcat ataaagtata
    29641 atgatgactc tccgaaatca gaacgaatta atcatctgtt aaaaacagga aatctgggta
    29701 tcgacatact acgccatggc atggatgagg caaccgcgaa gcttgttgaa gcaacatgta
    29761 ttgatctctt gggtgttgga gaactgacca acaaagtacg aggaagcagc tcccttatgg
    29821 ggcgaatcac gctggatgag ctcaatcatc ttcttcttaa gcaagagacg gaaatcgcac
    29881 ctgaacatgc cgggctcgct tttttgctaa acagcaccta caagtctggc atgagtgcac
    29941 ttgcattata tgaagctacg cgtggcgtct gggcaaaagt accaaaagat gaaaacctac
    30001 aatttgcata cgccacctac ggcggtttgg tgatggaagt ttacgagata cagtgctggt
    30061 tgaaggcagg ctctcagcaa tactttaccc gggaattggt catccccccc ccgaaaccaa
    30121 ccgttcagaa tttgttggac gaatcgcatc accagaaatc agaggattat acgttggcaa
    30181 gctaatcaaa aaatcgcgta gtcatggtag ccctttcgta aaagtcgggc tggcggagta
    30241 aactgacctg cttcccgttg attaatacac ctcaatgcca gtcatgttgt tgaagctacc
    30301 aatgtccgca cctcgctcga agccgactgt cagatttgat tgtgtgctgc cagtgaaacc
    30361 cactattgtg tcgatgcagt gctttgccgc cagaagctgt gcactacaca gaaaatgcat
    30421 ctatgcacat aaataaaaac cctctgcaaa aacagagggt taaattcact tttacctgtt
    30481 catgaaaaca caggaagggt tatcgactta ttcccactca atggtagccg gtggtttacc
    30541 gctgatgtca tacaccacac gggaaatccc gttgacttca ttgatgatgc ggttggaaac
    30601 acgacccagg aagtcatacg gcaggtgcgc ccagtgcgcg gtcataaagt cgatggtttc
    30661 gacagcacgc agagagacca cccaatcgta cttacgacca tcgcccatta cgccaacgga
    30721 gcgtactggc aggaagacgg tgaacgcctg gctgactttg tcgtacagat ccgccttacg
    30781 cagctcttca atgaagatgg catcagcacg gcgcagcagg tcgcagtact ctttcttcac
    30841 ttcacccagt acacgtacgc cgaggcccgg ccccgggaac ggatgacggt acagcatgtc
    30901 gtacggcagg cccagctcca gaccaatctt acgcacttcg tctttgaaca gctctttcag
    30961 cggttcaacc agccccatct tcatctcttt cggcaggccg ccaacattgt ggtgagattt
    31021 gatgacgtgc gctttaccgg ttgcagacgc cgcagattcg atgacgtcag ggtagatggt
    31081 gccctgcgcc agccatttca cgtcttccag tttcaacgct tcttcgtcga acacttccac
    31141 aaaaacacgg ccaatgatct tacgcttcgc ttccggatcg ttttcgccag ccaacgcgga
    31201 caggaagcga tcttctgccg gtacgtgaac gatgttcaga ccaaaatggt cgccaaacat
    31261 gtccatcacc tgctcggctt cgttgagacg cagcaggccg ttgtcgacga atacacaggt
    31321 cagattttta ccgatcgcgc ggtgcagcag cattgcggtt acggaagaat ccacgccgcc
    31381 ggagagaccg aggatcactt tatcgtcgcc tacctgctcg cgaatgcgcg ccacggcgtc
    31441 gtcgatgatc ttcgccggcg tccacagggc ttcacactgg cagatatcac gcacaaaacg
    31501 ctccagcatg cgcataccct ggcgggtgtg agtcacttcc gggtggaact gtacgccgta
    31561 gaagcgtttt tcttcgttag ccatgatggc gaacgggcag ctttcggtgc tggctacggt
    31621 cacgaagtcg gacggaatcg ccgtcacttt atcgccgtgg ctcatccaca cgtccagcag
    31681 cggtttgccg tcggcggtca gggaatcttc aataccgcga accagcgcgc tgtcggtcag
    31741 cacttcgacc tgcgcgtaac caaattcacg ctcattagaa ccttctacat gaccgccaag
    31801 ctgcatcgcc atggtctgca tcccgtagca gacgccaaat accggcacgc ctgcttcaaa
    31861 gacatactgc ggcgcgcgcg ggctgttttc ttcggtggtg ctttccgggc cgccggaaag
    31921 aataatgccg cttgggttga agtcacgaat ttgtgcttct gtcacatccc acgcccacag
    31981 ttcgcagtaa acacccagct cacgcacgcg gcgcgcaacc agttgagtgt actgagaacc
    32041 gaagtccaga atgaggatgc gatgcttatg aatgttttcc gtcattgacg cttattccga
    32101 ggcaagtgaa acagattaaa taaatcgccc gacgcgaagg tcgggcgaag aaaatcagga
    32161 gcccagacgg tagttcgggg actctttggt gatggtcacg tcgtgaacgt ggctttcctg
    32221 gatacccgca ccgctgatac gcacaaactc cgctttagta cgcagttcgt cgatggtagc
    32281 acaaccggtc agccccatac aggagcgcag gccgcccatc tgctggtgaa tgatctcttt
    32341 caggcgacct ttataggcta cgcggccttc gataccttcc ggcaccagtt tgtcggcggc
    32401 gttgtcgctc tggaagtaac ggtcagagga acctttggac atcgcgccca gcgagcccat
    32461 gccgcggtaa gatttgtaag aacggccctg gtagagttcg atttcgcccg gggattcttc
    32521 ggtacccgcc agcatagaac cgaccatgac agcgctcgcg cctgcggcga tggctttggc
    32581 gatgtcgccg gagaaacgga taccgccgtc agcgataacc ggaatcccgg tgccttccag
    32641 cgcttcaact gcgtcagaaa cagcggtaat ctgcggaacg cccacgccag tcacgatacg
    32701 agtggtacag atggaacccg ggccgatacc gactttcacc gcgctgcaac cggcttccgc
    32761 cagtgcgcga gcgcctgcgc ccgtcgcgac gttgccgccg atgatttgca ggtcaggata
    32821 tttagcacgg gtttcacgga tacgttgcaa cacgccttca gagtgaccgt gagaagagtc
    32881 gatcagcagg acgtcaacgc ctgccgccac cagcgcgtca acgcgctctt cgttgcccgc
    32941 gcctgcgccg accgccgcgc cgacacgtaa acggccctgc tcatctttac aggagtttgg
    33001 tttacgttcc gctttctgga aatcttttac ggtaatcatg ccaagcagat ggaagttatc
    33061 atcaacgacc agcgcttttt ctacgcgttt ttcgtgcatt tttgccagca cgacttcacg
    33121 ggcttcgcct tcacgaacgg tcaccagacg ctctttcggc gtcatgtaaa cactcaccgg
    33181 ctggttcagg tcagtcacaa aacgcacgtc acgaccggtg atgataccca ccagctcgtt
    33241 atcttcagtc accaccggat agcccgcaaa accgttacgc tcggtcaggg ctttcacttc
    33301 atgcaacgtg gtggttggca ggacggtctg cgggtcggtc actacgccgg actcgtgttt
    33361 cttcacgcgg cgaacttctt ccgcctggcg ctcaatagac atgtttttgt ggataaaacc
    33421 gatgccgcct tcctgggcca gggcaattgc caggcgcgct tccgtcacgg tgtccatcgc
    33481 cgcagaaagc ataggaatat tcagacgaat agttttcgtc aactgcgtgc tgagatcagc
    33541 agtattcggc aaaacggtgg agtgagcggg aacaaggagg acgtcgtcaa acgtcagggc
    33601 ttctttagcg atacgtagca tgggcaatat ctcacctggg aggttaataa atattgccgc
    33661 ggcattatac agaacgtaat cggttgcatc tacatttttt tgcaaatagt gcttgcgatc
    33721 ccccgtgagc aggttactat cgattgaata acctgctgat ttagaatttg atcccgctca
    33781 catgttatcc tctcaaactt cctcaatttt taccgtaagc cgccttaacc agacggttcg
    33841 tctgctgtta gaacaggaga tgggacaggt atggatcagc ggcgagattt ctaatttcac
    33901 gcagcctgcg tcgggccact ggtactttac gctcaaagac gataccgctc aggtgcgctg
    33961 tgcgatgttc cgcaacagca accgccgggt gacgttccgc ccgcagcacg ggcagcaggt
    34021 gctggtacgc gccaacatta cgctgtacga gccgcgcggc gattatcaaa tcatcgccga
    34081 aagtatgcag ccggctggcg aaggcttgtt gcagcagaag tatgagcagc taaaagccaa
    34141 actccatgcc gaaggcttgt tcgatcagca gcataaacag ccgttgccct ccccggccca
    34201 ctgcgttggg gtgatcacct cgaaaaccgg cgcggcgctg cacgatatcc tccacgtgtt
    34261 gaagcgtcgt gacccatccc tgcccgttat tatctatcca accgcggtac agggcgacga
    34321 tgcgccgggg cagatcgttc gtgctatcga actggcaaac acgcgcggcg agtgcgacgt
    34381 gctgatcgtc ggacgcggcg gcggttcgct ggaagatttg tggagtttta acgacgaacg
    34441 cgtggcgcgg gctatttttg ccagccgtat tccggtggtc agcgccgtcg gtcacgaaac
    34501 cgacgtcact atcgccgatt ttgtcgccga cctgcgcgcg ccgacgccat cagcagcggc
    34561 agaaattgtc agccgtaacc agcaggagtt gttgcgtcag atccagtccg cccagcagcg
    34621 tctgggcatg gcgatggact actacctcgc caaccgcagc cgtcgtttca cgcagatttt
    34681 tcaccgtctg caacaacaac atccgcaact acgtctggcc cgtcagcaaa ccgcgctgga
    34741 acgtctacgc caacggatgg gatttgcgct tgaggccagg attaagcagg ccactcagcg
    34801 tcagcaacgc gtaagtcaac gcctgagcca gcaaaatccg cagccgcgca ttcaccgcgt
    34861 gcagtcgcgc atccaacagc tggaatatcg tctgacggag aatatccgct cacggttaag
    34921 cgaacagcgc gagcgttttg gcaacgcggt cacgcatctg gaagcggtca gcccgttagc
    34981 cacgctggcg cgcggctata cggtttcgac gacaacggac ggcaaggtgt tgaaaaagat
    35041 caaacaggtc aaagcaggcg atatcatgac cacgcggctg gaggacggct ggcttgaaag
    35101 tgaagtcaaa tccgtcacgc cgggaacgta atccaacact cccccacctt ttgcagcgcg
    35161 atgttgggtt tcgacttcac ctcagccaac ccacgcgcca cgtcggataa ggtgtagcca
    35221 caatccgacg ctcaaccggt ttgtcattcg cctcaaaacc gggcagggaa tacccgcccg
    35281 gttttgtcta acttaccagt tatagcgcag attgaggcta ccgttcagat cgccaaagtc
    35341 attgctgcca gtctgcccgg caacctgagc gcgaacgctc cactgcttat cgatatctgc
    35401 ctgcagaccc actttcagct ccgcacggtt agccggaaga tcctgtttca ccgtggcatc
    35461 atcaaacgat accgacacat catcgctggt gtgcagccag ttggcttcag caaacggctg
    35521 gataaccgta cggctgcctt tgtacagctt gccgtcaaca cgcagaccca ggcgcgttgt
    35581 ccaactgtcg ccatcctgac cgtcgatccg ggtgccgtag ttatccttca cgctatccgc
    35641 tgagtagttc tgccagacaa cctgcgcctg cggcgtcaga ctgacagtat taccgttgct
    35701 aagcgcaata tcgtagcgat aaccggtttc cagcgagaca gcattagcgg ttgaatcata
    35761 agattcagat cccgcatcac cgctctctac gctgttgttg tagaaaccat attggtacca
    35821 gctgtcgaca tacgcgccgc tatgcgtttg ggcatcggca aaccaggtgg catagacgcc
    35881 aaggttgtag ccgtctacgt tggcgctgct ggtgaactgg ctaccgtctg cgccacggtt
    35941 accggtgctg tcggtatcgg cgttgatgta gctcgctatg acgccaacgg taatgctctg
    36001 ttggccgtta ccccaagcca gaatgtcgcc gcctagctgg aactgagagt agttgctgtc
    36061 catatcgata ttaccgctga cagcctctga ttccgcttta cccgctttga agcgtgccca
    36121 gacgctgcca tcagcgttac gatactggct gccctcgcgg tcatagaggg tctgtctgca
    36181 tttgcaggtt gcgcgccatc cactggttgc ccatgtacgc gccgatatcc gcacggtact
    36241 gtggtgcgac atcgccgccg tcgtccggag gcgtgacatc gccaccgtcg ccgccgtcgt
    36301 ccgaaggcgt gacatcgcca ccgctgtcgt catcatcaga ctgtgctttt gacgccagat
    36361 accagtcgtt gtcactttca ttccagtaca gacggtaggt atacagactg gcgtttacct
    36421 cattttttaa cacaaacgca tcgctggtcg atacgccgcc aacatccacc acttcgatac
    36481 cgttagtggt ctgcgcccca tcgccgatgc cgttgatgta cagatcggtg gtgccggagg
    36541 catcgccggt aatgaccaac ttatcggtcg ccgaatcatc gtcgcccagg acggtattca
    36601 ggtaaagcga gccgccgttg ccggttttat cgcccagtac gctggtgact tcaaagctat
    36661 cgcctgcgcc cagagtgaag gtgccgtgtg ctggcgtcgc tgacgtggcg gtcgcattcc
    36721 agctcagccc ttcggtaagc aggtattcag actggtcttg aggattgatt gttccggtta
    36781 cggtcagata gtccggcttg tcggtgaggt tcatcgtcag gctggtaaag tcgccgctga
    36841 tatcgctgtc catatccatc agtttaaagg actggaactc cgcgtcggag gcgcgcgctt
    36901 gtaggctggc gtcgctgacg accaaatcac cgccaagcgt ggcgctgcca ccggtaatca
    36961 gcggttgcgc tgagtcacta ttcagctcaa cgttcagcgt actgccatct tcctgaatta
    37021 acgcgctgtc gccgagatcc aacgaggtgc cgagcgccag ttgggtcgtc gcgccgccat
    37081 gagtggtgat gccgcccacc gcgctgactt caccgtctgc gtccagtacc agcgtggcgt
    37141 tattgtccac cagaccggtg cccagcgccg tcgtgctggc ggcgaccagc gtaccttcat
    37201 tgattgtagt gccgccgctg tagtcgttgt cgccggagag gatcagcgtg cctgcgcctt
    37261 ctttggtcag cgacttaccg tcccatgtgc tgcccggatc cagcgcgtca tcaacatctg
    37321 tcagtttagc cgcaacgtta aagttgccgt cagggtcact tagcgtaaag gtgccgtggg
    37381 cgtcggtaga agcgttgtct ctgtccgcat accaggagag ggaggccgtc agatcatagt
    37441 ttgtgctatc tgcttcgtcg acttttccgt cgatggtcag gaagtcaaca tcttcgctat
    37501 tcattcccgc gacggtcaaa tcattgaaat cggtcgtaat ggcgctgtcg ctgtcaatca
    37561 gcgtgtaggt gtatgcctca ggcgtccagc tgtctgtgac gttgccgatc ccggtaatgt
    37621 tgagcgcacc agccaacgag acgctgtcag cggtaatggc gctttcacca ttagtcttac
    37681 tgaggtcaat attcagcgta ctatcggctt gctgagtcag cgagtcgacg ttgagcgtcg
    37741 tacctttgga cagctcagtc gttgctccag actgggtcgt gacattcgca aggttgaatt
    37801 cgccctccgc gtccagcttc agcgtactcg cgttatcgac atcaccgccg cccagcgcgt
    37861 taacgttggc ggcaatcagc gtaccgccgg aaatagtggt gccgccggag taagtgttgt
    37921 cgccgcttaa cgtcagctcg cccgtaccgg ttttcatcag cgaaccgttg ccggaaagcg
    37981 tattttccag ctcgccttcg ccgacctgaa gcacgccgct gttggcaaca gccccggtac
    38041 ccagcgaatc tgcatggtca gcaatcagcg tgccgtcgga aatagtggta ccgccgctgt
    38101 agttgttatc gccggtcacg atcagctcat cgctaccgct tttgacaatt tggccctcgc
    38161 cggtcacgtt gttatccagc gtgccttggc tcaactcaag ctttgcgttt tctgcaatgg
    38221 ccacgtcgcc gctgccgagc gcggcggcat cattcgcaga cagcgtaccg ccgttaatgt
    38281 cggtattgcc gaagtcgttc gccgtgttgc tgaggacgag cgtaccgtcg ccttctttga
    38341 acagcgtttt accgtcccag ttggaggtgg ccgcggtttc atccagttcg ctggtgacgg
    38401 taaaggtatc gcctgcgtca acggtaaagg tgccgtgcgc aacgcgcgca gattttgcgt
    38461 ccgcgtacca gctcaggccc gtagacaaca cgtagttggt attatcattc gcatcaacgc
    38521 ccgcgttgat cgtcaggtaa tccggcatag cagaggtgtc ggcatccagc gttacgctgt
    38581 caaaatcggt agtaatcgcg gtttgcgaat caattagcgt gaacgatcct aactgctcgt
    38641 cggtttcggg cgcgacaaag gtggccgctg agctaaggtt cagtgtccca tccagcgtca
    38701 cgttggcggc tttgataatt ggcgagctgt tggcggtatc cagcgtcgcg tttatctggc
    38761 tgccgtcctg caaggtcagg gtattgccca ccgtcagcag cgtgcctgtc gaaccgctct
    38821 cgttgttcag cgtaatgtcg ccgttgttgg tcaggttgcc gatgattgac gagtcggtca
    38881 tattccactg gctagtatcg tcgagcgaca gtgtagtaaa catcgcatct acactaccgg
    38941 ttaacgtgga accctggctt aaagacagcg atgacgatga catgtcactc tgaacaacgt
    39001 caccgttcaa tgtcgtattg tcggcctgaa tgaccgcctt gctgcccagc ttgatcactg
    39061 ccggcgcgtc aaatgcgcta tcggttagca cgataggatc gttaatcgtc gtgccagagt
    39121 ccacatgcag cgcaatcgtc tctgaattaa cctgtgcttt gttaaccgtc agcgcgttga
    39181 tatcatcata cccaccgctt ttacctttgc ttgttataaa gatgccgtcg ccgtcggcgt
    39241 tgatggtggc gccgttaata tccacgctgg aggcgaggat tttaataccg atgcctttgg
    39301 agttgatggc catcgaatct ttatcatcag agatgctcac cgttgaggcg tttttcacct
    39361 caatagcggc gcctgtggca ttatcgtgcg tgacggtaga gttcgtaata tcaagaacgc
    39421 ccttgttgga cacaagaagc gtactatccg tacccgtgga gctcatcgtg ctatcggaca
    39481 cattcagcca ggagttgtat gtcgtctcgc ctactacgcg cacctggccg tttgtcagcg
    39541 taattacgct cccgtcctta atgttaagcg tgctacctga ttgtgacact atgctgctac
    39601 ggctttgcgt cgttgccgta acgtcggtgc caatcagggc agcccatgac tcgccagaga
    39661 gggtcaggat gccgtaatta cttccgatct ggatgctccc gccattcagc gtcatgctgc
    39721 tttgcgcctg gaggtcgata cctgccgtgt aggttccttc cgtagagatc tgcgccccgg
    39781 tcaggtcaag tgttgcgccc ttgttgaggg taactgccgt ggcgatagca tgagttccct
    39841 gaacaggatc gccgccgccg ttggtgttaa tcacgacatt tgtacctgta cccgacgttg
    39901 cctgccagcc cccttcgggc gttgcaaggc cttcgaggtg cagtgcagaa ccttcaccag
    39961 tgcctgagta ggaaatcggc gaatcgtcgc tcaggtcgtg cttgacccca tcggtgtatg
    40021 acaccggatt atcggcgatg gccagcgggc tggcaaagcc aagcgcggca acaattgcca
    40081 gggccagcgc atggtgtctt gcccatcctg aatcaggctt tttaatagaa ggggcgactt
    40141 cattagcgtg cgcctgtatt ttaactttgc tgtggcttcg cgccagttct gaagctacga
    40201 catacatatt tcgcacggcg ctccagacga tactgtaggt cctgttcaat ttttaaattt
    40261 ccttttaata acattcacga agcaaacttg atttgattgg ctgcaaatag cttttaaatg
    40321 gtgtatataa atgagttaaa taataaataa caaaaatatg attctatgaa tggttgctgt
    40381 catctgtaac aatgtattat caaagacaaa ttattaacta atttcaagcc ttatttcaat
    40441 accaggtcag cttctggtta atttataatt aatatgaata tatttatcta tttaa
//
LOCUS       DAJVKX010000030        40204 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000030 DAJVKX010000000
VERSION     DAJVKX010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 40204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40204
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.030"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            77..475
                     /locus_tag="OPY25_001548"
     CDS             77..475
                     /locus_tag="OPY25_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HCS0927190.1"
                     /translation="MKKSDGEIHEKTASWGILQSEWLRKCGRLLLLLLYRFVIGWAFF
                     QLLAMIVAGIFLLGVLLFHPIIFVQTIAITEKLNHASLDLWHILKLCLWHYGIIAGFI
                     FMAECTLSKSIRQVQRLSKKFGAQDFSSRP"
     gene            508..738
                     /locus_tag="OPY25_001549"
     CDS             508..738
                     /locus_tag="OPY25_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927191.1"
                     /translation="MAMTSRPNYLGSRGILCVCTTAVNRNFSALSPTIDVFLTNCLPD
                     YIVVLSLAKQCYLVMEGDNNCTIDYQISFLVR"
     gene            1001..1771
                     /locus_tag="OPY25_001550"
     CDS             1001..1771
                     /locus_tag="OPY25_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCS0927192.1"
                     /translation="MVKCVSSFLLFSLLSVQAISAENHIDLHQPKDFVDITTVAPDVQ
                     VDMRYFTSHNFIGRPIKGYNAPVCLLTRPAANAVKQVADRLRPFGLTLKIYDCYRPQS
                     AVNDFIAWAKDPSQNQMKNEFYPQVEKNRLFEEGYLAARSGHSRGSTLDLTIVPLDSK
                     IPIYHPGRPLVNCTASAAQRSPDNSLDFGTGFDCFSPLSHPDNVMLTAQQRANRLLLQ
                     TLMRDAGFTPLDTEWWHFSLTHEPYPNTWFDFPVKQRP"
     gene            1907..3331
                     /locus_tag="OPY25_001551"
     CDS             1907..3331
                     /locus_tag="OPY25_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCS0927193.1"
                     /translation="MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVG
                     HAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAHVIRDEAVDINTYIFEMLQASRD
                     TSVVPFASAFPDPRLFPLPQLNRSLAQVSKTETAMSVIENLPPGNAELRYAIARRYAQ
                     QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSI
                     PTDVKEGIDLMALEQALQEYPVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVTL
                     IEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRIGWVAGGSHARQIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKI
                     HHNDSGYFLWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWG
                     EREEQAVKQLGSLIREMLSAKSLV"
     gene            3446..4891
                     /gene="patD"
                     /locus_tag="OPY25_001552"
     CDS             3446..4891
                     /gene="patD"
                     /locus_tag="OPY25_001552"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460556.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HCS0927194.1"
                     /translation="MTIWENAMQYQLLINGVLVDGEGERQSVYNPATGEVILEIAEAS
                     PVQVDAAVLAADSAFAEWGQTTPKARAECLLKLADSIEQNALEFARLESQNCGKPLHC
                     VINDEIPAIVDVFRFFAGAARCLSGLAAGEYLEGHTSMIRRDPIGVVASIAPWNYPLM
                     MAAWKLAPALAAGNCVVIKPSEITPLTALKLAALAKDIFPPGVLNVLFGRGQTVGDVL
                     TGHEKVRMVSLTGSIATGEHILRHTAPAIKRTHMELGGKAPVIVFDDADLDAVAQGVR
                     TFGFYNAGQDCTAACRIYAQRGIYDALVEKLGNAVSSLKMGAPEDKSTELGPLSSLAH
                     LKRVTAAVEEAKALSHIRVITGGSQTEGKGYYFAPTLLADAKQEDAIVQREVFGPVVS
                     ITVFDDEDQVLRWANDSRYGLASSVWTQDVGRAHRLSARLQYGCTWINTHFMLVSEMP
                     HGGQKQSGYGKDMSLYGLEDYTLVRHIMVKH"
     gene            complement(4996..5091)
                     /gene="yncL"
                     /locus_tag="OPY25_001553"
     CDS             complement(4996..5091)
                     /gene="yncL"
                     /locus_tag="OPY25_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HCS0927195.1"
                     /translation="MNVSSKTVVLINVFAAAGLLGLISLRFGWFA"
     gene            5229..5327
                     /locus_tag="OPY25_001554"
     CDS             5229..5327
                     /locus_tag="OPY25_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GhoT/OrtT family toxin"
                     /protein_id="HCS0927196.1"
                     /translation="MSNKKSILRAFFPLVGATWPISFPVALLFSLF"
     gene            complement(5372..7519)
                     /locus_tag="OPY25_001555"
     CDS             complement(5372..7519)
                     /locus_tag="OPY25_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence effector SrfC"
                     /protein_id="HCS0927197.1"
                     /translation="MTKPLNATQAVIEWVNNTRRYATRLDDEADALLAQLTLAAADES
                     ALNAACASSHGCVGLYGYAQSAKAHLLTTLCGNENGKLEIITPDRDYDYFSHINPGHA
                     PANMAIRFTRDIFSNESGWPLRLRLISEAELVQIFIAWTSSSPVCRQVEKSIITSRLE
                     KWQSLRQPQPVPGVTAEEVATIASFWRSCLPSARQHIDDATWQHFASLLPALDLTTRA
                     HAWALLWGEQPEITQQWLALAHMLQQTGHAGELAAPLSLLVDHFGLPAENFLTQMALT
                     ASDTQSDVVVHPVKEGRLLNAVSLSLDSLALLTRELVLTVENSVLDNVDLLDIPVAPD
                     SHPHPLWRAKLGWMLAHYRQQIQPDVLVICNALASRSQTSTAARHLLEWVNATQPQHE
                     SALPGVVWAITPQDARFATQQNLDEAVQQLMGKPGVHWGTLQALDKHSMQRLVEWLSQ
                     ATSAPQRQARLQALREQLRGRVRDLLPMCDDARLPVETVIRRLQAQAARHGDLLAGLL
                     PPVQNFEALLRTRQSREEQVSGLFNDAIDLFADEPTHALASEGHETGYQAHKMWINHL
                     RQWAHCRDNAQRLGLEPQMLNAVAEILITASYRLGLPQQLQKTMQREEVSGAQLHAII
                     GNFIAWLGYANIEEAQRPASRVQKGAAIFAATPRSTMLRLTKLDEQPVHAASRYVYDW
                     LVALYTLANENAGYRHPQDVTDVDRAQLIALIA"
     gene            complement(7516..10497)
                     /locus_tag="OPY25_001556"
     CDS             complement(7516..10497)
                     /locus_tag="OPY25_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor SrfB"
                     /protein_id="HCS0927198.1"
                     /translation="MLVNLCDYKQSVTLIANSGVQFLDFGLTPQESAHYGRFVRKTAN
                     GPLLRLDFDLTSGRYTLPGRAGGQPEVVKPESTQTLHYSLDVLDGIWLPLPFLRFNPP
                     RTFIDGPDNWARIQVRKLSEPDSAGNTHRITLAFDSQLAKNMPAALAPCENDLLNGTR
                     FALAWRDEEVADFLDQTWIDGWLRESFLQYASQVENRPEQAIQQALRSFEYQAHWLNL
                     LTLLGEQLTVPEVKFVTHTLSTPAIPVDLILDVGNTHTCGVLIEDHGDANDGLRQTAE
                     LQVRSLSEPQYLNDPLFTSRVEFSEARFGKQHFSVESGRDDAFVWPSIVRVGDEARAL
                     AMQRVGTEGSSGISSPRRYLWDETPALQDWRFSQIHGKTQREPLATAFPLMNLMNDDG
                     QPLFRLPHEERLPVFSPQYSRSTLMTHMLCEILAQALGQINSVATRLRLGFPASPRQL
                     RTLILTLPSAMPKQEREIFRQRMFEALALVWKAMGWHPQDEDFTTPKQREKSVVPVPE
                     IQMEWDEASCGQLVWLYNEAISHYAGRTESFFNALARPDRQPEPGVVPGRALRVASID
                     IGGGTTDMAIVHYQLDDGVGANVKITPHLLFREGFKVAGDDLLLDIIQRCVLPSLQTA
                     LQRAGVTDAAALLATLFGDSGRIDTQAILRQQTALQLFMPLGHAVLSAWEQSDINDPF
                     AGLHATFGDLLIRRPTSNVMNYIQQAIDHALPSGSPTFDIFNVPLQIQFSQLQEALLA
                     GQFTLTTPLHAVCEAISHYHCDILLVTGRPTCLPGVQALIRHLQPVPVNRIVWMDKYQ
                     VHEWYPFSQQGRIGNPKSTAAVGAMLCSLALDLRLPRFNFKAADIGAYSTVRYLGVLD
                     NTVNTLRDENIWYHEIDLDKPGATLDARLHFPLRGNVTLGFRQLANSRWPATPLYCLS
                     INSAELAKTIAGDGVLNVRLKLRGSSKDSAPESFILSDAWLQDGTPVAADALTLKLNT
                     LADRRHSGSHYWIDSGSVYLK"
     gene            complement(10502..11827)
                     /locus_tag="OPY25_001557"
     CDS             complement(10502..11827)
                     /locus_tag="OPY25_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ssrAB-activated protein"
                     /protein_id="HCS0927199.1"
                     /translation="MAKSLLRSGNLDDYQAVGGGGQAVFESALQIRETLRLRKQQTMV
                     DCLAIPQLNDNGDRVDWYSPIEGQAIAWKAADEETRSRALRYLASTFESAAALSRKSL
                     QSGKTALQLFGSLLEKATQFPGENHVFLVNGKPVITFWGFVNLNENTRDDVLDCLRVT
                     EAISDIPLVEPEPQPEEKPLVEAAFSQADEPLLTSVIEPPKMPEEPAAPPVIVSEPKP
                     AAPIPVAEAKRARRLPLWSLPVAAVVIAAVATPFFWPSSSVDGASPVRTAPVATAKTD
                     VTPMPELTAHLPLHRAEVTSAPKAAPLPEAPVIIAAIPKDALVMDNTQMKLGTTRFLN
                     GSWRVSVDVKDPITGKPPSLRYQIQNNKGIARVVHGDNVVCRAEIFSGLHQTGELMIK
                     SRGNARCTDGSRYPMPEITCKAGVNDVATCTARYGDHAAIPLTFKKIGA"
     gene            12051..12284
                     /locus_tag="OPY25_001558"
     CDS             12051..12284
                     /locus_tag="OPY25_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2526 family protein"
                     /protein_id="HCS0927200.1"
                     /translation="MSHLEEVSARVDAAIAESVIAHMNELLIALSDDAELRHEDRYVQ
                     QQRLRTAIAHHGRQYQEDRDARREQLTKGGTIL"
     gene            complement(12289..12738)
                     /locus_tag="OPY25_001559"
     CDS             complement(12289..12738)
                     /locus_tag="OPY25_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0927201.1"
                     /translation="MNQSLTLIFLIAAGVGLVVQNSIMVRITQTSSTILIAMLLNSLV
                     GIVLFVTILWFKQGATGFGELVASVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLALDIARSHGVTLRAMVGPAFGALLLVIGAWLIAKRQF"
     gene            complement(12738..13253)
                     /gene="mddA"
                     /locus_tag="OPY25_001560"
     CDS             complement(12738..13253)
                     /gene="mddA"
                     /locus_tag="OPY25_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HCS0927202.1"
                     /translation="MTIRFADKADCAAITEIYNRAVLHTAAIWNDRTVDTDNRLAWYE
                     ARQLLGYPVLVSEENGVVTGYASFGDWRSFDGFRYTVEHSVYVHPAHQGKGLGRKLLS
                     RLIDEARRCGKHVMVAGIESQNAASIRLHHSLGFTVTAQMPQVGVKFGRWLDLTFMQL
                     QLDEHAAPDAC"
     gene            13465..14502
                     /locus_tag="OPY25_001561"
     CDS             13465..14502
                     /locus_tag="OPY25_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCS0927203.1"
                     /translation="MKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLR
                     TVFLSLDPYMRGRMSDEPSYAPPVEPGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGW
                     QDYDISDGEGLVKLGDNPQHPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQG
                     IDIYYENVGGKVFDAVLPLLNTSARIPLCGLVSGYNATTLPDGPDRLPLLMATLLKKR
                     IRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIHYREQITDGLENAPEAFIGLLAGKNF
                     GKVVIRLADDA"
     gene            14836..15501
                     /gene="mcbR"
                     /locus_tag="OPY25_001562"
     CDS             14836..15501
                     /gene="mcbR"
                     /locus_tag="OPY25_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid/biofilm transcriptional regulator
                     McbR"
                     /protein_id="HCS0927204.1"
                     /translation="MPGTEKTQHISLTTQVENRLKHQLSIGALKPGARLITKNIAQEL
                     GVSITPVREALLRLVSSSALAVAPAQAFMVPEISLESLLEINTIRTALEEMAVVAAAG
                     KITPDREQTLNALLDEFQQALESGVMEKILLANRAFRFEIYHYADMPTLYAMIEQLWV
                     RLGPSLHFLYDNFKLDDYQNGVNLYRKLLNALVTGDKEASRHCLQNVLQQNVATIKNQ
                     YFM"
     gene            complement(15557..17677)
                     /locus_tag="OPY25_001563"
     CDS             complement(15557..17677)
                     /locus_tag="OPY25_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HCS0927205.1"
                     /translation="MKIISVRQRLYPALLLPLTFSPVLQAASAPNEQTMIVTATPQTV
                     SELDTPAAVSVIEGEDMRLATPRVNLSESLTSVPGLQVQNRQNYAQDLQISIRGFGSR
                     SAFGVRGIRLYVDGIPATMPDGQGQISNIDINSIQNVEVLRGPFSALYGNASGGVINV
                     TTETGRQPPTLEASSYYGSYGSWRYGLKATGAMGDGTQPGDVDYTVSTTRFTTRGYRD
                     HSGARKNLANAKLGVRLDDVSKLSLIFNSVDIKADDPGGLTESEWKADPQQAPRAEQY
                     NTRKTIKQTQAGLRYERQLSAQDDISVMAYAGERETTQYQSIPLVAQLKPAQAGGVIT
                     LQRHYQGIDSRWTHRGELGVPVTFTGGLNYENMSENRKGYNNFRLNNGTPEFGHKGDL
                     RRDERNLMWNVDPYLQTQWQLTQKLSLDAGVRYSSVWFDSNDHYIAPGNGDDSGDASY
                     HHWLPAGSLKYALTDAWNLYLAAGRGFETPTINELSYRADGQSGFNFDLKPSTNDTVE
                     VGSKTRIGNGLLTAALFQTDTDDEIVVASSMGGRTTYKNAGKTRRQGAELALDQRFAG
                     DWRVKASWTWLDATYRSNVCQGQNCDGNRMPGIARNMGFASLGFIPDEGWYAGTDVRY
                     MGDIMANDENTAKAPSYTVVGLNTGYKFNYSQLTVDIFGRVDNLFDEEYIGSVIVNES
                     NGRYYEPAPGRNYGVGINLAWQFE"
     gene            17941..19002
                     /locus_tag="OPY25_001564"
     CDS             17941..19002
                     /locus_tag="OPY25_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HCS0927206.1"
                     /translation="MHLRHLFSPRLRGSLLLGSLLVASSFSTLAAEDMLRKAVGKGAY
                     EMAWSQQENALWLATSQSRKLDKGGVVYRLDPVTLEITQAIHNDLKPFGATINAATQT
                     LWFGNTINSAVTAIDAKTGDVKGRLVLDARKRTEEVRPLQPRELVADAATNTIYISGV
                     GKESAIWVVDGETIKLKTTIENTGKMSTGLALDSKAQRLYTTNADGEFITIDTASNKI
                     LSRKKLLDDGKEHFFINLSLDTAGHRAFITDSKATEVLVVDTRNGNILAKIAAPASLA
                     VLYNPTRNEAYVTHRQAGQVSVIDAKTYNVVKTFDTPTYPNSLALSADGKTLYVSVKQ
                     KSTREQEATQPDDVIRIAL"
     gene            19147..19368
                     /locus_tag="OPY25_001565"
     CDS             19147..19368
                     /locus_tag="OPY25_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCS0927207.1"
                     /translation="MKKLFICSGLGMMFFMLAGCTTNYVMTTKNGQTIVTQGKPQLDK
                     ETGMTSYTDQEGNQREINSNDVAQLIKAD"
     gene            complement(19445..20938)
                     /gene="ansP"
                     /locus_tag="OPY25_001566"
     CDS             complement(19445..20938)
                     /gene="ansP"
                     /locus_tag="OPY25_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HCS0927208.1"
                     /translation="MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGIFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIELVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     LLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMS
                     MGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIMVCQMRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IASLPLIAILLVAGWFGVRRRVAEIHRTAPVTADSTESVVLKEEAAT"
     gene            21451..22083
                     /locus_tag="OPY25_001567"
     CDS             21451..22083
                     /locus_tag="OPY25_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector protein steA"
                     /protein_id="HCS0927209.1"
                     /translation="MPYTSVSTYARALSGNKLPHVAAGDYENKLSTKIMKGILYVLTA
                     GLAYGFTRVIEHYCNVTPKVDEFCANAGNIHNHLADAVRDEQFIIDVELSDGRMLTFE
                     QLSLMAGREPIVRISDGEHSVEVKGSFEDICMRLEEGFFEAPAYYGYDIDEKYKTVRE
                     RIAAYNALPQALGAIPSLKYYTDRANDMPEAKAQRAADIKDRYHNYLDKY"
     gene            22366..23211
                     /gene="nhoA"
                     /locus_tag="OPY25_001568"
     CDS             22366..23211
                     /gene="nhoA"
                     /locus_tag="OPY25_001568"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HCS0927210.1"
                     /translation="MTSFLHAYFTRLNCQPLGGPTVEALRTLHLAHNCAIPFENLDVL
                     LPREIQLDETALEEKLLYARRGGYCFELNGLFERALRDIGFNVRSLLGRVILSHPASL
                     PPRTHRLLLVDVEDEQWIADVGFGGQTLTAPLRLQAEIAQQTPHGEYRLIQEGSTWIL
                     QFRHHEHWQSMYCFDLGVQQQSDHVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTRYHQGHAVEQVNIPDVPSLYQLLQQQFGLGVNDVKHGFTEAELAAVMAAFDTH
                     PEAGK"
     gene            complement(23247..24140)
                     /locus_tag="OPY25_001569"
     CDS             complement(23247..24140)
                     /locus_tag="OPY25_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HCS0927211.1"
                     /translation="MKPQIYHVDAFTSEPFRGNSAGVVLHADTLSDAQMQLIARELRH
                     SETAFLLKSEESDVRIRYFTPTVEVPICGHATVAAHYVRATVLGLGNTTVWQTSLAGR
                     HRVEIHAEHNDYRITLEQGQPSFEPPLVGEIRAAIITALNLTEDDIVPGAPIQVASTG
                     HAKVMILLKPDVDIDALSPNLAALTAISQQIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHGLMAHDGKTLQIQGHQGRALGKEGTVDVTVTIRDNQP
                     ENVTISGQAVILFHAEWAITF"
     gene            complement(24246..24926)
                     /gene="narI"
                     /locus_tag="OPY25_001570"
     CDS             complement(24246..24926)
                     /gene="narI"
                     /locus_tag="OPY25_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HCS0927212.1"
                     /translation="MIQYLNVFFYDIYPYICATVFFLGSWLRYDYGQYTWRASSSQML
                     DKRGMVIWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPIAVKQQMAMILGGVCGVLT
                     LIGGAGLLWRRLTNQRVRATSTTPDIIIMSILLIQCLLGLSTIPFSAQYPDGSEMMKL
                     VGWAQSIVTFRGGSSEILNGVAFVFRVHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRTRR"
     gene            complement(24923..25618)
                     /gene="narW"
                     /locus_tag="OPY25_001571"
     CDS             complement(24923..25618)
                     /gene="narW"
                     /locus_tag="OPY25_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HCS0927213.1"
                     /translation="MQILKAIGLLMEYPDDELWECRDEALALIQHDAPMLANFTRELL
                     YAPLLDKQAEWCEVFDRGRATSLLLFEHVHAESRDRGQAMVDLLSQYETVGLHLNCRE
                     LPDHLPLYLEYLSVLPEAEAREGLQNIAPILALLGGRLKQRGAPWYQLFDALLTLAGS
                     TLTSDSVTKQIVQESRDDTRQALDAVWEEEQVKFIEDNATTCDSSPLHHYQRRFSQDA
                     APQYVDVSAGGPK"
     gene            complement(25618..27162)
                     /gene="narH"
                     /locus_tag="OPY25_001572"
     CDS             complement(25618..27162)
                     /gene="narH"
                     /locus_tag="OPY25_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HCS0927214.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQQEWQGGWVRDVNGKIRPRLGGKMGVISKIFANPVIPQIDDYYE
                     PFTFDYQHLHTAPESKHQPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     DNIQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEHETDLYERQCDVFLNPHDPAVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPHNGNILPAVETLRIPVQYLAN
                     MLSAGDTGPVIRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVQQVEEMYRYLAIA
                     NYEDRFVIPTSHREMARDAFPERNGCGFTFGDGCHGSDTKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            complement(27159..30887)
                     /locus_tag="OPY25_001573"
     CDS             complement(27159..30887)
                     /locus_tag="OPY25_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HCS0927215.1"
                     /translation="MSKLLDRFRYFKQKGDTFADGHGQMMHTNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGASYSWYLYSA
                     NRLKYPLVRKRLIELWREALSRHSDPVLAWESIMNDPQKCQSYKQVRGHGGFIRSNWK
                     ELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFYDWYC
                     DLPPASPMTWGEQTDVPESADWYNSAYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTIA
                     ITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFLNYCRRYTDMP
                     MLVLLDERADGSYVPGRMMRASDLVDGLGEANNPEWKTVALNSTGELVAPNGSIGFRW
                     GEKGKWNLEPVAAGVETELSLSLLGQHDDVAGVAFPYFGDNENPHFRSVRQEPVLVRQ
                     LPVKRLALADGSERMVVSVYDLVLANYGLDRGLDDGHSANNYNDVKAYTPAWGEQITG
                     VPRRHIETIAREFAETAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLVFCGCVGQT
                     GGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHASQWRYEKLTAQEL
                     LSPLADPTKFTGHLIDFNVRAERMGWLPSAPQLNLNPLSVKASADKAGLSAADYTMQV
                     LKSGAIRFACERPDSGHNHPRNLFVWRSNLLGSSGKGHEYMLKYLLGTDSGIQGEALG
                     SSEGIKPEEVEWQSAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMNTSDM
                     HPFIHPLSAAVDPAWESKSDWEIYKGIASAFSEVCVGHLGQETDVVLHPLQHDSPAEL
                     AQPFDILDWRKGECELIPGKTAPNIVVVERDYPATYERFTSLGPLLDKLGNGGKGIAW
                     NTQDEVDFLGKLNYTKHDGPAKGRPRIDTALDASEVILALAPETNGQVAVKAWQALGE
                     MTGREHTHLAINKEDEKIRFRDIQAQPRKIISSPTWSGLESEHVSYNAGYTNVHELIP
                     WRTLSGRQQLYQDHAWMRAFGESLVAYRPPIDTRSVSEMREIPPNGFPEKALNFLTPH
                     QKWGIHSTYSENLLMLTLSRGGPIVWISEADARELGIEDNDWIEAFNANGALTARAVV
                     SQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQLAYGF
                     NYYGTVGSNRDEFIMIRKMKNINWLDDEGRDQVQEAKK"
     gene            complement(30979..32367)
                     /locus_tag="OPY25_001574"
     CDS             complement(30979..32367)
                     /locus_tag="OPY25_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NarK family nitrate/nitrite MFS transporter"
                     /protein_id="HCS0927216.1"
                     /translation="MTRQNENYNRYLLSDWRPENPAFWENKGKGIARRNLWISVSCLL
                     LAFCVWMLFSAVAVNLNKIGFDFTTDQLFLLTALPSLSGAILRVPYSFMVPLFGGRKW
                     TVLSTVILIIPCAWLGFAVQNPATPFGVFILIALLCGFAGANFASSMGNISFFFPKAR
                     QGSALGINDGLGNLGVSVMQLIAPLVIFLPIFTFLGVRGVPQPDGSLLALTNAAWIWV
                     PLLAVATLAAWFGMNDIGSSKASVASQLPVLKRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILQLAFFGPFIGALARSAGGVISDKFGGVRVTLINFIFMALFTALLF
                     LTLPGSGAGSFSAFYLVFMGLFLTAGLGSGSTFQMIAVIFRQITLYNVKLRGGSDEQA
                     QREAVTDTAAALGFISAIGAVGGFFIPKAFGTSLALTGSPVGAMKIFLLFYIACVLLT
                     WLVYGRLKPKQQ"
     gene            complement(32582..33160)
                     /locus_tag="OPY25_001575"
     CDS             complement(32582..33160)
                     /locus_tag="OPY25_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCS0927217.1"
                     /translation="MSYLNRDERREVILQAAMRVALAEGFAAMTVRRIASEADVAAGQ
                     VHHHFSSAGELKALAFVHLIRTLLDAGQVPPPATWRARLHAMLGSEDGGFEPYIKLWR
                     EAQILADRDPHIRDAYLLTMQMWHEETVTIIEQGKQAGEFTFTANATDIAWRLIALVC
                     GLDGMYVLGIPEMADPAFKYHLDRMITLELFA"
     gene            33278..34765
                     /gene="smvA"
                     /locus_tag="OPY25_001576"
     CDS             33278..34765
                     /gene="smvA"
                     /locus_tag="OPY25_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl viologen efflux MFS transporter SmvA"
                     /protein_id="HCS0927218.1"
                     /translation="MFRQWLTLVIIVLVYIPVAIDATVLHVAAPTLSMTLGASGNELL
                     WIIDIYSLVMAGMVLPMGALGDRIGFKRLLMLGGTLFGLASLAAAFSHTASWLIATRV
                     LLAIGAAMIVSATLAGIRATFCEEKHRNMALGVWAAVGSGGAAFGPLIGGILLEHFYW
                     GSVFLINVPIVLVVMGLTARYVPRQAGRRDQPLNLGHAVMLIIAILLLVYSAKTALKG
                     NLSLWVISLTLLTGALLLGLFIRTQLATSRPMIDMRLFTHRIILSGVVMAMTAMITLV
                     GFELLMAQELQFVHGLSPYEAGVFMLPVMVASGFSGPIAGALVSRLGLRLVATGGMAL
                     SALSFYGLAMTDFSTQQWQAWGLMALLGFSTASALLASTSAIMAAVPAEKAAAAGAIE
                     TMAYELGAGLGIAIFGLLLSRSFSASIRLPAGLEAQEIARASSSMGEAVQLANSLPPT
                     QGQAILDAARHAFIWSHSVALSSAGSMLLLLAVGMWFSLAKAQRR"
     gene            complement(34790..35168)
                     /locus_tag="OPY25_001577"
                     /pseudo
     CDS             complement(34790..35168)
                     /locus_tag="OPY25_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460532.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GFA family protein"
     gene            35284..36414
                     /locus_tag="OPY25_001578"
                     /pseudo
     CDS             35284..36414
                     /locus_tag="OPY25_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460529.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
     gene            complement(36407..37417)
                     /gene="adhP"
                     /locus_tag="OPY25_001579"
     CDS             complement(36407..37417)
                     /gene="adhP"
                     /locus_tag="OPY25_001579"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HCS0927219.1"
                     /translation="MKAAVVTQDHQVDVTEKTLRPLRHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNTGNETL
                     CRNVKNAGYTVDGGMAEECIVVADYAVKVPEGLDSAAASSITCAGVTTYKAVKISHIK
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDGQLKLAEEMGADLTINSRTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPEAMNLDIPRLVLDG
                     IQVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLEDINVIFKEMEQGQIRGRMVIDF
                     RR"
     gene            complement(37699..39396)
                     /locus_tag="OPY25_001580"
     CDS             complement(37699..39396)
                     /locus_tag="OPY25_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCS0927220.1"
                     /translation="METTTKKARSLYIPYAGPVLLEFPLLNKGSAFSVEERRNFNLSG
                     LLPEVVESIEEQAERAWLQYQGFKTEIDKHIYLRNIQDTNETLFYRLVQNHLEEMMPV
                     IYTPTVGAACERFSEIYRRARGVFISYPNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRHPRI
                     TDDEYYAFVDEFIQAVKQRWPDILLQFEDFAQKNAMPLLTRYRDEICSFNDDIQGTAA
                     VTVGTLIAASRAAGSQLSEQKIVFLGAGSAGCGIAEQIIAQTQREGLSEDAARQNVFM
                     VDRFGLLTDRMPNLLPFQAKLVQKCDNLQHWDTENDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFSPVI
                     WKDKVYPIAQCNNAYIFPGIGLGVIASGASRITDEMLMSASETLAKHSPLVNNGEGLV
                     LPALKDIQVVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWKPEYRDYRRTSI"
     gene            complement(39573..39716)
                     /gene="sra"
                     /locus_tag="OPY25_001581"
     CDS             complement(39573..39716)
                     /gene="sra"
                     /locus_tag="OPY25_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HCS0927221.1"
                     /translation="MKSNRQARHILGLDYRISNQRKVVTEGDTSSVVNNPTGRKRRAD
                     SQK"
     gene            complement(39811..40026)
                     /gene="bdm"
                     /locus_tag="OPY25_001582"
     CDS             complement(39811..40026)
                     /gene="bdm"
                     /locus_tag="OPY25_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HCS0927222.1"
                     /translation="MFTYHSANTSAAQPALVNAIEQGLRAELGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
BASE COUNT         9628 a        10441 c        10675 g         9460 t
ORIGIN      
        1 tttgttgtaa cgattagctg acgggtttat ttccagttag gtgataaaat tataaaaacc
       61 tgcgaggagg ctcaaaatga agaaatcaga tggtgaaatt cacgaaaaga cagcatcctg
      121 gggcattttg cagtcagaat ggctaagaaa atgtggacgg ctattattgc tgttacttta
      181 ccgtttcgtt atcggatggg cttttttcca gttacttgcc atgatcgtgg cagggatatt
      241 tttgttaggc gtcttattat ttcatcccat aatatttgta cagactatcg caattactga
      301 gaagttaaat catgcttcgc ttgatttatg gcatatcctt aagttatgcc tgtggcatta
      361 cggtatcatc gcagggttta tttttatggc ggagtgtacg ttaagtaaaa gtatacggca
      421 ggttcagcgc ttgtccaaaa aatttggggc acaggatttt tcttcacgcc cgtgatccgc
      481 cgctgcaacc tgcggtctta ctgaataatg gctatgacca gcagaccgaa ttatctcggt
      541 tcgaggggga ttctatgtgt ttgcacaact gcagtgaatc gtaatttcag tgcattatcg
      601 ccgacaatcg acgtgttcct cactaattgc cttcctgact atatagtggt cttatctttg
      661 gcgaaacaat gttatttagt tatggaaggc gacaacaact gtactattga ttatcaaata
      721 tcctttctgg tcaggtagac tcgcctttgt gaaaacatat cgttatctgt gctcctgggg
      781 actcactccc ttgccgcctt taagcaactc gaattatttt gggtatagaa caggcggcgt
      841 aatggccata ataagcaaaa tataacctct ccgtttgtaa taaggcacag attacagggg
      901 gggaatgatg tttattttaa ccatctgttt aagcgctgtc cgctaatctt tacctgctca
      961 aatacataat cacccctgtg actctcgcga ggtgtaacat atggtaaaat gcgtatcttc
     1021 tttcctcctg ttcagcctgt tgtccgttca ggcaatatca gctgaaaacc atattgatct
     1081 ccaccagcca aaagactttg tcgatattac tacggtcgcc cccgacgtac aggtagacat
     1141 gcgatacttc acttcccata actttattgg tcgccccatt aaaggctata acgcgcctgt
     1201 ttgcctgtta acacgaccag ccgcgaacgc agtaaagcag gtcgccgatc gtttacgccc
     1261 cttcggactt accttaaaaa tatatgattg ctaccgtccg caaagcgcag tgaatgactt
     1321 tatcgcgtgg gccaaagatc cttctcaaaa ccaaatgaaa aacgaatttt atccgcaggt
     1381 agagaaaaat cgtttgtttg aggaaggtta tcttgccgcc agatccggcc acagtcgggg
     1441 aagtacgctt gatctaacga ttgttccact tgacagtaaa ataccgatat accatcccgg
     1501 acgaccactg gtgaattgta ctgcgtccgc ggcgcaacgc tcgccagata atagtctgga
     1561 ttttggtaca ggctttgact gttttagtcc gttatcccat cccgataatg tcatgcttac
     1621 cgctcagcaa cgcgcaaata ggttgttatt acaaacattg atgcgtgatg cgggttttac
     1681 gccactggat actgaatggt ggcacttctc ccttactcat gaaccatacc cgaacacctg
     1741 gtttgacttt cccgttaagc agagaccctg aaacggcgtt ttgttgcgaa atctaatcat
     1801 tacgcctgtt ggaaagcacc ataacagtta gcaaatcatt gttaatttta acaactgata
     1861 tacactgcgg ttgccacctg caagcagcgc tcaatgagaa cgaataatga aaaaatatca
     1921 acgtctggcg gagcaaatta gagaacaaat cgcctctggc gtttggcaac ccggcgatcg
     1981 attaccctcg ctgagggagc aggtcgccag tagcggcatg agttttatga ctgtcggtca
     2041 tgcgtaccag ttgctggaaa gtcagggacg gattatcgcc cgtccgcaat ctggttatta
     2101 tgtcgcgccg catccggttt gtcggtcagt cgcgacggca gcgcacgtta ttcgggatga
     2161 agccgtagat atcaatacct atatttttga gatgctgcag gcgagccgtg atacctctgt
     2221 ggtgcccttt gcctcagcgt ttcccgatcc gcgtctgttt cccttgccgc aattgaaccg
     2281 ctctctggcg caggtcagta aaaccgagac ggcaatgagc gtcatcgaaa acttgccgcc
     2341 aggtaatgca gaattgcgct atgcgatagc acgccgttac gcgcagcagg ggattaccgt
     2401 ttctcctgac gagattgtca ttaccgccgg cgcgctggaa gcgttgaatc ttagtttaca
     2461 ggcggtgacg gcaccgggag actgggtggt ggtggagaac ccctgtttct acggtgcgct
     2521 acaggccctg gagcgattgc gcctgaaagc gttgtcgata cctaccgatg ttaaagaagg
     2581 tatcgatctt atggcgctgg aacaggcgtt acaggaatat ccggtgaaag cgtgctggtt
     2641 aatgaccaac agccagaatc cgttagggtt cacgctgagt gctgagaaaa aagcgcggct
     2701 ggttgcgtta ctcacgcacc ataacgtgac gctaattgaa gacgatgttt atagcgaact
     2761 ctactttggc cgcgagaaac ctcttcctgc caaagcatgg gatcgcgacg ataccgtgtt
     2821 gcattgttcg tctttttcca aatgtctggt tcccggtttt cgcattggct gggttgcggg
     2881 aggaagccat gccagacaaa ttcagcgttt gcagttaatg agcacattat ccaccagttc
     2941 tcccatgcaa ttggcgttag tagattatct ctcgacacgt cgatatgacg cgcatctgcg
     3001 ccgattgcga aggcagcttg ccgaacgtaa acagcaagcc tggcaaaccc ttttgcgcca
     3061 tctcccggcg gaagtaaaaa ttcaccataa cgatagcggt tattttcttt ggctggagct
     3121 acctgagcag cttgatgccg gcgaacttag cgccaaagcg cttgaacacc ttatcagtat
     3181 cgcgccaggg aaaatgtttt caacgtccgg cgcctggacg cgtttctttc gttttaacac
     3241 cgcatggcat tggggagaac gggaagaaca ggccgtaaaa cagcttggaa gcctgattcg
     3301 cgagatgctg agcgctaaaa gccttgtgtg aggtggaatg cgtgtcagct cacaacctga
     3361 ctaaatttcc cgagtgtgcc gggtgagcat ctggcgcgcc gtctattttt aggaaagcgg
     3421 cggcccgttc gccggaaatc gattaatgac gatatgggaa aatgctatgc aatatcaatt
     3481 actgattaat ggcgtgctgg tggacggcga gggagaaagg cagtccgttt ataacccggc
     3541 gacaggcgag gtcatacttg agattgcgga agcgtcgccc gtgcaggttg acgccgcagt
     3601 gctggccgcc gatagcgcgt ttgccgaatg ggggcagacc acacccaaag cacgggcgga
     3661 atgtctgtta aaactggcgg acagcatcga gcaaaacgcc cttgagttcg cccggcttga
     3721 atcgcaaaac tgcggtaagc ctttgcactg cgtaattaat gatgaaattc cggcaatcgt
     3781 ggatgtcttt cgcttttttg ccggcgcggc ccgttgtttg agtgggctgg cggcgggcga
     3841 atatctggaa ggacatacgt cgatgatccg ccgggatccg attggcgtgg ttgcctctat
     3901 cgcgccgtgg aattatccgc tcatgatggc ggcctggaag ctggcgccag cgctggcggc
     3961 aggtaactgc gtggtgatta agccttctga aatcacgccg ctgacggcgc ttaaacttgc
     4021 cgcgctggcg aaggatatct ttccgccggg ggtgctcaat gtcctgttcg gacgagggca
     4081 aactgttggt gatgtattga ccggccatga aaaagtacgc atggtctctt taaccggttc
     4141 tatcgcgacc ggggagcata ttctgcgcca tactgcgcca gcgataaaac gtacgcatat
     4201 ggaactcggt ggtaaagccc cggtgattgt ttttgatgac gccgatctgg atgcggtggc
     4261 gcagggtgtc cggactttcg gtttctataa tgccggacag gattgtactg cggcgtgccg
     4321 tatatacgcg cagcgcggta tctatgatgc gctggtcgaa aagctaggga acgcggtgag
     4381 cagcctgaaa atgggcgcgc cggaggataa gtcgacagag ctggggccgt taagttcgct
     4441 ggcgcacctg aagcgcgtca cagcggctgt agaggaggcg aaggccctca gccatatccg
     4501 tgtgattact ggtggaagtc aaacggaagg taaaggttac tatttcgctc cgacgttgct
     4561 ggcagacgca aaacaggaag atgccatcgt gcaacgcgag gtcttcggcc cggtggtcag
     4621 tataaccgtc tttgatgatg aagatcaggt tctgaggtgg gccaacgatt ctcgctatgg
     4681 tctggcatcc tccgtctgga ctcaggacgt cgggcgggcg caccggctta gcgccagatt
     4741 gcagtatggc tgtacctgga ttaataccca tttcatgttg gttagcgaaa tgccgcatgg
     4801 agggcaaaaa cagtcgggat acggcaaaga tatgtcattg tatggtctgg aagactacac
     4861 ccttgtccgc cacatcatgg ttaagcatta aggatcattt actgttcaga aaaatcgtga
     4921 aaaaataggc gggtgtcggc ggagaggggg acctccccgc caacatgcgc agcaagtact
     4981 caaaggttga acacctcaag caaaccagcc gaatctcaac gagatcagac ccaaaagtcc
     5041 tgcagcagca aagacattaa tcagcacgac ggttttactg gaaacattca ttttcgccac
     5101 ctttcatcat aacccctatg ggtatagtac gggttggcga gatccgcaat aatacgtaaa
     5161 caggatattc tgtgagcgga gccgtgcatt gagaacgttt tgctgttaag gctgataaac
     5221 cttgatgtgt gtcaaataaa aagagcatat tgcgcgcgtt ttttcctctg gttggcgcga
     5281 catggccgat aagtttcccc gtcgcattgc tgttttcgct tttctgacct caagcccgat
     5341 acaggttacc gggcatggtt tttccgccag gtcaggctat cagggcaatt aattgcgctc
     5401 tgtctacgtc ggtaacgtcc tgcggatgcc gatatcctgc gttctcattg gccagggtat
     5461 acagcgcaac aagccagtca tagacatagc ggctggcggc gtgaacgggc tgttcgtcaa
     5521 gctttgttag acgcaacatt gtcgaacgcg gcgttgcggc gaaaatggct gcgcctttct
     5581 gaacgcggct ggccggacgt tgggcctcct cgatattggc gtagccgagc caggcgatga
     5641 agttaccaat gatggcatga agctgcgcgc cgctcacctc ctcgcgctgc atggttttct
     5701 gtaactgctg aggtaaaccg aggcgatagc tggcggtaat taaaatctcc gccacggcgt
     5761 tgagcatctg cggttccagt cccagacgct gcgcattatc ccggcagtgg gcccactggc
     5821 gcagatgatt gatccacatt ttgtgcgcct ggtagcctgt ttcatgacct tctgacgcta
     5881 aagcgtgcgt tggttcgtcg gcaaagagat cgatcgcgtc attaaataaa ccgctgacct
     5941 gttcttctcg cgactgtcgg gtgcgcagca acgcttcgaa attctgtacc ggcggtaaca
     6001 gcccggccag caggtcgcca tgtctggcgg cctgggcctg aagacgccgg atcacggttt
     6061 caaccggtag ccgcgcgtca tcacacatcg gtaacagatc gcgcacgcgg cctcgcagtt
     6121 gttcgcgtaa cgcctgtaag cgcgcctgtc gctgtggtgc cgatgtcgcc tgcgataacc
     6181 actccaccaa acgctgcata ctgtgtttat ccagcgcctg caacgttccc caatgcacgc
     6241 caggtttacc catcaactgc tggacggctt catccagatt ttgctgggtg gcaaaacggg
     6301 catcctgtgg agtaatagcc cagacgacgc cgggtaacgc tgattcatgc tgcggctgcg
     6361 tggcgttaac ccactccagt aagtgacggg cggcagtgga cgtttgcgag cgagatgcca
     6421 gagcattgca aatcaccaga acatcgggct gtatctgctg acggtaatgg gccagcatcc
     6481 agcctaattt cgcccgccat aacggatgag gatgactgtc tggcgcgacc ggaatatcca
     6541 gtaaatcaac gttatccagt acgctatttt caacggttag caccagttcg cgggtaagca
     6601 gcgccagaga atcaagcgaa aggctgaccg cattgagcag tcggccttcc ttaaccggat
     6661 gcaccaccac atcgctttgc gtatcgctgg cggttagcgc catttgcgtc aggaagtttt
     6721 ccgccggtaa gccaaaatga tcgaccagca ggctgagcgg cgccgccagt tccccggcat
     6781 ggccggtttg ttgcaacata tgcgccagcg ccagccattg ctgggtgatc tctggttgct
     6841 ctccccacag taatgcccag gcgtgcgccc gtgtcgtgag atccagcgca ggcaagagcg
     6901 aggcaaagtg ttgccatgtc gcatcatcaa tatgttgtct ggcggacggg aggcaagagc
     6961 gccagaaact cgcgatggtc gctacctctt cagcggtaac gccggggacg ggctgcggtt
     7021 ggcgaagcga ttgccatttc tccaggcgtg atgtgataat ggatttttcg acctggcgac
     7081 aaacggggga cgagctggtc caggcaataa agatctgcac cagttcggct tcactgatca
     7141 agcgcaggcg caacggccag ccgctctcgt ttgaaaaaat gtcgcgcgta aagcgaatag
     7201 ccatattcgc tggcgcatga cccggattga tgtggctgaa ataatcatag tcacggtccg
     7261 gcgtgataat ttccagcttg ccattctcgt taccgcatag cgtcgttaac agatgcgctt
     7321 ttgcggattg cgcatacccg tacagaccaa cgcagccatg tgatgatgcg caggcggcgt
     7381 tgagcgctga ctcatccgcc gcggcaagcg taagttgcgc cagcagagcg tcggcttcgt
     7441 catccagtcg cgttgcgtaa cggcgcgtgt tgttaaccca ctcgataaca gcctgagtgg
     7501 cgtttaacgg ttttgtcatt tcaggtatac actcccgcta tctatccagt agtggctgcc
     7561 gctgtggcgg cggtcagcca gcgtattcaa ttttaatgtc agcgcatcgg cggcgaccgg
     7621 cgtcccgtcc tggagccagg catcacttaa tatgaacgat tccggggcgc tatctttgct
     7681 actgccgcgt aatttcagtc ggacattcag tacgccgtcg ccagcgatgg ttttcgccag
     7741 ttcggcggaa ttaatgctca ggcaatagag tggggtcgca ggccagcgac tgttcgcaag
     7801 ttgacgaaag cccaacgtca cgttgccgcg tagcggaaaa tgcaggcgtg cgtccagcgt
     7861 tgcgccgggt ttatccaaat cgatctcgtg ataccagatg ttttcatcgc gaagcgtatt
     7921 aacggtatta tccagtacgc cgagataacg cacagtcgaa tacgcgccga tatcagccgc
     7981 tttaaaattg aaacgcggca ggcgtaagtc cagcgccagg ctgcataaca tcgcgcccac
     8041 cgcggcagtg gattttggat tgccgatacg cccttgttga ctgaagggat accattcatg
     8101 tacctgatac ttatccatcc acacaatgcg attaaccggc accggttgta agtgccggat
     8161 gagcgcctgt acgccaggta aacaggtcgg tctccccgtc accagcaaga tatcgcagtg
     8221 atagtgggag atcgcttcgc agaccgcatg aagcggcgtt gtcagcgtaa actgaccggc
     8281 cagcagagcc tcctgaagct ggctaaactg gatttgcaat ggcacattga atatatcaaa
     8341 tgtcggcgaa ccagacggta aggcatgatc gatcgcctgc tggatatagt tcatcacgtt
     8401 gctcgttggg cggcggatca gcagatcgcc aaatgtcgca tgtaaaccgg caaacggatc
     8461 gttaatgtcg ctttgctccc aagcggaaag taccgcgtgg cccagcggca taaataattg
     8521 cagcgccgtt tgctggcgca aaatggcctg agtatcaatt cgtcccgaat cgccaaataa
     8581 ggtcgccagc agggcggcgg catccgtaac gcctgcccgt tgcaacgccg tttgcaggga
     8641 agggagtacg cagcgctgaa tgatatccaa tagcagatcg tccccggcga ctttaaaacc
     8701 ttcgcgaaac aggagatgag gcgtaatttt tacattggcc cccacgccgt catctaactg
     8761 atagtgaacg atcgccatat ccgtcgtgcc gccgccgata tcaatcgatg ccacgcgcaa
     8821 cgcgcgtccg gggacgacgc cgggttcagg ctggcgatcc ggtctggcca gcgcattaaa
     8881 aaaggattcg gtacgcccgg cgtaatgcga aatggcttcg ttataaagcc ataccagttg
     8941 gccacaactt gcttcgtccc attccatctg tatttcaggt actggcacca cgcttttttc
     9001 acgctgctta ggcgtggtga aatcctcatc ctgcggatgc cagcccatgg ctttccagac
     9061 cagcgccagc gcttcaaaca ttcgctggcg gaaaatttct cgctcctgtt tcggcatggc
     9121 ggaaggcagc gttaaaatca gggtacgtag ctggcgcggc gaggcgggaa agccgagccg
     9181 cagccgggtg gcgacgctgt taatttgccc cagcgcctga gccagaattt cgcacaacat
     9241 atgcgtcatc aaggtgctac ggctgtattg cggcgaaaaa accggtagcc tttcttcatg
     9301 cggcaggcgg aataacggct gtccgtcgtc gttcatcaga ttcatcagcg gaaacgcggt
     9361 ggcaagcggt tcgcgctgcg ttttaccgtg gatctggcta aagcgccagt cctgcaaggc
     9421 gggggtttca tcccacaggt agcggcgcgg gctggagata ccgctgctgc cttcggtgcc
     9481 cacacgctgc atagcaaggg cgcgagcctc gtcgcccaca cgcacaatag aaggccagac
     9541 aaaggcgtcg tctcgtccgc tttcgacaga aaagtgttgc ttgccaaagc gcgcttctga
     9601 gaattccacc cggctggtaa ataaaggatc gttcagatac tgcggctcgc ttaaagaacg
     9661 cacctgaagc tctgccgtct ggcgtaagcc gtcattcgca tcgccatgat cctcgatcaa
     9721 gacgccgcag gtatgcgtat tgccgacatc cagaatcaga tcgaccggga ttgcgggcgt
     9781 gcttaacgta tgtgtcacaa actttacttc cggcaccgta agctgttcgc ctaacagcgt
     9841 cagtaaattc aaccagtgcg cctgatactc aaaactacgc agcgcttgtt gaatggcctg
     9901 ttccggacgg ttttccacct gtgaggcata ctgaagaaac gactcgcgca gccagccgtc
     9961 aatccatgtc tggtcaagaa aatcggcaac ttcttcatcg cgccaggcga gcgcaaaacg
    10021 tgtgccattg agcagatcgt tttcgcaagg cgccaacgcc gcaggcatat tttttgccag
    10081 ctgactgtcg aaggcgaggg tgatgcggtg tgtgtttccg gcgctatctg gctcgctgag
    10141 tttacgtacc tgaatgcgcg cccagttatc cggcccgtca ataaaggtac gcggcggatt
    10201 aaaacgcagg aacggcaggg gaagccagat cccgtcgagt acatccagag aatagtgcag
    10261 cgtctgagtg ctttccggtt tcacgacttc gggttggccg ccagcacgtc ctggcaacgt
    10321 gtagcgcccg ctggtcagat caaaatcgag gcgcagtagc gggccgtttg ccgttttgcg
    10381 cacaaaacgt ccgtagtggg ccgactcttg cggcgttaag ccaaaatcaa gaaactggac
    10441 gccactgttt gcaatgagcg tgacgctctg tttgtaatca cacagattga ccaacataaa
    10501 atcaggcacc tatcttttta aacgtcaacg gaattgccgc gtggtcgcca taacgggcgg
    10561 tacaggttgc gacgtcattg acgcctgctt tacaggtaat ttccggcatc ggataacgtg
    10621 aaccgtcggt gcagcgcgca ttgccgcgac ttttaatcat cagctcgccc gtttgatgca
    10681 gaccagagaa aatttccgcc cgacaaacca cgttatcgcc atgtactacg cgcgcgatgc
    10741 ctttgttatt ttggatctga taacgcagag agggcggctt gccggtaatc ggatctttga
    10801 catccacgct gacccgccag ctaccgttta aaaagcgcgt ggttccaagc ttcatctgcg
    10861 tattgtccat caccagcgcg tctttgggga tagcggcaat gataacaggc gcttccggca
    10921 gcggcgccgc tttgggggcg gacgtcacct cagcgcgatg cagcggcaaa tgcgcggtga
    10981 gttcaggcat tggggtaaca tcagttttcg cggtagcgac aggcgcggtg cgaacaggag
    11041 aggccccgtc aacggatgaa gatggccaga aaaaaggcgt ggcgacggcg gcgataacca
    11101 cggcagcgac aggtaagctc cacagcggta gacggcgagc tcttttcgcc tcagcaaccg
    11161 ggataggtgc ggcaggcttc ggctcgctaa cgataacggg cggcgcagca ggttcctccg
    11221 gcattttcgg cggctcaatg acagacgtta acaaaggttc atccgcctga ctaaacgccg
    11281 cctctaccag cggcttttct tcgggctgcg gctccggctc gaccagaggg atgtcggaga
    11341 tcgcctcggt tacccgcagg cagtccagca catcatcgcg tgtattttcg ttgagattaa
    11401 cgaatcccca gaaggtgata accggtttgc cgttaaccag gaaaacatga ttttcgccgg
    11461 gaaattgcgt cgccttctca agtagcgaac caaatagctg gagcgctgtt ttaccggatt
    11521 gcagactttt gcgactgagt gcagccgcgc tttcaaaagt gctggctaaa taacgtaaag
    11581 cccgagaacg tgtctcttcg tcagccgctt tccacgctat cgcctgacct tcaatcggcg
    11641 aataccagtc aacccgatcg ccattatcgt taagttgcgg aatcgccaga cagtcaacca
    11701 tcgtctgctg tttacgcaga cgaagcgttt cgcgaatttg caatgctgat tcaaatacgg
    11761 cctgaccgcc gccgcccacg gcctgataat catccagatt gccgctgcgc aagagagatt
    11821 ttgccacgtt gttatccctt agacttcttc acgcgtctac tttacggggt ctatacgcaa
    11881 gcaaacggcg gaagaaaggc aaaaaggcgc gaattctcgg tctattaagc cccgtgtttt
    11941 cacttgacgt aagttaaatc agagtggcgg cggcgaatga ccgcatcggg cgacaataac
    12001 gcgtataata ggcgaatcat gctattacag aataaagagt aggagagctt atgtcgcacc
    12061 tggaggaagt gagcgcccgc gtggatgccg ccatcgcgga gagcgtaatt gcccatatga
    12121 atgaattgct gattgccttg agcgatgacg ctgaattacg tcacgaagat cgttatgtgc
    12181 agcagcagcg tttacgcacg gctatcgcgc atcacggcag gcaatatcaa gaagatcggg
    12241 acgcgcgccg cgaacagctc accaaaggcg gcacgatcct gtaacccatt aaaactggcg
    12301 cttcgcaatc agccatgcgc caatgaccag caacagcgcg ccaaacgccg gcccgaccat
    12361 tgcgcgtaac gtgacgccgt ggctacgcgc aatatccagc gccagtccgc cgattaactg
    12421 actggcgacc agtaccgcga tagtcgtcgc ggcgccaacg ttctgatacc cgctaatgct
    12481 ggcaaataca aaaaatgacc ccagcaaacc ggggatcaat gtccaccagc gcacgctggc
    12541 gaccagctcg ccgaagcccg tagcgccttg cttaaaccac aatatcgtca caaataaaac
    12601 gatccctacc agcgagttca acagcatagc gatcagaatc gtcgatgatg tctgcgtaat
    12661 acgcaccata atactgtttt gtaccaccag cccgacgccg gcggcgatca aaaagataag
    12721 cgtcagcgac tggttcatca gcaggcgtcc ggcgcggcgt gttcatcaag ctggagctgc
    12781 ataaacgtaa gatctaacca acggccaaat tttacgccga cctgcggcat ttgcgcggtg
    12841 acggtaaatc ccagcgaatg atgcaggcgt atcgaggcgg cattctgtga ctcaataccg
    12901 gccaccatca catgcttgcc gcagcgtcgg gcttcgtcga tcagtctgct gagcagtttt
    12961 cgccccagtc ctttcccctg gtgcgccgga tgaacataaa ccgagtgctc gacggtatag
    13021 cgaaaaccgt cgaaactgcg ccaatcgcca aatgatgcat agccagtcac cacgccattt
    13081 tcttcgctta ccagcaccgg atagcccagt aattgacggg cctcatacca ggcaaggcga
    13141 ttatccgtat cgaccgtccg atcgttccag atggccgcag tatgtaatac cgcacggtta
    13201 tagatttcgg taatcgcggc gcagtctgct ttatcggcaa agcgaatcgt catagggaac
    13261 cccagggaat gtttacgata gtgttagaaa tactattgaa ggcggcataa atcaacgaat
    13321 tagcgcaaga attcatattt agcgagaggg gaaagaaagt cgttcataaa agcgcacagc
    13381 ctgatatctg agagtgttta actccctcag aaagctaatg ttcgactatt attgatggat
    13441 tatgccaggc atgaggagaa tagaatgaag caacagacca accgaaatcg tcgttgggtt
    13501 ttggcctcgc gtccccacgg cgcgccgcag atggataact tccgcctcga agaagatgac
    13561 gtcgcgacgc ccggtgaagg gcaggtgcta ttgcgtaccg tttttttatc actcgaccct
    13621 tatatgcgtg gccgcatgag cgatgaaccc tcttatgcgc cgccagttga acctggctgc
    13681 gttatggttg gcggtacggt cagtcgcgtt gtcgcgtcga atcatcctga ttaccgacca
    13741 gacgaatggg tgttgagtta caatggttgg caggattatg acatttcaga tggcgaaggg
    13801 ttggtaaagc tgggtgataa tccgcaacat ccttcctggt cgttgggagt tttagggatg
    13861 ccggggttta ccgcctatat ggggttactg gatatcggcc agccgaaaga gggcgaaacg
    13921 ctggttgtcg ccgccgccac cggccccgta ggcgcaacgg ttgggcaaat tggcaagctg
    13981 aagggctgcc gggtcgtggg tattgccggc ggcgcggaaa aatgccgtca tgcgacagac
    14041 gttttgggat ttgatctgtg ccttgatcat cacgctgata atttcccaca acagcttgcg
    14101 caggcctgcc cgcagggtat cgatatctat tatgagaatg tcggtggtaa agtctttgac
    14161 gccgtcttac cgctactgaa tacgtcggcg cggattccgc tctgcggtct ggtcagcggc
    14221 tacaatgcga caacgttgcc ggacggtcca gacagactgc cactgctgat ggcgacatta
    14281 cttaaaaagc gtattcgcct gcaaggtttt atcatcaacc aggactatgg tcaccggata
    14341 catgagtttc agcaagaaat ggggcgttgg atcaaagaag ggaaaataca ttaccgggag
    14401 cagattactg atgggctgga aaatgcgcca gaagcgttta tagggctgct ggcggggaag
    14461 aactttggca aagtcgtgat acgtttagcg gacgatgcgt aaagaaaaaa tggcggcatt
    14521 atgtcgccat aaaaatgtgc aaattttaaa attgcggctt tacttatatt catcattcag
    14581 atcgcggtgg ggcagcttat ctccctcagc ggcctgaacc ggtcaaaaat ctcgatacat
    14641 gaaggaatga cggagataaa acggttgcca taaagaaacc tgtattgttg taaaagatga
    14701 gaatatcacg caagtaaatt atcactttta tttatttggc cgttcaggtc tggattatct
    14761 tttttacaat taagttccga aacttcttcg ggactcgatt gcgatgttgt tctgccaaga
    14821 ggtgaaggaa ggaaaatgcc gggtacggaa aaaacacaac atataagcct gaccacacag
    14881 gttgaaaatc ggttaaagca tcaattgtct attggcgcat taaaaccagg cgcaaggctt
    14941 atcactaaaa atatcgctca agagttaggc gtcagtatta cgccggtgcg tgaggccctg
    15001 ttaaggctgg tctcttccag tgctttggcg gtggcgccag cacaggcgtt tatggtgccg
    15061 gagatctcgc tggaaagttt gctggaaatt aatacgattc gtactgccct ggaggagatg
    15121 gcggtggtcg ccgctgcggg taagattacc ccggatcgcg agcagacgct gaatgcgcta
    15181 ttagatgaat ttcaacaggc gctggaaagt ggcgttatgg agaaaattct tttggccaac
    15241 cgcgcattcc gctttgagat ctaccactac gcggatatgc caacgctgta tgccatgatc
    15301 gagcaattat gggtacgcct ggggccaagt ctgcattttt tatatgataa ttttaaactt
    15361 gatgattatc aaaacggcgt taatctgtac agaaaattgc ttaatgcgtt agtgactggt
    15421 gataaagaag ccagtcgcca ctgcctacag aacgttttgc aacaaaacgt agcgacgatt
    15481 aaaaatcagt acttcatgta actttcatga aactatgact aatcaatagc ggggatgccc
    15541 cgctattgcc ggatatttat tcaaattgcc atgccagatt aatccccacg ccatagttac
    15601 gccctggcgc tggctcataa tatcggccat tagattcatt aacgatcacc gaaccgatat
    15661 attcttcatc aaatagatta tctacccgcc caaaaatatc gacggtaagc tgactgtaat
    15721 taaatttata ccctgtattt agtccaacaa cggtatacga aggcgctttg gcggtatttt
    15781 catcattggc catgatatcg cccatatacc gaacgtctgt tccggcgtac cacccctcat
    15841 ccgggataaa acctaatgag gcgaatccca tattacgggc gatgccgggc atccggtttc
    15901 catcacagtt ttgcccctga caaacgttac tgcgataggt cgcatccagc caggtccatg
    15961 atgctttcac ccgccagtcg ccggcgaagc gctggtccaa cgcgagctct gcgccctggc
    16021 ggcgcgtttt gcccgcgttt ttgtaggtag tgcgtcctcc catactactg gcgacgacaa
    16081 tttcatcatc ggtatcggtt tgaaataacg cggcggtcaa caagccattg ccaatccgcg
    16141 ttttactgcc gacttccacc gtatcattgg tcgacggttt gaggtcaaag ttgaacccgc
    16201 tttggccgtc agcgcgataa gaaagttcat tgatagtggg agtttcaaat ccgcgaccgg
    16261 cagcaagata gagattccag gcgtcagtta acgcatattt tagcgatccg gcgggtagcc
    16321 agtggtgata gctggcgtcg ccgctgtcat cgccattgcc gggcgcgata tagtgatcgt
    16381 tagaatcgaa ccacacggaa ctgtagcgca cgccagcatc cagcgagagt ttttgcgtaa
    16441 gctgccactg ggtttgcaga taaggatcga cattccacat caggttacgc tcatcccgcc
    16501 gtaaatcgcc tttatgcccg aactcagggg tgccgttgtt gagacggaaa ttattgtaac
    16561 ccttgcggtt ttcgctcatg ttttcatagt ttaacccgcc agtgaaggtg accggcacac
    16621 ctaattctcc ccggtgagtc cagcgggaat caattccctg atagtggcgt tgcagtgtaa
    16681 ttacgccgcc agcctgggct ggttttagct gtgccaccag gggaatagac tggtattgcg
    16741 tggtttcccg ctctccggcg taggccatca cgctgatatc atcctgcgcg ctgagctgac
    16801 gttcataacg caatcctgcc tgagtttgtt tgatggtttt acgcgtattg tactgttcag
    16861 cgcgcggcgc ctgctgcgga tcggctttcc attcagattc ggtaagtccg ccgggatcgt
    16921 ccgccttaat gtccacacta ttaaaaatca gcgaaagttt actgacatcg tcaaggcgca
    16981 cgcccagttt ggcattagcc agattttttc gcgcgccgct gtgatcgcgg tagccgcggg
    17041 tggtgaaacg ggtagtcgat accgtgtaat ccacgtcgcc aggctgtgtg ccgtccccca
    17101 tcgcgcccgt ggcttttaac ccatagcgcc agcttccata actgccgtag tagctgctgg
    17161 cctcaagggt gggcggctgt ctcccggttt cggtggtgac atttatcacg ccgccggaag
    17221 cattgccgta tagcgctgag aaggggccgc gtaacacttc aacgttttgt atgctgttaa
    17281 tatcaatatt tgaaatctgg ccttgtccat ccggcatggt ggcgggaatg ccatcaacat
    17341 acagacgaat gccgcgcacg ccaaaggcgg aacgcgagcc aaatccacgg atagagattt
    17401 gcagatcctg cgcgtagttc tgccggttct gcacctgcaa tcccgggacg ctggttaaag
    17461 actcagataa attaacgcgc ggcgtcgcca gacgcatgtc ttctccctca atgacgctaa
    17521 cggcggcagg tgtatccagc tcggatacgg tttgcggcgt tgcggtgact atcatggttt
    17581 gttcattggg cgcgctggcg gcctgaagga ccggggagaa ggtcagaggc aataagaggg
    17641 cgggataaag tcgctgtcta acggaaataa ttttcatgaa aatgccggat aaatgtaagc
    17701 gtatcaacgg aaaacgtgac attaagggta gtcaatatgt aaagttttga aattttaatc
    17761 gcacattaag ttaagaaaat gtgcggtatt taagagccat gacattcgca ggcgaggaaa
    17821 agctccactt tctgataaat aatgattatt attctcaact tataataagt gcggaacgaa
    17881 gatcccgcgc agcgaagtag tgtgaagcag ctatacacgt ttttatcaaa aggagtcgtc
    17941 atgcacttac gtcatctttt ttcgccgcgc ctgcgtggtt ctttattgtt aggttcgctc
    18001 ctcgtcgcat cctcatttag cacgctggcg gcggaagaca tgctgcgtaa agcggtaggc
    18061 aaaggcgctt atgagatggc ctggagtcag caagaaaacg cgctctggct ggctacatcg
    18121 caaagccgta aactggataa aggcggcgta gtttatcgtc tcgacccggt gacgctggaa
    18181 atcacgcaag cgattcataa cgatctcaag ccgttcggcg ccaccatcaa tgccgcgacc
    18241 caaacgctgt ggtttggcaa taccattaac agcgcagtta ccgcgattga tgccaaaacg
    18301 ggtgatgtaa aaggtcgtct ggtacttgat gcgcgcaaac gtactgaaga ggttcgtccg
    18361 ttacagcccc gtgagctggt tgccgatgcg gcgaccaaca cgatctacat tagcggtgtt
    18421 ggtaaagaga gtgctatttg ggtagtggat ggcgaaacca tcaaactgaa aacgacgatc
    18481 gaaaataccg gcaaaatgag tacgggtctg gcgctcgaca gtaaagcaca acgcctgtac
    18541 accaccaatg cggatggcga atttatcacc atcgataccg ccagcaataa aattctcagt
    18601 cgtaagaagt tgctggatga cggtaaagaa cacttcttta ttaatctgag tctcgatacc
    18661 gcaggtcatc gcgcgtttat caccgactcg aaggcaactg aggttctggt tgtcgatacc
    18721 cgtaatggca atattcttgc caaaatcgcg gcgcctgcct ctttggccgt cctgtataat
    18781 ccgacacgta acgaggcgta tgtgacgcac cgtcaggcag ggcaggtcag cgtgatcgat
    18841 gcgaagacct ataacgttgt taaaacgttc gatacgccga cgtacccgaa tagcctggcg
    18901 ctatcggcag acggtaaaac gctctacgtc agcgtgaagc agaaatcgac acgtgaacaa
    18961 gaagcgacgc agccggatga tgttattcgc attgctctgt aaatagggta tggaggggga
    19021 aacccctcca gtcatctctt taaacgcacc gatacgcctc gttaaacccc gccgatagcc
    19081 tgatgattct gtgagaatta cactaccttt ttgcagtcgt taactcatta tattcacgag
    19141 gaaaatatga aaaagttatt tatatgctca ggtttgggca tgatgttttt tatgcttgcg
    19201 ggttgtacaa ccaactatgt gatgacgacg aagaatgggc aaacgatcgt aactcagggt
    19261 aagccgcagt tagataaaga gacgggaatg accagttata ccgatcagga aggcaaccag
    19321 cgggaaatta acagcaatga tgtggcgcag ttgattaagg ctgactaagc attgggcgcg
    19381 atgcggtgtt ggcggcaacg cgcattaaac ccggcaggcc tgaggctgcc ggggaagggt
    19441 aatgttatgt cgctgcttct tctttcaata cgacactctc tgtcgaatcc gccgtcactg
    19501 gcgcagtgcg atggatctcc gccacgcgac gtcgcacgcc aaaccagccg gcgaccagca
    19561 gaatagcgat cagcggcaac gaggcgatag tgtaagttcc attcgggtag tcaaacgcca
    19621 tgagtaccag cacgcttaat aaaaacagca gcgttaacca ggaggtgaaa ggcgcgccgg
    19681 gcagtttaaa actgacgtct gcggctttgc cttcttttat cgcctggcgt aaacgcatct
    19741 ggcacaccat gataaacgcc cacgacgcga taatgccgag cgaggcaaaa ttaagaacga
    19801 tctcaaacac gcgggagggg accagataat taaggaacac gccgaccacg taaaccacca
    19861 gagtcgccag aatacccgca tagggcacat gctgacggct cattttcgcc atgaatttcg
    19921 gcgcggaccc ccccatcgac attgaacgta aaattctccc cgtacagtaa agcccggagt
    19981 tcaggctgga aagcgcggcg gttaacacca cgatattcat aatactgccg atataaggca
    20041 cgccaagttt agaaaagaag gtgacaaacg gactttgccc cgcctggtag gcgttccacg
    20101 gcagcagcaa aaccagcaat acgaccgatc ctacatagaa aagaccaata cgccagatca
    20161 cgctattgat ggcttttggc accatcgtct gtggatcttt gcactcccca gcggcggtac
    20221 cgaccaattc aatcgaagca aaagcgaaca ccacgccctg aatcagtacc agcgcgggca
    20281 acaggccgtg cgggaaaaag ccgccattat ctgtaatcag gtgaaaaccg gtggcattac
    20341 cctcaagcgg ttgaccggta ccgagaaaaa tcgtgcctac caccaggaag ataacaatgg
    20401 cgagtacttt tatcagcgcg aaccagaact ccatttcggc aaaccatttt acgccgatca
    20461 tgttcatggt accgacaatg gttaacgcgc cgagcgcaaa cacccattgc ggaacgtcgc
    20521 caaatgcgcc ccagtagtgc atgtataacg ccactgcggt gatatcgacg atcccggtca
    20581 tcgcccagtt aataaagtac atccagcctg ctacgtaggc cgctttttca cccaaaaatt
    20641 cacgggcgta ggagacgaag ctcccgctgg aagggcgatg caataccagt tcgcccagcg
    20701 cgcgtaaaat gaaaaaagaa aaaatgccgc atatcagata gaccagcgcc agtgccggtc
    20761 cggccatttg caatcgggcg cctgcaccta aaaataaacc ggtgccaatc gcgccgccga
    20821 tagcaatcat ctgaacctga cgattcccca tcgctttgtg atacccctct tcatgggcgt
    20881 tcagccagcg tcgtttcgcc gcatgttgtt ctgcggcgtg cgtagtctgt gttttcatta
    20941 cgttacctgt tatagcctgt cctgacagaa aaattcctta tgccgcgacg ggcgctcacc
    21001 aatcgattgc ctgcaatggc gaatgccgct tttccctgat tctgtgacag ggataaaacc
    21061 gccggcggag catcctacct gcaattgtta aatgacgcaa aacatacgga aagaacaaaa
    21121 tgaggatgtc gtgtttattt gtgcggtcag atgtggtgcg gtgtggtcac gattcagcca
    21181 gataagcttt cagcacaaat ccgcagtgat tgcgttgcgc aataattaat cagagttaat
    21241 ccctgcaggg atttatggtc atagatatga cctcgaacga taaaccacct gacgatattg
    21301 aagcagcata agatcaggcc gttgcgcctg ttattctcat tttctcctga aaatgtatgc
    21361 ctttgagcaa ttttgttgat tgacatatcg tcataatgag agaggagtag gacatataaa
    21421 gctattgagc aaaatttgaa ggagcaggat atgccatata catcagtttc tacctatgcc
    21481 agagctttat caggaaataa gctacctcat gttgctgcag gagattatga aaataaatta
    21541 tcaacaaaaa tcatgaaagg catcttgtat gtgcttaccg caggactggc ctacggattt
    21601 acgcgagtaa ttgaacatta ttgcaatgtt acgcctaaag ttgatgagtt ctgtgccaat
    21661 gcagggaata tccataatca ccttgcagat gctgtacgtg atgaacaatt tattatagat
    21721 gtcgagcttt ctgatggtcg gatgttaaca ttcgaacaac tctcgctgat ggctggacgt
    21781 gagccaatcg tcaggatatc ggatggcgaa catagcgttg aggttaaggg gtcctttgaa
    21841 gatatctgta tgagactgga agagggcttt tttgaagcgc cagcatacta tggttatgat
    21901 attgatgaaa aatataaaac cgtcagagag cgaatagcag catataatgc cttacctcag
    21961 gcattaggcg ccattccgag tttaaaatat tataccgatc gggccaacga catgccggag
    22021 gcgaaagcgc aacgggcggc cgacataaaa gatcgttacc ataactattt agacaagtat
    22081 taaaaagcgt ttatgtttag ccagttttgt tagaaatcag actcgctgag ctggcgttaa
    22141 aaattttaac acgccgctat tttggcggcg tgtcgcaaag agattctcag aacccgattt
    22201 ccgtttatac gccaaaattc tacgtacccc ggcggctgta gccggcctgt cttatttttt
    22261 caaaagtatc caacgctatt ccacggatag ggtatcctgt tgcgcagcga tatccacctc
    22321 agcctgtgtg ccgaacgcaa gcattaatgt taatggaagc ctcagatgac ctctttttta
    22381 catgcttatt ttacgcgatt aaattgtcag ccgttggggg gtcctacggt tgaagcgctc
    22441 agaacgcttc acttagcgca caactgcgcg attccttttg aaaatctgga tgtgctactg
    22501 cctcgtgaaa tacagcttga tgagacggca ctagaggaga aactgcttta tgcccgacgc
    22561 ggtggatact gttttgaact gaatggcctg tttgaacgcg cgttacgcga catcggtttt
    22621 aacgtccgaa gcttattggg gcgggtcatt ctgtctcatc ccgccagttt accgccgcgc
    22681 acgcaccgtt tgctgctggt tgatgttgag gatgagcagt ggatcgcgga cgtggggttt
    22741 ggcggccaaa cgctaaccgc accgcttcgt ctgcaggctg aaattgccca gcaaacgccg
    22801 catggcgaat accgcctgat acaggagggg agcacatgga ttttacaatt ccgccaccat
    22861 gagcactggc agtcgatgta ctgttttgat ctgggggtgc agcagcagag cgatcatgta
    22921 atgggcaatt tctggtcggc tcactggccg caatcccatt ttcgtcatca tttgttgatg
    22981 tgccgccatt tgcctgatgg cggcaagctg acattaacga atttccactt cacgcgttac
    23041 caccagggac atgccgttga acaggtcaat ataccggatg taccgtcgtt gtatcagtta
    23101 cttcagcagc agtttggtct cggcgtaaat gatgtaaagc acggttttac cgaggcggag
    23161 ctggccgcgg taatggctgc atttgatacc catccggagg cgggaaaata attttttgcc
    23221 gcgaggattt gcgggcctga caaagattaa aaagtaatgg cccattcggc atgaaacaga
    23281 atgaccgcct ggccggagat ggtgacgttt tccggctggt tatcgcgaat ggtgacggta
    23341 acatcaacag taccctcttt gcctaaagcg cgcccctgat ggccttgaat ctgtagcgtt
    23401 ttaccgtcat gcgccatcag gccatgatgg acgagccatg cccccatcgg gccattggcg
    23461 tttcccgtta ccggatcttc cacaattcct atcgccgggg aaaacattcg cccatcggtt
    23521 tcgttttttc ccggacgaat ctggaaagga aaaaagccgt tacagccaat ttgctggctg
    23581 attgccgtca gggctgccag attcggcgaa agggcatcaa tatcaacgtc tggtttgagc
    23641 aggatcatca cttttgcatg tcctgttgaa gccacctgaa ttggcgctcc cggcacgata
    23701 tcatcttcag tcaggttcag tgcggtgatg atggcagccc gaatctctcc gactagcggt
    23761 ggttcaaaag agggctgacc ttgttccagc gtgatgcgat agtcgttgtg ttcggcatga
    23821 atttcaacgc gatgacggcc cgctaacgag gtttgccaga cggtggtgtt tcccaacccc
    23881 agtaccgttg cccgaacata atgcgcggcc acagtggcat gaccacagat ggggacttct
    23941 actgtcggtg taaagtagcg tatgcgcaca tcactctctt cgctttttag caaaaaggcg
    24001 gtttccgagt gacgaagttc acgggcaatc agctgcatct gcgcgtcgct tagcgtatcc
    24061 gcatgtaaga caacgccagc agagttgccg cgaaagggtt cgctggtgaa ggcgtcaaca
    24121 tggtaaatct gcggtttcat tgatgttctc ctttgactga agaatcatca tagcctgtgc
    24181 gttgccgaat gacgacgccc aggcgttttt ctttgcccgg taagcgtacc cccggtcaaa
    24241 gagaattagc ggcgggtacg aacaatctgg tagcgacggg tgaaatactc gaacggcgcg
    24301 ctccagacat gaaccagacg ggtgaacggg aagagcagga aaatagtcat tcccagcacc
    24361 agatgaacgc ggaaaacaaa cgccacaccg ttcagtattt ccgaagaccc gccgcggaag
    24421 gtgacaatac tttgcgccca gcccaccaac ttcatcattt cgctgccatc cggatattgc
    24481 gccgaaaacg gaatggtgct caggccaagc aggcactgaa tcagcaaaat gctcatgatg
    24541 ataatatcag gtgtagtgga tgtcgcccgc acacgctgat tggtcagacg acgccacagt
    24601 aatcccgcgc cgccgatcaa cgttaatacg ccgcacacgc cgccgaggat catcgccatc
    24661 tgctgcttta ccgcaatcgg caggaaccag gcatacatcc agtgtggcgt cagcatccca
    24721 aacagatggc caaagaagat ccccagaatg ccaatatgga acagattcga ccatatcacc
    24781 atcccacgct tgtccagcat ctggctggac gacgcgcgcc aggtatattg tccgtagtca
    24841 tagcgcagcc aactgccgag gaagaatacc gtggcgcaaa tataggggta gatgtcgtaa
    24901 aaaaagacgt tcaggtactg tatcatttcg ggcctcccgc gctgacgtcg acgtactgcg
    24961 gcgccgcgtc ctggctaaag cgtcgttgat aatggtgtaa cggtgaactg tcacaggtcg
    25021 tggcgttatc ttcgataaac ttcacctgtt cttcttccca gacggcgtcc agtgcctgac
    25081 gggtatcatc ccgcgattcc tgaacaatct gcttggtgac actgtcactt gtaagcgtac
    25141 tgcccgccag cgtcagcagg gcgtcaaata gttgatacca cggcgctcct cgctgtttca
    25201 gacgaccgcc cagtagcgcc agaatagggg caatattctg taatccctcg cgcgcttccg
    25261 cttccggcaa cacgcttaag tactccagat agagcggcag gtgatccggc agttcgcggc
    25321 agttgaggtg caggcccacg gtttcatact ggcttaacaa atcgaccatc gcctggccgc
    25381 gatcgcggga ctccgcatga acatgctcga ataacagcaa tgaagtggcg cgcccgcggt
    25441 caaacacttc gcaccattct gcttgtttat ccagtaacgg cgcataaagc agctcgcgag
    25501 tgaagttggc cagcattggc gcatcgtgtt ggattagggc aagcgcttca tcccgacatt
    25561 cccacaactc gtcgtccgga tactccatca acaggccaat cgctttgagg atttgcatta
    25621 ttccccctcc gctttatcac gtacttcggt gatattgatg gcatcaatac ggctactgtt
    25681 gaacaggttg aatttggtat ccgagccgtg acaaccgtcg ccaaaagtaa agccgcagcc
    25741 gttgcgctcc ggaaaggcat cgcgcgccat ttcccggtgg ctggtgggaa tgacaaaacg
    25801 atcttcataa ttggcaatcg ccaggtagcg atacatctct tcaacctgtt gtacgctcag
    25861 accgacttcg tcaatggcgc gggtatccgt cacgccttca accgtctgcg agcgcatgta
    25921 gtggcgcatc gccatcatcc gctttagcgc ccgaatgacc gggccggtat cgcccgcgct
    25981 gagcatattg gccaggtact ggaccggaat acgcagcgtc tccaccgccg gcagaatatt
    26041 gccattgtgc ggcaacccgc ccgcgtcggc gtatgactgg atgggcgata gcggcggtac
    26101 gtaccagacc atcggcaggg tacggtattc cgggtgcagc ggaagcgcca gcttccagtc
    26161 catcgccatt ttgtacaccg gcgaccgttg ggcggcgtcg atgacgtttt gcgggatgcc
    26221 ctgtttaagc gcctcttcga tgaccgccgg atcgtgcgga ttgagaaaca catcgcactg
    26281 acgttcatac aaatctgtct cgtgttcggt actggccgct tcttcaatcc tgtcggcgtc
    26341 gtagagcaga acgccaagat aacggatgcg cccgacgcag gtttccgagc aaacggtcgg
    26401 ctggccggat tcaatacgcg gatagcaaaa tatgcatttc tcagacttgc cgctcttcca
    26461 gttaaagtag atttttttgt atgggcagcc gctgatacac aaacgccagc cccggcattt
    26521 atcctggtcg attagcacga tgccgtcttc ttcacgctta taaatagcgc cacttgggca
    26581 ggtggcaaca caactggggt tcaggcagtg ttcgcacagg cgcggcaggt acatcatgaa
    26641 ggtgttttcg aactgaccgt acatctcctt ttgtatgttg tcgaagttgc ggtcgcgggc
    26701 gcgtttttca aactcgccgc cgagcagctc ttcccagttt ggcccccaga tcaccttgtc
    26761 catccgtttt ccgtcgatca gtgaacgcgg acgggcagtg ggctgatgct tactctccgg
    26821 cgctgtatgt aaatgctgat aatcgaaggt aaagggttca tagtaatcat cgatttgcgg
    26881 aatcaccggg ttggcgaaaa ttttgctaat tacccccatt ttgccgccca gacggggcct
    26941 tatcttgcca ttaacatcac gaacccaacc gccttgccac tcctgctggt cttcccaatt
    27001 tttgggatag ccaatacccg gtttagtttc gacgttattg aaccatgcgt attccatccc
    27061 ttcacgtccg gtccagacgt ttttacaggt gacggagcag gtgtgacagc caatacattt
    27121 atcgagattc agtaccatcc caacctgtga gcgtattttc attttttcgc ctcctgtacc
    27181 tgatcccggc cctcatcatc cagccagtta atgtttttca tcttcctgat catgatgaat
    27241 tcatcgcgat tcgaacccac ggttccgtaa tagttgaagc cgtaagccag ttgcgcatag
    27301 ccgccgatca tatgcgtcgg ttttggacag acccgggtca cggagttatg gatcccgccg
    27361 cgcatcccgg tgacttccga acccggaatg ttcataatcc gctcctgggc gtggtacatc
    27421 atggtcatac ccggcgggac gcgctggctg accaccgcgc gagcggtaag ggcgccatta
    27481 gcgttgaagg cttcaatcca gtcgttatct tcaataccca gttcacgggc atcggcttcg
    27541 ctgatccaga caatcggccc gccgcgcgac aaggtcagca tcagcaggtt ttcgctgtag
    27601 gtggagtgaa ttccccattt ctggtgcggc gtcaggaagt taagcgcttt ttccgggaaa
    27661 ccgttgggcg gaatttctcg catttcgctg acgctgcggg tatcaatcgg cgggcgatat
    27721 gccaccaggc tttcgccaaa agcgcgcatc cacgcatgat cctgatagag ttgttgccgc
    27781 cccgacaacg tgcgccacgg gatcagttca tgtacgttgg tatacccggc gttataagag
    27841 acatgctcgc tttccagtcc tgaccaggtc gggctggaga taattttgcg cggttgcgcc
    27901 tggatatcac gaaagcgaat tttctcatct tctttattga tggccagatg ggtgtgctcg
    27961 cgcccggtca tctcgcccaa cgcctgccag gctttcaccg ccacctggcc gttagtttcc
    28021 ggcgctaagg caagaatcac ttccgaggca tccagcgcgg tgtcgatgcg cggacgtcct
    28081 ttcgccgggc catcgtgttt ggtgtaattg agcttaccga ggaaatcgac ttcatcttgc
    28141 gtattccagg caataccctt accgccgttg cctaatttat ccagcagggg acccagcgag
    28201 gtaaaacgtt cataggtggc cggataatcg cgttcaacca cgacgatatt gggggcggtt
    28261 ttgcccggaa taagttcgca ctcgccttta cgccagtcga gaatatcaaa tggctgcgcc
    28321 agttccgccg gggaatcatg ctggagcggg tgtaacacca catcggtttc ctgtccgagg
    28381 tgtccgacac acacttcaga aaaggcgctg gcgatgcctt tgtagatctc ccagtcgctt
    28441 ttggattccc aggcaggatc gaccgcggcg gaaagggggt ggataaacgg atgcatatcc
    28501 gaggtattca tatcgtcttt ttcataccag gtggcggtcg gcaagacgat atcggaaaac
    28561 agacaggtac tggacatacg gaaatcaagc gtgaccaaca gatcgagctt gccctcaatc
    28621 gcggcggact gccattccac ctcttcaggc ttaattcctt cgctggaacc cagcgcttcg
    28681 ccctggatac cgctgtcggt gcccagcaga tatttgagca tgtactcatg acctttcccg
    28741 gaggagccga gcaggttaga gcgccagaca aataaatttc gcgggtgatt atgaccactg
    28801 tcaggccgtt cgcaggcaaa acggatagcg cctgatttca acacctgcat ggtataatcc
    28861 gccgcagaca gcccggcttt atcggcgctc gctttcacgc tgagcgggtt aagattaagc
    28921 tgcggcgccg agggtagcca gcccatacgt tccgcgcgca cgttgaaatc gatcagatgt
    28981 ccggtaaatt tagtcggatc ggccaacggc gacagcaact cttgcgcagt cagtttttca
    29041 tagcgccact ggctggcatg gttgtagaaa aacgaggtac tgttcatctg acgcggcggg
    29101 cgattccagt ccagcgcgaa ggccagcggc agccagccgg tttgcggccg cagcttctcc
    29161 tggccgacat agtgcgccca gccgccaccg gtttgtccaa cacagccgca gaacaccagc
    29221 atgttaatca tcccacggta attcatatcc atgtgatacc agtgattcac tcccgcgccg
    29281 aggatgatca tcgaacgacc gtgagtttta tgggcggtct cggcaaattc acgcgcaata
    29341 gtttcgatat gtcgacgcgg cacgccggta atctgttcgc cccaggccgg cgtgtaggct
    29401 ttgacatcgt tataattatt ggcgctatgg ccgtcatcca gaccacgatc cagcccataa
    29461 ttagccagca ccagatcgta aacgctgacg accatccgct cgctaccgtc cgccagagcc
    29521 aggcgtttca ccggtaactg acgtaccagc accggttcct gccgcacgct gcgaaaatgt
    29581 gggttttcgt tgtcgccaaa ataggggaag gcgacacccg ccacgtcatc atgctgaccg
    29641 agtaaagaga gcgacagttc agtttcgacg cccgccgcca ccggttccag gttccatttt
    29701 cccttttcgc cccagcgaaa accgatagaa ccgttgggcg cgaccagttc gcccgtactg
    29761 ttgagcgcga cggttttcca ttccggatta ttggcttctc ccagtccatc caccagatcc
    29821 gacgcgcgca tcatacgccc cggtacataa ctgccgtctg cgcgctcatc caacaggact
    29881 aacatcggca tgtcggtata acggcggcaa tagttaagga aatagtcgct gggattatcg
    29941 agatgaaact ctttcaaaat gacgtgaccc atggccatcg ccagcgcgct gtcggtacct
    30001 tgctttggcg ccagccactg atcgcacagt ttagcgactt cggaatagtc cggggtgatg
    30061 gcaattgtct tggtgccttt gtagcgcact tcggtaaaga agtgggcgtc cggggtacgc
    30121 gtttgcggca cgttagagcc ccaggcaata atgtaggctg agttatacca gtcggcggac
    30181 tccggcacgt cagtctgctc gccccaggtc attggcgacg cgggcggaag atcgcaatac
    30241 cagtcataga agctcagaca agtaccgcca agcaatgaca gataacgtgt tccggcggcg
    30301 taagaaacca tcgacatcgc cggaataggt gaaaaacccg ccacacgatc cgggccatag
    30361 gttttgattg tccagacgtt agcggcggca atgagctgat tcagctcttt ccagttcgaa
    30421 cgaataaagc cgccatgtcc gcgcacctgt ttgtaacttt ggcatttttg cgggtcgttc
    30481 attatagatt cccatgccag caccggatcg ctgtggcggg aaagggcctc tcgccacagt
    30541 tctatcagcc gcttacgcac cagagggtat ttcaaacgat tggcgctata gagataccag
    30601 gagtagctgg cgccgcgcgg ttcatggttc ggtaaatcgg gacgtgtgcg cgggtagtcg
    30661 gtttgctggg tttcccacgt caccagacca tttttgacat aaattttcca actacaggag
    30721 cccgtgcagt tgacgccgtg ggttgagcgc acgatcttat caaactgcca gcgctggcga
    30781 taactgtctt cccagtcgcg gttggtatgc atcatctgac catggccgtc agcaaaggta
    30841 tcgccttttt gtttaaagta acgaaagcga tccaacagtt tactcatgac atttctcctg
    30901 cttcgataaa ttttccgcca tcctgtcgat ttggcgttaa accattaccg gatggccgtc
    30961 ctacaagtgc gtatgttgtt attgttgttt aggcttaaga cgcccgtaga ccagccaggt
    31021 cagcaggacg caagcgatgt aaaacagcaa aaagattttc atggcgccca ccggcgagcc
    31081 ggtcaaggcc aaagaggtgc caaacgcttt tggaataaag aagccgccca cagcgccaat
    31141 agcggagata aaaccgagcg cggcggcggt atccgtcacc gcttcgcgct gcgcctgctc
    31201 atcgctcccg ccgcgcagtt tgacgttgta gagcgtgatc tgccggaaga tcaccgcaat
    31261 catctggaag gtagaaccgc tgccgagacc cgctgtcaaa aacaggccca taaaaacaag
    31321 atagaacgcg ctaaagctgc ctgcgccgga gcctggcagc gtgaggaata gcagggcggt
    31381 aaacagcgcc ataaagataa aattaatgag cgtgacgcga acgccgccga atttatcgga
    31441 gatcacgccg cctgccgatc gcgccagcgc gccgataaag gggccaaaga acgccagttg
    31501 cagaatgttt acgtcgggaa attgcgtttt ggcgagcatg gcgaaacctg cggaaaagcc
    31561 gatgaatgac ccgaatgtcg ccaggtacag caggctaagc agccacaggt gcagacgttt
    31621 tagcaccggc aattgcgagg cgacagacgc ttttgaactg ccgatatcgt tcataccaaa
    31681 ccaggcggca agcgtcgcaa cagccagtaa cggcacccag atccaggcgg cgttagtgag
    31741 ggcgagcagg gagccatcag gttgcggcac gccccggacg cctaaaaaag taaatatcgg
    31801 caaaaaaata accagcggcg caatcaactg catcacactg acgccaagat ttcccagtcc
    31861 gtcgttaata cccaacgcgc taccttgtct ggcttttgga aagaaaaaac tgatgttgcc
    31921 catactggac gcgaaatttg cccccgcaaa accgcacaac agagcgatga gtataaatac
    31981 cccgaaaggg gtggcaggat tttgcacggc gaatcccagc caggcgcaag gaataatcaa
    32041 tattacggta cttaatacgg tccatttacg accaccaaac agtggtacca taaaggagta
    32101 gggaacgcgt aatattgcgc cggaaagaga aggtaatgcg gttaataaaa agagttggtc
    32161 ggtcgtaaaa tcaaatccaa ttttattgag gttgacggca acagcgctaa acaacatcca
    32221 gacgcaaaat gcaaggagca aacaacttac tgaaatccat aagtttcttc tggcgatgcc
    32281 tttcccttta ttctcccaga aggctggatt ttcgggtcgc cagtcactca agagataacg
    32341 gttataattc tcgttttgtc gtgtcatttt acccctcaca tgcgcatatc atttgaaaaa
    32401 aaacacaaaa aagagacaga gcgtcacgcg ctcttttgag aacttattga agttttttta
    32461 gaatattgag tgaaagaata gataaaaaac caggccagcg cggcgcgaag aggagatatg
    32521 atgtttctta attgttacta tttgtaaatt aaaagcgatt tttattaaat tatttgtaac
    32581 tttacgcaaa gagttcaagc gtaatcatac gatccagatg gtatttaaac gcgggatcgg
    32641 ccatttccgg aatacccagc acatacatac cgtccagccc gcacaccagt gcgataagcc
    32701 gccaggcgat atccgtggcg ttagcagtaa acgtaaattc tcctgcctgt ttgccctgct
    32761 cgataattgt gaccgtttcc tcatgccaca tctgcatcgt gaggagataa gcatctctga
    32821 tgtgcgggtc ccggtcggcc agaatttgcg cctctcgcca caattttatg taaggctcaa
    32881 agccgccgtc ttcgctaccc aacatagcgt gaagccgtgc acgccaggtg gcgggcggcg
    32941 gaacttgccc ggcatcgagc agggtacgga tcaaatggac aaaggccagc gctttgagct
    33001 cgcccgccga gctgaagtgg tgatgcacct ggccggcggc gacatcggct tctgatgcga
    33061 tccgtcgcac cgtcatggcg gcaaacccct ctgccagcgc cacgcgcatc gccgcttgca
    33121 ggatcacttc gcggcgttca tcccggttaa ggtaactcat attttcccca cattagccaa
    33181 tgcgcgcagt gtaacaaaaa gctggacatt cgttcaactt accgtaggat cctgaaattg
    33241 gacaggtgtc caggtttaag tttttgaagg gagagttatg tttcgtcagt ggttaacgtt
    33301 agtcattatt gtgctggtct atattcctgt cgccattgat gccacggtct tgcatgtcgc
    33361 cgcgccgaca ctgagtatga cactgggggc cagcggcaac gagctgctgt ggatcattga
    33421 tatttattct ttggtcatgg ctggcatggt gttgccgatg ggcgcgcttg gcgatcgtat
    33481 cggttttaaa cgcctgctga tgctgggcgg gacgctcttt ggcctggcat cactggcggc
    33541 ggcgttttcg cataccgcca gttggcttat cgccaccagg gtattactgg ctattggcgc
    33601 ggcgatgatt gtatcggcga cgctggccgg gatacgcgcc accttttgtg aagagaagca
    33661 tcgcaacatg gcgctgggcg tctgggctgc ggtaggttcg ggcggagcgg cgtttgggcc
    33721 gctcatcggc ggcatattat tagagcattt ttactgggga tcggttttcc tgatcaacgt
    33781 gccgattgtg ctggtcgtca tgggcttaac cgcccgctat gttcctcgtc aggcgggccg
    33841 tcgcgatcaa ccgctcaatc ttggccatgc ggtgatgctg attattgcca ttttgctgtt
    33901 ggtctatagc gctaaaaccg cgctgaaagg gaatttgtcg ctgtgggtca tctcgcttac
    33961 cctgcttacc ggcgcgttgc tactgggact ctttatccgc acacagcttg cgacatcgcg
    34021 tccgatgatt gatatgcgac tatttaccca tcgcattatc ctgagcggcg tcgtgatggc
    34081 gatgaccgcg atgatcactc tggtgggttt tgagctgctg atggcgcaag agctacagtt
    34141 tgttcacggg ctatcgcctt atgaggccgg ggtatttatg ctgccggtga tggtcgccag
    34201 tggattcagc gggccgattg cgggcgcgct ggtctcgcgt ctggggttac ggctggtcgc
    34261 gacgggcggc atggcgttaa gcgcgctgag tttttatggt ctggcgatga cggatttcag
    34321 cacccaacaa tggcaggcct gggggctgat ggcgctgctg ggatttagca ccgccagcgc
    34381 attgctggct tccacgtcgg caattatggc cgctgtgccg gcagaaaaag cggcggcggc
    34441 cggcgcgata gaaacgatgg cttatgaact gggcgcggga ctgggcatcg ccattttcgg
    34501 cctgttgtta agccgtagct tctccgcgtc tatccgtctg cctgccgggc ttgaggcgca
    34561 agagattgcc agagcgtcat cttcaatggg agaagccgtg cagttggcga atagcctgcc
    34621 gcccacgcag gggcaggcaa tactggacgc cgccagacac gcctttatct ggtcgcatag
    34681 cgtggcgtta agcagcgccg ggagtatgct tcttttgctg gcggtaggga tgtggttcag
    34741 cctggcaaaa gcccaacgcc gataacataa cgcctgatga gataagcgct taatgcgcta
    34801 gctggcaggg ggagtccatt tcctcaacct ctttaccgct gaggcgtgcg tattgccccg
    34861 tcagtcgcca gaaggcaggc tgggtttcgg tataaatttc cgcagccaga atcagccgac
    34921 ggcgatcaac ttcgttcagt tccagtaagg tccagggaaa aatagcgatc ggtatcggta
    34981 agccgaaacc acagcggaca cccgcagcca gaacagaagt agcgttcgcc gcgcgaagag
    35041 gatgaaaagt atggcggttc cggggaaagg ggggctagct gtggttgccc gcaggcttcc
    35101 agatacatgg ctattccacc cgaccatttt tgacacagcg tacaatggca ggcatagaca
    35161 tccagcattt cgacgtcaac ggtaaaatgg ctttgtccgc aaagacaacg accagtgaac
    35221 gtctgcacgg catactcctt atgaccgagt ctacatcaag agaaaaagcc agccctgaaa
    35281 ggactgatgg tgatgggcgg caatgccgca gaagcgcatc cggtgggttt ccgctgggcg
    35341 atggaagcga aaaataataa cgatgcgacg ctgattgtcg ttgatccacg ctttacgcgt
    35401 acggcgtcgg tggcggatat ctatgcgcca atacgttccg gtacagacat tacctttctg
    35461 tccggcgttt tgctgtacct gatcgaaaat aacaaaatca acgctgaata cgttaagcat
    35521 tacaccaacg ccagcctgct ggtgcgggaa gactttacgt tcgaagacgg tcttttcagc
    35581 ggctatgacg cccaaaagcg tcagtacgat aaatcctcct ggaactacca gttcgatgaa
    35641 aacggctatg ccaaacgtga tgaaacgttg acgcacccac gctgtgtgtg gaatctgctg
    35701 aagcagcacg tttcgcgcta tacgccggac gtcgtggaaa acatctgcgg tacgccgaaa
    35761 gcggacttcc tgaaggtgtg tgaggtgttg gcctctacca gcgcgccgga tcgcactacg
    35821 accttcctgt atgcgctggg ctggacgcaa cataccgtcg gggcgcagaa catccgtact
    35881 atggcgatga tccagttgct gctcggcaat atggggatgg ctggcggcgg tgtgaacgcc
    35941 ttgcgcggcc actctaatat tcagggctta acggatttag gactgctctc caccagcctg
    36001 ccgggctacc tgacgctacc gtcagaaaaa caggccgatc tgcaaactta tctggccgcg
    36061 aataccccca aagcgacgct ggccgatcag gtcaactact gggggaatta tcctaagttc
    36121 ttcgtcagcc tgatgaaatc tttctatggc gatgcggcgc agaaagagaa tgactggggc
    36181 tttgcctggc tgcctaagtg ggatcagtcc tatgatgtga tcaaatattt caacatgatg
    36241 gatagcggga aagttaccgg ctatttctgt cagggcttta acccggtggc gtccttcccg
    36301 gacaaaaaca aagtggtgca aagcttaagc aaactgaagt atctggtcgt tatcgatccg
    36361 ctggtgactg aaacgtcaac gttctggcag aaccacagca aatcgtttaa cgacggaaat
    36421 cgatgaccat acggccacga atttgtccct gttccatctc tttaaaaata acgttgatat
    36481 cttcaagcgg acgtaaagcg acttttggca cgacttttcc ttccgccgcg aactggaagg
    36541 cttcggtcag atcctggcgt gtccccacca acgaaccgac aacctgaatg ccatccagca
    36601 ccaggcgagg gatatcaagg ttcatggctt ctggcggcag cccgactgcc accacgcggc
    36661 ctccggcgcg aacggcatct actgcggaat taaacgccgc cttagcgacc gcggtaacca
    36721 ccgctgcgtg cgcgccaccg gttttttcct gcacaatttt agccgcatct tccgtacgtg
    36781 aattaatggt cagatctgcg cccatttcct cggccagttt cagttgccca tcattgacat
    36841 caatggcgat cactttcgca ttgaaaacgt ttttcgcgta ctgcaaggcc agattaccca
    36901 gaccgcccag accgtagatg gcaatccact ggccaggttt aatatgagaa atcttcaccg
    36961 ctttataggt ggtaacgccc gcgcaggtaa tactacttgc cgccgcagag tccaggcctt
    37021 ccggtacttt caccgcataa tccgcgacga caatacactc ttcggccatg ccgccatcta
    37081 ccgtgtaacc ggcatttttc acgttgcggc ataaggtttc attgcccgta ttgcaatact
    37141 cacagtgtcc gcatccttca taaaaccacg cgacactcgc gcgatcgccg ggtttcagcg
    37201 aggtgacacc aggaccgact tccgccacga cgccaatgcc ttcgtgtccc agaataacgc
    37261 cggttttgtc accgaaatct ccgtttttca cgtgtagatc ggtatggcat acaccgcagc
    37321 actccatttt tagcaaagct tcaccgtggc gaaggggacg cagcgttttc tcagtaacat
    37381 caacctgatg atcttgtgtg acaacagcag ctttcataac cttctccttt tcttaataat
    37441 gaactgcata gcaggtaata gcaggtaagg tgctattacc tctttaggat taatatttct
    37501 gatgagttat gcaaggcggc agaaatacaa tgtaatagtt tagccaggat tatcctgata
    37561 aatcctcgtt caatacataa aggtggctaa tattagtagc ttgacaaata agcagggaaa
    37621 ggaattcagg tgtgtcgaca gactcaccaa aactaaagaa gaaagtgata tccggcggca
    37681 ttcaccgccg ggtacgtatt aaatggaagt ccgacggtag tcgcggtatt ccggtttcca
    37741 gaagttatcg tcaatcgcct gttgcagcgc ttccgcagag gttttcaccg ctacgccttg
    37801 ttgctgcgcc attttgccta cggcaaaagc gatagcgcgc gacacgacct ggatgtcttt
    37861 aagcgctggt aacactaatc cttcgccgtt attcaccagc ggagaatgtt tcgccagcgt
    37921 ctcactggct gacatcagca tttcatcagt aatgcgcgat gcgccggaag cgataacccc
    37981 aagtccgatg ccggggaaaa tataggcgtt attacattgt gcgatcggat aaaccttatc
    38041 tttccagatg accggcgaga atgggctgcc ggttgccacc agcgcgttgc cttccgtcca
    38101 ggcgataatg tcctgtggcg tggcctccac gcgagaggtg ggattagaga gcggcatgac
    38161 gatcgggcga gggcaatgct tatgcatctc gcggatgatc tcttcagtaa agagcccggt
    38221 ctggccggaa accccgatca ggatatccgg cttcacgtta cgcaccacat ccagcagcga
    38281 cagcacgtca ttttcggtat cccagtgctg gagattgtcg catttctgca ccagttttgc
    38341 ctggaacggc aataaattag gcatccggtc cgtcaacagg ccgaagcgat cgaccataaa
    38401 aacgttctgt cgagcggcat cttcgcttaa accttcacgc tgagtctgcg cgatgatctg
    38461 ttcagcaatc ccacatccgg ctgaacccgc gccgaggaaa acgattttct gctcgctaag
    38521 ctgactgccg gcagcgcggc tggcggcgat caacgtaccg acggtcacgg ctgcggtgcc
    38581 ctgaatatca tcgttaaagg agcaaatctc atcacgatag cgcgtcaaca gcggcattgc
    38641 gtttttctgc gcgaaatctt cgaactgtag caggatatct ggccagcgct gcttaacggc
    38701 ctgaataaac tcatcgacaa acgcataata ctcatcgtcg gtaatgcgcg gatgacgcca
    38761 gcccatgtag agcggatcgt tgagtaactg ttgattgttg gtgccgacat ccagcacaac
    38821 gggaagggta taggccggac taatgccgcc gcaggcggtg tataatgaca gcttaccgat
    38881 aggtatcccc attccgccga tgccctgatc gccaagcccc agaatccgct cgccatccgt
    38941 caccacaata actttaatgt tgtggttagg cacattctgc aaaatgtcgt ccatattgtg
    39001 acggttcgga taagagataa atacgccgcg cgcccggcga taaatctcag agaagcgctc
    39061 acaggccgcg cccacggtcg gggtatagat aaccggcatc atctcttcaa gatggttttg
    39121 caccagtcga taaaagagcg tttcgttggt atcctggatg ttacgcaggt aaatatgctt
    39181 atcgatttct gttttaaacc cctgatactg gagccaggcg cgttcggcct gttcttcaat
    39241 cgactcgacg acctccggca gcagtcctga caaattgaag ttgcggcgct cttctacgct
    39301 aaaagcgctg cctttgttta acagggggaa ttccagcaat acagggccag cgtaagggat
    39361 ataaagggaa cgtgctttct tggttgtagt ttccatgttg ctcactcttt ttcgaataac
    39421 tgtccctggc accgtcgttt atcatcatat attgccttcc accagggaac cgaccctgag
    39481 tataaagcat tgtgagacgt taaggtcatt cctataaaca aaaacaccat tgcagatgca
    39541 atggtgttta acgtcatttc aggactgtac gattactttt ggctatcggc gcgacgcttt
    39601 ctgccggttg ggttattcac cacgctgctg gtgtcgcctt cagtaacaac cttacgctgg
    39661 ttggaaattc tgtaatccag tccaagtata tgacgagcct gacggttcga tttcatgtta
    39721 actcctcaat cctgttgcta gttttaagga caaattcgct tacgcgaaag aaacgtaacc
    39781 cctaaggttg ccgatacagc atagcaggtt ttacagagtc gggtgctgcc cgcttaccac
    39841 atagttgatg gtctgctggt agatgtcact gaggatgtca ttgtcggaag cctcaaccca
    39901 tttggtcagc tccattaaaa tatcatcttc agtgacaacg cctaactccg cgcgtaatcc
    39961 ttgttcaatc gcgttgacca gggccggttg tgctgctgag gtatttgctg agtgataagt
    40021 aaacatataa tgcctccgtg aacatgtatt tatttagtac ggctcgcaga aaattaattc
    40081 gtattcagca tggcaaatat ttttgcggct gtggttaaga ttagtcctgg agttatttta
    40141 acgcaaggcg gaactctaat tgtttacccc agaagaaaat atattatgtt tgccaattac
    40201 atat
//
LOCUS       DAJVKX010000031        40093 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000031 DAJVKX010000000
VERSION     DAJVKX010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 40093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40093
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.031"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(9..362)
                     /locus_tag="OPY25_001583"
     CDS             complement(9..362)
                     /locus_tag="OPY25_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927223.1"
                     /translation="MADAFILLGIVMAMVSLGFILINKLFCFISAGCLLSLCASMASL
                     QLWDASYWGRWGKVCPGLDVIISCDNYHSLYDLGWGLYGIAFLFFTALMLTCVVIILI
                     NMIMALERYCAGWRR"
     gene            complement(470..3016)
                     /gene="cyaA"
                     /locus_tag="OPY25_001584"
     CDS             complement(470..3016)
                     /gene="cyaA"
                     /locus_tag="OPY25_001584"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HCS0927224.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPSGICFYTPDETQRHYLNELELYRGMTPQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDGEERQLLQRKCSLLESWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWSMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDPTRLDLVRRCFYLKVC
                     EKLSRERACVGWRREVLSQLVSEWGWDDARLTMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIHVPPGRANRSGWYLYNRAPNMDSIISHQPLEYNRYLNKLVAWAWFNGLLTSRTHLF
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNKVVHFDFRKLDVFSFGEEQNCLIGSIDLLYRNSWNEVRTLHFNGEQAMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNQVKLPSVVDGFASEG
                     IIQFFFEETGDEKGFNIYILDESNRAEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKTDGRAQVIPFRTQPINTVPPANQDHDAPLLQQYFS"
     gene            3393..4334
                     /gene="hemC"
                     /locus_tag="OPY25_001585"
     CDS             3393..4334
                     /gene="hemC"
                     /locus_tag="OPY25_001585"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HCS0927225.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICERE
                     DPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLD
                     NGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAP
                     LNHSQTALRVTAERAMNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGER
                     RGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA"
     gene            4331..5071
                     /gene="hemD"
                     /locus_tag="OPY25_001586"
     CDS             4331..5071
                     /gene="hemD"
                     /locus_tag="OPY25_001586"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HCS0927226.1"
                     /translation="MSILITRPSPAGEALVSRLRALGQVAWSFPLIEFVAGRELPTLA
                     DRLATLTENDLVFALSQHSVAFAHAQLQRDGRNWPASPRYFSIGRTTALALHTVSGFD
                     IRYPLDREISEALLQLPELQNIAGKRALILRGNGGRELLGETLTVRGAEVSFCECYQR
                     CAKHYDGAEEAMRWHTRGVTTLVVTSGEMLQRLWSLTPQWYREHWLLRCRLLVVSERL
                     AHLARELGWQDIKVADNADNDALLRALQ"
     gene            5093..6262
                     /gene="hemX"
                     /locus_tag="OPY25_001587"
     CDS             5093..6262
                     /gene="hemX"
                     /locus_tag="OPY25_001587"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HCS0927227.1"
                     /translation="MTEQEKSSAVVDETRETVETTPQPVNTEKKSKNGAALVLSAVAI
                     AIALAAGIGLYGWGKQQATAQTETSDALATQLTALQKAQESQKAELEGIIKKQAAQLD
                     DANRQQAALAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITARRAITDDIASLSSVAQIDYDGIILKLNQLSNQIDNLRL
                     ADNDTDGSPMDSDSSELSSSLSEWRVNLQKSWQNFMDSFITIRRRDDTAVPLLAPNQD
                     VYLRENIRSRLLVAAQAVPRHQEETYRQALDNVSTWVRAYYDTDDAATKAFLEEVDKL
                     SQQNITMDLPETLGSQAILEKLMQTRVRNLLAQPTVSTAAPATQTDAPAAAPQGE"
     gene            6265..7461
                     /gene="hemY"
                     /locus_tag="OPY25_001588"
     CDS             6265..7461
                     /gene="hemY"
                     /locus_tag="OPY25_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HCS0927228.1"
                     /translation="MLKVLLLFVLLLAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILIVAMVVLFAIEWLLRRLFRTGAHTRGWFASRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMSKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTSAWSSLLDIIPSMAKAHV
                     GDEAHRAMLEQQAWIGLMDQARAEQGSEGLRTWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDMAQQIIIDGLKRQYDDRLVLPIPRLRTNNPEQLEKVLRQQIKTVGDRPLLWSTL
                     GQSLMKHGEWQEATLAFRAALKQRPDAYDYAWLADALDRLHQPEEAAAMRRDGLMLTL
                     QNNPPQ"
     gene            complement(8043..8119)
                     /locus_tag="OPY25_001589"
     tRNA            complement(8043..8119)
                     /locus_tag="OPY25_001589"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8083..8085),aa:Pro,seq:tgg)
     gene            complement(8162..8248)
                     /locus_tag="OPY25_001590"
     tRNA            complement(8162..8248)
                     /locus_tag="OPY25_001590"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8212..8214),aa:Leu,seq:cag)
     gene            complement(8269..8344)
                     /locus_tag="OPY25_001591"
     tRNA            complement(8269..8344)
                     /locus_tag="OPY25_001591"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8309..8311),aa:His,seq:gtg)
     gene            complement(8399..8475)
                     /locus_tag="OPY25_001592"
     tRNA            complement(8399..8475)
                     /locus_tag="OPY25_001592"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8439..8441),aa:Arg,seq:ccg)
     gene            complement(8578..9963)
                     /locus_tag="OPY25_001593"
     CDS             complement(8578..9963)
                     /locus_tag="OPY25_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCS0927229.1"
                     /translation="MAEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIIIGLGVIFFGFGNGGQAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAVAKVSRHGVPVA
                     GVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKEA
                     IADHPFRSIMFPWANYLTMAFLVCVLIGMYFNEDTRMSLFVGVIFLLAVTLVYKVFGL
                     NRHGTAHKVGE"
     gene            complement(10170..10910)
                     /gene="rffM"
                     /locus_tag="OPY25_001594"
     CDS             complement(10170..10910)
                     /gene="rffM"
                     /locus_tag="OPY25_001594"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HCS0927230.1"
                     /translation="MTNNAAAPLYSLRGLPLIGWRDMSHALNYLFADGQLKQGTLVAI
                     NAEKLLTAEDNPEVRALIAAAEFKYADGISVVRSIRKKFPQAQVSRVAGADLWEALMA
                     RAGKEGTPVFFVGGKPEVLAQTEAKLRTQWNVNIVGSQDGYFTPEQRQALFARIHASG
                     AKIVTVAMGSPKQELLMRDCREVHPHALYMGVGGTYDVFTGHVKRAPKIWQNLGLEWL
                     YRLLSQPKRITRQMRLLRYLRWHYTGDL"
     gene            complement(10907..12265)
                     /gene="wzyE"
                     /locus_tag="OPY25_001595"
     CDS             complement(10907..12265)
                     /gene="wzyE"
                     /locus_tag="OPY25_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HCS0927231.1"
                     /translation="MSLMQFSGLLVVWLLSTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAACFYGVYYVTYKTRLRKRVVDVPR
                     KPLFTMNRVETHLTWVILMGIALVSVAIFFMHNGFLLFRLHSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGLNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYHNIDFQGLAPIVRDFYVFIPTWLWPGRPSIVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFLVVFGASLLVAKLLFWLFDSAGLIHKRTTSLPQAQMDG
                     KL"
     gene            complement(12262..13341)
                     /locus_tag="OPY25_001596"
     CDS             complement(12262..13341)
                     /locus_tag="OPY25_001596"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HCS0927232.1"
                     /translation="MTVLIHVLGSDIPHHNHTVLRFFNDTLAATGEHAREFMVAGEDN
                     GFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRFFFHGQFNISLWLALLSGGIKPA
                     QFYWHIWGADLYEVSNGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGEL
                     LYFPTRMDPSLNAMAKERQRAGKLTILVGNSGDRSNQHIAALRAVYQQFGDTVNVVVP
                     MGYPANNQAYIDEVRQAGLALFSAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKS
                     GITFFSPNYLQPWHNALRIAAGEAE"
     gene            complement(13338..14588)
                     /gene="wzxE"
                     /locus_tag="OPY25_001597"
     CDS             complement(13338..14588)
                     /gene="wzxE"
                     /locus_tag="OPY25_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HCS0927233.1"
                     /translation="MSLAKASLWTAVSTLVKIGAGLLVVKLLAVSFGPSGVGQAGNFR
                     QMITVLGVLAGAGIFNGVTKLVAQHHDDPAQLRTVVGTSSAMVLGFSTLLALVFLLAA
                     APISQGLFGHTDYQGLVRLVALVQMGIAWANLLLALMKGFRDASGNALSLIVGSFLGV
                     AAWYLCYRVGGYEGALLGLALVPALVVVPAGIILIKRGTVPLRYLKPSWDNGLAGQLS
                     KFTLMALITSVTMPVAYVMMRNQLAAHYSWSDVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKQDITREVVKALKFVLPAVAAASFTVWLLRDFAIWLLFSAKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEISQFILLTAFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(14590..15720)
                     /gene="rffA"
                     /locus_tag="OPY25_001598"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(14590..15720)
                     /gene="rffA"
                     /locus_tag="OPY25_001598"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HCS0927234.1"
                     /translation="MIPFNAPPVVGTELEYMQSAMSSGKLCGDGGFTRRCQQWLEQHF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSFTFVSTANAFVLRGAKIVFVDIRP
                     DTMNIDETLIEAAITDKTRAIVPVHYAGVACEMDVIMALADKYNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDRTLIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLSLWQTYYDALTPLARAGR
                     IELPSIPENCGHNAHMFYIKLRDIADRSALINFLKEAEIMAVFHYIPLHDCPAGDKFG
                     EFIGDDVYTTKESERLLRLPLFYNLAPVDQRTVITTLLNYFS"
     gene            complement(15725..16402)
                     /gene="rffC"
                     /locus_tag="OPY25_001599"
                     /gene_synonym="wecD"
     CDS             complement(15725..16402)
                     /gene="rffC"
                     /locus_tag="OPY25_001599"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HCS0927235.1"
                     /translation="MPVRASIEPLHWENTFFGVNNGIVRIDASAPELTPEALQAWQRV
                     QAKVPAENIAWLSALQSLGFSLVEGEVDFALPVKGHRDQHGAEIAHLTDIPALRQLAG
                     EAFTQSRFRAPWYAPDASARFYAQWIENAVRGTFDHQCLVLRTETGAIRGYVSLRELN
                     DTDVRIGLLAGRGAGAELMQAAICWAQSRGKATLRVATQLGNTAALKRYIQSGANIES
                     TAYWLYR"
     gene            complement(16380..17261)
                     /gene="rfbA"
                     /locus_tag="OPY25_001600"
     CDS             complement(16380..17261)
                     /gene="rfbA"
                     /locus_tag="OPY25_001600"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCS0927236.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPVYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKRDFQRLLGDGAAFGIDLHYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRQVAARTEGATVFGYQVMDPERFGVVEFDDDFRALSLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKRVKPSGRGELEITSINQMYLEEGKLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDDGLKRAASQLEKT
                     GYGQYLLELLRARPRQY"
     gene            complement(17294..18361)
                     /gene="rffG"
                     /locus_tag="OPY25_001601"
     CDS             complement(17294..18361)
                     /gene="rffG"
                     /locus_tag="OPY25_001601"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCS0927237.1"
                     /translation="MKRILVTGGAGFIGSAVVRHIIHETADAVVVVDKLTYAGNLMSL
                     ASVAQSDRFAFEKVDICDRASLEQVFQQYQPDSVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWSALDADAKAAFRFHHISTDEVYGDLHTADDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLVTNCSNNYGPYHFPEKLIPLMILNALAGKPLPVYG
                     NGQQIRDWLYVEDHARALYHVVTNGAVGETYNIGGHNERKNLDVVRTICALLEELAPQ
                     KPQGVANYHDLITFVDDRPGHDLRYAIDASKIARELGWTPQETFESGMRKTVQWYLAN
                     EAWWKPVQDGSYQGERLGLKR"
     gene            complement(18361..19623)
                     /gene="wecC"
                     /locus_tag="OPY25_001602"
     CDS             complement(18361..19623)
                     /gene="wecC"
                     /locus_tag="OPY25_001602"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HCS0927238.1"
                     /translation="MSFTTISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPALGNVVKMAVEGGFLRATTTPVEADAYLIAVPTPFKGDHDPDMAYVEAAA
                     KSIAPVLKKGALVILESTSPVGATEQMAGWLAGMRPDLTFPQQAGEQADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASALYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICAEQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDGKPHWVVDQVKAAVADCLAATDKRASEVKIACFGLAFKPNI
                     DDLRESPAMGIAQSIARWHSGETLVVEPNIRQLPKKLDGLCTLAKLDAALAAADVLVM
                     LVDHDEFKAIPGDAVHQRYVVDTKGVWR"
     gene            complement(19620..20750)
                     /gene="wecB"
                     /locus_tag="OPY25_001603"
     CDS             complement(19620..20750)
                     /gene="wecB"
                     /locus_tag="OPY25_001603"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HCS0927239.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLD
                     QVLTLFSIVPDYDLNIMQPGQGLTEITCRILERLKPILADFKPDVVLVHGDTTTTIAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLREN
                     IPDERIFVTGNTVIDALIWVRDRVLTSDTLQAELAEQYPFLNANKKMILVTGHRRESF
                     GQGFEHICQALAEIAAANQNVQIVYPVHLNPNVSEPVNRILGHVENVVLIEPQDYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRETTERPEAITAGTVRLIGTDSRRIVA
                     EVMRLLHDENEYQTMSRAHNPYGDGQSCARILQALKSYRVSL"
     gene            complement(20806..21852)
                     /gene="wzzE"
                     /locus_tag="OPY25_001604"
     CDS             complement(20806..21852)
                     /gene="wzzE"
                     /locus_tag="OPY25_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HCS0927240.1"
                     /translation="MTQPLPGARAVSAENELDIRGLFRTLWAGKFWIIGIGLLFALIA
                     LAYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIKTDPASSDKPSVMDEAYK
                     EFIMQLASWDTRRDFWLQTDYYKQRMVGNSKADAVMLDELINNIQFTPGDFTRAINDN
                     VRLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTVQMKAQVKRQEEVAKA
                     IYSRRVNSIEQALKIAEQHNISRSATDVPADELPDSELFLLGRPMLQARLENLQAVGP
                     AFDLDYFQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGA
                     LIGAGVALTRRRTI"
     gene            complement(21864..22967)
                     /gene="wecA"
                     /locus_tag="OPY25_001605"
     CDS             complement(21864..22967)
                     /gene="wecA"
                     /locus_tag="OPY25_001605"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HCS0927241.1"
                     /translation="MKLLTALSELISIFLFTTIFIFLARKVAIKIGLVDKPNFRKRHQ
                     GVIPLVGGISVFAGICFMFGLSDYYIPHLSLYLICAGVLVFVGAMDDRFDISVKIRAV
                     VQAVIAVVMMVIAKLHLGSLGYIFGPWELVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSSVSFAAMGLILWFDGQTSLAMWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWLLLETTQGKTHSISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLVMRAGFTSRQAFVLITLAAAILAGVGVTAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRQRKNRPNLTK"
     gene            complement(23197..24456)
                     /gene="rho"
                     /locus_tag="OPY25_001606"
     CDS             complement(23197..24456)
                     /gene="rho"
                     /locus_tag="OPY25_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCS0927242.1"
                     /translation="MNLTELKNTPVSELITLGESMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNYDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(24544..24678)
                     /locus_tag="OPY25_001607"
     CDS             complement(24544..24678)
                     /locus_tag="OPY25_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide"
                     /protein_id="HCS0927243.1"
                     /translation="MWFYPSLPVFSRTRSGKIPGSSLIPSCRFSSAYFPVTRQRTDMS
                     "
     gene            complement(24875..25204)
                     /gene="trxA"
                     /locus_tag="OPY25_001608"
     CDS             complement(24875..25204)
                     /gene="trxA"
                     /locus_tag="OPY25_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HCS0927244.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            25348..26613
                     /gene="rhlB"
                     /locus_tag="OPY25_001609"
     CDS             25348..26613
                     /gene="rhlB"
                     /locus_tag="OPY25_001609"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HCS0927245.1"
                     /translation="MSKTHLTEQKFSDFALHPQVVEALEKKGFYNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEY
                     VEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMND
                     LPKPLRLTRSRPGNGPRRAGAPRNRRRSG"
     gene            26732..28213
                     /gene="gppA"
                     /locus_tag="OPY25_001610"
     CDS             26732..28213
                     /gene="gppA"
                     /locus_tag="OPY25_001610"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HCS0927246.1"
                     /translation="MNSTSLYAAIDLGSNSFHMLVVREAAGSIQTLTRIKRKVRLAAG
                     LNNDNHLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTI
                     LGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLS
                     MGCVTWLERYFSDRNLAQENFDDAEKAARDVLRPVADELRFHGWKVCVGASGTVQALQ
                     EIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFT
                     ELNIQSMTLAGGALREGLVYGMLHLAVDQDIRSRTLRNIQRRFIVDTDQANRVAKLAD
                     NFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQ
                     KKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITL
                     QALNENLTLTLPGDWLAHHPLGKELIDQESQWQSYVHWPLDVR"
     gene            complement(28253..30277)
                     /gene="rep"
                     /locus_tag="OPY25_001611"
     CDS             complement(28253..30277)
                     /gene="rep"
                     /locus_tag="OPY25_001611"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HCS0927247.1"
                     /translation="MRLNPGQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     SNFSLFDDTDQVALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAGAKGER
                     DRIFAHCYGLYDAHMKACNVLDFDDLILLPTLLLQRNDEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGQRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQKLTGRGY
                     DSLTRFTHWLGEIQRLAEREPVAAVRDLIHGIDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGNELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFL
                     YVYMVGMEEGFLPHQSSIDEDNIEEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRAKS"
     gene            complement(30377..31105)
                     /locus_tag="OPY25_001612"
     CDS             complement(30377..31105)
                     /locus_tag="OPY25_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HCS0927248.1"
                     /translation="MDFFSINNVMVNIPLGEGGYALSWIEAIGTVFGLLCIWCASREK
                     IINYLFGLINVTLFAAIFFQIQLYASLLLQVFFFAANIYGWYAWSRQNDAREAALKVR
                     WLSCQQTWRLGGICIISILLMTWFIDPVFAMLTRVMLALLQTVGMQVAMPELQPDAFP
                     FWDSTMLVLSIAAMVLMTRKYVENWLLWVIIDVISVVIYAVQGVYAMSLEYVLLTVIA
                     LMGSYSWIKSAQRNGYTSLAARAC"
     gene            complement(31105..31848)
                     /locus_tag="OPY25_001613"
     CDS             complement(31105..31848)
                     /locus_tag="OPY25_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HCS0927249.1"
                     /translation="MQPHIRLNTSMTRAKYALLPGDPGRVDRIARFLDKAEILGQNRE
                     FRAARGWYQGVEIVVLSTGIGGPSTAIAIEELRQVGVNTLIRIGSCGALQDSLALGDV
                     IIAHGAVADDGASKTYAPASYPACADPYLTATLIQQAKQMNISAVCGLVRSHDSFYTD
                     REAELDAEWSARGVLGADMETAALMVVGALRGLRTASLLNVVVAHSGCLESSINHYVQ
                     QETLCQQGEERQISLALQAIYFDSLQGEQ"
     gene            complement(31876..32577)
                     /locus_tag="OPY25_001614"
                     /pseudo
     CDS             complement(31876..32577)
                     /locus_tag="OPY25_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004127355.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
     gene            32771..33052
                     /gene="ppiC"
                     /locus_tag="OPY25_001615"
     CDS             32771..33052
                     /gene="ppiC"
                     /locus_tag="OPY25_001615"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HCS0927250.1"
                     /translation="MAKMAAALHILVKEEKLALDLLEQIKNGGDFEKLAKKHSICPSG
                     KKGGHLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRK"
     gene            complement(33144..34619)
                     /gene="ilvC"
                     /locus_tag="OPY25_001616"
     CDS             complement(33144..34619)
                     /gene="ilvC"
                     /locus_tag="OPY25_001616"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HCS0927251.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     VNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPE
                     GAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            34784..35671
                     /gene="ilvY"
                     /locus_tag="OPY25_001617"
     CDS             34784..35671
                     /gene="ilvY"
                     /locus_tag="OPY25_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HCS0927252.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTLDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSVDKPDWSTVPFIMADQGPVRRRIELWFRRHKISNPQ
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCA
                     QKKRLHEPLIDAFWKILPN"
     gene            complement(35674..36015)
                     /locus_tag="OPY25_001618"
     CDS             complement(35674..36015)
                     /locus_tag="OPY25_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCS0927253.1"
                     /translation="MIAKTDSDFRHVTPSGGNVFADLGFHKQDAEKFYADSLNEIENT
                     LAIKQQLMEEITLWITQNQMKQAEVATVLHISRPRVSDVVNKKCSKFTIDALVNMLSR
                     IGKPVRVMVGP"
     gene            complement(36012..36329)
                     /locus_tag="OPY25_001619"
     CDS             complement(36012..36329)
                     /locus_tag="OPY25_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCS0927254.1"
                     /translation="MGSSLEDLLAFPITVRKAVGYQLHKIQYGIEPDDWKPFSEIGAG
                     VNEIRIRNNNGIYRVMYVANFAEALYVLHSFQKQTQQTSQHDKNIARTRYNRVVQQRR
                     NSL"
     gene            complement(36610..38154)
                     /gene="ilvA"
                     /locus_tag="OPY25_001620"
     CDS             complement(36610..38154)
                     /gene="ilvA"
                     /locus_tag="OPY25_001620"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HCS0927255.1"
                     /translation="MAESQPLSVAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKSLIVMPKATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELAQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDSHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALEAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIAQHNIRGERLAHVLSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRMVTEFNYRFADAKHACIFVGVRVSQGLEER
                     KEIITQLCDGGYSVVDLSDDEMAKLHVRYMVGGRPSKPLQERLYSFEFPESPGALLKF
                     LHTLGTHWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLHELGYECHDESNNPAF
                     RFFLAG"
     gene            complement(38157..40007)
                     /gene="ilvD"
                     /locus_tag="OPY25_001621"
     CDS             complement(38157..40007)
                     /gene="ilvD"
                     /locus_tag="OPY25_001621"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HCS0927256.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDSDFGKPIITVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLIEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQDDESALPRNIANKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLG
                     ILGELDRAGLLNRNVKNVLGLTLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFS
                     QDCRWDSLDDDRAAGCIRSLEYAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PVKVYESQDDAVEAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGTIALIEDGDTIAIDIPNRSIQLQLSEAEIA
                     ARREAQEARGDKAWTPKNRQRQVSFALRAYASLATSADKGAVRDKSKLGG"
BASE COUNT         9716 a        11207 c        10344 g         8826 t
ORIGIN      
        1 aaggcgcgtt agcgccgcca tccggcacag tatcgctcta aagccataat catattgata
       61 agaataatga ccacacatgt gagcattaac gcggtaaaaa acaaaaaggc gataccgtac
      121 aatccccatc ccaggtcata gagagaatgg taattgtcgc aggagatgat cacatccagg
      181 ccggggcata cttttcccca tcgcccccag taagacgcat cccagagttg caaactggcc
      241 atgctggcgc atagcgagag caggcaccca gcggatataa aacagaataa cttatttata
      301 agaatgaagc cgaggctgac catcgccatg actatcccta acaaaatgaa cgcatctgcc
      361 acctcaaacc tcctcctgta aaccaaatgc ggaggtcacg gtaacgaagt tgggtgaagt
      421 taatgtgaag cggtgaacgc cggccgggca gcgttgcccg gcgcagcact tacgaaaaat
      481 actgctgcaa tagcggcgcg tcatgatcct ggtttgctgg cggcacggtg ttgataggct
      541 gcgtacggaa tgggatcacc tgcgcgcggc catcggtttt cactatctgg tagaactgcg
      601 gcaggttgaa gttgataaag ctggagccat acgtgaagcg atcgtgcgat gacgaataga
      661 agcgactgac gtcgcgcacc agttcttcct tgctaccctc gcagtggtga tacacttccg
      721 cccggttact ttcatccaga atataaatat taaagccttt ctcatcgccc gtttcttcaa
      781 agaagaactg gataatccct tcgctggcga agccatccac cactgacggc aatttcacct
      841 ggttggtttc cacctgtacc gacagcccgt gcagcttgtt atgcgaaatc gcgccgtaga
      901 attcgatagc gttctccagc ttctgcaccg agacattcaa gcgttcgaag aatagtcccc
      961 acgtctgccc ggaaacccgc agcgccttga agcgaccggt ctcctgacgg gtgctggaaa
     1021 gacgtagctc gatacattcg gagaccagtt gctgcacgcg ggtgcgaatc agaccgcgaa
     1081 gatgctgact gtaacagaac acctccacgc tatccggcgg cgcggcatcc tggtgcattt
     1141 tccccagaat cgttttcagc gcttcgatca tcgcctgctc gccgttaaag tgcagagtac
     1201 gcacttcgtt ccacgagttg cgatataaca agtcgatact gcctatcaga cagttttgct
     1261 cttcgccaaa gctgaaaacg tccagcttac ggaagtcaaa atgaaccact ttattgcgaa
     1321 acgccgccgt cgggtcatat tcgaggttaa cgataatcgc cagatggcga atttcacagg
     1381 ggctgtagag cgctttcggc gttggagcag gcaagcgcag cgggaaatgg tgcgaaacat
     1441 cggcgaccat ctcctgcaac ttaggcaggt cgacaatacc gttgccctta ataaacagat
     1501 gcgttcgcga cgtcagcagg ccgttgaacc acgcccacgc gaccagctta ttaagataac
     1561 ggttatattc cagcggctga tggctgatga tggaatccat gttcggcgcg cggttgtaga
     1621 gataccagcc tgaacggttg gcacgtcccg gcggcacatg gataaaggtt aaattcggct
     1681 cggacagatc cggcgatatc tgcgggttca ccagcgtgac tttacccggc aacgcttcaa
     1741 acgccgcgta cagcttacgc gtcagtacgc cgatatcctg cgggctggca ctcacgctga
     1801 ggttgttgcg ccgcgcaaag cgaatcagat tacgatagct ttgcatcatt gcgtcgagca
     1861 attcgttgtg ggcttcgcgc acctgatcga ttttccagtt tgcgcgatta tcgagcatgg
     1921 tcagacgcgc gtcgtcccat ccccactcgc tgaccaactg gcttaatact tcccgacgcc
     1981 agcctacgca ggcgcgctcg cgacttaatt tctcgcacac tttcaggtaa aagcagcggc
     2041 ggactaaatc cagccgcgtc ggatcttcaa tcgccgtcag gtattcagtg acccgttcca
     2101 gcatcatgca gtagggatcg agtccaaacg atacgatttc accgtcatgc agacgttgtt
     2161 taatatcttt cgccagcaga cgtgggttgg ggtattccca tgaataggct tccagcaaca
     2221 gcgttttcag caccgctttg tacggcgagt caatgctctt gtatagctgc cacaggctgg
     2281 cgccaaagta ctcttcggcg gagagcgagc ttaagccccc caaatccagc cattcgtttg
     2341 gcgttaatac gccctgcgcg tagagcgtca tgacatagtc gtcgtaatgc tcttcttcgt
     2401 cgcacggcac catactccac aggatacgct tcccggccag gcgcacagcg gtacgataaa
     2461 actcatcaag caacaggata tgctgcgtag aaccacagtc ttccccgccc agactgccgc
     2521 tttcgttatg gcggaaacgg ttctcgtcaa tcaggaagaa gctcacctca acgccaagcg
     2581 aggcggccca gctttccagc aggctacact tacgttgcag caactgacgc tcttcgccgt
     2641 cgagccagga ctgatggcac acccagatat ccaggtcgga cgagcagctc tgcccgaccg
     2701 aggaggtgct gcccatggtg taaacgccgg taatcggcaa ctcgcccttc ggcggatcct
     2761 gcggcgtcat accgcggtac agctcaagtt cgttcagata gtggcgttgg gtttcatcag
     2821 gcgtgtagaa gcaaataccg ctgggaacgt taccatcaag gtaacccggc atcagtggat
     2881 ggtgatagtg caataatgtc ggcagaagac tgtaaacctg ctgaaaagcg ggtcccatgg
     2941 cagcaagcgc gcgatccaca cgcagttgat ttatggcatc cagtctctgt ttcagagtct
     3001 caatatagag gtacaagacg tatcgcctga tgttgctacc cgtcatggtg caggtcaata
     3061 cttcaccgtc gccattcggg ataaaccgta tgtcaaaaat aaccgttacc ctttctcgcc
     3121 tgcatatttt tatctaatac cgacgaaaaa atggtctaaa acgtgatcaa tttaacacct
     3181 tgctcattga ccgtaaagaa agatgcgcta catacaagtg tagcaccgtt cgctgcgtgt
     3241 aaattcttaa atacgggctg gcggtttctc gtcattattc actgtcattg acgacactgc
     3301 gccttatcct ctcactcacg gtgaccggaa aactaacata ctctctataa ggatgttagg
     3361 atggtcaatg attgataatg acggtaacaa gcatgttaga caatgtttta agaattgcca
     3421 cacgccaaag tccccttgcg ctttggcagg cacattatgt caaagacgca ttgatggcaa
     3481 cccatccggg actgacggta gaactggtgc cgatggtcac acgcggcgac gtgattctcg
     3541 atactcccct ggcgaaagtg ggcggtaagg gactgtttgt taaagagctt gaaatcgcgc
     3601 tgctggaaaa acgcgctgat atcgccgtgc actctatgaa agacgttccg gtggccttcc
     3661 cggacggtct cggtctggtg accatttgcg agcgcgaaga tccgcgcgac gcgtttgtct
     3721 cgaataaata tcacagtctg gacgatctgc ccgcgggtag tatcgtcggg acgtccagtt
     3781 tgcgtcgtca gtgtcaactg gcggaacgcc gtccggatct cattatccgt tcgttgcgcg
     3841 gcaacgtcgg cacacgtctc ggcaagctgg ataacggcga ctatgacgcc attatcctgg
     3901 ccgtggccgg tctgaaacgc ttaggtctgg agtcgcgcat tcgcacagcc ttgccgcctg
     3961 acgtttcgct tcctgccgta ggccagggcg ctgtcgggat tgagtgtcgt cttgacgacg
     4021 cgcgaacaca ggcgctgctc gcaccgttga atcactcgca aaccgcgctg cgcgtaacgg
     4081 cggaacgtgc tatgaacacc cgcctggaag gcggttgtca ggtgccgatt ggcagctatg
     4141 cagaaatcat caacggtgaa atttggctac gcgcgctggt tggcgcgccg gacggttcgg
     4201 tgatggtgcg cggcgaacgt cgtggttctc ccgagcaggc ggagcaaatg ggcatctcgc
     4261 ttgcagagga actgctggaa aacggcgcgc gcgcgattct gacggaagtt tataacggcg
     4321 agacgcccgc atgagtattc tgatcacccg cccctctccc gcaggggaag cgttagtgag
     4381 ccgtctgcgc gcactggggc aggtggcctg gagttttcca ctgattgaat ttgtcgccgg
     4441 tcgggagcta cccaccctgg ccgaccgcct ggcaacgctg acggaaaacg atctggtttt
     4501 tgccctttca cagcactccg tcgcctttgc tcacgcccag ctccagcggg atggacgaaa
     4561 ctggcctgcg tcgccgcgct atttctcgat tggccgcacc acggcgctcg cccttcatac
     4621 cgttagcggg ttcgatattc gttatccatt ggatcgggaa atcagcgaag ccttgctaca
     4681 attacctgaa ttacaaaata ttgcgggcaa acgcgcgctg attttgcgtg gcaatggcgg
     4741 ccgcgaactg ctgggcgaaa ccctgacagt tcgcggagcc gaagtcagtt tttgtgaatg
     4801 ttatcaacga tgtgcgaaac attacgatgg cgcggaagaa gcgatgcgct ggcatactcg
     4861 cggcgtaaca acgcttgttg ttaccagcgg cgagatgttg caacgactct ggtcgctgac
     4921 tccccagtgg tatcgtgagc actggttact acgctgtcgg ctattggtcg tcagtgagcg
     4981 tctggcgcac ctcgcccggg aactgggctg gcaagatatt aaggtcgctg ataacgccga
     5041 caacgatgcg ctgttgcgcg cattacaata actctcataa tgggatgcca taatgacgga
     5101 acaagaaaaa tcctccgccg tggttgatga gaccagggag accgtggaaa ccacgccaca
     5161 gccagttaat accgagaaaa aaagtaagaa cggcgccgcg ctggtattaa gcgcggtggc
     5221 gatcgcgatt gccctggcgg caggtattgg gctttatggc tggggaaaac agcaggcaac
     5281 cgcgcaaacg gaaaccagcg atgcgctggc gacgcaactg accgccttgc aaaaggcgca
     5341 ggagagccaa aaagcggagc tggaagggat tatcaaaaaa caagcggcgc agttagatga
     5401 cgcgaatcgc caacaggcgg cgctggcgaa acagcttgat gaagtacaac aaaaagtcgc
     5461 caccatttcc ggcagcgatg ctaaaacctg gctgctggca caggctgatt tcctggtgaa
     5521 actcgccgga cgcaagctgt ggagtgatca ggacgtcact accgccgctg cgctgctcaa
     5581 aagcgctgac gccagtctgg cggatatgaa tgaccccagc ctgattaccg cacgacgcgc
     5641 gattactgac gatatagcca gcctgtcatc cgttgcgcag atcgactacg acggcattat
     5701 tctcaagctc aatcagctct ctaaccaaat tgataacctg cgtctggcgg ataacgatac
     5761 cgatggttcg ccgatggatt ctgacagcag cgagctgtcc agctcgctaa gcgaatggcg
     5821 cgttaacctg caaaaaagct ggcagaactt tatggacagc tttattacca ttcgccgccg
     5881 cgatgatacc gccgtaccgc tgttggcgcc caaccaggac gtctatttac gcgaaaatat
     5941 tcgctcccgc ctgttagtcg ccgcgcaggc cgtgccacgc catcaggaag aaacataccg
     6001 tcaggcgctg gataacgttt cgacctgggt tcgcgcttat tacgatactg acgacgccgc
     6061 gacaaaagcc ttcctggagg aggtcgataa attaagccag caaaatatca cgatggatct
     6121 gccggaaact ctgggaagcc aggcgattct tgaaaaactg atgcaaaccc gcgtgcgtaa
     6181 tctgctggcg caaccgacag tctctacggc agcgcctgcc acgcagacag acgctccggc
     6241 agccgcgccg caaggagaat aatgatgcta aaagtattat tgctctttgt gttgttgctc
     6301 gcgggtatcg tggtcggccc gatgatagcc ggtcaccagg gctatgtgtt aatccagacc
     6361 gataactaca acattgaaac cagcgtcacc ggcctggcga tcattctcat cgtcgctatg
     6421 gtggtgctat tcgccattga gtggttacta cgccgtctgt ttcgtaccgg cgcgcacacc
     6481 cgcggttggt ttgccagccg taaacgccgt cgcgcccgca agcagaccga acaggcgctg
     6541 ctgaagctgg cggagggcga ctatcagcag gttgaaaagc tgatgtcaaa aaatgccgac
     6601 catgctgaac aaccggtggt aaattatttg ctggcggcag aagcggcgca gcagcgcggc
     6661 gatgaagcac gcgctaatca gcaccttgaa cgtgcggcag agctggcggg gaacgacacc
     6721 atcccggtcg agatcacgcg tgtgcgctta cagctggcgc gcaatgaaaa tcacgcagcg
     6781 cgtcacggcg tggacaaact gctggaggtc acgccgcgtc acccggaagt tctgcgtctg
     6841 gcggagcagg cctatattcg caccagcgca tggagttctt tactggatat catcccatcc
     6901 atggcgaaag cgcacgtcgg cgatgaagcg catcgcgcca tgctcgaaca acaggcgtgg
     6961 ataggactca tggatcaggc gcgtgccgag cagggcagcg aaggattacg cacctggtgg
     7021 aaaaaccaaa gccgtaaaac ccgccatcag gtggcgctgc aggtcgcgat ggccgagcat
     7081 ctaatcgagt gtgacgatca tgatatggcg cagcagatta tcatcgacgg tctgaaacgc
     7141 cagtatgacg atcggctggt gctgcccatt cctcgcctca gaaccaataa tccggaacaa
     7201 ctggagaaag tgctgcgcca gcaaatcaag acggtaggcg atcgcccgct gttatggagc
     7261 acgctcggcc agtcgctaat gaaacacggt gaatggcagg aggcgaccct ggctttccgc
     7321 gccgcgctga aacaacgccc ggacgcgtat gattatgcct ggcttgccga tgcgcttgat
     7381 cgactgcatc aaccggaaga ggccgccgcc atgcggcgcg acggcttgat gctgacatta
     7441 cagaacaatc ccccgcagta attccctctt gcccggtggc gcttcgctta ccgggcttac
     7501 cgcctacaca aaatcattcg ggatgcataa aaaaacgcct gcccggttaa ggggcaggcg
     7561 tcaaaacagg tctgtatgac aacataaagg ggtgcttcac tcaacgttgt gtccagggtg
     7621 tttgatgagg cgtaagcgac atctgtcagt ggacgataag caccgtaaac ggctctgcat
     7681 cattcctgag tttatgaggc cagaaggcga acataagaga tggaatgagc atctacccgt
     7741 acattattgc acataacgtg ccatctttgc accgctaaaa aacaggcgca ggcattaaaa
     7801 aaacgtagag aattcacgcg attgttatcc ccccgccgct ggcgaggttt tagcgtgtcg
     7861 cccggcggag acagaacagg atgcttttta taaagtgatt ataaatcaat agattattcg
     7921 tcaccgaata gcgacaaatg aagtctggga tatcgccaat aaaccataat ggcaacacgt
     7981 gcgggataag gggttgaaaa tgaacagaaa acaaaaaacc ccgccgaagc ggggctcaaa
     8041 attggtcggc gagagaggat tcgaacctcc gacccactgg tcccaaacca gttgcgctac
     8101 caagctgcgc tactcgccga tatactgctt ttttgaattt ttagttcaat tcattgagtc
     8161 gtggtgcgag gggggggact tgaaccccca cgtccgtaag gacactaaca cctgaagcta
     8221 gcgcgtctac caattccgcc accttcgcgt ttcacaactc tatattaatg gggtggctaa
     8281 tgggattcga acccacgaca actggaatca caatccaggg ctctaccaac tgagctatag
     8341 ccaccactga aactttttac gcggtattaa accaccgcag ctcaagcacc taaataaatg
     8401 gtacgcccga caggattcga acctgagacc tctgcctccg gagggcagcg ctctatccag
     8461 ctgagctacg ggcgcttagc gccgttgcgg gggtggataa tacggacttc acaccccgct
     8521 gtccagtgcc tttttaaata aaatgcgcgt ttggttatgc tttgcgcatt ttggcgctta
     8581 ttcccccacc ttgtgggcgg ttccgtgacg attcaggccg aaaactttgt agaccagcgt
     8641 gacggccagc aggaagatga cgccgacaaa cagcgacatg cgcgtatctt cattaaagta
     8701 catgccgatt aaaacgcaaa ccagaaacgc catcgtcaaa tagttcgccc acggaaacat
     8761 aatggaacga aaaggatgat ccgcaatcgc ttctttatgc gcccgacgaa agcgcagttg
     8821 gctaatcaga atgacaaacc acggcaccat ccccggcagt acgctggcgc tataaacgta
     8881 aacaaagacg cgctgcggat tggggataat gtagttcagg caagaaccta ccagcaaaat
     8941 caaaatagag agcgccacgc ccgcgaccgg cacgccgtgg cgagagacct tcgcaactgc
     9001 cgccggcagt tgacggtttt tcgccagcgc gtaaagcata cgcccacagc tatacattcc
     9061 gctgttacag ccggagagcg ccgccgtcag cacgacaaag ttgataatgc ctgccgcggc
     9121 ggtgatgccg attttcgcga aggtgagcac aaaggggctg ccgttgctgc caatctcatt
     9181 ccacgggaaa atggtgacga tcacgaaaat cgcgccaaca taaaaaatca ggatacgcca
     9241 cagcacttta cccaccgcgc tacgcaacgt cacctgcgga ttcttcgctt caccggcggt
     9301 aataccgatc aactcaaccc cttgataaga ggccaccacg atacataatg cggtcagaaa
     9361 gcctttccag ccgccggcaa aaaagccgcc atgctcggtc agattaccaa agccaatcgc
     9421 ctggccgccg ttaccaaagc cgaagaaaat cacccccagg ccgatgatga tcatcacaat
     9481 aatcgtggtg actttgatca tcgcaaacca gaactcgatt tcaccataca ggcgcaccgc
     9541 agccagattc gccaacgcga ccagtccgac ggcaatcagc gccggtatcc actgcgccat
     9601 ctccggaaac cagaactgga cgtagacccc aatggcggta atttccgaga tcccgaccgc
     9661 catccacata aaccagtatg accaggcggt aagatagcca aaaaaaggac tcatataccg
     9721 gtgggcgtac acggcaaagg agccggtaac aggttccaga aagagcatct cccccatcga
     9781 acgcatgatg aaaaagacga acaatccggc gatgatatac gccagcagca ctgacgggcc
     9841 cgcccatttc agcgtactgg cggcgcccat aaagagtccg acgccgatgg tgcccccgag
     9901 ggcaatcaat tcaatatgac gagcttccag cccacgctgt agctccggtt ttttctctgc
     9961 cataaatcct catgtcgtgt ttgcaacggt tccggtagta ccggttattg ttatgggtac
    10021 atcgattgtt gcgaatattt tcttaaattt ggacaaatgg caaatgaagc attaaaaaaa
    10081 tgcgcttatt gtgtaagaaa gcatcgatta tgttgtaaat gagcagagcc ataagcacag
    10141 tccgctgctc aagtcatcag aagggagaat cagagatcgc cagtatagtg ccagcgaaga
    10201 tagcgcagca gacgcatctg gcgggtaata cgcttcggtt gcgaaagcag acgatacaac
    10261 cactccagcc ccaggttctg ccatattttt ggggcgcgtt tgacgtgacc ggtaaacaca
    10321 tcataggtac cgcccacccc catatatagc gcatggggat gcacttcccg acaatcgcgc
    10381 atgagtaatt cctgttttgg cgatcccatc gcgacggtga caattttcgc gccgctggca
    10441 tggatacgcg caaatagcgc ctgacgctgc tccggcgtaa agtaaccgtc ctggctaccc
    10501 acaatattga cgttccactg cgtccgcagt tttgcttccg tctgcgccag cacctcaggc
    10561 ttgccgccga caaaaaatac cggcgtgcct tctttccccg cgcgcgccat taacgcttcc
    10621 caaaggtcgg cgccagccac gcgagaaacc tgcgcctgcg gaaatttttt acgtattgaa
    10681 cgcaccacgc tgatgccatc ggcatattta aattccgccg ctgctatcaa cgcgcggact
    10741 tccggattat cttccgccgt cagcagcttt tcggcgttga tcgccaccaa cgtgccttgc
    10801 ttcagttgac catcggcaaa cagataattc agcgcatgtg acatgtcgcg ccagccaatc
    10861 agaggtaatc cacgcagcga gtaaaggggc gcagcggcat tattggtcat agttttccat
    10921 ccatctgtgc ctgagggagc gaagttgtac gtttatgaat cagtccggcg ctatcaaata
    10981 accagaacag aagtttagcg accagcaggc tggcgccaaa aaccaccagg aagaaaacca
    11041 cgcgcgaaac aaacgaatcc agcccttctc gcgccagcac aatcatatta aagatggcgc
    11101 caaagcagaa actgtgcaga atcgccgcct tatagcgatt gggttcccgg ttacccagtt
    11161 catacagcca gtcgaaccat ttgataatca gcccgacgac gatcgcgccg agcggaataa
    11221 acagtgcccc gcccatgacc accagcgatc cgataagcgt tggcgatatc gccaggccag
    11281 aatggttgtt caggacttcc caggtgaagt aattcgcaga attcagcacg atactgggtc
    11341 gtcccggcca taaccaggta ggaataaaga cgtagaaatc acgcacgata ggggccagcc
    11401 cctgaaaatc gatattgtgg taattttgca acagcagcgc cagattctcc cacggcgaaa
    11461 aggtatcgcg cgtcagataa agaaacgtat agaacgcctc atcgccgctc acatttaatc
    11521 cgtagcgttt gagcgccagc cagaacatac cgacaatccc cagcacgccc gccgctgcca
    11581 gcatccacag gctgatccag ccccgaataa tgccgataaa caggaagata gcaaacgcaa
    11641 taatgatgtt ggcgcgcgtg ccgccgacaa tcatgtaggt caacagacca aacgcgacgg
    11701 tgctcaccag aaagaacagc cacgctttgc tgtcctggcg caggaaatag accaccagca
    11761 tcgccggaat gaagaaatag aagaaccgtt ttaacgccac gccggaaact tcgctggaaa
    11821 agatctggct gtaggagtgt agtcggaaca gcaaaaagcc gttatgcata aagaaaatcg
    11881 ccacgctcac cagcgcgatg cccatcagga tcacccaggt aaggtgggtt tccacccggt
    11941 tcatggtaaa tagcggcttg cgtggtacat ccacaacgcg tttgcgtaaa cgcgttttat
    12001 aggtcacgta atacacgccg tagaaacagg cggcggataa tagagcctgc aataagattt
    12061 ccggcggcgc gacgccaacg tcgaaacgaa ataccagcac gctggttagc ggaaaaccaa
    12121 aaaagaaggt caacaaaaaa agcaacgaaa agaaaacgtt gaagttaaaa cgcacgcggc
    12181 ggaattcaaa ccaagtcagc gtggcgataa acagcgtaga gagcagccag accaccagca
    12241 gcccgctgaa ttgcattaaa ctcattcggc ttctcctgcg gcgattctca acgcattatg
    12301 ccacggttgc aggtagttgg ggctaaagaa ggtgatgccg cttttatcta ccgatgcgag
    12361 ctgacgctgc gcctcgcgca cgacctgctc attaagatcg tccgtggtaa acaggacggg
    12421 cagatgctgt tccgccatat cctgccagaa aggattgtcg cgattcaaca cgcacgggat
    12481 atcggcctga attagcagac acaacgtccc gatcccctgt tggcgggcaa aaataaaata
    12541 accgaggtcg cactggcgca acagcgcaag ataggcatca aattccattt tttcgctaag
    12601 aatttgtaga ttttcggcgc taaatagcgc cagaccggcc tgacgaacct catcaatata
    12661 ggcctggtta ttggctggat agcccatcgg caccaccacg tttaccgtgt cgccaaactg
    12721 ctgatacacc gcccgtaacg ccgcaatatg ttggttactg cgatcgccgg agttccctac
    12781 caaaatggtc aatttccccg cacgttggcg ctcttttgcc atagcattca gagaaggatc
    12841 catgcgcgtc gggaaataga gcaactcgcc gcgtacgccc gggtgctggc gcgcaaaata
    12901 gctgagatcg ccgcgcgtcg cgaatacgcc ccctactcgc ccctgcgcga tacgacgaag
    12961 cgggtagaaa aggcggaatt tcagcccgtt ggacacttcg tagagatccg cgccccagat
    13021 atgccagtaa aactgggctg gcttaatacc gccgcttaac agcgccagcc acagactgat
    13081 gttgaactgc ccgtgaaaga agaatctctg tcgacgattt gctttcgctt tggcgataac
    13141 cgcctgcgcc agcgctttct tactgccata aaaacgaagc gagagtgccg gacagctttc
    13201 cgtgaagccg ttatcttcac cggcaaccat aaattcgcgc gcgtgctcgc ctgtggcggc
    13261 cagcgtatca ttgaaaaacc gcagcacggt gtggttatgg tgagggatat ccgatcccag
    13321 gacgtgaatc agtacagtca tgctcgccta cgccagagta aaaatacgcc gcaacaaagt
    13381 gaaaaataga caatataggt ggccatataa gcctgtgccg cacccagcgc gccgtgagcg
    13441 ggaatcagcc agtgagcgaa cgccgttaac agaatgaact ggctaatttc ggccagaatg
    13501 taaaatcgca acgacgcttt ggcaatcacc agataaccga aaacataggc gccgactttc
    13561 agcacgtcgc ccactaactg ccaagcgaac agatcgcgca tcgcggtgaa tttggcggaa
    13621 aaaagcagcc agatagcaaa atcgcgcaat agccagacgg taaaactcgc cgccgcaacc
    13681 gccggtaaaa caaatttcag cgcttttacc acttcacgcg taatgtcctg tttttccgtc
    13741 aggcgtgaga gcgtaggtaa caggtaaacg ctgaaggagg cggtgataaa ttgtagatag
    13801 gcatcagaaa tactgctcac gccctgccag atcccgacat cgctccagct atagtgcgcg
    13861 gccagttggt ttcgcatcat cacataggcg accggcatcg taacagaggt aatcagcgcc
    13921 atcagggtaa atttactgag ttgccctgcc agaccgttgt cccaggaggg cttgagatag
    13981 cgtagcggga cggtgccgcg cttaatcagt attataccgg ctggcactac caccagcgcc
    14041 ggcaccagcg ccaggccaag cagagcgcct tcatagccgc cgacacggta gcagagatac
    14101 caggcggcga cgcccaaaaa gctgccgaca attaacgata aggcattacc cgacgcgtca
    14161 cgaaagccct tcattagcgc cagcagcagg ttcgcccagg cgatccccat ttgtaccagc
    14221 gcaaccagac gcaccagccc ttgatagtcc gtatgaccga acagtccctg gctaatcggc
    14281 gccgccgcca gcaggaagac cagcgccagc agcgtagaga accccaatac catcgcggag
    14341 gaggttccca ccacggtacg taactgcgcc gggtcatcat gatgttgtgc gacgagtttg
    14401 gtaacgccgt taaatatccc ggcgccagcc aatacgccca gcacggtaat catctggcgg
    14461 aagttacccg cttgtccgac gcccgacgga ccgaaagaga cggccagtag tttcaccacc
    14521 agcagtccgg cgccaatttt taccagcgta ctgaccgccg tccacaggga ggctttagca
    14581 agcgacatat caggagaaat aatttagcaa ggtagtaatc accgttcgtt gatcgacggg
    14641 cgcaaggtta taaaacagcg gcagacgcaa caaacgttcg ctctcttttg tggtgtagac
    14701 atcgtccccg ataaactcgc cgaatttatc gcccgccggg caatcatgta gcggaatgta
    14761 atggaatacc gccatgattt ccgcctcttt caggaaatta atcagcgcgc tgcgatcggc
    14821 gatatcccgc agtttgatgt aaaacatgtg ggcattatgc ccgcagtttt ccggaataga
    14881 aggcagctca atacgcccgg cgcgcgccag cggcgttaac gcatcgtagt aagtctgcca
    14941 cagcgacaga cgctgttgat tgatacgatc ggcggcctcc agttgcgccc acaggtaggc
    15001 agcctgcaga tcggacatca agtaactgga gccgatatcc cgccaggtgt atttgtccac
    15061 ctgaccacgg aagaactggc tacggttggt gcctttttcg cggatgatct ccgcgcgttc
    15121 aatcagcgta cgatcgttga tcagcgtcgc gccgccttcg ccgccagcgg tgtaattttt
    15181 ggtttcatgg aagctaaaac agccgatgtg accgatcgtc cctaacgcgc gccctttgta
    15241 cgtggacatt acgccctggg cggcgtcctc gacaacgaac agattatact tatccgccag
    15301 cgccatgatg acgtccattt cacaagcgac gccagcgtag tgtaccggca cgatagcgcg
    15361 ggttttatca gtaatcgccg cctcaatcag cgtttcgtca atattcatcg tatccggacg
    15421 aatatcgaca aacacaattt tcgcgccgcg caggacaaaa gcgttagcag tggagacaaa
    15481 cgtaaagctc ggcatgatca cttcatcgcc gggctgaata tccaacaaca gggccgccat
    15541 ctccaaagac gcggtacagg aaggcgtcag caacaccttc gcgctgccga aatgttgctc
    15601 cagccactgc tggcaacgac gcgtaaagcc gccgtcgccg cacagtttgc cgctgctcat
    15661 tgcagactgc atgtattcga gttcggttcc caccaccggc ggcgcattaa aaggaatcat
    15721 gttgtcacct gtataaccag tacgcagtgc tttcgatgtt ggcaccgctt tgtatgtaac
    15781 gtttaagcgc ggcggtgttg cccaactggg tcgccacccg caatgttgct ttgccgcgac
    15841 tctgcgccca acagatcgcc gcctgcataa gttccgctcc cgcgccgcgt ccggccaaca
    15901 ggccaatgcg cacgtcggta tcattcaatt cccgcagcga gacgtaacca cggatagcgc
    15961 ctgtctccgt gcgaagcacc aggcattggt gatcaaacgt gccgcgtacc gcattctcaa
    16021 tccactgggc gtaaaaacgg gcgctggcgt cgggcgcata ccacggcgcg cgaaaacgac
    16081 tctgcgtaaa cgcctctccg gccaactgac gcaaagcagg aatgtccgta agatgtgcaa
    16141 tttccgcgcc atgctggtcg cgatgccctt ttaccggcaa cgcaaaatcc acctcgcctt
    16201 caaccaaaga gaatcccagc gattgcaacg ccgacagcca ggcgatgttt tcagccggca
    16261 cttttgcctg cacgcgttgc catgcctgca gcgcttctgg cgttaattcg ggcgctgagg
    16321 catcgatacg cacaatgccg ttattcacgc caaagaacgt attttcccag tgtaacggtt
    16381 caatactggc gcggacgggc acggagcaac tccagtaaat attggccata gccggttttt
    16441 tcaagctgac tggcggcgcg tttcaaacca tcatcatcca gccagccgtt gcgccaggca
    16501 atctcctcca gacaggcaat tttgaagccc tggcgctttt ccaccgtctg cacaaaagtg
    16561 ctcgcctcaa tcagactgtc gtgggtgccc gtatccaacc aggcgaagcc gcggcccagc
    16621 agttcaacgg tcagcttacc ttcctccaga tacatctggt tgatagaagt gatctccagc
    16681 tcgccacgcc cggacggttt cacgcgcttc gcatactcga cgaccttgct gtcatagaaa
    16741 tagaggccgg tgaccgccca gttagattta ggctgtttcg gcttttcttc cagcgagagc
    16801 gcgcgaaaat catcgtcaaa ctccacgacg ccaaagcgtt ccgggtccat gacctgatag
    16861 ccaaatactg tggcgccttc ggtacgcgcc gcgacctgac ggagtttggg gctaaagccc
    16921 tgaccaaaaa agatattgtc gcccaatact aggcatgagg gttcaccgtt gaggaacgtt
    16981 tcgccaatga taaaggcctg cgccagcccg tccggactgg gctgctcggc ataatgtaaa
    17041 tcgataccga atgctgcgcc gtcgcccaac aaacgctgaa agtcgcgttt atcctccggc
    17101 gtggtgatga tcaagatctc acgaatgccc gccagcatta gcaccgataa cggatagtaa
    17161 atcatcggtt tatcgtagac gggcagaagc tgctttgata cgccgcgcgt aatgggatgc
    17221 aaccgggtac cggaacctcc cgccagaatg atgcctttca ttcgtttctc ctccaggagt
    17281 aagagcctgc cgtttagcgt ttcagaccta agcgttcgcc ctgataactg ccatcctgca
    17341 cgggtttcca ccaggcctca ttggcgagat accactgaac ggtttttcgc atcccgcttt
    17401 cgaaggtttc ctgcggcgtc cagcccagct cgcgggcgat tttcgacgcg tcgatggcat
    17461 aacgtaagtc atggccgggt cgatcgtcga cgaaggtaat cagatcgtga taattcgcca
    17521 caccctgcgg tttttgcggg gccagttcct ccaacagagc gcagatcgtc ctgaccacat
    17581 ccagattttt acgttcgtta tgaccgccga tattatacgt ttcgcccacc gcaccgttcg
    17641 tcaccacgtg atacaacgca cgggcatgat cctccacata cagccagtcg cgaatttgct
    17701 gaccgttgcc atagaccggc aatggtttac ccgccagcgc gttcagaatc atcagcggga
    17761 tcagtttttc cgggaaatgg tagggcccgt agttattaga gcagttggtg acaagcgtag
    17821 gcagaccgta ggtacgtaac caggcgcgta ccagatggtc gctgctggct ttggaggcgg
    17881 aataagggct gcttggcgca tatggcgtgg tttcggtgaa gaaatcgtct gcagtatgca
    17941 gatcgccata cacttcatcg gtggagatat ggtggaagcg gaacgccgct ttagcgtccg
    18001 cgtcaagcgc ggaccagtaa gcgcgagcgg cttccagcaa ggtgtaagta ccaacgatat
    18061 tcgtttcaat aaacgccgcc gggccgtcga tggaacggtc tacatggctt tccgccgcca
    18121 ggtgcatcac gctatcgggc tgatactgct ggaaaacttg ctccagtgat gcccgatcgc
    18181 agatatccac cttctcaaag gcgaaacggt cgctttgcgc caccgacgcc agagacatca
    18241 ggttgcccgc ataggtgagt ttatccacca ccaccaccgc gtctgccgtt tcatggatga
    18301 tatgccgcac caccgcagat ccgataaagc ctgcgccgcc ggtcaccaga atgcgtttca
    18361 tcagcgccag acccctttgg tatcaaccac ataacgttga tgaaccgcat cgccgggaat
    18421 cgctttaaat tcgtcgtgat cgaccagcat caccagcaca tcggcggcgg ccagcgccgc
    18481 gtccagtttc gccagcgtgc aaagtccgtc caattttttc ggcaactgac ggatattcgg
    18541 ttcgacgacc agggtttcgc cgctgtgcca gcgggcgata ctttgcgcga tccccatcgc
    18601 cgggctttcg cgcagatcgt cgatattcgg cttaaaggcc agcccaaaac aggcgatttt
    18661 cacttcgctg gcgcgtttat cggtggctgc caggcaatct gcgaccgcgg cttttacctg
    18721 atcgaccacc cagtgcggtt tgccgtcatt cacttcacgc gcggtgcgaa tcagtctcgc
    18781 ctgctgcgga ttttgcgcca caataaacca cggatcgacc gcaatgcagt gcccgccaac
    18841 gcctgggccc ggctgcaaaa tattgacgcg cggatggcgg ttcgccaggc ggatcaattc
    18901 ccagacgtta atcccctgtt cggcgcaaat cagcgacaat tcattcgcaa aggcgatatt
    18961 cacatcacgg aagctatttt ccgtcagctt gcacatctct gcggtgcgcg agttggtgac
    19021 aacgcattcg ccctcaagga aaattttgta cagcgcgctg gcgcgagccg aacatactgg
    19081 cgtcataccg ccaatcacgc ggtcattttt aatgagttcc accatcacct gacccggcag
    19141 cacacgctcc ggacaatagg cgatattcac gtcggcctgc tcgcccgcct gctggggaaa
    19201 ggtcagatcc gggcgcatcc cggccagcca gccagccatt tgctccgttg cgccgaccgg
    19261 cgatgttgat tccagaatca ccagtgcccc tttttttaat accggcgcaa tggatttcgc
    19321 cgcggcttcc acataggcca tgtcagggtc gtgatcgcct ttgaatggcg tcggcacggc
    19381 aatcaggtac gcatcggcct cgacaggtgt cgtcgtcgca cgcagaaagc cgccttccac
    19441 cgccatcttc accacattgc ccaacgccgg ctccacgatg tgaatttcac cgcgatttat
    19501 ggtgtctaca gcatgttggt tgatatccac gccgataacc tgcttctggc gggaagcaaa
    19561 agcggccgca gtcggtaatc cgatataccc cagcccaata acagaaatgg tcgtaaaact
    19621 cataacgata cccgataact ttttaacgcc tgtaaaatgc gcgcgcatga ttgcccgtca
    19681 ccataaggat tatgggcgcg gctcatggtt tgatattcat tttcgtcgtg cagcagacgc
    19741 ataacttccg ccacaatgcg ccgggagtcc gtgccgatca gtcttaccgt accagcggta
    19801 atggcttccg gacgctctgt ggtttcacgc atgaccaata ccggcttacc taatgacggc
    19861 gcttcttcct gaataccgcc ggaatcggtc agaatgagcc aggcgtgatt catcagccag
    19921 acaaaaggta agtagtcctg cggctcaatc agtaccacgt tttcaacatg gccgaggata
    19981 cggttgacag gttcgctgac gttgggattg agatgcaccg gatagacaat ttgcacattc
    20041 tggttcgcgg cggcaatttc cgccagcgcc tggcagatat gctcaaagcc ctgaccaaag
    20101 ctttcacgcc gatgaccggt caccaaaatc atcttcttat tcgcgttgag gaaaggatac
    20161 tgctcggcca gttcagcctg taatgtatcg ctcgtcagaa cgcgatcgcg tacccagatc
    20221 agcgcgtcaa taacggtatt gccagtgaca aaaatgcgct catccggaat gttctcccgc
    20281 aacagattct gccgcgagtt ttccgtcggc gcaaagtggt acatcgccag atgtccggtc
    20341 agcgtgcggt ttgcctcttc cggccagggg gaatagagat cgccggttcg caacccggct
    20401 tctacgtgcc ctaccggaat tcgttgatag aaagccgcca ggctggtagc aatcgtagtg
    20461 gtggtatctc catgaaccag caccacatca ggtttaaaat ctgccaggat cggctttaat
    20521 ctctccagaa ttcggcaggt aatttccgtc aacccctgtc ccggctgcat aatgttgaga
    20581 tcgtaatcag gcacaataga aaaaagagtt aatacctgat caagcatctc ccgatgctgc
    20641 gcagtaacgc atactttggc ctcgaaatga ggatcttttt ccagcgcatg gaccagaggc
    20701 gccatcttaa tggcctccgg tcgtgtacca aatacagtca gtactttcac atcgattctc
    20761 ttcgaataga cagtaggggc ccagccccct actgcagagg tgttgctaaa tcgtgcggcg
    20821 acgggttaag gcaacgcccg caccgattag cgccccaacg ataccccaca taatcatcag
    20881 gaaggctcgg cgtgggctat cacgttttac cggttcttcc ggcgtacgca aataacgata
    20941 ggtctgaaaa cgagggtcca gggtcggccc cacattaagc gtattcaaca ttgcccgatt
    21001 ttgaaagtag tccaaatcga acgcagggcc aaccgcttgc agattttcaa gacgcgcctg
    21061 caacataggg cgaccgagta aaaaaagctc tgagtccggt aattcatccg ccgggacatc
    21121 tgtcgcgcta cgagaaatat tatgttgttc cgcaattttg agcgcctgct caatactgtt
    21181 tacacgacgc gaatagatcg ctttcgcaac ctcttcctgc cgtttgacct gggctttcat
    21241 ctgcacggta cgcgcagccc aggcaccttt taattcatca ttcagatggc tcgccgcccg
    21301 ctggctggcg aatgcgacat actgacgcag cagattattg gcatccggcg cagtttcagc
    21361 aatcagcctc acgttgtcgt tgatggcgcg tgtaaaatcg ccgggcgtaa actgtatgtt
    21421 attgatcagt tcatcaagca tcaccgcatc agctttgcta ttcccgacca ttcgctgctt
    21481 gtaatagtcc gtctgtaacc agaaatcgcg acgcgtatcc caggaggcaa gttgcatgat
    21541 gaactcttta tacgcttcat ccatcaccga gggcttatca gaagaagcag gatcggtctt
    21601 aatatccagg ttgcgcagaa actgctgctg ggagtaataa ccgcccaaca tatttacggt
    21661 tgggcgatcg gtgatcgccg tcgcactcca ctcctgacga gcaaaaaagg tataggctaa
    21721 cgcgataagg gcaaatagca ggccaatgcc gataatccag aatttgccag cccataaagt
    21781 acgaaacaac ccgcgaatat ccagttcatt ttcagcgctc accgcgcgtg cccccggtaa
    21841 tggttgtgtc atcgtatcct catttacttg gttaagtttg gccggttctt acgttgcctg
    21901 cgcaggcgac gcttcacacg cttaataaat ctcgccacct tccaggcccg cttaatgcag
    21961 tagccataga ggaagaatgc tagcaaaaag agcaccaaca taacccattc aggaacaaaa
    22021 tgagagtatt ctgccgttac gcctactccc gccagaatcg ccgctgcgag cgtaataaga
    22081 acaaatgcct ggcgggaagt aaaccctgct cgcataacca aatgatgaat atgttggcga
    22141 tcaggggaaa aggggctcat ccctttacgc agacggcgat acataatcgc caccatatcc
    22201 atcaatggaa tagcgataat ccatagcgcg gtaaccgggc tgatagagtg agttttcccc
    22261 tgcgtcgttt ccagtaagag ccagatgacg gtaaagccaa tcagtgtact accggcatca
    22321 cccataaaga ctttataacg ccgccccaaa ataccgagat taagcataat gtaaggcaga
    22381 atcgcggcga tcatggcaaa gcaccacatt gccagactag tctgaccatc aaaccataaa
    22441 atcagcccca tcgccgcaaa tgagacgctg gataacccac ccagcagtcc gtcaataccg
    22501 tccaccatat tgaaagcgtt gatcgccgcc catacggcaa acagagtaag gaaatagcca
    22561 aaggggccaa gcactaactc ccaaggccca aagatgtaac caaggctacc taagtgaagt
    22621 tttgcgataa ccatcattac aaccgcaata acagcctgaa ccacagcacg aatttttaca
    22681 ctgatatcaa aacggtcatc catcgcacca acaaaaacca atacaccagc gcaaataaga
    22741 tatagcgata agtgcggtat gtagtaatcc gagaggccaa acataaagca gattcctgca
    22801 aacacagaaa tcccgccgac taatgggata acgccctgat gtcgtttacg aaagtttggt
    22861 ttatccacta aaccaatttt tatggctact tttcgcgcaa gaaaaataaa aatggtcgtg
    22921 aataaaaaaa tactgattag ctcagataaa gcggtgagta acttcacagt gtatgtgctc
    22981 tcagcatata tcatttcctt aaagtataat gcgttacgcc agctcctaga agagacctgt
    23041 tagaacatta cactttttac cgcaaacaat gtgtattgtg catggtgtta ctctgtagcg
    23101 catatcccga tgaccagttt atatgacatg acgccaggat gaatcgcaaa acaaaaacgc
    23161 cacgtaaaaa cgtggcgttt tcaggtaaag accaggttat gagcgcttca tcatctcgaa
    23221 aaagtcgtca ttagttttgg tcatcgccag tttgttaatg aggaattcca tcgcgtcaat
    23281 ctcacccatc ggatggatga ttttacgcag gatccacatt ttctgcagct cttcctgagt
    23341 ggtgagcagc tcttctttac gggtaccgga acggttgtag tcgatagccg ggaagacacg
    23401 tttttcagcg atcttacgcg agagatgcag ctccatgtta ccggtgcctt taaactcttc
    23461 gtagataact tcgtccatct tggaaccggt atcgattagc gccgtcgcga tgatagtcag
    23521 gctaccgccc tcttccacgt tacgcgccgc gccgaagaag cgcttcggac gatgcagggc
    23581 gttagcatcc acaccaccgg tcagtacttt accggaagcc ggcaccacgg tgttgtaggc
    23641 acgcgccaga cgggtgatgg agtcgagcag gatgatgacg tctttcttgt gttcaaccag
    23701 acgtttcgcc ttctcgataa ccatttcggc aacctgaacg tggcgggatg ccggttcgtc
    23761 aaaggtagag gcaaccactt cgcctttcac cagacgctgc atctcggtta cttcttccgg
    23821 acgttcgtca atcagcagca ccatcagcac gcagtctggg tggttatacg cgatgctctg
    23881 cgcgatgttc tgcagcagca tggttttacc cgccttcggc ggcgcgacaa tcagaccgcg
    23941 ctggccgcga ccgatcggcg aagccagatc cagaacgcgc gccgttaagt cttcggtaga
    24001 accgttacca cgctccatac gcagacgaga gtttgcgtgc agcggggtta agttctcaaa
    24061 gaggattttg ttacgggcgt tttccggttt gtcgtagtta acttcgttaa ctttcaacag
    24121 cgcaaaatag cgttcacctt ctttcggcgg gcgaatctta ccagaaatgg tatcaccagt
    24181 gcggaggttg aaacggcgga tttggctggg ggaaacgtag atatcatcag gaccggcgag
    24241 gtaggagctg tctgcagaac ggaggaaacc aaatccatcc tgcaatatct ccagcacacc
    24301 gtcgccaaag atatcttcgc cactctttgc gtgctgcttc aggatggcaa aaataatgtc
    24361 ctgcttgcgc atacgggcca ggttttccag ccccatactt tcgccgagag tgatcagctc
    24421 agaaaccggc gtattcttta attcggtaag attcataatg gtgtgagttc ttaaacttgg
    24481 ggtaaatctc gaacttaatg ttgtgaatgg tatggcaggg tcatccatgc ctgtttacgg
    24541 ctatcaactc atgtctgttc gctgtctggt cacaggaaag tacgcagaac tgaaacgaca
    24601 agacggaatg agcgaagagc caggaatctt tccacttctc gtgcgagaaa aaacgggaag
    24661 tgacggataa aaccagattc aaacttaata aggtatgttt aattcgaagt caatactaac
    24721 ttagcacgac tcagaccggg cgtccagaga tcctgacaat ttaagaataa cgtaaggaca
    24781 acagacgcca cgaaactgcc tgatacctta atcattcgtc gaatgacaga cgcctgacca
    24841 tacagcgcct ttgtcattcg acgtataaaa ggtattacgc cagattggcg tcgagaaact
    24901 ctttcaactg acctttagac aatgcgccta ctttggttgc cgccacttcg ccgtttttaa
    24961 acagcagcag agtcggaata ccgcggatgc catatttagg cgcagtacct gggttctggt
    25021 caatgttcag tttggcaacg gtcaatttgc cctgatattc gtcagcgatt tcatccagaa
    25081 tcggagcgat cattttacac ggcccgcacc actctgccca gaaatcaacg aggatagccc
    25141 cgtccgcttt gagtacatcc gtgtcaaaac tgtcgtcagt caggtgaata attttatcgc
    25201 tcatatataa ctccacagga ataagcctgg cgtgttggtg tagcattaac caacgaggtg
    25261 ctgatgttaa cttcgccaac aaaggttgac tttatttcac cggatacgct ttcgtaaagc
    25321 aatagtaagc tgatattcta ccacactatg agcaaaacac atttaacaga acagaagttt
    25381 tccgacttcg ccctgcaccc acaggtggtt gaagcccttg aaaaaaaagg gttttataat
    25441 tgtacgccca ttcaggcact ggcccttccg ctaacgctgg cgggtcgtga cgttgcaggg
    25501 caggcgcaaa ccggtaccgg gaaaacgatg gcgtttctga cgtcaacgtt tcattattta
    25561 ctttctcatc ccgcgatcga cgatcgcaag gtgaaccagc cgcgcgcgct gatcatggcg
    25621 ccgacgcgtg aattagccgt acaaattcac gcagacgcgg agccgctggc gcaagcgaca
    25681 ggcttaaaat taggcctggc ttacggcggc gatggttacg acaagcagct taaagtgctg
    25741 gaaagcggcg ttgatattct tattggtacg acgggccgat tgatcgacta cgccaaacaa
    25801 aaccacatta acctcggcgc cattcaggtc gtcgtactcg atgaagccga tcgcatgtac
    25861 gatttgggct ttattaaaga tatccgctgg ctgttccgtc gtatgccgcc ggctgcgcag
    25921 cgtctgaaca tgttgttctc cgccaccctg tcttatcggg ttcgcgagct ggcgtttgaa
    25981 cagatgaaca acgccgaata tgttgaagtg gaaccggagc aaaagaccgg ccaccgcatt
    26041 aaagaagagc ttttctaccc ctctaatgaa gagaaaatgc gtttactgca aacgctgatc
    26101 gaagaagagt ggccggatcg cgccattatt ttcgccaaca ccaagcatcg ttgcgaagat
    26161 atctggggac atctggcggc agatggccat cgtgttggtc tgctgaccgg cgacgtcgcg
    26221 cagaaaaagc gcctgcggat tctggatgag ttcacccgcg gcgatctgga tattcttgtg
    26281 gcgaccgatg tcgcggcgcg cgggttgcat atccccgccg taacgcacgt ctttaactac
    26341 gatctgccag acgattgtga agactatgtt caccgtatcg gtcgtaccgg tcgcgctggc
    26401 gccagcggac attccatcag cctggcttgt gaagagtatg cgctgaatct gcccgctatt
    26461 gagagctata tcggccactc gattccggtc agcaaataca atccggaagc gctcatgaac
    26521 gatctgccca agccgttgcg tctgacgcgt tcgcgtcctg gcaatggtcc gcgccgcgct
    26581 ggcgctccgc gtaatcgtcg tcgttcaggt taagaaaagt tatgccatac acaaaatcat
    26641 ttagcctgta tcaaggcggc aagaaaacaa atcccgatga gcttaggaag agtacgcagc
    26701 caacacggat acaggttgaa ggatgaagtg tatgaattcc acctcgttgt atgccgccat
    26761 tgatctcggt tccaatagtt ttcatatgct ggtcgtgcgc gaggcggcgg gaagcatcca
    26821 gacgctgacc cgaataaaac gcaaggtgcg tctggccgcg ggtctgaaca acgacaacca
    26881 cctttcagcc gaagcgatgg aacgcggctg gcaatgcctg cgtctgtttg ctgaacgttt
    26941 gcaggatatc ccgcagccac aaatccgcgt ggttgccacc gcaacattgc gtctcgccgt
    27001 caatgcaggt gaatttatcg cgaaagcgca gactatcctt ggttgtccgg tgcaggttat
    27061 cagcggcgaa gaagaggcgc ggctaattta tcagggggtc gctcatacca ccggcggcgc
    27121 agatcagcga ctggtggtgg atatcggcgg cgccagcact gaactggtta ccggcactgg
    27181 cgcgcaaacc acgtcgctgt ttagcctgtc gatgggctgc gtaacgtggc ttgaacgcta
    27241 ttttagcgat cgtaatctgg cgcaagaaaa ctttgatgat gcggagaaag ccgcgcgcga
    27301 tgtactgcgt ccggtcgccg atgaactgcg ttttcatggc tggaaggtct gcgtgggtgc
    27361 ctccggcacc gtacaggcat tgcaggaaat catgatggcg caggggatgg acgagcgcat
    27421 tacgctcgcc aaactgcagc agctaaaaca acgcgcgata cagtgcgggc gtctggaaga
    27481 gctggaaatc gaaggcctga cgctggagcg cgcgctggtt ttcccaagcg ggctggctat
    27541 tctaatcgcg atatttaccg agctgaacat ccagagcatg acgctggcag gcggcgcgtt
    27601 acgcgaaggg ctggtgtatg ggatgttgca tctggcggta gatcaggata tccgcagccg
    27661 cacgctgcga aacattcagc gtcggtttat cgtcgatacc gatcaggcaa atcgtgtggc
    27721 gaagctggca gataacttcc tcaaacaggt agaaaatgcc tggcatattg aacctatcag
    27781 tcgtgaactg ttgcttagcg cttgccagtt gcatgagatc ggtctgagcg ttgattttaa
    27841 acaggcgccc tatcatgccg cctatttagt acgccatttg gatctgcctg gctatacgcc
    27901 cgcgcagaaa aagttgctcg ccaccctctt actgaatcag accaatccgg tcgatctctc
    27961 ttcgcttcat cagcaaaacg cggtaccgcc ccgtgttgcg gaacagctat gccgtttgct
    28021 gcgactggcg attctttttg ccggtcgccg tcgtgacgat ctggtaccag aaattacgct
    28081 acaggcgcta aatgaaaatc tgacgttaac cttgcctggc gactggctgg cgcatcaccc
    28141 gctgggtaaa gagttgattg atcaggaaag ccagtggcaa agctatgtac actggccgct
    28201 ggacgttcgc taaccgtagt ctgattgccg gatgacgctt cgcttatccg gcctacgatt
    28261 tcgctcgctt tgccgccatc atggctttca gattagccag gtgactttgc cctttttgca
    28321 ttcgctcctc agcgcttacc actttgcgct cctgctccca gattaaatca tcctgcggca
    28381 gttctaacag gaagcgactg ggttccgggc gcaccagttc cccatactga cggcgctctt
    28441 tacataatgt aaaggtgagc tctttctgcg cacgagtgat cccgacatag gccagccgac
    28501 gctcttcctc aatattgtct tcgtcaatgc tgctttgatg cggcaaaaat ccttcttcca
    28561 ttcccaccat atagacatac aggaattcca gtcctttcga cgcatgaagc gtcatcaact
    28621 gtacctgatc cagctcttct tcgctctcgc cgcgctccat catatcgcgc agcgtaaagc
    28681 gtgtaaccac ctgggtgagc gtcatcggct catcgagttc gttgccttcc agcatctcag
    28741 tcatccagct aaagagctgg ttaacgtttt tcatacgcat ttccgccgct ttggggctcg
    28801 gcgaggtttc gtacaaccag gattcatagt caataccgtg gatgagatcg cgcacggcgg
    28861 cgacaggctc acgttcggcc agacgctgga tttcccccag ccagtgggta aaacgcgtca
    28921 atgaatcgta accacgtccg gtcagcttct ggctaagccc catatcaaag ctggcggtaa
    28981 acaggctttt attacgcgtc attgcccatt cacccagctt ttgcagagtg gccggaccga
    29041 tttcgcgttt tggcgtattc acgatgcgca ggaaagcgct gtcatcatcc gggttggtca
    29101 acacccgcag ataggccagc aagtctttaa tctccggacg ggagaaaaat gaggtgccgc
    29161 cggaaatttt gtacggaatg cggttctgca tgaggaattt ttcaaatacc cgcgactgat
    29221 gattcccgcg atacagaatg gcgtaatcct tgtactgggt cttgttcaca aagtgatggg
    29281 caatcagttc gccggtaacg cgctcagctt catgctcttc attgtttgcg cttaacactt
    29341 tgagttccgc gccgtaaccg agttcggaaa agaggcgctt ttcaaagacg tgcggattgt
    29401 tggcgatgag aatatttgcc gctttcagga tgcggcccga agaacgatag ttttgctcca
    29461 gcttaatcac ctgcagcgcc ggaaaatcct ggctcagtaa caccaggttt tgcggacgcg
    29521 ccccgcgcca ggagtagata gactgatcgt catcgcctac gaccgtaaag cgcgcgcgtt
    29581 gcccaaccag cagcttaacc aactcatact ggctggtgtt agtatcctga tattcatcca
    29641 ccagcagata acgaatttta ttctgccagc gctcgcgcac ctcgtcattg cgttgcagca
    29701 gcagcgtcgg cagcaaaatc aaatcatcaa aatcgagaac gttacatgcc ttcatatggg
    29761 cgtcgtaaag cccgtagcag tgggcaaaaa tacgatcgcg ttcacctttc gcccccgccg
    29821 ctgcctgtgc aggcgttttg agatcgtttt tccagttgga gatcgtggag atcagctgtt
    29881 gcaacagaac cttgtcgtct tcgatcaggc cttcggtcag ctctttgagc aaggcgacct
    29941 ggtcggtatc gtcaaacaat gaaaagttcg atttcatccc cagcgcagcg tactcgcgct
    30001 taataatatc cagccctagc gtatgaaagg tggagatcat caaaccgcgc gcttccttac
    30061 ggccgagcgt ctgcccgaca cgttctttca tctcacgcgc tgccttgttg gtaaacgtca
    30121 ccgccgcaat atgccgggcc tgatagccgc atccgcggat caggtgggcg attttattgg
    30181 taattacgcg agttttacca gaacccgctc ctgccagcac caggcagggt ccggtgacga
    30241 attcgacagc gtgttgttgg ccaggattta aacgcatggg aatagtgctc aatcttcgaa
    30301 cgggggaggg attgtagcag aaagcgaggc ccagagaaga ccaggctgct ttttcaggca
    30361 gcctggaaaa ggtcaatcag caggctctgg cggcaagcga cgtatagcca ttacgctgtg
    30421 cgctcttgat ccaactgtaa gaacccatta gcgcgatcac cgtcagcaga acatactcaa
    30481 gcgacatcgc ataaacgccc tgtactgcat agatcacgac gctaattaca tcaataatca
    30541 cccacagcag ccagttttcc acgtacttgc gggtcatcag caccatcgcc gcaatcgaca
    30601 acaccagcat ggtggaatcc cagaacggga acgcgtccgg ctggagttca ggcatcgcca
    30661 cctgcatacc taccgtttgc agcagagcga gcataacgcg ggtcaacata gcgaagaccg
    30721 gatcgataaa ccacgtcatc agcagaatgc taataataca tatgcccccc aacctccatg
    30781 tttgttgaca agaaagccag cgtactttca gagcggcttc ccgggcgtca ttctgccggc
    30841 tccatgcgta ccagccgtaa atattcgccg caaagaaaaa cacctgaagt agcaagctgg
    30901 catacagttg aatctgaaaa aagatggcgg caaacagagt gacgttaatc aagccaaaca
    30961 ggtaattaat gattttttcc cggctggcgc accagatgca caataagcca aagacggtac
    31021 cgatagcctc aatccacgat agcgcatacc caccctcgcc gagaggaatg ttgaccatta
    31081 cattgttaat gctgaaaaag tccatcattg ctctccttgc aaactatcga aataaatggc
    31141 ctgaagcgcc agagaaatct ggcgctcttc accttgctgg cacaaggttt cctgctgaac
    31201 ataatggtta atgctgctct ccagacagcc actatgcgcg acgaccacgt ttagcaacga
    31261 cgcggtacgc agcccacgta acgctcccac caccatcagc gcggcggttt ccatatccgc
    31321 gccgagaact cccctggccg accattcggc atccagttca gcttcgcgat cggtataaaa
    31381 actgtcatgg ctgcgcacca gcccgcaaac ggcagagatg ttcatctgtt tcgcctgctg
    31441 tatcagcgtg gcggtaagat aagggtccgc acaggccgga taactggcgg gcgcataggt
    31501 tttgctggcg ccgtcgtcag ccaccgcgcc gtgggcgatg atcacatcgc ccaacgccag
    31561 cgagtcctgc aacgcgccgc aactaccgat acggattagc gtgttgacgc caacctggcg
    31621 taactcctca atggcgatag cggttgacgg tccgccgatt cccgtggaga gcacgactat
    31681 ttcaaccccc tggtaccagc cgcgcgccgc gcgaaactcc cggttttgcc ccagaatctc
    31741 agccttatca agaaaacggg cgattctatc cacccgcccg ggatcgccgg gcaaaagcgc
    31801 atatttcgcg cgggtcatgc ttgtgttaag ccgaatatgg ggttgcatct ccctctcctt
    31861 attgttctga gaggttcaga tttccgcctc ctgtttgagt ttttcaggag ccagtaaaat
    31921 gatccgctca ccgtcggtat cgataatgtt cagcgatttc agatcgtgca gtatccggtt
    31981 gatactgcgc gtcgtcgccg caaattcctg accaagattc tgcttatcaa gcaaaatagt
    32041 ggttgattca tattgttgat aacgcagcca taatgcctgg catacgcgct gatgcagcga
    32101 gtacaaattg tcgctactgg cctttttcga caactggtaa tactgttggc tgaaaaaccg
    32161 cagcattcgc tggttaaagt ggttatccag cgtcagccag cggcaaaaat gtgcttgcgg
    32221 caggctaagt agctgtacat tgccgacggc tacgacagaa cagatgtaat gccgcgactc
    32281 aaatatctct agctcgccca gcatgtctcc tttgccataa cgcgcctgcc ggtaacggcg
    32341 tccatcttca gcttcgtaaa aaacatccac ttcgccggcc acgatgagcg aaaattgcta
    32401 gcatgtttcc ccctggcggc agataagcgc gccgcgggaa atgtcgtcaa atcgccagca
    32461 ctgcatgatt tccaacgggc agtatttgag taattcatag agcactgggt cgcgtacgac
    32521 ctggcgtagc cctaaaagcc agtcgtctgg aaattctgcg tttttcatta tgttcatggt
    32581 atctcgcccc ttgtcagaaa ggacaggacc gtcgtcccgc ccatccgaaa tacgcccgct
    32641 aaaaatgccg cttatctccc ggttcattaa atcaggcggg acatctgtcc tgtaatggcg
    32701 aagagtatat gtctgacggc ctaaggagtg ataaagtgac ggccaatctt tgcgacgtga
    32761 gaacacaata atggcaaaaa tggcagcagc actgcatatt cttgtaaaag aagagaaact
    32821 ggctttagat cttctggagc aaattaaaaa cggcggcgat tttgagaagc tggcgaagaa
    32881 gcattctatc tgcccatccg gtaaaaaagg cggtcattta ggcgaatttc gtcagggcca
    32941 gatggttccg gcattcgata aagtagtctt ttcctgcccg gtactggagc caaccggccc
    33001 actgcatacc cagttcggtt accacatcat taaggtattg tatcgtaaat aaaaagccgg
    33061 gtggcggcta cgccttaccc gacctacatc gtctgcttga ttttgtcggt cgggtaagcg
    33121 ctagcgccac ccgacaaggt atatcaaccc gctaccgcaa tacgcttcat atccgtcata
    33181 tagccgcgca gtttcttacc tacctgctca atcgcatgac tacgaatcgc gtcgttcacg
    33241 tcgcgaagct gtgcgttgtc taccgcgcct tccgggatag cactacccag atcgcccggt
    33301 tgcaattccg ccataaacgg tttcagtagc ggtacgcaag cgtaagagaa caggtagtta
    33361 ccgtattctg cggtatcgga gataaccacg ttcatttcgt acaggcgctt acgggcgatg
    33421 gtgttggcaa tcagcggcaa ctcgtgcagt gattcgtagt aagcggattc ttcgatgatg
    33481 ccggaatcga ccatggtttc gaacgctagc tcaacgcccg ctttcaccat cgcgatcatc
    33541 agaacgcctt tatcgaagta ctcctgctcg ccgattttac cttcaaactg cggcgcggtt
    33601 tcgaacgcgg ttttaccggt ctcttcacgc caggtcagca gtttcttatc gtcgttcgcc
    33661 cagtcagcca tcatgccgga agagaattcg ccggagatga tgtcatccat gtgtttctgg
    33721 aacagcggcg ccataatctc tttcagctgt tcggacagcg cgtaagcacg cagtttcgcc
    33781 gggttagaca gacggtccat catcagggtg atgccgccct gcttcagcgc ttcggtgatg
    33841 gtttcccagc cgaactgaat cagtttttcg gcgtatgccg ggtcggtgcc ttctgccacc
    33901 agcttgtcga agcacagcag agaaccggcc tgcagcatac cgcacagaat ggtctgctcg
    33961 cccatcaggt cagatttcac ttccgccacg aaagaagatt ccagtacgcc cgcacggtga
    34021 ccgccggtgg ccgcagccca ggctttagca atcgccatac cttcgccttt cggatcgttt
    34081 tccgggtgaa cggcgatcag cgttggcaca ccgaagccac gcttgtattc ttcacgtact
    34141 tcggtgcccg gacacttcgg tgccaccatc accacggtga tgtctttacg gatctgctcg
    34201 cccacttcga cgatgttgaa gccgtgggag taacccagcg ctgcgccgtc tttcatcagc
    34261 ggctgtacag aacgtacaac gtcggagtgc tgtttgtccg gcgtaaggtt aaccaccagg
    34321 tcagcctgcg ggatcagctc ttcgtaggtg cctactttga agccgttttc ggtcgcttta
    34381 cgccaggagg cgcgcttctc agcaatagct tctttacgca gggcgtagga aatatccaga
    34441 ccggagtcac gcatgttcag gccctggttc agaccctgag cgccacagcc gacgatgacc
    34501 acttttttac cctgcaggta gctcgcgccg tcggcgaatt cgtcgcggcc cataaagcga
    34561 catttaccca gctgcgccag ctgctggcgc agattcagtg tattaaagta gttagccatg
    34621 atggtgtact ccgtgatgtt gtgttgtcgc gcttattgtt cggtttacag attgctatct
    34681 gtgcgaatga acccacatta caacaggaaa tttattgcgg aaattgatat attcacaacg
    34741 ttatgttgcg gtttatgcaa cgtcaaaaac cggaggtctg tctgtggatt tacgcgatct
    34801 aaaaaccttc ctgcatctgg cggaaagccg ccattttggc cgcagcgcgc gggcgatgca
    34861 tgtcagtcct tccacccttt cccgacagat tcagcggctg gaagaagacc tcggccagcc
    34921 gctgtttgtg cgcgataacc gtacggtcac gctgaccgaa gcgggtgaag agctgcgagt
    34981 gtttgcccaa cagacgcttt tgcaatatca gcagttgcgc cataccctcg atcagcaggg
    35041 gccgtccctt tccggcgaac tccatatctt ctgttcagtg actgcggcgt acagccacct
    35101 gccgccgatt ctcgaccgtt ttcgcgccga acacccttct gttgaaatca aattgacgac
    35161 cggagacgcc gccgatgcga tggaaaaggt ggtaacggga gaagcggacc tggcaatcgc
    35221 cggcaaacca gaaacgctgc ccggcgcggt ggcgttttcg atgctggaaa atctggcggt
    35281 ggtgctgatc gccccggcgc tgccctgccc ggtgcgtaat caggtgtcgg ttgataagcc
    35341 cgactggtca acggtgccgt ttatcatggc cgatcaggga ccggtacgcc gccgcattga
    35401 gctgtggttt cgccgccata aaatcagcaa tccgcagatt tacgccaccg tcggcggtca
    35461 cgaagcgatg gtctcaatgg tggcgctggg ctgcggcgtg gcgctgctgc cggaagtggt
    35521 gctggaaaac agtccggagc cggtgcgcaa ccgggtgatg attttagaac gcagtgatga
    35581 aaaaacgccg tttgagcttg gcgtctgcgc gcaaaaaaag cggctgcatg agccgctaat
    35641 tgatgcgttc tggaagattt taccgaatta gttttacggc cctaccatta cccgaacagg
    35701 cttcccaata cggctaagca tattcaccag agcatcaatg gtgaatttgc tgcatttctt
    35761 gttgacgaca tccgaaacgc gcggtcggga tatatgcaaa actgtagcaa cctcggcttg
    35821 cttcatctgg ttttgcgtaa tccagagggt aatttcttcc attagctgtt gtttaatggc
    35881 taacgtgttt tcgatttcat tcagggaatc agcgtaaaac ttttctgcgt cctgcttatg
    35941 aaaccccaaa tcagcaaaaa cattaccgcc agatggcgtc acatggcgaa aatcactatc
    36001 agttttggca atcacaagct gtttctccgt tgttgcacca cccggttata acgcgttctg
    36061 gcgatgtttt tatcatgctg actggtttgt tgcgtctgtt tttggaaact atgcaaaacg
    36121 tagagtgctt ctgcaaaatt agcgacatac ataacgcgat agataccatt gttgttacga
    36181 atacgaattt catttacccc agccccaatt tctgaaaacg gtttccagtc atcgggttca
    36241 attccatact gaattttgtg aagctgataa ccgactgctt tacgtaccgt tatgggaaaa
    36301 gccaggagat cctccagaga agatcccacc catcgaattt ctttttcatt ggagagagct
    36361 cgggtgagta acataacatc tttgtgtata aaattttata cattgttttt agcaggtgca
    36421 agtgatggcg gtgctaatga tatggagccg agtttcacca caagcagatt gggcgccttc
    36481 tggaaaacgt ctcgcaaaat gaaatgagtg gatgctccgg gctggcagga aagcccaata
    36541 actgagggaa gataatatct ggatattagg cccactttac tttgtgggcc cgaaaaacta
    36601 aacgctgaat taacccgcca gaaagaaccg gaacgccggg ttattgctct catcatggca
    36661 ttcatagccc agttcatgca gccgggtttc gaaatccggc tcatgatcgc ctaactcgaa
    36721 cgccgccagc acgcggccat aatcggtacc gtggctgcgg taatggaata gcgaaatatt
    36781 ccagtgcgtg ccaagcgtat gaaggaattt gagcaacgcg ccgggcgact ccggaaattc
    36841 gaaactatac aaacgctcct gtaatggctt ggaggggcgc ccgccgacca tatagcgcac
    36901 atgcagcttc gccatttcat cgtcggagag atccactacg ctataaccgc cgtcgcacag
    36961 ttgggtgata atctcttttc gttcctccag cccctgactg acgcgtacgc cgacaaaaat
    37021 acaggcatgt ttcgcgtcgg caaaacggta gttaaattcg gtgaccatac gcccgccaag
    37081 caactggcag aatttgagga agctcccctt ttcttccgga atggtcaccg ccagtaacgc
    37141 ttcgcgctgt tcccccagct cgcagcgttc agacacatag cgcaagccgt ggaagttgac
    37201 gttggcgccg gaaaggacgt gcgccaggcg ttcgccgcga atattgtgct gggcgatata
    37261 ttttttcatc cccgccagcg ccagcgcgcc ggacggctcc gccaccgcac gcacatcttc
    37321 aaacaggtct ttcatcgccg cgcagatcgc gtcgctatcg actgtaataa tgtcgtcgag
    37381 atattcctgg cacaggcgga aggtttcgtc gccgatgcgt tttaccgcca cgccttcagc
    37441 aaataaccca acgcgcggga gatccactgg atgaccggct tccaacgccg ctttcaggca
    37501 ggcggaatcc tccgcttcga cggcaatcac tttgatttgc ggcatcaatt gtttgatcag
    37561 taccgctacg cccgccgcca ggccgccgcc gccaaccggc acaaagacac gatcgagatg
    37621 cgaatcctgc tgaagcagtt ccagcgccag cgtgccctgc ccggcgatca ccattgggtg
    37681 atcaaacggc ggcacccagg taaaaccctg ctgctgcgcc agctcaatag ctttcgcttt
    37741 cgcttcatca aaattagcgc cgtgcaacag cacttcgccg ccaaaaccgc gtaccgcatc
    37801 gactttaata tccgccgttg cttttggcat gacgatcaga gacttcacgc caagccgcgc
    37861 ggaggagaac gccacgccct gtgcatggtt ccccgccgac gcggtaatca cgccgtgggc
    37921 tttttgttct tcggtcaatc cggccatcat cgcgtaagcg ccgcgcagct taaagctatg
    37981 taccggctgc cggtcttcgc gtttgacgag aataacgttg tccagacgtg acgagagctt
    38041 ttccattttt tgcagcggcg tcacctgcgc cgcttcgtat actggcgcgc gtagcaccgc
    38101 gcgcagatac tccgcccctt ccggcgcgac tgacagaggt tgagattccg ccatcatcaa
    38161 cctcccagtt tcgatttatc gcgcaccgcg cctttatcgg cgctggtcgc caggctggcg
    38221 taggcacgca gggcaaacga aacctgacgc tgacgatttt tcggcgtcca ggctttatcg
    38281 ccgcgagctt cctgcgcctc gcggcgtgcg gcgatttcag cctcgctcaa ctgcaactga
    38341 atgctgcggt tcgggatatc aatcgcaatg gtgtcgccat cttcaatcag cgcaatagtg
    38401 ccgccgctgg ccgcttccgg cgagacgtgg ccgatggaaa gacccgaagt accgccggag
    38461 aaacgcccat cggtgatgag cgcgcaggct ttgcccagcc ccatcgactt caggaaactg
    38521 gtcggataga gcatttcctg cattcccggc ccgcctttcg gcccttcgta gcggattacg
    38581 accacatcgc cttccactac tttgccgccg agaatcgcct ctaccgcatc gtcctggctt
    38641 tcgtaaactt tgacaggacc ggtaaattta aggatgctgt catccacgcc cgcggttttt
    38701 acgatgcagc cgttttcggc gaagttgcca tacagcaccg ccagaccgcc gtctttgcta
    38761 taggcatatt ccagcgagcg gatgcaaccc gctgcgcggt cgtcatccag cgaatcccag
    38821 cgacaatcct gagagaacgc ctgggtagta cggataccgg cagggccagc acggaacatt
    38881 tttttaaccg cttcgtcctg cgtaaccgtg atgtcgtact gttccagcgt ttgcggcagc
    38941 gtcaggccta atacgttttt cacgttgcgg ttcagcagcc cggcgcgatc cagctcgcct
    39001 aaaataccca gcacaccgcc ggcacggtga acatcttcca tatggtattt ctgggtactt
    39061 ggcgccactt tacacagctg cggcaccttg cgggacagct tgtcgatatc actcatggtg
    39121 aagtcgattt ccgcttcctg cgccgccgcc agtagatgca gaacggtatt ggtcgaaccg
    39181 cccatcgcaa tatccagcgt catcgcattc tcaaacgccg ccttgttggc gatgttacgc
    39241 ggcagtgcgc tttcgtcatc ctgctcgtaa tagcgtttag tcagttcaac aatccgctta
    39301 ccagcattga ggaacaactg cttccggtca gcatgggtcg ccagcagcga gccgttgccc
    39361 ggctgcgaca ggcccagcgc ttcgatcagg caattcatgg agttagcggt aaacatgccg
    39421 gagcaggagc cgcaggttgg acaggcggag cgttcaacct ggttactttg atcgtcagag
    39481 actttcgggt ccgctccctg aatcatggca tcaaccagat cgagcttgat gatctgatcg
    39541 gacagtttgg ttttcccggc ttccatcggg ccgccggaga caaagatcac cggaatattc
    39601 aggcgcagcg aggccatgag catccctggg gtgattttgt cgcagttgga gatacacacc
    39661 atcgcgtcag cgcagtgagc gttcaccatg tactccacgg agtcggcgat cagctcgcgc
    39721 gacggcagtg aatagagcat acccccgtgc cccatggcga tcccgtcatc cacggcaata
    39781 gtgttgaact ctttcgccac accgccggaa gcttcaatct gttcggcgac cagcttaccg
    39841 agatcgcgca gatgaacgtg acccggcaca aactgagtga atgagttcac cacggtgata
    39901 atcggtttgc caaaatcact gtcggtcatt ccggtggcgc gccacagcgc gcgggcaccc
    39961 gccatattac gaccatgagt ggtggtggcg gaacggtact taggcatgct ttatttactc
    40021 cccatctttt cccttcatac ttcacgccac aggtgcgttg gctgcctcac tccagtcact
    40081 tactacagta agc
//
LOCUS       DAJVKX010000032        38908 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.032, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000032 DAJVKX010000000
VERSION     DAJVKX010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 38908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38908
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.032"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..485)
                     /locus_tag="OPY25_001622"
     CDS             complement(<1..485)
                     /locus_tag="OPY25_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0927257.1"
                     /translation="MANLPETPQWESGIYQIEVSDPVLGGPDGISNRQAKQLASRTSY
                     LKQKVEKSGTDLAAHIAAVDPHTQYATKASPTFTGTPTAPTPANGDNSKKLATTEFVA
                     KALAALAGSAPETLDTLKELADALGNDPNFATTVLNKLAEKLAKDQNGADIPEPALFV
                     K"
     gene            complement(488..1066)
                     /locus_tag="OPY25_001623"
     CDS             complement(488..1066)
                     /locus_tag="OPY25_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HCS0927258.1"
                     /translation="MAEVLQLPPPLEGDISLRTLGRLAGRLDNIDLSVLMVGLVDIVD
                     SSALPWLGEQFSLFGDGWELAESDDVRRMLIKSAIELHRYKGTPWSIREIIRRFGFGE
                     VDLIEGTGQIGYDGRHTYNGLFVHGDAQAWAVYRVILQQPITNDQAALLRQTLAAFAP
                     ARCHLASLEYQSVAIRYNSTTRYDGSYNHGSS"
     gene            complement(1059..2162)
                     /locus_tag="OPY25_001624"
     CDS             complement(1059..2162)
                     /locus_tag="OPY25_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCS0927259.1"
                     /translation="MALTEPDFIERDADKITAEMIAKYEADTGKTLYPAQAERLLIDL
                     WAYREMLVRVAVQEAAKQNLVAFSREPMIDYLGELVDVYRLAAQPATTTLQFSVDEAL
                     AIDVLIPAGTRVSASDSIIFATDTDVVLKAGLLLVNVTATCTEPGTAGNGWQPAQVSQ
                     LLDEIDNIDLLVTNLTASSGGSEQEDDDRLRERIRLAPESFTNAGSRGAYRFHAMGAH
                     PGIVDVAVLSPAPGTVELYPLLSTGLPDSSILTLVESFCSDEKVRPLTDTVRAKTPVQ
                     VDYTIEARITIYRDQDARLVKDNANSAIQNWVASRTATLGRDIVPSQIISVLSVSGVY
                     QVELVTPALRVVAENEWANCTAITLNMTGVSDG"
     gene            complement(2153..2500)
                     /locus_tag="OPY25_001625"
     CDS             complement(2153..2500)
                     /locus_tag="OPY25_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HCS0927260.1"
                     /translation="MKTTSVFWQPALQAPGEIVRGLDDIRQSIQIILRTPRGSDPHRP
                     EFGSNLHLYIDWPVGRAIPHVVRESVDAIRRWEPRCQLMSVKPAVDGEHLTLRVSWKG
                     SDGQPRTQELLWR"
     gene            complement(2557..3084)
                     /locus_tag="OPY25_001626"
     CDS             complement(2557..3084)
                     /locus_tag="OPY25_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HCS0927261.1"
                     /translation="MTGVTRQIGTVSAVDADRVQARVRLPECDNLRTNWLNVLQRNTQ
                     DNKDYWLPDVGEQVEVLLDANGEDGVILGAVYSDVDKPPFSDKNVRGTKYADGAEFSY
                     NRATHTLTVRGGIERIVVEVAADISLKGKNLDLTGVTTINGPATLNGDLEINGSAHAT
                     GNIFADGQNSNHHSH"
     gene            complement(3081..4235)
                     /locus_tag="OPY25_001627"
     CDS             complement(3081..4235)
                     /locus_tag="OPY25_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HCS0927262.1"
                     /translation="MAEINSTAQATSALTSVSDVLTPVFTLWYLQKNITSDIAPYVTR
                     VVWSDNIKNESDTIEVELDDTDGRWLDKWYPGKGDTLTLKMGYQGEKLLSCGTFSIDE
                     IEVSSPASVVAIRGVATSVNSALRTKSSRGFENTTLAAVAGRIARKHRLKLVGSIESI
                     KIDRVTQYAETDVGFLRRLASEYGYAVKVVSDQLIFSHLATLRSQEPVRQLKPQGVAR
                     FSLRDTINRVYKSAKVKHQKSSSKKLIVYEADGGTRESDKKLKGGKVTSADSLKVNSR
                     VSDPDSARIKADSALARHNEYQQNGSLTLTGTPQLTAGNKIELVGFGQLSGPWLIITA
                     RHAFERNSGYTTELEVARGPVTRGKKQKTQKLTVYHPDGSTSTVIKEKKK"
     gene            complement(4223..4435)
                     /locus_tag="OPY25_001628"
     CDS             complement(4223..4435)
                     /locus_tag="OPY25_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HCS0927263.1"
                     /translation="MFLEHITRDGERWDSLAWQYYGDPLGYPRIIAANPHVAITPVLP
                     SGLLLLIPVIEAEDARTEEDIAPWLR"
     gene            complement(4435..5319)
                     /locus_tag="OPY25_001629"
     CDS             complement(4435..5319)
                     /locus_tag="OPY25_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001423226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0927264.1"
                     /translation="MFAVLGDIEFELITYWDGFEATFGVDYAEHARIEGKPGLQFVGD
                     RLDEIQISLVFHQHYCVPDVELARVRTAMKAHQALALVFGNGDYRGWFVITDVTATSE
                     QTDSTGNVLAVSATVSLREYTGDPKNPLQPPAIRRQVPGAGAVSGAVPSPSGVAQFVR
                     NGVNYAKQAQSVLQTTISAVRVAQKMKGNPVVALTRVPGLMSGLGNISGALGKSVPAF
                     NALSESMPDAISLARTASEAATYVQQAQSALSGVDKRNIAGALDTVSGQLNAAGTAFN
                     RMSPGLSAMAARILTRSV"
     gene            complement(5319..7784)
                     /locus_tag="OPY25_001630"
     CDS             complement(5319..7784)
                     /locus_tag="OPY25_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCS0927265.1"
                     /translation="MASEFSVGVIIGGIVGSSFRSAVSGTRRALDSLGDTSRRLQERQ
                     NALTRATERYGQLGSSRMQHLNSELLRVSRTMEQIERQQRRLSAVSATGDALKANRLA
                     LYGQGAETYAIGRTLGAPVMASVKQYASFESQLRDISVTGDLDAKQERAIGQAIRQAS
                     LKVNQLQESLLGGVGQLVADGMAPERAATFAEMLGKTATATKADMTDLAKMTYAFSDA
                     LRITDAKELEQAFGIAATGAKLGSFELKDMAKALPGMAKAFAARGIYGKDAITQIVAS
                     LEVGKGSGSAEEAVTNMSNWLAAMGRGDTIQKYAKAGVDYQGSMQNYVAQGFSQYEAS
                     LMIANRFIDSKGKAFLQQWKAAGARGDQEGQQKLMESFGLAEVFTDIQTVNHLLSMRQ
                     GWDKYLSSKQEMNAPAAISTLDKDAAKQNDTLEGRWRRMQIGFNDSAISIGQSLRPAL
                     LQLGETFIPLMDSVGKWIAANPQLVSSTIKVVGALLAFRMATIGLKLGLNLLLSPFVS
                     VWKNAVLLRANWLRLTLALGEGGKLRWLVTGFGAVARGARTLGGVLSGGLVRGIMSAG
                     RAVLWIGRALLMNPIGLVITAVAAAAYLIYRNWGAVSSWFKQRWADIQEAFNGGIVGI
                     GKLLVNWSPAGLLYKAFAAALKYLGVDLPAKFTDFGGHLIDGLINGIRNKWASLKTSV
                     TGMGDSISDWFSEKLGIHSPSRVFMGFGDNIAQGAAIGLQRTTPLAALAGQRLAAEMT
                     PDVPRIPSPEIMAAGYSGRGATATGGGASGGIKVSFNPQFFLNGKETAAPAGLTGALN
                     MSLHELEKMLERLLAQKQRKEYS"
     gene            complement(7878..8015)
                     /locus_tag="OPY25_001631"
     CDS             complement(7878..8015)
                     /locus_tag="OPY25_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HCS0927266.1"
                     /translation="MQAQGLLARWFRFQPGEIDALDTDDLEMWLEQAEEQIKSEFGDN
                     Q"
     gene            complement(7960..8295)
                     /locus_tag="OPY25_001632"
     CDS             complement(7960..8295)
                     /locus_tag="OPY25_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HCS0927267.1"
                     /translation="MSQTQSDTFTLSYPFTTAAGTRIEQIELKRLTVKDLKQVRKINK
                     DPADWDEPLIARSTGILPEDLDNMDLADYMELQKRFQKITGLGKSDKNTDAGAGPAGE
                     MVQVSTGGD"
     gene            complement(8393..8674)
                     /locus_tag="OPY25_001633"
     CDS             complement(8393..8674)
                     /locus_tag="OPY25_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927268.1"
                     /translation="MSVELTDKGGRCASLGMSNGTWFTLLDIPGVETLFNTRKTNDPI
                     DCTRSKARKLADLIEAWKPPDQWFSGTGKSEGKALLIAFLRNCKGFRTC"
     gene            complement(8677..9201)
                     /locus_tag="OPY25_001634"
     CDS             complement(8677..9201)
                     /locus_tag="OPY25_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HCS0927269.1"
                     /translation="MMSKIEINRITNANIYLDGTNLLGRAEEVKLPDVSMIMQEHKAL
                     GMVGKVELPAGFDKLEGEIKWNSFYRDAMLSAANPYKSLALQCRSSVQRYSSQGLIDE
                     IPLVTFLTIMFKKNPLGTFKQHENAEFSSSFTCTYIRQVLDGEELLQLDYLANIFRVG
                     GVDQLTDYRINIGG"
     gene            complement(9198..10625)
                     /locus_tag="OPY25_001635"
     CDS             complement(9198..10625)
                     /locus_tag="OPY25_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HCS0927270.1"
                     /translation="MAANYLHGVETIEVENGARPVKTVKSAVIGLIGTAPMGDVNTLV
                     QCLSEKDAAAFGSQFTGFIIPQALDAIYDHGAGTVLVINVLDPSVHKIAVVSENVSFD
                     KATGRARLANPVVAQLVLKPDSNGQPYVEGQDYSLDAQTGVITNLGKSIAADATVKAS
                     YNYADPTKVTPADIIGTVNAAGNRTGMKLLNDSFNLFGYFAKILIAPVFCTQNSVSVE
                     LIAMAEKLGAVTYIDAPVGTTFAQALAGRGPEGTINFNTSSDRVRLCYPHVKVYDPVT
                     NTERLEPLSQRAAGLRAKVDLDKGYWWSSSNQEILGITGVERQLSAMIDDPQSEVNLL
                     NEQGITTVFSSYGSGLHLWGNRTAAWPTVTHMRNFENVRRTGDVINESIRYFSQQYID
                     MPITQALIDALTESVNAYGRKMTGDGAVLGFRCWFDPARNPETELAAGHLLLSYKYTP
                     PPPLERLTFETEITSEYLLTLKGGN"
     gene            complement(10615..10866)
                     /locus_tag="OPY25_001636"
     CDS             complement(10615..10866)
                     /locus_tag="OPY25_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927271.1"
                     /translation="MKEYRYSGPASGVTLSDGTEILLWPGKTVSLPEEHDYVKVLVAL
                     KHLTPVPEDTKPAVTPAVQSPKRRSSSDSEVKTEDSHGS"
     gene            complement(10866..11330)
                     /locus_tag="OPY25_001637"
     CDS             complement(10866..11330)
                     /locus_tag="OPY25_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gp37 family protein"
                     /protein_id="HCS0927272.1"
                     /translation="MNVLPVLDAVLARLREKLPQLQVEYFPEKPAEYRLNHPVGALLL
                     SYAGSRFDRPDDTGAVIQSQTIQLCVTVVFRQLNGKKGAINVLDAVRRILGGHTPPGC
                     RRRIWLTREVFIGEVRGLWQYALDFATESVFIEDSDLPSGPLLTEVNYEESE"
     gene            complement(11330..11776)
                     /locus_tag="OPY25_001638"
     CDS             complement(11330..11776)
                     /locus_tag="OPY25_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1320 domain-containing protein"
                     /protein_id="HCS0927273.1"
                     /translation="MYCTLEDLLAQVPERTLIELTSEEMDFDSPATVNTRVVDSCIRY
                     ADELIDAHLRGRYILPLAEIPTVLRDIAITLVRYRLYARRPEGDLPDTVKDDHKEALR
                     QLRELRDNRLTLGLPSTQKDVPEPGEFRVRSRPATFGGRDGLLEKY"
     gene            complement(11778..12116)
                     /locus_tag="OPY25_001639"
     CDS             complement(11778..12116)
                     /locus_tag="OPY25_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HCS0927274.1"
                     /translation="MGTTQQVILITTVTAGAALAQQRFVGADNTPCKAGAAALGVAEV
                     DAVTGDSTPVSVLGIIAVEAGAAVSRGVAVQSDAQARAVPQSGDGKSCGIALDEAGGE
                     GDVIRILRGV"
     gene            complement(12126..13079)
                     /locus_tag="OPY25_001640"
     CDS             complement(12126..13079)
                     /locus_tag="OPY25_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927275.1"
                     /translation="MSDYLKGKRVVDPVLTSIARGYKNAAFIGERIFPVVLTDKEGVR
                     VPTFGKTAFVEYDTERAVGADSNVLVREKTGTLDLVLGEHDLAAPVDYREQAESMFNE
                     ESKAIRRATNGVNLRRELIAARLAQDEKVYRTGHVKKLTAGDRWAGGKGDPIGVIEAG
                     MEAVRTATGLRPNLMTMGAGVMALLKFHPAIQAAIGANERKRITTEILQDLFQIEEIV
                     IGAPVSLPSMKAAMDKDSVPTDIWGDNLMLHYVGKPQPGADSADENEPSFGYTLRRKG
                     MPVADKYDGAGGKVKYCRYTDIYKVAVVGGDAGYLITGISK"
     gene            complement(13094..14209)
                     /locus_tag="OPY25_001641"
     CDS             complement(13094..14209)
                     /locus_tag="OPY25_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCS0927276.1"
                     /translation="MSAIHIFKAGTHTDMHGKKLPFTPDDLAACVKAYDPSVHEAPLV
                     IGHPRTEDPAWGWVKALSLSGVDLMAEPAQLDPQFAEMVTDGRFKKVSASFYLPDSPS
                     NPKPGVLYLRHVGFLGAQPPSVKGLKQVSFSEQEEGVVEFADWQAITNASLWGKLRDF
                     LIARFSLDEAEKVLPEWQLNSLREEAYRDTLSQDAAGAQFSETGPGPSSASNEESSMT
                     KEEIEALQEENRRLKQQAADRDARDAQVRQEQLHKDNVAFAEKLVAEGRLAPRASSVV
                     VALLDAVAGGDKPVEFAEGESRTPLATAFRSLLSDGEPVMNFAEQATKDRVGDAVKVD
                     VAEFAEADPERLALHQKAVALSKKEGISYEAAVARCL"
     gene            complement(14424..14882)
                     /locus_tag="OPY25_001642"
     CDS             complement(14424..14882)
                     /locus_tag="OPY25_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000135514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HCS0927277.1"
                     /translation="MASDNLVSITINDKSLRRSLRALDLAATDMEPAMRKIAGTLLAE
                     TQFNFLDEGRPGWMPSLAAEERDGQTLQDTGRLMGSVSTDHDDRQAVVGTNVVYGAIH
                     QFGGKTGRNESVELPARPFLPVTGDGELQPEVVIPILDTIVRHLESAARR"
     gene            complement(14885..15706)
                     /locus_tag="OPY25_001643"
     CDS             complement(14885..15706)
                     /locus_tag="OPY25_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCS0927278.1"
                     /translation="MSVTTAELAYCMTLPPKRAVSYLKSKGYQITWDWEEMWQEAHAR
                     AFTVAKVTRLDILEDIRGALQQAVDEGKTDRWFRQELEPVLKRKGWWGPRDTTDPVTG
                     KPVTIQQGSPWRLDTIFRTNMSVLYSAGRWAEQMENVDDRPYWMYTGINDSHTRRSHL
                     ALHGLVLRWDDPFWQAFYPPNGWRCRCSVIALSATDVRARGLKVISSGSAMGQELKLV
                     SEKTGEMRNVATFNTGTTKVTTDVGWSYAPGAAYRPDLARYQGTLQPLAQQELRG"
     gene            complement(15687..17183)
                     /locus_tag="OPY25_001644"
     CDS             complement(15687..17183)
                     /locus_tag="OPY25_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF935 domain-containing protein"
                     /protein_id="HCS0927279.1"
                     /translation="MARGIWVSPDEFVAFSEPQKSLTAQIASRSRAIDFYGLGMYLPN
                     PDPILKAQGRDIRIYRELRTDPLVGGCIRRRKAALKSLERGLERGHASARVFRFIRDM
                     LDDLDLSRIIGEMSDAVLYGYQPCEIMWGRSVRAWAVTDIVGKPPEWFQFDTDNCLRF
                     RARDAGVEGELLSPSKFVVPAQDASYDNPYGFPDLSMCFWPVAFKKGGMKFWLRFAEK
                     FGSPWVIGKHPRGANDAEIEKLLDSMEQMVEDAVAAIPDDSSIELKAADGKADSSEVF
                     RELITLSRSEISIALLGQNQTTEANSNKASAQAGLEVTADIRDADADIIQAAVNQVIR
                     TVVTLNFGDVPCPVWAMWEQETIDDTRATRDEKLTRAGLRLTPQYFKREYQLQDGDID
                     ETPPSERQNNMLPLSFAEAIDADIQAQQQLDDALDILMNGGVLNGTLEPVLAPLFKRV
                     ENGVNPTELLGELAELYPQMNTDDLQERLARILFVANIWGRLHERDNG"
     gene            complement(17183..18724)
                     /locus_tag="OPY25_001645"
     CDS             complement(17183..18724)
                     /locus_tag="OPY25_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927280.1"
                     /translation="MSPMDGRNNLAPVLPDTSALDAPPVLLPYQQRWVADTSPLKVIE
                     KSRRTGITWAEASDNVLTAASSAPAGGMNVYYIAYNQDMTVEYIQACAMWARAFNYAA
                     SEIEEGFWEEDDDDKHIKTYTIKFPDSGFRIVALSSRPSNLRGRQGIIVIDEAAFHEQ
                     LDELLKAALAMLIWGGKVRVISTHDGDDNPFNTLIGDIRAGRQGGSVHRITFREAVSE
                     GLFRRVCLRTGKEWSEASEQAWMASVYKFYAAGASEELDCIPANGGGAWLSRALIESR
                     MSADTPVLRLTCQEGYELLSDEVRFHETQDWLDEHLKPLLEALPADARSFLGRDFGRS
                     GDLSVDYPLLQEKNLVRRVPFVLELRNVPFRQQEQITWYLMDGLPGLLGAAFDARGNG
                     AYLAEYAMQRYGSSRVQQVMPTEGWYREHMPPVKAALEDGNLVDLPKDEDTLDDLRAV
                     QVVNGVPRVPEQRSKAKADGGKRHGDSAIALALAYFASREINKGPVKASSRCRRQAAR
                     MLEGF"
     gene            complement(18775..19320)
                     /locus_tag="OPY25_001646"
     CDS             complement(18775..19320)
                     /locus_tag="OPY25_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3486 family protein"
                     /protein_id="HCS0927281.1"
                     /translation="MARRSTIEKLPEDVRRWLERALTESGFSGYNELESLLRERGYVI
                     SKSAIHRYGQKIERRYGAIRAATEAARMLTEGAADDQDARSEAVIALIQTELFESIVQ
                     LQEAEEGEVDPKERVALLSKVAKNVATLSRASVNLKKFQSEVRARAQQAASNAEKIAR
                     KGGLSSDAVQALRREILGIAT"
     gene            complement(19320..19631)
                     /locus_tag="OPY25_001647"
     CDS             complement(19320..19631)
                     /locus_tag="OPY25_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927282.1"
                     /translation="MVDITRVRRESLRWSLLVALNKTRPYTASETLLLDVSRAIYPDT
                     TPLELRRELDYLADRKMVDLEKKPSGDWFADLTRLGVDLVEYTVECGPGIARPEKYWS
                     E"
     gene            complement(19631..19957)
                     /locus_tag="OPY25_001648"
     CDS             complement(19631..19957)
                     /locus_tag="OPY25_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927283.1"
                     /translation="MTLQVEFWTVVSFLLTFMGFVGGLAKWLFSKTEERQAARFASLE
                     QALQQSASNWGELEKEFMRFKADLPLNYVRREDYIRGQTVIEAKLDALYNKLEVVQQY
                     RNTGGQ"
     gene            complement(19954..20604)
                     /locus_tag="OPY25_001649"
     CDS             complement(19954..20604)
                     /locus_tag="OPY25_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000264665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0927284.1"
                     /translation="MWHLVKKLPWRGILLAILINAFLVGLYAMGYRSGHDSAKRDGDT
                     ALSQLQSAFDAYKTEQATLENAALRAWARRYQEQVAAGQRAEAGYLEQIAQLESRNKQ
                     LQGQINDVTQRWIDEKGKSHPIECVFTRGFVRQYNAALGYDNASVDTGHSDSVAAAGT
                     RSGTATGQPETTDTRLRDSGVSQRDVLANIIDNAGQCRRWRNQINALLDEREGLQK"
     gene            complement(20588..21316)
                     /locus_tag="OPY25_001650"
     CDS             complement(20588..21316)
                     /locus_tag="OPY25_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HCS0927285.1"
                     /translation="MNWPQITLIILFAFGLGVTAIRHGEPRNDKYSFWWQLAGNLVIV
                     WLLWCGGFFSQARAAQPPQAALQYRDDVIRNARLEWGLSAPVADFAAQLHQESGWRPD
                     VVSPAGAQGLAQFMPATADWISQLIPMLSNREPFNPAWAIRALVSYDRWLWQRVSAAN
                     DCERMAMTLSGYNGGLGWVQRDRRLASQKGLDSTRWFGHVATVNAGRNAASWRENRHY
                     PQRILRELAPRYLTWGGCSCVASG"
     gene            complement(21319..21669)
                     /locus_tag="OPY25_001651"
     CDS             complement(21319..21669)
                     /locus_tag="OPY25_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin"
                     /protein_id="HCS0927286.1"
                     /translation="MKNLKKFIPPVKKPRLSGWLLTSVLLLGIIALVSPQQLPVVIYK
                     LALITLAAVLGYWLDRSLFPKARPGQYLKHDDRLMAEGRFPVQTGLHLVFSAALIRRA
                     LIVAAVCLAVATGL"
     gene            complement(21913..22509)
                     /locus_tag="OPY25_001652"
     CDS             complement(21913..22509)
                     /locus_tag="OPY25_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCS0927287.1"
                     /translation="MILTDVRYASPNSLSNGDASERLSPEEGLVTEASQRLINDICAK
                     YAGRTQFLGCNDVLIAKRESEKLRDVLKAFAAEKGLDGAEKDAFLKSAFEHLHALSKA
                     GEPLSLETLVNAIWPQAPEELSGKLAAEELELSDGFVPDGRVIRALVSFKGKSKYWEL
                     KFDREGKTEGYIDYDPETNIITLRNVPEEFREMWMTEV"
     gene            22553..22936
                     /locus_tag="OPY25_001653"
     CDS             22553..22936
                     /locus_tag="OPY25_001653"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927288.1"
                     /translation="MPTLAHLGKAKLFELMTEDDEELAELADGGTVAGLTLDDVDRMS
                     VRELRQALREARETNAAQQRVLADKNEKIDSLSTRLEKKSRIQPPEPDEEVKKLRAEV
                     TALAVEAESAIAVRLSSAFETLCAY"
     gene            22946..23110
                     /locus_tag="OPY25_001654"
     CDS             22946..23110
                     /locus_tag="OPY25_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927289.1"
                     /translation="MIDTPRDFMAGLVCQLESTARSLRSTFDLPDEPTGNAAPSWLTE
                     PTPQINGLEA"
     gene            23114..24883
                     /locus_tag="OPY25_001655"
     CDS             23114..24883
                     /locus_tag="OPY25_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HCS0927290.1"
                     /translation="MNAALTERLVYVARAARDAGHGKRGAIYDAACAELGMSRATLLR
                     RLKEVSVTDKRKKRADAGRSALTRDEAALISATLREATRKNGKRLYSIADAVETLRAN
                     GFISAGRTDETTGEFFPLSEDAISRALRNYGLHPEQLDAPAPYTEVASLHPNHVWQID
                     ASLCTLYYLSNGHKGLQVMDSAKFYKNKPANLARIASDRVWSYEITDHASGWIYVEYV
                     TGAESGENLCSVLINAMQERGGADVLHGVPKILYLDPGSANTAGMTKNMCRSLGIDLI
                     AHKPHNARATGQVEKARDIIERKLEPGLKFRPVHSLEELNALAAKWRSHFNATAVHSR
                     HGKTRTDIWLKITAEQLKKAPSVEVCRELAVAAPELRKVTPKLRVSFRGTEFDVSTVP
                     GVLVGEKLMITRNPWRSDVAQVVLTGEDGHETFFLVEEVRKNEFGFAEGAAVFGESYK
                     ALPETPAQMAAKETEALVTGTDNAADAAAARKAKALPFGGRLDPYKHIDDATLPACIP
                     KRGQASDVRGPRTEQRPMTHVEAAKALRGKFSANGLTWTPEHYRQLTAQYPDGVPEAA
                     LDEVMATLTTPARSSVISIVNGN"
     gene            24894..26060
                     /locus_tag="OPY25_001656"
     CDS             24894..26060
                     /locus_tag="OPY25_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCS0927291.1"
                     /translation="MLVLKQQLKEARIPQAVVARAVDVSEATLAQIVNHNAWPRTSPG
                     EVRRRLASWLESQGIDTAKSFDAVQGAATPRTAGTTDKTSLSEEENMLLKKQVLFPAT
                     KKAFGLFRDPFADEAMQGSDDVFTTPDIRYVREALYQTARHGGFMAVIGESGAGKSTL
                     RRDLTERINRENAPVIVIEPYIIAMEDNDVKGKTLKAAAIAEAIISTIAPLESIRRSQ
                     DARFRQLHRVLKDSNQAGFSHVLVIEEAHSLPIPTLKHLKRFFELESGFKKLLSIVLI
                     GQPELATKLSERNMEVREVVQRCEVVELLPLDNHLEEFLTFKLQRAGKQLTDIMDASA
                     VDAIRTRLSNPGSHRKNMVSLLYPLAVSNLVIAAMNLAAEIGVPQVNADVVKGV"
     gene            26063..26332
                     /locus_tag="OPY25_001657"
     CDS             26063..26332
                     /locus_tag="OPY25_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927292.1"
                     /translation="MKSTTGINQQISKVQSAIMALKATNTDVQSITIRGNKPVIRVSR
                     SAHCMRMLEQGKACYLYTGHDHRGYFRQGVFELHGCRVVWPESLW"
     gene            26360..26890
                     /locus_tag="OPY25_001658"
     CDS             26360..26890
                     /locus_tag="OPY25_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="HCS0927293.1"
                     /translation="MAKSTKGAKRIKAAAALWVPGTREEVIEGIRLLGDAHRELVRAE
                     TEMNDAIGDITARYAPLTESLKKRMAELQSGIQTWCEAHRDELTGNGKVKFANLTTGE
                     VQWRNRPPSVSIRGADNVIELLRRLGLERFIRVKEEINKDAILNEKEAVKNIPGISIK
                     SDIEDFSIIPFEQDVQ"
     gene            27179..27451
                     /locus_tag="OPY25_001659"
     CDS             27179..27451
                     /locus_tag="OPY25_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927294.1"
                     /translation="MITPQEARQRTRALVEHYVNECECRDLTDVKHVLTALISMATQA
                     IVATNGKAAALQVLVNTLTHTAENEVPYRMETTAEGGLHITVSRKH"
     gene            27461..27763
                     /locus_tag="OPY25_001660"
     CDS             27461..27763
                     /locus_tag="OPY25_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927295.1"
                     /translation="MTRNTELTRTALYRLALQRFGPDAQALKLTEEAAELAASAARNL
                     NGQGSESDLAAELADVEIMTEQLRLQGMDRLIDFHKQKKLERLAARLGVTYTGEII"
     gene            27760..28143
                     /locus_tag="OPY25_001661"
     CDS             27760..28143
                     /locus_tag="OPY25_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001315283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927296.1"
                     /translation="MNRTEQTPQLTPEDAAQRIRVLEDENEYLRKRFEEVDLYFGRNL
                     VVMKAAVIEWRATGDARNGMAWIYNTLCGPGELPPQEEKEAQEYFNRETEVIDRKLAA
                     LYHWFRKYHRTHAAPDQTTTGGTSD"
     gene            28151..28351
                     /locus_tag="OPY25_001662"
     CDS             28151..28351
                     /locus_tag="OPY25_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927297.1"
                     /translation="MEIVVWAFLLTGIAVCICAGFALVALLTHVVTQWLWEKLKAAYS
                     LKELSDAVRAWEQQKNTGDTEQ"
     gene            28348..29031
                     /locus_tag="OPY25_001663"
     CDS             28348..29031
                     /locus_tag="OPY25_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HCS0927298.1"
                     /translation="MTDQDKHIEKLKKLLALAASGNPHEAALALRRARKLMDVHGITH
                     SDIAMSDIDETISHYWPTGSLRPPRYMLGLMNIIREAFGVNSIIHPGTYPGVGFYGNR
                     ERAALAAYTWEVLARQLKKARQQYISAQNKRIKTATRTSRGDQFAEGWVLAVISEIQS
                     FALTDDERELMQQWLEHKYPQTQTTRARKPGRSRNGDASRYAGFREGQNVRLHRPVSG
                     REQQKLEAR"
     gene            29028..29258
                     /locus_tag="OPY25_001664"
     CDS             29028..29258
                     /locus_tag="OPY25_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927299.1"
                     /translation="MITLSGNSRKLKACRISARYLFARAFFKNVRPGITIGVIAGREQ
                     VEKYMSGAWWNKDPVIAARNIHISWGDIQNDD"
     gene            29248..29463
                     /locus_tag="OPY25_001665"
     CDS             29248..29463
                     /locus_tag="OPY25_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927300.1"
                     /translation="MTTESVVCALFWYCFVGWCTAELHRRSGFYSRYSGAGYWISWSV
                     MFLCWPVALPLYVDYIGDAGRRSNNDD"
     gene            29456..29905
                     /locus_tag="OPY25_001666"
     CDS             29456..29905
                     /locus_tag="OPY25_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein GemA"
                     /protein_id="HCS0927301.1"
                     /translation="MTKQRLIQLIHIARNELGMDEDTYRQMLQGLTGKASTKGMDTTQ
                     LNCVLESMKRKGFRVRPAGKASSGLPLDNHPQSRKIRALWLEMAAAGIVRDRSENALA
                     RWIKRETGISALRWLNTEQASSVIEKLKKWQRRAAGVKHERPESVSK"
     gene            29877..30266
                     /locus_tag="OPY25_001667"
     CDS             29877..30266
                     /locus_tag="OPY25_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCS0927302.1"
                     /translation="MSDLNQFRSKGPELLVELAQHTSETVREIIDIEPAIADQIGQAV
                     ANRMMQVWGGQNVYFPMGMVWKVSQRDREIFREFNGRNHHELARKFGVSLQWVYSVVK
                     RVRKEELDRMQGKLFADEPDVDTEKKE"
     gene            complement(30448..31392)
                     /locus_tag="OPY25_001668"
     CDS             complement(30448..31392)
                     /locus_tag="OPY25_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0927303.1"
                     /translation="MKLKNTLLASALLSAAAFSVHAATELTPEQAAALKPYDRIVITG
                     RFNAIGDAVSAVSRRADKEGAASFYVVDTSEFGNSGNWRVVADVYKADAPKADAPKNR
                     VINGIVELPKDQAVQLEPYDTVTVQGFYRSQPEVNDAITKAAKQKGAYAFYIVRQIDA
                     NQGGNQRITVFIYKQDAKKRIVQSPDAIPADSEAGRAALAQGGEAAKKVEIPGVATSA
                     SPSAEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSVKFTGNYGNMTE
                     ISYQVAKRAAKKGAKYYHITRQWQERGNNITISADLYK"
     gene            31919..33448
                     /gene="pntA"
                     /locus_tag="OPY25_001669"
     CDS             31919..33448
                     /gene="pntA"
                     /locus_tag="OPY25_001669"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HCS0927304.1"
                     /translation="MRIGIPKERLPNETRVAATPKTVEQLLKLGFSVAIESGAGQLAS
                     FDDKAFAQAGADIVDGNAIWQSEIILKVNAPEEEEIALLNPGTTLVSFIWPAQNPGLM
                     EKLAERKVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSEAFIKAEMALFAAQAKEVDIIVTTALIPGKPAPKLITRDMVDSMK
                     AGSVIVDLAAQNGGNCEYTVANQVVTTDNGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNIDVDFDDVVIRGVTVIRDGDITWPAPPIQVSAQPQAAPKAAPAPKEP
                     EKPASPWRKYALMALAIILFGWLADVAPKEFLGHFTVFALACVVGYYVVWNVSHALHT
                     PLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFRK
                     N"
     gene            33459..34847
                     /gene="pntB"
                     /locus_tag="OPY25_001670"
     CDS             33459..34847
                     /gene="pntB"
                     /locus_tag="OPY25_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HCS0927305.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LLATIFGPDTGNVAWILVAMIIGGAIGIRMAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLYHDASLAPVLVNIHLTEVFLGIFIGAVTFTGSIVAFGKLRGKISSKPLMLPNR
                     HKMNLAALVVSFLLLLVFVRTESVGLQVLALLLMTIIALAFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEAGEHREITAEETAEMLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPRSPIAGMPVLEVWKAQNVVVFKRSMNTGYAGVQNPLFFKENTQMLFGD
                     AKASVDAILKAL"
     gene            complement(35022..36056)
                     /locus_tag="OPY25_001671"
     CDS             complement(35022..36056)
                     /locus_tag="OPY25_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCS0927306.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVVILSGIRFAADIIVPFILALFIA
                     VVLNPVVQRMTRCRIPRVIAVSLLIVIIVMLMVLLLAYLGTSLNELARTLPQYRSSLV
                     IPLQRIEPWLQRAGIGVSVDELAKYIDPNAAMTLVTNLLTQLSNAMSSIFLLLLTVVF
                     MLLEVPQLPEKLQQMMSRPVEGMAAIQRALDSVSHYLVLKTAISIVTGLVAWGMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAALPPIIQVLVFNGFYDALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTTGGQSI
                     AVLLSDLNKR"
     gene            36473..36835
                     /gene="mdtJ"
                     /locus_tag="OPY25_001672"
     CDS             36473..36835
                     /gene="mdtJ"
                     /locus_tag="OPY25_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HCS0927307.1"
                     /translation="MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSY
                     IFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIK
                     SGTRKPGKPVKEATRATI"
     gene            36822..37151
                     /gene="mdtI"
                     /locus_tag="OPY25_001673"
     CDS             36822..37151
                     /gene="mdtI"
                     /locus_tag="OPY25_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HCS0927308.1"
                     /translation="MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAG
                     MVMIKFA"
     gene            complement(37186..38007)
                     /locus_tag="OPY25_001674"
     CDS             complement(37186..38007)
                     /locus_tag="OPY25_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HCS0927309.1"
                     /translation="MHKTIAVLLGIVCFLPVMAKAGGAETDATDASDVKTLFFNHDDR
                     VPVADPTQSPWDAIGQLETASGNLCTATLISPHIALTAGHCLLTPPKGKPDKAVALRF
                     VARKGVWRYEIHGIEGRVEPSLGRRLKADGDGWIVPPAAASWDFGLVILRYPPSGITP
                     VPLFTGDKAALTAALKAADRKVTQSGYPEDHLNALYSHQDCVVTGWAQNAVLSHQCDT
                     LPGDSGSPLLLHTDSGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLKALAQD"
     gene            complement(38276..38527)
                     /locus_tag="OPY25_001675"
     CDS             complement(38276..38527)
                     /locus_tag="OPY25_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001698353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HCS0927310.1"
                     /translation="MKKVLALVVAAAMGLSSAAFAAETATPAKTAAPAKTTQTTQHHK
                     KQHKKTVEQKAQAAKKHQKKDGKKAPAKSTSKTTSQPAA"
BASE COUNT         8759 a        10748 c        10537 g         8864 t
ORIGIN      
        1 tttttgacaa acagcgcagg ctcaggaata tctgcgccgt tctggtcttt agccagcttt
       61 tccgccagct tgttcagtac cgtagtcgca aagtttggat cattaccgag agcgtcagcc
      121 agctctttaa gcgtatccag tgtctcaggg gcgctgcctg caagtgccgc aagtgctttg
      181 gccacaaact ccgtcgtcgc cagctttttg ctgttatcac catttgcagg tgtaggtgct
      241 gttggtgtgc cggtgaatgt cggactggct ttcgtcgcgt actgggtatg cgggtcaact
      301 gccgcgatat gtgcagccag gtctgttccg cttttttcga ccttctgttt gaggtatgac
      361 gttcggctgg ccagttgttt agcctggcgg ttagaaattc cgtcaggtcc gcccagaacg
      421 gggtcagaga cctcaatctg gtagatgccg ctttcccact gcggggtttc gggtagattt
      481 gccataatta actgctcccg tggttgtaac taccgtcata acgggtagta ctgttgtatc
      541 gaatggcgac agactgatat tccagacttg ccagatgaca gcgagccgga gcaaaggcag
      601 caagcgtctg acgtaacagc gccgcctgat cgttagtgat gggttgttga aggatgacgc
      661 gatagactgc ccaggcttgt gcatcaccat ggacgaaaag cccgttgtac gtgtgtctgc
      721 cgtcatagcc aatctgcccc gtaccttcaa tcagatccac ttcgccgaag ccaaaacggc
      781 ggataatttc ccggattgac cacggtgttc ctttatagcg gtgtagctcg atagcggatt
      841 tgataagcat gcggcgtaca tcgtccgatt ccgccagttc ccagccatcg ccgaacagcg
      901 agaactgctc gccaagccat ggcagcgcgg aactgtcgac aatatcgacg agaccgacca
      961 tcagtacgct caggtcgatg ttatccagcc gtccggccag tcttcccagc gttctgagac
     1021 tgatatcacc ctcaagcggt ggcgggagtt gtagcacctc agccatcgga caccccggtc
     1081 atgttaagag tgatcgctgt acagtttgcc cattcgtttt ctgccaccac cctcagtgcc
     1141 ggtgtcacca gttcgacctg gtacaccccg gaaacggaca acacgctgat aatctggctg
     1201 ggaacaatat cgcgccccag cgtggcggta cgggatgcca cccagttctg tatggcgctg
     1261 ttagcgttgt cctttaccaa ccttgcatcc tgatcacgat agatcgtaat cctggcttca
     1321 atggtgtaat ccacctgaac aggtgtttta gcccgcacgg tatcagtgag tggtctgact
     1381 ttttcgtcag aacagaaact ctctaccaga gtgaggatac tgctgtccgg cagaccagtg
     1441 ctgagcagcg gatacagctc gacagtgccg ggagcgggag aaagaacagc aacgtcgaca
     1501 atgccgggat gcgcccccat agcatgaaaa cggtatgcac cacggcttcc ggcattggtg
     1561 aatgactccg gggccagcct gatacgctcc cggagccggt catcgtcttc ctgctctgaa
     1621 ccgccagagc tggccgtcag attggtcacc agcaggtcaa tgttatcaat ctcatcgagt
     1681 aactgactga cctgcgccgg ttgccagccg ttgccagcgg tacccggctc ggtacaggtg
     1741 gccgtgacat tgaccagcag caatccggcc ttcagcacca catctgtatc ggtggcaaaa
     1801 ataatactgt cggaagcgct gacgcgggtg cctgccggga tcagcacatc aatggccagt
     1861 gcctcatcca cagagaactg aagtgtggtg gtggcaggct gcgcagcaag gcggtatacg
     1921 tcgaccagtt caccgaggta atcaatcatc ggctcacggg aaaaagcgac cagattctgc
     1981 ttcgccgcct cctgtactgc caccctgacc agcatttcgc gataggccca caggtcaatc
     2041 agcagacgtt cagcctgtgc cgggtacagc gtttttccgg tatccgcttc atacttcgca
     2101 atcatttctg ccgtgatttt atcggcatcg cgttcaataa aatcgggttc tgtcagcgcc
     2161 atagcagttc ctgagtacgg ggttgtccgt ctgagccttt ccagctcacc cggagcgtaa
     2221 gatgttcgcc gtcgacggcg ggtttaaccg acataagctg gcagcggggt tcccagcgcc
     2281 tgatggcatc gacggattcg cgaaccacat gcggaatggc ccggccgaca ggccagtcga
     2341 tataaaggtg cagattgctg ccgaactccg ggcgatgcgg gtcgctgccg cggggagtcc
     2401 gcaggatgat ctggatggac tgccggatat catccagccc ccggacgatt tcgccgggag
     2461 cctgcagagc tggttgccag aatactgagg tcgttttcat ggaggcagta ttgcccccgg
     2521 gaagtaagcg ccgatattaa aggcgtttaa gaaggttcaa tgggaatggt gattagagtt
     2581 ctgaccatca gcaaatatgt tacccgttgc atgggcgctt ccgttgattt ccagatcacc
     2641 attgagtgtc gcggggccgt tgatcgtggt aactcccgtg aggtcgaggt ttttcccttt
     2701 gagagagata tcagcggcaa cctccaccac gatacgctca atacctcctc tgaccgtcag
     2761 cgtatgggtc gcgcggttat aactgaactc cgcgccatca gcgtatttcg taccccggac
     2821 gtttttatca ctgaacggcg gtttatcgac gtctgagtac accgcgccca gaataacacc
     2881 atcctcgccg ttggcatcga gcagcacctc aacctgctcc cccacgtcag ggagccagta
     2941 atccttgtta tcctgggtat tgcgctgtag cacgttaagc cagtttgtgc gcagattatc
     3001 gcattcaggc agacgaacgc gggcctgaac cctgtcggca tcaacggcac tgaccgtacc
     3061 gatctgacgg gtgacaccag tcattttttc ttctccttaa tcaccgtcga tgtactgcca
     3121 tccgggtgat aaaccgtgag tttctgagtt ttttgttttt tccctcttgt gactggcccc
     3181 cgtgccactt ccagctctgt ggtgtagccg ctgttacgct caaacgcatg gcgggcagtg
     3241 attatcagcc atggaccgga taactgtcca aagcccacca gttcaatttt gttgcctgct
     3301 gtcagttgag gcgttcccgt cagcgtcagg gagccgttct gctggtattc gttatgtctg
     3361 gccagtgctg aatccgcttt aatccgggcg ctgtccgggt cgctgacgcg gctgttaact
     3421 ttaagtgagt cagcgctggt aaccttaccg cctttgagct ttttgtcgct ttcacgggta
     3481 ccaccatcag cttcgtagac gatcagtttt ttactgctgc ttttctggtg ttttaccttt
     3541 gcagatttat agacccggtt gatggtgtca cgcagggaaa agcgggccac accctgcggt
     3601 tttaactgcc tgaccggctc ctgactgcgc agtgtggcca gatgagaaaa aatcaactgg
     3661 tcactgacca ctttcactgc ataaccatac tcgctggcca gccggcgcag aaaacccacg
     3721 tcggtttcag catactgggt cacccggtcg attttgatgg actcaatgct gcccaccagt
     3781 ttcagtcggt gctttctggc aatccgcccc gcaacagctg ccagcgtggt gttctcaaaa
     3841 ccacggctgg atttagtccg cagagcactg ttaaccgagg tggccacccc acggatagcg
     3901 acaacggacg cgggcgaact cacttcgatc tcgtctattg agaatgtacc gcaggacagc
     3961 agtttctcgc cctgataacc cattttcagc gtcagcgtgt cacccttgcc cggataccac
     4021 ttatccagcc agcgaccatc ggtgtcatcc agctccacct caatggtatc ggactcattt
     4081 ttgatgttat cgctccagac cacacgggtg acataaggcg cgatatcaga ggtgatgttt
     4141 ttctgcagat accacagagt gaataccggc gtcagcacat cgctgacgct ggttaacgct
     4201 gatgtggctt gcgcagtact gtttatctca gccatggggc aatatcctct tctgtacggg
     4261 catcttcagc ctcaataacc gggatcagta acaacaaccc ggagggcagc accggcgtaa
     4321 tggccacgtg cggattggct gcaataatcc ggggatagcc cagcgggtca ccgtagtact
     4381 gccatgccag cgaatcccag cgctctccgt cacgggtaat atgttcaaga aacatcacac
     4441 actcctcgtc agtattctgg cggccattgc acttaatccc ggagacatgc ggttgaatgc
     4501 tgtgccggcg gcgttaagct gcccggaaac ggtatccaga gcacctgcaa tatttctttt
     4561 gtccacacca ctcagcgccg actgcgcctg ctgtacatac gtggctgcct cactggctgt
     4621 tctggccaga ctgatggcat cgggcatgga ttcagagagt gcattaaacg ccggaacact
     4681 tttccccaga gctccggata tattacccag tccgctcatc agtcccggca cacgggtcag
     4741 cgcgacaacg gggttaccct tcattttctg cgccacccga acggcactga tagtggtctg
     4801 gagtacagac tgcgcctgtt tcgcatagtt gacgccgtta cggacgaact gcgccacccc
     4861 ggaaggcgat ggaacagcac ccgatacagc tccggcaccg ggaacctgcc tgcgtattgc
     4921 cggcggttgc agaggatttt tcgggtcacc ggtgtattcc cggagagaca cggtggcact
     4981 gacagccagc acgttaccgg tgctgtctgt ctgctcgctg gttgcggtca catcggtaat
     5041 cacgaaccag ccgcgatagt caccgttgcc gaagaccagc gccagtgcct gatgggcctt
     5101 catggctgtt cgcactctcg ccagctccac gtcgggcaca caataatgct gatggaagac
     5161 caggcttatc tggatttcgt ccagcctgtc gccgacaaac tgcaggccgg gtttaccctc
     5221 gatgcgggca tgctccgcat aatcgacgcc gaacgtggcc tcgaagccgt cccagtaggt
     5281 aatcagttca aactcaatat cacccagtac ggcaaacatc agctgtactc cttacgttgt
     5341 ttctgagcca gcagacgctc cagcattttt tccagctcat gcaggctcat attcagggca
     5401 ccagtcagcc cggcaggcgc tgcggtttcc ttaccattga ggaaaaactg aggattaaag
     5461 ctgaccttga taccgccaga cgctccaccg ccagttgcag ttgcgccacg gcctgaatat
     5521 ccggcagcca tgatttccgg cgacgggata cggggaacat ccggtgtcat ttcagcggcc
     5581 aggcgctgcc cggccagtgc agcaagcgga gtggtccgtt gcaggccaat ggcggcaccc
     5641 tgcgcgatat tgtcaccaaa gcccataaac acgcgactcg gtgaatggat gcccagcttt
     5701 tcgctgaacc agtcactgat gctgtcaccc attccggtta cgctggtttt gagtgacgcc
     5761 catttgtttc tgatgccatt tatcaacccg tcaataagat gaccaccgaa gtcggtgaat
     5821 ttcgccggca gatcaacgcc gagatatttc agcgcagccg caaaggcttt ataaagcaga
     5881 ccagccggag accagttaac cagcagttta ccaattccca cgatgccgcc gttaaaggct
     5941 tcctgaatgt cagcccagcg ctgtttaaac cagctactga ctgcgcccca gttgcggtag
     6001 ataaggtaag ctgctgccgc gacggcggtg ataacgagac cgatgggatt catcagcagc
     6061 gcccggccaa tccagagaac ggcacgcccg gcgctcataa ttccgcgaac cagcccccct
     6121 gagagcacac cacccagtgt tctggctcct ctggcgacag caccaaagcc tgtcaccagc
     6181 cagcggagtt taccgccttc ccccagtgcg agcgtcagac gaagccagtt ggcccgaagt
     6241 aaaacagcat ttttccagac gcttacaaag ggggaaagaa ggagattcag cccaagcttg
     6301 agaccgatag tggccatcct gaaagcgagt aatgcgccca caacctttat ggtgctgctg
     6361 acgagctgcg gatttgccgc tatccatttg ccaacactgt ccattaaagg aataaatgtt
     6421 tcacccaact ggagcaaagc cggacgcaag gattgcccga tgctgatagc agaatcatta
     6481 aagccgatct gcattctgcg ccagcgacct tcaagcgtat cattctgctt tgcagcatcc
     6541 ttatccaggg tagaaattgc agccggagca ttcatttcct gcttactgga aaggtattta
     6601 tcccagccct gtcgcattga cagtaaatgg ttgacagtct gaatatcggt aaagacctca
     6661 gccagaccaa atgactccat gagtttctgc tgaccttcct gatcgcctct tgctcctgca
     6721 gctttccatt gctgcaagaa cgctttgcct ttactgtcga taaaacggtt ggcaatcatc
     6781 agtgaagctt cgtactgcga aaaaccctga gcgacgtaat tctgcattga cccctggtaa
     6841 tccaccccgg ctttagcata tttctggatg gtatctccgc ggcccattgc tgccagccag
     6901 ttggacatat tggtgaccgc ttcctctgca gagccactac ctttaccgac ctccagactg
     6961 gcaacaatct gggtaatcgc atcttttcca taaataccac gagcagcgaa ggctttagcc
     7021 ataccgggta atgcttttgc catatccttc agctcaaatg acccaagttt ggctcctgtt
     7081 gccgcaatac caaacgcctg ttcaagttct ttcgcatcag tgattctgag tgcatcgctg
     7141 aaggcataag tcattttggc aaggtcggtc atatcggctt tggttgctgt agcggtcttt
     7201 ccaagcatct ctgcaaacgt tgctgcccgt tcgggggcca taccatcagc aactaattgt
     7261 ccgactcccc ctaacagaga ctcctgcagt tggttaacct tcagcgaggc ttgtctgata
     7321 gcctggccaa ttgcacgttc ctgttttgca tccaggtctc ctgtgacact gatatcccgc
     7381 aactgtgatt caaacgaggc atattgttta accgaggcca tgaccggtgc gcccagcgtt
     7441 ctgccaatag cataggtttc tgcaccctga ccatagagcg ccaggcggtt agccttcaac
     7501 gcatcaccgg tggctgatac tgctgacaga cggcgctgct gacgttcaat ttgctccatg
     7561 gtgcggctta cccgcagcaa ctcgctgttg agatgctgca tccgggaaga acccagttga
     7621 ccataacgtt ctgttgcccg ggttaaggca ttctggcgtt cctgcagacg gcgggaggta
     7681 tcaccaaggg aatcaagggc gcgtcgggtg ccactgacgg ctgagcggaa gctgctcccg
     7741 acaatgccgc caataatgac gccgactgaa aattcactgg ccacggtggc tatcctctga
     7801 aagcaaaaaa aacggaaggg aagtgtctga aacccatgca gaacagccgc gactggcggc
     7861 tgttaagtga tacgttgtta ctgattgtcg ccgaactcgc ttttgatttg ctcttcagcc
     7921 tgctccagcc acatctccag atcgtcagta tcgagggcat caatctcccc cggttgaaac
     7981 ctgaaccatc tcgccagcag gccctgcgcc tgcatcagtg tttttgtcgc tcttgcccag
     8041 cccagtgatt ttctgaaatc gtttctgcag ctccatatag tcggcaagat ccatgttatc
     8101 gaggtcttcc gggaggatac cggtgctacg ggcaatcagt ggttcgtccc agtctgccgg
     8161 gtctttgttg attttgcgca cctgcttcag gtcttttact gtcaggcgtt tcagttcaat
     8221 ctgttcaatt ctggtacctg cagcagtggt gaaaggataa gacagcgtaa aagtatcgga
     8281 ctgggtctgt gacatgatca tactcctttg taaattcaga gcagtatgtc tggcggtgga
     8341 cgtgacggat attaaagggg attaagaaga aggggccgga gcccctgtga tgtcagcaag
     8401 tgcgaaaacc cttgcagtta cgcaggaaag cgatgagaag cgcctttccc tcagatttgc
     8461 cggtgccgga gaaccactgg tcgggcggct tccatgcttc aatcaaatcg gccagtttgc
     8521 gggcctttga acgtgtgcag tcaatcgggt cattggtttt acgggtatta aagagggtct
     8581 ccacccccgg aatatcaagg agggtaaacc acgtaccatt tgacatgccc agtgacgcac
     8641 atcgccctcc tttgtcagtc agttcaacac tcaccgtcag cccccgatat tgattcgata
     8701 gtcagtcagt tgatcaacgc caccgacgcg gaagatgttg gccagatagt ccagttgcag
     8761 caactcttca ccatccagta cctgtctgat atacgtgcag gtgaagctac tggagaactc
     8821 ggcgttctcg tgctgtttga acgtccccag cgggttcttc ttgaacataa ttgtcaggaa
     8881 ggtgaccagc gggatttcgt cgatcagccc ctgcgagctg tagcgctgga cgctggagcg
     8941 acactgcagc gccagcgact tgtacgggtt cgcggcagac aacatcgcat cgcggtaaaa
     9001 gctgttccat ttgatttcgc cttccagttt gtcaaaacca gccgggagtt ccaccttacc
     9061 caccatcccc agtgccttgt gctcctgcat aatcatggag acatcgggga gtttaacttc
     9121 ctcagcccgt cccagcaggt tagtaccatc cagatagatg ttggcattcg tgattcggtt
     9181 tatctcaatc tttgacatca gttgccccct ttcagggtta acaggtattc cgaggtgatt
     9241 tcagtctcaa acgtcagtcg ctccagcggc ggtggtggcg tatatttgta gctcagcaac
     9301 aggtgcccgg cggccagctc cgtctccgga ttgcgggccg gatcaaacca gcaacggaag
     9361 cccagtaccg caccatcacc agtcattttg cgaccgtagg cgttgaccga ctccgtcagt
     9421 gcatcaatca gcgcctgagt aatcggcatg tcgatgtact gctggctgaa gtaacgaatg
     9481 gactcgttga tcacatcacc ggtgcggcga acgttctcaa agttacgcat atgggtgacc
     9541 gttggccatg ctgccgtccg gttaccccac agatgaaggc cgctgccgta actgctgaat
     9601 accgtggtga tcccctgttc gttaagcagg ttcacctcgc tctgcggatc gtcaatcatt
     9661 gccgacagct ggcgctccac gccggtgatc cccagaattt cctgattgga ggatgaccac
     9721 cagtaccctt tgtccaggtc gactttggca cgcaggcccg ccgcacgctg gctcagtggc
     9781 tccagacgct ccgtgttcgt caccgggtca tataccttca catgcgggta gcacaggcgg
     9841 acacggtcag agctggtatt aaagttaatg gtgccttccg ggccacgtcc cgccagagcc
     9901 tgcgcaaaag tggtaccaac cggcgcatca atataggtta ctgctcccag tttctcagcc
     9961 atggcgataa gctcaaccga gacgctgttc tgggtgcaga ataccggagc aatcaggatt
    10021 ttggcgaagt agccaaacag gttaaaactg tcgttaagca gcttcatgcc ggtacggttg
    10081 cctgcagcgt taacggtacc gatgatatca gccggggtga ctttggtcgg atcagcatag
    10141 ttatagctgg ccttcaccgt tgcatctgca gcaatgcttt tacccaggtt agtaatcacc
    10201 ccggtctgtg catcaagcga gtagtcctga ccttcaacat aaggctgacc gttgctgtcc
    10261 ggtttcagta ccagctgcgc gaccaccgga ttagccagcc gggctctgcc tgtcgccttg
    10321 tcgaacgaca cattctcact gaccacagcg attttatgca cagacggatc gagtacgtta
    10381 atgaccagaa cggtgcctgc accatggtca taaatcgcat ccagcgcctg cggaatgata
    10441 aagccggtga actggctgcc aaatgccgca gcgtctttct cagacaggca ctgtaccagc
    10501 gtattgacat cccccatcgg ggcggtacca atcaggccaa taacggcaga tttcaccgtt
    10561 ttaaccgggc gggctccgtt ttccacctca atggtttcga cgccatgcag atagttagct
    10621 gccatgggag tcctccgttt tcacttcgct gtcactgctg cttctgcgct ttggtgactg
    10681 cacagccggt gtgacggcgg gtttagtatc ttctggtacc ggcgtcagat gcttcagcgc
    10741 caccagtacc ttcacgtagt catgctcctc cggcagggaa accgtcttcc ccggccagag
    10801 caggatttcg gttccgtccg acagcgtgac gccgctggcc gggccggaat agcggtattc
    10861 tttcatcact cgctttcctc atagttcact tcggttaaca gcgggccgga cggtaaatcg
    10921 ctgtcttcga taaagacgct ttcagtcgcg aagtcgaggg cgtattgcca cagccccctg
    10981 acttcaccga taaacacctc gcgggtcagc cagatacggc ggcggcagcc gggcggggtg
    11041 tggccgccga gaatgcggcg gacagcatcc aggacattaa tcgccccttt tttaccgttg
    11101 agctggcgga agaccaccgt gacgcagagc tggatagtct gagactggat caccgcaccg
    11161 gtatcatccg gcctgtcaaa gcgcgaaccg gcatagctca gcagcaacgc gccaaccgga
    11221 tggttcaggc gatattcagc cggtttctcc gggaagtact ccacctgcag ttgcggcagc
    11281 ttctcgcgta accgggccag taccgcatca aggacgggca gaacgttcat cagtatttct
    11341 ccagtaaacc gtcacgaccg ccgaaagtgg ccgggcggct gcgtacacga aactcgccag
    11401 gctcaggcac atctttctga gtggacggca gccccagcgt gagcctgtta tcacgtaact
    11461 ccctgagttg ccgcagcgct tctttgtggt catccttcac cgtatccggg aggtcacctt
    11521 ccgggcggcg ggcgtagagc cggtaacgga ccagcgtgat ggcaatgtcc cgcagaacag
    11581 tcggtatctc tgccagtggc aggatatagc gtccgcgcag atgggcatca atcagctcgt
    11641 cggcatagcg gatacagctg tccaccacac gggtattcac tgttgcaggc gagtcgaagt
    11701 ccatctcttc actggtgagc tcgatcagcg ttcgttccgg cacctgcgca agcaaatcct
    11761 ccagggtgca gtacatgtca caccccgcgc aggatacgaa tgacgtcgcc ttcacccccg
    11821 gcttcatcaa gtgcaatacc acaggattta ccgtcgccgg actgcggcac ggctctggcc
    11881 tgagcatctg actgaacagc cacaccacgg ctgacagcgg ccccggcctc gacagcaata
    11941 atgcccagaa cgctcaccgg cgtgctgtcg ccggtaacag catccacttc ggcaaccccg
    12001 agcgctgcgg caccggcttt acagggggta ttatctgccc cgacaaaacg ctgctgtgcc
    12061 agtgcggccc ctgccgttac ggttgtgatc agaatgacct gctgagtggt tcccataacg
    12121 cctccttatt tactgatacc ggtaatgaga tacccggcat cgccaccaac cacggcgact
    12181 ttgtagatat cggtataacg gcagtacttc accttgccgc cggctccgtc gtacttgtcg
    12241 gcaacaggca tccccttacg gcgcagggtg tagccgaagg acggctcgtt ctcgtccgcg
    12301 ctgtccgccc ccggctgcgg cttgccgacg taatgcagca tcagattgtc tccccagata
    12361 tccgtcggca cgctgtcctt atccattgcc gctttcatgg acggcaggga gacaggagca
    12421 ccgatgacga tctcttcgat ctgaaagagg tcctgcagga tctccgtggt gatgcgcttg
    12481 cgttcgttgg ctccgatggc tgcctgaatt gccgggtgga acttcagcag cgccatcacg
    12541 ccggccccca tggtcatcag gttaggacgc agccccgtgg ccgtacggac cgcttccata
    12601 ccggcttcaa ttaccccgat ggggtccccc ttaccaccgg cccagcggtc gccggctgtc
    12661 agttttttaa cgtgcccggt acggtagacc ttttcatcct gagccagacg ggcggcgata
    12721 agttcacggc gcagattcac gccattcgtg gcgcgacgga tggccttgct ctcctcgtta
    12781 aacatggact ccgcctgttc gcgatagtcc actggcgcag ccagatcgtg ctcacccagc
    12841 accagatcaa gcgtgccggt tttctcacgg accagaacat tgctgtccgc cccgacggca
    12901 cgctcggtgt catattccac aaaggcggtt ttcccgaagg tcggcacacg cacgccttcc
    12961 ttgtccgtca gcacgacggg gaaaatacgt tcgccaatga atgcggcatt tttatagcct
    13021 cgggcgatac tggtcagtac cggatcaacg acacgtttac cttttaagta atcagacatg
    13081 ctctctcctt aaattacagg cagcgtgcga cagcagcctc atagctgatg ccttcttttt
    13141 tggacagggc cactgctttc tgatgcaggg ccagacgctc aggatcggct tccgcaaact
    13201 ccgccacatc caccttcacc gcgtcgccga cacgatcctt tgtggcctgt tcggcgaagt
    13261 tcatcaccgg ctccccgtcg gagagcaatg aacggaaggc ggtggccagc ggtgtgcggc
    13321 tttccccctc agcaaactcc accggcttgt cgccaccggc gacggcatcc agcagggcaa
    13381 ccaccacgga ggaggcgcgg ggagccagac gcccctctgc gaccagtttt tctgcaaagg
    13441 ccacattgtc cttatgcagt tgctcctgtc tgacctgtgc atcacgcgca tcgcgatcag
    13501 cagcctgctg cttcaggcgg cggttctcct cctgaagggc ttcaatctct tcttttgtca
    13561 tcgatgattc ctcgttactt gcggaagacg gccccgggcc tgtctcactg aattgtgcac
    13621 ctgctgcatc ctgcgacagt gtgtcgcggt acgcctcttc gcgcagactg ttgagctgcc
    13681 attccggcag gactttttct gcctcgtcca gactgaagcg ggcgatcaga aaatcgcgca
    13741 gctttcccca cagggaggca ttcgtgatgg cctgccagtc ggcgaactcc accacacctt
    13801 cttcctgctc actgaaggac acctgtttca gccctttgac ggaaggtggc tgtgccccga
    13861 gaaagcccac atggcgaagg tagagcacgc cgggcttcgg attggacggt gaatccggga
    13921 ggtagaaaga ggcggacact tttttgaatc gtccgtcggt gaccatctca gcaaactgcg
    13981 ggtccagctg ggcaggctct gccatcagat cgacgccgct gagcgacagg gctttcaccc
    14041 agccccacgc cgggtcttcc gttctgggat gaccaatcac gagtggtgct tcatggacgg
    14101 acgggtcata ggctttcacg caggcggcaa gatcgtctgg cgtgaacggc agttttttgc
    14161 cgtgcatatc ggtatgagta ccggctttaa aaatgtgaat ggctgacatt ttgctgtccc
    14221 gcgttatgtt gtcggagaca gtttgtgaga aatgcaggcc cggcgatttt aatctgcttt
    14281 agaaaacatc aggggagaag gacagggaaa gcaatgcggt gaaccggagg cggttataaa
    14341 acagaggctg taaagccttt ataaaggtaa tacagcccct cattcgctgg caatgataaa
    14401 tcacccacct gaagagagaa aactcagcga cgggccgctg attcaagatg gcggacaatg
    14461 gtatcgagga tggggattac cacttcaggc tgtagttctc catcccccgt caccggcagg
    14521 aacgggcggg ccggaagttc aacagactca ttacgccccg ttttaccccc gaactggtga
    14581 atggcaccgt aaacaacgtt ggtccccaca acagcctgcc ggtcgtcatg gtcggttgat
    14641 actgacccca tcagacgccc ggtatcctgc agtgtctgcc cgtcacgttc ttccgctgcc
    14701 agcgagggca tccaccccgg acgcccctca tcaagaaagt taaactgtgt ttccgccagc
    14761 agggttccgg cgattttgcg catcgcgggc tccatgtctg tggcagccag atccagcgca
    14821 cggaggctcc ggcgcaggga tttatcgtta atggtgatac tgaccaggtt atcggaagcc
    14881 attgttatcc tctcagttcc tgttgtgcca gtggctgaag cgtaccctga tagcgggcca
    14941 ggtcgggacg gtatgctgcc cccggtgcat aagaccagcc gacgtcggtg gtcaccttcg
    15001 tggtgccggt attaaaggtg gccacgttcc gcatttcgcc ggttttctct gagaccagtt
    15061 tcagttcctg gcccatggca gagccggagc tgataacctt caggccacgg gcacgtacat
    15121 ccgtcgcact cagggcaatc acactacagc ggcagcgcca gccgttcggc gggtaaaatg
    15181 cctgccagaa cgggtcatcc cagcgcagca ccagaccatg cagcgccaga tggctcctgc
    15241 gggtatggct gtcgttgatg ccggtataca tccagtacgg cctgtcgtcg acgttttcca
    15301 tctgttccgc ccaacgaccg gcgctgtaga gtacggacat attggtgcga aagatggtat
    15361 cgagccgcca cggactgccc tgctgaatgg tgaccggctt acccgttacc gggtcagtcg
    15421 tgtcacgtgg tccccaccat cccttacgct tcagcaccgg ctccagctcc tgccggaacc
    15481 agcgatcggt ttttccttca tcgacagcct gctgcagtgc cccgcgaata tcttccagga
    15541 tatccaggcg ggtcacttta gcaacggtaa aggcgcgggc atgggcctcc tgccacattt
    15601 cttcccagtc ccaggtaatc tgataccctt tggacttcag gtaactgact gcccgcttcg
    15661 ggggaagcgt catgcagtac gccagttcag ccgttgtcac gctcatgcag gcgtccccag
    15721 atatttgcca caaagagaat gcgggccagc cgttcctgca gatcgtccgt gttcatctga
    15781 gggtagagct ccgccagttc gcccagcagc tcagtcgggt taaccccgtt ttcgacccgc
    15841 ttaaacagag gtgccaggac gggttccagc gtgccattta acacacctcc gttcatcaga
    15901 atgtccagcg cgtcgtcaag ctgctgctga gcctgaatat cggcatcaat cgcctcggca
    15961 aatgacagcg gcagcatgtt attctggcgt tccgacggtg gtgtctcgtc aatatcgccg
    16021 tcctgcagct ggtactcacg cttaaagtat tgcggggtca gacgcagacc cgcccgggtg
    16081 agtttttcgt cgcgggtggc gcgggtgtca tcaatggtct cctgttccca catggcccag
    16141 accggacacg gcacatcgcc gaagttcagg gtgaccaccg ttctgataac ctgattcact
    16201 gctgcctgaa tgatgtccgc atccgcatcg cggatatcag ccgttacctc cagcccggcc
    16261 tgtgctgagg ccttgttact gttcgcttcc gtggtctgat tctgaccaag taatgcaatg
    16321 gagatctcac tgcgtgacag tgtgatcagc tcgcggaata cctcgctgct gtccgcctta
    16381 ccatccgcgg ctttgagttc gatgctgctg tcatcgggga tggcggccac cgcgtcctcc
    16441 accatctgct ccatggagtc cagcagtttt tcaatctctg catcatttgc acccctcggg
    16501 tgcttaccga tcacccacgg ggagccaaac ttttcggcaa agcggagcca gaatttcatc
    16561 ccgcctttct tgaaggcgac cggccagaag cacatggaca ggtccgggaa accgtaagga
    16621 ttgtcatacg aggcatcctg tgccggcacc acgaattttg acggtgacag cagctcaccc
    16681 tccacacccg catcacgcgc ccggaagcgc aggcagttgt ccgtatcaaa ctgaaaccac
    16741 tcaggcggtt tgccgacaat atccgtcact gcccacgccc tgaccgaacg gccccacatg
    16801 atttcacagg gctgataccc gtagagcacg gcatcactca tctcaccgat gatgcgggac
    16861 agatccagat cgtcgagcat gtcgcggatg aaacggaaga cccgggcaga agcgtgaccg
    16921 cgctccagtc cacgctccag tgatttgagc gctgctttac gtctgcggat acagccccca
    16981 accagcgggt cggtgcgcag ttcgcggtag atacggatat cccgtccctg agccttgaga
    17041 atgggatcag gattgggcag atacatgccc agtccgtaaa agtcgatcgc gcggctgcgg
    17101 gaggcaatct gcgcggtcag tgatttctga ggctcagaaa aagcaacaaa ttcatcgggt
    17161 gaaacccaga tacccctcgc catcagaatc cctccagcat acgggccgcc tgacgacgac
    17221 agcgtgagct tgccttcacc ggccctttgt taatttcacg gctggcgaaa tacgccagcg
    17281 ccagtgcgat ggctgaatcc ccgtggcgtt taccaccgtc agcctttgct tttgagcgtt
    17341 gctccggcac gcgggggaca ccgttcacca cctgaacggc ccgcaggtca tccagtgtgt
    17401 cttcatcctt tggtaagtcc accaggttac cgtcttccag tgcagctttg accggaggca
    17461 tatgctcccg gtaccagcct tcagttggca tcacctgctg aacccggctg gagccgtagc
    17521 gctgcatggc gtattcagcc agataggcac cattaccacg ggcatcaaac gctgcaccca
    17581 gcagaccggg caggccatcc atcagatacc aggtgatttg ctcctgctgt ctgaacggca
    17641 cgttacgcag ctccagtacg aatggcacgc gtcgtaccag gttcttctcc tgcagcaggg
    17701 gatagtccac cgacaaatca ccgctacggc caaagtcgcg ccccaggaaa gagcgggcat
    17761 cagcggggag tgcctccagc aagggtttca gatgctcatc aagccagtcc tgtgtctcgt
    17821 ggaagcgaac ctcatcagac agcagttcat aaccttcctg acaggtcaga cgcaataccg
    17881 gcgtatcagc ggacatgcgg gactctatca gggcacggga cagccaggcg ccgccaccgt
    17941 tggccggaat acagtcaagc tcttcggatg cgccggcagc gtagaatttg tacaccgacg
    18001 ccatccaggc ctgctcggat gcctctgacc attccttccc ggtgcgcaga caaacgcgcc
    18061 ggaacagccc ctcagatacg gcttcccgga aagtgatgcg atgtacgctg cctccctgac
    18121 gtccggcacg gatatccccg ataagcgtat tgaacggatt gtcgtcaccg tcatgggtgg
    18181 agataacgcg tacctttccc ccccagataa gcatcgccag cgccgctttc agcagttcgt
    18241 ccagttgctc atggaacgcc gcttcgtcga taacaataat accctgacgg ccacgcaggt
    18301 tagacgggcg gctggagagc gcaacaatac gaaagccgga gtcaggaaat ttgatggtgt
    18361 aagtcttgat gtgtttgtcg tcgtcgtcct cttcccagaa tccttcttca atttcactgg
    18421 ccgcatagtt gaatgcccgt gcccacattg cacacgcctg aatgtattcg acggtcatgt
    18481 cctggttata agcgatgtaa tacacattca tcccgcctgc tggcgcagaa gaggcggcgg
    18541 tcagtacgtt atcggatgcc tcagcccatg taataccggt acgacggctc ttttctatca
    18601 ccttaagcgg agaggtgtct gccacccagc gctgctggta aggcaacaga acgggagggg
    18661 catccagcgc cgaggtatca ggcaaaacgg gagcaaggtt attcctcccg tccatgggac
    18721 tcatcccttc ggggccgccg ccagcggcgt ttaaaatcac tccggatgat tttgtcatgt
    18781 ggcaatcccc agaatctcgc gacgaagcgc ctgtactgcg tcgcttgaca gtcccccctt
    18841 acgggcaatt ttctcggcgt tgctggctgc ctgctgcgct ctggcccgta cttcagactg
    18901 gaactttttg aggttgacgg acgcgcggga cagcgtagcc acattcttcg ccaccttcga
    18961 cagcagggcc acgcgttctt taggatcgac ttcgccttct tccgcctcct gcaactggac
    19021 aatactctcg aacagctcgg tctgaataag ggctatcaca gcctccgaac gcgcatcctg
    19081 atcgtctgct gcgccttcgg tcagcatgcg ggccgcttct gttgccgcac ggatagcacc
    19141 atagcggcgc tcaatcttct gtccatagcg atggatagcg gatttgctga taacgtaccc
    19201 ccgctcacgc agcagggact ccagctcgtt atacccgctg aagccggatt cagtcagcgc
    19261 ccgttcaagc cagcggcgca cgtcttccgg cagcttttct attgtgctgc gtctggccat
    19321 tattcactcc agtacttttc cgggcgggca atacccggac cacattccac ggtgtattcc
    19381 accaggtcta cgccgaggcg ggtcaggtca gcaaaccagt cgccagaagg ttttttctcc
    19441 agatcaacca ttttacggtc agccagataa tccagttcgc ggcgcagttc cagcggtgtg
    19501 gtgtccgggt agatggcacg ggacacatcc agcagcagcg tctcgctggc ggtgtaaggg
    19561 cgggtcttgt tcagggcaac cagcagactc cagcgcaggg attcgcggcg tacccgggta
    19621 atatcgacca ttattgacct ccggtattgc ggtactgctg taccacttcc agtttgttat
    19681 aaagcgcgtc cagtttggcc tcaatgactg tctggccacg gatataatcc tctcgacgga
    19741 cataattcag cggtaaatcc gctttaaatc gcataaattc tttttccagc tcgccccagt
    19801 tggaggcgga ttgttgcagg gcctgttcaa gggaggcgaa tcgtgccgcc tggcgttctt
    19861 ctgttttact gaacaaccat ttggcgagcc ctcccacaaa ccccatgaag gtgagcagaa
    19921 aactcactac cgtccagaat tcaacctgca gtgtcatttc tgtaatcctt cccgttcatc
    19981 cagtaacgcg tttatctggt tccgccagcg acgacattgt cctgcgttgt cgatgatgtt
    20041 ggcgagaacg tcacgctggg agacacccga atcgcgtaac cgggtgtcag tggtttcagg
    20101 ttgcccggtc gctgtgccag agcgggtgcc agcggcggca actgagtctg aatgaccggt
    20161 gtcgacggat gcattgtcat atccgagtgc ggcgttgtac tggcgcacga aaccgcgagt
    20221 aaacacgcac tcaatgggat ggctcttacc tttttcatca atccagcgct gtgtgacatc
    20281 gttaatttgc ccctgtagtt gtttattccg gctctccagt tgagcaatct gctcaagata
    20341 accggcttca gcccgctgcc cggcggccac ctgctcctga taccgtctgg cccaggcccg
    20401 cagcgcagca ttctcaagcg ttgcctgctc cgttttgtac gcgtcaaatg ctgactgcaa
    20461 ctgactgagc gcggtatcac cgtcacgctt tgcagagtca tgaccacttc tgtatcccat
    20521 ggcatacagg ccgaccagaa aggcattgat aagaatggcc agcagaatgc cgcgccacgg
    20581 cagcttttta accagatgcc acacaactgc agcctcccca tgtgagatat cgcggtgcca
    20641 gttcgcgcag gatgcgctgc ggataatggc ggttctcccg ccagctggcc gcattgcgtc
    20701 cggcattcac cgtggcgaca tgtccgaacc agcgggtgct gtccagacct ttctgtgatg
    20761 caagccgcct gtcccgttgt acccagccca gaccaccgtt atagcccgac aatgtcatgg
    20821 ccatacgctc gcagtcgttg gcggcgctga cgcgctgcca cagccagcgg tcatagctga
    20881 ccagcgcccg gatagcccat gcaggattaa acggctcacg attgctcagc atcggtatca
    20941 actggcttat ccagtcggca gtggcaggca tgaactgcgc cagtccctga gcgccagccg
    21001 gcgagaccac atcaggtcgc cagccgcttt cctgatgcag ttgcgcggcg aaatcggcca
    21061 ccggcgcaga cagtccccat tcaagccggg cattacggat cacatcatcg cgatactgca
    21121 gcgcagcctg cggaggctgc gctgcgcggg cctgactgaa gaagccgcca caccagagca
    21181 gccagacaat caccaggttg ccagcaagct gccaccagaa gctgtattta tcgttacgtg
    21241 gttctccgtg tctgatggcg gttacgccca gaccaaaggc gaacagaata atgagggtga
    21301 tttgaggcca gttcatggtc acagtcctgt tgccacagcc agacagaccg ctgcaacaat
    21361 cagtgcacgg cggattaacg cagcagaaaa tacaaggtga aggccggtct gcacagggaa
    21421 acgcccttca gccatcagtc tgtcgtcatg tttcaggtac tgaccgggac gggctttggg
    21481 gaagagcgaa cggtcaagcc agtaacccag cactgctgcc agcgtgatga gtgccagctt
    21541 gtagatcaca acaggcaact gctgtggcga gaccagagcg atgatgccca gcaacagcac
    21601 tgaggtcagc agccagccgc tgaggcgagg ttttttaaca gggggaatga attttttcag
    21661 gtttttcatg tgtgtctcct cgtttggtgg agacagcatc acaaatgtgg cgggatacgg
    21721 attttaaaca gcgttaatag tgaagatgta aacgtgcact gcatgatggc tttgaaagaa
    21781 cgaccagccc ggtacccgaa caccgggctg gccatcgccc cacaggaatg cgctgtgagc
    21841 cgacacgaaa cccctcttgg aattccatac gacgatacag agctgtcagc atctcaaatg
    21901 aaatcgccac gattaaacct cagtcatcca catttcccta aattcttcag gtacattacg
    21961 tagggtgata atatttgttt ccggatcata atcaatatag ccttcagttt tcccttcccg
    22021 gtcaaactta agttcccaat atttagactt gcctttaaaa gataccagag cccgaatgac
    22081 tcgaccatca ggaacgaagc catccgataa ctccaactct tcagcagcaa gtttaccaga
    22141 taactcctcg ggagcctggg gccaaatggc attaacaagg gtttcaagac taagtggttc
    22201 accagcctta cttagtgcat gtaagtgttc aaacgcactc ttaagaaatg catctttttc
    22261 agcgccgtca agtcctttct ctgccgcaaa tgcttttaaa acgtcacgta acttttcaga
    22321 ctctcgtttg gcgattaaga catcattaca gcctaggaac tgtgtgcgtc ctgcatattt
    22381 tgcacaaata tcgtttataa ggcgctgaga ggcttcagta actagacctt cttcaggact
    22441 caatctctca gaagcgtctc catttgaaag tgagttgggg ctggcatacc ggacatctgt
    22501 gagaatgatg caagcatcga caaaatactt atccccggcg ctgaaaccaa atgtgccaac
    22561 gttggcacat ttgggaaaag ccaaactttt cgaattaatg acagaagacg acgaagagct
    22621 tgccgaactg gccgacggcg gcacagttgc cggcctgacg cttgacgacg ttgatcgcat
    22681 gtcagtacgc gaacttcgcc aggccctgcg cgaagcgcgc gaaaccaacg cagcacaaca
    22741 gcgcgtactc gccgataaaa atgaaaaaat tgattctctc tctaccagac tggaaaagaa
    22801 atcccgtatt cagccgcctg agcctgatga ggaggttaag aagctgcggg cggaagtgac
    22861 agcattagcg gttgaggcgg aatctgctat cgccgttcga ctgtccagcg cttttgagac
    22921 actgtgcgca tattgagctg aaaacatgat tgataccccc agagacttca tggcaggcct
    22981 ggtctgtcaa ctggaaagca cagcgcgtag cctgcgctcc acatttgacc tgccggacga
    23041 gccaacaggc aatgcagcgc cttcatggct gactgagccg acgccacaga ttaacgggct
    23101 ggaggcataa ccaatgaatg ctgccctgac tgaacgactg gtttatgtcg cccgcgcggc
    23161 acgtgacgcg gggcatggta aacgcggtgc aatatacgac gctgcctgtg ctgaacttgg
    23221 catgtcccgc gccactctgc tgcgcaggct gaaggaggtc tctgtgactg ataaacgcaa
    23281 aaaacgcgcc gatgccgggc gcagcgccct gacccgcgac gaagccgcgc tgatatctgc
    23341 cacactgcgt gaggccaccc gcaagaacgg taagcgtctc tattccatcg cggatgcagt
    23401 ggaaaccctg cgggctaacg gctttatctc cgcaggcaga acagatgaaa ccaccggtga
    23461 gtttttcccg ttgtccgaag atgccatcag ccgtgccctg cgtaactatg gcctgcaccc
    23521 ggaacaactg gatgcccctg caccatatac tgaagtggcc agtctgcatc ccaatcatgt
    23581 ctggcagatt gatgcctcgc tctgcacgct ttactacctg agcaatggac ataaagggct
    23641 gcaggtgatg gacagcgcga agttctacaa gaacaagccc gctaaccttg cccgtatcgc
    23701 cagtgaccgc gtgtggagtt acgagattac cgaccatgcc agcggctgga tttacgttga
    23761 gtatgtgacg ggggcggaat ccggtgagaa cctgtgttct gtgcttatca acgccatgca
    23821 ggagcgtggc ggcgcagacg tgttgcacgg tgtgccgaaa atactctatc tcgaccccgg
    23881 ctcggcaaac accgcgggta tgacgaaaaa catgtgtcgc tcactgggca ttgacctgat
    23941 agcgcacaag ccgcataacg cccgcgccac cggacaggtg gaaaaggcgc gtgacattat
    24001 cgaacgcaag ctggagccgg gtctgaagtt ccggccggtt cacagtctgg aagaactcaa
    24061 cgcgctggcc gcgaaatggc gcagccactt taacgccacg gctgttcaca gccgccacgg
    24121 taaaacccgc acggatatct ggctgaagat tactgctgag cagctgaaaa aagcgccttc
    24181 cgttgaggta tgtcgtgaac tggctgtggc ggcaccagaa ctccgcaaag tcacgccaaa
    24241 acttcgtgtc tcgttccggg gcactgaatt tgacgtatca acggtaccgg gcgtactggt
    24301 cggtgaaaaa ctgatgatta cccgtaaccc gtggcgcagc gatgtggcac aggtggttct
    24361 gaccggtgag gacggccacg agacgttctt cctggtcgaa gaggtcagaa agaacgagtt
    24421 tggctttgct gaaggcgcgg cggtatttgg cgaaagttac aaagccctgc cggaaacccc
    24481 ggcgcagatg gcggcaaaag aaaccgaagc gctggtcacc ggtacagaca acgccgcaga
    24541 tgcagctgcc gcacgcaagg cgaaggcgct gccgttcggc gggcggcttg acccgtataa
    24601 acatattgat gacgccacac ttccggcctg tataccgaag cgaggtcagg cctctgacgt
    24661 acgcggaccg cgcactgaac agcgtcccat gactcatgtg gaggccgcga aagccctgcg
    24721 cgggaagttc agcgccaacg gccttacctg gacgccggaa cattaccgcc agttaacggc
    24781 acagtatccg gacggcgtac cggaagccgc actggatgaa gtcatggcta cgctgaccac
    24841 gccggcccgc agcagcgtta tcagcattgt taacggcaac tgaggaggga aacatgctgg
    24901 tactgaagca gcaactgaaa gaggcccgta ttccacaggc ggtggtggcg agagctgtcg
    24961 atgtttctga ggccacgctg gcccagattg tgaatcataa cgcgtggccc cgcaccagcc
    25021 ccggagaagt gcgccggcgt cttgcgtcct ggctggaaag tcaggggatt gatacagcga
    25081 agagttttga tgctgtacag ggcgcggcca cgccccgtac agcgggtacc acagataaaa
    25141 cgagcctcag tgaggaagag aatatgttac tcaaaaaaca ggtgttattt ccagcaacca
    25201 aaaaagcgtt tggtcttttc cgtgacccgt tcgccgacga agccatgcag ggttctgatg
    25261 atgtgttcac cacaccagac attcgctacg tgcgtgaggc gttgtaccag acagcccgtc
    25321 atggtgggtt tatggccgtc atcggtgagt ccggtgcggg taaatccacg ctgcgccgtg
    25381 acctgactga acgtatcaac cgcgagaatg cgccagtgat tgttatcgag ccatacatca
    25441 tcgctatgga agacaacgat gtgaaaggga aaactctgaa ggcagcagcg attgccgaag
    25501 ccattatcag taccatcgca ccactggaaa gcatcagacg cagtcaggac gcccgctttc
    25561 gccagttgca tcgcgtcctg aaagacagca accaggcggg gttcagccac gttctggtga
    25621 ttgaggaggc tcacagtttg cccattccga cactgaaaca cctcaaacgc ttttttgagc
    25681 tggagtccgg tttcaaaaag ctgctgtcca tcgtgctgat tggccagccg gaactggcga
    25741 caaaactctc tgaacgcaac atggaagtcc gcgaagtcgt tcagcgctgt gaggtggtcg
    25801 aacttctgcc tctggacaat caccttgaag aatttctgac gttcaaactg caacgggccg
    25861 gtaaacaact gacggacatt atggacgcca gcgcagtgga tgccatacgt acccgcctga
    25921 gcaatccggg aagtcatcgt aaaaatatgg tcagcctgct gtatccgctg gccgtcagta
    25981 acctggtaat agccgccatg aatctggccg ctgaaatcgg ggttccacag gtcaacgctg
    26041 acgttgtcaa aggggtttaa taatgaaatc caccacaggt atcaaccagc aaatcagtaa
    26101 agtgcagtca gccattatgg cgcttaaggc gacgaacacg gatgtacaaa gcatcaccat
    26161 caggggtaac aaacctgtca tccgcgtttc caggagtgcg cattgcatgc gcatgcttga
    26221 gcagggaaag gcctgttatc tgtataccgg acatgaccac aggggatatt tccgtcaggg
    26281 cgttttcgaa ctgcacggct gtcgcgtcgt gtggccggaa tctttgtggt aatcagcaca
    26341 actggagaaa tcataaaaaa tggcaaaaag tacaaaaggt gcaaaacgta tcaaggccgc
    26401 agcagcactc tgggtgccgg ggacacgtga agaggtcatt gagggcatca gactgctcgg
    26461 tgacgcacac cgtgaactgg tcagggctga aacagaaatg aatgacgcca ttggcgatat
    26521 caccgcacgt tatgccccgc tcaccgagag cctgaaaaaa cgcatggccg aactgcagtc
    26581 cggtattcag acatggtgtg aggcacaccg tgatgaactg accggcaacg ggaaggtgaa
    26641 gtttgctaac ctcaccaccg gcgaggtgca gtggcgaaac cgcccgccgt cagtcagcat
    26701 tcgcggagcg gataatgtta ttgaactact gagacgtctg gggcttgagc gctttattcg
    26761 tgtaaaagag gaaataaata aagacgctat cctgaatgaa aaagaggccg tgaaaaatat
    26821 tcccggtatt tccattaaaa gcgacattga ggatttttca ataattcctt ttgagcagga
    26881 tgtgcagtaa acacaccacg ttaattattt aataaaaaca ttttcttttt tattccggcg
    26941 tcagcgccgt gggcttctgc acgctggaaa cagaggagaa ttaaattatg atatttaaat
    27001 gtattcagtg cgagagggat ataacagccc tgcgttttca cagcgccatc gccgtgatgt
    27061 ccggtaaata ccacatccct gcggtacgcg tcaccctggt ctgcccgtac tgcagccagc
    27121 atttttcggc agacgtgcct gtcatggaat tctcccgccc tgacagggag gacgcgcaat
    27181 gattacccca caggaagcac gccagcgtac ccgcgccctt gttgaacact atgtcaacga
    27241 gtgtgaatgc cgcgacctca ccgatgtgaa gcacgtcctg acggcgctaa tcagcatggc
    27301 cacgcaggcc attgtggcga ccaacggaaa ggcggctgca ctgcaggtac tggtgaacac
    27361 actcacccac acggcagaga acgaggtgcc gtaccggatg gaaaccactg cagaaggcgg
    27421 cctgcacatc accgtcagcc ggaagcactg agggcgcggc atgacacgga acaccgaact
    27481 cacccgcacc gccctctacc gtctggccct gcagcgtttc gggccggacg cacaggccct
    27541 gaaactgaca gaagaggccg ctgaactggc ggccagtgcc gcccgcaacc tgaacggaca
    27601 gggcagcgaa agtgacctcg cggcagagct ggcagacgtg gaaatcatga cagagcagct
    27661 gcgccttcag ggaatggacc ggctgattga cttccacaaa cagaaaaaac tggaacgcct
    27721 tgccgcacgg ctgggcgtca catacaccgg agaaatcata tgaaccgcac cgaacagacg
    27781 ccacaactga cgccggaaga tgctgcacag cgtattcggg tactggaaga cgaaaacgaa
    27841 tacctgcgca agagatttga agaggtggac ctgtacttcg ggcgcaatct ggtcgtcatg
    27901 aaagctgcag tgattgagtg gcgggccacc ggtgatgcca ggaacggcat ggcgtggatt
    27961 tacaacaccc tgtgtgggcc gggcgaactg ccgccgcaag aggagaaaga ggcacaggaa
    28021 tacttcaaca gggaaactga agttatcgac agaaaactgg ctgccctgta ccactggttc
    28081 aggaaatacc acaggacaca cgccgcacct gaccagacca ccacaggagg taccagtgac
    28141 tgacaccatt atggaaattg tggtatgggc tttcctgctt actggtatag ccgtgtgcat
    28201 ctgcgccgga ttcgccctgg ttgccctgct gacccacgtg gtgacgcagt ggttatggga
    28261 aaagcttaaa gcagcataca gcctgaaaga gctgtccgac gctgttcggg catgggaaca
    28321 gcaaaaaaat accggagata ctgaacaatg acagaccagg ataagcacat tgagaaactg
    28381 aaaaagttgc tggcgctggc agcatccggc aacccgcatg aggctgctct ggcactgcgc
    28441 cgcgcccgta aactgatgga tgttcacggc atcacacatt ccgacatcgc catgagtgat
    28501 attgatgaaa ccatcagtca ctactggccg acaggcagcc tccgtccgcc gcgctacatg
    28561 ctgggcctga tgaacatcat ccgcgaggca tttggtgtta actccatcat tcaccccggc
    28621 acatatccgg gtgtggggtt ctacggcaac cgggaacggg ccgcactggc cgcgtacacc
    28681 tgggaagtgc tggcccgtca gctgaaaaag gcgcgtcagc agtatatcag tgcacagaac
    28741 aaaagaataa aaaccgccac ccgcaccagc cgtggagacc agtttgctga aggctgggtg
    28801 ctggccgtta tcagtgaaat acagtccttc gccctgaccg atgacgaacg tgaactgatg
    28861 cagcagtggc tggaacataa atacccgcag acgcaaacca ccagggcgcg taaaccggga
    28921 agaagtcgca atggcgacgc ctcgcgctat gcggggtttc gagaagggca gaacgtcaga
    28981 ctgcaccgac cggtcagtgg gcgggaacag cagaaactgg aggccagatg attacgttat
    29041 caggtaacag ccggaaatta aaagcctgcc gaatatctgc cagatacctt tttgcccgcg
    29101 ccttttttaa gaacgtcagg ccggggatca caattggtgt tattgccgga cgcgaacagg
    29161 ttgaaaaata catgtcaggt gcatggtgga ataaagaccc tgtcattgct gcccgtaata
    29221 ttcatatcag ttggggggat attcagaatg acgactgaat ctgttgtatg tgccctgttc
    29281 tggtattgtt ttgtcggttg gtgtactgct gaactgcacc gccgttcagg gttttattca
    29341 cgttacagtg gtgccggtta ctggattagc tggtcggtga tgttcctgtg ctggcctgtg
    29401 gcacttcctt tatatgtcga ttatatcggt gatgcaggca gaaggagcaa caatgatgac
    29461 taaacaacgt cttatccagc tcattcatat tgcccgtaat gaactgggta tggatgaaga
    29521 cacctaccgc cagatgttac aggggctgac cggtaaagcc tcaaccaaag gaatggatac
    29581 cacacaacta aactgcgtgc tggaatccat gaaaaggaaa ggctttcgcg ttaggcctgc
    29641 aggaaaagcc agctccggtt taccgctgga taaccatccg caatccagga aaatccgtgc
    29701 gctatggctt gaaatggctg ctgccggcat tgttcgtgac cgttcagaaa atgcattagc
    29761 gcggtggatc aagcgggaaa cgggcatcag cgccctgcgc tggctcaata ctgaacaggc
    29821 aagcagtgtt attgagaaac tgaagaagtg gcagcgcaga gctgcgggag taaaacatga
    29881 gcgacctgaa tcagtttcga agtaaagggc cggaactcct ggtggaactg gcacagcata
    29941 cctctgagac cgttcgcgag attattgata ttgagcccgc aattgccgac cagattggtc
    30001 aggccgtcgc gaaccgcatg atgcaggtct ggggcgggca aaacgtttat ttcccgatgg
    30061 gcatggtatg gaaggtcagt cagcgcgacc gggaaatctt cagggagttt aacggacgta
    30121 accaccatga actggcccgc aaatttggtg tttcgcttca gtgggtctac agcgtggtta
    30181 agcgggtaag aaaagaagaa ctggatcgga tgcagggcaa gctatttgct gatgaacccg
    30241 atgtagatac ggagaaaaaa gagtaatatc tgcaatcagg ctggcgcgag ttctgttttt
    30301 gttcgggccg gtctgatttt cacatactgt aaggttattg catattcctc ctggtctctt
    30361 cccattttga cccagttctt cccataaata tctcacttat tccctgtcat ttatctcaag
    30421 tctaatcacc tgatggcgac gcgcgcctta tttatagagg tcggcgctga tggtgatgtt
    30481 attaccgcgc tcctgccact gacgcgtaat atgataatac ttagcgcctt tcttcgccgc
    30541 gcgtttggcg acctggtagg agatttctgt catattgccg tagttgccgg tgaacttaac
    30601 gctgtcgaaa ggcaccatca tcgcagccgt cgctttattc agctcctcaa cttttgtgcc
    30661 atccggaagt gtgacagtgt aacgcccgcc tttggaggat tgcgtttcga agaaacggcc
    30721 tacttcggcg ctcggcgagg ctgacgtggc gacgcctgga atttcgactt tcttcgcagc
    30781 ttcgccgccc tgagccagcg cggcacggcc agcttcagag tctgccggaa tagcgtccgg
    30841 gctctggacg atgcgttttt tcgcatcttg tttatagata aatacagtga tgcgttggtt
    30901 tccgccctga ttcgcatcta tctgacgaac aatatagaaa gcgtatgcgc ctttttgttt
    30961 cgccgctttc gtaatggcat cgttaacttc cggctggcta cggtagaagc cctgaacggt
    31021 gacggtgtca tacggttcta attgtacggc ctggtctttc ggtaattcca cgatgccatt
    31081 aatgacacga tttttgggcg cgtcggcttt cggcgcgtcg gctttataca cgtccgccac
    31141 aacacgccag ttaccactgt tgccgaactc cgaggtgtcg acaacataga aggaggctgc
    31201 gccttcttta tctgcgcggc gggacacggc ggagaccgca tcgccaatag cattaaaacg
    31261 accggtaata acgatgcggt cataaggttt tagtgcagcc gcttgctccg gcgtcagttc
    31321 tgttgctgca tggacagaaa aagcagccgc agaaagcaga gccgacgcca ggagagtgtt
    31381 cttaagcttc ataaaaataa tcctttgcct tgcgcaaacc aggtactggt attgttattg
    31441 actagaaacg tggctgatta ttgcatttaa accatatgga tgtctgcggg atttttcacg
    31501 catcgtgtca tgtatcctat ctttgatgat aacatttact gatatgtcga aaaaaacggc
    31561 gtccgggcgg ctaagctaat gaagcgcata aatttaataa gttaatttaa tgttaatttc
    31621 ttgatctcgc caggggttta atgatgtttt gctgtcaaat ttgagcgaat tatcagccct
    31681 cgcaggccat tttcaaggca ttatggctgc ttagcggctg aatcgttcat gttttgtaaa
    31741 tttgataaaa aattctgttt tttggcgcta gatcacaggc gttattttca gtaggttata
    31801 gagagtttgt aacggtttta ttctgctggg gtaacattta cctcaaacgc gggcaggcgt
    31861 acgcttctcg cgcttactga caaaccatca tcaaaaatac cgatggaagg gaacatttat
    31921 gcgaattggc ataccaaaag agcggttacc caatgaaacc cgtgtcgctg cgacgccgaa
    31981 aacggtagag cagctactga agctggggtt tagcgtcgct atcgaaagcg gggcgggtca
    32041 actggcaagt tttgacgaca aagcgtttgc gcaggctggc gcggatattg tagacggcaa
    32101 tgctatctgg caatcggaaa ttattctcaa ggttaatgcg cctgaagaag aggaaatcgc
    32161 tttactgaac cccgggacta cgctggtcag ttttatctgg cctgcgcaaa atcctgggtt
    32221 aatggagaaa cttgccgaac gtaaggttac ggtgatggcg atggactccg tgccgcgtat
    32281 ttcccgcgcg cagtcgctcg acgcgttaag ctcaatggcg aatatcgcgg gttatcgcgc
    32341 cattgtagag gccgcgcatg aatttgggcg cttctttacc gggcaaatca ctgccgccgg
    32401 gaaagtgccg ccggcgaagg tgatggtgat tggcgcgggc gttgccggtc ttgcggctat
    32461 cggcgcggca aacagcctgg gggcgattgt ccgcgcgttt gacactcgtc ctgaagtcaa
    32521 agagcaggtc cagagtatgg gggctgagtt cctcgaactg gattttaaag aggaagccgg
    32581 tagcggcgat ggttacgcca aagtgatgtc cgaggcgttt atcaaagcgg aaatggcgct
    32641 ctttgccgcc caggccaaag aagtcgatat cattgttacc accgcgttga ttccgggcaa
    32701 acctgcgccg aagctgatta cccgcgatat ggtcgattct atgaaggccg gcagcgtgat
    32761 tgtcgacctg gccgcgcaga acggcggtaa ctgcgaatat accgtcgcca atcaggttgt
    32821 gacgacggac aatggcgtaa aagtgattgg ctacaccgat ctaccggggc gtttgccgac
    32881 gcagtcatcc cagctttatg gcaccaacct ggttaacctg ctgaagctgc tgtgcaaaga
    32941 gaaagacggc aatattgacg tggattttga cgatgtcgtg atccgtggcg tgacggtgat
    33001 tcgtgacggc gacattacct ggcctgcgcc gccaatccag gtttccgcgc agccacaggc
    33061 cgcgcctaaa gcagcacctg cgccaaaaga gccggaaaag cccgcttccc cctggcggaa
    33121 gtatgcgtta atggcgctgg cgatcattct ttttggctgg ctggccgatg tcgcgccaaa
    33181 agagttcctc ggccatttta ccgtgtttgc gctcgcctgc gtggttggtt attacgtggt
    33241 gtggaacgtg tctcatgcgc ttcatacgcc attaatgtcg gtgaccaacg caatttcagg
    33301 gattattgtt gtcggggcat tattgcaaat tggtcagggc ggctgggtca gcttcctgag
    33361 ctttatcgcg gtgcttatcg ccagcattaa tattttcggt ggcttcaccg tgactcagcg
    33421 tatgctgaaa atgttccgga aaaactaagg ggtaacacat gtctggagga ttagttacag
    33481 ctgcatacat tgttgccgcg atcctgttta ttttcagtct tgccgggctt tcaaagcatg
    33541 aaacgtcccg ccaggggaat aacttcggta ttgccgggat ggcgatcgcg ctgctggcga
    33601 ccattttcgg gccggatacc ggcaacgtgg catggattct ggtcgccatg attattggcg
    33661 gcgcgattgg catccgcatg gcgaaaaaag ttgagatgac cgagatgccg gagctggtcg
    33721 cgattctgca cagtttcgtg ggcctggcgg cggtactggt tggctttaac agctatctgt
    33781 accatgacgc cagtctggca ccggtgctgg tgaatatcca tctgaccgaa gtcttcctcg
    33841 gtatctttat tggcgcagtc actttcactg gatcgatcgt agcgtttggt aaactgcgcg
    33901 gcaaaatctc ttctaagccg ttgatgttgc ctaaccgtca caaaatgaat ctggcggcgc
    33961 tggttgtttc tttcctgttg ctgctggttt ttgttcgtac cgaaagcgtg ggtctacagg
    34021 ttctggcgct actgctgatg accattatcg cgctggcgtt tggttggcat ctggtcgctt
    34081 ctatcggcgg ggcggacatg ccggtggttg tttcaatgct gaactcctat tccggttggg
    34141 ctgccgcggc ggctggcttc atgttgagca acgatttgct gattgtgacc ggcgcgctgg
    34201 tcggttcgtc aggcgcgatc ctgtcttaca ttatgtgtaa agcgatgaac cgctctttca
    34261 tcagcgttat tgctggtggg ttcggtactg acggctcctc aacgggcgac gatcaggaag
    34321 ctggcgaaca tcgcgaaatt acggcggaag agaccgctga gatgctgaaa aactcccact
    34381 ccgtcattat tacgccgggg tacgggatgg cggtagcgca ggcgcagtat ccggtggcgg
    34441 aaatcaccga aaaactgcgt gcgcgcggta tcaacgtgcg tttcggcatt catccggtgg
    34501 cgggtcgcct gccggggcat atgaacgtgc tgttggcgga ggcgaaagtg ccttatgaca
    34561 tcgtgctgga aatggacgaa atcaatgatg atttcgccga taccgatacc gtgctggtga
    34621 ttggcgcgaa cgatacggtg aacccggcgg cgcaagacga tccccgcagc ccgatcgccg
    34681 gtatgccggt tctcgaagtg tggaaagcac agaatgtcgt ggtctttaag cgttccatga
    34741 atactggtta tgctggtgtg cagaacccgc tgttctttaa agagaatacg caaatgctgt
    34801 ttggcgatgc caaagccagc gtggatgcaa ttctgaaagc gctttaatct tttaaacgtg
    34861 cggcggcctc tttggaggcc gtttttatac atttcaccct ataagctgcc tctttgttgg
    34921 ctgcgctcag aaaccccggt cacatcgtta tctatgctcc cggggatttc ttcccttgcc
    34981 gccgcgatgc atcttgaatg attttgtgta tatattgcat tttatctttt gtttaaatcg
    35041 ctaagcagaa cggcgatact ctgcccgccg gtggtctgtt cgagggcgat tttgacaatg
    35101 atggttaacg gaacggagag caacatgccc accggaccta atagccagcc ccagaaaatt
    35161 aacgacaaaa ataccactaa ggttgaaagg cctaaaccac gtcccatgat acgtggctca
    35221 aggatattgc cgaagaccag attaatcagc agatagcccg ccagcaccag cagcgcatca
    35281 taaaacccgt taaataccag cacctgaata atgggcggca gggcagcgag caccgatcca
    35341 atattaggga tatagttcag cgcgaaggcc agtagacccc agacaaaggc gaagcggaca
    35401 tccagagcgg ccagcattcc ccatgcgacc agtcccgtca cgatactgat cgctgttttt
    35461 agcaccagat aatgtgaaac gctatcaagc gcgcgttgaa ttgccgccat accttctacc
    35521 ggacggctca tcatctgctg cagtttttca ggcagttgtg gaacctccag cagcatgaat
    35581 accacggtca ataacaataa aaagatggat gacatggcat tggacagttg ggtgagcagg
    35641 ttcgttacca gagtcatggc ggcgtttgga tcgatatatt tcgccagctc atcaaccgac
    35701 acgccaatgc ctgctcgctg caaccacggt tcaatacgtt gcaacggtat caccaatgag
    35761 gagcgatact gcggtagggt acgggccagt tcatttaatg atgtccccaa ataggccagt
    35821 agcagtacca ttaacataac aataatcaca atgagcaatg atacggcgat aacgcgcgga
    35881 attcgacatc gggtcatccg ttgcacaacg ggattgagaa cgactgcaat aaataacgcc
    35941 aaaataaagg gaacaatgat atctgcggcg aagcggatac cgctcagaat aaccaccagc
    36001 attcccagca taatgacgat ttttagacca ttgagcgtga tgatcggttt tgccatatca
    36061 gtccctgttt tctatgccga cacgaataat aatgtgatgt cggtcgacct gttctggtta
    36121 aaatcaaaca cttcaggtaa agaagtgaaa atattttgag ttaattcctg gcttatgata
    36181 caaatcaggc gtgttcaact accgaggaca attatcatcc gcgatgacga gaagcaacac
    36241 tgcggataat tgtaatatta tggacaatat gttcagcgct tttttctcca cgcaaacgca
    36301 tcttcactct acctcctttt tcctgcttat cggcgagcag cactggcgta acgcacttta
    36361 gtctctcact tctgcctgag ctggcgcaat gcgctgtgct aactgatttt attttttagt
    36421 ttgctgcgtg cagcagactc gaaagagtat attctcatgc aggagaagtg tcatgtttta
    36481 ctggatttta ttagctctgg ctatcgcgac tgaaattacc ggcacgctct caatgaaatg
    36541 ggctagcgtg ggtaatggca atgcgggttt tattttaatg ctggtgatga tcacgctgtc
    36601 atatatattt ctttcttttg cggtaaaaaa gattgccctg ggtgtagcgt atgccttatg
    36661 ggaagggatc ggcattttat ttattaccat ttttagcgtg ctgctatttg atgaagcatt
    36721 atcaaccatg aagattgccg gcttgctgac gctggtcgcc ggcatcgtat tgatcaaatc
    36781 agggacgcgt aaacccggca aaccggtgaa ggaggcgact cgtgcaacaa tttgaatgga
    36841 tacacggcgc ctggcttggg ctggcaataa tgctggaaat cgcggctaac gttctgttga
    36901 aattttcgga cggctttcgc cgtaaatgct atggcatctt atcgcttgcc gctgttctgg
    36961 ccgccttcag cgcgctttcc caggcggtaa aagggataga cctgtcggtg gcgtatgcgc
    37021 tatggggcgg ttttggtatt gccgccacgc tggcggcggg ctgggtgctc ttcggccagc
    37081 gcttaaatcc caaaggctgg gttggcgtga tattgctgct cgccggaatg gtcatgataa
    37141 aatttgcctg agacgatcgc tgccggtcag gcagcgattc ccgcattaat cctgcgccag
    37201 agctttcagc ttatcgcgaa agccggtgac ggatatagcg cggttatcgg cgcgccagcg
    37261 atctttagcc gcaggggcgg agctttgtac gccaatgagc tgccatccgc tatccgtgtg
    37321 caataataac ggcgagccgc tgtcgccagg taacgtgtcg cactggtgtg agagtacggc
    37381 attctgcgcc cagccggtca cgacgcaatc ctgatgggaa tagagcgcat tcagatgatc
    37441 ttccggataa ccggactgcg tgacttttcg gtctgcggct ttcaacgccg cagtgagcgc
    37501 cgctttatcg ccggtaaata aaggcactgg cgtgataccg gaaggtgggt agcgcaatat
    37561 taccagacca aaatcccagc ttgccgcggc aggcggcaca atccagccat cgccatccgc
    37621 tttcaaacgt cggcccagcg acggttcaac gcggccttca atgccgtgga tttcatagcg
    37681 ccatactcct tttcgcgcca caaaacgcag cgcaaccgct ttgtccggtt ttcctttcgg
    37741 cggcgttagc aggcagtgac ctgctgtcag ggcgatatgc ggggagataa gcgttgccgt
    37801 acacaaatta ccgctggcgg tctctagttg cccgatggca tcccacggcg attgggtcgg
    37861 atcggcgacg ggcactcgat cgtcatggtt aaaaaaaagc gttttgacgt cgctggcatc
    37921 cgtggcgtct gtttcagccc ccccggcttt cgccataacc ggtaaaaaac acactatgcc
    37981 cagtaataca gcaatggttt tatgcatatc acactctggt gggtaattat gattattaac
    38041 aacaaaccct cagtactact atagacgtga cggtaagaaa gtgggagtaa aatcagataa
    38101 ctacactcag gaaagataga aatgcgtggc aataacggcg cataaaataa gcacgataag
    38161 aatgagctca aagcggtagc gagacacttt tttgccctcc cggaaggcgg cgctaaacca
    38221 gaacgattta gcgccgtaaa aacgggcgcg ggggcgcgcc gcagcatgtt acgacttacg
    38281 cagctggttg cgaagttgtt tttgacgtag atttggctgg ggcttttttg ccatcttttt
    38341 tctggtgctt tttagccgcc tgcgcttttt gctcaacggt ttttttatgc tgttttttgt
    38401 ggtgctgggt ggtctgggtt gttttggcag gcgctgcggt ttttgcaggc gttgcagtct
    38461 cagccgcgaa tgctgcggaa gagagaccca ttgcagcggc aacaaccaga gctaatactt
    38521 ttttcatttt gataccctcg atttggtttt cattcaaccc cactgcgggg ccggtgaaat
    38581 gactatatcg ctgttatcaa aaggcttccg tgagtgattg gtttcggcat gtaacgctat
    38641 gtacaatccc ccggtaacgc gatgtaagcc cccaccataa taggtagctt tacgttaccg
    38701 gccgttattt ttggtcgcag agtcggtaat atccgccctc cagaataaca ggcacaccgt
    38761 atatgaatcc gataatctgg gtggtattta cgcttctggc gctggatgca atcagagaag
    38821 tcatgggcgt atcaagcctg gcaggtctgt ggtgaacagt gagtcgtggc gtgaaaccag
    38881 cccggcgata gcgcacgttg ctatcgcc
//
LOCUS       DAJVKX010000033        38120 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000033 DAJVKX010000000
VERSION     DAJVKX010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 38120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38120
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.033"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..781
                     /locus_tag="OPY25_001676"
                     /pseudo
     CDS             1..781
                     /locus_tag="OPY25_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311470.2"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(828..2162)
                     /gene="srmB"
                     /locus_tag="OPY25_001677"
     CDS             complement(828..2162)
                     /gene="srmB"
                     /locus_tag="OPY25_001677"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HCS0927311.1"
                     /translation="MTVTTFSELELDESLLDALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTMLFSATLEGDAIKDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADNFEHKVALLKHLLKQDDATRSIVFVRKRERVHELAETLRLAGINNC
                     YLEGEMAQIKRNEGIKRLTDGRVNVLVATDVAARGIDIPDVSHVINFDMPRSGDTYLH
                     RIGRTGRAGRKGTAISLVEAHDHLLLLKIGRYIEEPLKARVIDELRPTTRAPSEKLTG
                     KPSKKVLAKRAEKKKEKEKEKPRVKKRYRDTKNIGKRRKPSGTKMQEQSSEE"
     gene            2292..3029
                     /gene="trmN"
                     /locus_tag="OPY25_001678"
     CDS             2292..3029
                     /gene="trmN"
                     /locus_tag="OPY25_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HCS0927312.1"
                     /translation="MSQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAD
                     VKRILDIGTGSGLLALMLAQRTDDSVPVDAVELDAGAAMQAQENVAHSPWPHRITVHT
                     DDIQRWAPRQTVRFDLIISNPPYYEPGVECSTPQREQARYTATLDHQTLLAIAADCIT
                     EDGFFCVVLPEQIGNAFTQQALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGSDQNYSESYTALTQAFYLFM"
     gene            complement(3014..4636)
                     /gene="nadB"
                     /locus_tag="OPY25_001679"
     CDS             complement(3014..4636)
                     /gene="nadB"
                     /locus_tag="OPY25_001679"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HCS0927313.1"
                     /translation="MMTTPELSCDVLIIGSGAAGLSLALRLAEKHKVIVLSKGPVSEG
                     STFYAQGGIAAVFDETDSIASHVEDTLIAGAGICDRHAVEFVASNARTCVQWLIDQGV
                     LFDTHVQPNGKESYHLTREGGHSHRRILHAADATGKEVETTLVSRAQNHPNIQVLERS
                     NAVDLIISDKIGLPGPRRVVGAWIWNRNKEWVETCHAKSVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGSR
                     FMPDVDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPDDFVRQHFPMIYAKLLD
                     LGMDLTKEPIPIVPAAHYTCGGVVVDDYGRTDVDGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAMDIDRRMPSVHSVDVLPAWDESRVENADERVVIQHNWHELRLLMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYANFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPQQLAESGPSILSPLTPHINR"
     gene            4900..5064
                     /gene="rseD"
                     /locus_tag="OPY25_001680"
     CDS             4900..5064
                     /gene="rseD"
                     /locus_tag="OPY25_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HCS0927314.1"
                     /translation="MEDKTCLQHDKQKQMRNGTLRNIDTLTCCLLIVRLMEWRFESAW
                     KFGLGRHYLG"
     gene            5061..5636
                     /gene="rpoE"
                     /locus_tag="OPY25_001681"
     CDS             5061..5636
                     /gene="rpoE"
                     /locus_tag="OPY25_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HCS0927315.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQESFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            5668..6318
                     /gene="rseA"
                     /locus_tag="OPY25_001682"
     CDS             5668..6318
                     /gene="rseA"
                     /locus_tag="OPY25_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HCS0927316.1"
                     /translation="MQKEKLSALMDGETLDSELLKALTHDSEMQKTWESYHLIRDSMR
                     GDTPDVLHFDISARVMAAIENEPVRQVTPLIPEAQPAPQQWQKMPFWKKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLRVPSEAAPVG
                     SQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            6318..7274
                     /gene="rseB"
                     /locus_tag="OPY25_001683"
     CDS             6318..7274
                     /gene="rseB"
                     /locus_tag="OPY25_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HCS0927317.1"
                     /translation="MKQLWFAMSLVAASLFFSVNASADPASGALLQQMNIASQSLNYE
                     LSFVSITKQGVESLRYRHARLDSRPLAQLLQLDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLAPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DMDTKLPMRVDLLDRDGETLEQFRVIAFTVSQDIGSTMQALAKANLPPLLSVPGGEKT
                     KFNWNPSWVPQGFSEVSSSRRPLPTMDNLPIESRLYSDGLFSFSVNVNRATQNSSDQM
                     LRTGRRTVYSSVRDNAEITIVGELPPQTAKRIADSIKFRAVQ"
     gene            7271..7750
                     /gene="rseC"
                     /locus_tag="OPY25_001684"
     CDS             7271..7750
                     /gene="rseC"
                     /locus_tag="OPY25_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HCS0927318.1"
                     /translation="MIKEWATVISWQNGQAVVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPSAEPLAPGQKVELGIAEKSLLGSALLVYMSPLAGLFLCAALFQMLFGS
                     DLAALSGAVLGGVGGFLVARGYSRKLAERDAWQPVILNVALPPDLVRVETTSIETRQ"
     gene            8009..9808
                     /gene="lepA"
                     /locus_tag="OPY25_001685"
     CDS             8009..9808
                     /gene="lepA"
                     /locus_tag="OPY25_001685"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCS0927319.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDFKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVTDVLERLVRDIPPPQGDPDGPLQALIIDSWFDNYLGVVSLVRIKNGTMR
                     KGDKIKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDILGAPVGDTLTS
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYESFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTAKETIYVDSPSKLPP
                     LNNIYELREPIAECHMLLPQAYLGNVITLCIEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINNERVDALALITHRDNSQSRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            9825..10799
                     /gene="lepB"
                     /locus_tag="OPY25_001686"
     CDS             9825..10799
                     /gene="lepB"
                     /locus_tag="OPY25_001686"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCS0927320.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFVFAPKRRARQAAAQTASGD
                     ALDNATLNKVAPKPGWLETGASVFPVLAIVLIVRSFLYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKITYDP
                     VAKEVTIQPGCSSGQACENALPVTYSNVEPSDFVQTFARRNGGEATSGFFEVPLNETK
                     ENGIRLTERKETLGDVTHRILMVPIAQDQLGMYYQQPGQPLATWVVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGKAVAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            11073..11753
                     /gene="rnc"
                     /locus_tag="OPY25_001687"
     CDS             11073..11753
                     /gene="rnc"
                     /locus_tag="OPY25_001687"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCS0927321.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFDLGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSNIQTVEQLILNWYKTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            11750..12655
                     /gene="era"
                     /locus_tag="OPY25_001688"
     CDS             11750..12655
                     /gene="era"
                     /locus_tag="OPY25_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCS0927322.1"
                     /translation="MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGM
                     NVDTIASIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            12667..13395
                     /gene="recO"
                     /locus_tag="OPY25_001689"
     CDS             12667..13395
                     /gene="recO"
                     /locus_tag="OPY25_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCS0927323.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     NLKGALQPFTPLLLRYSGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLNCIQALAGTTGSPEPALRRFELALLGHLGYGVNFTHCAGSGERVDD
                     TMTYRYREEKGFFASVVIDNNTFTGRHLKALEAREFPDVDTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTKKD"
     gene            13407..14138
                     /gene="pdxJ"
                     /locus_tag="OPY25_001690"
     CDS             13407..14138
                     /gene="pdxJ"
                     /locus_tag="OPY25_001690"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HCS0927324.1"
                     /translation="MAELLLGVNIDHIATLRNARGTDYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLHTRMNLEMAVTEEMLAIAVETRPHFCCLVPEKRQEVT
                     TEGGLDVAGQRDKMRDACARLAAAGIQVSLFIDADERQINAAAEVGAPFIEIHTGCYA
                     NAETDAEQAKELARIASAATLAARLGLKVNAGHGLTYHNVKAIAALPEMHELNIGHAI
                     IGRAVMTGLKEAVAEMKRLMLEARG"
     gene            14138..14518
                     /locus_tag="OPY25_001691"
     CDS             14138..14518
                     /locus_tag="OPY25_001691"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCS0927325.1"
                     /translation="MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQ
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKL
                     GVAHMHVTLADERHYACATVILES"
     gene            complement(14630..14890)
                     /locus_tag="OPY25_001692"
     CDS             complement(14630..14890)
                     /locus_tag="OPY25_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhL family 4Fe-4S dicluster ferredoxin"
                     /protein_id="HCS0927326.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGDSIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTILQDPAHVETEEQLWDKFVLMHHADKL"
     gene            complement(14943..15854)
                     /locus_tag="OPY25_001693"
     CDS             complement(14943..15854)
                     /locus_tag="OPY25_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0927327.1"
                     /translation="MNIKQLHSFLILCDELHYGRAASRLFITQPSLSQQIKQLESSLK
                     TILFKRKGRGIKLTKAGIILQRHANKIMLDLKNAENELLPYQDQQRDTISIGVSGSYL
                     VLPAFRNFMAHHPEISLNVKEFSTEQTIKKLTDSAVDIGIVYRTALPAQLSSTMLFED
                     EIIAAIPLSHPLATRERLHLKDLNDQPIIVLNDSLLLRGIITTEFNNRKVVPNVICEL
                     DNHYSCLEYAEAQIGIAFITRSLTHLSTPKNVRLVSLGIPAFFIPVMLVHSNDLSLDN
                     ATICLLKQIKNFYTVDNKSAPEKSWPE"
     gene            15970..17166
                     /locus_tag="OPY25_001694"
     CDS             15970..17166
                     /locus_tag="OPY25_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HCS0927328.1"
                     /translation="MSASINRWGMLAAHVCINFVLGGVYAFSYFKTPLMAQYHWDPAT
                     PALAFSINMGIIPLPMIWGGRMIDNGKGKQAIVIGGILFSLGFILSGFVDNLPMLFLT
                     YGVIAGLGSGLAFTGNLNNILKFFPDRRGLASGIVLAGVGVGTLLCTRLAEYFMAQTH
                     DVSRALLYLGIVYLVVIFIVQFFIRSAPAKDSGGIKASPLDKDYRHMLKDLRFWLLFM
                     ILALGVFSGMVISSSSAQIGMTQYGLLSGALVVSLVSIFNSIGRLFWGGLTDKLGGYN
                     TLVIVYLFTCVCMLLLLFFNGNTSVFYFSALGVGFAYAGILVIFLGLTSQNFGMRNQG
                     LNYGFMYFGFAVGAVIAPYVTSAIAKYTGSYNTVFILTTVLLLIGVVLTLITKKYVAT
                     VLAKIH"
     gene            17188..18105
                     /locus_tag="OPY25_001695"
     CDS             17188..18105
                     /locus_tag="OPY25_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCS0927329.1"
                     /translation="MKIAIAGAGAMGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGL
                     FVETETTQKYYPIPAMLADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILS
                     NGLGNIETLEKYVDRQKIYAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAK
                     VIATLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQA
                     VVDEFVLVAASQNIPLTEQMVMNTVKKVFDPRESGHHYPSMHQDLHKGRLTEIDYLNG
                     AIARIGAQNNIAVPVNTLLTQLIHAKEAQ"
     gene            complement(18144..18992)
                     /locus_tag="OPY25_001696"
     CDS             complement(18144..18992)
                     /locus_tag="OPY25_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCS0927330.1"
                     /translation="MNCLIRIRQRYPDLAQSDRKLADYLLAQPDTARHLSSQQLAAEA
                     GVSQSSVVKFAQKLGFKGFPALKLAISEALASNPNPHSVPVHNQIRGDDPMRLVGEKL
                     IKENVAAMHATLDVNSEEKLLESVTMLRHARRIVITGIGASGLVAQNFAWKLLKIGIN
                     AVVERDMHALLATVQALAPEDLLLAISYSGERRELNLAADETLRAGAKILAITGFSPN
                     ALQQRATRCLYTIAEEQATRSAAISSTHAQMMLTDLLFMALVQQDLERAPERIRHSEA
                     LVKKLV"
     gene            19108..20001
                     /gene="murQ"
                     /locus_tag="OPY25_001697"
     CDS             19108..20001
                     /gene="murQ"
                     /locus_tag="OPY25_001697"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCS0927331.1"
                     /translation="MNLGTLVSETRNPQTMDLDALSTPELVKRFNEQDTLVAEAVKAT
                     LPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGG
                     PGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCT
                     TVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGK
                     VYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAETLLKQTDFEVKPAILMALTGLD
                     AAAAREKLAAHQGFLRAALEH"
     gene            20012..21373
                     /locus_tag="OPY25_001698"
     CDS             20012..21373
                     /locus_tag="OPY25_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCS0927332.1"
                     /translation="MDKTAALASDILRGIGGEQNILRLENCMTRVRVEVQDDSQLDIP
                     RLKALPGVSGYVKQGEQHQLIVGPGKAAQVVDAMRVQIAAGGVKPDDAMARTKSEAKA
                     KYKAPMSDALRKLANVFIPLIPAFIASGLITGIINILKRPDIVGDVAVHYPNLLGLMG
                     IFGSAVFAIMNILVGVNTAKVFGGSQALGGVMAGILSSPQLAQITLFGEALQPGRGGV
                     IAVLLVVALMCWIERQFRKLLPGSLELILNPLLTTVITGAVAIVALQPLGGWISDAIA
                     HGASWAIDRGGFLVGAVLAGTFLPLVLIGLHQGLVPIHVELVQAHGYNALFPILAMAG
                     VGQIGAAIAVLMKTRNARLKKVIKGALPVGLLGIGEPLIFGVTLPLGKPFIGACLGGA
                     VGGALISYWKVATVITFGISGLPLALTIVAGKVLFYLLGYLIAVIAGFIFTWLLGFND
                     PEE"
     gene            21377..22012
                     /gene="yfhb"
                     /locus_tag="OPY25_001699"
     CDS             21377..22012
                     /gene="yfhb"
                     /locus_tag="OPY25_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HCS0927333.1"
                     /translation="MVSHERRVVFFDLDGTLYQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIGIGLLVKGRAARWPMSLLLWGCTFGHSETRLQAHQADFVRWFRANVTAFPVVQE
                     RLTTYLLSSDADIWLITGSPQSLVEQVYFDTPWLPRVNLIASQMARRYGGWVLTVRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSKQDNPLLYFCQHRWRVTPHGELQQLE"
     gene            22037..22588
                     /gene="tadA"
                     /locus_tag="OPY25_001700"
     CDS             22037..22588
                     /gene="tadA"
                     /locus_tag="OPY25_001700"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCS0927334.1"
                     /translation="MPPAFITGVTSLSDVELDHEYWMRHALTLAKRAWDEREVPVGAV
                     LVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVLQNYRLLDTTLYVTLEPCVMCA
                     GAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVEIIEGVLRDECATLLSDFF
                     RMRRQEIKALKKADRAEGAGPAV"
     gene            complement(22756..24183)
                     /gene="mltF"
                     /locus_tag="OPY25_001701"
     CDS             complement(22756..24183)
                     /gene="mltF"
                     /locus_tag="OPY25_001701"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HCS0927335.1"
                     /translation="MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGV
                     LRVSTIDSPLTYSVINGKKYGLDYELAQQFANYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYDSARVKNYQPGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVV
                     VNDLQRLKETKFPDLSWKVDDKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELA
                     VALDVTDEQPVTWFSRLDDDNTLSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVD
                     TRSFLRAVDNVLPELEPLFKKYAKEIDWRLLAAISYQESHWDPLATSPTGVRGLMMLT
                     KNTAQSLGLTDRTDAEQSISGGARYLEDMMAKVPETVPEDERIWFALAAYNMGYAHML
                     DARSLTVKTKGNPDSWTDVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQEAEAMKLAQDYPAV"
     gene            complement(24184..24414)
                     /locus_tag="OPY25_001702"
     CDS             complement(24184..24414)
                     /locus_tag="OPY25_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927336.1"
                     /translation="MCARGETAAIIKNLTRRRNRLRRNKITAFSCHTVRLSLRISCQL
                     AHCYAKCRSLVTYLLQQNIFFSPRQRTIQRIN"
     gene            24439..28326
                     /gene="purL"
                     /locus_tag="OPY25_001703"
                     /gene_synonym="purI"
     CDS             24439..28326
                     /gene="purL"
                     /locus_tag="OPY25_001703"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HCS0927337.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLN
                     APLNDSEQAQLTRLLQYGPALSSHTLAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     IDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSS
                     VDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHN
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALNRADITIADAVNRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAV
                     TTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPL
                     SLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAMQVLVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGD
                     DHLAALFNEELGGVIQVRAEDRDAVETLLAQYGLADCVHYLGQALAGDRFVITANDRT
                     VFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPGLNVKLSFDINEDIA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPE
                     RVFRTVANSWHPENWGEDSPWMRIFRNARKQLG"
     gene            28977..30407
                     /gene="qseE"
                     /locus_tag="OPY25_001704"
     CDS             28977..30407
                     /gene="qseE"
                     /locus_tag="OPY25_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001676035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HCS0927338.1"
                     /translation="MKRWSVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     AVTNRSTLIDARRSEAMTNVALEMERSYRQYCVLDDPTLAKVYQSQRKRYSDMLDAHA
                     GVLPDDKLYQALRQDLNALAQLQCKDSGPEAAAAARLEAFANANTEMVQATRTVVYSR
                     GQQLQQEIAERGQFFGWQALVLFLVSLAMVLLFTRMIIGPVKGIERMINRLGEGRSLG
                     NTVTFTGPRELRSVGQRIIWLSERLAWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVDILDDSSRNLQKLIEQLLDYNRKLVDSATELEAVDIAPLVDMV
                     VSAHSLPARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRS
                     QGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     EIQLVDDKAQEVCFRISLPLPASDKH"
     gene            30409..31173
                     /gene="qseG"
                     /locus_tag="OPY25_001705"
     CDS             30409..31173
                     /gene="qseG"
                     /locus_tag="OPY25_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HCS0927339.1"
                     /translation="MNLSLVRMSHVFVQTIKRCLLRWGIPVGISCLALTACVPHASQQ
                     LPGSAAQDTLPHYQLADYLPTACADIWSLRGQAVETNPLYWLRTIDCADRLMPVQSRA
                     EARALTDDNWQNAFRRGILLADAKITPPERRAIVTRLEALSAQIPAQVRPVYQIWHDG
                     QALQLALSAERQRYSKLQQTSDSELDALRQQQQALQTQLDLTTRKLESLTDIERQLST
                     RKPAGNYNADTPHTNDKPATSEDGAAPSPSQDEVTP"
     gene            31170..32507
                     /gene="glrR"
                     /locus_tag="OPY25_001706"
     CDS             31170..32507
                     /gene="glrR"
                     /locus_tag="OPY25_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HCS0927340.1"
                     /translation="MISRKPAHLLLVDDDPGLLKLLGMRLTSEGYSVVTAESGQEGLR
                     VLHREKVDLVISDLRMDEMDGMQLFTEIQKVQPGMPVIILTAHGSIPDAVAATQKGVF
                     SFLTKPIDRDALYKAIDEALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMVAQSDVS
                     VLINGQSGTGKEIFAQAIHNASPRNNKPFVAINCGALPEQLLESELFGHARGAFTGAV
                     SNREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISA
                     THRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQSAQRHKPFV
                     RAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTF
                     AEARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            32584..32922
                     /gene="glnB"
                     /locus_tag="OPY25_001707"
     CDS             32584..32922
                     /gene="glnB"
                     /locus_tag="OPY25_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HCS0927341.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(32971..34431)
                     /gene="dtpD"
                     /locus_tag="OPY25_001708"
     CDS             complement(32971..34431)
                     /gene="dtpD"
                     /locus_tag="OPY25_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HCS0927342.1"
                     /translation="MKTPSQPRAIFYIVAIQIWEYFSFYGMRALLILYLTHQLGFNDS
                     HAINLFSAYASLVYVTPILGGWLADRLLGNRVAVITGALLMTLGHVVLGLESDSTLSL
                     YAALAIIICGYGLFKSNISCLLGELYAPDDNRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGVGMFIGLLIFLSGHRHFQQTRGVNRPALRAVKFALPTWGWLVLM
                     LCIAPVFFTLLLENNWSGYVLAIVCVFAAQLIARIMVKFPEHRRALWQIVLLMITGTL
                     FWVLAQQGGSSISLFIDRFVNRHWLNMTVPTALFQSVNAIAVMAAGVVLAWLSSPKES
                     ARSVLRVWLKFAVGLILMGGGFMLLALNAHQARLDGQASMGMMIAGLALMGFAELFID
                     PVAMAQITRLNLPGVTGVLTGIYMLATGAIANWLAGVVAQQTTESQISDTAVAAYGHF
                     FSQMSEWTLSCVALIVAIVGLRWICTRTTSALPQGD"
     gene            complement(34487..36631)
                     /gene="cadA"
                     /locus_tag="OPY25_001709"
     CDS             complement(34487..36631)
                     /gene="cadA"
                     /locus_tag="OPY25_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HCS0927343.1"
                     /translation="MNVIAIMNHMGVYFKEEPIRELHRALEGLNFRIVYPNDREDLLK
                     LIENNSRLCGVIFDWDKYNLELCEEISKLNEYMPLYAFANSYSTLDVSLNDLRMQVRF
                     FEYALGAAADIAAKIRQNTDEYIDNILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSIFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNAERSYMVTN
                     GTSTANKIVGMYSAPAGSTVLIDRNCHKSLTHLMMMSDITPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDYIKKTLDVKSIHFDSAWV
                     PYTNFSPIYQGKCGMSGDRVEGKIIYETQSTHKLLAAFSQASMIHVKGDINEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLKSESDGWF
                     FDVWQPEHIDGAECWPLRSDSAWHGFKNIDNEHMYLDPIKVTILTPGMKKDGTMDEFG
                     IPASLVAKYLDERGIIVEKTGPYNLLFLFSIGIDKTKALSLLRALTEFKRAFDLNLRV
                     KNILPALYREAPEFYENMRIQELAQNIHKLVEHHNLPDLMYRAFEVLPKMVMTPYTAF
                     QKELHGETEEVYLEEMVGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKENTK"
     gene            complement(36714..38045)
                     /gene="cadB"
                     /locus_tag="OPY25_001710"
     CDS             complement(36714..38045)
                     /gene="cadB"
                     /locus_tag="OPY25_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HCS0927344.1"
                     /translation="MSSVKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWV
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPALNNPIPAGIACIAIVWLFTFINMLGGAWVSRLTTIGLFLVLIPVVL
                     TAVAGWHWFAIATYHANWNTSTTTDSHAIVKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTALAGIIYIAATQVIAGMFPASVMASSGAPFAISTSTILGGWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKIYGEMDKNGIPKKGLLLAAVKMTALM
                     ILITIMNSSGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGFNIRNSVSLICSVL
                     GCAFCFIALMGASSFELSGTFIVSLIILMFYGRKMHQRQNNDSDNNTAEAL"
BASE COUNT         8752 a         9602 c        10725 g         9041 t
ORIGIN      
        1 cgacggtaac ttttcatatt caacagcttg aacgtgagtt ttccctgcaa ctgttcgaga
       61 aaatagggcg ccgaatgtgc ctgaccaatg aggggaaaaa gctgataccg catatccatg
      121 aactgacgcg tgtgatggag tcgattcgtg aagccgcaag acaggatgcg gaacccggcg
      181 gagagctgcg cgtggcgaca ggtgaaacct tactggcata caaaatgccg caggttttac
      241 aacgttttaa gctgcgagcg ccgaatgtca gattgtcgct acagtcgctg aattgctatg
      301 tgatacgtga tgcgttgctg aatgacgagg tcgatctggg cgttttttat cgcgtaggta
      361 atgatgacgc gctcacgatg cagcaactgg gggagcagcc gctggcgctg gtggcctctc
      421 cactgctaca ggatgctgat tttacgcagc cagatcagca tatccctgca gcttcatcat
      481 caatgaaccg caatgtgtct tccgccagct atttgaaagt acgctacggc agaggcggat
      541 tacgctggaa aacaccattg aactgtggag tattgaaagc attaaacagt gtgtggctgc
      601 taacctgggc atcagctttt taccgcgatt tgccgttgaa cgagaactta gcaccggtca
      661 gttgaaagag ctgccgtttg gcgcgccgtc gctatcgatc atggcgctgt gcgcccatca
      721 tgccgggaaa gcggtcagcc cggcaatgca gatatttatg cagtgtatgg aggcgtgttt
      781 taccgtggaa gataaaaaat gccgggttaa cgaacccggc attatcatca ctcttcgctg
      841 gattgctcct gcattttcgt accgcttggc ttgcggcgct taccgatatt ttttgtatcg
      901 cggtaacgtt tcttcacgcg cggcttctct ttttctttct cttttttctt ctcggcgcgt
      961 ttcgccagca cttttttcga cggtttgccg gtcagctttt cgctgggcgc acgcgtggtc
     1021 gggcgaagct catcaatgac gcgcgctttt agcggctctt cgatgtagcg accgattttc
     1081 agcagcaaca gatggtcgtg ggcttcaacc agcgagattg cagtgccttt gcgacccgca
     1141 cggcctgtac gaccaatgcg atgcagatag gtatcgccac tgcgcggcat gtcgaagtta
     1201 atgacgtggc tgacgtcagg aatatcaatc ccgcgtgccg cgacgtcggt cgcgaccagc
     1261 acgttaacgc gaccgtcggt gagacgctta ataccctcgt tacgtttgat ctgcgccatc
     1321 tcgccttcaa gatagcaatt gttgatccct gccagacgca gcgtttcagc cagttcatgg
     1381 acgcgttcac gtttacgtac aaacacgata gaacgggttg catcgtcttg ttttagcagg
     1441 tgcttcaaca gcgcaacttt atgttcgaaa ttgtcggcac ggtagtacca ctggtgaatt
     1501 ttcttgcgct cgcgggttga cggattggcg gaaacctcaa ccgggtcttc cagcaggcgc
     1561 tcggcaaaat ctttaatcgc atcgccttcc agcgtggcgg agaacagcat cgtctgttta
     1621 cgccagcggg tctcaccagc gatatgttca atgtcctgag cgaagcccat gtcgagcatc
     1681 cggtcagctt cgtcaaggat cagtgtttca accgcccggc agtcaaaatt ctcttctttt
     1741 atatattgca gcagacggcc cgtcgtggcg accacgatat cctggttttc gctaaacact
     1801 tcagcatggt tcatataggc cacgccgccg gtaatcgtgg cgatatccag atgagtatgc
     1861 ttagccagtt cacgagcgtg atcggcaacc tgcattgcca gttcgcgggt tggcgtcagg
     1921 atcagaatgc gcggcggccc cgatttttta cgcggaaagt cgagcaggtg ctgcaacgcc
     1981 ggcagcagat atgccgccgt ttttccggtg cctgtcggcg cagaaccgag tacatcacgg
     2041 ccatcgagcg caggcggaat ggcggcagcc tgaatggcgg tcgggcgagt gaaaccttta
     2101 tcctggaggg catccagcag gctttcgtcg agttcaagtt cggaaaaagt cgttacagtc
     2161 atgttctacc tctgtgtggg gcgctgatta tagacgttac ggccgcaatc ttcatctgtt
     2221 tgtatggata tcccttctca ggtattgttt tcactcggcg ctgtcgccgt tttttgcaag
     2281 gttgttttta catgtctcag tctggctccg ttcttcgtcg taacggattt acgtttaaac
     2341 agttttttgt cgcacacgat cggtgtgcga tgaaagtggg aactgacggt attttactcg
     2401 gggcgtgggc gccggtcgcg gatgtaaagc gaattctgga tatcggtact ggaagcggtc
     2461 tgctggcgtt aatgctggcg cagcggacgg atgacagtgt gcctgttgac gccgtggaac
     2521 tggatgccgg ggctgccatg caagcgcagg aaaacgtggc tcactctcca tggccgcatc
     2581 gaataacggt gcatactgac gatattcagc gttgggcgcc tcgccagacg gtacgctttg
     2641 atcttattat cagcaacccg ccttattacg aacccggtgt ggaatgctcc acgccgcagc
     2701 gggagcaggc gcgttacacc gctacgctgg atcaccagac gttattggct attgcggcgg
     2761 attgtattac cgaagatggc tttttttgcg tagtcttgcc ggaacaaata ggtaacgctt
     2821 ttacgcagca agcgctcaac atgggatggc atttgcggtt acgtactgac gttgcggaaa
     2881 acgaagcgcg cttgccgcac cgggttttgc tcgcattctc cccgcaagcc ggggagtgct
     2941 ttagcgacag attagtaatt cgcgggtcag accagaatta ttctgaaagt tatacggcgc
     3001 tgacccaggc attttatctg tttatgtgag gcgttaacgg cgaaaggatc gatgggcctg
     3061 attcagccag ttgttgcgga taatccagcg taaagtgcag cccccggctc tctttacgca
     3121 tcatcgcgca acgcacaatc agttcggcca cttgcaccag attgcgcagc tccagtaaat
     3181 tattcgagac gcgaaagttg gcgtaatatt cgtcaatctc ttgttgcaac atagtaatac
     3241 gccgtagggc gcgctccagc cgtttcgtcg tgcgcacaat ccccacatag tcccacatca
     3301 gcagacgcag ttcgtgccag ttatgctgaa tcaccacccg ctcatcggcg ttctccacgc
     3361 ggctttcatc ccaggcggga aggacgtcaa cgctgtggac agaaggcatt cgcctgtcga
     3421 tatccattgc cgcggaccag ccgtacacta agcattccag taacgagttg gacgccatac
     3481 ggttagcgcc gtgcagaccg gtgtaactga cttcgccaat ggcatataag ccgtctacat
     3541 cggtacgacc ataatcatcg acgaccacgc cgccgcaggt atagtgcgcg gcaggaacaa
     3601 tgggaatcgg ttctttggtt aaatccatcc ccaaatcgag cagtttcgca tagatcatcg
     3661 ggaagtgctg gcggacaaaa tcgtcaggct tgtggctgat atcgagaaac atacagtctg
     3721 cgccgagtcg tttcatctca tgatcaatag cgcgggcgac aatatcgcgc ggcgccagtt
     3781 cgccgcgttc gtcaacgtcc ggcataaacc gtgaaccgtc cggacgttta aggtatgcgc
     3841 cttcgccgcg cagcgcttcg gtaaggagaa aattacgcgc ctgcgggtga taaagggcag
     3901 tgggatgaaa ctggttaaat tccagattag cgacccgaca gcccgcgcgc caggccatcg
     3961 cgataccgtc accggaggaa atatccgggt tagtggtata ttgatacacc tttgaggcgc
     4021 cgccggtcgc cagcaccacc gacttcgcat gacaggtttc aacccactct ttattgcgat
     4081 tccagatcca ggcgccgacg acccggcgag gccccggcag acctatttta tcggagataa
     4141 ttaaatcaac ggcgttgctg cgttccagca cctgaatatt aggatgattt tgtgcccgac
     4201 tgaccaacgt ggtttcgact tcctttccgg tagcgtcggc ggcatgaagg atacggcgat
     4261 ggctatggcc gccttcacgc gtgagatgat agctctcctt gccgtttggc tggacatgcg
     4321 tatcaaacag gacgccctga tcgataagcc actgcacgca ggtacgagcg ttgctggcga
     4381 caaactccac cgcgtggcga tcgcaaattc cggcgccggc aatcagcgta tcttcgacat
     4441 gcgatgcaat gctgtcggtt tcatcaaaca cggcggcaat accgccctgt gcataaaacg
     4501 tggagccctc gctcaccggc cctttactca ggacgataac cttatgcttt tcagccagac
     4561 gcagcgccag cgagagtccg gccgcgccgc tgccgataat taacacatca caggacagtt
     4621 caggagttgt catcatggtt cttgtttaat ttactaaaca tggttgcggc agattagcac
     4681 tatatggcgc taaaaagcac gttatgattt caaaagtgtt gtgcttatta aacataaaat
     4741 aaaaatacgg cgagagataa acggcaaaaa atattttata gggcagggtg ttagcgtcgg
     4801 attttgtagt gaaataaaga tgctgttagg ttactctgca aacgacgaaa tgggcatttc
     4861 tgtacagata gtgcgttgtt cagcatctgt agacttataa tggaagataa gacctgtcta
     4921 caacatgaca aacaaaaaca aatgcgtaac ggaactttac gaaacataga cactctaacc
     4981 tgttgcttgc tcatagtgcg gcttatggag tggcgtttcg aaagcgcgtg gaaatttggt
     5041 ttggggagac attacctcgg atgagcgagc agttaacgga ccaggtcctg gttgaacggg
     5101 tccagaaggg agatcagaaa gcctttaact tactggtagt gcgctaccag cataaagtgg
     5161 cgagtctggt ttcccgctat gtgccatcgg gcgacgttcc cgatgtcgta caggaatcat
     5221 ttattaaggc ctatcgcgcg ctggattctt tccgggggga tagcgctttt tatacctggt
     5281 tgtatcgtat tgcggtcaat accgcgaaga actacctggt tgcgcagggg cgtcgtccgc
     5341 cttccagtga tgtagacgcg attgaagcag aaaactttga aagcggcggc gcgctgaaag
     5401 aaatttcgaa ccctgagaac ttaatgttgt cagaagaact gagacagata gttttccgaa
     5461 ctattgagtc cctcccggaa gatttacgta tggcaatcac cttacgggag ctggatggcc
     5521 tgagctatga agagatagcg gctatcatgg attgcccggt ggggacggtg cgttcacgta
     5581 tcttccgggc gcgggaagct attgataata aagttcaacc gcttatcagg cgttgacgat
     5641 agcgggatac tggaaaaggt attaggcatg cagaaagaaa aactttccgc tttgatggat
     5701 ggcgaaacgt tggatagtga gctgctcaaa gcgcttacgc acgactcgga aatgcagaaa
     5761 acctgggaga gttatcacct gatccgcgat tcaatgcggg gggatacgcc tgacgttctc
     5821 catttcgata tatccgcccg cgtgatggcc gctattgaaa acgagccagt acgtcaggtg
     5881 acgccattaa tccctgaggc ccaacccgct ccgcagcaat ggcagaaaat gccgttctgg
     5941 aaaaaagtgc gtccgtgggc ggcgcagctt acccaaatgg gcgtggcggc gtgcgtttca
     6001 cttgcagtta tcgtcggtgt ccagcactat aatgggcaat ctgaaacatc ccaacaacct
     6061 gaaacgccgg ttttcaatac cctgcctatg atggggaaag ccagcccggt aagtctgaga
     6121 gtgccttctg aagcagcgcc tgtcggcagt cagcaacagc aggtacagga gcagcgtcgt
     6181 cgcattaatg ccatgttgca ggactatgaa ctgcagcgcc gactgcactc cgaacagctt
     6241 cagtttgagc aggcgcaaac ccagcaagcc gcggtacagg tgccaggaat ccaaacttta
     6301 ggaacgcaat cgcagtaatg aagcaacttt ggtttgccat gtcccttgtg gcggctagcc
     6361 tgttcttctc agtaaacgcc tcggccgacc ctgcgtccgg ggcgttattg cagcagatga
     6421 acatcgccag tcagtcactg aattacgagc tgtcattcgt cagcatcacg aaacaaggcg
     6481 ttgaatctct gcgttatcga cacgcacgcc tggatagtcg cccgcttgcg caattgctac
     6541 agttggacgg tccccgccgg gaggtcgtac agcgtggtaa tgaaatcagt tattttgaac
     6601 cgggccttga gccgttcacc ctgaacggtg attatattgt cgattctctg ccttccctga
     6661 tttacaccga tttcaagcgt ctggcgcctt actacgactt tatttccgtc ggacgcaccc
     6721 gtatcgcaga cagattatgc gaagttatcc gcgttgtggc gcgcgatggt acgcgttaca
     6781 gctatatcgt ctggatggac atggacacca aactaccgat gcgcgttgat ctgctggatc
     6841 gcgacggcga gacgctggag cagttccgcg ttattgcgtt cacggtgagt caggatatcg
     6901 gcagcaccat gcaggcgctg gcgaaggcga atctgccgcc gctgctttct gttcccggtg
     6961 gcgaaaaaac gaaatttaac tggaatccat cctgggtgcc gcaaggcttt agcgaagttt
     7021 ccagcagccg tcgtccgttg ccgacgatgg ataacctgcc tatcgaatcg cggctttatt
     7081 ctgacggtct gtttagcttt tccgtcaatg tgaaccgggc gacgcaaaac agcagcgatc
     7141 agatgctgcg caccgggcgc cgaacggttt atagcagcgt tcgcgacaac gcggaaatca
     7201 ccattgtcgg agagcttccg ccgcaaacgg cgaagcgcat tgccgacagt atcaaattca
     7261 gggcagtaca atgattaaag agtgggcaac cgttatctcc tggcagaatg gtcaggcggt
     7321 ggtgagctgc gacgttaaag cgtcatgcag cagctgcgcc tcccgtgcgg gatgcggcag
     7381 tcgcgtgctg aataaattag ggccgcaaac cacgcatacc attgttgtgc caagcgcgga
     7441 gccgctggct ccggggcaga aagtcgagtt gggcatcgcc gaaaaaagcc ttttaggttc
     7501 ggcgttgctg gtctatatgt cgcctttagc ggggctattt ctttgtgcgg cgctttttca
     7561 gatgctgttt ggatctgacc ttgccgcatt aagcggggcc gtgctgggcg gagtgggcgg
     7621 ttttctggtt gcccgcggct attcccgaaa actggcggag cgcgacgcct ggcagcccgt
     7681 gattttaaac gttgccctcc cgcctgacct tgtccgcgtc gaaactacct caatcgaaac
     7741 gcgccagtaa acgttttgcc caatggtaca tggtacacct gccgcgttgg gttgttgtcc
     7801 cgataagcat gcgcttttcc tgcgttgcgg tgttttacag gaaaaaagcg aggcgttttc
     7861 cagttcccgc tctccttaca ctatgaacat ttcctcgcct tagcgttgta gtgtagaatg
     7921 cggcgtttca gttaaaacag acgttaagct cagaacagcg acctctaaag tctggtcaac
     7981 caggcgtaag gcataataat ttatctctat gaagaacata cgtaactttt cgatcattgc
     8041 tcacattgac cacggtaaat cgacgctgtc tgaccgtatt atccaaatct gcggtggcct
     8101 gtctgaccgt gaaatggaag ctcaggtact tgattcgatg gatcttgagc gtgagcgcgg
     8161 tattactatt aaagcccaga gtgtgacgct ggattttaaa gcgtctgatg gtgaaactta
     8221 tcaactgaac tttatcgaca cgccgggaca cgttgacttt tcctatgaag tttcccgttc
     8281 gttagccgcc tgcgagggcg cgctgctggt ggtggatgcc ggccagggcg tagaagcgca
     8341 aacgttggcg aactgctaca ccgcgatgga aatggatctt gaagtggtgc cggtgcttaa
     8401 caagattgac ctgccggccg ccgatccgga gcgtgtggcg gaagaaatcg aagacattgt
     8461 cggcatcgat gcgacggacg cggtacgctg ctccgccaaa acgggtgtcg gcgtgacgga
     8521 cgttctggaa cgcctggtgc gcgatatccc gccgccgcaa ggcgatccgg acggcccgct
     8581 gcaggcgctg attattgact cctggttcga taactacctg ggcgtggtat ccctggtgcg
     8641 tattaaaaac ggcaccatgc gtaaaggcga caaaattaaa gtgatgagca ccgggcagac
     8701 ctacaacgct gaccgcctgg ggatcttcac gccgaaacag gttgatcgta ccgagctgaa
     8761 gtgcggcgaa gtaggctggc tggtctgcgc cattaaagat atcctcggcg cgccggttgg
     8821 cgatacctta acctcagcgc gtaacccagc tgaaaaagcg ttgccgggct ttaagaaggt
     8881 gaaaccgcag gtctatgcag gtctgttccc ggtcagctcc gacgattatg aaagtttccg
     8941 cgacgcgctc ggcaagctga gcctgaacga tgcctcactg ttttatgaac cggaaagctc
     9001 ctcggcgctg ggctttggtt tccgctgcgg cttcctcggc ctgttgcaca tggagatcat
     9061 tcaggagcgt ctggaacgcg aatacgatct ggatctgatc accactgcgc cgaccgtggt
     9121 ttatgaagta gaaacaacgg cgaaagagac tatctatgtt gatagcccct ccaagctgcc
     9181 gccgttgaat aacatttatg aactgcgcga gcctatcgcc gaatgtcata tgctgttacc
     9241 acaagcctat ttaggtaacg ttattacgct gtgtattgag aaacgcggcg tacaaactaa
     9301 catggtgtat cacggtaacc aggttgcgtt gacctatgaa atcccgatgg cggaagtggt
     9361 gctcgacttc tttgaccgtc tgaaatcaac gtcgcgcggc tatgcgtctc tggattataa
     9421 cttcaagcgc ttccaggctt ccgatatggt gcgtgttgat gtgttaatca acaacgagcg
     9481 tgtcgatgcg ctggcgctga tcacgcaccg tgataactcg caaagccgtg gtcgcgagct
     9541 ggtggagaaa atgaaagatt tgattccacg ccagcagttt gatatcgcga ttcaggcggc
     9601 gattggtacg catattattg cccgttcgac ggtaaaacag ttacgtaaaa acgtgctggc
     9661 gaagtgctac ggcggcgata tcagtcgtaa gaaaaaactg ctgcagaaac agaaagaagg
     9721 taagaaacgc atgaagcaga tcggtaacgt cgagctgcct caggaggcgt tcctcgccat
     9781 tctgcatgtc ggtaaagaca ataaataatc cctaaggagt tggcatggcg aacatgtttg
     9841 ccctgattct ggtgatagcc acactggtga cgggcatttt atggtgcgtt gataagtttg
     9901 ttttcgcgcc aaaacgtcgg gcgcgccagg ctgccgcgca aacggcgtcg ggagatgcgc
     9961 tggataacgc tacgctcaat aaagtggcgc ctaagccggg ctggctggag accggggcgt
    10021 cggttttccc ggttctggcg atcgttctga tcgttcgttc atttctttat gaaccctttc
    10081 agatcccgtc aggctcaatg atgccgacac tgcttatcgg cgattttatt ctggtggaaa
    10141 aatttgccta cggcattaaa gatccgatct accagaaaac cctgattgaa accggtcatc
    10201 caaagcgcgg ggatattgtg gtatttaaat atccggaaga tcctaagtta gattacatca
    10261 aacgcgccgt cggtttgccg ggcgataaaa tcacttatga tccggttgcg aaagaggtga
    10321 cgattcagcc tggctgtagc tccggtcagg cgtgcgaaaa tgcgctgccg gttacctact
    10381 ctaacgttga gccgagcgat tttgtacaga cctttgcccg ccgtaacggc ggagaagcga
    10441 ccagcggttt ctttgaggtt ccgctaaacg agacaaaaga aaacggcatt cgcctgaccg
    10501 aacgtaaaga gacgttaggc gatgtgaccc accgcatcct gatggtgccg atagcccagg
    10561 atcagttggg catgtattac caacagccag gacaaccgct ggcgacctgg gttgtaccgc
    10621 cggggcaata tttcatgatg ggcgacaacc gcgataacag cgcggatagt cgttactggg
    10681 gatttgttcc ggaagcgaat ctggtcggta aagcggtcgc tatctggatg agctttgaca
    10741 agcaggaagg ggagtggccg acaggcgtac gcctgagtcg tatcggcggt attcactaac
    10801 tgtggcgaaa tgatcgttca cgctgtcgtc tttttagcgg cagcgtgaat tatttcctgg
    10861 ataaattccc tcagactaac gacatcccct gtcgttgtgt atagaatatt cccccgaagt
    10921 tttaggttgg cgccgtttgg tcgccacggc acacgaaaca gcgttggtta tagacaacct
    10981 tctttccgct gcagcgatgc ggcaggacag atgacgtgta tcaggtctgt ttcgtgtgct
    11041 ggattgttga cgcattcatt tattggtatc gcatgaaccc catcgtaatt aatcggcttc
    11101 aacggaagct gggctacact tttaatcatc aggagctgtt gcagcaggca ttaactcacc
    11161 gcagcgccag cagtaaacat aacgaacgcc tggagttttt aggcgattca atcctgagct
    11221 tcgttatcgc taacgcgctt tatcaccgtt ttccacgggt ggatgaggga gatatgagcc
    11281 gtatgcgcgc cacgttggta cgtggtaata cgctggcgga attagcccgt gaatttgatt
    11341 taggcgagtg cctgcgttta gggccgggcg aattaaaaag cggcggattt cgtcgggagt
    11401 ccattctggc ggacaccgtg gaagcgttaa tcggcggagt atttctcgat agcaatatcc
    11461 agaccgtcga gcagttaatc cttaactggt ataaaacccg tctggatgag ataagtccgg
    11521 gcgataaaca aaaagatcct aaaacgcgct tgcaggagta tttgcagggt cgccatctgc
    11581 cgctgccatc ttacctggtt gtgcaggtac gcggcgaggc gcacgatcag gaatttacta
    11641 tccactgcca ggtcagcggc ctgagcgaac cggtggttgg cacgggttcc agccgtcgta
    11701 aggcggagca ggctgccgcc gaacaggcgc tgaaaaaact ggagttggaa tgagcaccga
    11761 caaaacttac tgcggattta ttgccatcgt cggacgtccg aacgttggca aatccacctt
    11821 gctgaacaaa ctgctcgggc agaagatttc gatcacttcc cgtaaagcgc agaccacgcg
    11881 ccaccgcatt gtcggtattc ataccgaagg cccgtatcag gcaatctatg tcgatacccc
    11941 gggactgcat atggaagaaa agcgcgccat taaccgtttg atgaataagg cggcgagcag
    12001 ttcgattggc gacgttgagc tggtgatttt cgttgtagaa ggcacccgtt ggacgccgga
    12061 cgacgaaatg gtcctgaaca aactgcgcga tggcaaagcg ccggttattc tcgccgttaa
    12121 caaggtggat aacgtgcagg aaaaagccga tttgctgccg cacctccagt tcctggcaag
    12181 ccagatgaac tttcttgata tcgtccccat ctctgctgaa acgggtatga acgtcgatac
    12241 cattgccagt atcgtgcgta aacatttacc ggaagcgatt caccacttcc cggaagatta
    12301 tatcaccgat cgctctcagc gctttatggc gtctgaaatc attcgtgaaa agctgatgcg
    12361 ttttctcggc gccgagctgc cgtattccgt taccgttgag attgaacgtt ttgttaccaa
    12421 cgaacgcggc ggctatgata tcaacgggct gatcctcgtc gagcgcgaag ggcagaagaa
    12481 gatggtgatt ggcaacaaag gcgccaaaat caaaaccatt ggtattgaag cgcgtaaaga
    12541 catgcaggag atgtttgaag cgccggtaca cctggaactg tgggtgaaag tgaaatccgg
    12601 ctgggccgat gacgaacgcg ctctgcgcag tctcggttac gtagacgatc tgtgagttaa
    12661 cacagcgtgg aagggtggca gcgcgcattt gtcctgcaca gtcgcccctg gagcgaaacc
    12721 agcctgatgc tggacgtctt cacggaagaa tcggggcgcg tgcgccttgt cgccaaaggc
    12781 gcgcgatcta aacgttccaa tctgaaaggc gcgttgcagc cttttacgcc gttattgcta
    12841 cgctacagcg gacgcggcga ggtgaaaacc ctgcgcagcg ccgaggcagt ttctctggcg
    12901 ctgccgttaa gcggtattac gctctatagc ggcctgtata tcaacgaact cctctctcgc
    12961 gtactggaat atgaaacgcg cttctccgaa ctcttttttg attatctgaa ctgtattcag
    13021 gcgctggcgg gaaccaccgg ctcgcctgaa ccggcgttgc gacgtttcga actggcgttg
    13081 ctgggacatc tggggtatgg cgtcaatttc acccactgtg caggcagcgg cgaacgggtg
    13141 gatgacacca tgacctaccg ttaccgcgaa gaaaaaggct ttttcgccag cgtcgtcatc
    13201 gataacaaca cctttaccgg acggcacctg aaagcgctgg aggcgcggga atttccggat
    13261 gtagataccc tgcgtgccgc taaacgcttt acccgtatgg cattaaagcc gtatcttggg
    13321 ggaaaaccgt taaaaagccg ggagctgttc cggcaattta tgcccaaacg cacagtaaaa
    13381 acgaagaaag attaacgagg attgtcatgg ctgaattact gttaggcgtc aatattgacc
    13441 acattgccac gttacgtaat gcgcgcggca ccgactatcc ggatccggta caggcggcgt
    13501 ttattgctga acaggcaggc gcggacggca ttaccgtaca cctgcgcgaa gatcgtcgcc
    13561 acattaccga tcgcgatgtg cgcattctgc gtcagacgct gcatacgcgt atgaatctgg
    13621 agatggcggt gaccgaagag atgctggcga tcgccgtaga aaccaggccg catttctgtt
    13681 gtctggtgcc ggaaaaacgc caggaagtca ccaccgaagg cggcctggat gtggccggac
    13741 agcgcgataa aatgcgtgat gcctgtgcgc gcctagcggc ggctggcatc caggtttcgc
    13801 tctttatcga tgccgatgaa aggcaaatca acgcggcggc ggaagtcggc gcgccgttta
    13861 tcgaaatcca taccggctgc tatgccaacg cagaaaccga tgcggaacag gcaaaagagc
    13921 tggcgcgtat tgccagcgcc gcgaccctgg cggcccgtct ggggctaaaa gtaaatgcgg
    13981 gtcatggcct gacctaccat aacgtcaaag ctattgccgc actgccggaa atgcacgagc
    14041 tcaatatcgg tcatgccatt attggtcggg cggtgatgac ggggctgaaa gaggcggtgg
    14101 ctgaaatgaa acgtttgatg ctggaagcgc gcggctaatg gcgattctcg gcctgggaac
    14161 ggatattgta gagattgccc gcattgaggc agtgatctcc cgttccggcg aacgtctggc
    14221 aaggcgtgtg ctcagtgaca acgagtgggc tatctgggag acgcatcagc agccggtgcg
    14281 ttttctcgcc aagcgttttg cggtcaaaga ggcggcagcg aaagcttttg gcaccggcat
    14341 ccgcaacggt ctggcgttta atcagttcga agtgtttaac gatgagctgg gaaaaccacg
    14401 tttgcggctg tggggcgagg cgttaacgct ggcggaaaaa ctcggtgtgg cgcacatgca
    14461 tgtcacgttg gccgatgaac gccattacgc ctgcgctacg gtcattctgg aaagttagat
    14521 ttgccggatg gcggcgtaaa cacgttatct gacctacagg ccgatatatt gccggcctga
    14581 taagcatagc gccatcaggc attgttgcgt tggaagtgcg ttaacccgct tacaatttat
    14641 ctgcgtgatg catcagaaca aacttatccc acaactgttc ttcggtttcg acatgggcgg
    14701 gatcctgcaa aatcgtattg gggatcgggc agactttctg acaggtcggc gtttcgtaat
    14761 ggcctacaca ctcggtgcat ttgtcgctgt taatctcata aatgctgtcg cccattgaaa
    14821 tcgcctcatt cgggcactcc ggctcgcaca tatcgcaatt gatacatttt ttggtgatta
    14881 acagcgccat caggaaattc tcagaaacaa cacaaatcgg gcgggcatta tacgcctatt
    14941 ttctactcgg gccagctctt ttctggcgct gatttgttat ctacagtgta aaaatttttg
    15001 atctgcttga gcaggcagat ggttgcgtta tccagtgaaa ggtcattact gtgcaccagc
    15061 atgacaggaa taaagaatgc ggggatgccc agtgaaacca ggcgaacatt tttgggtgtc
    15121 gataaatggg ttagcgagcg ggtaataaat gcgatgccaa tctgcgcttc ggcatactca
    15181 aggcatgagt agtggttatc cagttcgcag atgacgttag gaacgacttt gcggttatta
    15241 aattctgtgg tgatgatccc tcttaatagc agagagtcat taagcacgat aatgggctgg
    15301 tcgtttaaat cttttagatg cagacgttcg cgtgtcgcca gaggatgaga aagtgggatt
    15361 gcagcgataa tttcatcttc aaacagcatg gtcgagctta gctgggcagg gagcgctgtt
    15421 cgataaacaa tgccaatatc aacggcgcta tccgtcagct ttttaatggt ttgctcagtt
    15481 gagaactctt taacatttaa agatatttcc ggatggtgcg ccataaagtt gcgaaaagcg
    15541 ggcaggacca ggtagctgcc tgacaccccg attgaaatag tatcgcgctg ttgatcctga
    15601 tagggaagaa gttcattttc ggcatttttt aaatccagca ttattttgtt agcgtgtcgt
    15661 tgcaaaataa tgcctgcttt tgttaattta attcctctgc cttttcgctt aaataatatt
    15721 gttttaagtg atgactcaag ttgtttgatt tgctgactta atgatggctg agtgataaat
    15781 aggcgactgg ctgcccgacc ataatgtaat tcatcacaca atatcaggaa ggagtgtagt
    15841 tgtttgatat tcattaaaat ttaatgccaa tcgattgggt tttgttataa cgattataaa
    15901 aaataccaaa ttgtttgcct attttgcttt ttttaaactg tgatcagtgc attttaaaaa
    15961 gggaaaatta tgtcggcatc aatcaaccgc tggggaatgc ttgccgctca cgtgtgcatc
    16021 aattttgtgc tcgggggcgt ctacgcattt agctatttca aaacaccact catggcgcaa
    16081 tatcactggg atccggctac gccggcgtta gcattctcta tcaatatggg gatcattcct
    16141 ttaccgatga tttggggcgg gagaatgatc gacaatggta aaggaaagca ggcgatagtt
    16201 atcggcggta tcctgttttc tttaggtttt atcttgtccg ggtttgtgga taatttgccc
    16261 atgctgtttt taacctacgg cgtcattgcc gggttgggat cgggcctggc ttttacgggt
    16321 aatcttaata atattctgaa atttttccct gaccgtcgcg gtcttgccag cggtatcgta
    16381 ctggcgggtg ttggcgtcgg gacgctactt tgcacccgcc tggccgaata ttttatggcg
    16441 caaactcacg atgttagtcg ggcgttgtta tatctgggta ttgtttatct ggtggttatt
    16501 tttatcgtcc agttctttat tcgtagcgcg ccagcaaaag atagcggagg aattaaagcc
    16561 tcgccactgg ataaagacta tcggcacatg ctgaaagatc tgcgcttctg gctgctgttt
    16621 atgattctgg cgctgggcgt gttctctggg atggtaatta gctcaagttc tgcgcaaatt
    16681 ggtatgacgc agtacggttt actgtccggt gcattagtcg ttagcctggt ctcgatattt
    16741 aactcgatcg gtcgcctgtt ctggggaggg ttaaccgata aattaggcgg ctataatacg
    16801 ctggttattg tttatctttt tacctgcgtc tgtatgctgc tgctgttgtt cttcaacggt
    16861 aatacttcgg tattctattt cagcgctctg ggcgtgggct ttgcttatgc cggtatatta
    16921 gttatcttcc ttggcttgac cagccagaat tttggtatgc gtaaccaggg actaaactac
    16981 ggctttatgt attttggttt tgccgtcggt gcggttattg ctccttacgt cacgtccgct
    17041 attgcaaaat ataccggaag ctacaataca gtatttattt tgacaacggt gctattgctt
    17101 attggagtcg tgttgaccct gataacgaaa aaatatgtcg caacggtttt agccaaaatt
    17161 cattaatcag ataataagga aataaaaatg aaaattgcaa tcgcaggtgc aggcgctatg
    17221 ggatgtcgtt ttggctatat gctgctggag gccgggcacg acgtgacgct tattgatggc
    17281 tggcaggagc atgtcgacgc tattcgtagc aaggggttgt ttgtcgaaac ggaaacgact
    17341 cagaagtatt accccatccc tgctatgttg gctgatgaat cccaggggga gtttgagctg
    17401 gttattctgt ttaccaaagc catgcagttg gatagcatgt tacagcgtat taagccgctg
    17461 ctgccagccg cgaaggtcgt gatgatttta tctaacggcc tgggaaatat cgaaaccctg
    17521 gagaaatatg tcgatcggca gaaaatctat gcgggtgtga cgttatggtc cagcgaactg
    17581 gagggggctg ggcatattat ggccaccggt accggaacga ttgaactgca gccgatagcc
    17641 agccaagatt cggctcaaga ggctaaggtc attgccaccc ttaatagtgc tggattgaat
    17701 gctgaaataa gccctgacgt attattatcg atctggaaga aagcagcctt taatagcgta
    17761 atgaacacct attgcgcgtt actggattgt aatgtcggcg gatttggtca gcggcctggt
    17821 gctttagatt tagcgcaagc ggtagttgat gagtttgtgt tagttgctgc cagccagaat
    17881 attccgttga ctgagcaaat ggtgatgaat acggtgaaga aagtgttcga tccgcgtgag
    17941 agcggccacc actatccttc tatgcatcag gatttacata aaggccgact gaccgaaatc
    18001 gactatttaa atggtgcgat tgcgcgaatc ggcgctcaga acaatattgc cgtaccggtt
    18061 aacacactcc tgacgcaatt gattcacgct aaagaagcgc aataaacttg atagctcttc
    18121 tgcatgaggc ggaagagcca ttttcaaacc agttttttta ccagcgcctc gctatggcga
    18181 atacgctccg gcgcccgctc taaatcctgt tgtaccagcg ccataaacag taagtcggtc
    18241 aacatcattt gcgcatgtgt cgaggagata gcggcgctac gcgtcgcctg ctcttcggca
    18301 atcgtataca gacagcgggt ggcgcgctgc tgcaaggcgt tgggagaaaa accggtaatg
    18361 gccaggattt tcgcgcctgc gcgtaatgtt tcgtccgccg ccaggttcag ctcgcgccgc
    18421 tccccggaat aagagatcgc cagcagcaga tcctccggcg ccagcgcctg caccgtcgcc
    18481 agcagggcgt gcatatcgcg ctcaaccacc gcgttaatgc caatcttcag tagcttccag
    18541 gcaaaatttt gcgccaccag cccagaggcg ccaattccgg tgatcacaat acggcgggcg
    18601 tggcgcagca tcgtgacgct ttctaacagc ttttcttcac tgttaacgtc cagcgtggcg
    18661 tgcatcgccg ccacattctc tttaattaat ttttccccga ccaggcgcat cggatcgtcg
    18721 ccgcgaatct ggttatgaac gggaacggaa tgcggattag gattgctggc caacgcttcg
    18781 ctgatagcca gtttcaacgc cggaaaccct ttaaacccca gtttttgcgc gaacttgact
    18841 acgctggatt ggctgacgcc cgcttcggcc gccagttgct gcgagctcag atgtcgcgcc
    18901 gtatccggtt gcgcgagcag ataatccgcc agtttcctgt cgctttgcgc gagatccgga
    18961 taacgctggc gaatacgaat caaacagttc atgggcagct cctgcgaaac gtgatggcga
    19021 cgacaaaacg aaatttcact cgcctggggg aatattctat tccatcatgg acgcttatta
    19081 tgaattaaaa attccagagg gacaaaaatg aatcttggta ccttagtgtc tgaaacccgt
    19141 aacccgcaaa cgatggatct ggatgcgttg tctactcctg aattagttaa gcgttttaat
    19201 gaacaggata cgctggtagc ggaagcagta aaagccactc tgcctgacgt tgcgcgtgcg
    19261 gtggatgctg ctgcggcggc gctgaagtct ggcggacgta tcatctatat gggggcgggc
    19321 accagtggtc ggcttggcgt actggatgcc tcagaatgcc ccccgacgtt tggcgttccg
    19381 cacggtctgg tcgtcgggct gattgccggc gggccgggcg cgttgctgaa ggcggtcgaa
    19441 ggcgcggaag acagccaaca ggcaggcgaa gacgatcttg tcgcgctaaa tctgcaagaa
    19501 caggatctgg tcgtggggct cgcggcgtcg ggtcgtacac cctatgtgat tggtggcctg
    19561 cgctatgcgc gacagtccgg ttgtaccact gttgccgtct cctgtaatcc agattcgcct
    19621 attgcgcggg aggctaatat cgctatttcg cccgttgtcg ggccggaagc gcttaccggc
    19681 tccacgcggc tgaaatccgg caccgcgcag aaaatggtgc tcaatatgat ttctaccggc
    19741 gcgatggtga agttcggtaa ggtctatcag aacctgatgg tggatatgaa agccaccaac
    19801 gtcaaactgg tcgatcgcgc gtgtcggatg gtcgttgaag cgaccgggat aggtcgtgaa
    19861 gaggcggaaa cgttgctgaa acagaccgat tttgaggtta agcccgccat tttgatggcg
    19921 cttacggggc tggatgctgc agccgccagg gaaaaactcg ccgctcatca gggcttttta
    19981 agggcggcgt tagaacacta aagaggtgtg tatggataag acggcagcgc tcgccagcga
    20041 cattttacgt ggtatcggcg gagagcaaaa tattctgcgc ctggaaaact gtatgacgcg
    20101 agtcagagtg gaggtacagg acgacagcca actggatatt ccgcgcttaa aagcgttgcc
    20161 tggcgtcagt ggatacgtaa agcaagggga gcaacatcag ctgatcgttg ggccggggaa
    20221 ggctgcacag gtggttgatg cgatgcgcgt gcagattgcc gcaggtggtg taaagccgga
    20281 cgatgctatg gcgcgtacca aatccgaggc gaaagcgaag tataaagcgc cgatgagcga
    20341 tgcgttgcgt aagctggcga atgtttttat tccgcttatt cccgccttta tcgcatccgg
    20401 cttgattacc ggcattatca atattcttaa acgcccggat atcgtcggcg atgttgccgt
    20461 ccactatcct aacctgctgg gcctgatggg gatatttggt agcgcggtgt tcgctatcat
    20521 gaacattctg gttggcgtca ataccgcgaa agtctttggc ggatcgcagg cgttaggcgg
    20581 cgtgatggcg gggatccttt ccagcccgca actggcgcag attacgctct ttggcgaggc
    20641 gcttcagccg ggacggggcg gcgttatcgc cgtcctgctg gtggtggcgt taatgtgctg
    20701 gattgagcgc cagttccgta agctgctgcc ggggtcgctg gagttaattc ttaacccttt
    20761 attgacgact gttatcaccg gcgcggtagc gattgtcgct ctgcaaccgc ttggcggctg
    20821 gatttcagac gctatcgctc acggcgcgtc ctgggctatc gatcgcggcg gttttctggt
    20881 gggcgcggtg ttagccggaa ccttcctgcc gttggtactg atcgggctgc atcaggggct
    20941 ggtgcctatt catgtggagc tggtgcaagc gcacggctat aacgcgctgt ttcccatcct
    21001 ggcgatggcg ggggttggtc agataggcgc ggccattgcc gtactgatga aaacccgcaa
    21061 tgcgcggctc aaaaaggtga ttaaaggcgc gcttccggtc ggactgctgg ggattggcga
    21121 gccgctgatt tttggcgtca cgctgccatt gggtaagcca tttattggcg cttgcctcgg
    21181 cggcgcggta ggcggggcgt tgatcagcta ctggaaagtg gcgacggtaa ttacctttgg
    21241 tatttccggt ttgccgctgg cattaacaat tgttgccgga aaagtcctgt tctatctgtt
    21301 aggctattta atagcggtaa ttgccgggtt tatttttacc tggctgctgg ggttcaatga
    21361 tccagaggag taaggtttgg tcagccacga gcgtcgtgtc gtcttttttg atttggatgg
    21421 aacgttatat caacaggata tgttcggcag ttttctgcgt tatttgctgc gccgtcagcc
    21481 gctaaatgcg ctgctcgtac tgccgttgtt gcccattatc ggtatcggtt tactggtaaa
    21541 agggcgtgcg gcccgctggc cgatgagtct gttattgtgg ggctgtactt ttggccatag
    21601 cgaaacgcgt ttgcaggcgc atcaggcgga ttttgtccgt tggtttcgcg ctaacgtcac
    21661 ggcgtttccg gtcgtacagg agcgtctgac cacctatcta ttgagctctg acgcggatat
    21721 ctggcttatt accggttctc cgcaatcatt ggtagagcaa gtctattttg atacgccgtg
    21781 gttgccgcgt gttaacctca tcgccagcca gatggcgcga cggtatggcg gctgggtatt
    21841 aaccgtgcgc tgtctgggcc atgaaaaagt cgcgcaactg gaacgtaaaa tcggtacgcc
    21901 gttgcgtctt tatagcggct acagcgacag caaacaggat aacccgctgc tttatttttg
    21961 ccagcatcgc tggcgggtga cgccgcacgg cgagttgcag cagctcgaat agtgaaacgc
    22021 atagcgtctg tgtataatgc cgcccgcttt cattaccgga gttacctctt tgtctgatgt
    22081 cgaattagat cacgaatact ggatgcgcca cgcgctgacg ctggcgaaac gcgcctggga
    22141 cgaacgcgag gttccggttg gcgcggtatt ggtgcataac catcgcgtca ttggcgaagg
    22201 ctggaatcga cccattggcc gccacgatcc tactgcgcat gctgaaataa tggcgctgcg
    22261 tcagggcggt ctggtattgc agaattatcg gttactggat accacgctgt atgtcacgct
    22321 ggaaccctgt gtgatgtgcg caggcgctat ggtgcatagc cgcattggac gcgttgtctt
    22381 tggcgcgcgc gatgcaaaaa ctggcgcggc cggatcgcta attgacgtgc tgcaccatcc
    22441 gggaatgaat caccgggtcg agattattga aggggtgttg cgcgatgaat gtgcgacgct
    22501 gctcagtgat tttttccgta tgcgtcgtca ggaaattaaa gctctgaaga aagccgaccg
    22561 tgcggaaggc gcggggccgg cagtatagcg caatgccgga taagacgttg cgcgtcgcca
    22621 tccgataaga ccatcgcgct atttttcttc tttcttctgc ggcgtaaaca gtaaagacgg
    22681 cgaatgcgtc aggtagcctg atgactgcga taaaaacgac aggaagggga agggggcttt
    22741 attcagctcc tccggctaca ccgccgggta atcctgcgcc agtttcatag cttccgcttc
    22801 ctgcttttct ttttcctgca aataccccac caaacttatc tggtatttac ggatattttc
    22861 cacataagca taagcctcat gtccacgcgc gtaaccgtag gttagcttac tgtaatacgg
    22921 tttttggctt aacagaggca aacgctgctt cacatcggtc cagctatccg gattgccttt
    22981 ggtttttacc gtcagcgatc tggcatcgag catgtgcgca taacccatat tgtaggcggc
    23041 taaggcaaac cagatacgct cgtcttccgg aacggtttcg ggaactttag ccatcatatc
    23101 ttcaagatag cgagcaccgc cgctgatgct ttgctccgca tcggtacggt cggtcagccc
    23161 cagactttgg gcggtatttt tagtcagcat catcaggccg cgcacgccgg ttggcgaggt
    23221 cgccagcggg tcccagtgtg attcctgata agaaatcgcc gccagcaggc gccagtctat
    23281 ctctttggca tattttttaa ataacggttc cagctccggc aggacgttat ccaccgctcg
    23341 caggaaagag cgggtatcaa cgtagtcgaa atcatcgcca tgccccagat atttctcttc
    23401 gatccgcgcc aacgacccgt cttcattgat cgaattgaaa aaatcgagca gcgcggcgga
    23461 gagcgtatta tcgtcgtcca gtcggctaaa ccaggtcacg ggctgttcat ccgtgacatc
    23521 cagcgccacg gccagttcgg gatggacgcg ctgaaacaga ctgatcgcca ctgaatcggc
    23581 aatggtgtaa tccagtttgc cgctgatgac ctcttccagc agcgtcgtcg agcctttttt
    23641 atcatccacc ttccagctca ggtcgggaaa ctttgtctct tttaaacgct gtaaatcatt
    23701 gaccacgacg tgccctggcg caatggtaag ctgattctcg ttaacggtcg ccagcgaacg
    23761 tgggcgatat tgtccgaccc ggtaaacgag ctgttgcgaa accgaataat acatggggcc
    23821 gggctgatag tttttaacgc gcgcgctgtc gtagaccagc cctgccgcga gcaggtcggc
    23881 attgccgtta tccagatcgt caaacaactg gctgatattc tggcgcaccg tcactttcag
    23941 cttcacgccg agatagttgg cgaactgctg cgccagttca tagtccagac catatttttt
    24001 accgttgata acggaatagg ttaatggcga gtcgatcgta ctgacgcgca gtaccccccg
    24061 ggcttgaatc gcggcgatat ggttttcggt tttaccgaac caggggattg agggccaaag
    24121 ggctgctgcc agcagcagcg tcaatatgcc gatgaacaga taattaatct ttaatttttt
    24181 caattagtta attctctgga tcgtgcgttg cctcgggctg aaaaagatgt tttgctgcaa
    24241 tagataagtc actaatgagc ggcattttgc gtaacaatgc gccagttggc aacttattcg
    24301 caacgatagc cgcaccgtat gacaagaaaa agcggtgatt ttatttctac gcaaacggtt
    24361 tcgtcggcgc gtcagattct ttataatggc ggccgtttcc ccccttgcgc acaccgaagc
    24421 ttagaagacg agagacttat gatggaaatt ctgcgtggtt cgcctgcact gtctgcattc
    24481 cgtatcaata aactgctggc gcgctttcag gctgccaacc tccaggtcca caatatatac
    24541 gctgagtatg tccattttgc tgacctgaac gccccgttaa atgatagcga gcaggcgcag
    24601 cttacccgtc tgctgcaata cggcccggcg cttagcagcc atacgctggc gggtaaactc
    24661 ctgttggtca caccgcgtcc tggtaccatc tccccctggt cttcaaaagc aacggatatc
    24721 gcccacaact gcggcctgca acagattgac cgtctggagc gcggcgtagc gtactatatc
    24781 gaggcttcga cgttgacggc ggaacagtgg cgacaagtgg ccgcagagct gcacgaccgt
    24841 atgatggaga cggtgttctc ttctttaacc gatgcggaaa aactgtttat ccaccatcag
    24901 cctgcgccgg tttccagtgt cgatctgctg ggagaaggcc gtcaggcgtt aattgacgct
    24961 aacctgcgtc tcggtctggc gctggcggaa gatgaaatcg actatttgca ggaggcgttt
    25021 accaaactgg gacgcaaccc gaacgatatc gaactgtaca tgttcgccca ggcgaactcc
    25081 gagcactgcc gccacaagat ttttaacgcc gactggatta tcgacggtaa accgcagccg
    25141 aagtcgctgt ttaaaatgat taaaaacacc ttcgaaacca cgccggacta tgtgctctct
    25201 gcctataaag acaatgccgc ggtgatggaa ggatctgcgg tggggcgcta cttcgccgac
    25261 cacaataccg gccgttacga ttttcatcag gagcccgcgc acattctgat gaaggtcgaa
    25321 acgcataacc acccaaccgc catctctccg tggccggggg cggcgaccgg ttccggcggc
    25381 gaaattcgtg atgaaggcgc caccgggcgt ggcgcgaaac caaaagccgg gctggtaggc
    25441 ttctccgttt ccaacctgcg tattccgggc tttgaacagc cgtgggaaga ggattttggc
    25501 aagccggaac gtattgtcac cgcgctggat atcatgaccg aaggtccgct gggcggcgcg
    25561 gcgtttaaca acgaatttgg tcgcccggcg ctgaccggtt acttccgtac ttatgaagag
    25621 aaagtgaaca gccacaatgg cgaagagctg cgtggctatc acaagccgat catgctggcg
    25681 ggcgggatcg gtaatatccg cgccgatcac gtgcagaaag gcgagatcgt cgtaggcgcg
    25741 aagctgatcg tccttggcgg cccggcgatg aatatcggcc tcggcggcgg cgcggcatcg
    25801 tcaatggctt ccggccagtc tgatgcggat ctcgattttg cctctgttca gcgcgacaac
    25861 ccggaaatgg aacgccgctg ccaggaagtg atcgaccgct gctggcagtt gggcgacgct
    25921 aacccaatcc tgtttatcca tgatgtgggc gcgggcggtc tctccaacgc catgccggag
    25981 ctggtaagcg acggcgggcg cggcgggaaa ttcgaactgc gcgacattct tagcgacgag
    26041 ccgggcatga gcccgctgga aatctggtgt aacgaatccc aggagcgcta tgtgctggcg
    26101 gtcgcggctg accagttacc gctgttcgat gaactgtgta agcgcgaacg cgcgccgtat
    26161 gcggtcattg gcgacgctac cgaagaacag catctctcgt tgcatgataa ccatttcgac
    26221 aatcagccga tcgatctacc gctggatgtc ctgctgggca aaacaccgaa aatgacccgc
    26281 gatgtgcaaa cattgaaggc gaaaggcgat gcgctgaacc gcgcggatat cacgattgcc
    26341 gacgcggtaa atcgtgttct gcatctgccg accgtggcgg aaaaaacctt ccttgtcact
    26401 attggcgacc gtaccgtcac cggtatggtg gcgcgtgacc agatggttgg cccgtggcag
    26461 gtcccggtag ctgactgcgc ggtcactacc gctagcctcg acagctacta cggcgaagcg
    26521 atgtcgattg gcgagcgcgc gccggtggcg ctgctggact ttgccgcctc cgcccgtctg
    26581 gccgtcggtg aagcgttgac taacattgcc gcgacgcaga ttggcgatat caagcgcatt
    26641 aagctttccg ctaactggat ggcggcagcc ggtcatcctg gcgaagatgc cggtttgtat
    26701 gacgcggtta aagcggtggg agaggaactc tgtccgcagc ttggcctgac gattccggtg
    26761 ggtaaagatt cgatgtcgat gaaaacccgc tggcaggaag gcaacgaaca gcgcgaaatg
    26821 acctcgccgc tgtcgctggt gatttccgcg tttgcccgcg tggaagacgt gcgtcacacc
    26881 cttacgccgc agctgtcaac ggaagataac gccttgctgc tgatcgatct tggcaagggc
    26941 cacaacgcgc tgggcgcaac ggcgttggcg caggtctatc gtcagcttgg cgacaaaccc
    27001 gcggacgtgc gtgacgttgc gcaactgaaa ggcttctatg acgccatgca ggtgctggtt
    27061 gctgcgcgta aattactggc atggcacgac cgttccgacg gcggtctgct ggtgacgctg
    27121 gccgagatgg cctttgccgg ccactgcggc gtgcaggtcg atatcgccgc gctgggcgat
    27181 gaccatctgg ccgcactgtt caacgaggag ctgggcggcg tgattcaggt acgcgctgaa
    27241 gacagagacg cggtcgaaac gctgttggcg cagtacggtc ttgctgactg cgtccactac
    27301 cttggtcagg ccctggctgg cgatcgcttt gtgattaccg ctaatgatcg gacggtattc
    27361 agcgaaagcc gtactacgct gcgtgtctgg tgggcggaaa ccacctggca gatgcagcgt
    27421 ctgcgcgaca atccgcaatg tgctgaccag gaacacgagg cgaaagcgaa tgatgccgat
    27481 ccgggcctca acgtgaagct gtcgtttgat attaatgaag atatcgccgc gccgtacatt
    27541 gcgacaggcg cacgaccgaa agtcgctgta ctgcgcgagc agggggtgaa ctctcacgtg
    27601 gagatggcgg cggcgttcca tcgtgcgggc tttgacgcga ttgacgtcca tatgagcgac
    27661 ctgctgggcg gtcgtatcgg tctgggcaac ttccatgcgc tggtggcttg cggcggcttt
    27721 tcctacggcg acgtgctggg ggcgggcgaa ggctgggcga aatccattct gtttaaccat
    27781 cgggtgcgcg acgaattcga aaccttcttc catcgtccgc agacgctggc gctgggcgtg
    27841 tgcaacggtt gccagatgat gtcgaatctg cgcgagctga tcccgggcag cgaactgtgg
    27901 ccgcgttttg tacgtaacca ttctgaccgc ttcgaagccc gcttcagcct ggtggaagtg
    27961 acgcaaagcc catcgctgct gctgcaagga atggtaggct cacagatgcc gattgcggtt
    28021 tcccatgggg aagggcgcgt tgaggtgcgt gacgatgcgc atcttgccgc gcttgagagc
    28081 aaaggcctgg tcgctctgcg ctacgttgat aactttggta aggtgaccga aacctatccg
    28141 gctaacccga acggttcgcc gaacggcatc acggcggtga cgaccgaaaa cggtcgggtg
    28201 acgattatga tgccgcatcc ggaacgcgta ttccgcaccg tcgccaactc ctggcacccg
    28261 gaaaactggg gcgaggatag cccgtggatg cgtatcttcc gtaatgcgcg taagcagctt
    28321 ggttaattag cccgatagcc attaagcccc tcttcacgag gggctttttt gtagacggcg
    28381 cttatcaggc ccacggggaa gcgcggttgt agctaccgtc ttgaacgtca agcggtaggg
    28441 cggataaggc gtttacgccg ccatccggca ataaactagc gcttatgccg caagattaaa
    28501 gtgtcgggaa atcccgacat gagtggggat aggttgtcgc caaaaagaga catttaacta
    28561 tttgatttta aatgatttta tttttaggtg ttgcaggtgt tgctgattga cgacagaaag
    28621 gacaaaaaaa cagacagagc catttttagc atgaataacg atatttttca tatctatcat
    28681 tgtgttaaca aagtcttttg aatgttggca caattactgc ataatggtaa ccagtggctc
    28741 attcaccttc ttatgtcagc cccttaggga cgcgctacat aaacttcgaa tgacgcacaa
    28801 caaggtgcct gccgtctaac ttctgataat agcgtagctt tatcaacctc cgggcgaaac
    28861 gtcgagttag gcaccgcctt attccataac aaagccgggt ttagcccggc tttgttgtat
    28921 ctgacgctcc cctcggttag catctttttt attcttcttt ttatgtgagc gacacgttga
    28981 agcgctggtc tgttttcccc cgttctttac gacaattggt catgctggcc tttttgctga
    29041 tcctgctgcc gttgctggtt ctggcctggc aggcgtggca aagccttaac gcgttaagcg
    29101 atcaggctgc ggtgactaac cgcagcacgc ttattgacgc ccggcgcagc gaggcgatga
    29161 ccaacgtcgc gctggagatg gagcgaagct accgacagta ttgcgtgctt gacgatccga
    29221 cgctggcaaa agtgtatcaa agccagcgta agcgctatag cgatatgctg gatgcccatg
    29281 ccggcgtctt gccggatgat aagttgtatc aggcgttacg ccaggattta aacgcgctgg
    29341 cgcaattgca gtgtaaagat agcggcccgg aagcggcagc ggccgcgcgt ctggaggcct
    29401 ttgccaacgc gaatacggaa atggtgcagg cgacgcgtac tgtggtttac tcgcgcgggc
    29461 agcagttaca acaagaaatc gccgagcgcg gacaattttt cggctggcag gcgctggtgc
    29521 tatttctggt gagcctggcg atggtgctac tttttacccg catgattatc gggccggtga
    29581 aaggaattga acggatgatt aatcgcctgg gcgaaggccg ttctttgggg aataccgtca
    29641 cctttaccgg tccgcgtgaa ttacgatcgg tggggcagcg cattatctgg ctgagtgagc
    29701 gtctggcgtg gctggaatcc caacgccatc agtttctacg tcacttgtcc catgagctga
    29761 aaactccgct ggccagtatg cgcgagggga cagagctgct ggccgatcag gtggttgggc
    29821 cgctgacgcc ggagcaaaaa gaggtggtcg atattctgga tgacagcagt cgtaatttac
    29881 aaaaattgat tgagcaattg cttgattaca accggaaact ggtagacagt gccacagagc
    29941 tggaagcggt cgatatcgcg ccgcttgtgg atatggtggt ttccgcccac agtttgcctg
    30001 cccgcgctaa aatgatgcat accgatgtcg acctggaggc cgaacgctgc atagcagagc
    30061 ccatgttgct gatgagcgtg ctggataatc tctattccaa cgctgtgcac tatggcgctg
    30121 aatccggtaa catttgtatc cgtagtcgct ctcagggctc cacggtttat atcgatgtgg
    30181 ttaatagcgg cgaaccgatt ccgcaaaccg aaagagaaat gatttttgag ccttttttcc
    30241 agggaagcca ccagcgaaaa ggggcggtaa aaggcagtgg gttagggctg agtatcgcca
    30301 gagattgtat tcgtcgaatg cagggagaga tccagctggt ggatgacaaa gcgcaggaag
    30361 tttgttttcg catctcgctg ccattgcctg catctgacaa acactaatat gaatttaagc
    30421 ctggtgcgta tgtcacacgt tttcgtccaa actattaaac gatgcctttt gcgatgggga
    30481 ataccggtgg gcatatcgtg tctggcgctg accgcatgtg ttccccatgc ttcacagcaa
    30541 ctgcccggta gcgcagcgca ggacacgctc ccccattatc aactggcgga ttatctcccg
    30601 acggcgtgcg cggatatctg gtcgctacgc gggcaggcgg tggagacgaa tccgctgtac
    30661 tggctacgca cgattgactg cgccgatcgt ctgatgccgg ttcagtcgcg cgcagaggcg
    30721 cgcgcgttga cggatgataa ctggcagaat gccttcaggc gcgggatttt actggcggat
    30781 gcaaaaatta cgccgccgga gcggcgcgcc atagtgaccc gtctggaggc gttaagcgcg
    30841 caaataccgg ctcaggtacg gcccgtctac caaatctggc atgacggtca ggcgctgcaa
    30901 ttagcgcttt ctgccgaacg tcagcgttat agcaaactcc agcaaacgtc agatagtgag
    30961 ctggatgcgt tgcgccagca gcaacaggcc ttgcaaacgc agctcgatct tactacccgt
    31021 aagctggaga gtttaaccga cattgagcgc cagctttcga cacgaaaacc ggcagggaat
    31081 tacaacgccg atacgccgca tacgaatgac aaacccgcga cgtctgaaga tggcgcggcg
    31141 ccgtcgccgt cacaagatga ggtaacgcca tgataagccg taaaccggcg cacctgctgc
    31201 tggtcgatga cgatcccgga ttactgaaat tgctcggtat gcgcctgacc agtgaaggat
    31261 acagcgtcgt gaccgcagag agcggccagg aaggactacg ggtactgcat cgggaaaaag
    31321 tggatctggt aataagcgac ctgcgcatgg acgaaatgga tggtatgcaa ctgttcacag
    31381 aaattcagaa agtacagccg ggaatgccgg ttattattct gacggcgcat ggttctattc
    31441 cggatgcggt ggccgctacc cagaagggcg tattcagctt tttgacgaag ccgatcgaca
    31501 gagacgcgtt atataaagcg atagatgaag cgctggagca gtccgctccc gcgacggacg
    31561 atagctggcg caacgctatc gttacccgta gcccgctgat gctgcgactg cttgaacagg
    31621 cgcgcatggt cgcgcagtcg gatgtcagcg tattgattaa cggacaaagc ggcaccggga
    31681 aagagatttt cgcacaggcg attcataatg ccagcccgcg caataacaag ccgtttgtcg
    31741 ccatcaactg cggcgcgtta ccggaacagt tgctggagtc cgaattattc ggccatgcgc
    31801 gcggcgcctt taccggcgca gtgagcaatc gtgaagggtt gttccaggcg gcggaaggcg
    31861 gcacgctgtt tctggatgaa attggcgata tgcccgcgcc gttacaggtg aagctgctgc
    31921 gggtgttaca ggagcgcaaa gtcaggccgc tgggcagcaa tcgcgatatt gatatcgacg
    31981 tgcgaattat ttccgcgacg caccgcgatc tgccgaaggc gatggcgcgg ggcgaatttc
    32041 gtgaagattt gtactaccgg ctgaatgtcg tgagcctgaa aattccggcg ctggcggagc
    32101 gtaccgagga tattccgctg ctggctaatc atctgctcag acagtcggca cagcggcata
    32161 aaccgtttgt tcgcgccttt tctactgatg caatgaaacg gctgatgacg gcaagctggc
    32221 cgggcaacgt gcgccaactg gtcaacgtca ttgaacaatg tgtggcgtta acctcttcgc
    32281 cggtgatcag cgatgcattg gtcgagcagg cgctggaagg cgaaaacacc gcgctgccaa
    32341 cttttgccga agcgcgaaac caatttgaac tgaactatct gcgcaagtta ctgcaaatta
    32401 ccaaaggtaa cgtgacgcac gcggcaagga tggcggggcg caaccgcacg gaattctata
    32461 agctactctc ccgtcacgaa ctggatgcga atgatttcaa agagtagttt tcatgccgta
    32521 aagtagcgcg aaatatgtta cgtttaaccg atcaaaacac aggcgacctt ttcaaggaat
    32581 agcatgaaaa agattgatgc gattattaaa cccttcaagc tggacgatgt ccgtgaagcg
    32641 ctggccgagg taggtattac cggtatgacg gtcactgaag tcaaaggctt tggccgtcaa
    32701 aaaggccaca ccgagctgta tcgcggcgcg gaatatatgg tggattttct gccgaaggta
    32761 aaaattgaaa tcgttgtgcc tgacgacatc gtggatacct gtgttgatac catcattcgt
    32821 accgcgcaga cggggaaaat cggcgacggt aagatctttg tctttgatgt cgcccgcgtt
    32881 attcgtatcc gtactggcga agaagacgac gcggctatct gatgtgccga ttcgctgccc
    32941 gtctcctcct tgtgggcagc gaaccaccgt ttaatcgccc tgcggtagcg ccgatgtagt
    33001 ccgggtgcaa atccatctca ggccgacaat ggcgacgatc agcgccacgc aacttagtgt
    33061 ccactcgctc atttgcgaga aaaagtgtcc gtaggcggct accgccgtat cactaatttg
    33121 cgattccgtg gtttgttgcg cgacgacgcc agccagccag ttagcgatcg cgccggtcgc
    33181 cagcatataa ataccggtca gtacgcccgt gacgccaggc agattgaggc gggtaatttg
    33241 cgccatcgcg accggatcaa taaacagctc cgcaaagccc atcagcgcca gccctgcgat
    33301 catcattccc attgatgcct gcccatctaa ccgggcctga tgcgcgttta gcgccagcag
    33361 cataaaaccg ccgcccatta atatcagccc cacggcaaat ttaagccaga cgcgcagcac
    33421 cgagcgggcg ctctctttcg ggctgctcag ccacgccagc accacgcccg ccgccatcac
    33481 cgcaatcgca ttgaccgact ggaacaatgc ggtggggacg gtcatattca gccagtggcg
    33541 gttgacaaaa cggtcgatga ataaactgat cgaacttccg ccctgctgcg ccagaaccca
    33601 aaagagagtg ccggtgatca ttaacagaac gatttgccac aaggcgcgac ggtgttcggg
    33661 aaatttaacc ataatacggg cgataagttg cgccgcgaag acgcagacaa tggccagcac
    33721 atagccagac cagttatttt ccagcaggag ggtgaagaat accggcgcga tacacagcat
    33781 taataccagc caaccccagg ttggaagggc gaatttaacc gcccgcagcg cggggcgatt
    33841 aacaccgcgc gtctgctgaa agtggcgatg accgcttaaa aagatgagca ggccgatgaa
    33901 cattccgacg cccgccagcg caaagccgac atgccagcca taccactgcg ccgccagacc
    33961 acaggcgatc ggcgcggcta tcgatccaat attcccggcg gcgtagagca gcgagaatcc
    34021 cccgtcgcgg cggttgtcat caggggcgta aagttcgccc agcagacagc taatattgga
    34081 tttaaacaag ccgtagccgc agataataat ggccagcgcc gcatataaac tcagcgttga
    34141 atcagattct aagcccaata ccacatgacc cagcgtcatc aataaggcgc cggtgataac
    34201 cgccacgcgg ttgccaagca ggcggtcggc aagccagccg ccaagaatag gggtaacgta
    34261 aactaaagag gcgtaggcgc tgaagaggtt gatcgcgtgg ctgtcattaa aaccaagctg
    34321 gtgggtaaga taaaggatga gtaaggcacg catgccgtaa aagctgaagt attcccaaat
    34381 ttgaatcgcc acgatgtaaa aaatcgcgcg cggttgtgag ggtgttttca taaagtctcc
    34441 ttgctgcgtg aaaaaaggga agtggcaagc cacttccctt tggtacttat ttcgtatttt
    34501 ctttcagcac cttaacggtg taacgtccgt cagcctgacg ataggcgccg tggatatcgg
    34561 tttcgaagcc cggatagtga gcgccgattt cgcacagcat ttgcaggaat tccagtaccg
    34621 gacggctttc ctcggtgatc atttcaccag gcatcaccag cggcactccc ggagggtaag
    34681 gaaggatcat gttggcgttg acgcgtccaa ccatctcttc aagatacacc tcttccgttt
    34741 cgccatgcag ctctttctgg aacgcagtat acggcgtcat caccattttc ggcagcactt
    34801 caaacgcacg gtacattaag tccggcagat tatgatgttc gaccagttta tgaatattct
    34861 gcgccagttc ctggatgcgc atattttcat aaaactcagg cgcttcgcga tacagtgccg
    34921 gcagaatgtt tttgacgcgc aggttcaggt caaaggcgcg tttaaattca gtgagcgcgc
    34981 gcagcaggct cagagctttg gttttgtcga taccaatgct gaacaggaac agcaggttgt
    35041 atggaccggt tttttctacg atgatgccgc gttcatcgag atatttggcg accagacttg
    35101 ccggaatacc gaattcatcc atcgtaccgt ctttcttcat ccccggcgtc aggatagtga
    35161 ctttgatcgg gtcgaggtac atgtgttcgt tatcgatatt tttgaagcca tgccatgcgc
    35221 tatctgaacg cagcggccag cactcagctc catcgatatg ttccggctgc catacgtcaa
    35281 agaaccagcc gtcagattcg cttttcaggc gtttaatttc tttacggaat ttaatcgcac
    35341 gttcaataga gccgttaatc aggcgtttac ccgcattacc tttcatcatc gccgctgcgg
    35401 tttcagtaga cgctacgata ccgtagtgcg gagaagtggt ggtatgcatc atgtaggctt
    35461 cgttaaaggt ttcttcgtta atgtcgcctt taacatgaat catggatgcc tgtgaaaacg
    35521 ccgccagcag tttatgcgtg gactgggttt cataaatgat tttgccttct acacggtcgc
    35581 cgctcatacc gcatttaccc tgataaatag gggagaaatt ggtgtaaggc acccaggcgg
    35641 agtcaaaatg aatggacttc acatccagag ttttcttgat gtagtcagtg ttatacaaca
    35701 gaccgtcata ggttgagtta gtaataacag catggaccgg ccaggtggcg ttaggcgtct
    35761 cttttacccg tttagcgata gtggcgtgct ggaactcgct ttgcggaata ccgccaagaa
    35821 taccgtaggc gttacgggtt gggcggaaat aaatcggcgt aatgtcgctc atcatcatca
    35881 gatgggtcag cgatttatgg cagttacggt caatcagtac cgtgctgcct gccggcgcgg
    35941 agtacatacc gacgattttg ttcgccgtag aggtgccgtt cgtcaccatg tagctacgtt
    36001 cggcgttaaa gacgcgggcg atatactctt ccgcttcttt atgcgggccg gagtggtcca
    36061 gcagcgaacc cagttcggaa acggaaatcg aaatatcgga tttcatcgtg ttcgggccga
    36121 agaaatcata aaagatgctg ccgacggggc ttttctggaa agcagtaccg cccatgtggc
    36181 caggcgtaca gaaagtgtat ttcccttcgc gcacatattt gaacagtgct tttgtcagcg
    36241 gcggcagaat attgtcgatg tattcatcgg tattctggcg aattttcgcc gcgatatcgg
    36301 ctgcggcgcc taaagcatat tcaaagaagc gaacctgcat tctcagatcg ttgaggctga
    36361 cgtccagcgt agagtagctg ttggcgaagg catacagcgg catatactcg ttcagcttgc
    36421 taatctcttc gcaaagctca aggttatatt tatcccagtc gaaaatgacg ccgcaaaggc
    36481 gggagttatt ttcaatcagc ttcagcaggt cttctcggtc gtttggatag acgatacgga
    36541 aatttaaacc ttccagtgca cgatgcagtt cacgaatagg ctcttcttta aagtagacgc
    36601 ccatgtggtt catgatagca ataacgttca tagtcttgtt cctggtaaag tgggcccctc
    36661 ccgctacgct atagcaggtg acgaaagggg ctttgagaaa aaggagttag cggttaaagc
    36721 gcttcagccg tattgttgtc gctgtcgttg ttctggcgct ggtgcatttt gcgaccgtag
    36781 aacatcagga tgatcagact gacgataaag gtgccggaga gttcgaagga gctggcgccc
    36841 atcagtgcga tgaagcaaaa tgcgcagccc agtacagaac aaatcaggct taccgagtta
    36901 cggatgttga acccttcgaa acgaatcagg tcaacacaag agtagaagta cggcagcatg
    36961 gtaagcagta cggcaatccc ggtcagttcg ccgaacaggt cggacgcttt accgccgctg
    37021 gagttcatga tggtgatcag aatcatcagc gccgtcattt tcaccgcagc caacagcaga
    37081 ccttttttcg gaataccgtt tttatccatt tcaccgtaaa ttttcgggaa gttgccgtcg
    37141 ttggcggcgc gaaccccagc ctggccgacc agcatcatcc aggagcccag agacgtcagg
    37201 caggcgaaag cggtaaaggc ggaaaccagc ggcgcagccc agccacccag aatcgtggag
    37261 gtactgatag cgaacggcgc gccggaagag gccataacgg aagctgggaa catcccggcg
    37321 ataacctgag tcgcggcgat atagatgatg cctgccagcg cggtacccag catggttgcc
    37381 agcggtacgg tgcgtttcgg gtttttcacc atgccggtgc tgacggcggc agactcaacg
    37441 ccaacgaacg cccacaggca gagcagaata cttttaacaa tggcgtgaga gtcggtcgtc
    37501 gtagacgtgt tccagttcgc gtgataggtc gcgatagcga accaatgcca gccggcgact
    37561 gcggtcaaga ctaccgggat cagcaccaga aacaggccaa tcgttgtcaa gcggctgacc
    37621 caggccccgc ccagcatatt aataaaggtg aacagccaga cgatagcaat acaggcaata
    37681 cctgccggta ttggattatt taatgccggg aagaacgtag aaagataaga aaccgcggta
    37741 ataccgatgg ctaagttacc aatccagttt gcgtgataat aaagaacgcc ggtctggaaa
    37801 ccaaacgccg gagatatttc cccagcataa gcgatagggc caccctgttg cgggtttttg
    37861 gttgccagcc tcgcataaac ataagccagc gacattgccc caataataga aattacccag
    37921 ccccagatgg caatgccacc aatactggca aggttggcgg gtaataatgc aatcccgctc
    37981 cccatcatat taccggcaac gacgccagta caggcaaata gcccgatctt tttgacagaa
    38041 ctcatgttca tttctcctga gctgtatttt taagaaccgg gcttatgctt catatatgct
    38101 gcgtgcccgt tcaactgtcg
//
LOCUS       DAJVKX010000034        37396 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000034 DAJVKX010000000
VERSION     DAJVKX010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 37396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37396
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.034"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            135..605
                     /locus_tag="OPY25_001711"
     CDS             135..605
                     /locus_tag="OPY25_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HCS0927345.1"
                     /translation="MKKQQGYTLIETVVAMSLIIILSATGLYGWQRWQQQQRLWQTAC
                     QVRDYLLQLREDAHWHNRDHILRVVSEGGSWCFVSSVATQTSCTPSSPFVFTPDWRDV
                     VLADITPSLAFFGLRNTAWAGHIVLKNAAGEWRLVVSSWGRIRLCERNEAATCQ"
     gene            596..1159
                     /locus_tag="OPY25_001712"
     CDS             596..1159
                     /locus_tag="OPY25_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HCS0927346.1"
                     /translation="MSITTRGFSLLEVVLAMAIGSILLLGSARFLPALQREIWHNTRQ
                     LSLEDEIWQRTYTVAKHLQRAGYCHGHCIGEGLHLAEQGQCVIVQWDGNNNGVWDTIP
                     AKEADQTGFRMKDNVLETLRGATSCQGKGWEKMTDPNTVLITAFNVERRDITGFSPVL
                     MLHLRGASKAEPQTVIDAQYSVTGFNL"
     gene            1156..1563
                     /locus_tag="OPY25_001713"
     CDS             1156..1563
                     /locus_tag="OPY25_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HCS0927347.1"
                     /translation="MNRERGASSLILALLILILGSLLLQGVNQQQASYAARVTTQSMA
                     IQRQALVQSALEWGRGQLWSGVTEMECRRYSSSGARVCLRRLSGDEVVMAAQDDGMTL
                     WRLGNVIQGSIVFSPHGWSDFCPLKEVALCRIP"
     gene            1548..1868
                     /locus_tag="OPY25_001714"
     CDS             1548..1868
                     /locus_tag="OPY25_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCS0927348.1"
                     /translation="MSHPLNFQRGFSLPEVLVAMVLMVMIVTALSGYQRVLMHTFALR
                     HQYLQIWRQAWQQTALYPFSPADGWNANRMQTTQSGCVSISVTMVSPSGRQGQMTRLH
                     CPNR"
     gene            1884..5255
                     /gene="recC"
                     /locus_tag="OPY25_001715"
     CDS             1884..5255
                     /gene="recC"
                     /locus_tag="OPY25_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461913.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HCS0927349.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIAFPLPASFIWEMFVRVLPDIPKESAFSKQSMSWKLMTLLPQL
                     LDKDEFVLLRHYLTDDTDKRKLFQLSARAADLFDQYLVYRPDWLTQWEAGKTVEGLGE
                     AQNWQAPLWKALVEYTAALGQPRWHRANLYQRFIQTLESATACPPGLPSRVFICGISA
                     LPPVYLKALQALGKHIEIHLLFTNPCRYYWGDIKDPAWLAKLMARQRRHSFEDRHLPL
                     FRENQNPEALFNSDGEQDIGNPLLASWGKLGRDYIYLLSELENSQELDAFVDITPDNL
                     LHRIQADILELESHAVAGVNLEEYSRSDNKRLLDPEDNSLSFHVCHSPQREVEILHDR
                     LLAMLEADPTLTPRDIIVMVADIDSYSPFIQAVFGSAPTERYLPYAISDRRARQSHPV
                     LQAFISLLSLPDSRFVSEDVLALLDVPVLAARFTINEEGLRYLRLWVNESGIRWGIDD
                     DNVRELELPATGQHTWQFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNDFFLPDADTEAAMTLIEQQWQAIIAEGV
                     AAEYGDAVPISLLRDELAQRLDQERISQRFLAGPINICTLMPMRSIPFRVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPMRGDRSRRDDDRYLFLEALISAQQTLYISYIGRSIQDNS
                     ERFPSVLVQELVDYIGQSHYLPGDETLTCDESEARVKAHITRLHTRMPFDAQNYQPGE
                     QQSYAREWLPAASQSGKAHSDFVQPLPFTMPETLTLESLQRFWAHPVRAFFQMRLQVN
                     FRSEESEIPDAEPFELEGLTRYQLNQQLLNTLVEEDDAERLFRRFRAAGELPYGAFGE
                     IFWDAQCQEMQQLASRVIACRKPSQSLEVDLLCNGVQLTGWLPQVQEDGLLRWRPALI
                     SVAQGVQLWLEHLVYCASGGSGESRLFLRKEGEWRFPPLDKTQAMAYLAQLIEGYREG
                     MSSPLLVLPESGGAWIKACYDAENDVMLDDDDTLQKARTKFLQAYEGNMMVSGEGEDI
                     WYQRLWRQLESETLQAIIAQSRHYLLPLFRFNQSR"
     gene            5433..8321
                     /gene="ptrA"
                     /locus_tag="OPY25_001716"
     CDS             5433..8321
                     /gene="ptrA"
                     /locus_tag="OPY25_001716"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HCS0927350.1"
                     /translation="MPRSTWFKALLLLVALWGPAVQADIGWQPLQETIRKSDKDTRQY
                     QAIRLDNDMVVLLVSDPQAVKSLSALVVPVVSLEDPEAHQGLAHYLEHMCLMGSKKYP
                     QADSLAEYLKRHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAAPLLNKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSHFSGGNLETLSDKPGNPVQQAL
                     IAFHEKYYSSNLMKAVIYSNKPLPELASIAAATYGRVPNKQIKKPEITVPVITEAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAQFRSKTDELVSYLIGNRSPGTLSDWLQKQGLVE
                     GISADSDPIVNGNSGVFAISATLTDKGLANRDEVVAAIFSYLNTLREKGIDKRYFDEL
                     AHVLDLDFRYPSITRDMDYVEWLADTMIRVPVAHTLDAANIADRYDPAAIKNRLAMMT
                     PQNARIWYISPQEPHNKIAYFVDAPYQVDKISEQTFKNWQQKAQGIALSLPELNPYIP
                     DDFTLIKNDKNYVRPELIVDKADLRVVYAPSRYFASEPKADVSVVLRNPQAMDSARNQ
                     VLFALNDYLAGMALDQLSNQAAVGGISFSTNANNGLMVTANGYTQRLPQLFLALLEGY
                     FSYDATEEQLAQAKSWYTQMMDSAEKGKAYEQAIMPVQMISQVPYFSRDERRALLPSI
                     TLKEVMAYRNALKTGARPEFLVIGNMSEAQATSLAQDVQKQLAANGSAWCRNKDVVVE
                     KKQSVIFEKAGSSTDSALAAVFVPVGYDEYVSAAYSAMLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSYLWQRYQAFFPDAEAKLRAMKPEEFAQIQQ
                     AIITQMRQAPQTLGEEASRLSKDFDRGNMRFDSRDKIIAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQIAGSQNGKAEYVHPTGWKVWDNVSALQQTLPLMSEKNE"
     gene            8314..11859
                     /gene="recB"
                     /locus_tag="OPY25_001717"
     CDS             8314..11859
                     /gene="recB"
                     /locus_tag="OPY25_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HCS0927351.1"
                     /translation="MNDVAETLDPLRLPLTGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATEELRGRIRSNIHELRIACLRESTDNPLYARLLE
                     EISDKKQAAQWLLLAERQMDEAAVFTIHGFCQRMLSLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPRDIAQVVFDVWKGPKALLKDIDRYLQGEAPVIKAPPSQEETL
                     ASRHEQILARINQVKQQWCEAVSELDALIESSGIDRRKFNRGNQAKWIEKITAWAQEE
                     TKNYQLPEALGKFSQRFLAERTKAGGVTPQHPLFVAIDNLLGEPLSIKDLVLTRALSE
                     IRETVAQEKRRRGELGFDDMLSRLDTALRSESGEALAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWRHQPDTALLLIGDPKQAIYAFRGADIFTYMKARSEVSAHYTLDTNWRSA
                     PGMVNSVNKLFSQMNDAFMFRDIPFSPVKFAPRNQSLQFKVNDAPQPAMTLWLMEGES
                     CGSGDYQSYMAQVCATQIRDWLRAGQTGDALLTNGDSSRPVRASDISVLVRSRREAAL
                     IRDALTLLAIPSVYLSNRDSVFETLEAQEMLWVLQAVMAPERENTLRSALATSMMGLT
                     ALDIETLNNDENAWDAVVEEFDGYRQIWHKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGSQLESEHALVRWLAQHILEPDSNASSQQLRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITHFRVQDQAFYHDRHSYEAVLDLSHAEESIALAEAERLAED
                     LRLLYVALTRAVWHCSLGVAPLVRRRSDKKGETDVHQSALGRLLQKGEPMDAAGLRAC
                     IEALCDEDIVCRTPGNTDNDRWQIAAASHAELSARTLQRLLYDSWRVTSYSGLQQRGH
                     SVAQDLIPRLDIDAAGVGEAAEAPAMTPHHFPRGASPGTFLHSLFEELDFTQPIDPQW
                     VQEKLELSGFETRWEPVLTRWLDTVLHVPLNETGVSLSVLTEREKQVEMEFYLPIAQP
                     LTAGELDALIRRYDPLSAGCPALDFMQVRGMLKGFIDLVFRYEGRYYLLDYKSNWLGE
                     DSAAYTQTAMAAAMQAHRYDLQYQLYTLALHRYLRHRMANYDYERHFGGVIYLFLRGV
                     DSERPQQGIFTTRPAAALINQLDDMFAGEMSEEAQ"
     gene            11856..13691
                     /gene="recD"
                     /locus_tag="OPY25_001718"
     CDS             11856..13691
                     /gene="recD"
                     /locus_tag="OPY25_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HCS0927352.1"
                     /translation="MTIQKRLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSH
                     DAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPIDWKKRLLASAAVSCGDSPAPLIL
                     CGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGA
                     ALRQLPLTDAQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAGFTAERARQLSRLTG
                     SAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSD
                     IEKRTLQSSDDYAGMLDEALAGYGRYLRLLHEKAAPEAILQAFNEYQLLCALREGPFG
                     VRGLNDRIEQAMVQQRKIQRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGL
                     RVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPVVTRELV
                     YTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRIG"
     gene            complement(13794..15125)
                     /gene="argA"
                     /locus_tag="OPY25_001719"
     CDS             complement(13794..15125)
                     /gene="argA"
                     /locus_tag="OPY25_001719"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HCS0927353.1"
                     /translation="MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSS
                     IVSDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPIYHKNTRVTDAKTLELVKQAAG
                     LLQLDITARLSMSLNNTPLQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDA
                     INRQLDNGAIVLMGPVAVSVTGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSE
                     GGIISELFPNEAQARVEELEAQGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNMTIACAALYPFVEEKIGEMACVAVHPDYRSSSRGEVLLERVAAQARQM
                     GLRKLFVLTTRSIHWFQERGFTPVDIELLPESKKKMYNYQRRSKVLMADLG"
     gene            15358..16611
                     /gene="amiC"
                     /locus_tag="OPY25_001720"
     CDS             15358..16611
                     /gene="amiC"
                     /locus_tag="OPY25_001720"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HCS0927354.1"
                     /translation="MSGANSAISRRRLLQGAGAMWLLSVSQVGLAAVSQVVAVRIWPA
                     SSYTRVTVESNRLLKYKQFALSNPDRVVVDIEDVNLNSVLKGIGAQIRSDDPYIKSAR
                     VGQFDPKTVRMVFELKQNVKPQLFALAPVAGFKERLVIDLYPANAQDMQDPLLALLED
                     YNKGDLDKQVPPSQSGPQPGKAGRDRPIVIMLDPGHGGEDPGAIGKYKTREKDVVLQI
                     ARRLRALIEKEGNMKVYMTRNEDIFIPLKVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLKQLGKINDLHKNKVEQAGFAVLKAPDIPSILVETAFISNIEEERKLKTATFQ
                     QQVAESILAGIKAYFADGATLARRS"
     gene            complement(16721..16797)
                     /locus_tag="OPY25_001721"
     tRNA            complement(16721..16797)
                     /locus_tag="OPY25_001721"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16761..16763),aa:Met,seq:cat)
     gene            17005..18102
                     /gene="mltA"
                     /locus_tag="OPY25_001722"
     CDS             17005..18102
                     /gene="mltA"
                     /locus_tag="OPY25_001722"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HCS0927355.1"
                     /translation="MKGRWAKYVATGVMLAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQVDQIRSASPRLYTNQSNVYNAVQNWLRSGGDTRTMRQFGI
                     DAWQMEGTDNYGNVQFTGYYTPVVQARHTRQGAFQYPIYSMPPKRGRLPSRAQIYAGA
                     LSDKYILAWSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGWPYRSIGKVLIDR
                     GEVKKEDMSMQAIREWGEKHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLIGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFSGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PDAGHRAGWYNHYGRVWVLKSAPGAGNVFSG"
     gene            18211..19017
                     /gene="tcdA"
                     /locus_tag="OPY25_001723"
     CDS             18211..19017
                     /gene="tcdA"
                     /locus_tag="OPY25_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HCS0927356.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQRFAEAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVIDDFITPDNVAGYMDAGFTYVIDAIDSVRPKAALIAYCRRYKVPLVTTGGAGGQID
                     PTQIQVADLAKTIQDPLAAKLRERLKHNFGVVKNSKGKLGVDCVFSTEALVYPQADGS
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKIMAKAARQE"
     gene            complement(19069..19956)
                     /gene="rarD"
                     /locus_tag="OPY25_001724"
     CDS             complement(19069..19956)
                     /gene="rarD"
                     /locus_tag="OPY25_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461905.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HCS0927357.1"
                     /translation="MFVVLAFILWGLTPLYYQYLSGGNLAQILIYRVFWSIPLLLAVR
                     LLFRQRTRFHDAWKDKKSFFFCMIAGLLMIVSWSSFIYALTHHLVLDASLGYFINPLF
                     VIALGCIFLKEKLSLFQAIAVFSGVCGLTFQIIMLRHFPALALTMGLSFALYGLARKF
                     IHYDVMTSITIETLWALPVSLLIFLFSDTGPIISANTPFFLYVMTAPVTIIPLVLFAI
                     ALNHTSLIVTGLAQYIEPSLQFLLAIMIFGEHINYAELLCFCAVWFGLFLCISENLYS
                     HYLRARLKPVFGRVQRFFR"
     gene            complement(20256..20699)
                     /gene="csdE"
                     /locus_tag="OPY25_001725"
     CDS             complement(20256..20699)
                     /gene="csdE"
                     /locus_tag="OPY25_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HCS0927358.1"
                     /translation="MTNPLYTGHPFGTTVTEETLRAIFLPLTQWEDKYRQLILLGKQL
                     PALPDECKAQAKEIAGCENRVWLGFTRSDNGTMHFFGDSEGRIVRGLLAVLLTAVEGK
                     NAAELQARSPLALFDELGLRAQLSASRSQGLNALSEAIVAATHKG"
     gene            complement(20699..21904)
                     /gene="csdA"
                     /locus_tag="OPY25_001726"
     CDS             complement(20699..21904)
                     /gene="csdA"
                     /locus_tag="OPY25_001726"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HCS0927359.1"
                     /translation="MNAFNPTQFRAQFPALADAGVYLDSAATALKPQAVIDATHQFYC
                     LSAGNVHRSQFAQAQRLTAQYEAARAKAARLLNAPDEKSIVWTRGTTEAINMVAQCYA
                     RPRLRPGDEIIVSVAEHHANLVPWLMVAQQTGAQVIKLPLNDRRLPDVERLPELITSR
                     SRILALGQMSNVTGGCPDLTGAISAAHAAGMVVMIDGAQGAVHFPADVQQLDIDFYAF
                     SAHKLYGPTGIGVLYGKPELLEAMSPWLGGGKMIRDVSFEGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLSDIDIEQAENWSRGLATLAEDALAKRPGFRSFRCQDSSLLAFDFV
                     GVHHGDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTQHDVDALVNAV
                     DRALELLVD"
     gene            22097..22324
                     /locus_tag="OPY25_001727"
     CDS             22097..22324
                     /locus_tag="OPY25_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCS0927360.1"
                     /translation="MKKTAAIISACMLTFALSACSGPNYVMHTNDGRSIVTDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVALEN"
     gene            22671..23588
                     /gene="gcvA"
                     /locus_tag="OPY25_001728"
     CDS             22671..23588
                     /gene="gcvA"
                     /locus_tag="OPY25_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HCS0927361.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLPP
                     SFAIQWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQAYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGIALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAATEQEKFRFRYEQ"
     gene            23607..24002
                     /locus_tag="OPY25_001729"
     CDS             23607..24002
                     /locus_tag="OPY25_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HCS0927362.1"
                     /translation="MTSRFMLIVAAISGFIYVALGAFGAHVLSKTLGVVEMGWIQTGL
                     QYQAFHTLAIFGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAYIT
                     PVGGVSFLVGWALLLIGAIRMKRKGASHE"
     gene            23995..25095
                     /gene="rlmM"
                     /locus_tag="OPY25_001730"
     CDS             23995..25095
                     /gene="rlmM"
                     /locus_tag="OPY25_001730"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HCS0927363.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIY
                     ECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYT
                     GYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVC
                     DMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNA
                     QIQARQLYHDREEVTVHVRRLWAAVGGRRDER"
     gene            complement(25154..25864)
                     /gene="fucR"
                     /locus_tag="OPY25_001731"
     CDS             complement(25154..25864)
                     /gene="fucR"
                     /locus_tag="OPY25_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HCS0927364.1"
                     /translation="MKAARQQAIVDLLINHKSLTTEALATRLNVSKETIRRDLSELQT
                     QGKVLRNHGRAKYIHRENQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMTIALDAS
                     STCWYLARQLPDIPIQVFTNSHPICQELGKRERIALISSGGQLERKYGCYVNPSLISQ
                     LKSLDIDLFIFSCEGIDGGGDLWDSNAINADFKSILLRRASQSLLLIDKSKFNRSGEA
                     RIGHLDDVTHIVSDAPQS"
     gene            complement(25922..26344)
                     /gene="fucU"
                     /locus_tag="OPY25_001732"
     CDS             complement(25922..26344)
                     /gene="fucU"
                     /locus_tag="OPY25_001732"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HCS0927365.1"
                     /translation="MLKTISPLISPTLLKVLAEMGHGDEIIFSDAHFPAHSLGPQVIR
                     ADGLSVSDLLRAIIPLFELDSYAPPLVMMAAVEGDTLDPSVEARYRDALSLEAPCPDI
                     VRIDRYAFYERAQKAFAIVITGECAKYGNILLKKGVTP"
     gene            complement(26346..27764)
                     /gene="fucK"
                     /locus_tag="OPY25_001733"
     CDS             complement(26346..27764)
                     /gene="fucK"
                     /locus_tag="OPY25_001733"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HCS0927366.1"
                     /translation="MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENS
                     AWHQWSLDAILQRFADCCRSLSSALSECVVRGITVTTFGVDGALVDAQGKLLYPVISW
                     KCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
                     SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIG
                     TLQTDAARLLGLPAGVPVISAEHDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDT
                     SLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPETPWQTLIDEARAIPA
                     GAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNA
                     TELLLVGGGSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQAR
                     AQVNYQYRYFWPQTEPEIIEGV"
     gene            complement(27910..29640)
                     /gene="fucI"
                     /locus_tag="OPY25_001734"
     CDS             complement(27910..29640)
                     /gene="fucI"
                     /locus_tag="OPY25_001734"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HCS0927367.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALITEK
                     IRHACGAQVECVIADTCIAGMAESAACEEKFSSQNVGVTITVTPCWCYGSETIDMDPM
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSVGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDQNASQYKRNEAQNRAVLKESLLMAMCIRDMMQG
                     NKTLADKGLVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEALLNSSFDWNGVREPFVV
                     ATENDSLNGVAMLFGHQLTGTAQIFADVRTYWSPEAVERVTGQALSALAEHGIIHLIN
                     SGSAALDGACKQRDSEGKPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKAMHDQLDARTNSTWPTTWFAPRL
                     IGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLAAMLRIPVCMHNVEEAKIYRPSA
                     WAAHGMDIEG"
     gene            complement(29672..30988)
                     /gene="fucP"
                     /locus_tag="OPY25_001735"
     CDS             complement(29672..30988)
                     /gene="fucP"
                     /locus_tag="OPY25_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HCS0927368.1"
                     /translation="MGNTTIQTQSFRAVDAEQSKSKRYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFVIPIPAGILMKKLSYKAGIITGLFLYA
                     FGAALFWPAAEIMNYTLFLIGLFIIAAGLGCLETAANPFVTALGPESGGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQEALDKMTPDQLSAYKHSLVLSVQTPYMIIVAI
                     VLVVALLIMLTKFPALQSDDHSDAKQSSFLSSLSRLIRIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAIEEIPGMTPGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALL
                     AMLLCLISAFSGGHIGLLALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGKIPTAELVPALCFAVIFIFARFRSQAATN"
     gene            31544..32191
                     /gene="fucA"
                     /locus_tag="OPY25_001736"
     CDS             31544..32191
                     /gene="fucA"
                     /locus_tag="OPY25_001736"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HCS0927369.1"
                     /translation="MERNRLARQIIDTCLEMTRLGLNQGTAGNVSVRYQGGMLITPTG
                     IPYEKLTESHIVFIDADGQHEQGKLPSSEWRFHMAAYQTRPDANAVVHNHAVHCTAVS
                     ILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSDHVAVALKNRKATLLQHHGLIAC
                     EENLDKALWLAHEVEVLAQLYLSTLAIVDPVPVLDDEAIAIVLEKFKTYGLRIEE"
     gene            32208..33356
                     /gene="fucO"
                     /locus_tag="OPY25_001737"
     CDS             32208..33356
                     /gene="fucO"
                     /locus_tag="OPY25_001737"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HCS0927370.1"
                     /translation="MANRMILNETAWFGRGAVDALTDEVTRRGYHKALIVTDKTLVQC
                     GVVDKVTSRMDAAGLAWEIYAGVIPNPTISVVQEGLKVFTQSGADYLIAIGGGSPQDT
                     CKAVGIISNNPEFADVRSLEGLSPTRKPSVPIMAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQAAFIDADMMDGMPPALKAATGVDALTHAIEGYITRAAWALTDALHI
                     KAIEIIAGALRGAVAGEKEAGEAMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRFNAGSTNEKFRDIARAMGVKVEGLSLEEARNAAVEAVFTLNRDVG
                     IPLHLRDVGVRKEDIPALAQAAFDDVCTGGNPREASLADIVELYHTAW"
     gene            complement(33448..34203)
                     /gene="xni"
                     /locus_tag="OPY25_001738"
     CDS             complement(33448..34203)
                     /gene="xni"
                     /locus_tag="OPY25_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HCS0927371.1"
                     /translation="MAAHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIIHSQPTH
                     AVAVFDDDARSSGWRHQRLPDYKAGRPPMPDDLHNEMPALRAAFEQRGVRCWASDGNE
                     ADDLAATLALKVTEAGHQATIVSTDKGYCQLLSPGLRIRDYFQKRWLDAPFIEKEFGV
                     LPRQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVQFQNLEGIYAHLDEVPEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(34374..35741)
                     /gene="sdaB"
                     /locus_tag="OPY25_001739"
     CDS             complement(34374..35741)
                     /gene="sdaB"
                     /locus_tag="OPY25_001739"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461891.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HCS0927372.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARHILTDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDAIPSFIQDVNTHGRLLLANGQ
                     HEVEFPVDKCMNFHADNLSLHENGMRITALAGNKVLYSQTYYSIGGGFIVDEEHFGLT
                     NSEPVNVPYPYKTAADLQRHCQETGLSLSGLMMQNELALHSKEALEQHFAKVWEVMRS
                     GIERGITTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDKFIREVNANSLARYMLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVTCD"
     gene            complement(35800..37089)
                     /gene="sdaC"
                     /locus_tag="OPY25_001740"
     CDS             complement(35800..37089)
                     /gene="sdaC"
                     /locus_tag="OPY25_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HCS0927373.1"
                     /translation="MKTTQTSTIASIDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFLTHQLAINPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVAALMLLALYLIPQWNGAALETLSFDSAASTGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGEGAEKKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPIIAWMAPIIAMIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNKITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVIMGLIAISAIFYSLFS"
BASE COUNT         8756 a         9512 c        10480 g         8648 t
ORIGIN      
        1 ccctttgtct caatcttcgg cgcggattcc tgaaattttg caacgcgctg caagacatga
       61 acttttttcc gtaacgcgtc gaacaatctg tatttggcgc tcgttatttt tcttccgccc
      121 gccatactgc cgacatgaaa aaacaacagg gctatacgct cattgaaacg gtggtcgcga
      181 tgtcgctcat tatcattctc agcgccacag gactttatgg ctggcaacgc tggcagcagc
      241 aacagcgcct gtggcaaacc gcatgtcagg tgcgggatta cctgctgcaa cttcgtgagg
      301 acgctcactg gcataaccgc gatcacattc ttcgcgtggt cagcgaaggc ggttcatggt
      361 gctttgtcag ctctgttgct acgcaaacat cgtgtacgcc atcttccccc tttgtgttta
      421 cgcccgactg gcgtgatgtc gtccttgccg atatcacgcc gtcgttagcc ttctttggcc
      481 tgcgcaatac ggcatgggca gggcacatcg tgctgaaaaa cgctgccgga gagtggcgtc
      541 tggtcgtctc ctcctggggg cgaatcaggc tatgtgagcg taacgaggcc gccacgtgtc
      601 aataaccacg cgggggttct cgctactgga ggttgtgctg gcgatggcga taggttccat
      661 tttactgctt gggtccgcac gatttttacc ggcgttacag cgtgagatct ggcacaacac
      721 gcgacagtta tcgctggaag atgaaatctg gcagcgaacc tataccgtag cgaagcatct
      781 tcaacgtgcg ggttactgtc atggccactg tatcggcgaa gggctacatc ttgccgaaca
      841 ggggcaatgc gtcatcgttc agtgggacgg gaataataac ggggtctggg ataccatacc
      901 ggcgaaagag gccgaccaga ccgggttccg tatgaaggat aacgttctgg agacattacg
      961 cggagcaaca tcttgccagg gtaagggatg ggaaaaaatg accgatccca atacggtact
     1021 catcacggcg tttaacgttg agcgccggga tataacggga ttctcgccag tgctcatgct
     1081 gcatctgcgt ggcgccagca aagccgagcc tcagacggtt attgacgcgc aatatagcgt
     1141 aacgggattt aatctgtgaa tcgggaacgt ggcgcttctt cgctaatact ggcgctttta
     1201 atactgattc tgggcagtct gctactgcaa ggcgtaaatc agcagcaggc cagctatgcc
     1261 gcccgcgtga cgacgcagag catggcgata caacgccagg cgctcgtaca gtcggcgctg
     1321 gaatgggggc gagggcagct atggtcaggc gtaaccgaaa tggaatgtcg gcgctattcc
     1381 tcttcaggag cgagggtctg tttgcggaga ttatcggggg atgaagtggt gatggcggcg
     1441 caagatgatg gcatgacgtt atggcgtttg ggcaacgtca ttcagggaag cattgtcttt
     1501 tctccccacg gctggagtga tttttgtccg ttaaaagagg tggcgttatg tcgcatcccc
     1561 tgaattttca acgcgggttt agcctcccgg aagttttagt ggcgatggtt ctaatggtaa
     1621 tgatcgtcac cgcgctgtca ggctatcagc gggtattaat gcacactttt gcattacgac
     1681 accagtatct ccagatctgg cggcaggcgt ggcagcaaac ggcgctgtat ccattttcgc
     1741 ctgctgacgg ctggaatgcc aaccggatgc agacaacgca atcgggatgt gtcagcatca
     1801 gcgtcacgat ggtttcaccc tctggcaggc aggggcagat gacgcgcttg cattgtccaa
     1861 atcgttaatc gtcaggagta attatgttaa gggtctacca ctccaatcgt ctggatgtgc
     1921 tggaagcgtt gatggagttc atcgtcgaac gcgagcggct ggatgatccc tttgaaccag
     1981 aaatgattct ggtacaaagc acgggtatgg cgcagtggct gcagatgacc ctttcacaaa
     2041 agtttggtat tgcggcgaat atcgcttttc cgttaccggc gagttttatc tgggagatgt
     2101 ttgtccgcgt gttgccagat atccccaaag aaagcgcttt cagcaaacaa agcatgagct
     2161 ggaaactgat gaccttgctg ccgcagttgc tggataagga tgagtttgta ctgctgcgcc
     2221 attatctgac cgacgacacc gataaacgca aactctttca gctttccgcg cgcgccgccg
     2281 acctgttcga tcagtatctg gtttatcggc ctgactggct tacgcagtgg gaggcgggaa
     2341 aaaccgtgga aggtctggga gaggcgcaaa actggcaggc gccgctgtgg aaagcattgg
     2401 tggaatatac cgccgcgctg gggcagccgc gctggcatcg cgccaatctc taccaacgct
     2461 ttattcaaac gctggaaagc gcgaccgcct gcccgccagg gttgccgtcc cgcgttttta
     2521 tttgcggcat ttccgcgtta ccgccagtgt atctcaaagc attgcaggcg ctgggtaaac
     2581 atattgaaat ccatctcctt tttactaatc cgtgtcggta ttactggggg gatataaaag
     2641 acccagcctg gctggcaaaa ctcatggctc gccagcgtcg tcacagtttt gaagaccgtc
     2701 atttaccgtt gttccgtgaa aatcagaatc cggaagcctt atttaacagc gacggtgaac
     2761 aggatatcgg taatccgcta ctggcctcat ggggaaaact gggacgggat tatatctacc
     2821 tgctatctga actggaaaac agccaggagc tggatgcgtt tgttgatatt acgccagata
     2881 atcttttgca tcggattcag gcggatatcc ttgaactgga aagccatgcg gtggcgggcg
     2941 taaatcttga ggagtattcg cgcagcgaca ataagcgtct gctcgatccc gaggataaca
     3001 gcctctcttt tcacgtttgt cacagcccgc agcgcgaggt ggaaatactg cacgatcgcc
     3061 tgctggcgat gctggaagcc gatccgacgc taacgccgcg cgacattatc gttatggtgg
     3121 ctgatattga cagctatagc ccgtttatcc aggcggtatt tggtagcgcg ccaacggagc
     3181 gctatctgcc ttatgctatt tccgatcggc gggcgcgtca gtcacatccg gtgttacagg
     3241 catttatcag tctgctttcg ttaccggaca gccgcttcgt ctccgaggat gttctggcgt
     3301 tgttagacgt accggtattg gctgcccgct ttacgatcaa cgaagaaggg ctgcgttatt
     3361 tgcgcttgtg ggtcaatgag tcaggcattc gctgggggat tgacgatgac aacgtgcgcg
     3421 agctggaact tcctgccacg gggcagcata catggcaatt tggcctgacg cgtatgctgc
     3481 tggggtatgc gatggaaagc gcccagggcg agtggcagtc ggttctgcct tatgacgaat
     3541 ccagcggtct gattgctgag ctggtcgggc atctggcttc gctgctgatg cagcttaata
     3601 tctggcggcg cggtctggcg caggagcgac ctctggaaga gtggttgccc gtttgtcgcg
     3661 acatgctcaa tgatttcttc ctgcccgatg cggacacgga agcggcaatg acattgattg
     3721 aacagcagtg gcaggccatt atcgccgaag gcgtcgcggc ggaatatggc gacgcggtac
     3781 cgatttcgct actgcgggat gagctggcgc agcgtctgga tcaggaacgt attagccagc
     3841 gcttcctggc gggccccatc aatatttgta cgctgatgcc gatgcgttcc attccgttca
     3901 gagtcgtttg cctgctggga atgaacgacg gcgtataccc gcgccagctt gcgccgttgg
     3961 gctttgacct gatgagccaa aaacccatgc gcggggatcg tagccgtcgc gacgatgacc
     4021 gctacctgtt tctggaagcg ttaatctcgg cgcagcagac gctgtatatc agctacatcg
     4081 gtcgctccat ccaggataat agcgaacgct ttccctctgt actggtgcaa gaattggtgg
     4141 attacatcgg gcaaagccac tatttgccgg gcgacgaaac gctgacctgt gatgagagcg
     4201 aagcacgagt caaagcgcat attacgcgtc tgcatacccg tatgcctttt gatgcgcaaa
     4261 attaccaacc cggcgaacag caaagttatg ccagagagtg gttgcccgcg gcgagtcagt
     4321 cgggaaaagc gcattctgac tttgtgcagc cgcttccttt tacgatgccg gaaacattga
     4381 ctctggaaag tctgcagcgt ttttgggccc atccggtacg cgcatttttt cagatgcggc
     4441 ttcaggttaa tttccgctcg gaagagagtg agattcctga tgctgaaccg tttgaattag
     4501 agggattgac gcgatatcaa cttaaccaac agttgctcaa tacgttggtt gaagaggacg
     4561 atgccgaacg cttgttccgc cgttttcggg ctgcgggaga gctgccttac ggcgcgtttg
     4621 gcgaaatatt ctgggatgcg cagtgtcagg agatgcagca actggcaagc cgggttatcg
     4681 cttgccgtaa gccgagccaa agcctggaag tggatctgct ttgcaatgga gttcagctaa
     4741 ccggctggct accgcaggta caggaggatg gattattgcg ctggcgtccc gctttaatca
     4801 gcgtggcgca aggtgtgcaa ctttggctgg aacaccttgt ctattgtgcc agcggcggta
     4861 gtggcgaaag tcgcctgttt ttgcgcaaag agggagaatg gcgatttccg cctcttgata
     4921 aaacgcaggc aatggcttac ctggcgcaac tgattgaagg ctaccgggaa ggcatgtctt
     4981 ctccgctatt ggtactgccg gaaagcggcg gcgcatggat aaaagcctgt tatgacgctg
     5041 aaaatgatgt catgttagac gacgatgata ctttacagaa ggccaggaca aagtttctac
     5101 aggcttatga aggcaacatg atggtgagcg gcgaaggcga agatatctgg tatcaacgtc
     5161 tttggcgtca gctggaatcg gaaacgttgc aggctatcat tgcgcagtca cggcattacc
     5221 tgttaccgct gtttcgtttt aatcagtctc gttgattgta tgaaaatcgc gccattaaaa
     5281 ggcttcgact atgatgcgct cttcgtcacg gactgattac tgataaaaaa atgctgcctg
     5341 gttcagcaca ataatatccc gttccgctca ggtcgatggt ttacgtgacc atacagatga
     5401 gtgggaatga aagttaatga tgaggtccgt gaatgccccg cagcacctgg ttcaaagcgt
     5461 tattgttatt ggtcgccctc tgggggcctg cagttcaggc ggatatcggt tggcaaccgc
     5521 tgcaagaaac tatccgtaaa agcgataaag atacccggca gtatcaggcg atacgtcttg
     5581 ataatgacat ggtggtgttg ctggtatccg atccgcaggc tgtaaagtct ctttctgcgt
     5641 tagtggtgcc cgttgtatcg cttgaagatc ctgaggctca tcaggggctt gctcattatc
     5701 ttgagcatat gtgcctgatg gggtcaaaaa aatatccgca ggcggatagc cttgccgaat
     5761 accttaaaag acatggcggt agccacaacg ccagcaccgc accttatcga acagccttct
     5821 acctggaggt tgaaaacgac gcgcttccag gtgccgtaga tcgcttggcc gacgccattg
     5881 ccgcgccatt gctcaataaa aagtatgccg aacgcgaacg aaacgcagtg aatgccgagc
     5941 tgacgatggc gcgcacccgt gacggtatgc gtatggcgca ggtaagcgcc gaaaccatta
     6001 acccggcgca tccaggctcg cacttttcag gcggcaatct ggaaacgcta agcgataagc
     6061 cgggcaatcc ggtgcaacag gcgttgatcg cttttcatga aaaatactat tcatctaatc
     6121 tgatgaaggc ggtgatttac agtaataaac ccttgccgga actggcgagt attgccgccg
     6181 caacctatgg tcgcgtgccg aataaacaga ttaaaaaacc ggaaattacc gtacctgtca
     6241 tcaccgaggc gcagaagggc atcattattc attacgtgcc ggcgctaccg cgtaaagtgc
     6301 tgcgcgtgga gtttcgtatt gataacaata gcgcgcagtt ccgtagcaag accgatgaac
     6361 tggtctctta tctgattggc aatcgtagcc cggggacgct ctctgactgg ctgcaaaaac
     6421 aaggactggt cgaaggtatt agcgcggatt ctgatccgat tgttaatggt aacagcggcg
     6481 tatttgccat ttcggcaacg ctgactgata aaggtttggc caatcgtgat gaagtcgtcg
     6541 cagctatctt tagctatctc aatacgttac gtgaaaaagg gatagataaa cgttactttg
     6601 acgagctggc gcatgtgctg gatctcgact tccgctatcc gtcgattacc cgcgatatgg
     6661 actatgtcga gtggctggcg gacactatga tccgcgtccc ggtagcgcat acgctggatg
     6721 cggcgaatat cgccgatcgt tacgatcctg ccgctatcaa aaatcgcctg gcgatgatga
     6781 cgccgcagaa tgcgcgcatc tggtacatca gtccccagga accccataat aagattgcgt
     6841 attttgtgga tgcgccttat caggtcgata agattagcga acagacgttt aaaaactggc
     6901 agcaaaaagc acagggcatt gcgttgtcgc tgccggagtt aaacccctat attcctgatg
     6961 attttacgct tattaagaat gacaaaaact acgtgcggcc agaactgatt gtcgataaag
     7021 cggatttgcg cgtggtttat gcgccgagtc gttatttcgc cagcgagcca aaagctgacg
     7081 tgagtgtggt attgcgtaac ccgcaggcga tggacagcgc ccgcaatcag gtactgttcg
     7141 cccttaatga ttatctggcg ggaatggcgc tagatcagct cagcaaccag gcggcagtgg
     7201 gcggcattag cttttccact aacgccaaca atggtctgat ggtcactgcg aacggttata
     7261 cccagcgttt gccgcagctt ttcctggcgc tgctggaagg atattttagc tacgacgcca
     7321 cggaagaaca gctggcgcag gcgaaatcct ggtatacgca gatgatggat tctgcggaga
     7381 agggaaaagc ctacgaacag gcgattatgc cggtgcagat gatttcgcag gtgccttatt
     7441 tttcccgtga tgaacgtcgc gctttgctgc cgtccattac gttaaaagag gtgatggcct
     7501 atcgtaatgc gttaaaaacg ggcgctcgtc cggaatttct ggttatagga aatatgagcg
     7561 aagcccaggc gacctctctg gcgcaagatg tccaaaaaca gctcgcggcg aacggatcgg
     7621 cgtggtgtcg taacaaagac gtggtggttg agaaaaagca gtccgtaata tttgaaaaag
     7681 cgggcagtag caccgactcc gcgttagccg cggtctttgt cccggtcggc tacgacgagt
     7741 acgtcagcgc cgcctacagc gcgatgttag gtcagattgt tcaaccgtgg ttttacaatc
     7801 agctacgaac cgaagagcaa ctgggatacg ctgttttcgc ctttccgatg agcgttggcc
     7861 gtcagtgggg aatgggattc ctgctacaga gcaacgataa acagccctct tacctgtggc
     7921 aacgctatca ggcatttttc cctgacgccg aggcgaagct gagggcgatg aagccggaag
     7981 agttcgccca aattcagcag gcgatcatta cgcaaatgcg ccaggcgccg caaacgttgg
     8041 gcgaagaagc atcccgttta agcaaggatt tcgatcgggg taatatgcgc tttgactcgc
     8101 gtgataaaat catcgctcag ataaaattgc tgacgccaca aaagcttgcc gatttcttcc
     8161 accaggcggt ggtggaacca caaggtatgg caatattgtc acagattgcc ggtagccaga
     8221 atggaaaagc agaatacgtg catccgacag gctggaaagt gtgggataac gtcagcgctt
     8281 tgcagcaaac gttacctcta atgagcgaaa agaatgaatg atgtcgccga gactcttgat
     8341 cctctgcgct tgccccttac aggcgagcgt ttgattgaag catcagcggg cacaggcaaa
     8401 acgtttacta tcgcggcgct gtatctgcgg ctactgctcg gtttaggcgg cagcgccgca
     8461 tttccccgtc cgttgaccgt tgaagaactg ctggtggtaa cctttacgga ggccgccact
     8521 gaagagctgc gtgggcgaat ccgcagtaat atccatgagt tgcgcatcgc ctgtctgcgg
     8581 gaaagcacgg ataatccgct gtatgcccgc ttgctggaag aaattagcga caaaaagcag
     8641 gccgcgcagt ggttattact ggcagaacga caaatggacg aggccgcggt ttttaccatc
     8701 cacggttttt gccagcgtat gctcagcctg aacgctttcg aatccggtat gttgtttgag
     8761 caacagctta ttgaagacga atctttgttg cgttatcagg cctgcgccga tttctggcgg
     8821 cgtcattgct atccgctgcc gcgcgacatc gcgcaggtgg tgtttgacgt gtggaagggg
     8881 ccgaaggcgc tcttaaaaga tatcgatcgt tatctgcagg gcgaagcgcc ggtcattaaa
     8941 gcgccgccat cgcaggagga gacgctggca tcgcgccatg aacagatcct ggcgcgcatc
     9001 aaccaggtga agcagcagtg gtgtgaggcg gttagcgagc tggacgcgct gatcgaatca
     9061 tccggcatcg atcgcagaaa attcaaccgc ggcaatcagg cgaaatggat cgaaaagatc
     9121 accgcgtggg cgcaagaaga gaccaaaaat tatcaattac ccgaggcgtt gggaaaattt
     9181 tcacagcgtt ttttagctga gcgcaccaaa gctgggggcg tgacgcccca gcacccattg
     9241 tttgtcgcca ttgataacct gttgggcgaa ccgctatcga ttaaagatct ggttcttacc
     9301 cgagcgctct cagagatccg tgaaacggtg gctcaggaaa aacgacggcg cggcgagctg
     9361 gggtttgacg atatgctcag ccgtttagat accgcgctgc gtagtgaaag cggcgaggcg
     9421 ctggctgcgg cgattcgtac ccgttttccg gtggcgatga tcgatgaatt tcaggatacc
     9481 gacccacaac agtaccgtat ttttcgccgt atctggcgac atcaacccga tacggcgcta
     9541 ttgctgattg gcgatcctaa acaggcgatt tatgcgtttc gtggcgcgga tatctttacc
     9601 tacatgaagg ctcgcagcga agtgagcgcg cactataccc ttgacactaa ctggcgctcc
     9661 gcgccgggga tggtgaatag cgttaacaag ctgttcagtc agatgaatga cgcctttatg
     9721 ttccgcgata ttcccttcag tccggtaaag tttgcgccca gaaaccagtc gctgcaattt
     9781 aaagtgaatg acgcgcctca accggcgatg accctgtggc taatggaggg ggaaagctgc
     9841 ggttcgggcg attatcaaag ttatatggcg caggtgtgcg ccacgcaaat tcgcgactgg
     9901 ctgcgtgccg ggcaaacggg cgacgcgctg ctgacgaacg gcgattcgtc gcggcccgtt
     9961 cgcgcctcgg atattagcgt gctggtgcgc agcaggcggg aagccgcgct gatacgggat
    10021 gcgctgacct tactggcgat cccctccgtc tatctttcta accgcgacag cgtattcgaa
    10081 acgctcgaag cgcaggaaat gctgtgggtg ttgcaggcgg tgatggcgcc cgaacgtgag
    10141 aatacgctgc gtagcgctct ggcgacatca atgatgggcc ttaccgcgct ggatatcgaa
    10201 acgcttaaca atgatgaaaa tgcgtgggat gcggttgttg aagagtttga tggctaccga
    10261 cagatttggc ataaacgcgg cgtgatgcct atgctgcgcg cgctaatgtc ggcgcgcaat
    10321 attgctgaaa acctgctggc gacggcggga ggtgaacgtc ggctgacgga tattctgcat
    10381 attagcgaac tgttacagga agccggttcg cagctggaaa gcgaacatgc gctggtgcgt
    10441 tggctggcgc aacatatcct tgaacctgat agcaatgctt ccagccagca actacgtctg
    10501 gaaagcgata agcatctggt gcaaatcgtc accattcata aatcgaaagg tctggaatac
    10561 ccgctggtct ggttaccttt tatcacccat ttccgcgtgc aggaccaggc tttttatcac
    10621 gacaggcact cctacgaggc ggtgctggac cttagtcacg ccgaagagag catagcactg
    10681 gcggaagccg aacgcctggc ggaagacctg cgcctacttt atgtcgcgct gacccgtgca
    10741 gtgtggcatt gcagcctcgg cgtcgcgccg ctggtgcggc gtcgtagcga taagaaaggc
    10801 gagacggatg tgcaccaaag cgcgcttggg cgactcctgc aaaaaggcga accgatggat
    10861 gccgcaggcc ttcgcgcctg tattgaggcg ctatgcgacg aggatatcgt gtgtcgaacg
    10921 ccaggcaata cggataacga ccgctggcaa attgccgctg catcgcacgc ggaactcagc
    10981 gccagaacgc tgcaacgcct gctttatgat agctggcgcg tcaccagtta ttccggtttg
    11041 cagcagcggg gacatagcgt ggcgcaagat cttattcctc gtctcgacat tgacgccgca
    11101 ggcgttggcg aagcggcgga agcgccggca atgacgccgc atcactttcc tcgcggggca
    11161 tcgccgggaa catttttgca cagcctgttt gaagagcttg attttactca accgatagac
    11221 ccccaatggg tacaggaaaa actggagctg agtggttttg aaacgcgatg ggagcccgta
    11281 cttacccgct ggctggacac cgtgttgcac gttcccctta acgagacggg cgttagtctg
    11341 agcgtgctga ccgagcgtga aaaacaggtt gaaatggagt tttatctgcc gattgcccag
    11401 ccgcttaccg ccggagagtt agatgcgttg attcgtcgat acgacccgct ttcagcaggt
    11461 tgccctgcgc tggatttcat gcaggttcgc ggcatgttaa agggctttat cgacctggtg
    11521 ttccgttatg aggggcgcta ttacctgctc gactataaat ctaactggct gggcgaggat
    11581 agcgccgctt atacccagac ggcgatggct gcggcgatgc aggcgcatcg ctatgatttg
    11641 cagtaccagc tttatacgct ggcattgcat cgttaccttc gtcatcgaat ggcgaattac
    11701 gactatgaac gccatttcgg cggcgtcatc tatctctttt tacgcggggt ggatagcgaa
    11761 cgtccgcagc agggtatttt taccactcgt cctgcggcgg cgttaattaa ccaactggat
    11821 gatatgtttg caggtgaaat gagtgaggag gcgcaatgac aatccagaag cggttgctgg
    11881 aggccgttga acaaaaactc ttacggccca ttgatgccca gtttgcttta accgtcgccg
    11941 gtaacgacga tcccgccgtg acgctggcgg cagcgctgct tagtcatgac gcaggtgaag
    12001 gtcacgtgtg tctgccgttg tcgcgtttaa cgttaacgga ggaggcgcat cccttactgg
    12061 tcgcctggat aagcgaaacg gctacgccaa tcgactggaa aaagcggtta ctggcgtctg
    12121 cggcggttag ctgcggcgat agccccgcgc cgttaattct gtgcggcgat cgcctctacc
    12181 tgaatcgcat gtggtgcaac gagcgtacgg ttgcgcgctt ttttaacgag gttaaccagg
    12241 ccatcgccgt agatgaagat cagttatccc gtattctgga cgcgctattc cctccgacag
    12301 acgaggtgaa ctggcaaaag gtggccgccg ccgtagcgct aactcgccgt atctccgtga
    12361 tttcaggcgg tcccggcacc ggtaaaacca ccaccgtcgc gaagctgctg gcggcattaa
    12421 ttcaaatggc ggatggcgaa cgttgccgta tccggctggc ggcgccaacc gggaaagcgg
    12481 ccgcacgcct gacggagtcg ctcggcgcgg cgttgcgtca gcttcctctt accgatgcgc
    12541 agaaaaagcg tataccggag gacgccagta cgctgcaccg actgctgggc gcacagcccg
    12601 gcagccagcg attacgccat catgcgggca acccgctgca tctggacgtg ctggtggtcg
    12661 atgaggcatc aatgattgat ttgccgatga tgtcacgttt gattgacgct ctgccgccgc
    12721 acgggcgggt catttttctt ggcgatcgcg atcagttggc atccgttgag gcgggcgctg
    12781 tgttgggcga tatttgcgcc tatgtcaacg cagggtttac ggcggaacgc gcccgacagc
    12841 taagtcgact cactggtagc gccattccgg cgggggccgg aacgcaagcc gcgtctttac
    12901 gcgatagcct ctgtttgttg caaaagagct accgtttcgg cagcgattct ggcatcggca
    12961 agctggcggc ggcaattaac tgtggcgaca ggtcggcaat ccaggctgtt tttcagcagg
    13021 ggtttagcga tatagagaag cgtacattgc aaagcagcga cgattatgcc gggatgctgg
    13081 atgaagcgct ggcgggctat gggcgctacc tgcggttgct gcatgaaaaa gcggcgccgg
    13141 aggcaatcct tcaggctttc aatgagtatc aactgctttg tgcgctgcgc gaaggcccat
    13201 ttggcgtgag gggactgaat gaccgcattg agcaggcgat ggtgcagcaa cgaaaaattc
    13261 agcggcatcc gcactctcgc tggtatgaag ggcgtccggt aatgattgcg cgcaacgata
    13321 gcgcgttggg gctatttaac ggcgatattg gtattgcgct cgatcgcggg caggggttac
    13381 gcgtctggtt tgtgatgccg gacggcacga tcaagtccgt tcagcccagc cgtctgccgg
    13441 aacatgatac aacctgggcg atgacggtac ataaatcaca ggggtctgaa tttgatcacg
    13501 ccgcgctgat tttacccagc caacgttcgc cggtcgtgac gcgggagctg gtgtataccg
    13561 ctgttacgcg ggcgcggcgg cggttatcgc tgtatgccga tgaacggatc ctggcaggcg
    13621 cgattgtgac gcgaacggaa cggcgcagcg ggttagccac cttatttgat gaagtcagtc
    13681 gtatcggata agacgagttc tcgccggatg gcgacgcgta gcgtcttatc cggcctccaa
    13741 atgatgcttt cgagcgtagg cctgataagc gcagcgccat caggcccccc ttgttatcct
    13801 aaatctgcca tcagcacctt tgaacgtcgc tgatagttat acattttttt cttgctctca
    13861 ggcagtaact caatatcgac aggcgtaaaa ccgcgctcct ggaaccagtg aatactgcgc
    13921 gtcgtcaaca caaacaattt acgcagcccc atttgccgtg cctgggcggc aacccgctcc
    13981 agaagcactt ctccacgcga tgagctgcga taatccggat gtaccgctac gcaggccatt
    14041 tcgcctattt tctcttccac aaaaggatac agcgccgcgc aagcgatagt catattatcg
    14101 cgctgaataa tggtaaattt atcgatctcc atctccagtt gttcacggga acggcgtacc
    14161 agaatgccct gctgttccag tgggcggata agctccagaa taccgccaat atcgttgatg
    14221 gtagcgcggc ggatctgctc ggcgctctcc atgacgatct gcgtaccgat accatcacgc
    14281 gagaacaatt cctgtaatag cgagccatct tcctgatagc tgatcagatg gcaacgacga
    14341 acgccgctac gacaggcttt taccgcgccg cgcaaaaaac gtacggttcc ggagttgtaa
    14401 tcgccctgcg cttccaactc ttccacccgc gcctgcgctt cattcgggaa gagttcagaa
    14461 atgatgccgc cctcgctatt ggtaacgccc tgagaagaac agaaaccgat cattttttcc
    14521 gctttcagtt taacggcgag ttgagtggca atctcttctg aggtcagatt aaaactttcg
    14581 ccggtcactg agacggcgac cggccccatc agaacgatcg cgccgttatc caactggcgg
    14641 ttgatcgcat cttcatcaat gcgccggata cggccgctat gacagtagtc cacgccatca
    14701 tcaacgccca gcggctgcgc aatggtgaaa ttgccgctga cgacattaat gtgcgcgccc
    14761 tgcaacggcg tattgttcag actcatcgac agacgggcgg taatatcaag ctggagtaaa
    14821 ccggcggcct gtttcaccag ctccagtgtt ttggcgtccg tcacccgtgt gtttttgtgg
    14881 taaatcggtt catgatgatg cgcggccaga ttggcgtcga tttgcggtcg cgcgccatac
    14941 accacgacaa ggcgaatacc gaggctatgc agtagcccga tatcgctaac gatgctggaa
    15001 aaattgtcat gctcaatggc ttcgccgccg agcataatga caaaggtttt tccgcgatgg
    15061 gtattgatat agggaactga atggcgaaac ccttctacca gttcggtttt acgttccttt
    15121 atcattgcgc gccccactag tgaattatta ttcgaaatta gtgtattttt attctgtttt
    15181 tgccctctgt gcaagcgtaa attttatgcg gtccgatcgc ttttcttagt aatgccgtga
    15241 atataaaaag aatgtttacc cttttataga tgacagatta tgcgtcattc gctaaagttt
    15301 ccggtcaatt tggatgaact ttgtatgatc tctatttagt ttttgctcgg gagaagcatg
    15361 tcgggagcca attcagcaat cagccgtcgc cgtttactac aaggcgcggg cgccatgtgg
    15421 ctattaagcg tgagccaggt cgggctggct gccgtaagcc aggtcgttgc ggtgcgtatc
    15481 tggcctgcgt ccagctatac ccgcgtcacg gtagagtcga atcgtctgct gaaatataaa
    15541 caatttgcct taagtaaccc ggaccgcgtg gtggtagata ttgaggatgt gaatctgaac
    15601 tcggtgctta aaggcattgg cgcgcagatt cgcagcgacg atccgtatat caaatccgca
    15661 agggtagggc agtttgatcc taagactgtg cgtatggtct ttgagctaaa acaaaacgtg
    15721 aagccgcagc tatttgcgct ggcgcctgtg gcaggcttta aagaacgtct ggtgatagat
    15781 ctttatcctg ctaatgcgca ggatatgcag gatccgctgc tggcgctgct ggaagactac
    15841 aataaaggcg atctggataa acaggtgccg ccttcgcaaa gcgggccgca gcccggtaaa
    15901 gcggggcgcg atcgtcccat tgtcattatg cttgatccgg gacacggcgg cgaagaccct
    15961 ggcgcgatag gcaaatacaa aacgcgtgaa aaagacgtgg tgctccagat agcccgccgc
    16021 ctgcgcgcgt tgatcgaaaa agaaggcaac atgaaggtct atatgacgcg caatgaagac
    16081 atcttcattc cgttaaaagt ccgggtggcg aaagcgcaga aacagcgcgc cgacctgttt
    16141 gtctctattc atgcggatgc cttcaccagc cggcagccta gcggttcatc cgtattcgcg
    16201 ctatcgacta aaggcgccac cagtactgcg gcgaaatatc tggcgcaaac gcagaacgcc
    16261 tcggacttaa ttggcggcgt gagcaaaagc ggtgaccgtt atgtcgacca tacgatgttc
    16321 gatatggtgc aatcgctgac cattgccgat agtttgaaat tcggtaaagc ggtgttgaag
    16381 cagcttggta aaattaatga cctgcataaa aacaaggtcg agcaggcggg gtttgcggtg
    16441 ttaaaggcgc ccgatattcc gtctattctg gtcgagacgg cgtttatcag taacattgaa
    16501 gaagaacgca agctcaagac cgcgacgttc cagcaacagg tcgcagagtc gattctggcg
    16561 ggcattaaag cctattttgc cgatggggcg acgctggcga gaagaagtta acctgagatg
    16621 acggcgagtt tattgcgcgg gtaagtagga tgctgcccgc actgtcgttg cggaccagat
    16681 gacagataca aaaaaacacc cgtaagggtg ttcattaagt tggttgcggg ggccggattt
    16741 gaaccgacga ccttcgggtt atgagcccga cgagctacca ggctgctcca ccccgcgtcc
    16801 gtggatgcgc actatactcc gctgagcttt tgttgcaacc cttttttcat ataaatcgct
    16861 aatttctcat gaattgcgca aatacaccgc agatagcgcg atttttaaac gaatttacat
    16921 aatgagatcg cgatcgcatt tcattacttc ggacggtttg ttatcttcac cgggcacttt
    16981 cgattacgca gaagacgaga caccatgaaa ggacgttggg caaaatatgt ggcgacaggc
    17041 gtaatgctgg caatgctggc tgcctgttca tcaaaaccga ccgatcgcgg tcagcaatat
    17101 aaggacggga aatttaccca gcccttctcc ctggtaaacc agccggacgc ggtgggcgcg
    17161 ccgattaatg ctggtgactt tgccgagcag gtcgaccaga tccgttccgc gtcgccgcgt
    17221 ttatacacca atcaaagcaa cgtctataac gctgtccaga actggttacg ttccggaggc
    17281 gatacgcgca ctatgcgtca gtttggtatc gatgcctggc agatggaagg caccgacaac
    17341 tacggtaacg tccagttcac gggctactat acgcccgtcg ttcaggctcg ccatacgcgc
    17401 cagggcgcgt tccagtaccc tatctatagt atgccgccaa aacgcggacg cttaccgtcc
    17461 cgcgcccaga tctacgcagg cgcgctgagc gataagtaca tcctggcctg gagtaattcg
    17521 ctgatggata actttattat ggatgtccag ggcagcggtt atattgattt cggtgatggt
    17581 agtccgctga acttctttag ttatgccggt aaaaatggct ggccttatcg cagtattggt
    17641 aaagtgctta tcgatcgcgg tgaagtgaaa aaagaagata tgtcgatgca ggctatacgc
    17701 gaatggggag agaagcacag cgaagcggaa gtgcgtgaat tactggagca gaacccgtcg
    17761 ttcgtcttct ttaaaccgca atcttttgcg ccggtcaaag gcgccagcgc tgtaccgctg
    17821 attgggcgag catccgtcgc ctccgaccgc agcatcattc cgccgggcac aaccttgttg
    17881 gcggaagtac cgttgctgga taacaacggt aaatttagcg gtcagtatga gctacgtttg
    17941 atggtcgcac tggatgtcgg cggagcgatt aaaggccagc actttgatat ttaccagggg
    18001 attggcccgg atgccgggca tcgtgccgga tggtataatc actatggtcg cgtctgggtg
    18061 ttaaaaagcg cgccgggcgc cggtaacgtg tttagcggct gattgtggta ttctgcgaca
    18121 accggattgc ccgataacgc gattgctatc gggcctgaaa atagtgagca ggggtgagga
    18181 ataacctcac cttttttatt ctgaggtcat atgtcagtgg tgataagtga tgcctggcgc
    18241 caacgctttg gcggcaccgc gcgtctgtac ggtgaaaaag cgctgcagcg gtttgctgag
    18301 gcgcatatct gcgtcgtggg aatcggcggg gtaggatcat gggcggcaga ggcgctggcg
    18361 cgtacgggca tcggcgcgat tacgctgatt gatatggacg atgtctgcgt gaccaatacg
    18421 aaccgtcaga tccatgcgtt gcgtgataac gttgggttgg cgaaagcgga agtgatggcc
    18481 gaacggattc ggcaaattaa cccggagtgc cgggtaacgg ttatcgatga tttcatcacg
    18541 ccggataatg tggcgggtta tatggacgcg ggttttacct atgtcattga cgccattgac
    18601 agcgttcgtc caaaagccgc gctgattgcg tactgtcgcc gatataaggt tcctttagta
    18661 accactggcg gcgcgggcgg gcagatcgat ccgacgcaaa tccaggtcgc tgatttggcg
    18721 aaaactatcc aggatccgct ggcggcaaaa ctgcgtgaga gattgaaaca taattttggc
    18781 gtagtgaaga acagtaaagg taagctgggc gtggactgcg ttttttccac cgaagcgctg
    18841 gtttacccac aggcggacgg ttccgtatgc gcgatgaaag ctaccgcaga agggccaaaa
    18901 cggatggatt gcgcctctgg cttcggcgcg gcgacgatgg taacggcaac gttcggtttt
    18961 gtcgccgttt cccatgcgct gaagaagatc atggctaaag cggcgcgaca agaataaaag
    19021 gacggggcgg agtgtcacgc agacgcgtat ccggccctgc gccctttgtt agcgaaagaa
    19081 gcgctgtacc ctgccgaaca ccggtttcag acgggcgcgg agataatggg aatataaatt
    19141 ttcagatatg catagaaaca gcccgaacca tactgcacaa aagcagagca gttccgcgta
    19201 attaatgtgc tcgccaaata tcataatggc aagtaagaac tgtaaagacg gctctatata
    19261 ttgcgccagt ccggtgacaa tcaacgaggt gtgatttaac gcgatggcaa ataataccag
    19321 tggaatgatc gtcactggcg ccgtcatgac atacaaaaag aaaggagtat tagcggatat
    19381 aattggtcca gtatcgctaa agagaaaaat taatagtgag acaggcaatg cccataatgt
    19441 ttcaatcgtt atcgatgtca tcacatcata atgtataaac tttcgcgcca ggccatatag
    19501 cgcaaatgat aatcccatgg ttagcgccag cgccgggaaa tgccgtagca tgataatttg
    19561 aaaagtcagg ccacagacac cagaaaaaac ggcgatggcc tgaaacaacg acagtttttc
    19621 tttaagaaaa atgcatccca gcgcaataac aaatagcggg ttgataaaat agccgaggct
    19681 ggcatcaagt accagatgat gggttagcgc ataaatgaaa gatgaccatg agacaatcat
    19741 caaaagtccg gcgatcatgc agaagaaaaa ggatttttta tctttccagg catcatgaaa
    19801 tcgcgttcgc tgccgaaata acaaccttac tgccagtaat aatggaattg accagaacac
    19861 ccggtatatc aatatttgtg cgagatttcc ccctgataaa tattgataat ataaaggtgt
    19921 taacccccat aatataaatg ccagcaccac aaacatggta ccgctacgca gatatttttc
    19981 cacttatcca tatcctgtta taacttcacc cgatgcgtat gaattttcca gttctcctgc
    20041 tacgctacat cgagtggttt tatttactct aaaatcttca cgccatttta acatggattc
    20101 taacattgta atttcattgt gatagctgat aaaaatcaaa agaatgttta tcagggaaat
    20161 ctgatgccga aactaataaa gtgactggat tattttatct gcatcgcctg accgccgcgg
    20221 acggcgctgt caggcgacag aatatttacg ctatttcaac ccttatgcgt tgcggcaaca
    20281 atcgcttcgc tcagcgcgtt cagcccctga ctgcgtgagg cgctaagctg ggcgcgtaaa
    20341 cccagctcat caaacagcgc cagcggtgaa cgagcctgca actcggcggc gttttttcct
    20401 tccaccgcgg tgagcaatac cgctagcagg ccgcggacaa tccgcccctc actgtcgccg
    20461 aaaaagtgca tcgttccgtt atctgatcgg gtaaagccca gccagacgcg gttctcgcag
    20521 ccggctatct ccttcgcctg cgctttgcat tcatccggca gagcggggag ctgttttcct
    20581 aacagaatca actgacgata tttatcctcc cattgggtca gcgggagaaa gatagcgcgt
    20641 aacgtctctt ccgttaccgt tgtgccgaac gggtgtccgg tataaagagg gtttgtcatt
    20701 aatccaccag cagttccagc gcgcggtcaa cggcgttaac caacgcatcc acatcatgtt
    20761 gggtattata cggcgcaaaa gaggcgcgca gagtccctgt gacgccaagt tccgctagca
    20821 atggctgggc gcaatgttgc ccggcccgga gcgcaatacc gtattccgcc agcagcgtca
    20881 ccatatcgcc gtggtgcacg ccgacaaaat caaaggccag caggctggag tcctggcagc
    20941 ggaacgaacg aaagcccgga cgtttcgcca gtgcgtcttc cgccagcgtc gccagccccc
    21001 ggctccagtt ttcggcctgt tcaatatcga tatcggacag ccattccagc gcagcgctca
    21061 ggccgatgac cccggcgacg ttcggcgtcc ccgcttccag tttccaggga gcgctttgag
    21121 tggtgaagcc ttcaaagcta acgtcacgga tcatcttgcc gccgccgagc cagggcgaca
    21181 tcgcctcaag aagctccggc ttaccgtaca gcacgccgat accggtcggg ccatacagtt
    21241 tgtgagcgga aaaagcataa aaatcgatat caagctgctg gacatccgcc gggaagtgta
    21301 cagcgccttg cgcgccatct atcatcacga ccattcccgc cgcgtgagcg gcgctgatag
    21361 cgcctgtgag atccggacag ccgcccgtta cgttcgacat ttgccccagc gccagtatcc
    21421 ggctgcgcga cgtgatcagt tccggcagac gctcaacatc aggaagacgt cggtcattaa
    21481 gcggcagttt tatgacctgc gcgccggttt gttgcgccac catcagccag ggaacaaggt
    21541 tggcgtgatg ctcggcgacg ctaacgataa tttcatcgcc ggggcgcaga cgaggacggg
    21601 cgtaacactg cgccaccatg ttgatcgctt cggtggtgcc gcgtgtccag acgatacttt
    21661 tttcatcggg cgcgtttaac agccgcgccg cttttgctct ggccgcttca tattgcgccg
    21721 tcaggcgctg cgcctgcgca aactggctac gatgaacgtt accggcgctc aaacaataaa
    21781 actggtgcgt ggcgtcaatg actgcctgtg gctttaatgc cgtggcggcg ctatcgagat
    21841 aaacacccgc atcggctagc gcgggaaact gcgcgcgaaa ctgcgtggga ttaaaagcgt
    21901 tcatgatatt cctcggttca gtttaccgat cgtggcgtaa aagcgcggct gatacaaggt
    21961 ttgtcctaac catcggaatc gtctgtatat cctggcgaat tatgtaaagg aggttatgct
    22021 gaataatgtt aggcgaatgt ttaagcctgt tacggagtcc gctttaaata gcacaaacag
    22081 ctttaaggag aagaagatga aaaagactgc cgcaattatc tctgcatgta tgctgacttt
    22141 tgccctgagc gcctgttccg gtcctaatta cgttatgcac accaatgatg gacgtagcat
    22201 tgtgaccgac ggtaaacccc agaccgataa cgataccggt atgatttcgt ataaagacgc
    22261 taatggcaac aaacagcaga tcaatcgtac tgacgtgaaa gagatggtgg ctctggaaaa
    22321 ctaaccgttt gttatacaaa aaaaagcacc gcaatatggc ggtgctacat taatcactat
    22381 ggacagacag ggtaaatgta caggaagtga aaaagggtag tctcgctacc gtggtctgaa
    22441 tcgcagacca attgcaaaca caacaacaca acatcacaac cgtaagccaa aagcccatca
    22501 gaacacgcat tccgataaaa cttttcgttc cggctcagga agtgccgcca ctataggtat
    22561 ttgctggtag aacctcaacg gacaatttat aatgtctcag attaaaaaaa ctaataggtt
    22621 acctattgtt acctatttgt taaattcatt cgacattaag tccagaggcc atgtcaaaac
    22681 gattacctcc tttaaatgcg ttacgcgttt ttgatgctgc cgcgcgccat ttgagtttta
    22741 cgcgagcagc ggaagaactt tttgtgacgc aggccgcagt aagccaccaa attaagtcac
    22801 ttgaggattt tttggggcta aaactgttcc gccgccgcaa tcgttcgctg ctgctgacgg
    22861 aagaaggcca aagctatttt cttgatatta aagagatatt ttcccagcta acggaagcaa
    22921 cgcgtaagct ccaggcgcgc agtgccaaag gggcgctgac ggtgagttta ccgcccagtt
    22981 ttgccatcca gtggctggtg cccaggctct ccagctttaa ctcagcttat ccgggaattg
    23041 acgttcggat acaagccgtt gatcgtcagg aagataaact ggcagacgat gtcgatgtcg
    23101 cgatttttta tggccgggga aactggccgg gcttgcgcgt cgaaaaatta tacgcagaat
    23161 atttattgcc cgtctgttct cctttattgc tcacaggcga aaaaccgtta aaaacgccgg
    23221 aggatctggc gaaacatacg ttattgcacg atgcctcccg gcgtgactgg caggcctata
    23281 ctcgtcagtt agggctcaac catattaacg ttcagcaagg gccgatattt agccacagcg
    23341 cgatggtgct acaggcggct attcacggac aggggatcgc gctggcgaat aatgttatgg
    23401 cgcagtcgga aattgaagcc gggcgactgg tgtgtccatt taacgatgtt ctggtgagta
    23461 agaatgcttt ttatctggtt tgtcatgaca gccaggcaga actgggtaaa atagccgcct
    23521 tccgtcagtg gattttggcg aaggcggcga cggagcaaga aaaattccgt tttcgttacg
    23581 aacaataatt aacttagggt atgaccatga ccagccgttt tatgctgatt gtcgccgcta
    23641 tcagcggttt tatttacgtt gctctgggcg cgttcggggc gcatgttttg agtaaaaccc
    23701 tgggcgtggt tgaaatgggc tggattcaga ccggcctgca atatcaggcg ttccatacgc
    23761 tggcgatctt tggcctggcg gtggcgatgc agcgccgtat cagcatctgg ttttactgga
    23821 gcagcgtttt tctggcgctg ggcacggtgc tgtttagcgg cagcctgtac tgccttgcgc
    23881 tttcgcatct gcgcctgtgg gcgtatatca cgcctgtcgg cggcgtcagt ttcctggtgg
    23941 gctgggcgct attgctgatt ggcgccattc gtatgaaacg taagggcgcg agccatgaat
    24001 aaagttgtct tgctctgccg tccggggttt gaaaaagagt gcgctgcaga aattaccgat
    24061 aaagcgggaa aacgggaaat atttggtttt gcacgcgtaa aagagaacgc aggctatgtc
    24121 atttatgaat gctaccagcc ggaagatggc gaaaagctga tttcagaact gccgttcagt
    24181 tcgctgattt tcgcccgcca gtggtttgtg gtgggtgaac tgctgcaaca tttaccgccg
    24241 gaagacagaa tcacgccgat tgtcggcatg ttgcagggcg tagtggaaaa gggcggcgag
    24301 ctgcgggttg aagtcgccga caccaatgaa agtaaagaac tgatgaagtt ctgccgcaaa
    24361 tttacggtgc cgctgcgcgc ggctttgcgt gatgcgggcg tattgacgaa ttatgaaacg
    24421 ccgaagcgtc cggtcgttca tgtctttttt atcgcgccag gatgctgcta taccggttat
    24481 tcgttcgcgc ataacaattc accgttttat atgggcatcc cgcgtttgaa gtttccgtct
    24541 gatgcgccga gccgctcaac gctgaaactg gaagaggcgc tccacgtttt catcccggaa
    24601 gatgagtggg atgaacgtct ggcaaacggc atgtacgcgg tggatttggg cgcctgtccc
    24661 ggcggatgga cgtaccagtt agtgaagcgc aatatgtggg tctactccgt agataacggc
    24721 ccgatggcgc aaagcctgat ggacaccgga caggtgacct ggttgcgtga ggatggcttc
    24781 aggtaccgtc cgaaccggaa taatatttca tggatggtct gcgatatggt ggagaagccg
    24841 gccaaagtca ccgcgttaat ggcgcagtgg ctggtgaacg gctggtgtcg ggagacgatt
    24901 tttaacctta aactgccgat gaaaaaacgc tatgaagagg tatcgcataa cctggcgtat
    24961 cttcaggcgc agttggatga gcatggcgtt aatgcgcaga tccaggcgcg tcagctttat
    25021 cacgatcgcg aagaagtgac ggtacacgtg cgtcggttgt gggcggctgt tggcggacgt
    25081 cgcgacgagc gataaaaacg cgctgccgtc atccggcgcg tcatcagcgc cggatggcgc
    25141 acgcttatcc ggcctatgac tgcggcgcat ctgaaacgat atgcgtcaca tcatccagat
    25201 ggccgatgcg cgcctctcct gaacgattaa atttactttt atcaatcaat aataaagact
    25261 gcgaggcgcg cctgagcagg atagatttaa aatcggcgtt gatcgcattg gagtcccaca
    25321 gatcgccgcc gccgtcgatc ccctcgcagg aaaagatgaa cagatcgata tcaagcgatt
    25381 ttagctgtga gataagcgac ggattaacgt aacagccata tttacgttca agctggccgc
    25441 cggaacttat cagcgcaatg cgttcgcgtt ttcccagctc ctgacagata ggatggctat
    25501 tggtaaaaac ctgaatggga atatccggca actggcgggc cagataccag caggttgaac
    25561 tggcatccag cgcaatcgtc attccttctt ctatccacgc taacgcttca cgggcaatat
    25621 cggctttatg cgcataatgg cttttcaggc ggatatggaa tggatcgccg ctgtcctgat
    25681 tttcacgatg aatatattta gctcgtccgt gattacgcag cacttttccc tgcgtctgta
    25741 gttcactgag atcgcggcgg atggtctctt tactgacgtt aagccgggtg gccagcgctt
    25801 cggtggtcag acttttatga ttgatcagca gatcgactat cgcttgttgg cgtgccgctt
    25861 tcatttttct caccccatca ttcgatgaac gcccgcgtca tgcgggcgca ccggcaagag
    25921 attacggcgt tacccctttt tttaaaagaa tatttccgta cttcgcgcac tcacctgtga
    25981 taacgatcgc aaacgctttt tgcgcccgct cataaaacgc atagcggtcg atacgaacga
    26041 tatccgggca cggcgcttct aatgacaaag catcgcgata acgcgcttca acgctggggt
    26101 cgagcgtgtc gccttctacg gcggccatca tcaccagcgg cggggcgtag ctatccagct
    26161 caaagagcgg aatgattgcc cgcagtagat cgctgacgct aagaccatcg gcgcgaatca
    26221 cctgcgggcc caggctatgc gcgggaaagt gagcgtcaga aaaaatgatt tcgtccccgt
    26281 ggcccatctc ggccagcact ttgagcagtg tcggggaaat taacggtgaa atggttttta
    26341 gcatttcata ctccctcaat aatttcaggt tcggtttgcg gccagaaata gcgatactga
    26401 taattgacct gcgcacgcgc ctgctccggg ctactaaatt cgcctacgcc gtaccagcca
    26461 aacatggcag cgccggccac ggtggtttcc gcgtcgtcca gcactttgat agggatatca
    26521 agttgattcg ctttaatttg attccacaaa gcgttgcgac tgccgccgcc aaccagtaac
    26581 agttctgtgg cgttaaaatg gccgattttc tccagcgtgc gcagattacg ctgaagttgc
    26641 gccgtcaggc cttccagcgc ggcgcgatag aaatggccgc gggtggtatt gagcgtcacg
    26701 ccctgccagc ctgcattttg acaggcgagc agatcgcact gcatccgcac gccttccgcg
    26761 ccagcgggaa tagcgcgcgc ttcgtcgatc agcgtttgcc atggcgtttc cggcgtccac
    26821 agcagttttc gtacccattc gagtacgccg gaggccagcc actgcattcc ggggttataa
    26881 agccccgact gactgtccag ttcacaggtc gagcccggat actgactgag cagcgaggta
    26941 tccacctgac cgctgcgcac catcagaatc tcccatgttc cggaggagag cactggttca
    27001 ccttgctgcg cgccagcgcc gaataacgcg aactgagtat cgtgttcggc agagatcact
    27061 ggcacacccg ccgggagacc gagtagcctg gccgcgtctg tctgtagcgt gcctatcggg
    27121 gcgcccgctt ccacgatacg cgggaacagg cggcgcgcca ggcccgtcgc ctgcaggatt
    27181 tccggactaa agtcgcgctg atggatatcc agtagctggc tggtgcctgc catagtgata
    27241 tcggtcgtaa actctccggt cagacggtgg ttaatcagcg acgagataaa cagccagcag
    27301 tgagcttgtt ccagcaggcg cggatgattc tctttaagcc agaccagttt atacagcgtg
    27361 ttaaagctga acgcgccgac gccggagagc gtctgcaatt gccggggcga gataaagcgc
    27421 tcaatcgttt ccatcacggc agcggttcgc gggcatttcc aactgatgac cgggtagagc
    27481 agcttaccct gcgcatcgac cagcgcgcca tcgacgccga aagtagtcac cgtaataccg
    27541 cgaacaacac actccgacag ggcgctggag agtgacctgc agcagtcggc gaaacgttgc
    27601 aggatggcgt ccagcgacca ctgatgccag gcgctatttt ctgcggcaat gtcgctggcg
    27661 ttagcggttg aggcgcgggc gacaattttc ccctggcgat caacggcgat cgcccgaacg
    27721 ttagtcgcac cgcagtcgag aaccaggata acgtcttgtt tcatagataa ctccataaac
    27781 gccgcctgat ggcgctacgc ttatccggcc tacggttcac gcgcccgtag gcccggtaag
    27841 cctgcgccac cgggctaagc cgcattaacg tttatacagc gggccataat tctggcaggc
    27901 gcgataatcc tagccttcga tatccatacc gtgagccgcc caggcggaag gacggtagat
    27961 cttcgcctcc tccacgttgt gcatacatac cgggatacgc agcatcgcgg cgagagtaat
    28021 aaagtccgcc cctacatgac cgatggtgag tacgccgtgg ttagcgcccc agttcgccat
    28081 caccgaatag acatcggtaa acggaccttt gccgataaga cgcggcgcaa accaggtggt
    28141 aggccaggta gagttggtgc gggcatcaag ctgatcgtgc atcgctttcg gcagttcgac
    28201 gctccacccc tcggcgattt gcagtactgg tcccaggcct ttgatgatat tcacgcgggt
    28261 catggtgaat ggcacgccgc cttcggtcag aaaacgggat gagtagccgc cgccgcggaa
    28321 gtattcgtga attgccgggc accattcagt ggccgccaga cacgcatccg cctcttgttg
    28381 gctgatttcc cagtgcggtt tcatggtcgg cttgccttcg ctgtcgcgct gtttacaggc
    28441 accgtccagc gcggcagaac cggagttaat caggtgaata atgccgtgtt ccgccagggc
    28501 gctgagcgcc tggccggtga cgcgttctac ggcttccggc gaccagtaag ttcgcacgtc
    28561 ggcgaatatc tgcgcggtac cggtgagttg atggccaaac agcatcgcta ctccgttcag
    28621 actgtcattt tcggtggcga cgacaaacgg ttcgcgtacg ccgttccagt caaaagagct
    28681 attgagcagc gcttcggcgg tatcgccgtt cgggtattga tcggtccagt ggcgctggcc
    28741 ctggaagccg gcggcaatgg cgttgtagcc cagcgattct tcaactaacc ctttgtccgc
    28801 cagcgtcttg ttgccctgca tcatgtcgcg aatacacatc gccatcagca ggctctcttt
    28861 tagcaccgcg cggttctggg cttcattgcg cttatactgc gaggcgtttt gatcttcgcc
    28921 gtagcggaag tttttatccg cccacgccag cgccatctcc agttcggcct catcataaat
    28981 tttttgatcg atacggcggc gcagttcggt catatctacc gcttgcacct tcatgcccag
    29041 ccaggattca aagaagttat gatcgacaat ggaacccgcg atccccatcg acacgccgcc
    29101 gacggagagg tagcttttgc ctttcatgct ggctaccgct aaccctgccc gcgcaaaacg
    29161 cagcagtttt tcttcgacgt cggcaggaat ggaggtatcg tcggcatcct gcacgtcatg
    29221 gccataaatg gagaacgccg gaatgccttt ttggctgtgc gccgccagcg ccgcggcaag
    29281 gtaaaccgcc ccgggacgct ctgtgccgtt aaagccccag atggctttcg gacgcatcgg
    29341 gtccatatca atggtttcgc tgccatagca ccagcacggc gtaacggtaa tggtcacgcc
    29401 cacgttctgg ctactgaatt tttcttcaca ggcggcggat tccgccattc cggcaataca
    29461 ggtatccgca atgacgcact ccacctgtgc cccacaggcg tggcggattt tctcggtgat
    29521 gagcgccgcc gtcgctttcg ccatgttcat ggtttgctct tcgagcgact cgcgtacgcc
    29581 catacgacgt ccatcaatca ccgggcggat accgattttc ggtaagctga tttttttcat
    29641 gacagattcc tcacgttatt cggataaatg ttcagtttgt cgccgcttgt gaacggaaac
    29701 gggcaaaaat gaagatgacg gcaaagcaca atgccggaac cagttcggcg gtcgggattt
    29761 tgcctgcggc gtcgctaacg aagcccatta ctggcgtgac aataccgccg ccaataatgg
    29821 tcatgacgat aaaagacgag ccgtacttag tgtcctgtcc cagatttttg atacccagcg
    29881 agaagatggt tgggtactgg attgacataa atgcgctaca caacgtcagc gccagcaggc
    29941 cgatatgtcc gccgctaaag gcggaaatca gacacaggag catggcaagc agggcatagg
    30001 cggccagcac tttatgcggc gcgaagcggc tgataagcca ggtcccggtg aaacggccga
    30061 taaagaagca caccatcgtg ccggtcaggt agttggcggc gaaaccgggc gtcattccag
    30121 ggatctcctc aatggcgtag cggatcagat agctccagca ggcggtttgc gcccccacgt
    30181 agcagaactg cgccagcacc gcccagcgcc agtggcggat acggatgagt cgggagagag
    30241 aagataagaa agagctttgt ttagcatcgc tatgatcgtc actttgcagg gccggaaatt
    30301 tggtcagcat aatcagcagc gcaactacta atacgatggc gacgataatc atgtatggcg
    30361 tttgtaccga taacaccagg ctgtgtttat aggcgctaag ctgatccggc gtcattttat
    30421 caagcgcttc ttgtgattga tgcggcacgt tagacaaaat aaggctttgc ccaaacacaa
    30481 cggcgataat agcgccaaag gagttaaaag tttgcgccag attaagccgg aaatgtccgc
    30541 cgctttctgg acctaatgcc gtcacaaaag gattggccgc agtttcaagg cagcctaaac
    30601 cggcggcgat gataaacagg ccaattaaaa ataatgtgta attcattatc tcggcggcag
    30661 gccagaataa tgcggcgcca aaagcataca aaaaaagtcc agtgataatc cctgctttat
    30721 aactgagttt tttcatcaaa atcccagcgg gaattggaat gacgaaataa ccgaaataaa
    30781 aggctgactg aataagtccg gcctggaagt tagttagcgt aaaagcttgt tgaaactgcg
    30841 gtaataaaat gtcattcaga ttattggcga cggcccacag aaaaaatagc gagcaaagta
    30901 aggcgaatgg aataatgtag cgcttgcttt tgctttgctc tgcatccaca gcacgaaaac
    30961 tctgtgtttg tattgttgtg tttcccatag catcctcatc ggttcagaag cttttgcgtg
    31021 cggtcggttc tggtcaccag accgtaaaat taggtgagtt cgcttttctt accggtaata
    31081 aattggcgtc cggaatgaac tcatggagtc attttcaaat aaaaaaggcc ttttaatatg
    31141 atggcggtca catttatacc tgagagcata gcgttctgtg attatcatca ctttaatttt
    31201 cataaaaaaa tgaccgtttg agatgtttaa tttaaaaaac cacaggctga atgcccgaat
    31261 taaattattg ctacgaaaac ggtcagtggt aacttatttt tcatctttgc ccgttttgaa
    31321 aaatattatt aagagcgggc atttatcggc gagagaaatg gcagtcgtct ggtttatcgt
    31381 ggcgaattaa ttgatgtgta tcacaaaata ttgttattta aattcccttc tctttattca
    31441 gtatgatgat agttgctaac tattcgatta tttcaacagg acagcagcgt gatgcgaaag
    31501 gcggttttgt tgtctcattt tgaatcacag agagaggtaa ataatggaac gaaatagact
    31561 ggctcggcag attattgata cctgtctgga aatgacgcgg ttagggttaa atcaggggac
    31621 ggcaggtaac gtgagcgtac gttatcaggg cggaatgctg attacgccga cggggatccc
    31681 ctacgagaag ctgacagagt cgcacattgt ctttattgat gcagacggtc agcatgagca
    31741 gggcaagctg ccttccagcg agtggcgttt tcatatggcg gcataccaga cgcgccctga
    31801 cgccaatgcc gtggtacata accacgctgt ccattgtacg gcagtctcga tcctgaatcg
    31861 cccgattccg gcgattcact acatgattgc cgccgcgggg gggaactcta ttccctgcgc
    31921 gccctacgcc acttttggca cccgcgaact ttctgaccat gttgccgtgg cgcttaaaaa
    31981 tcgtaaagcg acgctgttac agcatcacgg gcttatcgct tgtgaagaaa atttagacaa
    32041 agcgttgtgg ctggcgcatg aagtggaagt gctggcgcag ctctatttaa gtacgctggc
    32101 cattgtcgat ccggtaccgg tactggatga cgaggcgatc gctatcgtac tggagaaatt
    32161 taaaacttac ggattacgta ttgaagagtg atgtcaggag acaggcgatg gcgaacagaa
    32221 tgattctgaa tgaaacggca tggtttggcc ggggagcggt ggacgcatta accgatgagg
    32281 tgacgcgccg cggttatcat aaggcgctga ttgttaccga taaaacgctg gtgcaatgcg
    32341 gtgtggtcga taaggttaca agcagaatgg atgccgcagg gctggcgtgg gagatctatg
    32401 cgggcgtgat ccctaatcct acgatttccg ttgtccagga agggcttaag gtctttaccc
    32461 aaagtggcgc ggactatctc atcgccattg gcggcggttc tccgcaggat acctgcaaag
    32521 cggtcggtat tatcagtaac aatccggaat ttgccgatgt gcgcagtctg gaagggctat
    32581 cgccgacccg taaacccagc gtgccgatta tggcgatccc gacaacggcg ggaaccgcgg
    32641 cggaagtcac tatcaattat gtgattaccg atgaagagaa acggcgcaaa ttcgtttgtg
    32701 tcgatccgca tgatattccg caggcggcat ttatcgatgc cgatatgatg gacggtatgc
    32761 cgcccgcgct gaaagcggca acgggcgtgg atgcgctaac ccatgctatt gaaggctata
    32821 ttacccgggc cgcatgggcg ctgacggatg cattacatat caaagccatt gagattattg
    32881 ctggcgcgct gcgcggcgcc gtagccggag aaaaagaggc cggtgaggcg atggcgctgg
    32941 ggcaatacgt tgccgggatg gggttttcca atgtggggct gggactggtg catgggatgg
    33001 cgcatccgtt gggcgcgttt tacaacacgc cgcacggcgt cgcgaatgct attttgctcc
    33061 cgcatgtgat gcgtttcaat gccgggtcta ccaacgagaa attccgtgat atcgcccggg
    33121 cgatgggggt gaaggtagaa ggattgagcc ttgaagaggc gcgtaatgcc gcagtggaag
    33181 ccgtatttac gctaaatcgc gatgtgggaa ttccgctgca tttgcgtgat gtcggcgttc
    33241 gaaaagagga tatcccggcg ctggcgcagg cggcgttcga tgatgtctgt acgggcggca
    33301 atccgcgtga agcgagtctg gcggacattg tcgaactgta tcataccgcc tggtaatttt
    33361 gccggatggc gctgcgctta tccgctctac atttcgtgca gttctgtagg ccggataagg
    33421 cgttcacgcc gccatccggc aacaaaacta ccgtaccagc cgtagctgct gtaagtttcc
    33481 gtcgatatgt aaatcggttt gcagacgtgc aatatcgcgg caaagaaatg ccatttcttt
    33541 atgcgtctca agctttttgc gccacttttc cggcacctcg tccagatggg cgtaaattcc
    33601 ctccagattt tgaaactgaa ccaacagctg ggtcgcgctt ttagggccga taccggcaac
    33661 gccggggact ttcgaactac tgattcctgc cagaccccag taatccggca actgccgggg
    33721 gagtacgcca aactcttttt caataaacgg cgcgtccagc cagcgtttct ggaagtagtc
    33781 gcgaatgcgc aatcccggag agagcaactg gcaatagcct ttatcggttg acacaatggt
    33841 tgcctggtgt ccggcttcgg taacttttag cgccagcgtc gccgccagat cgtccgcttc
    33901 gttaccgtct gatgcccaac agcgtacgcc gcgctgttca aacgcggcgc gtagggcggg
    33961 catttcatta tgtaaatcgt caggcatcgg cggacgtcct gctttgtagt ccggcaaacg
    34021 ctgatgacgc cagccgctgc tgcgcgcgtc gtcatcaaat accgctacgg catgggttgg
    34081 ctggctgtgg ataatcaatt gatcgagcgc gtgttggcag gtttccacac agggcgatcc
    34141 ctgaacggcg tgaatacggc gaatcaaatt gagcgcgtcg acgataagca gatgagcagc
    34201 cacggtgttc tcccttacaa acctgcgcgt agggtaacat tcacggcggg gggaggcgag
    34261 cattgcgaaa tcgcgctatc cgtagacctg ataagcgaag cgccatcagg caacaaaagc
    34321 cggatggcgg cgagcgcctt atccggccta cagatcctaa aatgtgctga gaattaatcg
    34381 caggtaacga tcttcatcgc caggccgccg cgcgaagttt cgcggtactt agcgttcatg
    34441 tctttaccgg tttcgtacat ggtctcaatc actttatcga ggcatacgcg cggttcgctg
    34501 gttcggcgca gcgccatacg cgcggcgttg accgctttga ctgaagcaat cgcgttacgc
    34561 tcaatgcagg gaacctggac ctgaccggca accggatcgc aagttagccc cagattatgc
    34621 tccatggcga tttctgcggc gatacacacc tgcgccggac taccgcccag cagctcggcc
    34681 agacccgctg ccgccatgga acaggccacg ccgacctctc cctgacaacc cacttcggcg
    34741 ccggaaatag aggcgttcat cttatacagc gagccaatcg cgctggcgac cagcatatag
    34801 cgagcaagtg agttagcatt tacttcgcgg ataaatttgt catagtacgc cagcaccgcc
    34861 ggcacaatac cacatgcgcc gttagtcggg gcagtgacta ctcgtccgcc tgcggcattc
    34921 tcttcgttca ccgccagcgc gaacatattg atccagtcga cgaccgccat cggatcggtg
    34981 gtggtcttat cctgactgac cagcatccga cgcagcgccg ccgcgcgacg cggaacgcgc
    35041 agtttgcccg gcaatacgcc ctcggtggtg ataccgcgct caataccgct gcgcatcacc
    35101 tcccagacct tggcgaagtg ctgctccagc gcttctttac tgtgcagagc cagttcgttt
    35161 tgcatcatca gaccggagag cgacagaccc gtctcctggc aatggcgctg taaatccgcg
    35221 gcggttttat aaggatacgg tacgttaacg ggttcgctat ttgtcaaacc aaagtgctct
    35281 tcatcgacga taaagccgcc gccaatggag tagtaggttt ggctgtagag cactttattg
    35341 cccgccagcg cggtaatacg catcccgttc tcatgcagag acaggttgtc ggcgtggaaa
    35401 ttcatgcact tatcgaccgg aaattcgact tcatgctgcc cattggccag tagtaaacgc
    35461 ccatgggtgt tcacatcctg gataaaggac ggaatggcgt cgatatcgac ggtgtccggc
    35521 agattccccg ccaggcccat aataatggcg atatcagtgt ggtggccttt acccgtcaat
    35581 gacagagagc cgtagacatc caccacgacg cgggtgacat ctgtaagaat atggcgggca
    35641 atcagatcgt ccgtgaactg cttgcctgct ttcattggtc cgacggtgtg agaactggaa
    35701 gggccaatgc cgattttaaa aatatcgaat acgctaatca tagggcatcc attgcggttg
    35761 tatcatagag aagcgccgcg gtaagcggcg ctaaaggact tagctgaaca gtgagtagaa
    35821 aatagcggag atggcaatca ggcccataat cacaacgaat acgttgctga tatgaccgct
    35881 gtacttacgc attgccggta ctttctggat ggcatacatc ggcatcagga acagaatcat
    35941 cgcgatgatc gggccgccca gggtttcaat catgcccagg atgctggggt tcagcgtcgc
    36001 cacaatccag gtggtgacca gcatgaacag cgcggtaatt ttattcagtt tgttgatttc
    36061 gatggattta cctttaccac gcagcgattt aatcaccatc ccgttaaagc cttcacgcgc
    36121 gcccaggtag tggccgagga aggatttggt gatagcaatc atcgcaatga tcggcgccat
    36181 ccaggcgatg atcggcgcgt taaagtggtt cgccaggtaa gacagaatag agatgttctg
    36241 ctcttttgcc gctgccagat ctgccggcgt caggctcagc acgcagctga agacgaagaa
    36301 catcacggtc agcaccatca tgatgtgggc gaaggccaga attttagaac atttcttctc
    36361 agcgccttca ccgtactctt cacgcttcgc aaccgcgaag gaggagatga tcggggagtg
    36421 gttgaaagag aaaaccatca ccggaatcgc cagccacagc gtcatccaca gaccgttacc
    36481 ggtagacgcg gcggaatcaa aggacagagt ttccagcgcc gcgccgttcc actgcgggat
    36541 caggtacaag gccagcagca tcagcgcagc gacgaacggg aataccagga tactcatcgc
    36601 cttaacgatc atttgctcgc cgaagcgcac gatggtcatc atgccaacaa tcaggatcag
    36661 ggaaagaatc gcccgcggcg gcggattaat cgctaactgg tgggtcagga agctttccac
    36721 ggtattagta atcgccacgc tgtaaaccag caggatgggg taaatcgcga agaagtagag
    36781 cagggtaatc agtttacctg cgccgatacc gaagtgttcc tcaacgactt cagtgatgtc
    36841 ttcacccggg tttttaccgg acagcacgaa gcgggttaaa ccacggtgtg cgaaaaaggt
    36901 catcgggaaa gcgagaatcg ccatgatgat gagcggaatc atgccgccga cgcctgcgtt
    36961 gatcggcagg aacagaacgc ccgcgccgat tgccgtgccg taaaggccca gcatccacat
    37021 ggtatccgtt ttgcgccatg cgcttcgaga gtcaatcgaa gcaatcgtgc tggtctgagt
    37081 ggttttcatc tatttctcct ggaggatgct aaaaatcagg ttgctggtct aatccaatga
    37141 aaaaagacct gatcgtaaaa tgaaatctgc ttagggacgc tttttatata atttttcgcc
    37201 gtaataattt tcgggcggaa agatacattt aagtgatgaa tctatcagtg atcccgatct
    37261 caaatgcaat aatccgcttc ttacatggat aaatttggac cattaatcta ttaaaaaaac
    37321 gtcataacga atttccgggc gcgaaggcta ccattaacga tataaggccg gaaagattgg
    37381 ggcgcaagat acggag
//
LOCUS       DAJVKX010000035        36068 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000035 DAJVKX010000000
VERSION     DAJVKX010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 36068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36068
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.035"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..439)
                     /locus_tag="OPY25_001741"
     CDS             complement(<1..439)
                     /locus_tag="OPY25_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927374.1"
                     /translation="MKKRSLLLLALPAMAFSTWAATSPPANLSPVYSYQDDVPSAATP
                     PVATTPVAKPASTSVLPFLGDEARKRGYELPEPFGLNINYMNIGQNINVDSINFNGLA
                     LGPNGGIPLDNAFKINVGHTREKSKTETVKLDAWLLPFMNVYGL"
     gene            complement(641..1453)
                     /gene="yidA"
                     /locus_tag="OPY25_001742"
     CDS             complement(641..1453)
                     /gene="yidA"
                     /locus_tag="OPY25_001742"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCS0927375.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAAREKGVNVVLTTG
                     RPYAGVHSYLKELHMEQPGDYCITYNGALVQKAGDGSTVAQTALSYDDYRYLEKLSRE
                     VGSHFHALDRNTLYTANRDISYYTVHESYVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AVLDRAIARIPAEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLAEALGIKPEEVMAI
                     GDQENDIAMIEYAGMGVAMDNAIPSVKEVANFVTKSNLEDGVAWAIEQHVLS"
     gene            1742..3004
                     /locus_tag="OPY25_001743"
     CDS             1742..3004
                     /locus_tag="OPY25_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0927376.1"
                     /translation="MSMALTAPPGRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFL
                     AYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALIIGG
                     VATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
                     PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQET
                     ESASSSESFMLRVKPVITNYCYWLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEM
                     GWLASLPFVLSIFSKAAAGVFVDKIGRSAPILMVLMFFAGISIYFGTITEHKYMSAVL
                     LSFAVAFCTMGTPVAWTLLQGMVSGKSISAASGVMNGVANGLSSLSPVFIGLFISITG
                     TYTGGLLCLVFISAIAVVSAFVLTIKKY"
     gene            3018..4211
                     /locus_tag="OPY25_001744"
     CDS             3018..4211
                     /locus_tag="OPY25_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HCS0927377.1"
                     /translation="MMKITSIDIIDVANDFASATSKWRPVVVKINTDEGISGFGEVGL
                     AYGVGASAGIGMAKDLAAIIIGMDPMNNEAIWEKMLKKTFWGQGGGGIFSAAMSGIDI
                     ALWDIKGKAWGVPLYKMLGGKSREKIRTYASQLQFGWGDGSDKDMLTEPEQYAQAALT
                     AVSEGYDAIKVDTVAMDRHGNWNQQNLNGPLTDKILRLGYDRMAAIRDAVGPDVDIIA
                     EMHAFTDTTSAIQFGRMIEELGIFYYEEPVMPLNPGQMKQVADKINIPLAAGERIYWR
                     WGYRPFLENGSLSVIQPDICTCGGITEVKKICDMAHVYDKTVQIHVCGGPISTAVALH
                     METAIPNFVIHELHRYALLEPNTQTCKYNYLPKNGMYEVSELPGIGQELTEETMKKSP
                     TITVK"
     gene            4326..5234
                     /locus_tag="OPY25_001745"
     CDS             4326..5234
                     /locus_tag="OPY25_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0927378.1"
                     /translation="MNLTIRQFRAFLAVADLRSFTAASKYLCITQGAVSGLINEMESQ
                     MEVSLFDRTSRVVKLSPDGEKFLPAAMRVVEEFQRAENYARDLKEIKKSLVRVVGAPL
                     IACAFLPQIIHAFKRQHPHTHVQLIDKPMSQLQKSIMLGEADFGIGPERPLEPEIDKQ
                     TLFTTEIALYCHPDYRLHKKTVRWEEIQSEELIAVGNESVPMISATAGVRIKPKMTVE
                     HMATAMSLAAQCEGVVIAETFSRHYAKSYQLATCSLTPPLRRNMNLYFHAWRAQTPAT
                     QRFKEFLFRYMDEHHDALASQRRAGD"
     gene            complement(5241..7655)
                     /gene="gyrB"
                     /locus_tag="OPY25_001746"
     CDS             complement(5241..7655)
                     /gene="gyrB"
                     /locus_tag="OPY25_001746"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCS0927379.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPTGIHPEEGVSATEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT
                     DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQ
                     TVTRWVNALITELNEKEQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFV
                     TGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFEQALEWLVKESRRGLAIQRYK
                     GLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(7684..8757)
                     /gene="recF"
                     /locus_tag="OPY25_001747"
     CDS             complement(7684..8757)
                     /gene="recF"
                     /locus_tag="OPY25_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCS0927380.1"
                     /translation="MSLSRLLIKDFRNIENADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQPGRVIRHEQEAFVLHGRLQGEERETSIGLTKDKQGDSKVRIDGTDG
                     HKIAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLLKQ
                     RNAALRQVSRYEQLRPWDKELIPLAEQISTWRAEYSSAIAQDMADTCQQFLPEFSLTF
                     SFQRGWEKETDYADVLERSFERDRMLTYTAHGPHKADFRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDARRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(8955..10055)
                     /gene="dnaN"
                     /locus_tag="OPY25_001748"
     CDS             complement(8955..10055)
                     /gene="dnaN"
                     /locus_tag="OPY25_001748"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCS0927381.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVTLSQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGDRMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGSELRTVATDGHRLAVCSMPLEASLPSHSVIVPRKGVIELMRMLDGGENPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDILKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVSYGGTEMEIGFNVSYVLDVLNALKCE
                     TVRIMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(10060..11460)
                     /gene="dnaA"
                     /locus_tag="OPY25_001749"
     CDS             complement(10060..11460)
                     /gene="dnaA"
                     /locus_tag="OPY25_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCS0927382.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLNTFCGADAPQLRFEVGTKPVTQTLKTPVHNVVAPTQTTT
                     AQPQRVAPAARSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNP
                     GGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAI
                     EEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEING
                     VEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRE
                     LEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKIAD
                     LLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREES
                     HDIKEDFSNLIRTLSS"
     gene            12121..12261
                     /gene="rpmH"
                     /locus_tag="OPY25_001750"
     CDS             12121..12261
                     /gene="rpmH"
                     /locus_tag="OPY25_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCS0927383.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            12278..12637
                     /gene="rnpA"
                     /locus_tag="OPY25_001751"
     CDS             12278..12637
                     /gene="rnpA"
                     /locus_tag="OPY25_001751"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCS0927384.1"
                     /translation="MVKLAFPRELRLLTPAHFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            12601..12858
                     /gene="yidD"
                     /locus_tag="OPY25_001752"
     CDS             12601..12858
                     /gene="yidD"
                     /locus_tag="OPY25_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCS0927385.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            12861..14507
                     /gene="yidC"
                     /locus_tag="OPY25_001753"
     CDS             12861..14507
                     /gene="yidC"
                     /locus_tag="OPY25_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCS0927386.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQTQQTMQTTTTAA
                     GSAADQGVPASGQGKMITVKTDVLDLTINTRGGDVEQALLPAYPKELGSNEPFQLLET
                     TPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQVPMTYTDAAGNT
                     FTKTFVFKRGDYAVNVNYSVQNTGEKPLEVSTFGQLKQSVNLPPHRDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNVSSKGGWVAMLQQYFATAWIPRNDGTNNFYT
                     ANLGNGIVAIGYKAQPVLVQPGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            14649..16013
                     /gene="mnmE"
                     /locus_tag="OPY25_001754"
     CDS             14649..16013
                     /gene="mnmE"
                     /locus_tag="OPY25_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCS0927387.1"
                     /translation="MSHNDTIVAQATPPGRGGVGILRISGLKARDVAQEVLGKLPKPR
                     YADYLPFKDVDGSALDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTLPG
                     VRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRTEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRD
                     ANDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPADIWPDFIARLPKNLPITVVR
                     NKADITGETLGISEVNGHSLVRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALAEAANHLEQGKAQLLGAWAGELLAEELRLAQQSLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            16196..17383
                     /locus_tag="OPY25_001755"
     CDS             16196..17383
                     /locus_tag="OPY25_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0927388.1"
                     /translation="MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMATAMLFAGKIADQSGRKPVAIVGAIVFMMASLLCSRASEGSLFLSGRFLQG
                     VGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVMGHLIMLRFPWQSLF
                     YTMSTMGIMVGLLSLFILRETRPARLAPRDLSPSSSAAESLVNRFFVSRLAITTLSVS
                     VILTFVNASPVLLMEVMGFSRGDYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVS
                     QGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALGPFSLRAGVASSTLG
                     IAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVAPNRSVAEHEEIPYQ
                     SRS"
     gene            17352..18311
                     /gene="yidZ"
                     /locus_tag="OPY25_001756"
     CDS             17352..18311
                     /gene="yidZ"
                     /locus_tag="OPY25_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HCS0927389.1"
                     /translation="MKKSLTSLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLA
                     KLRAWFDDPLFVNTPLGLAPTPLMVSMEQSLADWMQMGNQLLDKPHHQTPRGLKFELA
                     AESPLMMIMFNSLSQQIYQRYPQATIKVRNWDYDSLEAITRGKVDIGFTGRESHPRSR
                     ELISLLPLAIDFEVLFSDLPWVWLQEDHPALREAWDLDTFLRYPHISICWEQSDTWAL
                     DDVLQEMGRKRHIALSLPGFEQSLFMAAQPGHTLIATAPRYCQHYNQLHQLPLVARPL
                     PFDAQQREKLMVPFTLLWHKRNSHNPKIVWLRQAINTLCRRLI"
     gene            18469..19224
                     /locus_tag="OPY25_001757"
     CDS             18469..19224
                     /locus_tag="OPY25_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HCS0927390.1"
                     /translation="MATHFARGILTEGQLVSIRLSSSCHIEARNLPAHRRTRFLASRG
                     LLAELMFMLYGISELPEIIIQAKGKPAFRDKNLPGFSISYAGNMVGVALTTEGECGLD
                     MELQRTSRGFHHPHSLERHPFSRNENLWVANQNDPNEARAQLITLRQSVLKLTGDVMN
                     DDPRELQLLPVAGRLKCAHVTQLEAVCDAEDVLVWSVTVTPAIEKLKVWEFDGKLGWK
                     SLPDIQTRANEPTGRLMRFAQLPAAKSYTLNRS"
     gene            19224..19808
                     /locus_tag="OPY25_001758"
     CDS             19224..19808
                     /locus_tag="OPY25_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462749.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCS0927391.1"
                     /translation="MKKGARMSEMLNVVTLLGSLRKGSFNGMVARTLPKVAPAGMTVS
                     PLPSIGDIPLYDADIQQEEGFPASVEALAEQIRNADGVVIVTPEYNYSVPGGLKNAID
                     WLSRLPEQPLAGKPVLIQTSSMGAIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQN
                     KVDPQTGEVVDQGTLDHLTGQLTAFGEYIQRVKA"
     gene            complement(19853..21190)
                     /gene="adeP"
                     /locus_tag="OPY25_001759"
     CDS             complement(19853..21190)
                     /gene="adeP"
                     /locus_tag="OPY25_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HCS0927392.1"
                     /translation="MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIIVTTLLG
                     WIMGDVHYNGIVSAPPSVTSVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALFVDSISSVTGAFVGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGILFLLVIFLSPLAGMVPPYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVVIVALLFVLKIVFIDAH"
     gene            21359..22024
                     /gene="yieH"
                     /locus_tag="OPY25_001760"
     CDS             21359..22024
                     /gene="yieH"
                     /locus_tag="OPY25_001760"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HCS0927393.1"
                     /translation="MSQIEAVFFDCDGTLVDSEVICSRAYVTMFRQFGITLELTEVFR
                     RFKGVKLYEIIDTISKEHGVALAKAELEPMYRAEVARLFDTELEAIAGTNTLLESIKT
                     PMCVVSNGPVSKMQHSLGKLGMLHHFPDLLFSGYDIQRWKPDPALMLHAANAMKVNVE
                     KCILVDDSSAGAQSGIAAGMEVFYFCADPHNKPIDHPNVTTFTDLAQLPGLWKARGWK
                     ITR"
     gene            complement(22119..22844)
                     /gene="phoU"
                     /locus_tag="OPY25_001761"
     CDS             complement(22119..22844)
                     /gene="phoU"
                     /locus_tag="OPY25_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCS0927394.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSELAKRVVEGDHQVNMMEVAIDEACVRIIAKRQPTASDLRLVMAIIKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTVQMLHDVLDAFARMDLDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEYIFYFVK
                     GQDFRHVGGDELDKLLAGKDPKE"
     gene            complement(22859..23632)
                     /gene="pstB"
                     /locus_tag="OPY25_001762"
     CDS             complement(22859..23632)
                     /gene="pstB"
                     /locus_tag="OPY25_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HCS0927395.1"
                     /translation="MSMVETAPSKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMYSLYPEQRAEGEILLDGDNILTNTQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(23719..24609)
                     /gene="pstA"
                     /locus_tag="OPY25_001763"
     CDS             complement(23719..24609)
                     /gene="pstA"
                     /locus_tag="OPY25_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCS0927396.1"
                     /translation="MATLDMQNTAQLAEFRRKMQARRRMKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTAGGGLANALAGSGLLILWATVLGTPLGI
                     MAGIYLAEYGRKSWLAEIIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASISGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKKKHG"
     gene            complement(24609..25568)
                     /gene="pstC"
                     /locus_tag="OPY25_001764"
     CDS             complement(24609..25568)
                     /gene="pstC"
                     /locus_tag="OPY25_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HCS0927397.1"
                     /translation="MAATKPAFNPPGKKGDMIFSALVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGFSFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFATYFQEPVGNILSNIPFVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(25704..26744)
                     /gene="pstS"
                     /locus_tag="OPY25_001765"
     CDS             complement(25704..26744)
                     /gene="pstS"
                     /locus_tag="OPY25_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCS0927398.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSAFAAASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQITANTVDFGASDAPLSDEKLNQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAITKLNPGVKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNDEWKSKVGAGSTVNWPTGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLVSADGKPVSPTEESFSNAAKGADWSKTFAQDLTNQKGDDVWP
                     ITSTTFILVHKAQKKPEQGAEVLKFFDWAYKNGAKQANDLDYASLPDNVVDQVRTAWK
                     TSIKDSNGKALY"
     gene            complement(26910..28283)
                     /locus_tag="OPY25_001766"
     CDS             complement(26910..28283)
                     /locus_tag="OPY25_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCS0927399.1"
                     /translation="MTKKIVAVTACPTGVAHAFMAAEALEIEARKRGDWIKVETRGSV
                     GAKNTLTAEEIAQADVVIIAADIELDLSGFVGKRLYRTSTGAALKKSAQEMDNAFNSA
                     EVYQGSAGRSSSAGKTELPGVYKHLMTGVSHMLPLVVAGGLCIALSFVFGIQAFNEPG
                     TLAAALFQIGGKAAFALMVPVLAGFIAFSIADRPGLAPGLIGGMLASLCGAGFLGGIV
                     AGFLAGYSVRFLAQNIKLPASMEALKPVLVLPLLSTLITGLIMIYVVGGPVSAVMEGL
                     TTFLGNMTSTNAILLGMLLGAMQGFDLGGPVNKAAYTFGVGLLASHSYMPMAAIMAAG
                     MVPALGMGVATWAARAKFTASEHEAGNASFILGLCFISEGAIPFAARDPMRVIPSTMV
                     GGAIAGGLSMYFGCTLMAPHGGLFVLAIPHAVEHVMQYLLSIALGTIVCGLMYALLKP
                     SAVAQTV"
     gene            complement(28332..29102)
                     /locus_tag="OPY25_001767"
     CDS             complement(28332..29102)
                     /locus_tag="OPY25_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate 5-dehydrogenase"
                     /protein_id="HCS0927400.1"
                     /translation="MTKRINKDTQVCMSLAARPSNFGTRFHNYLYEALDLNYLYKAFS
                     PTDLTQAISGVRGLGIRGCAISMPFKEACIPLVDELDASAKAYNTDYIAIARLLANYK
                     VSPDQVFALRGSGGMAKAVACALKDAGFTRGYIVAIDEASGKQLAELYGYEWRPDTDG
                     IEADLLINATPIGMAGGNDADKLSYSEQEVDKASVIFDVVALPPVTPLIRYARERGKT
                     VIIGSEVFAIQAVEQFVLYTGIRPDDALFQKAAAWSRL"
     gene            29197..30954
                     /locus_tag="OPY25_001768"
                     /pseudo
     CDS             29197..30954
                     /locus_tag="OPY25_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462759.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
     gene            complement(30985..32052)
                     /gene="stgD"
                     /locus_tag="OPY25_001769"
     CDS             complement(30985..32052)
                     /gene="stgD"
                     /locus_tag="OPY25_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein StgD"
                     /protein_id="HCS0927401.1"
                     /translation="MRLWTIILFSCFMVLISPVCRAGDGICHAVKGTYIYNLNLNDAR
                     IPAEKNKAGTEVRDLETLTSSESYKVGCSCLTHFSSTFREVYYTARSPLSIDTTRNGY
                     TYYTLNDNLSIATSIAVLGRGFIAVPFEAEPNVVKDGMNCYTDTVEGNLATLYTGSEV
                     KVSFLINKPFVGQVAIPGTIVANLYGGLDASSSTASTDKLAEVRIVGDIVAPQSCEID
                     SGQVIEVNFGKIPVADFSTTQGTAAAGHKVTKTVQVKCTGMLDENIVYSTFNADPVDS
                     SANMMKVLGNDDVGIMIYDKWDRMVKVTGGKMDMDMGVNNGGAETNSLTFSAAPASAT
                     GARPQPGTFEAYATITLEITN"
     gene            complement(32064..34598)
                     /locus_tag="OPY25_001770"
                     /pseudo
     CDS             complement(32064..34598)
                     /locus_tag="OPY25_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258936.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
     gene            complement(34620..35318)
                     /locus_tag="OPY25_001771"
     CDS             complement(34620..35318)
                     /locus_tag="OPY25_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HCS0927402.1"
                     /translation="MSLSMFARGIKIVILALLCLNLPSAFAGIVVGGTRVIFHGNDPD
                     STISIYNKEVDLPYLIQVWVDPFSKDDKSKPPFTVIPPVSRLEPSQEKVLRIIKTAGE
                     LPKDRESVFWFNVKNIPPSSKNKDSSTLEIAIKTRIKLFWRPASITLIPEKAVAKVKW
                     YRQGSKLVVENNSPIHMNIMDVSVDGKDVPLNMIKPFEKLTLDLPTGVTGHALAWRFI
                     NDYGAISSPVKQAL"
     gene            complement(35416..35991)
                     /locus_tag="OPY25_001772"
     CDS             complement(35416..35991)
                     /locus_tag="OPY25_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0927403.1"
                     /translation="MKLNLIASALVLSSTMLVGNAMASDGTVHFLGEVVDSTCQVTPQ
                     TADQNVNLGKVNKTAFAGVGSTAAPTEFHIDLTGCPATYTKAAVRFDGTEASNSDGDL
                     AIGNPANGDAPGDYTGDGAAITASGVAIRIYNRADNSQVKLYNDSAYSTIDTTAGTAS
                     MEFIARYIATDATVTAGTANADSQFTVEYQK"
BASE COUNT         8532 a         9852 c         9306 g         8378 t
ORIGIN      
        1 ccaggccgta cacattcata aatggcagca gccaggcatc cagcttgacc gtttcggtct
       61 tgctcttttc acgggtatga ccgacgttaa ttttaaacgc gttatctaat ggaattcccc
      121 cgttgggacc taaagccagg ccattaaagt tgatgctatc aacgttaata ttctgcccaa
      181 tattcatgta gttaatattg aggccaaatg gctcgggaag ctcatagcca cgctttcggg
      241 cttcatcacc cagaaaaggc aacactgatg tactggcagg ctttgccacc ggcgttgtcg
      301 cgactggcgg tgtggcagca gatgggacgt catcctgata gctataaacc ggcgacaggt
      361 tcgccggggg gctggtagcc gcccaggtag aaaaagccat agcgggcagc gccaacagca
      421 aaagggagcg ttttttcata atgatgaagc gtttattctg gcgagaagcg ccgccggatc
      481 gaaaggagga gggagaatat agtaatcgtc gcctggtggg cgggatttct gtgcgaatta
      541 atcttttgaa ataaaaaact attttctaca acgtctttgt tgcaacacat tagcttcatg
      601 agtggaacta tcggcccgac ggcgatcggg ccggagtgaa tcaggacaga acatgttgtt
      661 caatcgccca ggcaacacca tcttcaaggt tcgatttagt cacaaagtta gccacctctt
      721 tgaccgacgg aatggcgttg tccattgcca cgcccatacc ggcgtattcg atcatcgcaa
      781 tgtcgttttc ctgatcgcca atcgccatca cctcctctgg cttaataccc agcgcctcgg
      841 ccagtgattt tacgccggtg cctttattaa cccgtttatc gaggatttca aggaagtacg
      901 gcgcactttt cagcacggta tacttttcct tcacctctgc cggtatacgc gcaatcgctc
      961 ggtcgagaac ggcaggctca tcgatcatca taactttcag gaactgagtg ttcgggtcca
     1021 tcttctccgc ttcacaaaat accagcggaa tggtcgccac atacgactca tgcaccgtgt
     1081 agtagctgat atcgcggtta gcggtataaa gcgtatttcg atctaatgcg tggaagtgag
     1141 aacccacctc acgggatagt ttttccagat aacggtagtc atcatagctg agcgctgttt
     1201 gcgctaccgt actgccatcc cctgctttct gcaccagcgc cccgttgtag gtgatgcagt
     1261 agtcgccggg ttgttccata tgaagttctt tcagatagct gtgcacaccc gcatacggac
     1321 ggcctgtggt cagcaccacg tttacccctt tttcacgcgc agcggcaatg gcgtttttaa
     1381 ccgccggaga aatggtgtga tcgggcagca aaagggtgcc atccatgtcg atagcaatga
     1441 gtttaatagc catgaaatcc ccgcattaaa tgagtcctga ctcatgctaa cgcgattccg
     1501 ctcaaaaaac agcaaaagag tcagggataa acggggctaa agaataagac aaaccttcct
     1561 cttttgctca gtacagaagg cgagttttgt gcagtgaata ctcacattta ttagataacc
     1621 tcattaatca aacagaaaat accgtttttc taatctcatc gatattgtta ccctggtcat
     1681 gaatcaccct attgtaaaaa taaacaaaaa tgatgttaat ttaattaaag gagatcgcca
     1741 aatgtcgatg gcccttaccg ccccgcctgg caggaaaaga tttttaatcg ttgcctgtct
     1801 gtttattgga atattcattg cctatctcga ccgcgttaat gtttcggtat tagccgcaaa
     1861 cgaacccttc ttagcctata tgggtattga aggcatgcca ttgcaaattg gcatgatgat
     1921 gaccgttttt cttgccgctt atggtatcgc taatgttgta ttatcaccac ttggcgacta
     1981 ccttggtccg agaaaagcga tgatgctttg tatcctaatc tggaccatcg ccttaattat
     2041 tggcggagtt gcgacatcgt ttgcattaat tattatttgc cgcatattac tgggtatcgg
     2101 agagggtttt tattatccgc tgcaaagcgt atttattaaa aactggtttc cgaagcagga
     2161 gcgtggccgg gcaaacgcag cgtggatcgt cggccagtcg gtcgcgcccg ccattgcgat
     2221 gccttttttc acctggtgga taggcaccca cggctggcgt tccaacttct ttttatgcgc
     2281 cgctctcggg ttaatcccac tctggctact ttggcgatat gttgctgata aaccagaaca
     2341 acataaaagt atcagcgagc aggaactggc ttatatcaaa gccgggcagg aaacggaaag
     2401 cgcaagcagc agcgaaagtt ttatgttgcg ggtaaaaccg gtgattacca actattgcta
     2461 ctggttgctg gtgctgtggt acctgtgtct gcaatgcctg tactggggga tgattacctg
     2521 gctgccaacc tatcttaaat cagccagagg atttagctgg gcagaaatgg gctggctagc
     2581 gtcgctgccg tttgtcttgt cgatattttc caaagccgcc gcgggcgtct tcgtcgataa
     2641 aataggacgc agcgccccca tattaatggt gttaatgttt ttcgccggta tcagtatcta
     2701 tttcggcaca ataaccgaac acaaatatat gtcagcggta ctactctcct tcgccgtcgc
     2761 tttttgcacg atgggtacgc ctgttgcgtg gacattatta caagggatgg tgtccgggaa
     2821 atctatttcc gccgccagcg gcgtaatgaa cggcgtcgcg aacggcctgt catcattatc
     2881 accagtattt atcggtttat ttatctctat tacaggaacc tataccggcg gcttattatg
     2941 tctggttttc atcagcgcta tcgccgtggt atctgcattc gttttaacga ttaaaaaata
     3001 ttaatcacaa ggagtaaatg atgaaaatta ccagcattga tattattgat gttgctaatg
     3061 attttgcgtc cgccaccagc aaatggcgtc cggtggtggt aaaaattaat accgacgagg
     3121 gcatttccgg ttttggcgaa gtcgggttgg cctacggcgt cggcgcctcc gcaggcatcg
     3181 gcatggcaaa agatttagcc gccattatca tcggcatgga cccgatgaat aacgaagcca
     3241 tctgggaaaa gatgctcaaa aagacgttct ggggacaagg cggcggcggc atcttttccg
     3301 cagcaatgag cggtatcgat atcgcgctgt gggatatcaa aggcaaagcg tggggcgtgc
     3361 cgctgtataa aatgcttggc ggcaaaagcc gcgagaaaat cagaacctac gccagtcagt
     3421 tacagtttgg ttggggggac ggcagcgata aagatatgct gaccgagccg gagcagtatg
     3481 cacaggcggc gctgaccgcc gtcagcgaag gctatgacgc gataaaagtg gataccgtcg
     3541 caatggatcg ccacggcaac tggaaccagc aaaacctcaa cgggcctctc accgataaaa
     3601 tcctgcgtct gggctacgac cgtatggccg ccattcgcga tgcagtcggc ccggacgtgg
     3661 atatcatcgc cgaaatgcat gcctttacgg ataccacctc ggcgattcag tttggccgca
     3721 tgatagaaga gctgggcatc ttctactacg aggaaccggt catgccgtta aaccccggac
     3781 aaatgaaaca agtggctgat aaaattaata ttccactggc ggctggcgaa cgcatttact
     3841 ggcgctgggg ataccgtcct ttcctggaaa acggcagcct gagcgtgatc cagcccgata
     3901 tttgtacctg cggcggcatc accgaagtga agaaaatctg cgatatggcg catgtttatg
     3961 acaaaacggt gcaaatccac gtttgcggcg ggccgatttc cacagcagtg gcgctgcata
     4021 tggaaaccgc aatccctaac ttcgtcatcc acgaactgca ccggtatgcg ctgctggagc
     4081 cgaatacaca gacctgtaaa tacaactacc tgccgaagaa cggcatgtac gaagtctcgg
     4141 agcttcccgg catcggccag gaactgaccg aagaaaccat gaaaaaatca ccaaccatca
     4201 ccgtaaaata agccaactgt ctgcctgcgc cgcaggcaga caccctgtat ttgcgagtcg
     4261 tatcaacgcg accttatcca gcctgagata aaatcctctc agtaaagggg taacacaggt
     4321 ggcaaatgaa tttaactatc cggcaatttc gcgcgtttct ggccgtcgcg gatttgcgta
     4381 gttttaccgc cgccagcaaa tatctgtgca tcacgcaggg agctgttagc ggtttaatca
     4441 acgaaatgga aagccagatg gaggtttccc ttttcgaccg cacttcgcgc gtggtgaagc
     4501 tatcgcccga cggcgaaaag tttttacccg ccgccatgcg ggttgttgaa gagtttcaac
     4561 gggccgaaaa ttatgcccgc gacctgaaag agatcaaaaa atccctggtg cgggtggtcg
     4621 gcgcgccgct gatcgcctgt gcttttctgc cgcaaatcat ccatgccttt aagcggcagc
     4681 atccgcatac ccacgtacag cttattgata agcccatgtc gcaattacaa aaaagcatta
     4741 tgttgggaga agccgatttt ggtatcggcc cggagcggcc gctggaaccg gaaatcgaca
     4801 aacaaacgct gttcacaacg gaaatcgccc tgtactgcca tccggactat cggctgcata
     4861 aaaaaacggt gcgctgggaa gagattcaga gcgaagagct gatcgccgtt ggcaacgaat
     4921 ccgttccgat gatctccgcg accgctggcg tgcgcattaa gcccaaaatg acggtggaac
     4981 atatggcgac cgccatgtcg ctggcggcgc agtgtgaagg cgtggtgatc gccgaaacct
     5041 tttcccgcca ttacgccaaa agctatcaat tagcgacctg ttcgctcacg cctccgctgc
     5101 ggcgcaatat gaacctttat ttccatgcgt ggcgcgcgca aacgcccgcc acgcagcgct
     5161 ttaaagagtt tctattcaga tatatggatg aacatcatga tgccctggcc agccagcggc
     5221 gggccgggga ttaaggcagg ttaaatatcg atgttcgccg ctttcagggc gttctcctcg
     5281 ataaaggcac gacgcggctc aacggcatca cccatcagcg tagtgaacag ctggtcggca
     5341 gcaattgcat ctttgacggt cacgcgcagc atacggcggc tttccgggtc catggtggtt
     5401 tcccacagct gatccgggtt catttcaccc agacctttat aacgctggat agccagaccg
     5461 cgacgtgatt ctttcaccag ccactccagc gcctgctcga agctggttac cggctggcga
     5521 cgctcgccgc gttcgatgaa cgcgtcctct tcaatcagac cgcgcagctt ctcgcccagc
     5581 gtgcagatac gacgatattc cgcgccggtc acaaactcgt gatccaacgg ataatcggta
     5641 tccacgccat gcgtacgcac gcgaacgatc ggctcgaaca gattctgttc cgtattagta
     5701 tgaacatcga acttccactg actgccgtgc tgctctttct cattcagctc ggtaatcagc
     5761 gcattcaccc aacgcgttac agtctgctca tcagaaagat cggcttcggt cagagttggc
     5821 tgatacacca gctctttgag cagcgctttc gggaagcgac gctccatacg accaatcatt
     5881 ttctgcgtgg cgttatattc agagaccagt ttttctaacg cttcgccgga tagcgctggc
     5941 gcatgagcgt tcgcgtgcag agtcgcaccg tcaagcgcga tggaaatctg gtactgatcc
     6001 atcgcttcgt cgtctttgat gtactgttcc tgcttgcctt tcttcacttt gtacagcggc
     6061 ggctgggcaa tgtaaacgtg gccgcgctcg acgatttccg gcatctgacg atagaagaag
     6121 gtcaacagca gcgtacggat gtgcgagccg tcgacgtccg catcggtcat gatgatgatg
     6181 ctgtgatagc gcagcttgtc cgggttgtac tcgtcgcgac cgataccgca gcccagcgcg
     6241 gtgatcagcg tcgccacttc ctgggaggaa agcatcttgt cgaagcgcgc tttctcgacg
     6301 ttaaggattt tacctttcag cggcagaatc gcctggttct tgcggttacg cccctgcttc
     6361 gcagagccgc ccgcggagtc cccttccacc aggtacagtt cggacagcgc cgggtcgcgt
     6421 tcctgacaat ccgccagttt gcccggcaga ccggctaaat ccagcgcgcc tttacgacgg
     6481 gtcatttcac gggcgcgacg cgccgcttca cgcgcacgcg cggcgtcgat aattttgccg
     6541 acgacgattt tcgcgtcaga tgggttttcc agcaggtatt cgctcagcag ttcgttcatc
     6601 tgctgttcta ccgccgattt cacctcggaa gagaccagct tatctttggt ctgtgaggag
     6661 aatttcgggt ccggcacttt tacggaaacc accgcaatca gaccttcacg ggcatcgtcg
     6721 ccggtggcgc tgactttggc ttttttgctg tagccttctt tgtccatgta ggcgttcagc
     6781 gtgcgggtca tcgccgcacg gaagcctgcc aggtgagtac cgccgtcgcg ctgcggaatg
     6841 ttgttggtaa agcagtagat gttttcctgg aaaccatcgt tccactgcag cgctacttcc
     6901 acgccgatac cgtctttttc ggtggagaaa tagaagatat tcgggtggat cggcgtttta
     6961 ttcttgttga gatattcaac aaacgccttg atgccgcctt cgtagtggaa atgatcttct
     7021 ttgccatcgc gcttgtcgcg caggcggatg gaaacgcctg agttcaggaa tgacagttca
     7081 cgcaggcgtt tcgccaggat ctcatattca aattcagtga cgttagtgaa ggtttcgtgg
     7141 ctcggccaga aacgtaccat cgtgccggtt ttatcggtat cgccagtgac ggccaggggt
     7201 gcctgcggca cgccgtgctc gtagatctga cggtgaattt tgccatctcg ctggataacc
     7261 agctccagtt tttgcgacag agcgttgact accgagacgc ccaccccgtg cagaccaccg
     7321 gagactttat aggagttatc gtcaaattta ccgcccgcgt gcagaacggt catgatcact
     7381 tccgtcgccg agacgccttc ttccggatga atcccggtcg gaatgccacg gccatcatcc
     7441 gttacggaca cggagttatc ggcgtgaata gtcacgacga tatctttaca gtgacccgcg
     7501 agcgcttcgt cgatagcgtt atctaccacc tcgaatacca tgtggtgcag accggtgccg
     7561 tcatccgtgt cgccgatata catacccggg cgcttacgca ccgcatccag ccctttcagg
     7621 actttgatac tggaggagtc ataagaattc gacatcaacg tttctcgctc atttaatctt
     7681 gggttaatcc gttattttac ccttttccac ggtaaacatc ttcgaatttt catccgacat
     7741 gtctataacg tgttcagcgc taattgcgct gacaaagacc tgcgattgcg tggcttttaa
     7801 gcggctggcc agcagtccgc gacgcgcatc gtcaagttca gaggcaaaat catctatcag
     7861 gtacaggcag cgccgcccgc tttcgcgggt aaggaactcg ccctgcgcca gacgtaaggc
     7921 gcacatcaac aactttagct gaccgcgcga cagggtatct tccaccggcg cgccgtcagc
     7981 gcgaatgcga aagtccgctt tatgcggccc gtgcgcggtg taggtcaaca tacggtcacg
     8041 ctcaaagctt cgctccagca cgtccgcata gtctgtctct ttctcccagc cgcgctggaa
     8101 agagaacgtc agggaaaatt caggtaaaaa ctgctgacag gtatccgcca tgtcctgtgc
     8161 gatagcgcta ctgtactccg cccgccaggt actaatttgt tccgccaacg gaatcagctc
     8221 tttatcccac gggcgcaatt gctcataacg gctcacctgg cgcagcgcgg cgttacgctg
     8281 tttcagcaat cgtttcaggt tgctccaagc ggtgaagaat ccggcttcgt tgtgaaagca
     8341 tccccagtca aggaacgctc ttctgtattt ggggccgccg ttgagtaaag taaacccctc
     8401 cggcgtaatc aactgcatcg gcattaaatg cgccagctcc gcgatcttgt gaccgtcggt
     8461 accgtcgata cggactttgc tgtcgccctg cttatctttg gttaagccaa tcgacgtctc
     8521 acgctcttcg ccctgcaggc gcccgtgaag aacaaacgct tcctgctcat gacgaatcac
     8581 gcggccaggc tgcaaactgc gaaacgcccg accgtggcca agcgtataaa tagcttccag
     8641 cacgctggtt ttgccgctac cgttggcgcc aaccaggaaa ttaaagccgg gggataaagc
     8701 gagatccgca ttttctatgt tgcggaagtc tttgattagc agtctggata gcgacatatc
     8761 aactcataac cagggcgtta tcggcgcagt tagtctggtt acggccagcg cacagcaacc
     8821 ggagcgtact ggagtacgtg aggattgctc gctgcgctcg cccttcgggc cgtccataag
     8881 acgtccaaaa tacttcgtat tttgtgcgag cactgcccgg agccagaata acaagtaaga
     8941 tagcccgata ttctttacaa gcgcattggc ataacaacat aggcagccga ctgtgacgcc
     9001 gcatcctcaa tctgtacgct ggatacggaa tccgtcagca taatgcgcac ggtttcgcac
     9061 ttcagcgcat tgagcacgtc cagcacgtaa ctgacgttaa agccgatttc catctccgtc
     9121 ccgccatagc tcacgtccag aatctcttcc gcttcttcct gttccgggtt attggcggtg
     9181 attttgagct gattctcact gacgtacaga cgcacgccgc ggaatttctc attcgagagg
     9241 attgctgcgc gggcaaacgc ctgcttgagg atatcgcagc ccgcttccag atgtttatcc
     9301 ggattcttcg gcaatacgcg acggtaatcc gggaaacgac catccaccag cttcgaggta
     9361 aagataaagt cgccgacgtg cgcgcggata ttattactgc cgatctgcac gcgcagcggg
     9421 ttttcgccac cgtcgagcat acgcatcagt tcaatcacgc ctttacgcgg cacaatcacc
     9481 gagtggctag gtaaagacgc ctccagcggc attgagcaca ccgccagacg gtggccgtcg
     9541 gtcgcaacag tgcgcagttc gctaccttcc gtttcaaaca gcataccgtt taagtagtag
     9601 cgcacatcct gatgggccat cgaaaactgg gtcgcttcaa tcaggcgctt catcgtggcc
     9661 tgcggcagcg taaattcaac ttcgctttgc cagtcgtcaa gattcgggaa atcggcggca
     9721 ggcagcgtag acagcgagaa gcggctacgg ccagaacgca ccagcatccg atcgccttcc
     9781 aactgaacgg caatctccgc gccctccggc aggccgcggc agatatcaaa gaatttccgc
     9841 gccggcacgg tagtggcgcc tggctcatgc ggctgagaaa gcgtaacgcg cgcgaccatc
     9901 tccatttcaa gatcggtgcc ggtcagagaa agcgtaccgt ccgctacctg gaggagcagg
     9961 ttaccgagaa tcggcagcgt aggacgaccg cccagcgggc cgctgacctg ctgaagcggt
    10021 tttaataaat gttcacgttc aacggtaaat ttcataggat cacgacgaca atgttctgat
    10081 taaattcgaa aaatcttctt tgatatcgtg gctttcttca cgcagttgct caattttacg
    10141 acaggcatga agtacggtag tgtggtcgcg cccgccaaac gcatcgccga tttccggcag
    10201 actgtggttg gtgagctctt ttgccagcgc catagccatc tggcgcggac gtgctaccga
    10261 gcgagatcga cgcttagaaa gcagatccgc aattttgatt ttgtaatact cggccaccgt
    10321 cttctgaata ttgtcgatgg tgaccagttt ttcctgcaac gccagtaaat cgcgcagcgc
    10381 ttcgcgcaca aagtcgatag taatcgcccg gccggtaaag ttggcattgg cgatcacccg
    10441 gttcagcgcg ccttccagtt cacgtacgtt agagcgtaga cgcttggcga taaagaacgc
    10501 tacttcgcct ggcagacgaa tatcattttc gtccgctttt ttcatcagga tcgccacgcg
    10561 ggtttccagc tctggtggtt cgatcgccac tgtcagcccc caaccaaagc gggacttgag
    10621 acgatcctca acgccgttga tctctttcgg atagcgatcc gacgtcaaaa tgatctgctg
    10681 attgccttcc agcagagcgt taaaggtgtg gaaaaactct tcctgggatc gttctttatt
    10741 ggcgaagaat tgaatatcgt cgatcagcaa tgcgtcaacg gagcggtagt agcgtttaaa
    10801 ctcttcgatg gcgttatttt gcagggcttt taccatgtcc tgcacaaagc gctcggagtg
    10861 catatacacg actttcgcgt tgggtttgcg cgccataatg ccgttaccca ccgcgtgcag
    10921 caggtgagtt ttacccagac cggtgccgcc atagaggaat aacgggttat aggcgccgcc
    10981 aggattatcc gccacctgac gtgccgccgc gcgcgccagt tggttggatt taccttcgac
    11041 gaagttatca aatgtatgct taacattgac gttggagcgg taggtcggct ccgccggcgc
    11101 tggtacgtta tcccagcccg aacgggccgc gggcgctacg cgctgcggtt gcgccgtcgt
    11161 tgtctgcgta ggcgcgacaa cgttatgcac aggcgttttt agcgtttgcg taacgggctt
    11221 tgttcccact tcaaaacgca gttgtggggc atccgcgccg cagaatgtgt tgagtaatcc
    11281 attgatattg ttgaggtact tatctcttac ccaatcgagc acaaaacggt ttggcgcata
    11341 caaagccagc gtgttatcgc tcagttccgc ctgcaacggg cgtatccaca tactgaattc
    11401 tgtggctggt aactcatcct gcaatcgggc aagacactgc tgccaaagcg aaagtgacac
    11461 ggcggactcc actcgaacaa aagtcgataa atgacaaagg ctgatacatt aatgattgtt
    11521 ggcgcacgtc gataagaccc tgcatgaagg gtgacgcact aaccgctgtc tgcggttttc
    11581 acggatcttt caaacgatcg cgacttcacg cagtctgaaa gatttcgtgt tcatgcctga
    11641 ccaggatcgt ttgaaacgat caggaccgcg gatcatagcc taaactgagc aagagatctt
    11701 ctgtttctca cagattcttc ccgatttatc cacagggctt tccaggaaag gataagtgta
    11761 atcgatccag gggaactcct gtacgctttc gcgcgcatat tgaaaaaatt aatatgtaaa
    11821 ggtgagcaga cgcctaaaag atcgcataaa gatccagggc gatccttgcg ctttacctgg
    11881 cagtccgtat aattctccac ccgtcgcgca atgcccgtca tatggcgtca acgctgctta
    11941 ttttccgcac aaaaaggcgt ggaaaatcgc gggaaagtaa ggaaagagaa ttgactccgg
    12001 agtgtacaat tattacaatc cggcctcttt aatcacccac actgtggcgt aagtcgttca
    12061 aagtttgttc gggtatacgc aaaagtcagt gaatttattc aagtttaggt agaaatcgcc
    12121 atgaaacgca cttttcaacc gtctgtactg aagcgcaacc gttctcacgg cttccgtgct
    12181 cgtatggcta ctaaaaatgg tcgtcaggtt ctggcacgtc gtcgtgctaa aggccgcgct
    12241 cgtctgaccg tttccaagta ataaagctaa cccctgagtg gttaagctcg catttcccag
    12301 ggagttacgt ttgttaactc ccgctcattt cacattcgtc ttccagcaac ctcaacgggc
    12361 tggcacgccg caaatcacca tcctcggccg cctgaattcg ctggggcatc cccgtatcgg
    12421 tcttaccgtc gccaagaaaa atgttcgacg tgcgcatgaa cgcaaccgga ttaaacgtct
    12481 gacgcgtgaa agcttccgtc tgcgccagca tgaacttcct gcaatggatt tcgtggtggt
    12541 ggcgaaaaaa ggggttgccg acctcgataa ccgtgctctc tcggaagcgt tggaaaaatt
    12601 atggcgccgc cactgtcgcc tggctcgcgg gtcctgatag cccttattcg ggtctatcaa
    12661 cgcctgatca gtccgctgct tgggccgcat tgtcgtttca cgccaacgtg ctcaagctac
    12721 ggaattgagg cattgcgcag gtttggagtg ataaaaggca gttggttgac ggtgaaacgc
    12781 gtattaaaat gccacccttt acaccctggt ggtgacgatc ccgtcccgcc cggaccattt
    12841 gataccagag aacactaacg atggattcgc aacgcaatct tttagtcatc gctttgctgt
    12901 tcgtgtcttt catgatctgg caagcctggg agcaggataa aaatccgcaa cctcagactc
    12961 aacagaccat gcagacaacg accaccgcag cgggtagcgc cgccgaccag ggcgtaccag
    13021 ccagtggcca ggggaaaatg attacggtga aaaccgatgt gcttgatttg actatcaaca
    13081 cccgtggtgg tgatgtcgag caggccttgc tcccggctta cccgaaagaa ctgggttcca
    13141 acgaaccgtt ccagctgctg gaaaccaccc cgcagtttat ctatcaggcg caaagcggcc
    13201 tgacaggccg cgacggcccg gataacccgg cgaacggccc gcgtccgctg tacaacgtcg
    13261 agaaagatgc gtttgtactg gccgacggtc agaacgaact gcaggttccg atgacttata
    13321 ctgacgccgc aggcaacacg tttaccaaaa cgtttgtctt taagcgtggc gattatgcgg
    13381 ttaacgtgaa ctatagcgtg cagaacaccg gcgaaaaacc gctggaagtc tccacctttg
    13441 gtcagttaaa acaatccgtc aacctgcctc ctcatcgcga caccggcagt agcaactttg
    13501 cgttgcatac gttccgcggc gcagcgtact ccacgccgga tgagaagtat gagaaataca
    13561 aattcgacac cattgccgat aacgaaaacc tcaacgtcag ctccaaaggc ggttgggtgg
    13621 caatgttgca gcagtatttc gctaccgcat ggattccgcg taacgacggc accaacaatt
    13681 tctacaccgc caatctgggt aacggcattg tcgctatcgg ctataaagcg cagccggtac
    13741 tggtacagcc aggccagact ggcgcgatga ccagcaccct gtgggtcggc ccggaaattc
    13801 aggataaaat ggcggctgtt gcaccgcacc tggatttgac cgtggactac ggctggttgt
    13861 ggttcatctc tcagccgctg ttcaagttgc tgaagtggat ccacagcttt gtgggcaact
    13921 ggggcttctc cattatcatc attaccttta tcgttcgcgg tatcatgtac ccgctgacca
    13981 aagcgcagta cacgtcaatg gcgaagatgc gtatgctgca gccgaaaatt caggcgatgc
    14041 gcgaacgtct tggcgatgat aaacagcgcc aaagccagga gatgatggcc ctgtacaaag
    14101 cggagaaggt taacccgctg ggcggctgct tcccgctgat catccagatg cctatcttcc
    14161 tggcgttgta ctacatgctg atgggttcca ttgaactgcg tcatgcgccg ttcgcgctgt
    14221 ggattcatga cctgtctgca caggacccgt actacattct gccgatcctg atgggcgtaa
    14281 cgatgttctt cattcagaag atgtcgccga ccaccgtgac cgacccgatg cagcagaaga
    14341 tcatgacctt tatgccggtc atctttacag tgttcttcct gtggttcccg tcaggtctgg
    14401 tgctgtacta tatcgtcagc aacctggtca ccatcattca gcagcagctg atttaccgtg
    14461 gtctggagaa gcgtggcctg catagccgcg agaagaaaaa atcctgattc ggtgtaggcc
    14521 ggataaggcg aagccgccat ccggcaaggc gcgccggtca gcctgatggc gctaacgctt
    14581 atcaggccta caatcaaaag gcggtcatat gaccgccttt ttttattgca acaaagttga
    14641 gactaaccat gagccataac gacactatcg tcgcccaggc aaccccaccg ggacgcggtg
    14701 gcgtgggtat cctgcgtatt tccggtctga aggcgcgcga cgttgcgcaa gaggtgctgg
    14761 gcaagctgcc gaagccgcgc tatgccgact acctgccgtt taaagatgtt gacggcagcg
    14821 cgctggatca gggtattgcg ctgtggttcc ccggcccgaa ctccttcacc ggtgaagatg
    14881 tgctggagct acaagggcac ggcggtccgg tgattctgga cctgctgtta aaacgtatcc
    14941 tgacgcttcc aggcgtgcga attgcccgac cgggcgagtt ctccgagcga gcgttcctca
    15001 acgataagct cgatttagcc caggcggaag ccattgccga cctgatcgat gccagttccg
    15061 aacaggcggc gcgttcggcg ctaaactcgt tacagggggc attttccgcc cgcgttaacc
    15121 accttgtgga agcacttact cacctgcgaa tctacgtcga agcggctatt gattttccgg
    15181 atgaggagat cgactttctc tctgacggca aaatcgaagc gcagctcaat ggcgtcatcg
    15241 ccgatcttga cgccgtgcgc accgaagcgc gccagggcag cctgctgcgc gaagggatga
    15301 aggtagtgat tgccggacgc ccgaatgccg ggaaatccag cctgctgaat gcgctggcag
    15361 gccgtgaagc ggccattgtc accgatatcg ccggtaccac gcgcgacgtg ttgcgcgagc
    15421 acatccacat cgacgggatg ccgctgcata tcatcgatac cgccggactg cgcgacgcca
    15481 acgacgaagt tgagcgtatc ggcatcgaac gcgcctggca ggagattgaa caggccgatc
    15541 gagtgctgtt tatggtggat ggcaccacga cggacgccgt tgaccctgcc gacatctggc
    15601 cggactttat cgcccgtctg cccaaaaatc taccgattac cgtggtacgt aacaaggcgg
    15661 atatcaccgg cgaaacgctg ggtattagtg aagtaaacgg tcactcactg gttcgcctct
    15721 cggcgcgtac cggcgaaggc gtcgacgtgt tgcgtaacca cctcaagcag agcatggggt
    15781 ttgataccaa tatggaaggc ggcttcctgg cccgccgccg tcacctgcag gcgctggcgg
    15841 aagccgctaa ccatcttgaa cagggcaaag cgcagctatt aggcgcatgg gcgggggaac
    15901 tgctggcgga agagttgcgc ctggcgcagc aaagcttaag cgagattacc ggcgagttta
    15961 cctccgacga cctgctggga cggattttct ccagcttctg tatcggtaaa taacgttgtg
    16021 ttgcccggtg gcgcgatgct taccgggcct acaaaacccg taagccggat aaggcgttta
    16081 cgccgccatc cggcagcaat gatttcccat gcggaaatca ctgttgtcca aatgacaact
    16141 cgtctcgcgc aacgtcgccc cgtattctta gcgccacact tttcgtgagg ccgctatgaa
    16201 acgttttcta ctgtgtagtt ttgccctggt tttactctat cctgctggta ttgatatgta
    16261 tctggtcggt ttaccgcgta tagccgccga tctgaacgcc agcgaggcgc agttgcatat
    16321 cgccttctcc gtttacctgg ccggaatggc gacggccatg ctgtttgccg ggaagatagc
    16381 cgaccagtca ggccgcaagc cggtcgcgat cgtcggcgcg atcgtcttta tgatggcctc
    16441 actgctttgt tcacgggcgt cggaaggctc gctatttctg agtgggcgtt ttcttcaggg
    16501 ggtaggagca ggcggctgct atgtggtggc gttcgccatt ctgcgcgaca cgctcgacga
    16561 gcatcgccgg gcgaaagtgc tgtcattatt gaatgggatt acctgtattg tgccggtact
    16621 cgccccggtg atggggcatt tgattatgct tcgtttcccc tggcaaagtc tgttctatac
    16681 gatgtccacg atgggcatta tggtgggcct gttatcactg tttatcctgc gcgagacgcg
    16741 cccggcaagg ctggctccac gcgatttatc accatcgtcg tccgccgccg agtcgctggt
    16801 taaccgtttt ttcgttagtc gactagcgat caccaccctt agcgtgtcgg tgatcctgac
    16861 cttcgtcaat gcctctccag tgctgctgat ggaggtgatg ggatttagcc gtggcgacta
    16921 tgccattacc atggcgctca ccgcaggcgt cagcatggtc gtctcttttt ctaccccttt
    16981 tgcgcttggg ttatttaagc cgcgaacctt aatgctcgtc tcacaggggc tgtttttgac
    17041 ggctggcgtg acgttaagcc ttgctcatac caataccgtc acgctctttg gcctgacgct
    17101 tatctgcgcc ggattctcgg ttggttttgg cgtcgcgatg agccaggcgc tggggccgtt
    17161 ttcgctgcgc gccggagtgg ccagttccac gctgggtatc gctcaggttt gcggttcatc
    17221 actgtggatt tggctggcgg caatactcgg tatcagcgcg atgaatatgc tgatcgggat
    17281 tctgattggt tgtagcatag tgagtattct gctgatcttc tccgtcgcgc ccaacaggtc
    17341 cgtagccgag catgaagaaa tcccttacca gtctcgatct taatctgctg ttatgcctac
    17401 agttactcat gcaggagcgc agcgtcacta aagctgcaaa acggatgaac gtaacgccct
    17461 ctgcggtcag caaatcgctg gcgaaactcc gggcatggtt tgacgatccg ctgttcgtca
    17521 atacgccgct gggcctggcg ccgacgccgc tgatggtcag tatggagcaa agtctggcgg
    17581 actggatgca gatggggaat caactgcttg ataagccaca tcatcaaacg ccgcgcggtt
    17641 taaaatttga gttggcggca gagtcgccgc tgatgatgat tatgtttaat tcactgtcgc
    17701 agcagattta tcagcgctat ccgcaggcta ccattaaggt tcgcaactgg gattatgact
    17761 cgctggaggc gattacgcgc gggaaagtcg atatcggatt taccggacgc gaaagccatc
    17821 cccgctcgcg agagttgatc agtctgttgc cgctcgcgat tgactttgag gtactgttta
    17881 gcgatttacc gtgggtctgg ctgcaggaag atcatccggc actgcgcgaa gcgtgggatc
    17941 tggacacttt tctgcgctac ccgcatatca gtatttgctg ggagcaaagc gatacctggg
    18001 cgctggatga tgtcctacaa gaaatgggac gcaaacgcca tatcgcgtta agcctgccgg
    18061 ggttcgagca gtcgctcttt atggccgccc agccgggtca caccctgata gcaaccgcgc
    18121 cgcgctattg ccagcactac aatcagctcc accagctacc gttagtggcg cgccccctgc
    18181 cttttgatgc gcaacagcgg gaaaagctga tggtgccgtt taccctatta tggcacaaac
    18241 gtaatagtca taatcccaag attgtgtggc tacgacaggc tatcaacacg ctctgccgtc
    18301 gccttatctg accacctgcg ttgataaatt aaccttactc ttaccagaaa tgtcaccgtc
    18361 tgattaaaga accttctgaa attgaatttt tagcgcgtaa aacctgtcca taatttacgt
    18421 taatgttact ctcgtcatta tcacggccca ttaatcacgg agcgaaaaat ggcgactcac
    18481 tttgccagag ggatacttac ggagggacag ttggtttcaa ttcgtctctc ttcgtcttgc
    18541 catattgaag ccagaaacct gcctgctcac cgacgaacgc gttttctcgc ctccagaggc
    18601 cttcttgccg aactgatgtt tatgctgtac ggaattagcg agctgccgga aatcattatt
    18661 caggcgaaag gtaaacccgc gtttcgtgac aaaaatctgc caggtttttc tatctcctac
    18721 gccggaaata tggttggcgt ggcgttgacc accgaaggag agtgcgggct ggatatggaa
    18781 ttacagcgca cctcccgcgg ctttcaccat ccgcattcgc tcgaacgcca ccctttctcc
    18841 cgtaatgaaa acttatgggt agccaatcaa aacgatccca acgaagcgcg agcgcaactc
    18901 attacattgc gccagagcgt gttaaaactc accggcgatg tcatgaatga cgatccgcgg
    18961 gagctgcaac ttttacccgt tgccggacgc ctgaagtgcg cgcatgtcac gcagcttgaa
    19021 gccgtgtgcg atgcggaaga tgtgctggta tggtccgtaa ccgttacgcc agcgatagaa
    19081 aaattaaaag tgtgggagtt cgatggcaaa ctgggctgga aaagcctgcc cgatatccag
    19141 acgcgcgcca atgagccaac cggccgtctg atgcgattcg cccaactccc cgccgccaaa
    19201 tcgtatacgc ttaatcgttc ataatgaaaa aaggggcacg tatgtctgaa atgctgaatg
    19261 tggttacatt gctgggaagt ttacgcaaag gttcctttaa cgggatggtg gcgcgtacgc
    19321 tgcctaaagt cgcgccggca ggaatgacgg tatcgccgct gccttcaatc ggggatattc
    19381 cgctgtatga cgccgatatc cagcaggaag agggatttcc agccagcgta gaggcgctgg
    19441 cggagcagat tcgcaacgcc gacggcgtcg tcattgtgac gccggaatat aactattccg
    19501 ttcccggcgg cctgaaaaat gccatcgact ggctatcccg tctgcctgag cagccgctgg
    19561 cgggtaagcc cgttcttatc cagaccagct caatgggagc gattggcggc gcgcgctgcc
    19621 agtatcatct gcgccagatt ctggtgttcc ttgatgcgat ggtgatgaat aaaccggaat
    19681 ttatgggcgg cgtgattcag aataaagtcg acccgcagac tggagaagtg gtggatcagg
    19741 gaacgttaga tcatttgacc ggtcagttga ccgcatttgg cgagtatatt cagcgcgtta
    19801 aagcgtaagt tagttaaaca ccctcccccc gatggggcga gggttcattt catcagtgtg
    19861 cgtcaataaa cacaatcttc agcacgaata acagcgcgac aatcactacg cacgggctaa
    19921 ggtcgcgcag gcgaccggta ccgattttca tcacgcagta agagataaag cccagcgcga
    19981 taccttcggt gatcgagaag ctaaacggca tcattaccgc cgtaataaac gccgggaccg
    20041 attcggttaa atcctgccag tttacccgcg ccaggctgga ggtcatcagc acgccgacgt
    20101 aaatcaacgc gcccgccgcc gcgtaaggcg gcaccatgcc cgccagcggc gacaggaaga
    20161 taaccagcag gaacaaaata ccgactacca ccgccgtcaa accggtgcga ccgcccaccg
    20221 aaacgccgga agacgattca atataagcgg tcacagaaga ggttccgaca aatgcgccag
    20281 tgacggaaga gatactatca acaaacagcg cctgcttcat gcgcgggaat ttgcctttct
    20341 catccgccag gccggcttta tcggtcacgc caatcagcgt accggaggag tcaaacaggt
    20401 ttaccagcat gaaggagaaa ataacccccg ccaggccaag attgaacgag cctgccaaat
    20461 cgacatgccc taccacgctg gtgacgcttg gcggcgcgga gacaatgccg ttgtagtgca
    20521 catcgcccat tatccagcca agcagcgtcg tgacgatgat ggacaccagc accgccgcat
    20581 gaatgttgcg cgaagcgaga atcgcaataa taaagaatcc gagaaccccc agcagcacgc
    20641 tgtgcgaagt caggttgccg atgctgacca gcgtttccgg gttagcgacg atcacgccgg
    20701 cgtttttcag ccccatcatg ccgataaaca ggccgatgcc gctggtgatg cccacgcgca
    20761 ggctgaccgg aatgttggca atcatccagt aacgcacgcg gaagatagtc agcaataaaa
    20821 gaccaacagc gccccagaaa atggcgccca tgcctacctg ccacggcagt cccattgcct
    20881 gcacaaccac gaaggcaaag aacgcattca gccccatcgc gggcgccagc gccaccggca
    20941 ggttagcgaa caggcccatc agaatactgc caaaggccgc aatcagacag gtggtcacaa
    21001 agacggcgct ggtgtccatg ccagctacgc ccagaatttg cgggttaaca aaaacgatat
    21061 aaaccatcgt caggaaagtg gtaaaaccgg cgatcacttc ggttcgtgcc gtcgtgccat
    21121 gttcgcgcag tttaaacacg cgttccagca taccctgacc agaagcctgg gtggtgtgtt
    21181 gttgactcat tatcaatttc cggagaaagg agggaaaatt cgccgttatc ctataccaaa
    21241 atgcgacacc tggcgcagtt gtgtggtaat ttttttcact caatttgtta gtacggcaac
    21301 gattgcgtcc cctcattcag cattacgtaa acgttaaact tgttaaaatg gaaatgacat
    21361 gtcccaaatc gaagcggtgt tttttgactg tgacggcacg ctggtcgaca gtgaagtaat
    21421 ttgctcgcgc gcctatgtca ctatgttccg gcagttcggc attacgcttg agctcacgga
    21481 agtattcaga cgctttaaag gcgtaaagct ctacgaaatt atcgatacca tcagtaaaga
    21541 gcatggcgtt gcgctggcaa aggcggagct ggagccgatg tatcgcgcgg aagtggcgcg
    21601 cctgttcgat accgaactgg aagcgatcgc gggcacaaat accctgctgg agagcattaa
    21661 gacgcccatg tgcgtggtat ccaacgggcc ggtcagtaag atgcagcatt cgctgggtaa
    21721 actgggcatg ttgcatcatt ttcccgattt gctgtttagc ggttacgata ttcaacgctg
    21781 gaagcccgat ccggcgctga tgctccatgc ggcgaacgcc atgaaggtca atgttgagaa
    21841 gtgtattctg gtggatgatt ccagcgcagg cgcgcagtca ggaattgcgg cgggaatgga
    21901 agtattttat ttctgcgccg atccgcataa caagccgatc gatcacccta acgtgacgac
    21961 atttaccgat ttggcgcagt tgccgggatt gtggaaagcg cgcgggtgga agattacgcg
    22021 ttaactgaaa tgccggatgg cgctaacgct catccggcct acagcatctg tacctgtagg
    22081 cccggtaagc gcagcgccac cgggcaaaag aatgagattt actctttcgg atctttcccc
    22141 gccagcagct tatccagctc atcgccgccg acgtgacgga aatcctgccc cttcacgaag
    22201 tagaagatgt attcgcagat attctggcaa cggtcaccga tacgctcgat agaacgagcg
    22261 cagaataacg cggtcagcac gctgggaatg gtgcgcgagt cttccatcat gtaggtcatc
    22321 agctgacgca cgataccttc gtactcctgg tcaactttct tgtcttcacg gtagatacgc
    22381 accgcttcgt cgagatccat gcgcgcgaac gcatccagca cgtcgtgtag catctgcacg
    22441 gtgtggcggc ccagcgactc cagactcacc aacagcggct ggtgctgctg ggagaatttc
    22501 tccagcgcgg tacggcagat tttatccgcc acgtcgccaa tgcgctccag ttcggcgatg
    22561 gttttgataa tcgccatcac cagacgcagg tcactcgccg tcggctggcg cttggcgata
    22621 atacgcacgc aggcttcatc gatggcgact tccatcatat taacctgatg gtcgccttct
    22681 accacgcgct tcgccagctc gctgtcctgg ttgtgcatgg cggtaatagc gtcagaaagc
    22741 tgctgctcca ccatgccgcc catggtcatt acctgagtgc ggatgctttc cagttcggcg
    22801 ttgaactggc cggaaatatg tttattaagg ttcagactgt ccattacgca ctcctgaatt
    22861 aaccgtaacg accggtgata taatcttctg tttgtttctt cgcgggcttg gtgaacagat
    22921 cgtccgtgtt gctgaactca atcaactcgc ccaggtacat aaacgccgta tgatcggaac
    22981 aacgtgccgc ctgctgcatg ttatgggtca cgatcaccac ggtgtaatcc tgtttcagct
    23041 cggtgatcag ctcttcgata cgcccggtgg agatcgggtc cagagctgaa catggctcat
    23101 ccagcagcaa cacttccggg cgaatggcga taccgcgcgc aatgcacaga cgctgctgct
    23161 gaccaccgga gagagagtac ccgctctggt gcaatttatc tttggtttcg ttccataatg
    23221 cggctttggt caacgcccac tgcacgcgct cgtccatatc ggcacgagac agcttctcaa
    23281 acagacgcac gccaaaggcg atattgtcat agatggacat cgggaacggc gtcggcttct
    23341 ggaataccat ccccactttt gcgcgcagca gcgcgatatc ctgggtgttg gtgagaatat
    23401 tgtcgccatc cagcagaatt tcaccttccg cgcgctgctc cggataaagc gagtacattt
    23461 tattgaaggt acgcagtagc gttgatttac cgcagccgga tggcccgata aatgccgtta
    23521 cctgattctt cgcgatatcc agattaatgt tcttcagggc atggaatttg ccgtagtaga
    23581 agttcaaatc acgaacctga atcttactcg gggcagtttc aaccatactc atttcactct
    23641 tttcctcatc cagcgccgca tccgccacgc cgtaaaataa tgcctgatgg cgctacgctt
    23701 atcaggccta caatgtcttt aaccgtgttt tttcttcgcg aaaacaacac gcgccagaat
    23761 attcagcagc agtacgcaca gggtaataat cagcacgccc gcccaggcta attgttgcca
    23821 ttcggcaaac gggctcatcg cgaatttaaa aatggtcacc ggcaggttgg cgatcggctg
    23881 catcatgtcg gtgctccaga actggttcga gagcgcggta aacaacaatg gcgccgtttc
    23941 cccggcgata cgcgcaatag ccagcagaat accggtcata atcccggaga tagaggcttt
    24001 cagcgtaatc gcggagatca tcttccactt cggcgtaccc agcgcataag cggcttcacg
    24061 caggctatcc ggtaccagct tgagcatgtt ttcagtggta cggataacga tcggcacctg
    24121 caacagcgcc agcgcaatca cccctgccca gccggagaag tgctgcatct gcgccaccac
    24181 gatggtgtaa acaaacagcc ccacaacaat tgacggcgcg gaaagcagaa tgtcgttaat
    24241 aaagcgaatg atttccgcca gccaggattt acggccatac tcggccaggt aaatacccgc
    24301 cataatcccc agcggcgtac ccaatacggt agcccagaga atcaataatc cactccccgc
    24361 cagggcgttc gccagcccgc cgcccgccgt gttcggcggc ggcgtcattt cggtaaacag
    24421 cgccagcgac ataccatcaa tgccgcgcgt gatggtggac atcaaaatcc agatcagcca
    24481 gaacaggcca aatgccatcg tcgccattga gagcgttagt gcgatacggt tcttcatgcg
    24541 gcgacgcgcc tgcatcttgc gacggaattc cgcgagctgc gcggtgttct gcatatcaag
    24601 cgtagccatt aacgtgctcc ctcgttcttc gccagacgca taatcatgaa cttagacgcc
    24661 gccaggacga taaaggtgat cacaaacagg atcagcccca gctccatcaa cgctgccacg
    24721 tgcagacccg attccgcctc agcgaattcg ttggccagcg cggaagtgat gctgttgccc
    24781 ggcatataca gcgacgcgct gtcgagctgg taggtgttgc cgatgataaa agtgaccgcc
    24841 atcgtttcac ccagagcacg gcccagcccc agcataatgc cgccgatcac gccatttttg
    24901 gtgaacggta gcacgatgcg ccagataact tcccaggtag tacagccgat accgtaagcg
    24961 gactctttca tcattaccgg cgtttgctcg aagacgtcgc gcataaccgc cgcaatgtag
    25021 gggatgatca tgatggcgag gatgacgccc gccgccagaa taccgatacc aaaggccggg
    25081 ccggagaaca gcgcgccgac aaacggaatg ttggaaagaa tattgccgac cggctcctgg
    25141 aagtacgtcg caaacagcgg cgcgaagata aacagccccc acatgccgta cacgatactg
    25201 ggaattgccg ccagcagttc aatggcgatg ccgagcggac gcttcagcca gcctggcgcc
    25261 agctcggtta aaaacagggc aatgccgaaa ctaaccggaa cggcgatcag cagtgcgata
    25321 aaggaggtta ccagcgtgcc gtaaatgggc accagtgcgc cgtagatatc gtttggcgcg
    25381 tcccactcct tagtccaaag aaatgagaaa ccaaatttct gaatacttgg ccaggaggag
    25441 atgatcaatg agacgataat accgcccaac atcaatagca caatcagcgc agccagtttt
    25501 accagcgcgc tgaaaatcat gtcgcctttt ttacccggcg ggttaaaagc aggcttggtt
    25561 gcagccataa attactcttt ccattaaacg cattttacga cgttgcccct gccggatggc
    25621 gctacgatta tccggcctac aacgtgggcc tgcggtcgaa accgtagggc ggataatcgt
    25681 agcgccatcc gccaattcgt taattaatac agcgccttac cgttgctgtc ttttatactg
    25741 gtcttccagg cggtacgaac ctgatcaaca acgttatccg gcaggctggc gtagtccaga
    25801 tcattcgcct gtttagcgcc atttttgtag gcccagtcga agaacttcaa cacttcagca
    25861 ccctgctcag gtttcttttg cgctttgtgg accaggataa aggtggtgga ggtgattggc
    25921 cacacatcgt cacctttctg gttggtcaga tcctgcgcga aggttttgct ccagtctgcg
    25981 cctttcgccg cattagagaa gctctcttcc gtcgggctta ccggtttgcc gtcggcagaa
    26041 accagtttgg tgtaggccag gttgttctgt ttagcgtaag cgtattcaac gtagccgata
    26101 gcgcctggca gacgctgtac aaatgccgcg atgccgtcgt tacctttacc gcccagaccg
    26161 gttggccagt tcacggtaga acccgcgccc actttcgatt tccactcgtc gttgactttc
    26221 gccaggtaac tggtgaacac gaaggaggta ccggaaccgt cagcgcgacg caccacagcg
    26281 atattctgtg agggcagctt cacgcctggg ttcagtttgg tgatggcttc atcatcccac
    26341 ttcttgattt taccgaggta gatgtcaccc agcgttttac catccagcac cagttcgccg
    26401 gatttgaggc ctggaatatt caccgccagc accacgccgc cgatcaccgt cggaaactgg
    26461 aacaggcctt cctgattcag tttttcgtca gacagcggcg catcggaagc gccaaaatca
    26521 acggtattcg cggtaatttg tttcacgccg ccggaagagc ctatcccctg gtaattgact
    26581 ttgttaccgg tttctttctg gtaggtatcc gcccatttgg catacaccgg cgcaggaaac
    26641 gttgcaccgg cacctgtcag gcttgctgct gcaaaggcag agaacgcgct catcgataag
    26701 gtcgcggcga caacagttgc gacagtggta cgcataactt tcataatgtc tcctgcacgg
    26761 tttcggtaaa tcgttgtttg agttgctacg atgagcaaaa taggacaaat tgatgacagt
    26821 tatatgtctt gattatgacg gtttgatgac aatggaaata aaaaagctgg cccggggaga
    26881 caccagacca gcctgcaggg ggagatgaat taaactgttt gcgcaaccgc agacggtttc
    26941 aacagcgcgt acatcaggcc gcagacaatc gtgcccaggg caatcgagag caggtactgc
    27001 atcacatgtt ctaccgcatg cgggatcgcc aggacaaaga gaccaccgtg tggcgccatc
    27061 agtgtacaac cgaaatacat ggacagtccc ccggcgattg cgccaccgac catcgtggaa
    27121 gggatgacgc gcatcgggtc acgcgcagcg aagggaatcg ccccttcaga gataaagcac
    27181 agccccagga taaaggatgc gttacccgct tcatgctcag aggcagtgaa tttcgctctg
    27241 gccgcccagg ttgcgacgcc catccctaat gccggtacca tccctgccgc cataatggcc
    27301 gccatcggca tataggaatg agaagccagt aaaccgacgc cgaaggtata cgcagcttta
    27361 ttcaccggcc caccaaggtc aaaaccttgc attgcgccca gcaacattcc cagcaagata
    27421 gcattcgtag aggtcatatt ccccaggaac gtcgtcagcc cttccatcac cgcagaaacg
    27481 gggccaccca ccacgtaaat catgattagg ccggtaatca gcgtagacag tagcggcaga
    27541 accagtaccg gcttaagcgc ttccattgac gctggcagct taatattttg cgccagaaac
    27601 cgtacgctgt aaccggccag aaaaccggcc acaatccctc ccaggaaacc agcaccgcac
    27661 aggctggcca acatcccgcc aataagcccc ggggccagac ccggacgatc ggcaattgag
    27721 aaggcaataa acccagccag taccggcacc atcagcgcaa aggccgcctt accaccgatt
    27781 tgaaataacg cagccgccag cgtgcccggc tcattgaagg cctggatacc gaagacaaaa
    27841 gagagcgcga tacataaccc tcccgccacc accaaaggaa gcatatggga tacgccggtc
    27901 attaaatgct tataaacgcc gggtagctct gttttaccag ctgaagaaga gcgcccggca
    27961 ctcccctgat agacctcggc gctattgaaa gcattatcca tttcctgcgc actctttttt
    28021 agcgccgcgc cggtactggt gcgatagagt cttttgccaa caaagcctga cagatccagc
    28081 tcaatatccg ccgcgataat caccacatcc gcttgcgcta tctcttccgc ggtcagcgtg
    28141 ttcttcgccc cgacggaacc gcgggtttca accttgatcc agtcaccacg cttgcgggct
    28201 tcaatttcca gcgcttcggc agccataaag gcatgggcga cgcccgtcgg acaggccgtc
    28261 acagcaacaa tttttttagt catagtagga taccctgttc ttttaattta aagaaaaagc
    28321 gggaaaaaat gttacagacg tgaccaggcc gcggctttct ggaacagtgc gtcatccggg
    28381 cgaatcccgg tataaaggac aaattgctcc acggcctgaa tagcaaacac ttcggaaccg
    28441 ataatcacgg ttttaccgcg ttcacgggcg tagcggatta gcggcgtgac gggcggtagc
    28501 gccaccacat caaagataac gctcgcctta tccacttctt gttcggaata agagagtttg
    28561 tcggcatcat taccgccagc cattccgata ggcgtggcgt taattaacaa atcggcttca
    28621 ataccgtcgg tatccgggcg ccattcatag ccatagagtt cggccagttg tttacctgac
    28681 gcttcatcaa tcgcgacaat ataaccacgg gtaaaccccg catccttcag cgcgcaggcc
    28741 accgcctttg ccataccacc gctgccacgc aaagcaaaca cctggtcggg agagaccttg
    28801 taattcgcca gcaagcgagc tattgcaatg taatcggtgt tgtacgcctt agcggaagca
    28861 tccagttcat ccaccagcgg aatgcaggct tccttaaatg gcatagagat cgcgcaccca
    28921 cgtatcccca gcccgcgcac gccgctaatg gcctgcgtaa gatcggtcgg cgagaaagct
    28981 ttgtagagat aattgagatc cagcgcttcg tacagatagt tgtgaaagcg tgtaccgaag
    29041 ttacttgggc gtgcagccag ggacatgcag acctgagtgt ctttattaat gcgctttgtc
    29101 atgatgaatc ctcatagaag ttgcgataga gaaaatcatc ggctaaaaag gggatattaa
    29161 aaattgctca ttcccgttcg ggaaatttca tcttttatgg caacccggca cactgaacaa
    29221 aaatacttaa agctactcca gcactatggc gataagcccg ttagcgtgac gctacaggag
    29281 ctggcggatg tgttgttctg cacccggcgg catatgcgta atctgttgct tcagatgcag
    29341 gaggcaaagt ggctcatctg gcaatcacag gccggacgtg ggcatcgcgc ccggcttcac
    29401 ctgcgctata aaccagaaca gctgttaagc gaaaaggcgg agcagttgct ggagtctggt
    29461 catgttgatc aggccattca gctgctgggt aaaaataagc accaggtggc gcaactgctg
    29521 cgctcaaaac tgggctatag cgtgcgggca gactatcagc ggctgtgcat cccctattac
    29581 cggacaatgc cgtcgctgtg ccccggcata ccgttgcgtc gctctgagca gcatctggtc
    29641 aggcagattt ttagcggcct gacgcgcata aatgaggaaa aaggtgaagt cgaagccgat
    29701 cttgcccacc actggcggca gattgatcca ctgcgctggc gtttttatct gcgccccgcc
    29761 gtcctctgac atgatggtca ggagctgacg atcgacgcgg ttatcgcttc actgacccgc
    29821 agcgctaagc tgccgttgtt ctcgcacttg cagaccattc aggccaccgg gccgctgagc
    29881 cttgaaatta cgctggcgca cccggataac cgactgccgc tgctgctcag ccatattgat
    29941 gccatgatcc taccgcctga ccatacacaa cgcgctgatt tcccggcaca tcctgtgggg
    30001 actggccctt atgaggtggt ggaaaacaat ggctttcatc tgcaaatgaa ggcctttgac
    30061 cactatttcg gcctgcgcgg gctgctggat gaagtggagg tctttatctg gccgaattta
    30121 acggagacag acaacctggc ggaatcgctg tcggataacg acacggcagc ctggctcagt
    30181 tccagcctga gcgatgagga ttacgtttcc ggacggctta gccaggtatc aggcaaacct
    30241 tctgacaacc tgcgcgagat gtttcttgag cgtggaggat attttttatt atgcgacagc
    30301 cgctccccgc actggcatac cgccgaacat cgccgctggc tgcgggaaac tctcagccct
    30361 tacgccttac tccagcatct gagtgaggca attcgcccct tctgggtacc gggcggcagc
    30421 ctgctgtcct cctggtttca tactattgag gcgggcccgg cctgttcacc ttttatctcg
    30481 tcgtcgccct acgcaaaact tcgtctggcc tatcacgatc agcaccctga atttccaatg
    30541 ctcctggata ttatgcaaga gatcatgcgc cagcagggca ttttacttga gggcgttgag
    30601 ctgaattatg atgactgggc gaatggcaaa accaatgtgg atctctggct ggggacggtc
    30661 aatttcccca ttcccgaaga gtggaacgtc ggtacatggc tactgggctc ccctttactg
    30721 cgccacgcca tcagcggtgg ggatgatgcg ctgctggccc aatgggaaac ccagtggcat
    30781 gccgaaacca tcagcgcgga acaactggtc agggaaacca cccgttcagg ctggctacag
    30841 ccgctttttc accactggat gcgactcaaa agccccgacc gggccagggg gatccacctg
    30901 aataacctgg gatggtttga tttccgatcc acctggattg agccagggcc gtagttcatt
    30961 gatatgactt attttgtaat tagattagtt cgttatttcc agcgtgatcg tggcgtaagc
    31021 ttcaaatgta ccaggttgag gccgcgctcc cgtcgcgctg gcaggcgcgg cagaaaaagt
    31081 caatgagtta gtctcggcgc cgccattatt gacgcccata tccatatcca tttttccgcc
    31141 tgtcacctta accatccgat cccatttgtc ataaatcata attccgacat catcattacc
    31201 cagaactttc atcatatttg cgctggaatc aacgggatca gcattaaatg tcgaatagac
    31261 gatattctca tccaacattc cggtacattt cacctgtacc gttttagtca ctttatgacc
    31321 cgcagcagcg gtgccttgcg ttgtcgagaa atccgcaacc gggatcttac cgaaattcac
    31381 ctctatcacc tggccggaat caatttcaca gctctgcggc gccacgatat cgccaacaat
    31441 tctgacttcc gccaatttgt cggtactggc agtcgaggag ctggcatcaa gccccccgta
    31501 taaattagcc acaatcgtgc caggaatggc aacctgaccg acaaacggtt tattgataag
    31561 gaaagagacc ttgacctccg acccggtata taacgttgcg agattgccct caacggtatc
    31621 ggtataacaa ttcatcccat cttttactac attaggttca gcctcaaagg gaaccgcaat
    31681 aaagcctcgt ccaagaacag caatcgacgt tgcaatactt aggttatcgt taagcgtata
    31741 gtaggtgtaa ccatttctgg tggtatcaat actcagcggc gaacgagcgg tataatagac
    31801 ttcacgaaac gtcgatgaaa aatgggtcaa acagctacag ccaactttat atgattctga
    31861 cgatgttaat gtctccagat ccctgacctc tgttccggct ttattttttt ctgcgggaat
    31921 ccgggcgtca ttgagattaa ggttataaat ataagtccct ttaaccgcat gacaaatgcc
    31981 atcgccagcc cggcaaacag gcgaaataag aaccataaag catgaaaata atattattgt
    32041 ccataagcgc ataattaaat tccttattgg caagtgacgg cttgctgcac cagttcagca
    32101 ttctctgttt tatgacctaa cgtataatta acggcacatg ttgttgattc atcaccgccc
    32161 caacttagag tgaaatgacc gttttccggc atccccgata aatagagttc gccgttatcg
    32221 ccgacaatcc cggttaccgt tccggaatcc agctccgccg acgccatcgc gccaaacggc
    32281 gcaggtttgc cattcacttg catcacatta aacaacacgc gataaccgac atgcgtcaca
    32341 aacgccgctt tcaccacggc gccgcgcgtt ggcaccagat tgactaccgt gttatccagc
    32401 tcaatattgg ctttggcaaa atagttgctg tcaatcgcca tgcggttttc gtcgtacggg
    32461 ttaagctgcg ttttcaccgt atagccccgc cagtctgtag caaccccagt cgtgttttct
    32521 acggtaaggc catcagcacc cggcgcttcc accagcgcga cggtttcccc caactcctgc
    32581 gagaaggtca caccgccgct gtgaaccagg atgccgccgc gggcgccata gttcagcgtt
    32641 tgtgaatcac ggctccaggc ataaccgccg tttactgaac cataagtacc gtcatacccc
    32701 atgctggcgt taccaccata ggtatcctcc ggcgtactgg tccaggattc ctgcacgtta
    32761 taggaaagat tgtggccctc cagcaacgtg ccgccaacgc cagcctgcat tgtgctgtcg
    32821 ttatgattat tttgcgtcat cgagtagtta acgtagctgc tctccttcgc ccctgaaagc
    32881 gggatggaaa ccgtcagcat gaatatctgt tcgtgatcgc tgtcatcgtt gtcgttttta
    32941 ttattgctgc cggaagaacg attcgcagag tcggtatagt tccacgacgc gttccacgaa
    33001 attcgccgcc agctattgct atagccaaac tgcaccaggc gctcgacttc atccgtttgc
    33061 cagtattgct gacggcttaa cgtcagataa atgttgccaa aaccggggcc aaatgattgc
    33121 gtccaggttc cttccacgcg gctacggcgg ttgcccgtct cccagaaatc agagctgttg
    33181 tcctgcctcg atgcccactc gccgagggtg taatagcctt ccgtggaata acggtacccc
    33241 accagacgga aactggtgtc ggtatcatca aaacgtttgg agtagagaaa acgccaggac
    33301 tggccgcttt cattatcacc atcgtcaaag tgtgaacggg cgtgggtcac atcaaacgat
    33361 acggccccga tcgaccccat atctttaccc ataccaagcg cggcggaagc ataatcttcc
    33421 gcaacctgcg tgccgccata gagcgttaat ccccatggca ggccatgcaa cacctgcgcc
    33481 tgaacgacgt taggggtaaa tccgctttca tcgcgcattt caccgacgct aatatcaaaa
    33541 tcggtctggc cttcacgctt cagtatcgcc agcgacgcgt acggctgggt aaagtgctgc
    33601 tcgctgccgt cttcttcttt tatggtgaca tcaagatcgc cgccgccgct ggtggtgttc
    33661 aggtcggtga tctcgaaagc gccctgcggc acggctgact gataaatgac atatctattc
    33721 tgccggatga tgacggtggc gttacttttc gccaccccgc gaaccactgg cgcaaacccg
    33781 ttctggctcg acggtagcat gtcatcgtcg gtatagagtc tgaccccgcg gatctgggcg
    33841 ctatcaaaga cataactcgc cgtccaggtg tcgccgacca taatctggct gcgcagcgcg
    33901 gcgatatcgc gctggacata gctactgatg gagtgatatt ccgtgtcgct gccggtggcg
    33961 ctcagcgtac tgtagttacg caaccgccat gctcccaggt taatcccgtt acgcaggttc
    34021 agataataag agtcatcgtt cccattgtcg taattagact ttaccgtgtg cgatccggaa
    34081 aaatcttaat tgaccatcat cgcattgatg ccctcatccc agcgtgacgg gctgatatag
    34141 tcataggccg ccgtgttcag atagatctgt ggaacagata tatttaacgc cagcttattc
    34201 gcatctaata accaggtggt gccatcaatt aacggaacgg gattcacgca ggctgtatta
    34261 tcgacatcct gcaagccttt caccgcgtct accttaacac catacgacga caatacatcc
    34321 ttaaccgcga caaagcaggg atgcagttcg gcatccggtt gatcctgcac aaaggtcaca
    34381 tcccgtcgtt caaacagttt cccgttaatg acgatatcga ccttataatc gcccggcggc
    34441 aacgcgttgg aacggttaaa ctgatgaata tccacgtcca cggggtgatc gatttccagc
    34501 aaaccagggt taaatagcgt ttccctagcc attgtcggga aagcgatact cagataagca
    34561 cctgaaatca agacgaggca aagacgaggg tgaatcatca agatatcctt atcgcaaaac
    34621 taaagcgctt gcttaacagg gctactaatc gcgccgtaat cattaataaa acgccaggct
    34681 aaagcgtgcc ccgtaacacc agtaggtaaa tccagcgtta atttttcaaa aggctttatc
    34741 atattcaatg gaacatcttt accgtctaca gagacatcca tgatattcat atgaatagga
    34801 ctattatttt ctacaaccag tttacttccc tgtcgatacc atttgacttt agctaccgcc
    34861 ttttccggga taagcgtaat agaggccggg cgccagaata acttgatacg cgttttaatt
    34921 gcgatctcaa gcgtactgct atctttattt ttactggatg gcggaatgtt tttcacatta
    34981 aaccaaaaaa cagattcgcg atcctttggc aactcacccg ctgttttaat aatgcgcagc
    35041 actttttcct gactcggctc aagacgagaa acaggcggaa tgacggtaaa aggtggtttg
    35101 ctcttatcat ccttactgaa aggatcaacc catacttgta ttagataagg caaatcaact
    35161 tctttattgt aaatagaaat agtagagtca ggatcgttgc catgaaaaat gacgcgagtt
    35221 ccaccgacca caatacctgc aaaagcagag ggaagattaa ggcacaggag tgccagaata
    35281 actattttta ttccacgagc aaacatagac aaactcatcc ctggataaaa aagacgccgg
    35341 gcatttatac aactacagtt gttcacaatg gcaggcgtca ataaattaat aaaagacgtt
    35401 taagaagagc gaatcttatt tttggtattc gacagtgaac tgagaatctg cgttagcagt
    35461 acccgcagtg acggttgcgt cagtggcgat ataacgcgcg ataaactcca tagaagccgt
    35521 acccgctgtg gtatcaatcg tgctatacgc agaatcgttg tacagtttaa cttgtgagtt
    35581 atccgcgcgg ttgtaaatac ggatcgctac gccagatgct gtaatggcag cgccgtcacc
    35641 ggtgtaatca cccggggcat cgccattagc agggttgccg atagccaggt cgccatcgct
    35701 gttggaagct tcggtaccat caaaacgaac ggcagcctta gtatacgtag ccgggcaccc
    35761 ggtcaggtcg atatggaact cggtaggcgc agcggtactt cccacgccag caaatgccgt
    35821 tttgttaact ttgcctaaat taacgttttg atcagcggtt tgtggcgtaa cctggcaggt
    35881 gctgtcaacc acttcaccaa ggaagtgaac ggtgccatca gatgccattg cattacctac
    35941 cagcatagta gaagacagaa ccagagcgct ggcaattaaa ttcagtttca ttataactct
    36001 attgatatat tatatatccc gatgtttcat ttaaaaataa ataaaacaca atgtgtctac
    36061 aacggaag
//
LOCUS       DAJVKX010000036        34867 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000036 DAJVKX010000000
VERSION     DAJVKX010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 34867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34867
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.036"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            76..1215
                     /gene="arnB"
                     /locus_tag="OPY25_001773"
     CDS             76..1215
                     /gene="arnB"
                     /locus_tag="OPY25_001773"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HCS0927404.1"
                     /translation="MSDFLPFSRPAMGAEELAAVKTVLDSGWITTGPKNQELEAAFCR
                     LTGNQYAVAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMIVLLGATPVMVDV
                     DRDTLMVTPEHIEAAITPQTKAIIPVHYAGAPADLDAIYALGARYGIPVIEDAAHATG
                     TSYKGRHIGARGTAIFSFHAIKNITCAEGGIVVTDNPQFADKLRSLKFHGLGVDAWDR
                     QSGGRAPQAEVLAPGYKYNLPDFNAAIALAQLQKLDALNARRAAIAAQYHQAMADLPF
                     QPLSLPPWEHIHAWHLFIIRVDEARCGITRDALMASLKTKGIGTGLHFRAAHTQKYYR
                     ERFPTLTLPDTEWNSERICSLPLFPDMTESDFDRVITALHQIAGQ"
     gene            1218..2201
                     /gene="arnC"
                     /locus_tag="OPY25_001774"
     CDS             1218..2201
                     /gene="arnC"
                     /locus_tag="OPY25_001774"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HCS0927405.1"
                     /translation="MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEIL
                     LIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDAD
                     LQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYG
                     CMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLI
                     NLMYDLVTCLTTTPLRLLSLLGSVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTSFTEESHQ"
     gene            2198..4180
                     /gene="arnA"
                     /locus_tag="OPY25_001775"
     CDS             2198..4180
                     /gene="arnA"
                     /locus_tag="OPY25_001775"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HCS0927406.1"
                     /translation="MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGS
                     VSRLAAGLGIPVYAPDNVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFN
                     LHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALT
                     LHHKLCQAARQLLNSILPTMKCGNIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVH
                     NLVRAVAAPWPGAFSYNGSQKFTIWSSRICPDAQGALPGSVISVSPLRVACADGALEI
                     ITGQAGDGITVQGSQLAQTLGLVAGACLNRPPATSGKRRIRVLILGVNGFIGNHLTER
                     LLDEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLNAARIGS
                     SRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNEGDRCDGKIINIG
                     NPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSID
                     NARRCLDWEPSIAMRDTVEETLDFFLRSVDIAERAS"
     gene            4177..5076
                     /locus_tag="OPY25_001776"
     CDS             4177..5076
                     /locus_tag="OPY25_001776"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HCS0927407.1"
                     /translation="MTKVGLRIDVDTLRGTREGVPRLLATLHRHGVQASFFFSVGPDN
                     MGRHLWRLIKPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHE
                     TGLHAWDHHAWQTHSGHWSIRQLEEDIARGITALEAIIGKPVTCSAAAGWRADGRVVR
                     AKEPFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWII
                     SRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPASPESLPLG
                     QIVRGHIPGREGWLGCQQAVSAS"
     gene            5073..6719
                     /gene="arnT"
                     /locus_tag="OPY25_001777"
     CDS             5073..6719
                     /gene="arnT"
                     /locus_tag="OPY25_001777"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HCS0927408.1"
                     /translation="MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREML
                     ASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWL
                     TFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRT
                     GKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFV
                     VVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLL
                     PGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNV
                     KEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWA
                     FVGWYSLCHSPKYLLPAFCPLGLALLFGFSVPDRVMESKQPQFFVEMTQAPLASSRYI
                     LADSVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQNKFVKADDFNAWLNQHRQE
                     GIITLVLSIDKDEDISALSLPPADNVDYQGRLVLIQYRPK"
     gene            6716..7051
                     /gene="arnE"
                     /locus_tag="OPY25_001778"
     CDS             6716..7051
                     /gene="arnE"
                     /locus_tag="OPY25_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HCS0927409.1"
                     /translation="MIGIVLVLASLLSVGGQLCQKQATRPLTTGGRRRHLMLWLGLAL
                     ICMGAAMVLWLLVLQTLPVGIAYPMLSLNFVWVTLAAWKIWHEQVLPRHWLGVALIIS
                     GIIILGSAA"
     gene            7051..7428
                     /gene="arnF"
                     /locus_tag="OPY25_001779"
     CDS             7051..7428
                     /gene="arnF"
                     /locus_tag="OPY25_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HCS0927410.1"
                     /translation="MGVMWGLISVAIASLAQLSLGFAMMRLPSIAHPLAFISGLGAFN
                     AATLALFAGLAGYLVSVFCWQKTLHMLALSKAYALLSLSYVLVWVASMLLPGLQGAFS
                     LKAMLGVLCIMAGVMLIFLPARS"
     gene            complement(7423..7680)
                     /gene="pmrD"
                     /locus_tag="OPY25_001780"
     CDS             complement(7423..7680)
                     /gene="pmrD"
                     /locus_tag="OPY25_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HCS0927411.1"
                     /translation="MEWLVKKSHYVKKRACHVLVLCDSGGSLKMIAEANSMILLSPGD
                     ILSPLQDAQYCINREKHQTLKIVDARCYSCDEWQRLTRKPL"
     gene            complement(7778..9145)
                     /gene="menE"
                     /locus_tag="OPY25_001781"
     CDS             complement(7778..9145)
                     /gene="menE"
                     /locus_tag="OPY25_001781"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HCS0927412.1"
                     /translation="MTFTDWPWRHWRQVRSQAPALRLNDEVLSWRALCERIDALAGGF
                     AAQGVREGDGVLLRAGNQPRTLLAWLALMQCGARVLPVNPQLPQTLLEALVPKLTLRF
                     ALTLEGENAFSGLTVLQLRKSTVAYAVAWQPQRLVSMTLTSGSTGLPKAAVHTCQAHL
                     ASAQGVLSLMPFGPQDDWLLSLPLFHVSGQGIMWRWLFAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLANRAAVTLKAVLLGGAVIPVELTDQASKQGIRCWCGYGLTEFAS
                     TVCAKEADGSDDVGAPLPGREIRIVDNEVWLRAASMAEGYWRDGKLIPLVNDEGWFAT
                     RDRGELNHGRLTIAGRLDNLFFSGGEGIQPEEVERVINAHPLVQQAFVVPVEDKEFGH
                     RPVAVVEYASQAGDVNLAEWVRDKLARFQQPVRWLTLPSELKNGGIKISRRALQQWVC
                     KICKN"
     gene            complement(9142..10104)
                     /gene="menC"
                     /locus_tag="OPY25_001782"
     CDS             complement(9142..10104)
                     /gene="menC"
                     /locus_tag="OPY25_001782"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HCS0927413.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGE
                     ISPLPGFSQETWEEAQTALLTWVNDWLQGSEGLPEMPSVAFGASCALAELTGVLPEAA
                     DYRAAPLCTGDPDDLVLRLADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKAQQFAKYVNPDYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     ADFTFEAEEGVRAVVIKPTLTGSLDKVREQVAAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPGTLPGLDTLHLMQAQQVRPWPGNALPCLKRDELERLL"
     gene            complement(10104..10961)
                     /gene="menB"
                     /locus_tag="OPY25_001783"
     CDS             complement(10104..10961)
                     /gene="menB"
                     /locus_tag="OPY25_001783"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HCS0927414.1"
                     /translation="MIYPDETMLYAPVEWHDCSEGYTDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNVGVIILTGEGDKAFCAGGDQKVRGDYGGYQDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAAENAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAQQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(10976..11734)
                     /gene="menH"
                     /locus_tag="OPY25_001784"
     CDS             complement(10976..11734)
                     /gene="menH"
                     /locus_tag="OPY25_001784"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HCS0927415.1"
                     /translation="MMLHAQHMPGQPGTPSLVFLHGFSGDCREWQPVGEQFHGCSRLY
                     IDLPGHGGSAAIPVGGFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPG
                     LCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRHEPLTEVFHDWYQQPVFASLTAQQ
                     RQALTALRSQNNGETLAAMLEATSLAVQPDLREVLNALAFPFYYLCGERDSKFRALAQ
                     EVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL"
     gene            complement(11731..13401)
                     /gene="menD"
                     /locus_tag="OPY25_001785"
     CDS             complement(11731..13401)
                     /gene="menD"
                     /locus_tag="OPY25_001785"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HCS0927416.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAEN
                     PAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQAGMFASHPSQTLSLPRPTQDIPARWLVSTIDNALAMLH
                     AGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLASDKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTEL
                     QQAQIVVQLGSSLTGKRLLQWQATCVPEEYWVIDNIEGRLDPAHHRGRRLVAKIADWL
                     ELHPAEKRKPWCVEIPRLAELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLN
                     ALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRY
                     HRPENWEELESALAGAWRTPATTVIELVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13487..14782)
                     /gene="menF"
                     /locus_tag="OPY25_001786"
     CDS             complement(13487..14782)
                     /gene="menF"
                     /locus_tag="OPY25_001786"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HCS0927417.1"
                     /translation="MHSITTALENLTRQLSQEIPATPGLCVFDAPFPLNDAFDALSWL
                     ASQSSFPQFYWQQRNGDEEAAVLGAITVFSSLDLAQRFLRQHAQPDLRIWGLNAFEPK
                     EGYLLLPRLEWRRSGGTATLRLHLHSDVSLRDDARLAKAFLASLVGIKPVPALRLSLT
                     SEQHWPDKDGWVKLIQQATHTIAQEAFDKVVLARATDLQFSRPVNAAAMMASSRRLNL
                     NCYHFFMAFSADTAFLGSSPERLWRRRETALRTEALAGTVANHPDNHKAWQLGEWLMK
                     DDKNQRENMLVVEDICQRLQNCTHSLDVLPPQVLRLRKVQHLRRCIWTALNQADDTLC
                     LHQLQPTAAVAGIPREPARCFIEQHEPFEREWYAGSAGYLSTRQSEFCVTLRSAKVTA
                     NVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQMDA"
     gene            complement(14883..15188)
                     /gene="elaB"
                     /locus_tag="OPY25_001787"
     CDS             complement(14883..15188)
                     /gene="elaB"
                     /locus_tag="OPY25_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HCS0927418.1"
                     /translation="MSYQFGESRVDDDLTLLSETLEEVLRSSGDPADQKYIELKARAE
                     QALEEVKNRVSHASDSYYYRAKQAVYKADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15243..15704)
                     /locus_tag="OPY25_001788"
     CDS             complement(15243..15704)
                     /locus_tag="OPY25_001788"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0927419.1"
                     /translation="MIDWQDLHHSELTVPQLYALLKLRCAVFVVEQRCPYLDVDGDDL
                     VGDNRHILGWHQDELVAYARILKSDNESDPVVIGRVIVSDAWRGAKLGQQLMAKTLES
                     CGRHWPDKPLYLGAQAHLQPFYARFGFIPVTDVYDEDGIPHRGMAREVHQA"
     gene            15765..16682
                     /gene="rbn"
                     /locus_tag="OPY25_001789"
     CDS             15765..16682
                     /gene="rbn"
                     /locus_tag="OPY25_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HCS0927420.1"
                     /translation="MELIFLGTSAGVPTRSRNVTAILLHLQHPTQPGVWLFDCGEGTQ
                     HQMLNTAFHPGKLERIFISHLHGDHLFGLPGLLCSRSMAGNPHPLTVYGPQGVREFIA
                     TTLRLSGSWTDFPLQIEEISAGDILDDGLRKVTAFRLEHPLECYGYRVVEHDKPGALN
                     ARALKAAGVTPGPLFQALKAGKTVTLADGRQINGADYLAPAVAGKSVAIFGDTAPCEA
                     ALALAQGVDVMVHETTLDASMEEKANARGHSSTRQTATLAREAAVGRLIMTHISSRYD
                     DKGCQRLLAECRAIFPATELAYDFSVFPV"
     gene            16748..17752
                     /locus_tag="OPY25_001790"
     CDS             16748..17752
                     /locus_tag="OPY25_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheV"
                     /protein_id="HCS0927421.1"
                     /translation="MDNFQKDIDDRANLTLSNRFELLLFRLGTSLHEQKSELFGINVF
                     KLREIIPMPAFTRPAGMKAPLLGMVNIRDQVIPVIDLPAVAGCKPETGLNILLITEYV
                     RSVQAFAVESVENIMRLDWQQVHTAEKAVNGRYITSIACLDDNKETNNLALVLDVEQI
                     LYDIVPSSHDLRATNLKTNKFYITPGAVAIVAEDSKVACAMLEKGLNAMEIPHQMHVT
                     GKDAWERIQQLAQEAEAEGKPISEKIALVLTDLEMPEMDGFTLTRKIKTDERLKKIPV
                     VIHSSLSGSANEDHVRKVKADGYVAKFEINELSSVIQEVMERAAQNISGPLVSRQLLS
                     "
     gene            complement(17893..19350)
                     /gene="nuoN"
                     /locus_tag="OPY25_001791"
     CDS             complement(17893..19350)
                     /gene="nuoN"
                     /locus_tag="OPY25_001791"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HCS0927422.1"
                     /translation="MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQ
                     EEFYLLVLIASLGGILLANANHLAALFLGIELISLPLFGLIGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLHEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPFRGPDADSLYSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPTNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISLVQLATPLM"
     gene            complement(19357..20886)
                     /gene="nuoM"
                     /locus_tag="OPY25_001792"
     CDS             complement(19357..20886)
                     /gene="nuoM"
                     /locus_tag="OPY25_001792"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HCS0927423.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMELTLALGL
                     QLWLQGGYSLTQSAGIPQWQSEFVLPWIPRFGISIHLALDGLSLLMVVLTGLLGVLAV
                     LCSWREIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYKATSVWTFNYEELLNTPMSHG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFTQYDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERLHTRDMRMMGGLWGKMKWLPALSMFFA
                     VATLGMPGTGNFVGEFMILFGSYQVVPMITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELLGMSLRELFIILLLVVLLVLLGFYPQPILDTSHSAMSNIQQWFVNSVTTTR
                     P"
     gene            complement(21200..23041)
                     /gene="nuoL"
                     /locus_tag="OPY25_001793"
     CDS             complement(21200..23041)
                     /gene="nuoL"
                     /locus_tag="OPY25_001793"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HCS0927424.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENLSATIGVGSVGLAALV
                     TAFVGMDFFANGKQAFSQPLWTWMSVGNFNIGFNLVLDGLSLTMLSVVTGVGFLIHMF
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLSDNLLLMYLGWEGVGLCSYLLIGFYYSD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEILHLVGIIGAITLVMAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYACFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAGKG
                     ITHHLPLIVLMILSTFVGALIVPPLQGVLPQTTELAHGRVLTLEITSGVVAIAGILIA
                     AWLWLGKRTLVTSIANSAPGHLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     ALMNIPAILSRFAGKGLVLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(23038..23340)
                     /gene="nuoK"
                     /locus_tag="OPY25_001794"
     CDS             complement(23038..23340)
                     /gene="nuoK"
                     /locus_tag="OPY25_001794"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HCS0927425.1"
                     /translation="MIPLTHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(23337..23891)
                     /gene="nuoJ"
                     /locus_tag="OPY25_001795"
     CDS             complement(23337..23891)
                     /gene="nuoJ"
                     /locus_tag="OPY25_001795"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HCS0927426.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLVISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAVLSAI
                     MLAVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRADDRAKRKTEERA"
     gene            complement(23902..24444)
                     /gene="nuoI"
                     /locus_tag="OPY25_001796"
     CDS             complement(23902..24444)
                     /gene="nuoI"
                     /locus_tag="OPY25_001796"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HCS0927427.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFELGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(24459..25436)
                     /gene="nuoH"
                     /locus_tag="OPY25_001797"
     CDS             complement(24459..25436)
                     /gene="nuoH"
                     /locus_tag="OPY25_001797"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HCS0927428.1"
                     /translation="MSWITPDLIEILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLSFAIVP
                     VSPNWVVADLNIGILFSLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTVSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTVSALMVTLFFGGWHGPFLPPFVWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLINLLVTAAVILWQAQ"
     gene            complement(25433..28159)
                     /gene="nuoG"
                     /locus_tag="OPY25_001798"
     CDS             complement(25433..28159)
                     /gene="nuoG"
                     /locus_tag="OPY25_001798"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HCS0927429.1"
                     /translation="MATIHVDGKEYEVNGADNLLQACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPATDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASIESNFALRELVGA
                     ENFYTGIARGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNTAPAVDGIDSDLQNKIDVIVQALAGAKKPLIISGTNAGSSE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGMMGGGSLDDALGELETGSADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDNKTIMLESWRWLHSLHSTVENREVDWTQLDHVIDAVIAAMPQ
                     FAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDKDTMFAFSMEG
                     NNQPTAPRSEIPFAWAPGWNSPQAWNKFQDEVGGKLRHGDPGVRLIEATEGGLDYFTT
                     VPASFQAQDGQWRIAPYYHLFGSDELSQRSPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEISEGLAAGQVGLPMGMPGIAPVLAGARLEDLREAQQ"
     gene            complement(28190..29527)
                     /gene="nuoF"
                     /locus_tag="OPY25_001799"
     CDS             complement(28190..29527)
                     /gene="nuoF"
                     /locus_tag="OPY25_001799"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HCS0927430.1"
                     /translation="MKNVIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVSQVKDAGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVHLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGVWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTIAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIG
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(29524..30024)
                     /gene="nuoE"
                     /locus_tag="OPY25_001800"
     CDS             complement(29524..30024)
                     /gene="nuoE"
                     /locus_tag="OPY25_001800"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HCS0927431.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEKHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIYAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHITGY
                     QGIQAALEKNLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHSHLTPEAIPE
                     LLERYK"
     gene            complement(30027..31829)
                     /gene="nuoC"
                     /locus_tag="OPY25_001801"
     CDS             complement(30027..31829)
                     /gene="nuoC"
                     /locus_tag="OPY25_001801"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HCS0927432.1"
                     /translation="MVNNMTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHL
                     ISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMM
                     PQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMKRGTDNEDFMFL
                     NLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLD
                     SYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENF
                     DFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSF
                     AHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(31916..32578)
                     /gene="nuoB"
                     /locus_tag="OPY25_001802"
     CDS             complement(31916..32578)
                     /gene="nuoB"
                     /locus_tag="OPY25_001802"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HCS0927433.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLHD
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQPERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(32594..33037)
                     /gene="nuoA"
                     /locus_tag="OPY25_001803"
     CDS             complement(32594..33037)
                     /gene="nuoA"
                     /locus_tag="OPY25_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HCS0927434.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     HKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR"
     gene            complement(33430..33582)
                     /locus_tag="OPY25_001804"
     CDS             complement(33430..33582)
                     /locus_tag="OPY25_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927435.1"
                     /translation="MPICTRLTAQIVKVAVNQPVAIRSSMWAKNNQNIHFMNLHVKKL
                     EKLLLF"
     gene            complement(33662..34600)
                     /gene="lrhA"
                     /locus_tag="OPY25_001805"
     CDS             complement(33662..34600)
                     /gene="lrhA"
                     /locus_tag="OPY25_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HCS0927436.1"
                     /translation="MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLSEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
                     LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYV
                     ASTLLAVRAAVKAGLGVTARPVEMMSPDLRVLGAADGLPPLLDTEYMLCRDPNSQNEL
                     AMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE"
BASE COUNT         7941 a        10093 c         9362 g         7471 t
ORIGIN      
        1 aatgcgttaa aaaataagcc cttttctatt gccgaaatat ttgaaaagcg gctttcaatg
       61 gctgaaggaa aaatgatgtc ggactttttg cctttctccc gtccggcgat gggcgcggaa
      121 gagctcgctg ccgttaagac cgtactggac tcaggttgga taacaaccgg cccgaaaaat
      181 caggaactgg aagcggcgtt ttgtcggcta acaggcaatc aatatgccgt tgccgtcagt
      241 tcagccactg ccggtatgca catcgcgttg atggcgctgg gtattggtga aggcgacgag
      301 gtcattacac cgtcaatgac gtgggtttct acgctaaata tgatcgtttt actcggcgcg
      361 acccccgtca tggtcgatgt cgatcgcgat acgctgatgg tcacgcctga acatatcgaa
      421 gccgcgatta cgccacaaac caaagcaatt atccccgtcc actacgctgg cgcgcccgcc
      481 gatctggacg ctatttacgc tcttggcgcg cgttatggca ttccggtgat tgaagacgcg
      541 gcgcacgcga caggaaccag ctacaaaggt cgccacattg gcgcccgggg caccgcgatt
      601 ttctccttcc acgccattaa gaacattacc tgcgctgaag gcggtatcgt cgtcacggat
      661 aacccgcaat tcgccgataa actgcgcagt ctcaagtttc acgggcttgg cgttgatgcc
      721 tgggatcgac agagcggagg acgcgcgcca caagcggaag tcctggcgcc gggctacaaa
      781 tataatttgc ccgacttcaa cgccgctatc gcgcttgccc agttacagaa actggatgcg
      841 cttaacgctc gccgcgccgc catcgcagcg cagtaccatc aggcaatggc agaccttcct
      901 tttcagcctc tgagccttcc gccgtgggag catattcacg cctggcattt attcattatc
      961 cgggtcgatg aagcccgctg cggtattacc cgggatgctc tgatggcatc gctgaaaacg
     1021 aaaggcatcg gcacagggct gcatttccgc gccgcgcata cgcaaaaata ttatcgcgaa
     1081 cgtttcccaa cgctcacgct gcctgacacc gagtggaaca gcgagcggat ctgctcactg
     1141 ccgctcttcc cggacatgac cgagagtgac tttgatcggg tcattaccgc ccttcatcag
     1201 atagcaggac aataagcatg tttgacgccg cccccataaa aaaagtctcg gtggttattc
     1261 ctgtctataa cgaacaggaa agcctgccgg aattgataag acgcaccacc accgcctgcg
     1321 agagtctggg caaagcgtgg gagattttat tgatagatga tggtagcagc gatagctcgg
     1381 cggagctgat ggttaaggcg tcccaggagg ccgatagcca tatcatctct attttactca
     1441 accgtaacta cggtcaacat gcagcgatta tggcggggtt tagccatgta agcggcgatc
     1501 tcatcattac gctggatgcc gatctgcaaa acccgccgga agagatcccg cgcctggtgg
     1561 cgaaagccga tgaagggttc gatgtggtag gcaccgtgcg acagaaccga caggacagcc
     1621 tgtttcgcaa atcggcgtca aaaatcatta atctgctgat ccagcgcaca acgggcaaag
     1681 cgatgggcga ttacggctgc atgttacgcg cctatcgccg ccctattatc gataccatgt
     1741 tgcgctgcca tgaacgcagc acctttatcc ctattctggc caacattttc gctcgtcggg
     1801 ctaccgaaat cccggtgcat cacgctgaac gtgaatttgg cgactctaaa tacagtttta
     1861 tgcgtctcat taacctgatg tatgacctgg tgacctgcct gacgacgacg cctctgcgcc
     1921 tgttgagtct gctgggcagt gttatcgcca tcggcgggtt tagcctgtcg gtattgctta
     1981 ttgtacttcg cctggcactg ggaccgcagt gggcggcgga aggcgtattt atgctctttg
     2041 ccgttctgtt taccttcatc ggcgcgcaat tcatcggtat gggactgctg ggcgaataca
     2101 tcggtcgcat ttataacgat gtccgcgccc gcccccgcta ttttgttcaa caagttatct
     2161 acccggaaag cacgtcgttt actgaggaaa gtcaccaatg aaagccgtta tttttgccta
     2221 tcacgatatg ggatgtcagg gcgtgcaggc cgtactggat gcaggatatg agattgccgc
     2281 aattttcact catgccgaca atcctgcgga aaacaccttt tttggctccg tctcccggct
     2341 ggcggcagga ttagggattc cggtttatgc gccggataac gtaaaccatc ctatctgggt
     2401 cgaccgcatc gctgaacttg cgccagatat tattttttcg ttctattacc gcaacctgtt
     2461 aagcgaagaa attctgcacc tcgccccggc tggcgcgttc aatctgcacg gttctctatt
     2521 gccagcctat cgtggccgtg cgccgctaaa ctgggttctg gttaacggcg aaagcgaaac
     2581 gggcgtaacg ctgcatcgta tggtcaaacg tgccgacgcc ggagagattg tcgccagtca
     2641 acgcgtcgct attgcgcagg acgatgttgc gcttaccctg catcataagc tatgtcaggc
     2701 cgcgcgccag ttacttaata gcatcctgcc caccatgaaa tgcggcaata taccttctgt
     2761 tcctcagcgt gagtctgacg ctacgtatta tggtcgccgc aggccggaag atggccttat
     2821 cgactggcac aaaccggttt ccacggtgca taacctggtg cgggcggtag ccgccccctg
     2881 gcccggcgcg ttcagctata acggctcgca aaaattcact atctggtctt cccgaatttg
     2941 tccggatgcg caaggcgcgc ttcccggctc ggtaatttcg gtctctccgc tgcgggtcgc
     3001 ctgcgccgat ggcgcgctgg agattattac cggccaggcc ggagacggca ttactgtaca
     3061 gggctcgcag cttgcacaga cgcttggtct ggtggcgggc gcgtgtttga accgtccacc
     3121 agcgaccagc ggtaaacgtc gcattcgcgt tctcatcctc ggcgtcaacg gttttatcgg
     3181 caatcatttg accgaacggt tactggatga agagaattac gaggtctacg gtatggatat
     3241 cggcagcaac gccattagcc gattcctgct ccaccctcgc tttcatttcg tggagggaga
     3301 tatcagcatc cactcagaat ggatcgaata tcatgtcaaa aaatgcgatg tcgtactgcc
     3361 gctggtagca attgcaaccc cgattgaata cacccgcaac ccgctgcgcg tctttgaact
     3421 tgattttgaa gaaaacctgc ggattatccg ttattgcgtg aaataccgta aacgcgtggt
     3481 tttcccgtct acctctgaag tgtacggcat gtgtacggac gcctcttttg acgaagacaa
     3541 atcgaatctg atcgtcgggc cggtgaataa gccgcgctgg atttactccg tttccaaaca
     3601 gcttctcgac cgggtgattt gggcttatgg cgaaaaagag ggattgcgct tcacgctttt
     3661 ccgtcccttt aactggatgg ggccgcggct ggatagcctg aacgcggcgc gtatcggcag
     3721 ttcacgcgcg ataacgcagt tgattctgaa cctggtagaa gggacgccga tcaagcttat
     3781 cgacggcggt cagcagaagc gctgtttcac cgatattcgt gacgggatcg aagcattatt
     3841 ccgcattatt gtgaatgagg gcgatcggtg cgatggcaaa atcattaata tcggcaaccc
     3901 tgacaacgaa gccagtattc aggaactggc gacgctgttg ctcgacagtt ttgataagca
     3961 tccgctgcgc tgccatttcc caccatttgc cggtttccag gtcgtcgaaa gccgtagtta
     4021 ttacggcaag ggttatcagg atgtcgcaca ccggaaaccc agtatcgaca atgccaggcg
     4081 ctgtctggac tgggagccgt ctattgcgat gcgtgatacg gttgaagaaa cgctggactt
     4141 ctttctgcgt agcgtcgata tcgcggaacg cgcatcatga cgaaagtcgg tttacgcatt
     4201 gacgttgata ccttgcgagg aacgcgtgaa ggtgttcccc ggctgctggc gacattgcat
     4261 cgccacggcg ttcaggccag ctttttcttc agcgtcgggc cggacaatat gggacgccat
     4321 ctttggcgtc tgataaaacc gcgattttta tggaaaatgc tacgttcaaa cgccgcctcg
     4381 ctctacggtt gggatatcct gctggccggc accgcctggc cgggaaaaaa tatcggcaac
     4441 gctaatgccg ggattattcg tgaaacggca acataccatg agacgggact acatgcctgg
     4501 gatcaccatg cgtggcagac tcacagcggc cactggagta tccgccagct tgaagaagat
     4561 attgcgcgcg gcataacggc gcttgaggcc attatcggaa aacccgtcac ctgctcagcc
     4621 gcggccggct ggcgagcgga tgggcgcgtt gttcgtgcga aagaaccgtt caacctgagg
     4681 tataacagcg attgccgtgg aaccacctta ttccgtccgc tactgatgcc gggccagaca
     4741 gggacgccgc aaatcccggt caccttaccc acgtgggatg aggttatcgg ccccgccgtt
     4801 caggcgcagt cgttcaatac ctggattatt tcccgtatgt tgcaggacaa aggcacgccg
     4861 gtatatacca tccatgcgga agtcgaaggt attgtccatc agccgctgtt tgaagatttg
     4921 ctcgttcgtg cacgcgatgc ggggatcacc ttttgtcctc tgggcgaact gctgccggca
     4981 tcgcctgagt ctctgccgtt ggggcaaatt gtacgtggac acatccctgg ccgtgaaggt
     5041 tggctggggt gtcaacaggc agtgagcgcc tcatgatgaa atcgatacgc tattatctgg
     5101 ctttcgccgc gtttatcgcg ctctactatg ttattcctgt caacagccgc ctgctctggc
     5161 agccggatga aacgcgctat gccgaaataa gtcgggagat gctggcgtct ggcgactgga
     5221 tcgtgccgca ttttctggga ttacgttatt ttgaaaaacc gatagccggt tactggataa
     5281 acagtctggg tcagtggctt tttggcgcta ccaattttgg cgtgcgggcc ggcgctattt
     5341 taacgacatt gctggccgca gcgctggtgg cgtggctgac gttccgctta tggcgggata
     5401 aacgtaccgc gttgctcgcc tccgtgatct ttctctccct ctttgccgtt tacagtatcg
     5461 ggacgtatgc ggtactcgac ccgatgatcg cgctttggct tacggccggg atgtgttgtt
     5521 tctggcaggg gatgcaggcc acgacccgaa cgggcaagat tgggatgttt ttgctactgg
     5581 gcgcaacctg cggtctgggt gtattaacta aagggttcct cgccctggcc gtaccggtgg
     5641 tgagcgtgct gccgtgggtt attgttcaga aacgctggaa ggactttttg ctttacggct
     5701 ggctggcggt cttgagctgc tttgtggttg tccttccctg ggcgatcgcc attgcgcgac
     5761 gcgaagccga tttctggcat tactttttct gggtggagca tatccagcga ttcgccatga
     5821 gcgatgccca gcataaagcc cctttctggt actatctgcc ggtgctgctc gcgggaagtt
     5881 taccgtggct ggggttactg cctggcgcgc ttaaactggg ctggcgcgag cgaaacggcg
     5941 cattctattt gctcggatgg acgatcatgc cgcttctctt tttcagcatt gcgaaaggga
     6001 aactgcccac ctatgttctt tcctgtttcg caccgatagc gatactcatg gcgcgcttcg
     6061 tcctgcataa cgtaaaagaa ggcgtcgccg cgctacgtgt caacggcggg atcaacctgg
     6121 tgttcgggat aatcgggatc gtcgcggcgt ttgtcgtctc ctcatggggc ccgctgaaat
     6181 cgccggtgtg gacgcatatc gaaacctata aagtgttttg cgtctggggc gtctttactg
     6241 tttgggcgtt tgtgggctgg tatagcctct gtcatagccc aaaataccta ttacccgcgt
     6301 tttgtccgct gggactggcg ctgctgttcg gcttttccgt ccccgacagg gtgatggagt
     6361 ccaaacagcc acagtttttt gtcgaaatga cccaggcgcc tttggcatca agccgctata
     6421 ttcttgccga cagcgtgggc gtcgccgccg ggctggcctg gagtctgaaa cgagacgata
     6481 ttatgctcta cggacacgcg ggcgaactca ggtatggtct tagctatcct gatgtacaga
     6541 ataaattcgt taaagccgac gattttaacg cctggctcaa ccaacatcgt caggagggca
     6601 ttattacgct agtactttca atagacaaag acgaagacat cagcgcactt tcccttcccc
     6661 ctgcggacaa tgttgattat caggggcgtc tggtgttaat tcagtatcgg cctaaatgat
     6721 cggcatcgtt ctggtgcttg ccagtctgct cagcgttggc ggtcagctct gccagaagca
     6781 agcgacacgg ccattgacga cgggcggacg ccgccgtcac ttgatgctgt ggctgggcct
     6841 ggcgctgata tgcatgggtg cagcgatggt gctgtggctg ctggtgctac aaaccctgcc
     6901 ggtgggaatt gcttacccga tgttgagtct gaattttgtc tgggtcacgc tggcggcctg
     6961 gaaaatctgg catgaacagg ttctgccccg ccactggttg ggcgtcgcat taattatcag
     7021 cggcattatc attctgggga gtgcggcata atgggcgtaa tgtggggact gataagcgtt
     7081 gcgattgcct ccctcgccca gttgagttta ggattcgcca tgatgcgact gccatcgata
     7141 gcgcatccac tggcgtttat ttccgggctg ggcgcattta atgccgcgac cctggcgcta
     7201 ttcgccggtt tggcgggata tctggtttcc gtcttctgct ggcagaaaac attacacatg
     7261 ctcgcgctca gcaaagccta tgcgctgctg agtctcagtt atgtgcttgt ctgggtagcc
     7321 tcaatgttgt tacccggttt gcaaggcgct ttcagcctaa aagcgatgct cggcgtattg
     7381 tgcattatgg cgggggtaat gctgattttt ctgcccgcca gatcataatg gcttgcgcgt
     7441 caaccgctgc cattcgtcgc aggaataaca gcgtgcatca acgattttta aggtctggtg
     7501 tttttcccga ttaatacaat actgcgcatc ctgtaaaggc gacaggatat cgccgggact
     7561 cagtaatatc atggaattcg cctcggcgat catttttagc gaaccgccgc tatcgcacag
     7621 caccagaaca tggcacgccc tctttttgac ataatgcgat ttcttaacca accattccat
     7681 agcgcccccg tttcacgctg attgttcata acacgttaca catcaacgga taaacaaaac
     7741 ggcaatagcg atggaatggt tgtatattaa cctaacatta atttttacag atcttacaca
     7801 cccactgctg gagcgcacgg cgagatattt taatccctcc gtttttcagt tctgacggca
     7861 gcgtcaacca gcgaaccggc tgttgaaaac gcgccagctt atcgcgaacc cattcagcga
     7921 ggttcacgtc tccggcctgc gatgcatact ccacaaccgc aacgggacga tggccaaact
     7981 ctttatcttc taccggcacg acaaaggctt gttgcaccag cggatgcgcg ttaataacgc
     8041 gttcgacttc ctccggctga atgccttcgc cgccgctaaa gaacaagttg tccagccgcc
     8101 cggcgatggt tagcctgccg tggttcagct cgccgcgatc gcgcgtggca aaccagcctt
     8161 cgtcattaac cagcgggatc agtttgccat cacgccagta accttccgcc atactggcgg
     8221 cgcgcagcca gacttcatta tcgacgattc tgatctctct gccgggaagc ggcgcgccca
     8281 catcatccga accatcggcc tctttggcgc ataccgtaga cgcgaactcc gtgagcccat
     8341 acccgcacca gcagcgaatc ccttgtttgc tggcctggtc ggtgagttca accggaatca
     8401 ccgcgccgcc gagcaaaacg gctttcagcg tcaccgccgc ccgattcgcc aacagccgcc
     8461 acagctgcgt cggcaccaac gaagcatgag tacaacctgc cagcatctgc tccagcggtt
     8521 gcttatcgcg taccgtcatg cgcgccccgg cgaagagcca acgccacata ataccctgcc
     8581 cggatacatg aaacagcggc agcgatagca gccagtcatc ctgagggcca aacggcatta
     8641 gcgaaagcac cccctgcgcg ctggcaagat gcgcctggca cgtatgtaca gccgcttttg
     8701 gcaatcctgt ggaacccgat gtcagcgtca tggaaactag acgctgcggt tgccaggcca
     8761 cagcatacgc cactgtactt ttccgcaact gcaacacggt taatccggaa aacgcgtttt
     8821 cgccttccag tgtcagcgca aaacgcagcg ttaacttcgg caccagcgcc tccagcaacg
     8881 tctggggcaa ctgcgggttg acgggcagaa cccgcgcgcc gcactgcatc agcgcaagcc
     8941 atgccaacag agtgcgcggc tgattcccgg cgcgcagcag gacaccgtcg ccctcccgta
     9001 cgccctgcgc ggcaaacccg cccgccagcg catcaatacg ctcacagagg gcgcgccagc
     9061 ttagcacttc atcgttcagg cgcagagcgg gcgcctgact gcgaacctga cgccagtggc
     9121 gccacggcca gtccgtgaat gtcataacag tcgttccagc tcatcacgct tcagacaagg
     9181 caacgcgtta ccaggccagg ggcgaacctg ttgcgcctgc atcagatgca aggtatccag
     9241 tccgggcagc gttcccggcg tcaaccaggc ggcaatccgc gccagttgcg tcaggccgag
     9301 gctggactcg atcgaagagc tgatgaccgc cgtcagtccc aacgcatggg cggcagcgac
     9361 ttgctcacgc actttatcaa gcgatccggt cagcgtaggt ttgataacca cagccctgac
     9421 gccctcttcg gcttcaaagg tgaaatccgc ttcgcgcaga ctttcgtccc aggcaatcgc
     9481 gatgccggtt tcacgggcaa aggcgcggga atcatcccgc gtcttacacg gttcttcgag
     9541 aaaggcgata cgagcgcggt aatccggatt aacatacttt gcgaactgtt gggcttttag
     9601 cggcgtccag gcgcgattcg catccagacg cagatgcaga tccgggatcg cctccagcag
     9661 caaattaacc accatgccgt cgcgtaccgc ttcatagaga cccactttga ccttagcgat
     9721 tttctcgccg ggcatatcgg caagccgcag taccaaatcg tcaggatcgc cagtgcataa
     9781 cggcgcggcg cgatagtccg ccgcctccgg caagacgcca gtcagttccg ccagcgcgca
     9841 gcttgcgcca aacgcgaccg aaggcatctc cggtaatccc tcgctcccct gaagccagtc
     9901 attcacccat gtcaggagcg ccgtctgcgc ctcttcccac gtttcctgac tgaagcccgg
     9961 cagcggggag atctctcccc acccttcacg ctcgccgtca cgcagacaaa catacagccc
    10021 gtcgcgagtt tttaaccgcc tgtcgcgcag aaccaccccc gcgtccatgg ggatctgcca
    10081 gcggtatacc tgcgcgctac gcattatggg ttccgtttga atttgctgaa gtcaggctga
    10141 cgcttctggt taaaggcgtt acggccttcc tgcccttctt ccgtcatgta gaacagcatg
    10201 gtagcgttgc cggccagctc ctgcagcccg gcctgaccgt cacaatcagc attcagcgcc
    10261 gctttcaggc aacgcagcgc catcggactg ttttgcaaca tttcgcggca ccagcgcacg
    10321 gtctcttttt ccagatccgc cagcggaacg acggtgttaa ccagccccat atccagcgcc
    10381 tgttgcgcat cgtactggcg gcacaggaac cagatttcac gcgctttctt ctgaccaacg
    10441 atacgcgcca tatacgaagc gccccagccg ccgtcaaagg agccgacttt cggaccggtc
    10501 tggccgaaga tggcgttttc ggccgcgatg gtcaggtcgc acatcatgtg cagcacatga
    10561 ccaccgccga tggagtaacc cgcgaccatc gcgacaaccg gttttggaca ggtgcgaatc
    10621 tggcgctgga agtccagcac attcaggtga tgcacgccgg agtcatcctg ataaccgccg
    10681 taatcgccgc gcaccttctg gtcgccgccc gcgcaaaacg ctttatcgcc ttcgccggtc
    10741 agaataatca cgcccacgtt gtcgtcgtaa cgggcatccg ccagcgcctg aatcatctct
    10801 ttgacggtca acggacgaaa tgcattgcgc acctgcggac gattaatggt gatttttgca
    10861 ataccgtcgg tggatttttc ataacgaatg tcggtgtaac cctccgagca gtcgtgccat
    10921 tctaccggtg cgtaaagcat tgtttcatca ggatagatca tagtgtgtcc tttagtcaga
    10981 gacgcagaat ctgagccaga ctgtctacca cgccagcggg gttttcccgg tgcgcgttgt
    11041 gtccggcgtt acgaatgaca tggcatgtcg ccgccacttc ctgcgccagg gcgcggaatt
    11101 tgctgtcgcg ttcgccacat aaataataaa acggaaatgc cagcgcgtta agcacctcgc
    11161 gtaaatccgg ctggacggca agcgatgtcg cctccagcat cgcagccagc gtttcgccgt
    11221 tattctggct acgcagcgcc gttagcgcct gcctttgctg cgccgtcagc gaggcgaaca
    11281 ccggctgctg ataccagtcg tgaaaaacct cagtcaaggg ttcatgacga aaacgctctg
    11341 cccagcgccc gtcggacaat cgtctttcag cgcgcgcctg ttcattttgc agccccggat
    11401 gaccgccttc gaccaccagg ccgcacaggc cgggtattcc ctggcaggct gccatcatcg
    11461 ccacacggcc gccaagggag tatcccacca accaaaactt tagtatgttg taactaatta
    11521 acgtggcgcg cagtaatctg atgacatcgg caaagccgcc gaccggaata gccgcagatc
    11581 cgccatgtcc tggtaagtca atataaagcc gcgaacagcc gtgaaactgt tcgccaaccg
    11641 gctgccattc gcggcaatcg ccagaaaaac cgtgcaggaa aaccagcgag ggcgtcccag
    11701 gctgtccggg catgtgctgc gcgtgcaaca tcatagatgg cttacctgag ccaaaagttg
    11761 ctgcagcgtc tgcgcgccat ccgtatcgtt taccaccagc tcaatcaccg ttgtcgccgg
    11821 ggttcgccac gcgccagcca gcgcagactc cagttcttcc cagttttccg ggcgatgata
    11881 gcgcaggtta aacatggcgg ccgcatggtc aaaatggacg ttttgcggca tcagataaaa
    11941 gcgctcacgc ttactttgcg gcgtcggcag cagggaaaag atctgcccgc cgttattgtt
    12001 gaccacaatc aacacaaacg gcgcggatac ctgacgtagt aacgccagcg cgttaagatc
    12061 gtacagcgcg gataaatcac cgacgatagc caacgtcgat ttggcgctgg cgcgctgcac
    12121 gcccgccgct gtggaaagca ggccgtcaat gccgctcgcc ccgcgattgc tgtataccgg
    12181 atagccggcc ggcaactgtg acagcgcgtc gatcagacgc accaccagac tattgcccac
    12241 gaacaattgc ccctgctccg gcagatagtc gcggatacgg tgcgccagct gcgcttcgcc
    12301 aaaggtgtct cgctgcgcga ccacccgttg ccacgccagt tccgccagac gcgggatctc
    12361 tacacaccac ggtttacgtt tttccgccgg atgcagttcc agccaatcgg cgattttcgc
    12421 taccagtctg cgtccacgat ggtgcgccgg gtccagacga ccttcaatat tgtcgattac
    12481 ccagtactct tccggcacgc aggttgcctg ccattgcagt aagcgttttc cggtaaggct
    12541 actgccaagc tggacgacaa tctgcgcctg ctgcagttcg gtcaccgctt tggcgttgcc
    12601 gagccacagg tcggcgcacg gcagcggctg cccggtttgc gacaatacgt cgccaattaa
    12661 tggccatccc agagtttgcg cccactgcgc cacttttttg ccttcttccg cgctcatacg
    12721 cccggcgaca acgacaccgc gtttttgtcg ccagaagaac cagtcgcgct gtttgtcgct
    12781 tgccagtcga cgcgcttcgc gcagccaggg tttttcatcc tgccaccagt cgccgagacg
    12841 ctgctgccag accagaccgg tgtcattcat atcgccatac agcggttcgg caaaaggaca
    12901 gttaatgtgc agcgcgcccg catgaagcat ggcgagcgca ttgtcgatgg tcgacaccag
    12961 ccagcgcgcc ggaatatcct gcgtgggacg cggcaacgac agagtttggg aggggtgcga
    13021 ggcaaacatc cccgcctgac ggatcgcctg gttggcgccg cagtcaatca gctccggcgg
    13081 gcgatcggcg gtaagtaaaa tgagcttctc gcccgtcaga cccgcctcaa tcagcgccgg
    13141 atagaggttc gccacggcgg tacctgaagt gacaataacg gcaaccggct gttggctgac
    13201 tttcgccagc cctaacgcca aatgaccaag cccacgctca tcaaagtgcg tatggtgaat
    13261 aaaagcagga ttctctgccg ccgccaacgt gagcggcgtg gaacgggaac caggggcgat
    13321 acaaacatgc ctgacgccat gacgggttaa ggcttccagg atgaccgccg cccagcgccg
    13381 gttaaatgca cttactgaca tgagtttgtc cggtatcaat cattgggact aagtataaag
    13441 agctgcaaaa atggattatt gatatgggtc gggaatatgt gactcattac gcgtccatct
    13501 gcaataaggt acgtaacccg gccgctttat tatctatttc ctgccattcc tgttccggat
    13561 cggagccgcg gacgattccc gcgccggcat acaaccgcac cacattggcc gtcactttgg
    13621 ctgaacgtaa cgtcacgcaa aactcacttt gccgcgtgga gagatagcct gccgacccgg
    13681 cataccattc acgttcgaac ggctcatgtt gttctataaa acaacgcgcg ggttcacgag
    13741 ggatcccggc gaccgctgcg gtaggctgta actggtgcag gcagagcgtg tcgtccgcct
    13801 gattaagcgc cgtccagata cagcggcgca aatgctgtac cttgcgcagt ctgagcacct
    13861 gcggcggcag cacatccagc gagtgggtgc agttttgcag tcgctggcag atgtcttcga
    13921 caaccagcat attttctcgc tggtttttat cgtctttcat taaccattcg ccaagctgcc
    13981 aggctttatg gttatccgga tggttcgcca ccgtcccggc cagcgcttcg gtacgcagcg
    14041 ccgtttcacg acgccgccag agccgctccg gcgatgatcc cagaaaggcg gtatcggcgg
    14101 aaaaggccat aaaaaagtgg tagcagttga gatttaaacg acgactggac gccatcatcg
    14161 cggcggcatt gaccggacgg gagaattgta agtcggtggc ccgcgccagc acaactttat
    14221 caaacgcctc ttgcgcaata gtgtgggtgg cctgctgaat cagcttcacc caaccgtctt
    14281 tgtccggcca gtgttgttcg ctcgtgagcg aaaggcgcag cgccggaaca ggcttaatac
    14341 cgaccagaga agcgagaaac gctttcgcca ggcgcgcatc atcgcgtagc gaaacgtcac
    14401 tgtgcagatg taagcgtaag gtcgccgtac caccgctacg tcgccactcc agcctcggca
    14461 gcaataagta gccctctttc ggctcgaacg cattcagccc ccaaatacgc aggtcaggct
    14521 gcgcgtgctg acgtaaaaac cgttgcgcca gatcgagcga tgaaaagacg gtgatggccc
    14581 cgagaacggc agcttcttcg tcgccattgc gctgttgcca gtagaattgc ggaaaggatg
    14641 actggctggc cagccagctc aatgcatcga aggcatcgtt taaagggaaa ggcgcatcga
    14701 aaacgcaaag ccctggcgtc gccggtatct cttgcgatag ctgacgcgtc agattttcca
    14761 gcgcagtagt aatagaatgc acgcggcccc tccctgttaa aaaccccaca ttatacgggg
    14821 tactgcccta aaaaagcagt acctcattta gggagggttg caattctgtt cagtgggggg
    14881 atttagcgcc gcgccagcag cagtccaagc accagtccta ccgccgcgcc tacgccaata
    14941 ccctgccagg gtttttcatg aacgtagtca tccgctttat aaacggcctg ctttgcccgg
    15001 taataatagc tatccgacgc atggcttacg cggtttttca cctcttccag cgcttgttcc
    15061 gcgcgggctt tcagctcaat gtatttttga tcggcgggat cgcctgagga acgtaaaacc
    15121 tcttccagcg tttcgctgag caaagtcaga tcatcatcaa cacgtgattc accaaattga
    15181 tatgacattc tcattctccg ttgtgttaac acctgctcct aactatagtc aacggtttcg
    15241 gtttatgcct gatgaacctc ccgcgccatt ccccggtgcg gaatgccgtc ttcgtcataa
    15301 acatcggtga cgggaataaa accaaaccgc gcataaaaag gttgcagatg cgcctgcgcc
    15361 cccagatata gcggcttatc cggccagtgc cgcccacaag attccagcgt tttcgccatt
    15421 aattgctggc ccagtttcgc ccctcgccag gcatcgctga cgatcacccg gccaatgaca
    15481 accgggtctg attcgttatc acttttcaga atcctcgcat acgccaccag ctcatcctga
    15541 tgccagccca gaatatgccg attgtcgccg actaaatcat cgccatccac atccaggtaa
    15601 ggacagcgct gttctaccac aaagaccgcg cagcgcaatt tgagtaacgc gtaaagttga
    15661 ggaacagtaa gttcgctatg gtggagatcc tgccagtcaa tcatgatgcg ctcctgtgtt
    15721 gtggtaatct tgggttaaac gataaccaaa cgcgtatgga caagatggaa ttaatttttt
    15781 taggtacgtc cgcaggcgtt cccacacgct cacgcaatgt aacggcaatt ttattacatc
    15841 tgcaacatcc aacgcagccg ggagtatggc tttttgattg cggcgaaggg acacagcatc
    15901 aaatgcttaa taccgcgttt catcccggta agcttgagcg catttttatc agccatcttc
    15961 acggcgatca tctgtttggc ctgccgggtc tgctatgcag ccggtcgatg gcggggaatc
    16021 cccatccgct aaccgtatac gggcctcaag gcgtgcgtga gtttattgca accacactgc
    16081 gccttagcgg ttcatggacc gattttccgt tgcaaattga agaaattagc gctggcgata
    16141 ttcttgacga cggtctgcgt aaagtgaccg cattcaggct ggagcatcca ctggagtgct
    16201 acggatatcg cgttgttgaa catgacaagc ctggcgcgct gaatgccagg gcgttaaaag
    16261 ccgcaggcgt tacgcccggc ccgctgtttc aggcgttgaa ggcaggaaaa accgtcacgc
    16321 ttgccgatgg aaggcagatc aatggcgccg actaccttgc tcccgccgtg gccgggaaat
    16381 cagtggcgat tttcggcgat accgcgccct gcgaggccgc cctcgcactg gcgcagggtg
    16441 tggatgtgat ggttcatgaa accacgctgg atgcgtcaat ggaggagaaa gccaacgctc
    16501 gcggacacag ctccacccgt caaaccgcga cgctggcgcg ggaggctgcc gttggtcggc
    16561 tgatcatgac ccacattagc tcacgctatg acgataaagg ctgtcagcgc ttactggcgg
    16621 aatgccgcgc tattttcccg gcgacggagc tggcttacga tttttctgtt ttcccggttt
    16681 agcgctccat tttttgtcct cattgccgat aacactaaaa aaggcaggct ttcataatga
    16741 ggttaggatg gacaattttc agaaagatat tgatgacagg gccaatttaa ccctgtccaa
    16801 ccgttttgaa ctgctgttat tccgtcttgg tacatcgctg catgaacaga agtcagagct
    16861 gttcggtatc aatgtattta agctgcgcga aatcatacct atgcccgcct ttacgcgccc
    16921 ggcaggcatg aaagcgccgc tattgggcat ggtcaatatt cgggatcagg tcattccggt
    16981 gattgatttg ccagcggtag cgggctgcaa gccggaaacc gggctgaata ttttgctgat
    17041 caccgaatat gtgcgcagcg tacaggcatt tgccgtcgag tcggtggaaa atattatgcg
    17101 tcttgactgg caacaggtgc ataccgccga gaaagccgtc aacggtcgct acatcaccag
    17161 tattgcctgc ctggatgaca acaaagaaac caacaacctg gcgctggtgc tcgacgttga
    17221 gcagatcctt tatgatattg tcccctccag ccacgatctg cgcgccacca atctgaagac
    17281 caataaattt tatattaccc ccggcgcggt tgccattgtg gcggaagact ccaaagtcgc
    17341 ctgcgcgatg ctggaaaaag ggctgaacgc gatggaaatt ccgcatcaga tgcatgtgac
    17401 cggcaaggat gcctgggaga gaatccagca actggcgcag gaagcggagg ccgaaggtaa
    17461 gccaattagc gagaaaatcg cgctagtcct gacagacctt gagatgccgg agatggatgg
    17521 ctttacgtta acgcgtaaaa ttaaaaccga tgaacggctg aaaaagatcc cggttgttat
    17581 tcactcttcc ctttccggca gcgccaacga agatcatgtg cgtaaggtga aagccgacgg
    17641 ctacgtggcc aagtttgaga ttaacgaact ctcttcagtg atacaggaag tgatggaacg
    17701 cgcggcgcaa aacatcagcg gcccgctggt aagccggcag ttgctaagtt aaattccggt
    17761 cgctgagacc ttacaggccg gatggcggcg caagcgcctt atccggtcta ccgtcctgag
    17821 tcattttaaa gaatgacatc aggtaataaa aaacccgctt cgtgaagcgg gtttttcgtt
    17881 tttacttatt gcttacatca acggcgtcgc taactgcaca aggctaatca gcggctgcgg
    17941 ccagacgccc agtaccaaca ccagcaacgc ggagatcagc accacgatac cgcctgcgct
    18001 gtactgccag tttgtcggcg cgtcgcgtcc cggttgctgc ggcgcgtgca ggtagagact
    18061 caccgcaacg cgcaggtagt agtacaaacc aatcgcggaa cccaccacca cggcggcgac
    18121 cagccaccac aggctggcct gaacgccgac cgccagcacg tagaatttgc cgataaagcc
    18181 cagcgtcatt gggatacctg ccagcgacag catcatcacc gtcatcaccg cggcaagaac
    18241 cggacggtgc cagaacagac cacggtaaga gtacagggag tcggcatccg ggccgcggaa
    18301 cgggctggac atcaggctga ccacgccaaa cgcgccgagg ctgctgaaca gataaccggc
    18361 cagataaacg cctaccgctt ccatcgacat ctcgccgctc tgcagggcaa tcagcgccac
    18421 cagcagatag ccgaggtgag agatagaaga gtaaccgagc agacgtttga tgttggtctg
    18481 gctcagcgcc atcaggttac cgaagatgat agaggcaaag gcgataatgc ccagcaccac
    18541 gcgtaccgct tcgctgtcgc ctaccggcgc atacaggaac agacgcatta ccacgccgaa
    18601 gatagcgatt ttgctcgccg tcgccaggaa ggtagaaacc ggcgcaggcg cgccctggta
    18661 aacgtctggc gtccacaggt ggaacggcac cagagagagt ttaaagccca gaccgacaat
    18721 catcaggcca aagcccgcca gcagcaacgg ctcgtgcagc ataccatcgc cgaggctctt
    18781 accgagcgct tcgaaagaca ggttgccgga ctgcgcatag accagcgcca tcccgaacag
    18841 caggaaagac gaggcggcgg cggagaggat ggtgtatttg atactggctt ccagcgagcg
    18901 tttctggcgg aaagcataac caatcaggcc gaacagcggc agtgagatca gttcaatacc
    18961 gaggaacagc gccgccagat ggttggcgtt cgccagcaga attcccccca ggctggcgat
    19021 taacaccagc aggtagaact cttcctggtt atcgttatag ccttccagcc acgggtaggc
    19081 aaaagtacag gtggcgaggc tcgccagcag caccagcccg gtgtagagca tcgcaaagcc
    19141 gtcaacgcgc atcagcggcg tgacgtccat tgccccggcc tggccgacaa accaaagcga
    19201 aaccagagca gcgttaagcc caatgaccga cagcgtggca ttgaggaagt gattgcgtcg
    19261 ccacgcaatg gagagcatca caaccaccac cgtcaagccg acgatcagca gcggtagcag
    19321 cgcaatcagg tgttgtggag ttattgtcat ggcgatttac ggccttgtag tagtaacgga
    19381 attaacaaac cactgctgga tgttgctcat cgcagaatgc gaggtatcca gaatcggctg
    19441 cggatagaag ccaagcagta ccagaagcac caccagcaac agaatgataa acagctcgcg
    19501 cagcgacatc cctagcagtt cctggctggc aatctggctc ttcgctttac caaagtaagc
    19561 gcgatgcagc atcgccagcg agtatacaga ggcgaatacc agcccaaagg tcgagataac
    19621 ggtaatcatc ggcaccacct ggtagctgcc gaacagaatc ataaattcgc cgacaaagtt
    19681 accggtgccc ggcataccga gcgtcgccac cgcaaagaac atggacagcg caggcaacca
    19741 cttcatcttg ccccacaggc cgcccatcat acgcatgtca cgcgtatgca gacgttcgta
    19801 caactggcca cacagaatga acagaccggc tgcggacaaa ccgtgtgcaa tcatctgaat
    19861 caccgcgccc tggtacgcca gctgactgcc ggtgtagata gcgatcagca cgaagcccat
    19921 gtgggaaacg gaggtatagg caatcaggcg cttgatgtcg tattgggtaa aggccatcca
    19981 cgcgccgtag aaaatgccga tgacgcccag ccacatggcg atgggcgcaa actccgccga
    20041 cgcgttcggg aacaatggca gggagaaacg cagcagaccg taagcggcgg ttttcagcaa
    20101 gatccccgcc aggtcgacgg aaccggcggt cggcgcctgg gagtgcgcat ccggcagcca
    20161 gccatgcagc ggaaccaccg gcattttcac cgcgaaggcg atgaagaagc ccagcatcag
    20221 cagatattcc acaccgtggg acatcggggt attcagcagc tcttcatagt tgaaggtcca
    20281 cacgctggtc gctttatagt gcacaaacac cagcgccagg atggcaatca acatcaccag
    20341 accactcgcc tgggtgtaaa tgaagaactt ggttgccgcc gtgatacgcg ttttaccgtc
    20401 agaagctttg tggccccaca gcgctatcag gaagtacatc ggcaccagca tcatttccca
    20461 gaagaagaag aacaggaaca tgtcgatggc caggaacacg ccgataacgc cgcctaagat
    20521 ccacatcagg ttgaggtgga agaagccctg atatttttcg atttctcgcc aagagcaaag
    20581 caccgccaga acgccgagca ggccggtcag caccaccatt agcagcgaca gtccgtcgag
    20641 cgccagatgg atagagatgc caaaacgcgg gatccacggc aggacaaatt cagattgcca
    20701 ctgtggaata ccggcggatt gcgtcagtga gtagccgccc tgcaaccaca attgcagacc
    20761 gagcgccagc gtcagttcca tggtaatcag cgctatccag cgcggcactt tcacgccaaa
    20821 gcgttcggtc tgccagcaca gaaagccgcc gataaagggg attaatatca accagggtaa
    20881 taacatagct aagtatgtcc cttatattta ctcctgctca ggctatctca ctcgtcagcc
    20941 caaatcctgc cagtgctcac acaaaacgca gcgcgttttg aacgtccgta aggacggccc
    21001 cgtaggggtg agcttcgcga atcatcctca cgtacttcag tacgctccgg ttgctgtgcg
    21061 ctggcggtat ccggtctgac ttcgccgatg acgcctgtac ttcaggaaca gattttcaac
    21121 gaattctaaa aattattttt gggtttgtag gccggataag cactgcgcca tccggcagtc
    21181 gttcatccag ccaacaaact caacgcagta ccatcagcag cgccagcacc acaaccgcgc
    21241 cgatgctcat ggatgccaca taccagcgca aataaccgtt ctcgctcagt accaggcctt
    21301 tgcctgcaaa acgggaaagg atagccggaa tgttcatcaa cgcattaagc gggtcgcgct
    21361 tcagcagcca ggcgataccg aggaatggct tgacgaatac tttgtcgtac agccagtcaa
    21421 agccccaggc gttataccac caggtcccca gcagatggcc cggcgcgctg ttggcgatcg
    21481 acgtcaccag cgtacgttta cccagccaca gccatgcggc aatcaggatg ccggcaatcg
    21541 ccactacgcc agaggtaatt tccagggtca acacacgacc atgcgccagt tcagttgtct
    21601 gcggcagcac cccctgcaga ggcggcacaa tcagcgcgcc aacaaaggta gacagaatca
    21661 tcaggacaat cagcggcaga tggtgggtaa tccccttccc tgcatgagca tgaatttgtt
    21721 ctttaccgtg gaatacgatg aaaatcatcc ggaaggtgta cagggaggtc atgaacgcgc
    21781 caaccagacc cgccaccatc agattgatat gaccgttcgc catcgcgcca gccaggatct
    21841 catccttact gaagaagccc gcagtgacca gcggcagcgc cgacagcgcc gcgcccccca
    21901 ccaggaagca ggcatacacc agtggaatgg acttacgcag accgcccatc ttaaagatgt
    21961 tctgttcgtg atggcaggcc aaaattaccg agccggatgc caggaacagc agcgctttaa
    22021 agaaggcgtg cgtcatcagg tggaaaatcg ccgcatccca cgcctgcacg ccaagcgcca
    22081 ggaacatgta gccaatctgg ctcatggtgg aataggccag cacgcgtttg atgtcggtct
    22141 gcaccagcgc ggcgaaaccc gccatgacca gcgtaatcgc cccgataatg cccaccagat
    22201 gcagaatttc cggggtcatc aggaacaggc catgcgtgcg tgcgatcagg tagacaccgg
    22261 cggtaaccat ggtggcggcg tggatcagcg cggagaccgg cgtcggaccg gccatcgcgt
    22321 cggcaagcca ggtctgcaac ggtagctgcg cagatttacc gaccgcgccg cccagcagca
    22381 tcagcgtcgc ccacatcagc atgttgttgc cgtcagcaaa gtgcgctggc gccagctcga
    22441 ccatttcgcg gaagttcagc gtgcccagtt cgttgtagag gatgaacagc gcgaaggcga
    22501 ggaatacgtc accgacacgg gtcaccacga aggctttcat tgccgccgcg ccattcttcg
    22561 gatcgctgta atagaagccg atcaacagat aagagcacag gcccacgcct tcccagccga
    22621 ggtacatcaa cagcaggtta tcggacagca ccagaacaac catgctggcg ataaacaggt
    22681 tggtataagc gaagaagcgg gagtagccct cttctccacg catgtaccag gaagcgaaca
    22741 tgtggatcag gaagccgacg ccggtgacca cagagagcat ggtcagcgac aggccgtcca
    22801 gcaccaggtt aaaaccgatg ttgaagttac cgaccgacat ccacgtccac agcggctggc
    22861 tgaacgcctg tttgccgttg gcgaagaaat ccatcccgac aaacgctgtc accaacgccg
    22921 ccagaccaac ggagcccacg ccaatggtcg cggagagatt ttccgaccag cgtccgcgag
    22981 agaacgccag cagtacaaag ccaatcaatg gcagaataat ggttaaggca agcatgttca
    23041 tccacgcatc tcacttactg aatcgatgtt caggttctgg cgacggcgat ggagttgcag
    23101 caacagcgca agtccaatac tcgcttccgc agccgcaagg ctgatggcga gaatgtacat
    23161 cacctgacca tcggtctggc cccagtagct cccggcgacc acaaaggcca gcgcggaggc
    23221 gttaatcatg atttccagcc cgatcagcat aaacagcaga ttgcggcgga taaccagacc
    23281 ggttaaaccc aggacgaata aaatcgcagc gaggatcagt ccgtgtgtta aggggatcat
    23341 gcgcgctcct ccgtttttct tttcgcgcgg tcatcggcgc ggttgcttag cacttcgccc
    23401 gcacgctctt cacgaccgac gtggaacgcc accaccaggc ctgccagcag cagcatagac
    23461 gccagttcga ccgccagaac ataaggcccg aacagcgtaa tgcccaccgc tttcgcgcta
    23521 atcggcgtgc cgtcgatgcc ctggtcgtta acgcccagaa tggcgtacac aataaccgcc
    23581 agcataatgg ccgacaaaac cgccggacca atccacacct gcggcttcag ccactggcgt
    23641 tcctgttcga tttcgctgcc gccgaggttg agcatcatca ccacgaacac aaacagcacc
    23701 ataatggcac ccgcgtagac gataatttcc agcgcaccgg caaagtaagc gcccagcgaa
    23761 aagaacaccc cggaaatcgc cagtagcgat atcaccagat acaacagcgc gtgtaccgga
    23821 ttggtatggg tgatcactcg cagggtcgcg aggatggcta tcaggccaca gatataaaaa
    23881 gcgaattcca ttgccctctc cttacggtaa caggctcttg acgtcgatag gcttggcttc
    23941 gttctctgct tcgcctttat ctttgccgtc gattgccata cccgccatcc ggtagaagtt
    24001 atattccggg tatttgcccg gaccggaaat cagcagatcc tctttttcgt acaccagatc
    24061 ctgacgtttg tattcgccca gttcgaagtc cggggtcaac tgaatcgccg tggtcgggca
    24121 cgcttcttcg cacaggccgc agaagatgca gcgtgagaag ttaatgcgga aaaattccgg
    24181 ataccagcgg ccatctttgg tctccgcttt ttgcagagag atacagccta ccggacaggc
    24241 taccgcgcac aggttacagg caacgcagcg ctcttcaccg tccgggtcgc gcgtgagcac
    24301 gatacggcca cggtaacggg gcggtaaata gaccggctct tccggataca tccgcgtttc
    24361 gcgtttcgcg aacgcatgca ggccgatcat ccagatactg cgtacctgag tgccgaaacc
    24421 tactaataat tcttttaagg tcatggtctt tgtgtccctt attgcgcctg ccacagaatg
    24481 acagccgccg ttaccagcaa gttgatgagc gtcagcggca ggcaaacttt ccagccgaag
    24541 gacattacct ggtcataacg cggacgcggt aacgacgcac gaatcaaaat gaacatcatc
    24601 atgaagaacg cggttttcag cgcgaaccag acgaatggcg gtaagaacgg gccatgccag
    24661 ccaccgaaga acaacgttac catcagcgcg gaaacggtga cgatgccgat gtactccccc
    24721 acgaagaaca gaccgaattt cataccggaa tattcgatgt ggtaaccgtc cgccagttcc
    24781 tgctcggctt ccggctggtc aaacgggtga cggtgacaga ccgctacgcc cgcgatggcg
    24841 aaagtaacaa acccaaagaa ttgcggaatc acgttccaca gatgcgcctg gttattgacg
    24901 atatcggtca tattaaatga accggcctgc gccaccacgc ccatcaggga aagaccaagg
    24961 aacacttcgt agctcaccgt ctgggcagac gcgcgcatcg cgcccagcag cgagtatttg
    25021 ttgttgctcg accaaccggc gaacagtacc gcgtaaaccg ccagaccggc catcatcagg
    25081 gagaacaaaa tcccgatgtt taaatcggcc accacccagt tagggctaac cggcacaatg
    25141 gcgaaggaga gcagcagcga agtaaacgcg atcatcggcg ccagggtaaa gatgacgcga
    25201 tccgagaatt tcgggatcca gtcttcttta aagaacatct tgatcatatc cgcgaccagc
    25261 tggagcgagc cgccccagcc aacgcggttt ggtccataac ggttctggaa cagacccagc
    25321 agacgacgtt cgccaaagct catgaaggcc ccgcaggtga cgaccaccag cagaatcacc
    25381 accgctttga gaatgctcag caggatctca atcagatccg gtgtaatcca actcattgtt
    25441 gcgcctcccg cagatcctca agacgcgcgc cagccagaac cggcgcgatg ccaggcatac
    25501 ccatcggcag ccctacctgc cctgccgcta acccttcaga gatttcaacc ggcagcgtca
    25561 ccgtattgcc atcgtagcta aaggagacgc gagtcccggc attgacgccc aacttcgcag
    25621 catccgccgg gttaagtttg atatacggct gcggcatacg gctctggaag accggagaac
    25681 gctgagacaa ttcgtcgctg ccaaacaggt ggtaatacgg cgcaatacgc cactgaccgt
    25741 cctgcgcctg gaagcttgcc ggcacggtag tgaaataatc cagaccgccc tcagtcgctt
    25801 caatcaaacg cacgcccgga tcgccgtgac gcagtttgcc gcccacttca tcctggaatt
    25861 tgttccacgc ctgcggagag ttccagcccg gcgcccaggc gaacggaatt tcagatcgcg
    25921 gggcagtcgg ttggttattc ccttccattg agaaggcgaa catggtgtct ttatcctgcg
    25981 gctgacgtgg ttcatgcacg ctgatattgg cgcgcatcgc cgtacgaccg ctgtaacgat
    26041 gcggttcgcg cgccagcttc tgcccacgaa tgcggaaggt cgcatccggc gcggcgtcct
    26101 taatgccggc aaattgcggc atggcggcaa tgaccgcgtc gatcacatgg tcaagctgtg
    26161 tccagtccac ttcgcggttt tcgacggtgc tgtgcagcga atgcagccag cgccagcttt
    26221 ccagcataat cgtcttgtta tcgtagtagg ccgggtcata aacctggaag aagcgctgcg
    26281 cgcggccttc gttgttgatg accgtaccat cgctttcggc gaagcttgcc gcggaaagca
    26341 ccagatgagc attttccata atcgccgtgc gctgatggtc aaccaccatc accagcggcg
    26401 ctttggcgag cgcggcgttc acgcgcgtag cgcttgcatg acggtggaga tcgttttcca
    26461 gcaccaccac cgcgtccgcg ctgccggttt ccagctcgcc caacgcatcg tcaagcgaac
    26521 cgccgcccat catacccagc cccatgctgt tcacggagcg ggcaatcata gtaataccga
    26581 cgtcggcgcc acggcctttc agcgctttcg ccacgttggc ggccgcctga atcacctcac
    26641 tgctaccggc gttagtgccg gagataatca gcggtttttt cgcgccggcc aacgcctgca
    26701 caatgacatc aattttgttt tgcaagtcgc tgtcgatacc gtcaaccgca ggcgctgtat
    26761 tgtccagcgc atgggcaatc gcaaagccca ggcgcgcctg atcttccacc ggcgcgcgat
    26821 aagtccaggc ggcgatatca tccagacggg tgtcgtccac gttagtcacg aacagcggat
    26881 gtttggcacg ctggccgatg ttaaggatgg ccgcaatctg ccagtcggcc actttctgcg
    26941 ccgccgccat ttcacgcgct ttacctttca ccgcctggcg taccgccagc gcaacgcgcg
    27001 cgccggtctg agtgacatcc tcacccaaga ccagtaccgc gtcataagat tcgatctccc
    27061 gcagcgccgg ggtgtaaatt ccgccttcac gcagcacttt cagcgccagt tgcagacgtt
    27121 cctgctcgcc gcgcgcgata ccggtgtaga agttttccgc accaaccagc tcacgcagcg
    27181 caaagttgct ctcaatgctg gcgcgtggcg aaccgatacc gatcactttc ttcgactggc
    27241 gcagaatatc cgccgcgccc tgcatcgcct gctcggcgtt gagagtaata aagtcatcgc
    27301 cacgacgctg aaccggctga cgcgggcggt ctttcaggtt cacatagcca tagccgaaac
    27361 gaccgcggtc gcagaggaag taatggttaa cggtaccgtt gtaacggttt tcgatacggc
    27421 gcagttcgcc atagcgctcg cccgggctga tgttacagcc gatggaacac tgctggcaga
    27481 tgctcggcgc aaactgcatg tcccatttac ggttgtaacg ctcggagtgc gttttatcgg
    27541 tgaagacgcc ggtcgggcaa atctcgacca ggttaccgga gaattcgctt tccagcgtac
    27601 cgtcttccgg acgcccgaag tagacgttgt catgcgcgcc atagacgccc agatcggtac
    27661 cgtcagcata atctttgtag taacgtacac aacggtagca ggcgatgcag cggttcattt
    27721 cgtgcgagat gaacggcccc agatcctggt tgcggtgggt acgtttggtg aaacggtagc
    27781 ggcggaaact gtgacccgtc atcacggtca tatcctgaag atggcagtta ccgccctctt
    27841 cacagaccgg acagtcgtgc gggtggttag tcatcagcca ctccaccacg ctttcacgga
    27901 actgtttcgc ttcttcgtcg tcaatagaga taaaggtacc gtcggtggct ggcgtcatac
    27961 aggacatcac caggcgacca cgcgtatctt ccgcgttttg gtattgcttc accgcacact
    28021 ggcggcaagc accgacgctt cccagcgccg ggtgccagca aaaatacgga atatcaaggc
    28081 cgagggacag acatgcctgt agcaggttgt ccgcgccgtt gacctcgtat tctttgccgt
    28141 ctacatgaat cgtagccatt agcatgcttc caaattaaaa atcgttaact caccagcgct
    28201 ctttgagcag gttcggctga ataccattga ttaaatgggt attactgaac ggctgcttga
    28261 tgccagcttc gaattcttcg cggaaatact taattgcgct ttgcagtggc tcaaccgcgc
    28321 ccggcgcatg cgcgcagaag gttttacccg gcccgaggaa tcgacacagt tgctcaagcg
    28381 tctcgatatc ccccggctgg ccttcgccac gctccagcgc gcgcagaatt ttcacgctcc
    28441 acggcaaccc gtcgcggcat ggcgtacacc agccgcagga ttcgcgggca aagaactctt
    28501 ccaggttacg caccagcgac accatgccga tttcgtggtc taccgccatc gccagcgcgg
    28561 tgcccagacg gctccccgct ttaccgatgc tttcgaattc catcggcaga tcgaggtgtg
    28621 cttcggtcag gaagtctgtc cccgcgccgc ccggttgcca ggctttgaat ttcaggccgt
    28681 cacgcatacc gccggcgtag tcttcgagga tctcgcgcgc gatggtgccg aacggtaatt
    28741 cccacaggcc cggattcttc acgcggcccg agaagcccat cagcttggta cccgcatctt
    28801 tgcttttcga gatgttctgg taccactcca cgccgttggc gaggattgcc gggacgttac
    28861 acaacgtttc gacgttattc acacaggtcg gcttgcccca tacgccggag gtcgccggga
    28921 aaggcggctt ggagcgcggg ttcgcgcggc ggccttcgag ggagttaatc agcgccgttt
    28981 cttcaccaca gatgtaacgc cctgccccgg tgtggacaaa cagttcgaag tcgaacccgg
    29041 tgcccatgat atttttgcca agcagcccgg cctcggttgc ttcggcaatc gcacggcgca
    29101 gatgtacagc cgcttcgata tattcgccgc gcaggaagat gtaaccacga tacgctttca
    29161 gcgcgaacgc ggagatcagc atgccttcca ccagcaggtg cggcagttgt tccatcagca
    29221 gacggtcttt ataggtgccc ggctccattt catcggcgtt acacagcagg taacggatgt
    29281 tcatggattc atctttcggc atcaggctcc acttcagacc ggtggaaaag cccgcgccgc
    29341 cgcgcccttt cagaccagcg tcttttacct ggctgacgat ttcatccgga gacaggccgg
    29401 tcagcgcctt acgcgcgcct tcgtagccgt ttttgctacg atattcatcc agccagaccg
    29461 gctgtttgtc atcgcgcaga cgccaggtca gcggatgggt ttcgggagta cggataacgt
    29521 ttttcattta taccgctcca gtagttcagg aatggcttcc ggggtcagat ggctgtgagt
    29581 atcctcatca atcatcatgt tcggcccttt atcgcaattc cccaggcagc aggtcggcag
    29641 cagcgtaaag cggccatcaa aggtcgtctg ccccggtttg atgttgagat ttttttccag
    29701 cgcggcctga atcccctgat agccggtgat atggcacacc acgctgtcgc agtagcgaat
    29761 cacgtggcga ccgaccggct gacggaagat ctggctgtag aatgtggcga cgccttcgac
    29821 gtcgctcgcc ggaataccca gcacatcggc aatagcgtag atcgcgccgt ccggcaccca
    29881 gccacgctgc ttctgaacga ttttcagcgc ttcaatggac gccgcacgcg ggtcttcgta
    29941 gtggtgcttc tcgtgctcta tcgcttcacg ctctgccgca ctcagctcaa aagcctcggt
    30001 ttgtggttgt tgattctcgt gcataattag cggtccacat ctgacataac aaaatcgata
    30061 ctacccagat agacaatcag gtcggagacc aggctaccgc ggatcgccga gggaatctgc
    30121 tgcaggtgcg caaagctcgg cgtgcgcacg cgggtacggt agctcatagt gctgccgtcg
    30181 ctggtcaggt agtaactgtt aatccccttc gtcgcttcca ccatctggaa ggactcctgc
    30241 gccggcatca ccgggcccca ggagacctgc aggaagtggg tgatcagggt ttcgatatgt
    30301 tgcagcgtgc gctctttcgg cggcggcgtg gtcagcgggt gatccgcttt gaacggccct
    30361 tccggcatgt tatcgaggca ctgctgaaga atgcgcagac tctggcgcag ctcttccact
    30421 ttcagcatca cgcgggtata gcagtcggaa acgccgccgc ccaccggcac ttcaaagtca
    30481 aagttttcgt agccagaata tggacgccat ttacgcacgt cgaagtctat cccggtcgcg
    30541 cgcagccctg cgccggtggt gccccactcc agcgcctctt tcgcgccgta agcggcaacg
    30601 ccctgcgaac gccctttcag aatggtgtta cgcagcgcgg ctttctcgta agagtccaga
    30661 cgcttcggca tccactcaag gaactctcgc agcaggcgat cccaaccgcg cggcaagtcg
    30721 tgcgcgacgc cgccgatacg gaaccaggcc gggtgcatac ggaaaccggt aatggcttcc
    30781 accagatcat aaattttctg ccggtcggta aaggcaaaga agaccggggt catcgcgccg
    30841 acgtcctgaa taaaggtcga aatgtacagc agatgactgt taatgcggaa cagttcggag
    30901 agcatcacgc ggatgacgtt cacacgatcc gggacggtga tccccgccag tttttctacc
    30961 gccagcacgt acggcatttc attgacgcaa ccaccgaggt attcgatacg gtcggtatag
    31021 ggaatgtagc tatgccagga ctggcgctcg cccatttttt cggcgccgcg gtggtgatag
    31081 ccgatatccg gcacgcagtc gacgatttct tcgccgtcaa gttgcaggat aatacgaaac
    31141 gcaccgtgcg cagacgggtg gttcgggccg aggttgagga acataaagtc ctcgttgtca
    31201 gtcccgcgct tcatccccca gtcttccggc ttaaaggtca acgcttccat ctccagatcc
    31261 tgcttggctt tggtcagctc aaacgggtcg aattcggtcg cgcgcgccgg ataatcttta
    31321 cgcagcggat ggccttccca ggtttgcggc atcatgatgc gcgtcaggtg cgggtggcct
    31381 tcgatatcaa tgccaaacat ctcccaggtc tcacgctcgt accagttggc gttagggaaa
    31441 agtttagtga aggtcggcac gcgcaggtcg ttttcagaca acgccacctt gagcataata
    31501 tcgcgattac gctcaatgga aatcaggtgg tagaaaacgg aaaaatccgc ggcgggtaac
    31561 ccgtcacggt gcgtacgcag gcgttcatcc atgccgtgta agtcaaacag catgacgtaa
    31621 ggtttcggca gtttctttaa gaaatcgcca acctccagta gttgttcacg cttgacccaa
    31681 acaacgggga taccggtgcg ggtcgcctga acggtaaagg catccggccc aaaacggttg
    31741 cgcagttcgc cgataaccgg atcatcaaga tgatcgcggg tactccatgc agcgtcttgc
    31801 gcggttaagt cggtcatatt gttcaccatt gcaaatggtc cgtggtggtc ggcagtgctt
    31861 cgcgctatta aaatagtggt tagcgaagtg aagtgctgct gccgacaggc gcaaattaaa
    31921 tctcgtccgg ggtacgcagg ttcgtgacgg caatacgctc gccgcgttta cgttcgcgtt
    31981 ctggctgcat attggcgcga tacacgccct gatcgcccac cacccatgag agcggacggc
    32041 gctctttgcc aatcgattct tgcagcagca tcaacgcttg catatacgct tccggacgcg
    32101 gcggacagcc agggatatac acatccaccg ggataaactt atcaacgccc tgcactaccg
    32161 aataaatatc gtacatgccg ccggagttgg cgcaggcgcc catagaaatg acccattttg
    32221 gctccagcat ttggtcatac agacgctgaa taaccggagc cattttggta aagcaggtac
    32281 cggccaccac catcagatca gcctgacgtg gcgacgcacg cagcacttcc gcgccgaaac
    32341 gggcaacgtc atgcactgcg gtaaacgagg tcaccatctc tacatagcag caagaaaggc
    32401 cgaagttgta gggccaaatt gagtttttac ggccccagtt aaccatgtca tgcagtttgc
    32461 ccatgaacac gtttttgtta acttcctgct ccagggggtc ggttacgatc tcctgttttt
    32521 gcagggggta acggtcattc tcaccgttag gatctatgcg ggtgagcgta taatccatct
    32581 taatgcctcg cggttagcgt tgacgattag cgatactgtt cgtttccggg ttcatacgct
    32641 cgcggcgtga acgcgcgggc gtccagtcca acgcgccaat acgcgccaga taaaccagac
    32701 cagccagtaa cacaaaaata aaaattgcag cttccacaaa gccaacccag ccgctttcgc
    32761 ggatagaagt tgaccatgcg aacagataca gcgcttcaac gtcgaagata acgaagaaca
    32821 tggctaccag gtaaaacttg gcagacaagc gtaagcgggc ggtgccgacc gagtcgatac
    32881 ctgattcaaa cggaacgttc ttgtgcctcg cgcgtgcgcg accgcccaaa aaccaaccgc
    32941 ctaccagcat caggcagcac aggccaatgg caacgataag aaagatagcg aatgcccagt
    33001 gatgagcgat gacttcagtg gatgttgaca tactcattgc ttactcatca aaagtagcgc
    33061 cagttcctct gctctttacg gcagatggac gccacatcga ttcaggggag gaataaaaaa
    33121 accctacaat tactgtagaa aatgataaaa acagctaatt gatgtggttt tttactcctt
    33181 tctataacct tttgtcaact ttaacaaaag ttccttcaca ttaatttaca tcaattcatc
    33241 atcattaaca ttaagtgcca tcctggagaa aatgactctt cgaccagggg ggattttatg
    33301 ttgttgaatc gtgtccgttg tgaagcaaaa gaaataacac acacctattt tgacaggaat
    33361 ttgtgaagat gcctccccct aaatgggagt attttcttga tctgtgacac gcttttgtta
    33421 attcaccccc taaaacagca acaatttctc tagtttttta acatgcaaat tcataaaatg
    33481 gatgttctgg ttattttttg cccacattga actgcgaatc gctactggct gatttaccgc
    33541 aacttttaca atttgtgcgg ttaagcgcgt acagatgggc acaaaaaaag agccactgag
    33601 cgttttttca tcgccagcgg ctctttttta catttacgac ttagcgcctt ttgcctgcga
    33661 gctactcaaa acccccttcc accatcagcg gatcatctcc gccctctgca gaaaactggt
    33721 tgtaatgcca tgggttttga tagctttcca tcgcatggaa aatcaccatc gccagctcgt
    33781 tctggctatt gggatcgcgg cacaacatat attccgtatc cagcaaaggc ggtaatccat
    33841 ctgcggcgcc cagcacgcga aggtcgggac tcatcatttc gacaggtcga gccgttacgc
    33901 caagaccggc tttaacggcc gcgcgtaccg ccagtaatgt agaggccaca taggccagcc
    33961 gccagggaat acccgctgca tttagcgtct ccagcaccat atcgcggaat gggctgggat
    34021 cgtccagcag gactaatggt acgggctctc ccctttgcaa aacatactca gccgcacaat
    34081 accaatgggt gggcgaggtc cgcaaattca gacagtccag cgaatgaggt tggttagtcg
    34141 tcaccaccaa atctacttcc tgcgatttaa ccatgtccac catataggcg ttgcgtttta
    34201 cccgtacatc aagcgcgagt ttcggataaa ccgagctgat tcggctaagc aaaaaaggca
    34261 ggatagtatc agctgattca tcagaagcgc cgattgttaa cactccctga agattactga
    34321 acattaatga tgaacacgcc tcatcattaa aacgcaggat ttttctggcg taccccagaa
    34381 gctggatacc gtgttcgctc aaaagtttgt tacgaccatg gcgggcgaac aattcctttc
    34441 ccacgagttg ctcaagacgc tgcatttgct gactgaccgc agactgagta cgacataccg
    34501 ccgccgccgc cgcggcgaag gtgttcagat cggcaacggc cacgaacgtt ctcagcagat
    34561 cgagatcgag gttaattatc ggacgatttg catttatcat aatttttcac ttactgacgg
    34621 gtcatatcgg gctgacctgg ttaatgctgt gcattcagaa acaagcaatt ccatttgtaa
    34681 tgtgcatcct tcgcagtacc gcctggttac ccaggtaaat gttagaatgt aattgaaaat
    34741 acgaccaaaa cacttctctt acttactgat ataataccaa atgcaactga tcgggatata
    34801 tcaaagagaa tgtgtcatac ctttaggcgt ctacagattt ctgctaatga tggacgtgta
    34861 aatcttg
//
LOCUS       DAJVKX010000037        34799 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000037 DAJVKX010000000
VERSION     DAJVKX010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 34799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34799
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.037"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..111
                     /locus_tag="OPY25_001806"
     CDS             <1..111
                     /locus_tag="OPY25_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927437.1"
                     /translation="TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            175..813
                     /locus_tag="OPY25_001807"
     CDS             175..813
                     /locus_tag="OPY25_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HCS0927438.1"
                     /translation="MKRLALILICLLLQACSATTKGLGDSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFSENGQQKWVTQDGATIVTQHGRLVKTLLGGDNLI
                     DVNNLATDPLAKPGQIIDGATWTRTLGWTEHRQVRYATARSVFTWRGTDRVNVGSEET
                     AVRVLDEEVTTDQTRWRNRYWVDSEGQIRQTEQYLGANYFPVKTTLIKAAKS"
     gene            810..1544
                     /locus_tag="OPY25_001808"
     CDS             810..1544
                     /locus_tag="OPY25_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HCS0927439.1"
                     /translation="MMKRTISALALAFVASSAFASGTVTVFTQGNSEPKTLTDAERLL
                     DLVGQPRLATSWWPAAVIGEEQATVTARQQQQELLGRLAALSAEEDGDAAAINTLRRQ
                     IQAVKVTGRQFVNLDPDVVRVSERGNPPLQGHYTLWVGPQPTQVTLFGLISQPGSQPF
                     VPGRDVASYLEGQRLLSGADRSYAWVVYPDGRSQKAPVAYWNKRHIEPMPGSIIFVGF
                     ADSLWRGTPEAINADILHTLTQRIPE"
     gene            1544..3640
                     /locus_tag="OPY25_001809"
     CDS             1544..3640
                     /locus_tag="OPY25_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HCS0927440.1"
                     /translation="MKKTHLLSVLALGISAACHAETYPAPVGPSQSDFGGVGLLQTPT
                     ARMAREGEMSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTKKYSSVESFSGDQTY
                     KDKAFDVKLRLWEESYWMPQVAVGARDIGGTGLFDAEYIVASKAWGPFDFSLGLGWGY
                     LGTSGNVSNPFCSYSDKFCSRDNSYKEAGSVDGSDMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYCVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPAYHDNSRPQYRPQPQDAILQHSVVANQLTLLKYNAGLADPKIQVKGDTLYVTGE
                     QVKYRDSREGIVRANRIVMNDLPEGIRTIRVTENRLNLPQVTTETDVASLKRHLEGEP
                     LGHETPLAQKRVEPIVPESTEQGWYIDKSRIDFHLDPVLNQSVGGPENFYMYQLGVMG
                     TADLWVTDHLLTTGSVFANIANNYDKFNYTNPPKDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQYFGNGFYGQVYGGYLETMFGGAGAEVLYRPVDSNWAFGLDANYVKQRDWRSA
                     QDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITDASPDEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFGLYDMTSDRSVNFR"
     gene            3783..4193
                     /gene="psiE"
                     /locus_tag="OPY25_001810"
     CDS             3783..4193
                     /gene="psiE"
                     /locus_tag="OPY25_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HCS0927441.1"
                     /translation="MMPLSRSRLEFIATILQNVLNLGLLTLGLILVVFLGKETVHLAD
                     ALFAPEQASKYELVEGLVIYFLYFEFIALIVKYFKSGLHFPLRYFVYIGITAIVRLII
                     VDHKTPMDVLLYSAAILLLVITLWLCNSNRLRRE"
     gene            complement(4359..5249)
                     /gene="malG"
                     /locus_tag="OPY25_001811"
     CDS             complement(4359..5249)
                     /gene="malG"
                     /locus_tag="OPY25_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HCS0927442.1"
                     /translation="MAMVQPKSQKLRLFITHLGLLIFIAAIMFPLLMVIAISLREGNF
                     ATGSLIPDKISWEHWRLALGFSVEHADGRVTPPPFPVLLWLWNSVKIAGITAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVDSYTLAVGMQQYLNPQNYLWGDFAAAAVLSAIPITL
                     VFLLAQRWLVNGLTAGGVKG"
     gene            complement(5264..6808)
                     /gene="malF"
                     /locus_tag="OPY25_001812"
     CDS             complement(5264..6808)
                     /gene="malF"
                     /locus_tag="OPY25_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HCS0927443.1"
                     /translation="MDVIKKKHWWQSDQLKWSVIGLLGLLVGYLVVLMYVQGEYLFAI
                     MTLILSSAGLYIFANRKTYAWRYVYPGLAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQQVLMDRSYQAGKTYNFGLYPAGDEWQLALTDGETGKHYLSGAFSFGGEQKLQLK
                     ETDALPGGERANLRIITQNRLALNQITAVLPDESKVVMSSLRQFSGTRPLYTLADDGL
                     LTNNQSGVKYRPNNDSGYYQSINADGSWGDEKLSPGYTVTIGAKNFTRVFTDEGIQKP
                     FFAIFVWTVVFSVLTVVLTVAVGMVLACLVQWEALKGKAIYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGIKPAWFSDPNTARAMVIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVSYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            complement(6940..8130)
                     /gene="malE"
                     /locus_tag="OPY25_001813"
     CDS             complement(6940..8130)
                     /gene="malE"
                     /locus_tag="OPY25_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HCS0927444.1"
                     /translation="MKIKTGVGILALSALTTMMISAPALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEQDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEVTPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLVPNPPKTWEEIPA
                     LDKELKAKGKSAIMFNLQEPYFTWPLIAADGGYAFKFENGKYDVKDVGVDNAGAKAGL
                     TFLIDMIKNKNMSADTDYSIAEAAFNKGETAMTINGPWAWSNIDKSKVNYGVTLLPTF
                     KGKPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDQGLEAVNKDKPLGAVALKSFQ
                     EQLAKDPRIAATMDNAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALKDAQS
                     RITK"
     gene            8492..9601
                     /gene="malK"
                     /locus_tag="OPY25_001814"
     CDS             8492..9601
                     /gene="malK"
                     /locus_tag="OPY25_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HCS0927445.1"
                     /translation="MASVQLRNVTKAWGDVVVSKDINLDIHDGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGETRMNDIPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVMNQRVNQVAEVLQLAHLLERKPKALSGGQRQRVAIGRTLVAEPRVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIEQVQVELPNRQQIWLPVESRGVQVG
                     ANMSLGIRPEHLLPSDIADVTLEGEVQVVEQLGHETQIHIQIPAIRQNLVYRQNDVVL
                     VEEGATFAIGLPPERCHLFREDGSACRRLHQEPGV"
     gene            9690..11048
                     /locus_tag="OPY25_001815"
     CDS             9690..11048
                     /locus_tag="OPY25_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin"
                     /protein_id="HCS0927446.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQVTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVNQQNDWEST
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGIENIDLG
                     FGKLSLAATRSTEAGGSYTFSSQNIYDEVKDTANDVFDVRLAGLQTNPDGVLELGVDY
                     GRANTTDGYKLADGASKDGWMFTAEHTQSMLKGYNKFVVQYATDAMTTQGKGQARGSD
                     GSSSFTEELPDGTKINYANKVINNNGDMWRILDHGAISLGDKWDLMYVGMYQNIDWDN
                     NLGTEWWTVGVRPMYKWTPIMSTLLEVGYDNVKSQQTGDRNNQYKITLAQQWQAGDSI
                     WSRPAIRIFATYAKWDEKWGYIKDGDNISRYAAATNSGISTNSRGDSDEWTFGAQMEI
                     WW"
     gene            11212..12129
                     /gene="malM"
                     /locus_tag="OPY25_001816"
     CDS             11212..12129
                     /gene="malM"
                     /locus_tag="OPY25_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HCS0927447.1"
                     /translation="MKMKKSLVALCLTAGLFASVPGISLAEVNYVPQNTSAAPAIPAA
                     ALQQLTWTPVDQSKTQSTQLATGGQRLDVAGITGPVAAYSVPANIGELTLTLTSEVNK
                     QASVFAPNVLILDQNMTPSAFFPSSYFTYQQPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTTLLDPAKAYAKGVGNSIPDIPDPVARHTTDGVVKLKVKTNSSSSVL
                     VGPLFGSSGTGPVTVGNTAAPVAAPAPVAPKKSEPMLNDTESYFNKAIKDAVAKGDVD
                     KALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            12310..12807
                     /gene="ubiC"
                     /locus_tag="OPY25_001817"
     CDS             12310..12807
                     /gene="ubiC"
                     /locus_tag="OPY25_001817"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HCS0927448.1"
                     /translation="MSHPALTQLRALRYFDAIPALEPHLLDWLLLEDSVTKRFEQQGK
                     RVSVTLIREAFVGQSEVEEASGLLPSESRYWLREILLCADGEPWLAGRTVVPESTLCG
                     PEQVLQHLGKTPLGRYLFTSSTLTRDFIEIGRDATLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            12821..13693
                     /gene="ubiA"
                     /locus_tag="OPY25_001818"
     CDS             12821..13693
                     /gene="ubiA"
                     /locus_tag="OPY25_001818"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HCS0927449.1"
                     /translation="MEWSLTQSKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGMP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTVNRPLPSGAVTEKEARNLFVV
                     LVLLAFLLVLTLNAMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDIKIGIKSTAILFGRYDTLIIGIL
                     QLGVMALMALIGWLNGLGWGYYWAVLVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(13792..16212)
                     /gene="plsB"
                     /locus_tag="OPY25_001819"
     CDS             complement(13792..16212)
                     /gene="plsB"
                     /locus_tag="OPY25_001819"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HCS0927450.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLPRYVFIHGGPRVFTYYTPKEESV
                     KLFHDYLDLHRSNPALDVQMVPVSVMFGRAPGREKGEENPPLRMLNGVQKFFAISWLG
                     RDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASKAIARAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFAEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLKGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPEWRESIDPIEAIRPAWLTPTVNSI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLDCYLDLMRNVPYSTDST
                     VPAASAGELIAHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLIMPSLMA
                     AIITQHRRISRDALQQHVEALYPMLKAELFLRWEREELASVIDALASEMQRQGLITLQ
                     DDELHINPTHSRTLQLLAAGARETLQRYAITFWLLSANPSINRSTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAETMKIYQMLADLITSDVRLT
                     IESATQGE"
     gene            16383..16751
                     /locus_tag="OPY25_001820"
     CDS             16383..16751
                     /locus_tag="OPY25_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCS0927451.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGFRAAWTHEAAFRQESLAVLLGVI
                     IACWLDVDAITRVLLIGSVLLIMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LLSIFVALMTWGILLWSHFR"
     gene            16860..17468
                     /gene="lexA"
                     /locus_tag="OPY25_001821"
     CDS             16860..17468
                     /gene="lexA"
                     /locus_tag="OPY25_001821"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HCS0927452.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVLEIVSGASRGIRLLQEEEDGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPSADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFTPIVVDLREQSFTIEGLAVGVIRNGEWL"
     gene            17647..18972
                     /gene="dinF"
                     /locus_tag="OPY25_001822"
     CDS             17647..18972
                     /gene="dinF"
                     /locus_tag="OPY25_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HCS0927453.1"
                     /translation="MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVF
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLALGAGVM
                     IVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILKIALDLWLVMGLHMNVQGAALATVIAEYVTLLIGLMMVRKVLHLRGV
                     SLDMLKQAWRGNVRRLLALNRDIMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALLFSTVYALAGE
                     HIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAG
                     GFALTLFALPVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS"
     gene            18969..19082
                     /locus_tag="OPY25_001823"
     CDS             18969..19082
                     /locus_tag="OPY25_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927454.1"
                     /translation="MMVKNSEYKTEGRIPAYNYYHVQQKLQCIWANNTCYS"
     gene            19104..19313
                     /locus_tag="OPY25_001824"
     CDS             19104..19313
                     /locus_tag="OPY25_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCS0927455.1"
                     /translation="MNKDEAGGNWKQFKGKMKEQWGKLTDDDMTVIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVVDWETRNNYRW"
     gene            complement(19413..19928)
                     /gene="zur"
                     /locus_tag="OPY25_001825"
     CDS             complement(19413..19928)
                     /gene="zur"
                     /locus_tag="OPY25_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HCS0927456.1"
                     /translation="MEKTTTQELLAQAEKLCAQRNVRLTPQRLEVLRLMSLQQGAISA
                     YDLLDLLRETEPQAKPPTIYRALDFLLEQGFVHKVESTNSYVVCHLFDQPTHSSAMFI
                     CDRCGVVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCPACVEVEACRHPGDCGH
                     DHSVLVKKKPR"
     gene            20175..21485
                     /locus_tag="OPY25_001826"
     CDS             20175..21485
                     /locus_tag="OPY25_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HCS0927457.1"
                     /translation="MNKNVKLSLIAIAVSLFMTKQAGAANTWTEARNDAMGGTGVASA
                     NYGSGVLLNPALLAKAKPEDNITVVLPAVGVQITDKDNLQDEIDDISDKVDYYDEVVD
                     NLTLGQILLNPRGVLNQFQGAARDLADELEYLNGKTARANAGAGLAVSIPGQTLSVAF
                     IAKGYAHGRVSSSIDQNDIQYLRDIQHDERVALREAGRAALLGSDEITKHLNSTALGR
                     VAIVSDYGIALAKQFVVGEVPVSIGVTPKLQKTWLYNYTTSIYNYDSSDWNSSRYRND
                     DTGFNIDAGLAADIGENWTLGLSGQNLVSRDIDTKDIYITNGMTGETTNYKETYQIRP
                     LVTAGIAWHNDLLTVSADGDLTETKGFKSEDNSQYVGVGAEVRPLSWLAVRAGYRADV
                     KNNDSNVVTGGLGFAPFNRAHLDLMGLYGEDETWGAGAQLTMTF"
     gene            21573..22571
                     /gene="dusA"
                     /locus_tag="OPY25_001827"
     CDS             21573..22571
                     /gene="dusA"
                     /locus_tag="OPY25_001827"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HCS0927458.1"
                     /translation="MQPETQSSALPAYRFSIAPMLDWTDRHCRYFLRLLSRQTLLYTE
                     MVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAQLAHCAKLAEARGYDEINLNVGCP
                     SDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYAFLCDFINT
                     VSGQGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKS
                     LEEAKEHLRHMDGVMVGREAYQNPGILAAVDREIFGADTTDTDPVAVVRAMYPYIERE
                     LSQGAYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADAAVLEQALKLIADKR"
     gene            22739..22981
                     /gene="pspG"
                     /locus_tag="OPY25_001828"
     CDS             22739..22981
                     /gene="pspG"
                     /locus_tag="OPY25_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HCS0927459.1"
                     /translation="MLELLFVLGFFLMLMVTGVSLLGILAALVVATAVMFLGGMFALM
                     IKLLPWLLLAVAVVWVIKAVKTPKIPQYQRNNRRFY"
     gene            complement(23156..24139)
                     /locus_tag="OPY25_001829"
     CDS             complement(23156..24139)
                     /locus_tag="OPY25_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HCS0927460.1"
                     /translation="MATRIEFHKHGGPEVLQTVEFTPTEPAEHEIQVENKAIGINFID
                     TYIRSGLYPPPSLPAGLGTEAAGVVSKVGSGVEHIRVGDRVVYAQSTLGAYSSVHNVP
                     ADKAAILPDAISFEQAAASFLKGLTVFYLLRKTYEVKPDEPFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGSAQKAQRALDAGAWQVINYREESIVERVKEITGGKKVRVVYDSVG
                     KDTWEASLDCLQRRGLMVSFGNASGPVTGVNLGILNQKGSLYATRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAENQRYALKDARRAHEVLESRATQGSSLLIP"
     gene            24204..25619
                     /gene="dnaB"
                     /locus_tag="OPY25_001830"
     CDS             24204..25619
                     /gene="dnaB"
                     /locus_tag="OPY25_001830"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCS0927461.1"
                     /translation="MAGNKPFNKPQTDARDRDPQVAGIKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVAEDFYTRPHRHIFTEMGRLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVRDMIAVAHEIADAGYDPQGRNSDELLDL
                     AESRVFQIAENRANKDEGPKSIDQILDATVARIEQLFQQPHDGVTGVDTGYQDLNKKT
                     AGLQRSDLIIVAARPSMGKTTFAMNLCENAAMLQDKPVLIFSLEMPGEQIMMRMLASL
                     SRVDQTRIRTGQLDDEDWARISGTMGILLEKRNMYIDDSSGLTPTEVRSRARRIFREH
                     GGLSLIMIDYLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            25651..26730
                     /gene="alr"
                     /locus_tag="OPY25_001831"
     CDS             25651..26730
                     /gene="alr"
                     /locus_tag="OPY25_001831"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCS0927462.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITQPILLLEGFFDAADLPTISAQCLHTAVHNQ
                     EQLAALEAVELAEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLTHCKNVRQPVNIVSHF
                     ARADEPECGATEHQLDIFNAFCQGKPGQRSIAASGGILLWPQSHFDWARPGIILYGVS
                     PLEHKPWGPDFGFQPVMSLTSSLIAVRDHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPNAQDNAGDPVVLWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYID"
     gene            26916..28109
                     /gene="tyrB"
                     /locus_tag="OPY25_001832"
     CDS             26916..28109
                     /gene="tyrB"
                     /locus_tag="OPY25_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HCS0927463.1"
                     /translation="MFQKVDAYAGDPILSLMERFKDDSRHDKVNLSIGLYYNEDGIIP
                     QLKTVAEAEARLNAQPHGASLYLPMEGLNTYRHTIAPLLFGADHPVLQQQRVATIQTL
                     GGSGALKVGADFLKRYFPDAGVWVSDPTWENHIAIFAGAGFEVSTYPWYDDATNGIRF
                     NDLLATLNTLPARSIVLLHPCCHNPTGADLTPSQWDAVIEIVKARDLIPFLDIAYQGF
                     GAGMDEDAYAIRAIASAGLPALVSNSFSKIFSLYGECVGGLSVVCEDAEIAARVLGQL
                     KATVRRIYSSPPCFGAQVVATVLGDEALKASWLAEVDAMRTRIISMRQTLVKELKAEM
                     PDRNFDYLLQQRGMFSYTGLSAEQVDRLRDEFGVYLIASGRMCVAGLNASNVHRVAKA
                     FAAVM"
     gene            28296..29009
                     /gene="aphA"
                     /locus_tag="OPY25_001833"
     CDS             28296..29009
                     /gene="aphA"
                     /locus_tag="OPY25_001833"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HCS0927464.1"
                     /translation="MKKITLALSAVCLLFTLNHSANALVSSPSTLNPGTNVAKLAEQA
                     PVHWVSVAQIENSLTGRPPMAVGFDIDDTVLFSSPGFWRGKKTYSPDSDDYLKNPAFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDSIYFVTGRSQTKTETVSKTLADNFHIPAA
                     NMNPVIFAGDKPGQNTKVQWLQEKNMRIFYGDSDNDITAARDCGIRGIRILRAANSTY
                     KPLPQAGAFGEEVIVNSEY"
     gene            29138..29554
                     /locus_tag="OPY25_001834"
     CDS             29138..29554
                     /locus_tag="OPY25_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HCS0927465.1"
                     /translation="MWYQRTITLSEKPRGFHLITDEITDKLSGLPPVETGLLHLLLLH
                     TSASLTLNENCDPTVRADMERHFLKTVPDNAAYEHDYEGADDMPSHIKSSVLGVSLLL
                     PVRQGRLQLGTWQGIWLGEHRIHGGPRKIIATLQGE"
     gene            29557..29913
                     /locus_tag="OPY25_001835"
     CDS             29557..29913
                     /locus_tag="OPY25_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCS0927466.1"
                     /translation="MTISELLQYCMAKPGAEQSVHSDWKATQIKVEDVLFAMVKEVDG
                     RPAASLKTSPELAELLRQQHSDVRSSRHLNKAHWSTVYLDGSLPDSQLYYLVDASYQQ
                     AVNALSEDKRKQLPQS"
     gene            complement(29914..30252)
                     /locus_tag="OPY25_001836"
     CDS             complement(29914..30252)
                     /locus_tag="OPY25_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927467.1"
                     /translation="MASINEIRNLFTAARAEHPVASSAIAEFIQTYKQAREDSDDGIR
                     ESAAFIARALQEHARGWLDDDDMIILLEGQRDLARLRANNAQIALGSRIRSTVIHLID
                     IALALLVGAL"
     gene            complement(30239..30694)
                     /locus_tag="OPY25_001837"
     CDS             complement(30239..30694)
                     /locus_tag="OPY25_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927468.1"
                     /translation="MENTMKLPYAITLLLCLFLAACTLPDRFSAVAFQQLTLLQARST
                     RFLQDAARIPWQKETLLKDDRDIRQTFFQAERVARQGGDKHRLDNLALLKNHYLRLYA
                     RVMKCKQPLTYIQAERYQQQNNQVWKLAIQGECLHWGARCTQGEENGVY"
     gene            complement(30826..33651)
                     /gene="uvrA"
                     /locus_tag="OPY25_001838"
     CDS             complement(30826..33651)
                     /gene="uvrA"
                     /locus_tag="OPY25_001838"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCS0927469.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVIDRFKVRNDLSQRLA
                     ESFETALELSGGTAVVADMDDEKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPDLSLAGGAIRGWDRRNFYYFQMLKSLAEHYKFDVDA
                     PWASLSANVHKVVLYGSGKENIEFKYMNDRGDTSVRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLNREARHVFVENTPLPAISDMSIGHAMDFFTNLKLSG
                     QRAKIAEKVLKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRNLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKQRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRSRGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHQLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVAGTPETVAECEASHTARFLKPMLK"
     gene            33899..34429
                     /gene="ssb1"
                     /locus_tag="OPY25_001839"
     CDS             33899..34429
                     /gene="ssb1"
                     /locus_tag="OPY25_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HCS0927470.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPSGGAVANLTLATSESWRDK
                     QTGEMKEQTEWHRVVMFGKLAEVAGEYLRKGSQVYIEGQLRTRKWTDQSGQERYTTEI
                     NVPQIGGVMQMLGGRQGGGAPAGGQQQGGWGQPQQPQQPQGGNQFSGGAQSRPQQSAP
                     APSNEPPMDFDDDIPF"
BASE COUNT         7893 a         9007 c         9733 g         8166 t
ORIGIN      
        1 accagcgtta gcaccgtaag ttcggcggtg ggcgtcgcgt tagcggcaac cggcggcggc
       61 gatggttcca ataccggaac cacgaccacc acgaccacca gtacccagta gtatcggtac
      121 gtttaaccat aaccacactc cggtgtggtt attttgcccc tctggagaag cgtcgtgaag
      181 cgactcgcac ttatcctgat ttgcctgcta ttacaggcgt gttcggccac caccaaaggc
      241 ctgggcgatt cactgtggga cagtttgttc ggtacgccag gcgtacagct aacggatgac
      301 gatattcaaa acatgcctta tgccagccag tacatgcagc ttaacggcgg tcctcaactg
      361 tttgtggtgc tcgctttctc ggaaaacggg cagcagaaat gggtgacgca ggatggcgcg
      421 acgatcgtga cgcagcatgg ccgtctggtc aaaacgctgc tcggcggcga caacctgatc
      481 gatgtgaata atctggcgac cgacccgctg gcgaaaccag gacagattat cgatggcgcg
      541 acctggactc gcaccctggg ctggaccgaa catcgccagg tgcgttacgc caccgcccgt
      601 tccgttttta catggcgagg gaccgataga gtgaacgtcg gcagtgagga aaccgccgtg
      661 cgggtgttag atgaagaagt gacgaccgat caaacgcgct ggcgtaatcg ctactgggtt
      721 gatagcgaag gccaaattcg ccagacggaa cagtatctgg gcgcgaatta ctttccggtg
      781 aaaaccacgc tgattaaggc ggcaaaatca tgatgaaaag gacgataagc gcgctggcgc
      841 tggcctttgt cgcgtcatcc gcctttgcca gcggcactgt taccgttttt acccagggta
      901 atagcgagcc taaaacgctg acagacgctg agcgtctgct cgatttagtc ggacagccgc
      961 gcctggcaac gagctggtgg cctgcggcgg tgataggcga agaacaggcg accgtgacgg
     1021 cgcgtcagca gcagcaggaa cttctcgggc gactggcggc gctcagcgct gaggaagatg
     1081 gcgatgcggc ggcgataaac acactacgcc gacagattca ggcggtgaag gtgacgggca
     1141 gacaattcgt gaatcttgat cctgacgtgg tgcgggtgag cgaacgaggt aacccgccgc
     1201 tgcaaggtca ctacacgctc tgggtcgggc cgcaacccac gcaggtgacg ctctttggct
     1261 tgattagcca gccgggcagc cagccgttcg tccctgggcg ggacgtcgcc agttatcttg
     1321 aggggcagcg cttactcagc ggcgcggatc gtagctatgc ctgggtggtt taccctgatg
     1381 gacgcagcca aaaagcgccg gtggcttact ggaataaacg tcatatcgag ccgatgcccg
     1441 gcagcatcat ttttgtcggt tttgccgatt ccctttggcg cggcacgccg gaggcgataa
     1501 atgccgacat tcttcatacc ctgacgcagc ggataccgga ataatgaaaa aaacacatct
     1561 gctcagcgtg ctggcgctgg gtattagcgc ggcctgccat gccgaaacat atccagcccc
     1621 tgttgggcct tcacaatctg actttggcgg cgtgggcctg ctgcaaacgc cgacagcgcg
     1681 tatggcgcgt gaaggggaga tgagcctgaa ctatcgcgat aacgatcagt accgctacta
     1741 ctcggcttcg gttcagcttt tcccgtggct ggaaaccacg ttgcgctata ccgatgtccg
     1801 tacgaaaaag tacagcagcg tggaatcatt ctccggcgac cagacttaca aagataaagc
     1861 gtttgatgtg aaactgcggt tgtgggaaga gagttactgg atgccgcagg tggcggttgg
     1921 cgcgcgcgat atcggcggga cggggctgtt tgatgcggaa tatattgtag cgagtaaggc
     1981 ttgggggcca tttgattttt cattaggtct cggctggggc tatcttggca ccagcggcaa
     2041 tgtgtctaat cctttctgtt cgtatagtga taaattctgt tcgcgtgata acagctataa
     2101 agaggccggt tccgtcgacg gtagcgatat gtttcacggc ccggcttcgc tgtttggcgg
     2161 cgtggaatac cagaccccgt ggcaaccgct acgcctgaag ctggagtatg aaggcaataa
     2221 ctatcagcag gattttgcgg ggaaactgga acagaagagc aagtttaacg tcggcgccat
     2281 ttactgcgtc accgattggg ccgacgttaa cctcagctac gagcgcggca acacctttat
     2341 gtttggcgtt acgctgcgca ccaatttcaa cgatttacgt cccgcgtatc atgacaattc
     2401 acgcccgcaa taccgaccac agccgcagga tgccatcctg caacattcgg tagtggctaa
     2461 tcaattaacg ttattgaaat ataatgccgg tctggcggac ccgaaaatcc aggtcaaagg
     2521 cgatacgcta tacgttaccg gtgaacaggt gaagtaccgc gactcccgtg aggggatcgt
     2581 gcgcgctaac cggatcgtca tgaacgatct gccggagggg atccgcacga tccgcgtgac
     2641 ggaaaaccgc cttaatctgc cgcaggtcac cactgaaacc gatgtcgcca gcctgaaacg
     2701 ccatctggaa ggcgaaccgc tgggacatga aactccgctg gcgcaaaaac gcgtggagcc
     2761 gatcgtgcca gagagtactg aacagggttg gtatatcgac aagtcgcgca ttgattttca
     2821 tcttgatccc gtgctgaatc agtcggtagg cggcccggaa aacttctata tgtatcagtt
     2881 gggcgtaatg ggaactgcgg atctgtgggt cacggatcat ctgctcacca cgggcagcgt
     2941 gtttgccaat atcgccaaca actacgacaa atttaactac accaatccac cgaaggactc
     3001 gcatctgccg cgggtgcgta cgcatgtccg tgagtatgtg cagaatgatg tttatgtgaa
     3061 taacctacag gccaactact tccagtattt tggcaatggt ttctatgggc aggtctatgg
     3121 cggttatctg gagaccatgt ttggcggtgc cggggcggaa gtcctgtatc gcccggtaga
     3181 cagcaattgg gcgtttggtc tggatgccaa ctacgtgaaa cagcgtgact ggcgtagcgc
     3241 gcaggatatg atgaagttta ccgattacag cgtgaagacc ggacatttga ccgcatactg
     3301 gacgccgtcg ttcgcccagg atgtgctggt gaaagccagc gttggtcagt atctggcggg
     3361 cgataaaggc ggtacgctgg agatcgccaa acgcttcgat agcggcgtcg ttgtcggcgg
     3421 ttacgcgacg attaccgatg cgtcgccgga tgaatatggg gaaggggatt ttaccaaagg
     3481 cgtatatgtt tccgtaccgc tggatctctt ctcgtccggc ccaacccgaa gtcgtgcggc
     3541 aattggctgg acgccgctga cgcgtgacgg tggtcaacag cttggccgta agtttggcct
     3601 gtatgatatg accagtgaca ggagcgtaaa tttccgttaa tactcaggcc ggataaggcg
     3661 ttcacggcgc tatccggcaa attaccttat tgaacaaaat ataaacacaa ataaaaaata
     3721 tagatgcccg tcacatttgt gcgttataca gaaacctcgc cgcagagaaa gagggggctg
     3781 ttatgatgcc attatcgcgc tcacgtcttg agtttatcgc cacgatttta caaaacgtac
     3841 taaatttggg gctgcttacc ctcggtctga tcctggtcgt ttttctcggt aaagagacgg
     3901 tgcatctggc ggacgcatta ttcgcgcctg agcaagccag caaatatgaa ctggtggaag
     3961 ggctggtgat ctactttctt tatttcgaat ttattgcgct gattgtgaag tactttaagt
     4021 ctggccttca ctttccgctg cgctatttcg tgtacattgg gatcacggcg attgtgcgtc
     4081 tgatcattgt cgatcataaa acgccaatgg atgtattact ctattcggcg gcgatcctcc
     4141 tgttggttat cacgttgtgg ttatgtaatt cgaaccgact acggcgagaa taggcgtcgc
     4201 cacaccgtaa cggacgtatg gcgtggcaat aaattagccg ctgtctataa cgcataaaaa
     4261 aagcgctccg aagagcgcca aaatacgacc ataagtgggg ataacataac ttgagggcag
     4321 tggcattgcc cgttgccggg caggtacttc gataaaactt aacctttcac accccctgcc
     4381 gtcaggccgt tgaccagcca acgttgcgcc aacaggaaca ccagggtgat aggaatagct
     4441 gaaaggacgg cggcggcggc aaagtcgccc cacaaatagt tttgcgggtt gagatattgc
     4501 tgcataccca cggccagcgt atagctgtcc acatcgcgca gtaacaacga ggcgaccgga
     4561 acttcggtaa tcgccgcgat gaacgacaga ataaacacca ccgccagaat cggtacggaa
     4621 agcggcagca gcaccagacg aaatgcctgc cacggggttg cgccatccag cgcggcggcc
     4681 tcttccagcg agctgtcgat agtttcgaag tagcctttaa ttgtccagac gtgcagcgcg
     4741 atgccgccaa gataggcgaa gatcacgccg ccatgcgtat tcagaccgat aaatggaatg
     4801 tattgtccca ggcggtcaaa taacgcatac agcgccacca gagacaaaac cgccggaaac
     4861 atctggaaaa tcagcatccc tttgagcagt gttgctttac ctggaaaacg cattcgtgcg
     4921 aaagcgtagg cgcaggtggt ggagagcgcc acgatgccga tggcggtaat accggcgatt
     4981 ttcaccgagt tccacagcca cagcaggacc gggaagggag gcggcgttac ccgaccatcc
     5041 gcatgttcca cgctgaaacc cagcgccagc cgccagtgtt cccaggagat tttatccggg
     5101 atcaggcttc cggtggcgaa gttcccttca cgtagcgaga tagcgatgac catcagcagc
     5161 gggaacataa tcgccgcgat gaaaatcagc agccccaggt gcgtgatgaa gagacgcagt
     5221 ttctgagatt tgggttggac catagccatt gttattatct cccttaatca aacttcatac
     5281 gcgtggcttt caggttcact attgccagcg cgcctaccag caggaagatc agcgtggcaa
     5341 tggccgccgc cagaccgaag tcctgaccgc cgccgccttc aaaggcgata cggtaggtgt
     5401 agctgacgag cagatcggta taaccggcag gcgtggtggt gccgagacgg tctggcccgc
     5461 cgttggtcaa taactgaatc aggacaaagt tattaaagtt aaaggcgaag ctggcgatca
     5521 tcagcggcgt tagcggctta atcagcagcg gtaaggtgat tttaaagaaa ttctgaaatg
     5581 gaccagcgcc gtccattgcg gaggcttcgt acaggtcatc cggaatcgct ttcagcagtc
     5641 ccatgcacag gatcatcatg tagggatagc ccagccaggt attcacgata atcaccattg
     5701 cccgcgcggt gttggggtcg ctgaaccagg caggtttaat gccaaacagc gcgctcagca
     5761 tcatattgat ttcgccaaag ctttggttga ataacccttt gaaaatcaaa attgaaataa
     5821 acgacggtac ggcgtagggc agaatcagca ggacgcggta gatagcttta cctttcagcg
     5881 cttcccactg tacgaggcag gccaatacca tcccaaccgc cacggttaac accacagtga
     5941 ggaccgaaaa gaccacggtc cagacgaaga tagcgaaaaa aggcttctgg atcccttcgt
     6001 cggtaaagac gcgcgtaaag tttttcgcgc cgatagtaac ggtataacca ggactgagtt
     6061 tttcatcacc ccagcttccg tcggcgttga tcgactgata ataaccgcta tcgttgtttg
     6121 gccggtattt tacgccgctc tggttattgg taagcaggcc gtcatcagcc agtgtgtaca
     6181 gcggacgggt accggaaaac tgacgcagcg agctcataac cactttactt tcatccggca
     6241 ggacggcggt tatctggttc agcgccagac ggttctgggt gattatccgc agattggcgc
     6301 gttcgccgcc cggcagggca tcggtctctt tcagctgtaa tttttgttcg ccgccgaagg
     6361 aaaatgcgcc agacaggtaa tgtttgcccg tttctccgtc ggtgagggcc agttgccact
     6421 cgtcgccggc cgggtaaaga ccgaagttat aggtttttcc cgcctgataa gaacggtcca
     6481 tcagcacttg ctgggcgcgt tcaaaggtga gctggttggt gctgctgtag ttagtaaagg
     6541 cgatggcgat ggtgcacacc agcgggaata gcacaaacag ccccatgccg gcgaggccag
     6601 ggtaaacgta gcgccaggca taggttttac gatttgcgaa aatatacagg ccagcagagc
     6661 ttaaaatcag cgtcatgatg gcgaacagat actccccttg tacgtacatt aaaactacaa
     6721 ggtaacccac cagcaggccc agcagaccaa ttactgacca tttaagctgg tcgctttgcc
     6781 accagtgttt ctttttaatg acatccatgg gggttttcct ctacagcgtt gaaacttcct
     6841 ggccggagat gtgcctgatg gcgctgcgct tatcaggcct acggtgtgtt gtaggccgga
     6901 taaggcattt atgccgccat ccggcacagg ctcgcggcat tacttggtga tacggctttg
     6961 tgcatctttc agcgcggcat ccacggtttg acggccgctg gcggcgttaa tcacagccgt
     7021 acgtaccgca taccagaagg cggacatctg cggaatattc ggcatgatct cgcctttctg
     7081 ggcgttatcc atggtggcgg cgatacgggg gtctttcgct aactgctcct ggaaagattt
     7141 cagcgccacg gcgcccagcg gtttgtcttt gttcaccgcc tccagaccct gatcggtcag
     7201 caggtagttt tcgaggaact ctttcgccag ctctttattc gggctggcag cgttaatccc
     7261 cgcgctcagc acgccgacga acggtttcga gggtttacct ttgaaggtcg gcagcagggt
     7321 gacaccgtag ttgactttgc tcttgtcgat gttcgaccat gcccacggac cgttgatggt
     7381 cattgccgtt tcgcctttat tgaaggctgc ttcggcgatg gagtaatcgg tatcggcgct
     7441 catatttttg ttcttgatca tatcgatcag gaaagtcaga cctgctttcg cgccggcgtt
     7501 gtcgacgcca acgtctttca cgtcatactt gccgttttca aatttgaacg cgtaaccgcc
     7561 gtcagcggcg atcaaaggcc aggtgaaata cggctcttgc aggttgaaca ttatcgccga
     7621 cttccctttc gcttttagct ctttatccag cgccgggatc tcttcccagg ttttcggcgg
     7681 gttcgggacg aggtctttgt tataaatcag ggagagggct tcaacggcga tggggtaggc
     7741 gatcagcttg ccgttataac gtaccgcatc ccaggtaaac ggatagagtt tgtcctgaaa
     7801 cgctttatcc ggagtaacct ccgccagcag accagactgc gcgtagccgc caaaacggtc
     7861 gtgcgcccag aagataatgt caggaccgtc gccggtggca gccacctgcg ggaatttctc
     7921 ttccagctta tccgggtgct caacggtcac tttaatgccg gtgtcttgct caaatttttt
     7981 accgacctcg gccagaccgt tatagccctt gtcgccgttg atccagataa ccagtttacc
     8041 ttcttcaatt ttggcgagag ccggggcgga aatcatcatc gtcgtaagtg cggataatgc
     8101 gaggatgcct acgccagttt taatcttcat atctcccatc ctttttggtg atgtacacag
     8161 aggtggttta acggtctcta gtttctttat acgacaacct ctttccatcc tccctacccc
     8221 tacgccccac cccggcttta tgtgatctgt gttgcataaa tgtgagtaat gcgtgctggc
     8281 gcacacaaaa acacgccgat ttttgcgggc ggcatcacga aattcctttt ctgtccgcgc
     8341 ccgtggtctc aggcgttgtg tcctcatcct cccgcctcct cccccataaa aaagccgggg
     8401 ggtggaggat ttaccccagt cagggatcgc gcatagtcag gccatcatga atgttgctgt
     8461 caatgacagg ttgtaacgaa gggagaaggg catggcgagc gtacagctac gaaatgtaac
     8521 gaaagcctgg ggtgacgtgg tggtatcgaa agatattaac ctcgatatcc atgacgggga
     8581 gttcgtggtg tttgtcggac cgtcaggctg tggtaaatcg accttgctgc gtatgatcgc
     8641 cgggcttgaa actatcacca gtggcgacct gtttatcggg gaaacccgta tgaatgatat
     8701 tccgcctgcc gagcgcggcg tgggcatggt attccagtct tatgcgctct atccccatct
     8761 ctccgttgca gaaaacatgt ctttcggcct caagctggcg ggcgccaaaa aagaggtaat
     8821 gaatcaacgc gtcaatcagg tggcggaagt actgcaactg gcgcatctgc tggaacgtaa
     8881 gccaaaagcg ctttccggcg gtcagcgtca gcgcgtagcg attggccgca cgctggtggc
     8941 ggagccgcgt gtgtttttgc tggatgaacc gctctctaac ctggatgccg cgctacgcgt
     9001 gcagatgcgc attgaaattt ctcgcctgca taaacgtctg ggccgcacga tgatttacgt
     9061 cacccacgat caggtcgagg cgatgacgct ggccgacaaa atcgtggtgc tggacgctgg
     9121 tcgcgtcgcg caggtcggta agccgctgga gctgtaccac tatccggcgg accgctttgt
     9181 cgcgggcttt atcggctcgc cgaagatgaa cttcctgccg gtgaaagtga ccgccaccgc
     9241 aattgaacaa gtccaggtcg aactgccgaa tcgccagcaa atctggctgc cggtcgaaag
     9301 tcgcggcgtg caggtcggcg ccaatatgtc tttaggcatt cggccggaac acctgctgcc
     9361 gagcgatatc gccgatgtca ccctggaagg tgaagtccag gtggtcgagc agttagggca
     9421 cgaaacacaa attcatatcc agatccccgc catccgtcaa aacctggttt atcgccagaa
     9481 tgacgtggtg ctggtagaag agggcgccac attcgctatc ggcctgccgc cagagcgctg
     9541 tcatctgttc cgcgaggatg gcagcgcatg tcgtcgtctg catcaagagc cgggtgttta
     9601 aggcctccat aaaaaaacga aacgcaaaac cattcgcagt tttagaaggt ggcagcgttt
     9661 aaagaaaagc aatgatctca ggagatagaa tgatgattac tctgcgcaaa ctccctctgg
     9721 cggttgctgt cgcagcgggc gtaatgtccg ctcaggcaat ggctgtcgat ttccacggtt
     9781 acgcccgttc cggtattggc tggacgggaa gcggcggcga acaacaatgt ttccaggtga
     9841 ccggtgcaca aagtaaatac cgtctcggta acgaatgtga aacctatgcg gaactgaaac
     9901 tgggccagga agtgtggaaa gagggcgata agagcttcta tttcgacacc aacgtcgcct
     9961 attcggttaa ccagcagaac gactgggaat cgaccgatcc cgccttccgc gaagcgaacg
    10021 tgcagggtaa aaacctgatt gaatggctgc cgggctctac catctgggcc ggtaagcgct
    10081 tctatcagcg tcatgacgta cacatgatcg acttctacta ctgggatatt tcaggtcctg
    10141 gcgcaggtat cgaaaatatc gatctgggct tcggtaagct ttcgctggcg gcgacccggt
    10201 ctactgaagc gggcggctct tacaccttca gcagccagaa tatttatgat gaagtaaaag
    10261 ataccgctaa cgacgtcttt gacgtacgtc tggctggtct gcaaacgaac ccggacggcg
    10321 tactggagtt gggcgttgac tacggtcgcg ccaatacgac cgatggttat aagctggctg
    10381 atggggcatc gaaagacggc tggatgttca ccgccgaaca cacgcaaagc atgttgaaag
    10441 gctataacaa gtttgtcgtg caatatgcca ccgatgccat gaccacgcag ggtaaaggcc
    10501 aggcgcgcgg ttccgacggt tcttcatctt tcactgaaga attgcctgat ggaaccaaaa
    10561 ttaattatgc caataaggtc atcaataata atggcgatat gtggcgtatt ttggatcatg
    10621 gcgccatctc gcttggtgat aaatgggatt tgatgtacgt cggtatgtac cagaatatcg
    10681 attgggataa taacctgggt actgagtggt ggaccgtggg cgtacgtcca atgtacaagt
    10741 ggacgccaat catgagtacc ctgctggaag tcggctacga caacgtgaaa tctcagcaga
    10801 ccggcgatcg taacaatcaa tataaaatca ccctggcgca acagtggcag gcgggcgaca
    10861 gcatctggtc gcgtccggct atccgtattt tcgccaccta cgcgaaatgg gatgagaaat
    10921 ggggctatat caaagacggc gataacattt cccgttatgc cgcagcgact aactccggca
    10981 tttccaccaa cagccgtggc gatagcgatg agtggacctt cggcgcccag atggaaatct
    11041 ggtggtaata cgatggtcat ctgacgtaac gaggggcgca agcccctctg aaacatcagg
    11101 tctgatgatg cttgtaagcc gaataaggcg ccagccgcca ttcggcgata tgtttgggtt
    11161 ggcgcgctat tgcctggcta ccgctgaacc cgccttattg aggtgagaat aatgaaaatg
    11221 aagaaaagtc tcgtcgccct ctgtttaacc gcagggctgt tcgccagcgt gccgggtatc
    11281 agcctggcgg aagtgaacta tgtaccgcaa aataccagtg ccgcgcccgc tattcctgct
    11341 gctgcgctac agcaattaac ctggacgcct gtagatcagt caaaaacgca gtctacccaa
    11401 ctggcgacgg gcggccagcg ccttgacgtc gccggcatta ccggcccggt cgccgcttat
    11461 agcgttccgg cgaatatcgg cgagctgaca ttaactctga ccagcgaggt caataagcaa
    11521 gccagcgttt ttgcgccaaa cgtgttgatt cttgaccaaa atatgacgcc ttcggcgttc
    11581 ttccccagca gttactttac ttatcagcag ccgggcgtca tgagcgcaga tcggctggaa
    11641 ggcgtgatgc gcctgacgcc tgcgttgggg cagcagaaac tctatgttct ggtgtttacg
    11701 accgaaaaag atcttcagca aactactacg ctgctcgatc cggcaaaagc ctatgccaaa
    11761 ggcgtcggta actctatccc ggatattccc gatccagttg ctcgccatac cactgatggc
    11821 gtggtgaaac tgaaggtgaa aaccaacagt agctccagcg tattggtcgg gccgttgttt
    11881 ggctcgtccg gtaccgggcc ggtaacggta ggcaataccg ccgcgccggt cgctgcgcca
    11941 gcgccagtcg cgccgaagaa aagcgaaccg atgttgaacg atacggaaag ctactttaat
    12001 aaagcgatta aggatgccgt agcgaaaggc gacgtcgata aagcgctgaa actgcttgat
    12061 gaggccgaac gtctgggatc gacatctgcc cgttccacct ttatcagcag tgtaaaaggc
    12121 aaggggtaat tgtttcccca cagtgctgat tttgcagcaa ctggtgcgtc tcctggcgca
    12181 cctttttttg tcatttcatg cgaattgtta tttttttgtt gcgcaacaga tcacttaatt
    12241 gtgattgcgc cccccgtaat gtcttttctg agatacaatg actttaggtt atgaatcgga
    12301 gagtaaggca tgtcacaccc tgcgttaacg caactgcgtg cgctgcgcta ttttgatgcg
    12361 attcctgcgc ttgaacccca tttgctggac tggctgttgc tggaagattc tgtgactaaa
    12421 cgttttgagc agcagggaaa gcgggtaagc gtgacgctga ttcgggaagc gtttgtcggc
    12481 caaagtgagg tcgaggaagc atcaggttta ctgccatccg agtcccgcta ctggttacgt
    12541 gagatactgc tttgcgctga cggcgagccc tggcttgccg gacgtaccgt ggtaccggaa
    12601 tccacgctgt gcggacctga acaggtctta caacatctgg gtaaaacccc gcttggacgt
    12661 tatctattta catcatcgac actgacccgc gattttattg aaattggacg cgatgcaacg
    12721 ctgtgggggc gccgctctcg actgcggttg agcggaaaac cgctgttgct taccgagctt
    12781 tttttacctg catcgccgct gtactgagag gaagataaag atggagtgga gtctgacgca
    12841 gagtaagctg ctggcgtttc accgtttgat gcgtacagat aagcctattg gcgcgttgct
    12901 gctgctctgg ccgacgcttt gggcgctatg ggtggcgacg ccgggtatgc ctcagctgtg
    12961 gattttggca gtttttgtcg ctggcgtgtg gttaatgcgc gcggcgggct gcgtggtgaa
    13021 tgattatgcc gatcgtaaat ttgacggaca tgtaaaacgt acggtcaacc gacctttacc
    13081 cagcggcgcc gtgacagaga aagaagcgcg caacctgttt gtggtgctgg tgctgctggc
    13141 gtttctgttg gtgctgacgc tgaacgccat gacgattctg ctttccgtgg cggcgctggc
    13201 gttggcctgg gtttatccct ttatgaaacg ctacacccac ctgccgcagg tcgtgctggg
    13261 ggccgctttc ggctggtcaa tccccatggc gttcgccgcg gtgagcgaat ccctgccgtt
    13321 gagctgctgg ctgatgttcc tcgccaatat tctctgggcg gtggcttacg atacgcaata
    13381 tgcgatggtc gacagagatg atgatatcaa gataggcatt aaatcgactg cgatcttgtt
    13441 tggtcgttat gacacattga ttatcgggat tctgcagctt ggcgtcatgg cgttaatggc
    13501 gctgatcggc tggttgaatg gtctgggatg gggatattac tgggctgtgc tggtggcggg
    13561 cgcgctgttt gtctaccagc aaaaactgat tgcgaaccgt gaacgtgaag cctgctttaa
    13621 agcctttatg aacaataact acgttggcct ggtgctattt ttagggctgg cgatgagtta
    13681 ctggcacttc tgatgtcatg ccgggcgaac ccggcctaca aagccaaaat tttcaatacg
    13741 tcatatcagt tgcccgatga gcttgcacta tcgggcattt caggcactgg cttactcgcc
    13801 ctgcgtcgcg ctttcaatcg tcagacggac atcagaggta attagatcgg caagcatctg
    13861 atatatcttc atcgtttctg ccggttcggc atcgcccgta tcactgatat aaccctcatc
    13921 ccgtagcgtc aacacgagtg aactgaacac cgctttgtcg aaaaactccg gcgcgttaat
    13981 accgtgcagg acagacagac gttgcgccac ggtacggctt tctttctcca gcgtactgcg
    14041 gttgatggac ggattggcgc tcaatagcca gaacgtaatg gcataacgct gtagcgtttc
    14101 acgcgcgcct gccgccagca gttgcagcgt acgggaatgc gtcgggttga tatgcagttc
    14161 atcatcctgc agggtaatta gcccctgacg ctgcatttca ctggccagcg cgtcgatgac
    14221 cgaggctaac tcctcgcgct cccagcgcag gaacagctcc gcttttaaca tcggatagag
    14281 cgcttcaaca tgctgctgca acgcatcacg cgaaatgcga cgatgctggg tgataatcgc
    14341 cgccatcagc gaaggcataa tcaacatatg cgcgatattg ttacgataat aggtcatcaa
    14401 caccgcctgc tcgcgcggca ggatgatgat atcgccaatg gtgtctttct cgacctcaaa
    14461 cttattcatc tgcagcgcgt gagcgatgag ctcgccagcg ctggcggcag gaaccgttga
    14521 gtctgtggaa taagggacat tgcgcatcag atcgagatag cagtcaagct gctcggtgag
    14581 ctgctcgcgg gtgagcgagc gctgacgcga cgctaacagc gcggtacaac acaggttcat
    14641 cgcgtttgcc gcgccagcgt tgttaatacg caccatcaga tcggcggcaa tactatttac
    14701 cgtcggcgtc agccaggctg ggcgtatggc ctctataggg tcgatagatt cgcgccactc
    14761 tggcacatgc tggttcaggt acgtcatgag cggcatcggt tcgccaaagt taacgtagcc
    14821 ctgacccaga ttgcgcagct tgctcaagcc tttcagcatc tgcggcagac tctctttctc
    14881 ttttgtcgcg ccgcgcagct ctttcgcata ggtgcccact tccatgacgt gctcatagcc
    14941 aatgtagatc ggtacgaggg taattgggcg ggtaccgccg cgtagcatcg cctggatagt
    15001 catcgacagg gtgccggttt tcggatctaa caaacgtccg gtacgcgaac gtcctccttc
    15061 ggcaaaatac tcaaccgagt aaccgcggct gaacagctcg cccaggtatt cgcgaaagac
    15121 ggtggaatag agtttattcc ccttaaaggt gcgacgaata aagaacgcgc ccagacgacg
    15181 gaaaattggg ccagcgggcc agaaattaag gttaataccg gcggcaatgt gcggcggaac
    15241 cagcccctga tggtacagca cataagaaag gagcaagtag tccatatggc tgcggtgaca
    15301 gggtacatag acgatttcat gcccgtcgtg cgccagttgg cgtacgcgct cggcgttatg
    15361 cacgttaatc ccctggtaaa gtcggttcca ggtaaacccc aaaatcctgt cggtcaaacg
    15421 aatcatctcg taagagaagt tcgccgcgat ctcttccatc agcgcaatgg cgttttgctg
    15481 cgctttttca tgagagattt tcttactgcg cgcttcgtct tctaccgcgc gggcgatcgc
    15541 tttcgaggcc agcagtttgt taaacagatc ctgacgggcg ggcaggcgtg ggccaaccgc
    15601 cgccaggcgc tggcgagcaa agtgcatacg cgccacgcga gccagcttct gcgcgatgat
    15661 tttatcggtg ccgtgttcat cagccatgcg acgcaatgag acggacggcg agaatcggac
    15721 aaagctatcg cggcccagcc aggagatggc aaagaatttc tgtacgccgt tcagcatacg
    15781 taaaggcggg ttctcttctc ctttttcacg acccggcgcg cggccaaaca tcacggaaac
    15841 gggcaccatc tgcacgtcca aagctggatt actccgatgc agatcgagat aatcgtgaaa
    15901 aagtttcacc gactcttctt ttggcgtgta ataggtaaag acacgcggtc cgccgtgaat
    15961 aaatacatag cgtggcaaca gcgcgccgtc gatctccagc ggctccagcg gatccgggag
    16021 atcgtgcgcc agacattgcg cccgcagcgt cagtaagtcc gcttttgagt tgtatggcaa
    16081 gacatacata atggggcgag aagtatcgag ccccaattcc tgggcgggtt ccgccggaat
    16141 agacttgctt tttaccagta tgcttaatgg taaattcagt aatttgtagt aaattcgtgg
    16201 ccagccggac ataaacgatg taaagcctct ggttaataat gcaaatgcgg tgcaaggata
    16261 tcagaaagtt tagcgaattt ctgttgtatc ccgtcatact tcgcgctgcg ttacggcagt
    16321 ccgaatcgtg cagggcaacc gtataatgtc attgacgtta ataatgtaaa aaggttcttt
    16381 tgatggccaa taataccact ggattcacca gaattatcaa agcggcagga tattcctgga
    16441 aaggatttcg cgccgcatgg actcacgaag cggcgtttcg ccaggaaagc ctcgcggtat
    16501 tgctgggcgt catcatcgcc tgctggctgg atgtggatgc gattacccgt gtgttattga
    16561 taggttccgt tttacttatc atgattgttg aaatcctcaa cagcgctatt gaagcggtcg
    16621 ttgaccgcat cggttctgaa taccatgagc tttccggccg tgcgaaagat atgggatcgg
    16681 ctgcggtgct actgtctatt ttcgttgccc tgatgacctg gggcatcctg ttatggtcac
    16741 attttcgata aaggttccaa attttataaa tctcttgttt tttgcgccgt ttgtggttcc
    16801 aaaatcacct ttaactgtat atactcacag catgactgta tatacaccca gggggcggaa
    16861 tgaaagcgtt aacggccagg caacaagagg tgtttgatct catccgggat cacatcagcc
    16921 agacaggtat gccaccgacg cgtgcggaaa tcgcgcagcg tttggggttc cgttccccaa
    16981 acgctgcgga agaacacctt aaggcgctgg cgcgcaaagg ggtgcttgaa atcgtttccg
    17041 gcgcatcgcg aggtatccgt ctgttacagg aagaagagga cggattaccg cttgtcgggc
    17101 gtgtcgcggc gggtgaaccg cttctggcgc agcagcatat tgaaggccat taccaggtcg
    17161 atccttcact gttcaaaccc agcgccgatt tcctgctgcg cgtgagcggt atgtcgatga
    17221 aagacatcgg tattatggat ggggatttgc tggcggtaca taaaacgcag gacgtccgta
    17281 atggccaggt ggttgtcgct cgcattgatg atgaagtgac agtaaaacgg ctgaaaaagc
    17341 agggcaataa agtggaactg ctgccggaaa acagcgagtt tacaccgata gtggtggatc
    17401 tgcgcgaaca aagctttacg attgaagggc tggcggtagg cgtcattcgc aacggggaat
    17461 ggttgtaatc tctttttaat ctccttgtaa gccgccatcc ggcaatcgtg tagcctgatg
    17521 gcgctgcgct tatcaggcct acgggaatgc agttcctgag atgattaatt tgtaggccgg
    17581 ataaggcgtt acgtcgccat ccggcaatgc gctcgtttcg tttaactcct tgtcaggctt
    17641 ttctccatgc cgctttttac ctcctctgat aaagctctct ggcgtcttgc gttgccgatg
    17701 attttttcta acatcaccgt ccccttactg gggctggtcg atacggcggt gattggtcat
    17761 ctggacagcc ctgttttcct gggcggcgtg gcggtgggcg cgactgccac cagctttctt
    17821 ttcatgctgc tgctatttct acgtatgagc accaccggcc taacggcgca ggcatttggc
    17881 gccaaaaatc cgcaggcgtt agcccgggcg ctcattcaac cgttattgct ggcgctgggc
    17941 gcaggcgtga tgattgtgct atttcgcacg ccgcttatcg agctggcttt acatattgtc
    18001 ggcgggaacg acgctgtcct ggtgcaggcg agacgcttcc ttgaaattcg ttggctaagc
    18061 gctcccgcgt cactggcgaa tctggtgctg ctcggttggc tgttaggcgt tcagtatgcg
    18121 cgggcgccgg ttatcttgtt ggtcgtgggc aatatcctca aaatcgcgct cgacctgtgg
    18181 ctggtgatgg ggcttcatat gaacgtgcag ggtgccgccc tggcgacggt catcgcagaa
    18241 tatgtcacgt tactgatcgg cctcatgatg gtacgtaaag ttctccatct ccgcggtgtg
    18301 tcgctggata tgctaaaaca ggcctggcgc ggcaacgtgc gccgcctttt ggcgctcaat
    18361 cgcgatatca tgctgcgctc attgctcctt cagctttgtt ttggcgcaat cacggtgtca
    18421 ggcgcgcggc tgggcagcga tattatcgcg gtaaatgcag tcctgatgac cttactcacc
    18481 tttacggcct atgcgctgga cggttttgct tatgcggtgg aggcgcactc cggtcaggct
    18541 tacggcgcgc gtgacggtag caagctactg gacgtctggc gagcggcgtg tcgtcagtca
    18601 ggaattgtgg ccttgttgtt ttccacggtc tatgccctgg caggcgaaca tattgtcgcg
    18661 ttactaacct cattgccgca aatacagcta ctggcggatc ggtatcttat ctggcaggtg
    18721 gtattaccgc tggtgggcgt atggtgctat ctgctcgacg gtatgtttat tggcgcgacg
    18781 cgcgctgccg aaatgcgcaa tagcatggct gtcgccgcgg gaggattcgc gctgacgctc
    18841 ttcgccctgc cggtattagg aaatcatggt ttatggctgg cattaaccgt atttctggcg
    18901 ctacgcggtc tgtcgttgag ccttatctgg cgtcgtcact ggcgcgaggg tacatggttt
    18961 gccagatcgt gatggttaaa aattctgaat ataaaaccga aggccgaatt cctgcctaca
    19021 attattatca cgtccagcag aaattgcagt gcatttgggc gaataacacc tgctattcct
    19081 aaccgaatga tgaggacaag atgatgaata aagacgaagc cggcggtaac tggaaacagt
    19141 ttaaaggtaa aatgaaagaa caatggggca aactgaccga tgacgatatg accgttatcg
    19201 aaggtaaacg cgaccaactg gtaggtaaaa tccaggagcg ttacggttac cagaaagatc
    19261 aggcggaaaa agaggttgtt gactgggaaa cccgtaacaa ctatcgctgg taatatgttt
    19321 tcccctatca ggagtacatg gatgtgcttc ccactgtttg cttatgaatg cgggcgtgcc
    19381 cctctctact gccgcccgtt tttccgttca ggctaacgcg gttttttctt caccagcacc
    19441 gagtgatcgt gaccacagtc gcccggatgg cgacacgctt ccacttctac gcacgcaggg
    19501 cacagaccgt gcgcctcaat aacgttatgt cgtagcgcaa agcccatttt agccgccagc
    19561 gtatgcatga tgtcttccac gccctcggca cactcttcct tcaccacgcc gcaacgatcg
    19621 cagataaaca tggccgagct gtgcgtcggc tggtcgaaca ggtggcaaac cacataacta
    19681 ttggtggatt ccactttatg gacaaaaccc tgttcgagca aaaaatccag cgcgcggtag
    19741 atggtgggcg gtttggcctg tggttccgtt tcgcgcagca aatcgagcaa atcgtatgcg
    19801 ctgatggcac cctgttgcag actcatcagg cgcagcactt cgaggcgctg aggcgtcagg
    19861 cgcacgttgc gctgcgcgca gagtttttca gcttgcgcca gtaactcttg cgttgtggtc
    19921 ttttccatgt agcacctcga atggcatgaa agtctaatcc gttactttac cacgagctgc
    19981 ttaaaactct gaaattaccc cgcgacaata tatcgcctgc taagcttttc cgcgccagta
    20041 ttctcatcta tacataatga gggtcgatat tataacaaca ggatttaaca tcactatttc
    20101 acagcaatag ttcgcctctg tccggtaaag cgtggcggag ggattacttc acctgataat
    20161 aagatgggct aactgtgaac aaaaacgtca aactttcact gattgctatc gcggtctcgc
    20221 tttttatgac aaagcaggcg ggcgccgcca atacctggac ggaagcgcgt aatgacgcaa
    20281 tgggcgggac gggcgttgcg tccgcgaatt atggcagcgg agtactatta aatccggcgt
    20341 tactggcaaa agccaaaccg gaagacaata tcactgttgt ccttcctgcg gtcggcgtcc
    20401 agattacgga taaagacaat ctccaggatg aaattgacga tatcagcgat aaagtggatt
    20461 actacgatga ggtcgtcgat aaccttacgc tggggcaaat tctgctcaat ccgcgaggcg
    20521 tgctgaatca atttcagggc gccgcgcgcg acctggccga tgagctggaa tatctcaacg
    20581 gaaaaaccgc ccgcgccaat gccggcgccg ggttggcggt aagtattcca gggcaaacgc
    20641 tttccgtggc gtttatcgcc aaaggttatg cgcatgggcg cgtgagttcg tccattgatc
    20701 agaacgatat tcagtatctg cgcgatatcc agcatgatga acgtgtcgcg cttcgtgaag
    20761 caggacgcgc tgctttgctg gggtctgacg aaattacaaa gcatttaaac tctaccgcgt
    20821 tggggcgggt agcgattgta tctgactacg gtattgcgct ggcgaagcag tttgtggtgg
    20881 gcgaggtgcc tgtttccatt ggcgttacgc caaaactgca aaaaacctgg ctctataact
    20941 acaccacctc aatttataac tacgacagta gcgactggaa tagcagccgt tatcgcaatg
    21001 acgatacggg ttttaacatt gatgcggggc ttgctgccga tatcggtgaa aactggacgt
    21061 tggggctgag cgggcaaaat ctggtatctc gcgatatcga tacgaaagat atttacatca
    21121 ctaatggtat gacgggagaa accaccaact acaaagagac ataccaaatc cgccccctgg
    21181 ttaccgcggg catcgcatgg cataacgatt tgctgaccgt aagcgccgat ggcgatctga
    21241 cggaaacgaa aggctttaag agcgaagaca attcacagta cgttggcgtc ggcgctgaag
    21301 ttcgaccgtt gtcatggctg gcggtgcgcg cagggtatcg tgcggatgtg aaaaataacg
    21361 atagcaatgt ggttaccggc ggtcttggct ttgcgccctt taaccgtgcg catctcgatt
    21421 taatgggact gtacggcgaa gatgaaacct ggggggcagg cgcgcagctt acaatgacat
    21481 tctgaggtgc tttcaccgga ggcgctacgc ctccggttta gcgttatgct atagtaacgc
    21541 ccctttttta accggatgct tatttattcg ccatgcagcc tgaaacccag tcctccgctt
    21601 tacctgctta tcgcttctcc atcgcgccta tgctcgactg gacggacaga cattgccgct
    21661 atttcctgcg tttgctgtct cgccagacgc tgctctacac cgaaatggtg accacgggcg
    21721 cgattattca cggtaagggt gactatctgg cttatagcga agaagagcat ccggtcgctc
    21781 tacagcttgg tggaagcgat ccggctcagc ttgcgcattg tgcaaagctg gcggaagcgc
    21841 gtggctacga tgaaattaac ctcaacgtgg ggtgcccttc cgatcgcgtg caaaatggta
    21901 tgtttggcgc ctgtttgatg ggcaatgcgc aactggtcgc cgattgtgtt aaagccatgc
    21961 gtgatgtcgt ctcgattccg gtgacggtaa aaacccgcat tggtattgac gatcaggaca
    22021 gttatgcgtt cctgtgtgat ttcattaata cggtttccgg tcagggcgaa tgcgagatgt
    22081 ttattatcca tgcgcgcaaa gcctggcttt ctggcttaag cccgaaagaa aatcgtgaga
    22141 tcccgccgct ggattacccg cgcgtctatc agctaaagcg ggattttccg cacctgacca
    22201 tgtccattaa cggcggcatc aaatcgttgg aagaggcgaa ggaacacttg cgccatatgg
    22261 atggcgtcat ggttggccgc gaagcttatc agaatccggg tatactggcc gcggtggatc
    22321 gggagatctt tggcgccgat accaccgata ccgacccggt tgcggtggtt cgcgcgatgt
    22381 atccctatat tgagcgtgaa ttgagccagg gagcgtatct ggggcatatc actcgccata
    22441 tgctggggtt gttccagggt atccccggcg cgcgacagtg gcgtcgctat ctgagcgaaa
    22501 acgcccataa agctggcgcg gatgctgctg tactggagca ggcgctaaaa ctgatagcag
    22561 acaagcgtta aaagttcgcc aaaaattagt caatctcacc acgctctgcg cagttttgca
    22621 gggcgttttc tttatatatc aaaaacataa atattggcat gatttttgta atagcttacc
    22681 tgaccaaacc cggtaagcgc cgtgccgccg ggcaatgcca tctttatggg gagcgactat
    22741 gctggaacta ctttttgtgc ttggcttttt tctgatgtta atggtgacgg gcgtctcctt
    22801 gctgggcatt ctggccgcgc tggttgtagc gactgccgtc atgttcttgg gcggaatgtt
    22861 cgccctgatg atcaagctgt taccgtggct actgctggcg gtggctgtgg tgtgggtgat
    22921 caaagcagta aaaacgccaa aaatcccaca gtatcagcgc aataaccgtc ggttttacta
    22981 aggtattgag cggttcgtca caacctggaa ctttgccgtc acaagcaaat aggaatcgat
    23041 tattaaatct gtcatgattg cgcaggtaac gaattcatcg cgctgtaccc tacatacagc
    23101 cgaacaaaaa aagaaagggc ttcccgggtg gaagcccaat ttctttgcag agctattacg
    23161 gaatcagcag gcttgagccc tgtgtggccc ggctttccag cacctcatgc gcgcgacggg
    23221 catcttttaa cgcatagcgt tgattttcag ccacatcaac tttaatcacg ccgctggcga
    23281 tcaatgagaa caattcattg ctggcttcgg tcagttcttc acgcgtcgta atatacccct
    23341 gtagtgaagg tcgcgtggca tacagggaac ctttctgatt cagaatacct aaattcacgc
    23401 cggtgacggg gccggacgca ttgccgaaac tgaccatcag tccccgacgt tgcaggcagt
    23461 ccagtgaggc ttcccaggta tctttcccca cggagtcata gaccacgcgg acttttttgc
    23521 cgccggtgat ctcttttacc cgttcgacaa tgctctcctc acggtaatta atcacctgcc
    23581 aggcgccggc gtccagcgcc cgctgcgctt tttgcgcgct accgacggta ccgataagct
    23641 tcgcgcccag cgctttcgcc cattggcagg cgatcagacc gacgccgccc gcagcggcat
    23701 gaaacaggaa gggttcgtcg ggtttcactt cataggtttt gcgcaacagg taaaaaacgg
    23761 tcaatccctt gagaaaagag gctgccgcct gttcgaaaga aatggcgtca ggcaaaatcg
    23821 cggctttatc tgcggggacg ttatggacgg aactgtaagc gccgagcgtt gactgcgcgt
    23881 agacgacgcg atcgcccacg cgaatgtgct ccacgccgct gccgacttta ctgaccacac
    23941 ccgcagcttc ggttcccagg cccgcaggca acgacggggg cggatagagt ccgctacgga
    24001 tataggtgtc gatgaagttg ataccaatgg ctttgttctc aacctggatt tcgtgttccg
    24061 ccggttccgt tggcgtaaac tccacggtct gaagcacttc cggaccacca tgcttgtgaa
    24121 attcaatacg cgttgccatg cttcctccaa aagaaatgtg gtaatctttc gacccaatca
    24181 ctatctcggt aactccattc actatggcag gaaataaacc cttcaacaaa ccacagactg
    24241 atgcccgcga ccgcgatccg caggttgccg ggataaaagt gccgccgcac tcgattgaag
    24301 cggaacagtc ggtgttgggc ggtttaatgc tggataacga gcgctgggac gatgtggccg
    24361 agcgcgtggt ggcggaagat ttctataccc gcccgcatcg ccatatcttt acggagatgg
    24421 ggcgcttgca ggaaagcggc agtcctatcg acctgattac gctcgcggaa tcgctggagc
    24481 ggcagggcca actggacagc gtcggcggtt tcgcctatct ggcggagctg tctaaaaaca
    24541 cgccaagcgc ggcgaatatc agtgcttatg cggacattgt gcgcgaacgc gccgtggtcc
    24601 gcgatatgat cgcggtggcg catgaaattg cggacgccgg ttacgatcca caggggcgca
    24661 atagcgacga actgctggat ctggcggagt cgcgcgtctt ccagatcgcg gaaaaccggg
    24721 ccaacaaaga cgaaggtccg aaaagcatcg accagattct cgacgccacc gtggcgcgta
    24781 ttgagcagtt gttccagcaa ccgcacgatg gcgttacagg cgtggatacc ggctatcagg
    24841 atctcaataa aaagacggca ggattacagc gttcggattt gattatcgtc gcggcgcgtc
    24901 cctccatggg taaaaccact tttgcgatga acctctgcga aaatgcggcg atgttgcagg
    24961 ataaaccagt actgatcttc agcctggaga tgcccggcga acagatcatg atgcgtatgc
    25021 tggcctcgct gtcccgcgtc gatcagacac gtattcgtac cggtcaactc gatgatgaag
    25081 actgggcgcg aatctccggc acgatgggca ttctgctgga gaaacgcaat atgtatattg
    25141 acgactcctc aggtcttacg ccgacagaag tccgttcgcg cgcgcggcgt attttccgcg
    25201 aacatggcgg gttaagtctg attatgatcg actacctgca attgatgcgt gtgccgtcgc
    25261 tttctgataa ccgtactctg gaaatcgccg aaatttctcg ctcgttgaaa gcgctggcga
    25321 aggaactcca ggtgccggtc gtggcgctat cgcagcttaa ccgctccctg gaacaacgcg
    25381 cggataaacg tccggtgaac tccgacctgc gtgaatccgg ctctattgaa caggatgccg
    25441 acttaattat gtttatctac cgtgatgagg tttatcacga gaacagcgac ttaaaaggca
    25501 ttgctgaaat tattattggt aagcagcgta acggtcctat cggtacggtt cgtctgacgt
    25561 tcaatggtca gtggtcgcgc ttcgataact atgcgggacc gcaatacgat gatgagtaac
    25621 tctccgtcat tcttttaaca aggaattcaa atgcaagcgg caacagtcgt cattaaccgc
    25681 cgcgctctgc gacacaacct gcaacgtctg cgtgaactgg cgcctgccag taagctggtt
    25741 gcggtggtga aagcgaacgc ttatggacac ggtcttctgg agaccgcgcg aacgctccct
    25801 gatgctgatg cttttggcgt ggcgcgtctt gaagaggctc tacgtctgcg agcgggcggg
    25861 attacgcagc ctatcctgct gctggagggt tttttcgacg ccgccgattt gcctaccatt
    25921 tccgcgcaat gtctgcatac cgccgtacat aatcaggagc agcttgccgc cctggaggcg
    25981 gtggagctgg cggagccggt aacggtctgg atgaagctgg ataccggtat gcatcgtctc
    26041 ggcgtgcgtc ccgaagaggc ggaggcgttc taccagcgtc tgacgcactg taaaaatgta
    26101 cgccagccgg tgaatatcgt cagccatttt gcccgtgcgg atgagccgga atgcggcgct
    26161 accgaacatc agctcgacat ttttaatgcc ttctgtcagg gtaaacccgg tcagcgctct
    26221 attgccgcgt ctggcggtat cctgctgtgg ccgcagtctc actttgactg ggcgcgtccg
    26281 ggcatcattt tgtatggcgt atcgccgctg gagcacaaac cttgggggcc ggattttggt
    26341 tttcagccgg tgatgtcctt aacttccagt ttgatcgcgg tgcgtgacca caaagcgggc
    26401 gaaccggtgg gctacggcgg gacatgggtg agtgagcgcg acacgcgcct gggcgtggtg
    26461 gcgatgggtt atggcgatgg ctacccacga gcggcgcctt ccggtacgcc agtactggtc
    26521 aatggtcgtg aagtcccgat tgtcgggcgg gtggcgatgg atatgatttg cgtggatttg
    26581 gggccaaacg cgcaggataa cgcgggcgat ccggtggtct tatggggtga aggtctgccg
    26641 gttgaacgta tcgctgaaat gacaaaagta agtgcttacg aacttattac gcgcctgacc
    26701 tcaagggtgg caatgaagta tattgattaa atgcgcggcg ggccgggtgg cgcttgcgct
    26761 tatccggctt gtatcgcgca tgggctgcag gccggataag acgttcacgc cgtcatccgg
    26821 taatatgcgc atccaccaca acatcctctc gatcttctcg tccttccggt ttattgtgtt
    26881 atttcctgcc ctctgtaaac ctggagaacc atcgcgtgtt tcaaaaagtt gacgcctatg
    26941 ccggcgatcc gattctttca ctgatggagc gttttaaaga cgactcccgt cacgacaaag
    27001 taaatctgag cattggcctg tattacaacg aagacgggat tatcccacag ctcaaaacgg
    27061 tggccgaagc cgaagcccgg cttaacgcgc agccgcatgg cgcctcgctg tacctgccga
    27121 tggaaggact caatacttat cgccatacta tcgcgccttt gctctttggc gccgatcacc
    27181 cggttcttca gcaacagcgc gtggccacta tccagacatt aggtggttca ggcgcgctga
    27241 aagtgggcgc ggattttctg aagcgttatt tccccgacgc aggcgtatgg gtgagcgacc
    27301 ctacctggga aaaccatatt gcgatatttg ccggggcagg attcgaagtg agtacttacc
    27361 cctggtatga cgacgcgact aacggcatcc gttttaacga tctgctggcc acgctgaata
    27421 cgttacctgc gcgcagtatc gtgctgctgc acccctgttg tcacaacccg accggggcgg
    27481 atttaacgcc ttcgcaatgg gatgcggtga ttgagatagt gaaagcgcgc gatctgattc
    27541 cgttccttga tattgcctat caggggtttg gcgcaggcat ggacgaggat gcttacgcta
    27601 ttcgcgccat tgccagcgcc gggttacctg cgttagtcag taattctttt tcgaagattt
    27661 tctcgctgta tggcgagtgc gtcggcggcc tgtcggtggt gtgtgaagat gccgaaatcg
    27721 ccgcgcgggt tctgggacag ctaaaagcga cggtgcgccg aatttactcc agtccgccgt
    27781 gtttcggcgc tcaggtggtc gctacggtcc tgggcgatga ggcgttaaaa gcgagctggc
    27841 tggcggaagt cgacgcgatg cgtacccgca ttatatcgat gcgccagacg ctggtgaaag
    27901 agctgaaggc ggagatgcct gaccgcaact tcgattactt gttacagcag cgtggtatgt
    27961 tcagctatac cgggttaagc gcggagcagg tcgatcggtt gcgcgatgag tttggcgttt
    28021 acctgattgc cagtggccgc atgtgtgtcg ctgggcttaa tgcttcaaat gtacaccgcg
    28081 tggcgaaggc atttgccgct gtcatgtaat attcaggccg gacggcgata acagtgctct
    28141 ccggtctgac aatagctgtt gtgatcatcc tcttttttcg taacaaaacc gcaaataatc
    28201 cttccttttg accgttactg gcgttatggt cagatagttt tttgaccaaa gactcatctt
    28261 aataattata atattttgaa ttttaaggga aaagcatgaa aaaaataacc ctggcgctga
    28321 gcgccgtctg tttattgttt acgctaaacc attccgcgaa tgcgttagta tcttcccctt
    28381 cgacgctcaa tccgggcact aatgttgcaa aactcgcgga acaagcacct gtccattggg
    28441 tctctgtcgc ccagattgaa aacagcctga ccggacgccc gccgatggcg gtcggctttg
    28501 atattgacga caccgtgtta ttttccagcc ccggattctg gcgcggaaag aaaacctatt
    28561 ccccggacag cgacgattat ctgaaaaatc cggccttttg ggaaaaaatg aacaacggct
    28621 gggatgagtt cagtattcca aaagaagtgg cccgacagct cattgatatg catgttcgcc
    28681 gtggcgacag tatttacttt gtcactggtc gtagtcagac gaaaacggaa actgtgtcga
    28741 aaacgctggc ggataacttc catattccgg cggcgaatat gaatccggtg attttcgccg
    28801 gcgataaacc gggacaaaat acgaaagtcc agtggctgca ggagaagaac atgcgtatct
    28861 tctacggcga ttcggataac gatattaccg cagctcgtga ttgtggtatc cgcggtattc
    28921 gtatcctgcg cgcggctaac tccacctaca aaccgctgcc gcaggcagga gcgtttggcg
    28981 aggaagtcat tgtcaactcg gagtactaaa aatcaggaga gcgacaggct ctcctttttt
    29041 gcatgatttt tgcacaaact tgccccgctg gcttttacct tttccagact tgctgcacac
    29101 tattcaggag acgtttgttt ttaggaagga gcagcctatg tggtatcagc gcaccattac
    29161 actgagcgag aagccgcgcg ggtttcatct aataacagat gaaattaccg ataaattgtc
    29221 tggcttaccg cctgtcgaaa cgggtttgct gcatctgttg ttgctacata cctcggcctc
    29281 gctgacgtta aacgaaaact gcgatcccac cgtgcgcgct gatatggagc gccatttcct
    29341 gaaaaccgtt cccgataatg cggcgtatga acatgattac gaaggggcgg atgacatgcc
    29401 ttcgcatatt aagtcgtcag tattgggcgt ctcgttgctg ctgcctgtac gccaggggcg
    29461 tttacagtta ggaacatggc aaggtatctg gttgggagag caccgtattc acggcggtcc
    29521 acgtaaaatc atcgcgacac tacaagggga atgataatga ccatttcgga attactgcaa
    29581 tactgcatgg caaaacctgg cgcagagcag agcgttcaca gcgactggaa agcgacgcaa
    29641 attaaagtgg aagatgtact tttcgcgatg gtaaaagaag ttgatgggcg cccggcagcc
    29701 tctctcaaaa ccagcccgga actggcagag ttgttacgcc agcagcacag cgatgttcga
    29761 tcgagtcggc accttaataa agcgcactgg agtacggtct atctggacgg ctcgctgccg
    29821 gattcacaac tctattatct ggtcgatgcc tcttatcaac aggcggtaaa tgcgctgtcg
    29881 gaagataaac gcaagcagtt gccgcagtcc tgattatagc gcgccgacca acaacgccag
    29941 ggcgatatca atgaggtgga tgaccgtaga ccggatacgg ctgccgaggg caatttgcgc
    30001 attattggcg cgtagcctgg cgaggtcccg ctgtccttcc agcagaataa tcatatcgtc
    30061 gtcgtccagc cagccgcgag catgttcctg aagcgcgcgg gcgataaacg cggcggactc
    30121 gcggataccg tcgtcgctgt cttctcttgc ctgcttatac gtctggataa actcggcaat
    30181 tgccgaggag gctacaggat gttcggcccg ggcggcagta aacaggttac gtatttcgtt
    30241 aatagacgcc attttcttct ccctgagtgc agcgggcgcc ccaatgcaga cactcaccct
    30301 gtatggctaa tttccagacc tgattatttt gctgttggta tctctcagcc tggatgtaag
    30361 taagtggttg cttacatttc ataacccgcg cataaagacg caaatagtga tttttcagca
    30421 gcgccagatt atcgagtcgg tgtttatccc caccttgacg ggcgacccgc tcagcctgaa
    30481 aaaatgtctg gcggatatcg cggtcatctt tgagcagtgt ctctttttgc cacggtattc
    30541 gcgccgcgtc ctgcaggaag cgggttgagc gcgcttgtaa tagcgtcagt tgttgaaaag
    30601 ccacggcgct aaagcggtca ggcagcgtac aggcggctaa aaacaggcac agcagtagtg
    30661 tgattgcgta gggcaacttc atggtgtttt ccataacaga ccgtttgcgc tatcacatgt
    30721 cagagcgagg cggcacgcaa atcacaaatg ctcaacacgg atacaatgag gtgggatgag
    30781 gaaaaatgat gccgcttccc ggcgaatcgg aaagcggtgt gaaggttatt tgagcatagg
    30841 tttaaggaag cgggcggtat gcgacgcctc gcactccgcc acggtttccg gcgtaccggc
    30901 gacgagaatt tcgccgccgc cgctgccgcc ttccgggccg aggtcgacaa tccagtccgc
    30961 cgttttaatg acgtccaggt tgtgttcgat caccacgatg gtgttgccct gatcgcgcaa
    31021 ctgatgcagc acgtcaagca actgctgaat atcggcaaag tgcaggccgg tggtcggctc
    31081 gtcgagaata tacagcgtct gcccggtgcc acgtttcgac agttcgcgcg ccagcttcac
    31141 gcgctgggcc tcgccgccgg aaagcgtcgt cgccgactga ccaagacgga tataggtcag
    31201 ccccacgtcc atcagcgtct gcagcttacg cgccagcgcc ggaaccgcat caaagaactc
    31261 acgcgcttct tcaatggtca tatccagcac ttcgtggatg gtcttgcctt tgtacttaat
    31321 ctccagcgtt tcccggttat agcgcttgcc tttgcactgg tcgcacggca cgtaaatatc
    31381 cggcagaaag tgcatttcga ctttaatgac gccatcgccc tggcacgctt cgcagcgacc
    31441 gccgcgcacg ttgaagctga atcgccctgg cgtgtagccg cgcgagcgag actccggcac
    31501 gccagcaaaa agctcacgaa ccggggtaaa gacgcccgta taggtcgccg ggttggaacg
    31561 cggggtgcgc ccgatcgggc tctggtcgat atcgatcact ttatcgaaat gttccagccc
    31621 ctgaatatcc cgatacggcg ccggttcggc gatagtcgcc ccgtttaact gacgctgggc
    31681 gatggggaac agcgtatcgt taatcagcgt cgatttaccg gaacccgaga cgccggtgat
    31741 acaggtaaac agccctaccg gtagcgtaag ggtcacatct ttcaggttgt tgccgcgcgc
    31801 gccggtgagt ttgagcactt tttctggatt tgccggcacg cgttgtttcg gcacttcaat
    31861 tttgcgttta ccgctcatgt actggccggt cagcgattcc ggtaccgcca taatggcttc
    31921 cagcgggcct tccgccacca cctcgccgcc gtgaacgccc gcgccggggc caatatcaat
    31981 cacatggtcg gcggcgcgga tggcgtcttc atcgtgttcc accacaatca cggtattgcc
    32041 aagattgcgc agatgaatca gcgtacccag cagccgttcg ttatcgcgct ggtgcagacc
    32101 gatggacggt tcatccagca catacatcac gccgactaac ccggcgccta tctggctcgc
    32161 cagacgaata cgctgggctt cgccgccgga aagcgtctct gccgagcggg agagcgtgag
    32221 atagttcagg ccgacgttca ccagaaactt gaggcgatcg ccgatctctt ttagcacttt
    32281 ttcggcgatt ttcgcccgtt gcccggaaag cttgagatta gtgaaaaaat ccatcgcatg
    32341 gccaatgctc atatcggaaa tagcaggcag cggcgtattt tccacaaata catggcgcgc
    32401 ttcgcgattc agtcgcgttc cttcacagct ggcgcagggg cgattactga tgaatttcgc
    32461 cagctcttcg cgcaccgcgc tggattccgt ctctttataa cggcgctcca tattatgcag
    32521 cacgccttcg aacggatggc ggcgcacgga ggtatcgccg cgatcgttca tatatttaaa
    32581 ttcgatgttc tctttgccgg aaccgtacag cacgactttg tgtacgttgg cgctgaggct
    32641 tgcccacggc gcatccacgt cgaacttata gtgttccgcc agcgacttga gcatttgaaa
    32701 gtagtaaaaa ttgcgacgat cccaaccacg aatcgcgccg cctgccagcg acaggtcggg
    32761 attctggatc acgcggtccg gatcgaaata ttgctgaacg ccgagcccgt cacaggtcgg
    32821 acaggcgcct gccgggttgt tgaacgagaa cagacgcggt tccagctcgc gcatactgta
    32881 gccgcaaatc gggcaggcaa aattggcgga gaacagaagc tcctccgctt tctcatcgtc
    32941 catatcggca acaaccgccg tgccgccgga taattccagc gccgtttcga acgactccgc
    33001 caggcgttgg gaaagatcgt tacgaacttt gaagcgatcg atcaccacct caatggtatg
    33061 tttcttttgt agctccagct tcggcggatc ggagagatcg cagacttcgc cgtcaatacg
    33121 ggcgcgaatg taaccctggc ttgccagatt ttccagcgtt ttggtgtgtt cgcctttacg
    33181 ctctttaata atcggcgcca gcagcatcag gcgtttgcct tccggctgcg acagcacgtt
    33241 atcgaccatc tggctaacgg tttgcgccgc cagcggcacg tcatggtccg gacaacgcgg
    33301 ctcgcccacg cgggcaaaca gcaggcgcag gtagtcgtgg atctcggtaa tagtacccac
    33361 cgtagagcgc gggttgtgcg atgtcgattt ctgttcaatt gagatcgcgg gcgatagccc
    33421 ctcaatatgg tcgacatccg gtttttccat gagcgacaaa aactgccgcg cgtaagcgga
    33481 gagcgattca acgtaacgac gctgcccttc ggcatacaga gtgtcgaaag ccagtgagga
    33541 tttgcctgaa cccgaaagcc cggtcacgac aatcagtttg tcgcggggga tgacgaggtt
    33601 aatatttttg agattatggg tgcgggcgcc ccgaacttcg atcttatcca ttcacctttc
    33661 ccggtagaga ctcggatgcc tggtttgttt gaaggacaaa cggcagaaac ggctaattat
    33721 gacacaattt aacctgtttg aatatacagt attggaatgc atcttcagct aaagtatgca
    33781 acaatatgag gttcgcgcga gtgacctgga acctgcatcg cagctattaa aatgctacgt
    33841 ggaaatggta cactcacgcg tttacactat ttatgaaacg tattcaggag actcaattat
    33901 ggccagcaga ggcgtaaaca aggtgattct cgttggtaat ctgggccagg acccggaagt
    33961 acgctatatg ccgagtggcg gcgctgtcgc caacttaacg ctggctactt ctgaatcctg
    34021 gcgcgataag cagaccggcg aaatgaaaga gcagactgaa tggcaccggg tggtgatgtt
    34081 cggcaaactg gcggaagtgg ccggcgaata tctgcgtaaa ggttctcagg tgtatatcga
    34141 aggtcaattg cgtacccgca agtggaccga tcagagtggc caggaacgct atacgactga
    34201 aattaacgtt ccgcagatcg gcggcgtgat gcagatgctg ggtggtcgcc agggcggcgg
    34261 cgcaccggca ggcggtcagc agcagggggg ttggggtcag ccgcaacaac ctcagcagcc
    34321 gcagggcggt aaccagttca gcggcggcgc gcagtcgcgt ccacagcaat ccgcgccagc
    34381 gccgtctaac gaaccgccaa tggattttga cgacgacatt ccgttctgat ttttggtaaa
    34441 aaactcaaag cgttatttgc attttcgcta tagttctcgt ctgctgaaat gcctggtgta
    34501 aaccaggcat tttattacct ggtattattg tcttagtatc cctttcaaaa aagagaagcg
    34561 catatctcac ggaatgactt acggaaaaat gtcgcttatc gcctctggcc gactcgcctc
    34621 ggcacatcat tatccagccg aagttcataa atgtactgca ataacccgga ttgtcttaaa
    34681 tatgaaagag aaatctcatc tgcaaaatat ataatttata gccatttttt gacaacaaaa
    34741 agatattata aaataacggt agagaatggt cggtattatc aatagttaat taaatgctt
//
LOCUS       DAJVKX010000038        33421 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000038 DAJVKX010000000
VERSION     DAJVKX010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 33421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33421
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.038"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            80..727
                     /locus_tag="OPY25_001840"
     CDS             80..727
                     /locus_tag="OPY25_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCS0927471.1"
                     /translation="MMQNQHEGCCKNQDHKHDGCCKDREHQHEGCHSAHQHENASCGG
                     EHRHGHGCGRHGQGGGRRQRFFGHGELRLVILDILTRDASHGYELIKAIENLTGGGYT
                     PSAGVIYPTLDFLQDRQFITISDEEGGRKKIAITANGAQWLDENREHLTHIQARLKAR
                     CVGMELRKNPQMKRALDNFKAVLDLRINHSDINDAQIKRIIGVIDRAALEIAELD"
     gene            complement(724..2292)
                     /locus_tag="OPY25_001841"
     CDS             complement(724..2292)
                     /locus_tag="OPY25_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MCP four helix bundle domain-containing protein"
                     /protein_id="HCS0927472.1"
                     /translation="MFLHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQDI
                     ITNDYPTTVKANLLIDNFNDFIIAQQLMLLDEEGRWSQSSQKELSEISQRISALLDEL
                     SRENSHDADSQKIINEIREARQQYLESRFRILKDIQSNNRQAAIQEMMTRTVQVQKVY
                     KDKVQELIAVQDALMHEASVQVKEDFKNNRTLLITLALISIAAGGVIGWYIVRSITRP
                     LDDAVRFAEAIADGDLTRHITTDYKDETGVLLQALMAMKTRLLDIVQEVQNGSESIST
                     AAAQIVAGNQDLAARTEEQASSVEETAASMEQITATVKNTADHTSEATKLSAGAASVV
                     KNNGEMMNQVTQKMRVINDTANRMSDIINIIDSIAFQTNILALNAAVEAARAGEHGRG
                     FAVVAGEVRQLAQKSASSASEIRNLIEDSTSQTQEGMHLVEKASALINGMVDNVEEMD
                     VILREIGQASREQTDGISQINSAIGLIDAATQQNSCLVEESVAAAASLNEQALHLKEL
                     VNVFRVREEDTQPA"
     gene            complement(2680..4200)
                     /locus_tag="OPY25_001842"
     CDS             complement(2680..4200)
                     /locus_tag="OPY25_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCS0927473.1"
                     /translation="MSSHPYVSQLNTPLDDDTTLMSTTDLESYITHANDTFVQVSGYQ
                     LNELLARPHNLVRHPDMPKAAFADMWYTLKQGEPWSGIVKNRRKNGDHYWVRANAVPM
                     IREGRVTGYMSIRTRATDDEIAAVEPLYQALNEGRCSKRIHKGLVVRQGLLGKLPAMP
                     VRWRVRSIMGLMAVMLALALFGTDASWQALLLGALAMLAGTALFEWQIVRPIENVATQ
                     ALKVATGERNSVQHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSERLAK
                     GNNDLNEHTRQTVENVQETVTTMNQMAESVKLNSETASAADKLSMAASSAATQGGEAM
                     DTVIKTMDDIAHSTQRIGTITTLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASATKVQSGSEQVHAAGRTMDDIVAQVQNVTLLIARIS
                     QSTQEQTDGLSSLTRAVDELNRITQKNAALVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            4630..6009
                     /gene="ygjG"
                     /locus_tag="OPY25_001843"
     CDS             4630..6009
                     /gene="ygjG"
                     /locus_tag="OPY25_001843"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HCS0927474.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAM
                     SMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPNLVHEARGKGMLMA
                     IEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALA
                     AMQVSVEEV"
     gene            6180..8197
                     /locus_tag="OPY25_001844"
                     /pseudo
     CDS             6180..8197
                     /locus_tag="OPY25_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
     gene            complement(8278..9414)
                     /gene="rlmG"
                     /locus_tag="OPY25_001845"
     CDS             complement(8278..9414)
                     /gene="rlmG"
                     /locus_tag="OPY25_001845"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HCS0927475.1"
                     /translation="MSHVDDGFRSLTLKRFPQTDDVNPLLAWEAADEYLLQQLDETEI
                     RGPVLILNDTFGALSCALAEHSPYSIGDSYLSELGTRENLRHNGIAESSVTFLDSTAD
                     YPQAPGVVLIKVPKTLALLEQQLRALRKVVTAQTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFSHPQLANAPQTLSWKLEDTGWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLDGEIVDLGCGNGVIGLSLLAKNPQANVVFVDESPMAVDSSRLNVETNL
                     PEAFERCEFMINNALSGVEPFRFNAVFCNPPFHQKHALTDNIAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCATIATNNKFVILKAVKQGRRR"
     gene            9500..9997
                     /locus_tag="OPY25_001846"
     CDS             9500..9997
                     /locus_tag="OPY25_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HCS0927476.1"
                     /translation="MTSLTYLQGYPEHLLAQVRALIAEQRLGAVLEKRYPGAHDYATD
                     KALYHYTQELKSQFLRNAPPINKVMYDSKIHVLKNALGLHTAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKDHNKAFYQLCCHMEPQYHQLEFDTRLWLTHQ
                     ALSAQ"
     gene            10149..10841
                     /locus_tag="OPY25_001847"
     CDS             10149..10841
                     /locus_tag="OPY25_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HCS0927477.1"
                     /translation="MLSQCARFIRRLCFTRRALTVACFLLVAAGVALFYSNWLIVNAS
                     QHLTWNDIQTVPARNVGLVLGAKPGNRYFTRRINTAAALYHAGKVKWLLVSGDNGKKE
                     YDEPSAMQQALIAKGVPEAAIFCDYAGFSTLDSVVRARKVFGESRITIISQAFHNQRA
                     IWLAQQYGIDAIGVNAPDLNKRHGTYTRLREKLARVSAVLDAKILHRQPKYLGAGVTI
                     GADSAHGCPSRQ"
     gene            10929..11927
                     /locus_tag="OPY25_001848"
     CDS             10929..11927
                     /locus_tag="OPY25_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCS0927478.1"
                     /translation="MIRFAVIGTNWITRQFVDAAHETGKFRLAAVYSRRLEQAQSFAN
                     DYPVEHLFTSLEAMAQSDAIEAVYIASPNSLHFSQTQRFLQHKKHVMCEKPLASNLAE
                     VDAAIACARDNQRVLFEAFKTACLPNFLLLRESLPKIGRMHKALLNYCQYSSRYQRYL
                     NGENPNTFNPAFSNGSIMDIGYYCLASAIALWGEPRSVQASANLLESGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGERGSLVIEKLSECQKVCFAPRGALMQDLTQPQHI
                     NTMLYEAGAFAQLIENHAVEHPGLSLSRATAKWLTEIRRQTGVIFPADDLTHPPTA"
     gene            12195..13163
                     /locus_tag="OPY25_001849"
     CDS             12195..13163
                     /locus_tag="OPY25_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HCS0927479.1"
                     /translation="MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGW
                     SILWVTLSLLFNAAFWWYLAETQGREVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPPALQRRVLVYGVLGAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMAL
                     AKEDESGIGEKPMVRWLRGHLRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAISLGVVFGILTITLVINTWVNHQRDKKLRAQ"
     gene            13418..14662
                     /gene="sstT"
                     /locus_tag="OPY25_001850"
     CDS             13418..14662
                     /gene="sstT"
                     /locus_tag="OPY25_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCS0927480.1"
                     /translation="MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPVAEAVG
                     LLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVF
                     SFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPVGIFGLVSSTLATTGFSTLWGYAHL
                     LVVLIGCMLLVALVVNPLLVFWKIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDERLANNALRS"
     gene            15112..15774
                     /locus_tag="OPY25_001851"
     CDS             15112..15774
                     /locus_tag="OPY25_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCS0927481.1"
                     /translation="MELLTQLLNALWAQDFETLANPSMIGMLYFVLFMILFLENGLLP
                     AAFLPGDSLLILVGVLIAKGAMGFPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGISGLNNARFQFFNWMS
                     GLLWVLILTSLGYLLGKTPVFMKYEDQLMSCLMLLPVVLLFFGLAGSLVMLWKKKYGS
                     RG"
     gene            15778..16161
                     /gene="mzrA"
                     /locus_tag="OPY25_001852"
     CDS             15778..16161
                     /gene="mzrA"
                     /locus_tag="OPY25_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HCS0927482.1"
                     /translation="MLKPRITARQLIWISAFLLMLTILMMTWSTLRQQESTLAIRAVN
                     QGASMPDGFSVLHHLDANGIHFKSITPKNDMLLITFDSPAQSAAAKTVLDQTLPHGYV
                     VAQQDDDNETVQWLSRLRESSHRFG"
     gene            16306..16674
                     /locus_tag="OPY25_001853"
     CDS             16306..16674
                     /locus_tag="OPY25_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HCS0927483.1"
                     /translation="MKYRIALAITLFTLSAGSYANSLCQEKEQDIQKEISYAEKHNNQ
                     RRIEGLNKALSEVRANCTDSKLRAEHQKKIAEQKEEVAERQRDLAEAKAKGDADKIDK
                     RERKLAEAQDELKKLEARDY"
     gene            16716..17021
                     /locus_tag="OPY25_001854"
     CDS             16716..17021
                     /locus_tag="OPY25_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HCS0927484.1"
                     /translation="MSKDNTTEHLRAELKSLTDTLEEVLSSSGEKSKEELSKIRSKAE
                     RALKESRYRLGETGDVIAKQTRVAAARADDYVRENPWTGVGIGAAVGLVLGVLLTRR"
     gene            17024..17422
                     /locus_tag="OPY25_001855"
     CDS             17024..17422
                     /locus_tag="OPY25_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCS0927485.1"
                     /translation="MADSRQAQGPGKSVLGIGQRIVTIIVEMVETRLRLAVVELEEEK
                     ANLFQLLLMVGLTMLFAAFGLMSLMVLVIWAIDPQYRLNAMIATTVVLLVLALIGGIW
                     TLRKARQSTLLRHTRHELANDRQILEDDQS"
     gene            17419..17718
                     /locus_tag="OPY25_001856"
     CDS             17419..17718
                     /locus_tag="OPY25_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HCS0927486.1"
                     /translation="MSSKGEREKRKALLLSQIQQQRLDLSASRRDWLETTGAYDRGWN
                     TVLSLRSWALVGSSVMAIWTIRHPNMLVRWAKRGLGIWSAWRLVKTTLRQQQLRG"
     gene            17966..18358
                     /locus_tag="OPY25_001857"
     CDS             17966..18358
                     /locus_tag="OPY25_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HCS0927487.1"
                     /translation="MKKLEDIGVLIARILMPVLFITAGWGKISGYAGTQQYMEAMGVP
                     GFLLPLTILLEFGGGLAILLGFLTRTTALFTAGFTLLTALIFHSNFAEGVNSLMFMKN
                     LTIAGGFLLLALTGPGAFSLDRLLNKKW"
     gene            18426..19412
                     /locus_tag="OPY25_001858"
     CDS             18426..19412
                     /locus_tag="OPY25_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HCS0927488.1"
                     /translation="MGQLIDGVWHDTWYDTKSSGGKFQRSASAFRNWLTADGAPGPSG
                     EGGFAAEKDRYHLYVSLACPWAHRTLIFRKLKGLEPFIPVSVVNPLMLENGWTFDDTF
                     PAATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNSAF
                     DGLGAKAGDYYPPALQSKIDELNGWIYDNVNNGVYKAGFATSQQAYDEAVEKVFTALA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKYRISDYLNLYGFLRD
                     IYQIPGIAETVNMDHIRHHYFRSHKTINPTGIISVGPWQDLLEPHGHDVRFG"
     gene            19536..19901
                     /locus_tag="OPY25_001859"
     CDS             19536..19901
                     /locus_tag="OPY25_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HCS0927489.1"
                     /translation="MDWYLKVLKNYLGFGGRARRKEYWMFILVNIIFTFVLGLLDAML
                     GWQRAGGEGVLTTIYGVLIFLPWWAVQFRRLHDTDRSAWWLLLLLIPIIGWLIIIAFN
                     CQNGTPGDNRFGPDPKRFS"
     gene            complement(19940..20836)
                     /gene="yhaJ"
                     /locus_tag="OPY25_001860"
     CDS             complement(19940..20836)
                     /gene="yhaJ"
                     /locus_tag="OPY25_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HCS0927490.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTLV
                     TEALVPTPAFFPLIDRLAAKANTQLSLITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHSIHQEPEPLSEVTRVKYRGVAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYSMVEQDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKAWCLREIPKLFAGK"
     gene            20941..21642
                     /locus_tag="OPY25_001861"
     CDS             20941..21642
                     /locus_tag="OPY25_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HCS0927491.1"
                     /translation="MITTRTAKQCGQADYGWLQARYTFSFGHYFDPTLLGYASLRVLN
                     QEVLAPGASFQPRTYPKVDILNLILDGEAEYRDSDGNHVQAKAGEALLLAAQPGISYS
                     EHNLSKVKPLTRMQLWLDACPERENALVQKIPLSTAQQQLLASPDGEQNSLQLRQQVW
                     VHHITLEKGESLNFQLHGPRAYLQSIHGTFHAMTHNEEREALTCGDGAFIRDEPNITL
                     VADTPLRALLVDLPV"
     gene            21666..21830
                     /locus_tag="OPY25_001862"
     CDS             21666..21830
                     /locus_tag="OPY25_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927492.1"
                     /translation="MSKKSAKKRQPVVKPAVQEAMSAAVPLGYEEMLTELEAIVADAE
                     ARLAEEEAAA"
     gene            complement(21943..23253)
                     /locus_tag="OPY25_001863"
     CDS             complement(21943..23253)
                     /locus_tag="OPY25_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HCS0927493.1"
                     /translation="MFESKINPLWQSFILAVQEEVKPALGCTEPISLALAAAAAAAEL
                     DGTVERIDAWVSPNLMKNGMGVTVPGTGMVGLPIAAALGALGGDAKAGLEVLKDASAK
                     AVADAKAMLAAGHVAVMLQEPCNDILFSRAKVYSGDSWACVTIVGDHTNIVRIETDKG
                     VVFTQADNAQEEEKTSPLGVLSHTSLEEILAFVNAVPFDAIRFILDAARLNGALSQEG
                     LRGSWGLHIGSTLAKQCDRGLLAKDLSTAILIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATVPVMVVAEHVGADDECLARALMLSHLSAIYIHHQLPRLSALCAATTAAMGAAA
                     GMAWLIDGRYDTIAMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHNVEQSISNLCSLACRSMQQTDKQIIEIMASKAH"
     gene            complement(23279..24231)
                     /locus_tag="OPY25_001864"
                     /pseudo
     CDS             complement(23279..24231)
                     /locus_tag="OPY25_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985932.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation protein"
     gene            complement(24331..24609)
                     /locus_tag="OPY25_001865"
                     /pseudo
     CDS             complement(24331..24609)
                     /locus_tag="OPY25_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985905.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24924..26288)
                     /gene="tdcG"
                     /locus_tag="OPY25_001866"
     CDS             complement(24924..26288)
                     /gene="tdcG"
                     /locus_tag="OPY25_001866"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HCS0927494.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKCFIDRLIDSGDLPRTTR
                     ITVDLYGSLSLTGKGHATDTAIIMGLAGNTPQDVNIDSIPAFIQEVARSSRLSVAGGA
                     HVVDFPVADSILFHAETLARHENGMRITAWHGQTPLLHKTYYSIGGGFIVEEERFGQS
                     HDVEKSVPYDFHSASELLTLCERQGLSVSGLMMQNELALRSKEQIDAGFARIWQVMAT
                     GIERGMNTEGVLPGPLNVPRRAVALRRLLVSSDNLSRDPMNVIDWINMFALAVSEENA
                     AGGRVVTALTNGACGIIPAVLAYYDKFRRPVNANSIARYLLSAGAIGMLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLTELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMALRRTSEPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(26358..28652)
                     /gene="pflB"
                     /locus_tag="OPY25_001867"
     CDS             complement(26358..28652)
                     /gene="pflB"
                     /locus_tag="OPY25_001867"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCS0927495.1"
                     /translation="MKVNIDTSDMLYAEAWRDFKGTDWKEEINVCDFIQHNYTPYEGD
                     ESFLADATPATTALWEKVMAGIRIENATHAPVDFDTNIATTITAHDAGYIEKELEKIV
                     GLQTDKPLKRALHPFGGVNMIKSSFHAYGREMDADFEYTFTDLRKTHNQGVFDVYSPD
                     MLRCRKSSVLTGLPDGYGRGRIIGDYRRVALYGIRYLVRERELQFADLQSNLERGQNL
                     EATIRLREELAEHRRALLQMQEMAAKYGYDISRPARNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFNAGLLTEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEALPVAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLTDEVLDYDAVMESLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVAADSLSAIRYAQVKPIRDENGLAIDFAIEG
                     EYPQYGNNDERVDSIACDLVKRFMQKISVLPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DAVRKTNLVGLLDGYFHHEAQVEGGQHLNVNVMNREMLLDAIEHPENYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAM"
     gene            complement(28686..29894)
                     /gene="tdcD"
                     /locus_tag="OPY25_001868"
     CDS             complement(28686..29894)
                     /gene="tdcD"
                     /locus_tag="OPY25_001868"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HCS0927496.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDVATCDVLMAGIADGMNTENAF
                     LSINGDKPINLSHSNYEDALKAIAFELEKRDLTDSVALIGHRIAHDGELFTQSVIITD
                     EIIDNIRRVSPLAPLHNYANLSGIDAARRLFPAVRQVAVFDTSFHQTLAPEAYLYGLP
                     WEYFSSLGVRRYGFHGTSHRYVSRRAYELLDLDEKNSGLIVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMAWIAKETGQTLSDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERARLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSVLI
                     RQLVIEHLGVLGLTLDVEMNKQPNSHGERIISVNPSQVICAVIPTNEEKMIALDAIHL
                     GNVKAPVEFA"
     gene            complement(29961..31291)
                     /gene="tdcC"
                     /locus_tag="OPY25_001869"
                     /pseudo
     CDS             complement(29961..31291)
                     /gene="tdcC"
                     /locus_tag="OPY25_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462157.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
     gene            complement(31312..32301)
                     /gene="tdcB"
                     /locus_tag="OPY25_001870"
     CDS             complement(31312..32301)
                     /gene="tdcB"
                     /locus_tag="OPY25_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HCS0927497.1"
                     /translation="MHITYDLPVAIEDILEAKKRLAGKIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTEAEKRKGVVACSTGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVETEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAIAIKSINPTIKVIGVQAENVHGMAA
                     SYYAGEITAHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVITEGAGALACAALLSGKLDSHIQNRKTVSIISGGNIDLSRVSQITGLVDA"
     gene            complement(32399..33337)
                     /gene="tdcA"
                     /locus_tag="OPY25_001871"
     CDS             complement(32399..33337)
                     /gene="tdcA"
                     /locus_tag="OPY25_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HCS0927498.1"
                     /translation="MNTLVLPKTQHLVVFQEVIRSGSIGSAAKSLGLTQPAVSKIISD
                     VEAYFGVELIVRKNTGVTLTEAGQVLLSWSESITREMKNMINEMNSMTCNTVVDVSFG
                     FPSLIGFTFMSDMIHKFKEVFPKAQVSMYEAQLSSFLPALRDGRLDFAIGTLSNEMQL
                     QDLHVEPLFESEFVLVASKSRTCTGTITLESLKDEQWALPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTTPFGSNQFITIPIKDTLPVARYAAV
                     WSKNYRIKKAASVLVELAKQYSSYNGCRRRQLIEIE"
BASE COUNT         8001 a         9036 c         8416 g         7968 t
ORIGIN      
        1 tatagcaaaa atggctttta cccttgctaa aacccatcat ttagatataa attagatata
       61 tctaaataag caggagacaa tgatgcaaaa tcaacatgaa gggtgttgca aaaaccagga
      121 tcataagcac gacggctgct gtaaagatcg agaacatcag catgaaggct gccatagcgc
      181 gcatcagcat gagaacgcca gttgcggcgg cgaacatcgt cacggacacg gctgtggtcg
      241 tcatggacag ggcggtggtc ggcgtcagcg attttttggc cacggggaac ttcggctggt
      301 cattcttgat atcctgaccc gggacgccag ccacggctat gaactgatta aagcgataga
      361 aaacctgacg gggggcggct atacgccaag cgctggcgtg atctacccta cgctggattt
      421 tttacaggat cggcaattta tcacgattag cgacgaagaa ggcgggcgga aaaaaatcgc
      481 gattaccgcg aacggcgcgc aatggcttga tgaaaatcgc gaacatctga cgcatattca
      541 ggcgcggcta aaagcccgtt gtgtgggcat ggagttacgt aaaaatcctc agatgaagcg
      601 ggcgctggat aacttcaagg ccgtgctgga tctgcggata aaccacagcg atatcaacga
      661 cgcgcaaatc aaacgcatta tcggcgtgat tgatcgcgcg gcgctggaaa tcgccgaact
      721 ggattaagcg ggctgcgtgt cctcttcgcg gacgcggaac acgttaacca gctcttttaa
      781 atgtaacgcc tgttcgttca gcgacgctgc ggcggcaaca gactcttcca caaggcagga
      841 gttttgttgc gtggcggcgt caatcaggcc aatcgcgctg ttaatctgcg aaataccgtc
      901 agtttgctcg cggctggcct gcccaatctc acgtaatatc acatccatct cttcgacgtt
      961 gtccaccatg ccattaatca gggcgctggc tttctccacc aggtgcatcc cttcctgagt
     1021 ctgactggtt gaatcttcaa tcaaattacg gatttcactg gccgacgagg cgctcttttg
     1081 cgccaactgg cgaacctctc cggcgacaac ggcaaaaccg cgcccatgtt cgcccgcgcg
     1141 cgccgcttca accgccgcgt tcagcgccag aatattggtc tgaaaggcaa tggaatcaat
     1201 gatattgatg atatccgaca tacgatttgc cgtatcgtta atgacgcgca ttttctgcgt
     1261 cacttgattc atcatctccc cattgttttt cactacgctg gcggcgccag cagagagttt
     1321 ggtcgcttca ctggtatgat cggctgtgtt tttaaccgtg gcggtaatct gttccatcga
     1381 cgccgccgtt tcttcaaccg agctggcctg ctcttccgta cgcgccgcca aatcctggtt
     1441 accggcgaca atttgcgccg ccgccgtgga gatactctcc gaaccgtttt gcacttcctg
     1501 tacgatatcc agcagacgcg ttttcatcgc cattaacgct tgcagtagta cgcctgtttc
     1561 atctttatag tcggtggtga tatggcgagt cagatcgcca tcggcaatcg cctcggcaaa
     1621 gcgtaccgcg tcatcaagcg gtcgggtaat agaacgcaca atataccatc ctattacgcc
     1681 tccggcggcg atgcttatca gcgccaaagt gattaacaac gtccgattat ttttaaaatc
     1741 ctctttgacc tgcacgctcg cttcatgcat cagcgcgtcc tgaacagcga taagttcctg
     1801 gactttgtcc ttatagactt tttgcacctg caccgttctg gtcatcatct cctgaatggc
     1861 cgcctgacga ttattgcttt gaatatcttt caaaatacgg aatctggact ccaggtattg
     1921 ctggcgcgct tcacggattt cattaatgat tttctgtgaa tccgcatcgt gactattttc
     1981 cctggaaagc tcatccagta acgccgaaat gcgctggctt atctcactga gttctttctg
     2041 cgagctctgg ctccagcgcc cctcttcatc cagtaacatg agctgctgcg cgatgatgaa
     2101 atcattaaaa ttatcgatta acagattggc ttttaccgtg gtgggataat cattggtaat
     2161 aatgtcctgc atacccgtat tagcccgatc aaggctaaac aaagacagag cggaactcac
     2221 caccatgaga acaatgaata agccaaaggc cataaataat tttgaacgta ttttaatgtt
     2281 atgcaaaaac atattttctc cctgggatcg catatcctca tacaggaaga tttatcggca
     2341 ataatgttac taactttatg atattgatcg ctttttattt cggaacatta ttagtaatta
     2401 atatttattg ttcacagaaa gatgaaccaa aagtgacata aattggcact aataatgaaa
     2461 gaaatacgct aaaaggttaa ccatttctta tttatcaact gagtttatac ctattaatag
     2521 gtagacaagg gagaaggaat aaatatcaca ttatttttaa catcacaggc cactggtact
     2581 ctctatgatg gcaggcaccg ccttctatca gagcacatcc gcccggtaag cttgttgcta
     2641 ccgggcggat gtcattaccg ttgctaccta caaataaact taatgcagta ccgtgaccgc
     2701 atcctccagc cggctggcac ggtgttttac catcgcggag acttgtgcgc tctcttccac
     2761 cagcgccgca ttcttctggg ttatgcggtt caactcgtcc acggcgcgag tcaggctgga
     2821 aagcccatct gtctgttcct gcgtcgactg gctgatccgt gcgataagca gggtgacatt
     2881 ttgcacctgg gctacaatgt catccatggt acggcctgcg gcgtgaacct gctcggagcc
     2941 tgactgcacc tttgttgcgc tggcatcaat taatttacga atatcgttcg ccgcgttagc
     3001 gctgcggctg gcaagatggc gtacctcgcc agcaaccacg gcaaaccctt tcccctgctc
     3061 gcccgctctc gccgcttcta ccgccgcatt cagcgccagg atattcgtct gaaaagcgat
     3121 atcgttaatt agcgtggtga tcgtcccgat acgttgcgta ctgtgagcga tatcatccat
     3181 cgttttaatc accgtatcca tcgcctcacc tccctgagtc gccgcgctac tggccgccat
     3241 ggaaagctta tccgcagcgg aagccgtctc ggaattgagc ttcacggact ccgccatctg
     3301 gttcatggtc gttaccgttt cctgaacatt ctccacggtc tgacgggtgt gttcgttcag
     3361 atcattgtta cccttcgcca gcctttcact gccgtttctg acgctggaca cctgacttga
     3421 tacgtcattg atcagccaac ggcacatcaa gccaagctgc cccacggccc tcagcgtcag
     3481 ccccaactca tcgctacgat taaggtgttg tacgctgttg cgttcgccgg tcgccacttt
     3541 cagcgcctgc gtcgccacat tttcaatggg acgcacaatt tgccattcaa atagcgccgt
     3601 acctgccagc atcgccaacg cgcccaacaa caacgcctgc catgaggcat ccgtaccgaa
     3661 cagcgccaac gccagcatta cggccattag ccccataatg ctacgcactc gccagcgaac
     3721 aggcatcgcg ggcagtttgc ccagcaagcc ctgacgaacc accaggcctt tatgaatacg
     3781 tttactacac cgcccttcat ttagcgcctg atataaaggc tcgacggcgg caatctcatc
     3841 atccgtggcg cgggtacgga tcgacatata tcccgtcaca cgcccttcac gtatcatcgg
     3901 taccgcgttg gcccgcaccc aataatgatc gccgttttta cgccggtttt tcacaatgcc
     3961 gctccacggt tcgccctgtt ttagggtgta ccacatatct gcgaaggcag ctttcggcat
     4021 atccggatga cgcaccagat tatgtggccg cgccagtaac tcgtttaact gatagccgct
     4081 cacctggaca aaagtgtcat tggcgtgagt gatatagctt tccaggtcgg tcgtagacat
     4141 cagagtggta tcatcatcca gcggggtatt tagctggctg acgtagggat gagaagacat
     4201 gatagcgtcc tgtgcaggtt atctggatgt taatttttcg ctcagatgtt atttcggcgc
     4261 taatctattt atctttagtt gttaaaattg ctctggatcg caatttgcga ttaatcctta
     4321 atatttgtac gattttcacc ttatcctgcg ccttattttc attatgaaat tgtttagcgt
     4381 ggacaacctt tttctttaaa atctgccctg gctcaccttt ttctcacgcc gccgctaacg
     4441 caacacaccg taaaccgtaa aacaagatct gctcaaaatg catccaattg ttaacgtata
     4501 acattaaatg ttgtgtaaat gtgattattc ctggtgttta tcccgatttt cactatgggc
     4561 ttagaccccc gctaatccct gcaatactta attcagtatc atgtgataca cggccctctg
     4621 gagctcattt tgaacaggtt accttccagc gcatcggctt tggcctgtag cgcgcacgca
     4681 ctgaatctca tcgagaagcg aacgctaaac catgaggaaa tgaaagcact aaaccgagag
     4741 gtcattgact actttaaaga gcatgtaaat ccaggatttc tggaataccg gaaatctgtt
     4801 accgccggcg gggattacgg agccgtagag tggcaagcgg gcagtttgaa tacgcttgtc
     4861 gacacccagg ggcaggagtt tatcgattgt cttggggggt ttggcatctt taacgtgggg
     4921 caccgtaatc ctgttgtggt atccgccgtc cagaatcaac tcgcaaaaca acctctccac
     4981 agccaggagt tacttgaccc cttgcgggcg atgctggcaa aaacgctggc ggcgctaaca
     5041 ccggggaaac tcaagtacag ctttttctgt aacagcggca ccgaatccgt cgaagcggcg
     5101 ctaaaactgg caaaagcgta tcagtcgccg cgcggcaagt ttacctttat cgccaccagc
     5161 ggcgcatttc acggcaaatc attgggcgcg ctctccgcca cggccaaatc caccttccgc
     5221 agacccttta tgcctttact gccgggcttc cgccatgtgc cgtttggcaa tatcgacgcg
     5281 atgagcatgg catttagcga aggcaaaaaa acgggcgacg agatagcagc cgtgattctg
     5341 gagcctattc agggtgaagg cggcgtgatc ctgccgccgc agggatacct gacagaggta
     5401 cgtaagctct gtgatgaatt cggcgcgctg atgattctgg atgaagtaca aaccggcatg
     5461 gggcgtaccg gcaagatgtt tgcctgcgag cacgaaaatg tgcagcctga tattctgtgt
     5521 ctggcgaaag ccctgggcgg cggcgtgatg ccaattggcg ccaccatcgc gactgaggag
     5581 gtgttttcgg ttctgttcga caatcccttc ctgcatacca ccacttttgg cggtaacccg
     5641 ctggcttgtg ctgccgcgct ggcgaccatt aacgtcctgc tggaacaaaa cctcccggcc
     5701 caggcggaac aaaaaggcga tacgctcctg gatggttttc gacaacttgc gcgtgaatat
     5761 cccaatctgg tacacgaggc gcgcggcaaa ggtatgttga tggccattga atttgtcgat
     5821 aacgaaacgg gctaccgttt tgccagtgag atgttccgtc aacgcgtgct ggtcgctggt
     5881 acgctgaata atgcgaaaac aattcgtatc gagccaccgc tcacgctaac cattgaactg
     5941 tgcgaacagg tattgaaatc agcgcgtaat gcgctggcgg caatgcaggt gagcgttgaa
     6001 gaggtttaaa aacgatgccg gatggcgctg tgcttatccg gcctgttttc cccgggtcgc
     6061 ggcctctttt ttgaatccca tcacaatcac cacattcccc ttttcccttt tacctcgcga
     6121 cggctacagt agtaactcat ccgaccacat aacaataatt ttacatactg gatacgctta
     6181 tgagctaccc gtcgctgttc gccccgctcg atctgggctt tactactctc agaaaccgtg
     6241 tgctgatggg atcgatgcac acgggtctgg aagaacatcc tgatggcgct gagcgcctgg
     6301 cggcatttta tgccgagcgc gcgcgacacg gcgtagcgtt aatcgtcacc ggcggtattg
     6361 cgcccgttcc ctccggggtc gtgatgaccg gcggcgcgat gctgaacgat gccagccagt
     6421 taaagcctca ccgcgtggtg accgatgccg tacatgcgca aggcggtaaa atcgcgctgc
     6481 aaattctgca caccggacgt tacagctatc agccgcacct ggtcgcgccg tcggcaattc
     6541 aggcgccaat caaccgcttt atgccacatg aactgacgca tgatgaaatc ttgcagttaa
     6601 tcgacgactt cgcacattgc gcgcagctgg cgcgggaagc aggctacgac ggcgtagagg
     6661 tgatgggatc agagggctat ctgattaatg aatttctcac gcggcgaact aaccatcgcg
     6721 atgacgaatg gggcggcgac tataccagtc gtatgcgctt cgcggttgag gtagtacgcg
     6781 cggtacgcca gcgggtaggg aacgacttta ttattatcta tcgcctgtcg atgctcgatc
     6841 tggtggaaaa tggcggcacg ttcgacgaaa cggtacaact ggcgcaagcc attgaagccg
     6901 caggcgcaag cctaattaat accggcattg gctggcatga ggcgcgaatc ccgaccatcg
     6961 ccacgccagt accgcgtggc gcctttagct gggtgacacg gaaactcaaa ggtcatgtgt
     7021 cggttccgct gatcgcgacc aatcgcatta acgatccgca ggtcgccgag acgatcctga
     7081 cgcgcggcga tgccgatatg gtgtcgatgg cgcgtccctt ccttgccgat gctgaattcc
     7141 tgactaaagc gcaatccgga cgcgcagatg agatcaatac ctgtatcggc tgtaatcagg
     7201 cctgtctgga tcggatcttc atcggcaaag tgacctcctg tctggtgacc cacgcgcctg
     7261 tcacgaaacc cacatgccga taacgccggc catacgcaaa aagaatctgg ccgttgtcgg
     7321 cgcaggcccg gcggggctgg ctttcgcgat taacgccgcg tcgcgcggcc atcatgtcac
     7381 gctgtttgac gcccagagtg aaattggcgg tcagtttact atcgccaggc agatcccggg
     7441 taaagaagag ttttacgaaa cgctgcgcta ctaccgtcga atgatcgatg ttactggcgt
     7501 tacgctgaaa ctgaaccaac gggtgaacgc agaggatctt cagccgtttg acgaagcgat
     7561 cctcgcctgt ggaatagtac cgcgccgccc gccgatagac ggtatcgatc atccaaaagt
     7621 attgacctac ctggaggtat tgcgcgataa agcgccggtt ggtaagcgag tggcgatcat
     7681 cggctgcggc gggatcggtt ttgacacggc catgtatctg agccagcacg gcgaatccac
     7741 cagccaaaat attgctgaat tttgtacgga atggggaatt gataccagcc tgcaacaggc
     7801 aggcggtctg cgcccggaag gcccgcgcct ggcacgtagt ccacggcaaa tcgtcatgct
     7861 gcaacgcaaa gccagcaagc cgggcgaagg gttaggtaaa accaccggct ggatccatcg
     7921 cgcgacgtta ctggcgcgcg gcgtgaagat gatcccggcg gtcagttact agaagatcga
     7981 cgacgacgga ttacatctct tgatcggcgg cgaaccgcag ttgctggaag tggatcatgt
     8041 ggtgatctgc gccggacagg aaccccgccg tgaactggcg gacccgttac gcgccgcagg
     8101 taaaacggta catcttatcg gcggatgcga tgtcgcgatg gaactggatg cccgacgggc
     8161 gattgcccag ggcacccgac tggcgctgga gatttaacga ctttgcctga tggcgctgcg
     8221 cttatcgggc ctatgccgtc ataccggttt tataggccgg tatgacgctt gagtgcctta
     8281 tcgacggcgt ccctgcttca ccgctttcag aataacaaat ttattgttgg ttgctatcgt
     8341 cgcgcaatta ccgaaaatct tcttcagctt gtggaaatag tccagatggc ggttcgccac
     8401 aatatacagt tcgccgttga ttttcaggca gcggcgggca tgatggaaca tctcccaggc
     8461 gatattatcc gtcagcgcat gtttctggtg gaacggcgga ttgcagaaca ccgcgttaaa
     8521 acggaacggc tccacgccgg agagcgcgtt gttgatcata aattcgcagc gttcgaacgc
     8581 ttccggcagg ttcgtttcta cattcaaacg gctggaatct accgccatcg gcgattcatc
     8641 gacaaatacc acgttcgcct gcggattttt cgccagtaag ctcaggccaa tcaccccatt
     8701 gccgcagccg agatcgacaa tctccccgtc gaggttttcc ggcaaatgct gcataaagaa
     8761 gcgcgcgccg atatccaatc cggtacgaga aaacacattc gcgtggttgt gaatcgtcca
     8821 gcctgtatct tccagtttcc agcttagcgt ttgcggcgcg ttggccagtt gcggatgact
     8881 gaaggtacag ttaatcaggc gcgctttctt ccacgccagc gtcgtcgtgg ttgggcccag
     8941 cactttttca aacagttcca gcgtagaggt atgaatatca cgcgctttcg cgccggcgat
     9001 aatacgcgtt tgcgccgtaa cgaccttacg caaagcgcgt aactgctgtt ccagcaacgc
     9061 cagtgttttc ggtactttaa tcaataccac gcccggtgcc tgcgggtagt cagcggtact
     9121 gtcgagaaac gttacgctgg actccgcgat gccgttatgg cgtaaattct ctcgcgtacc
     9181 cagttcgctt aaatatgaat cgccaatact gtatggcgaa tgctccgcca gcgcacagct
     9241 tagcgcgcca aacgtatcat tcaggatcag caccgggccg cgaatttccg tctcatccaa
     9301 ctgttgcagc agatactcat cggccgcctc ccacgccaga agcgggttaa catcatccgt
     9361 ttgcggaaaa cgtttcagcg tcagtgaacg gaaaccgtcg tctacgtggc tcattaggcc
     9421 tcctgaatgg taaaattgcg gcgttatccc tgaaaagggt gcgtgagtat acacttttta
     9481 tcggcaacat ggagctttga tgacctcact aacttacctt caggggtatc cggaacatct
     9541 ccttgcccag gtgcgcgcct taatcgccga gcagcgcctg ggggcggtgc tggaaaaacg
     9601 ttatcccggc gcgcatgatt acgctactga caaagcgcta tatcactata ctcaggaact
     9661 gaaaagtcag tttctgcgca atgcgccgcc catcaataaa gtgatgtatg acagcaagat
     9721 ccatgtgctg aaaaatgcgc tgggactgca taccgctgtc tcgcgcgttc agggcggcaa
     9781 gctcaaggcc aaggcggaga tccgcgtcgc caccgtgttt cgcaacgccc cggagccatt
     9841 cttacgaatg attgtggttc acgaactggc gcacctgaaa gagaaagatc ataacaaagc
     9901 gttttatcag ctctgctgcc atatggagcc gcagtaccat caactggaat ttgatacgcg
     9961 cctgtggctg acgcatcagg cgctgtcggc acaataaatt ctgaaaatgc cccttccccc
    10021 gtatcttttt aacggcgtgg gcataaaatc gacgcgttca catttcgctc attgcctgcc
    10081 gccacctcaa ggatgacgat ctgtagaggg tattttttat ccaccgccaa cggaaccgcg
    10141 caacaaccat gctctcacaa tgtgcccgtt ttatccgccg cctctgtttt acacgccggg
    10201 cgttaacagt ggcgtgtttt ctgcttgtcg cagcaggcgt cgcgcttttc tattccaact
    10261 ggcttatcgt caacgcctca cagcatctga catggaatga cattcagacc gttcccgccc
    10321 gcaatgtcgg gctggtatta ggcgccaaac ccggcaatcg gtattttacc cggcggatta
    10381 atactgccgc cgcgttgtac cacgccggta aagtgaagtg gctgttagtc agcggcgata
    10441 acggcaaaaa agagtacgat gaaccttcgg cgatgcagca ggcgctgata gcgaaaggtg
    10501 tgccggaagc ggccattttt tgtgattatg ccggattctc cacgctggac tccgtggttc
    10561 gcgcccggaa agtgtttggc gaaagccgca ttacgattat ctcgcaagca tttcataatc
    10621 aacgggcgat ctggctggcg caacaatatg gcattgacgc tatcggcgtt aacgcgccgg
    10681 atctgaataa aaggcacgga acctacacac gacttcggga aaagctggcg cgggttagcg
    10741 cagtgctgga tgccaaaatt ttgcatcgtc agcctaaata tctgggcgct ggcgtcacta
    10801 ttggggctga tagcgcacac gggtgccctt ctcgccagta aaatgccaga gtgcgtcgca
    10861 gcgcactggc aagggcggaa aggcgtgcta cattgacgaa aatccctttc tggagtccgc
    10921 tgacgtttat gatacgtttc gctgtaattg ggactaactg gatcacgcgc cagtttgtcg
    10981 acgccgccca tgaaaccggc aaattcaggc tcgccgccgt ttactcccgt agacttgaac
    11041 aggcgcagtc tttcgcaaat gattatcccg tcgagcatct gtttacctcg ctggaagcga
    11101 tggcgcaaag cgacgcgatt gaggcggttt atatcgccag cccgaattcc ctgcatttct
    11161 cccagacgca gcgctttttg cagcataaaa aacatgtcat gtgcgaaaag ccgctggctt
    11221 ctaacctggc ggaggttgat gccgctatcg cctgcgcgcg cgataatcag cgggtactgt
    11281 ttgaagcctt taaaaccgcc tgcctgccca atttcctgct gctgcgggaa tcgttgccga
    11341 aaatcggcag aatgcataaa gcattactaa attactgcca gtactcttca cgttatcagc
    11401 gctatctgaa cggtgaaaat ccgaatacgt ttaatccggc cttctccaat ggttcgatta
    11461 tggatatcgg gtattactgt ctggcgtcgg cgatcgcgct atggggcgag ccgcgcagcg
    11521 ttcaggcgtc ggcgaattta ttggaaagcg gagtagatgc acacggcgtc gtggttatgg
    11581 attacggcga ttttagcgtc acgctacagc attccaaagt cagcgactcg gtactggcca
    11641 gtgaaattca gggcgagagg ggatcgctgg tcattgaaaa gctgtcggaa tgccagaaag
    11701 tgtgttttgc gccgcgcggc gcgctgatgc aggatctgac ccagcctcag catattaata
    11761 ccatgctgta tgaagccggg gcgtttgccc agcttattga aaaccacgcc gtggaacatc
    11821 cggggttgtc gctaagtcgc gccacggcaa aatggctgac agaaatacgc cgtcaaaccg
    11881 gggtcatctt cccggcggac gatctgactc atccccctac tgcgtaaaat tatgtaaatc
    11941 gtatgttaca ggtcattgac tctacgcgtg gcctgtcata ctttgttacg cgcaaagggg
    12001 agtaacttca ttgccggtcg atcgtcatta cgatgtgtgc aaaaccacat ccggtcaccg
    12061 ggcagccata aaggaatgcg tcagcgtatt cctttattgt tgtaagtgag accttgccga
    12121 atggcaaggt ctatgcataa aagcagcggc taatgccatt cggcattagc cgtttttttg
    12181 catggggaga aataatgaat actgttggta cgccattatt atggggtgga ttcgcggttg
    12241 ttgtggtgat aatgctatcc atcgacttgt tgttgcaggg acgccgtggc gcacatgcga
    12301 tgtcgatgaa acaagcggca ggatggtcaa tcctgtgggt aacgctctcg ctactgttta
    12361 acgccgcttt ctggtggtat ctggctgaaa cgcaagggcg cgaagttgct gacccgcagg
    12421 cattagcgtt ccttaccggc tatctgattg aaaagtcgct ggccgtagat aacgtctttg
    12481 tctggctgat gctgtttagc tatttctccg tccctccggc tctgcaacgc cgggtgctgg
    12541 tgtatggggt tcttggcgcg atcgtgttgc gtactatcat gattttcgcc ggtacctggc
    12601 ttatcactca gttcgaatgg ctgctgtatg tgttcggcgc cttcttgctg tttaccggcg
    12661 taaaaatggc gctggcgaag gaagacgaat ccggcattgg cgaaaaaccg atggtgcgtt
    12721 ggctgcgcgg gcatctgcgc atgactgata cgatcgagaa cgagcacttt ttcgtacgta
    12781 aaaacggcct gctatatgcc acgccgctgc tgctggtgct gattatggtt gagttcagcg
    12841 atgtgatctt cgccgttgac agtattccgg cgatctttgc ggtcaccacc gacccgttca
    12901 tcgtactgac ctctaacctg tttgccatct taggactgcg cgcgatgtac ttcctgctgt
    12961 ccggcgtggc ggaacgcttc tcgatgctga aatatggtct ggcggtcatt ctggtcttta
    13021 tcggcattaa gatgctgatc gtcgacttct accatattcc tatcgcgatt tcgctgggcg
    13081 tagtgtttgg cattctgacc attacgctgg tgattaacac ctgggttaac catcagcgcg
    13141 ataagaaact acgagcgcaa taatctttta tcggggtaaa cctgccccat caaaaacgcc
    13201 cggcagcgta cacctgccgg gcgtttttgt ttaacatgtc acaatactgt taatataaag
    13261 ttataaaaca tgatcacagc aaaaaatcca ggatatttcg cttcccgaac cttcaacttt
    13321 ccttatactc aaccaggcaa acactttgtt acatcctgaa agatgcgccg taagagcgtg
    13381 caggggatga ccagcaacac aatacaagga atatgaaatg gctacgcaac gagcatcagg
    13441 gctactgcag cgtttagcgc aaggcagtct ggttaaacaa attttagtgg gtctggtact
    13501 ggggatttta ctggcatgga tttctaagcc tgtggcagaa gcggttggct tgcttggcac
    13561 cctgttcgtc ggcgccttaa aagcggtcgc ccccgttctg gtgctgatgc tggtaatggc
    13621 ctcgatcgcc aaccaccagc acggccaaaa aaccaatatt cgccctattc tctttcttta
    13681 cctgctaggc accttttcag ccgcgctggc ggccgttgtg ttcagcttcg ccttcccttc
    13741 aacgctgcat ctgtccagta gcgcccagga tatcgtgccg ccgtccggca ttgtagaagt
    13801 cctgcgcggt ctgctgatga gcatggtgtc gaaccccatc gacgcactgc tgaacgctaa
    13861 ctatatcggg attctggtgt gggccgtcgg tctgggattt gccctgcgtc atggcaatga
    13921 aaccaccaaa aacctcgtga acgatatgtc taacgccgtg acctttatgg tgaaactggt
    13981 gatccgtttc gcgccagtcg gtatttttgg tctggtttca tcaacgcttg caaccaccgg
    14041 cttctccacc ctgtggggct atgcgcacct gctggtcgtc ttgattggct gtatgctgct
    14101 ggtcgcgctg gtggtcaacc cgctgttggt attctggaaa attcgtcgca acccttatcc
    14161 gctggtgttc gcctgcctgc gtgaaagcgg tgtttatgcc ttctttaccc gcagttctgc
    14221 cgccaatatt ccagtgaata tggcgctgtg cgaaaaactg aatctggaca gggatactta
    14281 ctccgtttcc attccgctgg gtgccactat caatatggcc ggcgcggcaa ttaccattac
    14341 ggttctgacg ttggcggcag ttcatacgtt aggcgtcccg gtggatctgc ctacagcgct
    14401 gctgctgagc gtggtggcct cgctgtgtgc ttgcggcgcc tccggcgtgg caggcggttc
    14461 attgctgctg atcccgctgg cgtgcaacat gtttggcatc ccgaacgata tcgcgatgca
    14521 ggtagtagcg gtcggcttta ttatcggagt attgcaggat tcgtgtgaaa cggcgctgaa
    14581 ctcatctacc gatgttctgt tcactgcggc agcctgccag gcagaggacg aacgtctggc
    14641 gaataacgcc ttgcgtagct aagtgattat caatgccgga tggcgcgtgc catccggcgt
    14701 gacgataaat cagaatctcc caatccatag gctgtgacgg aaagcgaatt gatgttcacg
    14761 cgcgacatcc tcgcgtaacg ttatatgtag atggcgtctg ccgcagcgct cggtcagcgt
    14821 aaagtataaa gtgtcagcct gtgtaaatcc tctcgccacc ctcctttgcg ataagcaaaa
    14881 tcaaagctca acgacgcgta atttctataa cggacttcgt tgacctttgt tacaattaga
    14941 tgcattttga atttttgtgt gttagtgctt gcttacttca caacttaaca aggaatagtt
    15001 caggccgcga atttgccgtt tccgcaacgc tgataaaaac tccaactctg ttgcggcagt
    15061 gcaaacctca gatcaccggc gtgacgttaa ccgattctcc aggaatactg aatggaacta
    15121 ctgactcaat tgctgaatgc cctgtgggct caggactttg aaacactggc caatccttcc
    15181 atgattggca tgttatattt tgtgttattt atgattttgt ttctggaaaa tgggctgctc
    15241 cctgccgcct ttttgcctgg cgacagcctg ttgatactgg tcggcgtgct gatcgccaaa
    15301 ggcgcgatgg gttttccaca aaccattttg ctgcttaccg tcgcggccag cctgggttgc
    15361 tgggtcagct atatacaggg ccgctggctg gggaataccc gcaccgtgca gaattggctc
    15421 tctcatctcc ccgcacatta tcatcaacgc gcccatcacc ttttccataa acacggcctg
    15481 tcggcattat tgataggccg ttttatcgcg tttgtcagaa cgctgctacc caccattgcc
    15541 ggcatatccg gcctgaataa cgcgcgcttt cagtttttca actggatgag tggcttgttg
    15601 tgggtgctta tcctgacgtc gctgggctat ctgctgggca aaacgcccgt ctttatgaag
    15661 tatgaagatc agctaatgtc atgcctgatg ctgctgcccg tggtgctgct cttttttggc
    15721 ctggcgggtt cactggtcat gctgtggaaa aagaagtatg ggagccgggg ataacttatg
    15781 cttaaaccac gcataactgc ccgacaactc atttggatca gcgcttttct gctgatgctg
    15841 accatactca tgatgacgtg gtcaacgctg cgtcagcaag agtcgacgct ggccattcgc
    15901 gcggttaatc agggcgccag tatgccagac ggcttctcag ttctgcatca tctggatgcg
    15961 aacggcattc attttaaaag cattacgcct aaaaatgaca tgttgctcat taccttcgat
    16021 tcccctgcgc aaagcgccgc agcaaaaaca gtgcttgatc aaacgttacc acacggttat
    16081 gtcgtcgctc agcaggacga tgacaacgaa acggtacagt ggttgtcccg cttacgggaa
    16141 agctcacacc gctttggcta atctccagga atccgaatca tatcactcac tttggtgatt
    16201 tcattgttta atgactatga ttaataaagc ggtgcttaac ccaccgcgtt attatcggga
    16261 tcaccgcccc ggacaacggg tccgaacata agggaaagtt caggaatgaa ataccgcatc
    16321 gctttggcta tcacgctttt tacgcttagc gccggcagct acgctaattc gctttgtcag
    16381 gaaaaagagc aggatataca aaaggaaatt agctacgctg aaaagcacaa caatcagcgc
    16441 cgtattgagg gtctgaacaa ggcgctcagc gaagtacgcg ccaattgtac tgacagcaag
    16501 ctgcgcgccg agcatcagaa aaagatcgct gagcaaaaag aagaggtagc cgaacgccaa
    16561 cgtgatttag ccgaggcaaa agcaaaaggc gatgcggata aaatagacaa acgtgaacgt
    16621 aagctggccg aggctcagga tgagctaaaa aaacttgagg ccagagacta ctaaattaac
    16681 gccgaatgta aatactcact cacctggaga aaactatgtc gaaagataac actacggaac
    16741 atctgcgcgc tgagttgaaa tccctgaccg atacgctcga agaagtgctg agctcttcgg
    16801 gcgaaaagtc gaaagaagag ttgagtaaga ttcgtagcaa agccgagcgc gcgctgaaag
    16861 agagccgtta ccgcctgggc gaaacgggtg atgtgattgc caaacagact cgcgtcgccg
    16921 ccgcccgtgc cgatgattat gtgcgcgaaa acccctggac aggcgtaggc attggcgccg
    16981 ctgtcggtct ggtgttgggc gtactgctga cgcgtcgtta attatggcgg actctcgaca
    17041 ggcacaagga ccaggcaaaa gcgtactggg tatcgggcag cggattgtca ccattatcgt
    17101 tgagatggtg gaaacccggc tgcgactggc ggtagtagaa ctggaagaag agaaagcgaa
    17161 cctctttcag cttttgctga tggtaggtct taccatgctc ttcgcggcgt ttggcttaat
    17221 gagcctgatg gttctggtca tctgggctat cgatcctcag taccgtttga acgcgatgat
    17281 cgctaccaca gttgtactgt tagtgcttgc gctaatcggc ggcatctgga ctttgcgcaa
    17341 agcgcgtcag tccacgctat tgcgccatac gcggcacgaa ctggctaacg atcggcaaat
    17401 tctggaggac gatcagtcgt gagcagcaaa ggcgaacgcg aaaaacgtaa agcgctgctt
    17461 ctcagtcaga tccagcagca acggctggat ctgtccgcca gccgtcgcga ctggctggag
    17521 accaccggcg cgtacgatcg cggctggaat acggtgttaa gcctgcgctc ctgggcgctg
    17581 gtcggtagca gcgtaatggc catctggacc atccgtcatc ctaatatgtt ggtacgctgg
    17641 gcgaaacgcg gcctgggtat ctggagcgcc tggcgcctgg taaaaactac cctccgtcaa
    17701 caacagctcc gcggttaata tcttttcttt tatagcatcg cgccatcagg ttatcacccg
    17761 attacacctg gtggcgcgat acttttatgc atatcgtctc tttatcaatc actcaaattt
    17821 tttgaaaaaa tttggcaatt ttccttgcta acaattcctg tacgccacgt ttatgattct
    17881 ctccagcgat aacaatgacg cgctaaaccg cgccattgct catgaaaata gcagcagccg
    17941 ccgaatcggc ctcctggaga ataaaatgaa aaaattagaa gatattggtg tactgatagc
    18001 gcgtatttta atgccagttc tgtttattac cgcaggatgg ggaaaaatta gcggctatgc
    18061 gggcacacag cagtatatgg aagcgatggg cgtaccagga ttcctgctgc cgctcaccat
    18121 actgcttgag ttcggcggcg gtctggcgat tctgctgggg ttcctcaccc gcaccactgc
    18181 gcttttcacc gctggtttta cgttgctgac ggcattgatc ttccatagca attttgcaga
    18241 aggtgtaaac tcgctgatgt ttatgaaaaa cctgaccatt gccggaggat tcttattact
    18301 ggcgttaacc gggcctggcg cgttcagcct tgaccgtctg ctgaataaaa agtggtaagc
    18361 aatctatact caattaaaaa agcgagggaa tagcgcctcg cttttgttat ctgaaggaga
    18421 gagacatggg acaactgatc gatggcgtct ggcacgatac ctggtatgac accaaatctt
    18481 ccggggggaa atttcagcgt tcagcgtcgg ctttccgcaa ctggcttacc gctgacggcg
    18541 cgcccggacc ttccggcgaa ggcggattcg ccgcagaaaa agatcgttac catctgtacg
    18601 tttcccttgc ctgcccctgg gcgcatcgca cgctcatttt ccgtaaactg aaaggtctgg
    18661 agccgtttat tccggtttct gtcgtgaatc cattgatgct ggaaaacggc tggacgtttg
    18721 atgatacttt tccggcggcc accggcgata ccctctatca gcatgaattt ctctaccagt
    18781 tgtatctgca cgccgatcca cactacagcg gccgcgtcac cgtgccggtc ttatgggata
    18841 aaaaaaatca tactatcgtc agcaacgagt ccgccgaaat cattcgtatg tttaactccg
    18901 ctttcgatgg gctgggcgct aaagccgggg attactatcc ccccgcgctg caaagcaaaa
    18961 ttgacgagtt aaacggctgg atttatgaca acgttaataa cggcgtttat aaagcaggct
    19021 tcgccactag ccagcaagcg tatgatgaag cggtagaaaa ggtgtttact gcgctggcgc
    19081 gcctggaaca gattctcgga cagcaccgct atctgacggg caaccagttg accgaggcgg
    19141 atatccgctt atggacgacc ctggtacgct ttgatccggt ttacgtgact catttcaaat
    19201 gcgacaaata ccgaatcagc gactacctga atctgtacgg tttcctgcgc gatatctatc
    19261 aaataccggg cattgctgaa accgtcaata tggaccatat tcgtcaccac tatttccgta
    19321 gccataaaac gattaacccc acgggtatca tttctgtcgg accgtggcag gatctgctcg
    19381 aacctcacgg gcacgacgtg cgctttggct aatttcaggc gtcctccggg acgccttatt
    19441 aataaatgcc acaaatattt accagcattt cattcgcagc tattcttagt ttgattactt
    19501 taaaaacaag tgattgaacc attattgagg cgaaaatgga ttggtattta aaggttttaa
    19561 aaaattatct gggatttggc ggccgcgcgc gacgcaaaga gtactggatg tttattctgg
    19621 tcaatatcat ctttaccttt gtgttgggcc tgctggacgc catgcttggc tggcaacgcg
    19681 ccgggggtga aggcgttctg accaccattt acggcgttct gatcttttta ccgtggtggg
    19741 ccgtgcagtt ccgtcgtctg catgacactg accgctccgc atggtggcta ctgttgctac
    19801 ttatccccat tatcggctgg cttatcatca tcgcgttcaa ctgccagaat ggtacaccgg
    19861 gcgacaaccg cttcggcccc gatccgaaac gtttttcctg agggcggcgc ggcgccgctt
    19921 ttaaagcgcc gcgcgctatt tattttccgg cgaatagctt aggtatttcc cgcaggcacc
    19981 aggcttttgc ctcccccata ctgtcgcgcc gccaggccat aataatatcg atttcgctgg
    20041 tcgattccgg gctgactacg cgtagccgcc cttcggcaat atcctgttcc accatcgaat
    20101 atggcatcgt cgcgacgcca agcccggcca gcagcgcctg acgtttatct tcaatcgtgc
    20161 ttaccgtcag acgtggctgc ttatccagca gttgcaccgt taataccggc cgctcgcgcg
    20221 cggtatccgc taccgctacg ccgcggtatt taacccgcgt cacttccgaa agcggctccg
    20281 gctcctgatg aatagagtgg tcaggcgcgg cgacatacac attcattaac gtatacaact
    20341 tacgggagtt aatttccgac gacgatcgaa aatgcatatc cggggcgata acgatatccg
    20401 cccgtccctg ctcaagccgc tcccatgcgc cagccagtac ttcggtaatc aatgaaagct
    20461 gcgtattggc tttagcggcc agccggtcga tcagcggaaa aaaagcaggc gtcggtacca
    20521 gagcttcagt gaccagcgtc agatgcgttt cccaaccgcg ggccaacgct tcagcatccg
    20581 tcgttaactt gtctgccgct tccagcaata cccgcccgcg ttccagcagc atacgtccga
    20641 cgttggtgaa ttttgtacga tggccggagc gatcgaacag tacaacgtcc aactcttctt
    20701 ccagcttctg catggtgtaa ctcagcgcgg agggcacccg ccccaactca tcagccgctg
    20761 cggcaaaact gccccggcgg tcaatggcgt ccatcacacg caatgcttca agcgtcagcg
    20821 ctctctcttt agccataacg ttctcattca ggaaatttga acataccggg cagaatatct
    20881 ggctaacaat gcagcgtcca gccccttaac ataaaaggaa gtaaagagag gttaataacg
    20941 atgattacga cccgaaccgc caaacaatgt ggacaggcag actacggatg gctacaggcc
    21001 cgctatacct tctcctttgg acactacttc gaccctacac tgctgggcta cgcgtcgttg
    21061 cgcgtactga accaggaagt gctggcgccg ggcgcctctt ttcagcctcg aacttatcca
    21121 aaggtggata ttttaaacct gattctggac ggcgaagcgg aataccgcga cagcgacggc
    21181 aaccatgtac aggctaaagc gggcgaagcg ttgctgctcg ccgcgcagcc gggcattagc
    21241 tacagcgaac ataatctcag caaagttaag ccgttaaccc gaatgcaact gtggcttgac
    21301 gcctgtcctg aacgggaaaa cgcgctggta caaaaaatcc cactctcgac ggcgcaacaa
    21361 cagcttcttg cctcgcccga cggtgagcaa aacagcttac aactgcgcca acaggtctgg
    21421 gtacatcata ttacgctgga gaaaggcgaa tcgcttaact tccagcttca cgggccgcgc
    21481 gcctatttgc agtcgattca cggtacgttc cacgcgatga cgcacaacga agaacgcgag
    21541 gcgttaacct gcggagatgg cgcatttatt cgtgatgaac ctaacattac gctggttgcc
    21601 gatacgccgc tgcgcgcatt actggtagat ttaccggtgt agccagccag aaaaggagtc
    21661 gcaagatgag caaaaaatcg gcgaagaaac gtcagcccgt ggtaaaacct gccgtacagg
    21721 aggcgatgag cgccgctgtg ccgctgggct atgaagagat gctaaccgaa ctggaagcca
    21781 tcgtggcgga cgccgaagcc cggctggcag aagaagaggc cgcagcctga aatcatgccg
    21841 gatggcggcg caagcgcccg atccggctga taacgggtag acccgataag cgcagcgcca
    21901 tcgggcaaca cgctgccccg acgtcatgcc ggggcgttat tattaatgcg ctttactggc
    21961 cataatctcg atgatctgct tgtctgtctg ctgcattgag cgacacgcca gcgaacacaa
    22021 attcgaaata gattgttcga cattgtgcgc cacaatccct tcgtttccgg tcaccgccgt
    22081 atcatccaac gccatcagta cggctttcca cgccgccgac gcgctggtag agactttcat
    22141 cgcgcagcta ttcgacgcgc catcgcaaat catcccgctg acatcaccaa tcatactgct
    22201 gatagccatt gcgatagtgt cgtaacgacc atctatcagc cacgccatac ccgctgccgc
    22261 gcccattgcc gccgtagttg ccgcgcacag cgccgacaaa cgcggaagct gatggtgaat
    22321 atagatagcg ctcaaatgcg ataacattag cgcgcgcgcc aggcactcgt catcggcgcc
    22381 gacatgttca gcaaccacca tgactggcac cgtggcggta atcccctggt tgccggagcc
    22441 ggagttgctc atcgcgggca acgtggcacc gcccattctg gcgtctgacg ccgcgctggt
    22501 acggatcaaa atcgccgtgg agagatcttt cgccagcaga ccgcgatcgc actgtttggc
    22561 cagcgtcgaa ccaatatgca gcccccagga accacgcaag ccctcctgcg acaacgcgcc
    22621 gtttagcctg gccgcatcga gaataaagcg gatagcgtca aagggcaccg cattcacaaa
    22681 cgccaggatc tcttccagcg aggtatgaga cagcactccc agtggcgagg ttttttcttc
    22741 ttcctgcgca ttatcggctt gggtaaatac cacgcccttg tcggtttcta tccgcacaat
    22801 atttgtatga tcgccgacga tcgtgacaca tgcccagcta tcgccgctat acactttcgc
    22861 ccgtgaaaac aggatatcgt tacatggctc ctgcaacatc actgcaacat gtccggcggc
    22921 cagcatcgct tttgcatcgg caacggcttt agcggaagcg tcttttaaca cctccaaccc
    22981 ggctttcgca tcaccgccca acgcgccaag cgccgcggcg atcggtagcc ctaccattcc
    23041 cgttcctgga acggtaacgc ccataccatt tttcatcaga ttaggcgaaa cccacgcgtc
    23101 aatgcgttca actgtgccgt caagttcagc cgccgccgcc gctgctgcca gcgccagtga
    23161 aattggctca gtacacccca gcgccggttt tacttcttcc tgtacggcca ggataaaact
    23221 ttgccacaat ggatttattt tagattcaaa cataacaaca accttaatct caggtatatc
    23281 aagagaatgc caggaacgga gaaacgcata gcagcagacc ggtaataata atcaggtaca
    23341 acgaagcgcc tttatatttg tgcaatgcgg gaaccttgta gaccaaccat gccggaatta
    23401 aacagcccac cataccgaag atagggctac aaatagaggt gaagctcagt accggcgcgt
    23461 tgagcacaat ggcgctccag gccagcaaaa tagcgaaaat cataatgccg cgctgtacca
    23521 gattttcctt aatcttctcg gcgggcattt tgcggcgcag gatattcatc acaatgcctt
    23581 gcgtcgcttc gcggaatcct aaataaacgc caaagaaggc ggtcatgacg gcaaagatgt
    23641 tcagaattac gctaaccact ttgacccagc tagcgccatc gccgctaata aattgcgcgg
    23701 cgatcgccag ggcggaaata ttctgctcgt aggctttcac cgcttcgtca tgccccatcg
    23761 ccagggtgaa ggaaaccgca tagaaaaaga cggtaacgaa caggatgcca aacgcgatat
    23821 tcatggcgcg cagcgcttat ggcgtgcgac ctcaatagat ttttcgcgtg aacggtaaga
    23881 gatcaccatt gggcttaacg tctggataaa taaaatcgag gtcagcgtaa atggcagggt
    23941 aataatggcg tttttaatca gcagggccat cggcggcagc gcgccaatgt tatacagatg
    24001 ccacataccc accatagaga cgcccagcgc cgccactacc agtagcttgg tcagcaccat
    24061 gccggtggaa attttgaaca gtaatttttc accgcgtgag gaaatcgcca ccaggatgca
    24121 gatcagcacc agaccataaa atggactatc ggaaagtaat ccttccgtta cgccgaaagt
    24181 atgcagataa gaggcgctgt cgttagtaat cgccgtagaa tagacgaaca tccagatgac
    24241 gagcatcaca aagtacagcg cgcctaataa aataccccag tttttgccca gatagccgct
    24301 gatcacgctg gggtagtctt tacattccgg ggattccgcc agcgtattaa taaacagccg
    24361 ctggaacagg tacatggccg gataaccaat aatagaagag agtaaaaaga cccaaagtcc
    24421 catcaggcca acctagacag gaagaaaaac gatccctgcg ccgatcgcca tcccgatact
    24481 cataatgacc cagccggtgt cggtactatc aaatttgatg gcttcacgcc attcgctttc
    24541 tgtcatccct gcccgacgcg ccggggctga tgcgtcgagg attacgctgg tattactagc
    24601 cgattccata aaattctcgc tcaatgtgta ggtagaggtt tttttatttt tcgtgccgca
    24661 gcaaggcgat atgcagaacg tgaggtgcag gtactttctt gtaataagaa aatcatacgc
    24721 gcacgataag agaaaaactt accaataaaa cgcctgcatt tcttgtgggt taagaattat
    24781 tttctattta ctatttattt aatattgtta ttttctctat ttgacgcgta tcacaacaaa
    24841 aaagggcgca ctttggtgcg cccttttctc agcttctgtc ttctgcgtta tcccatagcc
    24901 tgctcactct gcgcctgtcg ggcctatcca caaacgactt taatcgccag accgccgcgc
    24961 gacgtctcgc gatatttgtc gttcatgtct ttacccgttt cgtacatggt ttcgatcact
    25021 ttatcgagcg aaacccgcgg ctcagaggta cggcgtagcg ccattcgcgc cgcatttacc
    25081 gctttaacgg cgttaatcgc attacgttca atacaaggga tttgcacctg acccgccacc
    25141 gggtcacagg tgaggccaag gttatgctcc atcgcaattt ccgccgcaat acagacctgc
    25201 gccgggctgc cgcccagcag ttctgtcagc cccgccgccg ccatcgaaca cgcgacgcca
    25261 acctcgccct gacaccccac ttccgcgccg gatatcgagg cgttcatctt gtacagcatg
    25321 ccaattgccc ccgccgacag cagataacgg gcgatagagt tggcattgac cggacgacgg
    25381 aatttgtcgt aataggccag caccgcggga ataatgccgc acgcgccgtt ggtcagcgcg
    25441 gtgaccactc gcccgcccgc cgcgttctct tcgctcacgg ccagggcgaa catgttaatc
    25501 cagtcgatga cgttcatcgg atcgcgggag agattatcgc tggagaccag cagacgccgt
    25561 aacgctaccg cgcggcgtgg gacgttcagc ggccccggca gcacgccctc agtattcatg
    25621 ccacgttcaa ttccggtcgc catcacctgc caaatgcggg caaagccagc gtcaatctgc
    25681 tctttgctcc gcaacgccag ttcattttgc atcatcaggc cggaaaccga gagcccctgc
    25741 ctttcacaca gcgtcagcag ttcgctggcg gaatgaaaat catacggcac cgatttttct
    25801 acgtcgtgcg actgaccaaa acgttcctct tcgacaataa agccgccgcc aatagagtaa
    25861 tacgttttgt gtaaaagcgg cgtttgcccg tgccaggcgg taattcgcat accgttttca
    25921 tggcgcgcca gggtttcagc gtgaaagaga atactgtcgg cgacgggaaa atccaccaca
    25981 tgcgcgccac ccgccaccga taaacggctg ctgcgggcaa cctcctggat aaacgccgga
    26041 atgctatcaa tattgacatc ctgcggcgta ttgcccgcaa gacccataat gatggcggta
    26101 tcggtcgcgt ggcctttgcc cgtcagcgat agcgatccgt aaagatcaac cgtgatgcgc
    26161 gtcgttcgcg gcaggtcgcc gctgtcgatc agccgatcga taaaacattt tcctgcattc
    26221 attggcccta cggtatggga gcttgaaggt ccaatgccaa tcttaaaaat atcaaatgcg
    26281 ctaatcatat ctccccctaa gattaccgtt cagtgaagat ccgtcgcggg gcgatccaca
    26341 cgatcgcccc gttcacgtta catcgcctga gtaaaggtgc gcgaaataac gtcctgttgc
    26401 tgctcacgag tcagcgcatt gaagcgcacg gcatagccgg aaacgcggat cgtcaggttc
    26461 gggtagtttt ccggatgttc aatcgcatcc agcaacattt cacggttcat gacattgacg
    26521 ttcagatgct gcccgccttc tacctgtgct tcatgatgga aatagccgtc cagcaggccg
    26581 acaagattgg ttttccgcac cgcatcttct ttcccgagcg ccgcaggcac aatcgagaag
    26641 gtgtacgaaa taccgtcttt ggcgtaggta aacggcagtt tcgccaccga cgtcagcgag
    26701 gccaccgccc ctttgcggtc acgaccgtgc atcgggttcg cccccggcgc gaacggcgtt
    26761 ccggcgcggc gtccatccgg cgtattgccg gtcttctgcc cgtacacgac gttcgaggtg
    26821 atggtcaaaa tggactgcgt cggcaccgca ttgcgatacg tcggcaacac gctaattttt
    26881 tgcataaagc gtttcaccag gtcgcaggcg atgctgtcca cgcgctcatc gttgttgccg
    26941 tactgcggat actcgccttc aatagcaaag tcgatggcaa ggccattttc gtcgcgaatc
    27001 ggcttcacct gagcgtacct gatggcggat agggaatccg ccgccaccga cagtccggcg
    27061 atgccgcacg ccatcgtccg atacacatca cggtcgtgca gcgccatcag cgaagcttca
    27121 tagctgtact tatcgtgcat atagtgaatg atgttcagcg cgctaatgta ctgcaccgcc
    27181 agccagtcca taaaatggtc gaggctctcc attactgcgt cataatccag cacctcatcc
    27241 gttaacggcg cggttttcgg cccaacctgg attttcagtt tctcgtcaac gccgccattg
    27301 atagcgtaca gcaacgtttt ggcaaggttg gcgcgcgcgc cgaagaactg catctgctta
    27361 ccgatgacca tcgggctgac gcaacaagcg atggcgtaat cgtcgctgtt aaagtcggta
    27421 cgcattaaat cgtcgttttc atactgcaaa gatgaggtca cgatggagac ctgcgcagca
    27481 tatttcttga atgccaccgg caacgcttct gaccacagta tggtcaggtt cggctccggc
    27541 gctggcccca tcgtgtgcag ggtatgcaga taacggaaag agttcttcgt caccagcgtg
    27601 cggccatcaa gccccatccc gccaataact tcggtggccc agatcggatc gccggaaaag
    27661 agcgaatcaa attccggcgt gcgcaggaag cgcaccatgc ggatcttcat gatgaaatgg
    27721 tcgatcagct cctgcgcctg ctgctctgtc agaagacccg cgttgaaatc gcgctcaatg
    27781 tagatatcaa ggaacgaggc ggttcttccc agcgacattg caccgccatt ttgcgatttt
    27841 accgccgcca gataagcgaa gtagagccac tgtaccgctt cctgcgcgtt ccgcgccggg
    27901 cgggagatat catagccgta tttcgccgcc atctcctgca tttgcagcag cgcgcgacgg
    27961 tgctccgcca actcctcacg caggcgaatc gtcgcctcaa gattctgtcc ccgctccaga
    28021 ttcgactgca ggtcggcgaa ttgcagctcg cgttcgcgca ccagataacg gatgccatac
    28081 agcgcgacgc ggcgataatc gccaataatg cgcccgcgac cataaccatc cggcaaaccg
    28141 gttaatacgc tggatttacg gcagcgcagc atatccggcg agtaaacatc gaatacgccc
    28201 tgattatggg ttttccgcag gtcggtaaag gtatattcaa aatcggcgtc catttcccgg
    28261 ccataagcgt ggaatgaact tttgatcatg ttaacgccgc caaacggatg caaagcgcgt
    28321 ttaagcggct tatccgtttg taaaccgacg attttttcca gctctttttc aatatacccc
    28381 gcatcgtgcg cggtaatcgt cgtcgcgatg ttggtatcga aatccaccgg cgcatgggtc
    28441 gcgttctcga tacgtattcc cgccatcacc ttttcccaca acgctgtggt cgctggcgtc
    28501 gcgtcggcga gaaaagattc atccccctca tagggcgtat agttatgctg aataaaatca
    28561 cagacattaa tttcttcttt ccagtccgta cctttaaaat cacgccatgc ttcggcatac
    28621 agcatatcgc tggtatcgat atttaccttc atgaaaaata atctctctac agaacagccg
    28681 ttaagttatg caaattccac tggtgctttc acgttgccta aatgaatggc atcaagggca
    28741 atcattttct cttcattcgt gggaataaca gcgcaaataa cctgagaagg gttaacggaa
    28801 ataatgcgct cgccgtgaga attcggctgc ttattcattt caacgtctaa cgtaagcccc
    28861 agtacgccca aatgttcaat gaccaactgg cgaattaata ctgaattttc accaataccg
    28921 ccggtaaaaa taatgccatc cagccgatgt aacgatgccg cgtgtccggc aatgtgacgg
    28981 gcgatacggt ggacaaacgt ttttatcgct aaccgggcgc gctcatgtcc ttcgtgccag
    29041 gctttttcca ggactctaag gtcggatgac aacccggaga tgccgagcaa accggactct
    29101 ttattcacca ctcgctccag atcgctcaac gtctgcccgg tttctttggc tatccacgcc
    29161 atcgcgccga aatcaacgtc gccgctgcga gtgcccatca tcagcccctc aagcggcgtc
    29221 atccccattg aggtgtccac gctctgacca ttgcgtaccg cgcagataga cgccccattg
    29281 cccagatgcg cgacaatcag acccgagttt ttttcatcga ggtcaagcag ttcatacgcg
    29341 cgccgcgaaa catagcgatg cgacgtaccg tgaaagccgt agcgacgcac acccaggctg
    29401 gaaaaatatt cccacggcaa tccgtataaa taggcttccg gcgccagcgt ctggtggaaa
    29461 ctggtatcaa ataccgccac ctgacgcacg gccgggaaaa ggcgccgcgc cgcgtcaatg
    29521 ccgcttaaat tagcgtaatt atgcagcggc gctaaaggtg atacccgacg aatattatcg
    29581 ataatctcat cggtaataat gacggactgc gtaaatagct ctccatcgtg cgcgatacgg
    29641 tgaccaatta atgccacgct atccgttaaa tcacgttttt ccagctcaaa ggcaatggct
    29701 tttaacgcgt cctcataatt agagtgcgag aggtttatcg gcttatcgcc attaatagat
    29761 aaaaaggcgt tttcagtatt cattccatct gctattcccg ccattaaaac atcacaggta
    29821 gcgacatcca gtacagagaa tttgatagaa gatgatccgc aattaatgac cagaacgacc
    29881 ggaaattcat tcatgtagtg cctccgtcga tgtcagcctg cgtccacgcc ctggggcgga
    29941 acgcaggcta aacgtgagga ttagaacaat ttgtagacaa tattcaggat ggtcagcaga
    30001 ccaatcaggg tgacgaacac gttatccaga cgaccacggt acttcgccag cgacggcgct
    30061 ttacgaatgg cgtacatcgg cagcaggcat aacagtgagg cgataatcgg cgcgcccatc
    30121 gcttcaatca ggtccagaat gttcgggttt gcgtaagcta cgacccaggt agatcccata
    30181 atgaagatca tgctgatggt attaagcttg cccatagaga ctttggtttt atcgccttta
    30241 taaccgaatt tcagcaccag gccgttcagc ccttccagcg tccccaggta gtggccgaag
    30301 aaagatttga aaatagcaac cagcgcgatg atagacgcgc catactccag caccgttgca
    30361 aaagtggatt ttgtccccga caaagaggcg aaatggttgg ccaggtagga aagtaccgga
    30421 atgttctgcg ctttcgcatc cgccatgttc tgcggggaga gcgtaaacag acagctaaag
    30481 gcgaagaaca tcaccacggc gaccatcagc atatggcgcg cgagatgatc tgtgaacatt
    30541 tacgctcggt aaattcgcgg ccaaactctt tctcatactc ttcacgctta gacaccacga
    30601 aggaagagac gatgggcgaa aagttaaagg agaacaccat aatagagatg cccagccaca
    30661 ccgtaaccag tatgccatcg tgcccggtca gcgcgatatt actgagatca acctgatcga
    30721 taaccgccga gttccagtaa ggaatcagcg ataatgagat tagcaccaga ctggcgataa
    30781 acggccatac caggtaactc atcaccttaa ccatcagatc tttaccaaac cagatcacaa
    30841 aggccatcag cagcagcaag aacagcgcca cgaaaccgcg attcaacgct ggtatctgca
    30901 actggttttc ccaaaacgtc atgaacgtgt tagtaatggt gacgccataa atccacagca
    30961 gcggacaaat cgcaaagaag taaaggaacg tgataactac cccgcccgtt ttaccaaagt
    31021 gctcttcgac cgtttccgta atattgccgg acggattaga cccggataaa cacagacgcg
    31081 ccagcgcccg gtgacaatag aacgcaatgg gataagctaa aaccagcatc agcagaatgg
    31141 ggataagccc gccaaacccg gcgcggatag ggaagaacag caccccggcg ccgatggcgg
    31201 taccaaataa acccagcgtc cacgtcgtgt ccgatttacg ccatgacgac tgttttgcct
    31261 ggctggatac aatgctatca gtagtactca tatcctatcc tcacgaaaag attaagcgtc
    31321 aactaaaccc gtaatttgtg atacacgaga aagatcgata ttgccgccag aaataatact
    31381 gaccgttttt ctgttctgaa tatggctatc taatttcccg cttaatagtg cggcgcaggc
    31441 cagtgcgcca gcgccttcag taataacctt attgcgctga attaaagcga tcatgctgtt
    31501 acgaatttca tcttcgctaa ccagaacaat gtcatcgact aattcacgaa caatttcata
    31561 ggttaaatta cccgggcggg agacatcaca accatccgcc agggtgccgg tcgttcggtg
    31621 cgcggttatt tcgccagcgt aataagacgc cgccataccg tgaacatttt cggcctgtac
    31681 gccgataact ttaatggtcg ggttaatcga tttaatcgca atggcaatac ctgcaattaa
    31741 accgccgccg ccaataggca cgatgacatt atcgacatcg tacagatctt ccataatttc
    31801 cagaccaata gtaccctgcc cggcaatgac ttttggatcg tcgtaaggcg gaataaaaat
    31861 gcggccttcg gtttcgacaa tttcactcac cttagcaatg gtgtcattga agttgtcacc
    31921 gtggagcacc acttccgccg aataatcaca ggtggccgcc acttttgact ttggcgcgcc
    31981 cttcggcatc acgactttgc cgtcaatacc cagcattgcg caagaaagag aaacgccctg
    32041 tgcatgatta cctgtggaac aggccacgac gcctttacgt ttttccgcct ccgttaacga
    32101 gctaagtttg ttaaaagcgc cacgaatttt aaatgaaccc gtacgctgca tattttcaaa
    32161 cttgagaaat atttcgcctt tgcaacgttc actaaaatag ttagagcgag gcattcccgt
    32221 tttatatatc ttccccgcca gtcttttttt cgcttcgagg atatcttcaa ttgcaaccgg
    32281 gagatcgtat gtaatgtgca ttataacctc ttaacctggg tattaaaaat aagttaccgt
    32341 tgcccactgt tcaaaagaaa caggtggcgt caatttcgct aaatatgttt attccatatc
    32401 attcaatttc tattaactgc ctgcgtctgc atccattata tgatgaatat tgcttagcca
    32461 attctactaa tactgaagcg gcttttttga tacgataatt tttagaccat accgccgcat
    32521 aacgtgcgac gggtaatgtg tctttgattg gtatcgtgat aaattgatta gagccaaaag
    32581 gcgtggtcat atcgcaggga ataacagtta agaaatcagc attgagaaca agattatata
    32641 ttgtgacaac ggaatctgtt ttaacaatgt tttcgatgct gatgccattt cgttgtagag
    32701 tggtgagtaa ttcgctgtag tagcccatat tcgtttgcgg caacgcccac tgttcgtcct
    32761 ttaacgattc cagtgtgatg gtgccggtgc atgttcggga cttgctggct accaggacaa
    32821 actctgattc aaacagcggc tcgacatgca gatcctgtag ctgcatttca ttactgagcg
    32881 taccgatagc aaagtccagc cgcccgtcgc gcagggccgg caggaatgaa gagagctggg
    32941 cttcgtacat ggatacctgc gcttttggaa atacctcttt gaacttatga atcatatcgg
    33001 acatgaaggt aaagccaatc agcgaaggaa aaccaaacga gacgtcgaca acggtattgc
    33061 acgtcatact gttcatctcg ttgatcatgt ttttcatttc gcgggtgata gattcagacc
    33121 aggaaagcag tacctgtccc gcttcggtca acgtaacgcc ggtatttttg cgtacaatta
    33181 gctcaacgcc aaaataggcc tcaacatcgc taatgatttt actgacggcg ggttgggtta
    33241 accctaacga ttttgcggca gaaccgatag aaccacttct aatgacttcc tgaaagacca
    33301 ccaaatgctg tgttttaggg agaacaagag tattcatatc taccgctctg aaataacatt
    33361 gtgaacggca ggaagtgtag caaattaaat cttaaaggtt atgtgcgacc actcacaaat
    33421 t
//
LOCUS       DAJVKX010000039        32767 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000039 DAJVKX010000000
VERSION     DAJVKX010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 32767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32767
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.039"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(141..1250)
                     /gene="apbC"
                     /locus_tag="OPY25_001872"
     CDS             complement(141..1250)
                     /gene="apbC"
                     /locus_tag="OPY25_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HCS0927499.1"
                     /translation="MNEQSQAKSPDTLRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWNSAFEVLKEQCSADLLRITGAKAIDWKLSYNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALEAEGAKVGVLDADIYGPSIPTMLGAEDQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSMHICSNCGHHEPIFGTGGAQKLAEKYHTQLLGQMPLHISLREDLDRGTPTVVSRP
                     ESEFTAIYRELADRVAAQLYWQGEVIPGEIAFRAV"
     gene            1415..3448
                     /gene="metG"
                     /locus_tag="OPY25_001873"
     CDS             1415..3448
                     /gene="metG"
                     /locus_tag="OPY25_001873"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCS0927500.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSDE
                     NRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSADQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTT
                     SFDEYWKKDSDAELYHFIGKDIVYFHSLFWPAMLEGSHFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLKHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLAAELADPQLYKTFTDAAAVIGEAWESREFGKAIREIMALAD
                     VANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPTLSERVEAFLN
                     SELNWDAIEQPLLSHKVNTFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADFP
                     IQETITFDDFAKIDLRVALIENAEFVDGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRQTVMVANLAPRKMRFGVSEGMVMAAGPGGKDIFLLSPDDGAKPGQQVK"
     gene            3689..4147
                     /locus_tag="OPY25_001874"
     CDS             3689..4147
                     /locus_tag="OPY25_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HCS0927501.1"
                     /translation="MKISGKLLSAALASVLVFSLAGCGDKEESKTFNANLAGTEISIT
                     YTYKGDKIIKQTSESKISYATVGAKTKEDAAKILDPLSAKYKNIAGVEEKLTYEDTYA
                     QENVSVDMEKVDFKALQQISGTMVSGDTSKGISMKQTQTLLEAAGFKEAK"
     gene            4319..4849
                     /locus_tag="OPY25_001875"
     CDS             4319..4849
                     /locus_tag="OPY25_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HCS0927502.1"
                     /translation="MQVLRLMALPLFALSLSVSITGCDQKNDTLQGKQNNMTAFIKKI
                     AASKESEETQRYVGNLNGIEIKLTYYYKGDIVLRQISEHKLLYKTLKANNKEEAQKML
                     SQVGEAYQGMPGLTERIDYYDSYATEYVDIDFTQAKISDLCKLPGSSIDNCSAYYLSM
                     IRSQKLLEESGYHRIN"
     gene            complement(4906..5373)
                     /locus_tag="OPY25_001876"
     CDS             complement(4906..5373)
                     /locus_tag="OPY25_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HCS0927503.1"
                     /translation="MLSNDILRSVRYILKANNTDLARILALGNVDATPEQIAIWLRKE
                     EEEGFQRCPDIVLSSFLNGLIYEKRGKDEAAPALTAERRINNNIVLKKLRIAFSLKTD
                     DILAILTGQLFRVSMPEITAMMRAPDHKNFRECGDQFMRYFLRGLAAREHAAK"
     gene            complement(5420..6139)
                     /gene="yehT"
                     /locus_tag="OPY25_001877"
     CDS             complement(5420..6139)
                     /gene="yehT"
                     /locus_tag="OPY25_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HCS0927504.1"
                     /translation="MIKVLIVDDEPLARENLRILLQGQDDIEIVGECANAVEAIGAVH
                     KLRPDVLFLDIQMPRISGLEIVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IEEKRLEKTLHRLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMDDVAFVSSRM
                     SGVYVTSSEGKEGFTELTLRTLESRTPLLRCHRQFLVNMAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(6136..7821)
                     /locus_tag="OPY25_001878"
     CDS             complement(6136..7821)
                     /locus_tag="OPY25_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCS0927505.1"
                     /translation="MYEFNLVLLLLQQMCVFLVIAWLMSKTRLFIPLMQVTVRLPHKL
                     LCYVTFSIFCIMGTYFGLHIEDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSVLIRRGRPDKVFSPLTAGAITCVAELVQMLIILL
                     IARPFDDALHLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSVTALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISSG
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKALLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEIVTLADEIEHVNAYLQIEKARFQSRLQV
                     QLDVPSTLSRQKLPAFTLQPIVENAIKHGTSQLLDTGNVAIRARREGQHLMLDIEDNA
                     GLYQPSAGSSGLGMSLVDKRLREHFGDDYGISVACEPDCFTRITLRLPLEEDA"
     gene            8044..8775
                     /gene="mlrA"
                     /locus_tag="OPY25_001879"
     CDS             8044..8775
                     /gene="mlrA"
                     /locus_tag="OPY25_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HCS0927506.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKVLLSSDSSEQPNGWREQQEILLHYLQSSNLHSLRL
                     WVKERGQDYPAQTLTTNLFVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKK
                     QGKDALVIGWNIHDTTRLWLEGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGE
                     HQTLAQQQQLLAWRAQGHDIHPLGV"
     gene            8835..8942
                     /locus_tag="OPY25_001880"
     CDS             8835..8942
                     /locus_tag="OPY25_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HCS0927507.1"
                     /translation="MRVAKIGVIALFLLMAIGGIGGVMLAGYSFILRAG"
     gene            complement(8923..9654)
                     /locus_tag="OPY25_001881"
     CDS             complement(8923..9654)
                     /locus_tag="OPY25_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0927508.1"
                     /translation="MKRLCDPLLWLIVLFLLLLFGLPYSQPFFAALFPDLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVVVGVGAGIAVTRESGKEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVMGFGQQPAIIALILYGVLPILQATLAGLGAVPASVMSVASGMGMSRRQQLY
                     QVELPLAAPVILAGIRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIIDRLFERLTRALTRHAK"
     gene            complement(9638..10585)
                     /locus_tag="OPY25_001882"
     CDS             complement(9638..10585)
                     /locus_tag="OPY25_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0927509.1"
                     /translation="MIEFNHVSKTFGDQQAVSDLNLHFSEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGTIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWTVAQNIATVPQL
                     QKWSRARINDRIDELMALLGLESALRDRYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHQLLGRTIVLVTHDIDEALRLADHLVLMDGGHVIQQGS
                     PLSMLTSPENDFVQAFFGRSELGVRLLSLRSVGDYVRRHEQLSGDALVEEMTLRDALS
                     MFVARRCDVLPVANQQGEPCGTLHFRDLLSETSPRETTV"
     gene            complement(10578..11747)
                     /locus_tag="OPY25_001883"
     CDS             complement(10578..11747)
                     /locus_tag="OPY25_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0927510.1"
                     /translation="MSDAAKKITVNRVLLLLVVLALLAVALPFINYAPNRLVSGEGRQ
                     LWEIWPATIWMLTGAGCALFTLCFVPGKRGSVLTLMMAQTLFIVMLWGVGRAATQLAQ
                     EGSPLARTSLGSGLWLGLGLMLLACSDAIRRITVGPLWRWLLHAQIVIVPLALLFSGT
                     FDNLSLLKEYTNRQDVFDAALVQHLMLLAGTVLPALAIGLPLGVWCYFSASRQGPVFT
                     VLNVIQTIPSVALFGLLIAPLAGLVKQFPWLAEFGVAGTGMTPALIALVLYALLPLVR
                     GVVAGLNQVPRDVLESARAMGMSSGQRFRHVQLPLALPVFLRSLRVVMVQTVGMAVAA
                     ALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIALAVVIDALFDLWIAFLKGATDD"
     gene            complement(11751..12668)
                     /locus_tag="OPY25_001884"
     CDS             complement(11751..12668)
                     /locus_tag="OPY25_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCS0927511.1"
                     /translation="MTISKLWVSSLALLATVSLPLQAASPVTVGSKIDTEGALLGNMI
                     LQVLESHGVKTVNKIQLGTTPVVRGAITAGELDIYPEYTGNGAFFFKDENDPAWKNAK
                     QGFEKVKKLDAEQNKLVWLTPAPANNTWTIAIRQDIAEKNKLSSLADLSRYLKEGGTF
                     KLAASAEFIERSDALPAFEKAYDFTLNQNQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPKGVQPIYAPAPVVRESVLQAYPQIADWLQPVFASLDEKTL
                     QQLNARIAVEGLDAKKVAADYLRQKGWVK"
     gene            complement(12850..15147)
                     /gene="bglX"
                     /locus_tag="OPY25_001885"
     CDS             complement(12850..15147)
                     /gene="bglX"
                     /locus_tag="OPY25_001885"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HCS0927512.1"
                     /translation="MKWLCSVGVAVSLAMQPALAENLFGNHPLTPEARDAFVTDLLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRQMQDQVMALSRL
                     KIPLFFAYDVVHGQRTVFPISLGLASSFNLDAVRTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSIMGETMVKAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSSQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     EWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKAGVDMSMADEYYSKYLPGLIKS
                     GKVTMAELDDATRHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESVVLLKNRLETLPLKKSGTIAVVGPLADSQRDVMGSWSAAGVANQSVTVLAGIQNAV
                     GDGAKILYAKGANITNDKDIVDFLNLYEEAVKIDPRSPQAMIDEAVQAAKQADVVVAV
                     VGESQGMAHEASSRTNITIPQSQRDLITALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPISFPRSVGQIPVYYSHLNTGRPYNPEKP
                     NKYTSRYFDEANGPLYPFGYGLSYTTFTVSDVTLSSPTMQRDGKVTASVEVTNTGKRE
                     GETVIQMYLQDVTASMSRPVKQLKGFEKITLKPGERKTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGVDSARVKQGSFELL"
     gene            15414..17144
                     /gene="dld"
                     /locus_tag="OPY25_001886"
     CDS             15414..17144
                     /gene="dld"
                     /locus_tag="OPY25_001886"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HCS0927513.1"
                     /translation="MSSITMTDNKTFLNELARLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLNACVNADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTQ
                     RLDKLHLLDNGQQVLAWPGTTLYALEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARIDEQGKLQLVNHLGIDLGHTPEQILSKLDDERIKDEDVRH
                     DGRHAHDHDYVTRVRDINADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFAAEKNQ
                     QVFYIGTNQPAVLTEIRRHILANFDNLPVAGEYMHRDIYDIAEQYGKDTFLMIDKLGT
                     DKMPFFFTLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVAEAQRWLNEFFKSAEGGFFTCTPEEGSKAFLHRFAAAGAAIRYQAVHAD
                     EVEDILALDIALRRNDTDWFEHLPPEIDSQLVHKLYYGHFMCHVFHQDYIVKKGVDVH
                     ALKAQMLELLQARGAQYPAEHNVGHLYKAPETLTRFYRQNDPTNSMNPGIGKTSKRKF
                     WQENTPDETH"
     gene            complement(17203..18111)
                     /gene="pbpG"
                     /locus_tag="OPY25_001887"
     CDS             complement(17203..18111)
                     /gene="pbpG"
                     /locus_tag="OPY25_001887"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416638.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HCS0927514.1"
                     /translation="MLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSN
                     HPDLVRPIASITKLMTAMVVLDARLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKN
                     MLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVS
                     TARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTK
                     TGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAA
                     LSYKKQKAAQMAAASASAGAQTAQND"
     gene            complement(18316..18903)
                     /locus_tag="OPY25_001888"
     CDS             complement(18316..18903)
                     /locus_tag="OPY25_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HCS0927515.1"
                     /translation="MNHVWGLFSHPDREMQVIKSENETVSHHYTHHVLLMAAIPVVCA
                     FIGTTQIGWNFGDGNVLQLSLFTAFALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LARCMVFAGYVATPLFLSGLVALYPLVWLCALVGAVALFYTGYLLYLGIPTFLNINRE
                     EGLSFSSSTLAIGVLVLEVLLAITVILWGYDYRLF"
     gene            19062..19631
                     /locus_tag="OPY25_001889"
     CDS             19062..19631
                     /locus_tag="OPY25_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCS0927516.1"
                     /translation="MDINTLITHYGYAALVIGSMAEGETVTLLGGVAAHQGLLKFPLV
                     AAAVALGGMMGDQLLYLLGRCYGGKILRRFPRYHTKIRRAQKMIQRHPYLFVIGTRFM
                     YGFRVVGPLLIGASRLPPKIFLPLNIVGALIWALLFTTLGYLGGEVIAPWLHDLDQHL
                     RHGVWLILAIVLVVGVRWWLKRRGKAEAR"
     gene            complement(19679..20440)
                     /locus_tag="OPY25_001890"
     CDS             complement(19679..20440)
                     /locus_tag="OPY25_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCS0927517.1"
                     /translation="MTKVAIVTASDSGIGKACALLLAQNGFDIGITWHSDERGAQETA
                     KKAAQFGVRAETIHLDLSQLPEGAQAIEHLIQRLGRVDVLVNNAGAMTKSAFIDMPFT
                     QWRQIFTVDVDGAFLCAQIAARHMIKQGEGGRIINITSVHEHTPLPQASAYTAAKHAL
                     GGLTKSMALELIEHHILVNAVAPGAIATPMNDMDDSDIEPGSEPSIPIARPGSTHEIA
                     SLVAWLCSEGASYTTGQSLIVDGGFMLVNPQFNAK"
     gene            complement(20506..21942)
                     /gene="mdtQ"
                     /locus_tag="OPY25_001891"
     CDS             complement(20506..21942)
                     /gene="mdtQ"
                     /locus_tag="OPY25_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HCS0927518.1"
                     /translation="MNRNSFLAATASLPLFILLAGCAPMHDTRQSLTQQTPSSHVDSS
                     LPAALKNGWPDSQWWKAYHDAQLDALIDNAIQHSPDMQVAEQRIQLAEAQAKAVEAQD
                     GPQLDFSADIERQRMSAEGLMGPFAITDPAAGTTGPWYTNGTFGLTAGWDLDLWGKNR
                     AEVTARIGAVKAREAEQEQTRQLLASGVARLYWEWQTQAALKNVLMQIEHEQQNVVAV
                     NRELYQHGITSSVEGVETDIDASKTQQQLNDVNGKMKVIEARLSALTNTQSAALKLRQ
                     VSLPAVESQLPSQLGYSLLARRADLQAAHWYIESSLSSIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQYGITGGLTLPIFDSGRLNANLDIAKAQSNLSIANYNKAVVDAV
                     NDVARAASQVETLAQKNQHQQQIEHDAQRVVGLAQARFNAGIIAGSRVSEAKIPALRE
                     QCNGLLLQGQWLDASIQLTSALGGGYHS"
     gene            22260..22343
                     /gene="yohP"
                     /locus_tag="OPY25_001892"
     CDS             22260..22343
                     /gene="yohP"
                     /locus_tag="OPY25_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HCS0927519.1"
                     /translation="MKILLWAILIIFLIGLLVVTGVFKMIF"
     gene            complement(22401..23339)
                     /gene="dusC"
                     /locus_tag="OPY25_001893"
     CDS             complement(22401..23339)
                     /gene="dusC"
                     /locus_tag="OPY25_001893"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HCS0927520.1"
                     /translation="MRVLLAPMEGVLDALVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELLHASRTPSGTPVRIQLLGQHPQWLAENAARATALGSYGVDLNCGCPSKV
                     VNGSGGGATLLTDPELIYQGAKAMRAAVPSHLPVTVKVRLGWDSGDRKFEIADAVQQA
                     GASELVVHGRTKAQGYRAEHIDWQAIGEIRQRLTIPVIANGEIWDWQSAQACMATSGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVTLLQKYTRLEKQGDTGLYHVARIKQW
                     LGYLRKEYIEATELFQSIRALNRSSEIARVIQAIKI"
     gene            complement(23448..24641)
                     /locus_tag="OPY25_001894"
     CDS             complement(23448..24641)
                     /locus_tag="OPY25_001894"
                     /EC_number="1.14.13.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybenzoate 6-monooxygenase"
                     /protein_id="HCS0927521.1"
                     /translation="MTHVTSAIIVGGGIGGAATALSLARQGIKVMLLEKAHEIGEIGA
                     GIQLGPNAFSALDSLGVGDVARQRAVFTDHITMMDAVNAEEVVRIETGQAFRDHFGGP
                     YAVIHRVDIHATVWEAVLTHPGVEYRTSTHIVDIRQTPDDVTVFDEQGNSWTADILVG
                     CDGVKSVVRQSLLGDAPRVTGHVVYRAVIDCDDMPDDLRINAPVLWAGPHCHLVHYPL
                     RGGQQYNLVVTFHSRQQEEWGVKDGSKEEVLSYFAGIHPRPRQMLDKPTSWRRWSTAD
                     REPVAKWGTERITLVGDAAHPVAQYMAQGACMALEDAVTLGKALERCDGDAQQAFALY
                     ESVRIPRTARIVWSTREMGRLYHAAGVERQVRNLLWKGKSQEAFYRGIEWLYGWKEDN
                     CLEPR"
     gene            complement(24656..25300)
                     /gene="maiA"
                     /locus_tag="OPY25_001895"
     CDS             complement(24656..25300)
                     /gene="maiA"
                     /locus_tag="OPY25_001895"
                     /EC_number="5.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maleylacetoacetate isomerase"
                     /protein_id="HCS0927522.1"
                     /translation="MKLYSFFNSSASYRVRIALALKGIDYQTVGVNIRIGQQNALAYR
                     RMNPVGLVPTLVTDDGESLGQSLAIVDWLDRHFPQTPLLPTSDPARSQALEIVYAIAC
                     DIHPINNMRVLRYLTDELKVSEEDKKRWYAHWIQQGLSAVEQLLRKSQSGRFCVGDAP
                     GLADCCLIPQWANALRMGCDLSGYPRCKAVYDACVQLPAFIAAAPENQQDKIPA"
     gene            complement(25309..26010)
                     /locus_tag="OPY25_001896"
     CDS             complement(25309..26010)
                     /locus_tag="OPY25_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HCS0927523.1"
                     /translation="MTKYVFQPQAPVTVPVAGSDEQFPVRRVYCVGRNYAAHAREMGF
                     DPDREPPFFFCKPADAVVPVAAGDTLELPYPAQTDNYHYEIELVVAIGKKGSDIPLEK
                     AHEYVWGYATGLDMTRRDRQMEMRQMGRPWEIGKAFDLSAPIAPLHKAAETHNVDNAP
                     IWLQVNGEDHQRSDIRHLIWSVNETISYLSGFFELQPGDLIFTGTPEGVGAVVKGDVI
                     TGNVEGLTPIAVKIV"
     gene            complement(26026..27063)
                     /gene="gtdA"
                     /locus_tag="OPY25_001897"
     CDS             complement(26026..27063)
                     /gene="gtdA"
                     /locus_tag="OPY25_001897"
                     /EC_number="1.13.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gentisate 1,2-dioxygenase"
                     /protein_id="HCS0927524.1"
                     /translation="MSEINQNVKDSRQQYYQHISGQNLTPLWESLHHLVPQTPNANCA
                     PAYWNYQEIRPLLMESGNVIGAKEAIRRVLVLENPALRGQSSITATLYAGLQLILPGE
                     VAPSHRHNQSALRFIVEGKGAFTAVDGERTPMHTGDFILTPQWRWHDHGNPGSEPVVW
                     LDGLDLPLVNLLGCGFAEDYPEDQQPVTRKEGDYLPRYAANMLPLRHQRGNSSPIFNY
                     RYDRSREALHDLTRMGDPDEWEGYKLRYVNPVTGGYPMPSMGAFLQLLPKGFASRVAR
                     STDSTIYHVVEGAGQVTIGNETFHFSAKDIFVAPTWHEVSFRSSEDTVLFSFSDKPVQ
                     EALGLFREARY"
     gene            complement(27075..28433)
                     /locus_tag="OPY25_001898"
     CDS             complement(27075..28433)
                     /locus_tag="OPY25_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid/H+ symport family MFS transporter"
                     /protein_id="HCS0927525.1"
                     /translation="MTQRRDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFI
                     APDIRTHWQLSASELAPLFGAGLLGLTAGALLCGPLADRFGRKRVIELCVALFGALSL
                     LSAFSPDIETLVLLRFLTGLGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSA
                     MGGIVSAQLVPLIGWHGILALGGILPLMLFFGLLFALPESPRWQVRRQLPQAVVARTV
                     SAITGERYHDTQFFLHETAAVAKGSIRQLFAGRQLVITLMLWVVFFMSLLIIYLLSSW
                     MPTLLNHRGIDLQQASWVTAAFQVGGTLGALLLGVLMDRLNPFRVLAVSYALGAVCIV
                     MIGLSENGLWLMALAIFGTGIGISGSQVGLNALTATLYPTQSRATGVSWSNAIGRCGA
                     IVGSLSGGMMMALNFSFDTLFFVIAIPAAISAVMLTLLTVVVRLSISVPDDLPRASVV
                     NE"
     gene            28559..29467
                     /locus_tag="OPY25_001899"
     CDS             28559..29467
                     /locus_tag="OPY25_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0927526.1"
                     /translation="MANWAQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLS
                     QLEDEIGITLFERHSKGLRPSEGGKLLLQHAQRLINDLERSQYEIARFKQGGLVGSLK
                     IGCSPVATDCVSQAILSLLNEMPTLHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRAL
                     QLPLNYQVLYTEPVCFVARPHHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALV
                     DNGVMLPENTIESASMNVSTNLLQSSDMISILSLRLAQRYASQGQLAILNLPKIEQKG
                     SVGMFWRKNETPSLALSRFLYFLAQV"
     gene            29599..29997
                     /locus_tag="OPY25_001900"
     CDS             29599..29997
                     /locus_tag="OPY25_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCS0927527.1"
                     /translation="MSKSLNIIWQYIRAFVLIYACLYAGIFLASLLPITIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAI
                     STLVVFVVVSWSSHLIHGERKVVGQKGTKK"
     gene            29994..30689
                     /locus_tag="OPY25_001901"
     CDS             29994..30689
                     /locus_tag="OPY25_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HCS0927528.1"
                     /translation="MMTYIWWSLPLTLAVFFAARRLAAHFKMPLLNPLLVAMVVIIPF
                     LLLTGIPYEHYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIISICFVGSLVA
                     MITGTSVALLMGATPEIAASVLPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMHIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVICGIITSLV
                     APFLFPLILAVMR"
     gene            30843..31727
                     /gene="cdd"
                     /locus_tag="OPY25_001902"
     CDS             30843..31727
                     /gene="cdd"
                     /locus_tag="OPY25_001902"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCS0927529.1"
                     /translation="MHPRFQTAFAQLADNLQSALAPILADHHFPAMLTAEQVSTLKNT
                     AGLDEDALAFALLPLAAACARTDLSHFNVGAIARGVSGNWYFGANMEFLGATMQQTVH
                     AEQSAISHAWLRGEKGLAAVTVNYTPCGHCRQFMNELNSGLDLRIHLPGRAPHTLRDY
                     LPDAFGPKDLEIKTLLMDEQDHGFTLTGNTLTQAAITAANKSHMPYSHSPSGVALECK
                     DGRIFTGSYAENAAFNPTLPPLQGALNLLSLNGYDYADIQRAILAEKGDAALIQWDAT
                     AATLKALGCHNIDRVLLG"
     gene            31904..32623
                     /gene="sanA"
                     /locus_tag="OPY25_001903"
     CDS             31904..32623
                     /gene="sanA"
                     /locus_tag="OPY25_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HCS0927530.1"
                     /translation="MLKRVFYSLLVLVGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRKGVINQYYRYRIQGALNAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPADIVLDYAGFRTLDSIVRTRKVFDINDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKNMLTVRLREFGARFSALADLYIFKREPRFLGPLVPIPTQHQVPND
                     AQGYPAVTPEQLLELEKKKGK"
     gene            32620..>32767
                     /locus_tag="OPY25_001904"
     CDS             32620..>32767
                     /locus_tag="OPY25_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HCS0927531.1"
                     /translation="MIMDVQTIFVILAFLLLPLFCFREAWKGWRTGAVDKVVKNARKP
                     VYVYR"
BASE COUNT         7676 a         9281 c         8416 g         7394 t
ORIGIN      
        1 tgccgattat ttcagataaa cacctgtctg tttaagcagg aattaacaat gcgggggcta
       61 ttattttatt aatacattca ctgcatcaat atatattaat gcagtgaatg tcatattctc
      121 tttggaatac gtcaggagga ttacaccgcg cggaaggcga tttctcccgg aatcacttca
      181 ccctgccagt aaagctgtgc cgcaacgcga tcggccagtt cgcgatagat cgcggtaaac
      241 tcgctctccg gacggctaac caccgtcggc gtaccgcgat cgagatcttc acgcagacta
      301 atatgcagcg gcatctgacc cagaagctga gtatggtatt tttccgccag cttctgcgcg
      361 ccgcccgtgc cgaagatcgg ttcgtgatgg ccgcagttgc tacaaatatg catactcata
      421 ttttccacaa tgccgagcac cggcacttcc accttctcga acatcacgat accttttttg
      481 gcgtcgatta gcgcgatatc ctgcggcgta gtcaccacca ccgcgccggt aacaggaatg
      541 ttctgcgcca gcgttagctg aatatccccg gttcccggcg gcatatccag taccagataa
      601 tccagatccg gccacagcgt ctcctgcaac atctgcatca gcgccttact ggccattggg
      661 ccgcgccata ccatcgcgtt atcgtcagtc accagatagc cgatcgagtt ggtcgccagg
      721 ccgtgagaca taatcggcgc catatgcgta ccgtctggcg atgtcgggcg ctgatcttct
      781 gcgccaagca tggttgggat cgacggaccg taaatatcgg catcgagaac cccgaccttt
      841 gcgccttcag cctctaacgc cagcgccagg tttaccgccg tggacgattt acccaccccg
      901 cctttaccgg agctcacggc aatgatgttt ttcacgccat taatgccagg ctgatttttg
      961 acgcgtttca gcgtcgcaat gttgtacgac agtttccagt cgatcgcttt tgcgcccgta
     1021 atacgtaaca gatcggcgct gcattgctct tttaatacct caaacgcgct gttccagacg
     1081 aacggcatga ccagctcaac gtgcagcgta tcatccatcc aggcgacgtg gtgcaacgcc
     1141 ttaagcgtgg tgaggttatg cttcagggtt gggtgctgaa aattcgccag cgtcccggcg
     1201 accatcgctc gcagggtatc tggtgatttg gcctgggatt gttcgttcat cccgactcct
     1261 tttgtagttc tgaaaagtac gattgtaact ttgtagttta ctccagcggt aacaattatt
     1321 catttacgga taaatgccct tatcgattgg cgcagtaatt accattttgg tactatcaaa
     1381 gccctttttt acaacagaag aagtaatacc cactatgact caagtcgcga agaaaattct
     1441 ggtaacgtgc gcgctgccgt acgccaacgg ctctatccac ctcggccata tgctggagca
     1501 catccaggct gatgtctggg tccgttacca gcgaatgcgc ggccatgagg ttaacttcat
     1561 ctgtgccgat gacgctcatg gcacgccgat catgctgaaa gcgcagcagc ttggtattac
     1621 accggagcaa atgatcggtg aaatgagcca ggagcaccag accgatttcg ccggttttaa
     1681 tattagctac gacaactacc actcaacgca cagcgacgag aatcgcgagc tgtccgagct
     1741 gatttatacg cgcctgaaag agaacggttt tattaagaac cgcaccatct ctcaactcta
     1801 cgatccggaa aaaggcatgt tcctgccgga tcgatttgtg aaaggcacct gcccgaaatg
     1861 taaatccgcg gaccagtacg gcgataactg tgaagtctgc ggcgcaactt acagcccgac
     1921 cgaacttatc gagccgaaat ccgtggtgtc cggcgcgacg ccggtaatgc gtgactccga
     1981 gcactttttc tttgacctgc cgtcattcag cgaaatgttg caggcgtgga cccgcagcgg
     2041 cgcgctgcag gagcaggtgg cgaacaaaat gcaggagtgg tttgaatccg gcctccagca
     2101 gtgggacatt tcccgcgacg cgccgtattt tggtttcgaa atcccgaacg cgccgggcaa
     2161 atatttctac gtctggctgg acgcgccgat tggctatatg ggctccttca aaaatctgtg
     2221 cgataagcgc ggtgacacga ccagttttga tgagtactgg aaaaaagact ccgacgccga
     2281 gctgtatcac tttatcggca aagacatcgt ctatttccac agcctgttct ggcctgccat
     2341 gctggaaggc agccacttcc gtaagccgac caacctgttc gttcacggtt acgtgacggt
     2401 gaacggcgcg aagatgtcta agtctcgcgg cacctttatt aaggccagca cctggctgaa
     2461 acactttgac gccgacagcc tgcgctacta ctacaccgcg aagctttctt cacgcattga
     2521 tgacatcgac ctgaacctgg aagactttgt ccagcgcgtc aatgccgata tcgtcaataa
     2581 agtagtcaac ctggcatccc gtaacgccgg ttttatcaat aagcgtttcg acggcgtgct
     2641 ggcggctgaa ctggccgatc cgcaattgta caaaaccttt actgacgccg ctgcggtgat
     2701 tggcgaagca tgggaaagcc gtgaattcgg taaagctatc cgtgagatta tggcgctggc
     2761 cgacgtcgct aaccgttatg ttgacgagca agcgccgtgg gtggtggcta aacaggaagg
     2821 ccgcgacgct gacctgcagg ccatttgctc gatgggcatc aacctgttcc gcgtgctgat
     2881 gacgtatctg aaaccggtac tgccgacgct ttctgaacgc gttgaagcct tcctgaacag
     2941 cgaactgaac tgggatgcca tcgaacagcc gctgctcagt cacaaggtca acacctttaa
     3001 ggcgctctac aatcgcatcg acatgaagca agttgaagcg ctggttgaag cgtctaaaga
     3061 agaggtgaaa gccgcagccg cgccggttac cggcccgtta gccgacttcc cgattcagga
     3121 aaccatcacc tttgacgatt tcgccaaaat tgacctgcgc gtagcattga ttgaaaacgc
     3181 tgagttcgta gatggttctg acaaattgct gcgtctgacg ctggatctgg gcggcgagaa
     3241 gcgtaacgtc ttctccggca ttcgttccgc ctacccggac ccgcaggcgc tgatcggccg
     3301 ccagacggta atggtcgcca acctcgcgcc gcgcaaaatg cgctttggcg tctccgaggg
     3361 aatggtgatg gccgcaggac ctggcgggaa agatatcttc ctgttaagcc ctgatgacgg
     3421 cgcgaagcct ggccaacagg tgaaataagc aacaagccgg agcatgctcc ggctttttta
     3481 accgcttaat cctgactggc atatcacccc atccgcgtgt tttaactttt tccttaataa
     3541 gcaatagcgt taagactcca tatccggact gctaaataac ggctaaaagt catattctat
     3601 ctctccctga tacattgcta ttactgggtt aaattaattc attgaaatta ttttaaaaac
     3661 ccaatcatta tataaaatgg agttttagat gaaaatttct ggcaagttat tgtccgcggc
     3721 tttggcttcc gtactggtgt tctctcttgc tggctgtggc gataaagaag aatcaaagac
     3781 ctttaacgca aacctggcgg ggacagaaat ttcaattact tacacctata aaggtgacaa
     3841 aatcattaag cagacgtctg aaagtaaaat cagctatgcc actgtaggcg ctaaaacgaa
     3901 agaagatgcc gccaaaattc tcgatccgct gagcgcgaaa tataaaaata tcgccggagt
     3961 ggaagaaaaa ttaacctatg aagataccta tgcccaggaa aacgtctctg tggatatgga
     4021 aaaagtggac tttaaagcgt tacagcaaat ctcagggacg atggtgtccg gcgataccag
     4081 caaaggtatc agcatgaaac aaacccagac gctgctggaa gctgctggtt ttaaagaagc
     4141 gaaataactg gcaggcataa tgtattgcat cgactggtaa agtcgctcag ggcgctgctt
     4201 cggcagcgtc ttttctttat gaattccgaa aaaagacagc ctcgctgtaa gtcccctcgc
     4261 caaagcctat aatccctgaa ttcctggcca caccaatact taacgacaag gaattgttat
     4321 gcaggttcta cgtcttatgg cactgccact attcgcgctc tctctatcgg ttagcataac
     4381 tggctgcgat cagaaaaacg atactctcca gggaaagcaa aataacatga cagcgtttat
     4441 caagaagata gccgctagca aagagtcaga ggaaacacaa cgctatgtag gtaatctcaa
     4501 cggtattgaa atcaagttaa cctattacta caaaggggat atcgttttac gtcaaatatc
     4561 tgaacataaa ctactttata agaccctgaa agccaataat aaagaagaag cacaaaaaat
     4621 gctgagtcaa gtcggcgaag cttatcaggg tatgccgggt ttgactgaac gaatcgacta
     4681 ttatgatagc tatgctacgg aatatgtgga tattgatttt acccaggcaa aaataagcga
     4741 cctctgtaaa ttgccaggat catcaattga caactgttcc gcgtactatc tgtcaatgat
     4801 tcgctcgcag aaactgttgg aagagagcgg gtatcataga atcaattagt ataataatgc
     4861 gttttcccgg tcagacagga cgctgccggg aacaataccg cagaattact tcgccgcgtg
     4921 ttcacgggcc gccagaccgc gcagaaaata acgcataaac tgatcgccgc attcgcggaa
     4981 gttcttatgg tccggcgcgc gcatcatcgc ggtgatctct ggcattgaga cacgaaacaa
     5041 ctgaccggta agtatcgcca ggatatcatc tgtttttagc gaaaaggcaa tacgcagctt
     5101 tttcagcaca atattgttgt tgatacgacg ttccgccgtc aatgcaggcg ccgcctcatc
     5161 tttgccgcgt ttttcataaa tgaggccatt gagaaatgag gacaacacga tatccgggca
     5221 acgctgaaac ccctcttcct cttctttgcg caaccagatt gctatctgct ccggcgtagc
     5281 atcaacgtta cccagcgcca ggatacgcgc cagatcggta ttattagctt ttaaaatgta
     5341 gcgcacgcta cgcagaatat cgttactcag catgaggcct tcggtcgttt ctatggcaaa
     5401 acgatattct aacagtcttt tacaggccaa tcgcctcttt taaacttttc agatagcgac
     5461 ggcttaccgg caccgtcagg ccgttgcgta aaatcagctc tgcctgccca ttatcctcca
     5521 gccgaatttc ctgcaaatgg gccatattca ccagaaactg acgatgacaa cgcagtagcg
     5581 gcgtccggct ttccagcgtg cgcagcgtca gctcggtaaa cccctctttc ccttcactgc
     5641 tggtcacata aacgccgctc atacggctac tgacaaaggc gacatcatcc atttgcaaca
     5701 aatagatccg gctgtgtccg gtacagggaa tgaatttaag cgcctgctgg ttttccggca
     5761 acaacgaaac atcctgttta ctgcgctcct gacgcagacg atgtaacgtt ttttccagcc
     5821 gtttctcctc tatcggcttg agcagataat caaaagcgtg ttcttcaaag gctttgatgg
     5881 cgtattcgtc aaacgcggtt aaaaaaacga tatacgggcg gtgttccgga tcaagcattc
     5941 ctactatctc cagtccactg atacgcggca tctgaatatc cagaaacagc acatcaggtc
     6001 gcaacttatg taccgcgcca atcgcttcta ccgcgttcgc gcactctccc acaatctcaa
     6061 tgtcatcctg cccctggagc aaaatccgca gattttcccg cgctaacggc tcatcatcca
     6121 caatcagcac tttaatcatg cgtcctcctc cagtggaagt cgtaatgtaa ttcgggtaaa
     6181 acagtccggc tcgcaggcca cgctaatacc ataatcatcg ccaaagtgtt cgcgcagacg
     6241 tttatccacc agactcatcc ccagcccgct actgccggcg gaaggctgat acagtcccgc
     6301 attatcttca atatctaaca tcaaatgctg cccttcgcgc cgggcgcgaa tagcgacgtt
     6361 gccggtatca agcagttgcg acgtgccatg tttaatggcg ttctcaacaa tcggctgtaa
     6421 tgtaaacgca ggcaatttct gacgtgaaag cgtcgatgga acatcaagct gtacctgcag
     6481 acgcgactga aaacgcgctt tttcaatttg caggtaagcg ttcacgtgtt caatttcatc
     6541 cgccagcgtg acgatttccg acgggcgttt taaatttttg cgaaaaaagg tcgacaagta
     6601 ctgcaccagt tggctggcct gttcgctgtc gcggcgaatc accgctttaa tggtattgag
     6661 cgcattaaac agaaaatgcg gattcacctg cgcgtgcaac agcttgatct ctgactgcgt
     6721 cagcaacgcc ttctgccgtt catactgccc ggccaggatc tgcgcggata aaagctgcgc
     6781 aataccctcc cccagagtac ggttaattga gctgaacagt cggtttttcg cttcgtacaa
     6841 tttaatggtg cccatgactc gctgattttc gccacgcagc gggatcacca gcgtcgagcc
     6901 gagtttacac tgcgggtgta gcgaacagcg atacggcact tcgttgccat cggcataaac
     6961 cacctctccg gtttcaattg ctttcagcgt ataacctgat gaaatgggtt tgcccggtag
     7021 atggtgatcg tcgccaatac cagtaaaagc cagcagtttt tcgcgatcgg tgatggcgac
     7081 ggcgccaata tccagctcct gatataacac ctgcgccacc ttcatactgt tcacttcgtt
     7141 aaatccctga cgcagaatcc cctccgttga cgcggcgacc ttcagcgcgg taacagaaaa
     7201 tgccgaagta tatttttcga acatggcgcg cttatcgagc aaaatacgca taaacagcgc
     7261 ggcgccaacg gtattcgtca ccatcatcgg cgcggcaata ttactgacca gatgcagggc
     7321 atcgtcaaac ggcctggcta tcagtaaaat gatcagcatc tgcaccagtt cggcaacaca
     7381 cgtaattgct cccgccgtca gcgggctaaa cactttgtcc gggcgtccgc gacgtatgag
     7441 aacgctgtgt accaacccgc ccagcagccc ttcgacgatg gtggaaatca tacagctcag
     7501 cgccgtcatg ccgcccatag aataccgatg taacccaccg gtcagaccga ccagcccgcc
     7561 gacgaccggc ccgccgagta ggccgcccat caccgcgcca atcgcgcggg tattggcaat
     7621 cgaatcttcg atatgtagcc caaaataagt gcccataatg cagaagatag aaaacgtgac
     7681 ataacacaga agcttgtgcg gcagacgaac cgtgacctgc ataagcggga tgaacaggcg
     7741 cgttttactc attagccacg caatgaccag aaacacgcac atctgctgaa gcagcagcaa
     7801 caccagatta aactcgtaca tacccgcaaa ccacacttca attaaaagcg cgtaacatac
     7861 attgagtacg attaactttc tttgaactgt tgcataaaaa tatgaattcg tgaatacgat
     7921 cacttaaacg ccgcgccgca acccgctact tcgcgtttta atgcataaaa aacaggcaaa
     7981 acttcctggt tcctaaaaga gcgtctaaag ttaaaccggg acctcgcgag caagggtgaa
     8041 acgatggcgc tttacacaat tggtgaagtg gctttgcttt gtgatatcaa tcctgtcacg
     8101 ttgcgcgcgt ggcagagacg ttatggactt ttaaaaccac agcgaacgga tggcggtcat
     8161 cgtctgttta acgatgccga tatcgacaga atccgcgaaa tcaagcgctg gatagataac
     8221 ggcgtccagg tcagcaaagt caaagtgctg ctcagtagcg acagtagcga acaacctaac
     8281 ggctggcgcg aacagcagga gatcctgctg cactacctgc aaagcagtaa tctgcacagt
     8341 ttacggttat gggtcaaaga acgcggtcag gattatcctg cccaaacatt gaccactaac
     8401 ctgttcgtcc cactgcggcg acgattacag tgccaacaac ccgcccttca ggcgctgctc
     8461 ggcattcttg acggtatcct gatcaactat attgcgctct gcctggcgtc tgcgcgtaag
     8521 aaacagggaa aagatgcgtt ggtgatcggc tggaatatcc atgataccac ccgcctgtgg
     8581 ctggaaggtt gggtcgccag ccaacaggga tggcgaatcg acgtgttggc gcattcgctt
     8641 agccagttcc gcccggaact ttttgacggc aagacgttac tggtatggtg cggagaacac
     8701 cagacgctgg cgcagcagca gcaactcctg gcatggcgcg cccagggaca cgacattcat
     8761 ccccttggcg tttaaacagc agctaacaaa ttcgctttaa tgtatactcc ttttattaac
     8821 ataaggagta cataatgcgc gtagcgaaaa tcggggtgat cgcccttttc ctgctgatgg
     8881 ctattggcgg tatcggcggc gtgatgctgg caggttacag ttttattttg cgtgccgggt
     8941 aagcgcgcgc gtcagccttt caaacaggcg atcgataatg atcgccgcca gcgccaccag
     9001 cagcgccccc tggataacat aggccgtatt aaagccgcta agcccgataa tgatcggcgt
     9061 gcctaacgta ctggccccca ccgttgaagc gatggtcgcc gtaccaatat tgataatcac
     9121 cgaggttcgg atgcccgcca gaatcaccgg cgcggccagc ggcagctcaa cctgatacaa
     9181 ctgttggcga cggctcattc ccataccgct ggcaacgctc atcacgctgg caggcaccgc
     9241 gcccagcccg gccagggtcg cctgcaggat gggcaacacc ccatacagga tcaaggcgat
     9301 aatggccggt tgctgaccaa aacccatgac gggtaccgcg atcgccagta ccgcgaccgg
     9361 cggaaaggtc tgcccgacgg cggcgatagt ctccactagg ggacgaaact ctttcccact
     9421 ttctcgcgtg accgcaatcc ctgcgccgac gcccaccacg acggcaaaca aacttgagat
     9481 gcccaccaac cagaaatggg cgagcgcgag ggcggcaaaa ctctcctgtt ggtagaccgg
     9541 gcgcggtaaa tcgggaaaca gcgcggcgaa gaacggctgg ctataaggca atccaaacag
     9601 cagaagcaag aacagaacaa taagccagag aagcggatca cacagtcgtt tcacgggggg
     9661 acgtctccga aagcagatcg cggaaatgga gcgtaccgca gggctcgccc tgctgattcg
     9721 ccaccggcag gacgtcgcac cgacgggcga caaacatcga tagcgcatcg cgtagcgtca
     9781 tctcttccac cagcgcgtcg ccgctgagct gttcatgccg acgtacataa tcgcctacgc
     9841 tacgtaacga aagcagcctt acgcccagct cgctgcggcc aaaaaatgcc tgcacgaaat
     9901 cattttccgg cgaggtcagc atagaaagtg gcgatccctg ttggataacg tggcccccgt
     9961 ccatcagcac cagatggtcg gcgaggcgta gcgcctcgtc gatgtcgtgc gtcaccagta
    10021 cgatggtgcg ccccagtagc tgatgaatgc gggtcatctc ctgctgcaat gcgccgcgcg
    10081 ttaccggatc aagcgcgccg aaaggctcgt ccatcagcaa tacctgcgga tcggcagcca
    10141 gcgcccgcgc aacgccgacc cgctgctgtt gcccgccgga aagctgatgc ggatagcgat
    10201 cgcgcagcgc gctttccaga cccaataatg ccatcagttc atcaatacga tcgttaatcc
    10261 gcgcacgcga ccacttttgt agttgcggta cggtggcgat attttgcgcc accgtccagt
    10321 ggggaaaaag gccgatagac tgaatggcat agcccatgcg acggcgcagt tcaagcaccg
    10381 gcaggctgcg gatctcttca ccggcaaaac ggatcgttcc gctatcatgc tctaccagcc
    10441 ggttaatcat cttcagagtg gtcgattttc ccgaaccgga ggtgccaatt aacaccgaaa
    10501 agctgccttc gctaaagtgc aaattgaggt cgctaacagc ctgttgatcg ccgaaggttt
    10561 tactgacatg gttaaattca atcatcggtt gctcccttca aaaacgcgat ccataaatca
    10621 aacagcgcgt cgatcactac cgccagcgca atcaccggaa tgacgcccaa caggactaaa
    10681 tcaatggcgc tgctcaatag cccctgaaac accagcgcgc cgaaacctcc cgcgccaatc
    10741 agcgcggcgg cgacggccat tcccactgtc tggaccatta ctacccgcag gctacgtaaa
    10801 aagaccggca gcgccagcgg cagttgcaca tgcctgaagc gctggccgct actcattccc
    10861 attgctcttg cgctctccag cacatcgcgt ggcacctgat tgagcccggc gaccacgccg
    10921 cgcaccagcg gcaataacgc atagagcacc agcgctatca gcgcaggcgt catgccggtt
    10981 cccgcgacgc cgaattcggc aagccacgga aactgtttca ccagcccggc caacggcgcg
    11041 atcagcaggc caaacagcgc gacggaagga atagtctgga tcacattcag tacggtaaac
    11101 accggcccct ggcgtgaggc ggaaaaataa caccagacgc ccaacggtag tccgatcgcc
    11161 agcgccggca gcaccgtgcc cgccagtaac attaaatgtt gcaccagcgc ggcatcgaaa
    11221 acatcctggc ggttggtata ctctttcaga agcgagaggt tgtcgaacgt gcctgaaaac
    11281 agcagcgcca gcgggacaat gacaatttgc gcgtgcagca accagcgcca cagcggccca
    11341 acggtaatac ggcggatcgc atcgctacag gccagcagca tcagaccgag gcccagccac
    11401 aatccacttc ccagactggt acgcgccagc ggactgccct cctgcgccaa ctgggtcgcc
    11461 gccctgccga ctccccacag catgacaata aaaagcgtct gcgccatcat cagcgtcagt
    11521 acgctaccgc gtttaccggg cacaaagcac agcgtaaaca gcgcgcatcc cgcgccagtc
    11581 agcatccaga tggtcgccgg ccagatctcc cataactggc gcccctcgcc gctcaccaga
    11641 cgattcgggg cgtaattaat gaaaggcagc gcgacagcaa gcagggccag aacaaccaac
    11701 agcaacagca cacgattaac cgtaattttt ttggcagcgt cactcacaga ttacttcacc
    11761 cacccttttt gtcggaggta atctgcggcg acttttttcg catccagccc ttctacggcg
    11821 attctggcgt tcaactgttg cagcgttttc tcatcaaggc tggcgaaaac gggctgcagc
    11881 caatcggcta tctgcggata ggcctgtaac accgattcac gcactaccgg cgcgggggca
    11941 tagataggct ggacgccttt cgggtcgctc agggtttgca gacccagcgc ggcgaccggg
    12001 ccgtcggtgc catacgccat cgcggcgtta acaccggatg tttgttgcgc ggcggctttg
    12061 atcgtgaccg ccgtatcgcc gcccgccagc gacaagagct ggttctgatt caaggtaaaa
    12121 tcataggctt tttcaaatgc cggcagcgca tccgaccgtt cgataaattc cgcagacgcc
    12181 gccagtttaa aagtgccgcc ctctttcaga taacggctga gatcggcaag cgaggagagt
    12241 ttattttttt ccgcgatgtc ctgacgtatc gcgatggtcc aggtgttgtt ggccggcgca
    12301 ggcgtcaacc agaccagctt attctgctcc gcatccagtt ttttgacttt ctcaaagcct
    12361 tgctttgcat ttttccatgc cggatcgttt tcatctttaa aaaagaacgc cccgttaccg
    12421 gtgtattccg gatagatatc cagctctccg gcggtaatcg cgccacgaac gactggcgtc
    12481 gtcccgagct gaattttatt gaccgtttta acgccgtggc tttccagtac ctgcaaaatc
    12541 atgttgccga gcagtgcgcc ttcggtatca atctttgacc cgaccgtcac gggcgatgcc
    12601 gcctgtagag gtaaactcac cgtcgccagc aacgccagcg aacttaccca tagctttgag
    12661 atcgtcatga tgctttcctc atccttttac ggcctttttc agaaacttga gaaaaaagca
    12721 tagttgaaaa gtctgcgttt aacctgggat tttccggcag tttaagtgac gtggcaggca
    12781 ataaaagggg gggacagaaa aagtcattgc cagacagggc gctgctatcg cgccctgttg
    12841 acggcaggct tacagtagct cgaacgatcc ttgtttaacg cgagcggaat ccacgccgat
    12901 aaagacgttg aacttgccgg gttccgcgtc atatttcatc tgctgattcc agaacttcaa
    12961 cgcctcgata tcaatcggga aactcacggt tttacgttcg ccgggcttga gggtgatttt
    13021 ttcaaagcct tttaattgct tcaccgggcg gctcatcgac gccgtgacat cctgtaagta
    13081 catctggatg accgtttccc cttcgcgttt accggtattc gtgacctcta cgctggccgt
    13141 gactttgccg tcgcgttgca ttgtcggtga ggagagcgtg acgtcagaca ccgtaaatgt
    13201 ggtgtagctc agaccgtaac caaacggata gagcgggcca ttcgcttcgt caaaatagcg
    13261 tgaggtgtat ttgtttggct tttcaggatt atacgggcgt cccgtattga gatggctata
    13321 atagaccgga atttgtccca ccgaacgcgg gaaggagatc ggcagtttgc ctgacgggtt
    13381 gtaatcgcca aacagcacat cggcaatggc gttgccgcct tccgtcccgg caaaccaggt
    13441 ctccagaatc gcatcggctt gttgatcttc ttttaccagc gccagcggtc tgccgttcat
    13501 taataccagt accagcggct taccggtggc tttcagagcg gtgattaagt cgcgctgact
    13561 ctgcggaatg gtgatattgg tacgactgga ggcttcatgc gccatcccct gcgactcgcc
    13621 taccactgcg accactacat cggcctgttt cgccgcctgc accgcctcat caatcatcgc
    13681 ctgcggtgag cgcggatcga ttttcaccgc ctcttcatac aggtttaaga aatcgacgat
    13741 atctttatcg ttagtgatat tcgccccttt ggcatagagg atcttcgccc cgtcaccgac
    13801 ggcattttga atacccgcca gcaccgtcac tgactgattc gcgaccccag cagcagacca
    13861 gcttcccatt acatcacgtt gactgtcggc cagcggccca acaacggcaa tggtgcccga
    13921 ttttttcagc ggcagcgttt ccagccggtt tttcagcaga accacacttt cccgcgccac
    13981 ttcccgtgcc tctttacgat gcaggcggct ttcggcattg gtgtccaccg ggtcgctctc
    14041 tttcggtccc agatggctat aggggtcgtt aaacaatccc atgtcatatt ttacgttgag
    14101 cacatggcgc gtcgcgtcgt ccagttccgc catcgtcact ttgcccgact taatcagacc
    14161 cggcagatat ttgctgtaat actcatccgc catgctcata tccacccctg cctttagcgc
    14221 cacgcgcacc gcatcttccg ggtcggccgc ggtaccgtgt ttaatcagtt ctttaatagc
    14281 gccgtggtcg gaaacggtaa ttcccttaaa gccccactca tcgcgcagga catctttcaa
    14341 tagccaggaa tctgacgtcg caggcgtgcc gttcagcgag ttcagcgcca ccatcaccgc
    14401 gccgctcccc gcatccagcc ccgctttgta cggcggcatg tagtcattaa acagacgctg
    14461 ggaactcata tccacggtgt tgtattcttt accgccttca acggcgccat aggcggcaaa
    14521 atgtttcacg ctggtcatca ccgaatagcg gtccgccggg cttttgccct gcatcgcttt
    14581 caccatggtt tcgcccatga tggaggttaa atatgtatct tcgccaaagc cttcggaggc
    14641 gcgtccccaa cgcggatcgc gggagacatc caccatcggc gcccaagtca tattcagacc
    14701 gtcgtccgcc gcttcatacg ccgatacgcg tcctacggtt cttaccgcat ccagattaaa
    14761 agaagaagcc agaccgaggc ttatcgggaa gacggttcgc tggccgtgta ccacgtcata
    14821 agcaaaaaag agaggaattt tcaggcggct caatgccatc acctgatcct gcatttgacg
    14881 gatatcctgg cgggtgacgg tattgaaaat cgcccctacc tgcccgtctt tgatcatctc
    14941 gcgaatcgct tctttcgggt tatcagggcc gacgctaatc agacgtaact gaccaatttt
    15001 ttcatcgaca gtcattttct tgagtaaatc cgtgacgaac gcgtcgcgcg cttcgggcgt
    15061 cagcgggtga ttgccaaaca ggttttccgc caatgctggc tgcatcgcca gactcacagc
    15121 aacacctact gaacataacc atttcatgtt gagtctctct ttatctttat cccgacgagg
    15181 cggtaaaaac agaataaaaa ccgcagtttg ccataagcct aaacgcgaga ggagaagaaa
    15241 gcgaaggtta ttctcctaat tttccgcaca gtcgaatacg caaccgccag caaatggtat
    15301 caaggcggca aatgaatacc accaacacag aaacaatttg aatgagaaag cgtattgtca
    15361 tacaaagcgc tatgcttaac gctgatattt tgtcccacca caaggagtgg agaatgtctt
    15421 ccataacaat gactgataat aaaacgttcc tgaatgagct ggcccgcctg gtaggccatt
    15481 ctcacctgct gacagacccc gccaaaaccg cccgctatcg caagggtttc cgttccggtc
    15541 agggcgacgc gctggccgtt gttttcccgg gttcattact ggaactgtgg cgtgtgctca
    15601 acgcctgcgt taacgctgac aaaattattc tgatgcaggc cgccaacacc ggtctgacgg
    15661 aaggctccac gccgaacggc aacgactacg atcgcgatat tgtgattatc agcacccagc
    15721 ggctggataa gctgcactta ctggataacg gccaacaggt tctggcctgg cccggtacga
    15781 cgctctatgc gctggaaaaa gcgcttaaac cgctgggccg tgaaccgcac tcggtgattg
    15841 gttcgtcgtg tatcggcgcg tcggtcatcg gcggcatctg taataactcc ggcggctcgc
    15901 tggtgcagcg cggcccggcc tataccgaga tgtcgctctt tgcccgtatt gacgagcaag
    15961 gcaaactgca actggtcaat catctgggta tcgatcttgg gcatacgccg gagcagatcc
    16021 tgagcaagct ggatgatgaa cggattaaag atgaggatgt gcgtcacgat ggtcgtcatg
    16081 cgcacgatca cgactacgtg acgcgggtac gagatatcaa cgccgatacg cccgcccgct
    16141 ataacgccga cccggaccgt ttgtttgaat cttccggctg cgccggaaaa ctggcggttt
    16201 ttgccgttcg ccttgatacc tttgcagcgg aaaaaaatca gcaggttttt tatatcggca
    16261 ccaatcagcc cgcggtactg actgaaatcc gtcggcatat tctggcgaac ttcgacaatc
    16321 tgccagtggc gggagaatat atgcatcgcg atatctacga tattgcggag cagtacggta
    16381 aagatacctt tctgatgatc gataaactcg gcaccgacaa gatgccattc tttttcacgc
    16441 taaaaggccg aaccgatgcg atgctggaaa aagtaaaatt tttccgaccg catttcaccg
    16501 accgcgcgat gcagaaattc ggccatctgt ttcccagcca tctgccgccg cgaatgaaaa
    16561 actggcgcga taaatatgag catcatctgc tgttaaaaat ggcgggagac ggcgtcgcag
    16621 aagcgcaacg ctggctgaat gaatttttta aatccgctga gggcggtttc ttcacctgta
    16681 cgccggaaga aggcagcaaa gccttcctgc accgcttcgc cgctgctggc gcagcgattc
    16741 gttatcaggc cgtacacgct gatgaagtgg aagatattct ggcgctggat atcgccctgc
    16801 gccgcaacga taccgactgg ttcgagcatc tgccgccgga aatcgacagc caactggtac
    16861 ataaactcta ttacggtcac tttatgtgcc acgtttttca tcaggactat atcgtgaaga
    16921 aaggcgtcga cgtccatgcg ctgaaagcgc aaatgctgga gctgttgcag gcgcgcgggg
    16981 cacaataccc ggcggagcac aacgttggac atctgtataa agcgccggaa acgctgacgc
    17041 gtttttatcg gcaaaatgac ccaaccaaca gtatgaaccc cggtatcggc aaaacgagta
    17101 agcggaaatt ctggcaggaa aatacgcccg acgaaacgca ttaacacggt gtggtttacc
    17161 gtgaatgccc ggcggcgcga tgcctgccgg gcctgcggcg acttaatcgt tctgtgcggt
    17221 ttgcgctccg gcgctggcgc tggctgccgc catttgcgcg gctttttgct ttttatagct
    17281 cagcgcggca gccggaacgg gcatgacttt accggtttca atccatgtac gcaggcgact
    17341 ggcgtccgca aagtgggtat atttgccgaa cgcgtccatg accaccagcg cgaccggttt
    17401 gttattgatc acggtacgca tcaccaggca atgccccgcc gcattggtaa agccggtttt
    17461 cgttaactgg atattccagt tatcacggta gaccaaatgg ttggtattgc gaaacggcag
    17521 cgtatacgcc ggatgcgaga atgtcgccat atcttcgcgc gtggtgctta gctggccaat
    17581 cagcgggtat tgcttcgtgg caatcagcaa ttttgttaaa tcccgcgcgg tcgagacgtt
    17641 atgaatcgac agccccgtcg gctcaacaaa gcgggtatgc gtcatgccca gcgctttcgc
    17701 cttcgcattc atcgctttaa taaatgcgtt ataaccgccg ggataatagt gcgccaggct
    17761 tgccgccgca cggttttcgg atgacatcaa cgccagcagc aacatatttt tgcggctaat
    17821 ttcgctgttc aggcgcacgc gggagtaaac ccctttcatt tccggcgtct ggctgatatc
    17881 gaccttcagt atttcatcca gcggcaatcg cgcgtcgagc acgaccatcg ctgtcattaa
    17941 tttggttatc gaggcaatcg gacgcaccag atccgggtgg ttcgaataga tcactttatt
    18001 ggtgttgaga tcaacaatca ttgcgctacc ggaggcaatc tcaggttgag acgccgcggt
    18061 tgtcgctgcc gttttcgcca cagcctgcgg ggcaaaagga acggccaaca tcagagcaag
    18121 gctcaggaat gaagctcaga atttcagcat gatgagattt ctgataatga ttcacgcgcg
    18181 tcgtaacgca caccgcctga gctaagatta tactcaagct agcagtggca tcatagcggc
    18241 acgccagcgt tgccgctaca gaagaatcgt cagcaaatgc tgcattgctg gcttttgcgc
    18301 cagccctttt tcgcatcaga acaggcggta gtcatatccc cacaggatca cggtgatcgc
    18361 cagcagcacc tccaggacca gtacgccgat agcgagcgtc gaactggaga agcttaatcc
    18421 ctcctctcta ttaatgttaa ggaaagtcgg aatacccaaa tacagcaaat agccggtgta
    18481 aaaaagcgcg acagcgccga ccaaagcgca tagccatacc aggggataga gcgccaccag
    18541 accacttaaa aacagcggcg tcgcgacata gccggcaaaa accatacagc gcgcaagcga
    18601 tggccgttgc ggatagtttc gcgccatcca ccagatgacg cgtcccatca ccgcgacgcc
    18661 cgccagcatc acgccgtaga acaagaccgc cagcgcaaaa gcggtaaaca gcgagagttg
    18721 taacacgttg ccgtcgccaa aattccagcc gatttgcgtc gtgccgataa aggcgcagac
    18781 gacgggaatc gccgccatca gcaaaacatg gtgcgtatag tgatgcgaaa cggtttcgtt
    18841 ttcgcttttg atcacctgca tttcccgatc gggatgggaa aaaagccccc atacatggtt
    18901 catactgccc ccttctgctg cctcagatgc cagtatgttc aagtataatt cagtttctgg
    18961 ttattttatg agcaatggca aaatagtctc cggcaaaacg tcggctttgc cgcgcacgcc
    19021 tcttgccagg gtgtatgctt aatgccggag gtggtttacg catggatatc aacacgctta
    19081 ttacgcatta tggctatgcg gcgctggtta tcggcagtat ggccgaaggt gaaaccgtta
    19141 ccctgttggg gggcgtcgcg gcgcatcagg gattactcaa gtttccgctg gtggcggcgg
    19201 ccgtcgcgct gggagggatg atgggcgatc agctacttta cctgttagga cgatgctatg
    19261 gcgggaagat cctgcgtcgt ttcccgcgtt atcatacgaa gattcgtcgc gcgcagaaaa
    19321 tgatccaacg ccatccgtat ctgtttgtga tcggcacgcg ttttatgtat ggcttccggg
    19381 tggttggccc gctgctgatt ggcgccagcc gcctgccgcc taaaattttt ctgccgctga
    19441 atattgtagg cgcgctgatc tgggcgctgc tgtttaccac gctgggatat cttggcggcg
    19501 aggtgatcgc gccatggctg cacgacctcg atcagcatct caggcacgga gtctggctga
    19561 ttctggccat cgtcctggtg gtgggcgtgc gctggtggct gaaaagacgc ggcaaagcgg
    19621 aggcccgtta aacccgatgg tatccggatg gcataacgcc gccatccggc cccggcgttt
    19681 attttgcgtt gaattgcgga ttcaccagca taaatccgcc gtcgacaatc agcgactgac
    19741 cggtggtata gcttgcgcct tccgaacaca gccaggcgac gaggctggct atttcatgcg
    19801 tagaacccgg tcgggcgata gggatcgagg gttccgatcc cggctcaatg tcgctgtcat
    19861 ccatatcatt catcggcgtg gcgatagcgc ctggcgcgac ggcgttgacc aaaatatgat
    19921 gctcaatcag ttccagcgcc atggatttag tcaatccccc caacgcatgt ttcgccgcgg
    19981 tataggcgct ggcttgcgga agcggcgtat gctcatggac ggaggtgatg ttgataatgc
    20041 gccctccctc tccttgttta atcatatgcc gggcggcgat ctgcgcgcag agaaacgcgc
    20101 catcgacatc cacggtaaaa atttgccgcc actgcgtaaa cggcatatca ataaacgcgg
    20161 atttggtcat cgccccggca ttattgacca gcacgtcaac gcgccccagg cgctggataa
    20221 gatgttcaat ggcctgcgcg ccctcgggta actggctcag gtcaagatga atggtctctg
    20281 cccgcacacc aaactgcgcc gcttttttcg ccgtctcctg cgcgccgcgt tcatcggaat
    20341 gccaggtgat accaatatca aaaccgtttt gtgctaataa caacgcacac gctttgccaa
    20401 ttcccgaatc tgatgccgtt acaattgcga ctttggtcat attcctctcc ggatgaatca
    20461 tacacagcct aagtatagga accctgtctg aatcatctgg aaaaatcagg aatgataacc
    20521 gccgcccagc gcgctggtaa gctgaataga ggcatccagc cactggccct gcaacagcaa
    20581 gccgttacac tgctcgcgca gtgccgggat tttggcctcg ctcacgcggg aacccgcaat
    20641 aatgccggca ttaaagcgcg cttgcgccag accgaccaca cgctgcgcgt catgctcaat
    20701 ctgctgctga tgctgatttt tctgcgccag cgtctctacc tgactggcgg cgcgcgccac
    20761 atcattaacc gcatctacca ccgctttgtt gtagttggcg atagaaaggt tgctttgcgc
    20821 tttggcgata tcgaggttgg cattcagcct gccgctgtcg aaaatcggca gcgtcagccc
    20881 gccggtaatg ccatattgct gtgcggaatg gcggaacaga tcgctcagat gtaacgcatc
    20941 ctgctgtaaa aaagccatca gattgatatc gggataaaac gcggccttcg cggcgtcaat
    21001 gctgctcaac gaggattcaa tgtaccagtg cgcggcctgt agatccgccc ggcgcgccag
    21061 caacgaatac cccagttgcg acggtaactg gctttcaacg gcggggagac tcacctgacg
    21121 cagcttgagc gccgccgatt gcgtattggt taacgcgctg agccgcgctt caataacctt
    21181 cattttaccg ttaacgtcat tcaactgctg ctgggttttg ctggcgtcga tatcggtctc
    21241 gaccccttca acagaagaag taataccgtg ttgatacagc tcccggttta ccgccaccac
    21301 gttttgctgc tcatgctcga tttgcatcag cacatttttc agcgccgcct gcgtctgcca
    21361 ctcccagtag agtcgcgcca cgccgcttgc cagcaattgt cgggtctgct cctgctccgc
    21421 ttcgcgcgct ttgaccgccc cgatccgcgc ggtaacttca gcgcggtttt tcccccataa
    21481 atccagatcc cagcccgccg tcaggccgaa tgtaccgttg gtataccacg gcccggtcgt
    21541 tcccgccgcg gggtcggtaa tcgcgaatgg ccccatcagc ccttccgcgg acattcgctg
    21601 gcgctcaatg tcggcagaaa agtcgagctg cgggccgtcc tgcgcctcaa ccgctttcgc
    21661 ctgcgcttcc gccagttgaa tacgctgttc agccacctgc atatccggcg aatgctgtat
    21721 ggcattatca atcagcgcgt caagctgcgc atcgtgatac gccttccacc actggctatc
    21781 cggccaaccg tttttcaatg ccgccggcag gctggaatca acatgagaag agggcgtctg
    21841 ctgggtcagc gactggcggg tatcgtgcat aggggcgcag cccgccagca aaataaaaag
    21901 cggtaagctc gctgtcgcgg caaggaaaga attacgattc atggaggtgt tctgataaaa
    21961 aaaggtgcgc agagagtacg tcttacggcg aactattttt tagttacgcg tggcaataca
    22021 tcatcagaca acaaaagaca tattttgaaa tttatatgat tagcaaataa tttcatctga
    22081 tacatttttt gatgtaatac ttcaatgaaa agtcccacta acccgttcat aaatgaacga
    22141 ttttgctgca atacgcgcca gcagctttca tgagttaaac gtcgccgcgc ccaacaaagc
    22201 agcagatggc ttaatacttt cctatacttt gtttgtattt accaataaag ggacaaacaa
    22261 tgaaaattct tctatgggca atcttaatta tttttctgat tgggctgttg gtggtaacgg
    22321 gcgtgtttaa gatgattttc tgattcctgc gccgggcagc gatagtatct gcccggcaca
    22381 cgttctggac gctgtagaga ttagatttta atagcctgaa tcacccgcgc aatctcggac
    22441 gaacggttta acgcccgaat cgactgaaag agttctgtcg cctcaatata ttccttacgt
    22501 aaatatccca accactgttt aatacgcgcg acatggtata aaccggtatc gccctgcttt
    22561 tccagtcggg tatatttttg taataacgtt accacttccg gccacggcat acgcggttcg
    22621 ttatacttca ccacccggct caggttagga atatttaacg ccccgcggcc aatcatcacc
    22681 gcatcgcagc cgctggtcgc catacatgcc tgcgcgctct gccagtccca gatttcgcca
    22741 ttagcgataa ccggaatagt cagacgctgg cgtatttcgc cgatcgcctg ccagtcgata
    22801 tgctcggcgc ggtagccctg cgctttggta cggccatgca ccaccagttc actggcgccg
    22861 gcctgctgca ccgcatcggc gatttcaaat tttctatcgc cgctatccca gccgagacgc
    22921 acttttaccg tcaccggcag atgcgacggt accgcggccc gcatcgcttt cgcgccctga
    22981 tagatgagtt cgggatctgt gagcaatgtc gcgccgccgc cgctgccgtt caccactttt
    23041 gacggacagc cgcagttcag gtccacgcca tacgatccca acgccgtcgc ccgcgcggcg
    23101 ttttccgcca gccactgcgg atgctggccc agaagctgaa tacgcaccgg cgtgccggac
    23161 ggcgtgcggc tggcgtgaag caactccggg cagatgcgat gaaacacttt taccggcagc
    23221 agctgatcca ccacgcgcac aaattcggtg atgcagagat cgtaatcatt cacttcggtc
    23281 agcagctcgc gcactaacgc gtcgagcacg ccttccatcg gcgccagtaa aacacgcata
    23341 tcggtatcca cagcaaaaaa agaggcgcta tcataacgcc tctctgcgat gagcaaaact
    23401 ttttgccggg tggcggcgca aacgccacgc tacgtcacgt aaggcgctca acgcggctca
    23461 agacagttat cttctttcca gccgtacagc cattcgatac cgcgataaaa cgcctcctgc
    23521 gatttccctt tccacagcag attacgcacc tgacgctcca ccccggcggc gtgatagaga
    23581 cgccccatct cgcgggtaga ccagacgata cgcgccgtgc ggggaatacg caccgactca
    23641 tacagcgcaa atgcctgctg cgcgtcgccg tcgcagcgtt ccagcgcttt gcctagcgtg
    23701 acggcgtctt ccagcgccat acaggcgccc tgggccatat attgcgccac cggatgcgcg
    23761 gcgtcgccca ccagagtgat acgctcggtt ccccattttg cgaccggctc gcgatcggcg
    23821 gtcgaccagc ggcgccagga ggtcggctta tccagcatct gacgcgggcg gggatgaata
    23881 ccggcaaaat aagagagcac ctcttcttta ctgccgtctt tcacgcccca ctcttcttgc
    23941 tggcggctgt ggaatgtcac caccagattg tactgttggc ctccgcgcag cggataatgg
    24001 accaggtgac aatgcgggcc tgcccacagc accggtgcgt taatacgtaa atcgtccggc
    24061 atatcgtcgc aatcaatcac cgcccgatag actacatgcc ccgttacgcg cggcgcgtcg
    24121 ccgagtaaac tttgccgcac gaccgattta acgccgtcgc agcccacgag aatatccgcc
    24181 gtccagctat ttccctgctc atcaaacacc gtaacgtcat ccggcgtctg gcggatatcg
    24241 acaatatggg tcgaggtacg atactccacg ccagggtgcg tcagcaccgc ttcccatacc
    24301 gttgcatgaa tatctacccg gtgaattacc gcatacggcc cgccaaaatg gtcgcggaac
    24361 gcctgcccgg tttcaatgcg taccacttct tcggcattca cggcatccat catggtaatg
    24421 tgatcggtaa acaccgcacg ctggcgggca acatcgccca caccgagact atccagcgcc
    24481 gaaaaagcgt tcggcccaag ctgaataccc gcgccaatct cgccaatttc gtgcgctttt
    24541 tccagcagca tgacttttat tccctggcgc gccagcgaca gcgcggtcgc cgcgccgccg
    24601 attccgccac ctacaataat tgcgcttgtc acgtgagtca tggtcattct ccttttcagg
    24661 ccgggatttt atcttgttga ttttccggcg cggcggcaat aaacgccggt agctgtacgc
    24721 aggcgtcata aacggcttta cagcgcggat agcctgataa atcgcagccc atcctgagcg
    24781 cattcgccca ctgaggaatc aggcagcagt ccgcaaggcc tggcgcgtcg cccacgcaga
    24841 atcgtccgga ctgactttta cgcaatagct gctctaccgc gcttaaccct tgctgtatcc
    24901 agtgggcgta ccagcgtttt ttatcctctt cgctaacctt cagctcatcg gtcaggtagc
    24961 gcaacacgcg catgttattg atcgggtgta tatcgcaggc gatagcgtag acaatttcca
    25021 gcgcctggct gcgcgccggg tcgctcgtcg gcagcagcgg cgtttgcgga aaatgtcggt
    25081 ccagccagtc gacgatggcc agcgattgcc ccaacgattc gccgtcatca gtgactagcg
    25141 tcggcaccag gcctaccgga ttcatccgtc ggtaggccag cgcattctgc tggccgatac
    25201 gaatattgac gcccactgtc tggtaatcaa tcccctttaa cgccagcgca atacgtacac
    25261 gataagacgc cgaactatta aagaaactgt acagcttcat cgttcacctc agacaatttt
    25321 cacagcaatc ggcgtcagac cttctacgtt cccggtgatg acatcccctt tcaccactgc
    25381 gcccaccccc tctggcgtac cggtgaaaat caaatcgcct ggctgcaatt caaaaaagcc
    25441 ggacaaatag ctgatggttt cattcaccga ccaaatcaga tgacgaatat cgctgcgctg
    25501 atggtcttcg ccgttaacct gtagccaaat aggggcgtta tccacattat gcgtttcagc
    25561 ggctttgtgt aatggcgcaa tgggcgcgga gagatcgaac gctttgccaa tttcccacgg
    25621 gcgtcccatc tgacgcattt ccatctgacg atcgcgacgc gtcatgtcca gaccggtggc
    25681 gtatccccag acatattcat gggctttttc tagcgggata tcgctcccct ttttaccaat
    25741 cgccaccacc agctcaattt cataatggta gttatcggtc tgcgccggat acggcagttc
    25801 cagggtatcc cccgccgcta ccgggacgac agcgtccgct ggtttacaaa agaagaacgg
    25861 cggttcgcga tcgggatcaa aacccatttc acgggcatgg gcggcatagt tgcgacccac
    25921 gcagtaaacg cgacgtaccg gaaactgctc atcactgccc gccacgggta ctgtcaccgg
    25981 ggcctgcggc tggaatacat atttggtcat gttctctctc cctaattaat aacgtgcttc
    26041 gcggaacagc cccagggctt cctgaaccgg cttgtccgaa aagctgaata acaccgtgtc
    26101 ttcgctgctg cgaaacgaca cctcatgcca ggtcggcgcc acaaaaatgt cttttgcgga
    26161 aaaatgaaaa gtttcgttgc cgatagtgac ctgccctgcc ccttcaacga cgtggtagat
    26221 agtgctgtcg gtgctccgcg ccacacgcga ggcaaagcct tttggcagca gttgcaggaa
    26281 cgcgcccatc gacggcatcg gataaccgcc agtgacggga ttaacgtaac gcagcttgta
    26341 gccttcccac tcatccggat cgcccatacg ggtcagatcg tgcaacgcct cgcgactgcg
    26401 gtcgtaacgg tagttgaaaa tcggcgacga gttcccgcgc tggtggcgca gcggcagcat
    26461 attcgctgca tagcgcggca gataatcgcc ctcttttcgc gtcaccggct gctgatcttc
    26521 gggatagtct tccgcaaaac cacagcccag gagattgact aacggcagat ccagaccatc
    26581 cagccatacc accggctctg atcccggatt accatgatcg tgccagcgcc actgcggcgt
    26641 caggataaaa tcgccggtat gcattggcgt gcgctcgccg tccaccgcgg taaatgcgcc
    26701 tttaccttcg acgataaaac gcagcgccga ctggttatgg cgatgactcg gcgcgacttc
    26761 gccgggcagg atcagctgta aaccagcgta taaggtcgcc gtgatcgacg actgaccgcg
    26821 caatgccgga ttttccagca ccagcacccg gcggatcgcc tctttcgcgc caatgacatt
    26881 gccgctttcc atcagtagcg gacgaatttc ctgataattc cagtaggccg gcgcgcagtt
    26941 ggcgtttggc gtctgcggta ccaggtgatg taacgattcc cacagcggcg tcagattctg
    27001 cccggaaata tgctggtaat actgctgacg gctatctttt acgttctgat ttatttcaga
    27061 catggagatt ctccttattc gtttacgacg ctggcacgcg gcaggtcgtc aggtacagaa
    27121 atcgaaaggc ggacaaccac tgtcagcagg gtaagcatta ccgcgctgat agccgccgga
    27181 atagcaatga caaaaaacaa cgtatcgaaa gagaaattga gggccatcat catgccgccg
    27241 gagagcgaac cgacaatcgc cccgcagcgt ccaatggcgt tcgaccagct cacgcccgtc
    27301 gcccggcttt gggtggggta cagcgtcgcc gtcagagcat tcagcccgac ctgggaaccg
    27361 ctaataccga tgccggtacc aaaaatcgcc agcgccatca gccaaaggcc gttttcgctc
    27421 aggcctatca tgacaatgca aactgcgccc agcgcatagc tcaccgccag tacccggaac
    27481 gggttaagcc ggtccatcaa cacgccgagt aacagcgcgc caagcgtgcc gcccacctgg
    27541 aatgcggcag tcacccacga cgcctgttgc agatcaatac ctcgatggtt aagtaacgtc
    27601 ggcatccagc tggaaagcag atagataatg agcaggctca taaagaacac cacccataac
    27661 atcagggtaa tgacaagctg tcgcccggca aaaagctggc gaatactgcc tttggcgacg
    27721 gctgccgtct catgcagaaa gaattgcgta tcgtgatagc gctcgccggt aatggcgctg
    27781 accgtccggg cgacaacggc ttgcggtagt tggcgacgta cctgccagcg gggagattcc
    27841 ggcagcgcga acagcaggcc gaaaaacagc atcaaaggca agatgccgcc tagcgccaga
    27901 attccgtgcc agccaatcag cggcaccagt tgcgcgctca caatcccgcc catcgccgac
    27961 cccagggtaa aaccgcagaa catcagcgtg accagcgctc cgcgtcgacg agcgggaagg
    28021 tattccgacg tcatggtgat ggtattcggc atcgctccgc ccagtcccag accggttaag
    28081 aagcgcagca acaccagggt ttctatatcc ggcgagaaag cggaaagcag gctcaatgcg
    28141 ccgaatagcg ccacgcaaag ctcaatgacc cgcttgcggc caaagcgatc cgccagcggc
    28201 ccgcatagca gcgcgccggc cgtaagcccc agcagccctg cgccaaacag cggcgcaagt
    28261 tcgctggcgc ttagctgcca gtgagtacga atatccgggg cgatgaagcc aatcgcggcg
    28321 gtgtcgaaac cgtcgagcat aaccaccaga aaacagcaga tgataacgcg ccactgcatt
    28381 ttgccgacgg gcgcggcatc aataagggct tgtagatcac gtcgttgagt catagctaat
    28441 gcctcagtgc agggagatag atgttgtttt tatgtttgct atgttacgag tttgtagagt
    28501 gagcgataaa atgtacaatg gcttttcagg cagagacata acctggaggt tatagcgaat
    28561 ggcgaactgg gcgcagaaat tgaaattaca tcacctgcaa acgctggttg cgctgggcga
    28621 acagggcaac ctgacgcacg tcgcccggat gatgaatatc tcccagccgg cgctatcgaa
    28681 gtggctatct caactcgaag atgagatagg catcacgctt tttgagcgcc acagtaaagg
    28741 actacgcccc tcggaaggcg gtaaattact gctccagcac gcccagcgcc taattaacga
    28801 tctggagcgt tcacagtatg aaatcgcccg tttcaagcag ggcggcctgg ttggcagcct
    28861 gaagatcggc tgttcgcccg tggcgactga ctgcgtatca caggcgattc tgagcctgct
    28921 taacgaaatg ccgacgctgc atctgaatat tgaagagaag gtaatgacgc cgctgctgca
    28981 cgatttgctt gccggtcagg tggatgtggt ggtagggcgt gtcggcggcc gcgccctgca
    29041 actgccgctt aattatcagg tactttatac cgagccggtc tgctttgtgg cgcgtccgca
    29101 ccatccgctg gccgcgcgag cgcagatcgc ctggagcgat ctggcacact ggcggtggat
    29161 agtctggcca accggcaccc ctattcgcat cagtattgat aacgccctcg tcgataatgg
    29221 cgtcatgctc ccggaaaaca ccattgaatc ggcgtcaatg aacgtcagca ccaatttgct
    29281 gcaaagcagc gatatgatct ctattctttc tttacggctg gcgcaacgct atgccagcca
    29341 ggggcaactg gcgattttaa acttgccaaa aattgagcaa aaaggcagcg tagggatgtt
    29401 ctggcgtaag aatgagacgc cgtctttggc cctgagtcgc tttttgtatt ttttagccca
    29461 ggtttaacgc cgccgaccag gggcattgcc cgatgttcct gctgtctata cccactatgc
    29521 taagaattca tgatgtgatc ggtagcacgt tttaacgttt aattgtatga tgaatccatc
    29581 tcatcaaggg ctttaaacat gagtaagtca ctgaatatta tctggcaata tatacgcgct
    29641 tttgtattga tttatgcctg tttgtacgca ggcatttttc ttgcatcact gcttcctatc
    29701 actattcccg gcagcattat cgggatgtta attctgtttg tattgctggc gctgcaaatt
    29761 ctgccggcaa agtgggttaa ccccggctgt tatgtgctga ttcgttatat ggcgttgctg
    29821 tttgtgccaa ttggcgttgg ggtcatgcaa tattttgact tactgcgcgc gcaattcggc
    29881 ccggtggtgg tctcttgcgc tatcagtacg ctggtcgttt ttgtggtcgt aagctggagt
    29941 tcacatctga tacacggtga gcgtaaagtg gttgggcaga agggaacgaa aaaatgatga
    30001 catatatctg gtggtcgtta ccgctgacgc tggcggtatt tttcgccgcc cgcagactgg
    30061 cggcgcattt taaaatgccg ttgctgaatc cgctgctggt ggcaatggta gtcattattc
    30121 cttttctgtt gctgaccggt attccctacg agcactactt caaaggcagc gaagtactta
    30181 acgatctgct gcaaccggcg gtggtggcgc tggcctatcc cctttatgaa cagttgcacc
    30241 agattcgcgc gcgttggaaa tccattatta gcatctgttt tgtcggcagt ctggtagcga
    30301 tgattaccgg aacatccgtt gccttgctga tgggcgcaac gcctgaaatc gcggcatcgg
    30361 tactgcctaa atccgtgact acgcctatcg cgatggcggt gggcggcagc atcggcggca
    30421 tccccgcgat cagcgcggta tgcgtaattt ttgtcggtat tctgggcgcg gtgtttggcc
    30481 acacgctgtt aaacgcgatg cacatccgta ctaaagccgc acgcgggctg gcaatgggga
    30541 ccgcctcaca tgcgctcggt actgcgcgct gcgccgagct ggattaccag gaaggcgcgt
    30601 ttagctccct ggcgctggtg atctgcggca ttattacctc gctggtagcg ccctttttgt
    30661 ttccgctcat tctggcggta atgcgctaac gacgggacaa aagaccgggt taaaatttgc
    30721 gatacgtcgc gtatttttca tttaagtttc acaagttgca taagcaatga gatttagatc
    30781 acatattaag acatggcagg cccgtaaact acggttccat tacattgtta tgaggcaacg
    30841 ccatgcatcc acgttttcaa actgcttttg cccagcttgc ggataatttg caatcagcgc
    30901 tggcccctat cctggcggac caccattttc ccgccatgct gaccgcagag caggtctcga
    30961 cgcttaaaaa tacggcggga ctggacgaag acgcgctggc tttcgcactg ttacctctgg
    31021 cggcggcctg cgcccgtacc gatttgtccc attttaacgt cggcgcgatt gcgcgcggcg
    31081 ttagcggcaa ctggtatttc ggcgcgaata tggagttcct gggcgccacc atgcaacaaa
    31141 ctgtgcatgc tgaacaaagc gcgattagcc acgcctggct acgcggcgaa aaagggctcg
    31201 ccgccgtcac cgttaactac acgccttgcg gccactgtcg ccagtttatg aacgagctga
    31261 acagcggtct ggatctgcgc attcatctgc cgggccgcgc gccgcatacg ttacgcgatt
    31321 atctgcctga cgctttcggg ccaaaagatc tggagatcaa aacgctgctg atggacgagc
    31381 aggatcatgg ctttacgtta acgggcaata cgctaacgca agcggcgatt acggcagcca
    31441 ataagagcca tatgccttat agccactcac cgagcggcgt ggcgctggaa tgtaaagatg
    31501 gccgtatttt caccggcagc tatgcggaaa acgccgcctt taaccctacg cttcccccac
    31561 tgcaaggcgc gctaaacctg ctgagtctca atggctatga ctatgcggat attcagcgcg
    31621 cgattctggc ggaaaaaggc gatgcggcat taattcaatg ggatgccacc gccgcaacgc
    31681 tgaaagcgtt aggttgccat aatattgacc gcgtgcttct cggctaagca aatgtgccgg
    31741 atagcgacgc actggcgtct tatccggcct gactctcctc tcccgcgacc cgatacaagg
    31801 gaaatcatgc tgaaaatctc cgcaatcaga cggcggtttc ttgcgctacg tcttcgggta
    31861 cagtagcctg atcgtacttt catcctggta tcgagtttcc tgcatgttaa agcgcgtgtt
    31921 ttacagcctg ttggtcctgg taggcttgct gctgttgacg gtgcttggcc tcgatcggtg
    31981 gatgagctgg aaaacagcgc cctatatcta tgacgagcta caggatctcc cctaccgcca
    32041 ggttggcgtc gtgttaggga cagccaaata ctatcgcaag ggtgtcatta atcagtacta
    32101 tcgttatcgt atccagggcg cgttaaacgc ttacaatagc ggtaaagtca attacctgct
    32161 gctcagcggc gacaatgccc tgcaaagcta taacgaaccg atgaccatgc gcaaagacct
    32221 tatcgcggcg ggcgtcgatc ctgcggacat tgtgcttgat tacgctggct tccgtacgct
    32281 tgactccatt gtgcgtaccc gcaaagtgtt tgatatcaac gactttatta tcatcactca
    32341 gcgcttccac tgcgaacgcg ccttgtttat tgcgttgcat atgggcattc aggcgcagtg
    32401 ttacgcggta ccttcaccca aaaatatgct gacagtacgc ttgcgcgaat ttggcgcccg
    32461 ctttagcgcg ctggcggatc tctatatttt taaacgcgaa ccgcgttttt taggcccgct
    32521 ggtacctatt cccacgcagc atcaggtgcc aaatgacgcc caggggtatc cggccgttac
    32581 gccggaacaa ttgcttgaac tggaaaagaa aaaagggaaa tgatcatgga tgtacagacg
    32641 atatttgtca tattagcctt tctgctactc ccgctttttt gctttcgtga ggcctggaaa
    32701 ggctggcgaa ccggcgcggt agataaagtt gtcaaaaatg cgcgaaaacc ggtttatgtt
    32761 tatcgcc
//
LOCUS       DAJVKX010000040        32268 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000040 DAJVKX010000000
VERSION     DAJVKX010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 32268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32268
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.040"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(111..1871)
                     /locus_tag="OPY25_001905"
     CDS             complement(111..1871)
                     /locus_tag="OPY25_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     accessory protein YcaO"
                     /protein_id="HCS0927532.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLLDLGFHIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFSLTENDDVPEGLLDARLRAFYDPENELTGSQLIDLQSGNEERGVCGLPFTR
                     QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPAEVMARYPAVMESIATLEAEGFPIFAYDGSLGGKYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFTDWSFSGTTEEEFATLMAIFAAEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNNMGSHLREILLSLPGSAWNKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGADNGWYTLRVGELKAMLALAGGDLEQALIWTEWTMEFNSSVFSPVRANYYRCLQ
                     TLLLLSQEDARQPLQYLNAFIKMYGAEAVEAASTALSGEAAFYGLPAVDHDLQAFPAH
                     QSLLKAYDKLQRAKAAYWSK"
     gene            2008..2700
                     /locus_tag="OPY25_001906"
     CDS             2008..2700
                     /locus_tag="OPY25_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCS0927533.1"
                     /translation="MKAFDLQRMALDNVSVAFLGEVALRSFYTFVLVFLFLKVTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMLPVLVVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKSVVIVEDGELAWEKLQRSNMTEFEFFMELRLNGVEQLGQVRLAILETNGQIS
                     VYFFENKDVKPGLSILPEHCTPRFIVAPEAGDYACVRCSEVIRMNVGEKQLCPRCANP
                     EWTKASRAKRVV"
     gene            2886..3974
                     /gene="serC"
                     /locus_tag="OPY25_001907"
     CDS             2886..3974
                     /gene="serC"
                     /locus_tag="OPY25_001907"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HCS0927534.1"
                     /translation="MAQVFNFSSGPAMLPAEVLKLAQQELRDWHGLGTSVMEISHRGK
                     EFIQVAEEAEQDFRDLLNIPSNYKVLFCHGGGRGQFAGVPLNLLGDKTTADYVDAGYW
                     AASAIKEAKKYCAPQIIDAKITVDGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAID
                     ETPDFGPEVVVTADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKA
                     HESCPSILDYTVLNDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELL
                     YGVIDNSDFYRNDVAQANRSRMNVPFQLADNALDKVFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPIEGVKALTDFMIDFERRHG"
     gene            4045..5328
                     /gene="aroA"
                     /locus_tag="OPY25_001908"
     CDS             4045..5328
                     /gene="aroA"
                     /locus_tag="OPY25_001908"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCS0927535.1"
                     /translation="MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNL
                     LDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGPLRASGTLELFLGNAGTAMRPL
                     AAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGG
                     DIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANH
                     HYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRF
                     ADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA"
     gene            5471..6232
                     /locus_tag="OPY25_001909"
     CDS             5471..6232
                     /locus_tag="OPY25_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HCS0927536.1"
                     /translation="MKNKSLLLAVAISATLLAGCKNGVNGNLIASSGMSAYKAATLSD
                     ADVKALSNNACKQMDSENQLAGSKSKYTKRLSKIAKALGNNIDGTPVSYKVYMTSDIN
                     AWAMANGCVRVYSGLMDLMTDNEIEGVLGHELGHVSLGHSRKAMQTAYATLAARDAIS
                     ATSGVAAQLSQSQLGDLAEGVINLAFSRSQESDADDFSYNLLKKRGINTQGLVTAFDK
                     FAIMDAGHAKSLMDSHPASADRAQHMRDRIAEDKK"
     gene            6405..7088
                     /gene="cmk"
                     /locus_tag="OPY25_001910"
     CDS             6405..7088
                     /gene="cmk"
                     /locus_tag="OPY25_001910"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCS0927537.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDLASEDALVPLASHLDVRFVSTDGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQENGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTRLSIEQVIEKALQ
                     YARQKLALA"
     gene            7202..8875
                     /gene="rpsA"
                     /locus_tag="OPY25_001911"
     CDS             7202..8875
                     /gene="rpsA"
                     /locus_tag="OPY25_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCS0927538.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEINVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKSNPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDDVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            9031..9315
                     /gene="ihfB"
                     /locus_tag="OPY25_001912"
     CDS             9031..9315
                     /gene="ihfB"
                     /locus_tag="OPY25_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HCS0927539.1"
                     /translation="MTKSELIERLATQQSHIPAKAVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            9545..11809
                     /locus_tag="OPY25_001913"
     CDS             9545..11809
                     /locus_tag="OPY25_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HCS0927540.1"
                     /translation="MKITTVSVCVVCGILPLMILPVLPDTWILAVLFCLACLLCLIPH
                     HYARYAALTLLFFMWGIFAARQAIWVGNVLPAATQEATVVITATDHMTTHYGRITHLH
                     GKPLFPAVGIVLHGQYLPTEVCAGQQWAMTLKVRAVHGQLNEGGFDSQRYALAQHQPL
                     TGRFLQAKAINPECSLRGRYLASLRATLAPYPWQQVILALGMGERGAVSQEVKAVMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRGGQFFLPVRWIRWQTPLLGGILCAICYAWLTG
                     LQPPALRTVAALSVWGGLKLSGRQWSGWQVWCCCLAAIIFADPVAVISQSLWLSAFAV
                     AGLLFWYQWFPAPNGNFPRGLRWLLNLLHLQAGITLLLLPLQVALFHGISVTAMLANL
                     FAVPWVTFVTVPLILAGMILHLTGPFFLEEWVWYLTDRALAALFYLLNALPQGWVNID
                     NRWQWLTLLPWLTLIAWRLNVWRTWPAVCLCGLLLMSWPLWRPINASGWQVHMLDVGQ
                     GLAIAIVRGDKVILYDTGRAWPEGDSGQQVIIPWLRWHNLTPEGVILSHEHLDHRGGL
                     RSLQQVWPSMWIRSPLGWQGHLPCFRGEQWQWQGLTFQAHWPLRESADRGNNRSCVVK
                     VDDGVHSILLTGDIEAGAEQKMLSRYWRHLAATFIQVPHHGSNTSSSLPFIQRVHGEA
                     ALASASRYNAWRLPSRKVKQRYRQQAYQWFDTPHQGQISLLFSPQGWRIQGLRDQILP
                     RWYHQWFGVSEDNG"
     gene            11846..13594
                     /gene="msbA"
                     /locus_tag="OPY25_001914"
     CDS             11846..13594
                     /gene="msbA"
                     /locus_tag="OPY25_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HCS0927541.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGIALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLLWMPLVVIGLMILRGITSYISSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVAFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILVVLAPIVSIAIRVVSKRFRSISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNKMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFAILDSEQEKDEGKRV
                     IDRATGDLEFRNVTFTYPGREVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGHILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEEYSREQI
                     EEAARMAYAMDFINKMDNGLDTIIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEQADEIVVVEDGIIVERGTHSELL
                     AQHGVYAQLHKMQFGQ"
     gene            13591..14568
                     /gene="lpxK"
                     /locus_tag="OPY25_001915"
     CDS             13591..14568
                     /gene="lpxK"
                     /locus_tag="OPY25_001915"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HCS0927542.1"
                     /translation="MIARIWSGESPLWRLLLPLSWLYGLVSGAIRLSYKLGLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVIWLVEKLQQRGVRVGVVSRGYGGKAAAYPLLLTPETT
                     TAEAGDEPVLIYQRTGAPVAVAPERAAAVKAILAAHNVQIIITDDGLQHYRLARDIEI
                     VVIDGVRRFGNGWWLPAGPMRERASRLKTVDAAIVNGGVARAGEIPMQLAPGLAVNLR
                     TGARCDVAQLSNIVAMAGIGHPPRFFATLEACGAHPQKCVPLADHQTLAPADVQALVG
                     EGQTLVMTEKDAVKCRAFAEDNWWFLPVDARLSGEQPDKLLEHITSLVR"
     gene            14612..15844
                     /locus_tag="OPY25_001916"
                     /pseudo
     CDS             14612..15844
                     /locus_tag="OPY25_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459961.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YcaQ family DNA glycosylase"
     gene            15896..16078
                     /gene="ycaR"
                     /locus_tag="OPY25_001917"
     CDS             15896..16078
                     /gene="ycaR"
                     /locus_tag="OPY25_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HCS0927543.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEQQELICKLDNLAFPLRDGIPV
                     LLENEARALTSDESKS"
     gene            16075..16821
                     /gene="kdsB"
                     /locus_tag="OPY25_001918"
     CDS             16075..16821
                     /gene="kdsB"
                     /locus_tag="OPY25_001918"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HCS0927544.1"
                     /translation="MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCGFTDDTVIVNVQGDEP
                     MIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAKAVPGTGVDTADDLERVRAEMR"
     gene            17032..17925
                     /locus_tag="OPY25_001919"
     CDS             17032..17925
                     /locus_tag="OPY25_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HCS0927545.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADSALWSLYDSQGNPMPLM
                     ARSFTTPGVAQQLAWKTSMLARSGTVRMPVIYGVLTHEEHPGLDVLLLERLRGVPVEA
                     PARTPERWEQLKDQIVEGLLAWHRQDSRGCVGAVDHTQENIWPSWYRQRVEVLWTTLN
                     QFSNTGLTMQDKRILFRTREYLPSLFEGFNDNCVLVHGNFCLRSMLKDARSDQLLAMV
                     GPGLMLWAPREFELFRLMDNPLAEGLLWHYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFNRTNFDLAAKSLLPWLA"
     gene            complement(17905..18681)
                     /gene="elyC"
                     /locus_tag="OPY25_001920"
     CDS             complement(17905..18681)
                     /gene="elyC"
                     /locus_tag="OPY25_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HCS0927546.1"
                     /translation="MLFTLKKVIGGMLLPLPLMLLIIGIGLALLWFSRFQKTGKVFIS
                     VGWLALLLLSLQPVSDHLLRPIENRYPTWQGPQKVEYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLAEGIRLWRANPGARLIFTGGVAKTNTVSTAEVGARVAQSLGVPRSDIITLD
                     KPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQHAGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRAGYETLGRLWQWLKGISGKPGE"
     gene            18817..19620
                     /gene="cmoM"
                     /locus_tag="OPY25_001921"
     CDS             18817..19620
                     /gene="cmoM"
                     /locus_tag="OPY25_001921"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HCS0927547.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLEEIGGR
                     KLRVLDAGGGEGQTAIKMAERGHQVTLCDLSGEMIARARQAAEAKGVSKDMHFIQCPA
                     QDVASHLESPVDLILFHAVLEWVADPVGVLETLWSVLRPGGALSLMFYNANGLLMHNM
                     VAGNFDYVQAGMPKRKKRTLSPDYPRDPAQVYQWLEAIGWQITGKTGVRVFHDYLREK
                     HQQRDCYETLVELETRYCRQEPYISLGRYIHVTAIKSPALAADARITYE"
     gene            19613..20935
                     /gene="mukF"
                     /locus_tag="OPY25_001922"
     CDS             19613..20935
                     /gene="mukF"
                     /locus_tag="OPY25_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HCS0927548.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRIFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALR
                     DDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            20916..21620
                     /gene="mukE"
                     /locus_tag="OPY25_001923"
     CDS             20916..21620
                     /gene="mukE"
                     /locus_tag="OPY25_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HCS0927549.1"
                     /translation="MSLTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEESQPDSGEEE"
     gene            21620..26086
                     /gene="mukB"
                     /locus_tag="OPY25_001924"
     CDS             21620..26086
                     /gene="mukB"
                     /locus_tag="OPY25_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HCS0927550.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMR
                     HANERRVHLDQALAFRRELYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLEELQIRFEEQNEVVAEAAEMQDENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAISALARAKELCHLPDLTPESAAEWLDTFQAK
                     EQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARI
                     ASLSESVSSASEQRMALRQEQEQLQSRIQHLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHE
                     SDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQ
                     YGNQLAKLEPMVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSY
                     SDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADEL
                     RSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQAEDTPSEAS"
     gene            26431..28278
                     /gene="ldtD"
                     /locus_tag="OPY25_001925"
     CDS             26431..28278
                     /gene="ldtD"
                     /locus_tag="OPY25_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HCS0927551.1"
                     /translation="MLLNKMCGRCLSAISLCLAVTFAPLFNAQADEPEMIPGDSAVAA
                     TGQAGPQKQSAATAILAGIQPLPEGVSAEKVRADLQSQLPSGYTPVYMSQLTLLYAAR
                     DMKPMWDNRDAVKAFQQQLAEVAIAGFQPQFTAWVALLTAPAVNGMARDVVLSDAMMG
                     YLHFIANIPVKGQRWLYSNKPYALATPPVSVINQWQIALEEGQLPMFVASLAPQHPQY
                     APMHDALLKLVADSRPWPQLTNTATLRPGQWSNDVPALREILQRTGMLDGGPKIALPG
                     DNTSDSAVVSPSAVVDETSVAQPVDEPTARRSKPAPAARAYDRELVEAVKRFQAWQGL
                     GADGVIGPATRNWLNMTPAQRAGVLALNIQRLRLLPAELSTGIMVNIPAYSLVYYQNG
                     NQVLASRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVWNDPGYLERH
                     GYTVMRGWNSKEAIDPWQVDWATITPSNLPFRFQQAPGAHNSLGRYKFNMPSSDAIYL
                     HDTPNHNLFQRDARALSSGCVRVNKASELANMLLQDAGWNDARISGALKQGDTRYVNI
                     RQNIPVNLYYLTAFVGADGRMQYRTDIYNYDLTARSSAQIVPKVEQLIR"
     gene            28538..29086
                     /locus_tag="OPY25_001926"
     CDS             28538..29086
                     /locus_tag="OPY25_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HCS0927552.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPSPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRAYIQDELAKLNHFFRDYRANKVRSIDPRLFDQLYRLQGLLGTR
                     KPVQLISGYRSLDTNNELRARSSGVAKKSYHTKGQAMDFHIEGVALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            29114..29761
                     /locus_tag="OPY25_001927"
     CDS             29114..29761
                     /locus_tag="OPY25_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCS0927553.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDA
                     SGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPEKEDEFWLQGLPAQSRMFGLDEC
                     QPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
                     SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNSFLQDEMPVW"
     gene            complement(29823..31013)
                     /gene="aspC"
                     /locus_tag="OPY25_001928"
     CDS             complement(29823..31013)
                     /gene="aspC"
                     /locus_tag="OPY25_001928"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HCS0927554.1"
                     /translation="MFENITAAPADPILGLADLFRADDRPGKINLGIGIYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFARCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRIAADFLAKNTPVKRVWVSNPSWPNHKSVFNAAGLEVREYAYYDAENHSLDFE
                     ALQASLSEAQAGDVVLFHGCCHNPTGIDPTLEQWQVLAELSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAALHKELIVASSYSKNFGLYNERVGACTLVAADAETVDRAFSQMK
                     SAIRANYSNPPAHGASIVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKDQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(31198..32262)
                     /gene="ompF"
                     /locus_tag="OPY25_001929"
     CDS             complement(31198..32262)
                     /gene="ompF"
                     /locus_tag="OPY25_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HCS0927555.1"
                     /translation="MIPALLAAATANAAEIYNKDGNKLDLYGKAVGRHVWTTTGDSKN
                     ADQTYAQIGFKGETQINTDLTGFGQWEYRTKADRAEGEQQNSNLVRLAFAGLKYAEVG
                     SIDYGRNYGIVYDVESYTDMAPYFSGETWGGAYTDNYMTSRAGGLLTYRNSDFFGLVD
                     GLSFGIQYQGKNQDNHSINSQNGDGVGYTMAYEFDGFGVTAAYSNSKRTNDQQDRDGN
                     GDRAESWAVGAKYDANNVYLAAVYAETRNMSIVENTVTDTVEMANKTQNLEVVAQYQF
                     DFGLRPAISYVQSKGKQLNGADGSADLAKYIQAGATYYFNKNMNVWVDYRFNLLDEND
                     YSSSYVGTDDQAAVGITYQF"
BASE COUNT         7390 a         8166 c         9192 g         7520 t
ORIGIN      
        1 ttattacatt tttcgccgtt tagtgaaaat aaataaaacg gggccgcaaa ggcgccccgt
       61 aatataacgc agccgagagg gtaaacctac cctaagtcac tcatatggcc ttattttgac
      121 cagtatgccg ctttcgcgcg ctgtaattta tcatacgctt ttaacaagga ctgatgcgcc
      181 gggaacgctt gtagatcgtg gtcgacagcc ggtagtccat aaaaagccgc ttcaccgcta
      241 agcgcggtgc tggcggcttc tacagcctct gcgccataca tttttataaa agcattgaga
      301 tattgcagcg gctgacgcgc atcttcttgc gacaggagca gcagcgtttg caggcaacgg
      361 taatagtttg cgcgtaccgg actaaagacc gacgaattga actccatcgt ccattctgtc
      421 cagattagcg cctgctccaa atcgccgccc gctaacgcta gcattgcttt taattcgccg
      481 acgcgcagtg tataccaacc attgtccgct ccggtcgcca gacccaacag ttcacgcacg
      541 cgggtgaaat cgtcaaaacc ttcttcatcc aattgttcaa tcagattgag atagtcttct
      601 ttattccagg cgctaccggg cagcgaaagc agaatctcac gaagatggct acccatattg
      661 ttgttggcca gccacagatc ttcggcagga taaatatcag acattcccgg tacgataata
      721 cgacaggcgt atacgccgag atgctcgtaa tcggcaatgt aaacttcttt atcttcagca
      781 gcgaagatgg ccatcagcgt ggcgaattct tcttcggtag tgccggagaa actccagtcc
      841 gtgaacgggt aatcggcgtc ctgtttgaac agatcccagg aaatcaggcc gctggagtcg
      901 atgaagtggg tctccagatt agtgtgctcc gcgacttctt catcatcgaa cgttggcggc
      961 gtgaagacat caagatcttt cagaccgcgt ccctggagta gctcggtcac tgtacgttcc
     1021 agcgcaacgc caaagtcagg atgggcgcca aaagaagcaa agcaggtacc gttagccggg
     1081 ttgaacagca cgacgcagat aaccggatac ttaccgccca gcgagccgtc ataggcgaaa
     1141 atcgggaaac cctcggcttc cagcgtggcg attgactcca ttaccgccgg ataacgcgcc
     1201 atcacctctg cgggaatctc cggcagactg atactttccg caatgatgcg atttttcaca
     1261 taacgctcga agacttccga cagtccctga acgcgggctt cattacgcgt attgccggcg
     1321 gacattccgt tagagacgta caggttgccg ataatattca tcggaatata cacggtctgg
     1381 ttatcggact gacgggtaaa tggcaggccg cagacgccgc gttcttcatt gccggactga
     1441 agatcaatta actggcttcc ggtgagttca ttttccggat cgtaaaacgc gcgcagacgg
     1501 gcatcaagca agccttccgg tacgtcgtca ttttcagtca gcgagaacca cttttcattc
     1561 ggataatgca cgaatggccc gttggcgatc gtttcgccaa gccagaaatc agcaaaaaag
     1621 tagttggttg acagacgctc gaagtattcg cccagcgccg aggccagcgc cgcttttttg
     1681 gtcgcgcctt ttccgttggt aaagcataac gcgcactctt tatcgcgaat atgcactgac
     1741 cagacgtttg gcaccgggtt cagccaggag gcctcttcga tgtgaaagcc gaggtcgagt
     1801 aacttttgct ggaagcgggc gatggagtct tccagcgcgg cgtctttgcc gggaataaat
     1861 gtttgcgtca tgaaaatcac ttttgtcgta cggaaagcgc gcaatgatac gggttttatg
     1921 tgacgggcgc tatctcgccg ggacgtcggc ggaaataaaa gtattggcta tgcttttaca
     1981 ctggaattca caggaagagc ataaaaaatg aaagcatttg atttgcaacg aatggcgctg
     2041 gataacgtgt cggtagcgtt tttgggggaa gtggcgctac gtagctttta cacctttgtt
     2101 ctggtgtttc ttttcttaaa ggtgacagga cgacgcggcg tacggcaaat gtcgcttttt
     2161 gaagtgctga tcattttgac attgggatcg gcggcaggcg acgtcgcgtt ttatgatgac
     2221 gttccgatgc tccctgttct ggtggtattc atcaccctgg cgctgctcta tcgcctagtc
     2281 atgtggctga tggcgcatag tgaaaagttg gaagatctgc tggaaggcaa gtcggtggtc
     2341 attgttgaag acggcgaact ggcgtgggaa aaactgcagc gctcgaacat gacggagttt
     2401 gaatttttta tggagcttcg cttgaatggc gttgagcaac tggggcaggt cagactggcc
     2461 atcctggaga caaacggaca aatcagcgtc tatttctttg aaaataaaga cgttaagccg
     2521 gggttaagca ttcttcctga gcactgtacg ccacgcttta tcgtggcgcc ggaggctggc
     2581 gactatgcct gcgtacgttg cagtgaagtg atacgcatga atgtcgggga gaagcaatta
     2641 tgtccgcgct gcgcaaatcc agaatggacg aaggcaagcc gggctaaacg cgttgtttaa
     2701 cagcgaaaat atcggattta tacggttaat ccggaagatt ctgttgtgtg acgcatgccg
     2761 cattttctcc tcgcattgtt ttacccattg cggcgcgtgt cactgaatga taaaaccgat
     2821 attcacatga ataacgtttg cctgatgtct gtcaggcagg aaacaatgca gcgtggtgag
     2881 gggaaatggc tcaggtcttt aattttagtt caggtccggc gatgctaccg gcggaagtac
     2941 ttaaactggc gcaacaggaa ctgcgtgact ggcacggtct tggtacgtcg gtaatggaaa
     3001 ttagccatcg aggcaaagag tttatccagg tcgctgaaga ggcggagcag gattttcgcg
     3061 atctccttaa tatcccctcc aactataaag ttttattttg tcacggcggc ggtcgcgggc
     3121 agtttgctgg cgtgccgctc aatctgctgg gcgataaaac cacggcggat tatgtcgatg
     3181 ccggttactg ggcggcgagc gccatcaaag aagccaaaaa atactgtgcg ccgcagatta
     3241 tcgacgccaa aatcaccgtt gacggcaaac gtgccgtaaa accgatgcgc gagtggcagc
     3301 tttccgataa cgccgcttat ttacactatt gcccgaatga gaccattgac ggcatcgcca
     3361 tcgatgaaac gccggatttt ggcccggaag tggtcgtcac ggcggatttt tcttctacca
     3421 tcctgtctgc gccgctggac gtctctcgct atggcgtaat ttatgctggc gcgcagaaga
     3481 atatcggtcc ggcaggactg acgctggtta tcgtccggga ggatctgtta ggcaaggcgc
     3541 atgagagctg cccgtccatc ctcgactaca ccgtcctgaa tgataacgac tcgatgttta
     3601 atacaccgcc gactttcgcc tggtatcttt ccggtctggt gttcaaatgg ttgaaagcgc
     3661 agggcggcgt ggcggcgatg cacaaaatca atcagcaaaa agcggagttg ctgtatggtg
     3721 tgattgataa cagcgatttc taccgtaacg atgtcgcaca ggccaaccgt tcgcggatga
     3781 atgttccgtt ccagttagcg gacaatgcgc tggacaaggt ctttctggaa gagtctttcg
     3841 ccgctggtct gcacgcctta aaagggcacc gtgttgttgg cggtatgcgc gcctctatct
     3901 ataacgccat gccgattgaa ggggtgaaag cgctgaccga tttcatgatc gattttgagc
     3961 gccgccacgg ctaatacgtt tcttttttca tccccacggc cagtctgtgg ggtttttatt
     4021 tctgtttttt gagagttgag tttcatggaa tccctgacgt tacaacccat cgcgcgggtc
     4081 gatggcgcca ttaatttacc tggctccaaa agtgtttcaa accgtgcttt gctcctggcg
     4141 gctttagctt gtggtaaaac cgttctgacg aatctgctgg atagcgatga cgtccgccat
     4201 atgctcaatg ccctgagcgc gttggggatc aattacaccc tttctgccga tcgcacccgc
     4261 tgtgatatca cgggtaatgg cggcccatta cgcgcgtcag gcactctgga actgtttctc
     4321 ggtaatgccg gaaccgcgat gcgtccgtta gcggcagcgc tatgtctggg gcaaaatgag
     4381 atagtgttaa ccggcgaacc gcgtatgaaa gagcgtccga taggccatct ggtcgattcg
     4441 ctgcgtcagg gtggggcgaa tattgattac ctggagcagg aaaactatcc gcccctgcgt
     4501 ctgcgcggcg gttttatcgg cggcgacatt gaggttgatg gtagcgtttc cagccagttc
     4561 ctgaccgctc tgctgatgac ggcgccgctg gcgcctgaag acacaattat tcgcgttaaa
     4621 ggcgaactgg tatcaaaacc ttacatcgat atcacgctaa atttaatgaa aacctttggc
     4681 gtggagatag cgaaccatca ctaccaacaa tttgtcgtga agggcggtca acagtatcac
     4741 tctccaggtc gctatctggt cgagggcgat gcctcgtcag cgtcctattt tctcgccgct
     4801 ggggcgataa aaggcggcac ggtaaaagtg accgggattg gccgcaaaag tatgcagggc
     4861 gatattcgtt ttgccgatgt gctggagaaa atgggcgcga ccattacctg gggcgatgat
     4921 tttattgcct gcacgcgcgg cgaattgcac gccatagata tggatatgaa ccatattccg
     4981 gatgcggcga tgacgattgc caccacggcg ttgtttgcga aaggaaccac gacgttgcgc
     5041 aatatttata actggcgagt gaaagaaacc gatcgcctgt tcgcgatggc gaccgagcta
     5101 cgtaaagtgg gcgctgaagt cgaagaaggg cacgactata ttcgtatcac gccgccggcg
     5161 aagctccaac acgcggatat tggcacgtac aacgaccacc gtatggcgat gtgtttctca
     5221 ctggtcgcac tgtccgatac gccagtcacg atcctggacc ctaaatgtac cgcaaaaacg
     5281 ttccctgatt atttcgaaca actggcgcgg atgagtacgc ctgcctaatt cttctgttgc
     5341 gccagtcgac gggctggcgc gtcgagtccg tattcgcact atttttataa ttatgactaa
     5401 tgctaatttg ttggtgattt aacacattga tttatgtgtt ttttataata gttatcaacg
     5461 gaagattagt atgaaaaata aatcattact actggcggtg gcgatttccg ccacgctact
     5521 ggcaggatgt aaaaatggcg tgaatggcaa tttaatcgcc agttccggca tgtcagccta
     5581 caaagccgcc acactgtccg atgcggatgt taaagcatta tctaataatg cctgtaaaca
     5641 aatggacagc gagaatcaac tggcaggttc gaaaagcaaa tacaccaaac gtctgagtaa
     5701 aatcgctaaa gcgctgggta acaacattga cggtacgccg gttagctata aagtctatat
     5761 gaccagcgat atcaacgcat gggcgatggc gaacggttgc gttcgcgtat actccggcct
     5821 gatggatctg atgaccgata atgaaattga aggcgtactg ggccatgaat tgggccatgt
     5881 ctctttaggg cactcccgca aggcaatgca gaccgcctat gccacgctgg cggctcgcga
     5941 tgcgatttcc gccaccagcg gcgtcgcagc gcagctttcc cagtctcaat tgggcgatct
     6001 ggcggaaggc gtcatcaatt tggcgttttc tcgcagtcag gagtcggatg cggatgactt
     6061 ctcttacaat ctgctgaaaa aacgtgggat taacacccag ggcttagtca cggcattcga
     6121 taaattcgcc ataatggacg caggtcatgc aaaatcattg atggactccc acccggcctc
     6181 agccgatcgc gcgcagcata tgcgcgacag aattgccgaa gataaaaagt aaatcattgt
     6241 catctttcgg gctggtttct cgccagcccg ctataattgc gcaattattc cgcatctgat
     6301 tacagacaaa actggttttt gcacgcaacg ttaacggtcg cgagcgttgg cgcgtataat
     6361 gcgcggcgtt tacgttaacg gtacgcctgt ttaaggagat aaagatgacg gcaattgccc
     6421 cggtaataac cattgatggc ccaagcggtg caggtaaagg caccttgtgc aaagcaatgg
     6481 cggaagcatt gcaatggcat ctgctggatt ccggcgcgat ataccgcgta ctggcgctgg
     6541 cggcattgca ccaccatgtc gatctcgcct ctgaagatgc gctggtgccg ctggcgtccc
     6601 atctggacgt gcgtttcgtc tcaacggacg gcaacctgga agttatcctg gaaggcgagg
     6661 acgttagcgg cgaaattcgt acgcaggaag tcgcgaacgc ggcatcccag gtggcggcat
     6721 tcccacgcgt gcgtgaagcg cttcttcgcc gccaacgcgc attccgcgaa gcgcctggtt
     6781 taatcgccga tggacgcgat atggggaccg tggtcttccc ggatgcgccg gtaaaaattt
     6841 tccttgacgc ctcctcggag gaacgtgcgc atcgacgtat gctacagttg caggagaatg
     6901 gctttagtgt taactttgaa cgccttttgg ccgagatcaa ggaacgcgac gatcgcgatc
     6961 gtaatcgcgc tgtagcgccg ttagttcctg ctgctgatgc attagttttg gattctaccc
     7021 gattaagcat tgagcaagtg attgaaaaag cgttacaata tgcgcgccaa aaattggctc
     7081 tcgcttaaat gcgaccgaat ttgtagtacc cccgttgcaa aggattgaca gcgggtatgt
     7141 taaacaaccc catccggcac ggagccaggt ggacgttaaa tatgaaacct gaagattaaa
     7201 catgactgaa tcttttgctc aactctttga agaatcctta aaagaaatcg aaacccgccc
     7261 gggttccatc gttcgtggtg ttgttgttgc tatcgacaaa gacgtagtac tggttgacgc
     7321 cggtctgaaa tctgagtctg ccattccggc tgagcagttc aaaaacgccc agggcgaact
     7381 ggaaatccag gttggtgacg aagttgacgt tgctctggat gcagtagaag acggcttcgg
     7441 tgaaactctg ctctctcgtg agaaagctaa acgtcacgaa gcatggatca cgctggaaaa
     7501 agcttacgaa gatgctgaaa ctgttaccgg tgttatcaac ggcaaagtta agggtggctt
     7561 cactgttgag ctgaacggta ttcgcgcgtt cctgccaggt tctctggtag acgttcgtcc
     7621 ggtgcgtgac actctgcacc tggaaggcaa agagcttgaa ttcaaagtaa tcaagctgga
     7681 ccagaaacgt aacaacgttg tggtttctcg tcgtgccgtt atcgaatccg aaaacagcgc
     7741 agaacgcgat cagctgctgg aaaacctgca ggaaggcatg gaagttaaag gtatcgttaa
     7801 gaacctcact gactacggtg cattcgttga tctgggcggc gttgacggcc tgctgcacat
     7861 cactgatatg gcctggaaac gcgttaagca tccgagcgaa atcgtgaacg ttggcgacga
     7921 aatcaacgtg aaagtgctga aattcgaccg cgagcgtacc cgtgtatccc tgggcctgaa
     7981 acagctgggc gaagatccgt gggttgctat cgctaaacgt tatccggaag gtaccaaact
     8041 gaccggtcgc gtgaccaacc tgaccgacta cggctgcttc gttgaaatcg aagaaggcgt
     8101 tgaaggcctg gttcacgttt ccgaaatgga ctggaccaac aaaaacatcc acccgtccaa
     8161 agtggttaac gttggcgacg tagtggaagt gatggttctg gatatcgacg aagaacgtcg
     8221 tcgtatctcc ttagggttga agcagtgcaa atctaacccg tggcagcagt tcgcagaaac
     8281 ccacaacaag ggcgaccgcg ttgaaggtaa aatcaagtct atcactgact tcggtatctt
     8341 catcggcctg gacggcggca tcgacggcct ggttcacctg tctgacatct cctggaacgt
     8401 tgcaggcgaa gaagcagttc gtgaatacaa aaaaggcgac gaaatcgctg cagttgttct
     8461 gcaggttgac gcagaacgtg aacgtatctc cctgggcgtt aaacagctcg cagaagatcc
     8521 gttcaacaac tgggttgctc tgaacaagaa aggcgctatc gtaaccggta aagtcactgc
     8581 agttgacgct aaaggcgcaa ccgtagaact ggctgacggc gttgaaggtt acctgcgtgc
     8641 ttctgaagca tcccgtgacc gcgttgaaga tgcgactctg gttctgagcg ttggcgacga
     8701 cgttgaagct aaattcaccg gcgttgatcg taaaaaccgc gcaatcagcc tgtctgttcg
     8761 tgcgaaagac gaagctgacg agaaagatgc catcgcaact gttaacaagc aggaagatgc
     8821 aaacttctct aacaacgcaa tggctgaagc attcaaagca gctaaaggcg agtaatcctc
     8881 tgaaacttcg ggccttttag tccgaagtat aacgagatta cttgacagat tgcaggtttc
     8941 ggcctgtaat caagcactaa gggcggctac ggccgccctt aatcaatctc acggctgcag
     9001 ccaatttgcc tttaaggaac cggaggaatc atgaccaagt cagaattgat tgaaagactt
     9061 gcaacccagc aatctcacat tcccgctaag gcggttgaag acgcggtaaa agagatgctg
     9121 gagcatatgg cctcgactct tgcgcagggc gagcgtattg aaatccgcgg tttcggcagt
     9181 ttttctttgc attaccgcgc gcctcgtacc ggacgtaacc ccaagaccgg cgataaagtg
     9241 gaactggaag gaaaatacgt tcctcacttt aaaccgggta aagaactgcg cgatcgcgcc
     9301 aatatttacg gttaagtttt aacgcaaaac ttgaacccga aaaaagcacc gtcagggtgc
     9361 ttttttcatt tatacgccgt caggcgcaaa cgctattcga ccgaaaactg gaaaacgttt
     9421 cgcatttttt gctgcgtctt acatttatca ggtaaaaaac ctggaatccg cgccgtatag
     9481 cacaaaatcc cctccagaca atggcgtcct gaacctgcac actttcccgc acagggaggt
     9541 gtctatgaag ataacgacgg tcagcgtatg cgtagtatgc ggcatacttc cgctcatgat
     9601 attgccagta ttacctgata cgtggattct cgcggtgctg ttttgtctgg catgtttgct
     9661 ttgcctcata ccccatcact atgcgcgcta cgcggcatta accttgctct ttttcatgtg
     9721 ggggattttt gccgccaggc aggccatctg ggtgggaaac gtcctgcccg ccgcgacgca
     9781 ggaggcgaca gtcgtcatta ctgccaccga tcatatgacc actcattatg ggcgaattac
     9841 ccatttgcat ggaaagccac tctttcctgc tgtagggatt gtcctgcatg gccagtactt
     9901 acccacggaa gtgtgtgccg gacagcagtg ggcgatgacg ctgaaggtca gagcggtaca
     9961 cggacagctt aacgaaggcg gttttgatag ccagcgttac gcgctggcgc agcaccaacc
    10021 gttgaccggg cgttttctac aggctaaagc gattaaccct gagtgtagct tgcgtgggcg
    10081 ctatcttgct tcgcttcgcg ctacgcttgc gccttatccg tggcagcagg ttattctggc
    10141 gttgggaatg ggggagcggg gagcggtgtc gcaggaggtg aaggccgtta tgcgcgatac
    10201 ggggactgcc catttgatgg cgatttccgg cctgcatatc gcttttgctg cgttattggc
    10261 tgccggatta atccgtggcg gacaattctt tttgccggtc agatggattc gttggcagac
    10321 gccattgctg ggcggcattc tttgcgcgat atgttatgcc tggcttaccg gcttacaacc
    10381 gcctgcgctg cgcacggtgg cggcactgag cgtctgggga ggattgaaat taagcggacg
    10441 acagtggagc ggctggcaag tctggtgctg ctgtctggcc gcgattattt tcgccgatcc
    10501 tgtggcggtt atatcacaaa gtctttggct gtcagcattt gcggttgccg gcctgttatt
    10561 ctggtatcag tggtttcctg cgccaaacgg aaattttcca cgaggcttac gctggttgct
    10621 taacctgctt cacctacagg caggcattac acttctgctt ttgcctctcc aggtggcgct
    10681 ttttcatggc ataagcgtta ccgcaatgct ggcgaatctt tttgccgtac cttgggtcac
    10741 atttgtgacg gttccactca tcctggcggg aatgattctg catttaaccg ggccgttttt
    10801 tcttgaagag tgggtatggt acctgaccga tcgcgcgtta gccgcgctat tttacctgtt
    10861 gaatgcttta ccgcagggct gggtgaatat tgataaccgt tggcagtggc tgacgctttt
    10921 accctggcta acgcttatcg cgtggcgatt aaacgtctgg cgtacctggc cggcggtctg
    10981 tttatgcggg ttattgttga tgagctggcc actctggcgg ccgataaacg ccagcggatg
    11041 gcaggtgcat atgctggatg tcggtcaggg gctggcgata gcgatcgtca ggggcgataa
    11101 agtaatactc tacgataccg gtcgggcatg gccggagggc gacagcgggc aacaggttat
    11161 tattccctgg ttgcgctggc ataatctgac gccggagggc gttattttga gtcatgagca
    11221 tctggatcat cggggcgggc tgcgttcgct acagcaggtc tggccgtcaa tgtggattcg
    11281 cagcccgtta ggctggcagg gacatttgcc ctgttttcgc ggcgagcagt ggcaatggca
    11341 ggggctaacg tttcaggcgc actggccgtt acgcgaaagt gccgatcgag gaaataaccg
    11401 ttcttgtgtg gtcaaagtgg atgacggtgt acatagcatc ctgctcacgg gcgatatcga
    11461 agcgggcgct gaacaaaaaa tgctaagtcg ttactggcga catcttgcgg cgacgtttat
    11521 ccaggtgccg catcatggta gtaatacgtc gtcgtcgtta ccatttattc agcgcgtaca
    11581 tggtgaagcg gcgctggcgt ccgcatcgcg ctataacgca tggcggctgc cgtcccgcaa
    11641 ggtaaaacag cgctaccgac agcaggcgta tcagtggttt gatacacccc accaggggca
    11701 aatttcgctg ctgttttctc cgcagggctg gcgcatacaa ggcttacggg atcaaatttt
    11761 acctcgctgg tatcatcagt ggtttggcgt gtccgaggat aacgggtaga atatgcggct
    11821 atttcaacaa atgctggttt tttgaatgca taacgataaa gatctctcta cgtggcagac
    11881 cttccgccga ctgtggccaa ccatagcgcc ttttaaagca ggtctgatcg tggcgggcat
    11941 agcgttaatt ctcaacgcag ccagcgatac cttcatgcta tcgctcctca agccattact
    12001 ggatgatggt ttcggtaaaa cggatcgctc agtgttgctg tggatgccgc tggtggttat
    12061 tgggctgatg atattacgag gcatcactag ctatatctcc agctactgta tttcatgggt
    12121 gtcaggcaag gtggtaatga ccatgcgccg tcgcctgttt ggccatatga tgggaatgcc
    12181 cgtcgccttc tttgataaac agtctaccgg tacgctgctg tcgcgtatta catacgattc
    12241 agaacaggtt gcctcttctt catctggcgc gctgattacc gtggtgcgtg aaggggcatc
    12301 gatcatcgga ttgtttatta tgatgttcta ttacagctgg cagctgtcga tcatcctggt
    12361 tgttttagcg ccgattgtgt cgattgcgat tcgcgttgtc tcaaagcggt tccgcagcat
    12421 cagtaaaaat atgcagaaca cgatgggaca agtgactacc agcgctgaac aaatgctgaa
    12481 aggacacaaa gaggtactga ttttcggcgg tcaggaagtc gaaactaaac gctttgataa
    12541 agtcagcaat aagatgcgac tgcaaggcat gaaaatggtc tctgcctcgt caatttccga
    12601 tcctatcatt cagctcattg cctcgctggc gctggcgttt gttctctatg ctgcgagctt
    12661 cccaagcgta atggatagcc tgacggcagg gaccatcacg gtggtgttct cctccatgat
    12721 cgcgctgatg cgtccattaa aatcgctgac aaacgttaac gcgcagttcc agcgtgggat
    12781 ggcggcttgt cagacgttgt ttgcgattct ggacagcgaa caggagaaag atgaaggtaa
    12841 acgtgtcatt gaccgcgcga ccggcgatct cgaattccgc aatgtgacgt ttacttaccc
    12901 gggccgtgaa gtgccggcat tgcgtaacat caatttgaaa attcctgccg ggaaaaccgt
    12961 ggcgctggtg gggcgttccg gatcgggtaa atcaactatc gccagtctga tcacccgttt
    13021 ctacgatatt gatgaaggac acatcctgat ggatggtcac gatctacgcg aatacactct
    13081 ggcctctcta cgtaatcagg tggcgctggt ttcgcaaaac gtgcatctgt ttaacgacac
    13141 ggtcgccaat aacattgctt atgcccggac ggaagaatac agccgcgagc agattgaaga
    13201 ggcggcgcgc atggcctatg ccatggactt tatcaacaag atggataatg gtctggatac
    13261 cattatcggc gaaaacggcg tactgctttc cggcggtcag cgccagcgta tcgcgattgc
    13321 ccgcgcctta ctgcgcgaca gcccgattct gatccttgat gaagctacgt ccgcgctgga
    13381 taccgagtcc gaacgtgcga ttcaggccgc gttggatgag ctgcaaaaaa accgtacctc
    13441 tctggtgatt gcgcaccgtc tctccaccat cgaacaggcg gatgagatcg ttgtagtcga
    13501 agacggtatt atcgttgagc gcggcactca tagcgagctg ctggcgcaac acggcgttta
    13561 cgcccagctg cataagatgc aatttggcca atgattgcgc gtatctggtc gggtgaatcc
    13621 ccgctatggc ggttactgct gccgctctcc tggctgtatg gcctggtgag cggggcgatt
    13681 cgtctgagct ataagcttgg tttgaaacgc gcctggcgag cgccggtacc ggtggttgtg
    13741 gtagggaatc ttacggctgg cggtaacggt aaaacacccg tagtcatttg gctggtggaa
    13801 aagctgcaac agcgtggcgt gcgcgtgggg gtcgtttccc gcggctacgg cgggaaagct
    13861 gccgcttatc cgctgctcct gacgcctgag acgacaaccg cagaagcggg agatgaaccg
    13921 gtattgattt atcagcggac cggcgcgcct gtcgcggtgg cgcctgaacg cgccgcggcg
    13981 gtgaaagcga ttctggcggc gcataatgtg cagattatta tcaccgacga tgggttgcag
    14041 cattaccgac tagcgcgaga tattgaaatt gtggtgattg acggggtgcg ccgttttggc
    14101 aacggctggt ggcttcctgc cggccctatg cgcgaacgcg ccagtcgcct gaaaaccgtg
    14161 gacgccgcta tcgtgaatgg cggcgtcgcc cgggcgggcg aaatccccat gcagctagcg
    14221 cctggactgg cggtgaactt acgtacggga gcgcgttgcg atgtggcgca actgagcaat
    14281 attgtggcga tggcgggcat cggtcatccg ccgcgctttt tcgccacgct ggaagcctgt
    14341 ggcgcgcatc cgcaaaagtg cgtcccgctg gccgatcatc aaacgctcgc ccctgctgac
    14401 gttcaggcgt tggtcggtga agggcagacc ctggtaatga cggaaaaaga cgcggtgaaa
    14461 tgccgtgctt tcgccgaaga taactggtgg ttcttaccgg ttgatgcgcg tttgtccggc
    14521 gagcagcctg ataagttgct tgaacatatc acctcgctgg ttcgctagcg taccccaatg
    14581 cagcggcagt gatgaattta tggagtcatg aatgtcattg ccgtaccttt ctctttccca
    14641 ggcccgttgt cttcaccttg ctgcgcaggg gctattgaaa aagccgcgcc gtaacgcgat
    14701 gcctggcgat gttcttgccg ccatctcacg catggcgttg ctgcaaattg ataccatcaa
    14761 tgttgtcgca cgtagcccct atctggtgct gtttagccgt ctcggttcgt acccgcaggc
    14821 ttggctggat gaggcgctgc gacgcggcga gttaatagaa tactgggcgc atgaggcctg
    14881 tttcttacca cgccgcgact ttaaacttat ccgccatcgt atgctgtcgc cggaaaaaat
    14941 gggctggaaa tatcgcgcgg catggatgca tgagcacgcg gaagaaatag aacagctggt
    15001 gcggcatatt caggagcatg gtccggtgcg ttctgccgat tttgaacatg cgcagaaagg
    15061 cgtcagcggc tggtgggaat ggaaaccaca taaacgccac cttgagggtt tatttaccgc
    15121 cggaaaagtc atggttgttg agcggcgtaa ttttcaacgt gtatatgatt taacgccccg
    15181 tgtgatgccg cactgggatg atgaacgcga tggactgtca cagccgcagg cggaaagcct
    15241 gatgctggat aatagcgcgc gcagtctggg gattttccgt gaacagtggc tggcggatta
    15301 ctaccgcctg aaacgtcctg acctgaaagg atagcgggag agccgggcgg aacagcagca
    15361 gattattccg gtcgaggtgg aaacgttggg gcggatgtgg cttcatgccg atcttctttc
    15421 gcagcttgaa ccggcgctaa ataacgcctt aaaggcgacc catagcgcag tactgtcgcc
    15481 tttcgatcct gtggtatggg atcgtaagcg ggcagcgcag ctcttcgcat tcgactaccg
    15541 gctggaatgt tatacgcccg cggcgaagcg ccagtacggt tattttgtgc tgccgctatt
    15601 ataccagggc cgtttagtcg ggcgaatgga cgccaaaatg caccgtaaaa cgggggtgct
    15661 tgaggttatc tcgctgtatc tggaggacga tattcgccct ggcgttagtc tgcaaaaagg
    15721 aatctggcag gccattagcg cgtttgctgc ctggcaacga gcatcgcgcg tgacgctggg
    15781 acaatgtccg ccaggcctgt ttagcgccat gcgtcatggc tgggaaatag accctgcacc
    15841 ataaccgatt atgttaatat tgaaggattc acaatccggt ccatctggag gaactatgga
    15901 tcatcgtctg cttgaaatca tcgcctgccc ggtatgtaac ggcaaactct ggtataacca
    15961 ggaacagcaa gaattaattt gcaaactgga taatctcgct ttcccgttac gcgacggcat
    16021 tcctgtattg ctggaaaatg aagctcgcgc cctgacatct gatgagagta aatcatgagt
    16081 ttcgtcgtca tcattccggc ccgtttttca tctacccgac tgccaggcaa accattagtg
    16141 gatattaatg gtaaacccat gattgttcat gtcctggagc gggcgcgcga atctggcgcg
    16201 gaacgcatta ttgtcgcgac cgatcatgaa gacgtggctc gtgcggtaga agcggctggc
    16261 ggcgaagtgt gcatgacgcg cgccgatcac cagtccggca ccgaacggtt ggcggaagtg
    16321 gtagagaagt gcggattcac cgacgatacc gttattgtga acgttcaggg cgatgagccg
    16381 atgatcccgg cggttattat tcgccaggtc gcggaaaatc tggcgcagcg ccaggttggc
    16441 atggcgacgc tggcggtgcc gattcacagc gccgaagaag cgtttaaccc gaatgcggta
    16501 aaagtcgtgc tggatgctga aggctatgcg ctttactttt cccgggcgac gattccctgg
    16561 gatcgcgatc gctttgcaaa aagtctggaa acggtagggg atacttgcct tcgtcacctg
    16621 ggcatttatg gctatcgcgc gggatttatc cgccgttacg tgagctggca acccagcccg
    16681 ctggaacata ttgaaatgct ggagcaactc cgtgtgctgt ggtacggcga aaaaattcat
    16741 gtcgctgtcg ccaaagcggt gcccggcacg ggcgtagaca ccgccgacga cctggagcgc
    16801 gtgcgcgctg aaatgcgtta acatgatcct gttcatgatc gtcttagacg gtcatgaaca
    16861 gcgcggtatg atagcgcaaa gatgaatact cacgtctgct catcagtggc ggctttctcg
    16921 taccgttacg attttcctca tttttctttt cttcccttga tctgatacgg gtgacatctg
    16981 tccatacgac gctcattatt aaagcagtag cactaatggg ggtaatctgg aatggaacag
    17041 ttgcgggccg aactcagtca tttgttgggt gaaaaactta gccgtataga gtgcgtgaat
    17101 gagaaagcgg attccgcatt gtggtcatta tatgacagcc agggaaatcc gatgccgctg
    17161 atggcgcgaa gttttaccac tcctggcgtt gcgcagcaac tggcatggaa aacctcaatg
    17221 ctggcgcgta gcggtacggt gaggatgccg gtaatctatg gcgtattgac gcatgaagag
    17281 catcctggtc tggatgtgct gctactggaa cgactgcgcg gtgtgccggt cgaggcgccg
    17341 gcgcgcactc cggaacgctg ggaacagcta aaagatcaga ttgtcgaagg attgttagcc
    17401 tggcatcggc aggatagccg cggttgcgtg ggcgccgtag accatactca ggagaatatc
    17461 tggccttcct ggtatcgtca gcgtgtggag gtgctgtgga cgacgctaaa tcagttcagc
    17521 aataccggcc tgacgatgca ggacaaacgc attctgtttc gtaccagaga atatcttcct
    17581 tcgttatttg aagggtttaa cgacaactgc gtactggtgc atggcaactt ctgcttgcgc
    17641 agtatgctta aagacgcccg tagcgatcag cttctggcga tggtcggccc cgggctgatg
    17701 ctgtgggcgc cgagagaatt cgaactgttt cgcctgatgg ataatccatt ggcggaggga
    17761 ttgctttggc attatctgca acgcgcgcca gtggcggagt cattcatctg gcggcgttgg
    17821 ctctatgtgc tgtgggacga ggttgcgcaa ttggtcaata ccggacgttt taaccgtacc
    17881 aattttgatc tggcggcgaa atcattactc ccctggcttg cctgatatgc ctttcagcca
    17941 ttgccaaagt cgccctaatg tttcataccc agcgcgatcg ctgtgcatca gccagaccgg
    18001 ggacggaatt gcccgctccc agggattgag cggcgaatcg atcgccaact gattcgccgg
    18061 cgcgggaagc ggattcagcc cggcatgctg aaagaaaatc atcgcacgcg gcaaatgcga
    18121 ggcggaggtt accagcagga aaggggcgtc gccgatggcc tgcttaacgg cggcggcttc
    18181 ttcttccgta tcttttggct tatccagcgt aataatatcg ctacgcggta cgcccagcga
    18241 ctgcgccacc cgcgcgccga cttccgccgt gcttaccgta ttggtttttg ctacgccgcc
    18301 ggtaaaaatc agcctggctc ccggattcgc gcgccacagc cgaatgcctt ccgccagccg
    18361 cggcaagctg ttgttaatta aattagagct cggcgcccac tgcgggttcc aggtatagcc
    18421 gccgccgaga accacaatat attccacctt ttgcggaccc tgccaggtag ggtagcggtt
    18481 ttctatcgga cgcagcaaat ggtcagagac gggttgcagg cttaatagca atagcgccag
    18541 ccaacctacg ctgataaata cttttccggt cttctgaaag cggctaaacc agagcagcgc
    18601 caggccgatg ccaatgatca gcaacatcag cggaagcggc aataacatgc cgccaatcac
    18661 tttctttagc gtaaaaagca tcctttttgg ttcctttttt aaccatatag cggaggatta
    18721 acggtgatat tacaccagac aggttcattc tcgccgcggc tgtgacaaaa tagcggtttt
    18781 atcagataac gcctgagcca gcctgtggag agtccgatgc aggatcgcaa ttttgatgac
    18841 attgctgaaa agttttcccg taacatttac ggcacgacca aagggcaact gcggcaagcc
    18901 attctgtggc aagacctgga tcgcgtgctg gaggagattg gcgggcggaa actgcgggtg
    18961 ctggatgccg gcggcggcga agggcaaacg gcgattaaga tggcggaacg cggccatcag
    19021 gtgacgttat gcgatctgtc tggcgaaatg atcgcccgcg cgcggcaggc ggccgaggca
    19081 aaaggtgtga gcaaagacat gcattttata caatgcccgg ctcaggacgt cgcttcgcat
    19141 ttggaaagcc cggttgatct gatattgttt catgctgtgc tggagtgggt agccgatcct
    19201 gtcggcgtat tagaaacgct ctggtcagta ttgcgccctg gcggcgcgct gtcgttgatg
    19261 ttctataacg ctaacggttt gctgatgcac aatatggtgg cgggtaattt tgactacgtg
    19321 caggcgggga tgcctaaacg caagaagcgc acgctgtcgc ctgactaccc gcgcgacccc
    19381 gcgcaggtgt accagtggct ggaggcgatt ggctggcaga ttaccggtaa aaccggcgtg
    19441 cgtgtgtttc atgattatct gcgtgaaaaa caccagcagc gtgactgtta tgagaccctg
    19501 gtcgaactgg aaacgcgtta ttgccgccag gagccgtata ttagccttgg gcgctacatt
    19561 catgtcaccg cgattaaaag cccggcgcta gccgcagatg caaggataac ctatgagtga
    19621 attttcccag acagtccccg aactggttgc ctgggccaga aaaaacgact tttccatctc
    19681 gctgccggta gacagacttt cctttctgct ggcggtcgcc acgttgaacg gcgaacgcct
    19741 tgacggcgag atgagtgaag gcgagctggt ggatgcattc cgccatgtga gtgatgcgtt
    19801 tgagcaaacc agcgaaacca tcggcgtgcg cgcgaacaac gcgattaacg atatggtgcg
    19861 tcaacgtctg ctgaaccgct ttaccagcga gcaggcggaa ggcaatgcga tttaccgatt
    19921 aaccccgctc gggattggca tcaccgatta ctacattcgt caacgcgaat tctctacgct
    19981 gcgtctttct atgcagttgt cgattgtggc cggcgaattg aagcgcgcgg cggatgcggc
    20041 agcggagggg ggcgatgagt tccactggca tcgcaatgtt tacgcgccat tgaaatattc
    20101 ggtggcggag attttcgaca gtatcgatct cacccagcgc attatggatg aacagcagca
    20161 gcaggtgaaa gacgatatcg cacaactgct gaataaagac tggcgggcgg cgatttccag
    20221 ctgtgagctg ctgctttccg aaacgtccgg tacgctgcgc gagttgcagg atacgctgga
    20281 ggcggcgggc gataagctgc aggctaacct gctgcgcatt caggatgcca cgatgacgca
    20341 cgacgatctg cattttgtcg acaggctggt gtttgactta caaagtaaac tcgaccgcat
    20401 tatcagttgg ggtcagcagt ctattgattt atggatcggc tacgatcgtc acgtgcataa
    20461 atttatccgt accgcgatcg atatggataa aaaccgtatc ttcgcccagc ggttgcgcca
    20521 gtccgtgcag acttattttg acgatccgtg ggcgctaacc tacgcgaatg ccgatcgtct
    20581 gctggatatg cgcgatgaag agatggcgtt gcgtgacgat gaagtcaccg gggagttgcc
    20641 gccggatctg gaatatgaag agtttaacga gatccgcgag cagttagcgg ccatcattga
    20701 agaacagctg gctatctaca aaaccagaca aacgccactg gatcttgggc tggtggtgcg
    20761 cgagtatctg gcgcaatacc cgcgcgcgcg tcatttcgac gtggcgcgta ttgttatcga
    20821 tcaagcggta cgtcttggcg tagcgcaagc agatttcacc ggactgccag ccaaatggca
    20881 gccgattaat gattacggag ccaaggtaca ggcgcatgtc attgacaaat attgaacaag
    20941 tgatgccggt taagctggcg caggcgctgg cgaatccgtt atttccggcg ctggatagcg
    21001 cattacgttc gggccgccac atcgggctgg acgaactgga taatcatgcc tttctgatgg
    21061 attttcagga atacctggaa gagttttacg cgcgttataa cgtggagttg attcgtgcgc
    21121 cggaggggtt cttttacctg cgtccgcgtt ctaccacgct tatcccgcgc tcggtgttat
    21181 ccgaactgga tatgatggtc ggtaaaattc tctgctacct ctatcttagc ccggagcgtc
    21241 tggccaacga agggatcttt actcagcagg agttgtacga cgagctgctt acccttgcgg
    21301 acgaagccaa actgctaaag ctggtgaata accgttcgac gggatctgac gttgatcgtc
    21361 agaaactgca ggaaaaggtg cgttcttctt taaaccgcct gcgtcgtttg ggcatggtat
    21421 ggtttatggg ccacgacagc agcaaattcc gcattaccga atcggtcttc cgctttggcg
    21481 cggatgtccg cgccggcgac gatcctcgcg aggcgcagcg tcgtctcatc cgcgacgggg
    21541 aagcgatgcc cattgaaaac catctgcaac ttaatgatga gaccgaagag agtcagccgg
    21601 acagtggaga ggaagaataa tgattgaacg cggtaaattt cgctcgctaa cgctgattaa
    21661 ctggaacggt ttttttgccc gcacttttga cctggatgaa ctggtcacga cgttatccgg
    21721 gggcaacggc gccgggaaat ccacgacgat ggcggcgttc gtcacggcgc tgatcccgga
    21781 tctcacatta ctgcactttc gtaacaccac ggaagccggc gccaccagcg gttcgcgcga
    21841 taaaggtctg cacggtaagc tgaaggcggg tgtctgttac tccatgctcg acaccattaa
    21901 ttcccgccat cagcgggtgg tggtcggcgt gcgtctgcag caggtcgctg ggcgcgatcg
    21961 caaagtggac atcaaaccgt tcgctattca ggggctgccg atgtcggtac agccgacaca
    22021 actggtgacg gagacattaa acgaacgtca ggcgcgcgta ctgtcgcttg ctgagctgaa
    22081 agacaagctt gacgagatgg aaggcgtgca gtttaagcag tttaactcca tcaccgatta
    22141 tcattcgctg atgtttgact tagggattat cgcccgtcgt ctgcgttccg cttccgatcg
    22201 tagtaaattc tatcgtttga tagaggcctc gctgtacggc gggatctcca gcgccattac
    22261 ccgatcgcta cgcgattatt tattgccgga aaacagcggc gtgcgcaagg cgttccagga
    22321 tatggaagcg gcgctgcgcg agaaccgact cacgctggaa gcgattcgtg ttacccaatc
    22381 cgatcgcgat ctgtttaagc atttgatcag cgaagccacc gattatgtgg cggcggatta
    22441 tatgcgccac gccaatgagc gtcgggttca ccttgatcag gcgttggcgt ttcgacgcga
    22501 actgtacaca tcgcgcaaac aactggcggc ggagcagtac aagcacgtcg atatggcccg
    22561 tgagttgggc gaacataacg gcgccgaagg ttctcttgaa gcggattacc aggcggcgag
    22621 cgatcacctg aatctggtgc aaaccgcgct gcgccagcag gaaaaaattg aacgctacga
    22681 agcggatctt gaagagctgc agattcgatt cgaagagcaa aatgaagtgg tggcggaagc
    22741 cgccgaaatg caggacgaaa atgaagcgcg tgccgaagcc gccgagctgg aagtcgatga
    22801 actcaaaagc cagcttgcgg attaccagca ggcgctggat gtacagcaaa cgcgcgcgat
    22861 tcagtataac caggcgatat cagcgcttgc ccgcgctaaa gaactttgcc atctaccgga
    22921 tctaacgccg gaaagcgccg ccgaatggct ggatactttc caggcaaaag agcaggaagc
    22981 tacggaaaaa ctgctgtcgt tggaacaaaa aatgagcgtg gcgcaaaccg cgcacagcca
    23041 gtttgagcag gcttaccagc tggtggcggc gatcaacggc ccgctggcgc gtagcgaagc
    23101 ctgggacgtg gcgcgcgagc tgttacggga cggcgtgaac cagcgtcatc tggcggaaca
    23161 ggtacagccg ctgcggatgc gcctgagcga actggaacag cggctgcgcg agcagcaaga
    23221 ggcggaacgt ctgctggcgg agttctgtaa gcgacagggc aaaaattttg atattgacga
    23281 actggaagcg ctgcatcagg agctggaagc ccgcatcgcg tccttgtctg agagcgtgtc
    23341 gtcagccagc gaacagcgta tggccttgcg tcaggaacag gaacagctgc aatcccgtat
    23401 ccagcatctg atgcaacgcg ctcctgtctg gctggcggcg cagaatagcc tgaaccagct
    23461 tagcgaacag tgcggcgagg agtttacgtc cagccaggaa gtgaccgaat acctgcaaca
    23521 gctactggag cgtgagcgcg aagccattgt cgaacgcgac gaagtgggcg cacgtaaaaa
    23581 tgcggttgat gaagagatcg aacgtttaag ccagccgggc ggtgcggaag atcagcgttt
    23641 gaatgcgctg gcggagcgtt ttggcggggt actgctgtcg gaaatctacg acgatgtcag
    23701 tcttgaagat gcgccgtact tctccgcact gtatggcccg tcgcgccatg cgatcgtcgt
    23761 accggattta tcgcaaatag ccgaacagct tgaaggtctg accgactgcc cggaagatct
    23821 gtacctgatc gaaggcgatc cgcagtcttt tgatgacagc gtattcagcg ttgacgagct
    23881 ggaaaaggcg gtggtcgtga aaattgccga ccgtcagtgg cgttattcgc gtttcccgtc
    23941 gctacctatt tttggccgcg cggcgcgcga gaaccgtatt gagagtctcc atgcggaacg
    24001 ggaagtgctt tccgagcgct ttgccacgct ctcgtttgac gtgcagaaaa cccagcgttt
    24061 gcaccaggcg ttcagccgtt ttatcggtag ccacctttcc gttgcctttg aggacgatcc
    24121 ggaagcggaa attcgccgac tgaacgggcg tcgcgtcgag ctggagcgcg cgctggcgac
    24181 gcatgaaagc gacaaccagc agcagcgcct tcagtttgag caggccaaag agggcgtttc
    24241 cgcgcttaac cgtttgctgc cgcggctgaa tttattggcc gatgaaacgc tggccgatcg
    24301 ggtcgatgaa attcaggagc ggttggatga ggcgcaggaa gcggcgcgat ttgtgcagca
    24361 atatggcaac cagttagcca aactggagcc aatggtttcc gttctgcaaa gcgatccgga
    24421 acagtttgag caattaaaag aagactatgc atggtcgcag caaatgcagc gcgacgcgcg
    24481 ccagcaggct tttgctctgg ctgaagttgt cgaacgtcgg gcgcatttca gctattccga
    24541 ctcggcggaa atgctgagcg gcaacagcga tctcaacgaa aagctgcgcc agcggctgga
    24601 gcaggcggaa gccgagcgta cccgcgcccg cgaagcgctg cgcagccatg ccgcgcagtt
    24661 aagtcagtac agccaggttc tggcctcgct aaaaagctct tacgacacga aaaaagagct
    24721 gcttaacgat ttgcagcgcg aattacagga cattggcgtt cgcgccgaca gcggggcgga
    24781 agagcgcgcc cgccagcgtc gggatgaact gcacgctcag ttgagcaata accgttcgcg
    24841 tcgcaatcag cttgagaaag cgctcacctt ctgcgaagcg gagatggaga acctgacccg
    24901 taagctgcgc aagctggagc gcgattatca tgaaatgcgc gagcaggtcg tgaccgcgaa
    24961 agccggctgg tgcgcggtca tgcggatggt gaaagacaat ggcgtggaac gccgtctgca
    25021 ccgtcgtgag ctggcttatc tgtcggcgga tgaactgcgc tccatgtcgg ataaggcgtt
    25081 gggcgcgctg cgtctggccg tcgcggataa cgaacatctg cgcgacgtat tgcgtctgtc
    25141 ggaagatccg aaacgcccgg aacgtaaaat ccagttcttt gtggccgttt accagcatct
    25201 gcgcgagcgt attcgtcagg atattattcg taccgacgat ccggttgaag ccattgaaca
    25261 aatggagatt gagctgagcc gtctgacgga agagctgaca tcgcgtgagc aaaagctggc
    25321 gatcagttcc cgcagcgtgg caaacatcat ccgcaaaact atccagcgtg agcagaaccg
    25381 tatccgtatg ctgaaccagg gtttgcaaag cgtctcgttt ggccaggtga atagcgtgcg
    25441 gttaaacgtc aacgtgcgtg aaacgcatgc caccttgctg gatgtgcttt cagaacagca
    25501 ggagcagcat caggatctgt ttaacagcaa tcgtctgacc ttctccgaag cgctggcgaa
    25561 actgtaccag cgcctgaatc cgcagatcga tatgggtcaa cgcacgccgc agaccatcgg
    25621 cgaggagttg ctggactacc gtaactatct ggaaatggaa gttgaagtta accgtgggtc
    25681 tgacggctgg ctgcgtgcgg aatccggcgc gctatcaacg ggtgaagcta tcggaacagg
    25741 gatgtcaatt ctggtgatgg tggtgcaaag ctgggaagac gaagcgcgca gactgcgcgg
    25801 gaaagatatt tcgccatgtc gcctgctgtt cctcgatgaa gcggcgcgtc tggatgcgcg
    25861 ctctatcgcc acgctgtttg aactatgcga acgtttgcag atgcagctca tcatcgctgc
    25921 gccggaaaac atcagtccgg agaagggcac gacgtataaa ctggtgcgta aagtgtttca
    25981 gaatactgag catgttcatg ttgtcgggct gcgtggcttt gcgccgcagc ttccggaaac
    26041 gcttcccggt acgcaggcgg aagatacgcc ttcagaagcg agttaaacac ggcagaaacg
    26101 atgaagtgcc tgatggcgcc tcgcttatca ggcaaggccg gataagtcgg ttatgccggc
    26161 atccggcata acaagttctg ctttatcatt agcctggggc ggcgaaagcc gcctttttct
    26221 ttatctgaaa aatctctccg ggtagtgtat tttctttaaa cttctttaca ttaggttagg
    26281 caaaaacgta acgaacttta tatactggag ttaagcctga cgagtgagca ggctgactcg
    26341 tcatactaaa caaaagcatt ggttgaggtt gacccgcgct gcgggcagca cagtcatgcg
    26401 gagtatgata acgaaaacag ggggcaaggg atgttgctta ataagatgtg tggtcgttgt
    26461 ctgtcggcaa tcagtttatg cctggccgta acattcgctc cactgttcaa tgcgcaggcc
    26521 gatgagcctg aaatgatacc tggcgatagc gccgttgccg cgacgggtca ggctgggccg
    26581 cagaagcaat ccgccgcgac ggcgattctg gccgggattc agccgctgcc ggagggcgtt
    26641 tcagccgaga aagttcgggc tgatttacag tcgcagcttc cttccggcta tacgccggtc
    26701 tatatgagcc agctgacatt gctgtatgcc gcgcgcgaca tgaagcccat gtgggataat
    26761 cgcgatgcgg tgaaagcctt ccagcaacag ttggcggagg tggcgatcgc cggattccag
    26821 ccgcagttta ccgcctgggt ggcattgttg accgctcccg ccgtaaacgg tatggcgcgc
    26881 gatgttgtgt tgtcagacgc catgatgggc tatctccatt tcattgcgaa tatccccgtc
    26941 aaaggccaac gctggctata tagcaacaaa ccttacgcat tggcgacgcc gccagtctcg
    27001 gtgattaacc agtggcaaat cgcgctggaa gaggggcagt tgccgatgtt tgtcgccagc
    27061 ctggcgccgc agcatccaca gtatgcgccc atgcatgacg cactgctgaa gctggtggcg
    27121 gactctcgcc cgtggccgca gttgaccaat accgcgacgc tgcgcccggg gcaatggagt
    27181 aacgatgtgc ctgcgctgcg cgaaatatta cagcgtacgg ggatgctgga tggcggtcca
    27241 aagatagcct tacccggcga taacacctct gatagtgccg tcgtcagccc ctccgccgta
    27301 gtcgacgaaa catcggtggc gcagccggtc gacgaaccaa cggcccgccg tagtaagccg
    27361 gctccggcgg cacgcgccta cgatcgtgaa ctggtcgagg cggtaaagcg ttttcaggca
    27421 tggcaaggac tgggggcgga tggcgtcatt ggcccggcga cgcgtaactg gcttaatatg
    27481 acccccgcgc aacgcgcagg cgtactggca ctgaatatcc aacgtttacg cctgctgccg
    27541 gcggaactct ctaccggtat tatggtaaac attcccgctt attcgctggt ctactatcag
    27601 aatggcaacc aggtgctggc ttcaagggtg atcgtcgggc gtcccgatcg taaaacgccg
    27661 atgatgagca gcgcgctgaa taatgtggtg gtgaacccgc cgtggaacgt tccgcccacg
    27721 cttgcgcgta aagacatttt accgaaggtg tggaatgacc caggctatct ggagcgccat
    27781 ggctacaccg tgatgcgcgg ctggaacagc aaagaagcga tcgatccgtg gcaggttgac
    27841 tgggccacca ttacgccatc gaatcttccg ttccgtttcc agcaggcgcc aggcgcgcac
    27901 aattcgctgg ggcgttataa atttaatatg ccgagttcag atgcgatcta tctgcacgat
    27961 acgcctaacc ataatctttt tcagcgtgac gccagggcgt taagttccgg ctgcgtgcgg
    28021 gtcaataagg cctctgaact ggcgaatatg cttttgcagg atgctggctg gaacgatgcg
    28081 cggatctctg gcgccctgaa gcaaggcgac acgcggtatg tcaatatccg gcagaacatt
    28141 ccagtaaatc tttactatct gaccgcgttt gtcggcgcag atggacgtat gcaatatcgt
    28201 acagatattt acaattacga tctcacagcg cgatccagcg cacaaattgt gccaaaggtt
    28261 gaacaattaa tcaggtaaat gaagaagttc tggtaaatat gttgtcctaa tgtttggctt
    28321 caacggggcg tttcgctgta gacccccgtt gtggctgggg gagggccatc ttgacgcggg
    28381 ctttatcgcc agttaaggtg cctttcgtgc gccagaagtg catatacaac aacctttaag
    28441 tcgaccgggc cgttcagaag tctgtgccag ccggtatcat gtctgcttaa aggtagaagt
    28501 gtattaacga taacattgac ctgtagacct gattatcatg gacaaatttg acgctaatcg
    28561 ccgcaagctg ctggcgcttg gtggtgtcgc tctcggcgcc gccatcctgc cctcgccagc
    28621 gtttgccaca ctctcgaccc cacgcccgcg cattttgacg ttaaacaatc tccataccgg
    28681 agagtcaatc aaggcggagt ttttcgatgg aagagcctac attcaggatg aattagcaaa
    28741 gttaaaccat tttttccgtg actatcgcgc gaataaagtc cgatcaatcg atccccgcct
    28801 gtttgaccaa ctttaccgac ttcaggggct gttagggacg cgtaaacctg tgcagctcat
    28861 ctcaggctac cgttctcttg ataccaataa tgaattacgc gcccgtagca gcggcgtagc
    28921 gaaaaaaagc taccatacaa aagggcaggc gatggatttt catattgagg gcgtggcgct
    28981 gagcaatatt cgcaaagcgg cgttatctat gcgcgcaggt ggtgtaggat attacccacg
    29041 tagtaacttt gtgcatattg ataccgggcc agcgcggcac tggtaatcag cgaggcttaa
    29101 tcaaaggagc agtatgaact atcgtattat tccggtcacc gcgttctccc agaactgttc
    29161 attaatctgg tgcgaacaaa cccggctggc ggcgctggtc gatccgggcg gcgacgcgga
    29221 aaaaattaaa caggaagtgg acgccagcgg cgtgacgttg atgcaaattt tactcacgca
    29281 tgggcatctc gatcatgtcg gcgcggcgag tgaactggcg cagcattacg gcgttcctgt
    29341 tatcggtccg gaaaaagaag atgagttctg gctgcaagga ctgccggcgc aaagccgcat
    29401 gtttggtctg gatgagtgtc agccgctgac gcctgatcgc tggctgaacg acggcgatcg
    29461 cgtcagcgtg gggaatgtga cgttacaggt gttacattgt ccgggacaca cgccgggaca
    29521 cgtggttttc tttgatgaac agtcgcaact gctgatctcc ggcgatgtga ttttcaaagg
    29581 tggcgtcggg cgcagcgatt ttcctcgcgg cgatcacacc cagttgattg acgccattaa
    29641 gcgtaaatta ttgccgcttg gcgatgatgt gacctttatt cctggccacg gcccgctctc
    29701 tacgctcgga tacgagcgtc tgcataattc cttcctgcaa gatgagatgc cggtctggta
    29761 agcagaatga aaaagcctgc aatgtgcagg cttttttatc ggtcacgcca gtcggcagct
    29821 ttttatagta ccgcgacaat ggcttcgcac agcggcgcca tattatccgg ggtcatgccc
    29881 gccacgttca cgcgaccaga agccacggca taaacgccaa actcttcacg cagacgcagc
    29941 acctgatctt tggtcagacc gctgaatgag aacatcccgt tctgcttgat aataaagctg
    30001 aagtcacggt tcgcgccttt ttcctgcaag gtattcacga acagttgacg catacgctga
    30061 atacgctggc gcatgtccgt cagttcctgt tcccagatag cgcgcagggc gtcattactc
    30121 aggatagtcg cgacgatgga cgcgccgtgc gctggtgggt tggagtagtt agcgcgaatg
    30181 gcggatttca tctggctaaa agcgcgatcc acggtttccg catcggcggc aacgagggtg
    30241 caggcgccga cgcgctcatt atataagccg aagtttttgg agtaggagct ggcgacaatg
    30301 agctctttat gcagcgcggc aaaggcgcgc agaccttccg catcttcttc caggccgcgg
    30361 gcaaagccct ggtaggcgaa atcgaatagc ggcagccacc ctttttcaac ggaaagctca
    30421 gccagaacct gccactgttc cagagtaggg tcaatgccgg ttgggttatg acagcaaccg
    30481 tggaacagaa ccacatcgcc ggcctgtgct tcgctcaggc tggcttgtag cgcttcaaaa
    30541 tccagcgagt gattttccgc atcgtagtaa gcgtactccc gaacttccag gccggcagcg
    30601 ttaaacacgc ttttgtggtt cggccagctg gggttgctca cccacacccg ttttaccgga
    30661 gtattttttg ccaaaaagtc ggcggcaatg cgtaacgcgc cggtaccgcc cggcgtttgc
    30721 gccgtgcgtg cgcgcttatc attaatcagc gcgctgcctt tgccgaacag cagttcctga
    30781 gtgcagcgag caaattccgg aatcccgtca atgccgagat agtttttcgt cgtttcattt
    30841 tccagtaaat actgctcggc ttttttaacg ctggtgagca ccggtgtttt gccggtttca
    30901 tctttatata tgccaatgcc aaggttaatt ttccctggac ggtcatcggc gcgaaacaga
    30961 tcggccaggc ccaaaatcgg gtcggcagga gcggcggtta tgttctcaaa catgacgagg
    31021 ttccattata gttacagaag ggaaatccgc tatcaggtta acggcagatt tacaaaatgc
    31081 caaccgttag cgctaaaaag cccgcctgtt tttgaaagac gcacattttc tctaagagag
    31141 ataaaaaaac aggaccgaag tcctgttttt gaggcataaa acaaaggggt ctgctgatca
    31201 gaactggtaa gtaataccga cagccgcctg atcgtcggtg ccaacgtagc tggagctgta
    31261 gtcgttttcg tccagcaggt tgaaacggta gtcaacccat acgttcatgt ttttgttgaa
    31321 gtagtaagtc gcgcccgcct gaatatattt cgccagatcg gccgagccgt cggcgccgtt
    31381 caactgctta cctttactct gcacatacga gattgccgga cgcaggccga agtcaaactg
    31441 gtactgagcg accacttcca ggttctgcgt tttgtttgcc atttccacgg tatcggtaac
    31501 cgtattttca acaatgctca tattgcgggt ttcagcatat acggcagcca ggtagacgtt
    31561 gtttgcatca tatttcgcgc caacggccca cgattctgcg cgatcgccat taccatcgcg
    31621 atcctgctga tcgttagtac gcttgctgtt gctgtacgct gcggtgacgc caaagccgtc
    31681 gaactcatat gccatggtgt aacctacgcc atcgccattc tgagagttaa tgctgtggtt
    31741 gtcctgattt ttaccctgat actggatacc gaaagagaga ccgtccacca gaccaaagaa
    31801 gtcagagtta cggtaggtca acaaaccgcc agcacggctg gtcatgtagt tatcggtata
    31861 ggcgccgccc caggtttcgc cggagaagta gggggccata tcggtatagg attcaacatc
    31921 gtaaacgata ccgtagttac gaccataatc gattgaaccc acttccgcgt atttcaaacc
    31981 cgcgaaagcc agacgtacca gattcgagtt ctgctgttcg ccttcagcgc ggtctgcttt
    32041 agtacggtat tcccactgac cgaaaccggt cagatcggtg ttaatctgcg tttccccttt
    32101 aaaaccaatc tgggcataag tctggtcggc atttttacta tcgccggtcg ttgtccatac
    32161 gtgacgaccc acggctttac cgtacagatc cagcttatta ccatctttat tataaatttc
    32221 tgctgcgttt gcggttgcag cagccagcag ggcagggatc accgctgc
//
LOCUS       DAJVKX010000041        31966 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.041, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000041 DAJVKX010000000
VERSION     DAJVKX010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 31966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31966
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.041"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..301
                     /locus_tag="OPY25_001930"
     CDS             <1..301
                     /locus_tag="OPY25_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4440 domain-containing protein"
                     /protein_id="HCS0927556.1"
                     /translation="ALIARFAVDFTMITPGGICLDYPALGAFFQAQRACRPGLVIMVE
                     HIDLVAEWPEGAALRYRERQQLPGQAETVRWSTVILKRERGRIVWRHLHETTATA"
     gene            complement(357..2924)
                     /gene="mutS"
                     /locus_tag="OPY25_001931"
     CDS             complement(357..2924)
                     /gene="mutS"
                     /locus_tag="OPY25_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCS0927557.1"
                     /translation="MNESFDKDFSNHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYD
                     DAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPA
                     TSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLS
                     EPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQ
                     FGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATR
                     RNLEITQNLAGGVENTLAAVLDCTVTPMGSRMLKRWLHMPVRNTDILRERQQTIGALQ
                     DTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPV
                     QALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHEELDEWRALADGATDYLD
                     RLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPEL
                     KEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSANALAELDVLVNLAERAWT
                     LNYTCPTFTDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKST
                     YMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANI
                     LHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEK
                     MEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLREL
                     ESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            3082..3602
                     /locus_tag="OPY25_001932"
                     /pseudo
     CDS             3082..3602
                     /locus_tag="OPY25_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461829.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
     gene            complement(3772..4428)
                     /gene="pphB"
                     /locus_tag="OPY25_001933"
     CDS             complement(3772..4428)
                     /gene="pphB"
                     /locus_tag="OPY25_001933"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HCS0927558.1"
                     /translation="MELIRYADINSVLYRHIWVVGDIHGCYSLLLTRLAQLNFSPDTD
                     LLISTGDNIDRGKENLETLRLLNTSWFISVVGNHEAMALDAFETQDGNFWYVNGGYWY
                     DSVTQKDRQEATELLLTFKQRPHIIEVKTSSKKYVIAHADYPDDSYDYGKQVDIDSVL
                     WSRDRLLSSLQGNIHPIRGADTFIFGHMIVDYTTTFANQIYIDTGSFCSGNLSFFKIK
                     "
     gene            4655..5076
                     /locus_tag="OPY25_001934"
                     /pseudo
     CDS             4655..5076
                     /locus_tag="OPY25_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_025243904.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(5149..5676)
                     /locus_tag="OPY25_001935"
     CDS             complement(5149..5676)
                     /locus_tag="OPY25_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0927559.1"
                     /translation="MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHARQNHEKGTT
                     KTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISKGLGRYDVPVFRLGRLAVDKSMQ
                     GQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
                     SFKTLYAALSASGRL"
     gene            complement(5673..5963)
                     /locus_tag="OPY25_001936"
     CDS             complement(5673..5963)
                     /locus_tag="OPY25_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCS0927560.1"
                     /translation="MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVS
                     NVLPVAQKIVDAAERVYLTERDTQMIMEILDNPPAPNEKLLAAAFALPDMKK"
     gene            complement(6233..6433)
                     /locus_tag="OPY25_001937"
                     /pseudo
     CDS             complement(6233..6433)
                     /locus_tag="OPY25_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6837..7280)
                     /gene="invH"
                     /locus_tag="OPY25_001938"
     CDS             complement(6837..7280)
                     /gene="invH"
                     /locus_tag="OPY25_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system invasion
                     lipoprotein InvH"
                     /protein_id="HCS0927561.1"
                     /translation="MKKFYSCLPVFLLIGCAQVPLPSSVSKPVQQPGAQKEQLANANS
                     IDECQSLPYVPSDLAKNKSLSNQNADNSASKNSAISSSIFCEKYKQTKEQALTFFQEH
                     PQYMRSKEDEEQLMTEFKKVLLEPGSKNLSIYQTLLAAHERLQAL"
     gene            7736..8386
                     /gene="invF"
                     /locus_tag="OPY25_001939"
     CDS             7736..8386
                     /gene="invF"
                     /locus_tag="OPY25_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system transcriptional
                     activator InvF"
                     /protein_id="HCS0927562.1"
                     /translation="MSFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRPLKIEVL
                     SKLLAFIDGAGLVDTTYAESDKWVLLSPEFRAIWQDRKRCEYWFLQQIITPSPAFNKV
                     LALLRKSESYWLVGYLLAQSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRN
                     WRMAQSLLNSVEGHENITQLAVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK"
     gene            8383..10071
                     /gene="invG"
                     /locus_tag="OPY25_001940"
     CDS             8383..10071
                     /gene="invG"
                     /locus_tag="OPY25_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system outer membrane ring
                     protein InvG"
                     /protein_id="HCS0927563.1"
                     /translation="MKTHILLARVLACAALVLVAPGYSSEKIPVTGSGFVAKDDSLRT
                     FFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIY
                     DASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVV
                     NAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGE
                     EQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTN
                     SLLVKGTAGQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDK
                     LGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTK
                     LIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEV
                     GRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPVLGKLPLIGSLFRYSSKNKSNVV
                     RVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEVIK"
     gene            10068..11186
                     /gene="invE"
                     /locus_tag="OPY25_001941"
     CDS             10068..11186
                     /gene="invE"
                     /locus_tag="OPY25_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system gatekeeper InvE"
                     /protein_id="HCS0927564.1"
                     /translation="MIPGSTSGISFSRILSRQASHQDATQHTDAQQAEIQQAAEDSSP
                     GAEVQKFVQSTDEMSAALAQFRNRRDYEKKSSNLSNSFERVLEDEALPKAKQILKLIS
                     VHGGALEDFLRQARSLFPDPSDLVLVLRELLRRKDLEEIVRKKLESLLKHVEEQTDPK
                     TLKAGINCALKARLFGKTLSLKPGLLRASYRQFIQSESHEVEIYSDWIASYGYQRRLV
                     VLDFIEGSLLTDIDANDASCSRLEFGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAF
                     NAEESSWLLLMLSLLQQPHEVDSLLADIIGLNALLLSHKEHASFLQIFYQVCKAIPSS
                     LFYEEYWQEELLMALRSMTDIAYKHEMAEQRRTIEKLS"
     gene            11211..13268
                     /gene="invA"
                     /locus_tag="OPY25_001942"
     CDS             11211..13268
                     /gene="invA"
                     /locus_tag="OPY25_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system export apparatus
                     protein InvA"
                     /protein_id="HCS0927565.1"
                     /translation="MLLSLLNSARLRPELLILVLMVMIISMFVIPLPTYLVDFLIALN
                     IVLAILVFMGSFYIDRILSFSTFPAVLLITTLFRLALSISTSRLILIEADAGEIIATF
                     GQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLK
                     AGIIDADAARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGISVGMTR
                     HGMDLSSALSTYTMLTIGDGLVAQIPALLIAISAGFIVTRVNGDSDNMGRNIMTQLLN
                     NPFVLVVTAILTISMGTLPGFPLPVFVILSVVLSVLFYFKFREAKRSAAKPKTSKGEQ
                     PLSIEEKEGSSLGLIGDLDKVSTETVPLILLVPKSRREDLEKAQLAERLRSQFFIDYG
                     VRLPEVLLRDGEGLDDNSIVLLINEIRVEQFTVYFDLMRVVNYSDEVVSFGINPTIHQ
                     QGSSQYFWVTHEEGEKLRELGYVLRNALDELYHCLAVTLARNVNEYFGIQETKHMLDQ
                     LEAKFPDLLKEVLRHATVQRISEVLQRLLSERVSVRNMKLIMEALALWAPREKDVINL
                     VEHIRGAMARYICHKFANGGELRAVMVSAEVEDVIRKGIRQTSGSTFLSLDPEASANL
                     MDLITLKLDDLLIAHKDLVLLTSVDVRRFIKKMIEGRFPDLEVLSFGEIADSKSVNVI
                     KTI"
     gene            13292..13699
                     /gene="spaK"
                     /locus_tag="OPY25_001943"
     CDS             13292..13699
                     /gene="spaK"
                     /locus_tag="OPY25_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system chaperone SpaK"
                     /protein_id="HCS0927566.1"
                     /translation="MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSIC
                     ISVKDDDVWIWAQLGADSMVVLQQRAYEILMTIMEGCHFARGGQLLLGEQNGELTLKA
                     LVHPDFLSDGEKFSTALNGFYNYLEVFSRSLMR"
     gene            13696..14991
                     /gene="invC"
                     /locus_tag="OPY25_001944"
     CDS             13696..14991
                     /gene="invC"
                     /locus_tag="OPY25_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctN family type III secretion system ATPase
                     InvC"
                     /protein_id="HCS0927567.1"
                     /translation="MKTPRLLQYLAYPQKITGPIIEAELRDVAIGELCEIRRGWHQKQ
                     VVARAQVVGLQRERTVLSLIGNAQGLSRDVVLYPTGRALSAWVGYSVLGAVLDPTGKI
                     VERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMGIFAS
                     AGCGKTMLMHMLIEQTEADVFVIGLIGERGREVTEFVDMLRASHKKEKCVLVFATSDF
                     PSVDRCNAAQLATTVAEYFRDQGKRVVLFIDSMTRYARALRDVALASGERPARRGYPA
                     SVFDNLPRLLERPGATSEGSITAFYTVLLESEEEADPMADEIRSILDGHLYLSRKLAG
                     QGHYPAIDVLKSVSRVFGQVTTPTHAEQASAVRKLMTRLEELQLFIDLGEYRPGENID
                     NDRAMQMRDSLKAWLCQPVAQYSSFDDTLSGMNAFADQN"
     gene            14969..15412
                     /gene="spaM"
                     /locus_tag="OPY25_001945"
     CDS             14969..15412
                     /gene="spaM"
                     /locus_tag="OPY25_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system protein SpaM"
                     /protein_id="HCS0927568.1"
                     /translation="MHSLTRIKVLQRRCTVFHSQCESILLRYQDEDRGLQAEEEAILE
                     QIAGLKLLLDTLRAENRQLSREEIYTLLRKQSIVRRQIKDLELQIIQIQEKRSELEKK
                     REEFQKKSKYWLRKEGNYQRWIIRQKRHYIQREIQQEEAESEEII"
     gene            15412..16422
                     /gene="spaN"
                     /locus_tag="OPY25_001946"
     CDS             15412..16422
                     /gene="spaN"
                     /locus_tag="OPY25_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system protein SpaN"
                     /protein_id="HCS0927569.1"
                     /translation="MGDVSAVSSSGNILLPQQDEVGGLSEALKKTVEKHKTEYSGDKK
                     DRDYGDAFVMHKETALPVLLAAWRHCAPAKSEHHNGNVSGLHHNGKGELRIAEKLLKV
                     TAEKSVGLISAEAKVDKSAALLSPKNRPLESVSGKKLSADLKAVESVSEVTDNATGIS
                     DDNIKALPGDNKAIAGEGVRKEGAPLARDVAPARMAAANTGKPDDKDHKKVKDVSQLP
                     LQPTTIADLSQLTGGDEKMPLAAQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSV
                     NIQARQAGEFSLIPSNTQVEHRLHDQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEED
                     DA"
     gene            16422..17333
                     /gene="spaO"
                     /locus_tag="OPY25_001947"
     CDS             16422..17333
                     /gene="spaO"
                     /locus_tag="OPY25_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system protein SpaO"
                     /protein_id="HCS0927570.1"
                     /translation="MSLRVRQIDRREWLLAQTATECQRHGREATLEYPTRQGMWVRLS
                     DAEKRWSAWIKPGGWLEHVSPALAGAAVSAGAEHLVVPWLAATERPFELPVPHLSCRR
                     LCVENPVPGSALPEGKLLHIMSDRGGLWFEHLPELPAVGGGRPKMLRWPLRFVIGSSD
                     TQRSLLGRIGIGDVLLIRTSRAEVYCYAKKLGHFNRVEGGIIVETLDIQHIEEENNTT
                     ETAETLPGLNQLPVKLEFVLYRKNVTLAELEAMGQQQLLSLPTNVELNVEIMANGVLL
                     GNGELVQMNDTLGVEIHEWLSESGNGE"
     gene            17323..17997
                     /gene="spaP"
                     /locus_tag="OPY25_001948"
     CDS             17323..17997
                     /gene="spaP"
                     /locus_tag="OPY25_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaP"
                     /protein_id="HCS0927571.1"
                     /translation="MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQ
                     QIPSNMTLNSVALLLSMFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDY
                     LIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFK
                     IGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQ
                     YMDIAT"
     gene            18023..18283
                     /gene="spaQ"
                     /locus_tag="OPY25_001949"
     CDS             18023..18283
                     /gene="spaQ"
                     /locus_tag="OPY25_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaQ"
                     /protein_id="HCS0927572.1"
                     /translation="MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQE
                     QTLPFGIKLLGVCLCLFLLSGWYGEVLLSYGRQVIFLALAKG"
     gene            18287..19078
                     /gene="spaR"
                     /locus_tag="OPY25_001950"
     CDS             18287..19078
                     /gene="spaR"
                     /locus_tag="OPY25_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaR"
                     /protein_id="HCS0927573.1"
                     /translation="MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRN
                     AIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAVGVMLGCLLSWPFWVMHALGCII
                     DNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
                     NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTV
                     KSGIAVLIMLLYFSPVLPDNVPRLSFQATGLSSWFYERGATHVLE"
     gene            19065..20135
                     /gene="spaS"
                     /locus_tag="OPY25_001951"
     CDS             19065..20135
                     /gene="spaS"
                     /locus_tag="OPY25_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaS"
                     /protein_id="HCS0927574.1"
                     /translation="MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVS
                     YGSFNEFMGIIKIIIADNFDQSMADYSLAVFGIGLKYLIPFMLLCLVCSALPALLQAG
                     FVLATEALKPNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEI
                     FSQLNGNVVDIAVIWRELLLALVLTCLACALIVLLLDAIAEYFLTMKDMKMDKEEVKR
                     EMKEQEGNPEVKSKRREVHMEILSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIP
                     MISVYETNQRALAVRAYAEKVGVPVIVDIKLARSLFKTHRRYDLVSLEEIDEVLRLLV
                     WLEEVENAGKDVIQPQENEVRH"
     gene            20273..20770
                     /gene="sicA"
                     /locus_tag="OPY25_001952"
     CDS             20273..20770
                     /gene="sicA"
                     /locus_tag="OPY25_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SycD/LcrH family type III secretion system
                     chaperone SicA"
                     /protein_id="HCS0927575.1"
                     /translation="MDYQNNVSEERVAEMIWDAVSEGATLKDVHGIPQDMMDGLYAHA
                     YEFYNQGRLDEAETFFRFLCIYDFYNPDYTMGLAAVCQLKKQFQKACDLYAVAFTLLK
                     NDYRPVFFTGQCQLLMRKAAKARQCFELVNERTEDESLRAKALVYLEALKTAETEQHS
                     EQEKE"
     gene            20773..22554
                     /gene="sipB"
                     /locus_tag="OPY25_001953"
     CDS             20773..22554
                     /gene="sipB"
                     /locus_tag="OPY25_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipB"
                     /protein_id="HCS0927576.1"
                     /translation="MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDV
                     VATKAGDLKAGTKSGESAINTVGLKPPTDAAREKLSSEGQLTLLLGKLMTLLGDVSLS
                     QLESRLAVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAA
                     AKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKA
                     KAEKADNILTKFQGTANAASQNQVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQ
                     NDLALFNALQEGRQAEMEKKSAEFQEETRKAEETNRIMGCIGKVLGALLTIVSVVAAV
                     FTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKA
                     LEGLGVDKKTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIK
                     KLVPNVLKQLAQNGSKLFTQGMQRITSGLGNVGSKMGLQTNALSKELVGNTLNKVALG
                     MEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKVT
                     AELQKAMSSAVQQNADASRFILRQSRA"
     gene            22582..23811
                     /gene="sipC"
                     /locus_tag="OPY25_001954"
     CDS             22582..23811
                     /gene="sipC"
                     /locus_tag="OPY25_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipC"
                     /protein_id="HCS0927577.1"
                     /translation="MLISNVGINPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSS
                     KVSDLGLSPTLSAPAPGVLTQTPGTITSFLKASIQNTDMNQDLNALANNVTTKANEVV
                     QTQLREQQAEVGKFFDISGMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAK
                     TTASSMMREGMNALSGSISQSALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTT
                     ESHSIKNVLNGQNSVKLGAEGVDSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESL
                     GIKNSNKQISPEHQAILSKRLESVESDIRLEQNTMDMTRIDARKMQMTGDLIMKNSVT
                     VGGIAGASRQYAATQERSEQQISQVNNRVASTASDEARESSRKSTSLIQEMLKTMESI
                     NQSKASALAAIAGNIRA"
     gene            23881..24903
                     /gene="sipD"
                     /locus_tag="OPY25_001955"
     CDS             23881..24903
                     /gene="sipD"
                     /locus_tag="OPY25_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipD"
                     /protein_id="HCS0927578.1"
                     /translation="MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTD
                     IISLSQAATKIQQAQQTLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQN
                     ENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
                     TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQ
                     TGSGMTTATKAEAEQWIKELNLPDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSA
                     LELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLVKVLSSTISSSLETA
                     KSFLQG"
     gene            24922..26979
                     /gene="sipA"
                     /locus_tag="OPY25_001956"
     CDS             24922..26979
                     /gene="sipA"
                     /locus_tag="OPY25_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector SipA"
                     /protein_id="HCS0927579.1"
                     /translation="MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATATLSG
                     EIKGQQLEDFPALIKQASLDALFKCGKDAEALKEVFTNSNNVAGKKAIMEFAGLFRSA
                     LNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL
                     DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSSLTQLVDKAAAKA
                     VEALDMCHQKLTQEQGTSVGREARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAA
                     GPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNSQRHIDNSNHDNSRK
                     TIDNSRTFIDNSQRHGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGTIDHGIAG
                     KIDVTAHATAEAVTNSSSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPLQAT
                     VHGVDDNKQQSQTAEIVNVKPLASQLAGVENVKIDTLQSDSTVITGNKAGTTDNDNSQ
                     TDKTGPFSGLKFKQNSFLSTVPSVTNMHSIHFNAREAFLGVIRKALEPDASTPFPVRR
                     AFDGLRGEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIAL
                     QFAREAGLTRQKGETDYVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLH
                     MQR"
     gene            26998..27246
                     /locus_tag="OPY25_001957"
     CDS             26998..27246
                     /locus_tag="OPY25_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCS0927580.1"
                     /translation="MNMDIEARVKKVITSCIAVDVDSINGQTHLVEDLYADSLDLIDI
                     VFGLSEEFDISCNENDLPDMTTFADICRVVKKSLESRV"
     gene            27290..27550
                     /locus_tag="OPY25_001958"
     CDS             27290..27550
                     /locus_tag="OPY25_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927581.1"
                     /translation="MKIITHVVPGSGMAAIYDDIADSSRFVIKGKLRHVENDPKELLI
                     CVPMRSEWLFYWIKGEKYCARRWARKNIKTLCNQIKFEEAIL"
     gene            27577..27969
                     /gene="sicP"
                     /locus_tag="OPY25_001959"
     CDS             27577..27969
                     /gene="sicP"
                     /locus_tag="OPY25_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone SicP"
                     /protein_id="HCS0927582.1"
                     /translation="MQAHQDIIANIGEKLGLPLTFDDNNQCLLLLDSDIFTSIEAKDD
                     IWLLNGMIIPLSPVCGDSIWRQIMVINGELAANNEGTLAYIDAAETLLFIHAITDLTN
                     IYHIISQLESFVNKQEALKNILQEYAKV"
     gene            27956..29587
                     /gene="sptP"
                     /locus_tag="OPY25_001960"
     CDS             27956..29587
                     /gene="sptP"
                     /locus_tag="OPY25_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector
                     GTPase-activating protein SptP"
                     /protein_id="HCS0927583.1"
                     /translation="MLRYDERKLNNLTLSSFSKSGVSSDTRLYIAKENTDKAYVAPEK
                     FSSKVLTWLGKMPLFKNTEVVQKHTENIRVQNQKILQTFLQALTEKYGEKAVNNALYM
                     SSINMNKPLTQRLVVQITECVKGADGGFINLIKNKDNVGVMNAALVIKGGDTKVTEQN
                     NDVGAESKQPLLDIALKGLKRTIPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQSL
                     NKIPEAKQLNDYVTTLKNIQIGADRFSQWGTCGGEVERWIDKASTHELTQAVKKIHVI
                     AKELKNVTAELEKIKAGASMPQTMSGPTLGLARFAVSSIPINQQTQVKLSDGMPVPVN
                     TLTFDGKPVALAGSCPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPAYFRG
                     SYTFGEVHTNSQKVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQ
                     LEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTMAAALVLKDNPHSNLEQV
                     RADFRNSRNNRMLEDASQFVQLKAMQAQLLMTTAS"
     gene            complement(29641..30123)
                     /gene="iagB"
                     /locus_tag="OPY25_001961"
     CDS             complement(29641..30123)
                     /gene="iagB"
                     /locus_tag="OPY25_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system invasion protein
                     IagB"
                     /protein_id="HCS0927584.1"
                     /translation="MHYFFIIVIWLLSINTAWADCWLQAEKMFNIESELLYAIAQQES
                     AMKPGAIGHNRDGSTDLGLMQINSFHMKRLKKMGISEKQLLQDPCISVIVGASILSDM
                     MKIYGFSWEAVGAYNAGTSPKRSDIRKRYAKKIWENYRKLKEMSAEEKNKRLSIAVNK
                     "
     gene            complement(30141..31802)
                     /gene="hilA"
                     /locus_tag="OPY25_001962"
     CDS             complement(30141..31802)
                     /gene="hilA"
                     /locus_tag="OPY25_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator HilA"
                     /protein_id="HCS0927585.1"
                     /translation="MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVL
                     VILLEAAGKIVSKNTLLDQVWGDAEVNEESLTRCIYALRRILSEDKEHRYIETLYGQG
                     YRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLP
                     VTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIK
                     LIEHQPASLLQNKIANLLLRCIPGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYS
                     LQQALKLLTQCVNMSPNSIAPYCALAECYLSMAQMGIFDKQNAMIKAKEHAIKATELD
                     HNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEAL
                     QTINECLKLDPTRAAAGITKLWITYYHTGIDDAIRLGDELRSQHLQDNPILLSMQVMF
                     LSLKGKHELARKLTKEISTQEITGLIAVNLLYAEYCQNSERALPTIREFLESEQRIDN
                     NPGLLPLVLVAHGEAIAEKMWNKFKNEDNIWFKRWKQDPRLIKLR"
BASE COUNT         8650 a         6831 c         8139 g         8346 t
ORIGIN      
        1 ggcgttgata gcgcgttttg ctgttgattt tacgatgata acgccaggag gtatttgtct
       61 ggattatccg gcgctgggcg cttttttcca ggcgcagcgc gcgtgtcgcc cggggctggt
      121 tatcatggtt gagcacattg atcttgtggc ggagtggccg gaaggcgccg cgctgcgtta
      181 tcgtgagcgc cagcaactgc cgggccaggc cgagacggta cgctggtcga cggtcatttt
      241 aaaaagggaa agaggacgga tagtctggcg tcatttacat gaaacgacag ccacagcctg
      301 aaaagcctgt tccggcgcgc agacccgata gcgcggcgct atcgggtctg acacgtttac
      361 accagacttt tcagccgata gatccactcc agcgcctggc gtggcgtcag ggagtccgga
      421 tcgagattct ccagcgcttc aacggcgggc gatgtctcct ccggggcggc aagcaacgac
      481 atttgcgtgc cgtccacctg cgttgccgcc gcattgggcg agatgctttc cagctcgcgg
      541 agtttttggc gcgcgcgttt gatgacttct ttagggacgc ccgcaagcgc cgcgaccgcc
      601 aggccatagc tcttacttgc cgcgccgtcc tgcacgctgt gcataaacgc gatagtatcg
      661 ccgtgttcca gcgcatccag gtggacgttc gccacgcctt ccattttctc cggtaattgg
      721 gtcagctcga agtagtgggt agcgaacagc gttaacgctt taatcttatt cgcgagattc
      781 tccgcgcagg cccaggccaa tgacagcccg tcatacgtgg aggtaccgcg cccgatttca
      841 tccatcaata ccagactgtt ttccgtcgca ttatgcagaa tgttcgcggt ttcggtcatc
      901 tccaccataa aggtcgaacg cccggaagcc aggtcgtccg ctgcgccgac gcgggtaaaa
      961 atacggtcga tggggccgat ttccacgttt tgcgccggaa cgtaactgcc gatataggcc
     1021 agcagggcga tcaatgccgt ttgtcgcata taggtacttt taccgcccat attggggccg
     1081 gtaatgatca acatccggcg ctgcggcgac agattgagcg ggttagcgat aaacggctca
     1141 ttcagtacct gttcaaccac cgggtggcga ccttcggtaa tacggatacc gggtttatcg
     1201 gtaaatgttg ggcaggtgta attcagcgtc caggcgcgtt cggccaggtt aaccagcaca
     1261 tccagctccg ccagagcgtt ggcgctctgc tgtaaatcgg ccagatgcgg caacagcaga
     1321 tcaaacaatt cgtcatatag ctgtttttcc agcgccagtg ctttgccttt cgaggtcaga
     1381 actttatctt cgtactcttt aagctcagga ataatgtagc gttcggcatt tttcagcgtc
     1441 tggcgacgca cataattgat gggcgccaga tggctttgac cacggctaat ctgaatgtaa
     1501 taaccatgta ccgcgttata gccgactttc agcgtatcca gcccggtacg ctcgcgttcg
     1561 cgaatttcca gacgatcgag ataatcggtg gcgccgtccg ccagcgcgcg ccattcatcc
     1621 agctcttcat ggtagccggg cgcaataacg ccgccgtcgc ggaccagtac cggcggcgcg
     1681 tcaataatgg cgcgctccag gaggtcgcgc agttcggcga aatcgcccat ttttttacgc
     1741 aacgcctgta ccggcgcgct gtcaacggtt tcaagctgag cgtgcaattc cggcagctgc
     1801 tggaaggcgt gacgcattcg ggcgagatcg cgcggacgcg cggtgcgcag cgccagacgc
     1861 gcaaggatgc gctccagatc gccgacctga cgcagcaccg gttgcagttc gctgacggta
     1921 tcctgcaagg cgccgatggt ctgctggcgt tcacgtaata tgtcggtatt tcgtaccggc
     1981 atatgcagcc agcgtttaag cattcggcta cccattggcg tcacggtaca gtcaagcacc
     2041 gcggcgaggg tattttcgac accgccggcc aggttctggg taatttccag attgcggcgg
     2101 gtcgcggcat ccataatgat gctgtcctgc tggcgttcca tcgtaatgga acgaatatgc
     2161 ggcagggagg tgcgctgggt atcttttacg tactgtaaca ggcagcctgc cgcacataat
     2221 ccacgcgagg cattttcgac gccgaaaccg accagatccc gcgtaccgaa ttgcagattt
     2281 aactgctggc gggcggtatc aatctcaaac tcccacaacg ggcgacggcg cagaccccgg
     2341 cgtccctcta ttaacgccat ttcagcaaaa tcttcggcat acaacagttc ggcgggattg
     2401 gtgcgctgca gctctgcggc catcgtttca cggtcggcgg gttcgctcag acgaaagcgc
     2461 ccggagctga tatccagcgt ggcgtaaccg tagcctttac catcctgcca gatagccgcc
     2521 agcaggttat cctgacgctc ctgtaacagg gcttcatcgc tgatggtgcc aggcgtaacg
     2581 atacgcacga ctttacgttc aacgggacct ttgctggtgg ccggatcgcc aatctgttcg
     2641 caaatagcga cggattcgcc ctgattgacc agtttcgcga ggtagttttc tacggcgtgg
     2701 tgcgggatac ccgccatagg gataggttcg ccagccgatg cgccgcgttt ggtcagcgaa
     2761 atatcgagca actgcgacgc acgctttgcg tcgtcataaa acagctcgta aaagtctccc
     2821 atacgataaa agagcaggat ctccggatgc tgggctttca gcttgagata ctgctgcatc
     2881 atgggggtgt ggttggagaa gtccttatca aatgactcat tcatattgat tttactcgtt
     2941 ttttattctt tcaagtgctc atgtggccat aggtaaaacc cctataaact cacataaacc
     3001 cataaatttg tagctcatct gtagcctaaa atgtgacagg ttacattctc atcattcctg
     3061 gactacaaca ggggtgatac tttgaaaaca actctcagcc agcctttcat tatcaacaag
     3121 ttaagtatca atgttaagtc tgcgctcagt cgctctggaa aaatcgtttt cgaagctaac
     3181 ccagctcaaa aactctacat tgttttcgat gaccacagac aagctcctgc tggtttcggg
     3241 gtaaaagcca gtttgacgaa aaaaacctac gtaatccagc gaagagtagc ctcgtcagat
     3301 cgtaatgtca gtgagggtag gaagccaagt tctgtcttga aagtaaaagt tgaaaatgtg
     3361 ttcgattttc caaatattga cgaaacaagg caatctgcag gcaattagtt cagaccatgt
     3421 tcgcaacaaa gagaaatcac aacaaaatta agagggaaac ggatgcttcc gaactcaaga
     3481 ccgtaatcaa gattgtgttg catgaaggca agccgatcca tttcgccacc acggttattg
     3541 tgctttattc cgataggtat cttgagctgt gcgatcttta ctcttctcag gcgatcgagt
     3601 aactacctgc gtcggattac ggcttcgttt tttggtctgc gatcttaatg atgaaatggg
     3661 cggaaaaacg cgaaatttag acgctattac gaatgagcaa tggtacttat tgaaggctat
     3721 atcattgcca taatgcaggg agggttaata ttatataatt ctatttccag actactttat
     3781 tttaaaaaaa gacagattgc ctgaacagaa agaaccggtg tcaatgtaga tttgattggc
     3841 gaatgttgtt gtgtaatcaa caatcatatg gccgaagatg aaagtatccg caccgcgtat
     3901 tggatggata ttcccctgta acgaactaag cagacgatcg cgtgaccata gaacgctatc
     3961 aatatcaact tgcttcccat aatcgtagct gtcatctgga taatcggcat gggcaatcac
     4021 gtacttcttt gaggacgttt taacctctat gatgtgagga cgctgcttaa aagttagtaa
     4081 tagctcagtg gcttcttgcc tgtctttttg ggtgaccgag tcgtaccagt aaccaccgtt
     4141 tacataccag aaattgccat cctgtgtttc aaaagcgtca agcgccatag cttcatgatt
     4201 acccactaca gaaataaacc atgaggtatt taacagtctc agtgtttcaa ggttttcttt
     4261 tcctcgatca atgttatctc cagtggagat caagagatcg gtatcaggag agaaatttaa
     4321 ttgagccagt ctggttaaca ataaggagta acatccatga atatcaccaa cgacccaaat
     4381 gtggcgatag agaacgctgt tgatgtcagc ataacgaatt aattccatga tgttcctata
     4441 gcacaatttt ggaggctggt attataacaa agaagtaggg taatattaat ttttattgtt
     4501 taaaatacac agttattaaa atagcctaca agctagaaat gaacagataa tatatatttt
     4561 atgaatcggt taattaaagt agacgatgtg cttgaaagat gcgctatttc tcgcgcaaca
     4621 ctttcctgat taattgcaaa ggcatacttt cccgctcagc ggcacgacag atgcgcaggc
     4681 actgccgggg ctgattagcc agactcaccg taaaatcagg gaagcctcgg ctgacggcgc
     4741 ttatgacacg cgctattgcc atgatgtgtt attaatcagg ccgctaatcc cgccacgaag
     4801 cggtgcgcga tactggccgg gcaagtacca tgagcgtaac cacgcggtgg cgaatcaaca
     4861 tctgagcggc agcaatgagg tctggaaaag aaagtgggct atcaccgttg ttcagtagtg
     4921 gaaacagcga tgttccgtct caaaaccttg ctgggcggcc atctgagcct gcggaactat
     4981 gacgcgcagg tgggtgaagc gatggcgatg gcgatggtca aagcgctgaa ccggatgacg
     5041 ttgttggcaa tgctgaccag cgtcaggctc gtataacgag tgctccggtg ggagtcctgt
     5101 atccttatcg ttggccgatt ctgaattatt caacaaagcc tcatgttgtc ataacctacc
     5161 agatgcagat aaagcagcat aaagcgtttt aaacgacagc aacaaggaaa ggggttgatc
     5221 gtttaatggt actgcgccaa atcctttgta ccagtcgcag acctgtttat ttttggcatc
     5281 aataagcagg gctacgccac cgacctgcaa agccgcctgt atgcaacgct ttccggcaga
     5341 taacaaaagt tgtgctccca gcccttgccc ctgcatagat ttgtctacgg ctaaacgacc
     5401 cagacgaaac actggcacat catatctccc taatcctttg ctgattgcgc cgggaacctg
     5461 tgcatatatc agtgatgcag gactgactga gtaaaagccg tggatacgtg taacatccga
     5521 attatcaagc gcaacgtagg tttttgttgt ccctttctca tgattttgtc gtgcatggcg
     5581 ttgcaggaat tggttcagat cggcatcccc acaatcaaaa ttcattcgat tgtgggtttt
     5641 ccctatcgcg gcctcatgcc agtctgtaaa catcatttct tcatgtccgg cagggcgaaa
     5701 gcagcggcaa gaagcttttc attcggcgct ggcgggttat ctaaaatttc catgatcatt
     5761 tgagtatcac gctccgtcag atatacccgt tcggcggcat caacaatctt ctgtgcgaca
     5821 ggtagtacgt tactgaccac aaaatccgtc aggttggttt gctggattgc cgcagcgcgg
     5881 actatcaact ttttggcatc cgtcgataca cgtaacgaca atctttcgtt agattctata
     5941 gctatctgag gcatggtttt catcctcctg tttatgaaca atatgtacaa ttataataca
     6001 tatctgtacg ctttcaaagc gtacatgtga ggctgatata gtccagacat ggcaagaagg
     6061 tcgttcactg tctttaaaca gggcattaac ttcggtttat cgcgattgca ttattttaat
     6121 ctcactgatt acgtatcatc agggagtttg ctaaatatat tcatgattct cttttttgcc
     6181 gtaactgctt gattgatcct acccgcgtag tatggacaca accctaagcg gcggacatct
     6241 cctgctcacg ttcagaagaa gagagctgag tttgctgttt gcttcgccag ctgtagagct
     6301 gtgatttata caggttaagc tcacgggcgg cagcgggcac cccaatgcgt tccgccagtt
     6361 tcagggcttc ctgacgaaat tcaggcgtgt gctgcttgcg tggctttttg gtggttgatg
     6421 ctggttttgt tatgtgagtc acctcttgct tgagcgttta ctcacttagt tgtgtgtcca
     6481 ctattgctgg gtaagttcaa aagaacgtta tccgcgaaaa gtggatgggg tatcgtaaga
     6541 atgccaacat gtggggcaag agggggatgt cagtttatcg cgatatacga gacgatagtt
     6601 tatcagtata agtttcggct attttcccga gtttgggagg ccgttcttta tcacaaataa
     6661 aaaaagcagc agcgaggtgc tgctgtatca aaaagcagat tgataaatgc aacgtaagag
     6721 acaaatggcc aaccgtaaaa gtgaccatag ctataataat tatattgata ttaagtggca
     6781 atgcaaagta tggtcttaat tatatcatga tgagttcagt cagcggtgat atggccttat
     6841 aaggcttgca gtctttcatg ggcagcaagt aacgtctgat atatgcttaa attcttactt
     6901 ccgggttcaa gtagaacttt tttaaattcg gtcatgagtt gctcttcatc ttctttcgaa
     6961 cgcatgtatt gtggatgttc ctggaagaag gtaagcgcct gttctttggt ttgtttatat
     7021 ttttcgcaaa aaatgcttga gctgattgcg ctattttttg atgcggaatt atcagcgttc
     7081 tggtttgata atgatttatt cttcgcaagg tctgacggca catacggaag agactgacac
     7141 tcatcaatac tatttgcgtt ggccagttgc tctttctgag cgccaggttg ctgtaccggt
     7201 ttgctcacgg aggaagggag gggcacctgg gcacagccga tcagtaaaaa gacaggaaga
     7261 cagctataaa attttttcat attaactcca actacagaag aatgaggcgc catgttttta
     7321 cacaaccgtc agaatgttat ctgacaatag tgataagggg cgaatgcgtt tcaggaatgc
     7381 tagcaaaaaa aactcctgat ataaataatt aattctccat cccgatgaca atatctgaat
     7441 ttttgctgct gtagaacaat aagccataat ttgtatacta tgagctgatt ttctatttta
     7501 aatcagcaag cgctgtgcaa gttggctaat ttaattagcg ggtggcatca gtttcataat
     7561 gattgcatca ggattttgcc acccgctcct ggtattgttt acatattaaa atgattttta
     7621 actggtgctg acaacaatgc taaatacgca ggaagtactt aaagaaggag agaagcggaa
     7681 aatccgcagc ccggaagcat ggtttataca gacgtgttcc gcgcaaaagc tgcatatgtc
     7741 attttctgaa agccgacaca atgaaaactg cctgattcag gaaggcgcgc tgcttttttg
     7801 cgagcaggcc gttgtcgcac cagtatcagg agacctggtt tttcgaccgt taaaaattga
     7861 agtactcagc aaattactgg catttatcga tggcgcagga ttagtggaca cgacatatgc
     7921 tgaatccgat aaatgggttt tgctgagtcc tgagtttcgc gctatttggc aagatcgtaa
     7981 acgctgcgag tactggtttt tgcagcaaat tattacgcct tctccggcct tcaataaggt
     8041 actggcgctg ttacgaaaaa gcgagagtta ctggttggtt ggctatttac tcgctcagtc
     8101 aaccagcggc aacacgatga gaatgctggg agaagactat ggcgtttctt atacccattt
     8161 tcgtcgtttg tgcagcagag cgttgggcgg aaaagcgaag agtgaattac gaaactggcg
     8221 tatggcgcaa tcgctgctga atagtgtaga aggccacgag aacatcaccc aattagccgt
     8281 taatcatggt tactcatcgc cttcacattt ttctagtgag atcaaagagc tgatcggcgt
     8341 ttcgccgcgg aaattatcaa atattattca attggcagac aaatgaagac acatattctt
     8401 ttggccagag tgctggcatg tgccgcgctt gttctggttg cacctggtta ttctagtgaa
     8461 aaaatacctg taacgggaag tgggtttgtt gcgaaagacg atagcctgcg gacatttttc
     8521 gatgccatgg cgctacagct aaaggagcct gtcattgtta gcaaaatggc ggcacgaaaa
     8581 aaaattacgg gcaactttga gtttcacgat cctaacgcat tactggagaa gctttcccta
     8641 caactggggc tgatttggta tttcgatggg caggctatct atatttatga cgccagtgaa
     8701 atgcgcaatg ccgtggtttc tttacgcaac gtctcactca atgagttcaa caattttcta
     8761 aaacgctcag gtttatataa caaaaattac ccgctacgtg gcgataaccg taaaggaaca
     8821 ttctatgttt cagggccacc cgtctatgtt gatatggtgg tcaacgccgc caccatgatg
     8881 gacaagcaaa acgatggtat tgagctggga cgccagaaaa taggggtgat gcgtctgaac
     8941 aataccttcg tgggcgatcg tacctacaat ctgcgcgatc agaaaatggt tattcccggt
     9001 attgctacgg ccattgaaag gttattgcag ggagaagagc aacccttagg taatattgtc
     9061 agtagcgaac ccccggcgat gccagcattt tcagcgaatg gagaaaaagg taaagcagca
     9121 aattatgccg gtggcatgag tctgcaggaa gctttaaagc aaaatgccgc ggcgggcaat
     9181 attaaaatcg tggcctatcc ggataccaac agtttgttag taaagggaac ggctgggcag
     9241 gtgcatttta tcgaaatgct ggttaaagcg ctggatgtcg ccaaacgtca cgtagaatta
     9301 tccctgtgga ttgtcgatct taataaaagc gatctggagc gtttgggcac ttcatggagc
     9361 ggcagcataa ctattgggga caaacttggc gtgtcattaa accagtcttc aataagtacc
     9421 ctcgatggca gtcgattcat cgccgcggtc aatgcgttag aagagaagaa acaggcgacg
     9481 gtggtttcgc gtccggtatt actgactcag gaaaatgttc ccgctatttt tgataacaac
     9541 agaacgtttt acaccaagct gattggggaa cgtaatgtgg cgcttgagca tgtaacatac
     9601 ggaacaatga tccgagtgct gccccgtttt tccgcagatg gtcagataga aatgtcgctg
     9661 gacattgaag atggcaacga taagacgccg caatccgata ctaccacctc cgtagatgcg
     9721 ttacccgaag tcgggcgaac gttaattagc actattgcaa gagttccgca cggaaaaagt
     9781 ttgctggtcg gtggttatac acgggatgca aataccgata ctgtccaaag tattccggtt
     9841 ttaggcaaat taccgcttat tggtagcctg ttccgttatt ccagtaagaa taaaagtaat
     9901 gttgttcgtg tgttcatgat tgaaccaaaa gaaattgtcg acccgttaac gccggatgcc
     9961 agcgaatcgg taaacaatat tctgaagcaa agcggtgcct ggagtgggga cgataagtta
    10021 cagaaatggg ttcgtgttta tctggataga ggtcaggagg taattaaatg attcctggct
    10081 caacctctgg tatttcattt tccagaatat tgtcccggca ggcatctcat caggatgcga
    10141 cccaacatac tgatgcgcaa caggcggaaa tacaacaggc cgcagaggat tcgtctccag
    10201 gggcggaagt acaaaaattt gtccagtcga cggacgaaat gtcagcggcg ctggcgcaat
    10261 ttcgtaaccg tcgcgattat gaaaaaaaat ccagtaattt atctaacagt tttgaacgcg
    10321 tgctggagga tgaggcttta ccgaaggcga agcaaatatt aaagctaatt agcgtacatg
    10381 gcggcgcgtt agaagatttt ttacgtcagg cgcgtagctt atttcctgac cccagtgatt
    10441 tagtccttgt gttacgcgaa ttgcttcgtc gtaaagacct ggaagagatc gtgcggaaaa
    10501 agctggagtc gttacttaag cacgttgaag agcaaaccga tccgaagacc ctcaaggcag
    10561 ggattaattg tgcgttgaag gcccggcttt ttgggaaaac attatcgtta aaaccaggct
    10621 tattgcgcgc cagctatcgg caatttatcc agagtgaatc acatgaagtg gagatttact
    10681 ctgactggat agccagttat ggctatcaac gtcgactggt ggtactggat tttatcgagg
    10741 gttcgctatt aaccgatatt gacgcgaatg acgccagctg ttcgcgcctg gagtttggcc
    10801 agcttttacg acgcctgacg caacttaaaa tgttgcgctc cgctgaccta ctgtttgtga
    10861 gtacattgtt gtcgtattcg tttaccaaag cgtttaatgc ggaggagtcg tcgtggctac
    10921 tactgatgct ttcgctattg caacagccac atgaagtgga ttcgctgtta gccgatatta
    10981 taggtttgaa tgcgttattg cttagtcata aagaacatgc atcctttttg cagatatttt
    11041 atcaagtatg taaagccata ccctcttcac tcttttatga agaatattgg caggaagaat
    11101 tgttaatggc gttacgtagt atgaccgata ttgcctacaa gcatgaaatg gcagaacagc
    11161 gtcgtactat tgaaaagctg tcttaattta atattaacag gatacctata gtgctgcttt
    11221 ctctacttaa cagtgctcgt ttacgacctg aattactgat tctggtacta atggtgatga
    11281 tcatttctat gttcgtcatt ccattaccta cctatctggt tgatttcctg atcgcactga
    11341 atatcgtact ggcgatattg gtgtttatgg ggtcgttcta cattgacaga atcctcagtt
    11401 tttcaacgtt tcctgcggta ctgttaatta ccacgctctt tcgtctggca ttatcgatca
    11461 gtaccagccg tcttatcttg attgaagccg atgccggtga aattatcgcc acgttcgggc
    11521 aattcgttat tggcgatagc ctggcggtgg gttttgttgt cttctctatt gtcaccgtgg
    11581 tccagtttat cgttattacc aaaggttcag aacgcgtcgc ggaagtcgcg gcccgatttt
    11641 ctctggatgg tatgcccggt aaacagatga gtattgatgc cgatttgaag gccggtatta
    11701 ttgatgcgga tgctgcgcgc gaacggcgaa gcgtactgga aagggaaagc cagctttacg
    11761 gttcctttga cggtgcgatg aagtttatca aaggtgacgc tattgccggc atcattatca
    11821 tctttgtgaa ctttattggc ggtatttcgg tggggatgac ccgccatggt atggatttgt
    11881 cctccgctct gtctacttat accatgctga ccattggtga tggtcttgtc gcccagatcc
    11941 ccgcattgtt gattgcgatt agtgccggtt ttatcgtgac tcgcgtaaat ggcgatagcg
    12001 ataatatggg gcggaatatc atgacgcagc tgttgaacaa cccatttgta ttggttgtta
    12061 cggctatttt gaccatttca atgggaactc tgccgggatt cccgctgccg gtatttgtta
    12121 ttttatcggt ggttttaagc gtactcttct attttaaatt ccgtgaagca aaacgtagcg
    12181 ccgccaaacc taaaaccagc aaaggcgagc agccgctcag tattgaggaa aaagaagggt
    12241 cgtcgttagg actgattggc gatctcgata aagtctctac agagactgta ccgttgatat
    12301 tacttgtgcc gaagagccgg cgtgaagatc tggaaaaagc tcaacttgcg gagcgcctac
    12361 gtagtcagtt ctttattgat tatggcgtgc gcctgccgga agtattgtta cgcgatggcg
    12421 agggcctgga cgataacagc atcgtattgt tgattaatga gatccgtgtt gaacaattta
    12481 cggtctattt tgatttgatg cgagtggtaa attattccga tgaagttgtt tcctttggca
    12541 ttaatccaac aatccatcag caaggtagca gtcagtattt ctgggtaacg catgaagagg
    12601 gggagaaact ccgggagctt ggctatgtgt tgcggaacgc gcttgatgag ctttaccact
    12661 gtctggcggt gacgctggcg cgcaacgtca atgaatattt cggtattcag gaaacaaaac
    12721 atatgctgga ccaactggaa gcgaaatttc ctgatttact taaagaagtg ctcagacatg
    12781 ccacggtaca acgtatatct gaagttttgc agcgtttgtt aagcgaacgt gtttccgtgc
    12841 gtaatatgaa attaattatg gaagcgctcg cattgtgggc gccaagagaa aaagatgtca
    12901 ttaaccttgt ggagcatatt cgtggagcaa tggcgcgtta tatttgtcat aaattcgcca
    12961 atggcggcga attacgagca gtaatggtat ctgctgaagt tgaggatgtt attcgcaaag
    13021 ggatccgtca gacctctggc agtaccttcc tcagccttga cccggaagcc tccgctaatt
    13081 tgatggatct cattacactt aagttggatg atttattgat tgcacataaa gatcttgtcc
    13141 tccttacgtc tgtcgatgtc cgtcgattta ttaagaaaat gattgaaggt cgttttccgg
    13201 atctggaggt tttatctttc ggtgagatag cagatagcaa gtcagtgaat gttataaaaa
    13261 caatataagg gcttaattaa ggaaaagatc tatgcaacat ttggatatcg ctgaattagt
    13321 tcgttccgca ctggaagtaa gtggttgcga tccttcatta attggaggaa tagatagcca
    13381 ttcaacaatt gttctggatt tatttgcatt gccaagtatc tgtatcagcg tcaaggacga
    13441 tgatgtatgg atctgggcgc aattgggtgc tgacagcatg gtggtattac aacagcgggc
    13501 ttatgaaatc ttaatgacca taatggaagg atgccatttt gcccgcggcg ggcaattact
    13561 actgggggag cagaatgggg agctaacgct taaagcctta gtgcatccgg attttttatc
    13621 tgacggtgaa aagttctcta ctgccttgaa tgggttttac aactatctgg aagtttttag
    13681 tcggtcgcta atgagatgaa aacacctcgt ttactgcaat atctggccta cccacaaaaa
    13741 ataaccggcc caattattga ggcggaattg cgcgatgtgg ccattggcga actgtgtgaa
    13801 atacgccgtg gctggcacca aaaacaggtt gttgcacgtg cgcaggtggt tggcttacag
    13861 cgggaacgca ccgtgctgag ccttatcggc aatgcccagg ggctgagccg cgatgtcgtg
    13921 ctttatccca ctggacgtgc gttatcggcg tgggtgggat actcagtatt aggcgcggtg
    13981 ttggatccga cagggaaaat cgttgagcgt tttacccctg aagtggcgcc gattagcgaa
    14041 gaacgcgtta ttgatgtcgc accgccgtct tacgcttcgc gcgttggcgt ccgtgaaccg
    14101 ctgattaccg gtgtgcgcgc gattgacggg ttattgacct gtggcgtagg ccagcgaatg
    14161 ggcatttttg cctccgcagg atgcggtaag accatgctga tgcatatgct gatcgagcaa
    14221 acggaggcgg atgtctttgt tatcggtctt atcggtgaac gaggccgtga ggtcactgaa
    14281 ttcgtggata tgttgcgcgc ttcgcataag aaagaaaaat gcgtgctggt ttttgccact
    14341 tccgatttcc cctcggtcga tcgctgcaat gcggcgcaac tggcgacaac cgtagcggaa
    14401 tattttcgcg accagggaaa acgggtcgtg ctttttatcg attccatgac ccgttatgcg
    14461 cgtgctttgc gagatgtggc actggcgtcg ggagagcgtc cggcccgtcg aggttatccc
    14521 gcctccgtat tcgataattt gccccgcttg ctggaacgcc ccggggcgac cagcgaggga
    14581 agcattactg ccttttatac ggtactgctg gaaagcgagg aagaggcgga cccgatggcg
    14641 gatgaaattc gctctatcct tgacggtcac ctgtatctga gcagaaagct ggccgggcag
    14701 ggacattacc cggcaatcga tgtactgaaa agcgtaagcc gcgtttttgg acaagtcacg
    14761 acgccgacac atgctgaaca ggcatctgcc gtgcgtaaat taatgacgcg tctggaagag
    14821 ctccagcttt tcattgactt gggagaatat cgtcctggcg aaaatatcga taacgatcgg
    14881 gcgatgcaga tgcgggatag cctgaaagcc tggttatgcc agccggtagc gcaatattca
    14941 tcctttgatg acacgttgag cggtatgaat gcattcgctg accagaatta aagttttaca
    15001 gcggcgctgt acggtatttc attcacagtg tgagtcaata ttacttcgct atcaggatga
    15061 ggaccgcggg ctgcaggccg aggaggaggc gatccttgaa caaatagcgg gtctgaaatt
    15121 gttattagat acgctgcgtg cagaaaacag acagctcagt cgtgaggaaa tttatacgtt
    15181 attacgtaag cagtctattg ttcgccggca gataaaagat ttagaactcc agattataca
    15241 aattcaggaa aaacggagcg agctggaaaa gaaaagggaa gagtttcaga aaaaaagtaa
    15301 atattggttg cgcaaagaag ggaactatca acgctggata attcgtcaga aaagacacta
    15361 tatccagcga gagatacagc aggaagaggc cgagtcagag gagataattt aatgggcgat
    15421 gtgtcagctg tcagttcatc cgggaacatt ttactgccgc agcaggatga ggttggcggt
    15481 ttatcagaag cattaaaaaa aacggtggaa aaacataaga cagaatattc cggtgataaa
    15541 aaagatcgcg actatggcga tgctttcgta atgcataaag aaacggcttt accggtatta
    15601 ctggcggcat ggcgacattg cgcgccagcg aaatcagaac atcacaatgg caacgtttct
    15661 ggtctgcatc ataacggaaa aggcgaactc aggattgctg aaaaactgtt gaaagtcact
    15721 gctgaaaaat ctgtcggttt gatttctgcg gaggccaaag tagataaatc cgcagcgttg
    15781 ctatcgccta aaaataggcc gttagaaagc gtaagcggta aaaaattatc tgctgattta
    15841 aaagccgtgg aatccgttag tgaagtaacc gataatgcca cgggaatctc tgacgataat
    15901 atcaaggcat tgcctgggga taataaagcc atcgcgggcg aaggcgttcg taaagagggc
    15961 gcgccgctgg cgcgggatgt cgcacctgcc cgaatggccg cagccaatac cggtaagcct
    16021 gacgataaag atcataaaaa ggttaaagat gtttctcagc ttccgctgca accaaccact
    16081 atcgccgatc ttagccaatt aaccggcggc gatgaaaaaa tgcctttagc ggcgcaatca
    16141 aagccgatga tgactatttt tcccactgcc gatggcgtga aaggagagga tagctcgctg
    16201 acttaccgtt ttcagcgctg gggaaatgac tattccgtca atattcaggc gcggcaagca
    16261 ggggagtttt cgttaatacc gtcaaatacg caggttgaac atcgtttgca tgatcaatgg
    16321 caaaacggta atccccagcg ctggcacctg acgcgagacg atcaacaaaa tccgcagcag
    16381 caacagcaca gacagcaatc tggcgaggag gatgacgcct gatgtcattg cgtgtgagac
    16441 agattgatcg tcgcgaatgg ctattggcgc aaaccgcgac agaatgccag cgccatggcc
    16501 gggaagcgac gctggaatat ccgacgcgac agggaatgtg ggttcggttg agcgatgcag
    16561 aaaaacggtg gtcggcctgg attaaacctg ggggctggct tgagcatgtc tctcccgctc
    16621 tggcgggggc ggcggtttct gccggtgctg agcacctggt cgttccctgg cttgctgcaa
    16681 cagagcgacc gtttgagttg cccgtgccgc atttgtcctg tcggcgttta tgcgtagaga
    16741 accccgtacc gggaagcgcg ctgccggaag ggaaattgtt gcacattatg agcgatcggg
    16801 gcggcctgtg gtttgagcat cttcctgaac tgcctgcagt cgggggcggc aggccgaaaa
    16861 tgctgcgttg gccgttgcgc tttgtaatcg gtagcagtga tacgcagcgt tctttgctgg
    16921 gccgaatcgg gatcggagat gtactcctga ttcgtacttc ccgtgcggaa gtttattgct
    16981 acgcgaaaaa gttaggtcat ttcaaccgtg ttgaaggggg aattattgtg gaaacgttag
    17041 atattcaaca tatcgaagaa gaaaataata caactgaaac tgcagaaact ctgcctggct
    17101 tgaatcaatt gcccgtcaaa ctggaatttg ttttgtatcg taagaacgtt accctcgccg
    17161 aactcgaagc catggggcag caacagctat tatcactgcc gaccaatgtt gaacttaacg
    17221 ttgaaattat ggcgaatggt gttttgcttg gtaatggcga actggtacag atgaatgaca
    17281 ccttaggcgt tgagatccat gaatggctga gcgagtctgg taatggggaa tgatatctca
    17341 ttaattgcct tactggcatt ttccaccctg ttgccattta ttattgcgtc aggaacctgt
    17401 ttcgttaaat tttctattgt atttgtcatg gtgcgtaacg ccctgggatt gcagcagata
    17461 ccttcaaata tgacgcttaa cagcgtcgca ttgctgcttt ctatgtttgt tatgtggcca
    17521 ataatgcatg atgcctacgt ctattttgag gacgaagatg tcacctttaa tgatatttcg
    17581 tcattaagta aacacgttga tgaaggtctg gatggttatc gcgattatct gatcaaatat
    17641 tcagatcgcg agttagttca gttttttgaa aacgcgcaac tgaagcgtca gtatggagaa
    17701 gagaccgaga cggtaaagcg tgacaaagat gaaattgaaa aaccatcaat atttgcgtta
    17761 ttacctgctt atgcgctgag cgaaataaaa agcgcgttta aaattggttt ttatctctat
    17821 ttgccctttg ttgtcgtcga cctggtggta tccagcgtgc tactggcgct ggggatgatg
    17881 atgatgagtc cggtgacgat atctacacct attaagctgg tgctttttgt cgcgcttgat
    17941 ggctggacct tactgtctaa gggattgata ttacagtata tggacattgc aacatgacat
    18001 cattacgaga cgggatagtt aaatggatga tttagtgttt gcaggtaata aggcgctcta
    18061 tcttgttttg atcctgtcag ggtggccgac gattgtcgca acgattatcg gcctcctggt
    18121 agggttattc cagacggtaa cgcaattaca ggaacagacg ctgccttttg gcattaaatt
    18181 acttggcgtg tgtttatgct tgtttttact gtctggctgg tatggcgaag ttttactctc
    18241 ttacgggcgt caggtgatat tcctggcgtt ggctaagggg taaaaaatgc tttacgcgtt
    18301 gtactttgaa attcatcacc tggttgcgtc tgcggcacta gggtttgctc gcgtagcgcc
    18361 gatttttttc ttcctgccgt ttttgaatag cggggtatta agcggcgcgc cgagaaacgc
    18421 cattatcatc ctggtggcat tgggagtatg gccgcatgca ttgaacgagg cgccgccgtt
    18481 tttatcggtg gcgatgatcc cgttagttct gcaagaagcg gcggtaggcg tcatgctggg
    18541 ctgtctgctg tcatggcctt tttgggttat gcatgcgctg ggttgtatta tcgataacca
    18601 gcgaggggca acgctaagta gcagtatcga tccggcaaac ggtattgata cctcggaaat
    18661 ggctaatttc ctgaatatgt ttgccgctgt cgtttattta caaaacggcg gtctggtcac
    18721 gatggttgac gtgttaaata aaagctatca gctatgcgat ccgatgaacg agtgcacgcc
    18781 ttcattaccg ccgctattaa cgtttattaa tcaggtggct caaaacgcct tggttctggc
    18841 cagtccggtg gtattagtgc tgttgctgtc agaagtattc ctgggtttat tgtcgcgctt
    18901 tgctccgcaa atgaacgctt ttgcgatttc actgacggta aaaagcggca ttgccgtttt
    18961 aattatgctg ctttatttct ctccggtact accggacaat gtaccgcgac tctctttcca
    19021 ggccacaggg ttaagcagtt ggttttacga gcgaggggcg acgcatgtcc tcgaataaaa
    19081 cagaaaaacc gactaaaaaa cggctggaag actccgctaa aaaaggccag tcatttaaaa
    19141 gtaaagatct cattatcgcc tgtctgacgc tgggaggaat tgcctatctg gtgtcgtatg
    19201 gctcatttaa tgagtttatg gggataatta agatcattat tgcggataat tttgatcaga
    19261 gcatggctga ttacagtttg gccgtttttg ggataggatt aaaatatctg attccattta
    19321 tgctgctctg tttagtgtgt tccgcattac cggcgttatt acaggccggt ttcgtgctgg
    19381 cgacagaagc attaaaacct aatttatcgg cgttaaaccc ggtagaaggg gcgaaaaaac
    19441 tttttagtat gcgcacggtt aaagatacgg tcaaaaccct actgtatctc tcatcctttg
    19501 tggtggccgc catcatttgc tggaagaaat ataaggttga aatcttttct cagttaaatg
    19561 gcaatgttgt ggatattgcc gtcatttggc gtgaacttct cctcgcattg gtattaactt
    19621 gccttgcttg cgcattgatt gtcttattat tggatgctat tgcggaatat ttcctgacca
    19681 tgaaagatat gaaaatggat aaggaagaag tgaagcgtga aatgaaggag caggaaggga
    19741 acccagaggt taaatctaaa agacgtgaag ttcatatgga aattctgtct gaacaggtga
    19801 aatccgatat tgaaaactca cgcctgattg ttgccaaccc cacgcatatt acgatcggga
    19861 tttattttaa acccgaattg atgccgattc cgatgatctc ggtgtatgaa acgaatcagc
    19921 gcgcactggc cgtccgcgcc tatgcggaga aggttggcgt acctgtgatc gtcgatatca
    19981 aactggcgcg cagtcttttc aaaacccatc gccgttatga tctggtgagt ctggaagaaa
    20041 ttgatgaagt tttacgtctt ctggtttggc tggaagaggt agaaaacgcg ggcaaagacg
    20101 ttattcagcc acaagaaaac gaggtacggc attgagccgc gtaaagcagt agcgatgtat
    20161 tcattgggag ttttttgaat gttcactaac caccgtcggg gtttaataac tgcatcagat
    20221 aaacgcagtc gttaagttct acaaagtcgg tgacagataa caggagtaag taatggatta
    20281 tcaaaataat gtcagcgaag aacgtgttgc ggaaatgatt tgggatgccg ttagtgaagg
    20341 cgccacgcta aaagacgttc acgggatccc tcaagatatg atggacggtt tatatgctca
    20401 tgcttatgag ttttataacc agggacgact ggatgaagct gagacattct ttcgtttctt
    20461 atgcatttat gatttttaca atcccgatta caccatggga ctggcggcgg tatgccaact
    20521 gaaaaaacaa tttcagaaag catgtgacct ttatgcagta gcgtttacgt tacttaaaaa
    20581 tgattatcgc cccgtttttt ttaccgggca gtgtcaatta ttaatgcgta aggcggcaaa
    20641 agccagacag tgttttgaac ttgtcaatga acgtactgaa gatgagtctc tgcgggcaaa
    20701 agcgttggtc tatctggagg cgctaaaaac ggcggagaca gagcagcaca gtgaacaaga
    20761 aaaggaataa ttatggtaaa tgacgcaagt agcattagcc gtagcggata tacccaaaat
    20821 ccgcgcctcg ctgaggcggc ttttgaaggc gttcgtaaga acacggactt tttaaaagcg
    20881 gcggataaag cttttaaaga tgtggtggca acgaaagcgg gcgaccttaa agccggaaca
    20941 aagtccggcg agagcgctat taatacggtg ggtctaaagc cgcctacgga cgccgcccgg
    21001 gaaaaactct ccagcgaagg gcaattgaca ttactgcttg gcaagttaat gacactactg
    21061 ggcgatgttt cgctgtctca actggagtct cgtctggcgg tatggcaggc gatgattgag
    21121 tcacaaaaag agatggggat tcaggtatcg aaagaattcc agacggctct gggagaggct
    21181 caggaggcga cggatctcta tgaagccagc atcaaaaaga cggataccgc caagagtgtt
    21241 tatgacgctg cggccaaaaa actgacgcag gcgcaaaata aattgcaatc gctggaccca
    21301 gctgaccccg gctatgcaca agctgaagcc gcggtagaac aggccggaaa agaagcgaca
    21361 gaggcgaaag aggccttaga taaggccacg gatgcgacgg ttaaagcagg cacagacgcc
    21421 aaagcgaaag ccgagaaagc ggataacatt ctgaccaaat tccagggaac ggctaatgcc
    21481 gcctctcaga atcaggtttc ccagggtgag caggataatc tgtcaaatgt cgcccgcctc
    21541 actatgctca tggccatgtt tattgagatt gtgggcaaaa atacggaaga aagcctgcaa
    21601 aacgatcttg cgcttttcaa cgccttgcag gaagggcgtc aggcggagat ggaaaagaaa
    21661 tcggctgaat tccaggaaga gacgcgcaaa gccgaggaaa cgaaccgcat tatgggatgt
    21721 atcgggaaag tcctcggcgc gctgctaacc attgtcagcg ttgtggccgc tgtttttacc
    21781 ggtggggcga gtctggcgct ggctgcggtg ggacttgcgg taatggtggc cgatgaaatt
    21841 gtgaaggcgg cgacgggggt gtcgtttatt cagcaggcgc taaacccgat tatggagcat
    21901 gtgctgaagc cgttaatgga gctgattggc aaggcgatta ccaaagcgct ggaaggatta
    21961 ggcgtcgata agaaaacggc agagatggca ggcagcattg ttggtgcgat tgtcgccgct
    22021 attgccatgg tagcggtcat tgtggtggtc gcagttgtcg ggaaaggcgc ggcggcgaaa
    22081 ctgggtaacg cgctgagcaa aatgatgggc gaaacgatta agaagttggt gcctaacgtg
    22141 ctgaaacagt tggcacaaaa cggcagcaaa ctctttaccc aggggatgca acgtattact
    22201 agcggcctgg gtaatgtggg tagcaagatg ggcctgcaaa cgaatgcctt aagtaaagag
    22261 ctggtaggta ataccctaaa taaagtggcg ttgggcatgg aagtcacgaa taccgcagcc
    22321 cagtcagccg gtggggttgc cgagggggta tttattaaaa atgccagcga ggcgcttgct
    22381 gattttatgc tcgcccgttt tgccatggat cagattcagc agtggcttaa acaatccgta
    22441 gaaatatttg gtgaaaacca gaaggtaacg gcggaactgc aaaaagccat gtcttctgcg
    22501 gtacagcaaa atgcggatgc ttcgcgtttt attctgcgcc agagtcgcgc ataaaaactg
    22561 ccaaaataaa gggagaaaaa tatgttaatt agtaatgtgg gaataaatcc cgccgcttat
    22621 ttaaataatc attctgttga gaatagttca cagacagctt cgcaatccgt tagcgctaaa
    22681 gatattctga atagtattgg tattagcagc agtaaagtca gtgacctggg gttgagtcct
    22741 acactgagcg cgcctgcgcc aggggtatta acgcaaaccc ccggaacgat cacgtccttt
    22801 ttaaaagcca gtattcaaaa taccgacatg aatcaggatt tgaatgccct ggcaaataat
    22861 gtcacgacta aagcgaatga ggttgtgcaa acccagttac gcgagcagca ggcagaagtc
    22921 ggaaagtttt ttgatattag cggaatgtct tccagtgccg ttgcgctgtt ggctgccgcg
    22981 aatacgttaa tgctgacgtt gaaccaggct gatagcaaac tgtctggtaa gttgtcatta
    23041 gtcagttttg atgcagctaa aacgacggca agctccatga tgcgcgaagg gatgaatgcg
    23101 ttgtccggta gtatttccca gagcgcgctt cagttgggga tcactggcgt gggcgccaaa
    23161 ctggaatata aggggctgca gaatgaaaga ggcgcgctta aacataatgc cgcgaagatc
    23221 gataaactga ccactgaaag ccacagtatt aaaaacgtgc tgaacgggca gaatagcgtc
    23281 aaacttggtg ctgaaggcgt cgattctctg aaatcgttaa atatgaagaa aaccggtacc
    23341 gatgcgacga aaaatcttaa tgatgcgacg cttaaatcta atgccggaac cagcgccacg
    23401 gaaagtctgg gtattaaaaa cagtaataaa caaatctccc ctgaacatca ggctattctg
    23461 tcgaaacgtc ttgagtctgt cgaatccgat attcgtcttg agcagaatac catggatatg
    23521 acccgaatcg atgcgcgcaa gatgcagatg acgggcgatc tgattatgaa gaactcagtc
    23581 acggtcggtg gtattgcagg ggcgtccagg cagtacgccg ctactcagga acgttccgag
    23641 cagcaaatta gccaggtgaa taaccgggtt gccagcaccg catcggacga agcccgtgaa
    23701 agttcacgta aatcgaccag cctgattcag gaaatgctga aaacaatgga gagcattaac
    23761 cagtcgaaag catccgcact cgctgctatc gcaggcaata ttcgcgctta atctgacaga
    23821 tcaactatac gccatcaggg ggggatttaa tcgccctcct gatggcgaac tggggatatt
    23881 atgcttaata ttcaaaatta ttccgcttct cctcatccgg ggatcgttgc cgaacggccg
    23941 cagactcctt cggcgagcga gcacgccgag attgccgtgg taccgtctac cacagaacat
    24001 cgcggcacag atatcatttc attatcgcag gcggctacta aaatccagca ggcacagcag
    24061 acgctgcagt caacgccacc gatttctgaa gagaataatg acgagcgcac gctggcgcgc
    24121 caacagttga ccagcagcct gaatgcgctg gcgaagtccg gcgtgtcatt atccgcagaa
    24181 caaaatgaga acctgcggag cacgttttct gcgccgacgt cggccttatt tagcgcttcg
    24241 cctatggcgc agccgagaac aaccatttct gatgctgaga tttgggatat ggtttcccaa
    24301 aatatatcgg cgataggtga cagctacctg ggcgtttatg aaaacgttgt cgcagtctat
    24361 accgattttt atcaggcctt cagtgatatt ctttccaaaa tgggaggctg gttatcgcct
    24421 ggtaaggatg gaaataccat taagctaaat gttgactcac ttaaaagtga aataagtagt
    24481 ttaattaata aatacactca aataaataaa aatacgattt tatttccctc gcaaactggc
    24541 agcggaatga caacagcaac gaaagcggaa gctgagcagt ggattaaaga attgaattta
    24601 ccggacagct gtctaaaggc gtctggttct ggttatgtcg tactggtgga tacggggcca
    24661 ctgagcaaaa tggttagcga tcttaatgga ataggatcgg gttcagccct tgaactggat
    24721 aacgccaaat atcaagcctg gcagtcgggt tttaaagcac aggaagaaaa tctgaaaacc
    24781 acattacaga cgctgacgca aaaatatagc aatgccaatt cattgtacga caacctggta
    24841 aaagtgctga gcagtacgat aagtagcagc ctggaaaccg ccaaaagctt cctgcaagga
    24901 taacagaaga ggatattaat aatggttaca agtgtaagaa ctcagccccc cgtcataatg
    24961 ccaggtatgc agaccgagat caaaacgcag gccacgaatc ttgcggcgaa tctttccgcg
    25021 gtcagagaaa gtgccacagc aacgctgtca ggggaaatta aaggccagca actggaagat
    25081 tttcccgcgc tgatcaaaca ggcgagtctg gatgcgttgt ttaaatgcgg gaaagacgcc
    25141 gaggcgttaa aagaagtttt taccaattca aataatgtcg ccggtaagaa agcgataatg
    25201 gagtttgccg gcctctttcg ttcagcgctc aacgccacca gtgattctcc tgaggcgaag
    25261 acgctactga tgaaggtggg ggcagagtat accgcgcaaa tcataaaaga tggcctgaaa
    25321 gaaaagtcag cttttgggcc atggctgcca gaaacaaaga aagcggaagc gaagctggaa
    25381 aacctggaaa agcagctgtt agatatcatc aaaaataaca ctggcggtga attaagtaaa
    25441 ttatcgacga atcttgttat gcaggaggtg atgccctata ttgccagctg cattgaacat
    25501 aactttggct gtacgttaga tccgttaacc cgcagcagtc ttacgcagct tgttgacaaa
    25561 gcggcggcga aggcggttga ggcgcttgat atgtgccacc aaaaattaac gcaagagcag
    25621 ggtaccagcg taggacggga agcccggcac cttgaaatgc aaacgttgat acccctgctg
    25681 ctacgtaatg tttttgcaca aattcctgca gataaactgc ctgaccctaa aattccggaa
    25741 cctgcggctg gaccagtacc tgatggtggg aaaaaagcag aacctacggg tattaatatc
    25801 aatattaata ttgatagcag taaccatagc gtggataaca gtaagcatat taacaatagc
    25861 cgaagccatg tcgataatag ccagcgccat atcgataata gcaaccatga taatagccgg
    25921 aagacgattg ataatagccg aacatttatt gataacagcc aacgccatgg cgagtcacac
    25981 cattcgacta acagcagcaa cgtaagtcat agtcattcgc gtgtggattc gactacgcat
    26041 caaacggaga ccgcacacag cgccagcaca gggacaattg accatggcat cgcgggtaaa
    26101 attgacgtca cggctcatgc gacggcagag gctgtgacca actcttcatc cgaaagtaaa
    26161 gatggaaagg tggtcacgtc agaaaagggc actacgggtg aaacaacctc ttttgatgaa
    26221 gtcgatggcg taaccagcaa gagcattatc ggcaagccgt tacaggccac ggtgcacggc
    26281 gttgatgata ataaacagca aagccagacg gcagagattg tgaatgtgaa gccgcttgcc
    26341 agtcaactgg ctggcgtcga gaatgttaaa atcgatacct tacaatcaga ctcgacggta
    26401 attacaggta ataaagccgg tacgaccgat aatgataata gccagacaga taagactggc
    26461 ccattttctg gtttgaagtt taagcaaaat agtttcctct caacagtacc gagcgttacg
    26521 aatatgcatt caatacattt caacgcccgt gaggcgtttt tgggtgtgat acgtaaagcc
    26581 ctggagccgg atgcctctac accgtttcct gtacgcagag cgtttgacgg cttgcgtggg
    26641 gaaatattac ccaatgacac gataaagagt gcagcgttga aagcgcaatg tagcgatatt
    26701 gacaagcacc cagaattgaa agcgaaaatg gagacgctca aagaggtcat tactcatcat
    26761 ccacaaaaag aaaaactggc tgagattgca ttgcagtttg ccagagaggc ggggttgacc
    26821 aggcaaaaag gggaaactga ctatgtgtta agtaatgtgc tggacggcct tatcggagac
    26881 ggtagctggc gagctggccc ggcttacgag tcatacctga ataaacctgg tgtggatcgg
    26941 gttattacta ccgttgatgg cttgcacatg cagcgttaat taactgggaa agatgcgatg
    27001 aatatggata ttgaagcaag agtcaaaaaa gtgatcacct cctgtattgc cgttgatgtt
    27061 gatagtatca atggtcagac ccatctggtt gaggatcttt acgctgactc attggattta
    27121 attgatattg tatttggtct tagtgaggag tttgacatta gttgtaatga aaacgatctt
    27181 cctgatatga cgacctttgc ggatatatgc cgtgttgtta aaaaaagtct tgagtccagg
    27241 gtgtagtatt tttctctcgc tcgacaacaa ttgaacaaga ttaattgtta tgaaaatcat
    27301 cacacatgta gtacccggtt caggcatggc tgcaatatat gatgatattg ctgacagttc
    27361 gcgttttgtt attaaaggca agttacgtca tgttgaaaat gatccgaagg aactgctgat
    27421 ttgtgttccg atgcgtagtg aatggctatt ctactggatt aaaggagaga aatattgcgc
    27481 tcggcgatgg gcgcgaaaaa atatcaagac attgtgtaac cagattaaat ttgaagaagc
    27541 aatcttgtaa aagatataat taaagaggaa agtaaattgc aagcacacca ggatattatc
    27601 gctaatattg gtgagaaatt gggtttaccg ctcacttttg atgacaacaa tcagtgctta
    27661 ttactactcg atagcgatat ttttacgtct attgaagcta aagatgatat ctggttattg
    27721 aacggtatga ttataccgct atcgcctgtt tgtggcgatt ctatctggcg gcagattatg
    27781 gtgattaatg gtgaactggc tgcgaataat gaaggtacgt tagcgtatat tgatgccgca
    27841 gagacgttgt tgtttataca tgcaattacc gatctgacaa atatttatca tatcatatcg
    27901 cagcttgagt catttgtgaa taagcaggaa gcgctcaaaa acatactaca ggaatatgct
    27961 aaggtatgat gagaggaagt tgaataattt aacattgtct tcattttcaa aatctggcgt
    28021 gtcgagtgat acccggctat atattgctaa ggaaaatact gataaggcat atgttgcgcc
    28081 tgaaaaattt tcgtcaaaag tattaacctg gcttggaaaa atgcccttat ttaaaaacac
    28141 tgaagtggtg caaaaacaca cggaaaatat cagagtacag aaccaaaaga ttttacagac
    28201 atttctccag gcattaacgg aaaaatatgg ggaaaaagcg gtcaataatg ctttgtacat
    28261 gtccagtata aatatgaaca aaccccttac ccaacgttta gtagtgcaga tcacggagtg
    28321 tgtaaaaggt gctgacggag ggtttataaa tcttattaag aacaaggata atgttggtgt
    28381 catgaatgcc gctttagtca taaaaggcgg cgatacaaaa gtgacagaac aaaataacga
    28441 tgttggtgca gaaagtaagc aacctttact cgatatcgcg ctaaagggac ttaagagaac
    28501 aataccgcaa ctggaacaaa tggatggaaa tagcctgcga gaaaacttcc aggagatggc
    28561 ttcaggtaac ggcccgctgc gttcattaat gacgaattta cagagtttaa ataaaattcc
    28621 agaggctaaa caacttaatg attatgttac aacgttaaaa aatattcaga taggagcaga
    28681 caggttctca caatggggaa cctgtggggg agaggttgag aggtggattg ataaagcctc
    28741 tactcatgaa ttaacccaag cggtaaaaaa aattcacgtt attgctaaag aactgaaaaa
    28801 cgttacagct gaacttgaga aaataaaagc cggtgcgtca atgccacaga cgatgagcgg
    28861 accgacactg ggcctggcac ggtttgcggt cagcagcatt cccattaatc agcaaaccca
    28921 ggtgaaactg agcgatggaa tgcctgtgcc agtgaatacg ttaacttttg acggtaagcc
    28981 tgtggcatta gccggttcgt gcccaaaaaa tacgccggat gcgctggaag cgcatatgaa
    29041 aatgcttctt gaaaaagaat gttcgtgcct ggtggtgtta acgtcggaag atcagatgca
    29101 ggcaaaacaa ttaccagcct atttcagagg gagctacacc tttggcgagg tgcataccaa
    29161 cagccaaaaa gtgagctcag ccagtcaggg aggagcgata gaccaataca atatgcaact
    29221 gtcctgcggg gaaaagcggt atacaatccc ggtattgcat gtgaaaaatt ggccagatca
    29281 ccagccgtta ccgtctactg atcagttaga atacctggcg gatagggtga aaaatagtaa
    29341 ccaaaatggc gcgccggggc gtagttcatc agataagcat ttaccgatga ttcattgtct
    29401 gggcggagtg ggaagaaccg gaacgatggc ggcggctctt gtacttaagg ataatcctca
    29461 tagtaatctg gagcaggtac gtgcagattt ccggaattca cggaacaata gaatgctgga
    29521 agacgcctca cagtttgtac aactaaaagc aatgcaagcc cagttgctta tgacgacggc
    29581 aagctgataa aaacatagct tacttttaga attatctgaa agtaagctat tcctgtataa
    29641 ttatttgttt accgcgatag aaagtctttt gtttttctct tctgctgaca tctcttttaa
    29701 ttttctgtaa ttctcccaaa tttttttagc ataacgtttc cttatatccg atcgtttcgg
    29761 cgacgtcccg gcattataag cgccaacggc ctcccagcta aaaccgtaga ttttcatcat
    29821 atctgataaa atggatgcgc ccacaatgac agaaatgcag ggatcctgta acaactgttt
    29881 ttcactaatc cccatttttt tcagcctttt catatggaag ctgttaattt gcatcaggcc
    29941 aagatcggtt gaaccatctc ggttatgacc aatggcgcca ggtttcatcg ccgattcctg
    30001 ctgggcgata gcgtaaagta gttcggattc aatattgaac attttttcag cctgaagcca
    30061 gcaatcagcc catgccgtat ttatgctaag caaccagatt acgatgataa aaaaataatg
    30121 catatctcct ctctcagatt ttaccgtaat ttaatcaagc ggggatcctg tttccatctt
    30181 ttgaaccaaa tattgtcttc gtttttaaat ttattccaca ttttctcggc aatagcttcg
    30241 ccgtgggcaa ccagcactaa cggtaataat cccggattat tatctatacg ctgttcactt
    30301 tccagaaatt ctcttatcgt cggtaaggca cgctcactat tctgacaata ttcagcgtaa
    30361 agaagattaa cagcaataag tcctgttatt tcctgcgtgg atatttcttt agttaatttt
    30421 cgtgccagtt catgtttacc tttaagcgaa agaaacataa cctgcatact taataatatt
    30481 ggattatcct gcaggtgttg tgagcgtaat tcatcgccta aacgtatagc atcatcaata
    30541 ccggtatgat aataggtaat ccacagctta gtgatccctg cggctgcgcg cgttgggtcc
    30601 aattttaaac actcgttaat cgtttgtaag gcctcctcca actgaccagc catgaaaaga
    30661 ttccagccat aataatattt aatatctgca gaaatgggcg aaagtaagtt agcttgtttg
    30721 aatagcaaac tcccgacgat gtattctgag tgaatcgtat taattagccc cagtaatcct
    30781 aaagcttgtg gattattgtg gtccagctct gtcgccttaa tcgcatgttc tttagctttg
    30841 atcattgcgt tttgtttatc aaaaatcccc atttgcgcca tgctgaggta gcattctgcc
    30901 agcgcacagt aaggcgcaat gctgtttggc gacatattaa cgcattgagt cagcaattta
    30961 agcgcttgct gtaagctata gggggtgtat tgatttaact catgcttacc gcgtaagtag
    31021 accatggtac tgtcaatcga atttagctcg ctaatttgct ttgtgtccca gcgaagtccg
    31081 ggaatacatc tgagcaaaag attcgcaatt ttgttttgca agagagaagc gggttggtgt
    31141 tctatcaact taatgctttc ctggtgcagc aggtgataac ctttaacccg aactatctcg
    31201 atctgtacaa tattatcatt accatcgggt atcatctgcc cggagatata ataatcgggg
    31261 cgtaattgat ccatgagctc aagaatatcc ttaacactgc ggcagttctt cgtaatggtc
    31321 accggcagca cgctcaggcc aaagggcgca tactgcgata atcccttcac gatagagtaa
    31381 tgcagactct cggattgaac ctgatcctgc atctgaaaag gaagtatcgc caatgtatga
    31441 gtcgtaggtt gcggcgctgg cggagacacc actacgaccg gacgattaaa ccgataaccc
    31501 tgtccgtaca gtgtttcaat gtaacgatgc tctttatctt ccgacagaat acgtcgtaag
    31561 gcatagatac agcgggtaag agattcttcg ttaacttccg cgtcgcccca tacttggtcc
    31621 aataaggtgt ttttactcac aatcttgccg gcggcttcga gcaggatgac cagaacggca
    31681 tattcttttg gcggaatatt gactttcttt tctgagcgta gcagggagcc gtccatgttg
    31741 agtatgaaat catcaaagac gaatttttta ttcgatacag gaacaggatt aaaatgtggc
    31801 atgataatag tgtattctct tacagggtga aaagttataa tagctaatac aagtcgttag
    31861 gatagaatct actgtttcag taattctgct gctagtacta acggtcaggt tgagctttta
    31921 ttatgagctt aatgtcatat tgtacgggct cgggtttata tgtttt
//
LOCUS       DAJVKX010000042        31468 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000042 DAJVKX010000000
VERSION     DAJVKX010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 31468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31468
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.042"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(258..344)
                     /locus_tag="OPY25_001963"
     tRNA            complement(258..344)
                     /locus_tag="OPY25_001963"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(308..310),aa:Leu,seq:taa)
     gene            complement(356..429)
                     /locus_tag="OPY25_001964"
     tRNA            complement(356..429)
                     /locus_tag="OPY25_001964"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Cys,seq:gca)
     gene            complement(482..557)
                     /locus_tag="OPY25_001965"
     tRNA            complement(482..557)
                     /locus_tag="OPY25_001965"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(522..524),aa:Gly,seq:gcc)
     gene            complement(709..1257)
                     /gene="pgsA"
                     /locus_tag="OPY25_001966"
     CDS             complement(709..1257)
                     /gene="pgsA"
                     /locus_tag="OPY25_001966"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCS0927586.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVVVFYLPFAWAPMVSALIFCIAAI
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARGDLLDQ"
     gene            complement(1314..3146)
                     /gene="uvrC"
                     /locus_tag="OPY25_001967"
     CDS             complement(1314..3146)
                     /gene="uvrC"
                     /locus_tag="OPY25_001967"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCS0927587.1"
                     /translation="MSEIFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQHIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVAGLVSEEEYTQQVEYVRLFLSGKDDQVLTQLIARMEKAS
                     QDLAFEEAARIRDQIQAVRRVTEKQFVSNAGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRRIHVQTKPRGDRARYLKLARTNAATALVTKLSQQSTITQRLTALATVLKLPAI
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIAGITPGDDYAAMNQVLRRRY
                     GKAIEESKIPDVILIDGGKGQLAQAKAVFAELDVPWDKHRPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(3143..3799)
                     /gene="uvrY"
                     /locus_tag="OPY25_001968"
     CDS             complement(3143..3799)
                     /gene="uvrY"
                     /locus_tag="OPY25_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HCS0927588.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEACCGEDAVKWCR
                     TNAVDVVLMDMNMPGIGGLEATRKIARSTADIKVIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPAKTETPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLTSQ
                     "
     gene            4111..4266
                     /locus_tag="OPY25_001969"
     CDS             4111..4266
                     /locus_tag="OPY25_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927589.1"
                     /translation="MHHAATFILWVTPLLFDQKTTTAIFSVAYGILRRLNICYRTFSL
                     KHNEENK"
     gene            4263..4487
                     /locus_tag="OPY25_001970"
     CDS             4263..4487
                     /locus_tag="OPY25_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HCS0927590.1"
                     /translation="MSTPDFSTAENNQELATEVNCLKAMLTLMLQAMGQADAGRVILK
                     MEKQIAQMDDEAQAAVFSSTVKQIKQAYRQ"
     gene            complement(4554..5276)
                     /gene="sdiA"
                     /locus_tag="OPY25_001971"
     CDS             complement(4554..5276)
                     /gene="sdiA"
                     /locus_tag="OPY25_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HCS0927591.1"
                     /translation="MQENDFFTWRRAMLLRFQEMAAAEDVYTELQYQTQRLEFDYYAL
                     CVRHPVPFTRPKISLRTTYPQAWVTHYQSENYFAIDPVLKPENFRQGHLHWDDVLFHE
                     AQAMWDAAQRFGLRRGVTQCVMLPNRALGFLSFSRSSLRCSSFTYDEVELRLQLLARE
                     SLSALTRLEDDMVMAPEMRFSKREKEILKWTAEGKTSSEIAIILSISENTVNFHQKNM
                     QKKFNAPNKTQIACYAAATGLI"
     gene            complement(5509..6261)
                     /gene="yecC"
                     /locus_tag="OPY25_001972"
     CDS             complement(5509..6261)
                     /gene="yecC"
                     /locus_tag="OPY25_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HCS0927592.1"
                     /translation="MSAIEVTNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRCINLLEQPEAGTIKVGDIIIDTARPFSQQKGLIRQLRQHVGFVFQSFNLFPHRTV
                     LENIIEGPVIVKGEPKAEATALARELLAKVGLAGKETRYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMGFARDVADRAIFMD
                     QGQIVEQGPAKTLFADPQHPRTRQFLEKFLVK"
     gene            complement(6258..6926)
                     /gene="tcyL"
                     /locus_tag="OPY25_001973"
     CDS             complement(6258..6926)
                     /gene="tcyL"
                     /locus_tag="OPY25_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HCS0927593.1"
                     /translation="MQESIQLVIESLPYLLKGAVFTLQLSIGGMFFGLLLGFVLALMR
                     MSPLWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPAAMIGLSLNTAAY
                     TSETLRAAISAIDKGQWEAAASIGMTPWQTLRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWVMATVLSALQNYFENQLNRQE
                     REPK"
     gene            complement(6947..7933)
                     /gene="dcyD"
                     /locus_tag="OPY25_001974"
     CDS             complement(6947..7933)
                     /gene="dcyD"
                     /locus_tag="OPY25_001974"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HCS0927594.1"
                     /translation="MPLHHLTRFPRLELIGAPTPLEYLPRLSDYLGREIYIKRDDVTP
                     IAMGGNKLRKLEFLVADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPDAQLQTLATRIEAQGFRPYVIPVGG
                     SSALGAMGYVESALEIVQQCEEVVGLSSVVVASGSAGTHAGLAVGLEHLMPDVELIGV
                     TVSRSVAEQKPKVIALQQAIAGQLALTATADIHLWDDYFAPGYGVPNDAGMEAVKLLA
                     NLEGVLLDPVYTGKAMAGLIDGISQKRFNDDGPILFIHTGGAPALFAYHPHV"
     gene            complement(8087..8887)
                     /gene="tcyJ"
                     /locus_tag="OPY25_001975"
     CDS             complement(8087..8887)
                     /gene="tcyJ"
                     /locus_tag="OPY25_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HCS0927595.1"
                     /translation="MKLALLGRQALMGVMAVALVAGMSAKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVDFAEALAKHLGVKASLKPTKWDGMLASLDSKRID
                     VVINQVTISDVRKKKYDFSTPYTVSGVQALVKKGNEGTIKTAADLQGKKVGVGLGTNY
                     EEWLRQHVQGVDIRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTKGTLAVTGDA
                     FSRQESGVALRKGNEDLLKAVDNAIAEMQKDGTLKALSEKWFGADVTQ"
     gene            complement(9034..9585)
                     /gene="fliZ"
                     /locus_tag="OPY25_001976"
     CDS             complement(9034..9585)
                     /gene="fliZ"
                     /locus_tag="OPY25_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HCS0927596.1"
                     /translation="MTVQQPKRRPLSRYLKDFKHSQTHCAHCHKLLDRITLVRRGKIV
                     NKIAISQLDMLLDDAAWQREQKEWVALCRFCGDLHCKKQSDFFDIIGFKQYLFEQTEM
                     SHGTVREYVVRLRRLGNYLSEQNISHDLLQDGFLDESLAPWLPETSTNNYRIALRKYQ
                     QYKAHQQIAPRQKSPFTASSDIY"
     gene            complement(9644..10363)
                     /locus_tag="OPY25_001977"
     CDS             complement(9644..10363)
                     /locus_tag="OPY25_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HCS0927597.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVDRYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AMGQLEQELGRNATETEVAERLGIPVAEYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TEEHQQENPLHQLLEGDLRQRVMDAIESLPEREQLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            complement(10560..11764)
                     /gene="fliB"
                     /locus_tag="OPY25_001978"
                     /pseudo
     CDS             complement(10560..11764)
                     /gene="fliB"
                     /locus_tag="OPY25_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin lysine-N-methylase"
     gene            complement(11843..13363)
                     /locus_tag="OPY25_001979"
     CDS             complement(11843..13363)
                     /locus_tag="OPY25_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliC/FljB family flagellin"
                     /protein_id="HCS0927598.1"
                     /translation="MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDD
                     AAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANG
                     TNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDL
                     KEISSKTLGLDKLNVQDAYTPKETAVTVDKTTYKNGTDPITAQSNTDIQTAIGGGATG
                     VTGADIKFKDGQYYLDVKGGASAGVYKATYDETTKKVNIDTTDKTPLATAEATAIRGT
                     ATITHNQIAEVTKEGVDTTTVAAQLAAAGVTGADKDNTSLVKLSFEDKNGKVIDGGYA
                     VKMGDDFYAATYDEKTGAITAKTTTYTDGTGVAQTGAVKFGGANGKSEVVTATDGKTY
                     LASDLDKHNFRTGGELKEVNTDKTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITN
                     LGNTVNNLSSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR"
     gene            13620..15023
                     /gene="fliD"
                     /locus_tag="OPY25_001980"
     CDS             13620..15023
                     /gene="fliD"
                     /locus_tag="OPY25_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HCS0927599.1"
                     /translation="MASISSLGVGSNLPLDQLLTDLTKNEKGRLTPITKQQSANSAKL
                     TAYGTLKSALEKFQTANTALNKADLFKSTVASSTTEDLKVSTTAGAAAGTYKISVTQL
                     AAAQSLATKTTFATTKEQLGDTSVTSRTIKIEQPGRKEPLEIKLDKGDTSMEAIRDAI
                     NDADSGIAASIVKVKENEFQLVLTANSGTDNTMKITVEGDTKLNDLLAYDSTTNTGNM
                     QELVKAENAKLNVNGIDIERQSNTVTDAPQGITLTLTKKVTDATVTVTKDDTKAKEAI
                     KSWVDAYNSLVDTFSSLTKYTAVEPGEEASDKNGALLGDSVVRAIQTGIRAQFANSGS
                     NSAFKTMAEIGITQDGTSGKLKIDDDKLTKVLKDNTAAARELLVGDGKETGITTKIAT
                     EVKSYLADDGIIDNAQDNVNATLKSLTKQYLSVSNSIDETVARYKAQFTQLDTMMSKL
                     NNTSSYLTQQFTAMNKS"
     gene            15038..15445
                     /gene="fliS"
                     /locus_tag="OPY25_001981"
     CDS             15038..15445
                     /gene="fliS"
                     /locus_tag="OPY25_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HCS0927600.1"
                     /translation="MYTASGIKAYAQVSVESAVMSASPHQLIEMLFDGANSALVRARL
                     FLEQGDVVAKGEALSKAINIIDNGLKAGLDQEKGGEIATNLSELYDYMIRRLLQANLR
                     NDAQAIEEVERLLSNIAEAWKQISPKASFQESR"
     gene            15445..15813
                     /gene="fliT"
                     /locus_tag="OPY25_001982"
     CDS             15445..15813
                     /gene="fliT"
                     /locus_tag="OPY25_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HCS0927601.1"
                     /translation="MTSTVEFINRWQRIALLSQSLLELAQRGEWDLLLQQEVSYLQSI
                     ETVMEKQTPPGITRSIQDMVAGYIKQTLDNEQLLKGLLQQRLDELSSLIGQSTRQKSL
                     NNAYGRLSGMLLVPDAPGAS"
     gene            15885..17369
                     /gene="amyA"
                     /locus_tag="OPY25_001983"
     CDS             15885..17369
                     /gene="amyA"
                     /locus_tag="OPY25_001983"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HCS0927602.1"
                     /translation="MKNPTLLQYFHWYYPDGGKLWSELAERADGLNDIGINMVWLPPA
                     CKGASGGYSVGYDSYDLFDLGEFDQKGTIATKYGDKRQLLTAIDALKKNNIAVLLDVV
                     VNHKMGADEKERIRVQRVNQDDRTQIDDNIIECEGWTRYTFPARAGQYSNFIWDYHCF
                     SGIDHIENPDEDGIFKIVNDYTGDGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTHCDGFRLDAVKHIPAWFYKEWIEHVQAVAPKPLFIVAEYWSHEVDKLQT
                     YIDQADGKTMLFDAPLQMKFHEASRQGAEYDMRHIFTGTLVEADPFHAVTLVANHDTQ
                     LLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGASYEDNGENGETCRVDMPVI
                     NQLDRLILARQRFAHGIQTLFFDHPNCIAFSRSGTEENPGCVVVLSNGDDGEKTLLLG
                     DNYANKTWRDFLGNRSEHVVTNDQGEATFFCNAGSVSVWVIEDV"
     gene            complement(17409..17822)
                     /locus_tag="OPY25_001984"
     CDS             complement(17409..17822)
                     /locus_tag="OPY25_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0927603.1"
                     /translation="MKKVAIVGALLVLAGCAEVENYNDVVKTPAPAGLEGYWQSKGPQ
                     RKLVSPEAIASLVVTKEGDTLDCRQWQRVIALPGKLTMLSDDLTNVTVKRELYEIERD
                     GNTLEYDGMTLQRVARPTPECAAALEKTPLPTPLP"
     gene            18078..19283
                     /gene="yedE"
                     /locus_tag="OPY25_001985"
     CDS             18078..19283
                     /gene="yedE"
                     /locus_tag="OPY25_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016156840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HCS0927604.1"
                     /translation="MSWQHFKQTWLIKFWAPAPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQILQLFGVHAEQWGYYKLIHLEGTPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIVQAVVGGMIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFALATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFIGMIGWALLTAMHQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDLWISGRAHMAKAIIFGMAVSAIGIFSYV
                     QLGVAPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEVQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATSWDKVNLLNTFGPLGGLLVTYLLLFTALMLIIGWEKRFFRRA
                     GLTPAKESV"
     gene            19280..19513
                     /gene="yedF"
                     /locus_tag="OPY25_001986"
     CDS             19280..19513
                     /gene="yedF"
                     /locus_tag="OPY25_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HCS0927605.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            19778..20164
                     /locus_tag="OPY25_001987"
     CDS             19778..20164
                     /locus_tag="OPY25_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927606.1"
                     /translation="MIYLCTAEAKKMIKIIFISIIGVVCLAAARYSPVTVVNAHPSAI
                     ARCLADNLSPYGYILDLHETDIPGISKEFTVYYRNGAYIAGTFWIANSMTIASELIVG
                     MNGVSKQAYPIFNKSLQQCATRLSIK"
     gene            complement(20284..20598)
                     /gene="fliE"
                     /locus_tag="OPY25_001988"
     CDS             complement(20284..20598)
                     /gene="fliE"
                     /locus_tag="OPY25_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HCS0927607.1"
                     /translation="MAAIQGIEGGISQLQATAMAANGQETHSQSTVSFAGQLHAALDR
                     ISDRQTAARVQAEKFTLGEPGIALNDVMADMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            20815..22497
                     /gene="fliF"
                     /locus_tag="OPY25_001989"
     CDS             20815..22497
                     /gene="fliF"
                     /locus_tag="OPY25_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HCS0927608.1"
                     /translation="MSATASTATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVL
                     WAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQ
                     QGLPKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMP
                     KPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGH
                     LLTQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSPIVGNGNVHAQVTAQLDFANKE
                     QTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGALSNQPAPPNEAPIATPPTN
                     QQNAQNTPQTSTSTNSNNAGPRNTQRNETSNYEVDRTIRHTKMNVGDIERLSVAVVVN
                     YKTLADGKPLPLTADQMKQIEDLTREAMGFSDKRGDTLNVVNSPFSAVDNTGGELPFW
                     QQQSFIDQLLAAGRWLLVLVVAWILWRKAVHPQLTRRVEEAKAAQEQAQVRQETEEAV
                     EVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWMSNDHE"
     gene            22490..23485
                     /gene="fliG"
                     /locus_tag="OPY25_001990"
     CDS             22490..23485
                     /gene="fliG"
                     /locus_tag="OPY25_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HCS0927609.1"
                     /translation="MSNLSGTDKSVILLMTIGEDRAAEVFKHLSTREVQALSTAMANV
                     RQISNKQLTDVLSEFEQEAEQFAALNINANEYLRSVLVKALGEERASSLLEDILETRD
                     TTSGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRSQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEPPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            23478..24185
                     /gene="fliH"
                     /locus_tag="OPY25_001991"
     CDS             23478..24185
                     /gene="fliH"
                     /locus_tag="OPY25_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HCS0927610.1"
                     /translation="MSNELPWQVWTPDDLAPPPETFVPVEADNVTLTDDTPEPELTAE
                     QQLEQELAQLKIQAHEQGYNAGLAEGRQKGHAQGYQEGLAQGLEQGQAQAQTQQAPIH
                     ARMQQLVSEFQNTLDALDSVIASRLMQMALEAARQVIGQTPAVDNSALIKQIQQLLQQ
                     EPLFSGKPQLRVHPDDLQRVEEMLGATLSLHGWRLRGDPTLHHGGCKVSADEGDLDAS
                     VATRWQELCRLAAPGVL"
     gene            24185..25555
                     /gene="fliI"
                     /locus_tag="OPY25_001992"
     CDS             24185..25555
                     /gene="fliI"
                     /locus_tag="OPY25_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HCS0927611.1"
                     /translation="MTTRLTRWLTALDNFEAKMALLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCIIERQDGPETKEVESEVVGFNGQRLFLMPLEEVEGILPGARVYARNGHGD
                     GLQSGKQLPLGPALLGRVLDGGGKPLDGLPAPDTLETGALITPPFNPLQRTPIEHVLE
                     TGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGPDGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGIHGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALITEQHYARVRLFK
                     QLLSSFQRNRDLISVGAYAKGSDPMLDKAITLWPQLEAFLQQGIFERADWEDSLQALD
                     LIFPTV"
     gene            25577..26020
                     /gene="fliJ"
                     /locus_tag="OPY25_001993"
     CDS             25577..26020
                     /gene="fliJ"
                     /locus_tag="OPY25_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HCS0927612.1"
                     /translation="MAQHGALETLKDLAEKEVDDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRSNLNTDMGNGIASNRWINYQQFIQTLEKAIEQHRLQLTQWTQKVDLALKSWR
                     EKKQRLQAWQTLQDRQTAAALLAENRMDQKKMDEFAQRAAMRKPE"
     gene            26017..27246
                     /gene="fliK"
                     /locus_tag="OPY25_001994"
     CDS             26017..27246
                     /gene="fliK"
                     /locus_tag="OPY25_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HCS0927613.1"
                     /translation="MITLPQLITTDTDMTAGLTSGKTTGSAEDFLALLAGALGADGAQ
                     GKDARITLADLQAAGGKLSKELLAQHGEPGQAVKLADLLAQKANATDETLTNLTQAQH
                     LLSTLTPSLKTSALAALSKTAQHDEKTPALSDEDLASLSALFAMLPGQPVATPVAGET
                     PAENHIALPSLLRGDMLSAPQEETHTLSFSEHEKGKTEASLARASDDRAMGPSLTPLV
                     VAAAATSAKVEVEVDSPSAPVTHGAAMPTLSSATAQPQPLPVASAPVLSAPLGSHEWQ
                     QTFSQQVMLFTRQGQQSAQLRLHPEELGQVHISLKLDDNQAQLQMVSPHSHVRAALEA
                     ALPMLRTQLAESGIQLGQSSISSESFAGQQQSSSQQQSARAQHTDAFGAEDDIALAAP
                     ASLQAAARGNGAVDIFA"
     gene            27351..27818
                     /gene="fliL"
                     /locus_tag="OPY25_001995"
     CDS             27351..27818
                     /gene="fliL"
                     /locus_tag="OPY25_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HCS0927614.1"
                     /translation="MTDSAINKKSKRSIWIPLLVLITLAACATAGYSYWRMQQQPTTN
                     AKAEPAPPPAPVFFVLDTFTVNLGDADRVLYIGVTLRLKDEATRARLNEYLPEVRSRL
                     LLLFSRQNAAELSTEAGKQKLIAAIKETLAAPLVAGQPKQVVTDVLYTAFILR"
     gene            27823..28827
                     /gene="fliM"
                     /locus_tag="OPY25_001996"
     CDS             27823..28827
                     /gene="fliM"
                     /locus_tag="OPY25_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HCS0927615.1"
                     /translation="MGDSILSQAEIDALLNGDSDTKDEPTPGIASDSDIRPYDPNTQR
                     RVVRERLQALEIINERFARQFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFITVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRHEDQNWRDNLVRQVQHSELELVANFADIPLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTVNGQYALRVEHLINPILNSLNEEQPK
                     "
     gene            28824..29237
                     /gene="fliN"
                     /locus_tag="OPY25_001997"
     CDS             28824..29237
                     /gene="fliN"
                     /locus_tag="OPY25_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HCS0927616.1"
                     /translation="MSDMNNPSDENTGALDDLWADALNEKKATTNKSAADAVFQQLGG
                     GDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            29237..29614
                     /gene="fliO"
                     /locus_tag="OPY25_001998"
     CDS             29237..29614
                     /gene="fliO"
                     /locus_tag="OPY25_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460931.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HCS0927617.1"
                     /translation="MMKTEATVSQPTAPAGSPLMQVSGALIGIIALILAAAWVIKRMG
                     FAPKGNSVRGLKVSASASLGPRERVVIVEVENARLVLGVTASQINLLHTLPPAENDTE
                     APVAPPADFQNMMKSLLKRSGRS"
     gene            29614..30351
                     /gene="fliP"
                     /locus_tag="OPY25_001999"
     CDS             29614..30351
                     /gene="fliP"
                     /locus_tag="OPY25_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460932.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HCS0927618.1"
                     /translation="MRRLLFLSLAGLWLFSPAAAAQLPGLISQPLAGGGQSWSLSVQT
                     LVFITSLTFLPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEQKISMQEALDKGAQPLRAFMLRQTREADLALFARLANSGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            30361..30630
                     /gene="fliQ"
                     /locus_tag="OPY25_002000"
     CDS             30361..30630
                     /gene="fliQ"
                     /locus_tag="OPY25_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HCS0927619.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALITGLIISILQAATQI
                     NEMTLSFIPKIVAVFIAIIVAGPWMLNLLLDYVRTLFSNLPYIIG"
     gene            30639..31433
                     /gene="fliR"
                     /locus_tag="OPY25_002001"
     CDS             30639..31433
                     /gene="fliR"
                     /locus_tag="OPY25_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HCS0927620.1"
                     /translation="MIQVISEQWLYWLHLYFWPLLRVLALISTAPILSERAIPKRVKL
                     GLGIMITLVIAPSLPANDTPLFSIAALWLAMQQILIGIALGFTMQFAFAAVRTAGEFI
                     GLQMGLSFATFVDPGSHLNMPVLARIMDMLAMLLFLTFNGHLWLISLLVDTFHTLPIG
                     SNPVNSNAFMALARAGGLIFLNGLMLALPVITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGIMLMAALMPLIAPFCEHLFSEIFNLLADIVSEMPINNNP"
BASE COUNT         7562 a         8426 c         8132 g         7348 t
ORIGIN      
        1 atcagcattt tttatagaga ttaatggatt ttatcggctg atttacccga cgtttagtat
       61 ttaccaggca taagttcttg cgggtcggta gcacataact gttgtactgg cagaaatgcc
      121 gctaccgatg ttttttactg tgtatcgcgc tggagagttc acgctcgcgg tcggcataca
      181 aactgaaagc acaaaaaaac cacccgtagg tggtttcacg acactgctta ttgctttgat
      241 tattcttgtc tttcccatgg tacccggagc gggacttgaa cccgcacagc gcgaacgccg
      301 agggatttta aatcccttgt gtctaccgat tccaccatcc gggctcggga aaaattggag
      361 gcgcgttccg gagtcgaacc ggactagacg gatttgcaat ccgctacata accgctttgt
      421 taacgcgcca aatttttttg gcttttcagc cagcatccgc tttacgccaa tgcttttaaa
      481 ctggagcggg aaacgagact cgaactcgcg accccgacct tggcaaggtc gtgctctacc
      541 aactgagcta ttcccgcagt atcaagcaac tttgttaatc gcttgatttt gttatcgtct
      601 ggcaatcagt gctgccgtcc gatgcgttgc attctactta cctgacgcac tgagtcaacg
      661 atatttttcg tcactcacga tcgtttgctg aaatttgcgg cgaaacgatc actgatcaag
      721 caaatctccg cgtgcagcgc tcaaatattg caacatggac cacaatgtta gcaccgctgc
      781 gacaaagaaa agcgcgatcc cggcatactc tacccagata ttcggacgcc acaagagcca
      841 cgccagcgcc accatctgcg cggtagtttt gactttaccg atccaggaga ccgctacact
      901 actgcgtttg cccagctccg ccatccattc acgcagagca gagataataa tttcgcgggc
      961 gatcatcgtc gccgcaggta acgtcaccca ccagctatga taatgctcgg tgaccagcac
     1021 catggcgatc gccaccagca ccttgtcggc gacggggtcg aggaaagcgc cgaaacgcgt
     1081 actctggttc cagcgtcgcg ccagaaagcc gtcaaaccag tcggtaatcg cggcaataca
     1141 gaaaatcagc gcgctgacca tcggcgccca ggcgaacggc aaataaaaca ccacgacaaa
     1201 gaatggaatc aggatgacgc gaaacagcgt gagcaacgta gggatattaa attgcatagt
     1261 gacgggtaac tatctgttgt cagtgaaatt acccctatgt tgctacagtg gcctcaatgt
     1321 ttcaacgacc agaagatctt ttctgccaga ccttgcgaaa tacccggcac ttttgcaatt
     1381 tcttctacgc tggcgttacg taatccttgc aaaccgccca tatatttcag cagcatctgg
     1441 cgacgtttag gcccaacgcc ttcaatagtt tccagcgtac tggtattttt aaccttcgcg
     1501 cgttttttac ggtgcccgcc gatcgcgtga tcgtgcgact catcgcgaat atgctgaata
     1561 acatgcagcg ccggcgagtc cggcggcagg ctaaacccct cgccttccgg ttcaaaaaag
     1621 agtgtttcca gaccggcttt tctgtccgcg cctttggcga cgccgagcag caaaggacga
     1681 tgcttatccc aggggacatc cagctcagcg aaaacggctt tcgcctgggc gagctgccct
     1741 tttccgccgt cgatcagaat aacatccgga atcttacttt cttctatggc cttgccataa
     1801 cgccgacgta gcacctgatt catcgccgcg tagtcatcac ccggcgtgat gcccgcgata
     1861 ttataacgac gatactcggc gcgtaacggc ccgttagcgt caaataccac acaggatgcg
     1921 accgtttgct cccccatggt atggctgatg tcaaaacatt ccatccgctt gatcgcagga
     1981 agttttaata ccgtcgccag cgcggtcaaa cgctgcgtga tggtggactg ctgcgaaagt
     2041 ttagtgacta aggccgttgc cgcgttggtc cgcgctagct tgagatagcg ggcgcgatcg
     2101 ccgcgcggtt ttgtctggac atgaatacgc cgtccggcaa gctccgacaa cgaatcggcc
     2161 agcagcgttt tatcgctcag attaaaatcg agtagtatct cgcccggtag cgtgcgcatc
     2221 tggctaccct gcaggtaaaa ctgcccgaca aaggtttcca ccacttcgcc cagttccgta
     2281 ccgccaggca cttttggaaa atagctgcgg ctgcccagta ccttaccctg gcgaataaac
     2341 aacacatgca cacaggccat acccgcatca aaagccacac cgataacgtc gagatcgtcg
     2401 cccgcattgg agacaaactg tttctccgtg acccggcgta ccgcctggat ctgatcgcga
     2461 atacgcgccg cctcttcaaa tgccaaatcc tggctggcct tttccatccg ggcaatcagc
     2521 tgtgttaaga cctggtcgtc cttgccggac aaaaacaacc ggacatactc cacctgttgc
     2581 gtgtactcct cctcgctgac cagtcctgca acgcaggggc ctaagcagcg gccaatctgg
     2641 tattgcaggc aaggacgcga gcggttgcga tacacgctgt tttcgcactg gcggataggg
     2701 aaaattttct gtaacagcgc cagcgtttcc ctaacggcat agccattagg aaatggaccg
     2761 aagtactcgc ctttcgcatg tttggcgcca cggtgcatcg ccagacgcgg atgggtatcg
     2821 ccgctcagaa aaataaaagg ataggattta tcatcacgca acaacacgtt gtaacgcggt
     2881 tgatacaact tgatgtaatt atgctcaagc agcagcgctt ccgtttcggt atgcgttacc
     2941 gtgacatcaa tgtgttgaat ttgcgcaact agcgcttcgg ttttacgcga agccaggttg
     3001 ctgcgaaagt agctggaaag acgctttttc aggtcttttg ctttaccaac atagataacc
     3061 gtaccgccgg cgtcatacat acgatagaca ccgggttggc tggtaacggt tttcaggaac
     3121 gcctttgcgt caaatatttc actcactggc ttgttaacgt ctccgcatta cacaggccat
     3181 ggcggattgc caggtgagtc agctcaacat caccatgaat gtttaattta ctgaacatac
     3241 gatagcgata gctgttcacc gttttaggac tgagattcag ctgttctgaa atctcattga
     3301 ccttctggcc cttggtgatc atcagcataa tctgcaactc gcgttcagac aaactggcga
     3361 acggcgtttc cgtttttgca ggctcaatct gactgagcgc catctgttga gcgatatcgg
     3421 aggcgatata acgttgtccg gaatacaccg aacgaatagc gctcaccacc tcctgaggcg
     3481 cagcgccttt gctgagatag ccagctgcgc cagcctgcat cactttggcg ggcaacgggt
     3541 tctccgtatg gacggtcagc atgatcactt tgatatccgc tgtcgatcgg gcaattttac
     3601 gcgtcgcctc aaggccgcca ataccgggca tgttcatatc catcagcacg acgtcaacgg
     3661 cgttagtacg gcaccatttt accgcatcct ctccgcagca cgcttcaccg acaactttaa
     3721 tgccctttat atcttcaaga atgcgtcgta tccctgcgcg caccagttcg tggtcatcaa
     3781 caagaagaac gttgatcaaa ggaatatctc cagaataggg ataacgctac tgatagttaa
     3841 tcgcccttat attagctggt tttatctcaa ctttgaaacg taaaaaaaca ccgggtattc
     3901 gattttgctc tcgtttttgg aaattatgtt gtacgtcatg tggcaactgc caacgttgta
     3961 gccccttctg acggcgctgt tccgggctgc tatttcataa tggtgacaaa aatttcacgt
     4021 tccgctgtct aaacactaat tagggaatca actttgtaac aataattaac gagtaaaata
     4081 cgcgtaataa acaaagaatg aagaaaatat atgcatcacg cggcaacgtt tattttgtgg
     4141 gtaacccctc tgctttttga tcaaaaaaca accactgcta tttttagcgt agcttatggt
     4201 atactccgcc gccttaacat ctgctatcgc acattttcac tgaaacataa cgaggaaaat
     4261 aaatgagtac gcctgatttt tccaccgctg agaataatca agaactggct actgaagtca
     4321 actgcctgaa agccatgtta acgctgatgc tgcaggcgat gggccaggcc gatgcagggc
     4381 gcgtgattct taaaatggaa aaacagatcg cgcagatgga tgatgaagca caagcggcgg
     4441 tattttccag tacggttaag caaattaaac aggcttaccg ccagtagtaa aaaaccggct
     4501 gttagcatcg ctttcagccg gtttcgcgtc tggcgcgaag catcgtcagc acgtcatatc
     4561 agacctgtcg ccgcagcgta gcaggcaatc tgtgttttat ttggcgcatt gaatttcttc
     4621 tgcatgtttt tctgatggaa gttaacggta ttttcagaaa tcgacagaat aatggcgatc
     4681 tccgatgagg tcttcccttc cgccgtccac ttcagaatct ctttctcacg tttactgaaa
     4741 cgcatctcag gcgccatcac catgtcgtct tcaagtcttg tcagcgccga aagactctcc
     4801 cgcgccagca gttgcaacct cagctccact tcatcgtagg taaacgagga gcagcgtaaa
     4861 ctgctacggg agaaagataa aaagcccagc gcccggttcg gcaacatcac acactgggtt
     4921 acgcctctgc gtaatccgaa acgctgggcg gcatcccaca tcgcctgcgc ttcatgaaat
     4981 agcacgtcat cccaatgtaa atgaccctgc ctgaaatttt ccggctttaa taccggatca
     5041 atcgcgaaat agttttcgga ctgataatgc gttacccacg cctgaggata agtggtacga
     5101 agcgatattt taggccgggt aaagggaacg ggatgacgaa cacacagggc ataataatca
     5161 aattccagcc gctgtgtctg atattgcaat tcagtataaa catcctctgc tgccgccatc
     5221 tcctgaaagc gtaacaacat tgcgcgtcgc caggtgaaga aatcattttc ctgcatattt
     5281 tatggtcacg cctttgatat tgataatcat tattatgaat gacttaaatt aacacataaa
     5341 tggtgtttat atataaggaa tatcggacga atcatagaat acttgagcgg cattacagtt
     5401 tttcgacttc cgccaaagag cgaggttaat aatctggcag aatgacttca taattattca
     5461 ttgcgctcgc ccgaggcacg gctaattcgg gcgagcgttg aaaaggtatt atttcactaa
     5521 aaatttctca aggaactggc gagtacgcgg atgctgagga tcggcgaaca aggttttcgc
     5581 cggcccctgt tcgacgattt gcccctgatc cataaatatt gcccggtcag ccacgtcacg
     5641 cgcaaagccc atttcgtgag tgacgatcac catcgtgcgc ttttcctgcg ccagctggcg
     5701 aatcgtatta agcacctcgc cgactaattc aggatcaagc gccgacgtcg gctcatcaaa
     5761 cagaatcact tccgggcgca tcgccagcgc gcgcgcaatc gccacgcgct gctgttgccc
     5821 gcccgacagg cggcgcggat aacgggtctc tttaccggcc aacccgactt tggctaacag
     5881 ttcccgcgcc agcgccgtcg cctcagcttt cggctctccc tttacaatca ccggaccttc
     5941 aatgatattt tccagcacgg tacgatgcgg gaacaggtta aaactctgaa agacaaagcc
     6001 gacatgctga cgtagctggc gaatcaaccc tttttgctgg ctgaatgggc gggcggtatc
     6061 gatgataata tcgcctactt taatggtgcc cgcttccggt tgttccagca ggttaataca
     6121 gcgtaataac gttgtcttcc ctgagccgct cgggccgata atggcgacga cttctccggg
     6181 cttcacctca aggtcgatac cgtgcagcac cgtttgacca tgaaattttt tgaccaggtt
     6241 ggtgacttcg atagcactca ttttggctct ctctcctggc ggttaagctg gttttcgaaa
     6301 tagttttgca gtgccgataa gacggtcgcc attacccagt agattaacga cgcggccaga
     6361 tacatggtaa acacctccag cgttcgcgag gtaattaact gcgcctggcg gaacaactcc
     6421 ggcacctgaa tcgtcgcggc gagcgatgta tctttcacca ggctgataaa gctgttgctc
     6481 aacggcggaa gcgcgacgcg ggccgcctgc ggcaaaatag cgcggcgtag cgtttgccac
     6541 ggcgtcatgc caatgctcgc cgccgcttcc cattgtccct tgtcgatagc cgagatcgcc
     6601 gcgcgcagcg tctcggacgt gtaagccgcg gtattgagcg ataaaccaat catcgccgcc
     6661 gggatagggt ccagctcaat accaaattgc ggcaggccgt aatagatcat aaataactgg
     6721 gcgataagcg gcgtaccgcg aaaaatcgag atataaaagc gcgccagcca gcgaaccggc
     6781 catagcggag acatccgcat cagcgccagc acaaatccca gcagcagacc aaaaaacata
     6841 ccgccaatac tcagttgcag ggtaaagacg gcgcctttaa gcaaatacgg cagcgattca
     6901 ataaccagtt ggatactttc ttgcattcgc gttgattacc tggaggttat acatgaggat
     6961 ggtaggcaaa cagcgcaggc gccccaccgg tatgaataaa gagaatcggc ccgtcatcgt
     7021 taaagcgttt ctggctgatg ccatctatca gacccgccat cgctttaccg gtatataccg
     7081 gatccagcag caccccctcc aggttcgcca gcagtttcac cgcctccatc cccgcgtcat
     7141 ttggcacgcc gtaacccggg gcaaaatagt catcccataa atgaatatcc gccgtcgccg
     7201 tcagcgccag ctggccggca atagcctgct gcaaggcaat cactttgggt ttctgctcgg
     7261 cgacagaacg tgaaacggtc acgccaatca gttcgacatc cggcatcaga tgttccagcc
     7321 cgacagctaa cccggcgtgc gttccggcgc tgccggaggc caccaccacc gaagagagcc
     7381 cgacgacctc ttcacactgc tggacgatct ccagggcgct ctctacgtat cccattgcgc
     7441 ccaacgcgct ggagccgccg accggaatca catagggcct gaacccttgc gcttcaatgc
     7501 gcgtcgccag cgtttgcagc tgcgcatccg gatcggttag cgcatcgcac atctcaattt
     7561 gtgtattaaa taaatccagt aacaggcgat taccattcgt caggtaattt tccgcggtgg
     7621 taccgattgg attttccagc aaggcgacgc aatgcagccc caatttggcc gcaaccgccg
     7681 ccgtctgacg gacatggttt gactgaatcg cccctgcggt tatcagcgta tccgcccctt
     7741 ctcgcagcgc gtcggccact agaaactcca gcttacgcag tttattgccg cccattgcaa
     7801 tgggcgtaac gtcatcgcgc ttaatgtaaa tctcacggcc aagataatca gacaatcgcg
     7861 gcaggtattc gagcggggtc ggcgcgccaa taagctccag gcgaggaaag cgcgttaagt
     7921 gatgtagtgg cattgagcct ccggtaacgt tgtggtgtgt tctttttatt atgcacgttg
     7981 atctaatgga aataaaaaag gcgccgattc acgcgcctcc gtttgctgac atagtatgag
     8041 gttgatattg cccggcggcg cactacctgc cgggcaacgt agagcattat tgggtcacgt
     8101 cagcgccaaa ccatttttcg gagagcgctt ttaaggtgcc atctttttgc atttccgcaa
     8161 tggcattatc taccgccttc agcaaatctt cgttgccttt acgtaacgca acgccggact
     8221 cctgacgcga aaacgcatca ccggtgacgg ccagcgtacc tttggttttt ttcaccagat
     8281 ccaacgccgc cagacgatcg actaaaatcg cgtcaatacg gcctacgcgc agatcctgat
     8341 attttgtagg atcatcgtca taggtgcgga tatccacgcc ctgaacatgt tgacgtagcc
     8401 actcttcata gttagtcccc agcccaacgc cgactttttt gccctgcaga tcggccgccg
     8461 ttttgatcgt gccttcattg ccttttttca ccagcgcctg aacgccggag acagtataag
     8521 gcgtagagaa atcatatttt ttcttgcgga cgtctgaaat cgtgacctgg tttatcacta
     8581 catcaatgcg tttagagtcc agcgacgcca gcattccgtc ccatttggtc ggcttcaacg
     8641 acgctttaac gcccagatgt tttgccaacg cctcggcgaa atcgacttca aaaccggtta
     8701 atttgccgtc gtcgccctga aagctaaacg gcggataggt accttccagc cctaccagca
     8761 gcgtgccgcg ttctttaact ttgttcagca aaccctcatc ggcaaagctc ttcgcgctca
     8821 ttcccgccac cagcgctaca gccattactc ccatcagtgc ctgacgtccc agcagtgcta
     8881 atttcatagt aaccccgaat attgccgtta atgaccatag actgtgtccc gccatggcgc
     8941 atcgtcatgt ctcgcgaacc tttgggggac tcagcctaat gtagaaggtt tgccacgttt
     9001 caccaacacg actctgctac atcttatgct tttttaatat atatcagaac tggcggtaaa
     9061 gggggatttc tgtctgggcg caatctgctg atgcgcttta tattgctggt atttacgcag
     9121 tgcgatacgg taattattgg tgctggtttc cggcaaccat ggcgccaggc tttcatcgag
     9181 aaaaccgtcc tgcagcagat cgtgggaaat gttttgctcg ctgaggtaat tgccaagacg
     9241 tcgtaaacgc acgacatatt cccgcaccgt gccatggctc atctcggttt gttcaaacaa
     9301 atactgcttg aaaccgataa tatcgaaaaa atcactctgc tttttgcagt gcaaatcgcc
     9361 gcaaaagcga cacaacgcca cccactcctt ctgctcccgc tgccaggcag cgtcgtcaag
     9421 tagcatatcc agctgtgaaa tagcgatttt attaacgatc ttgccacggc gaaccagcgt
     9481 aatgcggtcg agcaatttgt gacaatgcgc gcaatgcgtc tggctgtgtt taaagtcttt
     9541 aagatagcgg ctcaagggcc gccttttagg ttgctgcacc gtcatgagaa ctcctggtag
     9601 tctatatgtt gtgcggcact tttcgggtgc gatcatgcgc tacctataac ttacccagtt
     9661 tggtgcgtaa tcgtttgatg gcctgactat gcaactggct gacccgcgat tcgccgactt
     9721 ccagtaccgc gccaatctct ttgagattga gctcttcctg gtaatacagc gttaacacca
     9781 gttgctcgcg ttccggcagc gattcaatcg catccattac ccgctgtcgc aggtcgccct
     9841 ccagcagttg atgtaacggg ttttcctgtt gatgttcttc agtcaccagt tcgatgctat
     9901 cgccatgctc ttcccgccac tcatcgtaag agaaaagttg gctgttgttg gtatcgagca
     9961 acatctgacg atactccgca acagggatgc caagacgttc cgccacttcg gtttccgtcg
    10021 cattacgccc cagttcctgc tccagttgtc ccatcgcctg cgccacttcg cgggcattac
    10081 gccggacgct acgcggcacc caatcgcggc tgcgtaattc atccagcatc gccccacgaa
    10141 tacgctgcac tgcgtaagtg gtaaatgccg ttccttgcaa agcgtcatat cggtcgaccg
    10201 catttaataa cccgatgccg cccgcttgta gcagatcgtc cagttccacg ctcgccggca
    10261 atcgcacctg caggcgcaat gcttcgtgac gcaccagcgg tacataacgc tgccacagcg
    10321 agtgtttatc cattacacct tcagcggtat acagtgaatt cacgataaac agccctgcgt
    10381 taaatgagtt atcggcatga ttatccgttt ctacagaggg ttctatcgaa ggaataaggc
    10441 tataaaagaa gggttatttc acttatgtaa cctgtagcgc ctttttagcg gttcaaagag
    10501 cagaataaaa tcagccagat aggataaacg ggatgcgcaa aagcccaccc cgaacaaaac
    10561 tatgtcagaa gatgaatcat cgacagatcg tcgccagtac gcaccgtttc tatatggcga
    10621 tgaaaattcg ccgccacctc gctgttatgc tggctgcggg agtgaaagct atacacaata
    10681 ttggtaacgt catcccactc aagccgcccg cgctcatgca cgctggctgc cgttaatagc
    10741 ttaataaagg catattccgc cacgataata tacagcgcgc gtaacgggtc gacattcggc
    10801 tggttgggga aattattttc ccaaatttta tagagaatta aatttctgaa agcccagttc
    10861 ttctgctgct catccgcctg taaacagcgc gctaatgagg actcaatatc gctaaccttc
    10921 tgctccattg aaacgccctc ttccgccgtc agcacccgca gaagacactg gatatagtga
    10981 tcgaggataa cactgccacg actaagcggg agcgagcgga aatagttctg catctgcaat
    11041 accagcgagg tttttacctt gctgtccggc gcgatattca tcaattcctg cgccagcacg
    11101 ccggtctgca actgctcaag taacgcggca tacacctgtt ccagttcacc cagcgcggca
    11161 tcatcaattt tggcaaattt atgtgcatac atgacgaatt taatcaaccc atagagcgcc
    11221 gtttccgtac tgctgttggc atggttgatc agactcaggc aaaacagatt gagtaacttt
    11281 tgctgcggtg agaataacgg cgcagtattg aatgtctgct gaatgattgt tttttcgccg
    11341 agcgccattg cgtcaggatc gtttaaaatg cgggacgtta cctccggaca ggcaagactc
    11401 agggagttac gtacctcatt tttataggta tggtgcgccc gtgggaaaga ggaacaggta
    11461 tgacttaatg cctttgcgcc taacgttttt gtacccggca caaacggtcc tcatccagat
    11521 aagggcaact tcccagcgcc gaaggcagtt taatttcccc ccaatgatta ttgttctttt
    11581 tcagcagaat aatatggtct tgcgcgatgg tacgaatcgt cgtgtcttta ctggcgagat
    11641 actttttaac cgtcgtctta tccagcgtga ttttccagcc cttacaacaa tggtcgcgac
    11701 aggccgagcc agaacaggaa aagcgggtga caaaggcagg ttcagtgacg gtgatttctt
    11761 tcattacaca ggctccggaa ttaaaaaagg cagctttcgc tgccttgatt gtgtaccacg
    11821 tgtcggtgaa tcaatcgccg gattaacgca gtaaagagag gacgttttgc ggaacctggt
    11881 tcgcctgcgc cagaacggag gtaccggcct gctgcagaat ctgcgcgcga gacatgttgg
    11941 agacttcggt tgcgtagtcg gaatcttcga tacggctacg ggcagaagac aggttattta
    12001 cggtattgcc caggttggtg atagcggagt tgaaacggtt ctgaaccgca cccaggtcag
    12061 aacgaagtgt atcaacctgt gccaaggcag catcaatttt ctgcagtggg ttttcagtct
    12121 tatctgtatt aacctcttta agctcaccgc ctgttctgaa gttatgtttg tcaaggtcgc
    12181 ttgctaagta agtcttacca tcggtagcag taacaacttc agatttacca tttgcgccac
    12241 caaatttcac agctccagtt tgagcaacgc cagtaccatc tgtataagta gtggttttag
    12301 cagtaattgc acctgttttc tcatcatatg tagcggcata gaaatcgtcg cccattttca
    12361 ctgcatagcc accatcaata accttaccgt ttttatcctc aaacgatagt tttacaaggc
    12421 tagtattgtc cttatcggcg ccagtaaccc ctgctgcagc aagttgagcc gcaactgtgg
    12481 tcgtatcaac accctctttt gttacttcag caatttggtt gtgggttata gtggccgttc
    12541 cccgaatagc tgtagcttcc gcagttgcca acggagtttt atcagtcgta tcaatattaa
    12601 ctttctttgt agtttcatca taagtggctt tataaacacc agcagaagca ccgcctttaa
    12661 catctaaata gtattgacca tctttaaatt tgatatcagc cccagtaacc cccgttgcac
    12721 caccgccaat tgcagtttgg atatcagtat tgctctgggc tgtaatagga tctgtaccat
    12781 ttttataggt agttttatca acggttacag cagtttcttt cggggtgtag gcatcttgga
    12841 cattaagctt atcaagtccc agtgttttag agctgatttc ttttaaatca atatcgatag
    12901 tttcaccgtc gttggcacca acctggatgg tcagggtgtt gtcctgcgcc aggactttca
    12961 cgccgttgaa ctgagtctgg ccggatacac ggtcgatttc gttcaggcgc tgggtgattt
    13021 cagcctggat ggagtcgagg tcagactggg agttagtacc attcgcagac tgaaccgcca
    13081 gttcacgcac acgctgcagg ttgttgttga tttcgttcag cgcgccttca gtggtctgcg
    13141 caatggagat accgtcgtta gcgttacggg aagcctgagt cagacctttg atgttcgcgg
    13201 taaaacggtt agcaatcgcc tgtcctgccg catcgtcttt cgcgctgttg atacgcagac
    13261 cggaagacaa acgctcgata gcagtgccca gtgcggactg ggatttgttc aggttattct
    13321 gggtcaacag cgacaggctg tttgtattaa tgacttgtgc catgatcttt tccttatcaa
    13381 ttacaacttg atgttattgg gctgttgccc acggtttctc accgtaaccc ttgtatcggc
    13441 acctgaattt cgaactttag aaaatttttc acttcccccg atctttttct taggcggcga
    13501 aatagccgct ttatgcatca ttattccgcg cattattttt gcaaaattat cattaaactt
    13561 tgcctccaga ttgccgataa cgcgcttaac tactgtttgc aatcaaaaag gaagaaggca
    13621 tggcttcaat ttcatcatta ggtgtgggat caaacttacc gttagaccag ttgttgacag
    13681 acctgacaaa gaacgaaaaa ggacgcttaa cgccaattac caaacagcag agcgcgaatt
    13741 cggcaaagct aaccgcctat ggcacattga aaagcgcatt agaaaaattc cagacggcaa
    13801 ataccgcgtt aaataaagcg gatttattta agtctaccgt ggcgtccagc acgacagagg
    13861 acctcaaagt cagtactacc gcaggcgctg ccgcagggac ttataagatt agcgtaaccc
    13921 agcttgccgc cgcgcagtcg ctggcgacaa aaaccacctt cgcaaccacc aaagagcagt
    13981 tgggcgatac gtcggtcaca tcccggacaa ttaaaattga acagccggga cgtaaagagc
    14041 cgctggaaat taagctggat aaaggcgaca cctccatgga ggcgatccgt gacgccatta
    14101 atgacgccga cagcggtatc gccgccagta tcgttaaggt caaagagaac gaattccagt
    14161 tggtgcttac cgccaatagc ggtaccgaca atacgatgaa gatcacggtg gaaggcgata
    14221 caaaacttaa cgatctactc gcttatgaca gcaccaccaa taccggcaat atgcaagagc
    14281 tggtgaaagc agaaaacgcg aagctgaacg taaacggcat cgacattgag cgtcagagca
    14341 ataccgtaac cgacgcccct cagggaatta cactcaccct gaccaagaaa gtgaccgacg
    14401 cgaccgtgac ggtgacgaaa gatgatacca aggcgaaaga ggcgattaaa tcctgggtgg
    14461 atgcctataa ctcgctggtg gatactttta gctcattaac taaatatacc gccgttgagc
    14521 cgggcgaaga agccagcgat aaaaacggcg cgctgttagg cgatagtgtg gttcgtgcta
    14581 tccagaccgg gattcgggca caatttgcca atagcggcag taattctgcg ttcaaaacaa
    14641 tggcggaaat tggcatcacc caggatggga cttccggcaa actgaagatt gacgatgata
    14701 agctgaccaa ggtactgaaa gataacacgg ccgcagcgcg tgagctgctg gtaggcgatg
    14761 gtaaagaaac gggtatcacc accaaaattg ccaccgaagt gaaaagttat ctggcggatg
    14821 acggcattat tgataatgcg caggacaacg ttaacgccac gctgaaaagc ctgacaaaac
    14881 agtacctgtc cgttagcaac agcatcgatg aaaccgttgc ccgttacaag gcccagttta
    14941 cccaactgga taccatgatg agtaagctga ataacaccag tagttatttg acccagcaat
    15001 ttacagctat gaacaagtcc tgataacaga ggtcaccatg tacaccgcga gcggtatcaa
    15061 agcttatgcg caagtcagcg tggaaagcgc cgtgatgagc gccagcccgc atcagttgat
    15121 tgaaatgttg tttgatggcg cgaatagcgc tctggtgcgc gctcgcctgt ttttagaaca
    15181 aggcgatgtt gtcgcgaaag gtgaagcgtt aagcaaagcc atcaatatta tcgataacgg
    15241 gctgaaagcc ggcctcgatc aggaaaaagg cggtgagatt gcgacgaatc tttccgagct
    15301 atacgactat atgattcgcc gtttactgca ggctaatttg cgtaacgacg ctcaggccat
    15361 cgaagaagtg gaaaggttac tcagcaatat tgcagaagcc tggaagcaga tttcaccgaa
    15421 agcatctttc caggagtctc gttaatgacc tcaaccgtgg agtttatcaa ccgttggcag
    15481 cgtattgcgc tgctcagtca atcgctgctt gaacttgcgc agcgaggtga atgggatctc
    15541 ttactgcaac aagaggtctc ctatctgcaa agtattgaaa cggtgatgga aaagcaaact
    15601 ccaccgggca ttacgcgaag tattcaggat atggtcgccg gatacatcaa acaaacgctg
    15661 gataatgagc agctcctgaa agggctgctg caacagcgac tggatgaact gagtagtttg
    15721 atcggacaat ccacccgcca aaaatcactc aacaacgctt atggccgtct ttccggtatg
    15781 ttactcgtgc cagacgcacc tggcgcctca taatattttc ccgtctcgta tgaaaattct
    15841 tccatactcc agaggtcggc taaacgactt ctggagcacg gaagatgaaa aaccccacgt
    15901 tattgcagta cttccactgg tattatcccg acggaggaaa actctggtct gagctggcgg
    15961 aacgtgctga tgggctgaat gatatcggta tcaatatggt ctggctaccg cccgcctgta
    16021 aaggcgcctc cggcggctat tccgtaggct atgatagcta cgacctgttt gacctcggcg
    16081 aatttgacca aaaaggaact atcgcgacaa agtacggcga taaacgccag ttactgacgg
    16141 cgatagacgc gctcaaaaaa aataatattg cggtgctgct cgacgtcgtc gtgaaccaca
    16201 aaatgggcgc agacgaaaaa gaacgtattc gcgttcagcg cgtgaatcag gatgaccgca
    16261 cgcaaattga tgacaacatc attgaatgcg aaggctggac gcgctacacc ttccctgccc
    16321 gcgcgggcca gtattccaac tttatttggg actatcactg tttcagcggc attgatcaca
    16381 tcgagaatcc cgacgaagac ggcattttta agatcgtcaa tgactatacc ggcgatggct
    16441 ggaacgatca ggttgatgat gagctgggta atttcgacta tctgatgggg gaaaatatcg
    16501 attttcgcaa tcacgcggtt acggaagaga ttaaatattg ggctcgttgg gtcatggaac
    16561 aaacccattg tgacggcttt cgcctggacg cggtaaaaca tatacccgcc tggttttata
    16621 aagaatggat tgagcatgta caggcggttg cgccaaaacc gctgtttatt gtcgcagaat
    16681 actggtcgca tgaagtggat aaactgcaaa cgtacatcga tcaggccgac gggaaaacca
    16741 tgctgttcga cgcgccgttg cagatgaaat ttcatgaagc ctcgcgccag ggcgcggagt
    16801 atgacatgcg ccacattttc accggcacgc tggtagaagc cgaccctttt catgcggtga
    16861 cgctggtcgc taaccacgat acacaactgt tacaggcgct ggaagcgccg gtagaaccct
    16921 ggttcaaacc attggcctat gcgctgatcc tgcttcgtga aaacggcgta ccgtcggtgt
    16981 tttatcccga tttatacggc gccagctatg aggataacgg cgaaaatggc gagacctgtc
    17041 gggtcgacat gccggtgatt aaccaactgg atcggctgat cctcgctcgt cagcgttttg
    17101 cgcacggtat acaaacactc tttttcgatc atcccaactg tatcgccttt agtcgcagcg
    17161 gtactgaaga gaatccaggc tgtgtggtcg tactttccaa tggcgacgac ggtgaaaaaa
    17221 ccctcctgct cggcgacaat tacgctaaca agacctggcg tgattttctg ggaaaccgca
    17281 gtgagcatgt tgtaactaat gatcaaggcg aagcgacgtt cttctgcaac gcaggcagcg
    17341 tcagcgtgtg ggtcattgag gacgtgtgat gagcgttccc ggcggcagag cgctgccggg
    17401 aagcgaaatt acggcagcgg cgtcggcagc ggcgtttttt ctaacgcggc ggcgcactcc
    17461 ggcgtcggac gagcgacccg ttgcagcgtc atgccatcat attccagggt attcccgtcg
    17521 cgctcaatct catagagctc acgcttaacc gtaacattgg ttaagtcatc ggagagcatg
    17581 gtcagcttgc ccggcagagc aataacgcgc tgccactggc ggcagtccag cgtatcgcct
    17641 tctttagtca ccaccaggct ggcgatagct tcagggctca ccagcttacg ttgcgggcct
    17701 tttgactgcc agtacccttc cagaccggcc ggcgcgggcg ttttcaccac atcattatag
    17761 ttttccacct cggcgcatcc ggccagaacc agcaatgcgc caacgatcgc tacttttttc
    17821 atcattcatc ctgcatcaga agaaagaaga aagaagaaag aagaaagaag aaagaagaaa
    17881 gaagaaagaa gaaagaagaa agaagaaaga agaaagaaga attgtggcat taaagccctg
    17941 acgccgccag cctttccagg cgctggccgc aatttgatcc agtcggtatt accgcttatt
    18001 aggtgtaggc aaattctgtg atcggtgtag tatgcgcact tcttgtttca caccttctga
    18061 gttcagaggc taaacacatg tcatggcaac acttcaagca aacctggtta attaaattct
    18121 gggcgccggc ccctgcggtg atcgcagccg gtattctctc tacctactat tttggcatca
    18181 ccggcacgtt ttgggccgtg acgggcgaat ttacccgctg gggcgggcaa attttgcagc
    18241 tttttggcgt tcatgccgaa cagtggggct actacaagct gattcatctg gaaggtacgc
    18301 cgctgacgcg tatcgacggc atgatgatcc tcggcatgtt cggcggctgt ttcgccgcgg
    18361 cgctgtgggc caacaacgta aaactgcgta tgccgcgcag ccgaatccgt atcgtacagg
    18421 cggtggtcgg aggcatgatc gctggcttcg gcgcgcgtct ggcgatgggg tgtaacctgg
    18481 ccgccttttt taccgggatc ccgcagttct ccctacacgc gtggttcttt gcgctggcga
    18541 ccgctatcgg ttcctggttc ggcgcccgct ttacgttgct gccgatattt cgcataccgg
    18601 tgaaaatgca aaaggtctcc gcggcttcgc cactgacgca gaaaccggat caggcaagac
    18661 ggcgtttcag gctcggtatg ctggtcttta tcggcatgat tggctgggcg ttattaacgg
    18721 caatgcatca gccgaaactg gggctggcga tgctgttcgg cgtcgggttt gggctgctga
    18781 tcgagcgcgc gcaaatctgc tttacctcgg cctttcgcga tctgtggatc tccggacgcg
    18841 cccatatggc gaaagcgatt atttttggca tggcggtcag cgccattggt attttcagct
    18901 acgtgcagtt gggcgttgca cctaaaatta tgtgggctgg cccgaatgcg gtcattggcg
    18961 gactgctgtt cggttttggc atcgtgctgg cgggcggctg cgaaaccggc tggatgtacc
    19021 gcgccgtaga agtccaggtg cattactggt gggtgggcct cggcaatgtc atcggttcga
    19081 ccatcctagc ttactactgg gatgatttcg cgcccgcgct ggcgaccagt tgggataaag
    19141 ttaacctgct gaataccttt ggtccgctgg ggggtctgct ggtcacctat ctgttgttat
    19201 ttaccgcgct gatgttaatc atcggctggg aaaaacgttt tttccgccgt gcggggctga
    19261 cgcctgctaa ggaatctgta tgaaaaatat cgtccctgat taccgtctgg atatggttgg
    19321 cgaaccttgc ccgtacccgg cggtcgccac tctggaagcg atgccgcagc taaaaaaagg
    19381 tgagatcctg gaagtggtca gcgactgtcc gcagtccatt aataatattc cactggatgc
    19441 gcgcaatcac ggttatacgg tgctggatat tcagcaggat ggcccgacaa ttcgttatct
    19501 gattcaaaaa taagcgcata ctcccgctgt acgttacggc gggagacctt ttacggcata
    19561 accggcaaaa atctaaaacg cataaaagaa atcagacaag gtcgtcttgt gcgccgtggc
    19621 ataaatctat tatataacgt ataccgtttt aattttgtct gagccgatga aaaaaccatg
    19681 actattttaa gcaaaacata aaataattat tattttccct ctacgtcata aaagactatc
    19741 aggtatttat atttttactc actgacatta tcaggtgatg atttatttat gcacagcaga
    19801 agccaaaaaa atgataaaaa ttattttcat ctccattatt ggagtcgtct gtcttgccgc
    19861 tgcccgttac tcacccgtca cagtagtcaa tgcacatccg agcgccattg cccgctgtct
    19921 cgctgataat ctgtccccgt atgggtatat actggatctc catgaaacag atattccagg
    19981 tattagtaaa gaatttaccg tgtattatcg caacggcgca tatattgcag gaacattctg
    20041 gattgcaaac tcaatgacaa tagcctcaga actaatagta ggaatgaatg gcgtcagtaa
    20101 acaggcgtac cctattttta ataagtccct gcaacaatgt gcaacccgct tatcaataaa
    20161 atgagcgcgc ctcgcaaaaa caagcccaca taatcacgca ctggttgcat gggcgtcgcg
    20221 tcccccgcca ctgacttagg taagcgcccg ggagttcgct gcggatgtgt tgtcagccct
    20281 ggcttaaacc tgcatggaca tgacttcctg atacgcggcg accagcttat tgcgcacctg
    20341 aatccccatt tgcatagaga cggacgcttt ttgcatatca gccatcacgt cattaagcgc
    20401 aatgcccggc tcacccagag tgaatttttc cgcctgaacg cgcgccgccg tttgtctgtc
    20461 gctaatacga tccagcgcag catgtagctg gccggcaaaa ctcaccgtcg actgcgagtg
    20521 tgtttcttgc ccgtttgcgg ccatcgccgt cgcctgtaac tggctaatac ccccttcaat
    20581 cccctgtatt gctgccatgt tattcccctg gatgattttt tacgcagcag agattaccag
    20641 tttgtcaata agataaaggc gttaaataac gataaaaaac ctcggttttt agcgcataga
    20701 aaaattcgaa accacaaata atgagaccgt caatttttcg agtttgctga cccgggagtg
    20761 agtcttgttc cactttgcaa aaaacgccgt ccacgatcag tcacgaggtg cgagatgagt
    20821 gcgactgcat cgactgcaac ccaacctaaa cctctcgagt ggcttaatcg cctacgcgcg
    20881 aatccccgaa ttccgttaat tgtggcgggt tccgccgccg tggcgatcgt cgttgcgatg
    20941 gtgctgtggg ccaaaacgcc cgattaccgc acgctattta gcaacctttc cgatcaggac
    21001 ggcggcgcga tcgtcgcgca gttgacccag atgaatatcc cctatcgctt tgccaatggc
    21061 agcggcgcga ttgaagtgcc cgccgacaaa gtgcatgaac tgcgtctgcg tctggcgcag
    21121 caggggctgc ctaaaggcgg cgcggtaggc tttgaactgc ttgatcagga aaaattcggt
    21181 atcagtcagt tcagcgagca ggtgaattat cagcgcgcgc tggaaggtga actggcccgg
    21241 acgatcgaga cgctgggtcc ggtaaaaagc gcccgcgttc acctggcgat gccaaagccg
    21301 tcgctatttg tgcgggaaca aaaatcccct tccgcctccg tcaccgtcac actggaaccg
    21361 ggccgggcgc tggatgaagg acaaattagc gccgtggtac atctggtttc cagcgctgtc
    21421 gccggtttgc cgccaggaaa cgtcactctg gtcgatcaat ccggtcatct gctcacgcaa
    21481 tccaatacca gcggtcgcga ccttaatgac gcgcaattaa aatttgctaa tgatgtggaa
    21541 agccgcatcc aacgccgtat cgaagccatt ctgtcgccta tcgtcgggaa cggtaatgtt
    21601 cacgctcagg taaccgccca gttggatttt gccaataaag aacagacgga agagcactac
    21661 agcccgaacg gcgatgcgtc gaaggccact ctgcgttcac gtcagttgaa tattagcgaa
    21721 caggtaggcg cgggctatcc cggcggcgtg cctggcgcgc tgtcgaacca accagcgccg
    21781 cctaacgagg cgccgatcgc cacaccgccg accaatcaac aaaacgcgca gaatacgcca
    21841 caaaccagca ccagtaccaa cagtaacaac gctggcccgc gcaatacgca gcgtaatgaa
    21901 accagtaact acgaagtgga ccgcaccatt cgtcacacca aaatgaatgt gggcgatatt
    21961 gagcgtctct ctgtagctgt cgtggtgaat tacaaaacgc tggcggatgg caaaccgctg
    22021 ccattgaccg ccgatcagat gaaacagatc gaggatttaa cccgtgaagc gatgggtttt
    22081 tctgataaac gcggcgatac gctaaacgtg gtgaattcac cgtttagcgc agtggataac
    22141 accggcggcg aactgccctt ctggcaacag cagtccttta tcgatcagtt gctcgcggca
    22201 ggtcgctggt tactggtgct ggtggtggcc tggattctgt ggcgcaaagc ggtacatcca
    22261 cagttgacgc gccgcgttga agaagcgaaa gcggcgcagg aacaggcgca ggttcgccag
    22321 gaaaccgaag aagccgtgga agtacgcctt agcaaagacg agcagctcca gcaacgccgg
    22381 gctaaccagc gtctgggcgc tgaggtgatg agccagcgta ttcgcgaaat gtcagacaac
    22441 gatccgcgcg tggtggcgct ggtcattcgc cagtggatga gtaacgatca tgagtaatct
    22501 tagcggtacc gataaaagcg tcattttgtt gatgaccatt ggcgaagacc gggcggcaga
    22561 ggtgtttaaa cacctctcca cccgcgaagt acaggcgtta agtacggcga tggctaacgt
    22621 gcgtcagatc tccaacaaac aactgacgga cgtactatca gagtttgagc aagaagcgga
    22681 gcagttcgcc gcgctgaata tcaacgccaa cgaatacctg cgctccgtac tggttaaagc
    22741 gctgggcgaa gaacgcgcct ccagcctgct ggaagatatt ctggaaacgc gcgataccac
    22801 cagcggtatc gaaacgctca actttatgga accgcagagc gccgccgacc tgattcgcga
    22861 cgaacacccg cagattatcg ccaccattct ggtccacctc aaacgcagtc aggccgccga
    22921 tattctggca ctgtttgacg aacgactgcg tcatgatgtg atgctgcgta tcgcgacatt
    22981 tggcggcgta cagccggcgg cgctggcgga gttgaccgaa gtgctgaatg gcctgctcga
    23041 cggtcagaac ctgaaacgca gcaaaatggg cggcgtaaga accgcggcag aaattatcaa
    23101 cctgatgaaa acgcagcagg aagaagcggt tattaccgct gtgcgcgaat tcgacggcga
    23161 actggcgcag aaaatcatcg acgagatgtt cctgttcgaa aatctggtgg atgtggacga
    23221 tcgcagtatc caacgtctgc tgcaggaagt ggattccgag tcgctgctga tcgctctgaa
    23281 aggcgccgaa ccgccattac gcgagaagtt cctgcgcaat atgtcccagc gcgccgccga
    23341 tatcctgcgc gacgaccttg ccaaccgtgg cccggttcgt ctgtctcagg tggaaaacga
    23401 gcagaaagcg attctgctta ttgtgcgtcg tctggcggaa accggcgaaa tggtgattgg
    23461 cagcggcgag gatacctatg tctaatgaat tgccgtggca agtctggacc cccgacgatc
    23521 tcgctccgcc gccggagacg tttgtgccgg ttgaggctga taacgttacc ttgacagacg
    23581 atacgccgga gcccgaactc actgccgaac agcagctgga gcaggagctg gcgcagctaa
    23641 aaatacaggc ccatgaacaa ggttataacg ccgggctggc ggagggacgg caaaaaggac
    23701 acgcgcaggg ataccaggaa gggttagcgc aagggctgga gcaaggacaa gcccaggcgc
    23761 agacgcagca ggcgccgatt catgcccgta tgcagcagtt agtgagcgag tttcagaaca
    23821 cgcttgacgc gctcgatagc gttatcgcct cacggctgat gcaaatggcc ctggaggccg
    23881 cacgtcaggt catcggccaa acgccggcgg tggacaactc agcgctgatt aaacagatcc
    23941 aacaactgtt gcagcaagag ccgctcttta gcggcaagcc gcagttgcgc gtgcatccgg
    24001 acgacttaca gcgggtggaa gagatgctgg gcgccacgct cagtcttcac ggatggcggt
    24061 tgcgcggcga tccaacgttg catcacggcg ggtgtaaagt ctctgccgat gagggcgatc
    24121 tggacgccag cgtcgccact cgctggcaag agttgtgtcg cctggcggcg ccgggagtgc
    24181 tctgatgacc acgcgcctga cccgctggct taccgcgctc gacaactttg aagcaaaaat
    24241 ggcgttattg ccggcggtgc gccgttatgg acgtttaacc cgcgccactg gcctggtact
    24301 ggaggccacc ggtctccagc ttccgctggg cgccacctgc attattgagc gccaggacgg
    24361 ccctgaaacc aaagaggtgg aatcggaagt cgtcggtttt aacggccagc gtctgttttt
    24421 aatgccgctg gaagaggtcg aaggcattct gcccggtgcc cgcgtttacg cccgtaacgg
    24481 gcatggcgac ggtctgcaaa gcggcaaaca gttaccgctc ggcccggccc tgcttggtcg
    24541 ggtgctggat ggcggcggta aaccgctcga cggactgcct gcgccggata cgctggaaac
    24601 cggcgcgtta atcacgccgc cgtttaaccc gctacagcga acgccaatcg aacatgtgct
    24661 ggaaaccggc gtacgcgcca tcaacgcgtt gttaaccgta gggcgcggtc agcgtatggg
    24721 actctttgcc ggttccggcg tcggtaaatc ggttctgctt ggcatgatgg cgcgctacac
    24781 acgggcggac gtgattgtcg tgggtcttat cggcgaacgt ggccgcgaag ttaaagattt
    24841 tatcgaaaat attctcggcc ccgacggtcg cgcgcgttcg gtggtgatcg ccgccccggc
    24901 ggatgtttcg ccgctgctgc gaatgcaggg cgccgcctat gccacccgca tcgccgaaga
    24961 ctttcgcgat cgcggacagc atgtgttgct gattatggat tcgctgacgc gctatgcgat
    25021 ggcgcagcgt gaaattgccc tggcaatcgg cgaaccgcca gccaccaaag gttatccgcc
    25081 ctcggtgttc gcaaagctgc cagcgctggt cgagcgtgcc ggtaatggca tccacggcgg
    25141 cggctctatc accgcgtttt ataccgtatt gaccgagggg gacgaccaac aagatcccat
    25201 tgccgactcg gcacgcgcaa tcctcgacgg gcacattgtc ttgtcccgcc gcctggcgga
    25261 agccgggcac tacccggcca ttgatatcga ggcgtcaatc agccgggcga tgaccgcgct
    25321 cattaccgag cagcactatg cgcgggtacg gctatttaaa caattgcttt ccagtttcca
    25381 gcgtaaccgc gatctgatca gcgtcggcgc ctatgccaaa ggcagcgatc cgatgctcga
    25441 taaagccatt accttatggc cgcaattaga agcgttttta cagcaaggca tttttgaacg
    25501 ggccgactgg gaggactctc ttcaggcgct cgatttaatt ttcccgacgg tgtgataaat
    25561 caggagggcg acgatcatgg cacaacatgg cgctctggaa acactcaaag atctggccga
    25621 aaaagaggta gatgacgcgg cgcgtttact gggcgaaatg cgtcgcggct gccaacaggc
    25681 ggaagaacag ctcaaaatgc tgatcgatta tcagaatgag tatcgcagta atttgaacac
    25741 cgatatgggc aacggcatcg ccagtaatcg ctggatcaac tatcagcagt ttattcagac
    25801 actggaaaag gcgatagagc agcatcgcct ccagcttacg cagtggacgc aaaaagtcga
    25861 cctggcgctg aagagctggc gtgagaaaaa gcagcgactt caggcctggc aaaccttaca
    25921 ggaccgacaa accgcggcag cgctgttagc tgaaaaccgc atggatcaga aaaagatgga
    25981 tgaatttgct cagcgtgcag caatgaggaa acccgaatga tcaccctgcc ccaactgatc
    26041 accaccgata ccgacatgac cgcgggtctg acgtcaggaa aaaccaccgg ttcagccgag
    26101 gactttctgg cgctcctggc gggcgcgtta ggcgcagacg gcgcacaggg caaagacgcc
    26161 cgcatcacgc tggccgattt acaggcggca ggcggcaagt tatcgaaaga gctactggcc
    26221 caacatggcg agccgggcca ggcggtgaag cttgccgacc tgctggcgca aaaagcgaat
    26281 gcgacggatg aaacgcttac caatctgaca caagcgcagc atctactgtc tacgctaacg
    26341 ccatcgttga aaaccagcgc tctggccgca ttgagtaaaa cggcgcagca tgatgagaaa
    26401 acgcccgcgc tgagcgatga ggatcttgcc agtctgagcg ccttattcgc catgctgccc
    26461 ggacaacctg tcgcgacgcc tgtcgccgga gaaacgccgg ctgaaaatca catcgccttg
    26521 ccgtcactgt tacgcggcga catgctatcg gcgccgcagg aagagacaca tacgctctct
    26581 tttagcgagc atgaaaaagg gaaaaccgag gcgtcgcttg cgcgcgccag cgacgatcgc
    26641 gccatggggc catcactgac gccgctggtg gtcgctgccg ccgcgaccag cgcgaaagtg
    26701 gaggtggagg tggatagccc gtccgcgcca gtaacgcatg gcgcggcaat gccgacgctc
    26761 agcagcgcca cggcgcaacc gcaaccgcta cctgtcgcct cagccccggt actcagcgcg
    26821 ccgttaggca gccatgaatg gcaacaaacg ttcagtcagc aggtcatgtt atttacgcgt
    26881 cagggacagc aaagcgcgca gcttcgattg catccggaag agttaggtca ggtgcacatt
    26941 tcgctcaagc tggatgacaa tcaggcgcag ctccagatgg tatcgccgca cagccatgtc
    27001 cgcgccgcgc tggaagccgc cctgcccatg ttacgcaccc agttggcgga aagcggcatt
    27061 cagttgggac aaagtagtat cagtagcgaa agctttgccg gacagcagca gtcttcatcg
    27121 caacaacagt ctgcccgcgc ccaacacaca gacgcgtttg gcgctgaaga tgatatagcg
    27181 ttagcggcgc cggcctcgct tcaggccgcc gcgcgcggca atggcgcagt ggatatcttc
    27241 gcctaacgcc agaggtagca tgattatccg cgtcttttcc acgctttgtc gtggacagga
    27301 cacgggataa tcagccaata agcagtaccg aaacaggaag cccgtatcag atgactgact
    27361 ccgcgattaa caaaaagagc aaacgctcga tttggatacc tttgctggtg ttgattaccc
    27421 tcgccgcctg cgcgactgcc ggttatagct actggcgtat gcagcagcaa ccgaccacga
    27481 acgctaaagc ggaaccggct ccgccgcccg cgccggtatt ttttgtgctg gatacgttta
    27541 ccgtcaatct gggcgatgcg gatcgcgtgt tgtatatcgg cgtgaccctg cgtctgaaag
    27601 acgaagcgac gcgcgcacga ttaaatgaat atctgccgga agtgcgcagc cgtctgctgt
    27661 tgttattttc ccgtcagaat gccgccgagc tctcaacaga agctggcaaa caaaaactga
    27721 ttgccgccat taaagagacg ctggccgcgc cgctcgttgc cggacaacca aaacaggtcg
    27781 tcactgacgt gctttataca gcttttattc tgcggtaacg atatgggcga tagtattctt
    27841 tctcaggctg aaatcgatgc gctgttgaac ggcgacagcg acaccaaaga cgaacccact
    27901 cccggtatcg caagcgatag cgatattcgc ccttacgatc ccaataccca gcgtcgcgtc
    27961 gtgcgtgaac gcttgcaggc gctggagatt attaacgagc gtttcgcacg ccagttccgg
    28021 atgggattat ttaacctgct gcgccgcagc ccggatatta ccgtgggcgc catacgtatt
    28081 cagccgtatc acgaatttgc gcgtaacctg ccagtaccga ccaacctgaa cctgatccac
    28141 ctgaagccgc tacgcggcac cgggctggtg gtgttctcgc cgagtctggt gtttattacc
    28201 gtcgataacc tgttcggcgg cgacggtcgt tttccgacca aagtcgaggg ccgcgagttt
    28261 acccatacgg aacagcgggt catcaaccgt atgctgaaac tggcgctgga aggctatagc
    28321 gacgcatgga aagccattaa tccgctggaa gtggagtatg tgcgttccga aatgcaggtg
    28381 aaatttacca atatcaccac ctcgccgaac gatatcgtcg tcaatacgcc gtttcatgtg
    28441 gagatcggca atctgaccgg tgaatttaac atctgtctgc catttagcat gatcgagccg
    28501 ctgcgtgagc tgctggtgaa tccgccgctg gaaaactcgc gccatgaaga tcagaactgg
    28561 cgtgataacc tggtgcgcca ggttcagcac tctgaactgg agctggtggc caattttgcc
    28621 gatattccgt tacgtctttc ccagattttg aagctgaaac ccggcgatgt actgccgatt
    28681 gaaaaacccg accgcattat tgctcatgtg gacggcgttc cggtactcac cagccaatat
    28741 ggcaccgtaa acggacagta tgcgctacgc gtagaacatt tgatcaaccc aattttgaat
    28801 tcgctgaatg aggaacagcc caaatgagtg acatgaataa tccgtccgat gagaatactg
    28861 gcgcattgga tgatctgtgg gctgacgcgt taaacgagaa aaaagcgacc accaataaaa
    28921 gcgccgccga cgcggttttc caacagcttg gcggcggcga tgtcagcggt gctatgcagg
    28981 atatcgatct gattatggat atcccggtca aactgaccgt agagctgggc cgcacgcgaa
    29041 tgaccattaa agaactgctg cgtctgacgc aggggtcggt cgtcgcgctg gacgggctgg
    29101 cgggcgagcc gctggacatc ctgattaatg gctacctgat tgcccagggt gaagtggtcg
    29161 tcgtggcgga taaatacggc gtacgtatca ccgatattat tacgccatcc gagcgtatgc
    29221 gtcgtttgag tcgttaatga tgaagacaga ggccacggtt tctcagccca ccgcgccagc
    29281 cggatcgccg ctcatgcagg tgagcggcgc attaattggc attattgcgc tcattctggc
    29341 ggcggcctgg gtgattaagc gtatgggatt cgcgccaaaa ggaaatagcg tccggggact
    29401 gaaggtgtca gccagcgcct cgcttggccc gcgcgaacgc gtggtgattg tcgaggtcga
    29461 aaatgcgcgc ctggtactgg gcgtgaccgc ctcgcagatc aacctgctgc acaccctccc
    29521 gcccgcggag aatgacacgg aagcacccgt tgccccaccg gcggatttcc agaacatgat
    29581 gaagagctta ctcaagcgtt ccgggagatc ctgatgcgcc gtttgttatt cctttctctg
    29641 gcgggtctgt ggctttttag tcccgccgcc gctgcgcaac tgccggggct tatcagccaa
    29701 ccattagcgg gcggaggcca aagctggtca ttatccgtcc agacgctggt tttcatcacc
    29761 tcgctgacgt ttctgccggc gattttactg atgatgacga gcttcacgcg tatcatcatt
    29821 gtttttggct tgttgcgtaa cgcgctgggc acgccctcgg caccgccaaa tcaggtgtta
    29881 ctcggactgg cgttgttttt gacctttttt attatgtcgc ccgtcattga caagatttac
    29941 gtggatgctt accagccgtt tagcgagcag aaaatttcta tgcaggaagc gctggataaa
    30001 ggcgcgcaac cgttacgcgc gttcatgctg cgccaaaccc gcgaagccga tctggcgctg
    30061 tttgcccgtc tggccaatag cggtccgtta cagggaccgg aagcagtacc gatgcgtatc
    30121 ctcctgcccg cttatgtcac cagcgaatta aagacggcgt ttcagatcgg ttttacgatt
    30181 ttcatccctt ttttgattat cgacctggtg atcgccagcg tactgatggc gttagggatg
    30241 atgatggtgc cgccagcgac aatcgccctg ccgtttaagc tgatgctgtt tgtgctggtc
    30301 gatggttggc aattgcttgt ggggtcgctg gcccaaagct tttacagtta gaggcgcaaa
    30361 atgactcctg aatccgtcat gatgatgggg accgaggcga tgaaagttgc tctcgccctg
    30421 gctgcgccgc tgttactcgt cgcgctgatt accggcctca ttatcagcat cttgcaggcc
    30481 gcgactcaga ttaatgaaat gacgctgtcg tttatcccta aaatcgtcgc ggtattcatc
    30541 gcaattatcg ttgccggccc gtggatgctc aacctgctgc tggactacgt acgcactctg
    30601 ttcagcaatt taccttatat catcggataa acagaacgat gatacaggtt ataagcgagc
    30661 aatggctata ctggctgcat ctctatttct ggcctttgct gcgcgtactg gcgctgattt
    30721 caacggcgcc cattctcagc gagcgcgcta ttcccaagcg ggtaaaactg gggttgggaa
    30781 taatgattac cctcgttatc gcgccgtcgc taccagcaaa cgatacgccg cttttttcta
    30841 ttgccgcctt atggctggcg atgcaacaaa ttctgatcgg tattgcgctg ggatttacca
    30901 tgcaattcgc ctttgcggcg gtgcgtaccg caggtgagtt tatcggtctg caaatggggc
    30961 tttcctttgc caccttcgtc gacccgggca gccacttgaa tatgccggtt ctggcgcgta
    31021 ttatggatat gctcgccatg ctactgtttc tcacctttaa tggccatttg tggcttattt
    31081 cgctgctggt cgataccttc catactctgc ccatcggtag taacccggtg aacagtaatg
    31141 catttatggc gctcgccagg gccggagggc tcattttctt aaacggactg atgctggcat
    31201 tgccggtcat taccctcctg cttacgctca acctggcgct ggggctatta aaccgcatgg
    31261 cgccgcagct ctcgatattt gttatcggtt tcccgcttac cctcaccgtc ggcattatgc
    31321 tgatggccgc gctaatgcca ttaattgcgc cgttttgcga acatttattc agcgaaattt
    31381 tcaatttgct tgctgatatt gttagcgaga tgccgataaa taataaccca taatttttat
    31441 cctgttttac taaggtttat ccgaaaat
//
LOCUS       DAJVKX010000043        31254 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000043 DAJVKX010000000
VERSION     DAJVKX010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 31254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31254
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.043"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(31..237)
                     /locus_tag="OPY25_002002"
     CDS             complement(31..237)
                     /locus_tag="OPY25_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HCS0927621.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     RDKQHLSVMSEVNRQVMRLQTEMA"
     gene            564..1121
                     /locus_tag="OPY25_002003"
     CDS             564..1121
                     /locus_tag="OPY25_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HCS0927622.1"
                     /translation="MTLRKILAMSCLLLPIMACAHNLEDNQRVPPVGIADRGELTLNK
                     DEFSYKNWNSAQLAGKVRVLLHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSIESNKKLYPWSQFIVDSNGVARNAWQLKEEGSAVIVLDKDGRVQ
                     WVKDGALTQQEVQQVVDLLHKLLSK"
     gene            complement(1111..1851)
                     /gene="cysQ"
                     /locus_tag="OPY25_002004"
     CDS             complement(1111..1851)
                     /gene="cysQ"
                     /locus_tag="OPY25_002004"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HCS0927623.1"
                     /translation="MLEQVCQLARNAGDAIMQVYDGAKPMEYARKQDDSPVTAADIAA
                     HTVILEGLRTLTPDIPVLSEEDPPAWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIEQGKPVLGVVYAPVLKVMYYAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHTD
                     DELTEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTSVWDTAAGHAIAVAAGA
                     HVHDWQGKTLDYTPRESFLNPGFRVTIY"
     gene            2118..4061
                     /locus_tag="OPY25_002005"
     CDS             2118..4061
                     /locus_tag="OPY25_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2',3'-cyclic-nucleotide
                     2'-phosphodiesterase/3'-nucleotidase"
                     /protein_id="HCS0927624.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLIHAARNEVKNSVLVDNGDLIQGSPLGDYMAAKGHKDGDVHPVYK
                     ALNTLDYAVGNLGNHEFNYGLDYLHNALAGAKFPYVNANIIDVKTQKPLFTPYLIKET
                     SVIDKDGHPHTLKIGYIGFVPPQIMIWDKANLSGKVTVNDITETARKYVPEMREKGAD
                     IVVVIAHSGLSADPYHSMAENSVYYLSEVPGVDAIMFGHAHAVFPGKDFADIKGADIA
                     KCTLNGIPAVMPGMWGDHLGVVDLVLNNNSGKWQVTQAKAEARPIYDAAAKKSLAAED
                     SKLVGILKADHDATREFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHFIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASFVEVEKGQLTFRNAADLYLYPNTLVVVKAS
                     GKEVKEWLECSAGQFNQIDIHSNKPQSLINWDGFRTYNFDVIDGVNYQIDVSQPARYD
                     GECQMVNPQAERIKNLTFNGKPVDPNATFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRAVLAAWIGAESKRAGEIHPAADNNWRLAPIHSDTALDIRFETSPGDKAAAFIKEKG
                     QYPMKKVGVDDIGFAIYQVDLSK"
     gene            complement(4119..4505)
                     /locus_tag="OPY25_002006"
     CDS             complement(4119..4505)
                     /locus_tag="OPY25_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCS0927625.1"
                     /translation="MRAHTLSRQLREGNLFAEQCPSREVLKHVTSRWGVLILVALRDG
                     THRFSDLRRKMGGVSEKMLAQSLQALEQDGFLNRVSYPVVPPHVEYSLTPLGEQVSDK
                     VAALADWIELNLPQVLAQRERLSDGG"
     gene            4593..5441
                     /locus_tag="OPY25_002007"
     CDS             4593..5441
                     /locus_tag="OPY25_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCS0927626.1"
                     /translation="MIAITGATGQLGQHVIENLLKTTPASHLVAIVRNPKKAAPLSQR
                     GIAVRQADYANEAALTTALQGVDKLLLISSSEVGQRTAQHRNVIQAVIAAKVKFIAYT
                     SLLHADKSPLALADEHIETEKMLAESGIPHTLLRNGWYTENYLASVPAALKHGVFIGA
                     AGEGKIASAMRADYAAAAARVIREEGHAGNVYELAGDNAWTLSQLADELTHQSGKKIV
                     YQNLSEVDFAAALKGAGLPDGLADMLANSDAGAAKGGLFDDSHTLRKLIGRPTTALTE
                     SLRSVL"
     gene            5522..6487
                     /locus_tag="OPY25_002008"
     CDS             5522..6487
                     /locus_tag="OPY25_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0927627.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPDYPALLQSMGRYLALGLI
                     ALPIAWLGRTRLRQLTRKDWSTALSLTLMGNVIYYACLASAIQRTGAPVSTMIIGTLP
                     VVIPLFANVLYSQRDGRLSWLRLAPALALIGFGLLCVNIAELSQGLSDVSGWRYGSGI
                     VLALISVACWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYAATCLWLSIQ
                     NPMFTLPFGPHPALFIGLMIAIAVLCSWVGALCWNIASQKLPTVILGPLIVFETLAGL
                     LYTFILRQEIPPFLTLSGIALLVAGVVIAVRAKPEKATVVPVTER"
     gene            6590..7252
                     /gene="ytfE"
                     /locus_tag="OPY25_002009"
     CDS             6590..7252
                     /gene="ytfE"
                     /locus_tag="OPY25_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HCS0927628.1"
                     /translation="MAYRDQPLGELALSIPRASALFRQYDMDYCCGGKQTLARAAARH
                     DVDIDIIEAQLAQLAEQPIEKDWRAVPLADIIDHIVVRYHDRHREQLPELILQATKVE
                     RVHADKPNVPRGLTKYLTALHEELSSHMMKEEQILFPMIKQGMGRQATGPISVMESEH
                     DEAGELVDVIKHVTQNVTPPPEACTTWKAMYNGINEMIDALMEHISLENNVLFPRALA
                     GE"
     gene            complement(7319..8707)
                     /locus_tag="OPY25_002010"
     CDS             complement(7319..8707)
                     /locus_tag="OPY25_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927629.1"
                     /translation="MLRIKQFCLSILLMLAPVLALACSDIPYALFHYQPWGQGTKYVV
                     EEDYGYSINFKDIEIREVKFSQLRHVPDRIVNEYNDRGKMSNDFVHVAAFSSLIKNDF
                     WQFYWLTDGQHILWAGKIVQNPPGKPPVDAATFRAYGRFAADKDSLYFDGERTDDNHG
                     EKRVDMDSLQQVGGNIKLRDSGDVLKDRRNLYFQGRWLASAQGYSILGVKSWEQRNIL
                     FSPTSCDTTSNPGPWDTILRTATQVFVNGVAIDADPNSFHVVRWVAGVQLLYRDKAGV
                     KRYYFGKDCLNTFNVQRDKVTWMTREASRRGDDCRIATIPNVDPEYFHPIHYNWTVAQ
                     YKDLLYQVKYVSPVDRVLTITRLPDPQVQLKAGANLVGKQIYFIGDGGVQIIDLIGPL
                     VWFKSPDGSFSDVFAHDDRYLYFFGDTLVDSGQRRNVTRTLDTAHIDKSGYYLVTEEG
                     KYEVINNAFTSR"
     gene            complement(8722..9861)
                     /locus_tag="OPY25_002011"
     CDS             complement(8722..9861)
                     /locus_tag="OPY25_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DKNYY domain-containing protein"
                     /protein_id="HCS0927630.1"
                     /translation="MTIRRWILSATLLLLPVPAFADFQYQQDKDGVFYTADDEPQILS
                     RLPDVSYSHLRRIADLSHPQDPRPLIEINPDSHNCDDNHICQHAYLSDGHFILWAGKI
                     VQNTGDEPAVDVASFQSFGAFAADKHGLYFDGKRRDSNAGEKRVDMATLAETKIWNLL
                     RDKNNLYYEGRWLGRADGFRVLRLDSTSAREFIVTTAQRVIVNGIPITADANTFQIIR
                     WMPGEVLIYRDKTGKHDYEIDNSSRYCGYFNIGLREVTWLKHEATNAGSSCKVETLPG
                     VDPEYFFRLNGNTGWYKDRIYQVSTNALGEGVLRIFTSQEKLPALKIDRVTYNYYHLA
                     LSADGQLYRQISRDQWQSYNPILTEWTTVSPAPTDVISLLPSDYH"
     gene            complement(10199..11602)
                     /gene="cycA"
                     /locus_tag="OPY25_002012"
                     /gene_synonym="dagA"
     CDS             complement(10199..11602)
                     /gene="cycA"
                     /locus_tag="OPY25_002012"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001541380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HCS0927631.1"
                     /translation="MVDQVKVAADEQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPGLSDWVASLAVVVLLLSLNLATVKMFGEM
                     EFWFAMVKIVAIVALIVVGLVMIAMHFKSPTGVEASFAHLWNDGGWFPKGISGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLMVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKKRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWF
                     IALGLGWLFLRKNKLAK"
     gene            complement(11898..12518)
                     /gene="fklB"
                     /locus_tag="OPY25_002013"
     CDS             complement(11898..12518)
                     /gene="fklB"
                     /locus_tag="OPY25_002013"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCS0927632.1"
                     /translation="MATPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRERFKAMAAEGVKYLEENREKDGVNSTES
                     GLQFRVLTQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIAGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            12738..13373
                     /locus_tag="OPY25_002014"
     CDS             12738..13373
                     /locus_tag="OPY25_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OapA family protein"
                     /protein_id="HCS0927633.1"
                     /translation="MPGRFELKPTLAKIWHAPDNFRIMEPLPPMHRRGIIIAAIVLVI
                     GFLLPASETSDSPVVTREAQLDLQSQSQPPTEAQLQAQLVAPQNDPDQVAPVASEPIQ
                     EGQPEEQNQPQTQPFQQDSGIGQQWRSYRVEPGKTLAQLFRDHGLPPTDVYAMAQVEG
                     AGKPLSNLKNGQMIKIRQNASGVVTGLTIDGDNGQQVLFTRQPDGSFIRAQ"
     gene            complement(13423..14349)
                     /locus_tag="OPY25_002015"
     CDS             complement(13423..14349)
                     /locus_tag="OPY25_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0927634.1"
                     /translation="MDTQRQASPFARKNVVYVCAAFCCLLWGSAYPAIKSGYDLFQIA
                     TDDIPSKIVFAGYRFLFAGGLLLLFALLQRKPIGRFRPRQFAQLTLLGLTQTSLQYLF
                     FYIGLAFTSGVKGSIMNATGTFFSVLLAHFIYQNDRLSYNKTLGCILGFAGVMVVNVS
                     NGLDFSFNLPGEGSVVLAAFILSAATLYGKRLSQTVDPMVMTGYQLGIGGLVLVIGGY
                     VFGGTLTIHGFSSVAILVYLTLLSSVAFALWNILLKYNRVGMIAPFNFLIPVSGAALS
                     AIFLGENILEWKYMIALVLVCSGIWWVNKVKR"
     gene            complement(14497..14946)
                     /gene="rplI"
                     /locus_tag="OPY25_002016"
     CDS             complement(14497..14946)
                     /gene="rplI"
                     /locus_tag="OPY25_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCS0927635.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNV
                     EYFEARRAELEAKLADVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVDVAKSEVRLPNGVLRTTGEHEVNFQVHSEVFAKVIINVVAE"
     gene            complement(14988..15215)
                     /gene="rpsR"
                     /locus_tag="OPY25_002017"
     CDS             complement(14988..15215)
                     /gene="rpsR"
                     /locus_tag="OPY25_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCS0927636.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            complement(15220..15534)
                     /gene="priB"
                     /locus_tag="OPY25_002018"
     CDS             complement(15220..15534)
                     /gene="priB"
                     /locus_tag="OPY25_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HCS0927637.1"
                     /translation="MTNRLTLSGTVCRAPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            complement(15541..15936)
                     /gene="rpsF"
                     /locus_tag="OPY25_002019"
     CDS             complement(15541..15936)
                     /gene="rpsF"
                     /locus_tag="OPY25_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCS0927638.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYSAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            complement(16007..16213)
                     /locus_tag="OPY25_002020"
     CDS             complement(16007..16213)
                     /locus_tag="OPY25_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927639.1"
                     /translation="MWQKSTLTTVSIFLPQQAVYSGMRYEVNISAAKCDGTGVTFGTI
                     NNCTITLSLPAGASIITRHFSADL"
     gene            16407..16682
                     /locus_tag="OPY25_002021"
     CDS             16407..16682
                     /locus_tag="OPY25_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0927640.1"
                     /translation="MRARIMLFLAALLPGITATAAIELNNHQATNMDDVRSLGVIYIN
                     HNFATESEANLALNDEADARNAMYYHAILIREPGSNGNIHASANIYR"
     gene            complement(16812..17498)
                     /locus_tag="OPY25_002022"
     CDS             complement(16812..17498)
                     /locus_tag="OPY25_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCS0927641.1"
                     /translation="MQKLKQQVFDANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKVDDMVVVDMDGKVVEGRYRPSSDTATHLALYQRYPSLGGVVHTHSTHATAW
                     AQAGMAIPALGTTHADYFFGDIPCTRALSEEEVQGEYELNTGKVIIETLGEVEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVARMAWIARGINPGLNPIDDYLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(17498..18352)
                     /gene="ulaE"
                     /locus_tag="OPY25_002023"
     CDS             complement(17498..18352)
                     /gene="ulaE"
                     /locus_tag="OPY25_002023"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HCS0927642.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLRLAKTLGFDFVEMSVDETD
                     ARLARLDWSREQRLALVSAVAETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQQANDETRCRFRDGLKESVDMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPCFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAENPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            complement(18362..19012)
                     /gene="ulaD"
                     /locus_tag="OPY25_002024"
     CDS             complement(18362..19012)
                     /gene="ulaD"
                     /locus_tag="OPY25_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCS0927643.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSCDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG"
     gene            complement(19026..19490)
                     /gene="ulaC"
                     /locus_tag="OPY25_002025"
     CDS             complement(19026..19490)
                     /gene="ulaC"
                     /locus_tag="OPY25_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HCS0927644.1"
                     /translation="MKLRDSLAENNSIRLQAEANTWQEAVKIGVDLLVAADVVEPRYY
                     QAILDGVEQFGPYFVIAPGLVMPHGRPEEGVKKTGFSLVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEANFDRLRACRTAQEVLDLIDRTNAAA"
     gene            complement(19500..19805)
                     /gene="ulaB"
                     /locus_tag="OPY25_002026"
     CDS             complement(19500..19805)
                     /gene="ulaB"
                     /locus_tag="OPY25_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HCS0927645.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKAHFPQDVK"
     gene            complement(19821..21218)
                     /gene="ulaA"
                     /locus_tag="OPY25_002027"
     CDS             complement(19821..21218)
                     /gene="ulaA"
                     /locus_tag="OPY25_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCS0927646.1"
                     /translation="MEILYNIFTIFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIERMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVSFYIFGYSMWTTII
                     CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRAL
                     RAEEDAEKQLAEQSA"
     gene            21581..22645
                     /gene="ulaG"
                     /locus_tag="OPY25_002028"
     CDS             21581..22645
                     /gene="ulaG"
                     /locus_tag="OPY25_002028"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCS0927647.1"
                     /translation="MSKVQSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKTGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPQTCVDLWVGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDVRAVNYLFKTPG
                     GNLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAESLNTKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            22750..23505
                     /gene="ulaR"
                     /locus_tag="OPY25_002029"
     CDS             22750..23505
                     /gene="ulaR"
                     /locus_tag="OPY25_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HCS0927648.1"
                     /translation="MTEAQRHQILLDMLAQLGFVTVENVIERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTADGLYKTDMLTAMAEQKMLSVVGKLVALVDSSKIGERAGMLF
                     SRADQIAMLITGKNANPQVLQQLEAQGVSILRV"
     gene            complement(23502..24251)
                     /gene="yjfP"
                     /locus_tag="OPY25_002030"
     CDS             complement(23502..24251)
                     /gene="yjfP"
                     /locus_tag="OPY25_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCS0927649.1"
                     /translation="MIAIETRQLAGGVVLHAFPEGKRAVPLPCVVFYHGFTSSSLVYS
                     YFAVALAQAGFRVVMPDAPEHGARFGGDSQGRIHRFWQILHQNMQEFTTLRAAIQAEN
                     WLLDGRLAVGGASMGGMTALGIMTRHREVKCGASLMGSGYFTGLARTLFPPLSPQNPA
                     QQAEFDNIIAPLREWEVTHQLERLADRPLLLWHGQEDDVVPAIETFRLQQALAGAKLD
                     KHVTCLWAAGVRHRITPEALSATVAFFRQHL"
     gene            24435..24764
                     /gene="bsmA"
                     /locus_tag="OPY25_002031"
     CDS             24435..24764
                     /gene="bsmA"
                     /locus_tag="OPY25_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HCS0927650.1"
                     /translation="MIIRKRDRVMRRFAPLIAALLLSACSMLQGTPQPAPPVADHPQE
                     IRRDQTQGLQRMGTVSALVRGSPDDAIDEIRAKAAAAKADYYVILMVDETVVTGQWYS
                     QAILYRQ"
     gene            24895..25170
                     /locus_tag="OPY25_002032"
     CDS             24895..25170
                     /locus_tag="OPY25_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0927651.1"
                     /translation="MKQELALSSLLLSAGLVSTTAQSAEFASADCVTGLNEIGLISVS
                     NVAGNPQDVERIIALKADEQGASWYRIIQMYEEQQSNNWRVQAILYA"
     gene            complement(25215..26837)
                     /locus_tag="OPY25_002033"
     CDS             complement(25215..26837)
                     /locus_tag="OPY25_002033"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463238.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HCS0927652.1"
                     /translation="MSWQTHTVFNQPAPLNNSNLFLSDGALCEAVSREGAGWDSDLLA
                     SIGQQLGTAESLELGRLANAHPPELLRYDPQGQRLDDVRFHPAWHLLMQGLCANRVHY
                     LAWEEEARAGSFVARAARFVLHAQVEAGTLCPVTMTFAATPLLLQMLPATFHDWLAPL
                     RSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVLSNTTHAERLADDSYRLVGHKWFFS
                     VPQSDAHLVLAQAKGGLSCFFVPRFLPDGQRNSVRLERLKDKLGNRSNASAEVEFQDT
                     VGWRLGEEGEGIRHILKMGGMTRLDCALGSHGLMRRAFSVAIYHAHQRQAFGKPLIEQ
                     PLMRQTLSRMALCLEGQTALLFRLARAWEQRREAKEALWARLFTPAAKFAICKQGIPF
                     VAEAMEVLGGMGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLTKQHGVYDVLS
                     EAFAEVKGQDRHYDRAVRQLQQRLRKPDEAMGREITQQLFLLGCGAEMLRHASPPLAQ
                     AWCQMMLDTRGEMPLPAQVQNDLLLRATGGLR"
     gene            complement(26922..28085)
                     /locus_tag="OPY25_002034"
     CDS             complement(26922..28085)
                     /locus_tag="OPY25_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HCS0927653.1"
                     /translation="MLRHNVPVRRDLDKIACDHGFDFHVIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVERAVRDEQIMQQLAIPPLYWDVIAESWRSRDPSLYGRM
                     DFVWCGKDPVKLLEYNADTPTSLYESSYFQWLWLEDARRSGAIPRDADQYNAIQERLI
                     ARFSELYSREPLYFCCCEDTDEDRTTVLYLQDCAQQAGQETRFIYIEELGLGVGGVLT
                     DLDDNVIRRAFKLYPLEWMMRDDNGPLLRKRREQWIEPLWKSILSNKGLLPLLWRFFP
                     GHPNLLPAWFEGEKSLAAPGESSVRKPIYSREGGNVTIFDERQNVIDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIIDDEASGMGIREDNTLITKDTSRFVPHYIAG"
     gene            complement(28088..28726)
                     /locus_tag="OPY25_002035"
     CDS             complement(28088..28726)
                     /locus_tag="OPY25_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HCS0927654.1"
                     /translation="MAKKRKSRSTSGVGHSAIRRIAEPVNPFERQRNRYTPKYLTLAI
                     MGGAAFFLLKGYGDGSNSDNDGDGTFYATVNDCIDDGNSASVCADGWNNAKTEFYANV
                     PKQLTQESCQSQFGDCYFDITERSWVPVLSGFLLSRAIRQNRDEQYIYSSGGSSYVSR
                     PVWRTTSGDYAWRSGTGKSDTVTSPGYIIRKASTVSRGGYGRSSSARGHWGG"
     gene            complement(28736..29134)
                     /locus_tag="OPY25_002036"
     CDS             complement(28736..29134)
                     /locus_tag="OPY25_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HCS0927655.1"
                     /translation="MHILDALLAFCAYFFIGAAMIIVFLFIYSKITPHNEWQLIKNNN
                     TAASLAFSGTLLGYVIPLSSAAINSVSIPDYFAWGGIALVIQLLIYGCVRLYMPTLSE
                     KIIHHNVAAGLFMGTAALAGGIFNAACMTW"
     gene            complement(29152..29835)
                     /locus_tag="OPY25_002037"
     CDS             complement(29152..29835)
                     /locus_tag="OPY25_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463234.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HCS0927656.1"
                     /translation="MARDRGSPMMQFFQRLLGKTSTPAPIRGPLGLHLNAGFTLDTLA
                     FRLLESSLLVALPGEKYTVAAASRIDLGGGSQIFRYYTSGDEFLQINTTGGTDVDDID
                     DIKLFVYEESFGINEERHWRSAIAPAAIGPMTLNWQERRWQRFFNHEEPGNIEPVYML
                     EKVENQQAEKWDVHNFTMGFQRQVTDDAWEYLLLNGEESFNERGEPEWVFSRALGVDI
                     PLTSLTVIG"
     gene            complement(30059..30757)
                     /locus_tag="OPY25_002038"
                     /pseudo
     CDS             complement(30059..30757)
                     /locus_tag="OPY25_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
     gene            complement(30772..31176)
                     /locus_tag="OPY25_002039"
     CDS             complement(30772..31176)
                     /locus_tag="OPY25_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HCS0927657.1"
                     /translation="MAWTPRTLADALNNIAELDIDIENNESSLIIKMNDYGDLPLTVL
                     FTSQQIVIETYICPVNTIRDTAEFNLFLLRNQKVLPLSSVGIALVKQEEYYVAFGALS
                     LNSSLADVTLEITTLVENALDIAEITQVYSQE"
BASE COUNT         7793 a         8520 c         7753 g         7188 t
ORIGIN      
        1 cttttttaac ctactgcata gcacttttgg ttacgccatc tcagtttgca gacgcataac
       61 ctgacggtta acttcagaca tcacagacaa gtgctgcttg tctctcactt ttgggataag
      121 aatcttaccc ttatcgaact caaaagcgcc aacatccttg atatataacc gtccacggaa
      181 caggatcttc acgtacttcg ccacctgtag cgggttgtag cgttggaaaa ttttcattgt
      241 tgtctcctgc agagtattac gcccttgcgg tgccacaatc ggcccaacag ttttaaggcg
      301 caaattttaa tgccatatga ctatagacca tatctacgtc gtttccagtg tgcataagta
      361 tatttacctt ttgattacag ttattcagaa ttatctaaac atcagctcat ttttctcagt
      421 atatgccttc atttttcaca ggaagtgtgc acccgcccgc aaactggcat cccctttgcg
      481 ggaaaaagca tcaatcgcac atatgattaa ctgtcggccc aaagtggtcg gatcacctgc
      541 aaaaaaataa agaaggaatg accatgaccc tacgtaaaat tctggcgatg tcgtgtctgc
      601 tactccccat aatggcttgt gcgcataacc ttgaagataa ccaacgggtg ccgccggtag
      661 gcattgccga tcgtggcgaa ctgacgttga ataaagatga gtttagttat aaaaactgga
      721 atagcgcgca gctggcggga aaagtgcgcg tcctgctgca cattgcgggt cgaacgtcag
      781 cgaaggaaaa aaacgccacg ctgattgaag cgattaaatc agccaagctc ccgcatgaca
      841 gataccagac gaccacaatt gtgaacaccg atgatgcaat cccaggctcc ggtatgttcg
      901 tgcgtagcag tatagaaagt aataaaaagc tctacccgtg gtcgcaattt attgtcgaca
      961 gcaatggcgt ggcgcgtaac gcctggcaat taaaagaaga ggggtccgcc gtcatcgtgc
     1021 ttgacaaaga cggtcgggtt caatgggtga aagatggcgc gttaacccag caagaggtac
     1081 agcaggtggt cgacctgctg cataagctcc tcagtaaata gtcacccgga agccggggtt
     1141 aaggaacgat tcacgagggg tatagtccag cgtttttccc tgccagtcgt gaacgtgcgc
     1201 cccggctgca acggcaatgg catgacctgc ggcagtatcc cagacgctgg tcggcccaaa
     1261 tctggggtaa agctgcgcct gtccttccgc cacaagacag aatttcagcg aggaaccaat
     1321 agaggtagtc tgatgttcgc caagctgttg gagatattcg gtgagttcat catccgtatg
     1381 cgaacggcta atcaccacca gcggcgggcg ggcatcccgc acctgaatct gcttacgcac
     1441 cccgcactcc tctttccagg ccttaccttc cgccgcgtag tacatcactt tcagcaccgg
     1501 cgcatagaca acgcccaaca ccggcttgcc ctgctcaatc agcgcgatat tgaccgtgaa
     1561 ttctccattg cgcttgatga attctttggt gccgtcgagc ggatcgacca gccagtaacg
     1621 ctgccagtgc tggcgcactt cccaggcggg cggatcttct tctgaaagca ccggaatatc
     1681 cggcgtgagc gtgcgtaacc cttcgagaat cacggtatgt gcggcgatat ccgccgcagt
     1741 gactggagaa tcgtcctgct tgcgggcgta ctccatcggt ttggctccat cataaacctg
     1801 cataatggca tcgcccgcgt tccgtgcaag ctggcatact tgttctaaca ttctccacct
     1861 ctttatgacg ggggcgttaa ctcgttgttt tacttatacc cgatcgttaa gggttccgcc
     1921 aactgtgata ccgtcagcgg ttttgataat agctttcatg gcatgattca cctttctgtg
     1981 aacactcgca aaaaatcggc cggatggggc ggtttcgcct tcttctggcg acggtcggaa
     2041 cgataccggt ttcactgttt atcatcgcta tttttcacta tccggctttt ctattgcgtt
     2101 cttaaaaggt gcctctgatg attaagttta gtgcaacgct tctggctacg ctgatcgccg
     2161 ccagcgtgaa tgcggccacc gtcgatctcc gtatcatgga aactactgat ttacatagca
     2221 acatgatgga tttcgattat tacaaggata ccgcaaccga aaaattcgga ttggtacgta
     2281 ccgcaagttt gattcatgcc gcccgaaatg aagtcaaaaa cagcgtgctg gtggataacg
     2341 gcgacctgat tcaggggagc cctctgggcg attatatggc ggcaaaaggg cacaaagacg
     2401 gtgatgttca cccggtctat aaagcgctca atactctgga ttacgcggtt ggaaacctcg
     2461 gcaaccatga gtttaattat ggtctggact atctgcataa cgcgctggcc ggcgcgaaat
     2521 tcccttatgt taacgccaat attatcgacg ttaaaaccca aaagccgctc tttacgcctt
     2581 atctgattaa agagacgagc gttattgata aagacggcca cccgcacact ctgaaaatcg
     2641 gctatatcgg ctttgttccg ccgcaaatca tgatttggga taaagcgaat ctgagcggca
     2701 aagttaccgt caatgacatt acggaaaccg cccggaaata tgtgcccgaa atgcgcgaga
     2761 aaggcgctga tatcgtggta gtcattgctc actcaggcct ttctgccgat ccgtaccaca
     2821 gcatggcgga aaactcggtt tattacctca gcgaagttcc cggcgtcgac gcgattatgt
     2881 ttggtcacgc ccacgccgtc ttccccggta aagattttgc cgacatcaaa ggcgcggata
     2941 tcgccaaatg tacgcttaac ggcattcctg cggtaatgcc aggcatgtgg ggcgaccatc
     3001 tgggagtggt cgatctggtg ctcaataaca acagcggcaa atggcaggtt acgcaggcga
     3061 aagcggaagc gcggcctatt tacgacgccg ccgctaaaaa gtcgctggcg gcggaagaca
     3121 gtaagctggt cggtattctg aaagccgatc acgatgccac ccgcgagttt gtcagcaagc
     3181 ccatcggtaa atccgccgat aatatgtaca gttatcttgc tctggtgcag gacgatccta
     3241 ccgtacaggt ggtgaataac gcgcaaaaag cgtatgtgga acactttatt cagggcgatc
     3301 cggatctggc gaaactgccg gtgctgtccg ccgccgcgcc gtttaaagtt ggcgggcgta
     3361 agaacgatcc tgccagcttt gtcgaggtgg aaaaaggcca gctgaccttc cgtaacgccg
     3421 cggatcttta tctctatccg aatacgctgg tggtggtgaa agccagcggc aaggaggtaa
     3481 aagagtggct ggaatgttct gccggacagt ttaatcagat tgatattcac agcaacaaac
     3541 cgcaatcgtt gatcaattgg gatggctttc gcacctataa tttcgatgtc attgacggtg
     3601 tgaattatca aatcgatgtg tcacagcccg cccgctatga tggcgaatgc cagatggtga
     3661 atccgcaggc ggaacgtatt aaaaacctga cctttaacgg taagcctgtc gacccgaacg
     3721 ctacgttcct ggtcgccacg aataactatc gcgcttacgg cggcaagttt gccggcacgg
     3781 gcgacagcca tatcgccttt gcgtctccgg atgaaaatcg cgccgtgctg gcggcatgga
     3841 ttggcgcaga gtcaaaacgc gcgggcgaaa tccatccggc ggcggataat aactggcgtc
     3901 tggcgccaat ccacagcgat acggcgctgg atatccgctt tgaaacatcg ccaggcgata
     3961 aagccgcggc cttcattaaa gagaaagggc agtatccgat gaaaaaggtt ggtgtcgatg
     4021 atatcggttt tgccatttat caggtggatt tgagcaagta acgtgagtcc cgtatggcgc
     4081 tgcgtttatt cggcctgact ggcaggccga ataaagcgct agccgccatc tgataaacgc
     4141 tcccgctgcg ccaatacctg gggcaaattc agttctatcc agtccgccag cgcggcgact
     4201 ttatcactca cctgctcgcc aagcggcgtc aggctgtact ccacatgcgg cggaacaact
     4261 ggatatgaca cccggttaag aaatccgtcc tgttcaagcg cctgtaacga ctgcgccagc
     4321 atcttttcac tcacgcctcc catcttgcgg cgcaggtcgc taaaacggtg tgtaccgtcg
     4381 cgtaacgcga ccagaatcag tacgccccag cgactggtga catgttttaa cacctcacgg
     4441 gacgggcact gttcagcaaa gagattacct tcacgcaact gccgggaaag agtatgagcg
     4501 cgcattgata cttacctttt tgtacgtact tactaaaagt aagtttaggt ggtagcgtaa
     4561 taaaacacaa gaccaacact gaggagttca ccatgattgc tatcactggc gcaacaggcc
     4621 aactgggcca acacgttatt gaaaacctgc taaaaacgac gcccgccagt caccttgtcg
     4681 cgatcgtccg taacccgaaa aaagccgccc cgctcagtca gcgcgggatt gccgttcgcc
     4741 aggcggatta cgctaacgaa gctgcgctga ccaccgcctt acagggcgtt gataaactgc
     4801 tgctcatttc atccagcgaa gtgggacaac gcaccgcgca gcaccgcaac gtcattcagg
     4861 ccgtcattgc cgcgaaggtg aaattcatcg cctataccag cctgctacat gcggataaat
     4921 cgccgctggc gctcgccgat gaacatattg aaacggaaaa gatgctggct gagtcaggta
     4981 ttcctcacac gctattacgt aacggctggt atacggaaaa ctacctggcg agcgtccctg
     5041 ccgcgctgaa gcatggcgtc tttattggcg cggcgggaga agggaaaatc gcctccgcaa
     5101 tgcgcgctga ctatgccgcc gccgccgcgc gcgtcatccg tgaagagggt cacgccggga
     5161 atgtttacga gctggcgggt gataacgcct ggacattaag ccagttggcg gatgaactta
     5221 ctcatcagag cggaaaaaaa atcgtctacc agaacctgag cgaagtcgat tttgccgccg
     5281 cgctgaaagg cgcaggcctg cctgacggac tggcggatat gttggccaat tctgacgctg
     5341 gcgcggcgaa aggcggtctg tttgatgaca gccatacgct gcgtaaactc atcggtcgcc
     5401 cgacgacggc gctcacagaa agccttcgct ccgtactgta agtgttaaaa tttagttaat
     5461 ttatatggca tcctcataga ccttctctga taatgacgga acggtttatg aggagaatct
     5521 gatgattagc ggcgtgctat acgccctgct ggcagggcta atgtggggat tgattttcgt
     5581 cggcccgtta atcgtgccgg attacccggc cctcttacag tcaatgggac gctatctggc
     5641 gctggggctg attgccctgc cgattgcctg gttaggccgc acgcggttac gccagttgac
     5701 gcgcaaagac tggtccaccg ccctgtcgct gaccctgatg ggcaatgtaa tctattacgc
     5761 ctgcctcgcc agcgccattc agcgaaccgg cgcgccggtt tcgacgatga tcatcgggac
     5821 attgccggtc gtcattccgc ttttcgctaa cgttctctat agccaacgag acggcagatt
     5881 atcctggcta cgtttagcgc ccgcgctggc gcttatcggt tttggcctgc tgtgcgtcaa
     5941 tattgctgaa cttagccagg gattgtccga tgttagcggc tggcgctatg gttcaggcat
     6001 tgtgctggcg ctgatttccg tagcgtgctg ggcatggtat gcgctgcgca acgcccgctg
     6061 gctgcgggaa aatcccgaca aacatcccat gatgtgggca acggcgcagg cgctggttac
     6121 gctgccggtc tcgttaatcg gctatgcggc aacctgtctg tggctgagta tccagaaccc
     6181 gatgtttacc ctgccctttg gcccgcatcc cgcgctgttt atcggtctga tgatcgccat
     6241 cgcggtgctg tgttcctggg tgggcgcgtt gtgctggaat atcgccagcc aaaaattgcc
     6301 aaccgtgatt ttagggccgc tgattgtttt tgaaacgttg gcaggactgc tctatacctt
     6361 cattctgcgc caggaaatcc cgccattcct gacgttaagc ggcattgcgc tcctggtggc
     6421 gggcgtggtt attgccgtga gagcgaaacc ggaaaaagcg accgtcgttc cggtcacgga
     6481 acgctaatct catcctggct taaattatac gcaccccgaa agagttatag cctcgcctta
     6541 aagatgcatt taaaatacaa cttatattat tgcaaatgag gtaacggcta tggcttatcg
     6601 cgatcaacct ttaggcgaac tggcgctctc tattccccgc gcatcggcgc tgtttcgcca
     6661 gtacgatatg gattactgct gcggcggaaa acagacgctg gcgcgcgccg ccgctcgtca
     6721 cgacgtcgat attgacatta ttgaagcgca actcgcgcag ttggctgaac agcccatcga
     6781 aaaagactgg cgcgccgttc cgctggcgga cattattgac catatcgttg tgcgctatca
     6841 tgaccgacac cgcgaacaac tgccggagct tatcctgcag gcaaccaaag tggaacgcgt
     6901 tcacgcggat aagccaaacg tcccacgcgg cctgacaaaa tatctcaccg cgctgcatga
     6961 agagctttcc agccatatga tgaaagaaga acagatcctg ttccccatga tcaaacaggg
     7021 tatgggtcgc caggcaacgg gcccgataag cgtaatggaa agcgagcatg acgaggcggg
     7081 agagctggta gacgtcatca aacacgtcac ccaaaatgta acgccgccgc cagaagcctg
     7141 caccacctgg aaagcgatgt ataacggcat taatgagatg attgatgctc tgatggagca
     7201 catcagcctg gagaataacg tgctgttccc acgcgcgctg gccggggaat aatccatcgc
     7261 caataaacga tcctgaacgc atagacagga tcgtttattc tgaatcgact aacgcttttt
     7321 agcgagaggt gaatgcatta ttaataacct catatttccc ctcctcagtg accagataat
     7381 aaccgctctt gtcgatatgc gcagtatcca gcgtccgcgt tacgttacgc cgttgcccgc
     7441 tatctaccag cgtatcaccg aagaaataga gataacgatc gtcatgagca aaaacatcag
     7501 aaaatgaacc atcgggactt ttaaaccaca ccaatggtcc aataaggtcg ataatctgca
     7561 ctcccccatc gccgataaaa tagatctgtt tacccaccaa attagcgcca gctttcagct
     7621 gtacctgcgg atcaggcaag cgggtgatgg ttaataccct gtcgaccgga gagacatact
     7681 tcacctggta caatagatct ttgtactgtg ctaccgtcca attgtaatga atgggatgga
     7741 aatattctgg atcaacattg ggaatagtcg ctattcggca gtcatcgcct cggcgcgatg
     7801 cctctcgcgt catccatgtc accttatccc gctgtacatt aaacgtattg agacagtctt
     7861 tgccgaagta atagcgtttt acgcctgctt tgtcgcgata gagtaactgc acgccagcga
     7921 cccagcgcac aacatgaaaa gagttcggat cggcatcaat tgccacacca ttaacaaaaa
     7981 cctgcgtggc ggtacgcaga atagtgtccc acgggccagg attagatgta gtatcgcagc
     8041 tggtcggcga aaacagaata ttacgctgct cccaggattt aacgcccagg atggaatatc
     8101 cctgcgcact agccagccag cgtccctgaa agtagaggtt gcgcctgtct ttaagcacat
     8161 cgccggagtc gcgtaatttg atgttgccgc cgacctgctg caacgaatcc atatcgaccc
     8221 ttttttcacc atgattatca tctgtgcgct cgccgtcgaa gtaaagacta tctttatcag
     8281 cggcaaagcg tccatacgcc cgaaaagtcg ctgcatccac tggcggctta cccggtggat
     8341 tttgtacgat tttcccagcc cataaaatat gctggccgtc ggttagccaa taaaactgcc
     8401 agaaatcatt ttttattagc gatgaaaaag cggcgacatg aacaaaatca ttactcattt
     8461 ttccacggtc attatattca ttaacaatgc ggtcaggaac gtgccgtagt tgactaaatt
     8521 ttacctctcg aatttcaata tctttaaaat taatactata accataatct tcttcaacta
     8581 catatttcgt tccctgcccc cacggctgat agtgaaacaa agcatatgga atgtcggaac
     8641 aggccagagc taacactggt gccagcatta ataaaatcga taaacagaac tgttttattc
     8701 tcaacattgc gccatcctgc gctagtggta atcagaggga agcaaagaga taacgtcagt
     8761 gggcgctggt gataccgtcg tccactctgt taatatcggg ttatagctct gccattgatc
     8821 acgtgagatc tggcgatata attgcccatc cgcggacaaa gccagatggt agtaattata
     8881 ggtaactcta tctattttca gcgccggaag tttttcctgc gacgtaaaaa tgcgcagcac
     8941 cccctcgccc aacgcattcg tgctcacctg ataaatacga tccttatacc aaccggtgtt
     9001 cccgttcaga cgaaaaaaat actccggatc gacacccggc agggtttcca ctttacaact
     9061 gctcccggcg ttggttgcct catgcttcag ccatgtcacc tcacgcaggc caatattaaa
     9121 atagccgcag taccgactgg aattatcaat ctcatagtca tgcttaccgg ttttatcacg
     9181 ataaattagt acctcgccag gcatccagcg aatgatttga aacgtattag catcagcggt
     9241 aatgggtatg ccgttcacaa tcacccgttg cgccgtcgtc acaataaact cccttgccga
     9301 agtggaatcc agcctcaaca cgcgaaaccc atcggcccgc cccagccagc ggccttcata
     9361 atagagatta tttttatccc gcagcagatt ccagattttc gtctctgcca gagttgccat
     9421 atccacacgt ttttcacccg cattgctatc acgacgttta ccatcaaaat agagaccgtg
     9481 tttatcggcg gcaaaggcgc caaaagactg aaagctggca acatcaacgg caggctcatc
     9541 cccggtattc tggacgattt tgcctgccca caggataaag tgcccatcgc tgagataagc
     9601 gtgctgacaa atatgattgt cgtcgcagtt atggctgtcg ggattgattt ctattaacgg
     9661 gcgagggtct tgcgggtgag ataaatcggc aatacgccgt aaatgcgaat agctaacgtc
     9721 aggcagtcgg gagagaattt gcggttcgtc gtcggcggta taaaaaacgc cgtccttatc
     9781 ctgctgatac tgaaaatctg cgaacgcggg aacgggcagc agcaaaagcg tagcgcttaa
     9841 aatccagcgt cgaatggtca taattacagt ttgaaatagg agattaattt gttacttaaa
     9901 ccactttttc aacgtattat ccagcgcgag ccgccattat aggaattcat caaggcggca
     9961 cttaccgtca gcctgcaatt tacagctgcc cttcctgaag aaacgttttt cgcgtcattg
    10021 catcagcgga caaacactca tttcctgagc ttttcatctc catacgctat caaatgtggc
    10081 gagaaaaata gctcgttaag gagcgggaag cgacaaaatg gggcgtaaaa atgaagaaag
    10141 cgccccggcg ggtacgttat gcgcataccc cctcgcctaa gcgagaggga taaatccgtc
    10201 atttagccag tttgttctta cgcaggaaca gccagcccag acccaacgcg ataaaccaca
    10261 gcggcgtcac gatcagcgcc tggcgcgtat catcttccag cgtcagcaat accagcacga
    10321 acgcaaagaa cgccatgcag acccagcaca tcagcttacc gagcggcatc ttatagatgg
    10381 atttttcatg caggtgggga cgctttttgc ggtacaccag gtatgaacac agaatgatgg
    10441 tccagacaaa cataaacagg atggccgaaa ccgtagtgat catggtgaat gcgccaatca
    10501 cgctcgggtt gaccatcagc ataaccacgc cgcccagcag gcagatacag gagaaggtca
    10561 ggcctttcgc cggtaccgcg cgtttcgata gcttagcgaa cgcttttggc gccacgcctt
    10621 cttgcgccag gccaaacagc atacggctgg tcgagaagac gccgctgttg gcggaagacg
    10681 ccgccgaggt cagcacaaca aagttgatca cgctcgcggc ggcaggcaga cccaccagta
    10741 caaacagctc aacaaacggg ctcttatccg gtacgactga actccacggc gttaccgaca
    10801 taatgacaat cagcgcaaag acgtagaaca tgatgatacg gatcggtatt gagttgatcg
    10861 cgcgcggcag cgatttttcc ggatctttag tttctgcggc ggtagtaccg accagctcaa
    10921 tgcccacgaa ggcgaacacc gcaatctgga aaccggcaaa gaacccgcta atacctttcg
    10981 ggaaccagcc gccgtcattc cacagatgcg cgaaagacgc ttcaacgccg gtcggcgatt
    11041 taaagtgcat cgcaatcatc accaacccaa ccacaatcaa cgccacgatg gcgacgattt
    11101 tgaccatagc aaaccaaaat tccatttcac caaacatttt aacggtggcg aggttgaggc
    11161 ttagcagcag gaccactacc gccagcgagg cgacccaatc ggaaaggccg ggaaaccaga
    11221 actgcgcgta ggcggtaatc gccaccacgt cagccatacc ggtcactacc cagcaaaacc
    11281 agtacgtcca gccggtgaaa tatcccgccc aggggccaag caggtcggaa gcaaaatcgc
    11341 taaacgattt atattccaga ttcgagagca gcaattcccc catggcgcgc atcacgaaaa
    11401 aaagcataaa accgatgatc atatacacaa aaatgatcga cggtccggcg agactgatcg
    11461 ttttacccga tcccataaac agaccggtac caatagcgcc gccaatagcg ataagctgta
    11521 tatgacggtt tgtaagattg cgccgtagcg actgttcagc cggagcctgt tcgtcggctg
    11581 cgacttttac ctgatctacc atgtttttct tcctgtacct gtctgtgttg tgcgggctct
    11641 acggcctttg gtctatgata cgacgatcct gttatcagga ctcatcgata ttaggtaaga
    11701 atcggcggga tgaatactaa gattcaaata caatgttaat tttatgttta aaatgagtgt
    11761 tatatcactt tgataatgcg aattatctca caaaaataca cgtaacgacg ccatttgcaa
    11821 aataaaatat tggcatctgc tgaagtcagg gttgccggat aaggcgttta cgccatcatc
    11881 cggcaaaccc ggggcgctta cagaatttcc agcagttcca cctcaaacac cagggtgctg
    11941 aatggcggaa tagatgcccc ggccccacgc tcgccatagg ccagctcctg tgggatagtc
    12001 agttcccatt tggaacctac cggcatcaga gtcagcgctt caatccagcc ggcgatcacg
    12061 ccatttaccg ggaattcagc cggttcgccg cgcgcgacgg agctgtcaaa tacggtgcca
    12121 tcaataagct taccggtgta atgcacgcgt acgcggtcgg tacgcgccgg aatcgcgcct
    12181 tcgccctgcg tcagaacgcg gaactgtaaa ccagattcag tactgttcac accgtctttt
    12241 tcgcggtttt cttccaggta tttcacgcct tcggccgcca ttgctttgaa acgctcacga
    12301 cgcaccgcgt ccgcacgctc atgaatttca cgcagcgcac gatgcaccac atcaacagga
    12361 accgccgggt gtttaccttc cagcgcatca gcaatgcctg caaccagcgc ttcaggcaac
    12421 agcccttcaa gaccggattc gctgagctgc tgccctacct gcaaaccaat gccgtagctc
    12481 gcttgcgctt caatagtgtc aaaagtcggg gtggccatta tttttccttc atcggatatc
    12541 aaaaaagtag cgggcagcat aacagccacg cttcttctgg taaaactttg tctcagggag
    12601 gatgacaaat cgcagggaaa aagaaacaat agattatccg tattgatgtc acgaaagcgg
    12661 atagcactac cagtatcata gcgttagcca tctatactct atgattaagg aacgagatgc
    12721 ggagcaggag gtaaaccatg cccgggcgct ttgaattaaa accaaccctg gcgaaaatct
    12781 ggcacgcgcc ggataatttt cgcatcatgg agccgctgcc gcctatgcat cgtcgtggca
    12841 ttatcattgc cgctatcgtg ctggtgatcg gcttcctgct gcccgccagc gagaccagcg
    12901 actcgcctgt cgtcacgcgg gaagcgcaat tggatctgca atcgcaatca cagccgccga
    12961 cggaggccca gcttcaggcg caactggtcg cgccgcaaaa cgatccggat caggtggcgc
    13021 ccgttgcgtc ggaacctatc caggaaggcc agccggaaga acaaaaccag ccgcagacgc
    13081 agcctttcca gcaggatagc ggcatcggtc aacaatggcg ctcgtaccgg gtagagcctg
    13141 gtaaaactct ggcgcaactg ttccgtgacc acggactgcc cccgacagac gtttatgcaa
    13201 tggcgcaggt agaaggcgct ggcaagccgc tgagtaacct caaaaatggt caaatgatta
    13261 aaattcgcca gaatgccagc ggggtggtga caggtttaac gatagatggc gataacggtc
    13321 aacaggtgct gtttacgcgt cagcctgacg gcagttttat tcgcgcacag taacgccggc
    13381 tgcgccttac cccgtctata ccctattcgt tcaggtgaag cattaccgct tcaccttatt
    13441 cacccaccaa atccccgaac acaccagcac cagcgcaatc atgtatttcc actccaatat
    13501 attctcgccg agaaaaatag ccgaaagagc cgcgccagaa accgggatca gaaagttaaa
    13561 cggcgcaatc atccccacgc gattatattt gagtaaaatg ttccatagcg caaaagcgac
    13621 cgacgagagc agcgtcaggt agactaaaat cgccaccgac gagaagccat gtatcgtcag
    13681 cgtaccgcca aaaacgtaac cgccaatgac cagtaccaga ccgccaatcc ccaattgata
    13741 gccagtcatg accatcggat cgaccgtctg cgagagacgt ttgccataca atgtggccgc
    13801 agaaagaata aacgcagcca gcaccacgga gccttctccc ggcagattaa agctgaaatc
    13861 caggccgttg ctgacgttca ccaccatgac gcccgcaaag cccagaatac agccgagcgt
    13921 tttgttgtag ctcaatcggt cgttctgata aataaagtgc gccagcaata cgctgaagaa
    13981 tgtgcctgtc gcgttcatga ttgagccttt cacgccggag gtgaacgcaa ggccgatata
    14041 gaaaaagaga tattgcagcg acgtctgggt cagacctagt aacgttaact gagcaaactg
    14101 gcgcggacga aaccgaccaa tcggtttacg ctgaagcagc gcgaacagta gtagcaaccc
    14161 acccgcaaac aaaaaacgat aaccagcaaa aacaatttta gaagggatat cgtcggtggc
    14221 tatctgaaag aggtcataac cgcttttgat ggctggataa gcgctgcccc atagcaggca
    14281 acaaaatgcg gcacacacat aaacgacgtt tttgcgggca aacggggagg cctggcgttg
    14341 ggtatccatt ctttcaccaa gaaattaaaa taatgtttta tttttaatta tcgcgaaaag
    14401 agggggagat agccagtcga aaagcgatgg agttaaaaaa gcaaaacgcc ggcgctgggc
    14461 cgacgtttcg ttgctagcaa aaacgagaat gactgattac tcagcaacca cgttgatgat
    14521 aacttttgcg aatacttcgc tgtgaacctg gaagttcact tcgtgttcgc cagtggtacg
    14581 cagaacgccg ttcggcagac gaacttcgct cttagccacg tcaacgccag ctgcagtcac
    14641 agcgtcagcg atgtcgcgag taccgatgga accgaacagt ttaccttcgt cgcctgcttt
    14701 agacgcgata gtaacggttt ccagggcgtt gattttctct gcgcgtgcat ttgcagcagc
    14761 cagaacgtca gccagtttag cttccagttc agcgcgacgt gcttcgaagt attcaacgtt
    14821 tttcttggta gccggaacag ctttaccctg tggtaccagg aagttacgag catagcccgc
    14881 tttaacgtta acctgatcac ccaggctacc caggtttgct actttatcaa gcagaataac
    14941 ttgcattacc ttatcctctc aaagtcgtat taatggaccg tgaccgatta ctgatggcga
    15001 tcagtgtacg gcagcagaga caggtagcga gcgcgtttga tagcgcgagc cagctgacgc
    15061 tggtattttg cacgggtacc ggtgatacgg cttgggacaa tcttaccgct ttcggtgatg
    15121 tagtttttca gcgtagcgat atctttatag tcgatctctt gaacgccttc cgcggtgaaa
    15181 cggcagaact tgcgacgacg gaaataacgt gccatatggc tagtctccag aatctatcaa
    15241 ttcaatctgc tcggcatgca gaaccatttt gctcagaccg ttctttgcct tgtggcaaga
    15301 aataaacccc tgaacggtta tgcggctgcc gaccgttata ctgtgagtaa tggcctggtt
    15361 ttcgtgtccg ctaacaataa cgggcatttg gcaccacgcc tgccggtgaa agccggcttc
    15421 ctcttgcaca gaacgatgct caagcacgaa ctggcaatgc ggaattcctg atggactgac
    15481 ctttcgaagg ggggccctgc acacggtgcc ggacaacgtc agacggttgg tcatcagaaa
    15541 ttactcttca gaatccccag cttcagcatc atctgcggtt tcgttagcga aatcatcgcg
    15601 acgctcacgg cgctcgtctt tcgctttaac catcggagat gcttcggtaa cagcgtgctt
    15661 agtacgcata accatgctgc ggataacggc atcgttgaag cggaaggtag tttccagctc
    15721 atcgatcact tcctgcggcg cttcaacgtt catcagaacg tagtgcgctt tgtgcagttt
    15781 gttgatcggg taagccagct gacggcggcc ccagtcttcc agacggtgga tcttgccttc
    15841 tgcgccagtg atggcagcag agtaacgctc gatcataccc ggaacctgtt cgctctggtc
    15901 aggatggacc ataaaaacga tttcgtaatg acgcatcgaa ttgctcctta cggattattc
    15961 agcctcctgt ctgggtcagc cgcggcccat ggaggcaagg aacgtgttaa aggtcggctg
    16021 aaaaatgacg cgttataata ctggcgcctg cgggcaaact caaggtgatt gtacaattat
    16081 ttatcgtgcc gaacgtaacg cctgtcccgt cacattttgc tgctgagata ttaacttcat
    16141 atcgcatgcc actataaacg gcctgttgcg gcagaaaaat tgacactgtg gtcagcgtac
    16201 ttttttgcca cacagggttt cttaaacata gcggcataca tcaacgggtt gttaatcagg
    16261 taaaaaacga caatgcgata attttttgaa caacagcatc agaaaaggtc gccatctctg
    16321 cggctggtta tggttaaaat taaaccagaa gcgattcact aaagggggat atcgccaacc
    16381 agaccgcgct gctgaggagg tactctatgc gagcccggat aatgttattt ctggctgcgc
    16441 ttttgcctgg cataacggca acggcagcca tcgagttaaa taatcaccag gccacaaata
    16501 tggatgatgt gcgcagctta ggcgtgatct acatcaacca taacttcgcc acggaaagcg
    16561 aagccaatct ggcgctgaat gacgaggccg acgcgcgaaa cgcaatgtat tatcacgcca
    16621 tacttatccg ggaaccgggt agcaacggca acatacacgc cagcgcgaat atttatcgct
    16681 aacatcagga aaaccaacga aaaagccata gttgatttgc ccccctgaac agggggcttt
    16741 tttcgcggaa agatggctcc ggaattagac ctgtgacatc ccgataatat tcacattccg
    16801 gagctcatac ttcacttctg cccgtaatac gcattcgggc catgcttacg catgaagtgt
    16861 ttattcatca gataatcgtc gatggggttg aggccagggt taatgccgcg cgcaatccac
    16921 gccattctcg ccacttcttc catgacgacc gcgttatgta ccgcatcgtg cgcatctttc
    16981 ccccaggcga acggcccgtg ttgatacacg acaatgcctg gcgtatgcag cggttccacc
    17041 tcgcccagcg tttcgatgat caccttgccg gtgttcagct cgtactcgcc ctgcacttct
    17101 tcttcgctta acgccctggt acaaggaata tcgccaaaga aatagtccgc gtgcgtggta
    17161 ccgagcgctg gaatagccat ccccgcctgc gcccatgccg tggcgtgggt tgaatgggta
    17221 tgaacgacgc cgccaagcga cggatagcgt tgatacagcg ccagatgggt agcggtatcg
    17281 gaagaaggac gataacgacc ctccaccact ttgccatcca tatccaccac caccatgtca
    17341 tctaccttca tggtttcata ggcgacaccg cttggcttaa tcaccaccag cccgcgttcg
    17401 cgatcgatag cgctgacgtt gccccaggta aacgtcacca gtccataacg gggcaaatcc
    17461 atgttagcgt caaatacctg ctgcttgagc ttttgcatta tgccgcctcc accatgcctg
    17521 ctttggccat gcgcgctttc acccagtcac gcgctttcgc tacctctgcc gccgggttct
    17581 ctgctgtttc gctccacatc tcaatcagat agggcccgca atagccactc tgtttgagcg
    17641 tttcgaagca gcgttcgaaa tcgacaacgc cttcgccaaa cggcacattt ttgaacacgc
    17701 cgggtttagt atctttgacg tgtaccgcga cgatatgccc gattcccgcc tgtagctcca
    17761 tctgtacgtc gttatcccag gcagacagat tgccgatatc cggatagagc tgaaagcacg
    17821 ggttattgag gtagtgagca tagcctagcg ctttactgat ggaattcatc aatgggtaat
    17881 ccatgatctc catcgccagc gtcacctggg cgcggctggc catatcaacg ctctctttta
    17941 acccatcgcg gaagcggcaa cgcgtttcgt cgttggcctg ctgatagtaa acgtcgtacc
    18001 ccgccagttg aatgacgcga atcccgacgt cctgcgcaaa ctgaatcgct ttacgcataa
    18061 tctccagccc ctgcgcccgt accgcgtcat cttcgctacc gagcggaaaa cgacgatgcg
    18121 cgctcagaca catggacggc acacgcacgc cggtttcagc aaccgcgctc accagcgcca
    18181 ggcgctgctc gcgactccag tcgagccgcg ccagtcgggc gtcggtctcg tccaccgaca
    18241 tttcaacgaa gtcaaaaccc agcgttttcg ccagccgcag gcgttccagc cagcactccc
    18301 cggcagggag cgctttttca tagatgccga gcggaatttg tttcgacagc atagccgctc
    18361 cttagcccca cagttgggca atggagcgtt tgaactgccg tgcggcttct accggcgatt
    18421 cagcatcgcg aatgctgcgg ccagcaataa agacatggat cggaatgcct ttgaacagcg
    18481 gcaggtcttc cagcgccagt ccgccggtca cggtcacttt aaagcccata tcggacagcc
    18541 gtttaatcgc agtaatatcc gcttcacccc acgccacgcc tgcggcctgc gcgtcgcagc
    18601 tgcggtggta aaccacttgc tgaatgcccg catcgcgcca ctgctgcgcc tgttcccagg
    18661 tccagtaacc ggtcagttca atctgcacgt cgccgttaaa ctcttttgcc acatccagcg
    18721 cgcctttcgc ggtgttgata tccgcacagc aaatcacggt cacccagtcc gcgttggctt
    18781 cgaagcacat acgagaaagg attttgcccg catcggcaat tttggcatct gccagcacga
    18841 ttttgtgcgg gtaaagcgct ttcagatcgc gaaccgcacg cacgccttcg cccacgcaca
    18901 gaatggtgcc cacttcgata atgtcgactt cttcggcaat caggcgagtg gtttcgtagg
    18961 cgctatccat agtctggttg tccagcgcga cttgcaacat cggtaatgac atgttcaatt
    19021 ccttcttaag ctgccgcgtt ggtgcggtca atgagatcca ggacttcctg cgcggtacgg
    19081 caggcgcgta aacggtcaaa attggcttcg tcttcaaaca ggttgacgat ctgcatgatg
    19141 cccacttcct ggtgagtgtt ggcatcaacc gccgccatag tgatcagaat atcgaccggg
    19201 tcgttatctt cgtggttgaa ctccagcggc tttttcagcg tcaccagtga gaaaccggtt
    19261 ttcttcacgc cctcttccgg acgcccgtgc ggcattacca gccccggagc gataacgaaa
    19321 taagggccga actgttccac gccatcgaga atcgcctggt agtaacgcgg ctcgacaacg
    19381 tctgccgcca ccagcaaatc cacaccaatt tttacggctt cctgccaggt attagcttca
    19441 gcctgcaagc ggatagaatt attctccgcc agcgaatcac gtaatttcat gttgcgtcct
    19501 tacttcacgt cctgtggaaa atgcgctttg atcacttcca gcaatttcgg gccgaagtct
    19561 gcgggcgata gcatgttgcg cacgccaacc acatatttgt tgcccgtcac ggtgatttcg
    19621 cctgcaatgt gtgtggaagc gatgatgata tccgcgccgc tcaactcgct tttgtactcg
    19681 ccaaccgcgc agctgtttac cgtgtggtcg atattggatt gggttaaaaa ctggtccact
    19741 ttcattttca tgatcatgga actgccctgt ccgttgccac acacagccag aatacgtacg
    19801 gtcataatca aaactcctta ttaagcagac tgttctgcca gttgtttttc tgcatcttct
    19861 tctgcgcgca gtgcgcggcc agcgaagaac atataagcca gtgcaattac aatgatgacg
    19921 gccataaagg cgataccgat ggagaagaag ccctgcatca tcggcggcgc cagaatcgac
    19981 cagtccgcca tacccatcca ggcgctcatc cccgtgagtt tcaccgccca gacgcaacca
    20041 aagatttcaa tcatccccat caccagacaa attttcagcg ccgcacgcca gccgccgaag
    20101 tggttagcga acacgccgat agtggcgtta gagaagaaca tcgggataaa gccaggaata
    20161 atcaggatcg aggagccgca ggcaaccagg atgccaaccg caatcagctg accgatggtg
    20221 ccccacataa agccccagac tacggcgttc ggcgcgaagc tatagatagc cgcacagtca
    20281 atcgccagaa ccgcacctgg gatcaggcgc tgggagatac cgttaaacgc ttcagagagt
    20341 tccgccacaa acatgcgcac gccctgagtg atgatgaaga tcgccaccgc aaaggagaaa
    20401 ccggtttgca ggatgtagac cgtccagtgc actttgcccg ccatcgcctg cacggtgtcg
    20461 ataccgaagg agagcagaat ggcaccaaag aagatggtca ttacaatcgc cgtagaaacg
    20521 atgttgtcgt ggaagatatt cagccagccc ggcaatttga ggtcttcaac gctttcctct
    20581 tttttgccca ggaacggcgc gactttatag gcaatccagg aagcaaactg ctgctggtga
    20641 ccaatggaga aaccgcagcc gtccgtcact tcttgggtgg gcttatacat catgttggaa
    20701 gtgatgcccc agtacaggga aaccagtatc gccgtgcaga taatggtggt ccacatggaa
    20761 tagccgaaga tatagaaaga gaccgcaatc agccccgcct gctggaacat gatgtgcccg
    20821 gtcaacatga tggtgcgaat accggtaatg cgtcgcaata agacgtaaca aatattcagc
    20881 gccagcgcga gcaacaccgc gtagcctacc caactatacg catcgcccat ccgttcgatc
    20941 gttgccatca tcgaagcata ggtatcggaa atcgcgccgt tgataccgta gacctcagac
    21001 attttcgcca ccaccggttt aaaggtgctg gtcagaatgc cggacccggc ctgtagcagc
    21061 atgaagccaa tgatggtttt gatcgtccct ttgatgatca cgctgacgct tttgcgcaac
    21121 aggatatagc ccaggcaggt cacaataccc agtaatagcg gggcattagt cattacctga
    21181 ttaaagaaaa tggtaaagat gttgtagagg atctccataa cgatctccgg cagataaggt
    21241 tgctgagtca caggcgctca ggataatgtc ccttcacttt aattttcaaa agtaatcaca
    21301 acaagattaa atttgattaa atgtgacgta gcgcgcaaat aattagcaca cttaatacat
    21361 ggtttactta taggtaactc attttttcat taaaataagt aaaatcataa agatgccaac
    21421 attcacatga cgccagacaa gattaaatct tcttctgact gcgttctctc ctgccaaaaa
    21481 gtcaaaaaat agcccattgc cttcttgaga aaatagtgtc aggattaatc aaaacaaatc
    21541 acgttttgaa ccattttgaa caaacatgaa ggtaaatgcg atgagtaaag tacaaagcat
    21601 cacgcgtgaa tcatggattc tgagcacgtt tccggagtgg ggaagctggc tgaacgaaga
    21661 gattgaacaa gagcaggtcg cgccgggtac gttcgctatg tggtggctgg gctgtaccgg
    21721 gatctggcta aaatctgaag gcggcactaa cgtatgcgtc gatttctggt gcggtaccgg
    21781 taaacagagc cacggtaatc cgttgatgaa aaccggtcac cagatgcagc gtatggctgg
    21841 cgtcaaaaaa ttacagccta acctgcgcac cacgccgttt gttctcgatc ctttcgctat
    21901 ccgtcagatc gacgccgtcc tggcgaccca cgaccataac gatcacattg acgtcaatgt
    21961 cgcggctgcc gtaatgcaga attgcgccga tgatgttccg tttatcggcc cgcagacctg
    22021 cgtggattta tgggttggct ggggcgtgcc gaaagaacgc tgcatcgtgg taaaaccggg
    22081 cgatgtcgta aaagtgaaag atattgaaat tcacgcgctt gatgcctttg accgcaccgc
    22141 attaatcacc ctgcccgccg atcagaaagc cgctggcgta ctgccggacg gcatggatgt
    22201 acgcgcggtt aactatctgt ttaaaacgcc gggcggcaat ctctatcaca gcggcgattc
    22261 tcactattcc aactattacg cgaaacacgg caacgaacat caaattgatg tcgcgcttgg
    22321 ttcctatggc gaaaacccgc gcggtattac ggacaaaatg accagcgcgg atattctacg
    22381 catggcggag tcgctgaaca ccaaagtggt gatcccgttc catcacgata tctggtcgaa
    22441 cttccaggcc gatccacagg agatccgcgt gttatgggaa atgaagaaag atcgcctgaa
    22501 gtatggtttt aaaccgttta tctggcaggt tggcggcaag tttacctggc cgttggataa
    22561 agacaatttc gaataccact atccgcgtgg ttttgacgat tgctttacca ttgaacccga
    22621 tctaccattc aaatccttcc tgtgagtcga tatcatgccg ggattacccg gcattttttc
    22681 catttacttt agtatttcca ggctatttca aatatcatct tttcaaatca atttgtatcg
    22741 gaatagctca tgactgaagc acaaagacat caaatactgc tggatatgct ggcacagttg
    22801 ggctttgtta ccgtcgaaaa cgtgattgag cgtctgggaa tctccccggc gacggcgcgc
    22861 cgcgacatca acaagctcga cgaaagcgga aaacttaaaa aagtgcgcaa cggcgcagag
    22921 gccattaccc aacagcggcc ccgctggacg ccgatgaatc tgcaccaggc gcaaaaccac
    22981 gatgaaaaag tacgcatcgc gaaagcggcg tcgcagctgg taaacccggg tgagagcgta
    23041 gtgattaact gcggctccac cgctttcctg ctggggcgcg aaatgtgcgg gaagccggta
    23101 cagatcatta ccaactatct gccgctggcg aattatctga tcgatcaaga gcatgacagc
    23161 gtgattatca tggggggtca gtacaacaaa agccagtcga ttaccctgag cccgcaggga
    23221 agtgaaaaca gtctctatgc tggccactgg atgtttacca gcggaaaggg cttaactgcg
    23281 gatggcctgt acaagaccga tatgctaacc gccatggcgg aacaaaaaat gctcagcgtc
    23341 gtcgggaaac tggtcgcgct ggtcgatagc agtaaaattg gcgagcgcgc gggaatgctg
    23401 ttcagccgag ccgatcagat cgctatgctg attaccggca aaaatgccaa tccgcaggtt
    23461 ttgcaacagc ttgaagccca gggtgtaagc atactccgcg tttaaagatg ctgtcggaaa
    23521 aacgctaccg tcgccgacaa cgcttctggc gtaatgcgat gccgcacgcc tgcggcccat
    23581 aaacaggtca catgcttatc cagcttcgcc ccggcgagtg cctgctggag ccggaaggtt
    23641 tcgatagcag gcaccacgtc atcctcctga ccatgccaca acagaagcgg cctgtcggcc
    23701 agtcgctcta actgatgtgt gacttcccat tcacgtagcg gcgcgatgat attgtcgaat
    23761 tccgcctgct gtgccgggtt ctgcggggat aacggcggga aaagcgtccg ggcaagcccg
    23821 gtaaaatagc ccgaccccat taaactggcc ccgcatttta cctcacggtg acgcgtcata
    23881 atgcccagcg ccgtcatacc gcccatggat gcgccgccca ccgccaaccg cccgtcaagt
    23941 agccagtttt ccgcctgaat cgccgcacgt aacgtcgtaa attcctgcat gttttggtgc
    24001 agaatctgcc agaatcggtg tatccgtccc tgtgagtcgc cgccgaagcg agcgccatgc
    24061 tccggcgcat ccggcatgac tacccggaat cctgcctgtg ccagggcaac ggcaaaataa
    24121 ctataaacca ggctggagga ggtgaagcca tgatagaaca ccacacaggg aagcggcacg
    24181 gcgcgtttcc cttccgggaa ggcatgtagt acgacgcctc cggctaattg tcgtgtttca
    24241 atcgctatca ttattctctc ctttttatcc ggtatgccac ggagaaatac ttaacgcaag
    24301 tttatggata gcgcaataat tcataatgtt tgagaactgg gttacgcttt cgcaacgttt
    24361 tcattcgaaa atcgcgtgac aggtaacact tcgggaacat tccccctaaa gggaaatcaa
    24421 taaggcatta cactatgatt atcaggaaac gagatagagt tatgcgtcgg tttgctccat
    24481 tgatagcagc gctgttatta agcgcgtgta gcatgctgca gggtacgccg caacctgcgc
    24541 cgcctgtcgc cgatcacccg caggaaatcc gtcgcgatca aacgcaagga ctacagcgga
    24601 tggggaccgt aagcgcgctg gttcggggtt ccccggatga tgcaatagat gaaatcagag
    24661 cgaaagccgc cgctgcgaaa gccgattatt acgttatctt aatggttgat gaaacggttg
    24721 taaccggaca gtggtattca caagccattt tatatcgtca ataacagtag attgattttt
    24781 agtcagtttt acattgcttt gcgcccctat gcgtttacct gtgcacaata aacaaacagg
    24841 tttaccgtga tggagcgtcc tgttaaatgc ggggtatgta ataaggagct gacgatgaaa
    24901 caagaacttg ccttatcctc actgctgctt tctgccggac tggtgagtac gacggcacag
    24961 tctgccgaat tcgccagtgc tgactgcgta acgggtctga atgaaatcgg cctgatctcg
    25021 gtcagtaatg ttgcaggaaa cccacaggat gtggagcgga ttatcgccct caaagccgat
    25081 gaacagggtg cgtcctggta cagaattatt caaatgtatg aagaacaaca gtcgaataac
    25141 tggcgcgtac aggcgatact ctatgcctga tgccgcgtgg ctcgcgccgg atggcatgta
    25201 ctacaggcca aacgttaccg cagtcccccg gtcgccctta acagtaaatc attttgcacc
    25261 tgggcaggca gcggcatttc gccgcgtgta tccagcatca tctgacacca cgcttgcgcc
    25321 agcggcggcg aggcatgacg cagcatttcc gctccgcacc ccagcaagaa aagctgctgc
    25381 gtaatctctc tgcccattgc ttcgtccggt ttgcgtaaac gttgctgtag ctggcgtacc
    25441 gcgcggtcgt aatggcgatc ctgacctttg acttccgcaa aagcttcact caatacgtca
    25501 tagacgccgt gttgttttgt cagcacccga agtacatcca gacacatgat attgccggaa
    25561 ccttcccaga tactgttcac cggcatttca cggtacaggc gcgggagttc gctctcttcg
    25621 caatacccca tcccgccgag aacctccatc gcctcagcca caaaagggat tccctgctta
    25681 cagatggcga atttcgccgc tggcgtgaat aatcgcgccc ataatgcctc tttcgcctcg
    25741 cgacgttgct cccaggcgcg cgccagccga aacaaaagcg ccgtctgccc ctccaggcat
    25801 agcgccatac gacttaaggt ttgtcgcatc aacggttgtt cgatcagcgg cttaccaaaa
    25861 gcctgacgct gatgagcatg gtaaatggcg actgaaaatg cgcgccgcat taagccatga
    25921 ctcccgagcg cgcaatcaag acgcgtcata ccgcccatct ttaagatatg ccgaatccct
    25981 tcgccctctt ctcccagccg ccagccgacg gtatcctgaa actcgacctc ggcgctggca
    26041 ttagatcgat taccgagttt atctttcagg cgctcaagac gaacagagtt ccgttgcccg
    26101 tctggcagga aacgcggcac aaagaaacag gatagtcctc cttttgcctg cgccagcacg
    26161 aggtgcgcat cactttgcgg cacagagaaa aaccatttat gtcccaccag ccgatatgaa
    26221 tcatccgcca gccgctccgc gtgggtcgta ttactgagta cgtcagatcc gccctgcttt
    26281 tccgtcattc ccatgccgat gagcaggccc cgtttttgcc cgcccggcag caaatgcgaa
    26341 tcgtagcgat cgctgcgcag cggcgccagc cagtcatgga aagtggcggg aagcatctgc
    26401 aatagcaacg gcgtcgcggc aaaggtcatc gtgacaggac agagtgttcc cgcttctacc
    26461 tgagcatgta atacaaaacg cgccgcccgg gcgacaaaac ttcccgccct tgcctcttcc
    26521 tcccaggcca ggtaatgtac cctattagcg caaagcccct gcatcaacag gtgccaggcg
    26581 ggatgaaagc gaacgtcatc caggcgctgt ccctggggat cgtaacgcag caactcagga
    26641 ggatgcgcgt tcgccagacg ccccagttcc agtgattccg ccgttcccag ttgttggcca
    26701 atgctggcga gaagatcgct atcccatccc gcgccttccc gggaaaccgc ttcacacagc
    26761 gcgccatcag acaggaataa gttactgtta ttgagcggag caggttgatt aaagacggta
    26821 tgtgtttgcc aggacatggt gtctccctcc ttcaatggcg ctgaagtcaa gtatggtcat
    26881 gactgcgcca ttgacgccgg agcaagatca caaaagtatg attaaccggc aatataatgt
    26941 gggacgaaac gggaagtgtc tttggtaatt agcgtattgt cctcgcgaat ccccattccg
    27001 gaggcttcat cgtcaatgat ccaactgcca atcagcgtat agctatcgcc aaagcgcggc
    27061 aaaggctgaa acgcctggta aatcatcggc tcgtcagcgt agtcgccatc ggcatgatcg
    27121 ataacatttt gccgctcgtc aaaaatcgtg acgttgccgc cttcacgtga ataaatcggc
    27181 ttccgtacgc tactttcacc tggcgctgcg agcgattttt cgccctcaaa ccaggccggc
    27241 agaagattcg gatggccagg gaaaaagcgc cacaataacg gcaacagccc tttgttactc
    27301 agaatacttt tccacaatgg ctcaatccat tgctcacgac gttttcgcaa tagcgggccg
    27361 ttgtcatcgc gcatcatcca ttccagcggg tagagcttaa aggcgcggcg aatcacgtta
    27421 tcgtccagat cggtcagcac gccgcctacg ccaagcccca gttcttcaat atagataaat
    27481 cgcgtttcct ggcccgcctg ctgcgcgcaa tcctgaaggt acagcaccgt cgtacgatct
    27541 tcgtcggtat cttcacaaca gcaaaagtag agcggttccc gactgtacag ctcgctgaag
    27601 cgggcgatca gccgctcctg tatcgcgttg tattgatcgg catcacgcgg gatggcgccg
    27661 ctacgacgag catcctccag ccatagccat tgaaagtagg aggactcata gagcgatgtc
    27721 ggcgtatccg cgttgtattc cagcaattta accggatctt tgccgcacca gacgaaatcc
    27781 atccgcccgt aaagcgaagg atcgcggctg cgccaacttt cggcgatgac atcccagtac
    27841 aatggcggga tcgccagctg ctgcatgatc tgctcatccc ggacggcccg ctcgacaacc
    27901 tccagacaca tctgatgaag ctctgcggtc ggtttttcga tctgttcttc aatttgccgt
    27961 aatgtaaaac ggtaggcccg gctttcatcc cagtaaattt cgttatcgat aacatgaaag
    28021 tcaaaaccgt gatcgcatgc gatcttatcc agatcccggc gtaccggtac gttatgtcgt
    28081 agcatggtta gcctccccag tgcccgcggg cgctggaaga acggccatag ccgccgcggg
    28141 agacggtgga cgctttccgt atgatataac cagggctggt cacggtatcg cttttccctg
    28201 tgccgctgcg ccacgcataa tcgccggatg tggtgcgcca gacgggacgg gagacgtaag
    28261 atgaaccgcc gctgctatag atgtattgtt catcacggtt ctgacgaatc gcgcggctga
    28321 gtaaaaagcc gcttaatacc ggaacccagc tccgctcggt gatatcaaag tagcaatcgc
    28381 caaactgcga ctgacagctc tcctgcgtca attgcttagg cacattagcg taaaattctg
    28441 ttttcgcatt attccagccg tcagcgcaaa cgctggcgct attgccatcg tcaatacagt
    28501 cgttcaccgt ggcgtaaaac gtcccatcgc cgtcgttgtc actattgctg ccgtcaccgt
    28561 accctttcag gagaaaaaag gccgctccac ccataatcgc cagcgtcagg tattttggcg
    28621 tgtagcgatt tcgttgccgc tcaaagggat tgaccggttc ggctatccgt cttattgccg
    28681 aatggcctac gccggatgtg cttctggatt ttcgtttttt tgccatgatc ttccgttacc
    28741 atgtcataca ggcagcgtta aaaataccgc cagccagcgc tgcggttccc ataaatagcc
    28801 ccgccgccac gttgtgatga ataatttttt cgctcagcgt aggcatgtat aaccttacgc
    28861 aaccataaat cagcagctga atcaccagcg caatgccgcc ccaggcaaaa tagtccggga
    28921 tgctgactga gtttatcgcc gcgctggata aggggatgac atagcccagc aacgtaccac
    28981 taaaggccag cgatgccgca gtattgttat tttttatcaa ctgccattca ttatgcggcg
    29041 ttatctttga gtaaataaaa agaaatacaa tgatcattgc cgcgccaata aaaaaatagg
    29101 cgcagaaagc cagtaatgcg tccagtatat gcataatttc cctgtatgtg cttaaccaat
    29161 aaccgttagt gaagtgagag ggatatccac gccgagggcg cgtgaaaaca cccattcagg
    29221 ctcaccgcgc tcgttaaatg attcttcccc gttcaataga agatactccc aggcgtcgtc
    29281 cgtcacctgg cgctggaaac ccatcgtaaa attgtgaacg tcccatttct ctgcctgctg
    29341 attttcaacc ttttccagca tgtagacagg ttcaatattg cccggctctt catggttaaa
    29401 aaagcgctgc cagcgccgtt cttgccagtt gagcgtcatc ggccctattg ccgctggcgc
    29461 aatggctgaa cgccagtgac gttcctcgtt aataccgaaa ctttcctcat atacaaaaag
    29521 tttgatgtca tcaatgtcgt caacatccgt gccgccagtg gtgttaattt gtagaaactc
    29581 atcgccagag gtgtagtagc gaaaaatctg actgccgccg cctaaatcta tgcgactcgc
    29641 tgccgcgaca gtgtattttt cacctggtag cgccaccagc aacgacgact ctagtagccg
    29701 gaatgccagc gtatccagcg tgaaaccggc gttaagatgt aatcctaatg gtccgcgaat
    29761 cggcgctggc gtgcttgttt taccgagcaa acgctgaaaa aattgcatca taggggaacc
    29821 tctatctctt gccatgcgac ctcttcagac agaatgcgat tgtcgttggg cataatgtca
    29881 tttgagatcg cgcattcatg tgccgtctcg tatgaaagcg acgaagctca gcacggtagc
    29941 gcgctttcgc gctacagata gcaaagcaga tactgcccga taaacaggcc cagcaaagcg
    30001 ggccaggtca gtctggacaa atgacgctgg caggttttga ccatccacgt aaagagcatt
    30061 attcgccttg ttgacgctgt aaacgcgcca acacatcctg agcattgctt ttattggttg
    30121 cgccaatacc cgcctgcgcc agtttttcgt ccaggtcgcg tccatcggcg actttttcca
    30181 gctgcgcggc ggcatccagc cgtgcctagc gttcagcctg acgcgtttgt aaacgtttaa
    30241 gcggctccgc cgccgtagac acattcgacg cggctccgac ggtcgaagtc gtcaccgcct
    30301 gctgcgcgcg ctgcatggct tctgtcgcct taaccacttc aagttgctgc tcaaactgcg
    30361 caatccgctg gcctgtcgcc gttacggcct tctccaccgc atcacgagag gcttccagat
    30421 tagtcagcac ctgttcttcg gcaagaatgg cattttccag acgggctatt tcttccgcca
    30481 cttcgttgag taaagcggcg tcgacattct tactcattgc cgccaacgcc cgcgtttcaa
    30541 ggctgacttt acgcgcacgt aaatcattca gcttgtcatg gcttagcttc acccgcgcca
    30601 ataaatccac tctggattta cccgctttat ccagctcggc ttttgcgtcg cgaatatgct
    30661 gctccagcat acgtacaccc tgtgcttcat caatggcttc ttctgcctga gcaacgaatg
    30721 atttacctaa cgtgaacaaa ctttttaaaa ttcccatgta agccgcctgt attattcctg
    30781 tgaatagact tgtgttattt cagcgatatc caacgcattt tctacaagcg tggtgatttc
    30841 cagcgtcacg tcggcaagcg acgaatttaa cgacaacgcg ccaaaagcga cataatattc
    30901 ctcctgtttt accagggcaa taccgaccga agacagcggt aaaaccttct gatttctcag
    30961 caagaaaaga ttaaattccg cggtatctct aatcgtattt accggacaga tataagtctc
    31021 gataactatt tgttgcgagg taaataaaac cgtcagtggt aaatcgccat aatcattcat
    31081 ttttattatt aatgaagatt cattattttc tatatcaata tctaattcgg cgatgttgtt
    31141 taacgcatcc gccagcgtcc gtggagtcca tgccatatta ttatctctat ctctttttta
    31201 taaataaagg gagttacagg gtaggttttg ctttttatat taccagccaa agat
//
LOCUS       DAJVKX010000044        29755 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000044 DAJVKX010000000
VERSION     DAJVKX010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29755
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.044"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(338..532)
                     /locus_tag="OPY25_002040"
                     /pseudo
     CDS             complement(338..532)
                     /locus_tag="OPY25_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460211.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
     gene            958..3570
                     /gene="pepN"
                     /locus_tag="OPY25_002041"
     CDS             958..3570
                     /gene="pepN"
                     /locus_tag="OPY25_002041"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HCS0927658.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIELTFDLDAEKTVVTAISQAVR
                     HGAPDAPLRLDGEDLTLVSIHVNDAPWTAYKEEEGALIISDLPERFTLRIVNEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITWYLDRPDVLARFTTKIIADKSKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDETRFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRISNVRTMRGLQFAEDASPMAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV
                     KDDYNPETEQYTLTISQRTPATADQAEKQPLHIPFAIELYDNEGNVIPLQKGGHPVNA
                     VLNVTQAEQTFTFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSANE
                     IAELFEVIDPIAIAQVREALTRTLAAELADEFLAIYNANHLDEYRVDHGDIGKRTLRN
                     ACLRFLTFGETELANTLVSKQYRDANNMTDALAALSAAVAAQLPCRDTLMQEYDDKWH
                     QDGLVMDKWFILQSTSPAENVLETVRSLLKHRSFSMSNPNRIRSLIGAFAGSNPAAFH
                     AQDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDDKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            3778..4788
                     /gene="pyrD"
                     /locus_tag="OPY25_002042"
     CDS             3778..4788
                     /gene="pyrD"
                     /locus_tag="OPY25_002042"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HCS0927659.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPLEALVRQKVPT
                     KPVTCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSLEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICME
                     KVYAYAGYIAINISSPNTPGLRTLQYGDALDDLLTAIKNKQNDLQVIHHKYVPVAVKI
                     APDLCEEELIQVADSLLRHNIDGVIATNTTLDRSLVQGMKNCQQTGGLSGRPLQLKST
                     EIIRRLSLELKGQLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            4954..5496
                     /gene="zapC"
                     /locus_tag="OPY25_002043"
     CDS             4954..5496
                     /gene="zapC"
                     /locus_tag="OPY25_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HCS0927660.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFSRKMLTPDAF
                     CPTGFCVDDAALYFSFEEKCRDFELTKEQRAELVLNALVAIRYLKPQMPKSWHFVAHG
                     EMWTPGTGDAASVWLSDTAEQVNLLVVEPGENAALCLLAQPGVVIAGRTMQLGDAIKI
                     MNDRLKPQVHCHSFSLEQAV"
     gene            complement(5493..6602)
                     /locus_tag="OPY25_002044"
     CDS             complement(5493..6602)
                     /locus_tag="OPY25_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbX family protein"
                     /protein_id="HCS0927661.1"
                     /translation="MATLSRLFIHPVKSMRGIGLTHALADISGLAFDRIFMVTESDGT
                     FITARQFPQMVRFTPSPLHDGLHLTAPDGSSALVRFTDFTPQDAPTEVWGNHFTARVA
                     PTAINQWLSGFFSRDVQLCWVGPQLTRRVKRHNAVPLGFADGYPYLLTNEASLRDLQQ
                     RCPAGVQMEQFRPNLVVSGVAAWEEDSWKVLRIGDVIFDVVKPCSRCIFTTVSPEKGQ
                     KHPSGEPLATLQAFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKAYGATT
                     LDDSVTPEKHPDGSVTIDWQGQTFCGNNQQVLLEQLENQGIRIPYSCRAGICGCCRIR
                     LLEGEVSPLKKSAMGDDGTILSCSCVPKTALRLEN"
     gene            6701..8809
                     /gene="rlmKL"
                     /locus_tag="OPY25_002045"
     CDS             6701..8809
                     /gene="rlmKL"
                     /locus_tag="OPY25_002045"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HCS0927662.1"
                     /translation="MNSLFASTARGLEELLKIELEKLGAVGCQVVQGGVHFQGDTRLI
                     YQSLMWSRLASRIILPMGECKVYSDLDLYFGVQAINWTEIFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLH
                     LRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGL
                     HRGHWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIERARSNAR
                     RAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSDPALIALHSLLGRTMK
                     NQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVA
                     EDYANRLRKNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTV
                     DAQKARQRLFDIIAATLSVLGIPPNKLVLKTRERQKGKNQYQKMSEKGEFLEVSEYNA
                     RLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGGARNTTT
                     VDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKR
                     MEESFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKT
                     LSPDFARNRQIHNCWLIRAA"
     gene            8822..10729
                     /locus_tag="OPY25_002046"
     CDS             8822..10729
                     /locus_tag="OPY25_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0927663.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNIAGSVYDFVAEGIEEQAEYLKRYH
                     EISRLVMTDPSEKNLNEMARVQEQLDHHNLWQLENRINEVLAQLGLDPNAALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERSERREVMGTAKMQVEEATRSGKIVFEMENVDYQVEGKQL
                     VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPEKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDGYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYIGGYHDARAQQEQHLATKQPMTKKNEEVIAPKAEIVKRGSSKLSYKL
                     QRELEQLPGQLEDLEAKLEALQAQVADAAFFSQPHEQTQKVLADLSQAEQELEQAFER
                     WEYLEGLKNGA"
     gene            10744..11997
                     /gene="pqiA"
                     /locus_tag="OPY25_002047"
     CDS             10744..11997
                     /gene="pqiA"
                     /locus_tag="OPY25_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HCS0927664.1"
                     /translation="MCEHHHAAKHILCPQCDMLVALPRLSHGQKAACPRCGATLTTEW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEVTLLEIPGVMFSEDYASLGTF
                     FLLFVQLVPAFCLVTILLLVNRASLPLSVKKTLARIFFLLKSWGMAEIFLAGVLVSFV
                     KLMAYGDIGIGSSFIPWCLFCLVQLRAFQCVDRRWLWDDIAPQPALAQPLTPGITGIR
                     QSLRSCACCTAILPAESLVCPRCHTKGYVRRKNSLQWTLALLFTSIMLYLPANILPIM
                     ITDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHFIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMNIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDREYEPGHEES"
     gene            12002..13642
                     /gene="pqiB"
                     /locus_tag="OPY25_002048"
     CDS             12002..13642
                     /gene="pqiB"
                     /locus_tag="OPY25_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HCS0927665.1"
                     /translation="MEPKKGEAKVQKVKNWSPVWIFPIVTALIGAWILFYHYSHQGPE
                     VTLITTNAEGIEGGKTTIKSRSVDVGVVESATLTDDLTHVQIKARLHSGMEKLLHKDS
                     VFWVVKPQVGREGISGLGTLLSGAYIELQPGSKGSQPESYQLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGAVETSSFDPQKRTMSYQLFIKAPNDRLVTSNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLFGGGVSFDVPEGLEQGQPVAEKTAFNLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPLEFRGIRLGTVSKVPFFASNMRQVFNDDYR
                     IPVLVRIEPERLKAQLGENADVGAHLTELLKRGLRASLKTGNLVTGALYVDLDFYPKE
                     PPITGLREFDGYEIIPTVSSGLAQIQQRLVETLDKINNLPLNPMIEQATNTLSESQRT
                     MRRLQTTLDNMNKITSSQSMQQLPADMQTTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            13639..14202
                     /gene="pqiC"
                     /locus_tag="OPY25_002049"
     CDS             13639..14202
                     /gene="pqiC"
                     /locus_tag="OPY25_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HCS0927666.1"
                     /translation="MKKWLVVIMAFWLASCSSGGENKSYYQLPIAQSGVQSTASQGNR
                     LLWVEQVSVPDYLAGNGVVYQTSDVQYVIANNNLWASPLDQQLRNTLVANLSARLPGW
                     VVASQPLGTTQDTLNVTVTGFHGRYDGKVIVSGEWLLNHNGQLIKRPFHIEASQQKDG
                     YDEMVKVLASAWSQEAAAIADEIKRLP"
     gene            14456..14623
                     /gene="rmf"
                     /locus_tag="OPY25_002050"
     CDS             14456..14623
                     /gene="rmf"
                     /locus_tag="OPY25_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HCS0927667.1"
                     /translation="MRRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSYWLGGW
                     RQAMEDRAVMA"
     gene            complement(14723..15241)
                     /gene="fabA"
                     /locus_tag="OPY25_002051"
     CDS             complement(14723..15241)
                     /gene="fabA"
                     /locus_tag="OPY25_002051"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HCS0927668.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHD
                     LKVGLFQDTSAF"
     gene            complement(15310..17070)
                     /locus_tag="OPY25_002052"
     CDS             complement(15310..17070)
                     /locus_tag="OPY25_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HCS0927669.1"
                     /translation="MTITKLAWRDLVPDSESYQEIFAQPHATDENDTLLSDTQPRLQF
                     ALEQLIQPWASSSFMLTKAPEEQEYLTLLSDAVRALQTDAGQLTGGHYDVSGHTVHYR
                     AAQNAQDNFATVTQVVSADWVEAEQLFGCLRQYNGDITLQPGLVHQANGGVLIISLRT
                     LLAQPLLWMRLKAIVSRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELAEQAIYSEFEDNLQIADAEAMTLWCQWVTRIALRDNLPPPAPDAWPVLIREAV
                     RYTGEQDTLPLCPLWIARQFKEASPLCEGDTCGAEALSLMLARREWREGFLAERMQGE
                     ILQEQILIETEGERVGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFNDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LANVPVNQNIAITGSVDQFGRAQPVGGLNEKIEGFFAICEQRELNGKQGVIIPAANVR
                     HLSLKSELLQAVKEEKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQATQ
                     QEGRHRFPWPLRWLNAFIPN"
     gene            17256..17708
                     /gene="matP"
                     /locus_tag="OPY25_002053"
     CDS             17256..17708
                     /gene="matP"
                     /locus_tag="OPY25_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HCS0927670.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLL
                     LALENEPVRVNVWIDRHMNPALLNRMRQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAEHKEKYATQMTTLKQDLQALLGKK"
     gene            complement(17780..18832)
                     /gene="ompA"
                     /locus_tag="OPY25_002054"
     CDS             complement(17780..18832)
                     /gene="ompA"
                     /locus_tag="OPY25_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HCS0927671.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYAGAKLGWSQYHDTGF
                     IHNDGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNTNGAYKAQGVQLTA
                     KLGYPITDDLDVYTRLGGMVWRADTKSNVPGGASTKDHDTGVSPVFAGGIEYAITPEI
                     ATRLEYQWTNNIGDANTIGTRPDNGLLSVGVSYRFGQQEAAPVVAPAPAPAPEVQTKH
                     FTLKSDVLFNFNKSTLKPEGQQALDQLYSQLSNLDPKDGSVVVLGFTDRIGSDAYNQG
                     LSEKRAQSVVDYLISKGIPSDKISARGMGESNPVTGNTCDNVKPRAALIDCLAPDRRV
                     EIEVKGVKDVVTQPQA"
     gene            complement(19187..19696)
                     /gene="sulA"
                     /locus_tag="OPY25_002055"
     CDS             complement(19187..19696)
                     /gene="sulA"
                     /locus_tag="OPY25_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HCS0927672.1"
                     /translation="MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPM
                     MAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLES
                     MIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSG
                     LKIHSNLYH"
     gene            19913..20518
                     /locus_tag="OPY25_002056"
     CDS             19913..20518
                     /locus_tag="OPY25_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family DNA transformation protein"
                     /protein_id="HCS0927673.1"
                     /translation="MRALSYDRIYESQEYLASLGTIQYRSLFGSYSLTVEDTVFAMVA
                     NGELYLRACEESVPYCVKHPPAWLMFMKCGRPVMLNYYRVDESLWRDQQQLVRLSKYS
                     LDAAMKEKHSRILQHRLKDLPNMTFHLETLLNESGIKDENMLRILGAKMCWLRLRQSN
                     PLLTVKVLYALEGAIVGVHEAALPASRRQELADWAHSLTAG"
     gene            complement(20505..22658)
                     /gene="yccS"
                     /locus_tag="OPY25_002057"
     CDS             complement(20505..22658)
                     /gene="yccS"
                     /locus_tag="OPY25_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HCS0927674.1"
                     /translation="MLSPLIRRYTWNSTWLYYIRIFIALCGTTALPWWLGDVKLTIPL
                     TLGMVAAALTDLDDRLAGRLRNLIITLICFFIASASVELLFPWPWLFALGLTLSTSGF
                     ILLGGLGQRYATIAFGALLIAIYTMLGASLYDHWYQQPLLLLAGAVWYNLLTLTGHLL
                     FPIRPLQDNLARSYEQLAHYLELKSRLFDPDIEDESQAPLYDLALANGQLMATLNQTK
                     VSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLRDYFRHSDVMFRFQR
                     LMSMQAQACTQLARCILLRTPYQHDPRFERVFTHIDAALERMRASGASLELLNTLGFL
                     LTNLRAIDAQLATIESEQAQAMPRNESENQLADDSLHGFSDIWLRLSRNFTPESALFR
                     HAVRMSLVLCIGYALIQITGMRHGYWILLTSLFVCQPNYNATRHRLALRIIGTLVGVA
                     IGLPILWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEGFEV
                     ALPRVIDTLIGCAIAWAAVSFIWPDWRFRNLPRVLQRATDANCRYLDAILEQYHQGRD
                     NRLAYRIARRDAHNRDAELASVVSNMSSEPDVTAETREAAFRLLCLNHTFTSYISALG
                     AHREKLSNPDVLGLLDDAVCYVDDALHHQPEDEQRVHQALEGLKQRVQSLETRPDSKE
                     PLVVQQIGLLIALLPEIGRLQRQISPPTSTLITQP"
     gene            complement(22677..23123)
                     /locus_tag="OPY25_002058"
     CDS             complement(22677..23123)
                     /locus_tag="OPY25_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCS0927675.1"
                     /translation="MRTVLNILNFVLGGFATTLAWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLFPYGNEAIHVDELNPAAKSVLMNTGGTLLNIFWLLFFGWWLCLMHIASGIAQC
                     VTIIGIPVGIANFKIAAIALWPVGRRVVSVETARAAREANARRRFE"
     gene            23247..25301
                     /gene="helD"
                     /locus_tag="OPY25_002059"
     CDS             23247..25301
                     /gene="helD"
                     /locus_tag="OPY25_002059"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HCS0927676.1"
                     /translation="MELKATSLGKRLAQHPYDRAVILNAGVKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPEDKVVRLHGTEWSETQQFHRYLDAHWRRWSQEMSDVAAQA
                     LQEQWARISERTGGNQWLTREHVRGLEHEIRQTFAALPLPVSRLEEFAHCREIWRKCL
                     AWLQDSEGSRQQHNQAYADAMLEAHADFFTQIESSPLNPSQARAVVNGESSLLVLAGA
                     GSGKTSVLVARAGWLLARGQADAGQILLLAFGRKAAEEMDERIRERLHTEEITARTFH
                     SLALYIIQQGSKKAPVVSKLESDATARHQLFLHTWRQQCSEKKAQAKGWRQWLEEEMQ
                     WVVPEGNFWDDETLQRRLAPRLDRWVSLMRMHGGAQAEMIAGAPEECRELFGKRIKLM
                     APLLKAWKSALKAENAVDFSGLIHQAMVILEKGRFISPWKHILVDEFQDISPQRAALL
                     EALRKQNSQTTLFAVGDDWQAIYRFSGAQLSLTTAFHQTFGEGEHCHLDTTYRFNSRI
                     GDIANRFVQQNPHQLKKPLNSLTPGDKKAVTLLDESQLDALLDKLSGYAKEDERILVL
                     ARYHHLKPASLQKAATRWPKLQIDFMTIHASKGQQADYVILVGLQEGNDGFPAPARES
                     IMESALFPQVEDFPDAEERRLLYVALTRARARVWLLFNKDNPSRFVEALKQLDVPVAR
                     KP"
     gene            complement(25337..25795)
                     /gene="mgsA"
                     /locus_tag="OPY25_002060"
     CDS             complement(25337..25795)
                     /gene="mgsA"
                     /locus_tag="OPY25_002060"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCS0927677.1"
                     /translation="MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYA
                     TGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK"
     gene            complement(25890..26552)
                     /locus_tag="OPY25_002061"
     CDS             complement(25890..26552)
                     /locus_tag="OPY25_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HCS0927678.1"
                     /translation="MKTGALATFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLL
                     RGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLISQVNFQLPRLE
                     NEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASL
                     PQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQP
                     PS"
     gene            26726..27139
                     /locus_tag="OPY25_002062"
     CDS             26726..27139
                     /locus_tag="OPY25_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCS0927679.1"
                     /translation="MKETDIADVLTSTRTIALVGASDKPDRPSYRVMKYLLEQGYHVI
                     PVAPKVAGKTLLGQQGYATLADIPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWLQL
                     GVINEQAAVLARDAGMTVVMDRCPAIEIPRLGLAK"
     gene            complement(27184..27501)
                     /gene="hspQ"
                     /locus_tag="OPY25_002063"
     CDS             complement(27184..27501)
                     /gene="hspQ"
                     /locus_tag="OPY25_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HCS0927680.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPEYSLDEPSPDELAVND
                     ELRAAPWYHVVMEDDDGQPVHTYLAEAQLRSEMRDEHPEQPSMDELARTIRKQLQAPR
                     LRN"
     gene            complement(27559..28770)
                     /gene="rlmI"
                     /locus_tag="OPY25_002064"
     CDS             complement(27559..28770)
                     /gene="rlmI"
                     /locus_tag="OPY25_002064"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HCS0927681.1"
                     /translation="MTESTFPQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLG
                     ETIDIVDHQGKWLARGAWSPASQIRARVWTFDKTESIDIAFFTRRLRQAQQWRDWLAK
                     KDGLDSYRLIAGESDGLPGVTIDRFGHFLVLQLLSAGAEYQRAALISALQTCYPDCAI
                     YDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEHGMKLLVDIQGGHKTGYYLDQRDS
                     RLVTRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLD
                     LSKAEFVRDDVFKLLRAYREHGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQ
                     LLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEG
                     LYLKGFACRVM"
     gene            28985..29532
                     /locus_tag="OPY25_002065"
                     /pseudo
     CDS             28985..29532
                     /locus_tag="OPY25_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460055.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
     gene            29558..>29755
                     /locus_tag="OPY25_002066"
     CDS             29558..>29755
                     /locus_tag="OPY25_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCS0927682.1"
                     /translation="MHIRHQDLTTAEVRSSHLHRLHRVTLFSAAICHITQGSKVIIQD
                     DSRLVAGPGELIIIPANTPLEI"
BASE COUNT         7291 a         7344 c         8142 g         6978 t
ORIGIN      
        1 atatatcaaa agcaatatgc ctttgtacag attaagactt attccattaa aaatttacgg
       61 ttttagacga ttatcttact catggtacgc aggactccgc cctctcaacc aattacagat
      121 gactggccag gctggcttcg ttgcatcagc ctggtctacc agaccccgat actttacttc
      181 ccgtctccga tgttctctaa tacgggcact gtgctcgcat atacgcgatg gcattctgaa
      241 cagtgtattg ccatcattga ttcatcactg aattcctaat tctatgtcgt cggtatttgg
      301 agtgatctga tcctacccgc gtaatctgaa accagccaag ccacctgttt aacttttcgc
      361 gatcgctttt gttggtatca ctattcaagc agtttgcctg catcggcttc accctcactt
      421 cggcatcagg gaaaatctgg tgcatccgct tcgtcagttc ggccagaatg atctcgctgg
      481 ccccttcgag tccttcaaca ttacgcttgt cataaaccag ttctacgaac atacgtgctt
      541 cgccagccac tgtttttata tacagtattt tgctttggcg gttttgtctg tcaaggcatg
      601 aaccacttgt ttttaaattt tggggaacat actgcgggcg tgtttgttat cgatttgccc
      661 tgcagggctg atggggtctg gcgttgacta aaattatgtg tggggcatgg atggggcaaa
      721 agtggtctgt gaagttcgtt aaagttcgtt aataaagctt tatctcgatc tcgctcatcc
      781 cttgtttaaa gcgctcctgg acgatcttta tcgattttaa aaactatgag tacatattat
      841 aaaaatgtag caaataggcc gtttgtgcct gaaaagatga acattctgcg tagcgcgatt
      901 tgcgcaacag gaatagactg gagtcgacac tctacacaaa gatgcgaaag gttttttatg
      961 acacaacagc cacaagccaa ataccgccat gactatcgcg cgccggatta ccagattact
     1021 gatattgaat tgacctttga cctcgatgcc gaaaaaaccg tggtcaccgc aataagccag
     1081 gctgttcgtc atggcgcgcc tgatgcgcct cttcgccttg atggggaaga tttaacgctg
     1141 gtatctatcc acgtcaacga tgcgccgtgg acagcatata aggaagaaga gggcgcgctt
     1201 atcatcagcg acctgccaga gcgttttacg ttacgcattg tcaacgagat aagtccggcg
     1261 gcgaatacgg cgctggaagg attgtaccag tccggcgatg cgctctgtac ccagtgtgaa
     1321 gcggagggct tccgccatat tacctggtat cttgaccgcc cggacgtact ggcgcgattt
     1381 accaccaaaa ttattgccga taaaagcaaa tatccgttcc tgctttccaa tggcaaccgt
     1441 gttgcgcagg gtgaactgga gaatggccgt cactgggttc agtggcaaga tccgttcccg
     1501 aaaccgtgtt atctgtttgc gctggtggcc ggtgattttg acgtgctgcg cgataccttt
     1561 accacccgct ccgggcgtga agtcgcatta gaactgtacg ttgaccgtgg caatctggat
     1621 cgcgcgccgt gggcaatgac ctcgctgaaa aattccatga aatgggatga aacgcgtttt
     1681 gggctcgaat atgacctcga catctatatg attgtcgcgg tggatttctt taatatgggc
     1741 gcgatggaga ataaaggtct caatatcttt aactccaaat acgtgctggc gcgaaccgat
     1801 accgcgacgg ataaagatta tctcgatatt gagcgcgtga taggccatga gtatttccac
     1861 aactggaccg gcaaccgcgt cacctgccgc gactggttcc agttgagcct gaaagagggg
     1921 ctcaccgtgt tccgcgatca ggagtttagc tctgatttgg ggtcacgcgc ggtgaaccgc
     1981 atcagtaacg tgcgtaccat gcgcggttta caattcgcgg aagacgccag cccgatggcg
     2041 catcctatcc gcccggataa agtaatcgaa atgaataact tctacaccct caccgtttat
     2101 gaaaagggtg cggaagtcat tcgcatgatc cacacgttgc tgggtgagga aaatttccag
     2161 aaggggatgc agctttattt tgagcgccat gacggcagcg ccgcgacgtg tgatgacttc
     2221 gtacaggcga tggaagatgc ttctaatgtc gatttgtccc atttccgccg ctggtacagt
     2281 cagtccggca cgccgattgt aacggtaaaa gatgattata atccggaaac cgagcagtac
     2341 acgttgacca tcagccagcg cactccggcg acggcggatc aggcggagaa gcagccgctg
     2401 catattccat tcgccatcga actgtacgat aacgaaggca acgtcattcc gttgcaaaaa
     2461 ggcggtcacc cggtcaatgc cgtgctgaac gtcacgcagg cggagcagac atttaccttc
     2521 gataatgtct acttccagcc tgttccggcc ttgctgtgcg agttttcagc gccggtgaag
     2581 ctggaatata aatggagcga tcagcagttg acgttcctga tgcgccatgc gcgcaatgat
     2641 ttctcccgtt gggatgcggc gcaaagcctg ctggccacat acattaaact gaatgtggcg
     2701 cgtcatcagc aggggcaacc gctatcgctt ccggtgcatg tcgctgatgc gttccgtgca
     2761 gtactgttgg atgagaaaat cgatccggcg ttggccgcag aaattttaac gctgccttcg
     2821 gccaatgaaa ttgcggagct gtttgaggtc attgacccga tcgccattgc gcaagttcgt
     2881 gaagcgctaa cgcgtacgct ggcggcagaa ctggcggatg agttcctggc tatctataac
     2941 gccaatcatc tggatgagta tcgtgttgat cacggcgata tcggtaagcg cacgctgcgc
     3001 aatgcttgcc tgcgcttcct gacgttcggc gagacggagc tggctaatac gctggtcagc
     3061 aaacagtatc gcgacgccaa taatatgacc gatgcgctgg cggccctgtc tgctgcagtg
     3121 gcggcgcagt tgccgtgccg cgatacgctg atgcaggagt atgacgataa gtggcatcag
     3181 gacggcctgg taatggataa atggtttatc ctgcaatcca caagcccggc ggaaaatgta
     3241 ctggaaaccg tacgcagcct gctcaaacac cgttctttca gtatgagcaa cccgaaccgc
     3301 atccgttcat taattggcgc gtttgctggc agcaacccgg cggcgttcca tgcgcaagac
     3361 ggtagcggat accagttcct ggtcgagatg ctgaccgatc tgaatagccg taacccgcag
     3421 gtagcatctc gcctcattga accgctgatt cgtctgaaac gttatgatga taagcgtcag
     3481 gagaaaatgc gcgcggcgct ggagcagtta aaaggactgg agaatctttc cggcgatctg
     3541 tacgagaaga taactaaagc gttagcctga cagtatccgt tataaagagg taaaacatgc
     3601 ccggtaagcg ttagcgctgc cgggtatttt tttgccggat gatgacgctt cctggcgaaa
     3661 cgtgaagtga gaatgaagga aaacgattgc tatttattgc cataggtcaa ttcccttttg
     3721 ctttgttatc gcccataata cgcccccggt ttgcacaccg ggaatccagg agagttcatg
     3781 tactatccct tcgttcgtaa agcccttttc cagctcgatc cagagcgcgc tcatgaattt
     3841 acatttcaac aattacgccg cattacaggt acgccgctgg aagcgctggt gcgccagaaa
     3901 gtaccgacaa agccggttac ctgcatggga cttaccttta aaaatccact ggggctggct
     3961 gccggtctgg ataaagacgg ggagtgcatc gacgcattag gcgcgatggg gtttggctcc
     4021 ctggaaatcg gcaccgtgac gccgcgccca cagccgggta acgataagcc acgtcttttt
     4081 cgtctggtgg atgctgaagg tctaatcaat cggatgggct ttaataatct gggcgtcgat
     4141 aacctggtcg agaatgttaa aaaagcccat tttgatggta ttctgggaat taacatcggt
     4201 aaaaataaag atacgcctgt cgaaaatggc aaagatgact acctgatttg tatggaaaaa
     4261 gtctatgctt atgcgggtta tatcgccatt aatatttctt cgccgaatac gccagggtta
     4321 cgtacgctcc agtatggcga tgcgctggac gatctgttaa ctgccattaa aaataagcaa
     4381 aacgatcttc aggtgatcca ccataaatat gtgccggtgg cagtaaagat cgcgccggat
     4441 ctttgtgaag aagaattgat ccaggttgcc gatagcctgc ttcgtcataa tattgatggg
     4501 gtgattgcga caaataccac cctcgatcgt tctctggtac aaggaatgaa aaattgccag
     4561 caaacggggg gattaagtgg ccggccatta caattaaaaa gcacagaaat tattcgccgt
     4621 ttatccctgg agttaaaagg acaattgcct attatcggcg tcggcggcat tgactcagtt
     4681 atcgccgcgc gcgagaagat agcggcagga gctacgctgg tacaaattta ttccggcttt
     4741 atttttaaag gcccgccatt gattaaagaa atcgtaacgc acatctaaac tttacccttt
     4801 atcagacaac cagggcttta tttccggcac tggttgtttt atatttctcc actgttgctt
     4861 atttagacat tttaggcttt tattattggg gtaataaacg aagcggcaaa aggacaatgc
     4921 tgttacgagt tgcttaaaag cgggagagag gtgatgcgaa ttaaacctga cgataactgg
     4981 cgctggtatt atgatgaaga gcacgatcgt atgatgctcg atctcgccaa tggtatgctt
     5041 tttcgctcgc gcttctctcg taaaatgctt acgccggacg cgttttgccc gaccggtttt
     5101 tgtgtggatg atgccgcgct ctatttttcc tttgaagaaa aatgccggga tttcgaatta
     5161 accaaagagc aacgcgcgga gctggtattg aatgcgctgg tggcgattcg ctatctcaaa
     5221 ccgcagatgc cgaaaagctg gcattttgtg gcgcatggcg aaatgtggac cccgggcacg
     5281 ggtgatgccg caagcgtctg gttaagcgat acggcggaac aggttaattt gctggtcgtt
     5341 gagccgggag aaaatgccgc gttgtgtctg ctggcacagc caggcgtggt gatagcaggc
     5401 cgaaccatgc agcttggcga tgcgattaaa attatgaacg acaggctgaa accgcaggtt
     5461 cactgtcaca gtttcagcct tgaacaagcg gtttaatttt ccagtcgtaa cgcggtctta
     5521 ggcacgcagc tacagctcag aatcgtacca tcgtcaccca tagccgattt tttcagcgga
     5581 cttacttcgc cttccagcaa acgtatccgg cagcaaccac agataccagc ccggcaagaa
     5641 tacggaatac gaattccctg attctccaac tgttccagta gcacctgttg attattcccg
     5701 cagaaggttt gcccctgcca gtcgatggtt acactcccgt ccgggtgttt ctctggcgta
     5761 acgctgtcgt cgagcgttgt ggcgccataa gcttttgccg gcgctgtcgc cagtatctcc
     5821 acctcatcgc cgacgcgaat gacgccgcta ttgcgggcaa tcagattctg accgaaatcc
     5881 acatcgccat tgtcctgggc ggtacgaaaa gcttgcagtg tcgccagcgg ttcgccggaa
     5941 ggatgttttt gccccttttc agggctgacg gtcgtaaaaa tacagcgact acagggcttc
     6001 acgacgtcaa aaatcacatc gccaatgcga agcactttcc agctatcttc ctcccaggcc
     6061 gctacgccgg aaaccactaa gtttgggcga aattgttcca tttgtacgcc tgccggacaa
     6121 cgctgttgca gatcgcgcag tgaggcttcg ttggtcaata aatacgggta gccatcggca
     6181 aatcccagcg gcaccgcgtt atgccgttta acccggcgcg tcaactgcgg cccaacccag
     6241 cacaactgga catcgcggga gaaaaagccg ctcaaccatt gattaatcgc cgtcggggcg
     6301 acgcgagcgg taaaatggtt tccccagacc tcggtcggcg catcctgcgg ggtgaaatcc
     6361 gtaaagcgaa ccagcgcgct gctgccgtct ggcgcggtca aatggaggcc gtcgtgtaag
     6421 ggagaggggg taaaacgtac catttgtgga aactggcggg cggtaataaa tgtgccgtca
     6481 gactcggtta ccatgaagat gcgatcaaaa gccaggccgc tgatatctgc cagcgcatga
     6541 gtcaggccaa tgccgcgcat ggatttgacc ggatgaataa agagccgtga taacgtcgcc
     6601 accgtacagt ccctcaaatg aaaataagcc ttcaacttta tgacatgggc gtgagattag
     6661 ctataatgcg caacaatttt cttagcgtaa aagtgacaat atgaattctc tgtttgccag
     6721 tacggcccgc gggctggaag agctgttaaa aattgaactg gaaaaactgg gcgccgtagg
     6781 gtgtcaggtt gttcagggtg gggtccattt tcagggcgac acgcggctta tttaccagag
     6841 cctgatgtgg agccgcctgg cctcgcgtat tatcctgccg atgggtgagt gcaaggtcta
     6901 cagcgatctc gatctttact tcggcgttca ggcgataaac tggacagaga tttttaatcc
     6961 tggcgcgacg tttgcggtgc atttcagcgg cctgaacgac accatccgta atagtcagta
     7021 tggcgcgatg aaagttaaag acgcgattgt cgatgcgttt acgcggaaaa atcttccgcg
     7081 tccaaatgtg gaccgcgaat cgccggacct ccgtattaac gtctggctga ataaagaaac
     7141 ggccagcatt gcgctggatc tcagtggtga tggcctgcac ctgcgcggtt atcgcgatcg
     7201 caccgggctg gcgccaatta aagagacgct ggcggcagcg attgttatgc gttccggctg
     7261 gcaaccaggt acgccgctgc tcgaccctat gtgtggttcg gggacactgt tgattgaggc
     7321 cgcgatgtgg gcgaccgatc gcgcgccggg cctgcatcgt ggtcactggg gatttagcgg
     7381 ctgggcgcag catgacgagg ctatctggca ggaagtgaaa gccgaagcgc agacccgggc
     7441 gcgtaagggg ctggcggagt attcctctca tttctacggt tccgacagcg atgcgcgcgt
     7501 cattgagcgg gcgcgcagca acgcccgtcg cgccggtatc ggggagctta tcacttttga
     7561 agtgaaagat gtggcgcaac tgagtaatcc attgccgaaa ggcccgtatg gtacggtgat
     7621 cagtaacccg ccttacggcg aacgtctgga cagcgatccg gcgctgattg cgttgcacag
     7681 cctgttgggc cgtaccatga aaaatcagtt tggcggctgg aacctgtcgc tgttcagcgc
     7741 ttcgcccgat ttgctgggca gcctgcaatt acgcgccgac aaacagttta aagccaagaa
     7801 tggcccgctg gactgtgtgc agaaaaacta tcatattgcg gaaaccacgg cggacagtaa
     7861 accggcgacg gtggcggaag attacgctaa tcgcctgcgt aaaaatctta aaaagctgga
     7921 gaaatgggcg cgccaggaag ggattgaatg ctatcgcttg tatgatgccg acctgccgga
     7981 atataacgtg gcggtagacc gttacggcga ctgggcggtg attcaggaat atgcgccgcc
     8041 gaaaacggtg gatgcgcaaa aagcgcggca acgtctgttc gatattattg cggcaacctt
     8101 gtcagtgctc ggtattccgc cgaataaact ggtgttaaaa acccgcgaac ggcaaaaagg
     8161 aaaaaaccag tatcagaaaa tgagcgagaa gggcgagttc cttgaggtca gcgaatataa
     8221 tgcgcgctta tgggtaaatc tgacggatta tctcgacacc ggtctgttcc tcgatcaccg
     8281 tattgcccgc agaatgctgg gagaaatgag caaaggcaaa gatttcctga atctcttttc
     8341 ttataccggc agcgccagcg tacatgcggg tctgggcggc gcgcgcaaca ccacaacggt
     8401 ggatatgtcc cgcacctatc tggagtgggc cgaacgtaat ttgcgtctga acggactgag
     8461 cggccgcgcg catcgcctga ttcaggccga ctgcctgggc tggctgcgcg aggcgaatga
     8521 acagttcgat ttgatcttta tcgatccgcc gacgttctct aactcaaaac gtatggaaga
     8581 gtcgtttgat gttcagcgcg atcatgtcgc gttaatgaaa gatttaaaac gcctgctgcg
     8641 taaaggcggc accatcatgt tctcaaataa taagcgcgga ttccgtatgg atctggaagg
     8701 gctggctgag ctggggctta ccgcacaaga aattacgcaa aaaacgcttt ccccggattt
     8761 tgcccgtaac cgtcagattc ataattgctg gctgatccgc gccgcctgaa aggaaaagta
     8821 aatgtcatta atcagtatgc atggcgcatg gctgtcgttc agcgacgcgc cgcttctcga
     8881 taacgcagag ttgcatatcg aagataacga acgcgtctgt ctggtggggc gtaacggcgc
     8941 cgggaaatcc accttgatga agatcctcaa ccgcgaacag ggtctggacg atgggcgtat
     9001 tatttatgaa caggatctga tcgtcgcgcg tctgcaacag gacccgcccc gtaatattgc
     9061 gggtagcgtc tatgactttg tcgccgaagg tatcgaagaa caagcggaat atctcaagcg
     9121 ctatcatgag atttcccgtc tggtgatgac cgatcccagc gagaaaaacc tcaatgaaat
     9181 ggcgcgcgta caggaacagc tcgatcatca taatctgtgg cagctggaaa accgtattaa
     9241 tgaagtgctg gcgcagcttg gactcgatcc taacgccgcg ctgtcgtcgc tctccggcgg
     9301 ctggctgcgt aaagccgcgc tgggtcgggc gctggtcagc aatccgcgcg tattgttact
     9361 ggatgaaccg actaaccatc tggatatcga aactatcgac tggctggaag ggtttctgaa
     9421 aacctttaac ggaacgatta tttttatctc tcacgatcgt tcgtttattc gcaatatggc
     9481 gacccgcatt gtcgatctcg atcgtggcaa actggtcacc tatccgggaa attacgatca
     9541 atacctgctg gagaaagaag aagcgctgcg cgtagaagag ttacaaaacg cggaatttga
     9601 tcgcaaactg gcacaggaag aagtctggat tcgccagggg atcaaggcgc gccgcacccg
     9661 taatgaaggg cgcgtgcggg cgttaaaagc gatgcgtcgt gaacgcagcg agcgccggga
     9721 agtgatgggc acggcgaaga tgcaggtcga agaggcgacg cgctccggta aaatcgtttt
     9781 tgagatggaa aacgtcgatt accaggtaga aggaaaacag ctggtaaaag atttctccgc
     9841 tcaggtacag cgcggcgaca agattgcgtt aattggcccg aacggctgcg gtaaaaccac
     9901 gctactgaaa ctgatgctgg gacagcttca ggctgacagc gggcgcatcc acgtaggaac
     9961 gaagctggaa gtcgcctact tcgatcagca tcgcgccgaa ctggacccgg aaaaaaccgt
    10021 gatggataac cttgcggaag gcaagcaaga ggtgatggta aacggtaagc cgcgccatgt
    10081 actgggctat ttgcaggact tcctgtttca ccccaaacgg gcgatgacgc ccgtccgcgc
    10141 gctttccggc ggcgaacgta accgtctgct gctggcgcga ctgttcctca agccgagcaa
    10201 tcttttaatt ctcgatgaac caacgaacga tcttgacgtc gaaacgctgg aactattaga
    10261 agaattaatt gatggctatc agggcacggt actactggtc agccatgatc ggcaatttgt
    10321 cgataatacc gtgacggaat gctggatttt cgagggcggc ggcaaaatcg gacgttatat
    10381 cggcggctac catgatgcgc gtgcgcagca agagcagcat ctggcgacga aacagccgat
    10441 gacgaaaaaa aatgaggaag ttattgcccc taaagcagaa attgtaaaac gtggcagtag
    10501 caaactaagc tataaactgc agcgcgagct ggagcagtta cccggtcagc ttgaagacct
    10561 ggaagcgaag ctggaagcgc tacaggcgca ggttgcggat gcggcctttt ttagccaacc
    10621 ccatgagcaa acgcagaaag ttctggccga tttaagtcag gcggagcaag aacttgagca
    10681 agccttcgaa cgttgggagt atcttgaagg cctgaaaaac ggggcataac gaaaggagcg
    10741 cctatgtgtg aacatcacca tgctgcgaag cacatattgt gcccgcaatg cgacatgctg
    10801 gtggctttac cccgcctctc gcatgggcaa aaagcagcat gtccacgatg cggcgcaacg
    10861 ttaacgaccg agtgggacgc gccccggcag cgtcctaccg cctatgcgtt agcggcacta
    10921 tttatgttgc tgctttctaa cctttttccc ttcgtgaata tgaatgtcgc gggcgtcacc
    10981 agcgaagtca cgcttctgga aatccccggc gtcatgtttt ctgaagatta cgccagcctc
    11041 ggcacgttct ttttattatt tgtccaactg gtgccggcat tttgcctggt gaccattcta
    11101 ttacttgtca accgcgccag tctgccgttg tcggtaaaaa aaacgctggc aaggatcttt
    11161 ttcctcctca aatcgtgggg aatggcggaa atatttctcg ccggggtgtt ggtcagtttt
    11221 gttaagctga tggcttacgg cgatatcggc atcggcagca gctttattcc ctggtgctta
    11281 ttttgtctcg ttcaactgcg ggcgttccag tgtgtcgatc gccgctggtt gtgggatgat
    11341 atcgccccgc aacctgcact ggcgcagccg ttaacgccgg ggattaccgg tatccggcag
    11401 tctttgcgtt cttgcgcctg ctgtacggcg atcctgcctg cggagagtct cgtctgtccg
    11461 cgttgccata cgaaaggcta tgtccggcgt aaaaacagtt tgcagtggac gctggcgtta
    11521 ttatttacct cgatcatgct ttatctgccc gccaatatat tgccgattat gattactgac
    11581 ttactgggct cgaaaatgcc gtcgaccatt ctggctggcg tgattttgct gtggagcgag
    11641 gggtcttatc cagtggcggc ggttatcttt cttgccagta ttatggtgcc gacgctaaaa
    11701 atgatcgcca ttgcctggct ttgttgggat gcgaaaggcc acggtaagcg cgacagtgaa
    11761 cggatgcatt ttatttatga agtagtggag tttgtggggc gctggtcaat gattgatgtc
    11821 tttgtcattg ccgtactctc tgcgctggtg cgtatgggag ggttaatgaa tatttatcct
    11881 gcgatgggtg cgttgatgtt tgctttagtc gtcataatga caatgttttc tgcgatgacc
    11941 tttgatccgc gtctgtcgtg ggatcgtgaa tacgaaccag gccatgagga gtcctgatag
    12001 catggaacct aaaaaagggg aagccaaagt acaaaaggtg aaaaattggt cgcctgtctg
    12061 gatattcccg attgttactg cgcttatcgg agcctggatt ctgttttatc actacagcca
    12121 ccagggaccg gaagttacct taattaccac caatgcggaa ggcattgaag gcggaaaaac
    12181 gacgatcaaa agtcgcagcg tggatgtcgg cgtggttgaa agcgcgacgc tgactgacga
    12241 tctgacccac gtacaaatca aagcgcggct tcattccggt atggaaaagt tgctgcataa
    12301 agactcggta ttttgggtcg taaaaccgca ggtggggcgt gaaggcataa gcgggcttgg
    12361 gacgttgtta tcaggcgcgt atattgaact acaaccagga agtaagggca gtcagccgga
    12421 aagctatcag cttcttgact caccgccgtt ggcgccgccc gatgccaaag gtattcgtgt
    12481 gattctggac agcaaaaagg ccggtcagct cagtcctggc gatcccgttc tgttccgggg
    12541 ctatcgggta ggggccgttg aaaccagctc tttcgatccg caaaaacgga caatgagtta
    12601 tcagttgttc attaaggcgc caaacgatcg attggtcacc agtaatgtcc gattctggaa
    12661 agatagcggt atcgctgtgg atctgacatc ggcgggaatg cgcgtggaaa tgggatcgtt
    12721 gacgacgtta tttggcggcg gcgtgagttt tgatgtgccg gaaggacttg agcaggggca
    12781 acccgtcgcc gaaaaaacgg cgtttaatct ctacgacgat caaaaaagta ttcaggattc
    12841 gctgtacacc gatcatatcg attacctgat gttctttaaa gattcggtgc gcggattaca
    12901 acccggcgcg ccgctggagt tccgcggtat tcgtctgggg acggtaagca aagtgccttt
    12961 ctttgcgtct aatatgcgtc aggtgtttaa cgacgattac cgtattcctg tgctggtgcg
    13021 cattgaaccg gagcgtctga aagcgcaact gggagaaaat gcggatgttg gcgcgcattt
    13081 gacggaactg cttaagcgcg gtttacgcgc ttcgcttaaa accggtaacc tggtgaccgg
    13141 ggcgctgtat gtcgatctgg acttttatcc taaggagccg ccgattaccg gactacgcga
    13201 atttgatggt tatgaaatta ttcccaccgt cagcagcggc ctggcgcaaa ttcaacagcg
    13261 actggtggaa acgttggata agatcaacaa cctgccgctg aatccgatga ttgaacaagc
    13321 gaccaatacg ctgtctgaaa gccagcgtac tatgcgtcgg ttgcaaacca cgctggataa
    13381 tatgaacaag attacctcca gtcagtcgat gcagcagctt ccggcggata tgcaaacgac
    13441 gttacgcgaa cttaaccgca gtatgcaggg cttccagcct ggatcggcgg cgtataacaa
    13501 aatggtggcg gatatgcagc gtctcgatca ggtgcttcgt gagttacaac cggtgttgaa
    13561 aactctgaac gagaagagca acgcgctggt atttgaagcg aaggataaaa aagatcctga
    13621 gcctaagagg gcgaaacaat gaaaaaatgg ctagtcgtga taatggcgtt ctggctggcg
    13681 tcatgtagtt ccggcggaga aaataaaagc tattatcagc tcccgatagc gcaaagcggt
    13741 gtgcaaagca ccgcaagtca gggcaaccgt ctcttatggg tagagcaggt ttccgtacct
    13801 gactatctgg caggtaacgg tgtggtgtat caaaccagtg atgtccagta tgtgattgcc
    13861 aataacaatc tgtgggccag cccgctggat cagcaattac gtaacacgct ggtggcgaat
    13921 cttagcgccc ggcttcctgg ctgggtcgtc gcttcccagc cgttgggaac cacccaggat
    13981 acgttgaacg ttaccgtaac cggattccat ggacgttacg atggtaaggt tatcgtcagc
    14041 ggggagtggt tattaaacca caacggacaa ctgattaagc ggcctttcca tatcgaagcc
    14101 agccagcaga aagatggcta tgatgagatg gtcaaagtac tggcaagcgc atggagtcag
    14161 gaagcggccg ctatcgcaga tgagataaag cgccttccct gagataaaaa taatgtaaat
    14221 ttaaccgctt caggtcgtgc gcctgaggcg gtttttattt ttgacgccgg aaaaatagtt
    14281 gttatggctc acattttttg tacaaatgat ttaccgtata gctcacaaat atgacattgg
    14341 tgtgaatttt gcgcattgac gggcgatcca tttagaggta ttcgtgtagt gtgattgcac
    14401 attttgtaat cactgttttc ttttccacca gatacaaata tgagggaaac gaggcatgag
    14461 gagacaaaaa cgagatcgcc tggaacgggc acatcaacgt ggatatcagg ccggcatcgc
    14521 cggacgatca aaagaaatgt gtccctatca gacgctgaat caacggtcat actggttggg
    14581 aggttggcga caagccatgg aggacagggc ggtaatggcc tgattctgtc tctttagaaa
    14641 aagaaacctc cgcagtgcgg aggtttcgcc tttatgggct ttgcaagcat gataccgata
    14701 gcgcggaata tcaattcaac acttagaacg cggaagtatc ctggaacaaa ccgactttca
    14761 aatcgtgtgc ggtatagatc agacgaccat ccaccagaac ctcaccgtcc gccaggccca
    14821 tgatcaggcg acggtttacg atacgtttaa aatgaatgcg ataggtgact ttcctggctg
    14881 tcggcagaac ctgaccggta aatttcactt cgcccacgcc cagagcgcgg cctttgcctt
    14941 cgccgcccaa ccagcccagg tagaatccca ccaattgcca catagcatcc agacccagac
    15001 aaccgggcat caccggatcg ccgataaagt ggcatccgaa gaaccataga tccggattga
    15061 tatccagctc ggcttcgaca tagcctttgt cgaaattgcc gcccgtttcg gtcatcttaa
    15121 cgacgcggtc catcatcagc atgttcggcg cagggagttg cggcccttta gcgccaaaca
    15181 gttcaccacg accagaggca agaaggtctt cttttgtata ggattcgcgt ttatctacca
    15241 tgttttatgt aaaccttatt ttattgaagc acgcaggata gctaacacgt gtacgctgaa
    15301 caagtccgat cagttcggaa taaaagcgtt cagccaacgt aatggccacg ggaaacgatg
    15361 acggccttcc tgttgcgtcg cctgcgcgat acgctcctgg atagtctgca tcaacgtcgt
    15421 ttgaccttcg ccatcccaca ccagatttaa cagtagcggt aaggcgtcgg tcacgtcgtc
    15481 taccgcccag atagtgaact tctcttcttt aaccgcttgc agcagttcag atttaagact
    15541 gagatggcgg acattggcgg cagggataat cacgccctgt ttaccgttta attcccgctg
    15601 ctcgcagatg gcgaagaaac cttcaatttt ttcgtttagc ccgcccactg gttgcgcgcg
    15661 accaaactga tcgaccgagc cggtaatcgc aatattttga ttcactggca cattggccag
    15721 cgcgctgatg agcgcacata attccgccat tgaggcgcta tcgccatcca cttcgctgta
    15781 ggactgctca aaggttaacg aggcagagaa gggaatttgt tgctccagct gcaactccga
    15841 catcaggaag gcctgcataa tcatcattcc cttagcgtgg atatttccgc caagttcggc
    15901 cttgcgctca atatcgttaa attcgccatc gccgatatgc acaacacagc taattcgcga
    15961 cggttcgcca aaggcgcgcg gatgtccggg aaactcaatg acggaaagcg cattgatttg
    16021 tccaacgcgt tcgccttcgg tttcaatcag gatctgctct tgcagaatct cgccttgcat
    16081 ccgctccgcc agaaagcctt ctcgccattc gcgtcgggca agcatcagac tgagcgcttc
    16141 tgcgccgcag gtatcgcctt cgcataaagg cgacgcctcc ttaaactggc gggctatcca
    16201 cagtgggcaa agaggcagcg tatcctgttc gccggtatag cgcacagcct cgcgtatcag
    16261 gacgggccag gcgtccggtg ccggaggggg caaattatcg cgtaaagcga tacgcgtcac
    16321 ccattgacac cacagggtca tagcttctgc gtccgctatc tgtaaattgt cttcaaattc
    16381 actgtagata gcctgttccg cgagctccgg ttccatctcc tgaaaatcag ccagtgattc
    16441 acgttcgcca accagaatca ccttcagttt gagcggcatt gatggcacgg agaccggtaa
    16501 tggacgcgac tcgtcaaagg ccacccagtc aaaacgctcg cggctaacga tggctttcag
    16561 acgcatccat agtaacggct gcgccagaag ggttcgtaag gaaataatca gcacgccgcc
    16621 gttcgcctga tgaaccagtc ccggttgcag ggtaatgtcg ccgttatact gccgcaggca
    16681 accaaagagc tgttcggctt cgacccagtc agcgctgacg acttgtgtga cggtggcaaa
    16741 gttgtcttgc gcattctgcg cggcgcggta atgaacagta tgcccggaaa cgtcataatg
    16801 tccgccggtt aattgtccgg catcggtttg cagagcgcgg acggcatctg aaagtaaagt
    16861 gagatactct tgctcttcag gcgctttagt cagcataaaa gaggatgatg cccacggctg
    16921 tataagttgc tcaagcgcaa attgcagtcg tggctgagta tcactgagta aggtgtcgtt
    16981 ttcgtcagtc gcgtgtggct gtgcaaatat ctcctgatag ctttcgctat ccggaaccag
    17041 atcacgccat gcaagtttcg taatggtcaa agttgaggtt ttttagtctg ttgtaaaagg
    17101 ggggattata gcctaacccg tcacgctgca cacgcggaaa gcgaatgcaa agtaatatga
    17161 agatgtgtaa ccattcacag gttcgagatt cttttcttca gatggctaaa aaactgatat
    17221 tctgataaca gttacacggt aacattggga tcacaatgaa atatcaacaa cttgaaaatc
    17281 ttgaaagcgg ttggaaatgg aaatatctgg tgaaaaagca ccgcgaaggg gagttgatca
    17341 cccgctacgt ggaagccagt gctgcccagg aagccgtcaa tttgttgttg gccctcgaaa
    17401 atgaaccggt gcgggtaaat gtctggatag acaggcatat gaatcctgcc ttgcttaatc
    17461 ggatgagaca aaccattcgg gcaagacgca aacgacactt caatgcggag catcagcata
    17521 cgcgcaaaaa atctatcgat ttagagttta tggtctggca gcgtctggcg ggccttgcgc
    17581 agcgacgcgg taaaacatta tccgaaacga ttgtgcaact gatagaagac gcggagcata
    17641 aagagaaata tgccacgcaa atgaccacgt taaagcagga tttacaggcg ttattaggca
    17701 agaagtaacg ctgaaaggcg ttgccaccca gaccagagca aaaaaccccg cgaagcgggg
    17761 ttttttatca gacggaaact taagcctgcg gctgagttac cacgtcttta acgcctttaa
    17821 cttcgatctc tacacgacga tccggagcca ggcaatcgat cagggcagcg cgaggtttca
    17881 cgttgtcaca ggtgttgccg gtaaccgggt tagattcgcc cataccacgt gcggagattt
    17941 tgtcagacgg aatacctttg gagatcaggt aatcaacaac agactgagca cgtttttcgg
    18001 acagaccctg gttgtaagcg tcagaaccga tacggtcagt gaagcccaga acgacaacgg
    18061 aaccgtcttt cggatccagg ttgctcagct ggctgtacag ctgatccaga gcctgctggc
    18121 cttccggctt cagggtcgat ttgttgaagt tgaacagtac gtcagacttc agagtgaagt
    18181 gcttggtctg tacttccgga gccggagccg gtgccggagc tactaccgga gcagcttctt
    18241 gctggccgaa acggtaggaa acacctacgc tcagcaggcc gttgtccgga cgggtgccga
    18301 tggtgttggc atcaccgatg ttgttagtcc actggtattc cagacgggtt gcgatttcag
    18361 gggtgatggc atactcgata ccgcccgcga ataccgggga aacgccggtg tcgtggtctt
    18421 tagtagacgc gccgccaggg acgttagact tggtgtctgc acgccatacc ataccaccca
    18481 gacgggtata aacgtccaga tcgtcagtga ttggataacc cagtttagcg gtcaactgaa
    18541 cgccctgagc tttataagcg ccattggtgt tgtcgccttt gtacggcata cggcctaacc
    18601 agtcgtagcc catttcaaag ccaacgtacg ggttaacctg gtaaccacca aaagcacctg
    18661 cgcccagttg gttttcatga gtcgggccat cattgtgaat gaagccggtg tcatggtact
    18721 gagaccagcc cagtttagca ccagcgtacc aggtgttatc tttcggagcg gcctgcgcta
    18781 cggtagcgaa accagccagt gccactgcaa tcgcgatagc tgtctttttc attttttgcg
    18841 cctcgttatc atccaaaata cgccatgaat atctccaacg agataacacg gttaaatcct
    18901 tcaccggggg atctgctcaa tagttactct accgatatct acggcttatg ctgagcaccc
    18961 ctggcgatgt aaagtctaca acgtagttgg aaacttacaa gtgtgaactc cgtcagacat
    19021 gtgaaaaaac atgacgggta tacacatcat ttaacagttt cggatgataa atcgtacagc
    19081 aaagattgcg gaaaccgctt ctggcaagcg ttctcgcaaa aaaacgttag cactcaaagg
    19141 agatacgttc gcgtaaaaaa aagtccagga taaatcctaa ttttacttaa tgatacaaat
    19201 tagagtgaat ttttagcccg gaatgctgtc tcctgggtaa agcgtgcgca cgtacagggc
    19261 gcatgataaa ccctaccgca ttacctacct tcgctgcttc aaccaggctg gcatgttctt
    19321 cttctgtcag ttcttcagtc atccaaccaa ttaccacgct gtaatttcct gtacgcaaag
    19381 cgcggatcat cgactccagc gtatgacgag gcgcaagctg gctaatttgc atcactttcg
    19441 ttaatggcaa acctgaagac tgtacccatt cacggctgag cttttgctgc ggcgtgagcc
    19501 agagctgcca gcgtgattgt tggcctaact gacggagtaa aggcaaaagc aggagttgcg
    19561 ccatcatggg ctggtcttcg tggtagacaa cttcactgac cagtcctgcc gcggcatttt
    19621 ccgtagcggt gcgcgcagcg ttgtgggtag tggtaggaaa tgacgaagaa cgatttgcat
    19681 aacctgaagt gtacataatc aatccagccc tgtgagttac tgtatattca tacagtactc
    19741 ctgtggcgat gaaagatcaa ctctattttc ggaaactgtc tcgcaatttt tattcttagt
    19801 ggcgtcaaaa ataaaaatca tcttgctcgc ggagtataag ttgcctattt tcgtcattaa
    19861 cggatccgtt actgcaaatc attcttttac tttatgattt aaaaggaatt ttatgagagc
    19921 actctcttat gacaggatct atgaatcgca agaatatttg gcctctttgg ggacgatcca
    19981 gtatcgatct ttattcggta gctatagtct gactgtggag gataccgtct ttgcgatggt
    20041 ggctaatggc gagctttatc tccgcgcctg tgaagaaagc gtaccctact gtgtgaagca
    20101 tccccccgcc tggctcatgt ttatgaaatg tggacgtccc gttatgctca actattaccg
    20161 ggtggatgaa agcctgtggc gcgatcagca gcagctggta cgtttatcga agtattctct
    20221 tgacgcggca atgaaggaaa aacacagccg tattttacag cacagactca aagatctccc
    20281 caatatgacc ttccatctgg aaacattgct caatgagtca gggataaagg acgaaaatat
    20341 gttacgcata ctgggcgcga aaatgtgctg gttaaggttg cgacaaagca atcccttgct
    20401 gacggtgaaa gttttgtatg ccctggaagg cgcaattgtc ggcgtacatg aagcggcgct
    20461 cccggcgagt cgtcgccagg agcttgccga ctgggctcat tcgcttacgg ctgggtaatt
    20521 aatgtagaag tcggcggtga aatttgccgt tgcaagcgtc caatctcggg cagtaaggca
    20581 atgagcaaac caatttgttg aacaaccaga ggttctttgc tgtccggacg tgtttccagc
    20641 gactgaactc gctgctttaa accctccagc gcctggtgta cgcgctgttc gtcttctggc
    20701 tgatgatgaa gcgcatcatc aacgtagcag accgcgtcat ccagaagccc caacacgtcc
    20761 ggattgctga gcttttcgcg gtgcgcgccg agggcggaga tatagctggt aaaagtgtga
    20821 ttgaggcaaa gcagcctgaa cgccgcctcc cgggtttcag ccgtgacgtc gggttcgctc
    20881 gacatattag aaaccacgga tgccagttct gcatcgcggt tgtgcgcgtc gcgtctggca
    20941 atgcgatagg ccaggcggtt atcccgtccc tgatgatatt gctcaaggat cgcatcaagg
    21001 tagcggcaat tagcatcggt ggcgcgctgg agtacccggg gaaggttgcg aaagcgccag
    21061 tccggccaaa taaagctgac cgcagcccag gcgatagcgc agccaattaa cgtgtcgatg
    21121 acgcgcggta acgctacctc gaagccttcg cccaggaggt taaagcagag taataccagc
    21181 agggtgatga acatcgtcgc atgggcatac tgcacattac ggaatgcgaa gaaaagcacg
    21241 ccggtaatca ccagcagaac taactgtcct tcaagcgaag ggacaaacca taaaatcggc
    21301 aggccgatcg caacgcctac caacgtaccg ataatcctga gcgcaaggcg atggcgggtc
    21361 gcgttatagt taggctgaca aacgaacagg ctggtgagca atatccagta cccgtggcgc
    21421 atcccggtaa tttggatgag agcataaccg atgcacaata ccagcgacat gcgtaccgca
    21481 tggcgaaaga gagcggactc cggggtaaaa ttacggctca gacgcagcca gatgtcgcta
    21541 aacccgtgca ggctatcgtc agccaactgg ttttctgact cattgcgcgg cattgcctgg
    21601 gcctgctccg actcgatcgt cgccagttgc gcatcaatag cgcgtaggtt ggttaataag
    21661 aatccaagcg tattcagcag ctctaaagaa gcgccgctgg cgcgcatacg ttcaagcgcg
    21721 gcgtcaatgt gggtaaagac gcgttcaaag cgcggatcat gctggtacgg cgtacgcagt
    21781 aagatacagc gcgccagctg cgtacaggcc tgcgcctgca tcgacatcag acgttgaaag
    21841 cggaacatga cgtcgctatg gcgaaaataa tcgcgcagcg tctggtattg aatatgcgaa
    21901 gaactggcgc gttcatgaat atcctgcgcc acaaaatagt aatggagagt gcggcgcgta
    21961 ccgcgttgac cgcgatcgcc gcgcaggcga gtcaacaacg acactttcgt ttggttcagc
    22021 gtcgccatta actgcccgtt cgctaacgct aaatcataga gcggcgcctg gctttcatct
    22081 tcaatatcag gatcaaacag acgtgatttc agttccagat agtgcgccaa ctgttcgtaa
    22141 ctgcgtgcca gattatcctg caacggacgg atcggaaata gcagatgccc ggttagcgtc
    22201 agtaggttat accatactgc gcctgccagc aggagcagtg gttgctgata ccagtgatcg
    22261 tataaagaag cgcccagcat cgtataaatc gcaatgagta acgcgccgaa cgcgatggtg
    22321 gcatagcgtt gccctagtcc tcccaacaga ataaatccgc tggtggataa cgttaagccc
    22381 aacgcaaata gccacggcca gggaaagagc agctccacag aagccgacgc gataaaaaag
    22441 caaattaagg taatgattaa attacgcaag cgtccggcaa ggcggtcgtc gagatcggtt
    22501 agcgccgcgg caaccatacc gagcgtgagc gggatggtca gtttgacgtc gcccagccac
    22561 cagggcaggg cggtggtgcc gcacagagcg ataaaaatgc ggatgtaata cagccaggta
    22621 ctgttccagg tataacggcg aatcaacgga cttaacataa aggctatttg tcccgatcat
    22681 tcaaaacggc ggcgcgcgtt agcttctcgc gcggcgcgag cggtttctac agagacgacg
    22741 cggcgaccga caggccaaag cgcaatcgcg gcaattttaa agttcgcaat accgacaggt
    22801 atcccgatga tagtgacaca ctgcgcgata ccggaggcaa tgtgcatcag gcatagccac
    22861 cagccgaaaa aaagtaacca gaaaatattc agcaaggtac cgccagtatt cattaatacg
    22921 ctttttgccg ccggattaag ttcgtcaacg tgaatggctt cattaccgta agggaacagg
    22981 gacagtttgg ttatctccca gcaggagcgg gtcaacggca gggtaaaaat aagcacaata
    23041 ctgaccagcg tcgccagcag ccaggccagc gtagtggcaa agccgcccag tacaaagttt
    23101 aaaatattca gaacggtacg cataaaccct cagttcattc cggttttcta ttactgcggg
    23161 caattgtaac gtttttttag actggagcac gttttctctg gcggttacac tgataagcac
    23221 atctttacgt ctggattcgc tgagtcatgg aactgaaagc aacttctctt ggaaaacgtc
    23281 tggcgcaaca cccgtatgat cgtgccgtga tcctcaatgc tggggtgaaa gtgtctggcg
    23341 acaggcatga atatcttatt ccattcaatc agttattggc gattcactgt aagcgtgggc
    23401 tggtatgggg cgagctggag tttgtcctcc cggaggataa agtcgtgcgt ttgcacggta
    23461 ccgagtggtc ggaaacccag caattccatc gctatctgga cgcgcactgg cgtcgctgga
    23521 gccaggagat gagtgatgtc gccgcgcagg cattacagga gcaatgggcg cgtattagtg
    23581 agcgaacggg cggaaaccaa tggcttaccc gtgaacacgt tcgtgggctg gaacacgaaa
    23641 ttcgccagac gtttgccgcc ttaccgctgc cggtctcacg tctggaggag tttgctcact
    23701 gtcgcgagat atggcgtaag tgtctggcat ggttacagga tagcgaggga agtcggcagc
    23761 agcataatca ggcgtatgct gatgccatgc tggaagcgca tgccgacttt tttacgcaga
    23821 tagaatcttc tccgcttaat ccttcccagg ccagggcggt ggttaacggc gaatcatcgt
    23881 tactggtact ggcgggcgcg ggaagcggta agacctcggt gctggtggcg cgcgcgggtt
    23941 ggctgttggc gcgcgggcaa gccgatgcgg ggcaaattct tttactggcg tttggtcgca
    24001 aggcggcaga agagatggat gagcgtatcc gcgagcgctt acatacggaa gagattactg
    24061 cccgtacgtt ccattcgctg gcgctgtata ttattcagca aggcagtaaa aaagcgccgg
    24121 ttgtcagtaa gctggaaagt gacgccaccg cgcggcatca gctatttctg cacacctggc
    24181 gtcagcagtg tagcgagaaa aaagcgcagg ccaaaggctg gcgtcagtgg ctggaagagg
    24241 agatgcagtg ggtagtgccg gaaggtaatt tctgggacga tgagacattg cagcggcgtc
    24301 tggcccctcg cctggatcgt tgggtcagtt tgatgcgtat gcacggcggc gcgcaggcag
    24361 aaatgatcgc tggcgcgcca gaggagtgcc gcgagctgtt tggcaaacgc attaagttga
    24421 tggcgccgct gctgaaggcc tggaaaagcg cattgaaagc ggaaaatgcc gttgatttct
    24481 ccgggctgat ccatcaggca atggtgatcc tcgaaaaagg gcgttttatt agcccgtgga
    24541 agcatattct ggtcgatgaa tttcaggata tttccccgca acgggcggcg ctgttagagg
    24601 cgctacgcaa gcagaatagc cagactacgc tgtttgccgt tggcgatgac tggcaggcga
    24661 tttaccgttt tagcggggcg cagctctcct taacgacggc gtttcatcag acgttcggcg
    24721 agggcgagca ttgtcacctg gacaccacgt accgttttaa cagtcggatt ggcgatattg
    24781 ccaatcgctt tgtacagcag aatccgcacc aacttaaaaa accgttaaat agtctgaccc
    24841 caggcgataa aaaagcggtt acgttattgg atgaaagcca gttggacgcg ttactggata
    24901 aattatccgg ctatgcgaag gaggatgaac gtatcctggt gctggcgcgc tatcaccatc
    24961 tgaaacccgc gagtctacaa aaagcggcga ctcgctggcc gaagttacag atagatttca
    25021 tgactatcca tgccagcaaa ggccaacagg ccgattacgt gattcttgtc ggattgcagg
    25081 agggtaacga cggtttcccc gccccggcgc gagaatccat tatggaaagt gcgctttttc
    25141 ctcaggttga ggattttccg gacgctgaag agcggcgttt gttatatgtg gcgttgacgc
    25201 gcgcgcgtgc gcgggtctgg ctgcttttca ataaagataa tccctcgcgc tttgtggagg
    25261 cgcttaaaca gctggatgtg ccggtggcga ggaagcccta aagcgcgggc ggtatagcat
    25321 cccgcccgcg tagcggttat ttcaggcgct cggccagata acgcgcataa tccggaataa
    25381 gaatatctac agcgtcatta aaatgcgggg actggatgat aaagtccgcc gttgagacat
    25441 tagtggcgac agggatattc catacagtgg ccagacgcag tagcgctttg acatcggggt
    25501 cgtgcggtac cgcgttaagc gggtcccaga agaaaatcaa cacgtcgatt ttcccttctg
    25561 aaatgagcgc gccaacctgc tggtcgccgc ccatcgggcc gctcagcatc gcattaacgt
    25621 ccataccggt tgcgcgctgg atcagattcc ccgtggtgcc ggttgcataa agaacgtgtt
    25681 tttccagcaa cggctgatgg cgttccaccc agttcattaa catctgtttg cagtggtcgt
    25741 gagcaaccaa cgcgatatgt ttgcgcgtcg gcaaggtgcg agtcgtcagt tccataattc
    25801 gattccgtag ttaacctgtc tacagattac tggaagcgct tgatgctgca agagaaagac
    25861 aaaaaaattg cgcgctggga caactcatat caagagggcg gctgtttttc cgcccattgc
    25921 agaaaatgat ggcgtgtctg cgggtcggcc agtcggaacc aatatttcag ccgctgttct
    25981 gtcagagttt gtgattgcgg cggtacggta tcaagctctg agacgtcgga aagtaatgtg
    26041 ctgtcgtctg ccatcatcgt ggcgaactga ggaagcgagg cgcgtttcgc cgatttatta
    26101 taacgctcgg tctctatttc gtaatcgacc actttagccg tagaagtaat ggccagaata
    26161 tcgagtttta ccggaatggg catggcgtcg ccgtccaaaa gcgccagacg cggcgccgcg
    26221 ttaaaatgcg aggcttcgcg ctcgttttcc agccgcggga gctgaaaatt gacctgactt
    26281 atcagctggg tatcgaagct tatcaccagc ggcggagaaa tataaagccg ctcttcatta
    26341 ccgggcaggc ggatggtttt ttccacccgg aaaacgagtt gatgcggccc gttttccagt
    26401 tcgatgctct ctgcgccgcg taataaagag ctggacacct ttttgccgtc cagcaccagc
    26461 agatcaacct cattagacaa acggagcgtt gtggcaaaaa cagtcaccgg caaacagaga
    26521 gcaaggaagg tggctagcgc gccggttttc ataaggttct cctgtccaaa ggccgtctgg
    26581 ctaataatgt atcgaaattt ttcttagatc atgtttacta acatatagac atattttggc
    26641 gttttgctct catacatcgg tatgggatga atggttgcta tgtcaggttt gtcgtacact
    26701 ttgcaaaaca gccaggagaa agatgatgaa agagaccgat attgctgatg ttttgacgtc
    26761 cactcgcact atcgcgctgg taggtgcgag cgataaaccc gatcgtccaa gctatcgggt
    26821 aatgaaatac ctgcttgaac agggctacca tgtgattccg gttgcgccaa aagtcgcggg
    26881 taagacattg ctggggcaac aggggtatgc cacgctggcg gatattcccg aaaaagtcga
    26941 tatggtggat gtttttcgca actctgaagc tgcatggggc gtcgcgcagg aagctatcgc
    27001 catcggcgca aaaacgctgt ggctacagct tggcgtgatc aacgaacagg cggcggtact
    27061 ggcgcgggat gcaggcatga ctgtggtgat ggatcgctgc ccggcgattg agatccctcg
    27121 cctggggctg gcgaaataaa agtttaaatg gccggatatc gctctccggc cttttacata
    27181 caatcagtta cgtagtcgcg gcgcctgaag ctgcttgcga atggtacgcg ccagttcatc
    27241 catcgatggc tgttctggat gctcgtcccg catttcgctt cgcaactggg cctcggccag
    27301 ataagtatgc actggctgac catcatcatc ttccattacc acgtggtacc acggagcggc
    27361 gcgaagttcg tcgttaaccg ccagttcatc aggcgacggc tcatcaagcg aatattccgg
    27421 gtcgatatcg acgaccactc cgaggtaacc taacagggaa tggcggacct gttggccgat
    27481 accgaatttg ctggctatca tagtcacctc ccgggaaata gatacccttt atatgaggat
    27541 actattccac ttttcaagtt acatgacgcg acaggcaaac cctttcagat acagcccttc
    27601 cgggtaggtg gcgatcaccg ggtgatcggc ggcctgacgg aactgctcta taaattgtac
    27661 atcacgaccg gcatctattg cggcatcggc aatgattttc tgaaataaat cgctggtcat
    27721 cagtccggag caagagaatg tcagcagtat gccgcccgga ttgagcagtt gaatcgctaa
    27781 catgttaatg tctttatagc cccggcaggc gcccattaac tggcttttat tttcgacgaa
    27841 tttgggcggg tccatgatga tgacgtcgaa tttttcgccg tgttcacggt aagcgcgcag
    27901 caacttaaac acgtcgtcgc gcacgaattc ggctttgctc aagtccagtt ggttcagttc
    27961 aacgttttgc ctggcgatat ccagcgcatc ctgtgaggta tccacgctga caacctggcg
    28021 acaaccaccc attaacgccg acacggcaaa accgccggta taagagaagc agttcagtac
    28081 ccgctgattt tctacgtagc ggcgcgtcac cagacgactg tcgcgctgat caagataata
    28141 accggttttg tggccgccct gtatatcgac cagcaatttc ataccgtgtt cttcaattgg
    28201 caaaagcgca ggcggcagtt cgccagtgac cgggccttgc gtcagcgcca tcccttcttt
    28261 tttccgcacg gcgacgtcgc tgcgatcgta aatagcgcaa tccggatagc atgtttgcag
    28321 agcgctaatt aatgcggcgc gttgatattc ggccccggcg ctgagcagtt gcagcaccaa
    28381 aaaatgacca aaacgatcga tagtgacgcc aggcaggcca tcggattcac cggcgatcag
    28441 acgatagcta tccagaccgt cttttttcgc cagccagtcg cgccactgct gcgcctggcg
    28501 caggcggcgg gtgaaaaacg caatatcaat ggattctgtt ttatcaaatg tccagacgcg
    28561 cgcgcggatc tgggaggctg gcgaccaggc gccgcgtgct aaccactttc cctgatggtc
    28621 gacgatatcg atagtttcac cgaggttggc tttgccttcc agacgggata cggcgccgga
    28681 aaagacccat gggtggcggc ggagtaaaga tttttctcgc cctttgctga ggactaaacg
    28741 gggatattgc ggaaatgtag attcagtcat gcggagtaac ctctcacaaa cagtgacgcg
    28801 agccggatga tagttccagc cagggaccgt gaaaacgaaa tggcgcgtag ggtagcacag
    28861 atgagagggg caatcaccag cgtatggcgg tgagcgtttc tgcacaaaat agaatcgtaa
    28921 aggcacagtt tcttcagcgg acgcttttta tagtgttatt tctttacatg aagaaggaaa
    28981 tacaatgaaa acagtcttct ctttgaccgc agccgcaatg atggcattga gtggcggcgt
    29041 atctgccgcg tcggcgttta gcctcagtag cgcggatatt ccggcagatt ttcgtttaac
    29101 gcaacagcac gtctttaaag gatttggttg tagcggagaa aatatttcgc cgcagctgag
    29161 ctggcgcaat ccgcctgccg gaaccaaaag ctacgctatt accgtcttcg atcctgatgc
    29221 tcccaccgga agcggctggt ggcactggac gatggtgaat attcctgcgc agattcacga
    29281 cctgccgacg ggggctgata aaaaacgtta cccgctggag tggtgcaggg acggaatgat
    29341 ttcggttatg ctggctttgg cggcgcctgt ccgccgccgg gcgatgagcc tcatcgctat
    29401 cagtttactg tgtgggcgct gaatacggca acactgccgc tcgacagtga gtcgagtggc
    29461 gcgttggtag ggtttatgct taacgcgcat gtgattgcga aagcacaatt cacggccaca
    29521 tacggaaggt aaaacagagg acggcacggt gcaggagatg catattcgac atcaggatct
    29581 tacgacggca gaggtgcgtt ccagtcatct gcaccgtttg catcgtgtta cgcttttttc
    29641 cgccgcgatc tgccatatta cgcagggcag taaagtcatc attcaggatg atagccgcct
    29701 tgtcgccggg cctggcgagt taattattat tccggcgaac acgccgctgg agatt
//
LOCUS       DAJVKX010000045        29696 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000045 DAJVKX010000000
VERSION     DAJVKX010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29696
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.045"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(42..1361)
                     /gene="brnQ"
                     /locus_tag="OPY25_002067"
     CDS             complement(42..1361)
                     /gene="brnQ"
                     /locus_tag="OPY25_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HCS0927683.1"
                     /translation="MTHQLKSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AIGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGLLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSAMPLLIYSVVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGPISNALDAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSATLVDQSANGAAILHAYVQHTFG
                     GAGSFLLAALIFIACLVTAVGLTCACAEFFAQYIPLSYRTLVFILGGFSMVVSNLGLS
                     HLIQISIPVLTAIYPPCIALVVLSFTRSWWHNSTRIIAPAMFISLLFGILDGIKASAF
                     GDMLPAWSQRLPLAEQGLAWLMPTVVMVILAIIWDRAAGRQVTSSAH"
     gene            complement(1770..3065)
                     /gene="phoR"
                     /locus_tag="OPY25_002068"
     CDS             complement(1770..3065)
                     /gene="phoR"
                     /locus_tag="OPY25_002068"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HCS0927684.1"
                     /translation="MLERLSWKRLVLELVLCCIPALILSAFFGYLPWFLLAAVTGLLV
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPDDNGQNILNLLRYPEFTQYLKTRD
                     FTRPLHLVLNTGRHLEIRVMPYTDKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMQEQALEGATREKALHTMREQTYRMEGLVKQLLTLSKIEVAPALLLNE
                     KVDVPMMLRVVEREAQTLSQQKHTFTFAVDDSLSVLGNEEQLRSAISNLVYNAVNHTP
                     AGTHITVSWRRAAHGAEFCIQDNGPGIAAEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHALNHHESRLEIDSSPGKGTRFSFVLPERLIAKNSD"
     gene            complement(3135..3824)
                     /gene="phoB"
                     /locus_tag="OPY25_002069"
     CDS             complement(3135..3824)
                     /gene="phoB"
                     /locus_tag="OPY25_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HCS0927685.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNKLNE
                     PWPDLILLDWMLPGGSGLQFIKHLKREAMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPGSHRVMTGDSPLDMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEHSGHDRMVQTV
                     RGTGYRFSTRF"
     gene            4039..5241
                     /gene="sbcD"
                     /locus_tag="OPY25_002070"
     CDS             4039..5241
                     /gene="sbcD"
                     /locus_tag="OPY25_002070"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HCS0927686.1"
                     /translation="MRILHTSDWHLGQNFYSKSRAAEHQAFLDWLLETAQAHQVDAII
                     VAGDIFDTDSPPSYARELYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDILAFLNT
                     TVIASAGYAPRLLHRRDGSPGAVLCPIPFLRPRDIITSQAGLSGSEKQQQLLHAIADY
                     YQQQYQEACLLRGERKLPVIATGHLTTVGASKSDAVRDIYIGTLDAFPAQHFPPADYI
                     ALGHIHRAQCVGGTEHIRYCGSPIALSFDECGKSKCVHLVTFDQGKWQSTESLAVPVT
                     QLLAVLKGDLASITEQLEQWRGVEQSPPVWLDIEITTDDYLHDIQRRIQALTESLPVE
                     VLLVRRSREQRERSLANERRETLSELSVEEVFARRLALEALDTPQRERLNQLFSSTLY
                     ALNEEHEA"
     gene            5238..8379
                     /gene="sbcC"
                     /locus_tag="OPY25_002071"
                     /pseudo
     CDS             5238..8379
                     /gene="sbcC"
                     /locus_tag="OPY25_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
     gene            8552..9724
                     /gene="araJ"
                     /locus_tag="OPY25_002072"
                     /pseudo
     CDS             8552..9724
                     /gene="araJ"
                     /locus_tag="OPY25_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459389.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
     gene            complement(9744..10652)
                     /gene="mak"
                     /locus_tag="OPY25_002073"
     CDS             complement(9744..10652)
                     /gene="mak"
                     /locus_tag="OPY25_002073"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HCS0927687.1"
                     /translation="MRIGIDLGGTKTEVIALDDAGEQRFRHRLPTPREDYQQTIETIA
                     TLVDMAEQATGQTGSVGIGIPGSLSPYTGVVKNANSTWLNGQPFDSDVSRRLKREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVALNGRAHIGGNGTAGEWGHNPL
                     PWMDDDELRYREEIPCYCGKQGCIETFISGTGFATDYQRLSGKTLKGDEIIRLVDAQD
                     AVAELAISRYELRLAKALSHVVNILDPDVIVLGGGMSNVERLYKTVPSLMKSFVFGGE
                     CETPVRKARHGDSSGVRGAAWLWPLA"
     gene            10778..11689
                     /gene="rdgC"
                     /locus_tag="OPY25_002074"
     CDS             10778..11689
                     /gene="rdgC"
                     /locus_tag="OPY25_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HCS0927688.1"
                     /translation="MLWFKNLMVYRLSRDITLRAEEMEKQLASMTFTPCGSQDMAKMG
                     WVPPMGSHSDALTHTANGQIIICARKEEKILPSPVIKQALEAKIQKLEADQGRKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLALENPIELTLTEWVRSGTVAQGFQLLDEAELKAMLEDGGVIRAKKQDLVSDE
                     IAVHIEAGKVVTKLALDWQQRIQFVMCDDGSIKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQSLVEGLGGEAQR"
     gene            complement(11727..12011)
                     /gene="ppnP"
                     /locus_tag="OPY25_002075"
     CDS             complement(11727..12011)
                     /gene="ppnP"
                     /locus_tag="OPY25_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HCS0927689.1"
                     /translation="MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEE
                     MTVVSGALKVLLPGTVEWKVYTAGEVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            complement(12082..12759)
                     /locus_tag="OPY25_002076"
     CDS             complement(12082..12759)
                     /locus_tag="OPY25_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HCS0927690.1"
                     /translation="MSASLAILTIGVVPMSEVLPLLTEYIDEQHITHHSLLGKMSRED
                     VMADYAVEPGDDLLLTLLNDNQIAHVSRQKVERDLQSVVEVLDNQGYDVIILMSTAAI
                     KSTAARNSILLEPLRIIPPLVASIVDGHQVGAIVPVAELLAAQEKKWQVLQMPPVYSL
                     ANPVHGSEQQLIDAGQALLDQGADVIMLDCLGFHQRHRDILQQALDVPVLLSNVLIAR
                     LASELLV"
     gene            complement(13010..13201)
                     /gene="yaiA"
                     /locus_tag="OPY25_002077"
     CDS             complement(13010..13201)
                     /gene="yaiA"
                     /locus_tag="OPY25_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HCS0927691.1"
                     /translation="MPTRPPYPREAYIVTIEKGTPGQTVTWYQLRADHPKPDSLISEH
                     PTAEEAMDAKKRYEDPDKS"
     gene            complement(13228..13773)
                     /gene="aroL"
                     /locus_tag="OPY25_002078"
     CDS             complement(13228..13773)
                     /gene="aroL"
                     /locus_tag="OPY25_002078"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HCS0927692.1"
                     /translation="MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMS
                     VADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCA
                     PVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKAPAQV
                     VSEIIAALPPSTQRLQGDVYT"
     gene            complement(13958..14413)
                     /locus_tag="OPY25_002079"
                     /pseudo
     CDS             complement(13958..14413)
                     /locus_tag="OPY25_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459382.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
     gene            14553..15362
                     /gene="proC"
                     /locus_tag="OPY25_002080"
     CDS             14553..15362
                     /gene="proC"
                     /locus_tag="OPY25_002080"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCS0927693.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQYGINAAQSAQEVAQVADIVFGAVKPGIMVKVLSEISSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPSLVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKIVLET
                     GKHPGELKDMVCSPGGTTIEAVRVLEERGFRAAVIEAMTKCMEKSEALSKS"
     gene            complement(15377..16489)
                     /gene="adrA"
                     /locus_tag="OPY25_002081"
                     /gene_synonym="dgcC"
     CDS             complement(15377..16489)
                     /gene="adrA"
                     /locus_tag="OPY25_002081"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HCS0927694.1"
                     /translation="MFPKIMNDENFYRKAVEQAVAPPDPSDDRQRSGLRFARRIRLPR
                     AVGLGGMLLPVAAVLVSQPVFGGWWLLLVGWSFVWPHLAWQWAAKALDPLRQEIYNLK
                     VDAILSGMWIALMGVNMLPAAALFMMMSMNLMGAGGRRLFTVGMGLLLASCLVTLQLT
                     GLPVAMRSSSLEVTLSLPVIMLYPLLFAWVSYQTAIKLAEHKRRLQAMSSRDGMTGVY
                     NRRHWEILLRNEFDHSRRHHREATLLIIDIDHFKSINDTWGHDAGDEAIIALTRQLQI
                     TLRGSDIIGRFGGDEFAVIMCGTPADSAITAMSRVHERLNTLRLPGAPQVMLRISVGV
                     APLTPQIGHYREWLKSADMALYKAKNAGRNRTEVAA"
     gene            complement(16581..16901)
                     /gene="psiF"
                     /locus_tag="OPY25_002082"
     CDS             complement(16581..16901)
                     /gene="psiF"
                     /locus_tag="OPY25_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HCS0927695.1"
                     /translation="MKITLLVTLLFGLVFLTAVGATEKPLTPQQQRMTTCNQQATAQA
                     LKGDARKTYLSDCLKNSQSAPGEKSLTPQQQKMRECNVQATEQSLKGDDRSKFMSACL
                     KKAA"
     gene            complement(17253..17513)
                     /gene="iraP"
                     /locus_tag="OPY25_002083"
     CDS             complement(17253..17513)
                     /gene="iraP"
                     /locus_tag="OPY25_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HCS0927696.1"
                     /translation="MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNE
                     QEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKLLRHPRH"
     gene            complement(17810..19009)
                     /locus_tag="OPY25_002084"
     CDS             complement(17810..19009)
                     /locus_tag="OPY25_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCS0927697.1"
                     /translation="MESWKVNLISVWFGCFFTGLAISQILPFLPLYISQLGVSSHEAL
                     SMWSGLTFSITFLISAIVSPMWGSLADRKGRKLMLLRASLGMAIAILLQAFATHVWQL
                     FLLRGIMGLTSGYIPNAMALVASQVPRERSGWALSTLSTAQISGVIGGPLMGGFVADH
                     IGLRAVFLITAMLLVVSFLVTLFLIKEGVRPVIKKSERLSGKAVFASLPYPALVISLF
                     FTTMVIQLCNGSISPILALFIKSMMPDSNNIAFLSGLIASVPGISAPRLGKLGDRIGT
                     ERILMATLICAVLLFFAMSWVTTPFQLGLLRFLLGFADGAMLPAVQTLLVKYSSDQIT
                     GRIFGYNQSFMYLGNVVGPLMGATVSAMAGFRWVFIATAAIVLINIGQLTLALRHRRN
                     AQKAKGQ"
     gene            complement(19178..19891)
                     /locus_tag="OPY25_002085"
     CDS             complement(19178..19891)
                     /locus_tag="OPY25_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extensin family protein"
                     /protein_id="HCS0927698.1"
                     /translation="MFMGCENGGRVRGKGFLIIVLLGGIGGLGYRYLPSYYNPFAPLQ
                     LADPPGWITTFKLQRLTPSQCRELLTAANQQGLISSQPVADSAGECPLSHVVRVRDFG
                     QVKLSSSFLASCPLALRSALFVEQQAKPLTETWMQRRLTRIEHLGSYACRNIYHRPDA
                     RRSEHASAEALDVSGFQLSDGRKITVLRGWGREETGPWLRAMLNASCHYYGNGLGPDY
                     NAAHANHFHLGMRGYGVCR"
     gene            19969..21063
                     /gene="ddlA"
                     /locus_tag="OPY25_002086"
     CDS             19969..21063
                     /gene="ddlA"
                     /locus_tag="OPY25_002086"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCS0927699.1"
                     /translation="MAKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKTRFDVVLLGID
                     KAGQWHVNDAENYLQNADDPAHIALRPSAISLAQVPGKHQHQLINAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLSSAACMDKDVAKRLLRDAGLNIAPFIT
                     LTRTNRHAFSFAEVESRLGLPLFVKPANQGSSVGVSKVANEAQYQQAVALAFEFDHKV
                     VVEQGIKGREIECAVLGNDNPQASTCGEIVLNSEFYAYDTKYIDDNGAQVVVPAQIPS
                     EVNDKIRAIAIQAYQTLGCAGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLISRLIELALERHTANNALKTTM"
     gene            complement(21089..21304)
                     /locus_tag="OPY25_002087"
     CDS             complement(21089..21304)
                     /locus_tag="OPY25_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 family protein"
                     /protein_id="HCS0927700.1"
                     /translation="MRLPVKIRRDWHYYAFSIGLIFILNGVVGLLGFEAKGWQTYGVG
                     LVTWIISFWLAGFIIRRREDDEVKDAR"
     gene            21572..21880
                     /locus_tag="OPY25_002088"
     CDS             21572..21880
                     /locus_tag="OPY25_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HCS0927701.1"
                     /translation="MADFTLSKSLFSGKHRETSSTPGNIAYAIFVLFCFWAGAQLLNL
                     LVHAPGIYEHLMQVQDTGRPRVEIGLGVGTIFGLVPFLTGCLIFAVIAAFLRWRHRHQ
                     "
     gene            complement(21918..23012)
                     /gene="yaiW"
                     /locus_tag="OPY25_002089"
     CDS             complement(21918..23012)
                     /gene="yaiW"
                     /locus_tag="OPY25_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HCS0927702.1"
                     /translation="MSAASRLYPLPFLAVAILAGCSSQSGQPVSKGEKPVDVASVVRQ
                     KMPASVKDREAWAKDIATTFKSQGLAPTVENICSVLAVAQQESGYQADPVVPGLSKIA
                     WQEIDRRAERLHIPLFLVHTALKINSPNGKSYSERLDTVKTEKQLSAIFDDFINMVPM
                     GQTLFGSYNPVHTGGPMQVSIAFAEQHAKGYPWNMAGTVRQEVFTRRGGLWFGTYHLL
                     NYPANYSAPVFRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYNSKEPGKTE
                     LAVRKLAGQLGMSEREIRSQLEKGDNLAFEKTALYKKVYKLAEAKTGKTLAREMLPGI
                     QLESPKITRKLTTAWFAKRVDERRARCMGR"
     gene            complement(23027..24247)
                     /gene="sbmA"
                     /locus_tag="OPY25_002090"
     CDS             complement(23027..24247)
                     /gene="sbmA"
                     /locus_tag="OPY25_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HCS0927703.1"
                     /translation="MFKSFFPKPGPFFMSAFVWALIAVIFWQAGGGDWVARLVGASDE
                     VPISAARFWLLDYLIFYAYYLICVGLFATFWFIYSPHRWQYWSILGTSLIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALNSPHKVTLGQFYHEVGVFLGIALIAVVIGVLNNFFVS
                     HYVFRWRTAMNEHYMAHWQYLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPNLPIVGHIPYGLVIAAIVWSLMGTGLLAVVGIKLSGLEFKNQRVE
                     AAYRKELVYGEDDASRATPPTVRELFSAVRHNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGSFQYLINSWTTLVELMSIYKRLRSFERQ
                     LDGQPVQEVTHSFS"
     gene            24583..25740
                     /gene="ampH"
                     /locus_tag="OPY25_002091"
     CDS             24583..25740
                     /gene="ampH"
                     /locus_tag="OPY25_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HCS0927704.1"
                     /translation="MKRSLLFTAMLFAASLTSVQAAQPIADPVFASDIVDRYAEHIFY
                     GSGATGMALVVIDGNQRVFRSFGDTRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGAHVPTYQGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWNWLSTATLKVAPGSQAAYSNLAFDLLADALATASGKPYTQLFEEKITRPLGMK
                     DTTFTPSPDQCKRLMVAEKGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYHR
                     SHQADRMQTLIYQRAQLKKIIGMDVPGKADALGLGWVYMAPKDGRPGIIQKTGGGGGF
                     ITYMAMIPQYNIGAFVVVTRSPLTRFTNMSDGINDLVTELSGNKPIAIPAS"
     gene            complement(25785..26408)
                     /gene="iprA"
                     /locus_tag="OPY25_002092"
     CDS             complement(25785..26408)
                     /gene="iprA"
                     /locus_tag="OPY25_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HCS0927705.1"
                     /translation="MLSLNKPLQEFNRLDKCLSKHGTRFEFVNDKEIICSPDESNTHT
                     FVILEGVVSLVRGDKVLIGIVQAPFIFGLADGVAKKEAQYKLIAESGCIGYRLSSSQT
                     LAIIEQNQLWREAFCWIVWKSQVLELRDKQLIGNNSYDQIRATLMTMIEWDEELRSRI
                     GVMNYIHQRTRVSRSVVAEVLAALRKGNYIEMNKGKLISINRLPSEY"
     gene            complement(26494..29379)
                     /locus_tag="OPY25_002093"
     CDS             complement(26494..29379)
                     /locus_tag="OPY25_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HCS0927706.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANATTYDTFGYHDDAATVFG
                     WDDTNDHDYLTYGGYVYNTPASDSGYFDTKFTGDTVNGVISTYYLNHDYANDTANTLD
                     VTNSTIHGMITSYQMGYGQYVWTNGSDYTTHDWVDDDTFNLNISNSTIDDDFEAFYFT
                     DTYLDSDGKTVKTDYDKLVTAGLGTAITLDVESNINITNNSHVAGIALYQNDLGNSTY
                     TTEAHQWDNTINVANSTVTSGSWSEDEEQGHFGNSSEPSDYNGNGWNKDDVALAFVDD
                     PYSNYRMVNNVTFTDSQLLGDVVLESSWNYNFYSNGRLVDDSTTVYTNGGWADDDQNV
                     DHLTLTLNNTKWVGAAVNDSQSMDPVQFYDVDANSLDPDSTNYDAWGRVNSAASFQSG
                     IFDVSLNNGSEWDTTKTSVIDTLAVNSGSQVDVANGSNLTADTITLNGGSAMNIGEGG
                     YVDTDHLTVDTFSTVTLADDVSSAWSDDALYANTITVTHGGMLDIQTNNTNADSVIDT
                     DTLELTSSNVADNNGNVYAGVFNIHSNDYTLNADLVNDRTWDTTQANYGYGVVAMNSD
                     GHLTINGNGDINNGDEADASSTTDNVVAATGNYKVRIDNATGAGSVADYKGNELIYVN
                     DINTDATFSAANKADLGAYTYQAKQEGNTVVLEQMELTDYANMALSIPSANTNIWNLE
                     QDTVGTRLTNARHGLADNGGAWVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKVDGNN
                     AKWIVGAAAGFAKGDLSDRTGQVDQDSQSAYIYSSARFANNIFVDGNLSYSHFNNDLS
                     ANMSDGTYVDGNTSSDAWGFGLKLGYDLKLGDAGYVTPYGSVSGLFQSGDDYQLSNDM
                     KVDGQSYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYVYDDSNNDADVNGDSIDNGV
                     EGFAVRVGLGTQFSFTKNFSAYTDANYLGGGDVDQDWSANVGVKYTW"
BASE COUNT         7483 a         8014 c         7398 g         6801 t
ORIGIN      
        1 cggggcgtta agccccgtgg tgtacacata tgtcagcgat tttagtgagc gctggaggtc
       61 acctgccgac ccgccgcgcg atcccagata atcgccagga tcaccatcac caccgttggc
      121 atcaaccacg ccagtccctg ttccgccagc ggcaaacgct gactccaggc tggcagcata
      181 tcgccaaagg cagatgcttt gatgccgtca aggataccaa aaagcaggct gataaacatg
      241 gccggcgcga tgatacgggt ggaattatgc caccatgagc gggtaaaact taatacaacc
      301 agtgcgatac acggcggata gatagccgtc agcaccggaa tggagatttg aatcagatgg
      361 ctcagtccga gatttgacac caccatagag aagccgccga gaataaagac cagcgtgcgg
      421 taagacagcg gaatatactg cgcgaaaaac tcagcgcagg cgcaggtcag ccccaccgcc
      481 gtcaccagac acgcgataaa gatcagcgcc gccagcagga agcttcccgc gccgccaaag
      541 gtatgctgaa cgtaggcatg aagaatcgcc gcgccgttcg ctgactgatc gaccagcgtc
      601 gcgctgtcag aacctaagcg aaacaaggca aggtaaagca gcgtcagccc cacgcccgcc
      661 atcaggccgg cccagaccgt gtaacgcgtc aacaggcgcg cttcggtcac gccgcgagaa
      721 cgcgccgcgt tcacaataac gataccaaac accatcgcgc ccagcgtatc catcgtcaga
      781 tagccgttca caaatccgtt agaaaaggcc gcattctgat aagcgtccag ggcgttgctg
      841 attggaccgg caggccaaac gatagccgcg acggacagga tgaccagcgc aataattttc
      901 aacggcgcca ggaaattccc taccgtatcc agcagcttac ccggatagag ggaaaccaga
      961 ataacgatag cgaaatagac cacgctgtaa atcagcaacg gcattgcaga atcgccggtc
     1021 aacggagcga taccgacctc aaacgacacc gtcgcggtac gcggcgtcgc aaataacggc
     1081 ccgacggcca gatagcaaac ggtcgccagc aggagtcccg ccactttacc aatcggcgta
     1141 ctgaggctgt ctacgccgcc gccgactttc gccagcgcca caacagtaag aaccggtagc
     1201 cctacggcgg taatcagaaa gccaatagcg gctgtccaga cgtgttcacc cgcctgcaaa
     1261 ccgaccatag gaggaaagat aatattgcct gcgccaacga acagcgcaaa tgtcataaag
     1321 cccagggcga tgatatcgcg cgattttaac tgatgggtca taaagtctta ctgcctgtgg
     1381 atggtgatgt tgtaaacatt aaaatttttg cctttcccgg aggattataa agcggcgttt
     1441 tttatcaatt tcagcgggaa aaactcccgg accgatgcgg cgaagaattg tttttcgatt
     1501 taccgcgcaa atgcagtcgt aatgacagca cctgaagcgc aatttaaacg cttataacgt
     1561 tttaaagcaa ggtgggatct aaaaaccaga tgaatatcgc gatatgaaat ttacaaccag
     1621 aataaaacac cattctcatg aaaaagttat ggctaatcat gcgaacaaaa aatcaccaaa
     1681 cgttgaatgt ttcaacgagc ccgtcttaac tgcaaagaaa ataagccagc atccgctggc
     1741 ttatggaaag ttatacttac gaaaggcaat taatcactat ttttggcaat taaacgttcc
     1801 ggcagcacaa agctaaatcg cgttcctttg ccaggcgaac tgtcgatttc aaggcggctt
     1861 tcatggtgat tcaacgcatg tttcacaatc gccaatccca ggccgctgcc gcccgtttgc
     1921 cgcgaacgcg ctttatcgac gcggtagaag cgttcggtca gacgaggaat atgctcggca
     1981 gcaatccccg gaccgttatc ttgaatgcaa aattcagcgc catgcgcggc acgtcgccag
     2041 ctcaccgtaa tatgcgttcc cgccggcgta tggtttactg cgttatatac caggtttgag
     2101 atcgcgctac gtagctgctc ttcattgccc agaacgctaa gactatcgtc gaccgcaaac
     2161 gtaaaggtat gtttctgctg gctgagcgtc tgcgcttcac gctccacgac ccgcagcatc
     2221 atcggtacat ccactttttc atttaataac agcgccgggg ccacctcaat tttagacagc
     2281 gtaagcagtt gttttaccag cccttccata cgatacgttt gctcgcgcat cgtatgcagc
     2341 gctttctctc gcgtcgcccc ttccagcgcc tgttcctgca tcatttccag atagccttgc
     2401 aataccgtca atggcgtacg caactcatgg ctaacgttgg cgaaaaagtt acgtctggcg
     2461 ccttcaagct gatgcatttg cgtcacatcg cgcgccacca tcaggagttg tttatcggta
     2521 taaggcatga cgcggatctc cagatgccgc ccggtattga gcaccaaatg aagcggacgg
     2581 gtgaaatcac gcgtttttaa atactgggta aactccggat aacgcagtag attgagaata
     2641 ttctgcccgt tgtcatccgg ccagcgtagc cccagtatct gttgcgccaa accgttacac
     2701 caaaaaatgc cgccctcttc tgtggtcagt accacggcat caggcagcga ctccgcgccg
     2761 ctgcgaaaac gtttaatcag gttccccagc tcgcggcgac gcttcttatt tcgcaactgc
     2821 atctggtgta aaccgtataa cagcggttcc caacttcccc gccccggcgg cggcgtcata
     2881 cttctgtcga cccaaagcca ccaggagagg cgtaacaaat tccagaaatg ccagacaagc
     2941 agtcccgtca ccgccgccag taaaaaccac ggcagataac caaaaaaagc gctaaggata
     3001 agcgcgggga tgcaacagag caccagctcc agcaccagcc ttttccatga cagccgttcc
     3061 agcacgcgtc atactccctc aagaatggaa agccttctcc gccagaaacc tgtgatcaac
     3121 tggcggaaaa ggcattaaaa gcgggtcgaa aaacgatacc ctgtcccgcg taccgtttgc
     3181 accatccggt cgtggccgct gtgctccagc gccttacgca aacggcgaat atgcacgtcg
     3241 accgtccggt cttcaacgta cacattggtg ccccagacat gattgagcag ctgttcgcgg
     3301 ctgtaaaccc gttccgggtg cgtcataaag aaatggagta atttaaattc ggtcggcccc
     3361 atatccagcg ggctgtcgcc ggtcatcacg cggtgagagc caggatcaag gctcagtccc
     3421 tgcatctcga tcacctcttc gaccgccatc ggcgagatac gccgcataac ggctttaatg
     3481 cgcgccacca actccttggg ggaaaacggc ttggtaatgt aatcgtcagc gccggtttcc
     3541 agcccgcgca cacgatcttc ttcctcacct ctcgcggtca gcataaccac aggaatatcc
     3601 cgggtcatgg cctcacgttt gagatgttta ataaactgta accctgaccc gccgggcaac
     3661 atccagtcaa gaaggatgag atccggccag ggttcattaa gtttattcac cgcactgtca
     3721 taatcttcgg cttctacggg ctgaaagcca ttttgttcga gcacgaagca caccatttca
     3781 cggatcggcg cctcatcttc tacgaccaga atacgtctcg ccataatttg ccctgttagt
     3841 cgttagttat caatgccgcg ccattatgcg tcagatttat gacagattta tgaaaaaaaa
     3901 aggcggcatt gacagcatgt tgatgattta tgacaccggt gaaaccgtgc attaccgtgt
     3961 accggcggta aattgcgccc aaaaatggag gggatgacgt gtataatccc gttcacgctt
     4021 tttttgcatg gaacaattat gcgcatcctc cacacctctg actggcatct gggacaaaac
     4081 ttctacagta aaagccgcgc cgcggagcat caggcttttc tggactggct gctggagacc
     4141 gcgcaggccc atcaggtgga tgccattatt gtcgctggcg atatttttga taccgattcg
     4201 ccgccaagct atgcccgaga actttataac cgtttcgtcg ttaatttaca gcaaacgggc
     4261 tgtcatctgg tggtgctggc cggtaatcat gattccgtcg ccacgctaaa cgaatcgcgc
     4321 gacattctgg cgtttctcaa tacaaccgtg atcgccagcg cgggctatgc gcctcggcta
     4381 cttcatcgtc gcgacgggtc tccgggcgcc gtactgtgcc ccattccctt tttgcgcccg
     4441 cgcgacatta ttaccagtca ggcgggatta tccggcagcg agaaacagca gcaacttctt
     4501 catgcaattg ccgattatta tcaacagcag tatcaggaag cgtgcctgct acgcggcgaa
     4561 cgaaagctgc cggttatcgc aacgggacat ttaaccaccg tcggcgccag caaaagcgat
     4621 gcggttcgcg acatttatat cggtacgctg gatgcctttc cggcgcagca tttcccccct
     4681 gcggattata tcgcattggg acacattcac cgcgcgcaat gtgtcggcgg cacagagcat
     4741 atccgctatt gcggctcgcc catcgccctc agctttgatg agtgcggcaa aagcaaatgc
     4801 gtgcatctgg tgaccttcga ccagggaaaa tggcaaagta ccgaaagtct ggctgtcccc
     4861 gtgactcaac tgttggcggt tttaaaaggc gacctggcgt caattaccga acagcttgag
     4921 cagtggcgcg gcgttgagca atcgcccccc gtctggctgg atattgaaat caccaccgat
     4981 gattatctgc atgatatcca acgcagaata caggcattaa cggagtcact ccccgtagag
     5041 gtattactgg tgcgccgtag ccgcgaacag cgtgagcgct cgctggcgaa cgagcggcgg
     5101 gaaacattaa gcgagcttag cgtggaagag gtttttgcgc ggcgtctggc gctggaagcg
     5161 ttagataccc cgcagcgcga gcgcctgaat cagctctttt ccagcacgct ctacgcgttg
     5221 aatgaggagc atgaggcatg aaaattctca gtttgcgtct gaaaaacctg aactcgctga
     5281 aaggagaatg gaaggtcgac tttaccgccg aaccgtttgc cagtaacggg ttattcgcca
     5341 ttaccggccc gaccggcgcg ggaaaaacca ccttgcttga cgccatctgc ctggcgctgt
     5401 accacgaaac gccgcgcctg aatacggtat cgcaatcgca aaacgatttg atgacgcgcg
     5461 atacggcgga atgtctggcc gaagtggagt ttgaggtaaa aggcgaagcc tggcgcgcgt
     5521 tctggagcca gaaccgagcc cgaaatcggc ctgacggcaa tctccaggcc ccacgcgtgg
     5581 agctggcgcg gtgttcagac ggaaagatct ttgccgataa ggtaaaggat aaactggaga
     5641 tgatcgccac gttgaccggg ctggactacg ggcgcttcac ccgttcaatg ttgttatcac
     5701 aggggcagtt cgccgccttt cttaacgcca aagcgaaaga gcgcgcagag cttctggagg
     5761 agctcaccgg cactgagatt tacgggcaga tctccgcaca ggtatttgaa aaacataaat
     5821 cagcccgtct cgaactggaa aagttacaag cgcaggccag cggcgtcgcc ctattggcgg
     5881 acgaacagtt acagcaactg gaagccagtt tgcaggcgct tactgacgaa gagaaacgcc
     5941 tgctggccga ccagcaggga cagcagcagc accttcactg gctgacccga aaaaacgagc
     6001 tccacactga attacacgcc cgacagcagg cgctgtacgc ggcgcaagag gcgcgagaaa
     6061 aagcgcagcc gcagctcgcg gcgctgacgc tggcgcaacc tgctcgccag ttgcgtccgc
     6121 attgggagcg cattcaggaa caaacccgcg ccgttgagcg tgttcgccag cacagtgatg
     6181 aagtgaatgc tcgcttacaa agcgcgtatc gcctgcgcca gcgtatccgc gcctgcgcgc
     6241 atcgacaatt cacgcaactg aacgccacag ggcagcggtt gaagacatgg ctggcggaac
     6301 acgacggcat ccgcgtctgg cgcagcgaac tggcggggtg gcgagcatta ttaacacaac
     6361 aatcccacga ccgggcgcaa ctgagccaat ggcaacagca gttgctgagc gatatgcgtc
     6421 agcgtgatgc gctaccgccg ctcacgctcg acctcacgcc acaggcgctg gcggaagcca
     6481 gggcattgca tacccggcag cgtccgctac gccatcgtct cgccgcgctt caggggcaaa
     6541 ttctcccgaa acaaaagcgt caggcgcagc tacaggcagc tatcgcgcgt catcatcagg
     6601 agcagacgca atacacccaa cgtctggcag ataagcgcct gagttataag actaaagcgc
     6661 aggagcttgc ggacgttcgc actatttgcg agcaggaggc gcgcatcaaa gatctggaaa
     6721 gccagcgggc gcacttacag tccggccagc cgtgtccgct ttgcggctcg acgacgcacc
     6781 ccgccatcgc cgcctatcag gcgctggaac tgagcgcgaa tcaaacccgc cgcgacgcgc
     6841 tggaaaaaga ggtcaaaacg ctggcggaag aaggcgctgc gctgcgagga cagttagatg
     6901 ccttaacgca acaattacag cgggatgaaa gcgaggcgca gtcgttgttg caggaggagc
     6961 aagcgcttac tgaggaatgg caaacgctgt gcgctacgct gggcgttcag ctccagccgc
     7021 aagaagacct cgctggctgg ctgaccgccg cggaagagca tgagcaacag ttggatcagc
     7081 tcagccagcg tcatgctcta caaacgcaaa tcgcggcgca tactgaacag gtagcgcgct
     7141 ttaccgcgca gattgcacag cgtcaggcgt cgctgacggc tgatttggcg cagtatacgc
     7201 tttcccttcc tgcgccagaa gacgaggcat cctggctgaa tgagcgcgcc gacgaagcga
     7261 aaatatggca acagcgtcag acagagttcg cggatttgca aacgcagatc gacaggcttg
     7321 ccccgttgct ggagacgcta ccgcaaacgg ataccgcgga ttccgacgac gacgtgccgc
     7381 tggataactg gcggcagacg catgatgagt gcgtgtcatt acaaagccag ttgcaaaccc
     7441 tgcaggaaca gacgacgcag gaacagcagc gcgccgccga ggcgatagcg cactttgatg
     7501 cggcgttaaa aaatagcccg tttgacagcc aggcaacgtt cctggcggcg ttgctggatg
     7561 aagagaccgt gacccgtctg gaaaaacaac aacaaacgct ggaaagtcag ctacaacaag
     7621 cgaaggcgtt aagcgcgcag tccgcgcagg cgctggctga ccatcagcaa cagccacccg
     7681 ccggtctgga cccaacgtgt acggcggagc agctcgcgca gcggctggcg cagttggcgc
     7741 aacaactgcg cgagaacacg acacgccagg gggaaatccg ccagcaaatt aaacaggatg
     7801 cagataatcg gcagcgccaa cgggcgctga tggcggaaat gaagcaagcc tctcagcaag
     7861 tggaagactg gggctatctc aatgcgctga tcggctctaa agaaggtgat aagttccgca
     7921 aattcgccca gggactgacg ctggataatc tggtctggct ggcgaatcat cagctcaccc
     7981 gcctgcatgg ccgctattta ttgcagcgca aagccagcga cgcgctggaa ctggaggttg
     8041 tcgatacctg gcaggccgac gccgtgcgcg atacgcgaac gttatcaggc ggcgaaagct
     8101 tcctggtcag cctggcgctg gcgctggcgt tatcagattt ggtcagccat aaaacgcgca
     8161 ttgattcctt gttcctggac gaaggcttcg gcacgcttga tagcgaaacg ctggacgccg
     8221 cgctggatgc gctcgacgcg ctgaatgcca gcgggaagac catcggtgtg attagccacg
     8281 tggaagccat gaaagaacgt atccccgtgc agataaaagt gaaaaaaaat caatgggctt
     8341 ggttatagca aactggacaa agcgtttgcc gtggagtaac gcgagtgtca tcctgcgcac
     8401 agcataccgt catgacatag cataataatg aatacacaaa gacgaataag gaatggtatt
     8461 acctcgcgct tatccgcaag ctatacgttg attggctgtg acaattcata gccacagcgc
     8521 gcgacatgcg tcttcatttt cggcaggtgg tatgaaaaaa gttatttttt ctttggcgct
     8581 gggtacgttc ggactgggga tggccgagtt tggcattatg ggcgtgctga cggagctggc
     8641 acgcgatgtc gggataacga ttcccgccgc cgggcatatg atctcgtttt acgccttcgg
     8701 cgtcgtgctg ggcgcgcctg taatggcgct cttttccagc cgcttttcgc ttaaacatat
     8761 actgctgttt ctggtcatac tgtgcgtgat gggcaatgcc atatttacct tttcctcgtc
     8821 atatctgatg ctcgccgtcg gcagactggt ttccggcttt ccacacggcg ccttttttgg
     8881 cgtcggtgcc attgtcttgt caaagattat ccgccccggg aaggtcaccg ccgccgtcgc
     8941 gggtatggtt tcagggatga cggtggcgaa tctggtgggc attccgttcg gcacttacct
     9001 gagccaggaa tttagctggc gctacacctt tttattgatc gcggttttca acatcgccgt
     9061 gctcaccgcg attttcttct gggtgccgga tattcgcgac aaagcccaag gcagcctgcg
     9121 cgagcagttc cacttcttgc gtagccccgc gccgtgactc attttcgccg ccacgatgtt
     9181 cggcaatgcg ggcgtttttg cctggttcag ctatatcaag ccatttatga tgtacatctc
     9241 cggtttttcg gagacgagca tgacgtttat tatgatgctg gtcgggctgg ggatggtgtt
     9301 aggcaatctg ttaagcggca aactctccgg tagatatacg ccgctgcgca tcgcggtagt
     9361 gactgacctc gttatcgtgc tctctctcat ggcgctcttt ttcttcagcg gatacaaaac
     9421 ggcatcgctg actttcgcgt ttatctgctg tgctggtctg tttgcgctct ctgcgccgct
     9481 gcaaatcctg ctgctgcaaa acgccaaagg cggcgaactg ctgggcgcgg cgggagggca
     9541 aatcgcgttt aatctcggta gcgcgattgg cgcctggtgc ggcgggctga tgctgacgct
     9601 aggttttgcg taccactatg tggcgcttcc cgccgccctg ctctcgtttt ccgccatgtc
     9661 gtcgttgctg gtatacggac gtctaaaaca caagcagcca tcggtcacgc cggttgccgg
     9721 atgacgccat ccggctagaa acgttacgcc agcggccaca gccaggccgc gccgcgcacg
     9781 ccgctcgaat cgccatgccg cgccttacgt accggcgtct cgcactcgcc gccaaaaaca
     9841 aacgatttca tcagcgacgg aaccgttttg tacaggcgct caacattgct cataccgccg
     9901 cccagcacaa tgacatccgg atccagaata ttcacgacat gagataatgc cttcgccagc
     9961 cgtagctcat aacggcttat cgccagttcc gccacggcgt cctgcgcgtc gaccagacga
    10021 ataatctcat cgccttttag cgttttaccg ctcaaacgct ggtaatccgt ggcgaatccc
    10081 gtaccggaaa taaaggtttc gatacagcct tgtttaccgc aataacaggg aatttcttcg
    10141 cggtaacgca actcatcgtc atccatccac ggcaacggat tgtggcccca ttcgcctgcc
    10201 gtaccgttgc cgccgatgtg cgcccggcca tttagcgcta cgcccgcgcc gcacccggta
    10261 ccgataatca ccgcaaatac cgtttgcgcc cccgccgccg cgccatctac cgcctctgat
    10321 accgccaggc aattggcatc gttggctaac cgcacttcac gcttcagacg acggctcaca
    10381 tcgctatcga acggctggcc gttaagccac gtagagttag cgttttttac cacgccggtg
    10441 taaggcgaga gagaaccggg aatgccaatg ccaacgctac cggtctggcc ggtcgcctgt
    10501 tccgccatgt cgaccagcgt agcgatggtt tctatcgttt gctgataatc ctcccgcggc
    10561 gtaggcagac gatggcgaaa ccgctgctct cctgcatcat caagcgcaat gacttccgtt
    10621 tttgtgccgc ctaaatcgat accaatacgc acataccgct cctcattttt tgggaatatc
    10681 aacagggtag aattcaccgt tctgattggc aatgcaagcc tgccgacaat tcgttactat
    10741 accgactgga tttaacgaca aggccgtgga aattatcatg ctgtggttca aaaatttaat
    10801 ggtttaccgt cttagccgcg atatcacatt acgcgccgaa gagatggaga aacagctcgc
    10861 ctcaatgacg tttaccccat gcggtagcca ggatatggcc aaaatgggct gggttccgcc
    10921 gatgggctct cacagcgatg cgttaacgca caccgccaat ggccaaatta ttatttgcgc
    10981 gcgcaaagaa gagaaaatcc tgccatcgcc agtgatcaaa caggcactgg aggcgaaaat
    11041 ccagaaactg gaagccgatc agggacgcaa gctgaagaag acggaaaaag attccctgaa
    11101 ggatgaagtg ttgcattcgt tgctgccgcg cgcgtttagc cgcttcagtc agacaatgat
    11161 gtggattgat accgttaacg gcctgattat ggttgactgc gccagcgcga aaaaagcgga
    11221 agatactttg gcgctactgc gtaaaagtct tggctcgctg ccggtcgtcc cgctggcgct
    11281 ggaaaatccg attgagctga cgctcaccga gtgggtgcgc tccggtacgg tcgctcaggg
    11341 tttccagttg ctggacgaag ccgaattgaa agcgatgctg gaagatggcg gcgtgatccg
    11401 cgcgaaaaag caggatctgg tcagcgacga gatcgccgtt catattgaag cgggtaaagt
    11461 ggtcacgaag ctggcgctcg actggcagca gcgtattcaa ttcgtcatgt gcgacgacgg
    11521 ctccattaag cgtctgaaat tctgcgatga gctgcgcgat cagaacgaag atatcgaccg
    11581 ggaagatttt gcccaacgtt ttgatgcgga ctttatcctg atgaccggcg agctggcggc
    11641 gctgattcaa agcctggtgg aaggattagg cggcgaagcg cagcgctaac cagagggtcc
    11701 ctctccgccg gagaggggac tcaccgttac aaatagcggc acagatacga ggtgggctca
    11761 gcgacctgta gatgaaactc gctgtggcca ggcacgttaa acacctcacc ggctgtatac
    11821 actttccatt cgacagttcc cggcaacagt accttcaacg cgccgctcac aaccgtcatc
    11881 tcttcgggtt cggcggtgcc aaatgtatac tccccttccg ccatcacacc aacgctggcc
    11941 cggccggtgc tactgctggt aaatccaata gacttcactt tcccggaaaa gtattcattg
    12001 ctttgtagca taatcaggcc ccgtctcatt attaaattaa cacccaatat agagtcctga
    12061 cgttcggcct gtcacgtaaa attagacaag cagttctgaa gctaaccgcg caatcaaaac
    12121 attagagagt aaaaccggca catccagcgc ctgctgtaaa atatcccgat gacgctgatg
    12181 aaaacccaga caatccagca taatgacgtc cgcgccttga tccagtagcg cctgcccggc
    12241 atcaattaac tgttgctcag aaccgtgaac cggattcgcc agcgaataca ccggcggcat
    12301 ttgcaatacc tgccattttt tctcctgggc cgccagaagt tctgcaacag gcacaatcgc
    12361 gcccacctga tgtccatcca caatagaggc gacaagcggt ggaataatac gcagcggttc
    12421 aagcaaaata gaattacggg ctgccgtact tttaatcgcc gcggtgctca tcagtataat
    12481 gacatcgtaa ccctgattat ccagcacctc gacaacgctc tgtaaatctc gctccacttt
    12541 ctggcgggaa acatgggcta tctggttatc attcagcaac gtcaaaagca gatcgtcgcc
    12601 aggctctaca gcgtaatccg ccataacgtc ttcccggctc atttttccca gcaggctatg
    12661 atgggttatg tgttgttcgt cgatgtattc cgtcagaagc ggtaacactt cgctcattgg
    12721 cacaacgccg attgtgagga ttgccaacga cgcactcatt tttattccac cttattactt
    12781 cgtcgtaatt cccgggcaaa tattcacacg ctcaccgcgc tacctgccct acaaatctca
    12841 gaaagcgtag cagcagatga gcaacgtatt gtgtaaagat tccaaataac tccaatattg
    12901 tattgttatc gcttaattta tggttttagt tgccagtata aatgtttcaa gaatgtgatg
    12961 gagatacaat ttaggggtac tcagaatccc ttccgagtgg ttcatgcgtc tatgatttat
    13021 ccggatcttc gtaacgtttt ttcgcatcca tcgcttcttc tgcggtcgga tgctcgctga
    13081 tgagcgaatc aggtttcgga tggtcagccc gtagctgata ccacgtcacc gtctggcccg
    13141 gcgtgccttt ttcaatggtg acgatataag cttcccgcgg ataaggtggt ctggttggca
    13201 tagcgtttcc tttattctgg gtgagcgtta agtatagaca tctccctgta accgttgcgt
    13261 cgacggcggc agcgccgcaa taatttcaga aacgacctgg gccggcgctt tcgtcgcgtc
    13321 aataatgtaa tgcgccgttt cgcgatacaa cgcgtcacgc tgctcaagca cttcccgaac
    13381 ctcttcgctc aacggcttgc cggtgagggt cgggcgcaga tccgcttcag gttcagcctc
    13441 aagccggtta accagcgtgg ataccggcgc gcacagataa atcactacgc caacacggtg
    13501 catataacgt cggttatact ccgtgagaat aataccgcct cccgtcgcca cgacagtcga
    13561 aggcgcgctt accgcctcca gggccgcggt ttcccgggcg cggaaccctc cccagccttc
    13621 tttttcaacg atatcagcga cgctcatctg cacgtgcgat tgcagccagc ggtcggtatc
    13681 tgcaaaccga aaaccggttg cctgcgccag cgccataccg atggtggttt tcccacagcc
    13741 ccgcgggcca acaagataaa gaggttgcat catagcaggc gttcccccag gaactgcgca
    13801 tacgcaggat ttgatatcag taatgttata atcatatcat ctaactagta caacgcataa
    13861 atgtaaataa taatttacac aaaggtacta aagtcacaat attagtacta tagcaagaat
    13921 cagaaatgaa taaactgtaa atttttcatt acatgattta ttttttacgc tggctttcca
    13981 gccaccactt atccagctcg gcggcaaaat gctgacgatc gcgcggcgag agagtgtttg
    14041 gtccccccgt ttgtacgccg ctggcgcgta gcgtgtccat aaagtcacgc atcgtcagac
    14101 gttcgcgaat cgtggcgtcg ctatagcgtt ctccccgggg attaagagcc gcagcgcctt
    14161 tttccagcac ttcagccgcc agcggaatat ccgcggtaat caccagatcg cccgcttcgc
    14221 attgacgcac aatttcattg tccgccacgt caaacccggc ggccacgcga agcgtgcgga
    14281 taaaacgcga aggcggcacg cgcaaggcct gattggcaac cagaataagc ggcaactgca
    14341 tccgctcggc ggcgcggtac aaaatttctt taatgacatt cggacacgca tccgcatcca
    14401 cctagatggt cataatgtct cccgtacggt atacaatctt ttattgtctc gcgcttttgt
    14461 ctttcatcaa agtgctgttt ctccttctgc ccgttttcaa tccgcgttaa gctaaccatt
    14521 ccccataaca cacaaacata gggagtgacg agatggagaa gaaaatcggt tttattggct
    14581 gcggtaatat gggcaaggct attcttggcg gactgattgc cagcggtcag gtacttcccg
    14641 gccagatctg ggtctacacc ccctcccccg ataaagttgc cgccctgcat gatcagtacg
    14701 gcattaatgc ggcgcaaagc gcgcaggagg tcgctcaggt cgcggatatc gttttcggcg
    14761 cggtaaaacc gggcattatg gtgaaagtgc tcagtgaaat ctcctccagc ctgaacaaag
    14821 actcgctggt ggtctctatc gccgcaggcg taacgcttga tcagcttgcg cgcgcgctgg
    14881 gacacgaccg taaaatcatt cgcgctatgc cgaatacgcc gtcgctggtc aacgcaggaa
    14941 tgacctccgt cacgcccaac gcgctggtca caccggaaga tacggctgat gtgctgaata
    15001 ttttccgctg ctttggcgag gcggaagtga ttgctgagcc gatgatccat ccggtggttg
    15061 gcgtgagcgg atcttcgccg gcctatgtct ttatgtttat cgaggcgatg gcggacgctg
    15121 ccgttctggg cggtatgcct cgcgctcagg cttataaatt cgccgcgcag gccgtcatgg
    15181 ggtcggcgaa aatagtactc gaaaccggaa agcatcccgg cgaactgaaa gatatggtgt
    15241 gctcgcctgg cggaacgacg attgaagccg tacgcgttct ggaagaacgt ggcttccgcg
    15301 ctgcggtaat agaagcgatg acgaaatgta tggaaaaatc agaggcgctc agtaaatcct
    15361 gaagcccggc tggacgtcat gccgccactt cggtgcggtt acgtccggca ttctttgctt
    15421 tgtaaagcgc catatccgca gactttaacc attcccgata atgaccgatt tgtggcgtta
    15481 acggcgccac gcccacgctg atacgtaaca tgacctgcgg cgcgcccggc aagcgtaagg
    15541 tatttagccg ttcatgcact cgcgacatgg cggtaatcgc gctgtctgcc ggcgttccgc
    15601 acataatcac cgcaaattcg tcgccgccaa agcgcccgat aatatcactc ccgcgtagcg
    15661 ttatctgtaa ttgacgcgtc agggcgataa tagcctcatc cccagcatca tgtccccagg
    15721 tgtcgttaat gctcttaaaa tgatcgatat cgataatcaa caatgtcgcc tcccgatggt
    15781 ggcgtcggct gtgatcgaat tcattacgta ataaaatttc ccagtggcgt cggttataga
    15841 cgccggtcat gccatcccgc gaactcatcg cctgcaagcg tcgcttatgt tccgctaatt
    15901 taatggccgt ttgataactt acccaggcga acagaagcgg atacaacata atgacgggca
    15961 aagagagcgt gacttccagc gacgagcttc gcatcgcgac gggtagcccg gtaagctgca
    16021 acgtcaccag acatgacgcc agcaaaaggc ccattccgac agtgaatagc cgccgcccgc
    16081 cagcgcccat cagattcatg ctcatcatca taaacagcgc ggcggcaggc aacatattga
    16141 cgcccatcaa cgcgatccac atgccggaga ggatcgcatc cactttcagg ttgtaaattt
    16201 cctggcgtag cggatcaagg gctttcgccg cccactgcca cgccagatgc ggccagacaa
    16261 aagaccagcc gaccagcaat aaccaccagc cgccaaagac aggttgcgac actaacacgg
    16321 cggccaccgg taaaagcatc ccccctaacc ccaccgcgcg cggtagcctg atgcgccggg
    16381 cgaagcgcaa tccggagcgc tgacgatcat cagaagggtc aggcggcgct accgcctgct
    16441 caaccgcttt tcggtaaaaa ttttcatcat tcattatttt tgggaacatt tagaaacaat
    16501 tttcccaaat tatagaaaca gagcgcatgg agggagtatg aaatttcggg tgagtgtttt
    16561 tcagggctca cccgatagca ctacgccgct tttttcaggc aggcgctcat aaacttgcta
    16621 cggtcatcgc ctttcagtga ttgttccgtc gcctgaacat tgcattcacg cattttctgc
    16681 tgttgcggcg tcaggctttt ctcgccaggg gctgactggc tgtttttcag gcagtcgcta
    16741 aggtaggttt tacgcgcatc gcctttcaac gcttgcgctg tcgcctgctg attacaggtc
    16801 gtcatgcgct gctgttgcgg cgttaacggt ttctcggttg cgccgacggc ggttaaaaag
    16861 accaggccaa aaagtaaagt caccagtaat gttattttca tagcaccatc cttttgtcag
    16921 tgtacacatt acacgttgtc cctttgggaa atatcccagg gactttatat aagtctggct
    16981 gttactggca aaaataccac ccggcagtaa aagtattact taccgttagc aatatatgtt
    17041 ttattgattg acaaaccgta ggctaatgtg caactcgatt atccacagtc acactggcag
    17101 gatgcagaag aacagcgcat aacgttacac tgttattacc atagccgctt cgtttttatt
    17161 ttgctctgta ttaaccagaa gaaaataaaa acgaagcggc tatgttattt cataaaagta
    17221 acgttataac aactgtgttg ttttaaatac gattagtgcc gggggtgtct cagcaacttt
    17281 tttacatatt ggcgcagcaa ttccgtatcg tgatcaggaa cgctggcatc cggctttacg
    17341 ccttcaagtg ccccctctac ctgacgtatc aacatctcct gctcgttttg cgccatgtta
    17401 cgtaacattg ctgtgacgat aatctctaac gcttctacct gagcaaccag ttctttcgac
    17461 tcttcttctt tttgggctag cttaagcaac aactctgcta tgagattttt catgaccata
    17521 tttccttatt agttccaggg tgacgttatc actatgaaga accactgcct agaggctgaa
    17581 agtactattt ttatgataca ggaagaactt tacacaaata attatcactg tcgccgcagc
    17641 gaaacgtttc tcagaccgaa aacgagacga taataaacca tcaaaaaaca ataatcacgc
    17701 tatatcataa tttaaggtta tgccatctat agaaaaactt cacggataaa gagtatatct
    17761 tttaatttaa accatatcgt aacggcagaa gcgccgttac gatgcaccgc tattggcctt
    17821 tcgctttttg cgcgttacgc cgatgacgta acgccagggt cagttgtcca atattgatca
    17881 acacgatcgc cgccgtagcg ataaaaaccc agcggaaacc ggccatcgcc gataccgtcg
    17941 cgcccatcaa cggcccaacc acgttgccca ggtacataaa tgactggttg tagccaaaaa
    18001 tacgtccggt aatttgatcg ctggagtatt tcaccaataa cgtttgtacg gcgggtaaca
    18061 tcgcgccatc ggcaaagcct aacaagaaac gtaacagccc cagctggaac ggcgtggtga
    18121 cccaggacat cgcgaagaaa agcagcactg cgcagataag cgtggccatc agaattcttt
    18181 ccgtgccgat tctgtcgcca agttttccca ggcgaggcgc ggagataccg ggcaccgagg
    18241 cgattaaccc gctaagaaag gcgatgttat tactgtccgg catcattgat ttgataaaca
    18301 gcgccaggat tggactgatg gaaccattac agagttgaat gaccatcgtg gtaaaaaaca
    18361 aactgatcac cagcgcagga taaggtaacg acgcaaaaac ggctttaccg ctcaggcgtt
    18421 cgcttttctt gatgaccgga cgcacgcctt ctttaattaa aaatagcgtg accagaaagc
    18481 tcaccaccaa cagcatggcg gtaatcagaa ataccgcccg cagcccgata tgatccgcga
    18541 caaagccgcc cattaacggc ccgccgataa cgccgctgat ctgcgcggta gaaagcgtac
    18601 tgagcgccca gccgctacgt tcgcgcggta cctgagaggc taccagcgcc atggcattgg
    18661 ggatatagcc tgacgttaac cccatgattc cgcgcagcag gaaaagttgc cagacatggg
    18721 tcgcgaatgc ttgcagtaga atagctatcg ccatcccgag cgacgcgcgc aatagcatca
    18781 gtttacgccc tttacgatcg gcgagactgc cccacatcgg cgatacaatg gcggaaataa
    18841 gaaacgtgat gctaaacgtt aacccggacc acattgataa cgcttcatgg gaagagacgc
    18901 caagctggga aatatacagg ggtaaaaatg gcaggatttg gctgattgcc agcccggtaa
    18961 aaaaacatcc aaaccaaacg gaaattagat taactttcca ggattccata agactcgtaa
    19021 cggtaagtag ctgaaaatac gcgttagctt agcaagctct cattttcctg gtggttccag
    19081 aggtgcgata cgtcacactt tgctattttg tctccccgtt catcattttt gtgaaacata
    19141 tcacattata tagccgcgaa aggcagacgt ttatgcttta acgacacacg ccgtagcccc
    19201 gcattccaag atgaaaatgg ttagcatgag cagcgttata gtcaggcccg agcccattgc
    19261 cataataatg gcaactggcg tttaacatag cgcgtaacca gggccccgtc tcctcacgcc
    19321 cccagccgcg caggacagtg atttttcggc catctgatag ttgaaacccg ctgacatcca
    19381 gcgcttctgc gctggcatgt tcactgcgac gcgcatccgg acggtgataa atattacggc
    19441 aggcatagct gcccagatgt tcgatgcggg tcaggcggcg ctgcatccac gtttctgtta
    19501 aaggttttgc ctgctgttcg acaaacagcg cggaacgcag cgccaacggg caggaggcta
    19561 aaaaactgct gctcagtttt acctggccaa aatctctgac gcgcacaaca tgggacaagg
    19621 gacattcacc agcgctatcc gcaacaggtt gtgatgaaat taatccctgt tgattggccg
    19681 ccgtcaacag ctcccggcac tgcgacggcg tcaggcgctg tagtttgaag gtagtgatcc
    19741 agcctggcgg atcggcaagt tgtagcggag caaaaggatt ataataagag ggaagataac
    19801 gatatcccag cccgccaata ccgcccaaca gcacaataat cagaaaaccc ttacctctca
    19861 cgcggcctcc gttctcacat cccataaaca ttatggcaga agcccgcgaa acccgcgttt
    19921 tgtcgtggta atgtatacgc tttgcattcg atggaatggg tttttaagat ggcgaaattg
    19981 cgggtaggaa tagtatttgg cggtaagtcg gcggaacatg aagtgtcttt gcaatcagcg
    20041 aaaaatatcg ttgatgcgat cgataaaacc cgcttcgacg tggtgctgtt agggatagat
    20101 aaggcgggac aatggcatgt taacgatgcg gaaaattatt tgcagaatgc agacgatccg
    20161 gcacatatcg cgctacgtcc ttcggcaatc agtctggccc aggtgcctgg caaacaccaa
    20221 caccaattga ttaacgctca gaacgggcag ccgctaccga cggtagatgt tatttttcct
    20281 atcgtccacg gtacgctggg cgaagacggc tcattgcagg ggatgctgcg cgtcgcaaac
    20341 ttaccgtttg tcggttcaga cgtgctgagc tccgcagcct gcatggataa agacgtcgcc
    20401 aaacgactgc tacgcgatgc aggactgaat atcgccccgt ttattacact cacccgaacg
    20461 aatcgtcacg cgtttagttt tgccgaggtt gaatcccgtc tgggactgcc gctgttcgtt
    20521 aagcccgcca atcagggctc ttcggtcggc gtcagtaaag tcgctaacga agcgcaatat
    20581 cagcaggcgg tcgcgctggc tttcgaattc gatcataaag tggtggtgga gcaagggatc
    20641 aaagggcgcg agatcgaatg cgccgtatta ggtaacgata acccacaggc cagtacctgc
    20701 ggcgaaatcg tactgaacag cgaattttac gcctacgata ctaagtatat tgatgataat
    20761 ggcgcgcaag ttgtcgtgcc tgcgcagatc ccttccgagg tgaatgacaa gatccgcgcg
    20821 atcgcgatcc aggcttatca gacgctgggg tgcgcgggta tggcgcgtgt cgatgtcttc
    20881 ttaacggcag acaatgaggt cgtgattaac gagattaata cgctgccagg ttttaccaat
    20941 atcagtatgt atccaaaact ctggcaggcg agcggattgg gctataccga tttgatcagc
    21001 cgcctgattg agctggcgct ggaacgccat acggcgaata acgccttaaa aaccacgatg
    21061 taatagcgca cgcccgatag cgcaacgttt atcgggcgtc ttttacctca tcatcttcgc
    21121 gccggcgaat gatgaacccc gccagccaga agctgataat ccacgttacc agcccaacgc
    21181 cataggtttg ccatcctttc gcctcaaaac ccagcaatcc tacgacgcca ttcaaaataa
    21241 agataaggcc aatagagaag gcatagtagt gccagtcacg acgaattttt acaggcaaac
    21301 gcataacgac tccgacgtat taacagcaac aaaaacgtat ttttgcatac ttctggcgag
    21361 cgagtctgtg ggggatacgg aatttcttaa atgttaattg attttgataa aagtgatcgt
    21421 tttgtgacaa ctaacaaaaa tttacgcgat ggatacattc catatgtgaa attaccatga
    21481 ttctgatatt gacaaacaca atgacctgtc agacttcaca gtaagccgat ggcataacgc
    21541 cagatcgtag ccgatcatcc tggaggtctt tatggctgat ttcactctct caaaatcgct
    21601 gttcagcggg aagcatcgag aaacctcctc tacgcccgga aatattgctt acgccatatt
    21661 tgtactgttt tgcttctggg ccggagcgca actcttaaac ctgctggttc atgcgccggg
    21721 tatctatgag catctgatgc aggtacagga tacaggtcga ccacgggtag agattgggct
    21781 gggcgtcggg acgatttttg gcctggtgcc cttcctcacg ggctgcctca tttttgccgt
    21841 tatcgccgcg tttttacgct ggcgtcaccg tcaccaataa accttagcgc gctggagaaa
    21901 atatcccagc gcgaaattta tcgccccata caccgcgccc gccgctcatc aactcgttta
    21961 gcaaaccagg cggtcgtcag cttacgcgtg atcttcggac tttccagttg aataccgggc
    22021 aacatttccc gcgcaagcgt cttgcccgtt ttggcctcgg ccagcttata gactttcttg
    22081 tagagcgccg ttttttcaaa cgccaggtta tcgcctttct ccagttggct gcgaatttca
    22141 cgctcactca ttcccaactg ccctgccagt ttgcgcaccg ctaactctgt tttgcccggt
    22201 tccttgctgt tataacgaat cagatcgcca tccagcgcca gttttacccc actggcttta
    22261 ctgacggcat tctggaacgc agcgttacgg ctggcgtacc atcccgcgtt gaagtcggcg
    22321 aagcggaaaa caggcgcgct gtagttcgcc gggtaattca gcaaatggta ggttccaaac
    22381 cacaatccgc cacggcgcgt aaagacctcc tgacgtaccg tacccgccat attccacgga
    22441 taacctttcg cgtgctgttc ggcaaaggca atgctgacct gcatcgggcc gcccgtatgc
    22501 accgggttat atgagccaaa tagcgtctgc cccataggga ccatattgat aaagtcgtca
    22561 aaaatagcgc taagctgttt ttcggttttt accgtgtcca ggcgttcgct atagctcttg
    22621 ccgttggggg agttaatttt cagcgcggtg tgcaccagaa acagcggaat gtgtagtcgt
    22681 tcagcgcggc gatcaatctc ctgccaggcg attttactta gccccggcac gacaggatcc
    22741 gcctgataac cggactcctg ctgggcgaca gccagcaccg aacagatatt ttctaccgtc
    22801 ggcgccagcc cctggctctt aaacgttgtc gcgatatctt tcgcccaggc ctctctgtct
    22861 ttgacactgg ccggcatttt ctgacgtact acgcttgcca cgtcgacagg cttctcgccc
    22921 ttgctcaccg gctgcccgga ttgactacta cagccagcca atatggcgac cgccagaaaa
    22981 ggcagaggat aaagacggga cgccgccgac ataacgtttc cttctgttag ctaaaagagt
    23041 gggtcacttc ctgaactggc tgaccatcca actggcgttc aaagctacgt aaacgtttat
    23101 aaatagacat cagctccacc agagtcgtcc aggagttaat caaatactgg aacgaaccgc
    23161 gcacctgacc aaacacgttg gtgatttgcg tcatcagccc cagcgtaatc gtaccggcaa
    23221 caatggaagg aaacagcagg aacaaaccga aaacgttatc gacctgcaaa tagagaatgc
    23281 gcgcgatgtt gaaatacata tagtgaaagt agagacggaa gtagttatgg cgcaccgcgc
    23341 taaacagttc acggacggtg ggcggcgtgg cgcggctggc gtcatcttca ccgtagacca
    23401 gctctttacg ataagctgcc tccactcgct gatttttaaa ttccagcccc gacaatttga
    23461 tcccgacgac cgccagcagg cccgtcccca ttaatgacca gactatggcg gcaatgacca
    23521 ggccgtaagg gatatgtcct acgatgggta aattcggcac atgcgctgac agggtgacca
    23581 acaccggcag aaaggcgata agcgtcatga tggcattgat aaaactcacg cccatgttct
    23641 ccagtgtaga ggcaaaacgc atggtatctt cctgcacacg ctgggcggcc ccttcgatat
    23701 ggcgcaggta ctgccagtgc gccatatagt gctcattcat tgcggtacgc cagcgaaata
    23761 catagtggct gacaaagaag ttgttcagca cgccgatcac cacggcgata agcgcaatac
    23821 cgagaaacac ccccacttca tgataaaatt gaccaagagt gaccttgtgc ggcgagttga
    23881 gcgccgtttg aatcaaatca tagaatggcg cgtaccaggc gttaaccgcg acgccaacct
    23941 ccaccaaaaa ccaggtgaca aaaataatga gcgaggtgcc aagtatcgac cagtactgcc
    24001 agcggtgcgg gctatagatg aaccagaacg ttgcaaataa tcccacgcaa atcaggtaat
    24061 aagcataaaa aatcagatag tccagcaacc agaagcgcgc tgcgctgata ggcacttcat
    24121 cggatgcccc tacaagtcgc gccacccaat ctcctcctcc cgcctgccag aaaatgacag
    24181 cgatcagcgc ccaaacaaac gccgacatga aaaacggccc tggctttggg aaaaaagatt
    24241 taaacatcat gctctcctgc taacttctta tctttattac ggctgctgtg acggcggcaa
    24301 tagcacgcca tgcccacggc taaaccaggc attgtgacct acgttgtgac gcttagttcg
    24361 catttctgct caacagaatt gtttcgacga gtttcatact cagcaggcac gctgacgcta
    24421 tcaggttatc acaagcgctt tatcacaaaa gtaaacattc tccatcacga aaacccgccg
    24481 ttacgttttt tcacccactt ttttctcttt aacgttttgc aatgtgccgc cgggtagtat
    24541 aaatacgcat aaccaccgtt atttcactta tggacatcac cgttgaaacg tagtctgctt
    24601 tttactgcca tgctgtttgc ggcatcactt acttctgtcc aggcggctca gccgattgcc
    24661 gatccggttt ttgcctctga tatcgttgat cgttatgccg agcatatctt ttatggtagc
    24721 ggcgccacgg gcatggcgct ggtggtgatc gacggcaatc aacgcgtgtt tcgtagtttc
    24781 ggtgacacca gaccgggcaa taatgttcgt ccacagcttg actcggtcat tcgtatcgct
    24841 tctctcacca agctcatgac cagtgaaatg ttggtaaaat tgctcgatca gggaacggta
    24901 aaattaaacg atccgctcag caaatatgcg cctcccggcg cgcatgtccc gacgtatcaa
    24961 ggcacgccga ttacgttggt caacttagcg acccacacca gcgcgcttcc gcgagaacag
    25021 cccggcggcg cggcgcatcg tccggtattt gtctggccaa cccgcgaaca acgctggaac
    25081 tggctctcca cagcaacgtt aaaagtcgcg cccggttcac aggcggccta ttccaatctg
    25141 gcgttcgacc tgttagccga cgcgctggcg accgcctccg gcaaacctta tacgcaactg
    25201 tttgaagaaa agattacccg cccgctggga atgaaagaca ccacgtttac cccctctccc
    25261 gatcagtgta agcgtctgat ggtggcagag aaaggcgcaa gcccctgtaa taatacgctg
    25321 gctgccattg gcagcggcgg agtctattct acgccaggag atatgatgcg ctggatgcaa
    25381 cagtatctgt cgtcagattt ctatcaccgt agccatcagg ccgatcgtat gcaaacgttg
    25441 atttatcagc gcgcacagtt aaagaaaatc atcgggatgg acgtaccggg taaagccgac
    25501 gcgctcggtc tgggctgggt ctatatggcg ccaaaagacg gacgtcctgg cattatccag
    25561 aaaacgggag gcggcggcgg ttttattacc tatatggcga tgatcccaca atataatatt
    25621 ggcgcttttg tggtcgtaac ccgttccccc ctcacccgtt ttaccaatat gagcgacggg
    25681 attaacgatt tggttactga gctaagcggc aataaaccga ttgctattcc tgcatcctga
    25741 gtcgtcgcgc ctcgcgctat atcagacgag gcgcgacatt tttgttaata ttcggagggc
    25801 aaacggttaa tactgatcaa tttgccttta ttcatttcaa tgtaattacc cttacgcagg
    25861 gccgcgagaa cttccgccac caccgatcgc gatacgcgcg ttcgttgatg tatataattc
    25921 ataacaccaa tacgtgagcg aagttcttca tcccactcaa tcattgtcat taacgtcgca
    25981 cgaatctggt cgtaagaatt attaccaatg agctgcttgt cacgaagctc cagtacctga
    26041 cttttccata ctatccaaca gaaggcttca cgccacagtt ggttctgctc aatgatggcg
    26101 agagtttgtg atgatgagag gcgataaccg atgcaaccgc tctccgcaat taatttatat
    26161 tgtgcctctt ttttcgccac gccatcggct aagccaaaaa taaaaggggc ctgcacaata
    26221 ccaataagaa ctttatcacc ccgaactaac gaaacaaccc cctctaaaat aacaaaggta
    26281 tgggtattac tttcatcagg tgaacagata atctctttat cgttaacaaa ctcgaaacgc
    26341 gtaccatgct tagaaaggca tttatcgagt ctgttgaatt cctgtagtgg cttgtttaaa
    26401 gataacatat gcattccttg caataatgcc cgtcaagtcc ttgacgggca tttttcagtt
    26461 taaattactt ttatttctcc tgagagaaaa tgattaccag gtatatttaa caccaacgtt
    26521 tgcagaccag tcttgatcaa catcaccgcc gccgaggtag ttagcatcgg tgtaggcgct
    26581 gaagttcttc gtgaagctga actgagtacc cagaccaaca cgtaccgcaa aaccttctac
    26641 gccgttgtcg atagagtcgc cgtttacgtc agcatcgttg ttggagtcgt cgtaaacgta
    26701 agccagtttg aagtacgggg tcagcgcctg atcttcgctg taagtgaagg tataacctgc
    26761 atctacaccg agttcataac gcatgctgtc gtaagactga ccgtcaactt tcatgtcgtt
    26821 gctcagctgg tagtcgtcgc cggactggaa cagaccggat acgctgccgt aaggcgttac
    26881 gtagcctgca tcacccagct tcagatcata acccagtttc aagccgaagc cccaggcgtc
    26941 agaagaggtg ttgccgtcaa cgtaagtacc gtcgctcatg ttagcagaca aatcgttgtt
    27001 gaagtgagag tagcttaagt taccgtcaac aaagatgttg tttgcgaaac gagcggaaga
    27061 gtagatgtag gcagactggc tgtcctgatc cacctgaccg gtacgatcgc tcagatcgcc
    27121 tttcgcgaag cctgctgccg caccaacgat ccacttagcg ttgttaccgt caactttggt
    27181 atcaacaccg accatgatgc cattaacatc ctgatcgtag ttaatggtgc cgttgtcgcc
    27241 gttgaagtta ccgccgaagt agcttaccca tgcgccgccg ttatccgcca ggccatgacg
    27301 agcgttggtc agacgagtac caacggtgtc ttgttccagg ttccagatat tggtgttcgc
    27361 agaaggaatg ctcagcgcca tgttagcgta gtcggtcagt tccatctgtt ccagcacgac
    27421 agtgttgcct tcctgcttag cctgataggt gtaagcaccc aggtcagctt tgtttgctgc
    27481 agagaaggta gcgtcggtgt ttatgtcatt gacataaatc agctcgttac ctttgtaatc
    27541 cgcaacagaa ccggcaccag tagcgttgtc gatgcgcact ttataattac cagtggccgc
    27601 tacaacgttg tcagtggtgc tacttgcatc agcctcgtca ccattgttga tatcgccgtt
    27661 accgttgata gtcagatgac catcagagtt catcgcgaca acgccgtaac cgtagttagc
    27721 ctgagtggta tcccaggtac ggtcgttcac caaatcggca tttagggtat agtcattgct
    27781 atgaatgttg aacacaccag cataaacatt gccattatta tccgcaacgt tactgctagt
    27841 cagttctaac gtatcagtat caatgacgct atctgcgttt gtattgttgg tttgaatatc
    27901 taacatacca ccgtgagtta cggtaatagt attagcatac agtgcatcat cactccatgc
    27961 actgctgaca tcatcagcca aagtaactgt actgaaagta tcaacggtca ggtgatcagt
    28021 atcaacgtag ccaccttccc cgatgttcat agctgaacca ccgtttagag taatggtatc
    28081 agcggttaaa ttggagccat tagcgacatc aacctgagag ccgctattta ctgctaaggt
    28141 atctattaca gatgtttttg tggtatccca ctcagatcca ttattcaagc tgacgtcaaa
    28201 gataccgctc tggaaggaag cagcactatt aacacgtccc caggcatcat aattagtcga
    28261 gtctggatct aagctattgg catcaacatc atagaattgc actggatcca ttgactgtga
    28321 atcattaacc gccgcaccaa cccatttagt gttattcagg gtcaatgtca ggtgatcaac
    28381 gttttgatca tcatctgccc aaccaccatt cgtatagaca gtagtggaat catcgactaa
    28441 acggccatta gaatagaaat tataattcca ggagctctca aggacgacat cccccagtaa
    28501 ctgcgagtcg gtaaacgtaa cgttgtttac catacggtaa tttgaataag gatcgtcaac
    28561 aaaagctaaa gcaacatcat ctttattcca accattgcca ttataatcgc ttggttcact
    28621 tgaattgcca aaatggcctt gttcctcatc ttcggaccag gagcctgaag ttacagttga
    28681 attcgctacg ttaatagtgt tatcccactg atgtgcttcg gttgtatatg ttgaattgcc
    28741 aagatcattt tggtaaagag caataccagc cacatgagaa ttgttagtaa tattaatatt
    28801 actttcaaca tcaagggtta tagcagtgcc taaaccagca gtaaccaatt tgtcataatc
    28861 ggttttgact gtttttccat cagaatcgag ataggtatca gtgaagtaaa acgcctcaaa
    28921 gtcatcatcg attgtagaat tagaaatgtt tagattaaaa gtatcatcat caacccaatc
    28981 atgggtcgta taatcactac cgttagtcca aacatattga ccgtagccca tctggtaaga
    29041 agtaatcata ccatgaatgg ttgagttggt aacatccaat gtattcgcag tatcattggc
    29101 gtaatcatga ttcagataat aagttgaaat aacgccattt acagtgtcac cagtaaattt
    29161 tgtatcaaaa tagccgctat cactagctgg ggtgttgtag acataaccac cataagttag
    29221 atagtcatgg tcgttggtat catcccagcc aaaaacagtg gccgcatcgt catggtaccc
    29281 aaaagtatcg tatgtagtag cattcgcctg agaagtgatt gccagagtgc aagccaatgc
    29341 taattgtgag actacaagtt tctttttcca ggagtgcatt tgtcatccct cctcagggac
    29401 gtaatatagt tgatccatca attatcaatg cataaaaaca tatagatgtt tagcaaggag
    29461 gattatgcgg cgtcattgct aaaaggttca attattcttt atcctcagtc cggattcgga
    29521 catgaattaa aaaggcgtaa taaaaggaaa gttgataatt aaaaagcgtt ctttttcatg
    29581 accttgcaag aaaataaaaa aacaaaatac atataagata aatatgaatt aaagaaaaac
    29641 aaaataaata tgaataatgt caaaatccac atttacttaa atgacgatga aataaa
//
LOCUS       DAJVKX010000046        29516 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000046 DAJVKX010000000
VERSION     DAJVKX010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29516
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.046"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..299)
                     /gene="tuf"
                     /locus_tag="OPY25_002094"
     CDS             complement(<1..299)
                     /gene="tuf"
                     /locus_tag="OPY25_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCS0927707.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQM"
     gene            complement(371..2485)
                     /gene="fusA"
                     /locus_tag="OPY25_002095"
     CDS             complement(371..2485)
                     /gene="fusA"
                     /locus_tag="OPY25_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCS0927708.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVGQIKT
                     RLGANPVPLQLAIGAEEGFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMQDLANEW
                     HQNLIESAAEASEELMEKYLGGEELTEEEIKQALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKTARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPENPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYREAIRAKVTDIEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKSGPL
                     AGYPVVDLGVRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDDAPNNVAQAVIEARGK"
     gene            complement(2582..3052)
                     /gene="rpsG"
                     /locus_tag="OPY25_002096"
     CDS             complement(2582..3052)
                     /gene="rpsG"
                     /locus_tag="OPY25_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCS0927709.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAADNKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="OPY25_002097"
     CDS             complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="OPY25_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCS0927710.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="OPY25_002098"
     CDS             complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="OPY25_002098"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HCS0927711.1"
                     /translation="MLHTLPHCASGVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFL
                     ESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTEFVRLTVKYANQMAW"
     gene            complement(3943..4299)
                     /gene="tusC"
                     /locus_tag="OPY25_002099"
     CDS             complement(3943..4299)
                     /gene="tusC"
                     /locus_tag="OPY25_002099"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HCS0927712.1"
                     /translation="MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGV
                     FQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLENVNFVVNATPLEP
                     VALRRELGNYDVILRF"
     gene            complement(4299..4685)
                     /gene="tusD"
                     /locus_tag="OPY25_002100"
     CDS             complement(4299..4685)
                     /gene="tusD"
                     /locus_tag="OPY25_002100"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HCS0927713.1"
                     /translation="MRYAIMVTGPAYGTQQASSALQFAHALLNEGHELASVFFYREGV
                     YNANLLTSPASDEYDLVRVWQKLNTQHGVALNICVAAALRRGIIDETEAGRLELPSAN
                     LQPGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4685..5407)
                     /locus_tag="OPY25_002101"
     CDS             complement(4685..5407)
                     /locus_tag="OPY25_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0927714.1"
                     /translation="MSRSLLTNETSELDLLDQRPFEQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMNTFIPPETPEVGSAVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5684..6502)
                     /gene="fkpA"
                     /locus_tag="OPY25_002102"
     CDS             complement(5684..6502)
                     /gene="fkpA"
                     /locus_tag="OPY25_002102"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCS0927715.1"
                     /translation="MKSLFKATLLATTMAVAMHVPITFAADAAKPAATADSKAAFKND
                     DQKAAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QTFEARVKSAAQAKMEKDAADNEAKGKTFRDAFAKEKGVKTSSTGLLYKVEKEGTGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKSGKIKLV
                     IPPALAYGKTGVPGIPANSTLVFDVELLDIKPAPKADAKPADAADAKAADAAKK"
     gene            6722..6940
                     /locus_tag="OPY25_002103"
     CDS             6722..6940
                     /locus_tag="OPY25_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HCS0927716.1"
                     /translation="MQDITMEARLAELESRLAFQEITIEELNLTVTAHEMEMAKLRNH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(7127..7717)
                     /gene="slyD"
                     /locus_tag="OPY25_002104"
     CDS             complement(7127..7717)
                     /gene="slyD"
                     /locus_tag="OPY25_002104"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCS0927717.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITEVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHGEDGCCSGHGHDHGHEHGGEGCCGGGGKGSCGCH"
     gene            complement(7812..8012)
                     /locus_tag="OPY25_002105"
     CDS             complement(7812..8012)
                     /locus_tag="OPY25_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HCS0927718.1"
                     /translation="MAIRKRFIAGAKCPACQAQDTMAMWRENNVDIVECVKCGHQMRE
                     ADKDVREHVRKEEQVIGIFHPD"
     gene            complement(8022..9827)
                     /gene="kefB"
                     /locus_tag="OPY25_002106"
     CDS             complement(8022..9827)
                     /gene="kefB"
                     /locus_tag="OPY25_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HCS0927719.1"
                     /translation="MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVL
                     AGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFT
                     AATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFI
                     SVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGG
                     EFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDE
                     KPWVEDDKPQVVVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGD
                     ATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELL
                     QAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELIPEHSDM
                     VQISRAREARRELEEIFQREMQQERRQLDGWDEFE"
     gene            complement(9827..10378)
                     /gene="kefG"
                     /locus_tag="OPY25_002107"
     CDS             complement(9827..10378)
                     /gene="kefG"
                     /locus_tag="OPY25_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HCS0927720.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARY
                     PDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSP
                     QTLASHAKAYGEWLANPVSAGGY"
     gene            10644..12551
                     /locus_tag="OPY25_002108"
     CDS             10644..12551
                     /locus_tag="OPY25_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0927721.1"
                     /translation="MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPAIEYVIDGDREYRHLEAQLNDAN
                     ERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIH
                     IEQQTLFEYTGNYSAFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSAGYGDRIILESIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADE
                     SPLQHMARLAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLIRSTTDDLYLVHDKKVEPF
                     DGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQPLRKEIT
                     RLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEA
                     QEQLEQMMQND"
     gene            12696..12917
                     /locus_tag="OPY25_002109"
     CDS             12696..12917
                     /locus_tag="OPY25_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0927722.1"
                     /translation="MNLSITDDITFRKLTIFMMLVEKGNIARTAETLHTLEENVRCPL
                     FVHKGLFGTRPDIKVTVAVGSTGTEACVM"
     gene            complement(12919..13230)
                     /locus_tag="OPY25_002110"
     CDS             complement(12919..13230)
                     /locus_tag="OPY25_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HCS0927723.1"
                     /translation="MSKTLLQIHFNFSGPFGEEMTQQLVGLAESINEEPGFIWKIWTE
                     SEKNQQAGGIYLFESEETAQAYIKKHTARLKNLGVDEVTFTLFGVNDALTKINHGNLC
                     R"
     gene            13428..14415
                     /locus_tag="OPY25_002111"
                     /pseudo
     CDS             13428..14415
                     /locus_tag="OPY25_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462365.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
     gene            14412..14630
                     /locus_tag="OPY25_002112"
     CDS             14412..14630
                     /locus_tag="OPY25_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462366.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HCS0927724.1"
                     /translation="MIIPWQGLAPDTLDNLIESFVLREGTDYGEHERSLEQKVADVKR
                     QLQSGEAVLVWSELHETVNIMPKKQFRE"
     gene            14682..15551
                     /locus_tag="OPY25_002113"
     CDS             14682..15551
                     /locus_tag="OPY25_002113"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HCS0927725.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFSLLEHTFIEYGQTGKGQSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHDVARHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMDDYINYITPQFSRTHINFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(15647..16051)
                     /locus_tag="OPY25_002114"
     CDS             complement(15647..16051)
                     /locus_tag="OPY25_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HCS0927726.1"
                     /translation="MQARVKWVEGLTFLGESSSGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQNVTNCEVKLTSERREDAPRLFTHINLHFIVTGGDLKEAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVIAA"
     gene            16359..16991
                     /gene="crp"
                     /locus_tag="OPY25_002115"
     CDS             16359..16991
                     /gene="crp"
                     /locus_tag="OPY25_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HCS0927727.1"
                     /translation="MVLGKPQTDPALEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSSQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            17040..19127
                     /locus_tag="OPY25_002116"
                     /pseudo
     CDS             17040..19127
                     /locus_tag="OPY25_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462370.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
     gene            complement(19170..20387)
                     /locus_tag="OPY25_002117"
     CDS             complement(19170..20387)
                     /locus_tag="OPY25_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HCS0927728.1"
                     /translation="MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEY
                     IDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNVFTNEPALCLGRKLIDATFAERV
                     LFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDK
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAF
                     HVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSD
                     IRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADINEG
                     MQRFAQAVGKVVA"
     gene            complement(20473..21036)
                     /gene="pabA"
                     /locus_tag="OPY25_002118"
     CDS             complement(20473..21036)
                     /gene="pabA"
                     /locus_tag="OPY25_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HCS0927729.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNP
                     QKIVISPGPCTPNDAGISLAVIRHYAGRIPMLGVCLGHQAMAQAFGASVVRAAKVMHG
                     KTSPVTHNGQGVFRGLPSPLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREW
                     DLEGVQFHPESILSEQGHALLENFLRR"
     gene            complement(21068..21670)
                     /locus_tag="OPY25_002119"
     CDS             complement(21068..21670)
                     /locus_tag="OPY25_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HCS0927730.1"
                     /translation="MSDKFGEGRDPYLYPGLNVMRNRLGIHQAQRLAQAAYEMTALRA
                     ATIELGPLVRGLPHLCAIHRQLYQDIFDWAGQLREVDIYQGDTRFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLTHEKFVERLAHYYCEINVLHPFRLGSGLAQRIFFEQLALHAGYAL
                     SWQGIAVETWNQANQSGAMGDLSALRAIFQKAISEARETE"
     gene            complement(21660..21827)
                     /locus_tag="OPY25_002120"
     CDS             complement(21660..21827)
                     /locus_tag="OPY25_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HCS0927731.1"
                     /translation="MKKLTDKQKSRFWEQRRNVNFQQSRRLEGIEIPLVTLTADEALA
                     RLDELRRHYER"
     gene            complement(21936..22508)
                     /gene="ppiA"
                     /locus_tag="OPY25_002121"
                     /gene_synonym="rotA"
     CDS             complement(21936..22508)
                     /gene="ppiA"
                     /locus_tag="OPY25_002121"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HCS0927732.1"
                     /translation="MLKSTLAAVAAVFALSALSPVALAAKGDPHVLLTTSAGNIELEL
                     NSQKAPVSVKNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFNEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPTKPVVILSAKVLP"
     gene            22785..23966
                     /gene="tsgA"
                     /locus_tag="OPY25_002122"
     CDS             22785..23966
                     /gene="tsgA"
                     /locus_tag="OPY25_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HCS0927733.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFQLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFILMVLAVAGLMFSHSLALFSAA
                     MFVLGLVSGITMSIGTFLITQLYEGRQRGSRLLFTDSFFSMAGMIFPMVAAFLLARSI
                     EWYWVYACIGLVYLAIFILTFGCEFPALGKHAQHSQAPVVKEKWGIGVLFLAVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGALVSDFWMSYMFGMWAFSFILRFFDLQRILTV
                     LAGMAAILMYLFITGTQAHMPWFILTLGFFSSAIYTSIITLGSQQTKVASPKLVNFIL
                     TCGTIGTMLTFVVTGPIVAHSGPQAALLTANGLYAVVFVMCFALGFVSRHRQHSSPAA
                     H"
     gene            24283..26826
                     /gene="nirB"
                     /locus_tag="OPY25_002123"
     CDS             24283..26826
                     /gene="nirB"
                     /locus_tag="OPY25_002123"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HCS0927734.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDASLFDITVFCEEPRKAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGVKVLVGERAITINRQEKVIHSSAGRTVYY
                     DKLIMATGSYPWIPPIKGSETQDCFVYRTIEDLNAIEACARRSKRGAVVGGGLLGLEA
                     AGALKNLGVETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTQEIVQQGN
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLAVAQRGGIVINDTCQTSDPDI
                     YAIGECASWNNRVYGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEVYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPSHASSGKPAIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLTKHGKGYGCEVCKPTVGSLLASCWNEYILKPQHTPLQDTNDNFLANIQKDGTYS
                     VIPRSAGGEITPEGLVAVGRIAREFNLYTKITGSQRIGLFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGFGVELENRYKGIRTPHKMKFGVSGCT
                     RECAEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADLDRDTLIKYLDRFMMFY
                     IRTADKLTRTAPWLDNLEGGIEYLKSVIIDDKLGLNEHLEEEMARLRAAVVCEWTETV
                     NTPAAQVRFKHFINSDKRDPNVQVVPEREQHRPATPYERIPVTLVEENA"
     gene            26823..27149
                     /gene="nirD"
                     /locus_tag="OPY25_002124"
     CDS             26823..27149
                     /gene="nirD"
                     /locus_tag="OPY25_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HCS0927735.1"
                     /translation="MSQWQNICKIDDILPGTGVCALSGGEQVAIFRPYHSDQVFAISN
                     IDPFFEASVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYDARVKDG
                     VVQLCG"
     gene            27331..28140
                     /gene="nirC"
                     /locus_tag="OPY25_002125"
     CDS             27331..28140
                     /gene="nirC"
                     /locus_tag="OPY25_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HCS0927736.1"
                     /translation="MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTLGVKAGTISHGQMW
                     AILPQTWLGNLVGSVFVALLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALC
                     NWLVCLAIWMAIRTEGTAKFLAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYT
                     LSGIGHNLLWVTLGNTLSGVVFMGLGYWYATPKSERPVPQKTNQIKATANH"
     gene            28152..>29516
                     /gene="cobA"
                     /locus_tag="OPY25_002126"
     CDS             28152..>29516
                     /gene="cobA"
                     /locus_tag="OPY25_002126"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HCS0927737.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALT
                     FIPQFTVWVNEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSEAAESRRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQ
                     LRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTEHLFSEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQE
                     KLIAFGMEANMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVALRDK
                     LNWFS"
BASE COUNT         6929 a         8131 c         7639 g         6817 t
ORIGIN      
        1 tccatctgcg cagcaccggt gatcatgttt tttacatagt cggcgtgccc cgggcagtct
       61 acgtgtgcgt agtggcgggt cggggtatcg tattcaacgt gagaagtgtt gatggtgata
      121 ccacgcgctt tttcttccgg agcgttatcg atctggtcga atgcacgagc agcaccgccg
      181 taggttttag ccagtacggt ggtgattgca gcggtcaggg tagttttacc gtggtcaacg
      241 tggccgatgg tgccgacgtt aacgtgcggt tttgtacgtt caaatttttc tttagacacg
      301 gctatattcc ttactatagc gctctcccct tcaggagaga gcacgggatt ttggttttta
      361 accctgcggc ttatttacca cgggcttcga ttacggcctg agcaacgttg ttcggcgcat
      421 catcatactt caggaattcc atagtgtacg atgcgcgacc tttggtcaga gaacgcagct
      481 gagttgcata tccgaacatt tcagacagcg gtacttcagc gtggatctta acgcctgtaa
      541 cttcagattc ctgacctttg agcataccac gacggcggct aaggtcgccg ataacgtcac
      601 cggtattctc ttcaggtgtt tctacttcaa ccttcatgat cggctcaagc agaactggtt
      661 ttgctttctt aaagccttct ttaaaggcga tagacgcagc cagtttaaac gccagctcag
      721 aggagtcaac gtcatggtaa gaaccgaagt gcagacgcac accgagatca actaccggat
      781 aacccgccag cgggccagat ttcagctgct cctggatgcc tttatcaacg gccgggatgt
      841 actcgccagg aattacacca cctttgatgt cgttgatgaa ctcgtaacct ttcgggttag
      901 agcccggctc cagcgggtac atgtcgataa caacatgacc atactgaccg cgaccaccag
      961 actgtttcgc gtgtttacct tcgatgtcgg taactttcgc gcgaatcgct tcgcggtaag
     1021 caacctgagg tttacccacg ttcgcttcaa cgttgaattc acgcttcata cggtcaacga
     1081 tgatatctag gtgaagttca cccataccag cgatgatggt ctggttagat tcttcatcag
     1141 tccatacgcg gaacgacggg tcttctttcg ccagacggcc cagagccaga cccatttttt
     1201 cctggtcagc tttggttttc ggttctaccg cgatggagat taccggctca gggaattcca
     1261 tacgttccag aatgatcggg ttttccggat cacacagggt gtcaccggta gtcacgtctt
     1321 tcaggccgat agcagccgcg atgtcgcccg cgcgaacttc tttgatctct tcacgtttgt
     1381 tagcgtgcat ctgaacgata cgaccgaaac gctcacgtgc ggttttcacg gagttcagta
     1441 cggtatcacc agagttaacc acaccggagt acacacggaa gaaggtcagg ttacccacaa
     1501 acgggtcggt agcgattttg aacgccagcg cagagaacgg ctcgtcgtcg cttgcgtgac
     1561 gctcagccgg agtatcttta ccgtcgtcca gaataccgtt gatcgcaggt acgtctaccg
     1621 gggatggcag gtaatcaatt accgcatcca gcatcgcctg aacacctttg ttcttaaatg
     1681 cagaaccaca ggttaccagg atgatttcgt tgttcagaac gcgctgacgc agagcttgtt
     1741 tgatctcttc ttcagtcagt tcttcaccac ccaggtattt ttccatcagc tcttcagaag
     1801 cttctgcggc ggactcgatc aggttctggt gccattcgtt agccaggtcc tgcatgtcag
     1861 ccgggatatc ttcgtattcg aaggtaacgc cctggtcggc atcgttccag ttgatggctt
     1921 tcattttcac caggtcaaca acgccggtga aaccttcttc agcaccaatt gccagctgca
     1981 gcggaaccgg gttcgcgccc agacgggttt tgatctgacc aacaactttc aggaagttcg
     2041 cgcccatgcg gtccattttg ttaacgaacg caatgcgcgg aactttgtat ttgtttgcct
     2101 gacgccatac ggtttcagac tgcggctgaa caccaccaac tgcgcagtaa accattaccg
     2161 caccatcgag aacacgcatg gaacgttcta cttcgatagt gaagtcaacg tgccccgggg
     2221 tgtcgatgat gttgatgcga tgcggttcat actgcttagc cataccagac cagaatgcag
     2281 tagtcgctgc ggaggtgata gtaataccac gctcctgctc ctgctccatc cagtccatgg
     2341 tagctgcgcc gtcatgaact tcaccgattt tgtggtttac accggtgtag aacagaatac
     2401 gttcggtagt agtggtttta ccggcgtcga tgtgcgcact gataccgata ttacggtagc
     2461 gtgcgatggg tgttgtacga gccatttgat tcctcgttga tatctttagg cgttcagtta
     2521 agttatccaa aacgggcgac ttacctgaag cgcccgcctg gtgactatga ctccgaaggg
     2581 attaccaacg gtagtgtgcg aacgccttgt tggcttctgc catacggtga acgtcttcac
     2641 gtttcttaac tgcagtacct ttgttgtctg cagcgtcaga aagttcgttc gccaggcgca
     2701 gagccatgga tttatcaccg cgtttacgag cagcttctac gatccaacgc attgccagag
     2761 cattacgacg gaccggacgg acttcaactg gtacctgata agtagaacca cctacacggc
     2821 gggatttaac ttctacagtc gggcgaacgt tttcgagagc gacttcgaaa gcttccagtt
     2881 cagatttacc agaacgctga gccagggtct ccagcgcgct gtatacgatt gattctgcag
     2941 tagatttttt accatctacc atcaggatat tgacaaattt agccagcagt tctgatccga
     3001 acttcggatc cggcagaatt ttacgctgac caatgacgcg acgacgtggc atggaaatac
     3061 tccgttgtta attcaggatt gtccaaaact ctacgagttt agtttgacat taatttaaaa
     3121 cgtttggcct tacttaacgg agaaccatta agccttagga cgcttcacgc cgtacttaga
     3181 acgagcttgc ttacggtctt taacgccgga gcagtcaagc gcgccacgaa cggtgtggta
     3241 acgaacaccc gggaggtctt taacacgacc gccacggatc aggatcacgg agtgctcctg
     3301 caggttgtga ccttcaccac cgatgtagga agtcacttca aaaccgttag tcagacgaac
     3361 acggcaaact ttacgcagtg cggagttcgg ttttttagga gtggtagtat atacacgagt
     3421 acatacgcca cgtttttgcg ggcatgcttc cagcgcaggc acgttgcttt tcgcaacttt
     3481 gcgagcacgt ggtttgcgta ccagctggtt aactgttgcc attaaatagc tcctggtttt
     3541 agcttttgct tcgtaaacac gtaataaaac gccctcacac aatatgagga cgccgaattt
     3601 tagggcggtg tcgaaaaggt gtcaagaaat atacaacgat cccgccatca ccaggccatc
     3661 tggttggcat acttaaccgt gagtctgaca aactcagtat agtcaaccct gacgacactg
     3721 tctgaaattt gaccacccag gccgcgagcg tcaatgtctt ctttcaaggc atagaccgtt
     3781 atgggggcat cgcgcagact ttcaaggaag cggttacctt caatcgcgac ggtaacgcca
     3841 tcctggagca gcaaaagcgc atcgccctct tttagcaggc gcagcaaagc gggaaaatca
     3901 acgcccgaag cgcaatgagg taaggtatgc agcataaacg cctcagaatc tcaggatgac
     3961 atcatagttg ccaagctcgc ggcgtaacgc cacgggttcc agcggcgtgg cgtttaccac
     4021 aaaattaacg ttttccagac cacgctcgcg cagcgatgcc gcgcagatcc agcattgatc
     4081 aatatcgtac aaatcaaaga gcttgaaagt agcaatatag tcacgcgcca gcacagcgtc
     4141 tggtttttgc cccggtaata actgaaagac gccgtcgctg ataaaaaaga cgcccagcgc
     4201 ttccgttagc gctgacgtcg ccagcagcgc atccagtcct tcacggcctg aggcgctacc
     4261 gtgcggcgcg gtggaaaaga caaatgcaat acgtttcatt aaaactgcac cacccgatcg
     4321 caggtgagag aagcctccgc cagcgcgccc agtccgctta gcgtaaagcc cggctgaaga
     4381 ttggcggacg gcaactccag tctgccggct tcagtttcat caataatacc gcgacgaagc
     4441 gccgccgcga cacagatgtt cagcgctacg ccatgctgcg tattcaattt ctgccagacg
     4501 cgtaccagat catattcatc gctcgccggc gaggtcagga gattggcgtt atagacacct
     4561 tcccgataga aaaagacgct ggctaactca tgcccctcat tgagcagcgc gtgggcgaac
     4621 tgcaatgcgc tgctggcctg ctgggtgcca tatgcaggcc cggtgaccat aatggcataa
     4681 cgcattattt atcctgcccc tgaaaatcgc cgcttttgaa ctggcgaata tagaggtaaa
     4741 ccgtgtgttt tgagatattc agacgatcgg ctacctggtt aatggcgtct ttaatatcga
     4801 aaatgccttt ttcgtacaag ttaaggacga tctgacgatt tttcgcattg ttagagacat
     4861 tacgatcggc attcacttct tcgatcgtga actccagcgt ctgggtgact aaatcttcga
     4921 ctgaggaggc aaaattaacc gctgagccga cttccggcgt ttccggcgga ataaaggtat
     4981 tcataatctg tgaaaatggc acatcaagat tcatgttgat gcacagtaga ccaatgacgc
     5041 gctgctcgcg gttgcgaatg gcaatcgtca acgacttcat caagacaccg cttttcgcgc
     5101 gcgtaaaata gcatttcgac acgctactgt ccgcccctgt catgtcgtgc aacatgcgca
     5161 acgccaggtc ggtaatcggc gagccaattt tacggcccgt atgttcgcca ttggcaatac
     5221 gaatggctga acattttaga tcctgcaaag agtgcaatac gatttcacaa tgggaaccta
     5281 taagcatcgc taacccgtcc actaccgctt cgtaggattt cagaatatcg aagtcggttt
     5341 gctcgaaggg acgctgatcc agcaaatcaa gttcactggt ttcgttggtt aaaagcgacc
     5401 tggacatgaa aaaaaacact ccttttcagg agcctgtcgt tatgttttca gggcaggctc
     5461 attatttacg cggatgatta aattaataca gtgagggttc atctttccag tactaatttg
     5521 ctcgtctatt tcagactacg tgtgcgttgg cggtcattca gcctacggtc tcgcccttaa
     5581 cgaccagcgc aagcgccgtt atccgcaaat caaattatgg tgagtaatat atccggcctg
     5641 aataaaaaaa accgccgcta ttacaagcgg cggctctcag tttttatttt ttagcagcat
     5701 ctgcggcttt agcgtcagcc gcatcggcag gtttagcatc cgctttcggc gctggtttga
     5761 tatccagcag ctctacgtcg aataccaggg tggagttcgc agggataccc ggaacgcccg
     5821 ttttaccgta ggccagcgcc ggtgggataa ccagcttgat cttgccgctt ttcttaatat
     5881 ttttcaggcc ttcagtccag ccagggataa cgccgtccag acggaaggag agcggttcgc
     5941 cgcgcgtgta agagttatca aactctttac cgtcgatcag cgtacctttg tagttcacca
     6001 caacggtatc gctatctttc ggcgcctcgc ctgtgccttc tttctctact ttgtaaagca
     6061 gaccggtaga ggaggttttc acgcctttct ctttagcaaa agcgtcacgg aacgttttac
     6121 cttttgcttc gttatcggca gcgtcttttt ccatcttcgc ctgagcagcg ctcttcacac
     6181 gtgcttcaaa cgtctgcagc gtttgctcaa tttcctgatc ggacagtttg ctcttatcgg
     6241 caaaggcatc ctgaacgccg gcaatcaact gatctttatc cagtttgatg cccaactttt
     6301 cctgctcttt aagcgaattt tccatgtaac gacccagcga ggcgcccagc gcataagccg
     6361 ctttttgatc gtcgttttta aatgctgctt tgctatcagc ggtagctgcc ggtttcgccg
     6421 catcagcagc aaaagtgatc ggtacgtgca tagcaacggc catcgtcgtt gccagcagcg
     6481 tggctttaaa cagtgatttc atccatatct ccagggccgg ggcatctcgc cccatgttaa
     6541 cttacgtaag aagcgtacta taaatcgttg cagaacaaat caacatacga acacgcccta
     6601 ttatcacttc ttttcagact ctttttgttt aaattagttt cgtagggcgc gtaatggttg
     6661 ctgtgaaagc cggtaaagtt aagtagaatc cgccgacgga gacaacataa agaggtacat
     6721 catgcaggat atcacgatgg aagctcgtct ggctgaactg gaaagccgtc tggcgttcca
     6781 ggagattacc atagaagaac taaacctgac ggtaaccgca catgaaatgg agatggcgaa
     6841 gctgcgcaat catctgcgtt tgctcacgga aaagttaaaa gccagtcagc cgtcaaatat
     6901 cgcctctcag gcagaagaaa cgccgccgcc gcattattga gacgaaaaaa agcggggata
     6961 cccgcttttt ttgtgcccga tgatttatcg aaccaatgat aataacctaa ggatttcgag
     7021 tcacagcaaa gcggcaagct tgaaaattcc ccgggaacat agataactat gtgaccgggg
     7081 tttgaaagcg tagccaacac cgcggtggct tgaaagacga cggggattaa tggcagccgc
     7141 agctgccttt accaccaccg ccgcagcagc cttcgccgcc gtgctcgtga ccatggtcat
     7201 gaccatgacc gctacagcag ccgtcttcac cgtgatcgtg gtggtgatcg tgcgcgccgt
     7261 gaacatgacc gtgagccagt tcttcttcag tcgcttcacg aatcgcaaca acttcgacgt
     7321 taaatttcag attctggccc gccagcatgt ggttaccatc aaccacaacg tgatcgtctt
     7381 ccacttcggt aatctctacc ggtaccgggc cctggtcggt ttccgccagg aaacgcatcc
     7441 ctacctgcag ttcatcaacg cccataaaga cgtctttagg cacacgctgc accagatttt
     7501 cgtcatactg gccgtaagcg tcgttcgcgc caacagcgac atcaaatttg tcgccaactt
     7561 catggccttc cagcgcggtt tccagaccag agatcaggga gccgtgaccg tgcaggtaat
     7621 ccagcggcgc actcaccgga gactcatcaa ccaacacacc gtcttctgta cgtacctgat
     7681 aggccaggct gaccaccagg tcttttgcta ctttcatgat atctcctgag catgggaaga
     7741 atagtggcgc agattgtagc ggaattctgc agccgtgtac cccttagctt aaaaaaacct
     7801 gcggcatatc gctagtccgg atgaaaaatc ccgatcactt gctcttcttt gcgaacatgc
     7861 tcgcgaacgt ctttatccgc ttcccgcatt tgatgcccgc acttaacgca ttcaacaata
     7921 tcgacattat tttcacgcca catcgccatt gtatcctgcg cctgacaggc cggacatttc
     7981 gcgcctgcaa taaaacgttt acggattgcc attgttcacc tctactcaaa ttcatcccag
     8041 ccatccaact ggcgccgttc ctgttgcatt tcgcgctgaa aaatctcctc cagctcgcgt
     8101 cgggcctctc tggcgcgcga aatctgtacc atgtcgctat gctccgggat cagctcccgc
     8161 aacattcgca tatccagccg acgaaaatgc aactgcgcgc gttgcgcctg atgcggatgc
     8221 atacctaacg acaccagagt tttacgtccc agttccagcg cgctggaaaa cgtttcacgg
     8281 gaaaactgcg tgacgccagc ctgtaataac tcatgggcct ccacacgtcc acgcgctcgc
     8341 gcaagaatat gcagatgagg aaaatgctgc tgacacagcg ccaccagctt catcgtgtct
     8401 tccggttcat tacacgtgat gactatcgac tccgccgcct ccgcgcccgc agaacgcagc
     8461 agctcgactt gtgtagcgtc gccgtaatac actttataac catatttgcg catcagatta
     8521 acggcgccga tatcgcgttc cagcacggtg atacgcatct tattcgccat caataagcga
     8581 gcgatcacct gaccaaaacg gccaaagccg acgacaacca cctggggctt atcatcctca
     8641 acccacggct tttcatcatt ctcttccggg ccattaagac ggcgcgataa ccacttatca
     8701 atccctttca tcagtagcgg cgtggtcatc attgataatg tgacagtcac caataataac
     8761 gccatctgat cgccctgaaa caggcgctga gaagaggcgg tagaaaagag cacaaaagcg
     8821 aactcgcccc cctgactcag cacgctggca aactgcatcc gttcagaact tcttattcca
     8881 tatagccgcg ccagcagata cagcgtcagc atttttatga cgaccagaat aacaacgctc
     8941 gccgccaccc acagtaaatg ggtataaagt acgccgagat ttagcgacat accgacggag
     9001 ataaagaaca gcccaagcag taaaccttta aagggatcga tagcattttc cagctcatgc
     9061 cggtattcgc tctctgccag taaaacgccg gcaatgaagg ttcccagggc catcgacagt
     9121 cccagcgcat ccataaataa ggcggcgctc aacaccagca acagcgtcgc ggcagtgaag
     9181 acctcccgca cgccagacgc agcaataaaa cgaaataccg ggcgcagcag gtaacgaccg
     9241 ccaatcagca ttaccgcgaa agccagtacc ttcattgcca ctttaaacca gtcgaaatgc
     9301 tcgtcggccg atcccgccaa taaaggcacc aacgccagcg cggggatcac cgctaaatcc
     9361 tgaaacagta agacggaaaa ccctaactgc ccggactcgc tacgattcat gcctttctcg
     9421 cgcatcagtt gtagcgccat cgccgtcgaa gacatcgcca ggccaatccc gccgacgacc
     9481 gccgcctgcc ataagaaatc agcaagcatc aataatcccg ccagcaccgc cgcgcttaac
     9541 agcacctgag cagcgccgac gccgaagata gagcgccgca gttgccaaag ccgtgacgga
     9601 ttgagttcga gaccaatgat aaacatcaga aacacgacgc ccagttcgga aaagtgcagg
     9661 atctcgtcaa catcgctgat aaatcccagc ccccacggac cgatggcgat tcccgccagc
     9721 aaatacccta gcaccgcgcc gatgcccagc ctcgcggcca gcggcaccgc cgctaccgcc
     9781 gcgaagagga acaacactcc cgcggtcaat aaatcagcac cttccatcaa tagcctcccg
     9841 cgctcacagg attcgccagc cactcgccat aggctttcgc atgactggcc agcgtctgcg
     9901 gcgactggcg gcgcgcccag tacacaataa tgggcggcat ccagtgcatc cggcacatgg
     9961 ccgcggtcag ttcaaaaggg cggagtacat cgctcattgg atagcggttt agcgcgtcat
    10021 accggtaagc gctctccggc tcgccggtcg taatcacgct acgccagtac tttcccacca
    10081 gttggtttcc ccctggtccg ctggcgaacc ctcgactcaa aacgcgatca agccattctt
    10141 tcagtaaagc cggacagcta taggtgtaaa ggggatgctg aaaaacaatg acgtcgtgct
    10201 cacgtaacag ggcttgttca tagggcgtat cgataaaaaa atcaggatag cgcgcataaa
    10261 gatcgtgcac ggttacgtta ttgtgctgta tggccggttt aagcagtacc cggttagcaa
    10321 ccgagtcctg agattccgga tgggcataca acagcaagac tttcgctggc tgagacatca
    10381 atccccctcc cggttgtttt gggtcgatac atgccattct tcaggccgct tctacgttga
    10441 cagcgtttgt tcaactcaga aacgtactcc atgtccgccg ctggggatta atgagagata
    10501 ttcttgtccc tcaccaaagg cggcctgaat gattttgtgt atcgttgttg ttttgagcta
    10561 ccattgcgct ccagcgcggc ggtacgcccg aatattacat tatcataatg ataaattaac
    10621 atagtctgaa catacggcgc cttatgattg ttttctcctc gttacaaatt cgtcgcggcg
    10681 tgcgcgtcct actggacaat gcctcggcta ccattaatcc aggccagaaa gtcggcctgg
    10741 tgggtaaaaa cggctgcggt aaatctaccc tgctggcatt gctaaaaaat gaaatcagcg
    10801 ccgatgccgg gagttttacc ctgcccggaa cctggcaatt agcgtgggtg aatcaggaaa
    10861 cacctgcgtt gcctcagcca gcgattgagt atgtcattga cggcgaccgt gaataccggc
    10921 atctggaggc gcagcttaac gacgccaacg aacgtaacga cgggcatgct atcgcctcca
    10981 tacacggtaa gctggacgcc atcgacgcat ggaccgttcg ctcgcgcgcc gccagcctgt
    11041 tacacggcct cggcttctct aacgatcagc tggaacgtcc ggtcagcgac ttttccggcg
    11101 gctggcggat gcgccttaat ctggcccagg cgctgatttg ccgttccgat ttactgctgc
    11161 tcgacgaacc gaccaaccac ctcgatctgg atgccgttat ctggctggaa aaatggctga
    11221 agagctatcc aggcaccctg attctgatct cccacgatcg cgattttctt gacccgatag
    11281 tggataaaat tatccatatc gaacagcaga ctctgttcga gtacaccggt aactacagcg
    11341 cgtttgaagt tcagcgcgcc acgcgcctgg cgcagcagca ggcgatgtat gagagtcagc
    11401 aggagcgtgt ggcgcatctg caaagctaca tcgaccgttt ccgcgccaag gccaccaagg
    11461 ccaagcaggc gcaaagccgt atcaagatgc tggagcgtat ggagttgatt gcgccggctc
    11521 atgtcgacaa cccgttccat ttcagcttcc gcgcgccgga aagcctgccg aacccgctgc
    11581 tgaagatgga aaaagtcagc gcaggttatg gcgatcgcat cattctggaa tccatcaagc
    11641 tgaacctggt gcccggctcg cgtatcggcc tgctgggccg caacggcgcg gggaaatcga
    11701 cgctgatcaa gctgctggcg ggcgaactgg aaccgttgca cggtgaaatc ggcctcgcca
    11761 aaggcattaa gctcggctac ttcgcccagc accaactgga gttcctgcgc gccgatgaat
    11821 ccccgctgca gcatatggcg cgtctggcgc cgcaggaact ggagcagaag ctgcgcgact
    11881 atctcggcgg cttcggtttc cagggcgaca aagtaacgga agagacgcaa cgtttctccg
    11941 gcggcgagaa agcgcgcctg gtactggcgc tgatcgtctg gcagcgtcca aatctgctac
    12001 tgctcgatga accaaccaac cacctggatc tcgacatgcg tcaggcgctc accgaagcgc
    12061 tgattgattt cgaaggcgca ttggtcgtcg tgtcgcacga ccgccacctg attcgctcca
    12121 ccaccgacga cctctatctg gttcacgaca aaaaggtcga accgttcgac ggcgacctgg
    12181 aggattatca gcagtggctg agcgacgtgc agaagcagga aaaccaggcc gacgacgcac
    12241 cgaaggaaaa caacgccaac agcgctcagt cacgcaaaga tcagaagcgt cgcgaagccg
    12301 agctacgcac tctaacgcag ccgctgcgta aagagattac ccgtctggaa aaagagatgg
    12361 aaaagctcaa cgcccaactg gcgcaggcgg aagagaagct tggcgacagc agcctgtatg
    12421 acccaagccg taaagcggag atgaccgagt gtctgcaact gcaggccagc gccaaatccg
    12481 ggctggaaga atgtgaaatg gcatggcttg aggcgcagga gcagcttgag cagatgatgc
    12541 agaacgacta agagcctatc ccattaggct attttattcg ccattttagg gccgggcagt
    12601 gctcgaaatc ctcacggttt ctgcgcgctg tccggcccca aactggcttc aacaattacg
    12661 cctactggga taggctctaa cgcacggggc ggacgatgaa cctgtctatc accgatgaca
    12721 ttaccttccg caagctcacc atcttcatga tgcttgtgga gaagggtaac atcgcccgca
    12781 ccgccgagac gctgcacacg ctggaagaga acgttcgttg tccactgttc gtccataaag
    12841 gcctcttcgg tactcgtccc gatataaagg ttaccgttgc ggtcggcagc accggaacag
    12901 aagcctgcgt tatgtgagtt agcggcaaag gttgccgtga tttattttcg tcagcgcgtc
    12961 gttcacgcca aataatgtaa acgtcacctc atcaacgcca agatttttca gacgcgcagt
    13021 gtgtttttta atataagcct gcgccgtttc ttcggattca aacaagtaaa tgccgccagc
    13081 ttgctggttt ttctcgcttt ctgtccagat tttccagatg aagcccggct cctcattgat
    13141 agactccgcc agcccgacca gttgctgagt catctcctcg ccaaaagggc cgctaaagtt
    13201 aaaatggatc tgtaaaagtg tcttcgacat gccttctcct tgagtcacat aactatcgtg
    13261 ttgccacact accacgatta attcggctga tgcagaggtt cacgcgattt ctgtggggta
    13321 ttgcgcgcgc cttgcatacc gccccctctg gtgaaatgag gcgcaatttt atttcgccag
    13381 acgaccaatt gaacgtaaaa tcacatattg actaatctgt gaaccttatg cgcggtatag
    13441 tattgtttcc aattatcaat tgttctggtg ctatggttga gatcacgtcc acagaaatga
    13501 ccccgcctgt caatgactcg catgaattta ttcccatgcg tggcattcgt aatcgccatt
    13561 tacaaactat gctgccacgt ttaatccgcc gcaaagtgaa gttcaacgcc cactggcagc
    13621 ggctggagct accggacggc gattttgtcg atctggcatg gagcgaagaa ccgcaacagg
    13681 caaagcataa agcgcggctg gctgggcgtg gtgatgcact ttcgcggctg tagcggcgaa
    13741 cccaaccgtc tgaatcgtat ttaccactcc ggtgaaacgg aggacggagc ctggttttta
    13801 cgctggctac agcgggagtt cggcgccgtt ccgacagccg ccgtgggcta ttcgctcggc
    13861 ggtaatatgc tggcgtgcct gctggcgaaa gaaggccgcg atattcccat cgaggcggcg
    13921 gtaattgttt ctgcgccttt cgttctcgaa gcctgtagct accacatgga caaagggttt
    13981 tcccgcgtct atcagcgtta tttgcttaat ctgttaaaag cgaatgcgtc acgcaagctg
    14041 gcggcgtatc ccgggtcgct gccggtgaat ctggcgcaac tgaaatcaat gcgccgtatt
    14101 cgcgaatttg acgacctgat caccgcgaaa attcacggct ttgccgacgc catcgactac
    14161 tatcgtcagt gtagcgccat gccgttgctt aaccagattg ctaaaccgac gctgattatt
    14221 cacgctaaag acgatccgtt tatggatcat catgtgatcc ctaaagcgga agatctgccc
    14281 ccgcaggtgg agtatcagct gactgagcat ggcggacacg taggatttat cggcggtacg
    14341 ccactgcgcc ctgaaatgtg gctggaacgc cgaattcctg actggctgac aacgtacctg
    14401 gaggcgtcat catgatcatt ccctggcagg ggctcgcccc cgacacgctg gacaacctga
    14461 tcgaaagctt tgtgttgcgc gaaggcaccg attatggtga acatgaacgt tcgcttgaac
    14521 aaaaagtcgc tgacgtaaaa cgccaactgc aatccggcga ggccgtgctg gtatggtctg
    14581 aattacatga aacggtcaat attatgccga aaaagcagtt tcgcgaataa aacgcctttg
    14641 ccgacaatac attattaata aagctcaatc atggagttgc catgtcagcc aaacatccgg
    14701 tgatagcagt aacagggtca agcggcgcgg ggaccaccac caccagcctc gcgtttcgta
    14761 aaattttcgc gcagttaaat ctgcatgccg ccgaggtgga aggcgacagt tttcatcgtt
    14821 acacccgccc ggaaatggac atggcgatcc gcaaagcgcg tgacgccggg cggcatatca
    14881 gctatttcgg gcctgaagcc aatgacttca gcctactgga acataccttt attgagtacg
    14941 ggcagacggg taaaggccag tcgcgtaaat atctgcatac ctatgatgaa gccgtaccgt
    15001 ggaatcaggt tcccggcacg tttaccccct ggcagccgct tcctgaaccg accgatgtgc
    15061 tgttttatga aggactgcac ggcggcgtcg tcaccccaca acatgatgtc gcgcgtcatg
    15121 ttgatctgtt ggttggcgtg gtgcctatcg tcaaccttga gtggattcag aaactaatcc
    15181 gcgacaccag cgagcgcgga cactcccgtg aagcggtgat ggattccgtg gtgcgttcca
    15241 tggacgacta catcaattac attacgccgc agttctcgcg tacccatatc aacttccagc
    15301 gcgtaccgac cgtcgacacg tccaatccgt tcgccgcaaa gggtattccc tcgctggatg
    15361 agagttttgt ggtgatccat ttccgcaacc tggaagggat cgattttccc tggctcctgg
    15421 cgatgctcca gggctcgttc atttctcaca ttaatacatt agtggtgccg ggcggcaaaa
    15481 tggggctggc gatggagctg attatgttgc cgctggtgca gcgattaatg gaaggcaaaa
    15541 aaatcgaata accgcggtga aatgcccgat ggcgctacgc ttatcgggcc tacgagataa
    15601 aaacgggtag gccggataag gccacgccgc catccggcat cacgtgttac gccgcaatca
    15661 cttcatacga atgggtaata ttgaccgctt tttccagcat tagcgccacc gagcaatatt
    15721 tttccgcgga gagatcgaca gcgcgcgcga cggcagcctc tttcagatcg ccgccggtaa
    15781 cgataaaatg caaattaatg tgcgtaaaca ggcgcggcgc gtcttcccgg cgctcggatg
    15841 ttagcttcac ttcgcagttg gtgacattct gacggccctt ttgcagaatt gataccacat
    15901 caatagcgct acatccgcca gccgccatta ataccatctc catcgggctc ggcgctttgt
    15961 caccggagtt accatccatt aaaatctggt ggccggagga ggactctccg aggaacgtga
    16021 gtccttcaac ccactttaca cgcgcttgca tatttcgtaa ctccaatgtt tcaattttcc
    16081 tgaaagatta cgcgcataca acaaaactcg caatggaagg cgacctgggt catgctgaag
    16141 cgagacacca ggagacacac ggcgaaagct atgctaaaac agacaagatg ctacagtaat
    16201 acattgacgt actgcatgta tgcagaggac atcacattac aggctacaat ctattttcgt
    16261 agcccccttc ccaggtagcg ggaagtatat ttttgcaacc tcagagacag tgccgttttc
    16321 tggctctgga gacagcttat aacagaggat aaccgcgcat ggtgcttggc aaaccgcaaa
    16381 cagacccggc tcttgaatgg ttcttgtctc attgccacat tcataagtac ccgtcaaaga
    16441 gcacgctgat tcaccagggt gaaaaagcag aaacgctgta ctacatcgtt aaaggctccg
    16501 tggcagtgct gatcaaagat gaagaaggga aagaaatgat cctttcttat ctgaatcagg
    16561 gtgattttat tggtgaactg ggcctgtttg aagaaggcca ggaacgcagc gcctgggtac
    16621 gtgcgaaaac cgcatgtgag gtcgctgaaa tttcctacaa aaaatttcgc caattaatcc
    16681 aggtcaaccc ggatattctg atgcgcctct cttcccagat ggctcgtcgc ttacaagtca
    16741 cctctgaaaa agtaggtaac ctcgccttcc ttgacgtcac cgggcgtatc gctcagacgc
    16801 tgctgaatct ggcgaaacag cccgatgcca tgacgcaccc ggatgggatg cagatcaaaa
    16861 tcacccgtca ggaaatcggc cagatcgtcg gctgctcccg cgaaaccgtt ggtcgtattt
    16921 tgaaaatgct ggaagatcaa aacctgatct ccgcgcatgg caagaccatc gtcgtctacg
    16981 gcacccgtta atcccgtcag aatggcgcgt tttatcatgc gccatttttg tttgcatcga
    17041 tgtggcgaag actgatttat cacccagaga ttaattacgc actacggcaa acgctggtgc
    17101 tgtgcctgcc tgtggctgtt ggtttattga taggccagct acacctgggc ttgcttttct
    17161 ctctcgttcc cgcctgctgc aacattgcag gtctggatac cccgcacaaa cgctttttta
    17221 aacgcctgat catcggcgcg tcgctgttcg ccggatgcag tctggtaacg caacttctgc
    17281 tggcggaatc catccccctg ccgttgatcc tgaccgggct cacgctggtg cttggcgtga
    17341 cggcggaaat tagcccgctt cacgcgcggc tactgccagc gtcgctgatt gccgccatct
    17401 ttaccctgag ccttgcggga tacatgcccg tctgggagcc gctgctcatt tatgcgctgg
    17461 gcacgctatg gtacggcgtg tttaactggt tttggttctg actatggcgc gaacagccgc
    17521 tgcgcgagtc attgagtttg ttataccgtg aactggccga ttattgtgaa gcgaaataca
    17581 gcctgctcac ccaacatatc gatccggaaa aagcgctgcc tcccctgctg atacgccagc
    17641 aaaaagcggt cgatctcatt acccagtgtt accaacagat gcatatgctt tcggcgcaca
    17701 acaataatga ttacaagcgt ctactacggg cttttcagga agcgatggat ttgcaggagc
    17761 acatctccgt cagcttgcat cagccggaag aggtacagaa actggtagaa cgcagccatg
    17821 cggaagaggt gattcgctgg aatgcgcaaa cggtcgccgc ccgtctgcgc gtgctggcgg
    17881 atgacattct ttatcatcgt ctgccgacgc gcttctccat ggaaaaacag attggcgctc
    17941 tggagaagat cgctaatcag catcctgaaa atccggtagg ccagttctgc tattggcact
    18001 tcagtcgaat cgcccgtgtg ctgcgtactc agcggccgct gtacgcccgc gacctgatgg
    18061 ccgataaaca gcgtcgtctg ccgctacttc cggcgctgaa aaattatatg tctctaaaat
    18121 cgccggcgct acgcaacgcc ggacgcatca gcgtgatgat gagcatcgcc agtctgatgg
    18181 gcagcgcgtt gcacctgcct aaaccgtact ggatcctcat gacggtgctg tttgtcaccc
    18241 aaaacagcta tggcgcgacg cgcgtacgta ttctgcaccg ttcggtcgga acgctggtcg
    18301 gcctggtgat tgccggcgtc acgctgcact tacatattcc cgaaagcatt acgctggcgg
    18361 tcatgctggt actaacgctg gcaagttatc tgattattcg taaaaactac ggctgggcga
    18421 cggtcggctt tacggtgacg gcggtataca ccatccagtt actgacgtta aacggagagc
    18481 agtttattgt gccgaggctg atcgatacgc tgattggctg tttaattgcc tttggcggca
    18541 tggtctggct gtggccgcaa tggcaaagcg ggctattacg taaaaacgcc catgatgcgc
    18601 tggaagccga tcaagaagct atccgactga tcctcagtaa cgatccgcag gccaccccgc
    18661 tcgcttatca aagaatgcgg gtcaaccagg cgcataacac gttattcaac tcgttaaatc
    18721 aggcaatgca ggaacccgga ttcaataccc actatctgtc ggatatgaaa ctgtgggtca
    18781 cgcacagcca gtttattgtc gagcatatca acgctatgac gacgctggcg cgggaacaca
    18841 ccatgctgac gcctgatctg gcgcagcgct atctggaatc ttgcgagatt gcgattcagc
    18901 gctgccagca gcgcctagag tacgacaggc caggcggctc cggcgatgtc aatattctgg
    18961 agtcgccgga catgctgtca catggcttat tgagcactct ggaacaacat ttacagcgca
    19021 tcattggcca tctgaacacc atgcacacca tttcgtcgat ggcctggcgt cagcgtccgc
    19081 atcacggtat ctggctgagt aagcggctac gggatacaaa aggttaagac cgactgccgg
    19141 atgcgctacg cttatccggc aatccgccat caggccacca ccttccctac cgcctgcgca
    19201 aagcgctgca ttccttcatt gatatccgcc tcttccacca ccagcgacgg ggcaaaacgc
    19261 atcacgtcgg ctccggcatt gagcaccatc acgccggcct ccgcgcctgc gtacagaaaa
    19321 tcgcgcgccc gacctttgta cttcggcttc agttccgcgc caatcagcag ccccatgccg
    19381 cgaatatcgc tgaaaatgtc aaattgctcg tcaatcgcct gcaaatgttg cacaaactgt
    19441 tgccgcttag tgtgaatgcc ttgtagtacc tctggcgtat taataatatc gaatgccgcg
    19501 ccagccaccg cacaggccag cggattgccg ccataggttg aaccatgcga accgacatgg
    19561 aaggccgagg cgatctcctg cgtggtcagc atggcgctca ccggaaaacc gccgcctaac
    19621 gctttggcgc tggtgaggat atccggcgtg acgccgtagt gcatataggc aaacaggtct
    19681 ccggtgcgcc ccatcccaca ctgcacttca tcaaacacca gcaacgcctg atgcttgtca
    19741 cacaggtcgc gtaacccttt gaggaattcc ggtgtagccg cctgcacgcc gccttcaccc
    19801 tgaatcggct cgactaccac cgcgcaggtg tggtcatcca ttaccgcttt caccgcatga
    19861 agatcgttga agggaacgtg aataatatcg gcgggtttcg gcccaaagcc gtcggaatat
    19921 ttcggctgcc cgcctacaga gacggtaaac aaggaacggc catgaaaggc gttctggaag
    19981 gcaatgattt tcgttttgaa cgggctatgg cgcacgcagg cataatgacg cgccagttta
    20041 aaagcggttt cgttcgcttc ggtgccggaa ttcataaaca gcacgcgctc ggcaaacgtg
    20101 gcgtcgatca gtttacgtcc cagacacaac gccggttcat tggtaaaaac gttactggta
    20161 tgccacaagg tttccccctg ggatttcagc gcctcgacca gtgccggatg gcaatggccc
    20221 agcgcagtca ctgcaatccc gccggcgaaa tcgatatact ctttgccctg ctgatcccat
    20281 acgcggctgc ctttaccttt gaccggaata aagtccgccg gtgcataaac aggcagaatt
    20341 acctcatcaa aagttgcgcg cgtaatagcc gtttgttcag ttgccatatc attaccaccc
    20401 ggttaagtag aaatgccagt gaaattataa tcacaaaata tgaataaaaa atcactcaat
    20461 agcaaccaca aatcaacgcc ggaggaaatt ttccagcaga gcgtgtcctt gttcgctgag
    20521 aatactttcc gggtggaact gcacgccttc cagatcccac tcgcggtggc gaatgcccat
    20581 aatctcctgc gtttcgctcc aggcggtgat ctcaaaacac tcaggcaacg tggcagggtc
    20641 gacaatcagc gagtggtaac gtgtcacggt taacgggctg ggcaatcccc gaaacacgcc
    20701 ctgtccatta tgcgtaacag gtgacgtttt accgtgcatc actttcgctg cccgcaccac
    20761 cgacgcgcca aaggcctgcg ccatcgcctg atgacccagg caaacgccca gcatcggaat
    20821 acgtccggca taatggcgga tgaccgccag tgaaatgcca gcgtcatttg gcgtacaggg
    20881 gccaggagag ataacgattt tttgcgggtt caaagcgtca atgtgcgcca gcgtcagcgc
    20941 atcattgcgc cgaacctgca cttccgcgcc cagttcacaa aaatactggt agaggttcca
    21001 ggtaaaggaa tcatagttat cgataagcag gatcatggcg gctccgggtc agtagaaccg
    21061 ccctatttta ctcagtttcg cgagcttcgc ttatcgcttt ctgaaaaatc gcccgcaaag
    21121 cggagagatc gcccatcgcg ccgctctggt tcgcctgatt ccatgtttca accgcaatac
    21181 cttgccaact cagcgcgtag cctgcatgta gcgccagttg ttcaaagaag atgcgctgcg
    21241 ccagcccgct ccccaaacga aacggatgaa gcacattaat ttcacagtag taatgcgcca
    21301 gccgctcgac aaacttctcg tgcgtcagac caaccaggta gccctcttct tccagatcct
    21361 gcatcagggc attgccctct ttttcgatat aggcaaagtg gcagaaacgg gtatcgccct
    21421 ggtaaatatc gacctcccgc agttgccctg cccagtcgaa aatatcctga tagagctggc
    21481 gatgaatcgc gcacagatga ggcaagccgc gtaccagcgg ccccagttca atcgtagcgg
    21541 cgcggagcgc ggtcatttcg tatgccgctt gcgccagtcg ctgggcctga tgaatcccca
    21601 gccgattacg catcacattc agccccggat agaggtacgg atcgcgccct tcgccaaatt
    21661 tatcgctcat agtgcctccg aagctcgtca agacgtgcca gcgcttcatc ggcggtcagg
    21721 gttactaagg ggatctcaat accttcgaga cggcggcttt gctggaagtt aacgttgcgc
    21781 cgctgttccc aaaagcgtga cttttgttta tcggtaagtt tcttcacctg gcctccctga
    21841 atatgcctgt gattgaccac aagtataagc agcaatttca ggttacgctg agacagggag
    21901 aaaacgcggg cggctcgcac ccgcgcaggc atgttttatg gcaggacttt cgcggaaagg
    21961 ataacgactg gttttgtcgg cacattctga taaggcccga catcgtgcgt cggtacctgt
    22021 gagattttat cggcgacatc catacctttt accactttac caaataccgc atagccaaag
    22081 tcgcgctggc cgtggtcgag aaaagcgtta tccgcgacgt taataaagaa ctggctggtg
    22141 gcgctgtctt tatctgcggt gcgagccatc gcgatcgtgc cgcgagtatt acgcagaccg
    22201 ttgtcggctt cattcttaat aggcggattc ggtttcttct gctgcatctg ctcgttaaaa
    22261 ccaccaccct gaatcataaa gccaggaata acgcggtgaa acgtagtgtt gttatagaaa
    22321 ccactgttga cgtaatcgac aaagtttttc acagaaaccg gcgctttctg gctgttcagc
    22381 tccagctcaa tattcccggc ggaggtggtt aacagcacat gaggatcacc ttttgctgcc
    22441 aacgctacgg gagaaagagc agaaagagcg aaaacagctg cgacagccgc cagagtcgat
    22501 ttgagcatga gatttcctta aagagagcag aaataaagca agtggaatga ttctaaagag
    22561 ccttcctggg ccaggccagc cctttaccta attttacgta catgaaacaa atgtaacgtt
    22621 acgacgcaac gccttgtcct tgcaatatga tgtgacaaac atcacattaa aaaatgtaat
    22681 gaacattact atcactaata attatttaaa tacatcacaa aagcgcttaa aatctgcccg
    22741 cttaacgcgc cctccacgcg cttcacttct cttcaaggcc agacatgact aacagcaacc
    22801 gcatcaagct cacatggatc agctttcttt cctacgccct gaccggggcg ctggtgattg
    22861 tcaccgggat ggtgatggga aatatcgcag actattttca gttgcccgtt tccagcatga
    22921 gtaacacctt tactttcctg aatgccggga ttttgatctc gatcttcctc aatgcgtggt
    22981 tgatggaaat cgtcccgctg aaaacacagc tacgctttgg ttttatcctg atggtactgg
    23041 cggtggccgg gctgatgttc agccatagcc tggcgttgtt ctcagcggcg atgtttgtgc
    23101 tggggctggt cagcgggatc accatgtcga ttggcacctt cctgattacg caactgtatg
    23161 aagggcgtca gcgcggttcc cgactgctgt ttaccgactc cttcttcagc atggcgggga
    23221 tgatttttcc tatggtcgcc gccttcctgc tggcgcgtag tattgagtgg tactgggtct
    23281 acgcctgcat cggcctggtc tacctggcga tttttatcct gaccttcggc tgtgaatttc
    23341 cggcgctggg taaacatgcg cagcactctc aggcgcctgt cgtcaaagaa aaatggggca
    23401 ttggcgtact gtttctggcc gtcgccgcgc tgtgctatat cctcggtcaa ttgggcttta
    23461 tctcctgggt gccggaatac gccaaaggcc tcggcatgag cctgaatgac gccggggcgc
    23521 tggtgagtga tttctggatg tcctatatgt ttggcatgtg ggcgttcagc tttatcctgc
    23581 gctttttcga tctgcaacgc atcctgaccg tactggcggg tatggcggcg atactgatgt
    23641 atctgtttat taccggcacg caggcgcata tgccgtggtt tattctgacg ctgggcttct
    23701 tctccagcgc catttatacc tccatcatta cgctgggatc gcagcaaacg aaagtggcct
    23761 cgcctaagct ggttaacttt attctgacct gcggcaccat cggaacgatg ctgaccttcg
    23821 tcgtcaccgg cccgattgtg gctcacagcg gcccacaggc ggcgttactc accgcgaatg
    23881 gtctgtatgc ggtggtcttt gtgatgtgct ttgcgctcgg ctttgtctcc cgtcatcgcc
    23941 agcatagttc gccagcggcg cattaataat gattgccgga tggcgacgcg atgcgtctta
    24001 tccggcctac agcgtaagct gttggtaggc cggataaggc gacgtcgccc tccggcactc
    24061 tatccccccc tgacgaggta ggcttgttgg tctaaaaacc cctcattttg tatgttattt
    24121 gtacaaacct gaaaagcctg acaattccgc cacttataaa aacccagaca aatcagccat
    24181 atacccatta agaggtatat aaaggtgaat ttgatttaca tcaataagcg gggttgctga
    24241 atcgttaagg taggcggtaa tagaaaagaa atcgaggcaa aaatgagcaa agtcagactc
    24301 gctattatcg gtaatggtat ggtcggccac cgctttattg aggatctcct tgataaatcc
    24361 gacgctagcc tgttcgacat taccgtgttc tgtgaagaac cccgtaaagc ctatgaccgt
    24421 gtccacctgt catcctactt ctctcaccac accgcggaag agctctctct ggtgcgtgaa
    24481 ggattttacg agaagcacgg cgtaaaggta ctggttggcg aacgcgcaat taccattaac
    24541 cgtcaggaga aagtgattca ctccagcgcg ggtcgtaccg tttattatga caagctgatc
    24601 atggcgaccg gttcctatcc gtggattccg ccgattaaag gctccgaaac ccaggattgc
    24661 ttcgtttacc gtaccattga agacctcaac gctatcgaag cctgcgcccg ccgcagcaag
    24721 cgcggggcgg tggtcggcgg cggtctgctg gggctggaag ccgctggcgc gctgaaaaac
    24781 ctcggcgtgg aaacgcacgt cattgaattt gcgccaatgc tgatggcgga acaactcgat
    24841 caaatgggcg gcgagcagct acgtcgcaag atcgaaagca tgggcgtgcg tgtacacacc
    24901 agtaaaaaca cgcaagagat tgttcagcag ggtaacgaag cgcgtaagac tatgcgtttt
    24961 gccgatggca gcgagttgga agtcgatttt atcgtcttct ctaccggtat tcgcccccgc
    25021 gacaagctgg ctacccagtg cggtctggcc gtcgcgcagc gcggcgggat cgtgattaac
    25081 gacacctgcc agacgtccga cccggatatc tacgctatcg gcgagtgcgc cagttggaac
    25141 aaccgcgttt acggtctggt cgcaccgggc tataaaatgg cccaggtcgc cgttgaccat
    25201 atcctcggca gtgaaaacgc ctttgaaggc gcggatctca gcgccaaact gaagctgctg
    25261 ggcgtggacg tcggcgggat tggcgatgcg catggccgca cgccgggcgc gcgtagctac
    25321 gtttacctcg atgaaagcaa agaagtctac aaacgtctta ttgtcagcga agataacaaa
    25381 acgctgctcg gcgcagtact ggtcggcgac accagcgatt acggcaattt gctgcaactg
    25441 gtactgaacg ccatcgaact gccggaaaac ccggattcgc tgatcctgcc gtcgcacgcg
    25501 agcagtggta aacccgctat cggcgtggat aaactgccgg acagcgcgca gatctgctcc
    25561 tgcttcgatg tgactaaagg cgatctgatc gctgctatca ataaaggctg ccataccgtg
    25621 gcagcgctga aagcggaaac caaagccgga accggctgcg gcggctgcat cccgctggtg
    25681 acgcaggtac tgaacgccga actggcgaaa cagggtattg aagtcaacaa caacctgtgc
    25741 gagcactttg cttattctcg tcaggaactg ttccacttaa tccgcgtgga aggtatcaaa
    25801 acctttgaag aactgctgac gaaacacggt aaaggctacg gctgcgaagt gtgtaagcca
    25861 accgtcggtt cgctgctggc gtcgtgctgg aacgaataca tcctcaaacc gcagcacacg
    25921 ccgctacagg atactaacga taacttccta gcgaatattc agaaagacgg cacctactcg
    25981 gtgatcccgc gctcggcggg tggtgaaatc acgccggaag gtctggtggc cgtgggtcgt
    26041 atcgcccgcg agtttaacct ctataccaaa atcaccggtt ctcagcgtat cggtctgttc
    26101 ggcgcgcaaa aagacgatct gccggaaatc tggcgtcagt tgattgaagc cggtttcgaa
    26161 accggtcacg cgtacgccaa agcgctgcgg atggcgaaaa cctgcgtcgg cagcacctgg
    26221 tgccgctacg gcgtgggcga cagcgtcggt ttcggcgtgg agctggaaaa ccgctacaaa
    26281 ggcattcgta ccccgcacaa aatgaaattc ggcgtctccg gctgtacccg tgaatgtgcg
    26341 gaagcacagg gtaaagatgt cggtatcatc gccactgaga aaggctggaa cctgtacgtt
    26401 tgcggtaacg gcgggatgaa accgcgtcat gcggatctgc tggcagccga tctcgatcgc
    26461 gacacgctga tcaagtacct cgaccgcttt atgatgttct acatccgtac cgccgataag
    26521 ctgacgcgta ccgcgccgtg gctggataac ctggaaggcg gcatcgaata tctgaagtcg
    26581 gtcattatcg acgataagct gggcctgaac gaacatctgg aagaagagat ggcgcgcctg
    26641 cgcgcagcgg tggtctgcga gtggacggag accgtcaaca cgccagcggc gcaggttcgt
    26701 ttcaaacact tcatcaacag cgacaaacgc gacccaaatg tccaggttgt gcctgaacgc
    26761 gaacagcatc gtccggccac gccgtatgaa cgcatcccgg tcactctggt ggaggaaaac
    26821 gcatgagcca gtggcaaaac atctgcaaaa ttgatgacat cctgccggga accggcgtct
    26881 gcgcgctgtc aggcggcgag caggtggcga ttttccgtcc ttaccatagc gatcaggtgt
    26941 ttgcgatcag caacatcgac ccgttctttg aggccagtgt gctgtctcgt gggctgattg
    27001 cggaacacca gggcgaactg tgggtcgcca gcccgttgaa aaagcagcgc tttcgtttaa
    27061 gcgacgggct gtgcatggaa gatgagcagt tctctgtgaa gcattacgac gcgcgggtaa
    27121 aagacggcgt ggtgcagttg tgcggttaat tatttttggg aggcgcaacg cctccccttt
    27181 tttgacgtat ttgtaggtct tttattggta ggcctgataa gcgtagcgcc atcaggcaat
    27241 tgcaaaagca cattgccgga tggcggcata aacgccttat ccggcctacg gttacgattt
    27301 ttttgttttt tatacttcaa ggataatcaa atgtttacag acactattaa taagtgtgcg
    27361 gctaacgctg cgcgcatcgc acgcctgtcg gcgaataatc cgctcggctt ctgggtcagt
    27421 tcggcaatgg ccggggctta tgtcggtctc ggcatcattc ttattttcac cctcggcaat
    27481 ctgctcgacc cgtccgtgcg tcctttggtg atgggagcca ccttcggtat cgccttaacg
    27541 ctggtcatca tcgccggttc cgaactgttt accggccaca ccatgttcct gacgctgggc
    27601 gtcaaagcgg gcaccatcag ccacggtcaa atgtgggcta tcctgccgca aacctggctc
    27661 ggcaacctgg ttggttccgt gtttgtcgcc ctgctttaca gctggggcgg cggcagtttg
    27721 ttgccggtcg ataccagtat cgttcactca gtcgcgctgg cgaaaaccac cgcgcccgcc
    27781 acggtactgt tcttcaaagg cgcgctgtgt aactggctgg tttgtctggc aatctggatg
    27841 gcgatccgca ccgaaggcac ggcaaaattt cttgctatct ggtggtgtct gctggcgttt
    27901 atcgcttccg gctacgagca ctccgtcgcg aatatgacgc tgttcgccct ctcctggttt
    27961 ggccatcaca gcgatgccta taccctgtcc ggaatcggac acaatctgtt atgggtcact
    28021 ctgggcaata ctttgtccgg cgtcgtgttc atgggattgg gttattggta tgctacgccg
    28081 aaatcggagc gccctgttcc gcaaaaaacc aaccaaatta aggctacagc caaccattaa
    28141 ggggtaatgt cgtggaccat ttgcctatat tttgtcaatt gcgcgaccgc gactgtctga
    28201 tcgtcggcgg tggcgatgtc gcagaacgca aagcacggtt actgctggaa gcaggcgcac
    28261 gtttaacggt caatgcgcta acatttattc cgcagttcac cgtatgggta aatgaaggca
    28321 tgttgactct ggttgagggg ccgttcgacg aaacgcttct cgactcgtgt tggctggcga
    28381 tcgcggccac tgacgacgat accgtcaacc agcgcgtcag cgaagcggcg gaatcacgcc
    28441 gtatcttctg caacgtggtg gatgcgccga aagccgccag ctttatcatg ccctccatta
    28501 tcgaccgctc gccgctgatg gtcgccgtct cctccggcgg cacctccccg gtgctggcgc
    28561 gtctgctgcg cgagaaactg gaatcgctgc tgccgcagca tctggggcag gtcgcgcgct
    28621 atgccggaca gctccgcgcc cgagtgaaaa agcagtttgc caccatgggc gaacgtcgtc
    28681 gcttctggga aaaatttttc gtcaatgacc ggctggcgca gtcgctggcg aatgccgatg
    28741 agaaagcggt taacgcgaca actgaacacc tgtttagcga gccgctggat caccgtggcg
    28801 aagtcgtgct ggtcggcgcc gggccgggcg atgccgggct gcttacgctg aaaggattac
    28861 aacaaatcca acaggcggat atcgtggttt acgatcgcct cgtttccgac gacattatga
    28921 acctggtacg ccgcgatgcc gatcgggtct ttgtggggaa acgcgcgggt taccactgcg
    28981 tcccacagga ggaaatcaac cagatcctgc tgcgtgaagc gcaaaaaggt aaacgcgtgg
    29041 tacgcctgaa aggcggcgat ccctttatct ttggtcgcgg cggcgaagag ctggaaacgc
    29101 tgtgtcatgc cggtattcct ttctcagtag taccggggat taccgcggct tccggctgct
    29161 ccgcctactc cggtattccg ctaacccatc gcgattacgc acagagcgta cgtctggtca
    29221 cgggtcacct gaaaaccggc ggcgagctgg actgggaaaa cctggcggca gaaaaacaga
    29281 cgctggtgtt ctacatgggg ctgaatcagg cagcgactat ccaggaaaaa ctgatcgcat
    29341 tcggtatgga ggccaatatg ccggttgcgc tggtggaaaa cggtacctcc gtaaagcaac
    29401 gcgtcgttca cggtgtgctg acgcagcttg gtgaattagc gcaacaggtt gaaagcccgg
    29461 cgctgattat cgttggtcgc gtggtagcct tacgcgataa attaaattgg ttctct
//
LOCUS       DAJVKX010000047        29421 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.047, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000047 DAJVKX010000000
VERSION     DAJVKX010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29421
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.047"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            6..1418
                     /locus_tag="OPY25_002127"
     CDS             6..1418
                     /locus_tag="OPY25_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016150982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HCS0927738.1"
                     /translation="MLILVIAAGLWQLTPPSGLSAPAWHSAIIFVATIASIVAKVLPI
                     GAVGIIGITVFALAYAAGDKTASGAITTALSELNSSLIWLIVVAFMIARGFIKTGLGR
                     RIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIYPIADSLARSFDSHP
                     EDESRSKIGTFLITCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLSWGSWFIAAL
                     LPCLVSFLIVPLLVYWLTRPEIKHTPDAPDLARKELAQMGSMARGEWLMLATVGVLLV
                     LWIFGSSLGVDATTASFVGLSILLLSGVLTWEDVKSEKGAWDTLIWFAALLMMANQLK
                     KLGFTSWFGNLIGDSIGSTMHGTSWIIILLLLNAAYFYTHYFFASGNAQIAALYAVFL
                     GVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGIWWRTGFIISL
                     FNQAVFLTVGLAWWKVLGLY"
     gene            1463..1918
                     /locus_tag="OPY25_002128"
     CDS             1463..1918
                     /locus_tag="OPY25_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCS0927739.1"
                     /translation="MTCIFCQIVEGKAPCHKVWEDEHHLAFLSIFPNTDGFTVVIPKK
                     HYPSYAFDLPPQALADLMLATQKVAKKLDKAFPDVSRTGMFFEGFGVDHVHSKLSPMH
                     GTGDLAHWKPIESRQNKFFEQYEGYLSSHDHERADDEKLAALAARIREA"
     gene            complement(2054..4225)
                     /locus_tag="OPY25_002129"
     CDS             complement(2054..4225)
                     /locus_tag="OPY25_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HCS0927740.1"
                     /translation="MSAISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWNSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRKLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGETIDQIR
                     DVRNTAIMVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     ITVQPPRPKPWEKTYILLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYQRVPHPAYGNARIPAYEMIRFSINIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTDHTPTINLYRRARELKGIKKILIASGVRYDIAVEDPRYI
                     KELASHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDLYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKRHRFRLDQVQNFYPSPLANSTTMYYTGKNPLGKIGYK
                     SEDVVVPKGDRQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGGRRECLVPAPTIE
                     EMREARRQNRNTRPALTKHTPVEHQRQGLAANKKRGKGAGR"
     gene            complement(4359..5780)
                     /locus_tag="OPY25_002130"
     CDS             complement(4359..5780)
                     /locus_tag="OPY25_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4459 domain-containing protein"
                     /protein_id="HCS0927741.1"
                     /translation="MKKCFLFIFMCLFIFSANAELKFRPEIENKKIYFQGKVTDYTLN
                     DFIFFGDSREPFYGSENDDYTATADEWLRFYAELPDVRKWQRVVPDDFSMMSGAPWCD
                     IQFFEQENDHSVITGSEHTRCIDFLVTPKRKGLIPMGTKGTLLDYGSYLAFAPQIEHI
                     TLEGRFPEASRTWLQVRSVQTSATSIADLKIMLNEIYARHGYIFRPGGEMDRYFRQQP
                     WYRPRYANVDYLITETEHRNIKLLKELLSPESQRKKALYIQNTTDFCEALKANNIKYV
                     MDNTAEYLTTGADQPINLEKVWQKYRDLMINGGGNCQRDIESYKRYSFLYSEPLGIYY
                     NSTFEFDEKKGKYVLAYVNFDSSCNKEGDTIELEGMMVKREHVIEDNQGQHSDKDLEL
                     KTINLQCVAGAMMDQPDWDRYVQLILPPEKYNYYQRFIGKKITLRGKVMIAESMYHVT
                     PVLLNLLEEQNPIIKVADMPARP"
     gene            complement(5845..7269)
                     /locus_tag="OPY25_002131"
     CDS             complement(5845..7269)
                     /locus_tag="OPY25_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927742.1"
                     /translation="MDYINRWLGSELLMFCVLPWGYAAAVASLLILMFSKKRSRQILL
                     WVLLPQWAFVVLLLPTLQYTQLLSQTGTVWMLMLLLPILSWAGLLPALLLGTWLRKPW
                     PAWLLCHIVFIGMLCPVMPELWRAISYQWQQQNIAQLLRQVQAGDLRQLESIHDNSTL
                     EQTLVQAVKAPGISEKNLRDLTARVASPFRFSREDGYFVNAPFFAAFESGNITAVRIF
                     SEQLMGDSPQAQANRTIVRRQNPLEYLPTPRFKPEGFRQTFFEMADILLRVMPDLLTD
                     EAYSGAIQLQDKETLAFFWQRREAQNPLYRAYYFLLQGQTKALLAQIKLTPQVLGQSV
                     YPNKNLLASLFIDADGETLRALVKGQMLNWQHIPQDKLTDGWNFLISRTLHTASKEDA
                     LPPDILAGILQSMQQQHTALSEALIVASLDYQDERHSLMTAYRMAWLDCNKLNAMIDK
                     VYPPEDTRRTNVRIKLAQQCADLD"
     gene            complement(7285..8244)
                     /locus_tag="OPY25_002132"
     CDS             complement(7285..8244)
                     /locus_tag="OPY25_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001765108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927743.1"
                     /translation="MASVLTLAAEHRDTPENLLRYLAKIRGISPFLTAAESCPEAAIP
                     NAEFLYTPFATALRQHNVPIVRFFSQQLVGETSSARENRNIVARKENPLLTLYKSNYI
                     SQYREQYRLEISQLLLNIMPELLNDTVYIYPIIQRNTELVAYFWQKHPPTIPLRRLEA
                     MVLLAKTESLISEVTHNPEILITPPIERWDRENLLTFILSNGDLVMIQSLIDANVVDW
                     KRAMEDGNNEPLHQAILRLRGGALENALLIQIIKAMQAQKALSNEQIAHYLPWTPTFP
                     AAFLQAGLSCEQLREVLNALVVGSEQVLHDTRQRLNALCPVAK"
     gene            complement(8323..8706)
                     /locus_tag="OPY25_002133"
     CDS             complement(8323..8706)
                     /locus_tag="OPY25_002133"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927744.1"
                     /translation="MGESFAWMMWDSVILMSAWGIYGVVLLRLIVGAFDSLRYRRVFL
                     RVVLPQVSVVCVVWGGLFWIDSKDIYIVYLLISGLLPSIIIAIFSSRESPFFILGTIV
                     SHTIFLFVFVYVMDGPRLWHHIGED"
     gene            complement(8890..9501)
                     /locus_tag="OPY25_002134"
     CDS             complement(8890..9501)
                     /locus_tag="OPY25_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927745.1"
                     /translation="MVVLLLLLAHMGDILDRHHRRDAYQAQQVAEETLLRKIDTTDDR
                     VFLNHLMSQAMQPQNAGDWGTNRRIEHLAKRISPFDIAGGTEKIWLVLAIDRLNRSAV
                     GTFASWFIGDSVQAKQYRHQLLQNNPLLDLLNRVFNDSTADEQTFLQQQLLARDICTS
                     LISVVPELLTDELYAQAVAFDNSNKPEPFSWQFEFDVFYHQKK"
     gene            complement(9655..9801)
                     /locus_tag="OPY25_002135"
     CDS             complement(9655..9801)
                     /locus_tag="OPY25_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927746.1"
                     /translation="MRINEEGWRLLTFWMFTTGGYLILLFVVICLAFLFQTPRRVLLW
                     IALP"
     gene            complement(9822..11234)
                     /gene="ftsP"
                     /locus_tag="OPY25_002136"
     CDS             complement(9822..11234)
                     /gene="ftsP"
                     /locus_tag="OPY25_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HCS0927747.1"
                     /translation="MSFSRRQFLQASGIALCAGAIPLRANAAGQQQPLPVPPLLESRR
                     GQPLFMTLQRAHWSFTQGTRAPVWGVNGRYLGPTIRVWKGDDVKLIYSNRLAENVSMT
                     VAGLLVPGPLMGGPARMMSPNADWAPVLPIRQSAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDDISKTLPIPNHYGVDDFPVIIQDKRLDNFGTPEYSEPGSGGFVGDTLLVNGAQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRALHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMTNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     NLPMRLLPTEIMSGAPVRSRDISLGDDPGINGQLWDVNRIDITAQQGTWERWTVRADM
                     PQSFHIEGVSFLIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYYGQPSWPHFPFYFNS
                     QTLEMADRGSIGQMLVNPAS"
     gene            complement(11308..12045)
                     /gene="plsC"
                     /locus_tag="OPY25_002137"
                     /gene_synonym="parF"
     CDS             complement(11308..12045)
                     /gene="plsC"
                     /locus_tag="OPY25_002137"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HCS0927748.1"
                     /translation="MLYIFRLIVTVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAENYGNAIYIANHQNNYDMVTAANIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRAKAHSTIAAVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSNTSNKVNLNRLNNGLVIVEMLPPVDVSEYGKDQVRELA
                     AHCRALMEQKIAELDKEVAEREATGKV"
     gene            complement(12302..14560)
                     /gene="parC"
                     /locus_tag="OPY25_002138"
     CDS             complement(12302..14560)
                     /gene="parC"
                     /locus_tag="OPY25_002138"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCS0927749.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTE
                     AEIIIPRAEIRKIYENGRGSVRMRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGI
                     LASERKMNTLLKKELQADSDAYGDDRRSPLREREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKTLITL
                     PENAHVMPPLVIKDEHDMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKG
                     DDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGERGRRGTLMRGLQRIDRIEID
                     SPHRVSHGDSEE"
     gene            complement(14671..15537)
                     /locus_tag="OPY25_002139"
     CDS             complement(14671..15537)
                     /locus_tag="OPY25_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCS0927750.1"
                     /translation="MNDLISAAYSERLRRVCDHIERHLDEPLSLEALSRMAHSSPFHF
                     HRQFTVWSGLPLYRYIQWLRLRRASWRLAFNPQDKVIDIALDAGFQNPESFTRAFKTA
                     FGQSPCRFRQSPDWLAWHQRVPKLALQEQHVMDVKIVEFPPTRVAMLTHLGHPDKVNA
                     SAAKFIAWRRETGQSPIASSQTFGIAWHDPQTTPPAQFRFDICGSVRQPIAENDVGVV
                     NSEIPGGRCAVVRHQGSLDSLPESVWYLFREWLPASGETLRDFPVFFQYLNFVHEVAE
                     HELLTDIYLPLR"
     gene            complement(15609..16001)
                     /locus_tag="OPY25_002140"
     CDS             complement(15609..16001)
                     /locus_tag="OPY25_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiW/YdeI family stress tolerance OB fold
                     protein"
                     /protein_id="HCS0927751.1"
                     /translation="MKKLAAIVAVMALCSTPVLAAQQGGFSGPSATQTQGGGFVGPNG
                     SSTTVESAKSLRDDAWVTLRGNIVERISDDLYVFKDATGTINVDIDHKRWNGLTVTPQ
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            16153..16812
                     /gene="qseB"
                     /locus_tag="OPY25_002141"
     CDS             16153..16812
                     /gene="qseB"
                     /locus_tag="OPY25_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HCS0927752.1"
                     /translation="MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGKQEPVLILTARDALAERVEGLRLGADDYLCKP
                     FALIEVAARLEALVRRASGQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLEL
                     LLRNKGRVLPRKLIEEKLYNWDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGD
                     A"
     gene            16809..18158
                     /gene="qseC"
                     /locus_tag="OPY25_002142"
     CDS             16809..18158
                     /gene="qseC"
                     /locus_tag="OPY25_002142"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HCS0927753.1"
                     /translation="MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELF
                     DTQLMLFARRLSTLDLNELNAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDG
                     DNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
                     AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRP
                     LVEALNQLFSRIHSMMVRERRFTSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKAL
                     TQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSAVMDIYHPAQQANID
                     VRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGV
                     APEILTHIGERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW"
     gene            18265..18845
                     /locus_tag="OPY25_002143"
                     /pseudo
     CDS             18265..18845
                     /locus_tag="OPY25_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
     gene            18877..19191
                     /locus_tag="OPY25_002144"
     CDS             18877..19191
                     /locus_tag="OPY25_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCS0927754.1"
                     /translation="MLTVIAEIRTRPGQHHRQAVLDQFAKIIPTVLKEEGCHGYAPMV
                     DHAAGVSFQTLAPDSIVMIEQWESVAHLEAHLQTPHMKAYSDAVKDDVLEMNIRILES
                     GV"
     gene            complement(19316..21208)
                     /gene="parE"
                     /locus_tag="OPY25_002145"
     CDS             complement(19316..21208)
                     /gene="parE"
                     /locus_tag="OPY25_002145"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCS0927755.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDG
                     LNDYLGEAVNGLPTLPEKPFIGNFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVR
                     HFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGD
                     LADLDV"
     gene            complement(21236..21817)
                     /gene="yqiA"
                     /locus_tag="OPY25_002146"
     CDS             complement(21236..21817)
                     /gene="yqiA"
                     /locus_tag="OPY25_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HCS0927756.1"
                     /translation="MSTLLYLHGFNSSPRSAKACQLKNWLAERHPHVEMIVPQLPPYP
                     ADAAELLESLVLEHGGAPLGLVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVTEGGNHAFTGFEDYFNQIVDFLGLHSC"
     gene            complement(21817..22644)
                     /gene="cpdA"
                     /locus_tag="OPY25_002147"
     CDS             complement(21817..22644)
                     /gene="cpdA"
                     /locus_tag="OPY25_002147"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HCS0927757.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQA
                     VLEAIRAQQYEYDLIVATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQEAGISPAKRVLIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLL
                     ASPSTCVQFKPHCANFTLDTIAPGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY"
     gene            complement(22669..23091)
                     /locus_tag="OPY25_002148"
     CDS             complement(22669..23091)
                     /locus_tag="OPY25_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HCS0927758.1"
                     /translation="MKRYTPDFPEMMRLCETNFSQLRRLLPRNDAPGETVSYQVGNVQ
                     YRLTIVELTRYTTLVTIEQTAPAITYWSLPSLTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRFCLAHGAMAIPVY"
     gene            complement(23088..23720)
                     /gene="nudF"
                     /locus_tag="OPY25_002149"
     CDS             complement(23088..23720)
                     /gene="nudF"
                     /locus_tag="OPY25_002149"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HCS0927759.1"
                     /translation="MRKSDNLPVTFTKSDVEIIARETRYRGFFSLDVYRFRHRLFNGE
                     MSGEVKREIFERGHAAVLLPFDPERDEVVLVEQIRIAAYDTSVTPWLLEMVAGMIEEG
                     ETIEAVARREAMEEAGLTVGRTRPVISYLASPGGTSERSSILVGEVDATTAVGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAAAVIALQWLQLHHQELKNEWKK"
     gene            23921..25396
                     /gene="tolC"
                     /locus_tag="OPY25_002150"
     CDS             23921..25396
                     /gene="tolC"
                     /locus_tag="OPY25_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462101.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HCS0927760.1"
                     /translation="MQMKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKS
                     AADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDM
                     SKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQ
                     LDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELA
                     SLNVEHFKTDKPKAVNALLKEAENRNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTA
                     STGISDTSYSGSKTNSAQYDDSNMGQNKIGLNFSLPLYQGGMVNSQVKQAQYNFVGAS
                     EQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVD
                     VLDATTTLYDAKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPES
                     VAPETPEQDAAADGYNAHSAAPAVQPTAARANSNNGNPFRH"
     gene            25609..26280
                     /locus_tag="OPY25_002151"
     CDS             25609..26280
                     /locus_tag="OPY25_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HCS0927761.1"
                     /translation="MKRTKSIHHASFRKSWSARHLTPVALAVTAVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDAAGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSAAGTST
                     RSMGG"
     gene            26286..27449
                     /locus_tag="OPY25_002152"
     CDS             26286..27449
                     /locus_tag="OPY25_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HCS0927762.1"
                     /translation="MERVSITERPDWRDKATEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEDVTAELHQMCLKVVERVIASDELMTKFRIPKHTWGFVRQSWQTQQPSLYSRLD
                     LAWDGIGEPKLLENNADTPTSLYEAAFFQWIWLEDQINAGNLPEGSDQFNSLQEKLIE
                     RFAELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCAAEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVIANLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPDHPNLLPAYFAEDEHPPMDKYVVKPIFSREGANVSIIENGKTIESVEGPYGEEGMI
                     VQQFYPLPKFGDSYTLIGSWLINDQPAGIGIREDRALITQDLSRFYPHIFVEG"
     gene            complement(27511..28299)
                     /gene="ygiD"
                     /locus_tag="OPY25_002153"
     CDS             complement(27511..28299)
                     /gene="ygiD"
                     /locus_tag="OPY25_002153"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HCS0927763.1"
                     /translation="MSLTCMPALFLGHGSPMNVLDDNDYTRAWRRLGEALPRPQAIVV
                     VSAHWYTRGTGVTAMERPQTLHDFGGFPQALYDMHYPAPGSPALAQRLVELLAPVPVA
                     LDKEAWGFDHGSWGVLIKMYPNADIPMVQLSVDSTKPAAWHFEMGRKLATLRDEGVML
                     VASGNVVHNLRTVRWHGDNIPYPWAASFNDFVKANLTWQGPVEQHPLVNYLQHEGGAL
                     SNPTPEHFLPLLYVLGAWDGKEPITIPVDGIEMGSISMLSVQVG"
     gene            28440..29213
                     /gene="zupT"
                     /locus_tag="OPY25_002154"
     CDS             28440..29213
                     /gene="zupT"
                     /locus_tag="OPY25_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HCS0927764.1"
                     /translation="MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIM
                     LLISLMEMLPAALDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLP
                     GSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG"
BASE COUNT         6957 a         8116 c         7482 g         6866 t
ORIGIN      
        1 cattcattct tattctggtt atcgccgccg gactgtggca gctaacgccc ccttccgggt
       61 taagcgcgcc ggcctggcat tccgcgatta tttttgtcgc gacgatcgcc tctatcgtgg
      121 cgaaagtgct gcctattggc gcggtcggta ttatcggcat caccgtcttt gcgctcgcct
      181 atgctgccgg cgacaaaacg gccagcggcg cgattaccac ggccttgagc gagctgaaca
      241 gttcgctgat ctggcttatc gtcgtcgcct ttatgattgc ccgtgggttt atcaaaaccg
      301 ggctgggtcg gcgtatcgcc ctacaaatga tccgtctgtt aggtaaacga acgctgggtc
      361 tggcttatgg cctggcgttt gccgatctga tcctctcccc cgcgatgccc agtaacaccg
      421 cgcgctgcgg cggcgtgatt tacccgatcg ccgactcgct ggcgcgcagc tttgattcac
      481 atccggaaga tgagtctcgc agcaaaatcg gcacctttct gatcacctgt attggcaatg
      541 ttaacgacgt caccgccgca ctgtttatga ccggttatac gggtaacctg ctggcggtaa
      601 aactggcggc gaacgccggc gttacgttga gctggggaag ctggtttatt gccgcgctct
      661 tgccttgcct ggtctctttt cttatcgtcc cgctgctggt ctactggctg acgcgtccgg
      721 aaattaaaca tacgccggat gcgccggatc tggcgcgcaa agagctggcg caaatgggca
      781 gtatggcgcg cggcgagtgg ctcatgctgg cgaccgtcgg tgtgttgctg gtgctatgga
      841 tttttggcag ctcgctcggc gtggatgcca cgacggcctc ttttgtcggt ctctctattt
      901 tattactgag cggcgtgctc acctgggaag acgttaaaag cgaaaaaggc gcctgggata
      961 cgttgatttg gtttgccgcg ctgctgatga tggctaacca gttgaaaaaa ctaggattca
     1021 ccagttggtt tggcaacctg attggcgaca gcatcggcag tacgatgcat ggaaccagtt
     1081 ggataatcat cctgctgctg cttaacgcag cctattttta tacccactat tttttcgcca
     1141 gcggcaacgc gcaaatcgcc gcgctgtatg cggtgtttct gggtgtcggc ctgcatctga
     1201 atataccggc ggcgccgatg gcgctcatgc tggcgtttac cagcagcctg tactgctctc
     1261 ttacacagta tacccacgca cgcggcccca ttctttttgg cgccggctat gtaccgacgg
     1321 gcatctggtg gcgaacggga tttattatca gcctctttaa ccaggcggtc tttttgacag
     1381 tcggcctcgc atggtggaaa gtgttagggt tgtattaaac gcttaacgca tcgataaccc
     1441 cctcggttaa cggagaaatg gaatgacctg cattttctgt caaatagttg aaggtaaagc
     1501 accttgtcat aaagtttggg aagatgagca tcacctggct tttttgtcga tttttccgaa
     1561 taccgatggg tttaccgtag tgatcccgaa aaaacattac cccagctacg cgttcgatct
     1621 accgccgcag gcgttagcgg acctgatgct ggcgacccaa aaagtggcga agaaactgga
     1681 taaggctttc ccggatgtca gtcgtacggg aatgttcttc gaaggtttcg gcgtagacca
     1741 tgtgcatagt aaattaagcc ccatgcacgg tactggcgat ttagcccact ggaaaccgat
     1801 tgaatcgcgg cagaataaat ttttcgaaca gtatgaagga tacctgtcgt cacacgatca
     1861 tgaacgggca gatgatgaga aactggccgc gctggcggcc agaattcgtg aggcataaat
     1921 acggagcact tctgccggat ggtgttcggc ctgggtcgat ctgtgggcct gataaacgca
     1981 gcgccatcag gcaaaataat tgctggatcg cggcttcgcc ttatccagcc tgacaggata
     2041 cctgtaaaac cgtttaacgc cccgcgcctt tcccgcgctt cttattagca gcaagcccct
     2101 gccgctgatg ttccaccggc gtatgcttgg tcaacgccgg gcgggtattg cggttctggc
     2161 gacgcgcttc gcgcatctct tcaatggtcg gcgcaggcac cagacactca cggcgaccgc
     2221 caatcaggtg ctttttgccc atcgcttcca gcgcctggcg aatcagcggc cagttcgccg
     2281 gatcgtgata acgcagcagc gccttatgca ggcgacgttg cctgtctccc ttcggcacca
     2341 ccacatcttc actcttataa ccaattttac ccagcgggtt tttgccggtg taatacatgg
     2401 tggtcgaatt tgccaacggc gacgggtaga agttctgcac ctgatccaga cggaagcggt
     2461 ggcgcttgag ccacagcgcc agattcacca tatcctcgtc ccgcgtgccc ggatgcgcgg
     2521 agataaaata tgggatcaga tactgctctt ttccggcctg tttagagtaa aggtcaaata
     2581 actctttaaa gcgatcgtag ctgcccatac ccggcttcat cattttcgac agcggacctt
     2641 cttcagtatg ctccggcgca atcttcagat agccgcccac atgatggctt gccagctctt
     2701 taatgtagcg aggatcttct acagcgatgt cgtagcgcac gccggaggca attaagattt
     2761 tcttaatgcc tttcagctca cgggcgcggc gataaagatt gatcgtcggc gtatggtcag
     2821 tatccatatg cggacagata tccggataga cgcatgacag gcgacgacag gtctgctccg
     2881 cacgcggcga cttacagcgc agcatataca tgttcgcggt aggaccgccc agatcggaga
     2941 tcacgccggt aaaccccggc accgtgtcgc ggatcgcttc gatctcgttg ataatagagt
     3001 cttccgagcg gctctgaatg atgcgccctt catgttcagt gatcgagcag aaagagcagc
     3061 cgccaaagca gccgcgcatg atattgatcg aaaagcggat catctcatag gccggaatac
     3121 gggcattgcc gtaagccggg tgcggcacac gctgatacgg cagcgcaaac acgctatcca
     3181 tctcttcagt ggagagcggt atggcgggcg ggttgatcca gacatagcgg tcgccgtgtt
     3241 tttgcatcaa cgcccgcgcg cagccagggt tagtttcgtg atgcagaata cgcgacgcat
     3301 gggcgtacag caccttgtcg cctttcacct tttcaaagga tggcaacagg atataggttt
     3361 tttcccacgg cttcggacgc ggcggctgca cggtaatcgc cttagcttct tgctttttcg
     3421 gcgcgaccgg cttgttatcc gcgcacggca gatcctcgcc atagggatgg ggaattggat
     3481 cgattttacc cggcgtgtcc agacgagtgg agtcgacgcc gctccagcct ggcagcgctt
     3541 ctttaaccat aatcgcagtg ttacgcacgt cgcgaatctg atcgatggtt tcgcccattg
     3601 ccagacggtg cgccacttcc accagcggac gctcaccgtt gccaaacatc agcatgtcgg
     3661 ctttggaatc gactaacact gaacgacgca cagtatcaga ccagtagtcg taatgcgcgg
     3721 tacggcgcag actggcctca atgccgccaa ggatcaccgg gacatctttc cacgcttctt
     3781 tgcaacgctg ggtatagacc agcgtggcgc ggtccgggcg tttgcccgcg acgttatccg
     3841 gggtgtaggc gtcatcgtgg cgcagcttac ggtcagcggt gtaacggttg atcatcgagt
     3901 ccatgttgcc agcggtgacg ccgaagaaca ggttcggttt acccagacgc ataaagtcgt
     3961 ctttgctgtt ccagtccggc tgggcgatga tccccacgcg gaagccctgc gcttccagca
     4021 tacggccgca aatcgccatg ccgaagctcg gatgatcgac atacgcgtcg cccgtcacca
     4081 gaatgatgtc gcagctatcc cagccaagtt gatccatctc ttcacgtgac atcggcaaaa
     4141 acggcgccgg cccaaaacag gcggcccagt actgcggcca ggagaaaagg tcgcgatccg
     4201 gttggatcag ggagatagcg ctcatattgc ttccaaaaaa ttggcaaaaa aataatcaaa
     4261 ggtcggggat tataagctgg aatggaagag aaatcgaatt gattggtgag gctgcactct
     4321 gtagcggggc cgattgcctg ccccgtcggt tatcgtactt atggacgagc aggcatatct
     4381 gctactttga taataggatt ttgttcttcg agcaaattca acagtaccgg cgtgacatga
     4441 tacatggatt ctgcaatcat gactttccct cgcagggtga ttttcttccc tataaaccgt
     4501 tgataataat tgtatttttc aggcggaaga atgagctgga catagcgatc ccagtcaggt
     4561 tggtccatca tggcccctgc cacacactga aggtttattg tttttaattc gagatcttta
     4621 tccgagtgtt ggccttgatt atcttcaatg acgtgctcgc gtttgaccat cataccttcc
     4681 agttcaatcg tgtcaccctc tttgttgcag gaagaatcaa agttcacata agcgagaaca
     4741 tatttccctt tcttttcatc aaactcaaaa gtggaattgt aataaatacc taaaggttcg
     4801 ctgtataaaa aggagtagcg cttatagctc tcgatatcgc gttgacagtt tccgccgcca
     4861 ttgatcatta agtctctgta tttttgccat actttttcta aattgattgg ctgatctgca
     4921 ccagtcgtaa ggtattctgc cgtattgtcc atgacatatt tgatattatt cgctttcagc
     4981 gcctcacaaa aatcggttgt gttctgaata tacagcgcct ttttacgctg tgactcagga
     5041 gaaagcagct ctttgaggag tttgatatta cgatgctctg tctcggtaat gaggtaatca
     5101 acgttcgcat agcgtgggcg ataccacggc tgctgtcgga agtaccgatc catctcaccg
     5161 cccggtctga aaatataacc gtgacgagca taaatctcat taagcataat tttaagatcg
     5221 gctatcgagg ttgcgctggt ttgcacgctt cttacctgaa gccaggtccg cgaggcttca
     5281 ggaaatcggc cttccagcgt gatgtgctct atctgcggtg caaaagcaag atagctgccg
     5341 taatccaaca gagttccctt cgtccccatg ggaatgagtc ctttcctttt aggcgtcacg
     5401 agaaaatcga tacagcgcgt atgctcactt ccagtaatca ccgaatggtc attctcttgt
     5461 tcaaaaaact ggatgtcaca ccacggcgcg ccactcatca tagaaaaatc gtcaggaaca
     5521 acgcgctgcc attttcgaac gtcgggcaac tcagcgtaaa acctgagcca ctcatctgca
     5581 gtggcggtat aatcatcgtt ttcgctgcca taaaagggtt cgcgactgtc accgaaaaag
     5641 ataaagtcat taagcgtgta gtctgtgacc ttgccctgaa aatagatttt tttattttcg
     5701 atctcagggc ggaattttag ttccgcatta gctgagaaga taaacaggca cataaatata
     5761 aataaaaaac attttttcat tatttaccac tccctgtatc tctcttaaca atcaatgtaa
     5821 ttttaattat cagagcacgg catatcagtc taaatcggcg cactgctgtg ctaattttat
     5881 acgcacattg gtacgccgcg tatcttctgg tggatacacc ttatcgatca ttgcgttaag
     5941 cttgttacag tccaaccagg ccatccggta ggcagtcatc aggctatgcc tttcatcctg
     6001 gtaatcaagg ctggctacaa taagggcttc cgacaacgcc gtatgttgct gttgcatact
     6061 ttgcagtatc cccgccagaa tatccggcgg cagcgcgtcc tctttcgagg ctgtatgcaa
     6121 tgtgcgtgaa atcaggaaat tccagccgtc cgtcaactta tcctgaggga tgtgctgcca
     6181 gttcagcatc tgccctttca ccaacgcacg cagcgtctcg ccatccgcat caataaacag
     6241 cgacgccagc agatttttat tcggatagac cgactgcccc agcacctgcg gcgtcagttt
     6301 tatctgggca agcagcgctt tagtttgccc ctgcaacaag aaataatatg cgcgatacag
     6361 cggattttgc gcttcacgcc gctgccagaa aaaggccagt gtctctttat cctgaagctg
     6421 tatcgccccc gaataggctt catcggtgag gagatcgggc atgacccgta gcagaatgtc
     6481 ggccatctca aaaaaagtct ggcgaaatcc ctcaggttta aaacggggcg tggggagata
     6541 ctccaacgga ttttgccgcc gtacgatggt gcgatttgcc tgcgcctgcg gggagtcgcc
     6601 catgagctgc tcgctaaaaa tacgcaccgc agtgatattg ccactctcaa aagcagcaaa
     6661 aaatggcgca ttgacgaaat agccatcttc ccgcgagaac ctaaaaggcg atgccacacg
     6721 tgcagtcaga tcgcgcaagt ttttttctga tatgcctggc gcttttaccg cctgaaccag
     6781 tgtctgttcc aacgtactgt tatcatgaat gctctctaac tgacgcaggt cgcctgcctg
     6841 aacctgcctg agcaactgcg caatattttg ctgttgccat tgatagctaa tagcacgcca
     6901 cagctccggc atcaccgggc acagcatccc aatgaacaca atatggcaca gtagccatgc
     6961 gggccacggc ttgcgcagcc aggttcccag cagcagcgcg ggcagcaagc ccgcccaact
     7021 cagaatcggc aacaggagca tcaacatcca taccgtgcct gtttgactca acaactgggt
     7081 gtactgcaac gtgggtaaca gcaataccac gaatgcccac tgtggtagta atacccacag
     7141 caaaatctgt cggctgcgtt ttttggaaaa catcaggatc agcagtgatg ccaccgcagc
     7201 ggcatacccc cacggtagaa cacaaaacat cagcagttca gagccaagcc atcgattaat
     7261 ataatccatt tactattcct ttagtcactt cgcgactgga cacagcgcat tcagcctttg
     7321 tcgcgtatcg tgtagtactt gttcgctccc cactactaaa gcattcaaca cctcacgcaa
     7381 ttgctcacag gaaagcccag cctgtaaaaa agcggcagga aacgtcggtg tccagggaag
     7441 atagtgggcg atttgctcgt tggataacgc tttctgcgct tgcatcgcct taatgatctg
     7501 tatcagcaat gcgttctcta atgctccacc acgcagtcgt aatatggcct gatgcagagg
     7561 ctcattattt ccgtcttcca ttgctcgttt ccagtccact acgtttgcat caataagcga
     7621 ctgaatcatt accagatcgc cattgctcag tatgaaagtg agtaggtttt cacgatccca
     7681 cctctcaatc ggcggtgtga tcaatatttc tggattatgg gttacctcgc ttattagcga
     7741 ttccgttttg gctaacaaca ccatcgcttc gagcctgcgc agaggaatag tgggagggtg
     7801 tttctgccaa aaataagcaa ccaactcagt gttacgttgg ataatgggat aaatatagac
     7861 agtatcattc aacagttctg gcataatatt cagcaatagc tgactaattt ctagtctgta
     7921 ctgctcgcga tactgtgata tatagttaga tttataaagc gtcagcagtg gattttcttt
     7981 acgagcaaca atattgcgat tctctctggc ggaagatgtc tcgcccacca gttgctggct
     8041 aaaaaagcgt actatcggta cgttatgttg gcgaagagcg gtagcaaatg gcgtataaag
     8101 aaattcggcg ttcgggatcg ccgcttcagg gcaagattct gccgctgtca aaaatggcga
     8161 aatacctcgt attttagcca gataacgcaa taaattttcc ggtgtatcgc ggtgttctgc
     8221 agccagcgtc aaaacacttg ccaattgata acaagatgca tcctgcaaaa cctgaacatc
     8281 ccccttcgcg cgctcaaaca gtcgggtaat tttatagtta tctcagtctt caccaatgtg
     8341 gtgccataat cgcgggccgt ccatcacata aacgaaaacg aacaaaaaaa tagtatggga
     8401 cacgatagtt cccagtataa aaaatggaga ctctcgacta gaaaaaatag caattattat
     8461 cgagggcagc aatcctgata tcaataaata tacgatataa atatcttttg aatcaatcca
     8521 gaataatcct ccccacacta cacagacaac gctcacctgc ggaagaacaa cacgcaagaa
     8581 aacccgccga tagcgcaaag aatcaaatgc gccgacaatt aacctcaata atacaacgcc
     8641 ataaataccc cacgcgctca tcaatattac tgaatcccac atcatccacg caaatgattc
     8701 acccataaag tatccttact ttccatgctc attactgagt tcaaattcct cgttcctatt
     8761 ttccgataac acagcgagct aaacgcacta ataactatag taaatacaat gattgtatat
     8821 attgcccggc acggaggata ttatcatcaa caacaaactc catccgtttc ccaaattcat
     8881 tattgcccgc tattttttct gatgataaaa cacatcaaat tcaaactgcc atgagaaagg
     8941 ttccggtttg ttgctattat caaaggcaac ggcttgtgca tacagttcgt ccgtcaataa
     9001 ttccggcacg acgctaatca aactggtaca aatatctcgc gccaaaagtt gttgttgcag
     9061 aaaagtttgt tcatcagccg tactatcatt aaaaacacga ttcagtaggt ccaataatgg
     9121 attgttttgt aagagctgat gccgatattg ctttgcctgt acagaatcgc caataaacca
     9181 ggaggcaaac gtcccaacag cagaacgatt aagccggtcg atggccaaaa ccaaccaaat
     9241 tttttcagtt ccgcccgcaa tatcaaaagg ggaaatgcgt tttgcgagat gctcaatccg
     9301 cctattcgtc ccccaatccc ctgcgttttg cggctgcatg gcttgcgaca tcaaatgatt
     9361 taaaaaaacg cggtcatcag tcgtatcgat ttttcgtaac agcgtttctt ccgccacctg
     9421 ctgtgcctga taggcatcgc gccgatgatg cctatcgaga atatccccca tgtgcgccaa
     9481 caacagcagc aatacgacca catagcaccc ggcccaaagg tggtgtggtt ggcgtaatcg
     9541 gtggctaaac agtagcgcca acaataaact aagccccagc atccaccctg cactaatcgg
     9601 aaagaaaagc gtttcatcat ccgcagcaaa ccatagcaaa agaaccagcg caatctatgg
     9661 caaagcaatc cacagcaaca cgcgacgagg cgtttggaac aaaaaagcca ggcaaataac
     9721 aacgaagagc agaataagat agccgcctgt agtaaacatc cagaacgtca gtagccgcca
     9781 tccctcttca ttgattctca tcgaatatcc ctggttcgcc tttacgacgc cggattcacc
     9841 agcatttgcc caatcgagcc gcgatcagcc atttccagcg tctggctgtt gaaatagaac
     9901 gggaagtgcg gccaggacgg ctgaccgtag tagaccagca attcgacttg cccatccacc
     9961 cagacggtat ctttccagcc tctatcttcc gggaacggca tagcgccgtt gacgttacga
    10021 atcaggaaag agacgccctc aatatggaac gactgcggca tatcggcgcg taccgtccag
    10081 cgctcccagg tgccttgttg ggcggtaata tcaatgcgat tcacatccca cagttggccg
    10141 ttaatccccg gatcgtcgcc aagactgatg tcccgactgc ggacaggcgc gccgctcatg
    10201 atctccgtcg gcaacagacg catcggcaga ttatcggtca ccagcggcag caatccggtt
    10261 ggccgtaacg tcagcaccag ggtcgaaacc agaatactgg aaggctcaaa gaaaccgcga
    10321 atccgatcga ctatgctggc cgcttccccg caggtgatcg agacttcgtc gccgttggtc
    10381 atatcaacca ggatttcacg tcgctcgccg ggcgccagtg acaactgttt gacggaaacc
    10441 ggcgcaggta aaaagccctg atcgcctgaa atcacatgca gcgcccggcc atcgctcatc
    10501 tgaagctgat agcgccgcga gttcgaggcg ttcaacaacc gtaaccgcac ccagccgcgg
    10561 gacacttcga cataggggct ttgcgcgccg ttcaccagca gcgtatcgcc gacaaaacca
    10621 ccgctgcccg gttcgctgta ctccggcgtc ccaaagttat ccagccgttt atcctggata
    10681 ataacgggaa aatcatccac gccgtaatgg ttcggaatgg gcagcgtttt actgatgtca
    10741 tcttcgacca gccacattcc ggccaggccg ttatacacct gctgcgcagt gcggttaggc
    10801 gtgttagcgt gataccacag cgtcgcggcg ctctgacgaa tcggcaacac cggcgcccag
    10861 tccgcgttcg gcgacatcat acgcgccggg ccacccatca gcggccccgg caccagtaaa
    10921 ccagcaaccg tcatggagac attttccgcc aggcggttgc tatagatgag tttaacgtca
    10981 tcgcctttcc agacgcggat tgtcggcccc agataacgac cgttcactcc ccagaccggc
    11041 gcgcgcgtgc cttgcgtaaa ggaccagtgc gctcgctgta gcgtcataaa caacggctgc
    11101 ccgcgacggg actccagcaa cggcggaaca ggcaacggct gttgctgacc ggcagcattc
    11161 gccctgaggg gaatcgcgcc tgcacatagt gcgattcccg atgcctgaag aaactgacgc
    11221 cgactgaatg acatataagc tccatgtaaa acaggctaaa gagttgtgcc tgaaaaaatg
    11281 atttctacaa taacagagta aggctgctta aaccttaccg gtcgcttcac gttccgcaac
    11341 ctctttatca agttccgcga ttttttgctc cattaacgca cggcagtggg ccgccagctc
    11401 acgaacctga tctttaccat attcgctgac gtcgactggc ggcagcattt ccacaataac
    11461 cagtccgttg ttcaggcggt ttagattgac tttgttagag gtgttggaaa cgcagacagg
    11521 aatgatcggc acaccagccg cgatagccgc atgaaacgcg ccggttttaa acggcagcag
    11581 accgcgtccc cggctacgcg taccttcagg gaacatccag atagaaatac ggcgcttttt
    11641 aaaatggtta actactgccg caatggtgct atgcgctttg gcgcggttat tacggtcaat
    11701 caacagatta ccggtcagcc agtacagttg cccaaaaaac gggatccaaa gcaggctttt
    11761 tttccccacc gtcaccgttg gcggctgcac aatattcgcc gccgtgacca tatcataatt
    11821 attctgatgg ttagcaatat agatagcatt gccatagttt tccgcatcgg cgggtttgcg
    11881 gcactccact ttcaggccaa acagcggggc cagacgaccg aacatatgtc caaacgtcgc
    11941 cacgtgtttt gggttacgtg ggctgaaaag gcagtaaata gaaccgaaaa cacagaccag
    12001 aatggagtaa ataacggtaa caataagacg aaaaatatat agcataacaa cctctgaagg
    12061 cctaagagcc cggcattcta cgtcacctga aattcaggtt aggattttgg taagtgtggc
    12121 tctctggaaa aacgtattgt taatcgcaat gcacgaataa acaacggttt tacgggaaat
    12181 tttaatgtta atccgatctg aaaccgtagg ccggataaga cgctactgcg tcgtcatccg
    12241 gcaacggcag agcgccggat ggcggcttag atgccttgtc cggcctacgg gcgcccctgt
    12301 cttactcttc gctgtcgcca tgacttacgc gatgcggcga atcaatctca atgcgatcga
    12361 tacgctgcag gccgcgcatt aatgtgccac ggcgtccgcg ttcaccgacc accttttgta
    12421 actcttcagg gcgcagtttg attttgcgct tcccgacatg gatagtcaga gtgctttgtg
    12481 gcggcagcac gtacaggtgc gccagtccat catcgccttt cgccgcttcc gcagagggga
    12541 tattaatgat cttattgcct ttgcctttcg acagctgcgg cagagagtct accgggaaca
    12601 tcaacatccg tccggcctgg gtaatcgcca gcagcatatc gtgctcgtct ttaatcacca
    12661 gcggcggcat gacgtgcgca ttttccggca gtgtaatcaa cgtcttaccg gcacggttac
    12721 gggcaaccag atcgttaaac gtacaaacga agccgtagcc cgcatccgac gccatcagca
    12781 gtttctggtc atcgccttcc atcagcatat gctctacggt cgcccccggc ggcagcgtga
    12841 gtttgccggt cagcggctcg ccctgcccac gcgccgaggg aagcgtaatg ggatcaatag
    12901 catagctgcg cccggtggta tcaataaaca ccaccggttg attgctctta cctttcaccg
    12961 cggctttaaa gctgtcgccc gctttatagt taagccccgg cgcatcaata tcatgacctt
    13021 tggcgctgcg cacccagccc atctgcgaca gcacgatagt caccggttcg gacggcagca
    13081 tatcgtgttc gctcatcgct ttagcttctt cgcgctcacg cagcggagaa cggcgatcgt
    13141 cgccataggc atcggaatct gcctgtagct cttttttcag caaggtattc attttgcgtt
    13201 cggacgcgag aatgccctgc aactggtcac gctctttttc cagctcgtcc tgctcaccgc
    13261 gaattttcat ctcttccagt ttggcgagat gacgcagttt cagttcgaga atcgcttccg
    13321 cctgggtttc gctgatgccg aaacgcgaca tcagcgcggg tttcggctca tcctcgttac
    13381 ggataatctc gatcacttca tcgatgttga gaaacgccac cagcaaacct tcgaggatat
    13441 gcaggcgctt aagcactttc tccagacgat agttcagacg acggcgcacc gtgtcgcggc
    13501 ggaacgccag ccactcggtg aggatctcca gcaggttttt caccgccgga cgaccatcca
    13561 gaccgatcat gttcaggtta atacggtagc ttttttccag atcggtggtg gcgaacagat
    13621 ggttcatcac ctgttccata tccacacggt tggagcgtgg cacaatcact aaacgcgtcg
    13681 ggttttcgtg atccgattca tcgcgcaggt cgtccaccat cggcagtttt ttattgcgca
    13741 tctgcgcagc aatctgctcc agcacttttg cgccagatac ctgatgcggc aacgcggtga
    13801 tcaccacggc gccgtcttct ttggtccata ccgcgcgcat acgcacggag ccacgcccat
    13861 tttcgtaaat tttacgaatt tccgcacgag ggataatgat ctccgcttcg gtcgggtaat
    13921 ccggcccctg gacgatatcc agcaactgat ccagcgtcgt tttcggctgc tcaatcagcg
    13981 taatcgccgc tttcgcgact tcgcgcaggt tatgcggcgg aatatctgtt gccatgccca
    14041 ccgcaatacc ggtggtgccg ttcagcagga tgttcggcag acgcgccggt aacattttcg
    14101 gttcctgcat ggtgccgtcg aagtttggca cccagtccgc agtcccctga ccgagttcgc
    14161 ttaacagcag ctcggcgtat ttggacaggc gggattcggt ataacgcatc gccgcgaatg
    14221 acttcggatc atccggcgcg ccccaattcc cctggccatc gaccagcggg taacggtaag
    14281 agaacggctg cgccatcagc accatggctt catagcaggc gctgtcgcca tgcgggtgat
    14341 acttacccag tacgtcgcca acggtacggg cggatttttt aaatttagcg gtggcgttca
    14401 gccccagctc tgacatcgca tagacgatgc ggcgctgtac cggcttcagg ccgtcgccaa
    14461 taaacggcaa cgcacgatcc atgatcacgt acatggagta gtttaagtag gcgttttccg
    14521 taaattcatg tagcgcaagg cgctctgcca tatcgctcat taacagggga tcctcaatct
    14581 gcatgctgac cgttcggacg gcaatattgc cgcagataat accctatctc acggtctgag
    14641 tcacaaaccg tgagacaggt tgcgaggaag ttaacgaagc ggcagataga tatccgtcag
    14701 cagctcatgt tccgccacct catggacgaa attcaggtac tggaagaaga ccggaaaatc
    14761 gcgcagcgtc tcgccgctgg ccggtagcca ttcgcggaat aaataccaca cgctctccgg
    14821 gaggctgtcg agcgatccct gatggcgcac caccgcgcag cgcccgccag gaatctcgct
    14881 attcaccacg ccaacgtcat tttcggctat cggctggcgg acgctgccgc agatatcaaa
    14941 gcggaattga gccggcggcg tcgtctgcgg gtcgtgccag gcaataccaa aagtttgact
    15001 gctggcaatc ggcgactggc ccgtttcgcg tcgccatgca ataaatttcg ccgcgctggc
    15061 gttgacctta tccggatgcc ccagatgcgt cagcatcgcg acgcgggtag gaggaaattc
    15121 aacgattttt acgtccatga catgctgctc ctgtaacgca agtttaggaa cgcgttggtg
    15181 ccaggccagc cagtccggcg attgccgaaa ccggcacggg ctttgaccaa acgcggtttt
    15241 gaaagcacgt gtgaacgact ccggattctg aaatccggca tccagcgcga tatcgataac
    15301 tttatcttgc ggattaaacg ccagccgcca tgacgcccgg cgcaaacgca gccactggat
    15361 atagcgatag agcggaagcc cgctccagac ggtaaactgc cggtgaaaat gaaacggcga
    15421 gctgtgcgcc atccggctta acgcctcaag cgacagaggc tcatccagat gacgctcaat
    15481 gtggtcgcaa acgcgccgca gacgttcgga ataagccgcg ctgatcaggt cattcatcac
    15541 tgcctccttg tggcctattc tgcccaccgg gcggctgtga atcctgaccg atcttgcgca
    15601 atgtgggatt acggattcac tttacgaatc tgtttcacgt cgatttcgac agagttccag
    15661 tctttatcca cttcaccctg aatttcaacg gtatcctgcg gggttacggt caggccgttc
    15721 cagcgcttgt ggtcaatgtc cacattgata gtaccggtcg catctttaaa cacatacagg
    15781 tcgtcggaaa tgcgctcgac gatattcccg cgcagcgtta cccacgcatc gtcacgcagc
    15841 gatttagcgc tctctaccgt cgtgctgctg ccgttcgggc cgacaaatcc gccgccctgc
    15901 gtttgcgtcg ccgacgggcc ggagaaaccg ccctgctgag ccgccagaac cggggtagaa
    15961 cacagtgcca taacggcaac gattgcagct aattttttca tgattacttt tccctttcat
    16021 gtcgtttcag atccatttaa taaggtaatc cttaacaact tcttaaggca aaaaaagatt
    16081 ctttttttct gtacatcgcc tgcggcgaca aggttaactg acggcaacgc gagttaccgc
    16141 agggaagaac agatgcgaat tttactggta gaagatgaca cacttattgg cgatggcata
    16201 aaagcaggtc tgagtaaaat gggtttcagc gtcgactggt ttaccgaggg acgtccgggc
    16261 aaagaggcgc tttacagcgc gccttatgat gcggtcattt tagatttaac gctgccagga
    16321 atggacggac gggatatttt gcgcgaatgg cgcgaaaagg gtaaacagga accagtactg
    16381 atcctgacgg cgcgcgacgc gttagcagag cgcgtcgagg ggctacgtct gggcgccgat
    16441 gactatttat gtaaaccttt cgcgctcatt gaggtcgccg cccgtctgga ggcgctggta
    16501 cgccgcgcca gcggtcaggc cagtagcgaa ttgcgccacg gccaggtgac gctcaatcca
    16561 ggcaatctcg tcgcgacgct tgccggcgaa ccgctggccc taaaaccaaa agagttcgcg
    16621 ttgctggaac tcttactgcg caacaaaggt cgcgtgctac cgcgcaagct tattgaagag
    16681 aagctgtata actgggatga cgacgtgtcc agcaatgcag tggaagtcca tgttcatcat
    16741 ttacgccgca agctcggcag cgaatttatt cgcaccgtac acggcatcgg ctacaccctg
    16801 ggtgacgcat gaaattgacg caacgtctca gcctgcgcgt caggctgacg cttattttcc
    16861 tgattctggt ctccatcacc tgggcaattt ccagttttgt ggcctggaga aagacgacgg
    16921 ataatgtcga tgagctgttt gacacacagt tgatgttgtt cgccagacgg cttagcaccc
    16981 tcgatcttaa cgagctcaac gccccgcagc gcatggcgca tacgccaaag aaattaaaac
    17041 atgggcatat cgatgacgat gcgctggcgt tcgccatctt ttccgctgac ggcaaaatgt
    17101 tgctgcatga tggcgacaac ggccaggata ttccgtatcg ctatcgccgg gaaggtttcg
    17161 acaatggcta tctgaaggat gacaacgacc tctggcgttt tttgtggttg aactcggcgg
    17221 acggcaagta tcgtatcgtc gtcggtcagg agtgggatta ccgcgaagat atggcgctgg
    17281 cgatcgtggc ggcgcaatta acgccgtggc tgatcgccct tcccttcatg ctgctgattt
    17341 tattactcct gcttcaccgc gagctcagac cgttgaaaaa actggcgcag gcgctgcgct
    17401 tccggtcgcc ggaatcggaa acgccgctcg acgccaaagg cgtaccgagc gaggttcgcc
    17461 cactggtcga agcgcttaat cagcttttta gccgcatcca ctccatgatg gtgcgcgaac
    17521 ggcgatttac ctccgacgcc gcccatgaat tgcgcagccc gctggccgcg ctgaaagtac
    17581 aaaccgaggt ggcgcagctc tcgggcgacg atccgctatc gcgtgataaa gcgctgaccc
    17641 agctccatgc ggggatcgat cgcgccacgc ggctggtcga tcagctactg acgttatcgc
    17701 gtctcgactc gctcaataat ttgcaggatg tagcggagat ttcgctggaa gagctgctgc
    17761 agtccgcggt aatggatatt tatcatccgg cgcagcaggc gaatatcgac gtgcgtttac
    17821 agcttaacgc ccatgacgtc atacgtaccg gccagccgct actcttaagc ctgttagtgc
    17881 gtaacctgct ggataatgcg attcgctaca gtccgcaggg cagcgtcgtc gacgttacct
    17941 tacatgcccg cagcttcacc gtcagagata atggccccgg cgtagcgcca gagattctaa
    18001 cgcatatcgg cgagcgtttt taccgcccgc caggccaaag tgtgaccggc agcggtctgg
    18061 gattatcaat cgtccgccgc atcgctacgc tgcacggcat gacggtgtcg tttggcaacg
    18121 ccgcggaagg tggatttgag gccgtagtac gctggtagca gagatttttg ccaaaaacgc
    18181 aaaagacttt gcacattttg ctaatttcac cgcaccgccc gtcagcgtag aatcagcagc
    18241 aaacgcattt cttgaggaca caaaatgagt aacatcctga ttatcaacgg ggcgaaaaaa
    18301 ttcgcgcact ccaacggcca gttgaatgac accctgaccg aagttgccga tgggctgctg
    18361 cgcgatctgg gtcatcaggt taagatcgtc cgcgccgaca gcgactatga cattaaagaa
    18421 gaggtgcaga atttcgtctg ggctgacgtg gtgatttggc agatgccagg ctggtggatg
    18481 ggcgcgccat ggacagtaaa aaatatatgg atgatgtctt taccgaaggt cacggcacgc
    18541 tctatgccag cgatggccgc acgcgttccg atgccgctaa aaagtacggt tccggcggtc
    18601 tggtgcaggg gaaaaaatat atgctgtcac tgacgtggaa cgcgccgatg gaagcattta
    18661 ccgaaaaaga tcagtttttc cacggcgtag gcgtagatgg cgtctatctg ccattccata
    18721 aagccaacca gttcctgggc atggacgcgc tgccaacgtt tattgccaac gacgtgatta
    18781 aaatgccgga tgttccgcgc tataccgcag aatatcgcaa gcatcttagc gaaatttttg
    18841 cttaactggt catcctggaa ttagaaggag ttaaccatgc ttaccgtcat tgccgaaatt
    18901 cgcacgcgtc cgggccaaca tcaccgtcag gccgtcctcg atcagtttgc gaaaattatt
    18961 ccaaccgttc ttaaagaaga ggggtgccac ggttacgcgc cgatggtgga tcatgccgcg
    19021 ggcgtgagtt ttcagactct ggcgcctgac tcgatcgtga tgattgaaca gtgggaaagc
    19081 gttgcgcacc ttgaagcgca tctgcaaacc ccgcatatga aagcctatag cgacgcggta
    19141 aaagacgatg tgctggaaat gaatattcgt attctggaat ccggcgttta agttattacc
    19201 ctcgtctgac gtcgccctga tgcgatgcgc aagtgtcgcc atcaggctgc gacgtcatgt
    19261 cggattctct tatccggcct gcggcgcgca gaccggataa agcgtgcaac aatcgttaca
    19321 cgtcgagatc cgcgagatcg cctttttcct gtagccagtt gcgtcgatct tcagaacgtt
    19381 tcttcgccag cagcatatcc atcatcgcat tagtacgctg atcgtcttca tcgctaatgg
    19441 tgagctgcac caggcggcga gtattcggat caagcgtggt ttcgcgtaac tgcatcgggt
    19501 tcatttcacc caggcctttg aaacgctgga cgttcggctt gcctttctta cgcttcagtt
    19561 gttccagtac gcccgccttc tcttcttccg tcagcgcgta atagacctct ttacccaaat
    19621 cgatacggta tagcggcggt agcgcgacgt agacatgacc attcttcacc agcgcgcgga
    19681 agtgtctgac aaacagcgcg caaagcagag tagcgatatg caaaccatcg gagtccgcat
    19741 ccgccaggat acagatcttg ccgtagcgca gctgactcag atcgtcgctg tccggatcga
    19801 taccgatcgc cacggaaata tcatgcacct cttgcgaggc cagcacttca tcggaagaga
    19861 cttcccaggt gttaaggatc ttacctttga gcggcatgat cgcctgatat tcgcgatcgc
    19921 gcgcctgctt ggcggaaccg cctgccgaat ccccttccac aaggaacagc tcggttcgat
    19981 taagatcctg cgcggtacag tccgccagtt tccccggcaa cgccggaccg ctggtgagtt
    20041 ttttgcgtac cacttttttt gcggcgcgca gtcgccgctg cgcgctggca atcgccatct
    20101 ctgccagttg ttccgccgcc tgcacgttct ggttcagcca caggctgaag gcatctttca
    20161 ccacgccgga aacaaatgcc gcacattgac gcgacgacag acgctctttg gtctgcccgg
    20221 caaattgcgg gtcctgcatt ttcacggaga gcacataagc gcagcgatcc cagatatctt
    20281 ccgccgacag tttgacgccg cgcggcagaa tattgcggta ttcgcaaaat tcgcgcatcg
    20341 cgtcgagcag gccctggcgc agaccgttga cgtgcgtccc cccctgcatg gtcgggatca
    20401 ggttgacgta gctttccgtc agtaattcgc cgccttccgg cagccacaat agcgcccagt
    20461 caaccgcttc cgtttcaccg ttaaaattac cgataaacgg cttttccggc agcgtcggca
    20521 ggccgtttac cgcttcgccc agatagtcgt tcagaccatc ctggtagcac cagcgctgct
    20581 cgctgttatt cacttcatct ttaaaagtga tttccacgcc gggacacagc accgcttttg
    20641 ctttcagaac gtgcattaag cgagagacag aaaaacgcgg gctgtcgaag aaactttcgt
    20701 ccggccagaa atggacgctg gtgccagtat tacgtttacc gcaggtgccg acaacctgca
    20761 aatcctgcac tttttcgccg ttttcaaacg cgatgttata gacctgaccg tcgcggcgca
    20821 cggtcacttc cacgcgcttt gacagggcat tcacgaccga aatccccacc ccatgcagac
    20881 caccagagaa ctgatagttc ttattggaga atttaccgcc ggcatgaagc cgacagagga
    20941 tcagttctac cgccggaacc ccctcttccg gatggatatc caccggcatc ccgcgtccgt
    21001 cgtcaatcac ttccagcgat tgatcggcat gtaaaatgac atccacgcgt ttggcgtgac
    21061 ctgccagtgc ttcatccaca ctattatcaa ttacttcctg acccaaatgg ttggggcggg
    21121 tcgtatcggt gtacatcccc gggcggcggc gtaccggctc aagcccagtg agtacctcaa
    21181 tggcatcagc gttataagtt tgcgtcatgg tttaattagc aattcgaatt gattgtcagc
    21241 aactgtgcag tccaagaaaa tcgacaatct ggttgaaata atcttcgaag cccgtgaatg
    21301 cgtgattacc cccctcggtc actgtctgac ggcaggaggc gtaatatgcc accgcctggc
    21361 ggtaatccag cacttcatcg cccgtctgtt gcagtagcca gatcaggtcc ggcgcttcca
    21421 gcgggtcaat ctgcatgact ttaagatcat aaatatggcg agactctagc acatattgct
    21481 gcccggtgta ggggttctcg ttctgaccga gatagtcggt cagtaattca aagggccgca
    21541 cggcgggatt caccaccaca gccggcagca taaaacattg cgacagccag gtggcgtaat
    21601 aaccacccag cgacgatcct accagcccta atggcgcacc gccatgctca agtacgagag
    21661 attccagcaa ctccgccgca tcggcaggat acggcggcag ttgagggacg atcatctcaa
    21721 catgcggatg acgctccgcc agccagtttt ttagctggca cgcttttgcc gagcgagggg
    21781 aactgttgaa tccgtgcaaa tagagaagcg tagacatcag tatccttccg aagcggtatc
    21841 gggtcggaac cgggtatcct gcaggcgatg cacttccgtc tccaggacgc cgttcgcctg
    21901 gagctccagc gtacgccagc ccggcgcgat agtatccagc gtaaagttcg cgcagtgcgg
    21961 tttgaactgt acgcaggttg acggcgacgc caacagacgg cgaccgttcc agtcgagatc
    22021 cagctcctgg tgaatatgtc cgcatagcag atactttaca cgcgggaaat tcgccagcac
    22081 gctatccagc tcaccagcat tacgcaagct gtgctgatcc agccaactgc accctgccgg
    22141 caacggatgg tggtgcaaca ggagcaatgt ctgtctctct ggcgcatcgg cgagcttacg
    22201 ctcaagccat tccagttgga actcgctcag ttcgccatgc gggacgccaa acacctggct
    22261 atccagcaac aaaatctgcc attgttcacc gattaacacg cgtttagccg gggaaatccc
    22321 cgcctcttgc agcgcgctgt acattgccgg ctgaaaatcg tgattgcccg gtagccaaac
    22381 gcaaggcgcg cgaaagcttg cgataccctc agcaaaatgc tgataagccg cagcggattg
    22441 atcctgcgcc agatcgccgg tcgccacgat cagatcatat tcatactgtt gcgcccgaat
    22501 agcctccagc acggcctggt aactttccca ggtattgacg cctaacagcg tttcatgctt
    22561 ttcggcaaac aggtgagtat ctgtaatttg taaaatcctg actcgggcct caccagccag
    22621 aggtagggtt aacaggcttt ccaaatggtg tccttaggtt tcacgacgct aataaaccgg
    22681 aatcgccatc gctccatgtg ctaaacagaa tcgtagccag tcggccagaa actgattaat
    22741 ttgatgcttt tcgtcgcgtt gatgcaactt tttatttgga taatcatacc gcgctttgaa
    22801 gcgaaagatc tgctggcttg aacacacttc agccaccatc gcatcatggt agaggcgcac
    22861 cgtcagcgac ggcaggctcc agtaggtgat ggctggcgcc gtttgctcga tcgttacaag
    22921 cgtagtgtat cgggtcaatt ccacaatcgt taaccgatat tgtacgttgc ccacctgata
    22981 gctcaccgtt tcaccggggg cgtcattgcg cggcagcagg cggcgcaatt gcgaaaaatt
    23041 ggtttcgcac aaacgcatca tttctgggaa gtcaggtgta taacgcttca ttttttccac
    23101 tcgtttttta actcttgatg atgcaactga agccattgca aagcgatgac tgcggctgcg
    23161 ttgtcgattt tcccctcttc tacccactgg tatgcctgtt cccggcttac cacatgaacc
    23221 cgaatatctt cgttttcatc cgccagacca tgaataccta ccgcggtcgt ggcgtccact
    23281 tcacccacca gaatagatga gcgctcgctg gttcctcctg gactcgccag gtaactgatg
    23341 accggtcggg tgcggcctac ggtcagcccc gcttcttcca tcgcctcccg ccgggcgacc
    23401 gcctcaatgg tttcgccttc ttctatcatg ccggcgacca tctccagcag ccacggcgta
    23461 acgcttgtgt catatgcggc aatacgaatc tgttcgacca gcaccacctc gtcgcgttca
    23521 gggtcaaagg gtagcaagac ggcggcgtgc ccgcgctcaa aaatttcgcg ctttacctcg
    23581 ccactcattt ctccgttgaa taaacgatgg cggaatcgat acacatccaa tgaaaaaaaa
    23641 ccgcgatagc gcgtttcccg tgcaataatt tctacatcgc ttttggtgaa agtaactggc
    23701 aagttgtctg atttacgcat tgtgctgccc tgctagcaat aatgattaaa tgatgaattt
    23761 caagggtggt tgactgctgt tttatcaccc ttgtggtaaa ttggtgccaa ttaaggctcg
    23821 tatggcacgt aacgccaact ttttgcagtg gcggattctg ctagaatcag caattatttt
    23881 tacaaattga tcagcgctaa atactgcttc acaacaagga atgcaaatga agaaattgct
    23941 ccccatcctt atcggcctga gcctgtcggg gttcagcaca ctaagccagg cagagaacct
    24001 gatgcaagtt tatcagcaag cacgcctgag caacccggaa ttgcgtaaat ccgctgccga
    24061 tcgcgatgct gcattcgaaa aaattaacga agcacgtagt cctttactgc cgcaactggg
    24121 tttaggtgcc gactacacct acagcaacgg ttatcgcgat gcgaacggta tcaactccaa
    24181 tgaaaccagc gcttctctgc aattaacgca gacgctattt gatatgtcga aatggcgtgg
    24241 gctcaccctg caagaaaaag cagcaggcat tcaggatgtc acctatcaga ccgatcagca
    24301 gacgctgatc ctcaataccg cgaacgcgta ttttaaggta ttgaacgcta ttgatgtgct
    24361 ttcctatacc caggcgcaaa aagaggctat ctaccgtcag ttagatcaaa cgacgcaacg
    24421 ttttaacgtg ggtctggtcg ccattaccga cgtgcaaaac gcccgtgcgc aatatgatac
    24481 cgtactggcg aatgaagtga ccgcccgcaa caacctggat aacgcggtag aagagctgcg
    24541 ccaggtaacc ggcaattatt acccggagct ggcgtcgctt aacgtcgagc attttaaaac
    24601 cgacaaaccc aaagctgtta atgcgctgct gaaggaagcg gaaaaccgta acctgtcgct
    24661 gttgcaggcg cgtttaagtc aggatctggc gcgcgagcaa atccgtcagg cgcaggatgg
    24721 tcatctgccg acgctgaatt taacggcctc aaccggcatt tctgatacct cttatagcgg
    24781 ttctaaaacc aactccgccc agtacgacga tagcaacatg gggcagaata aaatcggcct
    24841 gaacttctcc ctgccgctgt atcaaggcgg gatggttaac tcgcaggtaa aacaggcgca
    24901 gtataacttc gtcggcgcaa gcgaacagct ggaaagcgcg caccgtagcg tggtgcagac
    24961 cgtacgttct tcctttaaca atattaacgc ctccatcagc agcatcaacg cgtataaaca
    25021 ggcagtcgtt tccgcgcaaa gttctttgga tgcaatggaa gccggttact cggtcggtac
    25081 acgtaccatt gttgacgtac tggatgccac caccactctg tatgatgcca agcagcaact
    25141 ggccaacgcg cgttatacct atttgattaa tcagttaaat atcaaatatg cgctcggtac
    25201 gctgaacgag caggatctgc tcgcgcttaa cagtacgttg ggtaaaccta tcccgacgtc
    25261 gccggaaagc gtagcgccgg aaacgccaga gcaggatgct gccgcagacg gttataatgc
    25321 ccatagcgcc gcgccggcag tacagccgac cgccgctcgc gccaacagca ataacggcaa
    25381 tccattccgg cattgataag ttattcgctg gcgctgcgtt tatcagacct atgcccttgt
    25441 aggtctggta agcgcggcgc tacctgtcat aaagccgcgc ctgaacgtaa gacaacgtaa
    25501 agatcctgct attccgccgc attctcgcct tttctcgctt caatttcgac cagtcatcct
    25561 ctattctgaa cgcatgttgt atttaccact gggtcctgga agacaaatat gaaacggaca
    25621 aaatccatcc atcacgcatc atttcgcaaa agctggagcg cgcggcattt aacgccggtc
    25681 gccctggcgg ttacggctgt ttttatgctg gctggctgtg aaaaaagcga tgaaaccgta
    25741 tcgctgtatc aaaacgctga tgactgttca gcggcgaatc cgggcaaaag cgcggaatgt
    25801 acaaccgcgt ataacaatgc gctgaaagag gccgaacgta ctgcgcctaa gtacgctaca
    25861 cgcgaagatt gcgtcgctga gtttggcgaa ggccagtgcc agcaagcgcc cgcacaggct
    25921 ggcatggcgc cggaaaatca ggcgcaggcc caacaatcca gcggcagttt ctggatgccg
    25981 cttatggcag gttacatgat ggggcgtctg atgggcggcg gcgcaggctt tgcgcaacag
    26041 ccgctgttta gctcgaaaaa cccggccagc cctgcatacg gcaaatatac cgatgcggca
    26101 ggtaaaaact acggggcggc gcaaccgggc cggacaatga ccgtaccgaa aaccgcgatg
    26161 gcgccgaaac ctgccaccac aacaaccgtt acccgcggcg gttttggcga atccgtcgcc
    26221 aaacagagca ctatgcagcg tagcgctgcc ggtacttcaa cacgttcgat gggcggctga
    26281 tacgcatgga aagagtcagt attaccgagc gcccggactg gcgcgataaa gcgactgaat
    26341 acgggtttaa ttttcacact atgtatggtg aaccgtactg gtgtgaagac gcttattaca
    26401 agttaacgct cgcccaggtg gaaaaactgg aagacgttac cgccgagctg caccagatgt
    26461 gcctcaaggt agtagaacgc gtcatcgcca gcgatgagct gatgacgaag tttcgtattc
    26521 caaaacatac ctggggtttt gttcgccagt cctggcaaac gcaacaaccg tcactctatt
    26581 cccgcctcga tttggcctgg gacggcatcg gcgagcctaa gctgctcgaa aataatgccg
    26641 acacgccaac atcgctgtat gaagcggcgt tttttcagtg gatttggctg gaagatcaga
    26701 tcaacgcggg caatctgccg gaaggcagcg atcagtttaa tagcctgcag gaaaagctga
    26761 ttgaacgctt tgctgaactt cgcgaacagt acggttttca gttgctgcat ctcacctgct
    26821 gtcgcgatac ggttgaggat cgcggcacca ttcagtattt acaggattgc gcggccgaag
    26881 cggaaatcgc caccgaattt ctctatatcg acgatattgg tctgggggaa aaaggtcaat
    26941 ttacggatct gcaggatcag gtcattgcga acctgttcaa gctctatccg tgggaattta
    27001 tgctacgcga gatgttttcc accaagctgg aagatgccgg cgtgcgctgg ctggaaccgg
    27061 cctggaaaag cattatctcc aataaagcgt tattgccgct gttgtgggag atgttcccgg
    27121 accatccgaa tctgttgcct gcgtatttcg ccgaagacga acatccgcca atggataaat
    27181 atgtcgtgaa accgatcttc tcccgcgaag gggcgaacgt atcgattatt gagaacggta
    27241 aaacgatcga atccgtggaa ggcccgtatg gcgaagaggg tatgatcgtg caacagttct
    27301 atccgctgcc aaaattcggc gacagttaca ccctgattgg tagctggctg attaacgatc
    27361 aacccgccgg aattggtatc cgtgaagatc gggcactgat cacccaggat ctctcccgct
    27421 tctatccgca tatttttgtc gaaggataga ttttcctgta agcccgatgc gcgtagcgcc
    27481 atcgggcaat cattcagcgc cttatccggc ctaccccacc tgcaccgaca acatacttat
    27541 actgcccatc tcaataccgt cgaccgggat ggtgataggt tccttgccgt cccaggcgcc
    27601 aagtacatac agcaaaggca aaaagtgctc cggcgtcggg ttcgataagg cgcccccttc
    27661 atgttgcaga taattcacca gcgggtgctg ttctaccggc ccctgccacg tcaggttagc
    27721 tttcacaaag tcattaaatg acgccgccca gggatacggt atattgtcac cgtgccaacg
    27781 cacagtccgc aggttatgaa ccacattccc gctagccacc agcatcacgc cttcgtcacg
    27841 cagcgtcgcc agtttacgac ccatctcaaa atgccatgcc gccggtttgg tactatcaac
    27901 actaagctgc accatcggga tatccgcatt cgggtacatc ttgatcaata cgccccagga
    27961 gccgtgatca aatccccacg cctctttatc gagcgcgacg ggaacgggag ccaacagttc
    28021 aaccagacgc tgcgccagcg caggcgatcc aggggccgga taatgcatgt catacagcgc
    28081 ctgcggaaaa ccgccaaaat cgtggagagt ttgcggcctt tccatcgctg tgacgcccgt
    28141 cccacgggta taccagtgcg ccgacaccac cactatcgcc tgtggtcgcg gtagggcttc
    28201 ccccaatcgc cgccaggcgc gggtataatc attatcgtcc agcacgttca tcgggctgcc
    28261 atgccccaaa aacaatgctg gcatacacgt taaagacatg atgttatcct tacaggaaag
    28321 acattttgtt aacatcacca tacgctttct tcacagagga agaactcaga taactatgat
    28381 gaagatcatc agttattttg aaggtcaggt tcggacggca aattgataag gagtaatgga
    28441 tgtcagtacc acttattctg accttactgg cgggcgctgc cacctttatt ggcgcgtttc
    28501 ttggcgttct tggccaaaaa ccgtctaacc gcgtgctggc tttttcgctg ggcttcgccg
    28561 cagggatcat gctgctcatc tcgctgatgg agatgctgcc cgccgcgtta gataccgagg
    28621 ggatgtcgcc tgtactgggc tacgggatgt ttattatcgg cctgttgggc tacttcgggc
    28681 tggatcgtct gcttcctcac gctcatccgc aggatctggt gcaaaaaagg cagcagccgc
    28741 ttcccggctc gataaaacgc actgcgattt tattgacgct cggcattagc ctgcacaact
    28801 ttccggaagg aatcgccacc tttgtcactg ccagcagcaa tcttgaactg ggtttcggca
    28861 tcgcactggc ggtggcgttg cacaatattc ctgaagggct ggcggttgcc ggcccggttt
    28921 atgccgcgac gggctcaaaa cgtaccgcga ttttttgggc cggtatctcc ggcatggcgg
    28981 aaattcttgg cggcgtgctg gcgtggctga ttttgggcag cctggtttca ccgatcgtta
    29041 tggcggctat catggcagca gtcgccggca ttatggtggc gctctccgtc gatgaactga
    29101 tgccgttggc aaaagagatc gatcctaaca ataaccccag ctatggtgtg ctttgcggta
    29161 tgtccatcat ggggctcagt ctcgtcattt tgcagacgat aggtatcggt taagagcaac
    29221 gtcgcgccgg atgcaggcct ttagccaggc aacatccggc tgcccgtcaa ggatatgcgc
    29281 tatttctgct cattcatcac gctgtcgcct tcgctcgtct ggcgaaaacg tttcgttcgc
    29341 gcttcaagta atgcatctct gtcttgccga aacgctctgc aataacgctt catatggcaa
    29401 atatacccta ctaccaccag a
//
LOCUS       DAJVKX010000048        29327 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000048 DAJVKX010000000
VERSION     DAJVKX010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29327
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.048"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(563..754)
                     /locus_tag="OPY25_002155"
     CDS             complement(563..754)
                     /locus_tag="OPY25_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2767 family protein"
                     /protein_id="HCS0927765.1"
                     /translation="MDEEKQAVFDDVCRVIGRAVVMLKETNQPVTKNSINLMLQAHSD
                     QSDDAYLSRIYAVAKDVME"
     gene            complement(863..1297)
                     /locus_tag="OPY25_002156"
     CDS             complement(863..1297)
                     /locus_tag="OPY25_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927766.1"
                     /translation="MYYSENEKIEKKRQKIANKNKQTSVKKGDLFYCRMTLNQSGGPV
                     DTSRMRVRVKDNVDSVGFLFPDDKQIISPKLEVVDSDSGERYGRAADGSITVSASYDG
                     HAYEIQIFNTLPVSQFNGAVVTHTSALEFAGSIDVFDCKKVK"
     gene            complement(1653..2246)
                     /locus_tag="OPY25_002157"
     CDS             complement(1653..2246)
                     /locus_tag="OPY25_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015405997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCS0927767.1"
                     /translation="MTFKMSDTPQTIKIFNLRSDTNEFIGAGDAYIPPHTGLPANCTN
                     IAPPDIPASHIAVFDAETQTWSLHEDHRGEMVYDTTTGNQVYISEPGPLPENVTSVSP
                     GGEYQKWDGKAWVKDEAAETAVRLREAEGTKSRLLQMASGKIAPLQDAVDLGLATDEE
                     KSQLAEWKKYRVLVNRVDTSTAPKIDWPKKPEQPRTL"
     gene            complement(2236..3060)
                     /locus_tag="OPY25_002158"
     CDS             complement(2236..3060)
                     /locus_tag="OPY25_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macro domain-containing protein"
                     /protein_id="HCS0927768.1"
                     /translation="MIKLILSAPVPAMAVAFEHSFQNTENVEIIPGPFETITQFDCMV
                     SAANSFGLMDGGVDAAITAYFGPQLQERVQQNIIREYLGEQPVGSAFVIETGNSKHPW
                     LVHAPTMRVPLIIDGTDAVYNATRAALLAIFQHNKSAGEGRKIKSVVFPAMGAGCGKV
                     SPDSVARQMRLAWDGFINCATEINWQYASARQNAVFSTTAYCPSKTLCPNARTEYIGF
                     GDYRTYCKKSGNTCISPRHQVDDIYIGAHSHAVSPGTYPHSHHLNTEYLSGVKNDV"
     gene            complement(3057..4766)
                     /locus_tag="OPY25_002159"
     CDS             complement(3057..4766)
                     /locus_tag="OPY25_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000583382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCS0927769.1"
                     /translation="MIIGFGNNVVSSLAADITASQTTIQVMPGAGAMFANLLTSDYAN
                     SSNPLKTYAKITLTDAKETVFEVCHLTAVNNDMLTVIRGQEGTTAKGWSLNDVIANFA
                     TRGSENQFVQIEELQSGHYVAGVAGGTENNLTLELPATYFVNGGVDWTLRTPLVVIPA
                     LNNTGASTLQLTMGGRVLGKFPLYKGNKAELSANDIIKDAPVLCVLDNTKTYFSVLNP
                     LEIYLGSRYLQKNQNLSDVPDKAKGRSSLEVYSKTESDENYMAKSQCGADIPNKPLFV
                     QNIGALPANGTAVAANRLASRGALPALTGATRGSDSGLIMGEVYNNGYPTQYGNILRL
                     TGTGDGEILIGWSGVNGAPAPAYIRSHRDNAEAEWSEWAMLYTTLNPPPDSHPVGAAI
                     AWPSDATPAGYALMQGQSFDKSAYPLLAIAYPSGIIPDMRGWTIKGKPISGRAVLSQE
                     MDGNKSHSHTARAQDTDLGTKSTSSFDYGTKSTNTTGNHTHQFGGYINSYWGDSNHTS
                     FQPGGGAWTQAAGDHAHTVYIGGHEHTMYIGPHGHVVIVDADGNAETTVKNIAFNYIV
                     RLA"
     gene            complement(4763..5389)
                     /locus_tag="OPY25_002160"
     CDS             complement(4763..5389)
                     /locus_tag="OPY25_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927770.1"
                     /translation="MAALLESIIPAYPYTQYNDDPDIVAFFDAYNKLAQGYLDYFNNL
                     NLPCWTSPAITGELLDWIAAGIYGESRPLLQISEDAIARGAYNTIEYNNVAYAKLRNY
                     VPGSASYVPDDYFKRILTWNFYKGDGSHFCINWFKRRLARFIHGANGIDPPVQSTFDI
                     SVMPDKGIFFVSIPDYGDGVGHFLKDAIDQSLVKLPFIYTYSVTVVEQ"
     gene            complement(5373..6599)
                     /locus_tag="OPY25_002161"
     CDS             complement(5373..6599)
                     /locus_tag="OPY25_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCS0927771.1"
                     /translation="MSDLPISYDIAGPVPKTTDELRQLVIDTATALSPGITTNLPGSL
                     IEDLVSTSVGALVVCDQARVDLINSCSPYSANVHLLAQLGDMYGVQKGQGTNTSVYVV
                     FSGPPGFAIPKGFMVGDGTYTYTVQRDTMIPESGQTEPVYCLATTGGSWAVPAGTVNQ
                     IKTSVPNTYNLTCTNLTAGLPGAQEQTFSSYRAQVFQAGMYGVQGTPDCYRIELKNVY
                     GVQENLISYRQASLGAWVAIAGGGDPYEVAYAIYKAVPDISVLTNDVVNPSGAAVDKK
                     TIPIIVYPDTYHVPFVVPSSQNVTLLITWNTASTSYIDPTGIEKAVQQSIADYINGIA
                     TGEPINIFLIRDIFLNQVKGLVSSNLVSMIDIQVGINGKIVPPATDSSLVYGDTYAYF
                     STSSSQIQVKQYGSSS"
     gene            complement(6596..6928)
                     /locus_tag="OPY25_002162"
     CDS             complement(6596..6928)
                     /locus_tag="OPY25_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927772.1"
                     /translation="MRTYGRDKDGKWVTVTTDENGFNDSVYLTTLVQNLKLSPQESPF
                     FANHGIPANGSVIQQILPTFYVNRLQQQFSKYFSSLQIALADVDPPVYNISAITNSGS
                     KIVAQVYV"
     gene            complement(6925..7641)
                     /locus_tag="OPY25_002163"
     CDS             complement(6925..7641)
                     /locus_tag="OPY25_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927773.1"
                     /translation="MSINKKLNFGGNMNNFADQKIAAAMQMAGKILPAEVVSQSGKMV
                     TVTFLLRDIPYTLPQLTIPLFGPQYIRYPMQKGDKGIVIPADTYLGGASGLGGGTADL
                     TPPANLSALVFLPISNTEWENVDGQVLTLYGPEGVTIRDAKSNTTFLLTPESITIATP
                     EKFEVTVGSTVLTLTAGTWSLTGQSGTLTDSAASTSPKIMLEGWEKLVQWVNSHRHSN
                     GNDGQDTGGPTSQFNGSITE"
     gene            complement(7638..8681)
                     /locus_tag="OPY25_002164"
     CDS             complement(7638..8681)
                     /locus_tag="OPY25_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927774.1"
                     /translation="MRFYDIQIFNAPDAKGNPGTLYRQYSSMKNGVFNPGCLMVEFDL
                     LRFGESTPKGQSCITVWGISPQEMQQARQDMFGMTIKMWVGMSKGLPLAKPEQRGLVL
                     EGTIWQVLGNWQGTELRLDLIVTAGPVSDVNPLPLAPVNLTVPWNKGVKLSVALTQCF
                     QTLGGDYRFSVSISDRLVNNYDSNMFCGSLQELATRLNSLSKSIIKDSNYSGVEIAMV
                     NGREIRVFDNDFVNHQDKDSKKSASYRSKNPVQIEFTDLVGQPTWIQFGTVSIPCVMR
                     SDIQVGDYIRMPKKLRPMIQASSYSQFRDDSAFTGDFLVSSVRLVGNSRQPDANSWVT
                     VIEAHPTGGIAAT"
     gene            complement(8681..8956)
                     /locus_tag="OPY25_002165"
     CDS             complement(8681..8956)
                     /locus_tag="OPY25_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927775.1"
                     /translation="MSMAYYPFSGNEQKSMVFTPVLDGEVYNCQTKWNIAAQRWYLNI
                     TDNSGRRQLTIPVIGSPKNYDINLLVGAFSKTRMVWRVSDGQIEVFN"
     gene            complement(8953..9669)
                     /locus_tag="OPY25_002166"
     CDS             complement(8953..9669)
                     /locus_tag="OPY25_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000011137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927776.1"
                     /translation="MSFTRELYKLGFEISPVILCDGVAQSIPGGMLPIVALTQSASYV
                     SGLMGGAIELTDLDKYFCHWRAAPGGTMVDYDIGRYPFANQAVAANALLSQPLRIPML
                     MDAPVNENTGAMTKLVTLSSLQAVLQAHASLGGTFIVATPGIIYSNCILRTVRDVTGS
                     NDALPQRQWLWDFEQPLLSETGAEQAINSYLGKIDNGDKATESAWTSTISAIGNTSLG
                     SSVSGAVIGLIGKLSGAFNL"
     gene            complement(9669..11723)
                     /locus_tag="OPY25_002167"
     CDS             complement(9669..11723)
                     /locus_tag="OPY25_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927777.1"
                     /translation="MAAKSIVEIDVQDEKFQSFLEKFNEYQKALGELPEQWRGAVHGL
                     GEAAKETERVRDGTEGITKAFTDGVAALASVNDGLDRLNGNLEKATKTQTEFNKKSGG
                     ARNFLNKASKDAKSLAGHIKDATTSLLSWGTVLGLFSGLAGAGGLWGLNHLAGNASAQ
                     RFTAMGLGTTAGGLNSTAVDFQKALGNPVGTLGAIRDAQLDLSKRWQFRAMGVDNPDR
                     DPAELLPEMIKAARDIFVRNGSTQQGAEAYGLTNYFTLDDLNRFKKMSDEEIDAMAKQ
                     AQQDTRRLQLTDQQLRQWQDFNIQLDRSKVSIGNTFIRGLAPLAPELGKLSDAFSGAI
                     ETVLKSPELGKWIDGLSDGIRRFGNYLASPEFQKDVEAFISGVERLGRVIGKVIDWIS
                     GKSDITADDIKSRSSILSDEKRTDPVTSETYTPGGDDDPRVWSWLKGVKKFFASGDVK
                     PVDGKQADVHAKGRTIADRFNNPANLRYAAGYETANTRSGKFAVFPSLDEGVLAAAKQ
                     LQIYGTKGINNIHDIISKWAPSNENNTKAYIGHVVNATGRSEFEKLNLNDTRTLAKLI
                     TAMSVKEGAGSRLSEGKVIQIINNAGGHFQESQKKSLQDINPSDSVREQYLAQYGSEL
                     PGTSTSNPVVQPVQQGSGKTDQILQQILDNQKRGHAQGLVVYNNTGGNAVVSSTQLGG
                     FG"
     gene            complement(11847..12434)
                     /locus_tag="OPY25_002168"
     CDS             complement(11847..12434)
                     /locus_tag="OPY25_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927778.1"
                     /translation="MGVKIDRKLNFVSTITRDDGSLVYLHVVPFSYEVVEENCVLLGN
                     LFNNFFSLVGSVGAPRVAAMMLRKIIKAWQKAGDLQPGTPNIVDEIQRLTTVIWNDNG
                     TWKTSSLEAAFRQEIITDDEYREVEGEVVFFMVSSAIQKANLIAPTVGKALDMYSGQL
                     VSLSAMAYRDSLPTSKTVTDTPTPEALPEPSHIPS"
     gene            complement(12434..12871)
                     /locus_tag="OPY25_002169"
     CDS             complement(12434..12871)
                     /locus_tag="OPY25_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927779.1"
                     /translation="MPNPLVPQGFLNRVRGAVTVTDIPALNVTASFLGKDAISMRPDS
                     AATDIIPTLTGTVGSQVPYQQVTITMHLLRTQGLAASYQNRFASDTSLGEVVITPDAS
                     TFGNYTVLNAYLVNFNELTINGMDAGYVVTISGYLITNDKMWG"
     gene            complement(12875..14269)
                     /locus_tag="OPY25_002170"
     CDS             complement(12875..14269)
                     /locus_tag="OPY25_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927780.1"
                     /translation="MAIVNINVSVTSPPKPSQLLKSGALVSTGGTTLAAGSYQLLTSK
                     DDLKNIVAPAKAISSLAWAGNTVTVTLSENHGWSIDETIPVVISGAAPAAYNGAYTAS
                     VTGEKTFTYPLNSDPGTATVTGTVTSVAAGELQQMNTTYWAQGTSRAVYVLELGEMNV
                     KSAVAALGTFIDEDTSLGNTYQKFFSYLVPREWDAEPTFKTLANNYTSPGALVKFFVT
                     TTIATYQEWVSGKYPNVFAGVEAPSIGATEFSMAAPFQSSLANDPGSSNMVPPMAYRF
                     MYGVTEYPPAGNGTLLKTLQDNHINYIGTAAEGGLSNKMLVAGHMLDGMPFNYWYSVA
                     WCAINLELDLANEVINGSNTTVNPLYYDQQGIGRLQRRALKTLRSGISYGLILGQVID
                     TQLTQESFNAEYEKGSYAGNAVINAVPFADYTSLNQSDYADGKYNGLSAVVTPRRGFE
                     SITFNLNVTNFVGA"
     gene            complement(14275..15213)
                     /locus_tag="OPY25_002171"
     CDS             complement(14275..15213)
                     /locus_tag="OPY25_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927781.1"
                     /translation="MPSLSELSQAKTELNASLVQGLDDISRSASVTFTKYVRKVLPLD
                     GFVFWVKASVLADDPDTEPDTKEVKGYLHLTTESIQDEEQLYDKNVVTFTAQADIDPF
                     NDIGSEVLYIGEFYGIQFAFSRRSGLNEPANIYHYTGHAIYPHMMSQIINSADDIDLA
                     DVVVSNSLPIWLSLSHFMPMYPAMLSVQNLAPPYATVKCGEPSPVAGAFCLDEKQNQY
                     QLVSEDVTLTVTGLRNAAVEDFLRYVQDYTLSDKAEMGVMNIPVIQDERVTQNELNII
                     AMRKKVKFKVNYYQQRMRNVARRLITSAIPSIYVEK"
     gene            complement(15197..15607)
                     /locus_tag="OPY25_002172"
     CDS             complement(15197..15607)
                     /locus_tag="OPY25_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927782.1"
                     /translation="MDIPYENENTTTGDVAEILEGKYRIMQTFFDRHGEEIAQMMSND
                     LAAGLENMLAGAPLPADPFAESMSQAHHLFVAFLDNEEMNGTEGVPTARALEGISKRF
                     KNRKGEPRPSFIDTGMFQASMRAWVSGVLNAFPQ"
     gene            complement(15625..16050)
                     /locus_tag="OPY25_002173"
     CDS             complement(15625..16050)
                     /locus_tag="OPY25_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927783.1"
                     /translation="MPELAGFILFIRNTMGVNADALADDDPAVSLSWSMSLDWVNRQI
                     ACISPVLYSQAVYNLAASFLLNFGPEVAFGPVREKLGINNFTAGVISTSSDESTSQTR
                     VVSDALKNLSLADLQQLKDPYGRWYLAIAQQYGDLWGLT"
     gene            complement(16063..16548)
                     /locus_tag="OPY25_002174"
     CDS             complement(16063..16548)
                     /locus_tag="OPY25_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927784.1"
                     /translation="MKLYIANTTKQRHDFAWRKPETGRLVYHPINAGSQAVVIDGTRA
                     EIDLIIQQHADYGLIDATKIDQNRIYIGLCYSIDKPVSSKVIEKAMRDNDGHLNRAAH
                     DRRQASVLATNNALTEQENGYLGELEVSAEQRLNATDDRDETAFVDETLAVNTGTKKK
                     K"
     gene            complement(16613..17644)
                     /locus_tag="OPY25_002175"
     CDS             complement(16613..17644)
                     /locus_tag="OPY25_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2184 domain-containing protein"
                     /protein_id="HCS0927785.1"
                     /translation="MPAITPAYQIVNPSYIMPEMILSYQQASGAFSVMASGNPLVRLA
                     DGDQYVYMKRLDIRTQVTSSQSGNANQLPSVALEARMVSTPTYMFRARAIYDHHDMAA
                     AGNWGIALPEAQRLGTRQAIFQQMRNALLYGMNPAGGEGVLNTNGATTISLPADSRGN
                     TTVLTYDHGEMAVFLLAQIQAIRTRTMQMGRASRMVILGPQRTLGTMEMQQIVQLTSY
                     QRPGGGTSTVKGTVNGVGDDADCEIEWGYDDTLIGAGANGTDAIVIAMPEVERPEVNA
                     KINTNEFARLSPSLEATSLMLCDMAAPREIPTPIAGGAIDVLSELRSTSGWVLRPEAL
                     TIISMKYSD"
     gene            complement(17662..18534)
                     /locus_tag="OPY25_002176"
     CDS             complement(17662..18534)
                     /locus_tag="OPY25_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927786.1"
                     /translation="MASALSVNPMQTTNARGTFYAKSDGLIQGVALDDPAARYALASG
                     TLASDEIKPLWGGLPVNELVPGASSAPRGSIIKRAASLSQLVGFSVFNQAHNGLTTPQ
                     SPVPLLLSNMSVSFYRLGSGMRVPVKASDAVISLASAGISVNQPLVWNFAEDCLDVFS
                     TAAADVATTAITWTAPTANLAGFATATAASAHGLKVGVYVDITGAAPAAYNGIVQVLS
                     APTATTFTFTPVSVPAGNATTQGTVGAAKVQDVALPVKIIEMQMGNSKTVSYDSATGF
                     ATWNDSGNAAVILL"
     gene            complement(18555..20129)
                     /locus_tag="OPY25_002177"
     CDS             complement(18555..20129)
                     /locus_tag="OPY25_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCS0927787.1"
                     /translation="MKTYAAGILFKSGGKIFLVKRGDDGSWAVPGGKLEEGETPESAA
                     RREVLEECGFDYSAPLTPHTLIDGYVTYLADDAEQFDAVLNDENQACGWFSPNELPDP
                     LHPGMVAMLDAEPLNEMDVAGLIADGQLTSPQFFRNMYLWALRITGTGVTWRSKFRQY
                     AYRSPENYLTDEFLARCSGLPVIWWHPEKNTLNSEEFASRTIGAITFAWIKGDEVWGM
                     ARIYDTDAAANLSTRQLSTSPTVTGGDDVLIDVDGEPLLLEGTPVLLDHLAICEQGVW
                     DKLGEPMGVKSDTLLNEVQKMDEEKVLALINQALDAREARAKADAEEKAKADAEAAEK
                     AKADEDAARLKEEEEKAKADADAKAKADAEAEEKAKADAELEKIRADMEEMKSRVPQE
                     LSDEERNEIADTQCKADSVFASFGERAPQPMAGERAMPYRRRIMTRLQKYSPDYKEVD
                     LHAIADSQLLSIAEKKIYADAQASAASSLEPGAGLREVIRTDATGRRISTFIGDPSAT
                     WAPFQAVSRKVAGIKQ"
     gene            complement(20130..21005)
                     /locus_tag="OPY25_002178"
     CDS             complement(20130..21005)
                     /locus_tag="OPY25_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927788.1"
                     /translation="MASFVKELRDAIKHFLEYGYSSEESLIMWTERLRNATENKVDGN
                     DLYRYVSRRLTAAYDLEIGREKALKRHLGVSRFTLNYLEPKLRAELDRRIMASADLIK
                     LNRTQAIDKTIQRFSGWATSIPPISEMSVGLSASSRSGVIATSQHIAKSARQIDFEQR
                     RVMVDQTHKLIANIDNIIATEGGAIAAVWHSHWRQPNYDFREPHKERDLLVYAIRGNW
                     AIKKGFMKVGPAGYLDEITQPGEEVFCRCYLTFIYNVRSLPDEMKTEKWRKFIEGNKS
                     VGRRSANFETIKNGG"
     gene            complement(20977..22416)
                     /locus_tag="OPY25_002179"
     CDS             complement(20977..22416)
                     /locus_tag="OPY25_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001150139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1073 domain-containing protein"
                     /protein_id="HCS0927789.1"
                     /translation="MQDDDDICMGSNAGVLSKILEGGSIEPGAQAGYELCKLIYLFHP
                     LGGKMVDRPIKLAMSEPRTVHVTRGPERRLREAFEREWKAIKADRIIANTARQSRIYG
                     VGAVVMLIDGEPTNEAAEFDTLYKKSITFNVLDPMNTAGSVVLNQDPNSADFQKVGSV
                     TAAGQPYHHSRCCVMMNEDPIYLAYTPSSFGFAGRSVYQRALYPLKSFIQSMRADDMV
                     TIKAGLLVAFIKQASSIVNNMMQKMSGIKRWMLKRGGNGDVLQVGENDKIESLDMQNL
                     EKPLDTARNHILANIATAADMPAILLNSETFTRGFGEGTEDAKAVAQYIDDVRKDLEP
                     LYDFFVRIVQYRAWSREFFEALKNDVPEYEKITWEAAFNSWVNNFDYVWPSALKEPES
                     EKVKVDETRFKAITEMLNVLLPQLTKDPQNRATLIKWACENANMNENLFADRLELDYE
                     LLEQCPPDPPPTGNDNEDNYDGLIRERAA"
     gene            complement(22416..23687)
                     /locus_tag="OPY25_002180"
     CDS             complement(22416..23687)
                     /locus_tag="OPY25_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016152532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927790.1"
                     /translation="MATEHVIEFLPFHAGQKKIYRSPAKRKVIRAGRRYGKTTMLEQA
                     GGNWAARQMRVGWFAPSYKILLPSFKAIRDLLKPITISSSKTDAIIETIGGGQVEFWT
                     LDNPDAGRSRKYHKVIIDEGSLVKKGMRDIWEQAIEPTLLDFDGDAVMAGTPKGVDDE
                     NFFYQACNDKSMGWEEHHAPTAANPTINPAALARIIDGRPPLVVQQEYNAEFVDWRGQ
                     NFFKLDWILEDGAPVDYPFSCDTVYGVVDCAQKGKLQNDGSACIWFALDNLPSPHLVI
                     LDWDIIQIDGYFLKDIVPQWEGKAKQLSEICRARMGTTGLFIEDKATGITLLQQGANE
                     GWNVHPIDSDLTSLPKESRAINISGYVASGKVRISKYAFDKIVEYKQSKKNHLLTQVL
                     KFIIGEEDQDDDLFDCFNYGVALGLGNGEGF"
     gene            complement(23677..24648)
                     /locus_tag="OPY25_002181"
     CDS             complement(23677..24648)
                     /locus_tag="OPY25_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HCS0927791.1"
                     /translation="MAKPDWGALQHQFLSEHAKSGISPKDWCEAQGLNYTSARRYIKK
                     PTAQNAQQSAQKKMRTAQARKSAEKLLDSELTPQQKRFVAEYLIDQNATAAAERAGYS
                     DASYGRQLLTLPHVAQAIAQQQRDSLVRTLVSADEVLEKMWQLATFDANEISQYRRGC
                     CRYCWGFGHHYQWRDVIEFEEREAEAKAKKGKEPDDAGGYGYNHNRDPNPDCPRCNGD
                     GVGRPYFADTTKLSSIARLAYSGTKLVKGGIEISTISREKMFEAIMRRLGLTESELAQ
                     RLLDLEIRKRTAEAERLEQEVELKRKGKGKDDEPTVVIKLVNSPDGD"
     gene            complement(24747..25067)
                     /locus_tag="OPY25_002182"
     CDS             complement(24747..25067)
                     /locus_tag="OPY25_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="negative regulator GrlR"
                     /protein_id="HCS0927792.1"
                     /translation="MKDGIYFVVFRSNQRDFGNGTVVVKNDAVNGGDFGFTYQGKIEG
                     NQLILRVSQHDLSVTSVFPGVKNFELSLSLQERGRDYQLNGSVVGMPQMQISIGAKYI
                     GDLI"
     gene            complement(25208..25738)
                     /locus_tag="OPY25_002183"
     CDS             complement(25208..25738)
                     /locus_tag="OPY25_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 family protein"
                     /protein_id="HCS0927793.1"
                     /translation="MVLALIRKYWKPLAEILLVAFLLCATAYWCYSRGYQEADSSWKL
                     QWAQRDLTDATITLQREVTERAEEQRRQLAVDKEREKADEELAKVQADADAAKRARGG
                     LQQQLAEIQRQLATSETGRISAIAAASQAKAETGILLAQLLGEADDLAGKFAKEADER
                     YVAGSACERTYDKVTK"
     gene            complement(25741..26157)
                     /locus_tag="OPY25_002184"
     CDS             complement(25741..26157)
                     /locus_tag="OPY25_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004169539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="structural protein"
                     /protein_id="HCS0927794.1"
                     /translation="MTTKTPRGIRNNNPGNIRWGDDWKGLVPKDQRTDKSFCQFTTPE
                     YGIRAMIIILRNYQRKYGLDTVSGIIKRWAPPNENITQAYINSVAQATGVTPDQRIDT
                     NDSRFMIKLLQAIIKHENGNQPYSSDTFDRAVEQAG"
     gene            complement(26160..26507)
                     /locus_tag="OPY25_002185"
     CDS             complement(26160..26507)
                     /locus_tag="OPY25_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin, lambda family"
                     /protein_id="HCS0927795.1"
                     /translation="MPHNPNTWPDWLELFQSWWRGDTPLGAVLMSLCMAGLRIAYFGG
                     GGGWKKKTLEILLCGALTLTFSSALEYFGWPKSLSVAIGGGVGLIGVDAIRGFAMRLI
                     GNRLGVGSDNNKV"
     gene            complement(26947..27525)
                     /locus_tag="OPY25_002186"
     CDS             complement(26947..27525)
                     /locus_tag="OPY25_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1133 family protein"
                     /protein_id="HCS0927796.1"
                     /translation="MINPSTTGKGGEMLRLNTLESVWIQGKLRMWGRWSYIGSGSGGH
                     MFNNLLASKKVSKTAIQQVLKHLKSSGLDHGELMSYFLDMLSGKEKSNLAFCTDEEGL
                     LMDAVIGEILVRTGHQRLFKLVVDRYKDRMSKKAMARELNTRHPEWCLRTCESRIDVW
                     LQMAEAMLYLPMCDVFDKKADRFRLQICAGIA"
     gene            complement(27522..27815)
                     /locus_tag="OPY25_002187"
     CDS             complement(27522..27815)
                     /locus_tag="OPY25_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HCS0927797.1"
                     /translation="MKKIDLTKQARGRMCTVRIPGICNFDPETSVLAHYRMSDTCGMG
                     IKPHDMQGAIACNCCHDVIDGRVKTDIEQDTLRLYHAEGVFRTQQIWREEAFI"
     gene            complement(27812..28408)
                     /locus_tag="OPY25_002188"
     CDS             complement(27812..28408)
                     /locus_tag="OPY25_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1367 family protein"
                     /protein_id="HCS0927798.1"
                     /translation="MAQYSFVKSAGGVLIPATPDAREFIEKKFRLGAVLYADFKQARN
                     AAFHRKFFALLNLGFDYWQPSGGAISPADKKLVRGYVQLVAHYAGHEETLQELADQYL
                     REEAEKRAGNISAVKSFEAFRAWVTIEAGFYTQYEMPDGTTRNEPKSISFAKMDDLEF
                     SQLYKSVLDVLWNYILFRTFPTQQAAENAASQLFSYAA"
     gene            complement(28476..28667)
                     /locus_tag="OPY25_002189"
     CDS             complement(28476..28667)
                     /locus_tag="OPY25_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000474096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927799.1"
                     /translation="MFKKMEIGKQLPDNGRVLITCKNGQVTALRKIYDDEHVASLKSL
                     LELAEQAGCVVVQRGKTKI"
     gene            29052..>29327
                     /locus_tag="OPY25_002190"
     CDS             29052..>29327
                     /locus_tag="OPY25_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012773202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCS0927800.1"
                     /translation="MIKWYRFKNFHSFKEEQFVDLTLKANSSESPLDQQWGDDRIAKV
                     LAVMGANGSGKSNMIKPLAFLSWFCSDSFKSMDNSDSLPIYPHICNKS"
BASE COUNT         7078 a         7748 c         6815 g         7686 t
ORIGIN      
        1 gggttacctt tcggtaaccc cttgtttaat ctggcggaag cgcagagatt cgaactctgg
       61 aaccctttcg ggtcgccggt tttcaagacc ggaaaaatat taatataaat caagcaatta
      121 tgtttattct aaagaatact atgaaaaatc accatccatg aaaaacaaca tgttagctta
      181 gctttgatca cgaaattccc cgaatttatg cgctcacctt gactaaaatc tgaaattcac
      241 agatattata ctgtataaaa aaacagtacg gaaatatcac atgagaacca ctgaatctaa
      301 cgtaagcagc ttacccgaac tcaccagttt cgaagtaggc tattcccttc gaactaatga
      361 agtttacctg tccgcttcat tcacagataa catggcctgt ataccaaact ggccaattaa
      421 agagtttcct gaccagttta tgtgtatctc tcatactcgg gcggttgcac tcatagaaga
      481 gcttcaaaag gctatcgact acatgaacgc ggggatagaa cgtcgctcag aaaatttaat
      541 ccagtaaata ggaaggttta ccctattcca ttacatcttt tgcaacagca tagattctag
      601 acaggtacgc atcatcactc tgatccgagt gcgcttgcag catcaggttt atgctgtttt
      661 tggtaactgg ctgattagtt tcttttagca tgactactgc gcgtccaata accctgcata
      721 catcgtcaaa aacagcttgt ttttcctcat ccataactgt ttctcgctct gttatcgctg
      781 aaccaacatc attgtaatat aggccatagt gcaccattta tgtctatata tttctatggt
      841 tataaacata ttgatatgta ctttatttaa cctttttaca atcaaataca tcaatactac
      901 ccgcaaattc gagtgccgaa gtgtgtgtta ccaccgcccc gttaaattgg cttacaggca
      961 aagtattaaa tatttgaatt tcgtaagcat gaccatcata actagccgat acggttatgg
     1021 agccatcagc cgcccgtcca tatcgctcac ctgagtcaga atcaacaact tctaattttg
     1081 gtgagataat ctgcttatcg tcaggaaaaa ggaaaccaac ggaatcaacg ttgtccttta
     1141 cacgtactct catgcgacta gtatcaactg gcccaccaga ttgatttaac gtcattcgac
     1201 aataaaaaag gtctcctttt tttactgatg tttgtttatt tttattggct attttttgcc
     1261 gtttcttctc tattttttcg ttctcagaat aatacatact aacagtgcaa tacctatccg
     1321 aagattcaaa gcatttatca accaatcggt ggagaaattc acttgtctcc ccaccattat
     1381 caactagttt agttcgtaac acagtaacgc ttagaggagg ctgatgtacc aatgactgag
     1441 gaactaaaaa acttggcacg tactgcgggc catactccaa taggtaatcc cgcttttgct
     1501 caattgtttt tgctttacct ttatcccaag cactacaacc gatcataaaa aatgacaaca
     1561 aaactactat accaatttta ttcatttttc atccctaaac atatgtaccg ataagcgcag
     1621 tgtacaccat caccactgcg tctcaaatca acctataagg tacgcggttg ttcaggtttc
     1681 ttaggccagt cgatttttgg cgcggtcgat gtatccaccc ggtttaccag caccctgtat
     1741 tttttccact cggcgagctg gcttttctct tcatctgttg cgagtccaag atcaaccgca
     1801 tcctgaagcg gcgcgatttt ccccgatgcc atttgcaaaa gacggctttt ggtcccttca
     1861 gcttcacgaa gtctgaccgc tgtttccgca gcttcatcct tcacccacgc cttaccatcc
     1921 catttctggt attcacctcc tggtgaaact gatgtgacat tttcgggcaa cgggccgggt
     1981 tcggagatat aaacctgatt gccggttgtt gtgtcgtaaa ccatctcgcc gcggtgatcc
     2041 tcatgcaaac tccatgtctg ggtttcagcg tcaaatacag caatatgact ggcgggaata
     2101 tcaggagggg cgatattagt acagtttgcc ggtagtcctg tgtgcggcgg gatatatgca
     2161 tcacctgcgc caataaattc gtttgtatct gaacgaagat taaaaatttt aattgtctgt
     2221 ggggtgtcgc tcattttaaa cgtcattttt tactccggat aaatattctg tattcaggtg
     2281 atggctgtgg ggataagtac cgggggaaac agcatggcta tgtgcaccaa tataaatatc
     2341 atcaacctga tgacggggac taatgcaggt gttacctgat tttttgcaat acgttctgta
     2401 atcaccaaaa ccgatatatt ccgttctggc gttcgggcaa agcgtctttg acggacagta
     2461 tgccgttgtg ctgaatacag cattctggcg ggcgctggca tattgccagt taatttccgt
     2521 ggcgcagtta ataaaaccat cccacgccag cctcatttgc cgggcgacac tatccggtga
     2581 taccttacca cacccggccc ccatcgcagg gaacacaacc gatttgattt tccggccttc
     2641 cccggcgctt ttattgtgct gaaaaattgc cagtaacgct gcccgtgttg cgttataaac
     2701 cgcatcggtg ccgtcgatta tcagcggaac gcgcatcgtc ggagcgtgaa ccaaccacgg
     2761 atgtttactg ttacccgttt caataacaaa ggcgctgccg acaggctgtt ctcccagata
     2821 ttcacggatg atattttgct gtacacgttc ctgtaactgc ggcccaaaat atgctgttat
     2881 cgcagcatcc acgccgccat ccatcaaacc gaaagagttc gccgcactga ccatgcagtc
     2941 aaactgagtg atggtttcaa acggtcctgg gataatttcc acattttcgg tattctgaaa
     3001 agaatgttca aaagccacgg ccattgctgg cacgggtgct gaaagaatta atttaatcac
     3061 gccagcctca caatatagtt aaatgcaatg tttttaaccg tggtttccgc attaccgtct
     3121 gcgtccacaa taacgacgtg tccgtgtgga ccgatataca tggtgtgctc gtgtcctccg
     3181 atataaactg tatgcgcatg gtcgccagcg gcctgtgtcc atgcaccacc tccaggctga
     3241 aatgaggtgt gattggaatc tccccagtat gagttgatat aaccgccgaa ctggtgagta
     3301 tggttgcccg tggtattggt cgatttcgtg ccgtaatcaa aggatgaggt ggattttgtc
     3361 cctaagtcag tatcctgcgc ccgcgcggtg tgcgagtgcg atttgttgcc gtccatttct
     3421 tgcgacagta cagcacgtcc actgatgggc ttacccttta ttgtccagcc tcgcatgtca
     3481 gggataatgc cggacggata cgctatagcc agtaacgggt aagcagattt atcgaaggac
     3541 tgcccctgca tcagagcgta acctgccgga gtagcatcag acggccatgc aatcgccgcc
     3601 cctactggat gcgaatccgg aggtgggttt agtgtggtgt agagcattgc ccattcggac
     3661 cactcagcct cggcgttatc tctgtggctg cgaatatatg caggcgcagg agcaccatta
     3721 accccgctcc atccgatcaa tatctccccg tcaccggttc cggtcagacg taaaatattc
     3781 ccgtattgtg ttggatagcc attgttgtaa acctcgccca ttatcaggcc gctatcgctg
     3841 cctcttgtcg caccagtcag tgccggaagc gcaccgcgtg atgccagtct gttcgctgca
     3901 acagccgtac cgttggcagg aagcgctccg atattttgta caaacagcgg cttattcggg
     3961 atatccgcac cacactggct tttagccatg tagttttcat cactttcggt tttgctgtag
     4021 acctcaagac tggaccgacc tttggcctta tccggtacgt cggacaggtt ctggttcttc
     4081 tgcaaatacc gtgatcccaa ataaatctcc aggggattaa gcacagaaaa ataggttttt
     4141 gtattatcca gaacgcataa gacaggagca tctttaataa tatcattggc cgataactct
     4201 gctttattcc ccttgtatag tgggaatttg ccaagcacac gcccccccat cgtcagttgc
     4261 agagtgctgg ctccagtatt gtttagcgcc ggaataacca caagtggagt gcgcaatgtc
     4321 cagtcaactc caccattgac gaaataagtt gctggtaact ccagcgtcag attattttct
     4381 gtacctccgg ccacaccagc gacatagtgc ccactctgga gctcttcaat ttgtacaaac
     4441 tgattttcag atcctcgcgt cgcaaaattc gctataacgt cattcagtga ccatcccttc
     4501 gctgttgtac cttcctgacc gcgaataacc gtcagcatgt cattattaac tgctgtcaga
     4561 tggcatacct caaaaactgt ttcttttgcg tctgtcagtg taattttggc gtaagtttta
     4621 agagggtttg agctgttcgc ataatcgctg gtaagcaaat tagcaaacat cgctcccgca
     4681 ccaggcatca cctgaatggt cgtctggctg gcggtaatat cagccgccag tgaggagacg
     4741 acattatttc cgaatccaat aatcattgct caaccaccgt taccgaatag gtataaataa
     4801 aagggagttt caccagcgac tggtcaattg catctttaag aaagtgtccg acaccatcgc
     4861 catagtcagg aatggagaca aaaaaaatgc ccttatcggg cattacacta atatcaaaag
     4921 tggactgtac aggtgggtct attccgttag ctccatgtat aaagcgtgca agccgtcgtt
     4981 tgaaccagtt gatacagaag tgcgaaccat cgcctttata aaaattccat gtcagtatcc
     5041 gtttaaaata gtcgtccgga acatatgacg ctgagccggg aacataattt ctcagttttg
     5101 catacgcgac attattgtac tcaatagtgt tatacgcccc acgagcaatg gcatcctcgg
     5161 agatttgaag caaggggcgt gattccccat aaatacccgc cgcaatccag tccagcaact
     5221 caccggtaat cgccggggag gtccagcaag gtaaattcag gttgttaaag taatcaagat
     5281 acccctgtgc cagtttgtta taagcatcaa aaaaggcaac tatatccgga tcgtcattat
     5341 attgcgtata ggggtaggcc ggaataatgc tttcaagaag agctgccata ttgcttaacc
     5401 tgaatttgtg aagatgaagt ggaaaaatag gcgtaagtat caccataaac caggctggag
     5461 tcggttgcag gtgggacaat ttttccgttt attccaacct gaatatcaat cattgataca
     5521 aggtttgaag atacaagccc cttaacctga ttaagaaaaa tatcccgaat caggaaaatg
     5581 tttattggtt cacccgttgc aattccgtta atgtaatcag caatgctttg ctgcactgct
     5641 ttttcaatcc cggttggatc gatatagctg gttgaggctg tattccaggt gattaaaagc
     5701 gtaacgtttt gtgatgatgg cactacaaac ggcacgtgat acgtatccgg atacacaatg
     5761 atcggtatcg tttttttatc caccgcagcg cctgatggat tcactacatc attcgtcagt
     5821 acggagatat ctggcacggc tttatagata gcgtaagcca cttcataagg atcgccgcca
     5881 ccagcaatcg ctacccatgc ccccagcgat gcctgtcgat atgagatcag attctcctgt
     5941 acaccataaa catttttcag ttcaatccgg taacagtcag gcgttccctg tacaccgtac
     6001 atacccgcct ggaatacctg ggcacggtat gaagaaaaag tctgttcctg cgcgccgggt
     6061 aatccagcgg taaggttggt gcaggtcagg ttgtatgtat tcggtactga ggtttttatc
     6121 tgatttacag ttcccgcagg tactgcccag gagcccccgg ttgttgccag gcaatagaca
     6181 ggctccgttt gtccactttc cgggatcatc gtgtcacgct gaacggtgta ggtgtaggtt
     6241 ccatccccga ccataaaacc tttcggtata gcaaacccgg gcgggccact gaacaccaca
     6301 taaaccgatg tattggtacc ctgccctttc tgaacgccgt acatatcacc cagttgcgcc
     6361 agcaggtgta catttgccga atacgggctg catgagttaa tcaggtcaac ccgcgcctga
     6421 tcacatacca caagcgcacc gacgctcgta ctgaccaaat cttcaatcag cgatcctggt
     6481 agatttgtgg ttatccccgg ggacagcgct gttgcagtat caataaccag ttgccggagt
     6541 tcatccgtcg ttttaggaac agggccggca atatcataac taatgggtaa atcactcata
     6601 catacacctg agccactatt ttagagcctg agttagtaat cgccgaaatg ttgtaaacag
     6661 ggggatcaac atccgccagc gcaatctgta gagaggaaaa atatttgctg aactgctgct
     6721 ggagccggtt aacataaaaa gtcggcagta tctgctgaat aactgagccg ttagccggta
     6781 taccgtgatt agcaaaaaac ggggactcct gcggggacag cttcagattc tgcaccagcg
     6841 ttgtgagata cacagaatcg ttaaacccgt tttcgtcagt cgtgaccgtt acccacttcc
     6901 cgtctttatc tcgtccgtat gtcctcattc ggtaatactc ccgttgaatt gtgacgttgg
     6961 ccctccggta tcctgtccgt cattaccatt gctgtgcctg tggctgttaa cccactgaac
     7021 cagcttttcc cagccctcca gcatgatttt cgggctggtg ctggccgcac tgtcagtcag
     7081 tgttccactc tgccctgtca gcgaccaggt accagcggtg agcgtcagaa ctgtactgcc
     7141 caccgtcact tcgaattttt caggtgtggc aatcgtgata ctttccggtg tgagcagaaa
     7201 cgtagtgttg cttttcgcat cacgaatggt taccccctcc ggcccgtaca gcgtcagtac
     7261 ctgaccatcg acgttctccc actccgtgtt actgatgggt aaaaacacca gcgcactgag
     7321 atttgcgggg ggcgtcagat cagccgttcc ccctccgagg ccgctggcgc cacccaggta
     7381 ggtatccgcc gggatgacta tccccttatc tcctttttgc atcgggtatc tgatgtactg
     7441 ggggccgaat agcggaatgg tcaactgagg taacgtgtag ggaatgtccc gcagcaaaaa
     7501 ggtaacagtg accattttcc cggactgact gacgacctct gcgggtaaaa tctttccggc
     7561 catctgcata gcggcggcta ttttctggtc agcgaaatta ttcatattgc cgccaaaatt
     7621 gagtttttta tttatactca tgttgcagca atcccccctg ttggatgcgc ctcgataaca
     7681 gttacccaac tgtttgcgtc cggttgcctg ctgttaccca ccagacggac cgaagacacc
     7741 agaaaatccc ccgtaaaagc cgagtcatca cgaaactgtg agtatgacga tgcctggatc
     7801 atcggcctta atttcttcgg catccggata taatcgccca cctgaatatc gctgcgcata
     7861 acgcagggaa tggataccgt accaaactgg atccatgtcg gctgaccaac aagatcggta
     7921 aattcaattt gcacgggatt tttacttctg taagaggcgc tttttttgga atctttatcc
     7981 tggtggttaa caaaatcgtt atcgaatacg cggatctccc tgccgttcac catcgctatt
     8041 tcaacaccag aataattact gtccttaatg atgcttttac tcagcgagtt aagtctggtc
     8101 gcaagctcct ggagactgcc gcaaaacata ttgctgtcat aattattcac caggcgatcg
     8161 ctgatactga ctgagaacct atagtcacct cccagcgtct gaaagcattg cgtcagcgcg
     8221 acagaaagct taaccccttt gttccacggc accgttaaat ttacgggtgc cagcggtagt
     8281 gggttaacgt cagacacagg gccggcggtc acaataagat ccagccgtaa ctcggtcccc
     8341 tgccagtttc ccagcacctg ccagatggtc ccttccagca ccagtccacg ctgttccggt
     8401 ttcgccagcg gcaacccttt tgacattccc acccacattt ttatggtcat gccaaacata
     8461 tcctgtctgg cctgttgcat ttcctgcgga ctgatgcccc agacagtgat gcagctctgc
     8521 cctttgggag tggattcacc aaaacggaga aggtcgaatt caaccatcag gcaccccggg
     8581 ttaaataccc cgtttttcat gctactgtac tgtctgtaca gcgtaccggg gttgccctta
     8641 gcatccggag cattaaaaat ctgaatgtcg tagaaacgca tcagttaaat acctcaatct
     8701 gaccgtcaga aacacgccat accattctgg ttttgctgaa tgcccccacc agtaaattaa
     8761 tatcgtaatt ctttggggaa ccaataaccg gaattgtcag ttgccgacgg cctgagttat
     8821 ccgtgatatt gaggtaccag cgctgggcgg caatattcca tttcgtctgg cagttataaa
     8881 cttcaccatc gagaacggga gtaaagacca tgcttttctg ttcgttaccg gagaagggat
     8941 aatacgccat gctcataaat taaatgcccc gctcagtttt ccgattaagc caataaccgc
     9001 acccgataca ctactgccga gtgaggtatt accaatcgcc gagatggtac tggtccaggc
     9061 gctttctgtt gccttgtccc cgttatcaat cttgcccaga taactgttta tcgcctgttc
     9121 agccccggtt tcagaaagca gtggttgctc aaaatcccat aaccattgcc gctgcggtaa
     9181 ggcatcattc gatccggtaa catcacgcac cgttctcagt atgcagttgc tgtaaataat
     9241 acctggcgtt gccacaataa acgttccgcc aagactggcg tgtgcctgca atacggcctg
     9301 caacgaactc agcgtgacca gctttgtcat agcgccagtg ttttcattta ccggcgcatc
     9361 catcagcatt ggaatgcgca gcggctgcga gagaagcgcg ttggctgcca ccgcctgatt
     9421 tgcaaacgga taacgaccaa tgtcgtaatc aaccattgtc ccaccgggcg ccgctcgcca
     9481 gtggcagaaa tacttatcca gatccgtcag ttcaatagcg ccccccatca gacctgaaac
     9541 gtagctggcg ctctgggtca gggcgactat cggcaacatg ccgccgggta tactctgcgc
     9601 cacaccatcg cagagaataa ccggggagat ttcaaaaccg agcttgtaga gctcgcgggt
     9661 aaatgacatt aaccgaaccc tccaagttgc gtactggata caactgcatt accgccggta
     9721 ttgttataaa caacaagtcc ctgagcatga ccacgcttct ggttatccag aatttgttgc
     9781 agtatctggt cagttttccc cgaaccctgc tgcactggct gtacgacagg gttacttgtg
     9841 ctggtaccgg gcaattcaga accatactgg gcaagatatt gttcccgcac gctgtcggat
     9901 ggatttatat cctgcaaaga ttttttctgc gattcctgaa aatgacctcc ggcattattg
     9961 ataatctgta taaccttccc ttcacttaac cgggagccag caccttcttt tactgacatg
    10021 gcagtaatta atttcgcgag cgtccgggta tcatttaaat tcagcttttc gaattcgctg
    10081 cggccagtcg cattcacaac atgcccgata tatgctttcg tattgttctc gttagatgga
    10141 gcccatttac tgataatatc gtggatattg ttgatgccct ttgtgccgta tatttgcagt
    10201 tgttttgcag cagcgagaac gccttcatcc aggctgggga acacagcaaa tttcccgctt
    10261 ctggtattgg cggtttcata acctgcggca taacgtaaat tcgcaggatt attgaacctg
    10321 tcagcaatgg ttcgcccctt ggcatgaaca tcagcctgtt tcccgtcgac cggcttaaca
    10381 tctcctgatg caaagaattt ttttacccct ttcagccacg accacactcg cggatcatca
    10441 tccccacccg gggtgtaagt ctcactggta acgggatcgg tgcgcttctc gtcgctgagt
    10501 atcgatgacc gggatttaat gtcatccgcc gtgatgtcgg atttaccact tatccagtca
    10561 atgactttgc cgataacccg accaagccgc tccacaccgg atatgaaagc ttcaacatct
    10621 ttctggaatt cgggggaagc cagatagtta ccaaaccggc gtataccatc tgaaaggcca
    10681 tcaatccatt ttcccagttc cggcgattta aggaccgttt caatcgcgcc ggaaaaggca
    10741 tccgaaagtt ttcccagctc cggcgccagc ggtgccagtc cccggataaa cgtattcccg
    10801 atactgacct tactgcggtc gagctgaatg ttgaaatcct gccactggcg aagctgctgg
    10861 tccgtcaact gaaggcggcg ggtgtcctgc tgtgcctgtt tcgccatcgc atcgatttct
    10921 tcatcgctca tttttttgaa gcggttcaga tcgtcaaggg tgaaatagtt cgtcagcccg
    10981 taggcttccg ccccctgctg cgtactgccg ttacgcacaa aaatatcacg cgccgctttt
    11041 atcatttcag gtaaaagctc agcaggatcc ctgtccgggt tatcgactcc cattgcccgg
    11101 aactgccagc gtttactcaa atcaagctgc gcatcacgta tggcgcccag agttccgaca
    11161 ggattaccca gcgctttctg aaaatcgaca gcagtcgaat taagtccacc tgccgtcgtc
    11221 cccagcccca tagcagtaaa ccgttgtgcg gaggcattgc cggccaggtg gttaagcccc
    11281 cacagaccgc ccgcaccagc cagcccggaa aaaagcccca gaacggttcc ccatgaaagc
    11341 aggctggttg tggcatcttt gatatgacct gccagcgatt tcgcatcctt gctggcttta
    11401 ttcaggaaat tgcgcgcacc gccggacttc ttgttaaact ccgtctgggt ttttgtggcc
    11461 ttctccagat taccgttgag tcgatcgagg ccgtcattaa cagatgctaa cgccgcaacg
    11521 ccatcagtga acgcttttgt aatcccctcc gtaccatccc ggacacgttc tgtctccttt
    11581 gcggcctcgc cgagtccgtg aaccgccccc cgccattgtt caggtaattc gccgagtgct
    11641 ttctggtatt cattgaattt ttccaggaac gactgaaatt tctcgtcctg aacatcaatt
    11701 tcgacaatgg atttagccgc cattgaaata ccccttgcgt cttatttcct ccagaatgaa
    11761 ccgctgccgg aaatggagcg ggcttttata ttcgccgcag cccagttcac ggcagaggtg
    11821 actgaagcct tcgcatgagg cccatgtcag gagggtatgt gtgagggttc cggcagggct
    11881 tccggggtcg gggtatcggt aaccgttttc gacgtcggta aagaatcgcg atacgccata
    11941 gcgctcaatg acacaagttg cccactgtac atatcgagcg ctttccccac cgtcggtgcg
    12001 atcaggttcg ctttctgaat ggcagagctc accataaaaa aaacgacctc gccctcaact
    12061 tcccggtact catcatcggt gataatttcc tgcctgaatg cagcctccag cgaagacgtt
    12121 ttccaggttc cgttatcgtt ccagatgacc gttgtcagac gctgtatctc atcgacaata
    12181 ttcggcgttc ctggctgaag atctcctgcc ttctgccacg ctttgatgat ttttcgcaac
    12241 atcatcgccg ccacgcgggg cgcacctacc gaacccacca gggagaaaaa attattgaac
    12301 agattcccca gcagtacgca attttcctca acgacttcat acgagaacgg cacaacatgc
    12361 agatacacca gtgagccgtc atcgcgggtg atggtgctga caaaattcag ttttcggtca
    12421 attttcacgc ccattagccc cacattttat cgttggtgat cagataaccg gaaatcgtca
    12481 cgacatatcc ggcatccata ccgttgatgg tcagttcatt aaaattcacc agatatgcat
    12541 tcaggaccgt gtagtttccg aaggtgctgg catccggcgt gataacgacc tctcccagcg
    12601 acgtatcaga agcgaaacgg ttctgatagc tcgccgccag cccctgcgtt cgcagtaaat
    12661 gcatcgtgat cgttacctgc tgataaggta cctggctccc cacggttccg gtcagtgtgg
    12721 ggataatgtc cgttgcagcc gaatccggcc gcatactgat cgcatcctta cccagaaatg
    12781 acgcggtgac attcagcgcc ggaatatccg tgacagtcac cgcacccctg acacggttaa
    12841 gaaagccctg cggtactaat ggatttggca tttattacgc ccccacaaaa ttggtcacgt
    12901 tgagattaaa agtgatggac tcaaaaccac gacgcggggt gacaaccgca ctcaggccgt
    12961 tatattttcc atcggcgtaa tcggactgat tcaggctggt atagtcagcg aacggtactg
    13021 cgttgatgac cgcgttcccg gcataagagc ctttttcata ttccgcgttg aacgattcct
    13081 gagtgagttg cgtatcaatc acctgaccaa gaattagccc gtaactgata ccggaacgga
    13141 gagttttcaa agcgcgccgt tgcaggcgac caattccctg ctgatcgtaa taaagcgggt
    13201 taacagtagt gttagaaccg ttaatcactt cattcgccag atccagctca aggttgattg
    13261 cacaccatgc caccgagtac cagtagttaa acggcatacc gtcaagcatg tgaccggcca
    13321 ccagcatttt attgctcagg ccaccttctg ccgccgtgcc gatatagttg atatggttat
    13381 cctgcagggt tttcagcaac gtaccattac ctgccggtgg atactccgtt acgccataca
    13441 taaagcggta cgccatcggc gggaccatgt ttgatgaccc cggatcgttt gccagtgagg
    13501 actggaacgg tgccgccatc gagaactcag ttgcgccaat tgacggcgcc tcaaccccgg
    13561 caaagacatt cggatatttg ccggataccc attcctggta cgtcgcaatc gtggtggtga
    13621 cgaaaaattt caccagcgcg ccgggcgaag tgtaattgtt cgccagcgtt ttaaaggtcg
    13681 gttcggcgtc ccattccctc ggcacaaggt aagagaaaaa tttctggtat gtgtttccca
    13741 gagaagtatc ttcatcaatg aacgtaccaa gggccgcaac cgcagatttt acattcatct
    13801 cacccagctc aaggacataa accgcccggc tggtcccctg tgcccagtac gtggtgttca
    13861 tctgctggag ttctccggcg gcaacagacg ttacggtacc tgtaaccgtt gctgtaccag
    13921 gatcactgtt caggggataa gtaaacgttt tttcgcctgt caccgacgct gtatatgccc
    13981 cgttataagc agcaggcgca gcaccagaaa tcacaacagg gatcgtttca tcaatggacc
    14041 agccatgatt ttctgaaaga gtcaccgtga cggtattccc ggcccacgca agcgaagaaa
    14101 tagcttttgc tggcgcaacg atatttttta gatcgtcttt ggatgtcagc aactgataac
    14161 tccccgccgc cagcgtggtt ccccccgttg ataccagagc gcctgacttt aacaactggg
    14221 agggtttcgg cggactggtc accgacacat tgatatttac tattgccatt tggattattt
    14281 ctccacataa atggacggaa ttgcagacgt gatcagcctg cgggcgacgt tcctcatccg
    14341 ctgctggtag taattaactt tgaatttgac ctttttccgc atggcgataa tgttgagctc
    14401 gttctgcgtg acgcgctcat cctgtatcac aggaatattc attacgccca tttcggcttt
    14461 atcgctgagc gtgtagtcct gcacatagcg cagaaaatcc tcaacggcag cattacgcag
    14521 ccctgtcacg gtgagtgtca cgtcctcaga aaccagttga tactggttct gcttctcgtc
    14581 gagacagaag gctccggcca cagggctcgg ttctccgcat ttcactgtag cgtagggcgg
    14641 cgcaaggttt tgcacggaaa gcattgccgg gtacatcggc atgaaatgac tcagagagag
    14701 ccagatcggt aatgagttgg aaaccaccac atccgcaaga tcgatatcgt cggcagaatt
    14761 aataatctgc gacatcatat gcggataaat ggcatgtccg gtataatggt aaatgttcgc
    14821 tggttcgttc agcccggaac ggcgcgagaa agcaaactga atgccgtaaa actctccgat
    14881 ataaagcacc tcagaaccaa tatcattaaa cggatcaata tcggcttgcg cggtgaaggt
    14941 caccacattt ttatcgtaga gctgttcttc atcctggata gattcagtag tcaggtgcag
    15001 atagcctttt acctcctttg tatccggttc agtatcagga tcatctgcaa gaactgacgc
    15061 cttcacccag aaaacaaagc catcaagggg aagcactttc cggacatatt tagtaaacgt
    15121 aacagatgcc gaacggctga tatcatccag cccctgcacc agcgacgcat tgagttccgt
    15181 tttagcctga gagagttcac tgagggaagg cattcagcac cccacttacc caggcgcgca
    15241 ttgacgcctg aaacataccg gtatcgataa aagagggccg cggttcccct ttcctgtttt
    15301 taaaacgctt gctaatcccc tccagtgcgc gggcagtagg cacaccttct gtgccgttca
    15361 tctcctcgtt atcaaggaaa gcgacaaaga ggtgatgcgc ctgtgacatg gattccgcga
    15421 agggatccgc aggaagcggc gcgcctgcga gcatattttc gagaccggcg gcaaggtcat
    15481 tactcatcat ctgtgcaatt tcctcgccgt ggcggtcaaa gaacgtctgc atgatccggt
    15541 atttcccttc aagaatttcg gccacatcgc cagtagtcgt attctcgttt tcatagggaa
    15601 tatccatcac gcccaggtgc agtttcacgt cagcccccac aaatcgccgt actgctgcgc
    15661 aattgccaga taccaccgac catacgggtc tttgagttgt tgcagatctg caagagagag
    15721 gtttttcagt gcatcactga caacccgcgt ctgactggtt gattcgtcgg aagaggtgct
    15781 gataacgcca gcagtaaaat tgttgatacc cagtttttcg cgtaccggac cgaaagcgac
    15841 ttcaggaccg aagttaagca gaaaggaggc cgcgaggtta taaacagcct gcgaatacag
    15901 aaccgggctg atacaggcga tctgccggtt cacccagtcc agggacattg accaggagag
    15961 actaacggcc ggatcgtcat cggctaacgc gtcggcatta actcccatcg tattacggat
    16021 aaacaggata aatccggcca gttcaggcat gacacacccc gcttattttt tctttttagt
    16081 tcccgtgtta accgccagtg tttcatcaac aaacgctgtt tcgtcacggt catcggtggc
    16141 gttcagtcgc tgctctgcac tgacttccag ctcaccgaga tagccgtttt cctgctcagt
    16201 gagtgcgtta tttgttgcca gtacggaagc ctgacggcga tcgtgcgctg cacggttcag
    16261 gtgaccatcg ttatcccgca tggccttttc gataaccttc gacgacaccg gcttatcaat
    16321 gctgtaacac aacccgatat aaatacggtt ctggtcgatt tttgtcgcat caatcagacc
    16381 ataatcggcg tgctgctgaa taataaggtc gatttcggcg cgggtaccgt caatgacaac
    16441 ggcctgagag cctgcattaa tcgggtgata aacaagacgt cccgtctccg gcttgcgcca
    16501 ggcgaaatcg tggcgctgtt tggtggtgtt ggcgatgtac agtttcatgt ttactcctgg
    16561 gtaaaaaatc cccgcgcacc ctccggcacg cagggaaatc agcgagggaa aattaatcgc
    16621 tgtacttcat cgaaatgata gtcagcgctt cagggcgaag tacccagcca gaggtggaac
    16681 gcagttcgga aagcacatcg atcgccccgc ccgcaatcgg ggtgggaatt tcacgcggtg
    16741 ccgccatgtc gcacagcatc agtgatgtgg cttccagtga cggactcagt ctggcgaatt
    16801 cgttggtgtt gattttcgcg ttaacctcag ggcgctcgac ctccggcatg gcgatgacga
    16861 tcgcatccgt tccgtttgcc ccggcaccaa tcagcgtatc gtcataaccc cattcaattt
    16921 cacaatcagc atcatccccc acaccattaa cggtgccttt caccgtggaa gtaccaccgc
    16981 ccggacgctg gtaactggtc aactgaacga tttgctgcat ttccatggta cccagcgtgc
    17041 gctgaggacc gaggataacc atgcgtgacg cccggcccat ttgcatagtt cgggtgcgga
    17101 tcgcctgaat ctgcgccagc aggaataccg ccatttcgcc atgatcgtaa gtaagtacgg
    17161 tagtgttccc gcggctgtct gccggcaggc tgatagtggt cgcaccgttg gtgttcagta
    17221 ccccctcacc gcccgccggg ttcattccat agagcagcgc gttacgcatt tgctgaaaaa
    17281 tcgcctgccg ggtaccgagt cgctgggctt ccggaagcgc aatcccccag ttccccgctg
    17341 cggccatatc gtgatgatcg taaatggcgc gggcacggaa catatatgtc ggcgtgctga
    17401 ccattcgcgc ctccagtgcc acagagggta actggttggc gttacctgac tggcttgagg
    17461 tgacctgagt gcgaatatcc aggcgtttca tataaacgta ctggtcgccg tctgccaggc
    17521 gaaccagcgg gttaccgctt gccatgacag aaaacgcacc ggatgcctgc tgatacgaca
    17581 ggatcatttc cggcatgatg tacgacggat ttacaatttg ataagcgggt gtaatagctg
    17641 gcatctctta gcctctcctg attacagcag aattaccgca gcgtttccgc tgtcgttcca
    17701 ggtagcaaaa cccgttgccg aatcgtaaga aacggttttg ctgttaccca tctgcatttc
    17761 gatgattttt accggaaggg caacgtcttg cacttttgcc gcgcctaccg ttccctgcgt
    17821 ggttgcattg cccgcaggca ctgaaaccgg ggtaaaggtg aatgtggttg ccgtaggagc
    17881 actgagcacc tgaacaatgc cgttatatgc agcaggagcc gcgcccgtaa tatccacata
    17941 aacgcccact ttcaggccgt gcgcgctggc agccgtcgcg gtcgcaaatc ccgctaaatt
    18001 tgcggtaggc gcagtccagg taatagcggt tgtagccaca tctgccgccg cagtgctgaa
    18061 cacatccaga caatcctccg caaaattcca caccagcggc tgattaacag aaatccccgc
    18121 gctggccaga gagatcacgg catcagaggc tttgaccgga acacgcattc ctgagcccag
    18181 gcgataaaac gacacgctca tattgctgag gagaagcggt accggggatt gcggcgtggt
    18241 caggccgttg tgtgcctggt tgaacacgga aaagcccacc agttgtgaaa ggctggctgc
    18301 gcgtttgata atgctgccac gtggtgcaga agaggcgccc ggtacaagtt cgttaaccgg
    18361 cagtccgccc cacaaaggtt ttatttcatc actggcaagg gtaccggatg ccagcgcata
    18421 acgtgccgcc ggatcgtcca gcgccacgcc ctggataaga ccatcagatt tcgcgtagaa
    18481 cgtgccgcgc gcgttagtgg tctgcattgg attaactgac aatgcactcg ccatatttat
    18541 tgttctccgg ttgattactg tttgatgcca gcgactttgc ggctgacagc ctggaacggt
    18601 gcccatgttg cggacggatc gccgataaag gtactgatac ggcgtccggt ggcgtcggtg
    18661 cggatgactt cacgtaaccc ggcgccgggc tccagactgg atgccgctga tgcctgcgca
    18721 tcggcataga tttttttctc cgcgatgctc aggagttgac tgtctgcaat ggcatgcaga
    18781 tccacttctt tataatcagg agaatatttt tgcagacgtg tcatgatgcg gcggcgatat
    18841 ggcatcgcac gttcacccgc cattggttgc ggcgcacgct ccccgaaaga agcgaataca
    18901 ctgtcggctt tgcactgggt atcagcgatt tcgttacgtt cttcgtcgct gagttcctga
    18961 ggtacacggc ttttcatttc ttccatgtcc gcacggattt tttccagttc agcatcagct
    19021 tttgcctttt cttcggcttc tgcatctgcc ttggctttcg catcagcgtc agctttcgct
    19081 ttttcttcct cttccttgag acgggcagca tcttcatcag ctttcgcctt ttctgctgct
    19141 tcggcatctg ctttcgcttt ttcctcagca tcggcctttg cgcgggcttc gcgagcgtcc
    19201 agcgcctggt taatgagtgc taatactttt tcttcatcca ttttctggac ctcgttcaaa
    19261 agtgtgtcgg atttaactcc catcggttcc cccagcttgt cccagacgcc ctgctcacaa
    19321 atagctaggt gatctagtaa aacaggagtt ccttccagca gtagcggttc gccatcgacg
    19381 tcgatcagaa cgtcatcgcc gcccgtcacc gtgggggatg tactgagttg ccgcgttgaa
    19441 agattcgcgg cggcgtcggt gtcgtaaatg cgggccattc cccacacctc atcaccttta
    19501 atccaggcaa acgtaatcgc cccaatcgtc cttgaggcga attcttcgct attgagtgtg
    19561 tttttttctg gatgccacca gataaccggc aggccagaac accgggcgag aaattcatcc
    19621 gtcaggtaat tttcagggga gcggtaggcg tattgcctga atttggatcg ccatgtaaca
    19681 cccgttccgg tgatacgcag cgcccacagg tacatatttc tgaaaaattg cggggatgtg
    19741 agttgcccgt cggcaataag cccggcaaca tccatttcat tgagtggttc ggcatcaagc
    19801 atcgccacca taccagggtg tagcggatcg ggcagttcat ttggcgaaaa ccagccacat
    19861 gcttgatttt catcgttcaa aaccgcgtcg aattgctcag catcatcagc aaggtaggta
    19921 acatagccat caatcagggt atgaggcgtc agcggtgcgg aataatcaaa cccgcactct
    19981 tccagaactt cacgccttgc cgcggattcc ggcgtttccc cctcttcgag ttttccgccc
    20041 ggtaccgccc acgaaccatc atccccacgc ttaaccagaa atattttccc gccagactta
    20101 aacaggatcc cggcagcgta ggttttcact tatcctccgt tttttatggt ctcgaagttt
    20161 gcagaacgac gaccgactga tttgttgcct tcaatgaatt tccgccattt ttcggttttc
    20221 atttcatcag gcaggcttcg gacgttatag atgaacgtca ggtagcaacg acaaaagact
    20281 tcttcgcccg gttgagtgat ttcatcgaga tagccagccg gaccaacctt catgaatcct
    20341 ttttttatcg cccagttgcc acgaatggca tacaccagca aatcacgctc cttatgaggt
    20401 tcacggaaat cataatttgg ctgtcgccag tggctatgcc agacagcagc aattgcccca
    20461 ccctcagtgg caatgatgtt atcaatgttg gcgataagct tatgcgtctg atcgaccatc
    20521 acccgacgct gctcgaaatc aatctggcgg gctgattttg cgatgtgctg actagtagca
    20581 attacaccag accgggaaga agccgacaga ccaacgctca tttcgcttat cggcgggata
    20641 ctggttgccc acccgctgaa gcgctgaatt gtcttatcaa tggcctgcgt acggttgagt
    20701 tttatcagat cggcggatgc catgatccgg cggtccagct cagcacgaag tttcggctca
    20761 aggtaattta gcgtgaaacg actcacacct agatggcgtt tcagcgcttt ttcccgtccg
    20821 atctccagat cataagctgc agttagccgg cggctgacgt atcggtacag gtcatttcca
    20881 tcaactttgt tttctgtggc attccgcagg cgctcagtcc acatgatcag gctttcttcg
    20941 ctgctgtaac cgtattccag aaaatgttta atggcgtcac gcagctcttt cacgaatgag
    21001 gccatcgtag ttatcctcgt tatcgttgcc tgttggaggt gggtccggag ggcattgctc
    21061 cagcaattcg taatccagct caagccgatc agcaaacagg ttttcgttca tgttggcgtt
    21121 ttcacaggcc catttgatga gcgttgccct gttttgcggg tctttagtga gctgaggcag
    21181 cagcacgttc agcatctcag taatcgcctt aaagcgggtt tcatcaactt tgaccttttc
    21241 gctttcaggc tctttcaacg ctgacggcca gacgtagtcg aaattgttca cccaggaatt
    21301 gaatgccgcc tcccaggtga ttttttcgta ctctggcacg tcgtttttca atgcttcgaa
    21361 aaattcgcgg gaccaggcgc ggtattgcac gatgcgcaca aagaaatcgt aaagcggctc
    21421 aaggtcttta cgaacgtcat cgatgtattg cgctaccgct tttgcatcct cggtaccttc
    21481 gccaaatcca cgtgtgaatg tctcgctgtt aagcagaatg gcaggcatgt ccgccgccgt
    21541 agcgatattc gccaggatgt gattacgggc agtatccagc ggcttttcga ggttctgcat
    21601 atcgagcgat tcaattttgt cattctcacc gacctgtaac acatcgccgt ttccgcctcg
    21661 cttcagcatc cagcgcttaa taccggacat tttctgcatc atattgttga cgatagaact
    21721 ggcctgcttg ataaacgcca ccagcagccc ggctttaatc gttaccatgt catcagcgcg
    21781 catcgactga atgaatgatt tcagcggata gagcgcacgc tgataaacgc tgcgcccggc
    21841 aaaaccgaag gatgacggag tgtaggccag ataaatcgga tcctcgttca tcatcacgca
    21901 gcagcggcta tgatggtaag gttgccccgc agcagtcacg cttcccacct tctggaaatc
    21961 agcagaatta ggatcctgat tgagcaccac agaaccagct gtattcatcg gatccaacac
    22021 gttgaaggtg atggattttt tatacagcgt gtcaaactca gcggcttcgt tcgtgggctc
    22081 gccgtcaatg agcatcacca cagcgcctac accgtaaatt ctggactggc gcgcagtgtt
    22141 agcaatgatg cgatcggctt taattgcttt ccactcgcgc tcgaaagctt cacgcaggcg
    22201 cctttcaggt ccacgagtaa catgtacagt tcgtggttct gacatcgcca gttttatcgg
    22261 gcgatcgacc atctttccgc ccagcgggtg aaacaaataa atcagcttgc agagctcgta
    22321 ccctgcctgc gcgccgggtt caatgcttcc gccctccaga atcttactga ggacgccagc
    22381 attactgccc atgcaaatat cgtcgtcgtc ctgcatcaga acccctctcc gttaccaagt
    22441 ccaagcgcga cgccgtagtt aaagcagtca aacagatcgt cgtcctggtc ttcttcaccg
    22501 atgatgaact tgagcacctg cgtcagaaga tgatttttct tcgattgctt gtactcaacg
    22561 attttgtcaa aggcgtattt agaaatgcgt actttcccgg acgccacata accagaaatg
    22621 ttgatggcgc gggattcttt gggaagtgac gttaaatcac tgtcgatagg gtgtacgttc
    22681 cacccctcat tagccccctg ctgtaacagg gtgatcccgg ttgccttgtc ctcgataaac
    22741 aggcctgtag tccccatacg cgcgcgacat atttcgctaa gctgtttggc ctttccttcc
    22801 cactgaggaa caatgtcttt caggaaatat ccatcaatct ggataatgtc ccagtccaga
    22861 ataacgaggt gtggcgacgg caggttatcc agcgcaaacc agatgcatgc ggatccatcg
    22921 ttctggagtt tccccttctg cgcacagtca acgacgccat aaaccgtatc gcaggaaaat
    22981 gggtagtcga caggagcgcc gtcctccagg atccaatcga gtttgaaaaa gttctgcccg
    23041 cgccagtcca caaattcggc gttatattcc tgctgaacca ccagcggcgg acgaccatca
    23101 ataattcgcg ccagcgcagc cggattaata gtcgggttgg cagcggtcgg tgcgtgatgt
    23161 tcctcccagc ccatcgattt atcgttacag gcctgataga aaaaattctc gtcatcaacg
    23221 cctttaggcg taccggccat tactgcatcg ccatcaaagt cgagcagagt tggctctatt
    23281 gcctgttccc agatatcacg catgcccttc ttaacgaggc ttccctcatc aataatgact
    23341 ttgtggtatt tacgggatcg accagcatca gggttatcca gcgtccagaa ctcgacctgc
    23401 cccccaccaa tggtttcgat aatcgcatcg gtcttactgg aactaatcgt gatcggcttt
    23461 aacaggtcgc gtatagcttt aaacgacggc agcagaattt tataagacgg cgcaaaccag
    23521 cctacgcgca tttgccgcgc tgcccagttc cctcctgcct gctccagcat cgttgtctta
    23581 ccgtaacgac gaccggcacg gataactttt cgttttgcag gagaacgata aattttcttt
    23641 tgccctgcat ggaacggcag gaactcaata acatgttcag tcgccatcag gggaattcac
    23701 cagtttaatg accactgtcg gctcgtcgtc tttgcccttg cctttacgct taagctcaac
    23761 ttcttgttcc agacgttcgg cttcggcggt gcgttttcgg atttccagat ccagcagccg
    23821 ttgcgccagt tcggattcgg taagccccaa acgccgcata atcgcttcaa acattttttc
    23881 gcggctgatg gtcgatattt cgatcccacc tttcacaagc ttggtaccgg agtatgctag
    23941 gcgggctatt gaggatagtt tggttgtgtc agcgaaatac ggcctgccaa ctccatcgcc
    24001 attgcagcga gggcaatcag gattaggatc gcggttgtgg ttgtagccat atccgccagc
    24061 atcgtccggt tctttccctt ttttggcttt tgcctccgct tccctctctt cgaactcgat
    24121 aacatcacgc cattgatagt gatggccaaa gccccagcag taacgacaac atccccggcg
    24181 atattgcgag atttcgttag cgtcgaatgt ggcgagttgc cacatctttt cgagcacttc
    24241 atccgcactc accaaagtgc gcacaagtga atctctttgc tgctgcgcaa ttgcctgcgc
    24301 aacgtgaggt aatgttagga gttgcctacc atagcttgcg tcactgtaac cagctcgctc
    24361 ggctgcggct gtcgcgttct ggtctatgag atattcagca acgaagcgtt tctgttgggg
    24421 agtaagttca ctatcgagaa gtttctctgc gctttttctt gcctgcgcag tgcgcatttt
    24481 tttctgcgca gattgttgcg cattttgcgc agtcggtttt tttatgtagc ggcgggcaga
    24541 tgtgtaattc agtccctgcg cttcacacca gtctttgggg gaaataccgg atttagcatg
    24601 ctcggagagg aactggtgtt gcagtgctcc ccagtccggt tttgccataa ttctgcacct
    24661 gaggttaaaa ccattacaat gggactaccc attgtaatgg caataaaaaa accgcccgga
    24721 ggcggttcag ttatcatctt gataaactaa atcagatcac caatgtattt tgcaccaatt
    24781 gaaatttgca tctgaggcat tccgaccaca gagccattta actggtaatc acgtcctcgt
    24841 tcctgcaatg aaagactcag ttcaaaattc tttacccctg ggaaaaccga ggtgacactt
    24901 aaatcatgct gtgatacgcg cagaataagt tggttacctt caatttttcc ctgatacgta
    24961 aaaccaaaat ccccgccgtt tactgcatcg tttttgacaa ctacggtacc attgccaaaa
    25021 tcccgttgat tacttctgaa aacaacaaaa tagataccat ctttcatggt gtttccttaa
    25081 tcaaataacg aagacgctgg agtcgttcca gtgcgttaca tgaagttgtg ccgggaccat
    25141 tcatattcaa gccggtatat gtgtttattt ttatttattt ggtacgggtc acaaataatt
    25201 tgacccacta ctttgtcact ttgtcgtagg ttcgttcaca ggcgcttcca gcgacataac
    25261 gctcatcagc ctcttttgcg aattttcccg ccagatcgtc agcttcgccg agcagctggg
    25321 cgagcaatat tccggtctcg gcttttgcct ggcttgctgc tgcaatcgcg gaaattctgc
    25381 cggtttcact tgttgcgagt tgccgttgta tttcggcgag ctgctgttgc aacccaccgc
    25441 gagcacgctt agcagcgtca gcatcagcct gtacttttgc cagttcttca tcggctttct
    25501 ctcgttcctt atcaacggcg agctggcggc gctgctcttc tgctctttcg gttacttcac
    25561 gctgcaatgt gatggtcgca tcagtaaggt cacgttgcgc ccactgcaat ttccaggatg
    25621 agtccgcctc ctgatacccg cgtgaataac accagtacgc tgtcgcacat aacaaaaaag
    25681 ccaccagcag tatttctgct aatggcttcc agtattttcg tatcagcgcg agaaccataa
    25741 ttagcctgcc tgttcgacag cgcgatcaaa tgtatcagag ctgtatggtt ggttcccgtt
    25801 ctcgtgctta atgatggctt gtagcaactt aatcatgaag cgactgtcat tggtatcaat
    25861 gcgctggtcg ggagtaacgc ccgtcgcctg agccacgcta ttgatatagg cctgcgtgat
    25921 attctcgttc ggtggtgccc agcgtttgat aatgccgctt accgtgtcca atccatactt
    25981 acgctgataa ttacgcaaga tgataatcat tgcccggatg ccatattcag gagtagtgaa
    26041 ctggcaaaat gatttgtccg ttcgttgatc ttttgggacc aggcctttcc aatcgtcacc
    26101 ccagcgaata tttccggggt tattgttgcg gatcccacgc ggagtcttag ttgtcataat
    26161 cacaccttgt tattgtcgct accgacacca agtcgattgc caattaaccg cattgcaaat
    26221 cctcggatgg catcaacacc aatcagcccg acgccgccac cgatggccac agacagagat
    26281 ttaggccaac cgaaatattc caaagctgat gagaaggtca aagtcagagc gccacaaaga
    26341 agaatttcga gtgttttttt cttccagccg ccaccaccac caaagtaagc gatgcgtaaa
    26401 ccagccatgc ataacgacat gagaacagcg cccagcggcg tatctccgcg ccaccagctc
    26461 tggaataatt ccagccagtc cggccaagta ttggggttat gaggcatttt catgatctct
    26521 cacctcgcgc atattgcggg tgctaattga gggaataaaa aatccccgaa catccaggag
    26581 cggaagcgga gaaaggagtt gcactaaacg gacctttcag cggccttaaa taagaaaacc
    26641 ccgacaaatg ccgaggtccg ttaatcgttg ccgctgtgag tgtcgcggag caggctactt
    26701 gatgcgttaa accgggcgcc aaccgtaact cagtgatgct ttacgcttcc tctccctcac
    26761 tacgtcgcca tgggagcccg accagattaa cgctgtcgtc acgctgccaa aaacatggca
    26821 tccaatacgg tatttccgtt tagctatttc attttcccat cctccagaaa caacaaaacc
    26881 cgcttgatgg cgggttatta atttttatct atcgctgcgg gtgtagcttc gcgagcatag
    26941 ctgaattcaa gcaatccccg cgcaaatttg caaccggaat cgatcagctt ttttatcgaa
    27001 tacatcacac attggtaagt acagcatggc ttctgccatc tgcagccaga catcaattcg
    27061 gctttcgcag gttcgtagac accattccgg atgacgggta ttcagttctc ttgccatagc
    27121 cttcttactc atacgatcct tgtaccgatc aactaccaat ttaaaaagac gctgatgacc
    27181 agtccgaacc aatatttcac cgatcacagc atccattaat aggccttctt catcggtaca
    27241 gaatgccagg ttgctttttt cttttccgga aagcatgtcc agaaaatatg acatcagttc
    27301 accgtgatcc agacctgatg atttgaggtg cttcaacacc tgctgaatgg cagttttact
    27361 gacttttttt gacgcgagaa ggttattaaa catgtgacca cctgagccgg atccaatata
    27421 tgaccatcgg ccccacatac gaagtttacc ctgaatccag actgactcga gggtgtttaa
    27481 tcgcagcatt tccccccctt ttcctgtcgt tgatgggtta atcatataaa cgcctcctct
    27541 ctccagattt gttgggtacg gaaaacacct tcggcgtgat atagcctcag agtgtcctgt
    27601 tcaatatcgg tttttacacg gccatcgatt acgtcatgac aacagttgca ggcaattgcg
    27661 ccttgcatgt catgtggttt gattcccatc ccgcaggtgt cactcatgcg ataatgggca
    27721 agaacgctgg tttctggatc aaaattgcag atacctggaa tgcgcacagt acacatgcga
    27781 ccgcgcgcct gtttggtgag atcgattttc ttcatgcggc gtaactgaat aattgtgagg
    27841 cggcgttttc tgcagcctgc tgggtgggaa atgtgcggaa caaaatataa ttccatagca
    27901 catcaagtac ggatttatag agttgggaaa actcaagatc gtccattttg gcgaacgata
    27961 tggatttggg ttcgttgcgg gtagtaccgt ctggcatttc gtattgagta taaaaacccg
    28021 cctcaatagt tacccaggcg cgaaaggctt caaaggattt tacagcgctg atattaccgg
    28081 cgcgtttttc tgcctcttca cgcagatact gatcggccag ttcctggagt gtttcttcat
    28141 ggccagcata atgggccacc agctgcacat acccacgaac cagtttttta tctgctgggg
    28201 atattgcacc gcccgacggt tgccagtaat cgaaaccaag attcaggagt gcaaaaaatt
    28261 tacggtgaaa tgccgcatta cgtgcctgtt taaagtctgc atataaaaca gcaccaagac
    28321 ggaatttttt ctcgataaat tcccgtgcat caggcgtcgc cggaattaat actccgcctg
    28381 ctgattttac aaatgaatac tgcgccattg gtttcccctt tagcgcagca attgctcaga
    28441 aatacaggtg ccgggtgttc agtccggtac aataattata tcttagtttt gcctctttga
    28501 acaacgacac aacctgcttg ttcagccagc tctaacaaag acttaagcga tgcgacatgc
    28561 tcatcatcat agatttttct gagtgctgtc acctgaccat tcttgcaggt tatgagaaca
    28621 cgaccgttat cggggagttg cttccctatc tccatctttt tgaacacgtc ccctcctgca
    28681 caaaacagct gtataaaaac acagtattta tacatccagg aagcagtcag tgcaaacatt
    28741 aaaaggaatt gcgtgcaaaa aaaacacacc aactttaatg taactaattg tttaataaaa
    28801 taaaaatgag atccactaat gatatgtaag cctgattctc acgtaataaa cgaaaaaact
    28861 gctgatgaac aaatgccacg aggtatctcg accacctcat tacacttttt gcgcaagcat
    28921 atagctagct cgtatcaaaa cgcagcaaat gcctagcaac tgaagcttca gacaaattca
    28981 ccatggacaa tgtgtatcac aaatgccata ttaagggaca ttaaacaaaa aaatgtctaa
    29041 gtgggacgag tatgattaaa tggtatcgtt ttaaaaattt ccattctttc aaagaagagc
    29101 agtttgttga ccttactttg aaggcaaatt cttcagaatc ccctcttgac cagcagtggg
    29161 gtgatgatcg aatagctaaa gttttagctg taatgggtgc aaatggctca ggcaagtcta
    29221 acatgataaa accacttgct tttttaagct ggttttgtag tgattccttt aaatctatgg
    29281 ataactctga ttctttacct atttatccac atatttgcaa taaaagt
//
LOCUS       DAJVKX010000049        29011 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000049 DAJVKX010000000
VERSION     DAJVKX010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29011
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.049"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(50..1258)
                     /locus_tag="OPY25_002191"
     CDS             complement(50..1258)
                     /locus_tag="OPY25_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0927801.1"
                     /translation="MTYRSKVAVVYLLGFFLDLINLFIASVAFPAMSVDLHTSISALA
                     WVSNGYIAGLTLIVPFSAFLSRYLGARRLIIFSLILFSVAAAAAGFADSLHSLVFWRI
                     VQGAGGGLLIPVGQALTWQQFKPHERAGVSSVVMMVALLAPACSPAIGGLLVETCGWR
                     WIFFATLPVAVLTLLLAYRWLNVASTTMASARLLHLPLLTDKLLRFAMIVYLCVPGMF
                     IGISVVGMFYLQNVAQLSPAAAGSLMLPWSIASFVAIMLTGRYFNRLGPRPLIIVGCL
                     LQAAGILLLTNVTPATSHRVLMMIFALMGAGGSLCSSTAQSGAFLTIARRDMPDASAL
                     WNLNRQLSFFLGATLLTLLLNALQRVMSLEVAYRWTFIAAAGITLLPLIYAVCLNNRQ
                     ALLCLKKERS"
     gene            1346..2278
                     /locus_tag="OPY25_002192"
     CDS             1346..2278
                     /locus_tag="OPY25_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0927802.1"
                     /translation="MTVKELAMLNLQRMSLFVAVVDSGSFTAAAAASGQTKAVVSFNI
                     RQLEKELGVTLLLRSTRRLTLTDAGVLFYQKGVNLLNAAKNLQDEVRASHSGLGGELR
                     ITTTPEFGEQVVIPVLAQFSQRHPDLRIRHMSSSHHADLIAERFDVAIRLGSLADSRY
                     RAALISRFTILPVAAPQWLARHPVSSLESLAQAEWIIHERLPTPLRWTVTNNHGQHSR
                     LEISKAGKISVDSARSLMAFALAGSGVALLPQWLVNTALEDGTLIHVLPDYHFPRQGI
                     YAVYPDARHVSTKVRAFIDFLRSQWDCGEHAPSL"
     gene            complement(2320..3816)
                     /locus_tag="OPY25_002193"
     CDS             complement(2320..3816)
                     /locus_tag="OPY25_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCS0927803.1"
                     /translation="MTSLPTPIIGLIVAVFVLVWLVLRTRVHALIAMLAAACIAGLLG
                     GMGIDKTLSVITSGFGTTLGSIGLVIGLGVMMGRLLEVSGAAERIAWSFIKWLGKRRE
                     EWALAITGYIVSIPIFVDSAFVILYPVAKALAKSGKRSLLTLGVALAGGLVVTHHTVP
                     PTPGPLGVAGIFNVDIGAMLLTGMALAVPCVIGIVFYAQWLDKRYPDFVPRTLNADEV
                     NAALEQYNKEKEQKDLPSLTLSLLPIVVPIVLIFLKAICSTLATVEGWSGLATHPVVQ
                     AINFVGSPVIALAISVLLAVYTLVPRMDKHTTAERLEEGLQSAGIILLVTGAGGALGA
                     ILRDSGAGQQLAEQVANLPISPILIPFIVATLVRLIQGSGTVAMITAASISAPILAQI
                     PGINMLLAAQAATMGSLFFGYFNDSLFWVVNRMMGVSDVKQQMVVWSVPTTIAWAIGG
                     TGVALINLLFGSGGSWLDPLLPIVVLAAIMLWVRWQAQGIKDKLVVKD"
     gene            complement(3813..4763)
                     /locus_tag="OPY25_002194"
     CDS             complement(3813..4763)
                     /locus_tag="OPY25_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCS0927804.1"
                     /translation="MQIIITGGGGFLGQKLASALLNSSLAFNELLLVDLKMPARLSDS
                     PRLRCLEADLTQPGVLENVITANTSVVYHLAAIVSSHAEDDFDLGWKVNLDLTRQLLE
                     ACRRQPQKIRFVFSSSLAVYGGTLPECVTDTTALTPRSSYGAQKAACELLVNDYTRKG
                     YVDGLALRLPTICVRPGKLNRAASSFVSAIIREPLQGETTICPVSESLRLWISSPATV
                     IHNLSLAATLPAPGEASSINLPGISVTVGEMLETLRQAGGQAARDRVTHQRDEGVEKI
                     VASWPGRIDNQRALALGFVADKRFDDIIERFRQDDMEGRS"
     gene            complement(4803..5579)
                     /locus_tag="OPY25_002195"
     CDS             complement(4803..5579)
                     /locus_tag="OPY25_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HCS0927805.1"
                     /translation="MPRFAADLSMMFTEVPFIERFAAAAEAGFQAVEFLFPYGFAASE
                     IKAQLSRHDLTLALFNTSAGDTAAGEWGRAALPGREHDARADIDLALEYALALECEQV
                     HIMAGVVPDGADGARYRATFIDNLRYAAGRFAAHDKRILIEALSPGVKPGYLFSSQYQ
                     ALGIAEEVDRPNVFIQLDTFHAQKVDGNLSHLIREYAGRYAHVQIASLPDRHEPDDGE
                     INYPWLFRLFDDVGYCGWIGCEYQPRNTTQEGLGWFNAWR"
     gene            complement(5584..6222)
                     /locus_tag="OPY25_002196"
     CDS             complement(5584..6222)
                     /locus_tag="OPY25_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HCS0927806.1"
                     /translation="MTILAKEEHALREEMVRIAASFFQRGYATGSAGNLSLLLPDGNI
                     LATPTGSCLGNLDPQRLSKVDPQGEWLSGDKPSKEVRFHLALYRNNPCCKAVVHLHST
                     WSTALSCLEGLDPQNVIRPFTPYVVMRMGDIPLVPYYRPGDDRIARDLAALAARHQAF
                     LLANHGPVVCGENLQEAANNTEELEETAKLIFILGERPIRYLTTEEIAQLRR"
     gene            complement(6219..7004)
                     /locus_tag="OPY25_002197"
                     /pseudo
     CDS             complement(6219..7004)
                     /locus_tag="OPY25_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461838.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxo-tetronate kinase"
     gene            complement(7095..7520)
                     /locus_tag="OPY25_002198"
     CDS             complement(7095..7520)
                     /locus_tag="OPY25_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCS0927807.1"
                     /translation="MIMTTGTDFHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQAC
                     ANLLAEGACGAAASAREFAGVVDALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVS
                     STISSADAQEIAAALTALNLNMLDAPVSGGAVKAAQGGR"
     gene            7711..8475
                     /locus_tag="OPY25_002199"
     CDS             7711..8475
                     /locus_tag="OPY25_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0927808.1"
                     /translation="MIPTERRQIILDMVAEKGIVSIAELTERMHVSHMTIRRDLQKLE
                     QQGAVIQVSGGVQSSTRVAHEPSHQIKTELATPQKAAIGKLAASLVQPESCIYLDAGT
                     TTLAIARQLVTMNKLTVVTNDFVIADYLMDNSGCTIIHTGGAVCRENRSCVGEAAATL
                     LRGLMIDQAFISASSWSVRGISTPAEDKVTVKRAVASASRQKILVCDATKYGQVATWL
                     ALSLAEFNQIVTDDGLPESAIRALAKVDISLLMAKQ"
     gene            complement(8494..8898)
                     /locus_tag="OPY25_002200"
     CDS             complement(8494..8898)
                     /locus_tag="OPY25_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCS0927809.1"
                     /translation="MELRNTAFHLLRQLFQQHTARWQHELPELTKPQYAVMRVIAEHP
                     GIEQVDLTEAAVSTKATLAEMLSRMENRGLVKRENDPLDKRRRFVYLTVQGQTLLAAA
                     IPLGDRVDDEFLGRLSAEEREQFTQLVRKMMT"
     gene            9069..9662
                     /locus_tag="OPY25_002201"
     CDS             9069..9662
                     /locus_tag="OPY25_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCS0927810.1"
                     /translation="MRLIVGMTGATGAPLGVELLQALRAIPDVETHLVMSKWAKTTIE
                     LETPYTPAEVAALADYCHSPADQAATISSGSFRTDGMIIIPCSMKTLAGVRAGYADGL
                     VGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAIVPPMPAFYNLPQTVDD
                     IIQHIVARVLDQFGLEHTRARRWQGLRQAANFSQENG"
     gene            9662..11089
                     /locus_tag="OPY25_002202"
     CDS             9662..11089
                     /locus_tag="OPY25_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCS0927811.1"
                     /translation="MAFDDLRSFLHALDQQGQLLKISEEVNAEPDLAAAANATGRIGD
                     GAPALWFDNIRGFTDARVAMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFPVA
                     PERRANPGWAENTVDGDAINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQ
                     NVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATP
                     LKYDQSEYEMAGALRESPYPIATAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFT
                     GHYSGGRNMTVVRIDKVSYHSKPIFESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFP
                     EVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFN
                     LPQVMWALSSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHY
                     SQPVVDLPETKAWAEKLTAMLANRK"
     gene            11100..11336
                     /locus_tag="OPY25_002203"
     CDS             11100..11336
                     /locus_tag="OPY25_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927812.1"
                     /translation="MICPRCADAHIELMATSPVKGVWTVYQCQHCLYTWRDTEPLRRT
                     SREHYPQAFRMTQKDIDDAPMVPSIPPLLAEDKR"
     gene            complement(11381..12373)
                     /gene="rpoS"
                     /locus_tag="OPY25_002204"
     CDS             complement(11381..12373)
                     /gene="rpoS"
                     /locus_tag="OPY25_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HCS0927813.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEAFDEKALSEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(12436..13557)
                     /gene="nlpD"
                     /locus_tag="OPY25_002205"
     CDS             complement(12436..13557)
                     /gene="nlpD"
                     /locus_tag="OPY25_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HCS0927814.1"
                     /translation="MSAGSPKFTVSRIAALSLVSLWLAGCTSSSNPPAPVTSVDSGSS
                     SNTNSGMLITPPPKMGATPQQAPQIQPVQRPVTQPMQTQPVTEQPVQMENGRIVYNRQ
                     YGNIPKGSYTGGSTYTVKKGDTLFYIAWITGNDFRDLAQRNSISAPYSLNVGQTLQVG
                     NASGTPITGGNAITQADAAQQGVVTRSAQNSTVAVASQPTITYSEGSGEQSANKMLPN
                     NKPAGTVVTAPVTAPTVSTTEPNASSTSTSAPISAWRWPTDGKVIENFGASEGGNKGI
                     DIAGSKGQAIVATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEV
                     KAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(13733..14359)
                     /locus_tag="OPY25_002206"
     CDS             complement(13733..14359)
                     /locus_tag="OPY25_002206"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase"
                     /protein_id="HCS0927815.1"
                     /translation="MVSGRVQALLEQLRAQGIRDELVLNALAAVPREKFIDEAFEHKA
                     WENIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVHHVCS
                     VERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMA
                     QLDEGGILVLPVGDEQQFLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(14353..15114)
                     /gene="surE"
                     /locus_tag="OPY25_002207"
     CDS             complement(14353..15114)
                     /gene="surE"
                     /locus_tag="OPY25_002207"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HCS0927816.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNV
                     PDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVD
                     EGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW"
     gene            complement(15095..16144)
                     /gene="truD"
                     /locus_tag="OPY25_002208"
     CDS             complement(15095..16144)
                     /gene="truD"
                     /locus_tag="OPY25_002208"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HCS0927817.1"
                     /translation="MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHI
                     LLRILKNGCNTRFVADVLAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFS
                     AFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYF
                     GAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQ
                     VVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQ
                     DAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVV
                     RELINTMGDYAHIAE"
     gene            complement(16141..16620)
                     /gene="ispF"
                     /locus_tag="OPY25_002209"
     CDS             complement(16141..16620)
                     /gene="ispF"
                     /locus_tag="OPY25_002209"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HCS0927818.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK"
     gene            complement(16620..17330)
                     /gene="ispD"
                     /locus_tag="OPY25_002210"
     CDS             complement(16620..17330)
                     /gene="ispD"
                     /locus_tag="OPY25_002210"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HCS0927819.1"
                     /translation="MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHA
                     LLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWV
                     LVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQEKA"
     gene            complement(17349..17660)
                     /gene="ftsB"
                     /locus_tag="OPY25_002211"
     CDS             complement(17349..17660)
                     /gene="ftsB"
                     /locus_tag="OPY25_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HCS0927820.1"
                     /translation="MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNA
                     KLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTH
                     R"
     gene            complement(17851..18174)
                     /locus_tag="OPY25_002212"
     CDS             complement(17851..18174)
                     /locus_tag="OPY25_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HCS0927821.1"
                     /translation="MRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFL
                     LYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALF
                     IWLLG"
     gene            complement(18225..18830)
                     /gene="cysC"
                     /locus_tag="OPY25_002213"
     CDS             complement(18225..18830)
                     /gene="cysC"
                     /locus_tag="OPY25_002213"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HCS0927822.1"
                     /translation="MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLI
                     VLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFT
                     GIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS"
     gene            complement(18817..20256)
                     /gene="cysN"
                     /locus_tag="OPY25_002214"
     CDS             complement(18817..20256)
                     /gene="cysN"
                     /locus_tag="OPY25_002214"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HCS0927823.1"
                     /translation="MNTILAQQIASEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSA
                     NMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNPDFRGYAGTLASGSVKVGE
                     RIKVLPSGVESSVARIVTFDGDKEEVCAGEAITLVLNDDIDISRGDLLLAANETLAPA
                     RHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAICYQIDINNLTQRDVESLPLNG
                     IGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSA
                     FELELNALVRRHFPHWDARDLLGDKHGAA"
     gene            complement(20266..21174)
                     /gene="cysD"
                     /locus_tag="OPY25_002215"
     CDS             complement(20266..21174)
                     /gene="cysD"
                     /locus_tag="OPY25_002215"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HCS0927824.1"
                     /translation="MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVST
                     TSERQGRMIDRDQAGSMELKKRQGYF"
     gene            21425..22471
                     /locus_tag="OPY25_002216"
     CDS             21425..22471
                     /locus_tag="OPY25_002216"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCS0927825.1"
                     /translation="MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFF
                     PGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIA
                     AHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKD
                     IPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLNNLIVGDKLYFNSGK
                     NTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSV
                     EATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIM
                     LPLVKELAKAEKTS"
     repeat_region   22486..22880
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=22547..22575
                     /rpt_unit_seq="cggtttatccccgctggcgcggggaacac"
     gene            complement(22965..23258)
                     /gene="cas2"
                     /locus_tag="OPY25_002217"
     CDS             complement(22965..23258)
                     /gene="cas2"
                     /locus_tag="OPY25_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2"
                     /protein_id="HCS0927826.1"
                     /translation="MSMLVVVTENVPPRLRGRLAVWLLEIRAGVYVGDVSAKIREMIW
                     QQVSVLADEGNVVMAWATNTESGFEFQTFGVNRRIPVDLDGLRLVSFLPVENQ"
     gene            complement(23261..24178)
                     /gene="cas1e"
                     /locus_tag="OPY25_002218"
     CDS             complement(23261..24178)
                     /gene="cas1e"
                     /locus_tag="OPY25_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1"
                     /protein_id="HCS0927827.1"
                     /translation="MSWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGVRTHI
                     PVGSVACIMLEPGTRVSHAAVRLAATVGTLLVWGGEAGVRVYASGQPGGARSDKLLYQ
                     AKLALDEDLRLKVVRKMFELRFGEPAPSRRSVDQLRGIEGSRVRATYALLAKQYGVKW
                     QGRRYDPKDWEKGDVINQCISSATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYD
                     IADIIKFEIVVPKAFEIARRNPAEPDRDVRIACRDIFRSGKTLAKLIPLIEDVLAAGE
                     IQPPLPPEDSHPIAIPLPVALGDSGHRST"
     gene            complement(24178..24882)
                     /gene="cas6e"
                     /locus_tag="OPY25_002219"
     CDS             complement(24178..24882)
                     /gene="cas6e"
                     /locus_tag="OPY25_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HCS0927828.1"
                     /translation="MYLSRIQLRFNNLRPEMLAKWNSARPYASHQWLWQLFPEQELRQ
                     FLFREEAHGGFFMLSAIPPLLQHSLFLIETKLFNPQLTNGLELDFQLRANPVITRNGK
                     RSDVMMNAKHQAKANGVEKERWWELQQQAAQAWLEQQGQQHGFRLIAPEPDDFAMWAG
                     DEYSELQAHCGCVQAYQQHRFVRKDQETPITFSSVDFSGALCITDAALFKQALFSGLG
                     KSKALGCGMLMVKRKR"
     gene            complement(24882..25607)
                     /gene="cas5e"
                     /locus_tag="OPY25_002220"
     CDS             complement(24882..25607)
                     /gene="cas5e"
                     /locus_tag="OPY25_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000666428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HCS0927829.1"
                     /translation="MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAAL
                     GIRRDEEARLNNFNRHYHLAVHALASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLA
                     SDEVGTLISQREYRCDGYWHVAISATPDAPYSLSELREALLTPHFPLYLGRKSCPLAL
                     PLAARLMTGTLKEVFTHAVEEISAAELSGFTLREGICYWDDPDEESLVWQQKQHSNNQ
                     PVSRQRWQFGGYTRFNGPLQERT"
     gene            complement(25617..26675)
                     /gene="cas7e"
                     /locus_tag="OPY25_002221"
     CDS             complement(25617..26675)
                     /gene="cas7e"
                     /locus_tag="OPY25_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001804435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HCS0927830.1"
                     /translation="MTTFIQLHLLTAYAPANLNRDESGRPKTAFMGGVERLRVSSQSL
                     KRAWRVSETFEAAMDGFMGKRTRRIGVDYVYRPMKDAGIEEKIAKSSSELIAKQFGKL
                     KSDKDAKPEKNLEIEQIVHVSNHEISLIKQLVDTLIADKREPNDEEVKLLRKEQRSVD
                     MALFDRMLASSPEFNVEAACQVSHALGVSAVTVESDFFTAVDDLNNKEEDAGSGHMGE
                     QGFASALFYTYVCISRDLLVENLGGNEELAKRTIAALTETALTVSPTGKQNSFASRAY
                     ATYALAEVGQKQPRSLAAAFFQPVRDTDQIPAAITRLKQQRASFDSVYGNCADDYREL
                     NVQEGTGSLAELLAFVSQ"
     gene            complement(26698..27300)
                     /gene="casB"
                     /locus_tag="OPY25_002222"
     CDS             complement(26698..27300)
                     /gene="casB"
                     /locus_tag="OPY25_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HCS0927831.1"
                     /translation="MLNSNTAVLCRILHPDAQKALLDWFATLSERYERKDGKRVNGRA
                     WRAELKRMAPPYGVMICEGHDALRQALLKHMRLQPLDEMALALFVSVAVHIKSHKENI
                     SFAAQLGEKLKGSTSCVSGLRFERLQKASDPETFCQLLIQAVKIRGTEGVNVLSLADG
                     IFLWMEEWQRRENHQPEFRNPFERSRIRWANEYLSTSRGK"
     gene            complement(27317..28852)
                     /gene="casA"
                     /locus_tag="OPY25_002223"
     CDS             complement(27317..28852)
                     /gene="casA"
                     /locus_tag="OPY25_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HCS0927832.1"
                     /translation="MDLTKEKWLPVIFSNGDKKKISLRDLLDNRIQDLAYPRADFQGA
                     AWQMLIGILQCTVAPEDKEEWADIWHESIEFEQWEKALNTISLALQFGEQKPSFLQSF
                     DPLDSEYGSIAGLLVDAPGGNALKLNKDHFVKRGNVEQICPHCAAIALFAIQTNSPAG
                     GAGYRVGMRGGGPLTTLVVPQEEDKYPLWKKLWLNVLPQEEPPNVTQHPLIFPWLAPT
                     KTSEKAGNVVTPDNAHPLQAYWGMPRRIELDFTHTVAGICDLCGEHHESLLLQMRSKN
                     YGVQYDSWLHPFSPYRQALKDPSAPWLAFKGQPGGLSYKDWLGLMLNREDKFNKMQPA
                     KVVRAAGQRNKMSLWCFAWDMNKAKVRCWYQHRIPLISVSHEEQFLAALNIVLVLASE
                     SLSLLRNALKSAKFDCPKEAKMDFSMVDIAFWQETEPAFRTLQEALAVDPLRQDTQTR
                     HAVSQWEAELAHYLFHVFDRDALTNPDCPDDILQRQLTARQDLASSYRKHKARKDVLA
                     LVE"
BASE COUNT         6918 a         8244 c         7378 g         6471 t
ORIGIN      
        1 cagttctcaa tcgccgcatg ggcatgaata atttcttctt tatatggatt catgatcttt
       61 cctttttcag gcacagaagc gcctgtctat tgtttagaca gacagcgtaa ataaggggca
      121 gcagggtgat accggcggcg gcaataaagg tccagcgata agcaacctca agcgacataa
      181 cgcgctggag cgcgtttaac agcagcgtca acagcgtcgc gccaaggaaa aagctaagct
      241 gacgattaag attccatagc gcgctggcgt caggcatgtc ccggcgagca atagtcagga
      301 aagcgccact ctgcgcggta ctgctgcaca aactgccgcc agcgcccatt aaggcgaata
      361 tcatcatcag tacacgatgc gatgtcgcag gcgtaacgtt agttaaaagc agtatccctg
      421 cagcctgaag aagacagccg acgataatca gcggacgcgg cccaagccga ttgaagtaac
      481 gtccggtaag cataatggcg acaaatgaag cgatcgacca ggggagcatc agcgaccccg
      541 ccgccgcagg cgatagctgc gcgacgttct gtagataaaa catcccgacc acgctgatac
      601 caatgaacat acccggcaca cacagataga cgatcatggc aaaacgcagc agcttgtccg
      661 tcaacaacgg cagatggagc aatcttgctg acgccattgt cgtcgaagcg acgttcagcc
      721 aacgataagc gagcaataaa gtgagaacgg ccaccggcag cgtggcaaaa aatatccagc
      781 gccagccgca cgtttccacc agcagcccgc caatcgcagg cgaacatgcc ggcgccagta
      841 gcgccaccat catgacgacc gatgacacgc cagcgcgttc atgcggttta aactgttgcc
      901 aggttaacgc ctgaccaacc gggatcaata agccaccgcc cgccccctgc acaatacgcc
      961 agaaaacaag gctgtgtaag gaatcggcaa aacctgcggc agcggcggca acgctaaaca
     1021 gaatgagcga aaatatgatc agccgtcgtg cgccgagata acgtgaaaga aacgcgctaa
     1081 acggaacgat cagcgttaat cctgcgatat aaccgttact cacccatgcc agcgccgata
     1141 tggacgtatg cagatccacg gacatcgcag gaaaagccac gctggcaata aacagattaa
     1201 tcagatcaag aaagaagccg agcaggtaaa ccactgccac tttactgcga tacgtcatta
     1261 tgcatcctcc gtcagaggcg ctaatgtagc cgtccggaga aagccagata agtccgcgct
     1321 tcaacgatat actgtcaaaa taattttgac agtaaaggag ctcgccatgc tcaatttgca
     1381 gcgtatgtcg ctgtttgtcg ccgtggtaga tagcggcagc ttcacggcgg cggccgccgc
     1441 atcgggccaa acaaaagcgg tagtgagttt taatattcgg cagcttgaaa aagagcttgg
     1501 cgtaacgtta ctgctacgtt ccacccgacg actgacgctc acagacgccg gcgtcctctt
     1561 ttaccaaaaa ggcgtgaatt tactcaatgc agcgaaaaat ttgcaggatg aagtgcgtgc
     1621 cagccatagt gggctgggcg gcgagttacg tattaccact acgcccgagt ttggcgaaca
     1681 ggtggtcatt ccggtactgg cgcagtttag tcagcgccat cccgatctcc gtattcggca
     1741 tatgtcctca tcacatcatg ccgatttaat tgccgagcgc tttgatgtgg cgattcggct
     1801 tggctcgctg gcggactccc gctatcgcgc cgcgctgata tcccgcttta ccattctgcc
     1861 ggtcgccgcg ccgcagtggc tcgcccgcca ccccgtgtcg tcactggagt cgttggccca
     1921 ggcggaatgg attattcatg agcgattacc tacgccgcta cggtggacag taacgaataa
     1981 tcatggccaa cactcacgcc tggagataag caaagccggc aaaatttctg tcgacagcgc
     2041 gcgctcgctg atggccttcg ctctcgcggg aagcggcgtc gcattactgc cgcaatggtt
     2101 agtcaacacc gcactggagg atggaacgtt aattcacgtg ttacccgact atcattttcc
     2161 ccgtcagggc atttatgccg tttatccaga cgcccgccat gtatcgacaa aagtacgcgc
     2221 atttattgat tttttacgtt cgcaatggga ttgcggggag cacgccccat cattgtagcc
     2281 agcccgggag cattgcgctc ccggacggat aataccgtct taatccttaa ctaccagttt
     2341 gtctttgatc ccctgcgcct gccaacgcac ccacagcata attgccgcca gaacgacgat
     2401 tggcagtaac ggatcgagcc aactgccgcc ggaaccaaac agcaggttaa tcagcgccac
     2461 gccggtgccg ccaatcgccc aggcaatggt cgtcggtaca gaccaaacca ccatctgctg
     2521 tttgacatca gagacgccca tcatgcggtt aaccacccag aacaggctat cgttgaagta
     2581 gccgaaaaac agcgacccca tcgttgcggc ctgagcggca agcaacatat tgatgccggg
     2641 gatctgcgcc aggatcggcg cggaaatcga ggcggcagtg atcatcgcca ccgtccccga
     2701 tccctgaatc agacgtacca gcgtcgccac gataaacggg atcaggatcg gcgagatcgg
     2761 caggttggca acctgctccg ccagctgttg ccccgcgccg ctgtcgcgca ggatcgcgcc
     2821 caacgcgccg ccagcgcccg tgaccagtaa gataatcccg gcgctttgca agccctcttc
     2881 cagacgctct gcggtggtat gtttatccat gcgcggcacc agcgtataca ccgccagcag
     2941 aacgctgatg gccaacgcga tcactggact tcccacaaag ttgattgcct gtaccaccgg
     3001 atgcgtcgcc aggccggacc atccttctac agtggcgagg gtggaacaga tagccttcag
     3061 gaagatcagc acgatcggca ccacaatagg cagcagagag agcgtcaggc tcggcagatc
     3121 cttttgctct ttctctttat tgtactgctc cagcgcggca ttaacttcat cggcgttcag
     3181 cgtgcgcggc acgaaatcag ggtagcgttt atccagccac tgcgcataga acacaatgcc
     3241 gatcacacag ggcaccgcca gcgccatccc ggtcaataac attgcaccga tgtcgacgtt
     3301 aaaaatcccg gctaccccca gcggaccggg cgtgggaggt accgtatggt gagtgaccac
     3361 cagcccgccc gccagcgcga cgcccagcgt cagtagcgaa cgtttaccgc ttttcgccag
     3421 cgctttcgcc accggataaa gaatgacaaa agcggaatcg acgaaaatgg ggatgctgac
     3481 aatataaccc gtgatcgcca gcgcccactc ttcacggcgt ttccccagcc atttgataaa
     3541 gctccaggcg atacgctccg ccgcgccgga aacctccagc aagcgcccca tcattacgcc
     3601 gagaccaatc accaggccaa tgctgcccag cgtcgtaccg aatccgctgg tgatgacaga
     3661 gagcgtttta tcaatgccca ttccccccaa cagaccggcg atgcaggccg ccgccagcat
     3721 cgcgatcagc gcatgaacac gggtgcgtaa caccagccat accagcacga aaacggcaac
     3781 gatcaggccg ataattgggg tcggtaaact tgtcatgacc tcccctccat atcatcttgt
     3841 cgaaagcgtt cgataatgtc atcgaagcgt ttatcggcga caaaacctaa cgccagcgca
     3901 cgctggttat cgatacgtcc cggccaggag gcgacaattt tctcgacgcc ttcgtcgcgc
     3961 tgatgcgtaa cccgatcgcg cgccgcctga ccgcccgcct gacgcaacgt ttccagcatc
     4021 tcgcccacgg ttacgctgat cccgggtaag ttgatgctgc tcgcctcgcc aggcgcgggt
     4081 aacgttgcgg ccagcgacag gttatggatc accgtcgccg ggctggaaat ccacagccgc
     4141 aaactttccg acaccggaca gatggtcgtc tcgccctgca acggttcacg aataatcgcg
     4201 ctgacaaaag aagaagcggc gcggtttagt ttacccgggc gaacacagat cgtcggcaaa
     4261 cgcagcgcca gcccatccac atagcctttg cgggtatagt cgttgaccaa cagttcacag
     4321 gcggccttct gcgcgccata agacgagcgc ggcgtgagcg cggtggtatc ggtgacgcat
     4381 tccggcagcg taccgccata aacggcaagc gagctggaga agacaaaacg aattttctgc
     4441 ggttgccgac gacacgcctc aagtaactgg cgggtaagat ccaggttaac tttccatccc
     4501 agatcgaaat cgtcttccgc atgactgctg acaatcgcag cgagatgata aacaacagag
     4561 gtattagcgg taatcacatt ctccagtacg cccggctggg ttaagtcagc ttccaggcag
     4621 cgtaaacgag gggaatctga taaccgtgca ggcattttta aatcaacaag aagcagttcg
     4681 ttaaacgcca gcgatgagtt taataaggcg cttgcgagtt tctggcctaa aaagccgccc
     4741 ccgccggtaa tgataatctg catccggatg tcctctttat tgttgtgtag ggtagttcag
     4801 ggttagcgcc aggcgttaaa ccagccaagc ccctcctgag tggtattccg tggttggtat
     4861 tcgcagccta tccagccgca ataacctacg tcatcgaaca gccggaacag ccacgggtag
     4921 ttgatctcgc catcatccgg ttcatgtctg tccggtagcg aggcgatttg tacatgggca
     4981 tagcggcccg cgtactcgcg aatcaggtga ctcaaattgc catccacttt ttgcgcgtgg
     5041 aaagtgtcga gctggatgaa tacatttggg cggtcaacct cttctgcgat gcccagcgcc
     5101 tgatattggc tggaaaagag gtagccgggt ttaacgccgg gactcagcgc ttcgatcaaa
     5161 atacgtttat cgtgggcggc aaaccggccg gcggcataac gcaaattatc gataaacgtg
     5221 gcgcgataac gtgcgccatc agcgccatcc ggcacgacgc ccgccatgat gtgaacctgc
     5281 tcgcattcca gcgccagagc gtattccaga gccagatcaa tatcggcgcg cgcgtcgtgt
     5341 tcgcgccccg gtagcgcggc acgtccccac tcgcccgccg cggtatcacc cgccgaagta
     5401 ttaaacagcg ccagcgtcag atcatgacgc gatagctggg ctttaatctc gctggcggca
     5461 aagccgtagg ggaacagaaa ctcaacggcc tgaaaaccgg cttcggcagc agcggcaaaa
     5521 cgctcgataa acggcacttc ggtaaacatc atcgacaaat cggcggcaaa acgcggcatc
     5581 gggttatctc cttaactgcg caatttcttc ggtggttaaa taacgaatcg ggcgttcgcc
     5641 aaggataaaa atcagctttg ccgtctcttc cagctcctcg gtattattag cggcttcctg
     5701 caaattctcc ccgcacacga ccggcccatg attagccagt aaaaaggcct gatgccgggc
     5761 cgccagcgca gccaaatcgc gagcaattcg gtcatccccc gggcgatagt agggaaccag
     5821 cggaatgtct cccatccgca tcaccacata gggggtaaac gggcgaatca cattttgcgg
     5881 gtccagccct tcgagacagg aaagcgccgt tgaccaggtg ctgtgcagat gtaccacggc
     5941 cttgcagcaa gggttattgc gatacaacgc cagatgaaaa cgcacctctt tagacggttt
     6001 atcgccgctg agccattcgc cttgcgggtc cactttggat agccgctgcg ggtcgagatt
     6061 acccagacac gaaccggtgg gcgtcgccag aatattgccg tccggcagta acagcgagag
     6121 gttgcctgcc gagccggtgg catagccgcg ctggaaaaac gaggcggcta tcctgaccat
     6181 ctcttctcgc aaagcgtgct cttcttttgc cagtatcgtc atacctgaaa ctccctttga
     6241 gcgcggatga aaaaggattc atcgccaaaa ttacctgact ttagcgccag cgagactggc
     6301 gcatggagcg cgttgaccca cggcacgccg ggtgaaatgc acggtccaat gtggaaaccg
     6361 gtaataccga ggctttgcgt caccacgccc gaggtttcgc cgcccgccac aataaaccgg
     6421 gtgataccgc cttccgctaa gcgagcggcc agcagggaaa agagcgcctc taccgcatag
     6481 ctggcttcgg tagcgccata ttgctgctgg atggcagcca gcgcctgcgt ggaggcggtg
     6541 gcgctaatca ttggcgccag ttcgctgtcc tgactgaaca cccactgcgc cagcgcttcg
     6601 gcgtaggcct cgcgcgcctc ggatgacagg cagcgcgcca cgtcaacgtc gcgtgtggga
     6661 gcatgttgtc gatagaaagc cacctgctga ttcgtcattt gcgaacagga accggaaagc
     6721 actaccgcgc gaccgctcag cggatagcct gcggaacggg cctgagaaac gccgtgcttc
     6781 gcccactgac gcgccagccc cattgccagc ccggaaccgc cggtcaccag cggggcatca
     6841 cgcaaaacct cgccctggat ttccaggtgc cgctcattga gcgcgtcaag taccgcgtag
     6901 cgatatcctt cctgctgtaa acgcgacagc gccgcacggg tcgcggcaac gccttcatca
     6961 agcgtctgag ccggaataac gccgcagcgc ccttgcgcct gcgcccggtg tatcgctgat
     7021 gcgataaacg ttgctggcaa cggcgtccag cacaggcttc aggcgggtaa acgccgcctc
     7081 gcgcccggag gccatcaccg tccgccctgc gccgctttta ccgcgccgcc ggaaaccggc
     7141 gcatccagca tgttaagatt caatgccgtc aacgccgcgg cgatctcttg cgcgtcggcg
     7201 cttgagatcg tagacgaaac catcaccgcg cttccgggtt tcatcagatg ggcgacgcca
     7261 tcctcaccga ataacacctg tctgacctgg gcggcattga cgaccagaat gactaacgca
     7321 tccacgacgc cggcgaactc cctggcgctg gcggcagccc cacaagcccc ttcagcgagc
     7381 agattcgcgc acgcttgcgg gttaagatcg gccccccatg tggaaagccc ggcgcgcagg
     7441 catgaacgcg cagcgcccat tcccattgag ccaagcccca caatgccgac atgaaaatca
     7501 gttcctgttg tcattatcac tccatgttaa tttacgtgat attatgtttt gttatgtgaa
     7561 tataggcgtt tttgtaaaca attgcggtga gttgtttcac aaaaaataac aaaatatgtt
     7621 attttttgtg aaggcaatcc tcatagaact tcacacgctg tgacgagaaa tcgcgtaaaa
     7681 tcgcgacagg actaaagaaa ggagcagacg ttgataccta ctgagcgtcg acaaatcatt
     7741 cttgatatgg tggcggagaa aggcatcgtc agtatcgctg aactgaccga gcgcatgcat
     7801 gtatcccaca tgactatccg ccgtgattta caaaaactgg agcagcaagg cgcggtaatc
     7861 caggtctctg gcggcgtgca atcatcgact cgcgtggcgc acgaaccctc gcatcagatc
     7921 aaaaccgaac tggcgacgcc gcagaaagcg gcgattggca aactggccgc cagcctggta
     7981 cagccagaaa gctgtatcta ccttgatgca ggtacgacca cgctggcgat cgccaggcag
     8041 ctggttacga tgaataaact tacggtggtg accaatgatt tcgttatcgc cgattacctg
     8101 atggacaata gcggttgcac aattattcac actggcgggg cggtatgccg ggaaaaccgg
     8161 tcgtgcgtcg gtgaagccgc ggcgacgctt ttgcgcgggc tgatgattga ccaggccttt
     8221 atttccgcct cttcctggag cgtgcgcggt atttcaacgc cggcagaaga taaagtcacg
     8281 gtgaaacggg ccgtcgccag cgccagccgc caaaaaattc tggtgtgcga cgcgaccaaa
     8341 tacggccagg tcgcgacgtg gctggcgtta tcgctggcgg aattcaacca aatcgtcacc
     8401 gatgacggcc tgccggaaag cgcaattcgg gcgctggcta aagtggatat ctcactgctg
     8461 atggccaaac aatagcgaag cggcgcaagc cgcttacgtc atcatcttgc gaaccagttg
     8521 cgtaaactgt tcgcgttctt cagcgctcag tcgccccaaa aactcatcgt caacgcgatc
     8581 ccccagtggt atcgcggcgg cgagcaacgt ttggccctga acggtgagat agacaaaacg
     8641 ccgacgttta tccagcggat cgttttctcg ctttaccagc ccacgatttt ccatccggct
     8701 taacatctcc gccagcgtcg ctttagtgct gaccgccgct tcggtcagat cgacctgttc
     8761 aatacccgga tgttcagcaa taacgcgcat caccgcatat tgaggtttgg tgagctccgg
     8821 tagttcatgc tgccagcgtg cggtatgttg ctgaaaaagt tggcgtaaca gatgaaacgc
     8881 ggtgtttcgt aactccatga gcgctccgga taaattaact ttttctatca taacgactta
     8941 tgcacggttt tttaatgacg aatgctttag ctaaacgtgc gcaggcatcg ggagcgatct
     9001 tgtcgcaaag gccgtgtggg cgtattttga tcaaaatgtt cgtatacgaa cgatatttga
     9061 ggtaagaaat gagattgatt gtggggatga ccggtgcgac cggcgcgccg cttggcgtcg
     9121 agctactcca ggcattgcgg gcgatacctg atgttgaaac gcatctggta atgtcaaagt
     9181 gggcgaaaac cactattgaa ctggagacgc cctacacgcc cgctgaggta gccgccctgg
     9241 cagattattg tcatagcccg gccgatcagg cggcgaccat ttcctccggc tcatttcgta
     9301 ccgacggcat gattattatc ccctgcagta tgaaaacact ggcgggggtt cgcgccggct
     9361 atgccgatgg gctggtggga cgcgctgccg atgtcgtgtt gaaagagggt cgcaagctgg
     9421 tgcttgtgcc gcgggaaatg ccgctcagca caattcatct ggaaaacatg cttgcgcttt
     9481 ctcgtatggg ggtggcgata gtgccgccca tgcccgcgtt ctacaacctg ccgcaaaccg
     9541 ttgacgatat tatccagcac atcgtggcgc gcgttctcga ccagtttggt ctggagcata
     9601 cgcgcgcgcg ccgctggcaa ggactgcgac aggcagcaaa tttttcacag gagaatggat
     9661 aatggcattt gatgatttgc gcagtttttt acatgcgctg gatcagcagg gacaactgct
     9721 gaaaatcagc gaggaagtga atgcggagcc ggatctcgcc gccgctgcca acgcaacggg
     9781 acgaatcggc gatggcgcgc ccgcgctgtg gtttgacaat attcgtggtt ttaccgacgc
     9841 ccgcgtggcg atgaatacca tcggttcctg gcagaaccat gccatctctc tgggtttgcc
     9901 gcctaacacg ccggttaaaa aacagatcga tgaatttatt cgccgctggg acaattttcc
     9961 ggtagcgccg gaacgacggg cgaatccggg ctgggcggaa aataccgtcg acggcgacgc
    10021 gatcaacctg tttgatatcc tgccgctgtt tcgtctgaac gacggcgacg gcggattcta
    10081 tctggataaa gcctgtgtgg tatcacgcga tccgctcgat cccgataact tcggcaagca
    10141 gaatgtcggc atctaccgta tggaagttaa aggcaagcgt aagctgggtc tgcaaccagt
    10201 gccgatgcat gatatcgcat tgcacctgca caaagccgaa gagcgcgggg aagatctgcc
    10261 gattgcgatc acgttgggta acgatccgat cattaccctg atgggcgcaa cgccgctgaa
    10321 atacgatcag tcagagtatg aaatggcagg cgcgctgcgt gaaagcccct atcctatcgc
    10381 caccgcgccg ctgaccggtt ttgatgtacc gtggggatct gaagtcattc ttgaaggggt
    10441 catcgaaagc cgtaaacgtg aaattgaagg gccgttcggc gaatttaccg gccactattc
    10501 cggcggtcgc aacatgaccg tggtgcgtat cgataaggtc tcttaccaca gcaaacccat
    10561 ttttgaatcg ctctatttgg ggatgccgtg gacggaaatc gactacctga tggggccggc
    10621 gacctgtgtg ccactgtatc aacagctgaa agccgaattt ccggaagtgc aggcggtaaa
    10681 cgctatgtac acccacggct tgctggccat catctcgacc aaaaaacgct acggcggctt
    10741 tgcccgtgcg gtgggcctgc gcgcgatgac gacgccgcac ggtctgggat atgtgaagat
    10801 ggtgatcatg gttgatgaag atgtcgatcc atttaatctg ccacaggtga tgtgggcgtt
    10861 gtcgtcgaaa gtgaatccgg caggcgatct ggtacagcta ccgaatatgt ccgtcctgga
    10921 actggacccg ggttcaagcc cggcggggat taccgacaaa ctgatcattg acgctaccac
    10981 gccggttgcg ccagataacc gtggtcacta tagccagccg gttgtggatt taccggaaac
    11041 taaagcctgg gctgaaaagc tgaccgccat gctggccaac cgtaaataag gagtaaccga
    11101 tgatttgtcc acgctgtgcc gatgcacata ttgaactcat ggcgacttcg ccggtaaaag
    11161 gagtctggac ggtatatcag tgtcagcatt gtctgtatac ctggcgcgat accgaaccgt
    11221 tacgccgtac cagccgcgaa cactatccac aagcgtttcg catgacgcaa aaagatattg
    11281 atgacgcgcc aatggtgccg agtatcccgc cgttgctggc agaagacaaa cggtaaaaaa
    11341 aaggccagtc tgtcgactgg cctttttttg acaagggtac ttactcgcgg aacagcgctt
    11401 cgatattcag cccctgcgtc tgcagaattt cgcgcagacg gcgcaggcct tcaacctgaa
    11461 tctgacgaac acgttcacgc gtaagaccga tttcacggcc tacatcttcc agtgtcgcag
    11521 cttcatatcc cagcagaccg aaacggcgcg ccagcacttc acgctgtttg gcgttcagtt
    11581 cgaacaacca tttgacgatg ctctgtttca tatcgtcatc ttgcgtggtg tcttccggac
    11641 cgttctcttt ttcatcggcc aggatgtcca gcaacgcttt ttcggaatca ccgcccagcg
    11701 gggtgtctac cgaggtaatg cgctcgttga gacgaagcat acggctgacg tcatcaaccg
    11761 gtttatccag ttgctctgca atttcttccg cactcggttc gtggtccagt ttatgcgaca
    11821 actcacgtgc ggtgcgcagg tatacgttca gctctttaac aatgtgaatc ggcaagcgaa
    11881 tcgtacgggt ttggttcata atcgcccgtt cgattgtctg gcgaatccac caggttgcgt
    11941 atgttgagaa gcggaacccg cgttccgggt caaacttctc gactgcacgg ataagcccca
    12001 ggttgccctc ttcaatcagg tccagcaacg ccagtccacg attgccataa cggcgggcaa
    12061 tttttaccac cagacgcagg ttactctcaa tcatgcgacg gcgagaagcg acatctccac
    12121 gcagtgcgcg acgcgcaaaa tagacttctt cttcggctgt taacagtggt gaatacccaa
    12181 tctcaccaag gtaaagctga gtcgcgtcca acacacgctg tgtggcccct tgcgataaca
    12241 gctcttcttc agccaggtcg ttatcactgg gttcctcttc actcaaggct ttttcgtcaa
    12301 aagcctctac tccgttctca tcaaattccg cgtcttcatt taaatcatga actttcagcg
    12361 tattctgact cataaggtgg ctcctacccg tgatcccttg acggaactag caagtcaaag
    12421 cctggttccg ccgctttatc gctgcggtaa ataacgcagc gggtttacgg atttcccctt
    12481 gtaacgaatt tcaaaatgca agcgtgtaga gctggtgccg gtgctaccca tagtagcgat
    12541 tttttgcccc gccttaactt cctgttgttc ccggaccagc atcgtatcat tatgggcgta
    12601 ggcactcagg taatcatcgt tatgtttgat gataataaga ttaccgtaac cacgcagtgc
    12661 gttaccggca tatacgacgc gcccatcagc ggttgcgacg atagcctgtc ccttactgcc
    12721 tgcaatgtcg atccctttat tgcccccttc ggaagcgcca aagttttcga tcactttgcc
    12781 atccgtcggc cagcgccatg cggaaatcgg cgcgctggtt gacgtactgc ttgcatttgg
    12841 ttcggtcgtg cttaccgttg gtgccgttac aggcgctgtg acaaccgtcc cagcaggctt
    12901 gttgtttggc aacattttgt tagcactttg ttcacctgag ccctcagaat acgtaattgt
    12961 tggttgagac gcaactgcaa cggtggaatt ttgtgcagac ctggtcacaa ctccttgctg
    13021 tgctgcatcc gcctgggtga tcgcatttcc gccagtaatt ggcgtaccgg atgcgttacc
    13081 aacttgcaaa gtttgcccta cattcaggct atacggggca gaaatactgt ttctctgggc
    13141 cagatcgcgg aaatcattcc cggtaatcca ggcgatgtaa aaaagcgtat cacccttttt
    13201 cacggtgtaa gtactgccgc ccgtatagct acctttcgga atattcccat actggcgatt
    13261 gtatacgatt cgcccatttt ccatctgcac gggttgttcc gtgaccggtt gagtttgcat
    13321 gggctgcgtt acaggacgct gaacgggttg aatttgcggc gcttgttgcg gcgtcgcgcc
    13381 catttttggc ggcggtgtga tcaacatccc ggaattggta tttgatgacg acccactgtc
    13441 cacagacgtg accggcgccg gagggtttga cgaactggta caacctgcca gccatagtga
    13501 aaccagtgat agtgccgcaa tgcgactaac ggtgaatttt gggcttcccg cgctcattta
    13561 tcccccagga aaaaatttgg ttaacaacca gtgacgtaag aaccgtgcaa cgcattaagt
    13621 gaacacggga aaatgtgttc acgatacgct taacccaccg ggaataacca ggaaaactcc
    13681 aggtattcgt ttcggcttca tcaggcgtaa tagtggctgt ttgcagggca aactaggcca
    13741 gctctccctt gactaacggg acgaagcgaa cggcctccac ggtatcgata ataaattcgc
    13801 cgccccggcg acgcacgcgt ttcaaaaact gctgctcatc gcccacaggc agaacaagaa
    13861 tgccgccttc atccaactgt gccatgagcg cggtaggaat ttccggcggc gcggccgtca
    13921 caatgatagc gtcaaacggc gcacgcgcct gccagccttg ccagccatcg ccatgacggg
    13981 tagaaacatt atgtaaatcg agctgcttca ggcggcggcg cgcctgccat tgcagcccct
    14041 taatccgctc aacggagcaa acgtgatgta ccagatgcgc tagaatcgcc gtctgatagc
    14101 cggaaccggt gccaatttcc aacaccctgg attgcggcgt cagttcgagc agttccgtca
    14161 ttcgcgccac catatagggc tgcgaaatcg tctgaccctg gcctatcggc aaagcgatat
    14221 tttcccaggc cttatgttca aacgcttcat caataaattt ctcgcgcggc actgcggcaa
    14281 gcgcattaag caccagctca tctctgatgc cctgcgcgcg caattgttca agaagagcct
    14341 gtacacgtcc acttaccatt gcgtgccaac tcccacgctg tctaaccagt ctgaaaccac
    14401 atcatgcgcg ctgtgcgcgg ttaaatccac atgcaacggc gtgacggaga cgtagccttc
    14461 atccaccgcc gcgaaatcgg tatccggccc ggcatcgtat ttatcacccg gcgggccaat
    14521 ccagtacaat gtattaccgc gtggatcttc ctgcgggatc actttatccg ctggatggcg
    14581 gctaccgcag cgagtcacgc ggatgccttt aacctgcgct aacggtagat ccgggacatt
    14641 cacgttgaga atacgcccgg tacgcaacgg ctcccggctt aaccctcgca aaagcgcgca
    14701 agtcacggct gcagccgtat cataatgctg atagccgtta agggagaccg ctaatgccgg
    14761 aaagccgaga tgacgacctt ccatcgccgc ggcgacagta ccggaataga tcacatcatc
    14821 gcccagattc ggacccgcgt taataccgga aacgacaata tccggacgcg gacgcattaa
    14881 ggcattaacg cccagataga cgcaatcggt cggcgtcccc atctgtacag cgatatcgcc
    14941 attatcaaag gtaaaagtac gaagcgaaga ttccagcgtg agggaattag acgcgccgct
    15001 gcggttacga tccggggcta cgacctgtac atcagcaaac tcacgcagcg ctttcgccag
    15061 cgtttgtata ccgggcgcgt gaaccccgtc atcgttactc agcaatatgc gcataatcac
    15121 ccattgtgtt gatcagttcc cttactacgc tggtggcaaa actgcctgcg ggcagccaga
    15181 aacgtaactc gacggtaacg tcatcccacc agttccagct taattgttgc ggataaagca
    15241 gcatcgctct gcgcgacgcc tctacttttt cgcgcagcaa cagcgattgc aacaccgttt
    15301 cctgggcaat ggcatcttgc tcaaacgcca gcgccgcacg ctgtgttccc cactctccgc
    15361 tgcccggcaa cgacgctgta atcatcagct ctttttcgtc tacccggcgc tgcaattcag
    15421 gcagttcttc agatgtcgcg acgaaccagc ttccacgccc cgctaattgt agcgcatcgc
    15481 cgtcaacaac ttgattaaag tctggtttct tcagccgctg gtgaacaatt tgattaaaca
    15541 acgcgctacg cgccgccgac aaccaaaaac tgcgtttatt gcgatcgcgc accggcgcgt
    15601 tactttgcgc ccagcgcagc gcgccctgca agttgctgcc gccaatgccg aatcgttgtg
    15661 cgccaaaata gttcggcacg ccgccatcgc gaatcgcctg caatcgtgtt tcgacatcgc
    15721 ggcgatcgct tatttcacgc aataccagcg taaaggcatt gcctttcagc gcgcctaaac
    15781 gcagcttacg cttgtgacgc gcgtattcca gtactttaca accttccagc tgaaaggcgc
    15841 tgaaatcggg catctctttc cccggcacgc gcgcgcacag ccactgctcg gtaacggcgt
    15901 gtttatcttt ttgcccggca aagctcactt cgcgagcgtg aattttcagg aatttcgcca
    15961 gcacgtcagc gacaaaacgg gtattgcaac cgtttttcaa aatacgcagc agaatgtgct
    16021 cgccttcacc atccggcgta aagcctaaat cttcaaccac cacaaaatct tccggattcg
    16081 ctttcagcaa tccgctacct tgtggttttc cgtgcagcca ggtgagattg tcaaactctg
    16141 tcatttcgcc gccttcatca gcaacgccac cgcttcgcag gcaatgcctt ctccgcgtcc
    16201 ggtaaatccg agcttttccg tcgtcgtcgc cttcacgtta acatcatcca tatggcagcc
    16261 gagatcttcg gcgataaaga cgcgcatttg cggaatatgc ggcagcattt tcggcgcctg
    16321 cgcaataatg gtgacatcca cgttgccgag ggtgtatccc ttggcctgaa tacgacgcca
    16381 ggcttcacgc agtagttcgc ggctatccgc tcccttaaat gccggatcgg tatccgggaa
    16441 gagcttgccg atatcgccaa gcgccgccgc gcccagcagc gcatcggtca gcgcatgtaa
    16501 cgccacatcg ccatcggaat gcgccaatag ccctttttca taagggatac gcacgccgcc
    16561 aataataatc ggcccttctc cgccaaacgc gtgtacgtca aaaccgtgtc caattcgcat
    16621 tatgctttct cctggtggat ggttcgggtc agataaaatt ccgccagcgc cagatcttcc
    16681 ggacgggtga ccttgatgtt atccgcgcga ccttctacca gcgccggatg aaaaccacaa
    16741 tactccagcg ctgacgcctc gtcggtgatg gtcgcgcctt cattcagcgc acgcgtcaga
    16801 caatcgtgca agagttcgcg ggggaaaaac tgcggggtga gcgcgtgcca taaatcggcg
    16861 cgctctacgg tatgggcaat agcgtttttc cccggttcgc cgcgtttcat ggtgtcgcgc
    16921 accggactgg cgagaatacc gccgacccgg ctgttttcgc tgatggccag taaccgcgca
    16981 aggtcatcct gatgcaaaca gggtcttgcc gcgtcgtgca ccagcaccca ctgcgccttt
    17041 gcaacggcct gtaacccggc caaaacggaa tcagcgcgtt cgttgccgcc atccacaacg
    17101 gtgatttgcg gatgattcgc cagcggaagt tgggcaaagc gatgatcgcc agggctgata
    17161 gcaataacaa cgcgtgtcac ccgaggatgc gccagcagcg catgaactga gtgctccaga
    17221 atggttttat taccgattga gagatactgc ttaggacatt ctgtttgcat tcggcggcca
    17281 aatccggccg ccggcaccac ggcgcaaacg tccaataaag tggctgccat gttaaatccc
    17341 tggatggttt atcgatgagt ttgccccgcc gttgccgcgc gttttgaggc gtcaggcacc
    17401 agacgataga aggtttcgcc cggtttggtc atgctaagtt cgttgcgcgc gcgctcctca
    17461 atcgcttcct ggccgccatt gagatcgtca atttcggcaa aaagctgatc gttacgcgct
    17521 ttaagtttgg cgtttgtcgc ctgctgcgcg accacatcat cgttgacgcg gctatagtca
    17581 tgtatgccgt tcttaccgaa ccacagcgag tactgtagcc agaccagtaa agccagcaac
    17641 agcagcgtta gtttacccat cctgccccct gaaaaacggc atcatcatcc cataacgtcc
    17701 tctgtgactc cacattcagg acgggattgc cgcgacaacg ccggcaaatg taccacattt
    17761 gccggatgtt acgtataccc gagtaaggag aacataatct cattgttggt tacggtttga
    17821 attatgaccg gaggcgcagt gataacccgt ctaccctaat agccatatga ataacgcgcc
    17881 gaacagcgcg cctacggcca gtagagtaaa catgatgcta aaaagtattt tgccctttac
    17941 caacagatgc aacgcaatgc cgataatcac cgataccggc attaacgcga ggaaaaaggg
    18001 ccaagtatag aggaaaaaaa acagcgtgtt agggccataa agcagaaaag ggatccccaa
    18061 cgccagcagc catgacacaa agccgaccac cgcccccgga aatgcactgg tggcgtcatc
    18121 gtcgaccatg aaggcgtctg accttgtgaa agtaatgtta tggctattac gcatattaaa
    18181 tcctgtaacc ttgaccatac cgggcataca agcccggtgg tgtctcagga tctgataata
    18241 tcgcgccgtc tcagcaggtc taataattgg gaaaccaaat ttgttactaa ttgttcacca
    18301 ttaagatgaa cctggggcga gtcaggcgct tcgtaaatgg cgtcgatacc ggtaaagtta
    18361 cgcaactcgc ccgcgcgcgc ttttttatac aatcctttag gatcgcgctg ttcacagata
    18421 gccagcggcg tattgacata aatctcgata aaacgatcgt ggccgacgcg ctcttttacc
    18481 agttgccgct cggcgcggtg cggagaaata aatgccgtca aaacaatcag gccagcgtcc
    18541 gccatcagac tggccacttc gcctacccgc cgaatatttt cctggcgatc ggcatcgcta
    18601 aagcctaaat cacggcacaa accgtggcgc acattatcgc catccaacag gtaggtactg
    18661 acgccacgct gatgtaacgc ctcttccagc gcgccggcca ccgttgattt tcccgaaccg
    18721 gagagtccgg taaaccacag caccacgcca cggtggccgt ggagctgttc acgagcggcg
    18781 acagtaacgg gatgagagtg ccagaccacg ttctcatcat gcagcgccat gtttatctcc
    18841 cagcaaatct cgggcgtccc agtgcggaaa atgacggcgt accagcgcat tcagctccag
    18901 ctcaaacgca ctgtattcca cgggcggcgt cgctccgcgt tcatccagtt cccgcaccat
    18961 gccagcaccc acggtaacgt tagaaagtcg gtcgataaaa atcagcccgc ccgtcaccgg
    19021 attttgctga taaatatcca gcgcgagcgg ctcatcgaat gtcatctcta ccagaccaat
    19081 accgtttaac ggcaggctct cgacgtctcg ttgagtcaga ttgttgatat caatctgata
    19141 gcaaatagcc tcgatacgcg cgcgggtttt cttacccgca agtttaacgt cgtagctttg
    19201 gcccggcgcc agcggctgtt ccgccatcca taccacatcg atcgcggcgt gccgcgcagg
    19261 tgccagcgtc tcgtttgccg ccagcagcag atcgccgcgg ctaatatcaa tgtcgtcgtt
    19321 gagtaccagg gtaatggctt cgcccgcaca gacttcttct ttgtcgccat caaaagtgac
    19381 gatacgcgcc acgctggatt ccacgccgga cggcagcact ttaatgcgct ctccgacttt
    19441 gacgctacca gacgccagag tgccggcata cccccgaaaa tcagggttcg ggcgattgac
    19501 gtattgtact ggaaagcgca tcggctgacg gtctaccgca cgctgtatgt ctaccgtttc
    19561 caggacttcc aacagcgtcg ggccgctgta ccagcgcata ttggcgctct gcgcggcgac
    19621 attatcccct tccaacgccg aaagcgggac aaagcgaatg tccagatcgc ccggcaactg
    19681 ttcagcaaag gtcaggtaat cttcgcgaat acgggcgaag gtctcttcgc ggtagtcaac
    19741 gagatccatt ttgttgattg ccaccaccag gtgtttgatc cccaacagag tggagataaa
    19801 gctatggcga cgcgtctgat ccagcacgcc tttacgcgcg tcgatcagta ggatcgccag
    19861 atcgcaggtg gacgctccgg tcgccatatt acgggtatat tgttcatggc ccggcgtgtc
    19921 ggcgataata aattttcgtt tttccgtgga gaaatagcgg tacgcgacgt caatagtaat
    19981 gccctgctca cgctcggcct gcagcccatc taccagcagc gccagatcga gtttttctcc
    20041 ctgcgtgcca tgacgtttac tgtcattatg cagagaagag agctgatctt cataaatttg
    20101 cagggtatcg tgcagcaaac gacctatcag cgtactttta ccgtcatcaa cgctgccaca
    20161 ggttaaaaaa cgcagcaggc ttttgtgttg ttgggcaatc atccaggctt cgacgccgcc
    20221 ttcactggcg atttgttgtg caagtatggt gttcatggcg gctccttaga aatacccctg
    20281 acgtttttta agctccatcg accccgcctg atcgcggtca atcatcctcc cctggcgctc
    20341 gctggtggta gaaaccagca tctcttcgat aatttccggc agcgtttgcg cgtgggattc
    20401 caccgccccg gtgagcggcc aacagccaag tgtacggaag cgcaccatcc tttttttgat
    20461 gacttcgcca ggttggaggt cgatacgatc gtcatccacc atcatcaaca tgccatcacg
    20521 ttccagaacc gggcgttcag cagccaaata cagcggcacg atgtcgatgt tttccagcca
    20581 gatgtattgc cagatatcct gctctgtcca gttggagagc gggaagacgc gtatactttc
    20641 gcctttatta atctgaccgt tatagttacg ccacaactct ggccgctgat ttttcgggtc
    20701 ccagcgatgg aaacggtcac gaaaggagta aatacgttct ttcgcgcggg atttttcctc
    20761 atcgcgccgt gcgccgccga acgcggcatc aaaaccgtac ttattcagcg cctgctttaa
    20821 cccttcggtt ttcataatgt cagtgtgttt agcgctaccg tgaacgaacg gattgatgcc
    20881 catcgccacg ccttctggat ttttatgtac cagcaattcg cagccgtatg cgttggcggt
    20941 acgatcgcga aaggcgtaca tctcacggaa tttccaaccg gtatcaacgt gcaatagcgg
    21001 gaacggtaac gtacccggat aaaacgcctt acgcgccaga tgcagcatga cgctggagtc
    21061 tttaccaatg gagtacagca tgaccggatt agcgaattcc gctgctactt cacggataat
    21121 gtggatactt tccgcctcca gttgccgcag gtgggtgagt cgtttttgat ccataaccgt
    21181 tcctttgcaa taccgttttt tgctaaacat ttcgattaca cgactatagg gagcgcggga
    21241 gagtgaatga aatgacgaat tggaatgagt agttcctcaa aggaataacg cggcccaaaa
    21301 accaatatca aaaaatgctt aacgtaccgg attgccagca tttaggagca aatgaaattg
    21361 tattaacacg atcgcggttt catactagcc ccgtaaaatt ttgttctgta tttaaggact
    21421 cattatgttt tccgcaacgc gccgctttgc cgtcattctg gcgctcggcg taggctttat
    21481 ccttcctgca caagcagcat caccagggcc tggtgaaata gcgaatactc aggcacgaca
    21541 tatcgccacc ttttttcccg ggagaatgac tggctccccc gccgagatgt tgtctgccga
    21601 ttatttacgc caacaattta cccagatggg ataccaaagc gatattcgaa cgtttaatag
    21661 ccgatttatt tataccacga aggataatcg caaaaactgg cataacgtga cgggcagtac
    21721 ggtcatcgcc gcccatgaag ggcgcgtgcc gcagcagatc atcattatgg cgcatctgga
    21781 tacctacgct ccgcagagcg atgctgatgt cgatgccaat ctgggcggtt taacgttaca
    21841 gggaatggat gataatgccg cgggattagg cgttatgctg gaactggcgg cgcgtctgaa
    21901 agatataccg acccattatg ggattcgttt tatcgccacc agcggggaag aagagggaaa
    21961 gctaggcgcg gaaaatttac tcaaacgaat gagtgacgct gagaagaaaa atacgctgct
    22021 ggtgattaat ctcaataacc tgattgttgg ggacaagctc tattttaata gcgggaaaaa
    22081 tacgccggaa gcggtgcgta cactgacccg cgatcgggca ttagcgattg cgcgccgtta
    22141 tggcatcgcc gccaacacca atccgggacg caatccatcc taccccaaag gaacgggttg
    22201 ctgtaatgat gcggaggttt tcgataaagc gggaatatcg gtgctttctg ttgaggcgac
    22261 gaactggaat ctgggtaaaa aagacggata ccagcaacgt gtgaaaaatg catccttccc
    22321 gaacggcaat agctggcacg acgtacggct tgataatcaa cagcatatag acaaggcgct
    22381 gccagggcgg attgagcgcc gtagccgcga tgtagtgcgg ataatgctgc cgttggtaaa
    22441 agagctggcg aaggcggaaa aaacgtcctg atatgctggt gaaacgtgtt tatccccgct
    22501 ggcgcgggga acacggacag caacccgtgt cggatatcag acagatcggt ttatccccgc
    22561 tggcgcgggg aacacacgcg aatcgccaat cgccgccgcg tgaattgcgg tttatccccg
    22621 ctggcgcggg gaacacccac gatgtatgcc gaccgtgatt tttaccgccg gtttatcccc
    22681 gctggcgcgg ggaacacaga tacgccttta cgtcgccctc tttggcgcgc ggtttatccc
    22741 cgctggcgcg gggaacacat taaaaaagat taatgttggt tatagtttta cggtttatcc
    22801 ccgctggtgc ggggaacact aaaacaccgg ttgcgcaacc tccgcgggga tcggtttatc
    22861 cccgctggcg cggggaacac tctaaatcta cccaattgaa tttaaatact tttttagcgc
    22921 acaaaaaacc caccaacttt tcctaatttt taaagatctc taacttattg attttcaaca
    22981 ggtagaaacg acaccaatcg cagtccatca agatctaccg gaatacgtcg atttacacca
    23041 aaagtctgaa actcaaaacc tgattctgta tttgtcgccc acgccataac aacatttccc
    23101 tcatctgcca gaacggaaac ctgttgccat atcatctcgc ggatctttgc ggaaacatca
    23161 ccaacataca caccagctcg aatttccagt aaccagacgg ccagcctccc ccgcagacga
    23221 ggaggaacat tttcggtaac gacaaccagc atactcatcg ttaggtactc cgatgaccgg
    23281 aatctcccaa cgcaacagga agagggatcg ctatggggtg tgaatcttca ggaggtaacg
    23341 gcggttgaat ttcccctgcc gcgagaacat cttcaataag aggaatcaat ttcgccaatg
    23401 tttttccact gcggaagata tcccggcagg caatacggac atcacgatcg ggctcggcag
    23461 gattacgtcg cgcaatttca aatgctttcg gtacaacgat ctcaaattta atgatatcgg
    23521 caatatcata gacaaaagaa agcggcttgc cggtgtgcac aaatccaatc gcgggcgcat
    23581 atccggcagc cagtattgcc gcctccgtta cgccatagag gcaggaggtt gccgagctga
    23641 tacactgatt aatgacatcg cctttctccc agtctttcgg atcgtagcga cgtccctgcc
    23701 atttcacgcc atactgctta gcaagtagtg cataggttgc ccgcacacgg ctcccctcaa
    23761 taccacgcaa ttgatctaca gaacgacggc tcggcgcggg ttcgccaaaa cgtaattcaa
    23821 acattttacg cacgaccttc agccgcaaat cttcatccag tgcaagtttc gcctgataaa
    23881 gcaatttgtc ggaacgggca ccaccaggct gccccgaagc gtaaacgcgt acgcccgctt
    23941 ccccccccca caccagtaac gtacccaccg ttgccgcaag tcgcacggcg gcatgggaaa
    24001 cccgcgtccc cggttccagc atgatgcagg ccaccgatcc aacaggaata tgggtacgta
    24061 cacccgtttt atcgataagc acaaacgcac cgtcgatcac atcaatttgt ccgtactgga
    24121 gaaatatcat cgaaacacgg tctttcaacg ggatgggatt cagcggcagc cagctcatca
    24181 gcgtttcctt tttaccatca gcattccgca gcccagcgct ttacttttac ctaatccgga
    24241 aaataaagcc tgtttaaaca gtgctgcatc ggtgatacag agcgcaccgc taaaatcaac
    24301 gctactgaaa gtgattgggg tttcctggtc tttacggaca aaacgatgtt gctgatacgc
    24361 ttgcacgcat ccacaatgcg cctgcaattc actgtactcg tcaccagccc acatagcgaa
    24421 atcatcaggt tccggtgcaa tcaaccggaa accatgctgc tgcccttgtt gttccagcca
    24481 cgcctgcgcg gcctgctgtt gaagctccca ccaccgttct ttctccacac cattcgcctt
    24541 cgcctgatgt ttcgcgttca tcatcacgtc actgcgctta ccgttacggg ttatcaccgg
    24601 gttagctcgt agttgaaaat caagctcaag accatttgtc agttgcggat taaatagttt
    24661 ggtttcaata agaaacaggg agtgctgcaa taacggcggt attgccgaga gcataaaaaa
    24721 gccgccatgc gcctcttcgc gaaacagaaa ctgacgcaat tcctgttccg gaaagagctg
    24781 ccataaccac tggtggctgg cataaggcct ggctgaattc cactttgcca acatctccgg
    24841 tcgcaaatta ttaaaccgga gttgaatacg agaaagatac attatgttct ctcctgcaac
    24901 ggcccattga agcgggtgta gccgccaaac tgccagcgtt ggcggctaac tggctggtta
    24961 ttgctatgct gcttttgttg ccagaccaga ctctcctcat caggatcatc ccaataacaa
    25021 ataccctcac gcagggtaaa tccacttaat tccgctgcgg aaatctcctc cacagcatga
    25081 gtgaatacct cttttaaggt gccggtcatt aaacgcgccg ctaacggtaa cgccagcggg
    25141 caggattttc tccccagata gagcggaaaa tgcggtgtca gcagcgcctc tcgcaattcg
    25201 ctaagcgaat atggtgcatc aggcgtggcg cttattgcca catgccagta gccatcgcag
    25261 cgatactctc gctgcgagat aagcgttccc acttcatccg acgcgagagt cagttcatcc
    25321 cggcgcgtgt aataacgata ctttttgttt tctcgcggcg cgctaaccgt gtgataatcc
    25381 cgcaaccagc gatcttgtga agccaacgcg tgcaccgcca gatgatagtg ccggttaaag
    25441 ttattcagcc gcgcttcttc gtcgcgacga attcctaacg ctgcggcaag cagacccaat
    25501 agcgcagagc gcgtgggaac cgtagctgag tggcgaatct cgccagacgc ttcctccccc
    25561 cacgacgcca gcggcgcata aagctgaaaa accagatatt ccttcattat tcatccttac
    25621 tggctaacaa aggccagtaa ttccgccaga gatcccgtac cttcctgaac gttcaactcg
    25681 cgataatcgt ctgcacagtt tccatatacg ctatcgaagc tggcgcgctg ctgttttaaa
    25741 cgggttattg ccgcaggaat ttgatcggta tcgcgtaccg gctggaaaaa tgccgccgcc
    25801 agagaacgcg gttgtttttg cccgacttcg gccaacgcat aggtggcata ggcacgagaa
    25861 gcgaagctgt tttgtttacc ggttggcgag acggttaacg ctgtttcagt gagtgccgcg
    25921 atagtacgct tcgccagttc ttcgttacca cccaggtttt ccaccagcag atcgcggctg
    25981 atacagacat aggtatagaa aagcgccgag gcaaaaccct gctcgcccat atgcccggaa
    26041 cctgcgtctt cctctttatt attcagatcg tcaacggcgg tgaaaaaatc agactcaacg
    26101 gtcacggcac ttacgcccaa cgcatgggat acctgacaag cagcctcgac gttgaactca
    26161 ggcgatgacg ccagcatacg gtcaaacagc gccatatcta cgctacgctg ttctttgcgc
    26221 agaagcttca cttcttcatc gttaggttcg cgtttgtcgg caattagcgt atcaaccagt
    26281 tgtttaatca aactaatttc atggttactg acgtgaacga tctgctcaat ttcgagattt
    26341 ttttccggtt tcgcatcttt atcactttta agcttgccaa attgcttagc gattaactca
    26401 gacgaactct tagcaatttt ttcttcaatt ccggcatctt tcatcggacg ataaacataa
    26461 tccacgccaa ttcgacgagt acgcttaccc ataaagccat ccattgccgc ttcaaaagtt
    26521 tccgacaccc gccaggcacg cttcagactt tgcgacgata cgcgtaaacg ctcaactcct
    26581 cccataaacg cggtcttcgg tctgccagac tcatcacgat tcaggttagc gggcgcataa
    26641 gcagtcaata aatgcagttg aataaaagtt gtcattatca aatccttcta aaaatgatta
    26701 tttgccacgc gacgtggaaa gatattcgtt cgcccaacgg atgcgacttc gttcaaaggg
    26761 gttacggaat tccggctgat ggttttcgcg tcgttgccac tcttccatcc acaggaaaat
    26821 gccatcggca agtgaaagaa cattcacccc ctccgtaccg cgaatcttca ctgcctgaat
    26881 caacaactgg caaaatgttt ccgggtcgga cgctttttgc aaacgttcaa aacgcagacc
    26941 agaaacgcac gacgtggaac ctttaagctt ttcccctaac tgcgcagcga aactaatatt
    27001 ctccttatga ctcttaatat gcacagcgac gctgacaaac agagccagag ccatctcatc
    27061 aagaggttgc agtcgcatat gtttaagcag agcctggcgg agagcgtcat gtccttcaca
    27121 tatcattacg ccatatggcg gcgccattct tttcaactca gcccgccagg cgcgaccgtt
    27181 gactcgttta ccatccttgc gctcataacg ctcagacagc gtagcaaacc agtcaagtag
    27241 tgccttctgc gcatcggggt ggagaattct gcataacact gctgtattgc tattcagcat
    27301 atttggcttc cttctgttat tcgaccagcg ccaacacatc cttgcgcgct ttatgtttac
    27361 gatagctgct ggctaaatcc tgtcgggccg tcagctggcg ctgcaggata tcgtccgggc
    27421 agtcggggtt ggtcagggca tcacggtcaa aaacgtgaaa tagatagtgt gctaattccg
    27481 cctcccactg acttactgcg tgacgagtct gtgtatcctg ccgaagcgga tcgacagcca
    27541 gcgcctcttg caacgtccga aaagcgggtt cggtttcctg ccagaaggcg atatccacca
    27601 tactaaaatc cattttggct tctttcggac aatcgaattt ggcgctcttt aacgcgttcc
    27661 gtaacagcga cagcgactca ctagccagca ccagcacaat gttaagcgca gcgagaaatt
    27721 gctcttcgtg cgaaacgcta atgagcggaa ttcggtgctg ataccagcag cggaccttgg
    27781 ccttattcat atcccaggca aagcaccaca ggctcatttt gttccgctga ccagcggcac
    27841 gaacgacctt tgcaggctgc attttgttga acttatcctc acgattgagc atcagcccca
    27901 accagtcttt ataacttaac ccgcccggct gccctttaaa cgccagccag ggtgcggatg
    27961 gatctttcaa tgcctgccga tatggggaga agggatgtag ccaactgtcg tactgaacgc
    28021 cataattttt actacgcatt tgcagtagca gtgattcgtg atgctccccg cacaaatcgc
    28081 agatacctgc cacagtgtgg gtgaaatcca gttctatgcg ccgcggcatc ccccagtagg
    28141 cttgcaaggg gtgcgcatta tccggtgtga ccacattccc cgctttttcg ctggttttcg
    28201 tcggcgcaag ccagggaaaa atgagtggat gctgtgtaac attcggcggc tcttcctgcg
    28261 gcaaaacgtt aagccaaagt tttttccata gtggatattt atcttcttcc tgcggtacca
    28321 ccagcgtagt cagcggacca ccgccgcgca tccctacccg gtaacccgcc ccgccggcag
    28381 gtgaattggt ttgaatcgca aatagcgcta tcgccgcgca gtgaggacat atttgttcta
    28441 cgttgccacg ttttacaaaa tgatctttat tgagcttgag cgcattcccg cccggcgcat
    28501 ccaccagcag cccggcaata gaaccatatt cactatcgag aggatcaaaa ctttgcagga
    28561 aggaaggttt ttgctcgccg aactgtagag ccagagaaat cgtatttaac gccttctccc
    28621 attgttcgaa ttcgatactt tcatgccaga tatctgccca ttcttcttta tcttccggcg
    28681 cgacggtaca ttgtaaaata ccaatcagca tttgccatgc cgccccctga aagtcagccc
    28741 gaggataggc aagatcctga atgcggttat ccagaagatc gcgtaatgat attttctttt
    28801 tatcgccgtt tgagaatatg acgggaagcc atttctcttt ggttaaatcc atacctttac
    28861 tcctgcaggg ctatttatta agccaatttg gaatattacc tacctatagg tagattccgt
    28921 cctgaggtat ctcttaaata ctgtcatcgg agttatacta cattttctcg aagacgaaaa
    28981 tataaataaa aagtagatac agtcttaaat c
//
LOCUS       DAJVKX010000050        27988 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000050 DAJVKX010000000
VERSION     DAJVKX010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 27988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27988
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.050"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..787)
                     /locus_tag="OPY25_002224"
     CDS             complement(<1..787)
                     /locus_tag="OPY25_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0927833.1"
                     /translation="MKNNIRFDLSDYLIHFFRDVDLETGSHIYLPEHCGFNNQHHACS
                     IDAKYLLRLSLRSHKIFSSWSYRNGQRTVYGDSPVVCFTDMPIAAYLETGVRRLERNE
                     NIGLYAIVLPKEQMFNYGARPVIYGLDQHNNARCSQGRYGERILDETALPLIEQYRYV
                     TYVPGKIDWTHEREWRWPYRGDIKKFLNHIKEYGIPENIESTPGFDFRSSEISGAGII
                     VPFAEDIPTVAHDILTLIDRGVIGRNTFKFIIAVESLQSWTQLS"
     gene            1282..2400
                     /locus_tag="OPY25_002225"
                     /pseudo
     CDS             1282..2400
                     /locus_tag="OPY25_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460742.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
     gene            2397..4190
                     /gene="hyaB"
                     /locus_tag="OPY25_002226"
     CDS             2397..4190
                     /gene="hyaB"
                     /locus_tag="OPY25_002226"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HCS0927834.1"
                     /translation="MSNQYQTQGYTVNDAGRRLIVDPITRIEGHMRCEVNIDEQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIQVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLNALKADPRATSQLAQSLSAWPMSSP
                     GYFFDVQNRLKKFVDGGQLGIFRNGYWGHPQYKLSPEANLMGFAHYLEALDFQREIVK
                     IHTIFGGKNPHPNWIVGGMPCAINLDQSGAVGAINMERLNLVQSIITRTADFINNVMV
                     PDALAIGQFNKAWSQIGTGLSDKCVLSYGAFPDIANDFSQQSLLMPGGAVVNGDFKNV
                     MPVDLADPQQIQEFVDHAWYRYPDDRLGRHPFDGITDPWYNPGDVKGSDTHIQQLNEQ
                     ERYSWIKAPRWRGHAMEVGPLARTLIAYHKGDAATIESVDRMMSALKLPLSGIQSTLG
                     RILCRAHEAQWAVGKLQYFFDRLMTNLKNGDLATANTEKWEPASWPQHCRGIGFTEAP
                     RGALGHWASIRDQKIELYQCVVPTTWNASPRDPKKQIGAYEAALMGTQMAIPDQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELIAVQVR"
     gene            4209..4940
                     /gene="hyaC"
                     /locus_tag="OPY25_002227"
     CDS             4209..4940
                     /gene="hyaC"
                     /locus_tag="OPY25_002227"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HCS0927835.1"
                     /translation="MTGKLSPRVGEARDTAVSHYVFEAPVRLWHWLTVACMLVLMVTG
                     YFIGRPLPSVSGEATYLFYMGYIRLIHFAAAMIFIVLLLGRIYWACVGNRYSRELFIV
                     PVWRRSWWQGAFSVVRWYLFLEKKPGSDIGHNPIAQAAMFGYFLLSVFMILTGFALFG
                     EHSQYAIFAPFRYVVEFFYWTGGNSIDIHSWHRLGMWLIAAFIVGHVYLAIREDIMSD
                     DTVISTMINGYRSHKFPKPHDKEPS"
     gene            4937..5533
                     /locus_tag="OPY25_002228"
     CDS             4937..5533
                     /locus_tag="OPY25_002228"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HCS0927836.1"
                     /translation="MNAQRVVVMGLGNLLWADEGFGIRVAERLYARYHWPEEVEIVDG
                     GTQGLNLLGYVEQASHLLLLDAIDYGLAPGSLRTYAGEKIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPCHIALVGLQPALLDDYGGSLSEIARSQLPAAEQAALAQLAAWGIVP
                     QANEVARCLNYKCLSMENYEGVRIRQYQTRLEGKRSGE"
     gene            5523..5927
                     /gene="hyaE"
                     /locus_tag="OPY25_002229"
     CDS             5523..5927
                     /gene="hyaE"
                     /locus_tag="OPY25_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HCS0927837.1"
                     /translation="MANDTPFSALWQRLLTRGWQPVEASTVDDWIKRIGDGVILLSSD
                     PRRTPEVSDNPVMIAELLREFPQFDWQVTVADLEQSEAIGDRFNVRRFPATLVFTDGE
                     LRGALSGIHPWAELLTLMRSMVDTPAAQETAQ"
     gene            5924..6772
                     /locus_tag="OPY25_002230"
     CDS             5924..6772
                     /locus_tag="OPY25_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HCS0927838.1"
                     /translation="MSNAFFHLLGPGTQPDDASFSMNPLPLTCQVNGDPSMAALERCA
                     HSPAVMALLTDLRGQLARRIPEVGDVLGWELSPLNADDLSFLNTLLGEGEVSVRIQHP
                     DGSESEIQETIFCGLWRVRHLHNRRLLTDRLEAGSAPLTLWQAATADTLPDDSLLPPP
                     VAGLMNGLPLAHELLAHVRDPALQPHSINLTQLPLSEADRLFLARLCGHGNIQIRISG
                     YGESQINATALRHLWHVRCLDALKGPLLDSYEICPLPELVLAAPEDLADSRQRLDEVC
                     RWLETR"
     gene            6847..8391
                     /gene="appC"
                     /locus_tag="OPY25_002231"
     CDS             6847..8391
                     /gene="appC"
                     /locus_tag="OPY25_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HCS0927839.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAVMETIYVVTG
                     KTVYRDMTRFWGKLFGINFALGVAIGLTMEFQFGTNWSLYSNYVGDIFGAPLAMEALL
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNISALWILNANGWMQYPTGAHFN
                     IDTLRMEMSSFSDLVFNPVSQVKFVHTVMSGYVTGAMFIMSISALYLLRGREREVALR
                     SFAIGSVFGTLAILGTLQLGDSSAYEVAQIQPVKLAAMEGEWQTEPAPAPFHLIAWPQ
                     QEQERNAFAVKIPALLGILATHSLDTPVPGLKNLMDDALPRLKRGREAWLLMQEIAQG
                     NRSPQVLNAFHAVEGDLGYGILLAKYAPDMNHVTPEQYRAAQRGAIPQVAPVFWSFRI
                     MVGCGSLLLVVMLIALIQTLRMRIDQHRWVLRMTLWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTWYAHSALTPGQLAFSMGLILGLYTLFLIAEVYLMQKYARLGPSAMQHQQ
                     QAQQQG"
     gene            8403..9539
                     /gene="appB"
                     /locus_tag="OPY25_002232"
     CDS             8403..9539
                     /gene="appB"
                     /locus_tag="OPY25_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HCS0927840.1"
                     /translation="MLDYETLRFIWWLLIGVILVAFMVTDGFDMGVGCLLPLIARNDD
                     ERRVLINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCALFLRPL
                     AFDYRGKIANARWRALWDTGLVIGSLVPPVVFGIAFGNLFLGVPFAFTPQLHVDYFGT
                     FWQLLSPFALLCGLLSLSLVIMQGGVWLQLKTEGVIRQRALSATRHSALLIVICFLLA
                     GYWLWAGVDGFVLLTQDANGPSNPLLKGVAILPGAWMNHFIRSPLLLIIPLLGMILPI
                     LAFYACLRGQTIRGFLFASLTQACVIFTAGITLFPFVMPSSVSPLSSLTVWDSTSSQM
                     TLEIMLVIVLIFLPIVLLYTLWSYYKMLGRINLETLRRNDHELY"
     gene            9552..9641
                     /gene="cbdX"
                     /locus_tag="OPY25_002233"
     CDS             9552..9641
                     /gene="cbdX"
                     /locus_tag="OPY25_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HCS0927841.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLESRQQ"
     gene            10037..11311
                     /locus_tag="OPY25_002234"
                     /pseudo
     CDS             10037..11311
                     /locus_tag="OPY25_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
     gene            11525..13237
                     /locus_tag="OPY25_002235"
                     /pseudo
     CDS             11525..13237
                     /locus_tag="OPY25_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460752.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
     gene            complement(13300..13554)
                     /locus_tag="OPY25_002236"
     CDS             complement(13300..13554)
                     /locus_tag="OPY25_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCS0927842.1"
                     /translation="MGIIAWIVFGLIAGVIAKLLMPGRDGGGFILTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAIVVLVIFRLLRRG"
     gene            13723..14457
                     /gene="ycgR"
                     /locus_tag="OPY25_002237"
     CDS             13723..14457
                     /gene="ycgR"
                     /locus_tag="OPY25_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein YcgR"
                     /protein_id="HCS0927843.1"
                     /translation="MSGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKIL
                     AVAPEKLIVDYGSQEYKNSAVLRAGQVAIIAETQGAKVEFTLPQLVTGEYQRLPAFIT
                     PLPSSLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIP
                     DGLIEGARFSQVELNMGPWGILHVDAQLLAISERKVIDGKNETITTPRLSFRFLNVSP
                     AVERELQRIIFSLERDARERANKVRE"
     gene            complement(14471..15082)
                     /gene="emtA"
                     /locus_tag="OPY25_002238"
     CDS             complement(14471..15082)
                     /gene="emtA"
                     /locus_tag="OPY25_002238"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HCS0927844.1"
                     /translation="MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISE
                     KAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEP
                     TTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSD
                     RKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM"
     gene            15253..16167
                     /gene="ldcA"
                     /locus_tag="OPY25_002239"
     CDS             15253..16167
                     /gene="ldcA"
                     /locus_tag="OPY25_002239"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HCS0927845.1"
                     /translation="MSLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRYQ
                     RFAGTDAERLADVNSLASLTSPDTIVMPVRGGYGASRLLDRIDWQALASRQQRDPLLI
                     CGHSDFTAIQAGLLAQANVITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQ
                     GDGPQCDVQGTLWGGNLAMLISLIGTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEY
                     AGILNRQSAIVLGSFSGAAPNEYDAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVT
                     LPIGANATLKNTRQGTQLTLSGHPTLQL"
     gene            16264..17997
                     /locus_tag="OPY25_002240"
     CDS             16264..17997
                     /locus_tag="OPY25_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HCS0927846.1"
                     /translation="MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGIGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISL
                     PSGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFTGLLPFRGFNLRERI
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKV
                     VVPPVGWPVSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNN
                     ELFHPTGSTRLQEGDVLCVIGRERDLPALGKLFSQSPPVSLDQRFFGDFILEANAKFA
                     DVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKEDNVVRK
                     IGVRVAEDEAE"
     gene            complement(18059..19129)
                     /gene="dadX"
                     /locus_tag="OPY25_002241"
     CDS             complement(18059..19129)
                     /gene="dadX"
                     /locus_tag="OPY25_002241"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HCS0927847.1"
                     /translation="MTRPIQASLDLQVMKQNLAIVRRAAPEARVWSVVKANAYGHGIE
                     RVWSALGATDGFAMLNLEEAITLRERGWKGPILMLEGFFHAQDLEAYDTYRLTTCIHS
                     NWQLKALQNARLNAPLDIYVKVNSGMNRLGFQPERAQTVWQQLRAMRNVGEMTLMSHF
                     AQADHPEGIGEAMRRIALATEGLQCAYSLSNSAATLWHPQAHYDWVRPGIILYGASPS
                     GQWRDIADTGLKPVMTLSSEIIGVQTLSAGERVGYGGGYSVTQEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGIRTRTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKVDDVAS
                     AAGTLGYGLLCAVAPRVPFVTT"
     gene            complement(19143..20441)
                     /locus_tag="OPY25_002242"
     CDS             complement(19143..20441)
                     /locus_tag="OPY25_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HCS0927848.1"
                     /translation="MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRESGPAQETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTPFQLKWMWQMLRNCDTRHYM
                     ENKGRMVRLAEYSRDCLKTLRAATGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDA
                     GVPYQLLEASRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLARMAEQAGVTF
                     RFNTPVEKLLYENDQIYGVKCADEIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIVEPDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTDLLQPRRETLEMV
                     VRDLFPRGGHIEQATFWTGLRPMTPDGTPVVGRTRYKNLWLNTGHGTLGWTMACGSGQ
                     LLSDILLGRTPAIPYDDLSVARYRSDFTPTRPQRLHSAHN"
     gene            20764..22296
                     /locus_tag="OPY25_002243"
     CDS             20764..22296
                     /locus_tag="OPY25_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460760.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HCS0927849.1"
                     /translation="MAMIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYQLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARNYITRC
                     EERYGVDEVEKLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRFPAEPQENLLYFMEKNAPLLEPWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTDEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRSKLSSQYNLSNLEPNIQVWNVDLR
                     GDRSLTLRYIPHNRAPLDKGRKEVLKHVHRLWGFDVMLEQQNEDGSVELLERCPPRMN
                     TL"
     gene            complement(22343..23062)
                     /gene="fadR"
                     /locus_tag="OPY25_002244"
     CDS             complement(22343..23062)
                     /gene="fadR"
                     /locus_tag="OPY25_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HCS0927850.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNCFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHD
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            23282..24826
                     /gene="nhaB"
                     /locus_tag="OPY25_002245"
     CDS             23282..24826
                     /gene="nhaB"
                     /locus_tag="OPY25_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HCS0927851.1"
                     /translation="MEISWGRAMWRNFLGQSPDWYKLALLVFLIVNPFIFLANPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVIIGMTSAAHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMVLSLAFCVAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRGEENDMLDDSHIDPHYKTVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLVCGLLTCMLVEKMRWFGYGETLPEKV
                     RDVLQQFDDQSRKKRTRQDKIKLIVQAVIGVWLVTALALHLAEVGLIGLSVIILATAL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSIVAVIIDQHLFAPIIQFVLQASEHAQLTLF
                     YLFNGLLSSISDNVFVGTIYINEAKAAMENGAISLKQFELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLTLIGLLCVEFTLAPATEWMTQAG
                     WLATLS"
     gene            24968..25498
                     /gene="dsbB"
                     /locus_tag="OPY25_002246"
     CDS             24968..25498
                     /gene="dsbB"
                     /locus_tag="OPY25_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HCS0927852.1"
                     /translation="MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLC
                     IYERCALFGVMGAGLVGAIAPKTPLRYVAMVIWIYSAWRGLQLAYEHTMIQLHPSPFM
                     TCDFMARFPDWLPLGKWLPQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAV
                     VIAQAFKPKKRDLFGR"
     gene            25606..25947
                     /locus_tag="OPY25_002247"
     CDS             25606..25947
                     /locus_tag="OPY25_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HCS0927853.1"
                     /translation="MSHLRIPANWKVKRSTPFYTKENVPAALLSHHNTAAGVFGQLCV
                     MEGTVTYYGFANETATEPEVKVVINAGQFATSPPQYWHRVELSDDARFNIHFWVEEDH
                     QGEEMYQQKKA"
     gene            complement(26019..26192)
                     /locus_tag="OPY25_002248"
     CDS             complement(26019..26192)
                     /locus_tag="OPY25_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HCS0927854.1"
                     /translation="MNSEELTHKAEEEIAALISKKVAELRKKTGQEVSEIEFAPRETM
                     KGLEGYHVKIKLL"
     gene            complement(26384..26521)
                     /locus_tag="OPY25_002249"
     CDS             complement(26384..26521)
                     /locus_tag="OPY25_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927855.1"
                     /translation="MSERPDLVDPLPEDEPLPGENIPDTPEGDDPLDPDTQNEVEDPR
                     R"
     gene            complement(26873..27319)
                     /locus_tag="OPY25_002250"
     CDS             complement(26873..27319)
                     /locus_tag="OPY25_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HCS0927856.1"
                     /translation="MSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPL
                     PTWHPLQTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE"
     gene            complement(27412..>27988)
                     /locus_tag="OPY25_002251"
     CDS             complement(27412..>27988)
                     /locus_tag="OPY25_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HCS0927857.1"
                     /translation="HIKEMGSATPEEPVLFIKPETALCDIRQPLAIPADMGAVHHEVE
                     LAVLIGATLRQATEDHVRKAIAGYGVALDLTLRDIQGKMKKAGQPWEKAKGFDNACPI
                     SGFIPVAAFCGDPQNTVIGLNVNGEVRQQGSTADMIHPIVPLIAYMSRYFTLKAGDVV
                     LTGTPAGVGPLLSGDELDIRFNGETLSTRVL"
BASE COUNT         6227 a         7517 c         7396 g         6848 t
ORIGIN      
        1 ccgagagctg ggtccatgat tgtaaactct ctacagctat aatgaatttg aaagtatttc
       61 ttccaatgac accccggtca attaaagtta aaatatcgtg agctacggta gggatatctt
      121 ctgcaaacgg gacgattatt cccgcaccac ttatttcgct tgatctaaaa tcaaaccctg
      181 gggtactttc aatgttttcc ggaataccat actctttaat atgattaagg aattttttaa
      241 tatcgccacg atatggccat cgccattcgc gttcatgtgt ccagtcaatc ttacctggaa
      301 cataagtaac atatctatat tgttcaatca gaggaagagc cgtttcatca agaatacgtt
      361 ccccatatct gccttgcgag catcgagcat tgttatgctg atccaaccca tatatgactg
      421 gccttgcccc ataattaaac atttgctctt taggtaaaac gattgcatat aaaccaatat
      481 tttcatttcg ttctaatcgg cgaacaccag tttctaaata agctgcaatc ggcatatctg
      541 taaagcatac caccggggag tcaccatata cggttcgttg tccatttcgg tatgaccagg
      601 acgagaaaat tttatgactg cgtaaagata atctaagtaa atatttagca tcaatggaac
      661 atgcatggtg ctgattatta aaaccacagt gttcaggtaa ataaatatgg ctaccggtct
      721 ctaaatcaac gtcccgaaaa aaatgaatca aataatcgga taagtcaaat ctgatgttat
      781 ttttcatggg acgccctctt tcaaacagtc tcttttttgc attcctttaa aaccagcacc
      841 atcattttat ataaaaatca tcacgaagta tgcttctttt aacgatgaca tcaaatcctc
      901 cctccttttg catcaactta cgtatccctg aaatggcgag accaagctaa atccacttga
      961 ggttgctcac tgaaaacctc atcccggaac aaactcaacc gcgcttcccc gccacggccc
     1021 tttcgccgaa aaaccgataa tgggtataaa tataccgcta taagctatac ccacacactt
     1081 cacattgttt cttatcgtta atccgatacg cttttttcac attatttctg gcggtatacg
     1141 tcggtgcaaa gtgaatcggg ctcgtttccg cgctcgcgcg taacacaatg atttaccttg
     1201 ctggcggaac gtcaacggac ccgcaaaagc gccttatgcc cctggcggag cgtggtgcaa
     1261 aaaggagaaa aaatacgcgt tatgaataac gaggagacct tttatcaagc catgcgtcgt
     1321 aagggagtga cccgacgcag ctttctcaaa ttctgtagcc ttgccgccac atcgctggga
     1381 ctgggcgccg gaatgacgcc aaagatcgcc tgggcgctgg agaataaacc gcggattccg
     1441 gtggtctgga ttcatggact ggaatgcacc tgctgtaccg aatcctttat ccgttcctcg
     1501 cacccgctag ccaaagatgt gatcctctcg ctgatttccc tcgattatga cgacaccctg
     1561 atggccgccg ccggcgcaca ggccgaagaa gtctttgacg atattaccac tcgctacgcc
     1621 gggaaataca ttctggcggt ggaaggcaat ccgccgttag gagagcaagg aatgttctgt
     1681 atcagcggcg gccgcccgtt tattgaaaaa ctgaagaaag ccgccgcggg cgccagcgct
     1741 attatcgcct ggggaaactg cgcctcctgg ggttgcgtct aggccgcccg ccccaatccg
     1801 acccaggcaa cgcctatcga taaagtgatc accgacaagc cgatcgtgaa agtccctgga
     1861 tgtccaccaa tcccggatgt catgagcgcc attatcacct atatggtgac gtttgatcgt
     1921 ctgccggaac tcgatcgcat gggccgtcca ctgatgttct atggtcagcg tatccacgat
     1981 aaatgctacc gtcgcgccca ttttgatgcc ggtgaatttg tcgagagctg ggatgatgac
     2041 gccgcccgca agggatactg cctgtacaag atgggctgta aagggccaac cacctataac
     2101 gcctgctcct ccacacgctg gaatgacggc gtctcctttc ctatccagtc cggtcacgga
     2161 tgtctgggat gttcagaaaa tggtttctgg gatcgcggct cgttttatag ccgcgtggtg
     2221 gatattcccc agatgggtac ccattcaacc gccgatacgg tggggctgac cgcgctgggc
     2281 gtggtcgctg cgggcgttgg cggtcacgct gtcgccagcg cgctcaacca acgtaaacgc
     2341 cacaaacaac agttagcgca agccgaacaa cagccggaca atgaggataa acaggcatga
     2401 gtaaccagta tcaaacccag ggttataccg ttaacgacgc cggccgtcgt ctgatcgtgg
     2461 acccgattac ccgcatcgaa gggcatatgc gctgcgaagt gaacattgat gagcaaaacg
     2521 tcattaccaa tgccgtttcc tgcggcacga tgttccgcgg gctggagatc attctgcaag
     2581 gccgtgaccc acgtgacgcc tgggcgtttg ttgaacgtat ttgtggtgtc tgtaccgggg
     2641 tacatgctct ggcgtcggtg tacgctatcg aagatgcgat tggtatccag gtaccggata
     2701 acgccaatat tatacgtaac atcatgctgg ctacgttgtg gtgccacgat catttggtcc
     2761 atttttatca gttagccggc atggactgga ttgatgttct gaatgcgctg aaagccgatc
     2821 cacgcgccac ctcgcagctg gcgcaaagcc tttccgcctg gccgatgtca tcgccgggct
     2881 acttctttga cgtacaaaat cgattgaaga aatttgtcga tggcggccag cttgggatat
     2941 tccgtaacgg ctattgggga catccacagt acaaactgtc gccagaggct aatctgatgg
     3001 gttttgccca ctatcttgaa gccctcgact tccagcgcga gatcgtcaaa atccatacca
     3061 tatttggcgg taagaacccc catcctaact ggatcgtcgg cgggatgccg tgcgcgatca
     3121 atctcgatca aagcggcgcg gtcggggcta tcaatatgga gcgcctcaac ctggtgcagt
     3181 cgatcatcac ccgcaccgcc gacttcatta acaacgtgat ggttccggac gcgctggcta
     3241 tcggccagtt caataaagca tggagtcaaa ttggcaccgg tctgtcggat aaatgcgtgc
     3301 tgagctacgg cgcatttccg gacattgcca acgacttcag ccagcaaagc ctgttaatgc
     3361 cgggcggcgc ggtggtcaat ggcgatttta aaaatgtcat gccggtagat ttggccgatc
     3421 cgcagcagat acaggagttt gtggatcatg cctggtaccg ctatccggac gatcggctgg
     3481 gccgtcatcc ttttgacggc attaccgatc cctggtacaa cccgggtgat gtcaaaggca
     3541 gcgatacgca tatccagcag ctcaacgagc aggaacgcta ctcctggatt aaagcgccgc
     3601 gctggcgggg tcatgccatg gaagtcggcc cgcttgcccg aacgcttatc gcgtatcaca
     3661 aaggggatgc cgccaccata gagtcggtag atcgcatgat gtctgccctt aaactgccgc
     3721 tctccggtat ccagtctacg cttggccgta ttttatgccg cgcgcacgaa gcgcaatggg
     3781 ccgtcggtaa gctgcagtat tttttcgaca ggcttatgac caacctgaaa aacggcgacc
     3841 tggccaccgc caataccgag aaatgggaac cggccagttg gccgcagcac tgccgcggca
     3901 tcggttttac cgaagcgcct cgtggagcgt tgggacactg ggcgtcaatc cgcgatcaga
     3961 agattgaact ctatcagtgc gtagtcccca ccacctggaa cgccagccca cgcgatccta
     4021 aaaaacagat cggcgcctat gaagcggcat tgatgggaac gcaaatggcg attcccgacc
     4081 aaccgttaga aatcctgagg acgctgcaca gcttcgaccc ctgcctcgcc tgttcaaccc
     4141 acgtgctcgg cgacgacggc agcgaactga ttgccgtcca ggtacgctaa gcgttaagga
     4201 aaagaacgat gactggaaag ctatctccac gcgtcgggga ggcgcgtgat actgccgtca
     4261 gccactatgt gtttgaagcg ccggtacgcc tgtggcactg gctaacggtg gcctgcatgt
     4321 tggtactgat ggtaacaggc tacttcattg gccgaccgct gccgtcggtg agtggcgagg
     4381 cgacctatct gttttacatg ggctatatcc ggctgatcca ctttgccgcc gcgatgatct
     4441 ttatcgtgtt actgctgggg cgaatttatt gggcctgtgt cggcaaccgc tattcgcgag
     4501 agctgtttat cgtcccggtc tggcgtcgca gttggtggca aggcgctttc tccgtggtcc
     4561 gctggtatct gtttctggag aaaaaaccgg ggagcgacat cggacataat cctatcgcgc
     4621 aggccgcgat gttcggctat ttcctgttat cggtatttat gatcctcacc ggtttcgctc
     4681 tgtttggcga gcatagccag tatgccatct ttgcgccgtt ccgctatgtg gttgaatttt
     4741 tctactggac cggcggcaac tccatcgata ttcacagctg gcaccgactg ggcatgtggc
     4801 tgatcgccgc cttcatcgtc gggcacgttt acctcgctat ccgggaagac attatgtccg
     4861 acgatacggt gatctccacc atgatcaatg gctatcgcag ccacaaattc cccaaaccgc
     4921 acgacaagga gccctcatga atgcgcaacg tgtagtggtg atgggattag gaaacctgct
     4981 gtgggccgat gaaggattcg gtatccgggt cgcggagcgt ttgtatgccc gatatcactg
     5041 gcctgaagag gtagaaattg tggacggcgg tacgcaaggg ctaaacctgt taggttatgt
     5101 tgagcaagcc agccatctcc tgctccttga cgcgatcgat tacggcctgg cgccgggcag
     5161 cctgcgaacc tatgccggcg agaaaatccc cgcgtatctc agcgccaaaa aaatgagcct
     5221 gcatcaaaac agtttttccg aagttctggc gctggccgac atccgcgggc atctgccctg
     5281 tcacattgcg ctggtcggcc tgcaaccggc gctactggac gactacggcg gtagcctgag
     5341 cgaaatagct cgcagccagc taccggcggc agaacaggcc gccctggcgc aactggccgc
     5401 ctgggggatc gtaccgcagg caaatgaggt cgcacgctgc ctgaactata aatgcctgtc
     5461 gatggaaaat tatgagggag tgcgcatacg tcagtatcag acacgtctgg agggcaaaag
     5521 aagtggcgaa tgacaccccg ttctctgcgc tatggcaacg cctgttaacc cgtggatggc
     5581 aaccggtaga ggcttccacg gtagacgact ggatcaaacg gattggagat ggcgtcatcc
     5641 tgttaagtag cgatccgcgg cgtacgccgg aagtcagcga taacccggtg atgattgccg
     5701 aactcctgcg tgagttcccg cagtttgact ggcaggtgac ggtggccgac cttgaacaaa
     5761 gcgaagctat cggcgatcgc tttaatgtac gtcggtttcc ggcgacgttg gtttttacag
     5821 acggcgagct acgcggcgcg ctcagcggca ttcatccctg ggctgaactg ctcacgctga
     5881 tgcgttcgat ggttgacact cccgcagcgc aggagacagc acaatgagca acgccttttt
     5941 tcatctgctg gggccaggca cgcagcctga tgacgccagt ttctcgatga atcccctacc
     6001 gctcacctgt caggtcaatg gcgacccaag tatggcggcg ctggaacgct gcgctcacag
     6061 cccggcggtg atggcattgt tgaccgatct gcgaggtcag cttgcccggc gcatcccgga
     6121 agtcggcgac gtgctgggat gggagttatc tcccctgaat gccgatgatc tctcattcct
     6181 caatacgcta ttgggcgaag gcgaagtctc ggtacgcatt cagcatccgg acgggagtga
     6241 aagcgagatc caggagacca tcttctgcgg cctgtggcgg gtacgccatc tgcataaccg
     6301 acgtctgctg acggatcgtc tggaagcggg tagcgcgccc ctgacattgt ggcaagcggc
     6361 gactgccgat acgctgcctg acgactctct gctgcctccg cctgtcgctg gcctgatgaa
     6421 tggactgccg ctggcccatg agttattggc gcacgtacgc gatccggcgt tgcaacctca
     6481 cagcatcaat ttgacccaac tgccgctcag cgaggccgat cgtctttttc tggcgcgttt
     6541 atgcggacac gggaacatcc agattcgcat ctccgggtat ggcgaaagcc aaatcaacgc
     6601 cacagcattg cgccatctct ggcatgtgcg ctgtctggac gcccttaaag ggccgttgct
     6661 cgatagctat gagatttgtc ctttgccgga gctggtactg gcggccccgg aagatctggc
     6721 cgattcgcgc cagcgcctgg atgaagtctg ccgatggctg gagacgcgct agcgctctca
     6781 acaggaacgt caccggtgtc cggtattgat tagcttttta ctctctttct gcctacagga
     6841 gttagcatgt gggatgtcat tgacttatcg cgctggcagt ttgcgctgac cgcgctgtat
     6901 cactttttat ttgttcctct tacgcttggg ctgatttttt tgctggccgt catggagacg
     6961 atctatgtgg tgacggggaa aaccgtctac cgcgatatga cgcgtttctg gggcaagctc
     7021 ttcgggatca attttgctct cggtgtggct atcggcctga ccatggagtt tcagttcggg
     7081 actaactggt cgctctattc caactatgtg ggcgatatct tcggcgcgcc gctggcgatg
     7141 gaagcgttac tggccttctt tctcgaatcc acttttgtcg gcctgttctt tttcggctgg
     7201 cagcggctga ataaatacca acacctgctg gtcacctggc tggtggcctt cggctccaat
     7261 atttcagcat tatggattct gaatgccaat ggctggatgc agtatcctac cggcgctcat
     7321 ttcaacatcg atacgttacg gatggaaatg agcagcttca gcgatctggt ctttaacccg
     7381 gtgagccagg tgaaattcgt ccataccgtc atgtccggtt atgtcaccgg cgccatgttt
     7441 attatgtcta tcagcgcctt gtatctgcta cgtggccgcg agcgtgaggt ggccttgcgc
     7501 tcgtttgcta tcggctcagt attcggcacc ctggccattc tgggaaccct gcaactgggc
     7561 gacagttcgg cctacgaggt cgcccaaatt cagccggtga aactggcggc gatggaaggc
     7621 gaatggcaaa ccgaacccgc gcccgcgccg tttcatctga ttgcctggcc gcagcaggaa
     7681 caggagcgta atgcatttgc cgtgaagatc cctgctctgc tgggtattct ggccacccat
     7741 tcgctggata cgccggttcc ggggttaaaa aacctgatgg acgacgctct gccgcgcctg
     7801 aagcgtggcc gggaggcctg gctactcatg caggagatag cgcaaggcaa tcgctcgccg
     7861 caggtactga atgcgtttca cgccgttgag ggcgatctgg ggtacggcat tctgctggcg
     7921 aaatatgccc cggatatgaa ccatgtgacg ccggagcagt atcgtgcggc ccagcgtggc
     7981 gctattcctc aggtggcgcc ggtgttctgg agtttccgta ttatggtcgg ctgcggttcg
     8041 ctgctgttag tggtgatgtt gattgcgttg atacagacgc tgcgaatgcg tatcgaccag
     8101 catcgctggg tattgcgtat gacgctgtgg agcctgccgt taccgtggat tgccattgaa
     8161 gccggttggt ttatgacgga gtttggccgt cagccctggg cgattcagga cattctgccg
     8221 acctggtacg ctcactccgc gctgacgccg ggccagttgg ccttctcaat ggggcttatc
     8281 ctcggacttt acaccctgtt tttaatcgcg gaagtctatc tgatgcagaa gtacgcgcgt
     8341 cttgggccga gcgccatgca acatcaacaa caagcgcaac aacagggata aaggagacaa
     8401 tcatgttgga ttatgaaacg ttgcggttca tttggtggct gctgatcggc gtcatcctag
     8461 tggcatttat ggtaactgac gggtttgata tgggtgtcgg ttgcctgctc ccgctgatag
     8521 cgcgcaacga tgacgaacgc cgggtattga tcaatagcgt cggcgcccac tgggaaggaa
     8581 accaggtatg gttgattctc gcgggcgggg cattattcgc cgcctggcca cgggtctatg
     8641 ccgccgcgtt ttccggtttt tatgtggcga tgatcctggt gctgtgtgcc ctcttccttc
     8701 gcccgctggc ctttgattat cggggtaaaa tcgccaatgc ccgctggcgc gcgctgtggg
     8761 ataccggtct ggttatcggc agcctggtgc cccccgttgt attcggcatc gcgttcggca
     8821 acctgttttt aggcgtgccg tttgccttca cgccgcagct tcatgttgac tattttggca
     8881 ccttctggca gttactctcg ccctttgccc tactgtgtgg attattgagt ctgtcgttgg
     8941 tgattatgca aggaggcgtc tggttacagt tgaaaacgga gggcgttatt cgtcaacggg
     9001 ctctgtcggc cacccgccac agcgcgctgc tgatcgtgat ctgcttcctg ctggccggtt
     9061 actggctgtg ggccggcgtt gatggctttg tcttactcac gcaggatgcc aacggccctt
     9121 ccaatccgct cttaaaaggc gtggcgatac tccctggcgc atggatgaac cactttatac
     9181 gctcgccgct actgctcatc atcccgttgc tcggtatgat cctgccgatt ctggctttct
     9241 atgcctgcct tcgcggtcag actattcgtg gatttctgtt cgcttccctg acccaggcct
     9301 gcgtcatctt taccgccggc ataacgctat ttccttttgt gatgccgtcg agtgttagtc
     9361 ctctctccag cctgacggtg tgggacagca cctccagcca gatgacgctc gaaatcatgc
     9421 tggtgattgt gctgattttt ctgccaatcg tactgctcta tacgctgtgg agctattaca
     9481 aaatgttggg gcgtatcaac ctggagaccc tccgccgcaa cgatcatgaa ctttattagg
     9541 gagcgagagc gatgtggtat ttactgtggt ttgtcggcat tctgctgatg tgctcactgt
     9601 cgacgctggt gctggtgtgg cttgagtcgc gtcaacaata aagaggtaaa ccggggtcag
     9661 agccgtctga ctccggttat ttttatcttt ttacgcgcct ggcgaagacg tttccccgcc
     9721 gacaggacga cataacattg atacatgtcg ttatcataat ctttactttt agaggtgcgt
     9781 cataattatg acaaatagcc gccttgcaca tatcacgcat atttaagcaa ttaattgcat
     9841 aattagcgat atatcacctc ttatagcgga tagttaacca cttctcatcc aaaatcataa
     9901 cgaaaatcca actgcctgcc atttttgatc tgagttaatt gtttaaaaaa agtgttaaat
     9961 ttatcgctac atggtgtgat ctactatgta ccacggtcaa ttaaagaaca tattactttt
    10021 atcactaagg tttatcatgg ataagttatc ttacgcttca gatagcagca catctgcctg
    10081 gaatacctac ctgcaacaaa tcgagcgtgt ggccccttat ctgggcgagt tatcccccta
    10141 ggtggatact ctgcgccacc caaaacgcgc tctgatcgtc gatattccgg tacaaatgga
    10201 tgatggcact attcgtcatt tcgaaggata tcgcgtgcag cacaacctct cccgaggtcc
    10261 gggtaaaggc ggtgttcgct accatcctga cgttgatctc aatgaagtga tggccctgtc
    10321 agcatggatg accatcaaat gtgccgcgct gaatctgccg tacggcggcg ccaaaggcgg
    10381 catccgcgtc gatccgttct cgctgtcgga aggtgaactg gagcgtttga cccgccgcta
    10441 taccagcgag atcggcatta tcatcgggcc gcagaaagat attcctgcgc cggatgtcgg
    10501 caccaacggt aaagtgatgg cctggatgat ggatacgtat tccatgaatc atggcacgac
    10561 ggtcactggc gtcgtcaccg gtaagcctat ccatcttggc ggttcgctgg gtcgtgaaaa
    10621 ggcgacgggg cgcggcgttt tcgtcagcgg gctggaagcc gcgcgtcggg cgaatatcgc
    10681 cgttgaaggc gctcgcgttg cggttcaggg ttttggtaac gtcggcagcg aagccgcgcg
    10741 tctgtttgca ggcgctggcg cccgtgtcgt ggcgattcag gatcataccg cgacgctgtt
    10801 taacgccacc ggtattgaca tgaaggcgct cacggcatgg cagacagaac acaaacagat
    10861 agccggtttc ccgggcgcgg aaactatcgc cagcgatgcg ttctggcgtc tggagatgga
    10921 tattctgatc ccggcggcgc ttgaaggcca gataactcgt cagcgcgcgg aagccctgac
    10981 gtgtaagctg gtgctggaag gggctaacgg cccgacctat ccggatgctg atgatgttct
    11041 ggccagccgt ggtatccttg tggtgcctga cgtggtctgt aacgcaggcg gcgtaaccgt
    11101 cagctacttc gaatgggtac aagatatggc cagcttcttc tggagcgaag aagagatcaa
    11161 cgcgcgcatg gacaaaatca tgaccgacgc gatcgtccat gtctgggaga aagcggctga
    11221 gaaatcctgt tctctgcgca ccgcagccta tattgtcgcc tgtgagcgca ttctgctggc
    11281 ccgtaaagat cgcggtatct atccaggtta aggcgacaaa tcattgcgct aaaatccacg
    11341 tcccggcgtg gattttttgt ctgtataccc cgttttccac gcgcgcgccg ataaattctg
    11401 tctcaataaa atgtctgttt gttcgcaaaa tagcggttca atcacgcgta tctggtcatc
    11461 gtagactaag gttttgtcat ggtaaatgcc gttggctttg gctcactgct aaggagataa
    11521 cttgatgata cccccagaga ttcgccgttc tgttctacta cagaaagcca taaaactggc
    11581 gctggcaggg acgctgctga cgtttgcatc gttttcggcg actgccgcag acccgtcttc
    11641 cgacactgaa actccgcagc cgccggatat tttgcttggc ccgctcttta atgatgtcca
    11701 gaatgcaaaa ctcttccccg atcagaaaac ctttgctgac gccataccta atagcgatcc
    11761 gctcatgatt cttgcggatt atcgtatgca gcggaactag tccggcttcg atttgcgtca
    11821 ttttgttgat gttaacttca ccctgccgaa agcgggtgaa aaatatgtcc cgcctgccgg
    11881 gcaatcattg cgtgaacata ttgatggcct gtggccggtg ctgacccgtt caactaaaaa
    11941 cgtcgaaaag tgggactcgc tcttgccgtt gcctgaatcc tatgtcgtac cgggtgggcg
    12001 attcagggag atttactact gggacagcta ctttacgatg ctggggctgg cggaaagcgg
    12061 gcactgggat aaggtggcgg atatggtagc gaactttggt tacgaaattg acgcctgggg
    12121 gtatattcct aacggcaacc gtacctacta cctgagtcgt tcacagccgc ctttctttgc
    12181 gtttatggtt gaattactgg tgcaacatga aggtgacgat gcgctgaaag aatacctgcc
    12241 gcaactgcaa aaagagtacg cctactggat ggagggcgtt gagacattgc agccagggca
    12301 acaaaaccaa cgcgtcgtca aactggagga cggcagcgtt ctcaaccgct actgggacga
    12361 tcgggatacg ccccgccctg aatcctgggt tgaagatatc gctaccgcca aaagcaaccc
    12421 cagccgcccg gcaacggaga tctatcgaga cctccgatct gctgccgcct ccggctggga
    12481 tttcagctcc cgctggatgg ataatccgca gcagctcagt accattcgta ccaccacgat
    12541 tgtccctgtc gatcttaacg ctctgctgta tcagctggag aaaaccctcg cccgcgccag
    12601 cgctgcggcg ggcgatcggg ccaaagcctc gcaatatgac gcgctggcca acgcgcggca
    12661 aaaagccatt gaaatgcatc tgtggaataa caaagagggt tggtatgccg actacgatct
    12721 gcagaacaat aaaatccgtg accaactcac cgctgccgcg ctgttcccgc tctatgtaaa
    12781 cgccgccgcg aaagatcgcg ccgcgaaagt ggcagcggcg gcccaggcgc atctgctaca
    12841 gcctggcggg ctggctacca cctcggttaa aagcggacag cagtgggatg cgccaaatgg
    12901 ctgggcgccg ttacaatggg tcgctgccga aggattgcaa aattatgggc aggatgacgt
    12961 ggcaatggaa gtcacctggc gctttttaac caatgtgcag cacacctacg atcgcgagaa
    13021 aaaactggtc gaaaaatatg acgtcagcag taccggaacc ggcggtggcg gcggcgaata
    13081 tccccttcag gacggctttg gctggagcaa cggcgtgacg ctgaaaatgc tcgatctgat
    13141 ttgtccgcag gaaaaaccgt gcgatagcgt accgtctact cgtccggcat cgttaagcgc
    13201 aacgccgaca aaaacgccgt ctgcagcgac gcagtaacgc gtgtttatag taggttgacc
    13261 cggcgctgac cgggtcaacg cttacacgtt ctgcagcggt tagccgcgtc gcagaaggcg
    13321 gaaaatcacc agcaccacaa tcgcgcccac cacggcgacc aggaaactgt gcagattaaa
    13381 gccgctgata ctgccgccaa taccaaacat cgtcgccagc catccgccaa cgaccgcccc
    13441 gacgataccg agaatacagg tcaggataaa tcccccgcca tcgcgccccg gcataagcaa
    13501 tttggcgata acgccggcaa tcaaaccaaa aacaatccag gcgataattc ccatttgcga
    13561 accctctttc cagtaaaaac gttttaagta taggcaaagt cgagcgtcgc atttctgaac
    13621 actgatttat ctcgcggaca taaaaattta tttatcgcta ttaagttctt tctactgatg
    13681 ccgataaccc aacgatagtc tgcgtatcag gggttatttc gtgtgagtgg ttacaatgag
    13741 cagttcctga aaaaaaatcc attagcgata ttaggcgtgc tacgggattt aaataaaaat
    13801 caggttccac tgcgtatttc atgggcgcat ggtcaattca ttagtaaaat tttggcggta
    13861 gccccggaaa aactcatcgt ggattacggc agccaggaat ataaaaatag cgccgtatta
    13921 cgcgccgggc aggtagccat tatcgcagaa acacaaggcg caaaagtcga gttcacgttg
    13981 ccgcaactcg ttacaggtga atatcagcgg ctgccggcct ttatcacgcc cctgccgtca
    14041 tcactgtggt ttgtccagcg ccgggagtat tttcgcattg gcgcgccgct gtatccgcct
    14101 tattacggcg tcaccacgct accggacacc cgtacgttac gttttcgcct gtttgatctt
    14161 tccctgggcg gcatgggcgc gctactggaa tccgccatcc ccgacggact aatcgaaggc
    14221 gcacgctttt cgcaggttga actgaacatg gggccatggg ggattcttca cgttgacgcc
    14281 cagcttctcg ccatcagcga gcgtaaggtg attgatggga aaaatgaaac gatcaccact
    14341 ccccgcctga gctttcgttt ccttaacgtt agcccggcgg tggagcggga gttgcagcgg
    14401 attatttttt cgcttgagcg cgacgcccga gaaagagcga ataaagtgcg agaataatct
    14461 tcacgctaaa ctacatggcg tccagcgcct gctgaagctt ccagatatag cgcggcgcct
    14521 gcggcgcggg atgattatca acaacatgtt caaaaaactc gtcagcatcc agatcgttaa
    14581 ttttttctat cgccttcttc ctgtcggatg aaaaagtacg caataacgcg cctgcgccgt
    14641 tagcataaga gacgaccagc gcatattgca tcacctgcgg atctttgatg ccggccagcg
    14701 gcccattttc cagaatgctc agatacgccg cgcccattga gatgttacgc tcagggtttt
    14761 tcagctcgct ggtggtcggt tcgccacgcc agcccatacg acggtaaacg tcgcgcccgg
    14821 aagtcgacgc ctttaactgc atcaggccaa tcgcattgga cttactgacc gcgttagggt
    14881 tgccgccgga ttcaatggcg ataatcgcgg tgattaaatg tggatcaacc ccccatgccg
    14941 ccccggcttt ttcactgatg ggcatccact gcatcgcacg ctttacaggc acttcggcat
    15001 tccacggtgg attcctgtaa tcctgttttg agctacagcc agccagtatt actaccaaaa
    15061 aagcaaacca tcttaatttc acgtcatcta tccttatagc cgtaacttat ctgccgaaga
    15121 ggttataccg ccccggccag gtacttaggt tgcctccctg gtgcgcatcc agaaacgtcg
    15181 cacaacgagg gacatcgcct aatatatgcg gcatgatata catttgcatt ctattgtcag
    15241 caaggaatta ccatgtctct gtttcattta atcgccccct cgggctactg tattaaccaa
    15301 caggccgcgt tacgcggcgt tcagcgcctg actgacgcgg gtcatcaggt ggagaatgac
    15361 gaggtgattc gtcgccgcta tcagcgtttt gccggtacgg acgcggaacg gctggccgat
    15421 gttaattcgc tggcctcgct aacttcgccg gatacgatcg tcatgccggt tcgcggcggc
    15481 tatggcgcca gccgcttgct ggatcgtatc gactggcagg cgctcgcctc ccggcaacag
    15541 cgcgatccct tactgatttg cggtcatagc gattttacgg cgattcaggc tggactactg
    15601 gcgcaggcca atgtcatcac ctttagcggt cctatgctgg cggcaaattt tggcgccgaa
    15661 acgctgaata cgttcaccga gcaacatttc tggctggcgc tacgcaaggc gcaatttacc
    15721 gtagagtggc aaggcgacgg ccctcagtgc gacgtacagg gcaccttatg gggcggaaat
    15781 ctggcgatgt tgatttccct tatcggtacg ccctggatgc cgactatcga taaaggaatt
    15841 ttagtgctgg aagatgtcaa tgagcatcct ttccgggtgg agcgtatgct tttgcaactg
    15901 gagtacgccg gaattctaaa ccgtcagagc gccatcgttc tcggcagctt tagcggcgcg
    15961 gcgcccaacg agtatgacgc cggctattct ctggagagcg tctacgcgtt tttacgttcc
    16021 cgtctgtccg ttccgctgat taccggtctc gacttcgggc atgaacagcg tacggtgacg
    16081 ctccctatcg gggcaaacgc aacgcttaaa aatacgcgcc aggggactca actcacttta
    16141 tctggtcatc ctacgctgca attgtaaaaa aagtccccga caggctaagt aaaacgctgc
    16201 cctggccgtt attatgttaa tgttaaataa tacgaagtcg tgtgagtcag gagatataaa
    16261 acgttggatg ctgcaacaat tattagtcta tttattttag gttccatcct tgtaaccagc
    16321 agtatcctgt taagttcatt ctcatcgcga ctgggtatcc cgattctggt cattttcctc
    16381 gccattggga tgttagcggg tgtggatggc attggcggta ttcctttcga taattatcct
    16441 ttcgcttata tggtcagtaa cctggcgctg gcgattattt tactcgatgg cggcatgcgc
    16501 acccaggcca gctctttccg ggtagcgctg ggccccgcgc tgtcgctggc gacgctcggc
    16561 gtactgatca cgtcggggtt aacaggtatg atggccgcct ggctgtttca tctggatctt
    16621 atcgaaggtc tgcttatcgg cgcgatagtc ggttccactg acgccgcagc ggtcttttct
    16681 ctgcttggcg gcaaagggct aaacgaacgt gtaggctcca cgctggagat cgaatcggga
    16741 agtaacgacc cgatggccgt ttttttgacc attacattaa ttgagatgat ccagaaacat
    16801 gaaaccggcc tggactggat gtttgccgtc catattatcc agcagttcgg tctcggtatt
    16861 gtttttggcc tcggcggcgg ttacctgcta cagcagatga tcaaccgtat ttctctgccc
    16921 agcggcctgt atccgatgct ggcgctcagc ggcggtattc tgatttttgc tttgacgacc
    16981 gcgcttgaag gcagcggcat tctcgcggtc tatctgtgcg gattcctgtt aggaaaccgt
    17041 ccgattcgca accgttacgg catcctgcaa aactttgacg gactggcctg gctggcgcag
    17101 atcgccatgt tcctggtcct gggactgctg gtgacgcctt ccgatctgtg gccgattgcc
    17161 gtccctgcgc ttattctctc tatctggatg attttcttcg cccgcccatt gtcggtattt
    17221 accggcctgc tgccttttcg cggcttcaat cttcgggagc gcattttcat cagttgggtc
    17281 ggactgcgcg gcgcggtgcc gattattctc gccgttttcc cgatgatggc cgggcttgaa
    17341 aacgctcgcc tgttctttaa tgtcgctttc tttgtggtac tggtgtcgct gctcctgcag
    17401 ggaacatcgc tgtcatgggc ggcgaagaga gccaaagtgg tcgtgcctcc ggttggctgg
    17461 ccagtatcgc gcgtggggct tgacatccat cctgataatc cgtgggaaca attcatctat
    17521 cagttgagcg ccgacaaatg gtgcgtcggc gcggcgttgc gcgacctgca tatgccgaac
    17581 gaaacccgca ttgccgcgct atttcgcaat aatgaactgt ttcaccccac gggtagcact
    17641 cgcctgcagg aaggcgacgt actctgcgtg attggccggg agcgcgatct gccagcgctg
    17701 ggcaaattgt ttagccagtc gccgccggtt tcgttagatc agcgtttctt tggcgatttt
    17761 atcctcgaag cgaacgcgaa attcgccgac gtggcgctta tctacgggct ggaagaagga
    17821 acggaatacc gggataaaca acaaaccctc ggtgaaatca tacagcagct gctgggcgct
    17881 gcgccggtcg ttggcgatca ggtggagttt ggcggcatga tttggacggt agctgaaaaa
    17941 gaagataacg tggtacgcaa gattggggta cgcgtcgccg aagacgaagc agaataaggt
    18001 cgccggacaa cgtcgacccg cccccggtgg accggtcgac gccttagcct gagttaggtt
    18061 acgttgtcac aaacggcacg cgcggcgcta cggcgcacag tagcccatag cccagcgtgc
    18121 ctgccgcaga ggcgacatca tcgaccttaa tttctttgcc ccataattca accggcgtgc
    18181 cgattcccgc ctgcggacac ggcgtcaaat ccaccgccag catatccatt gaaacggtgc
    18241 ctactgttct ggtacggata ccgtccacca gcacgggcgt cccggtcggc gcatggcgtg
    18301 gatagccatc ggcataaccc gccgcgacga tgccaatgcg ttgttcctga gtcacagaat
    18361 accctccgcc atagcctact ctttcacccg cgctcagcgt ctgcacgcca ataatttcgc
    18421 tactcagcgt catcacgggt tttagtccgg tatcggcaat atcccgccac tgtcctgacg
    18481 gcgacgcgcc gtacaaaata atgcccggcc tgacccagtc ataatgcgcc tggggatgcc
    18541 acagcgtcgc tgccgaattt gataacgagt atgcacactg caggccttct gtcgccagcg
    18601 caatacgtct catcgcctcc ccgatacctt ccggatgatc ggcctgagca aaatgtgaca
    18661 tcagggtcat ttcaccgaca ttgcgcattg cccgcaattg ctgccagacg gtctgcgccc
    18721 gctcaggctg aaaaccgagt cggttcatac cgctgttgac tttgacatag atatccagcg
    18781 gcgcgttaag ccgcgcattt tgcagcgctt tcaactgcca gttactgtgg atgcaggtgg
    18841 tcagccgata agtgtcatac gcctccaggt cttgcgcatg gaaaaacccc tccagcatca
    18901 atatcggccc tttccacccg cgctcacgca gggtaatcgc ctcttcaagg ttgagcatag
    18961 cgaaaccatc tgtggcgccc agcgcgctcc agacgcgttc aataccgtgg ccgtaggcgt
    19021 tggctttcac taccgaccag acgcgcgcct ccggggccgc ccggcgcaca atagccaaat
    19081 tttgtttcat tacctgtaaa tcaaggctgg cctgtatagg gcgggtcatt tcacttcctt
    19141 tatcagttat gcgcgctatg caaacgttgc gggcgggtgg gcgtaaaatc ggaacggtat
    19201 cgcgccacgc tcagatcgtc gtagggtatc gctggcgtac gacccaacaa gatatcgctt
    19261 aacaactggc ctgaaccgca ggccatcgtc cagcctaagg tgccgtgtcc agtattaagc
    19321 cacagatttt tataacgggt gcgtcctact accggcgtgc cgtccggcgt catggggcgc
    19381 aggccggtcc agaatgtggc ctgctcaata tgaccgccgc gcggaaaaag atcgcgcaca
    19441 accatctcca gcgtctcgcg gcgcggttgc agtaagtcgg tattaaagcc cacgatttcc
    19501 gccattcccc ccacgcgaat acgcttatca aaacgcgtaa tagcgatttt gtaggtttca
    19561 tcaagaatcg tcgataccgg cgcgccgtct ggctcgacga ttgggatggt taatgaatag
    19621 cctttcagcg gatacaccgg gatatcaaca atgcctttaa gcatcgccgt cgaatacgat
    19681 ccaaacgcca tgacatacgc atctgcttta atgatctcat cggcgcattt cacgccgtaa
    19741 atctgatcat tttcgtacag taatttttcc acgggagtat taaagcgaaa ggttacgccc
    19801 gcctgctccg ccatgcgcgc cagacgctgg gtaaagagct gacagtcccc ggtttcatca
    19861 ttcggtaagc gcagcccgcc ggttaattta tgcgcaacct cagccagagc gggttcaact
    19921 tccgccagtc ggctggcttc caggagctga tacggcaccc cggcatcttc cagcacggcg
    19981 atatcacggg tggcgttctc atactgttgc gcggtgcgga agagttgtag cgttcccccc
    20041 tggcggcctt catattcgat accggtcgcg gcgcgtagcg ttttcaggca gtcgcgacta
    20101 tattccgcca gacgcaccat gcggccttta ttttccatat aatgccgggt atcgcagtta
    20161 cgcagcattt gccacatcca cttcagttga aatggggtgc catccagacg caccgccagc
    20221 ggcgcatggc gctggaacat ccattttatc gccttcagcg gtacgccagg ggccgcccag
    20281 ggtgccgcat atcccggtga aatttgtccg gcattcgccg cgctggtttc ttgcgccggg
    20341 ccggattcgc gatcgatgac ggtgacatca tgccccgcct gactcaagta ccaggcgctg
    20401 gtcacgccaa ctacgccact ccccaggatg acaactcgca tagccactcc gttaatagta
    20461 aaagaacaat cttctgatta catcttgata actcagatga aaatattatt caacatatga
    20521 cttttttatg gtgacgtgct tcacatatac cctaaagaca agcgatccca ttggtttggg
    20581 atctcctgct acgcggcatg gctatacagc ataaaatgat gccaataccc gattttttgc
    20641 cgttcaatgt ggaggaaatc gcaaagaaaa gttttcacga tcaagtcgtt ttttaacatg
    20701 gtgttctatg cttgaaagga ggcgctccat acagagagcg tcgccaacaa tgagggtgcg
    20761 cgaatggcaa tgattgattc catgaacaag gacaccacac gtttgagcga tggccccgac
    20821 tggacatttg atctgctgga tgtttatctg gcagagatag accgcgtggc gaaactctac
    20881 caactggata cttacccgca ccaaattgaa gtcatcactt ccgaacagat gatggacgcc
    20941 tactccagcg tcgggatgcc gatcaactat ccgcactggt cgtttggcaa aaagttcatt
    21001 gagacggaac gtctgtataa gcatggtcaa caaggactgg cttatgaaat tgtgatcaac
    21061 tctaatccct gcattgccta cctgatggaa gagaacacca tcaccatgca ggcgctggtc
    21121 atggcgcacg cctgttacgg ccacaactcc ttttttaaaa ataattatct cttccggagc
    21181 tggacggatg ccagctctat cgtcgattac ctgattttcg cccggaatta cattacccgc
    21241 tgtgaagaac gctacggagt ggatgaagta gaaaaactgc tcgactcctg ccacgcgctg
    21301 atgaattacg gcgtcgatcg ctataagcgc ccgcagaaaa tctcgttgca ggaagagaaa
    21361 gcgcgacaaa aaagccggga agagtatcta caaagccagg tgaatatgct gtggcgcacg
    21421 ctgccaaaac gcgaggaaga aaaaactgtc gccgaagcac gccgctttcc tgctgaaccg
    21481 caggaaaacc tactctattt tatggagaaa aacgccccgt tgctcgagcc gtggcagcgc
    21541 gaaattctgc gcatcgtgcg taaagtcagc cagtattttt atccgcagaa acagacgcag
    21601 gtcatgaacg agggctgggc gaccttctgg cactacacca tcctgaacca tctgtatgat
    21661 gaaggcaaag tgacggaacg ctttatgctg gagtttttac acagccatac caatgtcgta
    21721 tttcagccgc cctataatag cccctggtat agcggaatta acccctatgc gctcggcttt
    21781 gccatgttcc aggatatcaa acgtatttgt cagtcgccca cggatgaaga taaatactgg
    21841 tttccggata ttgccggttc cgactggctg gaaacgctgc acttcgccat gcgcgatttt
    21901 aaagatgaaa gctttatcag tcagttcctg tcgccaaaag tgatgcgtga tttccgtttc
    21961 ttcacggtac ttgatgatga caggcataat tatctggaga tctccgccat tcataacgaa
    22021 gaaggttatc gggagattcg atcaaaactg tcgtcacagt ataacctgag caacctggag
    22081 ccgaatattc aggtctggaa tgtggattta cgcggcgaca gatcgctgac gttgcgttat
    22141 atcccgcata accgcgcgcc gctggataaa ggccgcaaag aggtgctgaa acatgtgcat
    22201 cggttatggg gctttgatgt gatgctggag caacaaaatg aggatggcag cgtagaactg
    22261 ctggagcgtt gtccgccgcg catgaacacg ctgtaatcga gatgctgccc ggtagtgttt
    22321 gcgtctaccg ggcatcgcgg gattatcgtc cctgaatcgc taaatcgccg ggcagatttt
    22381 tctgcatccg atgccaaatc tcgccgctgt catgcccata acgccgcacc gtttcataca
    22441 cctggtcgtg cgcgccctgc tcgcataacg acgataattt atgatagaaa cccagtgcca
    22501 gactgcgcgc ttccggattg gcgaaatagt ggcgaccaat gcgggtgtat aaccctttca
    22561 tgccgttcag gatcaagccg taaataggat tgccggaggc aaatgccaga ccacgaaaga
    22621 tgttatagtc cagatcggcg aatgcatcgg catggtcggc cacttcgtgg gcagtggcca
    22681 gcacttcctg cgccttatcc gggtgttgac gcaatgcggt acgaataaag atagtagaaa
    22741 tattggtacg caccgacaac aaattgtcga tcagttgcgg aacgctttca tgatcaaggc
    22801 gggccagcgt ttcaaggata ttcagccctg acgtttccca aaaattatta acctttgtcg
    22861 gtttgccatg ctgaatggtc agccagccat ctcgcgccag ccgctgtaac acctcgcgta
    22921 atgtcgtgcg cgtcacgccg atcagttcgg agagttctcg ttctgccggt aagatcgtgc
    22981 caggaggaaa gcagttattc cagatacttt caataatata ctcttccgcg aaacccgcgg
    23041 ggctctgcgc cttaatgacc atagtgagat ttccattaca cagcaaaaca tagttgtact
    23101 catcatacca gacgggcgta acacctgata gcggacgcaa tgaagaaaaa ggggatcaag
    23161 gcaccatttc tgatatcgcc tgccaatatc gttaaggact tgcttgcatt cgtcgcgctc
    23221 gctactctct gtgtttaaac ataaaaacgc tatttcattt ttctaggtaa ggaaaaattt
    23281 catggagatc tcatggggtc gcgccatgtg gcgcaacttt ttaggccagt cgcccgactg
    23341 gtacaaactg gcactacttg tctttttaat tgttaaccca ttcattttct tagctaatcc
    23401 ctttgttgct ggttggctgc tggtggcaga gtttatcttc accctggcga tggcgttaaa
    23461 gtgttacccc ctgctgcccg gcgggttact ggccattgaa gccgttatca tcggcatgac
    23521 cagcgccgcc catgtacgtg aagaggttgc cgccaacctg gaagtcttgc tgctgctgat
    23581 gtttatggtg gcaggcatct actttatgaa gcagttattg ctgtttattt ttacccgtct
    23641 gttactcagt atccgctcga agatggttct gtcgctggcc ttttgcgtcg ccgccgcatt
    23701 cttgtcggct ttccttgacg cgcttaccgt cgttgcggtg gtgatcagcg tcgccgtcgg
    23761 tttttacggg atttaccatc gtgtggcctc atcgcgcggc gaagagaacg atatgctgga
    23821 cgacagccat atcgatccgc attacaaaac ggtgctggag caattccgcg gattcttgcg
    23881 tagtctgatg atgcatgcag gcgtggggac ggcgctgggc ggcgtcatga ccatggtcgg
    23941 ggagccgcaa aacctgatca tcgctaaagc tgctggctgg catttcggcg acttcttttt
    24001 gcggatgtcg cctgtcaccg tcccggtact ggtatgtgga ctgttaacct gtatgctggt
    24061 cgagaaaatg cgctggtttg gctatggcga aacgttgccc gaaaaagtcc gcgacgtctt
    24121 gcagcaattc gacgatcaaa gccgtaagaa gcgcacccgc caggataaaa ttaaactaat
    24181 agtccaggcg gttattggcg tctggctggt taccgccctc gccctccatc tcgcggaggt
    24241 gggactgatt ggtctgtcgg tcattattct ggccaccgcg ttaacgggtg tcaccgatga
    24301 acacgccatc ggcaaagcgt ttaccgagtc gctgccgttt actgcgctgt taaccgtttt
    24361 cttctctatt gtggcggtta ttatcgatca acatcttttc gcgccgatta ttcagttcgt
    24421 cttgcaagcc tctgaacacg cacagctaac gctgttctat ctctttaacg gcctgttgtc
    24481 ttccatctca gataacgtct ttgtcggcac catttatatc aacgaagcga aggcggcaat
    24541 ggaaaacggc gcaatcagct taaaacagtt tgagctgcta gctgtggcca tcaataccgg
    24601 tactaacctg ccatcggtag cgacgccaaa tggtcaggcg gcattcttat tcctgctgac
    24661 ctccgcgctg gcgccgttaa tccgtctctc ctatggccgt atggtctgga tggcgttacc
    24721 gtacactatc gtactgaccc tgatagggct actgtgcgtc gaattcactc ttgcgccggc
    24781 caccgaatgg atgactcagg caggatggtt agcaacgctt tcgtaacgtt tggccgggca
    24841 atacaccgcc cggctccgat ttttgcctga taattatcca attacacatt atttcatttc
    24901 ccgctagtgg cgcacgaatt gaattggttt acactgcggt ctctacgcat gttgcaggga
    24961 aattattatg ttgcgatttt taaaccagtg ctcacggggt cggggcgcat ggttactgat
    25021 ggcgtttacc gccctggcgc tggaaatggt ggcgctgtgg ttccagcacg tcatgttact
    25081 taaaccttgc gtgctatgta tttacgaacg ttgcgccctg tttggcgtga tgggcgcggg
    25141 tctggtcggc gcaatagcgc cgaaaacgcc gctgcgatac gtggcaatgg ttatctggat
    25201 ttacagcgcc tggcggggtc tacaactggc gtatgaacat acgatgattc agttgcatcc
    25261 ctcgccgttc atgacctgtg actttatggc gcgctttcca gactggttac cgttgggtaa
    25321 atggctaccg caggtgtttg tggcatccgg tgattgcgcc gagcgccagt ggtcgttttt
    25381 aacgctggag atgccgcaat ggctgttggg gatctttgcc gcttaccttg tggtagcgat
    25441 agctgtcgtc atagctcagg catttaagcc taaaaaacgc gacctgttcg gtcgttgata
    25501 cacacgctcc ttcgggagcg tttttttgcc cgaagcgttg tttgccagtg attaaaaggt
    25561 gtatattaaa tacatctttt aatcaccaca tcagggagat gtcttatgtc ccacttacgc
    25621 atcccggcaa actggaaagt taaacgctct accccctttt acaccaaaga gaatgttccg
    25681 gcggcactgc tctctcatca caacacagcg gcaggcgttt tcggacaact ctgcgtgatg
    25741 gaaggcaccg tgacctacta tggctttgcg aatgaaaccg cgacagaacc agaagtgaaa
    25801 gtggtgatta atgccgggca attcgccacc agtccgccgc aatactggca tcgggtagag
    25861 ctgagcgatg atgcgcggtt caacattcat ttttgggtag aggaagacca tcagggcgag
    25921 gaaatgtatc aacagaaaaa agcctgacat cggtaaacca gttaccactg ggcggcgtcc
    25981 cgcccagtag ccaggtgatt aatggcgcta attaaacgct agagtagttt aattttaacg
    26041 tggtatccct caagcccttt catcgtttct cgcggcgcga actctatttc ggaaacctct
    26101 tgcccggttt tcttccgtag ttcggcgacc tttttgctaa tgagtgccgc gatttcctct
    26161 tctgctttat gtgtcaactc ttcgctgttc attgatttcc tcctttgaac tcgcaaacgg
    26221 ctaagcgcaa taagacagtg tcgtcatgga cgcgctacta ttttaacgta caaaaaatta
    26281 taggctatct ttctgaggat tatcaggatg tttcgcttta gaagatgcaa aaaaccgcct
    26341 ggcacagacg gtgcatcagg cggttggtta atagcacaag acgctatcta cgaggatctt
    26401 caacctcatt ctgggtatcc gggtcgagag gatcgtctcc ctctggcgta tccggaatat
    26461 tttcaccagg aagcggctca tcctctggta atggatcgac taaatcagga cgttcagaca
    26521 taaagcctcc aacgaaccat agttattaaa gataccctac agcactactt ttggtttttc
    26581 tttggatttt ttccttcgtc ttcgggtgtc ttatcaggct tcctgggctg atcctttgaa
    26641 acgcgcaacg gttggttatt catggggtaa ctcctcagga taggcagcga tatactgctt
    26701 tgaaagtata gagtcgccgc catacgtgcg cgagcgcagc gacaaggcgc gtcagggaag
    26761 aatagaaggc agtgataacg ccaggtgacg gaatttgcac gcaattcctg atttcagggg
    26821 ccgcccagcg taaattaaag aattgtaaac aatcagccgt tttgccgaag acttattctg
    26881 cccacgacgg tttatttaaa atatgatcct gccagtcccg tacttcggat tctttaaccg
    26941 cgatatgacg gacagaaatt cgctcgccat gcatagcggc tttcgatcca gtctgcagcg
    27001 gatgccacgt cggcaagggc ttaccttccg ccaacaaacg gtaggcgcag gtcatcggca
    27061 accattcaaa gtctggcaag ttttcgcgag tgagtttgat acagtcgggt tcaaattcaa
    27121 aacggcgttc ataatgacgg cactggcacg ttttgatatt taattgcctg cacgccacgt
    27181 tggtgaagta gatttcatct gtatcttcat ccatcagctt atgcaggcag cattgaccgc
    27241 agccatcgca cagcgactcc cactcggcat cggtcatttc atccagggtt ttacgttgcc
    27301 agaaaggtgt atcgctcatt aaagtatccg ccattgcatt aaagctgcac cttataacca
    27361 gtctggcctg cagatgcaag ttttaccgcc gctgaaggcg gcaagcagat tttacagaac
    27421 gcgggtagac aacgtttcgc cattaaaacg aatgtccagc tcatcgccgc ttaataatgg
    27481 ccccacgcct gccggcgtgc cggttagcac cacgtccccg gctttgagcg taaaatagcg
    27541 gctcatatag gcgataaggg gcacaatagg atgaatcata tccgcggtcg acccttgctg
    27601 gcgaacctcg ccattaacgt taagtccgat aaccgtattt tgcggatcgc cgcagaaggc
    27661 cgcgacaggg atgaagcctg aaatcggaca tgcgttatcg aaacctttgg ctttttccca
    27721 aggctgtccg gcctttttca ttttcccttg aatatcgcgc agggttaaat caagcgccac
    27781 gccataaccg gctatcgctt tacgtacatg atcttcggtc gcctggcgga gcgttgcgcc
    27841 aatcagcacg gcaagctcaa cttcatgatg aacagcgccc atatccgccg gaatcgccag
    27901 cggctggcga atatcacaca atgcggtttc cggcttgata aaaagcacgg gttcttccgg
    27961 cgtcgcgctg cccatctcct tgatgtga
//
LOCUS       DAJVKX010000051        27807 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000051 DAJVKX010000000
VERSION     DAJVKX010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 27807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27807
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.051"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(379..2421)
                     /gene="dcp"
                     /locus_tag="OPY25_002252"
     CDS             complement(379..2421)
                     /gene="dcp"
                     /locus_tag="OPY25_002252"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HCS0927858.1"
                     /translation="MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEA
                     IVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTAAHTNDELQRLDEAFSAELAALS
                     NDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVL
                     NTESATLMSQFNQRLLAASKAGGLAVDDAHCLEGLSPEEMTVAAEAAREKGLEERWFI
                     PLLNTTQQPALATLRDRQTRENLFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLG
                     FPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQNVIDGEQGGYTVQAW
                     DWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHP
                     DVRVWEIFDSDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQK
                     PVDGQPALLLWDDVITLFHEFGHTLHGLFAVQRYATLSGTNTPRDFVEFPSQINEHWA
                     SHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELFGAALLDMRWHMLEES
                     VAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDG
                     YQWFVEQGGLTRENGQRFRDAILSRGNSTDLETLYSAWRGHEPHIDTILQYRGLDH"
     gene            2560..3305
                     /gene="ydfG"
                     /locus_tag="OPY25_002253"
                     /pseudo
     CDS             2560..3305
                     /gene="ydfG"
                     /locus_tag="OPY25_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460471.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
     gene            3435..4121
                     /locus_tag="OPY25_002254"
     CDS             3435..4121
                     /locus_tag="OPY25_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0927859.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIPPGTPLSEKEVSTR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISLSQVQNGCFVRQAIECAVVRRAA
                     AMITDNQCYQLAQNLHLQHIAIERKQIDDFFQLDDDFHQKLAQIADCQLAWDTIENIK
                     ATIDRVRYMSLDHVSPPEMLLRQHHDIFSALENRDGNAVESAMTQHLQEISESVQLIR
                     QENSGWFSEE"
     gene            4302..4505
                     /gene="ydfZ"
                     /locus_tag="OPY25_002255"
     CDS             4302..4505
                     /gene="ydfZ"
                     /locus_tag="OPY25_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HCS0927860.1"
                     /translation="MMTYDRNRNAITTGSRVMISGTGHTGIIKAIESEGLDAGQIRRG
                     KTVIVEGCEGKFAPVELIRLGMN"
     gene            complement(4572..6038)
                     /locus_tag="OPY25_002256"
     CDS             complement(4572..6038)
                     /locus_tag="OPY25_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCS0927861.1"
                     /translation="MQNRLLSAKATLPDYDRAALAARMVHLGFGAFHRAHQGVYTDIL
                     AAEQHSDWGYYEVNLIGGEQQIADLKQQDNLYTVAEMSADAWTARVVGVVKAALHVQV
                     DGLERVLAAMCEPQIAIVSLTITEKGYCHSPATGQLLLEHPMIAADLQNPHQPLTAPG
                     IIVEALARRKAAGLPAFTVMSCDNMPENGHVTRQVVTAYAREVDAELAIWIEQNVTFP
                     STMVDRIVPAVTPETLDKIEQLTGVRDPAGVACEPFRQWVIEDTFVAGRPQWENAGAT
                     LVADVVPFEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMDDDNYRLTAQALMLREQAP
                     TLKVQGVDLQRYADQLIARYRNPALRHHTWQIAMDGSQKLPQRMLDSVRWHLANHSDF
                     DLLALGVAGWMRYVGGVDEQGKAIDVSDPLLPVIQRAVANSEEGASRVKALLGMAEIF
                     GNDLPQAARFTQKVQEAYDSLLTYGAKASVAKYAERLK"
     gene            complement(6182..7561)
                     /locus_tag="OPY25_002257"
     CDS             complement(6182..7561)
                     /locus_tag="OPY25_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012210164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HCS0927862.1"
                     /translation="MTQIKHERSTQDLVRAAVSGWLGTALEFMDFQLYSLGAALVFHE
                     IFFPEQSAAMALILAMGTYGAGYIARIIGAFVFGKMGDRIGRKKVLFITITMMGICTT
                     LIGVLPTYAQIGIFAPVLLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSLVA
                     MGTNCGTLSATAIWAVMFFALEREQLIAWGWRIPFLASVVVMIFAIWLRMNLKESPVF
                     EKVSEGEKSPALTPASENTLGAMFTSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTL
                     LFNKSIPTDALMISSVIGFITIPLLGWLSDKYGRRLPYIILNISAIILAWPMLSIVVD
                     KTYSPGVIMAALIVIHNFAVLGLFALENITMAEIFGSRNRFTRMAISKEAGGLVAVGF
                     GPVLAGIFCNMTDSWLPILIMLVLYSCIGLISALLMPEVRDRDLSLPEDAAEATAAEK
                     LRHSATQTS"
     gene            complement(7615..8478)
                     /locus_tag="OPY25_002258"
     CDS             complement(7615..8478)
                     /locus_tag="OPY25_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HCS0927863.1"
                     /translation="MKSIVIEKPNTLTIETRALLQPASGEVRIKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGDNVNRDRIGERVSVDPVISCGHCYPCSVGKPNV
                     CTSLVVLGVHRDGGFSEYAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNPTE
                     QDVALIYGAGPMGLTTVQALKGVYQVKTVIVVDRIEESPAARIVLMGFSSDPCEIVQQ
                     GITGKELAIYSSRLNANKFPVVIDWLNKGLIDPDKLITHTFDYQHVTDAIELFEKDQR
                     QCCKVLLTFAK"
     gene            complement(8489..9703)
                     /gene="rspA"
                     /locus_tag="OPY25_002259"
     CDS             complement(8489..9703)
                     /gene="rspA"
                     /locus_tag="OPY25_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HCS0927864.1"
                     /translation="MKIVGAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLTDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHTIDDVLEDYARHKEQGFKAIRVQCGVPGMKTTYG
                     MAKGKGLAYEPATKGQWPEEQLWSTEKYLDFTPKLFDAVRNTFGFNEHLLHDMHHRLT
                     PIEAARFGKCIEDYRLFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTITHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEFMGYSEQMLEVFPHNWTFEGGYMHPGDKPGLGIEFNEKLAAKYPYDPAYLP
                     VARLEDGTLWNW"
     gene            complement(9825..10151)
                     /locus_tag="OPY25_002260"
     CDS             complement(9825..10151)
                     /locus_tag="OPY25_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HCS0927865.1"
                     /translation="MLKTTLLFFVTALCEIIGCFLPWLWIKRGASVWWLLPAAASLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALLWLRVVDGVRLTVYDWSGALIALCGMLIIV
                     VGWGRT"
     gene            10304..10645
                     /locus_tag="OPY25_002261"
     CDS             10304..10645
                     /locus_tag="OPY25_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HCS0927866.1"
                     /translation="MNNTLSKRLCLTAMLTLAAVVYTTSAFAETSKLVIESGDSAQSR
                     QEAAMEKEQWNDTRSLRQKVNTRAEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            10681..11241
                     /gene="speG"
                     /locus_tag="OPY25_002262"
     CDS             10681..11241
                     /gene="speG"
                     /locus_tag="OPY25_002262"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HCS0927867.1"
                     /translation="MTSDYKVRLRPLEREDLRFVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGENAGLVELVEINHVHRRAEFQIIISPEYQGKGLASR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFRVEGELIHEFFINGEYRNTI
                     RMCIFQQQYLDEHKTSSSTLLKPTAQ"
     gene            complement(11282..11992)
                     /locus_tag="OPY25_002263"
     CDS             complement(11282..11992)
                     /locus_tag="OPY25_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HCS0927868.1"
                     /translation="MKKPLLLTLLCMILAGCDNPKSPESFTPEMASFSNEFDFDPLRG
                     PVKDFSQTLMSENGEVAKQVTGTLSQEGCFDTLELHDLENNTGLALVLDANYYRDAQT
                     LEKKVQLQGKCQLAALPSAGVTWETDDNGFVVSATGKEMKVEYRYDSEGYPLGKTTIN
                     SQNTLSVTAKLSTDSRKKLDYTAVSRVDDRQVGNVTQSCEYDAYANPVDCRLVIVDES
                     VKPAVSHHYTIKNRIDYY"
     gene            12096..12405
                     /locus_tag="OPY25_002264"
                     /pseudo
     CDS             12096..12405
                     /locus_tag="OPY25_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
     gene            12559..15000
                     /locus_tag="OPY25_002265"
     CDS             12559..15000
                     /locus_tag="OPY25_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HCS0927869.1"
                     /translation="MMPGEKQQTGVSRRTLVKSAALGSLALAAGGVSLPFGMRTAAAA
                     VQQAMRNEEDKIVWGACSVNCGSRCALRLHVKDNEVWWVETDNTGDDVYGNHQVRACL
                     RGRSIRRRINHPDRLNYPMKRVGRRGEGKFERISWQEALDTISASLKKTVEIYGNEAV
                     YIHYSSGIVGGNITRSSPSASPVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDG
                     NSTSDIENSKLVVMFGNNPAETRMSGGGITWFLEQARERSNARMIVIDPRYTDTAAGR
                     EDEWIPIRPGTDAALVAGIAWVLINENLVDQPFLDNYCIGYDEKTLPADAPPNGHYKA
                     YILGQGEDGIAKTPQWASHITGIPADRIIKLAREIGSVKPAYICQGWGPQRQANGEQT
                     ARAIAMFPILTGNVGIHGGNGGARESTYTITIERLPVLENPVKTAISCFSWTDAIARG
                     PEMTALRDGVRGKDKLDVPIKFLWNYAGNTLINQHSDINKTHEILQDEAKCEMIVVID
                     NFMTSSAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATTPKFERKPIYWVLS
                     EIARRLGDDVYQRFTEGRTQAQWLQYLYAKMQARDPALPAYDELKKMGIYKRKDPNGH
                     FVAYKKFREDPQANPLKTPSGKIEIYSSKLAHIASTWELAEGDVISPLPIYTPTFEGW
                     DDPKRSTFPLQLFGFHYKSRTHSSYGNIDVLQAACRQEVWINPLDAQKRGIANGDKVR
                     VFNDRGEVRLPAKVTPRILPGVSAMGQGAWHNADMAGDKIDHGACINTLTTLRPSPLA
                     KGNPQHTNLVEIEKI"
     gene            15102..17537
                     /locus_tag="OPY25_002266"
     CDS             15102..17537
                     /locus_tag="OPY25_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HCS0927870.1"
                     /translation="MKITNPEALMAASISRRSLVKTSAIGSLALASSAFTLPFSRIAH
                     AAADLASGNMAEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGNDEYGNHQVRA
                     CLRGRSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTIGDNLKRILKDYGNE
                     AVHVLYGTGVDGGNITNSNVPYRLMNACGGYLSRYGSYSTAQISAAMSYMFGGNDGNS
                     PDDIANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGRED
                     EWLPIRPGTDGALAAAIGWVLITEDLIDKPFLDKYCIGYDETTLPASAPRNAHYKAYI
                     LGQGEDGIAKTPQWAAQITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTAR
                     AIAMLSVLTGNVGINGGNSGVREGTWDLGVEWFPMLENPVKTQISVFTWTDAIDHGAE
                     MTATRDGVRGKDKLDVPIKFLWCYASNTLINQHGDIAHTHEVLQDDSKCEMIVGIEHF
                     MTASAKYCDILLPDLMPTEQEDLISHESAGNMGYVILGQPATSPKFERKPIYWTLSEV
                     AKRLGPDVYQTFTEGRTQHEWVKYLHAKTKARNPEMPDYEEMKQTGIFKKKCPEEHYV
                     AFRSFREDPAANPLKTPSGKIEIYSERPATLANTWELKKDEIIHPLPAYTPGFDGWDD
                     PLRQRYPLQLTGFHYKARTHSSYGNIDVLQQACPQEIWINPIDAQARGIQHGDTVRVF
                     NQNGEMLIPAKVTPRILPGVTAIGQGAWLNADMFGDKVDRGGSINILTSHRPSPLAKG
                     NPSHSNLVQVEKA"
     gene            17548..18165
                     /gene="dmsB"
                     /locus_tag="OPY25_002267"
     CDS             17548..18165
                     /gene="dmsB"
                     /locus_tag="OPY25_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HCS0927871.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKRDDGFVVVNEEVCIGC
                     RYCHMACPYGAPQYNAAKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGELAAVAPLPRTHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            18167..19021
                     /locus_tag="OPY25_002268"
     CDS             18167..19021
                     /locus_tag="OPY25_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCS0927872.1"
                     /translation="MGSGWHEWPLVLFTVLGQCVAGALIVSGYGWLTTKDDVAKQRIV
                     RSMFFLWLVMGLGFLASIMHLGLPMRAFNSLNRVGASALSNEIAAGSVFFAVGGIWWL
                     VAVLGKMPPALGKVWLLVSMALGVAFIWAMTLVYQIDTVPTWYNGYTTLAFFLTAFLC
                     GPVFAALLLRIARVPFCSVTFASISGLALVVCVAVIVLQGLSLSAIHSSVQQASHLAP
                     DYGMLQVWRIVLLAAGLGCWLCPLIRRREPHTVGLLLGVVLVLAGEIIGRGLFYGLHM
                     TVGMAVAG"
     gene            19064..19678
                     /gene="dmsD"
                     /locus_tag="OPY25_002269"
     CDS             19064..19678
                     /gene="dmsD"
                     /locus_tag="OPY25_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HCS0927873.1"
                     /translation="MTTFLQRDDFAVTARVLGALFYYSPESHETAPLVQALLNDDWQA
                     QWPLDAEALAPVAAMFKTHSEESLPQAWQRLFIGPYALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMRENGIQFEMQQNEPEDHFGALLLLAAWLAENGRHHECEQLLAWHLFPWSP
                     RFLDVFIDHAGHPFYQALGQLARLTLAQWQAQLIIPVAVKPLFR"
     gene            19983..20693
                     /gene="osmY"
                     /locus_tag="OPY25_002270"
     CDS             19983..20693
                     /gene="osmY"
                     /locus_tag="OPY25_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter permease OsmY"
                     /protein_id="HCS0927874.1"
                     /translation="MHILTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQ
                     RHLMLVFTSMFFALLVGIPSGILLSRPAAKGFAEYVMQIFNVGNTLPPLAVLALAMVI
                     IGIGDTPAIVALFLASLLPIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNA
                     WPVMLSGIRIATAINVGTAPLAFLIGASSYGELIFPGIYLNDFPTLILGATATALFAL
                     ILDTLLAWFGRRLSPHTV"
     gene            20722..21624
                     /gene="osmX"
                     /locus_tag="OPY25_002271"
     CDS             20722..21624
                     /gene="osmX"
                     /locus_tag="OPY25_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein OsmX"
                     /protein_id="HCS0927875.1"
                     /translation="MRFKKHLLGWLATTLLFSSQTQAAPLVLATKSFTEQHILSAMTV
                     QYLQKKGFQVQPQTNIAAVISRNAMVNKQIDITWEYTGTSLIIFNRIDKRMSPQETYD
                     TVKRLDAKLGLVWLKPADMNNTYAFAMQRKRAESENITTISQMVAKIEQVRQNDPDHN
                     WMLGLDLEFAGRSDGMKPLQQAYQMQLDRPQIRQMDPGLVYNAVRDGLVDAGLVYTTD
                     GRVKGFDLKVLEDDKGFFPSYAVTPVVRKEVLEANPGLDDALNTLSGLLNNDVISTLN
                     AQVDIEHRTPQQVAHQFLQDKGLL"
     gene            21634..22281
                     /gene="osmW"
                     /locus_tag="OPY25_002272"
     CDS             21634..22281
                     /gene="osmW"
                     /locus_tag="OPY25_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter permease OsmW"
                     /protein_id="HCS0927876.1"
                     /translation="MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIV
                     RHKWLATPVLGAATLLLTIPSIALFGLMIPLFSLIGHGIGVLPAVTAVFLYSLLPIVR
                     NTHTALDSLPPGLREAGRGIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIA
                     AVIGAGGLGLLLLNGISGSDIRMLIAGALMICLLAIVLDWLLHRLQVVLAPKGIR"
     gene            22281..23429
                     /gene="osmV"
                     /locus_tag="OPY25_002273"
     CDS             22281..23429
                     /gene="osmV"
                     /locus_tag="OPY25_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter ATP-binding
                     protein OsmV"
                     /protein_id="HCS0927877.1"
                     /translation="MIKLENLTKQFVQKKGQPLKAVDNVNLNVPEGEMCVLLGPSGCG
                     KTTTLKMINRLIAPSSGNILINGENTNDMDTVTLRRNIGYVIQQIGLFPNMTIEENIT
                     VVPRMLGWDKARCKQRAEELMDMVALDARKFLHRYPKEMSGGQQQRIGVIRALAADPP
                     VLLMDEPFGAVDPINREVIQNQFLDMQRKLKKTVMLVSHDIDEALKLGDRIAVFRQGR
                     IVQCASPDELLAKPANEFVGSFVGQDRTLKRLLLVSAGDVTDQQPTITARPSMPLSEA
                     FGIMDDHDIRAITVIDNDGKPLGFVKRREARNASGICADITHPFRITGKAEDNLRIVL
                     SRLYESNTSWMPIVDEDGRYNGEISQDYIADYLSSGRTRRALNIHESS"
     gene            23565..24854
                     /gene="clcB"
                     /locus_tag="OPY25_002274"
     CDS             23565..24854
                     /gene="clcB"
                     /locus_tag="OPY25_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460450.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HCS0927878.1"
                     /translation="MHRLHAYPDLRAMFRRLLIATLIGILAALAVAAFRHAMQLLEWI
                     FLSNDTGSLVNAAEGLSPWRRLITPALGGLAAGLLLWGWQKMNQQRPHAPTDYMEALQ
                     TDGQFDVGASLVKSLASLLVVVSGSAIGREGAMILLAALAASSFARRFTPREEWKLWI
                     ASGAAAGMAGAYHAPLAGSLFIAEILFGTLMLASLGPVVVSAVVALLTTHVLNGSDSL
                     LYTVHLTVDLYAREYVMIVSTGLVAGLWGPLLMWLMTASHNSFLRLKLSPPWQLALGG
                     LIVGLLSLLTPTVWGNGYSVVQSFLLSPPLFSLIGGIFACKILAVLASSGSGAPGGVF
                     TPTLFVGLSIGMFLGRIWGFWLPGSDEIAILLGLAGMATLLAATTHAPIMSTLMICEM
                     TGEYQLLPGLLIACVVASVLSRTLRHDSIYRQHAAEH"
     gene            complement(24810..25505)
                     /gene="bioD"
                     /locus_tag="OPY25_002275"
     CDS             complement(24810..25505)
                     /gene="bioD"
                     /locus_tag="OPY25_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HCS0927879.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALSSGGKSVAGYKPVAKGS
                     KETPEGMRNKDALVLQSVSSLELPYEAINPIALSEEESSVAHSCPINYTLLSNGLASL
                     SDKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAVA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLS
                     MLGSVLAVDRIMA"
     gene            complement(25631..26851)
                     /locus_tag="OPY25_002276"
     CDS             complement(25631..26851)
                     /locus_tag="OPY25_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HCS0927880.1"
                     /translation="MVADSQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGSRGRPAVGLMVETEAWHYLSIRISRGEIFLALR
                     DLSSKLVVEECLALPLNEATPLLERIITHVDRFFTRHQQKLERLTSIAITLPGIIDTE
                     NGVVHRMPYYEDVKEMPLGDALERHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVNPYGKRCYCGNHGCLETIASVDSVLE
                     LTQLRLNQSISSMLHGQPLTVDSLCQAAMQGDLLAKDIISGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPAIADSIRQQALPAYSRNTVVESTQFTNQSTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            complement(26979..>27807)
                     /locus_tag="OPY25_002277"
     CDS             complement(26979..>27807)
                     /locus_tag="OPY25_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0927881.1"
                     /translation="ARLNISQPPLSQQIQILEQQVGARLLARTNRSVALTAAGRQFLA
                     DSRHILSLVNDAAARAERLHQGEAGEIRIGFTSSAPFIRAVSHTFSLFRQSYPGVHMQ
                     TREMNTREQIAPLNEGVLDIGLLRNTPLPDTLNREVILHEPLMAMIPREHRLAQKPVV
                     SLTELAEEPFVFFDPHVGTGLYDDILGLMRRYNLSPTITQEVGEAMTIIGLVAAGLGV
                     SILPASFKRVQMSEMRWVPLAEEDAVSEMWLVWPKHHEQSHAVQRFCQLLLLAARQD"
BASE COUNT         6739 a         7661 c         7055 g         6352 t
ORIGIN      
        1 caaaattacc ggaaccgccg cgatgttctg ccataatata atcctcatga tgatgttgcg
       61 ttttaaatat gatatgtctt ctcatatcat gtgatacagt tctaaatcta gtcgccctgt
      121 gcgcagtgtt aaattcattt ctgcattatt tacataatac caccacatgg cggaaaatat
      181 attttttgaa aacatcaaca gcgaagcggt aataaatctt tggcaatcaa gccaccacgg
      241 gaaaataagt agaaaaatcc gaatgcacgc cctcgttata ttcagacaac ttaaccccat
      301 aaatttaact ggctgtcatc agaagtgcag gattcatttt caggcggttg ttcgacagtg
      361 ccgaacaacc gtatcagctt agtgatcgag cccacgatat tgcaatatgg tgtcaatatg
      421 cggttcatgt ccacgccagg ctgaataaag cgtttctaaa tcagtactat tcccccggga
      481 aaggatagca tcacgaaaac gctgcccgtt ttcacgcgtc aggccgccct gctctacaaa
      541 ccattgataa ccgtcatccg ctaacatttg cgtccacagg taggcgtagt atcccgctgc
      601 gtagccgccg ccgaagatat gggcaaaata actgctgcga tagcggggcg gcactgccgg
      661 taaatcaaga tgctcggcgg ccagcgcctg ctgctcgaac tcagcgacag actgctctgc
      721 tacgctctcc tccagcatat gccagcgcat atccagcaat gcggcgccga acaattcagt
      781 catatcgtaa cctttattaa ataaactcgc cttgcgcatt ctttcctgta aatcagcagg
      841 cattttttca ccgctgtcga catgacgcgc gtagcgttcg aacacacgtg gatggctcgc
      901 ccaatgctca ttaatctggg agggaaactc gacaaagtcg cggggcgtat tggtacctga
      961 aagcgtggca tagcgctgaa cggcaaacaa accatgtaac gtatgaccaa actcatggaa
     1021 gagcgtaata acgtcgtccc aaagcagcaa tgcaggctgc ccatcaaccg gtttctgata
     1081 gttacataca ttgtatataa cgggccgggt ttcattgagt gtggattgct cgacaaaatt
     1141 ccccatccac gcgccgccgc ttttcgagtc ccgcgcgaag aagtcgccat aaaataacgc
     1201 catgccgaca ccatcggagt cgaaaatctc ccacacccga acatcagggt ggtacaccgg
     1261 aatgtcaaaa cgctcgacga aggtgatgcc gaatagctgg ttggcggtcc agaaaacccc
     1321 ctcttgcaac accgtattta aggcaaaata gggcttcagt tgcgcttcat ctaacgcata
     1381 tttttcccgc cgtacctgtt cggcatagaa catccagtcc caggcctgaa cggtgtagcc
     1441 gccctgctca ccatcaatga cgttctgaat ttccgcctgt tcattgagta cccgctgacg
     1501 cgctggcggc acaatgccac gcataaagct cagtgcggct tgcggcgttt tcgccatctg
     1561 atcggccatt ttccatgcgg cataattggg gaaacccagc agttttgcct gacagcggcg
     1621 aatctctacc agacgctgaa cgatagcgcg ggtatcgtgg gcatctcctt tttccgcccg
     1681 agtccatgac gctgcgaata aattttcgcg agtctggcga tcgcgcagcg tagcaagcgc
     1741 aggctgttgc gtcgtattaa ggagcggaat gaaccagcgc tcctccaggc ctttttcacg
     1801 cgccgcttca gcagcgacgg tcatttcttc cgggcttaat ccttccagac aatgcgcgtc
     1861 atctaccgcc agcccgcccg ctttacttgc cgccagcaga cgctgattaa actgactcat
     1921 taaggtcgcg gattcagtat tcaatacttt cagtcgcgct ttatcctctt cggcaagctg
     1981 cgcgcctgcc aacacaaaac gctgatggat aacatcgacc aaccgtagcg actcatcatc
     2041 cagccccagt gagtgacgct gttgccagac ggcatccacg cgagcgaata acgcgctatt
     2101 cagataaata tcgttggaga gcgccgccag ctcggcagaa aaggcctcat ccaaccgctg
     2161 gagttcatcg ttagtgtgcg cagccgtcat cgcgaaaaaa acgctggtga cgcgtgacag
     2221 aagcgccccg ctttgctcca gcgccagaag cgtattcgta aaatcagggg ccgccggatg
     2281 attgacgatg gcctcgattt ccacgcgttt ttgccgcacg ccctcatcaa aagcaggacg
     2341 ataatggcaa tctttgatcc gatcaaaacg cggtgcctga taaggcaaca tactctggtc
     2401 taacaaagga ttcgtcgaca tttttcactc ctgaaaatag gttgatcata agagtaagct
     2461 tccccctatg ctgaccgcaa ccgtgttaac caggattacc ctttcataaa cgccgcgtgc
     2521 tatggtaata caacacaaaa agcgttgagg aactgtgtga tgatcgtttt agtaactgga
     2581 gcaaccgcag ggtttggcga gtgcattgca cgccgttttg ttgagaatgg acataaagtc
     2641 attgccacgg gacgtcgtca tgaacgcctg caagcgttaa aagatgagct tggcgagaac
     2701 gtattgaccg cccaactgga cgtgcgcaac cgcgcggcca tcgaagagat gatggcctct
     2761 ctgcctgcgc agtggcgcga tattgatgtg ctggtcaata acgccggtct ggcgctgggt
     2821 cttgaaccgg cgcataaagc cagcgtagaa gactgggaaa ctatgatcga tactaataat
     2881 aaaggcttaa tttatatgac ccgcgccgtg ctgccaggaa tggtcgaacg taatcgcggt
     2941 catatcatta acatcggttc aaccgccggc agttggcctt atgctggtgg caacgtctat
     3001 ggcgcgacga aagcctttgt gcgccagttt agcctgaatt tgcgcacgga tttacacggc
     3061 acggcggttc gcgtgaccga cattgaaccg ggtctggttg gcggcaccga gttttccagc
     3121 gtccgtttca aaggcgacga tgagaaagcg ggtaaaacct acgaaaatac caccgcgctc
     3181 acgccagaag acattaccga agcggtatgg tgggtggcca cactccccgc gcattgaata
     3241 ttaataccgt tgaaatgatg cctgttaccc aatccttcgc agggctcagc gtccaccgta
     3301 gctaaggggt tatacccggt ctgcgggccg ggtaatccct ggcaaacgta tctgcaacca
     3361 gaaacatgat cggtatagac cgccacggaa aagtggtaga gtatccgggt caaccgccta
     3421 aaaagtaaga atgaatgacc gtcgaaacgc agcttaaccc tacacagcct gtcaaccagc
     3481 aaatttaccg tattcttcgg cgtgatatcg tgcattgtct tatcccgcct ggcacgccgc
     3541 tatcagaaaa agaggtctca acccgtttta acgtttcgcg tcagccggtg cgcgaggctt
     3601 ttataaagct ggcggaaaat gggttgattc agatccgccc tcagcgcggt agttatgtga
     3661 ataagatttc gctttctcag gtacagaatg gctgctttgt tcggcaggcg atcgaatgcg
     3721 cggtggtccg ccgtgcggcg gcgatgatca ccgacaacca gtgctatcaa ctggcgcaaa
     3781 acctgcacct gcaacatatt gccatcgagc gcaaacagat tgatgatttt ttccagcttg
     3841 atgacgattt ccaccaaaaa ctggcgcaga tcgccgattg ccagttagcg tgggatacca
     3901 ttgaaaatat caaagcgaca attgaccggg ttcgctatat gagtctggat catgtttctc
     3961 cgccggagat gttgctgcgc cagcaccatg atattttctc cgcgctggaa aatcgtgacg
     4021 gcaatgcggt tgagagcgca atgacccagc atttgcagga aattagcgaa tccgttcagc
     4081 ttatccgtca ggaaaacagc ggctggttta gcgaagagta acccccttta acgtcggggt
     4141 gagacgcctt ctccgctttc tcgccctgca cattcccgcc taaaaagccg tgagcttgat
     4201 caaaaacaaa aaaaatccgc aacgataagc gtatttatat gtcgcccgtc atgcggggaa
     4261 acctgcgggc tttggcagta agtttgaaag gagaaaacac catgatgaca tacgatcgta
     4321 accgtaacgc aatcaccacc ggtagccggg tcatgataag cggcacgggc cataccggga
     4381 ttatcaaagc cattgagagc gaaggtctgg atgcaggtca aattcgccgc ggcaaaacgg
     4441 tgattgtcga aggttgtgaa ggtaaattcg cgccagtcga actgattcgt cttggcatga
     4501 actgatacca ctggccgcta agaaccgctc cggccttccc ggtagcataa tgctaccggg
     4561 tctctgttac gctatttcaa gcgctcggca tatttcgcca cgctcgcttt cgcgccatat
     4621 gtcagtaaac tgtcataggc ttcttgcact ttttgcgtaa accgcgccgc ctgcggcaaa
     4681 tcgttgccga aaatttcagc cattcccagc agcgccttaa cacgactggc gccttcttca
     4741 ctgtttgcca cggcgcgctg aataaccggc aatagcggat cgctgacgtc gatcgcctta
     4801 ccctgctcat ccacgccgcc aacgtaacgc atccaccccg ccacgcccag cgccagcaaa
     4861 tcaaaatcgc tatgattagc aagatgccag cgaacggagt ccagcatacg ctgcggaagt
     4921 ttctggctgc catccatcgc aatctgccag gtatgatgac gcagcgccgg attacggtaa
     4981 cgcgcaatca actgatcggc ataacgctgt aaatctaccc cctggacttt cagcgttggc
     5041 gcctgctcgc gtaacattaa cgcctgcgcg gtcagacgat agttgtcgtc atccatacag
     5101 tcattaatat gctgatagcc ggcaagatac cccagataag ccaggaatga atgactgccg
     5161 ttaagcattc gcagtttcat ctcttcaaac ggaaccacgt cggcgaccaa cgtcgcgccc
     5221 gcgttttccc actgcggacg ccccgccaca aacgtatctt ctatcaccca ctgacgaaac
     5281 ggttcacagg caacgcccgc cggatcgcgc acgccggtca gttgttcgat tttatccagc
     5341 gtctccggcg tgaccgcagg gacaatccga tcaaccatgg ttgacggaaa tgtcacgttt
     5401 tgctcgatcc atatcgccag ttccgcatcc acctcccggg cgtaagccgt cacaacctga
     5461 cgcgtcacat gcccattttc cggcatgttg tcgcaggaca tcacggtaaa tgccggtaag
     5521 cctgcggctt tacgacgcgc taacgcttcg acaataatac ccggtgccgt tagcggttga
     5581 tgcggatttt gcaggtcggc ggcaatcatg ggatgttcca gcagaagttg acccgtggct
     5641 ggcgaatgac aatacccttt ctcggtaatg gtcagagaca caatcgctat ttgcggttcg
     5701 cacatcgccg ccagcacacg ttccagacca tcaacctgaa catgcaacgc cgctttgacg
     5761 acgcccacca cacgcgccgt ccaggcatcc gccgacatct ccgccacggt atagaggtta
     5821 tcctgctgct ttagatcggc aatctgctgt tcgccgccaa taagattaac ctcataatag
     5881 ccccagtcgc tatgctgctc cgcagccaga atatctgtat aaaccccctg atgcgcgcga
     5941 tgaaacgcgc caaaaccgag atggaccatc cgcgccgcca gcgccgcgcg atcgtaatca
     6001 ggaagcgtcg cctttgccga taaaagcctg ttttgcattt tataacctct atattctgaa
     6061 agcggaacag tcgcagagta acgcctgccc tggtgcattt ggatttacgc taattaaaca
     6121 aaagtgaccg gacagcatgg ccgaaaccgc attaacgttc cggccatacc gtcgacacga
     6181 tttaactcgt ctgggttgcg gagtggcgta acttctctgc cgctgtcgct tccgccgcat
     6241 cctcaggcaa actcaggtcg cgatctctga cctccggcat caacagcgca gaaatcagac
     6301 caatacacga gtagagcacc agcataatta agatgggcag ccaggaatcg gtcatgttac
     6361 aaaagatccc tgcgaggacg gggccaaagc caaccgccac caggcctcct gcctcttttg
     6421 aaatcgccat ccgggtgaag cgattacgcg atccgaaaat ttccgccatg gtgatgtttt
     6481 ccagcgcaaa taatcccagc acggcaaagt tatgaataac aatgagcgcc gccataatta
     6541 cgccagggct atacgtttta tctaccacaa tagacaacat cggccaggcg agaataatcg
     6601 cggagatatt caatattata tacggtagcc gacgaccgta tttatcggac aaccacccca
     6661 agagtgggat agtgataaaa ccaattacgg aacttatcat taacgcatcg gttgggatag
     6721 atttgttaaa taataacgtc tgaactaaat atccggcaag gaaagtttga ataagcccgg
     6781 aattccccgc ctgcccaaaa cgtaaaccgg tggccagcca gaaagatttg ctggtaaaca
     6841 tcgcgcccaa tgtattttct gacgcaggcg ttaacgctgg cgatttttcg ccttcgctta
     6901 ctttttcgaa taccggactt tctttcagat tcattcgcag ccagatcgcg aatatcataa
     6961 caacgacgct cgccaggaaa ggaatacgcc atccccaggc gatcagttgt tcgcgttcaa
     7021 gcgcaaagaa catcaccgcc cagatcgccg tcgcgctcaa cgtaccgcaa ttggtgccca
     7081 tcgcgaccag cgaggaaatg atgccacgct ttcctttcgg cgcatactcg gccagcatgg
     7141 tacccgcgcc ggaaatttcc gccccggcgc ccagcccctg tataattcgc aatgttacca
     7201 gtaatactgg cgcaaaaatg ccgatttgcg catacgtcgg cagtacgcca atcagcgtgg
     7261 tgcagatccc catcatggtg atagtaataa acaatacttt ttttcgtccg atgcggtcgc
     7321 ccattttacc aaaaacaaag gcgccgataa ttctggctat ataacctgca ccataggtgc
     7381 ccattgccag aataagcgcc atcgcggcag actgttccgg gaaaaatatc tcatggaaga
     7441 ccagagccgc gcctagtgaa tataactgaa aatccataaa ttcaagcgcg gtgcctaacc
     7501 agccagatac ggcagcgcgc actaaatcct gagtcgatcg ttcatgcttt atttgtgtca
     7561 tataggcaat ctctaagagg taagatgcgt accacttact cgcaagtatt tatattattt
     7621 cgcaaacgtg agtaagactt tgcagcattg acgctggtct ttctcgaaaa gctcaatcgc
     7681 gtcggtgaca tgttgataat caaatgtatg cgttatcagc ttatccggat caataagccc
     7741 tttattcagc cagtcaatca cgaccgggaa tttattggca ttaagacgcg atgaataaat
     7801 agccagctct tttccggtaa taccctgctg tacaatctca cacgggtcgc tggaaaatcc
     7861 catcaggaca atgcgtgccg caggcgattc ttcaatgcga tcaacgacta tgaccgtttt
     7921 aacctgataa acccccttca acgcctgtac ggtcgtcagt cccatcgggc ctgcgccata
     7981 gataagcgcc acgtcctgct cggtcggatt cacctgcccc gtcacatttg ccgcaatggt
     8041 aaacggctca accatgacgg catgatggtc tgcgatgttg tccggtatgc gatgagcatt
     8101 acgggccggc gccaccgcat actcgctgaa accgccgtca cgatgcacgc ccagcaccac
     8161 cagcgaggta cacacattgg gtttaccgac tgaacaaggg taacaatgcc cgcaactgat
     8221 caccggatcg acggataccc gttctcctat ccggtcgcga ttgacgttgt cgcctaccgc
     8281 gtcgatgaca ccgaaaaatt catggcctat gacacgggga tattttgcaa agggattatg
     8341 tccccgataa atatggctgt cggaaccgca gatacccgcc agtttcactt taatacgaac
     8401 ttcgccagat gctggctgca gaagcgcgcg cgtttcgatg gttaatgtat tcggtttttc
     8461 gattacgatg cttttcattt ttcgctcctt accagttcca cagtgtgccg tcttcaagac
     8521 gggccaccgg caaataggct ggatcgtacg gatatttcgc cgccagtttt tcattaaact
     8581 caatgcccag tcctggcttg tcgcccggat gcatatagcc gccctcgaac gtccagttat
     8641 gcgggaaaac ctccagcatc tgttcggagt agcccataaa ctcctgcacg ccaaagttag
     8701 gcacccacag gtcaaaatgt aatgccgcgg ccatacaaac cggcgacaga tcggacggcc
     8761 catgcgaacc ggtacgcacc tggtagagcg aggcaaaatc ggcaatgcgg cgcatcccgg
     8821 taataccacc ggcatgggta atcgtggtgc ggatatagtc aatcaattgc tcttcaatga
     8881 gctgtttgca atcccagata ctgttaaaga cttcgcctac ggcaatcggc gtaaccgtat
     8941 gctggcggat caggcggaag cactcctgat tttcagccgg cgtcgggtct tccatccaga
     9001 acaaacgata gtcttcaata catttgccaa agcgggcagc ctcaataggc gtcagtcggt
     9061 gatgcatatc gtgcagaaga tgttcattaa acccgaacgt attacgcacg gcgtcaaaca
     9121 gctttggcgt aaaatcgaga tacttttccg ttgaccacaa ttgttcttcc ggccactggc
     9181 cttttgtcgc gggctcatag gccagtccct tacctttcgc catgccgtag gtggttttca
     9241 tccccggaac gccgcactgc acgcggattg ctttgaaccc ttgctcttta tgacgcgcgt
     9301 agtcttccag cacatcgtcg atggtgtggc ctgtagtatg gcaatacacc atgacgcctt
     9361 cacgagaagc gccgccgagt aactgataca acggcatatt ggcggctttg gctttaatat
     9421 cccatagcgc catatcaact gcggaaatgg cggacatggt gacaggacca cggcgccagt
     9481 acgcaccttt gtagaagaac tgccagatat cttcgatgcg gtgagcatcc cgcccgatga
     9541 gttgtggaca cagatgatcg gtaaggtacg aggccaccga gagctcgcgt ccgttcaggg
     9601 tggcatcccc cagaccggtg atcccgtctt ccgtggttat ttttaaggtg acgaagttac
     9661 gccctggaca cgtaacaaaa acttcagccc ctacaatctt catttttatt ccttacatcg
     9721 cattatggga tgcaggaaat ttacccaact gagctactac catacaagta tatttatcta
     9781 aaaagcgctg ccagatcaca aaatgttctg gcagcgcggc aatgttacgt acgcccccat
     9841 ccaacgacga taatcagcat tccacacagc gcgatcagcg cgccgctcca gtcataaacc
     9901 gtgagccgga cgccatcgac aacacgtaac cacaggagcg cagtacagac atatacccca
     9961 ccgtaagccg cataaacccg cccactcgcc gccggatgca aggtcaaaag ccagacgaat
    10021 aacgcgagtg acgcggcagc gggcagaagc caccacacgc tggcgccgcg cttaatccat
    10081 agccagggaa gaaaacatcc aatgatttca cagagggcgg tgacaaagaa aagcagagtc
    10141 gtctttagca tgagattcat ttggttacga aatgataagt gataatacaa cagaatatcg
    10201 ttacggttat ccggccattc ttgtgtatat gccaggcata aggattggtg tagaatttac
    10261 aggtggttta ccgctttttc ccctctaatg aaaggatgtt gtgatgaaca atacgctgag
    10321 caaacgcctt tgcctgacgg caatgcttac gttggcggcc gttgtatata ctacttccgc
    10381 attcgctgaa accagtaaac tggtgattga atcgggagat agcgcacaaa gtcgtcagga
    10441 agcggcgatg gaaaaggaac aatggaacga cactcgcagt ctgcgtcaga aagtgaatac
    10501 ccgcgcagaa aaagagtggg acaaagccga tgccgccttt gataaccgcg ataaatgcga
    10561 gcaaagcgcc aacatcaacg cctattggga acccaatact ctgcggtgtc tggatcgtcg
    10621 tacaggtcgc gttattacgc cctgatgcag gataactaaa aggaagtgta aggatacagt
    10681 atgacaagtg actacaaggt cagactgcgc ccgcttgagc gtgaagattt acgatttgtc
    10741 caccagcttg ataataatgc cagcgttatg cgttactggt ttgaagagcc gtatgaggct
    10801 tttgtcgaac tgtcggatct ctacgacaaa cacatccacg accaaagcga acggcgcttt
    10861 gtcgtcgaat gcgacggtga aaacgccgga ctggtagaac tggtggaaat taaccatgtg
    10921 catcggcggg cggaatttca gattattatt tcgccggagt accagggaaa aggcctggcg
    10981 tcacgcgcgg ccaaactggc gatggattac ggatttaccg tactcaatct ctataaattg
    11041 tatttgatcg tcgataaaga gaatgaaaaa gcgattcaca tctaccgtaa actcgggttt
    11101 agagtagaag gcgagctgat tcatgagttc ttcattaacg gcgaataccg taacaccatc
    11161 cgcatgtgta tcttccagca gcagtatctg gatgaacata aaacgtccag ttctacgctc
    11221 ctgaaaccca ccgcgcagta agcgcggcgc ggtagtcacg gagagtcgca ccgcgcccgg
    11281 tttagtagta atcgatacga tttttaatgg tgtaatggtg ggacactgcc ggcttaacgc
    11341 tctcatcgac gataacaagc cggcagtcaa cagggttcgc gtacgcatca tattcgcagc
    11401 tctgtgtgac gttgccgacc tgtcgatcat ccacccggct gactgccgta taatccagct
    11461 ttttacggga gtccgtggag agttttgccg tcacagagag cgtattctgc gagtttatgg
    11521 ttgtcttacc taacggataa ccttcgctat catagcggta ctcgaccttc atctctttgc
    11581 ccgtcgccga taccacaaaa ccgttgtcgt ccgtttccca agtcacgccc gccgaaggca
    11641 acgccgccag ctggcacttc ccctgtaact gcaccttttt ttccagcgtc tgagcatccc
    11701 ggtaataatt agcatccagc acgagcgcca gccccgtatt attctccaga tcgtgtaact
    11761 caagcgtatc aaaacagcct tcctgtgaaa gcgtaccggt gacctgcttc gccacttcgc
    11821 cattctcact catcaacgtc tggctgaaat cctttaccgg accacgtaat ggatcaaaat
    11881 caaattcgtt cgaaaaactg gccatttccg gcgtaaaaga ctcgggggat ttcgggttat
    11941 cacaacctgc cagtatcatg cacaataacg tcagtaaaag gggtttcttc acgcgtgtca
    12001 ccaggatgaa aagatattta tcatcatatt agcaaataca gttatttaca cgaaaaatgc
    12061 taagcttaga acatcgtcat taatcacagg agttcatgat gaaaatcgca actgcaatag
    12121 ccgctctggc gttagtcagc gccccctcgc tggtgatggc ggcaccggga tcgtgcgaga
    12181 gagtaaaaag cgatatcgaa caacgtatca tcaataacgg cgtgccggcg gataatttta
    12241 cgctcactat cgttcctata cgaccaggcc gatcagccgg actcacaggt ggtgggccat
    12301 tgcgcgaacg acacgcataa aattctttat acccgcacca gcagcggcaa tgcgccagcc
    12361 aatacctctc ccgctcagga cggttcatcc gccgaaccac aataacctcc tcctgccctc
    12421 cgggtccgga gggtaacgct ctttgacatg gattaataat ccttactccc aaaggggtaa
    12481 actcattaca tcattagcat gttaataatt tcgctatagt cattaatata tagcgaaacg
    12541 ataacgacaa tggagtgagt gatgcccgga gaaaagcagc aaacaggcgt tagccgcagg
    12601 acgttagtga aatcagcggc gcttggctca ctggcgctgg ctgccggagg cgtatcttta
    12661 ccgtttggga tgcgtaccgc ggccgcggcg gtgcagcagg ctatgcgcaa cgaagaagat
    12721 aaaatcgtct ggggcgcctg ttcggtcaac tgcggcagtc gctgcgccct gcgtctgcat
    12781 gtaaaagata atgaagtctg gtgggttgaa actgataaca ctggcgacga tgtctacggc
    12841 aatcatcagg ttcgcgcctg tctgcggggc cgttcaatcc gtcggcgcat taaccatccg
    12901 gatcgcctta actatcccat gaaacgcgtt ggccgccgcg gcgaaggcaa atttgaacgc
    12961 attagctggc aggaagcgct ggacaccatt agcgccagcc tgaaaaagac cgtagagatc
    13021 tacggcaatg aagccgttta tatccactat tcatccggca tcgtaggcgg caacataacc
    13081 cgctcgtcgc cttccgcctc gccggtgaag cgtttgatga actgctacgg cggttcgttg
    13141 aatcaatacg gctcatacag taccgcgcaa atttcttgcg ccatgcccta cacctatgga
    13201 tccaacgacg gcaacagcac atctgatatc gaaaacagta aactggtggt catgttcggc
    13261 aataatccgg ctgaaacacg catgagcggc ggcggcatta cctggtttct ggagcaagcg
    13321 cgtgaacgct caaatgcgcg catgatcgtg atagatccgc gctataccga taccgctgcc
    13381 ggacgtgaag acgagtggat acctattcgc cccggcaccg acgccgcgct ggtggcggga
    13441 attgcctggg tattgattaa cgaaaatctc gttgaccagc cttttctcga caactattgc
    13501 atcggctacg atgaaaagac ccttccggct gacgcccccc ccaatggcca ttataaggct
    13561 tatattttgg gccagggcga ggacggtatc gccaaaacgc cgcagtgggc gtcacacatt
    13621 accggcatcc ccgccgatcg gattatcaaa ctggcgcgcg agataggtag cgtcaagccg
    13681 gcctacatct gtcagggttg gggcccgcag cgtcaggcga acggcgaaca aaccgctcgc
    13741 gccatcgcca tgtttccgat tctgaccggc aacgtcggca ttcatggcgg taatggcggc
    13801 gcacgcgaat ccacttacac cattaccatt gaacgtctgc cggtcctgga gaatcccgtt
    13861 aaaaccgcca tctcctgctt tagctggacg gacgccattg cgcgcggccc ggaaatgacc
    13921 gccctgcgcg acggcgtacg cggcaaagat aagctggatg tcccgatcaa atttctatgg
    13981 aactacgctg gcaacaccct gattaatcag cattcggata ttaataaaac ccatgaaatt
    14041 cttcaggatg aagcaaaatg cgaaatgatt gtggtcatcg acaattttat gacctcttcc
    14101 gcgaagtacg ccgatatttt actgccggat ctcatgaccg tcgaacagga agatatcatc
    14161 cccaatgatt acgccggcaa tatgggatat ctgattttta tccaaccggc gacgacgcct
    14221 aagtttgaac gcaagcccat ctactgggta ctcagcgaaa tcgccagacg cctcggtgac
    14281 gatgtgtatc agcggtttac cgaaggccgt acccaggcgc aatggctgca atatctgtac
    14341 gccaaaatgc aggcaagaga tccggcattg cccgcgtatg acgagctaaa aaaaatgggc
    14401 atctataaac gcaaagatcc caacggccac tttgtcgcct ataaaaaatt tcgtgaagat
    14461 ccgcaggcca atccgttaaa aacgccgtcc ggtaaaatcg aaatctactc aagcaaactc
    14521 gctcacatcg ccagtacctg ggagctggcg gaaggcgacg tgataagccc actgccgatt
    14581 tataccccta cttttgaagg atgggacgat ccgaagcgga gcaccttccc gctacagctg
    14641 tttggctttc actataaatc ccgtacccat tcaagctacg gcaatattga tgttctgcag
    14701 gccgcctgtc gccaggaggt gtggataaat ccgcttgatg cgcaaaaacg tggtatcgcg
    14761 aatggcgata aggttcgcgt ctttaacgat cgtggagaag tgcgtctacc cgccaaggtc
    14821 acgccgcgta ttctgccggg cgtcagcgcg atgggtcagg gcgcatggca taatgcggat
    14881 atggctggcg ataaaattga ccacggcgcc tgcatcaata cgctcacgac gctacgtcct
    14941 tcccccctgg caaaagggaa tcctcaacat acaaatctgg tggaaatcga aaaaatctaa
    15001 gccgcctgct ccggggcgtt tttacgcgcc cggagctccc cgttttgcga acacaacgac
    15061 atttaaaact cttttttgga tgagcatagt gaggagctgt tatgaaaatc accaaccctg
    15121 aggcattaat ggcggccagt atcagccgac gaagcctggt gaaaacctcc gctatcggta
    15181 gccttgcgct tgccagtagc gctttcaccc ttccgttctc ccgcatcgcc cacgccgcag
    15241 cagacctcgc atctggcaat atggcagaaa aagcggtctg gagttcatgt accgttaact
    15301 gcggcagccg ctgcctgctg cgcctgcacg taaaagatga caccgtatat tgggttgaat
    15361 cagataccac gggcaacgat gaatatggca accatcaggt acgcgcctgc ctgcgcggtc
    15421 gttctattcg tcgccggatg aatcatcccg atcgcctgaa atatccgatg aaacgcgttg
    15481 gtaaacgagg agaaggcaaa ttcgaacgta tcagttggga tgaagcgttg gataccatcg
    15541 gcgataacct taaacgcatc ctcaaggact acggcaacga agcggtacat gtcctttacg
    15601 gtaccggcgt ggacggcggc aatattacca attctaacgt accgtatcgc ctgatgaacg
    15661 cctgcggcgg ctatctcagc cgttacggta gctacagcac cgcccaaatc agcgcggcca
    15721 tgagctatat gttcggcggc aacgacggca acagtccgga tgatatcgcc aatacaaaac
    15781 tggtggtgat gtttggcaat aaccccgcgg aaacacgtat gagcggcggc ggcgtgacat
    15841 actatgtcga acaggcgcgc gaacgctcca acgcccggat gatcgtcatt gacccgcgtt
    15901 ataacgacac tgctgccggc cgcgaagacg agtggctgcc gattcgccca ggtaccgatg
    15961 gcgcgctggc ggcggcaatc ggctgggtgc tgattaccga agatcttatt gataaaccgt
    16021 ttctggataa atactgcatc ggctacgacg aaaccactct gcccgcctcg gccccgcgta
    16081 acgcgcacta taaagcctat attttgggtc agggcgaaga cggtattgct aaaacgccgc
    16141 aatgggccgc gcagattacc agtattccgg cggaaaaaat cattcaactg gcgcgggaaa
    16201 tcggctcggc gaaaccggct tacatttgcc agggctgggg accgcaacgc cactctaacg
    16261 gggagcagac cgcacgcgca atcgccatgt tgtctgtact caccggtaac gtcggcataa
    16321 atggcggtaa ttccggcgtg cgcgaaggca cctgggatct gggcgtcgaa tggtttccta
    16381 tgctggagaa cccggtaaaa acccagattt cggtctttac ctggaccgac gctatcgatc
    16441 atggcgcgga aatgaccgcc acacgcgacg gcgtgcgggg aaaagacaag ctcgacgtgc
    16501 cgatcaaatt tttgtggtgc tacgccagta atacgctgat caatcagcat ggcgatatcg
    16561 cccacaccca cgaggtgctt caggacgaca gtaaatgtga aatgatcgtc ggcatcgagc
    16621 actttatgac cgcgtcggca aaatattgcg acattctgct gcctgattta atgccgaccg
    16681 agcaggaaga tctgatttcc cacgaatccg caggcaatat gggctatgtc attcttggtc
    16741 agcccgccac ctcgccgaaa tttgaaagaa agcccattta ctggacgctc agtgaagtgg
    16801 ctaaacggct tggtccggac gtataccaga ccttcacaga aggccgcacg cagcatgagt
    16861 gggtcaaata cctgcacgca aaaaccaaag cgcgtaaccc ggaaatgccg gattacgaag
    16921 agatgaaaca gacagggatt ttcaagaaaa aatgcccgga ggagcactac gtcgctttcc
    16981 gctcattccg cgaagaccct gccgccaacc cactgaaaac gccgtccggt aaaatcgaaa
    17041 tctattccga gcgtccggca accctcgcca acacgtggga gctgaagaaa gatgagatta
    17101 tccatccttt acccgcctat acgccaggct ttgacggttg ggacgatccg cttcgtcagc
    17161 gctacccgct acagctaacc ggcttccact ataaagcgcg tacccactcc agctacggca
    17221 atatcgacgt cctgcaacag gcgtgtccgc aggagatctg gatcaacccg attgatgcgc
    17281 aagcgcgcgg cattcagcac ggcgacaccg tgcgggtctt taaccagaat ggagagatgc
    17341 tcattccggc aaaagtcacg ccgcgcatat tgcctggcgt caccgctatc ggccagggcg
    17401 cctggttaaa tgccgacatg tttggcgaca aagtcgatcg cggcggctcc attaacattc
    17461 tgacgtcgca ccggccttcc ccactggcga aaggtaatcc gtcacacagt aatcttgttc
    17521 aggttgaaaa ggcgtaagga gtaaccgatg acaacccagt atggattttt tattgattcc
    17581 agccgttgca ccggttgcaa aacctgcgaa ctggcctgca aggactacaa agatctcact
    17641 cccgacgtca gcttccgccg catttatgag tatgcgggcg gtgactggca ggaagataac
    17701 ggcgtctggc accagaacgt ctttgcctac tatctctcca tctcctgtaa ccactgcgaa
    17761 gacccggcct gtaccaaagt ctgcccgagc ggcgcgatgc acaagcgcga tgacggtttt
    17821 gtggtggtga atgaagaggt ctgtatcggc tgccgctact gccacatggc ctgcccgtac
    17881 ggcgcgccgc agtacaacgc ggccaaaggt catatgacca agtgcgacgg ctgttatgac
    17941 cgggtggcgg aaggcaagaa accgatttgc gtggaatcct gcccgctgcg ggcgctggat
    18001 ttcggcccga tagacgaact gcgcaaaaaa cacggtgagc tggctgccgt cgcgccgttg
    18061 ccgcgcacgc atttcacgaa gccgaatatt gtgattaaac ccaacgccaa cagccgcccg
    18121 accggggaca ccaccggtta tctggccaat ccgaaggagg tataagatgg gaagtggatg
    18181 gcatgaatgg ccgctggtcc tgtttacggt gctgggtcaa tgtgtggccg gggcgctgat
    18241 cgtgagtgga tatggctggt taaccaccaa agacgatgtg gcaaaacaac gcatcgtgcg
    18301 cagcatgttt tttctgtggc tggtgatggg actgggattc ctcgcgtcga ttatgcatct
    18361 cggcttgccg atgcgcgcgt ttaactcgct taaccgcgta ggcgcttccg cactgagtaa
    18421 tgaaatcgcc gcaggatcgg tgttctttgc cgtaggcggc atctggtggc tggtggcggt
    18481 actcggtaaa atgcccccgg cgctgggtaa agtgtggctg ctggtcagta tggcgctcgg
    18541 cgttgcattc atctgggcaa tgacgctcgt ttatcagata gataccgtgc caacctggta
    18601 taatggctac accacgctgg cctttttcct cacggcattc ctgtgcggtc cggtgtttgc
    18661 ggcgctactg ctacgcatcg cgcgcgtccc attttgcagc gtgacgtttg ccagtattag
    18721 cggcctggcg ttggtggtgt gcgtggcggt catcgtacta cagggactgt ccctctcagc
    18781 cattcacagt tccgtgcaac aggccagcca tctcgcaccg gattacggta tgctacaggt
    18841 ctggcgcatt gtcttgcttg ctgccggatt aggttgctgg ctatgtccac taatccgtcg
    18901 ccgcgaaccg cataccgttg gtttgctgct cggtgtcgta ctggtgctgg cgggcgaaat
    18961 tattggccgc ggactttttt atggcctgca tatgaccgta ggtatggccg tcgcaggtta
    19021 atttatgcgt gcggggcgac ccgcaccttt cgggattgtt tgaatgacca cttttttaca
    19081 acgtgatgat tttgcagtaa cggcgcgtgt tcttggcgcg ttgttttatt attcgccgga
    19141 aagccacgaa accgctcctc tggtccaggc gctattaaac gacgactggc aggcgcagtg
    19201 gccgcttgat gccgaggcgc ttgcacctgt ggcggctatg tttaagaccc acagcgaaga
    19261 gtcgttgcca caagcctggc agcgcctgtt tatcggccct tacgctctgc cgtctccgcc
    19321 gtggggttcc gtctggctgg atcgtgagag cgtattattt ggcgattcta cgttggcgct
    19381 acgtcagtgg atgcgcgaaa acgggattca gtttgaaatg cagcaaaacg agccagaaga
    19441 tcattttggg gcgctgttgt tgctggcggc ctggcttgcc gagaatggcc gtcatcatga
    19501 atgcgaacaa ctcctggcct ggcatctgtt tccgtggtcg ccccgctttc tggacgtatt
    19561 tatcgatcat gccgggcatc cgttttatca ggcgttgggg caactggcgc gtctgactct
    19621 ggcgcaatgg caagctcaac tcattattcc cgtcgctgta aaaccgttat tccgttaatc
    19681 cccacaaaag gcaggatttt acctgccttt tctcccattg tggcctattt ttatctacaa
    19741 aaagtgacaa cgtcacacct cgcttctatt tttaagataa ttctttatcg tgaatgttca
    19801 cgctaagccg cataagggca aaacataatt gttaatagat gtttaacagt gttaaacatc
    19861 acgctccgct ggaatccttc ccaacctgtt gctatagctc aaagcaccct gccggaacat
    19921 ggcataacaa cacgcgactc ttaacgtcgc cataacacat gcaaacaggg agacacaccg
    19981 caatgcacat cctcacccta aaacgcgtac ttgggttcac tatcgtcatt ctgctgttac
    20041 tggcgctgtt tatctgggga atcggtctgg agacgctgaa agcgcgtcag gtcgatctgc
    20101 tgtatctcgg acaacggcat ttgatgctgg tctttacgtc catgtttttt gctttactgg
    20161 tcggtatccc gagcgggatt ttactcagcc gacctgcggc aaaaggattt gctgaatatg
    20221 tcatgcaaat ctttaatgtt ggtaatacct tgccgccact ggccgtcctg gccttagcga
    20281 tggtgattat cgggatcggc gatacgcccg ccattgtcgc gctatttctg gcttctcttc
    20341 tgcctatcgt ccgcaatacc tatgcaggcc tctgttccgt tcccgcctca ctgattgaag
    20401 cggcgaacgg gattgggatg acaaaatggc agcggcttcg ccaggtagag ctacctaatg
    20461 cgtggccagt gatgctgtcc ggtattcgca tcgcgaccgc catcaatgtc ggcaccgcgc
    20521 cgctggcctt tctgatcggc gccagcagct acggcgagct gatttttccg gggatttatc
    20581 tcaacgattt tccgacgttg attctcggcg caacggccac ggcgttattc gcgctgattc
    20641 ttgacactct gcttgcctgg tttgggcgac gccttagtcc tcataccgtc tgaacgcata
    20701 aataacaata aggagcgtta aatgagattc aaaaaacacc tgttgggatg gcttgccaca
    20761 acgctgttgt tcagtagcca gacgcaggcc gcgccgctgg ttctcgccac caaaagcttt
    20821 accgagcagc atattctttc cgctatgacc gttcagtatt tgcagaagaa aggctttcag
    20881 gttcagccgc aaaccaatat cgccgcggtg atttcacgta atgcgatggt gaataaacaa
    20941 attgatatta cctgggaata taccggtaca tcgctgatta ttttcaaccg tatcgataag
    21001 cgcatgagtc cacaggaaac ctacgacacg gtaaaacgcc tggatgcgaa gctgggcctg
    21061 gtatggctca aaccggctga catgaacaat acttacgcgt tcgcgatgca gcgtaaacgc
    21121 gccgagtcgg aaaatatcac caccatctcg caaatggtgg caaaaatcga acaagtccgg
    21181 cagaacgatc ctgaccacaa ctggatgctc ggcctcgatc tggaatttgc cgggcgcagc
    21241 gacgggatga agccccttca gcaagcctac cagatgcagc tcgatcgccc gcaaatacga
    21301 cagatggacc cagggctggt ctataacgcc gttcgggatg gactggttga cgccgggctg
    21361 gtctatacca ccgacggacg ggtgaaaggg tttgatctga aagtgttgga agatgataaa
    21421 ggcttctttc caagttacgc tgtcacgccc gtggtgcgta aagaggtgct ggaagccaat
    21481 cctggtcttg atgacgcctt aaacaccctt tccggcctgc tcaataacga tgtgatatcg
    21541 accctaaacg cccaggtcga tatcgagcat cgcacgccgc aacaggtagc ccatcaattt
    21601 ttgcaggaca aaggtctgct gtaaggagcg cctatggata cgatacatta tatgctggat
    21661 aacgcaggct atctcgccag ccttaccttt cagcatctct ggctagtcgc gctggccgtc
    21721 ggtctggcga ttatcatcgg cgtaccgtta ggcgttttga ttgtacgcca caaatggctg
    21781 gcaacgccgg tattgggcgc cgccacgcta cttcttacca ttccgtctat cgcgctgttt
    21841 ggattaatga tcccgctctt ttcgctgatc gggcatggta ttggcgttct gcccgctgtg
    21901 acggccgttt ttctctactc tttactgccg attgtccgga atacccatac tgcgcttgat
    21961 agtttgccgc ccggtctgcg tgaagcggga cgcggcatcg gtatgacttt ctggcaacgg
    22021 ctgcgctggg tcgaaatccc aatggcccta ccggttattt tcgggggtat ccgcaccgcg
    22081 gtagtgatga atatcggcgt gatggcgatt gccgcggtga tcggcgccgg cggtctgggg
    22141 ctgctactgt taaacggcat tagcggcagc gatattcgca tgttaattgc cggcgcgctg
    22201 atgatctgtc tactggcaat tgtacttgac tggctgttgc atcgtctgca agtcgtactg
    22261 gcacctaagg ggatacgata atgataaaac tggaaaatct caccaaacaa tttgtacaga
    22321 aaaagggtca gccgctaaaa gccgtcgaca acgtcaacct gaacgtgccg gaaggcgaaa
    22381 tgtgcgtctt actcggtccc tccggctgcg gcaaaaccac cacgttaaag atgatcaacc
    22441 ggctgatcgc gcccagcagc ggtaatattc ttatcaacgg cgagaatacc aacgatatgg
    22501 atacggtaac gctacgccgc aatattgggt atgttatcca acagatcggc ctgtttccta
    22561 atatgacgat tgaagaaaat attaccgttg tgccgcgcat gttgggttgg gacaaagcgc
    22621 gctgcaagca acgcgccgaa gagttgatgg acatggtggc gctggatgcc agaaaatttc
    22681 tgcatcgcta tccaaaggag atgtccgggg gacagcaaca gcgtattggc gtgatccgcg
    22741 ctctggccgc cgatccgccg gtactgctga tggatgagcc cttcggcgcg gtggacccca
    22801 ttaaccgcga agtgatccag aaccagtttc tggatatgca gcgtaagcta aaaaagaccg
    22861 tgatgctggt cagccatgat atcgacgaag cgctaaaact cggcgaccgt atcgccgtgt
    22921 tccgtcaggg gcgaattgta cagtgcgcca gtcctgatga actgctggcc aagccggcta
    22981 acgagtttgt cgggtcgttt gtcggtcagg acagaacgtt aaagcgtttg ctactggtct
    23041 ccgcaggcga tgtgaccgac caacagccaa ccattaccgc gcggccttcc atgccgttaa
    23101 gcgaggcgtt cggcattatg gatgatcacg atattcgcgc cattaccgtc attgacaacg
    23161 acggtaagcc actgggattt gtgaagcgcc gggaggcgcg gaacgccagc ggaatctgcg
    23221 ccgatatcac ccatcctttc cgtattacgg gcaaagcgga agataatctg cgtattgtgc
    23281 tgtccagatt gtacgaaagt aataccagct ggatgccgat cgttgatgaa gacggacgct
    23341 ataacggtga aatctctcag gattacatcg ccgattatct cagctcaggc cgcactcgtc
    23401 gggcgctaaa tattcacgaa agcagctaac gttgccgccg gatcgcctct cgctatccgg
    23461 cagtatcatt attgtacgca atattatatc gcacatagtg cttttgcgtc tgacgccatt
    23521 tccccgcaga ataggctatc ctgaaactcc ctgtttaccc gctcatgcat cgtttacacg
    23581 cttacccgga tctgcgcgcg atgtttcgtc gcctgctgat cgctacgctc atcggtattc
    23641 tcgcggcgct ggctgtcgcc gccttccgtc atgcgatgca attgctggag tggattttcc
    23701 tgagtaatga caccggcagt ctggtgaatg cggctgaggg gctttcgccc tggcgacggc
    23761 tgattacgcc ggcgcttggc ggcctggccg ctggtctgtt gctgtggggg tggcaaaaaa
    23821 tgaaccaaca gcgcccccat gcgcccactg actatatgga agcattgcaa accgacgggc
    23881 aatttgacgt tggcgccagt ctggtgaaat cgctggcctc gctgctggtc gtggtcagcg
    23941 gcagcgcaat tggtcgcgaa ggcgcaatga tcctcctcgc cgcgctggcg gcgtccagct
    24001 ttgcccgacg cttcacgccg cgtgaggaat ggaaattatg gatcgccagc ggcgccgctg
    24061 cgggcatggc gggcgcttac catgcgccgc tggcgggcag cctgtttatc gcggagatcc
    24121 tgttcggtac cttaatgctg gcttccctcg gcccggttgt cgtttccgcc gtcgtcgccc
    24181 tgctaaccac ccatgtatta aacggtagcg attcactact ctataccgta catctgaccg
    24241 ttgatctcta cgcgcgggag tacgtcatga tagtcagtac cggtctggtc gccggtctgt
    24301 ggggtccgtt gctgatgtgg ctgatgacgg ccagccataa tagtttctta cgcttaaaac
    24361 tgtccccgcc ctggcaactg gcgttgggcg ggcttattgt cggattactg tcgttactca
    24421 cgcccacggt atggggaaac ggctatagcg tcgtacaatc atttttgctc tccccgccgc
    24481 tattctcgct gattggcgga atttttgcgt gcaaaatcct ggcggtgctc gccagcagcg
    24541 ggtctggcgc gccgggcggc gtctttacgc caacattatt tgtcggatta tccattggaa
    24601 tgtttctggg tcggatatgg ggattctggc tgccaggctc ggatgaaata gcgattttat
    24661 tggggctggc gggtatggcg acgctactgg cggcgacaac tcatgcgccg ataatgtcca
    24721 ccctgatgat ttgtgaaatg accggcgagt atcagttact ccccggtctg ctgattgcct
    24781 gtgtagtcgc gtcagtgctc tcgcgaacgt tacgccatga ttctatctac cgccagcacg
    24841 ctgccgagca ttgacaaacg aatatactgc cccagctcac gctgctcggc gcgcggcagg
    24901 tacggtaact cgccaatcag cggcgctggc agttttttcc caagcacatc aataatttca
    24961 gcataatgcg ccaggccagg attgatacga ttcgccaccc agccaattaa gggcagtcca
    25021 tcattagcga cagcttgcgc agtcagtagc gcatgattaa tgcacccctc ctgaatcccc
    25081 accaccatca ataccggtaa ctgttcctgt accacccatt cggacaatgg acgtaaatca
    25141 ttcatcaaac tacgccagcc accagtgccc tccacaacca cgtggtccac tttatcgctc
    25201 agactcgcca gaccgttgga cagcaaggtg taatttatag gacagctatg cgcgacgctg
    25261 ctttcttctt cgcttaacgc gatcggatta atcgcctcat acggcaactc cagcgaagag
    25321 acgctttgca ataccagagc gtctttgttg cgcatccctt ctggagtctc tttgctccct
    25381 ttagcgacag gtttataccc tgcaacgctc ttaccacccg acgataacgc ttgtagtaat
    25441 gcgcgggaaa ccaccgtctt cccaacagaa gtgtctgtac ctgtaataaa gaaacgcttc
    25501 agcatcacta actccaccgt tatgcttcga aaatataagc caggaaaata atacagtgga
    25561 gaaagtctaa gatatggcaa gggcaatcag cttgagttag cgcaaatttt tgtacaacag
    25621 ttaaaaaatg ttaaccctgt aatagacgaa tcaacaaaga gccgttatac atcgcgtctt
    25681 ttaccaacgc cgccccggcc atcgtgctct ggttggtaaa ctgcgtgctt tccactaccg
    25741 tattcctact gtaggcgggc agcgcctgct gacggatact gtcagcaatg gccggaaaaa
    25801 gaatatcagc cgctttactt agcggcgaac caataagaat tttttgcgga ttaaataaat
    25861 tcaccatgat agccagaatg cgtccgacat gcgcgccaac gccgctaata atatcttttg
    25921 ctaatagatc tccctgcatc gccgcctgac acagcgaatc taccgttaac ggctggccat
    25981 gcaacattga acttatcgac tgattaagcc gaagctgcgt aagttccagc acactatcga
    26041 cgctggcgat ggtctccaga cagccatgat taccgcaata acagcgctta ccataaggat
    26101 tgacctgggt atgcccaatc tctaccagac tgctactgcc cgcatgaagc aaatgaccgt
    26161 cggtgataac gcccgccccc acattatgat caatcaccac ctggataacg tcgcgcgcgc
    26221 cgcgtgaggc gccaaaaagc gcctctgcca tcgtccaggc gctaatatca tgctgaatgt
    26281 aaaccggtac gccggtgtgc cgctccagcg catctcccaa aggcatctct ttgacatctt
    26341 cgtaatacgg catccggtgc acaacaccgt tttcggtatc gataatgccc ggtaacgtaa
    26401 tggcaatgga ggtcaaacgc tccagtttct gctgatggcg ggtaaaaaac cgatcaacgt
    26461 gcgtaataat tcgctcaagc aacggcgtag cttcgtttaa cggcagcgcc agacactctt
    26521 ctaccaccag tttgctgcta agatcgcgca gtgcaaggaa aatttcgcca cggctaatac
    26581 gaatagataa atagtgccag gcttccgttt ccaccatcag cccgacggcg ggacgtccac
    26641 gactgcccgc ctctttaatt tcaagttcct gaaccaaatg cgcttccagc atttcgcgaa
    26701 caattttcgt aatactggca ggcgccaact gcgccagacg agacaggtca attcgcgata
    26761 ccggtccgag ctgatcaatc aggcgataca ctgcgccagc attggtctgc ttaatttgat
    26821 cgatatgccc aggctgacta tcagcaacca ccgctcactc cctttatttt cgcgctccga
    26881 aataatctgt gtgctatggt gaaacacttc aatactcgcc gtcaactttt tgcttagccg
    26941 tgtgattaac tgcacatttt cacccttttt aagcgtaatt aatcctgtcg ggcagccagt
    27001 aatagcagtt ggcaaaaccg ctgtacggca tgactctgtt catgatgctt tggccatacc
    27061 agccacattt cagatacggc gtcctcttct gccaggggaa cccagcgcat ctcgctcatc
    27121 tgtacacgct taaaggatgc cggcagaatc gagacgccca gtcccgccgc caccagaccg
    27181 ataatagtca ttgcctcgcc aacctcctgc gtgatggtcg gcgacaggtt atagcgccgc
    27241 atcaggccga gaatatcgtc gtagagaccc gtcccgacat gcggatcgaa aaagacgaaa
    27301 ggttcttccg ccagttctgt cagactgacg actggctttt gcgccagccg atgttcgcgc
    27361 gggatcatgg ccataagcgg ctcatgcaaa atcacctcgc gattaagtgt gtctggcagc
    27421 ggcgtattcc gcagcaagcc aatatccagt acgccttcgt tgagcggcgc gatttgctca
    27481 cgcgtattca tttcacgcgt ttgcatatgc acccccggat aggactggcg gaacaacgaa
    27541 aaggtatgcg ataccgcccg aataaaaggc gctgaagacg taaaaccaat acggatttcg
    27601 cccgcttcgc cctgatgcaa ccgctcggcg cgagcggcgg cgtcgtttac cagactcagg
    27661 atgtgtcggc tatccgccag aaactgtcgc ccggcggcgg ttaacgctac gctgcggttg
    27721 gtccgcgcca gtaatcgcgc accgacctgc tgctccagaa tttgtatctg ctgactgagc
    27781 ggcggctgcg agatattgag gcgcgcg
//
LOCUS       DAJVKX010000052        26750 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000052 DAJVKX010000000
VERSION     DAJVKX010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26750
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.052"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(203..457)
                     /locus_tag="OPY25_002278"
     CDS             complement(203..457)
                     /locus_tag="OPY25_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HCS0927882.1"
                     /translation="MDCRSGCGACCIAPSISSPIPGMPNGKPMNTRCVQLSEDNLCLI
                     FGSPLRPKVCSGLQPTGDMCLTTREEAIIYLLELEQKTLP"
     gene            782..1354
                     /gene="yeiP"
                     /locus_tag="OPY25_002279"
     CDS             782..1354
                     /gene="yeiP"
                     /locus_tag="OPY25_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HCS0927883.1"
                     /translation="MPRANEIKKGMVLNYNGKLLIVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLSRRGVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSAGEKIRIHIEERRYMGRAD"
     gene            1567..2553
                     /locus_tag="OPY25_002280"
     CDS             1567..2553
                     /locus_tag="OPY25_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCS0927884.1"
                     /translation="MTKTNLITGFLGSGKTTSILHLLAHKDPAEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDQQSVANENFRDQLASADIIIANKTDRATAQ
                     SDAALQQWWRQYGGDRQLIHAEHGQIDGKLLDLPRQNLAELPASAAHSHTHASKKGLA
                     ALNLPAQQRWRRSLNSGQGHQACGWIFDADTVFDTIGLLEWARLAPVGRVKGVMRIQE
                     GLVRINRQGDDLHIETQSVAPPDSRVELISNTETDWNTLQTALLKLRLATHA"
     gene            2583..3302
                     /locus_tag="OPY25_002281"
     CDS             2583..3302
                     /locus_tag="OPY25_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCS0927885.1"
                     /translation="MTMKTRYSLIILLNAAGLALFLSWYLPVNHGFWFTIDSGIFHFF
                     NQKLVESHAFLWWVAITNNRAFDGCSLLAMGGLMLSFWLKEDASGRRRIVIIGLVMLL
                     TAVVLNQLGQALIPVKRASPTLSFEHIYRVSELLHIPTKDASKDSFPGDHGMMLLIFS
                     AFMLRYFGKTAGIIALIIFVVFAFPRVMIGAHWFTDIVVGSLTVILIGLPWWLMTPLS
                     DRAIALFEDYLPGGNKQILNK"
     gene            3716..4288
                     /gene="mepS"
                     /locus_tag="OPY25_002282"
     CDS             3716..4288
                     /gene="mepS"
                     /locus_tag="OPY25_002282"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HCS0927886.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSTTTNTAKNMHSETHAV
                     GNSDSSSLQASQDEFENMVRNLDVKSRIMDQYADWKGVRYRLGGSTKKGVDCSSFVQR
                     TFREQFGLELPRSTYEQQEMGKAVSRNNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHA
                     STSSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            4614..6170
                     /locus_tag="OPY25_002283"
     CDS             4614..6170
                     /locus_tag="OPY25_002283"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HCS0927887.1"
                     /translation="MLTRDSSSGRKILLTCIITGIAAALLIGSLQFFLSWHKRDVKYN
                     TLLSDVQHYLASYFADLKATTDILQPLTINTCQQVGAELTSRAAFSLNVRAFLLIKDK
                     KVFCSSATGAMNMPLQQLVPDIDIRKDVAMAILPGTPMMPNKPTMVIWYRNPLLNNSG
                     VFTSLNINLTPYLLYTTRQDDFNGIALIVGNTALSTFSSRLLTVAELPGTPSRQATIN
                     GLPLKIQLYADSWTYNDLWYALMLGCISGIVAGFICYFIYALRTRPGKEILTAIKHEQ
                     FYVVYQPVVDTRTLSVTGLEVLLRWRHPTAGEIPPDAFIHYAEAQQLIVPLTQHLFEL
                     IARDAPTLQKVMPVGAKFGINIAPEHLHSDSFKEDMHRLRDALPAHHFHIVLEITERN
                     MLQQYEAAKLFEWLHSAGFEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTET
                     VTSPVLDTVLTLSRRLNMLTVAEGVETPEQARWLRDHGVNYLQGYWISRPLPLKDFVL
                     WMSAPSVPEW"
     gene            6277..8082
                     /locus_tag="OPY25_002284"
     CDS             6277..8082
                     /locus_tag="OPY25_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCS0927888.1"
                     /translation="MIARVMLLLVALVSAGAQAQEIKESYAFAVLGEPKYAFNFDHFD
                     YVNPAAPKGGQMTLSAIGTFDNFNRYSLRGNPGVRTEALYDTLFTTSDDEPGSYYPLI
                     ADHARYAADYSWVEISINPRARFHDGTPITARDVAFTFHKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPIMPEKFWKNHKLSDPLSTPPLASGPYRITQW
                     KMGQYIVYSRVKNYWAANLPVNRGRFNLDTVRYDYYLDDNVAFEAFKAGAFDLRLEND
                     AKNWATRYIGKNFDNHYIIKEEQKNESAQDTRWLAFNIQRPVFKDRRVREAVTLAFDF
                     EWMNKALFYNAWSRTNSYFQNTEYAARNYPDADELVLLAPMKKDLPPEVFTQIYQPPV
                     SNGDGYDRENLLKADALLTQAGWVINGQQRVNSVTGKPLTFELLLPASSNSQWVLPFQ
                     HNLQRLGITMTIRQVDNSQLTNRMRSRDYDMMPRLWRAMPWPSSDLQISWASEYIDSS
                     YNAPGVQSPVVDKLIAQIIAAQGDKAKLVPLGRALDRVLTWNYYMLPMWYMAQDRLAW
                     WDKFSHPAIRPVYTIGLDTWWYDVNKAAKLPAARR"
     gene            8092..9186
                     /locus_tag="OPY25_002285"
     CDS             8092..9186
                     /locus_tag="OPY25_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HCS0927889.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GQGGALPGASGEGVRASHAQTGVGNISDSHYRGGRGLDPEVIAEITHRYGFDKPLHER
                     YFKMLRDYLSFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     HNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYYDIFPLRGLVSANFDTLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNILSDISYTLVDPRIDFEGR"
     gene            9186..10211
                     /locus_tag="OPY25_002286"
     CDS             9186..10211
                     /locus_tag="OPY25_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0927890.1"
                     /translation="MPRLSPVNQARWARFRHNRRGYWSLWIFLVVFSLSLCAELIAND
                     KPLLVRYEGQWYFPLVKNYSERDFGGPLATTADYQDPWLQRQLENRGWVLWAPVRFGA
                     NTINFATTQPFPSPPSAKNWLGTDANGGDVFARILYGTRISILFGLMLTICSSVMGVL
                     AGALQGYYGGKVDLWGQRLIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRDIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGIAAFLSVAILLSLLIFIGEAVRDA
                     FDPAKAV"
     gene            10213..11802
                     /gene="yejF"
                     /locus_tag="OPY25_002287"
     CDS             10213..11802
                     /gene="yejF"
                     /locus_tag="OPY25_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HCS0927891.1"
                     /translation="MTSPLLAIENLSVGFRQQQHVRPVVNAISLQVNAGETLALVGES
                     GSGKSVTALSILRLLPTPPAVYLSGDIRFHGESLLHASEQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARAEMIGCLDRVGIRQASQRLRDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILSLLRELQRELNMGLLFITHNLS
                     IVKKLADSVAVMQHGKCVENQRADTLLSAPTHPYTQKLLNSEPTGDPVPLPAGQAPLL
                     EVDKLRVAFPIRKGILKRVVDHNVVVNNISFTLHPGETLGLVGESGSGKSTTGLALLR
                     LIRSEGRIVFDGQSLDTLNRRQLLPVRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSGAQREQQVKAVMMEVGLDPETRHRYPAEFSGGQRQRIAVARALILKPSLIILD
                     EPTSSLDKTVQAQILALLKSLQQKHRLAYIFISHDLHVVRALCHQVIVLRQGEVVEQG
                     QCERVFTAPQQAYTRQLLALS"
     gene            complement(11806..12150)
                     /locus_tag="OPY25_002288"
     CDS             complement(11806..12150)
                     /locus_tag="OPY25_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927892.1"
                     /translation="MNTLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGQSTENSLVAL
                     KLLSPAGDSAWSVMHKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNNNPF"
     gene            complement(12541..13731)
                     /locus_tag="OPY25_002289"
     CDS             complement(12541..13731)
                     /locus_tag="OPY25_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HCS0927893.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSAQMTLSTYILGFALGQLIYGPMADSLGRKPVILGGTLVFAAAAVACALAQTIDQLI
                     VMRFFHGLVAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILAIAAILASVMIFALIKETLPVERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVPPQDFGYYFALNIVFLFVMTIINSRFVRRV
                     GALNMFRAGLWIQFAMAVWMVFSALMGIGFWALVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIALCAACSILFYLYASR
                     PKKR"
     gene            complement(13759..14454)
                     /gene="rsuA"
                     /locus_tag="OPY25_002290"
     CDS             complement(13759..14454)
                     /gene="rsuA"
                     /locus_tag="OPY25_002290"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HCS0927894.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGDIIKNAAFKLLPE
                     HAVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAYKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAAQFAKGVQLHNEKDL
                     TKPATLEVITPVQVRLTISEGRYHQVKRMFAAVGNRVVELHRERIGAITLDENLAPGE
                     YRPLTEEEIASVG"
     gene            14606..16366
                     /locus_tag="OPY25_002291"
     CDS             14606..16366
                     /locus_tag="OPY25_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCS0927895.1"
                     /translation="MIFTLRPYQQEAVDATLSHFRRHRTPAVIVLPTGAGKSLVIAEL
                     ARVARGRVLVLAHVKELVAQNHAKYCALGLEADIFAAGLKRKESQGKVVFGSVQSVAR
                     NLDAFQEEFSLLIVDECHRIGDDEDSQYQQILTHLSKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGNDNALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAQTRKGVMIFAATVEHAKEIVGLLPADD
                     AALITGDTPGPERDALIDNFKAQRFRYLVNVSVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGSPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDAILVDPDDMLKAALRLKDALVLRCSGMTMQHGQDEKGEWLKITYYDEDGADVSERF
                     RLHTPAQRTAFEQLFIRPHTRTPGVPLRWITAADIVAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRRAHELRG"
     gene            16491..16775
                     /gene="rplY"
                     /locus_tag="OPY25_002292"
     CDS             16491..16775
                     /gene="rplY"
                     /locus_tag="OPY25_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HCS0927896.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDH
                     DQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA"
     gene            complement(16884..17504)
                     /locus_tag="OPY25_002293"
     CDS             complement(16884..17504)
                     /locus_tag="OPY25_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927897.1"
                     /translation="MSKGIRQRPPVNFSLFRQVLYAHIVAFLMMLMLGMVFTVLSLVL
                     FYTYGANWLLSLFICPLFLLSGLFITGFAFKSTWSSIRYYYDKGQLKRYGLNLDATLT
                     HKEKVEIRIDNAKRQVRVDELELHVLFDFQFDSKTWSCGDLLTNEKVFDALNDGQTIP
                     IRILPWKPESASVRQRALFNRLKGMNTAAETTDPRLGEALIECGEV"
     gene            complement(17532..18539)
                     /gene="yejK"
                     /locus_tag="OPY25_002294"
     CDS             complement(17532..18539)
                     /gene="yejK"
                     /locus_tag="OPY25_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HCS0927898.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELH
                     RVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGI
                     VLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADR
                     STLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     K"
     gene            18719..18946
                     /locus_tag="OPY25_002295"
     CDS             18719..18946
                     /locus_tag="OPY25_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HCS0927899.1"
                     /translation="MPQLSRYSDEHVEQLLSELLSVLEKHKAPTDLSLMVLGNMVTNL
                     INTSVAPAQRQAIANSFARALQSSISEDNAH"
     gene            18978..20738
                     /gene="pbgA"
                     /locus_tag="OPY25_002296"
     CDS             18978..20738
                     /gene="pbgA"
                     /locus_tag="OPY25_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HCS0927900.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLATLLGSRYLFVADWP
                     TTLAGRIYSYLSIVGHFSFLVFATYLLILFPLTFIVMSQRLMRFLSAILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWELVINPDQNEMARDWQLMFISVPVILLIEMLFATWSWQKL
                     RSLTRRRHFARPLAAFFFVSFIASHLIYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLVEQGNPEAVSVQYPLSNLHYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPELATFAEQNIDFTRHMSSGNTTDNGIFGLFYGISPGYMDGVLSTRTPAALITAL
                     NQQGYQLGLFSSDGFASPLYRQALLSDFSMPAAQTQSDAQTASQWIDWLGRYAQEDNR
                     WFSWISFNGTNIDDSNQKNFVKRYASAASDVDAQINRVLNALREAGKFDNTVVIITAG
                     RGIPLTPEENRFDWSQGHLQVPLVIHWPGTPAQRINVLTDHTDVMTTLMQRLLHVSTP
                     ANEYSQGQDIFTVPRRHNWVTAADGSTLAITTPQMTLVLNNNGHYQTYDLHGEKIKDQ
                     KPQLSLLLQVLTEEKRFIAN"
     gene            20812..20888
                     /locus_tag="OPY25_002297"
     tRNA            20812..20888
                     /locus_tag="OPY25_002297"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20846..20848,aa:Pro,seq:ggg)
     gene            complement(21199..21421)
                     /locus_tag="OPY25_002298"
                     /pseudo
     CDS             complement(21199..21421)
                     /locus_tag="OPY25_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457616.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
     gene            complement(21509..23875)
                     /gene="sspH2"
                     /locus_tag="OPY25_002299"
     CDS             complement(21509..23875)
                     /gene="sspH2"
                     /locus_tag="OPY25_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector E3
                     ubiquitin transferase SspH2"
                     /protein_id="HCS0927901.1"
                     /translation="MPFHIGSGCLPATISNRRIYRIAWSDTPPEMSSWEKMKEFFCST
                     HQTEALECIWTICHPPAGTTREDVINRFELLRTLAYAGWEESIHSGQHGENYFCILDE
                     DSQEILSVTLDDAGNYTVNCQGYSETHRLTLDTAQGEEGTGHAEGASGTFRTSFLPAT
                     TAPQTPAEYDAVWSAWRRAAPAEESRGRAAAVQKMRACLNNGNAVLNVGESGLTTLPD
                     CLPAHITTLVIPDNNLTSLPALPPELRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTH
                     LPALPSGLCKLWIFGNQLTSLPVLPPGLQELSVSDNQLASLPALPSELCKLWAYNNQL
                     TSLPTLPSGLQELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSGLKELIVSGN
                     RLTSLPVLPSELKELMVSGNRLTSLPMLPSGLLSLSVYRNQLTRLPESLIHLSSETTV
                     NLEGNPLSERTLQALREITSAPGYSGPIIRFDMAGASAPRETRALHLAAADWLVPARE
                     GEPAPADRWHMFGQEDNADAFSLFLDRLSETENFIKDAGFKAQISSWLAQLAEDEALR
                     ANTFAMATEATSSCEDRVTFFLHQMKNVQLVHNAEKGQYDNDLAALVATGREMFRLGK
                     LEQIAREKVRTLALVDEIEVWLAYQNKLKKSLGLTSVTSEMRFFDVSGVTVTDLQDAE
                     LQVKAAEKSEFREWILQWGPLHRVLERKAPKRVNALREKQISDYEETYRMLSDTELRP
                     SGLVGNTDAERTIGARAMESAKKTFLDGLRPLVEEMLGSYLNVQWRRN"
     gene            complement(24044..24247)
                     /locus_tag="OPY25_002300"
     CDS             complement(24044..24247)
                     /locus_tag="OPY25_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0927902.1"
                     /translation="MPDTDENRRADIHAAGSLKTVKSFKGFIRRKSCAGRQNRKLNAR
                     ALIPDDLVIVESDPEKIDTLAVK"
     gene            complement(24544..25335)
                     /locus_tag="OPY25_002301"
     CDS             complement(24544..25335)
                     /locus_tag="OPY25_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCS0927903.1"
                     /translation="MISLEDASLTKKGIVKLSSATDSDSEALAATPKAVKTVMGEVRT
                     KAPLDSPAFTGTPTTPTPPGDAKGLQTTNAEFVRKLIAALVGSVLEPLDTLQELADAL
                     GNDPNFATTVLNKLAGKQPLDETLTALSGKSVDGLIEYVGLRETISRAADALQKSQNG
                     GDIPDKDLFVRRIGAARAFDGAVIIGCDDNPWTTAEFIVWLESQGAFNHPYWMCRGSW
                     SYAYNKIITDTGCGNICLAGAVIEVMGVRGAMTIRVTTSHSVSGW"
     gene            25451..25609
                     /locus_tag="OPY25_002302"
     CDS             25451..25609
                     /locus_tag="OPY25_002302"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927904.1"
                     /translation="MDAYDADDEAAAAVLAVSADAALADASPAFVVAVPALLSADAAD
                     EAADQNSP"
     gene            25638..25841
                     /locus_tag="OPY25_002303"
     CDS             25638..25841
                     /locus_tag="OPY25_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence protein MsgA"
                     /protein_id="HCS0927905.1"
                     /translation="MPTIKKLADARDVILHELILHELIGHLSCAVVTVKSMQATNVNH
                     VCTKTEKAHLHPILEKMFAVAGK"
     gene            complement(26033..26497)
                     /locus_tag="OPY25_002304"
     CDS             complement(26033..26497)
                     /locus_tag="OPY25_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyloxyacyl hydrolase"
                     /protein_id="HCS0927906.1"
                     /translation="MSFAAGESIRRGGVEHLYTAFLTYSEPSDFFFLQARNNLELGGF
                     KAKGSDDCSKHSGSVPCNKYNQGVLGISKDVALVHFAGIYTGIGLGAYIKSKSRDDMR
                     VNSAFTFGEKAFLGWNFGAFSTEAYIRHFSNGSLTDKNSGHNFVGASISYNF"
BASE COUNT         6366 a         7288 c         6570 g         6526 t
ORIGIN      
        1 acgttcaggc accaacgggg ttgagcggcg acatctaccg tttcagaaga cacgaaataa
       61 gggaagcatg tattacgcta tttaatggta aaaggaggta atttgatgcg cagcttttgc
      121 agactatttc gggatataac gtaagcccct gcacgtttat caaaaacagc tgacttagag
      181 cctatcccat taggctatta gctcatggta aggttttctg ttcgagttcc agcaaataaa
      241 taatggcctc ttcccgggtc gttaaacaca tgtcccctgt cggttgcaaa ccagagcaca
      301 cttttgggcg taaaggcgag ccaaagataa gacacaagtt atcttccgaa agctgcacgc
      361 atctggtatt catcggcttg ccattcggca ttccgggtat cggcgacgaa attgaaggcg
      421 caatacagca agcgccacaa ccgctacgac agtccatgct cagcccctct atttataacc
      481 aaatgaaaga taacagaatt tgtccaaaga aaaatccaga tttaaaatgt ggacgtcatc
      541 atgatcaggc ctgtcctcag acattccgaa gacaaggctg gaaacagaag ggacaacaca
      601 gcacacttcc cccctccagg cgacatgcca tcgcgtattc tcgttgaacg cggagcggaa
      661 agcgggcgaa cagtatcacc ttttttgcac cagcaaaagt gacaattcca cttgcctgga
      721 cggcccggcg cgagtagttt tacgcgatat tttagataat ctctacaaca ggatctcctc
      781 gatgccaaga gcgaacgaaa tcaaaaaagg tatggtactg aactacaacg gcaaattgct
      841 gattgtgaaa gatatcgaca ttcagtcgcc taccgcccgt ggcgccgcca cactgtataa
      901 aatgcgcttt tccgatgtcc gcaccggtct gaaagtggaa gaacgtttca aaggcgacga
      961 tatcgttgat accgtcaccc tgagccgtcg cggcgttgac ttttcttatg tcgatggcaa
     1021 cgaatatgtg ttcatggata aagaagacta tacgccgtat accttcacca aagatcagat
     1081 tgaagaagag ttgctgttta tgcctgaagg cggaatgccg gatatgcagg ttctgacctg
     1141 ggacggccaa ctgctggcgc tagagcttcc gcagaccgtg gatctggaaa tcgtcgaaac
     1201 cgcgccgggt attaaaggag cgtccgccag cgcacgtaac aaacccgcga cattaagcac
     1261 cggtctggtg attcaggttc ccgaatacct gagcgcaggt gagaaaatcc gcattcatat
     1321 cgaagagcgc cgttatatgg ggcgcgcgga ttaagtttca catttttcgg ctgcgcccca
     1381 gggcgcagtc tgcccctttt atttattgac tgttctgcac caggcaagag aaacgttaaa
     1441 aatttaacat tttctgctct taagatggca gaagcacgac ttcgtcaact cagcacttct
     1501 ctttttcacg tttattcgcc aggattatta aaagttgtta tgttgtatca atattctgga
     1561 gctgacgtga ccaaaaccaa tcttattact ggatttctcg gtagcggaaa aaccacctct
     1621 atccttcatt tattagctca taaagatccg gctgaaaagt gggccgtcct ggttaatgaa
     1681 tttggtgaag tgggtattga cggcgcgctg cttgccgaca gcggcgcact gctaaaagag
     1741 attcccggcg gctgcatgtg ctgcgtcaac ggattgccta tgcaggtggg gctcaacacg
     1801 ctgctgcgcc agggcaaacc tgaccggttg ctgattgaac caaccggact ggggcaccca
     1861 aaacagattc tggatttatt aactgcgccg gtttatgagc cgtggattga tttacgcgcc
     1921 acgctctgca tcctggaccc tcgcctgcta ctggaccaac agagcgtcgc caatgaaaat
     1981 ttccgcgatc agctcgcctc agccgatatt atcatcgcca ataaaaccga ccgcgccacg
     2041 gcgcagagcg atgccgccct gcaacagtgg tggcgacagt acggcggcga tcgtcaactg
     2101 attcatgccg aacatggaca gatagacggt aagcttctgg atttaccgcg acaaaatctg
     2161 gcggaactgc cggccagcgc cgcgcattct cacactcatg ccagtaaaaa aggactcgcc
     2221 gcgctaaatc tgcccgcaca gcagcgctgg cgacgcagcc tcaatagcgg acagggtcat
     2281 caggcctgcg gctggatttt cgatgccgat accgtgtttg acaccattgg cctactcgaa
     2341 tgggctcgtc tggcgccggt gggccgggtg aaaggcgtta tgcgcataca agaggggctg
     2401 gtacgcatca atcgccaggg cgatgacctg cacatcgaaa cacagagtgt cgcgccgccg
     2461 gatagccggg ttgaacttat ctcaaacaca gaaaccgact ggaatacgtt acagacggcc
     2521 ttgttgaagc ttcgtttagc gacgcacgcg taaggttgcc accgtttaaa aactatggcg
     2581 aaatgacgat gaaaacccgc tattccttga taattctgct taatgccgcc ggtctggcgc
     2641 tgtttttgtc atggtatctt cccgtcaatc acggtttctg gttcaccatt gattccggca
     2701 tattccactt ctttaaccag aaactggtgg aaagccacgc gttcctctgg tgggtcgcta
     2761 ttaccaataa tcgggcgttt gacggctgtt cgctgctggc gatgggcgga ctgatgctca
     2821 gtttctggct aaaagaagac gcgtcgggcc ggcggcgcat tgtgataatc ggattggtca
     2881 tgctgctaac agcggtggtg cttaaccaac tcggtcaggc gctgatcccc gtcaagcgcg
     2941 ccagtccaac gctctctttt gagcatattt atcgcgtcag cgagttgctg cacatcccga
     3001 caaaagacgc gtcaaaagac agtttcccag gcgatcacgg tatgatgctg ctgatatttt
     3061 ccgcctttat gctgcgttat ttcggcaaaa cggcggggat tatcgccctt attatatttg
     3121 tggttttcgc gtttccgcgc gttatgattg gcgctcactg gttcaccgat attgtggttg
     3181 ggtcgctcac ggttattttg attggcctcc cctggtggct gatgaccccg ctcagcgacc
     3241 gggcgatagc gctttttgag gattatctcc cgggcggaaa taaacaaatt ttaaacaaat
     3301 aacccataca attaacattg ccttcagcga tagttttaca tcgttgaagg taatttatga
     3361 tgatattccc ccagcccatc atttttcggt aatattattc ctctgcaaaa tgaacaggtt
     3421 gcacgatttt taaacgattt gcgcttaatt tgacccgtgc tgatagctca cttttcgtat
     3481 cataaattct tataaaaaat cacgcgaaat cgctcgcaat gacagcaaca atcgggtaat
     3541 ctcaaactcg ttttgcctcg ccagataatt attctcattg cgaataaatt tgtgcgttcc
     3601 gccacagatt tgtgcacaaa gaattgtctc aagctgtgca ggtaattagt ctcatcacgt
     3661 ttggcatttt tataacgata tttatcgtta aggacttcaa gggaaaacaa acaacatggt
     3721 caaatctcaa ccgattttga gatatatttt gcgcgggatt cctgcgattg cagttgcggt
     3781 tctgctttct gcttgtagca caaccaccaa taccgcaaag aatatgcatt ctgagacgca
     3841 tgctgtgggc aatagcgata gctcttcact gcaagcctct caggatgaat ttgaaaatat
     3901 ggtgcgtaac ctcgacgtta agtcgcggat tatggatcag tatgctgact ggaaaggtgt
     3961 gcgttaccgc ctgggcggca gcactaagaa aggcgtcgac tgttccagct ttgtacagcg
     4021 caccttccgc gaacagtttg gtttagagct tccgcgttca acctatgaac agcaggaaat
     4081 gggcaaagcg gtttcacgca ataacctgcg tacgggcgat ctggttctgt tccgcgccgg
     4141 ttccactggc cgtcatgtcg gtatttatat cggcaataac caatttgtcc atgcgtctac
     4201 cagtagcggc gtcattatct ccagtatgaa cgaaccgtac tggaaaaaac gctacaatga
     4261 agcgcgtcga gttctgagcc gcagttaatc ttcatcaggc agcacctccc ttggcttacc
     4321 tgatgagacg acataaaaag cactgcttca gcagtgcttt tgcttattat cccttctgaa
     4381 cccgttttac cgaatagcga cgtgtcgcct cttatccagc ctacaacaca cgaacatagg
     4441 cctgataaac atagcgccat cagacattca ggtcgtttcc gccaacgact actgcgacaa
     4501 tacgctttcc tgcgcatcac agaaaagcat gactatccgg ggtaatccag gctatagtct
     4561 tataaatcaa ccagtttaac cggcatctgc cttttcaggt cacaccagga attatgctta
     4621 cacgcgactc ctcttccggt cggaaaatcc tgcttacctg tatcattacg gggatagcgg
     4681 cagcattact tattggtagc ctgcaatttt tcctgtcgtg gcataaacgg gatgttaaat
     4741 acaatacgct cctttctgat gtacaacatt acctagccag ctatttcgcc gacctgaaag
     4801 ccaccaccga tattcttcag ccgttgacga tcaacacctg tcagcaggtt ggcgcagaac
     4861 tcacctcaag agccgctttt agccttaatg tccgcgcctt cttattgatt aaagataaaa
     4921 aagtgttctg ctcttccgcc actggcgcca tgaatatgcc gcttcagcaa ctggtaccgg
     4981 atatagatat ccgcaaagac gttgctatgg cgattctgcc cggcacgcca atgatgccca
     5041 acaaaccgac aatggtgatt tggtatcgaa acccattatt aaataacagc ggcgtattca
     5101 catcgctgaa tattaacctg acgccctact tactctatac cacgcgccag gacgatttta
     5161 acggcatcgc gctgattgtc ggcaataccg cgctgtcgac cttttcttcg cgtctgctga
     5221 ccgtcgcgga gctgccgggc acgccttcac gacaggcaac tatcaacggc ctgccgctta
     5281 aaatacagct ttatgccgat agctggacct acaatgactt gtggtatgcg ttgatgctgg
     5341 gctgcattag cggcatcgta gcggggttta tctgttactt tatctatgcc ctccggacgc
     5401 gaccgggcaa agagatttta acggcgatca aacacgagca gttttatgtg gtttatcagc
     5461 ccgtcgtcga tactcgtacg ctaagcgtca ccgggcttga agtcttactg cgctggcgtc
     5521 accctacggc aggcgagatt ccgccggatg cctttatcca ctatgccgaa gcgcagcaac
     5581 ttatcgtacc gttaacgcag catctgttcg agctgatcgc ccgcgacgca cccacgctac
     5641 agaaggtgat gcccgtcggt gccaaatttg gcattaacat cgcgccggaa catctgcaca
     5701 gcgacagttt taaagaggat atgcaccggc tcagggacgc cctgcccgcg caccattttc
     5761 atatcgtgct ggaaatcact gaacgcaata tgcttcagca gtatgaagcg gccaaactgt
     5821 tcgaatggct gcattccgcc gggtttgaaa tcgctataga tgatttcggt acaggccata
     5881 gcgccctgat ttatctggag cgatttactt tagattatct gaaaattgat cgcggcttta
     5941 tccaggcgat cggcacggaa accgtcacgt ctccggttct ggataccgtg ctgacgctct
     6001 ccagacgcct gaatatgctg acggtggccg agggcgttga aacgccggag caggcccgtt
     6061 ggctacgcga tcacggtgtt aattacttgc aggggtactg gattagccgt cctttacccc
     6121 taaaagattt cgtgctgtgg atgtcggcgc cttccgtgcc tgaatggtag tccccttacg
     6181 gttttaacgg attcacatca gacgcaacgt cacttattat tcagcgaaac gcctgccggt
     6241 ttgcagcggg caatacgata aggaaaccgc cttcagatga ttgcgcgcgt aatgcttctg
     6301 cttgtcgcac tggttagcgc tggcgcccag gcccaggaaa tcaaagaaag ctacgctttc
     6361 gccgtactcg gcgaacctaa gtatgctttt aactttgatc actttgatta tgtgaatcct
     6421 gctgcgccga aaggcggtca gatgacgctt tccgccattg gtacgttcga taatttcaat
     6481 cgctattcgc tgcgcggcaa tcccggcgta cgtaccgaag ccctttacga tacgcttttt
     6541 accacctcgg atgatgaacc cggaagctat tacccgctga ttgccgacca tgcccgctat
     6601 gccgccgact attcctgggt ggaaatctcg attaaccccc gcgctcgttt tcacgatggc
     6661 acgcccatta ccgcccgcga tgtagccttt acctttcata agtttatgac cgaaggcgta
     6721 ccgcagttcc gtctggtcta taaaggtact accgtgaagg cgattgcgcc tttaaccgtg
     6781 cgaattgagc tggcgaagcc tggtaaagaa gacatgctta gtctgttttc actaccgatc
     6841 atgcccgaaa aattctggaa aaatcacaaa ctcagcgatc cactttcaac gccgccctta
     6901 gccagcgggc cataccggat tactcagtgg aaaatgggcc agtacattgt ctattcacgc
     6961 gtcaaaaact actgggcggc taatctgccg gtcaatcgtg gacgttttaa cctcgacact
     7021 gtccgctacg attactacct tgatgacaat gtcgctttcg aggcgtttaa agcgggcgca
     7081 tttgatctac ggctggaaaa cgacgctaaa aactgggcaa cgcgctatat cggtaaaaat
     7141 ttcgataatc attacatcat taaagaagag cagaaaaacg agtcggcgca ggacacacgc
     7201 tggctggcct ttaatattca gcgcccggta tttaaagacc ggcgggtacg tgaagccgtc
     7261 accctggcct tcgattttga gtggatgaat aaagcgctgt tctataatgc ctggagccga
     7321 accaacagtt acttccagaa taccgagtac gccgccagaa attatcctga cgccgacgaa
     7381 ctggtattac tcgcgccgat gaaaaaagat cttcctcctg aagtcttcac tcagatctat
     7441 cagccgccgg tctctaacgg cgacggctac gatcgcgaaa atcttcttaa agctgacgcc
     7501 ttgttgacgc aggccggatg ggtgatcaac ggacagcaac gggtcaatag cgtcaccggt
     7561 aagcctctga cgtttgaact tctccttcct gccagcagta atagccagtg ggttctgccc
     7621 ttccagcata atcttcagcg tctgggcatt acgatgacta tccgtcaggt tgataattct
     7681 caactcacca accggatgcg tagccgcgac tatgacatga tgccgaggct atggcgggcg
     7741 atgccctggc ccagctccga tctacaaatc tcatgggcgt cggaatacat tgactccagt
     7801 tataacgctc ccggcgtaca aagcccggtg gtggataagc tgatcgcgca aattatcgca
     7861 gcgcagggtg ataaagcgaa actggtgccg ctgggacggg cgctggatcg cgtgctgacc
     7921 tggaactatt acatgctgcc gatgtggtat atggcgcaag acaggctcgc ctggtgggat
     7981 aaattctccc atccggcgat tcgcccggta tataccatcg ggttagatac ctggtggtat
     8041 gatgtcaaca aagccgccaa gctaccggca gccaggaggt agtaagaatc aatgggtgcc
     8101 tatcttatcc gccgtctgtt actggtgatc cccacgctat gggccattat taccattaac
     8161 ttttttatcg tgcagatcgc tcccggcggc cctgtcgatc aggctattgc cgcgattgaa
     8221 tttggtcagg gcggcgcgtt gcccggcgcc agcggcgaag gcgttcgcgc cagtcatgcg
     8281 caaaccggcg tcggcaatat cagcgacagc cattatcgcg gcggccgggg actcgatccg
     8341 gaggtgatcg cggagatcac ccatcgctac ggcttcgaca aaccgctgca tgagcgttat
     8401 ttcaagatgc tacgggacta tctctctttt gacttcggcg acagtctgtt tcgcagcgca
     8461 tccgtactaa cgctgatcaa agatagcctt cccgtctcca ttaccctggg attatggagc
     8521 acgctgatta tttatctggt gtctatcccg ctggggattc gcaaagccgt ccataacggc
     8581 agtcgctttg atgtgtggag cagcgcgttt atcattattg gttatgcgat ccccgccttt
     8641 ctgttcgcta ttttattaat cgtctttttt gccggcggca gctactacga tatctttccg
     8701 ctacgtggcc tggtctccgc caactttgac acgttaccgt ggtaccagaa aatcaccgat
     8761 tatttgtggc atattacgct gccggtgttg gcgaccgtca tcggcggttt tgccgccctg
     8821 acgatgctga cgaaaaattc gtttctcgac gaggtgcgta aacagtatgt cgttaccgct
     8881 cgcgctaaag gcgtgagtga aaaaaacatt ctctggaaac atgtttttcg taacgccatg
     8941 ctgctggtga tcgccgggtt tcccgccact tttatcagta tgtttttcac cggctcgttg
     9001 ctaattgaag tcatgttctc gctcaacggc ctggggctgc tgggttatga agcaaccgtt
     9061 tcgcgcgact atccggtgat gttcggcacg ctttatatct ttaccctgat tggcttatta
     9121 ctgaatatcc tgagcgatat cagctatacg ctggtcgatc cacgcattga ttttgaggga
     9181 cgataatgcc gcgattaagc ccggtcaatc aggcccgctg ggcgcgtttc cgccataatc
     9241 gccggggcta ctggtcacta tggattttcc tggtagtgtt cagcctgagc ttatgcgcgg
     9301 aactgattgc taacgataag ccattgctgg tgcgctatga aggccagtgg tattttccgc
     9361 tggtaaaaaa ttacagcgag cgcgatttcg gcggcccgct ggcgacaacg gcagactatc
     9421 aggacccctg gctacaacgg cagcttgaga atcggggctg ggtgttgtgg gcccccgtac
     9481 gctttggcgc caataccatt aattttgcca ccacgcagcc tttcccctcc ccgccttcgg
     9541 cgaaaaactg gctgggcacc gatgcgaatg gcggcgacgt tttcgcccgc atcctgtacg
     9601 gcacccgcat ttctatttta tttggcctga tgttaacgat ttgctccagc gtcatgggtg
     9661 tactggcggg cgcgctacag ggctattatg gcggcaaagt cgatttatgg gggcaacgtc
     9721 tcatcgaagt ctggtcgggg atgccgaccc tgtttctgat tattttactt tccagcgtag
     9781 tgcagcctaa cttctggtgg ctgctggcca taaccgtgct gtttggctgg atgagtctgg
     9841 tgggcgtggt gcgcgccgag tttttacgga cccgcaattt tgactatatc cgcgccgcgc
     9901 aggcgcttgg cgtcagcgat cgtgacatta tcctgcgcca tatgttgcct aatgcgatgg
     9961 tcgctaccct gacattttta ccgttcattt tatgtagttc catcaccacc ctgacgtcgc
    10021 tggattttct gggattcggt ctgccgcttg gctccccttc tctcggcgaa cttcttttac
    10081 aggggaaaaa caacttacag gctccctggc tggggatcgc cgcctttctg tctgtcgcca
    10141 ttctgctatc gctgctgatt tttatcggcg aagcggtacg cgacgccttt gatcctgcta
    10201 aggcggtata agatgacatc tccattgctt gcgattgaaa atttatcggt aggtttccgt
    10261 cagcaacagc acgtgcgccc tgtcgttaac gccatttcgt tacaggtgaa cgccggggaa
    10321 acgctggcgc tggtcggcga gtcagggtca ggaaaaagcg tgacggcgct ttccattctg
    10381 cgtcttttgc ctacccctcc cgccgtctac ctctccggcg atattcgctt tcacggcgaa
    10441 tcattgcttc atgccagcga gcagacgcta cgcggcgtac gcggcaataa aatcgccatg
    10501 atttttcagg aaccgatggt ttcacttaac ccactgcata cgctggaaaa acagctctat
    10561 gaagtgctgt cgctccatcg gggaatgcgt cgggaggcgg caagggcgga gatgatcggt
    10621 tgtctggatc gggtcggtat ccgccaggcg agccagcgtc tgcgcgatta tccgcatcag
    10681 ctttccggcg gcgaacgcca gcgcgtcatg atagccatgg cgctgttaac acggccggaa
    10741 ttactgatcg ccgatgagcc gaccaccgcc ctcgacgtct ccgtacaggc gcagatctta
    10801 tctctactgc gggaactcca gcgtgagctc aatatgggat tgctgtttat cacccataac
    10861 ctcagcattg taaaaaaact ggcggattca gtggcggtaa tgcaacacgg caagtgcgta
    10921 gagaaccaac gcgccgacac gctgctctcc gcgccgaccc atccgtacac gcaaaaacta
    10981 ctcaacagcg aacccactgg cgatccggtt ccgctccccg ccgggcaggc gccgttgctg
    11041 gaagtggaca agctgcgcgt cgccttccca atccgcaaag gcattctgaa gcgcgtcgtg
    11101 gatcataatg tggtggttaa caatatcagt ttcaccctgc atccaggcga aacgctgggt
    11161 ctggtcggcg agtcaggatc gggaaaaagc accaccggtc tggcgctgtt acggcttatc
    11221 cgctccgaag gccgcatcgt gtttgacggt caatcgctgg atacgttaaa ccgccgccag
    11281 cttttacctg ttcgccaccg tatccaggtc gtattccagg acccgaactc atcgctaaac
    11341 ccgcgtttaa acgtattgca aattatcgaa gaaggcctgc gcgtccacca gcctacgctt
    11401 tcaggcgcgc agcgcgaaca gcaggtgaaa gcggtcatga tggaagtcgg cctggacccg
    11461 gaaacgcggc atcgttaccc cgctgagttt tccggcggcc agcgtcaacg tatcgccgtc
    11521 gccagggcgc tgattttaaa accgtcgctt attattctgg atgaaccgac ctcatcgctg
    11581 gataaaaccg ttcaggcgca gattcttgcc ctcctgaaat cgctccagca aaagcaccgt
    11641 ctggcctata tcttcattag ccacgatctg catgtagtac gcgcgctgtg ccatcaggtt
    11701 atcgtgctgc gacaggggga ggtggttgaa caggggcaat gcgagcgcgt gtttaccgca
    11761 ccgcaacaag cgtatacgcg tcagctactc gcgttaagct gacgcctaaa aaggattatt
    11821 gttagaaaaa ggttccgcta tcgccacgcc gaaatttttc agccgacagg tggcggcaaa
    11881 ctcatcctga cgattaacga acaggcacgg ttccccttcg cactccagca cggagcaagg
    11941 aacttcaata tcgcttagcg cctggctgag cttatgcatc actgaccacg cgctatcgcc
    12001 tgccggactc aacagtttaa gcgccaccag actattctcg gtgctctgcc cgttttgcgg
    12061 aatcggttca acctttgacc ccgcaaaacc cgccgaccag cgatagtttt gcggcagacg
    12121 gtgaacaatt gagagctgta atgtattcac tttctttcct cggaagcaca attacttcac
    12181 aatttactta catttatatt aacacatcat tgacaacccg tccttaaaca gattgctaac
    12241 gcccttctct ccgtcagtgg ctctacagca agcgggagtt aaaatagttt taccgacgcg
    12301 gagatagcgg cgggctatat gtacccgttt ctgcgatcta actcaacctt tttaactaca
    12361 atgatgtgac tttttacata aatggatttt acataaaata aacataaagg aggaaaatga
    12421 tgaattggta attgatatac atcaactatg aaagccgttt ggctttgcca tcgtgtagcg
    12481 gatagcgccc cccaacgccg cctgcgcatt cttcggcgcc attgagggac accgcgcccg
    12541 tcaccgtttt ttgggacggc tggcgtagag ataaaacaga atggaacagg cggcgcaaag
    12601 cgcaatcgac cagatcatcg gccacgcact gttaaaggta gccagcgaca gcaacgcgcc
    12661 gacgatagcg ccaataccaa agcggaaagt gcccgccaac gaagacgccg ttccggccat
    12721 atgcggaaac tcatccaaaa tgaccgccat cgcattggac gaaaccatcg acacacagcc
    12781 gacaaacgcc gcaacgccaa ccaccagcgc ccagaatcca atgcccatca gcgcgctgaa
    12841 aaccatccac accgccatcg caaactgaat ccatagcccg gcccgaaaca tgtttagcgc
    12901 ccctacccgt ctgacaaaac ggctgttgat aatcgtcatc acaaacagaa atacgatgtt
    12961 caacgcgaag tagtagccga aatcctgcgg cggaacatga ttaatttcga tatagacaaa
    13021 cggccccgcg ctcaaaaaag agaacatacc ggcaaaactg aacccgctcg ccagcatata
    13081 gctcagtacg cgtttgtggc gaaacaacgc ggcaaagtta cctattgtgg tacgaatatg
    13141 aaaaggctga cgccgctcaa cgggcagcgt ctctttaatc aaagcaaaga tcatgactga
    13201 cgccagaatc gccgcaatag ccagtatcca gaagatatag tgccagctta accataccaa
    13261 cacccagccg ccaacaatgg gcgccattaa cggcgctatc gtagtgacca gcatgacaaa
    13321 tgacatcatg cgcgaaaact cttcctttgg ataaatatcc cgcatcagcg cattgatgac
    13381 gacgcttgcc gccgcagcca ccaaaccgtg aaagaaacgc atcacgatca gttgatcgat
    13441 agtctgcgcc aacgcacagg cgaccgccgc agcggcaaat accagcgtcc cgcccaggat
    13501 gaccggctta cgcccgaggc tatccgccat cggtccatag ataagctgac ccagcgcaaa
    13561 ccccagaata taggtgctga gcgtcatctg cgcgctaccg gcaggcacgc cgaattgcgc
    13621 agaaatcacc ggcagcgctg gaagatacat atcaatcgac agcggcatta acatggccaa
    13681 caggccaaga ataaagacaa tggcaaagga agagtgctgc cgggtggtca catcgaactc
    13741 ctgaatttaa cgagatagtt agccgacgct ggcgatttct tcttcagtca acgggcggta
    13801 ctcgccggga gccagattct catccagcgt aatggcgcca atccgttcgc ggtgcagttc
    13861 cacaacgcga ttgcctactg cggcaaacat ccgcttcacc tgatgataac ggccttcgct
    13921 gatggtcaga cggacctgca caggtgttat cacctccagc gtagcgggtt tagtgagatc
    13981 tttttcatta tgcaactgca cgcctttcgc aaattgcgct gccgtatcgt cggccaccgg
    14041 cgactccagg gtcaccagat aggttttttc acagtgatgg cgcggcgacg taatgcggtg
    14101 cgaccactga ccgtcatctg tcattaacac cagaccggta gtatcgatat ccagacgtcc
    14161 tgcggcatgc agcttatacg ccaccggctc atccaggaaa tacagcaccg ttggatgatc
    14221 gggatcatcg gttgaacaaa cgtatccctg cggcttgtta agcataaaat agcgtggccc
    14281 gtgttgctgc gctaagggat tgccgtcata cgcaaccgca tgttccggga gcagtttgaa
    14341 ggccgcattt ttaatgatgt cgccatcgac ggtaacgcgg ttaccacgaa tttcacgccc
    14401 ggcaatagcg cggctgacgc caagctgctg agcgataaat ttatcaagtc gcatgtgtgt
    14461 gatttagcct gtaataatac ggaaatcggg cattctaccc gaaaaaaggg aattgctatc
    14521 cgctcagtat agcgggctaa ctatatccct caagggaaat gattcatggc atactattcc
    14581 cggaaccgtt taacgtagtg agaccatgat ttttacactc cgcccctacc agcaagaagc
    14641 cgtagacgcc acgctcagcc actttcgccg ccaccgtacg cccgccgtga ttgttctgcc
    14701 gaccggcgca ggtaaaagcc tggtgatcgc cgaactggcg cgcgtcgccc gcggacgggt
    14761 actggtgctg gcgcatgtga aagagctggt cgcgcagaac cacgccaaat attgcgcgct
    14821 ggggctggaa gcggatattt tcgccgccgg actcaaacgt aaagagagtc agggcaaagt
    14881 cgtgttcggc agcgtacagt cggtggcgcg taatcttgac gccttccagg aggagttttc
    14941 gctgttgatt gtcgatgaat gccaccgcat cggtgacgat gaagacagtc agtatcagca
    15001 aatcctcact cacctgagta aagttaatcc tcacttacgt ctgcttggac tcaccgccac
    15061 gccttttcgc ctcggaaaag gctggattta tcaatttcat tatcacggta tggtgcgcgg
    15121 caacgacaac gctctgtttc gcgactgtat ttatgaactg ccgctgcgct atatgattaa
    15181 acacggctat ctgacgccgc ctgagcggct tgatatgcca gtggtccaat acgatttcag
    15241 ccgcctgcag gcccaaagca atgggctgtt cagcgaagcc gacctgaacc gcgagctgaa
    15301 aaagcagcag cggattacgc cgcacatcat cagccagatt atggaatttg cgcaaacgcg
    15361 caaaggcgtg atgattttcg ccgccacggt cgaacatgcg aaagagattg tcggtctgct
    15421 tccggcggac gacgcggcgc tgattaccgg cgatacgcca gggcccgagc gcgacgcgct
    15481 gattgataat ttcaaggcgc agcgttttcg ctatctggtt aacgtctcgg tactgaccac
    15541 cggctttgac gccccacacg ttgatctcat cgcgattcta cgtcccacgg agtcagttag
    15601 tctttaccaa caaattgtcg ggcgtggtct gcgccttgcg ccgggaaaga ccgattgcct
    15661 gattcttgat tacgcaggca acccgcacga cctgtatgcc ccggaggtcg gtagcccgaa
    15721 gggaaaaagc gataacgtcc ctgtccaggt attttgcccg gcctgcggct ttgccaacac
    15781 cttctggggg aaaaccactg ccgacggcac gctgattgaa cactttggcc gtcgctgcca
    15841 gggctggttt gaggatgacg acggccatcg cgagcagtgc gattttcgct ttcgcttcaa
    15901 aaactgcccg cagtgtaatg ccgaaaacga tattgccgcc cgacgctgcc gggaatgtga
    15961 cgccattctg gtcgacccgg acgatatgtt aaaagcggcg ctcaggctca aggatgcgtt
    16021 agtcctgcgc tgtagcggaa tgacgatgca gcatgggcag gatgagaaag gcgaatggct
    16081 gaaaatcact tactatgacg aggacggcgc ggatgtcagt gagcgcttcc gcttgcacac
    16141 gcccgcccag cgtaccgctt tcgaacagct atttattcgc ccgcatacgc gcacgcccgg
    16201 cgttccttta cgctggatca cggcggcgga tattgtcgcg cagcaggcgc tgttgcggca
    16261 tcccgatttt gtggtcgcgc ggatgaaagg ccagtactgg caggtgcgtg aaaaagtgtt
    16321 cgactatgaa ggccgcttcc gccgggcgca cgaattacgt ggttaattgt acttttcatt
    16381 gatgtaacgg cgatttgagt atagaatccc gcccgccttt gcatacgcaa agcagatcac
    16441 ttacctgttg ctgggtcgcc tgtagcagga attattaaag agagatttaa atgtttacta
    16501 tcaacgcaga agtacgtaaa gagcagggta agggtgcgag ccgccgcctg cgcgccgcta
    16561 acaagttccc ggcaatcatc tacggcggtt ctgaagcccc gattgctatc gaactggacc
    16621 acgaccaggt gatgaacatg caagctaaag ctgaattcta cagcgaagtt ctgaccctcg
    16681 ttgttgacgg taaagaagta aaagttaaag ctcaggctgt acagcgtcac gcttacaaac
    16741 cgaagctgac tcacatcgac ttcgttcgcg cgtaatcgcc tggaagttga agaaaaaccc
    16801 cgccccggcg gggttttttt atgcgtttaa ttgaatttga cgacatgcag agcaacgaga
    16861 acccactttg cttttctgct ttcttacacc tcgccacatt caattagcgc ctcccctaat
    16921 cgaggatctg tagtttccgc cgcggtattc atacctttaa gccgattgaa taatgcccgt
    16981 tgacgaacgc tggcactttc cggtttccat ggcaaaattc gtattggtat cgtttgccca
    17041 tcattcaacg catcaaatac cttttcattg gtcagtaagt cgccgcagct ccatgtcttg
    17101 ctatcaaact gaaaatcaaa taagacatgg agttccagtt catctacacg cacttgacgc
    17161 tttgcattat cgatgcgtat ttccaccttc tctttatgcg tcaaagttgc atcaagattg
    17221 agtccatacc gtttcaactg ccccttgtcg taatagtaac gtatgctgga ccaggttgat
    17281 ttaaaagcaa atccagtaat gaataaacca cttaacaaga acagcgggca tatgaacaag
    17341 ctcagtaacc agttggcgcc ataagtataa aacagtacca acgagagaac ggtgaacacc
    17401 atgccgagca tcaacatcat caaaaatgcg acaatgtgcg catacaaaac ctgccgaaat
    17461 aaactgaaat taacaggcgg cctctgacgt attcctttac tcactacggc gtccttttat
    17521 gtcgtatgcc tttatttccc gcccgacgtg cgtcgctgca actgatcgcg caaattcggc
    17581 ggcgtccctt tgatagtcag ggtatcggtc gccgggtccc agaaaatccg ctcgcccagt
    17641 agcatcgcat caaagttaat cgttaacccg ccgccgctgc cggcatattt ggttaactgg
    17701 cgtagcgtac tgcgatctgc cgggaagctc tcttccagct catagccttt ttcggcggta
    17761 aattcgctga agctgacttc actgacgccg gaaagctctt tagacagcga ttccagctca
    17821 atctcttccc cggcttgtaa ctgctcgttg cagtagctgt acacctgctg acgcacgttc
    17881 tgacgttctg ctttatccaa ctgcgcttct gcggtgaaat catccactgc ctgcaacagg
    17941 ccgcgattct gcgctttggc gttcaaccct tcgctggcgc cgaggaaatc cataaagaag
    18001 tcagcgacct tgcgccctac ccgacctttc aggaacgtca ggtagcgggt cgattgcgga
    18061 ttagtttccc actcggtaag atcgatacgc gccacgatat ccgcatggtt gatatcaaga
    18121 taatgcgtcg ggttaatgtc cagattttca ttgacccgca tactgctcag gttgttcagt
    18181 accgtaacca gcagatactc caccgccagg taacgataat ggcagaacaa tacaatgccg
    18241 ccgtccgcaa agggatattt cgccagttcg tcacgcaggc gtccggtcgc cgcccggcta
    18301 aaggcaagaa aatcttcttc cccctgacgt tgcaaccgca gcgcttgcgc cagttcactc
    18361 tcttcattaa acaggccata cgccttattc ttggcgctat agacccgatg cagttcagcc
    18421 accatctcga caacggtggt tgtcggctcc agcaatgaat cgcgcaagac cagctcaaga
    18481 ttttgctcat cgcgcttgat aagctggtgc agggcaatct ggttgatatc cagactcatg
    18541 ataaactctc ctttaagacc gggcggtatt caaccaccgc ctgccggaag acgcaagcaa
    18601 tcgccctgtc atttcaggcg ttatccgtaa cgcgaatgat ttaggggata aaaatgcaga
    18661 aaaaaaactg ttgctacggt aatatgttgc cctttcatga acaaacagat tttgatttat
    18721 gccacaactc tcccgctata gtgatgaaca tgttgaacaa ctgctgagcg aactgctcag
    18781 tgtactggaa aaacataagg cgccgaccga tctttccctg atggtactgg gaaatatggt
    18841 caccaacctt atcaacacca gcgtggcgcc ggctcaacgc caggcgattg cgaactcttt
    18901 tgcccgcgcc ttgcagtctt cgattagcga agacaacgcg cactaaaaag ccgactccgg
    18961 agaaacaagc gacaggtatg gtaactcatc gtcagcgcta ccgtgaaaaa gtctcccaga
    19021 tggttagctg ggggcactgg ttcgctctgt tcaatatact gttggctacg ttgctcggca
    19081 gccgttacct gtttgtcgcc gactggccga caacgcttgc gggtcgcata tactcctacc
    19141 tgagcattgt cgggcacttt agctttctgg tgttcgccac ctatttgctt attctttttc
    19201 cgctcacgtt tatcgtgatg tcccagcggc tgatgcggtt tttatcagcc attctggcga
    19261 ccgcgggtat gacgttgttg cttatcgaca gcgaagtctt tacccgtttt cacctgcatc
    19321 ttaaccccat tgtctgggaa ctggtcatca accctgacca gaacgaaatg gcgcgcgact
    19381 ggcagcttat gtttattagc gtgccagtta tcttattgat tgagatgcta tttgcgacat
    19441 ggagttggca aaagctgcgc agtctcacgc gccgccgcca tttcgcaagg ccgcttgcgg
    19501 cattcttttt cgtctccttt atcgcatcgc atcttatcta catctgggca gacgctaatt
    19561 tttaccggcc gattaccatg cagcgggcaa acctgccgct ctcttatccg atgacggcgc
    19621 gacgttttct tgaaaaacac ggtctgctgg atgcgcagga atatcagcgc cgtctggtag
    19681 agcaaggcaa tccggaagcg gtctccgttc agtacccgct cagcaatttg cactatcgcg
    19741 atatgggcac cggtcagaat gtgctgctca ttaccgtaga cggcctgaac tattctcgct
    19801 ttgagaagca gatgccggag ctggctacat ttgccgagca aaacatcgac ttcacccgtc
    19861 atatgagttc agggaatacc actgataacg gtattttcgg cctgttctat ggcatatcgc
    19921 caggctatat ggatggcgtg ttatccacca gaacgcctgc ggcgctcatt accgcgttga
    19981 atcagcaagg ctaccaactg ggactgtttt cttcggatgg cttcgccagc ccgctttatc
    20041 gtcaggcatt actgtccgat ttctcgatgc cggcagcgca aacgcagtct gatgcgcaaa
    20101 cggccagcca gtggatagac tggcttgggc gctacgcaca ggaagataac cgctggttct
    20161 catggatatc gtttaacggt actaacattg atgacagtaa ccagaaaaat tttgttaagc
    20221 gttacgccag tgccgccagc gacgtggatg cgcaaatcaa tcgggttctg aacgcgctgc
    20281 gagaggccgg taaattcgac aatactgtcg tgatcattac cgcaggacgc ggcataccgt
    20341 tgacgccgga agaaaatcgc ttcgactggt cgcaaggtca tctgcaagta ccgctggtga
    20401 tccactggcc ggggacgcct gcgcagcgta ttaatgtgct taccgatcat accgatgtga
    20461 tgaccacgtt gatgcaacgc ctgttacatg tcagcacgcc agcgaacgaa tattcacagg
    20521 gccaggacat ctttaccgtt ccacgtcgtc ataactgggt aacggcggca gacggcagta
    20581 cgctggcaat cacgacgccg caaatgaccc tggtgctcaa taataacggt cattatcaga
    20641 cctatgactt acacggcgag aagatcaaag atcagaagcc gcagctcagt ctgctgctgc
    20701 aagtgctaac agaagagaaa cgttttatcg ctaactgatt aattataaat cagttagcac
    20761 cgtttcccct tgcattcgcg ttggaaagag gtagtattag cacccacaag tcggcacgta
    20821 gcgcagcctg gtagcgcacc gtcatggggt gtcgggggtc ggaggttcaa atcctctcgt
    20881 gccgaccaaa attcccctta aaagccagcc tgccagggct ggttttttta tatatccaat
    20941 ttgcaaatgg tgaaatgatg gtgaaatagc tatcgaaggt cactgcaaat tgacttcaag
    21001 ctccctccaa cgcgaaaagt tgaacagatg acttaaatac attgattagt catccttaac
    21061 cagtagaatc cgccacgact ggtaactatt caatacacgc actatcgaac gatcgccagt
    21121 ttgccgcagc ccgttcttgc atacaatgtg gctgcggcac accatcacat cagaaatttg
    21181 aaaatcaggg taaacctgtc acttaacctg aagcaggtct tcatagcggg tggtatatcg
    21241 ggatgacagt atgtttctct tcatagccca ctgttgctgg ataccctccc cggcaaagta
    21301 cagctttccc ctgcccttct ttgcattcag gtgatccagt acttccatcg gcttctcgct
    21361 accggcgcgc ggcgcgttat catcgaaaaa gttgcgccgc gccctgactg aagaagtctc
    21421 ccctatttca cctgtacatc atccgtactg tctgatgttg ttcgtccggg aatatctttg
    21481 tcgcaccgca cctcattcac ctggtgcatc agttacgacg ccactgaacg ttcagatagc
    21541 tccccagcat ctcctccaca agaggtcgca ggccatccaa aaatgtcttt ttcgcgctct
    21601 ccatcgctct tgctccgata gtgcgctctg catcggtatt accgaccagc ccagacggtc
    21661 tcagctctgt gtcagacagc atccggtacg tttcctcata atccgatatt tgcttttcac
    21721 gaagcgcgtt aacgcgtttc ggcgctttgc gctccagcac tctgtgtaac ggcccccact
    21781 gcagtatcca ctccctgaac tcgctttttt cagcggcttt cacctgaagc tccgcgtcct
    21841 gaaggtctgt aaccgtcacg ccggatacgt caaagaaacg catttctgac gtcacgctgg
    21901 tcagcccgag tgatttcttc agcttattct gatacgccag ccagacctca atttcatcaa
    21961 cgagagccag cgttctgacc ttttcccggg caatctgttc cagttttccc agacggaaca
    22021 tctcacgccc cgtggcaacc agcgccgcga gatcgttatc gtattgccct ttttctgcat
    22081 tatgtaccag ctgtacgttc ttcatctggt gcaaaaaaaa tgtgacccgg tcctcgcagc
    22141 ttgaggttgc ctctgttgcc atagcaaagg tgtttgctct caacgcctca tcttcagcca
    22201 gttgtgccag ccaggacgat atctgtgcct taaaccccgc gtcctttatg aagttttccg
    22261 tctcactcag tctgtccagg aagaggctga aggcgtcggc gttatcttcc tgtccgaaca
    22321 tatgccatct gtctgcagga gccggttccc cctcccgggc aggcaccagc cagtcagcgg
    22381 ccgccaggtg cagtgcccga gtttcccggg gggcggaggc tcccgccata tcgaatcgta
    22441 ttatggggcc tgaatagcca ggcgcgctgg tgatctcccg cagcgcctgc aaagtacgtt
    22501 cagacagtgg gttcccttcc agatttacgg ttgtctctga agacagatga atgagacttt
    22561 ccggcaggcg ggtcagctgg ttacgataga ccgacagcga cagtagtcct gacggcagca
    22621 tcggcaggct ggtcagccgg ttaccagata ccatcagctc cttcagttct gacggcagca
    22681 ccggcagact ggtcagccgg ttaccagata caatcagctc cttcagtcct gacggcaacg
    22741 ccggcaggct ggtcagccga ttattatagg cccacagctt atataattct gacggcagcg
    22801 tcggcaagct ggccagttgg ttatcagata ccgacagctc ctgtagccct gacggcaacg
    22861 tcggcaggct ggtcagctgg ttattatagg cccacagctt acataattct gacggcagcg
    22921 ccggcaggct ggccagttgg ttatcagata ccgacagctc ctgtagccct ggcggcaaca
    22981 ccggcaggct ggtcagttga ttaccaaaga tccacagctt acatagtcct gacggcagcg
    23041 ccggcaggtg ggtcagcggg ttactaaaga tcgacagttc cagtagtcct ggcggcagca
    23101 ccggcaggct agtcagctgg ttaccagaga cctccagcgt ccgcagttct ggcggcagcg
    23161 ccggcaggct ggtcagatta ttatcaggaa taaccagtgt ggtaatatgc gcgggtaaac
    23221 agtctggcaa ggtggtaaga cctgattctc ccacgttaag cactgcattg ccattattca
    23281 ggcaggcacg cattttctgt accgctgctg cacggccgcg tgactcttct gcgggtgcag
    23341 cccttctcca cgctgaccag acagcatcat actctgctgg cgtctgtgga gccgttgtgg
    23401 cagggaggaa ggatgtcctg aatgtcccgg atgccccttc cgcgtgtcct gtgccctcct
    23461 caccctgtgc tgtgtccagg gtgaggcgat gtgtttcact gtacccctgg caatttacgg
    23521 tatagttccc ggcatcatca agggtgactg acaatatctc ctgactgtct tcatccagaa
    23581 tacagaagta attttccccg tgctggccgg aatgaatgct ttcctcccat ccggcatacg
    23641 cgagcgtcct gagcagttca aatctgttga tcacatcctc ccgcgtcgtt ccggccggcg
    23701 ggtgacaaat cgtccagatg cactccagcg cttcagtctg gtgcgttgag caaaaaaatt
    23761 ccttcatttt ttcccaggaa ctcatttcag ggggggtatc agaccaggca atacgataaa
    23821 tgcggcgatt actgatggtg gcgggaagac atccgcttcc aatatgaaag ggcataacaa
    23881 aaaaccttta taaatttaca tatagtatct gtccggcaga catcatctct tcctggtctt
    23941 aatttcacaa taaggttatc ggcggattca tggtcgtcct gacatggcgg gcttcagaag
    24001 gtgcagaaga aaaatccgtt atgatgaccg gatggcggga ctgtcatttt acagctaaag
    24061 tgtcgatttt ttcagggtcg ctttccacga tgaccagatc atccggtatc aacgcccggg
    24121 cgttcaattt tcgattctgc ctgcctgcgc agctcttccg gcgaataaac cctttgaacg
    24181 actttaccgt ctttaaactg ccagcagcat gaatatcagc gcgacggttt tcatccgtat
    24241 caggcaactc tgcaacgctc tggccagcag gccacagccc ggaaacatca cgcgtaatac
    24301 acgtaataac atcgttatcg tcgtaggtaa ttttcagcgt gtctgctgaa aataattgct
    24361 ggcacccata ccagtcctga ccatcctctg atttaagata cgccgcatcg gcgaataatg
    24421 tgtcatctgg ttccggtgca tacggaatga aatttttaat atttaaaaac tgtttgttct
    24481 ttttattttt tttccgctgt cataattatt ccttcttata cacttggggc tgtcacccac
    24541 gtatcaccaa ccagatactg aatgggacgt tgtcacccga atagtcatcg cgccacgcac
    24601 tcccattacc tcaatcactg cgccagcgag acagatatta ccgcagccag tatccgtgat
    24661 gattttgtta taagcgtaag accaggagcc acgacacatc cagtaagggt gattgaatgc
    24721 gccctgagac tccagccaga cgataaactc cgccgtcgtc cacggattat catcacagcc
    24781 gataataact gcgccatcaa acgctcgcgc ggcaccgata cgacgcacaa acaaatcctt
    24841 gtccggaata tcgccgccat tctgtgattt ttgtaatgca tcggcggcac gacttatggt
    24901 ttctcgcaaa ccaacgtatt cgataagacc gtcaacgctt tttcctgaca gcgccgtcag
    24961 ggtttcgtcc agcggctgct tgcccgccag tttattcagt accgtggtgg caaagttcgg
    25021 atcatttccc aacgcgtcag ccagttcctg cagggtgtcc agtggctcca gtacggaacc
    25081 aaccagcgcg gcaatcagtt tgcggacaaa ctccgcgttt gttgtctgaa gccctttagc
    25141 atcgcctggc ggcgtcggtg tggtcggcgt tccagtgaat gccgggctgt ccagcggcgc
    25201 tttggtccgt acctcaccca taacggtttt taccgccttt ggtgtggccg ccagcgcttc
    25261 gctgtcactg tccgtggcac tgcttaattt aacgatacct tttttcgtca ggcttgcatc
    25321 ttccagggaa atcacgtctg cgatatcctc ggcccgtttc gcggcctctt cggctctggt
    25381 tgccgattct ccggctgcag ctctgctttg cgctgccagt gatgcgctgg tatcagatgc
    25441 ggcggcgtgg gtggatgcct acgatgctga tgacgaggcg gctgccgccg ttctggctgt
    25501 gtcagccgac gccgcgctgg ctgatgcctc cccggctttt gtggtcgccg tacctgcgct
    25561 gctctccgca gatgctgcgg atgaagctgc cgaccaaaat tccccttgaa aaccagcctg
    25621 tcagggctgg tttttttatg cctacaatta aaaagttagc tgatgccaga gacgttattt
    25681 tgcatgaact gattttgcat gaactgattg gacatctttc ctgtgcagtg gtcacagtaa
    25741 agtcaatgca ggcaactaac gtaaaccatg tttgtactaa aacagaaaaa gcgcatctac
    25801 accctatact ggaaaaaatg tttgcagtgg caggtaaatg agtaagcaat ctgtcgcagc
    25861 aataataaaa cgttctggta aggtaaacgg cctaccacgc ctttgtcgct aacaattagc
    25921 ctccctgtcg ccatagggtc gataacgatc ggctattcac aacacgtttt gtagacaacg
    25981 tacggtgatt aattactcct tcagccagca actcgctaat tgttattcaa cttcagaaat
    26041 tataactaat tgaagcacct acaaaattat gccctgaatt tttatccgta agtgatccat
    26101 tcgagaaatg ccggatataa gcttctgtag aaaaagcccc aaagttccag ccaagaaacg
    26161 ctttttctcc aaaggtaaat gcagaattga cacgcatatc atctcgcgac ttagatttta
    26221 tataagcccc cagaccaata ccggtataga taccagcgaa atgaaccagc gccacatcct
    26281 tcgagatacc caatacgccc tggttatatt tattacaggg aacgctgcca gaatgtttac
    26341 tgcaatcatc gctaccctta gccttaaatc ctcctaactc cagattattt cttgcctgta
    26401 aaaagaaaaa atcgctgggt tcactgtatg tcagaaaagc cgtatataag tgctcaaccc
    26461 ctcctcttct tatactttct cccgcagcaa aagagatctg atgcttgttg cccttgccaa
    26521 aaaaacatta tcattagcag aacatgcgaa tgcacaaggt aataatagat atataaatat
    26581 tctcttcata tacactccac caccatttca atgtcaatag ttatttttaa ccggctaaca
    26641 tatttaaaat tttctacgcc acgcttacgc tcacagaaac ggctgatata gcatccacac
    26701 tacgttctcc ccttgagtcg ccccaacggg tgctcaaaac gccgcgagtg
//
LOCUS       DAJVKX010000053        26466 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000053 DAJVKX010000000
VERSION     DAJVKX010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26466
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.053"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            275..829
                     /locus_tag="OPY25_002305"
     CDS             275..829
                     /locus_tag="OPY25_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCS0927907.1"
                     /translation="MSDTLRPYKDLFPEIGQRVMIDTSSVVIGDVRLADDVGIWPLVV
                     IRGDVNYVAIGARTNIQDGSVLHVTHKSPSNPHGNPLIIGEDVTVGHKVMLHGCTIGN
                     RVLVGMGSIVLDGAIIEDDVMIGAGSLVPQHKRLESGYLYLGSPVKQIRPLSDAERSG
                     LQYSANNYVKWKDDYLSQDNHIQP"
     gene            complement(805..1062)
                     /locus_tag="OPY25_002306"
     CDS             complement(805..1062)
                     /locus_tag="OPY25_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HCS0927908.1"
                     /translation="MNQAIQFPDREEWDTAASAIIFPALVNGMQITCAIKKDVLAYRF
                     GGETAEQWLAIFREYRWDLEEEAEALILAQQEDDHGWIWLS"
     gene            complement(1059..1877)
                     /gene="aroE"
                     /locus_tag="OPY25_002307"
     CDS             complement(1059..1877)
                     /gene="aroE"
                     /locus_tag="OPY25_002307"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCS0927909.1"
                     /translation="MEAYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFI
                     NTLDAFFAAGGKGANITVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTD
                     GIGLLSDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAK
                     IFAHTGSVHAMDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKG
                     NTPFLSWCVQQGAKRYADGLGMLVGQAAHAVLLWHGVLPQVEPVIKLLQQELLA"
     gene            complement(1882..2454)
                     /gene="tsaC"
                     /locus_tag="OPY25_002308"
     CDS             complement(1882..2454)
                     /gene="tsaC"
                     /locus_tag="OPY25_002308"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HCS0927910.1"
                     /translation="MNNNLPTGSSAAVVDLLNKENVIAYPTEAVFGVGCDPDSETAVT
                     RLLALKQRPVDKGLILIAASFEQLKPYIDDSILTAAQRKAVFDCWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTNHPLVVALCNAYGKPLVSTSANLSGLPPCRTVEEVRAQFGD
                     DFPVVEGATGGRLNPSEIRDALTGELFRQG"
     gene            complement(2459..3001)
                     /locus_tag="OPY25_002309"
     CDS             complement(2459..3001)
                     /locus_tag="OPY25_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HCS0927911.1"
                     /translation="MAKSALFSVRKNEPCPQCGAELVIRSGKHGPFLGCSRYPECDYV
                     RPLKSQADGHIVKILEGQLCPECGAVLVLRQGRFGMFIGCSQYPQCEHTVVIDKPDET
                     AIACPACQQGHLVQRRSRYGKIFHSCDRYPECQFVINFTPVAGECPECHYSLLIEKKT
                     AQGVKRFCASKQCGKPVPVE"
     gene            complement(3028..3501)
                     /locus_tag="OPY25_002310"
     CDS             complement(3028..3501)
                     /locus_tag="OPY25_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HCS0927912.1"
                     /translation="MFDVLMYLFETYIHNEAELRVDQDRLERDLTDAGFDREDIYNAL
                     LWLEKLADYQDGLAEPMQLASDPLSMRIYTVEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            complement(3473..4597)
                     /gene="dprA"
                     /locus_tag="OPY25_002311"
     CDS             complement(3473..4597)
                     /gene="dprA"
                     /locus_tag="OPY25_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCS0927913.1"
                     /translation="MARTEIWLRLMYVGDLYGEAMLNMANSLIRQPQINRTHLQEAGL
                     TARQAERFLQLPAGVLDETLRWLELPQHHFLCADSEIYPPQLRAIDDYPGAIFIDGDP
                     ACLHTCQLAVVGSRSHSWYGERWGRLLCESLAKSGLTITSGLARGIDGVAHNAAMSMG
                     GKSVAVLGNGLAKIYPRRHAMLAENLIATGGAVVSEFPLSTPPLSQNFPRRNRIISGL
                     SKGVLVIEAALRSGSLVTARCALEQGRDVFALPGPIGSPGSEGTHWLIKQGATLVTTP
                     EDILENLQYGLHWLPTTAENSLYSLNQDEAALPFPELLANVGDEVTPVDVVAERAGQP
                     VPAVVAQLLELELAGWIAAVPGGYVRLRRASHVRRTNVFV"
     gene            4729..5238
                     /gene="def"
                     /locus_tag="OPY25_002312"
     CDS             4729..5238
                     /gene="def"
                     /locus_tag="OPY25_002312"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCS0927914.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRNGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVE
                     KLDRLNARA"
     gene            5254..6201
                     /gene="fmt"
                     /locus_tag="OPY25_002313"
     CDS             5254..6201
                     /gene="fmt"
                     /locus_tag="OPY25_002313"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCS0927915.1"
                     /translation="MSDSLRIIFAGTPDFAARHLDALLTSGHNIVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPIT
                     AEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVA
                     TGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA"
     gene            6253..7542
                     /gene="rsmB"
                     /locus_tag="OPY25_002314"
     CDS             6253..7542
                     /gene="rsmB"
                     /locus_tag="OPY25_002314"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCS0927916.1"
                     /translation="MKKQNNLRSLAAQAVELVVEQGQSLSNVLPPLQQKVADKDKALL
                     QELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAET
                     VEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQ
                     WQRIIEANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVH
                     ALPGFAEGWVTVQDASAQGCAVFLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPAQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKAFLQR
                     TPDAALSETGTPDQPGQQNLPGGEEGDGFFYAKLIKK"
     gene            7564..8940
                     /gene="trkA"
                     /locus_tag="OPY25_002315"
     CDS             7564..8940
                     /gene="trkA"
                     /locus_tag="OPY25_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HCS0927917.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRSLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSEAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERDQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            9082..9495
                     /gene="mscL"
                     /locus_tag="OPY25_002316"
     CDS             9082..9495
                     /gene="mscL"
                     /locus_tag="OPY25_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCS0927918.1"
                     /translation="MSFIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAFTLREAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFVAIKLINRL
                     NRKKAEEPAAPPAPSKEEVLLGEIRDLLKEQNNRS"
     gene            complement(9431..9700)
                     /locus_tag="OPY25_002317"
     CDS             complement(9431..9700)
                     /locus_tag="OPY25_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor A"
                     /protein_id="HCS0927919.1"
                     /translation="MSRYQHKKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYLRKGK
                     HGNRGNWEASGKKVSDFFTTGLLLIKNGYFVLSADRGFRPITLPL"
     gene            complement(9759..10184)
                     /gene="zntR"
                     /locus_tag="OPY25_002318"
     CDS             complement(9759..10184)
                     /gene="zntR"
                     /locus_tag="OPY25_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HCS0927920.1"
                     /translation="MYRIGELAKLADVTPDTIRYYEKQQMMDHEVRTEGGFRLYTEND
                     LQRLKFIRYARQLGFTLESIRELLSIRIDPEHHTCQESKSIVQERLQEVEARIAELQT
                     MQRSLQRLNDACCGTAHSSVYCSILEALEQGASGAKSVC"
     gene            complement(10195..10563)
                     /locus_tag="OPY25_002319"
     CDS             complement(10195..10563)
                     /locus_tag="OPY25_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HCS0927921.1"
                     /translation="MWLLDQWAERHIIEAQRKGEFDNLPGRGEPLILDDDSHVPAELR
                     AGYRLLKNAGCLPPELEQRRDAIQLLDILNSIREDDPQYHQVSRQLSLLELKLRQAGL
                     STDFLHGEYAEKLLHKINDN"
     gene            complement(10670..11053)
                     /gene="rplQ"
                     /locus_tag="OPY25_002320"
     CDS             complement(10670..11053)
                     /gene="rplQ"
                     /locus_tag="OPY25_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCS0927922.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKTEAAAE"
     gene            complement(11094..12083)
                     /gene="rpoA"
                     /locus_tag="OPY25_002321"
     CDS             complement(11094..12083)
                     /gene="rpoA"
                     /locus_tag="OPY25_002321"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCS0927923.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            complement(12109..12729)
                     /gene="rpsD"
                     /locus_tag="OPY25_002322"
     CDS             complement(12109..12729)
                     /gene="rpsD"
                     /locus_tag="OPY25_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCS0927924.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIGQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTYKRKPERSDLSADINEHLIVELYSK"
     gene            complement(12763..13152)
                     /gene="rpsK"
                     /locus_tag="OPY25_002323"
     CDS             complement(12763..13152)
                     /gene="rpsK"
                     /locus_tag="OPY25_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCS0927925.1"
                     /translation="MAKAPVCARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            complement(13169..13525)
                     /gene="rpsM"
                     /locus_tag="OPY25_002324"
     CDS             complement(13169..13525)
                     /gene="rpsM"
                     /locus_tag="OPY25_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCS0927926.1"
                     /translation="MARIAGINIPDQKHAVIALTSIYGVGKTRSKAILAAAGIAENVK
                     ISELSEEQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPCKPIKK"
     gene            complement(13672..13788)
                     /gene="rpmJ"
                     /locus_tag="OPY25_002325"
     CDS             complement(13672..13788)
                     /gene="rpmJ"
                     /locus_tag="OPY25_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCS0927927.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            complement(13820..15151)
                     /gene="secY"
                     /locus_tag="OPY25_002326"
     CDS             complement(13820..15151)
                     /gene="secY"
                     /locus_tag="OPY25_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCS0927928.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVMNPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTHLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            complement(15159..15593)
                     /gene="rplO"
                     /locus_tag="OPY25_002327"
     CDS             complement(15159..15593)
                     /gene="rplO"
                     /locus_tag="OPY25_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCS0927929.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            complement(15597..15776)
                     /gene="rpmD"
                     /locus_tag="OPY25_002328"
     CDS             complement(15597..15776)
                     /gene="rpmD"
                     /locus_tag="OPY25_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCS0927930.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAV
                     RGMVNAVSFMVKVEE"
     gene            complement(15780..16283)
                     /gene="rpsE"
                     /locus_tag="OPY25_002329"
     CDS             complement(15780..16283)
                     /gene="rpsE"
                     /locus_tag="OPY25_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCS0927931.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            complement(16298..16651)
                     /gene="rplR"
                     /locus_tag="OPY25_002330"
     CDS             complement(16298..16651)
                     /gene="rplR"
                     /locus_tag="OPY25_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCS0927932.1"
                     /translation="MDKKSARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            complement(16661..17194)
                     /gene="rplF"
                     /locus_tag="OPY25_002331"
     CDS             complement(16661..17194)
                     /gene="rplF"
                     /locus_tag="OPY25_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCS0927933.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     VNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            complement(17207..17599)
                     /gene="rpsH"
                     /locus_tag="OPY25_002332"
     CDS             complement(17207..17599)
                     /gene="rpsH"
                     /locus_tag="OPY25_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCS0927934.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            complement(17633..17938)
                     /gene="rpsN"
                     /locus_tag="OPY25_002333"
     CDS             complement(17633..17938)
                     /gene="rpsN"
                     /locus_tag="OPY25_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCS0927935.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNATDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            complement(17953..18492)
                     /gene="rplE"
                     /locus_tag="OPY25_002334"
     CDS             complement(17953..18492)
                     /gene="rplE"
                     /locus_tag="OPY25_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCS0927936.1"
                     /translation="MAKLHDYYKDEVVNKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            complement(18507..18821)
                     /gene="rplX"
                     /locus_tag="OPY25_002335"
     CDS             complement(18507..18821)
                     /gene="rplX"
                     /locus_tag="OPY25_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCS0927937.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNTATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            complement(18832..19203)
                     /gene="rplN"
                     /locus_tag="OPY25_002336"
     CDS             complement(18832..19203)
                     /gene="rplN"
                     /locus_tag="OPY25_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCS0927938.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGP
                     VTRELRNEKFMKIISLAPEVL"
     gene            complement(19367..19621)
                     /gene="rpsQ"
                     /locus_tag="OPY25_002337"
     CDS             complement(19367..19621)
                     /gene="rpsQ"
                     /locus_tag="OPY25_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCS0927939.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKM
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            complement(19621..19812)
                     /gene="rpmC"
                     /locus_tag="OPY25_002338"
     CDS             complement(19621..19812)
                     /gene="rpmC"
                     /locus_tag="OPY25_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCS0927940.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLTEKAGA"
     gene            complement(19812..20222)
                     /gene="rplP"
                     /locus_tag="OPY25_002339"
     CDS             complement(19812..20222)
                     /gene="rplP"
                     /locus_tag="OPY25_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCS0927941.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAAGADVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            complement(20235..20936)
                     /gene="rpsC"
                     /locus_tag="OPY25_002340"
     CDS             complement(20235..20936)
                     /gene="rpsC"
                     /locus_tag="OPY25_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCS0927942.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            complement(20954..21286)
                     /gene="rplV"
                     /locus_tag="OPY25_002341"
     CDS             complement(20954..21286)
                     /gene="rplV"
                     /locus_tag="OPY25_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCS0927943.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            complement(21301..21579)
                     /gene="rpsS"
                     /locus_tag="OPY25_002342"
     CDS             complement(21301..21579)
                     /gene="rpsS"
                     /locus_tag="OPY25_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCS0927944.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVSDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            complement(21596..22417)
                     /gene="rplB"
                     /locus_tag="OPY25_002343"
     CDS             complement(21596..22417)
                     /gene="rplB"
                     /locus_tag="OPY25_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCS0927945.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            complement(22435..22737)
                     /gene="rplW"
                     /locus_tag="OPY25_002344"
     CDS             complement(22435..22737)
                     /gene="rplW"
                     /locus_tag="OPY25_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCS0927946.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKTNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            complement(22734..23339)
                     /gene="rplD"
                     /locus_tag="OPY25_002345"
     CDS             complement(22734..23339)
                     /gene="rplD"
                     /locus_tag="OPY25_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCS0927947.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            complement(23350..23979)
                     /gene="rplC"
                     /locus_tag="OPY25_002346"
     CDS             complement(23350..23979)
                     /gene="rplC"
                     /locus_tag="OPY25_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCS0927948.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA"
     gene            complement(24012..24323)
                     /gene="rpsJ"
                     /locus_tag="OPY25_002347"
     CDS             complement(24012..24323)
                     /gene="rpsJ"
                     /locus_tag="OPY25_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCS0927949.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            24703..25170
                     /gene="hopD"
                     /locus_tag="OPY25_002348"
     CDS             24703..25170
                     /gene="hopD"
                     /locus_tag="OPY25_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leader peptidase HopD"
                     /protein_id="HCS0927950.1"
                     /translation="MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYH
                     QICLPERLPDALWGAIAGYGGFALIYWGYRLRYQKEGLGYGDVKYLAALGAWHCWETL
                     PLLVFLAAMLACGRFGVALLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG"
     gene            complement(25167..25643)
                     /gene="bfr"
                     /locus_tag="OPY25_002349"
     CDS             complement(25167..25643)
                     /gene="bfr"
                     /locus_tag="OPY25_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HCS0927951.1"
                     /translation="MKGDVKIINYLNKLLGNELVAINQYFLHARMFKNWGLTRLNDVE
                     YHESIDEMKHADKYIERILFLEGIPNLQDLGKLGIGEDVEEMLRSDLRLELEGAKDLR
                     EAIAYADNVHDYVSRDMMIEILADEEGHIDWLETELDLIAKLGMQNYLQSQIKVTD"
     gene            complement(25716..25910)
                     /gene="bfd"
                     /locus_tag="OPY25_002350"
     CDS             complement(25716..25910)
                     /gene="bfd"
                     /locus_tag="OPY25_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HCS0927952.1"
                     /translation="MYVCLCNGISDKKIRQAVRQFHPQSFQQLRKFIPVGNQCGKCIR
                     AAREVMQDELTQMPEFKEIA"
     gene            complement(26095..>26466)
                     /gene="tuf"
                     /locus_tag="OPY25_002351"
     CDS             complement(26095..>26466)
                     /gene="tuf"
                     /locus_tag="OPY25_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCS0927953.1"
                     /translation="GENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKD
                     EGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL
                     RFAIREGGRTVGAGVVAKVLG"
BASE COUNT         6415 a         7020 c         6397 g         6634 t
ORIGIN      
        1 ctttcagagt caaccctgaa tttcaggatt tttctcttca accgaccggc tgtttgtgtg
       61 aagtgattca catccgccgt gtcgatggag gcgcattata gggatcccat ttttttgcac
      121 aagcgttttt tggatctttt ttctgtttgt tgatttttca tccctttcgc tccattcctg
      181 cgcaaagtgg cgattttttg atgctatctc cccttgcaca acgccgttaa agcaaccaaa
      241 gtcttcatga ctattcattt atgatgaggt agacatgtct gacacattac gtccttataa
      301 ggatcttttt cctgaaatcg gtcagcgcgt gatgatcgat accagcagcg tggttattgg
      361 cgatgtccgt ctggcggatg atgtcgggat ctggccgctt gtggtgattc gcggcgatgt
      421 gaattacgtt gcgatagggg ctcgtacgaa cattcaggat ggcagcgttc ttcacgtaac
      481 ccacaagtct ccatccaatc cacacggcaa cccattaatc attggcgaag atgttaccgt
      541 tggccataaa gttatgctgc acggctgtac catcggtaac cgcgtactgg tcggtatggg
      601 ctccattgtg ctggatggcg cgataataga agatgacgta atgattggcg cgggaagcct
      661 ggtgccgcag cacaaacggc tggaaagcgg ctatttatat cttggcagtc cggtaaaaca
      721 gatccgcccc ctgagcgatg ctgagagatc gggcctgcag tactccgcca ataactatgt
      781 aaaatggaaa gacgactatc tttctcagga taaccatatc caaccgtgat cgtcttcctg
      841 ctgggccagg attaatgctt cagcctcttc ttccaggtcc cagcgatact cacgaaaaat
      901 ggccagccat tgctccgctg tttctccacc aaagcgatac gccagtacat ctttttttat
      961 cgcacacgtg atttgcatcc cattgaccag ggcgggaaag atgatagcgc tggcggcagt
     1021 atcccattct tcgcggtcag ggaattgtat ggcctggttc acgctaataa ttcctgctgt
     1081 agcagcttaa tcactggctc gacctgcggt aatacaccgt gccaaagcaa aacggcatgt
     1141 gcagcctgcc ccaccagcat tcccagccca tctgcgtagc gtttcgcgcc ctgttgtaca
     1201 caccaggaga gaaatggcgt attccctttt tgatagaaca tgtcatagca acagagggaa
     1261 ggatgaataa gtgacgccgg aatcgccggg atttcgcccc gtatgccgct ggaggtcgca
     1321 ttaataatca ggtcaaactc acaaccatcc agcttgtcca tatccatagc atgaacgctg
     1381 ccggtatgag caaagatttt cgccaacgct tcggcacgtg aagctgtacg gttagtgata
     1441 gtgaccgcac aatccaaaga aagcaggggt aacagcacgc cccgggatgc gccgcccgcg
     1501 ccaatcagca aaatacgcaa tcctgggcgg ataaaattta aacgttcgag atcgcttaat
     1561 aaaccgatac cgtcagtatt gtcgccaagc aaacgaccat cttccagccg ttttaatgta
     1621 ttgacggctc ccgccagcga tgctcgttcc gttaactcat ccgaacgcgc aaacgcctcc
     1681 tctttaaaag gtactgtgat gtttgcgcct tttccccctg ccgcgaaaaa ggcatcaagc
     1741 gtattaatga aattattaat gggggccagc acgcgaccat aggggtgaac aatatctagc
     1801 tgctgagcaa attgctgatg aataaatggc gatttgctgt gcgcaatcgg atttccaaaa
     1861 acagcatagg cttccatcat attacccctg tcgaaatagt tcgcccgtca gagcatcgcg
     1921 gatttctgaa ggatttaaac gcccacccgt tgcgccttca accaccggaa aatcatcgcc
     1981 aaattgcgca cgcacctctt caacggtacg gcatggcggt aatccgctca gattggcgct
     2041 ggtggaaacc agcggtttgc catacgcatt gcatagcgcg accaccagcg ggtggttggt
     2101 aacacgaacg gccagggaat caaaacgtcc cgtgagccac cgcggcgttg tcgcgggcgc
     2161 aggaaaaaca aacgttaccg gcccgggcca gcaatcaaat accgctttac gctgtgcggc
     2221 ggtaagtatg ctgtcatcaa tataaggttt taactgctca aagctggcgg caatcaaaat
     2281 gagtccctta tcgacgggcc gttgttttaa cgccagcagg cgcgtaacgg ctgtttcact
     2341 atcgggatcg cagccgacgc cgaaaacggc ttctgttgga taagcgatga cattttcttt
     2401 attcaggaga tctaccaccg cggcgctaga tcctgttggc aggttattat tcacttgttt
     2461 attccaccgg aaccggcttt ccacattgtt tactggcgca aaagcgcttc acgccctgcg
     2521 cggttttctt ttcgatgagt agcgaataat ggcactcggg gcattccccc gcaaccggtg
     2581 tgaagttaat gacgaactga cattccgggt agcgatcgca ggaatgaaag attttaccgt
     2641 aacgagaacg gcgctggacc aaatgtcctt gctggcaggc tggacaggca atcgccgttt
     2701 catccggttt atcaataacc actgtatgtt cacattgcgg atactgactg catccgatga
     2761 acatgccaaa gcgcccctga cgcagcacca gtacggcgcc acactcagga cacagttgcc
     2821 cctccagaat tttaacgata tgtccgtccg cctgactttt cagcggacga acgtaatcgc
     2881 attccggata gcgagaacag ccgagaaacg gaccatgttt cccggaacga attaccagtt
     2941 cggccccgca ctgcgggcag ggctcatttt tacgcaccga aaacagtgct gatttagcca
     3001 tattcactca tgcagcatta acacctatca atgcagcata ccttcattta cctcaaagag
     3061 taattcttcc atttgctgat aggcgttttc acagcccgga atgttgaata acaccatcaa
     3121 aataacccat ttcaagtctt ccaggtcaaa ctctgcggta tccagcgcca gcacacgctc
     3181 aatcaccatt tctcgtgttt cgaggtttag cacctgaatc tgctcaagga ataacaggaa
     3241 cccccggcaa ctggcatcaa gcctttcaca ttcttcaacc gtataaatgc gcattgaaag
     3301 agggtcggaa gcaagttgca tgggttccgc gaggccatcc tgatagtcag cgagtttttc
     3361 cagccacagc agcgcattgt agatgtcttc gcgatcaaac ccagcgtcgg tgagatcacg
     3421 ctccagtctg tcctgatcca cgcgcagctc ggcttcgtta tggatgtatg tttcaaacaa
     3481 atacattagt acgtcgaaca tggcttgccc tccttaatcg gacatagccg ccgggtacag
     3541 ctgcgatcca tcctgctaac tccagttcga gtagctgagc cactaccgct ggcacaggtt
     3601 ggccggcacg ttcagcgacg acgtcaacag gtgttacctc atctcctacg ttagccagga
     3661 gctcaggaaa tggcaatgcc gcctcatcct gatttagtga ataaagtgaa ttttccgccg
     3721 tagttggcaa ccagtgtaag ccgtattgca aattttccag aatatcctcc ggcgtcgtca
     3781 caagcgtggc cccttgttta attaaccagt gcgtgccttc gcttcccgga ctaccgatag
     3841 ggcctggtaa tgcaaaaacg tcccgcccct gttcaagcgc gcagcgcgcc gtcaccaacg
     3901 aaccgctgcg caacgccgcc tcaatcacca gtacgccttt gctcagtccg ctgatgatac
     3961 ggtttctgcg aggaaaattt tgcgatagcg gaggcgttga aagcggaaat tctgagacca
     4021 ctgcgccgcc agtggcaatc aagttttcag ccagcatggc atgtcggcga ggataaatct
     4081 ttgccaagcc attccctaac accgctacac tttttccccc catactcatc gcggcgttgt
     4141 gtgctacgcc atcaattcct cgggcaaggc cgctggtgat cgtcaaaccg cttttcgcaa
     4201 ggctttcgca aagcagacgt ccccagcgtt ctccatacca ggagtggctc cggctcccga
     4261 cgacggcaag ttggcaggta tgcagacagg caggatcgcc gtcaataaaa atagcgccgg
     4321 gataatcgtc aatagcacgc agttgaggag gataaatctc actatccgca cacagaaaat
     4381 ggtgctgcgg tagttcaagc cagcgtaacg tctcatcaag cacacctgct ggaagctgta
     4441 aaaaacgttc agcttgccgc gcagtaagac cagcctcctg aaggtgcgtg cgatttatct
     4501 gaggctggcg aataagcgaa ttcgccatgt tcaacatcgc ctcgccataa aggtcgccga
     4561 cgtacattaa acgtaaccaa atttcggtac gggccatcct ttccctcccc tgccacaagc
     4621 agtctgaaca atctttgcga ttggtcactg atgctgtcaa tcaggtgggg atttgtctag
     4681 aatagaggta ataatctttt caactcctga acacaactct ggataattat gtcagttttg
     4741 caagtgttac atattccgga cgagcgcctt cgcaaagtcg caaagccggt tgaagaagtg
     4801 aatgcagaaa ttcagcgtat cgtcgatgat atgttcgaaa cgatgtacgc ggaagaaggt
     4861 atcggtctgg ccgcaacgca ggtcgatatc caccagcgga tcatcgtgat tgacgtttcg
     4921 gaaaaccgcg acgagcgcct ggtactcatt aacccggaat tgctggagaa aagtggcgaa
     4981 acgggtatag aagaaggctg tctgtcgatc ccggaacagc gcgctttagt gccgcgcgcc
     5041 gagaaagtga aaatccgcgc gctggatcgc aacggcaacc cgtttgagct tgaagcggat
     5101 ggtttgctgg caatctgcat tcagcatgag atggatcacc tggtcggtaa actgtttatc
     5161 gattatttgt cgccgctgaa gcaacaacgt attcgtcaga aagtagaaaa actcgaccgc
     5221 ctgaacgccc gggcttaaag gacaagaacc aacgtgtcag attcactacg tattattttt
     5281 gcgggtacac ctgactttgc agcgcgtcat ctcgacgcgc tgttaacttc tggacataac
     5341 attgtcggcg tatttaccca acccgatcgt ccagcaggtc gcggcaaaaa gttgatgccc
     5401 agcccggtaa aagtgctggc ggaagaaaaa ggcctgcccg ttttccagcc cgtgtcgctt
     5461 cgtcctcagg aaaaccagca tctggtggct gacttacatg ccgacgtcat ggttgtcgta
     5521 gcatatggtc tgattctccc aaaggcagtg ctggatatgc cccgtctcgg atgtatcaac
     5581 gttcacggtt cgctgcttcc acgctggcgc ggcgcggcgc ctattcagcg ctcactctgg
     5641 gcaggcgatg cggaaaccgg cgtcacaatt atgcagatgg atgtagggct ggataccggc
     5701 gacatgctgt ataaacttgc gtgcccgatt accgcagaag ataccagtgg ctcactgtat
     5761 aataagttgg ctgaacttgg cccacagggg ttaattacca cactaaaaca actggcggac
     5821 ggcacagcga cgcctgaagc gcagaatgaa gcgctggtca ctcatgcgga aaagctcagt
     5881 aaagaagaag cgcgtatcga ctggtctctc tccgcagcac agctggagcg ttgcattcgc
     5941 gcctttaatc cgtggccaat gagctggctg gaaatcgacg gccagccggt aaaagtctgg
     6001 caggcatccg tcattgagga cgccacgcag tcgctgccgg gaaccattct ggccgcgacg
     6061 aaacagggca ttcaggttgc aacaggcaag gggatattaa atttgctttc gcttcagcct
     6121 gccggcaaaa aagcgatgag cgcccaggat ctgttaaatt cacgccggga atggtttatc
     6181 cctggtaacc gccttgcctg acggtcacgt ctttatacgc ccggtgttac cgggcatttt
     6241 tattttatac atatgaaaaa acaaaacaat ttacgtagtc tggcagcaca ggccgttgaa
     6301 ctggtcgtcg aacagggaca atcattaagt aatgtgctcc cgccgctgca acaaaaagtc
     6361 gccgataaag acaaagcgct acttcaggag ctgtgctttg gcgtcctgcg caccctttca
     6421 cagctggaat ggctgatcaa taagctgatg tctcgtccaa tgaccggcaa gcagcgtaca
     6481 gtgcattact taattatggt cggcttttat cagttgctgt acacccgcgt ccctccccat
     6541 gcggcgctgg ctgaaaccgt tgaaggcgcg gtctccatca aacgtccgca gttgaaaggg
     6601 ttaattaacg gcgtcctgcg ccagttccag cgccagcagg aaacgttgct taatgagttt
     6661 gcgaccagcg atgcgcgctt tttacatccc ggttggctgg taaagcgttt gcaaaatgct
     6721 taccccacac agtggcaacg cattattgaa gcgaataacc agcgtccacc tatgtggcta
     6781 cgtgtaaatc gtacacacca cacccgcgac ggttggcttg gcttacttga agacgcaggc
     6841 atgaagggat atccccatcc cgattatccc gacgctgtgc gtctggaaac gccagctccg
     6901 gtacatgctt tacccggttt tgctgagggt tgggtaactg tccaggatgc ctctgcgcag
     6961 ggatgtgcgg tttttctcgc tcctcagaac ggtgagcaca ttttagactt gtgcgccgcg
     7021 cccggcggta aaaccacgca tattctcgaa gtggcccccg aagcagacgt gttggcggtt
     7081 gatattgatg aacaacggct ctcccgcgtt tacgacaacc taaagcgcct tgggatgaaa
     7141 gcgacagtta aacaagggga tggacgttat cccgcccaat ggtgcggcga gcagcagttt
     7201 gaccgtattc tgctggatgc gccctgctcc gcaaccggcg tcattcgccg tcatccagat
     7261 atcaaatggc tgcgtcgcga tcgcgatatc gcggaactgg cgcaattaca ggcggaaatt
     7321 cttgatgccg tctggccgcg cctgaagccc ggcgggacgc tggtttatgc cacctgttcc
     7381 gtactgccgg aagaaaaccg cgatcagatc aaagcctttt tgcaacgcac tcccgatgcc
     7441 gcgctcagcg aaacgggaac acctgatcag ccaggacagc aaaatctgcc gggcggcgaa
     7501 gaaggtgatg ggttctttta cgctaagcta atcaagaagt gatgagataa cgggccacga
     7561 ctgatgaaaa ttatcatact gggcgcaggg caagttggtg gaacactggc ggaaaacctg
     7621 gtcggcgaaa acaacgacat cacggtggtt gataccaacg gcgaacgatt acgcagtttg
     7681 caagataagt tcgatctacg cgtagttcag gggcatggtt cgcatccccg cgtgttgcgc
     7741 gaagcgggcg ctgacgatgc ggatatgctg gtcgctgtca ccagttcaga tgaaactaat
     7801 atggttgcct gtcaggtagc ctattcactc ttcaacaccc caaaccgtat cgcccgcatt
     7861 cgctccccgg actatgttcg cgatgcggat aaactctttc attctgaagc ggttccgatt
     7921 gatcatctga tcgcgccgga gcagttggtt atcgataata tttatcgtct gatcgagtat
     7981 ccgggagcat tacaggttgt aaactttgcc gaagggaaag tcagtctggc agtagtaaaa
     8041 gcctactatg gcggtccact aataggtaac gcgctctcga caatgcgaga gcatatgccg
     8101 catatcgata cccgcgttgc cgcaattttc cgtcatgaca gaccaatccg tcctcagggc
     8161 tcgactatcg tggaagcagg ggatgaagtc ttctttattg cggcttcaca gcatatccgt
     8221 gcagtaatga gcgaattaca gcgtctggaa aaaccctaca agcgcatcat gctggtgggc
     8281 ggcggcaata tcggcgccgg gctggcaagg cgtctggaaa aagactatag cgttaaattg
     8341 atcgaacgcg atcaacaacg cgccgcagaa ctggctgaga agctgcaaaa cacgatcgtc
     8401 ttttttggcg acgcttccga tcaggaattg ctggcggagg agcatattga tcaggtcgat
     8461 ctctttatcg cagtcactaa cgatgacgaa gccaatatca tgtccgcgat gttggctaag
     8521 cggatgggcg ccaaaaaagt gatggtgctg attcagcgtc gagcttatgt cgatcttgtg
     8581 cagggtagcg ttatagatat tgcgatttct ccgcagcagg ccaccatctc tgcattactg
     8641 agccatgtgc gtaaagcaga tatcgtcggc gtttcctcac tacgtcgcgg ggttgccgaa
     8701 gccatcgaag ccgtcgcgca cggcgatgaa agcacttccc gcgtggttgg ccgcgtcatt
     8761 gacgaaataa aactgccgcc aggcaccatt attggcgcgg tcgttcgcgg taatgatgtc
     8821 atgattgcta atgacaattt gcgcattgaa caaggcgatc acgtcattat gtttttgacc
     8881 gataaaaagt ttattaccga cgtcgaacgt ctgttccagc caagtccttt cttcctctaa
     8941 tttaaggggc gctcattcag cgcccttttt aattcccttt atttatcaag gtttaattta
     9001 tttcgctaaa cagaagccgt aaatggaaaa tgccttagca tttgttaaac ttataacgtc
     9061 agctgcatag ggagaataaa aatgagtttt attaaagaat tccgcgaatt cgcgatgcgc
     9121 gggaatgttg tggatttggc agtgggtgtc attattggcg cggcattcgg taagattgtt
     9181 tcttcactgg ttgccgatat cattatgccg ccgttgggat tgttaatcgg cgggatcgac
     9241 tttaaacaat ttgcttttac gttacgcgaa gcgcagggag atattccggc ggtcgtcatg
     9301 cattacggcg tgtttatcca gaacgtattt gattttgtga ttgtggcgtt tgctatcttt
     9361 gttgccatta agcttatcaa cagactcaac cgtaaaaaag cagaagagcc ggcagctccg
     9421 cccgcgcctt ctaaagagga agtgttattg ggcgaaatcc gcgatctgct gaaagaacaa
     9481 aataaccgtt cttaataagc agaaggccag tggtaaaaaa gtcacttact ttcttgccac
     9541 tggcctccca gttcccccgg ttaccgtgtt tacctttacg cagataactt cctttgcctt
     9601 tcttattttt ttcaacgcgt tgcctgaaaa ggggatcgtg taacaatgcc tcgatggcat
     9661 tgtcctttat ctgccctttc ttatgttgat aacgactcat aatatctccc gtttgtataa
     9721 attatacggc gcgagtgtag tcccgccggt tcaataaatc aacatactga tttcgcccca
     9781 ctggccccct gttccagggc ttccagaatg gaacaataga cgctactgtg ggccgttccg
     9841 caacaagcat cattaagcct ttgtaacgaa cgctgcatcg tttgcagttc cgcaatcctg
     9901 gcttcaacct cctgcaatcg ttcttgcaca atactttttg actcctgaca ggtatggtgc
     9961 tcaggatcaa ttctgatcga taaaagttcg cggatcgact caagcgtgaa acccaactgc
    10021 cgcgcataac gaataaactt gagacgctgc agatcgtttt cggtatacag acgaaacccg
    10081 ccttcagtac gtacctcatg atccatcatc tgctgttttt catagtagcg aatggtatca
    10141 ggcgttacgt ctgccagctt tgccagctca ccaatgcgat acatacaagc tccgttaatt
    10201 atcgttgatt ttatgcagca gtttttctgc atactcaccg tgtaaaaaat cggtactcaa
    10261 cccagcctgc cgaagtttta gttcaagcag cgagagctgg cgactaacct gatggtattg
    10321 agggtcatct tcccggatac tgttgaggat atcaagtaac tgaatagcgt ctctgcgctg
    10381 ctccagttca gggggaagac agcccgcatt cttcagtaag cgataacccg cacgaagttc
    10441 cgctggcaca tgagaatcat catccagaat aagcggttcg ccgcggccag gcagattatc
    10501 aaactcgcct ttacgctgtg cctcgataat atgacgctct gcccactggt caagtaacca
    10561 catacgtcgc tccagggatt gaacgaaaag aatacaatta ttgtagatat gtggggttca
    10621 ggaggatata aaaaaacccg ccgaagcggg ttttttacgt tactacagat tactctgcag
    10681 cagcttctgt tttctctgaa cgatcaacca gctcgatgta tgccatcggc gcgttgtcgc
    10741 ctgcacggaa gccacacttc agaatgcgag tgtaaccacc ggcgcggctc gcgaaacgcg
    10801 ggcccagctc gttaaacagt tttgccacga tctcgttatc acgagtacgg gcgaatgcca
    10861 gacgacgatt agcaacgcta tcagtcttgg caagagtaat cagcggctca actacgcgac
    10921 gcagctcttt cgctttaggc agggtcgtct tgatgatttc atgacgaacc agtgaacctg
    10981 ccatgttgcg gaacatagcc tggcgatggc tgctgttgcg gttcagttga cgaccactct
    11041 tacgatggcg catgacctta tccttctcag taaaacctta acctgtgatc cggttactcg
    11101 tcagcgatgc ttgccggtgg ccagttttcc aggcgcatac ccagagacag tccacgggaa
    11161 gccagcacgt ctttaatctc ggtaagagat tttttaccca ggttaggcgt cttaagaagc
    11221 tcaacctcgg tacgctgtac cagatcaccg atatagtgga tagcttctgc cttgaggcag
    11281 ttagcagagc ggacagtcaa ttccagatcg tcaacagggc gcagcaggat cggatcgaat
    11341 tctggtttct cttctttcac ttccggttga cgtacatcac gtaaatcaac gaaagcttcc
    11401 agttgttcag ccaggatggt tgccgcacga cgaatcgcct cttcaggatc gattgtgccg
    11461 ttggtttcca tttcgatgac cagcttgtcc aggtcggtac gctgttctac acgcgctgct
    11521 tcaacattgt aggcaatacg ctctacaggg ctgtagcagg cgtcgaccag cagacggccg
    11581 attgggcgct catcttcttc cgaatgaatt cgggtagaag ccggcacata accacgaccg
    11641 cgctgaactt tgatacgcat actaatagac gcgttttcat cggtcaggtg gcagatcacg
    11701 tgctgcggct tgacgatttc gacatcccca tcatgggtga tatcggctgc agtcacaggg
    11761 ccaatgccag atttattcaa ggtaagaata acttcatctt taccctgaac tctcaccgcc
    11821 agccctttca ggttgagcag gatttccagg atgtcttcct gaacgccttc tttggtgctg
    11881 tactcatgta gtacaccatc aatctcaacc tcggtcaccg cgcaacccgg catcgatgag
    11941 agcagaatac ggcgcagtgc gttacccaga gtatggccga agccacgctc taaaggctca
    12001 agggtcacct tggcgtgcgt cgaactcact tgctcgatat ctaccaggcg cggttttaga
    12061 aactctgtca cagaaccctg cattgtgtcc tctctttggt actaagcttt acttggagta
    12121 aagctcgacg atcaggtgtt cgttaatgtc cgcagacaga tcagaacgct caggcttacg
    12181 cttgtacgta ccttccatct tgccagcatc aacttccagc caggttggct tttcacgctg
    12241 ctcagccagc tccagagcgg ctttcacgcg agactgcttc ttcgctttct cacgaatgct
    12301 aacaacgtca ttcggactaa cctgataaga agcgatgtta acaacacgac cgtttaccat
    12361 aattgcttta tggctaacca gctgacgtgc ttctgcacga gtggcgccga agcccatacg
    12421 gtatacaacg ttgtccagac gaccttccag cagagccaac aggttttcac cggtgttgcc
    12481 tttcagacgt gctgcttctt tgtagtagtt acggaactga cgctccagca caccgtaaat
    12541 gcggcgaact ttttgctttt cacgcaactg cacaccatag tcagacagac gcggcttacg
    12601 cgcaccgtgc tggccaggag cttgtccaat tttacacttg gtatcgatcg cgcgaacgcc
    12661 agacttaagg aataagtcgg tgccctcacg acggctcagc ttgagcttag gacccaaata
    12721 tcttgccatt ttctttctcc aactaacctg gaaaacgaag cgttatacgc gacgtttttt
    12781 cggcggacga caaccgttat gagggatcgg agtcacatca gtaatattag tgatgcggaa
    12841 accagcggcg ttcagagcac gaatagtaga ttcgcggcct ggacccggac ctttaaccat
    12901 aacttccaga ttcttgatac cgtattcttt cacggcgtca gcgcaacgct ctgctgcaac
    12961 ctgagctgca aacggagtgg atttgcgaga accacggaaa ccggaaccac cggctgttgc
    13021 ccaacccagc gcattaccct gacgatcggt aatagtcacg atggtgttgt tgaaagaagc
    13081 atggatatga gccacgccgt cagagacttg ttttcttaca cgtttacgtg cgcaaactgg
    13141 tgcctttgcc attattcaat caccccgatt atttcttgat cggtttgcac ggacccttac
    13201 gggtacgagc gttggtcttg gtacgctgac cgcgaaccgg gagaccacga cgatgacgca
    13261 aaccgcgata gcaaccaaga tccatcaggc gcttgatgct catgctgatt tcacggcgca
    13321 gatcaccttc aacgacaaat ttggcaactt cgtcacgcag cgtgtcgatt tgttcttcag
    13381 acagctcact gatcttaaca ttttcagcga tacccgctgc agccaggatg gctttagaac
    13441 gggtcttgcc gacaccgtag atcgaagtta acgcgatcac ggcgtgtttc tgatcaggaa
    13501 tgttaatgcc tgctatacgg gccactatgc actcctacta tttaatatgt acgtaccatg
    13561 ctgaaaagcc cgttttcagg atactcaaat ggaaacgtac agacatacaa aagattggct
    13621 ggctaatcta gccagctcaa cccaactttg caagaaaaat atgcgaaaaa atcagccttg
    13681 gcgctgttta tgcttcggct cggcactgca aatcacacgg atgacaccat cacgcttaac
    13741 gattttgcag ttacggcata atttcttgac ggaagcacga actttcattt ttactctccg
    13801 taacttctca ggcgaccaat taacggccgt agcctttcag gttcgccttc ttcaatgcag
    13861 actcatactg actggacatc atcagagttt gcacttgagc cataaagtcc ataatcacga
    13921 caacaacgat aagcagtgag gtcccaccga agtagaacgg cactttcatt gcatcacgca
    13981 tgaactccgg gatcaggcag ataaaggtaa tatacagcgc accaaccagg gtcaggtggg
    14041 tcattacttt atcgatatac ttcgccgttt gctctcccgg acgaattcct ggtacaaatg
    14101 caccggactt cttcaggtta tctgctgttt cacgcgggtt gaaaaccaac gccgtgtaga
    14161 agaaacagaa gaagatgatt gcagacgcat agagtaacac ataaagcggt tgcccaggct
    14221 gcaaatacag cgaaattgtt gtcagccagt tccaaccagt accgcccccg aaccatgacg
    14281 ctatggtcgc cgggaacaga ataatactgg aagcgaagat tgccgggatt acccccgcca
    14341 tattcacttt cagcggtaaa tgtgtgctct gtgcagcata gacacgacga ccttgctgac
    14401 gtttggcgta gtttaccaca atacggcgtt gaccacgttc aacgaatact acaaagaacg
    14461 tcactgcaaa tactaatact gcaaccaaca gcaacacgag gaagtgcagg tcgccttgac
    14521 gcgcttgctc gatagtatgg gcaatggctg gcgggagtcc cgcaacgata ccagcgaaga
    14581 tgatgattga gataccgtta ccgataccgc gctcagtaat ctgttcgccg agccacatca
    14641 ggaacatggt ccctgtaacc agacttacaa cagcggtgaa atagaatgca aagcctggat
    14701 tcatcaccag gccctgcata ccaggcatat tcggcaaacc ggtagcaata ccgatcgact
    14761 ggaatatcgc cagcaccaga gtaccgtaac gggtgtactg gctgatctta cgacgaccag
    14821 actccccttc tttcttaatt tctgcgagcg ttggatgaac caccgtcaac agctggataa
    14881 tgatcgacgc cgaaatatac ggcatgatcc ccagggcaaa gatagaagca cggctgagag
    14941 caccaccaga gaacatgtta aacatttcaa tgatggtgcc tcgctgttgc tcaagcagtt
    15001 tggcaagtac agcggcatca ataccaggga tcggaataaa agagccaata cggaacacaa
    15061 tcagcgcgcc gataacaaac agcagtctgc gtttcagctc acctaagcca cctttggcac
    15121 tttgaaaatc taatcccggt tgtttagcca tctgctactt attcctcgat tttaccgcca
    15181 gcagcttcga tagcagcacg agcgccttta gtaacacgca ggccacgaac agttaccgga
    15241 gtagtgactt cgccagccag gatcactttc gcgaactcga tctggatacc gataatgttt
    15301 gccgctttca gcgtgttcag gtctacaacg ccgccttcta ctttcgccag gtcagacaga
    15361 cgaacttcgg ctgtaatcgc tgctttgcga gaagtgaagc cgaatttcgg cagacgacgg
    15421 tacagaggca tctgaccacc ctcgaaaccg cgacgtacgc caccgccaga acgagacttc
    15481 tgacctttgt gaccacgacc accggtttta ccgaggccag aaccgatacc acgacccagg
    15541 cgtttacccg cctttttgga gccttcggcc ggagacagag tatttaaacg catctcttac
    15601 tcctcaactt taaccatgaa ggaaaccgcg ttgaccatac cacgaacagc aggagtatcc
    15661 tcgcgctcta cggtgtggcc aatacgacgc agacccaggc caagcagcgt tgccttgtgt
    15721 ttcggcagac gaccgattgc actgcgggtt tgagtaattt taatagtctt tgccatggtt
    15781 tatttcccca gaatttcttc aacggattta ccacgcttgg cagcgaccat ttctggagaa
    15841 ttcatatttt ccaggccatc aatagttgca cgaaccacgt tgatcgggtt ggtggaaccg
    15901 tatgctttag ccagaacgtt atgaacccca gcaacttcca gaacggcgcg cattgcacca
    15961 ccggcgatga taccggtacc ttcggaagct ggctgcatga atacacgaga ccccgtgtga
    16021 acacctttaa ccgggtgctg cagggtgccg ttgttcagcg cgacgttaat catattgcga
    16081 cgggcttttt ccatcgcttt ctggatcgct gctggaactt cacgcgcttt accgtaacca
    16141 aaacctacgc gaccgttacc atcgcctact acagtcagag ctgtgaagga gaaaatacga
    16201 ccacctttaa cggttttaga tacgcggttt accgcgatca gcttttcctg cagttcgcca
    16261 gcttgttttt cgatgtgagc catcttacac ctctacctta gaactgaagg ccagcttcac
    16321 gggcagcatc tgccagtgcc tggacacgac catgatattg gaacccggaa cggtcaaagg
    16381 acacatcttt gatgcctttt tccagagcgc gttcagcgac agctttaccc acagctgcag
    16441 ccgcatcttt gttaccggtg tacttcagtt gttcagcgat agctttttct acagtagaag
    16501 cagctaccag aacttcagaa ccgttcggtg caattacctg tgcgtaaata tgacgcgggg
    16561 tacgatgtac caccaggcga gttgcgccca gctctttgag cttgcggcgt gcgcgggtcg
    16621 cacgacggat acgagcagat ttcttatcca tagtgttacc ttacttcttc ttagcctctt
    16681 tggtacgcac gacttcgtcg gcgtaacgaa cacccttgcc tttgtaaggc tcaggacgac
    16741 ggtaggcgcg cagatctgct gcaacctggc cgatcacctg cttatcagcg cctttcagca
    16801 cgatttcagt ttgagtcgga cattcagcag tgatacctgc cggcagctga tggtcaaccg
    16861 ggtgagagaa acctaaagac aggtttacta cattcccttt aaccgctgca cgataaccta
    16921 caccaaccag ctgcagcttc ttagtgaagc cttcggtaac accgataacc attgagttca
    16981 gcagggcacg cgcggtacca gcctgtgccc aaccgtctgc gtaaccatca cgcggaccga
    17041 aggtcagtgc attatctgca tgtttaactt caacagcatc gttgagagta cgagtcagct
    17101 cgccgttttt acctttgatc gtaataacct gaccgttgat tttgacatca acgccggcag
    17161 gaacaacgac cggtgcttta gcaacacgag acattttttc ctccgattag gctacgtagc
    17221 agataatttc gccaccaaga ccagcctggc gcgctgcacg atctgtcata acacctttag
    17281 aggtagaaac aactgcgata cccagaccgg ccataacttt cggcagctca tctttacgtt
    17341 tgtagatgcg caggcctggg cggctgacac gctgaatgct ttctacaaca gctttaccct
    17401 ggaaatactt aagagtcagt tccagttccg gcttggtgtc gccttcaact ttaaaatctt
    17461 caataaaacc ttcttccttc agcacgttgg caattgccac tttcagctta gaggaaggca
    17521 tggtgaccgc agctttgttc gcggcctgac cgttacggat acgggtcagc atatccgcga
    17581 tcggatcttg catgctcatc tgtctttact cccgtgattc aattggtgac aattaccagc
    17641 tagccttttt cagacccgga atttcaccgc gcatagcggc ttcacggacc ttaatacggc
    17701 tcaacccgaa cttccgcagg aaagcgtgcg gacgaccagt ttgacggcag cggttacgct
    17761 gacgtgacgg gctggaatca cgcggcagag tctgcagctt aagaaccgca ttccaacgat
    17821 cttcgtcggt tgcgttcaca tcagagatga tcgctttcag ttcagcgcgt ttcgcgaagt
    17881 atttatcagc taaagctacg cgttttactt cgcgtgcttt cattgattgc ttagccattt
    17941 agtaacccta ccttacttgc ggaacgggaa gtcaaaggca gccagcagag cacggccttc
    18001 ttcgtcagat ttcgcagtag tggtaatggt aatatccaaa ccacgaacgc ggtcgacttt
    18061 atcgtagtcg atttctggga agatgatctg ctcacggaca cccatgctgt agttaccacg
    18121 accgtcgaat gacttagcgg acaagccacg gaagtcacgg atacgaggaa cagcaatagt
    18181 gatcaggcgc tcaaagaact cccacatgcg ttcgccacgc agagttactt tacagccgat
    18241 cggatagccc tgacggattt tgaagcctgc aacagatttg cgtgctttgg tgatcaacgg
    18301 tttttgaccg gagattgctg tcaggtctgc tgctgcgtta tccagcagtt tcttgtcagc
    18361 gatcgcttca ccaacaccca tgttcagggt gatcttctcg acccgaggga cttgcatgac
    18421 agaattgtag ttaaactcag tcatgagttt gttaactact tcgtctttgt agtaatcatg
    18481 cagtttcgcc atcgtactac tccaaattac ttgatagttt cgctgttaga cttgaagaaa
    18541 cggacttttt tgccgtcttc gaatctaaag cctacacggt cagccttgcc ggttgccgta
    18601 ttgaagattg caacgttaga aacctgaatt gcagcttctt tttcaacgat gccgcccggt
    18661 tggttcagag ccggaaccgg cttctggtgt ttcttaacca ggttgatacc ttcaacaatg
    18721 accttgccgg aagacaggac attcttaact ttaccgcgtt tacctttatc tttaccggtt
    18781 aacacgataa cttcgtcatc acgacggatt ttcgctgcca tgattcgctc cttagagtac
    18841 ttctggtgcc agagagataa ttttcatgaa cttctcgtta cgaagttcac gagttaccgg
    18901 cccaaaaata cgcgtaccga taggctgctc gctgttattg tttaaaataa cgcatgcatt
    18961 accatcgaag cgaatgacag aaccgtccgg gcgacgaaca cccttcttgg tgcgcaccac
    19021 taccgccttc agcacatcac cttttttgac cttaccacgc ggaatcgctt ctttgatggt
    19081 gatcttaatg atgtcgccta cgcctgcgta gcgacggtgc gagccaccca gaaccttgat
    19141 acacattacg cgacgtgcac cggagttgtc ggcgacgttc agcatagtct gttcttggat
    19201 cattttagtg ctccgctaat gtcaactact actgagaccc gaaaatcagg tcgttaaaaa
    19261 aaccccatat cgagggcgcg gcattataac accgcaaatc agatatgggt agaaaaaata
    19321 aacggcccat cgctgagccg tttattcgtt gagaatgcgt actgtattac agaaccgctt
    19381 tctctacaac gcgaaccaga gtccaggatt tggtcttgga cagcggacgg cattcgcgga
    19441 tttcaaccac gtcgccgata ccgcattcgt tgttctcgtc atgtacgtgc attttggtcg
    19501 tacgcttgat gaatttaccg tagatcgggt gtttcacaaa acgttcgata gcaacaacaa
    19561 tggatttctc cattttgtcg ctaaccacgc gaccttgcag agtacggatt ttatcggtca
    19621 ttacgcaccc gccttctcag tcagtaaagt cttaacgcgt gcgacatcac gacgcacttg
    19681 cttcaacagg tgagactgtt gcagctggcc acttgcagcc tgcatacgca ggttgaactg
    19741 ctcacgcagc aggttcagta gctcggtgtt cagctcttca acgctcttct cacgcagctc
    19801 ttttgctttc attacatcac cgtcttagtt acaaaggtgg ttttaatcgg cagtttcgct
    19861 gctgccagct tgaatgcttc acgggccagc tcttccggta cgccgtccat ttcatacagg
    19921 actttacccg gctgaatcaa ggcaacccaa tactccacgt tacctttacc tttacccata
    19981 cgcactgcca gcggcttttc agtgatcggt ttgtccggga atacacggat ccagatctta
    20041 ccttgacgct taactgcacg ggtcatagca cgacgtgctg cttcgatctg acgggcagtc
    20101 agacgaccac ggccaacagc tttcaggccg aagctgccga agctaacatc cgcgcctgca
    20161 gccagaccac ggttgcggcc tttgtgcatt ttacggaatt ttgtacgctt tggttgtaac
    20221 atcagcgacg ctccttattt acggccttta cgctgctgct ttttcggttg agcagccggt
    20281 ttttccggtt gttcaacagc agccatacca cccaggatct cgcctttgaa gatccacact
    20341 ttaacgccga ttacaccata agtggtgtgc gcttcagagg tgttgtagtc gatgtcagca
    20401 cgcagagtgt gcagcggtac gcgaccttcg cggtaccatt cggtacgtgc gatttccgcg
    20461 ccgcccagac ggccgctaac ttcaactttg atacctttag cgcccagacg catggcgttc
    20521 tgtacagcac gcttcatcgc acgacggaac ataacgcgac gttccagctg agaagtgatg
    20581 ctgtcagcaa ccagtttagc gtccagttca ggtttacgaa cttcggcgat gttgatctgt
    20641 gcaggaacgc cagcgatatc cgctacgacc ttacgcagtt tttctacgtc ttcacctttt
    20701 ttaccgataa cgatacccgg gcgagcggtg tgaatagtca cacggatgct cttagccgga
    20761 cgctcgataa cgatacgaga tacagacgct ttagccagtt ccttcgtcag gtactgacgt
    20821 actttaaaat cgctgtccag gttgtcagcg aattctttgg tgttcgcaaa ccaggtagag
    20881 ttccatggtt ttacaatacc caggcgaata ccattaggat gtactttctg acccattgct
    20941 agtctccaga gtctcagcga tcggacacaa ccacagtgat gtggctggtg cgcttcagga
    21001 tgcgatctgc acgacctttt gcacgcggca taatgcgctt catgctcggg ccttcgtcta
    21061 cgaaaatttt cgtaactttc agatcgtcaa tgtcagcgcc atcgttgtgt tcagcgttag
    21121 caatggcaga ttccagaact ttcttgacca gtacagccgc tttcttgttg gtgtaggtca
    21181 gaatatccag agcctgcgac actttcttac cgcgaatcag gtcagcaaca aggcgaacct
    21241 tctgagcaga agaacgagca tggcgatgtt tagcgatagt ttccatctct tcctcctacc
    21301 ttatttcttc ttcgcttttt tatcagcagc gtggccgcga taagtacgag tcggtgcgaa
    21361 ttcacccagt ttgtgaccga ccatttcgtc ggaaacaaat accggaacgt gctgacgacc
    21421 attatggaca gcgatggtca aaccgatcat gttaggaaag atcgttgaac gacgggacca
    21481 agtgcgcagg ggcttcttgt ctccgctttc caccgctttc tctaccttct tcagcaagtg
    21541 caggtcaata aaaggacctt tcttgagaga acgtggcatg gcttatcctc taaaattatt
    21601 tgctacggcg acgtacgatg aatttatcag tacgcttgtt gctgcgggtc ttcttacctt
    21661 tggtctgaac gccccacgga gttaccgggt gcttaccaaa gttacgacct tcaccaccac
    21721 catgtgggtg gtctactggg ttcatcgcag taccgcgaac ggtaggacga acgccacgcc
    21781 agcgtgcagc acctgcttta cccagaacgc gcagcatatg ctcagcattg ccaacttcgc
    21841 ccagggttgc acggcagtct gcttcgactt tacgcatttc accagaacgc agacgcaggg
    21901 tgacataagc gccatcgcga gcaacgatct gaacgtaagt accagcggaa cgcgccagct
    21961 gaccgccttt acctggtttc atttctacgt tatgaacggt agaaccaacc gggatattgc
    22021 gcatcggcag ggtgttgcct gctttgattg cagcatcaac gccagactga atctggtcgc
    22081 cagctttcag gcctttcggg gccaggatgt aacggcgttc gccgtctttg tacagaacca
    22141 gcgcgatgtt cgcggaacgg ttcggatcgt actcaagacg ttcaacaact gccgggatac
    22201 cgtctttgtt gcgtttgaag tcaacaatac gataagcctg tttgtgacca ccaccgatat
    22261 gacgagtggt gatacggcca ttgttgttac gaccaccgga tttgctgttt ttttcaacca
    22321 gcggagcaaa aggtttgccc ttgtgcagct ctgggttgac cactttaacg acgtggcgac
    22381 gacccggaga tgtcggttta catttaacaa ctgccattgt attactcctc cgacttactc
    22441 agcgccgccg acgaagtcca gattctggcc ttctttcagg gtgacgtaag cttttttcca
    22501 gtcgctacga cgaccgatac gctgtccgtg acgtttaact ttccctttaa cgaccagggt
    22561 gttaacgact tcgacttcga cttcaaacag tttctgcaca gcagctttga tttctgcttt
    22621 ggtcgcgtct ttagcaactt tgagaacgat ggtgttggtt ttttccatcg cagtagacgc
    22681 tttttcagaa acgtgcggtg cgcgcagcac cttcagcaga cgttcttcac gaatcatgcc
    22741 agcatctcct caacttgctt aacagcatca gcagtcatta cgactttgtc gaaggcgatc
    22801 aggctaaccg ggtcgatacc agtcgcatcg cgtacgtcaa ccttgtgcag gttacgtgcg
    22861 gccaggaaca ggttctcgtc cagctcaccg gtgatgatca gcacatcttc cagagccatg
    22921 tctttcagtt tctgtgccag cagcttagtt ttcggcgctt ctacagagaa cttctcgaca
    22981 acgatcagac gatcctgacg taccagttcg gacaggatgc ttttcagcgc gccgcggtac
    23041 atcttcttgt taactttttg actgtggtcc tgcggacgag cagcgaaggt cacgccaccg
    23101 gaacgccaga tcgggctctt gatagaacct gaacgcgcac ggccagtgcc tttctggcgc
    23161 cacggttttt taccggaacc agttacttca gcacgagtct tctgagcacg agtaccctga
    23221 cgagcaccag ctgcataagc aacaacaacc tggtgaacca gcgcttcgtt gaaatcacga
    23281 ccgaaggtag tttcggaaac agtcagcgcg ctctgcgcgt ctttcaatac taattccatt
    23341 gctatcccct tacgccttca cagctggttt aacgatcagg tcgcaaccgg ttgcacccgg
    23401 aacaccaccc ttaaccagca gcaggttgcg ctcagcgtca acgcgtacta cgtcaaggct
    23461 ctgaacggtt acgcgctcat tacccatctg acctgccatt ttcttgcctt tgaacacttt
    23521 gcccggagtc tggttctgac cgatagaacc cggaacgcgg tgagacaagg agttaccgtg
    23581 agtagcgtcc tgggtacgga agttccagcg cttaacggta ccagcgaaac ctttaccttt
    23641 agaggtaccg gttacgtcaa cttttttaac gtcagcaaac agttcaacgc tgatgctctg
    23701 acctacggtg tattcttcgc cttcagccag acggaattcc cacagaccac ggccagcttc
    23761 tacgccagct ttagcaaagt gacccgcttc cggcttggtg acacggttag cttttttagc
    23821 acccgtagta acctgaacag cgcggtagcc atcgttagcc aggtctttaa cctgagtaac
    23881 acggtttgct tcaacttcga ttacggttac tgggatagag acgccatctt cagtgaagat
    23941 gcgggtcata cccacttttt taccgactaa accaatcatt gtatcaacct ctcaatcgct
    24001 cgatgacctg attaacccag gctgatctgc acgtctacac cggcagctag gtccagacgc
    24061 atcagagcat caacggtttt ctcggttggc tcaacgatgt caaccagacg cttgtgagtg
    24121 cgaatttcgt actgatcgcg cgcatctttg ttaacgtgcg gagagatcag aacggtaaag
    24181 cgctctttgc gggtcggcag cgggatcgga ccgcgaacct gcgcaccagt gcgcttggca
    24241 gtctcgacga tttccgcggt tgattgatcg atcagacgat gatcaaacgc tttcaggcgg
    24301 atacggattc tttggttctg catgagacca gagctccaat tattttataa acgaaaatga
    24361 ttactcctca cacccattac gattgatggg agagtgtaac cgttcttacg tagctccccg
    24421 attgggagca ttgttaaata gccaaatcgg ctattcgagg ttcaaatcga acctgccgtc
    24481 aattacgaca agcccgcgca ttatacgtaa atctcagcct gacgcaagtg tcggatagaa
    24541 attaagcgct ttattcttat gcgagcatga ttccagatgg tacgcatggg atggcgacgc
    24601 gcatcttttc tttggaaggc atcaggcaaa cctggcaata cgtcgttgtc gctgtcgcat
    24661 aaatctataa aggtgagcac aaaccttgac gaggatttgc ttatgtttgt tgccctcccc
    24721 tttctcattt tttatgcgtc gttctcttta ttacttggca tatacgacgc gcgtaccggt
    24781 ctgctacctg accggtttac ctgtccatta ctgtggggtg gtctgcttta tcaccagatt
    24841 tgcctgccgg agcgtttacc ggatgcgctt tggggcgcta tcgccggcta tggcggattc
    24901 gcgttaattt actggggcta tcgcctgcgt tatcagaaag aggggcttgg atatggcgac
    24961 gtcaagtacc ttgctgcctt aggggcgtgg cattgttggg aaacactgcc gttactggtt
    25021 ttccttgccg ctatgttggc ctgtggcagg tttggcgtcg cgctactggt gagaggtaaa
    25081 tcggcattaa taaacccgct accttttggg ccatggctgg cggtggcggg tttcataaca
    25141 ggttggaaag ttttctttcc agacggttaa tcggtaacct taatttgtga ttgcagataa
    25201 ttttgcatac caagtttggc aatcaaatcc agctcagttt ccagccagtc gatgtggcct
    25261 tcctcgtcgg caagaatttc aatcatcata tcccggctga cataatcatg aacgttatcg
    25321 gcataggcta ttgcctcacg tagatctttt gcgccttcca gttcgagccg gagatccgat
    25381 cgtagcatct cttcgacatc ttcaccgatg cccagcttgc ccagatcctg taggttcggt
    25441 atgccttcca gaaataaaat acgctcaata tacttatcgg cgtgtttcat ctcatcaatg
    25501 gattcatggt actcaacatc attaagccgg gtcagccccc agtttttgaa catacgggca
    25561 tgaagaaaat actgattaat tgcgacaagc tcatttccca atagtttatt gagataattt
    25621 atgattttaa catcaccttt cattttatag tccctccgct tccactctct agagcgtaga
    25681 tggggctaca gggatgtcaa aaaaaagagt gtgactcagg cgatctcttt aaattccggc
    25741 atttgcgtta actcatcctg catcacttct cgcgcggcgc gaatacactt accacattga
    25801 tttcccacag gaataaattt acgcaactgt tgaaatgact gtggatgaaa ttgtcgtaca
    25861 gcctggcgga tttttttatc gcttatacca ttacacaaac aaacgtacat gatcgctccc
    25921 gttcaatttc cgcacaaagt gtaaatgaga atggttatga ttacaatagc acaaagcgat
    25981 ttacgccacg ggagaagcgt taaaaaaggc aaataaatat aacagcggct aaatagcagg
    26041 caacaaaaag ggcgccgaag cgccctcttc aattcaaaac taattaacga gtaattagcc
    26101 cagaacttta gcaacaacgc ccgcgccaac ggtacggccg ccttcacgga ttgcgaaacg
    26161 cagaccgtcg tccattgcga tcgggtggat cagggtaaca accattttga tgttgtcgcc
    26221 cggcattacc atctctacgc cttccggcag ttcgatggtg ccagtcacgt cagtagtacg
    26281 gaagtagaac tgcggacggt agcctttgaa gaacggagta tgacggccgc cttcatcttt
    26341 ggacagaatg tacacttcag attcgaactt ggtgtgtggc ttgatggtgc ccggcttagc
    26401 cagtacctga ccacgttcga tttcttcacg tttgatacca cgcagcagaa cacctacgtt
    26461 ctcacc
//
LOCUS       DAJVKX010000054        26366 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000054 DAJVKX010000000
VERSION     DAJVKX010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26366
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.054"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            75..338
                     /gene="yhcN"
                     /locus_tag="OPY25_002352"
     CDS             75..338
                     /gene="yhcN"
                     /locus_tag="OPY25_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HCS0927954.1"
                     /translation="MKIKTTVATLSILSVLSFGAFAAEPISAEQAQNREAIGSVSVSA
                     IGSSPMDMNAMLSKKADEQGATAYHITEARSGSNWHATAELYK"
     gene            442..708
                     /gene="yhcN"
                     /locus_tag="OPY25_002353"
     CDS             442..708
                     /gene="yhcN"
                     /locus_tag="OPY25_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HCS0927955.1"
                     /translation="MKTKYIIASLGLATLLSFGANAAVHQVNAEQAQNLQPMGTISVS
                     QIGSTPMDMRQEIVAKAEKAGANSYRIIELKEGDNWHATAELYK"
     gene            complement(768..1040)
                     /locus_tag="OPY25_002354"
     CDS             complement(768..1040)
                     /locus_tag="OPY25_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0927956.1"
                     /translation="MNVYTFDFNDIKNQSDFYREFTQTFGLASEKVSDLDTLWDAVMS
                     DILPLPLEIEFVHLPDKLRRRYGALILLFDEAEEELEGRLRFNVRH"
     gene            complement(1212..3179)
                     /gene="aaeB"
                     /locus_tag="OPY25_002355"
     CDS             complement(1212..3179)
                     /gene="aaeB"
                     /locus_tag="OPY25_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HCS0927957.1"
                     /translation="MGIFSIANQHIRFAVKLACAIVLALFIGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGMLRIIGTFIGCIAALIIIISMIRAPLLMILVCCVW
                     AGFCTWISSLVRIENSYAWGLSGYTALIIVITIQTEPLLTPQFALERCSEIVIGIGCA
                     ILADLLFSPRSIKQEVDRELDCLLVAQYQLMQLCIKHGDSEEVDNAWGDLVRRTAALE
                     GMRSNLNMESSRWVRANRRLKALNTLSLTLITQSCETYLIQNTRPELITDTFRELFET
                     PVETVQDVHRQLKRMRRVIVWTGERETPVTLYSWVGAATRYLLLKRGVISNTKISATE
                     EEILQGEPVVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGNGAMVMIAVVTS
                     LAMRLPNPRMVCIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCLSLAVLGFFIGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFIQFLDSALGQIVGCMLAFIVILLVRDKSK
                     DRTGRVLLNQFVSAAVSAMTTNVVRRKENRLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSVFHRQLRRTADYVISAGSDDKRRRYFGQLLDELDIYQEK
                     LRIWEAPPQVTEPVKRLTGMLHKYQNALTDS"
     gene            complement(3185..4117)
                     /gene="aaeA"
                     /locus_tag="OPY25_002356"
     CDS             complement(3185..4117)
                     /gene="aaeA"
                     /locus_tag="OPY25_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HCS0927958.1"
                     /translation="MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFS
                     ADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGS
                     NRVLKGTVDSVAAGVTNASSTSDAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWP
                     AGTTATVVITGKQDRDASQDSFFRKLAHRLREFG"
     gene            complement(4125..4328)
                     /locus_tag="OPY25_002357"
     CDS             complement(4125..4328)
                     /locus_tag="OPY25_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HCS0927959.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRMLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            4510..5439
                     /gene="aaeR"
                     /locus_tag="OPY25_002358"
     CDS             4510..5439
                     /gene="aaeR"
                     /locus_tag="OPY25_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HCS0927960.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVAKLEDEL
                     QVKLLNRSTRSIGLTEAGKIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKLLKEYPGLAVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKPYLAQYGVPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGTGIAYVPLMWVIDEINRGDLEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINALTDYFVDVAHLFQGMHGRGKEK"
     gene            complement(5562..7007)
                     /gene="tldD"
                     /locus_tag="OPY25_002359"
     CDS             complement(5562..7007)
                     /gene="tldD"
                     /locus_tag="OPY25_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007888214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HCS0927961.1"
                     /translation="MSLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRE
                     NGEGKVKTLAAVAHQPLYTTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLT
                     GVYELILVAATDGTLAADVRPLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQIGEQVASALCTVVDDGTMMNRRGSVAIDDEGTPGQYNVLIENGVLKGYMQ
                     DKLNARLMGAAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTTPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(7152..10952)
                     /gene="yhdP"
                     /locus_tag="OPY25_002360"
     CDS             complement(7152..10952)
                     /gene="yhdP"
                     /locus_tag="OPY25_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HCS0927962.1"
                     /translation="MRRLPGILLLTGAALIVIAALLVSGLRLALPHLDAWRPAILNKI
                     ESVTGVPVAASQLSASWQNFGPTLEAHNIHAALKDGGELSIKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLNFRTNTPLQSSDGEGIETSRLSDLFLRQFDHFDLRDSQISFLTLSGQ
                     RAELAIPQLTWLNGKERHRAEGEVSLSSLTGQHGVMQVRMDLRDDDGLLNNGRVWLQA
                     DDIDVKPWLGKWMQDNVALQTARFSLEGWMTLSKGEIAGGDVWLKQGGASWLGDNTTH
                     TLSVDNLTAQISREQPGWQFYIPDTRITLDGKPWPSGALTVAWLPQQDVGGENHTRSD
                     ELRIRASNLELAGLEALRPLAAKLSPVLGEIWQATQPSGKIATLALDIPLQATEKTRF
                     QASWENLAWKQWKLLPGAEHFSGTLAGSVEDGQMKVAMQQAKMPYETVFRAPLEIENG
                     VATLSWLKNENGFQLDGRDIDVKAKAVHARGGFRYLQPTGDEPWLGILAGISTDDGSQ
                     AWRYFPENLMGKALVDYLSGAIQGGEADNATLVYGGNPHLFPYKHNEGQFEVLVPLRN
                     ATFAFQPDWPALKNLNIELDFLNDGLWMRSDSVDLGGVKASKLAAAIPDYSKEKLLID
                     ADINGPGKAVGPYFDETPLKDSLGSTLAELQLDGDVNARLHLDIPLDGEQVTAEGDVS
                     LRNNSLFIKPLNSTLKNLNGKFSFVNGALKSGPLTANWFNQPLNLDFSTTEGAKAYQV
                     AVNLNGNWQPTRMGVLPPQLNDALSGSVTWNGKVGIDLPYHADTTYHIELNGDLRNVS
                     SHLPSPLNKPAGEAIPVNIQADGNLKSFALTGSAGSKNHFNSRWLLNQKLTLDRAIWT
                     TDSRTIPPLPAQQGVELNLPALDGAQWLALFQKGAADNVSSSAEFPQRVTLRTPALSL
                     GGQQWNNLSVVSAPSLNGTKIEAQGREVNATLLMRNHAPWLANIKYLYYNPGVAKTHA
                     SSPTPTSPLASANTISFRGWPDLQLRCEECWLWGQKYGRIDGDFAIKGNTLTLANGLI
                     DTGFARLKANGEWVNAPGNERTSLKGSLHGSNLDTAAGFFGISTPIQNASFNVDYDLH
                     WRNPPWQPEEATLNGILRTRLGKGEFTDLSSGHAGQLLRLLSFDALLRKLRFDFRDTF
                     SEGFYFDSIHSTAWIKDGVLHTDDTLVDGLEADIAMKGSVDLVRRRLDMEAVVAAEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYRITGPVDAPQINEVLRQPRK
                     ESQQ"
     gene            complement(11063..12532)
                     /gene="rng"
                     /locus_tag="OPY25_002361"
     CDS             complement(11063..12532)
                     /gene="rng"
                     /locus_tag="OPY25_002361"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HCS0927963.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGDEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVCEEDLASDAAYLKRVWTKVMERKKRPQTRYQMYGELALAQR
                     VLRDFADAQLDRIRVDSRLTYESLLEFTAEYIPEMTSKLEHYSGHQPIFDLYDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSINGFSPLGLVEMTRKR
                     TRESVEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHALAEVEIFVGKQVKVQVEPLYNQEQFDVVMM"
     gene            complement(12522..13115)
                     /gene="maf"
                     /locus_tag="OPY25_002362"
     CDS             complement(12522..13115)
                     /gene="maf"
                     /locus_tag="OPY25_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCS0927964.1"
                     /translation="MTTLYLASGSPRRQELLIQLGFSFEQVVPGIEEQRRVQESAQQY
                     VVRLAREKAQAGVALVPRDLPVLGADTIVVLNGEVLEKPRDAAHAAEMLRLLSGNTHQ
                     VMTAVALADSQQTLDCLVVTEVTFRTLSAQDITGYVASGEPLDKAGAYGIQGRGGCFV
                     RKINGSYHAVVGLPLVETYELLSHFNALRDKRDKHDG"
     gene            complement(13124..13612)
                     /gene="mreD"
                     /locus_tag="OPY25_002363"
     CDS             complement(13124..13612)
                     /gene="mreD"
                     /locus_tag="OPY25_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCS0927965.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDDIIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRALSMSIVAYLVALKFQLFRNLALWQ
                     QALVVMLLSLAVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWLFLLMRKVRQQFA
                     VQ"
     gene            complement(13615..14667)
                     /gene="mreC"
                     /locus_tag="OPY25_002364"
     CDS             complement(13615..14667)
                     /gene="mreC"
                     /locus_tag="OPY25_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCS0927966.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGVIIADSRLGTFSQIRTYMDT
                     AVSPFYFISNGPRELLDSVSQTLASRDQLELENRALRQELLLKNSDLLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPPAPVPDPATGITQPSAGQTTPVSTQ
                     SSPSGATTPSARAPGG"
     gene            complement(14732..15775)
                     /gene="mreB"
                     /locus_tag="OPY25_002365"
     CDS             complement(14732..15775)
                     /gene="mreB"
                     /locus_tag="OPY25_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HCS0927967.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            complement(16083..18023)
                     /gene="csrD"
                     /locus_tag="OPY25_002366"
     CDS             complement(16083..18023)
                     /gene="csrD"
                     /locus_tag="OPY25_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HCS0927968.1"
                     /translation="MRLTTKFSAFITLLTGLTIFVTLIGCSLSFYNAVQYKYVSRVQA
                     TATAIDTHLVTHDIVSLTPQIDELMIASDIVRVDLLQGERSVYSHSRARGYRPAGTSD
                     MYRELVVPLIKHPGMSLRLVYQDPMGNYFHSLITTAPLTLAIGFIVLILFLSVRWLQR
                     QLSGQELLEIRSTRILNGERGANVRGSVYEWPARTSSALDVLLSEIQFAHEQRSRLDT
                     LIRSYAAQDTKTGLGNRLFFDNQLATLLEDQEKVGVHGVVMMIRLPDFNLLRDSLGGN
                     QAEEQMFMLINLLSTFIMRYPGSLLARYHRSDFAVLLPHRTLKEAESIAGQLLKAVDA
                     LPANKMLDRDDMVHIGICAWRSGQSTDQVMEHAEAAARNAALQGGNSWAIYDDTLPEK
                     GRGNVRWRTLIEQMLNRGGPRLYQKPAVTREGRVHHRELMCRIYDGKEEVSSAEYMPM
                     VLQFGLSEEYDRLQISRLITLLGYWPDENLAMQLTVESLIRPRFQRWLRDTLMQCEKS
                     QRNRIIIELAEADVCQHISRLQPILRLVNALGVRVAVTQAGLTLVSTSWIKALNVELL
                     KLHPSLVRNIEKRTENQLLVQSLVEACAGTPTQVYATGVRSRGEWQTLTKRGVAGGQG
                     DFFASSQLLDTNVKKYSQRYSV"
     gene            18227..19201
                     /locus_tag="OPY25_002367"
     CDS             18227..19201
                     /locus_tag="OPY25_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCS0927969.1"
                     /translation="MQALILEQQDGKTLASVQHLEESQLPAGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRHFPMIPGIDFAGTVHASEDPRFHAGQEVLLTGWGVGENHWGGLAERA
                     RVKGDWLVALPAGLSSRNAMIIGTAGFTAMLCVMALEDAGIRPQDGEVVVTGASGGVG
                     STAVALLHKLGYQVAAVSGRESTHGYLKSLGANRILSRDEFAESRPLEKQLWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFALPTTVMPFILRNVRLQGVDSVMTPPARRA
                     EAWARLVKDLPESFYAQAATEITLADAPKFADAIINNQVQGRTLVKIK"
     gene            19314..20318
                     /gene="msrP"
                     /locus_tag="OPY25_002368"
     CDS             19314..20318
                     /gene="msrP"
                     /locus_tag="OPY25_002368"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HCS0927970.1"
                     /translation="MKKIRPLTEADVTAESAFFMQRRQVLKALGISAAALSLPSTAQA
                     DLFSWFKGNDRPKAPAGKPLEFSQPAAWRSDLALTPEDKVTGYNNFYEFGLDKADPAA
                     NAGSLKTEPWTLKISGEVAKPFTLDYDDLTHRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LYKLLAQAQPTSHAKYVAFETLYAPDDMPGQKDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPIRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLSAPNEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYANEVASLYRGLNLRENF
                     "
     gene            20319..20918
                     /gene="msrQ"
                     /locus_tag="OPY25_002369"
     CDS             20319..20918
                     /gene="msrQ"
                     /locus_tag="OPY25_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HCS0927971.1"
                     /translation="MRLTVKQITWLKVCLHLAGFLPLLWLFWAINHGGLSADPVKDIQ
                     HFTGRTALKFLLATLLVSPLARYAKQPLLIRTRRLLGLWCFVWATLHLTSYALLELGI
                     HNLALLGSELISRPYLTLGIISWLVLLALTLTSTQFAQRKLGKRWQTLHNVVYLVAIL
                     APIHYLWSVKILSPQPVIYAALALALLALRYRKFRQWWR"
     gene            21312..21782
                     /gene="accB"
                     /locus_tag="OPY25_002370"
                     /gene_synonym="fabE"
     CDS             21312..21782
                     /gene="accB"
                     /locus_tag="OPY25_002370"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCS0927972.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRTTANAGFPVM
                     QQAYAAPMMQQPALSNAVAPAATPAMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKAGTVKAILVESGQPVEFDEPLVVIE"
     gene            21793..23142
                     /gene="accC"
                     /locus_tag="OPY25_002371"
     CDS             21793..23142
                     /gene="accC"
                     /locus_tag="OPY25_002371"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCS0927973.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKADTIRLMGDKVSAITAMKKAGVPTVPGSDGPLGDDMNANRAHAKRIGYPVIIKA
                     SGGGGGRGMRVVRSDAELAQSISMTKAEAKAAFSNDMVYMEKYLENPRHIEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSITQDEVVVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNIDLQTRIMNDEHFQHGGTNIHYLEKKLGLQEK"
     gene            23251..23493
                     /locus_tag="OPY25_002372"
     CDS             23251..23493
                     /locus_tag="OPY25_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HCS0927974.1"
                     /translation="MDARFVQAHKEARWALWLTLCYLAAWLVAAYLSGDSPGITGLPH
                     WFEMACLLTPLVFILLCWAMVKFIYRDIPLEDDDAA"
     gene            23483..24934
                     /gene="panF"
                     /locus_tag="OPY25_002373"
     CDS             23483..24934
                     /gene="panF"
                     /locus_tag="OPY25_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HCS0927975.1"
                     /translation="MQLEVILPLVAYLVVVFGVSIYAMRKRTAGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFIGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGVSIALYTAFGGFRASVLNDTLQGLVMLVGTIVLLVGVVHAAGGLHQAVDTLH
                     ALDPKLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVLPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNLRPDQMQNEIRLKRMSAAITLLLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAAGALSAMIVGGVLYALLATFNIQYLGFH
                     PIVPALLLSLLAFLIGNRFGSSASQATVLSTDK"
     gene            24946..25827
                     /gene="prmA"
                     /locus_tag="OPY25_002374"
     CDS             24946..25827
                     /gene="prmA"
                     /locus_tag="OPY25_002374"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCS0927976.1"
                     /translation="MPWIQLKLNTTGANAEELSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMKDVVAILEQHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDIPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEAMKADVVVANILAGPLRELAPLISVLPVEGGLLGLSGILASQAESVCDAYAELFTL
                     DPVVEKEEWCRITGRKK"
BASE COUNT         6203 a         7364 c         6791 g         6008 t
ORIGIN      
        1 tagtgtatac ttaattttgt gatgagggtc acgaaacaaa gaccccagta aaggaattcg
       61 acgaggtaaa aatcatgaaa atcaaaacca ctgttgcaac attaagcatt ctgtccgttc
      121 tctcttttgg cgctttcgcc gcagaaccta tcagcgcaga gcaagcgcaa aaccgtgaag
      181 caatcggatc ggtttcagtc agcgctatcg gctcatcgcc tatggatatg aatgccatgc
      241 tgagcaaaaa agcagatgaa caaggcgcta cggcctacca cattaccgaa gcgcgtagcg
      301 gcagcaactg gcacgccact gccgaactgt acaaataaaa ttcacctgcc atcgcatata
      361 acgtgtcgtt acttcgcgga gatatcgcat aagaaaagcc cattaatccg cgaggttgac
      421 cctataaagg aataaaagac catgaaaacg aaatacatta tcgcatcact cggcctggcc
      481 actctgctct ctttcggcgc aaatgccgca gtacaccagg ttaacgcgga acaggcgcag
      541 aatctgcaac cgatgggcac catttccgtc tcgcagattg gcagtacgcc aatggatatg
      601 cgccaggaga tcgtcgctaa agccgaaaaa gcaggcgcta atagctatcg catcatcgaa
      661 ttaaaagaag gtgataactg gcacgccacc gccgagttgt ataagtaaac cttcgtcgtc
      721 taacccgacg acttgccccc gcatgccggg ggctttttta tgctttttca atgccggaca
      781 ttaaaccgta gccgtccctc cagctcttct tccgcttcat caaagagtaa aatcagcgcc
      841 ccgtagcgcc tgcgcagttt atcaggcagg tgaacgaact caatctctag cggtaggggt
      901 aagatatcgc tcattaccgc atcccataat gtatcaagat cgcttacttt ctcactggca
      961 aggccaaacg tctgcgtaaa ctcgcgataa aaatcgcttt ggtttttaat atcattaaaa
     1021 tcaaatgtat agacattcat agccagccac catccccgac agacaattgt ctgttttact
     1081 actaagcatc attatgcaga ggtttcactt ccagaaacgc ttttagcccc ggagcactct
     1141 tgcgctgttt ttgtatctca aataagtata gtcataaaaa aaccgacgct tttggcatcg
     1201 gttcttgtgg attagctatc ggtaagcgcg ttctggtatt tatgtaacat gcccgtcagg
     1261 cgtttaaccg gttccgtcac ctgcggcggc gcctcccaga tacgtaattt ctcctgatag
     1321 atatccagct catccagcaa ctgaccaaag tagcgtcgcc gtttatcatc gcttccggcg
     1381 gaaataacat agtctgcggt acgacgaagc tggcggtgga acactgacag atcttcatta
     1441 accggtatcg gcgcgtcgcg cagacgttga tgagcaatga tcatcgttag cgccaggcgg
     1501 aacttcggca aatcgcctgg gaatttattc atcagcaaaa agagttgctg atataacgca
     1561 ggcagacggt tttctttacg gcgtaccacg ttggtcgtca ttgccgagac cgcagcggaa
     1621 acaaactgat taagcagcac gcgaccggtt cgatctttgg atttatcacg caccagcagg
     1681 atgacgataa acgccagcat acagccgaca atttgcccca acgcgctgtc gaggaactgg
     1741 atgaaatgga acgtcatcgg attatccaac acaataatgt taatcgtact ggccagcgcc
     1801 cccatcgacc ccagacgccg tttctgaact tcaataccga taaagaaccc caataccgcc
     1861 aggctcaaac ataacaacag catactttgc tgcgtattgg gaataatcac caggaaatag
     1921 agcaatccca gcggcaacgc cgccagagtg ccataaataa aatcaatgca gaccatgcgc
     1981 ggattgggta aacgcatcgc cagcgaggtc accacggcaa tcatcaccat cgcgccatta
     2041 cccgatgtcc agccggtcca tagccagaat aatgtcccca gaatgcagga aagcgtggtg
     2101 cgccagaagt tcaccatcgc atggtggcgt tcagcggatt ccactttaac tacgggctcg
     2161 ccttgcagga tctcttcttc cgtcgcgctg attttggtgt tactgatcac gccgcgttta
     2221 agcaacagat agcgcgttgc agcgcctacc cagctataaa gcgtgacggg cgtttcgcgc
     2281 tcgccggtcc aaacaatgac acgccgcatc cgttttaact gcctgtggac gtcctgtacc
     2341 gtttcaaccg gcgtctcgaa cagttcccgg aatgtatcgg taatcagttc cggccgcgtg
     2401 ttttgaataa gataagtttc acaggattgc gtaatcagcg tgagcgaaag cgtattcaac
     2461 gctttcaggc ggcggttagc gcgtacccag cgcgaagatt ccatattcag attacttcgc
     2521 atcccctcca gcgccgccgt gcgtcgcacc agatcgcccc aggcgttgtc gacttcttcg
     2581 ctgtcgccat gcttaataca aagttgcatt agctgatatt gcgctaccag taaacagtcc
     2641 agttcgcgat caacctcctg ctttatcgat cgcggcgaga aaagcagatc cgctaaaata
     2701 gcgcagccaa tgccgatgac gatttcgcta cagcgctcaa gcgcaaattg cggcgtaagc
     2761 agcggctccg tctgaatggt aatcacaatg atcagcgcag tataacctga cagtccccac
     2821 gcataagagt tttcgatccg tactaaagag gagatccagg tacaaaaacc ggcccagaca
     2881 cagcacacca gaatcatcaa tagcggcgcg cggatcatag agataataat gataagcgcg
     2941 gcgatacagc caataaacgt cccgataata cgcaacattc cgcgataacg gatagcgccg
     3001 gaatagggtt ccccgccggc ggcaaatgcc gggcctgccg ccacgatcgc ggcggtcagc
     3061 accgcccaac gcggcgtctc cagctgaaaa tggaagccga taaataatgc cagcacaatg
     3121 gcgcacgcca gctttaccgc aaaacgaatg tgctggttgg caatggagaa aatgcccatg
     3181 acgattaacc gaattcgcgc agccggtgcg ccagtttacg gaagaaggag tcctggcttg
     3241 cgtcacgatc ctgcttaccg gtgatcacga cggttgccgt cgtaccggca ggccacaaat
     3301 tcccctgctg ctcgtcgagc cggatgcgca ccgggacacg ctgggccaga cgcacccatt
     3361 cgaggttaga gtctatcgtc gccatccctt tcgcatcgct ggtactgctg gcattcgtta
     3421 cccctgccgc cacgctatcg acggtgcctt ttaatacccg gttgctgccg agcggcgtga
     3481 tttcggcacg atatcccgga cgcacgcctt ccagcttggt ctcttccata taggcctgca
     3541 cgtaaaaaga gttctttttc accagggcga cggctgtgga accgcgggta ataaattcac
     3601 cggcataaac attgaggtta gttacccagc cgtctgcagg cgcacgaatg acggtacgct
     3661 ccagatcgag tttagccaga tcgcgcgtcg cctgggcttt agccaattga tgcagtaccg
     3721 tctgcaagac gttgttcgcc tgatcgatct cttcccggga catcgcctgt acgccgaggc
     3781 gattacggcg accggcttcc tggcgttttt cctgcgccag tacctgataa taggctacat
     3841 cagcttccgc ttccgccagc gctttttgat agcgtggctg atcgatggta aacaggacct
     3901 gatccttttt caccagttgg ttatcatgca cgtttacatg ggtaatcagg cccgcgacat
     3961 ccggggcaat agcgacgaca tcggcgctaa aacgcgcgtc gcgcgtccag ggtgattcgg
     4021 tgtaatacac ccaggcgcgg aaaatggcga taaaggccag aataaccagt acgagggtaa
     4081 tggccgtacg ggagagtttt cttgttagtg ttttcacttc aacctcaaac gaacaggcgc
     4141 gatattaaat aaaacagaca acaatacagc gcggtattga acagagccgg atgccagaca
     4201 aaatcataga tgcccgtcgg cacaagcatc cgacgcacca gccaaaaaat agccagtgac
     4261 aaaagcaatt cgaaaaatat cggtgggaag gaaagaccaa acaccacgat aacgggaaac
     4321 agactcatgt tgaccttgat ttctgagaga gagcaggcga tagattgtta agctacatcg
     4381 ccgcagagaa gggcaagaga cgccaggcga gagcgacata gctcttattc gaataatagt
     4441 atattaacgt aattgttatg ctgttatcta tattatgtga tctaaatcac ttttaagcca
     4501 gagtgaataa tggaacgatt aaaacgaatg tcggtattcg ccaaagttgt tgagtttggc
     4561 tcttttaccg ccgcagccag acagctgcaa atgagcgtat cgtccatcag ccagactgtg
     4621 gcgaaactgg aagatgagct tcaggttaaa ttgctcaacc gcagcacacg cagcattggg
     4681 ctcaccgaag ctggaaaaat ctattatcag ggctgtcgtc gtatgctgca tgaagtgcag
     4741 gatgttcacg agcagcttta cgcttttaat aacacgccta tcggtacatt gcgtatcggc
     4801 tgttcttcaa ccatggcgca aaatgtgctg gccgggctta ccgcaaaatt attaaaagag
     4861 tatcccggtc tggcggtcaa tctggtgaca ggaattccgg ccccggattt aattgccgac
     4921 gggctggacg tggtgatccg cgtgggcgcg ctgcaagact ccagcctgtt ttcccgtcga
     4981 ctcggcgcga tgccgatggt tgtgtgcgcc gccaagccct acctcgctca gtacggcgtc
     5041 ccggaaaaac ccgccgatct cagtagccat tcctggctgg aatatagcgt gcgcccggat
     5101 aatgagtttg aacttattgc gccggaagga atttctaccc gactgattcc acaggggcgg
     5161 ttcgtcacta acgatccgat gacgctggta cgctggctga ccgccggaac cggaatcgcc
     5221 tatgtgccgc tgatgtgggt gatcgatgag atcaatcgtg gcgatctgga gatcctgctg
     5281 cctcgctatc agtccgatcc ccgtccggtg tacgcgctgt acaccgaaaa agataagctg
     5341 ccgcttaaag tgcaggtagt gattaacgcg ttaactgact attttgtcga tgtcgcacac
     5401 ctgtttcagg ggatgcacgg gcgagggaaa gaaaaataaa aacaccgggt aattgctgaa
     5461 gacgattgta gatcagatgc cacccgaggc agacattgcc tgatggcgct gcgcttatca
     5521 ggcctgggcg gcacatacca caggcctgat aaggcggaca gttatgcggt gccgccaacc
     5581 gtcaggttat cgactttcag cgtcggctgg cctacgccta ccggcaggct ttggccctct
     5641 ttaccgcaga cccccacccc gttatccagc ttaaggtcgt tgccgaccat ggagatctgt
     5701 tgcatcgttt caatgcctga tccaatcaac gtcgcgccct tcaccggcgt cgtgactttg
     5761 ccgttttcaa tcagatacgc ttccgaggta gagaacacaa acttgccgga ggtgatatcc
     5821 acctgaccgc cgccaaagtt aggcgcatag atgccatact caacggattc gataatttcc
     5881 tgcggcgttg actgccccgc caacatataa gtattcgtca tacgcggcat cggcagatgc
     5941 gcataagatt cgcgacgccc gttaccggtc ggcgcagcgc ccatcaggcg cgcgttcagc
     6001 ttgtcctgca tgtatccttt cagcacgcca ttttcaatca atacgttgta ctggcctggc
     6061 gtaccttcat catcgatagc aacggagcca cgacggttca tcattgtgcc gtcatccact
     6121 acggtgcaaa gcgcggaggc aacctgctca ccgatctgac cgctaaacac agacgtccca
     6181 cgacggttga aatcaccttc cagcccgtgc ccgaccgctt cgtgcagcaa tacgcccggc
     6241 cacccggcgc ccagaaccac cggtaacgtc cccgctggcg cagcgaccgc ggagagatta
     6301 accagcgcca tgcgtaccgc ttctttcgcc cacgcgtcgg cgcgcacctc gccgtcaaga
     6361 tcggcaagaa aatactcata accaaagcga ccgccgccgc cgctggcgcc gcgctcgcgt
     6421 ttaccgtctt cttccacctg cacgctaacg gacaaacgca ccagtggacg gacatccgcc
     6481 gccagcgtcc cgtcggtcgc cgccacgagg attaattcat atacgccggt caggctggcg
     6541 ttaacttcct gcacgcgttt atcggcttct cgcgccgctt tatcaacgcg tctgaggata
     6601 tccagcttct cttcgcggct catactttgc agcggatcaa gggtggtgta gagcggctga
     6661 tgcgctacgg cggcgagcgt ttttaccttg ccttcgccgt tctcgcgtac aatggttcgc
     6721 gctgcctgcg cactctgctc cagcgcaagg aggcttatct ggtcagcata agcaaaaccg
     6781 gttttttcgc cgctaatggc gcgaacgcca acgccctggt cgatattata tgaaccatct
     6841 ttaatgatgc ggtcttctaa aacccaggat tcgtgatagc tcgactgaaa atagaggtcg
     6901 ccataatcaa gacggcgttc ggccagttgg cccaaaatag cgaacagatc ctgatggttc
     6961 aggccattcg ccgctagcaa ttgttcactt accaggttca gactcatcgt ttttgctact
     7021 cgttgatttc tgccggatgg cggttcacgc cttatccgga ctacgttgtt agattgtgca
     7081 aaccggataa acgcagcgcc gtccggcatg actatttact gagagtgggg caattcctcg
     7141 cccccgtcaa atcattgctg gctttctttt ctcggttggc gcagaacttc gttgatctgc
     7201 ggcgcatcga ccggaccggt aatgcgataa cgcagaatgg agaccttgct ccatagcggc
     7261 cccaacactt tactggcggc aaataccgcc gcgccgacaa tcgggttaac ggcaaacgcg
     7321 gcagcgacgc ccacggtggc ggaaatttcc gccgcgacaa cggcctccat atcaagacga
     7381 cgacgcacca gatcaacaga acctttcatt gcaatatccg cttccagccc atccaccagc
     7441 gtatcgtcag tatgcaggac gccatcttta atccacgcgg tactatgaat agagtcgaaa
     7501 tagaagccct cgctaaaggt atctctgaag tcaaaccgca gcttacgcag caacgcatca
     7561 aaactgagca gccgcagtag ctgtccggca tgaccgctac tgagatcagt aaactcgcct
     7621 ttgcccagac gcgtacgtaa aatcccgttg agcgtggctt cctcaggttg ccagggcggg
     7681 tttcgccagt gcagatcgta atctacgtta aaagacgcgt tctggattgg cgtcgagatg
     7741 ccgaagaacc cggcagccgt gtcgaggtta ctaccatgca gactaccttt cagcgaggtt
     7801 cgttcattac ccggcgcatt cacccactcg ccgttcgctt tcaaacgggc gaatccggta
     7861 tcgatcaggc cattcgccag agtcagcgta ttgcctttga tggcgaaatc gccatcaata
     7921 cgcccatatt tttgccccca tagccagcac tcttcgcagc gaagctgtaa gtccggccag
     7981 ccgcggaagc taatcgtgtt cgccgaagcc aacggcgatg tcggcgttgg tgacgaggcg
     8041 tgcgtttttg cgacgccagg gttgtagtac aggtacttaa tgttcgccag ccacggcgca
     8101 tggttgcgca tgagtagcgt ggcgttcacc tcacggccct gcgcttcaat ttttgttccg
     8161 ttcagcgagg gggctgaaac gacgctcaaa ttgttccact gctggccgcc cagcgatagc
     8221 gcgggagtac gcaacgtgac gcgttgagga aactcggccg aactgctcac gttatccgcc
     8281 gcgcctttct ggaataacgc cagccattgc gcgccatcca gcgccggcag attgagctca
     8341 acgccttgtt gagcaggtaa tggcggaatc gtccggctgt ccgtcgtcca gatagcccga
     8401 tccaacgtca gcttctgatt taataaccag cggctgttaa agtgattttt actccctgcg
     8461 ctccccgtta gcgcaaaact tttcaggttg ccgtcagcct gaatgttcac cggaatggct
     8521 tcgcctgcgg gtttatttag cggagaaggt aagtgactgc tcacatttct cagatcgccg
     8581 ttcagctcga tgtgataagt ggtgtcagcg tgatatggaa gatcgatgcc gactttacca
     8641 ttccacgtca cgctgccgct cagggcgtca ttcagttgcg gcggtaagac gcccatacgc
     8701 gttggctgcc agttaccgtt caggttgacg gcgacctgat aggcttttgc cccttccgtc
     8761 gtactgaaat ccaggttaag cggctgatta aaccagtttg ccgtcagtgg cccgcttttt
     8821 agcgcgccat tcacaaagct gaatttaccg ttcagatttt tgagcgtgct gtttagcggc
     8881 ttaataaaca gactgttatt acgcaacgag acatcgccct cggcggtaac ctgttctccg
     8941 tccagcggaa tatcaagatg taagcgagca ttcacatcgc catctaattg gagctccgcc
     9001 agcgtcgagc caagcgagtc ttttagcggc gtctcgtcaa aataaggccc aacggctttt
     9061 cccggcccgt taatatcggc atcaatgagc agtttctctt tggaataatc cggaatcgcc
     9121 gccgcgagtt tgctggcctt caccccgccc aaatcgacgc tatccgaacg catccacagg
     9181 ccgtcgttca ggaaatccag ttcaatgttg agatttttta gcgccggcca gtcgggttga
     9241 aaagcaaacg tcgcattgcg tagcggcacc agcacttcaa actgaccttc gttatgctta
     9301 tagggaaaga ggtgcgggtt accaccgtaa accaacgtgg cgttatccgc ctcgccgccc
     9361 tgaatcgcgc cgctaaggta atcgactagc gctttgccca tcaggttttc cggaaaatag
     9421 cgccacgcct gagatccatc atcggtactg attccggcca gaatacccag ccacggttcg
     9481 tcgcccgtcg gttgcagata gcggaacccg ccgcgcgcat gtaccgcctt tgctttgacg
     9541 tcaatgtcgc ggccatcaag ctgaaagccg ttctcattct tcaaccagct aagcgtcgcg
     9601 acgccgtttt caatttccag cggcgcgcga aaaacggttt catagggcat cttagcctgc
     9661 tgcatcgcaa ccttcatctg cccgtcttct acgcttcccg ccagcgtacc ggaaaaatgt
     9721 tccgcgccgg gcaacagctt ccactgtttc caggcaagat tttcccacga tgcctgaaaa
     9781 cgcgtttttt cggtcgcctg tagcggaata tccagcgcca gtgtggcgat ctttccgctc
     9841 ggctgcgtag cctgccatat ttcgcccagc acaggcgaca gtttagccgc cagcggacgt
     9901 aatgcttcca gccccgccag ttcaagatta ctggcgcgaa tgcgtagctc atcgctacgt
     9961 gtgtgattct cgccgccgac gtcctgctgc gggagccagg ccacggttaa ggctccgctc
    10021 ggccagggtt tgccatcaag cgtaatccgt gtgtccggaa tataaaactg ccagcccggc
    10081 tgctcgcggc taatctgcgc cgtcaggtta tcgacagaca acgtatgcgt cgtgttatcg
    10141 cccagccagc ttgcgccgcc ctgtttcagc cagacgtccc ctccggcgat ttcgccttta
    10201 ctgagcgtca tccagccttc cagactgaaa cgcgccgtct ggagcgccac attatcctgc
    10261 atccatttgc ccagccacgg cttgacgtca atatcgtcgg cctgtaacca gactctgccg
    10321 ttatttagca gaccgtcgtc atcgcgtaaa tccatccgca cctgcatcac gccgtgctgc
    10381 ccggtcaggc tggagaggct gacctcgcct tcggctcggt gccgctcttt gccgtttagc
    10441 caggtaagtt gtgggatcgc cagttccgcg cgttgtcctg aaagcgtcag aaaactgatt
    10501 tggctatcgc gcagatcgaa atgatcgaac tgccgcagga aaagatcgct taaacggctg
    10561 gtttcgatgc cttcgccgtc gctgctttga agaggcgtgt tggtgcggaa attgagttgc
    10621 cagaaggtca ggtcgcgaaa ctgccagcgc atgtgcaaca ggctttgcca gacgtccagc
    10681 gccagcgtaa cgcgttttat cgacagctcg ccgccatctt tcagggcggc atgaatatta
    10741 tgcgcttcca gcgtagggcc aaaattttgc cagcttgcgg agagttggct ggcggccacc
    10801 ggcacgccgg tcacggactc aattttattc aggatagctg gacgccaggc gtcaagatga
    10861 ggcaacgcca ggcgcagccc gctaaccagc agcgctgcaa tgacgatgag cgcggctcca
    10921 gtgagcaata aaatccccgg caatcgcctc acgcgtctct ccttgtctgc caaaaaatac
    10981 gactcacccc ccttgagggt atattgccgg atggcggcgc ttgcgcctta tccggcctac
    11041 atgcgctggt gctattactc aattacatca ttacgacgtc aaactgctcc tggttataaa
    11101 gcggttcgac ctgaacttta acctgtttgc cgacaaagat ttcgacctcc gccagcgcgt
    11161 gtgattcttc gcctttcagc gcttccgcca ccgcaggaga agcataaacc aggaagcgat
    11221 cggagtcata agcgtgatga acacgtacaa tttcacgcat gatctcatag cagacggttt
    11281 ccaccgtttt taccgtcccg cggccatgac aggttggaca ctcgttacaa agcacatgtt
    11341 ccacgctttc acgggtccgt ttacgggtca tttccaccag tcccagcggc gaaaaaccgt
    11401 taatactggt tttcacgcga tccttactta acgcctgttc cagcgaatgc agcacccggc
    11461 ggcgatgatc ttcattattc atgtcgataa aatcgataat gataatgccg cccagattac
    11521 gcaggcgtag ctggcgggca atggcctgcg tcgcttcaat attggtatta aaaatggtgt
    11581 cgtcgagatt acggtgtccg acaaacgcgc cggtattgat atctaccgtc gtcatcgctt
    11641 cggtttggtc gataatcaga taaccgccag acttgagttc aactttacgc tccagcgcgc
    11701 gctggatttc attttccacg tcataaagat cgaagatcgg ctgatggcca ctgtaatgct
    11761 ccagcttact ggtcatttcc gggatgtatt ctgcggtaaa ctccagcagc gactcatagg
    11821 tcagacgtga gtcgacgcga attcggtcca actgcgcatc ggcgaaatcg cgcagcacgc
    11881 gctgcgccag cgccagttcg ccatacatct ggtagcgcgt ttgcggacgc tttttgcgct
    11941 ccatgacttt cgtccagacg cgcttgagat aggcggcgtc agacgcgaga tcctcttcac
    12001 acacgccttc cgccgcggta cggataataa acccgccctg ttcgtcgcag tattccgcca
    12061 ccaccttttt caggcgctcg cgttcacttt cgctttcgat gcgctgggaa acgccaacgt
    12121 gtgacgcgcc gggcataaaa acaaggtaac gggagggcaa cgtgatgtcc gtggtcaaac
    12181 gcgcgccttt cgtgccgagc ggatctttca ctacctgcac catcagatcc tgtccctgac
    12241 gcaccagttc ggagatatcg cgcacggtaa actgtttttg ctcgtcgccc gccacgcatt
    12301 cggtatgcgg cataatgtcg gaagcgtgaa gaaatgcggc tttatccagc ccaatatcta
    12361 caaaagccgc ctgcatacct ggaagtacac gacttacacg acctttgtag atattgccta
    12421 cgattccgcg tcgcgcttcg cgctcaatat ggatttcctg aagaataccg ccatcaatgt
    12481 acgccacgcg cgtttccgat ggcgttacgt ttaccaacaa ttcagccgtc atgtttatcc
    12541 cttttatcac gcagtgcgtt aaaatgactc aacaactcat acgtttcaac cagcggtaag
    12601 ccgaccacgg cgtgatagct gccatttatc ttcctgacaa aacagccacc ccgcccctga
    12661 ataccgtatg cacctgcttt atctaaaggc tcgccgctgg cgacatagcc agtaatatcc
    12721 tgcgcagaaa gcgtgcggaa agtcacctcc gttaccacca gacaatccag cgtctgctgc
    12781 gagtccgcaa gcgcaacagc agtcatcacc tgatgcgtat ttccggaaag caaacgcagc
    12841 atttctgcgg catgagcggc gtcgcgcggc ttttccagca cctcgccgtt taacacgact
    12901 atcgtatccg cgcccaacac cggcagatca cggggaacca gcgccacgcc agcctgcgcc
    12961 ttttcgcgcg ccagccgaac aacatactgc tgcgcgcttt cctgaacacg ccgttgctct
    13021 tcaataccag gcacgacctg ctcgaatgaa aatccaagtt gaatcaataa ttcctggcga
    13081 cgcggggaac cggaagcaag atacagagtt gtcatatcga cctttattgc acagcaaact
    13141 gctggcgtac tttacgcatc agcaaaaaga gccagggcca cagcacgcca ttgactacac
    13201 tactccagaa cacttccggt ctgaaagaga cgttgatcac taaaaactcg gcccagaaaa
    13261 caataatgtc cacggccagt gaaagcaaca ttaccaccag cgcctgctgc cagagcgcca
    13321 ggttacggaa gagctggaat ttcagagcga ccagataggc gacaatgctc atcgacagag
    13381 cgcgcacgcc aagtgtggaa ccgctgatga gatcaagtat ggcacccatc acaaatcccg
    13441 tccccacatt tacgcggtgc ggcagggcca gaatccagta cagtaagatg agcaaaaccc
    13501 agtttggccg gaaaacaatg atgtcgtccg gccagggcat gatttgcagc aacagcgcaa
    13561 taagaaacga gagccagata acccagcgcc cctggctacg atagctcgcc accattaccc
    13621 tcccggcgca cgcgcagacg gcgtggtcgc gcccgaaggc gatgattgcg ttgataccgg
    13681 cgtagtctgg cccgcagatg gctgagtaat ccccgtcgcc gggtccggca ctggcgccgg
    13741 cggccccatc gcatccggag aaggtaacac ctgcggcatc atctgcatca ggcgctcatt
    13801 ggcgacgcgg tgaacctctt ccggcgtcat cggattggcg ccgttacgat cggctcccca
    13861 caacagcagc agatagcgta aacgctgcaa acccgcggtt ggacgagcct gaatgacggt
    13921 ataggcgcgc tgagtgtcca gcttgacgga ggagaccacc gccaccggat acccttccgg
    13981 gaaacgccca ccaagtccgg acgttaccag cacatcgcca acgcgaatat cggtattggc
    14041 gggcagatgt tcaagctgaa gatcgtcagt gcagccgtta ccggcggcaa tcacgcggat
    14101 gtcattgcgt agtacctgaa tcggcagagc atgagtcgca tcgcaaatca gcaatacgcg
    14161 gctggtcagt ttcgccacgg cgacaacctg ccctacgaca cctttgtcgc taatgaccgg
    14221 ttgaccttca tatacgccat taacgctgcc tttatcgata acgacctgat cgctgtaagg
    14281 atcgttaacc gttgaaataa cctgcgtcac cattttctgc tcgtcctgac gcagcggcga
    14341 ccccagcagc tcgcgcaacc gcgcgttctc ctgtttgtac tgccccagca tcagcaggtc
    14401 gctgtttttt agcagtaatt cctggcgcag cgcccggttt tccagctcaa gctggtcgcg
    14461 agaagccagc gtttgcgaca cgctgtcgag cagttcacga gggccgtttg aaataaaata
    14521 gaaaggactg acggcagtgt ccatgtacgt tcggatttga ctgaacgtcc ccaggcggct
    14581 gtcggcaatg ataacgccga gcgccaccag caccgccaga ataaggcgaa tctgtagcga
    14641 cgggccacgg ctaaaaattg gcttcatagg ctatgcgtat tctcgcgtcg gagaggcagg
    14701 acaatccagg gataatcctg cccgtatcca actactcttc gctgaacagg tcgccgccgt
    14761 gcatatcgat catttccagc gccttgccgc cgccgcgcgc cacacaggtc agcggatctt
    14821 cagcaaccac gacaggaatg cccgtctctt ccattaacag acggtcaagg ttacgcagca
    14881 gcgcgccgcc gccggtgagc accataccgc gctcggagat gtctgacgcc agctccggcg
    14941 gacactgttc cagcgccacc attaccgcgc tgacgatacc ggtcaacggt tcctgcaacg
    15001 cttccagaat ctcgtttgag ttcagggtaa agccgcgtgg aacgccttcc gccaggttac
    15061 ggccacgcac ttcgatctcg cggacttcgt cgcccggata agcggaaccg atttcgtgtt
    15121 taatacgttc tgcggtggct tcaccaatca gagaaccgta gttacgacga acgtaattaa
    15181 tgatggcttc gtcgaagcgg tcaccaccaa tacggacaga agaagagtaa accacgccgt
    15241 tcagggagat cacggcaact tcagtggtac caccaccgat atccacaacc attgaaccgg
    15301 ttgcttcaga aactggcaga cctgcgccga tcgcggccgc catcggctct tcgatcaaaa
    15361 agacttcacg ggcgcctgcg ccctgagcgg attcacgaat cgcgcggcgt tctacctgcg
    15421 tcgcgccgac cggcacgcat accagtacgc gcgggcttgg gcgcataaag ctgttgctgt
    15481 gcacttgttt aataaagtgc tggagcattt tttcggtcac aaagaagtca gcgataacgc
    15541 catctttcat cggacggatc gcagcgatat tgcccggcgt acggcccagc atctgcttcg
    15601 catcatgacc gactgcagcc acgcttttcg gcgaaccggc acgatcctga cgaatggcca
    15661 caacggaagg ctcattcaat acgatgcctt gtccttttac ataaatgagg gtattcgcgg
    15721 tacccaggtc aatggacagg tcattggaaa acatgccacg aaattttttc aacatactaa
    15781 gggataatcc tgaaagctgg ggcggaaaac aaaatccgct tactttacca accacacgca
    15841 gcagcgacaa ggcgcaaaaa tcatctgcta cggtgaaaat tagtgcagtt cgtttccttt
    15901 gttacaaatc tcggcctgag tccctcaggg ctgaaaaaat cagcagcaat cctcgccttc
    15961 gtttgcaacc tgtcaaaggt cattcacctg catatttgct gcaacaatct ggcgagcaga
    16021 caagcacacc cccatgaggc gcagcgcgcg ttattctacg tgaaaacaaa ttaaacggca
    16081 ggttaaaccg agtatctttg cgaatatttt ttcacgtttg tgtcaagtag ttgggaggag
    16141 gcaaaaaaat caccctgccc gccagccacg ccgcgttttg tcagcgtctg ccactcgccg
    16201 cgcgaacgga cgcccgtcgc gtaaacctgc gtaggcgtgc ccgcgcaggc ctctaccaga
    16261 ctttgaacca gaagctggtt ttccgttcgc ttctcaatgt ttctgaccag actcggatgc
    16321 agcttgagta attccacatt gagcgcttta atccagctcg tgctaaccag cgtcaaaccc
    16381 gcctgtgtca ccgccacccg aacgccaagc gcattgacta agcgaaggat gggttgtaac
    16441 cggctgatgt gttgacaaac atctgcctcc gcaagttcaa taattatgcg atttcgctgt
    16501 gatttttcac actgcattaa cgtatcgcgc aaccagcgct gaaaacgcgg acgaatcagc
    16561 gactcaaccg tcaactgcat tgccagattt tcatccggcc agtagcccag caacgtaatc
    16621 aggcggctaa tttgtaatct gtcatactct tccgataaac caaattgcaa caccatcggc
    16681 atatactccg ccgagctcac ctcttcttta ccgtcataga tgcgacacat caattcccga
    16741 tgatgtacgc gaccttctcg cgtgaccgcc ggtttttgat aaagtcgcgg tccgccccgg
    16801 ttcagcatct gctcaatcaa tgtgcgccag cgcacattgc cgcgcccttt ttccggcaga
    16861 gtgtcgtcgt agatagccca gctatttccc ccctgcaggg cggcattccg cgccgcggct
    16921 tcagcatgtt ccatcacctg atcggtggac tgtccgctgc gccaggcgca aatgccgata
    16981 tgtaccatat cgtcacgatc gagcattttg ttagccggta gcgcatcgac agcttttaaa
    17041 agttgtccgg caatactttc cgcttctttc agcgttcgat gcggtagcag cacggcaaag
    17101 tcgctgcggt gataacgcgc cagcagcgag cctgggtaac gcataatgaa tgtcgatagc
    17161 agattgataa gcataaacat ctgctcttcc gcctgattgc ctcccaggct gtcgcgcaga
    17221 agattgaagt ctggcaagcg gatcatcatc accacgccat gcactcccac tttttcctga
    17281 tcttccagca gcgtcgccag ctggttatca aagaacagac ggttaccgag tccggttttg
    17341 gtgtcctgcg cggcgtagga gcgaatgagg gtgtccaggc gactacgctg ttcgtgagca
    17401 aactgaattt cggaaagcaa tacatcaagc gcgctactgg tgcgcgctgg ccattcgtaa
    17461 acagaaccgc ggacattcgc cccgcgttcg ccgttcagaa tacgcgttga gcgaatttcc
    17521 agaagctcct gcccggaaag ctgccgctgc agccagcgca ccgataaaaa caaaatcaga
    17581 acgataaaac cgatcgccag cgtcagcggc gccgtggtga tcagtgagtg aaaataatta
    17641 cccatcgggt cctgataaac cagacgtagc gacattcctg gatgttttat cagcggtacg
    17701 accagctcgc gatacatgtc gctggtgccg gctggccgat aacctctggc gcgagaatgg
    17761 ctgtagacgc tgcgctcccc ctgcaacaga tcgacacgca caatatcgga agcgatcatg
    17821 agctcgtcga tttgcggcgt cagcgagaca atatcatggg tcaccaggtg cgtatcaatg
    17881 gctgttgccg tcgcctgcac acggctgaca tacttatact gtacggcgtt ataaaagctt
    17941 agcgagcaac ctatcagagt cacgaagatc gttaatcccg tgagcagcgt gataaaagct
    18001 gagaatttcg tcgttaatcg catccttgag ttaactccga cggttataaa cagtatgaaa
    18061 aagcgaatct gaaggcggaa ttcgccacgg cgcgcaatga agcaggcata ctaccaaaat
    18121 ggatctatct ggcaatttat tgcgttgcat cggcatcacg ttttaattag cgagtatagt
    18181 cttcgtagct atttttccaa tctaccatgt aaagtgagga caggttatgc aggcgttgat
    18241 cttagaacag caggacggta aaaccctcgc atccgtgcaa catctcgaag agagtcaact
    18301 gccggcaggt gatgtgacgg tggatgtcca ctggtccagc ctgaattata aagatgctct
    18361 ggctatcacc ggaaaaggga aaattatccg tcattttccg atgattcctg gtattgattt
    18421 cgccggcacc gttcacgcaa gcgaagatcc tcgctttcat gcaggccagg aagtactact
    18481 gactggctgg ggcgtgggcg aaaaccactg gggcggcctg gccgaacgcg cacgcgttaa
    18541 aggcgactgg ctggtcgcgc tgcctgcggg actgagcagc cgtaacgcca tgatcatcgg
    18601 caccgccggt tttaccgcca tgctgtgcgt catggcgctt gaagatgcag gtattcgccc
    18661 gcaagacggt gaggttgtcg tcaccggcgc cagcggcggt gtgggcagca ctgccgttgc
    18721 attactgcat aagctgggct atcaggttgc agcagtatca ggacgtgaaa gcacccacgg
    18781 ctatcttaag agcctgggag ctaaccgtat tctcagccgc gatgagtttg ctgaatctcg
    18841 cccgttggaa aaacagctgt gggccggtgc aattgatacc gttggcgata aagtgctggc
    18901 gaaagtcctg gcacagatga actatggcgg ttgcgtggcc gcctgcggcc tggcgggcgg
    18961 cttcgcgctg ccgaccaccg ttatgccatt cattctgcgt aatgtgcgtt tgcaaggggt
    19021 ggactcggtg atgaccccac cggcacgtcg cgcagaagcc tgggcgcgtt tggttaagga
    19081 tctgccggaa tcgttctatg ctcaggccgc cacagagatt acgctggcgg atgcgccgaa
    19141 gttcgccgat gccatcatca ataatcaggt tcagggccgt acgctggtga agataaaata
    19201 acgtcacgta taaaaaaatt tacacttaat tacctattta tttttacaca ttgacacact
    19261 ccctattata ttcactacac gccatgttgt ggtgggtaga ccgggagtct gtgatgaaaa
    19321 agatacgtcc attaacagaa gccgatgtga ctgcggaatc ggcttttttt atgcagcgcc
    19381 gacaggtgct aaaagcatta ggcatcagcg cggccgcctt atccttaccc tcaacggcgc
    19441 aggccgatct cttcagttgg tttaaaggca acgatcgtcc gaaagcgcct gccggtaaac
    19501 cgcttgagtt tagtcagcct gccgcctggc gaagcgattt agcgttaacg ccggaagata
    19561 aggtgacggg ctacaacaat ttctatgagt ttggccttga taaagccgac ccggcggcca
    19621 atgccggaag tctgaaaacc gaaccgtgga cgttgaaaat cagcggggaa gtcgcgaaac
    19681 catttacgct ggattacgac gatttaacac atcgttttcc attagaagag cgtatctatc
    19741 gaatgcgctg cgtcgaagcg tggtccatgg tcgtgccgtg gattggtttc cctttatata
    19801 agctactcgc gcaggcacag cccaccagcc acgctaaata tgtggcattc gaaacactat
    19861 acgcgccgga tgatatgcca ggacagaaag atcgctttat tggcggcgga ctgaaatacc
    19921 cttatgtcga agggctacgt ctggacgaag ccatgcatcc gctgacgctg atgaccgttg
    19981 gcgtctatgg taaagcgtta cccccgcaaa acggcgcgcc cattcgcctc atcgttccat
    20041 ggaagtatgg ttttaaaggt attaaatcta ttgttagcat taaactcacc cgcgaacgtc
    20101 cgccaaccac ctggaatttg tcggctccca acgaatatgg tttttatgcc aatgtgaacc
    20161 cgcatgtgga tcatccacgc tggtctcagg ctaccgaacg ctttattggt tcaggcggta
    20221 tccttgatgt gcaaaggcag ccgacgctgc tgtttaacgg ctacgccaat gaagtcgctt
    20281 cgctgtatcg cggtctcaat ttgcgggaga atttttaagt gcgtctgaca gtaaaacaga
    20341 taacctggct aaaagtttgt ctgcatcttg ccggtttttt gccgcttctg tggctctttt
    20401 gggcgataaa tcacggtgga ctcagcgcag acccggtaaa ggatatccaa cactttaccg
    20461 gtagaaccgc gctcaaattt ttgctcgcca ccttgctggt ttcaccgctg gcgcgctacg
    20521 ctaaacagcc attattgata cgcacacgcc gcctgttagg attatggtgt ttcgtttggg
    20581 cgacactgca tttaaccagc tatgccttgc tggaactggg gatacataac ctggcgctgt
    20641 taggaagcga gttgatttca cgcccttatt tgacgcttgg gatcattagc tggctggtgt
    20701 tattggcgct gacgttgacc tcaacgcaat ttgcgcagcg taaattgggc aaacgctggc
    20761 aaacactgca taacgtcgtc tatcttgtcg cgatcctggc tcccatacat tacctgtggt
    20821 cggtaaagat tttatcaccg caaccggtca tctacgcggc attagcgtta gcccttttag
    20881 cgttgcgtta ccggaagttt cgccagtggt ggcgctagtt tggtgaactg tgcggtcgat
    20941 tgcaaaacgc aaaacaggta atgtcctttt tatgtttcgg gttgattatc ttccctgata
    21001 agaccagtat ttagctgcca attgcgacga aatagttata atgtgcgact ttacattccc
    21061 caacggcgat tttcgttcgc agataagggt gacaatcgtg caatgaaggt atattttgtt
    21121 ttttgcccga aaatggcaga agatagccac acaatgactg gcaaatcatg aatttcacct
    21181 tcgggtgcta cggcataaca ggcaaatcaa agatgcgcgg tattttaccc gcggcagtca
    21241 ttcacatgct ttacagacgg cgctaaaacg cctgtcacaa tcacactaaa caaagagtac
    21301 ggaacccact catggatatt cgtaagatta aaaaactgat cgagctggtt gaagaatcag
    21361 gtatctccga actggaaatt tctgaaggcg aagaatctgt tcgcatcagc cgcacaacgg
    21421 caaacgccgg tttcccggtg atgcagcagg cttatgcggc gccgatgatg cagcaacccg
    21481 ctctgtctaa cgctgtcgcg ccagcggcta ctccagcaat ggaagcgcct gccgcagcgg
    21541 aaatcagtgg tcacatcgta cgctccccaa tggttggtac tttctaccgc accccaagcc
    21601 cggacgcgaa agcgttcatc gaagtgggcc agaaagtgaa cgtgggcgat accctgtgca
    21661 tcgttgaagc catgaaaatg atgaaccaga tcgaagcaga caaagcaggc actgtgaaag
    21721 cgattctggt cgaaagtggt caaccggtag aatttgacga gccactggtc gtcatcgagt
    21781 aacgaggcga acatgttgga taaaattgtc atcgccaacc gcggcgagat cgcactacgt
    21841 attcttcgag cctgtaaaga actcggcatc aagaccgtcg ctgtgcactc aagcgcggat
    21901 cgcgatttaa aacacgtatt gctggcggat gagacggtct gtattggccc ggcaccgtcc
    21961 gtaaaaagtt atctgaacat cccggctatc attagcgccg ctgaaatcac cggcgcggtg
    22021 gcaatccacc cgggttacgg cttcctttct gagaacgcca attttgccga gcaggttgaa
    22081 cgctccggct ttatctttat cggcccgaaa gcggacacca tccgcctgat gggcgataaa
    22141 gtgtccgcga ttaccgcgat gaaaaaagcg ggcgtgccga ccgtaccagg atctgacggc
    22201 ccactgggcg acgatatgaa tgcgaaccgc gctcatgcca aacgtattgg ctatccggtg
    22261 atcatcaaag cgtccggcgg cggcggcggc cgcggtatgc gcgtggttcg tagcgatgct
    22321 gaactggcgc agtccatctc catgactaaa gcggaagcga aagcagcttt cagcaacgac
    22381 atggtataca tggaaaaata cctggaaaat ccacgccaca tcgaaattca ggtgctggcg
    22441 gacggccagg gcaacgctat ctatctggcg gaacgcgact gctccatgca gcgtcgccac
    22501 cagaaagtgg ttgaagaagc cccggcgcca ggcattacgc cggaactgcg tcgctatatc
    22561 ggcgaacgct gcgcgaaagc gtgcgtagac atcggctatc gcggcgcagg aacgttcgaa
    22621 ttcctgttcg aaaacggcga gttctatttc atcgaaatga acacccgtat tcaggttgaa
    22681 cacccggtaa ctgaaatgat taccggcgtc gatttgatca aagagcagtt gcgcatcgcg
    22741 gcgggtcagc cactgtcgat cacacaggac gaagttgtcg ttcgaggcca tgcggtagaa
    22801 tgccgtatca atgccgaaga tccgaacacc ttcctgccaa gccctggcaa aatcacgcgc
    22861 ttccatgcgc ctggcggctt tggcgttcgc tgggaatctc atatctacgc gggctacacg
    22921 gtgccgccgt actatgattc catgatcggc aaactcatct gctacggtga aaaccgcgac
    22981 gtggcgattg cccgtatgaa aaatgccctg caggaactga ttatcgatgg tatcaaaacc
    23041 aatatcgatc tgcagacccg catcatgaat gacgagcact tccagcacgg tggaaccaac
    23101 atccactatc tggagaaaaa actcggtctt caggaaaagt aatcgcacgt taatctcaaa
    23161 aggccggtga atccggcctt ttttatttct ggggatagcg atgccccatc atgtacaatt
    23221 cccgctttct tcacccataa gggacaaaaa atggacgctc gttttgttca ggcccataaa
    23281 gaggcgcgct gggcgctgtg gctgaccctt tgctatctgg cggcatggtt agtggctgct
    23341 tacttatctg gagactcgcc gggaattacc ggtctgccgc actggttcga gatggcctgc
    23401 ttattgacgc cgctggtctt tattttgctg tgctgggcga tggtgaaatt catttatcgc
    23461 gatattccgc tggaggatga cgatgcagct tgaggtcatt ctaccgctgg tagcctatct
    23521 ggtcgtggtc ttcggggtct cgatttacgc tatgcgcaag cgtaccgccg gcaccttttt
    23581 aaacgagtat tttcttggca gtcgttcgat gggcgggatc gtgctcgcga tgacgctgac
    23641 cgccacctat attagcgcca gttcatttat cggcggtccc ggcgcggctt ataaatatgg
    23701 tctgggctgg gtcttgctgg cgatgatcca gcttcccgcc gtctggcttt cactgggtat
    23761 tctgggtaaa aaattcgcta tcctggcgcg tcgctataat gccgtcacgc ttaacgatat
    23821 gctattcgct cgttaccaaa gccgcctgct ggtgtggtta gcaagcctga gtttattggt
    23881 cgcgtttatt ggcgcaatga ccgtacaatt tatcggcggc gcgcgactac tggaaaccgc
    23941 ggcgggaatt ccctacgaaa ccggcctgct aatatttggc gtcagtatcg cactctatac
    24001 ggcgtttggc ggctttcgcg ccagcgtact taacgatacg ctacagggcc tggtgatgct
    24061 ggtcggcacg atagtgctgc tggtgggcgt ggtgcatgcg gcgggcggtt tacatcaggc
    24121 cgttgacacg ctgcacgctc tcgaccccaa actggtaacg ccgcagggcg ccgatgacat
    24181 actttctccc gcttttatga cctctttttg ggtactggtc tgttttggcg tgattggcct
    24241 gccgcatacg gcagtgcgct gcatttctta taaagacagt aaagcggtac accggggcat
    24301 tattatcggt acgattgtcg tggcgatttt aatgttcggg atgcaccttg ccggcgcgct
    24361 gggtcgcgcg gtgcttccgg atctgacggt gccggatctg gtgatcccaa cgctaatggt
    24421 gaaagttttg ccgccgtttg ccgccgggat cttccttgct gcgccaatgg cggcgatcat
    24481 gtcaacaatt aacgcccaac tgctgcaaag ttccgcgacg atcattaaag atctctatct
    24541 caacctgcgt cccgatcaga tgcaaaatga gatccggctg aagcgtatgt cggcagcgat
    24601 tacattactg ttaggcgcgc tgttgctgct ggccgcgtgg aaaccgccag agatgatcat
    24661 ttggctcaac ctgctggcgt ttggcggcct ggaagcggtg ttcttatggc cgctggtact
    24721 gggcctttac tgggagcggg caaacgcggc aggcgcgtta agcgccatga tcgtgggcgg
    24781 cgtgctatat gccctgcttg ccacatttaa tattcagtac ctgggctttc atccgattgt
    24841 gcccgcgtta ctgttaagtt tattggcttt tctgatcgga aaccgattcg gctcttccgc
    24901 ttcgcaagcc accgtattgt ctactgataa ataaagagtt ttgccatgcc atggatccaa
    24961 ttgaaactga ataccaccgg cgcgaatgct gaagagctaa gtgatgcgct gatggaagcg
    25021 ggcgccgttt ccattacctt tcaggataca cacgatacgc cggtttttga gccgttgccg
    25081 ggcgaaaccc gtctgtgggg cgataccgat gtgatcggtc tgttcgacgc cgaaacagac
    25141 atgaaagacg ttgtcgcgat tctggagcaa catccactgc tgggtgccgg atttgcccat
    25201 aaaatcgaac aactggaaga taaagactgg gaacgcgaat ggatggataa tttccatccg
    25261 atgcgttttg gcgagcgtct gtggatttgt cccagctggc gtgacattcc ggacgagaat
    25321 gccgtcaacg tgatgctcga cccgggactg gcgttcggta cgggtacgca ccccaccacc
    25381 tctttatgtc tgcaatggct ggacgggctc gatctcaacg gcaaaaccgt gatcgacttt
    25441 ggctgcggtt caggcattct ggcgattgcc gcgctgaagc tgggagcggc aaaggcgatt
    25501 ggtattgata tcgatccgca agctattcag gccagtcgcg ataatgccga acgtaacggc
    25561 gtgtctgacc ggctggagct gtacctgccg aaagaccagc cagaagccat gaaagccgac
    25621 gtggtcgtcg ctaacatcct ggcaggccca ttacgcgaac tggccccgtt aatcagcgta
    25681 ctgcccgttg agggcggtct gctggggctt tcaggtattc tcgccagcca ggcggaaagc
    25741 gtctgtgatg cttacgccga gcttttcact ctcgacccgg tcgtcgaaaa agaagagtgg
    25801 tgccgcatta ctggccgtaa gaaataattc ttgtcagcgt ggtcgcccgg ccacgctttt
    25861 ctccacacaa ctgccttaac gcctttcagg caccgagaca tcattaaatt catcaaatga
    25921 atgcctgaaa taacttcttt gtcactatcc gtctggataa acagctgcta ccagcggaca
    25981 aacgtactgg cgcttcaacg gcccgcagcc atcgccctcg tacttagtaa atgctgtccg
    26041 ggttgttctg cagcatccgc taacgctctt tttagcgcag ctggaaaaat ttatgcgtgc
    26101 cgttcatgaa cacaaaagcg catctgtgca ccccttccga ctggcaatgg agaaaaatca
    26161 cgcgcagcgg gaagtgatct tgtcctgaaa cgagacggcg atcccattca tttggggtaa
    26221 ttagcttata aaaaaagcag attattccgc ttatcttgtt tctggtcgaa gaaatagaga
    26281 gaagttacgg gaatttgtaa gcgcgtacaa aaccgccgac aataaataac cctatgattt
    26341 tactgaatta taaatttatt ttgctg
//
LOCUS       DAJVKX010000055        26158 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000055 DAJVKX010000000
VERSION     DAJVKX010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26158
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.055"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(82..783)
                     /gene="fre"
                     /locus_tag="OPY25_002375"
     CDS             complement(82..783)
                     /gene="fre"
                     /locus_tag="OPY25_002375"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HCS0927977.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRLVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASELNLYAMAVMDRILKDREIVVDIPHGDAWLRDDE
                     ERPLILIAGGTGFSYARSILLTALARNPARDVTIYWGGREEKHLYDLSELEALSVNHP
                     NLRIEPVVEQPEEGWRGRTGTVLTAVLQDYGTLAGHDIYIAGRFEMAKIARDLFCHER
                     NAREDRLFGDAFAFI"
     gene            complement(869..2347)
                     /gene="ubiD"
                     /locus_tag="OPY25_002376"
     CDS             complement(869..2347)
                     /gene="ubiD"
                     /locus_tag="OPY25_002376"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HCS0927978.1"
                     /translation="MDAMKYHDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYAMPVLCNLFGTPKRVAMGMGQDDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIASGDDVDLTRLPVMTCWPDDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDFQEWLAARPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCLSNDLEVPASAEIILEGY
                     IEPGEMAPEGPYGDHTGYYNEVDNFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTMKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIVKDPEVTARIDAIWDELAIFK"
     gene            2533..3021
                     /gene="rfaH"
                     /locus_tag="OPY25_002377"
     CDS             2533..3021
                     /gene="rfaH"
                     /locus_tag="OPY25_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HCS0927979.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVSCLTPMITLEKMVRGKRT
                     FVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGAHPAIVPSSVIHQLSIYKPE
                     GVVDPETPYPGDSVIITEGAFEGLKAIFTEPDGETRSMLLLNLLNKEVKQSVKNTGFR
                     KI"
     gene            complement(3029..3811)
                     /gene="tatD"
                     /locus_tag="OPY25_002378"
     CDS             complement(3029..3811)
                     /gene="tatD"
                     /locus_tag="OPY25_002378"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462861.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HCS0927980.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQ
                     ALKLARRYPHCWSTAGVHPHDSSQWSSASEDAIIALANQPEVVAIGECGLDFNRNFST
                     PQEQERAFQAQLQIAAELQMPIFMHCRDAHERFLALLDPWLDSLPSAILHCFTGSRQQ
                     MQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTS
                     RRNEPAYLPHILERIALWRGEDPQWLAAMTDANARTLFEVVF"
     gene            complement(3853..4632)
                     /gene="tatC"
                     /locus_tag="OPY25_002379"
     CDS             complement(3853..4632)
                     /gene="tatC"
                     /locus_tag="OPY25_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HCS0927981.1"
                     /translation="MAVEDTQPLITHLIELRKRLLNCIVAVLLIFLALIYFANDIYHL
                     VAAPLIKQMPQGATMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLTHTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVAFEVPVAIVLLCWMGITTPEDLRKKRPYILVGAFIVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFCSRFYVGKRRTRDEDNEAETEKAEHTED"
     gene            complement(4635..5183)
                     /gene="tatB"
                     /locus_tag="OPY25_002380"
     CDS             complement(4635..5183)
                     /gene="tatB"
                     /locus_tag="OPY25_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HCS0927982.1"
                     /translation="MFDIGFSELLLVFVIGLIVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLENLTPELKASMDELRQAAESMKRTYSANDPE
                     QASDEAHTIHNPVVKGNETQHEGVTPAAAETQASAPEQKPEPVKANVPESTETASVAA
                     IDAEKKSAAPVVESSPSSSDKP"
     gene            complement(5187..5441)
                     /gene="tatA"
                     /locus_tag="OPY25_002381"
     CDS             complement(5187..5441)
                     /gene="tatA"
                     /locus_tag="OPY25_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HCS0927983.1"
                     /translation="MGGISIWQLLIVAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDDAKQDKTSQDADFTAKSIADKQGEAKKEDAKSQDKEQV"
     gene            complement(5647..7287)
                     /gene="ubiB"
                     /locus_tag="OPY25_002382"
     CDS             complement(5647..7287)
                     /gene="ubiB"
                     /locus_tag="OPY25_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HCS0927984.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPRMRLTLPLRLWRYSLFWM
                     PNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPQIADQLALLQDKVAPFDG
                     RLAKAQIEEAMGGLPVEAWFDDFDIQPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIQADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFENSPMLYIPEVYSDYCSQNMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVKVFF
                     TQVFRDSFFHADMHPGNIFVSHEHPENPQYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALTRAL
                     KEKAPFWVEKMPEIPELVYDSLRQGKYLQHSVDKIARELQVNHVRQSQSRYLLGIGAT
                     LLLSGSFLLVNRPEWGLMPGWLMVGGVVVWLVGWRKTR"
     gene            complement(7284..7889)
                     /gene="ubiJ"
                     /locus_tag="OPY25_002383"
     CDS             complement(7284..7889)
                     /gene="ubiJ"
                     /locus_tag="OPY25_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HCS0927985.1"
                     /translation="MPFKPLVTAGIEGLLNTFLYRSPALKSARTRLQGKVLCVKLKGF
                     STPLVLVFSERQVDVLGAWEGEADCTVITQASVLPKLRDRQQLAALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAESIGKVVRGGAKFLRHGFQRQQRYAAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDSLTTRLEKLGAK"
     gene            complement(7899..8654)
                     /gene="ubiE"
                     /locus_tag="OPY25_002384"
     CDS             complement(7899..8654)
                     /gene="ubiE"
                     /locus_tag="OPY25_002384"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HCS0927986.1"
                     /translation="MVEDSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRMVGETGKVILADINDSMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTEKEKALRSMFRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPRIGSMVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            complement(8750..10180)
                     /gene="rmuC"
                     /locus_tag="OPY25_002385"
     CDS             complement(8750..10180)
                     /gene="rmuC"
                     /locus_tag="OPY25_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HCS0927987.1"
                     /translation="MDITLMISAVVALAAGAVIGWLATKAHADQIRADLIEERRELDI
                     ELSAARQQLAQEAHWRSECELLNNELRSLHSINTSLEADLREVTTRLEATQQHAEDKI
                     RQMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLTPLREQLDGFRRQVQES
                     FGKEAQERHTLAHEIRNLQQLNAQMAQEAINLTRALKGDNKAQGNWGEVVLARVLEAS
                     GLREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYT
                     REAALQEHIASVRNHIRLLGRKDYQQLPGLRSLDYVLMFIPVEPAFLLALDKQPELIT
                     EALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQHIADRASKLYDKMRLFVDDMSA
                     IGQSLDKAQDNYRQAMKKLASGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVTQDEE
                     YRLRSIPEGRQDEHYPNDERVKQQLS"
     gene            complement(10320..11081)
                     /gene="udp"
                     /locus_tag="OPY25_002386"
     CDS             complement(10320..11081)
                     /gene="udp"
                     /locus_tag="OPY25_002386"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HCS0927988.1"
                     /translation="MSKSDVFHLGLTKNDLQGAQLAIVPGDPERVEKIAALMDKPVKL
                     ASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPMEFPAVADFACTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRRFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL"
     gene            11340..12152
                     /locus_tag="OPY25_002387"
     CDS             11340..12152
                     /locus_tag="OPY25_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HCS0927989.1"
                     /translation="MTTTHPSGFAPAASPLAPTMIHTPDGAISAGITSIPSQGDDMPA
                     YYARPKASDGALPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDAHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLVGDTSLNSPKHPVDIATDLNAPVLGLYGGQDTSIPQESVETMRQA
                     LRAANAKAEIVVYPDAGHAFNADYRPGYHEASAKDGWQRMLEWFAQYGGKKG"
     gene            complement(12228..13526)
                     /locus_tag="OPY25_002388"
     CDS             complement(12228..13526)
                     /locus_tag="OPY25_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001785009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HCS0927990.1"
                     /translation="MAVAGCHVMAKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSD
                     ETLEQFIRQHIAAQSGDRIDFAWQCGEPTMMGLPFFRRVVALCEKYGDGRKITHALQT
                     NGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRLNRAGKGTHEQVVAAMARLKAHH
                     VDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESA
                     AKLAPWTVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQQPVLCVHSETC
                     GHAFALESNGDLYNCDHFVYPEHLLGNIHQHSIKTLNNSERAIAFGEAKRETLTADCR
                     RCDYRFACHGGCPKHRFAVSPSGHPAHNYLCTGYKHFFQHVTPYMNVWRELLAQGYPM
                     ASIMRWLAQDARKDTGAVSRNHLCPCGSGKKYKNAVVKHS"
     gene            complement(13909..16173)
                     /gene="metE"
                     /locus_tag="OPY25_002389"
     CDS             complement(13909..16173)
                     /gene="metE"
                     /locus_tag="OPY25_002389"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCS0927991.1"
                     /translation="MTILTHTLGFPRVGLRRELKKAQESYWAGNTTREALLAVGRELR
                     ARHWEQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNNDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYIVPEFSKGQQFRLTWTQLLEEVDEALALGHKIKPV
                     LLGPVTYLWLGKVKGEPFDRLTLLKDILPVYQHVLAELAKRGVEWVQIDEPALVLELP
                     QAWLDAFKPAYDALAGQVKLLLTTYFEGVTPNLDTIIVLPVQGLHVDLIHGKDDVVEL
                     HQRLPVDWLLSAGLINGRNVWRADLTEKYAQINAIVGKRALWVASSCSLLHSPIDLSV
                     ETRLDTEVKSWFAFALQKCGELALLRDALNSGETAALEEWSVPIQARRHSHRVHNAAV
                     EKRLAAITAQDSQRENPYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKKG
                     NLDANNYRTGIAEHIKQAIIEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPVVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVTRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLEWGVEA
                     FRINAAVAKDETQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEAFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAQRIPAQRLWVNPDCGLKTRGWPETRAAL
                     ANMVKAAHNLRQAK"
     gene            16422..17375
                     /gene="metR"
                     /locus_tag="OPY25_002390"
     CDS             16422..17375
                     /gene="metR"
                     /locus_tag="OPY25_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HCS0927992.1"
                     /translation="MIEIKHLKTLQALRNSGSLAAAAAVLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEVLLQLANQVLPQISRALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFRASWPQVEMDFTSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     FEVRLVLAPDHPLASKTQITPEDLASETLLIYPVQRSRLDVWRHFLQPAGISPLLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESVERQGLVVTKTLGDGLWSRLYAAVRDGDQRQA
                     VTEAFIRSTRDHACDHLPFVRSAERPIFDAPTAKPGSQPRL"
     gene            complement(17263..18162)
                     /locus_tag="OPY25_002391"
     CDS             complement(17263..18162)
                     /locus_tag="OPY25_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0927993.1"
                     /translation="MALLIITTILWAFSFSLFGEYLAGHVDSYFAVLIRVGLAALVFL
                     PFLRTRGHNLKTISLYMLVGAMQLGIMYMLSFHAYLYLTVSELLLFTVLTPLYITLIY
                     DVMSQRRLRWGYAFSALLAVIGAGIIRYDRVTDHFWVGLLLVQLSNISFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAAVAWSLLGNAQKLPETTLQWSILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPSFITGAAVILASLWVH
                     RKWVAPRSAQTADDRRRDPASSE"
     gene            complement(18243..19043)
                     /gene="yigL"
                     /locus_tag="OPY25_002392"
     CDS             complement(18243..19043)
                     /gene="yigL"
                     /locus_tag="OPY25_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HCS0927994.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGIHFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDTDGNLVFTHNLDSDIASDLFGVVNANPDIV
                     TNVYRDDEWFMNRHRPDEMRFFKEAVFNYSLFEPALLEPEGVSKVFFTSDTHEKLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAQAMGYSLKECIAFGDGMND
                     AEMLTMAGKGCIMGNAHQRLKDLYPELEVIGINADNAVPHYLRDLFLR"
     gene            complement(19059..20075)
                     /gene="pldB"
                     /locus_tag="OPY25_002393"
     CDS             complement(19059..20075)
                     /gene="pldB"
                     /locus_tag="OPY25_002393"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HCS0927995.1"
                     /translation="MFQQQNDWETRENAFAAFAMGPLTDFWRQREEAEFIGVDNIPVR
                     FVRFRNDSNDRTIVICPGRIESYVKYAELAYDLFHLGFDIFIIDHRGQGRSGRMLSDP
                     HRGHVDHFNDYVEDLAAFWQQEIEPGSWRKRYILAHSMGGAIATLFLQRHRVRCDAIA
                     LTAPMFGIVIRLPSFMVRHILDWAEGHQRIREDYAIGTGQWRALPFGMNALTHSRQRY
                     QRNLRFYADEPQLRVGGPTWHWVREGILAGEQVLAGASDDTTPTLLIQAEEERVVDNR
                     THDRFCEIRAAAGYPCEGGKPLVIKGAYHEILFEKDAMRSVALNAIVEFFNKPNLSSG
                     NRFA"
     gene            20186..20806
                     /gene="rhtB"
                     /locus_tag="OPY25_002394"
     CDS             20186..20806
                     /gene="rhtB"
                     /locus_tag="OPY25_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HCS0927996.1"
                     /translation="MTFEWWFAYLLTSTLLSLSPGSGAINTMTTSINHGYRGAAASIA
                     GLQTGLGIHIVLVGVGLGTLFSRSLIAFEILKWAGAAYLIWLGIQQWRAAGAIDLHTL
                     AQTQSRGRLFKRAIFVNLTNPKSIVFLAALFPQFIMPQQPQLAQYLILGVTTIVVDMI
                     VMTGYATLAQRIAAWIKGPKQMKALNKAFGSLFMLVGALLASARHA"
     gene            complement(20846..21466)
                     /gene="rhtC"
                     /locus_tag="OPY25_002395"
     CDS             complement(20846..21466)
                     /gene="rhtC"
                     /locus_tag="OPY25_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HCS0927997.1"
                     /translation="MLMLFFTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGVALLGLHLIIEKMAWLHTIIMVGGGLYLCWMGYQMLRGALKKQDAAAS
                     SPHIELAQSGRSFLKGLLTNLSNPKAIIYFGSVFSLFVGDNVGAAARWGIFALITLET
                     LAWFTVVASLFALPKMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(21530..23359)
                     /gene="recQ"
                     /locus_tag="OPY25_002396"
     CDS             complement(21530..23359)
                     /gene="recQ"
                     /locus_tag="OPY25_002396"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCS0927998.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEAIIDTALSGRDCL
                     VVMPTGGGKSLCYQIPALLLDGLTVVVSPLISLMKDQVDQLLANGVAAACLNSTQSRE
                     QQLEVMAGCRTGQIRLLYIAPERLMLDNFLDHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPALPFMALTATADDTTRQDIIRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLENAIRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPAGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGLNDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDF
                     GHDKLKVYGMGREKSHEHWVSVIRQLIHLGLVMQNIAQHSALQLTDAARPVLRGDVPL
                     KLAVPRIVALKPRVMQKSFGGNYDRKLFAKLRKLRKAIADEENIPPYVVFNDATLIEM
                     AEQMPVSASEMLSVNGVGMRKLERFGKEFMALIRAHVDGDDEE"
     gene            complement(23443..24312)
                     /gene="pldA"
                     /locus_tag="OPY25_002397"
     CDS             complement(23443..24312)
                     /gene="pldA"
                     /locus_tag="OPY25_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HCS0927999.1"
                     /translation="MRAILRGLLPATLLPLAAYAQEATIKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYLIYTNTSDLNKEAISTYNWSENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSKESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVIGSTDDNPDITKYMGYYQLK
                     IGYHLGEAVLSAKGQYNWNTGYGGAEVGLSYPVTKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDIF"
     gene            24477..24944
                     /locus_tag="OPY25_002398"
     CDS             24477..24944
                     /locus_tag="OPY25_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HCS0928000.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGLELERYEKAFAQLAF
                     NNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGNRFTATSSLLRAGNKVAVARVELHNEDQLYIASATATYMVG"
     gene            24988..25872
                     /gene="rarD"
                     /locus_tag="OPY25_002399"
     CDS             24988..25872
                     /gene="rarD"
                     /locus_tag="OPY25_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HCS0928001.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVALLSVSRQWRQVKRLLKTPKKIFLLALSAVLVGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNILLGMIFLGERFRRMQWLAVILAVCGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLVETLWLLPVAAIYLFSIADSATSHMGQNALSLNLLLMA
                     AGVVTTIPLLCFTGAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEVPGADKMVTFAFI
                     WVALAIFVMDAIYTQRKK"
     gene            25907..>26158
                     /locus_tag="OPY25_002400"
     CDS             25907..>26158
                     /locus_tag="OPY25_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928002.1"
                     /translation="MPPLVRGVAYCHANDVTQHMDVKLMLSVFIPSSERCVSRCRYLL
                     SFALINIIFSILVGVLLYLSFVILAILFTILLHYLVINLN"
BASE COUNT         6255 a         7259 c         6586 g         6058 t
ORIGIN      
        1 tagttgacga ttaattaata tttaagagga cttttaggta ggctaacgta aaaagggacg
       61 ctactgcgtc ccataaaata gttaaataaa tgcgaacgca tcgccaaaca gacgatcttc
      121 ccgcgcatta cgctcatgac agaacagatc gcgggcgatt ttcgccatct caaaacgtcc
      181 ggcaatataa atatcgtgcc ccgccagcgt accataatcc tgcaataccg ccgtaagtac
      241 cgttcctgta cgtccacgcc agccttcttc cggctgctcg acaacaggtt caatacgcaa
      301 attaggatgg ttaacagaga gtgcttccag ctcagagaga tcatagaggt gcttttcttc
      361 gcgaccgccc cagtaaatgg taacatcgcg ggccgggttg cgcgctaacg ccgtcaacag
      421 gatggagcgt gcataagaaa agcccgtacc gcccgcgatc agaatcaacg gacgctcttc
      481 atcgtcacgt agccaggcgt cgccatgcgg aatatcgacg acgatttccc ggtctttcag
      541 aattcgatcc atgaccgcca tcgcatacag attgagctcg gaagcgccaa tgtgtaattc
      601 aataaaccct ttctcgtccg gcgttgaggc catcgaaaac gggcgtttgt cacgctcgtc
      661 cattacgacc atcaaatact gaccagcgcg gaatgaaaac gccgcgtccg gcactaaacg
      721 aacccgatat acggtatcgg tgatagcttc taccgaggtc actttacagc ttaaggttgt
      781 catgcgctcc ctctgtcggg tgtcgggtca ataccgacat ttttcaagcc gagtcgccgc
      841 agcctgaaat gtcgatgtcc gctttcagtt atttaaagat agccagctca tcccaaatcg
      901 catcaatacg cgcggtaact tcaggatctt taacaatagg acgaccccac tcgcgttggg
      961 tttcgcccgg ccatttgttt gtggcatcca gccccatttt tgaacccagc ccggagaccg
     1021 gcgaggcaaa atccaggtag tcaatcggcg tattttcaac cagcaccgta tcccgcgcag
     1081 ggtccatacg ggtggtaatc gcccagatca catcattcca gtcgcgtgcg ttaacgtcat
     1141 catcgcaaac gataacaaat ttcgtataca taaactggcg caaaaacgac cagacaccca
     1201 tcatgacgcg tttcgcatga ccagcgtact gctttttcat cgtcactacc gccaggcggt
     1261 aagaacaccc ttccggcggc agataaaagt cgacgatttc cggaaactgt ttttgcagaa
     1321 taggcacgaa gacttcattg agcgccaccc ctaataccgc aggctcatcg ggcggacgcc
     1381 cggtataggt ggagtgatag atggcatcct cacgctgcgt aatatgcgtg acggtaaaga
     1441 ccggaaagtt atccacttca ttataatagc ccgtatgatc gccatacggt ccttccggcg
     1501 ccatctctcc cggctcaatg taaccttcaa ggataatctc ggcgctggca ggcacttcca
     1561 gatcgttaga aaggcattta accacttcag ttttcgtgcc gcgcagcagg cccgcaaagg
     1621 catactccga cagagtatcg ggaacaggag tcacggcgcc aagtatcgtc gccggatcgg
     1681 cgcccaatgc gacggagacc gggaaacgtt cacccggacg cgcggctaac cactcctgaa
     1741 aatccaacgc gccgccgcgg tgagacagcc agcgcataat cagcttattt ttacctatca
     1801 actgctgacg ataaatgccc aggttttgcc gttctttgtg cgggccacgc gttaccgtca
     1861 gtccccaggt aatcagcggc gcggcgtcgt ccggccaaca ggtcatgaca ggaagacgcg
     1921 ttaaatcgac atcatcgcca gacgcgattt tctgctggca aggcgcgccg cgtaaccgtt
     1981 tcgtcggcat attcagcact tgcttaaact gcggcagctt gtcaaacaga tcgcgaaagc
     2041 ctttcggcgg ctcaggttct ttcagaaacg ctaataattt acccacttcc cgtaaggcgg
     2101 aaacatcatc ctgccccatg cccatcgcca cgcgttttgg cgtgccaaaa aggttgcaca
     2161 gcaccggcat ggcgtaacct ttaggatttt caaacagcaa cgccggtcca ccggcacgca
     2221 gcgtgcggtc agcgatttcc gtgatttcca gatgaggatc cacaggtagc gtgatgcgtt
     2281 ttagttcccc ctgctgctca agtagcgtca ggaagtcgcg taaatcgtga tatttcatgg
     2341 cgtccattgt agcctcttgg taagcgcatc attatacggc gttcatcatc gggatgctgt
     2401 atttttgtta aattagcgtg aactctggca accaacgcta atccagatac ggcttaaagg
     2461 atgaagtgta taattaactt cgcgcatggc ttttgctatg cttgcgcccc gaacaagcgg
     2521 ataagagtca ttatgcaatc ctggtattta ctgtactgca aacgcgggca acttcagcgt
     2581 gctcaggaac acctcgaaag acaagcggta agttgcctga caccgatgat caccctggaa
     2641 aaaatggtac gcggaaaacg taccttcgtc agcgaaccgc tctttcctaa ttatctgttc
     2701 gttgaatttg atccggaagt gatacatacc actacaatca acgccacgcg cggcgtcagc
     2761 cattttgtgc gctttggcgc gcatcctgcg atcgtgcctt ccagcgttat tcatcagctt
     2821 tctatctaca agcccgaagg cgttgtcgat cctgaaaccc cctatcccgg cgatagcgtc
     2881 atcatcacgg aaggcgcatt tgaagggctg aaagcgattt ttaccgaacc ggatggcgaa
     2941 acgcgttcga tgttactgct taatttactc aataaagaag tgaagcagag cgtaaaaaac
     3001 accggttttc gcaagattta gcgatcgttc agaatacgac ctcaaataag gttctggcat
     3061 tggcatctgt catcgccgct aaccattgcg gatcttcacc acgccatagc gctatgcgct
     3121 ccaggatgtg aggcagatat gcgggctcgt tgcgtcgtga cgttggtttc ggcgtaagat
     3181 cgcggggcaa cagatacggc gcgtcggttt ctatcagtag cttttccgct ggaataaacg
     3241 gtaagagttc acgtagctca agcccgcgtc gttcgtcgca aacccacccg gtaataccga
     3301 tatagagccc tctgtccaca caggcctgca tttgctggcg tgaaccggta aagcagtgca
     3361 gtattgcact aggaagacta tccagccagg gatcaagcaa tgccagaaat cgctcatgcg
     3421 cgtcccggca gtgcataaag attggcatct gcaattcggc ggcaatttgt agctgcgcct
     3481 gaaaggcacg ctcctgctcc tgcggcgtgg aaaaattgcg attgaaatcc agcccgcact
     3541 caccgatagc gacgacttcc ggctggttcg ccagcgcaat aatggcgtct tcagacgcag
     3601 atgaccactg actgctgtca tggggatgga cgccagccgt cgaccaacaa tgggggtagc
     3661 gccgcgccag ttttaacgcc tgctgacttt catggatgtt cgttccggtc agtagcatac
     3721 cttttactcc tgccgcaaac gcacgggcga ccacatcatc acgatctttt gcaaactggc
     3781 tactggttaa attaacgcca atatcaaaca tgcttgcccc catatgacaa ccgccctggc
     3841 gggcggttgt gtttagtctt cagtgtgctc ggccttttcg gtctcggcct cgttatcttc
     3901 gtcgcgcgtc cgtcgcttac cgacataaaa gcgtgagcag aaaacgccaa tttcaaacag
     3961 gcagtacatc ggtatcgcca gcaacgtttg cgagaagaca tctggcggcg taagcagcat
     4021 ccccacaatg aatgccccga ccaggatata aggccgtttt ttacgcaaat cttctggcgt
     4081 ggtgatgccc atccagcaca gcaacacaat cgccaccggc acctcaaagg ctacgccaaa
     4141 ggccataaaa agcgccatga caaagctcag atagctggcg atatctgtcg aaacctgtac
     4201 cccttccggc gccgtatgcg tcaggaaacc aaaggccaaa gggaatacga caaaataggc
     4261 gaaggccata ccaatgtaaa aaagcagcga actggatacc agcagcggta cgaccagacg
     4321 acgctcgtgt ttatacagcg ccggggcgat aaaggcccaa acctggtaca aaatgacagg
     4381 cgcggataag atcaaagaca ccatgaaggt gagtttgata ggcgtaaaaa acggcgacgc
     4441 cacatccgtc gcaatcattg tcgccccttg cggcatctgt tttatcagcg gtgcggcgac
     4501 taaatgataa atatcattgg cgaaataaat taacgccaga aaaatcagaa gtactgcgac
     4561 gatgcagttt agcaggcgct tacgcaactc gatcagatgc gtgataagcg gttgagtatc
     4621 ttctacagcc atgtttacgg tttatcactc gacgaggggg aagattcgac aacaggcgca
     4681 gcggatttct tctcggcgtc tatcgcggct acggaagcgg tttccgtcga ctcaggcacg
     4741 ttagctttaa cgggctccgg cttttgttcc ggcgcgctcg cctgtgtttc agcggcggca
     4801 ggggtgacgc cctcatgctg cgtttcgttc ccttttacca ccggattatg gatggtatgc
     4861 gcttcatcgc tcgcttgttc gggatcgtta gcgctgtagg tgcgtttcat cgactccgcc
     4921 gcctgacgca gttcatccat agatgctttc agttcgggag tcagattttc caggctcgcc
     4981 ttttcgactt ttttcagact gtcctggaac tcctgaagtt tcagttcctg agtcagttca
     5041 ttctgaaccg ttgtcgcaag ggagcgcaac gcgcgaatcc agcccgctac cgtttttacc
     5101 gctactggca atcgttgcgg ccccaacaca atgaggccga taacgaacac taacagcagt
     5161 tcgctaaaac cgatatcaaa cacggattat acctgctctt tatcttggct tttagcgtct
     5221 tcctttttcg cttcgccttg cttatccgcg atagatttag cggtaaaatc agcgtcctga
     5281 ctggttttat cctgtttggc atcatcatcg ctcatggcct ttttaaagcc tttgatagac
     5341 gcgccaagat cggaaccgat ggaaccgagt tttttggtgc cgaacagcag tacgacgata
     5401 acggcaacaa tcaacaactg ccaaatactg ataccaccca tacatgttcc tctgtgatag
     5461 atgatgaatt attagggccg cattatacac attatccttc gcgctgcctc tttgttagcc
     5521 gctttcgccc gtcctattca catactttta catacgaccg ggacgacatt gacttgcggc
     5581 ctgagtattg cctcgagtga taatatgtac ctgcgtgaca caaccggcgt tgagcgataa
     5641 aaaatctcaa cgagttttac gccagccaac cagccagacc actacgccgc cgaccatgag
     5701 ccagccaggc atcaatcccc attcagggcg gttgacgagt aagaatgacc cgctcagtaa
     5761 cagcgttgcg ccaattccca ataaataacg agactgactt tggcgcacat ggtttacctg
     5821 taactcgcgc gcaatcttat caacactgtg ctgtaaatat ttgccctggc gcaaactgtc
     5881 gtacaccagt tcaggtattt ctggcatttt ttcgacccag aacggcgctt tttctttaag
     5941 agcccgcgtg agagccggaa tacccacctg atctttgatc caggactcaa gaaacggctt
     6001 cgccgttttc cacaaatcaa gctgaggata aagttgccgc ccaacccctt caacatacaa
     6061 taatgttttc tgcaacaaca ccagttgcgg ctggacttcc atgttaaatc gacgcgctgt
     6121 attgaaaagg tttaacaaca catgaccaaa cgagatttcc gcgagcggct tttcaaaaat
     6181 aggttcacag acggtgcgga tggcaaactc aaaatcttca acgttggtat ctggcggaac
     6241 ccaacctgaa tcgacatgca gctccgccac ctttcggtaa tcgcgattaa aaaacgcgat
     6301 aaagttttca gccagataac gcttatcttc tttgtttagc gacccgacga taccgcagtc
     6361 aatgccgata tattgcggat tttcagggtg ttcatgactg acaaaaatat ttcccggatg
     6421 catgtccgca tggaaaaagc tgtcgcggaa aacctgggtg aagaaaactt taactccgcg
     6481 ttccgccagc agtttcatgt tggtgccgtt cttttccagc gccgccacat ccgaaaccgg
     6541 aatgccatat atccgctcca tcaccatcat gttctggcta cagtaatcgg agtacacctc
     6601 cgggatatac agcatgggac tattttcaaa attgcgacgt aactgaatcg cgttggccga
     6661 ttcccgcagc agattcagct catcgatcag cgttttctca tactcacgca ccacttccgt
     6721 cgggcgcaga cgacgcccat ccggcaacag gcgtggtacc cagcgagcaa ggcgataaat
     6781 cagtttcagg tctgcctgaa ttaccggcaa aatatccggg cgaatgacct taataaccac
     6841 ttctttaccg tttgatttca atcgcgcggt atgtacctgg gcgattgacg ccgacgctaa
     6901 aggctggata tcaaagtcgt caaaccaggc ttcgacaggt agccccccca tcgcctcttc
     6961 aatctgggct ttcgccagcc gaccatcgaa tggcgcgact ttatcctgga gcaaagcgag
     7021 ctgatcggcg atttgcggcg ggaacaggtc acggcgcgtg gagagcatct gaccaaattt
     7081 gatccagacc ggtcccagct cttgcaacgc cagtcttaat cgttcaccca gcaatttatc
     7141 tttatgccgg tttggcatcc agaacagcga atagcgccat aatcggagtg gcagtgtaag
     7201 acgcattcgg gggatgagtt catcaaggcc gtagcttaga aacgtgcgga tgatgaaata
     7261 taggcgccgt acttcacctg gcgtcatttg gcccccagtt tttccagccg tgtggtcaga
     7321 gaatctacgg cgcgctcaac agccgcggtt tcttcggcaa accatgcgac ttccagcggg
     7381 ccaggcgcca tacgccactc ttcagtgatc gcttcagcgg cataacgctg ctggcgttga
     7441 aacccgtggc gcaggaattt agccccgcca cgcacgacct taccgatact ttccgccgca
     7501 atatcacccg tgtatggcgc caacagctcc gcaggatcga attcggcgag atcggcgagc
     7561 gccacaaaat tttgcacgac ctgaatatcg ccctgcactt ccagttcgcc gctgcgaata
     7621 agcgcggcca actgctgacg atcgcgtagt tttggcaaaa cgctagcttg agtgattacc
     7681 gtacagtccg cttcgccttc ccatgccccc agcacatcaa cctggcgttc actgaatacc
     7741 aggactaatg gcgtcgaaaa tccctttagt ttcacacaca gtacttttcc ctgtaagcgc
     7801 gttctggctg atttcagcgc tggcgaacga tacagaaacg tattgaggag accttcaatt
     7861 cctgcggtca ctaagggttt aaaaggcatt ccaccctcct agaatttata accacggtgc
     7921 aatgccacaa cgcccgccgt cagattgtaa taatccacgc tctcaaatcc ggcgtcctgc
     7981 atcatggctt ttaaggtatc ctgatcggga tgcatacgga tggattccgc gagataccga
     8041 tagctatccg catcgttcgc gaccatcgag ccaatacgcg gtaaaatatg gaaagaatag
     8101 gcgtcatacg ctttactcag cggctcaatg ataggcttgg aaaattcaag caccagtaaa
     8161 cgtccgccgg gtttcaacac acggaacatt gaccgcagcg ctttttcttt ttccgttaca
     8221 ttgcgcaaac caaacgaaat ggtaatgcaa tcaaacgtat tatcagggaa aggcagagct
     8281 tcggcattcg cctgcacata ctctacgttg ccgatcacgc cgatattacg cagcttctca
     8341 cgccccattt tgagcataga atcattaata tccgccagga taactttgcc agtttccccg
     8401 accatacgtg aaaatttcgc ggtaagatcg cccgtcccgc ccgctaaatc gagaacggtt
     8461 tgtccacgac gcacgccact gcaatcaatg gtgaagcgct tccacaaacg atgaatgcca
     8521 aatgacatta aatcattcat cacatcgtac tttgacgcca cagaatgaaa aacgtgggcc
     8581 accatgtcag ctttctgctc tttagcgacg gtctgaaagc caaagtgcgt cgtttcttgt
     8641 gaatcttcca ccatctcagt gcctgcttat cgataaaaat gttcaagaag tgtaacagat
     8701 tgggccaatt tgccctactc tgcgccagga ctaaactact ccgtatgggt taacttaact
     8761 gctgcttcac ccgttcatca ttgggataat gttcatcctg ccgcccttca gggatcgatc
     8821 gtaaacgata ttcttcatct tgcgtaacgg cctgttccgc taaatccgga ttaatctcgc
     8881 gtttgatttc cacgcctagc ccccggaagg cctccgcctg cgccaaaacg ttgccacgcc
     8941 ccgacgcaag ttttttcatc gcctggcggt agttatcctg cgctttatcc agactctgac
     9001 cgatcgctga catatcatca acgaacaacc gcattttatc gtagagctta ctggctctgt
     9061 ctgcgatgtg ctgcgcattg cggctctggt gttcatagcg ccacaggttg gcgattgtcc
     9121 gtaacgccac cagcagcgtc gtggggctta ccagcataat gttatttttc agcgcctcgg
     9181 ttatcagttc gggctgttta tctaacgcca gcaggaaagc gggttctacg gggataaaca
     9241 tcagaacata gtccagcgag cggaggccgg gaagctgctg gtagtcttta cgccccagta
     9301 agcgaatatg attgcgcacc gaggcgatgt gctcttgtaa agcggcctcg cgcgtatagt
     9361 catcttcagc gttaaagtaa cgctcgtagg cgactaacgt cattttagcg tcgatgacca
     9421 catctttgcc ctgcggcaag cggacgatga catccggctg catccgcgag cgcgcatcgt
     9481 tctcaatact gacctgggtt tcgtattcgt agccttcacg cagtccggat gcctccagca
     9541 cccgcgccag cacaacttcg ccccagtttc cttgtgcctt attgtcccct ttcagggcgc
     9601 gcgtcaggtt gatcgcttcc tgcgccattt gcgcgttaag ctgctgcaaa ttacgaattt
     9661 cgtgcgccag cgtatgccgc tcctgcgctt ctttgccaaa actctcctga acctggcggc
     9721 gaaaaccgtc cagttgctca cgcagcggcg tcagcaggct attcaggctt tgtcggtttt
     9781 gttcgtctac gcgacgatta ctgtgttcaa agatacggtt cgccagattt tcaaactgct
     9841 cgcttaaacg ctgttcgctg ttgatcatct gacggatttt gtcttccgcg tgttgttgag
     9901 tcgcttccag acgagtcgtg acttcacgca gatcggcttc cagagaggta ttaatactgt
     9961 gcaggctacg cagttcgtta ttaagtaact cgcattcact gcgccagtgc gcttcttgcg
    10021 ctaattgctg ccgggccgcg ctaagttcaa tatccagctc acgccgttct tcgataagat
    10081 cggcgcggat ttgatcggcg tgcgctttcg tcgccagcca gccaatcacc gccccagccg
    10141 ccagcgccac gacggcgctt atcataagag taatatccac aacacctctc ctggaaccac
    10201 actgtcctgc acaaaataga attgtgctgt ataaacgtcc agtttaaaag ggatttcctg
    10261 cgaggcgcca cgcaaaaaga aaaggccgaa cgcgtcggcc tttgcaaaag agaggagaat
    10321 tacagcagac gacgggccgc ttccacgaca attttcaccg cgtggctttc agtttgtttc
    10381 atcgtttccg cattcggaat ctcttgttgg gtacggttaa cgataacgcc cgccaccata
    10441 cctgcgcgta aaccctggct tgcgcacatg gttaacagcg tagcggattc catttcgtag
    10501 ttcatcacgc ccattgcctg ccactcttcc atagagcctt tgaagcgacg aacaacgcgg
    10561 ccagaatagg tgtcgtaacg ttcctgaccc ggatagaaag tgtcggaaga ggcggttacg
    10621 ccaacgtgag tcgtggcgcc aatcgatttc gcggcttcaa ccagcgcggt ggtgcaggca
    10681 aagtcggcaa ccgccgggaa ttccatcggc gcaaaatgca ggcttgcccc atccagacgt
    10741 acggatgcgg tcgttaccag aacgtcgccg acgttgatgt gcggctgaat agcccccgtg
    10801 gtgccgatac gcaagaaggt acgaataccc agttgcgcca gttcttccac ggcaatagag
    10861 gtagacgggc cgccgatacc ggtagagcaa acgataactg ctttaccatc cagctcagcg
    10921 cgccaggagg tgaattcgcg gtgagatgcc agcttaaccg gcttatccat cagcgcggcg
    10981 atcttttcca cacgctcagg atcgccaggg acgatggcga gctgggcccc ttgtaaatcg
    11041 tttttggtga ggccgagatg aaaaacatca gacttggaca tataaaactc ctctgtgaat
    11101 cgggtttgtc agaagaagca aaaagacact ttacctaagg cataaagata ttttcgtgac
    11161 agccatcact atggcgtaaa acaattgcac tcgtttacca ttaaaaagtg atgtgcatca
    11221 caataaataa tcaatatcgc caagcattgc acaaaagata gccgctttaa ggcaatgtgg
    11281 tttgttacac actgtctata gttaagattg cgctattttt taagggtacg gagaatacca
    11341 tgacaacgac acatccatcc ggctttgcac ctgcagcttc cccacttgcc cctacgatga
    11401 ttcatacacc tgatggggcc attagcgcgg ggataacgtc gatcccctct cagggcgacg
    11461 atatgccagc ctattacgcc agaccaaagg caagcgacgg cgcgctgcct gtggtcattg
    11521 tggtacagga aatttttggc gtacatgaac acattcgcga tatttgccga cgactggcgc
    11581 tggaaggcta tctcgctatc gcgccggagc tctatttccg cgaaggcgac cccaatgatt
    11641 tcgccgatat acccacatta ttgagcgggc tggtggctaa agtacccgat tcgcaagtcc
    11701 ttgccgacct ggatcacgtc gccagttggg cttcgcgcaa cggcggggat gcgcatcggc
    11761 tgatgatcac cggtttttgt tggggaggcc ggattacctg gctatacgcc gcgcacaacc
    11821 cacagttaaa agcagcggta gcgtggtacg gcaagctggt gggcgacacg tcactcaatt
    11881 cgccgaagca tcccgttgat atcgccaccg atcttaacgc gccggtactg ggtttatacg
    11941 gcgggcagga taccagtatt ccacaggaga gcgtggaaac catgcgtcag gcgctacgcg
    12001 ccgctaatgc gaaggcggaa atcgtggtct atcccgatgc agggcacgcg tttaatgccg
    12061 attatcgtcc gggctaccac gaagcctcag cgaaagacgg ctggcaaaga atgttggaat
    12121 ggttcgcgca gtacggtggg aaaaaaggct aaccacagcg cattacgatg tttgttgggc
    12181 ctacgagacc ggagtcggtg taggctcaac aaatcgtcat cgccacgtta gctatgcttt
    12241 accacagcat ttttatattt tttgccgctg ccgcagggac agagatggtt acgactgacg
    12301 gctcctgtgt ctttacgcgc gtcctgcgcc agccagcgca tgatcgatgc catcggatag
    12361 ccttgcgcca gcagctcccg ccagacattc atatacggcg taacgtgctg gaaaaaatgt
    12421 ttatagcccg tacacaagta attatgcgca ggatgaccgg acggcgagac ggcaaagcga
    12481 tgcttcggac agccgccatg acacgcaaag cggtagtcac agcgacgaca atcggcggtc
    12541 agggtctccc gcttggcctc gccaaacgca atagcccgct cgctattatt taaggttttg
    12601 atgctgtgct ggtggatatt ccccagcaga tgctccgggt agacaaagtg gtcacagttg
    12661 tagagatcgc cgttcgactc caacgcgaag gcatgtccac aagtctcgga atgtacacac
    12721 agtaccggct gctgcgccgt ccaggcggct aacgccacgt caaacatctg cacatagacg
    12781 cggtctacgt cgcgacgaac ccagatatca aagatctggt tgagaaattc gccatattgc
    12841 cacgacggta ccgtccatgg cgccagcttt gccgcgcttt cgccgggcat caccagatta
    12901 agtaccgatg agttatcggt gctcattcgc tctaccagcg ggataaactg aataaaacgc
    12961 gatcccgccg ccagaagaaa ttcgtagacg tctgctgcat gaccgacgtt atgttttccc
    13021 acgacggtta aggtattaaa gtcaacatgg tgcgctttaa gccgcgccat ggctgcgacg
    13081 acctgttcat gagttccttt tccagcgcga ttaagccgat agtggttgtg taacgacgcc
    13141 ggaccgtcga tagagagacc gatgagaaaa tgctgttcag cgaaaaagcg cgcccactcg
    13201 tcattcacca ggatgccgtt cgtctgtaac gcatgagtga tttttcgccc atcgccgtac
    13261 ttttcacaca atgcgacaac ccggcggaaa aatggcagcc ccatcatggt cggttcgccg
    13321 cactgccagg caaagtcaat gcggtcgcca ctctgcgcgg caatatgctg gcgtataaac
    13381 tgttccagcg tctcgtccga cattcgccag tttttattgc gttccgggta cagcgcctct
    13441 ttttcaagat agaagcaata tgtgcaatca atattgcaga tcgcgccgcc gggtttggcc
    13501 attacgtgac aacctgctac cgccatgtca gacatctccg ttaaaaaata aggttcacca
    13561 gcgccatgag acaatgcgac gtttatcgtc gccagggaac ataacagaat ggaaaacctc
    13621 gttttgtgct atgagagcgc tgggcgatca tgacaggaaa aacgatctgc gaggcaataa
    13681 aatccgccgc gctgcttccg gggacgctat ccgcctggtt gtcattcata cggagaacct
    13741 ttttattatc aagatcgcca aatagccaga tcctgaaaaa gacagcgcgg aaaataagaa
    13801 aaagggaaat gagaagaaag aggcgctgtt aatcaggtca gacacgggcg ctacccgtca
    13861 aagggtagcg ccgcattgct gccggataaa cgcagcggtc aggatgggtt atttcgcctg
    13921 acgcagattg tgcgccgctt tgaccatgtt cgctaacgcc gcgcgggttt ccggccaacc
    13981 gcgagttttc agaccgcagt ccggattcac ccacaggcgt tgtgccggaa tacgttgtgc
    14041 cgccttcttc agcagggctt caatccactc gacgctcggc acgttcggcg agtgaatatc
    14101 gtacacgccc ggcccgattt cgttcgggta gtcgaacgct tcgaacgact ccagcaactc
    14161 catatccgag cgggaggtct caatggtgat cacatccgcg tccagcgcgg cgatcgaatc
    14221 cataatgtcg ttgaactcgc agtaacacat gtgggtgtgg atctgggttt catccttcgc
    14281 caccgccgcg ttgatgcgga aggcttccac accccattcc agataggcgt cccagtcgct
    14341 gcgacgcagc ggtaaacctt cacgcagcgc cggttcgtca atctgaataa tcccgatccc
    14401 cgccgcctcc agatccgcga cttcatcacg cagcgccagc gcaatctgtt tcgcaatcgt
    14461 ttcgcgggtc acgtcttcgc gggggaatga ccagcaaaga atagtcaccg ggccggtcaa
    14521 catccctttt accggcttgt cggtcagcga ctgggcatat ttcgcccact ccacggtaat
    14581 cggtgccgga cggctgatat cgccaatcac taccggcggt ttcacacagc gggagccata
    14641 gctttgcacc caaccattct gggtaaagac gaagccgtcc agatgctcgc cgaagtattc
    14701 caccatgtcg tttcgctcgg cttcgccgtg taccagcaca tccagcccta aacgctcctg
    14761 ctcgatgata gcctgtttga tatgttcggc gatgccggtg cggtagttgt tcgcgtcgag
    14821 gttgcccttt ttgaagtcca gacgcaggcc gcgaatttcc gtggtttgcg gaaacgaacc
    14881 gatagtcgtc gtcggccagg cgggaagttt aaagcgggcg cgttgcgctt cagcgcgcac
    14941 ctcatacgga ttctcacgct ggctgtcctg cgcggtgatc gccgccaggc gtttttctac
    15001 tgcggcatta tgtacgcgat gggagtgacg acgagcctga atcggtacgc tccattcctc
    15061 aagcgccgcc gtttcgccgc tgttcagcgc atcgcgcagc aacgccagtt caccgcattt
    15121 ttgcagcgca aaggcaaacc agctttttac ttccgtatcc agacgcgttt cgacgctgag
    15181 atcgatcggg ctgtgcagta aagagcagga ggatgctacc cacagcgcgc gtttgcccac
    15241 aatggcgtta atctgcgcgt atttttcggt caaatcggcg cgccagacat tacgcccgtt
    15301 aatcaagcct gcggagagca gccagtcgac cggcagacgt tgatgcagtt ccactacatc
    15361 atctttgcca tgaatgaggt caacatgtag cccctgtacc ggtagcacga taatagtgtc
    15421 caggtttggc gtcacgcctt caaaataggt cgtcagcaac agcttcacct ggccggcgag
    15481 cgcgtcgtaa gccggtttga aggcatccag ccacgcctgc ggcagttcca gcaccagtgc
    15541 tggctcatca atttggaccc actcaacacc acgcttcgcc agctcagcca gcacgtgctg
    15601 atacaccggc aaaatgtctt tcagcaacgt caggcggtca aacggctcgc ctttcacttt
    15661 acccagccac agatacgtga caggccccag cagtacgggt ttgatcttat gccccagcgc
    15721 cagcgcttcg tccacttcct ccagcaactg tgtccaggta agcctgaact gctggccttt
    15781 gctgaactcc ggtactatgt agtgatagtt agtattaaac catttggtca tttccgctgc
    15841 cgccgccggt tcgccggttg gcgcgcgacc acggccaatg cggaacagag tgtcgatgtc
    15901 cacggaaccg tcgttgttct gatgacgagc cggcacattg cctaacagca ggctggtggt
    15961 cagaacatgg tcgtaccagg caaagtcgcc taccggtaac aggtcaatac ccgcttgttt
    16021 ctgctgctcc cagtgacgcg cgcgcagttc gcggcccacc gccagtaacg cttcacgcgt
    16081 tgtgttcccc gcccagtagc tctcttgcgc ttttttcaac tcgcgacgca ggccaacgcg
    16141 aggaaaaccg agggtatgag tcaatattgt cattttactt cctctcttat tttattgaat
    16201 ctgaaagtaa aactctaaat agttcggctt gcaggaaggc ggcgacacag cgcatcccca
    16261 ggagcttact gaagtaagtg actggggtaa gcaaggaagc caacgcatct gcaagtcgaa
    16321 atatgacgag ttttagacgt ctggatgttt acacatccat aatgtaaagg tactgtatat
    16381 tcctcaagcg caatttgttc atggcgaagt gaaggacttt catgatcgaa attaaacatc
    16441 tgaaaacact ccaggcattg cggaatagtg gatcgctggc tgctgctgct gcggtgctgc
    16501 accagactca atccgctctg tctcatcagt tcagcgatct ggaacaacgc cttggcttcc
    16561 gcctgttcgt gcgtaaaagc cagccgctgc gctttacgcc gcagggggaa gttctgctgc
    16621 aactggcaaa ccaggtgctg ccgcaaatca gccgtgcgct gcaggcgtgc aacgaaccgc
    16681 agcaaactcg tctgcgcatc gctattgaat gtcatagctg tattcagtgg ctgaccccgg
    16741 cgctggaaaa cttccgtgca agctggccgc aggtagaaat ggatttcaca tccggcgtca
    16801 cttttgatcc gcaaccggcc ttgcaacaag gcgagctgga tttggtgatg acgtcggata
    16861 ttttgccgcg cagcgggctg cattattcgc cgatgtttga ttttgaagtc cgactggtgc
    16921 tggcgcccga ccatccgctg gccagcaaaa cgcagattac gccggaagat ttagccagcg
    16981 aaacgctgtt gatttacccg gtgcagcgca gccggctgga tgtctggcga catttcctgc
    17041 aaccggcggg tatcagtccg ctgctgaaaa gcgtggataa tactctactg ctgattcaga
    17101 tggtggcggc cagaatgggt attgccgccc tgccgcactg ggtggtggaa agcgttgagc
    17161 gccagggtct ggtggtgacc aaaaccctgg gcgatggtct gtggagccgc ctgtatgccg
    17221 ccgtgcgcga cggcgaccag cgtcaggcgg tgaccgaggc gtttattcgc tcgacgcggg
    17281 atcacgcctg cgatcatctg ccgtttgtgc ggagcgcgga gcgacccatt ttcgatgcac
    17341 ccacagcgaa gccaggatca cagccgcgcc tgtaataaag cttggccagt ggggctgctg
    17401 atgccagatg gcaagattaa ccagcagtcc tgcgggaaca tgcatattat tcatgatacc
    17461 cagcgtcccg gcgtctacct gggtagcgcc atagttccac ataaagtagc caatgccgga
    17521 cgccaccacg ccgagaaaca ccagaatgct ccattgcagc gtggtttccg gcagcttttg
    17581 cgcgttcccc aacagcgacc acgccaccgc cgccaccaaa aacgccccca gatagaacca
    17641 cgcaaaggcg ttgtgctgcg gcatgggacg ggtctccatc agacgtttat accccaccat
    17701 tccgatagcg aaactgatat tagaaagctg caccaggagc aaaccgaccc aaaaatggtc
    17761 ggtcacgcga tcgtagcgaa taatcccggc gccaatcacc gccagcaacg cgctaaatgc
    17821 atagccccag cgcaaacgac gctgactcat cacatcgtaa atcagcgtga tatagagcgg
    17881 cgtcaaaacg gtaaacagca gcagttcgga tacggtcagg tagaggtaag catggaagct
    17941 caacatatac atgatgccaa gctgcatcgc ccccaccagc atatacaggc tgatggtttt
    18001 taggttgtgc ccgcgagtac gcaaaaacgg cagaaaaacg agcgccgcca gcccaacgcg
    18061 tatcagcacc gcgaaatagc tatcgacatg cccggcaaga tactcgccaa atagactaaa
    18121 ggagaaagcc cacaggatag tggtgatgat gagtagcgcc acaatggatg tctcttaaaa
    18181 cagggaacac ccattgtagc ggagagtgag gttgacaact ggtcaactaa caaacaatca
    18241 catcagcgta agaaaagatc gcgcaggtaa tgcggcacgg cgttatccgc gttgatgccg
    18301 atcacctcaa gttcgggata caggtctttc agacgctggt gcgcattgcc catgatgcag
    18361 cctttgcccg ccatcgtgag catttcagcg tcgttcattc cgtcgccaaa ggcgatacac
    18421 tctttcaggc tgtaccccat cgcctgagcg accgcttcca gcgcatgacc tttcgacact
    18481 ccgcccgcca tcacttccag acaggttagc gtagagaagc tcacgtttac ccgatcgccc
    18541 cagcgcgcgt taatcgcctg ctccagcggc aacaactttt catgagtgtc gctggtgaaa
    18601 aacactttgc tgacgccctc cggctccagc agcgcaggct caaacagcga atagttaaat
    18661 accgcctctt tgaaaaaacg catttcatcg gggcgatgac gattcataaa ccattcgtcg
    18721 tcgcgataaa cgttagtcac gatgtccggg ttcgcattca ccacgccgaa caggtcgctg
    18781 gcaatgtcgc tgtccagatt atgcgtaaaa accaaattcc cgtcggtatc gtgcactcgc
    18841 gcgccgttgg aggtgatcat gtaagacttg atttcaagat tatcgcggat ttgccctaca
    18901 tcgacatgat gacgaccagt ggcaaagaca aaatggatgc cgcgtgcggt caacagcttc
    18961 agagtctctt tggcataagg ggacaacgta tggtcggggg agagcagcgt gccatctaaa
    19021 tcagacgcaa caacctgata cataataaaa tttaacctct aagcaaagcg atttccgctg
    19081 gataaattag gcttgttgaa aaattcaaca atggcgttaa gcgcgactga gcgcatggcg
    19141 tccttttcaa aaaggatctc atggtacgcg cctttgataa ccagcggttt tcccccttca
    19201 caagggtatc ccgccgcggc gcgaatttca caaaaacgat cgtgggtgcg gttatccact
    19261 acccgctctt cttccgcctg aatcagtagc gtaggcgtcg tgtcatcgct cgccccagcc
    19321 agtacctgct cacccgccag aatgccttcg cgtacccaat gccaggtggg gccgccaacg
    19381 cgcagctgcg gctcgtcggc ataaaatcgt aagttgcgct gataacgctg gcggctgtgg
    19441 gtcagcgcat tcatcccaaa cggcaacgcc cgccactgac cggtaccaat agcgtaatct
    19501 tcacggatac gctgatgccc ttcggcccag tcgagaatat ggcgcaccat aaaggaaggc
    19561 aagcgtatca caataccaaa catcggcgcg gtgagcgcaa tagcgtcgca ccgcacacga
    19621 tggcgttgca ggaacagggt ggctatcgcg ccccccattg agtgcgccag gatataacgc
    19681 ttacgccacg accccggctc aatttcctgc tgccagaacg ccgctaagtc ctcaacataa
    19741 tcgttaaaat gatcgacatg accccgatgc gggtccgata acatccgccc ggagcgccct
    19801 tgaccacggt ggtcgatgat gaagatatca aaaccgagat gaaaaaggtc atacgccagt
    19861 tcagcgtatt ttacataact ctcaatgcgg ccaggacaaa tgacgatcgt ccgatcgttg
    19921 gagtcattcc gaaaacggac aaagcgcacc ggaatgttat ccacgccgat aaactccgcc
    19981 tcttcccgct gacgccaaaa atcggtcagc ggccccatag caaaagcggc aaacgcattt
    20041 tctcttgttt cccagtcatt ttgctgctga aacatcgggt tttcggcctc gtttaccagg
    20101 taaaatcgtt ttttgcgtcg tgcctgacac aacacagcgg cagtagcgta ttgtggcaca
    20161 aaaacagaca accaaggagt ttcgcatgac ctttgaatgg tggttcgcct atctactgac
    20221 ctcaactctg ttgagtcttt ctccgggttc aggcgccatc aataccatga cgacgtctat
    20281 caaccatgga tatcgtggcg cagcggcttc tatcgccggg ctccagaccg ggctggggat
    20341 acatatcgta ctggtgggcg tcggactggg tacgctcttt tcgcgctcgc tcatcgcttt
    20401 tgaaattctg aaatgggctg gcgcggctta tcttatctgg ctgggtatcc agcaatggcg
    20461 cgccgcaggc gctatcgatc tgcatactct cgcccagacg caatcgcggg gtcggctgtt
    20521 caaacgggcg atatttgtca atctaaccaa tcccaaaagt attgtctttc ttgccgccct
    20581 gtttccgcaa ttcatcatgc cgcagcaacc gcaactggcg cagtacctca ttctcggcgt
    20641 caccacgatt gtggtggata tgattgtgat gaccggttac gccacgctgg cgcagcgcat
    20701 tgccgcctgg attaaaggac caaagcagat gaaggcgctg aataaagcgt ttggttcgtt
    20761 gtttatgctg gtaggcgcgc tcctggcgtc ggcaagacac gcgtgatagt cgtgccggat
    20821 gatgtttatc cggcccggag gtaaattaac gcgaaataat caggtgaata ccaaagcccg
    20881 caaacagagc gccggcaaag ccatcaatcc atttcgccag acgctgatag ccacggcgca
    20941 ttttcggcag cgcgaacagg ctggcgacta cggtaaacca ggccagcgtt tccagggtaa
    21001 ttaacgcgaa aataccccag cgcgccgcag cgccgacgtt atcgccgaca aacagtgaaa
    21061 aaacggaacc aaaatagata atcgctttcg gattcgacag attggtcagc agccctttga
    21121 gaaaactgcg cccgctctgc gccagttcaa tgtgcggaga agacgccgcc gcatcctgtt
    21181 ttttcagcgc gccgcgcagc atctgatagc ccatccagca caggtacagg ccgccgccta
    21241 ccataatgat cgtatgcagc caggccattt tttcgatgat gagatgcagg ccaagcagcg
    21301 ccacgcccgc ccataccatc acgccgcagg tgatgcccag tacgcccatc atcgcttctt
    21361 tacgcgaacg gctgacggca gtttgagaca cgaagaaaaa atcggggcca gggctcatta
    21421 gcgcaacgat gtgcaccatt gccacggtga aaaatagcat caacataaaa atggctcgcg
    21481 gggaaatagt tcagtgagtc accatcctgg cacttttttg ccgggctgac tactcttcgt
    21541 catcaccatc gacatgcgcg cggatgagcg ccatgaattc tttcccgaag cgctccagtt
    21601 tgcgcatccc aaccccgtta acgcttaaca tctcgctggc ggaaaccggc atctgttccg
    21661 ccatttctat caacgtggcg tcgttaaaga ccacatacgg cgggatattc tcttcatcag
    21721 cgatagcttt acgcagcttg cgcaacttag cgaacaattt gcgatcgtaa ttaccgccga
    21781 acgatttctg catcacgcgg ggtttgaggg cgacaatgcg cggcaccgca agctttagcg
    21841 gaacgtctcc acggagtacc ggacgcgcgg catccgtcaa ctgtaatgcg gagtgctgcg
    21901 caatattttg cattaccagc cccagatgaa tgagctggcg aatcacgctc acccagtgct
    21961 catggctctt ttcgcgtccc atgccataaa ccttgagttt gtcatgaccg aaatcgcgga
    22021 tgcgttggtt attcgcgccg cggatcacct cgacaacgta gcccatgcca aaacgctggt
    22081 taacccgacc aatggtagaa agcgcaatct gggcatcgtt taagccatca tattgtttgg
    22141 gcggatcgag acagatatcg cagttgccgc acggttcttg tcggccttcg ccaaagtaat
    22201 taagcaatac caggcggcgg caggtttgcg cttcggcaaa agcgcccatc gcattcagct
    22261 tatgccgttc aatatcctga agctgtccgg ctggtttctc ttccagacaa cgacgtagcc
    22321 aggccatatc agccggatcg taaaatagca tggcttccgc aggcagtccg tcgcgcccgg
    22381 cgcggcccgt ttcctgatag taggattcaa tattacgcgg gatatcgaaa tgcacgacga
    22441 aacgtacgtt aggtttgttt atgcccattc caaaagcgac ggtcgccacc acgatttgca
    22501 gatcgtcgcg ctgaaatttt tcctgcacat cggcgcgaat agcgttttcc agccccgcat
    22561 gataggccgc cgcgctaatg ccgcgacttt gcaagcgcgc ggcggtatct tccactttcg
    22621 cccgactgtt gcagtagatg atacccgatt tgccgcgttg ctcctgaaca tagcgcatta
    22681 gctggtcgag cggcttaaac ttctccatca gcatgtagcg gatattcggt cggtcaaagc
    22741 tactgatctg gattaacgga tcgttaagcc caagcagacg aataatatcc tggcgcgtgg
    22801 tgtcgtcggc ggtggcggtc aatgccataa acggcaaagc gggaaaacgc tggcgaagct
    22861 gaccgagagc cgcatattcc ggacggaaat catgtcccca ttgcgagata cagtgcgctt
    22921 catccaccgc cagcaatacc ggattccagt gcgccagatg atcaagaaag ttgtccagca
    22981 tcaggcgttc cggcgcaata tacagcagac gaatctgtcc ggtacggcac cccgccatca
    23041 cctcaagctg ctgctcgcgg ctttgagtgg agttcagaca ggccgccgcc accccgttcg
    23101 ccagtagctg atcgacctgg tctttcatca acgagatcag gggcgaaacg acgacggtca
    23161 atccgtccag caacaacgcg gggatttgat agcacagaga tttgccgccg ccggtgggca
    23221 tgacgaccag acagtcgcga ccggagagcg cagtatcaat aatcgcttcc tggcccgggc
    23281 gaaactgttg gtagccaaag gtttcctgca aaacctgttt ggcccctgat tccagattca
    23341 acacttccgc ctgcgccaca ttaaccccgt tcaccataaa tcaaaacagg cgctattttc
    23401 agcgcctgcg agagaaactg caatgtttaa aacacaatcc aatcagaaga tatcgttaag
    23461 catcacgccg acgccgacac gtgtctgatt aaaattatag tcgatcagcg attcgccata
    23521 gccgctatac acctgggtat aaagccggac atgtttagtg accggatagc ttaatccaac
    23581 ttccgcgccg ccgtagcctg tattccagtt gtactggcct ttggcgctta ataccgcctc
    23641 gcccaggtga taaccgattt taagctggta ataacccata tatttggtga tgtccggatt
    23701 atcgtcggta ctgccaatca cgtaccatgg tttgacctct accagccagt taccgttttc
    23761 ggccatcaga cgggtataca gacggttcca gctacgcgag gtggggtccg aacgtccgtt
    23821 agagtcatgg ttgtagccca tctctacgtc gcgcagcgtc cagccggcaa agcgataatc
    23881 ggtagcaaaa ccaagaaaaa gctgcggttc gtagttggtt tcgcgaaacg gcgaagactc
    23941 tttactgttg gaaagctgcc accaggattt ctgcgtatag gaagcgccca gtaccgagtt
    24001 cggccccagt attccgcgcc acagcggaaa cgccaggctc aactgaaatt tcacttcatc
    24061 tttacgtgcg ttttcagacc agttgtaggt acttatggcc tctttgttca gatcgctggt
    24121 gttcgtgtag atcaagtagt tcgtgtcata agggtaaagc gtaaaagggt tatcatgctc
    24181 ctgtagcatg ttagcgatga tacttccccg tactgcaggc gcatcatgaa cctcttttat
    24241 cgtagcttct tgtgcatatg ccgctaatgg cagtagcgtg gctggcaaca accctctcaa
    24301 aatcgcccgc attcttgacg ttctcctgac gaagtatttt cagcttgaat cattctctgc
    24361 caaccatttt tacatattta cacacatagc cgttagttat cccttcttaa agtagaaaac
    24421 aacaattaag aagcataata tcaacatttc attaaccaat ggagtatcag gaatctatgt
    24481 ccgctgtact taccgctgaa caagctctga aattagtggg tgaaatgttt gtctaccaca
    24541 tgccgtttaa tcgggcgtta gggctggagc tggaacgcta tgaaaaagcg ttcgcccaac
    24601 tggccttcaa caaccagccg atgatggtcg gcaactgggc gcaaagcatt ttacacggcg
    24661 gcgtgatcgc ctctgcgctg gatgtcgccg ccggactggt atgcgtcggc agcacgctaa
    24721 ctcgccacga aaccatcagc gaagatgaac tacgccagcg cctgtcgcgg atgggaacga
    24781 ttgacctgcg cgtcgattac ctgcgtccgg gcagaggcaa ccgctttacg gccaccagta
    24841 gcctgctgcg cgcagggaat aaagtggccg tcgcccgcgt ggaattacac aatgaagatc
    24901 agctgtacat cgccagcgcc accgctactt atatggtggg ataaaagcag gtaaactgtt
    24961 gttacacttc agatacgagt tttccggatg gacgcaaaac aaacacggca gggcgtatta
    25021 ctcgctcttg ccgcctattt tatttggggg atcgcccccg catatttcaa gctgatctat
    25081 tacgttcccg cagatgagat cctgacgcac cgcgtgattt ggtcattttt ctttatggtg
    25141 gcgctgctta gcgtcagccg gcagtggcga caggttaagc gtttactgaa aacgccaaag
    25201 aagattttcc tgctggccct gtccgccgta ctggtcggcg gtaactggct attgttcatt
    25261 tgggcggtaa ataatcacca tatgctggag gccagcctgg gttatttcat taatccgctg
    25321 gttaacatct tgctggggat gatttttctt ggcgaacgct tccgtcgaat gcagtggctg
    25381 gcggtgattc tggcggtgtg cggcgtgctg gtgcaactct ggacctttgg ctcgctgccg
    25441 attatcgcgc tggggctggc gtttagtttt gcgttttacg gcctggtgcg taagaagatc
    25501 gccgttgaag cgcagacggg tatgctggtc gaaacgctat ggctgttgcc ggtcgccgcg
    25561 atttatctgt ttagcatcgc cgatagcgcc accagccata tggggcaaaa cgcactatcg
    25621 ttgaacttgc tgttaatggc ggcgggtgtg gtcactacga ttccgctgct gtgctttacc
    25681 ggagcggcta cgcgtctgcg tctttctaca ctgggctttt tccagtatat cggcccaacg
    25741 ctgatgtttt tactggcggt gacgttttat ggcgaagtgc cgggcgcgga taagatggtg
    25801 acatttgcgt ttatctgggt cgcgctggcg attttcgtga tggatgcgat ttatacgcag
    25861 cgtaaaaaat aacgcgacta ttattctaaa tataatctga aaaaatatgc ctccccttgt
    25921 aaggggggta gcatattgtc atgctaacga cgtaacccaa catatggatg tgaaattaat
    25981 gttaagtgtt tttattcctt catctgagag atgtgtttcc agatgtcgtt atttattatc
    26041 attcgcgcta ataaatataa tattttccat tttggttggg gttttattat atttaagctt
    26101 tgtgatactg gcaattttat tcacaatttt actacattat ctcgtcatta atttaaac
//
LOCUS       DAJVKX010000056        25751 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000056 DAJVKX010000000
VERSION     DAJVKX010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 25751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25751
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.056"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..2652
                     /gene="sadA"
                     /locus_tag="OPY25_002401"
     CDS             <1..2652
                     /gene="sadA"
                     /locus_tag="OPY25_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric autotransporter adhesin SadA"
                     /protein_id="HCS0928003.1"
                     /translation="NTADITTNTNSINQNTTDIATNTTSINNLSNSVTTLTDDALLWD
                     ADSGTFSASRNGSASKITNLAAGTLAADSTDAVNGSQLYETNQKVDQNTSAIADINTS
                     ITNLSSDNLSWNETTNSFSASHGSSTTNKITNVAAGELSEESTDAVNGSQLFETNEKV
                     DQNTTDIAANTTNITQNSTAIENLNTSVSDINTSITGLTDNALLWDEDTGAFSANHGG
                     STSKITNVAAGALSEDSTDAVNGSQLYETNQKVDQNTSAIADINTSITNLGTDALSWD
                     DEEGAFSASHGTSGTNKITNVAAGEIASDSTDAINGSQLYETNMLISQYNESISQLAG
                     DTSETYITENGTGVKYIRTNDNGLEGQDAYATGNGATAVGYDAVASGAGCLALGQNSS
                     SSIEGSIALGSGSTSNRAITTGIRETSATSDGVVIGYNTTDRELLGALSLGTDGESYR
                     QITNVADGSEAQDAVTVRQLQNAIGAVTTTPTKYYHANSTEEDSLAVGTDSLAMGAKT
                     IVNADAGIGIGLNTLVMADAINGIAIGSNARANHANSIAMGNGSQTTRGAQTDYTAYN
                     MDTPQNSVGEFSVGSEDGQRQITNVAAGSADTDAVNVGQLKVTDAQVSRNTQSITNLN
                     TQVSNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGADANAQGADSVAIGSGSIAAAEN
                     SVALGTNSVADEANTVSVGSSTQQRRITNVAAGVNNTDAVNVAQLKASEAGSVRYETN
                     ADGSVNYSVLNLGDGSGGTTRIGNVSAAVNDTDAVNYAQLKRSVEEANTYTDQKMGEM
                     NSKIKGIENKMSGGIASAMAMAGLPQAYAPGANMTSIAGGTFNGESAVAIGVSMVSES
                     GGWVYKLQGTSNSQGDYSAAIGAGFQW"
     gene            2951..4606
                     /gene="lldP"
                     /locus_tag="OPY25_002402"
     CDS             2951..4606
                     /gene="lldP"
                     /locus_tag="OPY25_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HCS0928004.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVVIALAVALLFYKMPVDHALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFNPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTDLDSFEIGQMVGRQLPFLTIIVLFWIMAIMDGWR
                     GVKETWPAVMVAGGSFAIAQYLSSNFIGPELPDIISSLVSLVCLTLFLKRWQPVRIFR
                     FGDMGASQVDQTLARTRYTTGQIVRAWSPFLFLTATVTLWSIPPFKALFAPGGALYDW
                     VINVPVPYLDKLVARMPPVVHEATAYAAVYKFDWFSATGTAILFAALLSIVWLKMKPS
                     AAIQTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGSAFTFFSPFLG
                     WLGVFLTGSDTSSNALFASLQATAAQQIGVSDVLMVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP"
     gene            4603..5379
                     /gene="lldR"
                     /locus_tag="OPY25_002403"
     CDS             4603..5379
                     /gene="lldR"
                     /locus_tag="OPY25_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HCS0928005.1"
                     /translation="MIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVS
                     RNSLREALAKLVSEGVLVSRRGGGTFVRWQHETWSEQNIVQPLKMLMANDPDYSFDIL
                     EARHAIEASTAWHAAMRATAADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHN
                     VVLLQTMRGFFDVLQSSVKQSRQRMYLVPPVFSKLTEQHQAVLDAILDGNAEGARKAM
                     MAHLSFVHTTIKRFDEDQARQARITRLPGDHNEMTRENKS"
     gene            5376..6566
                     /gene="lldD"
                     /locus_tag="OPY25_002404"
     CDS             5376..6566
                     /gene="lldD"
                     /locus_tag="OPY25_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent L-lactate dehydrogenase LldD"
                     /protein_id="HCS0928006.1"
                     /translation="MIISATSDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQ
                     VALRQRVLKNMSDLSLETTLFNETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIP
                     FTLSTVSVCPIEEVAPTLKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLY
                     ALATAGKTGVANLLDLIEKEMKVAMTLTGAKSISEISGDSLVQELGKSLPAALAPMSK
                     GDAA"
     gene            6631..7104
                     /gene="trmL"
                     /locus_tag="OPY25_002405"
     CDS             6631..7104
                     /gene="trmL"
                     /locus_tag="OPY25_002405"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCS0928007.1"
                     /translation="MLNIVLFEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFAAVQRHHDYAAFVAAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPKEQKIRIPMMPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRS"
     gene            complement(7172..8176)
                     /locus_tag="OPY25_002406"
     CDS             complement(7172..8176)
                     /locus_tag="OPY25_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCS0928008.1"
                     /translation="MKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEKV
                     MQAVRVTGYIPNALAGGLASRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILL
                     CVAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVILNAAIPVVEIWDLTPTPL
                     DMLVGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQ
                     VDVPLPASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIG
                     FGDLDFAASNRPSITTVSVDRRAIGQRAATLLADRIEQKPCAEAIVDIGFHLIERESA
                     "
     gene            8495..9691
                     /locus_tag="OPY25_002407"
     CDS             8495..9691
                     /locus_tag="OPY25_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-talarate/galactarate dehydratase"
                     /protein_id="HCS0928009.1"
                     /translation="MALSANSDAVTYAKAANTRTAAETGDRIEWVKLSLAFLPLATPV
                     SDAKVLTGRQKPLTEVAIIIAEIRSRDGFEGVGFSYSKRAGGQSIYAHAKEIADNLLG
                     EDPNDIDKIYTKLLWAGASVGRSGMAVQAISPIDIALWDMKAKRAGLPLAKLLGAHRD
                     SVQCYNTSGGFLHTPLDQVLKNVVISRENGIGGIKLKVGQPNCAEDIRRLTAVREALG
                     DEFPLMVDANQQWDRETAIRMGRKMEQFNLIWIEEPLDAYDIEGHAQLAAALDTPIAT
                     GEMLTSFREHEQLILGNASDFVQPDAPRVGGISPFLKIMDLAAKHGRKLAPHFAMEVH
                     LHLSAAYPLEPWLEHFEWLNPLFNEQLELRDGRMWISDRHGLGFTLSEQARRWTQLTC
                     EFGKRP"
     gene            9765..11075
                     /locus_tag="OPY25_002408"
                     /pseudo
     CDS             9765..11075
                     /locus_tag="OPY25_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462598.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(11158..11979)
                     /gene="cysE"
                     /locus_tag="OPY25_002409"
     CDS             complement(11158..11979)
                     /gene="cysE"
                     /locus_tag="OPY25_002409"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCS0928010.1"
                     /translation="MPCEELEIVWKNIKAEARALADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLASPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNKGRRALAIFLQNQVSVSFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIEDDVSILQSVTLGGTGKTSGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPGSDKPSMDMDQHFNGLHHTFEYGDGI"
     gene            complement(12057..13076)
                     /gene="gpsA"
                     /locus_tag="OPY25_002410"
     CDS             complement(12057..13076)
                     /gene="gpsA"
                     /locus_tag="OPY25_002410"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCS0928011.1"
                     /translation="MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATL
                     EHDRCNVAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFSDVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     ETFADDLQQLLHCGKSFRVYINADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLTEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGA
                     QDKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKE
                     ELSRH"
     gene            complement(13076..13543)
                     /gene="secB"
                     /locus_tag="OPY25_002411"
     CDS             complement(13076..13543)
                     /gene="secB"
                     /locus_tag="OPY25_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HCS0928012.1"
                     /translation="MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDL
                     DTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYC
                     PNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(13587..13838)
                     /gene="grxC"
                     /locus_tag="OPY25_002412"
     CDS             complement(13587..13838)
                     /gene="grxC"
                     /locus_tag="OPY25_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HCS0928013.1"
                     /translation="MANIEIYTKATCPFCHRAKALLNSKGVSFQEIAIDGDAVKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLR"
     gene            complement(13924..14355)
                     /locus_tag="OPY25_002413"
     CDS             complement(13924..14355)
                     /locus_tag="OPY25_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCS0928014.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLFTTFKGLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGATNLLPSEIKANNVGELEKHKDKPIIVVDG
                     SGMQCQESANALTKAGFEKVFVLKEGVAGWSGENLPLVRGK"
     gene            14603..16147
                     /gene="gpmM"
                     /locus_tag="OPY25_002414"
                     /gene_synonym="pgmI"
     CDS             14603..16147
                     /gene="gpmM"
                     /locus_tag="OPY25_002414"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HCS0928015.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAILNAKTPVMDALWAKRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKERTFFANPVLTNA
                     VDQAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAEASLKKFEDKFAALGKGRVASIVGRYYAMDRDNRWDRVEKAYDLMTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQADAAMEDGDTLIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNLNFVMLTEYAADIKTAVAYPPASLANTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEEPFAGEERILINSPKVATYDLQPEMSSAELTEKLVAAIESGKY
                     DTIICNYPNGDMVGHTGVMEAAIKAVEALDNCIEQVTKAVESVGGQLLITADHGNAEQ
                     MRDPATGQEHTAHTNLPVPLIYVGEKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            16157..17440
                     /gene="envC"
                     /locus_tag="OPY25_002415"
     CDS             16157..17440
                     /gene="envC"
                     /locus_tag="OPY25_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HCS0928016.1"
                     /translation="MRGKAINTIQQAVKPRTFSVRPLFYASVLSAGVLLCAFSAHADD
                     RDQLKSIQADIAAKERDVRQQQQQRASLLAQLKTQEEAISAAARKLRETQSTLDQLNA
                     QIDEMNASIAKLEQQKASQERNLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAELKQTREQVATQKAELEEKQSQQQTLLYEQRAQQAKLEQARNERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDKQQEA
                     SRKGSTYKPTESERSLMSRTGGLGAPRGQAYWPVRGPILHRYGERLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGAQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            17444..18406
                     /locus_tag="OPY25_002416"
     CDS             17444..18406
                     /locus_tag="OPY25_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HCS0928017.1"
                     /translation="MPQFRRSILTLATLLAFAHPVFAGKLAIVIDDFGYRPHTENQVL
                     ALPPNISVAVLPNAPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKDTLRPDMSSDE
                     IERIIREAVNNVPYAVGLNNHMGSAMTSSLFGMQKVMQALEHYNLYFLDSMTIGNSQA
                     MRAASGTGVKVIKRKVFLDDTQNEADIRRQFNRTIELARRNGSAIAIGHPHPATVRVL
                     QQMVYRLPADITLVRPGSLLNEPQVDTSRPDLTPQKIDAPRNPFRGVKMCKPKKPLQP
                     VYATRFFSVIGESITQSSVIVWFQHQWQGWGKIAAPKNMSAKTD"
     gene            complement(18393..19427)
                     /locus_tag="OPY25_002417"
     CDS             complement(18393..19427)
                     /locus_tag="OPY25_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCS0928018.1"
                     /translation="MKNSKTKVSIIIPLYNAGADFNACMASLIAQTWSALEIIIVNDG
                     STDHSIEIAKHYAEHYPHVRLLHQANAGASVARNLGLQAATGDYVAFVDADDLVYPKM
                     YETLMTMALNDDLDVAQCNADWCVRKTGHAWQSIPTDRLRSTGVLSGPDWLRMALASR
                     RWTHVVWMGVYRRASITDNNITFVPGLHHQDILWSTEVMFNATRVRYTEQSLYKYFLH
                     DNSVSRLQRQGNKNLNYQRHYIKITRLLEKLNRDYARRIPIYPEFRQQITWEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYRRMMANVRSAKAAYQTLLWSFRLWQWRDKTLSHR
                     RMARKALNLS"
     gene            complement(19922..20947)
                     /gene="tdh"
                     /locus_tag="OPY25_002418"
     CDS             complement(19922..20947)
                     /gene="tdh"
                     /locus_tag="OPY25_002418"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCS0928019.1"
                     /translation="MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKE
                     SLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSVDDFQKGFDAMCSGQSG
                     KVILSWD"
     gene            complement(20957..22153)
                     /gene="kbl"
                     /locus_tag="OPY25_002419"
     CDS             complement(20957..22153)
                     /gene="kbl"
                     /locus_tag="OPY25_002419"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCS0928020.1"
                     /translation="MRGDFYKQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPELINAAKAGMDSHGFGMASVRFICGTQDSHKALEQKLASFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMVE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGAELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVDAFTRIGK
                     QLGVIA"
     gene            22356..23288
                     /gene="rfaD"
                     /locus_tag="OPY25_002420"
     CDS             22356..23288
                     /gene="rfaD"
                     /locus_tag="OPY25_002420"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HCS0928021.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     AVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKGSIEYIPFPDKLKGRYQAFT
                     QADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDA"
     gene            23291..24337
                     /gene="rfaF"
                     /locus_tag="OPY25_002421"
     CDS             23291..24337
                     /gene="rfaF"
                     /locus_tag="OPY25_002421"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001728214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HCS0928022.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLKARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRRLGHSLRERRYDRAWVLPNSFKSALIPFFANI
                     PHRTGWRGEMRYGLLNDARVLDKDAWPLMVERYVALAYDKGVMRTAKDLPQPLLWPQL
                     QVSEGEKSLMYSDFSLSSERPLIGFCPGAEFGPAKRWPHYHYAELAKQLINEGYQVVL
                     FGSAKDHEAGNEILAALNSEQQAWCRNLAGETQLEQAVILIAACKAIVTNDSGLMHVA
                     AALDRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDTAQGYHQSLIDITPQR
                     VLEELHSLLSEEGV"
     gene            24337..25290
                     /gene="rfaC"
                     /locus_tag="OPY25_002422"
     CDS             24337..25290
                     /gene="rfaC"
                     /locus_tag="OPY25_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HCS0928023.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWVVEEGFAQI
                     PSWHSAVDRVIPVAIRRWRKAWFSAPIKAERIAFHRAVCAYQYDAVIDAQGLVKSAAL
                     VTRLAHGIKHGMDWSTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQ
                     GDYAIAKHFLHCQQAVSDPYAVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWG
                     APHEEARAKRLAEGFDYVDVLPRMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TLYGPTDPGLIGGYGKNQMACCSPEQNLANLDATSVFGKIH"
     gene            25330..>25751
                     /locus_tag="OPY25_002423"
     CDS             25330..>25751
                     /locus_tag="OPY25_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase RfaL"
                     /protein_id="HCS0928024.1"
                     /translation="MLTTSLTLNKEKWKPIWNKALVFLFVATYFLDGITRYKHLIIIL
                     MVITAIYQVSRSPKSFPPLFKNSVFYSAAVLSLILVYSILISPDMKESFKEFENTVLE
                     GFLLYTLLIPVLLKDEIKETIAKIVLFSFLTSLGLRCLA"
BASE COUNT         6133 a         7005 c         6733 g         5880 t
ORIGIN      
        1 aacaccgctg atatcaccac caataccaac agcatcaatc agaacaccac tgatattgcc
       61 accaacacca ccagtatcaa caatctgagc aactccgtca ccacgctcac cgacgatgcc
      121 ctgttatggg atgctgactc tggcacattc agcgccagcc gtaacggaag cgccagcaaa
      181 atcaccaatc tggcggcggg taccctggcc gcggacagta cagacgccgt taacggctca
      241 caattgtatg aaaccaacca gaaggtggat caaaacacct ctgctatcgc agatattaat
      301 acgtccatca ccaatcttag ctctgacaac ctgagctgga atgaaacaac gaattcgttc
      361 tctgccagcc acggaagtag tacgacaaac aaaatcacca acgttgctgc cggagagctg
      421 tctgaagaaa gtaccgacgc ggttaacgga tcgcagttgt tcgaaaccaa tgaaaaagtg
      481 gatcagaaca cgaccgatat cgccgccaat accaccaaca tcactcagaa cagcaccgcg
      541 attgagaacc tgaatacttc tgtctccgac attaatacgt ccattaccgg cctcactgat
      601 aacgctctgt tatgggacga agacaccggc gctttcagcg caaaccacgg tggaagcacc
      661 agtaaaataa ccaatgtcgc cgccggggcg ctttctgagg acagtacaga cgcggtaaac
      721 ggatcacagt tgtatgaaac caaccagaag gtggatcaaa acacctctgc tatcgcggat
      781 atcaatacgt ccatcaccaa ccttggtacc gatgcactga gctgggatga cgaagagggt
      841 gcgttcagcg ccagccacgg taccagcggt accaataaga taactaatgt agcagcaggt
      901 gaaatcgcca gtgacagtac tgacgccatt aatggctctc agctctatga aactaacatg
      961 ctgatttctc agtataatga atctattagc caactagccg gcgataccag cgaaacctat
     1021 atcacggaaa atggtaccgg cgtgaaatac atccgtacga atgataacgg gcttgaaggc
     1081 caggatgcat acgcaacggg taacggcgca acggcagtag gttacgacgc cgtcgcctct
     1141 ggcgctggct gtctggctct tggccaaaac agcagcagca gcattgaggg cagtatcgct
     1201 ttgggcagtg gctccacctc taaccgcgct attacaaccg gtatacgaga aacgagcgca
     1261 acaagcgatg gcgtggtgat tggctacaat acaacagaca gagagttgct gggcgcgttg
     1321 tcattgggga cggatggaga aagctatcgt caaattacca acgttgctga cggctctgaa
     1381 gcgcaagatg cggtaacagt tcgtcagtta caaaatgcca ttggtgcggt cactactaca
     1441 ccgaccaagt actaccacgc aaactcaacg gaagaagatt cactggctgt cggaactgac
     1501 tcactggcaa tgggtgcgaa gactatcgtc aatgctgatg caggtattgg tattggtctg
     1561 aatacactgg tgatggctga tgccatcaac gggattgcta tcggttctaa cgcacgcgcc
     1621 aaccatgcaa acagtattgc aatgggtaat ggttctcaga ccactcgcgg tgcacagact
     1681 gactacaccg cctacaacat ggacacaccg cagaactctg tcggtgagtt ctctgtcggc
     1741 agtgaagacg gtcaacgtca gatcactaac gtcgcggcgg gttcggcaga taccgatgcc
     1801 gttaacgttg gtcaattgaa agtaacggac gcgcaggttt ccaggaatac ccagagcatt
     1861 actaacctga atactcaggt atcgaatctg gatacccgcg tcaccaatat cgaaaacggc
     1921 attggcgata tcgtcactac cggtagcacc aagtacttca agaccaacac cgatggcgca
     1981 gatgcaaatg cccagggtgc ggacagcgtc gcgattggct ctggctctat tgctgccgct
     2041 gaaaacagcg tggcgttagg cacaaattcc gtcgcagatg aagctaatac tgtgtctgtc
     2101 ggctcttcta ctcaacaacg ccgtattacc aacgttgccg caggggtgaa caacactgac
     2161 gcggttaatg tggcgcaact gaaagcctca gaagcaggct ccgtgcgtta tgaaaccaat
     2221 gcagatggct cggttaacta tagcgtgctc aacctgggag acgggagtgg cggcaccact
     2281 cggatcggca atgtttcagc ggcggtgaat gatacggatg cggttaacta tgcgcaattg
     2341 aaacgcagcg tcgaagaagc aaacacctat accgaccaga aaatggggga aatgaacagc
     2401 aaaatcaaag gcatagaaaa caagatgagc ggcggtatcg cttcagcgat ggcgatggcc
     2461 ggtctgccac aagcctacgc cccgggcgcc aacatgacct cgattgctgg cggtacgttt
     2521 aatggtgaaa gtgccgtcgc cattggtgtc tccatggtaa gtgaaagcgg gggctgggtg
     2581 tataaactgc aaggaaccag caacagccag ggcgattact ctgcagccat tggcgcgggc
     2641 ttccagtggt aatgaagtaa caacactccc gacatcaaag gcaatggcat aatgccattg
     2701 ccttttcact tccctttgtg gtcctctcct ctcaattggc cctaccaatt ttagccagtt
     2761 accacagcct actcacattt cactaaatta actctacaat atcgttgcca ataaataaca
     2821 tccggttaac tatttgttgt cattatccat acacaacaat attggcagga ccacttttac
     2881 acataatgtg acttcaacta gatgagcaaa gattcatccc attatgcgtg tggttctcag
     2941 gagacctgca atgaacctct ggcaacaaaa ctatgacccg gcgggtaata tctggctttc
     3001 cagcctgatc gcatcgctcc caatcctgtt cttctttttc gccctgatta aactcaagct
     3061 gaaaggctat gttgccgctt cgtggacggt ggttatcgcg ctcgccgtcg cgctgctgtt
     3121 ctataaaatg ccggtcgatc acgcgctggc atcggtcgtg tatggcttct tctacgggct
     3181 atggccgata gcctggataa tcatcgccgc ggtctttgtc tataaaattt cggtcaagac
     3241 cgggcagttt gacattattc gctcgtcaat tctgtcgatt acccccgacc agcgtctgca
     3301 aatgctgatt gtcggcttct gcttcggcgc gttccttgaa ggcgcggcgg gtttcggcgc
     3361 gccggtggcg ataaccgctg cgctgctggt gggcctgggc tttaaccctc tgtatgcggc
     3421 agggctgtgc ctgattgtaa acaccgcgcc ggtcgccttt ggcgcgatgg gtattccgat
     3481 tctggttgcc ggacaggtca cggacctgga cagctttgaa atcggtcaga tggtaggccg
     3541 ccagttgccg ttcctgacca ttatcgtgct gttctggatt atggcgatta tggacggctg
     3601 gcgcggcgtg aaagaaacct ggcctgcggt gatggtcgct ggcggctcgt ttgctatcgc
     3661 ccagtatctc agctccaact ttatcgggcc ggaactgccg gacatcatct cttcactggt
     3721 gtctctggtg tgtctgacgc tgttcctcaa acgctggcag ccggtacgca tcttccgctt
     3781 cggcgatatg ggcgcgtcgc aggtcgatca gacgctggcc cgcacccgtt atacgacagg
     3841 acaaattgtt cgcgcctggt cgccgttcct gttcctgacc gccacggtca cgctctggag
     3901 cataccgccg ttcaaagcgc tgtttgcccc cggcggcgcg ctgtatgact gggtaattaa
     3961 cgttccggta ccgtatctcg ataaactggt cgcccgtatg ccgccggtcg tacacgaagc
     4021 gaccgcttac gcggcggtgt ataaatttga ctggttctcc gccaccggca ctgcgatcct
     4081 gtttgccgcg ctgttgtcta ttgtctggct gaaaatgaaa ccctcagccg caatccagac
     4141 ctttggcagc acgctgaaag agctggcgtt gccgatttac tccatcggca tggtgctggc
     4201 gttcgcgttt atctcgaact attccgggct ttcctccacg ctggcgttag cgctggcgca
     4261 caccggcagc gccttcacgt tcttctcgcc gttcctcggc tggctgggcg tcttcctgac
     4321 cggctcggat acctcatcta acgcgctgtt tgcctctcta caggctaccg cggcgcagca
     4381 aatcggcgtc tctgatgtac tgatggtggc ggcgaacacc actggaggcg taaccgggaa
     4441 gatgatctcg ccgcagtcta tcgccatcgc ctgcgcggcg gtgggactgg tagggaaaga
     4501 gtccgatctg ttccgtttta ccgtcaaaca cagcctgatc ttcacctgta tggtgggcgt
     4561 gatcactacg cttcaggcct atgttttaac ctggatgatt ccgtgattgt gatgccaaaa
     4621 cgcctgtcag acgagattgc ctctcgcgtg cgggcgctga ttgaagaaca aaacctggaa
     4681 gcgggcatga aattgcccgc cgagcgccag ttggctctac agcttggcgt atcacgcaac
     4741 tctttacgcg aagcgctggc gaagctggtc agcgaaggcg tgctggtgag ccgtcgcggc
     4801 ggcgggacat ttgtccgctg gcagcacgaa acctggtctg aacagaatat cgtgcaaccg
     4861 ctgaaaatgc tgatggcgaa cgatccggac tacagtttcg acattctgga agcccgccac
     4921 gccattgaag ccagtacggc ctggcacgcc gccatgcgtg ccaccgccgc cgacaaagag
     4981 aaaatcagac tctgctttga tgcgacgctc agcgaagacc cggatctcgc ctcccaggcc
     5041 gacgtgcgct ttcatctggc gatcgcggaa gcctcgcata atgtggtgct gttgcaaacc
     5101 atgcgcggtt tcttcgacgt cctgcaatcc tccgtcaaac agagtcgcca gcgtatgtat
     5161 ctcgttccgc ccgtattctc aaagctgacg gaacaacacc aggcggtgtt ggacgccatt
     5221 ctggacggta acgccgaggg cgcgcgtaaa gcgatgatgg cgcacctcag ttttgtccac
     5281 accacgatta aacgatttga tgaagaccag gcccgccagg cgcgcattac ccgcctgccc
     5341 ggcgaccata atgagatgac cagggagaat aaatcatgat tatttcagca accagcgatt
     5401 atcgcgccgc agctcagcgc acgttgcctc ctttcctctt ccactacatc gacggcggcg
     5461 cgtatgcgga atataccctg cgccgaaatg tggaagacct gtcgcaagtc gctctgcgcc
     5521 agcgcgtgct gaaaaatatg tccgatttaa gcctggaaac gaccctgttt aacgaaacgt
     5581 tgtcgatgcc ggtggcatta gcgccggtag gtctgtgcgg catgtacgcc cgtcgcggcg
     5641 aagtacaggc cgccgccgcc gcagacgcaa agggcattcc gttcaccctt tccaccgtct
     5701 ccgtctgtcc gattgaagaa gtagccccca cgcttaaacg cccgatgtgg ttccagcttt
     5761 atgtactgcg tgaccggggc tttatgcgta atgcgctgga acgagcaaaa gcggcgggct
     5821 gctccacgct ggtctttacc gtggatatgc cgacgccggg cgcgcgctac cgtgacgccc
     5881 actccgggat gagcggccca aacgcggcca tgcgccgtta ctggcaggcg gtgatgcacc
     5941 ctaaatgggc gtgggatgtc ggcctgaacg gtcgcccgca tgatttaggc aatatttccg
     6001 cctatctggg taaaccgacc ggccttgagg actatatcgg ctggctggca aataacttcg
     6061 atccgtccat ctcctggaaa gatctggagt ggatacgcga attctgggac ggcccaatgg
     6121 tgatcaaagg gatcctcgat ccagaagatg cccgcgatgc ggtacgtttc ggcgctgacg
     6181 gtatcgtggt gtcgaatcac ggcggccgcc agctcgatgg cgtgctctct tccgcccgcg
     6241 ccctgcccgc cattgccgat gcggtgaaag gcgatatcgc cattctggcg gatagcggga
     6301 ttcgtaacgg gctggatgtc gtgcgtatga ttgcgctggg ggccgatacc gtactgctgg
     6361 gtcgggccta tctctacgcg ctggcgacgg caggaaaaac tggcgtcgct aacctactgg
     6421 acctgatcga gaaagagatg aaagtcgcca tgaccctgac cggcgcgaaa tccattagcg
     6481 aaatcagtgg cgattcactg gtgcaggaac tggggaaaag tttgcccgcc gcgctggcgc
     6541 caatgagcaa aggcgatgcc gcctgaacgt ctggcgcgtg agagcccggt aaatttctgc
     6601 tattctgccc cccgcattta agggggcatc atgcttaaca tcgtactctt cgaaccagaa
     6661 atcccgccga ataccggcaa catcattcgt ctttgcgcca ataccggctt tcgtctgcac
     6721 atcatcgaac cgatggggtt tgcctgggat gataagcgct tacgccgcgc agggttggac
     6781 tatcacgaat tcgccgcggt tcagcgccat cacgattatg ccgcctttgt cgccgccgaa
     6841 aatccacagc gcctgtttgc gttgacgaca aagggcacgc ccgcccatag cgccgtaagc
     6901 tatcaggatg gcgattattt gatgtttggc ccggaaacgc gcggcctgcc cgccagcatt
     6961 ctcgatgcgt tgcctaaaga gcagaagatt cgcattccga tgatgccgga tagccgtagc
     7021 atgaacctgt cgaatgcggt gtcggtggtg gtgtatgaag cgtggcgcca gttaggatac
     7081 cccggcgcgg tattgcggtc gtaatatatt caatgccgga tggcggctaa cgcctgatcc
     7141 ggcctggccg atcccgatgg catgttcccg tttatgcgga ctctcgctca atcaaatgaa
     7201 agccaatatc cacaatagct tctgcgcacg gtttctgttc aatacgatcg gccaacagcg
     7261 tagcggcgcg ctgaccaatg gcgcgtctgt caacgcttac ggtagtaatt gacggtcgat
     7321 tgctggcggc aaaatcaagg tcgccaaaac caataaccgc taaatcatgc gggatgcgca
     7381 aaccacggct ttccgcctcc atcatcgccc cctgtgccag ggtatcagaa ctgcaaacaa
     7441 tgacatcaaa cgtcccttcg tcaaaaagct ggcttaaacc gctacgcccc agcgaaagcg
     7501 atgccggaag ggggacatcc acctgcggta cggcatgaat agcgtggcgt tgaagaacac
     7561 tacataaccc ctgcttacgt tgcgcggctc ggcgatcggc ggtccacaac aagccgggac
     7621 gacgatagcc cttactcaga agatactccc ccgtcgcctg cccgactttt tcatgggaaa
     7681 aaccgaccag catatcaagc ggcgtgggcg ttaagtccca aatttccacc accggaatag
     7741 ccgcgttcag gatgaccttt ttcagttcta tcgtgtgatg gatcccggta agcaccacgc
     7801 catcggggcg gcgggaaagc agtgtcgcca ccaactccgc ttccgtttgt tcggtatatc
     7861 ccgccacgca cagcaatatg tgatatccgc gtcgggccag ttcatcgctc agtgactgga
     7921 tggtatcgac aaacatgttg ttgttaattt gcggcacgac gacagcgatt aatttactcc
     7981 gtcgcgacgc cagaccaccg gctaacgcgt tgggtatgta gcctgtgacg cgaaccgcct
     8041 gcatgacttt ctcaaccgtt ttggggcgaa ccagttgtgg cgaattcaat gcccggctga
     8101 ctgtcatcgg agacagcccg gcgctacgtg ctacatcttc cagcgtcggc gcacgaggtg
     8161 atttggttct cttcacgtct gatgcccctg caaagattgg ctgatttatc cgcgcattat
     8221 tcatcatgcc tgcggctatt gccagcttcg catcaggaaa ggccgtaaat acagtagctt
     8281 atcaagctca gtcattacaa aatgatagcg acatcatttt gtattatgca tttccccaga
     8341 tatttttgga tcgtgatcca ttttgcaata aatcctgctt tttatacgac atatgtgatc
     8401 aaatgttcaa atcaacatca actttctgga tcctgcgttc gcttaataat aaaaatgtta
     8461 gcgcaatcat tttgtgttta tcaggagaaa aaaaatggct ttaagcgcga attccgacgc
     8521 cgtaacgtat gcaaaagcgg cgaataccag aaccgcggca gaaaccggcg atcgtatcga
     8581 atgggtgaag ctatcactgg cttttctacc gctggcgacg ccagtgagtg acgcgaaggt
     8641 actgaccggt cgccagaaac ctttgaccga agtggcaatc atcattgccg aaatccgcag
     8701 tcgcgatggc tttgagggcg ttggttttag ctactccaaa cgtgctggcg gccagagtat
     8761 ttatgctcac gccaaagaga tagccgacaa tctactgggc gaagacccca atgatatcga
     8821 caaaatatac accaagctgc tgtgggccgg agcctcggtg gggcgtagcg ggatggcggt
     8881 acaggctatc tcccctatcg atatcgcctt atgggatatg aaggctaaac gtgccggtct
     8941 gccactggca aaactgttgg gcgcgcaccg cgactccgtt cagtgttaca acacctcagg
     9001 ggggttcttg catacaccgc tcgatcaagt gctgaaaaat gtggtgattt cccgcgaaaa
     9061 tggcattggc ggtattaagt tgaaagtcgg acaacccaac tgcgctgagg atattcgccg
     9121 cttaaccgca gtacgtgaag cgcttgggga tgagttcccg ttaatggttg acgctaacca
     9181 gcagtgggat cgcgaaacgg ctatccgcat ggggcgtaaa atggaacagt tcaatcttat
     9241 ctggattgaa gaaccattag atgcttacga catcgaaggc cacgcccagc ttgctgccgc
     9301 gctggatacg cctatcgcca ccggggaaat gctgaccagt ttccgggaac acgagcagtt
     9361 gattctgggc aatgccagcg atttcgttca gccagatgcg ccgcgtgtcg gcggtatctc
     9421 tccgttcctg aagattatgg atctggcggc gaaacacggg cgtaagctgg cgccgcactt
     9481 tgcgatggaa gtacacctgc acctttccgc agcgtatccc ctggagccgt ggctggaaca
     9541 tttcgagtgg ctgaacccat tattcaacga gcaacttgag ctgcgcgatg gccgcatgtg
     9601 gatttccgat cgtcatggtc tgggtttcac gctcagtgaa caagcgcgcc gctggacaca
     9661 attaacatgt gaatttggca aacgccctta acccgactgg cgggaatccg tcccgcctct
     9721 cttaccttac aggatgcatt ctgcccttat ctgaggagta gataatgaac acaataataa
     9781 agtgcacaaa agtgcgtcat accattctta tatttttatt tcttgctacc gtatttaatt
     9841 atgcggatcg cgcaactcta tccgtagttg ccccaataat gagtaaagaa ttaggttttg
     9901 atccggaagc gatgggcctg gccttctcct catttggtat tgcctatgtc attatgcaac
     9961 tacccggcgg ttggctatta gaccgctacg gttcacgact ggtttacggt tgcgcattga
    10021 ttggctggtc gttagtaacc atgtttcagg gaacgatcta tctgtatggc agcccattaa
    10081 ttgtactggt tactctacgt ctgctgatgg gcgcgattga agcgcctgcc tttccggcga
    10141 acagtcgttt aagcgtacaa tagtttccca ataatgaacg aggtttcgtt acttcagttt
    10201 atcaggctgc gcaatatatc tcgctgggca ttatcacccc gctaatgacg atcattctgc
    10261 ataatttaag ctggcatttt gtcttctatt atattggcgc cattggtgtg atgttcggta
    10321 tattctggtt aatgaaagtc aaagatccga tgcaccactc aaaagttaat caagcggaaa
    10381 ttgactatat tcgtagcggt ggtggcgagc cctctctggg ctgtaaaaag gagccgcaga
    10441 aaataacgtt cgcgcagatt aaaaccgtct gtgttaaccg gatgatgatc ggtgtttaca
    10501 tcgggcaatt ctgcgtcacc tctatcacct ggttcttcct gacctggttc ccgacctatc
    10561 tgtaccaggc gaaaggcatg tcgattctga aagtcggttt tgtggccagt attccagcca
    10621 ttgccggttt tattggcggc ctgctcggcg gcgtgttctc cgactggcta ctcaaacgcg
    10681 gctatagcct taccgtcgcg cggaaactgc ctgttatctg cggtatgttg ctctcttgcg
    10741 taattgtgat cgccaactac acctcttcag aatttgtggt cattgcggcg atgagtctgg
    10801 ccttttttgc caaagggttt ggtaacctgg gctggtgcgt actcagcgac acctcgccga
    10861 aggaagttct gggtattgct ggcggcgtat ttaacatgtg cggcaatatg gcaagcatcg
    10921 ttacgccact ggtcatcggc gtgattcttg ccaatactca gtcgttcgac tttgccattt
    10981 tatacgttgg ctcgatggga cttattggtc tcatttcata tctgtttatc gtcggcccgc
    11041 tggatcgcat cacgctgaca tcatccgcag cctgattgtc cacattgcga attcttcgct
    11101 ccgctgttcc gggattgcac tccatcggaa cagcgttttt tagttgtacc gcgcaattca
    11161 gatgccgtcg ccatactcaa acgtatggtg tagcccgttg aaatgctggt ccatatccat
    11221 cgacggctta tcgctgcccg gcttgccgac aatacgcgcc ggaacgcctg cggcggtagt
    11281 gtgcggcggg acaggctgta aaacgacgga gcctgcgcca attttcgcgc cgcgccccac
    11341 ctcgatattg ccgagaattt tcgcgcccgc gccaatcatc acgccttcgc ggattttagg
    11401 atggcgatcg ccgctcgttt tcccggtacc gcccagggtg acggattgca ggatcgacac
    11461 atcatcctca ataaccgccg tctcccccac cacaataccg gtggcatggt cgagcataat
    11521 cccgcggcca attttcgctg ccgggtgaat atccacctga aacgagaccg aaacctgatt
    11581 ttgcaggaag atagccagcg cgcggcgacc tttattccac aaccagtgac caatgcggta
    11641 ggcctgtagc gcatgaaagc ctttcagata taacagcggc gtggagtatt tatccaccgc
    11701 cggatcgcga gtgcgcacgg cctgaatatc gcaggctgcc gacgcgatca tttccgggtc
    11761 ggcggcatag gcttcttcaa ctacttcacg gatagcgata gcgggcatga tgggcgaagc
    11821 cagtttattt gccagcatat agctcagcgc actgcccaga ttttcatgct tgagtagcgt
    11881 ggcgtgataa aaactggcca acataggctc acagtcagct aaagcgcggg cttcagcttt
    11941 aatattcttc cagacgattt ccagttcttc acacggcatg gcttactcca gacgggcaga
    12001 aaacgaccaa cccgttctgt gcgggttggg tcgtttatgc aaacagttcc ttacggctag
    12061 tggcgactca gctcttcctt gcgggcgcga cctaataacg ttaatgctgc ctcgcgcgcg
    12121 ttttttccgc aatacaatac ttgataaatt tcctcggtta ttggcatttc aacaccaaaa
    12181 cggtgcgcca attcacgaac ttctttcgta ttgcgatagc cttcgaccac ctggccaatc
    12241 ttatcctgcg cgcctttaac gtccatgccc tggccaagca tcatgccaaa acgacggttg
    12301 cgcgactggt tgtcggtaca ggtcagcacc agatcgccta aacccgccat ccccataaag
    12361 gtggcgggat cggcaccaag cgctgcgcca agccgcgaca tttcggtcag tccacgcgtg
    12421 attagcgccg tgcgggcgtt cgcgccgaag ccgatgccgt cagacatccc cgcgccaatc
    12481 gcaatcacgt ttttcaccgc gccgccaagc tgcacgccga taaaatccgc attgatatag
    12541 acgcgaaaac tttttccgca gtgcaacagt tgctggagat cgtcggcaaa ggtctcatcg
    12601 gttgaggcta gcgagattgc cgtcggcaaa cccgccgcca gctctttagc gaacgtcgga
    12661 ccggaaatca ccgccagcgg gatttgatcg cctaacgcct cgcgagcgac atcctgcaac
    12721 aggcgccccg tttccgcttc caggcctttg gtcgcccata ccagacgcgc atccggacgc
    12781 atcagcggtt taatctgccg cagcacgtcg ctgaaaacat ggcttggcac caccaccaga
    12841 atgttacgac tggccgccag cgcggttgct aagtcgcttt ccaggtgtaa cgtatcggga
    12901 aaaggcacat cgggaaggaa cgcgacgttg cagcgatcgt gctccagggt cgcgatatgt
    12961 tttgggtcgt ggccccacag gacaacctgg tggccgtttc tcgccagagt gatggcgaga
    13021 gcggtgccgt acgagccggc accgatgact gtcattgacg cattactttg gttcatcagg
    13081 catcctgatg ttcttcagta ccttcgccag cctgctgctg caaatagttc atgaacagcg
    13141 catcaaagtt gaccggcgca aggttcagtt gcgggaacgt accgcgtgaa accagactgg
    13201 tgatgcactc gcgagcatac gggaacagaa tgttcgggca gtatgctccc aggcaatgcg
    13261 ccatctgagt gccttcaata ccgctgatgg agaaaatacc ggcctgctga acttcgcaca
    13321 ggaacgcggt ttcttccccc agggaagccg ttacggtaac acgcagcaca acttcataaa
    13381 cgtcatccgc cagttgggaa gatgccgtat caagatctag tttaacctct ggctgccaat
    13441 ctttctggaa aacatgcggt gcgtttggcg cttcgaaaga aacatccttg gtatagatac
    13501 gttggatctg gaaagccatt tcagtgttat tttgttctga catgtgtaaa accctttagt
    13561 gttgtcctta aatacttgag tacgccttaa cgcaacagcg gatccagtcc accacgcgca
    13621 tccagcgcat acaagtcgtc acaaccgcca atgtgctgtg catcaataaa aatttgcgga
    13681 accgtcgttc ggccactacg tttgatcatc tcttcacgct tcacggcgtc gccgtcaatc
    13741 gcaatttcct ggaaactcac gcccttgctg tttaacagcg cctttgcacg atggcaaaac
    13801 gggcaggttg ctttggtgta gatttcaata ttggccatga cttcgctcct gttttttacc
    13861 cgatggattt catgtcgacg caagggcaag tcattcccct tgcgtcatga aaacgacggg
    13921 taatcactta ccgcgcacca gaggcagatt ctcgccgctc cagcctgcta cgccttcttt
    13981 caacacaaag accttttcaa agccggcttt tgtcagcgcg ttagcggatt cctggcactg
    14041 cataccagaa ccgtcgacca cgataattgg cttgtctttg tgcttttcca gttcgccaac
    14101 attgttggct ttgatttcgc tcggcagcaa attggtcgcg ccagcgatat ggcctttacg
    14161 gaaatcgtca cgttgacgta aatccacaac aacggcgtcc tctttgttga taaggcgcgt
    14221 ggcttcgccg cgtgtaatca ccttaacttt tgaagtcaga cctttgaacg tggtaaataa
    14281 aaccgccacc agtaacgcaa tccaggcgat actcagtatg ggatgacggc caacaaattg
    14341 cataatttct tgcatggggg gtaacaactc ccgacgtagt gattaaaaaa ccaggaaagg
    14401 agtatacctg cgcagtggcg caaatacagc cagagcgtgc actggaatgc atttttgcgg
    14461 ggcgctacga aaaaaaatca cgctattact tgccttctca cgccagcgcg atccctttct
    14521 ttgatcttct gaggctattt tatcgattca gctgtagtaa aattacgcaa ttattttgtc
    14581 tattgagtat gaggttgtcg caatgtcggt ttctaaaaaa cctatggtac tggtgattct
    14641 ggatggctac ggctaccgtg aagaacagca ggataacgct atcttaaacg ccaaaacccc
    14701 ggtgatggat gctctgtggg caaaacgtcc gcataccctg atcgacgcat ccggtctgga
    14761 agtgggtctg cctgaccgcc agatgggcaa ctccgaagtg ggccacgtta acctgggcgc
    14821 aggccgcatc gtttatcagg acctgacgcg tctggacgtt gaaattaaag aacgtacttt
    14881 ctttgctaac ccagtcctga ccaatgcggt agaccaggcg aaaaacgccg gtaaagcggt
    14941 tcatattatg ggtctgctgt ccgcgggcgg cgtccacagc cacgaagatc acattatggc
    15001 gatggtggag ctggccgcag agcgcggcgc agaaaaaatc tatctgcacg ccttcctcga
    15061 cggtcgcgac acgccgccgc gcagcgctga agcctcgctg aaaaaattcg aagacaaatt
    15121 cgccgcgctg ggcaaaggtc gcgtggcgtc tatcgtcggt cgttactacg ctatggaccg
    15181 cgacaaccgt tgggatcgcg tggaaaaagc gtatgatctg atgaccctgg cccagggcga
    15241 attccaggcg gataccgctg tggctggcct gcaggccgct tacgctcgtg atgaaaacga
    15301 tgagtttgtc aaagcgaccg ttatccgcgc cgagggccag gctgatgcgg cgatggaaga
    15361 cggcgacacg ctgattttca tgaacttccg cgctgaccgc gcgcgcgaaa ttacccgcgc
    15421 tttcgttaat gctgatttcg acggctttgc gcgtaagaaa gtggttaatc tgaacttcgt
    15481 gatgctgacc gaatacgccg ccgatatcaa aactgccgtt gcctacccac cagcgtcgct
    15541 ggcgaatacc tttggcgaat ggatggcgaa aaacgacaaa actcagctgc gtatttccga
    15601 aacggaaaaa tatgcgcacg taaccttttt ctttaacggc ggcgtagaag aaccgtttgc
    15661 tggtgaagag cgtattctga tcaactcacc gaaagtggcc acttatgacc tgcaaccgga
    15721 aatgagctct gcagaattga ctgaaaaatt ggtcgcggcg atcgaaagcg gtaagtacga
    15781 caccatcatt tgtaactatc caaacggcga tatggtcggt cataccggcg tgatggaagc
    15841 cgccatcaaa gcggtggaag cgttggataa ctgcattgaa caggtaacaa aagcggttga
    15901 gtccgttggt ggacaactgt tgattaccgc ggaccacggc aacgcggagc agatgcgcga
    15961 tccggcgacc ggtcaggagc ataccgccca caccaacctg ccggtgccgc tgatttatgt
    16021 cggcgagaaa aacgtgaagg cggtcgaagg cggcaaactt tcagacattg cgcctaccat
    16081 gctgtcgctg atggggatgg aaatcccgca agagatgact ggtaagccgc tgttcatcgt
    16141 ggaataatcc ctccccatga ggggaaaggc gattaacacc attcaacagg ccgtgaaacc
    16201 aagaacgttt tcagtcaggc ctttgttcta cgccagcgta cttagcgctg gcgtattgtt
    16261 gtgcgccttt tccgcccacg cggatgaccg tgatcaactc aaatctattc aggccgatat
    16321 cgccgcgaaa gaacgcgacg tacgccagca gcagcaacag cgcgccagcc tcttggcaca
    16381 actgaaaacc caggaagagg ccatctcggc cgcagcgcgt aagctgcgcg aaacgcaaag
    16441 cactctggat cagttaaacg cgcaaattga tgagatgaac gcctcaattg ccaaactgga
    16501 gcagcaaaaa gccagccagg agcgtaatct cgctgcgcag ttggacgccg ctttccgcca
    16561 gggcgaacac accggcattc agcttattct tagcggagaa gagagccagc gtgggcaacg
    16621 cctgcaggcc tacttcggct atctgaacca ggcgcgccag gagactatcg ccgaactgaa
    16681 acagactcgc gaacaggtcg ccacgcaaaa agccgagctg gaagagaagc aaagccaaca
    16741 acaaacgttg ctgtatgaac agcgcgctca gcaggcgaag ctggaacagg cgcgtaatga
    16801 acgtaagaaa acgcttgccg gactggagtc gtctattcag caaggccagc aacagttaag
    16861 cgaactacgc gccaacgaat cacgcctacg caacagtatc gcgcgggcgg aagcggcggc
    16921 caaagcgcga gcggagcgtg aagcccgcga agcgcaggcg gtacgcgata agcagcagga
    16981 agcctcgcgt aaaggcagca cctataagcc gacggaaagc gagcgctcgc taatgtcccg
    17041 caccggcggt ctgggcgcgc ctcgcggtca ggcatactgg ccggtacgtg gcccgatatt
    17101 gcatcgttat ggcgaacggc tgcagggtga gctacgttgg aaggggatgg tgatcggcgc
    17161 gtcggaaggc accgaggtca aagccatcgc cgacggcagg gtgattctgg cggactggct
    17221 gcaaggctat ggcctggtgg tggtcgtgga gcatggtaaa ggtgatatga gcctttacgg
    17281 ctataaccag agcgcgctgg tcagcgtagg cgcgcaggtg cgcgccggac aacctatcgc
    17341 ccttgtgggc agtagcggcg gtcagggcag accttcgctt tatttcgaaa ttcgtcgcca
    17401 gggtcaggcc gtcaatccac agccgtggtt gggaagataa gttttgcctc agtttcgtcg
    17461 ctccattctc acgctggcca ctttgctggc atttgcacat cccgttttcg ctggcaagct
    17521 cgccatcgtg attgatgatt ttggctatcg cccgcacacg gaaaaccagg ttctggcgct
    17581 gccgccaaac atctccgtcg ctgtactgcc caacgcgccg cacgcgcgcg aaatggcgac
    17641 taaagcgcac aatagcgggc atgaggtgtt aatccatctg ccgatggcgc cgctaagcaa
    17701 acagccgctg gagaaggata cgctgcgacc agatatgagc agcgatgaga tcgagcgcat
    17761 tatccgcgag gcggtaaaca acgtgccgta tgccgttggg cttaataacc acatgggcag
    17821 cgcaatgact tccagcctgt tcggtatgca aaaagttatg caggcgctgg aacattacaa
    17881 tctctatttt ctcgacagca tgacgattgg caatagccag gcgatgcgcg cggcatccgg
    17941 tacgggtgtg aaagtgatca agcgcaaagt gttcctcgac gatacgcaaa acgaggcgga
    18001 tatccgtcgt cagtttaatc gcactatcga actggcccgt cgcaacggtt ccgctatcgc
    18061 gattggtcat ccgcatcccg caacggttcg cgtgctgcaa cagatggttt atcgcctgcc
    18121 ggcagatatc accctggtac gtccaggcag cctgctcaac gaaccgcagg tagatacgtc
    18181 tcgacctgat ttgacgccgc agaaaattga cgcgccgcgc aatccctttc gcggcgtgaa
    18241 gatgtgcaag ccgaaaaaac cgctgcaacc agtctacgct acgcgctttt tcagcgtcat
    18301 cggcgagagc attacgcaaa gttccgtgat tgtctggttt cagcaccagt ggcaaggctg
    18361 ggggaaaatc gccgcgccta aaaacatgag cgctaagaca gattgagcgc cttacgggcc
    18421 atacgacggt gcgacaaggt tttgtcgcgc cattgccaca gccggaagga ccagagcagc
    18481 gtctgataag ccgctttcgc gctgcggacg ttagccatca tccgtctata catgccagaa
    18541 gtaaaaattt cggcaatcat acgctggcgg gtcaaaatat caggttcttt acgcaccgca
    18601 tgacaaacgc gtaacgcttc ccaggtaatt tgctggcgaa actccgggta aatcggaata
    18661 cgccgggcat aatcacgatt gagcttttct aataaccgcg taattttaat ataatgccgc
    18721 tgataattaa gatttttatt gccttgtctt tgcaaacggc ttaccgaatt atcatgcagg
    18781 aaatatttat ataatgattg ttcggtataa cgtacgcgcg tggcattaaa cataacttcc
    18841 gtcgaccata atatgtcctg atgatgtagt ccgggaacga aagtaatatt gttatcggta
    18901 attgacgcac gtcgataaac gcccatccag acaacatgcg tccagcgtcg cgaggccaat
    18961 gccatacgca accaatccgg tccgcttaat accccggtgg aacgcagacg atcggtcgga
    19021 atagattgcc aggcgtgccc ggtttttcgg acgcaccagt ccgcattaca ctgcgcaacg
    19081 tccagatcat cgttaagcgc catagtcatc agcgtttcat acatcttcgg gtagaccagg
    19141 tcatccgcat cgacaaaggc gacataatct ccggtcgccg cttgcaaacc aagattacgg
    19201 gcgacagatg cgccagcatt ggcctgatga agcagtcgaa cgtgcgggta atgttccgcg
    19261 taatgttttg ctatctcaat ggaatgatct gtcgatccat cattcacaat aataatttcc
    19321 agcgccgacc acgtttgcgc gattaacgac gccatgcaag cattaaaatc cgctcccgca
    19381 ttatataacg ggataatgat actcactttg gttttactat ttttcataac gattaccaga
    19441 aaaaccttaa tttaccctgc ctttatactg tggctctatt aagaaactat taagccgcca
    19501 taattaattt ttacagtaaa aagcaagcac aaaactcaga gtagggcgtg acgttagcga
    19561 gtaaaataag attaaagcgc aattacgaat gcttgatgtc tatgacaatt ctttacagct
    19621 ttccagattt tccctaacaa aaaaggttgg cgaatgacac caacctttta cgatgaaacg
    19681 tatatcagac ccgataaata tcattgggtc tctataccct tcatacttca agttgcttat
    19741 gtgttggcta cggattactc ggcccatcta tgggcctcgc cctgacgggc cgtcgcacgc
    19801 gacgttcaaa tctgctcccg gcagatttgt cgttcacccc agtcacatag ttatctatgc
    19861 tcctggggac tcactccctt gccgccttta agcaactcga attattttgg gtatatacat
    19921 attaatccca gctcagaatg acttttcctg actggcctga acacatggcg tcaaaacctt
    19981 tctgaaaatc atcaacagag aaacgatggg tgataatcgg tgacagatcc agaccggact
    20041 ggatcagcgc cgccattttg taccacgttt cgaacatctc acgaccataa atacctttaa
    20101 tgaacaagcc tttaaagatg acttttgtcc agtcgataga catatctgat ggcggaatcc
    20161 ccagcatcgc aatacgaccg ccgtgattca tggtgtccag catggtacga aacgccggcg
    20221 gcgcgccgga catctccaga cccacatcaa acccttcggt cattcccagc tccgccatga
    20281 cgtcgttcag gctctctttc gcgacgttga ccgcgcgggt gacgcccatt ttgcgcgcca
    20341 gctccagacg gtattcattg acgtcagtaa tcaccacatg acgcgcgccg acatgtttcg
    20401 ccaccgcggc ggccattacg ccgattggcc ccgcccccga taccagtaca tcttcgccga
    20461 ccagatcgaa agacagcgcc gtatgcaccg cattaccaaa cgggtcgaaa atagaggcta
    20521 aatcatcaga aatgttatcc gggattttaa acgcattgaa tgccgggatg accaggtatt
    20581 ccgcgaagca gccgggacgg ttgacgccca cgccggtggt gttgcgacac aggtgagtac
    20641 gaccgccacg gcagttgcgg caatgaccgc aagtgatgtg accttcgccg gagacgcgat
    20701 cgccgatttt aaagcctttc acttcctgac cgatgccgac cacttcgccg acatattcat
    20761 gccccacgac catcggaacc gggatggttt tttgcgacca ttcatcccag ttatagatgt
    20821 gaacgtcagt gccgcagatg gctgttttac ggattttaat cagcaaatcg ttatggccga
    20881 cttccggttc cggaacgtcg gtcatccaga tgccctcttc cgctttcagt ttggataacg
    20941 ctttcatctt acatcctcag gcaatcacgc ccagttgttt accaatacgc gtgaacgcgt
    21001 ctaccgcacg cgtaatttgc tcaggcgtat gcgccgcaga catctgggta cgaatacgcg
    21061 cctgaccttt tggtacgacc ggatagaaga aaccggtaac gtaaatgccc tctttttgca
    21121 gttcgcgggc aaatttctgc gcgacaaccg catctcccag cattaccggg atgatggcgt
    21181 gatccgcgcc tgccagcgta aatcccgcgg cagacatctg ctcacggaac tgccgggcgt
    21241 tcgcccacaa gcgatcgcgc agttctgcgc ccgcttccac catctccaac actttaatag
    21301 aagccgccac gattgccggc gccagggagt tggagaacag atatgggcgg gaacgctgac
    21361 gcaaccactc aacgacctct ttacgcgccg cggtatagcc gccggatgcg ccgcctaacg
    21421 ctttgcccag cgtaccggta ataatatcta cgcggcccat tacgtcgcag tattcatggg
    21481 aaccgcgacc gttttcgccg acaaagccta ccgcgtgaga atcatcaacc atcaccagcg
    21541 catcgtattt atcggccaga tcacagacgc ctttcagatt ggcgatgacg ccatccattg
    21601 agaacacccc gtcggtggcg atcaggacat gacgcgcgcc ggcttcacgc gcctctttca
    21661 gccgagcttc cagctctacc atatcgttgt tggcatagcg atagcgcttc gctttacaca
    21721 aacgcacgcc gtcaatgata gacgcgtggt tcagcgcgtc ggaaataata gcgtcttccg
    21781 cgcccagcaa cgtctcaaac aagccgccgt tagcgtcgaa acaggaggaa tacagaatcg
    21841 catcttccat gccgaggaag cttgccagct tttgctccag cgctttgtgg ctgtcctggg
    21901 tgccgcagat aaaacgcacg gacgccatac cgaaaccgtg gctgtccatg cccgcttttg
    21961 cggcattaat cagctcaggg tgattcgcca gcccgagata gttattggcg caaaagttaa
    22021 taacgtggct tccatccgcc acggtgatat ccgcctgctg cgcagacgta ataatgcgct
    22081 cttctttaaa caatccttcc gcccgggcgg tttccagatc gttggttaac tgtttgtaaa
    22141 aatccccacg cattgcgatt ctccagactg ggcaaatttc agcacatatt acccaaagct
    22201 atacggtgat acgagatgac gcgtcatcac ttctttaaaa tgcagcataa atcacgcgta
    22261 tcctcacgag ttatcagtga atggatgaat agtgatatga taaaagcatt catgtctgag
    22321 acagtctctg acaccataat tcaaaggtta cagttatgat catcgttacc ggcggcgcgg
    22381 gctttatcgg cagcaatatc gttaaggccc tgaatgataa aggtatcacc gatattctgg
    22441 tggtggataa cctgaaagac ggcaccaagt ttgtaaacct ggtggatctg aacattgctg
    22501 actatatgga taaggaagat ttcctgatcc agattatgtc cggagaagag ctcggcgata
    22561 tcgaagctat tttccatgaa ggcgcctgct cttccaccac cgagtgggac ggcaagtata
    22621 tgatggataa taactatcaa tactccaaag agctgctgca ctattgtctt gagcgcgaaa
    22681 tcccgttcct ctacgcctct tctgccgcca cctatggcgg tcgcacgtct gatttcatcg
    22741 aatcgcgtga atacgaaaaa ccgcttaacg tttacggcta ttctaaattc ctgtttgatg
    22801 aatacgtgcg ccagatcctg ccagaagcga actcgcagat tgtcggtttc cgctatttca
    22861 acgtctatgg accacgtgaa ggccataaag gcagcatggc aagcgtggca tttcatctga
    22921 atacacagtt aaacaacggc gaaagtccga aactgtttga aggcagcgaa aacttcaagc
    22981 gcgacttcgt ttacgtgggc gatgtggccg ccgttaacct gtggttcctg gaaagcggca
    23041 agtccggcat ctttaacctg ggcacaggcc gcgcggaatc tttccaggcc gtcgccgacg
    23101 cgacgctggc ataccataaa aaaggcagca ttgaatacat tccgttcccg gataagctga
    23161 aaggtcgcta tcaggcgttt acgcaggcgg atttaaccaa tctgcgcaac gcgggctacg
    23221 acaaaccctt taagaccgtc gccgaaggcg tcacggagta tatggcctgg ctgaaccgcg
    23281 acgcgtaagt atgaaaattt tggtcattgg cccgtcctgg gtgggcgaca tgatgatgtc
    23341 gcaaagtctc tatcgcacgc ttaaagcgcg ctatccccag gcgataatcg acgtgatggc
    23401 gccagcctgg tgccgtccgt tgttatcgcg tatgccggaa gttaacgagg cgatacccat
    23461 gccgctgggc cacggcgcgc tggaaatcgg cgagcgccgc agattgggcc atagcctgcg
    23521 agagaggcgc tacgatcgcg cctgggtgct gccaaattcg tttaaatcgg cgctgattcc
    23581 tttctttgcc aatatcccgc accgtaccgg ctggcgtggc gaaatgcgct atggcctgct
    23641 gaacgatgcg cgcgtccttg ataaagacgc ctggccgctg atggtggagc gctacgtggc
    23701 gctggcctat gacaagggcg tgatgcgcac ggcgaaagat ctgccgcagc cgctgctctg
    23761 gccacagctc caggttagcg agggtgaaaa atcgctgatg tacagcgatt tttcgctatc
    23821 ttctgaacgt cctctaatcg gcttttgccc cggagcagaa tttggcccgg caaaacgttg
    23881 gccgcactat cactacgccg aactggcaaa gcagctcatt aacgaagggt atcaggtcgt
    23941 gctgtttggc tcggcaaaag accatgaagc cggaaatgag atcctggcgg cgctgaatag
    24001 cgagcaacag gcatggtgtc gcaacctggc aggggaaacc cagctggaac aggccgtcat
    24061 tctgatagcc gcctgtaaag ccatcgtcac taacgattcc gggctgatgc acgtcgcggc
    24121 ggcgctcgac cgcccgctgg tcgcgttgta tggcccaagt agcccggatt tcacgccgcc
    24181 gctgtctcat aaggcccggg tgattcgtct cattacgggt taccacaaag tgcgtaaagg
    24241 cgatacggcg caaggctatc accagagcct gatcgatatc acgccgcagc gggttctgga
    24301 agagcttcat tcgctgttgt cggaagaggg cgtttaatgc gagttttgat cgttaaaaca
    24361 tcatcgatgg gcgacgtatt acataccctg cctgcgctta ccgacgcgca acaggcgatt
    24421 ccggggattc aatttgattg ggttgtcgaa gaagggtttg cacaaattcc gtcctggcac
    24481 agtgctgtcg atcgcgtgat tcccgtcgct attcgccgtt ggcgcaaggc ctggttttcc
    24541 gcgcccatta aagcggaacg catagccttt catcgggcgg tatgcgcata ccaatacgac
    24601 gctgtgattg atgcgcaggg gctggtaaaa agcgcggcgc tggtgacgcg tctggcgcat
    24661 gggataaagc acggtatgga ctggagtacc gcccgcgaac cgctggccag cctgttttat
    24721 aaccgtaaac accatatcgc aaagcaacaa catgcggttg aacggacgcg cgagctgttc
    24781 gccaaaagcc tgggatacga taaaccgcag tcgcagggcg attatgccat cgcaaaacat
    24841 tttctgcatt gccagcaggc ggttagcgat ccgtatgcgg tgtttttaca tgccacgacc
    24901 cgcgatgata aacactggcc ggaagcaaac tggcgcgagc ttatcggcct ggtgggcaac
    24961 accggattac ggataaaact tccctggggc gcgcctcatg aggaggctcg tgctaaacga
    25021 ctggccgaag gctttgacta tgtggatgtg ttaccgcgca tgagcctgga ggaggtcgct
    25081 agagtgctgg ctggcgcaaa atttgtcgta tcggttgata ccggcctgag ccatctcacc
    25141 gccgcgctcg acagaccgaa tattacgcta tatggcccaa cggaccctgg gttaattgga
    25201 ggttatggga agaaccaaat ggcatgctgc tcaccagaac aaaacctggc gaatttagat
    25261 gccacaagcg tatttggaaa gattcattaa agagactctg tctcatccca aacctattgt
    25321 ggagaaaaga tgctaaccac atcattaacg ttaaataaag agaaatggaa gccgatctgg
    25381 aataaagcgc tggtttttct ttttgttgcc acgtattttc tggatggtat tacgcgttat
    25441 aaacatttga taatcatact tatggttatc accgcgattt atcaggtctc acgctcaccg
    25501 aaaagtttcc cccctctttt caaaaatagc gtattttata gcgcagcagt attatcatta
    25561 atccttgttt attccatact catatcgcca gatatgaaag aaagtttcaa agaatttgaa
    25621 aatacggtac tggagggttt cttattatat actttattaa ttcccgtact attaaaagat
    25681 gaaataaaag aaacgattgc gaaaatagta cttttctcct ttttaacaag tttaggactt
    25741 cgctgccttg c
//
LOCUS       DAJVKX010000057        24518 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000057 DAJVKX010000000
VERSION     DAJVKX010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24518
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.057"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            77..2353
                     /gene="phsA"
                     /locus_tag="OPY25_002424"
     CDS             77..2353
                     /gene="phsA"
                     /locus_tag="OPY25_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase PhsA"
                     /protein_id="HCS0928025.1"
                     /translation="MSISRRSFLQGVGIGCSACALGAFPPGALARNPIAGINGKTTLT
                     PSLCEMCSFRCPIQAQVVNNKTVFIQGNPSAPQQGTRICARGGSGVSLVNDPQRIVKP
                     MKRTGPRGDGEWQVISWQQAYQEIAAKMNAIKAQHGPESVAFSSKSGSLSSHLFHLAT
                     AFGSPNTFTHASTCPAGKAIAAKVMMGGDLAMDIANTRYLVSFGHNLYEGIEVADTHE
                     LMTAQEKGAKMVSFDPRLSIFSSKADEWHAIRPGGDLAVLLAMCHVMIDEQLYDASFV
                     ERYTSGFEQLAQAVKETTSEWAAAQADVPADVIVRVTRELAACAPHAIVSPGHRATFS
                     QEEIDMRRMIFTLNVLLGNIEREGGLYQKKNASVYNKLAGEKVAPTLAKLNIKNMPKP
                     TAQRIDLVAPQFKYIAAGGGVVQSIIDAALTQKPYPIKAWIMSRHNPFQTVTCRSDLV
                     KTVEQLDLVVSCDVYLSESAAYADYLLPECTYLERDEEVSDMSGLHPAYALRQQVVEP
                     IGEARPSWQIWKELGEQLGLGQYYPWQDMQTRQLYQLNGDHALAKELRQKGYLEWGVP
                     LLLREPESVRQFTARYPGAIATDSDNTYGEQLRFKSPSGKIELYSATLEELLPGYGVP
                     RVRDFALKKENELYFIQGKVAVHTNGATQYVPLLSELMWDNAVWVHPQTAQEKGIKTG
                     DEIWLENATGKEKGKALVTPGIRPDTLFVYMGFGAKAGAKTAATTHGIHSGNLLPHVT
                     SPVSGTVVHTAGVTLSRA"
     gene            2368..2946
                     /gene="phsB"
                     /locus_tag="OPY25_002425"
     CDS             2368..2946
                     /gene="phsB"
                     /locus_tag="OPY25_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase electron transport protein
                     PhsB"
                     /protein_id="HCS0928026.1"
                     /translation="MNHLTNQYVMLHDEKRCIGCQACTVACKVLNDVPEGFSRVQVQI
                     RAPEQASNALTHFQFVRVSCQHCENAPCVSVCPTGASYRDENGIVQVDKSRCIGCDYC
                     VAACPFHVRYLNPQTGVADKCNFCADTRLAAGQSPACVSVCPTDALKFGRLDESEIQR
                     WVGQKEVYRQQEARSGAVSLYRRKEVHQEGKA"
     gene            2943..3707
                     /locus_tag="OPY25_002426"
     CDS             2943..3707
                     /locus_tag="OPY25_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HCS0928027.1"
                     /translation="MNTIWGAELHYAPDYWPLWLIYAGVVVLLMLVGLVIHALLRRML
                     APKTAGGEEHRDYLYSLAIRRWHWGNALLFVLLLLSGLFGHFSLGPVALMVQVHTWCG
                     FALLAFWVGFVLINLTTGNGRHYRVNFSGLVTRCIRQTRFYLFGIMKGEAHPFAATEQ
                     NKFNPLQQLAYLAIMYALVPLLIITGLLCLYPQVAGLGPVMLVLHMALAIIGLLFICA
                     HLYLCTLGDTPGQIFRSMVDGYHRHRTAPRGDKSAV"
     gene            3831..5003
                     /gene="dacD"
                     /locus_tag="OPY25_002427"
                     /pseudo
     CDS             3831..5003
                     /gene="dacD"
                     /locus_tag="OPY25_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
     gene            5154..5621
                     /gene="sbmC"
                     /locus_tag="OPY25_002428"
     CDS             5154..5621
                     /gene="sbmC"
                     /locus_tag="OPY25_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HCS0928028.1"
                     /translation="MDYEIRQEQKRKIAGFHMVGPWEHTVKQGFEQLMTWVDRQRIVP
                     VEWIAVYYDNPDVVPAEKLRCDTVVSVAENFILPDNSEGVIVTAIEGGEYATAVARVE
                     DRDFAKPWERFFDVLEQDSAYQIASAPCFETYLNNGMEDGYWDIEMYIPVQRK"
     gene            5740..6798
                     /locus_tag="OPY25_002429"
     CDS             5740..6798
                     /locus_tag="OPY25_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCS0928029.1"
                     /translation="MRADKSLSPFEIRLYRHYRIVHGIRIALAFILTFLLVRLFSIPE
                     GTWPLITLVVIMGPISFWGNVVPRAFERIGGTILGAALGLVALRLELFSLPLMLVWCA
                     IAMFLCGWLALGKKPYQALLIGITLAVVVGAPAGDMNTALWRGGDVILGALLAMLFTG
                     IWPQRAFLHWRIQLAHCVTAYNRVYQAALSPNLLERPRLDKYLQRLLNDVVKMRGLIT
                     PASKETRIQKSIFEAIQTINRNLVCMLELQINAHWATRASHFVMLNTHTLRETQQMTQ
                     QTLLTIAHALFEGNPQPVLANTGKLNDIAAELRQLMNEQQGDAVAETPIHGYVWLSME
                     TARQLELLSHLICRALRK"
     gene            7043..7378
                     /locus_tag="OPY25_002430"
     CDS             7043..7378
                     /locus_tag="OPY25_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HCS0928030.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDIEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAEISKERRDISKKLKAMGE
                     MKHADVKAE"
     gene            complement(7412..8278)
                     /gene="pduX"
                     /locus_tag="OPY25_002431"
     CDS             complement(7412..8278)
                     /gene="pduX"
                     /locus_tag="OPY25_002431"
                     /EC_number="2.7.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine kinase PduX"
                     /protein_id="HCS0928031.1"
                     /translation="MAVAQCPASCGELIQGWILGSEKLVSCPVDWYSTVAVTAAPPLV
                     NERPLSRAMVERVLAHWQYPAHWSNEIRVDVRSSIPVAKGMASSTADIAATAVATAHH
                     LGHSLDETTLAQLCVSIEPTDSTVFHQLTLFDHNNAATQIACEPPPPIDLLVLESPVT
                     LRTQDYHRLPRQQKLIASSPTLQQAWNLVQEACITQNPLRLGEAATLSAIASQTLLPK
                     PGFTALLSLVEECDLYGLNVAHSGSVVGLMLDRKRHDIARLKGKLAEKKLTRHWPKQH
                     LLKMVTGGVKLQ"
     gene            complement(8372..9586)
                     /gene="pduW"
                     /locus_tag="OPY25_002432"
     CDS             complement(8372..9586)
                     /gene="pduW"
                     /locus_tag="OPY25_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization propionate kinase PduW"
                     /protein_id="HCS0928032.1"
                     /translation="MSYKIMAINAGSSSLKFQLLEMPQGDMLCQGLIERIGMADAQVT
                     IKTHSQKWQETVPVADHRDAVTLLLEKLLGYQIINSLRDIDGVGHRVAHGGEFFKDST
                     LVTDETLAQIERLAELAPLHNPVNALGIHVFRQLLPDAPSVAVFDTAFHQTLDEPAYI
                     YPLPWHYYAELGIRRYGFHGTSHKYVSGVLAEKLGVPLSALRVICCHLGNGSSVCAIK
                     NGRSVNTSMGFTPQSGVMMGTRSGDIDPSILPWIAQRECKTPQQLNQLLNNESGLLGV
                     SGVSSDYRDVEQAANTGNRQAKLALTLFAERIRATIGGYIMQMGGLDALVFTGGIGEN
                     SARARSAVCHNLQFLGLAVDEEKNQRNATFIQTENALVKVAVINTNEELMIAQDVMRI
                     ALPATEGLCVPA"
     gene            complement(9571..10023)
                     /gene="pduV"
                     /locus_tag="OPY25_002433"
     CDS             complement(9571..10023)
                     /gene="pduV"
                     /locus_tag="OPY25_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization protein PduV"
                     /protein_id="HCS0928033.1"
                     /translation="MKRLMFIGPSQCGKTSLTQSLRGEALHYKKTQAIEWSPMAIDTP
                     GEYLENRCLYSALLTSACEADVIALVLNADAQWSPFSPGFTVPMNRPTIGLVTKADLA
                     DPQRISLVAQWLTQAGARQIFITSALNNSGLDAVLDFLNSKEPLCLTK"
     gene            complement(10028..10378)
                     /gene="pduU"
                     /locus_tag="OPY25_002434"
     CDS             complement(10028..10378)
                     /gene="pduU"
                     /locus_tag="OPY25_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduU"
                     /protein_id="HCS0928034.1"
                     /translation="MERQPTTDRMIQEYVPGKQVTLAHLIANPGKDLFKKLGLQDAVS
                     AIGILTITPSEASIIACDIATKSGAVEIGFLDRFTGAVVLTGDVSAVEYALKQVTRTL
                     GEMMQFTTCSITRT"
     gene            complement(10378..10932)
                     /gene="pduT"
                     /locus_tag="OPY25_002435"
     CDS             complement(10378..10932)
                     /gene="pduT"
                     /locus_tag="OPY25_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduT"
                     /protein_id="HCS0928035.1"
                     /translation="MSQAIGILELTSIAKGMELGDAMLKSANVDLLVSKTICPSKFLL
                     MLGGDIGAIQQAIETGTSQAGEMLVDSLVLANIHPSVLPAISGLNSVDKRQAVGIVET
                     WSVAACISAADRAVKGSNVTLVRVHMAFGIGGKCYMVVAGDVSDVNNAVTVASESAGE
                     KGLLVYRSVIPRSHEAMWRQMVEG"
     gene            complement(10935..12263)
                     /gene="pduS"
                     /locus_tag="OPY25_002436"
     CDS             complement(10935..12263)
                     /gene="pduS"
                     /locus_tag="OPY25_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin reductase PduS"
                     /protein_id="HCS0928036.1"
                     /translation="MSLSADEIRERVRAAGVVGAGGAGFPAHVKLQAQVEIFLVNAAE
                     CEPMLKVDQQLMWQQAARLVRGVQYAMTATGAREGVIALKEKYRRAIDALSPLLPAGI
                     RLHILPDVYPAGDEVLTIWMATGRRVAPAALPASVGVVVNNVQTVLNIARAVEQQFPV
                     TRRTLTVNGAVARPLTVTVPVGMSLHEVLALAGGATVDNPGFINGGPMMGGLITSLDN
                     PVTKTTGGLLVLPKSHPLIQRRMQDERTVLSVARTVCEQCRLCTDLCPRHLIGHELSP
                     HLLVRAVNFHQAATPQLLLSALTCSECNVCESVACPVGISPMRINRMLKRELRAQNQR
                     YEGPLNPADEMAKYRLVPVKRLIAKLGLSPWYQEAPLVEEEPSVEKVTLQLRQHIGAS
                     AVPTVAVGERVTRGQCVADVPPGALGASIHASIDGIVSAISEQAITVVRG"
     gene            complement(12287..13399)
                     /gene="pduQ"
                     /locus_tag="OPY25_002437"
     CDS             complement(12287..13399)
                     /gene="pduQ"
                     /locus_tag="OPY25_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-propanol dehydrogenase PduQ"
                     /protein_id="HCS0928037.1"
                     /translation="MNTFSLQTRLYSGQGSLAVLKRFTNKHIWIICDGFLARSPLLDT
                     LCNALPADNRISVFSEITPDPTIHTVVQGIAQMQALQPQVVIGFGGGSAMDAAKAIVW
                     FSQQSGINIETCVAIPTTSGTGSEVTSACVISDPDKGIKYPLFNNALYPDMAILDPEL
                     VVSVPPQITANTGMDVLTHALEAWVSPHASDFTDALAEKAAKLVFQYLPTAVEKGDCV
                     ATRGKMHNASTLAGMAFSQAGLGLNHAIAHQLGGQFHLPHGLANALLLTTVIRFNAGV
                     PRAAKRYARLAKACGFCPAEANDVTAINALIQQIELLKQRCALPSLAVALKEGRSDFS
                     ARIPAMVQAALADVTLRTNPRPASAEEIRELLEELL"
     gene            complement(13411..14805)
                     /gene="pduP"
                     /locus_tag="OPY25_002438"
     CDS             complement(13411..14805)
                     /gene="pduP"
                     /locus_tag="OPY25_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating propionaldehyde dehydrogenase
                     PduP"
                     /protein_id="HCS0928038.1"
                     /translation="MNTSELETLIRTILSEQLTTPAQTPAQPQGKGIFQSVSEAIDAA
                     HQAFLRYQQCPLKTRSAIISAMRQELTPLLAALAEESANETGMGNKEDKFLKNKAALD
                     NTPGVEDLTTTALTGDGGMVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIY
                     FSPHPGAKKVSLKLISLIEEIAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAIT
                     GGPGIVAMGMKSGKKVIGAGAGNPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKS
                     LIVVESVAERLVQQMQTFGALLLSPADTDKLRAVCLPEGQANKKLVGKSPSAMLEAAG
                     IAVPAKAPRLLIALVNADDPWVTREQLMPMLPVVKVNDFDSALALALKVEEGLHHTAI
                     MHSQNVSRLNLAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFA
                     RSRRCVLTNGFSIR"
     gene            complement(14802..15812)
                     /gene="pduO"
                     /locus_tag="OPY25_002439"
     CDS             complement(14802..15812)
                     /gene="pduO"
                     /locus_tag="OPY25_002439"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-domain cob(I)yrinic acid a,c-diamide
                     adenosyltransferase PduO"
                     /protein_id="HCS0928039.1"
                     /translation="MAIYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLC
                     ACAAADENHRTLLEAIQQQLFWFSAELASDSEQPSPKQRYISSEEISALEAAIDRAMA
                     RVEPLHSFILPGRCEAASRLHFARTLARRAERRLVELATEVNVRQVLMRYINRLSDCL
                     YALARAEDSDAHQANIIREVSKRYLAASQPTRSKETTPVALSFHDLHQLTRAAVERAQ
                     QLQVPVVVSIVDAHGTETVTWRMPDALLVSSELAPKKAWTAVAMKTATHELSDVVQPG
                     AALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMDIAQTAIAAINVGT
                     HQ"
     gene            complement(15822..16096)
                     /gene="pduN"
                     /locus_tag="OPY25_002440"
                     /pseudo
     CDS             complement(15822..16096)
                     /gene="pduN"
                     /locus_tag="OPY25_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduN"
     gene            complement(16100..16591)
                     /gene="pduM"
                     /locus_tag="OPY25_002441"
     CDS             complement(16100..16591)
                     /gene="pduM"
                     /locus_tag="OPY25_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduM"
                     /protein_id="HCS0928040.1"
                     /translation="MNGETLQRIVEEIVSRLQRRALSTATLSVAQLRDADCPALFCQH
                     ASLRILLVDLPLLGQLADAETDDAAARKIHDALAFGIRVQLSLHSQLLPVIPVKKLAR
                     LPLVFTDEHGLPLVLHAGSVLGYRDVALLSRGRVVVHRKCIVTAMARDAANARNIQLI
                     KQE"
     gene            complement(16588..17220)
                     /locus_tag="OPY25_002442"
     CDS             complement(16588..17220)
                     /locus_tag="OPY25_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HCS0928041.1"
                     /translation="MDKELLQSTVRKVLDEMRQRPIPLGVSNRHIHLSAQDYERLFPG
                     HPISEKKALLQPGQYATEQTVTLVGPKGQLKNVRLLGPLRSVSQVEISRTDARTLGIA
                     APLRMSGNLKGTPGIRLVSPFGELELPSGVIVAQRHIHMSPLDALILKVSHGDRVSVA
                     IEGDERGLIFNNVAIRVSPDMRLEMHIDTDEANAAGADNPQAFARLVGPR"
     gene            complement(17220..17702)
                     /gene="pduK"
                     /locus_tag="OPY25_002443"
     CDS             complement(17220..17702)
                     /gene="pduK"
                     /locus_tag="OPY25_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460991.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduK"
                     /protein_id="HCS0928042.1"
                     /translation="MANKEHRVKQSLGLLEVCGLALAISCADIMAKSASITLLALEKT
                     NGSGWMVIKIAGDVASVQAAITTGAQFAEQRNGLVAHKVIARPGEGILLAETPSPSVI
                     EPEPEASEIADVVSEAPAEEAPQESELVSCNLCLDPKCPRQKGEPRTLCIHSGKRGEA
                     "
     gene            complement(17706..17981)
                     /gene="pduJ"
                     /locus_tag="OPY25_002444"
     CDS             complement(17706..17981)
                     /gene="pduJ"
                     /locus_tag="OPY25_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduJ"
                     /protein_id="HCS0928043.1"
                     /translation="MNNALGLVETKGLVGAIEAADAMVKSANVQLVGYEKIGSGLVTV
                     MVRGDVGAVKAAVDAGSAAASVVGEVKSCHVIPRPHSDVEAILPKSA"
     gene            complement(18001..18351)
                     /gene="pduH"
                     /locus_tag="OPY25_002445"
     CDS             complement(18001..18351)
                     /gene="pduH"
                     /locus_tag="OPY25_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase reactivase beta subunit
                     PduH"
                     /protein_id="HCS0928044.1"
                     /translation="MDSNHSAPAIVITVINDCASLWHEVLLGIEEEGIPFLLQHHPAG
                     DVVDSAWQAARSSPLLVGIACDRHSLVVHYKNLPASAPLFTLMHHQDSQAQRNTGNNA
                     ARLVKGIPFRDLNS"
     gene            complement(18341..20173)
                     /gene="pduG"
                     /locus_tag="OPY25_002446"
     CDS             complement(18341..20173)
                     /gene="pduG"
                     /locus_tag="OPY25_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase reactivase alpha subunit
                     PduG"
                     /protein_id="HCS0928045.1"
                     /translation="MRYIAGIDIGNSSTEVALARQDETGALTITHSALAENTGIKGTL
                     RNVFGIQEALALVAKRAGINVSDISLIRINEATPVIGDVAMETITETIITESTMIGHN
                     PKTPGGAGLGVGITITPEELLTRPADSSYILVVSSAFDFADIANVINASMRAGYQITG
                     VILQRDDGVLVSNRLEKSLPIVDEVLYIDCIPLGMLAAIEVAVPGKVIETLSNPYGIA
                     TVFNLNADETKNIVPMARALIGNRSAVVVKTPSGDVKARAIPAGNLELQAQGRTVRVD
                     VAAGAEAIMKAVDGYGKLDNVNGEAGTNIGGMLEHVRQTMAELTNKPSSEIFIQDLLA
                     VDTSVPVSVTGGLAGEFSLEQAVGIASMVKSDRLQMAMIAREIEQKLNIDVQIGGAEA
                     EAAILGALTTPGTTRPLAILDLGAGSTDASIINPKGEIIATHLAGAGDMVTMIIAREL
                     GLEDRYLAEEIKKYPLAKVESLFHLRHEDGSVQFFPTPLPPAVFARVCVVKPDELVPL
                     PGDLALEKVRAIRRSAKERVFVTNALRALRQVSPTGNIRDIPFVVLVGGSSLDFEVPQ
                     LVTDALAHYRLVAGRGNIRGSEGPRNAVATGLILSWHKEFAYGQ"
     gene            complement(20380..20901)
                     /gene="pduE"
                     /locus_tag="OPY25_002447"
     CDS             complement(20380..20901)
                     /gene="pduE"
                     /locus_tag="OPY25_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase small subunit PduE"
                     /protein_id="HCS0928046.1"
                     /translation="MNTDAIESMVRDVLSRMNSLQGDAPAAAPAAGGTSRSAKVSDYP
                     LANKHPEWVKTATNKTLDDFTLENVLSNKVTAQDMRITPKTLRLQASIAKDAGRDRLA
                     MNFERAAELTAVPDDRILEIYNALRPYRSTKEELLAIADDLENRYQAKICAAFVREAA
                     GLYVERKKLKGDD"
     gene            complement(20916..21590)
                     /gene="pduD"
                     /locus_tag="OPY25_002448"
     CDS             complement(20916..21590)
                     /gene="pduD"
                     /locus_tag="OPY25_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase medium subunit PduD"
                     /protein_id="HCS0928047.1"
                     /translation="MEINEKLLRQIIEDVLRDMKGSDKPVSFNTPAASTAPQTAAPAG
                     DGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGLPHKSILREVIAGIEEEGIRA
                     RVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKDTTVIHQQGLPPLSNLELFPQAPLL
                     TLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQ
                     ELRVTL"
     gene            complement(21601..23265)
                     /gene="pduC"
                     /locus_tag="OPY25_002449"
     CDS             complement(21601..23265)
                     /gene="pduC"
                     /locus_tag="OPY25_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase large subunit PduC"
                     /protein_id="HCS0928048.1"
                     /translation="MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIV
                     NGAVTELDGKPVSEFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIV
                     PLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAE
                     GAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTC
                     YAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSM
                     LYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECSSSN
                     DQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQR
                     DLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPE
                     RNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAII
                     VGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID"
     gene            complement(23284..24096)
                     /gene="pduB"
                     /locus_tag="OPY25_002450"
     CDS             complement(23284..24096)
                     /gene="pduB"
                     /locus_tag="OPY25_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduB"
                     /protein_id="HCS0928049.1"
                     /translation="MSSNELVEQIMAQVIARVATPEQQAIPGQPQPIRETAMAEKSCS
                     LTEFVGTAIGDTLGLVIANVDTALLDAMKLEKRYRSIGILGARTGAGPHIMAADEAVK
                     ATNTEVVSIELPRDTKGGAGHGSLIILGGNDVSDVKRGIEVALKELDRTFGDVYGNEA
                     GHIELQYTARASYALEKAFGAPIGRACGVIVGAPASVGVLMADTALKSANVEVVAYSS
                     PAHGTSFSNEAILVISGDSGAVRQAVTSAREIGKTVLATLGSEPKNDRPSYI"
     gene            complement(24093..24377)
                     /gene="pduA"
                     /locus_tag="OPY25_002451"
     CDS             complement(24093..24377)
                     /gene="pduA"
                     /locus_tag="OPY25_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduA"
                     /protein_id="HCS0928050.1"
                     /translation="MQQEALGMVETKGLTAAIEAADAMVKSANVMLVGYEKIGSGLVT
                     VIVRGDVGAVKAATDAGAAAARNVGEVKAVHVIPRPHTDVEKILPKGISQ"
BASE COUNT         5162 a         6730 c         7029 g         5597 t
ORIGIN      
        1 aaattgtgat tgaagccgac atttcataat acaaattaaa tataatcttc agctatatct
       61 aataacagga ggttatatga gcattagtcg tcgttctttt ttgcaggggg taggcatagg
      121 ctgctctgcc tgcgcgctgg gcgcttttcc gcccggggcg ctggcgcgca acccgattgc
      181 cggcattaac ggtaaaacca cgctaacgcc aagtttgtgc gaaatgtgtt cctttcgttg
      241 ccctattcag gcgcaggtag tcaataacaa gaccgttttt atccagggca atccttctgc
      301 gccgcagcag gggacgcgca tatgcgccag gggcgggagc ggcgtcagcc tggtcaatga
      361 cccgcaacgg attgtaaaac ctatgaaacg caccgggcca cgcggtgacg gtgaatggca
      421 ggtgattagc tggcaacagg cttaccagga aatcgcggcg aaaatgaatg ccatcaaagc
      481 gcagcatggc cccgagagcg tggctttctc ttccaaatcg ggctcgctct ccagccatct
      541 tttccatctg gctacggcct ttggttcgcc taataccttt actcacgcct caacatgccc
      601 tgccgggaaa gccattgcgg caaaagtgat gatgggcggc gatctggcga tggatatcgc
      661 taacacgcgc tatctggttt cgtttggcca caatttgtat gaagggattg aagttgccga
      721 tacccatgag ttaatgaccg cgcaggagaa gggggccaaa atggtgagct tcgatccgcg
      781 tttgtcgata ttttccagca aggcggatga gtggcacgct attcgtcccg gaggggattt
      841 agcggttctg ctggcgatgt gccacgtcat gattgatgaa caactctacg atgcgtcttt
      901 tgttgagcgt tataccagcg gatttgaaca gttagcacag gcggtaaaag agacgacgtc
      961 ggaatgggcc gccgcgcagg ccgatgtccc agccgacgtc attgtccggg tgacacgcga
     1021 actggccgcc tgtgcgcctc acgctattgt cagtcctggt catcgcgcga cgttctcgca
     1081 ggaagagatc gatatgcggc gtatgatttt tacgcttaat gtgctgctcg gtaatattga
     1141 gcgcgaaggc gggctatatc agaaaaaaaa cgcgtcggtt tacaacaaac tggccggaga
     1201 aaaggtcgcg ccaacgctgg cgaaactcaa cattaaaaat atgccgaaac cgacggcgca
     1261 acgaatcgat ctggtcgcac ctcagtttaa atatatcgcc gctggcggcg gcgtggtgca
     1321 aagcattatt gacgcggcgt taacccagaa gccttacccg ataaaggcgt ggattatgtc
     1381 gcggcataat cctttccaga ccgtcacctg tcgttcggac ctggtaaaaa ccgttgagca
     1441 actggatctg gtggtcagct gcgatgtcta tttgagcgag agcgcggcat atgccgacta
     1501 tctgctgccg gaatgcacct atctcgaacg ggacgaagag gtatccgata tgtcgggtct
     1561 gcacccggct tacgctctgc gccaacaggt cgtagagccg attggcgagg cgcgtccgag
     1621 ttggcaaatc tggaaagaac ttggcgagca gttgggatta gggcagtact atccgtggca
     1681 ggatatgcag acgcgccaac tctatcagtt gaacggcgac catgccttag cgaaggaact
     1741 gcgacagaaa gggtatctcg aatggggcgt tccgctgcta ttacgcgaac cagaatccgt
     1801 tcgtcagttt acggcgcgtt accccggcgc tatcgcgacg gacagtgaca acacctatgg
     1861 cgaacagctt cgcttcaaat cgccctccgg caaaatcgaa ctttattccg caaccctgga
     1921 ggaattgctc cctggctacg gcgttccgcg cgttcgtgac tttgcgctga aaaaagagaa
     1981 tgagctttac ttcattcaag gcaaggtggc cgtgcatacc aatggcgcga cgcagtacgt
     2041 acctttactc agcgagctaa tgtgggataa cgcggtctgg gtccatccgc aaacagcgca
     2101 agaaaaaggc attaagaccg gcgatgagat ctggctggaa aatgccacgg gtaaagagaa
     2161 aggtaaggcg ctggtgacgc ccggtattcg cccggatacg ctttttgtct atatgggatt
     2221 tggcgctaaa gctggggcta aaacggcggc gacgacacac ggtatccact ctggcaattt
     2281 actgccgcac gtgacgagtc cggtatccgg tacggtagtg cataccgcag gcgtgacgct
     2341 gagccgggca tgagggagga gggaaccatg aatcatttaa cgaatcagta cgtcatgctg
     2401 catgatgaaa aacgttgtat cggctgccag gcgtgtaccg ttgcctgcaa agtgcttaat
     2461 gacgtaccgg agggatttag ccgcgtacag gtacaaattc gcgcccctga acaggcatcc
     2521 aacgcactaa cccattttca atttgtccgc gtctcctgtc agcactgtga aaatgcgcca
     2581 tgtgtcagcg tttgtcctac cggagcgtca tatcgtgatg aaaacgggat cgtgcaggtg
     2641 gataaatcgc gctgtattgg ctgcgattat tgtgttgccg cgtgtccttt ccatgtgcgc
     2701 tatctgaatc cgcaaaccgg cgtcgccgac aagtgtaact tctgtgccga cacgcggttg
     2761 gcggctggcc agtctccggc gtgcgtatcc gtttgcccaa cggacgcgct gaaattcggc
     2821 agactggatg agagcgagat ccagcgctgg gtcggtcaga aagaggtcta tcgccagcag
     2881 gaagcgcgta gcggcgcggt cagtctgtac cgtcgtaaag aagtccatca ggagggtaaa
     2941 gcatgaatac tatctgggga gcggaactac attatgcgcc agattattgg ccgctgtggt
     3001 taatttacgc aggcgtcgtg gtgctgctca tgcttgttgg gctggttatc catgcgttat
     3061 tgcgccggat gctggcgcca aaaacggcgg gcggcgaaga gcatcgtgac tatctctact
     3121 cgctggcgat tcgccgttgg cattggggaa atgcgttact gtttgtttta ttactgttaa
     3181 gcggtttatt tggtcatttt tctctcggcc ctgtagcgct aatggtacaa gtgcatacct
     3241 ggtgtggttt tgccttactg gctttctggg tcgggtttgt gctgatcaac ctcaccacag
     3301 gtaacgggcg tcactatcgg gtaaattttt ccggactagt gacgcgctgc atacgccaga
     3361 cccgttttta cctttttggc atcatgaaag gggaagcgca tccgttcgcg gcaacagagc
     3421 agaataagtt caatccactg cagcaactgg catatctggc gattatgtac gcgctggtac
     3481 cgctgttaat catcaccggt ttgctgtgtc tctatccgca ggttgcgggt ctgggccctg
     3541 tgatgctggt gctgcatatg gcgcttgcta tcatcggctt actgtttatt tgcgcgcatc
     3601 tctatctgtg tactcttggc gacacgccgg gacaaatttt ccgtagcatg gttgacggct
     3661 atcatcgtca tcgtaccgcg ccgcgcgggg ataagtccgc cgtctgagcg tatccataaa
     3721 ataaagtcag caagaaaatg tgccttgtgt cacattttct tgcaatttat ccatgtttgt
     3781 ttaactgaac ttccgtaaaa agaacggcaa attgagacca tcctgaagac atgctgttga
     3841 aacgccgttt gtttattgcc gcttctttat tcgcgatgca cctttctcct gcgcttgcgg
     3901 ccgatgccgt aagttttgct ccccaaccgc cagccattga tgcaggcgcc tgggtgttga
     3961 tggattacac tacgggacag gttcttaccg ccggtaatga acaccagcaa cgtaatcccg
     4021 ccagccttac caagctaatg acgggctacg tcgtcgatcg cgccatcgat agtcatcgta
     4081 tcagccctga cgatatcgtc accgttgggc gcgacgcctg ggcgaaggat aatccggtgt
     4141 ttgtcggctc ctcgttgatg tttttaaaag aaggggatcg cgtgtcggta cgcgatttaa
     4201 gccgtggctt aattgtggat tccggtaacg atgcctgtgt ggcgctggcg gattatatcg
     4261 cgggcgggca gccgcagttt gtggcgatga tgaacagcta tgtgaaaaaa ctcaatttgc
     4321 aggataccca ttttgaaacc gtccacggtc tggatgcgcc gggacaacat agctccgcgt
     4381 atgatctggc cgtactctcc cgggcgatta ttcacggcga acctgaattt tatcacatgt
     4441 acagcgagaa aagcctgacc tggaacggca tcacacagca gaaccgcaac ggcttgttat
     4501 gggataagac catgcatatc gatgggctta aaaccggaca cacatcgggg gcgggattta
     4561 atcttatcgc atcggcggtg gacgggcagc gtcgacttat cgccgtcgtg atgggagcga
     4621 aaagttcgaa aggacgcgag gaacaggcgc gaaaactgtt gcagtggggc cagcaaaact
     4681 ttgcgacggt gcagattttg cacagcggca aaaaagtggg cagcgagcgg atctggtacg
     4741 gagacaaaga aaagattgcg ctgggtacgg aacaggattt ctgaatggcg ctgcccaaag
     4801 cggaaattcc gcatatcaaa gcaaaatatg tgctggatag aaaagagctg gaggcgccaa
     4861 tcgccgccca tcaacgggta ggtgaaatag agctctacga tcgggataaa ctgatcgctc
     4921 agtggccgct ggtcactctg gaatcggtgg gtaaaggcgg tatgttctct cgtctgagcg
     4981 actattttca gcataaagcg taagccgttg tcacacaccg ttcaccgtca tctgaggtgt
     5041 caaaagggcg ggattgcgag gttgctcaca aaatgatcac gctgtccttg tgaccgtaaa
     5101 aggctgtaat tatactgtac attaatacag tatagtaaag tgacggaggc agcatggatt
     5161 acgaaatcag gcaggaacaa aaacgcaaga tagccggttt ccacatggtc ggtccatggg
     5221 aacacaccgt gaagcagggt tttgaacaac tgatgacgtg ggtggatcga cagcggatcg
     5281 tgccagttga atggattgcc gtctattacg acaatccaga tgtcgtacct gcagaaaaac
     5341 tccgctgcga taccgtggtg tccgtggcag agaatttcat cctgccggac aatagcgaag
     5401 gcgtaatcgt gaccgccatt gaaggcggcg aatatgccac tgctgtcgcg cgagtggaag
     5461 accgtgactt tgcgaagccg tgggaacggt tttttgatgt cctcgagcag gatagcgctt
     5521 atcagatagc ctctgcgccc tgttttgaaa cctatctgaa taacggcatg gaagatggat
     5581 actgggatat tgaaatgtat attccggtac agcggaagtg atcgactggt ttcctggctg
     5641 aaaagagcgg acggataatg tgttccgtcc gccagtgcgc tatttttgct ataaagcagg
     5701 tacaatgcat tttttgccat tcccgtaagg agcgcaagcg tgcgtgccga taagtcatta
     5761 agcccttttg aaatacggtt gtaccgtcat tatcgcatcg tgcatggcat acgtatcgcc
     5821 ctggcgttca ttcttacctt tctgctggtt cgtctgtttt ctattcccga gggcacatgg
     5881 ccgctaatca cgttagtggt gattatgggg cccatctcat tctggggaaa tgtagtgcct
     5941 cgtgcttttg agcgcatagg cggtacgatt ctgggcgcgg cgttagggct ggtggcgcta
     6001 cgcctggagc tcttttcctt accgctgatg ctggtgtggt gtgcgatagc gatgtttttg
     6061 tgcggctggc tggccttagg gaaaaaaccg tatcaggcgc tactgatagg cataacgctc
     6121 gccgttgttg tcggcgctcc cgctggtgat atgaatacgg cattatggcg tggcggggat
     6181 gtgattttgg gggcgctact ggcaatgttg tttaccggca tctggcccca gcgcgccttt
     6241 ttgcactggc gcatccaact ggcgcattgc gtcacggcgt ataatcgggt gtatcaggca
     6301 gcgctgtcgc cgaatttgct ggagcgcccc cggttggata aatatttgca acggttgctg
     6361 aacgatgtcg tcaaaatgcg cgggctgata acgccagcca gtaaagaaac ccggatacaa
     6421 aaatctattt tcgaggccat tcagaccatc aaccgcaatc tggtttgtat gcttgaatta
     6481 caaatcaatg cccactgggc gacgcgcgcc agccattttg tgatgcttaa cacgcacaca
     6541 ttgcgtgaaa cccagcagat gacgcagcaa accttgctaa cgatcgccca cgcgttgttt
     6601 gaaggcaacc cgcagccggt actagcaaat accggtaaac tgaatgatat tgctgccgag
     6661 ttgcgacagc taatgaacga gcagcagggc gacgcggtgg ctgaaacccc catccacggc
     6721 tatgtttggc taagtatgga aacggcccga cagttggaac tgctttcaca cttgatctgc
     6781 cgggctttgc gcaaataaaa agcagatggg gtgaatgaat ttgttgctgc ttcgattcag
     6841 caaagattaa gagtatgata ctaatataag gataaaatga gtgctactgg caacgatttt
     6901 atccccgaac cttcaggttt ccccagacgg cgacgtaacg gtgtttcttc tggcggcttg
     6961 aagtatgacg gggataaacg taatgtttat ccactagcag ttgcttaacg aatccgaatc
     7021 tcacattatc aggggtgtaa aaatggaaac aaccaagcct tctttccagg acgtgctgga
     7081 gtttgttcgt ctgttccgtc gcaaaaataa actgcagcgt gaaattcagg acattgagaa
     7141 gaagatccgt gacaaccaga agcgtgtgct gctgctggac aacctgagcg actacatcaa
     7201 gccaggtatg agcgttgagg cgattcaggg tatcatcgcc agtatgaaaa gcgactatga
     7261 agatcgcgtt gatgactaca tcattaaaaa tgccgaaatc tccaaagagc gtcgcgacat
     7321 ttccaaaaag ctgaaagcga tgggcgaaat gaaacacgcc gatgtaaaag ccgaataatg
     7381 cgctacggca gtgggagcgt atatcaggct ctcactgcag tttgaccccg cctgtgacca
     7441 tcttgagtaa atgttgtttt ggccagtgtc gggtaagttt tttctctgcc agcttacctt
     7501 tcagacgcgc aatatcatga cgtttccggt ccagcatcag acccaccacg ctaccgctat
     7561 gcgccacgtt caatccgtat aaatcacact cttcgaccag cgacagcagg gcggtaaagc
     7621 ccggcttagg taacagcgtc tggctggcga tagcgctaag cgtagccgcc tcacccagtc
     7681 ggagcggatt ttgcgttata caggcttcct gcaccagatt ccaggcctgc tgcaaggttg
     7741 gtgaacttgc tattaatttc tgctggcgag ggagacggtg gtaatcttgc gtgcgcagtg
     7801 tgaccgggct ttccagtacc agcaaatcga ttggcggcgg tggctcgcag gcgatttgcg
     7861 tggccgcatt attatgatca aacagcgtta actgatgaaa aacggtgcta tcagtgggtt
     7921 cgattgagac gcaaagctgt gcaagggtgg tttcatccag cgaatggcca agatgatgcg
     7981 ccgttgccac cgccgtagcg gcaatatctg cggtgctgct ggccatgcct ttggcaacgg
     8041 gaattgacga acgcacatcg acgcgaatct cgttactcca gtgcgcagga tactgccagt
     8101 gcgccagaac gcgctccacc atcgcccgcg acaatggacg ctcgtttacc aacggcggcg
     8161 cagccgtgac tgctacggtg ctgtaccagt caacggggca ggagaccagt ttctcactgc
     8221 ccagaatcca tccctggata agttccccgc atgaggcggg gcattgcgca acagccacgt
     8281 tatcaccttt caggtacgaa tagtgtgcgc gcatagtgtc atggtaaaag cgttattacc
     8341 atgacttgcc gcaatgcgtc gtatacccct ctcaggctgg tacacaaagc ccttccgtgg
     8401 ccggtagcgc aatgcgcata acgtcttgtg cgatcattaa ctcttcgttg gtgttgatga
     8461 cggcgacttt caccagggcg ttctccgtct ggataaatgt tgcattacgt tgatttttct
     8521 cttcatcaac ggctaagcct aaaaattgca aattatggca aaccgccgat ctggcgcgcg
     8581 ctgagttctc gccaattccc ccagtgaata ccagagcatc cagtcctccc atttgcataa
     8641 tatagccacc aatggtggcg cgaatgcgtt cggcaaacag cgtgagagcg agtttagcct
     8701 gccggttacc ggtattggct gcctgttcga catcgcggta atcagacgac acgccagaaa
     8761 cgcccagcaa gcctgactca ttatttaata actgattcaa ctgttgcggc gttttgcatt
     8821 cgcgctgggc tatccacggc agaatagagg gatcaatatc tccgctacgg gtgcccatca
     8881 tcacgcctga ctgcggcgta aagcccatcg acgtattgac cgaacgtccg ttcttgatgg
     8941 cgcagacgct gctaccgttt ccaagatgac aacaaatcac ccgtaatgcg ctgagtggta
     9001 cgcccagctt ttcagccaga acgccgctga catacttatg gctggtgcca tgaaagccat
     9061 aacggcgaat ccccagttca gcgtaataat gccagggaag cgggtaaata taggcgggtt
     9121 catccagcgt ctggtgaaat gccgtatcaa acacggctac agaaggggca tcaggcaaca
     9181 gttgacgaaa aacgtgaata cccaacgcgt ttaccgggtt gtgaagcggg gccagttcag
     9241 caagacgttc gatttgcgct aacgtttcat ccgtgaccag cgtcgagtct ttaaaaaact
     9301 caccgccgtg cgccacacga tggcccaccc cgtcaatgtc ccgcagactg ttaatgattt
     9361 gataacccag cagcttttcc agaagcagcg ttaccgcatc gcgatgatcg gcaacgggga
     9421 cggtttcctg ccatttttgg ctgtgcgtct taattgtcac ctgcgcatcc gccataccga
     9481 tacgctcaat cagcccctgg cagagcatgt cgccctgcgg catctccagc agctggaact
     9541 ttaacgatga gctgccggcg ttaatggcca ttattttgta agacataaag gttccttcga
     9601 attcagaaaa tccagcacgg cgtcgagacc cgaattattc aacgcgctgg taataaaaat
     9661 ctgccgggcg ccagcctgcg taagccattg tgcgaccagc gaaatacgct gcgggtcggc
     9721 gagatcggct ttggtgacaa ggccaatcgt cgggcggttc atcgggacgg taaaacccgg
     9781 agaaaacggc gaccactgag cgtcggcatt taacaccagg gcgataacgt cggcctcgca
     9841 ggcgctggtc agcagggcgc tgtacaggca gcggttctcc aggtattcgc ccggcgtgtc
     9901 gatagccatc ggcgaccatt caatggcctg ggttttcttg taatggagcg cttcgccacg
     9961 caggctttgg gtcagcgaag ttttcccgca ctggctgggg ccgataaaca tcagacgctt
    10021 cattggatta cgtccgggtg atcgagcagg tagtgaactg catcatctcg cccagggtgc
    10081 gcgttacctg cttgagggca tattccacgg cggaaacatc gccggtcagc accacagcac
    10141 cggtaaagcg gtcaagaaaa ccaatctcca ccgcgccgga ttttgtagca atatcgcagg
    10201 cgataatcga cgcttcgctg ggcgtgatgg tgaggatgcc aatggcggaa accgcatcct
    10261 gcaggcccag cttcttaaat aaatctttcc ccggattagc aatcaggtgc gcgagggtca
    10321 cctgtttccc cggcacgtat tcctgaatca tgcgatccgt tgtcggttgt ctttccatta
    10381 tccctccacc atctgtcgcc acatggcttc atgcgagcgt gggatcaccg aacggtaaac
    10441 cagcagccct ttttcgcccg cgctttcgct ggcgaccgtc acggcgttat tgacgtcaga
    10501 aacgtcgccc gccaccacca tgtagcattt accgccgatg ccgaaggcca tatgcacccg
    10561 caccagggtg acgtttgagc ctttcaccgc ccggtctgcg gcgctaatgc aggccgccac
    10621 gctccaggtt tcgacgatgc cgaccgcctg acgcttatcg acgctgttca ggccgctgat
    10681 ggccggaagt acgctgggat gaatatttgc cagcaccagg ctgtcgacga gcatctcgcc
    10741 ggcctgcgac gtaccggttt caatggcctg ctggatagcg ccgatatcgc cgcccagcat
    10801 cagtaaaaac ttacttgggc agatggtctt gctgaccagt agatcgacgt tggcgctttt
    10861 cagcatggca tcaccaagct ccatgccttt ggcgatgctg gtgagttcta aaattcctat
    10921 agcctgagac atggttaacc tcttacaaca gtgatggcct gttcgctgat ggccgaaaca
    10981 atgccgtcga tgctggcgtg aatggatgcg ccgagcgcgc caggcgggac atcggcaacg
    11041 cattgcccgc gagtcacgcg ctcgccgacg gcaacagtcg gtactgcgct ggcaccaata
    11101 tgctggcgca gctgcaaagt gactttttct actgacggct cttcttcaac cagcggcgct
    11161 tcctggtacc aggggcttag tcccagtttg gcgatcagcc gcttcaccgg caccaggcga
    11221 tatttcgcca tttcgtcggc cggattcagc ggcccttcgt agcgctggtt ttgcgcccgc
    11281 agctcgcgtt ttaacatgcg gttgatgcgc atcggcgaga tcccgaccgg gcaggccacg
    11341 ctttcgcaaa cgttgcattc cgagcaggta agggcgctca gcagcagttg cggcgtggca
    11401 gcctgatgaa agttcaccgc ccgcaccagc aggtgcggag agagttcgtg gccgatcaga
    11461 tgtcgtgggc agagatcggt acagagtcgg cactgttcgc agacggtgcg cgcgacggaa
    11521 agcactgtgc gctcgtcctg catcctgcgc tggataagcg gatggctttt tgggagcacc
    11581 agcaggccgc cggtagtttt cgtcaccggg ttatcaagag aggtaatcag gccacccatc
    11641 atcgggccgc cgttaataaa accggggttg tcgaccgtcg cgccgccagc cagcgccagc
    11701 acttcatgca gtgacatgcc gacaggaacg gtaacggtca acggtctggc gaccgcgccg
    11761 ttcacggtca acgtgcgacg agtgaccgga aactgctgct cgaccgcccg ggcaatattc
    11821 agcaccgttt gcacgttatt gacgactacg ccgacgctgg caggcagcgc ggcaggggcg
    11881 acccgacgac cggttgccat ccagatagtc agcacctcat cgcccgcggg atatacatcc
    11941 ggcaggatat gcaggcggat accggctggc agtagtgggg agagggcgtc gatggcccgg
    12001 cggtattttt ctttcagggc aatcacccct tcgcgcgcgc cggttgccgt catggcgtac
    12061 tgcacgccgc ggacaagacg cgcggcctgc tgccacatca gttgctggtc aactttgagc
    12121 atcggttcac actcggcggc gttcaccaga aaaatctcta cctgcgcctg tagcttaacg
    12181 tgggcgggaa aacctgcgcc gcccgcaccg acaacgcccg ctgcgcgaac gcgctcacga
    12241 atttcatcgg cgctaaggga catttaaacg ctgttgatgg cggcgctcat agcagttcct
    12301 ccagcagttc acgaatttcc tcggcgctgg ccgggcgcgg gttggtgcgc aacgtgacat
    12361 ccgccagcgc ggcctgcacc atcgctggaa tacgtgcgga aaagtcggat cttccttctt
    12421 ttagcgcaac ggccagtgag ggaagggcac agcgttgctt aagcagttcg atttgctgaa
    12481 tcagcgcatt gatcgccgtg acatcgttgg cttctgccgg gcaaaaaccg caggctttgg
    12541 ccagccgcgc gtagcgtttg gctgcgcgcg gaactccggc gttaaaacgg atcaccgtcg
    12601 tgagcagcag cgcattggcc aggccatgcg gaagatgaaa ctgtccgcca agctggtggg
    12661 ctatcgcgtg gttaagcccc agccccgcct ggctgaaggc catcccggcg agcgttgagg
    12721 cgttatgcat ttttcctcgc gtcgccacgc agtcgccttt ttccaccgcc gtcggcagat
    12781 actggaacac cagtttggcg gctttttccg ccagcgcgtc ggtaaagtcg ctggcgtgcg
    12841 gtgacaccca ggcctccagg gcgtgggtca gcacgtccat gccggtgttg gcggtaatct
    12901 gcggcggtac gctgaccacc agctccgggt cgaggatcgc catatccgga tacagcgcat
    12961 tgttgaacag cggatacttg atgcctttat ccggatcgct aattacgcag gcgctggtga
    13021 cttccgaacc agtgccgctg gtggtcggga tcgccacgca ggtttcgata ttgatgccgc
    13081 tttgttggct aaaccagaca atcgctttcg ccgcgtccat tgccgagccg ccgccaaaac
    13141 caatcaccac ctgcggctgc agggcctgca tttgcgcaat gccctgcacc acggtatgga
    13201 tggtggggtc cggcgttatc tcgctaaaga cgctgatgcg gttatctgcg ggcagcgcgt
    13261 tacacagggt atccagcagc ggcgagcgtg ccagaaagcc atcgcagatt atccagatgt
    13321 gcttattggt aaagcgcttg agcaccgcca ggctgccctg accgctgtac aaccgcgttt
    13381 gtagtgagaa ggtgttcatc gcgacctcgg ttagcgaata gaaaagccgt tggtcagcac
    13441 gcagcgccgg gagcgggcaa aagtacgcgc tgacgttgtt ccttcaccgg ttggcgtggc
    13501 aatggtaaag gtggtaaagc cttcgccgcc gacgccgatc ccggcataag aagggccgtt
    13561 tttgacgaat atcgaggttt gcagggtgcg ggccgcgagg ttcaggcgcg acacgttctg
    13621 cgagtgcatg atcgcggtgt gatgcaaccc ctcttcaacc ttcagggcca gtgccagcgc
    13681 gctatcgaaa tcgttaactt ttaccaccgg cagcatcggc atcagctgtt ctctggtgac
    13741 ccacggatcg tcagcgttaa ccagcgcaat cagcagacgc ggcgcttttg cagggacagc
    13801 gatcccggcg gcttccagca tggccgatgg gctcttgccg accagttttt tattcgcctg
    13861 gccttcaggc aggcagacgg cgcggagttt gtcggtatcg gcagggctta gcagcagcgc
    13921 gccgaaggtt tgcatttgct gcaccagacg ttcggcgacg ctctccacca cgatcaggct
    13981 cttctcggca atgcagggca ggttgtaatc gaatgacgcg ccgttgatga tatcttccgc
    14041 cgctttcacc aggtccgctg tttcatcaac gatgcagggc ggattgccag cgccagcgcc
    14101 aatcaccttc ttaccgctct tcatgcccat ggccacaatg ccggggccgc cggtaatagc
    14161 cagtaccgcg attcgcgggt gggccatcat ctgctgggtc gcttcgaaag tcggttccgc
    14221 cacggtcacc accagattgc ggatgccgca gcagcggaag gcaatctctt caatcagact
    14281 aatcagcttc agagagacct ttttcgctcc cggatgcggg ctaaagtaga tactattgcc
    14341 cgccgccaac atgctgatgc tgttattaat gatggtttcc gtcgggttgg tgcttggggc
    14401 gactgaaccg atgacgccaa acggcgagta ttcaaagagt accatgccgc cgtcaccggt
    14461 cagcgcggtg gtggtgagat cttctacgcc cggcgtgttg tccagagcag ccttgttttt
    14521 gaggaattta tcttctttgt tgcccattcc cgtttcattg gcgctctcct ctgccagagc
    14581 agccagcagc ggcgtcagct cctgacgcat cgcgctgata atggcgctgc gggtttttag
    14641 cgggcactgc tgataacgta agaacgcctg atgcgcggcg tcgatggcct cgctcacgga
    14701 ctggaaaatc cctttgccct gaggctgggc cggtgtttgc gctggcgtgg ttaattgctc
    14761 gctaagaatg gtgcgaatca gggtttcgag ttcagaagta ttcattgatg tgttcccacg
    14821 ttaatagccg cgatggcggt ctgtgctatg tccatgtcct gctcaacgct gccgccactg
    14881 atgccaagac ccccaattaa tatgccgtcg cgccataggg cgtaaccgcc gccaaaggtg
    14941 accacttttc cctgtaaatg actttccaga ccgtaaagcg ccgcgcctgg ctgaacgaca
    15001 tcgctcagct catgggtcgc cgttttcatc gccactgcgg tccatgcctt tttcggtgcc
    15061 agttcgctgc tgaccagcag ggcgtccggc atccgccagg tcacagtttc cgtgccgtgc
    15121 gcgtcaacga tgctgacgac taccggaacc tgcagttgct gcgcgcgttc aacggcggcg
    15181 cgggtgagct ggtgcagatc gtggaatgag agggccacgg gcgttgtctc cttgctgcgg
    15241 gtcggctggc tggcagccag atagcgcttg ctaacttcac ggatgatgtt ggcctggtgc
    15301 gcatcgctat cttccgcgcg ggccagggcg tacaggcagt ccgataagcg gttgatgtag
    15361 cgcatcagca cttggcgtac gttgacttca gttgccagtt caaccagacg gcgttcggcg
    15421 cggcgcgcca gcgtgcgggc aaaatgtaat cggctcgcgg cttcgcagcg tccgggtaaa
    15481 ataaagctgt gcagcggttc gacgcgggcc attgcccgat cgatagcggc ttccagggcc
    15541 gaaatctctt cgctgctgat gtagcgctgt ttgggcgatg gctgctcgct gtcgctggcc
    15601 agctctgcgc taaaccaaaa aagttgctgc tggatggcct cgagtaaggt gcggtgattt
    15661 tcatccgcag cggcgcaggc gcacaggctc agcgcggcgt tcagttcatc cagcgtgccg
    15721 taggcttcaa cccgcgggtg ggttttgctc acccgctggc cggtaaacag tgatgtggtg
    15781 ccagcgtcac ctgttcgggt ataaatcgcc ataaccgccc cttaacgcga aagcgtatct
    15841 acaatgccga caacggcgag gtcgatggcc tcatttggcc cggaaaaaac gtgcctggcg
    15901 ctggagccgc cgctgagcaa aaccagttcg ccgacgcccg cgccgacgga gtccacggcc
    15961 acttcatcgc cggaggtggg cgaggcgggg agttcgccat cggcgctgac ccgacgcacc
    16021 agcagcagct tttcccaatc aaagaaggtg atttttgcgt ggagacaacc gcgcccgtga
    16081 ctcgtgccag atgcatgatt tactcctgct taattaattg aatattccgc gcattggccg
    16141 cgtcacgcgc catggcggtc acgatgcatt tgcggtggac aaccacacgc ccccggctta
    16201 gcagcgcgac atcgcgatag cccagcaccg aacccgcatg cagaaccagc ggcagtccgt
    16261 gctcgtcggt gaataccagc ggcagacgag ccagtttttt taccgggata accggcagca
    16321 gctggctgtg caggctgagc tgtacgcgga tgccaaacgc cagcgcgtcg tgaattttcc
    16381 gggctgcggc atcgtcggtt tctgcatccg caagctgacc cagcagcggc aggtcgacga
    16441 gcaggatgcg cagcgacgcg tgctgacaga acagcgctgg acagtcggca tcgcgaagct
    16501 gcgcaacgct cagcgttgcc gtgctcaggg cacgacgctg cagtcgggag acaatctcct
    16561 cgacaatgcg ctgcagagtt tcgccgttca tcgcgggcct accagccggg caaaggcctg
    16621 cgggttatcg gcaccagcgg cgttggcttc atcggtatca atgtgcattt cgaggcgcat
    16681 gtccggtgaa acgcgaatcg ccacattgtt gaaaatcagc ccgcgctcgt cgccttcaat
    16741 cgctaccgaa accctatcgc cgtgggagac cttcaggatc agcgcatcaa gcggcgacat
    16801 atgaatatgc cgctgcgcga cgataacccc ggaaggtagc tccagttcgc caaaggggct
    16861 gaccaggcgg atgccaggtg tgcccttcag gttgccggac attctcagcg gcgcggcaat
    16921 ccccagtgtt ctggcatcgg tacgcgatat ttctacctgg cttaccgagc gcagcgggcc
    16981 gagcaggcgc acatttttga gctgtccttt cggccctacc agggtgacgg tttgctccgt
    17041 agcatattgt cccggctgca gtagcgcttt tttttcgctg atgggatggc cgggaaacag
    17101 ccgctcataa tcctgcgcgg acaggtggat atgacggttt gagacgccca gcggaatagg
    17161 ccgctggcgc atctcgtcga gaactttacg gaccgttgat tgcagaagct ctttatccat
    17221 tacgcttcac ctcgcttgcc ggaatgaatg caaagcgtac gaggttcgcc cttctggcgc
    17281 ggacattttg gatccagaca cagattgcag ctgaccagtt ctgattcctg cggggcctct
    17341 tcggctggcg cttcagaaac gacatcagct atctctgacg cttcaggctc aggttcaatg
    17401 acggaggggg agggtgtctc tgcgagcagg atcccttctc cgggcctggc gataaccttg
    17461 tgggccacca gaccattccg ctgttcggca aattgcgcac cggtggtgat ggccgcctgc
    17521 acggaggcca catcaccggc aattttaatc accatccagc ctgaaccatt ggtcttttcg
    17581 agggcgagca gcgtgataga agcggatttc gccatgatat cggcgcagct gatagccagt
    17641 gccagaccac aaacttcaag taatcccagt gattgcttca cgcggtgctc cttattcgcc
    17701 atcgattagg ctgatttcgg taaaatggcc tcaacatcgc tgtgcggacg cgggataacg
    17761 tggcaggatt tcacttcacc cacgacgctt gccgccgcgc tgccggcatc tacggctgct
    17821 ttaaccgcgc cgacgtcgcc gcgaaccatg actgtaacca ggccagaacc aattttttcg
    17881 tagcccacca gctgtacgtt ggcggattta accatggcgt cggcagcttc aatggcgcct
    17941 actaaccctt ttgtttcaac cagtcccagt gcgttattca tactgcagtt ctcctgttgc
    18001 ttagctattc agatcccgga aagggatccc tttgaccagc cgtgccgcgt tattaccggt
    18061 gttgcgttgg gcctgactgt cctgatgatg catcagcgta aaaagcggcg ccgatgcggg
    18121 taaattcttg taatgtacga ccagcgagtg tcgatcgcag gcaatgccga ccagcagcgg
    18181 cgagctgcgc gccgcctgcc aggcgctgtc aacgacatct ccagctgggt gatgctgaag
    18241 caggaaaggg atgccttcct cttcaatgcc cagcagcact tcgtgccaga ggctggcgca
    18301 gtcgttgatg acggtaatga cgatagccgg ggcgctgtga ttactgtcca tatgcaaact
    18361 ccttgtgcca ggagagaatc agaccggtgg ccaccgcgtt tcttgggcct tcgctgccgc
    18421 gaatatttcc tcgcccggcg actaggcggt agtgcgccag cgcatcggtg accaactgcg
    18481 gaacttcgaa atccagcgac gagccgccga ccagcaccac gaacggaata tcgcgaatgt
    18541 tgccggttgg actgacctga cgcagcgcgc gcagggcgtt ggtgacaaag acgcgttctt
    18601 tagcgctgcg gcgaatggcg cgcacttttt ccagcgctaa gtcgccggga agcggcacca
    18661 gttcgtccgg tttcaccacg cagacgcggg cgaacaccgc aggaggcagc ggcgtcggga
    18721 agaactggac gctgccgtcc tcgtggcgta agtggaacag gctttcgacc ttagccagcg
    18781 ggtatttttt gatctcttcc gccagatagc ggtcttccag ccccagttcg cgggcaataa
    18841 tcatcgtgac catgtcgcct gccccggcga gatgggtggc gatgatttca cctttagggt
    18901 tgatgatgga ggcatcggtg gagcccgcgc cgaggtcgag gatcgccagc ggtcgggtgg
    18961 tacccggcgt ggtcagcgcg cccagaatgg cggcttcagc ctcagcgccg ccgatctgca
    19021 cgtcgatatt aagcttctgc tcaatttcac gggcaatcat cgccatttgc agacggtctg
    19081 atttcaccat cgaggcgatg ccgacggcct gctccagcga gaactccccg gccagaccgc
    19141 cggtgacgct caccggaacc gaggtgtcaa cggccagaag atcctgaatg aaaatctcgc
    19201 tgctcggctt attggttagc tcggccatgg tctggcgcac atgctccagc atgccgccga
    19261 tattggtccc ggcctcgccg ttgacgttgt cgagcttgcc gtagccgtcc accgctttca
    19321 tgatagcttc ggcaccggcg gcaacatcca cgcgcacggt acgaccctga gcctgcagct
    19381 ccaggttacc ggcgggtatt gcgcgcgctt tgacgtcgcc ggatggcgtt ttaaccacca
    19441 cggcggaacg gttgccaatc agcgcgcgcg ccatcgggac gatgtttttc gtctcatcgg
    19501 cgttgaggtt gaatacggtg gcgatgccgt aagggttaga gagggtttcg ataacctttc
    19561 ccggcacggc gacttcaatc gccgccagca tccccagcgg aatgcagtcg atgtacagaa
    19621 cttcatcgac aatcggtagc gatttttcca gccggttgct gaccagtacg ccatcgtcgc
    19681 gctgcaaaat gacgccggta atctggtatc cggcgcgcat tgaggcgttg ataacattgg
    19741 cgatatcagc aaaatcaaag gctgacgata ccaccagaat ataggacgag tccgccgggc
    19801 gggttaacag ctcctccggc gtaatcgtga tacccacacc aaggcctgct ccgcccggcg
    19861 tttttgggtt atggccgatc attgtcgatt cggtgatgat ggtttcggta atggtttcca
    19921 tcgccacatc gccaatcacc ggcgtggctt cgttaatgcg gatgagcgaa atatcgctga
    19981 cattgatccc cgcgcgcttt gcgacgaggg cgagcgcttc ctgaatgccg aacacgttac
    20041 gcaacgtgcc tttgatcccg gtgttttccg ccagcgcgct gtgtgtaatc gttagtgcgc
    20101 cagtctcatc ttgccgcgcc agtgcgactt ccgttgatga gttaccgatg tcaatgccag
    20161 ctatatatcg catcgtatat cctttttctc gtcgtacttc aaactgcctt tttgttggct
    20221 gcgttctttc acccgaatca cttactacag taagctcatc ggggttatga gggacatccc
    20281 tgtccctcac taaagccagc ctatggctgt tcaaattcgt tccagacgaa tttgtcactc
    20341 acttgccgcc tcaatgcatc tcgaattact tagagaaagc taatcgtcgc ctttgagttt
    20401 tttacgctca acgtacagcc ctgccgcttc acgaacgaaa gctgcgcaaa tctttgcctg
    20461 ataacggttt tcgagatcgt cggcgatagc gagcagctct tctttcgttg aacgatacgg
    20521 acgaagggcg ttgtagattt caagaatgcg atcgtccggt accgcggtca gttcggcggc
    20581 gcgttcgaag ttcatcgcca gccggtcgcg gcccgcatct ttggcgatag acgcctgtaa
    20641 gcgcagggtt ttcggggtaa tacgcatatc ctgagcggtg actttattgc tcagcacgtt
    20701 ttccagcgta aagtcgtcca gcgttttatt ggtggcggtt ttcacccatt ccgggtgttt
    20761 gttcgccagc gggtagtcgc tgacctttgc gctgcgggac gtgccgcctg ccgcaggagc
    20821 cgctgctggc gcatcgccct gcaggctgtt catgcggctc aatacgtccc ggaccatcga
    20881 ttcaattgcg tcggtattca tggagttatc ctttatcaaa gcgtcacgcg cagttcctgc
    20941 gggtttttgc ccgtcacgac gtacttggtc tctttaatgt gcaaaatggc cgactttgcc
    21001 tggtacttcg ggcgtgccat ctggtcattt agcgtaggga ccggctgcgg tgattcgcgt
    21061 ttcgcatagc gggcggcgtt tttaccaatc tgacggtagg tttccagcgt cagcagcggc
    21121 gcctgcggga acagctccag gttggagagc ggcggtagcc cctgctggtg gataaccgta
    21181 gtatctttcg actggatgcc gatggagatg ccggagccgc tcaggcggtt accttcaacg
    21241 gcgacgaacg ccacgtcgga agatttaaag cagcgaatca cgcgcgccct gataccttct
    21301 tcttcaatac cggcaatgac ttcgcgcagg atgctcttat gcggtaagcc gacgatatta
    21361 acagtctgtg ccaggccaaa tgccgggccg acggcgataa tgacttcgtc ctgctgagtg
    21421 ccctggcgtg cttcgcccac ttcggtcaga aagccgtcgc ccgcaggcgc agcggtctgt
    21481 ggtgctgtgg atgccgcagg cgtattaaac gagacgggtt tatcgctgcc cttcatatcg
    21541 cggagcacgt cttcaattat ctggcgcagc aatttttcat taatttccat ttctcacccc
    21601 ttaatcaatc tcgttgggat caagagcgcc agggatgttt ttaatctctt cccagcgttc
    21661 tccctgcagg cgataacctg ttgccggacc ggcatagtca ttgacgtcat taaccgcaga
    21721 gagcacttgt ccgtcgccga cgataatggc ggaggtgtgc aaatagtcgc cggttagctt
    21781 ggctttctgg atgttgagca tgtcctgggc cacgtcggta aacccgccct gcgccagcgc
    21841 tttaacgact tccagaccgt tgcggttttt attgatgatt tcctgggcga acttgatgtc
    21901 ttcgacgatg ttacgctccg gcatatcttt cgaaccgtgg gcataggtcg cggcttcaac
    21961 ttcttcatcg gtaatcggcg gcagccccat tccggcaaac acggcctgca gcgcgcgggc
    22021 ggctttgtta cggatggcga taacgtcctc ttcacgaacc gggcgcagac cgccgtccac
    22081 tttcaggtcg cgctggataa cgttgtagtc gtcaaagtct tccgcatctt cgttggaacc
    22141 ggcgaacatg ttgtcgtagt tcggcaccgc ggaataacca gaggagataa agtcggtacc
    22201 cggcaggaac tgcatcagca ggcgcgcggt acgacgcata tcggagtggg tgaaggtctg
    22261 gtcgttactg gaggagcatt ccagatccag cgaagagcag atcaggtttt ccgccagcac
    22321 ggcacgaatg cctgacggca cggcagacgg tacgccgata cagcttacgg agccattttg
    22381 cagaccctga acgccagccg ctttggtgat atagatgcag cgcgcctcca gatacagcat
    22441 ggatttgcct tcggcgtagc ccatctgcac ttcggatccg gagccggagg tgaagcgcat
    22501 tttcaggccg cgagaggcgt aggaagaggc taagaagcct ttcgaccatg gcgtatcgtc
    22561 accgtcggtg aagaccggct cggtgccgta aacggaaatg gtttcggcgt agcaggtgtg
    22621 gcccagcatg ccgagcttca gctcggtggc ttcttccagg gagcactgag tcagtacgcc
    22681 cggacgacca acctgagagc cgaccaacag cgcgatggcg ttgaacggcg cgtagcgtgc
    22741 taccgcaacc gtggtttctt gttcgtcaaa cccgcgccat gcgccttcgg cggcatcggc
    22801 ggcaatttgc accgggttat ccttgacgtt ggtgacgtgc gcctgctgag acggcgtgcg
    22861 gcgtgcgcgc attttctgca tcgccatcat catctcaacc acgttcatat gcgaaaccac
    22921 ttcaacaatt ttcgccgggg tcatggcggt ggtcagcgga acgatttcgc tgcgcttgac
    22981 gttcggatcg cagagcatgt tagccagctt gaccgaatcc atcgccatca cttcttcggc
    23041 gcggttcagg ttgatgccgt agcgggcgat aaagtggtcg atcaggtcga attcgctaac
    23101 cggttttccg tccagctcgg tcaccgcgcc gttaacgatt ttaatcgacg gttttggatc
    23161 gttcgggctt tccatcgcga taaagccttc ttcgatccac tccttaacga agccgtcctg
    23221 attcacaggg cgtttcgcca gtgcttcaaa tcttttcgat ctcatgaatc agcctcgtgg
    23281 gtatcagatg taggacgggc gatcgttttt cggttcagaa ccgagggtcg caaggacggt
    23341 tttgccgatt tcgcgggcgg aggtcaccgc ctgacggacc gcgccggagt cgccggaaat
    23401 caccagaatg gcttcgttac taaagctggt gccgtgcgcc ggagagctgt acgccacgac
    23461 ttcaacgttg gctgacttca gggcggtatc ggccatcagt acgccaacgg aagccggagc
    23521 gccgacgatg acgccgcagg cacggccaat cggcgcgccg aacgcttttt ccagggcgta
    23581 gctggcgcga gcggtgtact gcagctcgat atgcccggct tcgttgccgt aaacatcgcc
    23641 gaaggtgcgg tccagctctt tcagcgcgac ttcgataccg cgcttgacgt cggaaacgtc
    23701 gttaccgcct aaaataatca gcgaaccgtg gcccgcgccg cctttggtat cgcgcggcag
    23761 ctcaatgctg accacttcgg tgttggtggc tttcaccgct tcgtccgccg ccataatgtg
    23821 cgggcctgcg ccggtgcggg cgccgagaat gccgatggaa cgatagcgct tctcaagttt
    23881 catcgcgtcc agcagggcgg tatcgacgtt ggcgataacc aggccaaggg tatcgccaat
    23941 ggcggtcccg acaaattccg ttaaactgca gcttttttct gccatagccg tctctcgtat
    24001 aggttggggt tgaccaggga tggcctgttg ttccggcgtt gccacacggg caatcacctg
    24061 cgccatgatc tgttccacca gctcattgct gctcattggc taattccctt cggtaagatt
    24121 ttttctacat cggtgtgagg gcgtgggatg acgtgtacgg ctttcacttc acccacgttg
    24181 cgtgcggctg cggcacctgc atcggtggcc gctttgaccg cgccaacatc gccgcgcacg
    24241 atgacggtta ccagcccgga gccaatcttt tcatagccca ctaacatcac attggctgac
    24301 ttaaccattg catcagcggc ctctatggct gcggttaagc ctttggtttc taccattcct
    24361 agtgcttctt gttgcataaa gacctcgcat ggagtgttcc gatagttggg actataagaa
    24421 gatgcgagga aaaagaatgg ctgacttgct gttgagcatc agaaaataat gggaaagcaa
    24481 tatgactaaa ttgtcttttg cttttataac ttattgat
//
LOCUS       DAJVKX010000058        24149 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000058 DAJVKX010000000
VERSION     DAJVKX010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24149
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.058"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            182..1135
                     /locus_tag="OPY25_002452"
     CDS             182..1135
                     /locus_tag="OPY25_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HCS0928051.1"
                     /translation="MSDNNQAERQPADQHLQDKPQIFRTLRNIDLNLLTIFEAVYVHK
                     GIVNAAKILNLTPSAISQSIQKLRTIFPDPLFIRKGQGVTPTTYATHLHEYISQGLES
                     ILGALDLTGSYDKQRTITIGTTPSVGALVMPIIYQAIRPRYPQLLLRNIPVDDAESQL
                     SQFQTDLIINTHSYNNRSIQHHVLFSDTLEIVCRQHHPCLANAITEERLNSADHTFLM
                     LEGQHLSLLRQRLQETFPDQQISFSSYNIFTIASLIASSDLLGLMPTRFYDLFSRCWP
                     LERLPYAPVNSEQVEFSLHYNKLSLRDPVLENVIDIIREAF"
     gene            1341..2306
                     /gene="lipA"
                     /locus_tag="OPY25_002453"
     CDS             1341..2306
                     /gene="lipA"
                     /locus_tag="OPY25_002453"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HCS0928052.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVVTERDALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDAEEPQKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIRAKS
                     PEIKIETLVPDFRGRMDRALDILNATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPEEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(2393..2596)
                     /gene="tatE"
                     /locus_tag="OPY25_002454"
     CDS             complement(2393..2596)
                     /gene="tatE"
                     /locus_tag="OPY25_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HCS0928053.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGTAIKGFKKAMN
                     DEDAGVKKDVDGSVQAEKLSHKE"
     gene            complement(2724..3511)
                     /locus_tag="OPY25_002455"
                     /pseudo
     CDS             complement(2724..3511)
                     /locus_tag="OPY25_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
     gene            3602..3985
                     /gene="crcB"
                     /locus_tag="OPY25_002456"
     CDS             3602..3985
                     /gene="crcB"
                     /locus_tag="OPY25_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HCS0928054.1"
                     /translation="MLQLLLAVFIGGGTGSVARWMLSMRFNPLHQAIPIGTLTANLLG
                     AFIIGMGFAWFNRMTHIDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VLINLLGSFAMTALAFWLFSAAAAR"
     gene            complement(4043..4252)
                     /gene="cspE"
                     /locus_tag="OPY25_002457"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(4043..4252)
                     /gene="cspE"
                     /locus_tag="OPY25_002457"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HCS0928055.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVTAL"
     gene            complement(4440..5012)
                     /gene="pagP"
                     /locus_tag="OPY25_002458"
     CDS             complement(4440..5012)
                     /gene="pagP"
                     /locus_tag="OPY25_002458"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HCS0928056.1"
                     /translation="MYVAMIIRKYFLIIALLVMPWLAIPSVSAADKGWFNTFTDNVAE
                     TWRQPEYYDLYVPAITWHARFAYDKEKTDRYNERPWGVGFGQSRWDDKGNWHGLYMMA
                     FKDSFNKWEPIGGYGWEKTWRPLEDDNFRLGLGFTAGVTARDNWNYIPIPVLLPLASI
                     GYGPATFQMTYIPGSYNNGNVYFAWMRFQF"
     gene            5391..6776
                     /gene="dcuC"
                     /locus_tag="OPY25_002459"
     CDS             5391..6776
                     /gene="dcuC"
                     /locus_tag="OPY25_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HCS0928057.1"
                     /translation="MLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISAL
                     MGHKVLPASETSTGYTATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKENISHEMLDVAEITTTAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLLAAVLEFVRGFNTQNVFSGLEVAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LSIPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIM
                     VPGASSAVTGG"
     gene            complement(6830..7510)
                     /gene="dpiA"
                     /locus_tag="OPY25_002460"
                     /gene_synonym="citB"
     CDS             complement(6830..7510)
                     /gene="dpiA"
                     /locus_tag="OPY25_002460"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HCS0928058.1"
                     /translation="MTEPLTLLIVEDETLLAEMHAEYIRHIPGFNQIWLAGNLAQARM
                     MIDRFKPGLILLDNYLPDGKGITLLHELMQSRYPGGVVFTTAASDMETVAEAVRSGAF
                     DYLVKPIAYERLGQTLTRYQQRRRMLASADSASQKQIDEMFNAYARGEPKGDLPTGID
                     ALTLNAVMKLFADPTVRHTAETVAQALTISRTTSRRYLEYCASRHLIVAEIIHGKVGR
                     PQRIYHGG"
     gene            complement(7479..9140)
                     /gene="dpiB"
                     /locus_tag="OPY25_002461"
     CDS             complement(7479..9140)
                     /gene="dpiB"
                     /locus_tag="OPY25_002461"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HCS0928059.1"
                     /translation="MSYQKNKKLFPFFRQLAFPLRIFLLILVVSVFIVAALAQYLSAS
                     FEDYLASHVRDMAMNQAKIIASNDSIIAAVKNRDYKRLAIIANKLQRGTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKPGALERGESYFITGKGSIGMAMRAKTPIFDNEGNVI
                     GVVSIGYLVSKIDSWRLDFLLPMAGVFVLLLVVLMLLSWFFAAHIRRQMLGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPEGHITAINRNARKMLGLPSPGRQWLGKLIAEVVNPA
                     DFFTCQIAERRQDVMANFNGLSVIANREAIRSGEELLGAIISFRSKDEIATLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVREMVQGESQAQQQLIDSLRGAFAD
                     RQVAGLLFGKVQRARELGLKMVIVPGSQLHQLPEGLDSTEFAAIVGNLLDNAFEASLR
                     TQEGDNTIELFLSDEGDEVVIEVADQGCGVPEALREKIFEQGVSTRADEPGEHGIGLY
                     LIASYVGRCGGVITLEDNDPCGTLFSLFLPKVKKNDDRTINPIDR"
     gene            9525..10600
                     /gene="citC"
                     /locus_tag="OPY25_002462"
                     /pseudo
     CDS             9525..10600
                     /gene="citC"
                     /locus_tag="OPY25_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
     gene            10597..10893
                     /gene="citD"
                     /locus_tag="OPY25_002463"
     CDS             10597..10893
                     /gene="citD"
                     /locus_tag="OPY25_002463"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HCS0928060.1"
                     /translation="MKINQLAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGEA
                     IRATILEVLSRYDVRGVQLNVDDKGALDCILRARLETLLARASGIAALPWEDRQ"
     gene            10890..11798
                     /gene="citE"
                     /locus_tag="OPY25_002464"
     CDS             10890..11798
                     /gene="citE"
                     /locus_tag="OPY25_002464"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HCS0928061.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVNNSFIYPADALMFDLE
                     DSVALREKDAARRLVYHALQHPLYRDVETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVIDIENEILRIENACGREPGSTGLLAAVESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCAILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIELLHNLYAPTRKEVAHARLVVEAAEAAAREGLGVVSLNG
                     KMVDSPVIERARLVLSRAELSGIREE"
     gene            11808..13337
                     /gene="citF"
                     /locus_tag="OPY25_002465"
     CDS             11808..13337
                     /gene="citF"
                     /locus_tag="OPY25_002465"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HCS0928062.1"
                     /translation="MTQKNESQRQDRVVAWSRHAESELSAYQSAAKLDLQAQKPRDHK
                     LCASLEEAIRRSGLRDGMTLSFHHAFRGGDLTINLVMETIAKMGFKNLTLASSSLSDC
                     HAPLVEHIRNGVVSRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNID
                     VAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADSAKQVVMLTEQLLPYPHNPASIA
                     QDQVDLIVQIEEVGDANKIGAGATRMTTNPRELLIARSAAEVIAHSGYFNEGFSLQTG
                     TGGASLAVTRFLEDKMRSRNIVANFALGGITATMVNLHEKGLIRKLLDVQSFDRNAAQ
                     SLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEVDTHFNVNVLTGSDGVLRGA
                     SGGHCDTAVAAALSIIVAPLVRGRIPTLVDNVTTCVTPGSSVDILVTDHGIAVNPARP
                     ELAERLKAAGMKVVSIEWLRERAQLLTGQPRPIEFTDRVIAVVRYRDGSVIDVVHQVK
                     E"
     gene            13340..13786
                     /gene="citX"
                     /locus_tag="OPY25_002466"
                     /pseudo
     CDS             13340..13786
                     /gene="citX"
                     /locus_tag="OPY25_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459612.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
     gene            13758..14654
                     /gene="citG"
                     /locus_tag="OPY25_002467"
     CDS             13758..14654
                     /gene="citG"
                     /locus_tag="OPY25_002467"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HCS0928063.1"
                     /translation="MMPIPVNPTNASIQPQSLYDAWADLAWRAMLTEVNLSPKPGLVD
                     RLNCGAHKDMALADFHRSAEAIRHWLPRFMEYGASCTRLPPESVLAGLRPLGMACEAA
                     MFRATAGVNTHKGSIFSLGLLCAAIGRLYQLRQPIAAETLCATAADFCRGLTTRELRQ
                     NNLQLTAGQRLYQQLGLTGARGEAEAGYPLVIRHALPHYRALLAQGRDPELALLDTLL
                     LLMSLNGDTNVASRGGADGLRWLQQQAAVLLHQGGIRTPDDLVYLHRFDQQCIERNLS
                     PGGSADLLIVTWFLAQISQVNH"
     gene            14692..16233
                     /locus_tag="OPY25_002468"
     CDS             14692..16233
                     /locus_tag="OPY25_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HCS0928064.1"
                     /translation="MSLSKDNIWKLLAPLVVMGVMLLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDASELADPAFKASKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVTGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGVQISWLQWFLSFLPVGIILLIVAPWLSYVLYKPEVTHSAEVAAWAGGE
                     LKNMGRLSRKEWTLIGLVLLSLGLWVFGGKIINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFANTMSTHLEGFSPDATVIVLVLVLVLVL
                     VLVLVLVLVLVLVLVLVLVLVFYFAHYLFASLSAHTATMLPVILAVGKGIPGVPMEQL
                     CILLVLSIGIMGCLTPYATGPGVIIYGCGYVKSRDYWRLGAIFGVIYIAMLLLVGWPI
                     LAMWN"
     gene            16343..17149
                     /gene="rna"
                     /locus_tag="OPY25_002469"
     CDS             16343..17149
                     /gene="rna"
                     /locus_tag="OPY25_002469"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HCS0928065.1"
                     /translation="MNTIWHYSPLLAVLLTPIFAANADELQAQQYGDFTDYVLALSWQ
                     TGFCQSQHERRHREPDECRLQKEPANKADFLTVHGLWPGLPKSIAARGVDQRRWQRFG
                     CATRPIPNLPEVKASRKCSAPAPGLSPDIATALKEVMPGAGGNSCLERYEYAKHGACF
                     GFDPNAYFGTMIRLDKAIKDSALGQFLADNYGKTVSRAEFDSVVAQTWGQDNVKAVKV
                     NCHGNPAYLTEIQFSLKASMINAPLSSASFQPQPHPGNCGKQFIIDKAGY"
     gene            17384..17794
                     /gene="rnk"
                     /locus_tag="OPY25_002470"
     CDS             17384..17794
                     /gene="rnk"
                     /locus_tag="OPY25_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HCS0928066.1"
                     /translation="MSRPTIIINDLDAERIDRLLEQPAYADLPIADALNAELDRAQMC
                     SPQEMPNDVVTMNSRVKFRNLSDGETRVRTLVYPANMTDSSTQLSVMAPVGAALLGLR
                     VGDTIHWELPGGASTHLEVLELEYQPEAAGDFLR"
     gene            complement(17877..19115)
                     /locus_tag="OPY25_002471"
     CDS             complement(17877..19115)
                     /locus_tag="OPY25_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="HCS0928067.1"
                     /translation="MKALTYHGPHHVKVENVPDPGIEQPDDIILRVTATAICGSDLHL
                     YRGKIPQVKHGDIFGHEFMGEVVETGHDVKNIRKGDRVVIPFVIACGDCFFCRLQQYS
                     ACENTNDGHGAAMNKKQIPPPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
                     SDDKALFLSDILPTAWQAAKNAQIQQRSSVAVFGAGPVGLLTIACARLLGAEQIFVVD
                     HHAWRLRFAEERYGAIPINFDDENDPAEKIIEQTAGHRGVDAVIDAVGFEAKGSMTET
                     VLTNLKLEGSSGKALRQCIAAVGRGGVVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQT
                     HVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAMS
                     AQAAQKQATGVINPMPGGVV"
     gene            19338..19766
                     /gene="uspG"
                     /locus_tag="OPY25_002472"
     CDS             19338..19766
                     /gene="uspG"
                     /locus_tag="OPY25_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HCS0928068.1"
                     /translation="MYKTIIMPVDVFEMELSDKAIRHAEFLAQQDGVIHLLHVLPGSA
                     SMSLHRFAADVRRFEEHLQHEAETRLQTMVGHFSIDPSRIKTHVRFGSVRDVVNEMGE
                     ELDADVVVIGSRNPSITTHLLGSNASSVVRHATLPVLVVR"
     gene            complement(19834..20601)
                     /locus_tag="OPY25_002473"
     CDS             complement(19834..20601)
                     /locus_tag="OPY25_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCS0928069.1"
                     /translation="MEKYELPLVFFTVLSQMSVGMALVLTWRTLRGEVEGQRFYWLAT
                     GLVLALASIAAILHLAHPDRAYNALINLRHAWLSREILGATLFGAAVGVTFLAKGHKA
                     MALIASVFGVLLVAVQGMTYAAPAMVAIANGFTMLLFFITVWVMGCAAIPLLRLRPAV
                     PALRQGIVVCIAVLIAAPLVWLSGGTVMQMTARSWLASPFYLASLVCLALAFVASRHG
                     DSRPKLLFVLLFVGVFLSRLVFFGDTVSTIVNIGHLY"
     gene            complement(20601..21158)
                     /locus_tag="OPY25_002474"
     CDS             complement(20601..21158)
                     /locus_tag="OPY25_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCS0928070.1"
                     /translation="MRRAFLVNSDKCIGCRGCAMACKSFNQLEPDRFWRYVYPLDKDI
                     YPHEERAFYSLACNHCEHPACVAACPVEAYTKREDGVVVHNPERCIGCKNCIRNCPYG
                     APRFNEETRKAEKCSICYERLDIGMNPACVNACPVGALSIIDLDADPVPDNAVQYPPG
                     FPHMPQLNPGTRFILARQPKQPEDK"
     gene            complement(21155..23434)
                     /locus_tag="OPY25_002475"
     CDS             complement(21155..23434)
                     /locus_tag="OPY25_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCS0928071.1"
                     /translation="MSNETGHLNRRSFLKGIVALGTVAALPGGLLTSRCALAQPPVPF
                     NPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEGAPESTFTHGTPYVKGLSYPRRV
                     YSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDSSMLGLALTKYSGKF
                     GVLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWG
                     ANPAWCSMHSMKYIYQAREKGAKVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMAR
                     HLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWAAEICGLSAQVIRQLAEEFTAVN
                     PATAWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYNAMLQK
                     PPVGAIGIPGAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVAC
                     KNPFAQDFDRSKMKKAFEKLEMVVCADQFFNETVQHADIVLPVTTAFEEWNVDASYWH
                     YWLSINQPAIKPMYEAKCDLEIATMLSRTINKMAPGSCTFPQEFDHKRWLDQEFNDGM
                     AKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYK
                     PEAESKLPFHLFTPHVQFGLHSQFINLDWMQVFYPEPFVYIHPSSAKKKGISENDRVK
                     VFNNIGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQNVVADTPADMGLMKTGAPGA
                     AIHSQFADVVLIGKGESVA"
     gene            complement(23505..23987)
                     /locus_tag="OPY25_002476"
     CDS             complement(23505..23987)
                     /locus_tag="OPY25_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCS0928072.1"
                     /translation="MDSIYESLTELEKTGLTLRDFFNSHDSHSLKSAYVRLNPSAAVN
                     LTDRAWLEAEYDFNALFVGPGKLLAAPFASVYLEEDALVMGKATLEIRDFMAALGLSV
                     NQESNIPDDHISCVLELTTLLLANTRQTSQYCSTLTQYINNYLTKWVPLYIEKIKTHA
                     "
BASE COUNT         5758 a         6659 c         6018 g         5714 t
ORIGIN      
        1 atggcctctt cagtcctcat gatgaggaat tttccgtgaa caaaatcccg gccttgctgt
       61 tacttatctt attgaaatga ctaaaaatac attcataaga gtaattttaa aaccaactca
      121 taaatgcaaa atatactatt taatctatta ttcataatac gaatgaattc ggagccagag
      181 cgtgagtgat aataatcagg cagaaagaca accggccgat caacacctac aagacaaacc
      241 gcaaattttc agaacactga gaaatattga cctcaatctg ttgacgattt tcgaggccgt
      301 atatgtccat aaagggatcg tcaatgcagc gaaaattctt aacctgacgc cgtcagccat
      361 cagccagtcc attcaaaaat tacggactat atttcccgat ccgctgttta ttcgcaaagg
      421 ccagggcgta acgcccacga cgtatgctac gcatctgcac gaatacatca gccaggggct
      481 ggaatctatt cttggcgccc tggatcttac gggcagctat gataagcaac gcaccattac
      541 aattggcacg acaccttcgg tcggcgcgct agtgatgccg attatttacc aggccatcag
      601 gccgcgttat cctcagcttt tgctgcgcaa cattccggta gacgatgccg aaagccagct
      661 tagtcagttt cagaccgatc tcattatcaa tacccatagc tataacaacc ggagcatcca
      721 gcatcacgtc ctgtttagcg atacgcttga gattgtctgc cgccagcatc acccgtgtct
      781 ggcgaacgcc attactgaag agagactgaa cagcgcggat cacacctttc tgatgctgga
      841 gggacaacat ctttccctcc tgcgccagcg actgcaggag acatttcccg atcagcaaat
      901 cagttttagc agctacaata tttttaccat tgcctcgctg atcgccagca gcgatctgct
      961 gggactgatg cccacccgct tctacgactt atttagccgt tgctggccgc ttgaacgcct
     1021 tccctacgcg ccggtgaata gtgaacaggt cgagttctcg ctgcattaca ataaactgag
     1081 tctgcgcgat ccggtgctgg agaacgtcat tgatatcatc cgtgaggcgt tctgacaaaa
     1141 atgttgcatt caggtcacgg aagatatggg caaacagcac aaaacaacaa ctattttaca
     1201 ttttgccggg ctgtcaggct gctttatggc ccttatcaat gatatactgc gtgtcacaaa
     1261 ttcaaaaata gttgataaat acaactttcc cttgaattga aacgctttcc ttcgttattc
     1321 gcaactggaa cacgcacgct atgagtaaac ccattgtgat ggaacgcggt gtaaaatacc
     1381 gcgatgccga taagatggct cttatcccgg ttaaaaatgt ggtcacagag cgcgacgctc
     1441 tactacgtaa accggaatgg atgaaaataa aacttccggc ggattctacc cgtatccaag
     1501 gcatcaaagc cgcaatgcgc aaaaatggcc tgcattctgt ctgtgaggaa gcgtcttgcc
     1561 caaacctggc tgaatgtttc aaccacggta ccgctacgtt tatgatcctt ggcgccattt
     1621 gcactcgccg ctgtccgttc tgtgatgtcg cccatggccg ccccgttgcg ccggatgcgg
     1681 aagagccgca gaaactggcg caaacgatcg ccgacatggc gctacgctat gtggtcatca
     1741 cctctgtcga ccgtgacgat ctgcgtgacg gcggcgccca gcactttgct gactgcatca
     1801 ccgccatccg cgccaaaagc ccggagataa aaatagagac cctggtgcca gacttccgtg
     1861 gacgtatgga tcgcgcgctg gatattctta acgcgacgcc gccggatgtg tttaaccaca
     1921 acctggaaaa cgtgccgcgt atttaccgcc aggttcgtcc gggcgccgat tacaactggt
     1981 cgctgaaatt actggaacgc ttcaaagaag cgcacccgga aattccgaca aaatcgggtc
     2041 tgatggtggg cttaggcgaa accaatgcgg aaatcattga ggttatgcgc gacttacgcc
     2101 gtcacggcgt taccatgctg acgcttggtc agtatctaca gccaagccgc catcacctgc
     2161 cggtacagcg ttatgtcagc ccggaagagt ttgacgagat gaaagcagaa gccctggcga
     2221 tgggctttac ccatgccgcc tgtggcccct ttgtacgttc ttcgtaccat gctgatctcc
     2281 aggccaaagg catggaagtg aaatgatcgt gtaatagacg cttacatttc aggcaaaaaa
     2341 aaaccggcaa ctcgccggtt tttttactct gcggagcaag cgcattgcgc tattactctt
     2401 tatgcgagag tttttcagcc tgaacgctac cgtcgacgtc tttcttaacg cccgcgtctt
     2461 catcgttcat tgctttcttg aatcctttaa tcgccgtgcc caagtctccg cccagcgtac
     2521 gtaacttctt ggtaccaaac agcagaacaa ccagtgcggc aaccaccagc agtttggtaa
     2581 tactaatctc acccatagat accttcttca ctaaaaacag gctgcgtaac gcgccggatt
     2641 aacctgagaa tattaacggt ctttcgacgc gcgcacacaa tagcaatctg taacaaggtg
     2701 aatcaagctt tgcgtaaaaa acatcataat aattgcggtg gcgcaaatcg tcgttgctgc
     2761 aaaagaggaa gttgctcccg cacctggtct attcgttctc tgaatatttc cgcgacgatc
     2821 agcgccggac gatcggctgc cgcggctatc gttaccccca acggtcgata atacgacttt
     2881 gaccaatatt acgattacca cactccccgg ccgcaatcat atagcaggtg gtatccagcg
     2941 ctctcgccgc cagcagcgtc gaccactgct gctctttcaa cgggccgcga acccagcccg
     3001 tcggcagcgc caatacgtca gccccctgta aagccagcgc taacgccata tccggaaagc
     3061 gcaggtcata acaggtcata agacccacct taaccccctc cacgtccagc acaggcgcga
     3121 taacggttcc ggcatcaata ctttgggatt cttgcatcga aaacgcatca tagagatgca
     3181 gcttcgcgta acgcgcgaca atgtgacccg cccgtagcgc caccagcata ttaaccgccc
     3241 gtccaggcgt tgacgggaca aggatagtga atatcgtcgt catattatta tgagcgcttt
     3301 cttccagaag ccgcgtcata aacgcgccat ccagcggctg cgcggcgcga atcggcaggt
     3361 caaggtcgat gtcatctcgc gctaatatcc cctcaggcaa caccagaagc gatacgccgc
     3421 ggcccgccgc ctgagccatt aacgaaacgc aaacttgcac attctcttcc catacagaac
     3481 tcaccacaaa ctgcccggct gcaacgaaca tatcccctcc cacacctctg tcaggactcg
     3541 ccaattatgc gtgttcggcg ttacactcct cttgtatagc aattaaataa aggattcggc
     3601 agtgttacag cttcttttag cagtttttat tggcggtgga acggggagcg tagcccggtg
     3661 gatgctcagt atgcgtttta atccgcttca tcaggcgatt cccatcggta cgctaacagc
     3721 aaatttactt ggcgcgttta ttatcggcat ggggttcgcc tggtttaacc gcatgacaca
     3781 tatcgatccg atgtggaaag tgctcattac gaccggcttt tgcggcggcc tgacgacctt
     3841 ttctactttt tctgccgaag tggtattctt gctgcaagag gggcgctttg gctgggcgct
     3901 gctgaatgtg ctgattaacc tgttgggttc gtttgccatg acggcgctgg cattctggct
     3961 attttccgcc gccgcagcgc gttaagcgca aaaaaaaccc gccgaaaggg cgggttttga
     4021 aatcttgctg tcggacgtat gcttacagag cagttacgtt tgcagcggaa gggcctttgg
     4081 caccgttagt gatttcgaac tctacgcgct gaccttcagc cagagtttta aaaccattgg
     4141 tctggattgc agagaagtgt acaaacacgt ctttgctgcc atcttccgga gtaatgaaac
     4201 cgaatccttt ggattcatta aaccacttaa cgttaccttt aatcttagac atcaaaatta
     4261 cctttacatg aaaaatagac acaaatgctg tatcggatac cagtacaaca attgtgatgc
     4321 attttgtcca gtcgaacttt gcgaaaaagt gataaatatc gcgttaattt ttagctaacc
     4381 ctatctactt attgtttttt aaggcttttt aattcacaac agaacaatgc ccttctccgt
     4441 caaaactgga aacgcatcca ggcaaaatag acgtttccgt tgttatacga acccggaatg
     4501 taggtcatct gaaaggtagc gggaccatag cctatcgacg ctaaaggcaa cagcacaggg
     4561 atgggaatat aattccagtt gtcgcgcgcg gtaacgcctg cggtaaagcc cagtcccaga
     4621 cgaaaattat cgtcttccag cggtcgccag gttttttccc agccataacc gcctatgggt
     4681 tcccatttgt taaatgaatc tttaaaggcc atcatataga ggccatgcca gttgccttta
     4741 tcgtcccagc gcgactgacc aaaaccaacg ccccacggcc gttcgttata gcgatccgtt
     4801 ttctctttat cgtaggcaaa gcgcgcatgc caggtaatgg cggggacata caaatcataa
     4861 tactcaggct gtcgccacgt ttctgcgacg ttatcggtaa acgtgttaaa ccacccttta
     4921 tccgccgcag agactgaagg aatagccagc catggcataa caaggagagc aataataaga
     4981 aaatactttc tgatgatcat cgcaacatac ataccgttca aaaattcgac tgtgataata
     5041 acaacattaa cctgaataaa atcttaacaa actataaaca gagaataatc tgagagagta
     5101 tcgggttaac ggcgtttgat ttagcactca gaaccgtcac gcgctcctta ataagctttc
     5161 acaaaaaaca caaaacaaag cacaacaaat aaaacaataa aataacaata aattaatact
     5221 tatagcgcta cagaaaattt gtataaacat atttcatctt tagtgatgac atgaaaaaat
     5281 aaccgcgccg tgattttaat cagtaaggcg ccatccttta ttcggtacat ttttatacca
     5341 cttttgtggt tcttattttt actctgggtg tcgataagac aggggaaaca atgctaacag
     5401 ttatagagct ccttatcgga gtcgtcgtta ttgtgggtgt agcacgctac atcattaagg
     5461 gatattccgc cactggcgtt ttatttgtcg gcggtctggt tctgcttatt atcagcgcgc
     5521 tgatggggca taaggtatta cctgccagcg aaaccagtac cggctatacc gcaacagata
     5581 ttgttgaata catcaaaatt ttgcttatga gtcgcggcgg cgatcttggc atgatgatca
     5641 tgatgctgtg cggctttgcc gcctatatga cgcatatcgg cgcaaatgat atggtcgtga
     5701 agctggcgtc gaaaccttta cagtatataa actcgcccta cctgttgatg attgccgcct
     5761 attttgtcgc ctgcctgatg tcgctggccg tctcttccgc gacggggctt ggcgtactgc
     5821 tcatggctac tctcttcccg gtgatggtca acgtcggcat tagccgcggc gcggcggcgg
     5881 ctatttgcgc ttcgccggcc gccatcatcc tctcgccaac gtctggcgat gtggttttag
     5941 ccgcaaaagc ggcggagatg ccgttaatcg atttcgcgtt caaaaccacg ctgccgattt
     6001 ccatcgccgc cattatcggt atggcgattg cgcatttttt ctggcaacgc tatctggata
     6061 aaaaagagaa catttcacat gagatgctgg acgtggcgga gattaccacc acggccccgg
     6121 cgttttatgc ccttttgccg ttcacgccca ttatcggcgt actgattttt gacggtaaat
     6181 gggggccgca gttgcacatt attaccattc tggtcatctg tatgctgctg gccgccgtgc
     6241 tggaattcgt gcgcggcttc aacacgcaaa atgtgttttc cggcctggaa gtggcttatc
     6301 gcggcatggc ggatgcgttt gccggcgttg tgatgctgct ggtcgcggcg ggcgttttcg
     6361 cccaggggct gagcaccatt ggctttatcc aaagtctgat ctcgattgcc acttcttttg
     6421 ggtccgccag cattattctg atgctggtct tagtgatttt aaccatgctg gccgcgatga
     6481 ccaccggttc aggcaatgcg cctttttacg cctttgttga gatgatccct aaactggcgc
     6541 actcctccgg tatcaaccca gcctatttat ccatcccaat gctgcaagcc tcaaacctgg
     6601 ggcgcacgat ttcgccggtc tccggcgtcg tggtcgctgt cgccgggatg gctaaaatat
     6661 caccgtttga agtggtgaag cgcacgtccg ttccggtcat cgtcggtctg ttgatcgtca
     6721 ttatcgctac ggaaattatg gtgccaggcg cctcttccgc cgtcaccggc ggctgatagc
     6781 cggtaagccg gggcgaggga aaacatcgct ccggcatctt aaagcgggct tagccgccgt
     6841 gataaatacg ctgcggcctg cccactttgc catgaataat ctctgcgaca atcaggtgcc
     6901 gactcgcgca atattccagg tagcgtcggg atgtggtgcg gcttatcgtt aaggcctgcg
     6961 cgaccgtttc agccgtatgg cgtacggttg gatcggcaaa cagcttcatc accgcattaa
     7021 gggttaaggc atcaatacct gtcggcaaat cccctttcgg ttcgccgcgc gcataggcgt
     7081 tgaacatttc atctatctgc ttctggcttg cgctatccgc gctcgccagc atacgtctgc
     7141 gctgttgata acgggtcagc gtctgcccca aacgctcata agcaataggt ttgaccagat
     7201 aatcaaacgc gccgctacgt accgcttccg ctaccgtctc catgtcactg gcggcggtcg
     7261 taaacacgac gccgccggga tagcgcgact gcattaattc atgcagcagc gtaatcccct
     7321 tcccatccgg cagataatta tccaacagaa ttaatccagg tttgaaccgg tcaatcatca
     7381 ttctcgcctg cgccagattg cccgccagcc atatctggtt aaagccagga atatggcgga
     7441 tatattctgc gtgcatttcc gccagcagcg tttcatcctc aacgatcaat agggttaatg
     7501 gttctgtcat cgtttttttt cactttcgga aggaataaag aaaataaggt gccacaagga
     7561 tcattgtctt ccagcgtaat gaccccgcca cagcgcccca cataacttgc aatcagatat
     7621 aacccgatac catgctcacc gggttcgtca gctcgggtac ttacgccctg ctcaaaaatt
     7681 ttttcccgca gcgcttcagg aacgccgcag ccctggtcgg cgacctctat caccacctcg
     7741 tcgccctcgt cgctcaggaa aagttcgatg gtattgtcgc cttcctgtgt acgtaaactc
     7801 gcctcaaacg cgttatccag cagattcccg acgatggcgg cgaactccgt gctatccagc
     7861 ccctccggca gttgatgtaa ctggctgccg ggaacaatca ccatcttgag ccccagttca
     7921 cgcgcgcgct gaactttgcc aaacagcaaa ccggccacct gacgatcggc gaaggcgccg
     7981 cgtaaactat caataagttg ctgctgcgcc tgcgattcgc cctgcaccat ctctctgacc
     8041 cgatcatact ctttcatttg cagcaggccg ttcagagtcg acatccagtt caggtgctca
     8101 tggcgtagcg tgcgcaggct ctcaacatac tgtttaatct gggttagctg cgcgttcaac
     8161 gtcgcgattt catctttgct gcgaaaacta ataatagcgc ccagcagctc ctcgccggaa
     8221 cggatagcct cacgattggc gatgacgctc aggccattga agttggccat cacgtcctgg
     8281 cgtctttctg cgatctggca ggtaaaaaag tctgccggat tgacgacttc cgctatcagc
     8341 ttgcccagcc actgacgccc cggcgacggc agccccaaca tttttctcgc attgcggtta
     8401 atcgcggtga tatgtccctc cggatcaacg gcgatcagcc cttcataaac cgagctaaat
     8461 aacgcctcct gctggcgtac cacgcgcgca atctgtttcg gctccatgcc cagcatttgt
     8521 cggcggatat gcgcggcgaa aaaccaggaa agcagcatta ataccaccag caacaggaca
     8581 aaaacccccg ccatcggtaa taagaagtcc agccgccagg agtcgatttt actgaccaga
     8641 tagccaattg aaacaacgcc gatcacgttg ccttcgttgt caaagatagg cgttttggcg
     8701 cgcatcgcca tccctattga gcccttaccg gtaatgaaat aactttctcc tctttccagc
     8761 gcgccgggtt tcgtaaactg catgggatag ccgatttttt ccggattcgg atggtaaagc
     8821 cggatcgagt ggcgatcgcc tatcaccaca tagtcaaaat ccgtcccgcg ctgcagttta
     8881 ttcgcaatta tcgccaggcg tttatagtcc cggtttttta cggcagcgat aatgctgtcg
     8941 ttagaagcaa taatttttgc ctgattcatc gccatgtcac gaacatggga cgccagataa
     9001 tcttcgaaac tggcagacaa atattgtgct aacgctgcca cgatgaaaac agaaaccacc
     9061 agaatgagca gaaaaatacg taacggaaac gcgagttgcc gaaaaaaagg aaacagcttt
     9121 ttatttttct gataggacat taaggttcct tatgggtatt tctctacaga tttatcgcaa
     9181 atgtaataaa aatgttttga gtatcttgaa gcatataaaa accaatcgtt acagattccc
     9241 cacattaaat caattaaaca actaaaaccc actgccggaa tggcgattaa attaattaaa
     9301 aaacttaaaa ccataaaaca cttaaaaacc atctaacgct ttgtgaaata aatcaaaatt
     9361 taccaccaaa atactcctta cgatgtatac gtcagagaga aaaataaata actcgtcata
     9421 aaaatactcc cactctgact gaaaagaaaa agttatcaag ttgcaacaca acgcaacata
     9481 tacagaaaag tggcaacaag catatcacca ggatatttct tactatgttt ggcaataatg
     9541 tattcactcg ggtaaaacgc tctgaaaata aaaaatggcg gagatcgctc actttctcaa
     9601 agagaatgat ttaagcgtcg ataccactgt agaagtgttt attaccgtca gccgtgatga
     9661 ccgtcttatt gcctgcggcg gtattgccgg aaatatcatt aaatgcgtgg ccattagcga
     9721 atcagtacgc ggtgaaggct tagcgttaac gctggcgacg gaattgatta atctcgcctg
     9781 ggaacggcac tgcacccatc tttttattta taccaaaacg gaatacgaag cgctgtttaa
     9841 acagtgcagc ttttcgacga tagccagcgt ccctggcgtg atggtcttaa tggaaaatag
     9901 cgcgacccgg ttgaaacggt atgcggaatc gctggcgaca ttgcgtcacg agggaaagaa
     9961 aattggctgt attgtgatga acgccaatcc tttcacgcac ggccatcgct atctgatcca
    10021 acaggcggcg gcacagtgcg actggctgca tctgttcctg gtcaaagaag atacgtcacg
    10081 ctttccctat gaagaccgac tcgatctggt ccttaaaggg actaccgata tcccgcgctt
    10141 aaccgttcat cgcggctccg aatacattat ttctcgtgcg acgttcccct gctatttcat
    10201 taaagagcag agcgtcatta atcactgtta taccgaaatc gacctgaaga ttttccgcca
    10261 gtatctggcg cccgcgcttg gcatcacaca ccgctttgtc ggtacggagc cgttttgtac
    10321 cgttaccgcc cagtacaacc ttgatatgcg tttctggctg gagacgccaa cgcttcccgc
    10381 cccacccatt acgctggtgg aaatagagcg gctttgcttc caggagacgc cgatatccgc
    10441 ctcctgggta cgcaagctgc tggttaaaca cgatctcacg gctatcgcgc cgctggttcc
    10501 cgacgccacc ctgcgctatt tgcagggcat ggtcgaacgc catccgggca gcgcggcagc
    10561 ccgtcaaaag tcccccgtat tagcaacagg tgaaaaatga aaataaacca gctagccgtc
    10621 gcaggcacgc ttgagtccgg cgatgtgatg atacgcattg cgccgctcga tacgcaggat
    10681 attgacctgc aaattaacag tagcgttgaa aaacagtttg gcgaggccat tcgcgccacc
    10741 atcctggagg tgctttctcg ctacgacgtg cgcggcgtac aactgaacgt cgatgataaa
    10801 ggcgctctgg actgcatttt gcgcgcccga ctggaaacgc tactggcgcg cgccagcggt
    10861 attgccgctc tgccctggga ggatcgccaa tgatttccgc ctctctgcaa caacgtaaaa
    10921 cccgcacccg ccgcagtatg ttattcgtac cgggcgccaa cgcggcgatg gtgaacaatt
    10981 cgtttatcta cccggccgac gcgctgatgt tcgacctgga agactccgtt gcattacgcg
    11041 aaaaagacgc ggcgcgccgt ctggtatatc acgcgctgca acatccgctt taccgtgacg
    11101 tcgaaaccat cgtccgcgtg aatgcgctgg actccgaatg gggcgtcaac gatctggaag
    11161 cggtcgtgcg cggcggcgcg gacgtggtgc gtttaccgaa aaccgacacc gcgcaggacg
    11221 tcattgatat cgaaaacgaa attctgcgca ttgaaaacgc ctgcggtcgc gaaccgggca
    11281 gtaccggcct gttagccgcc gtggaatcgc cgctgggtat tacccgcgcg gtagaaatcg
    11341 cccacgcctc tgaacggttg atcgggattg cgctgggcgc ggaagactat gttcgcaacc
    11401 tgcgcaccga acgctctccg gaaggcaccg aactgctgtt cgcccgctgc gccattttgc
    11461 aggccgcgcg ttccgccggc attcaggcct tcgataccgt ctattccgac gccaacaacg
    11521 aagccggttt cctgcaagaa gccgcccaca ttaaacagtt gggctttgac ggtaagtcac
    11581 tgatcaaccc ccgccagata gaactgctgc acaaccttta tgcgccgacg cgtaaagagg
    11641 tcgcccatgc gcgtctggtc gttgaggccg cagaagccgc cgcccgcgaa ggtctcggcg
    11701 tcgtttccct taacggcaag atggtcgaca gcccggtgat tgaacgcgcc cgtctggtgc
    11761 tctcccgtgc agaactttcc ggtattcgcg aagaataagg caaaaaaatg acgcagaaaa
    11821 atgaatctca acgccaggat cgcgtagtag cctggagccg tcacgctgaa agcgaactga
    11881 gcgcttacca aagtgcggca aaattggatc tacaagcgca aaaaccgcgc gaccacaaac
    11941 tgtgcgccag cctggaagag gccatccgcc gttccggttt acgcgacggc atgacgcttt
    12001 cctttcacca cgcttttcgc ggcggcgatc tgacgattaa cctggtgatg gaaaccatcg
    12061 cgaagatggg cttcaaaaat ctgaccctgg cctccagctc gctgagcgac tgccacgcgc
    12121 cgctggttga acacattcgt aacggggtgg tcagccgcat ctacacgtca ggcctgcgcg
    12181 gcccgctggc ggaagaaatt tctcgcggcc tgctggctga gccggttcag attcactccc
    12241 acggcggtcg tgtgcatctg gtacaaagcg gcgaactcaa tattgatgtt gcgtttcttg
    12301 gcgtgccctc ctgcgatgaa ttcggtaatg ctaacggtta taccggcaaa gcctgttgcg
    12361 gttctctggg ctacgcgatg gtggatgccg acagcgcgaa gcaggtcgtg atgctgacgg
    12421 agcaactgct gccgtatccg cataacccgg caagcatcgc tcaggatcag gttgatctga
    12481 tcgtgcaaat cgaagaagtc ggtgatgcaa acaaaatcgg cgctggcgcg acccgcatga
    12541 ccactaatcc gcgtgaactg ctgatcgccc gcagcgcggc ggaagtcatt gctcactccg
    12601 gctacttcaa cgaaggtttc tccctgcaaa ccggcaccgg cggcgcatcg ctggcggtca
    12661 cccgcttcct ggaagacaaa atgcgtagcc gcaacattgt ggctaatttc gcgctgggcg
    12721 gtatcaccgc caccatggtc aacctgcatg aaaagggctt aatccgcaaa ctgcttgacg
    12781 tgcagagctt cgatcgtaac gctgcgcaat ctttggcccg caacccgaac catatcgaaa
    12841 tcagcgctaa ccagtacgcc aactggggct ctaaaggcgc ttccgtcgac cgtctggacg
    12901 tggtggtact gagcgcgctg gaagtagaca cccacttcaa tgttaacgtg ctgaccggct
    12961 ccgacggcgt tctacgcggc gcgtccggcg gtcactgcga taccgccgtc gcggcggcgc
    13021 tgtccatcat cgtcgcgccg ctggtgcgcg gtcgcatccc aacgctggtt gataacgtca
    13081 ccacctgcgt cacaccgggc tccagcgttg acattctggt caccgatcac ggtatcgccg
    13141 tcaatccggc gcgtccggag ttggctgaac gcctgaaagc agcgggaatg aaagtggtat
    13201 cgattgagtg gctgcgcgaa cgcgcgcaac tgcttaccgg tcagccccgc cctatcgaat
    13261 tcaccgaccg cgtgattgct gtcgtgcgtt atcgcgacgg ttcagtgatc gatgtggtgc
    13321 atcaggtgaa ggaataagcc acgccactcc actggtctcc tttaccgtgg tggcgccagg
    13381 cccgatgaaa gacagcgcgt taacccgccg gatctttaat cacggcgtga ctgccctgca
    13441 cacgctggca gaagagtatg gctggaccat ccgggagcag gctgcactgg cttccgccag
    13501 cgggccggaa gggttgctgg cgattgacgc gcccgctcag gcgctcaaac aggcgaccat
    13561 cgcgctggaa cagcgttatc cactggggcg cctgtgggat atcgatgtcc tgacggcgga
    13621 aggcgaaata ctctctcgcc gccatttcgc gcttcccgct cgccgctgtc tgctgtgcgg
    13681 gcaaagcgcg gctgaatgcg cgcggggtaa aacccacgcg ctgactgatt tactgactca
    13741 tatggaggcg ctgctgcatg atgccgattc ccgtcaaccc gactaacgcc tccattcagc
    13801 ctcagtcgct gtatgacgcc tgggccgatt tggcctggcg cgccatgctg accgaggtaa
    13861 atttatcgcc aaaacccggt ctggtagacc gactaaactg cggcgcgcac aaagatatgg
    13921 cgctggcgga ttttcaccgc agcgcggagg cgattcgaca ctggctgccg cgctttatgg
    13981 aatatggcgc cagctgcacg cgcctgccac cagagtcagt tctggcgggc ctgcgtccat
    14041 tggggatggc ctgtgaagca gcgatgtttc gcgcaacggc gggcgtcaat acccataaag
    14101 gcagcatttt ctcgctgggg ttactgtgcg ccgccattgg ccgcctgtat cagctacgcc
    14161 agccgatcgc cgcagaaaca ctctgcgcta ccgccgccga tttttgccgc ggcctgacca
    14221 cgcgcgaact gcgccagaac aacctacagc tcaccgcagg ccagcggctg tatcagcaac
    14281 tgggattaac cggcgcgcgc ggtgaagcgg aagcgggcta tccgctggtc atccgccacg
    14341 cgttgccgca ctaccgcgca ttgctggcgc aggggcgcga tccggaactg gcgctgcttg
    14401 ataccttact gctgctgatg tcgcttaacg gcgataccaa cgtcgcttcg cgcggcgggg
    14461 cggacggtct gcgctggtta cagcagcagg cggcggtctt attacatcag ggcggcatac
    14521 ggacgcctga tgatctcgtt tatctccacc ggttcgatca gcaatgcatt gaacgcaatc
    14581 tcagcccagg cggtagcgcc gatctgctga tcgtgacctg gtttttagcg caaatttcgc
    14641 aagttaatca ttaacacaat tatagaaaat atcctttccg gagagtcatt tatgtcttta
    14701 tccaaagata atatatggaa gttgttggcc ccattagtgg tgatgggcgt catgttgcta
    14761 attcctgttc cagatggtat gccgccgcag gcctggcact attttgcggt tttcgtcgcg
    14821 atgattgtcg gtatgatcct ggagccgatc ccggcgacag cgatcagttt tatcgccgta
    14881 accatttgcg ttatcggcag caattacctg ctatttgacg cttcagaact ggccgatccg
    14941 gcgtttaaag ccagtaaaca ggcgctgaaa tgggggcttg ccggtttctc cagcaccacg
    15001 gtctggctgg ttttcggcgc gtttattttc gcgctgggct acgaagtgac cggactgggg
    15061 cgccgcattg cgctgtttct ggtaaaattc atgggtaaac gcacgctgac gctcggctat
    15121 gcgattgtca ttatcgatat tttgctggcg ccgtttactc cctccaatac ggctcgtacc
    15181 ggcgggactg tcttcccggt tatcaagaac ctgccgccgc tgtttaaatc gtttccaaac
    15241 gatccttccg cacgccgcat cggcggttat ttgatgtgga tgatggtgat cagtaccagc
    15301 ctgagctctt cgatgtttgt cactggcgcg gcgccaaacg tgttaggtct ggagttcgtc
    15361 agcaagatcg ccggggtcca gattagctgg ctgcagtggt ttctcagctt tctgccggta
    15421 gggattattt tactgatcgt tgcgccgtgg ctctcctatg tgctttataa acctgaagtg
    15481 acccacagtg cggaagtcgc ggcctgggct ggcggcgagt taaaaaacat ggggcgtctg
    15541 tcccgcaaag agtggacgct gattggcctg gtgctgctta gcttaggatt gtgggttttt
    15601 ggtggaaaaa tcatcaacgc cactgccgtg ggtctgctgg ccgtctcgct gatgctggcg
    15661 ctgcatgttg tgccgtggaa agatattacg cgctacaaca gcgcctggaa caccctggtg
    15721 aacctcgcta cgctggtggt catggccaat ggcttaaccc gctccggctt tattgactgg
    15781 ttcgccaata ccatgagtac gcatctggaa ggtttctcgc cggatgcaac cgtcattgta
    15841 ctggtactgg tactggtact ggtactggta ctggtactgg tactggtact ggtactggta
    15901 ctggtactgg tactggtact ggtactggta ttctatttcg cgcactattt gttcgccagt
    15961 ctttccgctc acaccgcgac catgctgccg gtcattctgg cggtgggtaa aggcattccg
    16021 ggcgttccga tggaacaact gtgtattctg ctggtgctgt ctatcggtat catgggctgt
    16081 ctgacgccgt atgccaccgg ccctggtgtg attatctacg gctgcggtta cgtgaaatcc
    16141 agagactact ggcggcttgg cgcaatcttt ggcgttatct atatcgcaat gctgttgctg
    16201 gtgggctggc cgattctggc aatgtggaat taaacattac gccaacgtag gttaaaaatg
    16261 atgccgttca ggttcacctg agcggcattt tttatgatta aatgagtaac attcataatg
    16321 tctataaatt atcgaattca tcatgaacac aatatggcat tacagtccgc tgctggctgt
    16381 cctcttaacc ccgatttttg ccgccaacgc cgacgaactt caggcgcaac agtacggtga
    16441 tttcactgac tatgtgctgg cgctttcctg gcaaaccggt ttttgtcaaa gccagcatga
    16501 acgccgccat cgggaacccg atgagtgccg tctgcaaaaa gagccagcca acaaagcaga
    16561 ctttctgacc gtccacggcc tgtggccagg attacccaaa tctatcgccg cacgcggtgt
    16621 tgaccagaga cgctggcagc gctttggttg tgcgacgcgg ccaatcccga atctgcctga
    16681 agtcaaggcc agccggaaat gctccgcccc cgcccccgga ctttcgcctg acatcgcgac
    16741 agcgcttaag gaagtgatgc ccggcgcggg ggggaattcc tgtctggagc gctacgaata
    16801 tgccaaacat ggcgcctgtt tcgggtttga tcccaatgcc tatttcggca ccatgatacg
    16861 gctggataag gcgataaaag acagcgcgct ggggcagttt ctggcggata attacggcaa
    16921 gaccgttagc cgcgctgagt ttgatagcgt cgtcgcacaa acgtggggcc aggataatgt
    16981 caaagccgtt aaagtaaact gccatggcaa tcccgcctat ttaacagaga ttcagttttc
    17041 attaaaggcg tcgatgatta acgccccgct ctcctctgcc tcattccagc cgcagccgca
    17101 tcccggcaac tgcgggaaac agtttattat cgataaagcc ggttattgac gaagcagagg
    17161 tttaaaaccg tagccacatt tgagaacacg cccgaatgta gactaaaatt cactcagggc
    17221 tatgacgttt gaggatttac ccgaatgtga actaaatcac ttcaaagacg gggtaagtct
    17281 cagtatcatc atgagagtta aaccctcgcc gccagacggt gagggttttc ttttgggacc
    17341 atttacctgc actactcgca gtatcgatga catggagtaa gaaatgtcca gacccactat
    17401 tatcattaac gaccttgacg ccgaacgtat tgatcgtctt ctggaacagc ctgcgtatgc
    17461 ggatctgccg attgccgacg cgctcaacgc cgaactggat cgcgcgcaaa tgtgttcgcc
    17521 acaagagatg ccgaacgatg tcgtcaccat gaacagccgc gttaaattcc gcaatttgag
    17581 cgatggtgaa acacgcgtgc ggacgctggt gtaccccgcc aatatgacgg acagcagtac
    17641 ccagctttcg gtaatggcgc ccgtcggcgc ggcgttgctg ggactgcgcg tcggcgacac
    17701 cattcactgg gaactgccgg gcggcgcctc cacccatctc gaagtgctgg aactcgaata
    17761 tcagcctgaa gccgcgggcg acttcctgcg ttaaaccatc tgcataagcg ttaatgcgtt
    17821 tacacagagg atgcctgcgc atcctctttc cgttagctct ttcatttctg cctgcttcag
    17881 acaacgccgc ctggcatcgg gttgattact cccgtcgcct gtttctgcgc cgcttgtgcc
    17941 gacatcgctc ccggcaccag gataaccttc cggcactctt cttcgcgttt ttcgaaaatt
    18001 tcgtagccgc gcgccgcctc ttcaaacggc atatagtgcg tgacaatctc ctccggcttc
    18061 agcaaccctt tttcaataag cggtaataat tcccccagcc acgcgtgaac atgggtttga
    18121 cccattttaa aagttagccc cttatcaaag gcgtcgccga ataaaaagcc gtgaataaaa
    18181 ccggcataca cgccgggcac gctgaccacg ccgccgcgtc ctaccgccgc gatacattgt
    18241 cgcagcgctt tgccgctgct gccttccagt ttaaggttcg tcagcaccgt ctccgtcatg
    18301 ctgcctttcg cttcaaagcc tacggcatca attaccgcgt ccacgccgcg gtgtcctgcc
    18361 gtctgctcga tgattttttc cgccggatcg ttctcatcat cgaagttgat cggtatcgcg
    18421 ccgtaacgtt cttcggcgaa acgcaggcgc caggcgtggt gatcaacgac gaagatctgc
    18481 tccgcgccca gcagtcgcgc acaggcgata gtcagtaatc ctaccggccc tgcgccaaaa
    18541 accgccacgc tggaacgttg ctgaatctgg gcattttttg ccgcctgcca ggcggtaggc
    18601 aaaatatcag aaagaaacag cgctttatcg tcagataaca gcggcggcac cttaaatgga
    18661 ccgacattac cttttggcac gcgaacatat tcggcctgtc cgccgggaac gccgccatac
    18721 agatggctat aaccaaacag cgccgccggc ggcgggatct gttttttatt catcgccgcg
    18781 ccgtgtccgt cgttagtgtt ttcacacgct gaatattgct gtagtcgaca gaaaaagcag
    18841 tcgccacaag caatgacgaa cgggataaca acccgatccc ctttccgaat attcttcaca
    18901 tcatgtccgg tttccaccac ctcgcccata aattcatggc cgaaaatatc accatgtttt
    18961 acctgtggga tcttgccgcg atagagatgc aaatcagatc cgcaaatcgc ggtggcggta
    19021 acacgcaaaa tgatatcgtc aggctgctca atgccgggat cgggtacgtt ttcaaccttt
    19081 acgtgatgtg gaccgtgata cgtcaatgct ttcatgcagc ctccggggta acggtgaatg
    19141 ttgcgttcga ctataaaagg gtagctatcc cggagagact accggaaaaa caggcggctt
    19201 taggattttt cctggaaaat acacgacttt tttaacgtca ggttgtcgca atatttaaaa
    19261 ttgccagaca aatagcagaa agaaacatta ttatatgctt gaataaattc agtattgatt
    19321 aacagggagt aacgggtatg tataagacaa tcattatgcc ggttgatgtt tttgaaatgg
    19381 aacttagcga taaagccatt cgccacgctg agtttctggc gcaacaggat ggcgtcattc
    19441 atctgttgca tgtactgcct gggtccgcga gcatgagtct gcaccgcttt gccgccgacg
    19501 tgcgtcgctt tgaagaacat ttacagcatg aggcggaaac gcgtctgcaa acgatggtgg
    19561 gacacttcag tatcgatcct tcacgaatta aaacgcatgt tcgctttggt agcgtgcgcg
    19621 atgtcgtcaa tgagatgggc gaagaactgg atgcggatgt cgtggtaatc ggttcgcgta
    19681 atccgtctat cacgacacac ctgttggggt ctaacgcctc aagcgtggtg cgccatgcga
    19741 cgctgccagt attggttgtg cgttaaccct ggtggctaaa aactgacacg ccctgccagg
    19801 tcacgcctgg cagggctttt tactgcatca tcgttagtac aaatgcccga tattcacaat
    19861 agtactcacc gtgtcgccaa aaaagaccag ccgactcaga aatacgccaa cgaataacaa
    19921 gacgaacagg agtttcgggc gcgaatcacc gtgacggctg gcgacaaaag cgagcgcaag
    19981 gcaaaccagg cttgccagat aaaacgggga agccagccat gaacgcgccg tcatctgcat
    20041 gaccgttccc ccgcttaacc acaccagcgg cgccgcgata agtaccgcga tacacaccac
    20101 aattccctgg cgtaacgcag gaacggcagg cctgagtctt aacagcggaa tcgccgcgca
    20161 acccatgacc cataccgtaa taaaaaataa cagcatggta aatccattag cgatagctac
    20221 catcgctggc gcggcgtagg tcatcccctg caccgccacc agtaacacgc cgaacacgga
    20281 ggcgataaga gccatcgctt tatgtccctt tgccaggaac gttacgccga ccgctgcgcc
    20341 aaacaacgtg gcgccaagga tttcccgact taaccaggca tgtcgcaggt taatcagcgc
    20401 attataagcg cgatcgggat gcgccagatg cagaatcgcg gcaatagacg ccaatgccag
    20461 caccagcccg gtggccaacc aatagaaacg ctggccttcc acttcaccac gcagcgtacg
    20521 ccatgtcagt accaaagcca tcccgacaga catctggctt aataccgtaa aaaacaccag
    20581 cggcagttca tatttttcca ttacttgtcc tccggctgct taggctggcg cgccagaata
    20641 aagcgcgttc ctggattgag ctgtggcata tgcgggaacc ctggcggata ctgcaccgca
    20701 ttatcgggca caggatcggc atccaaatcg ataatcgaca aggcgcccac cggacaggcg
    20761 ttcacgcacg ccggattcat accgatatca agacgctcgt agcatatact gcatttttcc
    20821 gctttacgcg tctcttcatt aaaacgcggc gcgccataag gacagttacg aatacagttt
    20881 ttacagccga tgcagcgctc agggttatgc accaccacgc catcttcacg tttggtatag
    20941 gcttcgaccg gacaggcggc gacgcaggcc ggatgttcgc agtggttaca ggccagcgag
    21001 taaaacgccc gctcttcatg tggatagatg tctttatcca acggataaac gtagcgccag
    21061 aagcgatccg gctccagttg gttaaagctt ttacacgcca tagcacagcc gcggcagccg
    21121 atgcacttat cgctattcac taaaaacgca cgtctcatgc tacggattcc cctttaccga
    21181 tcaatacaac gtcagcaaac tgactgtgga tagcggcgcc cggcgcgcca gttttcatca
    21241 gccccatatc agcaggcgta tcggccacga cgttttgcac gttgtactgc cgtttcggga
    21301 accacgcttc atacatcacc agaaaatctt ccggcacgtt ggtggtgact tttgcccgca
    21361 gttccacctc gccaatgttg ttgaaaactt tgacccggtc attttcgcta atgccttttt
    21421 tcttcgcgga agaaggatgg atataaacaa acggttccgg atagaacacc tgcatccagt
    21481 ccaggttgat aaactgcgag tgcaggccaa actgcacgtg cggcgtaaac agatggaaag
    21541 gcagtttgct ctcggcttcc ggtttgtatt ccggcagcgc ggtgtggccg tttttctccg
    21601 ccagttcaga tttaaattca tacttgcctg acggcgtttt gaacttgcga tcgtaccagg
    21661 cggcagagct tggcaggatc gctttttttg gcccgtccag cagatcgtcc caggaagaga
    21721 tgccgaacat tttcgccata ccgtcgttga actcctgatc cagccagcgc ttgtgatcga
    21781 actcttgcgg gaaggtacag gaacccggcg ccatcttatt aatggtgcgc gacagcatgg
    21841 tagcgatttc aaggtcgcat tttgcttcat acatcggctt aatcgccggc tgattaatgg
    21901 aaagccagta gtgccagtaa gaagcatcca cgttccactc ttcaaacgcg gtggtaacgg
    21961 gcagcacgat atcagcgtgt tgcaccgttt cgttgaagaa ctgatcggcg cagaccacca
    22021 tttccagttt ttcaaacgct tttttcatct tgctgcgatc gaaatcctgg gcaaacgggt
    22081 ttttacaggc gacccacagc atacgaaccg gcggatcgtt ggcctccaga atcccctgcg
    22141 ccgtctggtt aatattcaga gagcgatcgg agtactgcac ggcgtcgctg ccagcggcag
    22201 ccccgaattc actggtggtg cccgccgctc ccggtatgcc aatagcgccc accggcggct
    22261 tctgcagcat ggcgttatag ttaaagcccc aggtatgcag atggccataa cgcgcgccgc
    22321 cgccttcgac accgatgttg ccggacatag cgacaaaggc atcgatagcg cgaacgttgg
    22381 cgccgccgtt gacatgacgc tgcatcccgt aaccaatcca ggccgtggcc gggttaaccg
    22441 ccgtaaactc ttccgccagt tgacgaatca cctgtgccga caacccgcag atttctgccg
    22501 cccactccac ggttacatgg ttacgcagat aggcttcaaa ttccggatag ccatgagcgt
    22561 cgttgttgac aaaatcctga tccaccaggc ccttatccac cagatggcgc gccatcccca
    22621 gcgccagcgc gccgtctgag ccaggccgta cgcgcaggta gagatcggct ttggcggcag
    22681 tctgcgacag cagcgggtcg ataaccacga ccttcgcccc tttctcgcgc gcctgataga
    22741 tatatttcat ggagtgcatt gagcaccagg ctgggttcgc gccccagata atgatgtatt
    22801 ttgctttcac catatcttcc gggtcgttac accacatgtc acccatgtcg tagttttgcg
    22861 cgtcaatacc ggcaggccag cacggcgtac cggcaaaacg ggtggtatag ccaagcgagg
    22921 acatcatccc ttcaacggca tagttcagca cgccaaactt accggaatat ttggtcagcg
    22981 ccagaccgag catagaactg tcttttttct taatctccag cattttggcg gcaatacgct
    23041 gcatcgcctc ttcccatgag atgcgacgcc agttgccgct accgcgaacg tcctgcgcca
    23101 tgggatattt aatacgatcg ggactataaa cccggcgcgg atagctcaac cctttgacgt
    23161 aaggcgtacc gtgagtaaat gttgattccg gcgcaccttc cacgaaagta atgaccccgt
    23221 cctttaccca cgtcttgagg ctacaggtgt catagcagtt acgcggacac gcgttacgat
    23281 aaattttgta cgttttaggg ttaaagggaa caggcggctg cgcaagcgcg catcgggagg
    23341 tcagtaatcc tccgggtaaa gccgcaacgg tgcccagcgc cactatcccc tttaaaaaag
    23401 aacgtctgtt cagatgtccc gtctcattac tcatattgat actctcgttt taattcatca
    23461 aaccaataaa ataagatgtc cgccaccgta tataacgtgg tcgtttatgc atgagttttt
    23521 attttttcga tatataatgg cacccacttt gttaaatagt tattgatata ttgagtgagg
    23581 gtagagcagt attgtgacgt ttgccgggta ttagccagta atagtgtggt caattccagc
    23641 acgcaggaaa tatgatcgtc aggaatattg ctttcctgat taaccgataa tcccaacgct
    23701 gccataaaat cccgtatctc cagcgtcgcc tttcccatca ccagcgcatc ctcttccaga
    23761 tacactgaag cgaaaggcgc agccagcagc ttgccagggc cgacgaatag cgcattaaag
    23821 tcatactccg cttccagcca cgcccggtcg gtaaggttta ccgcagcaga tggatttaat
    23881 ctcacgtagg cagatttcag tgaatgacta tcatgagaat taaaaaaatc acgcaatgta
    23941 agccctgttt tttctaattc cgtcagtgat tcatagattg aatccatgaa taaataacct
    24001 cacatacaaa tgcaatataa atcaagaaaa aagaatgggc atgttaacgg aagcgcttaa
    24061 tctttctttg ataaaaaaac agaaaaattc cagttaaatc cgtagaagac ttttttattg
    24121 tttcaaagtt taaaaacaga agaccgttg
//
LOCUS       DAJVKX010000059        24130 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000059 DAJVKX010000000
VERSION     DAJVKX010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24130
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.059"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(221..1765)
                     /gene="cadC"
                     /locus_tag="OPY25_002477"
     CDS             complement(221..1765)
                     /gene="cadC"
                     /locus_tag="OPY25_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HCS0928073.1"
                     /translation="MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHP
                     DEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLRDGGDSNAEYIVTVPKRGYKLTA
                     PVIWCEENSDEIDNLSTSPPPPIAATNAEPTEGVPAAAPVPPASLQTPTKKAKKPRIA
                     AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQ
                     ESYAIGLGGLITDLLNTYSTFMVHDKTNYRVNEPSNSGKTLTIQFVNQRHYRAQQCFM
                     SVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPWPNRMREQLALFRTP
                     QNTALMRFYEARQLILSGDAQALSKAGDILNGIIKETPDFNYAYEYKVLVDVLRQSQQ
                     PFDKEQVAALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEM
                     SWFNYVLLGKVYEMKGENRLAADAYLTAFNLRPGENTLYWIENGVFQTSVQKIVPYLN
                     SFLAED"
     gene            complement(1946..3136)
                     /gene="hmpA"
                     /locus_tag="OPY25_002478"
     CDS             complement(1946..3136)
                     /gene="hmpA"
                     /locus_tag="OPY25_002478"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HCS0928074.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGTHL
                     LATLDEMFNPGQEVLDAWGKAYGVLANVFIHREAEIYHENASKDGGWEGTRPFRIVAK
                     TPRSALITSFEFEPVDGGTVAEYRPGQYLGVWLKPEGFAHQEIRQYSLTRKPDGKGYR
                     IAVKREDGGQVSNWLHHHANVGDVVHLAAPAGDFFMNVAADTPVSLISAGVGQTPMLA
                     MLDTLAKEQHTAQVNWFHAAENGDVHAFADEVSELGRTLPRFTAHTWYREPTEADRAQ
                     RVFDSEGLMDLSKLEAAISDPAMQFYLCGPVGFMQFAAKQLVSLGVNNENIHYECFGP
                     HKVL"
     gene            3461..4714
                     /locus_tag="OPY25_002479"
     CDS             3461..4714
                     /locus_tag="OPY25_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCS0928075.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIVPYGIDESGKIDYDEMAK
                     LAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGDEELYKKLNSAVFPSAQGGPLMHVIAGKAVAL
                     KEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDVLDN
                     INDEATIERVKAKVLDICARFPVYA"
     gene            4899..6038
                     /locus_tag="OPY25_002480"
     CDS             4899..6038
                     /locus_tag="OPY25_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HCS0928076.1"
                     /translation="MALHSTRWLALSYFTYFFSYGIFLPFWSVWLKGLGLTPETIGLL
                     LGVGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLVFALAFWAGTHVAWLMVVMVG
                     FNLFFSPLVPLTDALANTWQKQITLDYGRVRLWGSIAFVIGSALTGKLVSLYDYQAIL
                     ALLTLGVASMLLGMLLRPSVPPQGESRQQESAGWPAWRTLVAQSWRFLACVCLLQGAH
                     AAYYGFSAIYCQGAGYSASAVGYLWSLGVVAEVIIFALSKKLFRRFSARDLLLLSAVC
                     GVVRWGLMGWSTALPWLIVIQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQHLGGGVFWIMALVALPAIFLRPKVVAAS"
     gene            complement(6033..7310)
                     /gene="csiE"
                     /locus_tag="OPY25_002481"
     CDS             complement(6033..7310)
                     /gene="csiE"
                     /locus_tag="OPY25_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HCS0928077.1"
                     /translation="MMPTIAPPSVLSAPQRRCQVLLTLFQPEPIATVEIFSALNGVDD
                     DTAREDITDTSLEIQRYHRLAITTCQNGCYRIEGTALDQRLCLLHWLRRGLRLCPTFV
                     TQQFTPALKNALKQRGIARPLYDDINLHALINLCARRLQKPFEHRDVQFLRLFLQYCL
                     LQHHAGITPEFNPVQQIWAQSCAEYPLAQEIGRHWQRHVMQAAPLNEALFMALLFSMI
                     RLPDPIRDTHQRAQQLRLEVARLVLRFREKGNVRFSDEQGLNDQLYVHLAQALNRSLF
                     TIGIDNTLPEEFNRLYPRLVRTTREALAGFEAEYGIHFSEEETGLVAVIFGAWLMQDN
                     DLHERQIVLLADKNDALETHIEQQLRELTLLPLNIRRISLQAFQKEGCPRGVALIVTP
                     YATPLPLFSPPLIHADRALTEHQQQQIRKILES"
     gene            7436..8074
                     /locus_tag="OPY25_002482"
     CDS             7436..8074
                     /locus_tag="OPY25_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1007 family protein"
                     /protein_id="HCS0928078.1"
                     /translation="MKPVKRSALILFLAVLSFVAAAHPHSFIRLQTQVVSENEQFVAL
                     KMRWTMDALTSADLLYDAGNAAPGSEIWKKLAAEVMANVLGQHYFTEVWRNGAKVKFK
                     NRPTEYGMTRDAHQAVLTFTLPLAEPQPLSGQTYTFSTFDPSYYVDMHYDQDSDITMP
                     EPLREKCRIQVYTPAPGEETLRFAQSLDKEDAPPEDMDLGKQFAQTVTLQCQ"
     gene            8065..9050
                     /locus_tag="OPY25_002483"
                     /pseudo
     CDS             8065..9050
                     /locus_tag="OPY25_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461486.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt transporter"
     gene            complement(9051..10064)
                     /gene="asrC"
                     /locus_tag="OPY25_002484"
     CDS             complement(9051..10064)
                     /gene="asrC"
                     /locus_tag="OPY25_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HCS0928079.1"
                     /translation="MSIDIDIIKARAKNEYRLSKVRGEAMISVRIPGGILPAHLLTVA
                     RDIAETWGNGQIHLTTRQKLAMPGIRYEDIDNVNAALEPFLREIEIELCDVQVEDTKA
                     GYLAIGGRNIVACQGNRICQKANTDTTGLSRRLEKLVYPSPYHLKTVIVGCPNDCAKA
                     SMADLGIIGVAKMRFTADRCIGCGACVKACSHHAVGCLALKNGKAVKEESACIGCGEC
                     VLACPTLAWQRKPDQLWQVRLGGRTSKKTPRVGKLFLNWVTEDVIKQVIVNLYEFEKE
                     MLGGKPIYLHMGHLIDKGGYLRFKERVLRGVQLNPEAMVAERIYWAEDESVARMHLKP
                     AGH"
     gene            complement(10075..10893)
                     /gene="asrB"
                     /locus_tag="OPY25_002485"
     CDS             complement(10075..10893)
                     /gene="asrB"
                     /locus_tag="OPY25_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit B"
                     /protein_id="HCS0928080.1"
                     /translation="MSHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHW
                     GQFVEVSLPRVGEAPISVSDYGDGWIDLLIRNVGKVTSALFTLKEGDNVWLRGCYGNG
                     YPVDTLRHKPLLVVAGGTGVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEM
                     ATWHGKHNLVLTLDEGEADDRYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVK
                     MLLQKGLKPEQIWVDYERRMACSVGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD"
     gene            complement(10897..11940)
                     /gene="asrA"
                     /locus_tag="OPY25_002486"
     CDS             complement(10897..11940)
                     /gene="asrA"
                     /locus_tag="OPY25_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit A"
                     /protein_id="HCS0928081.1"
                     /translation="MAIKITPDEFSLLIQRLNKKWRVFAPSAEFRGGRFSDTDNIIYQ
                     RISGWRDLIWHEKSHMSPNTIIAPITETLFYFDKNTIQIAETDTSPIIIFARACDINA
                     MSRLDYMYLSNGNNSDYSYQLLREHIRFVLIECEESFENCFCVSMGTNKTDCYSAAMR
                     FSDEGALVSIRDPFIEAAIQGLGQEADYTPSFVSENRETVVTPDSVCRDPQKIRDILT
                     RHPLWDAYDSRCISCGRCTTGCPTCTCYSVFDVAYDENPQRGERRRQWASCMVPGFSD
                     MAGGHGFREKPGERLRYRALHKVNDYKARNGIEHMCVGCGRCDDRCPQYIKFSLIINK
                     MTAAVRQALAEEA"
     gene            complement(12122..13000)
                     /locus_tag="OPY25_002487"
     CDS             complement(12122..13000)
                     /locus_tag="OPY25_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCS0928082.1"
                     /translation="MTLQHTRRIVKSLFILFIIVVCIYLLPRVAINAFYYPDNKVYGP
                     TPAEAESITFTAKDGTHLHGWFIPTAFGRPENAVATVIHVHGNAGNMSAHWPLVSWLP
                     ERNVNLFMFDYRGFGESEGTPSQEGLLNDTKSAIDYVRHRADVNPERLVLLGQSLGGN
                     NVLAAVGHCVGCANMRYADQAGIRAIVLDSTFSSYSSIANQMIPGSGYLLDDRYSADR
                     NIASVSPIPVLILHGTADHVIPWQDSEKLYALAREPKQKIFIPDGDHIDAFSGRYANL
                     YRDAMINFIQTALSAK"
     gene            complement(13145..13948)
                     /gene="suhB"
                     /locus_tag="OPY25_002488"
     CDS             complement(13145..13948)
                     /gene="suhB"
                     /locus_tag="OPY25_002488"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HCS0928083.1"
                     /translation="MHPMLTIAVRAARKAGNVIAKNYETPDAAEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGEHVGTDQDVQWVIDPLDGTTNFIKRLPHFSVS
                     IAVHIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIIGKLFTECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMMTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            14067..14798
                     /gene="trmJ"
                     /locus_tag="OPY25_002489"
     CDS             14067..14798
                     /gene="trmJ"
                     /locus_tag="OPY25_002489"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HCS0928084.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAQIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGDAADHEETPYPLVDDLERFYGHLEQTLLSTGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGK"
     gene            15040..15534
                     /gene="iscR"
                     /locus_tag="OPY25_002490"
     CDS             15040..15534
                     /gene="iscR"
                     /locus_tag="OPY25_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HCS0928085.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDAGSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRASGRAQDAIDV
                     KLRA"
     gene            15715..16929
                     /gene="iscS"
                     /locus_tag="OPY25_002491"
     CDS             15715..16929
                     /gene="iscS"
                     /locus_tag="OPY25_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCS0928086.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFLTLDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIAELVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLNELEAAMRDDTILVSIMHVNNEIGVV
                     QDIATIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRIRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMETEMARLRGLRNR
                     LWNGIKDIEEVYLNGDLEQGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSATLE
                     PSYVLRALGMNDELAHSSIRFSLGRFTTEEEIDYTIDLVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            16957..17343
                     /gene="iscU"
                     /locus_tag="OPY25_002492"
     CDS             16957..17343
                     /gene="iscU"
                     /locus_tag="OPY25_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HCS0928087.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDDNVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIADELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            17372..17695
                     /gene="iscA"
                     /locus_tag="OPY25_002493"
     CDS             17372..17695
                     /gene="iscA"
                     /locus_tag="OPY25_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HCS0928088.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTAEDTVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFSNPNVKDECGCG
                     ESFHV"
     gene            17892..18407
                     /gene="hscB"
                     /locus_tag="OPY25_002494"
     CDS             17892..18407
                     /gene="hscB"
                     /locus_tag="OPY25_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HCS0928089.1"
                     /translation="MDYFTLFGLPARYQIDTQALSFRFQDLQRQYHPDKFANGTQAQQ
                     LAAVQQSATINQAWQTLRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLTLREEL
                     DDIEQSKDDARLESFIKRVQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            18420..20270
                     /gene="hscA"
                     /locus_tag="OPY25_002495"
     CDS             18420..20270
                     /gene="hscA"
                     /locus_tag="OPY25_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HCS0928090.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     PDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQARYPH
                     LPYRFKASVNGLPMIDTAAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAITAKI
                     ALSDADTVRVNVAGWQGEITREQFNDLISALVKRTLLACRRALKDAGVEPQDVLEVVM
                     VGGSTRVPLVRERVGEFFGRTPLTAIDPDKVIAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDSQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDGE
                     IASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAA
                     AHLSAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV"
     gene            20272..20607
                     /gene="fdx"
                     /locus_tag="OPY25_002496"
     CDS             20272..20607
                     /gene="fdx"
                     /locus_tag="OPY25_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HCS0928091.1"
                     /translation="MPKIVILPHQDLCPDGAVLEAETGETILDVALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEEEDDMLDKAWGLEPESRLSCQARVTDDDLVIEIPR
                     YTINHAREH"
     gene            20619..20819
                     /gene="iscX"
                     /locus_tag="OPY25_002497"
     CDS             20619..20819
                     /gene="iscX"
                     /locus_tag="OPY25_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HCS0928092.1"
                     /translation="MGLKWTDSREIGEALYDAYPDVDPKTVRFTDLHQWICELDDFDD
                     DPNASNEKILEAILLVWLDEAE"
     gene            20873..22156
                     /gene="pepB"
                     /locus_tag="OPY25_002498"
     CDS             20873..22156
                     /gene="pepB"
                     /locus_tag="OPY25_002498"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HCS0928093.1"
                     /translation="MTEAMKITLSTQPADARWGDKATYSINNDGITLHLNGKDDLGLI
                     QRAARKIDGLGIKQVALTGEGWDTERCWAFWAGYKGPKGVRTVMWPDLDDAQRQELDN
                     RLTIIDWVRDTINAPAEELGPEQLAQRAVDLLCSVACDSVTYRITKGEDLREQNYMGL
                     HTVGRGSERPPVLLALDYNPTGDKDAPVYACLVGKGITFDSGGYSIKQSAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIIRYRNGKNVEVMNT
                     DAEGRLVLADGLIDASAQHPRLIIDMATLTGAAKTALGNDYHALFSFDDTLAGRLLTS
                     AAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSATYPAGASTAAGFLSHFVENYREGW
                     LHIDCSATYRKAPVEQWAAGATGLGVRTIANLLTA"
     gene            22266..23042
                     /gene="sseB"
                     /locus_tag="OPY25_002499"
     CDS             22266..23042
                     /gene="sseB"
                     /locus_tag="OPY25_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HCS0928094.1"
                     /translation="MSETKNELEILLEKAATEPAHRSAFFRTLLESTVWVPGSAAEGE
                     AIVEDSALDLQHWEKEDGTTVIPFFTSLEALQQAVEDEQAFVVMPARTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLLAEEGSPLSTQEVLEGGESLILSEVAEPPSQMIDSLTT
                     LFKTIKPVKRAFLCAIKEHADAQPNLLIGIEADGEIEEIIHAAGNVATDTLPGDEPID
                     ICQVRKGAQGISHFITEHIAPFYERRWGGFLRDFKQNRII"
     gene            complement(23611..>24130)
                     /locus_tag="OPY25_002500"
     CDS             complement(23611..>24130)
                     /locus_tag="OPY25_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF5066 family protein"
                     /protein_id="HCS0928095.1"
                     /translation="SLKALLAYDRDLLSNYNMPVIETLQRFIDNEGVIHSYSPDEEAY
                     YGAGMDSSGIDIEDLMPVWSNDPRLPALIRIDHVGDQAIFIYITERDANGEYPIARME
                     RNEFWLAESSLVEYLYNIISGAKDIGFTEEDLHLPQWKAQQKMNEQRDAALLDLEDYH
                     EAFWAKLDALVD"
BASE COUNT         5567 a         6195 c         6766 g         5602 t
ORIGIN      
        1 caaacatgaa aaaactgata gattgatttt tttgaattaa catataaata tcatgaaagg
       61 ataaatattg tttaattaca aagggttata tttacatttc tttgcgatga atatgttgcc
      121 aaaattaaca taagctattt tttgcaacat atttttcaca aaataaaagc gaaaaattta
      181 atatcttttc gcttttattt gtcatggttc agcgttaaat ttaatcttct gccagaaaac
      241 tattcagata agggacaatt ttctgaacgg atgtctgaaa tacgccgttc tcgatccagt
      301 acagcgtatt ttcacctgga cgtaaattaa aggcggtcag ataggcatca gcggccagac
      361 gattctcacc tttcatttcg taaactttcc ccaacaggac atagttaaac cacgacattt
      421 caagctcgat gcttttattg atttcctcat acgctgcatc gatatcacct ttgcccaaaa
      481 gatcaacggt cttgatttta taataaacag acgttttctc aacgcccgga atttgatcta
      541 tttttttaaa ctcttcgttc agcgcagcca cttgttcttt atcaaacggc tgttgtgatt
      601 gccgtaatac atctaccagc actttatatt cataggcata gttgaaatca ggcgtttcct
      661 taataatgcc attcagaata tcgccggctt tacttagcgc ctgcgcatcg ccgctcagaa
      721 taagctggcg cgcctcataa aaacgcatca gcgcggtatt ttgcggcgtt ctgaacaggg
      781 ccagttgttc tcgcatacga ttaggccagg gctgtgttaa aacgaaagac aggctattaa
      841 acagatcatc ctggatggac aactggttag tattggtgac gaaataacgc ttatccagca
      901 tggttgaacc atcggcgtta tcaatgagca ccacagacat aaagcactgc tgcgcccgat
      961 agtggcgctg attgacaaac tgaatggtta acgtcttacc ggagttgctt ggctcattga
     1021 cccggtaatt ggttttatcg tgcaccataa aggtcgagta ggtgttcagc aggtcggtga
     1081 ttaagccgcc cagaccgatg gcgtaggact cctgcgagac ccagttatta caggaattgc
     1141 cgccttcaaa acgaacatct atatctcgtg ggttaagtaa taaccgcgtt tttgttaccg
     1201 cggcattatg atctaccacc gacatcacga taaacaccac cagcgtcgcc agcgagagca
     1261 ggaacatcac ccacgtccag aaagcggcga tacgcggctt tttcgccttt ttagtcggcg
     1321 tttgcaaaga ggcgggcggc acaggcgcag cggcaggaac cccctctgtc ggttctgcat
     1381 tcgtcgctgc gatcggcggc ggcggcgacg ttgataaatt atcgatctca tcgctatttt
     1441 cttcgcacca gataaccggc gccgtcagct tatagccgcg tttaggtacg gtaacgatgt
     1501 attcagcatt gctgtctccg ccatctctta atgatttgcg tagttcagaa atgctttggg
     1561 tgacaacatg gttggtcacg atggtgcgca tccagacatg atcaataatg ttatcccggc
     1621 ttaacacttc atccggatga tgcgcaaaat acatcagaag atcgatcagc cgtggttcaa
     1681 gagtaatctg gcgtccctga cgactgatct gattaacaga aggtgtaacc agccactctc
     1741 caatgcgtac aacaggttgc tgcataaaaa gatgccctaa cgagctaagt caaacgttaa
     1801 taataacacg atttgcacag acttttttat tccccttttt tgtaaaagaa aggcataaaa
     1861 agcagcgcaa taagcaggag aacggggagg aaaacgggcg ttcgccttaa cgataacgcc
     1921 cgttttttca gcggatttct tgcaattaca gcactttatg cgggccgaag cattcgtaat
     1981 gaatgttttc gttattcacg ccaagtgaaa ccagttgttt tgcggcaaac tgcataaagc
     2041 ctaccgggcc gcaaagatag aactgcattg ccggatcgct gatcgcggct tccagtttgc
     2101 ttaaatccat cagcccttcg ctgtcaaaga cgcgttgggc gcgatcggcc tcggttggct
     2161 cgcggtacca ggtatgggca gtgaaacgcg gcagtgtacg gcccagctcg ctcacttcgt
     2221 cggcaaacgc atggacgtcg ccgttctccg ccgcgtggaa ccagttcacc tgcgcggtat
     2281 gctgttcttt cgccagcgta tcgagcatcg ccaacatcgg cgtctggccg acgccagcgg
     2341 aaatcagcga aacgggggta tcagcggcga cattcataaa gaagtcacct gccggcgcag
     2401 ccagatgcac cacatcgcct acgttggcgt gatggtgtaa ccagtttgat acctggccgc
     2461 cgtcttcacg cttcacggca atacggtacc ctttgccatc gggtttacgg gtcagtgaat
     2521 attggcggat ctcctgatgc gcaaaacctt ccggcttcag ccagacgccc agatactgcc
     2581 cgggacggta ttccgccacc gtaccgccgt cgaccggttc aaactcaaag ctggtgatca
     2641 gtgcgctacg cggggttttc gcaacgatgc ggaaggggcg cgtgccttcc cagccgccgt
     2701 ctttgctggc gttctcgtga taaatctcgg cttcccgatg aataaagacg ttagccagta
     2761 cgccataggc tttaccccat gcgtccagca cttcctggcc cgggttgaac atttcatcca
     2821 gcgtcgccag cagatgcgtc ccgacgatgt tgtactgctc cggcttaatc tggaagctgg
     2881 tgtgcttctg cgcgattttt tctaccgccg gcagcaacgc cggtaaattt tcgatattgc
     2941 tggcgtaggc cgcgatagca ttaaacaggg cttcgcgctg atcaccgtta cgctggttgc
     3001 tcatattgaa gatttctttg agctccgggt tatgcgtaaa catacggtcg tagaagtggg
     3061 cggtcagttt cggtcctgtt tcaaccagca ggggaatggt ggcctttact gtagcgatgg
     3121 tttgtgcgtc aagcatacgt gcttccttta tgtgaaaatc taataatgta tatcaaatgc
     3181 atcttataaa aatacccttg cattgtaaat ggatcttctc tgctttacgt tatggaggta
     3241 acaacgtgaa aaatctgcat cacaaagctg aaaagaaatc cgttgaaatt cgtcaggctc
     3301 tcgttcagga aacccttatc tgacgcatag gtaatcgttt gcgtaaaaac ctttgtcaag
     3361 acctgttatc gaagaatgat tcggttatac tgttggccga agtcccacgg actgcctttt
     3421 caggcacaaa ttttattgtt agctgagtca ggagatgcgg atgttaaagc gtgaaatgaa
     3481 cattgccgat tatgatgccg aattgtggca ggctatggag caggaaaaag tacgtcagga
     3541 agagcacatc gaactgatcg cctccgaaaa ctacaccagc ccgcgcgtga tgcaggcgca
     3601 ggggtctcag ctgaccaaca aatacgctga aggatatccg ggcaagcgct actacggcgg
     3661 ttgcgaatac gttgatgtcg tagagcagct ggctatcgac cgcgcgaaag aactgttcgg
     3721 cgccgactac gctaacgtgc agccgcactc cggttctcag gctaacttcg ctgtttacac
     3781 cgcgctgctg cagccgggcg ataccgttct gggtatgaac ctggcgcagg gcggccacct
     3841 gactcacggc tccccggtta acttctccgg taaactgtac aacatcgtac cttacggtat
     3901 cgatgagtcc ggtaaaattg actatgacga gatggcgaag ctggccaaag agcacaagcc
     3961 gaagatgatt atcggtggct tctctgccta ctccggtgtg gttgactggg caaaaatgcg
     4021 tgaaatcgct gacagcatcg gcgcatacct gtttgtcgac atggcgcacg tggcgggcct
     4081 gattgccgca ggcgtttacc cgaacccggt tccgcacgct cacgttgtca ccaccaccac
     4141 ccacaaaacc ctggcgggtc cgcgcggcgg cctgatcctg gcgaaaggcg gcgacgaaga
     4201 gctgtacaaa aaactgaact ccgccgtctt cccaagcgcg cagggcggcc cgctgatgca
     4261 cgtgatcgcg ggtaaagcgg tagcgctgaa agaagcgatg gagccggagt tcaaagttta
     4321 ccagcagcag gtggcgaaaa acgccaaagc gatggtggaa gtgttcctga accgcggcta
     4381 caaagtggtg tctggcggca ctgagaacca cctgttcctg ctggacctgg tggataaaaa
     4441 cctgaccggt aaagaagctg acgccgcgct gggccgtgct aacatcaccg tgaacaaaaa
     4501 cagcgtgccg aacgatccga agagcccgtt cgtgacctcc ggtatccgta ttggttctcc
     4561 ggcggttact cgtcgcggct tcaaagaagc ggaagtgaaa gagctggctg gctggatgtg
     4621 tgacgtgctg gacaacatca atgatgaagc caccattgaa cgcgtgaaag cgaaagtgct
     4681 ggatatctgc gcccgcttcc cggtttacgc gtaagcgttt gtgttgtgta aatggcccga
     4741 tggcgctgcg tctgtcgggc attacttatg cgccataacg tgacgccgcc ggaagtcatt
     4801 atccggcggc gttgccgttt gaacttctcc ctccgcctgt tacccttgcc agcgcaaccg
     4861 tttaccgcca gactatcgcc tccaaacggg agggaatcat ggcattgcat tccacgcgct
     4921 ggctggcgct cagttatttc acctacttct ttagttacgg tatttttctg cccttctgga
     4981 gcgtctggct caaaggtctt gggctaacgc cggaaaccat cggtcttctg ctgggcgtgg
     5041 gtctggtcgc gcgttttctc ggtagtctgc tcattgcgcc tcgcgtaagc gatccttcgc
     5101 ggttgatctc cgcgctgcgc gtcctggcat tgctgacgct ggtatttgcg ctggcatttt
     5161 gggcaggaac gcatgtcgcg tggctaatgg tggtgatggt tgggtttaac ctcttctttt
     5221 caccactggt gccgctgacc gatgcgctgg ccaatacctg gcaaaagcaa attaccctgg
     5281 actatggtcg ggtgcggctg tgggggtcca tcgccttcgt gatagggtcg gcgctgaccg
     5341 gtaagctggt gagtttatac gattaccagg cgattctggc gctactgacg ctcggcgtcg
     5401 cctcgatgtt gctgggtatg ttgttacgtc ccagcgtgcc gccgcaaggg gaaagccgtc
     5461 agcaggagag cgcaggctgg cccgcctggc gtacgctggt ggcacaaagt tggcgttttc
     5521 tcgcctgcgt ctgtttgctg caaggggcgc acgccgccta ctacggtttt agcgccatct
     5581 actgtcaggg ggctggctat tcagcatcgg cggtcggcta tttatggtcg ttgggcgtgg
     5641 tggcggaagt gatcattttt gccctgagta aaaagctatt ccgccggttt agcgcccgcg
     5701 acttgctgtt gctttctgct gtgtgcggcg tggtacgctg gggactgatg ggctggagta
     5761 cggcgttgcc gtggctgatt gtgatacaaa tcctgcactg tggcacgttt accgtttgcc
     5821 atctggccgc tatgcgctat atcgctgcgc gtcagggaag cgaggtgatt cgtttgcagg
     5881 ccgtctattc cgctgtggcg atgggcggca gtatcgcgat tatgacggta tttgccggtt
     5941 ttctgtatca acatctgggc ggcggcgtat tctggattat ggcgctggtg gcattgcccg
     6001 ctatcttcct tcggcccaaa gtggttgccg cgtcatgatt ccaggatctt gcggatctgc
     6061 tgctgttggt gctctgtgag ggcgcgatcc gcatgaatta atggcggtga gaagagcggt
     6121 agcggcgtgg cgtaaggggt aacaatcagc gctacgccgc gcgggcatcc ctctttttga
     6181 aacgcctgga gcgatatccg tctgatattc agcggcaata gggtcagttc acgcagttgc
     6241 tgctcaatat gcgtctccag cgcatcattt ttatccgcta acaatacgat ctgtctctca
     6301 tgcaaatcgt tatcctgcat cagccaggcg ccgaaaatca ctgccaccag ccccgtctct
     6361 tcctcggaaa agtggatacc atattcggct tcaaacccgg cgagcgcctc acgtgtggtg
     6421 cgaaccagac gcggataaag acggttgaac tcttccggaa gcgtattatc gatgccaatc
     6481 gtgaataaac ttcggttcag cgcctgggcg agatggacat acagctgatc gttaagccct
     6541 tgttcgtcgc tgaagcgtac gttccctttt tctcgaaagc gcagcaccag ccgcgccacc
     6601 tccagtcgca gttgctgcgc ccgttgatgc gtgtcgcgaa tcgggtcggg gaggcgaatc
     6661 attgaaaaca gtaacgccat aaacagcgct tcattgagcg gtgcggcctg catcacgtgg
     6721 cgctgccagt gacgaccaat ttcctgggcg agtggatatt ccgcacacga ctgcgcccaa
     6781 atctgctgta caggattgaa ttccggggtg atgccggcat ggtgttgtag cagacaatac
     6841 tgtaaaaaga gacgcaggaa ctgcacgtcg cgatgttcaa atggtttttg caaccggcgg
     6901 gcgcacagat tgatgagcgc gtgcagatta atatcgtcat acagcggacg cgcgataccg
     6961 cgctgcttta gcgcgttttt taaggccggg gtaaactgtt gcgtgacgaa ggtcgggcat
     7021 aaacgcaggc cgcgcctgag ccagtgtaaa aggcaaaggc gctgatcgag tgctgtacct
     7081 tcgatccgat agcaaccgtt ctggcatgtt gtgatggcaa ggcgatgata gcgctggatc
     7141 tccaggcttg tgtcagtgat atcctcacgg gcagtatcat catcaacgcc attaagcgcg
     7201 ctgaagattt ccaccgtggc aattggctcc ggctggaaaa gcgtcagcaa tacctgacag
     7261 cggcgctggg gagcggaaag tacagatggt ggggcaattg tcggcatcat ctgtcaggtc
     7321 tcccgttagt ttatctggta aggatagcta aagtttgcat gtgaaaaatg tgataagtgt
     7381 gcttttaggc caggaatgct gaggagtgtc acagaatttt tatcgcgagg aacagatgaa
     7441 gccagtgaaa cgcagcgcct taatactatt tctcgccgtt ttatctttcg tggcggcggc
     7501 gcatccgcac agcttcatcc gtctgcaaac gcaggtggtc agtgaaaatg agcaatttgt
     7561 ggcgttaaaa atgcgctgga caatggacgc gctgacgtcc gccgatctgc tgtatgacgc
     7621 cggaaacgcg gcgccgggtt cagaaatatg gaaaaagttg gcggcggaag tgatggctaa
     7681 cgtacttggg cagcactact ttacagaagt gtggcgcaat ggcgcgaaag tgaagtttaa
     7741 aaacaggccg acagaatacg gtatgacgcg tgacgcgcat caggcggtat tgacctttac
     7801 gctgccgctg gctgaaccgc agccgttaag cggccagact tatacctttt caacgtttga
     7861 tccctcttat tatgtcgata tgcattatga ccaggacagc gatatcacga tgccggaacc
     7921 gctgcgcgaa aagtgtcgga ttcaggttta tactcctgcg cccggcgaag agacgctacg
     7981 tttcgcccag tcgctggata aagaggacgc gccgccggag gatatggatt taggtaaaca
     8041 gtttgcccaa acggtgacct tgcaatgtca gtaatttttt ctcaacgcac tccggggcga
     8101 cgctggctct cgctgtggcc attggcgtta ttcctgctgc tgatgctggt tggcggtctg
     8161 tggatatggc aggcctggcc gcaggtgatg ctgaaaagcg ctctttggca gcgggacgtg
     8221 aatcagcagt tgagcgcgct gcttaatgcg gtggcgacgc atcctgagcg ggcgggcgga
     8281 tcgttgcttc tgctgagttt tatgtatggc gtgcttcatg cgtggggccg ggacacggca
     8341 aagtggtgat cgcgacatgg ctggcgacgc atccttcgaa gctgaaatca agtatcgtgt
     8401 taaccctcgc cgccgcgtta ttgcaggggg tcgtggctat cgggttggtg gtgggcgtgc
     8461 tgaccgtatt gcaacttccg gccaggcagc tccatctgag cggtttctgg ctggaaaagg
     8521 ggagctatgc gttagttggc gggctgggca tcttgctgtg ctggcgggcc ataaaaaggt
     8581 tacgcgcgct gctacgtaaa cctgtcttta tcgcttttac gccgcgccat gttcaccatg
     8641 aaaaatgcgg ctgcggacat cagcatctac cgacgcagga acaattgcat agcggcgatg
     8701 actggcgcgc gcgactcatg atcgtactgt ctatggggat gcggccctgt tccggagcga
     8761 taatggtgct gttattcagt aaagtgattg gcgtttttag ctggggaatg gcgtcggtac
     8821 tggcaatggc ggcgggaacc tcgctaacga ttacttcgct ggcgctgctg gtacacactt
     8881 ttcgtgctct ggcggtgaag ctcagtggaa acaaagcgcc ggcgttatgg cggcaggtag
     8941 gctggtcaac gctggcgctg gccggagggg tcatactgct tgtcgcggcg ctggtcatgt
     9001 ggtttagcgt gccgcagcct gtgggcgggc tgcggccatg gcgtggttga ctagtgcccg
     9061 gcgggtttga gatgcatccg cgcgacggat tcgtcttcgg cccagtaaat gcgttcggcg
     9121 accatcgctt ccggattgag ctgaacgccg cgcagtaccc gttctttaaa acgcagatag
     9181 ccgcctttgt cgatcagatg gcccatatgt agatagatcg gttttccgcc gagcatctct
     9241 ttttcaaatt catacaggtt aacgatcacc tgctttatca catcttcagt cacccagttg
     9301 aggaagagct tgccgacgcg cggcgtcttt ttactggtgc gtccgcccag acggacttgc
     9361 cagagctgat ccggcttacg ttgccaggcc agcgtcggac aggccagcac gcactcgccg
     9421 cagccgatac aggcggactc ttctttgacc gctttgccgt tcttcagcgc caggcagcct
     9481 accgcgtggt gactacaggc cttcacgcag gcgccgcaac cgatacagcg atcggcagtg
     9541 aagcgcattt tcgccacgcc aataattccc agatcggcca ttgacgcctt cgcgcaatca
     9601 ttcgggcagc caacaatgac cgttttgaga tgataagggc tgggatagac cagtttttca
     9661 agacgacggg acagaccggt cgtgtcagtg ttggctttct ggcaaatgcg gttcccctga
     9721 caggcgacaa tatttcgccc gccaatagcg agatagcccg ctttggtatc ctcaacctgg
     9781 acgtcgcaca gttctatttc aatctcgcga agaaatggct ccagcgcagc gttcacgttg
     9841 tcgatatctt cgtaacggat acccggcatc gccagcttct ggcgggtagt gaggtgaatt
     9901 tgtccgttgc cccaggtttc ggcgatgtca cgcgccaccg ttagcaaatg cgcgggcaaa
     9961 ataccgccgg gaatgcggac gctgatcatg gcttcgccgc gcacttttga taggcgatat
    10021 tcgtttttcg cacgggcttt aatgatatca atatcaatgc tcatgatgtt ctccttaatc
    10081 ggcaaaacgt tgcgcgacgg cgtagttaaa tatcgggccg tcggtgcaga catacacttc
    10141 gcccatacgg cagtggccgc acttcccgac ggagcaggcc atccggcgtt cgtagtccac
    10201 ccaaatttgc tccggcttga gccctttttg cagcagcatt tttacggtaa aggtaatcat
    10261 tattggcggc ccaacgacga tggcctgcat ggtgtcgata tcgctaagcg tcatgtcggc
    10321 aagccgatcg gtcacccgac caatctggta acggtcatca gcctcgcctt catccagcgt
    10381 gagcaccaga ttatgtttgc cgtgccacgt cgccatttct tctttgtaca gcacgcaatc
    10441 gcgattttta tagccgagaa tcatatccag ttgaccaatt tcctggggat tctcaacgaa
    10501 atagcgcatt aagcctttca ccggcgcgac gcccgtgccg cctgcgacaa ccagtaaggg
    10561 tttatggcgc agagtatcga ccggatagcc attgccatag cagccgcgta gccacacgtt
    10621 gtcgccttct ttcagcgtaa agagggcgct ggtcactttt ccgacattac gaatcagcag
    10681 atctatccag ccatcgccgt agtcggaaac ggagatgggc gcttcgccga cgcgcggcag
    10741 cgacacctca acaaattgcc cccagtgcgc gggaaaatcg acggccacgc ggaaattcca
    10801 ctccagcggc gtgtggcgag taatactgag gatgcggtac gccgcaggca gcaaactgtg
    10861 ctgcggttta tcatgacagg aacaatgtga catgcgttat gcctcctctg ccagcgcctg
    10921 ccgaacggca gcggtcattt tgttaataat caaagaaaat ttgatgtatt gcgggcagcg
    10981 atcgtcgcag cggccgcagc cgacgcacat atgttcaatg ccgttgcgcg ctttgtagtc
    11041 attgacctta tgcagggcgc ggtagcgcag acgctcgccg ggtttttcgc gaaaaccatg
    11101 accgccggcc atgtcgctaa agcccggcac catgcagctt gcccactggc gacggcgttc
    11161 gccgcgctgc ggattttcat cataggcgac gtcaaagacg ctatagcagg tacaggttgg
    11221 gcacccggta gtacagcggc cacaactgat gcagcggctg tcgtaggcgt cccatagcgg
    11281 atggcgagtg agaatgtcgc gaattttttg cggatcgcgg caaacgctgt ccggcgtgac
    11341 gacggtttcc cggttttcgc tgacgaaaga gggggtatag tcagcctcct gccccagtcc
    11401 ttgtatcgcc gcctcgataa agggatcgcg gatgctcaca agcgcgccct catcgctaaa
    11461 acgcatggcg gcgctataac agtcagtttt attagtaccc attgagacgc agaaacaatt
    11521 ttcgaagctt tcttcacact caataaggac gaaacgaata tgctcccgta gcagttgata
    11581 actgtaatcg gaattattcc catttgataa atacatataa tccagccgcg acatggcgtt
    11641 aatgtcgcag gcgcgggcaa agatgattat cggggaggtg tctgtctcgg caatttgaat
    11701 ggtgttttta tcgaaataaa agagcgtttc ggtgataggg gcgataatgg tattcggcga
    11761 catgtgcgat ttctcgtgcc agatgagatc gcgccagccg ctaatccgtt gataaataat
    11821 gttgtcagtg tcggaaaaac gcccgccgcg aaactctgcg gacggggcaa acacgcgcca
    11881 ttttttgttt aatcgctgga taagcagact aaactcgtca ggcgtaattt tgatagccat
    11941 cacatactcc acagtaatat tcaggaaaaa caaatgaaaa taaattgtta taaaaatcag
    12001 atgaatatta ctgttacgct agcgctaatc cgccgccttc gctaacggga aaaaatggtt
    12061 tttactatcg gtataataaa tatattctta atcataaaat atgcatatat acagcgtcgc
    12121 gctatttagc ggatagcgct gtctgaataa aattaatcat cgcatcgcgg taaaggtttg
    12181 cataacgtcc ggaaaaagca tcaatgtgat cgccgtcagg aatgaagatt ttttgtttgg
    12241 gctcccgggc gagggcatac aatttctcac tgtcctgcca gggaataaca tggtctgccg
    12301 tgccatgaag aatcaatacc ggaatggggc tgacgctggc gatattgcga tccgcgctat
    12361 agcggtcatc aagcaaatag ccgctgcccg ggatcatctg gttggcgatg gaggaatagg
    12421 atgaaaacgt tgagtcgagg acaatcgcac gtatgcccgc ctggtcggcg tagcgcatat
    12481 ttgcgcagcc tacgcagtgg cctacggcgg ccagtacatt attgccgccc aggctctgcc
    12541 ccagcagtac caggcgctcg gggttaacgt cggcacgatg ccgcacataa tctatcgcgc
    12601 ttttcgtatc gttcagtagc ccctcttgtg atggggtgcc ctcagattcg ccaaacccac
    12661 ggtaatcaaa cataaacagg tttacgttgc gttctggcag ccaactgact aacggccagt
    12721 gcgccgacat atttccggcg ttgccatgga catgaatcac cgtcgcgacg gcgttttccg
    12781 gcctgccgaa agcagtagga ataaaccagc cgtgcagatg cgtgccatct ttggcggtaa
    12841 aggtaatgga ttcagcttcg gcaggggttg gtccatagac tttattgtcc gggtaataaa
    12901 aggcattgat cgctacgcgg ggtagcaggt aaatacagac tacaatgata aacagaataa
    12961 aaagggattt gacgatgcgt cgggtatgtt gaagggtcat gttcgcttcc ttgccgcttt
    13021 atgtccatag cggagcaggg agcgatcgta caaaaacatg caggcaagta aagcgatgag
    13081 gtggtgttta ggaaaaacgc ctgaaaaggc acggcggatg agtggcccca tccgccgaag
    13141 agacttagcg cttcagcgca tcgctcagtt cgtcgcgcat attcgccagc atggctttaa
    13201 cgacgcgcgg attccccgcc acgatattac cggtcatcat gtagttatga ccgccggtga
    13261 aatcgctgac gataccgccc gcttcacgaa ccagcagttc gcccgcggcg aaatcccacg
    13321 gacgaaggcc aatttcaaag aaaccatcga cacgacctgc agccacatag gccagatcca
    13381 gcgcggcgga accggtgcgg cggaaatcgg cgcattcggt gaacagcttg ccgataatat
    13441 taatgtaggt ggtcgcgtat tgtttggctt tgaacgggaa gccggtagcg aggatagtgc
    13501 cgtccagatc gcgcgcggta ctgccgcgca gacggtagcc gttcagctgc gcgccctgac
    13561 cgcgggtggc ggtgaacagt tcgttacgca tcggatcgta aacgacagcc acttcagtac
    13621 ggcctttaat gtgtacagca atggaaacag agaagtgtgg cagacgtttg atgaagttgg
    13681 tggtgccatc cagcggatcg ataacccatt gaacatcctg atctgtgcca acgtgctcac
    13741 cgctttcttc ggtgataata gtgtgttgcg ggtaagattt gcgaatggtg tcgataatta
    13801 ccgcttcagc ggccttatct acgttggtca caaaatcgtt actgcctttt tggctcgctt
    13861 ctgcagcgtc cggagtttca tagtttttgg caattacatt acccgccttg cgcgctgcgc
    13921 gcacggcgat ggtcagcatc ggatgcatcg gtctctctca ctggatgtta aagaacggga
    13981 aaacggcgca gagtatagca gcgagatcgg aatctgtctt ggttttatgg taagatgtcc
    14041 gaataatctt tagctgaaga aagacaatgc tgcaaaacat tcgaattgtg ctggtggaaa
    14101 cctcccacac cggcaatatg ggctctgtgg ctcgcgctat gaaaaccatg ggcttaacta
    14161 acctgtggct ggtaaacccg ctggtgaaac cggactccca ggccatcgcc ctggcggcag
    14221 gcgccagcga tgtgatcggt aatgcgcaga tcgtcgatac gctggacgaa gcgttggctg
    14281 gctgtagcct ggtggtcggc accagcgccc gctcccgcac tctgccgtgg ccgatgcttg
    14341 atccgcgcga gtgcggctta aaaagcgtag cggaagcggc aaatacgccg gttgcgctgg
    14401 tttttggtcg tgagcgtgtc gggctgacta acgatgagtt gcaaaaatgc cattatcacg
    14461 tcgcgattgc cgctaacccg gagtacagct cgttgaatct ggcgatggcg gtacaggtca
    14521 tcgcgtatga agtccgcatg gcctggctgg cgacgcagga aaacggcgac gcggcagatc
    14581 atgaagagac accgtatccg ctggtggacg atcttgaacg tttttacggc catctggagc
    14641 agacgttgct ctccactggc tttattcgcg aaaaccatcc ggggcaggtg atgaataaat
    14701 tgcgccgtct gtttacccgc gcccgcccgg aaagccagga gttgaatatt ctgcgtggga
    14761 ttctggcgtc tattgagcag cagaataaag gcaagtaacc gcgttaatgc cggatggcgc
    14821 ttcgcttatc cgacctacaa atcgtgcggc ctgtaggccg gataagcgaa gcgccatccg
    14881 gcacatcaat accgcacgga acgctaaata cctgactaat ttactcaagt aaatagttga
    14941 ccaatttact cgggaatgtc agacttgtcc ctgctatgca atacccccat tttacaataa
    15001 aaaaccccgg gcaggggcga gtttgaggtt aagtaagaca tgagactgac atctaaaggg
    15061 cgttatgccg tgaccgcaat gttagacgtt gcgctcaact ccgaagcggg cccggtaccg
    15121 ttggctgata tttctgaacg tcaggggatt tccctttctt atctggaaca gctattttcc
    15181 cgtttacgta aaaacggtct ggtttccagc gtacgcgggc cgggcggcgg ttatctgctg
    15241 ggtaaagatg ctggcagtat cgcggtcggc gaagtgatca gcgcggttga tgaatccgtt
    15301 gacgcgaccc gttgccaggg caaaggcggc tgccagggcg gcgataaatg cctgacccat
    15361 gcgctgtggc gtgatttaag cgatcgtctg accggttttc tcaacaatat tactttaggc
    15421 gagctagtga ataaccagga agttctggat gtgtctggtc gccagcacac gcatgacgcg
    15481 ccgcgcgcca gcggtcgtgc gcaggacgct atcgacgtta aattacgcgc ttaattaaaa
    15541 tattacgcca tctcttctgg cggcctcatg cggtgaatgc cgcggtcgtc tgaaggatga
    15601 agcgtaaaaa agaattcaga atcaggccgg gacgcggacg tcccgtcaac acggtcgtac
    15661 atccagccgg ttgcctgatt ccttgcattg agtgatgtac ggagtttaag agcaatgaaa
    15721 ttaccgattt atctcgacta ctccgcaacc acgccggtgg acccgcgtgt tgccgagaaa
    15781 atgatgcagt ttctgaccct ggacggaacc tttgggaacc cggcgtctcg ttcacaccgt
    15841 ttcggctggc aggctgaaga agccgtcgat atcgcccgca accagattgc tgaactggtc
    15901 ggcgccgacc cgcgtgaaat cgtctttacc tcaggggcga cggagtccga taacctggcg
    15961 atcaaaggcg ctgccaactt ttatcagaaa aaaggcaagc acatcatcac cagcaagacc
    16021 gagcacaaag cggtgctgga cacctgccgt cagcttgagc gcgaagggtt tgaagtgacc
    16081 tacctggcgc cgcagcgcaa cggcatcatc gatctcaacg agctcgaagc agcgatgcgt
    16141 gacgacacca ttctggtttc catcatgcac gtgaacaacg aaatcggcgt ggtgcaggat
    16201 atcgcgacca tcggcgaaat gtgccgcgcg cgcggtatca tctaccacgt tgacgccacc
    16261 cagagcgtgg gcaaactgcc tatcgacctg agccaactga aagtggatct gatgtccttc
    16321 tccggtcata aaatttatgg tccgaaaggc attggcgcgc tgtatgtgcg tcgtaagccg
    16381 cgtattcgca ttgaagcgca gatgcatggc ggcgggcacg agcgcggtat gcgctctggt
    16441 actctgcctg ttcaccagat cgtcggcatg ggcgaagctt accgtatcgc gaaagaagag
    16501 atggagaccg aaatggcccg tctgcgcggt ctgcgtaacc gtctgtggaa cggcatcaaa
    16561 gatattgaag aagtttacct gaacggcgac cttgagcagg gcgcgccaaa cattctcaac
    16621 gtgagcttta actacgttga aggcgagtcg ctgatcatgg cgctgaaaga cctggcggtc
    16681 tcttccggtt ccgcctgcac ctccgccact ctggaaccgt cctacgtgct gcgcgcgttg
    16741 ggcatgaatg acgagctggc gcatagctct atccgtttct ctttaggtcg ttttaccact
    16801 gaagaagaga tcgactacac cattgatctg gttcgtaaat ccattggccg tctgcgtgac
    16861 ctttctccac tgtgggaaat gtacaagcag ggtgtggatc tgaacagcat cgaatgggca
    16921 catcattaat cggtatcgga atcaggagaa tttataatgg cttacagcga aaaagtaatc
    16981 gatcactatg agaacccgcg taacgtaggg tcgtttgaca acaacgacga taacgtggga
    17041 agcggtatgg ttggcgcgcc ggcctgcggc gacgtcatga agttgcagat taaagttaac
    17101 gatgaaggta tcattgaaga cgcgcgcttc aagacttacg gctgcggttc cgctatcgcc
    17161 tccagttctc tggtaacgga gtgggtgaaa gggaaatccc tggacgaagc gcaggcgatt
    17221 aaaaacaccg acattgcaga cgaactggag ctgccgccgg tgaaaattca ctgctctatt
    17281 ctggcggaag acgcgattaa agccgctatt gcggattaca aaagcaaacg cgaagcgaaa
    17341 taaaatagaa cgttaacatt gaggttttgt tatgtcgatt acacttagcg acagtgcagc
    17401 agcgcgagtt aataccttcc tggccaaccg tggtaaaggg tttggtctgc gtctgggcgt
    17461 gagaacctcc ggctgctcag gtatggctta tgtactggaa tttgttgacg agccgacggc
    17521 ggaagacacc gtgtttgaag acaaaggcgt taaggtagtg gttgacggca agagcctgca
    17581 atttctggac ggtacacagc tggacttcgt aaaagaaggc ctgaacgaag ggtttaaatt
    17641 ctccaacccg aatgtgaaag atgagtgtgg ttgcggcgaa agcttccacg tgtaactgtg
    17701 ttccgctgtt ataccgagtc attcgtgctg cagaaaagcg gcaagcgagt gaatccccag
    17761 gcgcttactt aagtaagtga ctgggggaac ccgcgcagac aacgcatctg cggcgcgaag
    17821 taagaaggta taaccccacc gtggtcgcct gcgtgtgggg tttgttctga caggctatcc
    17881 ctgagaatgt tatggattac ttcaccctct ttggcttacc agcccgttat cagattgaca
    17941 cccaggcgct gagctttcgt tttcaggatc tgcaacgcca gtatcaccct gacaaatttg
    18001 ccaacggcac tcaggcgcag cagcttgccg ccgtccagca atccgccacg atcaaccagg
    18061 cctggcaaac gctgcgtcac cctttgacgc gcgcggagta tctgctttcc ttacacgggt
    18121 tcgatctggc cagcgagcag catacggtac gcgacaccgc gtttctgatg gaacaactca
    18181 cgcttcgcga agagctggac gatatcgaac aatcaaaaga cgacgcgcgg ctggaaagct
    18241 tcatcaaacg cgtacaaaag atgtttgatg ctcgtcttca gcaaatggtg gaacagttgg
    18301 acaacgccgc gtgggacgcg gcggcggata cggtgcgcaa actgcggttt ctcgataaac
    18361 tgcgaagcag cgcagaacaa ctcgaagaaa agctgctcga tttttaactg gaatctaaca
    18421 tggccttatt acaaattagt gagcctggtc tgagcgccgc gccgcatcag cgtcgtctgg
    18481 cggcgggcat cgacttaggc actaccaact ctctggttgc gacggttcgc agcggccagg
    18541 cggaaacact gcctgaccac gaagggcgcc acctgttgcc ttcagtggtt cactatcagc
    18601 agcagggcca tacggtcggt tacgctgcgc gtgacaatgc cgcgcaggat acggccaaca
    18661 ctatcagctc tgtgaaacgc atgatgggac gctcgctggc ggatatccag gcgcgctatc
    18721 cgcatctgcc ttaccggttt aaggcaagcg ttaatgggct gccgatgatt gacacggcgg
    18781 ctggattgct caatccggta cgcgtatctg ctgatattct caaagcgctg gccgcgcggg
    18841 ctagcgaatc gctctccggc gagctggatg gcgtggtgat taccgttccc gcctatttcg
    18901 atgatgccca acgtcaggga acgaaagacg ccgcgcggct ggcaggcctg catgtactgc
    18961 gcctgctcaa cgaaccgacg gcggcggcga ttgcctacgg tctggactca ggcaaagaag
    19021 gcgttatcgc tgtttacgat ctcggcggcg gtaccttcga tatctctatc ttacgcctga
    19081 gccgcggggt gtttgaagtg ctggcgacgg gcggtgattc tgcgctcggc ggcgacgact
    19141 ttgaccatct gctggcggac tatattcgcg agcaggcggg aattgccgat cgtagcgaca
    19201 atcgcgttca gcgcgaactg ctggatgccg cgattaccgc gaaaatcgcc ttaagcgatg
    19261 ccgatactgt tcgcgttaac gttgcgggct ggcaggggga gatcactcgc gagcagttta
    19321 acgatctcat ttccgcgctg gttaagcgca cgctattggc ctgccgtcgc gcattgaaag
    19381 atgccggcgt tgagccccag gacgttctgg aagtggtcat ggtcggcggt tcgacccgtg
    19441 taccgctggt gcgtgagcgg gtgggcgaat tttttggccg cacgccgtta accgctatcg
    19501 acccggataa agtgatcgct atcggcgcag cgattcaggc cgatattctg gtcggcaaca
    19561 agccggacag cgaaatgctg ctgctggacg tgattccact ctctcttggg ctggaaacga
    19621 tgggtggcct ggtggaaaaa gtcattccgc gcaacaccac tatcccggtg gcgcgcgcgc
    19681 aggatttcac caccttcaaa gacagtcaga ccgcgatgtc tatccatgtg atgcagggcg
    19741 aacgcgaact ggtgcaggac tgccgctcgc tggcgcgctt tgcgctgcgc gggattccgc
    19801 cgctgccggc gggcggggcg catattcgcg tgaccttcca ggtagacgcc gatggcctgt
    19861 tgagcgtcac cgcaatggaa aaatccaccg gcgtcgaggc ctccattcag gtcaaacctt
    19921 cctatggcct gaccgatggc gaaatcgcct cgatgatcaa ggattccatg agttttgccg
    19981 agcaggacgt gaaagcgcgt atgctggcgg agcaaaaagt cgaagccgcg cgcgtgctgg
    20041 aaagtttgac cggcgcgcta actgccgacg ccgcgctgtt aagcgccgca gaacgtcaat
    20101 gcattgatga tgccgccgca catttaagcg cggtcgcaca aggcgatgat gttgacgcaa
    20161 tagaacaagc cattaaaaac gtagataaac aaacccagga atttgccgct cgccgcatgg
    20221 accagtcggt tcgtcgcgcg ttgaaaggcc attccgtaga cgaggtttaa catgccgaag
    20281 attgttattc tgcctcatca ggatctttgt ccggatggcg cagttctgga agctgagacc
    20341 ggtgaaacca ttcttgacgt tgcgctgcgc aacggcatcg agattgaaca cgcctgtgag
    20401 aaatcgtgcg cctgcaccac ctgtcactgt attgtacgtg aaggcttcga ctccttgccg
    20461 gaaagttcgg aagaagaaga cgatatgctg gataaagcgt gggggctgga gccggaaagt
    20521 cgactgagct gccaggcccg cgttaccgac gacgatctgg ttatcgaaat tccacgttac
    20581 acaatcaacc atgcgcgtga gcattaacag agggtagtat gggactcaag tggaccgata
    20641 gccgcgagat cggcgaagcg ttatacgacg catatcctga tgtcgatcct aaaaccgttc
    20701 gtttcaccga tctgcatcag tggatctgcg aactggacga ttttgacgac gaccctaacg
    20761 catccaatga aaaaattctg gaggcgattc tgctagtctg gttggatgaa gcagagtaag
    20821 tcaaataacg ggctgcccta cgacggcccg tttgctaata aggaaaataa caatgacaga
    20881 agccatgaaa attacgcttt ccacgcagcc tgccgatgcg cgctggggcg ataaagccac
    20941 ttacagtatt aataacgacg gtattacctt gcatcttaac ggtaaagacg atctggggtt
    21001 gatccagcgt gcggcgcgta aaatcgacgg cctgggaata aaacaggtcg cgctgacagg
    21061 cgaaggatgg gataccgagc gttgttgggc attctgggcg ggttacaaag gaccaaaagg
    21121 cgtccgtacc gtaatgtggc cggatttaga cgatgcccaa cgtcaggagc tggataaccg
    21181 cctgaccatt attgactggg tgcgcgacac cattaatgct ccggcggaag agcttgggcc
    21241 ggagcaactg gcgcagcgcg cggtggatct gctgtgcagc gtcgcgtgcg atagcgtcac
    21301 ttaccgtatc accaaaggcg aagatctgcg cgagcagaac tatatggggt tgcataccgt
    21361 aggccgtggt tctgagcgtc cgccggtact gctggcgctg gattacaacc cgacgggaga
    21421 caaagatgcg ccggtttatg cctgcctggt cggtaaaggt atcacctttg actccggcgg
    21481 ttacagtatc aaacaaagcg cttttatgga ctcaatgaaa tccgatatgg gcggcgcggc
    21541 gacagtaacg ggcgcgctgg cgttcgccat tacccgtggg ctgaataaac gcgtaaaact
    21601 gttcctgtgc tgcgctgata atctgatcag cggcaacgcg tttaaactgg gcgatattat
    21661 tcgctaccgt aatggcaaga atgtcgaagt catgaatacc gatgcggaag ggcgactggt
    21721 actggcggat ggcctgattg acgccagcgc gcaacacccg cggctaatca ttgatatggc
    21781 gacgttaacc ggcgcggcga aaacggcgct gggtaacgac taccatgcgc tattcagttt
    21841 tgacgatacg ctggcggggc gcttgctgac cagcgcggcg caagagaatg agccgttctg
    21901 gcgtctgccg ctggcggagt tccaccgtaa ccaactgccg tctaactttg cggaactgaa
    21961 caacaccggc agcgcgacgt atcccgccgg ggcaagcacc gccgcgggtt ttctgtcgca
    22021 ctttgttgaa aattaccgcg aaggctggct gcacattgac tgttccgcca cttatcgcaa
    22081 agcgccggtt gagcagtggg ctgccggggc aaccggtctg ggtgtgcgca ccatcgcgaa
    22141 tctgctgacc gcctgaacgg tgtttttgta ggccgggtaa gcgaagcgcc acccggcatt
    22201 ttgcctgatg gcgacgccgt gcgtcttatc aggcctacaa cccatataca taatttgtga
    22261 ttcctatgtc cgaaactaaa aatgaattag aaattttgct ggagaaagcg gcgactgagc
    22321 ccgcgcatcg ttcggcattt ttccgtacct tactggagtc caccgtctgg gtgccgggca
    22381 gcgctgccga aggcgaggcg attgtggaag acagcgctct ggatttgcag cactgggaaa
    22441 aagaagacgg cacgaccgtc attcccttct ttacttctct ggaggcgctg cagcaggccg
    22501 tggaagacga acaggcgttt gtggtgatgc cggcgcgcac gctgtttgaa atgacgcttg
    22561 gcgaaacgtt attcctcaac gctaaattgc cgaccggcaa agagtttatg ccgcgtgaaa
    22621 tcagcctgct tctcgctgag gaaggcagtc cgttaagtac gcaggaagtg ctggaaggcg
    22681 gcgagtcgct tattttatcc gaagtggccg agccgccgtc gcagatgatt gattccctca
    22741 ctacgctgtt taaaaccatc aaaccggtga aacgcgcatt tctctgcgcg attaaagaac
    22801 atgcggacgc ccaacctaat ctgctgattg gcattgaggc tgacggcgaa attgaagaga
    22861 tcattcacgc agcgggcaat gtggcgaccg acacgttacc gggtgacgaa ccgatcgata
    22921 tttgtcaggt gaggaagggc gcgcagggta tcagccactt tatcaccgag catatcgcgc
    22981 cgttctacga gcgtcgttgg ggtgggttcc tgcgcgattt taaacagaac cgcatcatct
    23041 gaagaaaaga aagccgccca acagggcggc ctcctggctt acctgctctg gacgttgagc
    23101 gttacgggaa cagaattacc tgggtagctt ctgtctgcgt gaagacacaa cgtgccagaa
    23161 acaagaagca cgacacaaaa gcatcgtacc ttcatgttgc ggtccttgcg aagaccgcat
    23221 cacggcagca ccgctggcga taatgccgtg atagcaggca ctgtggtgtg cctgcgctta
    23281 cggccatgga acatcctctc ctgaagccag tgcccgtttg cgagacggcg aagggggccg
    23341 ggaaagataa tacctcaaat gctgaatagt ttcgtcgtga attaacttga ctttgctctc
    23401 cttaaaaggg agtatttacc tactgtggtg tgcctgcgtt gctatggcaa caaagcctgc
    23461 tggaaaggcc gcgaaccgga ccagcacaaa aaaaccgctc aactgagcgg tttttttgtg
    23521 gcctgcttaa acagtattta tgtagattcg ttttaaatca gcctgaacgg taggccggat
    23581 aagcgtgagc gccacccgac agcatgtcga ttaatcgacg agcgcgtcca gttttgccca
    23641 aaacgcctca tgataatcct ccaggtcaag taaagcggca tcgcgttgtt cattcatttt
    23701 ttgctgtgcc ttccattgcg gaagatgtaa atcctcttcg gtaaagccaa tgtctttagc
    23761 gcccgaaata atattataga gatattccac cagagaagac tccgccagcc aaaattcatt
    23821 acgttccatg cgggcaatag ggtattcgcc gttggcatcc cgttctgtga tatagataaa
    23881 aatggcctga tcgccgacat gatcaatacg aattaatgcc ggaagacggg gatcgttact
    23941 ccagacaggc atcagatctt caatatcaat acctgagcta tccatgccag cgccgtaata
    24001 cgcctcttca tcaggagagt aagaatgtat tactccctcg ttatcaataa atctttgtaa
    24061 tgtttcaatc acaggcatat tataattgct aagtagatcg cggtcgtagg ccagtagcgc
    24121 cttcaggctt
//
LOCUS       DAJVKX010000060        24046 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000060 DAJVKX010000000
VERSION     DAJVKX010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24046
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.060"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..431
                     /gene="tviA"
                     /locus_tag="OPY25_002501"
     CDS             <1..431
                     /gene="tviA"
                     /locus_tag="OPY25_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001210944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis regulator TviA"
                     /protein_id="HCS0928096.1"
                     /translation="NLNRYSLLNALNFFTRMSDINKIIVIISSSRLMPLARFWLTECK
                     NVIAVFDAATSVQDIIRNVSQHQSGEKILTEQRDYRFRINRKDIVKMKYFLSESGMEE
                     LQDRFMNSSSTMYRWRKELAVKFGVREPRYLLLPDSVTLL"
     gene            676..1953
                     /gene="tviB"
                     /locus_tag="OPY25_002502"
     CDS             676..1953
                     /gene="tviB"
                     /locus_tag="OPY25_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosamine C-6 dehydrogenase TviB"
                     /protein_id="HCS0928097.1"
                     /translation="MFGIDEVKIAIIGLGYVGLPLAVEFGKSRQVVGFDVNKKRILEL
                     KNGVDVNLETTEEELREARYLKFTSEIEKIKECNFYIITVPTPINTYKQPDLTPLIKA
                     SETVGTVLNRGDIVVYESTVYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGD
                     KKHRLTNIKKITSGSTAQIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLN
                     IALVNELAIIFNRLNIDTEAVLRAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKSQGI
                     GYYPEIILAGRRLNDNMGNYVSEQLIKAMIKKGINVEGSSVLILGFTFKENCPDIRNT
                     RIIDVVKELGKYSCKVDIFDPWVDAEEVRREYGIIPVSEVKSSHYDAIIVAVGHQQFK
                     QMGSEDIRGFGKDKHVLYDLKYVLPAEQSDVRL"
     gene            1956..3002
                     /gene="tviC"
                     /locus_tag="OPY25_002503"
     CDS             1956..3002
                     /gene="tviC"
                     /locus_tag="OPY25_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosaminuronic acid C-4 epimerase TviC"
                     /protein_id="HCS0928098.1"
                     /translation="MTAYEELRTKLVLAPKRWLITGVAGFIGSGLLEELLFLNQTVIG
                     LDNFSTGYQHNLDDVRTSVSEEQWSRFIFIQGDIRKFTDCQKACKNVDYVLHQAALGS
                     VPRSLKDPIATNSANIDGFLNMLTAARDAHVSSFTYAASSSTYGDHPDLPKIEERIGR
                     PLSPYAVTKYVNELYADVFARSYEFNAIGLRYFNVFGRRQNPNGAYSAVIPRWILSLL
                     KDEPIYINGDGSTSRDFCYIENVIQANLLSATTNDLASKNKVYNVAVGDRTSLNELYY
                     LIRDGLNLWRNEQSRAEPIYKDFRDGDVKHSQADITKIKTFLSYEPEFDIKEGLKQTL
                     KWYIDKHSTLYSSV"
     gene            3026..5521
                     /gene="tviD"
                     /locus_tag="OPY25_002504"
     CDS             3026..5521
                     /gene="tviD"
                     /locus_tag="OPY25_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis protein TviD"
                     /protein_id="HCS0928099.1"
                     /translation="MNLMKSSGIFTLTAIGSCRIVSPVKRAQPYFNFQANFKRIYGFT
                     HTSSEALQQIRFILGLIDIPEKVRPFIFRPNVNYSNTDVHSRSDFYIIEISSQKKIMA
                     YGFCLQINYLTRHFYEFFSQTERACMYWSLATQGNRHKLLAYLKDDPCFAGMSEDDRA
                     LLSNINVEQMDEHAIEQDMMEIVQLLSRDRVMFMTHVDAVTRAGTVIPSRSRLIKNVD
                     TIAARMDIPCVNPTNLMEKWGQKRALEKNGDDLTHYTDMFGDAIVAAIFKGVINNTNH
                     HLDEGRQEKQDQIREITLSITKQLADGDIIAASQQLFAALRNQQQDPVLIQLRSVIFS
                     HLGYYEQAYQDISDVEKIIGTTDSTLRCRLRSLHGLARWREALSTAEMMLSNEIEDEE
                     VLTVAAGSADALQLFDKSYHYWKRVLLLNPETQSGWVNFLSSTQYFNDGNAFSEAFHA
                     GIQSQRLNDTFMETALSLAIKFSDELIFMHALEQLLRHESEFALTVLSTIHDTGLVIR
                     TAFCIKNMSYHQALRTSYKDKIHDVFEAWNNTALSLHSVDDFVSLSTSLAYSYSAFMV
                     YPHSRISRFNNEVKMAWRDKLREMYEREDYENILAGAKIVWPLLKFDPVGTVYCARTL
                     VNLGAWKDACTLAHMTLIRNSNITSLQSIMLRSIRHINNIPFLIDLIANVMSITLSFQ
                     NASMNKLFEKECRNVATRALKYVRQKKTEGRLDEALSVLISLKRIEPDVSRLMREYKQ
                     IIRLFNESRKDGGSTITSYEHLDYAKKLLVFDSENAYALKYAALNAMHLRDYTQALQY
                     WQRLEKVNGPTEPVTRQISTCITALQKNTSGKS"
     gene            5521..7257
                     /gene="tviE"
                     /locus_tag="OPY25_002505"
     CDS             5521..7257
                     /gene="tviE"
                     /locus_tag="OPY25_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     glycosyltransferase TviE"
                     /protein_id="HCS0928100.1"
                     /translation="MITQEEKLAALGKTCLTLKQEKKLAQAVALIDSELPTEALTSLA
                     MLKKAEFLHDVNETERAYALYETLIAQNNDEARYEYARRLYNTGLAKDAQLILKKVSN
                     GVQKKYNNYLGKINKICDLLERLEGKAIPVGTNTCIIAMKHAILFYRNRQPRQLPVGS
                     FGRLALCTGSLGSGGAERQISRLAIEIARKYRQKGKIGGLKVEEPVELIIRSLTPELR
                     QDFFLKEVLEEQVEVLEIAKITGNLFDDATIESPELRLLLSHLPPVCKYGIKHLVPHL
                     CERKLDYLSVWQDSACLMIALAALIAGVPRIQLGLRGLPPVVRKRLFKPEYEPLYQAL
                     AVVPGVDFMSNNHCVTRHYADWLKLEAKHFQVVYNGVLPPSTEPSSEVPHKIWQQFTQ
                     KTQDADTTIGGVFRFVGDKNPFAWIDFAARYLQHHPATRFVLVGDGDLRAEAQKRAEQ
                     LGILERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTPAGGSA
                     ECFIEGVSGFILDDAQTVNLDQACRYAEKLVNLWRSRTGICQQTQSFLQERFTVEHMV
                     GTFVKTIASQPR"
     gene            7302..8369
                     /gene="vexA"
                     /locus_tag="OPY25_002506"
     CDS             7302..8369
                     /gene="vexA"
                     /locus_tag="OPY25_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter protein VexA"
                     /protein_id="HCS0928101.1"
                     /translation="MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPT
                     LKLSAPDTVPKTIVDPVFAANNWHWTSLAKGDVLHITILSSGGAGYLSNNASGDRADF
                     ENILVTDSNTVQVPYAGTIPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMV
                     TVEGSGKTGRYPLEQSMNRLSHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQ
                     YPGLDIALQPDDRITLRQVTEYVNVLGAAGVQGKHALVQRHSSVVDALALAKGLNDNL
                     ADPQAIFLYKHNEAEQAKQQMRKLNIYHVDMSQPNSVFLAQAIRVDNGDVIYISNASL
                     TDFAKVKAAFDSFLTRGTNSF"
     gene            8379..9173
                     /gene="vexB"
                     /locus_tag="OPY25_002507"
     CDS             8379..9173
                     /gene="vexB"
                     /locus_tag="OPY25_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001023498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter inner membrane
                     protein VexB"
                     /protein_id="HCS0928102.1"
                     /translation="MNILKNNSYYFMKLITVCELIILLMSRDIKTRYNGNLLNYMMVL
                     AVPLVWISITVISFQYLNRSVPISTDDISFVIAGILPYLLFRYTITATMRTHSFSTSL
                     AVVSQVKKRHVIFSLAAIEFVNAVIIYIIISLINFLIFSRWEAQKPFLIFEGMVIAWL
                     LGLSFGYFCDALSERFPLVYKAVPVMLRPMFLISAVFYTANELPYSLLSIFSWNPLLH
                     ANEIVREGMFEGYHSLYLEPFYPLAFSATLFLAGLIFHLICDTENH"
     gene            9199..9894
                     /gene="vexC"
                     /locus_tag="OPY25_002508"
     CDS             9199..9894
                     /gene="vexC"
                     /locus_tag="OPY25_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter ATP-binding
                     protein VexC"
                     /protein_id="HCS0928103.1"
                     /translation="MFGLLGCTRYFESDKGPRVVLDKTDFVMGYHEHIGILAAPGSGK
                     TTLTRLLCGLDAPDEGDFIGLRGDALPLGANSFILPGLTGEENARMMASLYGLDGDEF
                     SHFCYQLTQLEQCYTDRVSEYSVTMKTHLAFAINLLLPCRLYIADGKLYTGDNATQLR
                     MQAALACQLQQKGLIVLTHNPRLIKEHCHAFGVLLHGKITMCEDLAQATALFEQYQSN
                     QATIQTEDYSFDI"
     gene            9917..11221
                     /gene="vexD"
                     /locus_tag="OPY25_002509"
     CDS             9917..11221
                     /gene="vexD"
                     /locus_tag="OPY25_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000431675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter inner membrane
                     protein VexD"
                     /protein_id="HCS0928104.1"
                     /translation="MENSERIKKWKEERAKVAQESRASRLQQKEDERALRQTEKSADA
                     KSHHNPDAGWSATDADSVRRASLVIKERRVQQAKQSLRRLFLYIALPLLVIMLMSWIL
                     TSHFYSADATFIVQTDASQDNFSGTSFFGAGNKMSEGFQVREFILSKEMMDRMEKELG
                     FLSYFAQDDIALFSRFHAPLGINDDPYRYYLSKVSVAVDIQQGMLRLNVKARSAKQAE
                     FFAQRILSFAEQHVNTVSARMQKERILWLENDVKSAQENLGAARLELLKIQHIQKDID
                     PKETITAIYQLIAGFETQLAEAKAEYAQLMVNGLDQNPLIPRLSAKIKVLEKQIGEQR
                     NRLSNKLGSQGSSESLSLFEDLRLQSEIAKARWESALQTLQQGKLQALRERQYLLIIS
                     QPMAESDTTRYADGTKWLLFFVLLGITYLVTSLLITIRRMRE"
     gene            11241..13211
                     /gene="vexE"
                     /locus_tag="OPY25_002510"
     CDS             11241..13211
                     /gene="vexE"
                     /locus_tag="OPY25_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide transport protein VexE"
                     /protein_id="HCS0928105.1"
                     /translation="MSLHSTFKKISPTTLLKQEDWEGLCLYFSQHPEKVRDSAGNEQN
                     IILFAIACLRKDETDVGLTLLSDRVLTAKNGRDLLRRWVISPLASSQPDAVLQVVNKL
                     LAVNVCQPEDVLLVASVLLKSKQYATVADLAEQAWLAFSGNSQIFALHLRTLVLMDKE
                     LQAISLARTQAQEVPPRGDMIATCLSFLNKSRLPEDHDLARALLPFFALERQESAGLA
                     VDTLCAVGKYQEAIQTGESALARGLDGAALRRSLGLAYYQSGRSREAKLQAAEHWRHA
                     LQFNSDNVRIVTLYADALIRTGQNEKAIPLLQQSLATHPDLPYVRAMYARALRQVGQY
                     TAASDEFVQLAREKGVTSKWNRYAAAALLQAGKTSEAESVFEHYIQARASHLPQSFEE
                     GLLALDGQISAVNLPPERLDWAWEVAGRQSGIERDEWERRAKWGYLADNFLLDWLECR
                     GEQADEPMYRLADISHVEQFFQRLQLDQRGCIIVSAHLGAMYAGPMILSLLEMNSKWV
                     ASTPGVLKGGYGERLISVSDKSEADVVRACMQTLHSGQSLVVAIDGALNLSAPTIDFF
                     GQQITYSTFCSRLAWKMHLPTVFSVPIWKNRHIHFVLERMVDPLKFESQLSFTERWKE
                     NYLQCVTRILQSDPENLRLSGGIWRNIIRRDS"
     gene            complement(13513..14259)
                     /locus_tag="OPY25_002511"
     CDS             complement(13513..14259)
                     /locus_tag="OPY25_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCS0928106.1"
                     /translation="MDIPRIFTISESEHRIHNPFTPEKYATLGRVLRMKPGMSVLDLG
                     SGSGEMLCTWARDYGITGTGIDMSPLFTAQAKLRAEELGVSERVHFVHNDAAGYVADE
                     QCDIAACVGATWIAGGVAGTMNLLAMSLKPGGIMLIGEPYWRQVPPTEEIAQACGVSS
                     VADFLTLQGLVASFDERGYDLVEMVLADQEGWDRYEAAKWLTMRRWLEDNPDDDFVQE
                     VRKELTVAPKRHVNYTREYLGWGVFALMAR"
     gene            complement(14259..15149)
                     /locus_tag="OPY25_002512"
     CDS             complement(14259..15149)
                     /locus_tag="OPY25_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCS0928107.1"
                     /translation="MDISTLISSSGRLQLSAAESKIPWEELAFSQRMLENHLSQDHDW
                     ASRRQIVIEQQVGWIARQLLVGARILDIGCGPGLYTHLLAERGYCCTGVDFSPASIEW
                     ARQQAQTAGLSIDYIRQDIRTYWPETQFEFIMMTFGELNVFSATDAQTLISRCARWLV
                     PGGRLFVEVHTFDEVKRQGMAPASWQRCPHGLFLAASHLLLTENAWDEETQTSSTQFW
                     AIDENGRISRFGSQMTAWRDDEYASLLGNAGFKILSHPDSSEWPVSETFEGKLFALLA
                     EKSKSPEGRSLNTQLKKGVN"
     gene            complement(15160..15417)
                     /locus_tag="OPY25_002513"
     CDS             complement(15160..15417)
                     /locus_tag="OPY25_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjhX family toxin"
                     /protein_id="HCS0928108.1"
                     /translation="MNLSRQEQRTLHVLAKGGRIVHVRDASGRVTSVECYSREGLLLA
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRSQPDNR"
     gene            complement(15719..15829)
                     /locus_tag="OPY25_002514"
                     /pseudo
     CDS             complement(15719..15829)
                     /locus_tag="OPY25_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310150.1"
                     /note="with lsrACD is involved in the transport of
                     autoinducer 2 into the cell; incomplete; partial in the
                     middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein"
     gene            16064..16408
                     /gene="umuD"
                     /locus_tag="OPY25_002515"
                     /pseudo
     CDS             16064..16408
                     /gene="umuD"
                     /locus_tag="OPY25_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549365.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
     gene            complement(16524..17549)
                     /locus_tag="OPY25_002516"
     CDS             complement(16524..17549)
                     /locus_tag="OPY25_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCS0928109.1"
                     /translation="MSIRKQPNGKWLCECYPNGRDGKRVRKQFATKGEAIAFENHTMD
                     EVNKKPWLGEKEDRRHLSEVIEQWHSLYGQTLADPKRLLAKLSIICNGLGDPIASELT
                     AGDFTKYREARLKGEVKNEDGVLMSPVKPRTVNLEQRNLSSVFGTLKKLGHWPAPNPL
                     AGLPTFKIAEGELAFLAPEEIKRLLDACADSQSPSLLMIAKICLATGARWSEAENLQG
                     HQLSKYRITYTKTKGKKNRTVPISQELYDELPKNRGKLFTPCRKSFERAVKRAGIELP
                     EGQCTHVLRHTFASHFMMNGGNILVLRDILGHADIKMTMVYAHFAPDHLEDAVTKNPL
                     HNLNWKR"
     gene            complement(17553..18185)
                     /locus_tag="OPY25_002517"
     CDS             complement(17553..18185)
                     /locus_tag="OPY25_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0928110.1"
                     /translation="MSLIKAGNDSGGRDAINRLIKAYNFSSRQQLCEHLEVSKSTMAN
                     RYLRDSFPAEWVIQCALETGISLLWLATGQGDMYACENEERNLKNETSVTVRPLSKIV
                     APSIKHVELKNGELQPSDEILLDSRLLDGDSSNSLFVKTATDSFVVDTSVKQVSNGFW
                     LVDMDGVKSIVKIARVPGNKIVVHQDETSFECSVDDIEAIGRAVKVIKSL"
     gene            18302..18544
                     /locus_tag="OPY25_002518"
     CDS             18302..18544
                     /locus_tag="OPY25_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HCS0928111.1"
                     /translation="MSTDISIRVPKEMATPAEFAEWEGISRGSVYQKIHHGQLAKYMV
                     KKEKNKGRVSLRYLMYKTDQVRESLGHSNFRVIVGQ"
     gene            18577..19086
                     /locus_tag="OPY25_002519"
     CDS             18577..19086
                     /locus_tag="OPY25_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory CII family protein"
                     /protein_id="HCS0928112.1"
                     /translation="MFDYKISKHPHFDEACRAFALRHNMAKLAERAGMKVQTLRNKLN
                     PEQPHQLTPSEIWLLTDITEDSTLVDGFLAQIHCLPCIPMNEVAKEKLPHYVMSATAE
                     IGRVAAGAVSGDVKTTAGRRDVISSINSVTRLMALAAVSMQARLQANPAMASAVDTVT
                     GLGASFGLI"
     gene            19094..19294
                     /locus_tag="OPY25_002520"
     CDS             19094..19294
                     /locus_tag="OPY25_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2724 domain-containing protein"
                     /protein_id="HCS0928113.1"
                     /translation="MLTKEPSFASLLVKQSPAMHCGHGWIMGKDGKRWHPCRSQDALL
                     AELSAKKQGKPWLLKVMLRLFR"
     gene            19258..19599
                     /locus_tag="OPY25_002521"
     CDS             19258..19599
                     /locus_tag="OPY25_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5347 domain-containing protein"
                     /protein_id="HCS0928114.1"
                     /translation="MAIEGDAATVPLSAGLRLNGLNHIAELRAKVFGLNIDSELDRFI
                     SDMRDQRDINHEQNKRALAAIFFMAKIPAERHSVNVSELTTDEKRELIKAMNHFRTVV
                     SLFPNRLAMPN"
     gene            19667..19900
                     /locus_tag="OPY25_002522"
     CDS             19667..19900
                     /locus_tag="OPY25_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 domain-containing protein"
                     /protein_id="HCS0928115.1"
                     /translation="MRNIETRITKTGPDDAGLNQMLTDARMEERRGRADVMAARLDSL
                     AARIVSRQLNHTEAAELLRQEAVKIQNEAQEIH"
     gene            19900..20127
                     /locus_tag="OPY25_002523"
     CDS             19900..20127
                     /locus_tag="OPY25_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HCS0928116.1"
                     /translation="MADSMDLVQQRVEEERQRHIHTARNKTPGVSRVLCIDCDAPIPP
                     ARRRAIPGVQCCVTCQEIAELKGKHYNGGAV"
     gene            20124..20708
                     /locus_tag="OPY25_002524"
     CDS             20124..20708
                     /locus_tag="OPY25_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HCS0928117.1"
                     /translation="MNTDKMTISQRANQWLDNDYLFIDTETTGLGDDAEIVEICIIDS
                     HGFIMLNTLIKPTKPIPDEAIAIHGITNEMVAFAPAWTDICGAVEELFRRFGFVIYNA
                     DFDLRLIRQTYALNERPSEGAPWMLAAHSVCAMKLYAEYRGEPGRFNGYKWHKLVDAA
                     AHEGVVVEGKAHRALADCKMTLGLVRALAKGGAK"
     gene            20705..21565
                     /locus_tag="OPY25_002525"
     CDS             20705..21565
                     /locus_tag="OPY25_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HCS0928118.1"
                     /translation="MSTILKWAGNKTAIMPELIKHLPAGQRLVEPFAGSCAVMMATDY
                     PHYLVADINPDLINLYKKIALDCEAFISRAKNIFAIANREVAYYNIRHEFNHSSEITD
                     FMKAVYFLYLNRHGYRGLCRYNLSGHFNVPYGNYKNPYFPENEIRAFAKKAQRATFIC
                     ASYDETLAMLRAGDVVYCDPPYDGTFSGYHTASFTGDDQYHLASILERRSSEGHPIIV
                     SNSDTSLTRSLYRNFTRHRIIAKRSMGVAAGDGKSATEIIATKLVRWFGVDLASGPDV
                     SVETEVRAWQ"
     gene            21556..23964
                     /locus_tag="OPY25_002526"
     CDS             21556..23964
                     /locus_tag="OPY25_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HCS0928119.1"
                     /translation="MAVSKITLHYAQTTGGSNEAAAAFPWNTPKKAVNPYLDPAEFAP
                     ESALSNLIALYAVDNEQEQLRRETLSDEVWERYFFNESRDPVQREMEQDRLINHAKTA
                     REQQRFNPDLVIIANVGAQPAHISKPLLERIKYFHSLGRAKAYSRYLQKTIRPCLERL
                     ERVRDSQVSASFRFMASHDGLEGLLVLPEMNQDQVKRLSTLVAAHMSMCLDAACGDLF
                     VSDDVKPEEIRQAWERVAAEAMRLEVIPPAFEQLRRKKRRRKPVPYELIPPSLARMLC
                     ADWWYRKLWQMRCEWREEQLRAVCLVNKKASPYVSYEAVIHKREQRRKSLEFFRSHEL
                     INEDGDTLDMEDVVNASNSNPAHRRNEMMACVKGLELIAEMRGDCAVFYTITCPSRFH
                     ATLNNGRPNPKWTSATVRQSSDYLVDTFAAFRKAMHKAGLRWYGVRVAEPHHDGTVHW
                     HLLCFMRKKDRRSITALLRKFAIREDREELGANTGPRFKPELINPRKGTPTSYIAKYI
                     SKNIDGRGLAKEISKETGRSLRDSAEHVSAWASLHRVQQFRFFGIPGRQAYRELRLLA
                     GQAARVQGERKAGAPVLDNPRLDAVLAAADAGCFATYIMKQGGVLVPRKHHLVRTAYE
                     LNDEPSAYGDHGIRIYGIWSPIAEGKICTHAVKWKKVRKAVDVQEAAADQGACAPWTR
                     TRGNNCPPVENLNKSGGDLPDIKTMNEKELQDYLHNMGQKERRELTARLRLVKPKRKT
                     VYKQNISEQQRLQLEAELTARGFEGSASEIDLLLRGGSIPSGAGLRIFYRNHRLQEDD
                     KWRQ"
BASE COUNT         6274 a         5474 c         5931 g         6367 t
ORIGIN      
        1 tgaacctaaa tcgctacagc ctgttaaatg ccctgaattt tttcacgcga atgagtgata
       61 ttaataaaat aatcgttatc atttcaagtt cgcgactaat gccccttgca cgtttttggt
      121 tgacagagtg caaaaatgtt attgctgttt tcgatgcggc aacatcagtc caggatatta
      181 tcagaaatgt cagtcaacac caaagtggtg aaaagatctt gacggagcag agagattatc
      241 gtttcagaat taaccgtaag gatatagtaa agatgaaata tttcctttcg gaaagtggta
      301 tggaagagct tcaggataga tttatgaact catcatcgac tatgtatcgc tggagaaaag
      361 aattggcagt aaaatttgga gtacgtgagc cgcgctatct gttattgccg gattcagtta
      421 ctttactgta atgcggtaat ttttattgag taaaacacgg acaagtattt cgtttcagca
      481 caaaattatt ttcgttactc attggcgtta atacatatat tctcagcgac ttctgttcta
      541 ttcaagtaag aaaggggtac ggttatacgt tttcattaac catactggct gctacggcca
      601 ggggcggtag cgtatctgaa taaacaccta gaattaactt tgtaaatata aaattttagt
      661 aaaggattaa taagagtgtt cggtatagac gaggtaaaaa tcgcgattat tgggctggga
      721 tatgttgggc ttcctctggc agttgaattt ggcaaatctc gtcaggttgt tggcttcgac
      781 gttaataaaa agcgtattct tgaattaaag aatggggtgg atgtcaatct ggaaaccact
      841 gaagaagaat tacgtgaggc tcgttatctg aaatttactt ccgagattga gaagatcaaa
      901 gaatgtaatt tttacatcat caccgtcccg acgccgataa atacctacaa gcaaccagac
      961 ctcaccccac taatcaaggc gagtgaaacc gttggtacag tgctgaatcg gggagatatt
     1021 gtggtatatg aatctacggt atatccggga tgtaccgaag aagaatgcgt gccgatcctt
     1081 gctcgtatgt ccggaatgac tttcaaccag gatttctatg tcggttatag cccggaaagg
     1141 atcaatcccg gtgataaaaa gcaccgttta accaacatca agaaaatcac ctccggttca
     1201 accgcacaga tcgccgaact tatcgatgaa gtatatcagc agatcatcag cgcaggtaca
     1261 tataaagcag agagcatcaa agttgctgag gcagcgaagg tgattgaaaa tacgcaacgc
     1321 gatctgaata ttgccttggt caatgagctg gcgattattt ttaatcgttt aaatatcgat
     1381 actgaagccg tgctacgtgc cgctggcagc aaatggaatt tcctgccatt ccgtccggga
     1441 ctggtcggtg gtcactgtat tggcgtagat ccctattatc tgacacataa atctcagggc
     1501 attggctatt atccagaaat catacttgca ggacgccgcc tgaacgacaa catgggcaac
     1561 tatgtctccg agcagttgat caaagcaatg atcaaaaaag gaattaacgt tgagggttcc
     1621 agcgtgctga ttctcggctt tacctttaaa gaaaactgtc cggacatcag aaatacacgc
     1681 attattgatg tggtaaagga actcggtaaa tatagttgta aagtggatat ttttgatcca
     1741 tgggtggatg ccgaagaggt aagacgagag tatggcatta tcccggtatc ggaagtcaaa
     1801 tcaagccact acgatgcgat cattgttgca gtaggacatc agcaatttaa acagatggga
     1861 agtgaggata ttcgcggctt cggaaaagat aaacatgtac tttatgattt gaagtatgtt
     1921 cttccggctg agcagtcaga tgtgagattg taatcatgac ggcttacgaa gaactacgga
     1981 ccaaactggt tctggcacca aagcgctggc tgatcactgg cgtagcaggc tttattggct
     2041 ccggcttatt agaagaatta ctctttctca accagactgt cattggactg gataactttt
     2101 ccaccggtta tcagcataat ctagacgacg ttcgcacgtc cgtcagtgag gagcaatggt
     2161 cgcgatttat ttttattcag ggtgacatca ggaaatttac tgactgtcag aaagcgtgta
     2221 agaacgttga ctatgttctc caccaagccg cgctaggaag cgtgccacgt tccctaaagg
     2281 atcccatcgc gactaatagc gccaatattg atggtttttt aaatatgttg acggcggcga
     2341 gagatgctca tgtctctagt ttcacctacg ccgcaagcag tagcacctat ggagaccatc
     2401 ccgatttacc taaaattgag gaacggatcg gtcgaccact cagcccgtat gcggtaacaa
     2461 aatacgtcaa tgaattgtac gctgatgtgt ttgcacgtag ctatgaattt aacgctattg
     2521 gcctacgcta ctttaatgtc tttggtcgcc gccaaaatcc taacggagcg tactcggcag
     2581 ttattcctcg ctggatacta tcgcttctta aagatgaacc aatttatatc aatggcgatg
     2641 gctcaacaag cagggatttt tgctatatag agaatgtgat tcaggccaat ctattatcag
     2701 caacaactaa tgatttagcc tctaaaaata aggtctataa tgtggcagtt ggagatagaa
     2761 cttcgttaaa tgagctttat tatctaattc gcgatgggct taatttatgg cggaacgaac
     2821 aaagtagagc tgaaccaatt tataaagatt ttcgtgacgg tgacgttaag catagccagg
     2881 cagatattac caaaataaaa acatttcttt catatgagcc tgaatttgat atcaaagaag
     2941 gacttaagca gactctaaaa tggtatatcg ataaacattc tactttgtat tcctcggtat
     3001 aactactcac tttcctttca cgtggatgaa tttaatgaaa tcgtcaggga tatttacgct
     3061 tacagccatt ggcagttgcc gtattgtgag tccggtaaaa cgagctcagc cttattttaa
     3121 ttttcaggca aactttaaga gaatatatgg ttttacgcat acgagcagcg aggcattaca
     3181 gcagattcgg tttattttgg gcttgataga cattcctgaa aaggtccgac catttatttt
     3241 tagacctaat gtaaactatt caaacaccga cgtacatagt cgttctgatt tctatatcat
     3301 tgagatttca agtcagaaga agattatggc ctatgggttc tgcttacaaa taaattattt
     3361 aactcgtcat ttctatgaat tttttagcca aacagagcgg gcgtgcatgt actggtcgtt
     3421 ggccacgcaa ggaaatcgac acaaactgct ggcctatctc aaagacgatc cctgttttgc
     3481 cggaatgtcg gaagacgatc gtgccttatt aagcaatatc aatgtcgagc agatggatga
     3541 gcatgctatc gaacaggata tgatggaaat cgttcagctt cttagtcgcg atcgcgttat
     3601 gtttatgaca catgttgatg ccgtgactcg tgctggaacc gtcattccat cccgtagtcg
     3661 gttgattaaa aatgtcgaca ccatcgccgc caggatggat attccctgcg ttaacccgac
     3721 aaatttgatg gaaaagtggg ggcagaaacg agccctggaa aaaaatggcg acgatcttac
     3781 tcattatacc gatatgtttg gtgacgcgat cgttgcggct atttttaagg gagtgatcaa
     3841 taatactaat catcatcttg atgaggggcg acaagagaaa caggaccaaa tacgtgagat
     3901 taccttatcg atcactaagc agcttgcaga tggcgacatt attgctgcat cacaacaact
     3961 ttttgccgca ttaagaaatc agcagcaaga tcccgttcta atccaacttc ggtccgtaat
     4021 cttcagccat ttaggttatt atgaacaggc ttatcaggat attagtgatg ttgagaaaat
     4081 tatcggtacg actgacagta cattacgttg tcggctgagg tctctacatg gattagcgcg
     4141 ttggcgggaa gccttatcga cggcagagat gatgctttcc aatgaaattg aagatgaaga
     4201 agtccttacc gttgccgccg gctcagccga tgctttacag ctgtttgata agtcatatca
     4261 ttattggaaa cgtgtactat tattgaatcc tgaaactcaa agcggatggg ttaatttcct
     4321 gagcagcacg caatatttca atgatggcaa cgcattctct gaagctttcc atgccggcat
     4381 tcaatcgcag cgcctaaatg atacgtttat ggaaacggcg ttatctttgg caatcaaatt
     4441 cagtgatgaa ttgattttca tgcatgcgct cgagcagcta ctccgccatg agtcagaatt
     4501 tgcgctgacg gtattgtcga cgattcatga taccggtctc gttatccgca cagctttctg
     4561 catcaagaat atgagctatc atcaagcgct tcgcacctcg tataaagata aaatccacga
     4621 cgtttttgag gcatggaaca ataccgcgct gtcgctacat tcggttgatg attttgtctc
     4681 actgagtact tcgctagcct atagctactc tgcatttatg gtttatcccc attcacgtat
     4741 ttctcgcttt aataatgaag ttaaaatggc atggcgcgat aaattaagag aaatgtatga
     4801 gcgtgaggat tatgaaaata tcctggcagg ggcgaaaata gtgtggccac ttctgaagtt
     4861 tgatcccgtt ggcaccgtat attgtgcaag aacgctggtg aatcttggtg cctggaaaga
     4921 cgcgtgcacg ttggcccaca tgaccttgat tcgtaactcg aacattacca gcctgcagtc
     4981 gattatgtta cgcagcatac gtcatattaa caacattccg ttcctcattg atttgattgc
     5041 taacgtcatg agcattactc tatcattcca gaatgcctca atgaacaagt tgtttgagaa
     5101 agagtgtcgc aatgttgcaa ccagagccct taaatatgta cgccagaaga aaactgaagg
     5161 gcgtctggat gaagcattgt ctgtattgat tagcctgaaa cgaattgagc ctgatgtttc
     5221 tcgtctgatg cgtgaatata agcaaattat cagattattt aatgagtcac ggaaggatgg
     5281 cggtagcact atcacgtctt atgaacatct agactatgcg aaaaaattac tcgtttttga
     5341 tagcgaaaat gcctatgcct tgaaatatgc cgcattaaat gcaatgcatt tacgcgacta
     5401 cacgcaggct ttgcagtatt ggcagcgact ggagaaagtg aatggaccaa cggagccggt
     5461 gacaaggcag atctcgacct gcataaccgc attacaaaaa aatacatcag ggaagtcgta
     5521 atgattacgc aggaagaaaa gttagctgca ctaggaaaaa cgtgtttaac attaaaacaa
     5581 gagaagaagc ttgcgcaagc tgttgcgtta attgacagtg aattaccgac tgaggcttta
     5641 acttcattag cgatgctaaa aaaagcagag tttcttcatg atgtcaatga aacggagcgt
     5701 gcatacgcgc tctacgaaac gctgattgca caaaacaatg atgaagcacg ttatgagtat
     5761 gcacgtcgtt tatataatac ggggctagcc aaagatgctc agctaattct taaaaaggtt
     5821 agcaatggtg tgcagaaaaa atataacaat tatttaggca aaataaataa gatctgtgat
     5881 ttgcttgaac gccttgaagg gaaagcgatc cctgtgggga ccaacacctg tattattgca
     5941 atgaagcatg ccatcttgtt ctatagaaat cgtcaaccca ggcagcttcc cgtcgggtct
     6001 ttcggtcgtc ttgcgctctg tactggctcg ctaggtagcg gtggtgcaga gcgtcagatt
     6061 tccaggctgg ctatcgaaat cgccagaaaa tatcggcaaa aggggaaaat tggcggcctg
     6121 aaagtagaag aaccggtaga actaattatt cgctccctga caccggaact caggcaagac
     6181 tttttcctga aagaagtgct ggaagaacag gtcgaggttc ttgaaatcgc gaagattacc
     6241 ggaaacttgt ttgacgatgc gacaatagaa tctccagagt tgcgcttatt gctatcgcat
     6301 ctaccgccgg tgtgtaaata cggcatcaag catctggtcc cccatttatg cgagcgcaag
     6361 ctggattatc tctccgtttg gcaggatagc gcttgtctga tgattgcgct tgcagcattg
     6421 attgctggcg tgcccagaat tcaactggga ttacgtgggt taccgccggt ggttagaaag
     6481 cgtctgttca agccggaata tgagcctctc taccaggcgc tggcggtcgt gcctggcgtt
     6541 gattttatga gtaacaacca ttgtgtgact cgccattatg ccgactggct gaagttggag
     6601 gcgaagcact tccaggttgt atataacggc gtcttaccgc catctactga accctcttct
     6661 gaggtgccac ataaaatctg gcagcagttt acgcaaaaaa cccaggatgc ggacacgact
     6721 attggtggcg ttttccgctt tgtaggcgat aagaaccctt ttgcatggat tgattttgca
     6781 gcacgctatt tacaacacca ccccgccacg cgctttgtgc tggtaggcga tggtgattta
     6841 cgcgctgaag cgcagaaacg cgccgaacag ttagggattc tggagagaat actattcgtt
     6901 ggcgcctcgc gtgacgtagg gtattggctg caaaaaatga atgtattcat tttgttttcg
     6961 cgttatgaag ggctacctaa tgtgcttatt gaagcacaaa tggtcggggt gccggtgatt
     7021 tcaacccctg caggtggatc ggcagaatgc tttattgagg gtgtttcggg tttcattctt
     7081 gatgatgcac agacggtcaa tcttgaccag gcttgccgct atgcagaaaa gttggtcaat
     7141 ttatggcgca gcagaaccgg tatttgccaa cagacgcagt catttttaca agaacgcttc
     7201 accgtggaac atatggtggg aacgtttgta aaaaccattg cctctcagcc tcgttaatta
     7261 atgggcatca tttttcagct atttcattta taaaataagt tatgaaaaaa atcatcatat
     7321 tactaacgac atttttcctg ctttcgggat gcactattcc cagggcggta tttaaatcca
     7381 gccttattaa tcaggacgat cctcgttata atctggtcga agtcacgccg acattaaaac
     7441 taagcgctcc cgatactgtg ccgaaaacta ttgtcgatcc ggtttttgcc gcaaataact
     7501 ggcactggac atctttggct aaaggcgatg tgctgcatat cactatttta tcctcgggcg
     7561 gggctggata tttatccaat aacgcgagcg gcgaccgtgc ggattttgaa aatattcttg
     7621 tgactgacag taataccgtt caggtgcctt atgccgggac aatcccggtt tctggattgg
     7681 atgtgacgca actggctgat gagatcaaaa agcgactttc gcgcgttgtc ctgaatcctc
     7741 aggtgattgt gacacttacc gcccgcaccg gagccatggt gacggtcgag ggcagcggga
     7801 aaacgggtcg ataccctctc gaacagagta tgaatcgtct gagtcatctt ttggcaacgg
     7861 cagtggcagt agaaaatacc agcacagata tgatggaagt tcacgtgacg cgccagcagc
     7921 attatttcac tgcgcgactg tcagatattt atcagtatcc cggattggat attgccttac
     7981 agccggatga ccgtatcact ctgcgtcaag tgaccgagta tgttaatgtg ctcggcgcag
     8041 caggtgttca ggggaaacat gctctggttc agcgtcattc cagcgtcgtg gatgctttgg
     8101 cgctcgcgaa aggattaaat gacaatcttg ccgatccgca agcgattttt ctgtacaagc
     8161 ataacgaagc ggaacaggcg aaacagcaga tgcgtaagct gaatatctat catgtcgata
     8221 tgagccaacc taactcggtg tttttagcgc aggccatacg agtggacaac ggcgatgtta
     8281 tctatatctc gaacgcctct ttgactgatt tcgctaaggt gaaagccgca ttcgatagct
     8341 ttttgacccg cggcactaat tctttctaat gtcgccatat gaatattttg aaaaataatt
     8401 cttattattt tatgaaactc attaccgtct gtgagttaat tattttattg atgtcacgcg
     8461 atatcaaaac acgctataac ggtaatttac taaactatat gatggtgctg gccgtaccac
     8521 tggtatggat atccattacc gttatttctt ttcaatattt aaatcgctcg gtgccaatat
     8581 ccactgacga tatcagtttt gttattgcag ggatattacc gtatctgtta tttcgttata
     8641 ccattaccgc aaccatgcga acccattcat tctctacatc gttagcggtt gtctcgcagg
     8701 ttaagaaaag acatgtgatt ttttctcttg ccgcaatcga atttgttaat gcagttatca
     8761 tttatattat tatttcatta attaactttc ttatattctc ccgttgggag gcccaaaaac
     8821 cgttcctgat ttttgaaggg atggttatcg catggcttct ggggttatcg tttggttact
     8881 tttgtgacgc actgtctgaa cggtttccgc tggtctacaa agctgttcct gtgatgctaa
     8941 gaccgatgtt tttgatttcg gctgtctttt atacggcgaa tgaattgcct tattcattat
     9001 taagcatatt cagctggaac cctctactac atgctaatga gatagtcaga gaaggtatgt
     9061 ttgaggggta tcactccttg taccttgaac ctttttaccc tctggcattt tccgcaacgt
     9121 tattcctcgc gggcctcatt tttcacctga tttgtgacac tgaaaatcac tgactttagc
     9181 ttcaggagag acgcattcgt gttcggttta ttaggttgta cacgctattt tgagtctgat
     9241 aagggcccgc gggtggtcct tgataaaaca gattttgtca tgggctacca tgagcatatc
     9301 ggtattctgg cggctcctgg ttcaggcaaa acgacgctaa ccaggttgct gtgtggcctg
     9361 gatgctcctg atgaggggga ttttattggg ctacggggtg atgcgctccc actgggggca
     9421 aactctttta ttctgccagg gttaaccggt gaggagaatg cgcgaatgat ggcaagtcta
     9481 tatggcctgg atggcgatga gttttcacat ttctgttatc aattgaccca gcttgaacag
     9541 tgctataccg acagggtgag tgaatattct gtcacgatga aaacgcatct ggcatttgcc
     9601 attaatttac tgcttccctg ccgcctttat attgctgatg gcaagctgta caccggggat
     9661 aatgccacac agttgcgtat gcaggcggcg ctagcttgtc agctgcaaca gaaagggttg
     9721 attgtgctaa cgcacaaccc tcggcttatt aaagaacact gtcatgcgtt tggcgtactg
     9781 ctgcatggaa aaattacaat gtgtgaagat ttagcgcagg caactgcgct ttttgaacaa
     9841 tatcagtcaa atcaggcgac gattcaaact gaagattatt cctttgatat ataattagta
     9901 aatatacgga tagagtgtgg aaaattcaga acgtattaaa aaatggaaag aagaaagagc
     9961 gaaggtagca caagaaagcc gagcctcgcg gctacaacaa aaagaggatg aacgcgccct
    10021 tcgccagacg gaaaaatcgg ccgatgcaaa aagtcatcat aacccagacg ccgggtggtc
    10081 tgcgacggat gctgattctg tccgtagagc gtcattagtt attaaagagc gacgtgttca
    10141 gcaagccaag caatcgctac gtcggctctt tctttatatt gctttgccgc tgctggttat
    10201 tatgcttatg tcgtggattt taacatcgca tttttatagt gcggatgcca cctttattgt
    10261 gcaaactgat gccagccagg ataatttttc tggaacatct ttctttggtg caggcaataa
    10321 gatgtcggag ggctttcagg ttcgcgagtt tatactttcg aaagaaatga tggatcggat
    10381 ggaaaaagag ctcggttttt tatcttattt cgcgcaagac gatatcgcat tattttcccg
    10441 cttccacgcg ccgctgggta ttaatgatga tccttatcgt tactatttat caaaagtctc
    10501 ggttgctgtc gatattcaac agggcatgct gcgtttaaac gtgaaggcac ggagtgcgaa
    10561 acaggctgag ttttttgccc agcgcattct gtcttttgct gaacagcacg ttaataccgt
    10621 ttcagcgcgg atgcagaagg aacggatttt gtggctggaa aatgatgtta aatcggccca
    10681 agagaatctg ggggcagctc gacttgaatt gctaaaaata cagcatatac aaaaagatat
    10741 tgacccgaag gaaaccataa ccgctattta tcaattaatt gctggctttg aaacgcagtt
    10801 ggcggaggcg aaagcggaat acgcgcaatt aatggtgaat ggtttggatc agaaccccct
    10861 tattcctcgc ctgtcggcca aaatcaaggt actggaaaag cagatcggcg aacaacgtaa
    10921 ccgcttgtca aataagttag ggtcgcaagg ctcttcagaa agcctgtcct tatttgaaga
    10981 tcttcgcctg cagagcgaga tcgccaaagc acgctgggaa tctgccttac agaccttaca
    11041 gcaagggaag cttcaagctc tacgtgagag acagtatttg ctgatcattt ctcaaccgat
    11101 ggctgagtct gacaccactc gctatgccga tggaacaaag tggttactgt tcttcgtgtt
    11161 gctgggcatc acgtacctgg tgacttctct cctgataacc atcaggcgga tgcgtgaata
    11221 aggctgagta aggaaatata atgagcttgc actctacatt taaaaaaata tcgccaacca
    11281 ccctactcaa acaagaggat tgggaggggc tatgcctcta tttcagtcag catcccgaaa
    11341 aagtgcgaga tagtgctgga aatgagcaaa acattattct cttcgctatc gcgtgtttgc
    11401 gtaaagatga aacagatgtc gggctgactt tgttgtctga ccgtgtgctg acggcaaaga
    11461 atggccgtga tttattacga cgctgggtta tttcgccact ggcatcatct caaccggacg
    11521 ctgtactaca ggtagttaat aaactgctgg cggtgaatgt gtgccagccg gaggatgtcc
    11581 tgctggtcgc gagcgtgctg cttaagagta aacaatatgc gactgttgct gacttagccg
    11641 agcaggcatg gctcgctttt tcgggaaata gccaaatttt tgccctccat ttgcgcacac
    11701 tggtactgat ggataaagag ttacaggcaa tctcgttggc cagaacacag gcgcaggaag
    11761 ttcccccacg gggagatatg attgcgacct gcctcagttt cttaaataaa agccgcctac
    11821 cagaagatca tgacctggcc cgcgcattgc tccctttctt cgcgttagaa aggcaggagt
    11881 cggcggggct ggcggttgat acgctgtgcg ctgtcggtaa atatcaggaa gccattcaga
    11941 caggggaatc cgcattagcc cgtgggttgg atggtgcagc actgcgtcgt agcctggggc
    12001 ttgcttacta tcaatccggt cgcagtcggg aagcgaagct tcaggccgct gagcattggc
    12061 gtcatgccct gcaatttaac tctgataatg tacgtatcgt gaccctgtat gccgatgcct
    12121 taatcagaac gggtcagaat gagaaagcca ttccgttact gcagcagtcg ctcgcgactc
    12181 atcctgatct tccttatgtc agagcaatgt atgcccgagc actgcgccag gttgggcaat
    12241 acactgctgc cagcgatgag tttgtacaac tggcaaggga aaaaggggtg acgagtaaat
    12301 ggaaccgtta tgccgcggcg gcattgttac aggcggggaa aacaagcgaa gcggaaagcg
    12361 tctttgagca ctatattcag gccagagcaa gtcatctgcc tcaatcattc gaagaggggc
    12421 tgctggcgct tgatgggcaa atatctgccg ttaatctacc gcctgagcgc cttgactggg
    12481 catgggaagt tgccggcaga cagtccggta tcgagcgcga cgaatgggaa cgccgggcga
    12541 agtggggcta tcttgctgat aattttctcc tcgactggct tgaatgtcgg ggagagcagg
    12601 ctgatgaacc tatgtaccga ttggccgaca tatcgcatgt cgaacagttt ttccaacggc
    12661 tacaactcga tcagagaggc tgcattattg tatcggctca tctgggcgca atgtatgccg
    12721 ggccgatgat cctgtcctta ctggagatga acagcaaatg ggtggcttcc actcctggcg
    12781 tgctcaaagg gggctacggc gagcgattga tttcggttag cgataaaagc gaagcggacg
    12841 tggtcagggc ctgtatgcag accttacata gtggacagtc gcttgtggtg gcaatagacg
    12901 gcgcgctgaa tttgagtgcg ccgactatcg actttttcgg tcagcaaatc acctactcca
    12961 cattttgctc tcgtcttgcc tggaaaatgc atttgcctac cgttttcagt gttccgatat
    13021 ggaaaaacag gcatatccat tttgtgcttg agaggatggt cgatccgctg aaatttgaaa
    13081 gccagctttc atttaccgaa cgttggaagg agaattatct gcagtgtgtt acccggatcc
    13141 tgcaaagcga tccggaaaat ctgcgtcttt ccggtgggat ttggcgaaac attatacgta
    13201 gggatagtta ataagcgatt taattgcggt agatgaaaat ttgtacttca gagctgaaaa
    13261 tgtggtatta acccagatat cagtctgcaa gttgcaagtc accatcagta gcacaacgag
    13321 tcccctcaaa caggctgtct gccatgcctt tgactctgtt atatattttt cagcttctgt
    13381 cagccttgca tctcataaaa cattcctgac atttatatta gggccctatc ccaattcgtg
    13441 tttttgaaca ttgcccctcc ctgaatcata ttccccccgg cagctttaat ctaccagggg
    13501 gatccttatt cgctagcgtg ccattaacgc aaagacaccc cagcctaagt attcacgtgt
    13561 gtaattgaca tggcgtttgg gcgcaacagt cagctccttt cggacttcct gtacaaaatc
    13621 atcatcaggg ttatcctcca gccagcgacg catggttagc catttcgccg cctcgtatct
    13681 gtcccagcct tcctggtctg ccagaaccat ttccaccaga tcatagcccc gctcgtcaaa
    13741 agaggctaca aggccctgca gggtgaggaa gtctgccacg gatgagacgc cacaagcctg
    13801 agcaatctct tccgtcggag gtacctgacg ccagtatggt tcaccgataa gcataattcc
    13861 tcctggcttc agactcatgg ccagaaggtt catcgtccct gcgacgccgc ctgcaatcca
    13921 agttgcgcca acgcaggccg cgatatcaca ttgttcatcc gcgacgtaac ccgccgcgtc
    13981 attatgcaca aaatgaacgc gttcactgac accgagctct tctgctcgta acttggcctg
    14041 cgcagtaaaa agtgggctca tatcgatgcc tgtaccggta ataccgtaat cgcgtgccca
    14101 ggtgcaaagc atctcacccg agccgctgcc caaatcgaga acgctcatgc ctggtttcat
    14161 gcgcaacacg cggcccagcg tggcgtattt ttccggcgtg aacgggttat gaatgcggtg
    14221 ttcgctttcg ctgatagtaa aaatacgtgg aatatccatt aatttactcc tttttttagc
    14281 tgtgtattca gggaacgccc ttccggggat tttgattttt ctgccagcag agcaaagagc
    14341 ttgccctcaa aagtctcgct gaccggccac tcgctactgt ccgggtgtga tagtattttg
    14401 aagcccgcgt taccgagcaa actggcatat tcgtcatcgc gccaggccgt catctgactg
    14461 ccaaaacggc taatgcgacc gttttcatct atcgcccaga actgcgttga gctggtctgc
    14521 gtttcttcat cccaggcgtt ttccgtcagc agcagatgag atgccgcaag gaacagtccg
    14581 tgcggacaac gctgccagct cgccggcgcc ataccctgac gtttaacttc atcaaaagta
    14641 tgaacttcaa caaacagcct gccgcctggt accagccacc gggcacagcg gctgataagg
    14701 gtctgagcgt cagtggcact gaaaacattt agctctccaa acgtcatcat gatgaactcg
    14761 aactgtgtct ccggccagta ggtgcgaata tcctgccgga tgtagtcaat gctcagaccg
    14821 gcggtttgcg cctgctgacg agcccactcg atggatgccg gtgaaaaatc aacgcccgta
    14881 cagcaatatc cacgctccgc cagcaagtgg gtgtataaac ccgggccgca gccgatatcc
    14941 agaatgcgtg caccaaccag tagctgacgg gcaatccacc caacctgctg ttcaattacg
    15001 atctgtctgc ggctggccca gtcatgatcc tgcgacagat ggttttccag catgcgctgg
    15061 ctaaacgcca gctcttccca gggtatttta ctttcagctg cagacagctg cagccgaccg
    15121 gaggaagaaa tgagagtact gatatccata atgctctcct taacggttat cgggctgtga
    15181 gcgaacgttg ttcagcccgg tggtgttgat gcggtaaggc tgaccgttga cggacttgat
    15241 cagttttttg gttttgagct ttttgaaaac ggcgagagta cagtcggcga gcaacagccc
    15301 ttcgcggctg tagcattcaa cagaggtaac gcgaccagaa gcatcgcgaa cgtgcacaat
    15361 acgtccacct tttgcgagca catgtaaggt acgctgttcc tgacgggata aattcatact
    15421 ggaaaacctg ttaatcaaca tgagcaaaaa cgagccaaca tccgcagatg ttcgcgtaaa
    15481 gtttaagcgc agcgataatc agtccgttct gagcagaaca gaaaactgat tatctgatga
    15541 ttacattctc cagcatcaaa gcctcggtga gagttgaaag gtatttacgg catgaataat
    15601 aacaactgtt ttttgtaatg aaaacacagg agagaaaaaa tgtgatgcgg gaggaaattt
    15661 cagaaggtaa tgctggcgac ttttattgcc agtaagtgaa cttgtcagcc cgcattaggt
    15721 tctgatcggt cgcggtcgga ctggaaaaga agaaggccac tttggctttc tcttttttga
    15781 cctcatttgc ggccatatcg accagtatgc cgcctaactg tgcagggctt gtgggagacg
    15841 tcggtgttct ggtagctcag accggttatc ccccgctaaa acttatctgc gtacgcttat
    15901 atcagtactg tgggctctgc attgttcagt attaaagact actttggagt aaactttaat
    15961 tcccgttgct tcagccactt atcagaaaaa tcctgtcatc gatttgaacg tggaaactta
    16021 tacctgcata ctgtatatac atacagttat tttgaggtat aacatgctgc actttattcc
    16081 catagcatcc attcctgaag cactgacaat ccctttgttt acagagagat gtgctgccgg
    16141 ttttccttct ccagcaactg actatacaga agaagagctg gatctgaatg cgtattgtat
    16201 acgtcgcccc agttcaactt tctttgttcg ggccattggt gattcgatgc gggatatggg
    16261 gctgcattcc ggtgatctaa tggtggtcga taaagccgaa aagccgctac agggtgacat
    16321 cgtcattgca gaaacagaag gtgagtttac agtcaaacgt ctgcaactta agccccgcat
    16381 cgccctgctt cccatgaatc ctgcatacca tttttagtat agttaaaaca gtgttttatg
    16441 tttaaaaaca gcgagttagt attattaagt atttgtccgt tttacgcgtt tttaatgccc
    16501 tgccgccaaa atgccgccat aaattagcgc ttccaattga ggttgtgaag cgggtttttt
    16561 gtcacggcat cttcgaggtg gtcaggggca aagtgagcgt aaaccatcgt catttttata
    16621 tcggcatggc ccagaatatc gcgcagtacc agtatgtttc cgccgttcat cataaaatgg
    16681 ctggcgaatg tatggcgcag tacgtgagtg cactggcctt ctggcagttc gataccagct
    16741 cgctttactg cacgctcaaa ggattttctg catggcgtga ataacttccc cctgttttta
    16801 gggagttcat catacagttc ctgagatatt ggcacggttc ggtttttctt gcctttggtc
    16861 ttggtataag tgatgcggta ttttgatagc tgatggccct gcaggttttc ggcttcactc
    16921 catcgggcgc cagttgccag gcatattttt gcaatcatca gcaaactggg actctgcgaa
    16981 tcagcacagg catccagtag acgtttaatt tcttccggtg ccaggaacgc cagttcgccc
    17041 tctgcgattt tgaatgttgg cagcccagcg agcgggttgg gtgctggcca gtggcccagc
    17101 tttttcagtg tgccaaaaac agatgatagg ttacgttgtt caaggtttac cgtacggggc
    17161 ttaactggcg acataagcac gccatcttca ttttttactt caccttttaa ccgtgcttcc
    17221 cggtatttcg taaaatcgcc tgcggttaac tctgaggcaa tgggatcgcc caaaccatta
    17281 caaataatgc tgagttttgc caacaggcgt ttggggtctg ccagcgtctg cccataaagt
    17341 gaatgccact gctcaatcac ttctgacaaa tgccgccgat cttctttctc ccccagccac
    17401 ggttttttgt tcacctcatc catggtgtgg ttttcgaatg ctatggcctc gcctttagtc
    17461 gcaaattgct tgcgtacacg cttgccatcc cgtccgttcg ggtagcattc acacaaccat
    17521 tttccgttag gctgttttct gatgctcata agttagaggc tcttgattac tttgactgca
    17581 cgcccgatag cttcaatgtc gtcgaccgag cattcaaatg atgtttcatc ttggtgaact
    17641 acaattttgt tgcctggaac gcgagcgatt ttgacgatgc ttttaactcc gtccatatcg
    17701 actaaccaga agccattact gacttgttta acagacgtat ccacaacaaa gctatcagta
    17761 gctgttttta caaacaaaga gttggatgag tcaccatcga gcagtctgct atcaagaaga
    17821 atttcatcac ttggctgcag ttcaccgttc ttcagttcaa catgtttgat gctaggagca
    17881 acaattttag aaagtggtct taccgtgacg gaggtttcgt ttttgagatt tctttcttcg
    17941 ttctcacacg catacatatc tccttggccc gtagccagcc atagaaggga aattcctgtt
    18001 tcaagagcgc attgaattac ccattcagca gggaaactat cccttaagta tctgttagcc
    18061 atagtgcttt ttgatacttc cagatgttcg cagagctgct gtcgtgagct gaaattgtaa
    18121 gccttaataa gcctgttaat cgcatcgcgc ccaccactat cattccctgc cttgattaaa
    18181 ctcataatca aacctcttga cgtatataaa aagtgatctt aatatccgct catggtttga
    18241 aaagtaaaat caaaccacat aaaacaagat aaaacgaacc caaactaaga gatactgcac
    18301 tatgagtact gatatttcaa ttcgtgtacc aaaagagatg gcaacgcctg ctgagttcgc
    18361 ggagtgggaa ggtatctccc gtggctcggt gtatcaaaaa attcaccatg gtcagcttgc
    18421 taagtacatg gtgaagaaag aaaaaaataa aggacgtgta agcctgcggt acctgatgta
    18481 caaaaccgac caggttcgtg agtctctggg tcattccaac ttccgcgtca ttgttggtca
    18541 gtaagttcga ttatgagaac tttctaaggg gcttgcatgt ttgattataa gatttccaaa
    18601 catccacact ttgacgaagc ctgccgggct ttcgcgctgc gtcacaacat ggcgaagctg
    18661 gcagaacgcg cgggaatgaa agtccagacg ctgcgtaaca agctgaaccc ggaacaaccg
    18721 catcagctca cgccgtcgga gatctggctg cttaccgata ttactgagga ctccacgctg
    18781 gtagatggtt tcctggcaca gattcactgc ctgccatgca taccgatgaa cgaagtggca
    18841 aaagagaagc tgccgcatta cgtcatgagc gctactgctg aaatcggacg tgttgctgcc
    18901 ggtgctgtat cgggtgatgt gaaaactact gcaggccgcc gcgatgttat cagtagcatc
    18961 aactcagtta ctcgtctaat ggcactggct gccgtttcca tgcaggcacg tttgcaggct
    19021 aacccggcga tggcaagcgc ggtggatacc gtgacgggcc tcggcgcttc attcggtctg
    19081 atctgaggtg gctatgctga ctaaagaacc atcttttgca tcacttctcg ttaagcaaag
    19141 tcctgcaatg cactgcggtc atggctggat tatggggaag gatggcaagc gctggcatcc
    19201 gtgccgctct caggatgcgt tgctggctga gctgtccgct aaaaagcagg ggaaaccatg
    19261 gctattgaag gtgatgctgc gactgttccg ctaagcgctg gcctccgtct taatgggtta
    19321 aaccacatcg cggaattaag ggcgaaagtg tttggcttaa atattgattc agaactggat
    19381 cgctttatta gcgatatgcg ggaccaacgg gatattaacc atgagcagaa taaacgcgca
    19441 ctagccgcaa tattctttat ggcaaagatt ccggcggaac gtcatagcgt caatgttagt
    19501 gaactgacga ctgacgaaaa gcgggagctg attaaagcaa tgaaccattt ccgtacagtg
    19561 gtgagtttat ttccaaatcg gctagccatg ccgaattaac caacaaccga aattaaaggc
    19621 gtaaacccgc cgggcttctt attgcccaaa ttcaggagaa acaacaatgc gaaatattga
    19681 aacccgaatc accaaaacag gaccagatga tgctggcctt aaccagatgc tgactgatgc
    19741 acgcatggaa gaacgccgtg gacgcgctga tgtgatggca gcacgtctgg actctttggc
    19801 tgcccgtatc gtgtcacgtc agcttaacca cacggaagcg gctgagctgc tgcgtcagga
    19861 agcggtgaag attcagaacg aagcgcagga gatccactga tggctgattc aatggacctc
    19921 gtacagcagc gcgttgaaga agaacgccag cgccacattc acaccgcccg caataaaacg
    19981 ccgggcgttt cccgtgttct ctgcattgat tgcgatgcac cgatcccgcc agcacgccgc
    20041 cgcgccattc cgggcgtgca gtgctgcgtc acctgtcagg aaatcgcaga gctgaaaggc
    20101 aaacactaca atggaggtgc tgtatgaata ccgataagat gacaattagc caacgtgcaa
    20161 atcaatggct tgataatgac tacttattta ttgataccga aacgaccggg ttgggtgatg
    20221 atgcggaaat agttgaaata tgcattattg atagtcatgg gtttattatg cttaatacgc
    20281 ttattaagcc cactaagcct atccctgatg aagcaatagc aattcatgga attactaatg
    20341 aaatggttgc ttttgcccct gcctggactg atatatgcgg ggcagtggag gaactatttc
    20401 ggcgctttgg gtttgttatc tataacgccg attttgatct ccggttaatt cgtcagacct
    20461 acgcattgaa tgaaagacct tctgaaggtg cgccatggat gcttgctgct cattctgttt
    20521 gcgcgatgaa gctttatgca gagtatcgag gcgagccggg acgatttaat ggctataaat
    20581 ggcataagct ggttgatgct gctgcgcatg aaggtgttgt agttgaaggt aaggcgcacc
    20641 gtgctttagc tgattgcaaa atgacgttag ggcttgtccg tgctctggct aaaggtggtg
    20701 ctaaatgagc accatcctga aatgggcggg aaataaaacc gccatcatgc cggaactgat
    20761 taagcatctg cctgcaggtc agcgactggt ggagccgttc gccggttcct gtgctgtgat
    20821 gatggcaaca gactatcctc attatcttgt cgcggatatt aatccagatc ttatcaatct
    20881 ctataaaaaa attgcccttg attgtgaagc tttcatatca cgcgcaaaga atatttttgc
    20941 gattgcgaat agagaagttg cttattacaa cattaggcat gaatttaatc attcctctga
    21001 aattactgat ttcatgaaag cagtatattt cctttatctc aatcgtcatg gttatcgtgg
    21061 actgtgccgc tataacctga gcggtcattt taatgtccct tacggtaatt ataaaaatcc
    21121 gtacttccct gaaaacgaaa tacgtgcttt tgcaaaaaag gcacaacgcg caacgtttat
    21181 ctgcgccagc tatgatgaga cgctggcaat gctgcgggcg ggggatgtgg tttattgtga
    21241 tccgccatat gacggcacat ttagcggtta tcacactgcc agttttaccg gggacgatca
    21301 gtaccatctg gcgtctattc ttgaacgccg gtcatcagaa ggtcatccga ttattgtgtc
    21361 caacagcgac acctctctga cacgttcctt atatcgtaat ttcacccgcc accgcatcat
    21421 cgcaaagcgc agcatgggtg tggctgcagg tgatggtaaa tctgcaacag aaatcatcgc
    21481 tacgaagtta gtgcgctggt tcggtgttga tttggcgtct ggtcctgatg tctcggtgga
    21541 aactgaggtg cgggcgtggc agtgagtaaa atcacattac attatgcaca aaccaccggc
    21601 ggctcgaatg aggccgccgc agcctttcca tggaataccc caaaaaaagc ggttaacccg
    21661 tatctggacc cggcggaatt tgcgccggag tctgcgcttt caaacctgat cgctctttac
    21721 gctgtggata acgagcagga gcagttgcgc cgtgagacgc tgagcgatga ggtctgggag
    21781 cgctatttct tcaatgaatc ccgtgatcct gtccagcgtg aaatggagca ggatcggctg
    21841 attaaccatg ccaaaacggc gcgcgagcag cagcgtttta atcccgatct ggtcattatt
    21901 gccaacgtgg gcgcccaacc ggcgcatatc agcaagcctc tgctggagcg gattaaatat
    21961 ttccatagtc tgggcagagc aaaagcttat tcccgctacc tgcaaaaaac aatcaggccg
    22021 tgtcttgagc ggctggagcg cgtgcgcgac agtcaggtat ctgcctcttt ccggttcatg
    22081 gcgagtcatg acgggctgga ggggctgctg gtactccctg aaatgaatca ggatcaggtt
    22141 aaacgcctat ccacgctggt tgcggcacat atgagcatgt gtcttgatgc agcctgcggt
    22201 gatctgtttg tcagtgatga tgttaaacca gaagaaattc gtcaggcatg ggaaagggtt
    22261 gctgcagagg ccatgcgcct tgaggtcatc ccgcctgcgt ttgagcagtt gcgccgcaaa
    22321 aagcgccgcc gtaagccggt gccttatgaa ctgatcccac cgtcgctggc ccgtatgctg
    22381 tgcgcggact ggtggtatcg caaattgtgg cagatgcgct gcgagtggcg ggaggagcag
    22441 ttgcgcgccg tctgcctggt caacaagaaa gcctcaccgt atgtcagcta cgaagccgtg
    22501 atccacaaac gcgagcagcg ccgcaaatcg ctggagttct tccgctcgca tgagctgatc
    22561 aacgaagacg gcgacacgct ggacatggaa gacgtggtga acgccagcaa cagcaacccg
    22621 gcgcaccgcc gtaatgaaat gatggcctgt gttaaggggc tggagctgat cgcggaaatg
    22681 cgcggagact gcgcggtgtt ttataccatc acctgcccgt cacgcttcca cgcaaccctc
    22741 aacaacggca ggcctaatcc gaagtggacc agtgccactg tccggcagag cagtgactat
    22801 ctggttgata cgttcgccgc tttccgcaag gcaatgcaca aggccgggct gcgctggtat
    22861 ggcgtccgcg ttgcagagcc gcaccatgac ggcaccgtgc actggcatct tctgtgcttc
    22921 atgcgcaaaa aagaccgccg ttccatcacc gcgctgttgc gtaagtttgc catccgtgaa
    22981 gaccgcgagg agctgggcgc caataccggg ccgcgcttca agcccgagct aatcaacccg
    23041 cgcaagggta cgccgacaag ctacatcgcc aaatacatca gcaagaacat cgacgggcgc
    23101 gggctggcta aagaaatcag caaagaaacc ggcagatcac tgcgtgacag cgccgagcat
    23161 gtcagcgcct gggcgtcact gcatcgtgtc cagcagttcc gtttctttgg tattccgggg
    23221 cgtcaggcat accgcgagct gcgcttgctg gctggtcagg cggcgagagt gcagggcgaa
    23281 cgcaaagcgg gtgcgccggt actggataat ccgcgtctgg atgcggtact ggcggcggct
    23341 gatgcgggct gctttgccac ctatatcatg aagcagggcg gtgtgctggt tccccgcaaa
    23401 catcaccttg tccgcacggc atatgagctt aacgatgagc cgagcgccta cggcgatcac
    23461 ggtatccgta tatatggcat ctggtccccg attgcggagg gcaagatttg cacgcacgcg
    23521 gtgaagtgga aaaaggttcg taaagccgtt gacgttcagg aggcggcagc cgaccagggc
    23581 gcttgcgccc cttggactcg gactcgtggc aataactgtc cccctgttga aaatctgaac
    23641 aaatcagggg gtgatttacc cgatattaaa accatgaatg agaaggaact gcaggattat
    23701 ctccacaata tgggccagaa ggaacggcgg gaacttacag ccaggttgag actggtaaaa
    23761 ccgaagcgga aaacagtata caaacagaat atttcggagc agcaacgcct gcagcttgag
    23821 gcagaactga cagccagagg gtttgaaggt agtgcatctg agattgattt gcttctgcgt
    23881 ggtggcagca ttccgtcagg tgccgggcta cggatttttt accgcaacca tcgactgcag
    23941 gaagatgaca aatggcgtca gtgatactga cggcaaggct ttaacaattc atgctcttaa
    24001 cgaccttcgt aagaacgttc tcattgacgg ataaaaaata ttttac
//
LOCUS       DAJVKX010000061        23975 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000061 DAJVKX010000000
VERSION     DAJVKX010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23975
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.061"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..511)
                     /gene="mobB"
                     /locus_tag="OPY25_002527"
     CDS             complement(<1..511)
                     /gene="mobB"
                     /locus_tag="OPY25_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HCS0928120.1"
                     /translation="MIPLLAIAAWSGTGKTTLLKKLIPALCAHGIRPGLIKHTHHDMD
                     VDKPGKDSYELRKAGAAQTLVASQQRWALMTETPGQEELDLAWLVSRMDASKLDLVLV
                     EGFKHEAVAKILLFRQGCGHSEEELILDEHVIAVASDIPLAVAVPVLDLNDVSQISAF
                     ILRWLEKARS"
     gene            complement(508..1092)
                     /gene="mobA"
                     /locus_tag="OPY25_002528"
     CDS             complement(508..1092)
                     /gene="mobA"
                     /locus_tag="OPY25_002528"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HCS0928121.1"
                     /translation="MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALA
                     PQLATVVISANRHLDIYQASGLKVIPDSIADFPGPLAGMLSVFQQVAGDWFLFCPCDN
                     PCIPHNLVDRLAAHRHGAPVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIF
                     MRQVGGHAVDFSDCKEAFVNVNTPEELAQWQKRP"
     gene            1162..1431
                     /locus_tag="OPY25_002529"
     CDS             1162..1431
                     /locus_tag="OPY25_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HCS0928122.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLTQFLQKLAKESGFDGKLED
                     LTDDILIYHLKMRDSAKDAAIPGIQKDYEEDFKTALLRARGVIKE"
     gene            1508..2494
                     /locus_tag="OPY25_002530"
     CDS             1508..2494
                     /locus_tag="OPY25_002530"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HCS0928123.1"
                     /translation="MNDNAFTFQTLHPETIMDALFEQGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWSVDQIREEHQFALELVKDEVPVAAPLAFNGQTLLAHQGYH
                     YAIFPSVGGRQFEADNIDQMEAVGRYLGRLHQTGRKRPFTFRPDIGLAEYLFEPRQVF
                     EDAALIPSGQKAAFLKATDTLLSAVTECWRTDFATLRLHGDCHAGNILWRDGPLFVDL
                     DDARNGPAIQDLWMLLNGNKAEQRMQLETIIEAYEEVSEFDTAEIGLIEPLRAMRLVY
                     YLAWLIRRWGDPAFPKNFPWLTGEDYWQRQTTTFIEQTKILHEPPLQLTPMY"
     gene            2511..3134
                     /gene="dsbA"
                     /locus_tag="OPY25_002531"
     CDS             2511..3134
                     /gene="dsbA"
                     /locus_tag="OPY25_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HCS0928124.1"
                     /translation="MKKIWLALAGMVLAFSASAAQISDGKQYITLDKPVAGEPQVLEF
                     FSFYCPHCYQFEEVLHVSDNVKKKLPKGTKMTKYHVEFLGPLGKELTQAWAVAMALGV
                     EDKVTVPLFEAVQKTQTVQSAADIRKVFVDAGVKGEDYDAAWNSFVVKSLVAQQEKAA
                     ADLQLQGVPAMFVNGKYQINPQGMDTSSMDVFVQQYADTVKYLVDKK"
     gene            complement(3147..4055)
                     /locus_tag="OPY25_002532"
     CDS             complement(3147..4055)
                     /locus_tag="OPY25_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HCS0928125.1"
                     /translation="MTRILAAITLPLSIVLTILVTIVCSVPIIVAGMVKLLLPVPGIW
                     RKVSIFCNFMMYCWCAGLAALLRLNPHLQWDVEGLEGLSKKNWYLLICNHRSWADIVV
                     LCVLFRKHIPMNKYFLKQQLAWVPFIGLACWALDMPFMKRYSRSYLLRHPDRRGKDVE
                     TTRRSCEKFRRYPTTIVNFVEGSRFTHEKRQQTHSPYQHLLPPKAAGIAMAINVLGSQ
                     FDKLLNITLCYPNNDRHPFYDMLSGRLTRIVVRVQLEPINEELHGDYVNDKTFKRRFQ
                     RWLNTLWDKKDIQIEEIKTSYKNAGQ"
     gene            4443..7229
                     /gene="polA"
                     /locus_tag="OPY25_002533"
     CDS             4443..7229
                     /gene="polA"
                     /locus_tag="OPY25_002533"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCS0928126.1"
                     /translation="MVQIPENPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYQPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAIVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKVGRPVLISTGDKDMAQLVTQNITLINTMTNTIL
                     GPDEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLTFRGAKTMAGKLAQNKDVAYLSYKLATIKTDVELELTCEQLEVQQPIADELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETVVIDESPSEPAAALSYENYVTIL
                     DDVTLESWIEKLKKAPVFAFDTETDSLDNIAANLVGLSFAIEPGVAAYVPVAHDYLDA
                     PDQISRQRALELLKPLLEDEKVRKVGQNLKYDRGVLQNYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLSDRWLKHKTITFEDIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPELQQHKGPLNVFENIEMPLVPVLSRVERNGVKIDPAVLHKHSEEITLRLAEL
                     EKKAHDIAGEAFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYLIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLDSVTGEQRRSAKAINFGLIYGMSAFGLSRQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLEGRRLYLPDIKSSNAARRAGAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDLDAVAKRIHQLMENCTRIDVPL
                     LVEVGSGENWDQAH"
     gene            complement(7566..8198)
                     /locus_tag="OPY25_002534"
     CDS             complement(7566..8198)
                     /locus_tag="OPY25_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCS0928127.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDCGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVVDGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIQWAVESNIQVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVEAFSSLKKQGVDKLRQKLDSWFSELAPVEEIQDGE"
     gene            8438..8662
                     /locus_tag="OPY25_002535"
     CDS             8438..8662
                     /locus_tag="OPY25_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928128.1"
                     /translation="MSLPQKSKVMHIARTLTGSTTQDEGQERQEAKTQDCQEDKRPET
                     LVKGNGNNMECSRLREKQGVLIANRDGGTR"
     gene            8781..9296
                     /gene="yihI"
                     /locus_tag="OPY25_002536"
     CDS             8781..9296
                     /gene="yihI"
                     /locus_tag="OPY25_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HCS0928129.1"
                     /translation="MKKPTSAPRSKAFGKQRRKTREELNQEARDRKRLKKHRGHAPGS
                     RAAGGNSASGGGNQNQQKDPRIGSKTPVPLGVTEKVTQQHKPKSEKPMLSPQAELDLL
                     ETDERLDALLERLEAGETLSAEDQAWVDAKLDRIDELMQKLGLSYDDDEEDDEEDEKQ
                     EDMMRLLRGGN"
     gene            9485..10858
                     /gene="hemN"
                     /locus_tag="OPY25_002537"
     CDS             9485..10858
                     /gene="hemN"
                     /locus_tag="OPY25_002537"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCS0928130.1"
                     /translation="MSEQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFEDAAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIRHRAPLFAD
                     RHVSQLHWGGGTPTYLNKAQISRLMTLLRENFHFNTDAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHARDIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVTELNPDRLSVFNYAHLPTLFAAQRKIKDADLPSAQQKLDILQETIVS
                     LTQAGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     GYMQNQKELKRYYQQVDERGNALWRGITLTRDDCIRRDVIKALICNFRLDFNAVEQQW
                     GLHFAEYFAEDLQLLSPLAKDGLVDISEKGIQVTAKGRLLIRNICMCFDAYLRQKARM
                     QQFSRVI"
     gene            complement(10948..11058)
                     /locus_tag="OPY25_002538"
     CDS             complement(10948..11058)
                     /locus_tag="OPY25_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HCS0928131.1"
                     /translation="MLESIINLVSSGAVDSHTPQTALAAVLCAALVGLFS"
     gene            complement(11171..12580)
                     /gene="glnG"
                     /locus_tag="OPY25_002539"
     CDS             complement(11171..12580)
                     /gene="glnG"
                     /locus_tag="OPY25_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HCS0928132.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCITFENGNEVLAALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNIEVNGPTTDMIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLERRVQEGKFREDLFHRLNVIRIHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETETALTRLAWPGNVRQLENTCRWLTVMAAGQEVLTQDLPGELFEASAPD
                     SPSHLPPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAK
                     LLGWGRNTLTRKLKELGME"
     gene            complement(12589..13638)
                     /gene="glnL"
                     /locus_tag="OPY25_002540"
     CDS             complement(12589..13638)
                     /gene="glnL"
                     /locus_tag="OPY25_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HCS0928133.1"
                     /translation="MASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIDLMRESLAAGQGFTDNEVTLVIDSRSHILSLTAQRLPDD
                     FILLEMAPMDNQRRLSQEQLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNV
                     RLIRDYDPSLPELPHDPEQIEQVLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHAGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            complement(13913..15322)
                     /gene="glnA"
                     /locus_tag="OPY25_002541"
     CDS             complement(13913..15322)
                     /gene="glnA"
                     /locus_tag="OPY25_002541"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HCS0928134.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWN
                     SSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLA
                     KNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            15699..17522
                     /gene="typA"
                     /locus_tag="OPY25_002542"
     CDS             15699..17522
                     /gene="typA"
                     /locus_tag="OPY25_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HCS0928135.1"
                     /translation="MIENLRNIAIIAHVDHGKTTLVDKLLQQSGTFDARAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAHGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIIYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPLQMQISQLDYNNYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLTHLGLERIDSDIAEAGDIIAI
                     TGLGELNISDTICDPQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDIRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVILVPPIKMSLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRGQKEE"
     gene            complement(17577..18311)
                     /locus_tag="OPY25_002543"
     CDS             complement(17577..18311)
                     /locus_tag="OPY25_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCS0928136.1"
                     /translation="MRYRLIAFDLDGTLLNRNKQILPESLTAIRQMQDMGCRIMLVTG
                     RSHREAYAYYQTLALTEPMICCNGSYIYQPAQQQILDPLPLTHLQTEKILARVYPLKP
                     TIRADDKIIFQADELSSRENIWQISVVHRHIKQLQNIAEFIQHELQLSCTWSWHHQLD
                     ILQKGCSKGQSLARYAQQQHIAMREVMAFGDNDNDAEMLRLAGLGVAMGNASARAKVY
                     ADSVIGRHNTPTIADFLTTLSLSQRE"
     gene            complement(18296..19174)
                     /locus_tag="OPY25_002544"
     CDS             complement(18296..19174)
                     /locus_tag="OPY25_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4011 family radical SAM protein"
                     /protein_id="HCS0928137.1"
                     /translation="MSIPALRDIHTLFYRGYLKSCNYHCGYCPFHKHARNDKKRDEAA
                     LWRMVDHLPLLGTPLNVMITPYGEALRLRYYMAALADISRYPHVQAVGIQTNASFSLM
                     SLLESFRAGGGDISKLRLWCSFHPSQITAERFLQQCLALSAAGITWCAGAVASMKDID
                     QFRWLRQRLPDQNYFWFNANECANTRHTVEETIAFSELDPLYVVETQQWPAQLDICTA
                     GRKSIFMNAEGDLFACHISKIKMGNLYQQRLNSPACQAKQCHCFLAYQHRLDIPLLNH
                     LDASRCFRIGRSCDIV"
     gene            complement(19171..20412)
                     /locus_tag="OPY25_002545"
                     /pseudo
     CDS             complement(19171..20412)
                     /locus_tag="OPY25_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462892.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="STM4012 family radical SAM protein"
     gene            complement(20414..21289)
                     /locus_tag="OPY25_002546"
     CDS             complement(20414..21289)
                     /locus_tag="OPY25_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462893.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4013/SEN3800 family hydrolase"
                     /protein_id="HCS0928138.1"
                     /translation="MYNSMDEVPVSLHASIDTGDGEFDMNALISNNAHILFIVLDSLR
                     YDIALQEQTAGNTPNLNHYGQWTKCEAAGNFTWPSHHAMFSGFMPKPIDDTVNQTMLL
                     FPKDIGLGRKGPKNAFAFDDATWIKSLENKGYQTICIGGVSFFNNRSGMGKVFPSMFK
                     ESYWHPRFACTVKESMDNQIHYIQKIMAERAGSQPVMMYINIDTIHYPNHFYVEGAAP
                     GDTVEAHAAALRYIDARIDGLLNIFRQTGGETFVIVCSDHGTCYGEDGKYFHSFNHPI
                     VNTVPYMHFLLSGNH"
     gene            complement(21282..22307)
                     /locus_tag="OPY25_002547"
                     /pseudo
     CDS             complement(21282..22307)
                     /locus_tag="OPY25_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462894.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="STM4014 family protein"
     gene            complement(22320..23168)
                     /locus_tag="OPY25_002548"
     CDS             complement(22320..23168)
                     /locus_tag="OPY25_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4015 family protein"
                     /protein_id="HCS0928139.1"
                     /translation="MNKRFNIDWDNELTQEQLINLILTDEDLPKLRSLTIGNWGDCWE
                     DETCQPIIDMIVENAPRFSHLESLFIGDMESEDCEISWIKQGDYSRLYAALPNLKELI
                     IKGASDLRLGAIHHEKLEHLEIISGGIPSNVLAELQNAQLPALKTLKLFLGVEEYGFD
                     GSLDNVMALVSKDLFPQLNHLGLMNSEEQDDIARRVLESNILPQLNVLELSCGTLTDS
                     GAEALLEHKDRIAHLETLDLHHHYLTPEMQEKLKAALPIPLNLSEALEPDDYDGDIYM
                     NAMYTE"
     gene            complement(23325..>23975)
                     /gene="ompL"
                     /locus_tag="OPY25_002549"
     CDS             complement(23325..>23975)
                     /gene="ompL"
                     /locus_tag="OPY25_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HCS0928140.1"
                     /translation="STSVFAGAYVENREAYNLASDQMEFMLRVGYNSDMGAGIMLTNT
                     YTLQRDDELKHGYNEIEGWYPLFKPTDKLTIQPGGLINDKSIGSGGAVYLDINYKFTP
                     WFNLTVRNRYNHNNYSSTDLNGELDNNDSYEIGNYWNFIITDKFSYTFEPHYFYNVND
                     FNSSNGTKHHWEITNTFRYRINEHWLPYFELRWLDRNVGLYHREQNQIRIGAKYFF"
BASE COUNT         5998 a         5939 c         6238 g         5800 t
ORIGIN      
        1 aggaacgtgc tttctctaac caccgcaaaa tgaaggcaga aatctgcgat acatcattaa
       61 gatccaaaac gggtaccgct acggcaagtg gaatatcact ggcaaccgca ataacatgct
      121 catcaagaat taattcttcc tcgctgtgcc cacatccctg acgaaaaagt aagatcttcg
      181 caactgcttc gtgtttaaac ccttcaacaa gcaccagatc cagttttgat gcatccatcc
      241 ggctcaccag ccatgccaga tccaactctt cttgccccgg cgtttccgtc attaacgccc
      301 agcgctgctg actggcaacc agcgtctgtg ccgccccggc tttacgcagc tcgtagctat
      361 ctttacccgg tttatcgaca tccatatcat gatgggtatg cttaatcagc cctggccgaa
      421 taccgtgcgc acaaagtgct gggatcagtt ttttcagcag tgttgttttt cccgtgccgc
      481 tccatgcggc aatggcgagt agcggtatca tggtctcttt tgccattgcg cgagttcctc
      541 cggcgtgttg acgttcacaa atgcctcctt acaatcgctg aaatcaacgg cgtgtccgcc
      601 tacctggcgc ataaaaatca ttacccgccg ctcgcctgct tgcaaataag ctgtcaactg
      661 gggctcaacg gcacgattaa tcaacgcgat cgttggatga tcgcgttctc catcatgaac
      721 ccaaaccacg ggtgcgccat gacgatgcgc tgctaaacga tcgaccaggt tgtgggggat
      781 acaaggattg tcacagggac aaaacagaaa ccagtcgcct gctacctgct gaaaaacgga
      841 aagcataccc gccagcggac cgggaaagtc agcgattgaa tccggaatga ctttcaggcc
      901 gctggcctgg tagatatcca gatggcgatt agcactaatt acgaccgtag caagttgtgg
      961 cgcgagcgcg tcggcaacgt gtcgccagag cggtttcccg tccagttcaa gcagaccttt
     1021 atccgcacct cccatccgcc gggctttacc gcctgccagt accacgccgg ttattacttc
     1081 atccagattc accgatatcg cctcttttat tgtgggattg accctgctac cgtgtctgta
     1141 tcaagaataa ggagcacagc tatgaaatgt aaacgcctga atgaagtcat tgaactcctc
     1201 cagccagcct ggcagaaaga gcctgatctt aatctgacgc aatttttgca gaaactggcg
     1261 aaagagtcag gttttgacgg caaactggaa gatttaactg atgatatcct gatctaccat
     1321 ctgaaaatgc gcgattccgc caaagacgcc gccattccag ggattcaaaa agactatgaa
     1381 gaggacttta aaacggcgct tttacgcgcc cgcggcgtta ttaaagagta aaaccttgta
     1441 agcggcacca ccgaaatcgc cacgaaatga tatcctgaat cattcgtagt attttccgga
     1501 tgatgggatg aacgacaacg cttttacttt ccagacgcta cacccggaaa ccatcatgga
     1561 tgcgctgttt gaacagggga tcagggtgga ttccgggctg actccactaa acagttatga
     1621 aaaccgcgtc tatcagtttc aggatgaaga ccgtcgacgt tttgtcgtta agttttatcg
     1681 tcctgaacgc tggtctgttg atcaaattcg ggaagaacac caattcgcgc ttgaactggt
     1741 gaaggatgag gttccggttg ctgctccgct cgcgtttaat ggccagacgc tgttagcgca
     1801 tcagggctat cattatgcca ttttccccag cgtaggcggt cgtcagtttg aagcagacaa
     1861 tatcgatcag atggaggcgg tagggcgtta tcttggccga ttgcatcaga cggggcgaaa
     1921 acgtcctttc actttccggc ctgacattgg gcttgcagag tatctttttg aacctcgcca
     1981 ggtattcgaa gatgccgcac tgattccctc cgggcaaaaa gcggctttcc tgaaagccac
     2041 tgatactcta ctgtctgcgg ttaccgaatg ctggcgcacc gatttcgcca cgctgcgatt
     2101 gcacggcgat tgtcatgccg gcaacattct atggcgtgat ggaccgctgt ttgtcgattt
     2161 agatgatgcc cgtaacggcc cggcgataca ggatttatgg atgctgctga acggcaacaa
     2221 agccgaacag cgaatgcagc ttgaaaccat tattgaagct tatgaagaag ttagtgagtt
     2281 cgatacggct gaaattggtc tcattgaacc tttacgcgcc atgcgtttag tttattatct
     2341 tgcctggttg attcgtcgtt ggggcgatcc tgcgtttcca aaaaactttc cctggttaac
     2401 aggggaagat tactggcagc gacagacaac gacttttatt gagcagacta aaattttgca
     2461 cgaaccccct ttacaattaa cgccaatgta ttaatcggag agagttgatc atgaaaaaga
     2521 tttggctggc gctggctggt atggttttag cttttagcgc ctcggcagca cagatcagcg
     2581 acggtaaaca gtatatcacg ctggataaac cggtcgctgg cgaaccccag gtactggagt
     2641 ttttctcatt ctactgccca cattgttatc agtttgaaga agtgcttcat gtgtctgaca
     2701 atgtgaagaa aaagctgccg aaaggcacca agatgaccaa gtaccacgtt gagttcctgg
     2761 ggccgttggg caaggagctc acccaggcat gggcggtggc gatggcgttg ggggtagaag
     2821 ataaagtcac ggtcccgctg tttgaagccg tacagaaaac ccagacagta caatctgccg
     2881 cggatatccg taaagtgttc gttgatgcgg gcgtaaaagg cgaagattac gatgcggcat
     2941 ggaacagctt cgtggtgaaa tcactggttg cgcaacagga gaaagccgcg gctgacctgc
     3001 aactgcaggg cgttccggcg atgttcgtca atggcaaata ccagattaac ccacaaggca
     3061 tggataccag cagcatggat gtttttgttc agcagtatgc tgataccgtg aaatatttgg
     3121 ttgataaaaa ataaaaagaa cgccggtcac tgaccggcgt ttttataaga tgttttaatc
     3181 tcttctatct gtatatcttt cttatcccac agcgtattaa gccaacgttg aaaacggcgt
     3241 ttgaatgttt tgtcgttcac gtaatcgccg tgcagttctt catttatggg ttccagttgc
     3301 acccgaacaa caatacgcgt cagcctaccg cttagcatat cgtagaaggg gtggcgatcg
     3361 ttgtttgggt aacacaacgt aatattaagc agcttatcga actgtgagcc taaaacatta
     3421 atcgccattg caataccggc tgcttttggt ggcaacagat gttgataggg tgaatgcgtt
     3481 tgctgacgtt tctcatgcgt aaatcgcgag ccttcaacaa agttaacgat agtggtggga
     3541 taccgacgaa acttctcgca agagcggcga gttgtttcaa catctttgcc acgtcgatcg
     3601 gggtggcgga gcagatagct acgagagtag cgcttcataa acggcatatc taatgcccag
     3661 cacgccaggc cgatgaacgg cacccaggcc aattgctgtt taagaaagta cttattcatt
     3721 gggatatgct tgcggaacag aacgcaaagc acaacgatat cggcccagct gcggtgatta
     3781 caaatcagta aataccaatt tttcttgctc agcccttcta acccttctac atcccattgc
     3841 aagtgcggat taaggcgtaa cagcgctgca agaccagcac accagcaata catcatgaaa
     3901 ttgcagaaaa tggagacctt gcgccagata ccgggaacag gcaaaaggag ctttaccatg
     3961 ccggcaacga tgatcggtac tgagcaaaca atagtgacca ggatggttaa tacgatactc
     4021 aatgggagcg tgatagccgc gagtattctc gtcataataa attattcaaa agttagccat
     4081 aaacggtgtg cgaaaagggc gcaagaggct gattctatca gaaaacgatg ctaatgatgg
     4141 cgctgagtga aatagaaaca ctcgtaacaa ctatccacat tatgataacg gcatgaatca
     4201 gataatcaga aaatcgtgat gttaacaact cattgaaaat aatgggtaat tattaagagg
     4261 agaaggctat cgcgctgatt ttaaagtaat ggtaagaatt tacacacaaa gttatccaca
     4321 ggttgttttg cgagcgatcc tgaagatcga caaaactttt ccgcaaatgc ggcgaaaaac
     4381 tcaagttttc ctcctgtatg tggcatcctt taaccataat ctgttaaaca ggcacggaca
     4441 ttatggttca gatcccagaa aacccactta ttctcgtaga tggctcatcc tatctctatc
     4501 gcgcctatca tgcgtttccg ccgttaacca acagcgcggg agaacctacg ggcgcaatgt
     4561 atggtgtcct caacatgttg cgcagcctga tcatgcagta tcagccgacg catgctgcgg
     4621 tggtgtttga cgccaaagga aaaaccttcc gtgacgagct ctttgaacac tacaaatcgc
     4681 atcgtcctcc gatgccggat gatctgcgtg cgcaaataga gccgttacat gccatagtta
     4741 aagccatggg gttacctctg ctggcggtct ctggcgtaga agcggatgac gttatcggta
     4801 cactggcgcg agaagcggag aaggtggggc gtccggtatt aatcagcacc ggcgataaag
     4861 atatggcaca gttggtgacg cagaatatta cgctgatcaa caccatgact aacaccatcc
     4921 tcggcccgga tgaagtcgtt aataagtacg gtgtgccgcc tgagctgatt attgactttc
     4981 tggcgctgat gggggactcc tcggataata ttccgggcgt accaggcgtg ggtgagaaga
     5041 cggcgcaagc cttgcttcag ggattgggcg gcctggatac gctgtacgcc gagccggaaa
     5101 aaattgccgg tctcactttc cgcggcgcca aaacgatggc cggtaaatta gcgcagaata
     5161 aagacgtagc gtacctgtct tataagctcg ccaccattaa aacggatgtt gagctggagc
     5221 tgacctgcga acagcttgaa gtgcagcagc cgattgcgga tgaactgctg ggcctgttta
     5281 aaaaatatga gttcaagcgc tggacggcgg acgtcgaggc aggcaagtgg ctacaggcaa
     5341 agggcgcgaa accggcggcc aaaccgcagg aaacggtcgt tattgatgaa tcgcccagcg
     5401 aaccggcagc ggcgctctct tatgaaaatt atgtcacgat tctggatgac gttacgctgg
     5461 aaagctggat tgaaaagctg aaaaaagcgc cagtttttgc tttcgacacg gagaccgaca
     5521 gcctggataa tatcgccgcc aacctggtgg gcctctcgtt tgccatcgaa cctggcgttg
     5581 ccgcgtatgt acctgtcgcg catgattatc tggacgctcc ggatcaaatc tcccgccagc
     5641 gtgctctgga actgctgaag cctctgctgg aagatgaaaa agtgcgcaaa gtggggcaaa
     5701 acctcaagta cgatcgcggc gtcttgcaaa attacggtat tgagctgcgc ggtatcgcct
     5761 tcgataccat gcttgagtct tacattctga acagcgtcgc cggacgccat gatatggaca
     5821 gcttgtccga tcgttggctg aagcacaaaa ctatcacctt tgaagacatt gccggtaaag
     5881 gtaaaaacca gctcaccttt aaccagatcg cactggagga agcggggcgc tatgcggcag
     5941 aagatgcgga tgtcacgtta cagttgcatc tcaaaatgtg gcctgagctc cagcagcaca
     6001 aaggcccgct gaatgttttc gaaaacatcg aaatgccgct ggtgccggta ctgtcacgcg
     6061 ttgagcgcaa tggcgtaaaa atcgatcctg ccgtcctgca caaacattcg gaagaaatca
     6121 cgctacgtct ggcggaactg gaaaagaaag cgcatgacat tgcgggcgag gcgttcaacc
     6181 tgtcctcgac gaagcagttg cagaccatcc tgtttgaaaa gcagggtatt aagccgttga
     6241 agaaaacgcc tggcggcgcg ccgtcaacgt cggaagaggt gctggaagag ctggcgctgg
     6301 actatccgct gccgaaagtg attctggagt atcgtggtct ggcgaagcta aaatccacct
     6361 ataccgataa gctgccgctg atgattaacc cgaaaaccgg gcgcgtccat acgtcctatc
     6421 atcaggcggt aacggcgacg ggacgtttat cgtccaccga tccgaacctg caaaatattc
     6481 cggtgcgcaa tgaagaaggc cgccgcattc gtcaggcatt tattgcgcct gaggattatc
     6541 tcatcgtatc tgcggactat tcacagattg agctgcgtat tatggcgcat ctttcccgtg
     6601 ataaagggct gctcacggcg ttcgccgaag ggaaagatat tcaccgcgca acggcggcgg
     6661 aagtctttgg cttgccgctg gatagcgtga ccggggaaca gcgccgaagt gcgaaagcca
     6721 ttaactttgg cctgatttac gggatgagcg ccttcggtct ttctcgccag cttaatattc
     6781 cgcgtaaaga ggcgcagaag tatatggatc tctacttcga acgctaccct ggcgtgctgg
     6841 aatatatgga gcgcacccgc gctcaggcaa aagaacaagg ctatgtggaa actctggagg
     6901 ggcgccgcct ttacctgccg gatattaaat ccagcaacgc ggcgcggcgc gcgggggcgg
     6961 aacgcgcggc gatcaatgct cccatgcaag gaacggctgc cgatatcatc aagcgcgcca
     7021 tgattgccgt cgatgcctgg ctacaggccg agcagccacg cgtgcggatg attatgcagg
     7081 tacacgatga attagtgttc gaggtgcata aagacgactt agatgcggta gcaaaacgta
     7141 tccatcagtt gatggaaaac tgcacgcgta ttgatgtgcc gttgctggtg gaagtcggta
     7201 gcggagaaaa ttgggatcaa gcgcactaag catttaagga ataacgcgct tttttcgtaa
     7261 ttaagcaaca taagcacggg ggttttgtga tgggtattag aattccctat gtaaagaatg
     7321 aaaaaaaaaa ttacgaaaag gtctttctgt gttgctcaaa aaagagtaaa gttattcacg
     7381 tagggtacag aggtaagatg ttctatcttt cagacctttt acttcacgta atcggatttg
     7441 gctgaatatt ttagccgccc cagtcagttt atgactgggg cgttttttat tgggcgtaag
     7501 aaaagtttcg ctcgcaccgt aggccggata agacgcgcag cggcgccatc cggcatagcg
     7561 ggtgattatt ccccgtcctg aatctcttcg accggtgcca gttcactaaa ccagctatcc
     7621 agtttctgac gtaacttatc cactccctgc tttttcagcg aggaaaacgc ttctacctgc
     7681 acatcgccat taaaagccag cacggcttca cgtaccatat tcaactgcgc cttgcgcgcg
     7741 ccgctggcca gtttgtccgc tttggtcagc agaaccagaa cctggatatt gctctctaca
     7801 gcccactgga tcatctgttg gtcgaggtct ttcaacggat ggcggatatc cattaaaacg
     7861 actaagccct gtaggctttg acgtttctcc agatattccc ccagcgcgcg ttgccacttg
     7921 cgtttcatct cttccgggac ttccgcgtag ccatagcccg gcaggtcgac caaccgtttg
     7981 ccatctacga cttcaaacag gttaatcaat tgggtacggc ccggcgtttt agaggtgcgc
     8041 gccaggcttt tttggttggt caacgtgttc agggcgctgg atttgcctgc attggaacgg
     8101 ccagcaaaag ccacttcaat tccgcaatcg gaaggtaaat ggcgaatatc aggcgcactc
     8161 atcacaaaat gcgtctgttg ataattcagg ttagtcaaag cggtcgtctc cgtcagtcaa
     8221 agcattgtgg cgattatacc tgaacgccag caaaagacgg atttttcggc gcgtcggtgc
     8281 tgtaagcaaa agccatacgc tttgtgagac attgtccatt gcacttatgc gacatgacag
     8341 agtcgttgtc aggctaaaag ccagttaata tagttaaatc atgaatttat agaaaggtaa
     8401 ttgtctgaaa aaaagggatt tgccgtgtcg gtatcttgtg agtttacccc aaaagagtaa
     8461 agtaatgcac atagcgagga cgctaacagg atcaacgact caggatgagg gtcaggagcg
     8521 ccaggaggcg aagacacagg attgtcagga agacaaacgt ccggagacgt tagtaaaagg
     8581 aaatggaaac aacatggaat gttccaggct aagggaaaaa cagggcgtgt tgatagccaa
     8641 cagggatggt ggaacccgtt aagggtcgtg agtcaagaaa aaaggcggca gattactctg
     8701 tcgccttttt tctttgcttg ctttctgcta gattccgcct caattctata ctgaataaaa
     8761 cggcttaaag atctgacatc atgaaaaaac caacctctgc accgcgcagt aaagcctttg
     8821 gcaaacagcg tcgtaaaacg cgtgaagagt taaaccagga ggcgcgcgac cgtaaacgcc
     8881 tgaaaaaaca tcgcggccat gcgccgggaa gtcgcgcggc gggcggcaat tccgcttcgg
     8941 gcggcggcaa tcagaatcaa caaaaagatc cacgtattgg cagtaaaaca cctgttccat
     9001 tgggcgtgac tgaaaaagtg acccaacagc ataaaccgaa aagtgagaaa cctatgcttt
     9061 caccgcaggc ggagttggat ttactggaaa cggatgagcg cctggatgcg ctgttagaac
     9121 gtctggaagc gggcgaaacc ctgagtgcgg aagatcaagc ctgggtagat gccaaactgg
     9181 atcgtattga tgaactgatg cagaagcttg gtctgtctta cgatgacgac gaagaagacg
     9241 acgaagagga cgagaagcag gaagatatga tgcgcctgct aagaggcggc aactaacggg
     9301 tttacaccgt gggcttgccc gtcctgctta taacccttcc ggttatatgt tatctggtgt
     9361 ggttattcgt taaactacag cgattgtcgc ggcgacagaa atggctgcgc agccggcttg
     9421 ccgcccgtca tggcgtgaag ccggtacgcc gtacccgcca gagacgccat cggaaggagt
     9481 gagcatgtct gaacagcaaa tagactggga tctggccctg atccagaaat ataactattc
     9541 cgggccacga tatacctcgt acccaaccgc gctggagttt tctgaagact tcgaggacgc
     9601 cgcattcttg caggctgtgg cgcgttatcc tgaacgtccg ctctcgctgt atgtgcatat
     9661 cccgttttgt cacaagttgt gttatttctg cggctgcaac aagattgtca cccgccaaca
     9721 gcataaagct gaccagtatc ttgacgcgct tgagcaggaa attcgccatc gcgcgccgct
     9781 gtttgcagac cgtcatgtca gccagcttca ctggggcggc ggtacgccta cttacctgaa
     9841 taaagcgcaa atcagccgct taatgacgct gttgcgtgaa aatttccact ttaataccga
     9901 cgcggaaatc tcgatcgaag tcgatccccg tgaaattgag ctggatgtgc tcgatcattt
     9961 acgtgcggaa ggttttaacc gcctgagtat gggcgtgcag gactttaata aagaggtgca
    10021 gcgcctggtt aaccgcgagc aggatgaaga attcatcttt gcgttgctta atcacgcccg
    10081 cgatatcggc tttacctcga ccaatatcga cttgatctac ggtctaccga aacagacgcc
    10141 ggaaagcttc gctttcacgc tgaagcgtgt gacggaactg aaccccgatc gtttgagcgt
    10201 ctttaactat gcgcatctgc caacgctttt tgccgcccag cgtaaaatta aagatgccga
    10261 tttacccagc gcgcagcaga aactggatat tttgcaggag acgatcgtat cgcttactca
    10321 ggccggttat cagtttatcg ggatggacca ttttgcccgt ccggatgacg aactggccgt
    10381 cgcgcagcgc gaaggcgtgc tgcaccgtaa ttttcagggc tatacgaccc agggcgatac
    10441 cgatctgctg gggatgggcg tttctgctat cagcatgatt ggcgatggct acatgcagaa
    10501 ccagaaagag ctgaagcgtt attaccagca agtggatgag cggggcaatg cgctatggcg
    10561 tggtattacg ctgacccgtg atgattgcat tcgtcgcgat gttatcaagg cgctgatttg
    10621 taacttccgc ctggatttta acgctgtcga acagcagtgg ggtttgcatt tcgctgaata
    10681 ttttgccgaa gatttgcagt tactgtcgcc gctggcgaaa gatgggctgg tggatattag
    10741 cgagaaggga attcaggtga cggcgaaagg tcgtttgctg atccgcaata tctgcatgtg
    10801 ctttgacgcg tatctgcgcc agaaagcgcg gatgcagcag ttctcgcgcg tcatttagcc
    10861 gggttgcccg gtggcgctgc gcttaccggg cctacacgtt gcgacaacct gtaggccgga
    10921 taagcattag cgccatccgg cacattgtca gctgaacagt cccaccagcg cggcacacaa
    10981 cacggcggct agcgcagttt gtggcgtgtg gctgtcgacc gctccactcg ataccagatt
    11041 aataatagat tctaacataa tgaatccccc cgtttgccgg gcatgatcat actgaactca
    11101 tcggaacagt aaagcgcaaa atagcagcgt tttgcgctca attattaatc tttacactcg
    11161 cggataatgt ttactccatt cccagctctt tcaacttccg cgttagggtg tttcgacccc
    11221 aaccgagcag cttggcggct tcctgtttat gaccctgcgt atggcgtaac gccgtggtca
    11281 gtagcgttct ttccagttct ggctgcgctt cagaaagcag gttttgatga ccggatcgca
    11341 aggcgcgatc cgcccattgc gccagtaatg tagcccagct atccggcggc aggtgggacg
    11401 ggctatccgg cgccgaggct tcaaacagtt cgcccggtaa atcctgggtc aatacctcct
    11461 gtccggcggc catgacggtg agccagcggc aggtattttc taactgacgc acgttaccag
    11521 gccatgccag gcgcgttaac gccgtttcgg tttccggatg taataatttg gcttccacgc
    11581 ctaattcacg ggcggcgacc tgcaaaaaat ggcgcgccag gcgcggaata tcctcacggc
    11641 gctcgcgcaa cggcgggaga tggatacgaa tcacgttcag gcggtggaac aggtcttcac
    11701 ggaatttccc ttcctgaacg cgtcgttcga ggttctggtg ggtggcggca ataatgcgca
    11761 catccacttt taccggcgcg tacccgccca cacggtagaa ctgtccgtca gccagcacgc
    11821 gtaacagacg agtctggaca tccagcggca tatcgccaat ttcgtccaga aacagcgtac
    11881 cgccgtcagc ctgctcgaaa cggccctgcc ggatggtatt cgccccggta aaagcgcctt
    11941 tctcatggcc aaacaattcg gattcaatca aatctttcgg gatggccgcc atattgagcg
    12001 cgataaacgg cgctttggcg cgtgggctat ggcgatgtag cgcatgggcg accagttctt
    12061 taccggttcc tgattcgccg ttaatcagca cgctaatcga agaacgcgac agccgaccaa
    12121 taatgcgaaa cacatcctgc atggcgggcg cttcgcctat catgtctgtt gtcgggccgt
    12181 taacctcgat attacgcggc tgctgctgct cctgatagtg gctaatcgct cgctcgacca
    12241 gagcgacggc ttcatcaata tcaaacggtt taggcagata atcaaacgcc ccctgctgat
    12301 aagcgctcac ggcggcatct aaatcggaat gcgcggtcat aatgatgacc ggaagcatcg
    12361 gatgacgttg tttaatctgc tttaatagcg ccagcccgtc cattcctggc attcggatat
    12421 ccgacagcaa gacgtccggc gttttactgg ccagcgcagc cagtacttca ttaccattct
    12481 caaaggtgat acaggtcaac cctgccccgg cgagagcacg ttcaagcacc caacggatgg
    12541 aactatcatc atcgacgacc cagactattc ctcgttgcat aaacacctct atttccgaat
    12601 cggcaggtaa accgaaaact cggtatgccc cggccaactg gtaaattcaa ttttgccggc
    12661 gtgttgatcg ataagattgc gggcgataga taacccaagc ccggtgccgc cttcgcgacc
    12721 gctgaccatc gggtagaaca gcgtatcctg taaatgggga ggaatgcccg gcccattgtc
    12781 ttcaacgtct atacgcgccg ccaggcgata gcgttcgcca tgcagcgtta actggaaggc
    12841 ggtacgggta cgcagcgtaa tttcgccgcc ttccggcccc agcgcctgca aggcattgcg
    12901 gacaatattc agcagtactt gctcaatttg ttccgggtcg tgcggcagtt ctggcagact
    12961 ggggtcgtaa tcgcggataa gccggacatt atccggcagt tccatcgaca ccagcgccac
    13021 cacgcgctcc gcgactttat gtatgctctc ggtaatgtgc attcccgggt gctgcggccc
    13081 cagcaaacga tcgacaaggt tgcgtagcct gtcggcctgt tcaatgatga ctttggtata
    13141 ttccgttagc gccgggtcgg gcagcgcctt gctgagtagc tgcgccgcgc cgcgcaggcc
    13201 gccgagcgga tttttgattt cgtgcgccag accgcgcacc agatcgcggg cggcgatttg
    13261 ctgcgcgtgc tgcaactgct cctgactcag acgacgctgg ttatccatcg gcgccatttc
    13321 gagcagtata aaatcgtcgg gcagacgttg ggcggtcaaa gagagaatat gcgagcgact
    13381 atcaatcacc agcgtcactt cgttatcggt aaagccttgt cctgccgcta aactttcgcg
    13441 catcaggtca atgtttaacg aaaaatagct caacagttca ggtaacggcg tcccgaacag
    13501 tttgcgtgag ctttgcgcga gcaactgctg cgcggcaggg ttggcgtaat ggattgccag
    13561 cgcgtcgtcg accaccagca cgctgttgat taacgaattg aggatctgcc cagcatcggg
    13621 ctgtatgccg cttgccattc agcagtctcc tggaaaaggt tgcaccattt tagtgcatta
    13681 tagcttttta ccactaaaaa gcgcgtgaga tcagattgtt ggtggagaaa aaagcccatc
    13741 ctgggatggg ctgaaagttt ccacggcaac tcaaaaactc ctgacgcctt tcacgctgct
    13801 gctgcgttgg ctgccttcgc ttaccccggt cacatcgcta tctatgctcc cggggatgtg
    13861 ctcagttgcc gccttgcagc aacgcgaaat tcgtcggatt tttaatatac gattaaacgc
    13921 tgtagtacag ctcaaactct accgggtgcg gggtcatacg cacgcggtca tcttcttcgc
    13981 gacgcagcgc aatatacgca tcgatcgctt catccgtgaa cacgccgcct gctttcagga
    14041 actcgcggtc caggtccagc gcgttcagcg cttcttccag agaacctgct acctgtggga
    14101 tctctttcgc ttcttccggc ggcaggtcat acaggttttt gtccatggct tcgcccgggt
    14161 gaatcttatt cttaatcccg tccagaccgg ccatcagcag ggcggcaaag cacagatacg
    14221 ggttagccgc cgggtccggg aagcgaactt cgatacggcg cgctttcgga gacgccacca
    14281 ccggaatacg gatggaggcg gaacggttac gggcggagta ggccagcatc accggcgctt
    14341 cgtaacccgg gaccagacgc ttgtaggagt tggtggtcgg gttcgccagg gcgttgatgg
    14401 ctttggcgtg tttgatgacg ccgccgatgt agtacagcgc ctgctcagac agaccggcat
    14461 atttgtcgcc agagaacagg ttggtgccgt tcttcgccag cgacatgtgg cagtgcatac
    14521 cggaaccgtt atcgccgaac atcggttttg gcataaaggt cgcggtctta ccgaagcggt
    14581 gagccacgtt atgcacgaca tatttgtaaa tctgaatttc gtcggctttt ttggtcatgg
    14641 tgttaaagcg ggtcgccact tcgttctgac ctgcggtcgc tacttcgtgg tggtgcgctt
    14701 caacaaccag gcccatctgc tccatgacca gacacatttc agaacggata tcctgcgcgg
    14761 agtcaactgg cggaaccggg aaataaccgc ctttcacgcc cgggcgatgg cctttgttgc
    14821 cgccttcgta tttggtagag gagttccagg cgccttcaat atcgtcaatc gccacatgtg
    14881 agccggagat agatgcgccg aagcggatgt cgtcgaacag gaagaattca ggttccggcc
    14941 caaacaggac ggtatcggcg ataccggtcg cgcgcaggta gtcttccgca cgttttgcga
    15001 tggaacgtgg gtcacggtca taaccttgca gagtgccagg ctccaggatg tcgcaacgga
    15061 taatcagggt agagtccgcg aagaacgggt cgataaccgc agtggacgca tcgggcatca
    15121 gcaccatgtc ggattcgtta atgcctttcc agccgccgat agaggagccg tcaaacattt
    15181 tgccttcttc aaagaattcg gcatttacct gatgagcagg aatcgtgacg tgctgttctt
    15241 tgcctttggt atcggtgaag cgcagatcga caaacttcac ttcgtgttcg ttcagcatcg
    15301 tcaaaacgtg ttcagcggac atacttgtac tctcccggat tggtcatggt cggtcgtcgt
    15361 ggtaacgaga tcttcaattc tgctggccgt gtcgccgtaa aaatataaag cgaaatctgt
    15421 gccaactttc acattgcccc ccaaaaggcg ttatcatgcg caccatcgtg caaaagggct
    15481 gcaccacggt gactatgttg caccaaaata gtgcttcaat gtgaacatta agcaccacat
    15541 tggtgcaata gaacgcaagc caccctttta acgctccgtg aaagcgatca caaagagact
    15601 ctgcaatact tgtttgcgga ggatgtttgt gatcctgttt tgtagtgcga ttaatccgtg
    15661 tacaataacg cgctatttct aatgcctgag gcaaagttgt gatcgaaaat ttgcgtaaca
    15721 tcgccatcat cgcgcacgtt gaccatggta aaactaccct ggttgataag ctgctccagc
    15781 aatccggtac gttcgacgcg cgtgccgaaa ctcaagagcg agtgatggac tccaacgatt
    15841 tggagaaaga gcgtggtatt actatcctcg ctaaaaacac cgctattaaa tggaatgatt
    15901 atcgtatcaa catcgttgat actcccgggc acgctgactt cggtggtgaa gtagagcgcg
    15961 tcatgtccat ggttgactct gtgctgctgg tggttgacgc atttgacggc ccgatgccgc
    16021 aaacgcgctt cgtgaccaaa aaagcctttg ctcatggcct gaaacccatt gtggttatca
    16081 acaaggttga ccgtcctggc gcgcgccctg actgggttgt cgaccaggta ttcgacctgt
    16141 ttgttaacct cgacgcgacc gacgaacagc tggacttccc gatcatctac gcttcggcgc
    16201 tgaacggtat cgcgggtctg gaccacgaag atatggcgga agacatgacc ccgctgtatc
    16261 aggcgatcgt tgatcatgtt ccggcgccgg acgttgacct cgatggtccg ttgcagatgc
    16321 agatctccca gctggactac aacaactacg ttggcgttat cggcattggc cgtatcaaac
    16381 gcggcaaagt gaagccgaac cagcaggtca ctatcatcga tagtgaaggg aaaacccgta
    16441 acgcgaaagt aggtaaggtg ctgacgcatc tgggtctgga gcgtatcgac agcgatatcg
    16501 ccgaagcggg cgatatcatt gcgatcaccg gtctgggcga gctgaacatt tccgacacca
    16561 tctgcgaccc gcagaacgtt gaagcgctgc cggcgctgtc cgttgatgag ccgaccgtgt
    16621 ctatgttctt ctgcgttaac acctcgccgt tctgcggtaa agaaggtaag tttgtgactt
    16681 ctcgtcagat tcttgaccgt ctgaacaaag agctggtgca taacgtggcg ctgcgcgttg
    16741 aagaaaccga agatgcggat gcgttccgtg tatccggtcg tggcgaactg cacctgtccg
    16801 tgctgattga aaacatgcgt cgtgaaggtt tcgaactggc ggtttcccgt ccgaaagtta
    16861 tcttccgtga aatcgacggt cgtaaacaag agccgtacga aaacgtgacg ctggacgtcg
    16921 aagagcagca ccaggggtct gtcatgcagg cgctgggcga gcgtaaaggc gatctgaaaa
    16981 acatgaatcc ggacggtaaa ggccgcgtac gtctcgacta cgtgatccca agccgcgggc
    17041 tgattggttt ccgttcagaa ttcatgacca tgacttccgg tacgggtctg ctgtactcca
    17101 ccttcagcca ttacgacgat attcgtccgg gtgaagtggg ccagcgtcag aacggcgtac
    17161 tgatctccaa cggtcagggt aaagcggtgg cgtttgcgct gttcggtttg caggatcgcg
    17221 gtaagctgtt cctgggtcac ggcgcggaag tttacgaagg ccagattatt ggtattcaca
    17281 gtcgctccaa cgacctgacg gtaaactgcc tgaccggtaa gaaactgacc aacatgcgtg
    17341 cgtccggtac ggatgaagcg gtgattctgg ttccgccaat taaaatgagt cttgagcaag
    17401 cgctggagtt cattgatgac gacgaactgg tagaagtcac tccaacctct atccgtatcc
    17461 gtaaacgtca cctgacggaa aacgatcgcc gccgtgcgaa ccgtggtcag aaagaagagt
    17521 aattaacgtt cttacggata aaaaccctgc cgaaatgaaa actcggcggg gtttttttat
    17581 tcacgttgag aaagggataa ggttgtcaaa aaatcagcaa tcgttggcgt attatgccga
    17641 ccaatgacgc tatccgcata cacctttgcc cgagcgctgg cattccccat cgcgacaccc
    17701 aatccggcta aacgtagcat ttccgcatcg ttatcattat cgccaaacgc catcacttcg
    17761 cgcattgcga tatgctgttg ctgtgcatat ctggcgaggc tttgtccttt gctacacccc
    17821 ttctggagaa tatccagttg atgatgccag gaccaggtac agcttagctg taattcatgc
    17881 tgtataaact cagcaatatt ttgtagttgt tttatgtgcc gatgaacgac gctgatttgc
    17941 caaatattct ccctactgct tagctcatca gcctgaaaga ttattttatc atcagcacga
    18001 attgtcggtt taagcggata tacccgcgcc agtatttttt ccgtttgtaa gtgcgtcagc
    18061 ggcagcggat caaggatctg ctgttgagcc ggttgataaa tataacttcc gttacaacag
    18121 atcatcggtt cggtgagcgc cagcgtttga taatacgcat aggcttcacg atgagagcga
    18181 ccggtgacaa gcattattcg gcagcccatg tcctgcatct gacggatagc ggttagcgac
    18241 tctggcagaa tttgtttatt acggtttagc agcgttccat caagatcaaa agcgattaaa
    18301 cgatatcgca tgagcgcccg atcctaaaac agcgtgaggc atccaggtga ttcagcaatg
    18361 gaatatcgag acggtgctga taagcgagaa aacagtggca ttgttttgcc tggcaggcag
    18421 gagaattgag ccgttgctga tataaattac ccattttaat tttgctgata tgacaagcaa
    18481 aaagatcgcc ttctgcgttc ataaaaatac tttttcttcc tgcggtacag atatccagct
    18541 gcgctggcca ctgctgcgtt tcaaccacat acagcggatc gagttcgctg aaggcgatgg
    18601 tttcctcaac ggtatgccgg gtattggcac actcgttggc gttaaaccaa aaataattct
    18661 ggtcaggcaa ccgctggcgt agccaacgaa actggtcgat atctttcata ctggcgacag
    18721 cccccgcgca ccaggttatt ccggcggcag agagcgctaa acactgctgg agaaagcgtt
    18781 cagcggtaat ttgtgaggga tgaaaagaac accataaccg aagctttgag atatctccgc
    18841 cgccagcacg aaatgactcc agcaatgaca ttaacgaaaa agaggcgtta gtttgtatgc
    18901 cgaccgcctg aacatgagga tagcggctaa tgtctgccag cgccgccatg taataacgca
    18961 agcgtagcgc ctcgccataa ggcgtaatca tcacattcaa cggcgtacct aaaagaggca
    19021 aatggtcaac catgcgccat agcgcggctt cgtcgcgttt tttatcgttg cgggcgtgtt
    19081 tatggaacgg gcaatagccg caatgataat tacacgactt aagatagccg cgataaaaca
    19141 gcgtatgaat atcgcgcagg gcggggatgc tcatctctgc cgattctccc gtagcatcac
    19201 ctcaggcgaa acgaacacag gagcaaggca atcggataat gccataccgg tctccgttag
    19261 ccggaggcga ctgccattct gataacagta gccctgccgt ataaagcgtt ccaggtcggg
    19321 gaaatccctt agcgcatcgc tggtaaaata ttgctgataa tcgctaagag aaagtccttg
    19381 ccagaaaaat agatttttaa tgataaagcg gcgtttcatt tcatcagggg ggagcagata
    19441 accgtgatta atgacggttt tgtccgggct gtcgataaac gcctgaatga tttttcgtga
    19501 tgtttgcagg ttcgacggcc acggtgaaca gtaatgcaga ttgccaagat aacttctgcc
    19561 gcccgcgccg agcgccagtg agttttcaaa tccgcagctt tccgccgcgg cggatggcgc
    19621 tggattaagg acgaaacggc gcatggacgt ttgggtgtag cccgcgttgc gtaaaagatc
    19681 gcgggctaaa acgtagtagc tatgcatatt ttcctggcga ggcatattat aaagcggata
    19741 aagaaacagc tcttccggtt gataaacgag cgcctgatgt aacgattccg tcaggcttgc
    19801 gtgagtctgg ccgggaatgc cgtaaataat atcaatattg agtgatggaa aatgacctgc
    19861 ctttagccat tccaacgcct ggtgcgcgct ggcggtattg tggcggcgat gcagcgtatg
    19921 taactcgcta tcatgaaaac tttgtacgcc aatactgacg cgattaacgg aaaaggcgtt
    19981 taatagcgct actttttctg ccgtggtatc cgtaggggaa gtttcaattg ttttataaat
    20041 attccagtca acattgagca catcaaagac ggaaaaaaat aacttttcta attgcgcaat
    20101 gtttaatagc agaggtgtgc cgccgcctac ggtgaagctt gcccagtgga cgggcgccag
    20161 cgccatttgt cggccctagg taataatcgc gtcgatatag ctatcaatga acgtattatc
    20221 tgcgccagtg caggtaaata aattacagaa cccgcagcga ctttgacaaa acggcatatg
    20281 aacatacaga tgtgtgtcgt gctcgtaaat gcgcggtttt actttgctaa agctgacgtt
    20341 ctccagctcc cgataagccg tcttatgcgg ataactgtac atatactgac gataaatatc
    20401 attgttattc atattaatga ttaccgctca ataagaaatg catataagga acggtattaa
    20461 cgatcggatg attaaaacta tggaaatatt tcccgtcttc gccatagcag gtaccgtgat
    20521 cggaacagac aataacgaac gtttcgccgc cggtttggcg gaaaatgttc agtaatccgt
    20581 cgatgcgggc gtcgatatag cgtagcgcgg cggcatgggc ctctacggta tcgccagggg
    20641 ccgcgccctc aacgtaaaaa tggttagggt aatgaatcgt atcgatattg atatacatca
    20701 tgaccggttg gctgccagca cgttcggcca tgattttctg gatataatgg atctggttat
    20761 ccatactttc tttaaccgta caggcaaagc gtggatgcca gtaactctct ttaaacatcg
    20821 acgggaacac ttttcccatg ccggagcggt tattaaagaa agagacgccg ccaatacaga
    20881 tggtctggta gcctttattt tccagacttt ttatccatgt tgcgtcatca aaggcaaatg
    20941 catttttcgg gcctttacga ccaagtccga tatcttttgg gaaaagcagc atggtctgat
    21001 taacggtatc atcaataggt tttggcataa aacctgaaaa catggcgtga tgcgaaggcc
    21061 aggtaaaatt accggccgcc tcgcatttcg tccattgtcc ataatgatta aggttgggcg
    21121 tatttccggc ggtttgttcc tgaagcgcaa tatcgtagcg taacgagtcc agtacaataa
    21181 aaagaatatg agcgttatta ctaattagcg cattcatatc gaattcgcca tcgcctgtgt
    21241 caatcgacgc gtgtagcgag acggggactt catccattga attatacatt ttgcttcctc
    21301 atggcccgga tttgcgcctg ataaattaga ttgttctgct gcgcatcctg ataaatcaaa
    21361 tcaccctggc cattaatttc aataatatac ggcgtcaggc tggtggtaag taaaacatca
    21421 atacccgcta agcgaatgcc aggaaaaagc cgcatggcat tttgacagag cgtatcgatc
    21481 tcagccactt ttgcggcaga taactccaga ctttcgaagc ggtaagcctg gttttgcagg
    21541 tgtaagttag taatgggctg cgaggaggtt ctgaccactc gccagataat ttcgccatcc
    21601 agacagacga tgcgtaaatc ataggtttta tgctttacgc tggctttggg cagccactgt
    21661 tcgacgaggt tttcctgctg aagaacgcca tcaataatga gctggatatc ttctttctga
    21721 cgatactgtt ggattttttt gctgttaaat agctgttgcc ctgatatggc aatcgcgctg
    21781 taaagcacct gctttgcgcc gtcaggatga cggcgcaaag cgataacgcc cgccgcgcca
    21841 aaacccagcg agggcttaat gaacacgctg gcgacccttt tttcctccat gatggcggtg
    21901 agctgtgcaa aactttttac gtcttccgct accaacggcg gcgtggggat gccgtgttcc
    21961 agtaagcgcc gcttgcagcg ttttttatcc aacaggtgaa tgaggcccgc cggatggtta
    22021 agctaggtga tgccaggacg cgctgccatg ttctgcaaaa aatggatata gtccagaccg
    22081 atcgcgttta ttttgcggat gttagtttca ttgtgtactg gcgggtcgat tttaacgatg
    22141 ccagaggtca gcgaagcgtc cagcgcttgc ggatgagtca gcgccgtgac ggattcccca
    22201 agtatggcgg cagcctgcat aaaataatgc gtgcgcttgc tctgatgggg gccaatgagc
    22261 gtaatcacaa taaatccctt tatcggtgtg taggggaatg tgcacattcc cctacacaat
    22321 cactcggtgt acatcgcatt catataaata tcgccatcgt aatcatcagg ctccagcgct
    22381 tctgaaagat tcagcggtat cggcagcgcg gcttttagct tttcctgcat ctccggcgtc
    22441 aaatagtggt ggtggagatc gagtgtttcc agatgcgcaa ttcggtcttt atgctccagc
    22501 agcgcctctg cgccgctatc agttaaggta ccgcatgaga gttccagcac gttaagctgc
    22561 ggcaggatat tactttccag cacccggcgg gcgatatcat cctgctcttc actgttcatc
    22621 aaccccagat ggttgagctg agggaaaaga tctttcgata ccagcgccat cacgttatcc
    22681 agcgaaccgt caaaaccgta ttcctctacg cccaggaaga gcttcagcgt ttttaatgca
    22741 gggagctgcg cattttgtag ttcggcaagt acgttagaag ggatgccgcc ggaaatgatt
    22801 tccaggtgct ccagtttctc atgatgtata gcgcccagtc gcagatccga cgcgccttta
    22861 ataatcagtt ccttcagatt gggtaacgcc gcatagagcc tggaatagtc accttgttta
    22921 atccaggaga tctcgcagtc ttcgctctcc atatcaccga taaacagtga ttccaggtga
    22981 gaaaaacggg gggcgttctc cacaatcata tcaataatag gctggcaggt ttcgtcttcc
    23041 caacaatcac cccagttacc aatggtcagt gagcgaagct ttggcagatc ttcatcggtt
    23101 aaaattaaat taatgagctg ttcctgggtt aattcattgt cccaatcaat attgaatcgc
    23161 ttattcattt gtttcccttc tctataagca tgaatatggt aaaacgcttt gcgaatatta
    23221 tcatggcgct tagaggcggg atatcgggag tctgattcag gatgaatgag cgggcagaac
    23281 aactacccgc tgtgatgcag attcggaaaa tagaggcgat aatatcagaa gaaatacttc
    23341 gccccgatac gaatctggtt ttgctctcta tggtagaggc ccacgttacg atctaaccag
    23401 cgtaattcaa agtagggcaa ccagtgttca ttgatacgat aacggaaggt attagtgatt
    23461 tcccaatgat gcttcgtacc attactacta ttaaaatcat taacgttata aaaatagtgt
    23521 ggttcaaagg tataagaaaa tttatcggta atgataaaat tccaatagtt accgatttca
    23581 tagctgtcat tattatccag ttcgccattc aaatcggttg aactataatt attgtgatta
    23641 tatcggttac gtaccgtaag attaaaccac ggggtaaatt tatagttaat atccagatag
    23701 acggcgccgc cggaaccaat gcttttgtcg tttattaacc cgcctggctg gatggttaat
    23761 ttatctgtag gtttaaataa cggataccag ccctcaatct cattataacc gtgctttaat
    23821 tcatcatcac gctgtagcgt ataggtattg gtcaacataa ttccggcccc catatcggag
    23881 ttatagccga cgcgcagcat aaactccatt tggtcagacg ccaggttata ggcctcacgg
    23941 ttttctacat aagcgccagc aaaaacagag gtgga
//
LOCUS       DAJVKX010000062        23624 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000062 DAJVKX010000000
VERSION     DAJVKX010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23624
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.062"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..141
                     /locus_tag="OPY25_002550"
     CDS             <1..141
                     /locus_tag="OPY25_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HCS0928141.1"
                     /translation="ARVSNKVGLESDAQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVL
                     AM"
     gene            276..1895
                     /locus_tag="OPY25_002551"
     CDS             276..1895
                     /locus_tag="OPY25_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCS0928142.1"
                     /translation="MFIREITHWFARRSFQNRIFLLILFTSTIVMLAITWYLTDITKE
                     RLHYQVGQRALIQAMQISAMPELVEAVEAHDLSRIKALIDPMRSFSDATYITVGNEKG
                     QRLYHVNPDEIGKYMEGGDSDDALYNAKSYVSVRKGSLGSSLRGKSPIQDSTGKVIGI
                     VSVGYTLEQLESWLNLQISSLLFPMAILLLVLLYCARRFSLHIKKQMLNMEPQQLSQL
                     LIQQSVLFESVFEGLIAIDSHHRITAINQTARRLLNLSQPESELIGYAIHHIVLPEAF
                     FYDAPQKNKKDEIVTFNQMKVIASRMAVIIDNQPQGWVISFRNKDDINTLNLQLSQVR
                     QYADNLRAVQHEHRNLISTIAGLLFLKRYDNALALIQQQSESHQKVLDFISHNFRDHH
                     LAGLLIGKYYRAKELGLELIFDPSSFVEHLPSSLSHNEWISIVGNLLDNAYNATLLNR
                     EGSRQIECLINSEGNEVIIEVADQGCGIDENIRQHIFERGVTTHNNGDHGIGLWLVHS
                     YVKQANGDIIVDNNNSFGTIFTLYIPFTREE"
     gene            1897..2583
                     /locus_tag="OPY25_002552"
     CDS             1897..2583
                     /locus_tag="OPY25_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCS0928143.1"
                     /translation="MDSITTLIVEDEPMLAEILVDTIKLFPQFSIVGIADKLESAKKQ
                     IRLYQPQLILLDNFLPDGKGIDLIRHTISTNYTGRIIFITADNHMDTISDALRMGVFD
                     YLIKPVHYQRLQHTLERFTRYRSSLRSSEQANQTHVDALFNIQAKEQTAEPNSGLRGI
                     DENTFNRVRQIFADPQAVHTADTLAQILGSSKTTARRYLEQGVKNNFLEAEISYGKVG
                     RPERLYRGKV"
     gene            complement(2605..3525)
                     /gene="rihC"
                     /locus_tag="OPY25_002553"
     CDS             complement(2605..3525)
                     /gene="rihC"
                     /locus_tag="OPY25_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HCS0928144.1"
                     /translation="MTASLHIILDTDPGIDDAAAIAAALFAPQLDLQLITTVAGNVSV
                     EKTTRNALQLLHFWNSDIPLAQGAATPLLRPLRDAAYVHGESGMEGYDFVDHQRQPLA
                     KPAFIAIRDVLMNAPEPMTLVAIGPLTNIALLLMHYPECACNIRRLVLMGGSAGRGNF
                     TPNAEFNIAVDPEAAALVFRSGLEIVMCGLDVTNQAMLSPDFLNKLPALNRTGKMLHS
                     LFNHYRSGSMRTGVRMHDLCAIAWLVRPELFTLQSCFVAVETQGEYTAGTTVVDIEGR
                     LGQPANAQVALALDVDGFRQWGAEVFAYVP"
     gene            complement(3541..4743)
                     /locus_tag="OPY25_002554"
     CDS             complement(3541..4743)
                     /locus_tag="OPY25_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase"
                     /protein_id="HCS0928145.1"
                     /translation="MGKIKYRLPTLLAIGFWMDAASATVLELPAWERNYTGTIAGKPV
                     NVNITRFGNTLYGHYCYEPCNQHKAVIVLRGSLQDKEVHLEERVKALSGYWNAEISSS
                     EIKGEWTSADKKRHFPVALIYYKPKNSPDIVLVTNTNDAGGYDPSKEIDCGNTPAISA
                     IKLYRDGKLIQTLDTASVGTCSPFMPQWGDVNFDGYPDLSIVTELLAGPDAPVQTWLY
                     DPAKQRYVDAPASYQEITSPEIDAEHKQIVSYWRGGCCSHGVNVYRWKGKTIELIDRG
                     ESYFQPVISKGKMYNCYMTPSYADGRIIYPLVRKNGHLTPPLSLDGTCQSFWLTGNVR
                     TVIQAEKPGAEPESLEIQWQENKASPGRFCPLVPFVEGDKLSPRLVTDDDVPDTCISR
                     AEYEDIKQ"
     gene            complement(4943..5893)
                     /gene="ispH"
                     /locus_tag="OPY25_002555"
                     /gene_synonym="lytB"
     CDS             complement(4943..5893)
                     /gene="ispH"
                     /locus_tag="OPY25_002555"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HCS0928146.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRQRGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPEDVWTLNVKNEGK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQADVVL
                     VVGSKNSSNSNRLAELAQRMGRTAFLIDDAADIQEAWVKDAACVGVTAGASAPDILVQ
                     NVIARLREFGGGEAVTLEGREENIVFEVPKELRVDVREVE"
     gene            complement(5896..6345)
                     /gene="fkpB"
                     /locus_tag="OPY25_002556"
     CDS             complement(5896..6345)
                     /gene="fkpB"
                     /locus_tag="OPY25_002556"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCS0928147.1"
                     /translation="MSKSVQSNSAILVHFTLKLDDGSTAESTRNNGKPALFRLGDTSL
                     SEGLEQQLLGLKEGEKKAFSLEPDAAFGVPSPDLIQYFSRREFMAAGEPEVGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGHTVHFDIEVLEIDPALEA"
     gene            complement(6500..7000)
                     /gene="lspA"
                     /locus_tag="OPY25_002557"
     CDS             complement(6500..7000)
                     /gene="lspA"
                     /locus_tag="OPY25_002557"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCS0928148.1"
                     /translation="MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFP
                     SLNLHYARNYGAAFSFLADSGSWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKP
                     TAKEQA"
     gene            complement(7000..9834)
                     /gene="ileS"
                     /locus_tag="OPY25_002558"
     CDS             complement(7000..9834)
                     /gene="ileS"
                     /locus_tag="OPY25_002558"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCS0928149.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGFDSPYVPGWDCHGLPI
                     ELKVEQEFGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGRIIKNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFRAVD
                     QDAVKAKFGLPGVSGPVSLVIWTTTPWTLPANRAISLAPDFDYALVQIDGQAVILAKD
                     LVESVIQRIGAAEYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGAYLPGTYPTLDGVNVFKANDIVIELLKEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDKEGLRQQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKETQELLPIERTLAAMEEVAKRVEVDGIQ
                     AWWDLDPKEILGEDADQYEKVPDTLDVWFDSGSTSYSVVDARPEFAGHAADMYLEGSD
                     QHRGWFMSSLMISVAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGA
                     DILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFNPATDMVKPEE
                     MVVLDRWAVGCAKTAQQEILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTA
                     KADSVARRSCQTALYHIAEALVRWMAPIMSFTADEIWGYLPGEREKYVFTGEWYDGLF
                     GLEENEEFNDAFWDDVRYIKDQVNKELENQKANGIKSNLEAKVTLKYADDANGTIKKL
                     KLLGEEVRFIFITSQFVISEQAGGIDDENIQYNAGNTTVQAVVTRAEGDKCPRCWHYT
                     TDVGKVAEHADICGRCVSNIAGNGEQRKFA"
     gene            complement(9879..10817)
                     /gene="ribF"
                     /locus_tag="OPY25_002559"
     CDS             complement(9879..10817)
                     /gene="ribF"
                     /locus_tag="OPY25_002559"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HCS0928150.1"
                     /translation="MKLIRGIHNLSQAPHGCVLTIGNFDGVHRGHRALLQGLQEEGRR
                     RGLPVVVMIFEPQPLELFATDKAPARLTRLREKLHYLAQCGVDYVLCVKFDRRFAALT
                     AQTFISELLVERLGVQFLAVGDDFRFGASRAGDFLLLQKAGAEYGFAVSSTQTFCEGG
                     VRISSTAVRQALAEDNLALAESLLGHPFTISGRVVHGDELGRTIGFPTANLPLRRQVS
                     PVKGVYAVEVTGLGDKPLPGVANIGTRPTVAGVRQQLEVHLLDVVMDLYGRHIDVILR
                     KKIRNEQRFASLDELKAQIARDELTARKFFGLAGQV"
     gene            complement(10825..11040)
                     /locus_tag="OPY25_002560"
     CDS             complement(10825..11040)
                     /locus_tag="OPY25_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 domain-containing protein"
                     /protein_id="HCS0928151.1"
                     /translation="MQHSLRSDGAGFYQLACCEYSLSMRKIALSGGFWGGVCRMAMKS
                     IFFMFHQGNRRLTLTAVQGILLRFSLF"
     gene            11146..11409
                     /gene="rpsT"
                     /locus_tag="OPY25_002561"
     CDS             11146..11409
                     /gene="rpsT"
                     /locus_tag="OPY25_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCS0928152.1"
                     /translation="MANIKSAKKRAVQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAALKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     gene            11463..11708
                     /locus_tag="OPY25_002562"
     CDS             11463..11708
                     /locus_tag="OPY25_002562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928153.1"
                     /translation="MPAICRFSRQPLALTSLVHALPVPAYFFSYPSLSHVILESYFLS
                     LFSFSYFITEKTVTTLANKNIAHLKTNKRNPDVRFNN"
     gene            11866..13239
                     /locus_tag="OPY25_002563"
     CDS             11866..13239
                     /locus_tag="OPY25_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928154.1"
                     /translation="MSSVIEDTQPSGSASLSLLQRISYGSLDVAGNLLYCFGSTYILY
                     FYTDVAGISLAVAGIILLLARIVDGIDAPIWGIIIDKTRSRYGKCRPWFLWLPLPFAV
                     FSALSFWSPDISITGKAIYAAISYMIASILFTGLNTPLSAILPLMTLSPKERLVLNSW
                     RMTGGQIGVLLMNATALPLVAFLGNGDDHAGFIYTAITFAIISCALTLFAFKNIREMD
                     ADKIQHEPKLPMKKSFAAMKGNWPWILMVLANLIFWIALQQRSTTIVYYLTYNLDRKD
                     LVPLINSLATIQILFIIAIPFFSKYLAKTWIWVGGLLVATFGGVMMWLAADNITFLIA
                     AWILGNIGSGIACSMPFAMLGFAVDFGAWKTGIKATGILIAFGSTFCIKMGSGLGTAL
                     AAWIMNSFGYVPNHAQSAAGLEGITWAFIWAPALLFALAAIPLLFFRKYEAMEEKIRH
                     DLETINS"
     gene            13279..15318
                     /locus_tag="OPY25_002564"
     CDS             13279..15318
                     /locus_tag="OPY25_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HCS0928155.1"
                     /translation="MPFMQQDPRRLVWQQNDRYLWIEPWGENSLRVRSGRHLPVMRNE
                     DWALTEPVAESQCHIDYEHHQATLTNGKIIAIVNQKGQVTFYRHPHKPLLQEFWRLRG
                     EIGEDESSHGQYVSALNLEGREFRPIQGGKYSLKARFEATEGEKIYGMGQYQQANLDL
                     KGCVLELAQRNSQASVPFMLSSLGYGFLWNNPAVGRVTFAQNVTEWEAQVSEQLDYWI
                     TAGDTPAEIGRAYALATGTPPMMPDYAMGFWQCKLRYRTQEELLEVAREYKRRNLPIS
                     VIVIDFFHWPNQGDWMFDARDWPDPDAMIAELKSLGIELMVSVWPTVDNRTESYREMR
                     ENGWLVQTERGLPINMDFLGNTTYFDATHPGARDYVWGKAKRNYHDKGVKLFWLDEAE
                     PEFSVYDYDNYRYHAGPVLEVGNIYPRMYAKTFFDGMKADGEDQVINLLRCAWAGSQK
                     YGALVWSGDIHSSFRSLRNQFAAGLNMGIAGIPWWTTDIGGFHGGNIHDPKFHELLIR
                     WFQWGVFSPVMRLHGNRDPQILPAQPYRDGIAQCPTGAPNEVWSYGEEVCDVLTGCLA
                     LREKLKPYIKALMEETHKHNTPVMRPLFFEFPEQETSWTITDQYCFGPDLLIAPVMHE
                     GMRERDVWLPEGETWTDLATGESYSGGQTLHYATPLNRIPVFIREGGQYRSLLNL"
     gene            complement(15373..16272)
                     /gene="nhaR"
                     /locus_tag="OPY25_002565"
     CDS             complement(15373..16272)
                     /gene="nhaR"
                     /locus_tag="OPY25_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HCS0928156.1"
                     /translation="MSMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKAL
                     EERLQGKLFKRKGRGLEPSELGELVFRYADKMFTLSQEMLDIVNYRKESNLLFDVGVA
                     DALSKRLVSSVLDAAVVVDEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
                     GLFSVKIGECSVSFWCTNPLPEKAFPACLEERRLLVPGRRSMLGRKLLNWFNSQGLQV
                     EILGEFDDAALMKAFGATHDAIFVAPSLYSLDFYADESVIEIGRVENVMEEYHAIFAE
                     RMIQHPAVQRICNADYSALFKLQ"
     gene            complement(16334..17500)
                     /gene="nhaA"
                     /locus_tag="OPY25_002566"
     CDS             complement(16334..17500)
                     /gene="nhaA"
                     /locus_tag="OPY25_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HCS0928157.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAALAMLMANMGATSGWYHDFLET
                     PVQLRVGALEINKNMLLWINDALMAVFFLLIGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYSDPVTREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTSDLSIVSLGVAAFAIAVLALLNLCGVRRTGVYILVGAVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTMDGLTSMLPLGIIAGLLIGKPLGISLFCWLALRFKLAHLPQGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGNIDPELINWAKLGILIGSLLSAVVGYSWLRARLNAPA"
     gene            complement(17663..19378)
                     /locus_tag="OPY25_002567"
     CDS             complement(17663..19378)
                     /locus_tag="OPY25_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCS0928158.1"
                     /translation="MNTLTATSVVLPAPRPAINQGIDINNEMVLNHTAIYENCLAQVT
                     QENTVENALMLLDPYGTAPLSAYAGVWSLEPAEIMVTVQDAAKTAMPVEHLYTLTAGA
                     NLLPVLGLVAETENRIVFSQADTPLAVYTLTTQPLPPVDSAEVVLGFPIINVTQPATD
                     VDKMAPGFYFVTHFDRYNYALDQNGLVRWYVTQDYPSYNFVRIDNGHFLTTSEAKNTY
                     LDMYEFDMMGRLHTFYNLDNQFHHSIWPWDSNTIVAPSEYTSGRPDDLKTNEDGVSVV
                     DLATGLETAYYDMAKVLDTTRVSRPSGTAPGEDPTVKDWLHINQSYVNETNQLLIASG
                     RHQSAVFGVDLQTQALRFILSTHEDWDDAYQPYLLTPVDSEGVALYDFSKQEDIDAAD
                     RDFWTWGQHNVVEIANNTPGIVEFMVFDNGNYRSRDDSKSLLPPDNYSRIVHFVVNMN
                     EMTVMRPFEYGKELGARGYSSCVSAKAIQQNGNIVVHFADCTFDENGRAISCQPGESD
                     IIDPQAGSEAMGLLILQEIAPTEKTVLFEATMTSGYYKNAETNGEGYRYDITSFRVYK
                     MDLYA"
     gene            complement(19505..20757)
                     /locus_tag="OPY25_002568"
                     /pseudo
     CDS             complement(19505..20757)
                     /locus_tag="OPY25_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(20776..21966)
                     /locus_tag="OPY25_002569"
     CDS             complement(20776..21966)
                     /locus_tag="OPY25_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HCS0928159.1"
                     /translation="MMFGKSCQVMVKPTGSVCNLDCKYCFYLEKEKLYPDRKNHYKMS
                     EETLELFIRQQIAAQDIDEVIFAWQGGEPTLMGIPFYRKAVEFQQRYCGGKTIVNTFQ
                     TNGILINDDWATFFREHDFLVGVSIDGDAALHDEWRVTRSGKPTHEKVENAVRCLAQH
                     DVEFNTLTVVNRTNMHHPVQVYRYLKSVGSRYMQFIPLVERCGENGLAQPQDKHIAMT
                     PWSVDSLQFGQFLNAVFDIWIREDIGDIGIQLFEQTLAAWCGLPPQVCVFAPTCGSAF
                     AMEMNGDVYNCDHFVYPQFKLGNIHQKTLRQMNQGEQNRQFGSDKQRSMAQECHRCQW
                     KFACYGGCPKHRFLPSASGATNHNYLCAGYQAFFSHTATAMSAMRTLYEKGISLAEIK
                     SIFV"
     gene            complement(22065..23558)
                     /locus_tag="OPY25_002570"
     CDS             complement(22065..23558)
                     /locus_tag="OPY25_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HCS0928160.1"
                     /translation="MKRTVVASMIGLALCAGCVLSTAQAATAKRPNLVIILADDLGYG
                     DLATYGHRIVKTPNIDKLAQEGVKFTDYYAPAPLCSPSRAGLLTGRMPFRTGIRSWIP
                     EGKDVALGRNELTIANLLKQQGYDTAMMGKLHLNAGGDRTDQPQAKDMGFDYTLVNPA
                     GFVTDATLDNAKERPRYGVVHPTGWIRNGQHIGRADKMSGEFVSSEVVNWLDNKKDDN
                     PFFLYVAFTEVHSPLASPKKYLDMYSQYMTDYQKQHPDLFYGDWADKPWRGTGEYYAN
                     ISYMDEQVGKVLDKIKAMGEEDNTIVIFTSDNGPVTREARKVYELKLAGETDGLRGRK
                     DNLWEGGIRVPAIIKYGKHIPQGMVTDTPVYGLDWLPTLANMMDFKLPTDRTYDGQSL
                     VPLLKDKTLKRQKPLIFGIDMPFQDDPTDEWAIRDGDWKMIIDRQNKPKYLYNLKTDR
                     FETLNQIGKQPQIEKQLYGKFLKYKKDIDNDSLMKARGDKPTPVTWG"
BASE COUNT         5855 a         6457 c         5694 g         5618 t
ORIGIN      
        1 gcacgcgtat cgaacaaagt gggcctggaa tcagacgcgc agaacttcct gctgatgcac
       61 gcgatgggcc cgaacgtggc cggggtgatt ggctcggcga tagccgccgg ggtgatgctg
      121 aaatacgtgc tggcgatgta atagtggatg ggatacgcat gtcgtatccc attttcatcc
      181 aaattttttc tgaaagaaaa gtaagtatga actggttcag gttccggtga tgccgaatgc
      241 aagaaaatac cgtaattaaa tatctaaata ccaatatgtt tatacgggaa attacacact
      301 ggtttgccag acgctcgttt caaaaccgga tatttctact gatcctgttt acatccacca
      361 tcgtgatgct ggcaatcacc tggtatctga ccgatatcac gaaagagcgc ctgcattatc
      421 aggtgggcca acgtgcgctt attcaagcaa tgcaaatatc cgctatgcca gaattagttg
      481 aagccgtaga ggcgcatgat ttgtcacgca tcaaagcgct gattgaccca atgcgctcgt
      541 tttcggacgc gacttacatt accgttggca acgaaaaagg tcagcgactg tatcacgtca
      601 acccggatga gatcggcaaa tatatggagg gcggcgatag cgacgacgcg ctgtataatg
      661 ctaaaagcta cgtatcggtg cgcaaaggtt cattaggctc ttccttgcgt ggtaaatccc
      721 cgattcagga cagtaccggt aaagtcatcg gtattgtttc cgtcggctat actctggaac
      781 agttggagag ctggcttaac ttacaaatca gctcgttgct gttcccgatg gcgatactgt
      841 tgctggtgct gttgtactgc gcccgccgct tctcgctgca tattaaaaag cagatgctta
      901 acatggagcc gcagcagctt tcacaactat taattcagca aagcgtgtta tttgagtcgg
      961 tatttgaagg gttgatcgcc attgactccc atcaccgtat taccgccatt aatcaaacgg
     1021 ctcgccgctt actgaatctg agccaaccgg agtctgaact cattggctat gcaatccacc
     1081 atatcgtgtt gccggaggcc ttcttttacg atgcgccgca aaaaaacaaa aaagatgaga
     1141 tcgtcacttt taaccaaatg aaagtcatcg ccagtcgcat ggcggtcatt attgacaacc
     1201 agcctcaggg ctgggttatt agctttcgca acaaagacga tatcaataca ctcaacctgc
     1261 agttaagtca ggtgcggcaa tacgccgata acctgcgcgc cgtgcagcat gagcatcgca
     1321 accttatttc caccattgcc ggactgctgt tcctgaagcg ctacgataat gcgctggcgc
     1381 tgattcagca gcagtcggaa agccaccaaa aagtactcga ttttatttcc cataatttcc
     1441 gcgaccacca ccttgcgggg ctattaatcg gtaaatatta tcgggcaaaa gagctggggc
     1501 tggagctgat tttcgatcct tcaagctttg ttgaacacct gccgtcatcg ctctcgcata
     1561 atgaatggat ttcgattgtt ggcaatttat tggacaacgc ctataacgcc accctgctca
     1621 atcgcgaagg ctcgcgacag attgagtgcc tgatcaatag cgaaggtaat gaagtcatta
     1681 ttgaagttgc cgatcaggga tgtggtattg acgaaaatat ccgccagcat attttcgagc
     1741 gtggagtgac cacccacaac aacggcgatc acggaattgg attatggttg gtgcacagct
     1801 acgtcaagca ggccaatggc gacattatcg tcgataacaa taattctttt ggcaccattt
     1861 ttaccctcta tatccctttt accagagaag aataacatgg atagcattac gacactcatc
     1921 gttgaagacg aaccgatgct agcggaaatc ctggtggaca ccatcaagct ttttcctcag
     1981 ttttcaatcg tcggtatcgc agacaagctg gaaagtgcga agaagcaaat acgcctctat
     2041 caaccacagt taattctatt ggataatttt ttacccgatg gcaaagggat cgatttaatt
     2101 cgtcatacca tcagcaccaa ctacacgggg cgaattattt tcattaccgc cgacaatcat
     2161 atggatacca tcagcgatgc cttacgcatg ggcgtattcg attatctgat taagccggta
     2221 cattatcagc gcctgcagca taccctggag cggttcaccc gttaccgcag ttcgttacgt
     2281 tccagtgagc aggcaaacca gacgcacgtt gatgccttat ttaatatcca ggccaaagaa
     2341 caaaccgcag aaccgaatag cggactgcgg ggaattgatg aaaacacctt caaccgggta
     2401 cgacaaatat tcgccgaccc gcaggcagta catacagcag acactctggc gcaaattctg
     2461 ggcagcagta aaaccactgc ccgacgctat ctggaacaag gcgtgaaaaa taactttctc
     2521 gaagcggaga tcagctacgg gaaagtgggc aggccggaga gactctatcg cggcaaagta
     2581 tgagattatg gcgccaacat gtaattacgg cacataggca aacacctcag ccccccactg
     2641 acgaaaaccg tccacatcca gcgccagcgc cacctgcgcg ttggcgggct gccccagacg
     2701 cccttcaata tcaacgaccg tcgtgcctgc ggtatattcc ccctgcgttt ctacggccac
     2761 aaaacaggat tgcagggtaa aaagctccgg acgcaccagc caggcgatcg cacagagatc
     2821 gtgcatccgg acgccagtgc gcatactacc gctgcgataa tggttgaaca ggctgtgcaa
     2881 catcttaccg gtgcgattca gcgcaggcag tttattcaga aaatctggcg agagcattgc
     2941 ctgattcgtg acatcaagcc cacacatcac aatctccaga ccgctgcgga acaccagcgc
     3001 cgcggcctcc ggatcgacag caatgttaaa ttcagcatta ggcgtaaaat tgccgcgccc
     3061 tgcggaaccg cccatcaaca ccagacggcg aatgttacac gcacactccg gatagtgcat
     3121 cagtagcaac gcaatattgg tcaatggccc aatcgccacc aatgtcatgg gctccggggc
     3181 gttcatcaac acatcccgga tagcgataaa cgcaggcttc gccaacggtt gacgctgatg
     3241 gtcgacaaaa tcatagcctt ccataccgga ttcgccgtgg acgtatgccg catcgcgtaa
     3301 cggacgcagc agcggcgtcg cggccccctg ggcaagtggg atatcgctgt tccagaaatg
     3361 cagaagctgc aacgcattac gggtcgtttt ttcaacggaa acattgcctg cgacggtggt
     3421 tattagttgc agatcaagct ggggggcgaa cagcgcagcg gcaatcgcag ccgcgtcatc
     3481 aatgcccgga tcggtatcaa gaataatgtg tagggatgct gtcattaacg ctctcctgac
     3541 ctattgtttt atatcttcat actcagcgcg actgatacag gtatcaggca catcgtcatc
     3601 cgtcaccaga cgcggactta gcttatcacc ttcgacaaac ggaactaatg ggcaaaaacg
     3661 ccctggcgat gctttgtttt cctgccactg aatctcaagc gattcgggct cagcgccggg
     3721 tttttctgcc tgaatcacgg tacgaacatt accggttagc caaaaagatt gacacgtccc
     3781 atcaaggcta agaggcggcg tcaaatgacc atttttacgt actagcggat aaataatacg
     3841 cccatcagcg taggaaggtg tcatgtagca gttatacatt ttgcctttac ttatcacagg
     3901 ctgaaagtag ctttcaccgc gatcgatcag ttcaatcgtt tttcctttcc agcgatacac
     3961 attgacgcca tggctgcagc aaccgccgcg ccaatagctg acaatctgtt tatgttcagc
     4021 atcgatctct ggtgaagtga tctcctgata agacgcgggc gcatcaacat aacgctgctt
     4081 ggcggggtca tagagccatg tttgtactgg agcatccggc ccagcaagta actctgttac
     4141 aatcgataga tccgggtagc catcaaaatt gacatccccc cattgaggca taaacgggct
     4201 acaggtgccc accgaggcgg tatctaaggt ctgtatgagt ttaccatcac ggtataattt
     4261 tatcgccgaa atggccggcg tattgccgca atcaatctct ttggaagggt cgtaaccccc
     4321 tgcatcattc gtgttcgtga ccagcacaat atcaggggag tttttaggtt tgtaatagat
     4381 aagggcaaca ggaaaatgtc gttttttatc tgcggacgtc cattcgcctt taatctcact
     4441 gctggagatt tccgcattcc agtaacccga aagcgccttt acgcgttctt caagatgcac
     4501 ctctttatcc tggagtgagc cgcgtagaac aatcactgcc ttgtgctgat tgcaaggttc
     4561 atagcagtaa tgcccataaa gcgtgttacc aaatcgcgtg atattaacgt ttaccggttt
     4621 ccccgcgata gtcccggtat agtttcgctc ccaggcgggt agctccagca ccgtagcgct
     4681 tgccgcgtcc atccaaaagc cgatggcgag taacgttggc aatctatatt ttattttgcc
     4741 catttccctt atccctgtag gcattacaac ccaaaaacca gcaacgattg tgctggtttt
     4801 tcagatgaat agcaaaaagg tggggcatta gcaccggatg acgactacgc cttatttttc
     4861 ctgtcgcaca ttgaatatca aaagaaattc ttaagatctg gtcagcgtag catcatcggg
     4921 cagatttctg aattgtgaaa tcttattcga cttcacgaac atccacacgc agctctttcg
     4981 gtacttcgaa aacaatattt tcttcgcgac cctcaagcgt gacagcttcg ccgccgccaa
     5041 actcccgcag acgcgcaata acattctgca ccagaatatc cggcgcggaa gcgccagcgg
     5101 tgacgccgac acaggcggcg tctttcaccc acgcctcctg gatatccgcc gcatcgtcga
     5161 taagaaacgc ggttcttccc atccgttggg ccagttccgc caatcggtta gagttagaag
     5221 agtttttcga gccaaccacc agcactacgt cagcctgctc agccagcgcc cgcaccgctt
     5281 cctgacgatt agtagtggca tagcaaatat cgtctttgcg cgggccgacg attttcggaa
     5341 agcgtttacg cagcgcatca atcacatcgg acgtatcgtc cacggaaagc gtggtttgcg
     5401 tcatgaagga gagcttgcct tcatttttga cattcagcgt ccagacgtcc tctggcgact
     5461 ccaccaggta catcccccct tccggattgc tgtactggcc catggtgcct tccacttccg
     5521 ggtgcccggc gtggccgatg agaatagatt cttcaccgcg acggctggcg cgcgccactt
     5581 ccatatggac tttcgtcacc agcgggcagg tggcgtcaaa aacggtaaga tcgcggcttt
     5641 tcgcctcgtt acgcaccgcc tgggaaaccc catgagcgga gaagatcaga atggcgccat
     5701 ccggcacttc gctaatttgc tctataaaga tcgctccgcg ctggcgcagg ctgtccacta
     5761 catagcggtt atgcacgact tcgtgccgaa cgtaaattgg cgcgccgtaa atggcgagcg
     5821 cattttcaac aatgctgata gcgcggtcta ccccggcgca aaaaccgcgt gggttggcca
     5881 acaggatctg catgtttatg cctccagcgc cggatcgatt tccagcactt caatatcaaa
     5941 gtgaacggta tgcccggcca gcggatggtt aaaatcaacg gtaatcgagt cgccgttgat
     6001 ttcgcgaatc acgccaggca tttcgctgcc atccattgcg gtaaaaagca taatcgcccc
     6061 gacttccggt tcgcccgccg ccataaactc acggcgcgag aaatactgga tcaagtccgg
     6121 actggggacg ccaaacgcgg cgtcaggctc cagcgaaaac gctttctttt ccccttcttt
     6181 caaccccaga agctgctgct ccagaccttc ggaaagcgag gtatcgccaa gacggaacag
     6241 ggctggcttg ccgttattgc gggtagattc cgccgttgag ccatcatcca gtttcagggt
     6301 gaagtgaacg aggatcgcgc tgttgctctg tacggattta gacatgcaaa ttgctcacgt
     6361 gttttgcccg gaggcacaaa gaacgataaa accgtaggcc ggataaggcg ttttcaccgc
     6421 catccggcac cacgtttgcc tgatggcgct gcgcttatca ggcctacaaa accggataag
     6481 cgcaacccgg tatttacgct tatgcctgct ctttcgctgt cggcttcggc aaaaagcctt
     6541 ccagtactat cagcgcagca ccgatacaaa ttgccgtatc ggcaaggttg aacgtcgcga
     6601 aatgccagtc gccgacgtaa aaatcgatca tatcgacaac gaagccgtgc cacagacgat
     6661 cgaacaaatt acccagcgcg ccgccaataa tgagcgcata agcgatgtta ttcagcttct
     6721 gcgtcgcttt cgagcgatac atcatcacca aaagaattac gcagatccct atcgcaatcc
     6781 cggcaaagaa ccagcgctgc cagctgccgc tatccgccag gaagctaaaa gccgcgccgt
     6841 agttacgcgc ataatgcaga ttaagcgacg ggaacagccc taccgtatcc cccagagcga
     6901 aattctggag gatcaggtat ttgctgccca aatcgataat cagcacgact actaccagcc
     6961 atagccagcg tagtcctgtt gaacagagtg gtttactcat caggcaaatt tacgttgttc
     7021 gccattaccg gcgatgttgc tgacacagcg tccgcagata tctgcatgtt ccgccacctt
     7081 gccgacatca gtagtgtagt gccagcagcg cggacactta tcaccctcgg cacgcgttac
     7141 cactgcctga actgtcgtat taccagcatt gtactgaata ttttcatcat caataccccc
     7201 cgcttgctca gaaatcacga actgggaagt aatgaagata aatctgacct cttcgcccaa
     7261 cagtttcagc ttcttgatcg taccgttagc atcgtcagca tatttcagcg tcacttttgc
     7321 ttccaggttc gatttgatgc cattggcctt ctgattttcc agctctttgt tgacctggtc
     7381 cttgatatag cggacatcgt cccagaatgc gtcattaaat tcttcattct cttccaggcc
     7441 aaacaacccg tcgtaccatt cgccggtgaa gacatatttt tcacgctcgc ccggcaggta
     7501 gccccagatt tcatcagccg tgaaggacat gatcggcgcc atccagcgaa ccagcgcctc
     7561 tgcgatatga tacagcgcag tctggcagct acgacgcgcg acgctatcgg ccttcgcggt
     7621 gtactggcgg tctttgatga tgtcgaggta gaacgacccc atttcaacgg agcagaagcg
     7681 catcaggcgc tgtaccactt catggaagtc gtaagcttcg tatgccttca gaatctcttg
     7741 ctgcgccgtt ttcgcgcagc ccaccgccca cctgtccagc accaccatct cttccggttt
     7801 gaccatatcg gtggccggat tgaagccatt gaggttcgcc agcaggaagc gcgcggtatt
     7861 acggatacga cgatagctgt cagcagcacg tttcaggatt tcgtcagaga ccgccatttc
     7921 gccggtatag tcagtagacg ccacccacag acgcaggata tccgcgccca gtttattcat
     7981 cacatcctgc ggcgacacgg tgttaccgat ggacttggac atcttgcgcc cctgaccatc
     8041 gacggtgaag ccgtgagtca gtacctggcg gtatggcgct ttgcctttca tcgccacgct
     8101 aatcatcagg gaggacataa accagccgcg atgctggtca gacccttcca gatacatatc
     8161 ggcagcgtga ccggcgaatt ccggacgggc gtcaaccacg gagtaactgg tggaaccgga
     8221 atcaaaccaa acgtccaacg tatccggaac tttctcatat tgatcagcat cttcgccgag
     8281 gatctctttc gggtcgagat cccaccacgc ctggataccg tcaacttcaa cgcgtttcgc
     8341 cacctcttcc atcgccgcca gagtacgctc aatcggcagc agctcctgcg tttctttatg
     8401 cacgaacagc gacatcggta cgccccaggt acgctgacgg gagatacacc agtcaggacg
     8461 gttagcgacc attgattcaa tacgcgcctg accccagtcc gggatccact gaacgccttt
     8521 gatctctttc agcgactgtt gacgaagccc ttctttatcc atgctgacga accactgcgg
     8581 ggtcgcgcgg aaaatgatcg gcgttttgtg acgccaacag cacggatagc tgtgctgcat
     8641 tttttcgaca tgcagtagcg cgcctttttc tttcagcagt tcaataacga tatcgttcgc
     8701 tttgaagacg ttaacaccgt caagcgttgg atatgtgcct ggcaggtaag cgccgtccgg
     8761 cccaaccggg ttagccgttt ccagaccgta tttctgacca atcacatagt cgtccgggcc
     8821 atggccaggt gcggtgtgaa cggcaccggt accagcatcc agggtgacgt gatcgccgag
     8881 gatcgccggc acgtcaaagc ccataaacgg atgggtaaag cgcagcagtt ccagctccgc
     8941 gcctttgacg gtgccgagaa tggtgtattc agccgcgcca atacgctgta tgacgctttc
     9001 aaccagatct ttcgccagaa tcaccgcctg accgtcgatc tgcaccagcg cataatcaaa
     9061 gtccggcgcc agggagatgg cgcggttagc cggcagcgtc cacggcgtgg tggtccagat
     9121 aaccagcgac acagggccgc tcacgcccgg caaaccaaac ttcgctttca ccgcatcctg
     9181 atcgacggca cggaacgcca cgtcgataga cggcgacgtt ttgtcgtaat attcaacttc
     9241 cgcttccgcc agcgcggaac gacagtcaac acaccagtgc accggcttag cgcctttgtg
     9301 cagatgaccg tttttgataa ttctgcccag cgcgcggatg atgttggctt cggttttgaa
     9361 gtccatggtc aggtacggat gcgaccagtc gcccaacacg cccagacgaa tgaagtcttt
     9421 acgctggccg tcaacctgag tggcggcata ttcgcggcac ttggcgcgga attcagcggc
     9481 ggtgaatttc tcgcccggct taccgaactc ctgctcgact ttcagctcga taggcagacc
     9541 gtgacagtcc cagcccggca cgtaaggcga gtcaaatccc gacagtcctt tggacttcac
     9601 gataatgtct ttcagaatct tgttaactga gtgaccaata tgaatgctgc cattcgcata
     9661 tggagggcca tcatgcagaa tgaaggtttt tttgcctttt ttggccgcac gaatgatgcc
     9721 gtacagatca tcatcggtcc aacgcgccag cattcccggt tcacgcttgg cgaggtcgcc
     9781 gcgcatcggg aaccctgttt ccggcaaatt cagggtcgat ttatagtcac tcatcagatt
     9841 ctcggttccg tatttcggtt tgataaacac cgtcagggtt acacctgccc ggctagccca
     9901 aaaaacttgc gggccgttaa ctcatcgcgt gcgatttgcg cttttagctc atcaagcgac
     9961 gcaaatcgct gctcattacg tatcttttta cgcagtatta catctatatg gcgaccgtag
    10021 aggtccatta caacgtccag cagatgcact tccagttgtt gacgcacgcc agccaccgtt
    10081 ggacgagtgc caatgttcgc tacgccgggt aacggcttat cgccaagccc ggtgacttcc
    10141 accgcataga ccccttttac cggtgagacc tgacggcgca gcggtaagtt cgccgtcggg
    10201 aagccaatgg tacgtcccag ctcgtcgcca tgaacgacac gcccggaaat agtaaaggga
    10261 tgtcccagca gactttcggc aagcgccagg ttatcttccg ccagcgcctg tctcactgcg
    10321 gtactactga tacgcacgcc gccttcacaa aaggtttggg tgctggaaac cgcaaaacca
    10381 tactccgccc ccgccttctg taataacaag aaatcgcccg cgcggctagc accaaagcgg
    10441 aaatcatcgc cgacggcaag aaattgcacg ccaagtcgct ccaccagcag ttcgctgata
    10501 aacgtttgcg ccgtcaaagc ggcaaagcgg cgatcgaatt tcacgcatag cacatagtcc
    10561 acgccgcact gcgccaggta atgcagtttt tcacgcaggc gcgtcaggcg ggcgggcgct
    10621 ttatccgttg cgaacagctc cagcggctgc ggttcgaaaa tcatgaccac caccggcaga
    10681 ccgcgtctgc gtccttcttc ctgcaaaccc tgcagtagag cgcgatgccc ccgatgtacg
    10741 ccgtcgaaat taccaatggt cagcacacac ccatgcgggg cctgactgag attatgtatg
    10801 ccgcgtatca gcttcatgtc tgactcaaaa cagtgaaaat cgcaagagta taccttgtac
    10861 agcggttaag gttaaccggc gattgccctg atgaaacata aagaagatgc ttttcatcgc
    10921 catgcggcaa actccgcccc aaaacccgcc gcttaatgca atttttctca tggaaaggct
    10981 gtattcacag cacgcaagct ggtagaatcc tgcgccatca ctacgcaacg agtgctgcaa
    11041 tttaaacggc gcttatttgc acaaatccat tgacaaaaga aggctaaaag ggcatattcc
    11101 tcggcctttg aattgtccat atagaacaca tttgggagtt ggaccttggc taatatcaaa
    11161 tcagctaaga agcgcgccgt tcagtctgaa aaggctcgta agcacaacgc aagccgtcgc
    11221 tctatgatgc gtactttcat caagaaagta tacgcagcta tcgaagctgg cgacaaagct
    11281 gctgcactga aagcatttaa cgaaatgcaa ccgatcgtgg accgtcaggc tgctaaaggt
    11341 ctgatccaca aaaacaaagc tgcacgtcat aaagctaacc tgactgcaca gatcaacaaa
    11401 ctggcttaat cgcctgcttg ttatcagctt tgtagaaaaa cccgcgtaaa gcgggttttt
    11461 ttatgcctgc tatctgccgt ttttctcgtc aaccgctggc gctgacctca ctcgttcacg
    11521 ctcttcctgt gccagcctat tttttcagct atccctccct tagtcacgta atacttgaaa
    11581 gttattttct ttcactgttt tccttttctt atttcattac tgaaaaaact gtgaccacct
    11641 tagcaaataa aaacatcgct catttaaaaa ctaataaacg caatcctgat gtaagattta
    11701 ataattgatt gatgccgtcg ggttaactac ttttcatgta caccttactt actcatttta
    11761 atctgaggtt aaattcagaa acgacataaa aataatattc aaaacttgct tagaaagtag
    11821 aggttgtttt tctgggcgta tcgtaccaat atcggagtta tcattatgag ttctgtcatt
    11881 gaggataccc agccttccgg gtcagcatca ttgtctttac tacagcgtat tagctacggc
    11941 tctttggatg tggcgggtaa tctgctatac tgcttcggtt caacgtacat tttatatttc
    12001 tatacagacg ttgcgggcat tagccttgcc gtagcaggca ttatcctgct gctggcgcgt
    12061 attgtcgatg gcatagacgc ccctatatgg gggatcatca tcgataaaac gcgttcacgc
    12121 tacggtaaat gtcgtccctg gtttttatgg ttaccgctgc cttttgcggt attcagcgcg
    12181 ctgtcatttt ggtctcctga tatcagtata acaggaaaag ccatctatgc agcaatatct
    12241 tatatgattg ccagcattct atttaccgga cttaatacac cactcagtgc aatattaccc
    12301 ctgatgacct tatctcccaa ggaaagactg gttttaaatt cctggcgaat gaccggtggg
    12361 caaattgggg ttttattaat gaacgcgacc gccttgccgt tagtcgcttt tttaggtaac
    12421 ggtgatgatc acgctggttt tatttatacg gcgattacat ttgccattat atcttgcgcg
    12481 ctaacgctct ttgcgtttaa aaacattcgt gaaatggatg cggataaaat acagcatgaa
    12541 cctaagttgc cgatgaaaaa aagtttcgcg gcgatgaaag gtaactggcc atggattctg
    12601 atggtgctgg ctaatctgat cttctggatt gccctacagc agcgctccac gaccattgtc
    12661 tattatctga cctacaacct cgaccgtaaa gatctggtgc cgctgattaa cagcctggcg
    12721 acgattcaga tcctgtttat catcgctatc cccttcttta gcaaatacct ggctaaaacc
    12781 tggatatggg taggcggtct gctggtcgcc acgtttggcg gcgtcatgat gtggctggca
    12841 gcggacaaca ttactttcct catcgccgcc tggatactcg gcaatatcgg cagcggtatc
    12901 gcctgctcaa tgccatttgc catgctgggc ttcgccgttg atttcggcgc ctggaagacc
    12961 ggtattaagg ctaccggcat tcttatcgcc ttcggcagta ccttctgcat caagatgggt
    13021 agtggcctcg gtactgcttt agccgcctgg atcatgaaca gttttggcta tgtccccaac
    13081 catgcccaga gtgctgcggg tctggaggga attacctggg cctttatctg ggcacccgcc
    13141 ctactcttcg cgctcgcagc gatcccatta cttttctttc gcaaatacga agcgatggaa
    13201 gagaagattc gccacgatct ggaaaccatc aactcataac gttctttacc ttcaccctcg
    13261 aatataggag gcaccaccat gccatttatg caacaagacc cacgtcgtct ggtctggcag
    13321 caaaacgatc gctatttatg gattgaaccc tggggcgaga acagcctgcg cgtacgcagt
    13381 ggccgtcatc tgccggtaat gagaaatgaa gactgggcat tgactgagcc agtcgcagaa
    13441 agccagtgcc acattgatta tgagcaccac caagcaacgc tgaccaacgg caaaattatc
    13501 gctatcgtca atcaaaaagg acaagttacc ttttaccgcc atccacacaa acccctgttg
    13561 caggagtttt ggcgcctgcg gggcgaaatt ggcgaggatg aatcatctca cggccagtac
    13621 gtcagcgcac tcaaccttga gggacgcgag ttccgcccga ttcagggtgg gaaatattca
    13681 ctgaaagccc gcttcgaagc caccgaaggg gaaaaaattt atggcatggg gcagtatcaa
    13741 caggccaacc tggatctcaa aggatgcgtg cttgagctgg cgcaacgtaa ctcccaggcc
    13801 tcagtaccat ttatgctctc cagtctgggc tacggatttt tatggaacaa cccggcagtc
    13861 ggacgcgtaa cctttgccca aaacgttacc gaatgggaag cgcaggtcag cgaacagtta
    13921 gactactgga tcacggctgg cgataccccg gcagaaattg gccgggctta cgcgctggct
    13981 accggcacgc cgccgatgat gccggactac gccatgggct tctggcagtg caaactccgt
    14041 tatcgtacgc aggaagagct gctggaggtc gcccgcgaat ataagcgccg caatctacct
    14101 atctcggtga tcgttatcga cttctttcac tggccgaatc agggtgactg gatgttcgat
    14161 gcgcgcgact ggcccgatcc tgatgccatg attgccgagc tgaaatcgct gggaattgag
    14221 ctgatggtct ccgtctggcc gacggtggat aaccgcaccg aaagctatcg ggagatgcgt
    14281 gaaaacggct ggctggtaca aacggaacgt ggcttgccga tcaatatgga tttcctcggc
    14341 aataccactt actttgatgc gactcatccg ggcgcgcgcg actatgtctg gggcaaagcc
    14401 aaacgcaact atcacgataa aggcgtgaag ctattctggt tagatgaagc cgaacctgag
    14461 ttcagcgttt acgactacga caactatcgc taccatgccg gaccggtact ggaagtgggc
    14521 aatatctacc cacgcatgta cgctaaaacc ttttttgatg gcatgaaagc cgatggcgaa
    14581 gaccaggtta tcaacctgct acgctgcgcc tgggccggca gtcagaagta cggcgctctg
    14641 gtctggtcag gggatattca ctcctcgttt agatcgctgc gcaaccagtt tgccgccgga
    14701 ctcaatatgg gaatagcagg gataccgtgg tggacgacgg atatcggcgg tttccatggc
    14761 ggtaatattc acgacccgaa attccatgaa ttgctgattc gctggttcca gtggggcgtc
    14821 tttagtccgg tgatgcgtct gcacggcaac cgcgatccgc aaattttacc cgcgcaaccg
    14881 tatcgggatg gtatcgccca gtgccctaca ggtgcgccga acgaggtctg gagctacggt
    14941 gaggaagtat gcgacgtact gacaggttgc ctagcgttgc gagaaaaact caagccctat
    15001 atcaaagcgc tgatggagga aacccataag cacaatacgc cagtgatgcg ccccctgttc
    15061 tttgaattcc ccgaacagga aacaagttgg acaatcaccg accagtactg ttttggtcct
    15121 gacctgctga tcgcccccgt catgcatgaa ggtatgcgcg aacgtgatgt ctggctacca
    15181 gaaggggaaa catggacgga tcttgcgacc ggtgaaagct attcaggagg gcagacgctg
    15241 cattacgcta cgccactgaa cagaattccg gtgtttatcc gcgaaggtgg gcagtaccgt
    15301 agcctactga acttgtagaa tgattccggc tgcgggttag ttccgcagcc ggaagtatta
    15361 cggtaggtat gtctactgta gcttaaacaa tgccgagtag tccgcattgc aaatacgctg
    15421 caccgccgga tgctggatca ttctctcggc aaaaatcgca tgatattctt ccatgacatt
    15481 ctccacgcgc ccaatctcta ttaccgactc atcggcataa aaatccagcg aataaaggct
    15541 cggcgccaca aaaatcgcat catgcgtcgc gccaaacgcc ttcattaagg ccgcgtcatc
    15601 aaattcaccg aggatctcaa cctgcaaccc ctgcgaatta aaccagttca acaacttacg
    15661 ccccagcatt gagcgacgtc ccggcaccag caaccgtcgc tcttccaggc aggcaggaaa
    15721 cgctttttca ggaagcggat tcgtacacca gaaactgacg ctgcattcgc cgattttgac
    15781 tgagaatagc ccctcctgct gcgtggaatc tatcgggcag tcggagataa tcatatccag
    15841 cttgtgctgg ctgagctgtt cgagcaacat ttcgtgcgtg gactcgaagc aacgcagatg
    15901 tatgggttcg tccaccacca ccgccgcatc cagaacgctg ctgaccagac gcttggataa
    15961 agcatcggcg acgccgacat caaacaacag gtttgattct ttgcggtaat tgacgatatc
    16021 cagcatctcc tggcttagcg taaacatttt gtccgcatag cgaaaaacca gctcgcccag
    16081 ttcgctgggt tcaagaccgc gtcccttacg tttaaatagc ttcccctgta aacgctcttc
    16141 cagggcttta atttgaccag taatggtttg cggcgtcaga aaaagcgcct ctgcggcgcc
    16201 cacgacagaa ccttctttat agacatgcca gaaataataa agatggttgt agttaatatg
    16261 agacatgctc atttctctcc ctgctcaatg tcgtaaggga gcgatacatc gctccccctt
    16321 cccttcgtac tggttatgcc ggcgcgttca aacgcgcgcg caaccagcta taccccacca
    16381 ctgcggagag caatgaacca atcaaaatgc ccaatttcgc ccagttaata agttccggat
    16441 cgatattgcc aaatgccagg ctggcgataa agatggacat cgtaaagcca atgccacaca
    16501 aaatgccgac cgccatgatt tgctgataag tggtcccctg cggcagatgc gccagcttga
    16561 aacgcagcgc cagccagcaa aacaggctaa tccccagcgg cttaccaatc agcagaccag
    16621 caataattcc caacggcagc atggaggtca gaccgtccat cgtgacgccc tgaagagaaa
    16681 cgccggcatt cgcaaaagcg aagagcggca ggatcaggta tgcgacccac gggtgcagaa
    16741 catgctccag acgcttggcc ggcgagcgtc cgtgtttttc tttcagcgga ataaagaagc
    16801 cgacaatgac gcctgccagc gtcgcgtgaa cgccggactt cagtaccgcc gtccacagca
    16861 ctgccccgac cagaatatat acccctgtcc gcctgacgcc gcacaggttc agcagcgcca
    16921 gcacggcaat cgcgaacgcc gccacgccca gcgagacgat agaaagatcg ctggtataaa
    16981 acagtgcgat aataatgatg gcgccgaggt catcgatgat cgccagcgcc atcaggaaaa
    17041 ttttcagcgc cagcggaacc cggctgccta acagcgccag cacgcccagc gcaaaggcga
    17101 tatccgtcgc ggcaggaata gcccagccct cacgagtgac cggatcggag tagttaaagg
    17161 ccagatagag caatgctggt acaatcatcc cgccgatggc ggcaatcacc ggaaaagcgg
    17221 cctggcgcag actggctaac gagccttgca tcagttcgcg cttaacttcc aggccaatca
    17281 acaggaaaaa cacggccatc agcgcatcgt tgatccacaa cagcatgttt ttgttgatct
    17341 caagcgcccc aacccgtagc tgaaccggcg tctccagaaa atcatgatac catccactgg
    17401 tcgcgcccat attggccatc agcatagcca gcgcagcggc gatgatgaga atgatgcccc
    17461 cagaggcatc gctgctaaaa aatcggtgca gatgtttcac tttttattct ctcaatcagg
    17521 tgaattcttc ggatctacta tcttacctcg cctgactcat cgttaaaatt agattatata
    17581 tgatgaatag ctcgtttttt acgaaatgaa gtccgactta cgccggactt ttttagtgca
    17641 gtcagtcatt gatgatagac cgctacgcgt acagatccat tttatacacc cggaaactgg
    17701 taatatcgta gcgatagcct tccccgttcg tttccgcgtt tttgtagtaa cctgacgtca
    17761 tagtcgcttc aaaaagcacg gttttctccg taggcgcaat ctcctgtaaa attagcagcc
    17821 ccatcgcctc gctgcccgcc tgcggatcga taatatcgct ctcgccaggc tggcaagaga
    17881 tggcgcggcc attttcatca aacgtgcagt cggcaaaatg caccacaata ttgccattct
    17941 gctggatcgc tttcgcgcta acgcagctac tgtagccacg cgcgcccagc tccttgccgt
    18001 attcaaatgg ccgcataacg gtcatctcat tcatattcac cacgaaatgg acaatgcggc
    18061 tgtagttatc cggcggtaac aggcttttgc tgtcatcacg cgaacggtag ttaccgttat
    18121 caaataccat aaactccact atacccggcg tattattggc gatttcaacg acgttatgct
    18181 ggccccacgt ccaaaagtca cggtcggccg cgtcgatatc ctcctgtttg ctaaagtcat
    18241 aaagcgccac accttcactg tcgaccgggg ttaaaagata aggctgataa gcgtcgtccc
    18301 agtcttcatg cgttgacaaa ataaagcgta acgcttgcgt ttgcagatcg acgccaaaca
    18361 ccgcgctctg atgacgcccg gacgcaatta acaactgatt cgtctcattc acgtagctct
    18421 ggtttatgtg cagccagtct ttaaccgtcg ggtcttctcc cggcgccgta cctgaaggac
    18481 gggaaacccg cgtcgtatcc aacaccttcg ccatatcgta gtaagccgtc tccagtccgg
    18541 tagccagatc gacaaccgat acgccgtctt cattggtttt caaatcgtcg ggccgacccg
    18601 aggtatattc agagggcgca acaatggtat tactgtccca cggccagata gaatggtgaa
    18661 attggttatc gagattatag aatgtgtgaa gacgccccat catgtcgaac tcatacatat
    18721 ccagataggt atttttcgct tctgaagtgg tgaggaaatg gccattatca attcgaacaa
    18781 aattataaga cggataatcc tgagtaacgt accagcgcac cagaccattc tgatctaatg
    18841 cgtaattata gcgatcgaaa tgcgtaacaa aataaaaccc tggcgccatc ttgtccacat
    18901 cggtagcagg ttgcgtcacg ttgataatcg gaaaacctaa tacgacctcc gcggaatcta
    18961 ccggcggtaa cggctgtgtg gtgagcgtat agacggcaag cggcgtatct gcctgagaaa
    19021 agacaatacg gttttcagtc tccgctacca gccccagaac cggcaacaga tttgcgcctg
    19081 ccgtaagggt gtaaagatgt tctaccggca tcgccgtttt tgccgcatcc tggaccgtga
    19141 ccatgatctc agccggttcc agactccaga cgccggcata ggcgcttaaa ggtgccgtgc
    19201 cgtaagggtc taacaacatg agcgcatttt ctaccgtatt ctcttgcgtg acctgcgcaa
    19261 ggcaattttc ataaatagcg gtatggttaa gcaccatttc attattgata tcgataccct
    19321 gattaatcgc cggacgcggc gcaggaagga caacagacgt tgcagttaac gtattcatga
    19381 taaatctcca gtgtattaat ctcatcgccc ctcatgggga ccacgaaaat taatactctg
    19441 gatttttaag ccgtccgaat aaaataccgc aacaacacct catcacactt tttattttag
    19501 caattcagtt acatgaagcg tcatattcaa attttaggta atccagtacg gcaacaacat
    19561 tgccaggaga catccggtta agatgcggca ggaagggatg gttgtgaaca tagcgaataa
    19621 acgccgtcgc gctatttaac gtcgcatgac gtaacaaact caccttttta tttcctgtga
    19681 gattgcatac tgccatcgca taatcccgtg tggaaaatgt acgccagacg ttgttgcgaa
    19741 ttccgccgct caaaaacaac cgcggaggga gatcgcgttt gggcggcgta acgcctcttt
    19801 cacgcacaaa cgaaatatgg cagcgcccct gacgaagata gctaaaattc gccatcatac
    19861 agccgcccag aataaagcat tcgtgatcga gataatgctg gacattcagg gagcgctcat
    19921 ccgtcaacgc ctgaaccaac tcaaaatgtc gataagcagg taatacgggt tttactaaca
    19981 tccccggatc gtttttatat aaaatggcgg ggccgtaatc cacatcaaat aatacattgc
    20041 ggcgcatggt cagcgcctct tttcgctgca ccagatgcgc cagcgtgccg gacggaagtc
    20101 gttcttcgta atcagaatga tattgataat ccgcttccac cggttgggcg gagtaattcg
    20161 ttgagatcgc aacgacctta ccgctctcct cttccgccgt caccagcaca tataagctgc
    20221 tgtcgccgcc gttaaatttc acacgaaacg cccgcgtgct catagcgata tcaaacgcgg
    20281 gaaacacaaa atcgcgttcc gcttgattag cgcgacggga cagtttttgt aattcgcggc
    20341 taaaacccgt gctgtctatc gccagcgccg cgcgtatttc aactagcgac gctccttcgc
    20401 caatcaacgt ggcaaggttc tcttgtctgg cgtcgctcct gatagcggta taggagatga
    20461 acgttttatt acactggcgg caatacatac gccgttcacc tttagtggaa aatccatatt
    20521 tttcagcgac gtcccgccac aatgcggaca ggacttcacc agacctttcc agggttgatt
    20581 cgccgcctgg cgaaaaagat taagcgatct ggctgagata atggggaaca aaaaaccgca
    20641 cgctcgacag agaacatttt tcccttgcgg tagatagtct gggctcccca gaatccccag
    20701 atttttgcag cctggcgttt tgcaagcatc gacattaatg tgagaaaaca tattcactcc
    20761 ctgcgaatac taccttcaaa caaatattga ctttatttct gcaagtgaga tgcctttttc
    20821 atacagggtt cgcatggcac tcatcgccgt cgcggtatgc gagaaaaaag cctgataacc
    20881 tgcacacaga tagttatgat tggttgcgcc tgacgcagag ggtaaaaaac gatgtttcgg
    20941 acagccgcca tagcaggcga acttccattg acagcgatga cactcctgcg ccattgaacg
    21001 ctgtttatcg ctgccgaact ggcgattttg ttcgccctga ttcatttgac gcagcgtctt
    21061 ctggtggata ttccccagtt taaattgcgg atatacgaag tgatcgcagt tataaacatc
    21121 gccgttcatt tccatcgcaa acgcgctgcc gcaggtggga gcaaaaacgc aaacctgcgg
    21181 cggcaggccg caccaggccg ccagcgtctg ttcaaatagc tggatgccga tatcgccgat
    21241 atcctcacgg atccagatat caaataccgc attcagaaac tgaccaaatt gcaggctatc
    21301 gaccgaccac ggcgtcatcg cgatatgttt atcctgcggc tgcgccagcc cattttcccc
    21361 acagcgttca actaaaggga taaattgcat atagcggcta ccaacgcttt tcaggtagcg
    21421 atagacctga acaggatgat gcatattggt acggttaacc accgtgaggg tattaaattc
    21481 tacgtcgtgc tgcgccagac aacgcaccgc attttctact ttttcatgcg tcggctttcc
    21541 ggagcgcgtc actcgccatt catcgtgtaa cgcggcatcg ccatcaatag agacgccaac
    21601 cagaaaatca tgctcccgga agaaggtcgc ccagtcatcg ttgatcagga tgccgttggt
    21661 ctggaaggta ttgacgatgg ttttgccgcc acaatagcgc tgctgaaatt caacggcttt
    21721 acgataaaac gggatgccca ttaatgtggg ttccccgccc tgccacgcaa aaatgacctc
    21781 atcaatatcc tgtgcggcaa tctgctgcct gatgaagagt tcgagggtct cttccgacat
    21841 tttgtaatgg ttttttcgat ccggatagag cttttctttc tccagataaa aacagtactt
    21901 acagtcaagg ttacacaccg atccggttgg tttaaccatg acctgacaac ttttcccaaa
    21961 catcattacc ttccctgaaa taaaagaacc tgatccggca cagagtgacc ggatcaggtg
    22021 ggcatcgccc taagtggcat acttaatttt ttataattat tccattagcc ccaggtgaca
    22081 ggcgtcggct tatcgccacg ggctttcatc agcgaatcgt tatcaatatc ctttttatac
    22141 ttcaggaact taccgtaaag ctgtttctca atctgcggct gtttaccaat ttgattgagc
    22201 gtctcgaaac gatcggtttt caggttatag agatatttag gtttattctg gcgatcgatg
    22261 atcatcttcc agtcgccgtc gcggatcgcc cactcatccg tcggatcgtc ctggaacggc
    22321 atatcgatac cgaagatcag cggtttctgg cgttttaacg tcttgtcctt caggagcgga
    22381 actaaagact gaccgtcgta ggtacgatcg gtcgggagtt taaagtccat catgttggcc
    22441 agcgtcggca accagtcaag accatatacc ggcgtgtccg ttaccatccc ctgtggaatg
    22501 tgcttgccgt atttgatgat tgccggtacg cgaatgccgc cttcccacag gttgtcttta
    22561 cgcccgcgca gaccgtcggt ttccccggcc agtttcagct cgtatacctt acgcgcttcg
    22621 cgcgtgacag ggccgttgtc gctggtaaag atgacgatgg tgttatcttc ctcgcccatc
    22681 gccttaattt tatccagcac tttaccgacc tgctcatcca tgtagctgat attggcgtaa
    22741 tattcgccgg tgccgcgcca cggtttgtct gcccagtcgc cgtagaacag atccggatgc
    22801 tgcttctggt agtcggtcat gtactgcgaa tacatatcaa ggtatttttt cggcgacgcc
    22861 agcgggctat ggacttcggt aaaggcgaca tataagaaga acggattatc gtctttctta
    22921 ttatccagcc agttcaccac ttcagagctc acaaactcgc cgctcatctt atctgcgcgg
    22981 ccaatatgtt ggccattacg aatccacccc gtaggatgca ccacgccata gcgcgggcgc
    23041 tccttggcgt tatccagcgt agcatcggtg acaaatcccg ccggattaac caacgtatag
    23101 tcaaagccca tgtctttcgc ctgcggctga tcggtgcgat cgccgcccgc attcaggtgt
    23161 aatttcccca tcatcgccgt atcgtagccc tgctgtttta gcagattggc gatagtcagt
    23221 tcattacgcc ccagcgcaac atctttgcct tccggtatcc aggaacggat tccggtacgg
    23281 aacggcatac gaccggttaa caggcccgcg cgggaaggag aacacagagg cgctggcgca
    23341 taatagtcgg taaacttcac cccctcctgc gccaatttgt ctatgttagg tgttttaacg
    23401 atgcggtgcc cgtaggtggc gagatcgcca taccctaaat catccgccag aataatgact
    23461 aagttaggac gctttgcggt tgccgcttgc gcggttgata atacgcatcc agcgcatagc
    23521 gccaacccta tcatactggc aacgactgtt cttttcattt caactccttt gagttatcgc
    23581 acggtctgat tacgatatat ttgccgatag acccggctgc ggaa
//
LOCUS       DAJVKX010000063        23309 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000063 DAJVKX010000000
VERSION     DAJVKX010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23309
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.063"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            202..1479
                     /gene="waaA"
                     /locus_tag="OPY25_002571"
     CDS             202..1479
                     /gene="waaA"
                     /locus_tag="OPY25_002571"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HCS0928161.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRR
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGNDVQ
                     HVYLPYDLPDALNRFLNKIDPKLVLIMETELWPNLIAALHKRHIPLVIANARLSARSA
                     AGYAKLGKFVRTLLRRITLIAAQNEEDGERFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRSQWAPHRPVWIATSTHDGEESIVIAAHQALLHQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSASTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITITDAATLAKEVSSLLTDADYRN
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            1488..1967
                     /gene="coaD"
                     /locus_tag="OPY25_002572"
     CDS             1488..1967
                     /gene="coaD"
                     /locus_tag="OPY25_002572"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCS0928162.1"
                     /translation="MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKP
                     MFTLNERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQL
                     AHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK"
     gene            complement(1995..2804)
                     /gene="mutM"
                     /locus_tag="OPY25_002573"
     CDS             complement(1995..2804)
                     /gene="mutM"
                     /locus_tag="OPY25_002573"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HCS0928163.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRL
                     SDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEALPAEKHDHVDLVMSNGKI
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSTEECDLLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRHCQK"
     gene            complement(2902..3069)
                     /gene="rpmG"
                     /locus_tag="OPY25_002574"
     CDS             complement(2902..3069)
                     /gene="rpmG"
                     /locus_tag="OPY25_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCS0928164.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            complement(3090..3326)
                     /gene="rpmB"
                     /locus_tag="OPY25_002575"
     CDS             complement(3090..3326)
                     /gene="rpmB"
                     /locus_tag="OPY25_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCS0928165.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRIIDKKGIETVLSELRARGEKY"
     gene            complement(3544..4209)
                     /gene="radC"
                     /locus_tag="OPY25_002576"
     CDS             complement(3544..4209)
                     /gene="radC"
                     /locus_tag="OPY25_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCS0928166.1"
                     /translation="MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLA
                     KEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLS
                     PEMTREFLQSQLTGEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIK
                     LNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAER
                     GWI"
     gene            4385..5605
                     /gene="coaBC"
                     /locus_tag="OPY25_002577"
     CDS             4385..5605
                     /gene="coaBC"
                     /locus_tag="OPY25_002577"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HCS0928167.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRERGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVASGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLFIWGPDSGSQACGD
                     VGPGRMLDPLAIVDKAAAHFAAVNDLRHLNIMITAGPTREPLDPVRYISNYSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPMPPFVKRVDVITALDMEAAVQAAVQQQHIFISCAA
                     VADYRAETIASEKIKKQAAQSDELIIKMVKNPDIVAGVAALSDNRPYVVGFAAETNNV
                     EEYARQKRTRKNLDLICANDVSLSNQGFNSDKNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            5583..6041
                     /gene="dut"
                     /locus_tag="OPY25_002578"
     CDS             5583..6041
                     /gene="dut"
                     /locus_tag="OPY25_002578"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCS0928168.1"
                     /translation="MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELA
                     PGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIW
                     NRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK"
     gene            6149..6745
                     /gene="slmA"
                     /locus_tag="OPY25_002579"
     CDS             6149..6745
                     /gene="slmA"
                     /locus_tag="OPY25_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HCS0928169.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTSTRLRLIVLLILGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDKNLLAS
                     QLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(6823..7464)
                     /gene="pyrE"
                     /locus_tag="OPY25_002580"
     CDS             complement(6823..7464)
                     /gene="pyrE"
                     /locus_tag="OPY25_002580"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HCS0928170.1"
                     /translation="MKPYQRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDKDLPYCFNRKEA
                     KDHGEGGSLVGSALQGRVMLVDDVITAGTAIRESMEIIQAHRATLAGVLISLDRQERG
                     RGEISAIQEVERDYGCKVISIITLKDLIAYLEEKPDMAEHLAAVRAYREEFGV"
     gene            complement(7543..8259)
                     /gene="rph"
                     /locus_tag="OPY25_002581"
     CDS             complement(7543..8259)
                     /gene="rph"
                     /locus_tag="OPY25_002581"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCS0928171.1"
                     /translation="MRPAGRSANQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRATHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKTLGEFTITLDCDVIQADGGTRTASITGACVALADALNKLVANGKLKTNPMKGMVA
                     AVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFSHEELLTLL
                     ALARGGIESIVATQKAALEN"
     gene            8385..9248
                     /locus_tag="OPY25_002582"
     CDS             8385..9248
                     /locus_tag="OPY25_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCS0928172.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRTRLTRGKVECMLRFEPDASAQGELILNEKLAKQLVSAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
                     EGVSAEVAKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVMMAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINADVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            complement(9298..10200)
                     /locus_tag="OPY25_002583"
     CDS             complement(9298..10200)
                     /locus_tag="OPY25_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0928173.1"
                     /translation="MNLLQMDMNLLKVLYVLLETSSTGKTAQKLALSPSAVSHALMRL
                     RDALNDPLFRREGNRQIATPYAQALRDKLAPVFVSLNEELFGDKENGSRCFRVVLPPA
                     LNALLTPVLAEKGHLHQAVIECLPFARRPWRDELLDSSVDLVLAIGDHQKQVSALHYE
                     RVGTTRLIAVYGAPLRSRLENAAALNFADLQHYQHIYCLPWTKENNELDRQQARAGFE
                     RPLAFVCHDYSQLAPAVQSAPLMAIVPRPWYENLSDKRGLFVLPLAGEQAEGAIFMQY
                     RASTVEWKRRLIDAIRRKLKTYYR"
     gene            10274..11158
                     /locus_tag="OPY25_002584"
     CDS             10274..11158
                     /locus_tag="OPY25_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HARLDQ motif MBL-fold protein"
                     /protein_id="HCS0928174.1"
                     /translation="MNRYVLFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKP
                     MKPFQITEGVWYVGTENLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRLTDVR
                     YLLSSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGRQDFALGDALPFPLVTTD
                     KIIHNQESISLGGVTVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNK
                     NYPDLVTDIQSSFKTLAAQHVDIFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQY
                     VERSRQRFITQLTAQQPQ"
     gene            11406..12023
                     /locus_tag="OPY25_002585"
     CDS             11406..12023
                     /locus_tag="OPY25_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HCS0928175.1"
                     /translation="MLLHVLYLIGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKLFLVLDALGLVVFSI
                     IGAQIALDMGEGPIIAVVAAATTGVFGGVLRDMFCKRIPLVFQKELYAGISFASAVLY
                     IALQHYVMNPDVVVISTLLFGFTARLLALRLKLGLPVFYYRHEGH"
     gene            complement(12020..13704)
                     /gene="ligB"
                     /locus_tag="OPY25_002586"
                     /pseudo
     CDS             complement(12020..13704)
                     /gene="ligB"
                     /locus_tag="OPY25_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462639.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
     gene            13961..14584
                     /gene="gmk"
                     /locus_tag="OPY25_002587"
     CDS             13961..14584
                     /gene="gmk"
                     /locus_tag="OPY25_002587"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCS0928176.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAP
                     RPGEVHGEHYFFVNHDEFKTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLD
                     IDWQGAQQIREKMPQARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALSDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            14639..14914
                     /gene="rpoZ"
                     /locus_tag="OPY25_002588"
     CDS             14639..14914
                     /gene="rpoZ"
                     /locus_tag="OPY25_002588"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCS0928177.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            14933..17044
                     /gene="spoT"
                     /locus_tag="OPY25_002589"
     CDS             14933..17044
                     /gene="spoT"
                     /locus_tag="OPY25_002589"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HCS0928178.1"
                     /translation="MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVRAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVHDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLSSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLAEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQQGEAVVPTVAQSNHGHLPIKGADG
                     VLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETEQ
                     EFITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSTFIRLTARDRVHL
                     ANIMRKIRVMPDVIKVTRNRN"
     gene            17049..17738
                     /gene="trmH"
                     /locus_tag="OPY25_002590"
     CDS             17049..17738
                     /gene="trmH"
                     /locus_tag="OPY25_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HCS0928179.1"
                     /translation="MNPKRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAIWPGSRMRTMASAAAGSNSWVQVKTHRTIDDAVAHLKGRGMQILATHLSDKA
                     VDFREIDYTRPTCILMGQEKTGITQEALDLADRDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEDEQQRLLFEGGYPVLAKVAKRKGLPYPRVNQQGEIDAD
                     ADWWATMQAAG"
     gene            17744..19825
                     /gene="recG"
                     /locus_tag="OPY25_002591"
     CDS             17744..19825
                     /gene="recG"
                     /locus_tag="OPY25_002591"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCS0928180.1"
                     /translation="MSGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGIYATVEGEVLNCNITFGGRRMMTCQISDGSGILTMRFFNFNAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALELLDTCAIAELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKH
                     PAQRRLILEELLAHNLSMLALRAGAQRYHTQPLSTNNILKDKLLASLPFKPTSAQARV
                     VAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFEPLGVEVGWLAGKQKGKARQAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRHEIIDRVRNACTTEGRQAYWVCTLIEESDLLEAQAAEATW
                     EELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRIARHIHERYPQQAQALIER
                     WMPETERYSNA"
     gene            complement(19861..21066)
                     /gene="gltS"
                     /locus_tag="OPY25_002592"
     CDS             complement(19861..21066)
                     /gene="gltS"
                     /locus_tag="OPY25_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016507315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HCS0928181.1"
                     /translation="MFELDTLSTLVAATLVLLLGRKLVQSVSLLKKYTIPEPVAGGLL
                     VAVALLVLKKSVGWEVNFDMTLRDPLMLAFFATIGLNANLASLRKGGRVVGVFLVVVV
                     GLLLMQNAIGIGMASLLGLDPLMGLIAGSITLSGGHGTGAAWSKLFVERYGFASATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPDGMPDDQAVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTVLELPVFVCVLFVGVILSNGLALVGFYRVFERAVS
                     VLGNVSLSLFLAMALMSLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITDRFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAQ"
     gene            21293..22684
                     /gene="xanP"
                     /locus_tag="OPY25_002593"
     CDS             21293..22684
                     /gene="xanP"
                     /locus_tag="OPY25_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HCS0928182.1"
                     /translation="MSVNAIEPADAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVLSRILHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLAIIILLNRQRNP
                     YLRVASLVIAMAAGYLLAWFMGMLPENNAPVSQDILMVPTPLYYGLGIDWNLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPQILQFAPEWVKNLLSSGIAAGGIT
                     AIVLNLILPPEKP"
     gene            22805..>23309
                     /locus_tag="OPY25_002594"
     CDS             22805..>23309
                     /locus_tag="OPY25_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HCS0928183.1"
                     /translation="MKLIGRLLLYVLIACLVVIFGFYFLLQTRWGADHVSNWVSENSG
                     YHLTFDVMDHRFSAPSHLLLENVTFGRDGQPATLVAKTVDIGLSIRQLTAPLHVDTIL
                     LQDGTLNISVQTAPFPFEADRLQLRNMALNSPGSEWRLSAQRVNGGVMPWRPEAGRVL
                     GNKAQIQL"
BASE COUNT         5445 a         6469 c         6060 g         5335 t
ORIGIN      
        1 tcttgtgaat ggtcattccc attgtctggg gcgacaaggg cggcaaattt caatggattg
       61 cgtaaaaatg caaaaataat ggggttcagc gcctggaatc ctcccttctg agccaatttg
      121 gcgcaaaaat gggaaaagta atggtaaagc ccaggctaaa tacatagaat ccccagcaca
      181 tccataagtc agctatttac tatgctcgaa ttgctttaca ccgctcttct ctaccttatt
      241 cagcctctga tctggatacg gctttgggtg cgtggacgta aagcgccggc ctatcgtaag
      301 cgctggggtg aacgctacgg attctaccgc cgtccgttga aaccgggcgg aatcatgctg
      361 cattccgtct cggtgggcga aactctggcg gccatcccat tggtccgcgc tctacgtcat
      421 cgctatcccg atctgcctat taccgtaacg accatgacgc cgaccggctc ggagcgcgtc
      481 cagtccgcct ttggcaacga tgttcagcac gtttacttac cttatgattt gcccgatgcg
      541 ctcaatcgtt tcctcaataa gattgatcct aagctggtat tgatcatgga gactgagctc
      601 tggccaaatc tgattgctgc gctgcacaaa cgtcatattc cgctggttat cgctaatgcg
      661 cggctttccg cccgctccgc cgcgggttat gcgaagcttg gcaagtttgt ccgtacgctc
      721 ctgcgccgta tcaccctgat tgccgcgcaa aacgaagaag atggcgaacg ctttgtggca
      781 ttgggcgcga agaacaatca ggtcacggtc accggcagtc tgaaatttga tatttcagtt
      841 acaccgcaac tggcggctaa agccgttacg ctacgtagcc agtgggcgcc gcaccgtccg
      901 gtctggattg ccaccagcac ccacgatggc gaagagagta tcgttatcgc cgctcaccag
      961 gcgttattac atcaattccc gaatttatta ctgattctgg tgccccgcca tccggagcgt
     1021 ttcccggatg ctatcaatct tgtgcgtcag gcagggttaa gctacatcac tcgctcttcg
     1081 ggcgaagtgc cgtccgccag cacccaggtc gtggtaggcg ataccatggg cgaattaatg
     1141 ttgctctatg gcattgccga tctcgccttt gttggtggtt cgctggttga acgcggcggt
     1201 cacaacccgc tggaagccgc cgctcatgcg attccggtac tgatgggtcc gcataccttt
     1261 aactttaaag atatttgcgc ccgtctggag caggcgagcg ggcttatcac gattaccgat
     1321 gcggctacgc tggcaaaaga agtttcctct ttactgaccg acgctgatta tcgtaatttc
     1381 tacggacgtc acgcagttga agtgctgtat caaaatcagg gcgcgctcca gcgtctgctg
     1441 caactgctgg aaccttatct gccaccgaaa acgcattgag ggctgtcatg caaaaacggg
     1501 cgatttatcc aggcacgttt gatccgatta ctaacggtca tctcgatatt gtgacgcgcg
     1561 caacgcagat gttcgaccat gtcattctgg ccatcgccgc cagccccggc aagaaaccca
     1621 tgttcaccct gaacgaacgt gtggcgctgg cgcaaaaagc gaccgcacac ctgggtaacg
     1681 tagaggtggt gggttttagc gacctgatgg ccaatttcgc ccgcgacaga caggcgaata
     1741 tcctgattcg tggtctgcgc gcggtggcgg attttgaata tgaaatgcag ttggcgcata
     1801 tgaatcgcca tctgatgccg caactggaaa gcgttttcct gatgccgtcc aaagagtggt
     1861 cgtttatttc atcgtcgctg gtcaaagaag tggcgcgcca tcagggcgat gtgacccact
     1921 ttctgcccga caatgtgcat caggcgctaa tggataagtt gaaataagtt tccttccttg
     1981 ccgggcctgg cattttactt ctgacagtga cggcaataga acgtcgcgcg ctgtgcgtgt
     2041 ttcgttgcga ctatcggcgt accgcatacc cgacacggct cgcctttgcg cccgtacacc
     2101 tgcaactcct gggcaaaata gcccggcttc ccatcgcttt gcagaaaatc cttcagcgtt
     2161 gtcccgcctt gttcaataga gcgcagcaaa acggctttaa tcacccgcgc cagcaggtcg
     2221 cactcctctg tcgagagtga cgacgccagg cggtcagggt gaataccagc ggcaaacagc
     2281 gactcgctgg cgtagatatt ccccacgccg accaccagct tgttatccat cagccagggt
     2341 ttaatcgccg tcttcttctt cgcgcatttc tgttgcaaat attcgccatt aaactcatcg
     2401 cttagcggct ccggtcccag atgcgccagt acgttatgtc cttccagctc tttggtccat
     2461 aaccaggcgc caaagcggcg aggatcggta taacgtagaa ttttgccatt gctcatcacc
     2521 aaatcgacat ggtcgtgctt ttccgccggc agcgcttccg acagtatccg caagcttccc
     2581 gacatcccca ggtgaataat tatccagccg tcaggcaact ccagcagtag atatttagca
     2641 cgacgctgaa cgctaaggac gggtgtgtcg ctcagacgat aaatttcgtc tgaaaccggc
     2701 cagcgcagac gaccgttacg gatatgggcg tgcaggatag tagcgccaac taaatgaggt
     2761 tcaatacccc ggcggctggt ttcaacttcg ggtaattcag gcataacgtc tccggctgtg
     2821 tggcaggtct cattaatatg gggacggcca gaaaacaaaa aaccccgccg aagcgaggtt
     2881 tttgttacat caaagcgaga attatttgat tttcgcttct ttgtagatca cgtgctgacg
     2941 gacaactgga tcgaattttt tcagttccag tttttccggc ttagtacgtt tgttcttcgt
     3001 agtggtatag aagtgaccag taccagcaga agaaaccagc ttgattttct cacgaatacc
     3061 tttagccatg atttatttcc tcttagtact tagtactttt cgccacgggc acgcagttca
     3121 gacagaactg tttcgatgcc ttttttatcg atgatacgca tacctttagc agatacacgc
     3181 agggtgacaa aacgcttctc gctctcaacc cagaaacggt gagagtgcag gttaggcagg
     3241 aaacggcgtt tagtcgcgtt cagtgcgtgg gaacggttgt taccggtcac cggacgcttg
     3301 ccagtaactt ggcagactcg ggacatgtct attctccaaa aatcaaatta gctcgagctt
     3361 cgtatggggt atcggcgcct cgtcaggctt tacagcctgg tcatcgcgca gttctattga
     3421 actctcgatt gccaggccca aatgccaaac ccgagattct caaaggtggc gtagtatacg
     3481 ctgacccggc gatatgctca agtcccgaac agacaaagat cccgatggat cgcgcaaaga
     3541 atcttaaatc cagccgcgtt cggcaaaaga aacgtactct ccgcgcccaa ttatcaggtg
     3601 atcgagcacc cggatatcca taaactggca acactttatc acgcgctcag tgataagttt
     3661 atctgcttta cttggctctg cgcagcctga agggtgatta tgcgccagaa tgaccgctga
     3721 agcattgagt ttaatcgctt cccgaacaat ctcacgcgga tgcacctcta cgtggttaag
     3781 cgtgccggaa aacaggcggc tgtgctgaag cacccggtgc tgggcatcta ggaagatcac
     3841 cagaaagatc tcacgctctt cgcccgtcag ttggctttgc agaaattccc gcgtcatttc
     3901 cggactcagc aacgcacttt cctcattcat gcgcacgctg taatagcgcc ttgccagctc
     3961 agcaatgcct ttcaactgcg cgaatttcgc caggccgatg ccgtttacgc cgcgaaactg
     4021 cgcaaagtcc gccgacagca ggccatacag cgacccaaag tgctgcaata tctcttttgc
     4081 caacgtcata acatcttttc ccggcgtgcc ggtacgtaaa aaaagcgcca gcagttccac
     4141 gtcgctgagg gaagcaatgc cggatctgag cattttttca cgcggcaata attcgtccaa
     4201 cgtatccata cgcgcacctc cttttttaag gaagcggcat agtggcacag cctttgggag
     4261 agatcgacgc cccgattttg ttcttgcgta gcgcctcgca aagtggagcg caggcaaaga
     4321 cacgacgccg tagagattgt gataaaatag ccgcctttca aagtcaccca acaggaaaga
     4381 catgatgagc ctggccggta aaaaaattgt tctcggcgtt agcggcggta tcgctgcgta
     4441 taaaacgccg gagctggtgc gccgtttacg tgagcgcggc gctgacgtgc gcgtggcaat
     4501 gaccgaggcg gcaaaagcct ttattacccc cctgagctta caggccgtgt cgggctatcc
     4561 cgtatccgac agtctgcttg accctgccgc cgaagctgcg atggggcata tcgagttggg
     4621 gaaatgggcc gacctggtga ttcttgcccc cgcgaccgcc gatctgatcg cccgtgtagc
     4681 atcgggtatg gctaatgatt tagtctccac catctgcctg gcgacgccag ccccggtggc
     4741 cgttcttccg gccatgaacc aacagatgta ccgcgctgcc gccacgcaac ataatctgga
     4801 ggtgctcgcc tctcgcggcc tgttcatttg ggggccggat agcggcagtc aggcgtgcgg
     4861 cgatgtaggc ccaggccgaa tgctggaccc attagctatc gttgataagg ccgccgcgca
     4921 tttcgctgcc gtcaacgatc tgcgacatct taatatcatg attacggcag gcccgacgcg
     4981 cgaaccgctc gacccggtgc gttatatttc caactacagc tccggtaaaa tgggcttcgc
     5041 tattgcggcg gccgcagcgc gtcgcggcgc aaatgtcacg ctggtctccg gtcccgtttc
     5101 gttaccgatg ccgccttttg taaaacgggt tgatgtcata accgcgctgg acatggaagc
     5161 cgctgttcag gccgccgttc aacagcagca tattttcatt agctgcgccg ccgtggctga
     5221 ctatcgcgca gagactattg ccagtgaaaa aatcaaaaaa caggcggcgc aaagtgatga
     5281 attaataata aaaatggtca aaaacccgga cattgtcgcc ggggtggccg cactcagtga
     5341 caatcgcccc tacgttgttg ggtttgccgc ggaaacgaat aatgtggaag aatacgcccg
     5401 gcaaaaacgt acccgtaaga accttgacct gatttgtgca aatgatgttt ctctttcaaa
     5461 tcagggattt aatagcgata aaaacgcttt acaccttttc tggcaggatg gagataaagt
     5521 cttaccgctt gagcgaaaag aactcctggg ccaattatta ctcgacgaga tcgtgacccg
     5581 ttatgatgaa aaaaatcgac gttaagattc tggacccgcg tgttggtcag cagtttccgc
     5641 tgccgactta tgctacttct ggttctgccg ggcttgacct gcgcgcctgt ctcgacgacg
     5701 ccgtagaact ggcgcctggc gcaacgacgt tggtgcctac cggactggcc attcatatcg
     5761 ccgatccatc attggcggca gtcatgttgc cgcgttctgg cctgggccat aaacatggta
     5821 tcgtgctggg caacctggtc gggctgattg attccgatta tcaggggcaa ctgatggttt
     5881 cgatctggaa ccgtggtcag gacagtttta ccattgaacc gggcgaacgt atcgcgcaaa
     5941 tggtgtttgt tccggtcgtt caggccgaat ttaatctggt ggaagcattt gacgccaccg
     6001 aacgtggcga gggcggcttc ggtcattctg gccgtaagta aattttacgc atccccataa
     6061 cgtcataata ctgccgcaag cgctgagttt gcggttatag cgtgggtgct cgcctggcaa
     6121 gtgcttattt tcaggggtat tttgtaacat ggcagaaaaa caaactgcga aaaggaatcg
     6181 tcgcgaagaa atacttcagt cactggcgct gatgcttgaa tccagcgatg gaagccaacg
     6241 catcacgacg gcaaaactgg cggcctcggt cggcgtttcc gaagcggcgc tataccgcca
     6301 ttttcccagc aagacccgca tgttcgatag cctgattgag tttatcgaag atagtctgat
     6361 tacccgtatc aatctgattt taaaagatga aaaagacacc agcacgcgtt tgcgcctgat
     6421 tgtgttactg attctgggtt ttggcgaacg caaccctggc ctgacgcgca ttcttaccgg
     6481 gcatgcgctg atgtttgaac aggatcgcct gcaggggcgc attaatcagc tttttgaacg
     6541 catcgaagcg cagctccgcc aggtgctacg agaaaaaaga atgcgtgaag gcgaaggcta
     6601 cacgacggat aaaaatctgc tggcaagcca gctgttagcc ttctgtgaag gtatgctttc
     6661 acggttcgtg cgtagcgaat ttaaataccg cccaacggac gatttcgacg cccgctggcc
     6721 gctcattgcc gcgcagttgc agtaacgctg actggatagt ggctcacgcc ttatccaggc
     6781 gacagaaata taggcccggt aaagcgccac cgggcaattc gcttacacgc caaattcttc
     6841 ccggtatgct cgcacagccg ccagatgctc agccatatca ggtttttctt ccagataggc
     6901 aatcaggtct ttcagcgtaa tgatggagat aaccttacaa ccatagtcgc gctccacttc
     6961 ctgaatcgcg gaaatctcgc cgcggccacg ttcctgacga tccagcgaaa tcagtacgcc
     7021 agccagtgta gccctgtgcg cctgaataat ctccatcgac tcgcgaatcg ccgtacctgc
     7081 ggtaatcacg tcatccacca gcatcacgcg gccctgtagc gcgctgccca ccagactccc
     7141 gccttcgcca tgatcttttg cctctttgcg gttaaagcag tacggcaggt ctttatcgtg
     7201 atgttccgcc agcgcaaccg ccgtcgtcgt cgcgatcgga atacctttgt acgcggggcc
     7261 aaacagcaga tcaaattcaa taccggaatc caccagcgct tcggcataaa aacggcctaa
     7321 caacgccagg tcgcgcccgg tattaaacag cccggcgttg aagaaatagg ggcttttgcg
     7381 cccggatttc agcgtaaact cgccaaactt tagtacctgc ttgttaagcg caaactcaat
     7441 aaactggcgc tgatacggtt tcatggattc gctccttttc ttactttcat catttacgaa
     7501 atttacggac aaaaaaaagg cgacttttca gtcgccttaa aatcaatttt ctaacgccgc
     7561 cttctgcgtc gccacaatgg attcaattcc ccctcgggcc agcgccaaca aagtgagaag
     7621 ttcttcatgg ctgaacggct cgccttccgc ggtaccctga acttcaataa tgcggccgtc
     7681 ttcagtcatc acgacgttca tgtcggtttc tgcggcggaa tcttcaacat attccagatc
     7741 gcagatcgct tcgccgttaa cgatgcctac ggaaaccgcc gccaccatgc ctttcatcgg
     7801 attggttttc agcttaccgt tggcaaccaa tttattcagc gcatccgcca acgccacgca
     7861 ggcaccggta atagacgctg tacgcgtacc gccatctgcc tggattacat cgcagtccag
     7921 cgtaatggta aattcgccga gcgttttcag atcgaccgcc gcacgcagcg cacgcgcgat
     7981 caaacgctga atttccatag tacgaccgcc ctgcttaccc tttgccgctt cgcgcgcatt
     8041 acgggtatgg gtagcgcgag gtaacatgcc atactctgcg gtgatccacc cctggccttg
     8101 tcctttcaga aaacgtggaa cgccttcttc aatggaggca gtgcacaaca ctttggtatc
     8161 tccaaattcg accagtaccg agccttcagc gtgttttgta tagttacggg tcagggttac
     8221 gggacgcacc tgattagcgc tacggcctgc tggacgcata ttgagatctc cggcttaaaa
     8281 cgaatgtggc tgcgcattat acggacttcc gatggttatt cctatcctga caaggcatgg
     8341 atagctataa tcccctcatc tctcctttaa aaacgggaac atctatgatc cgcagtatga
     8401 ccgcctacgc ccggcgtgaa atcaagggtg aatggggtag cgcgacctgg gaaatgcgct
     8461 cggtaaacca gcgttatctg gaaacttact ttcgtctgcc ggaacagttc cgtagtcttg
     8521 aacccgtcgt gcgcgaacgc attcgtacac gcctgacgcg cggcaaagtc gaatgtatgc
     8581 tgcgttttga acccgatgcc agcgcgcaag gcgagcttat tctgaatgaa aagctcgcga
     8641 aacaattagt tagcgccgca aactgggtca aaatgcagag cgacgaaggg gaaatcaatc
     8701 cggttgatat tttgcgctgg ccaggtgtca tggcggcgca agagcaggat ctggacgcga
     8761 ttgccgcaga aattttagcc gcactggacg gtacgctgga tgactttatc gtcgcgcgcg
     8821 aaacggaagg ccaggcgctg aaagcgctga ttgaacaacg tctggaaggc gtcagcgccg
     8881 aagtagcgaa agtccgcgcg catatgccgg aaatcctgca atggcagcgt gaacgcctgg
     8941 tcgcgaagct ggaagatgct caggttcagt tggaaaacaa ccgtctggag caagagctgg
     9001 tgatgatggc gcagcgcatt gatgtggcgg aagagctgga tcgtctcgaa gcgcacgtca
     9061 aagagactta caacattctg aagaaaaaag aggcggtagg tcgccgtctg gacttcatga
     9121 tgcaagaatt taaccgtgag tcgaacaccc tggcctctaa atccatcaac gctgatgtaa
     9181 ctaactccgc tattgaatta aaagtgttga tcgagcaaat gcgcgagcag atccagaata
     9241 ttgaataatt ctggcgctca atatgtcaca gagtccgcct tatgcgggct ctcgcgttta
     9301 tcggtagtac gtttttaatt tccggcgaat agcgtcgata aggcgtcgct tccactctac
     9361 cgtcgaagcc cgatactgca taaaaatagc gccttccgcc tgctccccgg caagcggcag
     9421 gacaaaaaga ccgcgcttat cggataaatt ttcataccag gggcgcggta caatcgccat
     9481 tagcggcgcc gactggacag caggcgcaag ttgactgtaa tcatgacaaa caaacgccaa
     9541 cggacgttca aacccggcac gagcctgctg cctgtccagt tcgttgttct cttttgtcca
     9601 cggcaaacag taaatgtgtt gataatgctg cagatcagca aaattcaacg ctgcggcatt
     9661 ctccagacgt gaacgcaatg gcgcgccata aaccgcgatc aaacgcgtcg tccccacccg
     9721 ctcgtaatgc agagcgctga cctgcttttg atggtcgcca attgccagca ccaaatcaac
     9781 cgagctatcc aacagttcat cacgccaggg tcggcgggca aaaggaaggc actcgatcac
     9841 cgcctgatga agatgacctt tctctgcgag aacgggcgta agcagcgcgt tcaatgcggg
     9901 aggaagtacc acccggaaac aacgggagcc gttctcttta tcgccaaaca gctcctcatt
     9961 aagcgaaaca aacacaggcg ccaacttgtc acgcagcgcc tgcgcataag gcgtagcaat
    10021 ctggcggttc ccctcccgtc gaaacaacgg atcgtttagc gcatcgcgca atctcattag
    10081 cgcatgactc accgcagaag gcgacaaagc cagcttttgc gccgttttcc ccgtagagct
    10141 cgtctccagc agcacataca gtacttttaa caggttcata tccatttgca gcaagttcat
    10201 taaacgtctc tcttattgaa cctgactaaa ttactgccag gtatactgcg ggcgcttcaa
    10261 tcaggagaac attatgaatc gctatgtatt attctttgta tgtatatttt caacatcagc
    10321 acttcctgcc atggcggcat tagatccttc acaaccgtta tcacccgcgc ctccgttatc
    10381 actgtttaaa gcgtgggcta agcctatgaa gccgtttcaa atcacagaag gcgtgtggta
    10441 tgtcggtacg gaaaatctct cttctattct gctgaccact ccggcagggc atattcttat
    10501 tgatgcgggg ctggatgaaa gcgcaccgca aattaaagcg aatattgaag cggcaggatt
    10561 tcgcctcact gacgtgcgct atctgttgag cagccatgcg cggctggatc aagcgggggg
    10621 catggcacgt ttgaaagcgt ggagcggcgc acaattggtc gccagtcaac ccaacgccga
    10681 tcagatggcg aggggtggac gacaggattt tgcgcttggc gatgcgctcc ccttcccgct
    10741 cgtcaccact gataaaatta tccacaacca ggaaagcatc agcctcggag gggtaaccgt
    10801 gacagcacta ttcacgcctg gacatctgcc cggctcaacc tcctggcgcg taacgctccg
    10861 caacggcaag acgctaattt acgcagatag tctcgccaca cctgactatc tgctgattaa
    10921 caacaaaaat taccctgacc tggttactga tattcagagc agctttaaaa cactggccgc
    10981 ccagcatgtt gatatcttta ttgccaacaa aggtgaccgc ttcgggctac tggagaaacg
    11041 acagcaactt cgcaacggcg atacacaggc attctttgat tccaatggct tgcaacagta
    11101 tgtggaacgc tcgcgtcagc gcttcatcac acaacttacc gcacagcagc cacaatgaaa
    11161 tgactcaccg gcggcgcgtc cagggcgccg ttcaggtaat ttatctaagt caaaacagaa
    11221 aaacctcgta tacaataaac cacaaaaatg atgttcaatt tattgatatt tataataaat
    11281 aattattaat cataaattta gaatcattac taaaatttat taatcgtgta atgccttaga
    11341 aaatctcaat cgtgatacag cgcacaaatc gttaatcttc gcccccagta aattaggggg
    11401 aaatcatgct gttgcacgtt ctttatttaa ttggcatcac tgccgaggcc atgacgggcg
    11461 cactcgctgc gggtcgtcgt cgcatggata cattcggcgt aattattatt gctaccgcca
    11521 ccgccattgg tggaggctcg gttcgcgaca ttctgctcgg tcactatccg ctgggttggg
    11581 tgaagcatcc cgaatatgtc attattgtgg cgactgccgc cgtattgacc accattgttg
    11641 ctcccgtcat gccctattta cgcaagcttt tcctggtact tgacgcgctg gggttggtgg
    11701 ttttctctat tattggcgct cagatagccc ttgatatggg cgaagggcca attatcgccg
    11761 tggtagccgc cgccactacc ggcgtctttg gcggcgtgct ccgcgatatg ttctgcaaac
    11821 gcattccact ggtgtttcaa aaagagctgt atgccggcat ttcgttcgcc tcggcggtgc
    11881 tctatattgc gctacaacat tacgtcatga atccggatgt cgtcgttatc tctacgctac
    11941 tgtttggctt tacagcaagg ttattagcgc tacgtcttaa acttggcctg ccggtatttt
    12001 attaccgtca tgaaggacac taagacccaa atccgggaat atgctgagta gccagccatc
    12061 tgctcagcgc gttgatctgc ggattattcc gccagtcgat aactctcccg gcacggcgct
    12121 cgcccgtcgc tggcaattgc cgccagtgtt gctctgttcg cattaataac tgctcccatg
    12181 agcgatcacc gctggcctgt aatgcggcct gcgttaaggg gatatccatc gccatgatcc
    12241 agcgggtaaa tgactgccgg cgcgccaggt taaattgccg ccatatctgc tcgctttttc
    12301 ctttagcaac gcctggcgtg ttggctattt gcgctgacgt cagggcaagc caggagaaga
    12361 tatgctcaaa gcgatgcgtc tgatgcaaag cccgccagct agcttcaccc attccgtcca
    12421 gacccaacgc cgaccgtgac cccagccata ccagcctgga gataaactgt tcctgacacg
    12481 ttgccgacgc gtaaaagcag gtcagcgagt tgaaatggct acctggcggc acaggcttac
    12541 tccgctcacg actccgccag acgacctcat caagccgagg aatgccttgc ccggccagac
    12601 tcaccaggat ctgatcgccc ggcgcaatat cccacgcttc ccaacgcttc acagaaccga
    12661 tattgacccg ctgaacccgc ttatcatcca atataacggg gacaagcgac gctactacgg
    12721 taatcttgcc gcttttcccc accgagaact gaatagcgct cacttgcgcg acctgcgcta
    12781 ctggcggata tttccatgct gccagccagt cgccctgccc gggtcgccag tattgtgacg
    12841 cgggttcttt agccatgcgt atcactacgc catccgtcac aaagggtaat gctgacgtca
    12901 gccatgactg gcgcgcccgc tcgacctcgc tggcatcttt taccgccaga gaatatttct
    12961 tcgtcagact gaatccagcc ttagcaagtt ggcttaatct ttcgggcata tttgccggac
    13021 cgtccggcca cgcccaaata aaaataccca acgaatttag cgcggaggcg ttatcctggc
    13081 gcattaacat tcctgcggct ttcgagcgcg cattcatccc gcccatccgt tgctggatat
    13141 gtccctcgcg ctgtagaaag atttcgccct gcaacaccgc gttagctagc gcgccttgtg
    13201 ttgtctgcgg tatagagggg atcaggcgaa tttttggcgt ccagtcctcg ccttgtagtc
    13261 cgttaccccg gctaatggcc ctggtcagtt taccgttttg ataaaccagc gttaccgcta
    13321 cgccatccac ttttggctgt acccaaagct cgctgcgccc gcgcatccac tgttctacgc
    13381 ctgtcggtcc gcgagtttac gtacgcccgt gtgcgcaaca gggtgcattg ttgtaccgtt
    13441 taacggcggt gaaaccggag tagatgaaac atcctgacca acacagcgtt gccactgaac
    13501 cagccttgcg ctgagttggt cgtacacact atcgtcaacc gcgctaacac cttgtttcca
    13561 gtagatgtca ttccagtcag cgagctgttg ctgtaaacgg gtgatttctt cagcggccct
    13621 tgctggcggc caggccgggc aaagcgcccc actctgcgaa tgccacaata aaattcccca
    13681 cgccatactt ttccataatc tcatcacaac ctcctgcgca cattgcccgg caggtatagc
    13741 gctttagtga ataaaaaccg acaggtaaaa atgcaccatc cgagccgctt tccagatttt
    13801 ttggtgggtt gctgcaacga cgcgataaaa gcggaaaaag ggacgcaaaa tgcaataatc
    13861 tggcgcaaaa agtgtgacaa agactacgtc gcataacggc gatgtgtata ataagcccgt
    13921 atcaaggctc tatttcgata atcacagacg taagatactc atggctcaag gtacgcttta
    13981 tattgtttct gcccccagtg gcgcgggtaa atccagcctg attcaggctt tattaaaaac
    14041 ccaaccgttg tacgacactc aggtttccgt ttcacatacc acgcgcgcgc cgcgtccggg
    14101 tgaagtgcac ggtgagcact atttctttgt aaatcatgat gagtttaaaa ccatgattgg
    14161 cagggaggcg tttctggagc acgcggaagt gtttggcaat tactacggca cttcgcgcga
    14221 aaccattgag caagtgctgg caactggcgt tgatgttttt ctggatatcg actggcaggg
    14281 cgcccagcaa attcgcgaaa agatgccgca agcacgcagc atttttattt tgccgccatc
    14341 aaagatcgaa ttggatcgcc gtttacgcgg ccgcgggcaa gatagcgaag aagtcattgc
    14401 caaacgaatg gcgcaagcgg ttgcagaaat gagccattac gccgaatatg attatcttat
    14461 tgtgaatgac gactttgata ccgcgttaag cgacttgaaa accatcattc gcgctgaacg
    14521 tctgcgtatg agccgccaaa agcagcgtca tgacgcttta atcagcaaat tgttggcaga
    14581 ctgaacccac tttcagtatc atgcccagtc atttcttcac ctgtggagca ttttaagtat
    14641 ggcacgcgta actgttcagg acgctgtaga gaaaattggt aaccgttttg acctggtact
    14701 ggtcgccgcg cgtcgcgctc gtcagatgca ggtaggcgga aaggatccgc tggtaccgga
    14761 agaaaacgat aaaactaccg ttatcgcgct gcgcgaaatc gaagaaggtc tgattaacaa
    14821 ccagatcctc gacgtccgcg agcgccagga acagcaagag caggaagccg ctgaattaca
    14881 agccgttacc gctattgctg aaggtcgtcg ttaatcacaa agcgggtcgc ccttgtatct
    14941 gtttgaaagc ctgaatcaac tgattcaaac ctacctgccg gaagaccaga ttaagcgtct
    15001 tcggcaggcg tatctcgttg cacgtgacgc tcacgagggc cagacacgtt caagcggtga
    15061 accctatatc acgcacccgg tagcggtggc ctgtattctg gccgagatga aactcgacta
    15121 cgaaacgctg atggccgctc tgctgcatga cgtgattgaa gatacccccg ccacctatca
    15181 ggacatggaa cagcttttcg gtaaaagcgt tgccgagctg gtagaggggg tgtcgaaact
    15241 tgataagctc aagttccgcg ataagaaaga ggcgcaggcc gaaaactttc gcaaaatgat
    15301 tatggcgatg gtgcaggata tccgcgtcat cctcattaag cttgctgacc gtacccataa
    15361 catgcgcacg ctgggctcgt tacgcccgga taaacgtcgt cgtattgccc gtgaaaccct
    15421 cgaaatctac agcccgctgg cgcaccgttt aggtattcat catattaaaa ccgagctgga
    15481 agagctgggt tttgaagcgc tgtatcccaa tcgttaccgc gtcattaaag aagtggtaag
    15541 agcggcgcgc ggcaaccgta aagagatgat ccaaaaaatc ctctctgaaa tcgaaggacg
    15601 tttgcaagag gcgggaattc cgtgtcgcgt tagcggtcgc gaaaaacatc tttactcgat
    15661 ctactgcaaa atggtgctca aagagcagcg ttttcactcg atcatggaca tttacgcttt
    15721 ccgcgtgatc gttcatgact ccgatacctg ctatcgcgta ctcggccaga tgcacagtct
    15781 ctataagccg cgtccgggac gcgtgaaaga ctatatcgcc attcccaaag cgaacggcta
    15841 tcagtctttg cacacctcga tgatcggccc gcacggcgtt cctgttgaag tccagatccg
    15901 taccgaagac atggatcaga tggcggaaat gggggttgcg gcgcactggg cgtataaaga
    15961 gcacggtgag accagcacca cggcgcagat ccgcgcccag cgctggatgc agagcctgct
    16021 ggagctacaa cagagcgccg gtagttcgtt tgaatttatc gaaagcgtaa aatccgatct
    16081 cttcccggat gagatttacg ttttcacccc ggaagggcgc attgtcgaac tgcccgctgg
    16141 cgctacgccg gtggattttg cctatgcagt gcataccgac atcggccacg cctgcgtcgg
    16201 cgcgcgtgtc gaccggcagc cttatccgct gtcacagccg cttagcagcg gtcagaccgt
    16261 cgaaattatt accgcgccgg gcgcgcgtcc caacgccgcc tggctgaact ttgtcgtcag
    16321 ctctaaagcg cgcgctaaaa ttcgtcagtt gctgaaaaac ctcaaacgtg atgactccgt
    16381 aagcctgggc cgtcgtctgc ttaaccatgc tttaggcggc agtcgtaagc tggcggaaat
    16441 tccgcaggaa aatattcagc gcgaattgga tcgtatgaag ctggcaacgc ttgacgatct
    16501 gctggcggaa atcggtctcg gcaacgcgat gagcgtagtg gtcgcgaaaa atctgcagca
    16561 aggcgaagcc gtggtgccga ccgttgcgca atcgaatcac ggccacctgc cgattaaagg
    16621 cgcggatggc gtgcttatca cctttgcgaa gtgttgtcgt ccgatcccag gcgacccgat
    16681 catcgctcac gtcagcccag gtaaaggact ggtgatccac catgaatcct gccgtaatat
    16741 ccgtggatac cagaaagagc cagagaaatt tatggcggtc gaatgggaca aagagacgga
    16801 gcaggaattc attaccgaaa tcaaggtgga aatgtttaac catcagggcg cgctggctaa
    16861 cctgacggcg gcgattaata ccaccacctc caatattcaa agcctgaata ctgaagaaaa
    16921 agatggtcgc gtctatagta cctttattcg ccttaccgca cgcgatcgcg tacatctggc
    16981 gaatatcatg cgcaaaatcc gcgtgatgcc agacgttatt aaagtcaccc gtaaccgaaa
    17041 ctagcgctat gaatccaaaa cgttatgcgc gtatatgcga aatgctcgcc aggcgtcagc
    17101 ctgatctcac ggtctgcatg gagcaagtcc acaaacctca taacgtttct gcaatcattc
    17161 gtaccgcaga tgccgttggc gtccatgaag tccatgccat ctggcctggt agccggatgc
    17221 gcaccatggc ttccgcggcg gcgggcagca acagttgggt acaggtgaaa actcaccgta
    17281 ccattgacga tgcggtagcc catttgaaag gacggggaat gcagattctg gccacccatc
    17341 tttctgataa ggccgtagac tttcgcgaga ttgattacac gcgcccgacc tgtattctga
    17401 tgggtcagga gaaaaccggt attactcagg aagcattaga cctggcggat cgggacatca
    17461 tcattccgat gatcggcatg gtacagtcgc tgaacgtttc cgtcgcctcc gcgctcattc
    17521 tttatgaagc ccagcgccag cgacagaacg cgggcatgta tctgcgtgaa aatagcatgt
    17581 tgccggaaga tgaacagcag cgcctgctgt ttgagggtgg ttatccggtg ctggcgaaag
    17641 tcgctaaacg taaaggtctg ccttatcctc gcgtcaatca gcagggcgaa atcgacgccg
    17701 atgctgactg gtgggcgacg atgcaggcgg cagggtaatc accatgtcag gccgcttgtt
    17761 agacgctgtt ccgctcaatt ccctgacagg cgtcggcgca gcgcaaagca gtaaactggc
    17821 gaaaattggc ctgcataccg tccaggattt actattacat cttcctctgc gttacgaaga
    17881 ccgtacccat ctctacccca ttggcgaact gctgcctggc atctacgcca ccgttgaagg
    17941 tgaagtgctg aactgcaata tcactttcgg cggtcgccgg atgatgacct gccagattag
    18001 cgacggttcc ggcattctta ccatgcgctt tttcaatttt aacgcggcga tgaaaaacag
    18061 cctggcgacg gggcggcgtg tgctggccta cggggaagcg aagcgcggca agtatggcgc
    18121 agagatgatc catccggaat atcgcctgca gggcgatctc agcacgccgg aacttcagga
    18181 aacgctcacc cccgtctatc cgaccaccga gggcgtgaag caagcgacac tgcgcaagct
    18241 taccgatcag gcgctggagt tgctcgacac ctgcgccatt gccgaactac tgccgccgga
    18301 actggcgcag ggtatgatga gcctgccgga agcgctacgt accttgcatc gcccgccgcc
    18361 gacactccag ctcgccgatt tagaaaccgg caaacacccg gcgcagcggc ggcttattct
    18421 tgaagagcta ctggcgcata acctcagtat gctggcgctt cgcgcaggcg cgcagcgcta
    18481 ccacactcag ccgctaagta ccaacaacat attgaaagac aagctgctgg cgtcgttgcc
    18541 gtttaaaccc accagcgcgc aggcgcgggt ggtagcagag atcgaacgtg atatggcgct
    18601 ggatgtgccg atgatgcgtc tggttcaggg cgacgtcggc tcagggaaaa cgctggttgc
    18661 ggcgcttgcc gccttgcgcg ctattgccca cggtaagcag gtcgcgttga tggcaccgac
    18721 cgaactgctg gctgaacagc acgcaaataa tttccgcaac tggttcgaac cgttgggcgt
    18781 tgaagtgggt tggctggcgg gtaagcaaaa aggtaaagcg cgtcaggcgc agcaagaggc
    18841 tattgccagc ggtcaggtgc agatgattgt cggcacccac gctatctttc aggaacaggt
    18901 gcagttcaac ggcctggcgc tggtcattat cgatgagcag caccgctttg gcgtccacca
    18961 gcggctggca ttgtgggaaa aaggccagca gcagggcttt catccgcatc agttgattat
    19021 gaccgcaacg cccataccgc gcaccctggc gatgactgcc tacgccgatc tcgatacctc
    19081 ggtgattgac gagctaccgc cgggccgtac ccctgtcact accgttgcga ttccggatac
    19141 ccgtcgccat gaaatcattg atcgtgtgcg caacgcctgc acaaccgaag gccgtcaggc
    19201 ctactgggtc tgtacgctga ttgaagagtc cgacctgctg gaagcgcagg cggcggaagc
    19261 cacctgggag gagctcaagc tggcgttacc ggagttgaat atcggcctgg tacacggccg
    19321 catgaagccc gccgaaaaac aggcggtgat gcaggccttt aagcagggtg aactgcatct
    19381 gctggtcgcc acaacggtga ttgaggtggg ggtcgatgtt cctaacgcca gcctgatgat
    19441 tattgaaaac ccggagcggc tgggcctggc gcaattacac cagctcagag ggcgcgttgg
    19501 ccgtggcgcg gtcgcatcgc actgcgtgct gctctataaa tcgccgctgt cgaaaacggc
    19561 gcagaagcgt ttacaggtat tgcgcgacag caacgacggc tttgtgattg cacaaaaaga
    19621 tttagagatt cgcggcccgg gggaattact gggcacgcgc cagacgggta acgccgaatt
    19681 taaagtagct gatttgctgc gcgatcaagc catgattccc gaagttcagc gtattgcccg
    19741 tcatattcac gaacgttatc cgcagcaggc acaagcgctg attgagcgct ggatgccgga
    19801 aaccgaacgt tattctaacg cctagtgagc acggcggctt taatgccgcc gtacaaaccc
    19861 ttattgcgcg aaaatcggta acatcaagta cagcttaatc accagcgcat tgacgatatc
    19921 gataaagaac gcgccgacca ttggcaccac caggaacgcc atatgcgagg ggccaaaacg
    19981 gtcggtaatc gcctgcatat tagcaatggc ggtcggcgtt gcgcccaggc caaaaccaca
    20041 gtgacccgcc gccagcaccg ccgcatcata gtttttcccc atcatgcgcc aggtgacgaa
    20101 gatcgcgtac agcgccatga agatggtctg taccaccaga atcgccagca tcggcagcgc
    20161 cagtgacgcc agttcccaca gcttcaggct catcagcgcc attgctagga acagtgacaa
    20221 actcacgttc cccagcaccg aaacagcacg ctcaaatacg cgataaaaac ccaccagcgc
    20281 caggccattg ctgaggatca ccccaacaaa tagcacacaa acgaagaccg gcagttcaag
    20341 caccgttccc gccagtagct gcgctacgat tttgcccacg gtcagacaga tagcaatcag
    20401 ggcgatagtt tcgattagca ccagagaggt gatcatacga cccacatccg gcttttcaaa
    20461 ggctgtcggc acggcctgat cgtcaggcat tccatccggc gtggtggagt gtttcaccag
    20521 ataacgcgct accgggccgc caatcaaccc gcccagcacc aggccaaagg ttgcacatgc
    20581 catcgcaact tcggtggcac tggcaaaacc ataacgttcg acaaacagtt tactccacgc
    20641 cgcgccggta ccgtgtccgc cggacagcgt aattgacccg gcaatcagcc ccattaacgg
    20701 gtccagcccc aacagactcg ccatgccgat accgatggca ttctgcatca gcagtaatcc
    20761 gaccacgacg accaggaaga cgccaacaac gcgtcccccc ttgcgcaggc tggcaaggtt
    20821 agcgttaagg ccgatcgtcg cgaaaaacgc cagcatcaac ggatcgcgca gggtcatatc
    20881 aaagttgacc tcccaaccga cgcttttttt cagcaccagc agagcaaccg cgaccagtag
    20941 cccccccgcc accggctccg gaatcgtata tttcttcagt aaggagacag actggaccag
    21001 cttgcgaccc agtagcagca ccagcgtggc ggcgacaagg gtcgataagg tatcgagttc
    21061 aaacatttaa agctcctgta gtgcgctgtg acatgtgcgc acaaatcatt tcctgagtca
    21121 gttttttagc tctttgcgag tcttcggcat ggattttaag cagaaaaagg caaaaagtta
    21181 tataaaaggt gcatttatct tttttaaata ttaagaatat tcgctcgcaa tcgtttgctt
    21241 ttaccacctg gtcagataaa atcaccgctt ttccaccacg agaatgtccc tgatgtccgt
    21301 taacgccatc gagccggcag atgcgcaacc ggttgcgcag acgcaaaaca gcgaattaat
    21361 ttaccgtctt gaagatcgcc cgccgctccc tcaaaccctt tttgccgctt gtcagcatct
    21421 gctggccatg tttgtcgcgg taattacgcc agcgctgtta atctgccagg cgttgggttt
    21481 accggcgcag gatactcagc acattatcag catgtcgctg ttcgcctccg gcgtagcctc
    21541 tattattcaa atcaaagcgt gggggccggt aggatcgggg ctgttatcca tccagggaac
    21601 cagttttaac tttgtcgccc cgctgattat gggcggtacc gcgctgaaaa ccggcggcgc
    21661 ggatgtcccg acgatgatgg cggcgctgtt cggcacgctg atgctggcaa gctgcaccga
    21721 gatggtgctt tctcgcattc tacatctggc gcgccggatt atcacgccgt tagtctccgg
    21781 cgtcgtggta atgattattg gcctgtcgct gattcaggtg gggctaactt ccatcggcgg
    21841 cggctatgcc gccatgagcg acaacacctt tggcgcaccg aaaaacctgt tactggccgg
    21901 cgtcgtcctg gccattatca tcctgctgaa tcggcaacgt aatccctacc tgcgcgtggc
    21961 ttctttggtt attgccatgg cggcaggcta tcttttggcc tggtttatgg gcatgttgcc
    22021 tgagaataac gcgccggtct cgcaggacat cctgatggtg ccgaccccgc tgtattatgg
    22081 tctgggcatt gactggaacc tgttactgcc gttgatgctg gtctttatga ttacgtcgct
    22141 ggagaccatc ggagacatca ccgccacctc tgatgtctcc gagcagccgg tatccggccc
    22201 cttgtacatg aaacggctaa agggcggcgt actggctaac ggcctgaact catttgtttc
    22261 agcggtattt aatacgttcc cgaattcctg tttcggtcag aacaacggcg tcattcagtt
    22321 gaccggcgtc gccagtcgct atgtgggatt tgtcgtcgcg ctgatgctga ttgtgctcgg
    22381 cctgttcccg gcggtaagcg gttttgtgca acatatcccg gaaccggtgc tcggcggcgc
    22441 cacgttggtg atgttcggca ccattgccgc ctccggggtg cgtattgtct cgcgtgagcc
    22501 gctgaaccgc cgcgcgattc tgattatcgc cctgtcgctg gccgtgggtc ttggcgtctc
    22561 gcaacagccg cagatcctgc agttcgcgcc ggaatgggtg aaaaatctgc tctcatccgg
    22621 aattgccgct ggcggcatca cggctatcgt gctgaacctg attctcccgc cggaaaaacc
    22681 gtaaaaaccc tgcggcggcg acacgattcg ccgctgctgt aacgctcttt caccattcct
    22741 gtcttgagga ttgcacgcaa atcgtgcata aatcccctat gtgcatttca cgggatggaa
    22801 gaccatgaaa ttgattggga ggttgcttct ctacgtgctg atcgcctgtt tagtggtgat
    22861 tttcggcttt tattttctgc tgcaaacgcg ctggggcgca gatcatgtca gcaactgggt
    22921 atcagagaac agcggctatc acctcacatt cgacgtgatg gatcatcgtt tttccgcccc
    22981 atcccatctt ttactggaga atgtgacctt tggtcgtgat ggtcagcctg ctaccctggt
    23041 cgcgaaaacc gtagatatcg gtctgagcat tcgccagtta accgcgccgc tgcatgtcga
    23101 cacgattctg ttacaggacg gcacgctgaa tatttcagtg caaaccgccc ctttcccgtt
    23161 tgaggccgac cgcctgcaac ttcgcaatat ggcgctcaat agtcccggca gcgaatggcg
    23221 gttgagcgcc cagcgcgtta acggcggcgt tatgccctgg cgccccgaag ccggtcgggt
    23281 attgggcaat aaagcccaga tccaactga
//
LOCUS       DAJVKX010000064        23153 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000064 DAJVKX010000000
VERSION     DAJVKX010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23153
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.064"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            171..1847
                     /locus_tag="OPY25_002595"
     CDS             171..1847
                     /locus_tag="OPY25_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HCS0928184.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMIANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKSIAIPGAVAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLLDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMVEKGDVGIASLAVDMGITIGKVVAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLVLIQQPLAVLATLAIIVFGKSIAAFFLVRMFGHSPRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFTLLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGFGRVGSLLGEKLLAAGIPLVVIETSR
                     TRVDELRERGIRAVLGNAANEEIMNLAHLDCARWLLLTIPNGYEAGEIVASAREKSPD
                     IEIIARAHYDDEVKYITERGANQVVMGEREIARAMLELLETPPAGEVVAS"
     gene            complement(1896..3200)
                     /gene="gsk"
                     /locus_tag="OPY25_002596"
     CDS             complement(1896..3200)
                     /gene="gsk"
                     /locus_tag="OPY25_002596"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HCS0928185.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQIQPEQETNASWVVGIDQTLV
                     DIEAKVDDDFITRYGLSAGHSLVIEDELAEKLYQELTRENLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQAVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKK
                     HNVPVVMTLGTKFVIADNPQWWQAFLKENVSILAMNEEEAEALTGENDPLLAADKALD
                     WVDLVLCTAGPIGLYMAGFTEEEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCTNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            3353..4324
                     /gene="aes"
                     /locus_tag="OPY25_002597"
     CDS             3353..4324
                     /gene="aes"
                     /locus_tag="OPY25_002597"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HCS0928186.1"
                     /translation="MKPENKIPVLTRLSDEMTAVVNFQQPGLPPWPADGDIETQRQYY
                     LLERRFWNADAPSMTTRTCAVSTPYGDVTTRLYSPQPTSQATLYYLHGGGFILGNLDT
                     HDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCSYFSQHADEYSLNVEEIG
                     FAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYGLQDSVSRRLFGGAWDGLTR
                     EDLDMYEKAYLRNDEDRESPWYCLFNNDLTRDVPPCFIASAEFDPLIDDSRLLHQTLQ
                     AHQQPCEYKMYPGTLHAFLHYSRMMTIADDALQDGARFFMARMKTPR"
     gene            complement(4321..5283)
                     /gene="hemH"
                     /locus_tag="OPY25_002598"
     CDS             complement(4321..5283)
                     /gene="hemH"
                     /locus_tag="OPY25_002598"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HCS0928187.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLL
                     WWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSY
                     GSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIR
                     DYADDGAYIDALAKSARESFARHGEPDLLLLSYHGIPQRYADEGDDYPQRCRDTTREL
                     VSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLET
                     LEEIAEQNREIFLEAGGKKYAYIQALNATPEHIDMILKLTAPYR"
     gene            complement(5513..6157)
                     /gene="adk"
                     /locus_tag="OPY25_002599"
     CDS             complement(5513..6157)
                     /gene="adk"
                     /locus_tag="OPY25_002599"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCS0928188.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIV
                     VDYVLEFDVPDELIVDRIVGRRVHAASGRVYHVKFNPPKVEGKDDVTGEDLTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYQKEAEAGNTKYAKVDGTQAVADVRAALEKILG"
     gene            complement(6573..8447)
                     /gene="htpG"
                     /locus_tag="OPY25_002600"
     CDS             complement(6573..8447)
                     /gene="htpG"
                     /locus_tag="OPY25_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HCS0928189.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTIADNGVGMNRDEVIDHLGTIAKSGT
                     KSFLESMGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGDKPENGVFWESAGEG
                     EYTVADITKNDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEIKDDEYNEFYKHIAHDFTDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDLWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSNDLPLNV
                     SREILQDSTVTRNLRSALTKRVLQMLEKLAKDDAEKYQTFWKQFGLVLKEGPAEDHAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKNSPHLELL
                     RKKGIEVLLLSERIDEWMMNYLTEFDGKAFQSVAKADESIEKLADEVDENAKEAEKAL
                     EPFVERVKTLLGDRVKEVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQSVPEVKY
                     IFELNPDHVLVKRTADTKDEAQFKEWVELLLDQALFAERGTLEDPNQFIRRMNQLLVS
                     "
     gene            complement(8558..9163)
                     /gene="recR"
                     /locus_tag="OPY25_002601"
     CDS             complement(8558..9163)
                     /gene="recR"
                     /locus_tag="OPY25_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCS0928190.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQDVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLASEKISELILATNPTVEGEATANYIAEL
                     CAEAGVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIIF"
     gene            complement(9163..9492)
                     /locus_tag="OPY25_002602"
     CDS             complement(9163..9492)
                     /locus_tag="OPY25_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCS0928191.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            complement(9538..11466)
                     /gene="dnaX"
                     /locus_tag="OPY25_002603"
     CDS             complement(9538..11466)
                     /gene="dnaX"
                     /locus_tag="OPY25_002603"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCS0928192.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPAHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLSRAADGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAVVDANGERVMSLINEAAARGI
                     EWEALLVEMLSLLHRIAMVQLSPAALGSDMAAIEQRMRELARTVPPGDLQLYYQTLLI
                     GRKELPWAPDRRMGVEMTLLRALAFHPRMPLPEPETPRQSFAPVAPTAVMTPPQVQQP
                     SAPAPQTSPAPLPASTSQVLAARNQLQRAQGVTKTKKSEPAAASRARPVNNSALERLA
                     SVSERVQARPAPSALETTPVKKEAYRWKATTPVVQTKEVVATPKALKKALEHEKTPEL
                     AAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEQNGNAVCLHLRSTQRHLNSSG
                     AQQKLAQALSDLTGTTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQ
                     TLRRFFDAELDEESIRPI"
     misc_feature    complement(10141..10205)
                     /gene="dnaX"
                     /locus_tag="OPY25_002603"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            complement(11580..12131)
                     /gene="apt"
                     /locus_tag="OPY25_002604"
     CDS             complement(11580..12131)
                     /gene="apt"
                     /locus_tag="OPY25_002604"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCS0928193.1"
                     /translation="MTATAQQLEFLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IELLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPRKLPRETIAETYEL
                     EYGTDQLEIHVDAIKPGDNVLVVDDLLATGGTIEATVKLIRRLGGKVTDAAFIINLFD
                     LGGEQRLEKQGITCYSLMPFPGH"
     gene            complement(12284..12661)
                     /locus_tag="OPY25_002605"
     CDS             complement(12284..12661)
                     /locus_tag="OPY25_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HCS0928194.1"
                     /translation="MQRTILIIIGWLAVVLGTLGVVLPLLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGGYLRHWQRYRAMPPGAKPRAIALILLTFGISLWLVNMMWVRVLLL
                     VILACLLIFMWRIPVIDEKQQKR"
     gene            12730..13257
                     /gene="priC"
                     /locus_tag="OPY25_002606"
                     /pseudo
     CDS             12730..13257
                     /gene="priC"
                     /locus_tag="OPY25_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519637.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
     gene            13271..13438
                     /gene="rsmS"
                     /locus_tag="OPY25_002607"
     CDS             13271..13438
                     /gene="rsmS"
                     /locus_tag="OPY25_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HCS0928195.1"
                     /translation="MSLENAPDEVKLAVDLIVLLEENRLPARTVLRALEIVMRDYENK
                     LKSTEDDSQTE"
     gene            13508..14431
                     /locus_tag="OPY25_002608"
     CDS             13508..14431
                     /locus_tag="OPY25_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCS0928196.1"
                     /translation="MERLPTTPHDAVFRQMLMQKEVARDFLAIHLPEDFLAICDLDSL
                     KLESGSFVEDNLRSRYSDILYSLHTQHGPGYVYALIEHQSKSDRLMAFRLMRYAIAAM
                     QRHLDAGHDTLPLVVPILFYHGPESPWPYSLNWHNMFVKPDMAKALYSHEFALVDLTI
                     MPDNQLLQHRRIAMLELLQKHIRQRDLSELLDPLITLLTQDHLTDAQLSVLINYMLKA
                     GNAAEPGALIRQLAQGAPQYKEQLMTIAEWLEEKGRTEGLRKGLEQGLAQGREAEARA
                     IARKMLANGLEPGLIASVTGITPEELSTLSH"
     gene            complement(14473..17835)
                     /gene="mscK"
                     /locus_tag="OPY25_002609"
     CDS             complement(14473..17835)
                     /gene="mscK"
                     /locus_tag="OPY25_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HCS0928197.1"
                     /translation="MTMLQLYKRSQHFVFITISVLIILLSCQSLAFARGQTNGDLPSK
                     ADVQNQLDTLNKQKDLSAQDKLVQQDLIDTLATLEKIERVKEETVQLRQKVAQAPEKM
                     RQATAALNALSDVDNDDEMRKTLSALSLRQLELRVAQVLDDLQNSQNDLAAYNSQLVS
                     LQTQPERVQNAMYTASQQIQQIRNRLDGNNVGEAALRPSQQVLLQAQQALLNAQIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSNRLEHQLQLLQEAVNSKRLTLTEKTAQEAISPD
                     ETARIQANPLVKQELDINHQLSQRLIVATENGNMLMQQNIKVKNWLDRALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELEDMTNRIADLRLEQFEINQQRDALFQSDAF
                     VDKLEEGHTSEVNDEVHDALLQVVEMRRELLDQLNKQLGNQLMMAINLQVNQQQLMSV
                     SKNLKAILTQQIFWVNSNRPMDWDWLKAFPQTLKEQFSAMKITVNWQKAWPAVFIAFL
                     AGLPLLLIAGLIRWRLKWLKAYQQKLAAAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAIGLILLTMQLNISDLLWAFSKKLAMFWLVFGLCWKVLEKEGVAIRHFGMPAQLTS
                     HWRRQIVRISLALLPLHFWSVVAELSPLNLMDDVLGQAVIFLNLLVITLLVWPLCRES
                     WRDKESHGIRLVTVTILSIIPVALMVLTATGYFYTTLRLAGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPQEEPTIALEQINQQTLRITMLLM
                     LALFGVMFWAIWSDLITVFSYLDSITLWHYNGSEAGAAVVKSVTMGSLLFAIIAAMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYVIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTYSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLSDTTTRLVIRLGVAYGSDLEKVKRVLLQAAMEHP
                     KVMHDPEPAVFFTTFGASTLDHELRLYVRELRDRSHTVDELNRAIDRLCRENDINIAF
                     NQLEVHLHNAKGDEVTEVKRDLNGGDLAPAAS"
     gene            complement(17954..18607)
                     /gene="acrR"
                     /locus_tag="OPY25_002610"
     CDS             complement(17954..18607)
                     /gene="acrR"
                     /locus_tag="OPY25_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HCS0928198.1"
                     /translation="MARKTKQQALETRQHILDVALRLFSQQGVSATSLAEIANAAGVT
                     RGAIYWHFKNKSDLFSEIWELSESNIGELEIEYQAKFPDDPLSVLREILVHILEATVT
                     EERRRLLMEIIFHKCEFVGEMVVVQQAQRSLCLESYDRIEQTLKHCINAKMLPENLLT
                     RRAAILMRSFISGLMENWLFAPQSFDLKKEARAYVTILLEMYQLCPTLRASTVNGSP"
     gene            18749..19942
                     /gene="acrA"
                     /locus_tag="OPY25_002611"
     CDS             18749..19942
                     /gene="acrA"
                     /locus_tag="OPY25_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HCS0928199.1"
                     /translation="MNKNRGLTPLAVVLMLSGSLALTGCDDKQDQQGGQQMPEVGVVT
                     LKTEPLQITTELPGRTVAYRIAEVRPQVSGIILKRNFVEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAELTVKRYQKLLGTQYISKQEYDQALADAQQATAAVVAA
                     KAAVETARINLAYTKVTSPISGRIGKSSVTEGALVQNGQASALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGSLKQENGKAKVDLVTSDGIKFPQSGTLEFSDVTVDQSTGSITL
                     RAIFPNPDHTLLPGMFVRARLQEGTKPTALLVPQQGVTRTPRGDATVLVVGADNKVET
                     RQIVASQAIGDKWLVTDGLKAGDRVVVSGLQKVRPGAQVKVQEITADNKQQAASGDQP
                     AQPRS"
     gene            19965..23114
                     /locus_tag="OPY25_002612"
     CDS             19965..23114
                     /locus_tag="OPY25_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HCS0928200.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDPISRTSGVGDVQLFGSQYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYD
                     VIAKFNGQPASGLGIKLATGANALDTATAIRAELKKMEPFFPPGMKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMTEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPVAKGDHGEG
                     KKGFFGWFNRLFDKSTHHYTDSVGNILRSTGRYLLLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFLTMVQLPAGATQERTQKVLDEVTDYYLNKEKANVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEKNKVEAITQRATAAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVRPNGLEDTPQFKIDIDQEKAQALG
                     VSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDINDWYVRGSDGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEELASKLPSGIG
                     YDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLVEAMLEAVRMRL
                     RPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKSEDIEHSHSTEHR"
BASE COUNT         5204 a         6373 c         6178 g         5398 t
ORIGIN      
        1 atgccatctt gctttgtcca tcccatgctt atcactttta cgttccatgc tctttttgcc
       61 ttcagatcgt atctttttat aaaacacaac cattttttat aaacatcctg attgaaattg
      121 tcataaacta ttacccggag ttttggagtc cagcaaccaa aggagacgga atgcatcacg
      181 ctaccccgct tatcaccacc attgtcggcg gccttgtgct cgcttttatt ctcggcatga
      241 ttgccaacaa attgcgtatt tctccactgg tgggatatct gttagcgggc gttctggcgg
      301 gaccttttac cccaggtttt gttgcggata ccaaactggc gccggagctg gcggagctcg
      361 gcgtgattct attgatgttc ggcgtcgggc tgcatttttc gctgaaggat ttgatggcgg
      421 taaagtctat cgccattccc ggcgctgtcg ctcagatagc ggtggcgacg ctgctgggta
      481 tggcgctttc cgccgtgctg ggatggtcat taatgaccgg catcgttttt gggctctgtc
      541 tgtctaccgc cagtaccgtc gtcctgctgc gcgcgcttga ggagcgacaa ctccttgata
      601 gccagcgcgg gcaaatcgcc atcggctggc tgattgtcga agatctggtg atggtgctga
      661 cgctggtctt gctgcccgcc gttgccggca tggtggaaaa aggcgatgtc ggcatagcct
      721 cgctggcagt cgatatgggg ataaccattg gtaaagtggt ggcgtttatc gccatcatga
      781 tgctggtcgg acgccgcctg gtgccgtgga ttatggcccg cagcgccgcc accggctcgc
      841 gcgagttatt taccctttcc gtactggcgc tggcgttagg cattgcgttt ggcgcggtag
      901 aactgtttga cgtctctttt gcgctgggcg cgttcttcgc tggaatggtg cttaatgagt
      961 cggaactgag tcaccgggcg gcgcacgata cgttgccact gcgcgacgcc tttgccgtcc
     1021 tgttttttgt ttccgtcggc atgttgttcg atccgctagt cttgattcaa cagccgctgg
     1081 cggtgttggc gacgcttgcc attatcgtct ttggtaaatc gatcgctgcg tttttcctgg
     1141 tgcgtatgtt cggccactcg ccgcgaaccg cgctgaccat tgccgccagc ctggcgcaaa
     1201 tcggtgagtt cgcctttatt ctcgccggac tcggtatggc gctcaatctg ctgccgcagg
     1261 cgggacagaa cctggtgctg gcaggcgcta ttttgtcgat tatgcttaat cccgtactgt
     1321 ttaccctgct ggagaagtat ctggcgaaaa ccgaaacgct ggaagagcaa actctggaag
     1381 aggctatcga agaagagaag caaattccgg tggatatctg taatcatgcc ctgctggtgg
     1441 gttttggccg cgtaggcagt ctgctgggag aaaaattact ggcggcgggg attccgctgg
     1501 tggttatcga aacgtcccgt acccgcgtgg atgaactgcg cgaacgcggg attcgcgccg
     1561 tactgggcaa cgccgctaac gaagaaatca tgaatctggc gcatctggac tgcgcccgct
     1621 ggctgttatt gaccatcccc aacggttacg aagccggtga gattgtcgcc tcagcgcgag
     1681 aaaaaagccc tgatatcgag ataatcgccc gcgcgcacta tgatgatgaa gtgaaatata
     1741 ttaccgagcg gggagccaat caggtagtga tgggcgagcg agaaattgcc cgggcgatgc
     1801 tggaactgct tgaaacgccg cccgcgggtg aagtcgtcgc cagttaaggg tttgccggac
     1861 ggcccgatgc gcgcagcgcc atcgggcaag ccagattagc gatcccagta cgactcttcc
     1921 aggctgtcct cacgttccgg cagcccgcgt gtcagacgcg gagaatgctg gttcagtacc
     1981 tgataactga cacggttagc atatttacac acctgcgcca gcgacgaata ggtcagccag
     2041 gtgaatttgt gcttactgga gttcggtacg ttgctacgat ggtaactgtt cgccgtaata
     2101 tcgtgcagca gcgccgccag cgcgccatcg cccgcgccgt tggtgttcat gattttttcc
     2161 ggcccgccca tatacggcgc aatatgcgaa taaacgcgca gcggattagt acaatcttta
     2221 tggcgcattg cccggctaaa ttcatactgg ttaaattcag caatagcccc cggcagcaga
     2281 ggatgctggg ttttacgttt tgcttcctct tcggtgaagc ctgccatata taaccctatc
     2341 ggcccggcgg tgcataacac caggtcgacc cagtccagcg ccttatccgc cgccagcagc
     2401 gggtcgtttt cgccggtcag cgcttccgct tcttcttcat tcattgccag aatcgagaca
     2461 ttctctttga gaaacgcctg ccaccactgc ggattatcgg cgatcacaaa tttggtgccc
     2521 agcgtcatga caaccggcac gttatgcttt ttcgcgtatt cgatcgcttt catcgtcgcg
     2581 tcaggcatcg gttcgccagg cttacagcgc accagatatg aggtcaacac cagcgcggaa
     2641 gcgccagcga tcaccgcttc cggaatactt tccgcccgta gctgattcat atggccgggg
     2701 ctgatagcga aggtacgctc gccggattcg ccaatcagcg tgaaacagcg gccaatcgga
     2761 ccatctaccg cttgcagata attcaggtcg gtacggctgg aagtattaca caggtagcga
     2821 taagcgtagc tgccaatctc aatgttgctg cacatcacgc ccagtaacac cgaacggtca
     2881 tccgccagta ccgagtaatt atgcatcgta ttgcctatgg tgccgccagc aaactgatgg
     2941 gtgatcagat tttcccgcgt cagttcctga tacagcttct ccgccaactc gtcttctatc
     3001 accagagaat gcccggcgct taatccatag cgtgtaataa aatcgtcatc cactttcgcc
     3061 tcaatatcca ccaacgtctg gtcgataccg acgacccagg aggcgttggt ttcctgttct
     3121 ggctgaattt gttgcaacaa cgggtcacgc gcattgacgg gaaaatagtg tttggattta
     3181 cgtttaccgg gaaatttcat gattgtgctt acggatgaat aacggagcgc tgcatggtag
     3241 cacattcccc ctgctgcgcg cgacggacga tggcgtttca atatcggacg acgagatcgc
     3301 agtttctcca gccgcgtttt ttacaatggt tcactttcac aaggagcgtt ttatgaagcc
     3361 ggaaaataaa attcccgtac tcacccgact gtctgacgaa atgacagccg tcgtaaactt
     3421 ccagcaacca ggccttcccc cctggcctgc cgatggcgat attgagaccc agcgtcagta
     3481 ttatcttctt gagcgccgtt tctggaatgc cgacgcgccg tccatgacca cccgcacctg
     3541 cgccgtctct acgccttatg gcgatgtaac aacccggctc tactcgccgc agccgaccag
     3601 tcaggccacc ttatactatc tgcacggcgg cggatttatc ctcggtaatc tggatacgca
     3661 tgaccggata atgcgtctgc tggcgcgtta taccggctgc accgtgatcg gtattgatta
     3721 ttcgctgtcg ccgcaagcgc gttatccgca ggccattgaa gaaaccgtcg cggtatgcag
     3781 ctacttctct caacatgccg atgaatactc gctcaacgtg gaggaaatcg gtttcgccgg
     3841 agattccgca ggcgccatgc tggcgcttgc cagcgcgctc tggctacgtg ataagcacat
     3901 tcgctgcggt aacgttatcg cgattctgtt gtggtatggg ctgtatgggt tgcaagattc
     3961 ggtaagccgc cgtctgttcg gcggcgcgtg ggacggcctg acgcgtgaag atctggacat
     4021 gtacgaaaag gcctatctgc gtaacgatga agatcgggaa tcgccctggt attgtctgtt
     4081 taataacgat ctcacgcgcg atgtgccgcc ctgctttatt gccagcgcgg agtttgatcc
     4141 gctcattgat gacagccgct tgctgcacca gacattacag gcgcaccagc agccctgcga
     4201 atacaaaatg tatcccggca cgctgcacgc cttcctgcac tattcgcgaa tgatgacaat
     4261 cgccgacgat gccttgcagg acggcgcacg cttctttatg gcgaggatga agacgccgcg
     4321 ttaacggtac ggcgccgtga gtttcagtat catatcaata tgttccggcg tcgcgttcag
     4381 cgcctgaatg tacgcatatt ttttaccgcc cgcttcaagg aaaatctcgc ggttctgttc
     4441 cgctatctct tccagcgtct ccagacaatc cgcggcaaac cccggacaca tgacctgaat
     4501 atggccagtc cccttttcac ccaacatttt tagcgtttca tcggtgtacg gcgtcagcca
     4561 cggttcacgg ccaaagcgcg actggaacgt catcattacc ttttccggcg gcagtcccaa
     4621 tgcggaaacc agttcacgcg tggtatcgcg acagcgctgc gggtagtcat cgccttcatc
     4681 cgcataacgt tgtggaatgc cgtgatagga gagcagaagt aaatccggct cgccgtgtct
     4741 ggcgaacgac tcacgcgcgc ttttcgccag cgcatcgata taagcgccgt catccgcgta
     4801 atcgcgaata aatgagatcc cgggaatacg acgtttacgc gccagtatcc gccccagttc
     4861 gtcccagact gcgcccaccg ttgagcaaga atattgcggg tacaacggca gcacgacgat
     4921 atggtcgacg tcgcttgcta acagttcatc gacagcgctt tccagcgagg gcgagccgta
     4981 gctcatcccc agcgcgacgg gcgtgtctgg caaccgcgcg gccagcgcct gttgctgttc
     5041 gcggctatat accatgagcg gcgaaccgcc atccatccag atagattgat agagtttcgc
     5101 gacgcgcggc gaacgcagcg gtaaaataac gccacgcagc agcggccacc acagcagacg
     5161 aggagtatcc accacgcgtc tgtcgcttaa aaattgtttc aggtagcgct ttaccgcttc
     5221 aggagttggg gcatctggcg tgccaaggtt agccagcagg ataccggttt tcgtctgacg
     5281 cattgccgcc tcttatctat tcaaattgtt gataattgta gcggaaaagc gataaagaag
     5341 aactaattgc tgcgagaggt aagacgagaa tttgccgaat ggcgctaacg ataccggtag
     5401 gccggataag gcgttcaggc cgccattcgg caccgattgc ctgatggcgc tacgcttatc
     5461 aggcctgcgg gataatggca ggcctgataa gcggttcact acgcgaaaaa aattaaccga
     5521 ggattttttc cagcgctgcg cgcacgtcgg caacggcctg cgtaccgtca actttagcgt
     5581 atttggtgtt gcccgcttcc gcttctttct ggtagtagcc aatcagcggc gcggtcatct
     5641 gatgatattc caccagacgt ttgcgaacgg tctcttcctg atcgtcttta cgggtcgtca
     5701 gatcttcgcc ggtgacgtca tctttgcctt ccactttcgg cggattaaac ttaacgtggt
     5761 aaacgcggcc agaggcggcg tgtacgcgac gacccacaat acggtcaacg atcagttcgt
     5821 ccggtacgtc gaattccagc acgtaatcca ccacaatacc cgcttctttc atcgcgtcag
     5881 cctgcgggat cgtgcgcggg aaaccgtcca gcagaaaacc gttacggcag tcttcctggg
     5941 cgatacgctc tttaaccagc gcaatcacca gttcatcggt caccagttta ccggcgtcca
     6001 tgatatcttt cgcctgtttg cccaactcgg agcctgattt cactgcggcg cgcagcatat
     6061 cgccagtgga gatttgcgga ataccatatt tctccatgat gaactgagcc tgagttcctt
     6121 tacccgcgcc cggagcgcca agcagaataa tacgcattac gaaaatcccc tcaaaggttg
     6181 tcgatatttt ttaaaaagcg ctaaacgata ccaccatcac gcatttcgct caaggaagtc
     6241 gcctgatgct gaaacggtta acgaagagaa atccagaaaa gagaaggtat tataaaaaat
     6301 gccggatggc gctggcgctt atccggccta caaacagtac tcgtccgtag gccggataag
     6361 atgcttcgcg tcgccatccg gcagtcacaa aacagtactc gcccgtaggc cggataagac
     6421 gcttcgcgtc gccatccggc agtcacaaaa cagtacccgt ccgtaggccg gataagatgc
     6481 ttcgcgtcgc catccggcag tcacaaaaca gtacccgccc gtaggtcggg taagacgctt
     6541 cgcgtcgcta tccggcaatc agatgagcgt tatcaggaca ccagcaactg gttcatacgg
     6601 cggataaact ggttcggatc ttccagcgta ccgcgttcag cgaacagcgc ctgatccagc
     6661 agcagctcga cccactcttt aaactgcgct tcatccttgg tatcggcagt gcgtttgacc
     6721 agcacatgat ccgggttgag ctcaaagatg tatttcactt ccggcacgga ctgaccggcc
     6781 gcggcgaaca gtttcgccat ctgggtgctc atttcatccg catcggtggt gacaatcgcc
     6841 ggcgtgtcgg ttaaacggtg tgtcagacgc acctctttca cgcgatcgcc cagcagggtt
     6901 ttgacacgct ccacgaacgg ctcaagcgcc ttttccgctt ctttcgcgtt ttcgtcgact
     6961 tcatccgcca gtttttcgat ggactcatcg gctttagcga ccgactggaa tgctttaccg
     7021 tcaaactcgg tcaggtagtt catcatccac tcgtcgatgc gctcggagag cagcagcact
     7081 tcgatgcctt tcttacgcag cagctccagg tgcgggctgt ttttcgccgc cgcatagctg
     7141 tctgcggtga tgtagtagat tttttcctgc ccttctttca tccgggagac gtaatcttcc
     7201 agcgacacgg tctgggcgga agagtcggta tgggtggagg caaagcgcaa cagtttagcg
     7261 atcgcttcct ggttggcgtg atcttccgcc gggccttctt tcaacaccag accgaactgt
     7321 ttccagaagg tttggtattt ttccgcgtcg tctttcgcca gtttttccag catttgcaga
     7381 acgcgtttgg tcagggcgct gcgcagatta cgcgttaccg tgctgtcctg caggatttca
     7441 cgggagacat tcaacggcag gtcattagaa tcaatcaggc cgcgcacgaa acgcagatag
     7501 ttcggcatga actgctcggc atcgtccata atgaacacac gctgtacgta cagcttcaga
     7561 ccatgtttgt gatcgcggtt ccacagatcc cacggcgcct gcgacgggat atacagcagg
     7621 ctggtgtact cctgcttacc ttccacgcgg ttgtggctcc aggtcagcgg atcggtgaaa
     7681 tcatgcgcga tgtgcttgta aaactcgttg tactcgtcgt ctttaatttc cgacttgtta
     7741 cgggtccaca acgcctgggc cttgttgatt ttctcccagg aaatcacggt ttcgccgtct
     7801 ttttcttccc gtttttcaat ctctaccggc aatgcgatgt gatcggaata tttactgata
     7861 attgagcgta cgcgccagtc atcgaggaat tcatcttcgc cttcacgcag gtgtaaggtg
     7921 atttccgtac cacggtcatt tttggtgata tcggcaacgg tatattcgcc ttcgcctgcc
     7981 gattcccaga acacgccatt ttccggcttg tcgcctgccg cacgggtacg tacggtcact
     8041 ttatcggcca caataaacgc ggagtagaag cctacgccaa actgaccgat gagctggcta
     8101 tctttcgcct gatcggaccc cattgattcg aggaaagatt tggtgccgga cttggcaatg
     8161 gtgcctaagt ggtcaatcac ctcatcacga ttcatcccca cgccgttatc ggcaatggtc
     8221 aacgtacgct tatctttatc gaaagagacg cgcacacgca gctcgccatc tccttcatac
     8281 aggtccgggt ttgacagagc gcggaaacgc agcttgtccg ccgcatctga ggcgttagag
     8341 atgagttcac gcaggaagat ttctttattg gaataaagag aatggatcat caggtgcaga
     8401 agctgtttaa cttctgactg aaaaccacgc gtttcttgtc ctttcatgtg gatagacctc
     8461 aacaatgcca tttttaatgg taaaaatacg ttgagggtga gatggggaca agcgggtgtg
     8521 atttcaagcg gaggccgcga acgccgcctc cgtttgttca gaaaataatc ttatggcgtc
     8581 ccgccagcga gtgggacagc gtcgtaccgt cgaccatctc cagttcgccg ccaaccggca
     8641 cgccgtgggc gatacgactg gcttcgacgc cggcctccgc gcacagctcg gcaatatagt
     8701 tcgcggtagc ctccccttca accgtcgggt tggtcgcgag gatcagctcg ctgatttttt
     8761 ctgacgccag ccgctgttcc agacgatcga gaccgatatc atccggcccg atgccgtcca
     8821 gcggcgacag gtggcccatc agcacgaaat accgcccgga aaattgcccg gtctgctcaa
     8881 tggcgtagat atccgcagga ctctccacca cgcaaatctg gccgttttcc tggcgccgcg
     8941 ggttcgaaca gatattacaa acatcctgct cggtaaaggt gcggcagtcg gcgcagtggc
     9001 cgatttccga catcgcccgg gtcagcgcct gcgccaggcg cattccgccg ctacgatcgc
     9061 gctgcaacag ggtaaacgcc atccgttgcg ccgacttagg gccgacgccc ggaaggcagc
     9121 gcaacgcttc cataagctga gttaacagcg gactggtttg catcagaatg gcatcttaaa
     9181 gcctggcggc agttgcatac cggaagagac ggaagccatc ttctcttttt gcgtctcttc
     9241 aatgcggcgc gccgcatcgt tgaaggccgc agcgaccaga tcttccagca tctctttgtc
     9301 atcttccagc aggcttgggt caatttccac acggcggcag ttatgcgcac cgttgatggt
     9361 aaccttcacc agacccgcgc cggattcgcc ggtcacttcc agctgcgcaa tctcttcctg
     9421 cattttctgc attttttcct gcatctgctg ggcctgcttc atcagattgc ccagaccgcc
     9481 ttttccaaac ataagctctc tctcttgatg gttcacaatc gcaagccggg cttacgatca
     9541 aatggggcgg atactctctt catccagctc ggcgtcgaag aatcgacgca gcgtctgaat
     9601 gttattatcc gcgataattg actcacgcgc ttgcgcgagt ttctcttcat aaatggcctg
     9661 acgccattcc agcggcgtac gcaccgcggg attatcatct tcaacgatgg tcagttcaac
     9721 cgtcgttccc gtcagatcgc tgagcgcttg cgccagcttt tgctgcgcac cgctggaatt
     9781 gaggtgccgc tgcgtcgagc gcagatgcag acaaaccgcg ttgccgttct gctccttcca
     9841 ggcattgagc gccacctgct ccaccagctt aggcaaagaa agctggctta cctgcgccgc
     9901 ccacggatcg cgctcaatcg cttccgccgc cagtttagcc gccagctccg gcgttttttc
     9961 atgctccaga gctttcttaa gcgcttttgg cgtagccacc acttctttgg tttgcactac
    10021 cggcgtggtg gccttccagc gataagcctc tttctttact ggcgtcgttt ccagcgcaga
    10081 cggcgccggg cgcgcctgta cgcgctccga aaccgaggcc agccgctcca gcgcagagtt
    10141 attcaccggc cgcgcgcggg atgcggctgc cggttcactc ttttttgttt tggttactcc
    10201 ctgcgcgcgc tgtagctgat tgcgcgccgc cagcacctga ctggtagacg ccggcagcgg
    10261 cgctggcgat gtctgcggcg cgggcgccga cggctgctgc acctgcggcg gcgtcattac
    10321 cgccgttggg gccacgggcg caaaagactg ccgcggcgtt tcaggctccg gcaagggcat
    10381 acgcgggtga aacgccagcg cacgcaataa cgtcatttca acgcccatcc gccggtccgg
    10441 cgcccagggc aattctttgc gaccaatcaa caacgtctga taatagagct gaagatcgcc
    10501 gggaggcacc gtccgggcaa gttcgcgcat ccgttgctcg atagccgcca tatcgctgcc
    10561 taacgcggca ggcgaaagtt gcaccatcgc aatacggtgc agcaggctaa gcatttcgac
    10621 cagcagcgct tcccattcaa taccgcgcgc cgccgcctcg ttgataagcg acatgacgcg
    10681 ttcgccgtta gcgtcaacca ctgcctcgac taatgacaaa gcctggtcgt cgtccagcgt
    10741 accgagcatg gcgcttaccg cctgcgtcga aacctgcccg tcgccactgg cgatcgcctg
    10801 gtcagtcaga cttaatgcat cgcgcaggct gccgtcagcc gcgcgtgata acaactgcaa
    10861 cgcgcggggt tcgtgagcga tatgttcctc attgagaata tgctcaagct gatggcgaat
    10921 ctgttcaaca tccagcgctt tgagatgaaa ctgtaggcag cgcgacaaaa tggtcaccgg
    10981 cagcttctgc ggatcggtgg tcgccagtaa aaatttcaca tgcgctggcg gctcttcaag
    11041 cgttttaagt agcgcattaa agctgtggcg cgacagcatg tggacttcat cgatcagata
    11101 gactttaaag cgaccgcgcg caggcgcgta ctggacgtta tccagcaggt cgcgggtgtc
    11161 ttcgactttg gtacgcgatg cggcgtcaat ctcaatgaga tcgacaaaac gcccttgctc
    11221 aatttcccga cagttatcgc aaacgccgca cggcgtcgcg gtaataccgg tttcgcagtt
    11281 cagccccttc gccagcagtc gggcgataga agttttaccg acgccgcgcg tgccggaaaa
    11341 aagatatgcg tgatgaatgc gccctaacga caagccgttc gccagtgcgg tcagcacatg
    11401 ttcctggccg acgacgtcag caaaggtttg tgggcgccat tttctggcta agacctgata
    11461 actcattggc aggctctgaa acgctggaag gtggattcat agaagggtaa tgctaacaca
    11521 acctcgccga tacagcgagg ttgtctctct ggctaaaata gcagtgcgaa tagcctgaat
    11581 caatgccctg gaaacggcat caggctataa caggtaatcc cctgcttttc cagacgctgc
    11641 tcgccgccca gatcgaacaa attgatgatg aacgccgcat cggtgacttt cccgcccaga
    11701 cgacggatca gcttcacggt cgcctcaatg gtgccgccag tcgccagcag atcgtccacg
    11761 accagcacgt tgtcgccagg tttaatcgcg tcgacatgga tttccagctg atcggtgccg
    11821 tactctaatt cataggtctc ggcaatagtt tcacgcggta atttgcgcgg tttacgtacc
    11881 ggaacaaaac caacgcccag cccaagcgca accggcgcgc caaacaggaa gccacgcgct
    11941 tcggtgccga ccactttggt gatacccgca tttttataac gctcaactaa cagttcaata
    12001 ctgagcgcgt aggctttcgg gtcttccagt aagctggtga catcacggaa aagaatgccc
    12061 ggtttcgggt aatcctgaat gcttttgatg ctgtttttga gaaactcaag ctgctgtgca
    12121 gtcgcggtca tggatatatg cctgctaagt acggtgttac tcacggcgca atacttttca
    12181 gtcaggggta acgctcggtt actctttgac cgcctgcgcc tgtgctcgaa aacggtcgaa
    12241 tttactggct gtgaacgaca attgcaacag cgattcgtgt gcttcagcgc ttttgttgct
    12301 tttcatcaat caccggtatc cgccacataa aaatcagcag gcaggccaaa ataaccaaca
    12361 gcagcacccg cacccacatc atattcacca gccacagcga aataccaaag gtcagcaata
    12421 tcaacgcgat cgctcgcggt ttcgctcccg gcggcatggc ccgatagcgc tgccagtggc
    12481 gcagataacc gccaaaccat gagcggtata acaaccaagc atggaaacgc ggcgacgagc
    12541 gggcgaaaca ccaggctgcc agtaaaatga acggcgtagt cggcaacagg ggcaaaacca
    12601 cgcccagtgt ccctaatact accgccagcc agccaatgat gattaaaata gtacgttgca
    12661 taatgcgaat cgttatcaaa cagaaggcta ctgtagcaca gcctgtctta ttttcatcgg
    12721 ggtgttgaat tgaaaaccgc tatgctgtta cagacgctgg aagagaagct ggcgacgcta
    12781 cgccaacgct gcgcgccgct ggcgtaacat gcgacgttaa gcgcgcgctt tgaccgacac
    12841 cttttccgta cccgcagtac tctgttgcag ggatatctgg aagaggcaga cgccaatctc
    12901 gccgcgttgc gtcaggcggt aaaacatgag caactgccgc aagtcgcctg gctggcggaa
    12961 catctggctt cgcaactgga ggcgatatcg cgtgaaaccg ccgcctggtc gctgcgccag
    13021 tgggatgccg ccgcaccagg gcttggccgt tggcagcgca gacgaataca gcatcaggag
    13081 tttgaatgtc gactgctggc gatgacacag gagcgcaaaa ttcgtctggc gcaggcgacc
    13141 ggccttgtcg aacaacaaac gctgcaaaag gaagtcgaga tctatgaagg acggctggcg
    13201 cgctgccgac atgcgctgga gaaaatagaa aacgtactgg cgcgtttacc ccgttaaccc
    13261 aggagaaagt atgtcgcttg aaaatgcccc tgatgaagtc aaactggccg tggatttaat
    13321 tgtgctgctt gaagagaatc gcttaccggc acgaacggtg ctacgcgcgc tggaaatagt
    13381 tatgcgtgat tatgaaaaca agttaaaaag tacggaagac gactcgcaaa cagagtaata
    13441 gccccctggt ttgtcctcgt tgtcgctgac aaagtggtcg ctacagtcag gcaacaaagg
    13501 acggggcatg gaacgtctac ccaccacgcc gcacgatgcg gtattccgac agatgctgat
    13561 gcaaaaagag gtcgcccgcg actttctggc tatccacttg ccagaagact ttcttgcaat
    13621 ctgcgatctg gattcactga agctggagtc ggggagtttt gttgaagaca atttacgcag
    13681 ccgctattca gatattctct actctctgca tacccaacac ggccccgggt atgtttacgc
    13741 gcttattgaa catcagagca aatcagaccg gctgatggct tttcgcctga tgcggtacgc
    13801 cattgccgcc atgcagcgtc atctggatgc cggccatgat accttgccgc tggtggtacc
    13861 aatcctcttt tatcacggtc cggaaagccc gtggccctat agccttaact ggcataatat
    13921 gtttgtgaaa ccggatatgg cgaaagcctt atacagtcat gaatttgcgc tggtcgacct
    13981 aacgataatg ccggataatc agcttttgca gcatcggcgg atagcgatgt tagagctcct
    14041 gcaaaaacat attcgtcaac gcgatttaag cgaactgctc gaccccctta tcacgctttt
    14101 aacgcaggat catttgacgg acgcgcagct cagtgtgctg atcaactata tgttgaaagc
    14161 aggaaacgcc gcagaacccg gggcgctaat tcgtcaactg gcgcagggcg cgccgcagta
    14221 taaggaacaa ctgatgacaa tagcggaatg gctggaagaa aaaggccgaa cggaagggtt
    14281 gcgaaaaggg cttgagcaag ggttggcaca aggccgtgag gccgaagcgc gcgctattgc
    14341 ccgcaaaatg cttgccaacg ggctggaacc cgggctcatc gccagcgtca ccggcattac
    14401 gccggaagag ctttctacgc tttcgcatta gcggcgccgc gcgcactcat aaagcgcgcg
    14461 gcccaccgcc ttttagcttg ccgccggcgc cagatcgccg ccgttgagat cgcgcttcac
    14521 ttcagtgact tcgtcgccct tcgcgttatg cagatgcacc tcaagctggt taaaggcaat
    14581 attgatatca ttttcacggc acagtcgatc gatcgcgcgg ttcagttcat ccaccgtatg
    14641 gctacgatca cgcaattcac gcacatacag acgcagttca tgatccagag tgctggcgcc
    14701 aaaggtggtg aagaatacgg caggttccgg atcgtgcatc accttcggat gctccatcgc
    14761 cgcctgtagc aggactcttt tcactttctc cagatccgag ccataggcca cgccaagccg
    14821 gatcaccaga cgtgtcgtgg tatcggagag ggaccagtta atcagccgct ccgttacgaa
    14881 cgctttgttc ggaatgatca cttctttacg atcaaaatcg gtaatagtgg tggcgcgaat
    14941 acgaatctta ctgaccgtgc cggagtaggt gccgatcgtt accgtatcgc caatgcgtac
    15001 cggacgttcg aagaggatga ttaaacccga gacaaagtta ccgaagatct cctgtagccc
    15061 aaaaccgaga cctaccgaca acgccgccgc cagccactgg agtttatccc acgagacgcc
    15121 gagcgatccg aatactgtca tcgcgccaac agcgataatg acgtagttaa ggatcgtggt
    15181 gatcgcatac gaagcccctt ggcgcatatt caggcgtgaa agcaccagca cttccagcag
    15241 gccgggtaag ttgcggatga gcgcccaggc caccatcgcg gcaataatgg caaatagcaa
    15301 gctgcccatc gtcacgcttt tcaccaccgc agcgccagct tcggagccgt tgtagtgcca
    15361 cagcgtgatg ctatcaagat agctgaatac ggtgatcaaa tcggaccaaa tcgcccagaa
    15421 cataacgcca aacagggcaa gcattagcag catcgtgata cgtaatgttt gctggttaat
    15481 ttgctccaac gcgatggtgg gttcttcctg tggttccgcc ccttccgctc cctcttttac
    15541 caggttctga cgacgagcca gcgcgcgtcg ccaggcaatc cggcgcgccg ctacacttaa
    15601 cccgcgcagc accgtttgat aaagcaggtt ccagataatg accagataga cggtttcaat
    15661 ccagcgcccc gccaggcgca gggtggtata gaaatagcca gtcgccgtta ataccattaa
    15721 cgccactgga ataatggaaa gaatcgtcac ggtcaccagt cgaatgccgt gagattcttt
    15781 atcgcgccag ctttcccggc acagtggcca caccagcaat gttatgacca gcagattgag
    15841 gaaaataacc gcctgcccca gcacgtcatc catcagattc agcggcgaca actccgccac
    15901 cacagaccaa aagtgcagcg gcagcaatgc gaggctaatg cgtacaatct ggcgacgcca
    15961 gtggctggtc aactgcgccg gcataccaaa atggcgtatc gccacgcctt ctttttccag
    16021 caccttccag cacagcccaa agaccagcca gaacatcgcg agctttttac taaaggccca
    16081 gagcagatcg ctgatattta gctgcatggt cagcaggatc aatccaatcg cgaggataat
    16141 caggcacacc ggcagcgcgc ggatcagatc gatcagaata gcttttggcg tattgagctg
    16201 actatcgtta cgcagcgatc ccacggcggc ggccagcttc tgttgatacg cttttaacca
    16261 tttcagacgc cagcggatta aaccggcgat gagcaagagc ggcaacccgg ccaaaaaagc
    16321 aataaatact gcgggccagg ctttttgcca gttcaccgtg attttcatgg cgctgaattg
    16381 ctcttttaac gtttggggga acgctttaag ccagtcccag tccatagggc ggttactgtt
    16441 cacccaaaaa atctgctgcg tcagaatggc tttcagattt ttcgagacgc tcatcaactg
    16501 ctgctggtta acttgcaggt taatcgccat catcagctgg ttacccaact gtttatttag
    16561 ctgatccaat agctcacggc gcatctccac cacctgaagc aacgcatcat gaacttcatc
    16621 attcacctcg ctggtatgcc cctcctccag cttgtcgaca aaggcatcgc tttggaataa
    16681 ggcatcacgc tgctggttga tttcaaactg ctccagacgc aaatccgcaa tgcggttggt
    16741 catatcttcg agttcgtcgg cggagggcag ggtttgctgc tgttgataaa gaatacgcga
    16801 cagcaacagg ctgcctttta agacggcaat ctgttctttg atatttcttt ccgactgcag
    16861 agcgcgatcg agccagtttt ttactttaat gttttgctgc atcaacatat tgccgttttc
    16921 ggtcgcgaca atcagacgct ggctgagttg atggttaata tccagttcct gttttaccaa
    16981 cgggttcgcc tggatacgcg ccgtttcgtc cggcgaaata gcctcctggg ccgttttttc
    17041 cgttagcgta agtcgtttac tgttgaccgc ctcctgtaaa agttgaagct gatgttcaag
    17101 gcgattactg ttggccgtca cgtaatcccg ctgtttttgc agggtgtcct gcaaaacggt
    17161 attcccttca agactcttac gttgctggtc gatctgcgca ttaagcagcg cctgttgtgc
    17221 ctgtaataac acctgttggc tggggcgaag cgcggcttcg ccgacgttat tgccgtccag
    17281 acggttacgg atttgctgta tttgctgtga ggcggtatac atggcgtttt gcacgcgctc
    17341 cggctgggtt tgtagcgaaa caagctggct gttataagcg gcaagatcgt tttgcgagtt
    17401 ttgcaaatca tccagtacct gcgccacgcg cagctcaagc tgacgtagcg aaagcgcact
    17461 cagcgttttt cgcatttcat catcattatc gacatcgctc agcgcattca acgcagccgt
    17521 cgcctgacgc attttttcag gcgcctgcgc caccttctgc cgtagctgta cggtctcctc
    17581 ttttacccgc tcgattttct ccagcgtagc taacgtatca ataaggtctt gctggacgag
    17641 cttatcctgg gcggagagat ctttttgctt attcagcgta tccagctggt tttgcacatc
    17701 cgcttttgac ggcaggtcgc cattcgtttg cccccgggca aacgccagag actgacagga
    17761 cagcaggata ataagaacgc taattgtaat aaaaacaaaa tgctgtgaac gtttataaag
    17821 ctgcaacata gtcatgagaa tgaagtgtct gaaccggcaa gcagaccgga aataattgag
    17881 tcgcaagaat atcacgcctg taacaaacag aatagcgaca cagaaaatgt ccaggagttt
    17941 tcctggaata ttatcagggg gagccgttga ccgtcgacgc gcgcagcgtc ggacacaatt
    18001 gatacatctc cagcaggatc gtgacgtagg cgcgagcttc tttttttaaa tcaaacgatt
    18061 gcggagcaaa taaccagttt tccatgagcc ctgaaataaa gctgcgcatc agtatcgccg
    18121 cacgacgggt cagcagattt tcaggcagca ttttagcatt aatacaatgt tttaacgttt
    18181 gttcaatccg atcgtaactt tccagacaaa ggctacgttg cgcctgttga accacaacca
    18241 tttctccgac aaactcacat ttatggaata taatctccat caataagcgg cgtcgttctt
    18301 ctgttacagt agcttcaaga atatgaacta aaatttctct taatacagat agtggatcgt
    18361 cggggaattt tgcctgatac tcaatctcaa gctcaccaat attggattct gatagctccc
    18421 agatctcact gaataaatcc gacttatttt tgaaatgcca atagattgcg ccgcgcgtca
    18481 cgccagcagc gttcgcaatc tccgccagcg aggttgccga tacgccttgc tgcgagaaca
    18541 aacgcagggc cacatccagg atgtgttgtc gtgtctccag cgcttgttgt ttggtttttc
    18601 gtgccatatg tcggtgaatt tacaggcgtt agatttacat acatttatgg atgtatgtac
    18661 catagcatga cgataatata aacgcagcaa tgggtttaag gacctttgac cattgaccaa
    18721 tttgaaatcg gacactcgag gtttacatat gaacaaaaac agagggttaa cgcctctggc
    18781 ggtcgttctg atgctctcag gcagcttagc gctaacagga tgtgacgaca aacaggacca
    18841 gcaaggcggc cagcagatgc cagaagttgg ggttgtcaca ctaaaaacgg aaccactgca
    18901 aatcacaact gaacttccgg gtcgtaccgt tgcttaccgt atcgccgaag ttcgcccgca
    18961 ggtaagcggc attatcctga agcgtaattt cgttgaggga agtgatatcg aagcgggagt
    19021 ctctctctat cagattgatc ctgcgactta ccaggcgact tacgacagcg ctaagggcga
    19081 tctggcaaaa gcgcaggccg ccgcgaatat cgctgaactg acggtgaagc gttatcaaaa
    19141 gctgctgggt acgcagtaca tcagtaagca ggaatacgat caggcgctgg ctgacgcgca
    19201 acaagcgact gccgccgttg tcgcagcaaa agccgccgtt gaaaccgcac gtatcaacct
    19261 ggcgtatacc aaagtcacct caccgattag cggtcgtatt ggtaagtcgt ccgtaacgga
    19321 aggcgcgctg gtacagaacg gtcaggcgtc ggcgctggcg acagtgcagc agctggaccc
    19381 tatttatgtc gatgtgaccc agtccagcaa tgacttcctg cgcctgaagc aggagctggc
    19441 aaatggttcg ctgaagcagg aaaacggcaa agcgaaggtc gatctggtga caagcgacgg
    19501 tatcaaattc ccgcagtccg gtacgcttga attctccgac gtgaccgttg accaaagcac
    19561 cgggtctatt actttgcgcg ccatcttccc taacccggat cacaccttat tgccaggaat
    19621 gttcgttcgc gcacgtctgc aggaagggac aaaaccgacg gcattactgg ttccacaaca
    19681 gggcgttacc cgtactccac gcggcgatgc cacggtgctg gtggttggcg ctgataacaa
    19741 agtggaaacc cgccaaatcg tcgcaagcca ggcgatcggc gataagtggc tggtgactga
    19801 cgggttgaaa gcgggcgacc gcgtagtcgt cagcgggctg caaaaagtac gtcctggcgc
    19861 acaggttaaa gtgcaggaaa ttaccgcgga taacaaacag caagccgcaa gcggtgatca
    19921 acctgctcag cccaggtctt aacttaaaca ggagccgtta agacatgcct aatttcttta
    19981 tcgatcgccc tatatttgcg tgggtgatcg ccatcatcat catgttggca ggggggctcg
    20041 cgatcctcaa attgccggta gcgcaatatc cgacgattgc gccaccagca gtgacgatct
    20101 ccgcaaccta ccctggcgct gatgcgaaaa cggtacagga taccgtcacg caggttatcg
    20161 aacagaatat gaacggtatc gataacctga tgtatatgtc ctccaacagt gactccacgg
    20221 ggaccgtaca gatcacgctg acctttgaat ccggcaccga tgcggatatc gcgcaggttc
    20281 aggttcagaa caagttgcaa ctggcaatgc cgttacttcc ccaggaagta cagcaacagg
    20341 gcgtgagcgt tgagaagtcc tcaagtagct tcctgatggt agtgggcgtc attaacaccg
    20401 acggcaccat gacccaggag gatatttcgg attacgttgc cgccaatatg aaagatccga
    20461 tcagccgtac ctctggggtg ggcgacgtcc agctgtttgg ttcgcagtat gcgatgcgta
    20521 tctggatgaa tccgacagag ctgaccaaat accaactgac gccggtcgac gtgattaacg
    20581 cgatcaaagc gcagaacgcc caggtcgcgg caggtcagct cggtggtaca ccgccggtaa
    20641 aaggccagca gcttaacgca tcgattattg cccaaacgcg tctgacctca acggatgagt
    20701 ttggcaaaat cctgctgaaa gtgaatcagg atggctctca ggttcgtctg cgggatgtag
    20761 cgaaaattga gcttggcggc gaaaactacg acgtcatcgc gaaatttaac ggtcagccag
    20821 cgtcaggtct tggcatcaaa ctggctaccg gcgccaacgc gctggatacc gctaccgcta
    20881 ttcgcgccga actgaaaaaa atggaaccgt tcttcccgcc agggatgaaa atcgtctacc
    20941 cgtatgacac cacgccgttc gtgaagatct ctattcatga agtggtaaaa acgctggtcg
    21001 aagcgattat cctcgtgttc ttggtgatgt acctgttcct gcagaacttc cgcgcgacgt
    21061 tgattccgac tattgcggtt ccggtggtgt tgttgggaac ctttgccgtg cttgcggcat
    21121 tcggtttctc gataaacacg ctgacgatgt tcgggatggt gctcgccatc ggcttgctgg
    21181 tggatgacgc catcgtggtg gtcgagaacg tcgaacgtgt tatgacggaa gaaggccttc
    21241 cgccgaagga agcgacgcgc aaatccatgg gccagattca gggcgcattg gtgggtatcg
    21301 cgatggtact gtcggcggta tttattccga tggccttctt tggcggctca accggggcaa
    21361 tttatcgtca gttctctatc accatcgtat cggcgatggc gctgtcggtg ctggtcgcgc
    21421 tgatcctgac gcccgcgctg tgcgcgacga tgctcaaacc cgtcgccaaa ggcgatcatg
    21481 gcgaagggaa aaaaggcttt ttcggctggt ttaaccgcct gtttgataag agcacgcatc
    21541 actacaccga tagcgtaggg aatattctgc gcagcaccgg gcgttatctg ctgctctatc
    21601 tcattatcgt cgtcggtatg gcttatctgt tcgttcgtct gccaagctct ttcttgccgg
    21661 atgaagacca gggcgtattc ctgacaatgg tccagctccc cgccggcgcg acgcaagagc
    21721 gcacgcaaaa agtgctggat gaggtcacgg attactatct gaacaaagag aaagccaacg
    21781 ttgaatcggt attcgccgtc aacggcttcg gttttgcagg gcgcggtcag aataccggta
    21841 ttgcatttgt gtcgttgaaa gactgggccg atcgtccagg cgaaaaaaac aaggttgaag
    21901 cgattaccca gcgggcaacc gcagcgtttt cacaaattaa agatgcgatg gtcttcgcct
    21961 ttaacctacc ggcgattgtt gaactgggca ccgcaaccgg gtttgacttc gagttgattg
    22021 accaggcggg acttggtcac gaaaaactca cccaggcacg taatcagttg ttcggcgagg
    22081 tggcgaaata tcctgatctg ttggtcggcg ttcgacctaa cggtctggaa gatacgccgc
    22141 agtttaaaat cgatatcgac caggaaaaag ctcaggcgct gggcgtgtct attagcgaca
    22201 ttaataccac gctgggcgca gcatggggcg gcagctatgt aaacgacttt atcgatcgcg
    22261 gtcgtgtgaa gaaagtttac gtgatgtccg aagcgaaata ccgcatgttg ccggatgata
    22321 ttaacgactg gtacgttcgt ggtagcgatg gtcagatggt gccgttctcc gcattctcct
    22381 cttcccgctg ggaatatggt tcgccgcgtc tggaacgcta taacggtctg ccttcgatgg
    22441 aaattctggg tcaggcggcg ccaggcaaga gtactggtga agcgatggcg atgatggaag
    22501 aactggccag caagctgccg tcaggcattg ggtatgactg gaccgggatg tcctaccagg
    22561 agcggttgtc cggcaaccag gcccctgccc tgtatgctat ctcgctaatc gtcgtcttcc
    22621 tgtgtctggc ggcattgtat gagagctggt ctatcccgtt ctccgtaatg ctggttgttc
    22681 cgcttggggt tatcggcgcg ctgctggccg cgaccttccg cggactgact aacgacgttt
    22741 acttccaggt gggcctgctc acaaccattg ggttgtcggc gaagaacgcg atacttatcg
    22801 tcgaattcgc caaagactta atggataaag aagggaaagg tctggtagaa gcgatgctgg
    22861 aggccgtccg gatgcgtttg cgtccgattc tgatgacctc gttagcgttc atgctggggg
    22921 ttatgccgct ggttatcagt tccggcgcgg gttccggcgc gcagaatgcg gtaggtactg
    22981 gcgtactggg cgggatggta acggcaaccg tactggctat tttcttcgta ccagtcttct
    23041 tcgtggtggt acgccgccgc tttagccgta aaagcgaaga tattgagcat agtcattcga
    23101 cagaacatcg ctgatttgct cactgttgat aaggccgcgc aagcggcctt ttt
//
LOCUS       DAJVKX010000065        23044 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000065 DAJVKX010000000
VERSION     DAJVKX010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23044
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.065"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            64..2244
                     /gene="katG"
                     /locus_tag="OPY25_002613"
     CDS             64..2244
                     /gene="katG"
                     /locus_tag="OPY25_002613"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HCS0928201.1"
                     /translation="MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAA
                     AASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDI
                     INLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWEVNAVAAR
                     VLPVLEALQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDI
                     EMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFD
                     GSQNGVFTDRPGVLSTDFFANLLDMRYEWKPTDDANELFEGRDRLTGEVKYTATRADL
                     VFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(2351..3454)
                     /locus_tag="OPY25_002614"
     CDS             complement(2351..3454)
                     /locus_tag="OPY25_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HCS0928202.1"
                     /translation="MDRIIQSPGKYIQGANVIARLGDYLKPMANNWLVVGDKFVLGFA
                     EETLRKSLTDAGLSVEIAPFGGECSQNEIDRLRAVAEKSQCGAVLGIGGGKTLDTAKA
                     LAHFMNVPVAIAPTIASTDAPCSALSVIYTDAGEFDRYLLLPHNPNMVIVDTQIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLIEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAIHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENASVEEIETVAALCHSVGLPITLAQLDIKQDIPAKMRIVAEASCAEGE
                     TIHNMPGGATPDEVYAALLVADQYGQRFLQEWE"
     gene            complement(3466..4128)
                     /gene="fsa"
                     /locus_tag="OPY25_002615"
     CDS             complement(3466..4128)
                     /gene="fsa"
                     /locus_tag="OPY25_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCS0928203.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIVAASKESIWDVLP
                     RLQNAIGEEGTLFAQTMSRDAKGMVEEAKRLNNAIPGIVVKIPVTAEGLAAIKLLKKE
                     GIVTLGTAVYSASQGLLAALAGAKYVAPYVNRVDAQGGDGIRMVLELQTLLEHHAPDS
                     MVLAASFKTPRQALDCLLAGCQAITLPLDVAQQMLNTPAVESAIEKFEQDWKNAFGNL
                     NL"
     gene            complement(4383..5219)
                     /locus_tag="OPY25_002616"
     CDS             complement(4383..5219)
                     /locus_tag="OPY25_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0928204.1"
                     /translation="MYHDVSHLLSRLINGPLPLRQIYFASASGPAPELAYQVDFPRLE
                     IVLEGELTDMSITAPLIPCDVLYVPAGGWNIPQWQTPVTTLSILFGKQQLGFSVVYWD
                     GQQHQNLTKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSRALFEAIREYIDERYAAPLTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHRCGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EK"
     gene            complement(5380..7113)
                     /locus_tag="OPY25_002617"
     CDS             complement(5380..7113)
                     /locus_tag="OPY25_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HCS0928205.1"
                     /translation="MQSTLLQTKPAFSWKALGWALLYFWFFSTLLQAIIYLTGYSGTN
                     GLRDSLLYSSLWLIPVFLFPGRIRVIAAVIGVVLWAASLAALSYYVIYGQEFSQSVLF
                     VMFETNANEASEYLSQYFSLKIVLVALAYTVAAILLWTRLRPVYIPSPWRYLVSFALL
                     YGLILHPIAMNTFIKHKSMEKTLDSLASRMEPAAPWQFITGYYQYRLQLASLNKLLNE
                     NDALPPLANFQDHSGDAPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPGLT
                     VFNNVVTSRPYTIEILQQALTFADEKNPDWYLTKPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSKQTDKQFYMNQQRTQSAREYDSNVLAPFKAVLADPAPKKFIIVHLLGT
                     HIKYKFRYPENQGKFDGKTDHVPPGLSSDELESYNDYDNANLYNDYVVASLIKDYKAT
                     DPNGFLLYFSDHGEEVYDTPPHKTQGRNEDSPTRHMYTVPFLLWTSEKWQAAHPRDFS
                     QDVDRKYSSSELIHTWSDLAGLTYDGYDPTRSITNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            complement(7315..9966)
                     /gene="ppc"
                     /locus_tag="OPY25_002618"
     CDS             complement(7315..9966)
                     /gene="ppc"
                     /locus_tag="OPY25_002618"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HCS0928206.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILDRVETIRKLSKS
                     SRAGNEANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIAHTLRKLKNQPDLNDATIKKAVESLSLELVLTAHPTEITRRTLIHKMGEINNCLKQ
                     LDNTDIADYERHQVMRRLRQLIAQSWHTDEIRKQRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVDFVPVRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKAT
                     DLFLKDIHVLVSELSMVDATPELLALVGEEGASEPYRYLMKKLRARLMATQSWLEARL
                     KGEKLPKPAGLLTQNEQLWEPLYACYQSLQACGMGIIANGELLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGEITRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWEPSND
                     TREVLETCKVIAEAPKGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNADDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EVTVSSLSLYTSAILEANLLPPPEPKDSWRHIMDELSVISCETYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFSKADLWLADYYDQRLVAKTLWPLGKEL
                     RDLLEEDIKVVLAIANDSHLMADLPWIAESIQLRNVYTDPLNVLQAELLYRSRLTEEQ
                     GKSPDPRVEQALMVTIAGVAAGMRNTG"
     gene            complement(10335..11486)
                     /gene="argE"
                     /locus_tag="OPY25_002619"
     CDS             complement(10335..11486)
                     /gene="argE"
                     /locus_tag="OPY25_002619"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HCS0928207.1"
                     /translation="MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFS
                     DLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHD
                     NKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTAL
                     RPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQ
                     LRDSLKARYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNG
                     LLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEA
                     PFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH"
     gene            11575..12579
                     /gene="argC"
                     /locus_tag="OPY25_002620"
     CDS             11575..12579
                     /gene="argC"
                     /locus_tag="OPY25_002620"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HCS0928208.1"
                     /translation="MLNTLIVGASGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDVRDFSADVDVVFLATAHEVSHDLAPQFLQAGCVVFDL
                     SGAFRVNDRAFYEKYYGFTHQYPELLEQAVYGLAEWNADKLNTANLIAVPGCYPTAAQ
                     LSLKPLIDGGLLDLTQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     AAHLGAEVIFTPHLGNFPRGILETITCRLKAGVTHAQVADVLQKAYGDKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIVVATEDNLLKGAAAQAVQCANIRFGFAETQSLI
                     "
     gene            12587..13363
                     /gene="argB"
                     /locus_tag="OPY25_002621"
     CDS             12587..13363
                     /gene="argB"
                     /locus_tag="OPY25_002621"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463002.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HCS0928209.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGL
                     FLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKV
                     NAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA"
     gene            13481..14857
                     /gene="argH"
                     /locus_tag="OPY25_002622"
     CDS             13481..14857
                     /gene="argH"
                     /locus_tag="OPY25_002622"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HCS0928210.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTADEQRQLEEALNVLLEEVRANPQQILQSDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKETVMELLTANRQLQSALVETAQANQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     TSATRNSLDSVSDRDHVLELLSDAAIGMVHLSRFAEDLIFFNSGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDI
                     WLDCLHMAALVLDGIQVKRPRCQDAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEALPLADLQKFSRVIGDDVYPILSLQSCLDKRAAKGGVSPQQVAQAID
                     DAKVRLAL"
     gene            15141..16058
                     /gene="oxyR"
                     /locus_tag="OPY25_002623"
     CDS             15141..16058
                     /gene="oxyR"
                     /locus_tag="OPY25_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HCS0928211.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGLLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTIG
                     PYLLPLIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCAILALVKESEAFIEVPL
                     FDEPMMLAIYEDHPWANRDRVPMSDLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPQERKRDGVVYLPCIKPEPRRTVGLVYRPGS
                     PLRSRYEQLAEAIRGAMDGHFDKALKQAV"
     gene            complement(16041..17441)
                     /gene="sthA"
                     /locus_tag="OPY25_002624"
     CDS             complement(16041..17441)
                     /gene="sthA"
                     /locus_tag="OPY25_002624"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HCS0928212.1"
                     /translation="MPHSWDYDAVVIGSGPGGEGAAMGLVKQGARVAVIERYHNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNAHFIDEHTLALECHDGTVETLTAEKFVIACGSRPYHPNDVDFSH
                     PRIYDSDSILSLHHEPRHVIIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALENIGLETDSRGQLKVNSMYQTALPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            17640..18275
                     /gene="fabR"
                     /locus_tag="OPY25_002625"
     CDS             17640..18275
                     /gene="fabR"
                     /locus_tag="OPY25_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463006.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HCS0928213.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDIGAEQRRQLEERLVLQLRMIAKGAYYWYRREQEKIAHHSE"
     gene            18291..18650
                     /locus_tag="OPY25_002626"
     CDS             18291..18650
                     /locus_tag="OPY25_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HCS0928214.1"
                     /translation="MKQSGQDKGTLLLALIAGLSINGTFAALFSAIVPFSVFPVISLV
                     LTVYCLHQRYQNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIL
                     VFWIGFKLRNRKQDTAE"
     gene            complement(18697..19797)
                     /gene="trmA"
                     /locus_tag="OPY25_002627"
     CDS             complement(18697..19797)
                     /gene="trmA"
                     /locus_tag="OPY25_002627"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HCS0928215.1"
                     /translation="MTPEHLPTEQYEAQLAEKVARLQSMMAPFSGLVPEVFRSPVSHY
                     RMRAEFRLWHDGDNLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEIIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELY
                     CGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHTVSRLALFDQFPYTHHMECGVLLTAR"
     regulatory      19912..20105
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20171..22015
                     /gene="btuB"
                     /locus_tag="OPY25_002628"
     CDS             20171..22015
                     /gene="btuB"
                     /locus_tag="OPY25_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HCS0928216.1"
                     /translation="MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLA
                     PVTIVTRQDIERWQSTSVNDVLRRLPGVDIAQSGGTGQNSSIFIRGTNSSHVLVLIDG
                     VRLNLAGVSGSADLSQFPVSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTEL
                     TAGWGSNSYQNYDLSTQQQLGENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFL
                     SKTLYGALEHTFSDRWSGFVRGYGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRF
                     NGERIQSQLVSSYSHSKDYNYDPHYGRYDTSATLDEMKQYNVQWTNSVVVGHGNVGAG
                     VDWQKQTTTPGTGYVPEGYDQRNTGVYLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGYYGNPNLNPEKSKQWEGAFEGLTAGVS
                     WRISGYRNDINDMIDYDDHLQKYYNEGKARIKGIEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLPRRSKQMAKYQLDWDVYDFDWGVTYQYLGSRYDSDYSAYPYRTVKMGGVSL
                     WDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     gene            21960..22811
                     /gene="murI"
                     /locus_tag="OPY25_002629"
     CDS             21960..22811
                     /gene="murI"
                     /locus_tag="OPY25_002629"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCS0928217.1"
                     /translation="MATKLQDENTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRRLL
                     PDLHYIYAFDNVAFPYGEKSETFIVERVVEIVTAVQQRYPLSLAVIACNTASTVSLPA
                     LREKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPYTHELIARFANECQIAML
                     GSAELVELAEAKLHGDSVSLEELRRILRPWLRMPEPPDTVVLGCTHFPLLRDELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGAEQLLPVLQRYGFE
                     TLEKLAV"
BASE COUNT         5137 a         5965 c         6520 g         5422 t
ORIGIN      
        1 caactatatc tatttgctcc tggtgtatat cgtaacggta acactttaaa agggagctga
       61 gatatgagca cgaccgacga tacccataac acgttatcca ctggaaaatg tcctttccat
      121 cagggggggc atgaccgaag cgcaggcgca gggactgcca gccgcgactg gtggccgaac
      181 cagcttcgtg tggatctttt gaatcaacat tccaaccgtt ctaacccgct gggcgaagac
      241 tttgactacc gcaaagagtt tagcaagtta gactactccg ccctgaaagg ggatctcaag
      301 gcgctgctga ccgattcaca accgtggtgg cccgccgact ggggcagcta tgtcggtttg
      361 tttattcgta tggcctggca tggcgctggc acctaccgtt ctattgatgg tcgtggcggc
      421 gcgggtcgtg gtcaacagcg ttttgcgccg cttaactcct ggccggataa cgtcagcctg
      481 gataaggcgc gtcgtttgtt gtggccgatt aagcagaaat atggccagaa aatttcctgg
      541 gccgacctgt ttattctggc gggtaacgtg gcgctggaaa actccggctt ccgtaccttc
      601 ggtttcggcg ccgggcgtga agatgtctgg gaaccggatc tggatgtgaa ctggggcgat
      661 gaaaaagcct ggttgactca ccgacaccct gaagcgctgg caaaagcgcc gctgggcgcg
      721 accgagatgg gccttatcta cgttaacccg gaggggccgg atcacagcgg cgaaccactt
      781 tctgccgccg ccgctattcg cgctaccttt ggcaatatgg ggatgaacga cgaagagacc
      841 gtggcgttga tcgctggcgg gcataccctc ggtaaaaccc acggcgcggc agcagcatcc
      901 catgtagggg ccgatccgga agccgcgccg attgaagcgc agggcttagg ttgggccagc
      961 agctatggta gcggcgttgg cgcggatgct attacctccg ggctggaagt ggtctggacg
     1021 cagacgccga cccagtggag caactatttc ttcgagaacc tgttcaaata tgagtgggta
     1081 caaacccgta gtccggctgg cgctatccag tttgaagcgg tagacgcgcc ggatatcatc
     1141 ccggacccgt tcgatccgtc gaaaaaacgt aagccaacca tgctggtcac cgacctgacg
     1201 ctgcgttttg atccggagtt cgagaagatt tcccgtcgtt tccttaacga tccacaggcc
     1261 tttaatgaag cctttgctcg tgcctggttc aaactgacgc acagagatat gggaccaaaa
     1321 gcgcgttaca tcggaccgga agtgccgaaa gaagatctga tctggcagga cccgttgccg
     1381 caaccgctct accagccaac gcaggaagac attatcaacc tgaaagcggc gatcgctgca
     1441 tccgggcttt ctattagcga gatggtttcg gttgcctggg catccgcgtc tactttccgc
     1501 ggcggcgata agcgtggcgg cgctaacggc gcgcgtctgg cattagcgcc tcagcgcgac
     1561 tgggaggtca acgccgttgc ggctcgcgtt ctgccggtat tagaagcgct ccagaaaacg
     1621 acgaataaag cctcgctggc cgatattatt gtgctggcgg gcgtggtcgg tatcgagcag
     1681 gcggccgctg ctgcgggtgt cagcatcagc gtaccttttg cgccgggccg ggtggatgcg
     1741 cgtcaggatc agaccgacat cgagatgttc tcgctgcttg aaccgattgc cgatggattc
     1801 cgtaactatc gtgcgcgtct ggatgtgtcg acgaccgaat cgctgttgat tgataaagcg
     1861 cagcagttaa cgttgaccgc gccggaaatg acggtactgg ttggcgggat gcgtgtgctg
     1921 ggaaccaact ttgacggcag ccagaacggt gtctttaccg acagaccggg cgtgctcagc
     1981 actgacttct tcgctaatct gctggatatg cgttacgagt ggaagcccac cgacgacgct
     2041 aatgagctgt tcgaaggccg ggatcgcctg actggcgagg taaaatacac ggcaacccgc
     2101 gccgatctgg tgtttggttc caactccgta ctgcgcgcgc tggcggaagt ttacgcgtgt
     2161 agcgatgcgc acgagaagtt tgtgaaggac ttcgtcgcgg catgggtgaa agtgatgaac
     2221 ctggaccgtt tcgatctgtt gtaaatctta tgccggatga cgctaacgct tatccggcct
     2281 accgtctcat atgcccaccg ggcaaaaaaa tccccgcgca attgcgggga tttttcattg
     2341 caagccgacc ttattcccat tcctgcaaga agcgttgacc gtactggtcg gcgaccagca
     2401 gcgcggcgta cacttcatcc ggcgttgcgc cgccaggcat gttatgaata gtttcacctt
     2461 ctgcgcagga ggcttccgcg acgatgcgca ttttggccgg gatatcctgc ttaatatcca
     2521 gttgcgccag cgtaatcggc aggccaacgg aatggcacag cgcagcaacg gtttcgattt
     2581 cttcgaccga cgcgttttcc agcaccagtt gcgtcagcgt accgaaagcg accttctccc
     2641 cgtgataata gtggtgcgca tccggaatcg ccgttaaacc gttatgaatc gcgtgcgctg
     2701 cggccagacc gccgctttca aaaccgaccc cgctcaggta ggtgttggct tcgatgacac
     2761 gttccagcgc tggcgtgacg acgtgctgtt cggcggccaa catggctttt tcgccttctt
     2821 cgatcagcgt gttatagcat agctccgcca gggccagcgc ggcctgtgta cacttgccgc
     2881 ccgccattgt ggtggcgccg ctgcgtgagc aggcgcgcgc ttcaaaccag gtcgccagcg
     2941 catcgccgat accggctgcc agcagacgcg ccggcgcgcc cgccactatc tgcgtatcga
     3001 caatgaccat attcgggtta tgcggcagca gcagataacg gtcaaactca ccggcatcgg
     3061 tataaataac cgagagtgcg ctgcacggtg cgtcggtaga ggcgatggtc ggcgcgatag
     3121 cgaccgggac gttcataaag tgcgccagcg ctttggcggt atccagcgtt ttaccgccgc
     3181 cgatacccag tacggcgcca cactgacttt tttcggcgac ggcgcgcagc ctgtcgatct
     3241 cattttgcga acattcgccg ccaaacgggg cgatttctac tgacaaaccg gcatccgtca
     3301 ggcttttgcg cagcgtctct tcggcaaatc ccagcacgaa tttatcgccc acaaccagcc
     3361 agttgttcgc cattggtttt aaataatcgc caagacgcgc gatgacgttt gcaccctgaa
     3421 tatacttacc tggtgactga ataatgcgat ccatacattt ctctcctaca ggttcagatt
     3481 accaaaagcg tttttccagt cttgctcaaa cttctctatt gctgactcta ccgcaggcgt
     3541 attgagcatt tgttgcgcta catctaaagg aagggtaatc gcctggcaac ctgccagtaa
     3601 gcaatccagc gcctgccgcg gcgttttaaa gctggccgcc agtaccatgc tgtcgggcgc
     3661 gtgatgttcc agtagcgttt gcagctccag aaccatacga atgccatcgc cgccctgcgc
     3721 atcaacgcgg ttgacgtagg gagcgacata ttttgcgccc gccagcgccg ccagcaggcc
     3781 ctgcgacgcg ctgtagacgg cggtgcccag cgtcacgatg ccttcttttt tcagcaattt
     3841 aatcgctgca aggccttcgg cggttaccgg aattttaacc acaatgccgg ggatggcgtt
     3901 attcagccgt ttggcttctt ccaccatccc tttcgcgtcg cggctcatgg tctgcgcaaa
     3961 taaagtgcct tcttcgccga tggcgttttg cagcctgggc agcacatccc agatagattc
     4021 tttgctggct gccacaatgc ttggattggt ggtgacgccg gcaatcggga aaatgcgcgc
     4081 cagacgttca acttccgcca cgttagcggt atccagatag agttccatag tctttctctt
     4141 cgtgagtttt cgttatggac aggataaagg agcgtgcccc ggatgcgcta tgtgacaaat
     4201 ctgccaaaaa ctggacaaat gtgatgctct tggtaaagtg tgatttactt cacaagttgg
     4261 tgatgattaa cgtataacgt gctgttgtat gccatgtggg ggagtgaggt ttttgcattg
     4321 atattacaat aatccagtaa atgcgcgttt tatctactgt attctcttta ttggcgtgtg
     4381 gattatttct ccgttagctg gctgtgatac tggcggcgat actccgaagg cgaacgttcc
     4441 gtatttttgc gaaacaggcg gcagaaatag ttactgtcga caaagccgca gcggtgcgcc
     4501 acctctttca ctttcaggtc atagcccttc agcaacgttt tggcgtgttc cagtcgcgta
     4561 tggttcaggt attcgttaaa gccgatggct cccgttttct ggaacaggtg cgagaggtaa
     4621 tttggcgaga tataaaacgc ctgtgctacc gattcgcgcg tcaacggcgc ggcgtagcgt
     4681 tcatcaatat actcccgaat ggcttcaaaa agcgcacggc tacgggaggc ggtctggatt
     4741 tggctgccga gcagatcgcg gcaatggctt agtaggctgg cgacaatcaa tctggccgtt
     4801 tgctgctctt gcggctgcat ctgcatctca ttaagcgttt gtaacaggaa cgagccgata
     4861 cgcgggccac ggcgcgcaac gtgctgtttc gtgaggtttt gatgctgctg accgtcccag
     4921 tagaccacgc tgaaacctaa ctgctgtttg ccaaacagaa tgctcagggt ggtgacgggc
     4981 gtttgccact gcgggatgtt ccagccgcca gccggaacgt agagaacatc gcaaggaatg
     5041 agcggggcgg taatgctcat gtcagtaagc tcgccctcca gcacaatctc cagccgcgga
     5101 aaatccacct ggtacgccag ttccggcgct gggccgctgg cgctggcaaa ataaatctgg
     5161 cgcagcggca gcgggccgtt gatgagacgg gagagaaggt ggctgacgtc gtgatacatg
     5221 ataatcccct gccgatcgca aacagaggaa acagtaacgt cgaaaaccga tgtcctcaag
     5281 caattattgc cggatagcgg cgctttgcgc cttatccgga ctacgggaga gaagaacgcc
     5341 aggcccgata agcgttagcg ttatcgggca acatacaggc tattgattac cgacctgatc
     5401 gccatacggc aacgtatcat aatcaatcag cgcgtttttc ttatacgggt tgccaatcca
     5461 gcgcgtggtc tctttgaact gcgggttggt gatggaacgc gtcgggtcgt aaccatcata
     5521 ggtcaggccc gctaagtccg accaggtatg gataagctcg gaactgctgt acttacgatc
     5581 gacatcctgt gagaagtcgc gcggatgcgc cgcctgccat ttctctgagg tccacagcag
     5641 gaacggcacc gtatacatat gacgggttgg cgaatcttcg tttcgtccct gcgtcttatg
     5701 cggcggcgtg tcatacactt cttcaccgtg gtcggagaag tagagcagga aaccgttcgg
     5761 atcggtcgct ttatagtcct taatcaggct ggcgacaaca tagtcgttat acaggttcgc
     5821 gttgtcgtaa tcgttatacg attccagttc gtcgctgctt aatcccggcg gaacatggtc
     5881 ggttttacca tcaaacttgc cctggttttc tggatagcgg aacttgtatt taatgtgcgt
     5941 tcccagcaga tgcacaataa tgaatttttt cggcgccggg tcggctaaca ccgctttaaa
     6001 cggcgccagc acgttgctgt catattcgcg cgcgctttga gtgcgctgct ggttcatata
     6061 gaactgctta tcagtctgct tagagaacac ggtcagcatg gtattacgcg ccgtcatcgt
     6121 ctgctggtta gtgatccaga aggttttata cccggcctgt ttcatcatat tcatcagcga
     6181 tggcttcgtc agataccagt ccgggttctt ttcgtccgcg aacgttagcg cctgttgcag
     6241 gatctcaatg gtgtacggtc gcgaagttac cacattatta aacacggtca gcccggggtc
     6301 ggttttatgc agcgcgtcca gttccggcgt ggtttcgcgc ggataaccgt acagactcat
     6361 acggccacgc tgggtcgatt cgccaatcac cagtaccagt gtgcgcggcg catcgccgga
     6421 gtggtcctgg aagttagcca gcggcggcag ggcatcgttt tcattcagca gtttattcag
     6481 cgaggcgagc tgtaaacggt actgatagta gccagtaata aattgccacg gagcggcggg
     6541 ttccattcgt gacgccaggc tatccagcgt tttctccatc gacttatgct tgataaaggt
     6601 attcatcgcg atgggatgga ggatcagccc gtacagcagg gcaaacgaca ccagataacg
     6661 ccagggggat ggaatataaa ccgggcgcag acgtgtccac agcaaaatcg ccgccaccgt
     6721 ataagccagc gcgacaagaa caattttcag actgaaatat tggcttaaat attcgctggc
     6781 ttcattggcg ttggtttcaa acatcacaaa cagcacgctt tgcgagaact cctgcccgta
     6841 gattacgtaa tagctcagcg ccgccagcga ggcggcccag agtacgacgc caataacggc
     6901 agcaataacc cggatgcggc ctggaaacaa aaagaccggg atcagccata gtgagctgta
     6961 cagtagcgaa tcccgcagac cgtttgtccc actgtatccg gtgagataaa taatggcctg
     7021 caggagggtg gaaaagaacc aaaagtagag cagtgcccag cccagggctt tccagctaaa
     7081 cgcgggttta gtctggagta atgtggattg cataatgaga gcctgtcttt aatcgtagcg
     7141 ccaaacgtaa cgcctgaacc ttaaaagaat ctgaagcaaa cctgctttat gccgcacgtt
     7201 ttgctaagaa agatttataa atgcagacag gaatatattg aaaaaatgac gaggatgaca
     7261 gcagtatttc atgccgcccc cacataactg cgtgagggcg gctttctttt ggcgttagcc
     7321 ggtgttgcgc ataccggcgg cgacgcccgc aatcgtgacc atcaacgcct gttcgacgcg
     7381 aggatcgggc gatttgccct gctcttcagt cagacgggaa cgatacagca attcggcctg
     7441 caacacgttt aatggatcgg tataaacgtt tcttaactga atggactccg caatccacgg
     7501 taagtcggcc atcaggtgcg aatcgttggc aatcgccagc accactttaa tgtcttcttc
     7561 cagtaggtct cgtagctctt tgcccagcgg ccaaagcgtt ttcgccacca ggcgctgatc
     7621 gtaatagtcg gccagccaca ggtcggcttt cgagaacacc atttccagca tcccaagacg
     7681 cgtggagaag aacggccagt cgcggcacat ggcttccagt tcgctttgtt taccgtcttc
     7741 caccactttt tgcagcgcag tacccgcgcc cagccaggct ggcagcatca ggcggttttg
     7801 cgtccaggcg aagatccacg gaatcgcgcg cagcgattcg acgccgccag ttggacgacg
     7861 tttcgccgga cgtgagccga gcggcaattt gcccagctct tgttccggcg tcgcggagcg
     7921 gaagtacggt acaaagtctt tattttcgcg cacgtaaccg cggtaggttt cacaggagat
     7981 gacggaaagc tcatccataa tatgacgcca gctgtctttc ggttccggcg gcggcagcag
     8041 gtttgcttcc agaattgcgc tggtgtagag cgagaggctg ctgacggtga cttccggcag
     8101 gccgtatttg aagcggatca tctcgccctg ctcggtcacg cgcagaccgc ctttcagact
     8161 gcctggcggt tgcgaaagca gcgccgcgtg ggctggcgcg ccgccacggc caatagagcc
     8221 gccgcggccg tggaagagag tgagctcgat gccggctttt tcacaggttt tgatcagggc
     8281 gtcctgcgcc tgatactgcg cccatgacgc ggccataacg ccggcgtctt ttgccgagtc
     8341 ggagtagccg atcatgacca tctgcttacc ctgaatcagc ccgcgatacc agtcgatatt
     8401 caacaactgg gtcatcacgt cgtcggcatt gttcaggtcg tcgagggttt caaacagcgg
     8461 tgcgaccggc atggcaaagc cgatacctgc ctctttcagc agcaaatgca cagccagcac
     8521 atcagacggc gttttcgcca tagaaatcac gtaggcggcg atcgaccctt ttggcgcttc
     8581 ggcaataacc ttgcaggttt caagcacttc gcgggtatcg ttgctcggct cccagttacg
     8641 cggcagcagc ggacgtttgg agttcagctc gcggatcagg aaggcctgct tgtcggcttc
     8701 cgaccagctt tcgtagtcgc caataccgag gtagcgggta atttcgccca gcgcttcggt
     8761 atggcgggtg ctctcctgac ggatatcaat acgcaccagc ggtacgccga aacacttcac
     8821 gcggcggagc gtgtcgagta actcgccgtt ggcgataatg cccatgccac aggcctgtaa
     8881 cgactggtag caggcgtaca gaggttccca gagctgctcg ttttgcgtca gcaggccagc
     8941 cggtttgggc agcttctcgc ctttcagacg cgcttccagc caggactggg tcgccatcag
     9001 acgggcgcgc aattttttca tcaggtagcg atacggctca gacgcgcctt cttcgcccac
     9061 taacgccagc agctccggcg tggcgtcgac catcgacagt tctgatacca ggacatgaat
     9121 gtctttcagg aacagatcgg tggctttcca gcggcttaac aagagtacgt ggcgggtgat
     9181 ctccgccgtc acgttcgggt tgccgtctcg gtcgccgccc atccaggagg taaaacgtac
     9241 cggcacaaaa tccaccggca atttgtagcc gagattttct tccagttgtt cattcagttc
     9301 acgcagatag ttaggtacgc cctgccacag gctgttctca accacggcga agccccattt
     9361 ggcttcatcc accgggcttg ggcgctgctt gcggatctca tccgtatgcc aggattgggc
     9421 aatcaactgg cgcaggcgac gcatcacctg gtggcgttcg tagtcggcga tatcggtatt
     9481 atcaagctgt ttcagacagt tattgatttc ccccatcttg tgaataagcg tacggcgggt
     9541 aatttctgtc gggtgggcgg ttagcaccaa ctccaaagac agcgactcta ccgctttttt
     9601 gatggttgcg tcgttgaggt ccggttggtt tttcagttta cgcagagtgt gggcaatcac
     9661 ttccgggttg ctggcggctt cgccttttgg cgaaatgctg tggtattgct cggcagtatt
     9721 ggccaggttc aggaactgac taaacgcgcg cgcaactggc agcagctcgt cattagacaa
     9781 attttgtagc gtggtgagca gctcctggcg attagcttca ttgccggcgc gtgaagattt
     9841 ggatagctta cggattgttt ctacgcgatc aagaatgtgc tctcccagcg catccttgat
     9901 ggtttctccc agcaccttgc cgagcatact gacattacta cgcaacgcgg aatattgttc
     9961 gttcatatga ccccagacac cccatcttta atgtaattgc cctgtctctt tcatgccaca
    10021 gcggcagtgg ctgcgctcgc ccgtatgcta gttctgcgga atgggctcgt ttgccgcctt
    10081 gctgtgacgt gaaatttttc tgactttgct ttttagccgt cttttataaa gccacgtaaa
    10141 acccgtggcg tcaattactg cgaaatcggt tcagcaaacg aaaaaatggc ggtaatttat
    10201 taaagttaat tcgcatcgtg ccaaataaga aatgcttatg aacatgtggc gtagagatgc
    10261 cggatggcgc tgcgcttatg cggcctacaa gacgggggag gcccggtaaa catcgtgtca
    10321 ccgggcaata tgcattaatg ccagcaaaaa tggtgtacta cctgggtaat caattcccgg
    10381 gttggcttaa taaaacgcgt ttcgagatat tcatccggct gatgcgcctg attaattgag
    10441 cccggaccaa gcaccagcgt tgggcataat gtctgcataa acggcgcttc agtacagtag
    10501 ttcaccacgt cggtttttgt tcccaacagt ttttctacta cttcaaccag ttggtggtcc
    10561 ggtggacact cgtaacctgg aatcggcgga tgtaattccg ccaccgtcag gcggcccggc
    10621 cagcgttcgc ttaccggagc cagcgcgtcg ttaagcagtc cattaaggtc gtttaacgtc
    10681 atgcccggca gtggacgaat atccatatgc aattcgcagc aggcgcagat acggtttgag
    10741 gcatcgccgc cgtggatatg gcccagattc agcgttggat acggaacggt aaacgcctcg
    10801 tagtgatacc gcgctttcag cgagtcacgc agttgcatga tatggccaat cgcatcgtgc
    10861 atcagttcaa tggcgttaac cccacgcgcc gggtcgctgg aatgaccgga ctgccccagg
    10921 acgcgaacga cattagagat atgccctttg tgcgcgcgta tcggttgcaa cgacgtcggt
    10981 tcgccaatga tcgcgcagtc cggacgtaat gccgtggttt cggaaaaata acgcgccccc
    11041 gccatgctgg tctcttcatc ggcggtcgcc agaatgtaga gcggcttttt caactttgtg
    11101 acgtcaacgt cacgtagcgc gtccagaata aaagcgaaga agcctttcat atccgcagtg
    11161 cccagaccat agagcttatt gtcgtgctcg gtcagcgtga acgggtcgcg cgtccagcgt
    11221 ccgtcatcaa agggaactgt gtcggtatgg ccggtcagca gcaaaccgcc cgcgccatgt
    11281 ccggtgctgg cgagcatatt aaatttgttt cgcgttcctg gaaccggttg aacctctacg
    11341 ttgaaaccaa gatcgctgaa ccagcctgca agcaaagtga ttaaagacgc attactttga
    11401 tccagggatt cttcggttgc gcttatcgac ggtgtggcaa tcagagcgcg gtaaatctcg
    11461 ataaatggcg gtaaaacgtt tttcattgtt gacacacctc aggtcatgat agtatcaata
    11521 ttcatgcatt aattatgaat aaaaatacat taacgttgag cataaaggaa cccgatgttg
    11581 aatacgctga ttgtaggcgc tagcggttat gcgggcgcag agcttgtaag ctacgtaaat
    11641 cgccacccac atatgaccat aaccgctttg accgtctcag cgcaaagcaa tgatgcagga
    11701 aagttaattt ctgatttaca tccgcagtta aaagggattg ttgacctgcc attgcaaccg
    11761 atgtcggatg tacgtgactt tagcgcagat gttgatgtgg tgttcctggc gacagcgcat
    11821 gaagtgagcc acgatctggc gccgcagttt ttacaggccg gatgcgtcgt attcgatctt
    11881 tccggcgcgt ttcgggtaaa cgatcgcgcc ttctatgaaa agtattacgg atttactcat
    11941 cagtatcctg agctgctgga gcaggcggtg tacggtctgg cggagtggaa tgccgataaa
    12001 ctgaacacgg cgaatctgat tgcggttcct ggttgctatc caaccgcagc gcagttgtcg
    12061 ctaaaaccgc tgattgacgg cgggcttctc gatctgacgc agtggccggt aattaatgcc
    12121 accagcgggg tgagcggcgc ggggcgcaag gcggcaatat cgaacagttt ctgtgaagtg
    12181 agtttgcaac cgtatggtgt gtttacgcat cgtcatcagc cggaaatcgc tgcccatctg
    12241 ggcgcggagg tcatcttcac cccgcatctg gggaatttcc cgcgcgggat tctggaaacc
    12301 attacctgcc gcctgaaagc gggagtaacc catgcgcagg tcgccgacgt gttgcaaaaa
    12361 gcctatggcg acaaaccgct ggtgcgcctg tatgacaaag gcgttccggc gttaaagaac
    12421 gtcgtcgggc tgccgttctg cgatattggt tttgccgtcc agggcgaaca tctgattgtg
    12481 gtggcaaccg aagacaactt gttgaaaggc gcagcggcgc aggcggtgca gtgcgctaat
    12541 attcgttttg gcttcgctga aacgcagtct cttatttaag ggtgaaatga tgaatccatt
    12601 aattatcaag ctgggtggcg tattactgga tagcgaagag gctctggaac gtctttttac
    12661 cgcgctggtc aactatcgtg agtcccatca gcgtccgctg gtgattgttc acggcggcgg
    12721 ttgcgtggtg gatgagctga tgaaagggct taatttgcca gtgaaaaaga aagacggcct
    12781 gcgcgtgacg cctgccgatc agattggcat cattaccggt gcgctggcgg gaaccgctaa
    12841 caaaactctg ctggcttggg cgaagaaaca ccatatcgcc tctgttggtc tgtttctggg
    12901 cgatggcgac agcgtaaacg tgacccaact cgatgaagcg ttaggccacg tcgggctggc
    12961 gcaaccgggg tcgccgaagc tgattaacat gttgctggaa aacggctttc tgccggtggt
    13021 cagctccatt ggcgtaacag acgacggcca actgatgaac gtcaacgccg atcaggcggc
    13081 aaccgcgctg gcggcgacgc tgggggccga tctgatcctg ctttctgacg tgagcggtat
    13141 tctggacggc aaaggccagc gtatcgccga aatgacggcg tccaaagccg aacagcttat
    13201 cgaccagggc attattaccg acgggatgat tgtgaaagtg aatgcggctc tcgatgctgc
    13261 gcgggcgctg ggtcgtccgg tggatattgc ttcctggcgt catgcggaac aattgccggc
    13321 gctgtttaac ggcacgccga ttggcacgcg tattctggct taactatttg ttcgcccgat
    13381 ggcggctgcg ccttatcggg cctacgtgaa cagaaattgt aagccggata agcgtagcgc
    13441 tatccggcag tgaaattcga agaatttaag gaagtctatt atggcacttt ggggtgggcg
    13501 ttttacacag gcggcagacc aacggtttaa acaattcaat gattcgttgc gcttcgatta
    13561 ccgtctggcg gagcaggata ttgtcggttc tgtggcctgg tccaaagcat tggtcacggt
    13621 aggcgtactg actgccgatg agcaacgaca gttggaagaa gcgctgaacg tgctgctgga
    13681 agaggttcgc gcgaatccgc agcaaatcct gcaaagcgat gcggaagata tccatagctg
    13741 ggtggaaggt aagctcatcg acaaagtggg tcagttgggt aaaaagctgc acaccgggcg
    13801 cagccgtaac gatcaggtgg cgacggacct gaaactgtgg tgcaaagaga cggtgatgga
    13861 actgctcacc gctaaccgcc agctacagag cgcgctggtg gaaaccgcgc aggcgaacca
    13921 ggacgcggta atgccgggat atacccatct gcaacgcgcg cagccagtga ctttcgccca
    13981 ctggtgtctc gcgtatgtcg aaatgctggc gcgcgatgaa agccgcctgc aggacacgct
    14041 taaacgtctg gacgtgagtc cgctaggctg cggcgcgttg gcgggaacgg cctatgaaat
    14101 tgaccgtgaa caattggcag gctggctggg cttcacgtct gcgacccgca acagcctgga
    14161 cagcgtgtcc gatcgtgacc acgtactgga actgctttct gatgcggcta tcggcatggt
    14221 gcatctgtca cgtttcgcgg aagatctgat tttctttaat tctggtgaag cgggctttgt
    14281 agagctttct gaccgcgtga cttccggttc atcgttaatg ccgcagaaga aaaacccgga
    14341 cgcgctggag ctgattcgcg gtaagtgcgg tcgcgtacaa ggggcgctaa ccggcatgat
    14401 gatgacttta aaaggtctgc cgctggcgta taacaaagat atgcaggaag acaaagaagg
    14461 gctgttcgat gcgctcgata tctggcttga ctgcctgcat atggcggcgt tggtgctgga
    14521 cggtattcag gtgaaacgcc cacgttgtca ggacgcggcg caacaggggt atgccaacgc
    14581 caccgagctg gcggattacc tggtcgcgaa aggcgtgccg ttccgcgaag cgcaccatat
    14641 tgtcggcgaa gctgtggtag aagctattcg ccagggtaag ccgctggaag cgttgccgct
    14701 ggccgattta cagaaattca gccgcgtgat tggcgacgat gtgtatccga tattgtcttt
    14761 gcagtcgtgt ctggataaac gggcggcaaa aggcggcgtt tctccgcagc aggtggcgca
    14821 ggccatcgac gatgcgaagg tgcgcctcgc gttgtaggcc ttataagcgt agcgccatca
    14881 ggtaatactg cccggccgag catcagcgac gccgggcttt tttacgcaaa aaaaagcgga
    14941 ccagaggtcc gcaaaagttc acgttggctt tagttatttc gggttcgaga gataccctct
    15001 gaacgggcgg tgtcttcaag ggttaaacga gaaaccgctc cgttctgtga tgtattatta
    15061 atcagaaagg ttgataggga taatcgttcg ttgctatgct acctatcgcc atgaactatc
    15121 gtggcgacgg aggatgaata atgaatattc gtgatcttga atatctggtg gcgttagccg
    15181 aacatcgcca tttccggcga gcggcggact cctgtcacgt cagccagcca acccttagtg
    15241 ggcaaatacg taagctggaa gatgagctgg gcgttatgct gctggagcgt acgagccgta
    15301 aggtgctgtt tacccaggcg ggcttactgc tggtggatca ggcgcgtacc gtactgcgtg
    15361 aggtcaaggt gctcaaggag atggcaagcc aacaaggcga gacgatgtcc ggcccgctgc
    15421 atattggttt aatcccaaca attggtccct atttgctgcc gcttatcatt ccaatgttgc
    15481 accagacttt cccgaagctg gaaatgtatc tgcatgaggc gcaaacgcac cagctgttag
    15541 cgcaactcga tagcggcaag cttgactgcg ctattctggc gctggtgaaa gagagcgagg
    15601 cgtttatcga agtgccgctg tttgatgagc ccatgatgct ggctatttat gaagatcatc
    15661 cgtgggcgaa tcgcgatcgc gtgccgatgt ccgatctggc gggcgagaaa ttgctgatgc
    15721 tggaagatgg ccactgtctg cgcgatcagg cgatggggtt ctgttttgaa gcgggagcgg
    15781 atgaagatac ccatttccgg gcgaccagtc tggaaacgct gcgcaacatg gtggcggcgg
    15841 gcagtggtat tacactactc cccgcgctgg ccgtaccgca ggagcgtaag cgcgacggcg
    15901 tggtttatct gccatgcatt aagccggagc cgcgtcgtac cgtggggctg gtttatcgcc
    15961 cgggatcgcc gctgcgtagc cgttatgagc aactggcaga ggccatccgt ggcgcaatgg
    16021 atggacattt cgacaaggcg ttaaaacagg cggtttaagc cgttcaacgc cgcaacccga
    16081 taagcttccg ccatggttgg gtagttaaag gtggtgttaa cgaagtattc gatggtgtta
    16141 ccgccacctt tctgctccat gatcgcctgg ccgatatgaa taatttcggc ggcgcgttcg
    16201 ccaaagcagt gaatccccag aatttctttg gtttcgcggt gaaagagaat ttttagcgtg
    16261 ccgacgttca tgccgacgat ttgcgctcgc gccagatgct taaactgcgc gcggcccact
    16321 tcgtaaggca ctttcattgc cgttaactgc tgctcggttt tgccgacaga actgatttcc
    16381 ggaatggtat aaatcccggt ggggatatct tcgataagat gcgcggtcgc ttcgcctttc
    16441 accagcgcct gcgctgcaat acgcccctga tcgtaggcgg cggaggccag actgggatag
    16501 ccaatcacgt cgcccaccgc atagacgtgc ggcagggcgg tctggtacat actgttgact
    16561 ttgagctgtc cacggctgtc tgtttccaga ccaatattct ccagcgccag cgaatcggtg
    16621 ttaccggtac ggccattagc atagagcagg cagtcagcct tcagtttttt gccggatttc
    16681 aggtgcatga tgacgccatc atcgcagcct tcgattttct catactcttc attgtggcga
    16741 ataaccacgc cgctattcca gaaatggtaa gagagagagt cggacatctc ctgatcgaga
    16801 aaggccagca ggcgatcgcg ggtgttgatc agatccactt tcacatccat accgcggaat
    16861 atggacgcat attcgcagcc gataacgcct gcgccgtaaa taataacgtg gcgcggttca
    16921 tggtggagac tcaggattga gtcgctgtca taaatgcgcg gatgcgagaa atccacatca
    16981 ttgggatggt aaggacgcga accacaggca ataacaaatt tttctgccgt cagggtttca
    17041 accgtgccgt catggcattc cagcgccagg gtatgttcgt caataaaatg ggcgttgccc
    17101 tgcaagattt cacagtggtt acgctcataa aacccctgac gcatacgcgt ttgttgatta
    17161 atcacgttat cggcatgatt aaggatatcg gcgaaagaag aacgaaggag acgggagtgg
    17221 tcgctataga gcgggttttg attaaattca ataatgcggc tgacggcgtg gcgaagggct
    17281 ttggatggaa tggtgcccca gtgggtacat ccgccgccaa cgttatgata acgctcaatc
    17341 accgcgacgc gtgctccttg cttaaccaga cccattgcag cgccttcacc gccggggcct
    17401 gaccctatga cgactgcatc ataatcccag gaatgtggca tggtattact cacctgtttt
    17461 tatacataaa ataaacacga tgataacatt tgcccagctt taacccaatt atcgttgtgc
    17521 ttttttgcga agccggagca caaactgtct gtaaacaatc attcacaatc cagtgtgaac
    17581 ccgttacttt tattctctgg tatagtgccg aataaggcat atggaaggat tcagacattg
    17641 tgatgggtgt tagagcgcaa caaaaagaaa aaacccggcg ttcgctggtg gaagccgcat
    17701 tcagccaact gagcgctgag cgaagtttcg ccagcctgag tttgcgtgag gtggcgcgtg
    17761 aagcgggcat tgcgccaacg tcgttttacc gtcattttcg cgatgtcgat gaactcggtc
    17821 taacgatggt ggatgaaagc ggtctgatgc tgcgtcagtt gatgcgtcag gcgcgacagc
    17881 gtatcgcgaa aggcggcagc gtcattcgca cgtcggtctc tacatttatg gagtttatcg
    17941 gcaacaatcc caacgccttc cgtctgttgt tgcgcgagcg ttccggcact tccgcggcgt
    18001 ttcgtgccgc cgtcgcgcgg gagattcagc attttattgc ggaacttgcc gactatctgg
    18061 aactcgaaaa ccatatgccg cgcgcgttta ctgaagccca ggccgaagcg atggtgacta
    18121 ttgtctttag cgcgggcgca gaggcgttgg acatcggcgc tgaacagcgt cggcaattag
    18181 aagagcggct ggtattgcaa ctgcgcatga ttgcgaaagg ggcgtattac tggtatcgcc
    18241 gtgagcaaga gaaaatagca catcattccg aataacgtga aggacgagta atgaaacagt
    18301 caggtcaaga taaaggtacg ctgttgctgg cgctcatcgc tggcttatcg attaacggca
    18361 cattcgcggc gctgtttagc gctattgtgc cgttctccgt attcccggtt atctcgctgg
    18421 tactgacggt atattgcctg catcagcgct accaaaatcg tactatgccg gtaggtttgc
    18481 cggggttggc cgccgcttgt ttcattcttg gcgttttact gtatagcact gtcgtgcgtg
    18541 cagaatatcc ggatatcggc tctaatttct tcccggcggt gctgtcggtg attctggtat
    18601 tctggattgg ctttaagctg cgtaaccgca agcaggacac cgcggagtag tgtgcgaatg
    18661 ccggatggcg gtataaccgg ccatccgacg tacattttac cttgcggtga gtaatacccc
    18721 gcattccata tgatgcgtat acgggaactg atcgaatagc gccaggcgag acaccgtgtg
    18781 cgtctggctt aacgtttcca ggtttttgca caacgtttcc ggattgcagg aaatgtacag
    18841 aatacgtgga taagcctgca ccattttttc tgtttcgctg tccagaccgc tgcgcggcgg
    18901 atcgacaaaa atggtttcgc actgatagcg cttcaggtcg atcccctgca ggcggttaaa
    18961 ctcacgaacg ccgttcatcg cctgggtaaa ctcttccgcc gccatgcgaa taatttgcac
    19021 attatcaata tgattagcgg caatattgta ctgtgcggca gcgacggacg gtttggcgat
    19081 ttcggttgcc agcacgcggt taaaattgcg cgccagcgct aaagaaaaat tgccgttgcc
    19141 gcaatacaac tcaagcagat cgccttttga gtctttcgtc acctccagcg cccactctaa
    19201 catctgaata ttcatggcgg cgtttggctg cgtaaagctg ttttcgacct ggcggtagat
    19261 gatctcttta cctgccacag gcagacgctc atcaatataa tcctgatcca attcgatctt
    19321 ggttttagta gcccggccaa tcaggtgtac gttcagacct tgcgcgcgta aagcatcgcg
    19381 taacgcagtg gcggcttcac gccactcttc gtccagcttc ttatggtaca gcaacgacac
    19441 taccgcctgg ttgctcaagg tcgtgagata atcgatctgg aacagcttat gccgcagtgc
    19501 atgattatcg cgcacgccgg caatcatcgc cttcattaag gtattaatca gttggctggc
    19561 cgccgggaag gtgtcaacgc gaatccggct tttggtctgc tgatcaaaca taatgtggta
    19621 caggttatcg ccgtcatgcc acaggcgaaa ttccgcacgc atacgatagt gactgaccgg
    19681 cgagcgaaat acttccggaa ccaggccaga aaacggcgcc atcatactct gcaagcgcgc
    19741 cactttttcg gccagctgcg cctcatactg ttctgtcgga agatgttcgg gggtcatatc
    19801 gcatcctgaa taataaaagt acgcggggat tgtagggatt gctcagtgga tgtccagcta
    19861 ttgatgattt ctgatttgtg atgcgcggtc tggacagggt gttgtgacag acggtagcat
    19921 ccgtgggccg gtcctgtgag ttaataggga atccagtgaa aatctggagc tgacgcgcag
    19981 cggtaaggaa aggtgagatg agagcgtaag cagacactgc ctccggcggg aagtcatcat
    20041 ttctgctatc cagtcaacgg ataaccctcc aagcccgaag acctgccggc taacgtcgca
    20101 tctggttttt catcatcgcg tactatcgat gaagcctgcg gcatccttct tatattgtgg
    20161 atgctttaca atgattaaaa aagctacgct gctgacggcg ttctccgtca cggccttttc
    20221 agcttgggcg caggacacta gcccggatac actggttgtc accgccaacc gttttcagca
    20281 gccgcgcagc gcggttctgg cgcccgttac catcgtgacg cgtcaggata ttgaacgctg
    20341 gcaatcgacc tccgtaaatg atgttctacg ccgtttgcct ggcgtcgata ttgcgcagag
    20401 cggcggcacc ggacaaaact cctccatttt cattcgcggc accaactcca gccatgtact
    20461 ggtattgatt gacggcgtgc gtctgaattt agcaggcgtg agcgggtccg ccgatctcag
    20521 ccagttcccg gtgtcgctgg tacagcgcat tgaatatatt cgcggtccgc gttccgctat
    20581 ttatggttcc gatgctatcg gcggcgtagt gaatatcatt acgacgcgcg ataacccagg
    20641 cacagaatta accgctggat ggggaagcaa tagctaccag aattacgacc tctcgacgca
    20701 acagcaactt ggcgaaaaca cgcgggcgac gttgatcggc gattacgaat acaccaaagg
    20761 gtttgacgtg gtagcgaaag gcggtaccgg gatgcaggcg cagcctgacc gggacggctt
    20821 tttgagtaaa acgctttatg gcgcgttaga gcataccttt tctgatcgct ggagcggatt
    20881 cgtgcgtggt tatggctacg ataaccgtac cgattacgac gcctattact cgccgggctc
    20941 gccgctgatt gatacacgca aactttatag ccaaagctgg gacgccgggc tgcgctttaa
    21001 tggcgaacgt attcagtctc agctagtttc aagctatagc cacagtaaag attacaacta
    21061 tgatccgcac tatggtcggt atgatacctc cgccacgctg gatgagatga aacagtacaa
    21121 tgttcaatgg accaacagtg tggttgtggg gcacggtaat gttggggcgg gcgtagactg
    21181 gcagaaacag actaccacgc caggtaccgg ctatgtgccc gagggatatg accagcgtaa
    21241 taccggggtt tacctgacag gattacaaca gttgggtgac ttcaccctgg aagcggcggc
    21301 gcgcagtgat gacaactccc agtttggtcg tcacggtaca tggcaaacca gcgcgggatg
    21361 ggagtttata gaaggttatc gctttattgc ctcctacgga acctcctaca aagcgcctaa
    21421 tttgggccag ctgtatgggt attacggtaa tccgaacctg aatcctgaaa agagtaaaca
    21481 gtgggaaggc gcatttgaag ggctcaccgc tggcgtcagc tggcgtattt caggttatcg
    21541 taacgatatt aatgacatga tcgattatga cgatcatctg caaaaatatt acaacgaagg
    21601 taaggcgcgt attaaaggta ttgaggcgac ggcgaatttc gataccggac cgttaacgca
    21661 tacggtcagt tatgattacg ttgatgcgcg taatgcgatt accgatacgc cattaccccg
    21721 gcgttccaaa cagatggcaa aatatcaact tgactgggac gtttacgatt ttgactgggg
    21781 ggtgacatat caataccttg gttcccgcta tgattcggat tactccgctt acccataccg
    21841 gacagtaaaa atgggcggcg tcagtttatg ggatcttacg gttgcatatc cggtcacctc
    21901 acatctgaca gttcgtggta aaatagccaa cctgttcgac aaagattacg agacagttta
    21961 tggctaccaa actgcaggac gagaatacac cttgtctggc agctacacct tctgaaccac
    22021 gtcccaccgt gctggtattt gattccggcg tcggtggatt gtcggtctat gatgagattc
    22081 ggcggctcct gccggatctc cactatatat atgctttcga taacgtggct ttcccctacg
    22141 gggaaaagag cgaaacgttt atcgttgagc gcgttgtcga gattgtgact gcggtacagc
    22201 agcgctatcc cctttcactg gcggtgattg cctgtaatac cgccagtacg gtctcacttc
    22261 ccgcattacg tgaaaagttt gccttcccgg tggtgggcgt tgtgcctgcg attaaaccag
    22321 cggcgcggct taccgccaat ggcgtcgtcg ggctactggc gacgagagcc acggtcaaac
    22381 gtccttatac tcacgagctg attgcgcgct tcgccaatga atgtcagata gcgatgttgg
    22441 ggtcggcaga actggtggaa ctggcggaag ctaaattaca tggcgattcg gtatcgctgg
    22501 aagaactgcg ccgtatatta cgcccatggc tacgaatgcc ggagccgcct gacacggtcg
    22561 ttctggggtg tacgcatttc cctctattac gggacgagct tttgcaagtc ctgcccgaag
    22621 ggacgcggtt agtggattcc ggcgcggcga tagcgcgtcg tacagcctgg ctgttggaac
    22681 atgaagcgcc ggatgcgaaa tcaaccgatg ccaatattgc ttattgcatg gcaatgacgc
    22741 caggagctga acaattatta cccgttttac agcgttatgg ctttgaaacg ctcgaaaaac
    22801 tggcggttta atggcgtttt gggtaaatac caggcacttg agaaattatt ttaaatttcc
    22861 tcttgtcagg cagaaataac tccctataat gcgccaccac tgacacggaa caacggcaca
    22921 caggccgccg ggtcagcggg gttcagacca gaatcccacg gagaaaagcg aaaataaacg
    22981 cttgactctg aagcgggaaa gcgtaatatg cacaccccgc gctgctgaga aaaagcgaag
    23041 cggc
//
LOCUS       DAJVKX010000066        23040 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000066 DAJVKX010000000
VERSION     DAJVKX010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23040
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.066"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            243..956
                     /gene="ydiV"
                     /locus_tag="OPY25_002630"
     CDS             243..956
                     /gene="ydiV"
                     /locus_tag="OPY25_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor YdiV"
                     /protein_id="HCS0928218.1"
                     /translation="MIASLDELYHSELFFLPVMDENARLVGLEIIATFAAEDGAVRMP
                     TELVAPRLSVEEQYCLFVEKLALLETCQHFFIQHKLIAWLNLPPAISDLLLLDSELFS
                     RAARFPFFEVAINENYPGLNQGKNNETLANLAMHFPLILANFGAGEASTKAIFDGLFK
                     RVMLDKNFIQQRAEMISFEPFMHAIVAQISSSCESLMIAGIDTEAMFARAAPLGFSAF
                     QGGLWPPVPVSQLIKLVQR"
     gene            1018..2460
                     /locus_tag="OPY25_002631"
     CDS             1018..2460
                     /locus_tag="OPY25_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HCS0928219.1"
                     /translation="MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDELAQQLAIP
                     ASLFDATNGAGVWGGETLLPGMSPVAQVYSGHQFGIWAGQLGDGRGILLGEQLLADGS
                     TLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVASDTPVQ
                     RETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVAEKYA
                     LWFEEVAARTGRLIAEWQTVGFSHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNH
                     SDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQK
                     LGFFTEQKDDNALLNELFSLMAREGSDYTRTFRMLSHTEQQSASSPLRDTFIDRAAFD
                     AWFDRYRARLRTEAVDDALRQQQMQRVNPAIVLRNWLAQRAIDAAEQGDMAELHRLHE
                     VLRQPFTDRDDDYASRPPEWGKRLEVSCSS"
     gene            complement(2496..2687)
                     /gene="hemP"
                     /locus_tag="OPY25_002632"
     CDS             complement(2496..2687)
                     /gene="hemP"
                     /locus_tag="OPY25_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HCS0928220.1"
                     /translation="MSRMDNTELPHPKEIDNETLLPAAERRVNSQALLGPDGKVIIDH
                     NGQEYLLRKTQAGKLLLTK"
     gene            complement(2844..3890)
                     /gene="aroH"
                     /locus_tag="OPY25_002633"
     CDS             complement(2844..3890)
                     /gene="aroH"
                     /locus_tag="OPY25_002633"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HCS0928221.1"
                     /translation="MNRTDELRTARIDSLVTPTELAQRYPVSSSVASHVTDSRRRIEK
                     ILNGEDPRLLVVIGPCSIHDLNAAMEYATQLQAQRQKHQARLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGT
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKDGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHAEDIATACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLDVCDDICQQIRNGSTAIAGIMAESFLREGTQKIISGQPLIYGQSITDPCLNWEDTE
                     VLLEKLAAAVDSRF"
     gene            complement(4046..4879)
                     /gene="ppsR"
                     /locus_tag="OPY25_002634"
     CDS             complement(4046..4879)
                     /gene="ppsR"
                     /locus_tag="OPY25_002634"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HCS0928222.1"
                     /translation="MDNVVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYQQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPGNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLTLPTSLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPCLNSTNYSVEEIATKILDIMGLNRRM
                     Y"
     gene            5216..7594
                     /gene="ppsA"
                     /locus_tag="OPY25_002635"
     CDS             5216..7594
                     /gene="ppsA"
                     /locus_tag="OPY25_002635"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HCS0928223.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVSQLAKAGAQIRQWIIDTPFQP
                     ALENAIRDAYAQLSSDDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAAGRPAIVRRTMGSKKIRMVYAATQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEQHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHAQGKIIAEGRAIGHRIGAGTVKVIHDIGEMNRIEPGDVL
                     VTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGEKV
                     TVSCAEGDTGYVYADMLDFSVKSSSVDTMPELPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQDAALQNDIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRIIVRLSDFKSNEYANLVGGERYEPHEENPMLGFRGAGRYVAESFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVIEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(7694..8452)
                     /gene="aroD"
                     /locus_tag="OPY25_002636"
     CDS             complement(7694..8452)
                     /gene="aroD"
                     /locus_tag="OPY25_002636"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCS0928224.1"
                     /translation="MKTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDI
                     LEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNR
                     AAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRK
                     MQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEV
                     FGSAATFGAVKQASAPGQIAVNDLRSVLMILHNA"
     gene            complement(8515..8622)
                     /gene="rprA"
                     /locus_tag="OPY25_002637"
     ncRNA           complement(8515..8622)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="OPY25_002637"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(8805..9923)
                     /gene="ydiK"
                     /locus_tag="OPY25_002638"
     CDS             complement(8805..9923)
                     /gene="ydiK"
                     /locus_tag="OPY25_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HCS0928225.1"
                     /translation="MVNVRQPRDIAQVLLSVLFLAIMIVACLWIVQPFILGFAWAGTI
                     VIATWPVLLKLQKILWGRRSLAVLVMTLLLVLLFVIPVALLVNSIVDGSGPLIHAVTG
                     GDMTLPDLAWLNNIPLVGAKLYAGWHSLLDMGGSAIMAKVRPYIGTTTIWFVGQAAHI
                     GRFMMHCALMLLFSALLYWRGEQVAMGIRHFACRLAAKRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGVGLAISGVPYATLLTVVMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSAVVGTLDNVIRPVLIRMGADLPLLLILSGVIGGLIAFGMIGLFIGPVLL
                     AVTWRLFSAWVHEVPAPTNEPEEILEELDDIEEANKQS"
     gene            10188..13244
                     /locus_tag="OPY25_002639"
     CDS             10188..13244
                     /locus_tag="OPY25_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCS0928226.1"
                     /translation="MIPQISQAPGVVQLVLNFLQALEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALLARLAAEPRFTSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRYMNRIIEINPEEGCVRVEAGVIKDQLNQALKPYGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGIRAVLLGGDILDTQSMPVDLARTLGENTTTPGRIYQTVY
                     QSCLENRQLILDSFPKLNRFLTGYDLRHVFNDDMTRFDLTRILTGSEGTLAFITEARL
                     DITPIPKVRRLVNVKYDSFDSALRNAPFMVDARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDKEMLGLNIVEFAGDDEALIDGQVEALCHRLDGLMARAEAGVIGWQLCTDL
                     TGIERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDGHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQELLMKQISDEVVALTARYGGLLWGEHGKGFRAEY
                     SPAFFGEVLYGELRKIKAAFDPHNRLNPGKICPPQGIEAPMMKVDAVKRGTWDRQIPL
                     AVRQTWRGAMECNGNGLCFNFDAKSPMCPSMKISLNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEKELPEKRASLRTLIARTRNSWHKRKGEYDFSHEVKEAMSGCLACKACTTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPVRDHLVATVETYAPLMARAPKTFNFFINQPVVR
                     NLAKKHIGMVDLPLLSAPSLQQQLVGHPSANMTLEQLERMSAEQKAKTVLVVQDPFTS
                     YYDARVVADFIRLAEKLGRRPVLLPFSPNGKAQHIKGFLNRFAKTAKKTSEFLNRIAA
                     LGMPIVGVDPALVLCYRDEYKLALGEQRGDFHVLLVNEWLAQEINARLSVEVSGEPWY
                     FFGHCTEVTALPGAPAQWAAIFAHFGAKLENVSVGCCGMAGTYGHELTNHKNSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRIEGTGVRHPLQALLEIIG"
     gene            13241..13651
                     /gene="menI"
                     /locus_tag="OPY25_002640"
     CDS             13241..13651
                     /gene="menI"
                     /locus_tag="OPY25_002640"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HCS0928227.1"
                     /translation="MIWKREVTLDALNAMGEGNMVGLLDIRFERIGDDTLEATMPVDH
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTQGEQKVVGLEVNANHVRSARQGRVRGVC
                     KALHTGARHQVWQIEIFDEQGRLCCSSRLTTAIV"
     gene            13750..13938
                     /locus_tag="OPY25_002641"
     CDS             13750..13938
                     /locus_tag="OPY25_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HCS0928228.1"
                     /translation="MSIDLDPTQLAIEFLRRDKTELSPAQYLKRLKQLELEFADLLTL
                     SATELKEEIYFAWRLGVH"
     gene            complement(14226..15572)
                     /locus_tag="OPY25_002642"
     CDS             complement(14226..15572)
                     /locus_tag="OPY25_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCS0928229.1"
                     /translation="MVVTLAYIALFLVFSWAILRINQKSDSLSKSVFIAIFLGAVIGL
                     SLHFISANHTKTIIEWYSIVGNGYVHLLKLVAIPLIFISILSAINKLENSAGIGKMSL
                     TIVGCMLCLVMVAGFIGLLTAHILGLDASAFVHMPSMLTTEEVNKTAAVSIPQLVTSL
                     IPTNIFLDLTGARSVSVIGIVIFTLIAGIALLKVKKEAPEEGQKLSAGINAIQIWVMK
                     MVRIVIALTPYGVMALMTTVFSSYRLEQFASLLGFIGACYIAIFMMFIVHAILLILSG
                     NNPAHYFRMVWPVLTFAFVSRSSAASIPLAISAQEKFGVQSTIANISASFGSSMGQNG
                     CAGIYPAIMVAMIAPTIGIDPLSLHFLAAMLPAIALGSIGVAGVGGGGTFAALIVLST
                     LNFPVALVGIFIAIEPIVDMARTALNVNGSMMSGVLANRILNNNRADDMPAVIDRP"
     gene            15999..16367
                     /gene="sufA"
                     /locus_tag="OPY25_002643"
     CDS             15999..16367
                     /gene="sufA"
                     /locus_tag="OPY25_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HCS0928230.1"
                     /translation="MELHSGTFNPEDFPWQGLTLTPAAAAHIRELAAKQPGMLGVRLS
                     VKQTGCAGFGYVLDTVREPDKDDLVFEAEGAKLFAPLQAMPFIDGTEVDYVQEGLNQL
                     FKFHNPKAQNECGCGESFGV"
     gene            16376..17863
                     /gene="sufB"
                     /locus_tag="OPY25_002644"
     CDS             16376..17863
                     /gene="sufB"
                     /locus_tag="OPY25_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCS0928231.1"
                     /translation="MSRNTEATEEVGIWTGGRLNYKEGFFTQLPTDELAKGISEEVVR
                     AISAKRNEPDWMLEFRLNAYRAWLDMDEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDS
                     CVSQPGAVQQTGANTFLSKEVEDAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPDLVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEGSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKD
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTRSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGADCGAHTFPYVECRNNSAQLELEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            17880..18626
                     /gene="sufC"
                     /locus_tag="OPY25_002645"
     CDS             17880..18626
                     /gene="sufC"
                     /locus_tag="OPY25_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCS0928232.1"
                     /translation="MLSIKDLQVSVEEKAILRGLNLDIRPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGSVTFKGKDLLELSPEERAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRAYRGQASLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKIVAEGVNALRDDKRAFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVRSGDFTLVKQLEEQGYGWLTEQQ"
     gene            18601..19872
                     /gene="sufD"
                     /locus_tag="OPY25_002646"
     CDS             18601..19872
                     /gene="sufD"
                     /locus_tag="OPY25_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCS0928233.1"
                     /translation="MAGLPNSSKALQQWQHLFEEKGEIRTEQARQHFQQMLRLGLPTR
                     KHEDWKYTPLEGLTHSQFIQQCATISAAQRDALALQIDAVRLVFVDGRFMPELSDSTQ
                     NSGFDVSVRDERQTLAAPVHPEVFLHLTESLAQCVTYIQVRRNQRPTRPLLLMHITQG
                     VDSDELNTAHYRHHLTLAEGAEATVIEHYVSLTAAKHFTGARLTMNVADNAQLRHIKL
                     AFENASSYHFAHNDLLLATDASAFSHSFLLGAAVLRHHSSSQLNGENATLRLNSLAMP
                     VKNEVCDTRTWLEHNKGYCNSRQLHKTIVSDKGRAVFNGLINVAQHSIKTDGQMTNNN
                     LLLGKLAEVDTKPQLEIYADDVKCSHGATIGRIDDEQMFYLQSRGIRQQEARHMILYA
                     FAAELTEAIHDSALKQQVLARIGQRLPGGLV"
     gene            19869..21089
                     /gene="sufS"
                     /locus_tag="OPY25_002647"
     CDS             19869..21089
                     /gene="sufS"
                     /locus_tag="OPY25_002647"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HCS0928234.1"
                     /translation="MTFPVEKVRADFPILQREVNGLPLAYLDSAASAQKPNQVIDAES
                     AFYRHGYAAVHRGIHTLSAQATESMENVRKQASRFINARSAEELVFVRGTTEGINLVA
                     NSWGTENIRAGDNIIISEMEHHANIVPWQMLCERKGAELRVIPLHPDGTLRLETLAAL
                     FDDRTRLLAITHVSNVLGTENPLPDMIALARQHGAKVLVDGAQAVMHHAVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMISTVSLTQGTTWAKAPWRFEA
                     GTPNTGGIIGLGAAIDYVTSLGLDKIGDYEQMLMRYALEQLAQVPDITLYGPAQRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAWYGVPAMCRASLAMYNTHEEVD
                     RLVAGLTRIHRLLG"
     gene            21102..21518
                     /gene="sufE"
                     /locus_tag="OPY25_002648"
     CDS             21102..21518
                     /gene="sufE"
                     /locus_tag="OPY25_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HCS0928235.1"
                     /translation="MAALPDKEKLLRNFTRCANWEEKYLYIIELGQRLAELNPQDRNP
                     QNTIHGCQSQVWIVMRRNANGIIELQGDSDAAIVKGLMAVVFILYHQMTAQDIVHFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAATLS"
     gene            21673..22673
                     /locus_tag="OPY25_002649"
                     /pseudo
     CDS             21673..22673
                     /locus_tag="OPY25_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460340.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
     gene            complement(22740..22979)
                     /locus_tag="OPY25_002650"
     CDS             complement(22740..22979)
                     /locus_tag="OPY25_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major outer membrane lipoprotein"
                     /protein_id="HCS0928236.1"
                     /translation="MNRTNKLILGAVVLGSTLLAGCSSNAKIDQLSSDVQTLSAKVDQ
                     LSNDVNAMRSDVQAAKDDAARANQRLDNKVFRICK"
BASE COUNT         5671 a         5681 c         6330 g         5358 t
ORIGIN      
        1 atcatatata atgatataac cgtagcattt acaaacgtac ttttattaaa aacgggcgtg
       61 ctcacgccct gttaaaagta caacattgga tattggttta taatcagagt aagttaaaaa
      121 aaggaaccgg ttcaccggta aacaagaaaa atgatgacgc ttcaattagt atctgaagtt
      181 acgtctgttt ccgtccgtag tgactggatg gtgaatagcg ccctaaccat gggactggcg
      241 taatgattgc ttcacttgat gagctttacc attccgaact ctttttcctt cccgtcatgg
      301 atgaaaacgc tcggcttgtt ggtttagaga ttattgcaac gtttgccgct gaagacggcg
      361 ccgtgcggat gccgactgag ttggtagcgc ctcgcctttc ggtggaggaa caatactgtc
      421 tgtttgttga aaaactggcg ttgttagaaa cctgtcagca cttttttatt cagcataaac
      481 ttattgcatg gcttaattta ccgcctgcaa ttagtgactt attattatta gatagcgaac
      541 ttttttcccg ggcagcgcgc tttccgtttt ttgaagtagc tataaatgag aattatcctg
      601 ggttaaacca gggcaaaaac aatgaaacgt tagctaatct ggcaatgcat ttcccattaa
      661 ttttggcaaa ttttggggca ggcgaggcgt cgactaaagc tattttcgat gggcttttca
      721 aacgagtcat gttggataaa aattttattc agcagcgagc tgaaatgatc tcattcgaac
      781 cattcatgca cgctattgtt gcccagatct cctccagctg cgagtcgctg atgattgccg
      841 gtattgatac tgaggcgatg tttgcgcgcg cagcgccatt ggggtttagc gcattccagg
      901 gcggactatg gcctccggtg ccggtaagcc agctcattaa actcgttcag cgataacctt
      961 tctgtttgcc ggtgtttaac cggtgattaa ccgtctacac tgaagacagg aggccctatg
     1021 accctgtctt ttactgcccg ttggcgcgat gaattgccag caacgtatac cgcgctttta
     1081 cccacaccgt taaaaaatgc gcgactgatt tggtataacg acgaactggc gcagcagtta
     1141 gccattcccg cttcgttatt tgacgctacc aatggcgctg gcgtttgggg cggcgaaacc
     1201 ttattacccg gtatgtcgcc tgtcgcgcag gtatatagcg ggcatcagtt cggcatctgg
     1261 gcgggacaac tcggcgacgg acgcggtatt ttgctgggcg aacagctcct ggcggatggc
     1321 tcgaccctcg actggcatct gaaaggcgcc ggattaacac cctattcgcg aatgggagat
     1381 ggacgcgccg tcctgcgttc aaccatacga gaaagtcttg ccagcgaagc tatgcattat
     1441 ctgggtattc ccactacgcg cgcgttatct atcgtagcca gcgatacgcc ggttcagcga
     1501 gagacgcagg aaacgggcgc gatgttaatg cgtctggcac aaagtcatat gcgttttggt
     1561 catttcgaac atttctatta ccgccgtgag ccggaaaaag ttcagcaact ggctgatttc
     1621 gctattcgtc attactggcc gcaatggcag gatgtagcgg aaaaatatgc tttgtggttt
     1681 gaagaggtgg cggcgcgtac cggaagactc atcgccgagt ggcaaaccgt cggtttttcg
     1741 cacggcgtta tgaatacgga taacatgtcg attctggggc tgaccatcga ctatggcccc
     1801 tttggttttc tcgacgacta cgatcccggc ttcattggta accattccga tcatcaggga
     1861 cgttaccgct tcgataatca accgtcggtg gcgctgtgga atttacaacg tctggcgcag
     1921 acgttaaccc cttttattga gatcgacgcg ttaaacagag cgctggatcg ttaccaggac
     1981 gcgttgttaa cgcactatgg gcagcgaatg cgccagaagc tgggcttctt taccgagcaa
     2041 aaagacgata acgctttact gaatgaattg tttagtctga tggcgcgcga agggagtgat
     2101 tatacccgta catttcggat gttaagccat acggagcaac agagcgcctc ctcgccgttg
     2161 cgggatacgt ttatcgatcg cgcggcgttc gatgcctggt tcgaccgcta ccgggcgcga
     2221 ttgcgcacag aggcggtgga tgacgcgctg cgccaacagc agatgcaacg cgtgaatcct
     2281 gcgattgtgt tgcgcaactg gctggcgcaa cgcgcgatag atgcggctga acaaggagac
     2341 atggcggaac tgcatcggtt gcatgaagtt ttacgtcaac cttttaccga tcgagatgat
     2401 gactatgcca gccgaccgcc ggagtgggga aagcggctgg aggtcagttg ttcaagttag
     2461 ccagatgcca gcagaatcgt ctgctggcgg gagcgctatt tggttaacag tagcttaccg
     2521 gcctgagttt tgcgcaacag atactcctga ccgttgtgat cgataatgac tttgccgtcc
     2581 ggacctaata gcgcctgact gttgacgcgc cgttcagcgg cagggagaag cgtttcattg
     2641 tctatttcct tagggtgagg cagctcggtg ttatccatac gcgacatgtt atttattaat
     2701 aatcaaactc acaatgatta ttattatcaa taattaatgc gataacagca agtgctaatt
     2761 ctgtggagtg atatacgcgc gcgtagagaa aagggtgggt aacgcatcga agaaacgccc
     2821 atcccggcag gatgggcgag ctattaaaag cggctgtcta ccgccgcggc aagtttttcc
     2881 aacagaactt ccgtatcttc ccagttcagg cagggatcgg taatggattg accatagatt
     2941 aacggttgac cgctgataat tttttgcgtg ccttcccgta aaaaactctc tgccataatc
     3001 ccggcaattg ccgtggagcc attacgaatc tgctggcaaa tatcatcaca tacgtccaac
     3061 tggcggcgat gctgtttttg acagttgccg tggctgaagt cgacgaccag atgttccggc
     3121 agatcaaatt catgcaacgt gtcgcaggcg gtggcaatat cttcagcgtg gtagttcggt
     3181 tttttaccgc cgcgcatgat gatgtgccca tacgggttgc cactcgtttg gtagatagtc
     3241 atctgtccgt ctttatccgg cgagagaaac atatgactgg cgcgggaggc gcgaatagca
     3301 tcaacggcaa tgcgggtatt gccatccgta ccatttttaa agccgaccgg gcaagagagc
     3361 gcagaagcca tttcccgatg gatttggctt tcggtggtac gcgcgccaat cgttccccaa
     3421 ctgatcagat cggcaataaa ctggccggtg accatatcaa gaaattctgt ggcggtcggt
     3481 actcccagtt cgttcacctg caatagcaag cgacgcgcca gttcaagccc atgattgacg
     3541 cggtaactgc cattcaagtc gggatcggaa atcaggcctt tccatcccac gacggtgcgc
     3601 ggtttttcaa aataggtgcg catgacgatt tccagacgcg cctgatgctt ttggcgttgt
     3661 gcctggagct gcgtcgcgta ttccatggca gcattcagat cgtgaatcga acaggggcca
     3721 atgacgacca gtagccgtgg atcttcacca tttaaaatct tttctatccg gcgtcgggag
     3781 tcggtaacgt gactggcgac ggaggacgat acaggatacc gctgcgcgag ttcggttggt
     3841 gttaccaggc tgtcgatacg cgcagtacgg agttcgtcgg ttctgttcat tacaagtctc
     3901 agaaatttgt tgtttcaacg gcaggactac cgggaagtga tgggcatcac gataaaccaa
     3961 tccctgctga tttcaagtgc gaggcgtgtc acacctcgca ggcagaacgg catgataaca
     4021 aaaaccaatc cattaaacta gtttactagt acatcctgcg gttaagcccc ataatatcga
     4081 gaatcttggt ggctatctct tcaacggaat aattggtgct gttcaggcag gggatctgat
     4141 tcttacgata cagcgcttcg acctccgcca cttccatgcg gcactgacgc aacgaggcat
     4201 agcgactgtt ttcacggcgt tcttcgcgaa ttgccgccag gcgttcaggg tcaattgtca
     4261 ggccgaacag tttatgttgt agcggtttta acgatgtggg cagcgtcaaa ttatccatat
     4321 catcggcgat gaaagggtag ttagccgcac gaataccgaa ttgcattgcc agatagagac
     4381 tggtgggcgt ttttccacag cgcgaaacgc caagtaaaat gacctgggcc tgatcgaggt
     4441 tgcgcaatga aatgccatca tcatgcgcca gggtataatc gatagcggca atacgggcgt
     4501 catacttgtt caggttaccc ggattaagcc catgagtacg atgagcgatc ggcgtcggat
     4561 ccagtttcat ctcctgctga agcggcgcca ccagcgcctg gacgatatcc tggcagaagc
     4621 cttcgctctg caagatgatg gcgcgaattt caggtaaaac aatcgagtaa aacaccagcg
     4681 ggcgaacgcc ggtttgctga taaatggcgt caatttggtc tttgacggcg cgggcgcgac
     4741 tttcgttttc cacgaatggc agcgtgatgc tgctgatcgt caccggaaac tgcgacataa
     4801 ccgcgtgacc caggacctcg gcggtgatgg cggtaccatc agaaatatag aaaacatggc
     4861 gatcaacaac attatccatt ctgttcatcc tgaagagtaa acataattat ctgaaagcat
     4921 aaattaaaag taacgggaaa cgtataactt gtcgcttatt ttataaaatg acaggcactt
     4981 tttataatta atgaaaagtg tgtttcattt ccttgaaacg cagtttatgc cgggagtgat
     5041 taagggaatg ccgtgctatg cgcgggtttg cgcaactacg taaacaatct gaaaaaatga
     5101 aaaaataaat ttgcttgaac gattcaccgt ttttttcgcg ggtttaagta tgccaggata
     5161 aatacgcaac tatgtgtttc ttaaactcgt tcatttatca caaaaggatt gttcgatgtc
     5221 caacaatggc tcgtcaccgc tggtgctttg gtataaccaa ctcggcatga atgatgtaga
     5281 cagagttggg ggcaaaaatg cctccctggg tgaaatgatt actaaccttt ccggcatggg
     5341 cgtatccgtt ccgaatggtt ttgcaaccac tgccgatgcg tttaaccagt ttttggatca
     5401 aagcggcgta aaccagcgca tttatgagct gctggataag acagatattg atgatgtctc
     5461 ccagctggcg aaagcgggcg cgcagatccg ccagtggatt atcgacactc ctttccagcc
     5521 ggcgctggaa aacgccatcc gcgatgccta tgcgcagctt tcgtcggatg atgaaaatgc
     5581 ctcttttgcc gtgcgttcct ccgccacggc ggaagacatg ccagatgctt cgtttgcggg
     5641 tcaacaggaa acgtttctta acgttcaggg cttcgatgcg gtactggtgg cagtgaaaca
     5701 cgtatttgct tctctgttta acgatcgcgc catctcttat cgcgttcacc agggatatga
     5761 tcatcgcggc gtagcgcttt ccgctggcgt gcagcggatg gttcgctccg atctcgcctc
     5821 gtcaggggtg atgttctcta tcgataccga atccggcttt gaccaggtgg tctttatcac
     5881 ctcggcatgg ggactgggtg aaatggtggt gcagggcgcg gttaacccgg atgaatttta
     5941 tgtccataag ccaaccctgg cggcaggccg tccggccatc gtacgccgca ccatggggtc
     6001 gaaaaaaatc cgcatggttt acgccgccac ccaggagcac ggtaagcaag tgaagattga
     6061 ggatgtgccg caggaacagc gcgacatttt ctcgctcacc aacgaagaag tgcaggaact
     6121 ggcgaaacaa gcggtgcaga ttgagcagca ctatggtcgt ccgatggata tcgaatgggc
     6181 gaaagacggt cataccggta agctctttat tgtgcaggca cgtccggaaa ccgtgcgctc
     6241 tcgtggccag gtgatggagc gttatacgtt acatgcgcag gggaaaatca ttgccgaagg
     6301 tcgtgccatt gggcatcgta tcggcgcagg tacggtaaaa gttattcacg atatcggcga
     6361 aatgaaccgt attgagcctg gcgatgtgct tgtcaccgat atgaccgacc cggactggga
     6421 accgatcatg aaaaaagcgg cggcgattgt cactaaccgt ggcgggcgca cctgtcacgc
     6481 ggcgattatc gcccgcgaat tgggcattcc ggcggtagtc ggctgcggcg acgccaccga
     6541 acgcatgaaa gatggcgaaa aagtaaccgt ctcctgtgcg gaaggtgata ccggttatgt
     6601 gtatgccgac atgctggatt tcagcgtaaa aagctccagc gtagatacca tgccagagct
     6661 accgctgaag gtcatgatga acgtcggcaa cccggacagg gcatttgact ttgcctgcct
     6721 gccgaatgaa ggcgtaggtc tggcgcgact ggaattcatc attaaccgta tgattggcgt
     6781 tcacccgcgc gcgttgctgg agtttgacga ccaggatgcc gcgctgcaaa acgacattcg
     6841 tgagatgatg aaagggtttg actcgccgcg tgaattttac gttggtcgac tgacggaagg
     6901 gatcgcgacg ttaggcgccg ccttctaccc gaaacgcatt atcgttcgcc tgtctgactt
     6961 taagtccaac gaatacgcca acctggtcgg cggcgaacgt tatgagccgc atgaagaaaa
     7021 cccgatgctg ggcttccgcg gcgcgggtcg ttacgtcgca gaaagtttcc gcgattgttt
     7081 tgcgctggaa tgcgaagcgg tgaaacgcgt gcgcaacgat atgggcctta ccaacgtcga
     7141 aatcatgatc ccgttcgtgc ggacggtcga ccaggcgaaa gcggtcatcg aagagctggc
     7201 gcgccaggga cttaaacgcg gcgagaacgg gctgaagatc atcatgatgt gcgagattcc
     7261 gtccaatgcc ttgctggctg aacagttcct cgagtatttt gatggcttct cgattggttc
     7321 taacgacatg acgcagctgg cgctggggct ggatcgcgat tccggcgtgg tgtctgaact
     7381 gtttgacgag cgtaacgacg cggtgaaagc gctgctatcg atggcgatcc gcgcggcgaa
     7441 aaaacagggc aaatatgttg gaatttgcgg ccagggcccg tccgaccatg aagactttgc
     7501 cgcctggctg atggaagagg ggatcgacag cctgtcgctg aacccggaca ccgtggtgca
     7561 gacctggctg agtctggcgg aactgaagaa gtaaaccgcg accagataac gctatgctta
     7621 tccggcctgc acaagaaaca tgttgtgtcg gccggatagg gcgtaagttg cccgacgcct
     7681 gcataatgcc ggatcaggcg ttgtgcagaa tcattaatac actgcgtaga tcatttacgg
     7741 cgatttgccc cggcgctgaa gcctgcttca ccgcgccaaa cgtggcggca gagccaaaca
     7801 cttcccctgc cagacgtgaa atgacaccct ctttcgccat tgacatagta attaccggac
     7861 ggtcggcgta atgttgctgc atctccagcg tggcagtgag taacgttaat acatcatgct
     7921 tgctttgcgg cataacggca atcttgggaa tatccgcgcc gagtgcttgc attttacgta
     7981 gccgcagaac catttcctct gcggacggcg tctggtgaaa atcgtggtta gacatcacga
     8041 cataaacatt atgcgcatgg gcataatcga cagtggcttt aacgtcagca tcaccggtaa
     8101 atagctcaag atcgatcata tcgaccaggc cgctgtcgat tgcggcacga ttaagcgtga
     8161 gataatgctg agtggttatt gtctgctcgc cgccttcttt ggcgctgcgg aaagtaaaca
     8221 gtaacggaat gtcaggcatc gcatcgcgga taacacgcgc agcggtaaga acggattgag
     8281 tcgatgcgat atccataaag tgatccacgc gccactccag aatatcgaat gtagcttcgc
     8341 ggtaggccag cgcctccgct ttcacgctat tgatgtctct tcccatcaac gacacgataa
     8401 ttttgggcat cccttcgcca atgataagat tttttacggt gacggttttc atgcgtgtcc
     8461 tgtcagtttt ttttcttctc gccattatga acggtgaggc tggccgcttg aagtaaaaaa
     8521 aaaagcccat cgtaggagac gggcaaagac tacacacagc aattcgttgt ttcactcagg
     8581 ggatttccat gcttataaat caatgtgttg atttataacc gtgtgctaat agtaggcatg
     8641 agcacttttt gcgtcgatca gattcgtctc aatagtttaa aaactgtaac ggatttgcga
     8701 cagaaatgag atgcggcggg gaacagacgg gcgaatcaaa atggggtgtg cgttgaattg
     8761 ataaacgtcg ctaaagcatc gggcggcaat gccgcccgac gggattatga ctgcttgttg
     8821 gcttcctcga tgtcatccag ctcttcaagg atctcctctg gttcattcgt cggcgccgga
     8881 acttcatgta cccatgcgga gaacaaacgc caggtcacgg ccagaagcac cggtccaata
     8941 aacagaccaa tcataccgaa tgcaatcagg ccgccgatta ccccggaaag gatcagaagc
     9001 agcggtaaat cggcgcccat gcggatgagt accgggcgaa tcacgttatc cagagtgccg
     9061 acgacggcgc tccaaaccag cagcacggtg ccccaggtgg tgtcgcctgt ccagtaaagc
     9121 cagataatgg ctggaatcaa taccggcaac ggccccaact gaaccaggca cgaaaggatc
     9181 atcactaccg tcaacagggt agcgtaaggc acgccggaaa tcgccagccc gacgccgcca
     9241 agtaccgcct gtaccagcgc ggtgaccacc acgccaagcg ccacggcgcg gatcgcctgg
     9301 gcagccagca gaaccgccgc atcgccgcgt ttagccgcga gacgacaggc aaaatggcgt
     9361 atacccatcg ccacttgttc gccgcgccag taaagcaggg cgctaaacaa cagcatcagg
     9421 gcgcagtgca tcataaagcg tccgatatgc gccgcctgac cgacaaacca gatcgtggtt
     9481 gtgccgatat aaggccgcac tttcgccata atagcgctac cgcccatatc cagcaggcta
     9541 tgccatccgg catacagttt ggcgccaact aacggaatat tatttaacca tgccagatcg
     9601 ggtagcgtca tatcgccgcc ggtcactgca tggatgagcg ggccgctacc atcgacaatg
     9661 ctgttcacca gcaaggcgac gggaataacg aagagcagca ctaacagcag cgtcatgacc
     9721 agtacggcaa gcgagcggcg gccccacaat attttttgta atttcagcaa aacgggccag
     9781 gtcgcgataa caatcgtacc tgcccatgca aaccccaaaa taaaaggctg tactatccac
     9841 aaacaggcca caatcatgat ggctaaaaac agcaccgata gcagcacttg cgcaatatcc
     9901 ctgggctgac gaacatttac cataaatact tttcaccttt gtctttgcgc cagaacgttg
     9961 gcgcgacgtg aacatgcaaa ccacacccta taatgatgag caatttcagc ggtttttaac
    10021 aggccgattc tgcatgtaat tctgttgggc gcacaggaaa aaaatgtgat acaacaaata
    10081 acgcaacacg caaacgatta agcatccctt cctgtgcgta gaccgctcgc gctcgccggg
    10141 ttgggcgcca ccgttcacaa catagaccgc aggaaaaggt caatataatg attccacaaa
    10201 tttctcaggc acccggcgtc gttcagctgg tgctcaattt tttgcaggcg ctggagcagc
    10261 aagggtttac gggcgatacg gcaaccagct atgccgaccg tctgacaatg tcgaccgata
    10321 acagtatcta ccagcttctt cccgatgctg ttgtgtttcc ccgttctacg gcggatgtcg
    10381 cgcttcttgc ccgtctggcg gcggagccgc gctttacgtc gctgatattt accccgcgag
    10441 gcggcggtac tggcacgaat ggccaggcgc taaaccaggg cattattgtt gatatgtccc
    10501 gctatatgaa ccgcattatt gaaattaatc ctgaagaggg atgtgtgcgg gtagaggcgg
    10561 gagtgataaa agatcagctt aatcaagcgt taaagccgta tggctatttt tttgcgccgg
    10621 aactttccac cagtaatcgc gccacgcttg gcggtatgat taataccgat gcctctggtc
    10681 agggttcgct ggtctatgga aaaacgtcag atcacgtctt aggcatacgg gccgtattgt
    10741 tggggggcga tatccttgac acgcaatcga tgcccgtaga tcttgcccgg acgctgggtg
    10801 aaaacacgac gacgccaggc cgcatctatc agaccgtcta tcagtcctgc ctggaaaacc
    10861 gtcaacttat cctcgatagc tttccaaagc tcaatcgctt cctgacaggc tacgatttac
    10921 gccacgtctt taacgatgac atgacccgct tcgatctcac ccgcatctta acggggtcgg
    10981 aagggacgct ggcgtttatt actgaagccc ggctggatat taccccgata cccaaagtcc
    11041 gccgtctggt gaatgtaaaa tacgactcct ttgattccgc gctgcgtaac gcccctttta
    11101 tggttgacgc gcgcgcctta tccgtcgaga cggtcgattc caaagtcctt aaccttgcgc
    11161 gggaagatat tgtctggcac tccgttagcg aattgattac cgatgtgccg gataaagaga
    11221 tgcttggcct gaatatcgtg gaattcgcgg gtgatgatga agcgcttatt gacggacagg
    11281 tcgaggcgct gtgccaccga ctggatggcc tgatggcgcg tgcggaagcg ggcgtgatcg
    11341 gctggcaact ttgtaccgat ttgacgggta ttgagcgtat ttacgcgatg cgtaaaaaag
    11401 cggtagggct gctgggtaat gcgaaaggcg ctgccaaacc gattcctttt gcggaagata
    11461 cctgtgtgcc gcctgaacat ctggccgatt acatcgccga atttcgcgct ctgctggatg
    11521 gtcatggctt aagttacggc atgttcggcc acgtggatgc cggggtgctg catgtgcgcc
    11581 cggcgctgga tatgtgcgat ccgcagcagg aactgttgat gaaacagatc tccgatgagg
    11641 tcgtcgcgct gaccgccaga tacggcgggt tgttgtgggg cgaacatgga aaaggtttcc
    11701 gtgcggaata cagcccggcc tttttcggcg aagtcctgta tggcgagctg cgcaaaataa
    11761 aagcggcttt tgatccgcat aatcgactta acccgggtaa aatctgtccg ccgcagggga
    11821 tagaggcgcc gatgatgaag gtggatgcgg taaaacgcgg cacctgggat cggcaaatcc
    11881 cgctggcggt gcggcagacc tggcgcggcg ctatggagtg taatggtaac ggcctgtgct
    11941 ttaatttcga tgcgaaaagc ccgatgtgcc cgtcgatgaa aattagcctt aaccggatcc
    12001 actcgccgaa agggcgggcg acgctggtgc gggaatggct ccgtctattg gccgatcgcg
    12061 gcgtcgatcc gttgaagctg gaaaaggagc tgccggaaaa acgcgccagc ttgcgcacgc
    12121 tgattgcccg cacccggaat agttggcaca aacgcaaagg cgagtatgac ttttcccatg
    12181 aagttaaaga ggccatgtcc ggctgtctgg catgtaaagc ctgtacgacc cagtgtccga
    12241 ttaaaatcga tgttccggag tttcgttcac gtttcttaca gctttaccat acgcgttatc
    12301 tgcgcccggt acgcgatcat ctggtggcga cggtcgagac ctacgcgccg ctgatggcgc
    12361 gtgcgccaaa gacctttaac ttttttatta accaaccggt ggttcgtaat ctggcgaaaa
    12421 aacatatcgg tatggtggat ttacctctgc tttctgcccc ttcattgcaa cagcaactgg
    12481 tgggccatcc gtctgccaat atgacgcttg agcaactgga gcgcatgagc gccgagcaaa
    12541 aagcgaaaac ggtactggta gttcaggatc cgtttaccag ctactacgac gctcgggtcg
    12601 tagcggactt tatccgcctg gcggaaaaac tgggcaggag gccggtattg ttaccgttct
    12661 cgccgaatgg taaggcgcag catattaaag gttttcttaa tcgctttgcg aaaacggcga
    12721 aaaaaacctc tgagttcctt aatcggatcg ccgcgttggg gatgccaata gtgggcgtcg
    12781 atccggcgct ggtcctgtgt tatcgcgacg aatataaact ggcgctgggc gaacagcgcg
    12841 gcgattttca tgtgttgctg gtgaatgaat ggctggcgca ggaaataaat gcaagactgt
    12901 ccgtcgaggt aagcggtgaa ccgtggtact tttttggtca ttgtacggaa gtcacggctt
    12961 tacccggcgc gcctgcgcag tgggccgcca tctttgccca ttttggcgcg aagctggaaa
    13021 atgtcagcgt aggctgctgc ggtatggcgg gcacttatgg acatgaactc accaatcata
    13081 aaaattcgct gggaatttat gagctatcct ggcatcaggc gatgcaacgt ctaccgcgaa
    13141 accgctgcct ggcaaccggc tattcctgcc gaagccaggt taaacgcatt gaaggtacgg
    13201 gcgtgcgtca cccgttgcag gcattactgg agattatagg ttgatctgga aacgtgaagt
    13261 gaccctcgat gcgcttaatg cgatggggga agggaatatg gttggcctgc ttgatatccg
    13321 ctttgagcgt attggggacg atacgctgga agcgacaatg cccgtcgatc atcgcaccaa
    13381 acagccgttc ggcttgctgc atggcggagc gtctgtggtg ctggcggaaa gtatcggctc
    13441 ggtcgcaggc tatctgtgta cgcaggggga gcaaaaggtg gtggggctgg aggtgaatgc
    13501 caaccatgta cggtcggcgc gtcaggggcg cgtacgaggc gtctgtaaag cgttgcatac
    13561 cggggctcgc catcaggtct ggcagataga gatctttgat gaacagggac gtctgtgctg
    13621 ttcttcgcgc cttactacgg cgattgtgtg acgttgtcac cataaaagtg tgatgcatat
    13681 tgcttttggt caaaatgtgc gcagaaaaag gtgatatact gtgcacgttt acacataagc
    13741 gaggatgata tgtctattga tttagaccca acccaactgg cgattgaatt tttacgccgt
    13801 gataaaaccg aactttctcc cgcgcagtat ttgaagcgtt taaaacagct ggagttagag
    13861 tttgccgatc tcctcaccct ctctgcaacc gaactgaaag aagagatcta tttcgcctgg
    13921 cggttgggcg tgcattaata gagtctgtgt aggccggata aggcgttagc cgccatccgg
    13981 ctatgttacc aggcaatctc accagacact gtcccccggt aatagataac ccccttgatt
    14041 ttgtgtaaaa aaaatacaga tcgccatttg tgctaaaaag gtgcgctctc tttatgagat
    14101 tattcttatg ccccttcaag agctaagcca ttaagagtgc cggagataag cgccggatgg
    14161 ggccggaacc cttaagcctg tattgaacag acttaagggt ttttcttttc cgggcgcgta
    14221 aaaaactaag gtctgtcaat aaccgctggc atgtcgtcag ccctattatt attcaaaata
    14281 cggttagcca gcacacctga catcatcgat ccgttaacgt tcagagccgt gcgggccata
    14341 tcaacgatag gttcgatggc aataaaaata ccgaccagcg caacgggaaa attcaacgtc
    14401 gacaggacaa tcagcgccgc gaacgtacca ccgccgccga cgccggctac gccaatagac
    14461 cctagcgcaa tggcaggcaa catcgcggcc agaaaatgca gcgagagcgg atcgatgccg
    14521 atggtgggcg caatcatcgc taccataata gccggataaa tcccggcgca gccattttgc
    14581 cccatactgg agccaaacga ggcggaaata ttggcaatgg tgctttgtac gccaaatttt
    14641 tcctgggcgg aaatggccag cggaatagag gctgcgctgc tgcgggagac aaacgcaaag
    14701 gttaagacgg gccagaccat tctgaaataa tgcgctggat tattaccgct gaggatcagc
    14761 aagatggcgt gcacgataaa catcatgaaa atcgcgatat aacaggcgcc gataaaacca
    14821 agtaagctgg cgaattgttc aaggcggtat gatgaaaata cggtggtcat taatgccatg
    14881 acgccatagg gcgttaatgc aataacgata cgtaccatct tcatgaccca gatctggata
    14941 gcgttaatgc ctgcgcttaa tttctgacct tcttccggcg cctctttttt gacctttaac
    15001 agggcgatcc ccgctattag cgtgaagata acgatgccga taacggaaac acttctggct
    15061 cccgtaagat caagaaaaat atttgtcggg atcagcgatg tcactaactg gggaatcgac
    15121 accgcggcag tcttattgac ttcttctgta gttaacattg acggcatgtg cacaaaagcg
    15181 ctggcgtcaa gccccagtat atgagcggtc agtaatccga taaaaccggc aaccatcacc
    15241 aggcataaca tgcatccgac gatcgtcagc gacatttttc cgatgccggc gctattttcc
    15301 agtttattga tggcggaaag aatagaaata aaaattagcg gtatagcgac cagttttaac
    15361 agatggacgt agccattgcc gacgatgctg taccattcga taatggtttt agtgtgattt
    15421 gctgaaataa aatgcaggga taaaccaata acagccccta aaaagatagc gataaaaacg
    15481 cttttcgaca gggaatcgct tttttgatta attctcaaga tggcccacga gaaaaccaaa
    15541 aaaagtgcga tatacgcgag cgtaacaacc atattttaag cctcttgcct cattcagcac
    15601 ctgaaatgcc ggaaagagtt tacataaacc tatagctcaa actgagttat agaaccgcag
    15661 cggattataa agagcgcaac gccaggtatc catacaaaaa atggggttct gacctcgccg
    15721 cccggcaatg tcgacagcct attaattaaa tagtcatttt ctatacatct tttcgttttt
    15781 gacctgccag aacggttaat gtcttataaa tcattactta tcaaaaagtt aagtggtttt
    15841 ttgtctgtcg tatgacctgg cggacagggt ctatgcttaa taaaaggcgc tcaatatgac
    15901 catttgttgg aaagcccctg cggttaaggg gttgaagtga taatcattat cactaacatg
    15961 ctgttatatc ctggtgattt agaacgcgag gtaactctat ggaattgcat tcaggcacgt
    16021 ttaacccgga ggacttcccc tggcaagggc tgacgctaac gccagcggcg gcagcgcaca
    16081 tacgtgaact ggcagcaaag cagccgggca tgttgggcgt gcggttaagc gtaaaacaga
    16141 cgggatgtgc cggatttggc tatgttctgg ataccgttcg ggagccggat aaagacgatc
    16201 tggtttttga agccgaaggc gcaaagcttt tcgcaccgtt acaggcgatg ccttttattg
    16261 acggaacaga agtggattac gtacaggaag ggctgaacca gttatttaaa tttcataacc
    16321 ccaaagccca gaatgaatgt ggctgcggcg aaagttttgg ggtataggcg gtactatgtc
    16381 tcgtaatact gaagcaacgg aagaggtcgg catctggaca ggcggacgcc ttaattacaa
    16441 agaaggattt ttcacgcaat tacccactga tgaactggca aaaggcatca gcgaagaggt
    16501 ggtgcgtgcg atttccgcaa agcgtaacga acctgattgg atgctggaat ttcgcctcaa
    16561 tgcctataga gcctggctgg acatggatga accgcactgg ctgaaagcgc attacgataa
    16621 actgaactat caggactaca gctattactc tgcgccatca tgcggaaact gcgacgatag
    16681 ctgcgtttcc cagccgggag ccgtacagca aacgggcgcg aatacctttt tgagtaaaga
    16741 ggttgaagac gctttcgagc aacttggcgt tccggttcgc gaagggaaag aggtcgccgt
    16801 tgatgcgatt tttgactcgg tctccgtagc gaccacatac cgtgaaaaac tggcggaaca
    16861 gggcattatt ttctgttctt ttggcgaagc gatacacgat caccctgacc tggtcaggaa
    16921 atatcttggc accgtcgtgc cggggaacga taactttttt gccgcgctga atgcggcagt
    16981 cgcttccgat gggacattta tctatgttcc caaaggcgtg cgttgcccaa tggagttatc
    17041 cacctatttt cgcattaacg ctgagaaaac cggtcagttt gagcgcacga ttctggtggc
    17101 ggatgaaggc agctatgtga gttatatcga aggctgctcc gcgcccgtac gcgacagtta
    17161 tcagctccac gccgcggtag tggaagtcat catccataaa gatgctgaag taaaatattc
    17221 caccgtacaa aactggttcc cgggcgacaa caacacgggc ggcattctga actttgtgac
    17281 caagcgggcg ttgtgcgaag gggaaaacag caagatgtcg tggacccagt cggaaaccgg
    17341 ttcggcgatt acctggaaat acccgagctg cattctgcgc ggtgataatt ctatcggcga
    17401 gttctattcc gttgcgctga ccagtggaca tcagcaggct gacaccggca ccaaaatgat
    17461 ccatatcggt aaaaacacgc gctcaaccat tatctcaaaa ggcatttccg ccggccacag
    17521 ccagaacagc taccgtgggc tggtaaaaat tatgccgacg gcaaccaacg cccgaaattt
    17581 cacccaatgc gactccatgt tgattggcgc ggactgcggc gcgcatacgt tcccgtatgt
    17641 tgaatgccgc aataacagcg cgcagctgga gctcgaggcg acgacatcac gcatcggtga
    17701 agatcagctt ttctattgtc tgcaacgcgg catcagcgaa gaagacgcta tttcgatgat
    17761 cgtcaacggt ttctgcaaag acgttttctc ggaactgccg ctggagttcg ccgttgaagc
    17821 gcaaaaactg ctggcgatta gccttgagca cagcgtcggt taatgatgaa ggaaaaccca
    17881 tgttaagcat taaagattta caggtcagtg tggaagaaaa ggcgattttg cgtggcctga
    17941 atctggatat tcgccccggc gaagttcacg ccattatggg gccgaacggt tccgggaaaa
    18001 gcacgctctc cgccaccctg gcgggacgtg aagattatga ggtcaccggc ggctcggtta
    18061 cgttcaaagg taaagatctg cttgaactgt cgccggagga acgggcgggc gaagggattt
    18121 ttatggcctt ccagtacccg gtagaaatcc ccggcgtcag taaccagttt ttcctgcaaa
    18181 ccgcgctgaa tgccgtgcgc gcctatcgag ggcaggcgtc gttggatcgc tttgattttc
    18241 aggatctgat ggaagaaaag atcgcattgc tgaaaatgcc ggaagatttg ctgacccgtt
    18301 cggtaaacgt cggtttttcc ggcggggaga aaaagcgcaa tgatattttg caaatggcgg
    18361 tgctggaacc ggaactgtgc attcttgatg agtcggactc cggactggat atcgatgcgt
    18421 tgaaaattgt ggcggaaggc gtcaacgcgt tacgcgacga taaacgcgct tttattatcg
    18481 tgacccacta tcagcgcata ctggactaca tcaagcctga ttacgtccat gtcctctatc
    18541 aggggcgaat tgtccgttcc ggcgatttta ctctggtcaa acaactggag gagcagggtt
    18601 atggctggct taccgaacag cagtaaagcg ctacagcaat ggcagcatct ctttgaagaa
    18661 aaaggagaaa ttcgaactga gcaggcaaga caacatttcc aacagatgtt acgtctggga
    18721 ttgccgacgc gtaaacatga agactggaaa tacacgccgc tggagggctt aacccatagc
    18781 cagtttatcc agcagtgtgc gactatcagc gccgcccagc gtgatgcgct ggcgctgcaa
    18841 atcgatgccg tgcggctggt gtttgtcgac ggacggttta tgccagagct cagtgatagc
    18901 acgcaaaaca gcggatttga cgttagcgtc agagatgagc gccagacgct tgccgcgccg
    18961 gtacatcccg aggtttttct gcatctgacg gaaagcctgg cgcaatgtgt cacgtatata
    19021 caggtacggc gaaatcagcg tccgaccagg ccgctactgt taatgcatat cacgcagggc
    19081 gtggatagcg acgagctgaa taccgcgcat tatcgccacc atctgacgct ggcagaaggc
    19141 gcggaagcga cggttattga gcattatgtc agccttacag cggcaaaaca ttttaccggc
    19201 gcgcgtctga cgatgaacgt tgcagacaat gcgcaactgc gtcatatcaa actggcgttt
    19261 gaaaatgcgt ccagctatca ctttgcgcat aacgatcttc tgctggcgac agacgcctcg
    19321 gcgtttagcc acagttttct gctgggcgcc gcagtactac gtcaccacag cagctcacaa
    19381 ctgaatggcg aaaacgcgac gcttcgactg aatagtctgg cgatgccagt gaaaaatgaa
    19441 gtctgcgata cgcggacatg gctggaacat aacaaaggct actgtaacag ccgccagttg
    19501 cacaagacca tcgtcagcga caaaggacgc gcggtcttta atggcctgat taacgtggcg
    19561 caacactcca ttaaaaccga cggccagatg accaataata acctattgtt ggggaaactg
    19621 gctgaagtcg ataccaaacc gcaattagag atctatgccg atgacgtgaa gtgcagccac
    19681 ggcgcgacga tcgggcgtat tgacgatgag cagatgtttt atctgcaatc acgcggcatc
    19741 aggcagcagg aggcgcggca catgattctt tacgcgtttg ccgcagagtt aacggaagct
    19801 atccatgata gcgcccttaa acagcaggtg ctggcgcgaa tcggccagcg actgcccgga
    19861 ggcctggtat gacatttcct gtagaaaaag tacgggcgga ttttcccata ctgcagcgtg
    19921 aagttaacgg cctgccgctg gcttacctgg acagcgcagc cagcgctcaa aaacctaatc
    19981 aggtgattga tgctgaatct gccttctacc gtcacggcta tgctgcggta catcggggta
    20041 tccatacgtt aagcgcgcag gcgaccgaaa gcatggagaa tgtgcgtaag caggcgtcgc
    20101 ggtttattaa cgcccgctcc gcagaagaac tggtgttcgt gcgcggtacg acggagggca
    20161 ttaaccttgt cgccaacagt tggggaacgg aaaatattcg cgccggggat aacattatca
    20221 tcagcgagat ggagcatcac gccaacatcg ttccctggca gatgctgtgc gagcgcaaag
    20281 gcgctgaact gcgcgtgatc ccattgcatc ctgacggtac gctgcggctg gagaccttag
    20341 ctgcgctgtt cgatgaccgg acccgactgc tggccattac ccatgtatct aatgtgctgg
    20401 ggacggaaaa cccactgccg gacatgattg cgctggcgcg ccagcatggg gcgaaagtgc
    20461 tggtggatgg cgcccaggcc gtgatgcacc atgctgttga cgtccaggcg ctggactgcg
    20521 atttttacgt tttctccggc cataaacttt acgggccgac cggcatcggc attctgtatg
    20581 ttaaagaggc gttgctgcaa gaaatgccgc cgtgggaagg gggcgggtcg atgatctcga
    20641 ccgtcagcct gacgcaggga acgacatggg cgaaagcgcc ctggcgtttt gaggcgggaa
    20701 cgccgaatac tggcggcatc atcggtctcg gcgcggcgat tgattatgtg acgtcgctgg
    20761 gactggataa gattggcgat tatgagcaga tgctgatgcg ctatgcgctg gagcaactgg
    20821 cgcaggtgcc tgatatcacg ctatatggcc cggcgcagcg gttgggcgtc atcgcgttta
    20881 atctgggtaa acaccacgct tacgacgtcg gcagctttct tgataattac ggtatcgcgg
    20941 tacgaacggg gcatcactgc gcaatgccgc tcatggcctg gtatggcgtg ccggcaatgt
    21001 gccgggcttc gctggcgatg tataacaccc atgaagaagt ggaccgactg gtggcaggat
    21061 taacgcgtat ccaccgctta ttgggataac agtgaggttt tatggctgcg ctaccggata
    21121 aagaaaaatt gctgcgtaac tttacgcgtt gcgctaattg ggaagagaaa tatttatata
    21181 ttattgagtt ggggcagcgc ctggcggagt taaatccgca ggatcgcaat ccgcaaaata
    21241 cgattcatgg ctgtcagagc caggtgtgga tcgtgatgcg gcgaaacgcc aatggcatta
    21301 tcgaattgca gggcgacagc gacgcggcga tcgttaaagg ccttatggcg gtggtattta
    21361 ttttgtacca ccagatgacg gcgcaggata ttgtgcattt tgatgtccgg ccatggttcg
    21421 aaaaaatggc gcttacgcaa cacctcacac cttctcgttc tcaggggctg gaagcaatga
    21481 ttcgcgcaat tcgcgctaag gccgccactc ttagctaaac tatacagaca gcgttctacc
    21541 tgatgtcaaa tcctttgtcg gacggcgacg tcgctttatc cagagtggac agagcgtata
    21601 ttttgttgtt ctgataagcg aagcgctacc agccgtcgca gagggcatca ccaggaatac
    21661 aggaggtttg gtatgaaacg tgcgtctttc attacgctaa ctattatcgg cgcgtatagc
    21721 gcgttacagg cagcctgggc ggttgattat ccattaccgc cagaaggcag ccgtcttatt
    21781 ggtcagaatc aaacctatac cgtacaggaa ggtgataaaa acctgcaggc tatcgcccgg
    21841 cgttttgata cggcggcgat gctcatcctt gaagcgaaca atacgattgc gccggtgcct
    21901 aagcccggta cgctaattac cattccctcg cagatgctat tgccggatgc gcccagggaa
    21961 ggcgtcatcg tcaacctcgc ggagctacgg ttgtatttta cccgccggga gaaaaccgcg
    22021 ttcaggtgta tcccatcggc atcggtttgc agggactgga aactcccgtc atggacaccc
    22081 ggatagggca aaagatcccc aacccgacgt ggacgccgac ggcaggcata cgccaacgtt
    22141 cgcttgagcg ggggatcacg ctgccgccgg tgatccctgc cgggccaaat aacccgctgg
    22201 gacgctatgc gctgcgtctg gcgcacggta atggggaata tctcattcat ggcaccagcg
    22261 cgccggatag cgtaggtctg cgcgtgagtt ccggttgcat tcgcatgaac gcgccggaca
    22321 tcaaagcgtt atttgcgcag gtcagaacgg ggacgccggt aaaagtgatt aaccagccgg
    22381 tgaaattctc tgtcgagccg aatggcattc gttatgtaga ggtacacagg ccgctatcgc
    22441 cggaagaaga gcaaaacgtg cagacgatgc cctatgtgtt gcctgcggaa tttaccgcgt
    22501 tcagaaacgc gcaaggggtg gatagtcgcc tggtcgataa ggcgctatac cggcgagccg
    22561 ggtatcctgt cagcgtgagc gccggacaga cgccagcggt aaatacgacc gcagtcgaat
    22621 ccgctcagaa cggttttgtc ggggaagagg ggcaaacgcg cgcgacgcag tagccttcgc
    22681 agtaaatgac ggacaaaaaa atggcgcacg atgtgcgcca ttttatatca tgcgtcaaat
    22741 catttacaga tgcggaatac tttgttgtcc agacgttggt tagcgcgagc tgcgtcgtct
    22801 ttagcagcct gaacgtcgga acgcattgca tttacgtcat tactcagttg atcaacttta
    22861 gcgctcagcg tctgtacatc ggaagacaac tgatcgattt tagcgttgct ggaacaacct
    22921 gccagtaacg tggaacccag aactactgca cctaagatca gtttgttagt gcggttcata
    22981 acaataacct tatattttgt gtggttatat aggtaaaaaa aatggcgcac gatgtgcgcc
//
LOCUS       DAJVKX010000067        22910 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000067 DAJVKX010000000
VERSION     DAJVKX010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22910
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.067"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..761)
                     /gene="fdhD"
                     /locus_tag="OPY25_002651"
     CDS             complement(<1..761)
                     /gene="fdhD"
                     /locus_tag="OPY25_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HCS0928237.1"
                     /translation="MNNILSEEVLNVTDFTTSRQLTLWKREDLQSSQLDDVAEEVPVA
                     LVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSS
                     RRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDF
                     QPTGKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRATEGEEWRQGAALVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVDVAERC"
     gene            956..4006
                     /gene="fdnG"
                     /locus_tag="OPY25_002652"
     CDS             956..4006
                     /gene="fdnG"
                     /locus_tag="OPY25_002652"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1541..1543,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HCS0928238.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPGVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVSRGALCPKGAGLVDFI
                     HSESRLKFPQYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYQAQNAEGVTVNRWLT
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTASVADFYAPIR
                     SGTDIAFLSGVMLYLLTNEKYNREYTEAYTNASLIVREDFGFDDGLFTGYDADKRQYD
                     KTSWHYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKADFLKVCE
                     YIAETSAKDKTASFLYALGWTQHSIGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYLTLPSEKQTDLQTYLAANTPKPLLKDQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKQGKVNGYICQGFNPVASFPNK
                     NKVVASLSKLKYLVTIDPLNTETSTFWQNHGESNDVDPSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIAMTDGEILAGIFLRLRKMYSEQGGANPEQVLNMTWNY
                     TKPYEPASEEVAMESNGKALADLIDPATGAVVVKKGQQLSSFAQLRDDGTTSSGCWIF
                     AGSWTPEGNMMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWEGGKWAGWDIPDYSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDADALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     AQPEQFVEIGEKLANKLGIAHGDTVKVSSNRGYIKAKAVVTKRIRTLKADGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            4019..4921
                     /gene="fdxH"
                     /locus_tag="OPY25_002653"
     CDS             4019..4921
                     /gene="fdxH"
                     /locus_tag="OPY25_002653"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit beta"
                     /protein_id="HCS0928239.1"
                     /translation="MAYQSQDIIRRSATNGFTPAPQARDHQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDEVGNNVGVYDNPADLTAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CADPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFNVPRLNPEDNRVYKC
                     TLCVDCVVVGQEPACVKTCPTGAIHFGSKEDMKTLAGERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGVWKPLAAFGFAATFAASVFHY
                     VGVGPNRAEEEDDNLHEEKDEVRK"
     gene            4918..5553
                     /gene="fdoI"
                     /locus_tag="OPY25_002654"
     CDS             4918..5553
                     /gene="fdoI"
                     /locus_tag="OPY25_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HCS0928240.1"
                     /translation="MKRRDTIVRYTAPERINHWIVAFCFVLAAVSGLGFLFPSFNWLM
                     HILGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTRSWAKKHHPRWYREVRKTTEKETE"
     gene            5550..6479
                     /gene="fdhE"
                     /locus_tag="OPY25_002655"
     CDS             5550..6479
                     /gene="fdhE"
                     /locus_tag="OPY25_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HCS0928241.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKH
                     WQKLLHSLIAELKPEMNGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFI
                     WAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAV
                     ADDLASLVLDARMEQEGFARSSINPFLFPGEGE"
     gene            complement(6517..6891)
                     /locus_tag="OPY25_002656"
     CDS             complement(6517..6891)
                     /locus_tag="OPY25_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HCS0928242.1"
                     /translation="MVKGSALFDTNILIDLFSGRIEAKHALEAYPPQNAISLITWMEV
                     MVGAKKYHQENRTRIALSAFNIIGVTQEIAERSVIVRQEYGMKLPDAIILATAQVHRC
                     ELVTRNTKDFADIPGVITPYHL"
     gene            complement(6891..7133)
                     /locus_tag="OPY25_002657"
     CDS             complement(6891..7133)
                     /locus_tag="OPY25_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HCS0928243.1"
                     /translation="MMAGMDMGRILLDLSDDVIKRLDDLKVQRNLPRAELLREAVEQY
                     LERQDRAETTISKALGLWQGCEEDGVEYQRKLREEW"
     gene            7338..8267
                     /locus_tag="OPY25_002658"
     CDS             7338..8267
                     /locus_tag="OPY25_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCS0928244.1"
                     /translation="MALESGIAQLVEEFIAAGRPSSREQNIDDRRAGYIASTTLAGET
                     ETRVQVEDIELDAMTFRVVSPLNATGKLPCIIYYHGGCFVSGGFATHDNQLRQLAFYS
                     RCRVIAAQYRLAPEHTFPAAHNDAETGANTIWKYAQKLGIDRENITLAGDSAGGHLAL
                     VTALRLKAARQWQPAQLILIYPMLDATARFASYTCNGLDYIITRDTLLSGYEMYMPRT
                     DPLHPEASPLWREDFAGLPSTHIITAEFDPLRDEGEALYQRFQEQGVECTCQRYLGVI
                     HGFFQLGGVSKTARDAIRDVAWRVVSPSTSKMT"
     gene            8353..8664
                     /locus_tag="OPY25_002659"
     CDS             8353..8664
                     /locus_tag="OPY25_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigB family
                     toxin"
                     /protein_id="HCS0928245.1"
                     /translation="MHVISRKLFNEAMLMYPNHELALTELLNVLEKKTFTQPEEMKRY
                     IPSLDNFKYRDKWWVIDVSGNSLRLISYIDFRLHKIFVKHIVSHAEYDKLTAYYRGNE
                     E"
     gene            8661..9107
                     /locus_tag="OPY25_002660"
     CDS             8661..9107
                     /locus_tag="OPY25_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462910.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigA family
                     antitoxin"
                     /protein_id="HCS0928246.1"
                     /translation="MRTHRQMDATSAKKIVDTFSDAVKSVPLMGEDRNDNEYRRALAL
                     VEFLVDHDDLENPLFELLCARISEYEKHAPEFKALNQHLEKTPPGVSVLRTLMDQYGL
                     KAADLANELGSKSNVSNILNGRRALTVNHIKALTQRFKLPADAFIE"
     gene            complement(9122..10063)
                     /gene="fabY"
                     /locus_tag="OPY25_002661"
                     /gene_synonym="yiiD"
     CDS             complement(9122..10063)
                     /gene="fabY"
                     /locus_tag="OPY25_002661"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HCS0928247.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDGWDALAH
                     HQMVVDEEGNLVAVGRLYINADNEASIRFMAVHPSVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVASLDDILHRGDWCGQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTVFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPNAVADLGSLSGDLDRLARGKKARVQL
                     QVELLGGETAGAIFEGIYIVLPAKPFGPYEEGGNEEE"
     gene            complement(10108..10545)
                     /gene="dtd"
                     /locus_tag="OPY25_002662"
     CDS             complement(10108..10545)
                     /gene="dtd"
                     /locus_tag="OPY25_002662"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCS0928248.1"
                     /translation="MIALIQRVTRASVTVEDEVTGKIGPGLLVLLGVEKEDDEQKANR
                     LCERVLGYRIFSDVDGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSGGAAPDRA
                     QALYEYFVERCRQQAINTQTGRFAADMQVELVNDGPVTFWLQV"
     gene            complement(10542..11414)
                     /locus_tag="OPY25_002663"
     CDS             complement(10542..11414)
                     /locus_tag="OPY25_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HCS0928249.1"
                     /translation="MLKTVHQKAGRHTRPVRAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLIAVVFALFAAFPMFSDVSIQLRHFIFANFMPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYAIDSALNTIWRSKRTRPKVYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRILPLLLSWISFWLLYSIVPTTRVPNRDALVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEADQP"
     gene            complement(11408..12007)
                     /gene="yihX"
                     /locus_tag="OPY25_002664"
     CDS             complement(11408..12007)
                     /gene="yihX"
                     /locus_tag="OPY25_002664"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HCS0928250.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGVWSDLSRVPLASLKQKFTMGETF
                     HQHERGEITDEAFAEAFCHEMALSLSYEQFAHGWQAVFVGLRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTHFWPEEYPEVRAAADHIYLSQDLGMRKPEARIYQHVLQKEGFSAAD
                     AVFFDDNADNIEGANQLGITSILVKDKATIPDYFAKLLC"
     gene            complement(12198..13001)
                     /locus_tag="OPY25_002665"
     CDS             complement(12198..13001)
                     /locus_tag="OPY25_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0928251.1"
                     /translation="MSLTELTGNPRHDRLLMLIDERGYMNIDELASLLEVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREISWTQEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEQVARALLNHNHLRIITNSLRVAHILYNNPRFEVMVPGGTLRPHNSGIIGPS
                     AAAFVAGFRADYLVTSVGAIESDGALLEFDVNEASVVKTMMAHSRHILLAADHTKYHA
                     SAAVEIGNVSQITALFTDEYPGPALQNLLQSQQIEVVQVSPSLDDAVSA"
     gene            complement(13035..13931)
                     /locus_tag="OPY25_002666"
     CDS             complement(13035..13931)
                     /locus_tag="OPY25_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462904.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCS0928252.1"
                     /translation="MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATA
                     AVAAAKLGAQVDFIGRVGDDDTGNSLLAELESLGVNTRYTRRYTQAMSSQSAIMVDAK
                     GERIIVNYPSPDLLPDADWLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGC
                     NWLEKAAVRHQPGFTVEVVDTTGAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCT
                     RPGGRAGIPDCEQTRSFLSLFV"
     gene            14096..14993
                     /gene="yihU"
                     /locus_tag="OPY25_002667"
                     /pseudo
     CDS             14096..14993
                     /gene="yihU"
                     /locus_tag="OPY25_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462903.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
     gene            15016..15894
                     /gene="yihT"
                     /locus_tag="OPY25_002668"
     CDS             15016..15894
                     /gene="yihT"
                     /locus_tag="OPY25_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HCS0928253.1"
                     /translation="MNNYTIKDITRASGGFAMLAVDQREAMRLMFAAAGAKTPVADSV
                     LTDFKVNAAKILSPYASAVLLDQQFCYRQAVEQNAVAKSCAMIVAADDFIPGNGIPVD
                     NVVIDKKINAQAVKRDGAKALKLLVLWRSDEDAQQRLDMVKEFNELCHSNGLLSIIEP
                     VVRPPRCGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGARSDLLTASQRLNGHI
                     NMPWVILSSGVDEKLFPRAVRVAMEAGASGFLAGRAVWSSVIGLPDTELMLRDVSAPK
                     LQRLGEIVDEMMAKRR"
     gene            15910..17046
                     /gene="yihS"
                     /locus_tag="OPY25_002669"
     CDS             15910..17046
                     /gene="yihS"
                     /locus_tag="OPY25_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HCS0928254.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFNFGKNAAVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAASMGRPGAYDLVDHGIKALNGALRDKKYGGWYACVNDQG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEVIEKYFWSEEEQMCLESWDE
                     AFSQTEDYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRIASVIIHDVARNNHYRVNE
                     HFDSQWNPIRDYNKDNPAHRFRAYGGTPGHWIEWGRLMLHLHAALEARFETPPAWLLE
                     DAKGLFHATIRDAWAPDGADGFVYSVDWDGKPIVRERVRWPIVEAMGTAYALYTLTGD
                     SQYEEWYQKWWDYCIKYLMDYENGSWWQELDADNKVTTKVWDGK"
     gene            17155..18011
                     /locus_tag="OPY25_002670"
                     /pseudo
     CDS             17155..18011
                     /locus_tag="OPY25_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462900.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
     gene            18055..20091
                     /locus_tag="OPY25_002671"
     CDS             18055..20091
                     /locus_tag="OPY25_002671"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCS0928255.1"
                     /translation="MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSAENPCLWIGAG
                     VADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWLVQFSRGATISATLRISADEAGR
                     LTLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
                     SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKTTLRFECADTYIALLEKLTALLGRQPELPDWVYDGVTLGIQGGTEVCQQKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRIKQWKEEGVQFLSYI
                     NPYVASDKDLCAEAARHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKK
                     NMIALGCSGWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEI
                     LFFMRAGYTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGNNWQFDGDAETIAHFARMTTVFT
                     TLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYTLKYQYLLGQDLLVAPVHEQGRC
                     DWTLYLPEDHWVNIWTGEAHHGGEITVDAPIGKPPVFYRAKSEWALLFASLRNI"
     gene            20137..21519
                     /locus_tag="OPY25_002672"
     CDS             20137..21519
                     /locus_tag="OPY25_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928256.1"
                     /translation="MSQTSSNPATIRLPFKEKLAYGLGDLGSNILLDIGTLYLLKFYT
                     DVLGLPGTYGGIIFLIAKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFVLYAAFPVTLL
                     AIANFVGTPFEVTGKTVVATMLFMLYGLVFSMMNCSYGAMVPAITKNPDERASLAAWR
                     QGGATLGLLLCTVGFVPVMNLIEGNAQLSYIFAATLFSLFGLLFMWLCYAGVKERYVE
                     VKPVDSAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPI
                     LLSWMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVAGDLLNYFFGGGSVSFV
                     AFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFF
                     PGWMLTQIGYIPNVVQSAGTVEGLRQLIFIYPCVLAVITIIAMGCFYNLNEKMYVRIV
                     EEIEARKHTV"
     gene            21565..>22910
                     /locus_tag="OPY25_002673"
     CDS             21565..>22910
                     /locus_tag="OPY25_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928257.1"
                     /translation="MSNHDPLTLKLSLREKCAYGVGDFGSNLMLCIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGVLLDSRRNIGAKGKFRPFILYASFPVALVAT
                     AQFFATHFTLPVKTAFATVLFMLFGLFYSLMNCSYGAMVPAITKNPHERAQLAAWRQG
                     GATIGLLLCTVGFMPIQALFTRSPSLGYLVAAVIFSVCGLFSMWWCFSGVKERYIETV
                     PDTHKPSILKSFCAIFRNPPLLVLCVANLCTLAAFNIKLAIQVYYTQYVLNDIHLLSW
                     MGFFSMGCILIGVLLVPDAVKRFGKKQVYLGGLILWAVGDILNFIWGGTSFLFVIFSC
                     IAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFSRKISAALAGFLPGIM
                     LTQIGYIPNIAQSDTTLLGLRQLIFLWPCGLAIIAALTMGFFYKLNEQRFAFIIEE"
BASE COUNT         5428 a         6159 c         6055 g         5268 t
ORIGIN      
        1 ttacaccgtt cagcgacgtc aaccgcgagc gtggtagcag cagaaaccgc aaacaaaatt
       61 tccacaccgc acatcgccga cttctgcacc atttcgtaac tcgcacgact ggaaaccagc
      121 gccgcgcctt gccgccattc ctcaccttcc gtagcgcggc ggccgagcag tttatccagc
      181 gcaacgtggc gtccgacatc ttcatggccc cccgccagtt cacccgacgg catgacccac
      241 gccgcagcgt gcgtacaacc cgtcagctta cccgtcggtt gaaaatcatt cagatgtttt
      301 aacgcgcgat caaggttacc gagattaaac gtttggctaa acggcagcgg ttgcaccggc
      361 ttaccaatgt cattgagctg ttccacgcca cacacgccgc aaccggtgcg tccggccagc
      421 gcgcgacgac gcgctttcag ccccataaat cgacggctgg aaagatcaat ctgcacttca
      481 agtccgttac aggacggcac aacgtccatg ccatagattt cacgcgggct gtcaatgatc
      541 ccttccgaca gagaaaaccc cattgcgaaa tgcgtcagat ctttcggaga ggccatcata
      601 acgacatgcg aaatgccgtt atacaccagt gccactggca cttcctcggc aacatcatca
      661 agttgggagg actgcaaatc ctcgcgtttc cagagtgtca actggcgtga ggttgtgaaa
      721 tcagtcacat ttaggacttc ttcagacagt atattgttca ctttctttta accatataag
      781 aacacacaca ccaacattat ggtattctgt tacaactcct cccggatgga ggaaaattta
      841 tccaattctg aacctttgcg ggcccgtccg caaagaaaaa taacaaccac tccctgagcg
      901 tttcagatag agaaatgtga aagagaagtg acaatgtcga aacaaggagc aaaccatgca
      961 ggtcagcaga aggcagttct ttaagatctg cgctggcggt atggcaggca ccacggcggc
     1021 ggcactgggc ttcgcgcccg gcgtagcgct agcggaaaca cggcaatata aactgctgcg
     1081 cacccgcgaa acccgtaaca cctgcaccta ctgttccgtt ggctgcgggc tgttgatgta
     1141 cagcctcggc gacggtgcga aaaacgccaa agcatctatt ttccatatcg aaggggaccc
     1201 ggatcatccg gtaagccgtg gcgcgctgtg cccgaaaggg gccggtctgg tggactttat
     1261 ccactctgaa agccgcctga aattcccgca ataccgcgcg ccgggttcag ataagtggca
     1321 acagatcagt tgggaagaag cgtttgaccg catcgctaaa ctgatgaagg aagatcgcga
     1381 cgccaactat caggcgcaga acgccgaagg cgttaccgtt aaccgctggc tcaccaccgg
     1441 gatgctgtgc gcttccgcat ccagtaacga gacgggttat ttaacgcaaa aattctcccg
     1501 cgcgctgggt atgctcgcgg tcgacaacca ggcgcgtgtc tgacacggac caacggtagc
     1561 aagtcttgct ccaacatttg gtcgcggtgc gatgaccaac cactgggtcg acatcaagaa
     1621 cgccaacctc gtcgtggtga tgggcggtaa cgccgcagaa gctcacccgg tcgggttccg
     1681 ctgggcgatg gaagccaaaa ttcacaacgg cgcgaagctg attgtgatcg atccgcgctt
     1741 cacgcgtacc gcgtcggtgg ccgattttta tgcgccaata cgctctggta ctgacattgc
     1801 cttcttgtca ggcgtgatgc tgtatctgct gaccaacgaa aaatacaacc gtgaatacac
     1861 cgaggcctat accaatgcca gcctgatcgt gcgtgaagat tttggcttcg atgatggtct
     1921 gttcaccggc tatgacgcag acaagcggca gtacgataaa accagttggc actatgagct
     1981 ggacgaaaac ggttttgcca aacgcgatac gacactgcaa cacccgcgct gtgtctggaa
     2041 tctgttgaaa cagcatgtct cacgctatac gccggacgtg gtagaaaata tctgcggtac
     2101 gccgaaagcg gacttcctga aagtgtgcga gtacattgca gaaaccagcg caaaagataa
     2161 aaccgcgtcg ttcctgtacg cgctgggctg gacgcagcat tccatcggcg cgcagaacat
     2221 ccgtactatg gcgatgatcc agcttctgct cggtaacatg gggatggcgg gcggcggcgt
     2281 taacgccctg cgcggtcact ccaacattca gggactgacc gacttaggac tgctgtcgca
     2341 aagtctgccg ggctatctga cgctgccgag cgaaaaacag accgacctgc aaacctatct
     2401 ggctgccaat acgccgaagc cattgttgaa ggatcaggtc aactactggg gcaactatcc
     2461 gaaattcttc gtctcgatga tgaaggcctt ctttggtgat aaagcgacag cggaaaatag
     2521 ctggggcttc gactggctac cgaagtggga caaagggtac gatgtactgc agtacttcga
     2581 gatgatgaaa cagggcaagg tcaacggcta tatctgccag ggctttaacc cggtggcttc
     2641 attcccgaac aaaaacaaag tggtcgcgtc gctttccaaa ctgaagtacc tagtgactat
     2701 cgatccgctc aacacggaga cctccacctt ctggcaaaac cacggtgagt cgaacgatgt
     2761 tgatccgtca aaaatccaga ccgaagtgtt ccgtctgcct tccacctgtt ttgccgaaga
     2821 gaatggttcg atcgtcaact cgggtcgctg gctgcagtgg cactggaagg gcgcggacgc
     2881 cccgggaatt gccatgaccg acggcgaaat cctcgccggt atcttcttac gcctgcgtaa
     2941 gatgtactct gaacagggcg gcgccaaccc ggaacaggtg ttgaatatga cctggaacta
     3001 caccaaaccg tacgaacccg cctctgaaga agtggcgatg gaaagtaatg gtaaagcgct
     3061 ggccgatctt atcgacccgg caaccggcgc ggtggtagtg aagaaaggtc aacagctcag
     3121 ttcgttcgcg caactgcgtg atgacggtac gacgtccagc ggctgctgga ttttcgccgg
     3181 tagctggacg ccggaaggca acatgatggc gcgtcgtgat aacgccgacc cgtctggtct
     3241 cggcaacacg ctgggctggg catgggcatg gccgcttaac cgccgtattc tgtataaccg
     3301 cgcttccgcc gatccgcagg gtaacccctg ggacccgaaa cgtcagctac tgaaatggga
     3361 aggcggaaaa tgggccggat gggatattcc ggactacagt gccgctgcgc caggcagcga
     3421 cgtcggaccg tttatcatgc agccggaagg gatgggtcgc ctgtttgcta tcgataagat
     3481 ggcggaaggg ccgttcccgg aacactacga gccgtttgaa acgccgctgg gcactaaccc
     3541 gctgcacccg aacgttatct ctaaccctgc cgcccgtatc tttaaagacg atgccgacgc
     3601 gctgggtaaa gcggataagt tcccgtatgt cggaaccact taccgtctga ccgagcactt
     3661 ccactactgg accaagcacg cgttgcttaa cgctatcgcc cagccggaac agtttgtgga
     3721 aattggcgag aagctggcga ataagctcgg tatcgcgcat ggcgataccg tgaaggtctc
     3781 ctcgaaccgc ggctatatca aagccaaagc ggtggtgacc aagcgtattc gcacgctgaa
     3841 agcggacggc aaggatatcg ataccatcgg tattcctatt cactggggct acgaaggcgt
     3901 ggcgaaaaaa ggttttatag ccaatacgtt aacgcctttc gtcggcgatg cgaacacgca
     3961 aacgccggag tttaaatcct tccttgtgaa cgtggaaaag gtgtaacgga gacgacctat
     4021 ggcttatcaa tcgcaagaca tcattcgtcg ttccgccact aacggtttca cccccgcgcc
     4081 ccaggcgcgg gaccaccagg aagaggtggc gaaactcatc gacgtcacca cctgtatcgg
     4141 ctgtaaagcg tgtcaggtgg cgtgctccga gtggaacgac atccgtgatg aagtgggcaa
     4201 taacgtcggg gtgtatgaca acccggcgga cttaactgcg aaatcctgga cggtgatgcg
     4261 cttctcggaa gtggaacaga acgacaaact ggagtggctg atccgtaagg atggctgtat
     4321 gcactgcgcc gatcccggct gcctgaaggc ctgtccggcg gaaggggcga tcattcagta
     4381 cgctaacggt attgtcgact tccagtccga gcagtgtatc ggctgcggct actgtatcgc
     4441 tggctgcccg ttcaacgtgc cgcgcctcaa cccggaagac aaccgcgtct ataaatgtac
     4501 gctgtgcgtt gactgtgtgg tggtcggcca ggaaccggcc tgcgtgaaga cctgtccaac
     4561 cggcgctatt cattttggct cgaaagagga tatgaaaacg ctggcgggcg agcgggtggc
     4621 ggaactcaaa acccgtggtt atgacaatgc gggtctgtac gatccggcgg gcgtaggcgg
     4681 tacgcatgtc atgtacgtgc tgcatcatgc cgacaagccg aatctgtatc acggtctgcc
     4741 ggagaacccg gaaatcagcg aaaccgttaa gttctggaaa ggcgtctgga aaccgctcgc
     4801 cgcgttcggt tttgccgcga cctttgccgc cagcgtcttc cactatgtcg gcgtcggccc
     4861 gaaccgcgcg gaagaggaag atgacaacct gcatgaagag aaagacgagg tgcgcaaatg
     4921 aaacgacgtg acaccatcgt gcgctatacg gcgccggaac gcatcaacca ctggatcgtc
     4981 gccttctgct tcgtgctggc ggcggtgagt gggctgggct ttttattccc atccttcaac
     5041 tggttgatgc atatcctggg caccccacaa ctggcgcgaa ttctgcaccc gtttgtgggc
     5101 gtggttatgt ttgcctcgtt catcatcatg tttttccgtt attggcacca caatctaatc
     5161 aatcgggatg atatcttttg ggcaaagaat attcgtaaga tcgtcgtcaa cgaggaagtg
     5221 ggtgacaccg ggcgttataa cttcggtcag aaatgcgtat tctgggcggc gattatcttc
     5281 ctggtgctgc tgctggtgag cggggtaatt atctggcgtc cgtactttgc gcctgctttc
     5341 tcaatcccgg tgatccgatt cgcgttaatg ttgcattctt ttgccgcagt agcgttaatt
     5401 gtggttatca tggtgcatat ctacgccgcc ctttgggtga aaggcaccat taccgcgatg
     5461 gtggaaggct gggtaacccg gtcgtgggcg aagaaacatc acccacgctg gtaccgagaa
     5521 gtccgcaaga caacggaaaa agaaactgaa tgagtattcg cataatcccg caagatgagc
     5581 tggggtcgag cgagaaacgt acggcggata tgattccgcc gttattgttc ccccgactca
     5641 aaaacgtcta caaccgccgc gccgaacgtc tgcgcgagct ggctgaaaat aacccgctgg
     5701 gcgattacct gcgctttgcc gcgcttatcg cgcacgcgca ggaagtggtg ctgtacgacc
     5761 atccgctgga gatggatctg accgcacgca ttaaagaagc gaacgaccag ggcaagccgc
     5821 cgctggatat ccacgtgctg ccgcgtgata agcactggca aaaactgctg cattcgttaa
     5881 ttgccgagct aaaacccgag atgaacggcc ccgcgctggc ggtgattgag aacctggaga
     5941 aagcctcaga gcaggagcta gagcagatgg ccagcgcgct gtttgcctcg gattttgcct
     6001 ccgtcagcag cgataaagcc ccgtttatct gggccgcgct ctccctttac tgggcgcaaa
     6061 tggccagctt gattccaggc aaagcccgcg cggaatacgg tgaagcgcgc cagtattgcc
     6121 cggtatgcgg ttcgatgccg gtctccagca tggtgcaaat cggcaccacg caggggctgc
     6181 gttatctgca ctgtaacctg tgcgaaaccg aatggcacgt cgtgcgcgta aaatgcagta
     6241 actgcgaaca gagccgcgac ttacactact ggtcgctgga aaatgagcag gctgcggtga
     6301 aagccgaaag ctgcggcgat tgcgggactt acctgaagat tctctatcag gaaaaagacc
     6361 cgaaagtgga agcagtggcc gacgacctcg cctcgctggt gctggacgcg cgcatggaac
     6421 aggagggctt cgcccgaagc tctatcaacc cgttcctgtt cccgggggaa ggggaataag
     6481 ttttttactc agaccgggcg aagtttgccg tccggtctac aagtgatacg gcgtgatcac
     6541 tcccggaata tcggcaaagt cttttgtatt gcgcgtcaca agctcacaac gatggacttg
     6601 tgcagtggcc agaatgatcg catccgggag tttcatgcca tactcctgcc tgacaatgac
     6661 gcttcgttcc gcgatttcct gtgttacgcc aataatattg aacgcactta atgcaatgcg
     6721 cgtgcggttt tcctgatgat atttcttagc acccaccatc acttccatcc atgtgataag
     6781 gctaatcgca ttttgtggcg gatacgcttc cagcgcatgt ttcgcttcaa ttcgaccgct
     6841 aaacaggtcg atgaggatat tggtatcaaa aagcgcagac cctttgacca ttaccattcc
     6901 tcacgaagtt tacgttggta ttcaacgcca tcttcctcac agccttgcca gagccccaat
     6961 gctttcgaaa ttgtggtctc agcccgatcc tgtctttcca gatactgctc aacggcctcc
     7021 cgcaagagtt ctgcacgagg taggttgcgt tgcaccttga gatcgtcaag ccgtttaatc
     7081 acatcgtctg ataaatcgag taaaattctg cccatatcca tcccagccat catactcaca
     7141 tatacctcca gtatatcatt cgcgcttatt tttcaaacaa catacacctg agactgacga
     7201 gaaaatagtt attacgcgaa cgatttttat ttttgcgagc cgctttccag aatcgtacgc
     7261 agcccaattt tcccattttc attcgaacca aatcgagtta taaaactgta tatccataca
     7321 gataaaggca atgaaaaatg gcactggaaa gcgggattgc gcagttagtg gaggaattta
     7381 tcgcggcggg acgcccctct tctcgcgaac agaatattga tgaccggagg gcgggctaca
     7441 tcgctagcac gacattggca ggagaaacag aaacccgcgt ccaggttgaa gatattgaac
     7501 tcgatgccat gacgtttcgc gtggtttcgc cgctcaatgc cacagggaaa ttaccctgca
     7561 tcatttatta tcatggtggc tgctttgtca gcggcggttt tgccactcac gataaccagt
     7621 taaggcagtt agctttttac agccgttgtc gcgtgattgc ggcacagtac cgacttgcac
     7681 cagagcacac cttcccggcc gcacataacg atgccgaaac cggagccaat actatctgga
     7741 aatatgccca gaaactgggg atagatcgcg agaacattac gcttgctggt gacagcgcgg
     7801 gtgggcatct ggcgctggtc accgcgctac gcctgaaagc cgcccgtcaa tggcaacctg
     7861 cacagctgat tctgatctac cccatgctgg acgcaaccgc caggtttgcg agctacacct
     7921 gtaatgggct ggattacatt atcacgcgtg acacgctgct ttcaggctac gagatgtata
     7981 tgccgcgaac cgatccactg catcctgaag ccagtccgct ctggcgtgag gacttcgccg
     8041 gtctgccatc cacgcacatc attactgccg aattcgaccc actgcgcgat gagggcgagg
     8101 ccctgtatca acggttccag gaacagggtg tggaatgcac ttgccagcgc tatctcggcg
     8161 ttatccacgg gtttttccaa ttgggcggag tgagcaagac ggcgcgggac gcaatacgcg
     8221 acgtggcctg gcgtgttgta agtccatcaa caagcaaaat gacctaaaat tcaattttgt
     8281 tttcaacttg aaaactggat aacgttgcgc taaattgttt tcaggttgaa aactttgtaa
     8341 tggaactaca ttgtgcatgt tatcagccga aaactgttca atgaagcgat gctcatgtat
     8401 ccaaaccatg agcttgctct cactgagttg ctgaatgttc tggagaaaaa aacattcact
     8461 cagcctgaag agatgaagcg gtatattcct tcgctggata attttaagta cagagataaa
     8521 tggtgggtga ttgatgtttc tggtaacagc ctgagactca tttcctacat agatttcagg
     8581 ttacataaga tatttgtgaa acatatcgtt tcccatgccg aatatgacaa actgaccgca
     8641 tattatcggg gtaatgaaga atgagaactc atcgtcagat ggatgcaacc agcgcaaaaa
     8701 agatcgttga taccttcagc gatgcggtaa aaagcgtccc actgatgggg gaagaccgaa
     8761 atgacaatga gtatcgcagg gcactagcgc tagtggagtt tctggtcgac cacgacgatc
     8821 ttgaaaaccc actatttgaa ttgctctgtg cccgaatcag tgaatacgaa aaacatgcgc
     8881 cggaattcaa agcactcaac caacacctgg agaaaacgcc ccctggcgtt tcagtattgc
     8941 gaacgctcat ggatcaatac ggtctcaaag cagcagatct tgccaacgaa cttggttcta
     9001 aatcgaacgt cagcaacatc ttaaatggcc gcagagcact aacggttaat catattaaag
     9061 cgcttacaca acgctttaaa ctaccagcgg atgccttcat cgagtagttg gatatgtcca
     9121 gctactcttc ctcattcccg ccctcttcat acgggccgaa cggtttcgca ggtagtacga
     9181 tataaatgcc ttcgaaaatt gccccggcgg tctcgccgcc caacagttca acctgcaact
     9241 ggacacgcgc ttttttaccc cgcgccagcc tgtccaaatc accgcttagc gaccccaaat
     9301 cagccacggc gtttggcttt ccgctaatgg gtttactgta gcgaatatgg gcgtcagcaa
     9361 gaataatcgt cccgcccagg tggcgttcac ggagcatcag ccagataagt ccccatccgg
     9421 tcagcgtcgc cagggagaac aggctgccgg caaacaccgt gtgatgcgga ttttgattac
     9481 cggtttccgg catcgtggtg ataaattttt gcccggtgta ctgctgaatg cgcaccccca
     9541 tcttttcact caatggaatg tgctcatacc aggcctgctg aagctgcccg caccaatcgc
     9601 cgcgatgcag gatatcatcc agcgatgcta ccggtttaat catcagaaaa tggcggattg
     9661 gcgtggttgt gggcgtagta atctccccct gattgacaaa cccgagtttg gcaaagaact
     9721 caaccgcatc ttcgcgcgcg ctgcaggtga cgcgcttaac gccttcctgg cgggcgacag
     9781 actccagggt catcgccatt aatgtcccca gccctttatc ctgtaccgag ggatgtacag
     9841 ccataaaacg gatagacgcc tcgttatctg cattgatata caggcggccc actgcaacta
     9901 agtttccttc ttcgtccacc accatttgat ggtgcgccaa cgcatcccag ccatcccgtt
     9961 ccgacccttt cggctggtgc agcggtttac gcagcatctc ccagcgaaac tggtagtaac
    10021 gttctaattc ttcttctgtt tgcggaactc gaaggtgata catagccgta ctctctcttg
    10081 ttatccgcgg ccacgccgga agctgactca tacctggagc cagaatgtca cgggaccgtc
    10141 attaaccagc tcaacctgca tatcggcagc gaagcgtccg gtttgcgtgt ttatcgcctg
    10201 ctggcggcag cgttcgacaa aatattcata aagcgcctgc gcgcgatccg gcgcagcccc
    10261 gccggaaaag cttggccgca taccgcgttc ggtatctgcc gccagcgtaa actgcgacac
    10321 caccagcacg ctgccgccag cctgttgtac attcagattc atcttgccgt caacatcgct
    10381 gaagatacgg tatcccagca cgcgctcgca cagacgattc gctttttgtt cgtcatcttc
    10441 tttttcgaca cccaataaca ccaaaagtcc tgggccgatt ttacccgtca cctcgtcctc
    10501 cacggtgacg ctggcacggg ttacgcgttg aattaatgca atcatggttg gtcagcttct
    10561 tcttgttctg cggcttgttt gagttttcgg tattccccga gagtgacagt tatttctgcg
    10621 ccaagcaaga ctatacacca ggtccagtat acccagacaa acaggatagg gatcactgcc
    10681 agtacgccat aaatgagctg atatgacggg aacatggtga tataaagcgc gaaacctttc
    10741 tttccggcct cgaacagcaa cgctgcgaca aacgcgccga caagggcgtc acggttcggt
    10801 acgcgagttg ttgggacaat actgtaaagt aaccagaatg agatccacga gagcagcagc
    10861 ggaaggatgc gcaatacatt gtcgatgacc gtattcagat cgctggccca gcgtaaagaa
    10921 agcagatagg agctgatcgc cagactggca ccggcgagaa gcgggccgag cgtgaggatc
    10981 atccagtaca ccgcaaaaga gtacactttt gggcgtgtgc gtttgctgcg ccagatagtg
    11041 tttaaggcgc tatcaatggc gtacatcaac agcaatgccg tcacaatcag tccacaggcg
    11101 cccaccgccg tcattttgtt ggagttagcg acaaactgct caatatagcg ctgaatcacg
    11161 tctccggtgg ctggcataaa gttagcaaaa ataaaatggc gtaactgaat gctgacatca
    11221 gaaaacatcg gaaaagcagc gaaaagggca aaaacgacgg caataagcgg tactaaggag
    11281 agtaatgaga cataggcgag gtttcccgcc agagtcgtca tattatcctc atcgatacgc
    11341 tgccataata gcttgagcca ggcccgaaca gggcgcgtat ggcgtccagc tttttggtga
    11401 acggttttta gcataacagc ttcgcgaaat agtcagggat ggtggcttta tccttcacca
    11461 gaatgctggt gatccccaac tggttggccc cttctatatt atcggcattg tcgtcgaaaa
    11521 agaccgcatc ggcagcggaa aaaccttctt tctgcaggac gtgctgataa atacgcgctt
    11581 ccggtttacg cattcccaaa tcctgcgata aatagatatg gtcggcggca gcgcgcacct
    11641 ccgggtattc ctccggccag aagtgggtat gcagtcggtt agtattggat aacaccacca
    11701 cgcgatgccc ctgctcgcgc agtttatgca tgatagcaat cacttcgggc cgtaatccga
    11761 caaataccgc ctgccagccg tgcgcaaatt gttcataact gagcgataac gccatttcat
    11821 gacagaaagc ttcagcaaac gcttcgtccg ttatctcacc gcgttcatgt tggtgaaaag
    11881 tctcgcccat cgtaaatttt tgcttcagcg aagccaacgg tactcgactc aggtcgctcc
    11941 acacacctaa tacgcggtta aagtcgatat cgacaatcac attacctaaa tcaaagatgt
    12001 agagcatgtc attctccttg ctaaccgggg atgaataact gtagcgggaa aggagaagtt
    12061 tgactatgta tccctttata aatcaattaa caaaaagaca atagaaacgc agacgatgcc
    12121 caatatcgcc tgcatcacag cgccgtttta ttggccggat aaagcgctga cgcgaccctc
    12181 cggcgcaagg gcgcttgtca cgctgaaacg gcgtcgtcca gcgaaggact cacctgaacc
    12241 acttcgattt gctgggattg aagtaaattc tgtaatgccg gaccgggata ctcgtccgta
    12301 aacagagcgg taatctgtga cacattgccg atctcaaccg ccgcagaagc atggtatttc
    12361 gtatgatcgg cggccagcag aatatgtcgc gagtgagcca tcatggtttt cactacgctg
    12421 gcttcgttga catcaaactc cagtaacgcg ccatcgctct ctatcgcgcc tacgctggtg
    12481 acgagatagt ccgcccggaa ccccgccaca aacgccgccg cggatggccc gataatgccg
    12541 ctattatgcg ggcgcagcgt gccgccaggc accatcactt caaagcgagg gttattataa
    12601 agaatgtgcg cgacgcgcag gctattggtg ataatgcgca gatgattatg gttgagcagc
    12661 gcgcgcgcca cctgctcaac cgtcgttcca atcgtgataa atatcgtgga gccatccgga
    12721 atatagtcag ccacggcttc cgcaatggct tttttctctt gcgtccagga gatctctcgc
    12781 tgctcaaagg cggtattgac cacactggac gctctgccag cgccgccgtg atgacgcgta
    12841 atcagcccct gctcgcttaa tttacgaata tcgcggcgaa ccgtctgggt agagacctcc
    12901 aacaaactgg ctaactcatc gatattcata tagccgcgct catcaataag cattaacagc
    12961 cgatcgtgtc gcggattacc ggtcagttcg gtaagactca tgagcattcc tctaaaagct
    13021 tcctactgct catattatac aaaaagtgac aagaaagatc gggtttgctc acaatcaggg
    13081 atacccgccc ggccacccgg gcgcgtacac ttcagcgcgg caacgccgct ggcgaatctg
    13141 acagcctctt cgatagcgta tccgcttgcc aggccaaatg ccagtgcgcc atgaaaaaca
    13201 tcgcccgcgc cggtagtatc caccacctcc acggtaaaac ccggttggtg gcgtaccgcc
    13261 gctttttcca accagttgca gccttcgctg cctcgcgtga catagacatg tccatttgtg
    13321 agcatttgtg ctttttttag cgcatcaatg gcttcgctca tccccgtcag gcgtgccagc
    13381 cccggctcgg agaaggcggc gtggtcgctt aacgccacca gctcgctaat atcctgcggc
    13441 gtaatatcgc catcaagaac agtcatgacg ccagcctgac gcgccagcgt aaacgcctgt
    13501 tttgcgccgt catgccagcg cacatccgcc aacaccacat cccactgcga aaaatcgatg
    13561 tcgttaagcc agtcggcgtc aggtaataaa tccgggctgg gataattaac gataatccgc
    13621 tctcctttgg catccaccat aatcgctgac tgcgacgaca tggcctgcgt gtagcggcgg
    13681 gtatagcggg tatttacccc cagggattcc agttccgcca gcaggctgtt tccggtgtcg
    13741 tcatcgccca cacggccaat aaagtccacc tgcgcgccca atttcgccgc agccacggca
    13801 gcggtcgccg caggcccgcc gcccacttcc gtatagcgct tcgccacata tttgccccct
    13861 tctgttggta atccttccac gtaatagatg cgatccatca cggtaatacc tacacaagca
    13921 atacgaacca tggtcattcc tcaagcattt tcgatgtgct cattttaatt tcacgaaatg
    13981 tttaaaaagt gacggctgtc aattttttga ccataaatta caaatacgat cacaaacaga
    14041 cagaaaaagg ctcattaatg acaaaaaatg acaccaccgt gttcaggaga acgatatggc
    14101 agttatagca tttatcgggt tgggacagat gggctcccct atggcgagca atctgctaaa
    14161 gcagggccat caactcagcg tcttcgatat taatcccgac gccgtacagc gtctggtaga
    14221 caaaggcgcg caacctgcaa gcagcccggc tcagacaacc atcggcgctg aatttgttat
    14281 caccatgctc ccgaacggcg atctggttcg ttccgttttg tttggcgagc aaggcgtttg
    14341 tgaaactctt tcccgtgaag cgctggtcat tgatatgtcc actattcatc cgttgcaaac
    14401 cgataagctg attgccgaca tgcagagcaa agggttcagc attgatggat gtgccggtag
    14461 gccggacatc cgacaacgcg attaccggca cattgttgtt gctggcaggc ggtacgacgg
    14521 agcaagtaga gcgcgctacc cctgttctga tggcgatggg taatgagctg gtcaacaccg
    14581 gcggcccggg aatgggtatt cgcgtaaaac tgatcaacaa ctacatgagt attgcgctaa
    14641 atgcgctctc cgccgaagcc gccgtgctgt gtgaagcgct ggggctttcc ttcgacgtgg
    14701 ctttaaaagt gatgagcggc actgccgcag gcaaagggca tttcaccacc acctggccga
    14761 ataaagtgat gaaaggggat ctgtctcccg ccttcatgat cgatctggcg cacaaagatc
    14821 ttggcatcgc gttggatgtc gccaatcaac tgcacgtacc gatgccgctc ggcgccgcct
    14881 cccgtgaagt ttataacctg gcgcgggccg caggccgcgg tcgggaagac tggagcgcca
    14941 tcctggaaca ggtgcgcatc agcgccgggc tgactgccaa cgtaaaaaag taacgactgt
    15001 ataaaggaaa attgaatgaa caactacacc atcaaagaca ttacgcgagc gtccggcggg
    15061 tttgccatgc tggctgtcga tcagcgcgag gcgatgcgtt taatgtttgc tgctgctggt
    15121 gcgaaaacac ccgttgccga tagcgtgctg acggatttca aagtgaatgc ggcgaaaatt
    15181 ctttccccgt atgcctctgc cgttctgctg gatcagcagt tctgttatcg ccaggccgta
    15241 gaacaaaacg cggtcgctaa aagctgcgcc atgatcgtcg cggcggatga tttcatccca
    15301 ggcaacggta ttcccgttga taacgtggtc attgataaaa aaattaatgc gcaggcggta
    15361 aaacgggatg gcgcgaaagc cttaaaactg ttggtgctgt ggcgcagcga tgaagacgcg
    15421 cagcagcgtc tggatatggt taaagaattc aatgaattat gtcactccaa tggtttgctg
    15481 agcattatcg aaccggttgt acgtccgccg cgctgcggcg acaagttcga tcgcgagcag
    15541 gcgattatcg atgcggccaa agagctgggc gacagcggcg ccgatcttta caaagttgaa
    15601 atgccgctct acggcaaagg cgcgcgttcc gatcttctta ccgcctcaca acgcctgaat
    15661 gggcatatca atatgccgtg ggtcatcctc tcttccggtg tggacgaaaa actgttccct
    15721 cgcgcagtca gggtcgccat ggaagctggc gcatccgggt tcctggcggg acgcgcggtc
    15781 tggtcatcag tgattggttt accggatacc gagctgatgc tacgtgatgt ttccgcgcct
    15841 aaattgcaac gtctgggcga gatcgtcgat gaaatgatgg caaaacgtcg ttaatacgag
    15901 gatgaaagaa tgaaatggtt taacacgttg agccacaacc gctggctgga gcaggaaacc
    15961 gaccgcatct ttaatttcgg taaaaacgcc gcggtgccga caggcttcgg ctggctggga
    16021 aataaagggc aaatcaaaga agagatgggc acccatcttt ggatcacggc gcgtatgctg
    16081 cacgtttatt ccgtggcggc gtcgatgggc cgaccgggcg cttatgatct ggtcgatcac
    16141 ggcatcaaag ccctgaacgg cgcgctgcgc gataaaaaat acggcggctg gtatgcctgc
    16201 gttaacgatc agggcgtggt ggatgcctct aaacagggtt atcaacactt cttcgccttg
    16261 ctgggtgcgg ccagcgccgt cacgaccggg caccctgaag ccagaaaatt gctggattac
    16321 accatagaag tgattgagaa atacttctgg agtgaagaag agcagatgtg ccttgagtcc
    16381 tgggacgaag cctttagcca gacggaagat taccgtggcg gtaacgccaa tatgcacgcc
    16441 gtcgaagcgt tcctgattgt ttatgacgtt acccatgaca aaaaatggct ggatcgcgct
    16501 atcagaatcg catcagtcat tattcatgat gtagccagaa ataatcatta ccgtgttaat
    16561 gaacatttcg attcacagtg gaaccctatc cgcgactaca acaaagataa tcctgcccac
    16621 cgtttccgcg cctacggcgg tacgccaggt cactggattg agtggggccg tctgatgctc
    16681 catctccatg ctgcgctgga ggcccgcttc gaaacgcccc ccgcctggct gctggaggat
    16741 gcgaaaggtc tgttccatgc cactatccgc gacgcctggg cgccagatgg cgcagacggt
    16801 tttgtctact cagtcgactg ggacggtaaa cctatcgtac gtgaacgcgt gcgctggccg
    16861 attgtggaag cgatgggtac ggcctacgcc ctctacaccc tgacgggcga tagccagtat
    16921 gaagagtggt atcagaaatg gtgggactac tgcattaagt acctgatgga ctatgaaaat
    16981 ggttcctggt ggcaagagct ggacgccgat aacaaagtga ccaccaaagt gtgggacggc
    17041 aagtaagata tttaccatct gctgcactgc ctggtcattc ctcgtctgcc actggcgccg
    17101 ggcctggctc cggcggtcgc ggcgggtctc ctggatatca acgcgaaata ggtcatgagg
    17161 atggcagcca tgcacagcgg tggaaaaact attcagctta atgcgggcca ttaccaggcg
    17221 aaaatcgtca cggttggcgc aggtctggcg gaactgactc atcatggacg tcatgtggtc
    17281 atcccgcata aaccggaaga aatacccatg gcgcatctgg ggaaggtatt gattccctgg
    17341 ccaaatcgcg tgacaaatgg ctgctactcc tataacggca aagttttcca gcttgccgtt
    17401 aacgacccgg tttcgcagac cgccattcac ggtctgttag cctggcgaga ctggcagatt
    17461 aattatcagt cggcgacgga agcgtcgcta acgatttttc tgccgccctc ttacggctat
    17521 ccctttgcgt tgatatcgga agtgatttat cggttagatg ccgccagtgg gctgcacgta
    17581 ttgattcgta cgcaaaacat tggcgatgaa tcagcccctt atggcgcggg cgcacatcct
    17641 tatttgactt gtaatctgca aagcatcgat agctgtgtat taacactgcc tgcaagcgaa
    17701 gaattgcccg caggcaggaa tttttccgca tcatgcctgc tcggcgaaac gcgccttgat
    17761 catgcggtta agaccgcgac tgccccggcg gagtgggagg tcagacttac cagcccaacg
    17821 cagaacatgt ctacattttt acgcagcaag caaccctggc tacagatcta taccggcgaa
    17881 aaactcagcc gaaaggtctc gcggtagagc ctatgagctg cccgcccgat gcatttaatt
    17941 ccgggatcgc actgattcat cttgccccaa aagcgatcca tcaactgcat ttttccatcg
    18001 gctgcgacta gcccaaatgg attaccgaat taccctacat tcacggagat tacaatgaat
    18061 tctctaccac aacggtcaac cgattttgaa ctgacaacat cacaggatgg ttttgcgctt
    18121 agctggcaac agcgcctgat tttacgccac agcgccgaaa acccctgtct gtggattggc
    18181 gcgggcgttg ccgacattga catgtttcgc ggcaacttca gcatcaaaga caaacttaac
    18241 gagaagattg cattaacgga ggccaccgtc agcgagctac ccgacggctg gctggtacaa
    18301 ttcagccgtg gcgcaacaat tagcgccacc cttcgcatct ccgccgatga ggcgggacgc
    18361 ctgacgttgg atctgcaaaa cgacgacctg caccataacc gtatctggtt acgcctcgca
    18421 gctaatccag acgaccatat ctacggctgc ggcgaacagt tctcttattt cgatttgcgc
    18481 ggcaagccgt tcccgctgtg gaccagcgaa cagggcgttg gccgtaataa aaccagctat
    18541 gtcacctggc aggcagactg taaagagaac gccggcggcg actattactg gaccttcttc
    18601 ccgcaaccga cctttgtcag cacgcagaag tattactgcc acgtcgataa tagctgctat
    18661 atgaatttcg acttcagcgc gccggagtat cacgaactgg cgctgtggga agataaaact
    18721 acgctgcgtt ttgagtgtgc cgacacctac atcgccctgc tggaaaaact gactgcgctg
    18781 ttaggtcgcc agccggagct gccggactgg gtttacgacg gcgtcacgct cggcattcag
    18841 ggcggtacgg aagtttgtca gcaaaaactg gataccatgc gcaacgcagg cgtaaaagtg
    18901 aacggtattt gggcgcagga ctggtccggt atccgcatga cctcctttgg caagcgcgtg
    18961 atgtggaact ggaagtggaa tagcgacaac tatccacagc tggatagccg gatcaaacag
    19021 tggaaagaag aaggcgtcca gttcctctct tatatcaacc catacgtcgc cagtgataaa
    19081 gacctctgcg ctgaggcggc gagacacggc tatctggcga aagacgccac gggcggcgac
    19141 tatctggtcg agtttggcga attctatggc ggcgtggtcg atctgactaa tcctgaagct
    19201 tacgactggt tcaaagatgt catcaaaaag aacatgatcg cgctcggctg cagcggctgg
    19261 atggcggatt tcggcgaata tctgccgacc gacacgtatc tgcacaacgg cgtcagcgca
    19321 gagatcatgc ataacgcctg gcccgcactg tgggcgaagt gtaactacga agcgctacag
    19381 gagaccggca agctcggcga gatcctgttc tttatgcgtg cgggttacac cggcagtcag
    19441 aaatattcca ccatgatgtg ggcaggcgac cagaacgttg actggagtct tgatgatggt
    19501 ctggcctctg tcgtgcctgc tgcattgtcg ctggcgatga ccggccatgg tctgcatcac
    19561 agcgatatcg gcggctacac caccctgttt gacatgaagc gcagcaaaga gttgctgctg
    19621 cgctggtgcg atttcagcgc ctttacgccg atgatgcgca cccatgaagg caaccgcccc
    19681 ggcaataact ggcagttcga cggcgacgcg gaaactattg cccactttgc ccgcatgacc
    19741 accgtcttta ccacgctgaa accgtatctc aagcaggcgg tggcgcaaaa cgcggctacc
    19801 ggtctgccgg tcatgcgtcc gctattcctg cactacgaga acgatgccgc tacctacacc
    19861 ctgaaatatc aatatctgct cggtcaggat ctgctggtcg cgccggttca cgagcagggg
    19921 cgttgcgatt ggacgctgta cctgccggaa gatcactggg tgaatatctg gaccggcgaa
    19981 gctcaccacg gcggtgaaat taccgtggat gcgccgattg gcaagccgcc ggtcttctat
    20041 cgcgcgaaga gcgagtgggc tttacttttt gcttctttac ggaatatcta atacggctcg
    20101 cccgcaggga aacttgcggg cagatggaga agaataatga gtcaaacatc atcgaatccg
    20161 gcaaccatac gcttgccgtt taaagaaaaa cttgcctatg gactggggga tttaggttcc
    20221 aatatcctgt tagatatcgg gaccctctat ttactcaaat tttataccga tgtgctgggt
    20281 ttaccaggga cttacggcgg gatcattttc ctgatcgcca aattttttac cgcatttacc
    20341 gatatgggta ccggcattat gctcgactcg cggcgtaaaa ttggtccgaa gggcaaattc
    20401 cgcccgttcg tgctttacgc ggcatttccg gtaacgctac tggcgattgc taactttgtc
    20461 ggcacaccgt ttgaggtgac gggaaaaacc gtcgtcgcaa cgatgctgtt tatgctgtat
    20521 gggctggttt tcagcatgat gaactgctcg tatggcgcga tggtgcccgc gattaccaag
    20581 aacccggatg aacgcgcctc gcttgccgcg tggcgtcagg gcggcgccac tctcggcctg
    20641 ctgctgtgta ccgttggctt tgtgccggtc atgaacctga tcgaaggcaa tgcccaactc
    20701 agctatattt tcgccgccac gctattttca ttgtttggcc tgctatttat gtggctgtgc
    20761 tacgccggcg ttaaagagcg ctacgttgaa gtgaaacctg tcgatagcgc gcaaaagcct
    20821 ggattattgc agtcgttccg cgccatcgcc ggtaaccgcc cgctgtttat tctgtgtatc
    20881 gccaaccttt gtactctcgg cgccttcaac gtcaaactgg cgattcaagt ttattacaca
    20941 cagtacgttc ttaacgaccc gatcctcctc tcctggatgg gcttctttag catgggctgt
    21001 atttttatcg gcgtcttttt gatgcccggc gcagtcaggc gttttggcaa gaagaaagtc
    21061 tatatcggcg ggctgttaat atgggtggcg ggcgatctgc tcaactactt ctttggcggc
    21121 ggctcggtca gttttgtcgc cttctcctgc ctggcgttct tcggttccgc cttcgtcaac
    21181 agcctgaact gggcgctggt ttccgacacg gtggagtacg gtgaatggcg caccggcgtc
    21241 cgctcggaag ggacggttta caccggcttc acgttcttcc gtaaggtctc ccaggcgctg
    21301 gcagggttct tccccggctg gatgctgacg caaatcggtt atatcccgaa tgtggtgcaa
    21361 tcggcaggca ccgtcgaagg cctacgccag ttgatcttta tatatccttg cgtgctggcg
    21421 gtcatcacca ttattgcgat gggctgtttc tacaacctca acgagaagat gtacgtgcga
    21481 attgtggaag agattgaggc ccggaaacat acggtttaac aacaataaaa tataacgccc
    21541 tgcggggcgt tttgagaggc gattatgtct aatcatgatc cgctaacgct aaagttgagc
    21601 ctgcgggaaa aatgcgccta tggcgtgggc gatttcggct caaatctgat gctgtgtatc
    21661 ggtacgctgt atctactgaa gttttatacc gatgaactcg ggatgcctgc atattacggt
    21721 ggaattatct ttctggtggc gaaattcttc actgctttta ccgatatgct caccggcgta
    21781 ttgctggatt cacgccgtaa tattggcgca aaaggaaagt ttcggccttt tattctgtat
    21841 gcgtcatttc cggtggctct ggttgctact gcgcaattct ttgccactca ctttacttta
    21901 cccgttaaaa cagccttcgc gacggtgctg tttatgttgt tcggtctgtt ctacagcctg
    21961 atgaactgct catacggcgc gatggtaccc gctattacca aaaatccgca tgagcgggcc
    22021 cagctcgccg catggcgaca aggcggcgct accattggcc ttcttctttg taccgtaggt
    22081 tttatgccca ttcaggcgct gtttacccgt tccccttcgc tgggttatct ggttgcagca
    22141 gtcatttttt cggtctgcgg gctgttcagc atgtggtggt gctttagcgg ggtgaaagaa
    22201 cggtatatcg aaaccgtacc tgacacgcat aaacccagca tattgaagtc cttctgcgcg
    22261 atttttcgta atccgccgct gctggtgctc tgcgttgcca atttgtgcac gctggctgcc
    22321 tttaatatta agctggccat tcaggtttat tacactcagt acgtgctgaa cgatattcat
    22381 ttgttgtcat ggatgggttt tttcagcatg ggctgtatcc tgattggcgt cttattagta
    22441 cctgatgcgg taaaacgctt cgggaaaaaa caggtttatc ttggtggtct gatactgtgg
    22501 gccgttggcg atatcctgaa ttttatctgg ggcggaacgt cattcctgtt tgttattttc
    22561 tcttgtattg ccttcttcgg taccgctttc gtcaacagcc tgaactgggc gctggttccg
    22621 gatacggttg actacggcga atggaaaacg ggtattcgcg ctgaaggctc ggtgtatacg
    22681 ggttatacct tttcccgcaa aatttccgct gcgcttgctg gctttttgcc aggtattatg
    22741 ctgacgcaaa tcggttatat ccccaacata gctcaaagtg acaccacgtt gcttggtttg
    22801 cgtcagctca tttttttatg gccttgtggt cttgccatta tcgcagcact aacgatgggc
    22861 tttttttata agctcaatga acaacgtttc gcttttatta tcgaggaaat
//
LOCUS       DAJVKX010000068        22197 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000068 DAJVKX010000000
VERSION     DAJVKX010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22197
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.068"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            387..1193
                     /gene="xthA"
                     /locus_tag="OPY25_002674"
     CDS             387..1193
                     /gene="xthA"
                     /locus_tag="OPY25_002674"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCS0928258.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDEMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKATPISVRRGFPDDGEEAQRRIIMAEIPSPLGN
                     ITVINGYFPQGESRDHPLKFPAKAQFYQNLQNYLETELKCDNPVLIMGDMNISPTDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMSRLLKWGLVDTFRQANPQTMDKFSWFDYRSK
                     GFVDNRGLRIDLLLASAPLAERCAETGIDYDIRSMEKPSDHAPVWATFRV"
     gene            1266..1682
                     /locus_tag="OPY25_002675"
     CDS             1266..1682
                     /locus_tag="OPY25_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine (deoxy)nucleoside triphosphate
                     diphosphatase"
                     /protein_id="HCS0928259.1"
                     /translation="MIKKLDVVAAIIERDGKILLAQRPVHADQAGLWEFAGGKVEPGE
                     TQPQALIRELREELGIDATPGVYIASHQRDVSGRRIHLHAWHVPAFNGLIRALEHQAL
                     AWCTPEEALEYPLAPADIPLLQAFMALRDARLTDLC"
     gene            complement(1642..1917)
                     /locus_tag="OPY25_002676"
     CDS             complement(1642..1917)
                     /locus_tag="OPY25_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HCS0928260.1"
                     /translation="MRRSLMVAVMAIMPMVGLANQNSRPDIQVNVPPEVFSTRGQSSQ
                     PCIQCCVYQDQNYSEGAVIKVEGVVLQCQRDEKTISTNPLVWRRVKP"
     gene            2156..3499
                     /gene="gdhA"
                     /locus_tag="OPY25_002677"
     CDS             2156..3499
                     /gene="gdhA"
                     /locus_tag="OPY25_002677"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCS0928261.1"
                     /translation="MDQTCSLESFLNHVQKRDPHQTEFAQAVREVMTTLWPFLEQNPR
                     YRHMSLLERLVEPERVIQFRVVWLDDKNQVQVNRAWRVQFNSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGP
                     DTDVPAGDIGVGGREVGFMAGMMRKLSNNSACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGLGFEGMRVAVSGSGNVAQYAIEKAMAFGARVVTASDSSGTVVDESGFTP
                     EKLARLCEIKASRDGRVADYAREFGLTYLEGQQPWSVPVDIALPCATQNELDVDAARV
                     LIANGVKAVAEGANMPTTIEATDLFLEAGVLFAPGKAANAGGVATSGLEMAQNAARLS
                     WKAEKVDARLHHIMLDIHHACVKYGGDNKHTNYVQGANIAGFVKVADAMLAQGVI"
     gene            complement(3529..5478)
                     /gene="topB"
                     /locus_tag="OPY25_002678"
     CDS             complement(3529..5478)
                     /gene="topB"
                     /locus_tag="OPY25_002678"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCS0928262.1"
                     /translation="MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAG
                     DPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALV
                     TSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSS
                     VHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLSVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAA
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGE
                     KKKSAPRKRAGKKSPPAEETGRQTE"
     gene            complement(5483..6526)
                     /gene="selD"
                     /locus_tag="OPY25_002679"
     CDS             complement(5483..6526)
                     /gene="selD"
                     /locus_tag="OPY25_002679"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HCS0928263.1"
                     /translation="MSKQAIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSIISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINTLSPDIAREVTEGGRFACRQAGIALAGGHSIDAPEPIFGLAVTGVVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNVAGAAFAN
                     IDGVKAMTDVTGFGLLGHLSEMCQGAGVQAMLCYQDIPKLPGVEEYIALGAVPGGTER
                     NFASYGHLMGDMSREVRSLLCDPQTSGGLLLAVTPDAEDDVKATAAEFGIELTAIGEL
                     VEARGGRAMVEIR"
     gene            complement(6644..7195)
                     /locus_tag="OPY25_002680"
     CDS             complement(6644..7195)
                     /locus_tag="OPY25_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HCS0928264.1"
                     /translation="MDALELLVNRRSASRLAEPAPVGEQLQNILRAGMRVPDHKSLQP
                     WRFFVIEGEGRDRFSAVLEQGAVAAGGDEKAIEKARNAPFRAPLIITVVAKCEENHKV
                     PVWEQEMSAGCAVMAMQMAAIAQGFNGIWRSGALTESAIVREAFECRPQDKIVGFLYL
                     GTPQLKASTTISTPDPTPFVRYF"
     gene            7369..9225
                     /gene="sppA"
                     /locus_tag="OPY25_002681"
     CDS             7369..9225
                     /gene="sppA"
                     /locus_tag="OPY25_002681"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCS0928265.1"
                     /translation="MRTLWRFIAGFFKWTWRVLNFVREMVLNLFFIFLVLVGVGIWMQ
                     IGNGSNSEQTARGALLLDISGVIVDKPSTNHRLGALGRQLFGASSDRLQENSLFDIVN
                     AIRQAKDDRNITGIVLDLKNFTGADQPSMRYIGKALREFRDSGKPVFAVGENYSQGQY
                     YLASFANKIWLSPQGQVDLHGFATNGLYYKTLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLHTVSANRQISPQQLFPGAQAIIDGLTSVGGDTAKYA
                     LDHKLVDALASSADVEKALTKQFGWSKTENNYRAISYYDYSLKTPADTGGTIAVIFAN
                     GAIMDGEETPGNVGGDTTASQIRDARLDPKVKAIVLRVNSPGGSVNASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVASPSTLTGSIGIFGVINTVENSLSSIGV
                     HSDGVSTSPLADISMTKALSPEVQQMMQLSIEYGYKRFITLVADARKRTPEQIDKIAQ
                     GHVWTGEDAKANGLVDSLGDFDDAVAKAAELAKLKQWHLDYYQDEPTVLDMVMDSMTG
                     SVRAMLPEAIQAMLPAPLVSAANTVKAEGDKLAAFNDPQNRYAFCLTCANVR"
     gene            9321..10337
                     /gene="ansA"
                     /locus_tag="OPY25_002682"
     CDS             9321..10337
                     /gene="ansA"
                     /locus_tag="OPY25_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCS0928266.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSDKGYIPVSGRLQRQLALMPEFHRP
                     EMPDFTIHEYAPLMDSSDMTPEDWQHIAADIKAHYDEYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPVNEVTLFFNNRLFRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPYGSGELIVHPITPQPIGVVTIY
                     PGISAEVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELKEASSRGIVVVNLTQCMSG
                     RVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQGLDTQAIRSAMAQNLRGEL
                     TPDD"
     gene            10364..11020
                     /gene="pncA"
                     /locus_tag="OPY25_002683"
     CDS             10364..11020
                     /gene="pncA"
                     /locus_tag="OPY25_002683"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /protein_id="HCS0928267.1"
                     /translation="MTNRALLLVDLQNDFCAGGALAVAEGDSTIDIANALIDWCQPRQ
                     IPVLASQDWHPAQHGSFASQHQAEPYRQGKLDGLPQTLWPDHCVQHTDGAALHPLLNQ
                     HAIDACIYKGENPLIDSYSAFFDNEHRQKTTLDTWLREHDVTELIVMGLATDYCVKFT
                     VLDALELGYAVNVITDGCRGVNIHPQDSAHAFMEMAAAGATLYTLADWEETQGQAIAR
                     "
     gene            complement(11371..11649)
                     /locus_tag="OPY25_002684"
     CDS             complement(11371..11649)
                     /locus_tag="OPY25_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HCS0928268.1"
                     /translation="MNLDEIINSMTPEVYQRLSTAVELGKWPDGVALTPEQKENSLQL
                     VMLWQARHNTEAQHMTIDTHGQMVMKSKQQLKADFGITSKPIATLKMQ"
     gene            complement(11691..12104)
                     /gene="msrB"
                     /locus_tag="OPY25_002685"
     CDS             complement(11691..12104)
                     /gene="msrB"
                     /locus_tag="OPY25_002685"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCS0928269.1"
                     /translation="MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVY
                     HCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG"
     gene            12446..13441
                     /gene="gapA"
                     /locus_tag="OPY25_002686"
     CDS             12446..13441
                     /gene="gapA"
                     /locus_tag="OPY25_002686"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCS0928270.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDAEYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGIFLT
                     DETARKHITAGAKKVVLTGPSKDNTPMFVKGANFDKYEGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            13770..14654
                     /locus_tag="OPY25_002687"
                     /pseudo
     CDS             13770..14654
                     /locus_tag="OPY25_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
     gene            complement(14753..15610)
                     /locus_tag="OPY25_002688"
     CDS             complement(14753..15610)
                     /locus_tag="OPY25_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCS0928271.1"
                     /translation="MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLD
                     LGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVSKVYPWNAGGQKIVAACEESLRR
                     LKTDYLDLYLLHWAGGFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
                     QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQ
                     AHNATAAQILLTWVIAHPGVMAIPKAGSTEHVKQNAAALEITLSANELALLDNAWPAP
                     KGKTALDMV"
     gene            complement(15708..16904)
                     /locus_tag="OPY25_002689"
     CDS             complement(15708..16904)
                     /locus_tag="OPY25_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HCS0928272.1"
                     /translation="MSIVFNTVAKPSGSLCNLSCKYCFYLDKPRGQRVMSDDVLETYI
                     RRVIDDTPSSEVSFCWQGGEPTLCGLSFYQKVVCLQQRYANGKTIYNSLQTNGVLINE
                     EWAAFFVQHQFLIGISIDGPQVVHDNYRRTPSGRASFSRVVNAIRLLQANDVEFNTLT
                     VVNDASCRHGNAIYHFLTQELESKHLQFIPIVEPLAQKAQRSLTLSDNEDSPSLMPFS
                     VTPEGWGAFMCDVFDQWIRHDVGRIFVQLFDNLLGVWMGEPATLCTMQSTCGQSLLVE
                     QNGDVFSCDHFVFPAYKLGNLQQHSLEEMAASPFQQQFGAAKANLSSRCQNCTWRFAC
                     HGGCPKHRICMDGGERQNYLCKGYLEFFQHVTPYMNVMRQLLLNQRPAAHITRIVDMI
                     ADDVRQ"
     gene            complement(17194..17940)
                     /locus_tag="OPY25_002690"
     CDS             complement(17194..17940)
                     /locus_tag="OPY25_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MipA/OmpV family protein"
                     /protein_id="HCS0928273.1"
                     /translation="MTKLKLLALGVFIATSASVAHAESNLTLGAGVGVVEHPYKDYDS
                     DVYPIPVIAYESENFWFRGLGGGYYLWNDNADKLSIMAYWSPMYFKPGDSDDHQLRRL
                     DRRKSTMMAGVSYAHHTQYGFLRTSLAGDTLDNSNGIVWDLAWLYRYTNGGLTLTPGI
                     GVEWNSENQNDYYYGVSRKESSRSGLRGYNPNDSWNPYLELSANYNFAGNWSVYGTAR
                     YTRLSDEITDSPMVDKSWTGILSTGVTYRF"
     gene            18366..20300
                     /gene="yeaG"
                     /locus_tag="OPY25_002691"
     CDS             18366..20300
                     /gene="yeaG"
                     /locus_tag="OPY25_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HCS0928274.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQDFLTICRQDRSAYANAAERLLM
                     AIGEPNMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQRVPIYVLSANGERSPVNDHPLCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKHLHEFGGDITKFRVVKVWPSILEQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHHAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLPPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELAHAPCAPGTLETLSRFSTLSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHAEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            20423..21710
                     /locus_tag="OPY25_002692"
                     /pseudo
     CDS             20423..21710
                     /locus_tag="OPY25_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460250.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
     gene            complement(21860..22066)
                     /locus_tag="OPY25_002693"
     CDS             complement(21860..22066)
                     /locus_tag="OPY25_002693"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928275.1"
                     /translation="MKRFKEIAAILLFALLAVGFTSSAMASSGSGGGPWDFDIYFPGH
                     YFFCKLQPPDSLQLPPPPGEYCWH"
BASE COUNT         5388 a         5950 c         5659 g         5200 t
ORIGIN      
        1 ctgtaaatgt agattgcagc attcgtgcca gccagcgtta acattgcata aacagaagtg
       61 ataaacggta aatcaatggg ttacagcgta gcgatattca cttttactgc atgaaaagtg
      121 aatatttccg cataatcggt ggctagaaag aggaaaaagc gaaatattat tcagttgcca
      181 aatataattc tggaattgtg atcttatacg aaatttactg gaaattaccg ccccgttctg
      241 gcgcatctgc acgcaaaccg tgccattttc gcgctataga aaacaccata cgcttccatt
      301 ggccgaatct gacgatgagt ggcagtcacc cggtaaaatt tctgctacca tcccaacacg
      361 attcaccttg caaagtggca gtgactatga aatttgtctc ttttaatatc aacggcctgc
      421 gcgcccgtcc ccatcaactt gaagcgattg tcgaaaaaca ccagcccgat gtgatcggtc
      481 tacaggagac aaaagtccac gacgaaatgt tcccgctcga agaggtcgcg aagctgggct
      541 ataacgtttt ctatcatgga caaaaaggcc attacggcgt cgcgctgcta acaaaagcca
      601 cgcccatttc cgtcagacgc ggttttccgg atgatggcga agaggcgcaa cgccgcatta
      661 tcatggcgga aatcccctcg ccgctgggta atatcaccgt cattaacggc tatttcccgc
      721 agggggaaag ccgggatcat ccgttgaagt tccccgcgaa agcgcagttt tatcagaact
      781 tgcaaaacta tcttgaaacg gaactcaagt gcgataatcc ggtattaatt atgggcgaca
      841 tgaatatcag cccgaccgac ctggatattg gcatcggcga agagaaccgc aaacgctggc
      901 tgcgtaccgg taaatgctcc ttcctgccgg aggagcgtga atggatgtcg cggttactga
      961 agtggggatt agtggacacg ttccgtcagg caaatccgca aacgatggat aaattttcgt
     1021 ggtttgatta ccgttcaaaa ggtttcgtgg ataatcgcgg actgcgcatt gacctcttgc
     1081 tggcaagcgc tccgctggcg gaacgttgcg cagaaaccgg tatagactac gacattcgca
     1141 gtatggaaaa accctccgac catgcgccgg tctgggcgac gtttcgtgtt tgattccgct
     1201 atctgattaa ccgtaaggcc gggatagcgc gacgcttccc ggcaggaata acgaccttaa
     1261 cgacaatgat aaaaaaactc gatgttgttg ccgccatcat tgaacgcgac ggcaaaatac
     1321 tgctggccca gcgcccagtt catgcggatc aagccggttt atgggagttt gccggcggta
     1381 aagtcgaacc cggcgaaacc caaccgcagg cgcttatccg cgagctacgc gaagagttag
     1441 ggattgacgc cacgcccggc gtctatatcg ccagccatca acgcgacgtg tctggccgac
     1501 gaattcattt gcacgcctgg catgtgcctg cgtttaacgg tctgatacgt gcgctggaac
     1561 atcaggcctt agcctggtgt acgccggaag aggcgctgga ataccccctc gccccggcgg
     1621 atattccgct attgcaggcg tttatggctt tacgcgacgc cagactaacg gatttgtgct
     1681 gatggttttt tcgtcacgct ggcactggag cacgacgcct tccactttta ttaccgcgcc
     1741 ttcggagtaa ttctgatcct ggtaaacgca gcactgaatg cagggctggg atgactgacc
     1801 gcgcgtgctg aaaacttccg gcgggacatt cacctgaata tcaggacgac tgttttggtt
     1861 tgccagcccg accattggca ttatcgccat cacggcgacc atgaggcttc ggcgcatagg
     1921 atttccttat ttttccaagt atattctcag tataacggta agccgccgtg aaaactttaa
     1981 tcctcttttg tcatcgcttt tagttatgac cctctccccg ttatgaattt acttagcagc
     2041 gtcatttttt tcttgcttac cgtcacattg ctgatggtat agtcgaaaac tgcaaataca
     2101 tattctgata aaacgcaaat acaaccacat taatatataa gaggttttta tatctatgga
     2161 tcagacatgt tctctggaat cgttcctcaa ccatgtacaa aagcgcgacc cgcatcaaac
     2221 cgagttcgcg caagccgtcc gtgaagtcat gaccaccctg tggccgtttc ttgaacaaaa
     2281 cccccgttac cgccacatgt ctttactgga acgtttggtt gaaccagagc gcgtaatcca
     2341 gtttcgcgta gtgtggctgg acgataaaaa tcaggtgcag gtaaatcgcg cctggcgcgt
     2401 gcagttcaac tctgctatcg gcccctataa aggcggtatg cgcttccatc cttcggtaaa
     2461 cctttccatc cttaagttcc tcggctttga gcaaaccttt aaaaatgccc tcaccacgtt
     2521 gccgatgggc ggcggtaaag gcggcagcga tttcgatccg aaagggaaaa gcgaaggcga
     2581 agtgatgcgt ttctgccagg cgctgatgac tgaactgtat cgccatttag ggccggatac
     2641 cgacgtgcct gccggggata tcggcgtggg cgggcgcgaa gtgggcttta tggcgggaat
     2701 gatgcgcaag ctttccaata acagcgcctg cgtcttcacc ggcaaagggc tttccttcgg
     2761 cggcagcctg attcgtccgg aggcgacggg ctatggcctg gtctacttca ccgaagcgat
     2821 gcttaaacgt catggtctcg gttttgaagg gatgcgcgtc gccgtgtccg gctccggcaa
     2881 cgtagcgcaa tacgccattg agaaagcgat ggcctttggc gcgcgcgtgg ttaccgcgtc
     2941 ggattcgagc gggacggtgg tcgatgaaag tggcttcacg ccagagaagc tggcgcggct
     3001 gtgtgaaatt aaagccagcc gtgacggtcg cgtcgctgac tacgcccgtg agtttggctt
     3061 aacctatctg gaaggccagc agccctggag cgtaccggtg gatatcgccc tgccatgcgc
     3121 gacgcagaac gaactggacg ttgacgccgc gcgcgtactg attgccaatg gcgtgaaagc
     3181 cgtggcggaa ggggcaaata tgccaaccac gattgaagcg accgatctct tccttgaggc
     3241 gggcgtactg tttgcgccgg gtaaagccgc caacgcgggc ggcgtggcga catcggggct
     3301 ggaaatggcg cagaacgccg cgcggttgag ctggaaagcc gagaaagtgg acgcccgtct
     3361 gcatcatatt atgctggata tccaccacgc ctgtgtcaag tacggcggcg acaataagca
     3421 tactaactac gttcagggcg ccaacatcgc cggtttcgtg aaagtcgccg acgccatgct
     3481 ggcgcagggc gtcatttaat cccgtcgcca ggccagatgg ctttacgctt attcggtctg
     3541 acggcctgtc tcctcagcag gcgggctttt tttgcccgct cgcttacgcg gcgcgctctt
     3601 tttcttttct ccgccgcctg gcgcgactat ccctctgaaa cgcttcaccg gcgtgcgctt
     3661 agcctgatcg atcagctgat ataacgtgcc gaccagcggt tgcataaaat cctggtaacg
     3721 gcactgcttt tcgctgattt gcgtcaaaac agattcccag tgcgcggtca tatctggacg
     3781 ggccgccatc tccggcagcg aatgtattaa cgctttgcca gcatcggtag aatgaatgta
     3841 gcgccctttt ttggtcagaa agctacgttt gaacagcagt tcgataatcc cggcgcgcgt
     3901 ggcttccgtc cccagcccat cggtcgcgcg caggatcttt ttcagatctt tatcctgcac
     3961 gaagcgggca attccggtca tcgcggaaag caatgtcgca tcagtgaaat gacgcggcgg
     4021 ctgggtttgg cgttcgacca cttccccctt ttcacacagc aactcatcac ctttggcgac
     4081 aaccgacagc ggcgtaccgt cgttttcctc gtcgcgctct ttactgccca gtaacgtccg
     4141 ccaaccggcc tccgccagaa aacgcgcttt ggcgacaaat ttccctttgg cgatttccag
     4201 ttcaataacg catttacgaa acaccgcgtc cgggcagaac tgcatcagat actgacgcgc
     4261 aatcagggtg tacactttcg cttcgttttc cgtcagatgg acagaagaac tgcgcgccgt
     4321 cgggataatc gcgtggtgcg catccacttt tttgtcatcc cagcagcgat tgcgcgtatc
     4381 aggattaacc acaggctgcg gcagtaaatc cggggcgtgg acgctaatcg cgttcatgac
     4441 cgcctgccgt ccggcaaagt gttcttccgg cagataacgg cagtcggaac gcggataggt
     4501 aatcagtttg tgggtttcat atagcttctg acaaatatca agcacgtttt gcgcgctcag
     4561 gccaaaacgt ttagcggctt caatctgtag cgtcgagagc gaaaacggca gcggcgcgga
     4621 ttctgattcc cgtttatcat tataactggt taccagcgca ggctgaccgt tgattcggtt
     4681 caccacatgc tccgccagcg gacgatgaag caaacgcccc tcttcatcct gataaggttc
     4741 gcacgcctcg ctcggctgcc agatagcggt aaaacgctcg tcggcaggcg taacgatgtg
     4801 cgccttcact tcaaagaagt ctttggcgac gaagttctca atctcttcgt ctcgccgcac
     4861 caccagcccc agtaccggcg tctgcacgcg tcccacggat aacacgccct gatagccggc
     4921 attacggccc aggatcgtgt aagcacgggt catattaatg ccatacagcc agtccgctcg
     4981 cgctcgcgcc agcgcggaga cgcacagcgg cacgaagtcg ctgttcgccc gcagcctgtc
     5041 gatagcacgc tcgaccgcct gcgggttaag gtcgtttatc agacaacgcc gtacctgctg
     5101 gcgcttttcg gcaggaagct ggagataatc cagcacttca tcaaccagaa gctgcccttc
     5161 gcgatccggg tcgccggcgt gaataatttc accggcttga tgcaaaaagc gcttaatcac
     5221 attgagctgt ttggtgacgg aaggacgagg ctgaagctgc catttttccg gcacgatagg
     5281 caggtcagcc agattccagc gcgcataacg gctgtcatac gcatccggct gcgcctgttc
     5341 cagcaaatga ccaatacacc aggtgacgac ctgcccgttt ccgcactcaa taaaaccatc
     5401 gcctttacgg tgcggttttg gcagcacatc cgcaatggcg cgccccagac tcggtttttc
     5461 ggcaataaac aaccgcatca ggttaacgaa tctcaaccat agcgcgaccg ccgcgggcct
     5521 cgaccagttc gccaatcgcg gtcagttcga taccaaattc cgccgcggtg gctttaacat
     5581 cgtcttcggc gtccggcgtt accgccaaca gcagaccgcc tgacgtttgc ggatcgcaca
     5641 gcaggctacg aacttcacgc gacatgtcgc ccatcagatg accatagctg gcgaagttgc
     5701 gctctgtgcc gcccggtacg gcgcccagag caatatactc ttccacgccc ggcagtttag
     5761 ggatgtcctg atagcaaagc atcgcctgta cgcctgcacc ctggcacatc tcgctcaggt
     5821 gtcccagcag accaaaaccg gtaacgtcag tcatggcttt tacgccgtcg atattggcaa
     5881 acgccgcgcc agcaacgttc atccgacaca tgacttccgt cgccagcccc tgatgttcag
     5941 gtttaagcag cgattttttc tcggcggtgg tcaacacgcc aatccccaac ggtttggtca
     6001 gaaagagttt gcatcccgcc tgcgcggtac tgtttttctt cacccgttcg gtcggcacta
     6061 cgcctgtgac cgcgagacca aagatcggct ccggggcgtc aatagagtgt ccgcccgcca
     6121 gcgcgatacc ggcctgacgg caggcaaaac gccccccctc ggtcacttca cgcgcaatat
     6181 cgggcgacag ggtattaatc ggccagccaa ggatcgcgat cgccataatc ggtttgccgc
     6241 ccatcgcaaa aatatcgctg atggcgtttg ttgccgcaat gcggccaaaa tcaaacgggt
     6301 tgtcgactat cggcataaag aagtcagtgg tgctgataat actggtgcca ttacccagat
     6361 cgtaaactgc cgcatcatcg cgggtttcat tacccaccag cagattcggg tcgacgaact
     6421 tcgcctgctc gctatgcagg atagtctcca gcactttagg ggaaatttta caaccgcaac
     6481 cagcgccgtg gctgtattgc gttaaacgaa tggcttgctt gctcatggac atctcctgtc
     6541 attgcattcg cgctatggta gcgctcattc cctgatgtgg taagtatcac tgtctgaatt
     6601 accgcgcctt tgctcagaat ccagacagtt ttatccctca gcgtcagaaa taacgcacaa
     6661 acggcgtggg gtcgggggta ctgatcgtcg ttgacgcttt gagctgcggc gtgccgagat
     6721 agagaaaacc aacaatttta tcctgaggac ggcactcaaa ggcttcccgc acgatagcgc
     6781 tctccgttaa tgcgccgcta cgccagatac cattaaaccc ttgcgcaatc gctgccattt
     6841 gcatcgccat caccgcgcat ccggcagaca tctcctgttc ccacacggga accttatggt
     6901 tttcttcgca tttcgccacc acggtaatga tcagcggcgc gcgaaacggc gcattacgcg
     6961 ctttttcgat cgctttctca tcccccccgg cagcgacagc gccttgttca agcacggcgc
     7021 tgaagcggtc gcgcccctct ccttcaatca caaaaaaacg ccacggctgt agagatttat
     7081 gatcgggaac acgcattccc gcccgcagaa tgttctgtaa ttgctctccg acaggcgccg
     7141 gttctgcgag acgagaggcg ctgcgacggt tgaccagcag ttctagtgca tccatttgat
     7201 taactccagc aatgatattt attcacaaaa ttaacacggg agcggatttt gttacagcgc
     7261 aggcagtgat tcctgctgac aactgcctga tgggtcatta cgatagccac atcttaatgc
     7321 tttatcctca ccaaggtata agcgttgtta ctcagatagg gagaatacat gcgaaccctg
     7381 tggcgattta ttgccggatt ttttaaatgg acgtggcgag tgttgaactt cgtccgtgaa
     7441 atggtactca acctgttctt tatttttctg gtcctggtgg gcgttgggat ctggatgcag
     7501 atcggtaacg gcagcaacag tgagcaaacg gcgcgcggcg ctttgctgct ggatatttcc
     7561 ggcgtcattg tggataaacc ctccaccaat caccgtctgg gcgcgctggg acgccagtta
     7621 tttggcgcca gctccgaccg tctgcaggaa aactccctgt ttgacatcgt caacgctatt
     7681 cgtcaggcga aagatgaccg taacatcacg ggtatcgttc tggatctgaa aaacttcacc
     7741 ggtgccgatc agccgtcaat gcgctatatc ggtaaagcgc tgcgcgaatt ccgcgatagc
     7801 ggcaaaccgg ttttcgccgt gggtgaaaac tacagccagg gtcagtatta cctcgccagt
     7861 ttcgccaata aaatttggct ttccccacag ggtcaggtag atcttcacgg cttcgctacg
     7921 aatggcctgt actacaaaac gctgctggat aaactgaaag tctctaccca cgttttccgg
     7981 gtcggcacct ataaatccgc cgtcgagccg tttatccgcg acgatatgtc gcccgccgcc
     8041 cgcgaggccg acagccgctg gataggcgaa ctgtggcaga actacctgca taccgtttcc
     8101 gccaatcgcc agatttcgcc gcaacaactc ttccccggcg cccaggctat tatcgacggg
     8161 ttaaccagcg tgggcggtga caccgccaaa tatgcgctcg accataaact ggtggacgcc
     8221 ctcgcctcca gcgcagatgt tgaaaaagcg ctgacgaagc agtttggctg gagcaaaacc
     8281 gaaaataact atcgcgcgat cagctattac gattattcgc tgaaaacgcc tgcggatacc
     8341 ggcggtacta ttgcggttat tttcgccaat ggcgcgatta tggatggcga agaaacgcca
     8401 gggaatgtcg gcggcgacac tacggcatcg cagatccgcg acgcacgcct tgatcctaaa
     8461 gtgaaagcga ttgtgctgcg cgtcaatagc ccaggcggta gcgtcaacgc ctccgaagtt
     8521 atccgcgccg aactggcggc ggcaagagcg gctggcaaac cggtggtggt ctcaatgggc
     8581 ggcatggcgg cctccggcgg ttactggatc tctacgccgg caaactatat cgtggccagc
     8641 cccagcacgc tgacgggttc aattggcatc ttcggcgtaa ttaatacggt agaaaacagc
     8701 ctgtcgtcga ttggcgtaca cagcgacggc gtttccacct cgccgctggc ggatatttcg
     8761 atgactaaag cgctgtcacc ggaagtgcag cagatgatgc aactcagtat tgagtacggc
     8821 tacaaacgct ttatcacgct ggtggcagac gcgcgtaagc gtacgccgga gcagattgac
     8881 aaaatcgctc aaggccatgt ctggaccgga gaagacgcga aagccaatgg tctggtggac
     8941 agtctcggcg actttgacga cgccgtcgcc aaagcggcgg agctggcgaa actgaaacag
     9001 tggcatcttg attactatca ggacgaaccg acagtccttg atatggtcat ggacagtatg
     9061 accggatctg tacgcgccat gctgccggag gccattcagg cgatgctccc ggcgccgctc
     9121 gtttccgccg ccaacacggt gaaggccgag ggggataaac tggcggcatt taacgatcca
     9181 caaaaccgtt atgcgttctg tttgacttgc gcgaacgtgc gctaatgctt catcaatagc
     9241 cataccggat gtcggcgtct gctcatagcc gccatccgat aatcattaat acgtccttcg
     9301 cgacacgact gaacattatc atgcaaaaga aatcaattta cgttgcctat accggcggta
     9361 ctatcggtat gcagcgctcc gataaagggt atatcccggt gtccgggcgc cttcagcgtc
     9421 agctggcgct gatgccggaa ttccaccgcc cggagatgcc ggattttacc atccatgaat
     9481 atgccccgct gatggattca tcagatatga cgccggaaga ctggcagcat atcgctgcag
     9541 atatcaaagc gcactacgat gagtatgacg gttttgttat tctgcacggc accgacacga
     9601 tggcgtatac cgcatcggcg ctctctttca tgctggaaaa tctgggtaaa ccggttattg
     9661 tgacagggtc acaaattccg ctggctgagc tgcgctccga cgggcaaatt aatttgctga
     9721 atgcgcttta tgtcgccgcc aactaccctg ttaatgaagt aacgctgttt tttaataatc
     9781 gtctgttccg cggcaatcgc acgaccaaag cacatgcgga tggttttgac gcttttgcct
     9841 ctcctaatct gccgcccttg ctggaagcag gaattcacat tcgccgttta aatacgcctc
     9901 ccgcgcccta cggttctggt gaattaatcg ttcaccctat tacgccgcag ccgataggcg
     9961 tagtgacgat ttatccgggg atttccgccg aggtagtacg taactttctg cgtcagccgg
    10021 taaaagcgct gattctgcgc tcttatggcg taggcaacgc gccgcaaaat aaagcgtttt
    10081 tacaggagct gaaagaggcc agttcgcgcg gcatcgtggt ggttaacctg acgcaatgca
    10141 tgtcagggcg agtcaatatg ggcgggtacg ctaccggtaa tgcgctggcg cacgctggcg
    10201 tgattggcgg tgccgatatg accgtcgaag ctaccttaac caaactgcat tatttgttaa
    10261 gccagggtct ggacactcag gcgattcgta gcgcgatggc gcaaaacttg cgtggtgaat
    10321 tgacgccgga tgattaaaaa atcccgacga caaggagaag ataatgacaa accgggcctt
    10381 attactggtc gacttgcaaa atgacttttg tgccggcggc gcgctggctg tagcggaagg
    10441 cgacagcacc atcgacatcg ccaacgctct tattgactgg tgccagcccc ggcagattcc
    10501 ggtgctggcc agccaggact ggcatcccgc gcagcatggc agcttcgcca gccagcatca
    10561 ggcggaaccc tatagacagg gaaagctgga cgggctgccg caaacgctct ggccggatca
    10621 ctgcgttcaa cataccgacg gcgcggcgtt acatcccctg cttaaccaac atgcgattga
    10681 cgcctgcatc tataaaggtg aaaacccgct gattgatagc tacagcgcgt tttttgacaa
    10741 cgaacatcgg cagaaaacta cccttgatac ctggcttcgc gagcatgacg ttaccgagct
    10801 tatcgtgatg gggttggcga ccgattactg cgtaaaattt acggtgctgg atgcgctaga
    10861 gttgggctat gccgttaacg ttatcaccga tggctgtcgc ggcgtgaata ttcacccgca
    10921 ggatagcgca cacgcgttta tggagatggc ggcggcaggc gcgacgctgt atacgctggc
    10981 agactgggaa gagacgcagg gccaggctat cgccaggtag cggagcaggt atcgtatccg
    11041 gtcaatacat cacgcaacgg tgagaccatt gcatagatct ttgggccgga tacgtcacgt
    11101 cagcgtcgct accaggcaaa gctcaacgca ggctggagag cgcttctaac gaaacagatt
    11161 aaaaagcgcg ggctggccgg cgcaatgttc tgggaatagg ccgccaatga caataatcag
    11221 ttagcgaaac agttggcgga ctcgctggac attaagcgta atgggtaaaa atatggcggg
    11281 cctgtgcctg acagcaatga gcaggcccgg taagcacaac gcattggcaa ttaaaccacc
    11341 ggatggcgac tacctcttat ccggctgccg ttactgcatt ttcaatgtcg caatcggctt
    11401 tgacgtaata ccgaaatccg ctttgagctg ctgcttgctt ttcatcacca tctgaccgtg
    11461 agtatcgatc gtcatatgtt gcgcttcggt attgtgccgc gcctgccata gcatcaccag
    11521 ttgcaggctg ttttctttct gttccggcgt caacgccacg ccatccggcc atttacccag
    11581 ctcaacggcg gtggataaac gttgatacac ttccggcgtc atgctgttaa tgatctcatc
    11641 aagattcatg atgtgtccgc tcctgtggaa taatttgctg aatcgttttt tcagcctttc
    11701 agttgatcgc cgtttttctc gtcagaaaag gccagcgagg ccgagttaac gcaatagcgc
    11761 tcaccggttg gctgcggccc gtccgggaaa acgtgtccga gatgcgcatc gcagttaccg
    11821 caacgaattt cgacacgctg catgccatga gaaaaatcgt ctatgtaacg aatcgcctct
    11881 tcgctgacag gctggtaaaa gctaggccag ccgcagcctg aatcgtattt ggtgtgggag
    11941 tgaaaaagcg gcgtatcaca gaccaggcag tgataaaccc catcgcgttt attatgtagc
    12001 aggcgtccgg taaatggcgg ttctgtgcca cgatcctgcg tcacatagaa ttgcatttcg
    12061 gacaattttt tcttgagttc ttctgctgaa ggttggttag ccatttgctc acatctcact
    12121 ttaaacgtgc tcacattgcc tgaccgattc taacaaaaca ttagcacctc agtaccaact
    12181 tttgttctaa acttgatcat tgcgaaatgg cggctcacga atcgtgactg atgtcacatt
    12241 attatctcgg ttgcccttta aaattcgggg cggcgccccc atgtggtttc aagctgaaag
    12301 gaagagtgag gcgaatcagc cgcgcaaagg ttgtgcagag gattgatttg tcgcaatgat
    12361 tgacacgatt ccgcttgacg ctgcgtaagg tttttgtaat tttacaggca accttttatt
    12421 cactaacaaa tagctggtgg aatatatgac tatcaaagta ggtatcaacg gttttggccg
    12481 tatcggtcgc attgttttcc gtgctgctca gaaacgttct gacatcgaga tcgttgcaat
    12541 caacgacctg ttagacgcag agtacatggc atacatgctg aaatatgact ccactcacgg
    12601 ccgtttcgac ggtactgttg aagtgaaaga cggtcatctg atcgttaacg gtaaaaaaat
    12661 ccgtgttacc gctgaacgcg atccggctaa cctgaaatgg gacgaagttg gtgttgacgt
    12721 agtggctgaa gctaccggta tcttcctgac tgacgaaacc gcgcgtaaac acatcaccgc
    12781 tggcgcgaaa aaagtggttc tgacgggtcc gtctaaagac aacaccccaa tgtttgttaa
    12841 aggcgctaac tttgacaaat acgaaggcca ggacatcgtt tccaacgctt cctgcaccac
    12901 aaactgcctg gcgccgctgg ctaaagttat caacgacaac ttcggcatca tcgaaggtct
    12961 gatgactact gttcacgcga ctaccgcaac ccagaaaacc gttgacggcc cgtctcacaa
    13021 agactggcgc ggcggccgcg gcgcatctca gaacatcatc ccgtcctcta ctggcgctgc
    13081 taaagcggta ggtaaagtac tgccggaact gaatggcaaa ctgactggta tggcgttccg
    13141 cgttccgact ccgaacgtat ccgttgttga cctgaccgtt cgtctggaaa aagcggctac
    13201 ctacgagcag atcaaagctg ctgttaaagc tgctgccgaa ggcgaaatga aaggcgttct
    13261 gggttacacc gaagacgacg ttgtatctac cgatttcaac ggcgaagtat gcacttccgt
    13321 gttcgatgct aaagcaggca tcgcgctgaa cgacaacttc gtgaaactgg tctcctggta
    13381 cgataacgaa accggttact ccaacaaagt actggacctg attgctcaca tctccaaata
    13441 agttgagatg acacagtcat tggtaagagc gactcaggtc gctctttttt ttgcttaaag
    13501 atatacccgt catacttcaa gttgcaggtg tgttggctat gctttctcac ccgaatcact
    13561 gacggaagtc gaacttatcg ggatgaatca gggatgcccc tgaccgaagg ttacctacgg
    13621 ttgttcaaat tcgttcccga tgaatttgtc gttcacttgc cgcgttactc ggcctgcggc
    13681 ctcgcctcta cgggccagcg caagcactgg tcaaggcaca agcgccttgt catgcaactc
    13741 gaattattta gggttaagag gattgcgtaa tgattaataa aatttttgcc ctcccggtta
    13801 tcgaacagct tacccctgtc ctttcccgtc gtcagcttga tgacctggat ctgatcgtcg
    13861 ttgaccatcc gcaggttaaa gcctcttttg cattacaggg cgcgcacctt ctctcctaga
    13921 aacccattgg cgaggaagag gtattgtggc tcagtaataa tacgcctttc aaaaccggcg
    13981 tggcgctacg cggcggcgta ccgatctgct ggccctggtt tggacctgcg gctcaacagg
    14041 gtctgccgtc acacggcttt gcgcgtaatc ttccgtgggc gctaaaagcg cataatgaag
    14101 atgataatgg cgtaatgctg acatttgagc tgcaaagcag tgaggccacc cggaaatact
    14161 ggccgcacga tttcacgctg ctggcacgtt ttaaagtggg taaaacctgt gaaattgaac
    14221 tggaagcgca tggcgaattt gcaaccacat ccgcgctcca cagctatttt aacgttggcg
    14281 acatcgccaa cgttaaggtc agcggactcg gcgatcggtt tattgataaa gttaacgacg
    14341 ctaaagaaga tgtcctagcc gacggtatac aaacctttcc ggaccgtacc gatcgcgttt
    14401 acctcaatcc tgaagcatgt agcgtgatcc acgatgcgac attaaaccgc acgattgatg
    14461 tggtccacca ccatcacctt aacgtcgtag gctggaaccc tggcccggcg ttgtccgtca
    14521 gcatgggcga catgccggat gacggctata aaacgtttgt ctgcgttgaa acggtttacg
    14581 ctactgcgcc gcaacaagcc acagaagaaa aaccctctcg tctggcgcag actatctgcg
    14641 tcgctaaacg ctaaaagtga atggataacg gcgttgctat aggctctgga aggcgccagc
    14701 cgccatcagg catgacctgc cggatggcgg cacttacaca ttttatccgg cgtcacacca
    14761 tatccaacgc ggttttccct tttggcgcag gccaggcgtt gtccagtaag gcaagttcgt
    14821 ttgctgacaa ggtaatctca agcgccgccg cattttgctt cacgtgttct gtacttccgg
    14881 ctttcgggat cgccatcacg cccggatgcg caatcaccca cgtcagtaag atttgcgccg
    14941 ccgttgcgtt atgcgcttgc gcaatttcat tcaccaccgg atgattcagt aaaccgctac
    15001 gtaaccggcc agcctgcgcc agcgggctat aggccatcac tggcattcgc tgttgttgac
    15061 accacggcaa taaatcatac tcaataccgc gtgacgccag atgatagagc acctgatttg
    15121 tcgcgcattg ctgtccccca gggatgcgcc acagcgcctg catatcgtca taatcaagat
    15181 tagagactcc ccaacggcga atttttccct gcgcgattag ccgctccata ccttcaacgg
    15241 tctcttcgaa tgaaaagcct ccggcccagt gcaatagata gagatcgaga taatctgttt
    15301 tcagacgacg caggctttcc tcacaggcgg caactatctt ctggccgcca gcgttccacg
    15361 ggtacacttt tgacactaga aatgcctcat cgcgtcgccc tgctaacgcc tcgcccacga
    15421 ccttttccgc cccgccgtcg gcatacattt ccgccgtatc aataaggcgt aaccccaaat
    15481 ccagccccgc gcgcagcgcc gaaacctcgc gctgacgttg atccgcgcgc tcgcccatat
    15541 accatgttcc ctgtccgatg gcaggaagcg tcacctgccc gcaaaacgtt acgtttttca
    15601 ctgatttcat ttccttttca atttcactcg acggtaaaac aatacaggac tcttagaccc
    15661 tacggtaatg tccggcatca taccgcgcaa ggggggcgat tttcttgtca ctgacgaacg
    15721 tcatccgcaa tcatgtcgac gatgcgggta atatgcgcgg cgggtcgctg attcagtaat
    15781 aattgacgca tcacattcat atagggcgtc acatgttgaa agaactccag atatccttta
    15841 cagagataat tttgccgttc gccgccgtcc atacaaattc gatgtttcgg acaaccgccg
    15901 tgacaggcaa agcgccacgt acagttctgg cagcgtgaag aaaggtttgc tttagccgcg
    15961 ccaaactgct gctgaaaagg agaggccgcc atttcttcta aagagtgttg ctgcagattg
    16021 cccagtttat aggcgggaaa aacaaaatgg tcacagctaa acacgtcgcc attctgctcc
    16081 accagcaaac tttgcccgca ggtcgactgc atcgtacaaa gcgtggcggg ctcccccatc
    16141 cagacgccaa gtaagttatc aaaaagctgt acgaatatgc gtccgacatc gtgacgtatc
    16201 cattgatcaa aaacatcgca cataaaggcc ccccaccctt caggcgtgac ggaaaagggc
    16261 atcagcgaag gcgaatcttc attgtcagat aacgtcaaag aacgctgcgc tttttgcgcg
    16321 agcggctcaa caatgggaat aaattgtagg tgtttacttt ccagttcctg cgtcaaaaaa
    16381 tgataaatag cgttgccatg acggcatgat gcatcattca cgacagtgag cgtattgaac
    16441 tcgacatcat ttgcctgcag aaggcggata gcattaacga ctcgggaaaa agacgcccgc
    16501 cctgacggcg ttctccggta attatcatga acgacttgcg gcccatcaat cgatatacca
    16561 atcaggaact ggtgctgcac aaagaaagcc gcccactctt cattgattaa tacgccattg
    16621 gtttgcagac tgttgtaaat agttttgccg ttggcatagc gttgctgcaa gcacaccact
    16681 ttttgataaa aagaaagacc gcatagcgtc ggctctcccc cctgccaaca aaacgagacc
    16741 tctgatgatg gcgtatcatc aattacccgg cggatatacg tctccagcac atcgtcagac
    16801 atgacgcgct ggccccgggg tttatcaaga tagaaacagt acttgcagga taagttacac
    16861 agactgccgc tgggcttggc cacggtattg aatactatgc tcattcgtct tactcgctgt
    16921 gaagaatggg tatagcataa gcgggacgtg acagggcgat atcagccagc attgcaacaa
    16981 ttattacgct aattgttagc gcagttgtaa tcacctggat ttttcatata aaaggctagt
    17041 tttttaaatt gatgtaacaa agtataaatc acgtaaggct gcgccatacc cggtcaacag
    17101 cgcatttatg caagccgcca tgttcgcgtt tcagacagca caaagcccgc ataacgcagg
    17161 ctttgtcatg gtttttccgg caaattcaat caatcagaat ctataggtca cgccagtaga
    17221 aaggataccg gtccaggatt tatccaccat cgggctgtcg gtaatttcat ccgacaggcg
    17281 ggtgtagcgc gcagtaccat atacgctcca gttaccggcg aaattatagt tagcgctcag
    17341 ttcaagatac gggttccagc tatcgttcgg gttatagccg cgcaggccgc tacgcgaaga
    17401 ttctttacgt gatacgccgt aatagtaatc gttctggttc tcgctattcc attcaacccc
    17461 gatacctggc gttaaggtca gcccgccatt ggtataccga tacagccagg ccagatccca
    17521 gacaataccg ttactgttat ctaacgtatc ccctgccagt gaggtacgca ggaatccata
    17581 ctgggtgtgg tgcgcgtaag aaacgcccgc catcatagta cttttacgcc tgtccagacg
    17641 acgcaactga tggtcatcgc tgtcgcccgg tttgaagtac atcggggacc agtatgccat
    17701 gattgacaac ttatcggcat tgtcattcca caagtagtac ccgccgccca gaccacggaa
    17761 ccagaagttt tcgctttcat aagcgatgac cggtatcgga taaacatcgc tatcgtaatc
    17821 tttataaggg tgttcaacca caccaacgcc tgcgcccaac gtcaggttgc tttcagcgtg
    17881 cgcgacgctg gcggatgttg caataaacac gccaagagcc agaagtttaa gtttggtcac
    17941 aatccataat tccttattca aatgttctgc ggcaaaagtg taaccgccaa tacctgtaag
    18001 cccaactatt ttacacaatg taaccgttta atatcaccat caccgattat tttcagatga
    18061 tcggctgatg atcgttatgt ggccgggaac gctttttctg atatccacca gccttttcta
    18121 cctgatgagt tattgatatg tcatcgaaat tcactgacgc gtacaggcaa gttttgcaaa
    18181 tgccatctac gcttaatgtt aagaaggtgt atcaccggac acgttgatct tctgaccaat
    18241 aaaatggcat gagagttgct ttttttcctt agcagagacg gcgttcagtc tacctcttcc
    18301 gggagcctct actattcata tgaacggctc ttaacatgtg cgaaaaaacg aaagaatggc
    18361 atatcatgaa tatattcgat cactatcgcc agcgttacga agctgccaag gacgaagagt
    18421 tcacactgca ggattttctt accatttgtc ggcaagatcg cagtgcttat gccaacgcgg
    18481 cagagcggct attaatggct atcggcgagc ctaatatggt cgacactgcc caggaacccc
    18541 gactttcccg actcttctcc aaccgggtta ttgctcgcta tcctgcgttt gaagagtttt
    18601 acggcatgga agacgcgatt gaacagattg tctcttatct gaaacatgcg gcgcaagggc
    18661 tggaagagaa gaagcaaatt ctctatttgc tgggacctgt ggggggtggc aaatcatcgc
    18721 tcgctgaacg gctgaaatcg ctaatgcagc gcgtgccaat ttatgtttta agcgccaacg
    18781 gcgagcgtag tccggtcaac gatcatccgt tatgcctgtt taatccgcag gaagacgcgc
    18841 agattctgga aaaagagtac ggtattccgc gccgctatct cggtacgatt atgtccccgt
    18901 gggcggccaa acacctgcat gagtttggcg gcgatattac taaattccgc gtggtgaaag
    18961 tctggccctc cattctggag cagattgcca tcgccaaaac ggaacccggc gatgaaaaca
    19021 accaggatat ttcggcgctg gtcggcaagg tggatattcg taaactcgaa catcacgccc
    19081 agaacgatcc ggatgcgtat ggttactctg gcgcgctatg ccgcgctaac caggggatca
    19141 tggagttcgt cgagatgttt aaagcgccta ttaaggtgct gccccccttg ctgaccgcaa
    19201 ctcaggaagg taactacaat ggtacggaag gtatttccgc cctgcccttt aatggcatca
    19261 tacttgccca ctcaaacgaa tctgaatggg tgactttccg taacaataaa aataacgaag
    19321 cgttcctcga ccgtgtctat attgtgaagg tgccttattg cctgcgaatc tccgaagaga
    19381 tcaaaatcta cgagaaacta cttaatcata gcgagctggc tcatgcgccc tgcgcgccgg
    19441 gcacattgga aacgctttcg cgcttctcga ctctttcccg cctgaaagag ccggaaaatt
    19501 ccagtattta ctcgaaaatg cgcgtttatg acggtgaaag cctgaaagat accgacccca
    19561 aagctaaatc gtaccaggag tatcgcgact atgcgggtgt ggacgaaggg atgaacggtc
    19621 tctccacccg attcgccttt aagatcctct cccgcgtatt caacttcgac catgcggaag
    19681 tggcggcaaa cccggtacat ctgttctacg ttctggaaca acaaatcgag cgcgagcagt
    19741 tcccgcagga gcaagctgag cgttatctgg agttcctgaa aggctacctg atcccgaaat
    19801 acgccgaatt tatcggcaag gagatccaga cggcctatct cgaatcttac tctgagtacg
    19861 ggcagaacat ttttgatcgt tacgtgactt atgcggattt ctggattcag gatcaggagt
    19921 atcgcgaccc agataccggt caactgttcg atcgcgagtc gctgaacgcc gaactggaaa
    19981 aaattgaaaa accagcgggt atcagtaacc cgaaagattt ccgtaatgag atagtaaact
    20041 ttgtcctgcg cgccagagcc aacaatagcg gccgtaatcc aaactggacc agttacgaga
    20101 agctgcgcac ggtgattgag aaaaaaatgt tctctaatac tgaagagctg ttgccggtca
    20161 tttcttttaa cgccaaaacg tcgactgacg agcagaaaaa gcatgacgac tttgtcgatc
    20221 ggatgatgga aaaagggtat acccgtaagc aggttcgttt gctgtgcgag tggtacctgc
    20281 gcgtgcgtaa atcgtcgtga tgttaatgcc cggtggcgct tgcgcttacc gggcctacaa
    20341 agtaatgttc tgtagactgg ctaagcgtta gcgctatccg gcactaacag aacaggcgct
    20401 cagttggcag tacggggggc atatgacctg gttcatagac cgacgtctta acggcaaaaa
    20461 taaaagcacg gtgaatcgcc agcgcttttt gcgtcgttat aaagcacaaa ttaagcagtc
    20521 gatttccgaa gcgattaata aacgctcagt gaccgatgtc gacagcggag agtccgtctc
    20581 tattccaacc gatgatatta gcgaaccgat gtttcatcag gggcgcggcg gtctgcgcca
    20641 tcgcgtccat ccgggtaacg atcactttat ccagaatgat cgcattgagc gtccgcaaag
    20701 cggtggcggc ggcggttccg gcagcggtca aggtcaggcc agccaggacg gcgaaggcca
    20761 ggatgagttt gtttttcaga tttcaaaaga tgagtatctg gatctgctct ttgaagattt
    20821 agcgctgcct aatctgaaaa aaaaaccagc atcgccagct taacgagtat aaaactcacc
    20881 gcgccggttt cacctcaaac ggcgtgccgg ccaatatcag cgtggtacgt tcgctacaaa
    20941 actctctggc gcgccgtaca gcaatgacgg caggaaaacg ccgcgaactg cacgcgctgg
    21001 aaacggaact ggagaccatc agccacagcg aaccagcgca actgcttgaa gaggagcggt
    21061 tacgtcggga gattgccgaa ctacgggcta aaatcgagcg agtgccgttt atcgacactt
    21121 ttgatttacg ctataaaaat tatgaaaaac gacctgagcc ctccagccag gcggtgatgt
    21181 tctgtctgat ggacgtctcg ggttcgatgg accaggcaac caaagatatg gccaagcgtt
    21241 tttacattct gctttatctg tttttgagcc gaacgtataa gaacgtagaa gtggtttata
    21301 tccgccacca tacccaggcg aaggaagtgg atgaacatga gttcttttat tcgcaagaga
    21361 ccggggggac gattgtctcc agcgcgctta aactcatgga cgaagtagtt aaagagcgct
    21421 acgaccccag tcagtggaac atctatgcgg cgcaagcgtc agacggtgat aactgggccg
    21481 acgattcacc gctgtgtcat gagattctgg cgaaaaagct gctgccggta gtgcgctatt
    21541 acagctatat cgagattacc cgccgcgccc accagacctt atggcgcgag tatgaacatc
    21601 tgcaggcgac gttcgataac ttcgccatgc agcatattcg cgatcaggag gatatttatc
    21661 cggtattccg cgaattgttt cagaaacaga gcgccaatca aagtgcataa ccctaaatca
    21721 gcccgtaatg cgtcacgggc tgatttatca ctaacaaggc gattatacat attgccacta
    21781 caatagccgt aaacctgtat atctcctgac tggatttacc ttacatgcgc cgacttatca
    21841 ctggaatagt atggatttat taatgccagc aatactcacc aggaggtggc ggtaattgca
    21901 gagaatcagg gggttgtagt ttgcaaaaaa agtagtgacc aggaaaatag atatcaaaat
    21961 cccacgggcc accaccactg cccgacgatg ccatagccga cgacgtgaac cccacggcca
    22021 gcaatgcaaa aagcaaaatt gctgctattt ctttaaatcg tttcatagta cctccgaacg
    22081 gaagtacatt attatcctta ccacgtcaca ctcctttcac gtaataataa aggctatttt
    22141 attttcgtta gtgttaaatc gatgccgtta attaacaatt tactttttgc gacaata
//
LOCUS       DAJVKX010000069        22143 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000069 DAJVKX010000000
VERSION     DAJVKX010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22143
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.069"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            231..1277
                     /gene="ansB"
                     /locus_tag="OPY25_002694"
     CDS             231..1277
                     /gene="ansB"
                     /locus_tag="OPY25_002694"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HCS0928276.1"
                     /translation="MEFFRKTALAALVMGFSGAAFALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVDAVPQLKDIAVVKGEQVVNIGSQDMNDEVWLTLAKKINTECDST
                     DGFVITHGTDTMEETAYFLDLTVKCNKPVVLVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KQSANRGVLVVMNDTVMDGRDVTKTNTTDVATFKAVNYGPLGYIHNGKIDYQRTPERK
                     HTTSTPFDVSKLTALPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKTVF
                     DTLATAAHNGTVVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPKQIQTMFNQY"
     gene            1410..2417
                     /locus_tag="OPY25_002695"
     CDS             1410..2417
                     /locus_tag="OPY25_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 domain-containing protein"
                     /protein_id="HCS0928277.1"
                     /translation="MVRQWIAGAALFALISGYSWAEVAQPSDNILKEQFSKQYHGILK
                     LDSITLKNLDSTGNQATWSAEGDISSREDMYTGVGMAADYYFVEKTWTKDRPVKFSAM
                     LTSKGTPASGWTVSYYSLQMAASDQGRAIDDIKTNDKYLIVNSDDFNYRFGNIEASWR
                     AQKASIPGLEEQLSALDKKIAVAKKEADAYWGKGADGKPLTRAEAFKKTLKERDDYVK
                     ANDSSVYAEKYEKEVYQPALDACRKQSEPCNEAAIQQKRDLDIHEQRRQVFLKSEELR
                     RKAQNDWITLEKGQYPLNIAVQKLQMQQSDIRMKIMDINDGYERWKKDTDDLRRKGVI
                     K"
     gene            complement(2508..3644)
                     /gene="hemW"
                     /locus_tag="OPY25_002696"
     CDS             complement(2508..3644)
                     /gene="hemW"
                     /locus_tag="OPY25_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HCS0928278.1"
                     /translation="MAKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     SDLDADVAWAQGREVKTIFIGGGTPSLLSGPAMQTLLDGVRARLNLAADAEITMEANP
                     GTVEADRFIDYQRAGVNRISIGVQSFSEPKLKRLGRIHGPQEAMRAARLANGLGLRSF
                     NLDLMHGLPDQTLEEALNDLRQAIALNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGYMQGRYLESQRDVSDDDKPFEFFMNRFRLLERAPRAEFVDYTGLT
                     EAVIRQPIDEAIAQGYLTECEQYWQITRHGKLFLNSLLELFLAE"
     gene            complement(3637..4230)
                     /locus_tag="OPY25_002697"
     CDS             complement(3637..4230)
                     /locus_tag="OPY25_002697"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HCS0928279.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDVVAQTKLGVDSAEETGL
                     TFIENAILKARHAAKMTGLPAIADDSGLAVDVLGGAPGIYSARYSGENATDQQNLEKL
                     LHTLRDVPDDKRQARFHCVLVYLRHAEDPTPIVCHGSWPGVITRQAAGNGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            complement(4238..4528)
                     /locus_tag="OPY25_002698"
     CDS             complement(4238..4528)
                     /locus_tag="OPY25_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HCS0928280.1"
                     /translation="MSAVTRCEDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLTKFLGKQFRVAKSQIVIEKGELGRHKQVKIIHPQQIPPEIAALTE"
     gene            complement(4525..5091)
                     /locus_tag="OPY25_002699"
     CDS             complement(4525..5091)
                     /locus_tag="OPY25_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCS0928281.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRVWMQWARCDFYNPFSQFVVKIT
                     QPIIGPLRRIIPPMGPIDSASLLVAFILSVIKAIVLFKVITFQAIIWIAAVLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLAEPLLSPIRRILPAMGGIDFSPMVLVL
                     LLYVVNMGIAEVLQATGNMLLPGLWMAL"
     gene            complement(5110..5814)
                     /locus_tag="OPY25_002700"
     CDS             complement(5110..5814)
                     /locus_tag="OPY25_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCS0928282.1"
                     /translation="MNDIAHNLAHIRDKISAAATRCGRSSEEVTLLAVSKTKPASDIA
                     EAIAAGQRAFGENYVQEGVEKIRHFQEAKVEGLHWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIASRLSEQRPDNLPALNVLIQINISDENSKSGIPLAELDELAAAVATLPRLRL
                     RGLMAIPAPESDYVRQFEVARQMAVAFAGLKARYPDVDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYTKN"
     gene            5832..6812
                     /locus_tag="OPY25_002701"
     CDS             5832..6812
                     /locus_tag="OPY25_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HCS0928283.1"
                     /translation="MNMEEIVTLSVKHNVSDLHLCNAWPARWRKQGRMETAPFTAPDV
                     DRLLLDWLNDAQQYQWRTHGQLDFAVSLSGTRRLRASAFTHQQGTSLAIRLLPERCPD
                     LAEIQTPPIVPALLASENGLILVTGATGCGKSTTLAAMVGHLNQHADKHILTLEDPIE
                     YRYTSKRCLIQQREIGQHCATFAAGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKEPVRSQLAGSLRAVLSQKLEVDRQDGRVAL
                     FELLINTPATGNLIREGKLHQLAHVIQTGQQQGMMTFAQSAQWRQAQGRL"
     gene            6942..7628
                     /locus_tag="OPY25_002702"
     CDS             6942..7628
                     /locus_tag="OPY25_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCS0928284.1"
                     /translation="MSSQPNQSLIDGIRCLQYLVSSDRAIGCRELARLMDINTTRVNR
                     LLMTMASIGLTMQDEHRRYLPGPGIHALAAQAIRGSALFSHALPILERHAPRDIVVAL
                     GVLWEDQIIYIYHSTPGAQGSQALAGFRMCLAWQSVPGVALLAAESDEALMQRFSPEQ
                     WRNLAPHVAQQRQRGYVLWHHADGEVSMAQPLDKHAAALAFAGMWRIDEAEAAARLQA
                     LKALNQLIAQ"
     gene            complement(7675..8091)
                     /gene="ruvX"
                     /locus_tag="OPY25_002703"
     CDS             complement(7675..8091)
                     /gene="ruvX"
                     /locus_tag="OPY25_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCS0928285.1"
                     /translation="MSDTLLAFDFGTKSIGVAIGQRITGTARPLPAIKAQDGTPDWTL
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVTVTLHDERLSTVE
                     ARSGLFERGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(8091..8654)
                     /locus_tag="OPY25_002704"
     CDS             complement(8091..8654)
                     /locus_tag="OPY25_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HCS0928286.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIINKPLE
                     NLQIEGILEKLKITPEPRDSAIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDN
                     TVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKT
                     PIAERWREAAKLIGIDILTMPGVAGHA"
     gene            complement(8870..9817)
                     /gene="gshB"
                     /locus_tag="OPY25_002705"
     CDS             complement(8870..9817)
                     /gene="gshB"
                     /locus_tag="OPY25_002705"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HCS0928287.1"
                     /translation="MIKLGIVMDPIAHINIKKDTSFAMLLEAQRRGYELHYMEMADLY
                     LINGEARACTRTLSVEQNYDKWYEFGSEQEIKLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEEGTLIVNKPQSLRDCNEKLYTAWFADLTPETLVTRNKAQLKAFWEKHGDIIMK
                     PLDGMGGASIFRVKEGDPNIGVIAETLTELGNRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLSESDWEIARRVGPTLKAKGLIFVGLDIIG
                     DRLTEINVTSPTCVREIEAEYPISITGMLMDAIEARLAK"
     gene            complement(9837..10568)
                     /gene="rsmE"
                     /locus_tag="OPY25_002706"
     CDS             complement(9837..10568)
                     /gene="rsmE"
                     /locus_tag="OPY25_002706"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013319572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCS0928288.1"
                     /translation="MRIPRIYHPELLTSGTQISLCEDAANHIGRVLRMGAGQALQLFD
                     GSNQVFDAEIISASKKSVEVQVMKGEIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDNERLNKKRQQWQKIAIAACEQCGRNRVPEIRPPMALEAWC
                     AEQDSGLRLNLHPRAHASINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            complement(10645..11352)
                     /gene="endA"
                     /locus_tag="OPY25_002707"
     CDS             complement(10645..11352)
                     /gene="endA"
                     /locus_tag="OPY25_002707"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HCS0928289.1"
                     /translation="MYRNFSFAAALLAAAFSGQALADGINNFSQAKAASVKVNADAPG
                     SFYCGCQIRWQGKKGVVDLESCGYKVRKNENRARRIEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYCKMESDMHNLQPAIGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKAK
                     LAEPPARARGAIARTYFYMRDQYQLKLSRQQTQLFNVWDKQYPVTAWECERDARIAKV
                     QGNHNPYVQRACQARKS"
     gene            complement(11448..11945)
                     /locus_tag="OPY25_002708"
     CDS             complement(11448..11945)
                     /locus_tag="OPY25_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HCS0928290.1"
                     /translation="MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRG
                     TSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWM
                     MESVLGVPARRTHQFALQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGE
                     PLVAG"
     gene            complement(12024..13418)
                     /gene="galP"
                     /locus_tag="OPY25_002709"
     CDS             complement(12024..13418)
                     /gene="galP"
                     /locus_tag="OPY25_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HCS0928291.1"
                     /translation="MPDNKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIT
                     DEFQITAHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLIISRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYSGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFHDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGILLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAIGMGIL
                     GTMMHIGIHSPSAQYFAIAMLLMFIIGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNNLGNANTFWVYAGLNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            complement(13911..15065)
                     /gene="metK"
                     /locus_tag="OPY25_002710"
     CDS             complement(13911..15065)
                     /gene="metK"
                     /locus_tag="OPY25_002710"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCS0928292.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLN
                     TSTKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPAEQLILLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGRENFPWEKTDKAQLLRDAAGLK"
     gene            15121..15420
                     /locus_tag="OPY25_002711"
     CDS             15121..15420
                     /locus_tag="OPY25_002711"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928293.1"
                     /translation="MTEDSTMSLKVTNTGSLSVNQYGWINIWTAILGHFFAQFPAFFE
                     GRRNVGQNQAVNVSDNADIMRIYALLFFCVLGIKRDARLIQKHTTFSSCRHFQPG"
     gene            complement(15417..15581)
                     /locus_tag="OPY25_002712"
     CDS             complement(15417..15581)
                     /locus_tag="OPY25_002712"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928294.1"
                     /translation="MGITSAGMQSRDADCGRHARTRTMRQIQQNTTVHYLVSPPRPPR
                     KTNPQAKATF"
     gene            15715..15846
                     /gene="yqgB"
                     /locus_tag="OPY25_002713"
     CDS             15715..15846
                     /gene="yqgB"
                     /locus_tag="OPY25_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HCS0928295.1"
                     /translation="MKKKPVAQAEHQRYLLENPLVYGLLSRLRIAIVVNCFTLANKN"
     gene            15855..17831
                     /gene="speA"
                     /locus_tag="OPY25_002714"
     CDS             15855..17831
                     /gene="speA"
                     /locus_tag="OPY25_002714"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HCS0928296.1"
                     /translation="MSDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAE
                     DAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHF
                     RDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE"
     gene            18059..18979
                     /gene="speB"
                     /locus_tag="OPY25_002715"
     CDS             18059..18979
                     /gene="speB"
                     /locus_tag="OPY25_002715"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HCS0928297.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHHRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLSAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPHHSVQIGIRTEFDKDNGFTVLDACQVNDRGVDDILAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(19080..19838)
                     /locus_tag="OPY25_002716"
     CDS             complement(19080..19838)
                     /locus_tag="OPY25_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HCS0928298.1"
                     /translation="MKIRALLLALGMATVLTGCQNMDSNGLLSSGAEAFQAYTLSDAQ
                     VKALSDQSCQELDSKAKIAPASSEYTKRLAKIAAALGDNINGQPVNYKVYETKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
                     GGVVGSLSQSQLGDLGEKLVNSQFSQRQESEADDYSYDLLRKRGISPAGLATSFEKLA
                     KLEAGRQSSMFDDHPASAARAQHVRDRMSADGIK"
     gene            20114..22105
                     /gene="tkt"
                     /locus_tag="OPY25_002717"
     CDS             20114..22105
                     /gene="tkt"
                     /locus_tag="OPY25_002717"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCS0928299.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LNHNPTNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMSELQNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHFTYVFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAKRFEAYGWHVIRGIDG
                     HDADAIKRATEEARAVTDKPSLLMCKTIIGFGSPNKQGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYEKAFPQEAAEFTRRMKGDMP
                     ADFNAKANEFIAKLQANPSKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGIALHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPQIIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVSARVAIEAGIADYWFKYVG
                     LNGAIVGMTTFGESAPAELLFEEFGFTVDNVIAKAKALL"
BASE COUNT         5112 a         5840 c         6096 g         5095 t
ORIGIN      
        1 cttaaagcta aaagctttcc ggaaccccca gcctagctgg gggttttcca tagacaacaa
       61 tggcgcagat cgtatctgcg cctttttatt ctgttttttc ctgcattttg ttatccatct
      121 ctaaaaaata ctctctgtcg gatatatatc gctggttaat cgtatggcgt cacattattc
      181 gtctgcaata tagggataat gcgaccagtt gacataactg gagatataac atggagtttt
      241 tcaggaaaac ggcattagct gctctggtaa tgggtttcag cggcgcagcg ttcgctttac
      301 cgaatatcac catcttagcg accggcggaa cgatcgctgg cggcggtgat tcagcaacaa
      361 aatcaaatta tacggcaggt aaagtcggcg tcgaaaatct ggtggatgcc gttcctcaat
      421 tgaaggacat tgcggtagtg aaaggcgagc aggtcgttaa cattggctcg caggatatga
      481 acgatgaagt ctggctcacg ctggcgaaaa aaatcaatac cgagtgcgac agcaccgacg
      541 gtttcgtgat cacccacggt actgatacga tggaagagac cgcttatttc ctcgatctga
      601 ccgtgaaatg caataaaccg gtggtactgg tcggcgcgat gcgtccttcc acgtcaatga
      661 gcgcagatgg cccgttcaac ctctataatg cggtagtaac agcggctgat aaacagtctg
      721 ccaaccgcgg cgtgctggtg gtaatgaatg ataccgtcat ggacggacgc gacgtcacta
      781 agaccaatac gactgacgtg gcgacgttta aagcggttaa ctacggcccg ctgggttata
      841 tccacaacgg taaaattgac taccagcgta cgccagagcg taaacatacc acctccaccc
      901 cgttcgacgt gtcgaagctg accgcgttgc cgaaagtcgg tatcgtttat aactatgcga
      961 atgcgtccga tctgccggca aaagcgctgg tagacgcggg ttatgacggg atcgtgagcg
     1021 caggcgtggg taacggcaac ctgtataaaa cggtctttga taccctagcg accgccgcgc
     1081 acaacggtac ggtagtggtg cgttcttcac gtgtgccgac tggcgcaacc acgcaggatg
     1141 cggaagttga cgatgcaaaa tacggctttg tcgcttccgg cacgctgaac ccgcaaaaag
     1201 cgcgtgtctt actgcaactg gcgttaaccc agactaaaga tccaaaacag atccagacga
     1261 tgttcaatca gtattaaaga taatgccccg gtcggaaggc cggggccatc tttggaagac
     1321 ctctcgcaca accaacacta ttatcttgct aattatcatc ctggttatga taattgtggg
     1381 cgtcatgtct ctggacggga ggtccacaag tggttcgaca atggattgct ggcgcagcgc
     1441 tgtttgccct gatttcaggc tatagttggg cagaggttgc tcaaccctcc gataacatct
     1501 taaaagaaca gtttagtaag cagtaccacg gcatacttaa actggattcc attaccttaa
     1561 aaaatcttga ttcgacgggc aatcaggcca cctggtctgc cgaaggggat atttcttccc
     1621 gtgaagatat gtataccggc gttggtatgg cggcggatta ttattttgtt gaaaaaacct
     1681 ggaccaaaga tcgtcccgtt aaattttctg ccatgttaac cagcaaaggg acgccagcct
     1741 ctggctggac ggtgagctat tactcattac aaatggcagc cagcgatcag ggccgggcta
     1801 ttgacgacat taaaacgaat gataaatacc tgatcgtcaa cagtgatgac tttaactatc
     1861 ggtttggcaa cattgaagcc tcctggcgtg cgcagaaagc gtcgatcccc ggtcttgaag
     1921 aacaactctc tgccctggat aagaaaatag cggtagctaa aaaagaagcg gacgcatatt
     1981 ggggaaaagg cgctgatggg aaaccgttga cccgcgccga ggcgtttaaa aagacgttaa
     2041 aagagcgcga tgattatgta aaagccaacg atagcagcgt atatgccgag aaatacgaaa
     2101 aagaggtcta tcaaccagca ttagacgcgt gtcgtaagca gagtgagccg tgcaatgaag
     2161 cggctattca gcagaaaaga gatttagaca tacacgagca acggcggcag gtatttttga
     2221 aatcagaaga gctgcgtcga aaagcgcaga atgactggat aacgttagag aaagggcaat
     2281 atccgctgaa tatagcggta cagaaacttc agatgcaaca gagtgatatc cgcatgaaaa
     2341 tcatggatat taatgacggt tacgagcgct ggaaaaaaga tacggacgat ttgcgtcgta
     2401 aaggcgttat taaataatgc gcttgctggt ggcgcattaa ccgccacagg tcggtaagcg
     2461 tcgcgccatc aggtatttta cccgctggcg cgacaggctt atccttgtta ttccgcgaga
     2521 aacaactcaa gaagagagtt taaaaacagt ttaccgtgac gggtaatctg ccagtattgc
     2581 tcgcattctg tcaggtagcc ctgggcaata gcctcgtcga ttggctgacg aataaccgct
     2641 tccgtaagcc cggtgtagtc gacaaattcg gcgcgaggcg cgcgctccag caaccgaaaa
     2701 cggttcataa agaactcaaa gggtttatcg tcatcactca cgtcacgctg gctttccagg
     2761 taacgtccct gcatataacc gcgtgggtga cgggttttgg tggtgcgcaa gatcctgccg
     2821 tccgggaagg tgactttacc gtgggcgccg cagccaatac ccagatagtc gccaaagcgc
     2881 cagtagttca gattatgctg gcactgataa ccgggtttgg cataggccga cgtttcgtat
     2941 tgctgatagc ccgcggcggt taataactgg tggccctgct caaagatatc ccacagcgcg
     3001 tcatcgtccg gtaaaaccgg cggacgcgaa ccgaacaaag tgttgggttc aatcgtcaat
     3061 tgataccatg agagatgcgg cggattaagc gcaatcgcct gtcgcaaatc attcagcgcc
     3121 tcttccagcg tttgatccgg caatccatgc atcaagtcga ggttaaagct gcgtagccca
     3181 agcccatttg ccagtcttgc tgcccgcatc gcctcttgtg gaccgtgaat acggccaaga
     3241 cgtttcagct taggctcact aaagctctgc acgccaatgg agatccggtt tacgccggcg
     3301 cgctgatagt cgatgaagcg gtcggcttcg accgtgccgg ggttcgcttc catggtaatt
     3361 tccgcatccg ccgccagatt caggcgcgca cgcacgccgt ccagcagcgt ttgcatcgcc
     3421 ggcccggaaa gcaggcttgg cgtaccgccg ccaataaaaa tggtctttac ttcacgccct
     3481 tgcgcccaag cgacgtcggc atccagatcg cttaacagat gctggacgta gtcgtcatgc
     3541 ggcacctcgc ccttcaacgc atgggaattg aagtcgcaat atggacattt ttgtacacac
     3601 cagggaatat gaatataaag actgagcggc ggtagtttag ccattgcgta acgcatccag
     3661 cagcagcttg agcgcttgtc cacggtggga aatcgcgctt ttttcttcac gggtcagttc
     3721 tgcggcggtt ttgccttcag acggtacgaa gaaaatggga tcatagccaa atccgccatt
     3781 tccggccgcc tggcgagtaa tgacgccagg ccagctaccg tgacagacta tcggtgtggg
     3841 atcttcggca tgacgcaaat aaaccagtac acaatggaat cgcgcctggc gtttgtcgtc
     3901 cggaacatct cgtagagtat gcagcagttt ttccagattt tgctgatctg tcgcgttttc
     3961 gccagaatag cgcgcggaat agatacccgg cgcgccgcct aaaacgtcaa cggccagacc
     4021 ggagtcatcg gcaatggcgg gcagaccggt cattttagcg gcatggcgcg ctttgagaat
     4081 cgcgttttca ataaacgtca ggccggtttc ttccgcagag tcaacgccca gtttcgtttg
     4141 cgctaccaca tcaagcccaa aatcgcttaa cagcgacgcg agctcgcgca ctttaccggc
     4201 gttgccggtt gcgagaacaa ctttttgcat ggaataccta ctcagttaac gccgcaattt
     4261 ccggcgggat ctgttgcggg tgaataattt ttacctgttt gtgacggccc agctcgcctt
     4321 tttcgatgac gatctgactt ttcgccacgc gaaactgttt accgagaaac ttggtcagat
     4381 ggctgtttgc ctgaccgtca accggcgggg cggtaatggc gactttcacc tcgtcgccat
     4441 gtaaacccac aatactgtcg cggctggctt tcggctgaat ataaagccgt aacaccagac
     4501 cgtcttcgca gcgagtcaca gcactcatag cgccatccac agccccggca gcaacatgtt
     4561 gcctgtcgct tgtaagactt cagcgatccc catattaacg acatacagca gcagcaccag
     4621 aaccatcggc gagaagtcga tgccgcccat cgcaggcagt atacggcgaa tcgggctgag
     4681 cagcggctcg gcaagctgaa tcaatacata ttcaatcggg ctacgaccct ggctcaccca
     4741 gctcatgata gccatgacca gcagcaccca gaagatcagc aggccgattg ttttaagtaa
     4801 gataagcacc gcggcaatcc agataatcgc ctgaaacgta attaccttaa acagcactat
     4861 cgccttaata acgctaagaa taaacgccac cagcagggaa gcgctgtcga tcggccccat
     4921 tggcgggata atacgacgca gcggtccgat gatgggctgc gtaattttca ccacgaactg
     4981 ggaaaaaggg ttgtaaaagt cacagcgggc ccactgcatc cacacgcgca ataatagcac
     5041 catggtatac agctcaatta ccgttgagag caggaaggtc aacgtattca tggcgttcct
     5101 cagttttcct taattttttg tgtaatcacg agcaccaaag atagcggtgc cgatgcgcac
     5161 cattgtgcta cctgccgcaa tcgcggcttc catatcgtcg ctcataccca gagataaggt
     5221 atcaacgtca gggtagcgcg ctttcagccc ggcaaatgct acagccattt gacgtgcgac
     5281 ttcaaactgc cttacataat ctgactctgg cgccgggatc gccatcagtc cgcgaagccg
     5341 cagacgcggc agtgtagcca ccgcagcggc cagctcatcc agttccgcca gcggaatgcc
     5401 tgatttgctg ttttcatcgc tgatattaat ttggatcaga acatttagcg ccggcagatt
     5461 atccgggcgc tgttcgctca gccgcgaggc gatacgcagg cgatcgatgg tatgacacca
     5521 gtcaaaatgc tcggccacca gccgactttt gttggactgt aaagggccaa taaagtgcca
     5581 gtgcaggcct tccactttcg cttcctgaaa gtggcggatt ttttccaccc cctcttgtac
     5641 ataattttca ccaaatgccc gttgtccggc ggcaatggct tctgcgatgt cgctcgcagg
     5701 tttggtttta ctcactgcaa gcaacgtaac ttcttctgaa gagcggccac aacgcgtcgc
     5761 cgcggcggag attttgtccc ggatgtgtgc caggttatgc gcgatatcgt tcattttccg
     5821 aggatgttta tatgaatatg gaagaaattg tgacgcttag tgtaaagcat aacgtctcgg
     5881 atctacacct gtgtaacgcc tggcctgcgc gatggcgcaa acaaggacgc atggagaccg
     5941 cgccttttac cgcgcctgat gtcgacaggc ttctgcttga ttggcttaat gacgcgcaac
     6001 aatatcagtg gcgaacgcac ggtcagcttg atttcgccgt ctcgctgtct ggcacgcggc
     6061 gcctgcgcgc cagtgcgttc acacatcaac agggaacgtc gctggcgata cggctattgc
     6121 ccgagcgttg tcctgatctg gcggaaatcc agacgccgcc gatagtaccc gcactgcttg
     6181 ccagcgagaa cggactgatt ctggtcactg gcgctactgg ctgcgggaaa tccactacgc
     6241 tggcggcgat ggtgggacat cttaatcaac atgccgataa acacatcctg acgctggaag
     6301 atcctattga gtaccgttac accagcaagc gttgcctgat acagcagcgg gaaatcggcc
     6361 agcattgcgc cacttttgcc gccgggctgc gcgcggcgtt acgtgaagat cccgatgtca
     6421 ttttactggg agagctgcgt gacagcgaga ccattcgcct ggcgctgacg gcggcggaaa
     6481 cggggcatct ggtactggca accctgcata ctcgcggcgc ggcgcaggcg gtggaaagat
     6541 tagtggatag ttttccggcg caggaaaaag aaccggtacg cagtcaactg gcgggtagtc
     6601 tgcgcgccgt actatcgcaa aaactggagg tcgacagaca ggatgggcgc gtggcgttgt
     6661 ttgaattact gattaatacg ccagccacag ggaatttgat ccgtgaaggc aaactccatc
     6721 agttggccca cgtgatacaa accgggcagc agcaggggat gatgacattc gcccagagcg
     6781 cgcaatggcg tcaggcgcag ggacggctgt agcgaagatg gcggcgtagg gaaggggaag
     6841 tgttgactgg cgcggtggat tgaacggcat acaggcttgt atcctggcga accggcgtta
     6901 aaatcgcagc tttgttaaaa ccacagcgaa gtcatttaac gatgtcatca caaccgaatc
     6961 aaagcctgat agatggcatt cgctgtctgc aatatctggt ctccagcgac cgtgctatcg
     7021 gatgtcgcga gcttgcccgg ctgatggata ttaataccac gcgcgttaat cgcctgttaa
     7081 tgacgatggc ctctattgga ctcacgatgc aggatgagca ccgacgctat ttacccgggc
     7141 caggcattca tgctttggcg gcgcaggcga ttcgcggttc agcgctgttc tcccatgcgt
     7201 tgcctatcct tgagcgacat gcgcccagag acatcgtggt ggcattaggc gtgctatggg
     7261 aagaccagat tatctatatt tatcactcta cgccgggggc gcagggaagt caggcgctgg
     7321 cggggtttcg catgtgcctg gcctggcagt cggtacctgg ggtggcgtta ctggcggcag
     7381 aaagcgatga ggcgctaatg cagcgtttta gtccggagca gtggcgtaat ctggcaccgc
     7441 atgtggcgca gcagcgccag cggggatacg tgctgtggca tcacgctgat ggtgaagttt
     7501 ctatggcgca accgctagac aagcacgccg cagcgctggc ctttgcggga atgtggcgga
     7561 ttgatgaggc ggaggcggct gcgcgtttac aggcgttgaa ggcattaaac cagcttattg
     7621 cccagtaagc ctggcaaccg tgaccgcgtt atccgcctgc tgacaaaaac ggctttaata
     7681 cccctgttca aaatagcttt cgaggataat cacggcggag gccgagtcca ctttgccttt
     7741 attcagcgcg cgatacccac ctcgttcaaa cagaccggag cgtgcttcaa cggtgctgag
     7801 tcgttcatcg tgtagcgtga cagttacccc gaagcgccca tgaatacggt tggcgaattt
     7861 acgggcgcgc gccgtcagcg gttgttcagt gccatccata ttgagcggta gcccgacaat
     7921 aatttcgtcc ggctgccact ctttcagcaa acgttcaatg agcgtccagt cgggcgtgcc
     7981 gtcctgtgct ttgattgccg gaagcggacg ggcggtgccg gtaatgcgtt gtcctattgc
     8041 aacgccgatg ctttttgtgc cgaagtcaaa ggccagtaag gtgtcgctca tcaggcgtgc
     8101 cccgcaacgc caggcatggt cagaatatca atgccaataa gttttgccgc ttcgcgccag
     8161 cgctcggcaa tgggcgtttt gaacaaaata ttgagatcgg cgggcgcggt aagccaggcg
     8221 ttatcaagca actcttgttc aagctggcct ttatcccagg aggcgtagcc cagcgcgacc
     8281 agcacatcgg aaggctgttg ttgggtacct aacgtttcca gcacatcgcg ggaggtggta
     8341 atcacggtat tgtctgagat acgaatgctg gaggcgaaac gtgacggcgg agtatggaga
     8401 ataaatccgc gatcttccgc cagcgggccg ccgagcatca cggctttatc aagacgaatt
     8461 gccgaatcgc gcggttccgg cgtaattttt agtttttcca gaatcccttc aatttgcaga
     8521 ttttccaaag gcttattaat aataatcccc atagcgccgt cctggttgtg ctcgcaaata
     8581 tacaccacgg aacggcggaa aatcgggtcc tggagcgcag gcatggcaat aagaaagtga
     8641 tgctgtaaat tcattgtcag aggttctgtt tcctggttca aaaaaacgac agcgttcagt
     8701 atgtggggaa agcggacggt tgtcactcat ataagccgtc ttttgccaaa ggacggcggc
     8761 cttatcgggc aatagactgc cggatggcga tgctgacgcg ccgccttatc cgaccggggc
     8821 ggcgtgattg ctcaggcccg gtaagcgcac gccaccgggc aataaacttt tacttcgcca
     8881 gacgcgcttc gatggcgtcc atcaacatcc cggtgataga gatcgggtat tccgcttcaa
     8941 tttcacgcac gcaggttggg ctggtcacgt taatttccgt taagcggtcg ccgataatat
     9001 ccagaccgac aaaaataagc cctttggctt taagcgttgg tccaacgcgg cgggcgattt
     9061 cccagtcgct ttcgctcaac ggacggggtt cgccgcgacc accagccgct aggttgccgc
     9121 gggtttcgcc gccctgcgga atacgcgcca ggcagtaagg caccggctcg ccgtcgacga
     9181 ccagtacgcg cttatcgcca tctttgatcg cgggcagata gttctgcgcc atgcagtagc
     9241 ggttgcctag ctcggtcagc gtttcggcga taacgcctat gttaggatcg ccttccttaa
     9301 cgcggaaaat ggacgcgccg cccataccgt ccagcggttt cataatgata tcgccgtgct
     9361 tttcccaaaa cgctttgagc tgcgctttat tgcgcgttac cagcgtttcc ggcgtcaggt
     9421 cggcaaacca ggcagtatac agtttttcat tacagtcgcg caggctttgc ggtttgttga
     9481 cgataagcgt cccttcctct tcagcgcgtt ccagaatata ggttgcataa ataaactcgg
     9541 tatcaaacgg cggatctttg cgcatcaaaa tgacgtccag atcggcgagt ttaatctcct
     9601 gctcgctgcc gaactcgtac catttatcgt aattttgctc cacgctcaac gttcgcgtgc
     9661 aggcgcgggc ttcgccgtta atcagataaa ggtcggccat ctccatataa tgaagttcat
     9721 aaccacgacg ttgggcttcc agcagcatag cgaaactggt gtctttcttg atgttgatgt
     9781 gtgcgatggg gtccatcacg atgccgagct tgatcattat tttctccgtt aacgcttcat
     9841 cctaagtcgc caaaacgcac ctgtagcgcg gtaatggcgg tgagcgcggt tgtctcagta
     9901 cgcagaacgc gaggtcctaa cagaatatca gtaaactgat agcgcgcggt catcgcgatt
     9961 tcgtccgccg acagcccgcc ttccgggccg atcagcagtc ggacgcgttc aaccggcagc
    10021 ggcagagtgt tgatgctggc atgggcgcgc ggatgaagat tgagcctcag cccggaatct
    10081 tgctcggcgc accaggcttc cagcgccatc ggcgggcgaa tttccggcac ccggttacgc
    10141 ccgcattgtt cgcaggcggc gatggcgatc ttttgccact gctggcgctt tttgttcaga
    10201 cgttcattat ccagtttaac gccacagcgc tcagagaaca gtggcgtaat gaggcttaca
    10261 cctagttcga tcgatttctg gatagtaaat tccatttttt caccgcgcga catcacctgg
    10321 cccagatgga tatgtagcgg cgattcacga tcgtcgattt cgcctttcat cacttgcact
    10381 tcaacgcttt tcttactggc gctaatgatt tcagcatcga atacctgatt gctgccgtca
    10441 aacagctgta acgcttgtcc cgctcccatg cgcagtacac gaccaatatg gttggccgca
    10501 tcttcgcata acgaaatctg cgtaccggac gtcaacaatt cagggtgata aatgcgggga
    10561 atacgcataa taaaaaaatc cgcgtcatgg ccccggcgtt tggctatcca gggcatgggt
    10621 taacaagaat cccgctagtg taggttagct ctttcgcgcc tggcaagcgc gttgcacata
    10681 gggattatga ttaccctgga ccttcgcgat acgcgcatcg cgctcgcact cccaggcggt
    10741 aacggggtac tgcttatccc agacgttaaa aagctgcgtt tgttggcggg aaagtttcag
    10801 ttggtattgg tcgcgcatat aaaaataagt gcgggcgatt gcgccacggg cgcgggcggg
    10861 cggctcggcg agcttcgctt taaaatccac tttcatggcg cactgcccgt actgaccttc
    10921 gccgccgttc cactggctat acataaagtt gccgcgatcg ccattcactt cgccaatcgc
    10981 gggttgcagg ttatgcatat cgctttccat tttgcagtag accgggtctt tagcgcagtt
    11041 ttttcgcccg ccgtcctgcc agcactggcg ctgatgaccg aattgccagg cggggacaac
    11101 gtgctcccac tcaatgcgtc tggcgcgatt ctcgttttta cgcaccttat agccgcagga
    11161 ctccaggtct acgacgcctt ttttaccctg ccagcggatt tggcacccgc agtaaaagct
    11221 gccgggcgcg tcggcattga ctttgacgct cgccgctttg gcctgagaaa aattgttaat
    11281 gccgtcggcc aatgcctggc ctgaaaacgc tgcggccagc aacgcagcag caaaagaaaa
    11341 attacggtac attgcacact ccatagcaaa acgagcccgc aacgtagcga aagttgtgtc
    11401 tgtatgcaat cagtccgctc aggaaagttc ccggacgttt cggggaacta cccggcgacc
    11461 agtggttcgc cgcagtgaac gcaacgataa accgcttcgc cgcgtaccac acggttatga
    11521 cggcggacgg tgagttgatg ttgctggcat tggcaatggt agggaaaggt attgcgccgt
    11581 acggattgca gcgcaaattg atgagtacgt ctggccggaa cgcccagcac gctttccatc
    11641 atccacttcc attccttgcc atgcggagcc ttgcgtccga agtgcttcca caccaacaga
    11701 tgcgccagtt catgcggcac gacctctgca ataaaggtgt cgatgttttc cagcagtaac
    11761 accgggttga ggcggatttc gtagctctcc agccaggcgg tgcccgccga ggtgccgcgt
    11821 tgcgtataca ccagtttcgg ctccggataa tgtctatcga gcttgaggtt cgcctgggcg
    11881 agattttccc gcagacggcg catcacggcc tgctggatag cgatagggag acgaggggtt
    11941 ttcatagcgg cagagaatag tgcgacggaa gagggactgc aagaaaaacg cttcctcctg
    12001 tggcaggagg aagcgtggag ggattagtcg tgggcgccga tttcgcgcag tttacgacct
    12061 ttcatcaggt tacgttcaat gtgttccagc gaaacgtgtt tggtttccgg caccagccac
    12121 agggtcagca ggataaacag cacgttcagg ccagcgtaga cccagaaggt gttggcgtta
    12181 cccagattgt tcagcatggt caggaacgtt gcgccgacga tcatattggc gatccagttg
    12241 gtcgcggtgg agcaggtgat gccgaaatcg cggcctttga gcggctggat ttcggagcac
    12301 agtacccaaa tcagcggacc agcgctcatc gcaaatccaa tgatgaacat cagcagcata
    12361 gcgatagcga agtattgcgc agacggtgaa tggatgccga tgtgcatcat cgtacccaga
    12421 atccccatac caatcgccat gaccaggaag cccagcgtca gggtcggctt gcggccccag
    12481 cggtcaacca ggccgatagc gatgaaggtt gccagcacgt tagtcagacc aacaataacg
    12541 gtgccccaca tctgctccgt ggtattcgtg taccccgcca gttcgaagat tttcggcgcg
    12601 taatacatga tgacgttcat cccggtaaat tgctgcatta cctgcaacaa aatgccaaga
    12661 aacacggcgc ggcggaagtt gctgttctct ttgaacagcg cccaaccgct ctgtttaacc
    12721 tgcaaacttt cgcgaatttc atcgagctca cgttttgctt ccgcactggt gtcacgcagg
    12781 cgcaacagga cgcgttcagc atcatggaaa cggcgtttcg ccgcaaacca gcgcgggctg
    12841 tccggcagga agaagacgcc gatcagcagc agaatggccg ggatgatgat cacgccgagc
    12901 atccagcgcc atgcgccgct gtagctgaac gcggtatcgg acagataagc gcccagaatc
    12961 ccgatggtga tcatgagttg gtacattgag atcatactgc cgcgaatttt ttccggcgcg
    13021 atctcggaca ggtacaacgg tgcagtgtag gaagcgacgc cgacggccag acccagcagc
    13081 acgcgagaaa taatcaggac ttcaacgtta ggcgccgcag cggagaacag cgaaccggcg
    13141 acgaacagga tagcgccgat catcaggctt tttttacgac ccagcttaaa ggagagccag
    13201 ccgctgccga cagcgccgac ggccgcgcca aacatcatgg agctgaccac ccattcctga
    13261 gtgtgtgcgg taatctgaaa ctcgtcggta atgaagggta aagcaccggc gataacgccg
    13321 atatccaggc caaaaagtaa tcctgccagg gctgcaagaa agcagacaaa aaatgtcatg
    13381 gccttgttgg aacgcccttg ttttttattg tcaggcatta tgccctccgg ttgggttagc
    13441 aattttatcg atgttaagag taggtgagta cgccgtaaaa agatgtgagg ctaatcacaa
    13501 tggtgtaatc gtttacacta ctatttatct cggtgattat ttaattatct gaaaaataat
    13561 agttttaata atcttataac cctatcaatc gcctggtatt cagacaaagc tgaaaaacta
    13621 tgtaacattt tcatcgcaga gttagcatac cgacagtgag gtggtcagtt ctcaatgaaa
    13681 atgaatgtaa ccgctttcat agctgctgaa actgaatgat gaaaagtgta gtcgaagaaa
    13741 cgaaagagga gagcggattg tgctgcgcat cacaaaaagg tcagtataaa tacacgctgg
    13801 aacatctaat aacgttgcgt gtatcagcaa tgataaaggc cagcagggcg ctggccttga
    13861 taagtacggt atggtttacc tgactgaaaa acagcgtcag gcgcgggcga ttatttcaga
    13921 ccggcagcat cgcgcagcag ttgcgctttg tcggtttttt cccatgggaa gttttcgcga
    13981 ccgaagtggc cgtaagccgc agtttctttg tagatcgggt gcagcagatc cagcatctga
    14041 atcaagccgt acgggcgcag gtcgaagaat tcgcgcacca gcagaatcaa ctgttcagca
    14101 ggcacttttt cagtaccgaa cgtttccacc atgatggacg tcggctccgc tacgccgata
    14161 gcgtaggaga cctggatttc acagcgatcc gccagacctg ccgccacgat gtttttcgcg
    14221 acataacgcg cagcgtaagc tgcagaacgg tcaactttag acggatcttt accggagaag
    14281 gcgccgccgc cgtgacgcgc cataccgccg taggtatcaa cgatgatctt acgaccggtc
    14341 agaccacaat cgcccatcgg gccgccgata acaaaacgcc cggttgggtt gataaaaaac
    14401 ttagtggacg tatttaacca ttcagacggc agaatgggtt tgatgatctc ttccatcacc
    14461 gcttcttgca gcgatttttg gtcgatatct tctgcgtgct gcgtagagag aaccacggcg
    14521 tcgataccga cgattttgcc gtcgtcatac tggaaagtga cctggctttt tgcatccgga
    14581 cgcaaccatg gcagggtgcc atttttacgc acttcagcct gacgctgtac cagacggtgc
    14641 gcgtaggtga ttggcgcagg catcagtacg tcggtttcat ttgtcgcgta gccaaacatc
    14701 aggccctggt cgcccgcgcc ttgttccagc gggtctgcgc ggtcaacgcc ctggttgata
    14761 tccggagact gtttgccaat tgcgctcagt accgcgcaag agttggcgtc aaagcccatg
    14821 tcggaatgca catagccaat ttcgcgcacc gtattacggg taatctcttc gatatcgacc
    14881 caggcgctgg tggtgatctc accgccaact aaaaccatgc cggttttaac gtaggtttca
    14941 caggcgacgc gtgctttcgg atcctgttgc aggatagcgt ccaacacggc atcagagatt
    15001 tggtctgcga ttttgtcagg atgcccttct gatacggact cagacgtaaa aaggtgtttt
    15061 gccatattta atttcaccta aggagaattt agttagctca aactgttgtg cggaatagtc
    15121 atgacagaag attctaccat gagtctgaag gttactaaca ctggcagtct gagtgttaat
    15181 cagtatggat ggattaacat ctggacggct attttaggtc acttcttcgc ccaatttcca
    15241 gctttttttg aaggccgtcg caatgtcggt caaaatcagg cggtaaacgt ttctgataat
    15301 gctgacatta tgcgcattta tgctttgctt tttttctgcg ttctgggtat aaaacgcgac
    15361 gcgcggctca tacaaaagca cacgacgttt tcttcgtgtc gccacttcca gccgggttaa
    15421 aacgttgctt tggcttgtgg gttcgtctta cgaggcggcc gtggaggtga tacgagataa
    15481 tgaaccgttg tattctgctg aatctgtcgc atcgttctgg tgcgcgcatg tctcccgcaa
    15541 tctgcatctc tgctttgcat acctgccgat gttataccca tctcggcgct tctcaggatt
    15601 ccagagccgg caatggcgct gaagactgaa caagggcgct cttgttaacg caagagtttt
    15661 ctcgtggttt cgccgaaccg ttatctgtga gttcggttac gtgtttacaa tgatatgaaa
    15721 aagaaaccgg tcgcgcaggc ggagcatcag cgctatctgc tggaaaatcc gcttgtctat
    15781 gggttgttat cgcgtcttcg gattgcgata gtagtcaact gttttacact tgctaataaa
    15841 aattgaggtt cgctatgtct gacgacatgt ctatgggttc gccttcgtca gcaggcgaac
    15901 agggtgtact acgctccatg caggaggttg caatgagctc ccaggaagcc agcaagatgc
    15961 tgcgcactta caatattgcc tggtggggca ataactacta cgacgtcaac gagctgggcc
    16021 atattagcgt atgccccgat cccgacgtac cggaagcgcg tgtcgatctt gccaaactgg
    16081 tgaaagcgcg cgaagcgcaa ggtcagcgtc tgccggcgct gttctgcttc ccgcagatcc
    16141 tgcaacaccg tttgcgttca attaacgcgg cgtttaagcg tgcgcgtgaa tcttacggtt
    16201 ataacggcga ctacttcctc gtttatccga ttaaggtcaa tcagcatcgc cgcgtgatcg
    16261 agtcccttat ccattccggt gaaccgttgg ggctggaagc ggggtcgaaa gcggaattga
    16321 tggcggtgct ggcgcatgcc ggcatgaccc gtagcgtgat cgtctgtaat ggttataaag
    16381 accgtgaata tattcggctg gcgctgattg gcgagaagat gggccataag gtttatctgg
    16441 tcatcgaaaa gatgtctgaa atcgcgattg tgctggaaga ggccgagcgc ctgaacgtgg
    16501 ttcctcgcct gggcgtgcgt gcgcgtctgg cctctcaggg gtccggtaag tggcaatcct
    16561 ccggcggcga aaaatcaaaa ttcggcctgg cggcgacgca ggtgctgcaa ctggtggaga
    16621 ccctgcgtga cgctgggcgt ctggacagtc tgcaactgtt gcacttccac ctgggatcgc
    16681 agatggcgaa cattcgcgat atcgcgaccg gcgtgcgcga gtccgcgcgt ttctatgttg
    16741 agctgcataa gctgggcgtt aatatccagt gcttcgacgt gggcggcggt ctgggcgtgg
    16801 attatgaagg tacccgctcg cagtccgact gttcggtgaa ctatggcctg aacgaatatg
    16861 ccaataacat catctgggcg attggcgatg cctgcgaaga gcatggttta ccgcatccga
    16921 cggtgattac cgagtctggg cgcgccgtca ctgcgcacca tacggtactg gtctctaaca
    16981 ttatcggcgt ggagcgtaac gaatacacgg atccgaccgc ccctgctgaa gatgcgccgc
    17041 gcgcgctgca aaatctgtgg gaaacctggc aggagatgca taagcctggc acccgccgct
    17101 cgctgcgtga atggctgcat gatagccaaa tggatctgca cgatattcat atcggctact
    17161 cttccggcgc gtttagtttg caggagcgcg cctgggcgga gcaactttat ctcagcatgt
    17221 gccatgaagt gcagaagcaa ctggacccgc aaaaccgtgc gcatcgcccg attatcgacg
    17281 aactgcaaga gcggatggcg gacaaaatgt acgtcaactt ctcgctgttc cagtcgatgc
    17341 cggacgcgtg gggaatcgat cagctctttc cggtgctgcc gctggaaggg ttagatcagg
    17401 taccggaacg tcgtgccgtg ctgctggata ttacctgtga ttccgatggc gctatcgacc
    17461 actatatcga tggcgacggt atcgccacga cgatgccgat gccggaatac gatccagaga
    17521 atccgccgat gctcggcttc tttatggtcg gcgcctatca ggagatcctc ggtaacatgc
    17581 acaacctgtt tggcgatact gaagcggttg acgtgtttgt cttcccggat ggtagtgtcg
    17641 aggttgagtt gtcggacgaa ggcgataccg ttgcggatat gctgcaatat gtgcaactgg
    17701 atccgaaaac gctattaacg catttccgcg accaggtaaa acagacggat ctggacgatg
    17761 cgttgcagca gcagttcctt gaggaatttg aagcgggact gtacggttat acttatcttg
    17821 aagatgagta gccgttgatg cccggcggcg ctgcgcttac cgggcctacg aatgcaggct
    17881 ggataaggta aagccgccac ccggcagaat gctatactca cttgaacccg tatgaattaa
    17941 cggcgataat tcgctgcaat agcgatttac aaatcaatcc cttcctcgtc gggtttaacg
    18001 acgcggaggg gatttttttc atctgtttta atgcaacgac tctaaaagag gtcaggacat
    18061 gagcacttta ggtcatcagt acgataactc actggtttct aatgcgtttg gttttttacg
    18121 tctgccaatg aacttccagc cgtatgacag cgatgccgac tgggtgatca ctggcgtacc
    18181 gtttgatatg gcaacgtccg gtcgcgctgg cggccgtcat ggcccggcgg cgatccgtca
    18241 ggtgtcgacc aacctcgcct gggaacatca ccgtttcccg tggaattttg acatgcgcga
    18301 gcgcctgaac gtcgtggact gcggcgatct ggtgtatgcg tttggcgatg cccgtgaaat
    18361 gagcgaaaaa ttacaggcgc acgctgaaaa actgctgtct gcaggcaagc gtatgctctc
    18421 tttcggcggc gaccacttcg tcacgctgcc gctgctgcgc gcccacgcga aacattttgg
    18481 caaaatggcg ctggtacatt ttgacgcgca taccgatacc tacgctaacg gctgcgaatt
    18541 cgatcacggc acgatgttct acaccgcgcc gaaagaaggc ctgatcgatc cgcatcattc
    18601 ggtacagatc ggtattcgca ctgagtttga caaagacaat ggctttaccg tgctggatgc
    18661 ctgccaggtc aacgatcgcg gcgtggatga tattctcgct caggtgaaac agatcgtcgg
    18721 cgatatgccg gtctatctga cctttgatat cgactgtctg gacccggcgt ttgcgcctgg
    18781 caccggtacg ccggtgatcg gtggtttgac ctccgatcgc gccattaagc tggtacgtgg
    18841 tctgaaagat ctgaacattg tcggtatgga tgtagtggaa gtcgcgccgg cttacgatca
    18901 gtcggagatc accgctctgg cggccgcgac gctggcatta gaaatgctct atatccaggc
    18961 ggcgaagaag ggcgagtaag ttgttttgcc ggatggcact gcgcttatcc ggcctacgct
    19021 taccgggcct gtgtaggccg gataaggcgt tcacgccgcc atccggcact gttcggggat
    19081 tatttgatcc cgtccgcgct catacgatcg cgcacatgct gtgcgcgtgc ggcggacgcc
    19141 gggtgatcgt cgaacattga gctttgacga cccgcttcca gttttgccag tttctcaaag
    19201 ctggtggcga gtcctgccgg actgataccg cgtttgcgca acagatcgta agaataatca
    19261 tccgcttcgg actcctgacg ctgagagaac tgcgagttca ccagtttttc gccaagatcg
    19321 ccaagctgtg attgcgacag gctgccgaca acgcctcctg ccgatgccgc cgcaacgcgc
    19381 acggcgttag tgcccagcgc gacctgcatc cctttcttta catgacccag agcgacatgg
    19441 cccatttcat gaccgatcac ggcttcaact tcgttgtcgg tcatcatatc catcagtccg
    19501 ctgtagacgc ggatacaacc gttcgccatg gcaaacgcgt tgacgtcttt cgtctcgtaa
    19561 actttatagt tcaccggctg gccgttaatg ttatccccca gcgcggcggc aatttttgcc
    19621 agtcgtttag tgtattcgct gctcgccggc gcgattttcg ctttgctgtc gagctcttga
    19681 caggattgat cgctcaacgc ttttacctgc gcatcgctta acgtataggc ctgaaaagct
    19741 tcagcgcccg aagaaagcag tccattagag tccatattct ggcaaccggt cagcaccgtc
    19801 gccatgccca aagcaagcag taaagcgcga attttcattt ttctcttcca tacgaattaa
    19861 tattattttg aaatgcgccc gttgcagatg aattagcgcc tgggttaagt ataaagaaaa
    19921 gcgtggcagg caagttagct aattgcgcaa catgcgagca cgatccggag atttctgaag
    19981 cggtaaaagg atgttccatg tacatgacgc gcggcttggg gtaaattgtt ggcaaatttt
    20041 ccggcgtagc ccaaaacgcg ctgtcgtcaa gtcgttacgg gcatggcctt tcaacatccg
    20101 atctggagtc aaaatgtcct cacgtaaaga gcttgccaat gctattcgtg cgctgagcat
    20161 ggacgcagta cagaaagcca aatccggtca cccgggtgcc ccgatgggta tggctgacat
    20221 tgccgaagtc ctgtggcgtg atttcctgaa ccacaacccg accaacccgt cttgggccga
    20281 ccgcgaccgc ttcgtgctgt ccaatggcca cggctcaatg ctgatttaca gcctgctgca
    20341 cctcaccggt tatgacctgc cgatgtccga actgcagaat ttccgtcagc tacattcaaa
    20401 aacccctggt cacccggaag tgggctacac cgctggcgtt gaaaccacta ccggcccgct
    20461 ggggcagggt attgccaacg ccgtcgggat ggcgattgcc gagaaaactc tggcggcgca
    20521 gtttaaccgt cctggccacg acatcgttga ccacttcacc tacgtcttta tgggcgacgg
    20581 ctgcatgatg gaaggcattt ctcacgaagt gtgctctctg gctggtactc tgaaactggg
    20641 caaactgatc gcgttctatg atgacaacgg tatctctatc gatggtcatg ttgaaggctg
    20701 gttcaccgat gacaccgcga aacgttttga agcctacggc tggcacgtta tccgtggcat
    20761 tgacggtcac gatgccgacg ccattaaacg tgccacggaa gaagctcgcg ccgtgactga
    20821 caaaccgtcc ctgctgatgt gcaaaaccat catcggcttc ggttcgccga acaaacaggg
    20881 tacccacgat tcccacggcg cgccgctggg cgacgcggaa atcgcgctga cccgcgaaca
    20941 gttgggctgg aaatacgcgc cgttcgaaat cccgtctgaa atctacgccc agtgggatgc
    21001 gaaagaagcc ggccaggcga aagagtctgc atggaatgag aaattcgcgg cttatgagaa
    21061 agccttcccg caggaagctg ctgaattcac tcgtcgtatg aaaggcgaca tgccggctga
    21121 cttcaatgcg aaagcgaatg agttcatcgc taaactgcag gcgaatccat ccaaaatcgc
    21181 cagccgtaaa gcgtcccaga atgccatcga agccttcggt ccgctgttgc cggaattcct
    21241 cggcggctcc gctgacctgg caccgtctaa cctgaccctg tggtccggtt cgaaagcgat
    21301 taacgaagat gccgcaggta actacattca ttacggtgtg cgcgaattcg gtatgaccgc
    21361 tatcgccaac ggtatcgccc tgcacggcgg tttcctgccg tacacctcca ccttcctgat
    21421 gttcgtcgaa tatgcccgta acgcagtgcg tatggcagcg ttgatgaaac agcgtcaggt
    21481 gatggtctat acccacgact ccatcggtct gggcgaagat ggcccgacgc accagccggt
    21541 cgagcaggtg gcaagcctgc gcgtaacgcc gaacatgtcc acatggcgtc cgtgcgacca
    21601 ggtggaatcc gcggtggcgt ggaaatatgg cgtagagcgt caggatggcc caaccgcgct
    21661 gattctgtcc cgtcagaacc tggcgcagca ggagcgtact gaagagcaac tggcgaatat
    21721 cgcccgcggt ggttacgtac tgaaagattg tgcgggccag ccgcagatta tcttcattgc
    21781 gaccggttct gaggttgagc tggcggttgc cgcctacgaa aaactgactg ccgaaggcgt
    21841 gaaggcgcgc gtggtttcca tgccgtccac cgacgcgttc gacaagcagg atgcggccta
    21901 ccgtgaatcc gtgctgccga aagcggtctc tgcgcgtgtg gcgattgaag cgggtatcgc
    21961 tgactactgg ttcaaatacg tcggcctgaa cggcgctatt gtcgggatga ccaccttcgg
    22021 tgaatccgcc ccggcagagc tgctgtttga agagtttggc ttcacggtgg acaacgtgat
    22081 cgccaaagcg aaagcgctgc tgtaatcctt aatacggcat aaaacgggtc gcttcggcga
    22141 ccc
//
LOCUS       DAJVKX010000070        22093 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000070 DAJVKX010000000
VERSION     DAJVKX010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22093
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.070"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(193..306)
                     /locus_tag="OPY25_002718"
     CDS             complement(193..306)
                     /locus_tag="OPY25_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HCS0928300.1"
                     /translation="MRRLFHFLMNNIREHFMLYVILWSLLAVMDIVYLLFF"
     gene            complement(347..1465)
                     /gene="solA"
                     /locus_tag="OPY25_002719"
     CDS             complement(347..1465)
                     /gene="solA"
                     /locus_tag="OPY25_002719"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HCS0928301.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLKVLMTDAHMPPYQQGSHH
                     GDTRLIRHAYGEGEKYVPLVLRAQTLWDELSTHNEEPIFVRSGVVNLGPADSAFLANV
                     ARSAQQWQLNVERLDATALMTRWPEIRVPDNYIGLFEADSGFLRSELAITTWLRLARE
                     AGCAQLFNSPVSHIHHDDNGVTIETSEGCYHASKALISAGTWVKTLVPELPVQPVRKV
                     FAWFKADGRYSTKNRFPAFTGEMPNGDHYYGFPAENDELKIGKHNGGQRIQAPEERKP
                     FAAVASDGAEAFPFLRNVLPGIGGCLHGAACTYDNSPDEDFIIDTLPGHENTLVITGL
                     SGHGFKFAPVLGEIAADFALGKTPSFDLTPFRLSRFSQ"
     gene            complement(1578..1832)
                     /gene="bssS"
                     /locus_tag="OPY25_002720"
     CDS             complement(1578..1832)
                     /gene="bssS"
                     /locus_tag="OPY25_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460132.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HCS0928302.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNRPEPEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDYQENEYRHH"
     gene            complement(2122..2367)
                     /gene="dinI"
                     /locus_tag="OPY25_002721"
     CDS             complement(2122..2367)
                     /gene="dinI"
                     /locus_tag="OPY25_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HCS0928303.1"
                     /translation="MRIEVTIAKTSPLPAGAIGALAGELSRRISHHFPENLGNVTVRY
                     ATANNLSVIGASKEDKERISEILQETWESADDWFINE"
     gene            complement(2441..3487)
                     /gene="pyrC"
                     /locus_tag="OPY25_002722"
     CDS             complement(2441..3487)
                     /gene="pyrC"
                     /locus_tag="OPY25_002722"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCS0928304.1"
                     /translation="MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAA
                     KLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDT
                     VMEPLRQRLTALKVVFEHITTKDAAQYVRDGSYNLAATITPQHLMFNRNDMLVGGIRP
                     HLYCLPILKRNIHQQALRDLVASGFTRAFLGTDSAPHSRHRKETRCGCAGCFNAPSAL
                     GSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLV
                     PFLAGETVRWSVKK"
     gene            complement(3591..4190)
                     /locus_tag="OPY25_002723"
     CDS             complement(3591..4190)
                     /locus_tag="OPY25_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0928305.1"
                     /translation="MSRLGHRQHAKERHEKVFFAAALVVSGLLVGCNQLTQYTISEQE
                     INQALEKRNNFSKDIGLPGIADAHIVLTNLASQIGREEPNKVTLTGDARLDMNSLFGS
                     QKATMKLKLKALPVFDKEKGAIYLQEMEVVDATVTPEKMQSVLQTLLPYLNQSLRSYF
                     NQRPAYVLREDSSKGEALAKKLAKGIEVKPGEIVIPFTN"
     gene            complement(4275..4922)
                     /gene="grxB"
                     /locus_tag="OPY25_002724"
     CDS             complement(4275..4922)
                     /gene="grxB"
                     /locus_tag="OPY25_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HCS0928306.1"
                     /translation="MKLYIYDHCPFCVKARMIFGLKNIPVELNVLQNDDEATPTRMIG
                     QKMVPILQKDDSRYLPESMDIVHYVDNLDGKPLLTGKRNPAIEEWLRKVNGYVNQLLL
                     PRFAKSAFDEFSTPAARQYFIRKKEASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQ
                     PNAVNGELSEDDIHLFPLLRNLTLVAGIHWPTKVADYRDNMAKQTQINLLSSMAI"
     gene            complement(4986..6194)
                     /gene="mdtH"
                     /locus_tag="OPY25_002725"
     CDS             complement(4986..6194)
                     /gene="mdtH"
                     /locus_tag="OPY25_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HCS0928307.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAILFILCALFNAWLLPAWKLSTARTPVREGMRRVMSNKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHR
                     LMAGLLVMSLSMLPIGMVGNLQQLFTLICAFYIGSVIAEPARETLSASPADARARGSY
                     MGFSRLGLAIGGAISYIGGGWLFDMGKALAQPELPWMMLGIIGFITFLALGWQFSHKR
                     TPRRMLEPGA"
     gene            6431..7015
                     /gene="rimJ"
                     /locus_tag="OPY25_002726"
     CDS             6431..7015
                     /gene="rimJ"
                     /locus_tag="OPY25_002726"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HCS0928308.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHERDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMIGEFHKQGSAFYFALLDPEEKEIIGVANFSNVVRGSF
                     HACYLGYSIAQEWQGQGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGALLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPLWTPGR"
     gene            7051..7698
                     /locus_tag="OPY25_002727"
     CDS             7051..7698
                     /locus_tag="OPY25_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HCS0928309.1"
                     /translation="MKYELTATEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLTEQEVQEQLDNLVKRHFLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     VTTLLLRGAQTPGELRSRASRMHEFSDMAEVESTLERLASREDGPYVVRLAREPGKRE
                     SRYMHLFCGDVDELSLQTSAPESASGDLQSRVEALESEVAELKQRLDSLLAHLGE"
     gene            7700..8623
                     /locus_tag="OPY25_002728"
     CDS             7700..8623
                     /locus_tag="OPY25_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCS0928310.1"
                     /translation="MRTLRIGIVVLGGIAQKAWLPVLTNTAGWTLQGAWSPSRDKALR
                     ICESWRIPYVDSLANLASGCDAVFVHSSTASHYAVVSELLNAGVHVCVDKPLAENLRD
                     AERLVALAAQKKLTLMVGFNRRFAPLYRELKTRLGTAASLRMDKHRTDSIGPHDLRFT
                     LLDDYLHVVDTVLWLAGGEARLASGTLLTSESGEMCYAEHHFSADKLQITTSMHRRAG
                     SQRESVQAVTDGGLYDVTDMREWREERGQGILIKPIPGWQTTLEQRGFVGCARHFIDC
                     VQNQTVPETAGEQAILAQRVVEALWRDAISE"
     gene            8927..10462
                     /gene="murJ"
                     /locus_tag="OPY25_002729"
     CDS             8927..10462
                     /gene="murJ"
                     /locus_tag="OPY25_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HCS0928311.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEEATRIFVAYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTTQLLRITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTFLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPYLKKIGMLVLPR
                     INFHDTGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWLYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYCRLMDWGLRLCFLLALPSAVALGILAKPLTV
                     SLFQYGKFTAFDAAMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     MTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQNIFTPQPGWMWFLMRLII
                     SVLVMAAVLFGVLHIMPEWSQGSMLWRLLRLMAVVIAGIAAYFAALAVLGFKVKEFVR
                     RTA"
     gene            complement(10544..10966)
                     /gene="flgN"
                     /locus_tag="OPY25_002730"
     CDS             complement(10544..10966)
                     /gene="flgN"
                     /locus_tag="OPY25_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HCS0928312.1"
                     /translation="MTRLSEILDQMTTVLNDLKTVMDAEQQQLSVGQINGSQLQRITE
                     EKSSLLATLDYLEQQRRLEQNAQRSANDDIAERWQAITEKTQHLRDLNQHNGWLLEGQ
                     IERNQQALEVLKPHQEPTLYGADGQTSVSHRGGKKISI"
     gene            complement(10971..11264)
                     /gene="flgM"
                     /locus_tag="OPY25_002731"
     CDS             complement(10971..11264)
                     /gene="flgM"
                     /locus_tag="OPY25_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HCS0928313.1"
                     /translation="MSIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLS
                     DAQAKLMQPGVSDINMERVEALKTAIRNGELKMDTGKIADSLIREAQSYLQNK"
     gene            complement(11356..12015)
                     /gene="flgA"
                     /locus_tag="OPY25_002732"
     CDS             complement(11356..12015)
                     /gene="flgA"
                     /locus_tag="OPY25_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HCS0928314.1"
                     /translation="MQTLKRGFAVAALLFSPLTMAQDINAQLTTWFSQRLAGFSDEVV
                     VTLRSPPNLLPSCEQPAFSMTGSAKLWGNVNVVARCANEKRYLQVNVQATGNYVAVAA
                     PVARGGKLTPANVTLKRGRLDQLPPRTVLDIRQIQDAVSLRDLAPGQPVQLTMIRQAW
                     RVKAGQRVQVIANGEGFSVNAEGQAMNNAAVAQNARVRMTSGQIVSGTVDSDGNILIN
                     L"
     gene            12172..12588
                     /gene="flgB"
                     /locus_tag="OPY25_002733"
     CDS             12172..12588
                     /gene="flgB"
                     /locus_tag="OPY25_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HCS0928315.1"
                     /translation="MLDRLDAALRFQQEALNLRAQRQEILAANIANADTPGYQARDID
                     FASELKKVMVRGREETGGVALSLTSSRHIPAQAVSSPAVDLLYRVPDQPSLDGNTVDM
                     DRERTQFADNSLKYQMGLTVLGSQLKGMMNVLQGGN"
     gene            12592..12996
                     /gene="flgC"
                     /locus_tag="OPY25_002734"
     CDS             12592..12996
                     /gene="flgC"
                     /locus_tag="OPY25_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HCS0928316.1"
                     /translation="MALLNIFDIAGSALAAQSKRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVDAAPGQATGGVKVASVIESQAPEKLVYEPGNPLADANGYVKMPNVDVVGEM
                     VNTMSASRSYQANIEVLNTVKSMMLKTLTLGQ"
     gene            13008..13706
                     /gene="flgD"
                     /locus_tag="OPY25_002735"
     CDS             13008..13706
                     /gene="flgD"
                     /locus_tag="OPY25_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HCS0928317.1"
                     /translation="MSIAVNMNDPTNTGVKTTTGSGSMTGSNAADLQSSFLTLLVAQL
                     KNQDPTNPLQNNELTTQLAQISTVSGIEKLNTTLGAISGQIDNSQSLQATTLIGHGVM
                     VPGTTILAGKGAEEGAVTSTTPFGVELQQPADKVTATITDKDGRVVRTLEIGELRAGV
                     HTFTWDGKQTDGTTVPNGSYNIAITASNGGTQLVAQPLQFALVQGVTKGSNGNLLDLG
                     TYGTTTLDEVRQII"
     gene            13733..14944
                     /gene="flgE"
                     /locus_tag="OPY25_002736"
     CDS             13733..14944
                     /gene="flgE"
                     /locus_tag="OPY25_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HCS0928318.1"
                     /translation="MSFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGMQLTGYPATGTPPTIQQGANPAPITIPNTLMAAKSTTTASMQINLNS
                     TDPVPSKTPFSVSDADSYNKKGTVTVYDSQGNAHDMNVYFVKTKDNEWAVYTHDSSDP
                     AATAPTTASTTLKFNENGILESGGTVNITTGTINGATAATFSLSFLNSMQQNTGANNI
                     VATNQNGYKPGDLVSYQINNDGTVVGNYSNEQEQVLGQIVLANFANNEGLASQGDNVW
                     AATQASGVALLGTAGSGNFGKLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQ
                     DQILNTLVNLR"
     gene            14965..15720
                     /locus_tag="OPY25_002737"
     CDS             14965..15720
                     /locus_tag="OPY25_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgF"
                     /protein_id="HCS0928319.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVDGLSLATRTLVTASTPGADMTQGQLDYTSRPLDVALQQDGWLVVQAADGAEGYTRN
                     GNIQVGPTGQLTIQGHPVIGEGGPITVPEGSEITIAADGTISALNPGDPPNTVAPVGR
                     LKLVKAEGNEVQRSDDGLFRLTAEAQAERGAVLAADPSIRIMSGVLEGSNVKPVEAMT
                     DMIANARRFEMQMKVITSVDENEGRANQLLSMS"
     gene            15734..16516
                     /gene="flgG"
                     /locus_tag="OPY25_002738"
     CDS             15734..16516
                     /gene="flgG"
                     /locus_tag="OPY25_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HCS0928320.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGTSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYIETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            16571..17269
                     /gene="flgH"
                     /locus_tag="OPY25_002739"
     CDS             16571..17269
                     /gene="flgH"
                     /locus_tag="OPY25_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HCS0928321.1"
                     /translation="MQKYALHAYPVMALMVATLTGCAWIPAKPLVQGATTAQPIPGPV
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     SFGFDTVPRYLQGLFGNSRADMEASGGNSFNGKGGANASNTFSGTLTVTVDQVLANGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNSVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            17281..18378
                     /locus_tag="OPY25_002740"
     CDS             17281..18378
                     /locus_tag="OPY25_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HCS0928322.1"
                     /translation="MFKALAGIVLALVATLAHAERIRDLTSVQGVRENSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASYPPFARQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAIIERELPTQFGAGNTINLQLNDEDFTMAQQITDAINRARGYGSATALDA
                     RTVQVRVPSGNSSQVRFLADIQNMEVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQLNVNQPNTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSANLNSVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            18378..19328
                     /gene="flgJ"
                     /locus_tag="OPY25_002741"
     CDS             18378..19328
                     /gene="flgJ"
                     /locus_tag="OPY25_002741"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HCS0928323.1"
                     /translation="MIGDGKLLASAAWDAQSLNELKAKAGQDPAANIRPVARQVEGMF
                     VQMMLKSMREALPKDGLFSSDQTRLYTSMYDQQIAQQMTAGKGLGLADMMVKQMTGGQ
                     TMPADDAPQVPLKFSLETVNSYQNQALTQLVRKAIPKTPDSSDAPLSGDSKDFLARLS
                     LPARLASEQSGVPHHLILAQAALESGWGQRQILRENGEPSYNVFGVKATASWKGPVTE
                     ITTTEYENGEAKKVKAKFRVYSSYLEALSDYVALLTRNPRYAAVTTAATAEQGAVALQ
                     NAGYATDPNYARKLASMIQQLKAMSEKVSKTYSANLDNLF"
     gene            19393..21054
                     /gene="flgK"
                     /locus_tag="OPY25_002742"
     CDS             19393..21054
                     /gene="flgK"
                     /locus_tag="OPY25_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HCS0928324.1"
                     /translation="MSSLINHAMSGLNAAQAALNTVSNNINNYNVAGYTRQTTILAQA
                     NSTLGAGGWIGNGVYVSGVQREYDAFITNQLRGAQNQSSGLTTRYEQMSKIDNLLADK
                     SSSLSGSLQSFFTSLQTLVSNAEDPAARQALIGKAEGLVNQFKTTDQYLRDQDKQVNI
                     AIGSSVAQINNYAKQIANLNDQISRMTGVGAGASPNDLLDQRDQLVSELNKIVGVEVS
                     VQDGGTYNLTMANGYTLVQGSTARQLAAVPSSADPTRTTVAYVDEAAGNIEIPEKLLN
                     TGSLGGLLTFRSQDLDQTRNTLGQLALAFADAFNAQHTKGYDADGNKGKDFFSIGSPV
                     VYSNSNNADKTVSLTAKVVDSTKVQATDYKIVFDGTDWQVTRTADNTTFTATKDADGK
                     LEIDGLKVTVGTGAQKNDSFLLKPVSNAIVDMNVKVTNEAEIAMASESKLDPDVDTGD
                     SDNRNGQALLDLQNSNVVGGNKTFNDAYATLVSDVGNKTSTLKTSSTTQANVVKQLYK
                     QQQSVSGVNLDEEYGNLQRYQQYYLANAQVLQTANALFDALLNIR"
     gene            21069..22022
                     /gene="flgL"
                     /locus_tag="OPY25_002743"
     CDS             21069..22022
                     /gene="flgL"
                     /locus_tag="OPY25_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HCS0928325.1"
                     /translation="MRISTQMMYEQNMSGITNSQAEWMKLGEQMSTGKRVTNPSDDPI
                     AASQAVVLFQAQAQNSQYALARTFATQKVSLEESVLSQVTTAIQTAQEKIVYAGNGTL
                     SDDDRASLATDLQGIRDQLMNLANSTDGNGRYIFAGYKTEAAPFDQATGGYHGGEKSV
                     TQQVDSARTMVIGHTGAQIFNSITSNAVPEPDGSDSEKNLFVMLDTAIAALKTPVEGN
                     DVEKEKAAAAIDKTNRGLKNSLNNVLTVRAELGTQLSELSTLDSLGSDRALGQKLQMS
                     NLVDVDWNSVISSYVMQQAALQASYKTFTDMQGMSLFQLNR"
BASE COUNT         5296 a         5684 c         6172 g         4941 t
ORIGIN      
        1 aagaatttga atgatattta tttttatttc aataattttg atgttgtttg cgattcagct
       61 tcagaagttt cgagatattt cactcctgta accgcacaac ggcaggagtt ggcattattg
      121 ccgtgcttca acattatgaa ataaaaagtg aggaactttc aggaagtgtt agttaacgtc
      181 aatgaaaagc aatcagaaga aaaggagata aacaatatcc atcaccgcca gcagcgacca
      241 aagaataacg taaagcatga aatgttcgcg aatattattc atcagaaaat gaaagagacg
      301 acgcatagct taccttaata aacagcccct ttacggggcc gacaaattat tggctaaaac
      361 gggaaagccg gaacggcgtc agatcaaagg agggcgtttt tcccaacgca aaatccgcag
      421 cgatttctcc taacaccggg gcgaatttaa aaccatgtcc gctgagtcca gtgatgacaa
      481 gcgtattctc atggccaggc agcgtatcga taataaaatc ctcgtccggc gaattatcat
      541 aggtacatgc cgccccatgt aaacaaccgc cgatacccgg cagtacgtta cgcaggaaag
      601 gaaatgcttc cgcgccatcg ctggcaacgg cggcaaaggg cttgcgctct tccggtgcct
      661 gtattcgctg cccgccattg tgtttgccga tttttaactc gtcgttctcc gccgggaaac
      721 cgtaatagtg atcgccgttg ggcatttcgc cggtaaaggc cggaaagcgg tttttagtgc
      781 tgtaacgtcc atccgcctta aaccaggcaa aaactttacg tacgggctga acgggcagct
      841 ccggtaccag cgttttgacc caggtgcccg cgctaatcag cgctttgctg gcgtggtagc
      901 agccttcact cgtctctatc gtcacaccgt tatcatcatg gtgaatatgg cttaccgggc
      961 tgttgaatag ctgtgcgcag cctgcctctc gggccagacg aagccatgtg gtaatggcta
     1021 attcgctgcg caggaaaccg gagtcagctt caaacagccc gatataatta tcgggcacgc
     1081 gaatttccgg ccagcgcgtc atgagggccg tcgcgtccag gcgctcgacg ttcaattgcc
     1141 actgttgcgc gcttcgtgcg acgttggcta agaaagcgga atcggccggg ccgaggttga
     1201 cgacgccgga gcggacaaaa ataggctctt cattgtgtgt ggagagctca tcccaaagcg
     1261 tctgggcgcg aagcaccagc gggacatatt tttcgccttc accataagcg tggcggataa
     1321 gacgggtatc gccgtggtgg ctgccctgtt gataaggcgg catatgcgca tcggtcatca
     1381 ggacctttag cccggcgcgg gtggcgtaat aaccagcggc ggcgccaacc gaaccgctgc
     1441 cgataataat aaggtcgtat ttcatcagct tctctctgct atcgcgatga tttcaaggta
     1501 aataactgcg ctgagatata caagccagaa ataagtgagg caccttacgg tgcctgagag
     1561 agggggagcg cgtcacgcta atggtgacga tactcgtttt cctggtaatc gcctgattct
     1621 attttggcga tgccggcttc taatattgaa ataaattgcc tggctacatc tgtcgttaac
     1681 cagagcgttt gaccaacttc agtcccttcc ggttccggac gatttggggt ctggtagtgt
     1741 aaacgcagca tcagcgcatc atagctatcg acggtgctga tgtcccatcc tacaagcgga
     1801 tgggtctgaa tgacttcatt attcttttcc atcatgcccc cctggtacgt gttataagac
     1861 aacggttctc gaggttcaat gcgtgttttt cttctgaagc aacttcagta taccaattaa
     1921 taaggctatt cactgcgttt ttaaagagac cggaggataa atttctcttt ttaagaatta
     1981 tatgaacaat aaagcggcag ttcattcata tttttttagg atgttgtgca attattttga
     2041 cggtcaggcg aaatattcat cagttgcgca aataaaaaag ccggggcgac ccggcaaaca
     2101 tacatcactg catatcattt tttattcatt gatgaaccag tcatcagcgc tctcccaggt
     2161 ctcctggaga atctcgctaa tgcgttcttt atcctctttt gacgcgccaa tgacggacaa
     2221 gttgttggcg gtagcgtaac gcacggtgac gttacccaaa ttctcaggaa aatgatggct
     2281 aatacggcgg gagagttcgc ccgccagcgc accaatcgca ccggcaggca gaggtgacgt
     2341 tttggctata gtgacttcaa tacgcataat ggccccctgt tgaatatact ggatatatat
     2401 acagttaaat ccaatatata gcaacaggta agcgcatttt ttattttttt actgaccagc
     2461 gtactgtttc acccgctaaa aaaggcacca gcgaatcatc agccagcgcg atattttccg
     2521 gtatctgttg ttcatcgcga accagttcca cccaccccgt attcaccggc aggccataga
     2581 attgcgggcc attcagtgaa cagaacgctt caaagtgcgc cagcgcgttc atttcctcaa
     2641 acacggcggc ataactgcca agagcggagg gggcgttgaa acaaccggcg cagccgcaac
     2701 gggtctcttt acgatgacgt gaatgcggcg ctgaatccgt ccccaggaag gcgcgcgtaa
     2761 aaccactggc gaccaggtcg cgtaacgcct gctggtgaat attgcgtttc agaatcggca
     2821 gacagtacag gtgaggacga atgccgccaa ccagcatatc attacggtta aacattaaat
     2881 gttgaggcgt aatggtcgcc gccaggttgt agctgccgtc acgtacatac tgcgcggcat
     2941 ctttggttgt gatgtgttca aagaccactt taagcgcggt cagacgctgg cgtagcggtt
     3001 ccattacggt gtcgataaaa cgcgcttcgc gatcgaagat atcaacatcc gcatgggtca
     3061 cctcaccgtg gaccagcaat ggcattccga gtttttccat ccgctccagt accggcatga
     3121 tagcgtcgac tgacgttacg ccatgactgg agttagtggt ggcattggcc gggtaaagct
     3181 tggccgcagt aaacacgcct tcatggaaac cacgctccag ttcatcggca tcgagcgaat
     3241 ccgttaaata gcaggtcatt aacggcgtga aatcatgccc ggcgggcacc gcatcgagaa
     3301 tacgctggcg gtaggcgatc gctgcatcaa cggtcgtaat gggggacgcc aggttcggca
     3361 tcacgatagc gcgaccataa atttcgctgg tatagggtac gaccgttttt aacatgtcgc
     3421 catcgcgaag gtgaacgtgc cagtcgtccg ggcggcggat ctttaaaacc tgggatggtg
     3481 cagtcattaa taagctccgg ctgaggaata gtctttttgc cggaaacaaa ggataagcgg
     3541 aaacgttttc gtttgcacgt aaaaaaaggg cgcgagcgcg ccctccgaaa tcaattggtg
     3601 aaaggaataa cgatttcacc aggtttaact tcaatgcctt tcgcgagttt cttcgctaac
     3661 gcttcgcctt tactactgtc ctcacgcaac acgtaagcgg gccgctggtt aaagtagcta
     3721 cgtaaagact gatttaaata gggcaggagc gtttgtagca ctgattgcat tttctccggc
     3781 gtcacggtgg cgtctactac ttccatctcc tgaagataga tggcgccttt ttctttatca
     3841 aagaccggca gggcttttag cttgagtttc atcgtcgctt tttgactgcc aaacagggaa
     3901 ttcatatcca gcctggcatc gccagtaagg gtgactttat taggctcttc ccgaccaatc
     3961 tggctggcaa ggttagtcaa tacgatatgc gcgtcggcaa tgccaggcag accaatatct
     4021 tttgagaaat tattccgttt ttcaagcgct tgattgattt cttgttcgct aatggtgtat
     4081 tgcgtaagtt gattacaacc cactaacagg ccgctaacta ccagcgcagc ggcaaaaaaa
     4141 actttttcat ggcgttcctt agcatgttgc ctgtgcccta atcttgacac aaagcagcat
     4201 gtcgcgccag cggacatggc gccactaaaa aaagctgaaa aaggcggcaa gaaagggttg
     4261 ccgcctggcg ggcgttagat agccattgag gagagtaaat taatttgcgt ctgcttagcc
     4321 atattatcgc gatagtccgc gacttttgtc ggccagtgaa taccggcgac cagcgtcaga
     4381 ttacgcagaa gcggaaacag atgaatatca tcttccgata attcgccgtt aacggcgtta
     4441 ggctgtacga tgagtttatc cagcaaacgt aaatcatcgc cgatcttttt aatcagtccg
     4501 gcagagtgcg caagatggtt gtcaaaactg ccagatgagg cctctttttt gcggataaaa
     4561 tactggcgcg ccgcaggggt agaaaattca tcgaaagcgg attttgcaaa tcgcggcagc
     4621 agtagctgat taacgtaacc gttaactttg cgcaaccact cttcaatggc tggattacgt
     4681 ttcccggtta acagcggttt gccgtcgagg ttgtcgacat aatgtacaat atccatactt
     4741 tcaggaaggt agcgactatc atctttttgc aggatgggca ccatcttttg accaatcatc
     4801 cgggtgggcg tcgcctcgtc gtcattttgt aacacgttaa gttcaacggg gatgttcttc
     4861 aggccgaaaa tcatgcgggc tttaacgcag aaagggcaat gatcgtaaat ataaagcttc
     4921 acgtttctcc tccatttgac tgtcggttcc tgaccagtat ggaggagata gcgacaggta
     4981 tcaaatcagg cgccgggttc cagcatccgg cgcggcgtgc gcttatgact aaattgccag
     5041 cctaaagcca aaaaggtgat aaagccgata ataccgagca tcatccacgg tagttcaggc
     5101 tgcgcaagcg ctttacccat atcaaacaac cagccgccgc cgatataact aatcgcgccg
     5161 ccaatggcta atcccagacg gctaaagccc atatagcttc cccgcgccct cgcgtccgcg
     5221 ggcgacgcgc tgagcgtttc gcgcgccggt tcggcgataa ccgagccgat gtagaaagcg
     5281 caaataagcg taaaaagctg ctgtaaattg cccaccatcc cgatggggag catgctcagc
     5341 gacatgacga gcaaaccggc catcagccga tgctccagcc gaaaacgctt ttcgctccag
     5401 cgggcaatcg ggtagagcaa cgtcagcgag agacacgcct caatagcgta catccatttc
     5461 acggcagcag gcgaaccggc gatatcgttt accataatcg gcagcattaa catgacctgt
     5521 accgccagca tatagtagcc cgccagcgtc agcacgtagg tgacaaacct tttattgctc
     5581 atgacgcggc gcattccttc acgcaccggc gttctggccg ttgatagctt ccaggccgga
     5641 agcagccatg cgttgaaaag ggcgcataat atgaacaaaa tagcgcccgt cgcgcagacc
     5701 aggcgaaaat cgtattgtag caaccagctt cccagcagcg cgccaatcac cgcgcccgcg
     5761 ctgtcctgca tcatcaacag agagaagaag cggccccgtt gctccggacg aattaatttg
     5821 accaccagcg ctgaacgcgg cgggtcgaaa agcgtaccgc cgagaccgga aagaaagcag
     5881 gaaaaccaca agagccaggg ctcatgcgcg atacccatgg tggcaaagcc tgcggcgcgc
     5941 atcagcatac cggtgacaat catcggtttc gcgccaaagc gatcggcgat ggcgccgcca
     6001 aaaatgccca gaccttgttg aataaactga cgcaggccga gcgcgatccc taccattacg
     6061 gcagcccacc ccatttgatc gacaaagcga atagagatga gcgggaagac gacgaaaaaa
     6121 cccagcacca ctaacatgtt atcgatgaga agaaaatatt tacccaggtt cctcgcctgc
     6181 gagacgcgcg acatttcccc tcccgggaaa taaaagatga gcgtcttcta ttctgcggcg
     6241 gcgtttcgtt ttttcctacc gttagcggga caatattttt ttatcaaaag tcctttttaa
     6301 tcgagagttt tcatcaaaat gtggcagcaa ttcaaaaaat gacgatttgc gcttttcaca
     6361 gggcctggtt gcgcaggtat agtaatgtta ctggcgtgct gaagacgtta caggaaggag
     6421 taggtataga atgtttggct atcgcagtaa cgtgccaaaa gtgcgcttaa ccaccgatcg
     6481 tctggtggta cgtttagtgc atgagcgtga tgcctggcgt ctggccgatt attacgcgga
     6541 aaatcgtcat tttttaaaac cctgggaacc ggtccgtgat gaaagtcatt gttatccttc
     6601 aggatggcag gcgcgtctgg gaatgatcgg tgaatttcac aaacagggct ccgccttcta
     6661 tttcgcgcta cttgatccgg aagaaaaaga aattatcggc gtggcgaatt tttccaatgt
     6721 ggtgcgcggt tcttttcatg cctgttatct gggctattcc attgcgcaag agtggcaggg
     6781 gcaagggctg atgtttgaag ccttaaccgc tgcgattcgc tatatgcagc gcactcagca
     6841 tatccaccgt atcatggcga actatatgcc gcacaacaaa cgtagcggcg cgttgctggc
     6901 gcggcttggc tttgaaaaag aaggctatgc gaaagattac ctgttgattg atggacaatg
     6961 gcgcgaccat gtcctgacgg cgttaaccac gccgttatgg acgccggggc gttgagcggc
     7021 ttacggaatg agaggcaaag ggagaaaacg atgaaatatg aattaaccgc cactgaagcg
     7081 cgagtgattg gctgtctgct ggaaaagcag gtgacaacgc cggaacagta tccgctttcc
     7141 gtcaacgggg tggtgacagc ctgtaatcag aaaaccaacc gtgaaccggt gatgaacctg
     7201 acggaacaag aggtacaaga acagctcgat aacctggtga aacgccactt tttgcgtacg
     7261 gtcagcgggt ttggcaaccg cgtcaccaaa tatgaacagc gcttctgtaa ttccgaattt
     7321 ggcgatctga aacttagcgc ggcggaagtg gcgctcgtca ctacgttgct gctgcgcggc
     7381 gcgcaaacgc ccggcgagtt gcgtagccgg gcgtcgcgga tgcatgaatt cagcgatatg
     7441 gcggaagttg aatccacgct ggaacggctt gccagtcgtg aggacggccc gtatgtcgtc
     7501 cgtctggcgc gtgaaccggg taagcgcgaa agccgctata tgcacctttt ttgcggcgac
     7561 gtcgatgaac tgtctctcca gacgtctgcg ccggaaagtg cgtcgggcga tcttcagtcg
     7621 cgcgtcgaag cgctggaaag cgaagtggcg gagttaaagc agcggctgga ttctttgtta
     7681 gctcacctgg gagagtaatg tgagaacatt acggattggc attgtcgtgt taggtggtat
     7741 tgcgcagaag gcctggctgc cggtattaac caacaccgcc ggatggacgt tacagggcgc
     7801 ctggtctcct tcgcgggata aagccttacg tatttgcgaa agctggcgca taccgtatgt
     7861 ggattcgctg gcgaatttag cgtccggctg cgatgcggtc ttcgtccact ccagtaccgc
     7921 aagccattat gccgtggtca gcgaacttct caacgctggc gtccatgtct gcgtggataa
     7981 accgctggcg gaaaatctac gtgatgccga acggctggtg gcgctggcgg cgcaaaaaaa
     8041 attgacgctg atggttggct ttaatcgccg tttcgcgccg ctgtaccgcg aactgaagac
     8101 gcgcctcggc actgcggcgt cactgcgtat ggataaacat cgtaccgata gcatcgggcc
     8161 gcatgactta cgttttactt tgctcgatga ctatctgcat gtcgtggata ccgttctgtg
     8221 gctggcgggc ggcgaggcgc gccttgccag cggcacgttg ctcaccagcg agtccggcga
     8281 aatgtgctat gcggaacatc atttttccgc cgacaaatta caaattacca ccagtatgca
     8341 ccggcgcgcc ggaagtcagc gtgaatcggt ccaggccgtc accgatggcg ggctgtatga
     8401 cgtgacggat atgcgtgaat ggcgcgaaga gcgcgggcag ggtattctca tcaaacccat
     8461 tccgggttgg caaacaacgc ttgagcagcg tggttttgtc ggatgcgcgc ggcatttcat
     8521 tgactgcgta caaaatcaga cggttccgga aacggcgggg gagcaggcga ttttggccca
     8581 gcgcgtcgtg gaggcgctgt ggcgggacgc catcagcgaa taatcctctg taacatctgg
     8641 cggtagtaat tcatcgtaat ccaggtacta taccctcaat aattcgagtt gcagaaaagc
     8701 taacgcacat gcagctcgaa gtatggcggg tatatatgcc cactctacat aatacctctt
     8761 ttcacagtga ataatggcaa accgtgggga gtctgtaagg cctgataaga cgttttgacg
     8821 tcgccgtcag gcgcagtgat acagccggat acggcagaag ttgcgttatc cggtcgatgg
     8881 atcagccatg caggagtttt acgccagggt ctggaataca aaagaaatga atttattgaa
     8941 atcgctggct gccgtcagct cgatgactat gttttcacgc gtgttgggct ttgcccgtga
     9001 tgcgattgtc gccagaattt ttggcgcagg gatggcgacc gacgcctttt ttgtggcgtt
     9061 taaacttccc aatctactac gccggatctt tgccgaaggc gctttttctc aggcctttgt
     9121 gcctatcctg gcggaatata agagcaagca gggtgaagaa gcgacgcgga tctttgtcgc
     9181 ttacgtttcc ggcctgttga cgctggcatt ggccgtcgtg acggtggccg gtatgctggc
     9241 cgccccgtgg gtgattatgg taaccgcgcc gggttttgcc gatactgcgg ataaatttgc
     9301 gctgacgacg caactgctgc ggattacgtt tccctatatt ctgctgatct cgctggcttc
     9361 actggttggc gccattctca acacctggaa tcgcttctct attcccgctt ttgcgccgac
     9421 atttcttaat atcagtatga tcggttttgc attattcgcc gcgccatact ttaatccgcc
     9481 ggtgctggcg ttagcctggg cagtcaccgt cggcggcgtg ctgcaactgg tgtatcaact
     9541 tccgtatttg aaaaagatcg gtatgctggt gctgccgcgc attaactttc acgacaccgg
     9601 ggcgatgcgg gtggtcaaac agatggggcc ggcgattttg ggcgtttccg tcagtcagat
     9661 ctcccttatc atcaatacca ttttcgcctc gtttctggcc tccggctcgg tctcatggtt
     9721 gtactatgcc gatcggttga tggagttccc gtccggcgtg ctgggcgtgg cgttggggac
     9781 catcctgttg ccgtcattgt cgaaaagctt tgccagcggc aatcatgatg agtactgccg
     9841 cctgatggac tgggggctgc gtttgtgctt tttactggcg ttgccgagcg cggtagcgct
     9901 aggcattctg gcgaagccgc tgacggtctc gctgtttcag tacggtaaat tcaccgcctt
     9961 tgatgcggcg atgacgcagc gggcgttaat cgcctattcg gtggggctga ttggcttgat
    10021 cgtcgtaaaa gtgctggccc cgggcttcta ttctcgccag gatattaaaa cgccggtgaa
    10081 aatcgccatc gtgacgttaa tcatgacgca gttaatgaac ctggcgttta ttggaccgct
    10141 gaaacacgcc gggctgtcgc tctctattgg tctggcggca tgtctcaatg cgtcgctgct
    10201 gtactggcaa ctgcgcaaac agaatatctt tacgccacaa ccggggtgga tgtggttcct
    10261 gatgcgtctg atcatttccg tactggtaat ggccgccgtg ttgttcggcg tgttgcatat
    10321 tatgccggag tggtcgcaag ggtcgatgct atggcgtttg ctgcgtttga tggcggtagt
    10381 gatcgcgggt atcgcggcct atttcgccgc gcttgccgtg ctgggcttta aagtgaaaga
    10441 gtttgttcgc cggacggcgt aaattcagtg cctgatagcg ctgtgctatc aggcctacaa
    10501 ggcattcagg ccggaaaggc gcaacgtcgc catccggcaa tgattagata gatatttttt
    10561 taccgccgcg gtgagagacg gaagtctgac cgtcagcccc gtacaaggtc ggctcctggt
    10621 gaggtttcag cacctccagc gcctgttgat tacgctcgat ttgcccttcc agcagccagc
    10681 cgttgtgctg gttgaggtcg cgcagatgct gcgttttttc ggtaatcgcc tgccagcgct
    10741 ctgcaatgtc atcgtttgcg ctacgctgcg cgttctgctc cagacggcgc tgttgttcca
    10801 gataatccag cgtcgccagc aacgagcttt tttcttctgt aatacgctgt agctggctgc
    10861 cgttaatctg gcctacggaa agctgttgtt gctcggcgtc catcaccgtc ttcaggtcat
    10921 tcaggacggt ggtcatctgg tcaagtattt ctgacaaacg agtcatacgc ttatttattc
    10981 tgtaagtagc tctgcgcctc gcgaatgagc gagtctgcta tttttcccgt atccattttt
    11041 aactcaccgt tacggatagc cgtttttaat gcttcgacgc gttccatatt aatgtcgctg
    11101 acgcctggct gcataagctt cgcttgcgcg tcgcttaacg ttacgctggc gctcgtcgcg
    11161 gcggacgttt tttcctgacg cgttttttgt accggcgtgt cgctagtttc gcgcgtctgg
    11221 acagtgctaa cgggtttcaa aggtgaggta cggtcaatgc tcatttattt atcctcatcg
    11281 agggttacgt tgtagcggcc agctaccatc atggttgaat atctcatcgg cagccgcgac
    11341 aaaatcttta cacaattata ggttaataag aatattccca tcagaatcga cggttccact
    11401 cacgatttga cccgatgtca tgcgcacgcg cgcattttgc gcgacggcgg cattattcat
    11461 cgcctgacct tccgcattga cgctaaaccc ctcgccattg gcgatgacct gtactcgttg
    11521 acccgctttg acacgccagg cctgacgtat catcgtaagc tgtaccggct gcccgggagc
    11581 gagatcgcgc aaactgacgg catcctgaat ctgacggata tccagtaccg tccgcggcgg
    11641 taactgatcc agtctgccac gttttagcgt gacgttggcc ggcgtcaatt ttccgccgcg
    11701 cgcgacgggc gcggctacgg cgacataatt gccggtcgct tgcacattca cctgcaaata
    11761 acgtttttca ttggcgcagc gcgccaccac attgacgttg ccccacagct tcgcgctgcc
    11821 cgtcatgctg aaggctggct gctcgcagct cggtagcaga ttgggcggtg aacggagcgt
    11881 gacaaccacc tcgtcgctga agccagccag acgctgggaa aaccacgtgg tcagctgggc
    11941 gttgatgtcc tgcgccattg tcagggggct gaacagcaaa gccgccacgg cgaatcctcg
    12001 ttttaacgtt tgcatggtac ttccccctgg ttgatgtcat gacaggattc tacccgtgtg
    12061 aagcaagcat caacgcaata aatagcgacg cattttgcgt ttattccggc gataacgcgc
    12121 gcgtgaaggc atttaagctg tcggctgaat tttgccattt gcggaggaga tatgctcgac
    12181 aggctcgatg ccgccttacg atttcagcag gaagcgctaa atctgcgcgc gcaacgtcag
    12241 gaaatattag cggcgaatat cgccaatgcc gatacgccgg ggtatcaggc gcgcgatatt
    12301 gattttgcca gtgagttaaa aaaagtgatg gtgcgcggac gggaagaaac cggcggcgtc
    12361 gcgttgtcgt tgacttcttc tcgccatatt cccgcccagg cggtctcttc tcccgcagtg
    12421 gatctgcttt accgcgtacc cgatcagcct tctttggatg gtaacaccgt agatatggac
    12481 agggaacgta cgcagtttgc ggataacagt ctcaaatatc agatggggct taccgttctg
    12541 ggtagccaac tcaaaggcat gatgaatgtg ctacagggag gaaactaatt cgtggcgctg
    12601 ttaaacattt ttgatattgc cggatcggcg cttgccgcac agtccaagcg gttgaacgtt
    12661 gcggccagta accttgcgaa tgcggatagc gtcaccggcc cggacggaca gccttatcgc
    12721 gccaaacagg tggtttttca ggtggacgcc gcgccgggtc aagccactgg cggggtaaag
    12781 gtcgccagcg tgattgaaag tcaggcaccg gaaaagctgg tttatgagcc aggcaatccg
    12841 ctggcggacg ctaatggtta cgtcaaaatg cccaacgtcg atgtggtcgg cgaaatggtc
    12901 aacacgatgt cagcctcgcg cagctatcag gcaaatatcg aagtcctgaa taccgtaaaa
    12961 agcatgatgc ttaaaacgct gacattaggc cagtaaagga ggcgcgtatg tctattgccg
    13021 taaatatgaa tgacccgacc aacacgggcg tcaaaacgac gaccggcagc gggtcgatga
    13081 ccggaagcaa cgctgccgat ctgcaaagca gtttcctgac cttactggtc gcgcaattga
    13141 agaaccagga cccgactaac ccattacaaa ataatgagtt aacgacacag ttggcgcaaa
    13201 tcagtaccgt gagcggcatt gaaaaactga atacgacgct gggggctatt tccgggcaaa
    13261 tcgataatag tcagtcccta caggcgacca cgctgattgg acatggcgtt atggtgcctg
    13321 gcaccacaat tctggcgggt aaaggcgcgg aagaaggggc cgtgacgtcc acgacgccgt
    13381 ttggcgtgga attgcaacag cctgcggaca aagtgacggc aaccattacc gataaagatg
    13441 gccgggtggt acggacgctg gagatcggtg agttgcgagc cggggtacac acctttacct
    13501 gggatggtaa gcaaacggac ggaacaacgg taccgaatgg ttcttacaac attgcgatta
    13561 ccgccagcaa tggcgggacg caactggtgg cgcagccgct gcaattcgct ctggtacagg
    13621 gcgtgacgaa gggcagtaac ggcaacctgt tggatctggg tacctacggc accaccacac
    13681 tcgacgaagt tcggcaaata atctaagccc ttacacttat caggagtcag tcatgtcttt
    13741 ttctcaagcg gttagcggcc tgaacgctgc ggccaccaac cttgatgtta tcggtaataa
    13801 catcgccaac tccgccacct atggctttaa gtccggtacg gcatcatttg ccgatatgtt
    13861 cgccggttcc aaagtggggt tgggcgtaaa agtggcgggg attacccagg attttaccga
    13921 cggtacgaca acgaacaccg ggcgcgggct ggatgtcgcg attagccaga acggtttttt
    13981 ccgcctggta gacagcaacg gttccgtgtt ctatagccgc aacggccagt tcaaactgga
    14041 cgagaaccgt aacctggtca atatgcaggg gatgcagttg accggctatc cggccaccgg
    14101 tacgccgccg accattcagc agggggcgaa tcctgcgccg atcaccattc cgaacacgct
    14161 gatggcggcg aaatcgacca ccaccgcgtc aatgcagatc aacctgaact caacggaccc
    14221 tgtaccgtct aaaacgccct ttagcgtgag tgatgcggat tcgtataaca aaaaaggcac
    14281 cgtcaccgtt tatgacagcc agggtaatgc ccatgacatg aacgtctatt ttgtgaaaac
    14341 caaagataat gaatgggctg tgtacaccca tgacagcagc gatcctgcag ccactgcgcc
    14401 aacaacggcg tccactacgc tgaaattcaa tgaaaacggg attctggagt ctggcggtac
    14461 ggtgaacatc accaccggta cgattaatgg cgcgacagcg gccaccttct ccctcagctt
    14521 ccttaactcc atgcagcaga acaccggggc taataacatc gtcgccacca atcaaaacgg
    14581 ctataagcct ggcgacctgg tgagctacca gattaacaat gatggcaccg tggttggcaa
    14641 ctactccaac gagcaggagc aggtgctggg gcagattgtg ctggctaact tcgccaacaa
    14701 cgaaggtctg gcatcccagg gcgataacgt ctgggcggcg acgcaggcct ccggggtagc
    14761 gctgctgggg actgccggtt ccggcaactt cggtaagctg acgaacggcg cgctggaagc
    14821 ctctaacgtg gatttgagta aagagctggt gaatatgatc gtcgcgcagc gtaactacca
    14881 gtcgaatgcg cagaccatca aaacccagga ccagatcctc aatacgctgg ttaacctgcg
    14941 ctaagcgcct gacgggatag cttaatggat cacgcaattt ataccgccat gggggcggcc
    15001 agccagacgc ttaaccagca ggcggtaacg gccagcaacc tggctaatgc ctcaacgccg
    15061 ggctttcgcg cgcagcttaa cgcgctacgc gcggtgcccg ttgatggcct ctctttagcg
    15121 acgcgcacgt tggttacggc gtcgacgccg ggggcggata tgacccaggg tcagttggac
    15181 tacacttccc gcccgctgga tgttgcgtta cagcaggacg gctggctggt ggtgcaagcg
    15241 gcggatggcg ctgaaggata tacccgtaac gggaatatcc aggtgggccc gaccgggcag
    15301 ttaaccattc agggacatcc ggttatcggc gaaggcggcc cgattaccgt tccggaaggg
    15361 tcggaaatca ccattgcggc agacggcacg atctccgcgc tcaatcccgg cgacccgcca
    15421 aacacggtgg cgcccgttgg gcggctgaag ctggtcaaag cggaaggcaa tgaggtgcag
    15481 cggagcgatg acggtttatt ccgccttacc gccgaggcac aggctgaacg cggggcggta
    15541 ctggccgccg acccgtcaat tcgcattatg tcgggcgtgc tggagggcag taacgtcaag
    15601 ccggttgaag ccatgaccga catgatcgcc aacgcacgtc gttttgaaat gcagatgaag
    15661 gttatcacca gcgtagatga gaacgaaggg cgagctaacc aactgctgtc gatgagttaa
    15721 tacaggacat tttatgatca gttcattatg gatcgccaaa accggtctgg acgcgcagca
    15781 aaccaatatg gatgtgattg ccaataacct ggcaaacgtc agcaccaatg gttttaagcg
    15841 tcagcgcgcg gtatttgaag atctgttgta tcagaccatc cgccagccgg gcgcgcagtc
    15901 gtccgagcag acgacgctgc cttccgggct gcaaatcggt accggcgtgc gtccggtcgc
    15961 cacggagcgc ctgcacagtc aggggaacct gtcgcagacc aacaacagta aagatgtggc
    16021 gattaaaggg cagggctttt tccaggtcat gctgccggac ggtacgtctg cctatacccg
    16081 cgacggctct ttccaggtgg atcagaatgg tcaactggtg acggcgggcg gttttcaggt
    16141 gcagccggca atcaccattc cggccaacgc gttaagcatc acgattggcc gcgacggcgt
    16201 ggtcagcgtt acccagcaag ggcaggccgc gccggttcag gtcgggcagc ttaacctgac
    16261 cacctttatg aacgacaccg gtctggaaag catcggcgag aacctctata tcgaaacgca
    16321 atcgtccggc gcgccgaacg aaagcacgcc ggggctcaac ggcgcggggt tgttgtatca
    16381 agggtatgtc gaaacgtcga acgttaacgt ggcggaagag ctggtgaaca tgattcaggt
    16441 tcaacgcgcc tatgaaatta acagtaaagc agtatcgacg accgatcaga tgctgcagaa
    16501 actgacgcaa ctctaagggg ccgccggtgg gggatacgcc accggctccc tgattttgaa
    16561 gatgaaggta atgcaaaaat acgcgcttca cgcttaccca gttatggccc tgatggtcgc
    16621 gacgctgaca ggatgcgcct ggatacccgc taaaccgctc gtgcaggggg cgaccacggc
    16681 gcagccgata cctggcccgg taccggtggc gaatggctcc atatttcagt ctgcgcagcc
    16741 gattaattat ggctatcagc cgctttttga agatcgtcga ccgcgtaata tcggcgatac
    16801 gctcacgatt gtgttacagg aaaacgtcag cgccagtaaa agctcgtcgg caaatgccag
    16861 ccgcgacggc aaaaccagct ttggttttga tacggtaccg cgttatctgc agggattatt
    16921 cggtaattcc cgcgcggata tggaggcctc cggcggcaac tcttttaatg gtaaaggcgg
    16981 cgcgaatgcc agcaatacct ttagcggcac gctgaccgtg accgtcgatc aggttctggc
    17041 caatggcaat ttacacgtcg tgggggaaaa acagatcgcg attaatcagg gaacggaatt
    17101 catccgcttc tccggcgtgg taaatccacg caccatcagc ggtagcaact ctgttccctc
    17161 gacacaggtg gcggatgcgc ggattgaata tgtcgggaac ggctatatta acgaagcgca
    17221 aaatatgggc tggctgcaac gtttcttcct taatttgtcg ccgatgtaag cgaggtgtat
    17281 gtgtttaaag ctcttgcagg aatcgttctg gcactggttg ccactctggc gcacgccgag
    17341 cgtatccggg atctgaccag tgtccaggga gtacgggaaa actcgctgat cggctacggg
    17401 ctggtggtcg ggctggacgg tacgggcgac cagacgaccc agacgccatt taccacccag
    17461 acgctgaata acatgctgtc acaactgggg attacggtcc ccaccggcac caatatgcag
    17521 ttgaaaaacg tggcggcggt gatggtgacg gcgtcgtatc cgccttttgc gcgacaggga
    17581 caaacgatcg atgtcgtcgt ttcctcaatg gggaacgcta aaagtctgcg tggcgggacg
    17641 ttattaatga cgccgttaaa aggggtggac agccaggtgt atgctctggc gcagggcaat
    17701 attctggtcg gcggcgcggg cgcttccgca ggcggcagta gcgtgcaggt taaccagctt
    17761 aatggcgggc gcatcactaa tggcgcgatt atcgaacgcg agttgccgac tcagttcggc
    17821 gctggcaaca ccattaatct gcaattgaac gacgaagatt ttacgatggc gcagcaaatt
    17881 accgacgcca tcaaccgcgc ccgcggttac ggcagcgcca ctgcgcttga tgcgcgaacg
    17941 gtacaggtac gcgtgcccag cggcaacagc tcgcaggtgc gttttctggc ggacattcaa
    18001 aatatggaag tcaacgtgac gccgcaggat gcaaaagtcg tgatcaactc gcgtaccggt
    18061 tcggtggtca tgaatcggga agtcacgctg gatagctgcg ctgtggcgca gggcaatttg
    18121 tcagtgacag tcaatcgcca actcaacgtc aaccagccga atacgccatt tggcggcggg
    18181 cagaccgtgg tgacgccaca gactcagata gatttgcgtc agagcggcgg atcgctacag
    18241 agcgtgcgtt ccagcgccaa tctgaacagc gtagtgcgcg cgctgaatgc gcttggcgcg
    18301 acgccgatgg atctgatgtc gattttgcag tccatgcaga gcgcgggctg tctacgcgcc
    18361 aaactggaaa tcatctgatg atcggagacg gtaaattgct ggccagcgcg gcctgggatg
    18421 cgcaatctct gaacgaactg aaagcgaaag cgggccagga cccggcggcg aatatccgtc
    18481 ctgtggcccg tcaggtggaa gggatgtttg tgcagatgat gctgaaaagt atgcgcgagg
    18541 ctttacccaa agatggttta ttcagcagcg atcagacgcg tctgtatacc agcatgtatg
    18601 accagcagat cgcccagcag atgaccgccg gtaagggatt ggggctggcg gatatgatgg
    18661 ttaaacagat gacgggcggg cagacgatgc ctgcagatga tgcgccgcaa gtaccgctta
    18721 aattctccct ggagacggta aacagctatc aaaatcaggc gctgacccaa ctggtgcgca
    18781 aagccatacc gaaaacgccg gacagcagcg atgcgccgct ctccggcgac agtaaagact
    18841 ttctggcccg gctttcgctc ccggcgaggc tggccagcga acaaagcggg gtgccgcatc
    18901 atctgattct ggcgcaggcg gcgctggagt ccggctgggg gcagcggcaa atcctgcggg
    18961 agaatggcga acccagctat aacgtatttg gcgtgaaagc gaccgccagt tggaaagggc
    19021 cggtgacgga aatcaccacc actgaatacg aaaatggcga agcgaaaaaa gtgaaagcga
    19081 aattccgcgt ctatagctcg tatctggagg cgttatcgga ttatgtcgcg ctgttaacgc
    19141 gtaacccacg ctacgctgcc gtgaccactg ccgccacggc agagcagggc gcagtggctc
    19201 tgcaaaacgc cggatacgcc actgacccga attacgcgcg taaattggcc agcatgattc
    19261 agcagttgaa agcgatgagt gaaaaggtca gcaaaaccta cagcgcgaat ctcgacaatc
    19321 tcttttaaat tgctcaagtc cacgtagtcg ctgccgataa caacgagtat tgaaggatta
    19381 aaaggaacca tcatgtccag cttgattaat cacgccatga gcggacttaa cgccgcgcag
    19441 gccgcgttaa atacggtcag taataacatc aacaattata acgttgcggg ttatacccgg
    19501 cagacaacta ttctggcgca ggcaaacagt acgttagggg ctggcggctg gataggtaat
    19561 ggcgtttacg tttcaggcgt acagcgcgaa tatgatgcgt ttatcactaa tcagctacgc
    19621 ggcgcgcaaa accagagcag cggcttaacc acgcgctatg aacaaatgtc gaaaatcgac
    19681 aacctgctgg ccgataaatc cagctcactg tctggctcgc tgcagagttt ttttaccagc
    19741 ctgcaaacgt tagtcagtaa tgcggaagat cctgcggcgc gtcaggcgct gattggtaaa
    19801 gcggaagggc tggtaaacca gttcaaaacc accgatcagt atctgcgcga tcaggataaa
    19861 caggtcaata tcgcgattgg ctccagcgtg gcgcaaatca acaattacgc gaagcagata
    19921 gctaacctga acgatcaaat ctcccgtatg acgggcgtag gcgcgggcgc atcgccgaac
    19981 gacctgctcg atcaacgtga tcagttggtt agcgagctta acaagatcgt tggcgtcgag
    20041 gtgagtgtac aggacggcgg cacctataac ctgacgatgg ccaatggcta tacgctggtg
    20101 caggggtcga cggcgcgtca gttggcggcg gttccctcca gcgccgaccc gacgcgaacg
    20161 actgtcgctt atgtcgatga ggccgccggt aacatcgaaa ttccggaaaa gttgctgaac
    20221 accggttcgc tcggcgggct actgacgttc cgttctcagg atctggatca gactcgtaat
    20281 acgctgggcc agttggcgtt ggcgtttgcc gatgcgttta acgcgcagca taccaaaggt
    20341 tatgacgccg acggcaataa agggaaagac ttctttagca ttggctcgcc ggtggtatat
    20401 agcaacagta ataatgccga taaaacggta tcgctaaccg ctaaggtggt cgacagcacg
    20461 aaggttcagg cgacggatta taagattgtt tttgacggta cagactggca ggttactcgc
    20521 actgcggata acaccacctt cacggcaaca aaagatgctg acggaaaact ggagattgac
    20581 ggtctgaaag tgacggtagg gactggcgca cagaaaaacg acagttttct tctcaagccg
    20641 gtcagcaatg ctatcgtcga catgaacgtt aaagtgacaa atgaagccga gattgcgatg
    20701 gcgtctgagt caaaactcga tcctgatgtg gataccggcg acagcgataa ccgcaatggt
    20761 caggcattgc tggacttaca aaacagcaat gtagtgggcg gcaacaaaac ctttaacgat
    20821 gcttacgcca cgttggtcag cgatgtgggt aacaaaacgt caacgctgaa aaccagcagc
    20881 accacgcagg cgaatgtggt taaacagctt tataaacagc aacagtcggt ttccggcgtt
    20941 aacctcgacg aagagtacgg caatttgcag cgttatcagc agtattatct ggcgaatgcg
    21001 caagtattgc agaccgcgaa tgcgctgttt gatgcgttat tgaatattcg ctaaaggaga
    21061 aggatgacat gcgtatcagt acccagatga tgtacgaaca aaatatgagc ggcatcacta
    21121 attctcaggc cgaatggatg aagctgggcg agcagatgtc taccggtaag cgcgttacca
    21181 acccatctga cgatccgatc gccgcgtcgc aggcggtagt actctttcag gcgcaggcgc
    21241 agaatagcca gtacgccctg gcgcgtacgt ttgccaccca aaaagtgtcg ctggaagaaa
    21301 gcgtactcag tcaggtgacg acggcgattc aaaccgcgca ggaaaaaatc gtctatgccg
    21361 gaaacggcac gttaagcgac gatgaccgcg cgtcgctggc gacggattta caggggatcc
    21421 gcgatcagct gatgaacctg gcaaacagca ctgacggcaa tggtcgctat atctttgccg
    21481 ggtataaaac ggaagcggcg ccattcgacc aggcgacagg tggttatcat ggcggcgaga
    21541 aaagtgttac ccagcaggtg gattccgcac gcacgatggt aattggccat acgggagcgc
    21601 aaatttttaa tagcatcacc agcaatgcgg tgccggaacc ggatggctcg gactccgaaa
    21661 agaatctgtt tgtcatgctc gatacggcaa ttgccgcgct caagaccccg gtggaaggca
    21721 atgacgtgga aaaagaaaaa gccgctgccg ccattgataa aaccaatcgc ggcttaaaaa
    21781 attcgcttaa taacgtcctg accgttcgtg cggaactggg aacgcaactg agcgaactca
    21841 gtacgctgga ttcactggga agcgaccgtg cgctgggaca gaagctacag atgagcaacc
    21901 tggtagatgt ggactggaac tcggtcattt cctcctacgt catgcaacag gcggcattac
    21961 aggcgtccta taaaacgttt accgacatgc agggaatgtc gcttttccag ttgaaccggt
    22021 aacgcctctt tttgaaacat atcacgaaac tggatatgtt ttgtctgccc gcgccatcca
    22081 ccccggcgcg ggc
//
LOCUS       DAJVKX010000071        22006 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000071 DAJVKX010000000
VERSION     DAJVKX010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22006
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.071"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            82..480
                     /locus_tag="OPY25_002744"
                     /pseudo
     CDS             82..480
                     /locus_tag="OPY25_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
     gene            complement(556..1761)
                     /locus_tag="OPY25_002745"
     CDS             complement(556..1761)
                     /locus_tag="OPY25_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCS0928326.1"
                     /translation="MLILKAYKFRLEPTPEQSQRLRQLCGCARFVWNLGLAETKRILG
                     SGEKLPSAFELNRMLTVWKKMPGHIFLQDAYTDNLQQKLKDLHTAWKRCFDKKLAAKA
                     PVWKRKNEGRDSIRFVNFEKYCRLENRRVKLPSGLGWVKFRQSQRVNGKIKNATISQL
                     AGQWYISFQVEVETAEPNHTSTTIVGLDAGVTKLATLSDGTVYQPVNSFKASQRKLAT
                     LQRQLSRKVRFSSNWQKQKRKVQHLHSHIANIRRDYLHKVTSEISKNHAMIVIEDLKV
                     SNMSKSAKGTAEQHGRNVKAKSGLNRSILDQGWYEMRRQLEYKQLWRGGQVLAVPPAY
                     TSQRCACCGHTAKENRLSQSKFVCQACGYTANADVNGARNILAAGHAVLACGGMVQSG
                     RPSETGTRR"
     gene            1784..2224
                     /gene="tnpA"
                     /locus_tag="OPY25_002746"
     CDS             1784..2224
                     /gene="tnpA"
                     /locus_tag="OPY25_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSen6 family
                     transposase"
                     /protein_id="HCS0928327.1"
                     /translation="MFATLLFLRSTSIQKHKINRSRHAAFLLHVHLVFVTKYRRKILG
                     ESHYAAFHQYAAEVCRDFGGELKESNGDVDHVHMLIEYPPTVQLSVLVNSLKAVTSRR
                     LRNEFIDLRGAYGKAVLWSRSYFAGSCGGAPLEVVKQYIQHQRG"
     gene            2290..2520
                     /locus_tag="OPY25_002747"
     CDS             2290..2520
                     /locus_tag="OPY25_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928328.1"
                     /translation="MELRWCTALLVSDPLHMLRLKTIAQDNGIDSRSSPTRATRYKSW
                     WAQTRFLLRETFYYSGYRLLRYMPVQNNSITP"
     gene            2564..4915
                     /gene="polB"
                     /locus_tag="OPY25_002748"
     CDS             2564..4915
                     /gene="polB"
                     /locus_tag="OPY25_002748"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HCS0928329.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQATLAPQESVAF
                     IPTSQTSRAASLLQAEKDYRLTPLQLRDFHHQPVSGLYCRTHRQLMRMEKLLRENGVT
                     VYEADVRPPERYLMERFITSPVWVDGEMRNGVIRNARLKPHPDYRPPLKWVSLDIETT
                     RHGELYCIGLEGCGQRTVYMLGPANGDERQLDFELVYVASRPQLLEKLNAWFAEHDPD
                     VIIGWNVVQFDLRMLQKYAERYRIPLRLGRDNSELEWREHGFKNGVFFAQARGRVIID
                     GIDALKSAFWNFSSFSLEAVSQELLGEGKSIDNPWDRMDEIDRRFAQDKPALATYNLK
                     DCELVTRIFHKTEIMPFLLERATINGLPVDRHGGSVAAFGHLYFPRMHRAGYIAPNLG
                     EVPPLASPGGYVMDSQPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVSQIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHAIMRQTKALIEAQGYDVIYGDTDSTFVWLRRAHSEADAAEIG
                     HRLVRHVNEWWAQTLQQQNLTSALELEFETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DSQRMVFKGLETVRTDWTPLAQRFQQELYLRVFRNEPYQDYVRETIDKLMAGELDAQL
                     VYRKRLRRPLHEYQRNVPSHVRAARLADEQNLKQGRPAQYQNRGAIKYVWTVNGPEPV
                     DYQQSPLDYEHYLTRQLQPVAEGILPFVEDNFATLLTGQLGLF"
     gene            5089..7995
                     /gene="rapA"
                     /locus_tag="OPY25_002749"
     CDS             5089..7995
                     /gene="rapA"
                     /locus_tag="OPY25_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HCS0928330.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAMDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDL
                     LVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSD
                     RDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLE
                     QGRDRLLEINSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVL
                     TPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLSAVNRHTGSKLVNAVQQDVHAILQLGETQIEQSARALIDNARREADEKL
                     SGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRLIVVTHQ"
     gene            8007..8666
                     /gene="rluA"
                     /locus_tag="OPY25_002750"
     CDS             8007..8666
                     /gene="rluA"
                     /locus_tag="OPY25_002750"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HCS0928331.1"
                     /translation="MGMENYNPPQEPWLVILYQDEHIMVVNKPSGLLSVPGRLEAHKD
                     SIMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYNVVEFAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDQFYASPEALSLAPRLQLHAEMLTITHPAYGNSMTFKVPAD
                     F"
     gene            complement(8761..9573)
                     /gene="djlA"
                     /locus_tag="OPY25_002751"
     CDS             complement(8761..9573)
                     /gene="djlA"
                     /locus_tag="OPY25_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HCS0928332.1"
                     /translation="MQYWGKIIGVAVALMMGGGFWGVVLGLLVGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGDSRTAAQNAFR
                     VGKADNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNEREVLYVIAEE
                     LGISRVQFDQFLRMMQGGAQFGGGYHQQSGGGWQQAQRGPTLEDACNVLGVKTTDDAT
                     TIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAYELIKEQKGFK"
     gene            9827..12181
                     /gene="lptD"
                     /locus_tag="OPY25_002752"
     CDS             9827..12181
                     /gene="lptD"
                     /locus_tag="OPY25_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HCS0928333.1"
                     /translation="MKKRIPTLLATMIASALYSHQGLAADLASQCMLGVPSYDRPLVK
                     GDTNDLPVTINADNAKGNYPDDAVFTGNVDIMQGNSRLQADEVQLHQKQAEGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTKNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLTQAGAGLMELDYLPSDKVYEDEHPKEGDKHRWLFYWQHSGVMDQVWRFNVDYTKV
                     SDSSYFNDFDSKYGSSTDGYATQKFSVGYAVQNFDATVSTKQFQVFNDQNTSSYSAEP
                     QLDVNYYHNDLGPFDTRIYGQAVHFVNTKDNMPEATRVHLEPTISLPLSNRWGSLNTE
                     AKLMATHYQQTNLDWYNANNSKKLEDSVNRVMPQFKVDGKLVFERDMAMLAPGYTQTL
                     EPRVQYLYVPYRDQSGIYNYDSSLLQSDYNGLFRDRTYGGLDRIASANQVTTGVTTRI
                     YDDAAVERFNVSVGQIYYFTESRTGDDNIKWENDDKTGSLVWAGDTYWRISERWGLRS
                     GVQYDTRLDSVATSSSSLEYRRDQDRLVQLNYRYASPEYIQATLPSYYSTAEQYKNGI
                     NQVGAVASWPIADRWSIVGAYYFDTNSSKPADQMLGLQYNSCCYAIRVGYERKLNGWD
                     NDKQHAIYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQSSM"
     gene            12235..13521
                     /gene="surA"
                     /locus_tag="OPY25_002753"
     CDS             12235..13521
                     /gene="surA"
                     /locus_tag="OPY25_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HCS0928334.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIILQMGQKMGVKITDEQLDQAIAN
                     IAKQNNMTMDQMRSRLAYDGLNYSTYRNQIRKEMIISEVRNNEVRRRITVLPQEVDAL
                     AKQIGTQNDASTELNLSHILIALPENPTSEQVNDAQRQAESIVEEARNGADFGKLAIT
                     YSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGQ
                     SQSISVTEVHARHILLKPSPIMNDQQARLKLEEIAADIKSGKTTFAAAAKEYSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTKLHKGQISAPVHSSFGWHLIELLDTRKVDKTDAA
                     QKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN"
     gene            13521..14510
                     /gene="pdxA"
                     /locus_tag="OPY25_002754"
     CDS             13521..14510
                     /gene="pdxA"
                     /locus_tag="OPY25_002754"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HCS0928335.1"
                     /translation="MSSAQRVVITPGEPAGIGPDLVVQLAQRAWPIELVVCADGALLT
                     ERAAMLGLPLSLLPYSPDVPAAPQPAGTLTLLPVSLRAPAIPGQLTVENGPYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRAIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     gene            14507..15328
                     /gene="rsmA"
                     /locus_tag="OPY25_002755"
     CDS             14507..15328
                     /gene="rsmA"
                     /locus_tag="OPY25_002755"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCS0928336.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDRFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDKLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELSA
                     QLGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPYPVKDIRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVETLTEMGIDPAMRAENISVAQYCQMANYLSENAPLKES"
     gene            15331..15708
                     /gene="apaG"
                     /locus_tag="OPY25_002756"
     CDS             15331..15708
                     /gene="apaG"
                     /locus_tag="OPY25_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HCS0928337.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDDERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGHGRETEVQGKGVVGVQPRIAPGEEYQYTGGAVIETPLGTMQGHYEMI
                     DENGDAFTIDIPVFRLAVPTLIH"
     gene            15719..16567
                     /gene="apaH"
                     /locus_tag="OPY25_002757"
     CDS             15719..16567
                     /gene="apaH"
                     /locus_tag="OPY25_002757"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HCS0928338.1"
                     /translation="MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPG
                     SLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVS
                     EAYSIAFGHWASLEGKGTPEGIYALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGE
                     GEAVNA"
     gene            complement(16663..17142)
                     /gene="folA"
                     /locus_tag="OPY25_002758"
     CDS             complement(16663..17142)
                     /gene="folA"
                     /locus_tag="OPY25_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HCS0928339.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGR
                     HTWESIGRPLPGRKNIIISSQPGTDDRVQWVKSVDEAIAACGDAPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(17341..19203)
                     /gene="kefC"
                     /locus_tag="OPY25_002759"
     CDS             complement(17341..19203)
                     /gene="kefC"
                     /locus_tag="OPY25_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HCS0928340.1"
                     /translation="MDSHTLLQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVVCGGLIG
                     LFCMFLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQVGRSAFAVLLFQDIAAI
                     PLVAMIPLLAASGASTTLGAFALSALKVAGALALVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLVENPLRILLLLAGFLAIKIVMLWLVARTLGVPAKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMADVLEPEWAKALTLAVALSMAATPIFLVLLTRMEKTATGEAREA
                     DEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLSELVKTHFPHLQIIARARDVDHYIRLRQ
                     AGVAMPERETFEGALKSGRQALEALGLGRYEARERADLFCHFNTRMVEEMAKGENDPL
                     SRAAAYKRTSAMLSEIITEDREHLSLIQRHGWQGTAEGKHSGKAADEPEVKPSI"
     gene            complement(19196..19726)
                     /gene="kefF"
                     /locus_tag="OPY25_002760"
     CDS             complement(19196..19726)
                     /gene="kefF"
                     /locus_tag="OPY25_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HCS0928341.1"
                     /translation="MILIIYAHPYPHHSHANKQMLEQAGTLENVEIRSLYHLYPDFNI
                     DVAAEQEALSRASLIVWQHPMQWYSVPPLLKLWMDKVLTHGWAYGHGGTALHGKHLLW
                     AVTTGGGENHFAIGSHPGFAVLSQPLQATALYCGLKWLPPFAMHCTFICDDDTLQAQA
                     RQYKQRLLAWQEVNHG"
     gene            complement(20133..21931)
                     /locus_tag="OPY25_002761"
                     /pseudo
     CDS             complement(20133..21931)
                     /locus_tag="OPY25_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000948383.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
BASE COUNT         5216 a         6080 c         5707 g         5003 t
ORIGIN      
        1 cgtcagcaaa aatatctgac gctaaaagcc attttatcgt taaaatattc attacacccg
       61 tcacggggaa cgaactcatt catgaaatat cgctacatcc tcagaatcgc ggcaggcatc
      121 attctcatta tggccatggt gtttatccat aacgctatcg ctatttatca gttcagtcag
      181 caaaaccaga cgcgcgtagc tgactgcgcg attgtcgcag gagcaggcgt tagcggaaaa
      241 acgccttctc ccgtttttca ggccagactg gatcatgcca tctggcttta ccaacaacac
      301 attgtccgcg cgttggtatt aaccggcggc tacggcgctg gcgcaacggt ttccgacgcg
      361 gcgatagccc gtcaatacgt tctggaaaaa ggcattccgg ctaaggcgat ttttattgaa
      421 gagcgctcta ccgtgacgcg cgaaaatatt cgttacgcaa aacagatact gcgacaacaa
      481 cattgacatc ctcccccacc ttcgcacttc gtgactcagg tggggaattc ccattagtgg
      541 gtgacgactg attgctcagc gtctggttcc tgtttcagac gggcggcctg actgcaccat
      601 ccctccacag gcaagaacgg cgtgccccgc cgctaaaatg ttacgagcgc cgtttacatc
      661 agcgttcgct gtatatccgc atgcctgaca cacaaattta ctttgtgaca ggcgattttc
      721 tttcgcggta tgaccacagc acgcgcaacg ctggcttgtg tatgctggcg gaaccgcaag
      781 cacctgaccg ccacgccaga gctgtttgta ctcaagctgg cggcgcattt cataccagcc
      841 ctgatccagt atcgaacggt tcagacctga tttggccttg acgtttcgtc cgtgctgttc
      901 tgctgtacct tttgccgatt tcgacatgtt actaaccttc aaatcctcaa tgactatcat
      961 cgcgtggttt ttgctgattt cactggtaac tttatgaagg tagtcgcgcc ggatattggc
     1021 tatgtgcgag tgcagatgct ggacttttcg cttttgtttc tgccagttac tgctgaatct
     1081 gactttacgg cttaactgcc gctggagtgt tgccagcttg cgctgacttg ctttaaaact
     1141 gttgactggt tggtataccg taccgtctga aagcgtggcg agttttgtta ctcctgcgtc
     1201 cagaccgact atcgttgtgc ttgtgtgatt gggttctgcc gtttcaactt caacctgaaa
     1261 cgagatatac cactgtcccg ctaactgact gattgtcgca tttttgattt taccgttcac
     1321 acgttgagat tgccggaatt ttacccaccc aagacctgac ggtagcttca ctctgcgatt
     1381 ttcaaggcgg caatatttct caaagttcac aaaacggatt gagtctctgc cctcattttt
     1441 tcgtttccat accggggcct tagctgcgag ctttttatca aagcaacgtt tccatgcagt
     1501 atgcaggtct ttcaactttt gttgcagatt gtcggtataa gcatcctgta aaaagatgtg
     1561 tcccggcatt tttttccaca ctgtaagcat cctgttcaac tcgaaagccg aaggtaactt
     1621 ttcgcctgaa ccaaggatgc gctttgtctc cgcaagacct aaattccaga caaaacgggc
     1681 gcaaccacat aactgccgca aacgctgcga ctgttcaggc gttggttcca gtctgaattt
     1741 gtaggctttc aggattagca tcatcactca gtgtgtagga gatttgtttg ctacgttact
     1801 gtttttacgg tcaacttcaa tacaaaaaca taaaattaat cgttcaagac atgccgcctt
     1861 ccttttgcat gttcatcttg tctttgtaac aaaataccgt cgaaagatac tgggtgagtc
     1921 acactatgct gcattccatc agtatgcagc agaagtctgc cgtgattttg gcggagaact
     1981 taaagaaagt aacggagacg tcgatcatgt ccacatgctg atcgaatacc caccaacagt
     2041 gcagctttcg gtactggtta actcactgaa agctgtgaca tcccgccgtc tgcgaaacga
     2101 atttattgat ttgcggggag catacggaaa agccgtgctc tggtcgaggt catactttgc
     2161 tggctcgtgc ggaggtgcgc cgctggaagt tgtgaagcaa tacattcaac atcagcgtgg
     2221 ctgatgatcc ttcgggcttt tcaagcccgt ccaaattccc ctcccgcctt atgtcggcgg
     2281 gagtaccctt tggagttaag atggtgcaca gcgttactgg tcagcgatcc gctgcatatg
     2341 ctgcgtctga aaactatcgc tcaggataat ggtatcgata gccgctcatc acccacgcga
     2401 gccacccgct ataaatcctg gtgggcgcaa acccgcttct tactgcgaga aactttttat
     2461 tacagcggat atcggctttt acgttatatg cctgtacaaa ataacagtat taccccctaa
     2521 aacaggttat aattagcgtg aattttttag acaggtaatc atcgtggcgc aggcaggttt
     2581 cattttaacc cggcactggc gggatacgcc gcaagggacg gaggtctctt tctggctggc
     2641 gacagacaac ggccctttgc aggcgacgct ggcgccgcaa gagtccgtgg cgtttattcc
     2701 gaccagccag acctcccgcg ccgcctcgct gctacaggcg gaaaaagact atcgcctgac
     2761 gccgctccag ctgcgagact ttcaccatca gccggtatcc ggtctgtatt gccgcactca
     2821 ccgccagctt atgcggatgg agaaactgct gcgcgaaaac ggcgtcaccg tttatgaagc
     2881 ggatgtccgc ccgccggagc gttacctgat ggaacgtttt atcacttcgc ctgtttgggt
     2941 agatggcgag atgcgcaacg gcgttatccg caatgcgcgt cttaaacccc accccgacta
     3001 tcgaccgccg ctaaaatggg tctcgctgga tatcgaaacc acgcgacacg gcgagctgta
     3061 ttgcattggt ctggaaggct gcggccagcg taccgtttat atgctgggcc cggcgaacgg
     3121 cgatgagcgc caactggact tcgagcttgt gtatgtcgcc agccgcccgc agttgctgga
     3181 aaaactcaac gcctggtttg ccgaacatga tcctgacgtc atcatcggct ggaacgtggt
     3241 gcagttcgac ctgcgtatgc tgcaaaaata tgccgaacgc taccgtatcc ctttacggct
     3301 ggggcgagac aatagcgaac tggagtggcg cgaacatggc ttcaaaaacg gcgttttttt
     3361 cgcccaggcc agagggcgag tcattatcga tggtatcgac gcgcttaaat ccgcgttctg
     3421 gaatttttcg tctttttcgc tggaagccgt ctcgcaggaa ctgctcggcg aaggaaaatc
     3481 cattgataac ccctgggatc gtatggatga gatcgatcgc cgctttgccc aggataaacc
     3541 cgccctcgcc acctacaacc tgaaagactg cgagctggtc acgcgcattt tccataaaac
     3601 cgaaatcatg ccgtttttgt tggaacgcgc gacgatcaac ggcctgccgg tcgatcgcca
     3661 cggcggttcg gtcgccgcat tcgggcatct ttactttccg cgaatgcacc gcgccggcta
     3721 tatcgcgccc aatctcggcg aagtgccgcc gctggcaagt cccggcggct acgtaatgga
     3781 ttcacaaccc ggattatacg attcagtact ggtgctggat tataaaagcc tgtacccgtc
     3841 aattatccgc acgtttttga ttgatcccgt cgggctggtc gaaggcatgg cgcagccgga
     3901 cccggaacac agtaccgaag gtttccttga cgcctggttt tcacgagaaa agcactgcct
     3961 gccggaaatt gttagccaaa tctggcacgg gcgcgatgaa gccaaacgtc agggcaataa
     4021 accgctctcg caggcgctta aaatcattat gaacgccttt tatggcgtac tcggcaccac
     4081 ggcctgtcgc tttttcgatc cccgtctggc gtcgtcaatc accatgcgcg gtcatgcgat
     4141 tatgcgccag accaaagcgc tgattgaggc gcagggttat gacgtgattt atggcgatac
     4201 cgattccact ttcgtctggc tccggcgcgc gcattcagaa gccgatgcgg cggaaatcgg
     4261 gcacaggctg gtgcgtcacg tgaacgaatg gtgggcgcag acgttacaac agcaaaattt
     4321 gaccagcgcg ctggaactgg agtttgaaac tcacttttgc cgttttctga tgccgaccat
     4381 ccgcggcgcg gatactggca gtaaaaaacg ctacgcgggc ctgattcagg aaggcgacag
     4441 ccagcgcatg gtatttaaag gtctggaaac ggtgcggacc gactggacgc cgctggcgca
     4501 gcgctttcaa caggagctgt atctgcgcgt ttttcgcaat gaaccttatc aagactatgt
     4561 gcgcgagact atcgataaac tgatggcggg cgaactggac gcgcagctgg tttatcgtaa
     4621 gcgtctgcgt cgccctttac atgagtacca gcgtaacgtt ccgtcgcacg ttcgcgccgc
     4681 ccggctggcg gatgaacaaa acctgaagca gggtcgtccg gcgcagtatc agaatcgcgg
     4741 cgccataaaa tatgtctgga ctgttaacgg ccccgagccc gtggattacc agcagtcgcc
     4801 gctggattac gaacactatc ttacccgcca gctacaaccc gtggcggaag gaattcttcc
     4861 cttcgttgaa gataattttg ctacactact gaccgggcaa ctggggttat tttgacgcgt
     4921 gacgaaagcg ccgccttcca gtaccatagc gccctttcca ttcctggacc taattaacgc
     4981 cactaccaca ttagcctggt agcggggtcg tatactcgca attatccagt gctgtcgcct
     5041 gggaatggcg agtaatgcct gcaattaaag atatagagcc gaacacatat gccttttaca
     5101 cttggtcaac gctggatcag cgatacagaa agcgagctgg gacttggaac cgttgttgcg
     5161 atggatgcgc gaaccgtcac cttacttttc ccgtccacgg gggaaaaccg cctgtatgcg
     5221 cgcagtgatt ctcccgtgac ccgcgtcatg ttcaaccctg gcgatacgat tacaagccat
     5281 gaaggctggc agctacatat cgatgaagta aaagaagaaa atggcctgct tgtttatgtc
     5341 ggcacccgcc tggataccga agaaaccaat gtgacgttgc gcgaagttct gctcgacagc
     5401 aagttggttt tcagtaagcc ccaggatcgt ctgttcgccg gtcaaatcga tcgaatggat
     5461 cggttcgcgc tgcgctatcg cgcccgtaaa tttcagagcg agcagtaccg gatgccatac
     5521 agcggcctgc gcggtcagcg gaccaacctg atcccgcatc agcttaatat cgctcatgat
     5581 gtgggtcgtc gccacgcgcc gcgcgtactg ctggcggatg aagtgggctt aggtaaaacc
     5641 attgaagccg ggatgattct gcatcaacag ttattatccg gcgcggcgga acgcgtattg
     5701 atcatcgttc cggaaaccct gcaacaccag tggctggtag aaatgctgcg ccgtttcaac
     5761 ctgcgcttcg cgctgttcga tgacgaacgc tataccgaag cgcagcacga cgcgtataac
     5821 ccgtttgaaa ccgaacaact ggtgatctgc tcgctggatt tcgcccgccg caataagcag
     5881 cgtctggaac atttgtgcga cgccgagtgg gatttgctgg tggtcgacga agcgcatcat
     5941 ctggtgtgga gcaccgatgc gccgagccgt gaatatatgg ccatcgaaca gttagctgaa
     6001 cgcgtgccgg gcgtgctgct gctgaccgcc acgccagaac agctggggat ggaaagccat
     6061 ttcgcccgtc tgcgcctgct cgatccgaac cgtttccacg atttcgaaca gtttgtcgaa
     6121 gaacagaaaa actaccgccc tgtcgccgat gcggtggcca tgctgctggc gggcaataaa
     6181 ctcagcaacg acgaactgaa cagactgggc gatctgatcg gcgaacagga tattgaaccg
     6241 ctgttacagg ccgctaatag cgatcgcgac gacgcgcagg ccgcccgtga tgagctggtg
     6301 tcgatgctga tggatcgcca cggtaccagc cgcgttctgt tccgcaacac ccgtaacggc
     6361 gtcaaggggt tcccgaaacg tgaactgcat acggtaaaac tgccgctgcc gacccagtat
     6421 cagaccgcca ttaaggtctc cggcattatg ggcgcgcgta aaagcgcgga agatcgcgcc
     6481 cgcgatatgc tctatccgga acaaatttat caggagttcg aaggcgatac cggcacctgg
     6541 tggaacttcg acccacgcgt tgagtggctg atgggctatc tgaccagcca tcgttcgcaa
     6601 aaagtgctgg tgatctgcgc caaggcgacc accgcgttac agctggagca ggtgctgcgc
     6661 gaacgcgaag gcatccgcgc cgccgtgttc catgagggca tgtcgattat cgaacgcgac
     6721 cgcgccgccg cctggttcgc cgaagaagat accggcgcgc aggtgctgtt atgttccgaa
     6781 atcggctccg aaggacgtaa cttccagttt gccagcaatc tggtgatgtt cgacttgccg
     6841 tttaacccgg atctgctgga acagcgtatt ggtcgtctgg atcgtatcgg ccaggcgcat
     6901 gatatccaga tccacgtccc gtacctggaa aaaaccgccc agtcggtgct ggttcgctgg
     6961 tatcacgaag ggctggacgc ctttgagcac acttgcccga ccggtcgcgc gatttatgat
     7021 tcagcctacg ccagtctgat taactatctg gccgcgcctg aagaaaccga cgggtttgac
     7081 gatctgatca aatcctgccg cgaacaacat gaagcgctaa aagcccagtt agaacagggc
     7141 cgcgaccgcc tgctggagat caactccaac ggtggtgaaa aagcccaaca gcttgcacaa
     7201 agcattgaag aacaggacga cgacaccaac ctgatcgcgt tcgccatgaa cctgttcgat
     7261 atcgtcggca ttaaccagga tgatcgcggc gacaacctga tcgtgctgac gccgtccgac
     7321 cacatgttgg tgccggattt ccccggcctg ccggaagacg gttgtactat cacgtttgaa
     7381 cgtgacgtag ccctgtctcg cgaagatgcg cagtttatta cctgggaaca tccgctcatc
     7441 cgtaacggac tggatctgat cctctccggc gataccggca gcagcaccat ttcgctgttg
     7501 aaaaataaag cgctgcccgt cggcacgctg ctggtcgaac tggtttacgt cgtggaagcg
     7561 caggcgccga aacagctaca actgaaccgc ttcctgccgc cgacgccggt acgtatgctg
     7621 ttagataaaa acggcaacaa tctggccgcc caggtcgagt ttgaaacctt caaccgccag
     7681 ctcagcgccg tgaatcgcca caccggtagc aaactggtga acgccgttca acaggacgtc
     7741 cacgccattt tgcaactggg cgagacgcag attgaacagt ccgccagagc gctgattgat
     7801 aacgcgcgcc gcgaggcaga tgaaaaactg tccggggaac tgtcgcgtct ggaagcgctg
     7861 cgcgccgtca acccgaacat ccgcgacgac gaacttgccg ctatcgacag caaccgtcag
     7921 caggtgctgg aaagcctgaa tcaggcaggc tggcgtctgg acgcgctgcg tcttatcgtc
     7981 gtcacgcacc aataacggag ccgtacatgg ggatggaaaa ctacaatccg ccgcaggaac
     8041 cctggctggt tatcctgtat caggatgagc acattatggt ggtcaataag cccagcggcc
     8101 tgttgtccgt gccggggcgt ctggaagcgc acaaagacag cattatgacg cgtatccagc
     8161 gcgactaccc gcaggcagag tcggtgcatc gtctggatat ggccaccagc ggcgtgattg
     8221 tagtggcgct gaccaaagcc gcggagcggg agctaaaacg ccagttccgc gaacgtgagc
     8281 cgaaaaagca gtatgtggcg cgcgtatggg ggcatccctc cccggcggaa ggactggtcg
     8341 acttaccgct catctgcgac tggccgaacc ggccaaagca gaaagtgtgt tatgaaaccg
     8401 gcaaaccggc gcaaacggaa tataacgtgg tggaatttgc ggcggataat accgcccgcg
     8461 tggtgctcaa accgatcacc gggcgttcgc atcagctgcg tgtgcatatg ctggcgttag
     8521 gccacccgat cttaggcgat cagttttacg cctcgccgga agcgttgtcg ctggcgccgc
     8581 gtttgcagtt acacgccgaa atgctgacca ttacccatcc cgcttacggt aacagcatga
     8641 cgtttaaagt cccggcagat ttttaaattc tgagccaatt tatgccggag cgcttcgctt
     8701 gcccggccta cattcattaa cgtaggccgg ataaggcgct agccgcatcc ggcaattcaa
     8761 tcacttgaag cctttctgtt ctttgattag ctcatacgct ttctgaattt cctgcgcttt
     8821 ttgcttcgcc atctccatca tttccggcgg caaccctttg gccaccagct tatcgggatg
     8881 atgctcgctc atcagtttgc gataagcgcg tttaatggtg gttgcatcat cggtggtttt
     8941 aacccccagc acattacagg catcttccag cgtcgggccg cgctgcgcct gctgccagcc
     9001 gccgccggac tgttgatgat aaccgccgcc aaactgcgcg ccgccctgca tcatgcgcag
     9061 aaactgatcg aactgtacgc gggaaatacc taactcttcc gcaatcacat acagcacttc
     9121 ccgctcatta gggtgcagtg aaccatcggc aaacgccgcc tggatctgaa tttccagaaa
     9181 catccggatc agatcaaaac gcccgaagca gacgctacga aactgccgca tcttttcacg
     9241 taatgggtaa ttatccgctt ttccgacccg aaaggcgttc tgcgcggcag tacgtgaatc
     9301 gccgtgtaaa ttcatacgat ccatcaactg actggcgata tgaatatccg cttccgtcac
     9361 ccgtcctttt gatttggtta agtggcccat cacctcaaag gtggtggcaa aaaacagcgc
     9421 ctgccgttcc cgctggttgg caaaccacgc catttttcgg ctgcgggctt tgtcgaacat
     9481 atggcccacc agcagaccca ggaccacgcc ccaaaagccg ccgcccatca tcagggctac
     9541 ggcgacgcca attatctttc cccagtactg catagactcc ccaaaacgtt acgctatcgg
     9601 tgaggctatc tcccacaaaa taaggtgctt ttccgcgaat gaaggctacg gtcatttgtg
     9661 ggacatcgcc tataatttgc attatcatac ctgtcattca atgccgtgcc taacaccaca
     9721 gacgctaaac ggcaggatta acactggcgc agcgaagatg agtaagttag gctgtgaccg
     9781 tttgtcacgc gcaacgctac cgatgatgga acaataaata caacgtatga aaaaacgtat
     9841 tcccactctt ctggccacca tgatcgccag cgccctttat agtcatcagg ggctggcagc
     9901 cgatctcgcc tcacagtgta tgttgggcgt gccgagctac gatcgtcctc tggtaaaagg
     9961 cgataccaac gatctgccgg ttactatcaa tgccgataac gctaaaggta actacccgga
    10021 cgatgccgtt tttaccggca acgtggacat tatgcagggg aatagccgcc tgcaagcgga
    10081 tgaagtgcag cttcatcaga agcaggcgga aggtcagccg gaacctgtac gcaccgtcga
    10141 tgcgctgggt aatgtgcatt atgatgacaa tcaggtcatc cttaaagggc cgaagggctg
    10201 ggcgaacctg aacaccaaag acacgaacgt ctgggaaggc gattaccaaa tggtgggccg
    10261 tcaggggcgc ggtaaagccg atctcatgaa gcagcgtggc gaaaaccgct ataccattct
    10321 ggaaaacggc agctttacct cctgtctgcc tggctccgat acctggagcg tggtggggag
    10381 tgaagtcatc catgaccgtg aagaacaggt tgcggagatc tggaacgccc ggtttaaagt
    10441 aggtccggtt ccgatctttt atagccccta tttacagcta cccgtcggtg acaaacgtcg
    10501 ctcaggtttc ctgatcccga acgcgaaata cacgaccaag aactatttcg agttctactt
    10561 accgtattac tggaacatcg cgcccaatat ggacgccacc atcaccccgc actatatgca
    10621 ccgccgcggc aatattatgt gggagaacga attccgttat ctcacgcagg ccggcgccgg
    10681 gttgatggaa ttagattatc tgccttctga taaagtctac gaggacgaac atcccaaaga
    10741 gggcgataag caccgctggt tattctactg gcagcactca ggcgtgatgg atcaggtgtg
    10801 gcgttttaac gtcgattaca ccaaagtcag cgactccagc tactttaatg atttcgacag
    10861 taagtacggt tccagtaccg acggctacgc aacgcagaaa ttcagcgtcg gctacgccgt
    10921 acaaaacttt gacgctacgg tgtcgaccaa acaattccag gtctttaacg atcagaacac
    10981 cagcagctat tcagcggagc cgcagttaga cgttaactac taccataacg atctcggccc
    11041 gtttgatacc cggatttacg gtcaggcggt gcactttgtc aacaccaaag acaatatgcc
    11101 ggaagcgacc cgcgtccacc tggagccgac cattagtctg ccgctctcca accgctgggg
    11161 cagtctgaac accgaagcga agctgatggc gacgcactat cagcagacga atctggactg
    11221 gtacaacgcc aataacagca aaaaactgga agattcggtt aaccgcgtca tgccgcagtt
    11281 taaagtcgac ggtaagctcg tcttcgaacg cgatatggcg atgctggcgc cggggtatac
    11341 ccaaacgctg gaaccacgcg tgcagtacct gtatgtgccg taccgcgacc agagcggcat
    11401 ctataactac gattcttctt tgctgcaatc cgactataac ggcctgttcc gcgaccgcac
    11461 ttatggcggt ctcgaccgta ttgcttccgc caaccaggtc acgaccggcg tcacaacacg
    11521 catttatgat gatgccgccg ttgaacgttt taacgtttct gttggtcaaa tctactattt
    11581 cacggagtct cgcaccggcg atgacaacat taaatgggag aatgacgaca aaaccggttc
    11641 gctggtttgg gcaggtgaca cttactggcg tatttcagaa cgctgggggc tgcgtagcgg
    11701 agtgcagtac gatacccgtc tggatagcgt cgctaccagc agcagcagcc tcgaataccg
    11761 tcgggatcag gatcgtctgg tacagttgaa ctaccgctat gccagcccgg aatatattca
    11821 ggctacgttg ccttcgtatt attccacggc agagcagtat aaaaacggca tcaaccaggt
    11881 gggcgcggtg gcaagttggc cgattgccga tcgctggtcg attgtcggcg cgtactactt
    11941 cgataccaat tcgagcaaac ctgcagacca gatgctcggc ttgcagtaca actcttgctg
    12001 ctatgcgatc cgcgtcggat acgaacgtaa gctgaacggt tgggataacg ataaacaaca
    12061 cgcgatttat gataacgcga ttggcttcaa cattgagctg cgcggtttga gctctaacta
    12121 cggcctcggc acgcaagaaa tgttgcgttc gaacattctg ccgtaccaaa gctctatgta
    12181 atctgattga tttacaacgt aatccgcatt gcggttaatt gaaatggaaa aagtatgaag
    12241 aactggaaaa cgctgcttct cggtatcgcc atgatcgcga ataccagttt cgctgccccc
    12301 caggtagtcg ataaagtcgc agccgtcgtc aataatggcg tcgtgctgga aagcgacgtt
    12361 gatggcttaa tgcaatcagt caaactcaac gcgggtcagg caggtcagca gcttccggac
    12421 gacgccacgc tgcgccacca gatcctggaa cgtttgatta tggatcaaat tatcctgcag
    12481 atgggtcaga agatgggggt gaagatcacg gatgagcagt tggatcaggc catcgccaac
    12541 atcgccaaac aaaacaatat gacgatggat cagatgcgca gccgtctggc ttacgatggg
    12601 ctgaactatt caacctaccg taaccagatt cgtaaagaga tgattatctc tgaagtgcgc
    12661 aacaacgaag ttcgtcgccg tatcaccgtt ttgccgcaag aagttgacgc gctggcaaaa
    12721 cagattggca cccaaaacga cgccagcacc gagctgaacc tgagccatat cctgattgct
    12781 ctgccggaaa acccaacctc cgagcaggtt aacgacgcgc agcgccaggc ggaaagcatt
    12841 gttgaagaag cgcgtaacgg cgcagatttc ggcaaactgg cgattaccta ctctgccgac
    12901 cagcaggcgt taaaaggtgg tcagatgggc tggggccgta ttcaggagct gccggggatt
    12961 ttcgcccagg cgctgagcac cgcgaagaaa ggcgacattg tcggcccgat tcgctccggc
    13021 gtcggcttcc acattctgaa agtaaacgac ctgcgcggtc agagccagag tatctccgtg
    13081 accgaagttc acgctcgtca cattctgctt aagccgtcgc cgatcatgaa cgatcagcag
    13141 gcgcgcctga agctggaaga aatcgcggct gacattaaga gtggtaaaac cacatttgcc
    13201 gcagcggcga aagagtactc tcaggacccg ggctccgcta accaaggcgg tgatttgggt
    13261 tgggctacgc cagatatttt cgatccggcg ttccgcgacg cgctaacgaa gctgcataaa
    13321 ggccaaataa gcgcgccggt acactcctct ttcggctggc atctgatcga attgctggat
    13381 acgcgtaagg tagacaaaac cgatgcggcg cagaaagatc gcgcttatcg tatgctgatg
    13441 aaccgtaaat tctcagaaga agcggcgacc tggatgcaag aacagcgcgc cagcgcttac
    13501 gttaagattt tgagtaacta atgagcagtg cgcaacgcgt tgttatcact cccggcgaac
    13561 ccgccgggat tggccccgat cttgtcgtcc aactggcgca acgcgcgtgg ccgattgaac
    13621 tggtcgtctg tgcggacggc gcgctcctga cggagcgggc cgccatgctc ggcctgcccc
    13681 tctcgcttct cccttactcg cctgatgtcc ccgctgcgcc gcagcccgcg ggaacgctga
    13741 ccctattgcc ggtctcgctg cgcgcgcctg ccatccccgg tcagttgacg gtagaaaatg
    13801 gcccctacgt ggtagagacg ctggcgcgag cgtgtgatgg ctgtctgaac ggtgaatttg
    13861 ccgcgctgat cacaggcccc gtgcacaaag gcgttattaa cgacgcaggc attccgttta
    13921 ccggtcatac cgagtttttc gaagagcgtt cgcaggcgaa aaaagtcgtg atgatgctgg
    13981 caaccgaaga acttcgcgtg gcgctggcga ccacgcatct gccgctacgg gcgattgcag
    14041 acgccatcac ccctgcgctt ttgcacgaag tgattgctat tttgcatcac gatttgcgga
    14101 ccaaatttgg tattgccgaa ccgcgcattc ttgtctgtgg cctgaatccg cacgcgggcg
    14161 aaggcggtca tatgggcacg gaagagatag acaccatcat tccggtgctc gacgagctgc
    14221 gggcgcaggg gatgaaactc aacgggccgc tacctgctga tacgctgttt cagcccaaat
    14281 atctcgataa tgccgacgcg gtgctggcaa tgtaccacga tcagggcctg cccgtgctaa
    14341 aataccaggg attcggtcgg ggagtgaata ttacgctcgg cctacctttt attcgaacct
    14401 ccgttgatca cggcaccgcg cttgaactgg cgggccgagg aaaagcggat gtcggcagtt
    14461 ttattacggc gcttaatctc gccatcaaaa tgattgttaa tacccaatga ataatcgagt
    14521 ccatcagggc catttagccc gtaaacgctt cgggcaaaac tttctcaacg atcggtttgt
    14581 gatcgacagt attgtttctg ctattaatcc gcaaaaaggc caggcgatgg ttgaaatcgg
    14641 ccccggtctg gcggcgctga cggagccggt cggcgaacga ctggataagc tcacggtcat
    14701 tgaacttgac cgcgatctgg cggcgcgttt gcaaacccat ccgtttttag ggccgaagct
    14761 gactatttat cagcaggacg ccatgaccat gaactttggc gaactgtctg cgcagttggg
    14821 ccagccgctg cgtgtgttcg gcaatctgcc ctataatatc tccaccccgc tgatgttcca
    14881 tctctttagc tatactgatg ccattgccga catgcacttt atgttgcaaa aagaagtggt
    14941 aaatcgtctg gttgcagggc cgaacagcaa agcgtatggt cgtttaagcg tgatggcgca
    15001 atattactgt caggtgatcc cggtgcttga agtgccgcca tccgccttca cgccgccgcc
    15061 caaagtggac tccgccgtgg tgcgtctggt tccacacgca acgatgcctt acccggttaa
    15121 agatattcgc gtgttgagcc gtattaccac cgaggccttt aaccagcgcc gtaaaacgat
    15181 ccgtaatagt ctcggcaatc tttttagcgt tgagacgttg acggaaatgg gtattgaccc
    15241 ggcaatgcgc gcggaaaata tctctgtcgc gcagtactgc cagatggcca actatctgtc
    15301 ggaaaacgcg cctttgaagg agagttaaac atgatcaatt cgcccagagt gtgtattcag
    15361 gtgcaaagcg tctacattga ggcgcaatcc tcacctgacg atgaacgtta cgtttttgcc
    15421 tataccgtaa ccatccgcaa tctgggtcgg gcgccagtgc agctattggg ccgctactgg
    15481 ctgattacca atggtcatgg ccgtgaaact gaagtccagg gcaaaggtgt ggttggcgtc
    15541 cagccgcgca ttgcgcctgg cgaagagtat cagtacaccg gcggcgcggt aattgaaacg
    15601 ccgctgggca ccatgcaggg tcattacgaa atgatcgatg aaaatggcga cgcctttacc
    15661 atcgacattc ccgtgtttcg actcgccgtc cctacactca ttcactaaaa ttataacaat
    15721 ggcaacttat ctcatcggcg acgttcacgg ttgctacgac gaactgatcg ccttattaca
    15781 gcaagtggaa tttacgccag atacagacac tctatggctg actggcgatt tggtcgcccg
    15841 cggtcccggt tcgctggacg tgttacgcta cgtcaaatcg cttggcaata gcgtgcgttt
    15901 ggtgctgggg aatcacgatt tacacctgtt ggccgtattc gccgggatta gccgcaacaa
    15961 acctaaagac cggctgaccc cgcttcttga agcgccggac gccgatgagc tgttgaattg
    16021 gttacgccgt cagccgctgt tgcaggtaga tgaagagaaa aagctggtca tggcgcatgc
    16081 gggtattacc ccacagtggg atttgcagac ggcaaaagag tgcgcccgcg atgttgaagc
    16141 ggtgctgtcg agcgactcgt acccgttttt cctcgacgcg atgtatggcg atatgccgaa
    16201 taactggtcg ccggagttaa gcggtctggc gcggctacgc tttattacta atgcctttac
    16261 ccgtatgcgt tactgctttc ctaacggtca actggatatg tacagcaaag cgtcgccgga
    16321 aaatgcccct gcgccgctga agccgtggtt cgccattccg ggaccggtga gcgaggctta
    16381 cagtattgct ttcgggcact gggcgtcgct ggaagggaaa gggacgccag aaggtattta
    16441 cgcgctggat accggctgct gctggggcgg ggagttaacc tgtttacgtt gggaagataa
    16501 acagtatttt gtgcagccgt caaaccgcca gatggatatg ggcgaaggcg aagcggtcaa
    16561 cgcctgatag gtttatgcct gatggcgcta cgcttatcag gcctacatcc ggctcaagag
    16621 taggccggat aaggcatttc gccgccatcc ggcactacag cgttaacgac gctccagaat
    16681 ctcgaaacaa tagctgtgag aattctgcgc gtcggcatcg tgaaactcac tgaataccga
    16741 ttcccagtca tccggttcat aatccggaaa atgggtatcg ccttcgactt ccgcatcaat
    16801 atgcgtcaga taaagcttct gcgcctttgg caggaactgc tcgtacacgc gcccgccgcc
    16861 aatgaccata atttccggcg catcgccgca agcggcaatc gcctcatcga cagacttcac
    16921 ccactgcacg cgatcgtcgg tgcccggctg gctgctgata ataatatttt tacgtcccgg
    16981 taaggggcgt ccgatggact cccaggtgtg acgtcccatg acgacaggtt tatttaacgt
    17041 gttacgttta aaccatgcga gatcggcagg caggttccac ggcatggcgt tttccatacc
    17101 gatgacgcga tccaccgcta acgccgcaat cagactgatc attaattatt tcctgataca
    17161 aaaaaaattg ccgccactat acgtaaagcg caatctttcg tcgactgacg aaaagaggat
    17221 gagcacgaaa atttttcgtt ctgctggcga cgccactcat ttgatgtgga gcgccagcat
    17281 tacagtagtt caaaaacagc caattagcag taaagtttgc agaacatcac attttttact
    17341 ttagattgac ggtttgacct cgggttcatc agcggccttc ccggaatgtt tgccctcagc
    17401 cgttccctgc cagccgtggc gctgaatcaa cgacagatgc tcccggtcct cggtaataat
    17461 ttcgctcaac atcgcgctgg tacgtttata ggcggcggcg cgagataacg gatcgttttc
    17521 ccctttcgcc atctcttcca ccatccgggt attaaaatga cagaacagat ccgcgcgctc
    17581 gcgggcttca taacgcccca gccccagcgc ctccaaagcc tgtcgcccgc ttttgagcgc
    17641 gccttcgaag gtttcacgtt cgggcatcgc cacaccagcc tggcgcaggc gaatgtaatg
    17701 atcgacatca cgggcgcggg cgataatctg cagatgcggg aaatgcgtct tcaccagttc
    17761 actcagttgc aaattggttt gcggatcgtc aatggcgtta atcaatacct ccgccttcgc
    17821 cgctccggca gattccagca aatccatacg cgtcgcgtcg ccataaaaaa ccttcatgcc
    17881 gaatttacgc agcgtttcga tatgatcggg gtcgtgatcg agcaccacca tcttcacccc
    17941 gctcgacagc agtaaacgcc cggctatctg cccaaatcgc ccaaacccgg ccacaatgac
    18001 ccgcggctgc tcttcgtcga tttcatccgc ctcgcgcgct tcacccgttg cggtcttttc
    18061 catgcgcgtc agcagcacca gaaaaatcgg cgtggccgcc atcgacagcg cgaccgccag
    18121 cgtcagcgct tttgcccatt ccggctcaag tacatccgcc atttgcgccg cgccaaaaac
    18181 cacaaacgca aactcacttc cctggcctaa taagacggca aaccagcgac gctgttttgc
    18241 cggtacgccc agggtcctcg cgaccagcca cagcatgacg attttgattg ccagaaaacc
    18301 ggccaacaac agcagaatgc gcagcggatt ctccaccagc gtgccgaaat caatcgacat
    18361 gccgacgcca ataaagaaca accccagcag caacccctta aagggttcaa tatcgctttc
    18421 cagcgcatga cgatattccg aactcgccag cagaacgccc gccaggaacg cgcccatcgc
    18481 cattgacagc ccaacctctt ccagcaacag gccgaaacca aacaccagaa atagcgccac
    18541 ggcgctgaac acctcccgca aaccagaacg cgcgacaaag cgcagcgccg ggcgcgtaac
    18601 gtagcgtccc agcaacacca ccagcgccaa cgcgcctgcg actttcaacg ccgatagcgc
    18661 aaacgcgcca agcgtggtgg atgcgccgct ggcggccagc agaggaatca tcgccaccag
    18721 cgggatcgcc gcgatatcct ggaacaagag cactgcaaat gcgctacgcc ctacctgtga
    18781 aacggtcagg ttacgctcat tcattgcctg catggcgata gccgtggacg aaagcgccag
    18841 cgtcatgcca atcagttccg ccacctgcca acgcaggcca agaaacatac agaacagacc
    18901 aatcagtccg ccgcagacca ccatctgtaa cgcgccgccg ccaaataccg aggcgcgcag
    18961 cttccataac cgttgcgggt ccagttcaag cccaataaca aacaacatca gcacgacgcc
    19021 gatttccgca aaatgcagaa tagattcggc gtccgtcacc agccgtagcc cccaggggcc
    19081 gataatgcaa cccgcaatca gataccccag cactgatcct aagcccaaac gtaccgcaat
    19141 cggcacaatc aacgccgctg aaccaagata gatcagcgcc tgcagtagag tatggctatc
    19201 catgattcac ctcctgccat gccagtaaac gctgtttata ctgacgcgcc tgcgcctgta
    19261 aggtgtcgtc atcgcaaatg aacgtgcagt gcatggcaaa cggcggcagc catttgaggc
    19321 cgcaatagag cgccgtcgcc tgtagcggct gagaaaggac ggcaaatcct ggatgggagc
    19381 cgatagcaaa gtggttttca ccaccgccgg tcgttaccgc ccacagcaga tgtttaccat
    19441 gcaatgccgt accgccatga ccgtaagccc agccgtgggt gaggacttta tccatccata
    19501 atttgagtaa aggagggacg ctgtaccact gcatcggatg ctgccagacg ataagactcg
    19561 cgcgcgacag cgcctcttgc tcggcggcta cgtcaatatt gaaatcggga tagaggtgat
    19621 aaagcgaacg tatttcgacg ttttccagcg tccctgcctg ttcaagcatc tgcttattcg
    19681 catgagaatg atgcggatac ggatgcgcat aaataatgag gatcatgatt agcctgtgat
    19741 gatctgtttt ttatcacaaa gtgtagtgac aaattcgcca ggctaatagt gaatattatt
    19801 gagcggctaa tcagaaaaaa ttgaattaac gccagcaagg agttgacgcc atcctgcccc
    19861 cggaagatgc cctcgaaggg ccgcaggcgt ttgtggaaaa gcgcgatccg gtgtggaaag
    19921 gttggtgatg atggcagcct taaattgctg acaaatcggt ttaaggcctt cttgtcgggt
    19981 ggcgctgcgc taaattttcc tgtaatgact gtaatatcaa tccattacat gatgacacag
    20041 gcccaataag cgcagcgcca acagcatctg aacctccaga cacgctggat gctagatcac
    20101 cgacgcataa attaacctaa tgggtcaggc tcttaatctt tcgccatgcg gttaaattgc
    20161 tcaatagtaa gatcccatgg ctcacgggcc gcatccggca taaaactgcc gtcatccacg
    20221 ccaatttcgt ctttgataat tttattcagt ttttcattca tcgtaagaat gagatcctga
    20281 tatttctgtt tatcagcagc aaggttatgg ttctcatcag gatcattttt aagatcgtaa
    20341 agttcaagat cgttgtactt aataagatcc tcccaggttt ccggcgtatt atgctccctt
    20401 agcgagaaat agcgtgcaaa cttataacgg ccatcgttaa tcatccgcgt ccctgaacga
    20461 tggctgaaat caggatgcaa atgcgatatt tcctgcttga tttgcgccac cgtttttgtt
    20521 tatctctttg tagcgcgata acacggtgga gataatgggc atcggtatac aagatcatgc
    20581 catagcaata taagctggca tttctcaccg cattaaccgc aacgctctcc gggtttttta
    20641 gcaatccgct aaaattaacg cctttgcggt tgcctaacgc ctggtgctgt ttttcttccg
    20701 gcaaaccggt cagcccaact aatgtcggcg caatatcaag atgacaggtc aacgcctgac
    20761 atttcttatt accggggtac gccgggtggg aaataatcat cggtacatgg atctgttctt
    20821 tataaacgga agcgccttta ccgtgcatct gatggcttcc gcctaattcg ccatgatcgg
    20881 cagtaaatac aacaatcgtt ttatcagtta acttgagggc atccagttca tttaatatcc
    20941 ggtcaaggtg agtatcacaa tcgcggatac agttgaaata gtagtcaagc agtttacgcc
    21001 aacgacgatc ttcatcagga aactgccctt ccagcgcagc gcgcgccgtc tggtattcaa
    21061 gatgcgccgg cggtcttccc tgctcattga atgattgatg cctgtttgcc ggcagcggat
    21121 agttcggcca gcttgcctga taaagctcgt tttccggcgg ctgcgtgggc gccagggtat
    21181 tatcatcctg atccaactcg ccacgccact gtaccttttc tccttcttta tcggtatcaa
    21241 taaacatgac gtcatgagga ttaacgaggt taacggccag gaaccagggc ttgtgttggt
    21301 cattcaaggg ctgccccttg catcttaacc aatttatagt ctgagccgtg gtggttgaat
    21361 cataaaaata gccgccttta ctatggccta taatatcgcc gatgccgtga tagtcagcaa
    21421 aaccatattt ttccataatt ttatgtaatt ctggttcagg aatatccccg acatcaatat
    21481 cctcatcttt ttcgtcaggc aaaggcttct ccagtttttc tgtaagatgc cacttacctt
    21541 tataggccgt atagtatccc agttcccgca tcatatggcc tgtggttcca agagcggggt
    21601 caaggtcata aggcatccag ggtaatccca gattatcaaa catctttgtc tggggcatat
    21661 gtaagccggt atacaatacg gagcgggaag gcgtacagac attactggta ttctgatgat
    21721 tacagaatgt cacccccgtt ttcatgagcc gctctctgcc gggtacaggg aaaggaaacg
    21781 taggaaaaaa acgctcctag tcggtcacga ctaacagaat attatatcct tctggcaatt
    21841 tttccgggat ttcgccagta aacggtttat cccacgtcgg tttcgccttg acggcgcatt
    21901 tttcatcagc ctttaccgcg ccggatagca taccgccggc ggcaagaata ccggcgctgg
    21961 ttaacagttt cctacgcgta agatccgtct cttctgcgga cagatt
//
LOCUS       DAJVKX010000072        21448 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.072, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000072 DAJVKX010000000
VERSION     DAJVKX010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 21448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21448
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.072"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            11..1063
                     /gene="pipB2"
                     /locus_tag="OPY25_002762"
     CDS             11..1063
                     /gene="pipB2"
                     /locus_tag="OPY25_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector PipB2"
                     /protein_id="HCS0928342.1"
                     /translation="MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCG
                     GIRRRNETQYQELIETMAETLKSSMSDRGAPLPENIILDDVDGCRVEFNLPGENNEAG
                     QVIVRVSKGDNSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
                     GANLTAENLCDADLSGADLEGAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSI
                     MCGATLDRANLTGANLQHTSLLGCSMVECNCSGANMDHANVSGSTLIRADMSGATLKG
                     ATIMAAIMEGAVLTRANLQKASFTATNLDGADLSEANLRNTSFKDCTLTDLRTEDATM
                     STSTQTLFNVFYSENI"
     gene            1238..1571
                     /locus_tag="OPY25_002763"
                     /pseudo
     CDS             1238..1571
                     /locus_tag="OPY25_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2085..4265
                     /locus_tag="OPY25_002764"
     CDS             2085..4265
                     /locus_tag="OPY25_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461704.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HCS0928343.1"
                     /translation="MGMRVKKFIWLITVVSTGINSPLSAAESTDDNGETIVVESTAEQ
                     VLKQQPGVSIITRDDIQKNPPVNDLADIIRKMPGVNLTSNSASGTRGNNRQIDIRGMG
                     PENTLVLIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEMIRGPAAARYGSG
                     AAGGVVNIITKRPTNDWHGSLSLYTNYPESSKEGDTRRGNFSLSGPLAGDTLTMRLYG
                     NLNRTDADSWDINSSAGTKNAAGREGVTNKDINSVFSWKMTPQQILDFEAGYSRQGNI
                     YAGDTQNSNSNAVTKSLAQSGRETNRLYRQNYGLTHNGIWGWGQSRLGFYYEKTDNTR
                     MNEGLSGGGEGRITNDQTFTTNRLTSYRTSGEVNVPVIWLFEQTLTVGAEWNRDELND
                     PSSTSLTVKDSNIAGIPGSAANRSSKNKSEISALYVEDNIEPMAGTNIIPGLRFDYLS
                     ESGSNFSPSLNLSQELGEFVKVKAGIARAFKAPNLYQTSEGYLLYSKGNGCPKDITSG
                     GCYLVGNKNLDPEISINKEIGLEFTVDDYHASVTYFRNDYQNKIVAGDQIIGRSASGA
                     YVLQWQNGGKALIEGIEASMAVPLMPDRLNWNTNATYMITSEQKDTGNPLSIIPKYTV
                     NTFLDWTITNALSANVNWTLYGKQKPRTHAESRSEETKGLSGKALGAYSLVGANVNYD
                     INKNLRLNVGISNIFDKQIYRSAEGANTYNEPGRAYYAGVTASF"
     gene            complement(4325..5242)
                     /locus_tag="OPY25_002765"
     CDS             complement(4325..5242)
                     /locus_tag="OPY25_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCS0928344.1"
                     /translation="MYGRQYHNKCYRVALFLVSFCFSALSYAQPDMQPLGPNMADKGS
                     GYYHFRVNDFQSADGARHYRVWTAIPNKAAPPSGYPVLYMLDGNAVMDRLPETLLKQL
                     ADHSPPVIVAIGYQTNLPFDLNGRAYDYTPAPGIDRDDSENNPRFHRKTGGGPAFRQL
                     LERHIAPQVEQGITINPERRGIWGHSYGGLFVLDSWLSSSFFHIYYSASPSLSRDNFA
                     LLNRLTAVKPSPFCHKKLIIMEGSASNGDSRQRQMAELLQKVQETVRTLENNGVNAAL
                     QHYPGLGHGPMFNASFRSALLGISREPAS"
     gene            complement(5274..6518)
                     /locus_tag="OPY25_002766"
     CDS             complement(5274..6518)
                     /locus_tag="OPY25_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCS0928345.1"
                     /translation="MRLSPPVAPVAIQTATRLRRQLAAGSQVDASHFWREANSLALPL
                     VTAINGADDEREVTFLWRAASPLRGVYVRLNRVTDKDNVAKGMMTQLPTTDIWHLTLR
                     LPASYCGSYTMVEIPPKTPDETVLQLGSRFASLVGKADPLNSTPGINVRGNAQESVLA
                     LDHAPAQEEWSGCRAYAGQLFTSEHRLAGQRRRVRLYLPDVPVEQPLGLLVLTDGEIW
                     FDHLGVSAAIDAAIRSGRIAPVAVLGVDNINARERVAILGGRRELVLDIAERLLPTLR
                     AKYPERQWADRTQTVLAGQSLGGVTALMAARHAPESFGLVLSHSPSMWWTPDNRNRPP
                     HFSAEERSWVSEHVLSAPSPAVRTHLCVGSLEGSTVPQVKQLHEKLRAAGVESHCCVY
                     TGGHDYAWWRGALIDGLRLLPR"
     gene            complement(6628..10284)
                     /gene="iroC"
                     /locus_tag="OPY25_002767"
     CDS             complement(6628..10284)
                     /gene="iroC"
                     /locus_tag="OPY25_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="salmochelin/enterobactin export ABC transporter
                     IroC"
                     /protein_id="HCS0928346.1"
                     /translation="MPATHSPMPARAWIVRLARVCWERKTLSIIVIVASVSTILLAAL
                     TPLITRQAVNDAIAGDTTRLPLLACGLLLIALFDFIGNYVRRGYAGELSLWVQHTLRS
                     RAFDSIQKLDGAGQDALRTGQVISRTNSDLQQVHTLLQMCPVPLAVLTYYVAGIAVML
                     WMSPSMTLIVICVLAALAITALRARRRVFAQTGLASDRLAHMTEHMREVLEQISVVKS
                     CVAELRETRWLDGQSRQMVRVRIGAAISQAMPGATMLALPVIGQIVLLCYGGWSVMNG
                     RIDLGTFVAFASFLAMLTGPTRVLASFLVIAQRTQASVERVFALIDTRSRMEDGTESV
                     EGQIIGLDVEKMSFHYDNGNRILNEISFSIHAGETVAVVGASGSGKSTLLMLLARFYD
                     PTSGGVWLNTTTGQQNIRDLKLTALRRRVGVVFEDAFLFAGTVAENIAYGHPQATQDD
                     IRRAADAAGASGFINALPQGFNTRLTERGSNLSGGQRQRIALARALITAPELLILDDT
                     TSAVDAGTEAEINTALGRYADNEHMLLVIARRRSTLQLADRIVVLDKGRVVDIGTQAE
                     LDARCPTFRSLMSGEGDFLALAPAEQRTLWPTTQAVKSDDAHERQTTAGKGFVDRMTR
                     VPERAVQMALAGHGSQVSSLLTPVAWMFVIAALLIALDSAAGVGVLVLLQRGIDSGVA
                     AGDMSTIGICALLALCLVAIGWCCYALQTIFAARAAESVQHTVRLRSFSHLLRLSLPW
                     HEKHIDSRLTRMTVDVDSLARFLQNGLASAATSIVTMVAIAAAMFWLDPILALTALSA
                     VPVVILATWIYRRLSSPAYAQARLEIGKVNSTLQEKVSGMRVVQSHGQQKQEAARLRA
                     LSDNFRATRVRAQKYLAVYFPFLTFCTEAAYAAVLLIGATRVAEGEMTPGILAAFFLL
                     LGQFYGPVQQLSGIVDSWQQATASGKHINALLATEETENIEPSSITPGTGGALRLEAL
                     TFRYPEKTQPVLDNLSLTIPPGTVVAVVGRSGAGKSTLIKLLAGLYSPGSGQIRVGER
                     LIDAASLSDYRRQTGLVTQDVALFSGDIAENIRYSRPDSSDTEVEIAARQAGLFETVQ
                     HLPLGFRTPVNNGGTDLSAGQRQLIALARAQLAQAHILLLDEATARIDRSAEERLITS
                     LTGVTHTEKRIALIVAHRLTTARRCDVIVVIDKGCIAEYGSHEQLIAAHGLYARLWRA
                     SVGQTRDTQGEVVG"
     gene            complement(10365..11480)
                     /gene="iroB"
                     /locus_tag="OPY25_002768"
     CDS             complement(10365..11480)
                     /gene="iroB"
                     /locus_tag="OPY25_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="salmochelin biosynthesis C-glycosyltransferase
                     IroB"
                     /protein_id="HCS0928347.1"
                     /translation="MRILFVGPPLYGLLYPVLSLAQAFRVNGHEVLIASGGKFAQKAA
                     EAGLVVFDAAPGFDSEAGYRRQEALRKENNIGTKMGNFSFFSEEMTDPLVAFAGQWRP
                     DLIVYPPLGVVGPLIAAKYDIPVVMQTVGFGHTPWHIKGVTKSLSNAYRRHGVSAPPR
                     DLAWIDVTPPSMSILQNDGEPVISMQYVPYNGGAVWEEWWERTPDRKRLLVSLGTVKP
                     MVDGLDLISWVMDSASEVDAEIILHLPANARSDLRSLPPNVRLVDWLPMGIFLNGADG
                     FIHHGGAGNTLTALHAGIPQIVFGQGADRPVNARAVVERGCGIIPGKSGLTSSMINTF
                     LGNRALRETSQEVAAEMAAQPCPTEVAKKLIAMLQHG"
     gene            12164..12730
                     /locus_tag="OPY25_002769"
     CDS             12164..12730
                     /locus_tag="OPY25_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016529756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCS0928348.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALNCAGCERIFEDKISGTKSDRPG
                     LKKLLRTLSAGDTLVVWKLDRLGRSMRHLVTLIEELRQRGVNFRSLTDSIDTSTPMGR
                     FFFHVMGALAEMERELIVERTRAGLAAARAKGRVGGRRPKLTSEQWAQIGRLLEAGES
                     RQRIALIFDVGVSTIYRKFPANKNNKSP"
     gene            12873..14045
                     /locus_tag="OPY25_002770"
     CDS             12873..14045
                     /locus_tag="OPY25_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HCS0928349.1"
                     /translation="MAQDYHHGVRVVEVNEGTRSITTVSTAIVGMVCTGDDADAKMFP
                     LNKPVLITDVLTASGKAGESGTLARSLDAIADQAKPVTVVVRVPQGETEEETTTNIIG
                     AVTAEGKKTGMKALLSAQSQLGVKPRILGVPGHDTKAVATELLSVAQSLRGFAYLSAY
                     GCKTVQEAITYRENFSQREGMLIWPDFTGWDTVLNAEATAYATARALGLRAKIDEQTG
                     WHKSLSNVGVNGVTGISADVFWDLQDPATDAGLLNQNDVTTLVRKDGFRFWGSRCLSD
                     DPLFAFENYTRTAQVLTDTMAEAHMWAVDKPLNPSLARDIIEGIRAKMRSLVSQGYLI
                     GGDCWLDESVNDKDTLKAGKLTIDYDYTPVPPLENLMLRQRITDQYLVNFSSQVSA"
     gene            14055..14570
                     /locus_tag="OPY25_002771"
     CDS             14055..14570
                     /locus_tag="OPY25_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HCS0928350.1"
                     /translation="MALPRKLKHLNLFNDGNNWQGIVESLTLPKFTRKYEKYRGGGMP
                     GAVDVDLGLDDGALDTEFSIGGTELLLFKQMGKATVDGIQLRFTGSIQRDDTGEVQAV
                     ELVVRGRHKEVDSGEWKTGESNTTKVTSTNSYAKLTINGEVLYEVDLINMVEIVDGVD
                     LMEAHRNALGL"
     gene            14625..14927
                     /locus_tag="OPY25_002772"
     CDS             14625..14927
                     /locus_tag="OPY25_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HCS0928351.1"
                     /translation="MSDKKTEKTIQLDTPIKRGKTEITEIVLRKPQSGALRGTRLQAI
                     MDMDVNAMMTVIPRISSPALTAQEIAEMDPADLTAMSVEVVTFLLKKSVLAGLPTA"
     gene            14942..15061
                     /locus_tag="OPY25_002773"
     CDS             14942..15061
                     /locus_tag="OPY25_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HCS0928352.1"
                     /translation="MADIATIFHWPPSVTDVMPLTEVLEWRYKAIQRSGANDE"
     gene            15054..18131
                     /locus_tag="OPY25_002774"
     CDS             15054..18131
                     /locus_tag="OPY25_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCS0928353.1"
                     /translation="MSDNNLRLQVILNAVDKLTRPFRSAQASSRELAAAVKKSRDAIK
                     QLDQAGSSLDSFRKLQAENQKLGDRLNYARQRANLLSQELGAMGPPSQRQVVALGRQR
                     LAVQRLEERQKKLQQQTALVRAELYRAGISAKDDAGATARLARETSRYNQELSKQEAR
                     LKRLGEAQRRMNVARASYARSLEVRDRIAGAGATTTAAGLAMGTPVMAAVKSYTSMED
                     AMKGVAKQVNGLRDDNGNRTARFYEMQDAIKAASEQLPMENGAVDFAALVEGGARMNV
                     ANPDDSWEDQKRDLLAFASTAAKAATAFELPADELSESLGKIAQLYKIPTRNIEQLGD
                     ALNYLDDNAMSKGADIIDVMQRLGGVADRLDYRKAAALGSTFLTLGAAPEVAASAANA
                     MVRELSIATMQSKSFFEGMNLLKLNPEVIEKQMTKDAMGTIQRVLEKVNALPQDKRLS
                     AMTMLFGKEFGDDAAKLANNLPELQRQLKLTAGNDALGSMQKESDINKDSLSAQWLLV
                     KTGAQNTFSSLGETLRQPLMDILYMVKSVTGASRRWVEANPELTGTLMKVAAVVAAVT
                     VGLGTLAVALAAVLGPLAVIRLGFSVLGIKTLPSVTAAVTRTSSALSWLAGAPLALLR
                     RGLASSGNAAGLLTAPLSSLRRTASLTGNVLKTVAGAPVALLRSGLSGLRAVAVMFMN
                     PLAALRGGLAAAGAVLRVLASGPLAMLRIALYAVSGLLGALLSPIGLVVTALAGVALV
                     VWKYWQPITAFLGGVVEGFKAAAGPISAAFEPLKPVFQWIGDKVQALWGWFTDLLTPV
                     KSTSAELQSAAAMGRRFGEALAEGLNMVMHPLDSLKSGVSWLLEKLGIVSKEAAKAKL
                     PESVTRQQPATVNADGKVMMPSGGFPSWGYGFAGMYDSGGYIPRGQFGIVGENGPEIV
                     NGPANVTSRRNTAALAAVVAGMMGVAAAPAELPPLHPLAFPAKGGEAMVSRAATVSPV
                     QRIEAPTQIIIQTQPGQSVQDIAREVARQLDERERRLKAKARSNYSDQGGYDA"
     gene            18128..18613
                     /locus_tag="OPY25_002775"
     CDS             18128..18613
                     /locus_tag="OPY25_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0928354.1"
                     /translation="MMMVLGLYVFMLRTVPYQELLYQRSWRHAANSRVNRRPSTQFLG
                     PDNDMLTLSGVLMPEITGGRLSLLALEQMAEQGKAWPLIEGSGTIYGMYVIEGLNQTK
                     TEFFRDGMPRRIEFTLSLKRVDESLSDMFGDLSAQLNNLQDTVTSALSDISKTVGGLL
                     S"
     gene            18610..19710
                     /locus_tag="OPY25_002776"
     CDS             18610..19710
                     /locus_tag="OPY25_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HCS0928355.1"
                     /translation="MNFSSELLNKGNKTPAFSISIEGKDITTVLDNRLMSLTLTDNRG
                     FEADQLDLELDDADGKIVLPRRGAVITLALGWKGQPLFPKGAFTVDEIEHTGAPDRLT
                     IRARSADFRETLNTRREKSWHKTTVGEVVKEIAARHKLKMALGEDLSDKPVEHIDQTN
                     ESDGSFLMRLARQYGAIASVKNGNLLFIRQGQGKSASGKPLPVITITRKDGDSHRFTL
                     ADRGAYTGVIASWLHTREPAKKESTTVKRKRRTKKQKKEPEAKQGDYLVGTDENVLVL
                     NRTYANRSNAERAAKMQWERLQRGVASFSLQLAEGRADLYTEMPVKVSGFKQPIDDAE
                     WTITTLTHTVSPDNGFTTSLELEVRIDDFEME"
     gene            19801..20019
                     /locus_tag="OPY25_002777"
     CDS             19801..20019
                     /locus_tag="OPY25_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001504085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HCS0928356.1"
                     /translation="MMICPLCGSAAHTRSSFQVSSLTKERYNQCQNINCSHTFVTHET
                     FVRSIATPKESNPVQPHPMKSGQVALSL"
     gene            20109..21431
                     /locus_tag="OPY25_002778"
                     /pseudo
     CDS             20109..21431
                     /locus_tag="OPY25_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
BASE COUNT         5186 a         5511 c         6032 g         4719 t
ORIGIN      
        1 gagaaaatat atgcagcgtt cactcgatag tctggctggt atggctacat ctgcttttgg
       61 cgcggggact tctgctgcta tgcggcaagc tacctcgccc aaaaccattc tgcaacatat
      121 cattaacttt tttacctgtg gtgggatacg tcggagaaat gaaacacaat atcaggaatt
      181 gatagagact atggctgaaa cattgaaaag ttcaatgtct gacagaggtg ctccgttgcc
      241 agaaaacatc atcctggatg atgtggatgg gtgtcgtgtc gaatttaatc ttcctggtga
      301 gaataacgaa gctggacaag ttattgtacg agtcagtaaa ggcgacaatt ctgagacaag
      361 agaaattccg cttgcctctt ttgaaaaaat atgtcgagct ttactattca gatgcgaatt
      421 ttctcttcct caggattctg taatattaac tgcccaggga ggcatgaatc ttaaaggcgc
      481 tgtccttacc ggagcaaatc tgacggcaga aaatttatgt gacgcagact taagcggcgc
      541 agatttagag ggggcaatac tgtttatggc ggattgtgac ggtgcaaatt ttaagggcgc
      601 aaatctatcg ggagcatcat taggcgacag taacttaacg aacgcctgtc tggaagatag
      661 tattatgtgt ggcgctaccc tcgatcgcgc taatcttact ggcgccaatt tacaacacac
      721 aagtctgtta ggctgtagca tggtagaatg taattgttcc ggtgcgaata tggatcacgc
      781 taatgtttca ggctcaaccc ttatacgtgc cgatatgagc ggtgcgacat taaagggtgc
      841 tactataatg gctgctatta tggaaggcgc tgtcttaact cgggcaaacc tgcaaaaggc
      901 tagttttact gctacgaacc tggacggggc tgatttgtct gaggctaatt taagaaatac
      961 cagttttaaa gattgtacac taaccgattt gcgtaccgaa gacgccacaa tgtctacaag
     1021 tacacaaaca ctttttaacg tattttatag tgaaaatatt tagccctatt tgacgtaaat
     1081 ctgaaataaa agcaatgtaa gaataacaat ctgctactga atagtagctg agagttaatt
     1141 atttacagta tcttttatta ttacaggagt atgcgccggt aaaaatatct gaataaccat
     1201 ttctattttc tcaagtagaa cttccaacta aagcgaattg tttgaaaagg aaaacgttat
     1261 gcctggatgt ataagtgcct gttcgtgcgt tgccagcccg acgcctcccg atcctaaggc
     1321 ccccccctaa gcctaagtgg atagagttaa aaggttattg tgttacatgt actagtcagg
     1381 aggatattcg tccacctaaa gagggtgaac caaagcaaaa aatgacaccc agcgagttag
     1441 tgctgttacg aggtctttta aaagacctgg gggtaacaca acatccctgg caagacccga
     1501 cagtaaaatc cactaactgt gggttgccat attttccagt agatcctgga gaacgagaaa
     1561 ccgatgtttg atggttttct gtctgcaaag cgcctgataa ttattaccag gcgctttgta
     1621 ttttggcgcc aacatcactt tcattgtcat atatcgaatg actacaatcg tatccgatcc
     1681 cgccattacc ctgacggcaa actgtaagaa cggtttgccg tcgacaggga agcgccggtg
     1741 aactctgaac cgcactatac catcttacct gggtgtttat tatcattaac gctttgaaaa
     1801 atagttttat tttatctatt cctgttttgt aaaacctccg ctcagtaggc gcattctgcc
     1861 acccttcccg gatttattgg caaagcggag cccggacaga gagtcatatt gcaaaatccc
     1921 gtttctgttt tcttatgacc agattttgcg gtcgaaagat tgcctttttc ttaattgaat
     1981 gataattatt atcattagca tatgataata attactatat agccgtaacc tggcaaggat
     2041 gtgagcttga gggcaacagc gctactttag acattattta gggaatgggt atgagagtta
     2101 agaagttcat ctggttaata accgtggttt ctacagggat taatagtcca ttatcagcag
     2161 cagaatctac agacgacaac ggcgaaacga tagtggttga atccactgcc gagcaagtat
     2221 taaagcaaca gccgggcgtt tcgattatta ctcgtgacga tattcagaag aatcctcccg
     2281 ttaacgatct tgccgatatt attcgtaaga tgcctggggt taatcttacc agcaatagcg
     2341 cctcggggac gcgcggaaat aaccgacaaa ttgatattcg tggtatgggg ccggaaaata
     2401 ccttagtgct gattgacggc gtgccggtga cgtcgcgaaa ttcggttcgc tatagctggc
     2461 gcggagaacg cgacacccgt ggcgatacga actgggtgcc gccggagatg gtagaacgta
     2521 ttgaaatgat ccgtgggccc gccgccgcgc gctatggctc cggtgccgca ggcggggtgg
     2581 tgaacatcat caccaaacgc cccactaacg actggcatgg ctcgctgtcg ctttatacca
     2641 actacccgga aagcagcaaa gaaggtgaca cccggcgggg taactttagc cttagcggcc
     2701 cgttggctgg tgatacgttg acgatgcgcc tgtacggtaa tctcaacaga accgatgccg
     2761 acagctggga tattaactcc tccgccggta ccaaaaatgc cgccggacgg gagggggtca
     2821 ccaataaaga tattaatagc gtcttctcat ggaaaatgac cccgcagcaa atccttgatt
     2881 ttgaagcggg atacagtcgg caggggaata tctatgccgg cgatacgcaa aacagtaatt
     2941 caaacgcggt taccaaaagt ctggcgcagt ccgggcggga gaccaatcgc ctgtaccggc
     3001 agaattacgg tctaactcat aacggcatct ggggctgggg gcaaagccgc ctggggttct
     3061 actatgaaaa aaccgataat acccgcatga atgagggact ctccggcggc ggcgaggggc
     3121 gtattaccaa cgaccagacg ttcaccacta accgcctgac ctcgtatcgc accagcggcg
     3181 aggtgaatgt cccggtgata tggctatttg agcaaacgct caccgtcggc gcggagtgga
     3241 accgcgatga gctgaacgat ccttcctcta ccagtctgac ggttaaggat agcaatatcg
     3301 ccgggattcc cggttcggcg gctaaccgta gcagtaaaaa taaatcggaa atcagtgcgc
     3361 tgtacgttga agataatatc gaacccatgg ccggtaccaa tattattccg ggtctgcgtt
     3421 ttgactattt gagcgaatcc gggagtaatt ttagtcccag tcttaacctt tcccaggagt
     3481 taggtgaatt cgtcaaggtg aaagccggta ttgcccgggc ctttaaggca ccgaacttgt
     3541 atcaaaccag tgaggggtat ttactctatt cgaaaggcaa cggttgtcca aaagatatta
     3601 cgtcgggcgg ctgttacctg gttggtaata agaacctcga tcctgaaatt agtatcaata
     3661 aagagattgg gctggaattt accgtagacg attatcacgc aagcgtaacg tatttccgta
     3721 acgattatca gaataagatt gtcgcaggtg atcagattat tggcagaagc gcatctggcg
     3781 cttatgtatt gcagtggcag aacggcggta aagcgctgat tgaaggtatt gaagccagca
     3841 tggctgttcc gctgatgccg gaccgtctga actggaatac caatgcgact tatatgatca
     3901 cttctgagca aaaagatacc ggtaatccct tatcgataat cccgaaatat acggtgaata
     3961 ccttcctcga ctggactatc accaacgcgc tctccgctaa cgtcaactgg acgttatacg
     4021 gcaagcaaaa accgcgaaca catgcggagt cgcgtagtga agagaccaaa ggattgtccg
     4081 ggaaagcgct gggggcttac tcactggtcg gcgctaacgt taactacgat atcaataaga
     4141 acctgcgtct taatgtcggt atcagcaata tcttcgataa acagatctat cgctccgccg
     4201 aaggggcaaa tacctataac gaaccgggtc gggcttatta tgccggtgtg acggcctcgt
     4261 tttgatgggt tatgcccgcc gctggcgggc atattctggc gacgggttaa tggcagcgtg
     4321 gttcttagct tgccggttcg cgactgatac ccagcaatgc actacgaaaa gaggcgttaa
     4381 acatgggccc gtggcccagg cccgggtaat gctgcagggc cgcgttaacg ccgttgttct
     4441 caagcgttct cacggtctcc tgaacttttt gcaggagctc ggccatctgg cgttgcctgc
     4501 tatccccatt cgacgctgaa ccttccatta tgatgagttt tttatggcag aacggcgacg
     4561 gcttcactgc cgtaaggcga ttcaacaggg caaagttatc cctgctgagt gacgggctgg
     4621 cgctgtaata gatatgaaag aaggatgacg acagccagga gtccaaaacg aacaggccgc
     4681 cataagaatg tccccatatc ccgcgccgtt cggggttgat ggttattcct tgttccacct
     4741 gcggcgcgat atgtctctcc agtagctggc ggaacgctgg cccgccgccg gtcttacgat
     4801 gaaaacgcgg gttattttca ctgtcatcgc gatcgattcc cggcgccggc gtatagtcat
     4861 aagctctgcc gttaagatca aacggcaggt tagtctgata gccaatcgcc acaatcaccg
     4921 gcggcgagtg gtctgccagt tgtttgagca gcgtctccgg cagcctgtcc atcactgcgt
     4981 tgccgtccag catatataag acaggataac ccgacggcgg ggcggcttta ttgggaatag
     5041 cggtccatac ccggtaatgt cttgcgccat cggcagattg aaagtcattg accctaaaat
     5101 ggtaatatcc cgaaccttta tcagccatat tcggccctaa tggctgcata tccggctgcg
     5161 cataactcag cgcgctaaaa caaaaactca ctaaaaatag cgccacgcga tagcacttgt
     5221 tgtggtactg gcgaccatac atcggatgtt attccttttt ggcaggtgaa gttttatcgg
     5281 ggcagtagac gtaatccgtc aatcagcgcg ccgcgccacc aggcataatc gtgaccgccg
     5341 gtgtacacgc agcaatggct ttcaacaccg gcggcgcgca atttttcatg caactgtttg
     5401 acctgcggga ccgtcgaacc ttccagcgat cccacgcaca gatgcgtacg tacggctggc
     5461 gagggcgcgg ataacacatg ttcgctgacc catgagcgct cttctgcgct gaaatggggc
     5521 gggcgattgc ggttgtccgg cgtccaccac attgaggggg agtggctcag caccaggccg
     5581 aagctctctg gcgcgtggcg ggccgccatc agcgcggtca cgccgccgag gctttgccct
     5641 gccagcaccg tttgtgtacg gtccgcccac tgtcgttccg ggtatttggc gcgaagggtt
     5701 ggcagcaggc gttcggcaat gtcgagcacc agctcgcggc gaccgccgag gattgcgacg
     5761 cgttcacgcg cattgatatt atcaacgccg agtacggcca ccggcgcgat gcgtccgctg
     5821 cggatggcgg cgtcaatggc ggcgcttacc ccaagatggt cgaaccagat ctcgccatcc
     5881 gtgagtacca gcaagcccag cggttgttcg acaggaacgt caggaagata cagccgcaca
     5941 cggcgacgtt gtccggcgag ccgatgttct gaggtgaaaa gctgcccggc gtaagcgcga
     6001 cagcctgacc actcctcctg tgccggggca tgatccaacg ccagaacgga ctcctgcgca
     6061 ttgccccgaa catttattcc cggcgtgctg ttcagtgggt ccgccttccc gacaagggag
     6121 gcgaaacggc ttccaagctg caacaccgtc tcgtccgggg ttttcggtgg tatttcgacc
     6181 atcgtatagg aaccgcagta ggacgccggt aagcgaagcg tcagatgcca gatatccgtt
     6241 gtgggcagtt gcgtcatcat acctttcgcc acgttatctt tatcggtgac acggttcagg
     6301 cgaacataaa ccccccgcag aggagaggcg gcacgccaca ggaaggtgac ttcccgttca
     6361 tcgtctgcgc cgttaatggc tgtcaccagc ggcagcgcga gcgagtttgc ttctcgccag
     6421 aagtgagaag cgtcaacctg gcttccggcg gcgagttgac ggcgaaggcg cgtagcggtc
     6481 tgtatagcga caggagcgac gggcgggctc agtctcattc tttgtattcc atctcgttta
     6541 tatttcggtc agtatcaata gctaaagcgg ctgttacagg aacagccgct tgcgggcttt
     6601 cttttgcgta aatcgtggcg ataaaaacta tcctacgacc tctccttgcg tatcgcgtgt
     6661 ctggccgacg ctggcccgcc acagacgagc atacaggcca tgagccgcta tcaactgctc
     6721 atggctgcca tattcagcga tacatccttt atcgattacg acaataacat cgcagcggcg
     6781 agcggtggtc agtcggtgcg cgacgataag cgcgatgcgt ttctcggtat gcgtcactcc
     6841 ggtaagcgag gttattaagc gctcctcggc gctgcggtcg atacgtgctg tcgcctcgtc
     6901 gagcagcaga atgtgcgcct gtgccagttg ggcgcgcgcg agggcaatca actgacgctg
     6961 gcccgcggac agatccgtgc cgccgttatt gaccggagta cgaaacccca gcggcagatg
     7021 ttgcacagtt tcaaagagtc ccgcctgtcg cgccgcgatc tccacctccg tgtcgctgct
     7081 gtctggccgc gaatagcgga tattttcggc aatatcgccg ctaaataatg cgacatcctg
     7141 ggtgaccagc cccgtctggc gacgataatc actaagcgac gcggcatcaa ttaggcgctc
     7201 accgacacgg atttgcccgc tgccgggaga gtagagcccg gccagcagct tgatcagcgt
     7261 cgatttgccg gcgccgctac gtccgaccac cgcgactacc gttcctggcg gaatggtgag
     7321 cgagagatta tcaagcacag gttgcgtttt ttcgggatag cggaatgtca atgcctccag
     7381 acgtagcgcg ccgccagtgc caggcgttat ggaggacggt tcaatattct ccgtttcctc
     7441 agtcgccaat agcgcattga tatgtttgcc gctggcggtc gcctgctgcc aggaatcaac
     7501 aatgcctgac aactgctgta ccgggccata aaattgtccc aatagcagga agaacgccgc
     7561 cagtatcccg ggcgtcattt cgccttcggc gacccgggtc gctccgatta aaagcacggc
     7621 ggcataggca gcctcggtgc agaaggtcag gaacggaaaa tagacagcaa ggtatttttg
     7681 cgcccgcacg cgggtggcgc ggaagttgtc tgataacgcc cgtagcctgg cggcttcctg
     7741 cttctgttga ccgtgtgact gcactacccg cataccggag accttttcct gaagcgtact
     7801 gttcacctta ccaatttcca gccgtgcctg ggcgtaagca ggcgagctca aacggcggta
     7861 aatccacgtc gccagtatca ctacaggtac ggcgcttaat gccgttaacg caagaatggg
     7921 gtcaagccag aacattgccg cggcgatagc gaccatcgtc acgatgctgg tggccgcgct
     7981 ggcaagaccg ttttgcagaa atcgggcgag tgaatcaacg tcgacggtca tgcgagtaag
     8041 acgcgagtcg atgtgcttct cgtgccaggg aagactcagg cgtagcaggt ggctgaagct
     8101 gcgtaagcgt accgtatgct gtaccgactc tgccgcgcgg gcggcgaaga tcgtttgcag
     8161 cgcatagcag caccaaccga tcgccaccag gcacagcgcg agcagggcgc atatgccaat
     8221 agtcgacata tcccctgcgg caacgcctga gtcaataccg cgctgcaaaa gcaccagcac
     8281 gccaacgcct gcggcggaat caagcgcgat aagcagggcg gcgatgacga acatccaggc
     8341 tactggcgtc agcagcgatg agacttgact cccgtggcct gccagcgcca tctgtacggc
     8401 gcgttccgga acgcgcgtca tccggtcgac aaaacctttt ccggcggttg tctggcgctc
     8461 atgcgcgtcg tcggatttta ccgcctgcgt tgttggccat agcgtacgtt gttctgccgg
     8521 ggcaagggcg agaaaatccc cctcgccgct catcagcgag cgaaacgtcg gacaccttgc
     8581 atccagctcc gcctgggtac cgatatccac gacgcggcct ttatccagca cgacgatccg
     8641 atcggctaac tgcagtgttg aacggcggcg tgcaatcacc agcagcatat gctcattatc
     8701 ggcataacga ccaagagccg tgttaatttc cgcttcagta ccggcatcga ccgccgaggt
     8761 ggtgtcatcg agaatcagca gttccggcgc ggtaatcagt gcccgggcta gcgcaatacg
     8821 ctggcgttgg ccgccggaga ggttgcttcc gcgttcggtc agtcgggtgt tgaacccctg
     8881 cggtagcgca ttgatgaacc cgctggcgcc tgcggcatcg gcggcgcgtc gaatgtcgtc
     8941 ctgagtcgct tgcgggtgcc cataggcgat gttttccgcc accgtaccgg caaacagaaa
     9001 cgcgtcttca aaaactacgc caacgcgacg acgaagcgcc gtcagtttca ggtcgcgaat
     9061 attctgttga cccgtagtgg tgttgagcca tactccgccg gaggtgggat cgtaaaagcg
     9121 cgccagcaac atcagcaatg ttgatttccc ggagccggat gcgccaacca ccgccacggt
     9181 ttcaccggcg tgaatggaaa acgagatctc attgaggata cggttaccgt tgtcgtagtg
     9241 gaaactcatc ttctccacgt ccagcccgat aatctgaccc tcaaccgact cagtaccgtc
     9301 ttccatgcga gaacgcgtgt cgataagcgc gaagacgcgc tctaccgacg cctgtgtgcg
     9361 ctgtgcgata accaaaaacg atgccagtac gcgggtaggg ccggtcaaca tagcgagaaa
     9421 actcgcgaac gctacgaagg ttcccagatc gatgcgcccg ttcatcaccg accagccgcc
     9481 atagcacagc aggacgatct gccctatcac cggtagcgcc agcatggttg cgcccggcat
     9541 cgcctgcgag atagcggcac cgatccgtac ccgcaccatc tgccgcgact gaccatcgag
     9601 ccaacgcgtt tcgcgtaact ccgccacgca ggacttcacc actgagatct gttccaatac
     9661 ttcgcgcata tgttccgtca tgtgcgccag ccggtctgag gcaagccccg tttgcgcgaa
     9721 aacacggcga cgggcgcgca gggcggtaat agcaagggcg gccagtacgc aaatcacgat
     9781 aagcgtcatg gatggcgaca tccatagcat caccgcgata ccggccacat agtaagtgag
     9841 caccgccagc ggcaccggac acatctgtag caaggtgtgt acctgttgaa gatcgctgtt
     9901 ggtacgcgaa atgacctgcc cggtacgcaa ggcgtcctgg cctgcgccgt ccagtttttg
     9961 aatactgtcg aacgcacggc tacgtaacgt atgctgaacc cacaacgaga gttctccggc
    10021 atagccgcgg cgcacgtaat tcccgataaa atcaaaaagg gcaattaaca gcaggccgca
    10081 ggcaagtaac ggcaggcggg tcgtatcgcc tgctatcgcg tcattgacgg cctgacgcgt
    10141 tattagcggc gtcagcgcag ccagtaaaat ggtcgatact gatgctacga tgacaatgat
    10201 gctcagtgtt ttacgttccc aacacacgcg ggcaaggcga actatccagg cacgagcggg
    10261 catgggggaa tgagtcgcgg gcattaagcc tccttatcgg tgaaagatga gttatggcga
    10321 cacagtctgg gctcagccgc catattgtca ttgcgctgcc gcggttagcc gtgttgcagc
    10381 atggcgatca gtttttttgc cacctcggtc gggcaaggct gggccgccat ttccgccgcg
    10441 acttcctgcg acgtctcgcg aagcgcgcga ttaccgagaa aggtattgat catgctgctc
    10501 gtaagtccgc tcttaccggg aataatgccg catccgcgct cgaccacggc gcgggcattg
    10561 acaggtctgt cggcaccctg gccaaagact atctgcggaa tgccggcatg cagcgccgtc
    10621 agagtgttgc ctgcgccgcc atggtggata aaaccgtcgg cgccgttaag gaaaatgccc
    10681 atcggaagcc agtcgaccag acggacattc ggcggcagag aacgtaaatc cgagcgggcg
    10741 tttgccggaa gatgcagaat gatttcggca tctacttcgc tggcagaatc cattacccag
    10801 gaaatcagat ccaggccatc caccatcggt ttgacggtgc cgaggctaac cagaagacgc
    10861 ttgcgatcag gtgtacgttc ccaccattct tcccagacgg cgccgccgtt atacgggacg
    10921 tattgcatgg agataaccgg ctctccgtca ttttgcagta tgctcatgct gggcggtgtg
    10981 acgtctatcc acgccagatc tcttggtggc gcgctgaccc catggcggcg gtaggcgtta
    11041 gaaagtgatt tcgtcacgcc tttgatgtgc cagggcgtat gaccgaagcc gacggtttgc
    11101 attactaccg gaatgtcata cttagcggca atcagtggtc caacgacccc aaggggagga
    11161 tagacgatga gatctggccg ccactgtccg gcgaacgcga ccagcgggtc ggtcatctct
    11221 tcgctgaaaa atgagaagtt ccccattttt gttccaatgt tattttcttt tcgcaatgcc
    11281 tcctgacggc gataacccgc ttccgaatcg aaaccaggcg cagcgtcaaa taccaccaac
    11341 ccagcttctg ctgctttctg tgcaaatttt ccaccgcttg caatcagcac ttcatggcca
    11401 ttaacacgaa acgcttgcgc cagggacagc acagggtata gcagtccata cagtggtgga
    11461 ccgacaaaca gaatacgcat gagaaatcct ctctctccac gtcataaatc gaataagtcg
    11521 ttaatgagaa tgataataat taccaatatc atttgaaaaa tgcaataata aatacgaccc
    11581 ttgatcatgt gatgattttt tgcgtaaaaa tcggggaaga ggagagcgtt aagcggtgaa
    11641 gtttggtttc aggcttattt acgcgcgtat ggtcgagaag gcaaaacgcc aggattgggg
    11701 aactggattc gcataccaga cgcccgtgga ttattaatga taacttcgca aataaccttt
    11761 cagacaatgc ggtaaacgta ccgacagcaa ggtaacggga aacgcaggga gtagtattga
    11821 taacacgttg cggggcaatt taatggtgtc cggcggcaga tcgtgtctgt gcagactttc
    11881 cggcgttaaa tcccgtatca cctgcgaacc tggactatct ctgtggtatc aactctgtag
    11941 taattttgtc cccttcgtct tcattagcca atgaaaccgg ctttaacgtc accgttcgaa
    12001 tgttgcgaac gaacagctcc ttatgcggac tatcgtcacc gctctgcgat ttttatagcg
    12061 caccagccac acgatttatt ggttcttgaa aaccaacgtt tatgaaaatg cagaggtaac
    12121 agctaactgg catcatctcc ggtttttatt caggggaatg atcatgctta ttggctatgt
    12181 acgcgtgtca acaaatgacc agaataccga tttgcaacgc aatgcactga actgcgcggg
    12241 atgtgagcgg atttttgagg acaaaatcag tggcaccaag tccgacagac cggggctgaa
    12301 aaagctgctc aggacactat cggcaggaga cacgctggtt gtctggaagc tggacagact
    12361 ggggcgcagt atgcggcatc ttgttacgct gatagaagag ctgcgccagc gtggcgtgaa
    12421 tttccgaagc ctgactgaca gtattgatac cagcacccca atgggccgtt tcttttttca
    12481 tgtcatgggt gccctggctg aaatggaacg cgaactgata gttgaacgta ccagggcggg
    12541 gctggctgca gctcgtgcta aaggcagagt aggtggacgc cgtcctaagt tgaccagcga
    12601 acagtgggca cagattgggc gtttactcga ggccggagaa tcaagacagc gtattgcact
    12661 gatttttgat gtaggcgttt ctaccattta tcgaaaattt ccggcaaata agaacaataa
    12721 atctccctga atcagcatta ttttgattat tcctgcaagc ggacaaatac cgtcattttg
    12781 tgtgaataac ggtacaactg cgcttagctg tttgtcggac acaatcactt caacataggg
    12841 cgaagcctaa tccaatcagg aggttcgcca ctatggctca ggattaccac cacggggtgc
    12901 gcgttgttga agtcaacgaa ggcacccgat ccattaccac ggtgagcacc gccatcgtgg
    12961 gtatggtctg cacgggcgat gatgccgatg caaaaatgtt tcctcttaat aaacccgtgc
    13021 tgatcactga tgtgctgact gccagcggta aagcgggtga gtcaggcacg ctggcccgtt
    13081 cgctggatgc catcgctgac caggcaaaac ccgtgaccgt tgttgtgcgt gtgccgcagg
    13141 gtgaaacgga agaagaaacc acgaccaata tcatcggcgc agtgaccgct gaaggtaaaa
    13201 aaacaggcat gaaagccctg ttatctgccc agtcacagct tggcgttaaa ccgcgcattc
    13261 tcggcgtgcc aggccacgac accaaggcgg tagctactga gttgctgagc gtggcgcaaa
    13321 gcctgcgtgg atttgcttac ctgtcagcgt atggctgcaa gacggtacag gaggcgatca
    13381 cttaccgtga aaacttcagc cagcgcgaag ggatgctgat ctggcctgac tttactggct
    13441 gggacactgt gctgaatgcc gaagcaacgg catatgccac cgcccgtgcg cttggtctgc
    13501 gcgccaaaat tgacgagcag accggatggc acaaaagcct gtccaacgtg ggcgtgaacg
    13561 gtgtcaccgg aatttctgct gatgtgttct gggatctgca ggacccggca accgatgcgg
    13621 gactgctgaa ccagaacgac gtcaccacgc ttgtgcgtaa agacggtttc cgcttctggg
    13681 gttcccgctg cctgagtgat gacccgctct ttgccttcga aaactacacc cgcacggcgc
    13741 aggtgctgac ggacacgatg gcagaagcgc acatgtgggc ggtggataaa ccgctgaatc
    13801 cgtcgctggc ccgcgacatt atcgagggta tccgcgccaa aatgcgcagc ctggtcagtc
    13861 agggctatct cattggtggt gattgctggc tggatgagtc ggtgaacgac aaagacacgc
    13921 tgaaagccgg aaaactcacc atcgactacg actacacgcc agtgccgcca cttgaaaacc
    13981 tgatgctgcg tcagcgcatc accgatcagt acctggtgaa tttctccagc caggtcagcg
    14041 cgtaagggga caacatggct ttaccacgca aattaaaaca cctgaacctg tttaatgacg
    14101 ggaacaactg gcaggggatc gttgagtcgc tgacgctgcc gaaatttacc cgcaaatatg
    14161 agaagtatcg cggcggcgga atgccgggtg cagtggatgt ggatctgggg ctggatgacg
    14221 gcgcactgga tacggaattt tccattggtg gtactgagct gctgctgttt aagcagatgg
    14281 gcaaagccac ggtggatggc atccagctgc gctttaccgg ctctattcag cgtgatgata
    14341 ccggggaagt gcaggccgtg gagcttgtgg tgcgtggacg tcacaaagaa gtggattccg
    14401 gcgagtggaa gacgggcgaa agcaacacca ccaaagtgac cagtaccaac agctacgcga
    14461 agctgaccat caatggtgag gtgctctatg aagtggacct gatcaacatg gtggaaattg
    14521 tggacggtgt ggacctgatg gaagcgcacc gtaacgccct cggcctctga tgtatctgaa
    14581 cggcgtggga taccgcgcca gaacccaatt tacaggacag caaaatgagc gataagaaga
    14641 ctgaaaagac cattcaactg gatactccca tcaagcgcgg aaaaacggaa atcaccgaaa
    14701 ttgtgctgcg taaaccgcag tccggtgcgc tgcgcggtac acgcctgcag gccattatgg
    14761 atatggatgt gaacgcgatg atgaccgtga tcccccgcat ctccagcccg gcactgactg
    14821 cacaggaaat tgcagagatg gacccggcag atctcactgc catgtcggtt gaggttgtca
    14881 cttttttgtt gaagaagtcg gtgcttgccg gtttaccgac agcctgacgg ttgacgatct
    14941 ggtggcagat atcgccacca tttttcactg gccgccatcc gttactgacg ttatgccgct
    15001 gaccgaagtg ctggaatggc ggtataaagc gattcagaga agcggggcca acgatgagtg
    15061 ataacaacct gcgtctgcag gtcattctta atgcggttga caagctcacc cgcccatttc
    15121 gatctgcgca ggccagttca agagaactgg ctgctgctgt caaaaaatcc cgcgatgcaa
    15181 taaagcagct tgatcaggcc gggagcagtc tggacagctt ccgaaagctg caggcagaaa
    15241 atcagaaatt aggcgacagg ctgaactatg cccgccagcg tgcaaatttg ctcagtcagg
    15301 aactgggagc gatggggccg ccttcgcaac gtcaggttgt tgctctgggc cgtcaacggc
    15361 tggctgttca gcgcctggaa gaacgccaga aaaagctgca gcagcagacg gcgcttgtgc
    15421 gtgctgaact gtaccgggcg ggaatttctg cgaaagatga tgcgggagca actgcccgtt
    15481 tagcccgtga aacatcacgt tataaccagg aactgtcgaa acaggaggcg cggctgaagc
    15541 gactggggga agctcagcgc aggatgaatg tggcgcgtgc cagttatgcc cgttcgctgg
    15601 aggtgcgcga tcgcatcgca ggagccggag ccaccaccac ggcggcaggg ctggcaatgg
    15661 ggacgccagt gatggcggca gtaaaaagct ataccagcat ggaagatgcc atgaaaggtg
    15721 tggcaaagca ggtcaatggt ctgcgtgacg ataatggcaa ccgcactgca cgtttttatg
    15781 aaatgcagga tgccatcaag gctgccagcg aacagttgcc gatggaaaac ggtgcggtag
    15841 acttcgctgc actggttgaa ggtggtgcgc gcatgaacgt cgcaaaccct gacgacagct
    15901 gggaagacca gaaacgtgac ctgctggcct tcgccagtac ggcagcaaag gcggcaacag
    15961 cctttgagct gccagcggat gaactgtcag aaagtctggg gaaaatcgcc cagctctaca
    16021 aaatccctac ccgcaatatt gaacagctcg gtgatgcgct gaactatctg gatgataacg
    16081 ccatgtcgaa aggggcagac attattgatg tcatgcaacg tctgggcggt gtggctgacc
    16141 gtctggatta tcgtaaagcg gcggcgctgg gttccacctt tctgacactg ggcgctgcgc
    16201 cggaggttgc agccagtgca gcaaacgcga tggtgcgtga attgtccatt gccaccatgc
    16261 aaagcaagag tttctttgaa gggatgaatc tgctgaaact caatcctgaa gttattgaaa
    16321 agcagatgac gaaggatgcg atgggaacta tccagcgtgt gctggagaag gtgaacgcac
    16381 tgccgcagga caagcgtctg tctgccatga ccatgttgtt tggtaaagag tttggcgatg
    16441 acgcggcgaa actggcaaac aacctgccgg aactgcagcg ccagctaaaa ctgacagcgg
    16501 gcaatgatgc gctcggctcc atgcagaaag aatccgacat taacaaggac tcactttctg
    16561 cgcagtggtt gctggtcaaa accggagcgc agaacacctt cagcagcctg ggcgaaacgc
    16621 tgcgccagcc gctgatggat attctgtaca tggtgaaaag cgtcacggga gcatcgcgtc
    16681 gttgggtgga agctaacccg gaactgacgg gcacactgat gaaagtagcc gctgtggtgg
    16741 ctgccgttac cgtgggcctc ggcaccttag cggtggcgct ggctgcagtg ctggggccgc
    16801 tggcagtcat ccgtctgggg ttctctgtgc tgggtatcaa aacgttacct tccgttacgg
    16861 cagcagtaac ccgaactagc agcgcgttgt cctggctggc tggcgcacca ctggcactgc
    16921 tgcgacgcgg gcttgcttca tcgggcaacg ctgcgggttt acttactgcg ccgttgtcgt
    16981 ctttgcgccg cacggcatca ctgacgggga atgtcctgaa aactgtagca ggtgcgccgg
    17041 ttgcactttt gcggtctgga ttatccggtt tacgtgctgt tgctgtgatg tttatgaatc
    17101 cactggcagc actacgcggt gggctggctg ccgcaggcgc ggtgctgcgt gtgctcgcat
    17161 ccggcccgct ggcgatgttg cgcattgccc tgtatgccgt atctggtctg ttaggtgctc
    17221 tgctcagtcc gataggtctt gtggttactg cactggcggg cgtggcgctg gttgtctgga
    17281 aatactggca acccatcacc gcatttctcg gtggcgtggt ggaaggattc aaagcggcgg
    17341 caggtcccat cagtgcagca ttcgaaccac ttaagcctgt gtttcagtgg attggcgaca
    17401 aagtgcaggc gttgtggggc tggtttactg atctgctgac gcccgttaag tcgacctctg
    17461 ccgaactgca gagcgcagcg gcaatggggc gacgattcgg ggaggcactg gcggaagggc
    17521 tgaatatggt catgcatccg ctggactccc tgaaatccgg cgtttcctgg ttgctggaga
    17581 aactcggtat tgtcagtaaa gaggctgcaa aggcgaaact gccggaaagc gtgacgcgtc
    17641 agcaacctgc gacggtgaat gcagacggta aagtgatgat gccatcaggt ggtttcccat
    17701 catggggata tggttttgcg gggatgtatg acagcggtgg gtatatcccg cgcgggcagt
    17761 ttggcattgt cggtgaaaac gggcctgaaa ttgtcaacgg cccggcaaac gtgaccagcc
    17821 ggagaaatac agctgcactg gctgccgttg ttgccggaat gatgggtgtt gctgccgcgc
    17881 cagcagagct tccaccgttg caccctttgg catttcccgc gaaaggcggt gaagcgatgg
    17941 tgagtcgcgc agccactgtg tcgcccgttc aacggattga ggcaccgacg cagatcatca
    18001 ttcagacgca gccaggacaa agtgtgcagg atattgcgcg ggaggtggcc cgccagcttg
    18061 atgaacgtga acgcaggctg aaggcaaaag ccaggagtaa ctacagcgat caggggggat
    18121 acgacgcatg atgatggtgc tgggattgta cgtgtttatg ctgcgcactg tgccgtatca
    18181 ggaactgctg tatcaacgca gctggcgaca tgcggcaaac agccgggtca accgacgtcc
    18241 atccacgcag tttctgggac cggacaacga catgctgacg ctttctggtg ttcttatgcc
    18301 ggagataacg ggcggcagac tgtcgttgct ggctctggag cagatggcag aacagggaaa
    18361 agcatggccc ctgattgaag gcagcggcac gatttacggc atgtatgtga ttgagggact
    18421 gaatcagact aaaacggagt ttttccgcga tggtatgccg cgccggattg agttcaccct
    18481 gtcgctcaaa cgggtggatg aatccctgtc cgatatgttc ggtgatctca gtgcgcagct
    18541 gaataatttg caggatacgg taacgtctgc cttaagcgat atcagtaaaa cggtgggagg
    18601 gctgctgtcg tgaatttcag ctctgaactg cttaacaaag gcaacaaaac tcccgcattc
    18661 agcatcagta ttgaggggaa ggatatcacc actgtgctgg ataaccgcct gatgagtctg
    18721 acgctgacgg acaatcgggg ctttgaagca gaccagcttg atttggagct ggacgacgcc
    18781 gacggaaaaa tcgtgctgcc gcgccgtggg gctgtcatta cgctggcgtt gggctggaag
    18841 gggcagccgc ttttcccgaa aggagcattc acggtggacg agattgaaca cactggcgca
    18901 ccggaccgcc tgactatccg ggcgcgaagt gctgattttc gtgaaaccct gaatacccgc
    18961 cgtgaaaaat cgtggcacaa gaccaccgtt ggggaagtgg tgaaggaaat agctgcgcgg
    19021 cacaaactga agatggcatt gggtgaagac ctgtcggata aacccgtgga gcatatagac
    19081 cagaccaatg agagtgacgg cagttttctg atgcggctgg cgcgccagta cggtgctatt
    19141 gcgtcggtga aaaatggcaa tctgttattc atccggcagg gacagggtaa aagcgccagc
    19201 ggtaaaccac tgccggtgat cactatcaca cggaaggacg gcgacagtca ccgctttacc
    19261 ctggcagatc gcggagccta cacgggcgta attgccagct ggttgcatac ccgcgaaccc
    19321 gcgaagaaag aaagcaccac ggtgaagcgt aagcgcagga ctaagaagca gaagaaagag
    19381 ccggaagcga agcagggcga ttacctggtg gggacggatg aaaacgtgct ggtacttaat
    19441 cgcacttatg ccaaccggag caacgccgaa cgagcggcga aaatgcagtg ggaacgcttg
    19501 caacgcggcg ttgcgtcatt ctcgctacaa ctggcggaag gtcgggcaga tctctacacg
    19561 gaaatgcctg tgaaggtcag tggctttaaa cagccgatag atgatgcgga atggaccatt
    19621 accaccctga cacatactgt cagcccggat aatggtttta cgaccagtct ggagcttgaa
    19681 gtgaggattg atgatttcga aatggaatga ttcttcgcaa tggagaactt ttaagtttgc
    19741 aaaatggaat aatgcggtat cattattgtg aatttagcaa aaatggggag agctcgaaaa
    19801 atgatgattt gcccactgtg tggaagtgcc gcccatactc gcagcagttt tcaggtatct
    19861 tcattgacca aagagcgtta caaccagtgc cagaacatta actgcagcca tacttttgtt
    19921 acccatgaaa cttttgttcg ttcgattgca acgccaaaag agtcaaatcc ggttcagccg
    19981 catccaatga aatcaggaca ggtggcgctc tctctttgac gctgccgcca ttttgtcgcc
    20041 atcgttaaaa aacagtgttt ctaacatcat gattttaaac agcttaaatt tcaggcaaca
    20101 aaaaacccat taaccttgct ccagccgatc taccgaaaga gggcggaagg tatgacctgc
    20161 ctattgctgt tgcgcttctg gccgcgtctg agcagcttac agcgtcgaat cttgaggcat
    20221 atgagctggt gggtgagtta gcgcttacag gcgcattacg cggcgttcct ggcgcaatat
    20281 caagtgcaac ggaagccatc agggccggca gaaatattat cgtcgcaaca gagaacacgg
    20341 cggaggttgg gcttatcagc aaagaaggat gttttatcgc cgatcatcta caaaccgtct
    20401 gcgcctttct ggaagggaaa cacgccctgg aaagaccttt agctcaggat atggcatcgt
    20461 ctaccgcaac tgccgatctt cgcgatgtga tcggtcagga gcagggtaaa cgcggcctgg
    20521 agattacagc ggcaggggga cataatctgc tattgatcgg cccgccgggt acgggtaaaa
    20581 ccatgctggc cagtcgactg agcgggattc ttccaccatt aagcaatgaa gaggcgttgg
    20641 aaagcgccgc gatcctcagt ctggttaatg ccgatacggt acaaaaacga tggcagcaac
    20701 gtccctttcg ctcacctcat catagcacct cacttactgc tatggtcggc ggcggcgcaa
    20761 tacccgcccc gggagagata tcgctggcgc acaacggaat tttgttcctt gatgaattgc
    20821 ctgaatttga acgacgcaca ctggatgcgc tacgtgaacc tatagaatcc ggtcaaattc
    20881 atttatcccg taccagagcg aaaataacgt accctgccag gttccagtta atcgccgcaa
    20941 tgaatcccag cccgaccgga cattatcagg gaaaccataa tcgctgcacg ccagaacaga
    21001 cactacgtta ccttaatcgg ttgtcaggcc cgtttcttga tcgttttgac ctttcgcttg
    21061 agataccgct tcctccgccc gggattctta gccaacacgc ctcaaagggt gagagcagcg
    21121 ctacggtaaa aaagcgggtc atcgccgccc ataaacggca gtaccgacgc cagaagaagt
    21181 taaacgcgcg tctggagggt cgcgaaatcc aaaaatattg tgttttacat cacgatgacg
    21241 cccgctggct tgaagacacg ctggtgcatc ttggattatc cattcgcgcc tggcagcgtt
    21301 tactaaaagt tgccagaacc attgccgaca tagaactggc tgaccagatc tcgcgtcagc
    21361 atttgcagga ggcggtaagc tatcgggcga tagacaggtt gttaattcat ttgcaaaagc
    21421 tgttggcgta aaaaaagggc attacgcc
//
LOCUS       DAJVKX010000073        21316 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.073, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000073 DAJVKX010000000
VERSION     DAJVKX010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 21316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21316
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.073"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..852
                     /gene="pocR"
                     /locus_tag="OPY25_002779"
     CDS             <1..852
                     /gene="pocR"
                     /locus_tag="OPY25_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein PocR"
                     /protein_id="HCS0928357.1"
                     /translation="ATTGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSD
                     RCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNV
                     DDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVENCLKKQLNFVVIKDNPQQSEA
                     NKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFN
                     AWVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINE
                     NSHPPSI"
     regulatory      1178..1353
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            1473..2828
                     /locus_tag="OPY25_002780"
     CDS             1473..2828
                     /locus_tag="OPY25_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HCS0928358.1"
                     /translation="MLAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPDYLDTGWH
                     TAICGVASRNLDSFMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNYCSTAA
                     MAKQLGCPVILLVDGKAVSTSLAAIVMGFQHFDPTLNLAGVIVNRVTSDAHYQLLKNA
                     IEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDALL
                     SLSLLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSP
                     LHDRALPDCQMIWLGGGYPELYAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGS
                     TLEDSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLAVPGEIVRGHEFHYSD
                     FIPETPAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRV
                     L"
     gene            2825..3784
                     /locus_tag="OPY25_002781"
     CDS             2825..3784
                     /locus_tag="OPY25_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HCS0928359.1"
                     /translation="MTILAWCIAWVLDFIIGDPQHWPHPVRWIGRLITFVQRIVRRYC
                     PGDKALRIGGGVMWVVVVGVTWGVAWGVLALAQRIHPWFGWSVEVWMIFTTLAGRSLA
                     RAAQEVERPLRENDLAESRIKLSWIVGRDTSQLQPAQIYRAVVETVAENTVDGIIAPL
                     FFLFLGGAPLAMAYKAVNTLDSMVGYKHEKYRAIGMVSARMDDVANYLPARLSWLLLG
                     IAAGLCRLSGWRALRIGWRDRYNHSSPNCAWSEACVAGALGIQLGGPNNYFGERVDKP
                     WIGDAQRGISVDDISRTIRLMWVASTLALALFIAARCGLSGVA"
     gene            3795..4274
                     /locus_tag="OPY25_002782"
     CDS             3795..4274
                     /locus_tag="OPY25_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-8X methylmutase"
                     /protein_id="HCS0928360.1"
                     /translation="MHYIQQPQTIEANSFTIISDIIRETRPDYRFASPLHEAIIKRVI
                     HTTADFDWLDILWFSADALEQLCDALRQPCIIYTDTTMALSGINKRLLATFGGECRCY
                     ISDPRVVGVPVGFVGAAESKEALTHSHFPAVAALGRKGGSNVAAAIVNALLYHLREA"
     gene            4274..5413
                     /locus_tag="OPY25_002783"
     CDS             4274..5413
                     /locus_tag="OPY25_002783"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HCS0928361.1"
                     /translation="MSELSFDAPVWRHGKALRKGYTTGSCATAAAKVAELMVLRQHLI
                     HQVSIVTPSGVTLCLNVESPHIEGQQAIAAIRKDGGDDVDATHGMLIFARVTLNDSGE
                     ITLTGGEGIGTVTRKGVGLPLGSAAINRTPRHTIESAVREAIGPARGADVEIFAPEGE
                     VRAQKTYNSRLGILGGISIIGTTGIVTPMSEESWKRSLSLELEIKRASGLTRVILVPG
                     NHGERFVREQMGVDTQAVVTMSNFVGYMIEEAVRLGFCQIVLVGHPGKLIKIAAGIFH
                     THSHIADARMETLVAHLALLGAPLELLTLVGDCDTTEAAMEHIEAYGFGHIYNHLARR
                     ICLRVMQMLRFTKTPPVCDAILFSFDNHILGSNRPVDEIAKELQC"
     gene            5407..6012
                     /locus_tag="OPY25_002784"
     CDS             5407..6012
                     /locus_tag="OPY25_002784"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HCS0928362.1"
                     /translation="MLTVVGMGPAGRHLMTPAALEAIDHADALAGGKRHLAQFPAFGG
                     ERFTLGADIGALLSWIAARRDKGIVVLASGDPLFYGIGTRLVAHFGIEQVRIIPGISA
                     VQYLCAQAGIDMNDMWLTSSHGRCVSFEQLANHRKVAMVTDARCGPREIARELVARGK
                     GHRLMVIGENLAMENERIHWLPVSAVNADYEMNAVVILDER"
     gene            6002..6580
                     /locus_tag="OPY25_002785"
     CDS             6002..6580
                     /locus_tag="OPY25_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HCS0928363.1"
                     /translation="MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGS
                     VSIEAALQFPSLQVTAIKRNPAALRLLDENRQRFACGNIDILPGEAPMTITGKADAVF
                     MGGSGGHLTALIDWAMGHLHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLS
                     SLTPLGAGHYFKPNNPVFVIACQKEENHVRDI"
     gene            6564..7337
                     /locus_tag="OPY25_002786"
     CDS             6564..7337
                     /locus_tag="OPY25_002786"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HCS0928364.1"
                     /translation="MSETFDPRCVWFVGAGPGDRELITLKGYRLLQQAQVVIYAGSLI
                     NTELLDYCPAQAERYDSAELHLEQIIELMAAGVKAGKTVVRLQTGDVSLYGSVREQGE
                     ELTRRGIDWQVVPGVSAFLGAAAELGVEYTVPEVSQSLIITRLEGRTPVPAREQLEAF
                     ASHQTSMAIYLSVQRIHRVAERLIAGGYPATTPVAVIYKATWPESQTVRGTLADISDK
                     VRDAGIRKTALILVGNFLGKEYHYSRLYAADFSHEYRKA"
     gene            7318..8373
                     /gene="cbiG"
                     /locus_tag="OPY25_002787"
     CDS             7318..8373
                     /gene="cbiG"
                     /locus_tag="OPY25_002787"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HCS0928365.1"
                     /translation="MNTVKPESIALFCLTPGGVALAKRLAAMLPLTCFTSEKLREEGF
                     IPFDGGFANTARQAFTTYTALIFIGATGIAVRVLAPLVNDKFSDPAVVVIDERGQHVI
                     SLLSGHAGGANALTRYLAGMLGADPVITTATDVNEMSALDTLAFQLNARMSDLRTAVK
                     TVNQMLVSHQRVGLWWDAELTEEIGQCDIRGFIPVDDLQRLPELDALICVSLRNDLPE
                     LPVLHWKLVPQRVVAGIGCRRDTPFPLLATLLARQLEAQKLDPLALKAIGSVTLKKGE
                     PGLIQLASCCRVPFKTFTAEALREFEHHFPGSGFVRKTVGVGSVSGPAAWLLSQGQLL
                     GETLREQGVTITLGVSH"
     gene            8373..9098
                     /locus_tag="OPY25_002788"
     CDS             8373..9098
                     /locus_tag="OPY25_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HCS0928366.1"
                     /translation="MLSVIGIGPGSQAMMTMEAIEALQAAEIVVGYKTYTHLVKAFTG
                     DKQVIKTGMCKEIERCQAAIELAQAGHNVALISSGDAGIYGMAGLVLELVSKQKLDVE
                     VRLIPGMTASIAAASLLGAPLMHDFCHISLSDLLTPWPVIEKRIVAAGEADFVICFYN
                     PRSRGREGHLARAFDLLAASKSAQTPVGVVKSAGRKKEEKWLTTLGDMDFEPVDMTSL
                     VIVGNKTTYVQDGLMITPRGYTL"
     gene            9095..9834
                     /locus_tag="OPY25_002789"
                     /pseudo
     CDS             9095..9834
                     /locus_tag="OPY25_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460971.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-6A reductase"
     gene            9953..10681
                     /locus_tag="OPY25_002790"
     CDS             9953..10681
                     /locus_tag="OPY25_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001726449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin cobaltochelatase"
                     /protein_id="HCS0928367.1"
                     /translation="MACERDLAESCPDRDLFRAFTSGMIIRKLRQRDGIDIDTPLQAL
                     QKLAAQGYQDVAIQSLHIINGDEYEKIVREVQILRPLFTRLTLGVPLLSSHNDYVQLM
                     QALRQQMPSLRQTEKVVFMGHGASHHAFAAYACLDHMMTAQRFPARVGAVESYPEVDI
                     LIDSLRDEGVTGIHLMPLMLVAGDHAINDMASDDGDSWKMRFNAAGIPATPWLSGLGE
                     NPAIRAMFVAHLHQALNMAVEEAA"
     gene            10678..11391
                     /locus_tag="OPY25_002791"
     CDS             10678..11391
                     /locus_tag="OPY25_002791"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HCS0928368.1"
                     /translation="MNGKLYALSTGPGAPDLITVRAARILGSLDILYAPAGRKGGDSL
                     ALSIVRDYLGEQTEVRCCHFPMSADGAEKEAVWNEVAAALTAEVEAGKQVGFITLGDA
                     MLFSTWIFLLQRIGCPEWLEIVPGVTSFAAIAARAKMPLAIERQSLAVISCTAPEAEI
                     AQALQQHDSLVLMKVYGRFARIKALLAQAGLLECALMMSEATLPGEQCWRHLHEVNDD
                     RALPYFSTILVNKQWEYAE"
     gene            11388..12124
                     /gene="cbiM"
                     /locus_tag="OPY25_002792"
                     /pseudo
     CDS             11388..12124
                     /gene="cbiM"
                     /locus_tag="OPY25_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460968.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter S component CbiM"
     gene            12126..12407
                     /locus_tag="OPY25_002793"
     CDS             12126..12407
                     /locus_tag="OPY25_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HCS0928369.1"
                     /translation="MKKTLMLLAMVVALVILPFFINHGGEYGGSDGEAESQIQALAPQ
                     YKPWFQPLYEPASGEIESLLFTLQGSLGAAVIFYILGYCKGKQRRDDRA"
     gene            12394..13071
                     /locus_tag="OPY25_002794"
     CDS             12394..13071
                     /locus_tag="OPY25_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     transmembrane protein"
                     /protein_id="HCS0928370.1"
                     /translation="MTGLDRLSYQSRWAHVAPQRKFLLWLAMMILAFVLPPVGQGIEL
                     LIIAGLSCWLLRISLWRWCRWMAIPFGFLLVGVITIIFSISREPQMLLAGISVGPYWI
                     GITRAGVVTANETFWRSLTALSATLWLVMNLPFPQLISLLKRAHIPRLLTEQILLTWR
                     FLFILLDEAVAIRRAQTLRFGYCSLPNGYRSLAMLTGLLFTRVLMRYQQMTTTLDIKL
                     YQGDFHL"
     gene            13080..13895
                     /locus_tag="OPY25_002795"
     CDS             13080..13895
                     /locus_tag="OPY25_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCS0928371.1"
                     /translation="MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLF
                     MNLSGLLRPQKGAVLWQGKPLDYSKRGLLALRQQVATVFQDPEQQIFYTDIDSDIAFS
                     LRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLL
                     DEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILMHG
                     APGEVFACTEAMEHAGLTQPWLVKLHTQLGLPLCKTETEFFHRMQKCAFREAS"
     gene            13892..15412
                     /locus_tag="OPY25_002796"
     CDS             13892..15412
                     /locus_tag="OPY25_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HCS0928372.1"
                     /translation="MTQAVMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMAL
                     NSGITPDGKEMGRAQIFQAEAAGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAV
                     SYHDYKPRLREQILAVYNSLAQEYDVIVLEGAGSPAEINLRDRDIVNMGMAEMAQCPV
                     ILVADIDRGGVFAAIYGTLALLHKQERDRVKGVIINKFRGDVALLYSGIEQIESLTGV
                     PVLGVMPWLDVDLEDEDGVALQNDKYRGNAPRDITIAIVQLPHISNFTDFNALAAQPD
                     VRIRYIRRPEALTDADLVILPGSKNTLSDLAWLRESGMADAVLQTHRQGVPVMGICGG
                     YQMLGDTIVDEVESGLGTQPGLGLLNTITRFAQDKTTTQVNATMSGELPGWLAAAAGL
                     PVRGYEIHMGETVLQEGCCTAMTLQKNGCSVADGAVTADGLAFGTYLHGLFDSDAFTR
                     AVVNGLRARKGLAPWETTFCYAEHKARQFDLLAEAMRQHIDIDKIYTIMQQHQEPV"
     gene            15409..15954
                     /gene="cobU"
                     /locus_tag="OPY25_002797"
     CDS             15409..15954
                     /gene="cobU"
                     /locus_tag="OPY25_002797"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HCS0928373.1"
                     /translation="MMILVTGGARSGKSRHAEALISDAPQVLYIATSQILDDEMAARI
                     QHHKDGRPAHWRTAECWRHLDTLITADLAPDDAILLECITTMVTNLLFALGGENDPEQ
                     WDYAAMERAIDDEIQILIAACQRCPAKVVLVTNEVGMGIVPENRLARHFRDIAGRVNQ
                     RLAAAADEVWLVVSGIGVKIK"
     gene            15951..16694
                     /gene="cobS"
                     /locus_tag="OPY25_002798"
     CDS             15951..16694
                     /gene="cobS"
                     /locus_tag="OPY25_002798"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HCS0928374.1"
                     /translation="MSKLFWAMLAFISRLPVPSRWSQGLDFEQYSRGIVMFPFIGLIL
                     GGISGLIFILLQPWCGIPLAALFCILALALLTGGFHLDGLADTCDGIFSARRRERMLE
                     IMRDSRLGTHGGLALIFVLLAKILVVSELALRGTPMLAALAAACAAGRGSAVLLMYRH
                     RYAREEGLGNVFIGKVSGRQTCITLGLAVIVATVLLLGMQGLATMVVTLAAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELIFLLALL"
     gene            16721..17791
                     /gene="cobT"
                     /locus_tag="OPY25_002799"
     CDS             16721..17791
                     /gene="cobT"
                     /locus_tag="OPY25_002799"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HCS0928375.1"
                     /translation="MQTLHALFRDIPAPDAEAMARAQQHIDGLLKPPGSLGRLETLAV
                     QLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVSPKIVTAIQAANMTQGTTGVCVL
                     AAQAGAKVHVIDVGIDAEPIPGVVDMRVARGCGNIAVGPAMSRSQAEALLLEVSRYTC
                     DLAKRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVR
                     RAIAINQPNPRDGIDVLSKVGGFDLVGMTGVMLGAARCGLPVLLDGFLSYSAALAACQ
                     IAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSGAALAMPIVEAACAM
                     FHNMGELAASNIVLPEGNANAT"
     gene            17869..18798
                     /gene="ldtA"
                     /locus_tag="OPY25_002800"
     CDS             17869..18798
                     /gene="ldtA"
                     /locus_tag="OPY25_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HCS0928376.1"
                     /translation="MRRITPFFPFFVLLVSHFSLAISYPLPPEGSRLVGQPVTIAVPQ
                     NNTQPLESFAARYGQGLSNMLEANPGVDVFLPQSGSTLVVPQQLILPDTVREGIVVNV
                     AEMRLYYYPAGTNTVEVLPIGIGQAGRETPRNWVTAVERKQDGPVWVPTANTRREYAK
                     EGKTLPAMVPAGPDNPMGLYAIYIGRLYATHGTNANFGIGLRVSQGCIRLRNDDIKYL
                     FDHVPVGTRVQIIDRPVKFSVEPDGSRWLEVHEPLSRNRAEFESDKKVPLPVTPVLRT
                     FIKGDDVDTSRVNEVLERRSGMPVNISAGRSGL"
     gene            complement(19024..19099)
                     /locus_tag="OPY25_002801"
     tRNA            complement(19024..19099)
                     /locus_tag="OPY25_002801"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19064..19066),aa:Asn,seq:gtt)
     gene            19259..20716
                     /locus_tag="OPY25_002802"
     CDS             19259..20716
                     /locus_tag="OPY25_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EmmdR/YeeO family multidrug/toxin efflux MATE
                     transporter"
                     /protein_id="HCS0928377.1"
                     /translation="MWFQLSSLRSILNVSTALRQVVVRTPWYAKRKSYKVLFWREITP
                     LAIPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVV
                     VAFSLGKRDRRRARAAARQSLVIMTLFAVVLAVVIHYFGSEIINIVAGEATPEVKGLA
                     LTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLMINGGMNILNIVISSILIYGAFSW
                     QGLGFAGAGLGLTISRYIGAVAIIWVLMIGFNPALRIPLKSYLKPLNFGIIWEVMGIG
                     IPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVAALINLPGNALGSASTIITG
                     KRLGTGQIGQAERQLRHVFWMSTIVLTAIAWGTAPFAGLFASFYTQEQDVKEVVKVLL
                     WLNAAFMPIWAAAWVLPSGFKGARDVRFAMWVSMLGMWGCRVVAGYTLGIVLGMGVVG
                     VWLGMFLDWAVRGALFYWRLISGRWLWRYPRVKRE"
     gene            20857..20932
                     /locus_tag="OPY25_002803"
     tRNA            20857..20932
                     /locus_tag="OPY25_002803"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20890..20892,aa:Asn,seq:gtt)
BASE COUNT         4468 a         5255 c         6395 g         5198 t
ORIGIN      
        1 gccaccaccg gtctggcggt tgtggttgtc aatattcatg gtgatgaaat atctgagcta
       61 ttcaatttca cgccgttttg tcagttgatg cggcagcatc cccagcatag tacacgttgt
      121 cgtatgagcg atcgctgcgg gggactggag gcatcgaagt ccgatcaacc ctgtatttat
      181 cgttgtcatg ccggtctaac ggatttttct attccgctgg taatcgcagg gcatttagtt
      241 ggctttgttt tatgcgggca ggttcgttta agtaatgacg tggagctggt aaacattctt
      301 aatgtcgacg atcgctggca ggctgaccct gagctcttga atgaatttcg gaatgtgcca
      361 gagatggact attcacgcgt tatcgcttcc gccgatcttc ttaaactgat agttgagaat
      421 tgcctgaaaa aacagctcaa tttcgtggtt atcaaagaca atccgcagca atcggaggca
      481 aataaaacca ctcgtggccc cactccgcat gacagtaaaa tgaaaaaagc gcttcgctat
      541 attgatgcgc atttgtccga cgatcttcgt cttgaggatg tcgcctcaca tgtctatctc
      601 agcccctatt acttcagtaa gctattcaag aaatatcagg gaatcggatt taatgcgtgg
      661 gtgaaccgcc agagaatggt tagcgccaga gaattgcttt gccatagtga ctggagtatt
      721 gccagtattg cgcgtaattt aggcttttcg caaaccagtt atttttgcaa agtcttccgc
      781 cagacctatc aggttacgcc gcaggcttat cgtcagcaga taaatgagaa ttctcatcct
      841 ccatcgatat aaatagcaat attttgctat tgccgatttt tgatagtgtt ttgtatctta
      901 atcatttcag aaagaaaatt tatctggtgt aacaataaat tgtcatagcg caacaaaata
      961 ataaaattta gggcataaac tgcaccagtt tttatttttg tgatgaagta cagtgtcagg
     1021 aaagataagt tttattacgc tttgtcgata cgttttatcg tcaatatacc ggtaaggatg
     1081 agtagattaa cgtcagatga gcaaccgctc aggctattgc tcacagaaat gtaaaacgta
     1141 gcacattatt aattgccgtt atgggtgtgc cgtacagcca taacgtaaac caacaggttt
     1201 gccacatttg tggtagggaa gggggtgaaa atcccccgca gcccccgctg ctgtgatgct
     1261 gacgaccccg taaagaccac tgatcgcaag attgggaagg acgggcgagg aggacgctaa
     1321 gccagaagac ctgcctgtcg gtgataacca acaacttcgg tgggaagtgg gttgcgaaga
     1381 cgcgtacagt cgaaagactg aacatgcgcg tacctgtata cccctaccac cctgaacagg
     1441 atcagggtaa tggcggcaag gcatcacgct ttattcttgc aggcacagga agcggttgcg
     1501 gcaaaaccac ggtgacgctt ggtttgttga ggctgctgca aaaacgcgcg ctgcgcgtac
     1561 agccgtttaa agttgggcca gattaccttg ataccggctg gcataccgct atctgtggcg
     1621 tggcgtcccg taatcttgac agtttcatgc ttcctcctcc tgttctcaac gccttatttt
     1681 gcgaacaaat gcggcaggcg gatatcgctg tcattgaagg cgtcatgggg ctgtatgacg
     1741 gctatggcgt cgaccccaat tactgcagca cagccgcgat ggccaaacag cttggttgcc
     1801 cggtcatcct actggtggac ggcaaggctg tttcaacgtc gcttgcggct atcgttatgg
     1861 gatttcagca cttcgacccg accctcaacc tcgcgggcgt gattgtgaat cgcgtcacta
     1921 gcgacgccca ctatcagctc ctcaaaaatg ccattgaaca ttattgctca ctgccggtac
     1981 tggggtatgt ccctccttgc gacggcgtcg cattacctga acgccacctg gggttgatta
     2041 ccgccagaga atccctcgtc aatcagcaat catggcatga ttttgccgcc acgctggaac
     2101 aaacagtgga tgtggatgcg ctactctcgc tgagcctgtt atcagcgctt ccggcgggaa
     2161 tgtggcctga acgccccgat aacacagcgg gggcagggct gacgcttgct ctggcggatg
     2221 atgaggcctt taacttttat taccccgata acatcgattt gctggagcgt gccggcgtta
     2281 acattgtgcg ttttagccca ctgcatgacc gcgcattgcc tgattgtcag atgatctggc
     2341 tgggcggtgg atatcctgaa ttatacgccg cggatctggc ggcaaatacg gcgatgttaa
     2401 aacatttgcg ggcggcgcat cagcgcggcg tggcgattta cgcggagtgt ggcggtctga
     2461 tgtatctggg gagcactctg gaggatagcg gcggggaaat tcatcagatg gcgaatatta
     2521 tccccggtca cagcaaaatg ggtaagcgac ttacccgctt tggttactgt gaggcgcagg
     2581 ctatgcagcc aacgctattg gcggtgcctg gcgagatagt gcgcggccat gaatttcact
     2641 actcagattt tatccccgaa acacccgccg ttatggcctg tcgtaaggtt cgcgatggcc
     2701 gcgtgttaca agaatggact ggcggctggc agacaggcaa cacgtttgcc agctatctgc
     2761 acgtccattt cgcccagcgt ccggaaatgt tgcagcactg gctggcggcg gcgaggcgag
     2821 tattatgacg atccttgcct ggtgtatcgc ctgggtgctg gattttatca tcggcgaccc
     2881 tcaacactgg ccccatccgg tacgctggat aggccgatta attacgtttg tgcagcgtat
     2941 tgtgcgtcgc tattgtcccg gcgataaagc gctgcggatt ggcggcggcg taatgtgggt
     3001 tgtggttgtc ggggtgacct ggggcgtggc atggggcgta ctggcgctgg cgcagcggat
     3061 tcacccctgg tttggctgga gcgtcgaagt ctggatgatc tttaccacgc tggccggacg
     3121 ctctctggcc cgcgccgcgc aggaggttga acgaccgttg cgggagaacg accttgcgga
     3181 aagccgaata aaactctcct ggatcgtcgg gcgcgatacg tcgcaacttc agccagcgca
     3241 gatctatcgc gccgtggtgg aaacggttgc agaaaacacc gttgacggca ttatcgcgcc
     3301 gctctttttc ctctttctcg gcggcgcgcc gctggcgatg gcctacaaag ccgtcaatac
     3361 cctggattca atggtgggct acaaacatga aaaataccgg gcgattggta tggtcagcgc
     3421 ccgtatggac gacgtagcga actatttgcc cgcccgactg agctggctgt tgctgggcat
     3481 tgcggcagga ctgtgtcgcc tgagtggttg gcgggcgctg cgtattggct ggcgtgaccg
     3541 ttataaccac agtagcccaa attgcgcctg gtcggaagcg tgtgtggctg gcgccttagg
     3601 aatccagctc ggtggcccaa ataactactt tggcgagcgt gtggacaagc cctggatcgg
     3661 cgacgcgcag cgcggtattt ccgtggacga tatttcccga acgattcgat tgatgtgggt
     3721 cgcttcaacc ctggcgctgg cgctgtttat tgcggcgcgg tgcgggttat ctggcgtggc
     3781 ctgaggacga cagtatgcat tatatccagc agccccaaac cattgaggcc aacagtttca
     3841 ccattattag cgacattatt cgcgaaacgc gtcctgatta ccgtttcgcc agtccgctcc
     3901 atgaggccat tatcaagcgg gttattcata ccaccgccga tttcgactgg ctggacattt
     3961 tgtggttctc tgccgatgcg ctggagcagc tttgtgatgc gctacgccaa ccgtgcatta
     4021 tttataccga taccacgatg gcgctgtccg gcattaataa aagattactg gcgacgtttg
     4081 gcggcgagtg tcgctgttat atcagcgatc cgcgcgtggt gggcgtaccg gtaggctttg
     4141 tcggcgcggc ggagtccaaa gaggcgctca cccatagcca ttttcccgcg gttgccgcgt
     4201 tagggcgtaa aggcggcagt aacgtggctg ccgctatcgt caatgcgctg ctctatcacc
     4261 tccgggaggc ctgatgagcg agctttcttt tgacgcgccg gtctggcgcc acggtaaagc
     4321 gttacgtaaa ggatatacca ccggttcctg cgcgacggcg gcggcaaaag tcgccgagct
     4381 gatggtatta cgtcaacatc tgattcatca ggtctccatc gtcacgccgt cgggcgtcac
     4441 gctatgcctg aacgtggagt cgccgcacat tgaaggccag caggcgatag ccgcaattcg
     4501 taaagatggc ggcgatgacg tggatgccac gcacgggatg ctgatttttg cccgcgttac
     4561 gctcaacgac agcggtgaga ttacgctcac tggcggcgaa ggtattggta cggtaacgcg
     4621 taaaggggtt ggactgccgc tcgggagcgc tgccatcaat cgtacgccgc gccataccat
     4681 tgaatctgcg gtgcgcgaag cgataggccc ggcgcgtggg gctgatgtgg agatttttgc
     4741 cccggaaggc gaagtgcggg cgcagaaaac ctataactcg cggcttggca ttcttggcgg
     4801 catttccatt attggcacta ccggtattgt gacgccgatg tcggaagaaa gctggaaacg
     4861 ctcgctatcg ctggaactgg agatcaaacg ggcgtcagga ttaacgcggg tgatactcgt
     4921 gccgggcaac cacggcgaac ggtttgttcg cgaacaaatg ggcgtcgaca cacaggcggt
     4981 cgtcaccatg agcaattttg tcggctacat gattgaagag gcggtacggc tgggattttg
     5041 ccagatagtg ctggtgggtc atcctggaaa attgatcaaa atcgccgccg ggatctttca
     5101 tacccatagc catatcgccg atgcgcgcat ggaaacgctg gtcgcgcatt tagctttact
     5161 gggcgcgccg ctggagttac tcaccctggt cggcgattgc gataccactg aagcggcaat
     5221 ggagcacatt gaagcatatg gcttcgggca tatctataac catcttgcca ggcgtatttg
     5281 tttgcgagtc atgcagatgc tgcgttttac caaaacgccg cctgtctgcg acgccatcct
     5341 gttttctttt gataaccata ttctcggcag taatcgtccc gtcgacgaga ttgctaagga
     5401 gctgcaatgc taacggtcgt gggaatgggg cccgctggac ggcatttgat gacgcctgcg
     5461 gcgctggaag cgatagacca cgccgatgcg ctggcaggcg gtaaacggca tttggcgcag
     5521 tttccggcgt ttggcggcga acgatttacg ctgggcgcgg atattggcgc gttgttgtca
     5581 tggattgccg cccgtcggga taaagggatc gtggtgctgg cctccggcga tccgctgttt
     5641 tatggcatcg gtacacgcct ggtggcgcat tttggtatcg aacaggttcg cattatccct
     5701 ggcatcagcg ccgtacagta tctgtgcgca caggctggaa ttgatatgaa tgacatgtgg
     5761 ttgaccagta gccacggtcg ttgcgtcagc ttcgagcagt tggcgaacca tcgcaaagtg
     5821 gcgatggtca cggatgcccg ctgcgggccg cgggaaatcg cgcgggaact ggtcgcgcgt
     5881 ggtaaagggc atcgcttgat ggtgattggt gaaaatctgg cgatggaaaa tgagcggatc
     5941 cactggctac ccgtcagtgc ggtcaacgcc gactatgaaa tgaatgcagt ggtgatcctg
     6001 gatgaaagat gagctttttc tgcgcggcga gaacgtgcca atgaccaaag aggcggtacg
     6061 ggcgctggca ctgtcgaaac ttgagctcca ccgcgccagt cacctgattg acgtcggggc
     6121 gggaacggga agcgtctcaa ttgaagcggc gctgcaattt ccttcgttgc aggtgacggc
     6181 tattaagcgt aatcctgccg cgctacggct gcttgatgag aatcgtcagc gctttgcctg
     6241 cggcaatatc gatattctcc ccggcgaagc gccaatgacc ataaccggga aagccgatgc
     6301 ggtgtttatg ggcggcagcg gcgggcatct gacggcgctg attgactggg cgatgggcca
     6361 tctgcatccc ggtggccgtc tggtgatgac ctttatcttg caggaaaacc tccatagcgc
     6421 gctggcgcat cttgtgcaca tcggcgcatg ccgaatggac tgtgtacagc ttcagctttc
     6481 atcgttaacg ccgctggggg cgggacacta tttcaaaccg aacaaccctg tttttgttat
     6541 agcctgtcag aaggaagaaa accatgtcag agacatttga tccacgctgt gtatggttcg
     6601 tcggcgccgg gccgggcgat cgcgagctga tcacgcttaa aggctaccgc ctgctgcaac
     6661 aggcgcaggt agttatctat gccggttcgc tgatcaatac cgaactgctg gattactgcc
     6721 ccgcgcaggc agaacgctac gacagcgccg aactgcatct tgagcagatt atcgagctga
     6781 tggccgcggg cgtgaaagcg ggaaaaacgg tggtgcggtt gcaaacgggc gatgtctcgc
     6841 tgtacggctc cgtgcgtgag caaggcgaag agttaacccg ccgtggtatc gactggcagg
     6901 tagtgcctgg cgtcagcgcg tttctcggcg ctgcggcgga gctgggtgtg gaatataccg
     6961 taccggaggt atcgcagagt ctcattatta cccgtctgga agggcgtacg ccagtaccgg
     7021 cgcgcgaaca actggaggcg ttcgccagtc accagacgtc gatggcgatt tatctctccg
     7081 ttcagcgtat tcatcgggtg gcggaacgtc tcattgccgg cggttatccg gcaactacgc
     7141 ctgtcgcagt catctataag gctacctggc cggaaagcca gaccgttcgc ggcacgttag
     7201 cggatattag cgacaaagta cgtgatgctg gcatccgtaa gacggcgcta atcctggtcg
     7261 ggaattttct gggtaaggag tatcactact caagacttta tgcagcggac tttagccatg
     7321 aataccgtaa agcctgaatc cattgcgttg ttttgcctga cgcccggcgg cgtggcgctg
     7381 gcaaagagac tcgccgcgat gctgccgtta acctgcttta ccagtgaaaa actgcgggaa
     7441 gagggattta ttcccttcga tggcggattc gctaataccg cccggcaggc ttttaccact
     7501 tataccgcgc ttatttttat cggcgcgacc ggcattgccg ttcgtgtcct ggcgccgtta
     7561 gtgaacgaca agttcagcga tccggcggtg gtcgtcattg atgaacgtgg tcagcatgtc
     7621 attagcctgc tttccggtca tgcgggcggg gccaatgcct tgacgcgcta cctggcagga
     7681 atgttaggcg ccgatccggt gattaccacg gcaacggatg tcaatgagat gtccgcgttg
     7741 gacaccttag ctttccagct taacgcccgc atgtccgatc ttcgaacggc ggtaaaaacc
     7801 gttaaccaga tgttggtcag tcatcaacgt gtggggttat ggtgggatgc cgaactaacg
     7861 gaagagatcg gccagtgtga tattcgcggt tttatccctg ttgatgattt gcagcggttg
     7921 cctgaactgg atgcgcttat ctgcgtctct ttgcgtaatg acctccctga gcttcccgta
     7981 ctgcactgga aactggtgcc ccagcgcgtg gtggcgggaa ttggctgtcg ccgcgatacg
     8041 ccatttcccc tgttagcgac attactggcg cgtcagcttg aagcgcagaa actcgatccg
     8101 ctggcgttaa aagcgattgg cagcgtcacg ctcaaaaaag gggagccggg gcttattcag
     8161 ctcgcctcct gctgccgcgt gccttttaaa acctttaccg ccgaagcgtt gcgcgaattc
     8221 gaacaccatt ttcccggttc tggcttcgtc agaaaaacgg tgggcgttgg cagcgtatcc
     8281 ggcccggctg cgtggttatt aagccagggt caattgttag gcgaaaccct gcgcgaacag
     8341 ggcgtcacta ttactttggg agtttcacac tgatgttaag cgtaatcgga attggccctg
     8401 gctcacaggc aatgatgacg atggaggcga ttgaggcgct tcaggcggcg gaaatcgtcg
     8461 tgggctacaa aacctatacc catctggtta aagcattcac cggcgacaaa caggtgatca
     8521 agaccggcat gtgtaaggaa attgaacgct gccaggcggc tattgaactg gcgcaggccg
     8581 ggcataacgt agcgctgatt agcagcggcg acgccggtat ttacggcatg gcgggactgg
     8641 tgctggagct ggtgagcaag cagaaactgg acgtcgaggt gcggctcatt cctggcatga
     8701 ccgccagcat cgccgccgcc tctttactgg gcgcgccgct aatgcatgac ttctgccata
     8761 tcagcctcag cgacctgctg accccgtggc cggttattga aaaacgcatc gttgccgccg
     8821 gagaggcaga ctttgttatc tgtttttaca acccgcgcag ccgcgggcgc gaagggcatc
     8881 tggcgcgcgc gtttgacctg cttgccgcca gtaaaagcgc gcaaacgccg gttggcgtgg
     8941 tgaaatccgc cggacgtaag aaagaggaaa aatggctgac cacgctcggc gatatggatt
     9001 ttgaaccggt agatatgacc agtctggtca tcgttggtaa taaaacgacc tatgttcagg
     9061 atgggctgat gataacgccg cgaggttaca cgctgtgaat gagggggagg tgctggtggt
     9121 gggcggcacc agcgatgcgc gcgcgttatg ccgacaactg ggtgcggcga acgtcgcgta
     9181 caccttatct gtggcgacgc cagccggaaa agcgctggct ggcgacatta aaggacaggt
     9241 gcgctgtggt cgtctggagt acgggcagat ggtcgcatgg ctaaaagaaa accgtactcg
     9301 ctgggtaata gatgcgtcgc atccttatgc agaaatggtc agccataacc tccttcgcgc
     9361 ctgtgaaacg gcgggcgtgt tgttaagtcg ttatcagcgt ccggagcagc ttagcaatct
     9421 gacgcatccg cttctctata cggcgcgcag tattgccgat gcctgcgaga tagcgaggcg
     9481 ttttggtccg cgcgtgttac tgacgaccgg cagtaaagat ctggccgtct ggcgtgccgg
     9541 gctggcggaa aaaacgttgc tggcgcgcgt actgcccgtg gcggaggtga ttcaacgctg
     9601 cagcgaactg gggttcggcg ttggagaaat tttcgcactg tgtgggccgt tcagcgctga
     9661 ttttaacgcc gcgttttacc gccagtgccg ggctgacgtg gtcattacca aagcgtccgg
     9721 cgcggagggg gatatcagga aaaagttcag ccctgtctgg atgcgggcat tccctgcatc
     9781 gttattgcgc gcccgacgcc gctcgtgacg ggtgatgagt tactggaaag ctaggccgcc
     9841 tttgcgcagc gtttatcgcg ctggctggcc gcagctaagg agtaaaaatg aaaaaagcgc
     9901 ttctggtggt cagttttggc accagctatc acgacacctg tgaaaaaaca ttgtggcgtg
     9961 cgaacgtgat ctggcggagt cctgtcccga tcgcgacctg tttcgcgcct tcacttccgg
    10021 aatgatcatt cgcaagcttc gccagcgtga cggtatcgac atcgatacgc cattacaggc
    10081 tttgcaaaag cttgcagcac agggatatca ggacgtggcg attcagtcgt tgcacattat
    10141 taacggcgac gaatatgaaa aaattgtccg tgaagtacaa atcttgcgtc cgttatttac
    10201 tcgcctgacg ctgggcgtgc cgctgctgag cagccataac gattatgtgc agctaatgca
    10261 ggcgttgcga caacagatgc catcgctcag acaaacggag aaagtcgttt ttatgggcca
    10321 cggcgccagc catcatgcat tcgcagctta tgcctgcctc gatcatatga tgaccgcgca
    10381 gcgcttcccg gcgcgcgtcg gcgctgtaga aagctacccg gaggtcgaca tcctgatcga
    10441 cagcctgcgt gacgaaggcg tcaccggcat acatttgatg ccattaatgc tggtggcggg
    10501 cgatcacgcc ataaatgata tggcttcaga cgacggcgac tcatggaaaa tgcgctttaa
    10561 cgcggcgggc attccggcga cgccgtggct gagcgggctg ggagaaaacc cggctatccg
    10621 ggcgatgttt gtcgcgcatt tgcaccaggc gctgaacatg gcggtagagg aggcggcatg
    10681 aacggtaaat tatacgcatt aagtaccggg ccaggcgcgc ccgacctgat aaccgtccgc
    10741 gcagcgcgga ttcttggctc gctggacatt ctgtatgcgc ccgccggtcg taaggggggc
    10801 gatagtctgg cgttgtcgat tgtgcgcgac tatctcggcg agcagacgga agtacgttgt
    10861 tgccatttcc ctatgagcgc tgacggcgcc gagaaagaag cggtctggaa cgaggttgcc
    10921 gccgcgctta ccgcagaggt ggaagcgggt aaacaggtcg gttttattac cctgggcgat
    10981 gcgatgctat tcagtacctg gattttttta ctccagagaa tcggctgccc ggagtggctg
    11041 gagattgtcc ccggcgtcac gtccttcgcc gcgatagccg cccgcgcgaa aatgccgctc
    11101 gccatagaac ggcaatcgct ggcggttatt tcttgtaccg cgccggaagc ggaaatagcc
    11161 caggcgctac aacagcatga tagcctggtg ttgatgaaag tgtatggccg attcgcccgt
    11221 attaaagcgt tgctggcgca ggctggcctg ctggaatgcg ccttaatgat gtccgaggcc
    11281 acgctgcccg gcgagcagtg ctggcgccac ctccacgagg tcaacgatga tcgagcgttg
    11341 ccctattttt cgaccattct ggtcaataaa cagtgggagt atgcagaatg aaacttgaac
    11401 agcagcttag acagttgtct ttcagtggac tggctgcagc gctattgctg atggttgtcc
    11461 cgcaacaggc gtttgcgatg catatcatgg agggcttttt accgccagtg tgggcgctgg
    11521 cctggtggtt actgttttta ccctgcttgt ggtatgggct ggtacgctta cggcgtattg
    11581 tgcaggagga taatcatcag aaggtactgc tggcgctgtg cggcgcgttt atttttgtcc
    11641 tgtcccgctc aaaattccgt cggtaacggg gagttgttca catccgaccg gcgttggtct
    11701 ggcggttatc ttgttcgggc ctggggtggt ggcgattctc ggcgcggttg tgctgttgtt
    11761 tcaggcgcta ttgctggcgc acggcggcct gacgacgctt ggcgcaaacg gaatgtcgat
    11821 ggcggtgatt ggcccggttg tcggttatct ggtgtggaaa atggcctgcc gtgccggact
    11881 gcgccgcgat gtcgccgttt ttctgtgcgc gatgctggcg gatttggcaa cctattttgt
    11941 gacttcagtc cagcttggcg ttgcgtttcc cgatccccat gccggagcga cagggtctgt
    12001 tgtgaagttt atggggattt tctgcctcac acagattcct gtcgctattg ctgaaggttt
    12061 attaaccgtc atgatttatg accagttaac caaacggcaa gtgattaccg tacaaggaca
    12121 ttaaaatgaa aaaaacgttg atgttgttag cgatggtggt ggcgctggtg attctgccgt
    12181 tttttattaa ccatggcggt gaatatggcg gttcagacgg cgaagcggaa agccagattc
    12241 aggctcttgc gccgcagtat aaaccttggt ttcagccgtt atatgaaccc gccagcggtg
    12301 aaattgaaag cctgctgttt acccttcagg gctctcttgg cgcggcggtg attttttata
    12361 tcctggggta ttgcaaaggt aaacaacgcc gtgatgaccg ggcttgatcg actcagctat
    12421 caaagccgct gggcacacgt tgcgccgcag cgcaagtttt tgctgtggct ggcgatgatg
    12481 atactggcgt ttgttctgcc gcctgtaggg cagggcattg agctgctgat cattgccgga
    12541 ttgagctgtt ggctattgcg catatccctc tggcgttggt gtcgatggat ggcgatacct
    12601 tttggatttt tgttggtcgg cgtgataacg attatcttca gcatcagccg cgagccgcaa
    12661 atgctgctgg ctggcatatc tgttgggccg tactggatcg ggattacccg tgcgggcgtg
    12721 gttacggcga atgaaacgtt ctggcgtagc ctgacggcgc tgtccgcgac gttgtggctg
    12781 gtgatgaacc taccgtttcc gcagttaatt agcttgctta agcgcgcgca tattccacgc
    12841 ctgcttaccg agcaaatcct gttaacgtgg cgctttctct ttattcttct ggatgaggcg
    12901 gtggcaatcc gtcgtgcgca aacgctgcgt tttggttatt gcagcctgcc gaacggctat
    12961 cgatctctgg caatgctgac tggactcctg tttacgcggg tgttaatgcg ttatcagcaa
    13021 atgaccacca cgctggatat caaactgtat cagggtgatt ttcacctgta aggactatta
    13081 tgcttgccac ttcagacctg tggtttcgtt atcaggatga gccggtactt aaagggttaa
    13141 atctggattt ttcgctctcg cctgttaccg gtttggtggg cgcgaacggt tgtgggaagt
    13201 ctacgctttt tatgaacctg agcggcctgt tgcgtccgca aaaaggggcc gtattgtggc
    13261 agggaaaacc gttggattac agcaagcgcg gactactggc gctgcgccag caagttgcga
    13321 cggtttttca ggaccctgaa cagcagattt tttatactga tatcgatagc gacattgcgt
    13381 ttagtttacg taatttgggt gtgccggagg cggaaatcac gcgccgcgtc gacgaggcgc
    13441 taacgctggt tgacgcccaa cattttcgcc atcagcccat tcagtgtttg agtcatggac
    13501 aaaaaaaacg tgtggctatc gccggagcgc tggtgctaca ggcgcgctat ctattgctgg
    13561 atgaacccac tgctggtctt gatcccgcag ggcgcactca gatgattgct atcatcaggc
    13621 ggattgtggc gcagggaaat catgtcatta tctccagcca tgatatcgat cttatttatg
    13681 aaattagcga tgccgtatac gtgttacgcc agggccagat cctgatgcat ggcgcgcctg
    13741 gcgaggtttt cgcgtgtacg gaagcgatgg aacacgcggg gctaacccag ccctggctgg
    13801 tcaaacttca tactcaactg ggactgccgc tgtgtaaaac agaaacggag ttttttcatc
    13861 gaatgcaaaa gtgcgcattc agggaggcgt catgacgcag gcagttatgt tgcaggggac
    13921 ggcatccgac gtcggcaaaa gtgtgctggt ggccggttta tgccgcattt tttatcagga
    13981 tggtctgcgt accgcgccgt ttaaatcgca aaatatggcg cttaattctg gtattacgcc
    14041 ggatggtaaa gagatggggc gggcgcagat ttttcaggcg gaagccgcgg ggatcacgcc
    14101 agatgtgcgt atgaatccgg tgctgctcaa accgaccagc gatcgccagg cgcaggtcgt
    14161 gctgatgggg aaagtggcga ccaatatgga tgcggtgagt taccatgact ataaaccgcg
    14221 tttgcgtgag caaatccttg cggtctataa cagcctggcg caggaatatg acgttattgt
    14281 gctggaaggc gccggaagcc cggcggaaat caatctgcgc gatcgcgata tcgtcaatat
    14341 gggaatggcg gaaatggccc agtgtccggt tattctggtg gcggatatcg accggggcgg
    14401 cgtattcgcc gctatttatg gcacgctggc gctactgcac aaacaggagc gtgacagagt
    14461 aaagggcgtc attatcaaca aattccgcgg cgacgtggcg ctactctatt ccggtatcga
    14521 acaaatcgaa tcgcttaccg gcgtcccggt tctgggagtg atgccatggc tggatgtgga
    14581 tctggaagat gaagatggcg tcgcgctgca aaacgataaa tatcgcggta acgccccccg
    14641 tgatatcact attgccattg tgcaactgcc acatatttct aactttacgg attttaacgc
    14701 tctggcggcg cagccggatg tgcgcatacg ctatattcgc cgcccggaag cgttgactga
    14761 cgctgatctg gtgatcctgc cgggcagtaa gaatacgctg agcgacctcg cctggctgcg
    14821 cgaaagcggg atggcggatg cggtattgca gacacatcgg cagggcgtgc cggtgatggg
    14881 aatttgcggt ggctaccaga tgctgggcga cactattgtg gatgaggtgg agtcggggct
    14941 gggtacgcag ccgggcctgg gactgcttaa tacgatcact cgctttgcac aggataaaac
    15001 cacgacgcag gttaacgcga caatgtcagg cgagctgccc ggctggctgg ctgccgcggc
    15061 ggggctaccg gtacgcggtt atgaaatcca catgggggaa acggtgctgc aggaaggatg
    15121 ctgtacggcc atgacgttac agaaaaatgg atgctctgtg gcggatggcg cggtcaccgc
    15181 cgacggactg gcgtttggca cttaccttca cggtctgttt gacagcgatg cctttacccg
    15241 tgcggtggtc aatgggttac gggcgcgaaa agggcttgcg ccgtgggaaa cgactttttg
    15301 ttatgcggag cataaagcgc ggcaatttga tctgctggcg gaagcgatgc ggcaacatat
    15361 tgatattgat aaaatttaca ccatcatgca acagcatcag gagccggtat gatgattctg
    15421 gtgacgggcg gggcgcgtag tggtaaaagc cgtcatgctg aagccttaat tagcgatgcg
    15481 ccgcaggtac tgtatatcgc cacctcgcag attcttgatg acgagatggc ggcgagaatt
    15541 cagcatcata aagatggcag gccggcacac tggcggaccg cagaatgctg gcggcatctt
    15601 gatacgttga ttaccgcgga tcttgcccct gacgacgcga ttttgctgga atgtattacc
    15661 accatggtga cgaatctgct gtttgcgctg ggaggcgaaa acgatcccga acagtgggat
    15721 tacgcggcga tggagcgcgc cattgacgat gaaattcaga ttttaattgc agcctgccag
    15781 cgctgcccgg cgaaagtggt actggtgaca aatgaagtgg gaatggggat cgtcccggaa
    15841 aaccgcctgg cgcgccattt tcgtgatatt gccggtcggg tcaaccaacg actggcggca
    15901 gcggcggatg aggtctggct ggtggtctca ggtattggag tcaaaattaa atgagtaagc
    15961 tgttttgggc catgctcgct tttattagcc gcttgcccgt gccgtcacgc tggtcgcagg
    16021 gactggattt cgagcagtat tcgcgtggga tcgtgatgtt tccctttatc gggttgattc
    16081 tgggggggat tagcggcctg attttcatcc tcctgcaacc ctggtgcggt attccgctcg
    16141 cggcgttgtt ctgtattttg gcgctggcgc tgctgaccgg tggttttcac ctggatgggc
    16201 tggccgatac ctgcgatggc attttttccg cgcgccgccg cgagcgaatg ctggagatta
    16261 tgcgcgatag tcgtctggga acccatggcg ggctggcgct tatttttgtg ctactggcaa
    16321 aaattctggt ggtcagcgaa ctggcgttac gtggaacgcc aatgttggcg gcgctggcgg
    16381 cggcctgtgc ggccggacgc ggcagcgctg ttttattgat gtaccgtcat cgctacgccc
    16441 gtgaagaggg gcttggcaat gtatttatcg gtaaagtcag cggacggcaa acctgcatta
    16501 ctctgggatt ggcggtaatc gtcgccacgg tattactgct tggtatgcaa ggcctggcca
    16561 caatggtggt cacactcgcg gcgattttca tccttggcca gttgcttaaa cgtacgcttg
    16621 gcggtcaaac cggcgatacg ctgggcgcgg cgatcgaact tggcgaactg atctttctgc
    16681 tggctctgtt atgagccgat tattacggac gagacatctt atgcagacac tacacgcttt
    16741 attccgtgac attcctgcgc cggacgccga ggcgatggcg cgtgcgcagc aacatattga
    16801 cggcctgctc aaaccgccgg gtagcttggg cagactggaa accttagccg ttcagctcgc
    16861 gggaatgccg ggtcttaacg gtacgccgca ggtaggtgaa aaggcggtgc tggtgatgtg
    16921 cgccgaccat ggcgtctggg atgaaggcgt agcggtttcg cccaaaatcg tgacggcgat
    16981 tcaggcggcg aatatgacgc agggaacaac cggcgtatgt gtgcttgccg ctcaggctgg
    17041 tgcaaaggtg catgtcattg atgtcggtat tgatgccgaa cctattccgg gcgtagttga
    17101 tatgcgcgtc gcgcgcggct gcggaaatat tgccgttggc ccggcgatga gtcgctctca
    17161 ggctgaggcg cttttgctgg aggtttcccg ctatacctgc gacctggcga aacgcggcgt
    17221 gaccttattt ggcgttgggg agctgggaat ggcgaacact acgccagccg ccgcgatggt
    17281 cagcgttttt acaggaagtg atgcaaaaga ggtggtgggg attggcgcga atcttccgcc
    17341 ttcccgcatc gataataaag tagacgtcgt gcggcgggcg attgcgatta atcagcccaa
    17401 tccgcgcgac ggcattgatg tgttgtcgaa ggtggggggg tttgatctgg tcgggatgac
    17461 cggcgtgatg cttggcgcgg caaggtgtgg cttacccgta ttgctggatg gctttctttc
    17521 ctactcggca gcgctggcgg cctgtcagat tgcgcctgcg gtgagacctt atctgatccc
    17581 gtcgcacttt tcggcggaaa agggcgcccg catcgcgctc gcgcatttgt ctatggaacc
    17641 ctatttgcat atggcgatgc ggttaggtga aggaagcggc gcggcgctgg cgatgccgat
    17701 cgtggaagcc gcgtgcgcca tgttccacaa tatgggggaa ttggcggcca gtaatattgt
    17761 cctgccggag gggaacgcaa acgcaacata acccgggcgc acaacaccag ccatgtgaga
    17821 aaaaagctat acttaacgca cacctgccgc gacaaaggaa gggatataat gcgtcgtatc
    17881 acaccttttt ttccgttttt cgtcttgttg gtaagccatt tctcgctggc tataagctat
    17941 ccgttgccgc ccgaaggcag tcgtctggta ggacagcctg tcacaatcgc cgtacctcag
    18001 aacaatactc agcccttaga gtcatttgcc gcccgctatg gtcaggggtt gagtaatatg
    18061 cttgaagcga atcccggcgt ggatgtgttt ttacctcagt ctggttccac actggtagtg
    18121 ccgcagcagt tgattctgcc tgacaccgtt cgtgaaggta ttgtggtaaa cgtcgccgag
    18181 atgcgccttt attattatcc cgcaggcacg aatacggttg aggtactacc cattggtatt
    18241 ggtcaggctg gccgtgaaac gccgcgcaac tgggtaactg cggttgaacg caaacaagat
    18301 ggcccggttt gggtgccaac ggctaatacg cgtcgggaat atgctaaaga gggaaaaacg
    18361 ctgcccgcga tggtgcctgc ggggccggat aaccctatgg ggctatacgc aatatatatc
    18421 ggcaggttat atgccaccca tggcactaac gctaactttg gcattggcct tcgcgtcagt
    18481 cagggctgta tccgtttacg caatgacgat attaaatatt tattcgacca tgttcctgta
    18541 ggaacccgcg ttcagattat cgacaggccc gttaaatttt cggtagagcc ggatggcagt
    18601 cgttggctgg aggtacacga accgctttct cgcaaccgtg ctgaatttga gtcagacaaa
    18661 aaagttccat tgcccgttac gccagtgctg cgcacgttta tcaaagggga tgacgttgat
    18721 acttcgcggg ttaatgaggt gctggagcgc cgttccggaa tgccggtcaa cattagcgca
    18781 ggcaggtctg gcctttaaat atcctgccac attgctggtt ttcatgggct ggaacatctg
    18841 tattagtagt gagtgtcatg gcaggggctt cattttctca acgaaccgcg aggccgccga
    18901 ttaagccccc aaaaactatg gatgccaaaa agcccggaaa accttatcag gtcaaccggg
    18961 taaagataag ttcttatttt ttaaacgtct ccggactcgc agggatatcc cgaaactaaa
    19021 atctggctcc tctgactgga ctcgaaccag tgacatacgg attaacagtc cgccgttcta
    19081 ccgactgaac tacagaggaa tcgtgtgggg tcgtatatta gcggcggaaa aatttttgtc
    19141 aaaccccatt taacccctta cagattcgat tgcgggttat ctcatcactt tgttgcattt
    19201 gcagacattt tttctgcaaa aagctttgca gccttacgat ttctcgctca ttattgaaat
    19261 gtggtttcaa ctctcttctt taaggtccat tttgaacgtc tccactgcct tacgccaggt
    19321 tgtcgtccgt acgccctggt atgccaaacg caagagctac aaagtgttgt tctggcgtga
    19381 aatcacccca cttgctatcc ccatttttct ggaaaatacc tgtgttttgc taatgggcgt
    19441 gctcagtact tttctcgtca gttggttggg caaggaagca atggcgggcg tggggcttgc
    19501 cgacagtttt aatatggtaa ttatggcttt ttttgcggct atcgatcttg gtactacggt
    19561 ggtggtcgcc tttagcctcg gcaagcgcga taggcgacgg gcaagggcgg cggcgcgcca
    19621 gtcgctggtg attatgacgc tatttgccgt tgtgctggca gtggtcattc attatttcgg
    19681 cagtgaaatt attaatattg tcgcaggcga ggcgacgcca gaagtaaagg ggctggcgtt
    19741 aacgtacctt gaactgacgg tactgagtta tccggctgcg gcaattgcgc taatcggtag
    19801 cggcgcgctg cgtggggcag ggaatacgaa aatcccgttg atgattaacg gcgggatgaa
    19861 cattctcaat attgtcatca gcagcatcct gatttacggg gctttctcct ggcaagggct
    19921 gggttttgcc ggtgcggggc tgggattaac catttcgcgc tacatcggcg cggtagcgat
    19981 tatttgggtg ctgatgattg gttttaatcc ggcgctgcgc attccgctga aaagctatct
    20041 gaagccgttg aatttcggca ttatctggga agtgatgggt atcggtattc cggcgagcat
    20101 tgaatcagtg ctgttcaacg gtggcaagct actgacgcaa atgtttgtcg ccggaatggg
    20161 cactaacgtt attgcgggta actttattgc cttttccgtg gcggcgctta tcaatctgcc
    20221 gggtaacgcc cttggttcgg cgtcgactat tatcaccggt aagcgtcttg gtaccgggca
    20281 aattggtcag gcagagcgtc aattgcgcca tgtattctgg atgtcgacta tcgtacttac
    20341 ggcaatcgcc tggggaacag cgccgttcgc gggtctgttt gcctcatttt atacccagga
    20401 gcaggacgta aaagaggtag tgaaagttct gctctggctt aatgctgcct ttatgccaat
    20461 ttgggctgcc gcgtgggtgc tgccgtcggg ttttaaaggc gcgcgcgatg tgcgatttgc
    20521 gatgtgggta tcgatgctgg ggatgtgggg ctgtcgcgtt gtggcagggt atacgcttgg
    20581 tattgtgctg ggtatggggg ttgtaggggt ttggctgggg atgtttcttg actgggccgt
    20641 gcgtggcgca ctgttttact ggcgtctgat aagcgggcgc tggctgtgga gatacccgcg
    20701 cgtaaagagg gagtaagagc tttttgctgt gaaaatcatc aggaaacggt gaattttaac
    20761 cgaagtgtgg aataaagcag caaacgaact ttttttgtga aaacaggctt tgacaagcca
    20821 ggggcacctc gttaatattc gccccgttca cacgattcct ctgtagttca gtcggtagaa
    20881 cggcggactg ttaatccgta tgtcactggt tcgagtccag tcagaggagc cagattttag
    20941 tttcgggaca tcctggcgag tccggagacg tttaaaaaat aagaacttat ctttacccgg
    21001 ttggcctgag aaggtctgcc gggttttttg acatccatag tttttggggg cttaatcggg
    21061 ggcctcgcgg ttcgctgaga aaatggagcc cccacctatg gcattaaccg ataccgctat
    21121 ccgcaagatt aaacccgtat cagtatgctg acatatagag gtgttcgatt caaacggagc
    21181 gatcacacaa gcttgccagg tgatgcccct ggtgggaatc gcgactgtct ctttcatctg
    21241 atttcagata tttcccgtga tcttgatccg ttctttccca aaagattgat ttctttcatt
    21301 cgaaacaagg atgtac
//
LOCUS       DAJVKX010000074        20412 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000074 DAJVKX010000000
VERSION     DAJVKX010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20412
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.074"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            9..821
                     /locus_tag="OPY25_002804"
     CDS             9..821
                     /locus_tag="OPY25_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0928378.1"
                     /translation="MLELSITLPIKVQNGGLFISRGIGRHPARRLQSWEIIFVEKGCL
                     KIQEECVFCVEAGESLLLWPHRRHIGVEEFPADLKFYWLHFEVKAPDSDPRWLTHLSV
                     PQHTQVADPQALIALFRQFMNEQEKHQRSPALEFIVLLILQQLTVDARQNENAEAAGV
                     SLAWKAQQLIRTHYHLPLSSAVLAKELHCNVDYLGRVYRRVFHLTLTEAIHRQRVREA
                     EKLLISDARSLKEVAERCGFNDVGYFRQIFRKHTGLTPTAWKRRYSKEHVNS"
     gene            complement(982..1677)
                     /gene="araD"
                     /locus_tag="OPY25_002805"
     CDS             complement(982..1677)
                     /gene="araD"
                     /locus_tag="OPY25_002805"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCS0928379.1"
                     /translation="MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPS
                     GVEYEVMTADDMVVVEIASGKVVEGNKKPSSDTATHLALYRRYPQIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQPELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(1671..2531)
                     /locus_tag="OPY25_002806"
     CDS             complement(1671..2531)
                     /locus_tag="OPY25_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCS0928380.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLEWTSAQRASLVNAMLESGVAIPSMCLSAHRRFPFGSRDEAVRQRAREIMTKAIR
                     LARDLGIRTIQLAGYDVYYEEHDEGTQQRFAEGLAWAVEQAAAAQVMLAVEIMDTAFM
                     NSISKWKKWDEMLSSPWFTVYPDVGNLSAWGNDVTAELKLGIDRIAAIHLKDTLPVTG
                     DNPGQFRDVPFGEGCVDFVSIFKTLHELNYRGSFLIEMWTEKASEPVLEIIQARRWIE
                     SRMQEGGFTC"
     gene            complement(2524..3186)
                     /gene="ulaD"
                     /locus_tag="OPY25_002807"
     CDS             complement(2524..3186)
                     /gene="ulaD"
                     /locus_tag="OPY25_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCS0928381.1"
                     /translation="MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGL
                     SAVKALRAQCPEKIIVADWKVADAGETLAQQAFSAGANWMTIICAAPLATVEKGHAVA
                     QSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGHDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWGEK
                     HA"
     gene            complement(3183..4538)
                     /locus_tag="OPY25_002808"
     CDS             complement(3183..4538)
                     /locus_tag="OPY25_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001575123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HCS0928382.1"
                     /translation="MTELWQQCASVISKLLTHTGVSGSQIRGLGISAQGKGLFLLDKS
                     DRPLGKAILSSDRRAMEIVQRWQKEAVPQKLYPLTRQTLWTGHPVSLLRWVKENEPQR
                     YAQIGSVMMTHDYLRWCLTGVKGCEESNISESNLYNMATGQYDPRLTEWLGISEIDSA
                     LPPVVGSAEICGEITAQAAAITGLAAGTPVVGGLFDVVSTALCAGIEDESTLNAVMGT
                     WAVTSGIAHGLRDHEAHPYVYGRYVNDGQYIVHEASPTSSGNLEWFTAQWGYLSFDEI
                     NQAVASLPKAGSDLFFLPFLYGSNAGLEMTCGFYGMQALHNRAHLLQALYEGVVFSHM
                     THLNRMRERFTEVCALRVTGGPAHSDVWMQMLSDVSGLRIELPQVEETGCFGAALAAR
                     VGTGVYRDFHEAQRDLQHPVRTLLPDMTAHALYQRKYRQYQDLIEALQGYHARIKEHA
                     L"
     gene            complement(4560..5312)
                     /locus_tag="OPY25_002809"
                     /pseudo
     CDS             complement(4560..5312)
                     /locus_tag="OPY25_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462573.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DctP family TRAP transporter solute-binding
                     subunit"
     gene            complement(5324..6601)
                     /gene="yiaN"
                     /locus_tag="OPY25_002810"
     CDS             complement(5324..6601)
                     /gene="yiaN"
                     /locus_tag="OPY25_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HCS0928383.1"
                     /translation="MAVVIFLCCLLGGIAIGLPIAWSLLLCGAALMAYLDMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVIAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPINRSVGLIASGGIIAPIIPPSIPFIIFG
                     VSSGLSISKLFMAGIAPGIMMGAALMLTWWWQAGRLNLPSQPKATPREIWYSLVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVAVVIYRELTFSSLYHVLVNAAKTTS
                     VVMFLVAAAQVSAWLITIAELPMIVSDLLQPLVDSPRLLFIVIMISIMVVGMVMDLTP
                     TVLILTPVLLPLVKEANIDPIYFGVMFIINCSIGLITPPVGNVLNVISGVAKLKFDDA
                     VRGVFPYVVVLMSLLVLFIFIPELIITPLKWIN"
     gene            complement(6604..7077)
                     /gene="yiaM"
                     /locus_tag="OPY25_002811"
     CDS             complement(6604..7077)
                     /gene="yiaM"
                     /locus_tag="OPY25_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HCS0928384.1"
                     /translation="MKRVLEGILAVLIAVLSCIVFINVILRYGFESSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFVVEKLSPANQRRLSLLTHSLILLLCIALGWGSLQK
                     ALQDWSDHSPILGLPIGLMYIACLPTSVAIALIELRRLYHLITRNDSFQQPQQGA"
     gene            complement(7216..8148)
                     /locus_tag="OPY25_002812"
     CDS             complement(7216..8148)
                     /locus_tag="OPY25_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4862 family protein"
                     /protein_id="HCS0928385.1"
                     /translation="MKNNTGYIIGAYPCAPSFHQKSEEEETEFWRQLSDTPDIRGLEQ
                     PCLEHLHPLGDEWLLRHTPGNWQIVVTAIMETMRRRSENGGFGLASSDEEQRKACVEY
                     YRHLHQKINKINGNNTGKVIALELHAAPLAGNPNVAQATDAFARSLKEIANWDWSCDL
                     VLEHCDAMTGPAPRKGFLPLVNVLETIADYDISVCINWARSAIEGRDTSLPLIHTQQA
                     KQAGKLGALMFSGTTLDGEYGEWQDLHAPFAPFCPQSLMTEKHVKELITAAAPELLQF
                     TGIKLLEINASADINHRINILRDGINMMKKATRR"
     gene            complement(8172..8636)
                     /locus_tag="OPY25_002813"
     CDS             complement(8172..8636)
                     /locus_tag="OPY25_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCS0928386.1"
                     /translation="MIFGHIAQPNPCHLPAAIEKALHFLRTTDFRTLEPGVVEIDGKN
                     TFAQIIDMTTRDAAENRPEVHRRYLDIQFLAWGEEKIGVAIDTGNNQISESLLEQRDI
                     IFYHDSEHESFIEMIPGSYALFFPQDVHRPGCNKSIATPIRKIVVKVAIDVL"
     gene            complement(8648..9646)
                     /gene="yiaK"
                     /locus_tag="OPY25_002814"
     CDS             complement(8648..9646)
                     /gene="yiaK"
                     /locus_tag="OPY25_002814"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HCS0928387.1"
                     /translation="MKVTFEELKGAFYRVLRSRNIAEDTADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLDNGDIIPDAKPQRVTSLGAIEQWDAQRAIGNLTAKKMMDRAIELAS
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRELPVDGGFDDNGQLTKEPGVIEKNHRI
                     LPMGYWKGSGLSIVLDMIATLLSNGSSVAEVTQENSDEYGVSQIFIAIEVDKLIDGAT
                     RDAKLQRIMDFITTAERADDNVAIRLPGHEFTKLLDDSRCNGITIDDSVWAKIQAL"
     gene            9876..10676
                     /gene="yiaJ"
                     /locus_tag="OPY25_002815"
     CDS             9876..10676
                     /gene="yiaJ"
                     /locus_tag="OPY25_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HCS0928388.1"
                     /translation="MSQNNDKEKPAGSQSLFRGLMLIEILSNYPNGCPLAHLSELAGL
                     NKSTVHRLLQGLQSCGYVTPAPAAGSYRLTTKFIAVGQKALSSLNIIHVAAPHLEALN
                     LATGETVNFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMGKIYMAFGQPD
                     YVASYWESHKDQIQPLTRNTITDLPAMYDELAQIRETSMAMDREENELGVSCIAVPVF
                     DIHHRVPYAISISLSTSRLKQIGEKNLLKPLRETAQAISNELGFTVRE"
     gene            10793..11266
                     /locus_tag="OPY25_002816"
     CDS             10793..11266
                     /locus_tag="OPY25_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCS0928389.1"
                     /translation="MNRFIMADASACIGCRTCEVACVVSHQEQQNSAAVTTADFVPRI
                     RVIKEDSFTTATVCHQCEDAPCANVCPVQAIRRDRGHIFVTPSRCIGCKSCMLACPFG
                     AMTVVASASGAQAIKCDLCWHREAGPACVEACPTSALQCVDATHVQRQRLYSQPF"
     gene            complement(11303..12553)
                     /gene="avtA"
                     /locus_tag="OPY25_002817"
     CDS             complement(11303..12553)
                     /gene="avtA"
                     /locus_tag="OPY25_002817"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HCS0928390.1"
                     /translation="MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAHIP
                     AMQDYFQTLLTEMVESGKAADALCNYDGPQGKTALLNALAVLLRETLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLEDDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIILCMSLSKLGLPGSRCGIIIANDKTITAIANMNGI
                     ISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQQTIAIIRRYLSEERCLIHK
                     PEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFFPGLDKPWPHTHQCMRMNYV
                     PEPDKIEAGVKILAEEIERAWREG"
     gene            complement(12727..14754)
                     /locus_tag="OPY25_002818"
     CDS             complement(12727..14754)
                     /locus_tag="OPY25_002818"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HCS0928391.1"
                     /translation="MKLAAFALTLIPGIAIASSWTSPGFPTLSTQETGRFTSHAALTK
                     GTRALTLHIDQQCWQPSGAIKLNQMLSLKPCEGAPPQWRLFKDGDYTITVDTRSGTPT
                     LLLSIKTEPERTTQLAYQCPVWDGSPLTLDVRQTFPEGTVVRDYYSGQIDTVQNGKIT
                     LLPADSHGLLLLERAETHASAPFNWRNATVYFVLTDRFRNGDPTNDHSYGRHKDGMQE
                     IGTFHGGDLRGLTSQLDYLQQLGVNALWISSPFEQIHGWVGGGTKGDFPHYAYHGYYT
                     QDWTTLDANMGSEADLRALVDGAHQRGIRILFDVVMNHAGYATLADMQEYQFGALYLS
                     GAERQKILGDRWTNWRPAAGQSWHSFNDYINFSDSAAWEKWWGKKWIRTDIGDYDSPG
                     FDDLTLSLAFLPDIKTESTTPSGLPVFYANKPDTKAKFIEGYTPRDYLTHWLSQWVHD
                     YGIDGFRIDTAKNVELPAWQQLKTQASAALHEWKQANPDKALDDSPFWMTGEAWGHGV
                     MKSDYYRYGFDAMINFDYQEQAAKAVDCLAEMGPVWQQMADKMQDFNVLSYLSSHDTR
                     LFREGGDKAAELLLLSPGAVQIFYGDESARPFGPTGSDPLQGTRSDMNWQDVSGKSAA
                     AVAHWQRISQFRARHPAIGAGQQTTLTLKHGYGFVRQYGDDTVMVVWAGRR"
     gene            15070..15894
                     /locus_tag="OPY25_002819"
     CDS             15070..15894
                     /locus_tag="OPY25_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HCS0928392.1"
                     /translation="MILTPMRRYGAMILMLLTIAFSGEVLAKTRATQTSQKSHITETS
                     YKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITADRNWL
                     ISKQYQNRWSPSERARMKDIAKRYKVSWSGNTRRIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARSNNNLFGMKCTKGRCTNTPGKVKGYSQFASVEESVSAYVANLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTQGARYNNYLFAMYQDNQRLIAAHM"
     gene            complement(15955..17133)
                     /locus_tag="OPY25_002820"
     CDS             complement(15955..17133)
                     /locus_tag="OPY25_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XylR family transcriptional regulator"
                     /protein_id="HCS0928393.1"
                     /translation="MFDKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDNIKEWLGDGVIADYDDDDIAQLLADVDVPIVGVGGSYHLAENYPAVHYIATD
                     NHALVESAFLHLKEKGVNRFAFYGLPDSSRKHWAAEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHVLQACEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLAREEMPLQRILVPPVRVIARRS
                     TDYRSLTDPAVIQAMHFIRNHACKGIKVEQVLDAVGISRSNLEKRFKEEVGETIHALI
                     HAEKLEKARSLLISTTLAINEISQMCGYPSLQYFYSVFKKEYVTTPKEYRDQHSEALL
                     "
     gene            17496..18818
                     /gene="xylA"
                     /locus_tag="OPY25_002821"
     CDS             17496..18818
                     /gene="xylA"
                     /locus_tag="OPY25_002821"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HCS0928394.1"
                     /translation="MQAYFDQLDRVRYEGPQSTNPLAFRHYNPDELVLGKRMEDHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALELAKRKADVAFEFFHKLNVPFYCFHD
                     VDVSPKGASLKEYKNNFAQMVDVLAAKQEQSGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSCAATQVVTAMNATHKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVE
                     HKHKMGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAG
                     HSFHHEIATAIALGIFGSVDANRGDAQLGWDTDQFPISVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALSLKIAARMVEDGELDKRVAKRYAGWNG
                     ELGQQILKGQLSLGELAQYAEQHHLAPVHQSGHQELLENLVNRYLFDK"
     gene            18918..20372
                     /gene="xylB"
                     /locus_tag="OPY25_002822"
     CDS             18918..20372
                     /gene="xylB"
                     /locus_tag="OPY25_002822"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HCS0928395.1"
                     /translation="MYIGIDLGTSGVKAILLNEQGDVLATHTEKLTVSRPHPLWSEQE
                     PEQWWQATDRAVKGLGRQQSLSGVRALGIAGQMHGATLLDSRQQVLRPAILWNDGRCS
                     EECAWLEKQVPQSRAITGNLMMPGFTAPKLVWVQRHEPDIFYQIDKVLLPKDFLRLRM
                     TGVFASDMSDAAGTMWLDVKKRDWSDVMLNACHLTRQQMPALFEGSDITGTLLPEVAS
                     AWGMPAVPVVAGGGDNAAGAVGVGMIDAGQAMLSLGTSGVYFAVSDGFLSKPESAVHS
                     FCHALPERWHLMSVMLSAASCLDWAAKLTGQENVPALIAAAQQADEHADSIWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGVKPASVTL
                     IGGGARSEYWRQMLSDISGLQLDYRTGGDVGPALGAARLAQIAVNKQTPLADVLPQLP
                     LEQAHYPDAQRHAVYQQRRETFRRLYQQLLPLMS"
BASE COUNT         4689 a         5335 c         5633 g         4755 t
ORIGIN      
        1 acatattaat gctcgaatta tccataacat taccgattaa agtccaaaac ggcggattat
       61 ttatttctcg cggcattggg cgtcatcctg ccaggcgtct gcaatcgtgg gaaattatat
      121 ttgtggaaaa aggctgcctg aaaattcagg aagaatgtgt tttctgtgtc gaagccgggg
      181 aaagcctgtt gctttggccg catcgccgcc atattggcgt tgaggagttt cccgccgatc
      241 ttaaatttta ctggctccat tttgaggtca aagcgccgga cagcgacccg cgctggctga
      301 cgcatctttc cgtgccgcag catacccagg ttgccgatcc gcaggcgctg attgcgcttt
      361 ttcgccagtt tatgaacgag caggaaaagc accagcgcag tccggcgctg gagttcatcg
      421 tgctgctgat tttgcagcag ctcaccgttg acgcccggca gaatgaaaac gccgaggccg
      481 ctggcgtgtc gctggcctgg aaagcgcagc agctgattcg aacgcactat cacctgccgc
      541 tttccagcgc ggttctggcg aaagaactgc attgcaatgt ggattatctg ggacgcgttt
      601 atcggcgggt atttcacctt acgctaacgg aagccatcca ccgccagcgg gtgcgcgagg
      661 cggaaaagtt gctgattagc gacgcgcgtt cgttaaaaga ggtggcggag cggtgcggtt
      721 ttaatgacgt tggttacttt cgccagatct tccgcaagca caccggcctg acgcctaccg
      781 cctggaagcg gcgctacagt aaggaacacg ttaattcttg agtataatct ttggccctct
      841 gacaacgcgg ttgcaaactg aatgcccgat ggcgctttgc ttatcgggcc tacaagagtt
      901 catcacaacg tattgatatt gcaaatcttg taggtcggat aaggcgcagc cgccatccga
      961 cacaggctgt gactgccgat attactgccc gtaataggcg ttcgcgccat gtttacgcag
     1021 atagtgttta tcgagcaatt ccggctgcat atccggtagc tgcggggcca gctggcgcga
     1081 gaacagcccc atataggcgc actcctcaag caccacggcg ttgtggacgg catcggcggc
     1141 atttttaccc caggcaaacg ggccgtgtga atgaactaat accgccggga tttgcgccgg
     1201 atcgagaccg cgctcttcaa aggttttaat aatcacctcg ccggtctgat actcgtactc
     1261 gccgttaatt tcctcaacgg tcatcagccg ggtacagggg atcgcgccat agaaatagtc
     1321 ggcgtgggtg gtgccccagg cgggcagatc gagcccggcc tgcgaccaga tcgtcgcatg
     1381 gcgggaatgg gtatgcacga tcccaccgat ctgcggatag cggcgataga gcgccagatg
     1441 ggtcgcggta tcggacgacg gttttttgtt gccttcaacg accttaccgc tggcgatctc
     1501 taccaccacc atatcgtcgg cggtcatcac ctcatattcg acgccggaag gcttaatgac
     1561 catcagcttg cgcgtctcat cgaccgcgct gacgttgccc caggtaaagg tgaccagccc
     1621 gtgcgccggg agggccaggt tggccgccag cacctcggct ttcagttgct ctaacatgtg
     1681 aaacctcctt cctgcatccg tgattcaatc cagcggcggg cctggataat ttccagcacc
     1741 ggctcgctgg ctttctctgt ccacatctca atcagaaatg aaccgcgata gttcagctca
     1801 tgcagcgttt tgaagatgct gacaaaatca acgcatcctt cgccaaacgg cacgtcgcgg
     1861 aactggccgg ggttgtcacc ggtcaccggc agcgtgtctt tcaggtggat cgcggcgata
     1921 cggtcgatac ccagcttcag ctcggcggtc acgtcgttcc cccaggcgct gaggttgccg
     1981 acgtctggat aaacggtgaa ccacggtgac gaaagcatct cgtcccactt tttccacttg
     2041 ctgatggagt tcataaacgc ggtatccatg atctccaccg ccagcatcac ctgcgccgct
     2101 gcggcctgtt ccaccgccca cgccagccct tcggcgaaac gttgctgggt gccttcgtcg
     2161 tgctcttcgt aatagacgtc gtaacctgcc aactggatgg tgcggatccc caggtcgcgc
     2221 gccaggcgaa tggctttggt catgatttca cgcgcccgct ggcgtaccgc ttcgtcgcgg
     2281 ctgccaaaag ggaagcgacg atgggcggag aggcacatcg acgggatggc gacgccgctt
     2341 tccagcatcg cgttcaccag cgaagcgcgt tgggccgagg tccactccag gcgtgagaga
     2401 cgttcgtcgg tttcatccac cgacatctca acaaaatcaa aaccgcagct ttttgccagc
     2461 accagccgct ctggccaact gagatctttc gccagtgctt tctcgtaaat acctaatgga
     2521 tgattacgca tgcttttctc cccaaatggc gtcaatttgg gcgtggaatt cggcggcgac
     2581 ctgcgccgga tgggcggcac ctgccagcgc acgtccggcg ataaatgcct taacgttaat
     2641 gtcgcggaac agcggcagat ccgctggggt aatgccgccg gtaatcgata gttcaaggcc
     2701 gatgtcggac aacgccttca tacgcgccag gtccgcttct ccccactgct gcccgctggc
     2761 ctgcgcatcg tgtccgcggt ggtaaatcgc ctggcgaacc ccgacgcgat accagtctcg
     2821 ggcgtcgtcc agcgtccagt tgccgaacag ttccatttga atttcaccgc cgcaggattg
     2881 cgcgacggca tggcctttct cgacggtcgc gagcggcgcg gcgcagatga tagtcatcca
     2941 gttagcgcca gcgctaaaag cctgctgcgc cagggtttca ccggcatcgg ccactttcca
     3001 gtcggcgacg atgatttttt ccgggcactg cgctcgcagg gctttcaccg cgctaaggcc
     3061 ttcggttaaa caaaggatgg ttccggcctc aacgatatcg acatgatcct gtagcagggc
     3121 gacatcgcgc tgggctgctt ccagactggt gtggtcgagc gccagttgca gtaatggtcg
     3181 gctcataatg cgtgctcctt aatacgggcg tgatagccct gtagtgcttc aatcaaatcc
     3241 tggtattggc ggtatttgcg ctggtagagg gcgtgcgcgg tcatgtccgg cagcagcgtg
     3301 cgtaccgggt gctgcaggtc gcgttgggcc tcgtggaaat cgcgatatac gccggtgccg
     3361 acgcgggctg ccagcgccgc gccgaagcag ccggtctcct ccacctgcgg cagctcgatg
     3421 cgtaacccgc tgacgtccga cagcatctgc atccagacgt cggagtgggc cggtccgccg
     3481 gtaacgcgca gggcgcaaac ctcggtaaag cgttcacgca tgcggttgag gtgggtcata
     3541 tggctgaaga ccacgccttc atagagcgcc tgtagcaggt gcgcgcggtt gtgcagcgcc
     3601 tgcatgccat aaaagccgca ggtcatctcc agcccggcat tgctgccgta gagaaacggg
     3661 agaaaaaaaa ggtcgctacc ggctttcggc aggctggcaa ccgcctggtt gatctcgtca
     3721 aaagagaggt agccccactg ggcggtgaac cattcaaggt tgccggaaga ggtcgggctg
     3781 gcttcgtgaa cgatatactg cccgtcattg acgtagcggc catagacgta aggatgggcc
     3841 tcatggtcgc gcagaccgtg agcgatgccg ctggtgacgg cccaggtccc catcaccgca
     3901 ttgagcgttg attcatcctc aataccggcg caaagggcgg tggaaaccac gtcaaacagg
     3961 ccgccgacga cgggggtacc cgccgccaga ccggtgatag cggccgcctg agcggtgatc
     4021 tccccgcata tttcggctga acccaccacg gggggcagcg cgctatcgat ttcactgatg
     4081 cccagccatt cggtcaggcg cgggtcgtac tggcccgtcg ccatgttgta gaggttggac
     4141 tcggagatat tgctctcctc acagcctttc acgccggtta agcaccagcg cagatagtca
     4201 tgcgtcatca tgacgctgcc tatctgcgcg tagcgctgcg gctcattctc ttttacccag
     4261 cgtaaaaggg agaccggatg cccggtccac agggtttgcc gggtcagtgg gtagagtttt
     4321 tgcggaaccg cttctttttg ccagcgctgg acaatttcca tggcgcgacg atcggaagag
     4381 agtatcgctt tacctaatgg ccgatcgctt ttatctaaca ggaacaggcc tttcccttgg
     4441 gctgaaatac ccagaccgcg gatttgtgag ccgctcaccc ccgtgtgcgt cagcagtttg
     4501 ctgatgaccg aagcgcactg ttgccacagt tcggtcatat cgcgttcaac ccagcctggc
     4561 tgcgggctta aagcgtcgaa tttggcttta ttgatcacca gcagcagagg cgaataggcg
     4621 tgatgagtga gggagaggta tttctgtacc tcatagaatt tcgctgacca cacgacgttg
     4681 atagggtgtt cctgggcatc aatcgtacgg gtttcgaggc cggtatagac ttcggagaat
     4741 ggcatcggaa tagggttcgc gccgaagatt ttaaaggccg cgatattcat tggactgttg
     4801 ttagtgcgga tttttaagcc tttcaaatcg cccggcgttt ttaccggcgc gcgggagttg
     4861 gtgacgtcgc gccagccgtt ttcccagtag gcgaggactt ttaacccttt tgaatcgagt
     4921 gattttttca gttcatcgcc gactttaccg tcgagcgttt tatgcgcatg cgaggtatcg
     4981 cgaaacagga aggggacatc aagtaagttg aatacagggg ccaggccggt gaaattgttc
     5041 gaaccggaca tttccatatc aatagttccg ccgcgcaccc cgctgatcat tgcctgagcg
     5101 ttacctaatg tgctgtcagg aaagagtttt agcgttaatt cgccgttggt tttttctttt
     5161 aataattcgt taaatttttt cgcggcaata tgttgggagt cagtttgcgg tgtttcataa
     5221 ccaaaacgta aagattgcgc cgccagagac gacacgctga aaaccgtcag accagctatc
     5281 aataatgaac gagcaataac gtgtaatttc ataatattat cctttaatta atccatttaa
     5341 gcggtgtgat aattagctcg ggaataaaaa taaataaaac cagcagcgac atcagtacga
     5401 caacgtaagg gaatacgcct cttaccgcgt catcaaattt caattttgct accccggaaa
     5461 taacgttgag gacgttgcca acgggcggtg tgattaatcc aatagagcag ttaataatga
     5521 acatgacgcc gaaataaatc gggtcaatat tggcttcttt aactaatggc aataatacag
     5581 gggtaagaat taacaccgtt ggcgtcaaat ccatcaccat accgacgacc ataattgaga
     5641 tcataatgac gataaataag agtcgcggag agtcgaccag cggctgcagc aaatctgaca
     5701 ctatcatggg taattccgcg atcgtaatca gccaggcgga tacctgggcc gcggccacca
     5761 gaaacatgac gactgacgtc gttttggcgg cattgaccag cacgtggtag agactggaaa
     5821 acgttaattc ccgatagata accacggcga caaagagggc gtaaaacgcg gcgaccgccc
     5881 ctgcctccgt tggcgtgaaa agtccggaac ggaagccgcc gatgataatc accggtaaaa
     5941 acagcgccca gatacctgaa accaatgaat accagatttc acgcggtgtt gctttaggct
     6001 gagaagggag atttaatcgc ccggcctgcc accaccaggt gagcataagt gccgcgccca
     6061 tcatgatgcc cggtgcgatc ccggccataa acagcttgct gatcgacaag ccgctggaaa
     6121 cgccgaagat aataaaagga atcgaggggg gaataattgg cgcaatgatc ccgccggaag
     6181 cgattaaccc aacggagcgg ttgatcgggt agtttgcgga gcgcatcatc ggcaccagca
     6241 gcgcggcgac cgcagcggta tctgctaccg cagagccgga aaggctggcc ataatcattg
     6301 ccgcaataac gcccacgtag cccaggccgc cgggcttatg gccgaccagc ttcatcggca
     6361 ggtcgacaat tcgctttgac aggccgcccg cgttcatgat ttcaccggcc aaaacaaaaa
     6421 agggaatggc cagtagggag aaactgtccg cgccgttaac cagggtttgc gccataatct
     6481 gcacgtcaaa catatccagg tatgccatca gagcagcgcc gcaaagcagc agcgaccagg
     6541 cgatgggtaa acctatcgcg atcccgccga gcaggcagca gagaaatatc accacggcca
     6601 tgattaggct ccttgctgtg gttgttgaaa ggaatcgtta cgcgttatta agtgataaag
     6661 ccgacgcagc tcgattaacg cgatggcaac gcttgtgggc agacaggcga tatacatcag
     6721 gccgatcggt aaaccgagga ttggcgagtg atcgctccag tcctgcaacg ctttttgcag
     6781 gctgccccag cctaatgcga tgcataacaa taaaatcagc gaatgtgtca gcagcgagag
     6841 tcgacgctga ttcgctggcg aaagtttttc caccacaaaa gtgacctgaa cgtgagcgtt
     6901 atccataaat gcaacgatgg cgccaataaa cgtcagccat acaaatagat aacgtgatag
     6961 ttcatctacc gacaaaatac tgctctcaaa accgtaacgt aaaataacgt taataaatac
     7021 aatgcaggaa agtacggcaa ttaataccgc aagtatgccc tcaagtaccc gcttcataac
     7081 gactccatca ggttatagaa acttatttct ttcgatgctg aatagtggaa cttaatttct
     7141 tatgtttggt ttatattagg tcggcgcaac gttgagttgc aggccgagaa ttaaggtgat
     7201 gatgtttaat tcaggttagc ggcgtgtggc ctttttcatc atgttaatac catcgcgtaa
     7261 tatatttatg cggtgattaa tatcggcact ggcattgatt tccaacaatt taataccggt
     7321 aaactgcaac agttcgggag cggcggcggt aatcagttct ttaacatgtt tctccgtcat
     7381 cagactttgt ggacagaaag gtgcaaacgg agcatggagg tcctgccatt cgccgtattc
     7441 tccatccagc gttgtaccgg agaacatcag cgccccgagt tttccagcct gtttggcctg
     7501 ctgcgtgtgg atcagcggta gagaggtatc ccgcccttca atagccgagc gcgcccagtt
     7561 aatgcagacg cttatgtcat agtcggcaat agtttccagt acgtttacca acggtaagaa
     7621 tcctttgcgc ggtgcggggc cggtcatcgc gtcgcagtgt tcaagcacca ggtcgcagga
     7681 ccagtcccag ttggcaatct cttttaatga gcgcgcaaag gcgtcggttg cctgcgccac
     7741 gttcggattg cccgccagag gagcggcatg aagctcaagg gctatgactt tgccggtatt
     7801 gttcccattg attttattga tcttctgatg cagatgacga tagtactcca cgcaggcttt
     7861 acgctgttcc tcgtcactgg acgctaatcc aaaaccgccg ttttcgctac ggcgacgcat
     7921 ggtttccatt atcgcggtga ccacgatttg ccagtttccc ggtgtatggc gcaataacca
     7981 ctcgtcgccg agcgggtgaa gatgttcaag acaaggctgc tccagccccc ggatatccgg
     8041 agtatcagag agttgccgcc agaattccgt ctcttcctct tcactcttct ggtgaaatga
     8101 gggtgcacaa gggtacgcac cgataatata accggtatta tttttcattt tgtgctccag
     8161 taaactctat tttataaaac gtctatggcg acttttacga ctattttccg tatcggcgta
     8221 gcaatgcttt tattacaacc gggacgatga acatcctgcg ggaaaaacag ggcataactt
     8281 cccggtatca tttcaatgaa tgattcatgt tcactgtcgt gataaaaaat aatatcgcgc
     8341 tgttctaata atgactcgct gatttgatta ttaccggtat caatggcaac cccaattttc
     8401 tcttcacccc atgccagaaa ctgaatatcc agatagcggc gatggacttc cggacgattt
     8461 tcagcagcat cgcgggtggt catatcgata atctgcgcga aggtattttt gccgtcgatt
     8521 tccactacgc cgggttccag cgtgcgaaag tcggtggtac gtaaaaagtg aagcgctttc
     8581 tcgatcgcgg ctggcaaatg acatggattt ggctgcgcga tatgtccaaa aatcatgatg
     8641 tggctcctta cagcgcctgg attttagccc agacgctgtc gtcaatggtg ataccgttac
     8701 agcggctgtc atccagcaat ttggtaaatt cgtggccggg cagccgaatc gcgacgttgt
     8761 cgtcagcacg ttcagcagtg gtgatgaaat ccataatccg ctgcagtttg gcatcgcggg
     8821 ttgcgccatc gatcagctta tccacttcta tggcgatgaa aatctgcgaa acgccatact
     8881 catcgctgtt ttcctgggtc acttcggcaa cggaagagcc gttggaaagc agggtggcaa
     8941 tcatgtccag cacaatcgac agaccagatc ctttccagta acccatcggt aaaatgcggt
     9001 gatttttctc gatcacgccc ggttctttgg tcaactgacc gttatcgtcg aaaccgccgt
     9061 ccaccggcag ttcgcggccc gccagacggt taacttctaa catcccgtag gagaacatcg
     9121 acatcgacat atctaccatc gtgatcggcg tagacgggat ggcgacgatc agcggattgg
     9181 taccgatacg gcactctttc gcgccccacg gcggcatgac ggcgatggag ttggtccagc
     9241 aaatgccgat atagcctttt tccgccgcct gccagccgta gctgccgccg cgcatccagt
     9301 ggttagcatt acgtaacgcc accaggccaa taccatgatc ggaagccagc tcgatggccc
     9361 ggtccatcat ctttttcgcc gtcaggttgc cgatagcgcg ctgagcatcc cactgttcga
     9421 tggcgccgag gctggtaacc cgctgcggtt tagcatcagg aataatgtcg ccgttatcca
     9481 gttgctggat gaagcgggga aagcggttca cgccgtggga atagacaccg gactcggtgg
     9541 tgcgagcgaa catttccgcg caggcgtcgg cggtatcttc cgcaatattc cgcgaccgca
     9601 agacgcggta gaaggcccct tttaactctt cgaaagttac tttcatccct gttctcctgg
     9661 tcgattgtta gaaattttag tatgtttttt tgtcgataaa tttcataatg cgaaatgtag
     9721 ttccaaatat atagatcaaa aattgacatg gcaacgccag agaagctttt taaaaacgat
     9781 taaaatcatc gggttatgtt ttttatgctg atatcgtgaa ctgcaacaca ctttgagcta
     9841 ccatctgatc gcccaagaaa ggagagagtt ttctgatgag ccagaacaac gataaagaga
     9901 agcctgcggg gagtcagagc ctgtttcgtg gcctgatgtt gatagaaatt ttgagtaact
     9961 acccgaacgg ttgcccactg gcgcacctgt cggagctggc ggggttgaac aagagtaccg
    10021 tccatcgttt gttgcagggg cttcaatcct gcggatacgt gacgccagcg ccggcggccg
    10081 gaagctaccg tctgacgaca aagtttattg ccgtcggcca aaaagccctg tcatcgctga
    10141 atatcatcca cgttgcggca ccgcaccttg aggcgctcaa cctggccacc ggcgagacgg
    10201 tgaatttttc cagccgtgaa gatgatcacg ctatcctgat ttataagctg gaaccgacca
    10261 ccggtatgct gcgcacgcgt gcctacattg gccagcatat gccgctgtac tgctcggcga
    10321 tggggaaaat ttatatggcg tttggtcagc cggattatgt ggcgtcttac tgggaaagcc
    10381 ataaagatca gatccagccg ctgactcgta ataccattac cgatttacca gcaatgtacg
    10441 atgagctggc gcaaattcgt gaaaccagca tggcgatgga tcgcgaagaa aatgaactgg
    10501 gcgtttcctg tattgctgtg cctgtgtttg atattcacca tcgagtgcct tacgccattt
    10561 ctatttcact gtcgacgtca cggctaaaac agatcggcga gaaaaatctg ctcaaaccgt
    10621 tgcgtgaaac cgcacaggct atctctaatg agctgggatt taccgttcgc gaataagaca
    10681 gctcgccagg ttttatcagg catctgacaa aatttgtccg tttgcgtagt gggatcaaag
    10741 cggcggggaa tggctctctg gcattctggc gttttaacgc agggggagaa caatgaaccg
    10801 gtttattatg gcggatgcgt cggcgtgtat cgggtgtcgt acctgcgagg tcgcctgcgt
    10861 ggtgtcgcac caggaacagc agaatagcgc ggcggtgacg acggcggact ttgtgccgcg
    10921 tatccgggtg ataaaagagg atagcttcac cacggccacg gtctgccatc agtgtgagga
    10981 cgcgccgtgc gcgaatgtct gcccggtaca ggcgattcgc cgtgatcggg ggcatatctt
    11041 cgtgacgcca tcgcgctgca ttggttgtaa aagctgtatg ctggcttgcc cgtttggcgc
    11101 gatgactgtg gtggcgtccg cgtcaggcgc gcaggcgatt aaatgcgatc tttgctggca
    11161 tcgggaagcg gggccggcgt gcgtggaagc ctgcccgacc agtgcgttac agtgcgttga
    11221 cgcaacacac gtgcagcgcc agcgcctcta ttctcaacct ttctgaacat cgttccggcc
    11281 tgcataatgg ccggaataac cgtcagcctt cacgccaggc gcgttctatc tcttctgcca
    11341 gaatttttac gcccgcctcg attttatccg gttcaggcac gtagttcatc cgcatacact
    11401 ggtgtgtgtg cggccagggt ttatccagtc cgggaaagaa atagtggccc ggcaccatca
    11461 gcacgccgcg cgctttcaag cgttgataga gtagctcggt ggtaatcggc agatctttaa
    11521 accacagcca caaaaatatt gcgccttctg gtttatgaat caggcagcgt tcttcggata
    11581 aatagcgacg aatgatcgcg atcgtctgtt gaacgcgctg atagtagaaa ggtttgataa
    11641 ccgtttccga cagccgcagc agatcgttac gcttaatcat ttcgcacatc atcgccgggc
    11701 ccatgccccc gggcgcaagg ctgatgatgc cgttcatgtt ggcaatggcg gtaatcgtct
    11761 tatcattggc gatgataatc ccgcagcggg aaccgggcag ccccagcttt gagaggctca
    11821 tgcataggat aatattgggg ttccacagcg ggcgcgcctc gctaaagata atgcccggaa
    11881 acggtacacc gtaagcgtta tcaatcacca gtgggatgtt gtgctgattc gccagtctgt
    11941 ccagcttcat cagctcttcg tcggtgataa cgttaccggt tgggttggtc gggcgcgaga
    12001 cgcaaatcat ccccgtttct tcgccgatgt gcagatgctc aaaatcgacg tgatacttaa
    12061 actggccttc cggcagcagc tcaatattcg ggcgcgccga aacgaagagg tcgtcttcca
    12121 gaccggaatc cgcatagccg atgtattccg gcgcaagcgg gaatagtacc tttttcgtac
    12181 tgccgtcggc gcgacgtccg gcgaagagat taaataagta gaaaaacgcg ctctgactgc
    12241 catttgttag cgcaatattc tgtggttcga tatcccatcc cagcgtttca cgtagcagta
    12301 cggccagtgc attcagtagc gccgtttttc cctggggacc gtcataatta caaagcgcat
    12361 cagcggcttt gccgctttct accatctctg tcagtagcgt ctggaaataa tcctgcattg
    12421 cagggatgtg tgccgggtta ccgccgccaa gcatgatggc gcctggcgtg cgtaagccgt
    12481 cgttgagatc ctccatcagg cgggtaatgc ctgaatggcg ggtaaattta tcgccgaaaa
    12541 gtgaaaatgt cataacgggt gatctatcga actgtctgtc aaagtggata accataacgc
    12601 tacaaatggc ggggcgcaaa tgggggacag gcggtggtat tgatgtttta tgctacaaat
    12661 ttttatcagt ttagtttttt attttgaaga ggttaccggt acgcgagggg accggtagcg
    12721 ccacgattag cggcggcccg cccagacgac catcaccgta tcgtcgccgt actggcgtac
    12781 aaaaccgtac ccgtgtttta gcgtcagcgt ggtttgttgg cctgcgccga tggcgggatg
    12841 tctggcgcgg aactggctaa tacgctgcca gtgcgcgacg gctgcggctg actttccgct
    12901 cacgtcctgc cagttcatat cagaacgggt gccttgcagc gggtcggagc cggtggggcc
    12961 gaagggacga gcggattcat cgccgtaaaa gatctgcacc gcgcctggcg aaagcagcag
    13021 cagttccgcc gccttatcac cgccctcacg gaaaaggcgc gtatcatgcg aggagaggta
    13081 acttaatacg ttgaaatcct gcattttatc cgccatctgc tgccagactg gccccatttc
    13141 cgccaggcaa tcgaccgctt tcgccgcctg ctcctgataa tcaaaattga tcatcgcgtc
    13201 gaaaccatag cgataataat cacttttcat gacgccgtgg ccccacgctt cgccagtcat
    13261 ccagaacggg ctatcatcca gcgctttgtc cggattggcc tgcttccatt catgtaacgc
    13321 cgcgctggcc tgggttttta gctgttgcca ggcaggaagc tcaacgtttt tggcagtatc
    13381 gatccggaac ccgtcaatgc cgtaatcatg cacccactgg cttaaccagt gagtcagata
    13441 atcccgtggc gtatagccct caatgaactt tgctttagta tcgggtttgt tggcatagaa
    13501 cacgggtagg ccggaaggcg tggtagattc cgtttttata tccggcagga aggccagcga
    13561 cagggttaaa tcgtcaaatc ccggactgtc gtagtcgcca atatcggtac gaatccactt
    13621 tttcccccac catttttccc aggcggcgct gtcgctgaag ttgatgtagt cgttaaagct
    13681 gtgccagctt tgtccggcgg ccggtcgcca gtttgtccag cgatcgccga gaattttttg
    13741 ccgttccgcg ccggataaat agagcgcgcc gaactgatac tcctgcatat ccgccagcgt
    13801 ggcgtaaccg gcatgattca ttactacgtc aaataaaata cggatgccgc gctggtgcgc
    13861 gccgtcgacc agcgcgcgga gatcggcttc gctgcccata ttggcatcca gcgtcgtcca
    13921 gtcctgagtg taatagccgt gataggcgta atgaggaaaa tcgccttttg ttccgccgcc
    13981 gacccagccg tggatctgtt caaacggcga gcttatccac aaggcgttca cgcctaattg
    14041 ctgtagatag tccagttgac tcgtcaaccc gcgcaaatcg ccgccgtgga aagtgccaat
    14101 ctcttgcata ccatccttat ggcgaccata actgtggtcg ttggttggat cgccattgcg
    14161 aaagcgatcc gtaagcacaa aataaacggt ggcgttgcgc cagttaaaag gcgctgacgc
    14221 atgggtttcc gcgcgttcca gcaataaaag cccgtggctg tcggcaggta gcagcgtgat
    14281 ttttccgttt tggacggtat cgatttgacc actgtaataa tcgcgcacta ccgtcccttc
    14341 cggaaaggtt tggcgaacat ccagcgtgag cggcgaacca tcccagacgg gacactggta
    14401 ggcgagctgc gtggtgcgtt caggttcagt ttttatcgat aacaacaggg tcggcgtacc
    14461 ggatcgggta tctaccgtta tcgtatagtc gccatcttta aacagacgcc attgcggcgg
    14521 cgcgccttcg cagggtttta acgacaacat ttggttgagt tttatagcgc cggagggctg
    14581 ccagcactgc tggtcaatat ggagcgttaa cgcgcgtgta ccttttgtta atgcagcatg
    14641 gctggtaaag cgtccggttt cctgcgtcga gagcgtcgga aaaccgggcg aggtccatga
    14701 tgaggcgatc gcgataccgg gtatcagcgt cagagcgaag gcggcaagtt tcatcacgct
    14761 atcctttgtg ggcaatattc atcagcttgc ctggttttta ggcgaatgaa ctcctcccca
    14821 gcagagagtc gcgcaggagg aggcgcgagg gtgagcgacg aggcgcaaaa aaacgcctct
    14881 atttgcgata aacgccgcat tttattggca ttattgctgt ctgttatcgt taatagttga
    14941 catagtttcg gattaagact attccctgag gtgcttttta agcctatttt tgctagaatt
    15001 tggggttcaa acctcaactt cgtgaaaaat aaaaggtgtt ggaatgtatc aatccgacca
    15061 ggagacctaa tgatattgac tcccatgcga cgatatgggg caatgattct tatgttactc
    15121 accatcgcat tttcgggtga ggtgctggca aagacgcgcg caacacaaac gagtcaaaag
    15181 tcccacataa ctgagacaag ttataaacag gttagcagta aacaagagta ttctcgcaat
    15241 agtgcaaaga gcagttcact tcctgatttg cgaaaatacc cttccggaac ccccagaaaa
    15301 aaagcgtttc tccggaccgt tatgccttac atcaccagcc aaaatgccgc gattaccgcg
    15361 gaccgtaatt ggctgatctc aaaacagtac cagaaccgct ggtcgccgtc tgagcgcgcg
    15421 cgtatgaaag atatcgcgaa gcgctataaa gtgagctggt ccggcaacac gcgtcgtatt
    15481 ccgtggaata cgttgctgga gcgcgtcgac attatcccaa ccagcatggt ggcgacgatg
    15541 gcggcggcgg aaagcggctg gggaacctct aaactggcgc gtagcaacaa taacctgttc
    15601 ggcatgaagt gcacgaaagg gcgttgtacc aatacgccgg gtaaggtgaa aggttactcg
    15661 caattcgcgt cggttgagga gtcggtgagc gcgtatgtcg ccaacctgaa cacgcatccg
    15721 gcttattctt ctttccgcaa gtcgcgcgcc caactgcgta aggcggatca ggaagtcacc
    15781 gccacggcga tgattcataa gctaaagggt tactctaccc agggggcgcg ctataacaac
    15841 tacttgttcg cgatgtacca ggacaaccag cgtctgatcg ccgcgcatat gtaattctgt
    15901 gtgccggatg gcgctacgct atccggctta caaggcatct gtaggctgga taaactacaa
    15961 caacgcttca ctatgctggt cgcgatactc cttaggcgta gtgacgtact cctttttaaa
    16021 caccgaatag aaatattgca gcgacgggta gccgcacatt tgcgaaattt cgtttatcgc
    16081 caacgtggtg gaaatcaaca aactacgcgc tttttccagc ttttcggcgt ggatcagcgc
    16141 atgtatcgtc tcgccaactt cttccttaaa acgtttttcc aggtttgaac gtgaaatccc
    16201 aaccgcgtcc agcacctgct cgactttaat gcccttacag gcatggttac gaataaagtg
    16261 catcgcctgg ataaccgccg gatcggtcag ggagcgatag tctgtcgagc ggcgcgcaat
    16321 gacgcgcacc ggcggcacca gaatgcgctg taacggcatc tcttcgcgcg ccagcaaacg
    16381 gtgcagcagc ttcgccgcct gatagcccat ttgccgcgcc ccctgcgcga cggaggaaag
    16441 cgcgacgcgc gacagataac gggttaactc ttcgttatca ataccgataa cgcaaagttt
    16501 ttccggcacc ggaatatgca ggtgttcgca ggcctgcaat acgtgacggg cgcgggcatc
    16561 cgttacggca atgatgccgg tttgcggcgg cagcgtctga agccagtcgg cgaggcgatt
    16621 ttgcgcgtgc tgccagtttt ccggcgcggt ttccagcccc tgatagacta cgccgcggta
    16681 tttttcctcg gcgaccagct ggcgaaaggc gtattcccgt tccgccgccc aatgtttgcg
    16741 gctggagtcg ggcaaaccgt aaaacgcgaa gcggttaacg cctttttctt ttaaatgcag
    16801 gaaagcgctt tcaacgagcg catgattatc ggtggcgatg taatgaacgg cgggataatt
    16861 ttcagcaaga tggtaagaac cgccgacccc gacaatgggt acgtcgacat cggccaataa
    16921 ttgcgcgata tcgtcatcat cgtaatcggc aataacgccg tcgcctaacc actctttaat
    16981 gttatcgata cgggcacgga aatcttcctc aataaatata tcccattcgg attgcgaggc
    17041 ttgtaaatat tcacccaccc cctccactac ctgacggtca taggctttat tcgcgttaaa
    17101 taacagagtg atacggtgac gtttatcaaa catgaggata tatcctgcaa aagtgaacct
    17161 ggactcatgg atactatcaa aacggctgac ataacggtct ggcgaatgat gacaaattat
    17221 tttgcgcctg aaacgttatg cgaaattcat cacagcaaac ggcggatgac aattgtcatt
    17281 tcttatctat atattacggt tttttgttta tttgccagga ttcgatcgcg atcgcttttt
    17341 tcttctgtgg ttttcagcgt ttttttgaga gccagagcac atttggggat tctcttaata
    17401 gcggtgtgaa ataacgtaat tgagcaataa atcaggaaat tccagtatga cgttatgtcg
    17461 tttacttgcc gtcttatctg attatggagc tcactatgca ggcttatttt gaccaactcg
    17521 atcgtgttcg ctatgaaggc cctcaatcga ctaacccgct ggcatttcgt cattacaatc
    17581 ccgacgagct ggttttaggt aaacgtatgg aagatcacct gcgtttcgcg gcctgttact
    17641 ggcatacctt ctgctggaac ggcgcggata tgtttggcgt aggcgcgttt aatcgtccgt
    17701 ggcagcaacc gggcgaagcg ctggagctgg cgaaacgcaa agcggacgtg gcgtttgaat
    17761 ttttccacaa actgaatgtg cctttttact gcttccatga cgtggatgtg tcgccgaaag
    17821 gcgcgtcgtt gaaagaatat aaaaacaact tcgcgcagat ggtggatgtg ctggcggcga
    17881 aacaggagca gagcggcgta aaactgctgt ggggaacggc gaactgcttt accaacccgc
    17941 gctatggcgc aggcgccgcc actaacccgg acccggaagt ctttagctgt gcagcgacgc
    18001 aagtggttac ggcaatgaac gccacgcata aactgggcgg cgaaaattac gtactgtggg
    18061 gcggacgcga aggttatgaa acgttgctga ataccgatct acgccaggaa cgcgaacaga
    18121 ttggccgctt tatgcaaatg gtggttgagc acaaacataa aatgggtttc cagggcacgc
    18181 tgctgattga accgaaaccg caggaaccga caaaacatca gtatgattat gacgttgcaa
    18241 cggtctatgg cttcctcaaa cagttcggcc tggaaaaaga gatcaaagtg aacattgagg
    18301 cgaaccacgc cacgctggcg ggccattcgt tccaccatga aatcgcaacc gctatcgcgc
    18361 tgggtatttt tggctccgtt gatgccaacc gcggcgatgc gcaactgggc tgggataccg
    18421 atcagttccc gattagcgtt gaagagaacg cgctggtgat gtacgaaatc ctgaaagcgg
    18481 gcggattcac gacgggcggt ctcaacttcg acgccaaagt tcgtcgccag agcaccgata
    18541 aatacgatct gttctacggt catatcggcg cgatggatac gatggcgttg tcactgaaaa
    18601 tcgccgcgcg tatggtcgaa gacggcgagt tggataaacg cgtggcgaag cgctatgccg
    18661 gctggaatgg cgagctgggg cagcagattc tgaaaggaca actctcctta ggcgaactgg
    18721 cgcagtatgc ggagcagcac catctggcgc cggtacatca aagcggtcat caggagctgt
    18781 tagaaaatct ggttaaccgt tatctgtttg ataaataact ctatctaccg ggcgactccg
    18841 cgttagcccg gcctgtagtc gtgattagcc cggtaagcgt agcgctgccg ggcgctttca
    18901 gtaaaggaac ccacactatg tatatcggga tcgatcttgg tacatcgggt gtaaaagcta
    18961 tcctgttgaa tgagcagggc gatgtgctgg ctacgcatac tgaaaaactg accgtatcgc
    19021 gtccgcatcc cttatggtcg gaacaggaac cagagcagtg gtggcaggcg acggatcgtg
    19081 cggttaaagg tttaggtcgg caacagtcgt taagtggcgt ccgggcgttg ggcatcgccg
    19141 gacaaatgca tggcgcgaca ttacttgata gccgtcagca ggttctgcga ccagcgattt
    19201 tatggaatga cggacgctgt agcgaagagt gcgcctggct ggaaaaacag gtgccgcagt
    19261 cgcgagcgat aaccggtaat ctgatgatgc ccggttttac cgcgcccaaa ttagtttggg
    19321 tgcagcgcca cgaaccggat attttctacc agatagacaa ggttctgctg ccgaaagatt
    19381 ttctgcggct gcgaatgaca ggcgtctttg ccagcgatat gtcggatgcg gcgggaacga
    19441 tgtggctgga cgtgaaaaag cgcgactgga gcgacgttat gctcaacgcc tgtcatttaa
    19501 cccgacagca gatgccagcg ttatttgaag gtagtgacat taccggaacg ttgctgccag
    19561 aggtcgccag cgcatgggga atgccagcag tacctgtggt ggcaggcggc ggcgacaatg
    19621 cggctggcgc ggtcggcgta ggaatgatcg atgccggaca ggcgatgctc tcactcggaa
    19681 catcgggcgt ctattttgcc gtcagcgacg gctttctgag taaaccggag agcgcagtac
    19741 acagtttttg ccatgcgctg ccggaacgct ggcatttaat gtctgtgatg ttgagcgccg
    19801 cctcttgtct ggactgggcg gctaaactca ccgggcagga gaacgtcccg gcgctgattg
    19861 ccgccgcaca gcaggcggat gagcatgccg attcgatctg gtttttgccg tacctgtccg
    19921 gcgagcgcac gccgcataat aatccgcagg caaaaggcgt tttctttggt ttaacccatc
    19981 agcatggccc ggcggaactg gcgcgggcgg tactggaagg cgtgggatat gctttggcgg
    20041 acggtatgga tgtggttcac gcctgcggcg tcaaacccgc cagcgtgacg cttatcggcg
    20101 gcggagcgcg cagcgaatac tggcgtcaga tgctatctga tattagcggg ctacagcttg
    20161 attatcgtac tggcggcgat gtagggccag cgctgggcgc ggcgcgtctg gcgcaaattg
    20221 cggtgaataa acagactccg ctcgccgatg tattgccgca gttgccgctg gagcaggcgc
    20281 attatcctga tgcgcagcgt catgcggttt atcaacaacg tcgtgaaacc ttccgtcgac
    20341 tctatcagca gctgttgccg ttgatgtcat aagtcagaat gcctttcagt tttggctgaa
    20401 aggcatttcc cg
//
LOCUS       DAJVKX010000075        20302 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000075 DAJVKX010000000
VERSION     DAJVKX010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20302
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.075"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..1237
                     /locus_tag="OPY25_002823"
     CDS             <1..1237
                     /locus_tag="OPY25_002823"
                     /EC_number="2.7.8.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="undecaprenyl-phosphate galactose
                     phosphotransferase"
                     /protein_id="HCS0928396.1"
                     /translation="CVGWFWIRLRHYTYRKPFWYELKEIFRTIVIFAIFDLALIAFTK
                     WQFSRYVWVFCWTFAIILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARGAYSALQS
                     EEMMGFDVIAFFDTDASDAEINMLPVIKDTGTIWDLNRTGDVHYILAYEYTELEKTHF
                     WLRELSKHHCRSVSVVPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSSRFLKRTF
                     DIVCSIIILIIASPLMIYLWYKVTRDGGPAIYGHQRVGRHGKLFPCYKFRSMVMNSQE
                     VLKELLANDPIARAEWEKDFKLKNDPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVG
                     PRPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRNDVDYDTRVYFDSWYVKNWTLWN
                     DIAILFKTAKVVLRRDGAY"
     gene            1401..2807
                     /gene="gndA"
                     /locus_tag="OPY25_002824"
     CDS             1401..2807
                     /gene="gndA"
                     /locus_tag="OPY25_002824"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCS0928397.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLEKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKDAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELANT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLIDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKAQRVAASKVLSGPKAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYHWELNYGEIAKIFRAGCIIRAQFLQKITDAYAENAGIANLLLAPY
                     FKKIADEYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRTDKEGIFHTEWLE"
     gene            3044..4210
                     /gene="ugd"
                     /locus_tag="OPY25_002825"
     CDS             3044..4210
                     /gene="ugd"
                     /locus_tag="OPY25_002825"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HCS0928398.1"
                     /translation="MKITISGTGYVGLSNGLLIAQHHDVVALDIVPARVELLNDRISP
                     IVDKEIQQFLKEDNIRFRATLDKFDAYQNADYVIIATPTDYDPKTNYFNTFSVESVIQ
                     DVISINPAAVMIIKSTVPVGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVI
                     GEQSERAREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ETLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAI
                     VEANRTRKDFIADSILARKPKVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMQEETFFNSRLERDLHCFKQQADVIISNRMAAELLDVAEKVYTRDLFGSD"
     gene            4352..5335
                     /gene="wzzB"
                     /locus_tag="OPY25_002826"
     CDS             4352..5335
                     /gene="wzzB"
                     /locus_tag="OPY25_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen chain length determinant protein
                     WzzB"
                     /protein_id="HCS0928399.1"
                     /translation="MTVDSNASSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILL
                     AVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVLYGGNAPKISEVQANFISRFSSA
                     FSALSEALDNQKEREKLTIEQSVKGQTLPLSVSYVSTTAEGAQRRLAEYIQQVDEEVA
                     KELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQ
                     QTQDVTQDTMFLLGSDALKSMIQNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHV
                     YRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALRSYKPKAL"
     gene            complement(5416..6027)
                     /locus_tag="OPY25_002827"
     CDS             complement(5416..6027)
                     /locus_tag="OPY25_002827"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HCS0928400.1"
                     /translation="MLTEQQRRELDWEKTDGLMPAIVQHAVSGEVLTLGYMNPQALDK
                     TIESGHVTFFSRTKQRLWTKGETSGHVLNVVSIAPDCDNDTLLVLANPVGPTCHKGTS
                     SCFGDASHQWLFLYQLEQLLAERKTADPASSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVNDRFELTNEASDLMYHLLVLLQDQDLNLTTVIDDLRKRHQ"
     gene            complement(6021..6797)
                     /gene="hisF"
                     /locus_tag="OPY25_002828"
     CDS             complement(6021..6797)
                     /gene="hisF"
                     /locus_tag="OPY25_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HCS0928401.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGA
                     DELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIRSIDDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWFDDATGKYHVNQYTGDENRTRVTQWETL
                     DWVQEVQQRGAGEIVLNMMNQDGVRNGYDLTQLKKVRDVCRVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLAGQGVEIRIC"
     gene            complement(6779..7516)
                     /gene="hisA"
                     /locus_tag="OPY25_002829"
     CDS             complement(6779..7516)
                     /gene="hisA"
                     /locus_tag="OPY25_002829"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HCS0928402.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYARQRDYGNDPLPRLQDYAAQGAG
                     VLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEEDVAALLKAGVARVVIG
                     STAVKSPDVVKGWFERFGAQALVLALDVRIDEHGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEICARYPQIAFQSSGGIGDIDDIAALRGTG
                     VRGVIVGRALLEGKFTVKEAIQCWQNV"
     gene            complement(7516..8106)
                     /gene="hisH"
                     /locus_tag="OPY25_002830"
     CDS             complement(7516..8106)
                     /gene="hisH"
                     /locus_tag="OPY25_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HCS0928403.1"
                     /translation="MNVVILDTGCANLSSVKSAVARHGYTPVVSREAEIVLRADKLFL
                     PGVGTAQAAMDQLRERELIDLIKACTQPVLGICLGMQLLGRRSEETRGVDLLNIIEQD
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFFGVQFHPERSGAAGAQLLKNFLEM"
     gene            complement(8106..9173)
                     /gene="hisB"
                     /locus_tag="OPY25_002831"
     CDS             complement(8106..9173)
                     /gene="hisB"
                     /locus_tag="OPY25_002831"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HCS0928404.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDHFDKLAFEPEVIPVLLKLQ
                     KAGFKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVCFDEVLICPHLPADDCD
                     CRKPKVKLVERYLAEQAMDSANSYVIGDRATDIQLADNMGITGLRYHRETLNWTMIGE
                     QLTKRDRYAHVVRNTKETQIDVSVWLDREGNSKINTGVGFFDHMLDQIATHGGFRMEI
                     TVKGDLYIDDHHTVEDTGLALGEALKLALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            complement(9170..10249)
                     /gene="hisC"
                     /locus_tag="OPY25_002832"
     CDS             complement(9170..10249)
                     /gene="hisC"
                     /locus_tag="OPY25_002832"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HCS0928405.1"
                     /translation="MSTENTLSVADLARENVRNLVPYQSARRLGGNGDVWLNANEFPT
                     AVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELVIRAFCEPG
                     KDAILYCPPTYGMYSVSAETIGVERRTVPALENWQLDLQGISDNLDGAKVVFVCSPNN
                     PTGQLINPQDLRTLLELTRGKAIVVADEAYIEFCPQATLAGWLVKYPHLVILRTLSKA
                     FALAGLRCGFTLANEEVINLLLKVIAPYPLSTPVADIAAQALSPQGINVMRDRVAQTV
                     QERQYLVNALQQTACVEHVFDSETNYILARFTASSSVFKSLWDQGIILRDQNKQPSLS
                     GCLRITVGTRQENQRVIDALRAEPV"
     gene            complement(10246..11550)
                     /gene="hisD"
                     /locus_tag="OPY25_002833"
     CDS             complement(10246..11550)
                     /gene="hisD"
                     /locus_tag="OPY25_002833"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HCS0928406.1"
                     /translation="MSFNTLIDWNSCSPEQQRALLTRPAISASDSITRTVSDILYNVK
                     TRGDDALREYSAKFDKTEVTALRVTPEEIAAAGARLSDELKQAMAAAVKNIETFHSAQ
                     TLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCQKVVLC
                     SPPPIADEILYAAQLCGVQEIFNVGGAQAIAALAFGSESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDAD
                     IARKVAEAVERQLAELPRAGTARQALSASRLIVTKDLAQCVAISNQYGPEHLIIQTRN
                     ARDLVDAITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKAGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA"
     gene            complement(11653..12552)
                     /gene="hisG"
                     /locus_tag="OPY25_002834"
     CDS             complement(11653..12552)
                     /gene="hisG"
                     /locus_tag="OPY25_002834"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HCS0928407.1"
                     /translation="MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYLTLRRLDFG
                     GCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     misc_feature    complement(12600..12723)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            complement(12699..12740)
                     /gene="hisL"
                     /locus_tag="OPY25_002835"
     CDS             complement(12699..12740)
                     /gene="hisL"
                     /locus_tag="OPY25_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HCS0928408.1"
                     /translation="MTRVQFKHHHHPD"
     gene            12903..13727
                     /locus_tag="OPY25_002836"
     CDS             12903..13727
                     /locus_tag="OPY25_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCS0928409.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLAARGWQVTGSKTTLDGVEAARMSG
                     IESYPLRLEPELVCEADDLDALLDVDALVITLPARRSGPGEDFYLQAMQELVDSALAY
                     RIPRIIFTSSTSVYGDAQGVVKENTPRNPVTASGRTLKELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGQHGVNLVHLEDVVGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMTRLLGMAPPHFRDAPDNGKGKIIDGSRICNELGFEYQYPDPLVMPME"
     gene            13773..14687
                     /locus_tag="OPY25_002837"
     CDS             13773..14687
                     /locus_tag="OPY25_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0928410.1"
                     /translation="MKPLLDVLIILDALEKEGSFAAASAKLFKTPSALSYTVHKLEND
                     LNIQLLDRSGHRARFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIDAFYQRHSVTRLKFVNGVLGGSWETLTQGRADIIVGAMRAPPPDTGFG
                     FARLGDLELVFAVAPHHPLVHEEEPLSRQTIKRFRAIVVGDSVHSSRSIGSELLDAQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLESGALIEKKVVAQIVYEPVWVGWNEQ
                     TAGLASGWWRDEILANNAIAGVYAKSPV"
     gene            14921..14983
                     /gene="yoeI"
                     /locus_tag="OPY25_002838"
     CDS             14921..14983
                     /gene="yoeI"
                     /locus_tag="OPY25_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HCS0928411.1"
                     /translation="MGQFFAYATAFAVKENDHVA"
     gene            14973..16331
                     /gene="plaP"
                     /locus_tag="OPY25_002839"
     CDS             14973..16331
                     /gene="plaP"
                     /locus_tag="OPY25_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HCS0928412.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWVFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGLIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAGIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(16467..17897)
                     /gene="sbcB"
                     /locus_tag="OPY25_002840"
     CDS             complement(16467..17897)
                     /gene="sbcB"
                     /locus_tag="OPY25_002840"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HCS0928413.1"
                     /translation="MTVKNDSIQSTFLFHDYETFGTHPALDRPAQFAALRTDNDFNVI
                     GEPEVFYCKPADDYLPQPGAVLITGITPQEAREKGENEAAFARRIHALFTVPKTCVVG
                     YNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDD
                     GLPSFRLEHLTQANGIEHSNAHDAMADVYATIAMAQLVKTRQPRLFDYLYSHRSKHKL
                     AALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELD
                     SDTLRERLYTAKADLGDHAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDN
                     LKVLRENPQVRDKVVAIFAEAEPFATSDNVDAQLYDGFFSDADRAAMKIVLETEPRNL
                     PALDITFVDKRIEKLLFNYRARNFPGTLDDAEQQRWLEHRRQVLTPEFLQQYANELQM
                     LSQQYAEDKTKLGLLKSLWQYATEIV"
     gene            complement(18264..20302)
                     /locus_tag="OPY25_002841"
                     /pseudo
     CDS             complement(18264..20302)
                     /locus_tag="OPY25_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461011.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="type III secretion system effector HECT-type E3
                     ubiquitin transferase"
BASE COUNT         4756 a         5024 c         5378 g         5144 t
ORIGIN      
        1 atgtgtcggt tggttttgga ttcgtttgcg acattataca taccgcaagc cattttggta
       61 tgagttaaaa gaaatttttc gtacgatagt tatttttgct atatttgatt tggctctgat
      121 agcgtttaca aaatggcagt tttcacgcta tgtctgggtg ttttgttgga cttttgccat
      181 aatcctggtg cctttttttc gcgcacttac aaagcattta ttgaacaagc taggtatctg
      241 gaagaaaaaa actatcatcc tggggagcgg acagaatgct cgtggtgcat attctgcgct
      301 gcaaagtgag gagatgatgg ggtttgatgt tatcgctttt tttgatacgg atgcgtcaga
      361 tgctgaaata aatatgttgc cggtgataaa ggacactggg actatttggg atttaaatcg
      421 tacaggtgat gtccattata tccttgctta tgaatacacc gagttggaga aaacacattt
      481 ttggctacgt gaactttcaa aacatcattg tcgttctgtt agtgtagtcc cctcgtttag
      541 aggattgcca ttatataata ctgatatgtc ttttatcttt agccatgaag ttatgttatt
      601 aaggatacaa aataacttgg ctaaaaggtc gtcccgtttt ctcaaacgga catttgatat
      661 tgtttgttca ataataattc ttataattgc atcaccactt atgatttatc tgtggtataa
      721 agttactcga gatggtggtc cggctattta tggtcaccag cgagtaggtc ggcatggaaa
      781 actttttcca tgctataaat ttcgttctat ggttatgaat tctcaagagg tactaaaaga
      841 acttttggct aacgatccta ttgccagggc tgaatgggaa aaagatttta aactgaaaaa
      901 tgatcctcga atcacagctg taggtcgatt tatacgtaaa actagccttg atgagttgcc
      961 acaacttttt aatgtactaa aaggtgatat gagcctggtt ggaccacgac ctatcgtttc
     1021 ggatgaactg gagcgttatt gtgatgatgt tgattattat ttgatggcaa agccgggcat
     1081 gacaggtcta tggcaagtga gtgggcgtaa tgatgttgat tatgacactc gtgtttattt
     1141 tgattcctgg tatgttaaaa actggacgct ttggaatgat attgccattc tgtttaaaac
     1201 agcgaaagtt gttttgcggc gagatggtgc gtattaagct taccgagaag tactgaataa
     1261 taattgtata aaatagcctg cgtaaaatct gaacgcatca atcgctacct taatatcata
     1321 cctttgagtt aacatactat tcacctttaa cctgccatga ccgtttgtgg cagggtttcc
     1381 acacctgaca ggagtatgta atgtccaagc aacagatcgg cgtcgtcggt atggcagtga
     1441 tggggcgcaa cctcgcgctc aacatcgaaa gccgtggtta taccgtctcc gttttcaacc
     1501 gctcccgtga aaagaccgaa gaagtgattg ccgagaatcc cggcaaaaag ctggtgcctt
     1561 attacacggt gaaagagttt gttgaatccc tcgaaacgcc tcgtcgtatc ctgttaatgg
     1621 tgaaagcggg tgcaggtact gatgcagcta tcgattcgct gaaaccgtat ctggaaaaag
     1681 gcgatatcat tattgatggc ggtaacacct tcttccagga cacaatccgt cgcaatcgcg
     1741 agctgtctgc ggaaggtttt aactttatcg gtaccggtgt ttccggtggt gaagagggcg
     1801 cgctgaaagg gccatctatc atgcctggcg gtcagaaaga tgcctatgaa ctggtggcgc
     1861 cgatcctgac gaagattgct gctgtggcag aagatggcga accgtgcgtg acctatatcg
     1921 gcgccgatgg cgcgggtcac tacgttaaga tggtccacaa tggtattgaa tatggcgata
     1981 tgcagcttat cgctgaagct tactccttgc tgaaaggcgg cctgaatctc agcaatgaag
     2041 agttggcgaa cacttttact gagtggaata acggcgagct gagcagttat ctgatcgaca
     2101 tcactaaaga catcttcact aaaaaagatg aagacggtaa ttacttgata gatgttattc
     2161 ttgatgaagc cgccaacaaa gggaccggta aatggaccag ccagagcgcg ctggatctgg
     2221 gcgaaccgct gtcgctgatt accgaatccg tctttgcgcg ttacatctct tcgctgaaag
     2281 cgcaacgtgt tgccgcatct aaagtgctct ccgggccgaa agcgcagccg gcgggcgaca
     2341 aagcggaatt tatcgagaaa gtgcgtcgcg cgctgtatct tggcaagatc gtctcctatg
     2401 cgcagggctt ctcgcagcta cgcgccgcgt ctgatgaata tcactgggag cttaactacg
     2461 gcgagattgc taagattttc cgtgcgggct gtatcattcg cgctcagttc ctgcagaaga
     2521 tcaccgatgc ttacgcagaa aacgccggta tcgctaactt gctgttagcg ccttacttca
     2581 agaaaattgc tgatgagtac cagcaggcgc tgcgtgatgt tgtggcttac gcggtgcaga
     2641 atggcattcc ggtgccgaca ttctctgcgg cagtggccta ctatgacagc tatcgcgccg
     2701 cagtactgcc agctaactta attcaggcgc agcgtgacta ctttggtgcg cacacctata
     2761 aacgtactga taaagaaggc attttccata ccgagtggtt ggaataattt ctgcaagctt
     2821 gtttaagccc ggtttaatac tgggcttttt tttatctcta ttcttattga tttatcgctt
     2881 ttgcttaata ttaacttaat aatctgtgtt tatcgtaatg aagataatct gaattgtttt
     2941 cgtctgcgtt gcactttata tactcaggcg ttaaaacttt gatatcttat caggatgcga
     3001 aatacatcat gattcataat taagttaatt ctgagagcga ataatgaaaa tcacgatatc
     3061 cgggacgggt tatgttggct tgtctaatgg tttgcttatt gcacaacacc atgatgtggt
     3121 ggcgttagac attgttcctg cccgtgttga actgttaaat gatcggatat ctccgattgt
     3181 tgataaagaa attcagcaat ttttaaagga agataacatc agattcaggg caacgctgga
     3241 taagtttgat gcataccaga atgcagatta cgtcatcatt gctacgccta cagattacga
     3301 tccaaaaacc aactatttta atacgttcag tgtagaatcg gtcattcagg atgtgatcag
     3361 catcaacccc gcagccgtga tgattattaa gtctacggtg ccggttggct ttacggcggc
     3421 aatgcgtcag aagtttgcga cagaaaatat cattttctct ccggaatttt tacgtgaagg
     3481 taaagccctt tacgataacc tttatccctc ccgtatcgtg attggggaac agtctgagcg
     3541 cgcccgagaa tttgccgcat tactccagga aggcgctatt aaacaggaga ttccgacgct
     3601 gtttacggac tccactgaag cggaagccat taaacttttc gccaatactt acctcgccat
     3661 gcgagtcgct tattttaatg aattagacag ttatgctgaa acgttaggat taaatacccg
     3721 acaaattatt gaaggggtgt gcctcgaccc gcgtattggc aatcattaca ataatccctc
     3781 ttttggttat ggcggatatt gtttgccaaa agataccaaa cagttgctgg ctaattatca
     3841 gtcagtgcct aataatatta tctccgctat cgttgaagca aaccgtacgc gtaaagattt
     3901 tattgccgat tctatccttg ccagaaagcc taaagtggtg ggcatttatc gcctgattat
     3961 gaagagtggc tccgataact tccgcgcctc atcgattcag gggattatga aacgtattaa
     4021 agcgaaaggc gtagaggtca tcatctatga gccggtaatg caagaagaaa ctttctttaa
     4081 ctcacgtctt gaacgtgatt tgcactgctt taaacagcag gcggatgtca ttatttccaa
     4141 tcggatggcg gcagagcttt tggatgtcgc tgaaaaagtg tatacccgcg atcttttcgg
     4201 tagtgattaa taaggcaatc ggggctgatg agtcccgatg atttattgac caaatggaaa
     4261 taatgtctga tttttatcat taatcctatg gcatatattt tctttatgac tacactgtct
     4321 ccagcttcat ctttttttag ttagggtatc tatgacagtg gatagtaatg cgtcttccgg
     4381 gcgtgggaac gatccggaac agattgattt gattgagtta ttgctacagt tatggcgtgg
     4441 gaagatgacc attattgtag ccgttattat cgccattttg ctggccgtag gctacctgat
     4501 gatagccaaa gaaaaatgga catccacggc gattattacc caacctgatg ccgcgcaggt
     4561 tgccacctat accaacgcgc tcaacgtctt gtatggcggg aatgccccca aaatctctga
     4621 agtgcaggcg aattttataa gccgctttag ttctgcgttt tccgcattat cggaagcgct
     4681 ggataatcag aaagagcggg aaaagctcac cattgaacag tcggtaaagg ggcagacgct
     4741 gccgctctcg gtttcttatg tgagcactac cgctgaaggg gcgcagcgtc ggctggcgga
     4801 atatatccaa caggtggatg aagaggtcgc taaggaactg gaagttgacc tgaaagataa
     4861 catcacgctg caaaccaaaa cgttgcagga gtcccttgag acgcaggaag ttgtggcgca
     4921 ggagcaaaaa gatctgcgta ttaagcaaat cgaagaagcg ttgcgctatg cggatgaggc
     4981 caaaatcacg cagccgcaga ttcagcaaac ccaggatgtt acccaggaca cgatgttcct
     5041 gttggggagc gatgcgctaa aatcgatgat acagaacgaa gcgacgcgtc cactggtctt
     5101 ttctccggcc tattaccaga cgaagcagac actgctggac attaaaaatc tgaaagtgac
     5161 tgccgatacg gtgcacgtct atcgttatgt gatgaagccg acgctgccgg tccgtcgcga
     5221 tagcccgaaa acagccatta ccctcgtgct ggctgtgttg ctgggcggga tgatcggcgc
     5281 cgggattgtg ctggggcgca atgcgctacg tagctataag ccaaaagcct tgtaagcttc
     5341 tttgccggat ggtggtcggc ttcgaaaggt aaaatttctc attaaaaaac cgggcattgc
     5401 ccggtttttt tacgcttatt gatgacgctt acgaagatcg tcgatcacgg tggtgaggtt
     5461 gagatcctga tcctgcaaca gcaccagcag gtggtacatc aaatcagacg cttcattggt
     5521 taattcaaaa cgatcattga cggtggccgc cagcgcggtt tctacacctt cttcgccaac
     5581 tttttgcgca atacgtttgg taccgctggc gtacagtttc gccgtgtaag agctggccgg
     5641 atcggcggtt ttgcgctctg ccagtagctg ctccagttga tacaggaata accactgatg
     5701 gctggcgtcg ccaaagcagc tgctggtacc tttgtggcag gtcggcccga cagggtttgc
     5761 cagcaccagc agtgtatcgt tgtcgcaatc tggcgcaatg ctgacgacat tcagcacatg
     5821 gcctgaggtt tcgcctttgg tccataaacg ctgtttcgtg cgtgagaaga acgtgacatg
     5881 gccggattca atggttttgt ccagcgcttg tgggttcata tagcccagcg tcaatacttc
     5941 gccggatacc gcatgttgca cgatggctgg catcaggcca tcggtttttt cccagtccag
     6001 ctcgcggcgt tgttgctctg ttaacatatc ctgatctcca cgccctggcc tgccaggtac
     6061 gcttttaatt cgccaatatt gatgatttgc ttgtgaaaaa cggaggcggc aagcgcgccg
     6121 tcgacatcgg catcacggaa tgcctcaaga aagtgttcca tcgtgcccgc gccgccggag
     6181 gcgatcagcg gcacgcggca aacgtcacgg acttttttca actgcgtcag atcataaccg
     6241 ttacgcacgc cgtcctggtt catcatattc aggacgattt cccccgcgcc gcgctgttgt
     6301 acctcttgca cccagtccag cgtctcccac tgcgtcacgc gggtacggtt ttcatcgccg
     6361 gtatactggt taacatgata tttccccgtg gcgtcgtcaa accaggtatc aatcccgacg
     6421 acaatgcact gcacgccaaa acggtcagcc agacgggtaa tcagcgttgg gtcagccagt
     6481 gcaggggagt tgatagagat cttatccgcc ccgaaagaga gaattttggc ggcgtcgtca
     6541 attgaccgga taccgcccgc tacacaaaac ggaatgtcga tcacctcggc aacgcgcgct
     6601 acccagcttt tatcgactac gcgaccatcg ctggaggcgg taatgtcata gaacaccagt
     6661 tcgtccgcgc cttcgtcggc atagcgtttg gccagcggaa cgatatcgcc aatgatctca
     6721 tggttgcgaa actgtacgcc ttttaccacc tgaccatcac gaacgtccag acacggaatt
     6781 atacgttttg ccagcattgg atggcctcct taacggtaaa tttcccttcc aacagcgcgc
     6841 gtccgacaat cacgccgcgc acgccggtgc cgcgcagggc ggcaatatca tcgatatcgc
     6901 caataccgcc ggaggattga aaggcgatct gcggatatct ggcgcatatc tcttcgtaca
     6961 gtgaaacgtt agagcccgcc agcgtgccgt cgcgagaaat atcggtacac agtacatgtt
     7021 tcaggccgac ggggagatag gtctccacca gttgttccag cgagacgccg gaattttcct
     7081 gccagccgct aaccgccacc tgcttgttgc cgtgttcgtc tatgcgaacg tccagcgcca
     7141 gtaccagcgc ctgcgcgcca aaacgttcaa accagccttt caccacgtca ggggatttca
     7201 ccgccgttga accgatgacc acacgggcaa cgccagcttt cagtaatgcc gcaacgtctt
     7261 cttcggtacg cacgccgccg ccgacctgaa caggcacgtt cacgcccgcg accagagttt
     7321 taatcagcgg tatctgtcgc ttagccggat ctttagcgcc ggtcagatct accagatgta
     7381 gcaccccggc gccctgggcg gcgtaatcct gcaaacgggg caggggatcg ttaccgtaat
     7441 cccgctgccg ggcgtagtcg ccctggtgga gacgcaccac ggtgccgtca attaaatcta
     7501 atgccggaat aatcattaca tctccaggaa gtttttcagc aactgtgcac ccgccgcgcc
     7561 cgaacgttcc ggatggaact gtacgccgaa gaaattatct ttctgtaccg ccgcggtaaa
     7621 cggctcgccg taattgcact gggcgatagt ccacgggttg accggcatcg cgtagctgtg
     7681 aacaaagtaa aaataggcgc catcttcaat gccctgaaac agccggttgc ccgcctgcgg
     7741 atacacgcga ttccagccca tgtgtggcag cggcagacca aagtcggtca ttttcggcac
     7801 atcttgttcg ataatgttca gcagatccac gccgcgcgtc tcttcgctgc gacgacccag
     7861 cagttgcatc cctaagcaga tacccagtac cggctgagta cacgctttaa ttaagtcgat
     7921 cagttcacgt tcgcgcagtt gatccatagc ggcttgcgcc gtgccgacgc cgggcagaaa
     7981 gagtttgtca gcgcgtaata cgatttccgc ttcgcggctg accaccgggg tgtaaccgtg
     8041 gcgcgccacg gcggatttta ccgagcttaa attggcgcag ccggtgtcaa ggatgacgac
     8101 gttcatcaca gcactccttt cgaggacggt aatgtatcgc cctccacgcg aatagcctgg
     8161 cgtagcgtcc gaccaaaggc tttaaacaaa ctttcgacac ggtggtgatc gttcttacct
     8221 ttagtcttga gatgcagagt gacgcccatc gtgtaagaga gtgagcggaa aaagtgttca
     8281 atcatctctg tgctcaaatc gcccacacgc tggtaggtaa attcagcttt atattccaga
     8341 tgcggacgac cggaaatatc cagcgcgcag cgcgccagac attcatccat cggtagtaca
     8401 aagccaaaac ggcagatacc gcgcttgtcg ccgagtgcca gttttaacgc ctcaccgagc
     8461 gccagcccgg tatcttctac cgtgtggtga tcgtcgatat agagatcgcc cttaacggta
     8521 atctccatgc gaaagccgcc gtgggtggcg atttgatcga gcatatggtc aaagaagccg
     8581 acgccggtat taatcttgct gttgccttcg cgatccagcc agacgctgac atcaatctgt
     8641 gtctctttgg tgttgcggac cacatgcgca tagcgatcgc gtttcgttag ctgttcgcca
     8701 atcatcgtcc agttcaacgt ttcacggtga tagcgtaaac cagtaatgcc catattatca
     8761 gcgagttgga tatcggttgc acgatcgcca atcacatagc tgttggcgct atccatcgct
     8821 tgttccgcaa gataacgctc caccagcttc actttgggct tgcggcagtc gcagtcgtct
     8881 gcgggcaggt gagggcagat cagcacctca tcaaagcata cgccctgaga agtgaaaatc
     8941 tgcatcatca ggttgtgcgg tccgtcgaag tccgcctgcg ggaagctttg cgtgccaagt
     9001 ccatcctggt tagtgatcat caccagctta aaaccggctt tttgcagctt cagcaatacg
     9061 ggaatcacct ctggctcaaa ggccagttta tcaaagtggt ctacctgaaa atcgctcggc
     9121 ggttcggaaa ttaaggttcc gtcccggtcg atgaaaagat acttctgact catactggct
     9181 ccgcacgtaa ggcgtcaatg acgcgctggt tttcctggcg ggtgccgacc gtaatccgca
     9241 ggcagccgct taaagaaggt tgtttattct gatcgcgtaa gataatgccc tgatcccata
     9301 aggatttaaa cacgctgctg gaggcggtaa accgcgccag aatatagttg gtttcagagt
     9361 caaagacgtg ttctacgcag gcggtctgtt gcagggcatt caccagatac tgacgttcct
     9421 gcactgtctg cgccacgcga tcgcgcatta cgtttattcc ctgcgggctc agcgcttggg
     9481 cggcgatatc cgccactggc gtagaaagcg gataaggggc gatcactttt aacagcaggt
     9541 tgatcacctc ttcattagcc agcgtaaagc cgcagcgcag acccgccagc gcaaaagctt
     9601 tcgacaatgt gcgcaggata accagatgag gatatttaac cagccagcct gccagcgtgg
     9661 cctgcgggca aaactcaata taagcttcgt cggcgacgac tatcgcttta ccgcgtgtca
     9721 actccagcag cgtgcgcaga tcctgcgggt tgataagttg cccggtagga ttattggggc
     9781 tacaaacgaa caccactttt gcgccgtcaa ggttgtcgga aatcccctgt agatccagct
     9841 gccagttttc aagcgcggga accgtccggc gctctacgcc aatggtttcg gcgctgacgc
     9901 tgtacatacc gtaagtgggc ggacagtaga gaatggcgtc tttccccggt tcgcagaagg
     9961 cgcggatcac cagttcgatc ccttcatccg cgccgcggct gaccagcacc tgctccggct
    10021 ttacgccagc atattgcgcg tagttttcaa tcacggcctt tggctggcat tccgggtagc
    10081 ggttaagcgt ttgttgggtg agctgaaact ccaccgctgt cgggaattca ttcgcgttca
    10141 gccagacatc gccgttaccg cccagacggc gggcggactg atacggtacc aggttgcgga
    10201 cattttcacg ggctaagtct gcgacgctga gagtgttttc agtgctcatg cttgctcctt
    10261 gagggcgttt acgcgcaggg tcacggcatt tttatgggcg gtcagacgtt ctgccgccgc
    10321 caatgtttca atggttgatg ccagagcgga aaagcccgct ttcgacagtt cctgaacggt
    10381 catccgtttc tggaaatccg ctaacccaag gctggaacag gtagcagtat agccataggt
    10441 cggtaaaaca tggttggttc cggaagcgta atcaccggcg gattccggcg accagtcgcc
    10501 gagaaatacc gagcctgcgc tggtaatcgc atccaccaaa tcgcgcgcat tgcgcgtctg
    10561 gataattaag tgttccggcc catactgatt agagatggcg acgcactgcg ctaaatcttt
    10621 ggtcacaatc agacgactgg cgctcagggc ctgccgggcg gtgcccgcgc gcggcagttc
    10681 cgccagttga cgttctaccg cctccgccac cttgcgggca atgtcagcat ccggcgtcag
    10741 caggatcacc tgggaatccg ggccgtgctc agcctgggag agcaggtcag aagcgacgaa
    10801 atccggtgtt gcgccgctgt cggcgatcac cagcacttca gacggcccgg ctggcatatc
    10861 gatagccgcg ccgtcgagac gctggctgac ctgacgcttg gcttcggtta caaaggcgtt
    10921 gccggggcca aaaattttat ccactttcgg tacggactcg ctgccgaagg ccagagcggc
    10981 aatcgcctgc gcgccgccga cgttaaagat ttcctgcacg ccacacagtt gcgccgcata
    11041 gaggatttca tcagcgatgg gtggcggcga gcacagaacc accttctggc atcccgcaat
    11101 gcgcgccggc gtcgccagca tcagcaccgt tgagaagagc ggagccgagc cgccgggaat
    11161 atacagaccg acagacgcga cgggacgcgt aacctgctgg caacgcacgc ctggctgggt
    11221 ttccacatct acaggcggta gcgtctgcgc ggaatggaac gtttcaatat ttttgacggc
    11281 agcggccatc gcctgtttta attcgtcgct cagacgcgcg ccggcggcgg cgatctcttc
    11341 aggggtgacg cgtagcgctg tcacttctgt tttatcaaat ttagcgctgt attcacgcag
    11401 ggcatcgtca ccgcgcgttt ttacattata cagaatatcg ctgaccgtcc gggtaatact
    11461 gtcagaggcg gaaatcgccg gacgcgtcag cagcgcacgc tgctgttcag ggctacagct
    11521 gttccagtca atcagggtat tgaagctcat ggtctttact ccatcacagg gttccgcctt
    11581 atccggccta ctgaacccaa aatatcaacg cattacgtag gcctgataag cgcagcgcca
    11641 tcaggcgtca gatcactcca tcatcttctc gatcggcagt accagaatcg agctggcgcc
    11701 aagcgctttc agtttctcca tggtttccca gaacaacgtt tcgctgctga ccatgtgcat
    11761 cgccacgcgc tgttgctcgc ctgccagcgg cagaattgtc ggcctttcgg cgcctggcag
    11821 cagggcgata acctcttcca gtcgttcact tggcgcgtgc atcatgatgt atttcgattc
    11881 gcgcgcctga atcacgccct gaatacgggt cagcaattta tcgatcagct gttgcttgct
    11941 ctgtgccatc tcaccgtcgc gctgaatcag acaggcttta gagcggtaga taacttcgac
    12001 ttcacgcagg ccgttagctt caagcgtcgc gccggtagag accaaatcgc agatagcgtc
    12061 ggccagcccc gcgcgcggcg cgacttcgac agaaccattt aacagacacg atttaaaaga
    12121 gacgcctttc tggtcgaggt agcgtttgag gaggtgcgga taagaggtag cgatacgttt
    12181 accgtccagc gcggccgggc cgtcccaggc ttcgtcaacc ggcgttgcca gcgataaacg
    12241 gcagccgccg aagtcaagac ggcgcagggt taaatagcgt ggatcttcgc cctgcgcgcg
    12301 gcggttgagt agctcttctt ccagcacgtt ttcgccgata ataccgagat cgaccacgcc
    12361 atccatcacc agacccggaa tgtcatcatc acgcacgcgc aggatatcaa tcggcatgtt
    12421 ttccgccatc gcaatcaggc gctgagtgtg taaattaatt tttatgccgc agcgggccag
    12481 caattctcgt gaatcatcgc ttaaacggcc tgatttctga atagctatgc gtaagcgggt
    12541 gttgtctaac attctgcgtt cctctttatc ctgtctgaac cggtctgtat cgcgcgccaa
    12601 aaaaaaagcc cccggaagat gatcttccgg gggctttctc atgcgttcat gcaccactgg
    12661 aagatctgaa tgtcttccag cacacatcgc ctgaaagact agtcaggatg atggtgatgt
    12721 ttaaattgaa cgcgtgtcat aaaaattccg atgaatgctt attcatttga taccttttaa
    12781 cctaaaccac ttttacgcct taaagcaagc gcttttttca tttcgcattt atagtatgaa
    12841 ttgtcagtca cggcgggctg gcgtagcctt atgtataagg cgttaaagtc aggagaaaat
    12901 ggatgaaaaa ggtcgcaatt gtcggtttag gttggttagg catgccgctg gcaatgtcgc
    12961 tggcagcgag aggctggcag gttaccggca gcaaaaccac ccttgacggg gtggaagcgg
    13021 cccgtatgag tggaattgaa agctatccgc tgcgtctgga gccggagctg gtctgtgagg
    13081 cggacgatct tgacgctctg ctggatgtcg atgcgctggt gataacactg cccgcgcgcc
    13141 gtagcggtcc gggagaggat ttttatctgc aggcgatgca ggagctggtc gacagtgcgc
    13201 tggcttatcg tatcccgcgt attattttta ccagttcgac gtctgtttac ggcgatgcgc
    13261 aaggcgtggt gaaagagaat acgccgcgta atccggtcac ggccagcggg cgtaccctga
    13321 aggaactgga agattggctg cataatctgc cgggcacgtc agtggatatt ctgcggctgg
    13381 cggggttagt cgggcctggg cgccatcccg gacgtttctt tgccggaaaa accgcgccgg
    13441 atggtcaaca cggggtcaat ctggtgcatc ttgaagacgt ggttggcgca attacccttt
    13501 tgctacaggc gccaaaaggg gggcacatct ataatatatg tgcgccggcg catccagccc
    13561 gcaacgtgtt ttatccgcaa atgacgcgct tgctgggaat ggcgccgccg cattttcgtg
    13621 acgcaccgga caacggcaaa gggaagatta tcgacggtag ccggatttgt aatgagctgg
    13681 gatttgaata tcaatatccc gatccgttgg tgatgccgat ggagtgagtc gctgtccagc
    13741 aggtggtcgc catatagcgc aaggggacga gtatgaaacc actgctggac gttctgatta
    13801 ttcttgatgc gttagaaaaa gaaggcagct tcgcggcggc gtcggcaaaa ttatttaaaa
    13861 cgccgtccgc cctcagttat accgttcata agctggaaaa cgatcttaat atccaactgc
    13921 tcgaccgtag cgggcatcgc gcgcgattta cgcgaaccgg taagatgcta ctggaaaaag
    13981 gccgtgaagt gttgcacacc gttcgcgagc tggaaaagca ggcgattaaa ctgcatgaag
    14041 gctgggagaa cgaactggtc atcggtgtgg atgatacctt tcccttttct cttctggccc
    14101 cgcttatcga cgctttttat caacgccaca gcgtgacgcg ccttaaattt gtcaatggcg
    14161 ttctcggcgg ttcatgggag acgctgacgc agggaagggc ggatattatt gttggcgcca
    14221 tgcgcgcgcc gccgcctgac accggctttg gctttgcaag actgggcgat cttgaactgg
    14281 tgtttgctgt cgccccgcat catccgctgg ttcatgaaga ggaaccgctt agccgccaga
    14341 cgatcaaacg ttttcgcgcg attgtggttg gcgatagcgt ccattcctcg cgatcaatag
    14401 ggtctgaact gctcgacgct caggaagcga ttaccgtgtt tgattttaaa accaagctgg
    14461 agctgcaaat tagcggcctg ggatgcggct atttaccgcg ttatctggcg cagcgatttt
    14521 tggaaagcgg cgcgcttata gagaagaaag ttgtggcgca aatcgtctat gaaccggtgt
    14581 gggttggctg gaatgaacag accgccgggc tggccagcgg ctggtggcgg gatgaaattt
    14641 tagcaaataa tgctattgct ggggtgtatg caaaatcgcc ggtttaaaaa tcaatcgctt
    14701 atgaaaaata attttttgaa cgcgctcgca ttctcttgtc atttcacttc aatttagggc
    14761 agaatatgcc gcttgcaaaa aatgacacta accgacgttt taatacgcgt cggttatttt
    14821 tttgcttcaa acacatcatt caataccaag aggccgggct tcgtaccgga tagatactta
    14881 cttaaaaatc gacagttgtt gtcgctgagg aatccagaaa atggggcaat tttttgctta
    14941 cgcgacggca ttcgccgtaa aggagaatga ccatgtcgca taacgttact ccaaacacct
    15001 ctcgcgtgga attacgtaaa acgcttacgt tagttccggt tgtaatgatg ggtcttgcct
    15061 atatgcagcc gatgacgctg ttcgatacat ttggtatcgt ttcaggcctc actgacggtc
    15121 acgtaccgac ggcgtatgca ttcgcgttaa tcgcgattct gtttacggcg ttgagctacg
    15181 ggaaactggt gcgtcgctat ccttccgcgg gttcggcgta cacctatgcc cagaaatcca
    15241 tcagcccgac cgttggcttt atggtgggtt ggtcttctct gctcgattat ctgttcgcgc
    15301 cgatgatcaa cattctgttg gcgaaaattt attttgaagc gctggtgccc tccattccct
    15361 catgggtgtt cgtcgtggcg ctggtggcct ttatgacggc ctttaacctg cgcagcctca
    15421 aatcggtcgc taacttcaac actgtgattg tggtgctaca ggtggtgctg attgcggtca
    15481 ttctgggcat ggtggtttat ggcgtatttg aaggcgaagg cgccggtacg ctggcgagca
    15541 cccgtccgtt ctggtccggc gatgcgcacg ttatcccgat gattacggga gcgacgatcc
    15601 tgtgcttctc ctttaccggc tttgacggca tcagtaacct gtcggaagag accaaagatg
    15661 ctgagcgcgt gatcccgcgt gcgattttcc tgaccgcgct gattggcggc ctaatcttca
    15721 tctttgcaac ctatttcctg caattgtact tcccggatat ctctcgcttt aaagatccgg
    15781 atgcgtctca gccggaaatc atgctgtacg tggcgggtaa aaccttccag gtgggcgcgc
    15841 tgatcttctc tactatcacc gtactggctt ccggtatggc ggcgcatgca ggcgtagcgc
    15901 gcctgatgta cgtaatgggg cgcgacggcg tattcccgaa aagcttcttc ggttacgttc
    15961 atccgaaatg gcgtacgcca gcgatgaaca tcatcctggt cggggcgatc gcgctgctgg
    16021 cgattaattt tgacctggtg atggcgacgg cgctgattaa ctttggcgcg ctggtcgcgt
    16081 ttaccttcgt taacctgtcg gtgatttcgc agttctggat ccgtgagaag cgtaataaga
    16141 cgttgaagga tcacttccag tatctgttcc tgcccatgtg cggcgcgctc acggttggcg
    16201 cgttgtgggt taacctggaa gaaagctcaa tggtactggg cctgatctgg gcgggtatcg
    16261 ggctgattta tctggcgtgc gtaactaaaa gcttccgcaa cccggttcca cagtacgaag
    16321 acgtcgcgta atcgcgcgta ttatcggcaa tagtaaaacc ggaggcagtg cctccggttt
    16381 tttgtctgcc atccagcacg tttaccggat ggcggcgtca ctatttatcc gctctggatt
    16441 aacaatgccc gtcaggcatt ggtcaattac acaatctcag ttgcgtactg ccacagtgat
    16501 ttcagcagcc ccagcttcgt tttatcttcc gcatactgct gagaaagcat ctgcaattca
    16561 ttggcatact gttgtaaaaa ctctggcgtc agtacctgac ggcgatgctc cagccagcgc
    16621 tgctgctctg cgtcatccag cgtaccggga aaattgcgtg cgcggtaatt aaacagcagc
    16681 ttctcaatgc gcttatcgac aaaggtaatg tccagcgcgg gcaggttacg cggctcggtt
    16741 tcgagtacga ttttcatggc tgcgcgatcg gcatcgctga aaaaaccatc atagagctgg
    16801 gcatcaacgt tatccgaggt ggcaaaaggt tcggcttcgg cgaaaatcgc caccactttg
    16861 tcgcggacct gcgggttttc acgcagcact ttcaggttat ccaggcaatg ctggcggtta
    16921 attcccagcc ggtcggcatc ctccgggcgc aaggtattcg cctgcgccag taccggacat
    16981 ttattgatat gcaccagctt taccggcact gcggcgtgat cgccaagatc ggctttggcc
    17041 gtataaagcc gctcgcgaag ggtgtcgctg tccagctcaa gaagaggaga aatatcgcct
    17101 gctaaatcga ccatgatcac cgcgttacgg ttttcaggat gccacgccag cggcgcgacc
    17161 cagcttgtat taccgcgcca cgcgccaaac atgccggaga catgcaccag cggcttcatt
    17221 tgcggaacgt caatcagcgc cgccagttta tgtttactgc ggtggctata aagataatca
    17281 aacagtcgcg gctggcgtgt tttcaccagt tgcgccatcg caatagtggc gtagacatcc
    17341 gccatcgcat catgcgcgtt gctgtgttcg atcccgttcg cctgggttaa atgttccaga
    17401 cgaaagctgg gcaggccgtc gtcgttttcc ggccagttaa ttccctccgg gcgcagcgca
    17461 taacaggcgc gcatgacatc caatagatcc caacgtgaat tatcatgctg ccagctccag
    17521 gcgtagggat cgtaaaagtt gcgataaaaa atattgcgcg tgacttcatc atcaaaacgt
    17581 acattgttgt agcccacaac gcaggtttta ggaacggtaa acagcgcatg aatgcgtctg
    17641 gcgaaagcgg cttcgttttc tcctttctca cgcgcttcct gcggcgtgat gccggtaatc
    17701 agcactgcgc cgggctgcgg tagataatca tcggcgggtt tgcaataaaa cacctccggc
    17761 tcgccaataa cgttgaagtc gttatccgta cggagcgcgg cgaattgcgc aggtctgtcg
    17821 agggccggat gcgtaccgaa ggtttcgtaa tcgtggaaga ggaatgtgct ctgtatgctg
    17881 tcgtttttaa ctgtcacttg atgtacacgc ctgatgttat ctgtatatga aatattttat
    17941 tcttttattt tgtcgttgat tgattgtatt tgtacaccaa ttgatattgt tgctaatgtt
    18001 cgtacatgcg atggtgagta cataaacatt aaaatcattg agtacaaaat actaaaatga
    18061 ccatcagcga cactaagcta cgctccctct atggtaaacc atattccggc ccatctgaaa
    18121 ttactgattt tgatttagta ctgtatggaa tttaggccag ggtcaatctg gccgggatct
    18181 caaaaaatgc atggactaaa acgggtctat gtacagaggg acacaacgct gtgtccctta
    18241 atttcatgcg ggttgaggct ggactaggcc caggccagtg gcaggatgga tgacagaaca
    18301 ctcgggaaat attttctggc atgacgttgc atactatcca ccacaacgct ggtacaggta
    18361 aaggcgccat ggaggccgtg aaaacggtcg gaccagtcgg taaactgttc gctggacggg
    18421 aagatcgccg gagacagctc ccagtctttc tgcatcagcg cctccgcata gcctctcagg
    18481 gccggcggag agtcatgctc agtgccgaaa atggcgctgg aggaatagcg tgcgaatgcg
    18541 gtactaagac agaacagggt ttccgcctgc ttctgtgggg tggcgtccgt caggtgataa
    18601 gcactgagga tgtgctggta gtgtgccggg ctgagtttgc cttcaggaag cagggggtca
    18661 aaaatggtgt tcagacgcga cactgaggca tcatcaatca acttcacggt ggaatgtttc
    18721 tgggtcgtgg cggcaataaa ctgctggttc agctccccgt gctcttcagc gctgaggatg
    18781 atatcaatca gttccccaaa gcgtcgctgc acggcctgct gattaaatgc ggcgagaaac
    18841 accggaaagt catgacggaa taactctacc ggagagattt gcgcggtgga aacgttctct
    18901 ccggctcgca gcaggtaaaa gttgtcccat gcagtgtcag gagtagggtt tagcattgtt
    18961 aacagcgtgt cagtggagag catcatcgcc gtgtctgaat cctgggagga aagcagcagg
    19021 aaattatctg cagcgcgggt tgtccagtcc gggctgccgt cataattgcc gaagagccca
    19081 ttatggatgt ggggagacac cgttgggtga gcaagatatc gttcataaag cgctgcagct
    19141 ttctggcggg tgccatcagt gcagcccacg cctgtcatac agtgtaaaat cacctgatta
    19201 aagagtccgt tgtgagtggt catggcggcg ttgttcctgt caaacgaatc cagcaacaca
    19261 ggccgtatgc gctgctgata atatgtgtca ggagccggca ggggaacgtc attataggtc
    19321 tggcactggt gggcaaaaaa acgttcctga acaggcccga gccactcgct gataagcgta
    19381 ctttgcgtat agggggggcc agtacgctca ccagcgaact ttcaactggc cggatacatg
    19441 cctctgttaa gcggccactc cgcaatgact taaccaggtc ttccattgcc cggacttttt
    19501 cctgactgta tttatcgggc aggctgtcaa tggttatcag aatactttta ccattattgt
    19561 gctcatgatt taaaaatcca tccacagcgt tctcagtcca aaggagtggc atttgcggcc
    19621 agatatcacc tggacgaata aaattttcgc cccctgatac tgacggaggt gatgaattat
    19681 ccggttcatt taaaataacg ccagagaggt tggctttgtg acgtataagc gtatttttta
    19741 atgttgtatc aataaaagag ggctgttgtt gtgtagtaat tgaatactgt aaaacacttc
    19801 attcatgtct gaattactaa attttgtatt actgcagact acatcactca gtgtcaaata
    19861 agtgaatcgg cattcgtcaa aatgtaaatg agatatatca gaataagtaa attttgaatt
    19921 tgaaaagttg aacctcttaa taatatcgcc gtctcgctcc atgaagctga ggggcaatat
    19981 tttgctgaat gtaatattac ggaaatctgc gtttgaaaaa tcgcgatctg cgggcgtaag
    20041 agtttctccg gctttctgcc gtaaaactgc atccgtaagt ttcttagccc agtcggcagg
    20101 tgatgacggg gaagacgtag cctgaagtga gagggagggt gatactggtg gtgttctacc
    20161 ttcagaaacc gttggcctgt tattggctga tacagagact tcaccgggga gcggggctgc
    20221 acctgtcact ctgtaattat aatcacatga ttgatttgca atatgcttac gcatgagtgc
    20281 tgcagtcatt tttgagacat ct
//
LOCUS       DAJVKX010000076        20266 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000076 DAJVKX010000000
VERSION     DAJVKX010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20266
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.076"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            4..1470
                     /gene="spiA"
                     /locus_tag="OPY25_002842"
     CDS             4..1470
                     /gene="spiA"
                     /locus_tag="OPY25_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system protein SpiA"
                     /protein_id="HCS0928414.1"
                     /translation="MLLFILNTAKSDELSWKGNDFTLYARQMPLAEVLHLLSENYDTA
                     ITISPLITATFSGKIPPGPPVDILNNLAAQYDLLTWFDGSMLYVYPASLLKHQVITFN
                     ILSTGRFIHYLRSQNILSSPGCEVKEITGTRAVEVSGVPSCLTRISQLASVLDNALIK
                     RKDSAVSVSIYTLKYATAMDTQYQYRDQSVVVPGVVSVLREMSKTSVPASSTTNGSPA
                     TQALPMFAADPRQNAVIVRDYAANMAGYRKLITELDQRQQMIEISVKIIDVNAGDINQ
                     LGIDWGTAVSLGGKKIAFNTGLNDGGASGFSTVISDTSNFMVRLNALEKSSQAYVLSQ
                     PSVVTLNNIQAVLDKNITFYTKLQGEKVAKLESITTGSLLRVTPRLLNDNGTQKIMLN
                     LNIQDGQQSDTQSETDPLPEVQNSEIASQATLLAGQSLLLGGFKQGKQIHSQNKIPLL
                     GDIPVVGHLFRNDTTQVHSVIRLFLIKASVVNNGISHG"
     gene            1451..2662
                     /gene="ssaD"
                     /locus_tag="OPY25_002843"
     CDS             1451..2662
                     /gene="ssaD"
                     /locus_tag="OPY25_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctD family type III secretion system inner
                     membrane ring subunit SsaD"
                     /protein_id="HCS0928415.1"
                     /translation="MAYLMVNPKSSWKIRFLGHVLQGREVWLNEGNLSLGEKGCDICI
                     PLAINEKIILREQADSLFVDAGKARVRVNGRRFNPNKPLPSSGVLQVAGVAIAFGKQD
                     CELADYQIPVSRSGYWWLAGVFLIFIGGMGVLLSISGQPETVNDLPLRVKFLLDKSNI
                     HYVRAQWKEDGSLQLSGYCSSSEQMQKVRATLESWGVMYRDGVICDDLLIREVQDVLI
                     KMGYPHAEVSSEGPGSVLIHDDIQMDQQWRKVQPLLADIPGLLHWQISHSHQSQGDDI
                     ISAIIENGLVGLVNVTPMRRSFVISGVLDESHQRILQETLAALKKKDPALSLIYQDIA
                     PSHDESKYLPAPVAGFVQSRHGNYLLLTNKERLRVGALLPNGGEIVHLSADVVTIKHN
                     DTLINYPLDFK"
     gene            2670..2912
                     /gene="ssaE"
                     /locus_tag="OPY25_002844"
     CDS             2670..2912
                     /gene="ssaE"
                     /locus_tag="OPY25_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YscE family type III secretion system
                     co-chaperone SsaE"
                     /protein_id="HCS0928416.1"
                     /translation="MTTLTRLEDLLLHSREEAKGIILQLRAARKQLEENNGRLQDPQQ
                     YQQNTLLLEAIEQAENIINIIYYRYHNSALVVSEQE"
     gene            3115..3441
                     /gene="sseA"
                     /locus_tag="OPY25_002845"
     CDS             3115..3441
                     /gene="sseA"
                     /locus_tag="OPY25_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system chaperone SseA"
                     /protein_id="HCS0928417.1"
                     /translation="MMIKKKAAFSEYRDLEQSYMQLNHCLKKFHQIRAKVSQQLAERA
                     ESPKKSRETESILHNLFPQGVAGVNQEAEKDLKKIVSLFKQLEVRLKQLNAQAPVEIP
                     SGKTKR"
     gene            3448..4038
                     /gene="sseB"
                     /locus_tag="OPY25_002846"
     CDS             3448..4038
                     /gene="sseB"
                     /locus_tag="OPY25_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system translocon
                     protein SseB"
                     /protein_id="HCS0928418.1"
                     /translation="MSSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYG
                     VLLILLMVIQAIANNKFIEVQKNAERARNTQEKSNEMDEVIAKAAKGDAKTKEEVPED
                     VIKYMRDNGILIDGMTIDDYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQI
                     TIQKMSQELNAVLTQLTGLISKWGEISSMIAQKTYS"
     gene            4035..4508
                     /gene="sscA"
                     /locus_tag="OPY25_002847"
     CDS             4035..4508
                     /gene="sscA"
                     /locus_tag="OPY25_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SycD/LcrH family type III secretion system
                     chaperone SscA"
                     /protein_id="HCS0928419.1"
                     /translation="MKKDPTLQQAHDTMRFFRRGGSLRMLLDDDVTQPLNTVYRYAMQ
                     LMEVKEFAGAARLFQLLTIYDAWSFDYWFRLGECCQAQKHWGEAIYAYGRAAQIKIDA
                     PQAPWAAAECYLACDNVCYAIKALKAVVRICGEVSEHQILRLRAEKMLQQLSDRS"
     gene            4511..5965
                     /gene="sseC"
                     /locus_tag="OPY25_002848"
     CDS             4511..5965
                     /gene="sseC"
                     /locus_tag="OPY25_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system translocon
                     protein SseC"
                     /protein_id="HCS0928420.1"
                     /translation="MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTF
                     GDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRPSLPDFLQTNPAVLSMMMTSLIL
                     NVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
                     ITGIFETVIGALKVVEGFLSGNPAEMASGVAYMAAGCAGMVKAGAETAMMCGADHDTC
                     QAIIDVTSKIQFGCEAVALALDVFQIGRAFMATRGLSGAAAKVLDSGFGEEMVERMVG
                     AGEAEIEALAEKFGEEVSESFSKQFEPLEREMVSPGEMEEESAEFSRNVEKNMTKNAG
                     KSFTKEGVKAMAKEAVKEALEKYAQEGEKFLLKNFRNKVLFNMFKKILYALLRDCSFK
                     GLQAIRCATEGANQMNTGMVNTEKAKLEKKIEQLITQQRFLDFIMQQTDDQKKIEQKR
                     LEGLYKGSGAALRGVLDTIDHYSSVQARIAGWRA"
     gene            5981..6568
                     /gene="sseD"
                     /locus_tag="OPY25_002849"
     CDS             5981..6568
                     /gene="sseD"
                     /locus_tag="OPY25_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system translocon
                     protein SseD"
                     /protein_id="HCS0928421.1"
                     /translation="MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMK
                     LMELAKKLRDIMRSYNVEKQRLSWELQVNVLQTQMKTIDEAFRASMITAGGAMLSGVL
                     TIGLGAVGGETGLIAGQAVGHTAGGVMGLGSGVAQRQSDQDKAIADLQQNGAQSYNKS
                     LTDIMEKATEIMQQIIGVGSSLVTVLAEILRALTR"
     gene            6571..6987
                     /gene="sseE"
                     /locus_tag="OPY25_002850"
     CDS             6571..6987
                     /gene="sseE"
                     /locus_tag="OPY25_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LcrR family type III secretion system chaperone
                     SseE"
                     /protein_id="HCS0928422.1"
                     /translation="MVQEIEQWLRRHQVFTEPAYLGETAILLGQQFILSPYLVIYRIE
                     AKEMIICEFRRLTPGQPRPQQLFHLLGLLRGIFVHHPQLTCLKMLIITDVLDEKKAML
                     RRKLLRILTVMGATFTQLDGDNWTILSAEHLIQRRF"
     gene            7039..7473
                     /gene="sscB"
                     /locus_tag="OPY25_002851"
     CDS             7039..7473
                     /gene="sscB"
                     /locus_tag="OPY25_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SycD/LcrH family type III secretion system
                     chaperone SscB"
                     /protein_id="HCS0928423.1"
                     /translation="MMMKEDQKNKIPEDILKQLLSVDPETVYASGYASWQEGDYSRAV
                     IDFSWLVMAQPWSWRAHIALAGTWMMLKEYTTAINFYGHALMLDASHPEPVYQTGVCL
                     KMMGEPGLAREAFQTAIKMSYADASWSEIRQNAQKMVDTLIA"
     gene            7489..8271
                     /gene="sseF"
                     /locus_tag="OPY25_002852"
     CDS             7489..8271
                     /gene="sseF"
                     /locus_tag="OPY25_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion systems effector SseF"
                     /protein_id="HCS0928424.1"
                     /translation="MKIHIPSAASNIVDGNSPPSGIQAKEASFPPPEIPAPGTPTVPV
                     VLTPEQIRQQRDYAIHFMQYTIRALGATVVFGLSVAAAVISGGAGLPIAILAGAALVI
                     AIGDACCAYHNYQLICQQKAPLQTASDSVALVVSALALKCGASLNCANTLANCLSLLI
                     RSGIAISMLVLPLQFPLPAAENIAASLDMGSVITSVSLTAIGAVLDYCLARPSGDDQE
                     NSVDELHADPSVLLAEQMALLCQSATTPALMDSSGHTSRGEP"
     gene            8268..8957
                     /gene="sseG"
                     /locus_tag="OPY25_002853"
     CDS             8268..8957
                     /gene="sseG"
                     /locus_tag="OPY25_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460370.1"
                     /note="SseG, from Salmonella pathogenicity island 2, is a
                     type III secretion system (T3SS) effector protein; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island 2 effector protein SseG"
                     /protein_id="HCS0928425.1"
                     /translation="MKPVSPNAQVGGQRPVNAPEESPPCPSLPHPETNMESGRIGPQQ
                     GKERLLAGLAKRVIECFPKEIFSWQTVILGGQILCCSAGIALTVLSGGGAPLVALAGI
                     GLAIAIADVACLIYHHKHHLPMAHDSIGNAVFYIANCFANQRKSMAIAKAVSLGGRLA
                     LTATVVTHSYWSGSLGLQPHLLEHLNDLTYGLMSFTRFGMDGMAMTGMQVSSPLYRLL
                     AQVTPEQRAPE"
     gene            9051..9266
                     /gene="ssaG"
                     /locus_tag="OPY25_002854"
     CDS             9051..9266
                     /gene="ssaG"
                     /locus_tag="OPY25_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle filament
                     protein SsaG"
                     /protein_id="HCS0928426.1"
                     /translation="MDIAQLVDMLSHMAHQAGQAINDKMNGNDLLNPESMIKAQFALQ
                     QYSTFINYESSLIKMIKDMLSGIIAKI"
     gene            9244..9534
                     /locus_tag="OPY25_002855"
     CDS             9244..9534
                     /locus_tag="OPY25_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscG/YscG/SsaH family type III secretion system
                     needle protein co-chaperone"
                     /protein_id="HCS0928427.1"
                     /translation="MESLLKSEVISDDVRRLLLEIMFAGVNHSLISQVHAMLPALTVI
                     VPDKKLQLVCLALLLAGLNEPLKAAKILSDIDLPEAMALRMLFPAPNEGFEN"
     gene            9546..9794
                     /gene="ssaI"
                     /locus_tag="OPY25_002856"
     CDS             9546..9794
                     /gene="ssaI"
                     /locus_tag="OPY25_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctI family type III secretion system inner rod
                     subunit SsaI"
                     /protein_id="HCS0928428.1"
                     /translation="MSIVPVSTQSYVKSFAEPSQEQINFFKQLLKDEASTSNASALLP
                     QVMLTRQMDYMQLTVGVDYLARISGAASQALNKLDSMT"
     gene            9791..10540
                     /gene="ssaJ"
                     /locus_tag="OPY25_002857"
     CDS             9791..10540
                     /gene="ssaJ"
                     /locus_tag="OPY25_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     lipoprotein SsaJ"
                     /protein_id="HCS0928429.1"
                     /translation="MKVHRIIFLTVLTFFLTACDVDLYRSLPEDEANQMLALLMQHHI
                     DAEKKQEEDGVTLRVEQSQFINAVELLRLNGYPHRQFTTADKMFPANQLVVSPQEEQQ
                     KINFLKEQRIEGMLSQMEGVINAKVTIALPTYDEGSNASPSSVAVFIKYSPQVNMEAF
                     RVKIKDLIEMSIPGLQYSKISILMQPAEFRMVPDVPARQTFWIMDVINANKGKVVKWL
                     MKYPYQLMLSLTGLLLGVGILIGYFCLRRRF"
     gene            10558..11106
                     /locus_tag="OPY25_002858"
     CDS             10558..11106
                     /locus_tag="OPY25_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0928430.1"
                     /translation="MLQLYRYFWQPARYAVPEWLDKLGFHLSNCWRYGDRPKLDRLLD
                     RALNRLRGSSVIPACLNDRQKRQIRLAPRISAFAFGLGLFKLRCSDYFMLPEYRQLLL
                     QWFSEDEIWQLYGWLGQRDGKLLPPQVMQQTALQIGTAILNREAHDDAVLHALLVLLP
                     PPQRILWPKTSLTEIIFMEHLL"
     gene            11103..11777
                     /gene="ssaK"
                     /locus_tag="OPY25_002859"
     CDS             11103..11777
                     /gene="ssaK"
                     /locus_tag="OPY25_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaK"
                     /protein_id="HCS0928431.1"
                     /translation="MSFTSLPLTEINHKLPARNIIESQWITLQLTLFAQEQQAKRVSH
                     AIVSSAYRKAEKIIRDAYRYQREQKVEQQQEIAWLRKNTLEKMEVEWLEQHVKHLQED
                     ENQFRSLVDHAAHHIKNSIEQVLLAWFDQQSVDSVMCHRLARQATAMAEEGALYLRIH
                     PEKEALMRETFGKRFTLIIEPGFSPDQAELSSTRYAVEFSLSRHFNALLKWLRNGEDK
                     RGSDEY"
     gene            11743..12759
                     /gene="ssaL"
                     /locus_tag="OPY25_002860"
     CDS             11743..12759
                     /gene="ssaL"
                     /locus_tag="OPY25_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaL"
                     /protein_id="HCS0928432.1"
                     /translation="MVKIKEVAMNIKINEIKMTPPTAFTPGLVIEEQEVISPSMLALH
                     ELQETAGAALYETMEEIGMALSGKLRESNKFTDAEKLERRQQALLRLIKQIQEDNGAA
                     LRPLTEENSDPDLQNAYQIIALAMALTAGGLSKKKKRDLQSQLDTLTAEEGWELAVFS
                     LLELGEVDTATLSSLKRFMQQAIDNDEMPLSQWFRRVADWPDRGERVRILLRAIAFEL
                     SICIEPSEQSRLAAALVRLRRLLLFLGLEKECQREEWICQLPPNTLLPLLLDIICERW
                     LFSDWLLDRLTAIVSSSKMFNRLLQQLDAQFMLIPDNCFNDEDQREQILETLREVKIN
                     QVLF"
     gene            12817..13185
                     /gene="ssaM"
                     /locus_tag="OPY25_002861"
     CDS             12817..13185
                     /gene="ssaM"
                     /locus_tag="OPY25_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaM"
                     /protein_id="HCS0928433.1"
                     /translation="MDWDLITERNIQLFIQLAGLAERPLATNMFWRQGQYETCLNYHN
                     GRIHLCQILKQTFLDEELLFKALANWKPAAFQGIPQRLFLLRDGLAMSCSPPLSSSAE
                     LWLRLHHRQIKFLESQCVHG"
     gene            13170..15215
                     /gene="ssaV"
                     /locus_tag="OPY25_002862"
     CDS             13170..15215
                     /gene="ssaV"
                     /locus_tag="OPY25_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaV"
                     /protein_id="HCS0928434.1"
                     /translation="MRSWLGEGIRAQQWLSVCAGRQDMVLATVLLIAIVMMLLPLPTW
                     MVDILITINLMFSVILLLIVIYLSDPLDLSVFPSLLLITTLYRLSLTISTSRLVLLQH
                     NAGNIVDAFGKFVVGGNLTVGLVVFTIITIVQFIVITKGIERVAEVSARFSLDGMPGK
                     QMSIDGDLRAGVIDADHARTLRQHVQQESRFLGAMDGAMKFVKGDTIAGIIVVLVNII
                     GGIIIAIVQYDMSMSEAVHTYSVLSIGDGLCGQIPSLLISLSAGIIVTRVPGEKRQNL
                     ATELSSQIARQPQSLILTAVVLMLLALIPGFPFITLAFFSALLALPIILIRRKKSVVS
                     ANGIEAPEKDSMVPGACPLILRLTPTLHSADLIRDIDAMRWFLFEDTGVPLPEVNIEV
                     LPEPTEKLTVLLYQEPVFSLSIPAQADYLLIGADASVVGDSQTLPNGMGQICWLSKDM
                     AHKAQGFGLDVFAGSQRISALLKCVLLRHMGEFIGVQETRYLMNAMEKNYSELVKELQ
                     RQLPINKIAETLQRLVSERVSIRDLRLIFGTLIDWAPREKDVLMLTEYVRIALRRHIL
                     RRLNPEGKPLPILRIGEGIENLVRESIRQTAMGTYTALSSRHKTQILQLIEQALKQSA
                     KLFIVTSVDTRRFLRKITEATLFDVPILSWQELGEESLIQVVESIDLSEEELADNEE"
     gene            15205..16506
                     /gene="ssaN"
                     /locus_tag="OPY25_002863"
     CDS             15205..16506
                     /gene="ssaN"
                     /locus_tag="OPY25_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctN family type III secretion system ATPase
                     SsaN"
                     /protein_id="HCS0928435.1"
                     /translation="MKNELMQRLRLKYPPPDGYCRWGRIQDVSATLLNAWLPGVFMGE
                     LCCIKPGEELAEVVGINGSKALLSPFTSTIGLHCGQQVMALRRRHQVPVGEALLGRVI
                     DGFGRPLDGCELPDVCWKDYDAMPPPAMVRQPITQPLMTGIRAIDSVATCGEGQRVGI
                     FSAPGVGKSTLLAMLCNAPDADCNVLVLIGERGREVREFIDFTLSEETRKRCVIVVAT
                     SDRPALERVRALFVATTIAEFFRDNGKRVVLLADSLTRYARAAREIALAAGETAVSGE
                     YPPGVFSALPRLLERTGMGEKGSITAFYTVLVEGDDMNEPLADEVRSLLDGHIVLSRR
                     LAERGHYPAIDVLATLSRVFPVVTSHEHRQLAAILRRRLALYQEVELLIRIGEYQRGV
                     DTDTDKAIDTYPDICTFLRQSKDEVCGPELLIEKLHQILTE"
     gene            16509..16886
                     /gene="ssaO"
                     /locus_tag="OPY25_002864"
     CDS             16509..16886
                     /gene="ssaO"
                     /locus_tag="OPY25_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaO"
                     /protein_id="HCS0928436.1"
                     /translation="METLLEIIARREKQLRSKLTVLDQQQQAIITEQQICQTRALAVT
                     TRLKELMGWQGTLSCHLLLDKKQQMAGLFTQAQSFLTQRQQLENQYQQLVSRRSELQK
                     NFNALMKKKEKITMVLSDAYYQS"
     gene            16867..17241
                     /gene="ssaP"
                     /locus_tag="OPY25_002865"
     CDS             16867..17241
                     /gene="ssaP"
                     /locus_tag="OPY25_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaP"
                     /protein_id="HCS0928437.1"
                     /translation="MRITKVEGSLGLPCQSYQDDNEAEAERMDFEQLMHQALPIGENN
                     PPAALNKNVVFTQRYRVSGGYLDGVECEVCESGGLIQLRINVPHHEIYRSMKALKQWL
                     ESQLLHMGYIISLEIFYVKNSE"
     gene            17222..18190
                     /gene="ssaQ"
                     /locus_tag="OPY25_002866"
     CDS             17222..18190
                     /gene="ssaQ"
                     /locus_tag="OPY25_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system cytoplasmic ring
                     protein SsaQ"
                     /protein_id="HCS0928438.1"
                     /translation="MLRIANEERPWVEILPTQGATIGELTLSMQQYPVQQGTLFTINY
                     HNELGRVWIAEQCWQRWCEGLIGTANRSAIEPELLYGIAEWGLAPLLQASDATLCQNE
                     PPTSCSNLPHQLALHIKWTVEEHEFHSIIFTWPTGFLRNIVGELSAERQQIYPAPPVV
                     VPVYLGWCQLTLIELESIEIGMGVRIHCFGDIRLGFFAIQLPGGIYARVLLTEDNTMK
                     FDELVQDIETLLASGSPMLKSDGTSSVELEQIPQQVLFEIGRASLEIGQLRQLKTGDV
                     LPVGGCFAPEVTIRVNDRIIGQGELIACGNEFMVRITRWYLCKNTA"
     gene            18258..18905
                     /gene="ssaR"
                     /locus_tag="OPY25_002867"
     CDS             18258..18905
                     /gene="ssaR"
                     /locus_tag="OPY25_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system export apparatus
                     protein SsaR"
                     /protein_id="HCS0928439.1"
                     /translation="MSLPDSPLQLIGILFLLSILPLIIVMGTSFLKLAVVFSILRNAL
                     GIQQVPPNIALYGFALVLSLFIMGPTLLAVKERWHPVQVAGAPFWTSEWDSKALAPYR
                     QFLQKNSEEKEANYFRNLIKRTWPEDIKRKIKPDSLLILIPAFTVSQLTQAFRIGLLI
                     YLPFLAIDLLISNILLAMGMMMVSPMTISLPFKLLIFLLAGGWDLTLAQLVQSFS"
     gene            18902..19168
                     /gene="ssas"
                     /locus_tag="OPY25_002868"
     CDS             18902..19168
                     /gene="ssas"
                     /locus_tag="OPY25_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaS"
                     /protein_id="HCS0928440.1"
                     /translation="MNDSELTQFITQLLWIVLFTSMPVVLVASVVGVIVSLVQALTQI
                     QDQTLQFMIKLLAIAITLMVSYPWLSGILLNYTRQIMLRIGEHG"
     gene            19169..19948
                     /gene="ssaT"
                     /locus_tag="OPY25_002869"
     CDS             19169..19948
                     /gene="ssaT"
                     /locus_tag="OPY25_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaT"
                     /protein_id="HCS0928441.1"
                     /translation="MTQQVNEWLIALAVAFIRPLSLSLLLPLLKSGSLGAALLRNGVL
                     MSLTFPILPIIYQQKIMMHIGKDYSWLGLVTGEVIIGFLIGFCAAVPFWAVDMAGFLL
                     DTLRGATMGTIFNSTMEAETSLFGLLFSQFLCVIFFISGGMEFILNILYESYQYLPPG
                     RTLLFDRQFLKYIQAEWRTLYQLCISFSLPAIICMVLADLALGLLNRSAQQLNVFFFS
                     MPLKSILVLLTLLISFPYALHHYLVESDKFYIYLKDWFPSV"
     gene            19945..>20266
                     /gene="ssaU"
                     /locus_tag="OPY25_002870"
     CDS             19945..>20266
                     /gene="ssaU"
                     /locus_tag="OPY25_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaU"
                     /protein_id="HCS0928442.1"
                     /translation="MSEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFF
                     TEKMILILIESITFTLQLVNKPFSYALTQLSHALIESLTSALLFLGAGVIVATVGSVF
                     LQVGV"
BASE COUNT         5532 a         4051 c         5051 g         5632 t
ORIGIN      
        1 ttaattttac tatttatact caatacagca aagagtgatg agttatcatg gaaaggtaat
       61 gacttcaccc tttatgccag acaaatgcca ttagcagagg ttttacatct gctctcagag
      121 aactatgata cggctattac tattagccca ttgataacag ctacatttag tggaaaaatt
      181 ccgcctggac caccggtcga tattttgaat aacctggcag cacaatatga tttgctaacc
      241 tggtttgatg gcagcatgtt atatgtatat cctgcatcgt tattaaaaca tcaggttatc
      301 actttcaata ttttatctac tggacggttc attcattact tacgcagcca gaatatcctt
      361 tcatcaccgg gatgcgaggt taaagaaatt accggtacca gagctgtgga ggtgagtggt
      421 gttcccagct gtctgactcg tattagtcaa ttagcttcag tgctggataa tgcgttaatc
      481 aaacgaaaag acagtgcggt gagtgtaagt atatacacgc ttaagtatgc cactgcgatg
      541 gatacccaat accaatatcg cgatcagtcc gtcgtggttc caggggtcgt gagtgtattg
      601 cgtgagatga gtaaaaccag cgtaccggcg tcatcgacga ccaatggttc acccgctaca
      661 caggcattgc ccatgtttgc tgccgaccca cgccagaatg cagtgatcgt tcgtgattat
      721 gcggccaata tggccgggta tcggaaactc atcacagaat tagatcaacg ccagcagatg
      781 atagagattt cggtgaaaat tatcgatgtt aatgctggag atattaacca gttaggcatc
      841 gactggggaa cggcagtgtc gctgggtggc aagaaaattg cgttcaatac aggtttgaat
      901 gacggtggtg ctagcggttt ttcaacggta atcagcgata cctcaaactt tatggtgcgt
      961 ttgaatgccc tggaaaaaag ctctcaggct tatgtacttt cccagccatc tgtggtgact
     1021 ttaaataata tccaggctgt gctggataaa aatattactt tctataccaa actgcaggga
     1081 gaaaaagtgg ctaaacttga atccatcact acgggttctt tgttgcgcgt tacacctcgc
     1141 ttgttaaatg acaatggcac gcaaaaaata atgcttaatc ttaatattca ggatggacaa
     1201 caaagtgata cgcaaagcga aacagatccg ctacccgaag tgcaaaattc tgaaattgct
     1261 tcgcaagcca cattattggc cggacaaagt ctattgctgg gagggtttaa acaaggtaaa
     1321 caaatccact cgcaaaacaa aatcccttta ttgggcgata tccctgtcgt aggtcatttg
     1381 tttcgcaatg atacgactca agtacatagt gtaatcaggc tttttttgat taaagcctca
     1441 gtagtaaata atggcatatc tcatggttaa tccaaagagt tcctggaaaa tacgtttttt
     1501 aggtcacgtt ttacaaggcc gggaagtatg gctgaatgaa ggtaacctgt cactggggga
     1561 gaagggatgc gatatttgta ttccgctggc tataaatgaa aaaattattc tgagagaaca
     1621 ggcagatagt ttatttgttg atgccgggaa agccagagtt agagttaatg gccgcagatt
     1681 taatccaaat aagccgctac catccagtgg ggttttgcag gttgcgggag tggctatcgc
     1741 gtttggtaaa caggattgtg aacttgctga ttatcaaata cccgtttcca gatcagggta
     1801 ctggtggttg gctggcgtat tcttgatttt catcggtgga atgggtgtcc tgttaagtat
     1861 tagtggtcag cctgaaacgg taaatgactt acctttgcgg gttaagtttt tattagacaa
     1921 aagcaatatt cattatgtgc gggcgcaatg gaaagaagat ggaagcctgc agttgtccgg
     1981 ttattgctcg tcaagcgaac agatgcaaaa ggtgagagcg actctcgaat catggggggt
     2041 catgtatcgg gatggtgtaa tctgtgatga cttattgata cgagaagtgc aggatgtttt
     2101 gataaaaatg ggttacccgc atgctgaagt atccagcgaa gggccgggga gcgtgttaat
     2161 tcatgatgat atacaaatgg atcagcaatg gcgtaaggtt caaccattac ttgcagatat
     2221 tcccgggtta ttgcactggc agattagtca ttctcatcag tctcaggggg atgatattat
     2281 ttctgcgata atagagaacg gtttagtggg gcttgtcaat gttacgccaa tgcggcgctc
     2341 ttttgttatc agtggtgtac tggatgaatc tcatcaacgc attttgcaag aaacgttagc
     2401 agcattaaag aaaaaggacc ccgctctttc tttaatttat caggatattg cgccttctca
     2461 tgatgaaagc aagtatctgc ctgcgccagt ggctggcttt gtacagagtc gccatggtaa
     2521 ttacttatta ctgacgaata aagagcgttt acgtgtaggg gcattgttac ccaatggggg
     2581 agaaattgtc catctgagtg ccgatgtggt aacgattaaa cataatgata ctttgattaa
     2641 ctatccatta gattttaagt gagtggaaaa tgacaactct gacccggtta gaagatttgc
     2701 tgcttcattc gcgtgaagag gccaaaggca taattttaca attaagggct gcccggaaac
     2761 agttagaaga gaacaacggt aggttacagg atccgcagca atatcagcaa aacaccttat
     2821 tgcttgaagc gatcgagcag gccgaaaata tcatcaacat tatttattat cgttaccata
     2881 acagcgcact tgtagtgagt gagcaagagt aaagtaaaaa tatcttagag cctatcccac
     2941 caggcgttaa ttggcgcagc cagtttggac acggatagcg cgcaaaaacc ggagcgtaca
     3001 cgtagtacgt gaggattttg agcactgccc aggttcaaaa tggcaagtaa aatagcccta
     3061 atgggacagg ctcttagtta gcacgttaat tatctatcgt gtatatggag gggaatgatg
     3121 ataaagaaaa aggctgcgtt tagtgaatat cgtgatttag agcaaagtta catgcagcta
     3181 aatcactgtc ttaaaaaatt tcaccaaatc cgggctaagg tgagtcaaca gcttgctgaa
     3241 agggcagaga gccccaaaaa gagcagagag acagagagta ttcttcataa cctatttcca
     3301 caaggcgttg ccggggttaa ccaggaggcc gagaaggatt taaagaaaat agtaagtttg
     3361 tttaaacaac ttgaagtacg actgaaacaa cttaatgctc aagccccggt ggagataccg
     3421 tcaggaaaaa caaaaaggta aagcataatg tcttcaggaa acatcttatg gggaagtcaa
     3481 aaccctattg tgtttaaaaa tagcttcggc gtcagcaacg ctgataccgg gagccaggat
     3541 gacttatccc agcaaaatcc gtttgccgaa gggtatggtg ttttgcttat tctccttatg
     3601 gttattcagg ctatcgcaaa taataaattt attgaagtcc agaagaacgc tgaacgtgcc
     3661 agaaataccc aggaaaagtc aaatgagatg gatgaggtga ttgctaaagc agccaaaggg
     3721 gatgctaaaa ccaaagagga ggtgcctgag gatgtaatta aatacatgcg tgataatggt
     3781 attctcatcg atggtatgac cattgatgat tatatggcta aatatggcga tcatgggaag
     3841 ctggataaag gtggcctaca ggcgatcaaa gcggctttgg ataatgacgc caaccggaat
     3901 accgatctta tgagtcaagg gcagataaca attcaaaaaa tgtctcagga gcttaacgct
     3961 gtccttaccc aactgacggg gcttatcagt aagtgggggg aaatttccag tatgatagcg
     4021 cagaaaacgt attcatgaaa aaagacccga ccctacaaca ggcacatgac acgatgcgat
     4081 ttttccggcg tggcggctcg ctgcgtatgt tgttggatga cgatgttaca cagccgctta
     4141 atactgtgta tcgctatgcc atgcagctta tggaggtaaa agaattcgcc ggcgcagcgc
     4201 gactttttca attgctgacg atatatgatg cctggtcatt tgactactgg tttcggttag
     4261 gggaatgctg ccaggctcaa aaacattggg gggaagcgat atacgcttat ggacgcgcgg
     4321 cacaaattaa gattgatgcg ccgcaggcgc catgggccgc agcggaatgc tatctcgcgt
     4381 gtgataacgt ctgttatgca ataaaagcgt taaaagccgt ggtgcgtatt tgcggcgagg
     4441 tcagtgaaca tcaaatcctc cgactacgtg cagaaaagat gttacagcag ctttctgaca
     4501 ggagctaaaa atgaatcgaa ttcacagtaa tagcgatagc gccgcaggag taaccgcctt
     4561 aacacatcat cacttaagca atgtcagttg cgtttcctcg ggttcgctgg gaaagcgcca
     4621 gcatcgtgtg aattctactt ttggcgatgg caacgccgcg tgtctgctat ccgggaaaat
     4681 tagtcttcag gaggcaagca atgcgttgaa gcaactgctt gatgccgtac ccggaaatca
     4741 taagcgtcca tcattgcctg actttttgca gaccaatccc gcggttttat caatgatgat
     4801 gacgtcattg atactcaacg tctttggtaa taacgctcaa tcgttatgcc aacagcttga
     4861 gcgggcaact gaggtgcaaa atgcattacg taataagcag gtaaaggagt atcaggagca
     4921 gatccagaaa gcgatagagc aggaggataa agcgcgtaaa gcgggtattt ttggcgctat
     4981 ttttgactgg attaccggca tatttgaaac cgtgattggc gccttaaaag ttgtggaagg
     5041 ttttctgtcc ggtaatcccg cagaaatggc tagcggcgta gcttatatgg ccgcaggttg
     5101 tgcaggaatg gttaaagccg gagccgaaac ggcaatgatg tgcggtgctg accacgatac
     5161 ctgtcaggcg attattgacg tgacaagtaa gattcaattt ggttgtgaag ccgtcgcgct
     5221 ggcactggat gttttccaga ttggccgtgc ttttatggcg acgagaggtt tatctggcgc
     5281 agctgcaaaa gtgcttgact ccggttttgg cgaggaaatg gttgagcgta tggttggtgc
     5341 aggggaagca gaaatagagg cgttggctga aaagtttggc gaagaagtga gcgaaagttt
     5401 ttccaaacaa tttgagccgc ttgaacgtga aatggtttcg ccgggcgaga tggaagagga
     5461 gtctgccgaa ttttctcgta acgtagaaaa aaatatgaca aaaaatgcgg gaaaaagttt
     5521 tacgaaagag ggggtgaaag ccatggcaaa agaagcggta aaagaagccc tggaaaaata
     5581 tgcgcaagaa ggggaaaagt ttctgttaaa aaattttcgt aataaagttc tcttcaatat
     5641 gttcaaaaaa atcctgtatg ccttactgag ggattgttca tttaaaggct tacaggctat
     5701 cagatgtgca accgagggtg ccaatcagat gaatactggc atggttaaca cagaaaaagc
     5761 gaagcttgaa aagaaaatag agcaattaat aactcagcaa cggtttctgg atttcataat
     5821 gcaacaaacg gatgaccaaa aaaagataga acaaaaacgc ttagaggggc tttataaagg
     5881 tagcggtgcc gcgcttagag gtgtattaga taccattgat cactatagta gcgttcaggc
     5941 gagaatagct ggctggcgcg cttaatctga ggataaaaat atggaagcga gtaacgtagc
     6001 actggtatta ccagcgcctt ccttgttaac gccttcttcc actccatctc cctccgggga
     6061 gggaatgggt actgaatcaa tgcttctgtt atttgatgat atctggatga agctaatgga
     6121 gcttgccaaa aagctgcgcg atatcatgcg cagctataac gtagaaaaac aacgactgtc
     6181 ctgggaactg caagtcaatg ttttgcagac gcaaatgaaa acaattgatg aagcgtttag
     6241 agcatcaatg attactgcgg gtggcgccat gttgtcggga gtgctgacga taggattagg
     6301 ggctgtaggc ggggaaaccg gtcttatagc gggtcaagcc gtaggacaca ccgctggggg
     6361 agtcatgggc ctggggtccg gtgtagcgca acgtcaaagt gatcaagata aagcgattgc
     6421 cgacctgcaa caaaatgggg cacaatctta taataaatcc ctgacggaca ttatggagaa
     6481 agcaactgaa attatgcagc aaatcatcgg cgtggggtcg tcactggtta cggttcttgc
     6541 tgaaatactc cgggcattaa cgaggtaaat atggtgcaag aaatagagca atggttgcgt
     6601 cggcatcagg tgtttactga gcctgcatat ttaggggaga ccgccatatt acttgggcag
     6661 cagtttatat tatcgcctta cctggtgatc tatcgtattg aggcaaaaga aatgattatt
     6721 tgtgagttca ggcgcctgac gcccgggcaa cctcgaccac agcaattgtt tcacttactg
     6781 ggacttttac gcgggatatt tgtgcatcac ccgcagttaa catgtttaaa gatgttgata
     6841 atcaccgacg ttctggatga aaaaaaagct atgctacgca ggaaattatt gcgcatcctg
     6901 acagtaatgg gagcgacctt tacacagctt gatggcgata actggacaat tttatccgcc
     6961 gagcatctta tccagcgacg tttttaaatg accttcctgg cgtaaatcat tatcacgtga
     7021 aaataacaat caataggtat gatgatgaaa gaagatcaga aaaataaaat acccgaagac
     7081 attctgaaac agctattatc cgttgatccg gaaaccgttt atgccagtgg ttacgcctca
     7141 tggcaggagg gggattattc gcgcgccgta atcgatttta gctggctggt gatggcccag
     7201 ccatggagtt ggcgtgccca tattgcattg gctggcacct ggatgatgct taaagaatac
     7261 acgacggcca ttaatttcta tggacatgcc ttgatgctgg atgccagcca tccagaaccg
     7321 gtttaccaaa cgggcgtctg tctcaaaatg atgggggaac ccgggttggc gagagaggct
     7381 tttcaaaccg caatcaagat gagctatgcg gatgcctcat ggagtgagat tcgccagaat
     7441 gcgcaaaaaa tggttgatac tcttattgct taaataacag aacgaaatat gaaaattcat
     7501 attccgtcag cggcaagcaa tatagtcgat ggtaatagtc ctccttccgg tatacaagcg
     7561 aaggaggcat cgtttcctcc ccctgaaatt ccagcccctg gcacccctac agttcctgtg
     7621 gtgcttacgc ctgaacaaat aaggcagcag agggattatg ctatacattt tatgcaatac
     7681 acgattcgtg cgctgggggc gacagtcgtg tttggattat cggttgctgc agcggtaatt
     7741 tctggcggag caggattacc cattgctatt cttgcggggg cggcgctcgt gattgctatt
     7801 ggggatgctt gctgtgcgta tcataattat caattgatat gtcagcaaaa ggcgccgtta
     7861 caaaccgcca gtgatagcgt tgctcttgtg gtcagtgcgc tggccttaaa atgcggggca
     7921 agtcttaact gcgctaacac ccttgctaat tgtctttctt tattaatacg ttcaggaatc
     7981 gctatttcta tgttggtttt acccctacag tttccactgc ccgcggctga aaatatagcg
     8041 gcctctttgg acatggggag tgtaattacc tccgttagcc tgacggcgat aggtgcggta
     8101 ctggattatt gccttgcccg cccctctggc gacgatcagg aaaattctgt tgatgaactt
     8161 catgccgatc ccagtgtgtt attggcggaa caaatggcat tgctctgtca atctgctact
     8221 acacctgcat taatggacag ttctggtcat acatctcggg gagaaccatg aaacctgtta
     8281 gcccaaatgc tcaggtcgga gggcaacgtc ctgttaacgc gcctgaggaa tcacctccat
     8341 gtccctcatt gccacatccg gaaaccaata tggagagtgg tagaattgga cctcaacaag
     8401 gaaaagagcg gttattggcc ggacttgcga aacgagtgat agagtgtttt ccaaaagaaa
     8461 tttttagttg gcaaacggtc attttgggcg gacagatttt atgctgttcc gctggaatag
     8521 cattaacagt gctaagtggt ggaggcgcac cgctcgtagc cctggcagga attggccttg
     8581 ctattgccat cgcggatgtc gcctgtctta tctaccatca taaacatcat ttgcctatgg
     8641 ctcacgacag tataggcaat gccgtttttt atattgctaa ttgtttcgcc aatcaacgca
     8701 aaagtatggc gattgctaaa gccgtctccc tgggcggtag attagcctta accgcgacgg
     8761 tagtgacgca ttcatactgg agtgggagtt tgggactaca gcctcactta ttagagcatc
     8821 ttaatgatct tacctacgga ctaatgagtt ttactcgctt cggtatggat gggatggcaa
     8881 tgaccggtat gcaggtcagc agcccattat atcgtttgct ggctcaggtg acgccagaac
     8941 aacgtgcgcc ggagtaatcg ttttcaggta tataccggat gttcattgct ttctaaattt
     9001 tgctatgttg ccagtatcct tacgatgtat ttattttaag gaaaagcatt atggatattg
     9061 cacaattagt ggatatgctc tcccacatgg cgcaccaggc aggccaggcc attaatgaca
     9121 aaatgaatgg taatgatttg ctcaacccag aatcgatgat taaagcgcaa tttgccttac
     9181 agcagtattc tacatttatt aattacgaaa gttcactgat caaaatgatc aaggatatgc
     9241 ttagtggaat cattgctaaa atctgaagtt attagcgacg atgttcgacg gttgctgctg
     9301 gaaatcatgt ttgcgggcgt taaccatagc ctgatttccc aggtacatgc gatgttacca
     9361 gcgctaacgg ttattgttcc ggataaaaaa ttacagttgg tatgtttggc attattgttg
     9421 gcgggtttaa atgagccgtt aaaggccgcg aaaattttat cggatattga tttgccagag
     9481 gctatggcgc tacgaatgtt atttcctgca ccaaatgagg ggtttgaaaa ttgaatattt
     9541 ctgatatgag catagtgcct gtaagcactc aatcttatgt aaagtccttt gcagaaccga
     9601 gccaggagca aattaatttt tttaaacaat tgctgaaaga tgaagcatcc accagtaacg
     9661 ccagtgcttt attaccgcag gttatgttga ccagacaaat ggattatatg cagttaacgg
     9721 taggcgtcga ttatcttgcc agaatatcag gcgcagcatc gcaagcgctt aataagctgg
     9781 atagcatgac atgaaggttc atcgtataat atttcttact gtccttacgt tctttcttac
     9841 ggcatgtgat gtggatcttt atcgctcatt gccagaagat gaggcgaatc aaatgctggc
     9901 attacttatg cagcatcata tcgatgcgga aaaaaaacag gaagaggacg gtgttacctt
     9961 acgtgtcgag cagtcgcagt ttattaatgc ggttgagcta cttagactta acggttatcc
    10021 gcatcggcag tttacaacgg cggataagat gtttccggct aatcagttag tggtatcacc
    10081 ccaggaagaa cagcagaaga ttaatttttt aaaagaacaa agaattgaag gaatgctgag
    10141 tcagatggag ggcgtgatta atgcaaaagt gaccattgcg ctaccgactt atgatgaggg
    10201 aagtaacgct tctccgagct cagttgccgt atttataaaa tattcacctc aggtcaacat
    10261 ggaggccttt cgggtaaaaa ttaaggattt aatagagatg tcaatccctg ggttgcaata
    10321 cagtaagatt agtatcttga tgcagcctgc tgaattcaga atggtacctg acgtacccgc
    10381 gagacaaaca ttctggatta tggacgttat caacgccaat aaagggaagg tggtgaagtg
    10441 gttgatgaaa tacccttatc agttgatgtt atcgttgaca ggactgttat taggagtggg
    10501 catcctgatc ggctattttt gcctgagacg ccgtttttga gccgacctga tcccgaagtg
    10561 ttgcaacttt atcgttattt ctggcaacct gctcgttacg ctgtaccgga atggctggat
    10621 aagctgggct ttcatctttc aaactgctgg cgttatggcg atcggcccaa attggatcgt
    10681 cttcttgaca gagcgttaaa tagactaagg ggaagctctg ttattccagc ctgtttaaat
    10741 gacaggcaaa aacgacagat tcgtcttgcg ccgcgtatat cggcatttgc ctttggactg
    10801 ggattattca aactcaggtg tagtgactat tttatgctac cagagtatcg gcaattgctt
    10861 ctacagtggt ttagcgagga tgagatctgg cagctatatg gttggttggg gcaaagagat
    10921 ggcaaattac ttcctccgca agtgatgcaa caaactgcat tgcagatcgg taccgccatt
    10981 cttaatcggg aagcgcatga cgatgcggtt ttacatgcgc tattagtatt attaccccct
    11041 ccgcagcgta tactttggcc gaagacttct cttaccgaga ttatcttcat ggagcatttg
    11101 ctatgagttt tacttcactt cctctgacgg aaattaacca taagctaccc gctcgaaata
    11161 ttattgagtc acagtggata acattacaat taactttatt tgcacaagag caacaagcta
    11221 agagagtttc acatgctatt gtgagctccg cttaccgtaa ggctgaaaaa atcatccgag
    11281 acgcctatcg ttatcagcgt gaacagaaag ttgagcagca acaagaaata gcgtggttgc
    11341 gtaaaaatac gctggaaaaa atggaagtag aatggctgga acaacatgta aaacatttac
    11401 aagaagatga aaatcaattt cgttcattgg tcgatcacgc cgcgcatcat attaaaaata
    11461 gtatagaaca ggttctgttg gcctggttcg accaacagtc ggtagacagt gttatgtgcc
    11521 atcgtctggc acgccaggcc acggctatgg cggaagaggg agcgctttat ttgcgtattc
    11581 atcctgaaaa agaggcattg atgcgtgaaa cttttggcaa gcggtttacg ctgattatcg
    11641 agcctggttt ctctcccgat caggctgaac tttcctcaac acgatatgcc gttgagtttt
    11701 cactttctcg tcatttcaac gcgttactga aatggttacg taatggtgaa gataaaagag
    11761 gtagcgatga atattaaaat taatgagata aaaatgacgc cccctacagc atttacccct
    11821 ggcctggtta tagaggaaca agaggttatt tcgccttcaa tgttagctct ccatgagtta
    11881 caggaaacgg cgggggcagc gctctatgag acgatggaag aaataggaat ggcgctgagt
    11941 ggtaaactgc gcgaaagtaa taaattcact gatgctgaga aactggagcg caggcagcag
    12001 gctttgctgc gtttgataaa acaaatacag gaggataatg gggcagcgtt gcgtccgctt
    12061 accgaagaga atagtgatcc tgatttacag aatgcgtatc aaattatcgc tcttgcaatg
    12121 gcgcttactg ccggcgggtt gtcaaaaaag aaaaaacgcg atttgcaatc gcaactggat
    12181 acgcttacag cggaggaggg atgggaactt gccgttttta gtttactgga acttggcgaa
    12241 gtggataccg ctacgctgtc ctcgctgaag cgttttatgc aacaggcgat agacaacgat
    12301 gaaatgccct tatcgcagtg gttcagacgc gtggcagact ggccggatcg cggtgaacgg
    12361 gtccgtattt tgctaagagc aatagccttt gaacttagca tatgcatcga accctcggag
    12421 caaagtcgtt tggccgcagc attagtacgc ttgcgtcgtt tgttgttatt ccttggcctt
    12481 gaaaaagagt gccagcgtga ggagtggatt tgccagttgc cgcctaatac attactgccg
    12541 ctactactcg atatcatttg tgagcgctgg cttttcagcg attggttgct tgatagactt
    12601 accgctatag tttcttcatc gaagatgttc aatcggttac tccaacaact tgatgcgcag
    12661 tttatgctga tacccgataa ctgttttaac gacgaagatc aacgtgaaca aattctcgaa
    12721 acgcttcgtg aagtaaagat aaatcaggtt ttattctgat acctggcttt caatatttag
    12781 gtaaattggc tttctggctc atcatgaggc gtcaggatgg attgggatct cattactgaa
    12841 cgtaatattc agctttttat tcaattagca ggattagctg aacggccttt agcaaccaat
    12901 atgttctggc ggcaaggaca atatgaaacc tgtctaaact atcataatgg tcgtattcac
    12961 ttatgtcaga tactcaagca aaccttctta gacgaagaac tgctttttaa agcgttggct
    13021 aactggaaac ccgcagcgtt ccagggtatt cctcaacgat tatttttgtt gcgcgatggg
    13081 cttgcaatga gttgttctcc acctctttcc agctccgccg agctctggtt acgattacat
    13141 catcgacaaa taaaatttct ggagtcgcaa tgcgttcatg gttaggtgag ggaatcaggg
    13201 cgcaacagtg gctcagtgta tgcgcgggtc gtcaggatat ggttctggcg acggtgttat
    13261 taatcgctat cgtgatgatg ctgttacctt tgccgacctg gatggttgat atcctgatta
    13321 ctatcaacct tatgttttca gtgatcctgc ttttaattgt tatttatctt agtgaccctc
    13381 tcgatttatc ggtatttccg tctttattac ttattactac attatatcgt ttgtcactca
    13441 caatcagcac atcacggctg gtactgttac aacataatgc cggtaatatt gtggatgctt
    13501 tcggtaagtt tgtcgtagga ggaaatctca ccgttgggtt ggtcgtattt accatcatta
    13561 ctattgtgca atttattgtc attacaaaag gtatcgagag ggtggcggaa gttagcgcac
    13621 gtttctcgct tgatgggatg ccaggcaaac aaatgagtat cgatggcgat ttgcgtgccg
    13681 gagttatcga tgcagaccat gcccgtacat taagacagca cgtccagcag gaaagccgtt
    13741 ttctcggtgc gatggacggt gcaatgaaat ttgttaaagg cgatacgatt gccggtatta
    13801 ttgttgttct ggtgaacatt atcggcggta ttattatcgc tatcgtacaa tatgatatgt
    13861 cgatgagtga ggctgttcac acttatagcg tactgtcaat cggagatggt ttatgtgggc
    13921 aaattccatc gctgctgatt tcccttagcg cgggaattat tgtcacccgt gttccgggtg
    13981 agaaacgcca gaacctggcg acagagttga gttctcaaat tgccagacaa cctcagtcgc
    14041 tcatattaac cgctgtggtt ttaatgctcc tcgctttaat tcctggcttt ccttttatca
    14101 ctctcgcttt cttttcagcg ttgttagcat tgccaattat cctcattcgc cgcaaaaagt
    14161 ctgtggtttc cgcaaatggc atcgaagcgc cggaaaaaga tagtatggtt cccggcgcat
    14221 gtcctctaat cttacgtctt accccgacgt tacattctgc cgacctgatt cgtgatattg
    14281 atgccatgag atggttttta tttgaggata ccggcgtccc tctccctgag gtgaatattg
    14341 aggttttgcc tgaacccacc gaaaaattga cggtactgct atatcaggaa cccgtgttta
    14401 gtttatctat tcccgcccag gcggattatt tattgatagg cgcggacgct agtgtggtgg
    14461 gtgacagcca gacgttaccg aacggaatgg ggcagatctg ttggctttca aaagacatgg
    14521 ctcataaggc gcaaggtttt ggactggacg ttttcgcggg cagccaacgt atctctgcct
    14581 tattaaaatg tgtcctgctt cggcatatgg gagagtttat tggtgttcag gaaacgcgtt
    14641 atctaatgaa tgcgatggaa aaaaactact ctgaactggt gaaagaactt cagcgccagt
    14701 tacccattaa taaaatcgct gaaactttgc aacggcttgt atcagagcgg gtttctatta
    14761 gagatttacg tcttattttt ggcacattaa ttgactgggc gccacgcgaa aaagatgtcc
    14821 tgatgttgac agaatatgtc cgtatcgcgc ttcgccgtca tattctgcgt cgtcttaatc
    14881 cggaaggaaa accgctgccg attttgcgga tcggcgaagg tattgaaaac ctcgtgcgtg
    14941 aatccattcg ccagacggca atggggacct atactgcgct gtcgtctcgt cataagacgc
    15001 agatcctgca acttattgag caggcgctga agcagtcagc caaattattc attgtcactt
    15061 ctgtcgacac ccgccgtttc ttgcgaaaaa ttacagaagc caccttgttc gacgtaccga
    15121 ttttgtcatg gcaggaatta ggagaggaga gccttataca agtggtagaa agtattgacc
    15181 ttagcgaaga ggagttggcg gacaatgaag aatgaattga tgcaacgtct gaggctgaaa
    15241 tatccgcccc ccgatggtta ttgtcgatgg ggccgaattc aagatgtcag cgcaacgttg
    15301 ttaaatgcgt ggttgcctgg ggtatttatg ggagagttgt gctgtataaa gcctggagaa
    15361 gaacttgctg aagtcgtggg gattaatggc agcaaagctt tgctatctcc ttttacgagt
    15421 actatcgggc ttcactgcgg gcagcaagtg atggccttaa ggcgacgcca tcaggttccc
    15481 gtgggcgaag cgttattagg gcgagtcatt gatggttttg gtcgtcccct tgatggctgc
    15541 gaactgcccg acgtctgctg gaaagactat gatgcaatgc ctcctcccgc aatggttcga
    15601 cagcctatca ctcaaccatt aatgacgggg attcgcgcta ttgatagcgt tgcgacctgt
    15661 ggtgaagggc aacgagtggg tattttttct gctcctggcg tggggaaaag cacgcttctg
    15721 gcgatgctgt gtaatgcgcc agacgcagac tgcaatgttc tggtgttaat tggtgaacgt
    15781 ggacgagaag tccgcgagtt catcgatttt acactgtctg aagagacccg aaaacgttgt
    15841 gtcattgttg tcgcaacctc tgacagaccc gccttagagc gcgtgagggc gctgtttgtg
    15901 gccaccacga tagcagaatt ttttcgcgat aatggaaaac gagtcgtctt gcttgccgac
    15961 tcactgacgc gttatgccag ggccgcacgg gaaatcgctc tggccgccgg agagaccgca
    16021 gtttctggag aatatccgcc aggcgtattt agtgcattgc cacgactttt agaacgtaca
    16081 ggaatggggg aaaaaggcag tattaccgca ttttatacgg tcctggtgga aggcgatgat
    16141 atgaatgagc cgttggcgga tgaagtccgt tcactgcttg acggacatat tgtgctatcc
    16201 cggcggcttg cagagagggg gcattatcct gccattgacg tgttggcaac gctcagccgc
    16261 gtttttccag tcgttaccag ccatgagcat cgtcaactgg cggctatatt gcgacggcgc
    16321 ctggcgcttt accaggaggt tgaactgtta atacgcattg gggaatacca gcgaggagtt
    16381 gatactgata ccgataaagc cattgatacc tatccggata tttgcacatt tttgcgacaa
    16441 agtaaggatg aagtatgcgg acccgagcta ctcatagaaa aattacatca aatactcacc
    16501 gagtgatcat ggaaactttg ctggagataa tcgcgcggcg tgaaaagcaa ttacgcagca
    16561 aacttaccgt gcttgatcag cagcaacagg cgattattac tgaacagcag atttgccaga
    16621 cgcgcgcttt agcagtgact accagactga aagaattaat gggctggcaa ggtacgttat
    16681 cttgtcattt attgttggat aagaaacaac aaatggccgg actattcact caggcgcaga
    16741 gctttttgac gcaacggcag cagttagaga atcagtatca gcagcttgtc tccaggcgaa
    16801 gcgaattaca gaagaatttt aatgcgctta tgaaaaagaa agaaaaaatt actatggtat
    16861 taagcgatgc gtattaccaa agttgaggga agtcttgggt tgccatgcca gtcttatcag
    16921 gatgataacg aggcggaggc ggaacgtatg gactttgaac aactcatgca ccaggcatta
    16981 cccattggtg agaataatcc tcctgcagca ttgaataaga acgtggtttt cacgcaacgt
    17041 tatcgtgtta gtggcggtta tcttgacggt gtagagtgtg aagtctgtga gtcaggaggg
    17101 ctaatccagt taagaatcaa tgtccctcat catgaaattt accgttcgat gaaagcgcta
    17161 aagcagtggc tggagtctca gttgctgcat atggggtata taatttccct ggagatattc
    17221 tatgttaaga atagcgaatg aagagcgtcc gtgggtggag atacttccaa cacaaggcgc
    17281 taccattggt gagctgacat tgagtatgca acaatatcca gtacagcaag ggacattatt
    17341 taccataaat tatcataatg agctgggtag ggtgtggatt gcagaacaat gctggcagcg
    17401 ctggtgtgaa gggctaattg gcaccgctaa tcgatcggct attgagcctg aattgctata
    17461 tggaatagct gaatgggggc tggcgccgtt attgcaagcc agtgatgcaa ccctctgtca
    17521 gaacgagccg ccaacatcct gcagtaatct accacatcag ctagcgttgc atattaaatg
    17581 gacagttgaa gaacatgagt tccatagcat tatttttaca tggccaacgg gttttttgcg
    17641 caatatagtc ggagagcttt ctgctgagcg tcaacagatt tatcctgctc ctcctgtggt
    17701 agtccctgta tatttaggct ggtgtcagct tacattaatt gaacttgagt ctatcgaaat
    17761 cggcatgggc gttcggattc attgctttgg cgacatcaga ctcggttttt ttgctattca
    17821 actacctggg ggtatttacg cgagggtgtt gctgacagag gataacacga tgaaatttga
    17881 cgaattagtc caggatatcg aaacgctact tgcgtcaggg agcccgatgt taaagagtga
    17941 tggaacgtct tcagtcgaac ttgagcagat accacaacag gtgctctttg agattggacg
    18001 tgcgagtctg gaaattggac aattacgaca acttaaaacg ggggacgttt tgcctgtagg
    18061 cggatgtttt gcgccagaag tgacgataag agtaaatgac cgtattattg ggcaaggtga
    18121 gttgattgcc tgtgggaatg aattcatggt acgtattaca cgttggtatc tttgcaaaaa
    18181 tacagcgtaa acctgataag aaaaataata tgcgaacaat ataatagcgt tccaggtcgt
    18241 gtcatgagag atacagtatg tctttacccg attcgccttt gcaactgatt ggtatattgt
    18301 ttctgctttc aatactgcct ctcattatcg tcatgggaac ctctttcctt aaactggcgg
    18361 tggtattttc gattttacga aatgctctgg gtattcaaca agttcctcca aatatcgcac
    18421 tgtatggctt cgcgcttgta ctttccttat tcattatggg gccgacgcta ttagctgtaa
    18481 aagagcgctg gcatccggtt caggtcgctg gcgctccttt ctggacgtct gagtgggaca
    18541 gtaaagcatt agcgccttat cgacagtttt tgcaaaaaaa ctctgaagag aaggaagcca
    18601 attattttcg gaatttgata aaacgaacct ggcctgaaga cataaaaaga aagataaaac
    18661 ctgattcttt gctcatatta attccggcat ttacggtgag tcagttaacg caggcatttc
    18721 ggattggatt acttatttat cttccctttc tggctattga cctgcttatt tcaaatatac
    18781 tgctggctat ggggatgatg atggtatcgc caatgaccat ttcattaccg tttaagctgc
    18841 taatattttt actggcaggc ggttgggatc tgacactggc gcaattggta cagagctttt
    18901 catgaatgat tctgaattga cgcaatttat aacgcaactt ttatggatcg tcctttttac
    18961 gtctatgccg gtggtgttgg tggcatcggt agttggtgtc atcgtaagtc ttgtccaggc
    19021 cttgactcaa attcaggacc aaacgctaca gttcatgatt aaattattag caattgcaat
    19081 aactttgatg gtcagctacc catggcttag cggaatcctg ttgaattata cccggcagat
    19141 aatgttacga attggagagc atggttgaat gacacaacag gtaaatgagt ggcttattgc
    19201 attggctgtg gcttttattc gaccattgag cctttcttta ttacttcctc tattaaaaag
    19261 tggcagttta ggggccgcgc ttttacgtaa tggcgtgctt atgtcactta cctttcccat
    19321 attaccaatc atttaccagc agaagattat gatgcatatt ggtaaagatt acagctggtt
    19381 agggttagtc accggagagg tgattattgg ttttttaatt gggttttgtg cggcggttcc
    19441 cttttgggcc gttgatatgg cggggtttct gcttgatact ttacgtggcg cgacaatggg
    19501 tacgatattc aattctacaa tggaagctga aacctcactt tttggcttgc ttttcagcca
    19561 gtttttgtgt gttattttct ttataagcgg cggcatggag tttatattaa acattctgta
    19621 tgagtcatac caatatttac cgccagggcg tactttatta tttgatcggc aatttttaaa
    19681 atatatccag gcagagtgga gaacgcttta tcaattatgc atcagcttct ctcttcctgc
    19741 cataatatgt atggtattag ccgatctggc tttaggtctt ttaaatcggt cggcacaaca
    19801 attgaatgtg tttttcttct caatgccgct caaaagtata ttagttctac taacgctcct
    19861 gatctcattc ccttatgctc ttcatcacta tttggttgaa agcgataagt tttatattta
    19921 tctaaaagac tggtttccat ctgtatgagc gagaaaacag aacagcctac agaaaagaaa
    19981 ttacgtgatg gccgtaagga agggcaggtt gtcaaaagta ttgaaataac atcattattt
    20041 cagctgattg cgctttattt gtattttcat ttctttactg aaaagatgat tttgatactg
    20101 attgagtcaa taacgttcac attacaatta gtaaataaac cattttctta tgcactaacg
    20161 caattgagtc atgctttaat agagtcactg acttctgcac tgctgtttct gggcgctggg
    20221 gtaatagttg ctactgtggg tagcgtgttt cttcaggtgg gggtgg
//
LOCUS       DAJVKX010000077        20185 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000077 DAJVKX010000000
VERSION     DAJVKX010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20185
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.077"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(90..383)
                     /locus_tag="OPY25_002871"
     CDS             complement(90..383)
                     /locus_tag="OPY25_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001667868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HCS0928443.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPDALMKGFGQPQLAMML
                     PLDGRKKLVNAELEKVKQALSEQGYYLQLPPPPEDLLKQHLSSVGQNTSHADR"
     gene            509..1216
                     /gene="minC"
                     /locus_tag="OPY25_002872"
     CDS             509..1216
                     /gene="minC"
                     /locus_tag="OPY25_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HCS0928444.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLK
                     HAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGK
                     EKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAE
                     LIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGK
                     AARLRLADNALTVQPLN"
     gene            1240..2052
                     /gene="minD"
                     /locus_tag="OPY25_002873"
     CDS             1240..2052
                     /gene="minD"
                     /locus_tag="OPY25_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HCS0928445.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLFILPASQTRDKDALTREGV
                     AKVLDSLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEYLLLTRYNPGRVNKGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDATADAGKAYADTVDRLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            2056..2322
                     /gene="minE"
                     /locus_tag="OPY25_002874"
     CDS             2056..2322
                     /gene="minE"
                     /locus_tag="OPY25_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HCS0928446.1"
                     /translation="MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK"
     gene            complement(2444..3571)
                     /gene="rnd"
                     /locus_tag="OPY25_002875"
     CDS             complement(2444..3571)
                     /gene="rnd"
                     /locus_tag="OPY25_002875"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HCS0928447.1"
                     /translation="MNYQMIETDDALASLCEAVRACPAIALDTEFVRTRTYYPQLGLI
                     QLFDGANVALIDPLGISDWSPLKAVLRDTGITKFLHAGSEDLEVFLNAFGELPEPLID
                     TQILAAFCGRPLSWGFASMVEEYTGVALDKSESRTDWLARPLSERQCEYAAADVWYLL
                     PIAKKLMIETEAAGWLPAALDECRLMQQRRQEIQAPEEAWRDITNAWQLRTCQLACLQ
                     LLADWRLRKARERDMAVNFVVREENLWAVARYMPGSLGELDSLGLSGSEIRFHGKTLI
                     SLVAKAQALPEEALPEPLLNLMDMPGYRKAFKAIKALVAEVSASHHVSGELLASRRQI
                     NQLLNWHWKLKPQNGQPELISGWRAELMAEKLTLLLQEYSL"
     gene            complement(3644..5329)
                     /gene="fadD"
                     /locus_tag="OPY25_002876"
     CDS             complement(3644..5329)
                     /gene="fadD"
                     /locus_tag="OPY25_002876"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HCS0928448.1"
                     /translation="MKKVWLNRYPADVPAEINPDRYQSLVELFEHAATRYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGAAAIIIVSNFAHTLEKVVEKTSVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALQHGYRMQYVKPEVVAEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVKATYGPLLHPGKELVVTALPLYHIFALTMNCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAMTGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQNVVAERWVKLTGQYLLEGYGLTECAPLVSVNPHDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVAPGEAGELCVKGPQVMLGYWQRPDATDEIIKDGWLHTGDIAVMDEDGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHSGVQEVAAVGVPSGSSGEAVKLFVVKKDPAL
                     TDDALITFCRRHLTGYKVPKQVEFREELPKSNVGKILRRELRDEARGKVDNKA"
     gene            complement(5534..6118)
                     /locus_tag="OPY25_002877"
     CDS             complement(5534..6118)
                     /locus_tag="OPY25_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein"
                     /protein_id="HCS0928449.1"
                     /translation="MAVQKRLIKGALACAFALMLSGCVTIPDAIKGSSPTPQQDLVRV
                     MNAPQLYIGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPVLGEASRGRIFADVN
                     GFLDPVDFRGQLVTVVGPITGTVDGKIGNTPYKFMLMQATGYKRWHLVQQVVMPPQPI
                     DPWFYGGRAWPYGYGGGWGWYNPGPAEVQTIVTE"
     gene            complement(6189..6884)
                     /gene="tsaB"
                     /locus_tag="OPY25_002878"
     CDS             complement(6189..6884)
                     /gene="tsaB"
                     /locus_tag="OPY25_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCS0928450.1"
                     /translation="MRILAIDTATEACSVALWNNGTINAHFELCPREHTQRILPMVQE
                     ILAASGASLNEIDALAFGRGPGSFTGVRIGIGIAQGLALGANLPMIGVSTLATMAQGA
                     WRKTGATRVLAAIDARMGEVYWAEYQRDAQGVWQGEETEAVLKPERVGERLKQLSGEW
                     ATVGTGWSAWPDLAKECGLTLHDGEVSLPAAEDMLPIASQKLAAGETVAVEHAEPVYL
                     RNEVAWKKLPGKE"
     gene            complement(6942..8852)
                     /locus_tag="OPY25_002879"
     CDS             complement(6942..8852)
                     /locus_tag="OPY25_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCS0928451.1"
                     /translation="MTDDFAADGQLAKAITGFKPREPQRQMAVAVTQAIENAQPLVVE
                     AGTGTGKTYAYLAPALRAGKKVIISTGSKALQDQLYSRDLPTVAKALAFTGKTALLKG
                     RSNYLCLERLEQQALAGGDLPVQTLSDVILLRSWSNQTRDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPLYKECFVVKARKKAMDADVVIVNHHLFLADMVVKESGFGELIPQ
                     AEVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLADSRIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRSRLKRLKEINQPGYSYWYECTSRHFTLALTPLTVADKFKEVMEQKPGSW
                     IFTSATLSVNDDLHHFTARLGIEQAESMLLPSPFDYTRQALLCVPRNLPQTNQPGAAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSAE"
     gene            8984..9328
                     /locus_tag="OPY25_002880"
     CDS             8984..9328
                     /locus_tag="OPY25_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HCS0928452.1"
                     /translation="MSIVRIDAEDRWSDVVIYNNTLWYIGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSSKSRILDATIFLSDKADFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
     gene            complement(9334..9513)
                     /locus_tag="OPY25_002881"
     CDS             complement(9334..9513)
                     /locus_tag="OPY25_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HCS0928453.1"
                     /translation="MFAGLPSLSHEQQQKAVERIQELMSQGMSSGEAIAQVAGELRAN
                     HTGERIVARFEDEDE"
     gene            9594..10958
                     /gene="pabB"
                     /locus_tag="OPY25_002882"
     CDS             9594..10958
                     /gene="pabB"
                     /locus_tag="OPY25_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HCS0928454.1"
                     /translation="MMKTLSPTVITLPWRPDAAEHYFAPVNHLPWAMLLHSGDAIHPY
                     NRFDILVADPVTTLTTRAQETTVCTARTTTVTLDDPLHVLQTQLEALPFHPQPDPDLP
                     FQGGALGLFGYDLGRRFEILPDTAARDIALPDMAIGLYDWALIVDHHKQVVSLISYHD
                     ADARYRWLTGQRAPTRTPFRLTSAWQSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQR
                     FQASYEGDEWQAFERLNRANRAPFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKG
                     TLPRLNDPQADRQQAQKLANSMKDRAENLMIVDLMRNDIGRVAVPGSVKVPELFVVEP
                     FPAVHHLVSTITARLPDSLHATDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWC
                     GSIGYLSFCGKMDTSITIRTVTATQGQLYCSAGGGIVADSNEEAEYQETFDKVNRILH
                     PLEN"
     gene            10962..11540
                     /locus_tag="OPY25_002883"
     CDS             10962..11540
                     /locus_tag="OPY25_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HCS0928455.1"
                     /translation="MDTSRLTLDHFLSRFQLLRPQMTHETLNQRQAAVLIPVVRRPQP
                     GLLLTQRAIHLRKHAGQVAFPGGAVDSTDASLIAAALREAQEEVAIPPQAVEVIGVLP
                     PVDSVTGFQVTPVVGIIPPNLPWRASEDEVSAVFEMPLAQALQLGRYHPLDVYRRGNS
                     HRVWLSWYEHYFVWGMTANILRELALQIGVKP"
     gene            11804..13168
                     /gene="sdaA"
                     /locus_tag="OPY25_002884"
     CDS             11804..13168
                     /gene="sdaA"
                     /locus_tag="OPY25_002884"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HCS0928456.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDNVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVETRERLLLAQGR
                     HEVDFPKDDGMRFHNGNLPLHENGMQIHAWHDDTVIYSKTYYSIGGGFIVDEAHFGQE
                     ATNEVTVPYPFKSAKEMLEYCNSTGLSLSGMVMQNELALHSKKEIEEYFGHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSSDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFLAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMAMRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            13306..14907
                     /locus_tag="OPY25_002885"
     CDS             13306..14907
                     /locus_tag="OPY25_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001192512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCS0928457.1"
                     /translation="MQTAQRIINHYRRNRFIVCTICALVTLILTLNIRFISERNLNHH
                     RTVAFANHAVDALDNVLHPLLVGRNILLPLLELPCATAHLPLRKQAARLQTIRSIGLV
                     KEGILYCSSIFGARNTPIRQLQPDLPAAGDLLLLSTDQSLLKGSPILIQWYPASADGQ
                     DGVMEIVNIDLLATMLLEPQQPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQL
                     SSRHFPFTISVSGPSAGVLAFKHLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINL
                     ALAEREFELFCQPLLNARTQQCTGVEILLRWNNPRQGWISPDVFIPITEEHNLIAPLT
                     RYVIAETIRQRHYFPINHQFHIGINVAASHFRHGVLLKDLNQYWFSAEPVQQLVLELT
                     ERDALLDVDYRLMRELHRKGVKLAIDDFGTGNSSLSWLEKLRPDILKIDKFFTAVIGT
                     DAVNSTVTDIIIALGQRLNIELVAEGVENQTQAQHLRQHGVQMLQGYLYAKPMPISEF
                     PQWLAGSAPPPARHNGQIMSAMPHL"
     gene            complement(14929..16488)
                     /gene="yoaE"
                     /locus_tag="OPY25_002886"
     CDS             complement(14929..16488)
                     /gene="yoaE"
                     /locus_tag="OPY25_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460784.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HCS0928458.1"
                     /translation="MELLMDPSIWVGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLIGLSLALIMRLALLSIISWLVTLTKSLFTVWDFTFSGRDLIMLLGGIFLLFKAT
                     TELHERLENREHDTGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIVIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQASMQHETDSPAAISV
                     SEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLSVAEIRQQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGADVAAIAASSPAIVVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIVADAEGWIVKGGTDLHALQ
                     QALEVDHLVNEEGDIATVAGLVIAANGHIPRVGDVIDVPPLRITIVEANDYRVDLVRI
                     VKEQPAHDEEE"
     gene            16961..17929
                     /gene="manX"
                     /locus_tag="OPY25_002887"
     CDS             16961..17929
                     /gene="manX"
                     /locus_tag="OPY25_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCS0928459.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTSKGVLFLVDTWGGSPFNAASRIVVDKERYEVIAGVNIPMLVETF
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPVAAAPKAATPAKPMGPNDY
                     MVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTAH
                     VVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERIVEGGVKVTSVNIGGMAYRQGKTQV
                     NNAVSVDEKDIEAFKKLNERGIELEVRKVSTDPKLKMMDLIAKVAK"
     gene            17982..18782
                     /gene="manY"
                     /locus_tag="OPY25_002888"
     CDS             17982..18782
                     /gene="manY"
                     /locus_tag="OPY25_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HCS0928460.1"
                     /translation="MEITTLQIVLVFIVACIAGMESVLDEFQFHRPLIACTLIGAVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTVLVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAAENGNLTALSWLHVSSLFLQAMRIAIPAVIVAI
                     SVGTSEVQGMLNAIPEVVTGGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGAVMAILYIQLSPKYNRVAGAPAAAAGNNDLDNELD"
     gene            18795..19646
                     /locus_tag="OPY25_002889"
     CDS             18795..19646
                     /locus_tag="OPY25_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HCS0928461.1"
                     /translation="MVDMTKTTTEKKLTPSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNDARKQAIKRHLEFFNTHPYIAAPVLGVTLAMEEKRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYRKGVDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVST
                     ITGQDGQTRVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     SVGLLGQ"
     gene            19705..20163
                     /locus_tag="OPY25_002890"
     CDS             19705..20163
                     /locus_tag="OPY25_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HCS0928462.1"
                     /translation="MTITDLVLILFIAALLAYALYDQFIMPRRNGPTLLSIALLRRGR
                     IDSVIFVGLVAILIYNNVTSHGAQMTTWLLSALALMGFYIFWIRTPRIIFKQRGFFFA
                     NVWIEYNRIKEMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLIENQ"
BASE COUNT         4715 a         5549 c         5172 g         4749 t
ORIGIN      
        1 aatcaagcaa ggcaccttgc cagttacgat gttgatacat attttcccct aagatcatga
       61 tggaattcag gcgcggcgcc gaataccgtt taacggtcag cgtgcgacgt attttgtccc
      121 accgaagaaa gatgttgttt cagcaaatct tccggcggcg gcggcaattg taaataatag
      181 ccctgctcgc ttaacgcctg ttttactttt tcgagctcgg cattgactaa ttttttacgt
      241 ccatcaagcg gcagcatcat cgctaactgc ggctgaccga atcctttcat caacgcgtca
      301 ggcacccgcg aaaaatcgtc ttttttttcg acatacaaat aggtttgatc gcgcttgcta
      361 cttctataga tcacacaaaa catactttta ctctgaatta acgggatggt gacttgcctc
      421 aatataatac tgactataac atgccttctg gacttcggaa tatcactccg tatcggagat
      481 gataaatagc aaattgagta aggccaggat gtcaaacacg ccaatcgagc ttaaaggcag
      541 tagcttcacc ttatcagtgg ttcatttgca tgaagcggaa ccagaggtta ttcgtcaggc
      601 gttagaagac aaaatagcgc aggctcctgc gtttttaaaa cacgcccctg tcgttattaa
      661 cgttagcggt cttgaaagcc cggtaaactg gccggaactg cataagatcg tgacctcaac
      721 cggcttacgc attatcggcg tgagcggctg taaagacgcc agcctgaaag tagaaatcga
      781 tcggatgggt cttcctttac tgactgaagg taaagagaaa gcggttcggc ctgcgcccgt
      841 tgagccggca acgcccagcg aaccgccgca aaacgctaat cccatcacaa aaacgcgatt
      901 aattgatgtt ccggttcgtt ccggtcagcg catttatgct ccacaatgtg atctgattgt
      961 tacaagtcac gtcagcgctg gcgcagagct tatcgctgac ggcaatatcc atgtctatgg
     1021 catgatgaga ggtcgcgcgc tggcaggggc gagcggcgat cgggaagcgc aaattttttg
     1081 tacccatctg acggcagaac tggtctctat cgcaggtgtt tactggctga gtgataaaat
     1141 cccggcagaa ttttatggca aagcggcgcg cctgcgttta gcagacaacg ctttgacagt
     1201 tcaaccgttg aattgatccc tttttaacaa ggaattttta tggcacgcat tattgttgtt
     1261 acttcgggta aagggggcgt tggcaagacc acctccagcg cggccatcgc tacaggtttg
     1321 gcccagaagg gaaagaaaac tgtcgtcatt gattttgata tcggactgcg taacctcgat
     1381 ctgattatgg ggtgcgaacg tcgtgtcgtt tacgattttg taaacgtcat tcagggcgat
     1441 gcgacactga atcaggcgct gatcaaagat aagcgtactg aaaatctctt cattcttccg
     1501 gcgtcgcaga cccgggataa agacgcgcta acgcgcgaag gcgtcgctaa ggtactggac
     1561 tcactgaaag caatggactt tgagttcatt gtttgcgact cgccggcggg tatcgaaacc
     1621 ggggcgctga tggcgctcta ttttgccgat gaagcgatca tcacgaccaa cccggaagtc
     1681 tcttctgtcc gtgactcgga ccgtattctg ggtattctgg catcgaaatc tcgtcgcgca
     1741 gaaaatggcg aagaaccgat taaagaatat ctcctgttga cgcgctacaa tccaggccgc
     1801 gtcaataaag gcgacatgct cagcatggaa gatgtactgg agattctgcg tattaaactc
     1861 gtcggtgtga tcccggaaga tcaatccgta ctgcgcgcat cgaaccaggg cgaaccggtg
     1921 attcttgacg ccactgcgga tgcgggtaaa gcctatgcag ataccgtaga tcgtctgttg
     1981 ggagaagaac gtcctttccg cttcattgaa gaagagaaga aaggtttcct caaacgcctg
     2041 ttcggaggat aaattatggc attactggat ttttttctct cgcggaaaaa gagtaccgct
     2101 aatattgcaa aagagcggtt gcaaatcatt gtcgcggaac gtcgccgtag cgatgccgaa
     2161 ccgcattatt taccgcagtt acgtaaagat attcttgagg tcatttgtaa atacgtacaa
     2221 atcgatccgg aaatggttac cgtccagctt gagcaaaaag atggtgatat ctccatcctt
     2281 gaacttaacg taacgctgcc ggaagccgaa gagtcaaaat aagctctttt atgggaaaat
     2341 tcctggatta aaaaaggcag aagaatctgc cttttttatt tttttacatt attccgaata
     2401 cggacattta tttcactggc cgttttcccg gcaattaccg tcgttaaagc gaatactcct
     2461 gcaacagaag agttaacttc tccgccatca gttcggcgcg ccagccggaa atcaattccg
     2521 gttgcccatt ttgcggtttt aatttccagt gccagttaag caactgatta atctgccgac
     2581 gcgatgccag tagctcgccg ctgacgtgat gcgacgcgct cacctccgcc actagcgctt
     2641 tgatggcctt aaacgctttg cgatagcccg gcatgtccat cagattcaac aggggttccg
     2701 gcaatgcctc ttccggtagc gcctgtgctt tcgccaccag cgatatcaac gtcttgccgt
     2761 gaaaacgaat ctcgctgccg gaaagcccca ggctatccag ctcaccgaga ctgcccggca
     2821 tataacgcgc gaccgcccac aggttttctt cacgcacaac aaagttcacc gccatatcgc
     2881 gctcacgcgc cttacgtagc cgccagtcag ctaaaagttg cagacaggct aactggcaag
     2941 tacgcagttg ccaggcattg gtgatatccc gccatgcttc ttccggcgcc tgaatctcct
     3001 gacgacgctg ctgcatcaat cggcattcat caagcgcggc aggcagccat cctgcggctt
     3061 cagtttcaat catcagcttt ttggcgatcg gtaacagata ccagacatcc gccgccgcgt
     3121 attcacactg acgttcgctt aaaggccggg ctaaccagtc ggtacgagac tcgcttttgt
     3181 ccagcgccac gcccgtatac tcttctacca tcgacgcaaa accccacgac agcggacgcc
     3241 cgcaaaacgc cgccagaatt tgcgtatcaa tcagaggttc cggcagttcg ccaaacgcat
     3301 tcagaaatac ttccagatct tcgctacccg cgtgcagaaa tttggtgatt cccgtatcgc
     3361 gcaacaccgc ttttaacggc gaccagtcgc tgatgccgag cggatcgatc agggcgacat
     3421 ttgccccgtc aaataactgg atcaatccta actgcgggta ataggtgcgg gtacggacaa
     3481 attccgtatc taaagcaata gccggacatg cgcggacagc ctcacacagg ctcgccagcg
     3541 catcgtccgt ttcaatcatt tggtaattca aatcgtgttc tctttggttc gcgccaaaaa
     3601 aaacgccggc ttaaccggcg tctctcgtta gctgacttaa cgctcaggct ttattgtcta
     3661 ctttgccacg ggcttcgtca cgcagttctc gtcgtaaaat tttcccaacg ttagattttg
     3721 gtaattcctc gcgaaactcg acctgtttgg gcaccttata tccggtcaga tggcgacggc
     3781 agaaggtgat caacgcatcg tcagtcaatg ccggatcttt cttaaccaca aaaagcttca
     3841 ccgcttcgcc gctactaccg gaaggcacgc caaccgccgc gacttcctgc acgccagaat
     3901 gctgcatcac cacatcttca atttcgtttg gataaacgtt gaaaccagaa accagaatca
     3961 tatctttctt acgatcgaca atccgcagaa agccgtcttc atccataacc gcaatatcgc
     4021 ccgtatgcag ccagccatct ttaatgattt catccgtcgc gtcaggacgc tgccagtatc
     4081 ccagcataac ctgcgggcct ttcacgcaaa gctctccggc ctcacccggc gcgacttcgt
     4141 tgtcatcgtc atccaccagt ttggcttctg ttgacggtac tggcaggccg atactgccgc
     4201 tgtgataatc aatatcatgc gggttgacgc tcaccagcgg ggcgcactcg gtcagcccgt
     4261 agccttccag caggtattgc ccggtcagct ttacccaacg ttccgcaacg acgttttgca
     4321 ccggcatccc gccgccggct gacagatgca gcgaagaaaa atccagctgt tgaaactctt
     4381 tattattgag cagggcgttg aatagcgtat taacgccagt catcgccgta aatggatatt
     4441 tcgccagctc cttgaccaga ccggggatat cacgcggatt ggtaatcagc aggttttgcc
     4501 cacccagctc gataaaaagc agacagttca tggttaaggc aaaaatgtga tacagcggca
     4561 gcgcggtcac taccagctct ttccccgggt gcagcagcgg cccataggtc gctttcacct
     4621 gctccagatt cgccagcata ttgcggtggg tcaacatcgc gcctttcgcc acgcccgtcg
     4681 taccgccagt atattgcagg aaagccagat cttcagcgac aacctcgggt ttgacatact
     4741 gcatacggta gccatgctgt agcgcgctgc gaaacgagat cgcatctggc aagtggtatt
     4801 ttggcaccag acgcttgatg tatttcacga caaagttaac aaccgtacct ttggcggtag
     4861 aaagctggtc gcccatccgc gtcagaataa cgtgctgtac cgacgttttc tcgaccactt
     4921 tttccagcgt atgggcaaag ttagaaacaa taatgattgc cgccgcgccg ctatcgttaa
     4981 gctgatgctc aagttcgcgc ggcgtgtaaa gcgggttaac gttcaccaca atcatgccgg
     5041 cgcgtaaaat accaaatagc gcgacaggat actgcaacag gtttggcatc atcagcgcca
     5101 cacggtcgcc ttttttgagt cccagccctt gttgtaaata agccgcaaat gcccgactac
     5161 gttcttctaa tttacggaag gtcattacct cccccatatt gacgaacgca ggctgatcgg
     5221 catagcgcgt cgccgcatgt tcaaacagtt caaccaggga ttgataacgg tcagggttga
     5281 tctccgccgg aacatcagca ggataacggt taagccaaac cttcttcaat gcatcacctc
     5341 taaaatgagt gttcgtcgtc atcacaaccc cagtcaataa acaagtcgtt aacattatat
     5401 taactcagcg taccagttta ttaattacgc aactgaaagg ttgcgaagcg cgtcactatt
     5461 tatttttatt atgtctctat gaatgcagaa acagcggacc agccgctgtt tcttttattg
     5521 ataaaacaaa gggttactct gttactatcg tctgaacctc tgcgggtcca gggttatacc
     5581 atccccaacc gccgccatat ccataaggcc aggcgcgtcc gccgtaaaac cacggatcga
     5641 tcggctgtgg aggcatgacg acctgctgaa caagatgcca gcgtttatag ccggtagcct
     5701 gcatcagcat aaatttatac ggcgtattgc cgattttacc gtcaaccgtg ccggttatcg
     5761 ggccgacaac ggtaactaac tggccacgga agtccaccgg gtccagaaaa ccgttcacat
     5821 cggcaaaaat tctgccgcgc gaggcttcgc ccagaacagg acgcgcgccg ctgtcgagcg
     5881 gtacggtcgc gatttcaagc cgggtttttc cctgctgatt ttgtaccgcc acaactttgc
     5941 cgccaaaacg cgcctcttgc ccgatataga gctgcggcgc attcatcacc cgcaccaaat
     6001 cctgctgcgg cgtcggactc gaacctttaa tggcatccgg gatagtcacg caaccgctca
     6061 gcataagcgc aaaagcgcac gccagcgccc cttttattaa ccgtttttga accgccatga
     6121 tgcgactcct ttttctcgac ctctattcca ccccacagca taaagtatgg gggtaatagt
     6181 agtgagagtc attctttgcc gggaagtttc ttccacgcca cttcgttacg caaataaacc
     6241 ggctcggcat gttccacggc aacggtctct cctgccgcca gcttttgact ggcgatgggc
     6301 aacatatctt ccgctgccgg gagcgacacc tccccatcat gaagcgtcag gccgcactcc
     6361 ttcgccagat cgggccatgc ggaccaaccc gttcctacgg tcgcccactc gccggaaagc
     6421 tgtttcaacc gctcgccgac ccgttccggt ttcagcaccg cttccgtctc ttcgccctgc
     6481 cagacgccct gcgcatcacg ctggtattcc gcccagtaca cttcgcccat ccgcgcgtca
     6541 atcgcggcga gtacgcgggt cgcgccagtt ttacgccatg cgccctgcgc catcgtggca
     6601 agcgtcgaaa caccgatcat cggcagattt gcccctaacg ccagcccttg cgcaatccca
     6661 atgccgatac gcacgccggt aaagctgccc ggaccgcgcc caaacgccag cgcatctatc
     6721 tcattgagcg aggcgccgct ggcggccaga atctcctgca ccatgggcag gatacgttga
     6781 gtgtgttctc gtggacaaag ctcaaagtga gcattgatag taccgttgtt ccacagggcg
     6841 acagaacagg cctctgtggc ggtatcgata gccagaattc gcatgaggtt tcgtgcttag
     6901 atcaataaaa tagcgcgcat cttaccatac tccgtaacaa attactcggc ggatggaatc
     6961 gcaagaaagc gaacggcacg ggcgatatca cgcgtgcgcg gcgcaggagg caggctggcg
     7021 agaaacgtgg cgccataggg ccgcatcacc agccggttat cacaaatcac taacaccccg
     7081 cgatcgtccg catcgcgaat tagccgcccc actccctgct tcagcgtaat caccgcatcg
     7141 ggcagttgaa cctcatcaaa cggatcgcca ccgcgcaaac gacagtcttc cattcgcgct
     7201 tttaacagcg ggtcgtccgg ggaagtaaac ggcaatttgt cgataatcac caaagataac
     7261 gtatcgccgc gcacgtccac cccttcccag aagctgctgg tggcgacgag cagcgcgttg
     7321 ccggcgctaa caaattgctg taacagttgg cctttactgg tttccccttg caacaatacc
     7381 ggcagcgtca tggtggcgcg aaactgctcc gccagatcgc gcatcatggc gtgtgaggtg
     7441 cacagcataa aacatcgccc gttattggct tcgataatcg gcctgagcat agccgccaac
     7501 tgtcgcgccg cgccgggctg gttggtttgc ggtaggttac gcggtacgca gagtaacgcc
     7561 tggcgcgtat agtcgaatgg gctgggcagc agcatggatt ctgcctgttc aattcccaga
     7621 cgggcggtaa agtggtggag atcatcattt accgacaacg tggccgaggt aaaaatccag
     7681 ctaccgggct tctgttccat cacctctttg aatttgtccg ccacggtgag cggcgtcagc
     7741 gccagagtga aatggcgcga ggtgcactca taccagtagc tgtatcccgg ctgattgatc
     7801 tcttttaagc gtttcagccg tgaacggtat agcgtggcgc gttcaaaagc cgcatccagc
     7861 agcgccgaac ggcccagcga cagtttcgcc acgtcgtaac aaagctccag cgtatcatcc
     7921 agcagtaaaa atgcccgttg gatacgagag tcggctaaca gttcacgcaa atttccccgg
     7981 tagccgggct cccccagttg cagacgaaaa tcctgggcgc tctgggcaag gcgatcggcg
     8041 catttttgca actgttgagt gtctttcagt tccgtccggt aggcgatggt gatgtctttt
     8101 gctaaatcca gcaactgacg gctagagagc gattgtccga aatactggct ggcgatgtca
     8161 ggcagttggt gggcttcatc gaagatcatt acttcagcct gagggataag ttcgccaaac
     8221 ccgctctctt taaccaccat atccgcaaga aaaaggtggt ggtttacaat caccacatcc
     8281 gcgtccatcg cctttttacg cgctttcacc acaaagcact ctttgtaaag cggacaatcg
     8341 ctgccaaggc agttgtcgtt ggtactggtg accagcggcc aggcctggga atcctccgcc
     8401 acgctgacgc aggtgctgat atcgccatcc cgcgtctgat ttgaccagga gcgcagcaat
     8461 atcacgtcgc ttaacgtttg taccggtaaa tcgccgcccg ccagcgcttg ttgttccaga
     8521 cgctccaggc agaggtagtt tgaacgtcct ttcaacaggg ccgtcttacc ggtaaacgcc
     8581 aacgcttttg ctaccgtcgg cagatcgcgg ctgtagagtt gatcctgcaa cgctttcgac
     8641 ccggtcgaaa taatgacttt tttcccggcg cgcaacgccg gagcgaggta agcataggtc
     8701 ttcccggttc cggtgccggc ttcaacaacc aaaggctgcg cattttcaat cgcttgtgtc
     8761 acggcaaccg ccatttgtcg ctgtggttcg cgcggtttaa agccggttat cgctttggcc
     8821 agttggccat ctgctgcaaa atcgtccgtc acactgcccc ctgttaattt gcacagggga
     8881 ttatgtcagg gtagaaaggc ttacgccagt tacagaggtg acggcggcgc cacattgtgg
     8941 cagtcttgag ccattcaaat ggaaagcaaa tgaggaataa gtgatgtcta tcgtgcgtat
     9001 tgatgccgaa gatcgttggt cagacgtggt gatctacaat aatacgctgt ggtatatcgg
     9061 cgtgccggaa aacctggacg ccgatgcttt tgagcaaacg gcgaatactc tggcgcaaat
     9121 tgatgcggtg ctggaaaaac agggctccag taagtcacgt attctggatg ccactatttt
     9181 cctgagcgat aaagcggatt ttgccgccat gaataaggcg tgggatgcgt gggtcgtcgc
     9241 aggccatgcg ccggtacgct gtaccgtaca ggccgggttg atgaacccga aatataaagt
     9301 tgagattaag attgtcgcgg cggtataagc cggttattcg tcttcatcct caaaacgcgc
     9361 cactatccgt tcgccggtat ggttggcgcg aagttcgcct gccacctggg caatcgcttc
     9421 tccgctactc ataccttgcg acatcaattc ctggatacgt tctacggctt tttgctgttg
     9481 ttcatgactg agtgaaggta aacctgcaaa catgattaac tcctgctaaa ttgttagcgc
     9541 taattatttc acgctacccg gcggtaagcc agtagtgttg taacgagtca ggaatgatga
     9601 agacgttatc tcccactgtt atcaccttac cctggcgtcc ggacgccgct gaacactatt
     9661 ttgcgcccgt aaaccatttg ccctgggcga tgctgctgca ttcaggtgat gctattcatc
     9721 cctataaccg ttttgatatt ctggtcgccg atcctgtcac cacactgacc acgcgcgccc
     9781 aggaaaccac ggtatgtact gcgcgcacga ctaccgtcac tctcgacgat ccgttacacg
     9841 ttttgcagac tcaactggag gcgctgcctt ttcatcctca gcctgaccct gacttaccct
     9901 ttcagggcgg cgcgctgggt ctgtttggtt atgatttagg gcggcgtttc gaaattctgc
     9961 ccgatactgc cgcgcgcgat atcgctttac ccgatatggc gattggcctt tacgactggg
    10021 cgctgattgt cgatcaccat aaacaggtag tgtcgctgat aagctatcac gatgcagacg
    10081 cccgatatcg ctggctcacc ggccagcgcg cgccgacccg aacgcccttc aggcttacct
    10141 cggcctggca atccaatatg acgcgttgcg agtatggcga gaagtttcgt caggtgcagg
    10201 cctggctgca cagcggggac tgctatcagg tcaatctttc ccagcgtttt caggcgagct
    10261 acgagggtga tgaatggcag gctttcgaac gccttaaccg cgcaaatcgc gccccgttca
    10321 gcgcctttct tcgtttacat gacggcgcca tattgagcct ttctcccgag cgttttatcc
    10381 aactggagaa cggtcatatt cagacgcgcc cgatcaaagg tacgcttcca cggcttaacg
    10441 atccgcaggc ggatcgtcag caggcgcaga aactggctaa ttcaatgaaa gatcgcgctg
    10501 aaaatttgat gattgtcgat ttgatgcgta acgacattgg ccgggtcgcc gtaccaggtt
    10561 cggtgaaagt gccggaactg ttcgtcgtcg aaccatttcc tgccgttcac catctggtta
    10621 gcaccattac tgcccgttta ccagactcgc ttcatgccac cgatctgctg cgcgcggctt
    10681 tccccggcgg ctccattacc ggcgcgccta aagtgcgggc aatggaaatt atcgacgaac
    10741 tggagccgca gcgacgcaac gcctggtgcg gtagcatcgg ttatctgagt ttctgcggca
    10801 agatggatac cagtattact atccgcaccg tcacggcaac gcagggccaa ctctattgct
    10861 cagccggcgg cggtatcgtg gccgatagca acgaagaagc ggaatatcag gaaacttttg
    10921 ataaagttaa tcgtatcctg cacccactgg agaactaata cgtggatacc agccgtctga
    10981 cgctcgatca tttcttatcg cgctttcagc ttttgcgccc gcagatgact catgaaacgt
    11041 taaatcaacg tcaggccgcc gtactgatcc ctgtggttcg ccgcccccag ccggggctgc
    11101 tgttgaccca gcgggctatt catttgcgca aacacgccgg acaggtcgcc tttcccggcg
    11161 gggccgtgga cagtaccgat gcttcgctta tcgccgcagc gcttcgcgaa gcgcaggagg
    11221 aagtcgccat cccgccgcaa gccgtggaag tgattggcgt tttaccgccg gtagacagcg
    11281 tgaccggttt tcaggtcacc ccggtggtcg gcattattcc gccaaatctc ccctggcgcg
    11341 ccagtgaaga cgaagtgtct gcggtgtttg aaatgccgct ggcgcaagcg ttgcaactgg
    11401 gtcgatatca tccgcttgat gtttaccgtc gcggcaattc gcaccgcgta tggctctcct
    11461 ggtatgagca ttatttcgtc tggggcatga ccgcaaacat tcttcgtgag ctggcgctgc
    11521 aaatcggcgt aaagccctga ctgtacacaa cgccattcac gttgcctcaa ggcggtaaca
    11581 atcgcctccc ccaaagaggc agcctgaagg gcaacgtgta tatacttaac tttacgcgcg
    11641 caagacacga cttgagatta ctgtcgcaat attagtaaaa acgcggttat tcattagttt
    11701 aattcatgtg aatagttaag ctgatgccag cgttccctct tacactatgc gcagttataa
    11761 catcgtaacc ggaagccccg gttgccctgt caggagtatt atcgtgatta gcctattcga
    11821 catgtttaag gtagggattg gtccctcctc ttcccacact gttggcccga tgaaggccgg
    11881 taaacagttc gtcgatgacc tagtcgaaaa aggattactg gataacgtta cccgcgtcgc
    11941 tgtcgatgtc tacggctcgc tgtcgctgac ggggaaaggt caccataccg atatcgccat
    12001 tattatgggt ctggcgggta atgaacccgc taccgtggat attgatagta tccccggttt
    12061 tattcgcgac gtcgaaacgc gcgagcgtct gttactggcc cagggacgtc acgaagtcga
    12121 cttcccgaaa gatgacggaa tgcgttttca caacggcaat ttgccgctgc atgaaaacgg
    12181 gatgcagatc cacgcctggc atgacgacac ggtcatttat agcaagacgt actattccat
    12241 cggcggcggc tttatcgttg atgaagcgca tttcggccag gaagcgacga atgaggttac
    12301 tgtaccttat ccgtttaaat cggcgaaaga aatgctggag tattgcaaca gcaccggcct
    12361 ttcactctcc ggcatggtga tgcaaaacga actggcgctg catagcaaga aagagattga
    12421 agagtatttc ggtcacgtct ggcaaaccat gcaggcttgt attgatcgcg gtatgaatac
    12481 cgaaggcgtt ctgccggggc cgctgcgcgt accgcgtcgc gcctctgcgc tgcgtcgtat
    12541 gctggtttcc agcgataagc tttccagcga tccgatgaac gtcattgact gggtgaacat
    12601 gtttgctctg gcggtgaacg aagagaacgc cgcaggcggt cgcgtcgtga cggcgccaac
    12661 caacggcgcg tgcggcatcg ttcctgcggt actggcttac tacgaccatt ttattgagtc
    12721 tgtcagcccg gatatttaca cccgctactt cctggcggca ggcgctattg gcgcgctgta
    12781 taagatgaac gcgtctattt ccggcgcgga agtcggctgt cagggcgaag tcggggtcgc
    12841 ctgttcgatg gcggcggcag gccttgctga actgttgggc gccagcccgg aacaggtttg
    12901 cgttgccgct gaaatcggca tggagcataa cctggggctg acctgcgacc cggttgccgg
    12961 tcaggtgcag gtgccgtgta tcgagcgtaa cgccattgct tcggttaaag cgatcaacgc
    13021 tgcgcgtatg gccatgcgtc gaaccagcgc gccgcgcgtc tcgctggata aagtcatcga
    13081 aacgatgtac gagaccggaa aagacatgaa cgccaaatac cgcgaaacgt cgcgcggcgg
    13141 gttggctatt aaagtccagt gtgattaaac gccatttccc ctcccttcgc ccatctgcta
    13201 cggatgggcg aaatttttat ctcttcctcg tcgactccac gtttccccac tacacttgct
    13261 gtgtcgcggt tggcttttgt cgccaacgct tattgggcgg cccgcatgca aacagcacaa
    13321 cggatcatca atcattatcg ccgtaatcgt ttcattgttt gcacgatttg tgcactggtc
    13381 acgctcattc ttacgctgaa catccgattt atttcggagc ggaacttaaa tcaccatcgc
    13441 acggttgcat tcgcgaatca tgccgttgat gcgctggata atgtgctgca tcctctcctg
    13501 gtcggacgaa acatactgct acccttactt gagcttccgt gcgcgaccgc gcatctgccg
    13561 ttgcgtaagc aagccgcccg cctgcaaacc attcgttcta tcgggctggt aaaagaggga
    13621 attctctact gctcaagcat ttttggcgcc cgtaatactc ccatacgcca gcttcagccc
    13681 gatcttcccg cagctggcga tctgctgcta ctttccacgg accaatcgtt actcaaggga
    13741 agcccgatcc tcattcagtg gtatcccgcc tctgccgatg gacaggatgg cgtgatggaa
    13801 attgtgaata ttgacttgct ggcgactatg ctacttgagc cgcagcagcc gcaaattacc
    13861 agcgccagcc tgacggtcgg caaacggcac ctgttatatg gtcggggcgt ggtcgatact
    13921 cttccggaat taaaaaaaga tgaagagcgt taccagcttt catcgcggca tttccctttt
    13981 actatcagcg tcagcgggcc gtcggcaggc gtactggcgt tcaaacatct cccgacgcag
    14041 ttaccgctgg ccgtattgct tagcctgttg atcggttata tcgcctggct ggcaaccgcc
    14101 agcagaatga gcttttcctg ggaaattaat ctggcccttg ccgaacggga gtttgagcta
    14161 ttttgtcagc cgttgcttaa tgcccgcacg cagcagtgta ccggcgttga gatcctgtta
    14221 cgctggaata acccgcgcca gggctggatc tcaccggatg tttttattcc tatcaccgag
    14281 gagcataacc tgatagcgcc gctgacccgc tatgtgattg cggaaaccat tcggcagcgg
    14341 cactacttcc ccatcaacca tcagtttcat atcggcatca atgtggcggc aagccatttc
    14401 cgacacggcg tgcttctcaa ggatcttaat cagtactggt ttagtgcgga acctgttcag
    14461 caactggtgc tggagctcac ggaacgcgac gcgttgcttg acgttgatta ccgcctgatg
    14521 cgcgagctgc atcgtaaagg cgtgaagtta gccatcgatg attttggcac aggaaacagc
    14581 tcgctctcct ggctggaaaa actgcgtccg gatattttga aaatcgataa attcttcacc
    14641 gccgtcatcg gtaccgatgc ggtcaattca acggtgaccg atattattat cgcgctgggg
    14701 caaagactga atattgaact ggttgcggaa ggggtcgaaa accagacgca ggcacagcat
    14761 ttgcgccagc atggcgtgca aatgttacag ggctatctct atgcgaagcc gatgcccatt
    14821 agcgaatttc cacagtggct ggcgggcagc gcgccgccgc ccgcccggca taacggacag
    14881 attatgtccg cgatgccgca tctatagact tgattcctgc gtgtgacgtt attcctcttc
    14941 gtcgtgggca ggctgttctt taacaattcg aaccagatcg acacggtagt cgttagcctc
    15001 gacaatggtg atccgcaggg gcggaacatc aatgacatcg cctacacgag gaatatggcc
    15061 attagcggcg atcactaacc ccgcgaccgt cgcaatatca ccctcttcgt tcaccagatg
    15121 gtcaacttcc agcgcctgct gtaacgcatg aagatcggtg ccgcccttca ctatccagcc
    15181 ctcggcatcg gcaacgattt ccggcgtttc atcggcatcc gggaactcac cggcaatcgc
    15241 ttccagcaca tccagcggcg taaccagccc ctgcaccacg ccgaactcgt tagtgacgat
    15301 aacgaaactg ccgcgcgcgc gacgcaaaac gcctaacaga ttgataggat caagcgtttc
    15361 cggcaccact atcgccgggg aagaggcggc gatagccgca acgtccgcgc cctcttccag
    15421 cgccaccagc aactctttcg cccgaacgat accgataatt tcatccagct cgccccgaca
    15481 taccgggaac aggctatgcg gagaagagag taactgctga cggatttcag ctacgctgag
    15541 attcgcatcc acccaactaa tttcgcctcg cggcgtcata atgccgcgca gggagcgcga
    15601 cgccagagtc agtacgccgt taatcatgta gcgttcttct tcggcgaagg cgccttccga
    15661 caccgatatc gcggccgggc tatccgtctc atgttgcata ctcgcctgac gtttaccgcc
    15721 catcagacgc aggatagcgt ccgcagtacg cgcgcgcagc ggcaacgtgg actgatgacg
    15781 aataaagttg cggcgcgcaa tctggttaaa cacctcgata acgatcgaga aaccaattgc
    15841 cgcgtacagg tagcctttcg gaatatggaa accaaatcct tccgccacca ggctcaagcc
    15901 gatcatcagc aggaaactca gacagagcac caccaccgtc ggatgctggt tgacaaaacg
    15961 ggtcagcggt tttgacgcca gtagcatcac cgccatcgca atcaccaccg ccgccatcat
    16021 aaccggcaga tggtttacca tacctaccgc cgtaatcacg gcgtccagcg agaagaccgc
    16081 atccaggatg acaatctgcg tgactaccac ccagaagctc gcatagcctt taccgtgtcc
    16141 ggtgtcatgc tcgcggtttt ccagacgttc atgcagctcg gtggtcgctt taaacagcag
    16201 gaatataccg cccagcagca taattaaatc gcggccggag aaggtaaaat cccagacagt
    16261 aaagagcgac tttgttaagg tcaccagcca cgaaataatg gacagcagcg ccagacgcat
    16321 aatcagcgcc agcgagagcc cgataagacg cgctttgtca cgctgctttg gcggcaattt
    16381 atcggcgagg atcgcgataa agaccaggtt atcgataccc aggacaattt ccaggacgac
    16441 gagcgtgagt aaacccaccc aaattgaggg atccattaat aattccatga caagctcctg
    16501 cttaaggaat gactaaacgg cgcccacaac atctcaaagg atgcaggcgg taacgcaata
    16561 aacaaagtaa ggctatggca agatatgcca gattgacagg cgcaaaacgg ccaaagagtg
    16621 aaatgacgtc ggtgacgatc catacaacgg gctgctgccc tataccccat tctaattaaa
    16681 cggaagctaa acataacaga gacaactggt ttttggcaaa gatttacctt cctttgcaaa
    16741 gagatgtaac caggatattt tacacttcga aatttctcat tatcgaaaac aaaattacag
    16801 atctccatca cacaaaatat ttttttcgat atctaaaata attcacgaaa atcatgcgtt
    16861 tttcgttgta accctcatct gaatcgattc gcttgcggac ggcgattcaa aaaatacatc
    16921 tgtcaagttg atgtgttgac aataataaag gaggtagcaa gtgaccattg ctattgttat
    16981 aggcacacat ggttgggctg cagagcagtt acttaaaaca gccgaaatgc tgttaggcga
    17041 gcaggaaaac gtcggctgga tcgatttcgt tccaggcgaa aatgccgaaa cgctgatcga
    17101 aaagtacaac gctcagttgg ctaaactcga taccagtaaa ggcgtgctat ttctcgttga
    17161 tacatgggga ggcagtccgt ttaatgctgc cagccgcatt gtcgtcgata aagagcgcta
    17221 tgaagttatt gccggcgtca acatcccgat gctggtcgaa acgtttatgg ctcgtgacga
    17281 cgatccgagc tttgacgagc tggtcgcact ggcggtagaa accggtcgtg aaggcgtaaa
    17341 agcgctgaaa gcgaaaccgg tagaaaaagc cgcgccagcg ccggtcgccg ccgcgccaaa
    17401 agcggccacg ccggcaaaac cgatgggccc gaatgattat atggttatcg ggcttgcccg
    17461 tattgatgac cgcctcattc acggtcaggt cgctacccgc tggaccaaag agaccaatgt
    17521 cagccgtatt attgttgtga gcgatgaagt cgcggcggat accgtacgta aaacgctgct
    17581 gacgcaagtt gcgccgccgg gcgttacggc gcatgtggtt gacgtcgcga agatgattcg
    17641 cgtctacaat aacccgaaat acgccggcga acgcgtgatg cttctgttta ccaatcctac
    17701 cgacgtcgag cgcatcgttg agggcggcgt gaaagtcacc tccgtgaaca ttggcggtat
    17761 ggcctatcgt caaggtaaaa cgcaggtgaa caacgccgtt tccgtcgatg aaaaggatat
    17821 cgaagccttt aaaaagctca acgagcgcgg catcgagctt gaggtgcgta aagtttccac
    17881 cgatccgaaa ctgaaaatga tggatttaat tgccaaagtg gcgaaataac cgccggcatt
    17941 taattagctt tcacacttaa gatagcaata ggagaagtac aatggagatt accactcttc
    18001 agattgtgct ggtgttcatc gtcgcatgta tcgcgggtat ggagtcggta cttgatgaat
    18061 ttcagttcca ccgtccgctg atcgcctgta ccttaatcgg cgccgttctg ggggacatga
    18121 aaaccggtat tatcatcggc ggtactctgg aaatgatcgc tctgggctgg atgaacatcg
    18181 gtgctgccgt tgcgcctgat gccgcactgg cgtccatcat ctctaccgtt ctggtcatcg
    18241 ctgggcatca aagcattggc gccggtatcg cgctggcgat tccgctggcg gcggcaggcc
    18301 aggtactgac cattatcgtt cgtaccatca ccgtggcatt ccagcacgcg gcggacaagg
    18361 cggctgaaaa cggcaacctg acggcgctct cctggctgca cgtttcttct ctgttcctgc
    18421 aggcaatgcg tatcgccatc ccggcggtta tcgttgccat ctccgtaggc accagcgaag
    18481 tacagggaat gctgaatgcg attcctgaag tcgtcacagg cggtctgaac atcgccggcg
    18541 gcatgatcgt cgtggttggt tatgcgatgg ttatcaacat gatgcgcgca ggctacctga
    18601 tgccgttctt ctacctcggt ttcgtcaccg cggctttcac aaacttcaac ctggtcgcac
    18661 tgggtgtcat cggcgcagtg atggctattc tttacatcca gctgagcccg aaatacaacc
    18721 gtgtagcggg cgcgcctgca gcggctgctg gcaataacga tctcgataac gaactggact
    18781 aacaggtgag cgaaatggtt gatatgacta aaactaccac cgagaaaaaa ctcactccga
    18841 gcgatattcg cggcgtattt cttcgttcta acctgttcca ggggtcatgg aacttcgaac
    18901 gtatgcaagc gctgggcttc tgcttctcta tggtgccggc gattcgtcgc ctgtatccgg
    18961 agaataatga cgcgcgtaaa caggcgatta agcgtcacct ggagttcttt aacactcatc
    19021 cttacattgc ggcgccggta ctgggcgtaa cgctggcaat ggaagaaaag cgtgcgaacg
    19081 gcgcagagat tgacgatggt gctatcaacg gtatcaaagt cggtctgatg ggaccgctgg
    19141 caggcgtcgg cgaccctatc ttctggggta ccgtccgtcc agtattcgcg gcgctgggcg
    19201 caggtattgc aatgagcggc agcctgcttg gtccgctgct gtttttcatc ctgtttaacc
    19261 tggtgcgtct ggcgacccgt tattatggcg tggcttatgg ctaccgcaaa ggcgtcgata
    19321 tcgttaaaga tatgggcggc ggcttcctgc aaaaactgac tgagggggcg tcaatcctcg
    19381 gcctgtttgt catgggggca ttggttaaca agtggacgca tgtgaatatc ccgctggtgg
    19441 tctccaccat caccggtcag gatggtcaga cacgcgttac caccgtgcaa accattctcg
    19501 accagctgat gccgggtctg gttccgctac tgttgacctt tgcctgtatg tggctgctgc
    19561 gtaagaaagt taacccgctg tggattatcg tgggcttctt cgtcattggt atcgccggct
    19621 actccgtagg actgctgggc cagtaaggct gttgtacact accggggcca aacggccccg
    19681 tttttttatt tctctggagg ataaatgact atcacggacc tggtgctgat tctctttatt
    19741 gccgcattat tggcttacgc tctctacgat cagttcatca tgccccgtcg caatggcccc
    19801 actctgcttt ctatagccct gctccgccgc ggtcgcatag acagcgttat cttcgttggg
    19861 ctggtcgcca tccttattta taacaacgta accagccacg gagcgcagat gaccacatgg
    19921 ttattaagcg cgctggcgtt aatggggttt tatatattct ggatccgcac gccacggatc
    19981 atctttaaac aacgtggctt tttcttcgcc aatgtctgga tagaatataa ccgtattaaa
    20041 gagatgaatt tatcggagga cggcgtactg gtgatgcaat tagaacaacg acgcttgctt
    20101 atccgtgtac gcaatatcga cgatctggaa aaaatatata aacttcttat tgaaaatcaa
    20161 tagcttaaga tatagcctca actat
//
LOCUS       DAJVKX010000078        20087 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000078 DAJVKX010000000
VERSION     DAJVKX010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20087
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.078"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..282)
                     /locus_tag="OPY25_002891"
     CDS             complement(<1..282)
                     /locus_tag="OPY25_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928463.1"
                     /translation="MKLIIILLLALFPLCSSASNHYALVFENNTILLVLNLKCSPCDL
                     NCANIQYQLFNKETESVISGAAKPVTTGIENNFRGYMMRNNNTFYSLIES"
     gene            complement(506..581)
                     /locus_tag="OPY25_002892"
     tRNA            complement(506..581)
                     /locus_tag="OPY25_002892"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(546..548),aa:Thr,seq:cgt)
     gene            complement(697..1947)
                     /gene="proA"
                     /locus_tag="OPY25_002893"
     CDS             complement(697..1947)
                     /gene="proA"
                     /locus_tag="OPY25_002893"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCS0928464.1"
                     /translation="MLEQMGIAAKAASYKLALLSSCEKNRVLEKIADELEAQMESILS
                     ANVQDVEQARANGLSEAMLDRLALTPARLKAIADDVRQVCNLADPAGQVIDGGLLDSG
                     LRLERRRVPLGVVGVIYEARPNVTVDVASLCLKTGNAVILRGGKETHRTNAATVLVIQ
                     KALKACDLPEAAVQAIDNPDRSLVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIFVDSSADIAPALKIIVNAKTQRPSTCNTVETLLVHQDIAERFLPALSKQ
                     MAESGVTLHGDETVMQALHGPAKLVALKPEELDNEFLSLDLNVVVVENMDGAIAHIRE
                     HGTQHSDAILTCDMHNAARFVNEVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHA
                     RGPMGLEALTTYKWIGFGDGTIRA"
     gene            complement(1959..3062)
                     /gene="proB"
                     /locus_tag="OPY25_002894"
     CDS             complement(1959..3062)
                     /gene="proB"
                     /locus_tag="OPY25_002894"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCS0928465.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQML
                     LTRADMEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQQGLFTADPRSNPQAELIKDVYGVDDALRSIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIASGSKPGVIGDVMEGISVGTRFHAQASPLENRKRWIFGAPPAG
                     EITVDEGATAAMLERGSSLLPKGIKSVTGNFSRGEVIRICNLQGRDIAHGVSRYNSDA
                     LRRIAGHHSQQIDAILGYEYGPVAVHRDDMITR"
     gene            3345..4397
                     /gene="phoE"
                     /locus_tag="OPY25_002895"
     CDS             3345..4397
                     /gene="phoE"
                     /locus_tag="OPY25_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HCS0928466.1"
                     /translation="MNKSTLAIVVSIIASASVHAAEVYNKNGNKLDVYGKVKAMHYMS
                     DYDSKDGDQSYVRFGFKGETQINDQLTGYGRWEAEFAGNKAESDSSQQKTRLAFAGLK
                     LKDIGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFG
                     IVDGLDLTLQYQGKNEDRDVKKQNGDGFGTSVSYDFGGSDFAVSGAYTLSDRTREQNL
                     QRRGTGDKAEAWATGVKYDANDIYIATFYSETRNMTPVSGGFANKTQNFEAVIQYQFD
                     FGLRPSLGYVLSKGKDIEGVGSEDLVNYIDVGAIYYFNKNMSAFVDYKINQLDSDNTL
                     GINDDDIVAIGLTYQF"
     gene            complement(4448..4849)
                     /gene="crl"
                     /locus_tag="OPY25_002896"
     CDS             complement(4448..4849)
                     /gene="crl"
                     /locus_tag="OPY25_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HCS0928467.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGQCEDNRFFFDCLAVCVNV
                     KPAPEKREFWGWWMELEAQEKRFTYRYQFGLFDKEGNWTVVPINETEVVERLEYTLRE
                     FHEKLRDLLISMELALEPSDDFNDEPVKLSA"
     gene            complement(4907..6151)
                     /gene="frsA"
                     /locus_tag="OPY25_002897"
     CDS             complement(4907..6151)
                     /gene="frsA"
                     /locus_tag="OPY25_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HCS0928468.1"
                     /translation="MTQANLSETLFKPRFKHTETSTLVRRFNRGSQPPMQSALDGKNV
                     PHWYRMINRLMWIWRGVDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     KQAMDWQQKACQEQDAMRSGRYWLHASTLYNIAAYPHLKGDELAEQAQALANRAYEEA
                     AQRLPGSLREMEFAVPGGSPVTAFLHMPKGDGPFPTVLMCGGLDAMQIDYYTLYERYF
                     APRGIAMLTLDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLEAPRLKAVACLGPVVHALLSDPQRQSTVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGFWKNDPFSPEEESRLITTSSSDGKLIEIPFN
                     PVYRNFDHALQEITDWINHRLC"
     gene            complement(6240..6698)
                     /gene="gpt"
                     /locus_tag="OPY25_002898"
     CDS             complement(6240..6698)
                     /gene="gpt"
                     /locus_tag="OPY25_002898"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCS0928469.1"
                     /translation="MSEKYVVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            6947..8404
                     /gene="pepD"
                     /locus_tag="OPY25_002899"
     CDS             6947..8404
                     /gene="pepD"
                     /locus_tag="OPY25_002899"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HCS0928470.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEHIVSWAKEKG
                     LYVDRDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNSDTVHDFTTDPIRPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADDNVVHGPLEVLLTMTEEAGMDGAFGLQSGWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLPLTREAVPAGFACFKLTLKGLKGGHSGG
                     EIHLGLGNANKLLARFLAGHAEELDLRLIDFNGGTLRNAIPREAFATLAVATDNVGAL
                     KTLVNAYQDILKNELAEKEKNLTLQLNEVASDKAALTAPSRDTFVRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMSDANVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGSYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPDMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKAIPAK"
     gene            complement(8559..9173)
                     /locus_tag="OPY25_002900"
     CDS             complement(8559..9173)
                     /locus_tag="OPY25_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HCS0928471.1"
                     /translation="MILLQLSSAQGPDECCLAVKKALDCLTKEAAREKVSLTRLETEP
                     GRLPDTLRSALVSLDGEKAMAFSERWCGTLLWICTSPYRPHHGRKNWYVGIGRFSADE
                     HIQSDEIRFETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWRLEQQRQNECAALKSERRLFHHQIERGNPLRIFKGMAFTPQ"
     gene            complement(9170..10309)
                     /locus_tag="OPY25_002901"
     CDS             complement(9170..10309)
                     /locus_tag="OPY25_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006895405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HCS0928472.1"
                     /translation="MGNYIRPLSDVVFSIASDNLWIEDSAIQQLYTTAKLTGMKRVIG
                     MPDLHPGRGYPIGAAFFSRGRFYPALVGNDIGCGMALWQTDILGRKYNADKLEKRLAS
                     LPDVADAQWLEENVPAVMQHHSWRSALGSIGGGNHFAELQQVDRIVDADSFALSGLQK
                     AQLLLLVHSGSRGLGQAILRRHVEAFSHNGLPEDSDDARHYLAEHDDALAFARSNRAL
                     IARRILQQLRAEGEPRLDVAHNFVEPCTVAGEAGWLHRKGATPDGQGLVIIPGSRGDY
                     SWLVKPVVSEESLFSLAHGAGRKWMRTECKDRLSAKFTPRQLCRTGMGSRVICRDRQL
                     IYEEAPQAYKSIDSVVDCLADAGLITPVACLRPVLTLKTSGEKSA"
     gene            complement(10528..11583)
                     /gene="dinB"
                     /locus_tag="OPY25_002902"
     CDS             complement(10528..11583)
                     /gene="dinB"
                     /locus_tag="OPY25_002902"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCS0928473.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARQFGVRSAMPTAMALKLCPHLTLLPGRFDAYKEASRHVRDIFSRYTSLIEPLSL
                     DEAWLDVTDSPHCYGSATLIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNG
                     QYVITPADVPDFLKTLPLAKIPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKF
                     GRVLWERSQGIDERDVNSERLRKSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAI
                     VKPDLLIARQGVKLKFNDFQQTTQEHVWPQLNKEDLITTARKTWDERRGERGVRLVGL
                     HVTLLDPQLERQLVLGL"
     gene            11833..12573
                     /locus_tag="OPY25_002903"
     CDS             11833..12573
                     /locus_tag="OPY25_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HCS0928474.1"
                     /translation="MRKIAFFLAMLLMPCVSFAGLLSSSSPVTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICNYSGGLGPKRRQGDFKSPEGFYSVQRNQ
                     LKPDSRFYKAINIGFPNAYDRAHGYDGKYLMIHGACVSVGCYAMTDSGIDEIFQFVTA
                     ALVFGQPSVQVSIYPFRMTDANMQRHKYSYYKDFWAQLKPGYDYFEQTHKPPTVSIVD
                     GRYVVSKPLSHEVVQPQLASNYTLSEAK"
     gene            complement(12544..13311)
                     /locus_tag="OPY25_002904"
     CDS             complement(12544..13311)
                     /locus_tag="OPY25_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HCS0928475.1"
                     /translation="MCELLGMSANVPMDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSYHSPIAKLVQNYPIKSCSVIAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLNGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMTAVFKYIA
                     TLATVLREKGVFNMLLSDGRYVMAFCSTHLHWITRRAPFGVATLVDQDMEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWALFCLGERII"
     gene            complement(13475..14053)
                     /gene="lpcA"
                     /locus_tag="OPY25_002905"
     CDS             complement(13475..14053)
                     /gene="lpcA"
                     /locus_tag="OPY25_002905"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HCS0928476.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYDYIFS
                     RYVEAVGREGDVLLGISTSGNSGNVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            14293..16737
                     /gene="fadE"
                     /locus_tag="OPY25_002906"
     CDS             14293..16737
                     /gene="fadE"
                     /locus_tag="OPY25_002906"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HCS0928477.1"
                     /translation="MMILSIIATVVLLGALFYHRVSLFLSSLILLAWTAALGVAGLWS
                     IWLLVPLAIILVPFNLTPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPQLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYVQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     EEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGVVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPDRLLGGEEELGITCALIPTSTPGVEIGRRHFPLNVP
                     FQNGPTRGNDIFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGESNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMAAAQNNDVNAFDKLLFKHIGHVGSNTVRSFWLGLTRGLTSHT
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISTRLGDVLSQLYLASAV
                     LKRYDDEGRHEADLPLVHWGVQDALYRAEQAMDDLLQNFPNRVVAGLLTAMIFPTGRH
                     YLAPSDKLDHAVAKILQVPNATRSRIGRGQYLTPAEHNPVGLLEEALRDVIAADPIHQ
                     RICKELGKNLPFTRLDELARNALAKGLIDKDEAAILAKAEESRLRSINVDDFEPEALA
                     TKPVKLPEKVRKVEAA"
     gene            16846..17613
                     /locus_tag="OPY25_002907"
     CDS             16846..17613
                     /locus_tag="OPY25_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCS0928478.1"
                     /translation="MSGLKITLLQQPLVWMDGLANLRHFDRQLELVSGRDVIVLPEMF
                     TTGFAMEAANNSLSQDSVITWMQAKARQTDALIAGSAALQTERGAVNRFLLVEPEGKV
                     HLYDKRHLFRMADEHQHYAAGDKRIIVQWRGWRILPLICYDLRFPIWSRNRNDYDLAL
                     YVANWPAPRSLHWQTLLTARAIENQAYVAGCNRVGTDGNGLHYRGDSRIINPQGDIIA
                     TAEPHQATRIDADLSLVALQDYREKFPAWRDADPFTL"
     gene            17923..18330
                     /locus_tag="OPY25_002908"
     CDS             17923..18330
                     /locus_tag="OPY25_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spy/CpxP family protein refolding chaperone"
                     /protein_id="HCS0928479.1"
                     /translation="MKNFVRTTLLAATLAGVSFGAFATAVPNPPLPAQDPIVQHLKLT
                     NDQITRIKKLHQQLETDVSQISMKGIKDGALIEVIKSGKWDDAAVKQQLAAFSNIEQQ
                     ARYYRVKYYFDLSKVLTPEQRQQVQQDLAQALE"
     gene            18655..19374
                     /gene="pagN"
                     /locus_tag="OPY25_002909"
     CDS             18655..19374
                     /gene="pagN"
                     /locus_tag="OPY25_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin/invasin protein PagN"
                     /protein_id="HCS0928480.1"
                     /translation="MKNFFAVCIIPLVVTWSATASAKEGIYITGKAGTSVVNVYGINS
                     TFSQEEIVNGHATLPDRTKGVFGGGVAIGYDFYDPFQLPVRLELDTTFRGETDAKGGQ
                     DIIAFGQPVHINVKNQVRMTTYIVNGYYDFHNSTAFTPYISAGVGLAHVKLSNNTIPV
                     GFGINETLSASKNNFAWGAGIGAKYAVTDNIMIDASYKYINAGKVSISKNHYAGDEHT
                     AYDADTKAASNDFMLGITYAF"
     gene            complement(19378..19566)
                     /locus_tag="OPY25_002910"
                     /pseudo
     CDS             complement(19378..19566)
                     /locus_tag="OPY25_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19602..19735
                     /locus_tag="OPY25_002911"
                     /pseudo
     CDS             19602..19735
                     /locus_tag="OPY25_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4999 a         5325 c         4953 g         4810 t
ORIGIN      
        1 tgattcaatt aatgagtaga acgtattatt attacgcatc atataaccac gaaaattatt
       61 ttcgatgccc gttgtcacag gcttggcagc ccctgaaata acagactccg tctctttatt
      121 gaaaagctgg tattgaatat ttgcgcagtt taaatcacag ggggaacatt taagatttaa
      181 aacaagcagt atcgtgttat tttcaaaaac aagggcataa tgattgctgg cagatgaaca
      241 taacgggaat aacgcgagaa gaagaattat tatcaatttc atattattat atagactccg
      301 tcaaagaaaa ctttcatttc acttgttctt ctgttaactc accctttcat ttcacgcccc
      361 tgagaatagc gaaaggcata ccatgcagaa tgaatgcttt ccgaactgac gtcctcacag
      421 acatccatac catgccaaac aagtacgcga gaaagaaaat gagaagattg ttatgaaaga
      481 aaagtttgta accgcttgat tgagatggtg ccgataatag gagtcgaacc tacgaccttc
      541 gcattacgaa tgcgctgctc taccaactga gctatatcgg ccctgagaag ggtgtgttca
      601 cgcgggtgaa tcacggggta gaaggttaaa actaaccggg cggtgcgtca atagccttgc
      661 tactcaaccg gctatttttg caccgctcgt cattaattac gcacgaatcg taccatcgcc
      721 aaagcctatc cacttatagg tggtaagcgc ttcaagcccc atcggaccgc gggcatgtaa
      781 tttctgcgtg ctgaccgcca cttctgcgcc aagcccaaac tgcccgccat cggtaaaacg
      841 ggtagaggcg ttgacataaa ccgcagcgga atctacttcg ttcacgaaac gcgcagcatt
      901 atgcatatcg cacgttaaaa tcgcatcgga gtgctgagtg ccatgttcgc gaatgtgggc
      961 gatagcgcca tccatatttt cgaccaccac aacgttcaga tccagagaca gaaactcgtt
     1021 atccagctct tccggtttca gcgccaccag tttggcaggg ccatgcagtg cctgcatgac
     1081 ggtttcatcc ccatgcaacg ttacgccact ctccgccatc tgcttgctca gcgcaggcaa
     1141 aaagcgttct gcgatgtcct gatgcaccag caaggtttcc accgtgttac aggtgctcgg
     1201 gcgctgggtt ttagcgttga cgataatctt cagcgctggg gcgatgtctg cgctgctatc
     1261 gacaaaaata tggcacacgc caatcccgcc ggtaatcacc ggaatggtgg attgctcgcg
     1321 gcagagttta tgcaagcctg cgccgccgcg cgggatcagc atatcgatgt acttatccat
     1381 acgcagcatt tcactgacca gcgaacgatc cggattatca atcgcctgaa ccgccgcttc
     1441 cggtaaatcg caagctttca gcgccttctg aatgacaaga acggttgcgg cattcgtgcg
     1501 atgcgtctct ttcccaccgc gtagaatcac cgcattaccg gttttcagac acaaagaagc
     1561 cacatcaacg gtaacattcg gacgcgcctc atagataacg ccaaccacgc ccaacggcac
     1621 gcggcggcgc tccagacgca ggccgctgtc cagcagaccg ccgtcgatca cctgcccggc
     1681 cgggtcggcg agattacaga cctggcgcac atcgtcagca atcgctttca gacgcgcagg
     1741 ggtcagcgcc aggcggtcca gcatcgcttc gctcaggcca ttggctcgcg cctgctcaac
     1801 atcttgtacg ttcgcgctga ggatactttc catttgcgct tccagttcat cggctatttt
     1861 ttccagcacg cgattttttt cgcagctgga gagcagcgcc agcttatacg acgccgcttt
     1921 agcagcaatg cccatttgtt ccagcatatg cctgttcctt atcgagtaat catgtcatca
     1981 cgatgaacag cgaccgggcc atattcatag cccagaatcg catcgatttg ttgagagtgg
     2041 tgaccggcta tccgccgcag agcatcactg ttataacggc tgacgccatg agcgatatca
     2101 cgcccttgca ggttacaaat tctgatgacc tccccccgcg aaaaattgcc cgtcacgctt
     2161 ttgatgcctt ttggcagaag tgaactgcca cgttccagca ttgccgcggt cgcgccttca
     2221 tcaaccgtaa tttcgcctgc cggcggcgcg ccgaagatcc aacgtttgcg gttctccagc
     2281 ggcgaggctt gcgcatgaaa acgggtgccg acggaaatcc cctccatcac atcgccgatc
     2341 acgcccggtt tactgcctga ggcaataatc gtatcaatac ccgcgcgaca ggccacgtct
     2401 gccgcctgaa gcttagtgct cataccaccg gttcccagcc cggaaacgct gtctcccgcg
     2461 atagagcgca gcgcatcgtc aacgccatac acatctttga taagctccgc ctgcggattg
     2521 ctacgcggat cggcggtaaa taatccttgc tgatcggtca gcagcagcag tttatccgcg
     2581 cctgccagga tcgccgccag cgcggagagg ttatcgttgt cgcccacttt aatttccgct
     2641 gtcgcaacgg catcattttc attgataacc ggcacaatat ggttatccag taacgcacgc
     2701 agcgtatcgc gggcgttcag aaagcgctct ctgtcttcca tatccgcacg cgtcaacagc
     2761 atctgcccga tatggatacc gtaaattgaa aacaactgct cccacagttg aatcagacgg
     2821 ctttgcccta ccgccgccag aagctgttta gaggcaattg ttgccggcag ttccgggtag
     2881 ccgagatgtt cacgtccggc ggcaatcgcg ccagaggtaa cgataacaat acgatgtccc
     2941 gcggcgtgta gctgcgcgca ctggcggaca agttctacga tatgggcacg gttcaggcgg
     3001 cgcgatccgc ctgttagcac gctggtgccg agttttacga ccagcgtctg gctgtcactc
     3061 atgattctct gccgttcaaa ataagaaata aagaccaaat gaacgtttta gcaggactgg
     3121 ctccggttgc caacaacctg tacgcgtagc gtgaaatttt gttgcgcagg atcagcaagc
     3181 gtagcggcgg aatttgacca ttttattacc gcaacaatta aatatatttt tttaaaaaaa
     3241 ctctcacttt gtcataaatc tttcattacc gaacgttaaa aaccttcctg ttttttaccg
     3301 ggtctcccga caaatcatag cgcgtaatta aaacaggaat ggaaatgaat aagagcactc
     3361 tggcaatagt ggtgagtatc atcgcatcag catctgttca cgccgccgag gtttacaata
     3421 aaaacggtaa taagcttgat gtgtatggaa aagttaaagc catgcactat atgagcgatt
     3481 atgacagcaa agatggcgat caaagctacg ttcgttttgg ttttaaaggc gaaacgcaaa
     3541 ttaacgatca attgaccggc tacgggcgct gggaagctga gtttgccggt aataaagccg
     3601 aaagtgattc gtcccagcaa aaaacccgcc tggcctttgc tggtctgaaa ttaaaagata
     3661 tcggttcttt tgactatgga cgtaacctgg gcgcgctgta cgatgttgag gcctggacgg
     3721 atatgtttcc cgaattcggc ggcgactctt ccgcccagac cgataatttt atgactaaac
     3781 gcgccagcgg gctggcgact taccgcaata ccgatttctt cggcatcgtt gatggactgg
     3841 atcttacctt acagtatcag gggaaaaacg aagatcgcga tgtgaaaaag caaaacggcg
     3901 acggcttcgg cacttccgtg agctatgatt tcggcggcag tgattttgcc gtcagcggcg
     3961 cttatactct ctccgatcgc accagggagc aaaatctgca gcgccgcggt acgggcgata
     4021 aagccgaagc ctgggctacg ggtgttaagt atgacgcgaa tgatatttat attgcgactt
     4081 tctattcaga aacccgcaac atgacgccag tttccggcgg atttgccaat aaaactcaaa
     4141 acttcgaagc ggttatccag tatcagtttg actttggtct gcgtccgtca ttaggctatg
     4201 tgctgtcaaa aggcaaagat attgagggcg tcggcagtga ggatttggtg aattacattg
     4261 acgttggcgc aatctattat ttcaacaaaa atatgtccgc gtttgtagat tacaaaatca
     4321 atcagcttga tagcgataac acgttaggca ttaatgacga tgatattgtg gcaatagggt
     4381 tgacctacca gttctgataa gtcgcattgt gcctgatggc gctacgccat caggcatggc
     4441 agcagggtta tgccgacagt tttaccggct cgtcgttgaa atcgtcagac ggctccagcg
     4501 ccagctccat agaaatcagc aggtcgcgta gcttttcatg aaactcgcgt agcgtgtatt
     4561 ccagtcgctc caccacttcg gtttcgttaa tcggcactac ggtccagttg ccctctttat
     4621 caaacaaacc aaactgataa cgataagtga agcgtttctc ttgtgcttcc agctccatcc
     4681 accagcccca aaattcacgc ttctctggcg cgggcttcac gttgacgcaa actgccaggc
     4741 aatcgaaaaa aaaacgattg tcttcgcact gcccttcccg gatatagggg ccaagcgcgg
     4801 taaatttctt gatcaatcta cttttcgggt gtccactcgg taacgtcatt gcgatctcct
     4861 ttaatgaagc aactgtttta ccaaatcaat agaatttatc aatctattaa cacaatctat
     4921 gattaatcca gtcggtaatt tcttgcagcg cgtggtcaaa attgcggtac accgggttaa
     4981 aagggatctc tatcagctta ccgtctgaag atgatgttgt aattaagcga gactcttctt
     5041 ccgggctgaa aggatcgttt ttccagaagc cggaaagcat tggcgtagga caacgtctgc
     5101 ccagtagccc ctgtactttc aacgaatagc ggttgagctc cacacgcagc gcctcatccg
     5161 aagcatcatg catacccaga cggctggcca gcacatccag atacatctcc ggcactgtgc
     5221 tctgtcgttg cggatcgcta agtagcgcat ggaccaccgg ccccaggcaa gccaccgctt
     5281 tcaaacgcgg cgcttccaga taggccagac gcaccgcaac gttggcgcca aaacggaaac
     5341 caaacgccgc aacacgggta tgatccaccc aggggacatt aggaagcgct tttaacacat
     5401 gctggtggag caagctggaa tcctgggtta atttccactt tgatgaaaat ccaaccgaag
     5461 gcatatcaag cgttaacatc gcgataccgc gcggcgcgaa atagcgttca tacagggtgt
     5521 aatagtcgat ttgcatggcg tccaggccgc cgcacatgag caccgtcgga aacggaccat
     5581 cccctttcgg catatgtaaa aacgcggtga caggcgaacc gccaggaacg gcaaattcca
     5641 tttcacgtaa cgagcctggc aaccgctgcg cggcctcttc ataggcgcga ttcgccagcg
     5701 cctgcgcctg ctccgccagc tcatcgccct tcaaatgcgg gtaggcggca atgttataga
     5761 gcgttgaggc atgaagccag tagcgtccgc tgcgcatggc gtcctgttcc tgacaggctt
     5821 tctgctgcca gtccatcgcc tgctttgccc actcataaat ccagttgccg ccgcggtaac
     5881 cgatgaccgt atcgtataaa tcatcatccg ttcgctctgc gtcgctcatc acaatgcgcg
     5941 cctgcacatc aaggatttct cgtgggtcaa cgccgcgcca aatccacatc aggcggttta
     6001 tcatgcgata ccaatgcggg acgttcttac cgtccagcgc ggattgcatg ggcggctgcg
     6061 acccacgatt gaaccgacgg acaagggtag acgtttcagt atgtttaaag cggggtttga
     6121 acagggtttc gctgaggtta gcctgtgtca ttcgtgcagc ctccttggat actcatagag
     6181 gcttattgta accaataaaa cagcgcccgg cattgccggg cgctctgaaa agctgctgat
     6241 taacgacctg aaatcggcgg tacaaatacc acacccatat cccagggctg ctcaatccag
     6301 gtgttctgag gaatatcaat aacataatca tcaaccagcg gacggcccgc cggtttagcg
     6361 aaaatcgtga cgaaatgcgc tttagggtac atttcgcgaa tcgcgacggc ggtgccgccg
     6421 gtatcgacca gatcgtcgat gacgataaag ccttcgccat cgccttctgc acgtttcagc
     6481 actttcagtt cgcgctggtt atcgtgatcg tagctggaga tgcatacggt atcgacatga
     6541 cgaatgccca attcacgcgc cagtagtgcg cccggtacaa ggccgccacg acttacggca
     6601 ataatgcctt tccattgttc tgaaggcatg aggcggctcg ccagtttgcg tgcgtgaatc
     6661 tgcaacatgt cccaggtgac gacgtatttt tcgctcatgt gaagtgtccc agcctgttta
     6721 tctacggctt aaaaagtgtt cgagggggaa atagttgcgc gagattatag agacctgacg
     6781 cgctaaaaac cagtgtttag cggaatccac gcctcttttt gtatgcttta tactacccgc
     6841 aggcggagaa agtggtattc tcagtcgcat ctcgtaagag ttattaattc cgctaaccct
     6901 gtggcctgta agaacgtttt tcagaccacc gccaaggaga cttatcgtgt ctgaactgtc
     6961 tcagttatca ccacaacctt tgtgggatat ttttgccaaa atctgttcta ttcctcaccc
     7021 gtcctatcac gaagagcaac tcgcggaaca tattgtgagt tgggccaaag agaaaggcct
     7081 ttacgtggat cgcgaccagg tcggtaatat tctgatccgt aagcccgcca ctgcaggtat
     7141 ggaaaatcgc aagccggtcg ttttacaggc gcatctggat atggtgccgc aaaaaaatag
     7201 cgacaccgtt cacgacttca ctacagatcc catccggcct tatattgatg gcgaatgggt
     7261 taaagcgcgc ggtactacgc tcggcgccga caatggtatt ggaatggctt ctgcgttagc
     7321 ggtactggct gacgataatg tcgtccatgg cccgctggaa gtgctgctga ctatgaccga
     7381 agaagcgggc atggatggcg cgttcggcct ccagtccggc tggttgcagg ctgacatcct
     7441 gatcaacacc gactctgaag aagaaggtga gatctatatg ggctgcgcag gcggcatcga
     7501 ttttacctct aatctgccgt tgacccgtga agctgtaccc gcaggatttg catgctttaa
     7561 gctaaccctg aaaggtctga aaggcggcca ctccggtggt gaaattcacc tcggccttgg
     7621 caatgccaac aaattgctgg cgcgttttct ggccgggcac gcagaagaac tggatctgcg
     7681 tctgatcgat ttcaacggcg gcacgctgcg taacgcgatt ccgcgcgaag cgttcgctac
     7741 cctcgccgtt gccacagaca acgtaggcgc tctgaaaaca ttagtgaacg cttaccagga
     7801 tattctgaaa aacgaactgg cggaaaaaga gaaaaacctg acgctgcaac tcaatgaggt
     7861 tgccagtgat aaagccgcat tgaccgcgcc gtcacgcgat acctttgtgc gcctgctgaa
     7921 cgcaacgccg aacggcgtga tccgcaattc agacgtggcg aaaggcgtag tggaaacatc
     7981 gctgaacgtt ggcgtggtca caatgtctga tgcgaatgtc gaaattcact gcctgattcg
     8041 ctctcttatc gacagcggta aagattatgt ggtgagtatg ctggattcgc tgggcaagct
     8101 ggctggcgcg aaaaccgaag caaaaggcag ctatccgggc tggcagcccg atgcgaactc
     8161 gccggtcatg cacctggtgc gggaaaccta tcagcgtctg ttcaacaaga caccgaacat
     8221 ccagattatc cacgccggcc tggaatgcgg tctgtttaag aaaccctatc cggatatgga
     8281 catggtttct attgggccta ccattaccgg acctcactct ccggatgagc aggtacatat
     8341 cgaaagcgtg ggccactact ggactctgct gaccgaattg ctgaaagcga ttcctgcgaa
     8401 gtaagaaagc gctaaaatgc ccgtctcatt tctggacggg ctatcaatat ggaatatcgg
     8461 gtatccattg ccagataagc tctcctggat gcgctgaata gcgctgcggc tacacgcgaa
     8521 tagccagaca gccctataac agcgctggta gcaccgaatt attgtggcgt aaacgccatt
     8581 cctttaaata tccgtagcgg attgccgcgc tcaatctgat gatggaacag acgcctttca
     8641 gacttcaacg ccgcacactc attttgccgt tgctgttcca gccgccaggc aatcagcagc
     8701 cgggccagac gcttattcgc atgttgactg cgctccgact gaaccttcac gctaatcccg
     8761 ctcgccaggt gcgtggcccg cactgccgag tcggttttat taacgtgctg cccacccggg
     8821 ccggaagagc gcagagtctc gaaacgaatc tcatcagact gtatgtgctc gtcggcggaa
     8881 aagcgcccaa tgccgacgta ccagtttttt cgcccatggt gcgggcgata cgggctggta
     8941 caaatccaca gtaacgtgcc gcaccaacgt tcactgaaag ccatggcttt ttcgccgtcc
     9001 agcgagacca gcgcagaacg cagcgtgtct ggtaatcgtc ccggctctgt ttcaagccgt
     9061 gtcagcgata ccttttctct ggcggcttct ttcgtcagac aatccagcgc tttttttacc
     9121 gccagacaac actcgtccgg tccctgcgca gaagaaagtt gcagtaagat catgcgcttt
     9181 tctcccctga ggttttcagc gtcagcaccg gacgcaggca ggcaactggc gtaatcagtc
     9241 cggcgtctgc cagacaatcc acaacgctat cgatggattt atacgcctgc ggcgcttctt
     9301 cataaatgag ctggcgatcg cggcaaatca cccggctacc catcccagta cggcagagct
     9361 gtcgcggggt aaattttgcc gataaccggt ctttacactc ggtacgcatc catttgcgcc
     9421 ccgcgccgtg cgccagggag aagaggctct cctcgctgac gacgggtttc accagccagc
     9481 tataatcgcc gcgcgagccg gggataatca ccagtccctg cccatctggc gtagcgcctt
     9541 tacggtgcag ccaccccgcc tcacccgcga cagtacaggg ttcaacgaag ttatgcgcca
     9601 catccagccg cggttcgccc tcagccctga gctgttgcag tatccggcgg gcaatcagcg
     9661 cgcgattact gcgggcaaat gccagcgcat cgtcatgttc tgcaaggtag tggcgcgcat
     9721 cgtcgctatc ttccggcaaa ccgttatgcg aaaacgcctc cacatgacga cgcaggatag
     9781 cttgccccag accgcgtgaa ccactgtgta ccagcagtaa taactgcgct ttttgcaacc
     9841 ccgacaaagc gaacgaatca gcatcgacga tgcgatcgac ctgctgcagc tcggcaaaat
     9901 gattgccgcc gccaatggaa cccagcgcag agcgccacga atgatgctgc attacggcgg
     9961 ggacattctc ctccagccac tgcgcgtccg ccacgtcagg cagcgacgcc agccgcttct
    10021 ccagtttatc ggcgttatat ttacgcccta aaatatccgt ttgccataac gccatgccgc
    10081 agccgatatc gttgccgacc agcgccggat aaaaacgtcc acgcgagaaa aaggctgcgc
    10141 caataggata gccgcgcccc ggatgcagat ctggcatccc gataacgcgt ttcataccgg
    10201 ttaacttagc cgtcgtatat aattgttgga tcgcggaatc ttcgatccac aggttatccg
    10261 atgcgataga aaataccaca tctgataaag gacgaatata attgcccata taccattcca
    10321 tatatgaatt aaaaaatcag gaaatggcag actaatccag ggcaataaaa gaaaattaat
    10381 cctggaaagg tctgcaaagt gcgttcagag aataaagtgt catgatgaac ctcctttgca
    10441 gttattgaga atgagaaaac gcgggtatag taatactgaa atttagatgg cgcaatcgta
    10501 atagtgataa aatcttaata gcctgactta taaccctaac accaactgtc gttccaactg
    10561 agggtcgagc agcgttacgt gtagccccac caaccgtacg ccgcgctcgc cgcgacgctc
    10621 gtcccaggtt ttacgggcgg tggtaattaa gtcttcttta tttaattgcg gccagacatg
    10681 ttcctgagtg gtttgctgaa aatcattaaa ttttaattta acgccctgtc gggcaatcag
    10741 taaatcgggc tttactatag ccagacgacg ctccagttcc ggatataaat gttcaataat
    10801 ggcctcgcag tccgaccatt catgaatatc ctccgccaga gtacgctcaa cgcctaccga
    10861 tttacgcagc ctttcgctgt taacatcacg ctcgtcaata ccctgactac gctcccataa
    10921 tacccggcca aatttaccaa agcgtttgag aagcatcgcc agatcgcact gttgaatatc
    10981 cccgcaggtt cttaacccca tattttccag tttggcggcg gaaactttcc ccacgcctgg
    11041 aattttggct aacggcaacg ttttaagaaa gtcgggtaca tcggctggcg taataacata
    11101 ttgtccgttc ggtttattga gatcggaggc gatcttcgcc agaaatttca ctggcgcaac
    11161 gccggcggag gcggtgagtt gcagttcatt gaaaatagtc tgacgaatct ccctggcgat
    11221 cagagttgcc gaaccataac agtgcgggct gtcagtcaca tccagccagg cttcatccag
    11281 cgagagcggt tcaatcagtg aagtgtagcg ggaaaagatg tcacgtacat gccgcgaagc
    11341 ctctttatag gcgtcaaagc ggccaggcag taaggtgaga tgggggcaca gctttagcgc
    11401 catggcagtc ggcatcgcgc tgcgtacgcc aaactggcgc gcaggatagt tggcggtact
    11461 gataacgcct cttcgctcac gactcccgcc aatggcaatg gggatatcgc gtaacgccgg
    11521 attatcacgc atctctaccg cggcaaaaaa acagtccata tcaacatgta tgattttgcg
    11581 catcgctcgc ccccacaata ctgtttaagt gtacagtatg ttttattgcg cgcaaagaga
    11641 cattcgcgtt aaaaatgcga catattcgaa ggtatgacga cgaaagcggc gggaaaattg
    11701 taaacgtaca cacggggact tgcgaaaaac tgccgtggtg ctaatgtgag cgctccaaat
    11761 ccagattact ccgatttggg gactcttttg ccgttctggc gtgtgtaacc gttttatcaa
    11821 ggaacaagca gtatgcgtaa aatcgcattt tttcttgcga tgcttctgat gccgtgcgtc
    11881 tcatttgccg gtttgctgag cagcagcagc cccgtcacgc cggtcagtaa agagtataag
    11941 cagcagttaa tgggctcacc ggtctatatt caaattttta aagaagagcg cacccttgat
    12001 ctctacgtca aaatgggtga gcaataccag ttgcttgata gctacaaaat ttgcaactat
    12061 tccggcgggt taggcccgaa acgccgtcag ggcgatttta aaagtccgga agggttttac
    12121 agcgttcagc gtaatcaact caagccagac agccgttttt ataaggccat caacattggt
    12181 tttcccaatg cctacgatcg cgcgcatggc tatgatggta aatatctgat gattcacggt
    12241 gcctgtgttt ccgtcggctg ctatgccatg accgacagcg gcattgatga gattttccag
    12301 tttgtcaccg ccgcgctggt ctttggtcag ccaagcgtac aggtgagtat ttatccgttc
    12361 cggatgaccg acgccaatat gcagcgtcat aaatattcat attacaaaga tttctgggcg
    12421 cagctaaaac ccggctacga ttattttgaa cagacgcata agccgccaac tgtttctatc
    12481 gttgatggac gttacgtcgt gagcaaaccg ttgagtcacg aagtcgttca gccacagctg
    12541 gcctcaaatt atacgctctc cgaggcaaaa taacgcccat tcgcctggca taatcttttg
    12601 ccaggtttca ttccccgtta gcggctgggt agcaatcacg gtaaccacgt catttggcgt
    12661 ggtctgtgaa ctgaaatcaa tttccatatc ctgatccacc agcgtggcta cgccaaacgg
    12721 cgcccggcga gtgatccagt gcaaatgggt tgagcaaaac gccatcacat atcgcccatc
    12781 tgacagcagc atgttaaaaa cgcctttttc acgtaatacc gtcgccagtg tcgcaatata
    12841 tttaaatacc gctgtcatgt tgcccggcgt gcggggataa cgctgcgtta atttatgcaa
    12901 tagccagcaa aacgcttttt cgctgtcggt ttcccccacc ggacgaaaat taccggtttc
    12961 cagcgactta taaccgttga gctgaccgtt atgagcataa gtccagttgc gtccccataa
    13021 ttcccgggta aaagggtgtg tattttccag cgctacttca ccgcgattag cctgacggat
    13081 atgagcgata accgagcagg acttgatcgg gtaattctgt accagtttcg caatcggcga
    13141 atggtagctc ggttgcggat ctttaaacgt gcgacagccc tttccttcgt aaaaggtaat
    13201 tccccagccg tctttatgcg gcccggttcc gccgccacgc tgcaccagtc cggtgaagct
    13261 aaagcagata tccatcggca cattggcgct catcccaagc agttcgcaca tacatcacct
    13321 accttaaaac ggttaattgc ctgataagac cagcaaagca cagctcgtag gccggataag
    13381 acgcttgcgt cgccatccgg cacaatgccc gatggcgctt cgcttatcgg gcctactcgt
    13441 tccaggcccg ataagaccgg caaaaattat cggcttattt aaccatctct ttttcgatca
    13501 actgaatcag gatatgaatc actttgatat gaatttcctg aatacgatcg gcataaccga
    13561 agtgcggtac gcgaatttca atatccgccg ttcccgccat tttgccgccg tctttgccgg
    13621 tcaacgtaat cactttcatg cctttttcac gggccgcggc aatcgcttta atcacgttac
    13681 cagagttacc cgacgtcgag atccctaaca ggacatcgcc ttcgcgccct accgcctcaa
    13741 cgtaacgaga gaaaatatag tcatagccaa aatcattact gacgcaggat atatggctaa
    13801 catcagaaat cgcaattgcc gggtagcccg gacgattttc acgataacga cctgtcagct
    13861 cttcagcaaa gtgcatcgca tcgcaatggg agccgccgtt accgcaggaa agtaccttac
    13921 cacccgcttt aaaactgtca gccaacagga ccgccgcgcg ctgaatggcg tgaatattgg
    13981 cgtcatcttt taaaaaatta gccagcgttt ccgccgcttc gttcagttcg ttacgaataa
    14041 gatcctggta catgaggata tccttcagca tgaatgtaaa tgacagtatg cagtgtaccg
    14101 gatagcagta caggcgagaa gcataagccg aattaacgcc tcacgctttt gatttttcgt
    14161 gcccccaaaa acggcaacaa tgtgagcttt gttgtaatta ttttgtaaac acattgctaa
    14221 aagattttac atccactaca acctaatcat cacaagtggt cagacctcct acaagcaagg
    14281 gagcttttcg ttatgatgat tttgagtatt atcgctacgg ttgttctgct cggcgcattg
    14341 ttctatcacc gcgtgagttt atttctcagc agcctgattc tgctcgcctg gaccgccgca
    14401 cttggcgtcg ctggcctgtg gtccatctgg ctgttggttc ctctggccat tatcctcgtg
    14461 ccgtttaacc tcacaccgat gcgaaaatca atgatttccg caccggtgtt ccgcggcttc
    14521 cgtaaggtca tgccgccgat gtcgcgcact gagaaagaag cgattgatgc cggtacaacc
    14581 tggtgggaag gcgatctgtt ccagggcaag cctgactgga aaaaactgca caactatccg
    14641 caaccgcaac tcactgccga agagcaagcg tttctcgacg gcccggtaga agaagcgtgc
    14701 cggatggcga acgatttcca gattacccat gaactggcgg atctgccgcc ggaactgtgg
    14761 gcttacctga aagagcatcg tttttttgcg atgatcatta aaaaagagta cggcgggctg
    14821 gagttctccg cttatgtgca gtcccgtgta ctgcaaaaac tgtccggcgt ctccgggatt
    14881 ctggctatca ccgtcggcgt tccaaactca ctcggccctg gcgagctgtt gcagcactat
    14941 ggtacggaag agcagaagaa tcactatctg ccgcgactgg cgcgcggcca agaaatcccc
    15001 tgctttgcgc tgaccagccc ggaagcaggt tctgatgcag gcgctattcc ggataccggc
    15061 gtggtttgca tgggcgaatg gcagggccag caggtgctgg gtatgcgtct gacctggaac
    15121 aagcgttaca ttacgctggc gccgatagct accgtgttgg gcttggcgtt taagctttcc
    15181 gatccggata gattgttagg cggagaagaa gagctgggta ttacctgcgc cctgatcccc
    15241 acctcaacgc cgggtgtgga aattggtcgt cgtcacttcc cgcttaacgt tccgttccag
    15301 aatggcccaa cccgcggtaa cgatattttc gtgcctattg attatattat cggcggcccc
    15361 aaaatggccg gacagggctg gcgtatgctg gtggaatgtt tgtcggtagg acgcggtatt
    15421 accctgccgt ccaactccac tggcggggtg aaatccgtcg cgctggcaac cggcgcctat
    15481 gctcacattc gtcgtcagtt caaaatttct atcggcaaga tggaaggtat tgaagaaccg
    15541 ctggcgcgta ttgcaggtaa cgcttatgtg atggatgccg ccgcatcgtt aatcacctac
    15601 ggcattatgc taggcgaaaa accggcggta ctgtcggcta tcgtgaagta ccactgcacc
    15661 caccgcggcc agcagtccat tatcgacgcg atggatatca ctgggggtaa aggcattatg
    15721 ctgggcgaga gcaacttcct ggcgcgtgct taccagggcg cgcctatcgc gatcaccgtg
    15781 gaaggcgcga atatcctgac ccgtagcatg atgatctttg gtcagggcgc cattcgctgc
    15841 catccttatg tactggaaga gatggccgca gcgcagaata atgatgtgaa tgcctttgat
    15901 aaactgttgt ttaaacatat tggccatgtc ggcagcaata ccgtccgcag tttctggctt
    15961 ggcctgaccc gcggattaac gagccatacg ccaaccggcg acgccacgaa gcgttattac
    16021 cagcatctga accgactgag cgcaaacctg gccctgctgt ccgacgtgtc aatggcggta
    16081 ctgggcggca gcctgaaacg ccgcgagcgt atctccacgc gtctgggcga tgtgttgagt
    16141 cagctttatc tggcctcagc cgtactgaag cgttacgacg acgaaggccg ccacgaagcc
    16201 gacctgccgc tggtgcactg gggcgtacag gatgcgctgt atcgtgctga acaagcgatg
    16261 gacgatctgc tgcagaactt cccgaaccgc gtcgtggccg gattgctcac cgcgatgatc
    16321 ttcccgactg gccgtcatta tctggcgccg tctgataagc tggatcacgc cgtggcgaag
    16381 atcctacagg tgccgaacgc cacacgttca cgtattgggc gcggtcagta tctgacgccc
    16441 gccgaacata atccggtcgg tttactggaa gaagcgctgc gtgatgtcat cgctgccgac
    16501 cctatccacc agcgcatctg caaagaactg ggtaaaaatc tgccgtttac tcgtctggat
    16561 gaactggcgc gcaatgcgct ggcgaaaggg cttatagata aagatgaagc cgccatcctg
    16621 gcgaaagcgg aagagagccg cctgcgcagt atcaacgttg atgattttga acctgaagcg
    16681 ctggcgacca aaccggtaaa gctgccggag aaagtgcgta aagtcgaagc cgcataatca
    16741 gtctcgtgtc tttcctgccc cgctttcgcg gggctttttc ttgccgcttt tttattattg
    16801 ctcatgctac agtgtaaaga cgctgttcaa tgaggagctc cgatcgtgtc tggtttgaaa
    16861 attactctgt tgcaacaacc tttagtctgg atggacggcc tggcaaacct gcgtcatttt
    16921 gacagacagc tagagctcgt atctggccgg gatgtgattg ttctgcctga aatgtttacc
    16981 accggcttcg cgatggaggc cgctaataac tcactttcgc aagatagcgt gattacgtgg
    17041 atgcaggcca aagcccgaca aactgacgct ctgattgccg gcagcgcggc gctacaaact
    17101 gagcgcggcg ccgtaaatcg cttcttactg gttgaaccgg aaggcaaagt tcatctctat
    17161 gataagcgcc atctgtttcg tatggcggat gaacatcaac attatgccgc aggcgataaa
    17221 cgcatcatcg tgcagtggcg cggttggcgc atcctgccgt tgatctgtta cgatctgcgc
    17281 tttccgatat ggtcgcgcaa ccgcaatgat tacgatctgg cgctgtatgt agcgaactgg
    17341 cccgcgccgc gctcgctaca ctggcaaaca ttactgacgg cgcgcgctat tgaaaatcag
    17401 gcttatgtcg caggctgcaa ccgggttggc accgatggca acgggttaca ttatcgcggc
    17461 gatagccgaa tcattaatcc ccagggcgac attatcgcca ccgccgaacc acaccaggcg
    17521 acacgtatcg atgcagatct ttctctcgtc gccttgcagg actatcgcga aaaatttcca
    17581 gcctggcgcg atgccgatcc attcaccttg taagcaacct gccgctcacc gcggcgggat
    17641 tgtttcactc cgtaactctc cgtaaaacaa attcgcgtgg cgtaatgtgg caggcaacgt
    17701 attctgacta agagcctatc ccaccaggcg ttattggcgc agtcagtttg gacacggaca
    17761 gcgcgcaaaa accggagcgt acacgtagta cgtgaggatt ttgagcactg cccaggtcca
    17821 aaatggcaag taaaatagcc ctaatgggat aggctctaag ataattgctc gccattcgtg
    17881 ggtaataaaa acggttaatc actcccttat caggatatct tcatgaaaaa ctttgtacgc
    17941 acaactttac tggcagcgac tctggcgggc gtttcttttg gcgctttcgc caccgctgtt
    18001 cccaatcctc ccctgcccgc ccaggatcct attgtccagc atctgaagct gacaaacgat
    18061 cagattaccc ggatcaaaaa acttcaccaa caactggaaa ccgacgtcag tcagatttct
    18121 atgaagggaa ttaaagacgg tgcgctgata gaggtgatta aatccggtaa atgggatgac
    18181 gccgccgtaa aacagcagct tgcagccttc agtaacatag aacaacaggc tcgctattat
    18241 cgggttaaat attattttga tttaagcaaa gtcttaacac cagaacagcg tcaacaggta
    18301 caacaagatc tcgcccaagc acttgagtaa atatttttgc ccgttattcc tggataacgg
    18361 gctttatcca ggtcgggtac aaattcatct ttttcttaca gcatcgcacc atctcacact
    18421 acccgttaca caacgtagaa gtgaaaccgt acgtggggca atttggcgag gagatggatt
    18481 tccataccga cgattatcgt attgttattt aaaatcttca tctcattttt tacccgctta
    18541 cagaaaaccc agcgttacaa tagaccgttt tttgggcttc gtttatgtaa tcgttatatc
    18601 acaccctata ccgtgaaact tgtcttttag cccaatatta aggcaggttc tgaaatgaaa
    18661 aactttttcg cagtctgcat cattcccctt gtggtaacct ggtccgctac tgcatcagca
    18721 aaagaaggga tctatatcac cgggaaagcg gggacatccg tagtcaatgt ctatggaatc
    18781 aactcaacct tcagccagga ggagatagtc aatggtcatg caacgttacc tgaccgtacc
    18841 aaaggcgttt ttggcggcgg ggttgctatc ggttatgact tttatgatcc attccagctt
    18901 ccagtacgtt tagaactgga taccactttc agaggtgaga cggatgctaa aggcgggcag
    18961 gatattattg catttggtca gccagtacac ataaatgtaa aaaatcaggt ccgaatgacc
    19021 acttacatag ttaatggtta ttatgatttt cacaatagta cggcatttac accctatatc
    19081 agcgcaggcg ttggcctcgc tcatgtgaag ctaagtaata acaccattcc tgttggtttt
    19141 ggtattaatg aaactctgtc tgcttcaaaa aataactttg cctggggcgc aggtatcggt
    19201 gcaaaatatg ctgtaacaga taatattatg attgacgcca gttataaata cattaatgca
    19261 ggcaaagtga gcatttcaaa aaatcactat gctggtgatg aacataccgc ttatgatgca
    19321 gacacaaagg ctgcctccaa tgacttcatg ctcggcatta cttacgcctt ttaaacacta
    19381 tcggtaaaat agctggtcct gtgggttccc gaaggcgcaa tggaggatat cagtaatgaa
    19441 tactcctgcg ccttcagaaa atcgttgaac aggtgcaacc tggcgccatt tttcagtaca
    19501 ctgcaacgtt tctggtatgg gcttaacttc cggctaccca aaaacagtcc cgtcctgttg
    19561 tatgatctct aaatgtgaat ggcacgatta tgcgagatac ttacaagtgt ctggtatgaa
    19621 gatatactgc gaacgccgat gtaaacggcg cgcgtaacat tttagagcgg gacacgccgt
    19681 gcttgcctgt ggaaggagcg tgcagtcagg cagcccgttg gagcaggaac ccacgccctt
    19741 caggacgtgg aggatgtcaa tgcacaagaa ttggggaatc tttagcagaa tttattatct
    19801 ctacagtagc atctctcttg ttcccgtcat aaataaccca atgcctccag atctgaaacc
    19861 gccttcagca tgagcactgg ctgcaaataa caccaaataa aataataata taacaactac
    19921 cgagacaaaa aacacctctc taaagtattt agaattcata cagtcagctc atttaaattt
    19981 aacgtcacat gcaaccatgc atgcgtaaaa caagaaccac actcatatta ataatgatta
    20041 gtaatgtgag tgtgcgtata acgagataca gatgtatatt ccttaat
//
LOCUS       DAJVKX010000079        20035 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000079 DAJVKX010000000
VERSION     DAJVKX010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20035
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.079"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            232..3975
                     /locus_tag="OPY25_002912"
     CDS             232..3975
                     /locus_tag="OPY25_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HCS0928481.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLETNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDMPNHEPRGCPRGASYSWY
                     LYSANRLKYPLMRKRLMKMWREAKKLHRDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTVKTYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPRQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDSLGQENNPEWKTVAINSNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGTTGAETELQLSLLGSQDEIADVGFPYFGGEGSEYFNHVALDN
                     VLLHKLPAKRLQLADGSSALVTTVYDLTMANYGLERGLNDENCAASYDDTKAYTPAWA
                     EQITGVPRAQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLVFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYSGHLIDFNVRAERMGWLPSAPQLGTNPLYIAREAEKAGMTPVD
                     YTVKSLKDGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEYMLKYLLGTEHGIQ
                     GLDLGKQGGVKPEEVEWRDNGLDGKLDLVVTLDFRLSSTCLYSDIVLPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWESKSDWEIYKGIAKKFSEVCVGHLGKETDVVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMTVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKADGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLATNKEEEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKAVMGRKSNGNPEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLSRGGPIVWMSETDAKELGIEDNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAQ
                     LAYGFNYYGTVGSNRDEFVVVRKMKNINWLDGEGNDQVQESVK"
     gene            3972..5507
                     /gene="narH"
                     /locus_tag="OPY25_002913"
     CDS             3972..5507
                     /gene="narH"
                     /locus_tag="OPY25_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HCS0928482.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGMEYAWFNNV
                     ESKPGVGFPNDWENQEKWKGGWIRKINGKLQPRMGNRALLLGKIFANPHLPGIDDYYE
                     PFDYDYQNLHTAPESKHQPIARPRSLITGQRMDKITSGPNWEEILGGEFEKRAKDQNF
                     ENMQKAMYGQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYDA
                     DAIESAASTENEKDLYQRQLDVFLDPNDPAVIEQALKDGVPQSVIDAAQQSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVDSLRIPVQYLANL
                     LTAGDTQPVLLALKRMLAMRHYKRAETVDGKVDTRALEEVGLSEAQAQEMYRYLAIAN
                     YEDRFVVPSSHRELARDAFPEKSGCGFTFGDGCHGSDTKFNLFNSRRIDAVDVTSKTE
                     PHA"
     gene            5504..6214
                     /gene="narJ"
                     /locus_tag="OPY25_002914"
     CDS             5504..6214
                     /gene="narJ"
                     /locus_tag="OPY25_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HCS0928483.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQELFDALASSENLDKEDAQTLG
                     VFLRDLTAQDMLDVQAAYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLMAQYEQHG
                     LQLDSRELPDHLPLYLEYLAQLPKSEALGGVQDIAPILALLSARLQQRDSRYAVLFDL
                     LLKLANTVIDSGKVAEKIANEARDDTPQALDAVWEEEQVKFFADQGCGESEISAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            6214..6891
                     /gene="narI"
                     /locus_tag="OPY25_002915"
     CDS             6214..6891
                     /gene="narI"
                     /locus_tag="OPY25_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HCS0928484.1"
                     /translation="MHFLNMFFFDIYPYIAGSVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFAGHFLGMLTPHWMYEAFLPVDVKQKMAMIAGGACGMLTL
                     VGGILLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASAHLDGVAFIFRMHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QIVRARH"
     gene            7133..8662
                     /locus_tag="OPY25_002916"
     CDS             7133..8662
                     /locus_tag="OPY25_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HCS0928485.1"
                     /translation="MRFSSIFKIIILNIFISKMAHAAVCEERYPPDSEECQYVQELEQ
                     KAEQGDEGAQFSLGSWYAEGRYVKPDYKLAIKWLEKAGKQGSDFSYFILGYHYNYGEN
                     FPLSRQKALEWYRKAAELGDSSTQEILGDAYMYGDGFPQNTQLALEWYRKAASPTNDA
                     GVVRGQGSASSAQFKLGVMYAHGQGVPQDYQQTAILMRKAAENMYYPAQLYLGVAYFY
                     GEGVPQDYRQAVYWLNEGIPGSYTPGHIPLNALYDKAHPADQVHSQTWYRKTAQRVMA
                     KVQFNFGVWYYNGYHLLKDHNLALEWYRRAAAQGLAEAQDAIGVMFMQGEAVSQDYQQ
                     ALAWYRKAARQGLPAAQTHLGIMSAFGRGVAQSDRQAIAWYRKAAKQDFAKAQYQLGV
                     AYSMGRGVPENSRNALKWYLKAAEQGFTPAQLALGEIYAHGRQGVPKDNKQAYIWYYM
                     ASIYTEKSKDDCSALIAERNRLKGTLTPDQLSETYAAFDLIRRKINQSKEAKKIARKK
                     Y"
     gene            complement(8765..8896)
                     /locus_tag="OPY25_002917"
     ncRNA           complement(8765..8896)
                     /ncRNA_class="other"
                     /locus_tag="OPY25_002917"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(8947..9098)
                     /locus_tag="OPY25_002918"
     tRNA            complement(8947..9098)
                     /locus_tag="OPY25_002918"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9062..9064),aa:Tyr,seq:gta)
     gene            complement(9127..9268)
                     /locus_tag="OPY25_002919"
     ncRNA           complement(9127..9268)
                     /ncRNA_class="other"
                     /locus_tag="OPY25_002919"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(9439..10281)
                     /gene="purU"
                     /locus_tag="OPY25_002920"
     CDS             complement(9439..10281)
                     /gene="purU"
                     /locus_tag="OPY25_002920"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HCS0928486.1"
                     /translation="MQSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRVVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHETLRSLVERFEIPFELVSHEGLTREEHDTKMADAIDTHQ
                     PDYVVLAKYMRVLTPGFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYQVLAQRVFVYGNR
                     TIIL"
     gene            complement(10332..10790)
                     /locus_tag="OPY25_002921"
                     /pseudo
     CDS             complement(10332..10790)
                     /locus_tag="OPY25_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460714.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
     gene            10899..11804
                     /gene="rssA"
                     /locus_tag="OPY25_002922"
     CDS             10899..11804
                     /gene="rssA"
                     /locus_tag="OPY25_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HCS0928487.1"
                     /translation="MRKMKIGLALGSGAARGWSHIGVIKALKQTGIDIDIVAGCSIGS
                     LVGAAYACNKLSALEQWVCSFRYWDVLRLMDVSWGRGGLLRGKRVFNHYRDIMPVTDF
                     DHCSRRFGAVATNLSTGRELWFTEGDLHLAVRASCSMPGLMSPVEHNGYWLVDGAVVN
                     PVPVSLTRALGADIVIAVDLQHDAHLMQQDLLSVNVGNINEESDDALPWHKRLKERFS
                     SLTSRRGVSSSGAMEIMTTSIQVLENRLKRNRMAGDPPDILIQPFCPQISTLDFHRAH
                     AAIAAGQLAVEKKMDELIPLVRTDV"
     gene            11895..12908
                     /gene="rssB"
                     /locus_tag="OPY25_002923"
     CDS             11895..12908
                     /gene="rssB"
                     /locus_tag="OPY25_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HCS0928488.1"
                     /translation="MTQPLVGKQILIVEDEPVFRSLLDSWFSSLGATTALAGDGVDAL
                     ELMGRFTPDLMICDIAMPRMNGLKLVENLRNRGDQTPILVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLRETVFACLYPNMFNSRVEEEERLFRDWDAMVSNPTAAAQLLQEL
                     QPPVQQVISHCRINYRQLVSADQPGLVLDIAPLSDNELAFYCLDVTRAGDNGVLAALL
                     LRALFNGLLQDQLGQQKHRLPELGALLKQVNHLLRQANLPGQFPLFVGYYHSELKNLI
                     LVSAGLNATLNTGAHQVQISSGVPLGTLGNAYLNQLSQRCDSWQCQIWGAGGRLRLML
                     SAE"
     gene            13111..14019
                     /gene="galU"
                     /locus_tag="OPY25_002924"
     CDS             13111..14019
                     /gene="galU"
                     /locus_tag="OPY25_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCS0928489.1"
                     /translation="MAALNSKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLEEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGNEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGNSQIMVEPVEDVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWALLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNSLGAEFKAWLEEEMGIKK"
     gene            complement(14151..14564)
                     /gene="hns"
                     /locus_tag="OPY25_002925"
     CDS             complement(14151..14564)
                     /gene="hns"
                     /locus_tag="OPY25_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HCS0928490.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSMAAAKSGTKAKRAARPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMEEQGKQLEDFLIKE"
     gene            15227..15844
                     /gene="tdk"
                     /locus_tag="OPY25_002926"
     CDS             15227..15844
                     /gene="tdk"
                     /locus_tag="OPY25_002926"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCS0928491.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNTSLFEEIRAESARQTIHCVLVDESQFLTRQQVYQLSE
                     VVDKLDIPVLCYGLRTDFRGELFVGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQD
                     GRPYNEGEQVVIGGNERYVSVCRKHYKDALEEGSLTAIQERHRHI"
     gene            complement(16041..18719)
                     /gene="adhE"
                     /locus_tag="OPY25_002927"
                     /gene_synonym="adhC"
     CDS             complement(16041..18719)
                     /gene="adhE"
                     /locus_tag="OPY25_002927"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCS0928492.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKEATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFASHGGYMLQG
                     QELKAVQNVILKNGALNAAIVGQPAYKIAELAGFSVPETTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEEAVEKAEKLVAMGGIGHTSCLYTDQDNQPERVAYFGQMMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSVVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDNATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHALEAYVSVLASEFSDGQALQALKLL
                     KENLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLESIKAELGIPKSIREAGVQEADFLAHVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDFTEGEVAAKKDVVAAPKAEKKAKKSA"
     gene            19196..19843
                     /locus_tag="OPY25_002928"
     CDS             19196..19843
                     /locus_tag="OPY25_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchE family NAAT transporter"
                     /protein_id="HCS0928493.1"
                     /translation="MIQPLFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTATARN
                     KTNLTANLSVAIILWSSLFLGDGILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAIRESIGVVPLALPLMAGPGAISSTIVWGTRYHSIAHLLGFSVAIALF
                     ALCCWGVFRMAPWLVRLLGQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
BASE COUNT         4848 a         4884 c         5390 g         4913 t
ORIGIN      
        1 aatttaacat tcatgtcgtg cgtaaattta attttatgta attaaatcag taatatatat
       61 aaataaaact cctcctccaa aaggagtatg ccggaggttt gcgcgccatt tgcatccctg
      121 tccgccttga tcgttatcaa ttctcacgcc cattcagcgc gttaccttcg cccttagtta
      181 agcaatgtcg atttatcaga gagccgtaag gttccacaca ggagaaaccc gatgagtaaa
      241 ttcctggacc ggtttcgcta cttcaagcag aagggcgaaa cctttgccga tgggcacggc
      301 cagcttctcg aaacaaaccg ggactgggag gacggatacc gccaacgttg gcagcatgac
      361 aaaattgtgc gctcaaccca tggggtgaac tgcaccggtt cttgtagctg gaaaatttat
      421 gtcaaaaatg gtctggtgac ctgggaaaca cagcaaaccg attacccgcg cacccgtcct
      481 gatatgccaa accatgaacc tcgcggctgc ccgcgcgggg caagttactc ctggtatctc
      541 tacagcgcta accgactgaa atatccgcta atgcgcaaac gtctgatgaa gatgtggcgc
      601 gaggcgaaaa aactgcatcg cgatccggta gaggcatggg cctccatcat tgaagatgcc
      661 gataaagcca aaagcttcaa acaggcgcgt ggtcgtggcg gctttgttcg ctcctcatgg
      721 caggaagtga acgagctgat cgccgcttcc aacgtgtaca ccgtgaaaac ctatggccct
      781 gaccgcgtcg cgggcttctc acccattccg gcgatgtcga tggtttccta cgcttccggc
      841 gcacgttatc tttcgctgat tggcggtacc tgcctgagct tctacgactg gtactgcgac
      901 ctgccgccag cctccccgca aacctggggc gagcagaccg acgtgccgga atccgctgac
      961 tggtacaact ccagctatat tatcgcctgg ggctctaacg tgccgcaaac ccgtacgccg
     1021 gatgcccact tctttaccga agtacgttac aaaggcacta aaaccgtcgc ggtgacgccg
     1081 gactatgccg aaatcgccaa actgtgcgat ctgtggctgg cgccgaagca ggggaccgat
     1141 gcggcgatgg cgctggcgat gggccacgtc atgctgcgcg agttccacct cgacaacccg
     1201 cgccagtact tcaccgatta tgtccgtcgc tataccgaca tgccaatgct ggtgatgctt
     1261 gaagagcgtg atggttatta tgccgcaggt cgtatgctgc gcgctgccga tctcgttgat
     1321 tcgctggggc aggaaaataa cccggaatgg aaaaccgtcg ctatcaacag caacggtgaa
     1381 atggtggcgc caaacggttc aattggtttc cgctggggcg aaaaaggcaa atggaacctc
     1441 gaacagcgcg acgggactac cggtgcagaa actgaattgc agctcagctt gctgggcagc
     1501 caggatgaga ttgctgacgt gggcttcccg tatttcggcg gcgagggttc agagtacttt
     1561 aatcatgtgg cgctggataa cgtcctgctg cataaactgc cggcaaaacg tctgcaactg
     1621 gccgatggtt cttcagcgtt agtcactacc gtttacgatc tgaccatggc gaactatggt
     1681 ctggaacgcg gcctgaacga tgaaaattgt gccgccagtt atgatgatac caaagcatat
     1741 acgccagcat gggccgagca gatcaccggc gtgccgcggg cgcagatcat ccgtatcgca
     1801 cgggaattcg ccgataacgc ggacaaaacg cacgggcgtt caatgattat cgttggcgcc
     1861 ggtctgaacc actggtatca cctcgatatg aactatcgcg ggctgatcaa tatgttggtg
     1921 ttctgtggtt gcgttggtca gagcggcggc ggctgggcgc actacgtcgg ccaggaaaaa
     1981 ctgcgtccgc agaccggctg gcagccgctg gcgtttgccc ttgactggca gcgtcccgcg
     2041 cgtcacatga acagcacctc ttacttctat aaccactcca gccagtggcg ctacgagacg
     2101 gtgaccgccg aggagttact gtcgccgatg gcggacaaat cccgctatag cggccatctg
     2161 attgacttca atgtgcgcgc cgaacgtatg ggctggttgc cgtcggcacc gcagttaggc
     2221 accaacccgc tgtatattgc gcgtgaagcg gaaaaagccg gtatgacgcc ggtagattat
     2281 accgtcaaat ccctgaaaga cggttcgatt cgctttgccg ccgagcagcc ggaaaacggt
     2341 aaaaaccatc cacgtaacct ctttatctgg cgttccaacc tgcttgggtc ttccggtaaa
     2401 ggtcacgagt atatgctgaa atatctgctg ggtactgagc atggtattca ggggctggat
     2461 ctcggcaagc agggcggtgt gaagccggaa gaagtggaat ggcgtgacaa tggcctggac
     2521 ggcaaactgg atctggtggt gacgctggac ttccgcctgt cgagcacctg cctgtactcc
     2581 gatatcgtac tgccgaccgc cacctggtat gaaaaagacg atatgaatac ctcggatatg
     2641 catccgttta ttcatccgct gtctgccgcc gtagatccgg cctgggaatc gaaaagcgac
     2701 tgggaaatct acaaaggcat tgcgaagaaa ttctccgaag tctgtgtagg ccacctgggt
     2761 aaagagactg acgtcgtgac gctgccgatc cagcacgact ctgccgctga actggcacag
     2821 ccgctggacg tgaaagactg gaaaaaaggt gaatgcgatc tgatcccagg gaaaaccgcg
     2881 ccgcacatca tgaccgttga gcgcgattat ccggccacct atgagcgctt tacctctatt
     2941 ggcccgctga tggagaaaat cggcaacggc gggaaaggga ttgcctggaa cacgcagagc
     3001 gaaatggact tgctgcgtaa gctcaattac accaaagcgg acggtccggc gaaaggccag
     3061 ccgatgctca acacggcgat tgacgcggca gagatgatcc tgacgttagc gccggaaacc
     3121 aacggtcagg tggcagtgaa agcctgggcg gcgctgagcg agtttaccgg tcgcgaccat
     3181 acgcatctgg caactaataa agaagaagag aaaatccgct tccgcgatat tcaggcccag
     3241 ccgcgcaaaa ttatctccag cccgacctgg tctggtctgg aagatgagca tgtttcttat
     3301 aacgccggtt ataccaacgt tcacgagctg atcccgtggc gtacgctgtc tggtcgccaa
     3361 cagttgtatc aggatcacca gtggatgcgc gacttcggcg aaagtctgct ggtgtatcgc
     3421 ccaccgatcg acacccgctc ggtgaaagcg gtgatggggc gtaaatccaa cggtaatccg
     3481 gagaaggcgc tcaacttcct gacgccgcac cagaaatggg gtatccactc gacctacagc
     3541 gataacctgt tgatgctgac cttgtcgcgt ggcggcccga ttgtatggat gagtgaaacc
     3601 gacgccaaag agctgggcat tgaagataac gattggatcg aagtcttcaa cagcaacggc
     3661 gcattgaccg cacgcgcagt ggtcagccag cgtgtaccgg cgggcatgac catgatgtac
     3721 cacgcgcagg aacgtatcgt aaacctgccg gggtcggaaa ttacccagca gcgcggcggt
     3781 attcataact cggtgacgcg tattacgccg aaaccgaccc atatgatcgg cggctatgcg
     3841 cagttagcct acggctttaa ctactacggt accgtcggct ccaaccgcga tgagtttgtg
     3901 gtggtacgta agatgaagaa cattaactgg ttggatggcg aaggcaatga ccaggtacag
     3961 gagagcgtaa aatgaaaatt cgttcacaag tcggcatggt gctgaatctc gataagtgca
     4021 tcggctgtca tacctgttca gtcacctgta aaaacgtctg gaccagtcgc gaaggtatgg
     4081 aatacgcctg gttcaacaac gtagaaagta agcccggcgt tggttttcct aatgactggg
     4141 aaaatcagga aaaatggaaa ggcggctgga tccgcaaaat caacggcaaa ctacagccgc
     4201 gcatgggcaa ccgggcgctg ctgctgggta aaatcttcgc taacccgcat ctgccgggca
     4261 tcgacgacta ctacgagccg tttgattacg actaccagaa cctgcatact gcgccggaaa
     4321 gcaaacatca gccgatcgcg cgtccgcgct cgctgattac cggccagcgg atggacaaaa
     4381 ttaccagcgg gccaaactgg gaagagattc tgggcggcga gttcgaaaaa cgcgccaaag
     4441 atcagaattt cgaaaacatg cagaaggcga tgtacggcca gttcgaaaac accttcatga
     4501 tgtacctgcc gcgcctgtgc gagcactgcc tcaatccggc gtgcgtggca acctgcccaa
     4561 gcggtgccat ctacaagcgt gaagaagacg gcatcgtgct gatcgaccag gacaagtgcc
     4621 gcggctggcg tatgtgcatc accggctgcc cgtacaagaa gatttacttc aactggaaga
     4681 gcgggaagtc cgagaagtgc atcttctgct acccgcgtat cgaagcgggt cagccgaccg
     4741 tttgctccga aacctgtgtt ggccgtatcc gttatcttgg cgtactgctg tatgacgccg
     4801 atgccattga aagcgctgcc agtacggaaa acgaaaaaga tctgtaccag cgtcaactgg
     4861 acgtgttcct cgatccgaac gatccggctg tcattgagca ggcgctgaag gacggcgtgc
     4921 cgcagagcgt gatcgatgcg gcgcagcaat cgccagtgta caaaatggcg atggactgga
     4981 agctggcgct gccgctgcat ccggaatacc gcacgctgcc gatggtctgg tacgtgccgc
     5041 ctttgtcacc gattcagtct gccgccgacg cgggtgaact gggcagcaac ggtattctgc
     5101 cggatgtaga cagtctgcgt atcccggtgc agtacctggc gaatctgttg accgctggcg
     5161 acactcagcc ggtactgttg gcgctgaaac ggatgctggc gatgcgtcac tacaaacgtg
     5221 cggaaaccgt agacggtaaa gtggataccc gcgcgctgga agaggtgggt ttaagcgaag
     5281 cccaggcgca ggaaatgtat cgttacctgg cgattgctaa ttacgaagat cgctttgtgg
     5341 tgccgagcag ccatcgtgaa ctggcgcgtg acgcattccc ggagaaaagc ggttgtggct
     5401 ttaccttcgg cgatggttgc cacgggtctg ataccaaatt caatctgttc aacagccgcc
     5461 gcatcgacgc tgttgatgtg accagcaaaa cggagccgca cgcatgattg aactcgtcat
     5521 tgtttcgcgt ctgctcgagt acccggatgc tgccctgtgg cagcatcagc aggagttgtt
     5581 cgatgcgctc gcgtcatctg agaacctgga taaagaggat gcccagactc tgggcgtttt
     5641 cctgcgcgat ttaaccgcgc aggacatgct ggatgtacag gccgcttata gtgaactgtt
     5701 tgaccgtggt cgcgccacat cgctgcttct gtttgaacat gtacacgggg aatcccgcga
     5761 tcgcggtcag gcgatggttg acctgatggc acagtatgaa cagcacggtt tgcagctcga
     5821 cagccgcgaa ctgcccgatc atctgccgct gtatctggaa taccttgcgc agttgccgaa
     5881 aagcgaagcg ttaggggggg tacaggatat cgcgccgatt ctggcgttgc tcagcgcacg
     5941 tttgcaacag cgtgacagcc gttatgcggt gctgttcgat ctgctgttaa aactggcgaa
     6001 taccgttatc gacagcggca aagtggctga aaaaattgcg aatgaagcac gtgatgatac
     6061 cccgcaggcg ttggatgcgg tctgggaaga agagcaggtg aaattcttcg ccgatcaagg
     6121 gtgtggcgag tcggaaatct ccgctcacca gcgtcgtttt gccggggccg tggcgccgca
     6181 atatctgaat atcaccaccg gaggacagca ctaatgcact tcctgaatat gttcttcttt
     6241 gatatctacc cgtacattgc cggatcggta tttctgatcg gtagctggtt acgttacgac
     6301 tacggccagt acacctggcg ggcggcttcc agtcagatgc tggatcgcaa aggaatgaac
     6361 ctggcgtcaa acctgttcca cattgggatt ctgggtattt tcgccggtca tttcctgggc
     6421 atgttaacgc cgcactggat gtatgaagct tttctgccgg tcgacgtgaa gcagaagatg
     6481 gcgatgattg ccggcggcgc ctgcggaatg ctgacgctgg ttggcggtat tttactgctc
     6541 aagcgtcgtc tgttcagccc acgtgtccgc gccaccacta ccggtgcaga tattttgatt
     6601 ctctcattgc tggtgattca gtgcgcgctg ggtctgctga ccattccgtt ctccgcccag
     6661 catatggacg ggagtgaaat gatgaagctg gtcgggtggg cgcagtcagt tgtgaccttc
     6721 cacggtggcg catccgcaca tctggacggt gtagccttta tcttccgtat gcacctggta
     6781 ctggggatga cgctgttcct gttattccca ttctcgcgcc tggtgcatat ctggagcgtg
     6841 ccggtcgagt acctgacccg caaataccag attgtacgtg cgcgtcactg attttctctc
     6901 gatgccctaa actccgcttc ggcggagttt ttttatggct gtttgccgga gtgcagcata
     6961 aatgccttat cgaccgccgc cttgtttcgt ttacagcggg tctgccatgt ctggcatctg
     7021 aatccggact ctttgtttct gggtttattc agcatctgtg cgagtttttt gtaagcagaa
     7081 aaaggatgat gcagcatata atcacgccat aaacgacaat aaggatagtt gtatgcgttt
     7141 ttcatcaatt ttcaaaataa taatattaaa tatatttatt tcaaaaatgg ctcacgctgc
     7201 tgtctgcgag gagcgctatc cccccgactc agaagaatgc cagtacgttc aggaattaga
     7261 gcaaaaagcg gaacaaggag atgaaggcgc gcagttctcg cttggaagct ggtatgcgga
     7321 ggggcgatac gttaagcctg attataaact agccataaaa tggctggaga aagcgggtaa
     7381 acaaggttct gatttttcct atttcatcct tggctatcat tacaactatg gtgaaaattt
     7441 tccacttagt cggcaaaaag cgctggagtg gtatcgcaag gcggcagaac taggggatag
     7501 tagtacgcaa gaaatcctcg gtgacgccta tatgtatggc gatgggtttc cccaaaatac
     7561 ccagctagcg ctggagtggt atcgaaaagc cgcctctcca accaatgatg cgggcgttgt
     7621 ccgcggccag ggttcagctt cgtcagcaca atttaagctt ggagtaatgt acgcccacgg
     7681 tcagggcgtt cctcaggatt atcagcaaac ggcgatcttg atgcgtaaag cggcggaaaa
     7741 tatgtactac cccgcgcaac tttatctcgg tgttgcctat ttttatggtg aaggcgtgcc
     7801 tcaggattat cgtcaggcag tttactggct taatgaaggt ataccaggca gctatacgcc
     7861 aggccacatt ccgctgaatg cgctctatga taaagcgcat cccgctgacc aggttcactc
     7921 tcagacgtgg tatcgaaaaa cagcgcaacg cgtgatggca aaggtacagt tcaattttgg
     7981 cgtatggtat tacaacggtt atcacttatt gaaagatcac aatctggcgc tggagtggta
     8041 tcgcagagcc gcagcgcagg gattggccga ggcgcaggat gcgatcggcg tgatgtttat
     8101 gcagggcgag gccgtttctc aggactacca acaggcgctg gcgtggtatc gcaaagccgc
     8161 acgccaggga ctgcctgctg cgcaaacgca tctgggcatc atgtctgctt ttggtcgcgg
     8221 cgtcgcgcaa agcgacagac aggctatcgc atggtatcga aaagcagcaa aacaggattt
     8281 tgcgaaagcg caatatcagc ttggcgtagc atatagcatg ggaagaggcg tgcctgaaaa
     8341 tagccggaat gcgctgaagt ggtaccttaa agcggcagag caggggttta ctccggcaca
     8401 attagcgctt ggggaaattt atgctcatgg gcgccagggg gtgcctaaag ataataagca
     8461 ggcctatatt tggtattaca tggcaagtat atatacggaa aaatctaagg atgattgttc
     8521 agcgctcatt gccgaaagaa accgactcaa gggaacgctt accccagatc aacttagcga
     8581 gacatatgcc gcctttgatc tcatcaggcg aaaaatcaac cagtcaaagg aggcgaaaaa
     8641 gattgccagg aagaagtatt gataagatag ccaataagct atggcgccat ggtgtgaagt
     8701 ctgcctgtgg ggtaaggata cggggcagtg ctgattgatt tgaaattggt gccttatgaa
     8761 gtaatggtgg tgggggaagg atgactcagc gctgcgcgtt tcgcccttcg ggtcgttgcc
     8821 tgcggcaacg ttctctcgct ttcgctcgaa tcgaacctta gtcgaagctt ctcatccttc
     8881 cccacatggg tagaattatg acaaaccgat gtcgaatgaa ggttagatgc tttctgaaga
     8941 tcatgatggt ggtgggggaa ggatgactca gcgctgcgcg cttcgccctt cgggtcgttg
     9001 cctacggcaa cgctttctcg ctgcgctcga atcgaacctt cgaagtcgat gacggcagat
     9061 ttacagtctg ctccctttgg ccgctcggga accccaccac gggataaatt cattatgctg
     9121 cttgcattct atagcgggaa ggattattcg gagctaaagc tcctcaccct tcgggccgtt
     9181 gcctgcggca acgttctctc actattgctc gagtcgaacc ttgaagtcga tgacggcaga
     9241 tttgcagtca gctcccttat gatcgctcgg gaaccccacc acggggtaat gcttaatact
     9301 ggcccgcttc ctttcgggaa gcggggcgca tcatatcaaa tgacacgtcg ctgtaaagca
     9361 ttcctttgcc tgaaatgaac tgtttgcgta cttttcatcc gtaacggatt aaagctaatc
     9421 aattcatatt actgacgatt aaagaataat cgtccgattg ccgtaaacaa agacccgctg
     9481 cgccagaacc tgatacagcg cgcggcttaa tacgtttttc tcaacgtcgc gcccggcacg
     9541 catcatatct tctgcggtgt aggtgtgatc gacgtgaatc acgtcctgca taatgattgg
     9601 gccttcatct agattatcat tcacatagtg cgcggtagcg ccgatgattt tcacgccgcg
     9661 ctcataggcc tgatgataag gacgcgcgcc gataaacgcc ggcaggaatg agtggtggat
     9721 attgataatt ttgttcggga agcgcgccac aaaacctggc gtcaaaacac gcatatactt
     9781 ggccagcact acatagtccg gttgatgggt atcaatggcg tccgccatct tcgtgtcatg
     9841 ctcttcacgc gttaatccct catggctgac cagttcgaaa gggatctcaa aacgttcaac
     9901 cagcgagcgt aacgtttcat ggttgccaat gaccgcggcg atttcaacat ccagcccgcc
     9961 atagttggct ttcatcagca ggtcgcccag acaatgcgcc tctttggtaa ccagaatcac
    10021 tacccgacgg cgtccggcgg gattgagttc acgaacagag ccttccggta aggcgctgtc
    10081 cagatcggcc agaagagtgg aatcattgaa gatgccttcc agctcggtcc gcataaaaaa
    10141 gcgtccggtg cgatggtcca caaattcatt gttttgcaca atattaagct cgtgcttata
    10201 gcaaatgttg gtaatccgcg cgataaggcc tttttgatcg ggacaaatag tacgcagaac
    10261 tttacgttgt agtgattgca ttgccggaaa aatcctgttg agagtgtttg ctgtatcaat
    10321 actgtcaggc gtcactggcc gcagcacttt ttaaattttt tgcctgaacc gcacgggcag
    10381 ggatcatttc gacccaactg cgggcgggta ccgtcaatat aataccactg accgttttct
    10441 ttgataaaac gagaacgttc gataatcgcc ccgtttttcc cttgttcgga aaaacgcgcg
    10501 ataaaactaa cataccctgt attttctgct tctgactagg tatgttcaaa aatagtcagg
    10561 ccgagccacc tggtattggc aaatccggcg atgatatcat cacgaaacgc ggccgcattg
    10621 caagttggat gccagctctt aattaagtaa tctgcgtctt tcatcacaaa agcgcagtaa
    10681 cgagagcgca tgagatgtga cggatcgggt gctactcgtt ctccggacac aatacgacca
    10741 caacataggc tatactcgtc agcgctacca cagggacaag gctgagacac aataatctcc
    10801 ctgaatataa aacggcgttg aacgccaggg tggcattatg ttaactgagc agtggcgatg
    10861 ttgctacgtc ttgaagccag gggaagtcgt taagtacgat gagaaaaatg aaaatagggc
    10921 tggcgctggg atctggcgca gcgagaggat ggtctcatat tggggtcatc aaagccctca
    10981 agcaaacagg cattgatatt gatatcgttg caggatgctc aataggttca ctggtcggcg
    11041 ccgcgtatgc ctgtaataaa ttatcggcgc ttgaacagtg ggtatgttca ttccgctact
    11101 gggatgtttt acgcctgatg gatgtatcct ggggcagagg agggttgctt cgcggcaaac
    11161 gcgtatttaa tcactatcgg gatattatgc ccgtcacgga ttttgaccac tgttcaagac
    11221 gttttggcgc ggtcgcgacg aatcttagca cgggacgaga gctatggttt actgaaggcg
    11281 atctacacct tgccgtacgc gcgtcgtgca gtatgccagg gctgatgtct ccggttgaac
    11341 ataacggtta ctggctggta gatggcgcag tcgttaatcc ggtacctgtt tcgttaacca
    11401 gggcgctggg ggctgatatc gttattgcgg tagacctgca acatgatgcc cacctcatgc
    11461 agcaagattt gctctctgta aatgtcggga atatcaatga agagagcgat gatgcgctgc
    11521 cctggcataa gcgtttaaaa gaacgtttca gtagcctgac ttcacgccgt ggcgtgagtt
    11581 cgtctggggc aatggaaatc atgacaacct ccatccaggt gttggaaaat cgtcttaaac
    11641 gtaaccgtat ggctggcgat ccgcctgata ttctcattca accattctgt ccgcaaatct
    11701 ctacgctgga ttttcatcgc gcccatgccg ctattgcggc gggtcagtta gccgtagaga
    11761 aaaagatgga cgaacttata cccttggtgc gtaccgacgt ttaatgtacc ttttacgatc
    11821 acttaagcaa attctgacag gcgcaagcgg caataccatg ccactattga ttaaagccag
    11881 tcaggggaga gaacatgacg cagccattgg tcggaaaaca gattcttatt gttgaagacg
    11941 agcctgtatt tcgctcgctt ctggattcgt ggttttcctc tttgggagcg acaacggcat
    12001 tggcaggcga cggggtggat gccctggagt tgatggggcg ttttacccct gatctcatga
    12061 tatgtgatat cgctatgccg agaatgaacg gtctcaaact ggtagaaaac ttacgtaatc
    12121 gcggagacca gacgcctatt ctggttattt ccgcaacaga aaatatggcg gatatcgcca
    12181 aagcgttacg ccttggggtt gaagatgtct tgctgaagcc ggtaaaagat ctcaaccgct
    12241 tgcgggaaac cgtattcgct tgcttatacc ctaatatgtt taactcgcgg gttgaagaag
    12301 aagaacgcct gtttcgtgac tgggatgcaa tggtgagtaa tccgaccgcc gcagcgcaat
    12361 tgttgcagga attgcagccc ccggtacagc aggtgatttc tcattgccgc attaattacc
    12421 ggcagctcgt ctccgccgat cagcctggac tggtgctgga tattgcgccg ctatctgata
    12481 acgaactggc attttattgc ctggatgtca cccgggcggg cgataacggc gtgttagccg
    12541 cattgttgct gcgggcgcta tttaacggct tattgcagga tcagctcggc caacaaaagc
    12601 accgtttacc ggagttaggc gcgctattaa aacaggtaaa tcatctgctc agacaagcca
    12661 atttacctgg gcaattcccg ctatttgtcg gctactatca cagtgagctc aaaaatttga
    12721 ttctcgtctc cgccggattg aacgccacct taaatacggg cgctcatcag gttcaaatta
    12781 gcagcggcgt gccgctagga acattgggta acgcctacct taaccaatta agccagcgtt
    12841 gcgactcgtg gcagtgtcaa atatggggcg caggagggcg tctgcgattg atgttgtctg
    12901 cggaatgacc aaacggaaga gtgagcggaa attgctttac cggcctttcc cgacgagtgt
    12961 tactatctgc ggcagattta taagtatttg tcttaattat accaatataa gtcctttttg
    13021 gacctgaggc ttgttctggt actgatatac tggaacacga tacagattaa tgaacacgtt
    13081 caatacatga acagtccagg agaattttaa atggctgccc ttaattcgaa agtcaaaaaa
    13141 gccgttatcc cggtcgcggg attgggaacc aggatgctgc cagcgaccaa agctatcccg
    13201 aaagagatgc tgccgctggt tgataagcca ttaattcagt acgtcgtgaa cgaatgtatc
    13261 gctgctggca ttactgaaat cgtgcttgtt acgcactcgt ctaaaaactc tattgaaaac
    13321 cactttgata ccagttttga gctggaagcg atgctggaaa aacgcgttaa gcgtcagctt
    13381 ctggaggagg ttcagtctat ttgccctccg catgtcacta ttatgcaggt acgtcaaggg
    13441 ctggcaaaag gcctgggcca tgccgtattg tgcgcgcatc ccgttgtcgg aaacgaacct
    13501 gtcgctgtta ttctgccaga cgttattctt gacgaatatg agtccgacct gtctcaggat
    13561 aacctggctg aaatgatccg ccgtttcgac gaaaccggca atagccagat tatggttgag
    13621 ccagtagaag atgtgactgc atacggcgtg gtcgattgca aaggcgttga gctggcgccg
    13681 ggcgaaagtg tgccgatggt tggcgtggtt gaaaaaccaa aagcggatgt cgcgccgtct
    13741 aaccttgcga ttgtcgggcg ttatgtgttg agcgcggata tctgggcgtt gctggcgaaa
    13801 acccctccgg gcgccgggga tgaaattcag ttgaccgatg ctatcgatat gctgatcgaa
    13861 aaagaaacgg ttgaagccta ccacatgaag ggtaaaagcc atgactgtgg taataagtta
    13921 ggatatatgc aggcattcgt tgaatatggc atccgtcata attcgctggg tgctgaattt
    13981 aaagcctggc ttgaagaaga aatgggtatt aagaagtaac gatacgttat aaatttttta
    14041 acagaagcgc tggtaaatcc ggcgcttttt ttatgcctgg ggtcgtcagc ggagaactca
    14101 ggcaaaaaaa atcccgccag cggcgggatt ttaagcatcc aggaagtaaa ttattccttg
    14161 atcaggaaat cttccagttg cttaccttgt tcttccattg cttttttgat tacagccggt
    14221 gtacgaccct ggccagtcca ggttttagtt tcaccgtttt cgtcaacata gctatattta
    14281 gccggacgag ctgcgcgttt agctttggta ccggatttag cggcagccat gctattcagc
    14341 agttcattcg ggtcaatgcc gtcggcaatt aacatttcac gatactgttg cagtttacga
    14401 gtgcgttctt ccacttcagc agcagcagcg ctttcttctt cacgacgctc attaacgaca
    14461 acttctaatt tttccagcat ttcttcaagc gtttccagag tacattctct tgcctgcgca
    14521 cgaagagtac ggatgttgtt cagaatttta agtgcttcgc tcattgtagt aatctcaaac
    14581 ttatattggg gtggtttgtt gagctaataa tagagcgata aattcagttg tgcaatagcc
    14641 aggaatgtaa ggaattcaaa attacgcttt attaagcaca cgttttaatt atctcaactt
    14701 aaattttcct tgaggcgccg cacaaaaaag agcttattgc caggggggat actcaccgtc
    14761 tgtcactaaa aatttaggat tcaggtcaca ttttatcatg atgaaatacg atctcattgc
    14821 agagatatca atctcttgta ttagctttcc ttacaagaaa accctattac tttgcattgg
    14881 gtatgagtaa cggtaacaat aagtacaagg ttttcatatt ggcgggtgat gataagcatt
    14941 gttgatgaat tttaacggca taatttgtga aggaatgtgt atataccctt catacttcaa
    15001 gttgcttatg tgttggctac gctcgcgcac cccagccaca tagttatcta tgctcctggg
    15061 gactcactcc cttgccgcct ttaagcaact cgaattattt tgggtatagt gagcgatgtt
    15121 tgtacaattc ttaatactca ccggagcgcg agccgcgccg tcgcatcggt aaattatggt
    15181 acaatcccgc caatctttat ttcactcagg tgaggtcctg cgaccaatgg cacagctata
    15241 tttctactat tcggcaatga atgcgggtaa gtcgactgca ctgctgcaat cttcatacaa
    15301 ttatcaggaa cgcgggatgc gtaccgtcgt atatacggcg gaaatcgacg atcgtttcgg
    15361 cgcaggcaaa gtcagctctc gtatcggttt gtcgtcgccg gcaaaattgt ttaaccaaaa
    15421 tacatccttg tttgaagaga ttcgtgccga gagcgcgcgg cagacaatac attgcgtgtt
    15481 agtcgacgaa agccagtttt tgactcgcca gcaggtttat caattatccg aggttgtcga
    15541 caaattagat attccagtac tctgctatgg gctacgaaca gactttcgtg gggagctctt
    15601 tgtcggcagc caatacttgc tggcatggtc agataagctg gtggaattaa aaactatctg
    15661 tttctgcggt cgtaaagcca gtatggtttt gcgccttgat caggacggca ggccttataa
    15721 cgaaggcgaa caggtggtta ttggcgggaa tgaacgctac gtttcagttt gccgtaagca
    15781 ttataaggac gcgctggagg agggctcact gacggcgatt caggagcgcc atcggcacat
    15841 atgatacctg aggtaaagat cggcttataa aacgccctgt agcgctttgg aggtcattat
    15901 tcaggcctcc tgacgaaggg cgtgccgtga gcgcgtaggc cagatggtaa gcatagcgcc
    15961 ttcaggcatc agataaacag gtaaaacaaa aaaacggcct caattgaggc cgttattgtc
    16021 atgctaaaac agataacgaa ttaagcggat tttttcgctt ttttctctgc tttcggtgcg
    16081 gcaacgacgt ctttcttcgc tgcaacttca ccttcggtga aatcacgacc gtagtaggta
    16141 tccagcagaa tctgtttcag ttcggagatc agcggataac gcgggttagc gccggtgcac
    16201 tggtcatcga aggcatcttc agacagtttg tcaacgtgtg ccaggaagtc agcttcctgc
    16261 acgcctgctt cacgtataga cttaggaatg cccagctcag ctttaatgct ttccagccat
    16321 gccagcagtt tttcaatctt agcggcggta cggtcgcccg gcgcgctcag gcccaggtgg
    16381 tcagcaattt cagcgtaacg acggcgtgcc tgcggacgat cgtactggct gaaagcggtc
    16441 tgcttggtcg ggttgtcatt cgcgttgtag cggataacgt tacaaatcag cagggcgttc
    16501 gccagaccgt gcggaatgtg gaactgagag cccagtttgt gcgccatgga gtgacataca
    16561 ccgaggaagg cgttggcaaa cgcgataccg gcgatagtcg ctgcactgtg aacacgttca
    16621 cgcgcaaccg ggtttttaga cccttcgtgg taagacgccg gcaggttttc tttcagcagt
    16681 ttcagagcct gcagagcctg accgtcagag aactcagaag ccagtacgga aacgtaagct
    16741 tccagggcgt gagttaccgc atccagacca ccgaacgcac acagggactt cggcatatcc
    16801 atcaccaggt tggcatcgac aatcgccata tccggggtca gggcatagtc agccagcgga
    16861 tatttctgac cggttgcatt gtcggtcaca accgcaaacg gtgtgacttc agaaccggta
    16921 ccggaagtgg tggtgacggc gatcattttc gctttcacgc ccattttcgg gaacttgtag
    16981 atacgtttac ggatgtccat aaagcgcagc gccagttctt cgaagtgagt ttccggatgt
    17041 tcgtacatga cccacatgat tttcgcggcg tccatcgggg aaccgccgcc cagcgcgatg
    17101 atcacgtccg gtttgaagga gttagccagc tcagcgcctt tgcgaacaac ggaaagcgtc
    17161 gggtctgctt caacttcgaa gaagacttcg gtttcaacgc cagccgcttt cagcacagag
    17221 gtgatctggt ctgcatagcc gttgttgaac aggaagcggt cagtcacgat gagcgcacgt
    17281 ttgtggccat cagtaatcac ttcatccagc gcgatgggca gagagccacg gcggaagtag
    17341 atagatttcg gaagtttgtg ccacaacatg ttttcagctc gcttagcaac ggttttcttg
    17401 ttgatcaggt gtttcggacc aacgttttca gagatggagt taccacccca ggaaccacaa
    17461 cccaacgtca gggaaggtgc gagtttgaag ttgtacaggt caccgatacc accctgagag
    17521 gccggggtgt tgatcaggat acgcgcggtt ttcatcatct gaccgaagta agcaacgcgt
    17581 tctggctggt tatcctggtc agtgtacagg caggaggtgt gaccgatacc gcccatagcg
    17641 accagttttt ctgctttttc taccgcttct tcgaaatctt tcgcacggta catcgctaga
    17701 gtcggagaca gtttttcgtg tgcgaacggt tcgctttcgt caacgaccgt aacttcaccg
    17761 atcagaatct tggtggtttc tggtacggag aagcctgcca gttcagcgat tttgtaggct
    17821 ggctgaccga cgatagcggc gttcagagcg ccatttttca gaataacgtt ttgaaccgct
    17881 ttcagctcct ggccctgcag catgtagccg ccgtggctgg cgaaacgttc gcgaacggca
    17941 tcatagacgg aatcaacaac gacaacagac tgttcagaag cacagattac gccgttatcg
    18001 aaggttttag acatcagaac agacgccaca gcgcgtttga tatcagcggt ttcatcaatg
    18061 acaaccgggg tgttacctgc gcctacgccg attgccggtt taccggagct gtatgcagct
    18121 ttaaccatgc ctggaccgcc agtggcgagg atcaggttaa tatccgggtg gtgcatcagc
    18181 gcattagaca gttctacgga aggttgatcg atccagccaa tcagatcttt cggtgcgccg
    18241 gcagcgatag ccgcttgcag aacgatgtct gccgctttgt tagttgcttc tttagcgcgc
    18301 ggatgcggag aaaagatgat ggcgttacgg gtcttcaggc taatcagcga tttgaagatc
    18361 gcagtagagg tcgggttagt ggttggaacg ataccgcaaa taatgccgat aggttcagca
    18421 atggtgatgg tcccgaaggt gtcgtcttct gacagcacgc cgcaggtttt ttcatcttta
    18481 taggcattgt aaatatattc agaagcgaag tggtttttaa tcactttgtc ttccacgata
    18541 cccatacctg attcggcgac ggccattttg gccagcggaa tgcgggcatc agcggctgcc
    18601 agagcggcgg cgcggaagat tttgtcgacc tgttcttgag tgaaactggc atattcacgc
    18661 tgggcttttt ttacacgctc tacgagtgcg ttaagttcag cgacattagt aacagccata
    18721 atgctctcct gataatgtta aactttttta gtaaatcatc tgcgcgatac gtgagtatag
    18781 acagatcgac gatactttgt ataaatacct gaaattcagg tggttactta acgtccgttt
    18841 cgctctgatt tactaaaaga gcttctgcgt tagtatcatt taactctaac gcgttacgtc
    18901 caggtggcgt aagcaagatt actcacttct gagtagcgat tgtgtgatct aaatcaagat
    18961 tacgcaaagc tgacaccttt cagcaggcca ttttagcctt ttatgtaaat tgttaagaaa
    19021 tcgttgtcat gaagagtaag tggattagca taacgagtac atataaataa cagcgatgaa
    19081 tggatgaaat taggtgtaga taagaggtga actatgcgaa taaaaggcgt atcttctgcg
    19141 cgttttgatc attaacgaac attgacttca tccggctaac gcttcggagc taaccgtgat
    19201 tcaaccgctt tttgattttc ctgtttactt taagttcttt atcgggctct ttgcgctggt
    19261 taacccggtg gggattattc ccgttttcat cagcatgacc agctaccaga cggccacggc
    19321 gcgtaataaa actaacctca ccgcgaatct gtcggtcgcg attatcttgt ggagttcctt
    19381 attcctcggc gatggcatcc tgcagctgtt tggtatttct attgattcgt tcagaattgc
    19441 gggcggtatc ctggttgtca ccattgcaat gtcgatgatc agcgggaagc tgggggaaga
    19501 taaacaaaac aagcaagaaa agtcagagac ggccatacgc gagagcattg gcgttgtgcc
    19561 gttagcgcta ccgttaatgg cggggccagg ggcgattagc tccactatcg tctgggggac
    19621 gcgttatcac agcatcgcgc atttgcttgg tttttcagtt gccattgcgc tttttgcgct
    19681 ttgctgctgg ggcgtgttcc gtatggcgcc gtggctggtt cgtttgctgg ggcaaaccgg
    19741 tatcaacgtt attacccgaa tcatggggtt gttgttaatg gcgctcggca tcgaatttat
    19801 tgtcacagga ataaaaggca ttttccccgg cttgctcaac taaactccca cctgttgatt
    19861 tacaggcggc gccctaaggg ggccgccttg tgacattccc agtgacattc ccacgtaaca
    19921 cttcttactt tgataagcat tcagcgttta aatgataaaa aatactaata taatctaacg
    19981 ctatttattt ttattaatca atctattatg aacattactg agaccgtgag aagcg
//
LOCUS       DAJVKX010000080        19824 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.080, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000080 DAJVKX010000000
VERSION     DAJVKX010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 19824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19824
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.080"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(299..907)
                     /locus_tag="OPY25_002929"
     CDS             complement(299..907)
                     /locus_tag="OPY25_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HCS0928494.1"
                     /translation="MKVIWTVTPVGYQRIAKRCPSCSVKRDFTPSGAFRVNSQKKVLD
                     VWSIYKCTHCDYTWNISLFSRLPVSKINRNLYCRLMANDAATVQYFAYDNAILKRNNA
                     ELSGQPDFHIQERWLVSIASHKQVSVSVRISRSFQVSLLSILKKQLLLSAAEIKRRIE
                     TGQISGVTMKMLKSRKLKNAKYDLQLSVETLYDRRRIVLTRR"
     gene            1395..1652
                     /locus_tag="OPY25_002930"
     CDS             1395..1652
                     /locus_tag="OPY25_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjhX family toxin"
                     /protein_id="HCS0928495.1"
                     /translation="MNLSRQEQRTLHVLAKGGRITHIRDASGRVTAVECYSREGLLLA
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQPDNR"
     gene            1657..3288
                     /locus_tag="OPY25_002931"
     CDS             1657..3288
                     /locus_tag="OPY25_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HCS0928496.1"
                     /translation="MMMDISAVIFATHRIRLLPDEGKIPWDEPAFSQRMLENHLSQDH
                     DWASRRLTVIEQQVTWITRQLPAGARILDLGCGPGFYTRLLAERGFHCTGVDFSPASI
                     TWARQQAQAANLNIDYIQQDIRTYHPTEPFDFIMMTFGELNVFSAADAQSLISHCAQW
                     LKPDGKLLVEVHTFDEVKRQGMAQPGWQRCPHGLFLAVPHLLLTENAWDEEAQTSSTQ
                     FWAIAENGCTTRFGSQMKAWRDDEYISLLGDAGFTVLQRPDSHTWPVGETFAGKLFAL
                     LAEKASTSEGIALSKRNNPMDIPRIFTISESEHRIHNPFTAEKYATLGHALRMKPGMR
                     ILDLGSGSGEMLCTWARDYGVTGTGIDISPLFTTQAKQRAEELGVSEYVHFIHNDAAG
                     YIDEEKYDVAACVGATWIAGGVAGTIDLLAKSLKPGGIILIGKPYWRQIPATEEIAHA
                     CGVSSVADFRPLPELVAFFDQLGYDVVEMVLADPQGWDRYEAAKWMTMRRWLEENPDD
                     EFAQEVRTELTAAPKRHVTWTREYFGWGVFALIAR"
     gene            3701..4417
                     /locus_tag="OPY25_002932"
     CDS             3701..4417
                     /locus_tag="OPY25_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCS0928497.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYAAAKQGEPDPESN
                     SALKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMVIAETLTSN
                     VNRTIANIRTIFNKKGGNIGAAGAVSYMFDNTGVIVFKGTDPDHIFEILLDAEVDVRD
                     VTEEEGNIVIYTEATDLHKGIAALKAAGITEFSTTELEMIAQSDVELSPEDLEIFEGL
                     VDALEDDDDVQKVYHNVANL"
     gene            complement(4898..5773)
                     /locus_tag="OPY25_002933"
     CDS             complement(4898..5773)
                     /locus_tag="OPY25_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCS0928498.1"
                     /translation="MTSDKTLKQAISNITIWRKGEQRAPHKPLLLLYVLSHYRQGHDR
                     LFDYGSEIHEQLLDLLERYGPQRREQRPDMPFWRLKGDGFWELQNAEFCSTSGSRQPP
                     KRELIEYNVAGGFDAVNFALVTKKRKLIDTLAQQILEAHFPTSIQEDIADEMGFDIRT
                     SFRQRDPKFRQAVLRAYNYQCAVCGFNMRHDNAPIALEAAHIRWKQHHGPCEVPNGLA
                     LCAIHHKAFDRGSIGLDENMRVVVSDAVNGGGVVQRLFWDFAGKEIALPPVKENYPGE
                     RFVEWHRKEVFRGEH"
     gene            complement(5851..6090)
                     /locus_tag="OPY25_002934"
     CDS             complement(5851..6090)
                     /locus_tag="OPY25_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928499.1"
                     /translation="MVPAFFLPACLQRSDMELNNEYQNYEDEDDESADDLPPSHHPRS
                     FQSIIGWLYDKAVSGIAGIESAEMLAARYLEDAKG"
     gene            6354..9653
                     /locus_tag="OPY25_002935"
     CDS             6354..9653
                     /locus_tag="OPY25_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928500.1"
                     /translation="MSQSEYASILKCTPWLAKFLTRRGLKQPDHRPLYEYHATSEEYD
                     ELKRLLRAIGVPDGYKSDKGYAACFTLFCSEWYRRDYEREYGWAWEPIYKTIGISASS
                     SKMGKIIPKGLDGYWGRPVRFYDTERRNFLGSLFSEGGLPFRLLKESNSRFQSMFSLI
                     LNQYDQAKSSNISTFALVHAAVEKSSLPVVFKEDTSVELISRMAEQLVSLVQIYDLSN
                     HTEPVKELERVHPKWRDSFPVPLDDDTGTSFLNGLLRTASTESKPRLQKNKTTLCQFL
                     WSENHPEALQALISLPEELSFSIDIEPSTTRFELAIYEDGNEIASLGPAYATLSNSQA
                     KIKVRKREIKFYRRNPTVSLFIVARAGGMFFGSNLLEGSEVAVGDVPLVFVSDKNEWL
                     LQGQASCSVRGSHVLIVLPKDGCLASEHEDCDSGFSALGCHALTIKGRQDIIIKGDET
                     YRIKIGRDQIIHTGFSFQGKRLNWTSYPDELFLGVPGITQHSENLSTRHYKRFFNGTF
                     IENCDVQEKMGAQFISVRNENDETLLRKKIGILPNDFSLEIKNGQQANEGSVIITTQH
                     PCLYSLKEKTLEVGRKRLPDSTEIMMKAEGIPPASISLQITPNLTANPIVIWLPFPAR
                     GCLAFDKDEKPLPKNLTINDLLGARAYLFGKNGEPTRYQLELRLRSRSGMQAWYEWHY
                     SAGECPVELTLYSLREHIDNLLSLEEGIDQTVDMRIKGGGSSFTWQIRRYKYSLDYDR
                     GRQILLANSISNRTGQIPSPVIMLLSEPERKVVLLTSRMSEGVPVGEFELSSIIQKNG
                     PWLVLPKPGEEASFRPCFIAGEPVIQSDATAIQSLQKATQLFNPRSDVNTIMLVLEQM
                     ASDPAHSGWQFLRNLYDQFGYLPLATFEVWRALVQHPQALAMSLFKFEMSIDYLSRIE
                     SEFPVFWEFLSITEVKRSATRFRAFLTHKGAPEEMQIRLLYRMYQQLGTTFPTYASEV
                     QLWLSQGKLPPVFPELTMKGIILEWYQELLREHGESRWPEFGGPGLLRWYMSQQNPVI
                     DISPDASYRYSVTLLPVFAAAVASGKTTFESVFENKPGAVFFLRQVRDFDSRWFNAIF
                     QYCLLRNVTEK"
     gene            9666..12203
                     /locus_tag="OPY25_002936"
     CDS             9666..12203
                     /locus_tag="OPY25_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCS0928501.1"
                     /translation="MTTRYFSSLIEQSLSRSTEATLSIMGVTNPNLREHLTQQMAADC
                     GKEGSFLASPVFEQTFGWKESNSTMKDLATKQTLLSKEVVDSLDSEENGRYRFGSDWK
                     PFTHQLASWQSLLEKKHSVVVTSGTGSGKTECFMVPVLEDLYRELQVKNKKPLIGVRA
                     LFLYPLNALINSQRERLDAWTRSFGSGIRYCLYNGNTEELHALVKSEQANRPNEVLSR
                     EKMREEPAPILVTNGTMLEYMMVRQVDAPIIQKSKAEKSLRWIVLDEAHTYVGSQAAE
                     LALQLRRVMTAFGVTPDDVRFVATSATIAGSDAEKQLKKFLSELSGVPQERIDVLGGS
                     RVIPELEPCKQYSLSLDEIEHIPDSESEGISPERYSALTHSPEARCLREMLVSQPRPM
                     KLDTLTQRLNELTKHQYTQQDVLRWIDLCSGTLPNAKDPAFLKVRAHIFQRNTQGIWT
                     CVDKNCAAKKNTALEKNWSFGNVYVNQRQNCECGSPVFELAFCNECNEPHLLARDKKG
                     KLVQWDNKGGDEFSLQDEISDDFETSGEKIQKDFVFQSPQIIAAECNTEAGYIMQRLD
                     RQTRSIGVVNPDSIPLAINDIEQICSASNCGYKGGKGKQPFRRALLGGPFYVTNIVPT
                     VLEYCQDFTSDEGKDGVGPLSLPGRGRRLITFTDSRQGTARMAVRMQQEAERSRLRGS
                     VVEILGWHQRKQPTSAPNDQADVMKLVARVTQYREEAREYREWGMPEEAKLSEAQAER
                     LEQAIQTATGGKAATILVCRTWTEMVNDLKEKADIQGPILQYNHYLKPEIFTENGGPL
                     KLAEMLLFREFMRRPKRTNSLETQGLVQVGYQGLEKAGSQCSYSLAG"
     gene            12241..15990
                     /locus_tag="OPY25_002937"
     CDS             12241..15990
                     /locus_tag="OPY25_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HCS0928502.1"
                     /translation="MTLDFYVRESNYIQLDDDLRNWIGSRFSSKFVRNPDSKEPDDNQ
                     VKRWPQIRHGNVTQRLVKLLILGAKFNTVNTVTIDIVNAWLKEAWLQLTGSLAVLKPD
                     GNRFYLPKEHLTFSLVQKARICPVTNKLLATTFKGLTPYLPMHIQFERLTSAQYDAFL
                     AQEVTLPAIWEHDRSQDDYVDGLTKVRDWVSQDPQVLPLRSQNLWTDINDRVVEGGFY
                     YRTAEHSAQQSSERLQSYERMFKNGQLNVLNCSTTMEMGVDIGGISAVVMNNVPPHPA
                     NYLQRAGRAGRSKESRAISYTLCKGNPHDQQVFANPLWPFETVIPAPMVAMNSERLVQ
                     RHVNSLLLSEYLCHVVGETEKERTSLNSQWFFGEELDQSVCNRFKAWLERPTLSIDNA
                     LERLVKGTALHGVTAEKLRDKTQEAIAVLQTRWLGIFRDLVKQESESQPNTPYRRRLE
                     LEKKRHCGEYLLRDLAARTFLPGYGFPTDVVTFDNFTMEDYIREKTHKSRDKNDREDN
                     VSRYKGLPSRNLSVAIREYAPGAEIILDGRVFRSAGVSLHWHNLNADTNEAQRLDSAW
                     RCHKCGTLGYEEGIGGSGDLFCTNSACGERITLDNRRQVLQPAGFVTDAHTPVTNNIE
                     TMKFIPVVPAWVFVKAERVPLPNPLMGFMASGADGHVFQQSMGEGGHGYALCLSCGRA
                     ESMLNATDTPKSMEAHYPPRPGKSDRDSQNQRIICPGSTALNKNVTLGALARTDVFEL
                     ILRRPQNGEYIPDNSDEGRIVAMTLAVALRRALASVLGVSATELGYAVRPVRLDNEQS
                     VLAVQLYDIISGGAGFASSAPLHIEAVLKGMVKQLGCRHCDTACSECLLDSQTRHDHD
                     QLDRKAAQAWLGEDFSHYIGLPEAEKFSLADAQYCPGSIEDAIRRAINDGARKLTLWM
                     NGPLNEWDLYARQFRTAIQNYRLKDEVEVTLVVPGHIEDPELLQEIAQFAAIGMQLCQ
                     SELNTDTPVVAQVAFNDRLMMLISRSPEATIPGPNWHLNSQMVIRSHAFEPITLSKAE
                     LLSDAAGSRGLVNDIEIHKQLNGPVSQFGQRFWGVLTGAQEDIQTLLKENQVTRIHYS
                     DRYLQNPVALALLGGLLKPLKSILAQDAQVTIDTLFKSKERPGNKPFHDWMSEADFQD
                     FADQWFAASMGRAVVVNTVGSPRDIPHHRKLMVTFSNGQALKIRFDQGMGYWRIVFAR
                     AYRDFDFNDDVAFQLGNMAKACVEGQVVNSEESWATDVLVQVIVP"
     gene            complement(16101..16935)
                     /locus_tag="OPY25_002938"
                     /pseudo
     CDS             complement(16101..16935)
                     /locus_tag="OPY25_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611505.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(17198..18043)
                     /locus_tag="OPY25_002939"
     CDS             complement(17198..18043)
                     /locus_tag="OPY25_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HCS0928503.1"
                     /translation="MFRYLCNQKAALLTAILLMAAGVLTLCFPESWYPQETEWQLTAE
                     KEITGIHGGLSGLTWNPDSRTLFAVTDHPSSVVELDTEGNVLRVIPSDGDHDFEAIEY
                     LGGNRYALSRERERTLTTHCIDSSTTVLPPATYSLTLDVNRHSDNAGFEGLAWGRGEH
                     ALMVAQEKKPLRLYVTDRSPDALSVSDSLTHRASLPWFLKDISGLHYDRNNGLLYVLS
                     HESAVVVVSDLDGGRKVMSLRRGHCGLRRDIPQAEGIASDDRDTLWIVSEPNLFYRFT
                     RTASS"
     gene            complement(18094..18240)
                     /locus_tag="OPY25_002940"
     CDS             complement(18094..18240)
                     /locus_tag="OPY25_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928504.1"
                     /translation="MPTDDKGTIQAGDIPPLRALILLLLTSVFISGFLTGVLAMLWLI
                     CRGA"
     gene            complement(18230..18766)
                     /locus_tag="OPY25_002941"
     CDS             complement(18230..18766)
                     /locus_tag="OPY25_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCS0928505.1"
                     /translation="MADAPAEVELFFFYCPPCYAFSQTMGVARAIRHVLPHGDRMIKY
                     HVSLLGPLGHELTQAWALAMMMKETDVVEKAFFTADMVEKRLHSPDDVRRVFMSATGI
                     SRGEYDRSIKSPAVNDMVALQERLFKEYGVRGTPSVYVRGRYHINNAAFGAFSVEDFR
                     SRYAAVVRKLLAGNPDAD"
     gene            complement(19129..19479)
                     /locus_tag="OPY25_002942"
     CDS             complement(19129..19479)
                     /locus_tag="OPY25_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0928506.1"
                     /translation="MASALTAFPEDGDISRIWYDRLCIEFNSDGGLSPAELRVIRLLL
                     QGYNCGQIAALCFRSVKTISAQKGLAFRRLGVRNDATLLPTLMLLGMVTLYTDLNRCH
                     SLEESGPECGSEAG"
     gene            complement(19464..19673)
                     /gene="pefI"
                     /locus_tag="OPY25_002943"
     CDS             complement(19464..19673)
                     /gene="pefI"
                     /locus_tag="OPY25_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PefI"
                     /protein_id="HCS0928507.1"
                     /translation="MGESIITNIISIIRERQSTDNAPVKIRDIADAAGLSIYQVRSYL
                     EQLRAVGVLEKVNAGKGAPGLWRLL"
BASE COUNT         5162 a         4815 c         4931 g         4916 t
ORIGIN      
        1 cagtggttca ggtattaata tcagctcaac agtgagccat ttcttcttat tttttaatgg
       61 tgttgcgtga atatttattt actctacaga taaagataat tgtaacccat cgccctttgt
      121 cattctgctg atcatcactg gtgcgaaaac gtctggatta tccgtggcga ttcagtcttc
      181 actgaatgcc acagacaagc gttattcaac taaagctcac ctgtccctta gtccttcttt
      241 cattccgttg cgtcgttgcc ataccagcac acttaaacgt aaggtgagct tattgttttt
      301 atcgacgggt cagaacaatc cttcgccggt catacagtgt ttcaacagag agctgcaaat
      361 catatttcgc attcttcagt tttcgcgatt taagcatttt catcgtgacg ccacttattt
      421 gccctgtttc aatccgtctc ttgatttcgg ctgcgcttag caggagttgc ttcttcaaaa
      481 tcgacagcag gctgacctga aaagaacggg aaatcctgac gctaacactg acctgcttgt
      541 gggaggcgat actgaccagc caccgttcct gaatgtgaaa atcaggctgc cccgataatt
      601 cagcattgtt tcgcttcagg atcgcgttgt cataagcaaa atattgcacc gtggcagcat
      661 cattcgccat cagccggcaa taaagattgc ggttaatttt gctgactggc aggcgcgaga
      721 acagggagat attccaggtg taatcgcagt gtgtgcattt atagatactc cagacatcga
      781 gtaccttctt ttgcgaatta acccgaaatg ccccagaagg cgtgaagtcc cgttttacgc
      841 tgcatgaagg gcaacgtttc gctatgcgct gataccccac aggagtgaca gtccatatga
      901 ctttcataac gtaccttttt taacccatac aaaaccggat ccgaactcag cggaccataa
      961 atgtttgtgt atgaaaaata tttaagtgat atttttcagc gggttaaaaa aagatttcca
     1021 acgctacaac cctgtcaacg gccaaaagat acgtcgagac tatcaaagcg gccattatcg
     1081 ggtatatgag tttaatcaat attcattatg gtaattgcgg gagctattca tctgatacgc
     1141 taaacgtcat gagcctccct ttgagatcac acttttcact cccggttatt cacttacaga
     1201 aatcaggtgt tatcattcac tacgtaaata cctttcaact caacccgagg ctttgatgct
     1261 ggagaatgtc atcatctgat aatcagttac ccgacctttt caggccggac tgattatcaa
     1321 tgcgccgaaa tcgaatgcgg acaccgcagt gtgtttgcac gttttgccta tgatgattaa
     1381 acaggttctt cagtatgaat ttatcccgtc aggaacaacg taccttacac gttctcgcca
     1441 aaggcggacg cattacgcac atccgcgatg cgtcaggccg cgtcaccgcc gttgagtgct
     1501 atagccgcga agggttgttg ctcgccgatt gcacgctcgc tgtattcaaa aaactcaaaa
     1561 ccaaaaagct gatcaaatcc gttaacggtc agccctaccg cattaataca accgggctga
     1621 acaacgttcg cgcccagcct gacaatcgct aaggagatga tgatggatat cagcgccgtt
     1681 atttttgcaa cgcatcgcat tcggctatta cccgatgaag gcaaaatccc ctgggacgag
     1741 ccagccttca gccaacgcat gctggaaaat catctgtcac aggatcacga ctgggccagc
     1801 cgccggctaa ccgtgattga gcaacaggta acatggatta cccgtcagtt acccgcaggc
     1861 gcccgcattc tggatctcgg ctgtggcccc ggtttttata cccgcctgtt agcagagcgt
     1921 gggtttcact gcacaggcgt agatttctct ccggcatcca tcacatgggc tcgccagcag
     1981 gcgcaagccg caaacctgaa tattgactac attcagcagg atattcgtac ataccacccc
     2041 acggaaccct ttgatttcat tatgatgacg tttggggaac tgaatgtctt tagcgctgct
     2101 gatgcgcaaa gcctcatcag tcattgcgcg cagtggttga aaccggacgg caaactgctt
     2161 gttgaagtgc ataccttcga tgaagttaaa cgccagggca tggcgcagcc aggctggcag
     2221 cgttgtccgc acggcctgtt tcttgccgtg cctcatctgc tgttaacgga aaatgcctgg
     2281 gatgaagagg cccaaaccag ctcaacgcag ttctgggcga tagcggaaaa cggctgtacc
     2341 acccgtttcg gcagtcaaat gaaggcctgg cgcgatgatg aatatatcag cctgcttggt
     2401 gatgctggct tcactgtgtt gcagcgcccg gacagtcaca cctggccggt cggcgagact
     2461 tttgcaggca agctgtttgc gctgctggct gaaaaagcat ccacttctga gggtattgcc
     2521 ctcagtaaaa ggaataaccc aatggatatc ccacgtattt ttaccattag cgaaagcgaa
     2581 caccgtatcc ataatccgtt tacagcggaa aagtacgcca cgctgggcca tgcgttacgc
     2641 atgaaaccag gcatgcggat tctcgatctc ggtagcggtt cgggtgagat gctctgcacc
     2701 tgggctcgcg attacggtgt tacaggtact ggcattgaca taagcccgct cttcaccaca
     2761 caggcaaaac aacgtgcaga agagctcggc gtcagtgaat acgtacattt tattcataac
     2821 gacgcggccg gttatatcga cgaggaaaaa tatgacgtgg cggcctgcgt aggcgctacc
     2881 tggattgcgg gcggtgtcgc ggggacaata gatctgctgg ccaaaagcct caaacctggc
     2941 gggatcattc tcatcggtaa accgtactgg cgtcagatcc ccgcaacgga agagatcgcc
     3001 cacgcctgtg gcgtctcatc cgtcgccgat tttcgccccc tgcccgagct ggtcgccttt
     3061 ttcgaccaac tcggctatga cgtagtggaa atggtgctgg cggacccgca aggctgggac
     3121 agatatgaag ccgctaagtg gatgaccatg cgccgctggc tggaggaaaa ccctgacgat
     3181 gagtttgcgc aagaggttcg aacagaactg acggcagccc ccaaacgtca cgtcacctgg
     3241 acgcgagaat actttggctg gggcgtattt gcgttaatcg cgcgataacg tgaagcagga
     3301 ggtataccct acaagaggta tacctccatt taaaagtatt caacaaatta acacggctca
     3361 aggcgggaat atatcgtctt aatttcgcca ttaagtttct gccacaatat gtcgcaagac
     3421 gtgcaagcgt tccacctcac ctgatgagcg aaaccaccat caataagacg ttattgctgc
     3481 gattcaatta ttaagaataa aaaaagaacc agaagaaaat taaaaaatga cttacccacc
     3541 atattagcca ttgttaaaat caaagtaccc ccctcgtaaa agctggatgt atttatttct
     3601 catagacgag aatttatata ttatgatata atacggtaga aaaatatgca ggttattaac
     3661 ctgccattaa tgtaaataat tctttgagga gatgtttcca gtgggacgta aatgggcaaa
     3721 tattgttgct aaaaaaacgg ctaaagacgg tgcaacgtct aaagtatatg caaaatttgg
     3781 tgtagaaatc tatgctgcgg ctaaacaagg tgaaccagac ccggaatcaa actcagcttt
     3841 aaaattcgtt attgaacgtg cgaaacaagc acaggttcca aaacatgtta ttgataaagc
     3901 cattgataaa gccaaaggtg gcggagatga aacgttcgtg caagggcgtt atgaaggctt
     3961 tggacccaat ggttcaatgg ttatcgctga aacgttgacg tctaatgtta accgtacgat
     4021 tgctaatatc cgcacaattt ttaataaaaa aggcgggaat atcggagctg caggtgctgt
     4081 cagctatatg tttgacaata ctggagtgat tgtatttaaa ggaacagacc ctgaccatat
     4141 ttttgaaatt ttgcttgatg ctgaagttga tgttcgtgat gtaaccgaag aagaaggaaa
     4201 catcgttatt tatactgaag ctacagacct gcacaaagga attgcagcgc taaaagccgc
     4261 tggaattact gaattttcaa caacagaatt agaaatgatt gctcaatcag acgttgaact
     4321 ttcaccagaa gatttagaaa tctttgaagg acttgttgat gcccttgaag atgatgatga
     4381 tgtgcaaaaa gtatatcata acgttgcaaa cctctaatta taaattaaac aaatctgtct
     4441 ctatggcaga tttgtttaat ttataaagct gttataaaaa agtctatctg gccagatata
     4501 taagttttta aatttatgtt tattagttgc cacttgatct gacacatagc cttgaaaggt
     4561 tgagagctac cggttttgat atggtgttga atccttatat aaaacatgag gtaattctca
     4621 tgcttcatac gacgaatccc gtcagcaaga taagcaaaag ccagcaatat cgggctactt
     4681 acaatctccc tgtgctcttt aagatgccgc gcctcataaa ttccgcttgc gctcatgatg
     4741 gctcatctgg cgctctacgc gtcgcctgac tacaggtgtg actccaccag cgcgctacag
     4801 accatagtgc gagaaccgtg gccgattact tcgatgcttt tgatgtggag ctatttttaa
     4861 cagataacgt ataccacact caaaatactc ccccagatca atgctctcct ctgaacacct
     4921 ctttcctatg ccattccaca aaccgctcac ccggataatt ttctttaacc gggggcaacg
     4981 cgatctcttt ccccgcaaaa tcccagaaca accgctgtac cactccgcca ccattcaccg
     5041 cgtcggaaac cactacgcgc atattttcat ccaggccaat cgaaccacga tcgaacgctt
     5101 tatgatggat tgcgcacaac gccaggccat taggtacttc acaaggacca tgatgctgct
     5161 tccatctgat atgggctgct tcaagggcta taggggcgtt gtcgtggcgc atattgaagc
     5221 cgcagaccgc acattgataa ttgtaagctc gtagcaccgc ctggcgaaac ttcggatcgc
     5281 gttgacggaa agaggtgcga atatcaaaac ccatctcgtc agcgatgtct tcctgaatac
     5341 tggtcggaaa atgcgcctca aggatctgct gcgccagcgt gtcgattagc ttacgttttt
     5401 ttgttaccag cgcgaaattg acggcatcaa acccaccagc aacattatat tcaatgagtt
     5461 cacgtttagg tggctggcgg ctaccgctgg ttgagcagaa ttccgcgttt tgcaattccc
     5521 agaaaccatc gcccttcaga cgccagaacg gcatatccgg gcgctgttca cggcgctgtg
     5581 gcccatagcg ctccagcaaa tccagcaatt gctcatgaat ttcagaacca taatcaaaca
     5641 gacgatcgtg accctgccga tagtgcgaga gaacatataa cagcaataac ggcttatgcg
     5701 gcgctcgctg ttcgcctttg cgccaaatag taatatttga tatcgcttgc tttagggttt
     5761 tgtcagaggt cattacattg aagaattcat gagcacatag ttgcgatgat gctctcccag
     5821 tggatcatgg tgcgggcggc gagctgtgca tcaccctttc gcgtcctcaa gataacgggc
     5881 ggcaagcatt tcagcggatt cgatgcctgc gataccactg actgctttgt cgtagagcca
     5941 accgatgatg gactggaaag agcgcgggtg gtgggatgga gggaggtcgt cagcgctttc
     6001 gtcgtcctcg tcttcgtagt tttggtattc gttattcagc tccatatcac tcctttgtag
     6061 gcaggcaggt aaaaagaagg ccggaaccat cgtaaagacg gttccggccg gaggttcaat
     6121 gggatgatat ggggttgaaa agatttgtag ctacaaatca tctccttaca gattaaaaca
     6181 aatggcgagt agcccctccg tataataaac ttaacttatt gattaaaatc aaactaatat
     6241 caatttcaaa tttaattaaa ttcataattc aattattgtt atctgttttt tcaaaataac
     6301 aaaaagttat aataactttc agccattcac tgttctaatg caaggagctt gctttgagtc
     6361 agtccgaata cgcatccatt ctaaagtgta ccccatggct agctaaattc ctcacccgca
     6421 gaggattgaa gcaaccagac catcgtccgt tatatgaata ccacgcaacg agtgaagaat
     6481 atgatgaatt gaaacggctg ctgcgagcta taggggtacc cgatggttat aaaagtgata
     6541 aagggtacgc agcctgtttc acattgttct gctcagagtg gtatcgaaga gattatgaaa
     6601 gagagtatgg atgggcatgg gagccaattt acaagacgat aggtatctca gcatcttcct
     6661 cgaaaatggg gaaaattatc cctaaaggcc tggatggtta ctgggggcgt ccagtgcggt
     6721 tttatgacac agaaaggcgg aatttcttag gctccttatt cagtgaaggc ggtctacctt
     6781 tcaggttgct aaaggaatct aatagccgtt ttcagtcgat gttttctctc attctaaatc
     6841 aatacgatca ggctaaatct tctaacattt ccacgttcgc gttagtccat gcagcggtag
     6901 aaaaatcatc cctgccagtc gttttcaaag aggatacttc agttgagctt attagtcgga
     6961 tggctgaaca gttagtatct cttgttcaaa tttatgattt aagtaatcat accgaacccg
     7021 taaaagaact tgaacgtgtt catcctaagt ggcgtgacag tttccctgtc cctctcgatg
     7081 atgatacggg taccagtttc cttaatggac ttttacgaac agcttctact gaatcaaaac
     7141 cccgccttca aaagaataaa accactctct gtcagttttt atggtcagaa aatcatcctg
     7201 aagccctcca ggcactcatt tctctgcctg aagaactgag tttttcaatt gatattgagc
     7261 cttcaacaac gcgcttcgag cttgctatct atgaagatgg taacgaaatc gcaagtctgg
     7321 gacctgcata tgcaacgcta agtaactccc aggcaaaaat aaaagttcgt aagcgcgaga
     7381 ttaaatttta ccgaagaaat cccacggtca gtttgtttat tgtggcgaga gctgggggta
     7441 tgtttttcgg ctccaatctt ttagaaggca gtgaagttgc ggttggcgat gttccattgg
     7501 tttttgtttc tgataaaaat gaatggctgt tacagggaca agcctcttgc agcgtacgtg
     7561 gcagccatgt acttattgtg ctgccaaagg atggctgtct ggcttcagaa catgaggatt
     7621 gtgactctgg cttttcggct ttgggatgcc atgctctgac catcaaaggt cgccaggata
     7681 tcatcattaa aggcgatgaa acgtaccgga taaagatagg aagagatcag attatccata
     7741 ctggattctc tttccagggg aagcgattaa attggacaag ttatccggat gaactcttcc
     7801 tcggtgttcc tggaattact caacattctg agaatctatc aacgcgccat tacaagcgtt
     7861 ttttcaacgg aacatttata gaaaattgtg atgtacaaga aaaaatggga gcacagttta
     7921 tttcggtgcg taacgaaaat gatgaaacgt tactgcgtaa gaaaattggc attctcccca
     7981 atgattttag tctggaaata aaaaatggac aacaggcgaa cgaaggttct gtcattatta
     8041 ctactcagca cccttgtttg tatagcttga aggaaaaaac acttgaagtt ggacggaagc
     8101 ggttgcccga tagtacagaa ataatgatga aggcggaggg cattcctcct gcatcaattt
     8161 cattacaaat aacgccaaac ctcactgcaa acccgattgt tatttggtta ccatttcctg
     8221 cacgaggctg tcttgcgttc gataaagatg agaaacctct cccgaaaaat ttaacgatta
     8281 acgatcttct gggtgccaga gcatatcttt tcggaaaaaa tggtgagcct acgcgatacc
     8341 agcttgaact acgtttacgt tcgcgtagtg gaatgcaggc ctggtatgag tggcactaca
     8401 gtgcgggaga atgtccggta gagcttactt tatatagctt aagggaacat attgataatt
     8461 tactctccct ggaggaagga attgatcaaa cagttgatat gcgcataaaa ggaggtggta
     8521 gttcttttac ctggcagatc cgacgttata aatatagtct ggactatgat cgtggcaggc
     8581 agattcttct cgcaaactca ataagtaatc gtacaggcca gatcccttcg cccgtcatta
     8641 tgttactcag cgaaccggag agaaaagttg tactgctgac gtcaagaatg agcgaaggtg
     8701 taccagttgg tgaatttgaa ctaagttcga taatacaaaa gaatggccca tggctggtgc
     8761 tgccgaaacc aggtgaagaa gcctcatttc gaccttgctt tattgcaggt gagccggtaa
     8821 ttcaaagcga cgcgacagca atacagtctt tacaaaaagc aacgcagctt tttaatcctc
     8881 gttcagatgt caacaccatt atgttagttc tggaacaaat ggcgagcgac ccggcacact
     8941 cgggctggca gttcttacgc aatttatacg atcagttcgg gtatttacct ttggctacct
     9001 ttgaagtatg gcgggcactt gttcagcatc cacaagcgtt ggcgatgtcg ctgttcaaat
     9061 ttgaaatgtc cattgattat ctcagccgta ttgaaagtga gtttcccgtt ttctgggagt
     9121 ttttatccat tacagaagtt aaacgttccg ccacacgttt tcgtgctttt ttgactcata
     9181 aaggtgcacc ggaggaaatg cagataaggt tgctgtacag aatgtatcaa cagctgggca
     9241 caacattccc gacttatgcc agtgaggtgc aattatggtt gagtcaaggg aaattaccac
     9301 cggtttttcc tgagttgacg atgaaaggta ttatccttga gtggtatcag gaacttctac
     9361 gcgaacatgg tgaatctcgc tggccagaat ttggtggccc aggcctttta cgttggtata
     9421 tgtcgcaaca aaatcctgtt atcgatattt cccctgatgc cagctaccgc tattccgtca
     9481 ccttgctccc cgtatttgct gctgctgttg ccagcggtaa aacaacattt gaaagtgttt
     9541 ttgagaataa gcccggcgcc gtatttttct tgagacaggt tagagatttt gactcacgat
     9601 ggtttaacgc cattttccaa tactgtctat tgcgtaatgt tactgaaaaa taaaaaggaa
     9661 taagaatgac tacacgctat ttttcttcgc tgattgaaca atcactgtcg cgttctacgg
     9721 aggcgacgct gagtattatg ggggtgacca acccgaatct tcgcgagcat ctcacgcaac
     9781 aaatggcggc cgattgcggg aaagaaggat cgtttcttgc ctcccccgta tttgaacaga
     9841 catttggctg gaaagagtcc aacagcacaa tgaaagacct tgcaacaaaa caaacgttgc
     9901 taagcaagga ggtggtggac tcgctggata gtgaggaaaa tggtcgttat cgttttggct
     9961 ctgactggaa acctttcacg catcagttag ccagctggca atcattactt gagaaaaaac
    10021 actcagtcgt ggtgaccagc gggacaggct ctggcaaaac ggaatgcttt atggtcccgg
    10081 tactggaaga cctctatcgt gagcttcagg tcaagaacaa aaaaccgttg ataggtgtga
    10141 gagcactttt tctttaccca ctgaatgccc tgattaattc ccagcgcgag cgtttagatg
    10201 cgtggacccg tagttttggt tccggaattc ggtactgtct gtataacggt aacacagaag
    10261 aattgcacgc tttggtcaaa agtgagcagg caaacaggcc taatgaggtt ttgtcacgag
    10321 agaagatgcg tgaagaaccc gcccccattt tagtgaccaa cggtaccatg ctggaataca
    10381 tgatggttcg tcaggttgat gcaccgatta ttcagaaatc aaaagctgaa aaatcattac
    10441 gctggatagt tctggatgaa gcccatacct acgttggttc tcaggccgct gagttggctc
    10501 tacagctccg tcgcgtcatg acggcatttg gcgtcacgcc tgatgatgtt cgctttgtgg
    10561 cgacgtcggc caccattgcc ggaagtgatg ctgaaaagca gctgaaaaaa ttcttgtctg
    10621 agctgtcagg agtgccacag gaacgtattg atgttctggg cggaagccgc gttattcctg
    10681 agctcgaacc ctgcaaacaa tattctctgt cactggatga gattgagcat atccctgatt
    10741 cggagagtga agggatcagt ccggagcgtt atagtgcgtt gacccactct ccggaagcgc
    10801 gctgtttacg cgaaatgctg gttagccaac cccgaccaat gaaacttgat acgctgaccc
    10861 agcgtttgaa cgagctgacc aaacatcagt acacgcagca ggatgtttta cgctggatcg
    10921 atctttgctc tggcacactc cctaatgcaa aggatcctgc atttctgaaa gtcagagcac
    10981 atattttcca gcgaaacacc cagggcatct ggacatgtgt ggataagaac tgtgcagcta
    11041 aaaaaaatac cgcgctggaa aaaaactggt cttttggcaa tgtgtatgta aatcagcggc
    11101 aaaactgcga gtgcggcagt cccgtttttg aactggcatt ctgcaatgag tgtaatgaac
    11161 cgcatcttct tgcacgggat aaaaaaggca aactcgtaca gtgggataat aaaggtggag
    11221 atgaattctc cctacaggat gaaatttctg acgattttga aacatccgga gaaaagattc
    11281 agaaggattt tgtattccag tcgccacaaa ttattgctgc ggaatgtaat acggaagctg
    11341 gctatattat gcagcggctc gatcgtcaga cccgcagtat cggcgtggtg aacccggaca
    11401 gtattccgct ggcaattaat gatatcgaac aaatctgtag tgccagcaat tgtggctata
    11461 aaggcggaaa gggtaaacag cccttccgaa gggcgttact gggcgggcct ttttatgtca
    11521 ccaatattgt gcctacggtg ctggagtatt gtcaggactt cactagtgat gaaggtaaag
    11581 atggtgtcgg cccgctctct ttgcctggtc gaggtcgtcg cctgattacc tttaccgaca
    11641 gtcgtcaggg gacggcgcga atggcagtac gtatgcagca ggaagcagag cgcagccgat
    11701 tacgtggtag cgtagtagaa attcttggct ggcaccaacg aaaacagcca acgagtgctc
    11761 cgaatgacca ggctgacgtg atgaaactgg ttgcaagggt gacacaatac cgtgaagaag
    11821 cccgggagta tcgcgagtgg ggaatgcccg aggaagcaaa actttctgaa gctcaggccg
    11881 aacgccttga acaggcaatc cagacggcga cggggggaaa ggctgcaacc attttagttt
    11941 gccgaacctg gacggaaatg gtcaatgatc tgaaagagaa agccgatata cagggaccaa
    12001 ttttacaata taaccattat ctgaagcctg aaattttcac cgaaaatggc ggccctttga
    12061 aactcgccga aatgctgctt ttccgtgagt ttatgcgacg cccgaaacga accaacagcc
    12121 tggaaaccca ggggctggtt caggttggct atcaggggct ggagaaggca ggctcacagt
    12181 gttcctactc actggcaggc taaaggctta acccttgatg actggcgcga ttttctgaag
    12241 gtgacgctgg atttctatgt cagagaaagc aactacatcc aactggatga cgatctaaga
    12301 aactggatcg gtagccgttt ctcttccaaa tttgtccgca acccagattc gaaagagcca
    12361 gatgacaacc aggttaaacg ctggccgcaa attcgccacg gtaatgtgac tcagcgcctg
    12421 gtcaagctgt tgattttagg ggccaaattt aacaccgtaa atacggtaac tattgatatt
    12481 gttaacgcct ggctgaaaga agcctggctc cagctaacag gatctctggc ggtattgaag
    12541 cctgatggaa accgttttta tttaccgaaa gagcatctga cattctctct ggtgcaaaaa
    12601 gcacgcattt gtccagtgac caataaatta ctggcgacaa ccttcaaagg tctgaccccc
    12661 tatttgccca tgcatatcca gttcgagcga ctgacgagtg cacagtacga cgcgtttttg
    12721 gctcaggaag tcacgctgcc agcgatctgg gaacacgatc gctctcagga tgattatgtc
    12781 gacgggttaa caaaagtgcg tgactgggta agccaggatc cgcaagtgct accattacgc
    12841 tcgcaaaacc tctggacgga cattaacgat cgcgtggtag aaggtggatt ttactaccgc
    12901 accgcagaac actcggcaca gcaatcgtcg gagcgcctgc aaagctacga aagaatgttt
    12961 aaaaacgggc agcttaacgt ccttaactgc tcaaccacga tggaaatggg tgtggatatt
    13021 ggcggtattt ctgcagtggt gatgaacaac gttcctccgc atccggccaa ctatttacag
    13081 cgagccgggc gtgccgggcg tagtaaagag tcacgcgcta tttcgtacac cttgtgcaaa
    13141 gggaacccgc acgatcagca ggtttttgct aatcccctct ggccgtttga gacggtgatc
    13201 ccggctccaa tggtggcaat gaactcagag cgtctggtgc agcgtcacgt caattccctg
    13261 ttactgtcag aatacttatg ccatgtggtc ggtgaaaccg aaaaagagcg taccagcctt
    13321 aatagccagt ggttctttgg cgaagagctc gaccagtcgg tatgcaatcg ttttaaagcc
    13381 tggctcgaac gtccgacgct gagcattgat aacgcgctgg agcgtctggt taaagggacg
    13441 gcattgcacg gcgttacggc agaaaaactg cgggataaaa cgcaggaggc tattgccgtc
    13501 ttacagacac gctggctggg gatcttccgc gatctcgtga aacaggaaag tgaatcgcag
    13561 cccaatacgc cgtaccgcag gcgactggaa ctggagaaaa aacggcattg tggtgaatac
    13621 ctgttacgcg atctggcggc ccgaactttc ctacccggat atggcttccc aacggatgtt
    13681 gtcacttttg ataacttcac catggaagat tatatccgcg agaaaacgca caaaagccgt
    13741 gataagaatg accgggagga taacgtttcg cgttataaag ggctgccttc gcgcaacctt
    13801 tccgttgcga tccgtgagta tgcgccgggc gcggagatta tccttgatgg tcgggtattc
    13861 cgctcggccg gtgtttcgct gcactggcat aaccttaacg ccgatactaa cgaagcccag
    13921 cgtctggaca gcgcctggcg ttgccataaa tgcggtactt taggctatga ggaaggtatt
    13981 ggtggctcgg gggatttatt ctgtaccaat agcgcgtgcg gggagcggat cacgctggat
    14041 aaccgacgtc aggtattaca gcccgccggt tttgtcaccg atgcccatac tcccgttacg
    14101 aacaacattg aaacaatgaa attcatcccg gtggtgcctg cctgggtgtt tgtgaaagca
    14161 gaacgcgtgc cactgccaaa cccgctgatg ggttttatgg cgtcaggcgc ggatggtcat
    14221 gttttccagc agagcatggg cgaaggtgga cacggttatg cgctgtgcct gagctgcggc
    14281 cgggcggagt caatgctcaa tgccaccgat acgccgaaat cgatggaagc gcattatcct
    14341 ccgcgccccg gtaaatctga tcgcgacagc cagaatcagc ggattatctg ccctggctcc
    14401 acggcgctga ataagaatgt cacgctgggt gcgctggcgc gcaccgatgt gtttgaactc
    14461 attttgcgcc gtccgcaaaa cggggagtat atccccgata attctgatga aggccgtatt
    14521 gtggccatga cgctggcggt tgcactacgt cgagcgctgg ccagcgtgct gggggtatcg
    14581 gcgacagaac tgggctatgc ggtgcgtccg gtcagactgg ataatgagca atcggtcctg
    14641 gcggtgcagc tttacgacat tatcagcggc ggtgcggggt ttgcttccag tgcgccattg
    14701 catattgaag cggtcctcaa agggatggtg aaacagctgg gatgccgcca ctgtgatacc
    14761 gcctgtagcg aatgtctgct cgattcgcag acccgccacg atcacgatca gctggatcgt
    14821 aaagccgcgc aggcctggct gggggaggat ttcagtcact atatcggttt gccggaggcg
    14881 gaaaaattct ccctggccga cgcgcagtat tgcccaggca gcattgagga tgctatccgt
    14941 cgtgccatta acgacggggc gcgcaaactc acgttgtgga tgaatgggcc gcttaacgag
    15001 tgggatttgt atgcccgcca gttccgaacg gcgatccaga actatcggct gaaagatgag
    15061 gttgaggtta cgctggttgt gcccggtcat attgaagatc cggagctttt acaggagatt
    15121 gcgcagtttg ccgccattgg tatgcagctt tgccagtctg agctgaatac ggatacgccg
    15181 gttgtcgcac aggtagcatt caacgatcgc ctgatgatgt tgatttctcg cagcccagag
    15241 gccaccatcc ccggcccgaa ctggcatctg aatagccaga tggttattcg cagccatgcg
    15301 tttgagccga taacgcttag taaagcagag ctattatccg atgccgcagg tagcagaggc
    15361 ctggtcaacg atattgagat ccataagcag cttaatggcc cggtttctca atttggtcag
    15421 cgtttctggg gcgtgttaac cggggcgcag gaagatattc agacgctgct gaaggaaaac
    15481 caggtgacgc gcattcacta tagcgatcgt tatctgcaaa acccggtggc gctggcgtta
    15541 ttaggcgggc tgttaaaacc gctgaaatcg atcctggcgc aggatgcgca agtgacgatt
    15601 gatacgctgt ttaagagtaa agagcggcca ggcaacaagc cgttccatga ctggatgagt
    15661 gaagcggatt ttcaggattt tgccgaccag tggtttgcgg catctatggg cagagccgtc
    15721 gtggttaaca ccgttggctc gccgcgtgat attccacacc atcgtaaact gatggtgacc
    15781 ttcagtaatg gtcaggcgct gaagatccgt tttgaccaag ggatgggata ctggcgcatc
    15841 gtctttgcgc gagcgtatcg cgattttgat tttaacgatg atgtggcttt ccagctcggg
    15901 aatatggcaa aagcctgcgt tgaaggtcag gtggtcaaca gcgaggaaag ttgggcaacc
    15961 gatgtgctgg tgcaggtgat agtcccttaa tgcgaaaccg ctcccgatta aacatcggga
    16021 gcggctaaca tcaggcggtg gtgcgcttgc cggtaatcat gtcgataatg accctggcac
    16081 aaattcagta cagtgctaaa tcagagagct tcgtctttcc ggagacttcg gataaattca
    16141 gccggagtca tgtcatttaa tgatgaatgc gttctctcat gattgtattc cctgcgccag
    16201 ttgtcgggtt tttcctgcgc atcttccagt gacaggaacc agtgaatgtt caggcattca
    16261 tcccgcagac tgccgttaaa tggttcaata aacgggttat ctgtcggctt tccggggcgc
    16321 gagaagtcca ttgtgacgcc gtgttcatac gcccatttat ccagactttt tgagataaac
    16381 tcgctgccgt tatccgtctg gattcgtacc ggcagccgct tatccggcac ccgcagtgcc
    16441 tccattattc tgaccacatc ctcgcctttt aacgattttc cggcatggat cgccaggcat
    16501 tcccgactaa aattatccac tacagccagc gcccgaaaac gccgcccgtt aaacagatta
    16561 tctgacacaa aatccatact ccggcactga tcgacatgcg tcagaaccgg gcgctgatac
    16621 agtaagcctc ccgcaaaaat gtaaccgcct ggcgcttctg agccggcctc agaacttttg
    16681 cttcagtacc tcctgcagca tctccttgtc gagactcagc tcagcgacca gcttcttcag
    16741 ccgctgattc tcatcctcca gttgccgcag acgccgctgt tccgtcacgc ccggcccggc
    16801 aaattttttc ttccagttgt aaaatgtggc ctcagaaatt cccatctttc tgcagacttc
    16861 cccgacgcgg gtgccggttt cagcctgttt cagggcaaat gcagtctgtt cttcggtata
    16921 acgggtcttt ttcatggcaa tgcgcctctc tgtgagatgg aagaaagacc ggaaacttca
    16981 gtttagactg gcactgttta cagggggaag gtcaggggaa ggtcatcaac cagcttccca
    17041 ccatcaccac aaaccagaat aattccctga aaaaagatgc gctgaatgtt atgtttttca
    17101 tcatctttcc actgtcagaa tccaccgctg acaccggcac caacaccggt cggcttcacg
    17161 cggcgaattt tacttcacct tccgcgccgc ctcatcctca ggacgaagcc gtgcgggtga
    17221 agcggtaaaa cagattcggt tcactgacta tccacagcgt gtcccggtca tctgaggcta
    17281 tcccctccgc ctgcgggata tcccttcgca ggccacagtg tccccggcgc agcgacatca
    17341 ccttcctccc gccgtccaga tccgacacca cgaccacggc agattcatgg gaaagtacat
    17401 acaggagccc gttgttccgg tcataatgca gaccggagat atccttcagg aaccatggca
    17461 gggacgcccg gtgtgtcagc gagtcactca ccgacagcgc atcagggctc cggtccgtca
    17521 cgtaaagccg cagcggtttt ttctcctgcg ccaccatcag ggcatgctct ccccgtcccc
    17581 aggcaaggcc ttcaaaaccg gcattgtcgc tgtgcctgtt cacatccagc gtcaggctgt
    17641 atgttgccgg cgggaggacg gtcgtgctgc tgtcaatgca gtgggtggtg agcgtccgct
    17701 cccgctcccg ggacagggca tagcggttcc cgccgaggta ttcgatggcc tcaaaatcgt
    17761 ggtcgccgtc tgacggtatc acccgcagca cgttcccttc cgtgtccagc tccaccaccg
    17821 aggaggggtg gtcggtcacg gcaaacagcg ttctgctgtc cgggttccat gtcaggccgg
    17881 agaggccgcc gtgtatcccg gtaatttctt tttctgccgt gagctgccat tctgtttcct
    17941 gcgggtacca ggactccggg aaacacaggg tgagcacgcc ggccgccatc aggagaatgg
    18001 cggtcagcag tgcagctttc tggttacata aatatctgaa catcgtggtg gtgaaagtta
    18061 tgttttctgt tacaggggag accggacttc acatcatgcc ccacggcaga taagccagag
    18121 catggccaag acgccggtca gaaagccgga gataaagacg ctggtcagca gcaggagaat
    18181 cagcgcgcgg agcgggggga tatctccggc ctgtatggtg cctttatcat cagtcggcat
    18241 cagggttacc ggccagcagt ttccggacca ccgcggcata acggctcctg aaatcttcga
    18301 cggagaatgc accgaaggcg gcattgttga tatggtaacg gccacggaca tacacggaag
    18361 gcgtccccct cacgccatat tccttaaaca accgttcctg taatgccacc atgtcattca
    18421 cggcgggact ttttatactt ctgtcatact ccccgcgact gataccggta gcagacataa
    18481 acacccgacg gacatcgtcc ggggaatgca ggcgtttctc caccatgtcg gccgtgaaga
    18541 aggccttctc gaccacgtca gtttccttca tcatcatggc cagcgcccag gcctgtgtca
    18601 gctcatggcc gagggggccc agcaggctga catggtactt gatcatccgg tcaccgtgcg
    18661 gcagtacgtg ccggatggcc cgggccacgc ccatcgtctg tgagaacgca tagcagggcg
    18721 gacagtaaaa gaaaaatagt tccacctcgg cgggggcatc agccaccaag ggagttatga
    18781 actcccactc ctgcgcaatc acaggacggg cgcggccagg taaaaaaaaa agaaaataat
    18841 attcccctca ggaaaaacag ctcccgggca taattcatcg tcacggaaac actccatgga
    18901 taacagatat acagaatgaa aggccgctta acggtaccgc ctgacagcag cagtaaatct
    18961 taattcatcc ggcacggtca ttaagccggc agccggaata ttccggtcat gagttttcca
    19021 gaataaaaag cactgacaca caaaagacca ttgccattaa tatgacgacg gccagacagg
    19081 cgtaataaac gaatttcatg aacatgataa aataactttc agtgatactt atccagcttc
    19141 cgacccacat tccgggccgc tctcctccag tgaatgacac cggttcaggt ctgtatacag
    19201 tgtcaccatc cccagaagca tcagggttgg caacagggtg gcatcattcc tgacgccgag
    19261 gcgcctgaaa gccaggcctt tctgggctga aatggttttg acgctgcgaa aacagagggc
    19321 agcaatctgc ccgcagttat agccctgcag cagcagtcgg ataacccgca gttcagccgg
    19381 actcagtccg ccgtcgctgt taaattcgat acaaagccga tcgtaccata tccggctgat
    19441 gtccccgtct tccgggaaag cggtcaaagc agacgccata atccgggcgc tccctttccg
    19501 gcatttactt tctcaagcac cccgacagca cggagttgct caagatatga gcggacctgg
    19561 tagatactga gtccggcagc atcagcaata tcgcggattt taacaggcgc gttgtccgta
    19621 ctctgacgct cccggatgat ggagatgatg tttgtaatga tggattcacc cataaacggc
    19681 cccactcttc aaggttaaaa taaatgtatt taccactacc acaaaataat actaatccat
    19741 tctatagcaa cctcattacg atatggtcaa accaagacga aaagtaaaaa tatatgaata
    19801 ttttgatggt tcatttatgc gtat
//
LOCUS       DAJVKX010000081        19280 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.081, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000081 DAJVKX010000000
VERSION     DAJVKX010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 19280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19280
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.081"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            4..2592
                     /locus_tag="OPY25_002944"
     CDS             4..2592
                     /locus_tag="OPY25_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HCS0928508.1"
                     /translation="MNIVLSNQRFEEAERDAKNLMYQCSLATEIHHNDIFPEVSRHLS
                     VGPSNCTPTLNGEKHRLFLQSSDIDEKSFRRDSFILNHKNEISLLSTDNPSDYSTLQL
                     LTRKSFPLYPTHAGFYWSEPEYINGKGWHASVAVADQQGVFFGVMVKLPDLISKSHLP
                     LDDSIRVWLDQNNHLLPFSYIPQKIRTQLENVTLHDGWQQIPGFLILRTTLHGPGWSL
                     VTLYPYGNLHNRILKTILQQIPFTLTALVLMTSAFCWLLHRSLAKPLWRFVDIINKTA
                     TAPLSTRLPAQRLDELDSIAGAFNQLLDTLQVQYDNLENKVAERTQALNEAKKRAEQA
                     NKRKSIHLTVISHELRTPMNGVLGAIELLQTTPLNIEQQGLADTARNCTLSLLAIINN
                     LLDFSRIESGHFTLHMEETALLPLLDQAMQTIQGPAQSKKLSLRTFVGQHVPLYFHTD
                     SIRLRQILVNLLGNAVKFTETGGIRLTVKRHEEQLIFLVSDSGKGIEIQQQSQIFTAF
                     YQADTNSQGTGIGLTIASSLAKMMGGNLTLKSVPGVGTCVSLVLPLQEYQPPQQIKGT
                     LSAPFCLHRQLACWGIRGEPPHQQNALLNAELLYFPGKLYDLAQQLILCTPNIPIINN
                     LLPPWQLQILLVDDADINRDIIGKMLVSLGQHVTIAASSNEALTLSQQQRFDLVLIDI
                     RMPEIDGIECVQLWHDEPNNLDPDCMFVALSASVATEDIHRCKKNGIHHYITKPVTLA
                     TLARYISIAAEYQLLRNIELQEQDPSRCSALLATDDMVINSKIFQSLDLLLADIENAV
                     SAGKKIDQLIHTLKGCLGQIGQTELVCYVIDIENRVKMGKIIALEELTDLRQKIRMIF
                     KNYTIT"
     gene            2623..3261
                     /locus_tag="OPY25_002945"
     CDS             2623..3261
                     /locus_tag="OPY25_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system response regulator"
                     /protein_id="HCS0928509.1"
                     /translation="MKEYKILLVDDHEIIINGIMNALLPWPHFKIVEHVKNGLEVYNA
                     CCAYEPDILILDLSLPGINGLDIIPQLHQRWPAMNILVYTAYQQEYMTIKTLAAGANG
                     YVLKSSSQQVLLAALQTVAVNKRYIDPTLNREAILAELNADTTNHQLLTLRERQVLKL
                     IDEGYTNHGISEKLHISIKTVETHRMNMMRKLQVHKVTELLNCARRMRLIEY"
     gene            3440..4168
                     /locus_tag="OPY25_002946"
     CDS             3440..4168
                     /locus_tag="OPY25_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCS0928510.1"
                     /translation="MSYSIGEFARLCGINAATLRAWQRRYGLLKPQRTDGGHRLYSDD
                     DIRQALSILDWVRKGVPISQVKPLLSRPVIRLGDNWITIQETMLQHLHEGRIDALRQL
                     IYDCGREYPRAELVTHLLRPLRSKVSAHLPAVMTLREILDGIIIAYTSFCLEGDRKAP
                     GNNAFISGWHLSDHCEIWLEALTRTGQELRLNVLPSPPAVLAPELFAQRKWFLVTTGK
                     LTAGQKKQLAQWRNVVASLEVITL"
     gene            4340..5299
                     /locus_tag="OPY25_002947"
     CDS             4340..5299
                     /locus_tag="OPY25_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="HCS0928511.1"
                     /translation="MNNKPVVGISGCLTGAAVRFDGGHKRMDFVMNSLAPWVAYKPIC
                     PEVAIGLPVPRPALRLIQTTCGDIRMRYSHAPHDDVTERMNAFADRFLPTIGELAGFI
                     VCAKSPSCGMERVRLYDEKGNRGRKAGTGLFTAAMMDKYPWLPIEEDGRLHDPVLREN
                     FIARIFALHELNALRAQGLSRHSLLAFHSRYKLQLLAHHQAGYREIGPFVARLHEWDD
                     LDAFFVRYREKLMAILRHPASRKNHTNVLMHIQGYFHRALNSRQRAELREVILGYRAG
                     RLPILAPLTLLKHYLAEHPDDYLRSQNYFEPYPDTLGLRLAIT"
     gene            complement(5395..5607)
                     /gene="fumD"
                     /locus_tag="OPY25_002948"
     CDS             complement(5395..5607)
                     /gene="fumD"
                     /locus_tag="OPY25_002948"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase FumD"
                     /protein_id="HCS0928512.1"
                     /translation="MTKPTKDDELYREMCRVVGKVVLEMRDLGQEPKYIVIAGVLRTA
                     LANQRIQRSALEKQAMETVINALARS"
     gene            complement(5705..6325)
                     /gene="ttrR"
                     /locus_tag="OPY25_002949"
     CDS             complement(5705..6325)
                     /gene="ttrR"
                     /locus_tag="OPY25_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460352.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TtrR"
                     /protein_id="HCS0928513.1"
                     /translation="MATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLY
                     QAGVVLLDMRMPVLDGQGVHDALRQCGSTLAVVFLTGHGDVPMAVEQMKRGAVDFLQK
                     PVSVKPLQAALERALTVSSAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAM
                     NIAVRTVEVHRARVMEKMQAGSLAELIRRFEKMASPETRIRTTYEP"
     gene            complement(6300..8078)
                     /gene="ttrS"
                     /locus_tag="OPY25_002950"
     CDS             complement(6300..8078)
                     /gene="ttrS"
                     /locus_tag="OPY25_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     TtrS"
                     /protein_id="HCS0928514.1"
                     /translation="MRGKTVRRLAVLAAVGLLCHGAWAGTWNIGILAMRGEASTRSHW
                     QPLAKTLSQQLPGETFHIQPLDLHQMQEAVNQGTVQFVITNPAQFVQLNSHAPLRWLA
                     SLRSTRDGKAVSNVIGSVILTRRDSGITTAHDLIGKTVGAIDAQAFGGYLLGYKALSD
                     AGLRPERDFHLRFTGFPGDALIYMLREKAVQAAIVPVCLLENMDQEGLINKKDFIALL
                     SRPTPLPCLTSTPLYPDWSFAALPAVSDALADRVTRALFNAPAAASFHWGAPASTSQV
                     EALLRDVRQHPQQRRLWLDVKSWLIQHQLMVGGVILAFLLLTLNYIWVMLLVRRRGKQ
                     LERNSVVLHQHERALETARQMSVLGEMTSGFAHELNQPLSAIRHYAQGCLIRLRAADE
                     QHPLLPALEQIDQQAQRGADTLRNLRHWVSQAQGNPVLTEAWKAIAIREAIDHVWQLL
                     RMAQQFPTVTLHTEVSAALRVTLPSVLLEQVLANIILNAAQAGATHLWVVAERTENGI
                     SIVLQDNAGGIDEALLRQAFQPFMTTRKEGMGLGLAICQRLVRYGRGDISIRNQTAPD
                     GLSGTVVTIHFLHEHGGRDGDNSSTG"
     gene            8242..8994
                     /gene="ttrB"
                     /locus_tag="OPY25_002951"
     CDS             8242..8994
                     /gene="ttrB"
                     /locus_tag="OPY25_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetrathionate reductase subunit TtrB"
                     /protein_id="HCS0928515.1"
                     /translation="MWTGVNMDSSKRQFLQQLGVLTAGASLVPLAEAKFPFSPERHEG
                     SPRHRYAMLIDLRRCIGCQSCTVSCTIENQTPQGAFRTTVNQYQVQREGSQEVTNVLL
                     PRLCNHCDNPPCVPVCPVQATFQREDGIVVVDNKRCVGCAYCVQACPYDARFINHETQ
                     TADKCTFCVHRLEAGLLPACVESCVGGARIIGDIKDPHSRIATMLHQHRDAIKVLKPE
                     NGTSPHVFYLGLDDAFVTPLMGRAQPALWQEV"
     gene            8995..10017
                     /gene="ttrC"
                     /locus_tag="OPY25_002952"
     CDS             8995..10017
                     /gene="ttrC"
                     /locus_tag="OPY25_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetrathionate reductase subunit TtrC"
                     /protein_id="HCS0928516.1"
                     /translation="MTHSLIIEEVLAHPQDISWLPWAVQYFFFIGIAACAALFACYLH
                     WRKKDAATEENRALLIAITCAITAPLALTADLHQTARVWHFYAWPTPWSWMPWGALFL
                     PLFTGFLALWFLAQQIKRLFNKSYNVTKWLALASALCAVGLLIYTGREVSVVLARPIW
                     FSYAFPVAMFLSALQAFFALMIVAARRDSVRLPKILWGQLWTLAALGLVVAMWVSGDT
                     LSGTAIRQWITVALSAKYYAVGWLALWVFTLLFCSLALRHPLSELRRVLLVLSALALC
                     WLMRWTLLIQVQTVPKFNAQFNPYTLPGGTDGWLAILGTFGLWIALLISIRETLNGLT
                     RRLQHG"
     gene            10010..13072
                     /gene="ttrA"
                     /locus_tag="OPY25_002953"
     CDS             10010..13072
                     /gene="ttrA"
                     /locus_tag="OPY25_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetrathionate reductase subunit TtrA"
                     /protein_id="HCS0928517.1"
                     /translation="MANLTRRQWLKVGLAVGGMVTFGLSYRDVAKRAIDGLLNGTSGK
                     VTRDRIFGNALIPEAQAQTHWQQNPQQTIAMTQCFGCWTQCGIRARVNADGKVIRIAG
                     NPYHPLSQEHPIDSSVPFSEAMEQLAGESGLDARSTACARGATLLESLYSPLRLLEPM
                     KRVGKRGEGKWQRISFEQLIEEVVEGGDLFGEGHVDGLRAIHAPDTPIDAKHPSFGPK
                     TNQLLVTNTSDEGRDAFLRRFALNSFGSKNFGAHGAYCGLAYRAGSGALMGDLDKNPH
                     VKPDWENVEFALFMGTSPAQSGNPFKRQARQLASARLRENFQYVVVAPALPLSTVLAD
                     PRGRWQPVMPGSDSALAMGMIRWIMDNQRYNADYLAIPGVQAMQQAGEQSWTNATHLV
                     IADELPTLAGQHLTLRHLTPDGEETPVVLNTDGELVDASTCRQARLFVTQYVTLADGQ
                     RVTVKSGLQRLKEAAEKLSLAQYSEQCGVPEAQIIALAETFISHGRKAAVISHGGMMA
                     GNGFYNTWSVMMLNALIGNLSLSGGVFVGGGKFNGVSDGPRYNMNSFAGKVKPSGLSI
                     ARSKTAYKASEEYRDKIAGGQSPYPAKAPWYPFVAGQLTELLTSALEGYPYPLKAWIS
                     NMSNPFYGVPGLRAVAEEKLKDPRRLPLFIAIDAFMNETTALADYIVPDTHNFESWGF
                     TAPWGGVASKATTARWPVVAPATHRTADGQPVSMEAFCIAVAKRLHLPGFGDRAITDP
                     QGNTFPLNRAEDFYLRVAANIAFMGKTPVALANQEDISLTGVSRILPAIQHTLKADEV
                     GRVAFIYSRGGRFAPEDSGYTEQRLGNAWKKPLQIWNADVAAHRHAITGERFSGCPVW
                     YPARLSDGRAIDDQFPIGQWPLKLISFKSNTMSSSTAVIPRLHHVKPANLVALNPQDG
                     ERYGLQHGDRVRIITPGGQVVAQISLLNGVMPGVIAIEHGYGHREMGATQHSLDGVPM
                     PYDPQIRAGINLNDLGFADPTRTITNTWLDWVSGAAVRQGLPAKIERI"
     gene            13395..14621
                     /locus_tag="OPY25_002954"
     CDS             13395..14621
                     /locus_tag="OPY25_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCS0928518.1"
                     /translation="MFKEERRHAIINLLIKDNSVSVSKLSDLYKVSQETIRSDLRYFQ
                     KSGMLQRCYGGGILNRDALSKLITENKIDISSTIATPIHQDAKLHRENTKKAGKVCVL
                     GSFNIDVSATVPWFPQSGESILASQFGFYPGGKGANQALAANNAGAAAHFIFKVGKDQ
                     FSAFAMNHIIQSGTTSYSAYQTDKAPTGSALIYVSAVDGDNIIAIYPGANMMLTTQEI
                     NEQHRYIAESDVMLMQLETNIEALTEFIRLGKQENKMIMLNPAPYTKQVTHLLSDIDI
                     ITPNETEASFLSGVTITDINDAKKAGNIILQSGVKKVIITLGARGSLLCEHARTLYIP
                     AWSAVVKDAAGAGDAFNGALAAALARQADMVAAIQYASAFASLAVEQVGASSMPQHLQ
                     VLHRMRTQSNKVIHIN"
     gene            14633..15370
                     /locus_tag="OPY25_002955"
     CDS             14633..15370
                     /locus_tag="OPY25_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0928519.1"
                     /translation="MKILFIGESWHIHMIHSKGFDSFTSSKYEEGADYLLSCLRQGNI
                     DVDYMPAHIVQTRFPQTAEALACYDAIVISDIGSNTFLLQNRTFYNMDIIPDALQLIA
                     DYVAEGGGLLMIGGYLSFTGIEAKANYKNTVLAEVLPVDMLDVDDRVELPQGCKAVNT
                     AVKHVITQPFSEWPPLLGYNKLIAKENSQVLAEINGDPLLVMGTYHKGKVCCFASDCS
                     PHWGSPQFLQWEHYATFWCNVLHTIKK"
     gene            15429..16117
                     /locus_tag="OPY25_002956"
                     /pseudo
     CDS             15429..16117
                     /locus_tag="OPY25_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            16139..17482
                     /locus_tag="OPY25_002957"
     CDS             16139..17482
                     /locus_tag="OPY25_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCS0928520.1"
                     /translation="MKKVKKLSLTDLVLYGLVFMVPIAPVSLYGVVYNLSHGMVALVY
                     IIGAIAMFFTAYSYSTLSQHISSSGSAYAYAGVCINPAVGFLTGWILLLDYLLFPTLV
                     AVLGGVAVHAILPQIPVWVWPLIYVAIGTGVNYLGIQQTAKFDKLLVFIQLGILAIFV
                     LLIIRLMMQDSSQITLSFRPFFDSQWFTPGLIATAISVAALNFLGFDAISTLSEESEG
                     GGRAVSKATLLALVLATVLFIIVVAFAAFATGNVDRFAEGNATNEAFFTIAGNVGGIW
                     LKVAFSIIVAFVCAVGNIITAQTAVSRVLFSMGRDRMLPAFLAHVHTTRKTPDYAILF
                     TGGVTLLLSYLFSGKIESISTLVNFGALFAFFVVNLCVFILFNFRMKAQRRIFAHVIS
                     PIMGMIVIGYVCLNMNIHALILGISWAAIGIAILCYRKAYNQNIAIDLEGKKLLD"
     gene            17884..>19280
                     /gene="pykF"
                     /locus_tag="OPY25_002958"
     CDS             17884..>19280
                     /gene="pykF"
                     /locus_tag="OPY25_002958"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HCS0928521.1"
                     /translation="MKKTKIVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKKAAILLDTKGPEIRTIKLEGGNDVSLKAGQTFTFTTDKSVVGN
                     NEIVAVTYEGFTSDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLDYNNDSRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEVTARQLVLSKGVVSQLVKEINSTDDFYRLGKDVALQSGLAQKGDVVV
                     MVSGALVPSGTTNTAS"
BASE COUNT         4762 a         5059 c         4747 g         4712 t
ORIGIN      
        1 gagatgaata ttgtactaag caatcaacga tttgaagagg ctgaacgtga cgctaaaaat
       61 ttaatgtatc aatgctcatt agcgactgag attcatcata atgatatttt ccctgaggtg
      121 agccggcatc tttctgtcgg tccttcaaat tgcacgccga cgctaaacgg agagaagcat
      181 cgtctctttc tgcagtcctc tgatatcgat gaaaaaagct ttcgtcgcga tagttttatt
      241 cttaaccata aaaatgagat ttcgttatta tctactgata acccttcaga ttattcaact
      301 ctacagcttt taacgcgaaa aagctttcct ttatacccaa cccatgccgg gttttactgg
      361 agtgaaccag aatacataaa cggcaaagga tggcacgctt ccgttgcggt tgccgatcag
      421 caaggcgtat tttttggggt gatggttaaa cttcctgatc tcatttctaa gagccaccta
      481 ccattagatg atagtattcg agtatggctg gatcaaaaca accacttatt gccgttttca
      541 tacatcccgc aaaaaatacg tacacagtta gaaaatgtaa cgctgcatga tggatggcaa
      601 caaattcccg gatttctgat attacgcaca actttgcatg gccccggatg gagtctggtt
      661 acgctgtacc catacggtaa tctacataat cgcatcttaa aaactatcct ccaacaaatc
      721 ccctttacat taacagcatt ggtgttgatg acgtcggctt tttgctggtt actacatcgc
      781 tcactggcca aaccgttatg gcgttttgtc gatatcatta ataaaaccgc aactgcaccg
      841 ctgagcacac gtttaccagc acaacgactg gatgaattag atagtattgc cggtgctttt
      901 aaccaactac ttgataccct acaagtccaa tacgacaatc tggaaaacaa agtcgcagag
      961 cgcacccagg cgctaaatga agcaaaaaaa cgcgctgagc aagctaacaa acgtaaaagc
     1021 attcatctta cggtaataag tcatgagtta cgtactccga tgaatggcgt actcggtgca
     1081 attgaattat tacaaaccac ccctttaaac atagagcagc aaggattagc tgataccgcc
     1141 agaaattgca cactgtcttt gttagctatt attaataatc tgctggattt ttcacgcatc
     1201 gagtctggtc atttcacatt acatatggaa gaaacagcgt tactgccgtt actggaccag
     1261 gcaatgcaaa ccatccaggg gccagcacaa agcaaaaaac tgtcattacg tacttttgtt
     1321 ggtcaacatg tccccctcta ttttcatacc gacagtatcc gtttacggca aattttggtt
     1381 aatttactcg ggaacgcggt aaaatttacc gaaaccggag ggatacgtct gacggtcaag
     1441 cgtcatgagg aacaattaat atttctggtt agcgatagcg gtaaagggat tgaaatacag
     1501 cagcagtctc aaatctttac tgctttttat caagcagaca caaattcgca aggtacagga
     1561 attggactga ctattgcgtc aagcctggct aaaatgatgg gcggtaatct gacactaaaa
     1621 agtgtccccg gggttggaac ctgtgtctcg ctagtattac ccttacaaga ataccaaccg
     1681 cctcaacaaa ttaaagggac actgtcagcg ccgttctgcc tgcatcgcca actggcttgc
     1741 tggggaatac gcggcgaacc accccaccag caaaatgcgc ttctcaacgc tgagcttttg
     1801 tatttccccg gaaaactcta cgacctggcg caacagttaa tattgtgtac accaaatata
     1861 ccaataataa ataatttgtt accaccctgg cagttacaga ttcttttggt tgatgatgcc
     1921 gatattaatc gggatatcat cggcaaaatg cttgtcagcc tgggccaaca cgtcactatt
     1981 gccgccagta gtaacgaggc tctgacttta tcacaacagc aacgattcga tttagtactg
     2041 attgacatta gaatgccaga aatagatggt attgaatgtg tacaattatg gcacgatgag
     2101 ccgaataatt tagatcctga ctgcatgttt gtggcgctat ccgctagcgt agcgacagaa
     2161 gatattcatc gttgtaaaaa aaatgggatt catcattaca ttaccaaacc agtgacgttg
     2221 gctaccttag ctcgctatat cagtattgcc gcagaatacc aacttttacg aaatatagag
     2281 ctacaggagc aggatccaag tcgctgctca gcgctactgg cgacagatga tatggtcatt
     2341 aatagcaaga ttttccaatc actggacctc ttgctggctg atattgaaaa tgccgtatcg
     2401 gctggaaaaa aaatcgatca gttaattcac acattaaaag gctgtttagg tcaaataggg
     2461 cagactgaat tggtatgcta tgtcatagac attgagaatc gcgtaaaaat ggggaaaatc
     2521 atcgcgctgg aagaactaac cgacttacgc cagaaaatac gtatgatctt caaaaactac
     2581 accattactt aatattatct taattttcgc gagggcagca aaatgaaaga atataagatc
     2641 ttattagtag acgatcatga aatcatcatt aacggcatta tgaatgcctt attaccctgg
     2701 cctcatttta aaattgtaga gcatgttaaa aatggtcttg aggtttataa tgcctgttgc
     2761 gcatacgagc ctgacatact tatccttgat cttagcttac ctggcatcaa tggcctggat
     2821 atcattcctc aattacatca gcgttggcca gcaatgaata ttctggttta cacagcatac
     2881 caacaagagt atatgaccat taaaacttta gccgcaggtg ctaatggcta tgttttaaaa
     2941 agcagtagtc agcaagtcct gttagcggca ttgcaaacag tcgcagtaaa caagcgttac
     3001 attgacccga cgttgaatcg ggaagctatc ctggctgaat taaacgctga cacgaccaat
     3061 catcaactgc ttactttgcg cgagcgtcag gttcttaaac ttattgacga ggggtatacc
     3121 aatcatggga tcagcgaaaa gctacatatc agtataaaaa ccgtcgaaac acatcggatg
     3181 aatatgatga gaaagctaca ggttcataaa gtgacagagt tacttaactg cgcccgaaga
     3241 atgaggttaa tagagtatta accaggggca tccgatggta ttaagcattg gtcatatttt
     3301 gatgagcctt acgccacgca gtattgctca tcatcgacaa aatccatacg gatgccctgg
     3361 tatgccgcac catttatcac taccttagtc ttcatttaat catgatatag tagaatcccc
     3421 ttatttaacg ggctttacca tgtcgtattc tatcggcgaa tttgccagac tatgcggtat
     3481 caatgccgcc acgctaaggg catggcagcg acgctatggt ttattgaaac cgcagcgtac
     3541 tgatggcggg catcgcttat acagcgatga cgatattcga caagcgctta gcatcctcga
     3601 ctgggtgaga aaaggcgtac cgataagtca ggtcaaaccc ttactgtcgc gtccggtcat
     3661 tcgcctgggc gataactgga taacgattca ggagacgatg cttcaacatc tccacgaagg
     3721 gcgaattgac gcgctgcggc agttgattta tgactgtggc cgggaatatc cccgcgcaga
     3781 actggtgacc catttattgc gtccgttgcg cagcaaagtg tccgcgcatc ttcccgccgt
     3841 gatgacgctg cgcgaaatat tggatggcat cattattgcc tacacctctt tttgccttga
     3901 aggcgacaga aaagcgcctg gcaacaatgc ttttattagc ggatggcatc tctcggatca
     3961 ctgtgaaatc tggctggaag cgttgactcg taccggacaa gagctgcggc tcaatgtgct
     4021 tccctctcca ccagccgttc tggcgcccga gctgttcgcc cagagaaaat ggttcctggt
     4081 gaccaccggc aagctcactg ccgggcagaa aaaacagctt gcccagtggc gcaacgtggt
     4141 cgcttcgctg gaggttatca cactataagc gctgaaatag atttcttccc ctcattctat
     4201 cttattgata tttaagtaca tcaaaaaaat ctccgcgaaa acttagacaa aaaaacaaag
     4261 ttgtgtaagt tttaaatcag cgtgagataa cattttgcgc cgttggcgtc agtcgtcgta
     4321 ctttcaataa gggggaatca tgaataacaa acccgtagtc ggcattagcg gatgtctgac
     4381 tggcgccgcg gtacgctttg atggcggaca taagcgtatg gattttgtca tgaactctct
     4441 ggcgccgtgg gtggcctaca aaccgatctg cccggaggtg gcgatcggcc tgcccgtgcc
     4501 ccgccctgcg ctgcgtctta tccagacgac ctgtggcgac attcggatgc gctatagcca
     4561 tgccccgcac gatgacgtca ccgagcgaat gaatgccttt gccgatcggt ttctgccaac
     4621 aataggcgaa ctggcggggt ttattgtgtg tgcgaaatcg cccagttgcg gaatggagcg
     4681 cgttcgcctg tatgatgaaa agggtaacag gggccgcaaa gctggcacgg ggctgtttac
     4741 cgccgcgatg atggacaaat atccctggct gccgatagag gaagatggtc gcctgcacga
     4801 tccggtacta cgcgagaatt tcatcgcacg tatcttcgcg ctacatgaat taaatgcgct
     4861 acgcgcgcag ggcttgagtc gtcacagttt gctcgcgttt catagccgat acaaacttca
     4921 gcttctcgcc caccaccagg ccggctaccg cgaaattggc cctttcgtcg cgcgtctgca
     4981 tgagtgggac gatctggatg ccttctttgt ccgatacaga gaaaaactga tggctatcct
     5041 gcgacacccc gcttcacgta aaaatcacac caatgtgctg atgcatatcc agggctattt
     5101 tcaccgcgcg ttgaacagca ggcaacgcgc ggaattacgc gaggtgattc tcggctaccg
     5161 ggcgggccga ctacctatcc tggcaccgtt aacgctgctg aagcactatc tggcggaaca
     5221 tccggatgac tatctacgca gccagaatta ttttgagccg taccctgata cattagggct
     5281 gcgcttagcc atcacctgat aaccctgcgc atcgctaacg gcgggtaacc agcccgccat
     5341 ggtgacaatc gcgacaattc aaaggcgatt tcgttattgc caccctgata gcggctatga
     5401 ccgcgccaga gcgttaatca cggtttccat agcctgtttt tctaacgcgc tacgttggat
     5461 gcgttgattc gccagcgcgg ttcttaacac gcccgcaata acaatatatt taggctcctg
     5521 ccccagatcg cgcatttcca gcacgacctt gcccaccacc cggcacatct cgcggtacag
     5581 ttcgtcatct tttgtcggtt ttgtcatacg ttttactcgt cgccagctca aaccaacaga
     5641 atataacagt cttctcaatt aaacaaaatt tgatgcaaat caaagaaata acgcagttta
     5701 ttattcatgg ctcatacgtt gttcgtattc tggtctctgg cgaggccatt ttttcgaaac
     5761 gcctaatcag ttccgccagg ctaccggcct gcattttttc catgactctg gcgcggtgca
     5821 cctctacggt acgcaccgcg atattcatcg cttccgcaat ttcacggttc ataaaccctt
     5881 ttgccaccag gctggccagc tcacgctctt tcggcgtcaa ctgctggtaa cacagtataa
     5941 tctcacggcg cgccaccgct gccgatgaaa ccgtcagcgc acgctccagc gccgcctgta
     6001 gcggttttac cgataccggt ttttgcagaa aatcgacggc gccgcgtttc atctgctcca
     6061 cggccatcgg tacatcgcca tgcccggtaa gaaaaacaac cgccagggta cttccgcact
     6121 ggcgcaacgc atcatgaacg ccctgcccat ccagtaccgg cattcgcata tccagtaata
     6181 cgaccccggc ctgatacaga ctggcctgcg ccaaaaaatc cgccccctgc gtccagcatt
     6241 ttacgtcata tcccagactt tccagtaaaa acgcgcacgc gttagtgacc gccgtatcat
     6301 catccagtag atgaattgtc gccatccctg cccccatgtt catgtaagaa atgtatcgtg
     6361 accaccgttc ccgacagacc gtccggcgcg gtctggttcc tgatgctgat atcgccccgc
     6421 ccataccgca ccagccgctg gcaaatcgcc agccctaagc ccatcccctc tttacgggtg
     6481 gtcataaacg gctgaaacgc ctgacgtaat agcgcctcgt cgattccccc ggcgttatcc
     6541 tgtaaaacaa tactgatgcc gttttcagtg cgttcagcaa cgacccataa atgggtggcg
     6601 cccgcctgag ccgcattaag aatgatattc gccagcacct gttccagcag cactgacggc
     6661 agcgttacgc gcagcgcagc gctaacctcg gtatgcagag tcactgtcgg aaattgttgc
     6721 gccatacgca acaattgcca gacatgatca atcgcctcgc gaatggctat ggccttccac
     6781 gcttcggtta gcaccgggtt gccctgcgcc tggctgaccc agtgacgcag gttacgcaga
     6841 gtatccgcac cgcgttgcgc ctgctggtca atctgctcca gcgccggcag caagggatgc
     6901 tgttcatctg cagcgcgcag tcgaatcagg cacccctggg cataatgtcg aatcgcggaa
     6961 agcggctgat taagctcatg ggcaaacccg gaggtcattt cacccaacac gctcatttgc
     7021 cgggcggttt ccagcgcccg ctcatgctga tgaagaacta cgctattacg ttccagttgc
     7081 tttccacgtc gacgcaccag cagcatgacc caaatataat tgagcgtgag caacaggaac
     7141 gccaaaatca cgccgccgac cattagctgg tgctggatta accaactttt gacatccagc
     7201 cacagtcgac gctgctgagg gtgctgacga acatcacgca gcaacgcttc cacctgactg
     7261 gtcgacgctg gcgcgcccca gtgaaatgac gcggcggcgg gcgcgttgaa tagcgctcgc
     7321 gttacgcgat ccgccagcgc atcgcttacc gcaggtagcg ccgcgaacga ccagtcagga
     7381 tataacggcg tactggttaa gcaaggcagg ggcgtcggtc gggaaagcag cgcgataaag
     7441 tcctttttat taatcaatcc ttcctgatcc atattttcta acaggcacac tggcacaatt
     7501 gccgcctgca ccgctttttc gcgcagcata tagattaagg catcgccagg aaatccggta
     7561 aaacgaagat gaaaatcgcg ctccgggcgt aagcccgcgt cgctgagcgc tttatagcct
     7621 aataaatagc cgccaaacgc ctgagcatca atcgcgccga ctgtcttacc gatgagatca
     7681 tgcgccgtgg tgatgccgct atcgcgccgg gtcaaaatca cgctgccaat aacattgctc
     7741 accgctttcc catcgcgcgt ggaacgcagg gaagctaacc agcgcagcgg cgcatggctg
     7801 ttcagttgga caaattgcgc cgggttggtt atcacaaact gcacggttcc ctggttaacg
     7861 gcctcctgca tttgatgcag atccagcggc tggatgtgaa aggtttcgcc tggaagctgt
     7921 tggcttaatg tctttgccaa cggttgccag tggctacgcg tagacgcctc gccgcgcatg
     7981 gccaaaatac cgatattcca cgtccctgcc cacgcgccat gacaaagtag ccctactgcc
     8041 gccaacaccg ccaggcgcct tacggtttta cctctcaccc caatatccct gtcaattatg
     8101 ttgttttaga tcaacaacaa gccgggtatg tggttaacca caatagagcg caccccgtct
     8161 cgatttttac actgtaaatc atcaacattt tttattcatt acacatgaac caacatcgtg
     8221 acaaatgttt cattgttggc aatgtggacg ggagtcaata tggacagcag taaacggcaa
     8281 tttctccagc agctcggcgt cctgaccgct ggcgcctcgc tggttccgct ggctgaagcg
     8341 aaatttcctt tttcgccgga gcggcatgaa ggctctcccc gacaccgtta cgccatgctt
     8401 atcgacctgc ggcgttgtat cggctgtcag tcctgtaccg taagttgcac tattgaaaac
     8461 caaacgccgc agggcgcgtt tcgtacgacc gtgaaccaat accaggtcca gcgtgaaggt
     8521 agtcaggaag tcacgaatgt gctgttgccg cgtctgtgca accattgcga taaccccccc
     8581 tgtgtgccgg tctgcccggt acaagccacc tttcagcggg aagacggcat tgtggtggtg
     8641 gataacaaac gctgcgtcgg ctgcgcctat tgtgtccagg cgtgtcctta cgacgcccga
     8701 tttatcaatc atgaaacgca aactgccgat aaatgcacgt tttgcgtcca tcgtctggaa
     8761 gccggactgt tacccgcttg cgtagagtcc tgcgtcggcg gcgcgcgtat tattggcgat
     8821 atcaaagatc cccatagccg catcgccacc atgcttcatc aacatcgcga cgctatcaag
     8881 gtattaaagc cggaaaacgg cacgtcgccc catgttttct acctgggtct ggacgacgcc
     8941 tttgtcaccc cattaatggg ccgtgcgcag cccgcgcttt ggcaggaggt ctgaatgacg
     9001 cattcactca tcattgaaga agtgctggct cacccgcagg acattagctg gctgccgtgg
     9061 gcggtacaat atttcttttt tattggcatt gccgcctgcg ccgcactgtt tgcctgttat
     9121 cttcactggc ggaaaaaaga cgccgcaaca gaagaaaatc gggcattact gattgccatt
     9181 acctgtgcga ttaccgcacc gctggcgctg acggcggatc tgcaccagac cgcccgcgtc
     9241 tggcatttct atgcctggcc gacgccctgg tcgtggatgc cctggggagc gttgttcctg
     9301 ccgctgttta ccggatttct cgctctgtgg ttcctggcgc agcaaataaa acgattattc
     9361 aataaaagtt acaacgtcac taaatggttg gcgttagcca gcgcgctttg cgcggtgggc
     9421 ctgttgattt ataccggccg cgaagtctcc gttgtgctgg cgcgcccaat ctggtttagc
     9481 tacgccttcc ccgtggcgat gtttcttagc gccttacagg cgttcttcgc gctgatgatt
     9541 gtcgccgccc gacgcgactc ggtaaggctg ccaaaaatac tgtggggaca actctggacg
     9601 ctggcggcgc tggggctggt tgtggccatg tgggtcagcg gcgatacgct ttccggcacg
     9661 gcaatccgtc agtggattac cgtcgccctg tcagccaaat attacgctgt cggctggcta
     9721 gcgctgtggg tattcacact gctgttctgt agcctggcgc tacgtcatcc gttatcggag
     9781 ctaagacgcg tcctgctggt tctgagcgcg ctggcgctat gttggctgat gcgctggaca
     9841 ttgttgattc aggtacaaac cgtacccaag ttcaacgcgc aatttaaccc ttacacgtta
     9901 ccaggcggaa cggatggctg gctggctatt ctcggcacct tcggcctgtg gatagcgcta
     9961 ctgattagta ttcgtgaaac gctgaacgga ctcaccagga gattacaaca tggctaattt
    10021 aacccgtcgt cagtggctaa aagtcggtct cgccgtcggt gggatggtca cttttggtct
    10081 gagctaccgt gatgtggcga aacgcgcaat tgatggcctg ttaaacggga catccggcaa
    10141 ggtaacgcgc gaccgcatct ttggcaacgc gttaattccg gaggcgcagg cacaaacgca
    10201 ctggcagcaa aatccacaac aaaccatcgc catgacgcaa tgcttcggct gttggacaca
    10261 gtgcggtatc cgcgcccggg taaatgccga tggcaaagta atacgcatcg ccggcaatcc
    10321 ctatcacccc ttgtcgcagg aacacccgat tgactcgtcc gtccctttta gcgaagccat
    10381 ggagcaactg gcgggagaaa gcggtcttga cgcccgctca accgcctgcg cgcgcggcgc
    10441 cacgctgctg gaaagcctgt acagtccgct gcgactgctt gaaccgatga aacgcgtggg
    10501 taaacgcggc gaagggaaat ggcagcgcat cagctttgag cagcttattg aagaagtcgt
    10561 ggaaggcggc gatctgtttg gcgaaggtca tgtggacgga ctgcgcgcta ttcatgcgcc
    10621 ggatacgcca attgacgcaa agcaccccag tttcgggccc aaaaccaatc agttactggt
    10681 cacgaatacc agcgacgaag gccgcgatgc gtttctgcgt cgttttgcgc taaatagctt
    10741 cggcagcaag aatttcggcg cgcatggcgc ctactgtgga ctggcttacc gggccggctc
    10801 cggggcattg atgggcgatc tggataaaaa cccgcatgtc aaacccgact gggaaaacgt
    10861 ggagtttgcg ctctttatgg gcacctcccc ggcacagtcc ggtaatccct ttaaacgcca
    10921 ggcgcgtcag ttggcgagcg cccggctgcg tgagaatttt caatacgtcg tggtcgcccc
    10981 cgccctcccc ttatcaacgg tgctcgccga tcctcgcggt cgctggcaac cggtcatgcc
    11041 cggcagcgat tcggcgctgg caatggggat gatccgctgg atcatggata atcaacgtta
    11101 taatgctgat tatctggcga ttcccggcgt acaggcgatg cagcaggccg gcgagcaaag
    11161 ttggaccaac gccacgcacc tggtcattgc ggatgaactg ccgacgcttg ccggacaaca
    11221 cctgacgctg cgccatctta cgcccgatgg cgaagagacc cccgtcgtgc tgaataccga
    11281 cggcgagttg gtcgatgcgt ccacttgccg acaggcacgg cttttcgtga cgcagtacgt
    11341 tacgctcgcc gacggccaac gggtcacggt gaagagcggg ttgcaacgcc tgaaagaggc
    11401 ggcagaaaag ctctcgttgg cgcaatacag cgaacagtgc ggcgtgccgg aagcgcaaat
    11461 tatcgcgctg gcggaaacct ttatcagtca cggacgtaaa gctgcggtca tcagtcacgg
    11521 cggcatgatg gccggcaatg ggttttataa cacctggtca gtcatgatgc ttaacgcgct
    11581 gatcggcaac ctcagcttgt ccggcggcgt ctttgtcggc ggcggcaaat tcaacggcgt
    11641 tagcgacggc ccccgctaca acatgaacag ttttgccgga aaagtgaaac cgtccgggtt
    11701 gagtattgcc cgtagcaaaa ccgcttataa agcatcggaa gaataccgcg acaaaattgc
    11761 cggcgggcaa tccccttatc cagccaaagc gccatggtat ccctttgtgg caggccagct
    11821 taccgaactg ttgacctccg cgctcgaagg ctatccttat ccgcttaaag cctggatttc
    11881 caatatgagc aacccgtttt acggtgttcc cggtctacgc gccgtggcgg aagaaaagct
    11941 aaaagaccct cgccgactgc cgctctttat cgcgattgac gcctttatga atgaaacgac
    12001 ggcgctggcg gattacattg tgccggatac gcacaatttt gagagctggg gctttacggc
    12061 gccctggggc ggcgtagcca gtaaagccac taccgcccgc tggccggttg tcgcccccgc
    12121 cactcaccga acggcggacg ggcaacctgt ctcaatggaa gcattttgta ttgcggtagc
    12181 aaaacggctc catctgcccg gcttcggcga ccgggcgata accgatccgc agggcaatac
    12241 ttttccactg aaccgggcgg aagacttcta tctgcgcgta gccgctaata tcgcctttat
    12301 gggcaagacg ccggtcgcgc tggcaaatca ggaagatatt tcgcttaccg gcgtcagccg
    12361 cattctgcca gcaattcagc acacgcttaa agctgatgag gtcggtcgcg tggcgtttat
    12421 ctactcgcgt ggcggccggt ttgcgcccga agatagcggc tatacggagc aacggttagg
    12481 taacgcgtgg aaaaaaccct tacagatctg gaatgcagat gtcgccgccc accgtcacgc
    12541 catcaccggg gagcgcttca gcggttgccc ggtctggtat ccggcgcgtc tgtcagatgg
    12601 tcgtgcgatt gacgaccagt ttcccattgg acagtggccg ctgaaactga tttcatttaa
    12661 atcaaatacc atgtccagct caacagccgt catcccgcgc ttacaccatg tgaagccagc
    12721 aaacctggtg gcgctgaatc cgcaagacgg cgagcgttat ggactgcaac atggcgatcg
    12781 ggtacggatc attacgccgg gcggtcaggt cgtggcgcaa atcagtttgt taaatggcgt
    12841 gatgccaggc gtcatcgcca tcgaacacgg atatggccac cgcgagatgg gcgcaacgca
    12901 gcactctctg gacggcgtgc ctatgccgta tgatccacaa atcagggcag gcataaatct
    12961 taacgatctg ggctttgctg atccgacaag aaccattacc aacacctggc tcgactgggt
    13021 ttctggcgcg gcggtacgtc aggggctgcc ggcaaaaatc gagcgtatat aaccccaggg
    13081 ccggagagcg atatcgtctt atttcgtcga gggtagcgac tgataagcga atgctgtccg
    13141 gctgcatata ctcactgaat cgtgcaagcc caactatttt acgttcaccc cgtcatatta
    13201 catagaaaat atatgacaac actcacaaaa ctattttccc cttctgtaag caattaatat
    13261 ttaacacatt ggctgcgctt ctgattattg acattcattt gggattactt ccggttgacc
    13321 gcataatctg tgattgaatt caccgcatga caatattgcc ataaatacaa ttcaactcac
    13381 tacccggagg caatatgttt aaagaagaaa gacgtcatgc catcattaat ttactgataa
    13441 aggataatag tgttagcgtc agtaaacttt cagaccttta taaggttagc caggagacta
    13501 ttcgttccga tctacgctat ttccagaaat caggtatgct tcagcgttgc tatggcggag
    13561 ggattttaaa ccgtgacgcg ctgagtaagc ttatcactga aaataagatt gatatctcca
    13621 gcactatcgc cacgccaatc catcaggatg caaaactgca ccgggaaaac acaaaaaaag
    13681 caggcaaggt gtgtgtttta ggctcattca atattgatgt ttcagcaacc gtgccgtggt
    13741 ttccacaaag cggagaatcc attctggcca gtcaatttgg attctatcct ggcggtaaag
    13801 gagccaacca ggctttagcg gcaaacaatg ctggtgctgc ggcgcatttt atttttaaag
    13861 tgggcaaaga tcagttcagc gcatttgcta tgaatcatat tattcaatca ggcaccacct
    13921 catacagcgc gtatcaaaca gataaagcgc ccaccggtag cgcattgatc tatgtctccg
    13981 ccgtggatgg cgataatatt atcgccatct accctggcgc caatatgatg ctcaccacgc
    14041 aagagattaa cgagcaacac cgttatatcg ccgagtctga cgttatgtta atgcagctcg
    14101 aaacgaacat tgaagcgttg actgaattta ttcgcctggg caaacaagaa aataaaatga
    14161 tcatgctgaa tcctgccccc tatacgaaac aggtgacgca tttattatct gatattgaca
    14221 tcatcacgcc gaatgaaact gaagcctctt ttttatccgg cgtaaccatt actgatatta
    14281 atgatgcgaa aaaagccgga aatattattc tgcaatccgg ggtgaaaaaa gtcatcatta
    14341 cccttggcgc ccgtggttct ctgctctgtg agcacgcccg cacgttgtat attcctgcgt
    14401 ggagcgccgt ggtaaaagat gccgccgggg ccggtgacgc ttttaatggc gccttagccg
    14461 ccgcgctggc gcgacaagca gatatggtcg cagccattca atatgcctcc gctttcgctt
    14521 ctctggcggt ggaacaagtc ggtgcgtcga gtatgcctca gcacttgcag gttttacatc
    14581 gaatgcgtac ccaatctaat aaagtcattc acattaatta acaggtgaca taatgaaaat
    14641 cttatttatt ggcgaatcct ggcacattca tatgattcac tctaaaggtt ttgatagctt
    14701 tacatcgagc aaatacgaag aaggcgcaga ctatttatta tcctgcttac gccagggtaa
    14761 tatcgatgtg gactacatgc ctgcccatat tgtgcaaact cgttttccac aaaccgccga
    14821 agcattagcc tgctatgatg cgatcgtcat cagtgatatc ggtagcaata cgttcctgtt
    14881 acaaaacaga accttttata atatggacat tattcctgat gcattacaac ttatcgccga
    14941 ttatgttgct gagggcggcg gtctgttaat gatcggcggg tatttatcct ttacgggaat
    15001 agaagcaaaa gccaattata aaaatacggt tctggcggag gtattgccgg ttgatatgct
    15061 ggatgtagat gaccgcgtag aactaccgca aggatgtaaa gcagtaaata ctgcggtaaa
    15121 acatgttatt acccagccat ttagcgaatg gccgccgctg ttgggctata acaagcttat
    15181 cgccaaagaa aatagtcagg tccttgctga aattaatggc gatccactgt tagttatggg
    15241 tacttaccat aaagggaaag tatgttgctt tgccagtgat tgttcgccgc actggggaag
    15301 tccgcagttt ctgcaatggg aacattacgc caccttctgg tgtaatgttt tacacacaat
    15361 aaaaaaataa tattacccag gcgaatataa atttcgcctg ccctgccaca cactgagtca
    15421 ttaagaatat gaatgatact tatctctatg gcgaaatgtt ttctgaaaac atattgacaa
    15481 gctatcggat ttatggcgac agaaaatcat tactcacgcc gctcattatc cttcatggcg
    15541 gcccttctgg cggctttgat tatttattaa attatcgccg tctggctgat gacgggcgca
    15601 tggtaatatt ttacgatcaa tatggttgcg gtcgttcaac gcattttcct catgccgacg
    15661 cgtctttctg gactattgcg cgttatctcc gtcaattaac ccaattaatt catcacctgg
    15721 gtattgggca cgggtattcg atactgggac attcctgggg cggaatgctt gccgcagagc
    15781 acgcctgctt acagcctgcc gggcttcgcg ggacgatact ggccagttcg ccgccgaccc
    15841 tacgggttat cacattttat ggggaaccaa tgaactggcg gcaaatggca aacttgccga
    15901 ctgggatatt acgccccatt tgtgccagat acgctgtcct gttctggtac tacgcggcga
    15961 aaacgatcag gcaaccgagc gcgtcgtctc tccgctgctc tctcacattt cagactgccg
    16021 cgcggtcact attcctggca gcagccataa cccgcatgaa gaaaatatcg cgccctgcct
    16081 cgcagaggta agcgcgtttt tacgcgatct ggcataaaaa gccattaaga tatttatcat
    16141 gaaaaaagtc aaaaaattgt ctcttaccga tttagtgctt tatggtctgg tgtttatggt
    16201 gcctatcgca ccagtctctc tttatggcgt cgtttataat ctttcgcacg gtatggttgc
    16261 gctggtttat attattggcg ctatcgcgat gttttttacc gcgtacagct actctacctt
    16321 atcgcagcat atctcctcgt cgggttcggc ctatgcgtat gctggcgtat gcattaatcc
    16381 cgccgtaggg tttctgaccg gatggatatt actgctggat tatcttttgt tccctacgct
    16441 cgtagcggtg ctgggcggtg tcgcggtcca cgctatttta ccgcaaatcc cggtctgggt
    16501 ctggccgttg atttatgtgg ctattggcac cggagtcaac tatctcggga tacagcaaac
    16561 ggcgaaattc gataagttac tggtctttat tcaactcggt attctggcga ttttcgtgct
    16621 actcattatc cgtctgatga tgcaggacag tagtcagata acgctttcct tccggccttt
    16681 tttcgattca cagtggttca cccctgggct catcgcaacg gcgatttcgg tggctgcgct
    16741 gaattttctc ggctttgacg ctatcagtac attaagtgaa gaaagcgaag gcgggggacg
    16801 cgccgtcagt aaagcaacac tgttggcgtt agttttggcg acggtactgt ttattatcgt
    16861 tgtggcgttt gcggcgttcg ccaccggtaa cgtcgaccgc ttcgcggaag gtaatgcgac
    16921 gaatgaagca tttttcacca ttgccggcaa cgttggcggt atctggctca aagtggcgtt
    16981 ttccatcatt gtggcgtttg tgtgcgccgt cggcaacatt attaccgcgc aaacggcggt
    17041 gtccagagtg ttattttcaa tggggcgcga ccgaatgttg cccgccttcc tcgctcacgt
    17101 ccataccacg cgtaaaacgc cggattatgc cattctgttt accggcggcg tcaccctgct
    17161 gctcagctac ctgttttccg gcaagattga atctatctcc acgctggtga actttggcgc
    17221 gcttttcgct ttttttgtcg tgaacctgtg tgtgtttatc ctgttcaatt tccggatgaa
    17281 agcccagcgg cgcattttcg cccatgtcat ttcgccgatc atggggatga tcgtcatcgg
    17341 ctacgtctgt ttaaacatga acattcacgc tctgatactc ggaattagct gggcggcgat
    17401 cgggatagcg atactgtgct accgaaaagc atacaaccaa aacatcgcca tcgacctgga
    17461 aggcaaaaag ttgctcgatt gacattatgc gcaacaacac cagctgttgc gcaacgccgc
    17521 ccctgttcgg gcggcgtcat cgccagcgac atcgtaaaca gcgtaataac aaaccgttgt
    17581 ggatctgcac agatgtcttt tgaaacaggg ttttcatttt ccttttttgt aaatttcagc
    17641 gtataatgcg cgccaattgt ctcttgaatg gtttcagcgc attggactgt aaaactcaac
    17701 gactaaaatt atccccttcc cgttgggctg aaacgcgagc acacattcct ctgcacgctc
    17761 tttcgatgtc acctatcctt agagcgaggc atcatcactt tagcaacaca ggcttagctt
    17821 acgggccgtg cgcgcccgaa gccagatttc catatcctcc tcaacttaaa gactaagact
    17881 gtcatgaaaa agacgaaaat tgtttgtact atcggtccga aaaccgaatc cgaagagatg
    17941 ttaagcaaaa tgctggacgc gggcatgaac gtgatgcgtc tgaacttctc tcatggcgat
    18001 tatgcagaac acggtcagcg tatccagaac ttgcgcaacg tgatgagcaa aactggtaaa
    18061 aaagctgcta ttctgcttga tactaaagga ccagaaatcc gcaccattaa actggaaggc
    18121 ggtaacgacg tttcgctgaa agcgggccaa acctttactt ttaccaccga caaatccgtg
    18181 gtcggtaata atgaaatcgt tgccgtcacc tatgaaggct tcaccagcga cctgagcgtt
    18241 ggcaacaccg tcctggttga cgatggtctg atcggtatgg aagtgaccgc catcgaaggc
    18301 aataaagtca tttgtaaggt gctgaacaac ggcgatctgg gcgagaacaa aggcgttaac
    18361 ctgccgggcg tttctattgc tctgccggcg ctggctgaaa aagacaaaca ggacctgatc
    18421 ttcggttgcg aacagggcgt tgactttgtt gctgcgtcct ttatccgtaa acgttctgac
    18481 gttgtcgaaa ttcgcgagca tctgaaagcc cacggcggcg aaaacatcca gattatctct
    18541 aagatcgaaa accaggaagg cctgaacaac ttcgatgaaa ttctcgaagc ttccgacggc
    18601 atcatggttg cgcgtggcga cctgggcgta gaaatcccgg ttgaagaagt gatctttgcg
    18661 cagaaaatga tgatcgaaaa atgtatccgc gcacgtaaag tcgtgatcac cgcgactcag
    18721 atgctggatt ctatgatcaa aaatccgcgt ccgacccgcg cagaagcagg cgatgttgca
    18781 aacgccatcc tcgacggtac ggatgcggtt atgctgtccg gcgaatccgc aaaagggaaa
    18841 tacccgctgg aagccgtttc tatcatggcg accatctgcg aacgtaccga ccgcgtcatg
    18901 aacagccgtc tggactacaa caacgacagc cgtaaactgc gcattacgga agcggtatgc
    18961 cgcggcgcgg tagaaaccgc cgaaaaattg gaagcgccgc tgatcgtggt agcgacccag
    19021 ggcggtaaat ccgctcgcgc cgtgcgtaaa tacttcccgg acgccaccat cctggcattg
    19081 accaccaatg aagtgaccgc ccgtcagtta gtactgagca aaggcgtggt atcgcagctg
    19141 gtgaaagaaa tcaattctac tgatgatttc taccgtctgg gcaaagatgt cgccctacaa
    19201 agcggcctcg cccagaaagg cgacgtcgta gtgatggtct ccggcgcgct ggttccaagc
    19261 ggcaccacta acaccgcctc
//
LOCUS       DAJVKX010000082        18833 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000082 DAJVKX010000000
VERSION     DAJVKX010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18833
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.082"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            99..380
                     /locus_tag="OPY25_002959"
     CDS             99..380
                     /locus_tag="OPY25_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HCS0928522.1"
                     /translation="MKKYLLMGIIVSAYGISVPVFASDTATLTISGKVTAPTCSTEVV
                     NAQLQQRCGNTIHVSTLQTPAATPMRGVTTQLYTVPGDSTRQIVVNHYD"
     gene            659..1189
                     /gene="yehD"
                     /locus_tag="OPY25_002960"
     CDS             659..1189
                     /gene="yehD"
                     /locus_tag="OPY25_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein YehD"
                     /protein_id="HCS0928523.1"
                     /translation="MKRSLIAASVLSAVFMSAGAFAVDEYDSGVLNINGKVVGTTCQF
                     LGTNTAEIRLNEIGADKIINLTPGQIYDAVTNQTQMPLKIKCQQGVAPRITFSSTQFD
                     SHDITFNNGSAKGVGFAVYYGSTDNQIDPETGVTLDPNSSGEYDLTFLARYARLDGDV
                     ASGDVSSTLTLTVVTD"
     gene            1245..1928
                     /locus_tag="OPY25_002961"
     CDS             1245..1928
                     /locus_tag="OPY25_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HCS0928524.1"
                     /translation="MKILSAVLLSAIILPAHAGIVIYGTRVIYPAEKKEVVVQLVNQG
                     EQASLVQSWIDDGNTSLPPEKIQVPFMLTPPVARVAAESGQQIKIKKMPNSLPDNKES
                     LFYLNVLDIPPNSQENAGKNVLKFAMQNRIKLIWRPSRIAAVTKDSFQRIGLFRSNKT
                     VIMKNDTANWITVTDVKAGNTKINDQTIMLPPLSTQNINMKYASTSQYEVTIIDDNGN
                     YISSKINVK"
     gene            1942..4431
                     /locus_tag="OPY25_002962"
     CDS             1942..4431
                     /locus_tag="OPY25_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HCS0928525.1"
                     /translation="MLRMTPIASLVLLTLFTWQTQAIATETFDTHFMVGGMRDQKITN
                     FHLDENKPIPGQYELDIYVNNQWRGKYDIIVADDPGSTCISTELLKNIGVISDGLQPQ
                     GATDCIALKDVVRSGGYTFNIGVFRLDLSVPQAYVNEVEAGYVLPENWDRGINAFYTS
                     YYASQYYSDYKNSGSSESTYVRFNSGFNLLGWQAHADTTFNKTDGSSGEWKSNTLYLE
                     RGIAELLGTLRAGDQYTSSEIFDSVRFTGVRLFRDMQMLPNSKQNFTPLVQGIAQTNA
                     LVTIEQNGFVVYQKEVPPGPFSIADLQLAGGGADLDVTVREADGSINTWLVPYASVPN
                     MLQPGVSKYDFSAGRSHIEGADNQADFTQISYQYGLNNLLTLYGGTMLSNHYNAFTLG
                     TGWNTRIGAISLDATRAHSKQDNGDVFDGQSYQIAYNKYLTQTLTRFGLAAYRYSSQD
                     YRTFNDHVWANNKNNYRRDKNDVYDIADYYQNDFGRKNTFSANVSQSLPEGWGAVSLS
                     ALWRDYWGRSGTSKDYQISYSNTFQKINYTLSASQTYDEDHNEDKRFNLFISIPFDWG
                     DGITTPRRHLNVSNSTTFDDDGFTSNNIGLTGTAGSRDQFNYGVNVSHQRHDSETTAG
                     TNLTWNTPVATLNGSYSQSSNYTQTGGSISGGVVAWSGGLNLSSRLSDTFAIMQAPGL
                     EGAYVNGQKYRTTNKKGTVVYDNLTPYRENHLMLDVSQSSSETELRGNRKVAAPYRGA
                     VVLVNFDTDQRKPWFIKAQRPDGSPLIFGYDVVDHHGHNVGIVGQGSQLFIRTNDIPP
                     EVSVPVDKEQGLSCSITFGKTVDESKVYICR"
     gene            4447..5454
                     /locus_tag="OPY25_002963"
     CDS             4447..5454
                     /locus_tag="OPY25_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HCS0928526.1"
                     /translation="MKLFLFIVMLLILPETYAACTGEITYQDNLIIREDFTINPNQSA
                     TYSHNFNDTTCSGTYKITRMDPSDIIVGLYNDTVKLKLKIAWADNNTLTMPFTTGYTV
                     TVEPASSGANVNISAGSGNSVLINGVVSITSASSATQFTASLRFLGCLLAGRGWNACA
                     ADYNSYLRGAGLYSFDLFVSYDRKQTTCKPEDLTITLPNIALSELYNTGKVSNKNAAD
                     NIRLQCDNLFGNAKQTSRKMTVYLSSSDLIPDSYSVLRGAVNNGVGFILESGGKTVNI
                     SNTAEQGNASTLWKVDQVGTPLNSDMITIPIIASYYVYDRDNIKPGDLKATALIYVKY
                     D"
     gene            complement(5716..6030)
                     /gene="rcnB"
                     /locus_tag="OPY25_002964"
     CDS             complement(5716..6030)
                     /gene="rcnB"
                     /locus_tag="OPY25_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HCS0928527.1"
                     /translation="MKSKLLPCALLLATSFAWAAPATTGIDQYELKSFIADFTHFKPG
                     DTVPQMYRTDEYNIKQWKLRNLPAPDAGTHWTYMGGAYVLINDTDGKIIKAYDGEIFY
                     HR"
     regulatory      6312..6408
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6440..7237
                     /gene="thiM"
                     /locus_tag="OPY25_002965"
     CDS             6440..7237
                     /gene="thiM"
                     /locus_tag="OPY25_002965"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HCS0928528.1"
                     /translation="MQPDLHCRTLAAHTLKHFRALSPLTHCMTNDVVQTFTANTLLAL
                     GASPAMVIDPVEARPFAAIANALLINVGTLTASRADAMRAAVESAYDAKTPWTLDPVA
                     VGALEFRRRFCLDLLSLRPAAIRGNASEILALSGMALGGRGVDTTEAALAALPAAQAL
                     ARQIDCIVVVTGEIDYVTNGQRTLSIPGGDPLMTRIVGTGCALSAVVAASCALPGAAL
                     DNVASACCWMKLAGQVAAERSEGPGSFIPAFLDALYHLDMEAANATN"
     gene            7224..8024
                     /gene="thiD"
                     /locus_tag="OPY25_002966"
     CDS             7224..8024
                     /gene="thiD"
                     /locus_tag="OPY25_002966"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCS0928529.1"
                     /translation="MQRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTCGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRHHVRNV
                     VLDTVMLAKSGDPLLSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLA
                     QGRALLAMGCEAVLMKGGHLEDAQSPDWLFTREGEQRFSAPRVNTKNTHGTGCTLSAA
                     LAALRPRHRCWGETVNEAKAWLSAALAQADTLEVGKGIGPVHHFHAWW"
     gene            8060..8806
                     /locus_tag="OPY25_002967"
     CDS             8060..8806
                     /locus_tag="OPY25_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0928530.1"
                     /translation="MEQAHTRLIAQLNERISAADNTPLYMKFAQTVKDAVRSGILEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRARGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVSCPDEVAQHLAIPAGSDVFLLKRIRYVDEDAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRRQHIYPQRTRSRVSARMPDDEFQSHIQMDGKVPVLVI
                     KQVALDQQQRPIEYSISYCRSDLYVFVCEE"
     gene            complement(8780..9745)
                     /locus_tag="OPY25_002968"
     CDS             complement(8780..9745)
                     /locus_tag="OPY25_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCS0928531.1"
                     /translation="MNGARLLTLLPTLHTRRPLTVIGAAVIDIIADAWTLPRRGGDIE
                     LQQQSVNVGGCALNIAVALKRLGIDASNALPLGQGVWAERIRRRLAKEGLSSVIDAVE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNADWLSQLRTPRGSLVYLSGYQLASSCGEP
                     LIQWLETVDDVTPFIDFGPRIGDITDDAMARIMACRPIVSLNRQEAIIAAERAGLATD
                     TRTFGEAWVKRFSAPLVVRHDKDGAWYFSAQSSGVVPAFPATVVDTIGAGDSHAGGVL
                     AGLASGWSLADAVLLGNAVASWVVGHRGGDCAPTREALLLAHKNV"
     gene            complement(9742..10746)
                     /locus_tag="OPY25_002969"
     CDS             complement(9742..10746)
                     /locus_tag="OPY25_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCS0928532.1"
                     /translation="MKAERILGALYGQALGDAMGMPSELWPRTRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTAMALCLADALLECEGNIDPEIIGRNILAWAERFDAFNKN
                     VLGPTSKIALNAIRDGKPIAALENNGVTNGAAMRVSPLGCLLPPTNLTAFIAEVALAS
                     SPTHKSDLAVAGAVVVAWAVSRAVNGDTWQSIADSLPAIAHQAQTARITTFSASLSAR
                     LELALNIVRHADGVESASEQLYQIIGAGTSTIESVPCAIAMVELANTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVSAINPQLKQTLDKVNQLDFARYAVALASYRQRREAL
                     "
     gene            complement(10743..12014)
                     /locus_tag="OPY25_002970"
     CDS             complement(10743..12014)
                     /locus_tag="OPY25_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928533.1"
                     /translation="MKTTFKLSFMMFVEWFIWGAWFVPLWLWLNKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSVTDRFFSAQKVLAVLMFAGAVLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYNDISPT
                     NIPLLITAASSALLGVFAFCLPDTPPKSTGKMDIKVMLGLDALVLLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLITAAIRYGFFVYGGAETYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYPQPVNGLTFNWAGMWTFGAVMIAVI
                     ALLFMIFFRESDKEITAIDDRDIALTQGEVK"
     gene            12268..13320
                     /gene="fbaB"
                     /locus_tag="OPY25_002971"
     CDS             12268..13320
                     /gene="fbaB"
                     /locus_tag="OPY25_002971"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HCS0928534.1"
                     /translation="MTDIAQLLGKDADSLLQHRCMTIPSDQLYLPGKDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPRYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPTEYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEQSRRQIEEISAAFERAHELGMVTVLWAYLRNSSFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAVNFGYTDDRVYSKLTSDNPIDLVRYQL
                     ANCYMGRAGLINSGGADGGDTDLGDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKVTIA"
     gene            complement(13373..14272)
                     /gene="yegS"
                     /locus_tag="OPY25_002972"
     CDS             complement(13373..14272)
                     /gene="yegS"
                     /locus_tag="OPY25_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HCS0928535.1"
                     /translation="MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKG
                     DAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATS
                     AGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALG
                     GVSYLIHGLMRMDTLTPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALIND
                     GLLQLRIFTGEELLPALFSTLTQSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQ
                     EFHIEVLPGALRCRLPPDCPLLR"
     gene            14837..15172
                     /locus_tag="OPY25_002973"
     CDS             14837..15172
                     /locus_tag="OPY25_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928536.1"
                     /translation="MNVTSGVNAQTPLLPPSEWGDDEKPVAEIVEFNAYGNKPRCLMC
                     LGTTALFTGAFSGVCSGAVASVSSGAAYTTALTILGASFGMGGIGMMGICAGLYLSAN
                     GVRTRPAWP"
     gene            15294..15710
                     /locus_tag="OPY25_002974"
     CDS             15294..15710
                     /locus_tag="OPY25_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CesT family type III secretion system chaperone"
                     /protein_id="HCS0928537.1"
                     /translation="MYSRADRLLRQFSLKLNADSIAFDENRLCSFIIDNRYRILLTST
                     NSEYIMIYGFCGRPPDNNNLAFEFLNSNLWFAENNGPHLCYDNNSQSLLLALNFSLNE
                     SSVEKLECEIEVVIRSMENLYHILQDKGINLDTDYT"
     gene            complement(15720..15899)
                     /locus_tag="OPY25_002975"
                     /pseudo
     CDS             complement(15720..15899)
                     /locus_tag="OPY25_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461081.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="non-LEE encoded effector protein NleB"
     gene            complement(16351..17712)
                     /gene="yegQ"
                     /locus_tag="OPY25_002976"
     CDS             complement(16351..17712)
                     /gene="yegQ"
                     /locus_tag="OPY25_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HCS0928538.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPAMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRQQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDVVGNIVHKH
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDPTLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSERQQFVGEFTGERKGQLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEQMENAKGDAMPVAPGDGYTVWMPVPQDVTLDYALLMRNFSGESTRNP
                     HAK"
     gene            17876..18493
                     /locus_tag="OPY25_002977"
     CDS             17876..18493
                     /locus_tag="OPY25_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928539.1"
                     /translation="MMKMSRTAIALSLLGMAAHPVCAAPSFEETARQVIIAFQQRDNA
                     KINALIDKKVGMYVLYRIGAGFDYKWMKKFDINKPIPDFNYLLGQVGWFSEHIPVDKE
                     FDHHTEVEYVCEKGWDHAGFFVSYTGSDNALLTFSMVNGADSGDQASDTRIANARRLE
                     LQSERVVAVPKEWGDGLIFHLSELHGLGKGWSLTLLDLVTEDCSA"
BASE COUNT         4814 a         4375 c         4916 g         4728 t
ORIGIN      
        1 tattttttca attggtttta aggtatcgat acgttcatac tgctcatcag gacggcctgc
       61 atactgtttg acgttcacca gaggaacaat tactcactat gaaaaaatat ttgctgatgg
      121 gaattatagt ttcggcttat gggataagcg tacctgtttt tgcctccgac accgcaacat
      181 taaccatcag tggaaaagtg accgcgccaa cgtgcagtac agaagtggta aacgcacagt
      241 tgcagcagcg ttgcggcaac actatccacg tttcaactct gcaaacaccc gccgctacgc
      301 cgatgagagg tgtgacaacg cagctataca cggtgcctgg tgatagcacc cgacagattg
      361 ttgttaatca ttacgactaa ttcttattaa ttccgcaggc ccatatcatt gatatcaatg
      421 atatgggctt ttttatttgt tgtgtttatg tttaagggca gtaaatttcg gaaattaata
      481 agtttacaaa ataatgataa gcaatgatta tttgttgcaa ttatattgca atctgtaaat
      541 tgttttaaat caacaaaaca tcgtgtttac attgcgataa cttcctgtct atgagaattt
      601 tcgttgcaag ggttaataac tcttaacaaa tagaaattac ttcattaagg aagagattat
      661 gaaacgttca cttattgctg cttctgtatt gtctgctgta tttatgagcg ctggggcttt
      721 tgctgttgat gagtatgatt caggcgttct gaatattaac ggaaaggtgg ttggtactac
      781 ctgtcaattt ttgggtacga acaccgctga aattagactg aatgaaattg gtgcggataa
      841 aataattaat ttaaccccgg gtcagattta tgacgcagta actaatcaaa ctcagatgcc
      901 gttgaaaata aaatgtcaac agggtgtagc gccgcgtatt accttctctt caacgcaatt
      961 tgacagccac gatatcacat ttaataacgg gtctgccaaa ggtgtcggtt ttgcggttta
     1021 ctacggaagt acggataatc agattgatcc agagacgggg gtgacactag atccaaatag
     1081 cagcggtgaa tacgacctga cttttttagc acgctatgcg cgtttagacg gtgatgttgc
     1141 ttctggtgat gttagctcaa cactgacttt aacggttgtt actgactaat ttattcaacc
     1201 ggcggcgttc gtcgccggtt ttttataagc aaggccgtgt aaatatgaaa atattatctg
     1261 cagtattatt atctgccata attttgcctg cgcatgctgg tattgttatt tatggtacgc
     1321 gtgtgattta cccggcagag aagaaagaag tcgttgtaca attggtgaat cagggcgagc
     1381 aagcttcgct ggtacagtcc tggattgatg acggtaacac ttcattaccg ccagaaaaaa
     1441 ttcaggtgcc atttatgctg acgccgccag tggcgcgcgt tgccgctgag tctggtcagc
     1501 agatcaaaat caagaaaatg cctaatagct taccggacaa caaagaaagt ctgttttatc
     1561 tgaatgtgct tgatattcca ccaaacagcc aggaaaacgc cggtaaaaat gtgcttaaat
     1621 tcgcaatgca gaatcgaata aaattaatat ggcgccccag tcgaattgcc gccgtaacca
     1681 aagacagttt tcagaggatt ggtttatttc gcagtaataa aactgtcatc atgaaaaatg
     1741 atactgcaaa ctggattacc gtgacggatg taaaagcagg aaatactaag attaatgatc
     1801 aaactatcat gctgccaccg ctatcgacgc aaaatattaa catgaaatat gcgtcaacaa
     1861 gccagtatga agtaacgatt attgatgata atggtaacta tattagtagc aaaattaatg
     1921 taaaataaac aggagttcat catgctaagg atgacgccca tcgcttcgct tgttttattg
     1981 actctgttta cctggcaaac gcaggctatc gcgacggaaa cgtttgatac tcattttatg
     2041 gtggggggaa tgagagatca aaaaataaca aatttccatc tggatgagaa taagccaatt
     2101 ccgggacagt acgaattgga tatttatgtc aacaatcaat ggcgaggtaa atacgatatc
     2161 attgttgccg atgatcccgg tagcacgtgt atttcaactg agttgttgaa aaatattggt
     2221 gtgataagcg atggtctgca accgcaggga gcaacggatt gtattgcgtt aaaagatgtc
     2281 gtgagaagcg gtggctatac ttttaatatt ggcgtttttc ggctggattt gagcgttccc
     2341 caggcctatg taaatgaggt cgaggcgggt tatgtattgc ctgaaaactg ggatcgcggc
     2401 atcaatgcat tttatacttc ttactatgcc agccagtatt acagtgacta taagaattct
     2461 ggcagtagtg aaagtactta cgttcggttc aatagcggtt tcaatctgtt gggctggcaa
     2521 gcgcatgcgg ataccacatt taataaaacc gatggcagca gcggtgagtg gaaaagcaac
     2581 acattgtatc tggagcgcgg tatcgctgag ctcctcggca cattacgcgc cggggatcag
     2641 tatacctcgt cagagatttt tgattctgtg agatttaccg gcgttcgcct gttccgcgat
     2701 atgcaaatgt tgccaaactc gaaacagaat tttacgccgt tggtgcaggg gattgcacag
     2761 actaacgctt tggtaaccat cgaacagaac ggattcgttg tttatcagaa agaggttcct
     2821 cctggcccct tttccattgc ggatctgcaa ctcgcgggcg gtggcgcgga tcttgatgtc
     2881 accgtgcgtg aggcggatgg ttcgataaat acctggctgg tgccttacgc ttccgtaccg
     2941 aacatgttgc agcctggcgt ctctaagtat gatttttccg ccggccgtag tcatattgaa
     3001 ggcgccgata atcaggccga ttttacacaa atcagttatc agtatggcct taataacctg
     3061 ttgacgcttt atggcggtac gatgctatcg aaccattata atgcgtttac cctcggcacg
     3121 gggtggaata cccggattgg cgccatttcg cttgacgcta cgcgagcgca cagtaaacag
     3181 gataatggcg atgtatttga tggtcagagt tatcagattg cttataataa atacctgacc
     3241 caaacattaa ctcggtttgg tctggctgcg tatcggtatt catcacagga ttaccgcaca
     3301 tttaacgatc atgtctgggc caataataaa aataactatc gtcgcgataa gaatgatgta
     3361 tacgatattg ctgattatta tcaaaacgat tttgggcgta aaaatacgtt ttcagctaat
     3421 gtgagccaat ccttgccaga aggatggggc gcagtatcac tgagtgcatt atggcgtgat
     3481 tactggggac gtagcggcac cagtaaagat tatcaaataa gctattccaa tacgttccag
     3541 aaaattaatt atacgttatc cgccagtcag acttacgacg aggatcataa tgaagataaa
     3601 cgttttaacc tgtttatttc aattcccttt gactgggggg acggtattac taccccgcgg
     3661 cgtcatctga atgtgtcgaa ctcgacgacc tttgatgatg atggatttac ctcaaacaat
     3721 attggtttaa ccggtacggc aggcagtcgc gatcaattta attacggcgt gaatgttagt
     3781 catcagcgac acgatagtga gaccacagcg gggacgaatt taacctggaa tacgcccgtt
     3841 gcaacgctta atggtagtta cagccagtcg tccaattata ctcagaccgg cggaagtatt
     3901 tccggtgggg ttgtagcctg gagtggcggg ttgaatttat ccagccggct ttcagatacc
     3961 tttgcgatta tgcaggctcc gggacttgaa ggagcctacg ttaacggcca aaaatatcgg
     4021 accaccaata aaaaaggaac ggtggtttat gacaacctta cgccatatcg cgaaaaccat
     4081 cttatgcttg atgtgtcgca aagtagcagt gaaacggaat tacgcggtaa ccgtaaagtt
     4141 gccgccccgt accgaggggc cgtcgtgcta gtgaattttg ataccgacca gcgtaaacca
     4201 tggtttatta aagcgcagcg tcctgatggc tcgcctctta tttttggtta tgatgtagta
     4261 gatcatcatg gtcataatgt gggcattgtt ggacaaggta gtcagctatt tattcgaacg
     4321 aatgatattc cgcccgaagt cagtgtacca gtagataaag agcaggggct ttcatgttca
     4381 atcacctttg gaaaaacggt tgatgaaagt aaagtttata tttgtcggta gtggtgaggt
     4441 ggtgaaatga aactctttct ttttatcgtg atgttattga ttttacctga aacatacgca
     4501 gcctgtacgg gagaaattac ttatcaggat aatttaatta ttcgtgagga ttttacgatt
     4561 aaccctaatc agtccgcaac ttatagccat aattttaacg atacaacttg ttcagggact
     4621 tataagataa cgcgtatgga tccttccgat atcatcgtgg gattatacaa tgatacagta
     4681 aaactgaagt taaaaatcgc ctgggcagat aataatactc tcacaatgcc gtttacaacg
     4741 ggctatacgg taacggttga acccgcttcc tctggggcga atgtaaatat ttctgccggt
     4801 agtgggaaca gtgtcctaat caacggggtg gtatcaataa caagcgcttc ttctgcaact
     4861 cagtttacgg ccagtttgcg gtttttaggg tgcctgctag caggaagagg ctggaatgcc
     4921 tgtgccgcag attataatag ttatcttaga ggtgcagggt tatattcatt tgatctgttt
     4981 gtgtcctacg atcgcaagca gacaacctgc aaacctgaag atctgacgat cacgctaccg
     5041 aatattgcgc tttctgaatt atataacaca ggcaaggtca gcaacaaaaa tgccgcggat
     5101 aatattcgac tccagtgtga taatcttttt ggtaatgcta aacaaacatc gcgtaaaatg
     5161 acggtttatc tctccagcag tgatttaata ccagatagct attctgtgtt gcgtggtgct
     5221 gtgaataatg gcgtcggatt tatactggag agcggtggaa aaacggtgaa tatttcaaat
     5281 acagcagagc agggtaatgc ttcaacgtta tggaaagtgg atcaagtagg cacgccgctc
     5341 aacagtgata tgataacaat ccctattatc gccagttatt atgtttatga ccgagacaat
     5401 ataaagccag gcgatctaaa agcgactgcg ctgatctatg tgaaatacga ttaatatata
     5461 tgaaaaacat ttaagatata tggcgcgata ggtgaatgaa cttccggtca cttacaataa
     5521 taagtgaccg ggatgacaat ctttctgcaa taaattctaa tgtggtatgc ggtagtttca
     5581 aaagggcgag atccagagcg aatcgggtag tgaaggcagt caacaaaaag gaggtttgaa
     5641 ggggatagag tgattaaggg ctaataaaaa agtaacatgg ggctgtattt ccccctctgg
     5701 atgagggggc tttttttatc gatgataaaa aatctcgcca tcataggctt tgatgatttt
     5761 tccatcggta tcgttaatca gtacatacgc gccgcccata taggtccagt gagtaccggc
     5821 atctggcgcg ggcagattac gtaatttcca ctgtttaata ttatactcat cggtgcggta
     5881 catttgcgga acggtatcgc cgggcttgaa gtgggtgaag tcggcgataa agctttttaa
     5941 ctcatattga tcaatgcccg ttgtcgcggg ggcggcccat gcaaaactgg ttgcaagcaa
     6001 cagcgcgcaa ggcagcaact tacttttcat acttttaccc tccacatatg cgggtcagtt
     6061 aacatcgtgt gtatcatttc tgctggtggc gtatctgaca agcgctattt tgttatctca
     6121 cgcccctttt cgtaaaaagt gtaaacgaaa gcgtcgtgca gcaacatatc cgccagcaag
     6181 tttgccagaa ccgaataggt tttgagaact atctgataac gctaaaatta tcgtccgccg
     6241 ctgactgtaa atttacattg tctggcacag acagtatgct taatagcgaa accccgctta
     6301 acacggtggg gcttgacgac tcggggtgcc cttctttgtg aaggctgaga aatacccgta
     6361 ccacctgatc tggataatgc cagcgtaggg aagtctgaca ctgctcgtgt cccttcttca
     6421 cgcgggcagg agctgaacca tgcagcctga cctgcactgc cgcacgcttg cggcgcatac
     6481 gttaaaacac tttcgcgcgc tctccccgct tacgcactgt atgacgaatg acgtcgtaca
     6541 aacgtttacc gccaatacgt tgctggcgct gggcgcttca cccgccatgg tgattgatcc
     6601 tgtcgaggcc agaccgtttg ccgccatcgc caacgccttg ctgattaatg tcggaacatt
     6661 aactgcctca cgcgctgacg cgatgcgtgc ggcggtagaa agcgcttatg atgccaaaac
     6721 gccgtggacg cttgatcctg tcgcggtggg cgcgctggaa tttcgtcggc gattttgcct
     6781 ggatctcttg tccctgcgcc cggcggcaat acgcggcaac gcctcggaaa tcctggcgtt
     6841 atccggcatg gcgctgggcg gacgcggcgt agataccacc gaggcggcgt tggccgcact
     6901 gcctgcggcg caggcgctgg cgcgtcagat agactgcatc gttgtggtta ccggagagat
     6961 agattacgtc actaatggtc agcgcacgct gagcattccc ggcggcgatc cgttaatgac
     7021 tcgcattgta ggcaccggct gcgcgttgtc ggcggttgtc gccgccagtt gcgcgttacc
     7081 gggcgccgcg ctggacaatg tcgcgtcggc ctgctgctgg atgaaactgg ctggacaggt
     7141 cgcggcagag cgtagcgaag gaccgggcag cttcatcccg gcttttcttg atgcgctcta
     7201 tcatctggat atggaggcgg ccaatgcaac gaattaacgc gctgacgatt gccggcaccg
     7261 atcccagcgg cggggccggt atccaggcgg atctcaagac cttttccgcg ctgggcgcat
     7321 atggctgttc ggtcatcacc gcgctggtgg cgcaaaatac ctgtggcgta cagtcggtgt
     7381 accggataga gccggacttt gtcgccgctc aacttgattc cgtgttcagc gatgtgcgca
     7441 ttgataccac aaaaatcggg atgctggcgg aaaccgatat tgtcgaggcc gtggcggagc
     7501 gactacagcg tcatcatgta cgtaatgtgg tgctggatac ggtgatgctg gcgaaaagcg
     7561 gcgatccgct gctctcgccc tctgcgatag aaacattacg cgtccggctg ttgccacagg
     7621 tatcgctgat tacgcctaat ttgccggaag ccgcagcgtt gctggatgcg ccccatgcac
     7681 gtacggaaca ggagatgctg gcgcaggggc gggcgttact ggcgatgggg tgtgaagcgg
     7741 tattgatgaa aggcgggcat ttagaggatg cgcaaagccc ggactggctc tttacccgtg
     7801 agggcgagca acgttttagc gcgccgcgtg tgaacaccaa aaatacgcat gggacgggct
     7861 gtacgctgtc ggcggcgctg gcggcgttac ggccccggca tcgctgttgg ggagagacgg
     7921 taaacgaggc gaaggcatgg ctttcggcgg cgctggcgca ggcggacacg ctggaagtgg
     7981 ggaagggcat tggtccggta catcatttcc acgcgtggtg gtagtatact gcctacagac
     8041 ccgtcgtcag gaaagataaa tggaacaagc gcatacccgg ctcatcgcgc aactgaatga
     8101 acgaatttca gcggcggata atacgccgct atacatgaaa ttcgcccaga cggtaaagga
     8161 tgccgtgcgc agcggtattc ttgagcacgg taatattttg cctggcgaac gcgatctcag
     8221 ccagcttacc ggcgtctcgc gcatcacggt acgaaaagcg atgcaggcgc tggaagaaga
     8281 gggggtcgtc acgcgcgccc gcggctacgg tacgcaaatc aataatatct ttgaatattc
     8341 cctgaaagag gcgcggggat tttctcagca ggttgtcttg cgcggcaaaa aaccggatac
     8401 gctatgggtt aacaaacgcg tggtaagttg tccggatgag gtcgcgcagc atctggcgat
     8461 ccccgcaggc agcgacgtct ttttactcaa acgcattcgt tatgttgatg aggacgcggt
     8521 atcgattgaa gagtcctggg tgcccgcgca tctgattcat gatgtcgacg cgattggcat
     8581 ttcgctgtat gactattttc gtcgccagca catttaccct cagcgtaccc gatcccgcgt
     8641 cagcgcccgg atgccggatg atgagtttca gtcgcatatt caaatggatg gtaaagtgcc
     8701 ggtgctggtg attaagcagg tggcgctcga tcagcagcag cggcctattg aatacagcat
     8761 cagttattgt cgtagcgacc tatacgtttt tgtgtgcgag gagtagcgcc tcgcgcgtgg
     8821 gcgcgcagtc gccgccgcga tgcccgacca cccagctcgc caccgcattt cccagcagta
     8881 cggcatccgc gagcgaccag cctgacgcca gtcctgccag cacgccgcca gcatggctgt
     8941 cgcctgcgcc gatggtatcc accacggttg ccggaaacgc tggcacaacg ccggaagatt
     9001 gcgcgctaaa ataccacgct ccgtctttat cgtggcgcac caccagcggc gcggaaaagc
     9061 gttttaccca tgcttcgccg aaagtgcggg tatcggtcgc aagcccggcg cgttccgcgg
     9121 cgatgatggc ttcctggcga ttgagggata cgatgggccg gcaggccata atgcgcgcca
     9181 ttgcatcgtc tgtaatatca ccgattcgcg ggccaaaatc gataaaaggc gttacatcgt
     9241 cgacggtttc cagccactgg atcagtggct cgccacagga cgaggccagt tgatagccgg
     9301 acaggtagac aagactgccc cgcggtgtcc tgagctgcga cagccagtcc gcattccact
     9361 ggttttccac gccgctaaaa gacataaacg tgcgttcgcc atccggttcg actaacgcca
     9421 gacaccagcc gttatctcct tcaaccgcgt caatcacgct ggataatccc tcttttgcca
     9481 gacggcggcg aatcctctcc gcccacacgc cctggcccag cggcagcgca ttgctggcgt
     9541 caatccccag tcgtttcaac gccacggcaa tattcagcgc acagccgccg acattgacgc
     9601 tctgttgttg cagttcaata tcgcctccgc gacgcggcaa cgtccaggcg tcggcaatga
     9661 tatcgatcac tgccgcgccg ataacggtga gcggacgccg ggtatgcagg gtcggtaata
     9721 atgtcagcaa ccgtgcgccg ttcatagtgc ctcccgccgt tgacgatagc tcgccagcgc
     9781 aacggcatag cgcgcaaaat ccagctgatt aaccttgtcc agcgtttgct ttaactgggg
     9841 gttaatggcg cttaccccgt gcaacgcgcc gcaaatggcg gtagccatcg cgccgatagt
     9901 gtcggtatcg ccgccgaggt tagcgcacag cacggcacag cggttaggat cggtattcgc
     9961 cagctccacc atggcgatag cgcagggaac cgattcaatg gtgctggttc ccgcgccgat
    10021 gatctgatag agctgttcgc tggcagattc gacgccgtcg gcgtggcgga caatgtttag
    10081 cgccagttcc agacgtgccg atagcgaggc gctaaacgtg gtaatacgcg ctgtctgcgc
    10141 ctgatgggcg atggcgggga gcgagtcggc aatactttgc cacgtgtcgc cgttaaccgc
    10201 tcgcgagacg gcccaggcga caaccacggc gccagccacc gccagatcgg atttatgcgt
    10261 cgggctggag gctaacgcta cttctgctat aaaggctgtc aggttagttg gcggcaacag
    10321 gcagcccaac ggcgaaacgc gcatggccgc gccgttagtc acgccgttat tttccagcgc
    10381 cgcgatgggt ttgccgtcgc gaatcgcatt cagcgcaatt tttgacgtcg ggccgagtac
    10441 atttttattg aacgcatcaa agcgttccgc ccaggcgagg atgttacgcc caataatctc
    10501 gggatcaatg ttgccttcgc attcgagtag cgcgtcggcc aggcagagcg ccattgcggt
    10561 atcgtccgta aactccgcgc ggttaaaata gcaggcggca ttattttctt ttgggccggg
    10621 cagaaagcgg tcaatccagc cgaaatgcgc tttgacgcgc gttctcggcc acagctcaga
    10681 gggcattccc atcgcatccc ctaacgcttg cccgtaaaga gcaccgagaa tacgttctgc
    10741 tttcatttta cttccccttg tgtcaacgca atatcgcgat cgtcaatagc agtgatctct
    10801 ttgtccgatt cgcgaaagaa aatcataaac agtagcgcga tgacggcaat catcactgcg
    10861 ccaaacgtcc acatgcccgc ccagttgaat gtcagaccgt taaccggttg cggataagca
    10921 aacatttttt ccatcatcac gccgccgaga cgatagccca gcaggctgcc gaatccctga
    10981 cagcagaggg tgataagccc ttgcgcagcg gtacgcatat gaaccggcgc ttttttatcg
    11041 acataaatgt aggcggtgac gtagtagaaa tcgtaactta cgccgtgcag caaaataccg
    11101 aggaacagca gggcgtaagt gaagtacgtc tccgcgccgc catagacaaa aaagccgtag
    11161 cggatcgcgg cggtaataag accaagtaat aatacctttt taataccaaa gcgcttagtg
    11221 aaaaagggta gcgccagcat aaagaagatt tcagagaact ggccgagcgt catccagccg
    11281 gtggcgtttt tcattcccac ttctgtcaga tagccgttag cgaagatgta gtagaaggcc
    11341 agcggcatcg caaacaggaa ggaacagaag aagaaaacga gaaagttttt atcgcgcagc
    11401 agaaccagcg catccagccc cagcatcact ttaatatcca tcttgccggt gctttttggc
    11461 ggcgtgtctg gcagacagaa cgcaaatacg cccagcaacg ctgaacttgc ggcggttatg
    11521 agcagtggaa tgttggtggg ggaaatatcg ttatagccta acatttgcgg caagaatcca
    11581 caggcgaggc cggaggcaat ccacccaatg gttcccataa cgcgaatgcg tggaaaatcg
    11641 cgttcaacgt ccggtacgtt agcgaaggca atgctgtttg tcagcgcgat ggtcggcata
    11701 taggtcaatg aataggccag gagcagcgga aagaatccgg caaaggtggt ttgctgtgcc
    11761 gcgaaataca tcagtacggc acccgcaaac atcagtaccg ccaggacttt ttgcgctgag
    11821 aaaaaacggt cggtaacgga gccgaccaga atcggcgaca ggatcgccgc aatggcggta
    11881 caggcataag accagcctat ttcaccggcg gaaaacccgc ttttatttag ccatagccac
    11941 agggggacga accaggcgcc ccagataaac cactccacga acatcatgaa cgacagttta
    12001 aaggtcgttt tcatttttga atccttcatg acaggtaagg tacgccacga caataccact
    12061 taataatacc ttttaaatac cattgagcat taattttgac cgatctaaca ctttttcgga
    12121 cgtgaatcga gtcagcagat agcgccgaaa aaatgcgcta aagttggcaa aaatggtcgg
    12181 tcagtaccag gcttattgcg acccgcaatc tgcggggcag gactattcac cttccgatac
    12241 cctatcggaa cttacgggag catagctatg actgatattg cgcagttgct tggcaaagac
    12301 gccgacagcc ttttacagca tcgttgtatg accattcctt ccgatcagct ttatctaccc
    12361 ggcaaggatt acgttgaccg ggtgatgatt gacaataatc gtccaccagc cgttctgcgt
    12421 aatatgcaga cgctctataa tactggacgc ctggcgggaa caggatacct ttcgatactg
    12481 cccgtcgatc agggagtgga gcactccgcc ggcgcttctt ttgcggccaa cccgcgctac
    12541 tttgacccaa aaaatattgt tgaattggcg attgaggccg gctgtaactg cgtggcctct
    12601 acctacggcg tactggcctc ggtttcacgg cgctatgcgc accgtattcc gtttttggtc
    12661 aaactgaatc acaacgaaac attgagctat ccgacagagt acgatcagac cctgtacgcc
    12721 agcgttgagc aggcgttcaa tatgggcgcc gtggcggtag gcgcgacgat ctatttcggt
    12781 tcggaacagt cccgtcgcca gattgaagag atctccgccg cttttgagcg tgcgcatgag
    12841 ctgggtatgg tgaccgtatt gtgggcttac ctgcgtaatt cttcctttaa aaaagacggc
    12901 gtcgattacc atgtatccgc tgacctgacg gggcaagcca accatctggc cgctacgatt
    12961 ggtgcggata ttgtgaaaca gaaaatggcc gagaataatg gcggttataa agcggtcaac
    13021 ttcggctata ccgacgatcg cgtgtacagc aaactgacca gcgataaccc gattgatttg
    13081 gttcgttacc agttggcgaa ctgctatatg ggacgcgccg ggcttatcaa ctccggcggc
    13141 gcggacggcg gtgacactga tctcggcgac gcggttcgta ccgcggtgat caacaaacga
    13201 gccggtggaa tgggactaat tctgggacgt aaagccttta agaaatcgat ggctgatggc
    13261 gtgaagttga ttaatgccgt acaggatgtc tatctggata gcaaagtcac catcgcctga
    13321 gttcaacgaa gaaaagccgg atgtgagcgc atccggccag cgactggtgt tattaacgta
    13381 gcaacgggca gtctggcggc agccgacagc gtaatgcgcc aggcagcacc tcaatatgaa
    13441 attcttgccc gctgagtggt tcgccatcca gattgaacgt gatttcatgc ggtgcatgaa
    13501 tatcaaacca cgctgaggcg ccgtcaataa tattcggatt gtcatctgac tgcgtgagtg
    13561 tggaaaacag cgccggcagc agttcttcgc cggtaaaaat ccgtagctgt aacagtccgt
    13621 cgttaatcag cgcggtggga cataattgct gcccgccgcc ggcctgacga ccgttgccga
    13681 tgccgatcac cagcgcatct ccctgccagt gaaagttttc gccacgtatt tcgcagcggt
    13741 caggggtcag cgtatccatt ctcatcagac cgtgaataag ataggagacg ccgcccaacg
    13801 cggctttaag tttttccggc gtttcggtgg taatgcgggt gccaaaaccg cccgtcgcca
    13861 tattgataaa acaggtttta tcattgaccc tggccatatc aatttccatc gcgtttccgg
    13921 caatcgccag tttcagcgct ttgtccagcg cttcaggaat accggcgctg gtggcaaaat
    13981 cgttggcggt gccgagcggc aaaaggccca gtgcgggggc tacgccgtcg cggatctgga
    14041 tgagcgcggt agacacttca ttaatggtac cgtctccgcc gccggcaatc accgtttcaa
    14101 cgcccagtct acgggcttca tcaacgtaac gctgcgcgtc gcctttttcc caggttaccc
    14161 gaacgtgaat ctgtatgcct tcgtcgcgaa gtagcgtaat ggcctcacgt agcggctggt
    14221 tatcagcgct tttgccattg aggatcagta agctggcggg aaagttagct atccgttatg
    14281 ccttaatagg ttgaacaaca atctccagaa agtgtatagc agaaatgaaa aagcgaggtc
    14341 agaacaggat gaaaattgaa acgttgcgca cttattgctt taccgttttt cttcctgctg
    14401 tacgcagcgg taagcgaagc atggtttaag gcaaatggcg acaagagaga tgccggtatg
    14461 cgcattgagt agcgcttgtg agagtgcaag gaaaccacaa ggggtagcca gacgctttcc
    14521 gatatagcgc ctttaataac gaaacggagg attaacaaga cgaacatacg tcagttatca
    14581 gtattaattt caaacaccac aatatcagat aaaaacctga tatttattac caaacatact
    14641 ttttaatagc ataaaatcga aatgttcttt agactgcttt ggcaggaaca agacgcacta
    14701 ttagcagtac actattcttg ttatcaaata aaacctattt agatgatgac ttagcgcagt
    14761 gtcttatagt cgtaccgttg cctgaggtat cgcttttctc ataaacataa acaggcatgt
    14821 gcatgaagag gtttatatga atgtcacttc aggcgtgaat gcgcaaacgc cattgctccc
    14881 cccttctgaa tggggtgatg acgaaaaacc ggtagctgaa atcgttgagt ttaacgctta
    14941 cggcaataaa cccagatgtt taatgtgcct gggaaccacg gcattgttta caggtgcttt
    15001 cagtggggta tgctcagggg ctgtcgccag tgtcagtagt ggtgctgcat atactaccgc
    15061 tctgacgatt ttaggcgcat cgtttggcat ggggggaatt ggtatgatgg gaatatgcgc
    15121 cggactatac cttagcgcaa atggcgtcag aacccggcca gcctggccat aaatgagcaa
    15181 acacagcaag tcatagggaa aagatgaatt ccggagatga cacggggtgt taagcgtcca
    15241 gaccagaggc ttatgactta tatagaaacg ctttagatag agtatggggt gttatgtatt
    15301 caagagccga tcgcttatta agacagtttt cactgaaatt aaatgccgat tcaattgcct
    15361 ttgacgaaaa cagattatgc tcatttatta tagataaccg ttaccgtatc ttactaacaa
    15421 gcactaacag tgagtatata atgatatacg gtttttgcgg aagacctccg gataataata
    15481 atcttgcttt tgaatttctc aattctaatt tatggtttgc agagaataat ggaccacatt
    15541 tgtgttatga taataactca caatcattat tactggctct aaatttctca ctcaatgaaa
    15601 gttctgtaga gaaacttgaa tgtgaaattg aggtggttat tagatcaatg gagaatctgt
    15661 atcacatttt acaggataaa ggaataaatc tggataccga ttatacgtga cggtgggaag
    15721 ggtgtttggt gatctggtgg taatagagga taatcaaccc cagcaaaact tacatggcct
    15781 gatgaagatg gactgagcgt aggtgcgatg gtttgagtat tactttgaca tgaaatcaaa
    15841 cctctaatcc gggaaaacat tattttaatc cttgtaaaag cggcattaaa acgtgccata
    15901 actttacacg cttaaattat cagtttttaa ccttaattta ataacctgga aactttttgt
    15961 gtaagtactc acaaagcagt tattgattta attcactgat tttaaacgta aacgtcagaa
    16021 tgctaagtcc tgagtctgac cagatgcagg gaggattgtg acttgctggc tggccatgaa
    16081 taggggaggt ctctaaacct aagcgcccat ttgcgctttg gttagtgtgg tcaattttcg
    16141 gatgtggcgg gaagtaccac ttttttattg attatacgca aaaaataagc ctgcgtaagg
    16201 gagattacgc aggccaagga ggtggttcct ggtacagcta gcatttatgg gttatgtttt
    16261 tcagcgcgtt gaataatacc cgcattgagc gaagcggtat gtgatcaatt tctaagaatc
    16321 ttcccgccat gaaaaaataa ccgcaattaa ctacttagca tgggggttac gcgttgattc
    16381 gcctgagaaa ttacgcatca atagtgcgta atccagcgta acgtcctgcg ggacgggcat
    16441 ccagacggta tagccatcgc caggcgccac cggcatagcg tcgcctttgg cgttctccat
    16501 ctgttccaga gtgaaattga tatttccctg cggagtcatc agctccagac tatcgccaac
    16561 ggagaattta ttcttcaccg ccacggccgc cagttggcct ttacgctcgc cggtgaactc
    16621 gccgacaaat tgctggcgtt cggaaacgga gtacccgtac tcgtaattct ggtaatcgtc
    16681 gtgcgtatgg cgacgcagga aaccttcggt atagccgcga tgagccagac cttccagcgt
    16741 ttccagcagc gtagggtcga agggtttacc cgcggcggcg tcgtcgatgg ccttacggta
    16801 gacctgggcg gtacgggcgc agtaataaaa ggatttggtg cggccttcga ttttcagcga
    16861 gtggacgccc attttcgtca ggcgctccac gtgggcgata gcgcgcaaat cttttgagtt
    16921 catgatatag gtgccatgct cgtcttcgaa cgcggtcatg tattcgcccg gtctttgggc
    16981 ctcttctatc ataaacactt tatccgtcgg cgcgccgata ccgagcgtcg gctcaacgtt
    17041 ctgtaccgga atcggttcat gcttatgcac gatgttgccg acaacgtctt cttttccttc
    17101 ctgcacgtta tattcccaac ggcaggcatt ggtgcaggtg ccctggttcg gatcgcgttt
    17161 attgatgtag ccggaaagca ggcagcgacc ggaataggcc atgcatagcg cgccgtggac
    17221 gaaaatttct atttccatat ccggcacctg ctggcgaatt tcctcaatct cttccagcga
    17281 cagctcgcgg gagagaatca cgcgggtcag ccccatctgc tgccagaatt ttaccgtcgc
    17341 ccagtttacg gcgttagcct gtaccgacag gtgaatcggc attgccggga agtgctcgcg
    17401 taccagcata atcaaccctg gatcggacat gatcagcgca tccgggccca tctcgacgac
    17461 gggtttcagg tcacggataa aggttttgag cttggcgtta tgcggggcga tgttcaccac
    17521 cacgtagaat ttttttccga gcgcgtgggc ttcgttgatg ccaagctgca aattttcgtg
    17581 attgaattcg ttattgcgca cgcgtaaaga gtaacgcggt tggcccgcat agacggcatc
    17641 ggcaccgtaa gcgaaagcgt aacgcatatt tttcagcgtt cccgctggcg aaaggagttc
    17701 tggtttaaac atcattttct cgttctgatg acaggtcaga tccgcctcac ctgatgaggc
    17761 ggctggaaga gagtcctcac tttaagggcg ggcattgtac gcttacggac aggccgagta
    17821 aatattgcga gagtatattg gcgctaatag aacaccggat gttaatgggg agccaatgat
    17881 gaaaatgagc cgcacggcca tcgcgctgag tttgctggga atggccgcgc atcccgtttg
    17941 tgccgctccg tcgtttgaag agacggcgag acaggtgatt atcgcttttc agcagcgaga
    18001 caacgcgaaa attaatgccc tgattgataa aaaagtcggg atgtatgtgc tgtaccgaat
    18061 tggggctggg tttgattata aatggatgaa aaaatttgat attaataaac cgatacctga
    18121 ctttaactac ctgttggggc aggtaggttg gttttcagag catattcctg tggataagga
    18181 atttgatcac cacacggagg ttgagtacgt ttgtgaaaag ggatgggatc acgccggttt
    18241 ttttgtcagc tataccggtt ctgataatgc gctgctgacg tttagcatgg tgaatggagc
    18301 ggatagtggg gatcaggcgt cggatacccg tatagcaaac gccaggcggc ttgagctgca
    18361 atcagagcga gtggtggcag tgccgaaaga atggggtgat ggtttgattt ttcatctgag
    18421 cgagcttcat ggcttgggca aagggtggag tttaacgctg ctggatttgg tcacggaaga
    18481 ttgtagtgcg tgaggcatat atgtttaatc agggtaaatg gctgcttatt tatatctttc
    18541 tgctatcagg atgttatggc accccctcaa tattcagaat ttaaataaag catttcctga
    18601 atatgaaact aattcactaa aaaataaagg tgaaatcacc tcggcaacat gcattaaaga
    18661 aaatacaaaa ggtcatttga cttattatag cgtcagcgat cccgtcttta actaattcgg
    18721 gtcacgttat gtatccacta tggggaatct ttatatattc cgaaaaaaaa acacaatgat
    18781 attcttaatg cagataagag agtaatctta gggtgtgcag gtttgtaaac cag
//
LOCUS       DAJVKX010000083        18584 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000083 DAJVKX010000000
VERSION     DAJVKX010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18584
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.083"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..586)
                     /gene="rsmG"
                     /locus_tag="OPY25_002978"
     CDS             complement(<1..586)
                     /gene="rsmG"
                     /locus_tag="OPY25_002978"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462772.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCS0928540.1"
                     /translation="MLNKLSRLLADAGISLTDHQKTLLVAYVDMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGQRFIDVGTGPGLPGIPLAIVLPDAHFTLLDSLGKRV
                     RFLRQVQHELKLENITPVQSRVEAYPSEPPFDGVISRAFASLNDMVSWCHHLPGEKGR
                     FYALKGQLPGDEIASLPDNFNVESVEKLRVPQLEG"
     gene            complement(689..2578)
                     /gene="mnmG"
                     /locus_tag="OPY25_002979"
     CDS             complement(689..2578)
                     /gene="mnmG"
                     /locus_tag="OPY25_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCS0928541.1"
                     /translation="MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPTIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFKILNASKGPAVRATRAQADRV
                     LYRQAVRIALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNAFQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIHGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     MGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAESADEVNAHLTTPLSREAS
                     GEDLLRRPEMTYAQLTSLAAFAPALEDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(2957..3400)
                     /gene="mioC"
                     /locus_tag="OPY25_002980"
     CDS             complement(2957..3400)
                     /gene="mioC"
                     /locus_tag="OPY25_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HCS0928542.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEAAGFSTETVHGPLLEDL
                     STSGIWLIISSTHGAGDIPDNLTPFYEDLQTQKPDLSAVRFGAIGIGSREYDTFCGAI
                     EKIEAELKGAGAKQVGETLKINILEHEIPEDPAEIWLGSWINLLK"
     gene            complement(3490..3948)
                     /gene="asnC"
                     /locus_tag="OPY25_002981"
     CDS             complement(3490..3948)
                     /gene="asnC"
                     /locus_tag="OPY25_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HCS0928543.1"
                     /translation="MENYQIDNLDRGILDALMENARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALARLESLDEVTEAYYTT
                     GHYSIFIKVMCKSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            4099..5091
                     /gene="asnA"
                     /locus_tag="OPY25_002982"
     CDS             4099..5091
                     /gene="asnA"
                     /locus_tag="OPY25_002982"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HCS0928544.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAEVHKQFGLAPF
                     LPDQIHFVHSQELLARFPDLDAKGRERAIAKELGAVFLVGIGGKLSDGRRHDVRAPDY
                     DDWSSASELGYAGLNGDILVWNPVLEDAFELSSMGIRVDADTLMRQLALTGDEDRLQL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAQVRESIPAIL"
     gene            complement(5096..6547)
                     /gene="viaA"
                     /locus_tag="OPY25_002983"
     CDS             complement(5096..6547)
                     /gene="viaA"
                     /locus_tag="OPY25_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HCS0928545.1"
                     /translation="MLTLDTLNTMLAVSEEGMVEEMILALLASPQLVIFFEKFPRLKN
                     AVTADLPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILALLHRL
                     HSPYAAQAKQLTESNSTFTPALHTLFLQRWRLSLVVQATTLNQQLLEEEREQLLSDVQ
                     ERMTLSGQLEPTLAENDNAAGRLWDMSAGQLKRGDYQLIVKYGEFLAAQPELMQLAEQ
                     LGRSREAKSVPKKDAPMETFRTLVREPATVPEQVDGIQQGDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGEAWREKVTERPVVHQDVDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRVALADNRRCFIMLFSTDVVRYELSGPESIEQAIRFLSQRFRGG
                     TDIASCFRAIIERMQGREWFDADAVVISDFIAQRLPDDVVSKVGELQRLHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(6541..8037)
                     /gene="ravA"
                     /locus_tag="OPY25_002984"
     CDS             complement(6541..8037)
                     /gene="ravA"
                     /locus_tag="OPY25_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HCS0928546.1"
                     /translation="MAHPHLLAERISRLSSALEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQRARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTT
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERHFRNGAFEEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLVSQQDESDNPVPASLQVSDEEYQQWQKD
                     IGAISLPDPVFELIFTLRQQLDNLPNAPYVSDRRWKKAIRLLQASAFFSGRDAVAPID
                     LILLKDCLWYDAQSLNLMQQQLEILMTGHAWQQQAMLTRLGGIVQRRLQLQQQQSDKT
                     AFTVIKEGGMFSRRPHYTLPPEASASTLTLLLQKPLKLHDMEVIHITFDRSALELWLT
                     KGGEIRGKLNGIGFAQTLNMEVDNAQHPVVRDISLQGTRLALPGAAEDSMPAEIKQQL
                     ETLENDWRQQHTRFSEQQHCLFIHSDWLGRIEASLQDVGEQIRQAQQC"
     gene            8385..10253
                     /gene="kup"
                     /locus_tag="OPY25_002985"
     CDS             8385..10253
                     /gene="kup"
                     /locus_tag="OPY25_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HCS0928547.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTGMVGKLFAPIMLTWFLILAVLGLRSIIANPEVLHALNPVWAVRFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKHPEAIKNP
                     FFLLAPDWALIPLLILAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWLLYFAVVVVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARKNWHW
                     NKYFVALILIAFLCVDIPLFSANLDKLLSGGWLPLSLGLIMFTIMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRALSVIPFALLHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETLNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLIVGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            10470..10889
                     /gene="rbsD"
                     /locus_tag="OPY25_002986"
     CDS             10470..10889
                     /gene="rbsD"
                     /locus_tag="OPY25_002986"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCS0928548.1"
                     /translation="MKKGTVLNSEISSVISRLGHTDTLVVCDAGLPIPNSTARIDMAL
                     TQGVPSFMQVVDVVTWEMQVEAAILATEIKQQNPQLHETLLTHLEQLQQHQGNTIKIS
                     YTTHEQFKKLTADSQAVIRSGECSPYANVIICAGVTF"
     gene            10897..12402
                     /gene="rbsA"
                     /locus_tag="OPY25_002987"
     CDS             10897..12402
                     /gene="rbsA"
                     /locus_tag="OPY25_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HCS0928549.1"
                     /translation="MDALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGSLLWLGKETTFNGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKKMYAEADHLLAKLNLRFKSDKLVGELSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETDSLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVATLTEDSLIEMMVGRKLEDQYPHLDNAPGEIRLKVDNLCGPGVNDVSFVLR
                     KGEILGISGLMGTGRTELMKVLYGAMPRTSGYVTLEGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALDYFSRAGGSLKHKDEQQAVGDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            12408..13373
                     /gene="rbsC"
                     /locus_tag="OPY25_002988"
     CDS             12408..13373
                     /gene="rbsC"
                     /locus_tag="OPY25_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HCS0928550.1"
                     /translation="MTTQAVSGRRYFTKAWLLEQKSLIALLVLIAIVSTLSPNFFTVN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGVEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTDGSPVNTGFTDNADL
                     FGWFGIGRPLGVPTPVWIMAIVFIAAWYMLHHTRLGRYIYALGGNEAATRLSGISVSK
                     VKIIVYSLCGLTASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            13398..14288
                     /gene="rbsB"
                     /locus_tag="OPY25_002989"
     CDS             13398..14288
                     /gene="rbsB"
                     /locus_tag="OPY25_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HCS0928551.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVISTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQAKIPVITLDRQATKGDVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKADVMVVGFDGTPDGEKAVKDGKLAATIAQLPDQIGAKGVEVADKV
                     LKGEKVQAKYPVDLKLVIKQ"
     gene            14421..15350
                     /gene="rbsK"
                     /locus_tag="OPY25_002990"
     CDS             14421..15350
                     /gene="rbsK"
                     /locus_tag="OPY25_002990"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCS0928552.1"
                     /translation="MKTAGNLIVLGSINADHILNLESFPTPGETVTGSHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDDIGDSIRKQLVSDRIDIAPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVDAQRERIAQADALLMQLESPLESVLAAAKIAHQHH
                     TTVALNPAPARELPDELLALVDIITPNETEAEKLTGVRVENDDDVAKAAQVLHDKGIR
                     TVLITLGSRGVWASVNGEGRRVPGFSVEAVDTIAAGDTFNGAFITAILEETPLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIEAFLHQQG"
     gene            15354..16352
                     /gene="rbsR"
                     /locus_tag="OPY25_002991"
     CDS             15354..16352
                     /gene="rbsR"
                     /locus_tag="OPY25_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HCS0928553.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSETITEKVEAAIKSLN
                     YAPSALARSLKLNQTRTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMERYPSIPTVMMDWSPFDGEGDSDLIQ
                     DNSLLGGDLATQHLIDKGFTRIACITGPLDKTPARLRLEGYRAAMKRAGLAIPQGYEI
                     TGDFEFGGGFDAMQALLAHQQRPQAVFTGNDAMAVGAYQALYQAGLRIPQDMAVIGYD
                     DIELARYMTPPLTTIHQPKDELGELAIDVLIHRMAQPALQQQRLQLTPVLTVRGSV"
     gene            complement(16318..17745)
                     /gene="mdtD"
                     /locus_tag="OPY25_002992"
                     /pseudo
     CDS             complement(16318..17745)
                     /gene="mdtD"
                     /locus_tag="OPY25_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462786.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
     gene            complement(17757..18461)
                     /locus_tag="OPY25_002993"
     CDS             complement(17757..18461)
                     /locus_tag="OPY25_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCS0928554.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGDYAPGTILPGEIELG
                     EQYGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQGNWNFLDQELLTWWMTEENFHQ
                     VVDHFLVMRISLEPQACLLAATLGTPEQKARLNALMEEMVALKKHFKRERWIEVDMAW
                     HEHIYEMSANPFLISFATLFHSVYHTYFTSITYNEVVKLDLHQAIVDAIADGDGERAF
                     QACQALLIAPNERPDN"
BASE COUNT         4261 a         4769 c         5090 g         4464 t
ORIGIN      
        1 cgccttccag ttgcggaacg cgtaattttt caacagattc gacgttaaaa ttgtcaggta
       61 gtgaggcaat ttcatcccct ggcaattgcc cttttaaggc ataaaaacgt cctttctctc
      121 ccggcagatg gtgacaccag ctcaccatat cattcaacga tgcgaaagcg cggctgataa
      181 cgccatcaaa cggcggttcg gagggatagg cttcaacgcg gctttgaacc ggcgtgatgt
      241 tttccagttt cagttcgtgc tggacctgac gcagaaaacg tacccgcttg cccaggctgt
      301 cgagtaaggt gaaatgcgcg tcagggagaa caatagccag cgggatgccc ggcagccccg
      361 gtcctgttcc tacatcgata aaacgctgtc cctgcagata cggcgcaacg actatgctgt
      421 cgagaatatg gcgtaccaac atttcgttgg gatcccgcac tgacgtcagg ttgtatgctt
      481 tgttccattt gtgcagcata tcaacgtagg cgaccagcag cgttttctgg tgatcggtaa
      541 gagaaatacc ggcatcagcc agcagacgag agagtttgtt gagcacggtc attacctgtt
      601 aataatcaaa tgcccgatgc gctttcgctt atcgggccta caaatttgta gggcgggcaa
      661 gcgaagcgcc cccgccaaat tagtgttatc aagcgctacg acgcagcata ccttgttttt
      721 tcagccatac cagcagaatg gagattgccg ctggcgtaac gccggagata cgcgatgcct
      781 ggccgataga cgccggttta tgatcgttca gcttggcgat aacttcgttc gacagaccgg
      841 aaacctgacg ataatccagc gtggcaggca gcaacgtatt ctcgttacgt agttgttttt
      901 caatctcatc ctgctggcga gcgatatagc cttcgtattt gacctggatt tccacctgtt
      961 cagcggcttg ctcatcttca agcgcaggcg cgaatgcggc aagcgaagtg agctgcgcat
     1021 atgtcatttc cggacgacgc aacagatctt cgccgctggc ctcacgggag agtggcgtgg
     1081 tcaaatgcgc attcacttca tcagcggatt ccgcagacgg cgttacccat gtcgatttca
     1141 gccgctgacg ttcgcgttcg atattttcca gcttctcgtt gaagcgcgcc cagcgttcat
     1201 catccaccag acccagctcg cggcccattt cggtcagacg cagatcggcg ttgtcctcac
     1261 gcagcatcag gcgatattcg gcgcgggagg taaacatgcg atacggctct ttggtgccca
     1321 gcgtacagag atcgtccacc agcacgccga gataagcctg agaacgcgca ggcgcccagc
     1381 cctctttgtc ggcggaaaga cgcgcggcat tcagaccagc gagcaagccc tgcgccgcag
     1441 cctcttcata gccggtagta ccgttgattt gaccagcaaa gaacaggccg tgaataaatt
     1501 tactttccag agtcggtttc agatctcgcg ggtcgaagaa atcatactca atcgcgtaac
     1561 cagggcgaac gatcttcgcg ttctccatgc cctgcatgga acggacaatc tgcatctgca
     1621 cgtcaaacgg caggctggtg gagataccgt tagggtaaat ctcgttagag gtcagtcctt
     1681 ccggctcaag gaagatctga tgctggttac gatcggcaaa acgcatcacc ttgtcttcga
     1741 tcgaaggaca gtagcgtggg ccgatccctt cgatcacgcc agcgtacatt gggctacgat
     1801 cgaggttatt acgaatcacg tcatgggttt tctcattggt atgcgtgatg taacacggca
     1861 cctgttgcgg atgctgaaaa gcattcccca taaacgagaa aaccggcatc gggttatcgc
     1921 catgctgttg agccaacacg ctgaaatcga tagtacgcgc atcaatacgc ggcggtgtgc
     1981 cggttttcag gcggctgacg cgtagcggaa gctcacgcag acggcgagac agcgggatgg
     2041 atggcggatc gccagcacga ccgccgctgt agttatccag accaatatga attttgccgt
     2101 ccaggaaagt cccgacggtc agcaccaccg ctttcgcgcg gaatttgagc cccatttggg
     2161 tcacggcgcc gacaacgcga tcgttttcga caatcagatc ttcaaccgct tgctggaaga
     2221 tcatcagatt cggctgattc tccagcgcga tacgtaccgc ctggcgatat aagactcgat
     2281 ccgcctgagc tcgggtagcg cgaacggccg gacctttgct ggcgtttagt atcttaaact
     2341 gaatacctgc ctgatcgatc gctttcgcca tcagaccgcc gagcgcatcc acctctttta
     2401 ccagatgtcc cttgccaata ccgccgatcg tcgggttgca gctcatctgc cccaacgtgt
     2461 caatattgtg tgtcaaaagc agagtctgtt gacccatacg cgctgcggcc atcgcggcct
     2521 cagtgcctgc atgacccccg ccaataataa tgacgtcaaa aggatcctga taaaacatgg
     2581 taattgcctc gcataacgcg gtgtgaaaat ggattgaagc ccgggcggtg gattctactc
     2641 aactttagcc gatggagaaa gccccgggat ccgggctatt aaaaagaaga tctttttatt
     2701 tagagatctg ttctattgtg atctcttatt aggatcgcac caggctgtgg ataacccgga
     2761 tcctgtaata aagatcaatg cgttggaaag gatcactagc tgtgaatgat cggtgatcgt
     2821 ggcccgtata agctgggatc aaaacgggta cttatacaca actcaaaaag tgaacaaagg
     2881 ttattctttg gataactacc ggttgatcca agcttttcac catatttatc cacaatagat
     2941 cgcacgatct ttacacttat ttgagtaaat taatccagga tccgagccaa atctccgctg
     3001 gatcttccgg aatctcatgt tcaaggatgt tgatcttcag tgtttcccca acctgttttg
     3061 cgccagcgcc tttcagttcc gcttctattt tctcaatcgc gccgcaaaac gtgtcgtatt
     3121 ctcgactgcc aatgccaatt gcgccgaaac gtaccgcgga aagatcgggt ttctgcgtct
     3181 gaaggtcttc atagaaaggg gtcaggttgt ccggaatgtc tccggcgccg tgcgttgagc
     3241 tgattatcag ccagatcccg gaagttgaca gatcctctaa taacggaccg tgcaccgttt
     3301 cggttgaaaa accggcagct tccagctttt ccgccagatg ttccgcgacg tattcggcgc
     3361 cgcccagggt gctgccgctg ataagagtaa tgtctgccat tgatcgctcg ctcaggtaaa
     3421 gaggctgcat tgtactctgt gaacgagctg ggatctacct gtggaaaaat gtgggattaa
     3481 aaaagccgat catggcttga tggtgcgcat gatcgggttc tgcaagacga tcagtgtctc
     3541 agtggactga atttcatcaa ttgtttggat cttgttgata agtacgtgct gaagcgcgtc
     3601 aattgatttg cacatcactt ttataaagat gctgtagtga ccggtggtgt aatacgcttc
     3661 cgtcacctca tccaggcttt ccagccgggc cagtgcggag ggatagtctt tggcgctttt
     3721 gaggatgatg ccaataaagc agcctacatc gtagcccagt tgtttagggc tgacgtcaat
     3781 ccgtgcgccc gtaatgatcc cggcctgctt cattttctcg acgcgaacat gaatggttcc
     3841 agggctaacg ccaaattgtt tggccagttc ggcgtaggcg gtgcgggcat tttccattaa
     3901 ggcgtcaagt atgccgcggt ccagattgtc gatctgataa ttttccatcg ctttttctta
     3961 tgcagattaa tgattatctc tattttagcc attattttta acgaatcaaa atcgaagtta
     4021 gctttttatc tgttgattat tgaatagtgc tctcgttttg ttgcttaatc ataggcaaca
     4081 ggacgcagga gtaaaaaaat gaaaaccgct tacattgcca aacaacgtca aattagcttc
     4141 gtgaaatcac atttctctcg ccagctagag gagcgtctgg gtctgattga ggtccaggcg
     4201 ccgatcctga gtcgcgtagg ggatggtacg caggataatt tgtccggctg tgaaaaagcg
     4261 gtgcaggtaa aagtgaaagc gttgcctgac gcccagttcg aagtggtgca ttcactggcg
     4321 aagtggaaac gtcaaaccct ggggcaacat gacttcagcg cgggcgaagg gctgtacacg
     4381 cacatgaaag cccttcgccc cgatgaagac cgactctctc cgctccactc ggtctatgtg
     4441 gatcagtggg actgggagcg tgtcatgggc gatggcgagc gccaattttc caccctgaaa
     4501 agcacagtag aggctatatg ggcaggcatt aaggcgacgg aagcggaagt gcataaacag
     4561 tttggtctgg cgccgttcct gccggatcag atccattttg ttcacagtca ggaactgctg
     4621 gcgcgtttcc cggatctgga tgcgaaaggg cgcgaacgcg cgatcgccaa agaacttggc
     4681 gccgttttcc tggtggggat cggcggtaaa ctgagcgatg gccgccgcca tgatgtacgc
     4741 gcgccggatt atgatgactg gagctccgca tctgagctgg gctacgctgg tctgaacggc
     4801 gatatcctag tgtggaaccc ggtgctggaa gatgcgtttg agctttcctc tatgggtatc
     4861 cgcgtagatg ccgatacgct gatgcgtcag ctggcgttga ccggtgatga agatcgcctg
     4921 caactggagt ggcatcaggc gctgctgcgc ggcgaaatgc cgcagaccat cggcggcggg
     4981 attgggcagt cgcgtctgac gatgttgctg ctgcaattgc cgcatattgg tcaggtgcag
     5041 tgcggcgtat ggcccgcgca ggttcgcgaa agcattcctg ctattttata agccgttagc
     5101 gtcgccagcg tctcagcagg cggcttcgca tcccggtgtc aaagcgccag atatgatcga
     5161 aaatgcgcat gatgccgggt ttgccgtgcg ccgacatcgc caccgcatgg aatcgatgct
     5221 ggtgaagacg ctgcaactct cccactttgc tcaccacgtc atccggcaag cgctgggcga
     5281 taaaatccga aatgaccacc gcatcggcat caaaccattc ccgtccctgc attctttcaa
     5341 taatggcgcg aaaacagctg gcgatatccg tgccgccgcg aaaacgttga cttaaaaagc
     5401 ggatggcctg ctcaatactt tccgggccgg agagttcata acgcacaacg tcagtggaaa
     5461 acagcataat aaagcagcgg cggttatccg ccagcgcaac gcgcatcaac gccaggcaga
     5521 acgcttttgc gcactgctcg ttaaatcctc ccatcgagcc tgaagtatcg acgcagacaa
     5581 taaacggtcc gcgcggctgc tcgtcgacat cctggtgtac taccggccgt tcggtcactt
     5641 tctcacgcca cgcttcgcca tgcaggcgat aggtgaggag ctgtttttcc actaaccggc
     5701 ggtaaaattc atattccagc tcggtgatgc cgagcgtcgc cagctctggc ggcaacaggc
     5761 gcagaatatc atcgccttgc tgaataccgt caacctgctc cggcaccgtt gcgggttcgc
     5821 gtaccagtgt acgaaaggtt tccatcggcg cgtctttttt cggtaccgat ttggcttccc
     5881 gcgaacgtcc cagttgttcc gccagttgca ttagctccgg ctgggcggcg agaaattcgc
     5941 cgtattttac gatcagttga taatcaccac gtttaagctg gcccgcgctc atatcccaca
     6001 ggcggcctgc ggcattatca ttttccgcca acgtcggttc cagttgcccg ctcagcgtca
     6061 tccgttcctg tacgtcactc agcaactgct cgcgctcttc ttccagtagt tgctggttta
     6121 acgtggtggc ctgcacgacc agacttaacc gccagcgttg caaaaaaagc gtgtgtagcg
     6181 caggggtaaa ggtactgttg ctctccgtca actgcttcgc ctgcgcggca tacggtgaat
     6241 gcaggcgatg aagcaacgcc agtatttgcg gcagttgcac gatgaactgt ggggtagaga
     6301 gaagttggct ttgctgataa cacatgacct cttccgtgag ttccggcgga acgcgtgcgt
     6361 ctttaagacg gctgcgtagc gcttcccgcc agcgcgggag atcggcggtc acggcgtttt
     6421 ttaaacgtgg aaacttttca aagaaaatga ccagctgtgg ggaagccagt agcgcgagga
     6481 tcatctcttc gaccattccc tcttcgctga cggccagcat ggtatttagc gtatccagcg
     6541 tcagcattgt tgcgcctggc ggatctgttc tcctacatcc tgcaggctgg cctcaatgcg
     6601 ccctaaccag tcgctgtgaa taaacaggca atgttgctgc tcgctgaagc gggtatgctg
     6661 ctggcgccag tcgttttcta acgtttccag ctgctgtttg atctccgcag gcatactgtc
     6721 ttcagccgct cccggtaacg ccagacgggt accttgtaga ctgatgtcgc gcaccaccgg
     6781 atgttgagcg ttatcgactt ccatattcag cgtttgggca aagccgatcc cgttcagttt
     6841 gccgcggatc tcgccgcctt tggtcagcca aagttccagc gcgctgcggt caaaggtaat
     6901 atggatcact tccatatcat gcagttttag cggtttttgt agcaataacg tcaacgttga
     6961 cgcactggct tccggcggta aagtgtaatg cgggcgacgg ctgaacatac cgccttcttt
     7021 aatgacggtg aaggcggttt tatcgctttg ctgttgctgc aactggaggc ggcgctggac
     7081 gataccgccg aggcgagtca gcatggcctg ctgctgccag gcgtgtccgg tcatcaatat
     7141 ttccagttgc tgttgcatga gattcagact ctgcgcgtca taccacaagc aatcttttag
     7201 caggataagg tcaatcggcg caaccgcgtc gcgtccgcta aagaaggcgc tggcctgtaa
     7261 caggcggatg gctttcttcc agcgacggtc ggagacataa ggcgcattcg gcaaattatc
     7321 cagctgttgg cgcagagtaa atatcagctc aaagaccgga tcaggcagtg aaatcgcgcc
     7381 gatatctttt tgccactgtt gatattcttc gtcgctaacc tgtaacgagg cggggaccgg
     7441 gttatcactc tcatcctgct gactaaccag catggagcgg aaattggctt tatcctgaac
     7501 tttatccagc cacaggcgaa tcaacattcg gtcgtacaag gcttccaggc tgctgtccgc
     7561 ttcgggcagt tcgttagagg ccgccaccag tagccgcatc gggatttttt cctcaaacgc
     7621 gccgttgcgg aaatggcgtt cgttaatggc ggtcagcaat gtgttcagga tagcgggccc
     7681 ggctttccag atttcatcca gaaaaacgat ttcggcttcg ggaaggtagc cggtcgttaa
     7741 gcgttcatag cgaccttcat ctttcagcgc ctgaatagag agcgggccaa acacctcttc
     7801 cggcgtggaa aagcgtgtca tcagatattc aaaagcgcgg gcgcgctgga aagcaaactt
     7861 caggcggcgg gcaatcagac tcttggcgat accgggcggg cccaacaaaa agacgctctc
     7921 accgcttaac gccgccagta ggcacaggcg tatggcgtga ctacgttcat acagcccctt
     7981 ctcaagggcg ctgctcagac gggaaattct ttccgctaat aaatgtgggt gagccataat
     8041 aaagaggcgt cctttcgaca aatggatcat gctaattgcg agtatagacg tttcaccacc
     8101 ggggctgtaa tcttctgacg cgctgtttat ttttctttga gccaggttaa tctggcttca
     8161 tttaggggta cgattttatg attaatcgtg catactgtgc gcttttttgt gggccaaggg
     8221 actaagcaca catttcatat ctatacactc attcattcaa actacatcaa ggcggcaaag
     8281 gagtgaatcc cctggcactg acttaaacgt gtgactgggg taagcgaatg cagtcgacaa
     8341 ggaggtagcg tgaagggtga cgtgtataaa cgaaagatga gtctatgagc actgataata
     8401 agcaatcgtt gcctgcgatt accctcgcag ctattggggt tgtctacggt gatattggta
     8461 ccagcccgct ttatacgctt cgtgaatgtt tgtccggtca gtttggtttt ggcgttgaac
     8521 gagatgccgt gtttggtttt ctgtcgctga tcttctggct actcatcttt gtggtttcca
     8581 tcaaatatct caccttcgtg atgcgcgccg ataacgcggg tgaaggtgga attttgacgc
     8641 tgatgtcgct tgccgggcgt aatacctcgg cgcgcaccac atccatgtta gttatcatgg
     8701 gactgatagg cggcagcttt ttctatggcg aagtggtcat tacgccggcg atttcggtga
     8761 tgtcggcgat tgaaggcctg gagattgtcg cgccgcagct ggatacctgg attgtcccgc
     8821 tctccattat tgtgctgact ctgttgttta tgattcagaa gcacggtacg ggaatggtag
     8881 gaaaactctt tgcgccgatc atgctgacct ggtttttaat cctggcggta cttggcctac
     8941 gcagtattat cgccaatccc gaagtgttac atgcgctgaa tcctgtctgg gcggtacgtt
     9001 ttttccttga atataaaacc gtatcgttta ttgcgttggg cgcggtggtg ctgtcgatta
     9061 ccggcgtaga ggcgttgtac gccgatatgg gacacttcgg taagttcccg attcgcctgg
     9121 cgtggtttac cgtggtattg ccgtcgttag tactgaacta ctttggtcag ggtgcattgc
     9181 tactaaagca tccggaagcg attaaaaacc ccttcttcct gttggcgccg gactgggcgt
     9241 taattccgct gctgattctg gccgcgctgg cgacggtgat cgcctcccag gcggtaattt
     9301 ccggcgtctt ttcgctgacg cgtcaggccg tgcgtcttgg ctatttgtcg ccaatgcgca
     9361 ttatccatac ctccgagatg gagtccggtc agatctacat ccctttcgtt aactggctgc
     9421 tttatttcgc ggtcgtggtt gttattgtta gctttgagca ctccagcaac ctggcggcgg
     9481 cctatggcat cgccgtgacc ggcacgatgg tgctgacgtc tattctttct acgaccgtgg
     9541 cgcgtaagaa ctggcactgg aacaaatatt ttgtcgcgct gatcctcatc gcattcctgt
     9601 gcgtggatat cccgctgttc tcggctaacc tcgacaaatt gttgtccggc ggttggctgc
     9661 cgctgagcct gggtctgatc atgttcacga tcatgaccac ctggaagagc gagcgtttcc
     9721 gtctgttgcg tcgtatgcat gaacacggta attcgctgga agcgatgatt gcttcactgg
     9781 agaagtcacc gccggttcgg gtgccgggta ctgccgtata catgtcgcgc gcgctcagtg
     9841 tgatcccttt tgctttattg cataacctga agcacaacaa agtgttgcat gagcgcgtaa
     9901 tcttactgac gttgcgtacg gaagatgcgc cttatgtgca taacgttcgc cgggtgcaga
     9961 ttgagcagtt gtctccgaca ttctggcgcg tggtggccag ctacggctgg cgcgaaacgc
    10021 taaacgttga agaggtgttc caccgctgcg gtctggaagg ccttagctgt cggatgatgg
    10081 aaacgtcgtt ctttatgtcg cacgagtcgt tgattgtcgg caaacgcccg tggtatttgc
    10141 gtctgcgcgg caagctgtat ttgttgttgc aacgcaacgc cctgcgcgcg ccggatcagt
    10201 tcgagatccc gcctaaccgc gtgattgagt taggtacgca ggtcgagatt taacctctca
    10261 tcaacatgcc gggggccgca ttggcttacc cggcctggcc aatccgtaga ttcccacaag
    10321 ataatcgcca ttgggcgatt atcttcacct gatttccgct agcgaaacgt ttcgacggcg
    10381 atcacaattc tgttacgtca tgatggtttt atgaacacat ccagggttac actgcggcca
    10441 gcgaaacgtt tcgctagtgg agcagaaaaa tgaagaaagg caccgtactc aactctgaaa
    10501 tctcgtcggt catttcccgt ctggggcata ctgatactct ggtggtctgt gatgcgggtt
    10561 tacccatccc gaatagcact gcgcgtatcg atatggcact aacccagggc gtaccttctt
    10621 ttatgcaggt ggtggatgtc gtgacctggg aaatgcaggt tgaggcggcg attcttgcaa
    10681 cggaaatcaa acaacagaat ccgcagctcc acgaaacgtt gctcactcac cttgagcaac
    10741 tgcagcaaca ccagggaaac accataaaaa ttagttatac gacacacgaa caattcaaaa
    10801 aattgactgc agacagtcag gcagtgattc gcagcgggga gtgttccccg tatgcgaacg
    10861 tcattatttg cgctggcgtc actttctgag gccgctatgg acgcattact gcaactcaaa
    10921 gggatcgata aagcgttccc cggcgtgaag gctctctccg gcgccgcgtt aaacgtttat
    10981 cctggccgcg ttatggcgct ggtgggggaa aacggcgccg gaaaatccac catgatgaaa
    11041 gtattaaccg gcatctatac gcgagatgcg ggatcgttgt tatggctggg taaagagacc
    11101 acctttaatg ggcctaaatc gtctcaggaa gccgggatcg gcattattca tcaggaactg
    11161 aacctgattc cgcagttgac cattgcggaa aacatcttcc tgggccgtga gtttgtgaat
    11221 cgctttggta aaatcgactg gaaaaagatg tatgccgaag ccgaccacct cttagccaaa
    11281 ctcaatctgc gctttaagag cgataagctg gtgggcgaac tctctatcgg cgatcagcaa
    11341 atggtggaaa tcgccaaagt gctgagcttc gaatccaaag tcatcattat ggatgaaccg
    11401 accgatgcgc tgaccgacac tgaaaccgac tctctgttcc gcgttatccg cgaattaaaa
    11461 tcgcaggggc gcggcattgt ctatatctct caccgtatga aagagatttt cgaaatttgc
    11521 gatgacgtga cggtcttccg cgatgggcaa tttatcgccg agcgtgaagt ggccacgttg
    11581 accgaagatt ctcttatcga aatgatggtg ggacgtaagc tggaagatca gtacccgcat
    11641 ctggataacg cgccgggtga gattcgcctg aaggtcgata atctgtgcgg accgggcgtg
    11701 aacgatgtct cttttgtgct gcgaaaaggc gagattcttg gcatctccgg cctgatgggc
    11761 accggtcgca ctgagctgat gaaagtattg tacggcgcga tgccgcgaac cagcggttac
    11821 gtgacgctcg agggacacga agtggtgacg cgttctccgc aggacgggct ggccaatggc
    11881 atcgtttata tctctgaaga ccgtaagcgc gatggactgg tgctcggcat gtcagttaaa
    11941 gagaatatgt cgctgactgc gctggattat ttcagtcgcg ctggcggaag cctgaaacac
    12001 aaagatgagc agcaggcggt gggggatttt atccgtctgt tcaacgtcaa gacgccgtca
    12061 atggaacagg cgataggcct gctttctggc ggtaatcagc aaaaagtggc gattgcccgc
    12121 gggttgatga cgcgcccgaa agtgctcatt ctcgacgagc cgacccgcgg cgtggacgtc
    12181 ggcgccaaga aagagattta ccagcttatc aaccagttta aggccgacgg cctgagcatc
    12241 attctggtct catctgagat gccagaagta ttaggcatga gcgatcgcat catcgtcatg
    12301 catgaagggc atctcagcgg tgaatttact cgcgagcagg ccacccagga agtgttaatg
    12361 gctgccgcag tgggcaagct taatcgcgtg aatcaggagt aaaaaagatg acaacccagg
    12421 ctgtttctgg tcgccgttat ttcactaaag cgtggcttct tgagcagaag tcgctcattg
    12481 ccctgctggt gttgatcgcg attgtttcga cgttgagccc caactttttt accgttaata
    12541 atctgttcaa tattcttcaa cagacctccg tcaacgccat tatggcggtg gggatgacgt
    12601 tggtgattct gacatcgggg atcgatctgt ccgtcggttc cctgctggca ctcaccggtg
    12661 cggttgccgc ttcaatcgtc ggcgttgaag tgaatgcgct ggtcgcggtt gccgccgcgc
    12721 tggcgctggg cgctgcgatt ggcgccgtca ctggcgttat cgtcgcgaag ggccgcgtac
    12781 aggcgtttat cgctacgctg gtgatgatgc tgctactgcg tggcgtgacg atggtttaca
    12841 ccgacggtag cccggtcaac accggcttta ccgataacgc cgatctgttt ggctggttcg
    12901 gtatcggtcg tccgctgggc gttcctacgc cggtctggat catggctatc gtctttatcg
    12961 ccgcctggta tatgctgcat cacacccgtc tgggacgcta tatctacgcg ctgggcggta
    13021 acgaagcggc gacgcgtctg tctggcatta gcgtgagcaa agtgaaaatt atcgtctatt
    13081 cactttgcgg cctgacagca tcgctggcgg gcatcattga agtggcgcgc ctctcttccg
    13141 cgcagccgac ggcgggtacc ggctatgagc tggatgctat tgccgccgtg gtgctgggcg
    13201 gcaccagcct tgcaggtggt aaagggcgca ttgttgggac attgatcggc gcattgattc
    13261 tcggcttcct taataatggt ttgaatttgt taggtgtttc ctcctattac cagatgatcg
    13321 tcaaagcggt ggtgattttg ctggcggtac tggtagacaa caaaaagcag taacaacgac
    13381 tacaggacat ctgaaatatg aacatgaaaa aactggctac cctggtatct gctgttgcgc
    13441 tgagcgccac cgtgagcgcg aatgcaatgg cgaaagacac cattgcgctg gtgatctcta
    13501 ccctcaataa tcccttcttc gtgtcgttaa aagacggggc gcaaaaagag gcggataaac
    13561 tgggttataa cctggtggtg ctggactccc agaacaaccc tgccaaagag ctggcgaacg
    13621 tgcaggattt aaccgttcgc gggaccaaaa ttttgctgat caacccgact gactccgatg
    13681 cggtgggtaa cgcggtgaag atggcgaacc aggcgaagat tccggttatc acgcttgacc
    13741 gccaggcaac caaaggcgat gtcgtcagcc atatcgcgtc tgataacgtg ctgggcggta
    13801 agatcgctgg cgactatatc gcgaaaaaag ctggcgaagg cgccaaagtg attgagctgc
    13861 aaggcattgc cggaacatct gcggcgcgtg agcgtggcga aggtttccag caggcggtag
    13921 ccgcccacaa atttaatgtc ctggccagcc agcctgccga tttcgaccgt actaaaggtc
    13981 tgaacgtcat gcagaacctg ctgaccgcgc atccggatgt tcaggctgtc ttcgcccaga
    14041 acgatgaaat ggcgctgggc gcactgcgcg cgctgcaaac tgccggtaaa gcagatgtga
    14101 tggtggttgg atttgacggt acgccggatg gcgaaaaggc cgtaaaagat ggcaaactgg
    14161 cagcgactat cgctcagtta ccggatcaaa tcggcgccaa aggcgttgaa gtagcggata
    14221 aggtgctgaa aggcgaaaaa gttcaggcca aatatccggt tgacctgaaa ctggtcatca
    14281 agcagtaata aacgacacgg gtcaactatg gcctgatggc gacagaaata cgcgagcctc
    14341 cgctgaggtg aacgtaaaaa aagaaaagca gggcacgcgc caccctaacc ggtggcgcac
    14401 tttgacgtgg aaccccgaat atgaaaaccg caggtaatct catcgtcctt ggcagcatta
    14461 atgccgatca tatccttaat cttgagtcct tccctacccc gggtgaaacg gtaaccggta
    14521 gccattatca ggtcgcgttt ggcgggaaag gcgcgaatca ggcggttgct gcgggacgta
    14581 gcggggcaaa tattgcgttt atcgcctgca cgggcgatga cgatattggc gacagtattc
    14641 gtaaacaatt agtcagcgat cgtattgata tcgcgccagt tagcgtcatt aaaggcgagt
    14701 ctaccggggt agcgctgatt ttcgttaatg gcgaaggcga gaacgtcatc ggtattcatg
    14761 ccggagcgaa tgccgcgtta tcgccggcgt tggttgatgc gcaacgtgaa cgtatcgcgc
    14821 aggcggatgc gttactgatg cagctggaat cgccgctgga aagcgtactg gcggcggcga
    14881 aaatcgccca tcaacatcat actactgttg cgcttaaccc ggcacctgcc cgtgagttac
    14941 cggatgaact gctggcgctg gtggacatca tcacgccaaa tgaaacggaa gctgaaaagc
    15001 tgacgggcgt gcgtgtggaa aatgacgacg atgtcgcgaa agctgcgcag gttttacatg
    15061 ataaaggcat tcgaaccgta ttaattacct taggaagccg tggcgtctgg gccagcgtaa
    15121 acggcgaggg tcgccgcgtt cctggattta gcgttgaggc tgtcgatacc attgccgccg
    15181 gagatacgtt taacggcgcc tttatcaccg cgatactgga ggagacgccg ttgccggaag
    15241 cgattcgctt tgcccatgcc gccgccgcga ttgccgtaac gcgtaaaggc gcgcaacctt
    15301 ccgttccgtg gcgcgaagag atagaagcgt ttttacatca gcaggggtaa cgcttggcta
    15361 ctatgaaaga tgttgcccgc ctggcgggag tctctacatc gacggtctct cacgttatta
    15421 acaaagatcg ctttgtgagt gagacgatta ctgaaaaagt tgaagcggcg attaaatcac
    15481 ttaactatgc gccttccgcg ctggcgcgaa gcctcaagtt aaaccagacc cgcacgattg
    15541 gtatgctgat taccgccagt accaaccctt tttattccga actggtgcgc ggcgttgagc
    15601 gaagctgttt tgagcgcggt tatagtctgg tgctgtgtaa taccgaaggc gatgagcaac
    15661 ggatgaaccg caacctagag acgctgatgc aaaaacgggt agacggttta ctgctgctgt
    15721 gtactgaaac gcatcagcct tctcgtgaaa tcatggaacg ttatccgtct attcctaccg
    15781 tcatgatgga ctggtcgccg tttgatggtg agggcgatag cgatctcatt caggataatt
    15841 cgttgttagg cggcgatctt gcgacccaac accttatcga taaaggattt acccgaatag
    15901 cctgtattac cggcccgctg gacaaaacgc ctgcgcgttt gcggctggaa gggtatcggg
    15961 cggcgatgaa acgcgcaggg ctggctattc cgcaaggcta tgagatcacc ggcgattttg
    16021 aatttggcgg cggctttgac gccatgcagg cgttactcgc ccatcaacag cgaccgcaag
    16081 cggtttttac cggaaacgat gcgatggctg tcggcgccta tcaggcgcta tatcaggcgg
    16141 ggcttcgtat cccgcaagat atggcagtca ttggctatga tgatattgag ctagcgcgct
    16201 atatgacgcc gccgctgacg actatccatc agccgaaaga tgaattgggc gagcttgcta
    16261 ttgatgtgtt gattcatcgg atggcgcagc ccgccttgca acaacagcga cttcagctta
    16321 ctccggtttt gacggtgcgt gggtcggttt agatttatgc cgttctttaa tcagattgtt
    16381 gccgtctttg gctcttagca gcataaacat cagcgcggac acgatagtga tcgcccccat
    16441 cgtgataaag gtatagtgga actgttccac ggtactggtg cccgcaaaac cttcataaat
    16501 acgtaacacc gccgcgctga tcgccacgcc taaactgata gacaattgct gcgtaactgc
    16561 cagaacgctg ttgccgctgc tggcgttatc gtccgtcaga tccgcaagag taatcgtatt
    16621 cattgccgta aattgagtgg acatcgccat tccaagaatg aatagcggca gtacgagcat
    16681 ccagatcggc atagcgggag attgaaacga aaactgggca atcatcagac cgataaatac
    16741 cgtaatgccg accagcgtct tcctgtatcc caaacgtcgt aaaacctgcg ttacggtcga
    16801 tttcgcgata atagaaccca aagccgtcgg cgccatcatg cagccggcga tcagagccgg
    16861 gtagccaaaa ccaacctgta gcattaacgg catcaaaaaa ggtacgcagc ctgtccccag
    16921 acgcgtggcg aggttgccgg caatgccaac ggaaaatgtg cgtgtcttaa acagcgatag
    16981 tgatattaac ggtgtcggat gacggcgggc gtggcggata taggccaata gtagaacgat
    17041 actgcaaaaa ataatggcgg atgcgatcca tgtcgccaca atcttttcgc caaacagttc
    17101 cattccgctg gaaaataaaa ccagacttaa cccaaaaaga aagaagccgg tcatgtcaaa
    17161 cttgcgacgc ggcgtggtga agttgggcat atatttgcgg gcatacagaa tgcctgcaac
    17221 cccaatggga atattaatca ggaagatcca gtgccagctt gcctaggtca ccagtacgcc
    17281 gcctaatacc ggccccagaa tcggacctac cagccccggc atagtgacaa agttaagaac
    17341 gggcagcagc tcactacgcg gataggctcg caataacgcc agtcgcgcca ctggcatcat
    17401 catcgctccg ccgacgcctt gtacgacgcg aaaaataacc aattcagata gtgaactgga
    17461 gagcgcgcag gccagcgagc ctaacgtaaa cagacttacg gcaaccataa agacgcgacg
    17521 cgtaccgaag cggtcagcca gccagccgct taccggaatt aacatggcta ctgtcagggt
    17581 ataactgata atagcggact gcatggcgag tggtgaacag ttaagactat gcgcaatagc
    17641 cggtaaagcg gtattcaaaa tggtggcgtc tagcgcctgc ataaagaagg ccatcgccgc
    17701 gatccacggc aggccagcca tactgcgcgc ttttttgctg gtcattcaat atcctgttaa
    17761 ttatctggtc tctcattggg cgctattaac aacgcctgac aggcctggaa agcgcgttcg
    17821 ccgtcgccat cagcgatggc atcaacaatg gcctggtgca aatccagctt taccacctcg
    17881 ttataggtga ttgaggtaaa gtaagtgtga taaaccgaat gaaatagcgt agcaaaagag
    17941 attagaaagg gattggcgct catttcgtag atatgctcgt gccacgccat atccacttca
    18001 atccagcgtt cacgcttaaa atgctttttc agcgcgacca tctcttccat taaggcatta
    18061 agccgcgctt tctgctccgg tgtgccaaga gtcgccgcca gcaggcaagc ttgcggctcc
    18121 aggctaatac gcatcaccag aaaatgatct accacctgat gaaaattttc ttccgtcatc
    18181 caccaggtca gcagctcttg atccagaaag ttccagtttc cctgcggcat cacccgcgta
    18241 ccaatgcgcg gacggggtag caccatacct ttagccgtca acgttttcac cgcttcgcga
    18301 actgccgttc gacttacgcc gtactgctcg cccagttcta tttcgccggg aagaatcgta
    18361 ccgggggcgt agtcaccctt taatatccgc tgcgccagct tttcagccag aacataggat
    18421 agatttttct gtgcggctaa ttgttgtgcg cttaaaggca tgaatgttct tcctttctct
    18481 ttcgtttggt tattagtatg ccacctggaa gtgtgattgc agttgcaata acggcaattt
    18541 gcttatttta tggcacgtta agcccgctgt tgatgaaaaa agag
//
LOCUS       DAJVKX010000084        18456 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000084 DAJVKX010000000
VERSION     DAJVKX010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18456
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.084"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            334..1923
                     /gene="purH"
                     /locus_tag="OPY25_002994"
     CDS             334..1923
                     /gene="purH"
                     /locus_tag="OPY25_002994"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCS0928555.1"
                     /translation="MQQRRPVRRALLSVSDKAGIIEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEQHHIAPIDMVV
                     VNLYPFAETVAREGCSLADAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DANEGSLTLDTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKQDMRYGENSHQQAAFYIEENVKEASVATAQQIQGKALSYNNIADTDAALECVK
                     EFNEPACVIVKHANPCGVAVSTSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVLIAPSASEEALKITSAKQNVRVLTCGQWASRVPGLDFKRVNGGLLVQDRD
                     LGMVSEAELRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYAKENMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSAMASDAFFPFRDGIDAAAAVGVSCVIQPGGSIRDDEV
                     IAAADEHGIAMIFTDMRHFRH"
     gene            1939..3228
                     /gene="purD"
                     /locus_tag="OPY25_002995"
     CDS             1939..3228
                     /gene="purD"
                     /locus_tag="OPY25_002995"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCS0928556.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVDTVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLSFAQNEKIDLTIVGPEAPLVIGVVDAFRAAGLKIFGPTEGAAQLE
                     GSKAFTKDFLARHQIPTAEYQNFTEIEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GNGDTGPNTGGMGAYSPAPVVTDEVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVDLCLAACDGKLDEKTSEWDERASLGV
                     VIAAGGYPGSYSTGDEIHGLPLEEVADGKVFHAGTKLADDDRVLTSGGRVLCATALGH
                     TVAEAQKRAYALMTDIRWDGSFSRNDIGWRAIEREQN"
     gene            complement(3225..4550)
                     /gene="zraR"
                     /locus_tag="OPY25_002996"
     CDS             complement(3225..4550)
                     /gene="zraR"
                     /locus_tag="OPY25_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HCS0928557.1"
                     /translation="MIRGKIDILVVDDDVSHCTILQALLRGWGYNVALAYSGHDALAQ
                     VREKVFDLVLCDVRMAEMDGIATLKEIKALNPAIPILIMTAFSSVETAVEALKAGALD
                     YLIKPLDFDRLQETLEKALAHTRETGAELPSASAAQFGMIGSSPAMQHLLNEIAMVAP
                     SDATVLIHGDSGTGKELVARALHACSARSDKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPLMQVRLLRAIQEREVQRVGSNQTISVDVW
                     LIAATHRDLAEEVSAGRFRQDLYYRLNVVAIEMPSLRQRREDIPLLADHFLRRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAIERAVVLLTGEYISERELPLAIAATPIK
                     AENSAEIQPLVDVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(4556..5953)
                     /gene="zraS"
                     /locus_tag="OPY25_002997"
     CDS             complement(4556..5953)
                     /gene="zraS"
                     /locus_tag="OPY25_002997"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HCS0928558.1"
                     /translation="MSFIRLHKDAAAMWLSRLLPAAIFILVGLFSIMVIRDYGRESAA
                     ARQTLLEKGNVLIRALESGTRVGMGMRMHHAQQQTLLEEMAGQPGVLWFAVTDAQGVI
                     ITHSNPGMVGKSLYSPSEMHQLNPGPQECWRRVDVAANGETVPALEIYRQFQPLFGMR
                     GHGMRGHGMARSANDDEPAKQTIFIAFDASELAATQAREWRNTLIVLSALAAVLLATL
                     LAFFWYQRYQRSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERT
                     PAGGESHELAQVMAKEADRLNRVVSELLELVKPAHLTLQAVNLNDIITHSLNLVSQDA
                     QSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTITVEAKESGTDRV
                     IITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKG
                     AVFTIWLPVIARQQD"
     gene            6207..6662
                     /gene="zraP"
                     /locus_tag="OPY25_002998"
     CDS             6207..6662
                     /gene="zraP"
                     /locus_tag="OPY25_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HCS0928559.1"
                     /translation="MKRNNKSAIALIALSLLALSSGAAFAGHHWGNNDGMWQQGGSPL
                     TTEQQATAQKIYDDYYTQTSALRQQLISKRYEYNALLTASSPDTAKINAVAKEMESLG
                     QKLDEQRVKRDVAMAQAGIPRGAGMGYGGCGGYGGGYHRGGGHMGMGNW"
     gene            complement(6704..7396)
                     /locus_tag="OPY25_002999"
     CDS             complement(6704..7396)
                     /locus_tag="OPY25_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HCS0928560.1"
                     /translation="MNSFIEGACQPLLSVWRRAFLFSGALLLTACSHNASPPPFTASG
                     FAGDHGAVRIWRKDTNDEVHLLSVFSPWHSGSTTTSEYRWQGDTLSLIELNIYSKPPE
                     HIRARFDAHGELSFMQREVGGQKQQLSNDQIALYRYRAEQIRQTSDALRLGRVILRQG
                     RWHADHTVTTCEGETLKPDLDSWAISHIERRQNHSSVEVSVAWLEAPEGSQLLLVANS
                     DFCHWQPQAKTF"
     gene            complement(7408..7680)
                     /gene="hupA"
                     /locus_tag="OPY25_003000"
     CDS             complement(7408..7680)
                     /gene="hupA"
                     /locus_tag="OPY25_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HCS0928561.1"
                     /translation="MNKTQLIDVIADKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            complement(7867..8457)
                     /locus_tag="OPY25_003001"
     CDS             complement(7867..8457)
                     /locus_tag="OPY25_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HCS0928562.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCKQTEFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPAADDYDLYGVYPAIDACVALSE
                     LMHSRLSGETLEHAIEVSKTSITTVAMLEMTQAGREMTDEELKTNPAVEQEWDIQWEI
                     FRLLADCEERDIELIKGLRADLREAGESNIGINFQQ"
     gene            complement(8499..9170)
                     /gene="nfi"
                     /locus_tag="OPY25_003002"
     CDS             complement(8499..9170)
                     /gene="nfi"
                     /locus_tag="OPY25_003002"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HCS0928563.1"
                     /translation="MDLASLRAQQIELASSVCREDRLDKDPPAFIGGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEQLSQKPDLLFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSAEPGALSPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSTDSALAWVQRCMKGYRLPEPTRWADAVASGRPAFVRW
                     QEIQR"
     gene            complement(9180..10244)
                     /gene="hemE"
                     /locus_tag="OPY25_003003"
     CDS             complement(9180..10244)
                     /gene="hemE"
                     /locus_tag="OPY25_003003"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HCS0928564.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKTTRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTIPDAMGLGLYFEAGEGPRFTAP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHLLLDKLAKSVTLYLNAQIKAGAQSVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGHKVALQGNMDPSMLYAPPARIEDEVATILAGFGQGEGHVFNLGHGIHQDVP
                     PEHAGAFVEAVHRLSAQYHN"
     gene            complement(10285..11058)
                     /gene="nudC"
                     /locus_tag="OPY25_003004"
     CDS             complement(10285..11058)
                     /gene="nudC"
                     /locus_tag="OPY25_003004"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HCS0928565.1"
                     /translation="MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRAL
                     RIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCG
                     HPMHPSKTEWAMLCSHCRDRYYPQIAPCIIVAIRREDSILLARHVRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD"
     gene            11151..11639
                     /gene="rsd"
                     /locus_tag="OPY25_003005"
     CDS             11151..11639
                     /gene="rsd"
                     /locus_tag="OPY25_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HCS0928566.1"
                     /translation="MLNQLENLMERVGGSNKLVDRWLDVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLLHAAKIWPLLEDNTQR
                     IMDYYDTSLETAIDHDNCLEFQQALSDIGEALEARFVLEDKLIMLVFDAMHDGARVKR
                     PA"
     regulatory      11754..11917
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            12003..13898
                     /gene="thiC"
                     /locus_tag="OPY25_003006"
     CDS             12003..13898
                     /gene="thiC"
                     /locus_tag="OPY25_003006"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HCS0928567.1"
                     /translation="MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRV
                     PMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWID
                     ARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARQGIVTP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICSAYDVSLSL
                     GDGLRPGSIQDANDEAQFSELHTLGELTNIAWEYDVQVMIEGPGHVPMHMIQRNMTEE
                     LESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEI
                     YLKREEA"
     gene            13898..14533
                     /gene="thiE"
                     /locus_tag="OPY25_003007"
     CDS             13898..14533
                     /gene="thiE"
                     /locus_tag="OPY25_003007"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HCS0928568.1"
                     /translation="MYQPDFPTVPFRLGLYPVVDSVAWIERLLEAGVRTIQLRIKDKR
                     DEEVEADVIAAIALGRCYDARLFINDYWRLAIKHNAYGVHLGQEDLETTDLKAIQAAG
                     LRLGVSTHDDMEIDIALAAKPSYIALGHVFPTQTKQMPSAPQGLAQLARHIERLADYP
                     TVAIGGISLERAPAVLATGVGSIAVVSAITQAADWRAATAQLLAIAGVGDE"
     gene            14526..15284
                     /locus_tag="OPY25_003008"
     CDS             14526..15284
                     /locus_tag="OPY25_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesA/MoeB/ThiF family protein"
                     /protein_id="HCS0928569.1"
                     /translation="MNDRDFMRYSRQILLGDIAIEGQQKLLNSHVLIVGLGGLGSPAA
                     LYLAGAGIGTLTLADDDDVHLSNLQRQILFTTDDIARSKSQVAQQHLTRLNPDIELVS
                     LQQRLKGDALRHAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQVMV
                     LTPPWEQGCYRCLWPDDVEPERNCRTAGIVGPVVGVMGTLQALEAIKLLSGIETPSGE
                     LRLFDGKTSQWRSLALRRASGCPVCGGRHANSIQ"
     gene            15265..15465
                     /gene="thiS"
                     /locus_tag="OPY25_003009"
     CDS             15265..15465
                     /gene="thiS"
                     /locus_tag="OPY25_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HCS0928570.1"
                     /translation="MQIQFNDEPMQCAEGQTVSSLLATLNQLQPGAALALNQQILPRE
                     QWRQHIVQEGDQILLFQVIAGG"
     gene            15467..16237
                     /gene="thiG"
                     /locus_tag="OPY25_003010"
     CDS             15467..16237
                     /gene="thiG"
                     /locus_tag="OPY25_003010"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HCS0928571.1"
                     /translation="MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKR
                     VDLRQHNDAILAPLIEAGVTLLPNTSGAKTAEEAIFAAQLALEALGTHWLKLEIHPDA
                     RWLLPDPIETLKAAEALVKQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETKAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVMMAT
                     AFRLAVEAGLLARQAVPGNRSTYASATSPLTGFLEALA"
     gene            16234..17367
                     /gene="thiH"
                     /locus_tag="OPY25_003011"
     CDS             16234..17367
                     /gene="thiH"
                     /locus_tag="OPY25_003011"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HCS0928572.1"
                     /translation="MKAFTDRWRQLEWDDIRLRINGKTAADVERALNASRLNREDMMA
                     LLSPAAADYLEPMAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEVDIQRECDAIRKLGFEHLLLVTGEHQAKVGMDYFRRHLPTIRRQFSSLQMEVQ
                     PLSQENYAELKTLGIDGVMVYQETYHEAIYAQHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDNWRVDCYMVAEHLLWMQKHYWQSRYSVSFPRLRPCTGGVEPASVMD
                     EKQLVQTICAFRLLAPEIELSLSTRESPWFRDHVIPLAINNVSAFSKTQPGGYADDHP
                     ELEQFSPHDDRRPEVVASALSAQGLQPVWKDWDSWLGRASQMR"
     gene            complement(17448..17663)
                     /locus_tag="OPY25_003012"
     CDS             complement(17448..17663)
                     /locus_tag="OPY25_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928573.1"
                     /translation="MDKNDQQTRLEEGPPAKLQSGTLPENFKFTAISIIQWPAPGRQL
                     LMKGRRLGKNEEGIICPGQLPLLTMTK"
     gene            18117..>18456
                     /locus_tag="OPY25_003013"
     CDS             18117..>18456
                     /locus_tag="OPY25_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0928574.1"
                     /translation="MLQKKPNPMVKNFNFEYCGFSTFITPVDGVGGILAKWLSNKHNV
                     SVPTPYTFGQDPIPGINLYRNTKAKFVMANGGNSLPCAISKYNAKTGQFIHITSDNDF
                     SPIIRETRVMK"
BASE COUNT         4254 a         5226 c         4943 g         4033 t
ORIGIN      
        1 cattataggg agttatctgc tgaccgcaat agaaaaattg cagaaaaatg actgtttgct
       61 gcattcccca gcaaaaccct tggttatacc catttacgca cagacttatc cacaaaatgc
      121 gcgttcattt cctcgatctt ctcactctgc aaacgatctt tcagggataa aagcggggcc
      181 agaatttaaa gagaaaaatt cgcgagcgtt gcgcaaacgt tttcgttaca atgtcgccgc
      241 aaaatgagaa tgccccataa ggagcgttag ctgagttttt cacgaaaaat tcagctaacg
      301 ctctctataa tcgtcaaatc caggggattt accatgcaac aacgtcgtcc agtccgccgc
      361 gctttgctca gtgtttctga caaggccggt atcatcgaat tcgcccaggc actttccgca
      421 cgcggtgtgg agctgctgtc tacggggggc accgcccgcc tgttagcaga aaaaggcctg
      481 ccggtgaccg aagtttccga ttacaccggt ttcccggaaa tgatggatgg acgcgtaaag
      541 accctgcatc caaaagtaca cggtggcatc ctcggtcgtc gcggtcagga cgatgccatt
      601 atggaacagc accacatcgc ccctatcgat atggttgtcg ttaacctata tccgttcgcc
      661 gaaaccgtgg cacgcgaagg ctgctcgctg gcagatgcag tagagaacat tgatatcggc
      721 ggcccgacca tggtgcgctc tgctgctaag aaccataaag acgtcgccat cgtggtgaag
      781 agcagcgact acgacgccat tattaaagag atggatgcta acgaaggttc tctgaccctc
      841 gacacccgtt tcgatctcgc gattaaagcc ttcgaacaca ccgccgccta cgacagcatg
      901 atcgccaact acttcggcag catggttccg gcctaccacg gtgaaagcaa agaagccgcc
      961 ggtcgcttcc cgcgtacgct gaacctgaac ttcattaaga agcaggatat gcgctacggc
     1021 gagaacagcc accagcaggc tgccttctat atagaagaga atgtgaaaga agcatccgtt
     1081 gccaccgcac agcagattca gggcaaagcg ctctcttata acaatatcgc cgataccgat
     1141 gcggcgctgg aatgcgtgaa agagttcaac gagccagcct gcgtgatcgt caagcacgcc
     1201 aacccgtgcg gcgtggcggt aagtacctcg attctcgatg cttatgaccg tgcgtataaa
     1261 acagacccga cctccgcgtt cggcggcatt atcgccttca accgcgagct ggatgccgaa
     1321 accgcgcagg ccatcatctc ccgtcagttc gtggaagtgc tcatcgcccc atccgcaagc
     1381 gaagaagcgc tgaaaatcac ctcagccaag cagaacgtcc gtgttctgac ctgcggccaa
     1441 tgggcaagcc gcgttccggg cctggatttc aaacgcgtta acggcggtct gctggttcag
     1501 gacagggatc tgggtatggt gagcgaagct gaactgcgcg tggtgtccaa acgccagccg
     1561 accgagcagg aactgcgcga tgcgctgttc tgctggaagg tagccaagtt cgtgaaatcc
     1621 aacgccattg tgtatgccaa agagaacatg actatcggca taggcgcagg ccagatgagc
     1681 cgcgtgtact ccgcgaaaat cgctggcatt aaagcggctg acgaaggtct ggaagtgaaa
     1741 ggctctgcta tggcttccga cgcgttcttc ccgttccgtg atggcattga tgccgctgcc
     1801 gctgtcggcg tgagctgcgt tatccagcct ggcggttcta tccgtgatga tgaagtcatt
     1861 gccgccgccg acgaacacgg cattgcgatg atcttcaccg acatgcgcca cttccgccat
     1921 taattcaggg agcagacgat gaaagtttta gtcattggta acggcgggcg cgaacatgcg
     1981 ctggcctgga aagccgcaca gtcgccgctg gttgataccg tttttgtcgc accgggtaac
     2041 gccggtaccg cgctggagcc cgcgttgcag aacgtggcta tcggcgtcac cgatattccg
     2101 gcgctgctga gctttgccca gaacgagaag attgatctga ccatcgtcgg tccggaagcg
     2161 ccgctggtga tcggcgtggt cgatgcgttc cgcgcggcgg gtctgaagat ctttggccca
     2221 accgaaggag ccgcgcaact ggaaggctcc aaagcgttca ccaaagattt cctcgcccgt
     2281 catcagattc cgacggcgga ataccagaat ttcaccgaga ttgagcctgc cttggcttat
     2341 ctgcgtgaga agggcgcgcc gatcgtcatc aaggccgatg gtctggctgc gggcaaaggc
     2401 gtcatcgtgg cgatgacgct ggaagaagcc gaagccgccg ttcatgacat gctggcaggc
     2461 aacgcctttg gcgacgcggg ccaccgtatc gtgattgaag agttcctcga cggcgaagaa
     2521 gcgagcttta tcgtgatggt cgacggcgag cacgtgctgc cgatggccac cagccaggat
     2581 cacaaacgcg taggcaacgg cgataccggc ccgaatactg gcggcatggg tgcttactcc
     2641 ccggcgccgg tggtgactga tgaagtgcac cagcgcacca tggaacgcat catctggcca
     2701 accgtgaaag gcatggcagc agaaggtaac acgtacaccg gcttcctgta tgcgggtctg
     2761 atgatcgaca agcagggcaa cccgaaagtt atcgagttca actgccgctt cggcgatccg
     2821 gaaacccagc cgatcatgct gcgcatgaaa tcggatctgg tggatctttg cctggccgcc
     2881 tgtgacggca agctggatga gaaaacctcc gagtgggacg aacgcgcttc attaggcgtg
     2941 gtgatcgccg cgggcggtta tccgggcagc tacagcaccg gcgacgagat ccacggtctg
     3001 ccgctggaag aagtggctga cggtaaggtt ttccacgcgg gcaccaaact cgccgatgac
     3061 gaccgcgtgt tgaccagcgg cggtcgcgta ctgtgcgcca ccgcgctggg ccacaccgtg
     3121 gccgaagcgc agaaacgcgc ttacgccctg atgaccgaca tccgctggga cggcagcttc
     3181 agccgtaacg acattggctg gcgcgccatt gagcgtgagc aaaactaacg gctgagttta
     3241 gccagcagcg ttttgcgcgt aatgcccaat tgacgggcgg cttccgtttt gttgccgccc
     3301 gttttttcca gcgccgccag aatcacctct ttctccacat cgaccaacgg ttggatttcg
     3361 gcgctgtttt ccgcttttat cggcgtcgcg gcaatagcga gaggcaattc gcgttcagaa
     3421 atgtattctc ccgtcagcaa caccaccgct cgttcgatag cgttttccag ctcacggata
     3481 ttacccggcc agtcgtagtg gatcagcaga tccatcgcct gcggcgtaaa ccccttcacc
     3541 gcttttcggt tacgttcggc aaaacgccgc agaaaatggt ctgccagtag cggaatatct
     3601 tcccgacgct ggcgcaaaga aggcatttca atcgccacca cattcaggcg gtaatagaga
     3661 tcctggcgaa agcgaccggc actcacctct tccgccaggt cgcggtgggt agcggcaatt
     3721 aaccaaacat ccacagatat cgtctggtta cttcccacgc gttgcacttc gcgctcctga
     3781 atcgcccgca gcaaacgtac ctgcattaac ggcgagatat cgccgatttc atcaagaaac
     3841 aatgtcccgc cgtcagcttc gacaaagcgt ccctcccgac gtttatccgc gccggtaaac
     3901 gcgccttttt cgtgtccgaa cagctcagac tccagcagcg attcattaag cgccgcgcag
     3961 ttgagcgtga ccagcggttt atcgctcctg gcgctacagg cgtgcagcgc ccgcgccacc
     4021 agctctttac ccgtgccgga gtctccgtga atcaataccg tggcgtctga tggtgcgacc
     4081 atcgcgattt cattcaataa atgttgcatc gccgggctgc tgccaatcat gccaaattgc
     4141 gcagccgacg ccgatggcaa ttcagcgccc gtttcccgcg tatgcgccaa cgccttttcc
     4201 agcgtctcct gcagacggtc aaaatccagc ggtttaatta aatagtcgag cgcgccggct
     4261 ttcaacgcct ctaccgccgt ttccacgctg gagaatgccg tcataatcaa aatcggaatg
     4321 gcggggttga gcgctttaat ctccttcagc gtggcgatac cgtccatctc cgccatacgc
     4381 acatcgcaca gtaccagatc aaagactttc tcacgcacct gagccaacgc atcatgccca
     4441 ctgtaggcca gagcgacgtt atagccccag ccccgaagca gcgcctgtaa aatcgtgcag
     4501 tggcttacat catcatccac aaccagaata tcgatttttc cgcgtatcac ccttgttaat
     4561 cctgttgtct cgctatcact ggcaaccaga tagtaaagac cgcgccttta ccctcaatac
     4621 ttttcacctt aatcgcgccg ccatgctgtt cgatgatatt ttgcaccacc gccagcccca
     4681 ggcctgtccc gtcagctttg gtcgtaaaat aaggtgtaaa aatcgcctcc agctgatccg
     4741 gggcaatccc tttcccgcta tcggtaacag tgatgataac gcggtcggtc ccactttctt
     4801 ttgcctctac ggtaatcgtt ccctggcggc caatcgcatg aatagcgttc aggtacaaat
     4861 tcaacagcac ctgagtcagc ctgtccgggt cagcctgaat acgcttaagc gtctcattcg
     4921 ccgtgaatct caactgaatc tctctgcttt gggcatcctg actgaccaga ttcagggagt
     4981 gagtaataat atcattgagg ttaaccgcct ggagcgtcag atgcgcgggc tttaccagtt
     5041 cgagcaattc gcttaccacc cggttcaaac ggtcggcctc tttggccatc acctgcgcca
     5101 gttcatgcga ctcgccgccg gcaggcgtgc gctcggcaaa gtatttcgcc agccctttga
     5161 tggacgagag cgggttacga atttcgtgcg cgacgcccgc cgccagatgc cccatcgcca
     5221 ccagcttttc tttacgcttc attgcatcaa gcagttctct gtgcgagcgc tgataacgct
     5281 gataccaaaa aaacgccagt aacgttgcca acagcaccgc cgctaacgca gacaaaacaa
     5341 tcagcgtatt acgccactcc cttgcctgag tcgcggccag ctcgctggcg tcaaaggcaa
     5401 taaaaatagt ttgtttcgct ggttcgtcgt cattggcgct acgcgccatg ccgtgccccc
     5461 tcataccgtg acctctcata ccgaaaagcg gctggaactg acggtaaatt tccagcgcag
     5521 gcaccgtctc gccgttagca gcaacgtcga cacgccgcca acactcctgc ggcccggggt
     5581 ttagttgatg catttcagat ggggaataga gcgacttgcc caccatgcca gggttgctat
     5641 gagtgatgat taccccctgt gcatccgtta cagcgaacca caacacgcct ggctgacccg
     5701 ccatctcttc cagcaatgtc tgctgctgcg cgtgatgcat ccgcattccc atacctactc
     5761 gcgtgccgga ctccagagcg cgaatgagta catttccctt ttccagcagc gtctgcctgg
     5821 cggcagcgct ctcacggcca tagtcgcgaa tgaccataat ggaaaatagc cccaccagaa
     5881 tgaagatcgc cgcaggtaac agccgactca accacattgc agcggcatct ttatgtaatc
     5941 gtataaaact cacaggcttc cccggctcgt ttttattttc cttacttaag cagagatcat
     6001 gccattcttc gctccgcata accgcgcgtt gtcgcacacc ctttcggata cggatgggta
     6061 aaaatgactc gccaggcggg tcatgcgagt catttttact cgctttttgc cgcctgaagc
     6121 gggttaactc gctgcccgac aaggaatagt tacctggcac ggaagatgca agagagagga
     6181 taagatgagc aacaggagaa cgcaaaatga aacggaacaa taaatcagct atcgcgctaa
     6241 tcgccctctc tcttttggcc ctgagctccg gcgccgcctt cgccgggcat cactggggca
     6301 acaatgacgg tatgtggcaa cagggaggta gcccgttaac cacggaacag caggcgacgg
     6361 cgcagaagat ttatgatgat tactatacgc agaccagcgc gctgcgccag caactgatat
     6421 ccaaacgtta tgaatacaac gcgctactga ccgccagttc gccggatact gcgaaaatta
     6481 acgcggttgc caaagagatg gagtcattag gccagaagtt agatgagcaa cgcgtgaaac
     6541 gggatgtcgc gatggcgcag gctggcatac cacgcggcgc aggaatgggc tatggcggtt
     6601 gcggcggcta tggcggcggt tatcatcgcg gcggcggtca tatgggtatg ggaaactggt
     6661 aaagcatgtt tgccgaatgg cggcttcgcc attcggtatt ccatcaaaag gttttcgctt
     6721 gcggctgcca gtgacagaaa tctgaattcg ccaccagcaa aagttgcgat ccttccggcg
     6781 cctccagcca tgctacgctc acctctaccg atgagtggtt ctggcggcgc tcaatgtggc
     6841 ttattgccca agaatccaga tccggtttca gcgtttcacc ttcacaggtg gttaccgtat
     6901 ggtcggcgtg ccagcgtccc tggcgtagta tgacccgccc caggcgcaat gcgtcgctgg
     6961 tctgacggat ttgttcggca cgatagcgat acaaggcaat ctgatcgttg gaaagctgct
     7021 gcttctgccc cccgacttca cgctgcataa aactgagttc gccatgagcg tcgaaacgcg
     7081 cgcgaatatg ttctggcggt ttgctgtaaa tattgagttc aataagcgaa agcgtatcac
     7141 cctgccaacg atattcgctg gtcgtcgtgc taccactatg ccacgggcta aaaacagaaa
     7201 gcagatggac ttcatcgttc gtatctttac gccagatacg caccgcgccg tgatcgccgg
     7261 caaagccgct ggcagtaaac ggaggcggtg aagcgttatg actgcaggca gtcagcaaca
     7321 gcgcgccaga aaacagaaac gcgcgacgcc agacggacaa aaggggctga caagcccctt
     7381 cgataaaact gttcacagtt acgcgtctta cttaactgcg tctttcagag ctttaccaga
     7441 aacaaacgcc ggtacgttag cggcggcgat tttgatttct ttaccggtct gtgggttacg
     7501 gccagtgcgc tcagcacggt ggttcacttt gaaggtaccg aaaccaacca gttgtacagc
     7561 atcgccttct ttcagagact cagtaatagc agccagagtg gattccagag cagctttagc
     7621 ctgggttttg gacagttctg ctttgtctgc aattacatca atcagttgag tcttgttcat
     7681 aagttatcct tacaatgtgt ttatcgcttg ctaagcatcg agtgcgacgg aaatgccaga
     7741 aaagcactct cctgcataca cgcaccgata gccacttttt ttcgcctccc aaatgtagac
     7801 cagacggggg gcataaggga agccttatgg cacgacaaat cagacgttaa atcacgtttt
     7861 ctggtgtcat tgctgaaaat ttataccgat attgctctcg ccagcctcgc gcaggtctgc
     7921 cctgagccct tttatcagtt caatatcacg ttcttcgcag tcggctaaaa gtcggaatat
     7981 ttcccactga atatcccatt cctgttcaac ggcagggttc gttttgagct cctcatcggt
     8041 catttcccga ccagcctgag tcatttccaa catcgctacc gtagtaatgg aagtcttact
     8101 aacctcaata gcatgttcca gcgtttcgcc gctaagacga gaatgcatta attcgcttaa
     8161 tgcgacgcag gcatcaatcg ccgggtaaac gccgtacaaa tcatagtcgt cggctgccgg
     8221 aattgcctct tcaaacttct ccagttggct atcgaaattg acctttgcat ctttcaccgt
     8281 cagggtttcc cagatcagat ccagaatgcg acggtagatc tgtccgtcgc cgaattccgt
     8341 ctgcttgcaa aacatggcgt agttcgggta catgcgctcg cacaagcagg ccataaaggt
     8401 aacgtgctgc caactttcca gccgctccag ccgcaaatga atcgggtttt gtaacatgat
     8461 ggaatctcga atcggaaatt agcggcagtt tacctgaatc agcgctgaat ttcttgccaa
     8521 cgaacaaacg ccggacgccc ggaagcgacg gcatccgccc agcgcgtcgg ctccggcagg
     8581 cgataccctt tcatacagcg ctgtacccac gccagcgcgc tgtcagtact gacccggtgc
     8641 cctgtcgcga taaacagcgg attacagcgc gccttgctgc gccataccca cgccagttgc
     8701 tcgcctttat ccattaaggg gctaagtgcg ccaggttcgg cggaaagtgg ttcaaattta
     8761 ccgcatagcc gttttttcgc cacgccgatg gtcggcacgt ccaccaacag tccaaaatga
     8821 ctggcgacgc caagccgacg cggatgcgaa ataccgtgac cgtccacaaa cagcaaatcg
     8881 ggcttttgcg agagctgttc ccacgctgcc agcagcgcag gatattcacg aaaagagaga
     8941 aagccgggga tatacggcat ggtggtggca atacgcgcca ccttgtactc tactagctca
     9001 agcgacggat atttcagcaa taccatcgcc gcccgcgtca cctcgccgcc ctgctcaaaa
     9061 ccgacgtccg ccccgccgat aaacgctggc ggatctttgt ccaggcgatc ttcgcggcaa
     9121 actgatgaag caagttctat ctgttgagcg cgtagcgacg cgagatccat actaactcct
     9181 tagttgtgat actgcgcaga aagtcggtgc actgcctcca caaatgcgcc agcatgttct
     9241 ggcggcacat cctgatggat gccatgtcca aggttaaaga cgtgcccttc tccctgaccg
     9301 aaaccagcaa gtatagtcgc tacctcgtct tcgatccgtg ccggcggcgc atacagcatg
     9361 gacggatcca tattgccctg cagcgccact ttatggccaa cgcgacggcg cgcatcggcg
     9421 atatctgtcg tccagtcgag acccagcgca tcgcagccgg tttccgccat cgcctccagc
     9481 cactgaccgc cacctttagt gaacagcgtt accggcacgc ggcgaccgtc gttttcacgc
     9541 agcaggccat cgacgatttt atgcatgtag tagagggaga actgctggta atcgcggcca
     9601 gtcagcacgc cgccccaggt gtcgaaaatc atcaccgact gcgcgcccgc tttgatttgc
     9661 gcgttgaggt acagcgtgac gcttttcgcc aacttatcca gcagcagatg caacgcctgc
     9721 gggtcagcgt acatcatctt tttaatcacc gtgaaggctt tgctactgcc gccttccacc
     9781 atgtaagtcg ccagcgtcca cgggctgccg gagaagccga tcagcggaac ctcgcctttt
     9841 agttcgcggc gaatcgtgcg taccgcattc atcacgtagc ccagttcatc ctccggatcg
     9901 ggaatgggca gcttatcgac atcggctttg caggtgacag gggccgtaaa gcgcgggcct
     9961 tccccggctt caaaatagag ccccaggccc atcgcgtccg gaatcgtcag gatatccgag
    10021 aaaaggatcg ccgcatcaag cggataacgg cgcagcggct gtaaagtgac ttcgcaggcc
    10081 agttcggcat ttttgcacag cgacataaaa tcgcccgcct gagcgcgagt ggttttgtac
    10141 tccggtagat aacggcccgc ctggcgcatc atccacactg gcgtaacatc aacgggctgg
    10201 cgcagcagcg cacgtagata acgatcgttt ttgagttcgg tcatttttac attcctttag
    10261 cgttgatgcg cccagtgtaa catgtcagtc gtattcagcc cgacacattg ccaccgtatc
    10321 ttcgatcaaa cggcgcgcga cggtgcccgg cggcggcagt agcggcagat cgtcataacg
    10381 gtaccaattt gcttccaaca gttctttcgg gtcgatgaca atctcgccgc tgtcatactc
    10441 tgccataaac gccgtcatca gcgactgtgg gaacggccac ggctgcgagg tcacgtagcg
    10501 cagatttttc accttgatcc cgctttcctc catgacttcg cgcgccacag cctgctccag
    10561 ggtttcgccg acttcaacaa acccggccag taccgtatgc acgccgttgc ggtggcgaac
    10621 gtgccgggca agtagaatag aatcctcacg gcgaatggca acaataatgc agggggcgat
    10681 ttgcgggtag taacgatcgc ggcaatggct gcacagcatc gcccattcgg ttttactcgg
    10741 gtgcataggg tgcccgcaat agccgcaaaa tttatgcgaa cgataaaact ccgccaactg
    10801 tacgccacgt cccgccagtt gaaacagccc ggcatcctga tcgataacct ggcgaaccga
    10861 tcccatatca tgacgtcgat gctgtaacac cagccagacg ggctcgcctt gccattcacc
    10921 tatccggagt gcgcgctgcc ccacaagatc gaaatttgcc gccagcccgt gtggtaattc
    10981 cccatacggc aaccataatt tttgttcatg gctgacgatc caccagccac tctctaattt
    11041 ttcaattata cgatccatag ctattgcact acctttgctt cactggcatg ttgttaacat
    11101 tatttttaca ttcatggcga gcagccttta tctaacttgc ggagacaatc atgctaaacc
    11161 agctggaaaa cctgatggag cgcgttggcg gaagcaacaa actggtcgat cgctggctgg
    11221 atgtacgtaa gcacctgctc gtggcttact acaatctggt tggcattaag cctggcaaag
    11281 aatcgtacat gcggctgaat gaaaaagcgc tggatgattt ttgtcagagc ctggtcgatt
    11341 acctttccgc cgggcacttc agtatttatg aacgtattct ccataaattg gaaggaaacg
    11401 gtcagctttt acatgcggca aaaatttggc cgctgctgga agataatacg cagcgcatta
    11461 tggattatta cgacaccagc ctggaaactg ccatcgatca cgataattgt ctcgaatttc
    11521 aacaagctct gtcagatatc ggcgaagcgc tggaagcccg ctttgtgctg gaagacaagc
    11581 tgattatgct ggtgtttgac gcgatgcacg acggcgccag agtcaaacgt cccgcttgag
    11641 ttctgcgcga gtaacaggta gtttacttca gccccctctt cggaggggcg gttatcttgt
    11701 cggagtgcta attttccaca aaagcgttcg tgatgcgtca aggcggcaag tcggtgaatc
    11761 tccaggagct tacataagta agtgactgga gtgagcggac gaagccaacg aagaggcagc
    11821 gcgaaggatg aagtggaaaa ggctgagacc gttaattcgg gatccgcgga acctgatcag
    11881 gttaatacct gcgaagggaa caagagtaat tctgctttat gctgctgcct ttacgggcgg
    11941 cgcacatcca ttactccatc cgtcgtctga caagccacgt ccttaatttt ttggaatgag
    12001 ctatgtctac aacaacgtta acccgccgcg agcagcgcgc taaagcccag cattttatcg
    12061 atacgctgga agggactgcc tttcccaact cgaaacgcat ctacgtgacc ggttcgcagc
    12121 atgatattcg cgtaccgatg cgcgaaattc aacttagccc tacgctcatc ggcggcagta
    12181 aagacaaccc gcagtttgaa gagaacgaag ccgtaccggt atacgacacc tccggcccct
    12241 atggcgatcc tgaagtggcg attaacgtcc agcagggtct ggcgaaactg cgccagccgt
    12301 ggattgacgc acgtaacgat agcgaagaat tagacgaccg tagctcggct tacaccagag
    12361 aacgtctggc cgacgatggc ctggacgatc tgcgttttac cggcctgctg acgccgaaac
    12421 gcgctaaagc gggcaagcgc gtcacccagt tacactacgc ccgccagggg atcgtcactc
    12481 ccgaaatgga gttcatcgcc atccgtgaaa acatgggccg cgagcgcatt cgcagtgaag
    12541 tgctgcgcca ccagcatccg ggcatgaact ttggcgcgcg cctgccggaa aacattacgc
    12601 cggaattcgt gcgtgatgaa gtcgccgcgg gccgcgcgat tattcccgcc aacatcaacc
    12661 acccggaatc ggagccgatg attatcggcc gcaacttcct ggtcaaagtg aatgccaaca
    12721 tcggtaactc ggcggtcacc tcctccatcg aagaagaggt cgagaagctg gtgtggtcaa
    12781 cccgctgggg cgcggacacg gtgatggacc tctccaccgg tcgctatatt cacgaaaccc
    12841 gcgaatggat cctgcgtaac agcccggtac cgatcggcac cgtcccgatc taccaggcgc
    12901 tggaaaaggt caacgggatc gccgaagatc tcacctggga agcgttccgc gacacgctgc
    12961 tggagcaggc cgaacagggc gtcgactact tcaccatcca cgccggcgtg ctgctgcgct
    13021 acgtgccgat gaccgccaaa cgcctgaccg gtattgtctc gcgcggcggt tcgatcatgg
    13081 caaagtggtg tctctcccat cacaaagaga acttcctgtt cgaacatttc cgcgagattt
    13141 gtgaaatctg ctccgcctac gacgtttccc tgtcgctggg cgacggcctg cgccccggct
    13201 ccattcagga cgccaacgac gaagcgcagt tctccgagct gcatacgctg ggcgagctga
    13261 ccaatatcgc ctgggaatac gacgtgcagg tgatgattga aggcccgggc cacgtgccga
    13321 tgcatatgat tcagcgcaac atgaccgaag agctggagag ctgccacgaa gcgccgttct
    13381 acaccttagg gccgttgacc accgatatcg cgccgggcta tgaccacttc acctctggca
    13441 ttggcgcggc gatgatcggc tggtttggct gcgcgatgct gtgttacgtg acgccgaaag
    13501 agcatctcgg cctgccgaac aaagaagatg tgaagcaggg gctgatcacc tacaaaatcg
    13561 ccgcccacgc cgcggattta gccaaaggac atccgggcgc gcagatccgc gataacgcca
    13621 tgtcgaaagc gcgctttgaa ttccgctggg aagatcagtt taacctcgcg ctcgacccgt
    13681 tcaccgcccg cgcttatcac gatgaaaccc tgccgcagga gtccggtaag gtcgcccact
    13741 tctgttccat gtgtgggccg aagttctgct caatgaaaat cagccaggaa gtgcgtgatt
    13801 acgccgccgc gcaagccatt gaagtcggca tggcggatat gtcggagaac ttccgcgcca
    13861 aaggcggcga aatttatctc aaacgggagg aagcctgatg tatcagcctg atttcccaac
    13921 cgtgccgttc cgcctcgggc tttacccggt ggtggacagc gttgcatgga ttgaacgcct
    13981 gctggaggcg ggcgtgcgca ccatccagtt gcgtatcaaa gataagcgcg atgaagaggt
    14041 ggaagccgac gttatcgccg ccatcgcgct ggggcgttgt tatgacgccc gcctgttcat
    14101 caatgattac tggcgtctgg caattaagca caacgcctac ggtgtacatt tgggccagga
    14161 agatctcgaa accactgacc tgaaggcgat tcaggcggcg gggttacgcc tgggcgtatc
    14221 gacccacgat gatatggaga tagacatcgc actcgccgct aagccttctt atatcgcgct
    14281 gggtcatgta ttccccacgc aaaccaagca gatgccttcc gccccacagg ggctggcgca
    14341 gctggcgcgg catattgaac gactggcgga ttatcccacc gtcgctatcg gcggcatcag
    14401 ccttgaacgc gctccggcgg tactagcgac cggcgtcggc agtattgccg tggtcagcgc
    14461 cattactcag gctgccgact ggcgcgccgc taccgcgcag ttactggcaa tcgcgggagt
    14521 gggcgatgaa tgaccgcgat tttatgcgct acagtcggca aatcctgctc ggcgatatcg
    14581 cgattgaagg ccagcaaaag ctgctcaata gccatgtatt gattgtcggc ttaggcggat
    14641 tgggttcgcc tgccgcgctg tatctggcgg gagcaggcat cggcacactg acgctggcgg
    14701 atgatgacga tgttcacttg agcaatctcc agcggcaaat tctgttcacc accgacgata
    14761 tcgcgcgttc gaaatcccag gttgcccagc agcacctgac acggctcaac ccggatatcg
    14821 aactggtatc actccagcag cgactaaaag gcgatgcgct ccggcatgcg gtagcgcgtg
    14881 ccgacgtggt gctcgactgt accgacaaca tggcgacccg tcaggaaatt aacgccgcct
    14941 gcgtggcact caacactccg ttaattaccg ccagcgccgt tggttttggc ggccaagtga
    15001 tggtcctcac gccgccgtgg gaacaaggct gttaccgctg cctgtggcca gatgatgtgg
    15061 agcctgaacg caactgccgt accgccggta tcgtcggacc ggttgttggc gtgatgggca
    15121 ccttacaggc gctggaagcg attaaattac tcagcggtat tgagacgccc agtggagagc
    15181 tacgcctgtt tgacggtaaa accagccagt ggcgcagcct ggcgctgcgt cgtgccagcg
    15241 gctgtccggt atgcggaggg cgacatgcaa attcaattca atgacgagcc gatgcagtgc
    15301 gccgaagggc aaaccgtcag cagcctactc gctacgctta atcagcttca accgggcgcg
    15361 gcgctggcgc tcaatcagca gatcctgcca cgcgagcagt ggcggcaaca tatcgtgcag
    15421 gaaggcgacc agatcctgct ttttcaggtt attgcaggag gttgagatgt tacgtattgc
    15481 cgacaaaacg tttgattcac atctgttcac cggtaccggg aagtttgcct catcgcaact
    15541 gatggtcgag gcaattcgcg cttccggcag ccaactggtg acgctggcga tgaagcgcgt
    15601 ggacctgcgc cagcacaatg atgcgattct ggcgccgctg attgaagcgg gcgtcacgct
    15661 gctgcccaat acctccgggg cgaaaaccgc cgaagaggcg atcttcgctg cccagctggc
    15721 gctcgaagcg ctgggcaccc actggctgaa attagaaatc cacccggacg cccgttggct
    15781 gctgccggat ccaatcgaaa cgctgaaagc cgccgaggcg ctggtgaagc aaggttttgt
    15841 ggtgctgccc tactgcggcg cggatccggt gttgtgcaag cggctggaag aggtcggctg
    15901 cgcggcggtg atgccgcttg gcgcgcctat cggttcgaat caggggctgg aaaccaaagc
    15961 gatgctggag attattatcc aacaggcgac cgtgccggtg gtggttgatg cgggcattgg
    16021 cgtgcccagc catgccgcgc aggcgctgga aatgggcgct gatgcggtgc tggtcaacac
    16081 ggcgattgcc gtggcggacg atccggtgat gatggcaacc gctttccgtc tggcggtgga
    16141 agccggatta ctggcgcgtc aggcggtgcc gggtaatcgt agcacctacg ccagcgctac
    16201 cagcccgctc accggatttc tggaggcgtt agcatgaaag ccttcaccga ccgttggcgg
    16261 caactggagt gggacgatat tcgcctgcgc atcaacggta aaaccgccgc cgatgtggag
    16321 cgggcgctga atgcttcacg cctcaaccgc gaggatatga tggcgttgct ctcccccgcc
    16381 gccgccgatt atctggaacc gatggcgcag cgggcacaaa ggctgacccg acaacgcttt
    16441 ggcaacaccg tcagtttcta cgtgccgctc tatctctcaa acctctgtgc caacgactgc
    16501 acctactgcg gcttctctat gagcaaccgc atcaagcgta agacgctgga tgaggtggat
    16561 attcaaaggg agtgcgatgc tatccgtaaa ctgggttttg agcatctgct gttagtcacc
    16621 ggcgagcatc aggccaaagt cggcatggac tattttcgcc gtcatttacc caccatccgc
    16681 cgtcaatttt cctctttaca gatggaagtc cagcccttgt cgcaagaaaa ctacgcggag
    16741 ctcaaaacgc tggggatcga tggcgtgatg gtttatcagg aaacttacca tgaggcaatc
    16801 tatgcacagc atcacctgaa gggaaagaaa caggactttt tctggcggct ggaaacgccg
    16861 gatcggttag gccgggcagg tatcgacaaa atcggtcttg gcgcgctaat tggtctgtcg
    16921 gacaactggc gggtggattg ctatatggtg gcggagcatc tgttgtggat gcagaaacac
    16981 tattggcaga gtcgctattc tgtttccttc ccgcgtctgc gtccgtgtac cggcggtgtg
    17041 gaacccgcat ctgtgatgga tgaaaagcaa ctggtgcaaa cgatttgcgc gtttcgttta
    17101 ctggcgccag aaattgaatt atcactctcc acccgcgaat cgccgtggtt tcgagaccat
    17161 gtgattcctc tggcaatcaa caacgtcagc gccttctcga aaacccagcc cggtggctac
    17221 gctgacgatc atccggaact ggagcagttt tctccccacg atgaccgtcg gccagaagtc
    17281 gttgcaagcg cgttaagcgc gcaagggtta cagcccgtat ggaaagactg ggacagttgg
    17341 ctggggcgcg cttcgcaaat gcggtgaacc cgtatgtaaa cgcattaata tttcacgagc
    17401 gagtacgtaa tgtgaaaaac gggagattgt tatcggcctc ccgtttttta ttttgtcatc
    17461 gtcagcaacg gaagctgacc agggcaaatt atcccttcct catttttgcc cagccttctc
    17521 cccttcatca gtaactgacg accgggggct ggccactgga ttatcgaaat agcggtgaac
    17581 ttgaagtttt cgggcagcgt tcctgactgt aatttcgctg gcggcccctc ttccaaccgt
    17641 gtctgctgat cgtttttgtc cataaaatga tgccccagaa caacgggaat caggggcgaa
    17701 cccatcaggg aaaaatgtgt tgcggccgga cgccgatggt aacgttactt gatggaaaac
    17761 gcatctgggc tgagaaaaat ttaagccaga tgtaatctga cagatatctg tataaataac
    17821 cggtaactgt cagatcaggt ctgagataat acatatcatt ttacctatac gcactacatc
    17881 ctcggacatc tgggattggt gcattatccg attataaagt cgtctgtgtg ttttttcggc
    17941 ctaaagacct taatggaatt gaatccttca tctaatgatt taaaatgtcc cgcgtaaaca
    18001 atcaataaaa caggtttatc atttaatgta tgaacagcag gcattttata atggcgagcc
    18061 aatagacttt aataacttag atttatggga taaatttaaa gtcacatttg gactaaatgt
    18121 tacagaaaaa accaaaccca atggtaaaaa atttcaattt tgagtattgt ggattctcta
    18181 cttttattac gccggttgat ggcgttggcg ggattttagc aaagtggctc tcaaacaaac
    18241 ataatgtaag tgtcccaacg ccttatacat tcggtcagga ccccattcct ggcatcaatc
    18301 tttatcgtaa tacaaaagca aaatttgtta tggctaacgg tggtaatagt cttccctgtg
    18361 cgatatcaaa atataatgca aaaactggac agtttattca tataaccagt gataatgatt
    18421 tttcaccaat aatacgagaa acaagagtca tgaaaa
//
LOCUS       DAJVKX010000085        18208 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.085, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000085 DAJVKX010000000
VERSION     DAJVKX010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18208
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.085"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(195..1559)
                     /gene="ppnN"
                     /locus_tag="OPY25_003014"
                     /gene_synonym="ygdH"
     CDS             complement(195..1559)
                     /gene="ppnN"
                     /locus_tag="OPY25_003014"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HCS0928575.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSCFENFDINVLRRERGVKLELINPPEDAFVDGRIIRALQANLFAVLR
                     DILFVNGQIHNAGRFQHLDLESSTHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGTQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKNQVLPLILTGPKESADYFRVLDEFITHTLGEAARRHYRIIIDDAAEVARLMKKAMP
                     QVKENRRDTGDAYSFNWSMRIAPDLQVPFEPSHENMANLKLYPDQPVEILAADLRRAF
                     SGIVAGNVKEVGIRAIEANGPYKIHGDREMMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICA"
     gene            complement(1673..2521)
                     /gene="queF"
                     /locus_tag="OPY25_003015"
     CDS             complement(1673..2521)
                     /gene="queF"
                     /locus_tag="OPY25_003015"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HCS0928576.1"
                     /translation="MSSYENHQALDGLTLGKSTDYRDNYDASLLQGVPRSLNRDPLGL
                     TADNLPFHGADIWTLYELSWLNSQGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFDTWETVRQTLERDLRACAQGNVSVRLHRLDELEGQPVAHFHGTCIDDQDISIDNY
                     QFTTDYLQHAVSGEKQVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRKIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDILRFCQPETLSVYARYTRRGGLDINPWRSNTDFVPAT
                     GRLARQ"
     gene            2590..3135
                     /gene="syd"
                     /locus_tag="OPY25_003016"
     CDS             2590..3135
                     /gene="syd"
                     /locus_tag="OPY25_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HCS0928577.1"
                     /translation="MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISS
                     TRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQ
                     TWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGT
                     RNRTVLAATLAEFLTQLNPLL"
     gene            3745..4074
                     /locus_tag="OPY25_003017"
     CDS             3745..4074
                     /locus_tag="OPY25_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HCS0928578.1"
                     /translation="MTTHDRVRQQLHALETLLREHRHWRLDAPQAHLFTSTQPFFMDT
                     MEPLEWLQWVLIPRMHTLLDNAQPLPEAFAVAPYYEMALAADHPQREAILAVLQDLDA
                     LFVRDKS"
     gene            4074..4856
                     /gene="truC"
                     /locus_tag="OPY25_003018"
     CDS             4074..4856
                     /gene="truC"
                     /locus_tag="OPY25_003018"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HCS0928579.1"
                     /translation="MLEILYQDPWLVAVNKPAGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRRLAQQFEQHHIRKRYHAIVRGWLIDDAVLDY
                     PLVEERDKIADKFAREDKAPQPAVTQYRGLATVEMAVPTGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSAAEHFACRRLMLHASRLELTHPFTGQPLI
                     IQAGLDETWMQVLTQFGWRGLLPDNERVEFTAASRQDETHLT"
     gene            4875..5324
                     /locus_tag="OPY25_003019"
     CDS             4875..5324
                     /locus_tag="OPY25_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCS0928580.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILARQGHSATVFEDPELSDW
                     QQYQDKVALVVTSTTGQGDLPDSIAPLFHGIKDTLGFQPNLRYGVIALGDSSYPNFCN
                     GGKQFDALLQEQSAQRVGEILFIDASEHPEPESQSNPWVENWGTLLS"
     gene            complement(5474..5722)
                     /locus_tag="OPY25_003020"
     CDS             complement(5474..5722)
                     /locus_tag="OPY25_003020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928581.1"
                     /translation="MQLLLGRLLCTLHAFIHWQEKYKKRATHTHRATTQYFGDELRLF
                     MAKAQDSGSHFTEMKSEGVGVDAGGVKREECETGRLIT"
     gene            5805..7163
                     /gene="gudP"
                     /locus_tag="OPY25_003021"
     CDS             5805..7163
                     /gene="gudP"
                     /locus_tag="OPY25_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HCS0928582.1"
                     /translation="MSSLSHAASSAEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSVFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAESPSFPGNSRIVAAWFPAQERGTAVAIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIIISFIWLKVIHEPNNHPGVNKKELEYI
                     AEGGALINMDQKDTKAKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGFLNIARKTPIVLGM
                     LLSMVMVFCNYVNVEWMIIGFMVLAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALVAIISYLVLVGDIKRIELKPVAGQ
                     LS"
     gene            7160..8500
                     /locus_tag="OPY25_003022"
     CDS             7160..8500
                     /locus_tag="OPY25_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HCS0928583.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGVGETPGGEVIYQTLVDAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLQGQALNVPVCELLGPGKQRDAVTVLGYLFYIGDRTKTD
                     LPYLESTPGSHEWYRLRHQEALNSDAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAIALCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLTGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGKPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVRKAHDAYKKLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            8521..9861
                     /gene="gudD"
                     /locus_tag="OPY25_003023"
     CDS             8521..9861
                     /gene="gudD"
                     /locus_tag="OPY25_003023"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HCS0928584.1"
                     /translation="MSTQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIVK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLDEYKNVLTAVRNQFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKVT
                     PLPYQSQPDEQCDWYRLRHEEAMTPETVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAKRFPQARVTLDPNGAWSLNEAISIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGMVQV
                     PTKPGLGVELDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            9939..11081
                     /locus_tag="OPY25_003024"
     CDS             9939..11081
                     /locus_tag="OPY25_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCS0928585.1"
                     /translation="MKIVIAPDSYKESLSALEVATAIEQGFREIWPDADYLKLPLADG
                     GEGTVEAMVEATAGRIVHVEVTGPLGHRVNAFYGLSGDARSAFIEMAAASGLEQVPPA
                     QRDPLKTTSWGTGELIRHALDAGVEHIIIGIGGSATNDGGAGMVQALGARLRDAQGND
                     IAQGGIGLETLASIDISGLDKRLSACHIEVACDVTNPLTGKEGASAVFGPQKGATPEM
                     IERLDTALTRYAHLIARDLHVDVLDLAGGGAAGGMGAALYAFCGAQLRRGIEIVTDAL
                     HLEACLADADLVITGEGRIDSQTIHGKVPIGVANIAKRYNKPVIGIAGSLTADVGVVH
                     EHGLDAVFSVIYTICTLEDALKNASENVRMTARNVAATLKAGQQLR"
     gene            complement(11125..13881)
                     /gene="barA"
                     /locus_tag="OPY25_003025"
     CDS             complement(11125..13881)
                     /gene="barA"
                     /locus_tag="OPY25_003025"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HCS0928586.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSSEYGMNLQNRESIGQLISVLHRRHSDIVRAISVYDDHNRLFVTSNFH
                     LDPSQMQLPAGAPFPRRLSVDRHGDIMILRTPIISESYSPDESAIADAKNTKNMLGYV
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELNPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRNTLDEVVTLLAHSSHDKGLELTL
                     NIKNDVPENVIGDPLRLQQVITNLVGNAIKFTESGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNVIIDGPSTACLAGKRLAYIEPNATAAQCTLDLLSDTPVEVIYS
                     PTFSALPLAHYDIMILSVPVTFREPLTMQHERLAKAASMTDFLLLALPCHAQINAEKL
                     KQGGAAACLLKPLTSTRLLPALTEYCQLNHHPEPLLMDTSKITMTVMAVDDNPANLKL
                     IGALLEDKVQHVELCDSGHQAVDRAKQMQFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLSAGMNDYLAKPIEEEKLHNLLLRYKPGANVAARLMAPE
                     PAEFIFNPNATLDWQLALRQAAGKPDLARDMLQMLIDFLPEVRNKIEEQLVGENPNGL
                     VDLVHKLHGSCGYSGVPRMKNLCQLIEQQLRSGVHEEELEPEFLELLDEMDNVAREAK
                     KILG"
     gene            13939..15234
                     /gene="rlmD"
                     /locus_tag="OPY25_003026"
     CDS             13939..15234
                     /gene="rlmD"
                     /locus_tag="OPY25_003026"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCS0928587.1"
                     /translation="MAQFYSAKRRVTTRQIITVKVNDLDSFGQGVARHNGKALFIPGL
                     LPEESAEVIITEDKKQFARARVSRRLNDSPERETPRCPHFGVCGGCQQQHVGIDLQQR
                     SKSAALARLMKHEVNDIIAGASWGYRRRARLSLNCPPDKPLQMGFRKAGSSDIVNVEQ
                     CPVLAPQLEALLPRIRACLASLHGTRHLGHVELVQAGSGTLMILRHTAPLSAADKEKL
                     ERFSHSEGLSLFLAPFSEILETVSGEAPWYDSHGLRLTFSPRDFIQVNEAVNQQMVAR
                     ALEWLDVRAEDRVLDLFCGMGNFTLPLATRAASVVGVEGVQALVEKGRENAIRNGLHN
                     VTFFHENLEEDVTKQPWAKNGFDKVLLDPARAGATGVMRHIIKLKPIRIVYVSCNPAT
                     LARDSEALVNAGYEVTRLAMLDMFPHTGHLESMVLFERM"
     gene            15286..17520
                     /gene="relA"
                     /locus_tag="OPY25_003027"
     CDS             15286..17520
                     /gene="relA"
                     /locus_tag="OPY25_003027"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP diphosphokinase"
                     /protein_id="HCS0928588.1"
                     /translation="MVAVRSAHINKAGEFDPKKWIASLGISSQQSCERLAETWAYCLQ
                     QTQGHPDADLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     IVTLIHGVRDMAAIRQLNATHNDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKEAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPAEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKNEGVQAEVYGRPKHIYSIWRKMQKKHLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAASGGVRSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQVEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELAHLGISLKEAEKHLLPRYNFNELEELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKTYAPQNRRKDDGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVEAVWGESYSAGYSLVVRVQANDRSGLLRD
                     ITTILANEKVNVLGVASRSDIKQQIATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGG"
     gene            17605..17961
                     /locus_tag="OPY25_003028"
     CDS             17605..17961
                     /locus_tag="OPY25_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461876.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HCS0928589.1"
                     /translation="MFLTYISFQVYSYVRFILTVEAVMARTMTVDLGDELREFIESLI
                     ESGDYRTQSEVIRESLRLLREKQAESRLQALRELLAEGLNSGEPQAWEKDAFLRKVKT
                     GMIKPDENGKINAKGQ"
     gene            17927..18208
                     /locus_tag="OPY25_003029"
                     /pseudo
     CDS             17927..18208
                     /locus_tag="OPY25_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220181.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT         4231 a         4599 c         5159 g         4219 t
ORIGIN      
        1 aatcacggta agaggagtca ggtaaacgtt tgcctggcaa tctatttatg gtaaattata
       61 aatggtgttt ataaaacaat gcgggctata cctctgatga tcatcataaa aaatgaaggc
      121 atacgtgaat cgccataccg caatgaaagg aatgggagaa gcgcccggct gctggcggca
      181 accgggcata agcgttaagc gcagatctcg taacagggga tgtaggcgga acccggcaat
      241 ttcatacgat gctgcgcgac gaatccctgc agcagatcgt ccatgcgacg catcatctct
      301 cgatcgccgt ggattttata cggaccatta gcttcaatgg cgcgtatccc gacctccttc
      361 acgttccccg cgacaatacc ggagaaggcg cgccgcagat ccgccgccag aatctcaacc
      421 ggctgatccg ggtacagttt caggttggcc atattctcat gcgacggctc aaacggcacc
      481 tgcagatccg gtgcaatacg catcgaccag ttaaaactat aggcgtcgcc agtatcgcgg
      541 cgattctctt tcacttgcgg catcgctttc ttcatcagcc gcgctacctc cgccgcatcg
      601 tcaatgatga tgcggtaatg acggcgggcc gcttcgccca gcgtatgggt aataaactca
      661 tccagcacgc ggaagtaatc ggcgctctct tttggtccgg tcaggatcag cggcagcacc
      721 tgatttttat tggctggatt catcagaatc cccagcaaat aaagcagctc ttccgccgta
      781 cccacgccgc ccgggaagat gatgataccg tgtgcgatac ggacgaacgc ttccaggcgt
      841 ttttcgatat ccggcatgat gatcagttcg ttcaccagcg ggttaggcgg ttcagccgca
      901 ataatggaag gttcagtcat gccgataaag cggctgtctt tatagcgctg ctgtgcgtga
      961 ccgaccgccg cgcccttcat gggggcttcc atcgccccag ggccgcagcc ggtgcagatg
     1021 ttcagctcgc gtaatcccaa ctgcgtgccg acgcgacggg catacaggta ctcgttttcg
     1081 ttaattgagt ggccgcccca gcataccacc atgtttggcg cttcgccgac gtgcagcgcc
     1141 cgggcgttgc gcaaaatgga gaacaccaga ttggtgatat gtgttgagct ttcaagatcc
     1201 agatgctgga aacggccggc attgtggatc tgcccattca caaagagaat gtcgcgcagc
     1261 actgcgaaca ggttagcctg tagcgcacga ataatccgcc cgtcaacaaa ggcgtcttca
     1321 ggcggattaa tcaattccag cttcacgccg cgctcgcggc gcagtacgtt aatatcgaaa
     1381 ttttcaaagc aggacagcag ctctttgctg ttgtcggtca ggctgccgga gttaagaacg
     1441 gcaagtgaac agttacgaaa cagttgatac aggtcgctac tggccgtgcg tttcagcatg
     1501 tccacttcca gttgcgacaa catatccatt gagccaagcg ggctaatatg tgtaatcaag
     1561 taaactcctt atgggacgca acacgccatt ccctgttgat tacaatagcc ctggctgatg
     1621 acctttcaca accttacatg cgcaatccgg cacgcaaaat tgacaaaaaa gattactgac
     1681 gcgccagcct gcccgtggcg ggcacaaaat cggtattgct gcgccaggga ttaatgtcca
     1741 gcccgccgcg gcgggtatag cgtgcataaa cgcttaacgt ttccggctgg cagaagcgca
     1801 gaatgtcatt gaaaatacgc tctacgcact gctcgtgaaa ttcattatgg tgacggaagg
     1861 agaccagata acgcagcagt ttttccctgt cgattttgcg cccgcgatac tgaatttgta
     1921 tcgagcccca gtccggttgg tgggtgatca ggcagttgga tttcaacaga tgactgacca
     1981 gcgtttcttc tacttgcttc tcgccgctga ccgcatgttg cagatagtcg gtagtaaact
     2041 ggtagttgtc gatactgata tcctgatcgt caatacaggt gccgtggaaa tgggcgacag
     2101 gctgtccttc cagctcatca agacgatgaa gcctcacgct aacgttgccc tgcgcgcagg
     2161 cgcgcagatc gcgctccagc gtctggcgca ccgtctccca ggtgtcaaag cgcgtctggt
     2221 taaagctgtt cagatacagt ttaaaacttt tggattcgat taaattaacg ctggtgtaat
     2281 ccagttcgac atgtccgacg gcgacctgcg gaagaccctg gctgttaagc caggaaagtt
     2341 catacaacgt ccagatatcc gcgccgtgga acggcaaatt atcggctgtt aatccgagcg
     2401 ggtcgcgatt caaactgcgc ggtacgccct gcagcaggct ggcgtcataa ttgtcccggt
     2461 aatccgttga ttttccgaga gtcaggccat cgagagcctg atggttttca taagaagaca
     2521 tgtttcaccg tcataaacca gatacactat gcgtcaagtg tatcctggct tttatgaaga
     2581 gagaaactgg tggacgaact gacagcgcag gcattgaaag cctttacgac gcgttactgc
     2641 gacgcgtggc aagaaaaaca cggtagctgg ccgttgagcg aagaactgta tggcgtacct
     2701 tctccgtgca ttatttcttc aacccgcgat gccgtttact ggcagccgca gccttttgaa
     2761 ggcgaagaaa atgtaaacgc ggttgaacgc gcctttgata ttatggtaca acctgcgctc
     2821 cacgcgtttt acaccacgca gtttgctggc gacatgcccg cgcagtttgc ggatgaaaag
     2881 cttacgctac tgcaaacctg gagtcaggat gactttcggc gcgtgcagga aaatctgata
     2941 ggccacctgg tcacgcaaaa gcggctcaag cttcctccca cgctttttat tgcgacgcag
     3001 gaaaatgagc ttgaggtcat ttcggtctgt aatctgtccg gcgaggtgat taaagaaacg
     3061 ctgggcaccc gcaatcgtac cgttcttgcc gcaacgcttg cggaattcct tacgcaactt
     3121 aatcctcttc tgtaatcgtt tgccctaacg ggtgtgagag atctcttaca aagtctgtag
     3181 gagatcgcca ggatatcagc ggatactgag ccccgttttc ttatgtaagt ctatataaaa
     3241 caactaatta aaatgttttt gcgcactttc atatgaaaat ttacttaagg tattgtctgt
     3301 aagcgtcttg taagacaagg tgaaacaggc gattctatct tcgtcgacag ggagtcgtac
     3361 aacgaagcga acgtcaggat gatgacgctt cagcaggaca cgccaggatg gtgttacaag
     3421 gaaaggcttc aggatgaagc aaagtggaaa gcgcaggatg cgttaaagga cacctccagg
     3481 acggagaacg agagccgatc aggatgttcg gcggatctgg ataaccaggg acgcttcagg
     3541 atgaagctat cacatcgggc gatgtgcgca ggatgtaaac gttcaggatg aacaggccgt
     3601 aaggtcacag gaaaagttgt cacggatgag cagggagcac gaaaagtagc tggaatgctg
     3661 cgaaacgaac cgggagcact gtttatacag tgctcccttt ttttgttatt cttcgcgcca
     3721 gattttcatc attgaggttt taacatgacg actcatgacc gtgtgcgtca gcagttacat
     3781 gcgcttgaaa cgctgctgcg cgagcatcgc cactggcggc tggatgcgcc gcaggcgcat
     3841 ttgtttacca gcacccaacc attttttatg gataccatgg aaccgctgga atggctgcaa
     3901 tgggtattga tcccacgtat gcatacccta cttgataatg cgcagccgct gcccgaggcg
     3961 tttgccgtcg ccccttatta tgaaatggcg ctggcggcgg atcatccgca gcgggaggcg
     4021 atcctggcgg ttttgcagga tctggatgcg ctattcgtcc gcgataaatc ctgatgctgg
     4081 agatcctcta tcaagacccg tggctggttg ccgtgaataa acccgcaggc tggcttgttc
     4141 accggagctg gctggatcgc gacgaaaaag tcgtggtcat gcaaacggtg cgcgaccaaa
     4201 tcggccagca tgtttttacc gcccaccgtc tcgacaggcc cacgtcgggc gtactgttaa
     4261 tggggctgtc cagcgaagcg ggacgccgtc tggcgcagca gttcgagcag caccacatcc
     4321 gtaaacgcta ccatgccatt gtgcgcggct ggctgataga tgacgcggta ctggattatc
     4381 cgctggtgga agagcgcgat aaaattgccg ataaattcgc ccgcgaagat aaagcgcccc
     4441 agccggctgt aacgcagtat cgcgggctgg cgacggtcga aatggcggtg ccgaccgggc
     4501 gttatcccac cacgcgttat ggcctggttg agctggaacc aaaaacggga cgcaagcacc
     4561 agcttcgtcg tcatctggcg catctgcgtc atcctatcat cggcgacagc aagcatggcg
     4621 atttgcgaca aaaccgcagc gccgcagagc attttgcctg tcgtcgcctg atgcttcatg
     4681 ccagtcggct tgaactgacg caccccttca ccggacagcc gttgataatt caggccgggt
     4741 tggatgaaac ctggatgcag gtgctgacac agtttggctg gcgtggactt ctccctgaca
     4801 atgaaagggt tgagtttacg gcggcgtccc ggcaggatga gactcatctg acataattca
     4861 gggagatacg cataatggcg gaaattggta tttttgtcgg gaccatgtat ggcaactcac
     4921 tgctggtggc ggaagaagcg gaagcgatcc tcgccagaca gggccacagc gcgaccgtgt
     4981 ttgaagatcc tgaactgtcc gactggcagc aatatcagga taaggttgcg ctggtcgtta
     5041 cctcgacgac cgggcaaggc gatctaccgg atagcattgc gccgctcttt cacggcatta
     5101 aagatacgtt gggttttcag ccaaacctgc gttacggggt gattgcgcta ggtgatagca
     5161 gctaccccaa tttctgtaat ggcggcaaac agtttgatgc cctgttgcaa gagcaaagcg
     5221 cgcagcgggt gggggagata ttattcattg acgccagcga acatccggag ccggagagcc
     5281 aatccaatcc ctgggttgaa aactggggaa ctttactttc ctgaggtaaa tccctccccc
     5341 ctacgggagg gtaccttttc gtttgcttgc gttgccagta agcaaaatca cgacctgtac
     5401 acagtgtaaa gtaactgaat cgtgttagct ttgggcatat gcccgcaaaa gcggcagttt
     5461 tttacgggcg ttttcatgta atcaagcgac ctgtttcaca ttcttctctt tttactcctc
     5521 ctgcgtcgac gccgacgcct tctgatttca tttccgtgaa gtggcttcca ctgtcctggg
     5581 cttttgccat aaacaggcgt aattcatcgc caaaatactg tgttgttgca cggtgagtgt
     5641 gtgtggcgcg ctttttatac ttctcctgcc agtgaataaa agcatgcagc gtgcaaagca
     5701 aacgacctaa taaaagctgc aacaaggaaa cgttatctct gattccctac cggttgtgca
     5761 gttcagagtg agcgtagcta acgcgaaatt tcaggagtgc aacaatgagt tcattaagtc
     5821 acgcggcgag cagtgcggag aaacgcacga acgcccgcta ctggatagtg gtgatgctgt
     5881 ttatcgtcac atccttcaac tacggcgacc gcgccacatt gtccattgcc ggctcagaaa
     5941 tggccaaaga tatcggcctt gatccggtag gtatgggcta tgttttttct gctttttcat
     6001 gggcctatgt tatcgggcag atcccgggcg gctggctgct ggaccgcttt ggttccaaac
     6061 gcgtctattt ctggtctatt ttcatttggt cagtcttcac cctgttgcag ggttttgtcg
     6121 atatctttag tggtttcggc attattgtcg ccctctttac gcttcgtttc ctggtcggtc
     6181 tggcggaatc gccttctttc ccgggcaaca gtcgcatcgt tgcggcctgg ttcccggcgc
     6241 aggagagggg aacggcggtg gccatcttta actccgcgca atactttgcc acggttattt
     6301 tcgcgccgat tatgggctgg ctgacgcacg aagtgggctg gtcgcatgtc ttcttcttta
     6361 tgggcgggtt agggatcatc atcagcttta tctggttgaa agttatccat gaaccaaata
     6421 accatccggg cgtaaataag aaagaattgg agtacatcgc agaaggcggc gcgctgatca
     6481 atatggatca gaaagacacc aaagcgaaag taccgtttag cgtcaaatgg ggccagatca
     6541 aacagctgct gggctctcgt atgatgattg gcgtttacat cggtcagtac tgtattaacg
     6601 cattgaccta tttctttatt acctggttcc cggtctattt ggtccaggcg cgcggcatgt
     6661 cgattctcaa agcgggcttt gtcgcctcgg ttcctgcagt ctgcggcttt atcggcggcg
     6721 tgttgggcgg catcatttcc gactggctga tgcgtcgtac tggcttcctg aatatcgcgc
     6781 gcaagacgcc gattgtgctg ggaatgttgc tgtcaatggt tatggtgttc tgtaactatg
     6841 tgaacgtgga atggatgatc atcggcttta tggtgttggc cttcttcggt aaaggtattg
     6901 gcgcgttggg ctgggcagta atggcggata ccgccccgaa agagatcagc ggtctttccg
     6961 gcggcttgtt taatatgttc ggcaatattt ccggtattgt gacgccaatc gcgattggtt
     7021 acatcgttgg caccaccggt tccttcaacg gcgcgttgat ctatgtcggc gtacatgccc
     7081 tggtggccat catcagctat ctggtgctgg taggcgatat taagcgtatt gaactgaaac
     7141 ctgtcgcagg acaattatca tgacaacgca atccagtccc gttattacgg acatgaaggt
     7201 cattccggtt gccggacatg acagtatgct actcaacatc ggcggcgcgc ataacgcgta
     7261 cttcacccgt aacatcgtcg tcctcaccga taacgccggg catactggcg tcggcgagac
     7321 gccgggcgga gaagtgattt atcagacgct ggtcgatgct attccgatgg tattaggcca
     7381 ggaagtcgcc cgcctgaaca aagtggtgca gcaggtgcat aaaggcaacc aggccgctga
     7441 ttttgacacc tttggcaaag gcgcatggac gtttgaactg cgggttaacg cggtggcggc
     7501 tttggaagcg gcgctgcttg atctacaggg acaggcgctt aatgtgccgg tctgtgaact
     7561 gttagggcca ggtaaacagc gcgatgccgt caccgtgttg ggctatctct tctatattgg
     7621 cgatcgcact aaaaccgatc tgccgtatct ggaaagcacg ccgggcagtc atgaatggta
     7681 tcgtctgcgc catcaggaag cgctgaacag cgacgcggtc gtgcggctgg cggaagcgtc
     7741 tcaggatcgc tacggcttta aagattttaa actcaagggc ggcgtgctgc cgggcgaaca
     7801 agagattgat accgttcgcg cgctaaaaaa acgcttcccg gacgcgcgta ttaccgtgga
     7861 tccgaacggc gcctggctac tggatgaagc cattgcgttg tgcaaagggc tgaatgatgt
     7921 actgacctac gcggaagatc cgtgcggcgc ggagcaagga ttctctggtc gtgaagtcat
     7981 ggcggagttc cgccgcgcga caggactgcc ggtggcgacc aatatgattg ccaccaactg
     8041 gcgtgaaatg ggacacgcgg tgatgctcaa cgcggtagat attcctcttg ccgacccgca
     8101 tttctggacc cttaccggcg ccgttcgcgt ggcgcaactg tgcgatgact gggggctaac
     8161 ctggggctgc cattcgaata accattttga tatttcactg gcgatgttta cccatgtcgg
     8221 cgcggcggcg ccaggcaaac ccaccgctat tgatacgcac tggatctggc aggagggcga
     8281 ttgccgcctg actaaaaatc cgctggaaat taaaaacggc aaaattgccg ttccggatgc
     8341 gccaggactg ggcgtagagc ttgactggga acaggtgcga aaagcgcatg acgcgtataa
     8401 aaagctgcca ggcggcgcgc gtaatgatgc aggcccgatg caatacctga tccccggctg
     8461 gacttttgac cgcaaacgcc ctgtttttgg tcgtcactaa ttctgaataa ggacacagtt
     8521 atgagtactc aatttaccac gcctgtagtg actgaaatgc aggttatccc ggttgcgggt
     8581 catgacagta tgctgatgaa cctgagcggc gcgcacgccc cgttctttac gcgcaacatc
     8641 gtcattgtta aagataactc cggtcatact ggggtcggcg agattccggg cggcgaaaaa
     8701 attcgcaaaa cgctggaaga tgcgattcca ctggtggtgg gaaaaacgct ggatgaatat
     8761 aaaaatgtcc tgaccgccgt tcgcaaccag tttgccgatc gcgatgcggg cggacgcggt
     8821 ttacaaacgt tcgatctccg taccactatc catgtggtga cgggcattga agcggcaatg
     8881 cttgaccttt tgggccaaca tctgggcgtc aacgtcgctt cgctgttagg cgacggtcag
     8941 cagcgcagcg aagtcgaaat gctgggttat ctgttctttg tcggcaatcg caaggttacg
     9001 ccgctgccgt atcaaagcca gccggatgag caatgcgact ggtatcgtct gcgccatgaa
     9061 gaggcgatga cgccggaaac ggtagtgcgt ctggcggaag cggcgtatga aaaatacggc
     9121 ttcaacgact tcaaactgaa aggcggcgtg ctggcgggcg aagaagaggc cgagtcaatc
     9181 gtggcgctgg cgaaacgttt cccacaagcg cgcgtcacgc tcgatccaaa cggtgcctgg
     9241 tcgctgaacg aagcgatcag cattggtaaa tacctaaaag gttctctggc ctatgcagaa
     9301 gatccgtgcg gcgcggagca gggtttttcc ggtcgtgaag tgatggcgga attccgtcgc
     9361 gcgaccggat taccgacggc caccaatatg atcgccaccg actggcgtca gatggggcat
     9421 acgctgtcgc tgcaatccgt cgatatcccg ctggcggacc cgcacttctg gactatgcaa
     9481 ggctctgtac gcgtggcgca aatgtgtcat gagttcggcc tgacttgggg ctcgcactct
     9541 aacaaccact ttgatatttc actggcgatg tttacccatg ttgccgcggc ggcgccgggc
     9601 aagatcactg ctatcgatac ccactggatc tggcaggaag gcaaccaacg tctgactaaa
     9661 gaaccgtttg aaattaaagg cggcatggtg caagtaccga ccaaaccggg gctgggcgtt
     9721 gagctcgata tggatcaggt gatgaaagcg catgagctct atcaaaagca tggcttaggc
     9781 gcgcgtgacg acgcgatggg aatgcagtac ttaattcctg gctggacgtt tgataataag
     9841 cgcccttgca tggtgcgtta agtcagagcc ggttccgtaa ggaaccggtc cttctctggg
     9901 tgtatgctta acaggatcaa catgcgtaag gacgacttat gaaaatagtg atcgcaccag
     9961 attcgtataa ggaaagtttg agtgctcttg aggtagcgac cgccattgaa caaggatttc
    10021 gcgagatctg gcctgacgcg gattacctga aattaccgct ggctgatggc ggagaaggta
    10081 ctgtcgaagc gatggttgaa gcgacggcgg gtcgaatcgt gcatgttgag gtcaccgggc
    10141 cgttggggca tcgcgtcaat gcgttttatg ggctttccgg cgatgcgcgt tccgcgttca
    10201 ttgaaatggc ggccgccagc gggctggagc aggtgccgcc cgcgcaacgc gatccgttga
    10261 agaccacgtc atggggaacc ggcgagctga tccgtcatgc gctggatgcg ggcgttgagc
    10321 atatcattat tggtatcggc ggtagcgcca ccaacgatgg cggcgcgggg atggtacagg
    10381 cgctgggtgc caggctacgg gatgcgcagg gcaatgatat tgcgcaaggc ggcattgggc
    10441 tggaaacact cgccagcatt gatatcagcg gcctggataa gcgtttgtcg gcgtgccata
    10501 tagaggtcgc ctgcgatgtc acgaatcccc ttaccggcaa agagggcgcg tctgcagttt
    10561 ttggtccgca aaaaggggcg acgccggaaa tgattgaacg cctagatacg gcattgactc
    10621 gctatgcgca tttgattgcc cgcgatctgc atgtcgatgt gttggatctg gcaggcggcg
    10681 gcgcggcagg cggcatgggg gcggcgttat acgcgttttg cggcgcgcag ctacggcgtg
    10741 gtattgagat tgtcaccgat gcgcttcatc tggaagcgtg tcttgcggat gctgatttag
    10801 tcatcaccgg cgagggacgc atcgacagtc agaccattca cggtaaagtc cctattggcg
    10861 tggcaaacat cgccaaacgg tataacaagc cggtaattgg tattgcgggt agcctgacgg
    10921 cggacgttgg cgtggttcat gaacatgggc ttgatgccgt tttcagcgtg atttatacca
    10981 tctgcacgtt ggaggacgcg ctgaagaatg cgagtgaaaa cgtacgaatg accgcgcgca
    11041 acgtggctgc aacgctgaaa gcggggcaac aattacgctg agttgtaggc cggataaggc
    11101 ggtcacgccg ccatccggcg aatatcagcc taatatcttc ttcgcttcac gcgcgacatt
    11161 atccatctca tccagcagct ccagaaactc aggctccagc tcctcttcgt ggacgccgct
    11221 gcgaagctgt tgctcaataa gctggcaaag gttcttcatc cgcggtacgc cgctatagcc
    11281 gcagctcccg tgtagcttat ggaccagatc gaccaggccg ttgggattct ctcccaccag
    11341 ttgttcttca attttgttgc gcacttccgg cagaaaatca atcagcattt gcagcatatc
    11401 ccgtgccaga tcgggcttac cggcagcctg gcggagcgca agctgccagt cgagcgtcgc
    11461 attcggattg aagataaact cagccggttc cggcgccatc aggcgcgctg ctacgttggc
    11521 gccgggttta tagcgcagca acagattatg caacttctct tcttctatcg gtttagccag
    11581 atagtcgttc atgcccgcgc tgagcaactt ctctttttgc ccggccatcg catgtgccgt
    11641 aacggcaata accggtgttt gctgctgatg aggaagctgg tgaattaact cgcaggcgcg
    11701 tatgccgtcc atatccggca tctgaatatc catcaaaatc agatcaaact gcatttgttt
    11761 cgcccgatcc accgcctgat gtccgctatc acaaagctct acgtgctgga ctttatcttc
    11821 cagtaacgcg ccgataagct tcagattagc gggattatca tcaaccgcca taaccgtcat
    11881 ggtgatttta ctggtatcca ttagcagcgg ttcaggatgg tgattcaact ggcaatattc
    11941 tgtcagcgct ggcaacaggc gcgttgacgt caatggtttt aacagacagg ctgccgcgcc
    12001 tccttgtttc agcttttcgg cattaatttg cgcatggcaa ggtagcgcca gcagtagaaa
    12061 gtccgtcatt gacgctgctt tcgccagacg ttcatgctgc atggtgagcg gctcgcggaa
    12121 ggtcaccgga acgctcaaaa tcataatatc gtagtgcgct aacggcagcg cggagaaggt
    12181 cgggctgtaa atcacttcca ccggcgtgtc gctcagtaga tccagggtac attgcgcggc
    12241 ggtagcattc ggttcgatat aagccagccg tttcccggcc agacacgcgg tcgacggccc
    12301 gtcaataatg acatttgggt taagatcaag attaatatga aaccagaagg tcgagccgcg
    12361 attaggctgg ctgtggaaag agatatcccc gcccatttcg ttgaccagct tttgcgtaat
    12421 caccagccca agcccggtgc cgccgtgacg gcgagaaata ctggcatcgg cctggcgaaa
    12481 cgcctgaaac agtcgcgact ggtcgcgctc cggaatgccg atccccgtat cgcggatctg
    12541 cacttcaatc tgtactttgg tgttactgag cgcccgcttt tctaccagaa tgtcgatatt
    12601 gccactctcg gtgaacttaa tggcattgcc caccagatta gtaatgacct gttgcaggcg
    12661 cagcgggtcg ccaatcacat tttccgggac gtcgttttta atatttaacg tcaactccag
    12721 ccctttatca tgcgacgagt gggccagcag cgtaaccact tcatccagcg tgttgcgcag
    12781 tggaaaaggg atactttcca gaatgagctt accggcttcc agcttggaga agtcgagcac
    12841 gtcattaatg attgccagca gattattcgc ggaacgctca atggtgttca gatggtcgcg
    12901 ctgggtgggg ttcagctccg tttttaatgt caggcgggta aaaccaatga cgccgttcag
    12961 cggtgttcgc agttcgtgcg acatgttcgc caggaactcc gacttaatac gcgccgcttc
    13021 ctgggcgcgc tttttcgcca gatccagctc aacgttttgg atttccatct gctcaagggt
    13081 ttcacgcagg tccgaggtgg cctgatcgat attatgctgc atctcttcgt gataggcggc
    13141 aagcgacatc gccatggaat taatgccgtt tttcagcatg tccagctcgc ccagcataaa
    13201 tccttccaca cggctatcca gttgtccgcg gcgaatgcgg tcaacggtat tcaccatatt
    13261 acggataggc ccggtgacat cgcgcataag ccgccagcca aagatcagcg caatgccaat
    13321 acaaaaaagc atcatcacgc tggagataaa aatctctttg tattgctgta gcctgaccga
    13381 cttgagatcc agttcaagtg ccacataccc cagcatattt ttggtatttt tcgcgtcggc
    13441 aatcgctgac tcgtccggcg aatagctctc cgagataatc ggggtgcgca gaatcataat
    13501 atcgccgtgg cgatcaacgc tcagacgacg tggaaacggc gctccggcag gaagctgcat
    13561 ctgtgagggg tccagatgga aattagacgt tacaaacagg cggttatgat cgtcataaac
    13621 ggaaatcgcc cgcacaatat cagagtgtct gcggtgcagg acgctgataa gttggccgat
    13681 agactcccgg ttttgtaagt tcataccata ttcgctggag acggcgagcg gttcaataat
    13741 actggcgccg gcatcttcca gttgacgctg caggtcgtta tagcggtgca ctacaaaaaa
    13801 gatactgagc agcaaaccta tcaggacggt cggggccagg atcagaatca tcatgcgtgc
    13861 gcgcaggctg tagttggtca tggagttccg ttatgggaca attagggtca cactgttaaa
    13921 ttgagaaaaa gctggtcgat ggcgcaattc tactctgcaa aacggcgcgt gacgacgcgt
    13981 cagatcataa ccgttaaagt caatgacctc gattcatttg gtcagggcgt agcccgtcat
    14041 aacggaaagg cgctgtttat ccccggttta ttgcctgagg aaagcgcaga agtcattatt
    14101 acagaagata aaaagcaatt tgcccgcgca cgcgtttcgc gccgtttgaa tgatagcccg
    14161 gaacgagaaa cgccgcgctg cccgcatttt ggcgtctgcg gcggttgtca gcaacagcat
    14221 gtcggcatcg acctgcaaca acgcagcaaa agcgcggcgc tggcgcgttt aatgaaacat
    14281 gaggtgaatg acatcatcgc cggcgcgtcc tggggttatc ggcgtcgtgc gcggttaagt
    14341 ctgaattgcc cgccggataa accgctgcaa atgggatttc gcaaagcggg ttccagcgat
    14401 atcgtcaatg tcgaacagtg ccccgttttg gcgccccagc ttgaagcatt gctgccccgc
    14461 atcagggcgt gtctggcgag tttacacggc acccgacatc ttgggcatgt tgagctggta
    14521 caggcgggaa gcggtacgct gatgattctg cgccataccg cgccattaag tgcggcggat
    14581 aaagaaaaac tggaacgctt ttcgcattct gagggattgt ctctgttcct ggcgccgttt
    14641 agcgagatac tggaaacggt atctggcgaa gcgccctggt atgattcgca cggcttacgt
    14701 ttaaccttca gtccgcgaga ctttattcag gttaatgagg cggtaaacca gcaaatggtc
    14761 gcccgcgcgc tggagtggct tgatgtgcgc gccgaggatc gtgtcctgga tctgttctgc
    14821 ggaatgggga attttacgct accgctggca acgcgcgcgg caagcgtggt aggggttgag
    14881 ggcgttcagg cgctggtaga aaaaggccgt gaaaacgcca tccgcaatgg tttacataat
    14941 gtgacattct tccacgagaa cctggaggaa gatgtcacga agcagccgtg ggcgaaaaac
    15001 ggctttgaca aagtcttact cgatcctgcg cgtgcggggg ctacaggagt gatgcgacat
    15061 attataaaat taaaacctat tcgcattgtt tatgtatcct gtaacccggc gacgctggcg
    15121 cgcgatagtg aagcgctggt caatgcggga tatgaggtta cgcgtttagc gatgctcgac
    15181 atgttcccgc acacaggaca tctggaatca atggttctgt tcgagcgcat gtaatgatta
    15241 ccggcttacc gacttcggta ggcctggtcc cttaaggaga ggacgatggt cgcggtaaga
    15301 agtgcacata ttaataaagc tggtgaattt gatccgaaga agtggatcgc aagcctggga
    15361 atttccagcc agcagtcgtg tgagcgctta gccgaaacct gggcgtattg cctgcaacag
    15421 acacaaggac atccggatgc ggatctgttg ctgtggcgtg gcgtggagat ggtagaaatt
    15481 ctttccacgc tgagtatgga tatcgacacg ctgcgggcgg cgctactgtt ccctctggcc
    15541 gacgccaacg tagtcagcga agatgtactg cgcgaaagcg ttggcaaatc tatcgttacc
    15601 ctgattcatg gcgtgcgcga tatggcggcg atccgccagt taaacgccac tcataacgac
    15661 tctgtttctt cggagcaggt tgataacgtc cgtcgaatgt tattggcgat ggtggatgat
    15721 ttccgctgcg tggtcatcaa actggccgag cgaatcgctc atttgcgcga agtgaaagag
    15781 gcgccggaag atgagcgcgt gctggcggcg aaagaatgta ccaacatcta tgcgccgctc
    15841 gctaatcgtc tgggcatcgg gcaactgaag tgggaactgg aagactactg tttccgctac
    15901 ctgcatccgg cggaatacaa acgcatcgcc aaactgctgc atgaacgccg cctcgatcgc
    15961 gaacattaca tcgaagagtt tgttggacat ctgcgcgccg aaatgaaaaa cgaaggcgtg
    16021 caggcggaag tctacggacg accaaaacat atttatagca tctggcgcaa aatgcagaaa
    16081 aagcatctgg cgtttgatga actctttgac gtgcgcgccg tgcgtatcgt cgctgaacgt
    16141 ctgcaagact gctacgccgc gttggggata gtgcatacgc actatcgcca cctgccggat
    16201 gaattcgatg attatgtcgc taacccgaaa ccgaacggtt accagtctat ccacaccgtg
    16261 gtcttggggc cgggcggtaa aaccgttgag atccagatcc gtaccaaaca gatgcatgaa
    16321 gacgccgaac tgggtgtggc ggcgcactgg aagtataaag aaggcgccgc gtccggcggc
    16381 gtgcgttccg gccatgaaga cagaattgcg tggctgcgta agctgatcgc ctggcaggaa
    16441 gagatggccg attccggcga aatgctggat gaagtgcgca gccaggtgtt tgacgatcgg
    16501 gtctacgttt ttacgccaaa aggcgacgtg gttgacttgc ctgccggatc tacgccgctc
    16561 gattttgctt accacatcca cagcgatgtc gggcaccgct gcatcggcgc gaaaattggt
    16621 gggcgcatcg taccgtttac ctaccagtta cagatgggcg atcaggttga aattatcact
    16681 cagaagcagc cgaatcccag ccgcgactgg ctgaatccaa acctgggcta tgtgacgacc
    16741 agccgcggac gctcgaaaat tcacgcctgg ttccgtaaac aggaccgtga caaaaatatc
    16801 ctggctggac ggcagatcct cgacgatgag ctggcgcatt tggggattag cctgaaagag
    16861 gccgaaaaac atctgctgcc gcgctacaac tttaatgagc tggaagagtt gctggcggcg
    16921 ataggcggcg gcgatatccg tcttaatcag atggtgaatt tcctgcaatc gcagttcaat
    16981 aagccgagtg cagaggagca ggatgcagcg gcgctgaaac agcttcagca aaaaacatac
    17041 gcgccgcaaa atcgtcgtaa agacgacggg cgcgtggtgg tggaaggggt tggtaacctg
    17101 atgcaccaca ttgcccgctg ctgccagccg attccggggg atgaaattgt cggcttcatt
    17161 actcaggggc gggggatttc cgtgcaccgg gccgactgcg aacagctggc ggaactgcgc
    17221 tcccatgcgc cggagcggat cgtagaggcg gtatggggcg aaagctactc ggcgggatat
    17281 tcgctggtgg tgcgcgtcca ggccaacgat cgcagcggtt tattgcgtga tatcaccacc
    17341 attctggcta acgaaaaagt caacgtgctg ggcgtcgcca gccgcagcga cattaaacag
    17401 cagatcgcca ccattgatat gaccatcgag atctacaacc tgcaggtgct gggccgcgtg
    17461 ctcggtaagc tgaaccaggt gccggatgtg attgatgcac ggcgactgca cggggggtaa
    17521 accccagaca gtaataatgt agcggctttg ctactcgttc agcaaagccg cattagccaa
    17581 ccccataagc atgatatatg aggtatgttt ttgacgtaca tttcatttca ggtgtactct
    17641 tatgtaagat ttatacttac agtggaggct gttatggcca gaacaatgac cgttgatctt
    17701 ggcgatgaat tgcgcgagtt tattgaatcg ctcatagaat caggtgatta cagaacgcaa
    17761 agtgaagtga tcagagagtc tcttcgtctg ctgagggaaa aacaggccga gtcacgactt
    17821 caggcgttac gtgaacttct ggctgaaggt ctgaacagcg gagagccgca ggcctgggaa
    17881 aaggatgcct ttttacggaa ggtcaaaaca gggatgatca aacccgatga gaacggtaaa
    17941 attaacgcca aaggccagtg aagatctgga aaatatctgg cattacggct ggcagcattt
    18001 tggtgaaata caggccgatc gatatattca tcatctatca gaaatattca gcattatgag
    18061 tgccaataac attggcacgc ctcgacctga actgggtgaa tacatttatg ccttaccgtt
    18121 tgaaaggcat attatctatt ttatataatc agttacggaa gttatcgtga tacgtattct
    18181 gagccagaat caggatgctg gtaagcat
//
LOCUS       DAJVKX010000086        17754 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000086 DAJVKX010000000
VERSION     DAJVKX010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17754
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.086"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            72..521
                     /gene="alaE"
                     /locus_tag="OPY25_003030"
     CDS             72..521
                     /gene="alaE"
                     /locus_tag="OPY25_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HCS0928590.1"
                     /translation="MFSPQSRLRHAVADTFAMVVHCSVVNMLIEIFLSGMSFEQSLSS
                     RLVAIPVNILIAWPYGVYRDLIMRVARKASPAGWAKNLADVLAYVTFQSPVYIIILLT
                     VGAGWHQIVAAVSSNIVVSMLMGAVYGYFLNYCRRLFKVSSYHQAKA"
     gene            complement(556..906)
                     /locus_tag="OPY25_003031"
     CDS             complement(556..906)
                     /locus_tag="OPY25_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HCS0928591.1"
                     /translation="MYLRPDEVARVLEKAGFTVDVVTNKTYGYRRGENYVYVNREARM
                     GRTALIIHPRLKDRSSSLADPASDIKTCDHYQNFPLYLGGETHEHYGIPHGFSSRIAL
                     ERYLNGLFGDEKSD"
     gene            1068..1394
                     /locus_tag="OPY25_003032"
     CDS             1068..1394
                     /locus_tag="OPY25_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HCS0928592.1"
                     /translation="MLNKPNRNDVDDGVQDIQNDVNRLADSLEDVLKSWGSDAKDEAE
                     AARRKAQALLKETRARMQGRTRVKQAACDAMGCADTFVREKPWCSVGTAAAVGIFIGA
                     LLSLRR"
     gene            complement(1478..2812)
                     /locus_tag="OPY25_003033"
                     /pseudo
     CDS             complement(1478..2812)
                     /locus_tag="OPY25_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461729.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
     gene            2901..3332
                     /locus_tag="OPY25_003034"
     CDS             2901..3332
                     /locus_tag="OPY25_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCS0928593.1"
                     /translation="MTTLRQPYYELSPEVYSALVQAKNALEKSTIDPTLMELIYLRVS
                     QINGCAFFLEMHSKALRKAGVNQAKLDALAGWRVSHHFNEQECAALAWAESVTHIAET
                     HAEDNVYLPLLDHFSAREISDLTFAIGLMNCFNRLAIGMRM"
     gene            3604..3849
                     /gene="nrdH"
                     /locus_tag="OPY25_003035"
     CDS             3604..3849
                     /gene="nrdH"
                     /locus_tag="OPY25_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCS0928594.1"
                     /translation="MSITIYTRNNCVQCHATKRAMESRGFEFEMVNVDLVPDAADTLR
                     AQGFRQLPVVMAGDLSWSGFRPDMINRLPPTPHAANA"
     gene            3846..4256
                     /gene="nrdI"
                     /locus_tag="OPY25_003036"
     CDS             3846..4256
                     /gene="nrdI"
                     /locus_tag="OPY25_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCS0928595.1"
                     /translation="MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIQVDEPYIL
                     VVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKCG
                     VPWLYRFELMGTQRDIDNVRKGVNEFWQQSPRSA"
     gene            4229..6373
                     /gene="nrdE"
                     /locus_tag="OPY25_003037"
     CDS             4229..6373
                     /gene="nrdE"
                     /locus_tag="OPY25_003037"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCS0928596.1"
                     /translation="MATITPERVMQETMDYHALNAMLNLYDKAGHIQFDKDQQAIDAF
                     FAAHVRPHSVKFASQHERLETLVREGYYDDAVLARYDRAFVFRLFEHAHASGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEHFEDRVTMVALTLAQGDETLATQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFRLAKENAQMALFSPYDIQRRYGKPFGDIAISERYDEL
                     IADPHVRKTYINARDFFQTLAEIQFESGYLYIMFEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASRYDDNLDYTHIGHDISCNLGSLNIAHVMDSPDIGRTVETAIRGLTAVSDMSH
                     IRSVPSIAAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNFYFYTITWHAVHT
                     SMRLARERGKTFAGFAQSRYASGDYFTQYLQDDWQPKTAKVRALFARSGITLPTREMW
                     LKLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKIEIRKEGKTGRVYYPA
                     PFMTNENLDMYQDAYDIGPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKSLYYIRLRQLALESTEIEGCVSCAL"
     gene            6384..7343
                     /gene="nrdF"
                     /locus_tag="OPY25_003038"
     CDS             6384..7343
                     /gene="nrdF"
                     /locus_tag="OPY25_003038"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCS0928597.1"
                     /translation="MKLSRISAINWNKIQDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLSAAEQQLTIRVFTGLTLLDTIQNIAGAPSLMADAITPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKEVDAAYAWSEENPPLQRKAQIILAHYVSDEPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKHQIALQKLSAIEREEL
                     KLFALDLLMELYDNEICYTEALYAETGWVNDVKAFLCYNANKALMNLGYEALFPPEMA
                     DVNPAILAALSPNADENHDFFSGSGSSYVMGKTVETEDEDWNF"
     gene            7698..8899
                     /gene="proV"
                     /locus_tag="OPY25_003039"
                     /pseudo
     CDS             7698..8899
                     /gene="proV"
                     /locus_tag="OPY25_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
     gene            8892..9956
                     /gene="proW"
                     /locus_tag="OPY25_003040"
     CDS             8892..9956
                     /gene="proW"
                     /locus_tag="OPY25_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HCS0928598.1"
                     /translation="MADQTNPWDTAQVADTTTQTADAWGTPAGVATDGGSTDWLNSAP
                     APAPEHFSLLDPFHKTLIPLDSWVTEGIDWVVTHFRPLFQGIRVPVDYILNGFQQLLL
                     GMPAPVAIILFALIAWQVSGVGMGIAALISLIAIGAIGAWSQAMITLALVLTALLFCV
                     VIGLPMGIWLARSPRAAKIVRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLITRPFVK"
     gene            10026..11021
                     /gene="proX"
                     /locus_tag="OPY25_003041"
     CDS             10026..11021
                     /gene="proX"
                     /locus_tag="OPY25_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HCS0928599.1"
                     /translation="MRHTVIFASAFATLVTASAFAADLPGKGITVQPIQSTISEESFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSIASGDATFTAVNWQPLHDDMYAAAGGDKK
                     FYREGVFVSGAAQGYLIDKKTAEQYNITNIAQLKDPKIAKIFDTNGDGKADMMGCSPG
                     WGCEAVINHQNKAFDLQKTVEVSHGNYAAMMADTITRFKEGKPVLYYTWTPYWVSDVM
                     KPGKDVVWLQVPFSSLPGEQKNIDTKLPNGANYGFPVNTMHIVANKAWAEKNPAAAKL
                     FAIMKLPLADINAQNAMMHAGKSSEADVQGHVDGWINAHQQQFDGWVKEALAAQK"
     gene            11186..12370
                     /locus_tag="OPY25_003042"
     CDS             11186..12370
                     /locus_tag="OPY25_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928600.1"
                     /translation="MTKPTHGLSPALIVLMSVATGLAVASNYYAQPLLDTIAHHFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRTLIVSMTLLAAGGMLITASSQSLSMM
                     ILGTALTGLFSVVAQILVPLAATLATPATRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASALMALMAVALWRGLPKLKSDTHLNYPQLLGSVFSLFIHDKLLRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFSYSEGMIGLFGLAGAAGALGARPAGGFADKGKS
                     HLTTTFGLLLLLLSWLAIWLGRTSVLALIIGILVLDLTVQGVHITNQTVIYRLHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHAGWAGVCLAGVTVALLNLLVWWRGFHRQEA
                     VN"
     gene            12867..13397
                     /gene="mprA"
                     /locus_tag="OPY25_003043"
     CDS             12867..13397
                     /gene="mprA"
                     /locus_tag="OPY25_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor MprA"
                     /protein_id="HCS0928601.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQGKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGQAFLQEVLPPQHHCLHQLWSSLSTAEKDQLEHITRKLLT
                     RLDQMEQEGTVLEALR"
     gene            13524..14696
                     /gene="emrA"
                     /locus_tag="OPY25_003044"
     CDS             13524..14696
                     /gene="emrA"
                     /locus_tag="OPY25_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HCS0928602.1"
                     /translation="MSANAEIQPPQQPAKKKGKRKTALLLLTLLFVIIAVAYGIYWFL
                     VLRHIEETDDAYVAGNQVQIMAQVSGSVTKVWADNTDFVKEGDVLVTLDQTDAKQAFE
                     RAKTALASSVRQTHQLMINSKQLQANIDVQKTALAQAQSDLNRRVPLGNANLIGREEL
                     QHARDAVASAQAQLDVAIQQYNANQAMILNSNLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATDLWVDANFKETQLANMRIGQPVTIIT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRVELDARQLEQHP
                     LRIGLSTLVTVDTANRDGQVLASQVRTTPVAESNAREINLAPVNKLIDDIVQANAG"
     gene            14713..16251
                     /gene="emrB"
                     /locus_tag="OPY25_003045"
     CDS             14713..16251
                     /gene="emrB"
                     /locus_tag="OPY25_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HCS0928603.1"
                     /translation="MQQQKPLEGAQLIIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRFGEVKLFMWSTVAFAAASWACGVSSSL
                     NMLIFFRVVQGVVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGIAVVLMTLHTLRGRETHTERRRIDAVGLALLVIGISSLQI
                     MLDRGKELDWFSSQEIIILTVVAVIAISFLIVWELTDDHPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAWTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTDRESLHHAQLTESVTAYNPNAQAMYDKL
                     EGLGMTHQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(16300..17670)
                     /locus_tag="OPY25_003046"
     CDS             complement(16300..17670)
                     /locus_tag="OPY25_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HCS0928604.1"
                     /translation="MKAKYLALMIGACFSHNLWAANDITIEQRLAELEQRVVNAEKRA
                     SDAEAQIRSLKQQQVAATPTVNVQSAEPIAADKTPPKLTLSGFSDIKFYGDVEFNMDA
                     ASRSGSLTSMRTSANKDWASGTNERWDINGRLLLGFDGYQRLDNGNFAGFSVQPLADL
                     TGKMNLDDAVFFFGRENDWKIKVGRFEAYDMFPLNQDTFIEYSGNTANDLYSDGYGYI
                     YMMKEGRGRSDSGGNFLLSKTIDNWYFEVNTLLENGSTLYTEKQYHGMDLTNDKNVAY
                     VRPVIAWQNGRFSTAIAMESNVVNNAYGYYENGKWIDQSDRTGYGFTMTWNGQKTDPE
                     DGAVINLNTAYMDATDETDFTAGVNALWHRFELGYIYAHNKIEAFNATNIDAVCEDDC
                     WITDPGNYDIHTIHASYLFPNVMDMKNFNIYLGAYASWVEANPNNGDNSEDARYGGRL
                     RFKYFF"
BASE COUNT         4086 a         4782 c         4597 g         4289 t
ORIGIN      
        1 acaaaagcgc tttataattt cactaccaac tatcacctca ttctgatcga tacgctacaa
       61 ggagcattaa catgttctct ccacagtcac gcttgcgtca tgccgtagca gacacgtttg
      121 cgatggttgt tcactgttct gttgtgaaca tgttgatcga gatattcctc tccggaatga
      181 gctttgagca gtcgctttct tccaggctgg tggcgatacc tgtcaacatt ttgattgcat
      241 ggccatacgg cgtttaccgc gatctgatta tgcgcgtcgc gcgtaaggca agcccggcgg
      301 gatgggccaa aaacctggcg gatgtattgg cttatgtcac ctttcagtca cccgtttata
      361 ttatcatctt gctgaccgtc ggcgccggct ggcatcagat agtggccgcc gtgagttcaa
      421 acattgttgt ttcaatgtta atgggcgcgg tttatggcta cttcctgaat tattgtcgtc
      481 gcctgtttaa agtgagcagc tatcatcagg ctaaggcata agttaacgtc gcgactggct
      541 ttgccagtcg cgcttttagt cgcttttttc gtcgccaaaa agcccattca gataacgttc
      601 taacgctatt cgggagctaa agccgtgggg aataccgtaa tgttcgtggg tctcgccgcc
      661 taaatagagc ggaaaatttt ggtagtgatc gcaggtttta atatccgaag ccgggtcagc
      721 cagtgatgag ctacggtctt ttaatctggg gtgaatgatc agcgcggtac gccccatacg
      781 cgcctcgcgg ttaacataaa cataattctc gccgcgtcga taaccatacg tcttattcgt
      841 caccacatcg acggtaaacc ctgccttttc cagtacccgc gccacctcgt caggtcgtaa
      901 atacatgttt tatcctcatt ctcttttact gcgggcttac cttacccgat agcgcgttat
      961 caacgctttc agaaaagtcc agaaacgcat gatatcgccg taacaagcct cagcaggtaa
     1021 aaatatgaac tacactgaaa gctacatcga aatcaatgga ggatcatatg cttaacaaac
     1081 cgaaccgaaa cgacgtcgat gatggtgttc aggatattca gaatgatgtc aatcgattag
     1141 ccgacagtct ggaagatgtc cttaaatcct ggggaagcga tgcgaaagac gaagccgagg
     1201 ctgcgcgacg taaagcacag gcgttgctga aagagacccg ggcgcggatg cagggtcgta
     1261 ctcgcgtaaa acaagccgcc tgtgatgcga tggggtgcgc ggatacgttt gtgcgtgaaa
     1321 aaccctggtg tagcgtagga accgccgcag cggtggggat ttttatcggg gcgctgctta
     1381 gcctgcgtcg ctaacgacgt gcgctgccgg atggcgacat actttatggg gcctgcatca
     1441 ttgccgcagg cccaggtcgc gccattcggc gaaacggtta ctgtatcgcc tgtcgaagct
     1501 gacatgctac ctgtttcgcc atgccagcgg aagtaatatt ggtaaacgac agtaaaatgc
     1561 ccccctttcc tgacgaaacc actcgccaac gacttagcgc ctgtaccgcc agtccggcct
     1621 gattcgcttt tgctaccagc gctttatcat caccttcaac ctcaataacc aattgaatac
     1681 cgcctttctg taatgtcacg acaaatccct gttctgccag cgcctcttca atccataacc
     1741 gtcgctgagc ataatgttga cgcatctttt tcagatgccg ccagaaatgg ccatcacgga
     1801 taaaatcagc cagcgtgtgc tgccataaca acggtacgct acagggcatc agcgacgcct
     1861 gctggcggaa atgctcaatc tgctttatcg gcaccaccag ccaggcggta cgtaatgccg
     1921 gaaagagcga cttactgaac gttccggcgt aaatcactcg ctgcggggca tccagactct
     1981 tgagcggcgg aagcggttta ccgtgataac gaaattcgct gtcgtagtca tcttcaataa
     2041 tccaggcctg cacattcgcc gcccatgcca gaagttgccg tcggcgagtt aacgacagcg
     2101 ccacccccaa cggactttga tgggcgggcg tcaccaatgc aaagcgtccc tgcgggcaat
     2161 cccgcatccc cgctgcgaca ttcagcccat cggcatcgac cggaatcggc gccagcgtaa
     2221 tcccctcctg cgttatcacc gggcgaatta acggaaagcc gggatcttcc acccacatgc
     2281 tgtctcccgg cacagacaat gtacgcagga ttagccgcat agaatccgca tatccggagg
     2341 taataaatac ctgttccggc agacattcaa tgctacgcga aacccgcagg taatcgacta
     2401 tcgcctagcg caaaatcgcc tcgccgcaga cgtcgcctaa tgccagatcg aagcgtgtct
     2461 gcgtgcgcaa ccgacgcccc attactcgcg cccacttctc gcgtggaaag agatccagcg
     2521 ccggtaaccc catctgaaag ggtttcggtt ccggactttc tccggcaaaa acagcgggta
     2581 tcggcggcgc cgtctcaaac cgtagagcgt tgctcacaaa cgtgcctgcc tggccacgtc
     2641 gctccagcca gccctgcgct accagctcgc cataggcatt ttccaccgtg gcgcgagaaa
     2701 cgcccagttc ctgcgcccac gtccgactgg aaggcaaacg cgttccgggc gcgagttctc
     2761 cttgctcaat ggccgttttt aactgacgag cgatgtactg atagcgcggc atatggtctg
     2821 ctttttctgt aaaaatatgg ctctctttta cagaccatta tagtgctaca gtgctcgtca
     2881 tcaacacgag gagaaacata atgacgacgt tacgccaacc ctattatgaa ctgagcccgg
     2941 aggtttacag cgctctggtg caggcgaaaa acgcgctgga aaagagcacg attgacccca
     3001 ctctgatgga gctgatttac ctgcgtgttt cgcaaataaa tggttgtgca tttttcctgg
     3061 agatgcacag taaagcgctg cgtaaggctg gcgtgaatca agctaaatta gatgcgctgg
     3121 caggatggcg ggtaagccac catttcaacg agcaagagtg cgcggcgtta gcctgggcgg
     3181 aatcggtgac gcacattgct gaaacccacg ccgaagataa tgtttacctg ccgctgctcg
     3241 atcatttcag cgcgcgtgaa atcagcgatc tgaccttcgc tattggttta atgaactgct
     3301 ttaaccgtct ggcgatcggt atgcgaatgt gacgcattgt tgccggatag cgctgatgtc
     3361 agccaactct gttatgcgtg aacctgcagg ccggatcggg cgttcacgcc gccatccggc
     3421 aaaaattagc catgccgccc ctaccccgct gcgttcatca gcggcgttaa aatcaatcga
     3481 aaattcccat atcttgtatg gttgaatctt aattcaacta catctagtat ttcgtgtatc
     3541 aacacacgac aatccgacgc gtttcatcgc gccgttttct cattttaaat ggaaatacga
     3601 atcatgagca ttactattta cactcgcaat aactgtgttc agtgccacgc cacaaagcgg
     3661 gcgatggaaa gccgtggatt tgaatttgag atggtgaacg tcgatctggt gccggatgca
     3721 gcggatacgc tccgggcgca agggtttcgt caattaccgg tggtgatggc gggcgatttg
     3781 agctggtctg gcttccgtcc ggacatgatt aaccgtctgc ccccgacgcc ccacgcggca
     3841 aacgcatgag cgcgctcgtc tacttctcca gcagctctga aaatacgcac cgttttatgc
     3901 agcgtctggg gctgcccgcc acgcgtattc cgctcaatga acgggagcga attcaggtag
     3961 acgaaccgta cattctggtt gtgccgtcat acggcggcgg cgggatggcc ggtgcggtgc
     4021 cgcgacaggt gatccgcttt ttaaatgatg aacacaaccg ggcgcgcatt cgcggcgtca
     4081 tcgcctccgg taaccgcaat ttcggcgatg cctggggatg cgctggcgat gtgatagcac
     4141 aaaaatgcgg cgtcccctgg ctgtaccgct ttgagctcat gggcacacaa cgcgacatcg
     4201 ataacgtccg aaaaggagta aatgaatttt ggcaacaatc accccggagc gcgtaatgca
     4261 ggaaaccatg gattaccacg ccctgaacgc gatgctgaat ctttacgata aagcaggcca
     4321 tattcagttc gacaaggacc agcaggcgat cgacgccttc tttgccgccc acgtccgccc
     4381 gcattccgtg aagtttgcca gccagcatga acgtctggag acgctggttc gggaagggta
     4441 ttacgatgac gccgtcctcg cgcgttacga ccgcgccttc gtcttccgcc tgttcgagca
     4501 cgcccacgcc agcggctttc gcttccagac gtttcttggc gcctggaagt tctataccag
     4561 ttacacgctg aaaaccttcg acggcaaacg ttatctggaa cactttgaag atcgggtgac
     4621 aatggtggcg ttgacgctgg cgcagggtga cgaaacgctg gccacccaac tgaccgatga
     4681 aatgctttct ggtcgctttc agcccgctac cccgactttt ttaaattgcg gtaaacagca
     4741 gcgtggggaa ctggtctcct gcttcctgct ccgtatcgaa gacaatatgg aatcgatcgg
     4801 gcgagcggtg aattcggcgc tgcaactctc caaacgcggc ggcggcgtcg catttttact
     4861 ctccaatctg cgcgaggcgg gcgcgccgat caaacgcatt gagaatcagt cttccggcgt
     4921 gatcccggtg atgaaaatgc tggaagacgc gttttcgtat gccaaccagc ttggcgcgcg
     4981 ccaaggggcc ggcgcggttt atctccatgc gcaccatccg gatattctgc gttttctgga
     5041 taccaaacgg gaaaatgccg acgaaaaaat ccggatcaaa acgctctctc tcggcgtggt
     5101 gatcccggac atcaccttcc ggctggcgaa agaaaacgcg caaatggcgc tcttttcgcc
     5161 ctatgacata caacgacgct acggcaaacc gtttggcgat atcgccatta gcgaacggta
     5221 cgatgaatta attgccgatc cgcacgtgcg caaaacctat attaacgccc gtgacttttt
     5281 tcaaacactg gcggaaattc agttcgaatc cgggtatctc tacatcatgt ttgaagatac
     5341 ggtaaaccgc gcgaatccta ttgctggtcg cattaatatg agcaacctgt gctcggaaat
     5401 tttacaggtc aatagcgcct ctcgttacga cgataacctt gactataccc acatcgggca
     5461 tgacatctcc tgcaatctcg gctcgctgaa tatcgctcac gtcatggatt caccggacat
     5521 tggccgtacc gtagaaaccg ctattcgcgg cctgacggcg gtgtcggaca tgagccatat
     5581 acgcagcgtg ccctcaatag ccgccggtaa tgccgcctct catgccatcg gtctgggcca
     5641 gatgaatctg catggctatc tggcgaggga aggtattgcc tacggttcgc cggaggcgtt
     5701 ggatttcacc aatttctatt tttacaccat tacctggcat gccgtgcata cttcaatgcg
     5761 gctggcccgc gaacgcggca aaaccttcgc cggatttgcg cagtcgcgct atgccagcgg
     5821 cgactatttt acgcagtatt tacaggacga ctggcaaccg aaaacggcga aagtcagggc
     5881 gctatttgcc cgcagcggca ttacgctgcc cacacgcgaa atgtggctaa agctgcgcga
     5941 cgatgtgatg cgctatggca tctataacca aaatttgcag gcggtgccgc cgaccggttc
     6001 gatttcttac attaatcatg cgacctccag cattcatccg attgtggcca aaattgagat
     6061 tcgcaaagag ggcaaaaccg ggcgtgtgta ttaccccgcg ccgtttatga ctaatgaaaa
     6121 cctggacatg tatcaggatg cttacgatat cggtccggaa aaaattattg atacctatgc
     6181 cgaggccacg cgccacgtcg atcaaggact gtcgctcacc ctgtttttcc ccgataccgc
     6241 cacgacccgc gatatcaaca aagcgcagat ctatgcctgg cgaaaaggta ttaagtcact
     6301 gtattacatc cgacttcgcc agttggcgct ggaaagtact gaaattgaag gctgcgtatc
     6361 ctgcgcgcta taaggaaagc catatgaaat tatctcgtat tagcgccatc aactggaaca
     6421 agatccagga cgacaaagat ctggaggtgt ggaaccggct gaccagtaac ttctggctgc
     6481 cggaaaaagt gccgttatcg aatgatattc cggcctggca gacgctgagc gccgccgaac
     6541 agcagctcac cattcgcgtg tttacgggtc ttacgctgct cgacactatc cagaacatcg
     6601 caggcgcgcc gtcgttaatg gcagatgcca tcacgccgca tgaagaggcc gtactgtcga
     6661 acatcagctt tatggaagcg gtacacgccc gctcttacag ttctattttc tccacgctgt
     6721 gccagacgaa agaggttgat gccgcctacg cctggagcga agaaaaccca ccgcttcagc
     6781 gtaaggcgca gattatttta gctcattacg tcagcgatga accgctaaag aaaaagattg
     6841 ccagcgtctt tttagagtct tttctgttct attccggctt ctggttgccg atgtatttct
     6901 ccagccgcgg taagctcacg aacactgccg acctgattcg tttaatcatt cgcgatgaag
     6961 cggttcacgg ttattatatt ggctataagc atcagatagc gctacaaaaa ctatcggcaa
     7021 tcgagcgtga agagttaaag cttttcgcgc tggatttatt gatggaactg tacgacaacg
     7081 aaatctgcta cacagaagcg ttatatgcgg aaaccggctg ggttaacgac gtcaaagcct
     7141 tcttgtgcta caacgccaat aaagccttaa tgaacctggg ttatgaggcg ttatttccgc
     7201 cggagatggc agacgtgaat cccgcaatcc ttgccgcgct ctcgccgaat gccgacgaaa
     7261 accatgattt cttttccggc tcaggttcat cttatgtgat ggggaaaacg gtcgaaaccg
     7321 aagacgaaga ctggaatttt taaccttgcg ggcatgggaa ataacgttac attttccatg
     7381 cctttatttc aagcaatacc gggttaaatc gcgcaaatat tacaacatgt cctacactca
     7441 atacgagtga cattattcac ctggattcct ccaattcagg tggatttttg ctggttgtct
     7501 caaaaaatat ctctccctcc ccattcgcgt tcagccctta tatcatggga aatcacagcc
     7561 gatagcacct cgcaatattc atgccagaag caaattcagg gttgtctcag attctgagta
     7621 tgttagggta gaaaaaggta actatttcta tcaggtaaca tatcgacata agtaaataac
     7681 aggaatcatt ctattgcatg gcaattaaat tagaagtgaa gaatctgtat aaaatatttg
     7741 gagagcatcc gcagcgtgcc ttcaaatata ttgaaaaggg actatcgaaa gagcaaatac
     7801 tggaaaaaac ggggctatcg cttggcgtta aagacgccag tctggccatt gaagaaggcg
     7861 agatatttgt catcatggga ttatccggct cgggtaaatc cacaatggta cgccttctca
     7921 atcgcctgat tgaacccacc cgcgggcagg tactgattga cggtgttgat attgccaaaa
     7981 tatcagacgc tgagcttcgc gaggtgcgca ggaaaaagat tgcgatggtc ttccagtcat
     8041 ttgcgctcat gccgcatatg accgtgctgg ataatacggc attcggtatg gaattagcgg
     8101 gcatcgcggc gcaagagcgt cgcgaaaagc gctggacgcc ttgcgtcagg tggggcttga
     8161 gaattacgct cacgcctatc cggatgaact ttccggtggg atgcgtcagc gtgttgggct
     8221 tgcccgcgcg ctggcaatca accctgatat cttattaatg gatgaagcgt tttccgccct
     8281 cgatccatta attcgtaccg aaatgcagga tgagctggtg aaattacagg cgaaacatca
     8341 gcgcaccatt gtctttattt cccacgatct tgatgaggct atgcgtattg gcgacaggat
     8401 tgccattatg caaaatggcg aggtcgtaca ggttggtacg ccggatgaga tcctgaataa
     8461 tccggcaaat gattatgtcc gcacgttctt ccgtggcgtg gatattagtc aggtctttag
     8521 cgccaaagat attgcccgtc gcagtccggt cggcttaatt cgtaaaacgc caggttttgg
     8581 tccccgttcg gcactgaaat tattacagga tgaagaccgt gaatatggtt acgtcattga
     8641 gcgtggcaat aaattcgtgg gcgtcgtgtc catcgactca ttaaaagcgg cattaagcca
     8701 ggcgcaaggg attgaagcgg cgcttatcga cgacccttta gtcgttgatg cgcaaacccc
     8761 actcagcgag ttgctctctc acgtcggcca ggcgccctgc gcggtgccgg ttgtcgatga
     8821 agaacaccag tatgttggca ttatttcaaa acgtatgttg ctacaggctt tagatcgcga
     8881 ggggggtaac aatggctgat caaacgaatc cgtgggatac cgcacaggtg gccgatacga
     8941 cgacgcaaac ggctgatgcc tggggaacac cggcaggcgt agccacggac ggcggcagta
     9001 ccgactggtt gaacagcgcg cccgcgccag cccctgaaca cttttctctt ctggacccgt
     9061 tccataagac gcttatcccg ctggatagct gggtcacaga gggaatcgac tgggtcgtca
     9121 cccatttccg tccccttttt caggggattc gtgtgccggt ggattacatc cttaacggct
     9181 ttcagcaact gctgctggga atgcccgccc ctgtggcgat tattctcttt gcgctgattg
     9241 cctggcaggt ttccggtgtg ggcatgggga tcgcggcgct gatatcgctg atcgccatcg
     9301 gcgcgatcgg cgcctggtcg caggcgatga ttaccctggc gctggtgctg accgccctgt
     9361 tgttctgcgt cgtgatcgga ttaccgatgg gaatctggct ggcgcgcagc ccgcgcgcgg
     9421 ccaaaatagt tcgtccgctg ctggatgcga tgcagaccac gcccgcgttt gtctatctgg
     9481 tgccgattgt catgttattc ggcatcggta acgtgccggg cgtggtggtg acgattattt
     9541 ttgctctacc gccgattata cgcctgacga tcctgggcat taaccaggtg cctgccgact
     9601 taattgaagc gtcgcgctcg ttcggcgcca gcccgcgcca aatgttgttc aaagtgcaac
     9661 taccgctggc gatgcccacc attatggcag gcgttaatca gacgctgatg ctggctctct
     9721 caatggtcgt catcgcctcg atgattgcgg tcggtgggct tggccagatg gtactacgcg
     9781 gcattggtcg tcttgatatg gggctggcaa ccgtcggcgg cgtcggcatt gtgattctcg
     9841 ccatcattct ggaccgtctg acgcaggccg tcgggcgcga ctcgcgtagc cgcggtaacc
     9901 gtcgctggta taccaccggt cctgttgggc taatcacccg ccctttcgtt aagtaactct
     9961 cctgacgccc ggtgacattg cgcttaccgg gcttacaact ccctaccata attaaaggaa
    10021 caacgatgcg acatactgtg atatttgcct cagcgtttgc cacccttgtc accgccagcg
    10081 ctttcgctgc cgacctgcct ggcaaaggca ttaccgtcca acctatccaa agcacgattt
    10141 ctgaagagtc cttccagacg ttactggtca gccgggcgct ggaaaagttg ggttataccg
    10201 taaataagcc gagtgaagtc gattacaacg taggctatac ctccatcgcc tctggcgatg
    10261 cgacgtttac cgccgtgaac tggcagccgc tgcatgatga tatgtatgcc gcagcaggcg
    10321 gagacaaaaa gttttaccgc gagggcgtct tcgtctccgg cgctgcgcag ggctatctga
    10381 tcgataaaaa aaccgccgag cagtacaaca tcactaatat cgctcaacta aaagatccga
    10441 aaatcgccaa aatcttcgat accaatggcg acggaaaagc ggacatgatg ggctgctcgc
    10501 cgggctgggg ctgcgaagcc gtaatcaatc accagaataa agcgtttgat ctgcaaaaaa
    10561 ccgttgaggt cagccacggt aactatgcgg cgatgatggc tgataccatt acccgtttta
    10621 aagaaggcaa gccggtgctg tattacacct ggaccccgta ctgggtgagc gacgtaatga
    10681 agccgggtaa agatgtcgtc tggctacagg tgccgttctc ctccctgccg ggcgaacaga
    10741 aaaatattga tactaaactg ccgaacggcg cgaactatgg gttcccggtc aatactatgc
    10801 atattgtcgc caataaggca tgggcggaga aaaatccggc ggcggcgaaa ctgttcgcca
    10861 tcatgaagct gccgctggcg gatatcaacg cgcagaacgc catgatgcat gccggtaaat
    10921 cgtctgaagc cgatgttcag ggccacgtag acggctggat caacgcccac cagcagcagt
    10981 ttgacggctg ggtgaaagaa gcgctggccg cgcagaaata atatcgtttt ttatgccgga
    11041 taaggcgcag ttcatgcgcc gctatccggc caacgcaatc tctcctcaaa gcgcacgatt
    11101 catcacgtca ctgttcccct ttattcatca acatccgcta tgattgtttt cccaggaaat
    11161 aattatctaa atcacgatta ccataatgac gaaacccact catgggctta gcccggcgct
    11221 gatcgtttta atgtctgtgg ccacgggtct ggcggtcgcc agcaactact atgcccagcc
    11281 gctgcttgat accatcgcgc atcacttttc gctttccgcc agctccgcag ggtttatcgt
    11341 taccgccgcg cagttgggct atgccgctgg cctgttgttt ctggtgccgc tcggcgacat
    11401 gtttgaacgc cgaacgctga ttgtctccat gacgttgctg gcggctggcg gaatgctgat
    11461 cactgccagc agtcagtcgc ttagcatgat gatactcgga acggccttaa ccggactgtt
    11521 ctccgtggtg gcgcagattc tggttccgct ggccgccacg cttgcgacgc ccgccacccg
    11581 cggtaaagtg gtcggcacca ttatgagcgg cctgttgctg gggatcctgc tggcgcgaac
    11641 ggtcgccgga ctgctggcaa acctcggcgg ttggcgcacc gtattttggg tagcgtcggc
    11701 gctgatggcg ctgatggccg tcgcgttgtg gcgcggactg ccaaagctca aatccgacac
    11761 ccatcttaac tacccgcaac tgttgggttc tgtattcagc ctgtttattc acgataagct
    11821 gctgcgtacc cgcgcgctgc tgggctgtct gacctttgct aatttcagca tcctctggac
    11881 gtcaatggcc tttttgctcg ccgcgccgcc gtttagctat tccgagggga tgattggcct
    11941 gtttggcctg gcgggggccg ccggcgcttt aggcgcgcgt ccggctggcg gatttgccga
    12001 taaaggtaaa tctcacctca ccaccacgtt cggcttactg ctgctgttac tctcctggct
    12061 ggctatctgg cttgggcgca cctcggtact ggcgctgatt attggtattc tggtactgga
    12121 cctcaccgtt cagggggtac atatcaccaa tcagacggtc atctatcgtt tgcatccgga
    12181 tgcgcgtaac cggctcaccg ccggctatat gaccagctac tttatcggtg gcgccgcggg
    12241 gtcgctgatt tccgcctccg cctggcaaca tgccggctgg gccggcgttt gtctggcggg
    12301 tgtcacggta gccttactta atttactggt ctggtggcga ggttttcacc gacaggaagc
    12361 cgtaaattaa gcggatagtg agcgtttacc tttgtttaag ctccttaggg tgttaaggag
    12421 ctccccagtc tgttaaggtt atgctattca tttatcatgg ttatttttat accggtgaag
    12481 aataatataa ttctatggaa agccctgcat ccccatctgc tcccaggcca atagcgcccg
    12541 ttcaaggatt cgaaggtcgt tcaccgatag ctattcgtga tattccggtg gcttttgcat
    12601 cgggttgtaa ggccgtttac ccggctttcg cccctcccgc ttatcgttct ctcctgattt
    12661 tttcatgcag gcactcacgc ttttctcgtc attcctggat ttgccgcagg cggcgcttta
    12721 ccgggcccaa tgttcccgct gacgtctcag tctgcgtatc attggttgct ttatagcctg
    12781 aaagaatgat tttgtattaa taatacattt actttatttg tcactgtcgt tactatatcg
    12841 gctgaaatta atgaggtcat gcccaaatgg atagttcgtt tacgcccatt gaacaaatgc
    12901 taaaatttcg cgccagccgt cacgaagact ttccttacca ggaaattctt ttgactcgtc
    12961 tttgtatgca catgcaaggc aagctcctgg aaaaccgcaa taaaatgctg aaggctcaag
    13021 ggattaacga gacgttgttt atggcgttga ttacgctgga gtctcaggaa aaccacagta
    13081 ttcagccgtc tgaattaagc tgcgcgctgg gttcatctcg caccaatgcg acacgcattg
    13141 cagatgagct ggaaaaacgc ggctggattg agcgtcgtga gagcgataac gaccgccgtt
    13201 gcctgcatct gcaattaacg gagaaaggcc aggcattttt gcaagaagtg cttccgcctc
    13261 agcatcattg tctgcatcaa ctctggtcat cacttagcac agccgaaaaa gatcaacttg
    13321 agcacatcac tcgtaaactc ctgacgcgtc ttgatcaaat ggagcaggaa ggcactgttc
    13381 ttgaggcgct gcgctaaagc gccgacccgc tcaaaaatcc agattaataa caggaaagcg
    13441 gacaggccgg cacgcgttac tgctggcctt tctgacaaca ggtcggctca gccgatgtga
    13501 ataataagat cgtggagaac aacatgagcg caaatgcgga gatccaaccc ccgcagcaac
    13561 cggctaagaa gaaaggcaaa cgcaaaacag cgctgctact tcttaccttg ctctttgtta
    13621 ttattgccgt ggcatatgga atttattggt ttttagtatt gcgtcatatt gaagagacag
    13681 atgatgctta cgtggcaggg aaccaggttc aaatcatggc gcaggtgtca ggcagcgtga
    13741 cgaaagtctg ggctgataac accgactttg taaaagaggg cgatgttctg gtcacgctcg
    13801 atcagactga cgccaaacaa gcgtttgaaa gagccaaaac ggcgctggcc tccagcgtgc
    13861 gccagacgca ccagttgatg attaacagta agcagttgca ggcgaatatc gacgtgcaaa
    13921 aaaccgccct ggcgcaagcg cagagcgacc ttaaccgtcg tgtgccgctg ggtaatgcca
    13981 atcttattgg ccgggaagag ctgcaacacg cccgcgatgc cgtcgccagc gcgcaggcac
    14041 agcttgatgt cgccattcaa cagtacaatg ccaaccaggc aatgatactt aacagtaatc
    14101 tggaagatca gcctgcggtt caacaagcgg cgaccgaagt gcgtaacgcc tggctggcgc
    14161 tggagcgtac tcgcatcgtc agtccaatga ccggttatgt ctcccgccgc gccgtccagc
    14221 ctggcgcgca gatcagcccc accacgccgc tgatggccgt ggtgcctgca accgatctgt
    14281 gggtggacgc taactttaaa gagacccaat tagcgaatat gcgcattggg cagccagtga
    14341 cgattattac tgacatttat ggcgacgacg taaaatacac cggtaaagtc gtcggtctgg
    14401 atatggggac aggtagcgcc ttctccctgc tgcccgcgca aaatgcgacg ggtaactgga
    14461 ttaaagtggt tcaacgtctg ccggtacgcg tcgaactgga cgcccgccag ttagaacaac
    14521 atccgctgcg cattggttta tcgacgctgg tcaccgtgga taccgctaat cgcgacggtc
    14581 aggtactggc cagccaggta cgaacgacgc cggttgccga aagtaacgca cgcgaaatta
    14641 atctcgcgcc ggtcaataaa ctgatcgacg acatcgtaca ggctaacgcg ggttaatcct
    14701 gaggtgcgtg tgatgcaaca gcaaaaaccg ctggaaggcg cgcagctcat catcatgacg
    14761 atcgcgctgt cgctggcgac attcatgcag gtgctggact ccaccattgc caacgtggcg
    14821 attccgacca tcgccgggaa cctgggttct tccctaagcc aggggacatg ggttatcacc
    14881 tctttcgggg tggcgaacgc tatctcgatt cccttaaccg gctggctggc gaagcgtttt
    14941 ggcgaagtca aactgttcat gtggtcgacg gtcgcctttg ccgcggcctc ctgggcctgt
    15001 ggcgtatcca gcagcctgaa catgctgatc ttcttccgcg tggtgcaggg cgtggtcgcc
    15061 gggccgctga ttccgctctc gcaaagcctg ttgctgaata actatccgcc tgcaaagcgc
    15121 tccattgcgc tggcgctctg gtcaatgacc gtcattgtcg cgccgatttg cggcccgatt
    15181 ctggggggct acatcagtga taattaccac tggggatgga ttttcttcat caacgtgccg
    15241 attggcatcg ccgtcgtcct gatgacgtta cacacgctgc gcggacgtga aactcatacc
    15301 gaacggcgac gtattgacgc cgtcgggctg gcgttactgg tgattggcat cagcagcctg
    15361 caaattatgc tcgaccgcgg taaagagctg gactggttct cctcgcagga aattatcatc
    15421 ctgaccgtgg tcgccgtcat cgccatcagt ttcctgatcg tctgggaact gaccgacgat
    15481 caccctatcg tcgatctttc tctttttaaa tcgcgtaact tcactattgg ctgcctgtgc
    15541 atcagccttg cctatatgct ctatttcggc gccattgttc tattgccgca gcttttgcaa
    15601 gaggtgtacg gctataccgc aacgtgggca ggtctggcgt cggcgccagt cggtattatt
    15661 ccggtaattt tgtcgccgat tatcggacgc ttcgcgcata aactggatat gcgcaggctg
    15721 gtcacattca gcttcattat gtacgccgtc tgtttttact ggcgcgcctg gacgttcgaa
    15781 ccgggtatgg atttcggcgc ttccgcatgg ccgcagttta ttcaaggatt tgccgtcgcc
    15841 tgcttcttta tgccgctgac caccattacg ctctccgggt taccgcccga acggctggcg
    15901 gcggcatcaa gcctgtcgaa cttcacgcga acgctggcgg gctccattgg cacctcgatt
    15961 accaccacta tgtggaccga tcgtgagtcg ctacaccatg cgcagctcac cgagtcggtt
    16021 acggcgtata atccaaacgc tcaggctatg tacgataaac tggaaggctt agggatgacg
    16081 caccaacagg cgtcaggctg gatagcccag caaatcacga atcaggggct gattatttcc
    16141 gccaacgaaa tcttctggat gtcggcgggg atcttcctgg tgctgctcgg cctggtgtgg
    16201 ttcgccaaac cgcccttcgg tgcgggcggc ggcggcggtg gcgcgcacta actatctgat
    16261 aaaagggatc tacggatccc ttttttagta gaccaacaat cagaagaaat atttgaatct
    16321 cagacgcccg ccgtaacgcg catcttcact gttatcgcca ttattcggat tggcctctac
    16381 ccatgaagca taggcgccga ggtagatgtt aaagtttttc atatccatca cgttggggaa
    16441 taaatatgag gcatgaatag tgtggatgtc ataattgccg ggatcggtga tccagcaatc
    16501 gtcctcacaa acggcatcga tattggtagc attaaaggct tcgattttgt tatgcgcata
    16561 gatataaccc agttcaaatc gatgccacag cgcattcacc ccagcggtaa aatctgtctc
    16621 atcggtcgca tccatataag cggtattcag gttaataact gcgccatctt ccgggtcagt
    16681 tttttgacca ttccaggtca tggtaaaacc atagcccgta cgatctgact gatcgatcca
    16741 cttcccattc tcataatagc cataggcgtt gttaacgacg ttactttcca tcgctatcgc
    16801 cgttgaaaaa cgcccgtttt gccaggcaat aaccggacgg acgtaagcca cgtttttatc
    16861 gttggttaaa tccattccgt ggtactgctt ctcggtatat aacgtactgc cattttccag
    16921 caatgtgtta acttcgaaat accagttgtc gatggttttg ctcagcagga agttaccccc
    16981 actgtcgcta cgtccccgtc cttctttcat catatagata tagccgtaac cgtcactgta
    17041 aagatcgttc gctgtattcc ccgaatattc aataaatgta tcctgattca gcgggaacat
    17101 atcgtaggct tcaaaacgac caaccttaat tttccagtca ttctcacgac caaagaagaa
    17161 aacggcatca tcaaggttca ttttcccggt cagatccgcc agaggctgta cagagaatcc
    17221 ggcaaaatta ccgttgtcca gccgctggta gccatcaaag cccagcaaca ggcgcccgtt
    17281 aatatcccag cgttcattgg ttcctgatgc ccaatcttta ttcgctgacg ttctcatcga
    17341 ggtcaggcta ccggaacggc ttgccgcatc catattaaat tcgacatcgc catagaactt
    17401 aatatcgctg aatccggata aggtcagctt cggcggcgtt ttatctgctg caatgggctc
    17461 ggcggactgg acattcaccg tcggtgtagc ggcgacctgc tgctgtttca gcgagcgaat
    17521 ttgcgcctcg gcatcggatg cccgtttttc agcattaaca acacgttgct ccagttcagc
    17581 cagacgctgc tcaatagtga tatcattcgc tgcccaaagg ttatgagaaa agcaagcacc
    17641 gatcatcagc gccaaatatt tagccttcat tttttatccc ttaagtttga tgtataccag
    17701 ataagatttg ctaaaaaccc catcgaccgg ctattagtag agtcttgtta ttac
//
LOCUS       DAJVKX010000087        17542 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000087 DAJVKX010000000
VERSION     DAJVKX010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17542
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.087"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..379
                     /locus_tag="OPY25_003047"
     CDS             <1..379
                     /locus_tag="OPY25_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4751 family protein"
                     /protein_id="HCS0928605.1"
                     /translation="YLFVNTQRANPSIKTVSRFFEYKTWTEQIWRTEIIENGNAFFHW
                     QGHDRKDGHRDTIINYLLNGQRWQSTIEDYIFFHALEGKAWQGHYDNIIEYVSSDHYV
                     YQSAFAEYITDQIHQRAPHGTRF"
     gene            complement(385..1080)
                     /gene="araD"
                     /locus_tag="OPY25_003048"
     CDS             complement(385..1080)
                     /gene="araD"
                     /locus_tag="OPY25_003048"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCS0928606.1"
                     /translation="MLEDLKHQVLEANLALPKHNLVTLTWGNVSAVDRERGVLVIKPS
                     GVDYSVMTADDMVVVSLETGEVVEGHKKPSSDTPTHRLLYQAFPTIGSIVHTHSRHAT
                     IWAQAGQPIPATGTTHADYFYGTIPCTRKMTEAEINGEYEWETGNVIVEAFEKQGINA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQSLLDKH
                     YLRKHGAKAYYGQ"
     gene            complement(1221..2723)
                     /gene="araA"
                     /locus_tag="OPY25_003049"
     CDS             complement(1221..2723)
                     /gene="araA"
                     /locus_tag="OPY25_003049"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCS0928607.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTSPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKEAHTRI
                     GAWMRQAVSKQDTRQLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSIGDGDISALIDEYESSYTLTPATQIHGDKRQNVREAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTDHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKEDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALDLNDMRQFAEIHDIEIAVIDNDTRLPAFKDALRWNEVYYGLKR"
     gene            complement(2734..4443)
                     /gene="araB"
                     /locus_tag="OPY25_003050"
     CDS             complement(2734..4443)
                     /gene="araB"
                     /locus_tag="OPY25_003050"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HCS0928608.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGDEIATSVEWYLRWQEGRYCD
                     GPNNQFRHHPRDYMESMEAALKAVLAQLSAAQRANVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEADEITRLCHKPGKVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQAAVSWIELCDWVPALLSGTTRPQDIRRGRCSAGHKTLWHESWGGLP
                     PASFFDELDPCINRHLRYPLFSETFTADLPVGTLCAEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNTLVKVIGTSTCDILIADKQSVGDRAVKGICGQVDGSVVPNFIGLEAG
                     QSAFGDIYAWFSRVLSWPLEQLAAQHPELKTQINASQKQLLPALTDAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLVASTAFGARAIQECFTEQGI
                     AVNNVMALGGIARKNQVIMQVCCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     AAQQSMASAVERTLRPRPEQAQRFERLYRRYQQWALSAEQHYLPTAAPAPTTPANQAI
                     LTH"
     gene            4784..5629
                     /gene="araC"
                     /locus_tag="OPY25_003051"
     CDS             4784..5629
                     /gene="araC"
                     /locus_tag="OPY25_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HCS0928609.1"
                     /translation="MAETQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGEGVINNNGEQFVCRPGDILLFPPGEIHHYGRHPDASGWYHQWVYFRPRA
                     YWQEWLTWPTIFAQTGFFRPDEARQPHFSELFGQIISAGQGEGRYSELLAINLLEQLL
                     LRRMAVINESLHPPMDSRVRDACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RARCE"
     gene            5748..6515
                     /locus_tag="OPY25_003052"
     CDS             5748..6515
                     /locus_tag="OPY25_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCS0928610.1"
                     /translation="MQALLEHFITQSTLYSLIAVLLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELNFWHTWLVGIIGCLMGDWISFWLGWRFKKPLHRWSFMKKNKSLLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFIGPNLIGCLLWPPFYFLPGI
                     LAGAAIDIPSDMQSGDFKWLLLATALLLWVGGWLCWRLWRSGKAAVDRLTAYLPRSRL
                     LYLAPLTLGIGVVALVVLVRHPLMPVYIDILRKVVGY"
     gene            complement(6554..7261)
                     /gene="thiQ"
                     /locus_tag="OPY25_003053"
     CDS             complement(6554..7261)
                     /gene="thiQ"
                     /locus_tag="OPY25_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HCS0928611.1"
                     /translation="MLKLIDITWLYHHLPMRFTLAVERGEQVAILGPSGAGKSTLLNL
                     IAGFLAPASGTLLIAGEDHTLTPPSRRPVSMLFQENNLFSHLNVQQNIGLGLNPGLTL
                     NASQREKRDAIARQMGIESLMARLPGELSGGQRQRVALARCLVREQPVLLLDEPFSAL
                     DPALRQEMLTLVSDICRERQLTLLMVSHSVEDAARIAPRSIVVADGRIAWQGKTDELL
                     SGQASASALLGIKSHIL"
     gene            complement(7245..8855)
                     /gene="thiP"
                     /locus_tag="OPY25_003054"
     CDS             complement(7245..8855)
                     /gene="thiP"
                     /locus_tag="OPY25_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HCS0928612.1"
                     /translation="MATRRQPLIPGWLIPGLCAAALMITVSLAAFLALWLNAPSGAWS
                     TLWRDSYLWHVVRFSFWQAFLSAVLSVVPAVFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLWQMLGLQWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     SLESIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIFQALSYDYDPARAAMLALIQMVCCLALVLLSQRLSKAIAPGMTLTQ
                     GWRDPDDRLHSRLTDALLIVLALLLLLPPLVAVVVDGVNRSLPEVLAQPILWQAVWTS
                     LRIALAAGVLCVVLTMMLLWSSRELHQRQQLFAGQTLELSGMLILAMPGIVLATGFFL
                     LLNNSVGLPESADGIVIFTNALMAIPYALKVLENPMRDITARYGMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDNFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFTLFTLIEKLPGRHAKTD"
     gene            complement(8831..9814)
                     /locus_tag="OPY25_003055"
     CDS             complement(8831..9814)
                     /locus_tag="OPY25_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HCS0928613.1"
                     /translation="MLKKYLPLLLLCAAPAFAKPVLTVYTYDSFAADWGPGPAVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLEAATQTKLFAKSGVA
                     NEAVKVPGGWKNDTFVPFDYGYFAFVYDKSKLKNPPKSLKELVESDQKWRVIYQDPRT
                     STPGLGLLLWMRKVYGDNAPQAWQKLAAKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHIIEEKKDNYAAANFSEGHYLQVEVAARTVASKQPELAEKFLKFMVSPAFQNAIP
                     TGNWMYPVADVALPAGFESLAKPATTLEFTPQQVAAQRQAWISEWQRAVSR"
     regulatory      complement(9846..9945)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(9992..11650)
                     /gene="sgrR"
                     /locus_tag="OPY25_003056"
     CDS             complement(9992..11650)
                     /gene="sgrR"
                     /locus_tag="OPY25_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SgrR"
                     /protein_id="HCS0928614.1"
                     /translation="MPSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLL
                     NTMQARGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKSA
                     VRQMLISHLGRSFRQGRHILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEE
                     NGELEADIAHHWQQISPLLWRFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHIT
                     KIDSPTAWTLDIHLSQPDRWLPWLLGQVPAMILPREWETLANFASHPIGTGPYAVRRN
                     TPNQLKILAFDDYFGYRALIDEVNVWVLPDISEEPACGLMLEGPIQGGEKAIESRLEE
                     GCYYLLFDARTPRGAHPQVREWVSHVLSPTNLLYHADEPLQQLWFPAYGLLPRWHHAR
                     PGPGEKPAGLETLTLTFYREHIEHRVIARIMSALLAEHQVHLHIQEIDYDQWHAGEIE
                     SDIWLNSANFTLPLDFSLFAHLCEVPLLQNCIPRDWQDDAAQWRAGEMNLANWCQQLL
                     ANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     gene            11743..11865
                     /gene="sgrT"
                     /locus_tag="OPY25_003057"
     CDS             11743..11865
                     /gene="sgrT"
                     /locus_tag="OPY25_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HCS0928615.1"
                     /translation="MRQFWLRYFAATEKTSWLACLSAPQRLKMLAELMQWEATD"
     gene            complement(12200..12805)
                     /gene="leuD"
                     /locus_tag="OPY25_003058"
     CDS             complement(12200..12805)
                     /gene="leuD"
                     /locus_tag="OPY25_003058"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HCS0928616.1"
                     /translation="MAEKFTQHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPEFVLNFPEYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDEQVDELFTLVKANPGIKFEVDLEAQVVKAGDKTY
                     SFKIDDFRRHCMLNGLDSIGLTLQHEDAIAEYENKQPAFMR"
     gene            complement(12816..14216)
                     /gene="leuC"
                     /locus_tag="OPY25_003059"
     CDS             complement(12816..14216)
                     /gene="leuC"
                     /locus_tag="OPY25_003059"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HCS0928617.1"
                     /translation="MAKTLYEKLFDAHVVFEAPNETPLLYIDRHLVHEVTSPQAFDGL
                     RAHHRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCNEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVTGNAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGRDFDEAVEYWKTLKTDDGATFDTV
                     VTLRAEEIAPQVTWGTNPGQVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPL
                     TDVAIDKVFIGSCTNSRIEDLRAAAEVAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRSIK"
     gene            complement(14219..15310)
                     /gene="leuB"
                     /locus_tag="OPY25_003060"
     CDS             complement(14219..15310)
                     /gene="leuB"
                     /locus_tag="OPY25_003060"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HCS0928618.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYD
                     VGGIAIDNHGHPLPKATVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVAKAYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQE
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADEAATAIEQAINRALEEGV
                     RTSDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            complement(15310..16881)
                     /gene="leuA"
                     /locus_tag="OPY25_003061"
     CDS             complement(15310..16881)
                     /gene="leuA"
                     /locus_tag="OPY25_003061"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HCS0928619.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAIN
                     AGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIINVHTNINHHEIWRTSQTVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMEEMGYKDTDYNMGHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFR
                     LDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYD
                     LNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQNKENNKETV"
     gene            complement(16969..17055)
                     /gene="leuL"
                     /locus_tag="OPY25_003062"
     CDS             complement(16969..17055)
                     /gene="leuL"
                     /locus_tag="OPY25_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HCS0928620.1"
                     /translation="MSYIVRFTGLLLLNAFIVRGRPVGGIQH"
BASE COUNT         3779 a         4802 c         4911 g         4050 t
ORIGIN      
        1 ttatcttttc gtcaatactc aacgcgctaa cccttccata aaaaccgtga gtcgattttt
       61 tgagtataaa acatggacag aacagatttg gcgtaccgag attattgaaa acggcaatgc
      121 tttttttcac tggcaaggac acgacagaaa agacggacat cgggatacca ttattaatta
      181 tctgttaaat gggcaacgct ggcagtcaac aatcgaagat tatattttct tccatgcgct
      241 ggaaggaaaa gcgtggcagg gacattatga taatattatt gaatatgtga gttctgatca
      301 ttacgtctat caaagcgcat ttgctgaata tatcaccgac cagattcatc aacgcgcccc
      361 ccatgggacg cgtttttaga ggcattactg cccgtaatag gcttttgcgc cgtgtttgcg
      421 taaatagtgt ttatccagca gggattgctg catgtcgggc aactgcggcg caagctggcg
      481 gcagaagatc cccatatagg ccacttcttc cagcacgatg gcgttatgca cggcatcctc
      541 ggcattttta ccccaggcaa acgggccgtg cgaatggaca agcacgccgg gcatttgagc
      601 ggcgttaatg ccttgttttt caaaggcttc aacaatgaca ttgcccgttt cccattcata
      661 ctcgccatta atttccgcct cggtcatttt gcgagtgcag ggaatcgtac cgtagaaata
      721 gtcggcgtgg gtggtgcccg tcgccggaat cggctgaccc gcctgcgccc agatagtcgc
      781 gtggcgcgaa tgggtgtgta cgatgctgcc gatagtcgga aatgcctgat ataacagacg
      841 gtgggttggc gtatcggacg acggtttctt atgaccttca acgacttcac cggtctccag
      901 gctgaccacc accatatcgt cagcggtcat gacgctataa tcgacgccgg acggcttaat
      961 caccagtacg ccgcgttcgc gatcgacggc gctaacgtta ccccaggtga gggtgaccag
     1021 gttgtgtttt ggcagcgcca gattggcttc cagtacctgg tgtttgagat cttctaacat
     1081 tgttttctcc ctgccggatg gcgcttcgct tatccggcct acgagcgacg gtgtgccgga
     1141 tggcgacata aatgccttat tcggcctaca ggaccgtagg cccggtaaac gcagtgccac
     1201 cgggcattca gacaccactt ttagcgtttt aaaccgtaat acacctcgtt ccagcgcagc
     1261 gcgtccttaa aggctggcag acgggtatcg ttatcaatca ccgcgatttc gatatcgtgt
     1321 atttctgcga actggcgcat atcgttcaga tccagcgcgt ggctgaagac ggtatggtgc
     1381 gcgccgccag ccagaatcca cgcttcggag gcggtcggca gatccggctg cgccttccac
     1441 agcgcgttag ccaccggcag tttcggcagg gagtgcggcg tttttacggt gtcaatgcag
     1501 ttgaccagca ggcggtaacg atcgccgagg tcgatcaggc tggcgacgat cgccgggccg
     1561 gtttgggtat tgaaaatcaa acgcgccgga tcttccttgc cgccaatgcc gaggtgctgg
     1621 acgtcgagga tcggtttctc ttccaccgcg atggagggac acacttccag catgtgcgag
     1681 ccgagcacca gatcgttgcc tttctcgaag tggtcagtgt aatcctccat aaatgaggtg
     1741 ccgccctgca gaccggttga catcactttc ataatgcgaa gcagagcggc ggttttccag
     1801 tcgccttcgc ccgcaaagcc gtagccctgc tgcatcagac gctgtacggc cagacccgga
     1861 agttgtttca gaccgtgtaa atcttcaaaa gtagtagtga atgcgtggaa gccgccctgt
     1921 tccaggaaac gcttcatccc cagttcaatg cgcgccgctt cccgcacgtt ctggcgttta
     1981 tcgccgtgga tctgggtggc gggcgtcagg gtatagctgc tttcatactc gtcaatcaga
     2041 gcgctgatat cgccgtcgcc gatagaattc accacctgca ccagatcgcc gaccgcccag
     2101 gtattgaccg aaaagccaaa tttgatttgc gcggccactt tatcaccgtc agtcactgcg
     2161 acttcacgca tattgtcgcc gaagcggcag acttttagct ggcgggtatc ctgtttagag
     2221 accgcctggc gcatccaggc gccgatacgc gtatgggcct ctttatcctg ccagtggcca
     2281 gtgacgaccg cgtgctgctg gcgcatccgc gcgccgataa aaccgaactc tcggccgcca
     2341 tgcgcagtct ggttcaggtt cataaagtcc atatcgatgc tgtcccacgg cagggcggcg
     2401 ttaaattggg tatggaattg cagtagtggt ttgttaagga tactcagccc gttgatccac
     2461 attttggccg gggagaaggt gtgcagccag accaccagcc ccgcgcagcg atcgtcataa
     2521 ttggcgtcac gacaaatggc ggtaatctca tccggcgagg tgcccagcgg ttttaatacc
     2581 agtttacatg gcagtttggc ttcggtattc agcgcgttga ccacatgctc ggcatgttgg
     2641 gtgacctggc gcagggtttc tgcgccatac aaatgctggc tgccaatcac aaaccatact
     2701 tcataattat caaaaatcgt cattgtcgtg tccttaatga gtcaggattg cctgattggc
     2761 cggggtcgtt ggcgccggcg cggcagtcgg aagataatgt tgttctgcgc ttagcgccca
     2821 ctgctggtag cggcggtaaa gccgttcgaa gcgttgcgcc tgttcagggc ggggacgcag
     2881 agtgcgttct accgcgctcg ccatgctttg ctgggcggca ggaatatcgg catggacttt
     2941 cgcggcaacg gcggcaaaga tagcggcgcc taatgcgcaa cattggtcgg aagcgacgat
     3001 ctgcaacgga cgattcagta cgtcgcagca gacctgcata atgacctgat ttttacgggc
     3061 gatgccgcca agcgccatca cgttattgac cgcgataccc tgctcggtaa aacactcctg
     3121 aatggcgcgc gcgccgaagg cggtcgaggc gaccagaccg ccaaacagcg ctggcgcgtc
     3181 ggtggcgaga ttgagatcgg taatgacgcc tttcagacgc tggttggcat tgggtgtacg
     3241 gcgaccattg aaccagtcga gcaccaccgg caggtgatcc agggacggat ttttcgccca
     3301 ggcgtcggtg agcgctggca atagctgctt ctggctggcg ttaatctggg ttttcagttc
     3361 cgggtgctgc gcggcaagtt gttccagcgg ccagctcaac acgcggctaa accaggcgta
     3421 gatgtcgccg aaagcggact ggcccgcttc cagaccgata aagttcggca ccacgctgcc
     3481 gtcaacctga ccgcaaatgc ctttcacggc gcgatccccg acgctctgtt tatccgcaat
     3541 cagaatgtcg caggttgacg tgccgatgac ttttaccagc gtattgggct gtgcgcccgc
     3601 gccgaccgcg cccatgtgac agtcgaacgc gccgccggaa atcaccacgc tttccggcaa
     3661 gccgaggcgc tgcgcccatt cggcgcacag ggtgcccacg ggcagatcgg cggtgaaggt
     3721 ttcgctaaat aacgggtagc gcagatgacg gttaatgcac ggatcgagtt catcaaagaa
     3781 gctcgcgggc ggcagaccgc cccagctttc atgccacagt gttttgtgcc cagcgctgca
     3841 gcggccacgg cggatatcct gcgggcgagt ggtgccggaa agcagcgccg gcacccagtc
     3901 acacagttca atccacgaga cggcggcctg cgcgacggcg ctatcctggc gggtgacgtg
     3961 cagaatcttc gcccagaacc attcgctgga gtaaatgccg ccaatatagc gggagtagtc
     4021 gaccttacct ggcttatggc acagacgagt gatttcgtcg gcttcttcca cggcggtgtg
     4081 atctttccac agcacaaaca tcgcattcgg gttctcggcg aactccggac gcagcgccag
     4141 gacgttaccg tcggcgtcaa tcggcgctgg cgtagaaccg gtgctgtcaa cgccaatgcc
     4201 aacgacattt gcgcgttgcg cggcgcttaa ttgtgccaga acggctttca gcgcggcctc
     4261 cattgactcc atgtagtcgc gcggatgatg acggaactgg ttgttcgggc cgtcgcaata
     4321 acggccttct tgccagcgca gataccactc tacgctggtg gcgatctcgt cgccggtggc
     4381 gcagtccact gccagagcgc gcactgaatc actgccaaaa tcgaggccaa ttgcaattgc
     4441 catcgtctta ctccatccag aaaaacaggt atggagaaac agtagagagt cgcggcaaaa
     4501 accgtcaggc aggatccgct aatcttatgg acaaaaatgc taatgctttg caaagtgtga
     4561 cgctgtgcaa atattcaatg tggacattcc agccatagtt atagacactt ctgttactta
     4621 attttatcgc ctgaactgta cgcttttgtt acaaagcgct tttcacaagc ggggttgata
     4681 cgtgctttca tcaagcgcaa ggtcttgcgg agacggaagc tctgtcgtcc tggtcaatat
     4741 ggacaatttg tttcttctct gaacatcggg gggtagagaa atcatggctg aaacgcaaaa
     4801 tgatccgcta ttgccgggat attcatttaa tgcccatctg gtcgccgggc tgacgccaat
     4861 tgaagcgaat ggatatctgg atttttttat cgatcgtccg ttgggcatga agggatatat
     4921 tcttaacctg accatccgcg gagagggcgt cattaataat aatggcgagc agtttgtctg
     4981 tcggcctggc gatatattat tgtttccgcc gggcgagatt catcactatg gacggcatcc
     5041 ggatgccagc gggtggtatc accagtgggt ttatttccgg cctcgcgcct actggcagga
     5101 gtggctgacc tggccgacaa tctttgctca gacaggattt ttccgcccgg acgaggcgcg
     5161 ccagccgcat ttcagcgaac tgttcgggca gatcatcagc gccgggcaag gggaaggtcg
     5221 ctattctgag ctactggcga tcaatctgct ggagcagttg ttgctcagac gtatggcggt
     5281 aattaatgag tcgttgcatc cgccgatgga tagccgtgtg cgcgatgcct gccagtatat
     5341 cagcgaccat ctggcagaca gtcattttga tatcgccagc gtcgcccagc atgtctgcct
     5401 gtcgccctcc cggttatcgc atctgttccg ccagcagtta ggcattagcg tattgagctg
     5461 gcgcgaagat cagcgtatca gccaggcgaa actcctgctt agcaccacgc gaatgccgat
     5521 agcgaccgtt gggcgcaatg ttggatttga cgatcagctc tatttttcgc gggtatttaa
     5581 aaaatgcacc ggggcaagtc ctagcgagtt cagggccaga tgtgaataaa aagtgaatga
     5641 tgtgtccaca aagatgtcat aagccgtaac tattcggata attgacggct tgacgaaggg
     5701 ggacggggta agcagaatcc ctgcttcatc acgctgacgg acacactatg caagcactgc
     5761 tggaacactt tatcacccaa tccactctgt attcgctcat cgccgtgttg ctggtcgcct
     5821 tcctggaatc gctggcgctg gtggggttga ttttacccgg cacggtactg atggcggggc
     5881 tgggcgcgct tatcggcagc ggcgagctca atttttggca tacctggctg gtgggtatta
     5941 tcggctgtct gatgggcgac tggatttcgt tctggctggg gtggcgcttt aaaaagccgc
     6001 tacaccgctg gtcttttatg aaaaagaaca agtcgctgct ggataaaacc gaacatgcgc
     6061 tgcatcagca cagtatgttc acgatcctgg tcggacgttt tgtcggtccg acgaggccgc
     6121 tggtgccgat ggtggcaggg atgctggatc ttcccgtagc gaaatttatt gggccaaact
     6181 tgattggctg tttgctgtgg ccgccgtttt atttcctgcc gggcattctg gcgggagcgg
     6241 caatcgatat tccttccgat atgcagagcg gagatttcaa atggctgctg ctggcgacgg
     6301 cgttgctgct gtgggtcgga ggctggctat gctggcggct gtggcgcagc ggcaaagcgg
     6361 cagtcgatcg tttaaccgcg tatctccccc gcagccgttt gctgtatctg gcgccgttga
     6421 cgctcgggat cggcgtggtc gcgctggtgg tgctggttcg ccacccgctg atgccggtgt
     6481 atatcgatat tctgcgcaaa gttgtgggtt actaacgatt cctttgccgg atggcggctt
     6541 cgccttatcc ggcctacaaa atatgggatt tgatgcccaa tagcgctgag gcgctggctt
     6601 gaccgcttag tagctcgtct gttttgcctt gccacgcaat gcgtccgtcg gcgacgacga
     6661 ttgaccgggg cgcaatccgc gccgcatctt ccacgctgtg cgagaccatc aacagcgtga
     6721 gctgtcgctc gcggcagata tcgctgacca acgtcagcat ctcctggcgc agcgcgggat
     6781 cgagcgcgga gaacggttca tccagcagca gcaccggctg ttcacgtacc aggcagcgcg
     6841 ccagcgctac ccgctgacgc tgcccgccgg acagttcgcc cggtaaacgc gccatcagac
     6901 tctcaatgcc catctgacgt gcgatagcgt cccgtttttc ccgctggctg gcgttgagcg
     6961 ttaacccagg gtttagcccc agaccgatat tttgctgcac attcaggtgg ctgaataaat
     7021 tattctcctg aaacagcatt gagaccggac ggcgtgaggg cggcgtaagc gtatggtctt
     7081 cgccggcaat cagtagcgta ccgctggcag gcgcaagaaa accggcaatt aaattcaaca
     7141 acgtgctttt ccccgcgccg ctggggccaa gaatcgccac ctgctcgccg cgttctaccg
     7201 ccagcgtaaa acgcatcggc aaatgatggt aaagccaggt gatatcaatc agttttagca
     7261 tgtcggcccg gtagtttctc tatgagggta aataacgtaa aacagagcag caacagtatc
     7321 agcgcggtca ccgcgccgtc ctggctgcgg taggagccga tctgctgata cagataaaac
     7381 ggcagcgtgc ggaaattgtc attgccgaaa agcgcgacga cgccaaaatc accgatagaa
     7441 agtacgcagg caaacgccag cgcctgcgcc agcggacgtt tcagcgcccg cagttccacg
     7501 acctttaacc gcgaccagcc ttcaattccc aatgactggc acagcattcc ataacgggcg
     7561 gtaatatcgc gcattgggtt ttccaggact tttagcgcgt aggggattgc catcagcgca
     7621 ttggtgaaaa tcacgatgcc gtcggcggat tccggtaagc caacgctgtt attgagcagt
     7681 aaaaagaagc ctgtcgccag cacgatcccc ggcatcgcga ggatcaacat tccgctgagt
     7741 tccagcgttt gtccggcgaa tagttgctgg cgttggtgta gctcgcggct actccacagc
     7801 agcatcatgg tcagcaccac acacagaacg cccgccgcca gcgcaatgcg tagcgatgtc
     7861 cagacagcct gccacagaat gggttgcgcc agcacttccg gcaggctgcg gttgacgcca
     7921 tcgaccacca cggcgaccag cggcggaagc agcaatagta gcgccagcac gattaataag
     7981 gcgtccgtca gacggctgtg gagacgatcg tcaggatcgc gccagccctg cgtcagcgtc
     8041 atccccggcg caatcgcttt gctcaaccgt tgacttagca gtaccagcgc caggcagcag
     8101 accatctgga ttaatgccag catcgccgcg cgggcgggat cgtagtcata actgagcgcc
     8161 tgaaagatag ccagttcgat agtggtggcc tgcgggccgc cgccgagcga caggaccgtt
     8221 gcgaaactgg cgaagcagag cataaaaatc agcgccgcga cgggcggaat ttggcggcgc
     8281 agccacggcc attcgacaaa acggaaaaaa tgccagccgc gcataccgag ctgggcggcg
     8341 agctggcgct gctcgccggg aatgctttcc aacgattgca gcaacaaacg gctcgccatt
     8401 ggcagattaa aaaagacgtg cgccagtaaa atgccctgca agccgtaggg ggagaatgtc
     8461 cactgaagcc ccagcatctg ccacagcgag gccagccagc cctgacgtcc atacacgcta
     8521 agaatgccga acacggcaac cagtaccggc agaatcagcg tcatggcgca cagacgcagc
     8581 agcgccagac gtccaggaaa acggcgtcga taaagcgcgc gggcgagaaa aaccgccggg
     8641 accacagaca gcactgcgga cagaaacgcc tgccagaatg agaagcgcac cacatgccac
     8701 agatagctat cccgccagag tgtcgaccac gcgcccgacg gcgcgttcag ccaaagcgcc
     8761 agaaaggccg ccagcgagac ggttatcatc agcgcggcgg cgcacagccc cggaatcagc
     8821 cagccgggaa ttaacggctg acggcgcgtt gccattcgct aatccatgcc tggcgttgtg
     8881 ctgccacttg ttgcggcgtg aattccagcg ttgtggcggg tttggccaat gattcaaacc
     8941 ctgcgggtaa ggcgacgtcc gctaccgggt acatccagtt gccggtgggt atggcgttct
     9001 gaaacgccgg agaaaccata aatttgagga atttctccgc cagttccggc tgcttactgg
     9061 cgacggtacg cgccgcgact tctacctgta agtaatggcc ttcgctgaag ttcgcggcgg
     9121 cgtaattgtc cttcttctct tcaataatgt gatacgccgg agaggtggtg taactgagca
     9181 ccaaatcgct ttcacctttc agaaataaac cgtaggcctc gctccagcct ttcgtcaccg
     9241 tcaccgtttt ggccgccagt ttttgccagg cctgcggcgc gttatcgcca taaactttgc
     9301 gcatccacag taacagcccc agccctggcg tactggtacg cggatcctga taaatcaccc
     9361 gccatttttg atcgctctcg accagttctt tcaggctttt cggcggattt ttcagcttgc
     9421 ttttatcgta gacaaaggcg aaatagccgt aatcgaacgg cacaaatgtg tcgtttttcc
     9481 agccgccggg caccttgacc gcctcattcg ccacgccgct tttggcaaag agtttagttt
     9541 gcgtggccgc ctccagcaga ttattgtcca gccccaacac cacatcggct ttgctgttct
     9601 tcccctccat ccgcaggcgg ttgagcagcg aaacgccatc ctccagcgcc accagtttca
     9661 gctcgcagtt gcaatcggct tcaaacgctt ttttcaccgc cgggcctggc ccccagtcgg
     9721 cggcgaacga gtcgtaggta tagacggtga gaacgggttt ggcgaaagca ggcgccgcgc
     9781 acaggagtaa aagcggaaga tattttttta acactttgca cctcagttaa agagtggcaa
     9841 aggacttgag aggtagcctc aaatcccttc gccggcatta tccggatcag gttcgacggg
     9901 tattttctca gcgcgcgcat gagcgcggca ccccgttgag ttcggcgtta gtgtagtgat
     9961 tttgttgccg ggcagcaatc aagagctggc gttaaggatc tggcggcgca aaccacgccg
    10021 atttaaaatc aaaccagccg agggtattca tgcgcagccc gcgcatactg cgttgtccct
    10081 ggataatcag ccagtggtgg atcaacggca caatcgcttt gttggccagc agttgctggc
    10141 accagttcgc caggttcatc tcgccagcgc gccactgcgc ggcgtcgtcc tgccagtcgc
    10201 gcggaatgca gttctgcaag agcggtactt cgcacaggtg cgcgaacagc gagaaatcca
    10261 gcggcagcgt aaagttagcg ctattgagcc agatatcgct ttcgatctcg ccggcgtgcc
    10321 attgatcgta gtcgatctcc tgaatatgca gatgcacctg atgttcagcc agaagcgcgc
    10381 tcatgatacg ggcgataacc cggtgctcaa tgtgttcgcg atagaaggtc agcgtgaggg
    10441 tttccagccc ggcgggtttt tcgcccgggc ctggacgggc gtggtgccag cgcggtaaaa
    10501 gcccataggc cgggaaccag agctgctgta gcggttcatc ggcatgatag agtaaattgg
    10561 tgggggagag gacgtggctt acccattctc tgacctgcgg atgcgcgccg cgcggcgttc
    10621 tggcgtcgaa tagcaggtaa tagcacccct cttccagtcg gctttctatc gctttttcac
    10681 cgccttgtat tggcccttcc agcatcaagc cgcaggccgg ttcttcactg atatccggca
    10741 gtacccagac gttcacttcg tctatcaacg cccgatagcc gaagtaatca tcaaaggcga
    10801 gtatcttgag ctggtttggc gtattacgcc gcacggcata aggcccggtg ccgatagggt
    10861 ggctggcgaa attagccagc gtttcccact cccgcggcaa aatcatcgcc gggacctggc
    10921 ccagcagcca cggcaaccag cgatccggct gggaaagatg aatatccagc gtccacgcgg
    10981 taggggagtc tatctttgtg atgtgcgagt aaagcggaag cgtattgata cgcgtcagcg
    11041 aggcgatgac atcttccatc tccagctcgc ggccatgatg aaaatgaatg ccggggcgca
    11101 ggtagaagcg ccacagtaaa ggggaaattt gctgccagtg gtgcgcaatg tccgcttcca
    11161 gttccccgtt ttcctcattt acccgcgtga gcgaactgaa aatttgccgg gcaatatgag
    11221 tttccgagcg acgtaatgcg gttcccggca ggagattgtg catcggacga tagtaaagaa
    11281 cccgcagaat atgccgcccc tggcggaagc tgcgtcccag atgggaaatc agcatttgcc
    11341 tgacagcgct tttatcgccg accagttgta ccagttgatc gattcgatct tgttccagca
    11401 ggtcttccgc ccgctgctgt tgcagcgcca gtccggtata caggaacgtc agacgcgaac
    11461 gctttccgcg tccgacctcg gcttcccatg ttagccaacc gcgcgcctgc atcgtattta
    11521 gcagcgtacg catatggcga cgcgaacagt tcagcagatc cgccagctca ttaagcgtgg
    11581 tgtcttgcgt tttaccgtca caacattgcc agagacggat aaattgttgt tgcaggcgac
    11641 ctgagggcat aaaaggggaa ctccgatgaa aaactcagca attttattat ccctatatta
    11701 ggccaataat atctttcgat gaagcaagag gaagaggtca ctatgcgcca gttctggttg
    11761 agatattttg ccgcgacgga aaaaacgtcc tggctggctt gcctgagcgc gccgcagcgc
    11821 ttaaaaatgc tcgcggaact gatgcagtgg gaggcgaccg attgaagcca attgcagaca
    11881 tcatgtgtga ctgagtattg gtgtaggcga tagcctaaaa tcacccgcca gcagataata
    11941 tctgctggct tttttatttc ggctgtttct ggatgacgac gatgggacgg cgtctcaacg
    12001 ggatttctgc ggcggtttct gtggtcacgc gggtgatgac cgggcgagta aaagacgtat
    12061 aaaaaatgcc ggaatatccc cggcatgagc gactgatgag taaccaggcg cttgatggcg
    12121 ctacgcttat caggcctaca gaatatagtg gcaacctggt gatattgcat accctgtagg
    12181 cccggtaagg cgtgaaaggt taccgcataa atgccggttg tttattttcg tactcggcaa
    12241 tcgcgtcttc gtgctgcagc gtcagcccga tgctgtccag accgttcaac atgcagtggc
    12301 ggcggaagtc gtcgatttta aaactgtagg tcttatcgcc tgctttcacc acctgtgctt
    12361 ccagatccac ttcaaattta atgcccggat tggctttcac cagcgtaaac agctcatcga
    12421 cctgttcgtc gcttaacttc accggcagca gttggttatt gaaactgttg ccgtagaaga
    12481 tgtcggcgaa gcttggcgcg atcaccactt taaaaccgta atcggtcaac gcccacggcg
    12541 cgtgttcgcg tgaagagccg cagccaaagt tttcccgcgc caacagtatc gacgcgcctt
    12601 gatattccgg aaagttcaac acgaattccg gatttggctg ttggcccttt tcgtccagga
    12661 aacgccagtc gttaaacaga tgggcgccaa aaccggtgcg cgtaaccttc tgcaaaaact
    12721 gtttagggat aattgcatcg gtatcgacgt tggcggcatc cagtgggaca accaggccgg
    12781 tatgctgggt aaatttctct gccatggtag tttccttatt tgatgctgcg aatatcggcg
    12841 aagtggccgg taacggcggc agcggcggcc atcgccgggc tgactaaatg cgtgcgaccc
    12901 ccgcggccct gacgaccttc aaagttacgg ttgctggtgg aggcgcagcg ctcgcccggg
    12961 ttcaggcggt cattattcat ggccaggcac atggaacagc ctggtaagcg ccattcaaat
    13021 cctgcttcga taaagatctt gtccagacct tccgcttccg cctgcgcttt caccggacct
    13081 gaacccggca ccaccagcgc ctgcacgcca ggcgcaactt tgcgcccttt ggcgacttcc
    13141 gccgccgcgc gcaaatcttc aatacgcgaa ttggtacaag agccgataaa gactttatca
    13201 atagcaacgt ctgttaacgg tacgcccggc tgtaagccca tataagccag cgctttttcg
    13261 gcgctggcgc gctcaaccgg atcgctaaaa gaggcgggat cggggatgat gtcggtgacg
    13321 gaaatcacct ggcccggatt agtgccccag gtcacctgcg gcgcgatctc ttctgctcgc
    13381 agggtgacga cagtatcaaa ggtcgcgccg tcatcggttt tcagcgtttt ccagtactcg
    13441 acggcttcgt caaaatcgcg gcccttcggc gcgtgcaaac gcccttttac gtagttgaaa
    13501 gtggtttcat ccggggcgac cagaccggct ttggcgccca tctcaatcgc catattgcac
    13561 agcgtcatgc ggccttccat actcagcgcg cggatagcgt cgccgcaaaa ttcaaccacg
    13621 tgtccggtgc cgccggcgct accagtttta ccgatgatcg ccagcacgat gtctttggcg
    13681 gtaatgcccg gtgcggcgtt gcccgtgact tcaatcttca tggttttagc gcgcccctgt
    13741 ttcagggttt gcgtcgccag tacatgttct acctcagaag tgccgatgcc gaaggccaac
    13801 gcgccaaacg cgccgtgggt agcggtgtgg gagtcgccgc agacgatggt catacccggc
    13861 agggtaacgc cctgttccgg ccccatcaca tggacgatgc cctgatatgg gtgattcagg
    13921 tcatacagct cgacgccgaa ctcgttacag ttcttaatca gctcttgcat ctggatacgc
    13981 gccatttcac cagaagcatt aatgtcttta gtctgcgtcg agacgttgtg atccatcgtg
    14041 gcgaaggttt tccccggctg acgtaccgga cgatggtgcg cgcgcagacc gtcaaacgcc
    14101 tgcggcgagg tcacttcgtg taccaggtgg cgatcgatgt acagcagcgg cgtttcgttt
    14161 ggcgcctcaa agaccacgtg ggcatcaaat aatttttcgt ataacgtttt ggccatgatt
    14221 acaccccttc tgcgacatag cgggcgataa tatcgcccat ctcatcggta ctgactgcgg
    14281 cagcgcccct ggctaaatcg ctggtgcgaa ccccctcttc taatgcgcga ttgatcgcct
    14341 gttcaatggc cgttgccgcc tcatcggcat ccaggctgta gcgcagcagc agcgccagcg
    14401 acaggatctg cgcaattggg ttggcgatat ttttcccagc gatatccggc gcggagccgc
    14461 cagccggttc atacaggcca aactcttgct cgttcaggct ggcggagggc aacatcccca
    14521 ttgagccggt gatcatggcg cattcgtcgg acagaatgtc gccgaacagg ttagagcaca
    14581 gcaggacgtc aaactgcgac gggtctttaa tcaactgcat ggtggcgtta tcgatataca
    14641 tgtgcgcgag ttccacatcg ggatacgctt tcgcgacatc attgacgatc tcacgccaca
    14701 ggatagagct ttgcagtacg ttggctttat ctatagaggt gactttacgg cggcgtttac
    14761 gcgccgattc aaaggcgata cgggcaatgc gctcgatctc aaagcggtga taaacttcgg
    14821 tatcaaaggc tttttcgtac tgaccgctgc cttcacggcc ttttggctgt ccgaaataga
    14881 tcccgccggt cagctcgcgc acgcacagga tatcgaaacc gttagcggcg atatcggcgc
    14941 gcaacgggca aaatgcttcc agtccctgat acagtttcgc cggacgcagg ttactgaata
    15001 atttgaaatg tttgcgcagc ggcagcaggg cgccgcgctc cggctggctt tccgggggca
    15061 aattttccca tttcgggccg ccgacggagc caaacagaat ggcatccgcc tgctcacacc
    15121 cttcaacggt ggctttcggc agtggatgac catgattgtc gatagcaata ccgccgacgt
    15181 catagcggct ggtggtgata cgcatatcaa aacggctgcg taccgcatcc ataactttca
    15241 gggcttgcgc catgacttcc gggccgatac cgtcgcccgg cagtacggca atatgatagt
    15301 tcttcgacat tacacggttt ccttgttgtt ctctttattt tgagctttgc gttgcaattc
    15361 tttttcaact tcggcggcgc gccagatatt gttcagtacg tgtaccatcg ctttggcgga
    15421 ggattcgacg atatccgtcg ccagcccgac gccgtggaag cggcgaccat gatggttcac
    15481 gacgatatcg acctgaccca gcgcgtcttt gccctggcct ttggcgttca ggtcgtattt
    15541 aaccaactca acgtcgtagc cagtgatgcg gttaatcgcc tgatagatgg cgtcgaccgg
    15601 gccgttgccg ttcgccgcct cggccttgat ctcttcacca caggccagct tcacggaagc
    15661 ggtggcgata tcgctggagc cggactgcac gctgaagtaa tccagacgga aatgctctgg
    15721 ttcttcttgc tgtttattaa taaacgccag cgcttccagg tcatagtcga acacctggcc
    15781 ttttttgtcc gccagcttca ggaacgcgtc gtacaggtgg cccatgttgt agtctgtgtc
    15841 cttgtaaccc atctcttcca tgcgatgttt cacggcggca cggccagagc gggaggtcag
    15901 gttcagctgt atctggttca gaccgatgga ctctggcgtc atgatttcat agttttcgcg
    15961 gttcttgagg acgccatcct ggtggatgcc ggaagagtgg gcaaaagcgc cgctgccaac
    16021 aatcgctttg ttggccggga tcggcatgtt acagatctgg ctgacggtct ggctggtgcg
    16081 ccagatttcg tggtgattga tgttggtgtg tacgtttatg atgtctttgc gcactttaat
    16141 cgccatgatc acctcttcca gcgcgcagtt accggcacgt tctccgatac cgttcatcgc
    16201 gccttcaact tgacgcgcgc ccgcatgtac tgccgccagc gagttgccta ccgctatccc
    16261 taaatcgtcg tgggtatgaa cggagatgat agctttgtcg atattgggga cacgttcata
    16321 cagaccggaa atgattcccg cgaactcaaa cggcatggta tagcccacgg tatcgggaat
    16381 attgatggtt ctcgcgccgg cgtttatagc ggcttccacc acgcgcgcca gatcgtcaac
    16441 aggcgtccgg ccagcatcct cgcaggagaa ctccacgtca tcagtgtaat tacgcgcccg
    16501 cttaaccatg tataccgcgc gttcgatgac ctcatccagc gtgctgcgca gcttggtggc
    16561 gatgtgcatt ggcgaggtgg cgataaaagt atggatacga aacgcgtcgg cgaccttcag
    16621 cgcctgtgcc gcaacgtcga tgtctttttc tacacaacgc gccagggcgc aaacgcggct
    16681 gtttttgatg gtgcgggcga tggtttggac ggattcaaaa tcacccggag aagagaccgg
    16741 gaagcccact tccatgacat cgacacccat gcgctcaagg gccagggcaa tctgcagctt
    16801 ctctttcgcg ctcaggctgg cctgtaacgc ttgttcgccg tcgcgtaagg tcgtatcaaa
    16861 aataatgact tgctggctca tgatgtggtc cttgtctcca ggggcgcctt gcgtcaggca
    16921 taaaaaaacc cgcacaacgg cgcgggtttt gtttgacttc gagctgactt aatgttgaat
    16981 gccgcccacc ggtctaccgc gcacaataaa tgcgttgagt agtagtagcc cagtgaaacg
    17041 aacgatatat gacattaatt cagctccagc gaatgcgtta tgcttttagt ggtactggat
    17101 atgccgttta atgtcaactc tattttctgt cgccattgca ttttgttgac gatatccgga
    17161 tacgtacttt agctaattgt gctgggctgc gcgtccaata aaggataaaa gaacgagtgg
    17221 acattcatac ttttcattgt ttgaaatatt taggcatttt tgtttgcaaa ttggttaggg
    17281 gaatggcctg ttaaaggtat gctaaaggtt tggtttatct ttttgatttg ttttatattt
    17341 taacaaataa ccttgtttgc ttaatggata aggataaagt tattgataaa ttaatgttaa
    17401 ctttttagct attaataata taaacattta attgaaactt aaatgatcat tcacttggtg
    17461 tatgattgtg tattcgccat agttatggtt atattgcttg cgtaatttaa acattatgaa
    17521 tcgcaatggt gtgactcagg ac
//
LOCUS       DAJVKX010000088        17535 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000088 DAJVKX010000000
VERSION     DAJVKX010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17535
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.088"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            167..232
                     /gene="thrL"
                     /locus_tag="OPY25_003063"
     CDS             167..232
                     /gene="thrL"
                     /locus_tag="OPY25_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HCS0928621.1"
                     /translation="MNRISTTTITTITITTGNGAG"
     misc_feature    168..288
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            314..2776
                     /gene="thrA"
                     /locus_tag="OPY25_003064"
     CDS             314..2776
                     /gene="thrA"
                     /locus_tag="OPY25_003064"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HCS0928622.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNSRQGQVATVLSAPAKIT
                     NHLVAMIEKTIGGQDALPNISDAERIFSDLLAGLASAQPGFPLARLKMVVEQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGLLEARGHRVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASQIPADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASSDDDNLPVKGISNLNNMAMFSVSGPGMKGMIGMAAR
                     VFAAMSRAGISVVLITQSSSEYSISFCVPQSDCARARRAMQDEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQTWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLDNWQAELAQANAPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHQLRFAAAQSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELQKFSGILSGSLSFIFGKLEEGMSLSQATALAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELSDIVIEPVLPDEFDASGDVTAFMAHLPQLDDAFAARVAKARDEG
                     KVLRYVGNIEEDGVCRVKIAEVDGNDLLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     gene            2778..3707
                     /gene="thrB"
                     /locus_tag="OPY25_003065"
     CDS             2778..3707
                     /gene="thrB"
                     /locus_tag="OPY25_003065"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HCS0928623.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGTLLGDVVSVEAADHF
                     RLHNLGRFADKLPPEPRENIVYQCWERFCQALGKTIPVAMTLEKNMPIGSGLGSSACS
                     VVAALVAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENGI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PQLAAALMKDVIAEPYRARLLPGFSQARQAVSEIGALASGISGSGPTLFALCDKPETA
                     QRVADWLSKHYLQNQEGFVHICRLDTAGARVVG"
     gene            3711..4997
                     /gene="thrC"
                     /locus_tag="OPY25_003066"
     CDS             3711..4997
                     /gene="thrC"
                     /locus_tag="OPY25_003066"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HCS0928624.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKQQGLFFPHDLPEFSLTEID
                     EMLNQDFVSRSAKILSAFIGDEIPQQILEERVRAAFAFPAPVAQVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHISGDKPVTILTATSGDTGAAVAHAFYGLENVRVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKTALGLNSANSINISR
                     LLAQICYYFEAVAQLPQGARNQLVISVPSGNFGDLTAGLLAKSLGLPVKRFIAATNIN
                     DTVPRFLHDGKWAPKATQATLSNAMDVSQPNNWPRVEELFRRKIWRLTELGYAAVDDT
                     TTQQTMRELKAKGYISEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVESILGE
                     TLALPEALAERADLPLLSHHLPADFAALRKLMMTRQ"
     gene            complement(5091..5864)
                     /gene="yaaA"
                     /locus_tag="OPY25_003067"
     CDS             complement(5091..5864)
                     /gene="yaaA"
                     /locus_tag="OPY25_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HCS0928625.1"
                     /translation="MLILISPAKTLDYQSPLATTRYTQPELLDHSQQLIQQARQLSAP
                     QISRLMGISDKLADLNATRFHDWQPHFTPDNARQAILAFKGDVYTGLQAETFNDADFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDIITDKLNEALE
                     AQGDRVVVNLASEEYFKSVKPKKLDAELIKPVFLDEKNGKFKVVSFYAKKARGLMSRF
                     IIENRLTKPEQLTAFDREGYFFDEETSTQDELVFKRYEQ"
     gene            complement(5943..7373)
                     /locus_tag="OPY25_003068"
     CDS             complement(5943..7373)
                     /locus_tag="OPY25_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HCS0928626.1"
                     /translation="MPEFFSFINEILWGSVMIYLLLGAGCWFTWRTGFIQFRYIRQFS
                     RSLKGSLSPQPGGLTSFQALCTSLAARIGSGNLAGVALAIAAGGPGAVFWMWVSAIIG
                     MATSFAECSLAQLYKERDPTGQFRGGPAWYMARGLGMRWMGVVFALFLLVAYGLIFNS
                     VQANAVSRALHFAFNIPPLISGIALAFCALLIIIRGIKGVARLMQWLIPLIALLWVAG
                     SVFICLWHIEQMPGVIASIVKSAFGWQEAAAGAAGYTLTQAITSGFQRGMFSNEAGMG
                     STPNAAAAATSYPPHPVAQGIVQMIGVFSDTIIICTASAMIILLAGNHASHSSTEGIQ
                     LLQHAMVSLTGEWGASFVALIVILFAFSSIVANYIYAENNLFFLRLHNAKAIWLLRLA
                     TLGMVIAGTLISFPLIWQLADMIMACMAITNLTAILLLSPVVYTLAGDYLRQRKLGVR
                     PQFDPRRFPDIEPQLAPDTWDAASRD"
     gene            7642..8595
                     /gene="tal"
                     /locus_tag="OPY25_003069"
     CDS             7642..8595
                     /gene="tal"
                     /locus_tag="OPY25_003069"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HCS0928627.1"
                     /translation="MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSSDRAQQVVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRIIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVYLISPFVGRILDWYKANTDKKDYAPAEDPGVVSVTEIYEYYKQHGY
                     ETVVMGASFRNVGEILELAGCDRLTIAPALLKELAESEGAIERKLSFSGEVKARPERI
                     TEAEFLWQHHQDPMAVDKLADGIRKFAVDQEKLEKMIGDLL"
     gene            8706..9296
                     /gene="mog"
                     /locus_tag="OPY25_003070"
     CDS             8706..9296
                     /gene="mog"
                     /locus_tag="OPY25_003070"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HCS0928628.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLASALTTPFELQT
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAIADREMPGFGEQ
                     MRQISLRFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKADDGSVSVPGIFA
                     SVPYCIQLLDGPYVETAPEVVAAFRPKSARRENMSS"
     gene            complement(9353..9919)
                     /gene="satP"
                     /locus_tag="OPY25_003071"
     CDS             complement(9353..9919)
                     /gene="satP"
                     /locus_tag="OPY25_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HCS0928629.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNAGFFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKMGLTDAPDAQLLGAY
                     LGLWGVFTLFMFFGTLKAARALQFVFLSLTVLFALLAVGNITGNEATIHIAGWVGLVC
                     GASAIYLAMGEVLNEQFGRTILPIGEAH"
     gene            complement(10069..10782)
                     /gene="msyB"
                     /locus_tag="OPY25_003072"
     CDS             complement(10069..10782)
                     /gene="msyB"
                     /locus_tag="OPY25_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HCS0928630.1"
                     /translation="MNVTYLHDEDLDFLQHCSEEQLADFARLLTHNEKGKARLSSVLS
                     HNELFKAMEGHPEQHRRNWQLIAGEFQHYGGDSIANKLRGHGKQYRAILLDVAKRLKL
                     KADKSMSTFEIEQQLLEHFLRHTWQKMDAAHKQEFLQAVDAKVSELEELLPLLMKDRS
                     LAKGVSHLLSTQLTRILRTHAAMSILGHGLLRGAGLGGPVGAALNGVKAMSGSAYRVT
                     IPAVLQIACLRRMMAAVQA"
     gene            complement(10818..11222)
                     /locus_tag="OPY25_003073"
     CDS             complement(10818..11222)
                     /locus_tag="OPY25_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HCS0928631.1"
                     /translation="MRSVLTISVGLLFGLALSSVAHANDHKILGVIAMPRNETNDLAL
                     KIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININS
                     DNDNKRCVSKITFSGHTVNSSDMARLKVIGDD"
     gene            11571..13487
                     /gene="dnaK"
                     /locus_tag="OPY25_003074"
     CDS             11571..13487
                     /gene="dnaK"
                     /locus_tag="OPY25_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCS0928632.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIIGADNGDAW
                     LDVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDTRLINYLVDEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     NDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRASD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EEEIQKMVRDAEANAESDRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALSALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQAGSADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            13573..14712
                     /gene="dnaJ"
                     /locus_tag="OPY25_003075"
     CDS             13573..14712
                     /gene="dnaJ"
                     /locus_tag="OPY25_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCS0928633.1"
                     /translation="MAKRDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGFGGGFNGGADFSDIFGDVFG
                     DIFGGGRGRQRAARGADLRYNMDLTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGTQ
                     PQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCHKCHGHGRVEKSKTLSVK
                     IPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAM
                     AALGGEIEVPTLDGRVMLKVPSETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPV
                     GLSEKQKQLLKDLQESFGGPTGEKNSPRSKSFFDGVKKFFDDLTR"
     gene            14997..15944
                     /locus_tag="OPY25_003076"
     CDS             14997..15944
                     /locus_tag="OPY25_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0928634.1"
                     /translation="MGSKGANKSFDYNLIKILDAVILSGNAAMAAKKLGITPAAVSLA
                     LKRLQSYYPEELFSRGKGGLIPTAKAVDIHQNFSQVMKLVDDTFLCNSKKDEAFQITL
                     LGSDIVESYYLSQLYNSDIFDRILINHFSVRNMSREHISELLFTAQGDLLISAEPLLE
                     SGIENQIIDSFKSFVCICSSKHMLSTLSQLSLHHFYSSRHALYQPGMGASVIYHDSEL
                     FKDELYYTGRRIVGYRSDSLNGLMSMIERTSLIALMPLKLALFYKNHRKYDIKFIQPP
                     PELAFKSVQVYASWKKNSRNISTINEMVSMLQTLSSFRR"
     gene            16071..16415
                     /locus_tag="OPY25_003077"
     CDS             16071..16415
                     /locus_tag="OPY25_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCS0928635.1"
                     /translation="MSIPNHVSTTEVVLLELEILLTIISIGAWGGFVSYLLRKDKTEY
                     NSSHESIKYCLTQIVISCFTSFLLSAIAIEKECSFNIVLLAAGLGGVFASPILKILGR
                     RIKKIIGGNNSD"
     gene            complement(16476..17009)
                     /locus_tag="OPY25_003078"
     CDS             complement(16476..17009)
                     /locus_tag="OPY25_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HCS0928636.1"
                     /translation="MNPIIDGIIALEGGYVFNPKDKGGATHWGITEATARAHGYAGDM
                     RDLTHAEAYAILEEDYWIKPGFDVISTLSWPVSFELCDAAVNIGDYHPSAWLQRWLNV
                     FNHEGKRYPDVHVDGNIGPRTLAALEHYLAWRGQEGEAVLVKALNCSQGMYYLNVAEK
                     NHNNEQFIYGWIKNRVT"
     gene            complement(17026..17469)
                     /locus_tag="OPY25_003079"
     CDS             complement(17026..17469)
                     /locus_tag="OPY25_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0928637.1"
                     /translation="MKTYIINSNCIYNEGKYELRTVSNSQVIKMTAMRAKCLSFIIEN
                     AHLEIIERQKITTALWGSRSHYVNDANLTQILYLIRRDLKALGINDLFITIPRQGLKV
                     NSDIAIIATDSETKGRKKQIVRQTIAALTTVFSVTLGSLMYLHIH"
BASE COUNT         4277 a         4331 c         4728 g         4199 t
ORIGIN      
        1 gatcataaca ggggaaattg attgaaaata aatatatcgc cagcagcaca tgaacaagtt
       61 tcggaatgtg atcaatttaa aaatttattg acttaggcgg gcagatactt taaccaatat
      121 aggaatacaa gacagacaaa taaaaatgac agagtacaca acatccatga accgcatcag
      181 caccaccacc attaccacca tcaccattac cacaggtaac ggtgcgggct gacgcgtaca
      241 ggaaacacag aaaaaagccc gcacctgaac agtgcgggct tttttttcga ccagagatca
      301 cgaggtaaca accatgcgag tgttgaagtt cggcggtaca tcagtggcaa atgcagaacg
      361 ttttctgcgt gttgccgata ttctggaaag caattccagg caagggcagg tagcgaccgt
      421 actttccgcc cccgcgaaaa ttaccaacca tctggtggcg atgattgaaa aaactatcgg
      481 cggccaggat gctttgccga atatcagcga tgccgaacgt attttttctg acctgctcgc
      541 aggacttgcc agcgcgcagc cgggattccc gcttgcacgg ttgaaaatgg ttgtcgaaca
      601 agaattcgct cagatcaaac atgttttgca tggtatcagc ctgctgggtc agtgcccgga
      661 tagcatcaac gccgcgctga tttgccgtgg cgaaaaaatg tcgatcgcga ttatggcggg
      721 actcctggag gcgcgtggac atcgcgtcac ggtgatcgat ccggtagaaa aactgctggc
      781 ggtgggccat taccttgaat ctaccgtcga tatcgcggaa tcgactcgcc gtatcgccgc
      841 cagccagatc ccggccgatc acatgatcct gatggcgggc tttactgccg gtaatgaaaa
      901 gggtgaactg gtggtgctgg gccgtaatgg ttccgactat tccgccgccg tgctggccgc
      961 ctgtttacgc gctgactgct gtgaaatctg gactgacgtc gatggcgtgt atacctgtga
     1021 cccgcgccag gtgccggacg ccaggctgtt gaaatcgatg tcctaccagg aagcgatgga
     1081 gctctcttac ttcggcgcta aagtccttca ccctcgcacc ataacgccta tcgcccagtt
     1141 ccagatcccc tgtctgatta aaaataccgg caatccgcag gcgccaggaa cgctgatcgg
     1201 cgcgtccagc gacgatgata atctgccggt taaagggatc tctaacctta acaacatggc
     1261 gatgtttagc gtctccggcc cgggaatgaa agggatgatt gggatggcgg cgcgtgtttt
     1321 cgccgccatg tctcgcgccg ggatctcggt ggtgctcatt acccagtcct cctctgagta
     1381 cagcatcagc ttctgtgtgc cgcagagtga ctgcgcgcgt gcccgccgtg cgatgcagga
     1441 tgagttctat ctggagctga aagaggggct gctggagccg ctggcggtta cggagcggtt
     1501 ggcgattatc tctgttgtcg gcgacggtat gcgcacgcta cgcggcattt cagcgaaatt
     1561 cttcgccgcg ctggcgcggg ctaatatcaa tatcgtggcg atcgctcagg gatcttctga
     1621 gcgttccatt tctgtggtgg tgaataacga cgatgccacc accggcgtgc gggtaacgca
     1681 ccagatgctg ttcaataccg atcaggtgat tgaagtgttt gtcattggcg tcggcggcgt
     1741 cggcggcgcg ctactggaac agcttaaacg tcagcaaacc tggctgaaga acaagcacat
     1801 cgatctacgc gtgtgcggcg tggcgaactc aaaggcgttg ctaaccaatg tgcatggcct
     1861 gaatctggac aactggcagg cggaactggc gcaagcgaac gcgccgttca atctgggacg
     1921 tttaattcgc ctggtgaaag aatatcatct actcaatccg gtgattgttg attgtacctc
     1981 cagtcaggcg gtggccgacc agtatgccga cttcctgcgc gaagggttcc atgtggtgac
     2041 gccgaacaag aaagcgaaca cctcgtcgat ggactactac catcagctac gtttcgccgc
     2101 cgcgcaatca cggcgcaaat tcttgtatga caccaacgtc ggcgccggtt tgccggtaat
     2161 cgaaaacctg caaaacctgc tgaatgcggg tgatgaactg caaaaatttt ccggcattct
     2221 ttccgggtcg ctctctttta ttttcggtaa actggaagag gggatgagtc tctcacaggc
     2281 gaccgctctg gcgcgcgaga tgggctatac cgaacccgat ccgcgcgacg atctttccgg
     2341 tatggatgtg gcgcgtaaac tgttgatcct cgcccgcgag acgggccgcg agctggagct
     2401 ttccgatatc gtgattgaac cggtgttgcc ggacgagttt gacgcctccg gcgatgtgac
     2461 cgcctttatg gcgcatctgc cgcagcttga cgacgcgttt gccgcccgtg tggcgaaagc
     2521 tcgtgatgaa ggtaaggtat tgcgctatgt gggcaatatc gaagaggatg gcgtgtgccg
     2581 cgtgaagatt gccgaagttg atggtaacga tctgctcttc aaagtgaaaa acggtgaaaa
     2641 cgcgctggcg ttctacagcc attattatca gcccttgccg ttggtgctgc gcggctacgg
     2701 cgcaggcaat gatgtgacgg cggcgggcgt gtttgccgat ctgttacgga ccctctcatg
     2761 gaagttagga gtttaacatg gtgaaagtgt atgccccggc ttccagcgcg aacatgagcg
     2821 tcggtttcga cgtgttgggc gcggccgtca cacccgttga cggcacgttg ctgggcgatg
     2881 tggtatccgt tgaagcagcg gatcatttcc gtctgcataa cctggggcga tttgccgata
     2941 aactgccgcc ggagccgcgt gaaaatattg tttatcagtg ctgggaacgt ttttgccagg
     3001 cattggggaa aaccatcccg gtggcgatga cgctggaaaa aaatatgccg attggttccg
     3061 ggttagggtc cagcgcctgt tccgtcgtcg ccgcgctggt cgcgatgaat gagcactgcg
     3121 gcaaaccgtt aaacgacacg cgtctgttgg cgctgatggg cgagctggaa ggccgtatct
     3181 ccggcagcat ccattacgat aacgtcgcgc cgtgctttct tggcggtatg cagttgatga
     3241 ttgaagaaaa cggcattatt agtcagcagg tgccgggctt tgatgagtgg ctatgggtac
     3301 tggcttatcc gggcattaaa gtttccaccg cagaagcacg ggccattttg cctgcgcagt
     3361 atcgccgtca ggattgcatt gcgcatggac ggcatctggc cggttttatt cacgcctgtt
     3421 actcgcggca gccgcagctt gccgccgcgc tgatgaaaga tgttattgcc gaaccatacc
     3481 gcgcgcgttt actgccgggc tttagccagg cgcggcaggc ggtgtcggag atcggcgcgc
     3541 tggcgagcgg gatttccgga tcggggccga cgctgtttgc gctatgcgat aaaccggaga
     3601 cggcgcagcg cgtcgcggac tggctgagca aacattatct gcaaaatcag gaaggcttcg
     3661 ttcatatttg tcggctggat acggcgggcg cacgagtagt gggataatca atgaaactct
     3721 ataatctgaa agaccataat gagcaggtca gctttgcgca ggccgtcacg caagggctgg
     3781 gcaaacagca gggacttttt tttccgcacg atctgccgga gtttagcctg acggaaattg
     3841 atgagatgct caaccaggac tttgtcagcc gtagcgcaaa gatcctctcg gcatttattg
     3901 gcgatgaaat accgcagcaa attctggaag agcgcgtccg cgcggcgttt gctttcccgg
     3961 cgccggtagc gcaggtagaa agtgatgtcg gctgcctgga gctgttccat ggtccgacgc
     4021 tggcctttaa agacttcggc gggcgtttta tggcgcaaat gctgacgcat atcagcggcg
     4081 ataaaccggt gacgattctg accgcaacgt caggcgatac cggcgcggcg gtggctcacg
     4141 cgttctatgg cctggaaaat gtgcgggtcg tcattctcta cccgcgcggt aaaatcagtc
     4201 cgttgcagga aaaactgttc tgtacgctgg gcggcaacat tgagaccgtg gcgatcgacg
     4261 gcgatttcga cgcttgccag gcgctggtga aacaggcatt tgatgacgaa gaactgaaaa
     4321 cggcgctggg gttgaattcg gctaattcga ttaatatcag ccgcctgctg gcgcaaattt
     4381 gctactactt tgaagccgtg gcgcaactgc cgcagggggc gcgtaaccaa ctggtgatct
     4441 ccgtacccag cggcaacttt ggcgatttga cggcaggact gctggcgaag tcgttaggcc
     4501 taccggtgaa acgctttatc gccgccacca acattaacga tacggtgccg cgttttctgc
     4561 atgacgggaa gtgggcgcca aaagcgacgc aggcgaccct gtcgaatgcg atggatgtca
     4621 gccagccgaa taactggccg cgtgtggagg agctattccg ccgtaaaatc tggcgtctga
     4681 ctgagctggg ctatgcggcg gtggatgaca ctacgacaca acagacgatg cgcgagctga
     4741 aagcgaaagg ttatatctcg gaacctcatg cggcggtagc gtatcgggca ttacgcgacc
     4801 agttaaaccc tggcgagtat ggcttgtttc tcggaacggc gcatccggcg aagtttaaag
     4861 aaagcgtgga gtccattctg ggagaaacgc tggcattgcc tgaagcgctc gccgaacgcg
     4921 ccgatctgcc gttgctttca catcatctgc ctgcggattt tgccgccctg cgtaagctaa
     4981 tgatgacccg ccagtaacca ttgcgcccgg tggcgctgtc gcttaccggg cctatggggt
     5041 ggtgccgatt tgtaggccgg ataaggcgta accgccatcc ggcgatgtcg ttactgctcg
     5101 tagcgtttaa agaccagctc gtcttgtgtg gaggtttctt catcaaagaa atacccttca
     5161 cggtcaaacg cggtaagctg ttccggcttc gttaagcggt tttcaataat aaaacgactc
     5221 atcagtccgc gcgctttttt ggcgtagaag cttaccacct taaacttgcc gtttttctca
     5281 tcaaggaata cgggcttaat cagttcggca tccagtttct tcggcttcac cgatttaaaa
     5341 tattcctcgg aggccagatt caccaccacc cgatcgccct gcgcctcaag cgcttcgttg
     5401 agcttatcgg taatgatatc gccccagaat tgataaagat ctttgccgcg cggattctcc
     5461 aggcgaatcc ccatctccag acgataaggc tgcattaaat ccagcgggcg caatacgcca
     5521 tacaagccag agagcatacg cagatgttgt tgagcaaaat caaaatccgc gtcgttgaac
     5581 gtttccgcct gtaggccggt ataaacatcg cctttgaacg ccagaatcgc ctggcgtgca
     5641 ttatccggcg taaaatgagg ctgccagtca tgaaaacgcg tggcgttgag atccgccagt
     5701 ttgtcgctaa ttcccattag cctggaaatt tgcggcgccg aaagctggcg ggcctgttga
     5761 ataagctgct ggctgtgatc caacagctcc ggctgggtat agcgggtcgt ggccagcggg
     5821 ctttgataat caagcgtttt tgcaggtgaa atcagaatca gcatatccag tccttgcagg
     5881 gaattttctg cgactttagc aaaaaaacgc cgcagagttg accgatggtt gcgattgtcg
     5941 gcttaatcgc gcgatgccgc atcccaggta tctggcgcca gttgtggttc gatatccggg
     6001 aagcgccgcg gatcgaactg cggtcttacg cccagtttcc gttgtcgcag ataatcgccg
     6061 gcgagggtat acaccaccgg tgagagcaac aaaatcgccg tcagattggt aatggccata
     6121 caggccatga tcatgtcagc gagctgccat atcagcggaa aactgataag cgtaccggcg
     6181 atgaccatgc caagcgtcgc aagacgtaat agccagatgg cctttgcgtt atgtaaccgc
     6241 agaaaaaaga gattgttttc ggcgtaaata tagttggcga cgatagaact gaacgcgaac
     6301 agaatgacga taagcgcgac aaaactggcg ccccattcac cggtcaacga aaccattgca
     6361 tgttggagaa gctgaatgcc ttctgttgac gaatgggacg cgtgattccc cgccagcagg
     6421 ataatcatcg cgctggcggt acagatgata atggtgtcgc tgaatacgcc aatcatttgc
     6481 acaatcccct gcgcgacagg gtgaggggga tacgacgttg ccgctgcggc cgcattaggc
     6541 gttgacccca ttcccgcttc attagagaac atcccacgct gaaaaccgct ggtaatagcc
     6601 tgggtgagcg tatatccggc tgcgcctgcc gcggcttcct gccagccaaa tgcgcttttg
     6661 actatcgagg cgataacgcc aggcatttgc tcaatatgcc agaggcaaat gaatacgctg
     6721 ccagcgaccc acaataacgc gatgagggga atcagccatt gcatcaggcg ggcgacgcct
     6781 tttatgccgc ggatgataat taacagggca cagaacgcca aagcaatgcc ggagataagc
     6841 ggcggaatgt tgaaggcgaa atggagcgcg cgtgagacgg cattcgcctg cacgctatta
     6901 aaaatcaacc cgtaggcgac gagcagaaag agggcgaaaa ccacgcccat ccagcgcatt
     6961 cccagcccgc gcgccatata ccacgccggg ccgccgcgga actggcctgt cgggtcacgt
     7021 tctttataaa gctgggcaag cgaacactcg gcgaaggagg tcgccatacc aatgatggcc
     7081 gagacccaca tccagaatac tgcgccggga ccgcctgcgg cgatagccag cgccacgccg
     7141 gccagattac cgctgccaat ccgcgccgcg aggctggtac acagcgcctg aaatgacgtc
     7201 aggccgcctg gctgcgggct aaggctgcct ttcagactgc ggctaaattg gcgaatataa
     7261 cgaaactgaa tgaatccggt acgccaggta aaccaacatc ctgcgccgag cagcaggtaa
     7321 atcattaccg agccccagag tatttcgtta ataaaactga aaaactcagg cattaacgtc
     7381 cctcttgttg atgccgacac gctttgatga tcctgtataa gcgtgaccca tgatgtagat
     7441 gaccttgtca ggctaatatt aacggtagtt taccataaat acggcggtat cctttaattg
     7501 cgcatcaacc gtcggcagat acgcaaacag ttcacaaggg cagccaggtg catgtaggcg
     7561 gttgcgctgt gagtgcgtcg tgttatcatc agggtagacc ggttacatcc cctaacaagc
     7621 tgtttaaaga gaaactctat catgacggac aaattgacct cccttcgtca gttcaccacc
     7681 gtagtggctg ataccggaga tatcgcggca atgaagctgt accagccgca ggatgctaca
     7741 actaaccctt ctctcattct taacgcagcg caaatcccgg aatatcgtaa gctgattgac
     7801 gatgctgtcg cctgggcgaa acagcagagc agcgaccgcg cgcagcaggt tgttgacgcg
     7861 accgataagc tggcggtgaa tattggcctg gaaatcctga agctggtgcc ggggcgtatt
     7921 tctaccgaag ttgacgcgcg tctatcttat gacactgaag cgtctatcgc caaagcaaaa
     7981 cgtatcatta aactctacaa tgatgcgggt atcagcaacg atcgtatcct gatcaagctg
     8041 gcgtccacct ggcagggcat tcgcgcagcc gaacagctgg aaaaagaagg catcaactgt
     8101 aacctgacgc tgctgttctc cttcgcgcag gcgcgtgcgt gcgccgaagc gggcgtctac
     8161 ctgatctcgc cgttcgtagg tcgtattctt gactggtata aagccaatac cgacaagaaa
     8221 gactatgcgc cagctgaaga tccgggcgtg gtttccgtaa cggaaatcta cgagtactac
     8281 aaacagcatg gttacgaaac cgtcgttatg ggcgcaagct tccgtaacgt aggcgaaatt
     8341 ctggagctgg cgggctgcga ccgtctgact atcgcgccgg cattgctgaa agaactggcg
     8401 gaaagcgaag gggcgattga gcgtaagctc tctttctccg gcgaagtcaa agcgcgtccg
     8461 gaacgtatta ccgaagccga gttcctgtgg cagcatcacc aggaccctat ggcggttgac
     8521 aaactggcgg atggtatccg taagtttgcg gtagaccagg aaaaactgga aaaaatgatc
     8581 ggcgatctgc tgtaatcatt aacgcgtggc cctgatatgg gtcacgctac ctcttctgaa
     8641 acctgtctgt ccttcctttc gcagtgtatc attctgttta acgagactgt ttaaacggaa
     8701 taatcatgaa tactttacgc attggcctgg tttccatttc tgaccgtgct tccagcggcg
     8761 tttaccagga taaaggtatc ccggcccttg aagagtggct ggcatctgcc cttaccaccc
     8821 cttttgagct gcaaacgcga ctgatcccgg atgaacaggc gatcatcgaa cagaccttat
     8881 gtgaactggt tgatgagatg agctgtcatc tggtgctgac cactggcggt accggtccgg
     8941 cacgtcgcga cgtcacgccg gacgcgaccc ttgccatcgc cgaccgtgaa atgcctggtt
     9001 ttggcgaaca gatgcgccag atcagcctgc gctttgtgcc gaccgccatt ctttcccgcc
     9061 aggtgggcgt tatccgtaaa caggcgttaa ttcttaatct gcctggacag ccaaaatcga
     9121 tcaaagaaac gctggaaggc gtaaaagcgg acgatggcag cgttagcgtg ccgggcattt
     9181 ttgcgagcgt gccgtattgc atacagctgc ttgacgggcc gtatgtcgaa accgcgccgg
     9241 aagtggttgc cgctttccgt ccaaagagcg ccagacgtga gaatatgtcg tcctgaccgg
     9301 gagatactga tagtagggtt attcctcccg gtgcgggagg aataaaagag atttagtgcg
     9361 cctcgccgat tggcaaaata gtgcggccaa attgctcgtt tagcacttca cccatcgcca
     9421 gataaatagc gctggcgccg caaaccagac caacccagcc tgcgatatgg atagttgctt
     9481 cgttaccggt gatattgccg accgccagca gagcgaacag tacggtcagg ctcaggaaaa
     9541 caaattgcag cgcgcgggcg gctttcagcg taccgaagaa cataaacagc gtgaacacgc
     9601 cccacagacc taaataagcg ccgagtagct gagcgtcagg cgcatccgtc aggcccattt
     9661 tcggcatcag caggatagcg accagcgtca gccagaacga accgtaagaa gtaaaggccg
     9721 ttaaaccaaa ggtattgcct tttttatact ccagcagacc ggcaaaaatt tgcgcgatac
     9781 cgccgtagaa aatccccatc gccagaataa taccgtccag ggcgaaaaaa ccggcattgt
     9841 gcaggttaag cagaatggtg gtcatgccga agcccatcag gcccagcggt gccggattag
     9901 ccaacttagt gttgcccata attcctcaaa atcatcataa ttgaatggtg aaatagtttc
     9961 ccagaataac gagttccgta ttcggggcgc ggcataataa tcagggggaa gaggactgtc
    10021 tatgatctaa taagggggaa aagaaaatat ttccccctgt gagggcattc acgcctgaac
    10081 ggctgccatc attcgtcgca ggcaggctat ttgcaagacc gccggaatag tcacgcgata
    10141 cgcgctgccg ctcatcgctt tgacgccgtt taatgccgcg ccgaccgggc cgccaagacc
    10201 tgcgccgcgc agcaatccgt ggcccaggat gctcattgcg gcatgggtac gtaaaatgcg
    10261 ggtaagctgg gtggaaagca ggtgggagac cccttttgcc agactgcgat ctttcatgag
    10321 cagcggcagc agttcttcca gttcagaaac tttggcgtct acggcttgca gaaattcctg
    10381 cttatgcgcc gcgtccatct tctgccaggt atgacgtaaa aaatgctcca gcagttgctg
    10441 ttctatttca aacgtcgaca tgcttttatc tgctttaagt tttagccgtt ttgcgacatc
    10501 cagcagaatc gcgcggtact gttttccgtg tccgcgcaat ttgttggcga tactgtcgcc
    10561 gccgtaatgc tgaaactcgc cggcaatgag ctgccagtta cggcggtgtt gctccgggtg
    10621 accttccatc gctttgaaca gctcgttatg actaaggacg ctcgacaagc gagctttgcc
    10681 cttttcgtta tgcgtcagca aacgggcgaa atcggcgagt tgttcttcgc tacaatgctg
    10741 aagaaagtct aaatcctcgt cgtgtaaata ggtgacgttc attttcagtc tggcttttgg
    10801 aatagaaata acagcgatta atcgtcgcca atgactttaa gtctcgccat atcggaagaa
    10861 tttaccgtat gacctgagaa ggtaatcttt gatacgcagc gtttgttgtc gttatcgcta
    10921 ttaatattga tccagcctgt cgtctggcct tctttgattg aggaagggac gttcaggctt
    10981 tggctggcgc tacgcgcagt tttaaaatag acggatgcgc cgctaagttc gatatcgccg
    11041 tgatccgccg tgagttgaat gcgcttcacg atgcggcaga cgggaatttt cagcgcgaga
    11101 tcgttcgttt catttctggg catggcaata acacccagta ttttatggtc gttcgcgtgc
    11161 gcgacgctac ttaacgccag gccgaaaagc aggccgacgg aaatcgttaa cacagatcgc
    11221 atgaaatttc tctttgacgg gttcaataag caattaccgt ctatcatact ctgctcatga
    11281 caacgattca gttttgtaat cttttctttt tattacaatt tttccgtgaa tggtattcgt
    11341 tgtttaattt attttatgaa tgtttacctg tctggttttc catcgcgccc tctcgtcaat
    11401 aaaaaatttt ttcatctccc ccttgatgac gtgggttacg accccatctt gtagtcaacc
    11461 gcagtggtga gtctgaaaaa aaacgattca gggtagttga aaccgcacgt ttcgccctta
    11521 ttacagattc acaaccacat gatgaccgaa tttttagtgg agacgtttag atgggtaaaa
    11581 ttattggtat cgacctgggt actaccaact cttgtgtagc gattatggat ggaacgcagg
    11641 cacgcgtgct ggagaacgcc gagggcgatc gcactacgcc ttctatcatt gcttataccc
    11701 aggatggtga aactctggtt ggtcagccgg ctaaacgtca ggcagtgaca aacccgcaaa
    11761 acaccctgtt tgcgattaaa cgcctgattg gccgccgctt ccaggacgaa gaagttcaac
    11821 gtgacgtttc tatcatgccg tacaaaatca tcggcgccga caacggcgac gcatggcttg
    11881 atgtgaaagg tcagaaaatg gcgccgccgc agatttctgc cgaagtgctg aagaaaatga
    11941 agaaaacggc tgaagattat ctgggcgaac cggtaactga agcggttatc accgtaccgg
    12001 cttactttaa cgatgcgcag cgtcaggcta ccaaagatgc tggtcgtatc gcggggctgg
    12061 aagttaaacg tatcatcaac gaaccgactg ccgcagcgct ggcttacggt ctggataaag
    12121 aagtcggcaa ccgtactatc gcggtttacg acctcggtgg tggtactttc gatatctcta
    12181 ttatcgaaat cgacgaagtt gatggcgaaa aaacctttga agttctggca accaacggtg
    12241 atacccacct gggtggtgaa gacttcgata cccgcctgat caactacctc gttgacgagt
    12301 ttaagaaaga tcagggcatc gacctgcgta acgatccgct ggccatgcag cgcctgaaag
    12361 aagccgcaga aaaagccaaa atcgagctgt cttctgcgca gcagaccgac gtgaacctgc
    12421 cgtacattac cgcagatgcc accggtccga aacacatgaa catcaaagtg acccgtgcga
    12481 aactggaaag cctggttgaa gatctggtga accgttctat cgagccgctg aaagtcgcac
    12541 tgcaggacgc tggcctgtcc gtgtctgata tcaacgacgt gatcctcgtc ggcggtcaga
    12601 cccgtatgcc aatggtgcag aaaaaagtgg ctgagttctt cggtaaagag ccgcgtaaag
    12661 acgttaaccc ggacgaagct gtggctatcg gcgcagcggt acagggcggc gtattgaccg
    12721 gtgatgtgaa agacgtactg ctgctggacg ttaccccgct gtctctgggt atcgaaacga
    12781 tgggtggcgt gatgactccg cttatcacca aaaacaccac catcccgacc aagcacagcc
    12841 aggtgttctc tactgcggaa gacaaccagt ctgcggtaac catccatgtg ctgcagggtg
    12901 agcgtaaacg tgcgtctgat aacaaatctc tgggtcagtt caacctggat ggcatcaacc
    12961 cggcgccgcg cggtatgccg cagatcgaag tcaccttcga tatcgatgct gacggtatcc
    13021 tgcacgtctc cgcgaaagat aaaaatagcg gtaaagagca gaagatcact atcaaggcgt
    13081 cttctggtct gaacgaggaa gaaattcaga aaatggttcg cgatgcagaa gcgaacgctg
    13141 aatccgaccg taagttcgaa gagctggttc agacccgtaa ccagggtgac catctgctgc
    13201 acagcacccg taagcaggtt gaagaagcag gcgataaact gccggctgat gacaaaaccg
    13261 ctatcgagtc tgcgctgagc gcgctggaaa ctgccctgaa aggcgaagat aaagccgcta
    13321 tcgaagcgaa aatgcaggag ctggcgcagg tttcccagaa actgatggaa atcgctcagc
    13381 agcaacatgc gcagcagcag gctggctccg ccgacgcttc tgcaaacaat gcgaaagatg
    13441 acgacgttgt cgacgctgag tttgaagaag taaaagataa aaaataatcg ccctttgaac
    13501 gggtaattac tggcacgggc gaagaggttt cctctccgcc cgtgtatgca tgttaagggc
    13561 agataaaaag agatggcgaa aagagattac tacgagattt taggcgtttc caaaacagcg
    13621 gaagagcgtg aaatcaaaaa ggcgtataag cgcctggcca tgaaatatca tccggaccgc
    13681 aatcagggtg ataaagaggc cgaagctaag tttaaagaga ttaaagaagc ctacgaagtg
    13741 ctgaccgatg cgcaaaaacg cgcagcctac gatcagtatg gtcacgccgc gtttgaacaa
    13801 ggcgggatgg gcggcggatt tggcggcggc tttaatggcg gcgctgattt cagtgatatc
    13861 tttggtgacg tttttggcga tatctttggc ggcgggcgtg gtcgccaacg tgcggcgcgt
    13921 ggggctgatt tgcgttataa catggatctc accctggaag aagcggtgcg tggcgtgacc
    13981 aaagagatcc gtattccgac gctggaggag tgcgacgttt gccacggcag cggcgcgaaa
    14041 gctggtacgc aaccgcaaac ctgtccgacc tgtcatggtt ctggtcaggt acagatgcgc
    14101 cagggattct ttgctgtaca gcagacctgc ccacactgtc agggccgcgg tacgctgatc
    14161 aaagatccgt gccataaatg tcacggtcat gggcgtgttg aaaagagtaa aactctgtcc
    14221 gttaaaatcc cggcgggcgt ggataccggc gatcgtattc gtctggcagg cgagggcgaa
    14281 gcgggcgagc atggcgcacc ggcaggcgac ttgtacgttc aggtccaggt gaaacaacac
    14341 cctattttcg agcgtgaagg caataatctt tattgcgaag tgccgatcaa ctttgcgatg
    14401 gcggcgctcg gcggtgaaat tgaagtgccg acgttagatg gtcgcgtgat gctgaaagta
    14461 ccgagcgaaa cacaaacggg caagctgttc cgtatgcgcg gcaaaggcgt gaagtccgta
    14521 cgcggtggcg cgcagggcga tttgctgtgc cgtgtggtag ttgaaacgcc ggtcggtctg
    14581 agcgaaaaac agaagcaatt gctaaaagat cttcaggaaa gttttggcgg cccgacggga
    14641 gagaaaaaca gcccgcgttc aaaaagcttc tttgacggcg tgaaaaaatt ctttgacgat
    14701 ttgactcgct aacctttttc ccgttgtatt tttcttcagc ccgggtgtat gtatatccgg
    14761 gctttttttc tgcctgtacg cgcccaggct tctgctaaac gcatcgtatc ctctcatttg
    14821 ttggtatttt gttttactga taaacaaatt gatgttaatc agcaggtttg catacgctca
    14881 ttttaaaaaa aaatgtaatg tgatgacatt aacgattgct tttttagacg ctgtgaattg
    14941 atttatcttg agtattatct atattgcttt ttttagtttc cggaggcaga cagcgaatgg
    15001 gatcgaaagg tgccaacaag agctttgatt ataatttaat caaaattctt gacgctgtta
    15061 ttttgtcagg aaatgcggct atggcggcaa aaaagttagg cattacaccg gctgccgttt
    15121 ctctggcgtt aaagcgcctg cagagttatt acccggaaga actgtttagc agagggaaag
    15181 gcgggctcat ccccactgct aaggctgtcg acattcacca aaatttcagt caggtgatga
    15241 aactggtgga tgacacattt ctctgtaata gcaaaaaaga tgaagcgttc cagataacgt
    15301 tattaggcag tgatattgtt gaaagctatt atctttctca gctctataac agcgatatat
    15361 ttgaccgtat tttgataaat catttctccg tcagaaatat gagtcgggag catatcagcg
    15421 aacttctgtt tactgcgcaa ggcgatctgt tgattagtgc cgaacctttg ctggagtccg
    15481 gcatagagaa tcaaatcatt gatagtttta aatcatttgt ttgtatctgt agcagtaaac
    15541 acatgctgag taccctctcg caactgtcgc tacatcattt ttattcttcg cgtcatgcgt
    15601 tatatcagcc ggggatgggg gcttcagtga tatatcatga tagcgagtta tttaaggatg
    15661 agctttacta tactggcagg cgtattgtcg gctatcgtag tgattcactt aacggtttga
    15721 tgagcatgat cgaacgaacc tcattgattg cattgatgcc tttgaaatta gcgctttttt
    15781 ataaaaatca tcgtaaatat gacattaaat ttattcagcc tccgcccgaa ctggccttta
    15841 agtcagttca ggtctatgca tcctggaaga aaaatagtag aaatatatcg acgattaatg
    15901 agatggtaag tatgttgcaa acactttcct ccttccgtcg ctaacacacc tcatttttac
    15961 gctttgattt aatatggttt taaatgatgt gctttgattt ttacccttct gacagggcgc
    16021 ttacactcct tgtgttaatt attcatttat aatgatttcg gggtgttaaa atgtctattc
    16081 ccaaccatgt gtcgacaacg gaagttgtgc tattggagct agagatctta ctcactatta
    16141 tttcgattgg cgcgtgggga ggctttgtta gctatctttt acgcaaagat aagacagaat
    16201 ataatagttc tcatgaaagt attaaatatt gcttaacgca gatcgtgatt tcctgcttca
    16261 ccagcttttt gttaagcgcg attgcgatcg aaaaagaatg cagtttcaat attgtcctgt
    16321 tggcggcagg cttaggcggt gttttcgcga gtccgatctt aaaaattctt gggcggcgaa
    16381 ttaaaaaaat tatcggagga aataattcag attaattgtc attcgcaata tcaggctcat
    16441 ccgtgagcct tttacgcgtc ttttttcagc ctggtctagg tcactctgtt cttgatccag
    16501 ccataaataa attgttcgtt attgtggttt ttctcagcaa cgtttaagta gtacatgccc
    16561 tgactgcaat tgagggcttt caccaaaacg gcttcccctt cctggcctcg ccaggccaaa
    16621 taatgttcga gagcggcaag cgtccgcggg ccaatattgc catccacatg aacatccggg
    16681 tagcgtttac cttcgtgatt aaagacgttc agccagcgtt gcagccacgc gctggggtgg
    16741 taatcgccta tgttgactgc cgcatcgcac agctcgaatg agactggcca cgatagcgtc
    16801 gagatgacat caaagcctgg ttttatccag taatcctctt cgagaatcgc gtaggcttca
    16861 gcgtgggtca gatcccgcat atcgccagca tagccatgcg ctcgcgccgt ggcttcggta
    16921 atgccccaat gagtggcgcc gcctttatct ttagggttaa atacgtaacc gccttcaagc
    16981 gcaataattc catctataat tggattcatc ttccctttcc ttcgcttagt gaatatgcag
    17041 atacatgaga gaacctaacg ttactgaaaa tacggtcgtc agggcagcga tggtttgccg
    17101 tacaatctgt ttttttcttc cctttgtttc gctatccgtc gcgataatgg cgatatcact
    17161 attcactttg agaccttgtc ttggaatggt aataaaaaga tcattaatac caagcgcttt
    17221 aaggtcacgt ctgattaaat agagaatctg cgttagattt gcatcattaa catagtggct
    17281 tcgacttccc cataacgcag tggttatttt ttgtcgctcg ataatctcca gatgagcatt
    17341 ctcgatgatg aaactgagac atttggctct catcgcagtc attttaataa cctgtgaatt
    17401 tgagaccgtc ctcagttcat atttaccttc attgtaaatg caattgctat taatgatata
    17461 agttttcata acgtcttcct ttagaaatgt acatcctggt tgtctgtggt gactatattg
    17521 tatgagaaat gtctt
//
LOCUS       DAJVKX010000089        17531 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.089, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000089 DAJVKX010000000
VERSION     DAJVKX010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17531
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.089"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(167..3040)
                     /gene="gcvP"
                     /locus_tag="OPY25_003080"
     CDS             complement(167..3040)
                     /gene="gcvP"
                     /locus_tag="OPY25_003080"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HCS0928638.1"
                     /translation="MTQTLSQLENRGAFIERHIGPDAAQQQEMLNAVGAESLNALTGQ
                     IVPKDIQLATPPQVGEAATEYAALAELKAIAGRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVAADVHPQTLDVVRTRAKTFGFDVIVDDADKVLDHQDVFGVLLQ
                     QVGTTGEIHDYGTLISELKARKVIVSVAADFMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEFKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAAVLARAEAAEINLRSDIHNAVGITLDETTTRENVAQLFNVLLGDSHGLNIE
                     TLDKDVALDSRSIQQGMLRDDAILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYHQMISQLSDWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHGSRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLDDLRAKAEQHAANLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKQASQVAILNANYIASRLKD
                     AYPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESEGKAELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISDYQ"
     gene            complement(3203..3592)
                     /gene="gcvH"
                     /locus_tag="OPY25_003081"
     CDS             complement(3203..3592)
                     /gene="gcvH"
                     /locus_tag="OPY25_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HCS0928639.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            complement(3618..4712)
                     /gene="gcvT"
                     /locus_tag="OPY25_003082"
     CDS             complement(3618..4712)
                     /gene="gcvT"
                     /locus_tag="OPY25_003082"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HCS0928640.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDA
                     GMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLF
                     TDQQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREK
                     GHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            complement(5167..6369)
                     /gene="ubiI"
                     /locus_tag="OPY25_003083"
                     /gene_synonym="visC"
     CDS             complement(5167..6369)
                     /gene="ubiI"
                     /locus_tag="OPY25_003083"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HCS0928641.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLDHVVPQQLANDA
                     PPQLRVSAINAASEKLLTRLGVWSNIVARRASCYHGMEVWDKDSFGRITFDDASMGYS
                     HLGHIVENSVIHYALWQKAQQAADITLMAPAELQQVAWGENDAFLTLKDGAMLTARLV
                     IAADGANSWLRNKADIPLTFWDYRHHALVATIRTEEPHGAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPQDAERMQQSGDEAFNQALTIAFDNRLGLCRLESERQVFPLTGRYA
                     RQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELVDDLCRLQRQGKDIGQHLYLRR
                     YERSRKHSAAMMLAGMQGFRDLFAGENPAKKLLRDIGLKLADTLPGVKPQLLRQAMGL
                     NDLPQWLR"
     gene            complement(6498..7676)
                     /gene="ubiH"
                     /locus_tag="OPY25_003084"
                     /gene_synonym="visB"
     CDS             complement(6498..7676)
                     /gene="ubiH"
                     /locus_tag="OPY25_003084"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461973.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HCS0928642.1"
                     /translation="MSVIIVGGGMAGATLALAISQFSHGTLPVHLIEAKAPEADGHPG
                     FDARAIALAAGTCQQLARIGVWQAISDCATAINTVHVSDRGHAGFVTLDAQDYSLAAL
                     GHVAELHDIGLRLFALLRKAPGVTLHCPERVASVSRTQQQVNVTLENGNVIAGSVLVA
                     ANGTHSALASACGVDWHQEPYEQLAVIANVATAIPHQGRAFERFTPNGPLAMLPMSHG
                     RCSLVWCHPLDQRDEVLSWSDAQFCHALQAAFGWRLGRITQAGKRSAYPLALTTAAKV
                     FTHRTVVVGNAAQTLHPIAGQGFNLGLRDVMSLAETLVAAQDAGEDIGAWHVLSRYQQ
                     RRQVDRDTTIGVTNGLVHLFANRWAPLVIGRNIGLMAMELLPPARDALAQRTLGWVAR
                     "
     gene            complement(7673..8989)
                     /gene="pepP"
                     /locus_tag="OPY25_003085"
     CDS             complement(7673..8989)
                     /gene="pepP"
                     /locus_tag="OPY25_003085"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HCS0928643.1"
                     /translation="MTQQEYQRRRQALLAQMQPGSAALIFAAPEATRSADSEYPYRQS
                     SDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGV
                     DRALAFSEINQQLFQLLNGLDVVYHAQGEYAYADEIVLAALEKLRKGSRQNLTAPATM
                     TDWRPIVHEMRLFKSPEEIAVLRRAGEISALAHIRAMEKCRPGMFEYQLEGEIHHEFN
                     RHGARYPSYNTIVGSGENGCILHYTENESEMRDGDLVLIDAGCEYKGYAGDITRTFPV
                     NGKFTPAQREIYDIVLESLETSLRLFRPGTSIQQVTGEVVRIMITGLVKLGILQGEVD
                     QLIAENAHRPFFMHGLSHWLGLDVHDVGVYGPDRSRILEPGMVLTVEPGLYIAPDADV
                     PEAYRGIGVRIEDDIVITETGNENLTAGVVKKADDIEALMAAARQQ"
     gene            complement(9015..9593)
                     /locus_tag="OPY25_003086"
     CDS             complement(9015..9593)
                     /locus_tag="OPY25_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecA family protein"
                     /protein_id="HCS0928644.1"
                     /translation="MSIQNEMPGYDEMNRFLNQQGAGLTPAEMHGLISGMICGGNNDS
                     SWQPLLHDLTNEGLAFGHELAQALRKMHAATSDALEDDGFLFQLYLPEGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDESEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTRQQPTAPEVRKPTLH"
     gene            9760..10089
                     /gene="zapA"
                     /locus_tag="OPY25_003087"
     CDS             9760..10089
                     /gene="zapA"
                     /locus_tag="OPY25_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCS0928645.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKVR
                     TRVTNTEQLVFIAALNISYELTQEKAKTRDYAASMEQRIRMLQQTIEQALLDQGRITE
                     KTGQNFE"
     gene            10131..10314
                     /gene="ssrS"
                     /locus_tag="OPY25_003088"
     ncRNA           10131..10314
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="OPY25_003088"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            10335..10931
                     /locus_tag="OPY25_003089"
     CDS             10335..10931
                     /locus_tag="OPY25_003089"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCS0928646.1"
                     /translation="MTQLPELSLSRQEIRRMIRQRRRALTPEQQRRFGQQAAARMLSF
                     PPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVYLPVLHPFSPGNLLFLHYHPQSA
                     LVTNRLNIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQH
                     KILPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKIWEW"
     gene            complement(11312..12544)
                     /gene="serA"
                     /locus_tag="OPY25_003090"
     CDS             complement(11312..12544)
                     /gene="serA"
                     /locus_tag="OPY25_003090"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCS0928647.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEYHKGALDA
                     EQLKASIRDAHFIGLRSRTHLTEEVINAAEKLVAIGCFCIGTNQVDLNAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMHIYFYDIENKLPLGNATQVQHLSELLNMSDVVSLHVPENASTK
                     NMMGAKEIALMKPGSLLINAARGTVVDIPALCDALATKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVILTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNQIFAEQGVNIAAQYLQTSARMGYVVIDIEADGDVAEK
                     ALLAMKAIPGTIRARLLY"
     gene            complement(12810..13469)
                     /gene="rpiA"
                     /locus_tag="OPY25_003091"
     CDS             complement(12810..13469)
                     /gene="rpiA"
                     /locus_tag="OPY25_003091"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCS0928648.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKGLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQNV
                     VTDNGNVILDVYGMEILDPIALENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            13622..14515
                     /gene="argP"
                     /locus_tag="OPY25_003092"
     CDS             13622..14515
                     /gene="argP"
                     /locus_tag="OPY25_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HCS0928649.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTACCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPES
                     RMMRKVTDALLEYGHKVLRQD"
     gene            complement(14781..15527)
                     /locus_tag="OPY25_003093"
     CDS             complement(14781..15527)
                     /locus_tag="OPY25_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HCS0928650.1"
                     /translation="MKFKVMALAALVGLSAMSAQASELPEGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYLSFLEQNQIAKKDISAANLRTQPDYDYQNG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDDAIHQAQALAAGFNSKLGPVYSVRYHVSNYQPSPVVRMMKAADAAPVSAQETYEQ
                     PTIQFDDQVDVVFQLEPGTGQTSTTAASTQ"
     gene            complement(15621..16256)
                     /gene="argO"
                     /locus_tag="OPY25_003094"
     CDS             complement(15621..16256)
                     /gene="argO"
                     /locus_tag="OPY25_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HCS0928651.1"
                     /translation="MISYYFQGVALGAAMILPLGPQNAFVMNQGIRRQYHLMIALLCA
                     LSDLVLISAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGALKTAMSSNLELASAE
                     VMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLAMEPKRWFALGTISASFLWF
                     FGLALLAAWLAPRLRTAKAQRIINILVGVVMWLIAFQLAREGVAHMHALFN"
     gene            complement(16457..17317)
                     /locus_tag="OPY25_003095"
     CDS             complement(16457..17317)
                     /locus_tag="OPY25_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HCS0928652.1"
                     /translation="MEDLNVVDSINGAGTWLVRNQALLLSYAVNIVAAIAIIIIGLIV
                     ARVISNTVNRLMRARHIDATVADFLSALVRYGVIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLNVQIFSTTMRAVDG
                     KIIVIPNGKIIAGNIINYSREPVRRNEFIIGVAYDSDIDQVKQLLTTIIESDDRILKD
                     REMTVRLNELGASSINFVVRVWSKSSDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKDNAAE"
BASE COUNT         4090 a         5064 c         4478 g         3899 t
ORIGIN      
        1 gccaggttgc ctgacaggag ccaacgattt actgtaatat attgaattag taacactttg
       61 tagcctgaat aaggcactca cactgcatcc gacataaaca aaacgcactt tattaacaag
      121 ctgaaaaggc gccgaagcgc ctttagaaaa cagtcgaatc agtaaattac tggtagtcgc
      181 taatcggtac gcaggagcag aacaggttac ggtcgccata aacatcatcc agacgtttca
      241 ccgtcggcca gtatttgtct gccacgcctg ccgggaatac ggcaacttca cggctgtacg
      301 gatgcgccca ctcggcgacc agttcgctct gaatgtgcgg cgcgttcacc agcgggttat
      361 cttccagcgg ccagacaccg gctttcacct ggtcaatctc tgcgcggata gccagcatcg
      421 catcgataaa gcgatccagc tcagccttac cttcagattc cgtcggctct accatcagcg
      481 tgcccgccac cgggaacgac atggttggcg catggaaacc atagtcgatc agacgcttgg
      541 caatatccag ctcgctgatg ccggtttctt ctttcaatgg gcgaatatca agaatacatt
      601 cgtgcgccac tcggccatcg cgaccggtat acagtaccgg gtacgcgtct ttcagacggc
      661 tggcaatgta gttagcgtta agaatcgcga cctgacttgc ctgcttcagg ccttctgcgc
      721 ccatcatgcg gatgtacatc caactaatcg gcaaaatgga ggcgctgccg aacggcgccg
      781 cagacaccgc gccctgacgg gtgagcatcc cttcaatttg caccacgcta tgacccggta
      841 cgaatggcgc cagatgcgct ttcacgccga tcggtcccat gcctgggcca ccgccgccgt
      901 gcggaatgca gaaagtttta tgcaggttaa gatgcgaaac gtccgcgcca ataaagcccg
      961 gtgaggtaat gccgacctga gcgttcatgt tcgcgccgtc aaggtaaacc tgaccgccga
     1021 actggtgcac aacttcacac acttcacgga tcgtttcttc atagacgccg tgggtggacg
     1081 gataggtcac catgatgcaa gagaggttcg cagcatgttg ttctgctttg gcccgcagat
     1141 cgtccaggtc gatgttgccg ttcttatcac acgccacaac caccacctgc attcctgcca
     1201 tatgtgcaga agcagggtta gtgccgtgag cagaggccgg aatcaggcag atatcgcgat
     1261 gcccttcgtt gcggcttccg tgataatgac gaatcgccag cagccccgcg tactccccct
     1321 gcgcgccgga gttcggctgc atacagacgg cgtcgtaccc ggtgagtttc accagccagt
     1381 cagaaagctg gctaatcatc tgatgatatc cttcggcctg ctccggcggg cagaacgggt
     1441 gcagttcagc gaattccggc caggtgatag ggatcatctc ggcggcggcg ttcagcttca
     1501 tggtgcagga acccagcggg atcatcgcct ggttcagcgc cagatcttta cgctccagcg
     1561 agtgcatata gcgcatcatc tcggtttcgc tgtggtagcg gttaaatacc ggatgcgtca
     1621 gaatcgcatc gtcacgcagc ataccttgct gaatggaacg gctatcaagc gccacgtctt
     1681 tatccagtgt ttcaatgttc agaccgtggc tgtcgcccag caaaacattg aacaactgcg
     1741 ccacattctc acgggtggtg gtttcatcaa gggtaatacc caccgcgtta tgaatatcgc
     1801 tgcgcagatt gatctctgcc gcttccgcac gcgccagtac cgcagcttta tcagctactt
     1861 ccacacacag cgtgtcaaag tagtgcgcat gacgcagctt taagcctttc tgttgcagac
     1921 cggccgccag aatatcggtc aggcggtgga tacgattcgc aatgcgtttc aggccaaccg
     1981 gtccatgata aacggcatac agactggcga tgttagccag cagtacctgc gaggtacaaa
     2041 tgttggagtt cgctttctca cggcggatat gctgctcgcg agtctgcatc gccatgcgca
     2101 gtgcggtatt gcccgccgca tcttttgaga cgccgataat acggcctggc atggagcgtt
     2161 taaattcgtc tttggcggca aagaacgccg cgtgcgggcc accgtaaccc atcggtacgc
     2221 caaaacgttg cgcagagccg aaaacaatat ccgcgccctg tttgcccggc gcggtaagca
     2281 gcaccaacgc cataaaatcg gcggcgacgc tgacaatcac cttacgggct ttgagttcgc
     2341 taatcagcgt gccgtagtcg tgaatttcgc ccgtggtgcc tacctgttgt aacagcacgc
     2401 caaatacgtc ctgatgatcc agcactttgt ccgcgtcatc gacaatcacg tcaaagccaa
     2461 aggttttggc gcgtgtacgt accacgtcca gcgtttgcgg atggacgtca gccgccacaa
     2521 agaaacggtt ggcatttttc agtttgctga cgcgctttgc catcgccatt gcttcggcgg
     2581 cagcggtggc ttcgtcaaga agagaagccg aagccatatc cagtccggtc agatccagcg
     2641 tcacctgttg gaagttgagc agcgcttcca ggcgcccctg agagacttcc ggctgataag
     2701 gagtgtaggc ggtataccag cctggatttt ccagcatgtt gcgcaggata accggcggta
     2761 gctgcacggc ggtgtagccc atgccaatgt aggacgtgaa gcgcttgtta cgcccggcga
     2821 tggcttttaa ttccgccagt gcggcatatt cggttgccgc ctcgccaacc tgcggcggag
     2881 tcgcgagctg aatgtctttc ggcacaatct gacctgtcag cgcgtttaac gactcggcgc
     2941 caaccgcatt cagcatctct tgctgctgcg cggcgtccgg tccgatgtgg cgttcaatga
     3001 aagcgccgcg gttttcaagc tggcttagcg tctgtgtcat gggcgatggt tcctgaaacg
     3061 tgcagtgaat cgtaggtgtc tctaactcaa ttgcccggtg gcgctgacgc ttaccgggcc
     3121 tacgcgtgcg aaaacgaata cgcaaaatca ttcgcgttgc agtgagtagg ccggataagc
     3181 attagcgcca tccggcacaa cattattcgt cttctaacaa tgcctcatac gcggtggcat
     3241 ccagcagcga ttcaagctcg ctttcatcgc tggctttgat tttaaagatc cagccaccgg
     3301 catacggttc gctgttcacc agctccgggg agtcgctcag cgcatcgttt accgccacga
     3361 tctcgccgct taccggcgca taaatgtcgg acgccgcttt tacggactcc gccacggcgc
     3421 agtcgtcgcc cgcgcttacg gtcgcgccga cttccggcag atcaacaaaa accatatcgc
     3481 ccaacagctc ctgagcgtgt tcagtaatgc caacggtgta agtgccatcc gcttctttac
     3541 gcagccattc gtgttctttg ctgtatttca gttctgcggg tacgttgctc atcaattaat
     3601 ctccaaaaaa ggatgaatca cgcgacggct ttgccgttac gcacaaaaac aggtttagtc
     3661 acttttaccg gcatttcacg gttacgaatt tgtacaatcg ccgtctcgcc gatgcccgcc
     3721 ggaacgcgcg ccagcgcaat gctgtagccc aacgttgggg aaaacgtccc gctggtgata
     3781 atgccttctt gctgattgcc ctgcgcatcg gtaaaacgca ccggcagttc attacgcaat
     3841 acgcctttct cggtcatcac cagaccgaca agctgctcat ggcctttttc acgctgcatc
     3901 tccagcgcct cacggccaat aaagtcgcgg tcagcaggtt cccaggcgat agtccatccc
     3961 atattagccg ccagcggaga gataccttca tccatctcct gaccgtacag gttcatgcct
     4021 gcttccagac gcagcgtgtc gcgcgcgcca agaccgcacg gcttcacgcc cgcctccacc
     4081 agcgcacgcc agaaatccgc cgctttttca ttcggcatgg cgatttcata gcccgcttcg
     4141 ccggtataac cggtggtggc gataaacaga tcgcccgcct gaacgccgaa gaacggcttc
     4201 ataccttcta ctgcatggcg ctgttggtca gtaaacagag tcgccgcttt ttcctgcgca
     4261 ttcggcccct gtaccgcaat cagcgacagg tcgtcacgaa cggtgatgtc gatggcataa
     4321 ggttcagcgt gttgggtaat ccaggagagg tctttttcgc gggtggcgga gttaacaacg
     4381 agacggaaga aatcttcagt gaagtagtag acaatcaggt catctatcac accgcccgat
     4441 gcgttaagca taccggagta gagggcttta cccgtcttcg ttagcttcgc gacgtcgttt
     4501 gccagcagat aacgtagaaa ctctcgtgta cggctaccat gaagatcgac aatggtcata
     4561 tgcgatacat caaacatccc ggcatcggtg cgcacagcgt ggtgttcatc aagctgagag
     4621 ccgtaatgca ggggcatcat ccagccatga aaatcgacca tgcgggcgcc gcatagcgtg
     4681 tgttgttcgt acaaaggcgt ctgttgggcc atcttttcct cgttgaatta gcgggggcta
     4741 acaaccattt tcatgggaaa tcttcgccac gaaacctggc atcgacgccc tttttcctgc
     4801 gccgacgcaa acgttctctt gctcctgaac ttaccaccga accaggcgct aaaccataag
     4861 gctgaattta ccatcacatt agcttatgac taaaaaacgc taaaatccca tcagcacaaa
     4921 aaaccactat tacgctaaat aacttccata aaaatgaagc tgatacgatt tatcacaaca
     4981 taaattaata ttaaatgcgg aaaaaatgtc gaaaatcgcg ttctccaaaa atagtggcat
     5041 tagaaaatat aatgcgaaat aagcggtgaa attagattat ttcaaacgag gaaagccccc
     5101 cggcgcgata gccgggaaag caaagtgtga cgggtttcaa actcttgctg gcgtgcagtc
     5161 agacgcttaa cgaagccatt gcggaaggtc gtttagcccc attgcctggc gaagcagttg
     5221 gggtttgacg ccggggagcg tgtccgccag tttcagtccg atgtcgcgca gcaatttttt
     5281 tgccgggttt tcgccggcaa acaggtcacg aaaaccttgc atcccggcaa gcatcatcgc
     5341 cgcgctatgt ttacggctac gctcataacg acggagataa agatgttggc caatgtcttt
     5401 gccctggcgc tgaagccggc acagatcgtc caccagttcg gccgcgtcca taaaaccgag
     5461 gttgacgcct tgccctgcca gcggatggat ggtgtgcgcg gcatcgccga ccaacgccag
     5521 acgatgcgcg gcaaactggc gagcatagcg gcccgtcagc ggaaaaacct gccgttcgct
     5581 ttccaggcgg cataagccca gccgattatc gaaggcgata gtcaacgcct ggttaaacgc
     5641 ctcgtcgccg ctctgttgca tacgctccgc atcctgcgga gaaagcgacc agacaatgga
     5701 acacagatgc ggatcgctta acggcaaaaa cgccagaata ccttcaccat gaaacacctg
     5761 gcgagcaacc gcgccgtgcg gctcttcggt gcggatagtc gctaccagcg catggtgacg
     5821 gtagtcccag aaagttaagg gaatatccgc tttgttacgc agccaggagt tggcgccatc
     5881 cgcggcaatc accagacgcg cggttaacat cgcgccgtct tttaaagtca ggaaggcgtc
     5941 attctctccc caggcaacct gctgtaactc cgctggcgcc attaaggtga tatccgccgc
     6001 ttgctgcgct ttttgccaca gtgcatagtg aatgacgctg ttttcaacaa tatgccccag
     6061 atggctatat cccatgcttg cgtcatcaaa cgtaatacgg ccaaagctgt ctttatccca
     6121 gacttccata ccgtggtagc aacttgcccg tcgcgccaca atgtttgacc atacgccaag
     6181 acgggtaagc agtttttcgc tggcggcatt aatcgccgac acccgaagct gaggcggcgc
     6241 atcgttcgcc aactgctggg gaacaacgtg atccagtacc gcaacgcgca aaccgctccc
     6301 ctgcaagccg caggcgacag ccagtcccac catgcctccg ccaactattg ctacatcaac
     6361 actttgcact atttactcct ggaaaccgga acaatcaaaa ccgtaggccg gataaggcgt
     6421 ttacgccgcc atccggcatt tttacgaaca cgatgccgga tggcggcgta aacgccttat
     6481 ccggcctaca gatctgctta acgcgcaacc caacctaagg ttcgctgtgc cagcgcatcg
     6541 cgcgcaggtg gtaataattc catcgccatt aaaccgatat tgcgcccaat aaccagcggc
     6601 gcccaacgat ttgcaaacag atggaccaga ccgttcgtta cgccaatcgt cgtatcccgg
     6661 tcaacctgac gacgctgctg atagcgcgat aacacgtgcc aggcgccaat atcctcgccc
     6721 gcgtcctgtg ccgcgaccag cgtttccgcc aggctcatga catcgcgcag accgagatta
     6781 aacccttgtc cggcgatagg atgcaacgtc tgcgccgcat tgccgaccac gacagtccgg
     6841 tgagtaaaca ctttcgccgc cgtagtcagg gcaagcggat acgcgctgcg cttacccgcc
     6901 tgagtaattc gccccagccg ccagccgaac gcggcctgca acgcatgaca gaactgcgcg
     6961 tcggaccagc tcagcacctc atcgcgctgg tcgagcgggt gacaccaaac cagcgaacat
     7021 cggccatgcg acatcggcaa catcgccagc gggccattgg gggtaaaacg ttcaaaggcg
     7081 cgtccctggt gcgggatagc ggtcgcgaca ttcgctatca ccgctaactg ttcgtaaggc
     7141 tcctgatgcc agtcaacgcc gcaggctgat gccagcgcgg agtgggtacc gttagccgcc
     7201 accagcacgc tgccagctat cacattgccg ttttccagag tgacgttaac ctgctgttgg
     7261 gtacgcgaca cgctggctac gcgctccggg cagtgcagcg taacgcctgg cgctttacgc
     7321 aagagcgcaa acagacgcag cccgatatca tgcagctccg caacgtgacc caacgctgcc
     7381 aggctgtaat cctgcgcgtc tagagtcaca aatccggcat gaccgcgatc gctgacgtgt
     7441 acggtgttga ttgccgttgc gcaatcggaa atcgcctgcc agacgccaat tcgcgccagt
     7501 tgctggcaag tgcccgccgc cagcgcaatc gctctggcgt caaagccggg atgaccgtcg
     7561 gcttcaggcg ctttcgcttc aatcaggtgt accggcaacg tcccatgact gaactgagag
     7621 atggccagcg ccagcgttgc gcctgccatg ccgccgccaa cgataatgac gctcattgct
     7681 gccgcgccgc cgccattaat gcctcaatgt catccgcctt cttcacaacg ccagcggtca
     7741 ggttttcatt accggtttcg gtaatgacaa tgtcatcttc aattcgaacg ccaatgccgc
     7801 gatacgcttc cggcacgtcg gcatccggcg cgatatagag gcctggctct acggtcagca
     7861 ccatgcccgg ctccaggatg cgggagcgat ccggcccata aacgccgaca tcatgaacat
     7921 ccagccccag ccagtggctc aagccatgca taaagaaagg acgatgcgca ttctcggcaa
     7981 tcagttgatc aacctctcct tgcaaaatcc ccaacttcac cagcccggtt atcatgatgc
     8041 gcactacttc gccggtcacc tgctgaatag aggtaccagg acggaacagt cgcaggctgg
     8101 tctccagcga ttccagaacg atgtcataaa tttcacgctg agctggcgta aatttcccgt
     8161 tcaccgggaa agtacgcgtg atgtcgcccg cgtaaccttt atattcacag cccgcgtcga
     8221 taagcactaa atcgccgtcg cgcatttcac tttcgttttc agtgtaatgc aggatacagc
     8281 cattttcgcc gctgccgaca atggtgttat aggagggata gcgcgcgcca tggcgattaa
     8341 attcgtggtg aatttcaccc tccagctgat actcaaacat ccccggacgg catttttcca
     8401 tcgcgcggat atgcgccaga gcgctaattt ccccggcgcg gcgcaggaca gcaatctctt
     8461 ccggcgattt gaacaggcgc atctcatgga cgatcggtcg ccagtcagtc atggtggccg
     8521 gcgcggtcag attctggcgg gagcctttac gcagcttctc cagcgcagcc agaacaatct
     8581 cgtcggcata cgcatattcg ccctgcgcgt ggtacaccac atccagacca ttaagcaact
     8641 gaaagagttg ctggttgatt tcgctaaacg ccagcgcccg gtcaacgccc agtttttccg
     8701 gcgcggcatc ctgtcctaaa cggcgaccaa accagatttc cgccgtcagg tcgcgaacgc
     8761 ggttgaacaa aacgctgtgg ttgtgggtgt catcactctt aatcagtacc agcacggctt
     8821 ccggttcgtt aaaaccggtg aaataccaga agtcgctact ctggcgatac ggatattcac
     8881 tgtctgcgct gcgcgtcgcc tccggcgcgg caaagatcag cgcggcgctg ccgggctgca
     8941 tttgcgccag taatgcctgg cgacggcgtt ggtattcctg ctgagtcatg acatggcctc
     9001 catttcgttt tttcttagtg tagcgtcggt ttacgcactt ccggcgcggt cggctgttgg
     9061 cgcgtgaaag tgtcatgaca taacagcgcc gcaacacgga catattcgat gatctcttcg
     9121 agcgacatct ccagctcttc ctgatcttcg ctctcatcat aaccaagctg cgcaatatta
     9181 cgcaggtcgt caatcgcttc acccgtttcg ccggtgactt tatcaagttt aggctgcgtt
     9241 acgccgaggc caagcaaaaa gtggttaacc cacccggcta atgcatctgc gcgatcgaat
     9301 acgctgacat cgtcgccttc aggcagataa agctgaaaaa gaaagccgtc gtcttccagc
     9361 gcgtcgctgg tcgccgcgtg cattttgcgc agcgcctgag caagctcatg cccgaaggcc
     9421 agaccttcgt tcgtcaggtc atgcaacagc ggctgccatg agctgtcgtt gttgccgccg
     9481 caaatcatcc cgctgattaa accatgcatt tcagccgggg tcagaccggc cccttgttga
     9541 ttcaaaaacc ggttcatttc gtcgtaacca ggcatttcgt tctgtataga cataagcatt
     9601 cgtcatcaaa gggaggatat tcatgatatg ctaccacttt ggaccctggt gaaccagaaa
     9661 agggcttgta tcttcacacc agggtagcta tagtgtcgcc ccttcgcgga ccctgggtct
     9721 ggagacgaag gcagcgcagt caatcagcag gaaggtggca tgtctgcaca acccgtcgat
     9781 atccaaatat ttggccgttc actgcgagtg aattgcccgc ctgaccaaag ggatgcgttg
     9841 aatcaggctg cggacgatct gaatcagcgg ttgcaagatc tgaaagttcg tactagagtc
     9901 acaaatactg agcagttggt tttcattgcc gcattgaata tcagctatga gttaactcag
     9961 gaaaaagcga agacccgcga ttacgcggcg agcatggaac aacgtattcg gatgctacaa
    10021 cagaccatcg aacaggcgtt gcttgatcaa ggtcgcataa ccgaaaaaac gggccaaaac
    10081 tttgaataac acttttcgct ttactatggt aaagtgattg tgaaaacagt atttctctga
    10141 gatgtttgca agcgggccag tcccctgagc cgatatttca taccacaaga atgtggcgct
    10201 ccgcggttgg tgagcatgct cggttcgtcc gagaagcctt aaaactgtga cgacacattc
    10261 accttgaacc aagggttcaa gggttacagc ctgcggcggc atctcggaga ttccccttct
    10321 gactggcgac agccatgacg caacttcccg aactctcttt atcacgacaa gaaatccgcc
    10381 gaatgattcg gcaacgtcgc cgtgcgctga cgccagagca gcaacgccgc tttggtcaac
    10441 aggccgccgc ccgaatgctc agctttcctc ccgtcgtgat ggcgcacact gtcgccgtgt
    10501 ttctctcctt tgatggcgaa ctcgacaccc agccgctgat agaacagcta tggcaagcgg
    10561 gcaagcgcgt ctaccttccg gttcttcatc ccttcagccc tggcaacctc ctgtttctgc
    10621 actatcatcc gcagagtgcg ctggtgacca accgcttaaa tatccgggag ccacggcttg
    10681 atgtccgcga cgtattgccg ctggcaaagc tggatgtgct ggtaacgccg ttagtcgcgt
    10741 ttgacgaagg cgggcagcgt ttaggcatgg gcggcggttt ttatgaccgc acgctacaaa
    10801 actggcagca gcataagatc ctacctgtgg gctacgcgca tgattgccag ttagtagaaa
    10861 aactgccggt tgaagagtgg gatatcccgc tgcctgcggt ggtgacgccg tccaaaattt
    10921 gggagtggta gccgtgtttt gtcgattgac agcgtcgctt ttttgaccta aatttctcgg
    10981 tgaagggtga gggaggcgaa cctccctcct gcgtactcac tgttaatatg ctgggcaagc
    11041 gatgattaac aggatcagca gcatgatgac gtatctcatc atcgtccctt tcctttttag
    11101 agcccctgcc tcggtagggg ctttcccgtt tcagcgctat gctgagccct tatcgtaaat
    11161 tccttttatt gctgtacaac acgcaacgct gcctttaatt accaattgcg gcaaggctcg
    11221 aaaacagaat gtatgcgtta cacgaagaga tgttgaggca gggaaaccag agaaaggatg
    11281 ggcaggtcat ctcctgccca tttagaggaa attagtacag cagacgggcg cgaatggtgc
    11341 ccggaatcgc cttcatcgcc agcagcgctt tctccgccac atcgccatcg gcttctatat
    11401 caattaccac ataccccatt cgggcggagg tttgcagata ctgtgcggca atgttaacgc
    11461 cctgctcggc aaagatctgg ttaagcgcgg tcaatacgcc cgggcggttt tcgtggatgt
    11521 gcatcaggcg acgaccgccg tgcagcggca gcgacacttc cgggaagttc acggcggaca
    11581 gcgtcgagcc gttatccgag tacttaatca gttttcctgc gacttccaga ccgatgtttt
    11641 cttgcgcctc ctgcgtcgag ccgccgatat gcggcgtcag gatcacgtta tcgaattcgc
    11701 acagcggaga ggtaaacgga tcgctattag tggccggttc cgtcgggaag acgtcgatag
    11761 ccgcccccgc cagatgtttc gtcgccagcg cgtcgcacaa agccgggata tccactaccg
    11821 taccgcgcgc ggcgttaatc agcagcgaac ccggcttcat cagggctatc tcttttgcgc
    11881 ccatcatgtt tttggtggag gcgttttcag gtacgtgcag actgaccaca tcgctcatat
    11941 tcagcaattc agacaggtgc tgcacctgag ttgcattacc gagcggcagt ttattttcaa
    12001 tatcatagaa atagatatgc atccccagcg attccgccag aatgcccaac tgcgttccga
    12061 tatggccgta accgataatg ccaagctttt taccgcgtgc ttcgaacgat cccgccgcca
    12121 gtttattcca tacgccgcgg tgcgctttgg cgttcgcttc cggcacgccg cgcagcagca
    12181 gcaatagctc gccaatcacc agctccgcca cggaacgggt attcgagaat ggcgcgttaa
    12241 agaccggaat accgcgtttt gccgccgcat ttaaatccac ctggttggtg ccgatgcaaa
    12301 aacagccaat cgccaccagc ttctctgcgg cgttaatcac ttcttctgtc agatgagtac
    12361 gggatcgcag accgatgaag tgggcatcgc ggatggacgc tttcaactgt tcagcgtcca
    12421 gcgcgccctt gtgatattca atgttggtgt aacctgccgc acgaaggctt tccagcgcct
    12481 tttgatgcac cccttcaacc agcagaaatt taattttatc tttctccagc gatacctttg
    12541 ccatttcccc gatcctgtct ttttttgcca tctgatgttg tgtgtggatt tgcatccgtc
    12601 cttcaacata tcaaaaaaaa ttatcacggc aatatgaacg tttgcgccaa cgccgtgaag
    12661 gaatcgcata cagcgggaaa tagcagatga aaataccggg aataactttt ctttggaggg
    12721 atcggcaggg caaacgatta aacgtgatac atgtcaccaa atttgccctg accgaattct
    12781 ttacgcggca ggaaatacgc ctggcgggat cattttacga tggttttcac cccgtccggc
    12841 gtgccgatca gtgcgacatc ggcgccacgg ttggcgaaca accctacggt cacgacgccc
    12901 ggaatcgcgt taatggcgtt ttccagcgcg atgggatcaa ggatttccat accataaaca
    12961 tccagaatca cgttgccgtt atccgtgacc acgttctgac ggtactccgg acgcccgccc
    13021 agcttcacca gttgacgagc aaccgcgctg cgcgccatcg gaatcacttc gaccggcaac
    13081 gggaatttgc caagaatatc cacctgttta gaggcatccg caatacagat aaatttctcc
    13141 gccacggaag caataatttt ctcacgggtt aatgccgcgc cgccgccttt gatcatctgc
    13201 atatgaccgt tgatttcgtc cgcgccatcg acatagatac ccaggctatc cacttcgttg
    13261 agatcaaaca catgaatacc gaggcctttg agtttttcag tcgaggcgtc cgagctggag
    13321 accgcgcctt caatctggcc tttcattgtg cccagcgcat caataaagtg tgcggccgtt
    13381 gagcctgtac caacgcccac aatggtgccg ggctgtacat actgaagtgc cgcccatcct
    13441 accgcttttt tcagttcatc ctgcgtcata gatcgtttcg cctgtggtgt gaaaatacag
    13501 ccgcattata gaacattgtc gggaaaaatc tccgtgtccg tacacaggct acggatttca
    13561 tctgtaccga cggcaaattt atgtcatagt gcggaaaaaa taacaggagc atgacacaac
    13621 aatgaaacgt ccggactaca gaacactaca ggcgctggat gccgttatac gtgaacgagg
    13681 attcgagcgc gccgcccaga agctgtgcat cacgcaatcc gccgtctcac agcgcataaa
    13741 acagcttgag aatatgttcg gacaaccttt gttggtgcgt accgttcctc ctcgccccac
    13801 ggagcaaggg caaaaattac tggctctgct gcgtcaggtt gaactgctgg aagaagagtg
    13861 gctgggcgat gaacaaaccg gctctacgcc gctactgctg tcgctggcgg ttaacgccga
    13921 cagtctggcg acctggctgc ttccggcgct ggcgccagta ctggcggact cccctatccg
    13981 tctcaattta caggtggaag atgaaacgcg cacgcaagaa cgtctgcgtc gcggcgaggt
    14041 ggtgggcgcg gtgagtattc agcatcaggc gctgcccagt tgcctggtag acaaactggg
    14101 cgcgctcgac tatctgtttg tcgcgtcaaa gccgtttgcc gagcgctatt ttcccaatgg
    14161 cgttacccgg tcgtcgctgc tgaaagcgcc cgccgtcgcg ttcgaccatc tggatgatat
    14221 gcatcaggct tttttgcaac agaatttcga tctaccgccc ggcagcgtgc cgtgccatat
    14281 cgttaattca tccgaagcgt ttgtacagct tgcgcgtcag ggcacggcct gctgcatgat
    14341 ccctcacctg cagattgaga aagagctgga aagcggcgag ttgatcaact taacgcctgg
    14401 cttgctacaa cgccggatgc tttactggca ccgctttgcc ccggaaagcc ggatgatgcg
    14461 caaagtgacc gacgcgctgc tggagtacgg gcacaaggtg ctgcgtcagg attagcctct
    14521 ctatgaatgc cggatggcgg cgtgaacgtc ttatccggcc tgcatgaccc attattcccc
    14581 cgtcgcttct ttgaaattga tcacaaaatc attgcgttca ggcggcaaaa aacgacgcgc
    14641 cattggctat tttttgctgg cggcaaggcg actcaaaacg ctcaccgtat tatcaaatct
    14701 tcatttcatt gcgtaatacg gagcaaaaaa tgagaacacc gggagaaaac gcggcctgga
    14761 agcgcccagg ccgggcgaga ttactgcgtg ctggcggccg ttgtcgacgt ctgccctgtt
    14821 ccaggttcaa gctggaatac cacatcgacc tgatcgtcga actgaatagt cggctgctcg
    14881 taagtttcct gcgcggatac cggcgcagca tctgcggctt tcatcattcg caccaccgga
    14941 ctcggctgat aattagagac atggtaacga acgctgtaaa ccggccccaa tttgctgtta
    15001 aaaccggctg ccagcgcttg cgcctgatga atcgcgtcat caatggcggc tttgcgggcc
    15061 ttgtctttat aggcgtccgg ttgcgccacg cccagcgata ccgaacgaat ctcgttcaga
    15121 cccgccttca gcgcgccgtc cagcagcgaa ttgagtttat ctaactgacg cagcgtcacc
    15181 tcaacggttc gcaccgcgcg ataccctttc agaatgcttt taccgttttg gtaatcataa
    15241 tccggctgcg tgcgcagatt cgccgcgcta atgtcttttt tcgcaatctg attttgctca
    15301 aggaaggaaa gatattgcgc cacgcgctca tcggcctgct tcttcgccgt cgccgcatcc
    15361 ttcgccgcga cgttcacttc aatcgctaag gtggcgatat caggcacagc atcgacgctt
    15421 gctgtaccgg aagtcacgat gtgcgggcct tccggcaatt cgcttgcctg cgccgacatt
    15481 gcacttaaac ccactaatgc cgccagggcc atcactttga acttcacagt ctctcctcca
    15541 tattgcagtc attgccctga tatacagggc gcatgcaggc aagcttagcg gatatcggtc
    15601 tgttgtccat cagacaacgc ttagttgaaa agcgcgtgca tatgcgcgac gccttcccgc
    15661 gccagttgga aggcgataag ccacatcacc acccctacca gaatgttgat aatgcgttga
    15721 gctttcgccg tacgcagtcg aggcgcaagc caggccgcca gtagcgctaa cccaaaaaac
    15781 cataagaacg acgcgctaat cgtgccgaga gcaaaccagc gctttggctc catagccagt
    15841 tgtccgccga gactgcccaa cacgacaaac gtatccagat aaacgtgcgg attcagccag
    15901 gttaccgcca gcatcgtagc aataattttc cagcgcccct gcttcataac ctcggcgctg
    15961 gccagctcca gattactgct cattgccgtt ttcagcgcgc caaaaccgta ccataacaag
    16021 aacgcaaccc cgccccatgt gaccagcgcc agcagccacg gcgactgcat cagcaacgcg
    16081 ctaccgccaa aaataccggc gctaatcagg actaaatcac ttaacgcgca aagcagcgct
    16141 atcatgaggt ggtactggcg acgaattccc tgattcatca caaacgcatt ttgcgggcca
    16201 agcggaagga tcatggcggc gccaagggca accccttgaa aataataaga tatcacgtta
    16261 actaccctga gctgtttttc ttaaaggcag actatagcgc gggaatatta ttagcggaaa
    16321 ttgataattt taatcactaa taagaaaagc taataaagag actgaataac ggatggcggc
    16381 tacgcttatc cgctcaataa ccagagaata ctggaggcgg ataagcgcag cgccggcagg
    16441 cagcacggga ggaaaattac tccgcggcgt tatctttcac gcgtttaaaa ttgacgtcca
    16501 tctgcgggta cgggaagcta ataccagcgg cgtcgaattc acgtttaata cgttccagca
    16561 cgtcccaata gacattttgc aggtcgctgc ttttactcca gacacgcacc acaaaattaa
    16621 ttgatgaggc gcccagctca ttcaaacgca ccgtcatttc gcgatctttt aaaatacgat
    16681 cgtcggactc gataatcgtc gttagcagct gtttcacctg atcgatatcc gaatcgtagg
    16741 ccaccccaat aatgaattcg ttacggcgaa ccggctcacg agaatagttg atgatatttc
    16801 ccgcgataat tttgccattc ggaatcacaa taattttgcc gtctaccgcg cgcattgtcg
    16861 tggaaaagat ttgcacgttc agtaccgtac cggcaacgcc gcccaaatcg acatactcac
    16921 cggcgcggaa cggacggaac ataaccagca ataccccagc cgcaaggtta gaaagcgatc
    16981 cctgtaatgc caggccaacg gctaaaccag cggcgcccag tacggcaata accgaggcgg
    17041 tttgaacccc cacgcgaccc agagccgcaa tcagcgtaaa agcgataacc ccatagcgca
    17101 ccagcgcaga aagaaagtcg gctactgtcg catcaatatg acgcgcacgc atcagacgat
    17161 ttaccgtatt ggagatcacg cgcgctacaa tcaagccgat gatgataata gcgatagccg
    17221 caacaatatt cacagcatag ctgagcaata acgcctggtt gcgtaccagc caggtgcccg
    17281 caccatttat gctgtcgaca acattcaaat cttccattca atattccttg gtcatagcaa
    17341 aacaagcaaa tgagatcatt ctcacgaaaa gaacttttta aaggtaaaca aaaacagagg
    17401 aatatgccat ttttcggcat catcccaaaa aaggcaggta cactgtgagt tggccggatg
    17461 aaagcgctaa ctaacgccgc tctccggaaa taacgataat aaatatcctc cggcatagcc
    17521 ggaggttttt c
//
LOCUS       DAJVKX010000090        17426 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.090, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000090 DAJVKX010000000
VERSION     DAJVKX010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17426
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.090"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(119..220)
                     /locus_tag="OPY25_003096"
                     /pseudo
     CDS             complement(119..220)
                     /locus_tag="OPY25_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(221..7488)
                     /locus_tag="OPY25_003097"
                     /pseudo
     CDS             complement(221..7488)
                     /locus_tag="OPY25_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528616.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7600..13992)
                     /locus_tag="OPY25_003098"
     CDS             complement(7600..13992)
                     /locus_tag="OPY25_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928653.1"
                     /translation="MDRNRQVNKVVHFLLTLLIMFVASIAPAQALLKGGTWQELNSAT
                     AAVNGTVPRADGAIIPVYQGSMLLDPTKTYDVAFTAMPRDFSADATSTSMRAVNSTDT
                     EGDLFSDPPTIAWENQQPPSVGLLWADAATPDTPLSPQPTPNQTFCAQNLAGRKLVVW
                     PQPDDETTVPALWLYTHTGVPNNAAIPLLSPKVTVNIAQAVGNPVSVSGDHVDASFKA
                     SKVKVGESITLTVTTRGCDGKLVKNAPFVIRREDAKNRQGVVNNTNPVHVGDAELTTV
                     QTEYRGVTDAEGKATVVVTQDEGPGVKTHLIVASQSYPTLTDGVDVIFTTITSPDTAQ
                     ANMYGHMLESASATLNGATYTFTRPKLAVEAGNADESVNDTNETWAQFTWSGADNHCD
                     VLPDAEQLVALRHAHSTLATYTGWPASGDAEYWSSTKDQMNNYHAAVHMNSASVVRAP
                     NSDTLLVSCVDKAQPAAHPQITLSPEGPYKAQVGESIDLVMTVVDKDTQKPLPYRYME
                     LFIDPAKNRKGEHQDAWDNQRVTVSSEDMRASSPEHYTGVTDVNGQAHLTLQHDSGMG
                     GETPIRIVMPDDEGGNVELPFSVIFTVITSPDVDGANMWGHMRGVVDAGNLYKRPLLA
                     VEASHKDGQFSENNEEWATFNSVASATAQCGVGQVPDQSSLAHLYSEHPSGKMEIEHG
                     WPTEDYFIAADSDASGTVHVNLANGDSNKFTNQPNYLTCSANEMVAVLDVYFNDDPTT
                     KNADMTAKVGEQIKLNIHSRNALNDMAIAYTDFTITMANGKRRDGLTTGFTDPSNGEM
                     QFDGVGYLAGQVYHGITDANGDATIILTQNKGVGLLTPLSIAPVDSLIKTPISRSVKF
                     TVATSPDTVKAKMWGHMADTLTVGDWTFERPKLASEVNSPLRTQEESNETWTRVAHID
                     AAGNPDAGGCAANRLPRIDQLEALYSANSGGAMKKTQGWPTLINYWSSTYQSATTWKL
                     IALASGSEFPGSNTSVYTSCLASDNPVPAAITIEPVDPSQWYDGSGVHALKVKKGDTL
                     QLKVTVKDASGKPVPEAPFVLTRGDGYDRKGEKYTAQDGSDLQNIVTPVVIDGESLAW
                     TTTKMGSQTGPDGTRIISVTRPDTHGTRTAITATLYENVAVSASIDTIFTVVTSPDVS
                     VARMWGHMTPSLTAADSAVYKRPLLYDELASKTGAAEYPEDNERWVVFYGPNTTKTVS
                     PEACSKGYFPSVEQLDSLYSKYPNGAIKTAQGWPIIRSYWSGTNAGTITPGAPPYDYY
                     TVDLNDDAHRKVPNISDSDRQYQICAATPQPLAGRITLTSTLATDSDIQAVKAKNSDS
                     IPLVITTTDAAGNPVPYTPFSLIRDAGTARNTSYTFTGSTNMMLAPPTGSAQQFYYNG
                     YTIYGATGADGTAVLTLTQAAGPGVKNVITAALTDTPTVTSTLPVVFTTVTSPDSPQA
                     NMYGHMPETFTASNGAEFKRPLLYSELASTLGVKSYADTNENWPIVNNFDTSNYGACS
                     INQMATLDDLKALYGDHPSGKVTTDIGLPVRKKWWAGDSLLQGQVIYWRYIDLSTGID
                     YSMSGTPGNYYYQLCLTKPRQMNIALSTDAWNADKSAAVAKKGETIPMTVKVTNAAGQ
                     PVSNATVKITRGDALTRAGSVYTTNNADDITLSNIQPSGTATYLLGSVDKYMYAQTDA
                     QGQITFSVSQNNTMGLKTPIRVTVANDITATSSKDVIFTVLTSPDVASANYWGHMPET
                     VEGPDGLRYQRPHLQAEAPSGVNYITVNGEKWAAPTGVQTYTAGQSACDVEYMPLMND
                     LKALQQLYPDGALEDQFGWPVKTGKLWWSADLNSSKAHQAINLKTGQISAPTSTSLQA
                     CLVNARNVPASITLTSTAMDAEKGAAVAKKGEAIPLTVTVKNRAGVPIANEPFTLKRG
                     DANDRLDIKYTWNTTADDLTLQELTPSPTTKSMTASGNVFSGVTGADGTATFTVNQDG
                     SVGLKTELTASATGDVTQSTNTALGVIFNVITSPDTDKAQYWGHMPDTLTVGGVTLHR
                     PLLMKEAPAGATDSRKENNETWVSVYTKADGLTYDMSKNCGGVAGFPAKGVLEKIRDE
                     QMAVANGWPTVSLPYASSTPGTYNYCWVSLAKGGTTHCPTTSSDYSIGYAACLVQP"
     gene            complement(14112..15077)
                     /locus_tag="OPY25_003099"
     CDS             complement(14112..15077)
                     /locus_tag="OPY25_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928654.1"
                     /translation="MQATVKRRLTKVALALVVAGYCAAPAVAANGNLKSGQWQIVSEQ
                     TGTIQGTVPWITRAADKTADTDKDHVTVTIDRGDRKIVTEGDKQFHVGDKVTVNWAIG
                     DTEGDLDVDNAATKLTVQWMRYSDQNGSNPEEIGAKGSDTYEIQAGDADHYIGIKITP
                     TTTTGDPAVATELLLKDLSTDAGGGADGDDIPEGPVVDENVHVVIHEKDSNTNLLKNS
                     GTTLKTNTTYQVLLWSDKNGNGTYDAGENVTDQYDYRWKFVGTSKIAGTGTGGIVNEN
                     WNDKDLVIPLTNAEAKEAFEGAEGGVTVGSDGVQGFGLSIDYKRK"
     gene            complement(15135..17327)
                     /gene="sinH"
                     /locus_tag="OPY25_003100"
                     /pseudo
     CDS             complement(15135..17327)
                     /gene="sinH"
                     /locus_tag="OPY25_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like inverse autotransporter SinH"
BASE COUNT         3262 a         5015 c         4882 g         4267 t
ORIGIN      
        1 aaaggtgtga ttatcatgcg acacctggtg ttattttgta tataggtagc gccagatacc
       61 gggttacaga agggaaacgg cgcatctaca caccagcggc aaacggtgat gactccaatt
      121 agcagaacat atacttttca atgaatgctc cgatcacttt ttcatgaagc tcaattgaac
      181 gtgaaaaaca aattattttt cgtgccagac gcttaatacg ttactccacg cacgtcgcat
      241 aacctgctgt acttgccggc tgaatggcgc agttttgctg cttagtattc tcatccacgc
      301 cgcaatacat gccgccgccc gaggttgatt tagataaata gggatagccc agcgtcggcc
      361 agcctaacga gctaattgaa tgatacagcg tcaacaggtc gttattatcc ggtgctttgc
      421 tcaggctacc gcactgttta gcaatatccc atttagtgtt gtccaccgta tgcgtcatcg
      481 cccagtactc gttatttgca tgaactccgt tggtaaatac tggcgtcacg cctgacggta
      541 gctcagcctg cagccacgga cgatgcagcg tttttccgtt gacggatgtc gtatccgaca
      601 tatttcccca gaacaacgct ttatccgtat ccgggctggt aagtaccata aaaatcacat
      661 ccagtgaggc gtgaagagcc gtattgtccg tcagtttcac cgtgagtggc gtttttaacc
      721 ccagactttt atcctgatta agcgtaaacg ttgccgtacc gtcgctgccg gtagtgccgg
      781 taaagacaat cccggtggtg gtcatacttc ggctggcgct tgcgggagtc agctctttaa
      841 gcatgagatc atctgctccg gcatccgctg ccacgtcgcc atccgttacc accgtacctg
      901 cccgattttt cgaatcgcca cgtgacaacg taaaaccgac gttggcgacc gggttaccgc
      961 tgctatcttt taccgtcacc gttaacggca tcgcgcttcc cttctccact accgccgcgt
     1021 ttttcgcgct gtccatcgcc gtcgaggtca gcgtaatatt ggcaggagta gacgtatgcg
     1081 gctcgaccag acacacctgc gcgccagaca cgctcgtgga actggtgtgg cctttggcgc
     1141 cggtatccag ccgcagatac tggtaatacc cggttccagg ctcctggtcc accgccagcc
     1201 agcttttacc cgcccctacc ggccagccga atgccgtatt gagagcgctg tctggatggt
     1261 cgctatacag cgtttgcagg tcattaaaca acggctgata tgcagcatca caggtggtcg
     1321 cgcccgcttt ctgggtgttc gcgatagtca ccagaggcca tgtttcgtta ttgtaatagt
     1381 aggtgccgct attcgacgtc atctccgcag ccagcagcgg gcggtggaat ttcacccccg
     1441 cgctgttggc cgccgtttcc ggcatatggc cccacatttt ggctttatcg ctgtccgggc
     1501 tggtaatgac ggtaaaaatg acatccatat tgctgacggt cggcggattg tcggacagca
     1561 tcgcctgcag cgctgttttc aggccggggg tattatcctg cgtcagctca aactgcaccc
     1621 tgccgctctc atccgtagtg ccgtaccagt accagagctg ctccccggaa taatggtagg
     1681 caaatacttt agcatccgct ggcggcgcaa tcggcgttaa cagcatgtcg ctgttgttgg
     1741 tgctgtcact accgccagcc cggttttgcg aatagtttcc tcgccccagc cgaatgggca
     1801 cattgggcta cggcgtgccg gcgccgtccg tgacggtcac cgtcagcggg attttatccc
     1861 cttttttcgc cagcgcggcg gatttttcgg cattcatggc gctggaggtc aacgctatcg
     1921 ccaacaccct gcgcttcgcc agacagagct gcgccgttga ggtattcgta tttgtgacct
     1981 gcgtaacgcc gttatttagc ctgatatact ggaaattatt cgtcgagtgc gtatcgttga
     2041 ctttcgaatc ccctgctccc cagtatttcc ccgcgtctac aggcaaccca aaggcggccg
     2101 ttagtccacc attcggatag tcgttataca acgtttttaa atcatccagc gtcggcaatc
     2161 ccagccgatc gcacgggctg gcggagtcct gatacaggtt tggatagcgg ttccaggtgt
     2221 accagtgctc attatttgac aggaaggacg tggtatccgt cgttgaagaa agctcggcgc
     2281 gcagcagcgg ccgcgcaaac tcaacgccct tactgttggt aaaggtttcc ggcatatggc
     2341 cccagtatga ggccttgtcg ctatccgggc tggtgataac ggtaaagata gcgtctttgc
     2401 tgtctgtcag gttgctgccg tccatcgtgg cggcgctgat ggtggtcttt aaacctgcgg
     2461 tactgtcctg cgcaagggta aatgtcacct gtccctgggc atcggtttgc gcatacagat
     2521 atttcgcgga ggtatccagc aggtatgtcg ccgggccgga cggcatcaca ttacgcagcg
     2581 taatatcgtc tgcagcgctt gaggacgatg tggcgctgtt gacgcggttg tacgaagatc
     2641 cccggctgat tttcaccatc acgtttttca tcggctgacc tgcggcgtct ttcaccgtga
     2701 cggtggcggc catctgctcg ccctttttcg cttttgcgat cccggtggct gcatcctggc
     2761 ctgccagcgt cagcgtcagg ctggcggcgg cgctgcgtgg cgaggtaagg caggtctgca
     2821 tatagtacgt cgtggtgctg gtcgtcgttt tgacatcatt gccgtcgtta aacaggttga
     2881 ccgccgcgta gagcgactgc gcgccgtctg acgacatcac gtaatccccc gcccaccagt
     2941 agcggctgac gttattgttg ccagaactgg tcatcggcca gccgttacaa ctgcgcatgg
     3001 cgttatcagg ccaggtactg tacagcgtct ggaggttgct gacggtgggc agataattgc
     3061 gcccgcagcc gccgccggcg ccgttctagg ctttatcgac ggttatcatg ccccaggttt
     3121 cgcctttgtc gtagtaaccg ttggcgatgg tcagcgattt gccgggcgtg acgctgaact
     3181 cgctggccag caacgggcgc ttgtacacca cgccgctgct gtcggtcagc gtttccgcca
     3241 tatggcccca gtagttggct ttcggcgtgt ccgggctggt gacgacggta aaaatgaccg
     3301 gtagcagcgc gctcgttacg ccgttgtgct ctatcaccgc cgtcagcggc gttttaaagc
     3361 ccgcgccgct gtcctggctg atattcagcg tcagcgtgcc gtcagcgccg gtggcggtgt
     3421 aatatttaac gccgctgcta cgcccgtcgc tgtggtttat ctgtatctcc gccgccgacg
     3481 cgctattcac ttcctgattc gcgcgcccga cgctgtcgcc gcgcgtaaag ataaccggcg
     3541 tgtcggcggc caggttgccc tgggcgtccc gcgtggtgat gatgaccggg atggtctcgc
     3601 cgactttcgc tttggcaaat ccgtcgctgt cgttatacaa aggcgaagtg agcgttatct
     3661 gcgtcgccgc cggatgggcg ttttgcaagc agacgaaata gagttgttca ctccacgcca
     3721 gcgagctaat accgccatcg cgcagatcaa tcgacttaac gtagcggttt tccgtactcc
     3781 tgctcaaatc agcggtgctg ttctggtagt ttttaccatc cagcggccag ccctgctgcg
     3841 tattcatggt gccgccgggc ctggcgtcgt acagcgattg cagatcggca agtgtcggta
     3901 cgtatcccgc gccacaggcg tcgttcgcca cttcaaaatc gacgattccc caggcttcgt
     3961 tgttttccgt attgtcgccg tgggtaaagc cgctggcgat ttcagccgat aacagcgggc
     4021 gcttaaacac cacgccgttg gccgccgtgg tcgtttccgg catatggccc cacattttgg
     4081 ctttgtcgct attagggctg gtgaccacag taaaaatagt gtcgatgctg gccgtcgcgc
     4141 tggcgttatc gtacagcgcc gccgtaatcg cgactttcgt cccgtgggca tccgggcggg
     4201 tgacgttgat gattttgctg ccgttttcac cggtcatgcc gccgattttg gtggcggtgt
     4261 cgttgagcga atcgccgtca atcactaccg ccgagacgat gccgtcgccg cggctgagca
     4321 cgaacggcgc ttgcggcagc ggattgccgc tggcgtcttt taccgtcact ttaagctgga
     4381 gcgtatctcc ctttttcacc ttcaccgcgt gttcgctgtt ctcgtcatac cacaatgacg
     4441 tattcaccgg ctcaatggtg atggaggctg ccgtcgggtt atcgctggca aggcaactga
     4501 cgtaatcgga tgcgccagcg ccgcccggaa attcgctacc gttagaaagc gctatcagtt
     4561 tccacgttgt ggcgctttgc caggtggagg tccagtaatt aatcagcacc ggccagccgt
     4621 gcgtgctatt gatagccccg tcgcggttag cggcgtaaag cgcctccagt tgatcggcgc
     4681 gcggcaatcg gttagcggcg cagccgcccg ccgccgtatt gcctaccgca tcggcatggg
     4741 tagcgcgcgc ccagctctcg ttggcctcgg tttgggtgcg ggtcgcggca acctccgccg
     4801 ccagtttcgg tcgctcaaag gtcatatcgc ccaccgtgat ggcgtcggac atatggcccc
     4861 acatttgcgc atccggcgta tcggggctgg tgggaacggt aaacttcacg ctgcggttaa
     4921 cgggggtggt gatcagcgag ttaaccggca gtacggtcag cggcgtcagc aagccgacac
     4981 cctgcggttg ttcaatgacc agcgtggcgt tgcctgcggc atcggtcatg ccctggtacg
     5041 tcatcgacgc cagggaagag ccgaaagacg ttccgcccat caccagcgtt ccgtcgctgg
     5101 gatcggtaaa gcccgtggtg gcgttggcgc gatttttacc gtgcgacatg gtgacggtaa
     5161 agctggcgtt gggcacgctt aacccgttca gcgcgttgac ggaatggacg ttcatcgtaa
     5221 ttttttcgcc cactttggct accgcattac gtaacgactc gttgccatca aagtacacgt
     5281 ccaggctggt caccaactcg ttaccggagc aggagagata gttcggttca gcgccgctga
     5341 acaggctgtc cgcgccggtc gccaggttaa cgtgcgcagt ggtggaacca tcggtatccg
     5401 ccgcaatata gctatgtttc tgtgtcggcc agccgtaagt cgtttccatc gtattgccgg
     5461 aatgggcttc atacagcgta tccagcagca gttgtcccgg cacctggcct gcgccgcact
     5521 ggtttgtcgc tgccgtcact gagttaaacg tggcccagta ctcgttattc tcaaattcgg
     5581 aaccggtatc ctgcgcggcc tcttccgcca gcagcggacg tttgtaaata ttgcccgctt
     5641 ccaccacgcc ctgcatatgg ccccacatac gggcctgcgt cacgtccggg ctggtgacga
     5701 cggtaaaaat cacattctgc gtcgcttccg tgccgtcgaa cagcaccacg cgcaccgggg
     5761 ttaatacgcc agcgcccttg tcctgggtca gcgccagcga aaactggccg ttggcgtcgg
     5821 tgacgccgtg atagtgaccg tcgccgccgt ccagattggc gataactacc ggttcatccg
     5881 tccactgatg cgcggcatca agatcggcgt tcttctgatt ctggcgattt tgctcgtcgc
     5941 ccaggtagac attaaagtag cgataaggca gcggtttatt ggtggcgctg tcggtgacgg
     6001 cgatcttcat gttgatctct tcgcccacct tcactttcgc cgcgttggcc gtcgaatcaa
     6061 aattatcggt gctaatcact aatttcggcg tgaccgcagg cgaggcttta tccacacagc
     6121 tcaccagcga ttgcgtggcg tccggcatct gcgtaagggc gcggctgcgc atatcaatgc
     6181 tgatgtggtc agttgcgctc gccccctgtg aggaggacca gtgctcttcg tcaccggatg
     6241 tcaccccacc ggccagccga gagtggtggc taaatcgccg cgctcgattt ttaacccttc
     6301 cagttggcgc gcatccggca gaatatcgca gtgtttatcc gcatggcccc aggtgaactg
     6361 cgcccagttt tcattattga tactggcgac gcggtcttcg ccctcggttt ccgccgccag
     6421 tttggggcgg tcaaaagtgt agcttgcgcc gtccaccgtg gcggtggaac tgtccgccat
     6481 atggccgtac atgttggcgc tgctgctgtc cgggctggtg agggtggtaa aaatcacatc
     6541 cgcgctggct ttcagcgcag gcgcgttcga cgggtgcgcc atcagcgggg ttttaacgcc
     6601 cggcccgtta gcctgggtga cggtcaccgt cgccacccct tccgcgttgg tcgtgccgtg
     6661 gtattcggtg gcagtggtgg tgagttcggt gttgccgacg cgtaccggcg cggtattgtt
     6721 caccacgccc tggcggtttt gcgcatcgcc gcgggtaatc acaaacgcga tattgcccgc
     6781 tggctcaccg ttacaacctt tggtattcac cgtcagcgtg atgctttcgc ccgctttcac
     6841 cttcgcggcg ttaagcgact catccagatg atcggcggta agggttaccg ggtcacccac
     6901 ggcgggcgcg atatccacgg caaacttttg ttcaagcact tcgaccgccg tgttataagg
     6961 cacgccggtg cgggtaagca accacagcgg cggcatagcg gttgaggtat ccagttgcga
     7021 ccagactacc agatggcggc ctgccatatt ttgctcacag aacgtcaggt ttgccgacga
     7081 ttgtggagac agcggcgtct ccggcgtggc ggcgtcggcc cataccagcg tgacggaggg
     7141 tatccgttca ctctgccaga ccagcggcgg ctcggcgaaa atatcgcctt cggcatcgcg
     7201 cggattggtt aaggtcagcg cgctgccgac atcactggtg ctgaactggc tgggtttcgc
     7261 ggaataatcg acgggattcg ctgcatcaga tcgcaactga acgctgccct gataaaccgg
     7321 gatcgtcacg ccgtcagcca gcggcggcgt gccgttaatg gcggcagttg agacgtcagg
     7381 ctcctgccat ggggcgctgc tttgcgccgc ctgggcaaaa aaagcggtaa cacaaaacag
     7441 acatgcctgt agcccggata aaagatgggt attcgttttc agtttcaatg cagcacctgg
     7501 aatacatccc tttctgacta ttcattccat cggcggtaaa aatgcgaaac gtttcactac
     7561 cggtaccaac gacaatttac cgaaacccaa ccatcccgat cacggctgta caagacaggc
     7621 ggcatagcct atcgagtaat cgctgctggt ggtcgggcaa tgtgttgtgc cccctttcgc
     7681 taacgaaacc cagcaataat tatacgtccc aggcgtactg ctagcgtaag gcaacgaaac
     7741 tgtcggccat ccgttagcga ccgccatctg ctcatcgcgt attttttcca gcacgccttt
     7801 tgccgggaac ccggccaccc cgccacagtt cttgctcata tcataggtaa gaccatcggc
     7861 tttcgtataa accgaaaccc aggtttcgtt attttctttc cggctatccg tcgcgccagc
     7921 aggcgcttct ttcatcaaca aggggcgatg cagcgtcacg ccaccaaccg tcagcgtatc
     7981 cggcatatgc ccccagtact gcgctttatc ggtatccggg ctggtaatca cgttaaagat
     8041 cacgcccagc gctgtgttgg ttgattgcgt gacatccccc gtcgcgctgg ccgtcagctc
     8101 ggtttttagc cccacactgc cgtcctggtt caccgtaaac gttgccgtcc cgtcagcccc
     8161 cgtgacgccg ctaaacacat tgccggaagc cgtcattgat ttcgttgtcg gcgacggcgt
     8221 cagttcctgc aacgtcaaat cgtctgctgt agtattccac gtatatttaa tgtcgaggcg
     8281 atcattcgca tcgccccgtt tcagggtaaa cggttcattc gctatgggaa cgcccgcgcg
     8341 gtttttcacc gtcaccgtca agggaatagc ctcgcctttt ttcgccaccg ccgcgccttt
     8401 ctccgcatcc atcgccgtcg aggttagcgt aatggaggca gggacattac gcgcattgac
     8461 caaacaggcc tgcaagctgg tggaggttgg cgccgatatc tgaccggttt tcaggtttat
     8521 cgcctggtgt gctttcgagc tattcagatc ggcagaccac cagagtttac cggttttcac
     8581 cggccagccg aattgatcct ccagcgcgcc gtcaggatac agttgctgta gcgcctttaa
     8641 gtcattcatc agcggcatat actcaacgtc gcacgcagac tggcctgccg tatacgtctg
     8701 tacgccggtc ggcgccgccc atttttcacc gttcacggtg atgtagttga cgcccgacgg
     8761 cgcttccgcc tgcaaatgcg ggcgctggta gcggaggccg tccggccctt ccacggtttc
     8821 cggcatatgc ccccagtagt tggcgctggc gacgtccggg ctggtaagga cggtaaatat
     8881 cacgtcctta ctgctcgttg cggtaatgtc attcgcaacg gtgacgcgga tgggcgtttt
     8941 aagacccata gtattatttt gcgacacgct aaacgttatt tgcccctggg cgtccgtttg
     9001 cgcatacata tatttatcca ccgaccccag caagtacgtc gccgtaccgg aaggctggat
     9061 attacttaag gtaatatcgt ccgcgttgtt ggtggtatac acgctccccg cacgcgtcag
     9121 cgcatcgccg cgcgtgattt tcaccgtcgc gttgctaaca ggctgcccgg cagcgttcgt
     9181 caccttcacc gtcatgggga tcgtttcgcc ttttttcgcc acggccgccg atttgtccgc
     9241 gttccaggcg tccgtagaga gcgcgatatt catctggcgc ggtttggtca ggcagagctg
     9301 gtaatagtaa ttacccggcg ttcccgacat ggagtaatct atgcccgtac tgagatcgat
     9361 atatcgccag tatatgactt gaccttgcag caggctgtcg cccgcccacc atttcttcct
     9421 gacgggtaag cctatgtcgg tcgtgacctt gccgctgggg tgatcgccgt acagcgcctt
     9481 gagatcatcc agcgtggcca tctgatttat cgaacaggcg ccataattac tggtatcaaa
     9541 attattcact ataggccagt tttcatttgt gtcggcatag ctcttcacac ctaacgtcga
     9601 cgccagctcg ctatacagca gcgggcgctt aaactccgcg ccgttgctgg cggtgaaggt
     9661 ttccggcata tggccataca tattggcctg cgggctgtcc gggctggtca cggtggtgaa
     9721 caccaccggc agcgtcgagg ttaccgtcgg cgtgtcggtc agggctgcgg ttatcacgtt
     9781 tttcaccccc ggccctgcgg cctgcgtcag cgtgaggacc gccgtgccgt ccgcgccggt
     9841 ggcaccgtaa atagtgtagc cattatagta gaactgttgc gccgaaccgg tgggcggcgc
     9901 cagcatcatg ttagtgctgc cggtaaaggt atagctggtg ttgcgcgccg tcccggcgtc
     9961 gcgtatgagg gaaaatggcg tataaggcac cgggttgccc gccgcatcgg tggtggtgat
    10021 caccagcgga atcgagtcgc tgttttttgc cttcaccgcc tggatatcgc tatccgtcgc
    10081 cagcgtagaa gtgagggtaa tccgcccggc cagaggctgc ggcgtcgcgg cgcaaatctg
    10141 gtattgcctg tcgctatcac taatattggg aaccttccgg tgcgcatcat cattcagatc
    10201 gaccgtgtaa tagtcatagg gtggcgcgcc gggggtgatt gtcccggcgt ttgtgccgct
    10261 ccagtaagaa cggatgatcg gccagccctg ggcggttttt atcgctccgt tcgggtattt
    10321 gctgtacaga gaatccagtt gctcaacgga cgggaaatac cccttggagc aagcttccgg
    10381 actaacggtt ttggtcgtat tcggcccata gaacaccacc cagcgttcgt tgtcttccgg
    10441 gtactccgca gcaccggtct tgctggccag ttcatcgtag agcagcgggc gcttgtacac
    10501 cgcgctatcc gcagccgtca gcgacggcgt catatgcccc cacatgcggg cgacgctgac
    10561 atccgggctg gtgacgacgg taaagatggt gtcgatgctg gcgctcacgg cgacattttc
    10621 atacagcgtg gcggtaatgg ccgtgcgggt gccgtgggtg tccgggcggg tgacgctgat
    10681 gatgcgggtg ccatcagggc cggtctgcga ccccattttg gtggtagtcc aggccagcga
    10741 ttcgccgtcg atcaccacgg gcgtcacgat attttgcaaa tcggagccgt cctgggcggt
    10801 gtacttttcc cctttgcgat cgtagccgtc gccgcgggtg agcacaaacg gcgcttccgg
    10861 caccggtttg ccgctggcgt ccttcaccgt caccttcaac tgtagggtat cgcccttttt
    10921 cactttcagc gcatggacgc cactgccgtc gtaccactgc gacggatcga ccggttcaat
    10981 ggtgatggcg gctggcaccg ggttatcgct ggccagacaa ctggtgtaaa ccgaggtgtt
    11041 gctgcccgga aattcactgc cgctcgccag cgcgatcagt ttccaggtgg tggcgctctg
    11101 gtaggtggac gaccagtagt taattaaggt tggccagccc tgagtctttt tcatcgcgcc
    11161 gccgctgttg gcgctgtata acgcctcaag ctggtcgata cgcggcaggc ggttcgccgc
    11221 gcagccgccc gcatccgggt tgcccgccgc gtcgatatgg gccacgcgcg tccaggtttc
    11281 attgctctct tcctgagtac gcagcgggct atttacttca ctcgcaagct taggccgctc
    11341 aaaagtccag tcgccgacgg taagagtgtc ggccatgtgg ccccacattt tggcttttac
    11401 cgtgtccggg ctggtggcga cggtaaactt gacgctgcgg gaaatcggcg tcttgattaa
    11461 tgaatcgacg ggcgcgatgc ttaacggcgt cagtagcccc acgcccttat tctgggtgag
    11521 gataatggtc gcatcgccgt tggcgtcggt gatcccgtga taaacctgcc cggcaaggta
    11581 gcccacgccg tcaaactgca tctcgccgtt gctgggatcg gtaaagccgg tcgtcaatcc
    11641 gtcgcgccgc ttgccgttcg ccatggtgat ggtgaagtcg gtataggcaa tcgccatgtc
    11701 gttaagggcg ttgcgcgaat gaatattcag cttaatctgt tcgccgactt tggcggtcat
    11761 atcagcattt ttagtcgttg ggtcgtcgtt gaagtagacg tccagcaccg ccaccatttc
    11821 attggccgag caggtcaggt agttcggctg attggtaaat ttgttgctgt cgccgtttgc
    11881 caggttgacg tgtaccgttc ccgaggcgtc gctatccgcg gcgatgaagt agtcttcggt
    11941 cggccagccg tgttcgattt ccatcttgcc gctggggtgc tcgctgtata aatgcgccag
    12001 cgatgactga tccggcacct ggccgacgcc gcactgcgcg gtggccgacg ccacggagtt
    12061 aaacgtcgcc cactcttcgt tgttttcgct gaactgaccg tctttatggc tggcttccac
    12121 cgccagcagc gggcgtttat acaggttgcc ggcatccacc acgccgcgca tatggcccca
    12181 catgttggcg ccgtccacat ccgggctggt tattacggtg aaaatgacgc taaagggcag
    12241 ctcgacgttg ccgccttcat cgtccggcat cacgatgcgg atgggcgtct cgccccccat
    12301 gccgctgtcg tgctgtagcg tcaggtgcgc ctgaccgttg acgtcggtca cgccggtata
    12361 gtgttccggc gaagaggcgc gcatatcttc ggagctgacg gtaacccgct ggttatccca
    12421 cgcgtcctga tgctcccctt tgcggttttt cgccgggtcg ataaacagct ccatgtaacg
    12481 gtaaggcagc ggtttttgcg tgtctttatc gactaccgtc atgaccagat caatcgattc
    12541 ccccacctgc gccttataag gcccctccgg agagagggta atctgcgggt gcgccgcagg
    12601 ctgggcttta tccacacagc taaccagcag cgtatcgctg ttgggcgctc tgacgaccga
    12661 cgcgctgttc atatgcacgg cagcgtggta gttgttcatc tgatctttgg ttgacgacca
    12721 gtattccgca tcgcccgacg ccggccagcc ggtgtacgtt gccagcgtac tatgcgcatg
    12781 tcttagcgcc accagttgtt cggcgtccgg cagaacgtcg caatggttat ccgcgccgct
    12841 ccaggtaaac tgcgcccagg tttcgttagt atcgttgacg ctttcgtcag cgttacccgc
    12901 ctccaccgcc agcttcggtc gagtgaaagt gtaggtcgcg ccgttcagcg tggcgctggc
    12961 gctctccagc atgtggccgt acatgttggc ctgggcggtg tcggggctgg tgatggtggt
    13021 gaaaataacg tccacgccgt ccgtcagcgt aggataactt tgcgaagcga cgataagatg
    13081 cgtttttacg ccggggcctt catcctgcgt caccaccaca gtggctttac cctcggcatc
    13141 ggtgacgccg cgatactccg tttgcacggt cgttagctcg gcatcgccaa cgtgcaccgg
    13201 gttagtgtta ttgaccacac cctgacggtt tttggcatcc tcacggcgga tgacaaacgg
    13261 cgcatttttc accagtttgc catcacaccc tctggtcgtg acggtgaggg tgatgctctc
    13321 tcctactttc acttttgagg ctttaaagct ggcatcaaca tgatcgccgc tgaccgacac
    13381 gggattgcct actgcctggg caatattgac agtcactttc gggctgagca gcgggatggc
    13441 cgcattattc ggcacgccgg tgtgagtata gagccacagc gcggggacgg tcgtttcatc
    13501 gtctggctgc ggccagacaa ccagtttccg tccggccagg ttctgggcgc aaaaggtctg
    13561 gttaggcgtc ggctgcggcg aaagcggcgt gtcgggcgtg gcggcatcgg cccataacag
    13621 gcccacgctc ggcggctgtt gattttccca ggcaatggtc ggcggatcgc taaagagatc
    13681 gccttcggta tcggtggaat tgaccgcacg catcgaggtt gaggtggcat ccgcgctaaa
    13741 atcgcgcggc atggcggtaa acgcaacatc gtaggttttg gtcgggtcaa gcagcatact
    13801 tccctgatac acgggaataa tcgcgccgtc ggcgcggggc acggtgccgt taactgcggc
    13861 agtggctgag ttcaattctt gccaggtccc gcctttcagt aaggcctgcg caggcgcgat
    13921 cgacgctaca aacatgatca gtaatgtcag taagaaatgt acaactttat tcacttgccg
    13981 attcctgtcc atgagcgata gccacccgtt ttcattctct gtcgtaattc aacccacttt
    14041 gcttagcgcg cggctaagca aagtgcgcgg aaaataccac tccccgcggg gagtggtatg
    14101 ttgaggacaa cttatttgcg tttgtagtcg atggacagac caaagccctg gacaccgtcg
    14161 ctacccacgg taacgccgcc ttccgcaccc tcgaacgcct ctttcgcttc ggcgttggta
    14221 agcgggatga caaggtcttt atcgttccag ttttcgttga cgataccacc agtaccggta
    14281 cctgcaattt tactggtgcc gacgaatttc cagcggtagt catactggtc ggtaacgttt
    14341 tcaccggcat cataggtgcc gttgccgttc ttatcgctcc acagcaatac ctgataggta
    14401 gtattcgttt tgagtgtcgt ccctgaattc ttcaacaggt tggtattcga atctttctca
    14461 tgaataacca catggacgtt ttcatccacc accggacctt ccggaatgtc gtcgccatcc
    14521 gcaccaccgc ccgcatcggt cgacaggtct ttcaacagca gttcggttgc cacggcaggg
    14581 tcaccggtgg tggtggttgg cgtgattttg ataccgatat aatggtctgc gtcacccgcc
    14641 tgaatttcat aggtatcgct gcctttggcg ccaatctctt cgggattgct accattctgg
    14701 tcgctgtatc tcatccactg caccgtcagt ttcgtggcgg cgttgtcgac atccaggtcg
    14761 ccttccgtat cgccaatcgc ccagttgacc gtgaccttat cgccaacgtg gaactgctta
    14821 tcgccttcgg tcacaatttt acgatcgccg cgatcgatag ttaccgttac gtgatctttg
    14881 tcggtatccg cggtcttatc cgccgcacgg gtaatccacg gcaccgtacc ctgaatggtg
    14941 cccgtctgtt cagagacaat ctgccactgc cccgatttca gattaccgtt tgccgccacc
    15001 gctggcgcgg cgcaataccc ggcaactact aatgctaaag cgaccttcgt cagccgccgt
    15061 tttactgttg cttgcattca gactctcttt tttctcaaaa ttcagcggct ggctggtcag
    15121 ccataacgct gacgctattt ctgactatac gtaacgcgta taccgtaacc ctgaacgcca
    15181 tcttccacat tggcggcaaa cttctgcgcc gcctctttat tggttactgg cagaacaaga
    15241 tcttcattta tggtgttggc cagcgcgccg gtatgtccgt ttgtactctg tccggtaaac
    15301 tcccactggt agtcgtacag ggccatctct tcttccgtga gctgctcgga catctggaat
    15361 acgccgtctt tattcttgtc gcgccacagc aggaaacggt aggtgttatt aaccgtagga
    15421 tgtttatctt ctttgccgat caggttgaca gggttggcgg ctttgacctg ataaatcacc
    15481 gcattcagcg cgctcaggtt gtcgccgata aaagtgacat caacgtagtt actgtcgcca
    15541 taggcgtctt ctttcgcctt ccagcggaaa gtgcccggca gggtgctgga aagcgtcacc
    15601 gtccccgctt ctttgtcacg gctggcaata aacacgcagg gggtttccgt ggtgcagggc
    15661 gtctgggcca gcgtgacttt tttatcattg ctgtcgtaca acacgggcgt catagcatcg
    15721 tccaccagtt cgttaccatt gcgatccgtg gagtcgccaa aggagtcggt gatcaggaga
    15781 tccatcacca cgccgtcttc gccatcggcc agcgcgctgg cttcatggct gtgatcgctg
    15841 cgatcgttat cggcaatgtt gtcgacgatc agctcaattt tgcgatcctg ctggacggtg
    15901 atttccacca cgccggagtt ctgcttattg cccttttcgt cttccagcgt catgcgtact
    15961 ttccaggtgt tcagggcggt gcgctgcgcc tcggtatcgg cgttaaccca ggcaggaagc
    16021 accagattcc agctgttatt gttgccttcg gtcagcgcat ccgcttttac caccggcatc
    16081 accagagtac gggcggcgtt gtttttcgcc tgccaggaag cagaaataat tttgtaatga
    16141 tggttaatca gcgcgttgac cgtccactta catttctcca gccccaccgc ggcctcaggc
    16201 gtatcttcaa tcacgcattc cgggtgttcg ttggtggcgt cggccttcag ccacaacgtg
    16261 acgtccagcg gatctttctc gcggtattcg agaatgatga aattgttacg atcgacaaaa
    16321 tcggtgcggc tgcccattaa agagtgctgg attttaacgt tttccggatc gagttgcgcc
    16381 gccagcggcg ttcctatctg gtagttcaca gtcactttaa cgctaaaatc gttattatcg
    16441 ccagtaccgg ctttgtaatc cgaaccaacc gtaaccagcg gtaccggcgt atattccagc
    16501 cccaaggtaa cggcatgagg atctttttgc agattatcgg tgccaaacag cgccacttca
    16561 tcgccgtagt actgttcgta aactaattta gcgccaagct gcggataaaa gggcagccag
    16621 ctttccatgc ggatatccca accgcgcgcg ggtcgttctt cataaaagtc gaaatcttcg
    16681 gaatccttcc agtcagaaag aggatggtaa tagttgccgg agaatttcag gtaatccgtc
    16741 caggcttcgg ttcccagacc tagtcgacgg tgaccgcgcg taaaatcgta gtcatagaat
    16801 gcgttgccgc caagcagcca gttgccgacg ttctggcgca cgccaagccc aaagttacca
    16861 atagtgcggt cttctttacg ttgggctgag agttggctaa aaagtaaggt tttttcgtta
    16921 tcataccagg gaacgaaata atccagcgaa ctgccgtcca gatcgccgcc ttcgcctacg
    16981 gagaggctgg tacggatctt gccataaggt gacattacgc cttcaagata tgactgtgct
    17041 gatgaagtga tttggttttg caaatagcta cgcgcctagg attccagcgc ttccggggtg
    17101 agattatcaa agccctgggt ggcggaatta ataaagtagt cagcgccctg ttctttaaag
    17161 gactttcctt tattttcctg ttcttctttt ttcgcggatt cgctggctaa atcaggcagg
    17221 gaggagtggc tttcatcgtt tgcaggtaca gagttacctg cgccggaagc cgcaactgat
    17281 actccagaca ctaatagcaa aaccagaatg cgaatccttc gcaccatatg atatccctgt
    17341 tgttaaataa acacgctgct atgagacgat attatatgga tgattcatag ggaatcataa
    17401 ctaacaggcc taaatatatt cctaaa
//
LOCUS       DAJVKX010000091        17287 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.091, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000091 DAJVKX010000000
VERSION     DAJVKX010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17287
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.091"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..256)
                     /locus_tag="OPY25_003101"
     CDS             complement(<1..256)
                     /locus_tag="OPY25_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HCS0928655.1"
                     /translation="MQRKKILIVGAGLSGAVIARQLAEQGHVVNIIDQRSHIGSNAYD
                     ARDEHTGIMVYVYGPHIFHTDNETVWNYVNKYAEMMPYINK"
     gene            complement(542..1282)
                     /locus_tag="OPY25_003102"
     CDS             complement(542..1282)
                     /locus_tag="OPY25_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein"
                     /protein_id="HCS0928656.1"
                     /translation="MQTLTRVLPPLRLIMFCQSGENPTQFPDTGGLCVEDCVRLRTPE
                     GLLDRLRRWPGAMVISAGRPSTQLLLWQQVFLRYPRTVVFCSSNAFLPVDVSVEGYFR
                     HLRLIKRAMSVRVLARMAELAIWSSLQTSPYEEEMKSALSVPELVMEINSRTLVRLLS
                     ERLPKQGRRVLGLLLSGCSPEMTARMLGTGVRQVWLAEQTLKQRWDIPTGVPLSDAVR
                     IRIPDVGPDISQQSGLVKTGAGNAPDLC"
     gene            complement(1284..1619)
                     /locus_tag="OPY25_003103"
     CDS             complement(1284..1619)
                     /locus_tag="OPY25_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928657.1"
                     /translation="MQPKSRTGQGVREQCLDGARRHFSYRHGMAPGPRKGADMLFPQH
                     EAAVAGAVPGRQWPEENNLMTQEYAEMSTGRGGTSKCRYSMGAKIFLLLLAVSTVAAL
                     FSLYQVLTY"
     gene            complement(1797..2363)
                     /locus_tag="OPY25_003104"
     CDS             complement(1797..2363)
                     /locus_tag="OPY25_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCS0928658.1"
                     /translation="MKRKYLTQEEIEKLLSATDRMPFPERNRCLILMAFIHGFRASEL
                     LGLRLSDIDLAGRQLYIRRLKNGFSTCHPLLPDEYNVLKSWLRARKYLEKGADGDWLF
                     LSLRRHPLSRQQFFYILREAGRLAELTIAPHPHMLRHACGYALADKGIDTRLIQDYLG
                     HRNIQHTVRYTASNAGRFHGIWRKKRRV"
     gene            complement(2423..2554)
                     /locus_tag="OPY25_003105"
     CDS             complement(2423..2554)
                     /locus_tag="OPY25_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928659.1"
                     /translation="MTTYQEIEARLIRCFTITSWIACQIASYMDFKLFTHSNFFSEN"
     gene            complement(2878..3612)
                     /gene="pxpA"
                     /locus_tag="OPY25_003106"
     CDS             complement(2878..3612)
                     /gene="pxpA"
                     /locus_tag="OPY25_003106"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HCS0928660.1"
                     /translation="MNIDLNADLGEGCASDSELLTLVSSANIACGFHAGDAQTMLTCV
                     REALKNGVAIGAHPSFPDRDNFGRTAMVLPPETVYAQTLYQIGALGAIVQAQGGVMRH
                     VKPHGMLYNQAAKDPHLAQAIAKAVHDYDPSLILVGLAGSELIRAGERHRLVTRQEVF
                     ADRGYQADGSLVPRMQPGALIHDEEQALAQTLDMVQAGRVKSVTGVWTTVTAQTVCIH
                     GDGEYALAFARRLRAAFNARNVHVIA"
     gene            complement(3602..4534)
                     /locus_tag="OPY25_003107"
     CDS             complement(3602..4534)
                     /locus_tag="OPY25_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HCS0928661.1"
                     /translation="MLNIIRAGIYTSVQDSGRHGFRQSGLSHCGALDKPAFQTANLLV
                     GNDANAPALEITLGQLVVEFENETWFALTGAGCEAQLDDQPVWTGWRLPVKAGQRLTL
                     HRPLHGMRSYLAVAGGIAVPEVMGSCSTDLKSGIGGLEGRLLKDGDRLATGKPSRQLS
                     GPQGVKQLLWGNRIRALPGPEYREFDRASQEAFWRSPWQLSPQSNRMGYRLQGQSLTR
                     TTDRELLSHGLLPGVVQVPYNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLEQ
                     PIHFVQCSLEEALNARRERRRYLEQLTWRLQHEH"
     gene            complement(4528..5184)
                     /gene="pxpB"
                     /locus_tag="OPY25_003108"
     CDS             complement(4528..5184)
                     /gene="pxpB"
                     /locus_tag="OPY25_003108"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HCS0928662.1"
                     /translation="MQRARCYLLGETAVVLELEPPITLASQKRIWRLTQRLVDMPNVV
                     EAIPGMNNITVILREPQTLALDAIERLQRWWEESEALEPDSRSVEIPVIYGGAGGPDL
                     AAVARHSGLSEKQVVELHASVEYVVWFLGFQPGFPYLGNLPEPLHMPRRAEPRLQVPA
                     GSVGIGGAQTGIYPLSTPGGWQLIGLTPLKLFDPMRETPVLLRPGDSVRFVPQKEGIC
                     "
     gene            complement(5200..5943)
                     /gene="ybgI"
                     /locus_tag="OPY25_003109"
     CDS             complement(5200..5943)
                     /gene="ybgI"
                     /locus_tag="OPY25_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HCS0928663.1"
                     /translation="MKNTELEQLINDKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLQADAVIVHHGYFWKGESPVIRGMKRRRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVKGEIEPLVPWGELSMPVPGLELASWIEARLGRKPLWCGDT
                     GPENVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTALDVTFIDIPNPA"
     gene            6272..7753
                     /locus_tag="OPY25_003110"
     CDS             6272..7753
                     /locus_tag="OPY25_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928664.1"
                     /translation="MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDD
                     NHAYELFSAYCSLVYVTPILGGYLADKVLGNRMAVMLGAFLMAIGHLVLGASEIAPTF
                     LYLSLAIIVCGYGLFKSNISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGY
                     VQEEYSWAMGFALAAIGMLAGLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLI
                     LLVAAPLLITVLFWKEWSVYALIVATAIGLVVLAKIYRQAQTAKQRKELGLIVTLTLF
                     SMLFWAFAQQGGSSISLYIDRFVNRDILGYSVPTAMFQSVNAFAVMLCGVVLAWLVKE
                     SVSGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAAYGHSSMPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIDIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQSAFDASGAVNY
                     AINAYVDVFEQITWGALACVGVVLLIWLYQSFKFKSRALAVES"
     gene            complement(7792..9213)
                     /gene="phrB"
                     /locus_tag="OPY25_003111"
     CDS             complement(7792..9213)
                     /gene="phrB"
                     /locus_tag="OPY25_003111"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HCS0928665.1"
                     /translation="MPTHLVWFRRDLRLQDNLALAAACRDASARVLALYISTPAQWQA
                     HDMAPRQAAFISAQLNALQTALAEKGIPLLFHEVADFNASIETVKNVCRQHDVSHLFY
                     NYQYEFNERQRDAAVEKTLPSVICEGFDDSVILAPGAVMTGNHEMYKVFTPFKNAWLK
                     RLKEDIPPCVPAPKIRVSGALSIPLTPVSLNYPQQAFDAALFPVEENAVIAQLRHFCS
                     QGADEYASRRDFPAVDGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGPGSVWLNE
                     LIWREFYRHLMTWYPALCKHQPFIRWTKRVAWQENPHYFQAWQKGETGYPIVDAAMRQ
                     LNATGWMHNRLRMITASFLVKDLLIDWRLGERYFMSQLIDGDLAANNGGWQWAASTGT
                     DAAPYFRIFNPTTQRERFDRDGEFIRQWLPALRDIPGKAIHEPWRWAEKAGVVLDYPR
                     PIVEHKQARIATLSAYEAARKGA"
     gene            complement(9324..9530)
                     /locus_tag="OPY25_003112"
     CDS             complement(9324..9530)
                     /locus_tag="OPY25_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HCS0928666.1"
                     /translation="MEHYKDYPAHVIFARRAFAVTAGVLALPVMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMAQAEKATCDFY"
     gene            9867..9956
                     /gene="kdpF"
                     /locus_tag="OPY25_003113"
     CDS             9867..9956
                     /gene="kdpF"
                     /locus_tag="OPY25_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HCS0928667.1"
                     /translation="MSAGVITGIVLVFLLLGYLVYALINAEAF"
     gene            9956..11635
                     /gene="kdpA"
                     /locus_tag="OPY25_003114"
     CDS             9956..11635
                     /gene="kdpA"
                     /locus_tag="OPY25_003114"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HCS0928668.1"
                     /translation="MAAQGFLLIASFLLILLVLAKPLGSGLARLIAAVPLPGVAGVER
                     ILWRTLGITDHEMNWRQYLLALLTLNLLGLGILFCLLFWQEWLPLNPQRLPGLSWDLA
                     LNTAVSFVTNTNWQAYSGESTLSYFSQMAGLTVQNFLSAATGIAVVFALIRAFTRQNV
                     HTLGNAWQDLVRITLWILFPVALIIALFFIQQGVPQNLSAYQPITTLEGAKQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNLAQMLAIFLIPAALCFAFGEAAGD
                     RRQGRALLWAMSFIFVVCVAVVMWAEVQGNPHLLAAGADSSVNMEGKEARFGVLASSL
                     FAVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKMTALAILVTPMLVLLGSALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLV
                     SKKVQPASQGTLATHGALFIGLLIGTVLLVGALTFIPALALGPVAEHFSLP"
     gene            11656..13365
                     /gene="kdpB"
                     /locus_tag="OPY25_003115"
     CDS             11656..13365
                     /gene="kdpB"
                     /locus_tag="OPY25_003115"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HCS0928669.1"
                     /translation="MSRKQLALFEPVLLVQALTDAVKKLSPRAQWRNPVMFVVWAGSV
                     LATLLTLAMVTGQIAGSALFTGVISLWLWFTVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARRLRAPRHDAQADNVPAAELRKGDIVLVKAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGRAVEAAGDVDVLLLDKTGTITLGNRQASDFIPARGVDER
                     TLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINID
                     NRMIRKGSVDAIRRHVESNGGHFPADVEQNVENVARLGATPLVVVEGARVLGVIALKD
                     IVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQ
                     YQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVH
                     IGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNVMGLHSPNSAILSAV
                     IFNALIIIFLIPLALKGVSYKPLSASAMLRRNLWIYGLGGLVVPFIGIKVIDVLLTLL
                     DLA"
     gene            13374..13958
                     /gene="kdpC"
                     /locus_tag="OPY25_003116"
     CDS             13374..13958
                     /gene="kdpC"
                     /locus_tag="OPY25_003116"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpC"
                     /protein_id="HCS0928670.1"
                     /translation="MIGLRPAFSTMLFLLLLTGGVYPLLTTALGQWWFPWQANGSLIH
                     KDNLIRGSALIGQSFTAAGYFHGRPSATADTPYNPLASGGSNLAASNPELDAQIQARV
                     AALRAANPQASSAVPVELTTASASGLDNNLTPGAAAWQIPRVAAARQLPVEQVAQLVA
                     EYTHRPLASFLGQPVVNIVELNLALDALQGHRAK"
     gene            13955..16639
                     /gene="kdpD"
                     /locus_tag="OPY25_003117"
     CDS             13955..16639
                     /gene="kdpD"
                     /locus_tag="OPY25_003117"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HCS0928671.1"
                     /translation="MNDEPLRPDPDRLLEQTPPPHRGKLKIFFGACAGVGKTWAMLAQ
                     AQRLRAQGLDVVIGVVETHGRKETAALLDGLTILPPKRHSHRGRQIREFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADEVVLVDLPPDDLRQRLNEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDDQMRAWRAHPGEEKVWHTRDAILLCIGHNTGSEKLVRTAARLASR
                     LGSVWHAVYVETPTLHRLPEKQRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIVMGRPASRRWWRRDAFADRLARRAPDLDQVIVALEEPPARALAQTPDNRPFK
                     EKWRGQIQGCLVAVALCAITTFIAMQWLVTFDAANLVMLYLLGVVVIALLYGRWPSVV
                     ATVINVASFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSEHDIAATSERFIASTFQARSQILLPDTNGKLLPLTHQQG
                     MTPWDDAIARWSFDKGQPAGAGTDTLPGVPYQILPLKSADKTYGLAIVEPGNLRQLMV
                     PEQQRLLETFTLLVANALERLTLTASEEQARLASERESIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASAGSPHARQASEIRQHILNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLLHPITLSLPQQLTLIHVDGPLFERVLINLLENAVKYAGPQAS
                     IGIDAAVKDNRLQLDVWDNGPGIPAGQEQKIFDKFARGNKESAVPGVGLGLAICHAIV
                     EVHGGTLTAYNRPQGGACFRVTLPQGKPPELDDFHEDM"
     gene            16636..>17287
                     /gene="kdpE"
                     /locus_tag="OPY25_003118"
     CDS             16636..>17287
                     /gene="kdpE"
                     /locus_tag="OPY25_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HCS0928672.1"
                     /translation="MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFIIET"
BASE COUNT         3745 a         4870 c         4673 g         3999 t
ORIGIN      
        1 ccttattgat ataaggcatc atctcagcgt atttatttac ataattccat acagtttcat
       61 tatcagtatg aaaaatatga ggaccataaa cgtacaccat aatacccgtg tgctcatctc
      121 gggcatcata agcgttacta ccgatatgcg aacgttgatc aataatattg actacatgtc
      181 cctgctcggc taactggcgt gctattactg cgcctgaaag gcccgcacct acaattagta
      241 tctttttacg ttgcattatt tttgtcactc tgttcgcaga cacagataat attagatagt
      301 ttatccagaa ccattttcat ttatatcaga agagtaaagt gaaatttact caacgcatcc
      361 agataattcc acgctaccgc cacagcgcgt aaaccctcgc actgattaca gattcattaa
      421 tgttacacgt tatgcggtat ttccggacaa cgatgattgc catatttatt ttgtgaagat
      481 aactcattca gaacgcaaca ttatgggtct gaataccgcg cggcatgatg taaatatgct
      541 gtcagcataa atccggtgcg ttaccggccc cagtttttac caacccactc tgttgactga
      601 tgtccggacc gacgtccggt atccttattc ttaccgcatc agatagcggt actcctgtcg
      661 ggatatccca gcgttgtttc agcgtctgct ccgcgagcca gacctgcctc acgccggttc
      721 ccagcatacg ggccgtcatt tccgggctac agcctgacaa cagtaatccc agcacccgcc
      781 gtccctgttt tggcagacgc tctgacagta acctgaccag cgtgcggctg tttatctcca
      841 tcaccagctc cggcacgctc aacgcgcttt tcatctcctc ctcgtaaggc gatgtctgta
      901 gtgatgacca tatggcaagc tcagccattc tggccagaac ccttaccgac atggcgcgtt
      961 taatcagcct cagatggcgg aagtaacctt ccacgctgac gtcaaccggt aaaaacgcgt
     1021 tactgctgca aaaaaccact gtccgcggat aacgcagaaa aacctgttgc cacagcagaa
     1081 gctgggttga tggccgtccg gcggatatca ccatcgcgcc gggccaccga cgcaaccgat
     1141 ccagcagccc ttctggtgtc ctgagacgaa cgcagtcctc cacgcaaagg ccgccggtat
     1201 ccggaaactg cgtaggattt tcgcctgact gacaaaacat aatcagccgg agaggcggca
     1261 gtactctggt taacgtctgc atatcagtac gtcagaacct ggtacaggct gaacaacgct
     1321 gcgacggtgg agaccgccag caggagcaaa aatatttttg cgcccatact gtaccggcac
     1381 ttactggtcc ccccccttcc ggtggacatt tccgcatatt cttgcgtcat cagattgttc
     1441 tcctctggcc attgccgacc cggcactgcg ccagcaacgg cagcttcgtg ttgtggaaac
     1501 aacatgtccg caccctttcg tggaccggga gccattccat gtctgtatga aaaatgacgt
     1561 ctggccccat ctaaacactg ctctctgaca ccctgtccgg ttctgctttt cggctgcaca
     1621 ggccgtcagt ccccctggta gtacatgctc ctgccgtagg gtaattctgc cctgtgcgga
     1681 gtacaaaatg acaaatagaa aatacagtaa tctattgatt tatatgttga ttatgtaaat
     1741 cagctttccc tgaacagact tctctgtgat ttaacaatat gaatcagaac gtacggttat
     1801 actcgacgtt tttttcgcca tattccatga aaacgcccgg cgttacttgc ggtgtatctt
     1861 acggtgtgct ggatattcct gtgccccaga tagtcctgta tgagtcgtgt atcaatccct
     1921 ttatcagcaa gggcgtagcc gcaggcatgt cgcagcatat gaggatgtgg cgctatcgtt
     1981 aattcggcca accgccctgc ctcacgaagt atgtaaaaaa attgttgcct gctgagcgga
     2041 tgccgtcgta gcgacaggaa cagccagtct ccgtcagccc ctttctcaag atacttcctg
     2101 gccctgagcc agcttttcag tacgttatac tcatcgggaa ggagggggtg acacgttgaa
     2161 aagccatttt tgaggcgccg gatataaagc tgtcttcctg caagatcaat atccgacaag
     2221 cgcagcccca gcagctcact ggcccggaag ccgtgaataa acgccatcag gattaagcag
     2281 cggtttcttt ccgggaaggg cattctgtcg gtcgctgaca gcagtttttc aatctcttct
     2341 tgcgtaagat attttctttt cacaaaacaa atccatcata acaaaatgag taatatacta
     2401 aaaaatcact gatcagatga gtttaatttt cgctaaaaaa gttgctatgc gtaaacagct
     2461 taaaatccat atagctggca atctggcacg ctatccatga cgtgatagtg aaacagcgaa
     2521 tcaatctggc ttcaatctcc tgataagttg tcatgacgag gaatataaat gctaaaaatg
     2581 aggctatcgt gaggtaaatc aatcagaaag gggtaataga gagtcaggta gtttacccgc
     2641 cccggaggtt tgattagatg gcgatagcta acaatatcat agtgattttc aaaaactctg
     2701 ctgctaacag caataagctc atcatactgg ctattacagc atcacttggt tatttttaaa
     2761 ataatatatt ataaggggat ttatatagta ttgaataaat ccctcttcct gacattaaga
     2821 gaacagaaca cgataatttt tagcagccgt aatataatag cttcaatcgt cgggctctca
     2881 ggcaataacg tgtacattac gcgcattgaa cgcggcgcgt agcctgcgtg cgaatgcaag
     2941 cgcatactcg ccgtcgccat gaatgcacac cgtttgcgcc gtgacagtcg tccacacgcc
     3001 agtaacgctt ttcactctcc cggcttgtac catatccagc gtttgcgcca gcgcctgctc
     3061 ttcgtcgtga atcagcgcgc caggttgcat gcgcggcacc aggctaccgt cggcctgata
     3121 gccgcgatcg gcaaacacct cctgccgcgt caccaggcga tggcgttcac cggcccggat
     3181 cagctcactt cccgccagtc caaccagtat cagtgacgga tcatagtcgt gtaccgcttt
     3241 cgcaatcgcc tgtgccagat ggggatcttt cgccgcctgg ttatagagca taccgtgcgg
     3301 tttgacatgg cgcatcacgc cgccttgcgc ctggacaatc gcccccagcg cgccgatttg
     3361 gtacagcgtc tgggcgtata ccgtttccgg cggcaaaacc atcgccgtcc gcccaaaatt
     3421 atcccgatcc ggaaagctgg gatgcgcgcc gatcgccacg ccgtttttca gcgcctcgcg
     3481 cacgcaggtc agcatggttt gcgcatcacc ggcgtgaaaa ccacaggcga tattagcgga
     3541 ggagaccagc gttaataatt cgctgtcgct ggcgcaacct tcgcccaaat ccgcatttaa
     3601 atcaatgttc atgctgaagt cgccaggtaa gctgttccag atagcgccga cgctcgcggc
     3661 gcgcgttgag cgcctcctcc agcgaacatt gcacaaaatg gatcggttgt tctagcggga
     3721 tctgcgccag atggtacata tctgcctcga tgatgcaggc aatgcgcgga tagccgccag
     3781 ttgtctgggc atcattcatt aacacaatag gttggccgtt gtaaggcacc tgcacgacac
     3841 cgggcagcaa accgtgcgac agcagttcgc gatccgttgt ccgcgttaac gattgtccct
     3901 gcaaacgata gcccatgcga ttactttgcg gactgagctg ccacggcgaa cgccagaacg
     3961 cttcttgcga ggcgcgatcg aactcacggt attccggccc cggtagcgca cggatgcgat
     4021 tcccccacag taactgcttc acgccctgcg gcccgctaag ctgtcgcgat ggtttacccg
     4081 tcgccagccg atcgccatct tttagcagcc gtccttccag cccaccgatg ccggacttca
     4141 gatcggtact acacgatccc atcacctccg gcacagcaat accgcccgcc accgccagat
     4201 agctacgcat cccgtgaagc ggtcgatgca gcgtaagacg ctgacccgct tttaccggca
     4261 atcgccagcc ggtccagacc ggttgatcat ccaactgcgc ctcgcagcct gcgccggtaa
     4321 gagcgaacca ggtctcattt tcaaattcga caaccagttg accgagagtg atttccagcg
     4381 ccggggcatt cgcatcgttc ccgaccagga gattagcggt ctgaaaggcg ggtttatcca
     4441 gcgcaccgca gtgactcagc cccgactgac gaaagccgtg acgcccgcta tcctgcacgg
     4501 aggtgtaaat ccccgcgcga ataatattca gcatattccc tccttttgcg gcacaaagcg
     4561 tacgctatcg ccagggcgta gcagaaccgg ggtctcccgc atcggatcga ataacttcaa
     4621 cggcgtgagg ccgatcagct gccagccgcc cggcgtggat aatggataaa tccccgtctg
     4681 cgcgccgccg atgccgacag aaccggccgg aacctgcagg cgcggctctg cgcgtctggg
     4741 catatggagc ggttctggta aattcccaag atagggaaag ccgggctgaa agcctaaaaa
     4801 ccagacgaca tactcaacgg aggcatgtag ctccacgacc tgcttttcac tcaaaccgct
     4861 gtgccgtgcc accgccgcca gatccggccc gcctgcgccg ccatagatca ccgggatctc
     4921 aaccgaacgc gagtccggtt ccagcgcctc gctctcttcc caccagcgct gcagacgctc
     4981 aatcgcatcc agcgccagag tttgcggttc ccgcaagatc acggtgatat tgttcatccc
     5041 gggaatggct tccaccacgt tcggcatatc gaccagacgc tgcgtcagac gccagatgcg
     5101 tttctggctc gccagcgtaa tcggcggttc aagttccagg acgaccgccg tttcgcctaa
     5161 cagataacaa cgcgctcgct gcactttatt acctctcagt tatgccgggt tagggatatc
     5221 aataaacgtc acatccaacg ccgtgttttc gttcaaccat tcgctcaggg cgcgaatacc
     5281 gccgcgttca gtggcatggt gcccggcggc ataaaaatgc agcccctgtt cgcgtgcgga
     5341 atgaatggtc tgttcagaca cctcgccggt aataaaagca tccacgccga agcgggcggc
     5401 gctatcaata aaactttgtc cgccgccggt acaccaggcg acacgctgca cattctctgg
     5461 cccggtatcg ccgcaccata gcggtttacg ccccagacgc gcttcaatcc atgaggccag
     5521 ttccagcccc ggcaccggca ttgagagctc tccccacggc accagcggct caatttctcc
     5581 tttcacggta atgcccaata gcgccgccaa ctgcgcattg ttgcccagct cagggtgcgc
     5641 atccagcggc agatgccaac cgtaaaggtt aatatcattt gccagtaacg tttttaagcg
     5701 acggcgtttc atgccgcgaa taaccggaga ctcgcctttc cagaagtaac catgatgaac
     5761 aatgaccgca tcggcctgca aacgcaccgc ctcatcgagc agcgcctgac ttgcggtcac
     5821 gccggtaacg attttctgta ccgtctcttt tccttcgacc tgtaaaccat tcggcgcata
     5881 atcgcttatt gccgcactgt tcagcttgtc gttaatcagt tgttccagct cggtgttttt
     5941 catcatcgct ccctttaacc cacgttctac tttcccgtta cgggttcagt ctccgttaac
     6001 atagcctccc gttagccgtt cgtcgataaa catttgtttg acacatcaag aaacaatcac
     6061 ccccgggttt ggcgcaaatt acttagcaaa acacgatcgg tttcatgtat atttatgcaa
     6121 tcagaacgca tattgcagaa aaaatcagtt ctgtatcatg ttggtaactt taaggaaaca
     6181 cggcgatacg gcaggcttaa taagcccaca aagaaaggca ttatctgaga atgccgcgtt
     6241 cttgccgcag cgtctctatc ccggaaatac gatgaataaa caagcatctc aaccccgcgc
     6301 tatttactac gttgtcgccc tgcaaatttg ggagtacttc agcttttatg gtatgcgcgc
     6361 cctactgatt ctttatctca ccaatcagct aaaatacgac gataaccacg cctatgagtt
     6421 attcagcgct tattgttcgc tggtctacgt aacgccaatt ctcggcggct atctggcgga
     6481 taaggtgctt ggcaaccgaa tggcagtcat gctgggcgca tttttaatgg ctataggtca
     6541 tttagtgctg ggcgccagtg agatcgcgcc gacattcctt tatctgtcgc tggcgatcat
     6601 tgtctgcggc tacggcctgt ttaaatcgaa tattagctgc ctgctgggcg aactgtacca
     6661 gccggaagat ccgcgccgcg acggcgggtt ctcgctgctt tacgcagcgg gcaatattgg
     6721 ttcgatcgtg gcgcctatcg cctgcggcta tgtgcaagag gagtacagtt gggcgatggg
     6781 ctttgcgctc gccgccattg gtatgctggc ggggctggtg atcttcctgt gtggaaatcg
     6841 tcatttcacc cacactaccg gcgtgaataa agccgtgttg tgcgccagaa actacctgct
     6901 gccgaactgg ggctggctgt taattctgct ggtagcggcg ccgttgctga ttaccgttct
     6961 gttctggaaa gaatggtctg tctatgcctt aatcgtggcg accgcgatcg gcctggtcgt
     7021 gctggcaaaa atttatcgtc aggcgcaaac ggccaaacaa cgcaaagaac tggggctgat
     7081 tgtcaccctg accctgttca gtatgctgtt ctgggcgttt gcccagcagg gcggcagttc
     7141 tatcagcctg tatatcgacc gctttgtgaa ccgcgatatt ctgggctatt ccgttcctac
     7201 cgccatgttc cagtcggtga acgcctttgc cgtgatgctg tgtggggtcg tcctggcctg
     7261 gctggttaaa gagagcgtaa gcggtaatcg caccgtgcgt atctggggca aattcgcgct
     7321 gggtctcggt ctgatgagcg ccggattctg tattctgacc ctgagcgcac gctggtccgc
     7381 cgcttacgga cactcttcaa tgccgctaat ggtgctggga ctggcggtga tgggctttgc
     7441 cgagctgttt atcgacccgg tcgccatgtc gcaaattacg cgcattgata tccccggcgt
     7501 caccggcgta ttaaccggaa tttatatgct gctgtccggc gcgatagcta actatctggc
     7561 aggcgtcatc gctgaccaga cctcgcaaag cgccttcgac gccagcggcg cggttaatta
     7621 cgccatcaac gcctatgtgg atgtttttga acagatcacc tggggcgcgt tagcctgcgt
     7681 aggggttgtc ctgctgattt ggctgtatca gtccttcaaa ttcaaaagcc gcgcgctggc
     7741 cgtcgaatcc tgatagcaga aggcccggta gtttgcgcta ccgggcctgt atcacgcccc
     7801 ttttctcgcc gcctcatagg cggaaagcgt tgcgattctc gcctgtttgt gctccacaat
     7861 aggccgagga taatcaagta cgactcccgc tttttccgcc caccgccacg gctcgtgaat
     7921 cgcttttcca ggtatatcgc gtaatgccgg tagccactgg cggataaatt cgccgtcgcg
     7981 atcgaacctc tctctctgag tcgtgggatt aaaaatacga aaataaggcg cggcatcggt
     8041 accggttgaa gcggcccact gccagccgcc attattggcg gcaagatcgc cgtcaataag
     8101 ctgcgacatg aaatagcgct cccccaaccg ccagtcaatt agcagatctt ttaccagaaa
     8161 gctggcggta atcatgcgta aacggttatg catccagccc gtcgcgttaa gctggcgcat
     8221 cgccgcatcg acaatgggat aaccggtttc gcctttctgc catgcctgaa aatagtgcgg
     8281 gttctcctgc cacgcgacgc gttttgtcca gcggataaac ggctggtgtt tgcataatgc
     8341 cggataccag gtcattaaat gacggtaaaa ttcccgccag atgagctcat tcaaccagac
     8401 gcttcccggc ccgccgtcca gcgcctgcgg ctgctccgcc agtaatcggt gcaggcactg
     8461 tcgcggcgac aggccacccg tcgccaggct ggcggaaagc cgactggtgc cgtcaaccgc
     8521 agggaaatcg cgccgtgacg catactcgtc tgcgccctgc gagcaaaaat gacgtagctg
     8581 cgcgatgacc gcgttttctt ccaccgggaa aagcgcggcg tcaaacgcct gttgcgggta
     8641 gttaagcgag actggcgtta agggtataga aagcgcgccg ctcacccgga tcttcggggc
     8701 cggaacgcac ggcgggatat cctcttttag ccgtttcaac caggcgtttt taaacggcgt
     8761 aaaaacttta tacatttcat gattgccggt catcaccgcg ccgggcgcca gaatcacgct
     8821 atcgtcaaag ccttcgcaga tgacagatgg cagcgttttt tccaccgccg catcacgctg
     8881 acgctcgtta aactcatact gatagttata aaacagatgg ctgacgtcat gctgccggca
     8941 aacgttttta accgtctcaa tactggcgtt aaaatccgcc acttcatgaa acagcagcgg
     9001 aatccctttc tctgcaaggg ccgtctgtag cgcattgagc tgcgcgctga tgaatgccgc
     9061 ctgccgcggc gccatatcat gggcctgcca ctgggcgggg gtggaaatat aaagcgccag
     9121 cacccgcgcg gatgcatcgc ggcaggcggc ggccagcgca aggttatcct gtaaacgcag
     9181 atcgcgcctg aaccagacta aatgggtggg catacaactc ctgaaagatg aaacgtcacg
     9241 gcgaatagcg ttaaacagtg tagaccctgg cgcataaaaa aaccgccagc gtggcggctg
     9301 acggtttttc aggctggtcg cgattaataa aagtcgcagg tggctttttc agcctgcgcc
     9361 atccataccg gtttatcact ggttttcgac cagacacggt gcagataact ataaaaacgc
     9421 gcgcggtctt tccagaagag catcaccggc aacgccagca cgcctgcggt caccgcgaaa
     9481 gcacgacgtg caaaaatgac atgcgctgga tagtctttat agtgttccat acgtttcccc
     9541 cctttatacc gacgctatcc gccccggtat agattgaatc ggtgaatagc accgaaaaat
     9601 tgaacctcgt tacctgatta aaatagtacc gctttcggtg taatttcact actcatccga
     9661 ccacttattt tcacgctttt ccagcagatt tacattcaaa gcgtaaatta gttacaaaaa
     9721 ggttaaatta atactaatca ttagttaaat aatggtcttt gccattttta tacttttttt
     9781 acactccgcc cgccaatttt tgcgaaatct ttgcagccaa aaaattacct ttctcaggag
     9841 taaaacaatg ccactggagg tgctctgtga gtgcaggcgt gataaccggc atcgtgctgg
     9901 ttttcttact tttaggttat ctggtctatg ccctgattaa tgcggaggcg ttctgatggc
     9961 cgcgcaagga tttttactga tcgccagttt tttactgatt ttattggtac tggcgaaacc
    10021 gttgggttcg ggcctggcaa ggctcatcgc cgccgttccg ttgccgggcg tggctggcgt
    10081 tgagcgtatc ctctggcgga ctcttggcat taccgaccac gaaatgaact ggcgtcagta
    10141 tttactggcg ctactgacgc tcaatctgct gggactgggc atcctgtttt gcctgctatt
    10201 ctggcaggag tggctgccct taaatccgca gcggctaccg gggctgtcct gggatctggc
    10261 gctgaatacc gccgtcagct ttgtcaccaa taccaactgg caagcctaca gcggcgaaag
    10321 cacgctgagc tactttagcc agatggcggg gctgacggtg caaaatttcc tgtcggcggc
    10381 gaccgggatt gcggtggttt ttgcacttat ccgcgccttt acgcgccaga atgtgcacac
    10441 gctgggtaat gcctggcagg atctggtacg cattacgcta tggatattat ttcctgtcgc
    10501 gttaattatc gcgctgtttt ttatccaaca gggcgtaccg caaaacctgt cggcttatca
    10561 gcccatcacc actcttgaag gcgctaaaca actcttgccg atggggccgg ttgcttcgca
    10621 ggaggcgatc aaaatgcttg gcaccaacgg cggaggtttc tttaacgcca actcttcgca
    10681 tccgttcgaa aatcccaccg cgctcactaa tctggcgcag atgctggcga tatttttgat
    10741 tccagccgcg ctctgtttcg cctttggcga agcggcgggc gatcgccgtc agggacgcgc
    10801 cctactgtgg gcaatgtcat tcatttttgt ggtctgcgta gcggtagtga tgtgggcgga
    10861 agttcaggga aatccacatc tgttggcggc aggcgcggac agtagcgtca acatggaagg
    10921 taaagaggca cgctttggcg tgctggccag cagcctgttt gccgtcgtca cgaccgcggc
    10981 gtcctgcggg gcggtaaatg ccatgcacga ctcgtttacc gctctgggcg gtatggtgcc
    11041 gatgtggctg atgcaaattg gcgaagtggt ctttggcggc gtcggttcag ggctgtacgg
    11101 catgttgctg tttgtcctgt tggcggtgtt tatcgcgggg ctgatgatcg gtcgcacgcc
    11161 ggagtatctg gggaaaaaaa tcgacgtgcg cgaaatgaaa atgaccgcgc tggcgattct
    11221 ggtcacgccg atgctggtct tgttgggttc ggcgctggcg atgatgacgg atgccggacg
    11281 cagcgcaatg ctgaaccctg gcccgcacgg ttttagcgaa gtgctatatg ccgtctcctc
    11341 tgccgccaac aacaacggta gcgcctttgc aggtctgagc gctaactcgc ctttctggaa
    11401 ctgtttgctg gcgttctgca tgttcgtcgg acgtttcggc gtgattattc ctgtcatggc
    11461 catcgccgga tcgctggtca gtaaaaaagt acagccggcc agtcagggaa cgctggcgac
    11521 ccacggcgcg ctatttattg gactgctcat tggcacggta ctgctggtcg gcgcgctgac
    11581 gtttattcct gccctggcgc ttggcccggt agcggaacat ttctctttac cttgagcgat
    11641 gcggagtaca ttgatatgag tcgcaagcaa ctggcgctgt ttgaacctgt tttactcgta
    11701 caggcgctaa cggatgccgt aaaaaaatta agcccacgcg cccagtggcg taacccggtg
    11761 atgtttgtgg tctgggccgg cagcgtgcta gccactctgt taacgctcgc tatggtaaca
    11821 ggacaaatag cgggaagcgc cttgtttaca ggggtgatca gcctgtggtt atggttcacc
    11881 gtactgttcg ccaattttgc cgaagcactg gcggaaggcc gcagcaaagc ccaggcaaac
    11941 agtctgaaag gggtgaaaaa gaccgcgttc gctcgccgtc tgcgcgcccc gcgccatgat
    12001 gcgcaggccg ataacgtgcc cgccgctgaa ctgcggaaag gcgacattgt cctggtcaaa
    12061 gcgggcgata ttattccctg cgacggcgag gtcatcgaag gcggcgcctc ggtggatgaa
    12121 agtgcgatta ccggcgaatc cgcgcccgtg atccgcgagt ccggcggcga tttcgcctct
    12181 gtcaccggcg gccgcgccgt agaagccgcg ggcgatgtcg acgtgttact gctggataaa
    12241 accggcacta tcacgctcgg caaccgccag gcgtccgatt ttatacccgc ccgaggggtg
    12301 gacgaacgca cgctggctga cgccgcgcag ctcgcttcgc tggccgacga aacgccggaa
    12361 ggccgcagca ttgtgatcct cgccaaacag cgctttaacc tgcgtgaacg cgatgtgcag
    12421 tcgcttcatg ccacctttgt tccgtttacc gcgcaaagcc gcatgagcgg gattaatatc
    12481 gataaccgga tgatccgtaa aggctcggtg gacgcgattc ggcgtcatgt cgagagcaat
    12541 ggcggccatt ttcccgccga tgtcgagcaa aacgtcgaga acgtggcgcg tctgggcgcg
    12601 acgccgctgg tggtcgtgga aggcgcgcgc gtactgggtg ttatcgccct caaggatatc
    12661 gttaaaggcg gcattaaaga acgtttcgcc cagctacgaa agatgggcat taaaacggtg
    12721 atgatcactg gcgataaccg cctgacggcg gcagcgattg ccgccgaagc cggtgtggac
    12781 gattttcttg ccgaagccac gccggaagcc aagctggcgt tgatccgtca atatcaggcg
    12841 gaaggacggc tggtcgccat gaccggcgac ggcactaacg atgccccggc gctggcgcag
    12901 gctgacgtcg cggtggcgat gaactccggc acccaggcgg cgaaagaagc cggtaatatg
    12961 gtggatctgg actctaaccc gaccaagttg attgaagtgg tgcatatcgg taagcagatg
    13021 ctgatgacgc gcggctcgct caccaccttc agtatcgcga atgatgtagc gaaatatttc
    13081 gccattattc ccgccgcgtt tgccgctacc tatccgcagc taaacgcgct caacgtgatg
    13141 gggctgcatt cgccgaactc cgccattctg agcgcggtga tctttaacgc cctgattatc
    13201 atatttctga tcccgctggc attaaaaggc gtgagttata agccgctttc cgcatcggcc
    13261 atgctgcgcc gtaatttatg gatctatggt ctgggtggtc tggtggtgcc gtttattggc
    13321 atcaaagtga ttgatgtgct gctgaccctg ctggatctgg cgtgaggtgt atgatgatcg
    13381 gtttacgtcc tgctttttcg acaatgttat ttctgctgtt attgaccggc ggcgtgtatc
    13441 cgcttctgac cacggcgctg gggcagtggt ggtttccctg gcaggctaat ggctcgctga
    13501 ttcataaaga caatctgata cgcggctcag cgcttatcgg acaatcgttt accgccgcgg
    13561 gctattttca tggccggccc tccgccaccg ccgatacgcc ttataatcca ctggcgtcgg
    13621 gcggaagcaa cctggccgcc agcaatcccg aactggatgc gcaaattcag gcccgcgtcg
    13681 ccgcgctacg cgccgctaac ccccaggcga gttccgcggt tccggttgag ctgacgacgg
    13741 cgtcggcaag cgggctggat aataatctga cgcccggcgc cgcggcatgg caaatccccc
    13801 gcgtggcggc ggctcgccag cttcccgttg aacaggtcgc gcaactggtt gcagaatata
    13861 cgcacaggcc gctggcgagc tttcttgggc aaccagtggt gaatattgtt gagcttaatc
    13921 tggcgctgga tgcgctacag ggacacagag cgaaatgaac gacgaaccct tgcgtcctga
    13981 tccggatcgc ttgttggaac aaacgccccc gccccaccgg gggaagttaa aaattttctt
    14041 cggcgcctgc gcaggcgtcg gaaaaacctg ggcgatgctg gcgcaagcgc agcggctgcg
    14101 agcgcagggg ctggatgtgg tgatcggcgt ggtagagacg cacggccgta aagagaccgc
    14161 cgcgctactt gacgggctga ccattctgcc gccaaaacgt cactcgcacc gggggcggca
    14221 aattcgcgaa tttgacctgg atgccgccct cgcccggcgt ccggcgctga ttttaatgga
    14281 tgagctggcg cacagtaacg cgcctggctc acgccatcct aagcgctggc aggatattga
    14341 agagctgctg gaagcgggaa tcgacgtttt caccaccgtg aacgtacaac atctggaaag
    14401 tctgaatgat gtggtgagcg gcgtcacggg gattcaggtg cgcgagaccg tccccgatcc
    14461 cttttttgat gccgctgatg aagtcgtact ggtcgatctg ccgcccgacg atctgcgcca
    14521 acggctcaac gaaggtaaag tgtatatcgc cggtcaggcg gaacgcgcta ttgaacattt
    14581 tttccgcaag ggcaatctga tcgccctccg cgagctggcg ctacgccgga cagccgatcg
    14641 cgtggacgat cagatgcgcg cctggcgcgc gcatccgggc gaagaaaaag tatggcatac
    14701 ccgcgatgcg attttactgt gtatcgggca taacactggc agcgaaaaac tggtgcgtac
    14761 cgcggcgcgt ctggcctccc ggctcggcag cgtctggcac gccgtctatg tcgaaacgcc
    14821 aacgttacac cgcttaccgg aaaaacaacg gcgggctatt ttaagcgcgc tgcgcctggc
    14881 gcaggagctt ggcgcggaaa ccgccaccct gtccgatccc gccgaagaga aagcggtcgt
    14941 gcgctatgcc cgcgagcata atctggggaa aatcgtcatg ggccgcccgg cgtcgcgacg
    15001 ctggtggcga cgtgacgctt tcgccgaccg tcttgccagg cgcgcgccgg atctcgatca
    15061 ggtaatcgtc gcgctggaag agccgccagc gcgcgcgttg gcgcaaacgc ctgataaccg
    15121 accttttaaa gagaaatggc gtggacagat tcagggctgt ctggtcgccg tggcgctttg
    15181 cgccataacc acgtttatcg ctatgcagtg gcttgtcacc ttcgacgccg ccaatctggt
    15241 gatgctctat ttgctgggcg tagtggtgat tgcgctgctt tacggacgct ggccgtcggt
    15301 ggtggcgacg gtgattaacg tggcgagttt cgatctcttt tttatcgcac cacgcggtac
    15361 gctcgccgtt tcggacgtgc agtatttgct gacctttgcc gtgatgctga cggttggtct
    15421 ggtgattggc aatcttactg ccggggtgcg ctatcaggcg cgcgtcgccc gttatcggga
    15481 acagcgtacc cgccatttat atgaaatgtc taaagcgctg gccgtcgggc gtagcgaaca
    15541 tgatatcgcc gcgaccagcg agcggtttat cgcctcgacg tttcaggcgc gcagccaaat
    15601 tttattacct gatactaacg gtaagttgct gcctctcacc caccagcaag gcatgacgcc
    15661 gtgggacgac gcaattgcgc gctggagttt tgataaaggc cagcctgccg gcgcaggcac
    15721 cgataccctt cctggcgtgc cttatcaaat cctgccgctg aaaagcgccg ataaaacgta
    15781 cggtctggct atcgtcgaac cgggtaattt gcgtcagtta atggtgccgg agcagcaacg
    15841 cctgctggaa acattcactc tgcttgtcgc caacgcgctg gaacgactga cgctgaccgc
    15901 cagcgaagaa caggcgcgtc tcgccagcga gcgcgaaagt attcgcaacg ctctgctggc
    15961 ggctctgtcg catgatttac gcacgccgct gacggtattg ttcggccagg cggaaatttt
    16021 gacgctggat ttagccagcg caggatcgcc ccacgcgcgt caggccagtg aaatccgcca
    16081 gcatattctc aacaccaccc ggctggtgaa taatttgctg gatatggcgc gtattcagtc
    16141 cggcgggttt aatcttaaaa aagagtggct gacgctggaa gaggtcgtcg gtagcgcgtt
    16201 acagatgtta gagccgggtt tattgcatcc gattacattg tcgctgccgc aacagttaac
    16261 gcttatccat gtcgatggcc ccttatttga gcgtgtcctg atcaacttgc tggaaaacgc
    16321 cgttaagtac gccgggccgc aggccagtat cggcattgat gctgcggtta aggacaatcg
    16381 tttacaactg gatgtctggg ataatgggcc gggtattcct gcggggcaag aacagaagat
    16441 tttcgataag ttcgcccgcg gcaacaaaga gtccgccgtc cccggcgtgg ggctggggct
    16501 ggcgatttgc catgctatcg tagaggtaca cggcggcacg cttaccgcct ataatcgacc
    16561 gcagggcggc gcctgtttcc gtgtgacgct gccgcaagga aagccacctg aacttgacga
    16621 ttttcatgag gatatgtgac aaacgttctg attgttgaag atgaacaggc catccgccgc
    16681 tttctgcgcg ccgcgctgga aggcgacggc ctgcgcgtgt atgaagctga aacattacaa
    16741 cgtggtttac tggaagccgc cacgcgaaag cccgatctga ttattctcga tctcggcctg
    16801 ccggacggcg acggaatcga ttttattcgc gacctgcgtc agtggagcgc aataccggtg
    16861 attgtccttt ccgcccgcag cgaagaaagc gataagattg ccgcgcttga cgccggagct
    16921 gatgattacc tgagcaagcc attcggcatt ggcgagttgc aggcgcgttt gcgtgtcgcg
    16981 ctgcgacggc acgccgccag cccttgcgcc gatccgatcg tccgcttttc cggcgtgacg
    17041 gtcgatctcg ccgcacggtt gatccaccgt ggcgacgaag aaatccatct gacgccgatt
    17101 gagttccgcc tgctggcggt attactcaat aatgccggca aggtattaac ccaacggcag
    17161 ttattaaacc aggtctgggg ccctaacgcc gtggagcata gccactattt gcgcatctat
    17221 atgggacatt tacgccagaa actggaacaa gatcccaccc gcccacgcca ttttattatc
    17281 gaaaccg
//
LOCUS       DAJVKX010000092        17026 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000092 DAJVKX010000000
VERSION     DAJVKX010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17026
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.092"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(551..1456)
                     /locus_tag="OPY25_003119"
     CDS             complement(551..1456)
                     /locus_tag="OPY25_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HoxN/HupN/NixA family nickel/cobalt transporter"
                     /protein_id="HCS0928673.1"
                     /translation="MLSAAILAYSFGLRHAVDADHIAAIDTVTRKLMQQGKTPLGVGA
                     FFSLGHSTIVVLACLAIVVTSMAFRDRIDVLHQYGSLIGTAVSAFFLLAMALLNLFIL
                     FNVWRQFRSVTRGESVGAHDEAIPGGLMTRIFQRTFRLVTSSWHMYFVGFLFGLGFDT
                     ATEVGLLGISASAANQGLSLWSMMIFPVLFTAGMALVDSLDNFVMVGAYGWAFSHPLR
                     KLYYNITITAASVIVALAIGGLEALGLIDDALQLSGTFWQTVSTLNDHMGNVGFWVVG
                     AFVLFWLLSLLNYRWRGYDKITLNT"
     gene            complement(1697..3112)
                     /locus_tag="OPY25_003120"
     CDS             complement(1697..3112)
                     /locus_tag="OPY25_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCS0928674.1"
                     /translation="MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAY
                     DRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFELNMNDRLYYKVVDPSGKVISGYD
                     DLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEVYVAETLQ
                     SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLP
                     ELLPWSETRLLIVAFNRYIDRLRGILSRQERFSADASHQLKTPLAVLKTQAAVALASQ
                     HPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSPVNLYDIVQSGCFTR
                     LAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDG
                     DAVTLVVEDSGPGIDNEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHF
                     SRSEALGGLYVRIRFLSLVPQ"
     gene            complement(3099..3773)
                     /gene="tctD"
                     /locus_tag="OPY25_003121"
     CDS             complement(3099..3773)
                     /gene="tctD"
                     /locus_tag="OPY25_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TctD"
                     /protein_id="HCS0928675.1"
                     /translation="MRLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEM
                     YALMVLDINMPGMDGLEVVQRLRKRGQTLPVLLLTARSAVADRVKGLNVGADDYLPKP
                     FELEELDARLRALLRRSAGLVHEVQQLGELIFHDEGYFLLQGQPLALTPREQALLTVL
                     MYRRTRPVSRQQLFEQVFSLNDEVSPESIELYIHRLRKKLQGSDVRITTLRGLGYVLE
                     RGDEVG"
     gene            3928..4737
                     /locus_tag="OPY25_003122"
     CDS             3928..4737
                     /locus_tag="OPY25_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HCS0928676.1"
                     /translation="MKKQLLRTLTASILLMSTSVLAQEAPSRTECIAPAKPGGGSLLN
                     LSQGKFGRYGVDDVRWLASVGTDYGMIAVRADSPWKTLKDLMTAMEKDPNSVVIGAGA
                     SIGSQDWMKSALLAQKANVDPHKMRYVAFEGGGEPVTALMGNHVQVVSGDLSEMVPYL
                     GGDKIRVLAVFSENRLLGQLANVPTAKEQGYDLVWPIIRGFYVGPKVSDADYQWWVDT
                     FKKLQQTDEFKKQRDLRGLFEFDMTGQQLDDYVKKQVTDYREQAKAFGLAK"
     gene            4749..5183
                     /locus_tag="OPY25_003123"
     CDS             4749..5183
                     /locus_tag="OPY25_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461713.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HCS0928677.1"
                     /translation="MMSDRIFAGIWLLLCIAGLFIAWQIQSEYSYEPVGPRPFPLGII
                     GLMALCALALLLRHPDTVSWPRRHVLQKLITMIIILLMYAWGFEWLGFPIATALLTMV
                     IGMLFGATIPAAGISGAVLGILLWYAFDRLLDVTLPLGAWLS"
     gene            5194..6708
                     /locus_tag="OPY25_003124"
     CDS             5194..6708
                     /locus_tag="OPY25_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003846009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HCS0928678.1"
                     /translation="MDTWICLSQGFAVAMTPENLVIALIGCFVGTIVGLLPGLGPING
                     VAILLPLAFALHLPAESALILLATVYIGCEYGGRISSILLNVPGDAAAIMTALDGYPM
                     AQQGKGGVALSISAVSSFFGSLIAIGGIILFAPLLAQWSLAFGPAEYFALMVFAIACL
                     GSMMAQNPLKSFLAALIGLGLATVGVDANTGVYRFTFDSVHLSDGVQFIVVVIGLFSV
                     SEILLMLEHTSSGQTMVRKTGRMLFNLKEGAQCIGTTLRSSVIGFFVGVLPGAGATIA
                     SAITYMTEKKLSGNSDSFGKGDIRGVAAPEAANNASACGSFIPMLTLGVPGSGTTAVM
                     MGALTLYNITPGPAMFTEQPDIVWGLIAALLIANVMLLIMNIPLIGLFTRMLTIPLWF
                     LVPAIAAVSAVGVYAVHSPTFDLVLMVALGVLGYILRKMHFPMSPLILGCVLGEMLEQ
                     NLRRALSISNGNMAILWQSGVAKALLIMAIIVIVVPPVLRLIRKHSRKPQVDAS"
     gene            7011..7988
                     /gene="csiD"
                     /locus_tag="OPY25_003125"
     CDS             7011..7988
                     /gene="csiD"
                     /locus_tag="OPY25_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417145.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HCS0928679.1"
                     /translation="MNALTAVKANTDDLAQRHTGFILAPSAQSPRLLALTFTADTTRQ
                     FLHQVAQWPVQALEYKSFLRFKIGKILDDLCGNQLQPLLIKTLLNRAQGALLISAEGI
                     DDVAQAEEMVKLATAVAHLIGRSNYDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEVTDYVLMMKIDEQNMEGGNSLLLHLDDWEHLESFFTHPLARRVMRWAAPP
                     SKNVSHDVWHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDALETSQNILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYAASHYQTHQ"
     gene            8014..9282
                     /gene="lhgO"
                     /locus_tag="OPY25_003126"
     CDS             8014..9282
                     /gene="lhgO"
                     /locus_tag="OPY25_003126"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HCS0928680.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESAPACHQTG
                     HNSGVIHAGVYYTPGSLKARFCLAGNQATKTFCDQNNIRYDTCGKMLVATSELEMARM
                     RALWERTAANGLEREWLNAAELREREPNIIGLGGIFVPSSGIVSYRDVATAMANRFQA
                     KGGEIIYHAEVSALTEHAAGVIIRTSQGREIETATLIGCAGLMADRLVKMLGVEPGFI
                     ICPFRGEYFRLAPRHNRIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLALKR
                     EGYRKRDVSFTDTLEIFRSAGIRRVLQNHLLSGLGEMKNSLCKSGYLRRVQKYCPSLT
                     VNDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRSIHTCNAPSPAATSAIPIGAHIVSK
                     VQALRASQSNPGRTLRAARSVDALHAAFTR"
     gene            9304..10752
                     /gene="gabD"
                     /locus_tag="OPY25_003127"
     CDS             9304..10752
                     /gene="gabD"
                     /locus_tag="OPY25_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HCS0928681.1"
                     /translation="MQLNDSTLFRQQAFIDGDWRDARGGDVIPVSNPANGKPLGNVPK
                     MGAEETRDAINAANRALPAWRALTAKERANILRRWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQTDKRLLVIKQPIGVTAAITPWNFPS
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAQRAGILAGVFNVVTGSAGDIGG
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLNQAVNKLAVGDGLQADVAIGPLIDE
                     KAVAKVQEHIADALEKGARVITGGEAHKLGGNFFQPTILADVPDNAKVAKEETFGPLA
                     PLFRFSDEADVIRQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            10767..12050
                     /gene="gabT"
                     /locus_tag="OPY25_003128"
     CDS             10767..12050
                     /gene="gabT"
                     /locus_tag="OPY25_003128"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HCS0928682.1"
                     /translation="MNTNNTLMQRCHNAVPRGVGQIHPIFAERAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPGIVSAVEAQLKKLSHTCFQVLAYEPYLALCERMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGAIAFSGAYHGRTHYTLSLTGKVHPYSAGMG
                     LMPGHVYRALYPCPLHNISDDDAIASIERIFKNDAAPEDIAAIIIEPVQGEGGFYAAS
                     PAFMQRLRALCDQHGIMLIADEVQSGAGRTGTLFAMEQMGVAADITTFAKSIAGGFPL
                     AGVTGRADVMDAIAPGGLGGTYAGNPIACVAALAVLDIFEQENLLQKANTLGKTLRDG
                     LMEIAETHREIGDVRGLGAMIAIELFENGDPGKPNATLTADIVARAREKGLILLSCGP
                     YYNILRILVPLTIEASQIRQGLEIIAQCFDEAKQA"
     gene            12180..13580
                     /gene="gabP"
                     /locus_tag="OPY25_003129"
     CDS             12180..13580
                     /gene="gabP"
                     /locus_tag="OPY25_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HCS0928683.1"
                     /translation="MGQLSESHALGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGPWAGYTIGWLYWWFW
                     VLVIPLEANIAAIILNSWIPGIPVWLFSLVITLALTGSNLLSVKNYGEFEFWLALSKV
                     IAILAFIALGAAAISGFYPYAGVSGISRLWDHGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPDKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKSVGSYRSV
                     LELLHIPHAKFIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAIMGKTNRSKTP
                     WVAVLLSTGAAFLTVIVNYYAPAKVFKFLIDSSGAIALLVYLVIAISQLRMRKILLAQ
                     GGEIKLKMWLYPWLTWLVIGFICFVLVVMLFRPAQQLEVISTGLLGLGIIGTVPIMSR
                     WKKLIRWQKAPLQNLR"
     gene            13622..14299
                     /gene="csiR"
                     /locus_tag="OPY25_003130"
     CDS             13622..14299
                     /gene="csiR"
                     /locus_tag="OPY25_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HCS0928684.1"
                     /translation="MTALSQPTAIDGYRWLKNDIIRGTYQPDEKLRMSLLTARYALGV
                     GPLREALSQLVAERLVTVVNQKGYRVASMSEAELLDIFDARANMEAMLVRLAIERGDD
                     AWEAEILARAHMLSKLEASDASEHMLDEWDQRHQAFHSAIVAGCGSHYLLQMRERLFD
                     LAARYRFIWLRETVLSVEMLEDKHIQHHTLTEAILAREAARASELMRQHLLTPIPIIR
                     QAMAGKM"
     gene            complement(14321..14770)
                     /gene="lysM"
                     /locus_tag="OPY25_003131"
                     /pseudo
     CDS             complement(14321..14770)
                     /gene="lysM"
                     /locus_tag="OPY25_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461721.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein LysM"
     gene            complement(14870..15028)
                     /locus_tag="OPY25_003132"
     CDS             complement(14870..15028)
                     /locus_tag="OPY25_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HCS0928685.1"
                     /translation="MGFWRIVFTIILPPLGVLLGKGFGWAFILNILLTLLGYIPGLIH
                     AFWVQMRH"
     gene            15211..15510
                     /locus_tag="OPY25_003133"
     CDS             15211..15510
                     /locus_tag="OPY25_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCS0928686.1"
                     /translation="MTELEKLQASAEQAAALLKAMSHPKRLLILCMLCGSPKTSAGEL
                     ARITGLSPSATSQHLARMREEGLIDSQRDAQRIHYFIKNEAVNTLIATLKNLYCP"
     gene            15520..16047
                     /locus_tag="OPY25_003134"
     CDS             15520..16047
                     /locus_tag="OPY25_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese family protein"
                     /protein_id="HCS0928687.1"
                     /translation="MSIGIVSPREAQALIAQGAKLIDVRDADEYLREHIPHAQLAPLS
                     RLEQGDLPANLRAEQIIFHCQSGKRTSSNAAKLQAIAAPAQVSLLEGGIDGWKAAGLP
                     VTEDKSQPLPLMRQVQIAAGGLTLLGVILGYTVHGGFFLISGFVGAGLMLAGITGFCG
                     MARLLEKMPWNTRTH"
     gene            16126..16306
                     /locus_tag="OPY25_003135"
                     /pseudo
     CDS             16126..16306
                     /locus_tag="OPY25_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494935.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16396..16797)
                     /gene="stpA"
                     /locus_tag="OPY25_003136"
     CDS             complement(16396..16797)
                     /gene="stpA"
                     /locus_tag="OPY25_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HCS0928688.1"
                     /translation="MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     ELQQRQLAEKQEKINAFLELMKADGINPEELFAMDSAMPRSAKKRQPRPAKYRFTDFN
                     GEEKTWTGQGRTPKPIAQALAAGKSLDDFLI"
BASE COUNT         3988 a         4596 c         4493 g         3949 t
ORIGIN      
        1 attaacacgg tatgttacag ataacgtgct aaaaagcgtg cagcggttat acattttcat
       61 atgtgtgtgt cattaacctg gcgtcaggaa cagatgatga tgacaactac cattttatct
      121 cttctggcct ggcataccgt cagtagatta aaggtgtagc cttgctttat ggcattacaa
      181 aaatgtgggt gaggtctatg ctcaatgtat acgttatttg taacaacgct cttgtgcata
      241 aacaatacgt tattgccaac agcactgaac gggtacagtg gttcttgctg acaacaggct
      301 taaagatcgt cttaacacgg gatacctgat aactggatta tattatgaca catgcagact
      361 ggctgattct tgggtataca actgttatta ttatttttgg tattgtatgt tatatcggat
      421 tgcttaaatt gataacgaaa ggcaagcatg aaaaataacg cacttaccgg gaagaatata
      481 ctctcaggag ataaaatgct tcggcaatga tatgacacca ctgccgaaat gctattttta
      541 cagaaatcaa tcaggtattg agggtgattt tatcatagcc gcgccagcga taattcaaca
      601 acgagagcag ccagaatagc acaaaagcac ccactaccca gaagcccaca ttccccatat
      661 gatcgttaag cgtgctgacg gtctgccaaa atgttccgct taactgtaac gcatcatcaa
      721 tcaaccccag cgcttcaagc ccgccaatcg ccagcgcgac aatgacggat gcggcggtaa
      781 tggttatatt ataataaagc ttacgtaatg gatgcgagaa agcccaaccg taagcgccga
      841 ccatgacaaa gttatccagg gaatctacca gcgccatccc ggcggtaaac agcacaggaa
      901 aaatcatcat tgaccagaga gatagcccct ggttagctgc tgaagcggaa atgcccagca
      961 acccaacctc ggttgcggta tcaaatccca agccaaacag aaaaccgaca aaatacatat
     1021 gccaactgga agtgaccaaa cgaaacgtac gctgaaatat acgcgtcatc agcccgccag
     1081 gtatcgcctc gtcatgcgcc cccactgact cgccgcgggt aaccgagcga aattgccgcc
     1141 agacgttgaa caaaataaac aggttgagca gggccatcgc cagcagaaaa aaagcggaaa
     1201 cagccgtacc aatcaacgaa ccatattgat gcaaaacatc aatacgatcg cgaaatgcca
     1261 tcgacgtcac aacaatcgcc agacatgcca gaacgacaat ggtcgaatga cccaatgaaa
     1321 aaaacgcccc cacgcctaaa ggcgttttac cctgctgcat cagtttacgg gtgacggtat
     1381 cgatggctgc gatatgatcg gcatcaaccg catgacgcag cccaaagcta tacgccagta
     1441 tggctgcgct tagcatgact gcatggtgat gaaaaacaca gaacgcccaa atctaggcca
     1501 ggatgttaac cccgacaaga aagacggtta atgctattcc ccgtcgttta gtatgattat
     1561 tcatgcccct gcacccacta tagttttaat taacgctacg gtttgtaggg ggaatgtatg
     1621 atcatttgat taaaacgtca cacctcaaga tgcgactttt tgtaaacgtg ctttaccgct
     1681 gacacatttg tgcgcattac tgcgggacaa ggcttaaaaa gcgtatccga acgtataacc
     1741 ctcccaacgc ttcgctacgg gaaaaatggg gatgagtacg gtgcaagcgt gcgatatcat
     1801 tgaccaaagc cagaccaatg cccgccccgg ccacatttcc tacgttatcg agccggtgga
     1861 acggctgtag cgccagatgg atgtgttcat tatcaatgcc ggggccgcta tcttcgacaa
     1921 ccagcgtcac ggcatcgcca tcccgttcaa gccgcgcggt gacaatgcct tgctcaggcg
     1981 tgtatttcag cgcattatcc agcaagtttc cgcacagctc gctaagcagt acctcatccc
     2041 cctcgatcca catcgcttcc tgttcgcctt cgtagcccag gtcgatatgt ttactgcgcg
     2101 cctgcgccag gcgggtaaag cagccgctct gtacgatatc gtacagattc accggggaaa
     2161 aacgcctctc gccctgctct ttatgcttta ccgcagaaag ttgcaacaat ctttccgtga
     2221 gctgaatggt gctatccagc gttacgctca tcgcctgcag actttcgtac cagtgatgag
     2281 ggtgctggct ggctaacgcc accgccgcct gcgtttttaa caccgccagc ggcgttttta
     2341 actggtgaga agcatcggcg ctaaagcgtt cctgccggga aaggatgccg cggagcctgt
     2401 caatgtagcg attaaacgcc acgattaaca agcgtgtttc cgaccacggc agcagttccg
     2461 gcagcggcgt taacagaccc ggttcgcggc gtaccattaa tgacgaaagt tgacgcatag
     2521 ggcgcaggat ccggcgtaat aaccagccaa ccagcaccag ggtcagcaac accagcagcc
     2581 cctgtgagat ccaggaagag aacagcagtt ggcccgccag ataacgacgg gactgcagcg
     2641 tttctgcgac ataaacctcc gccatgccga taatgccgcc ttcgttgacc ggctgtagca
     2701 aacgcgctac gcggatcgcc tcgccgcgat actcggtatg atagaaccac gccagcgccg
     2761 gataaagccg ggtacggggc gtagcgggcg gcatggcagg cagatcgtca taaccggaaa
     2821 tgaccttccc ggaagggtcg acgactttgt aatagagtcg atcattcata ttaagctcga
     2881 agctatccag caccacccag ggcacgttaa cttccagatg gttattgcgc accaccagcc
     2941 gttccgatac cgttcgcgcc gaggagagca acgtacgatc ataagcctga gtggcggcct
     3001 gtagcgcatt gacataactg ttaaacgccg acagccccca tagcagaatc agcggcaacc
     3061 ccaggaacag taagagttgc aggtacaacg attgcggctt aacccacttc atcgccgcgc
     3121 tccagcacat aacccaggcc gcgcagcgtc gtaattcgta catcgcttcc ctgaagtttt
     3181 ttacgcagtc gatgaatata aagttcgatg ctttcagggc ttacctcatc gttcaggctg
     3241 aacacctgtt caaaaagctg ctgacgcgag acaggccgcg ttcgtcggta catcaatacg
     3301 gttaagagcg cctgctcacg cggcgtcagc gctaacggct gtccctgtaa cagaaaatac
     3361 ccttcatcat gaaagatcaa ttcacccagt tgctgaactt catgaaccag cccagcgctg
     3421 cgtcggagca aggcccgtaa acgggcatcc agctcttcca gttcaaaggg tttcggcaga
     3481 tagtcatccg cgccgacgtt gagacctttt acgcgatccg ccaccgcgct tcgcgccgtg
     3541 agcagcaaaa cgggcaaggt ctgaccgcgt ttacgcagcc gttgcaccac ctccagtcca
     3601 tccattcccg gcatattgat atccagcacc atcagcgcat acatttcact gtgcagaaga
     3661 tggtcagccg ccaggccgtc aaatacgcag tccacggcaa agccgttttg caccagcgct
     3721 ttctccagcc agtgagccag ctcacggtta tcttccgcca ataagagacg catatcacat
     3781 cctgtaaagt ttctgccgca ttgaaaggga attgaaaggt tattgtttta acaatcacgc
     3841 aaccgaactg ctacatgtcg gctcacataa tcacaaaaat cttcttccga acctgaaaaa
     3901 tccggacgtc cggcgtgagg ataaaaaatg aaaaaacaat tacttcgtac ccttactgca
     3961 agcattttat taatgagtac ctctgttctg gcacaggagg cgccgtcgcg aacggaatgt
     4021 atcgcgccag ccaaacctgg cggcggttcg ctgctcaacc tgtcgcaggg gaaatttggt
     4081 cgctacggcg tggatgatgt gcgctggctg gcaagcgtgg gcactgatta cggcatgatc
     4141 gccgtgcgtg cggattcccc gtggaagacg ctgaaagatc tgatgacggc gatggaaaaa
     4201 gatcccaaca gcgtggtcat cggcgctggc gcctctattg gcagccagga ctggatgaag
     4261 tcggcgttgc tggcgcaaaa ggcgaacgtc gatccgcaca agatgcgcta cgttgccttt
     4321 gagggcggcg gcgagccggt gacggcatta atgggcaacc atgttcaggt tgtctccggc
     4381 gatctcagtg aaatggtgcc ttatctgggc ggcgacaaaa tccgcgtcct tgccgtcttt
     4441 tcagaaaatc gtctgctggg ccagcttgcc aatgtcccta ccgctaaaga acagggctac
     4501 gacctagtgt ggccgattat tcgcggcttc tatgtcgggc ccaaagtcag cgatgccgat
     4561 taccagtggt gggtggatac cttcaagaag ctccagcaaa ccgacgagtt taaaaagcag
     4621 cgcgatctgc gcggcctgtt tgagttcgac atgaccggcc agcagctcga tgactacgtg
     4681 aaaaaacagg ttactgatta ccgtgaacag gcgaaagcct tcggactcgc gaaataatcg
     4741 cggaggcaat gatgagcgat cgtatctttg cgggtatctg gctgttgctc tgtatcgccg
     4801 ggctattcat cgcctggcag atccaaagcg aatacagcta tgaacccgtc ggcccccgcc
     4861 cttttccgct ggggattatc ggcctgatgg cgctctgcgc gctggcgctg ttattgcgcc
     4921 atcccgacac ggtgagctgg ccgcgccgcc atgttctgca aaagctaatt accatgatca
     4981 tcatcctgtt gatgtatgcc tggggattcg aatggctggg ttttcccatc gccaccgcgc
     5041 ttctcaccat ggttatcggg atgctgttcg gcgccacgat tccggcggcg ggtatctccg
     5101 gcgcggtatt aggcattctg ctgtggtatg cctttgaccg gctgcttgat gtcaccttac
     5161 ctctcggcgc ctggctgagt taacggagca acgatggata cctggatatg tctttctcag
     5221 ggctttgcgg tggcaatgac gccggaaaac ctggttatcg cgttgattgg ctgcttcgtg
     5281 ggcacgatcg tcggtctgct gccgggcctg ggaccgatca acggcgtggc aatcttactg
     5341 ccgctggcct ttgcgttgca tctgcctgcg gagtcggcgc taattctgct ggcgacggtg
     5401 tacattggct gtgagtatgg cggcaggatc tcctccatat tgctcaacgt ccccggcgat
     5461 gcggcggcga tcatgacggc gctggacggt tacccaatgg cgcagcaagg gaaaggcggc
     5521 gtagcgctgt cgatttccgc agtcagctca tttttcggtt cattaatcgc tatcggcggc
     5581 atcattctgt tcgccccttt actggcgcaa tggtcgctgg ccttcggtcc ggcggaatat
     5641 ttcgccttaa tggtttttgc tatcgcctgt cttggcagca tgatggcgca aaacccgctt
     5701 aaatcatttc tggcagctct gatcggtctt ggccttgcga ccgtcggcgt ggacgccaac
     5761 accggggttt atcgctttac ctttgacagc gttcatcttt ccgacggcgt acagtttatc
     5821 gtcgtggtga tcggcctgtt ctcggtatca gaaatacttt taatgctgga acataccagc
     5881 agcgggcaaa caatggtccg caaaacgggt cgaatgttgt tcaacctgaa agaaggcgcg
     5941 cagtgtatcg gcaccaccct gcgttcttcg gtaatcggct tttttgtcgg cgtattgccc
     6001 ggcgccgggg cgaccattgc cagcgccatt acctatatga ccgagaaaaa actcagcggc
     6061 aacagcgata gcttcggcaa aggggatatt cgcggcgtcg cggcgccgga ggcggcaaac
     6121 aacgcctctg cctgcggctc cttcatcccg atgctgacgc tgggcgttcc cggttccggc
     6181 actacggcag tgatgatggg ggcgctgacg ctgtataaca tcacgccagg cccggcgatg
     6241 ttcaccgaac agccggatat cgtctgggga ctcatcgctg cgctgctgat tgcgaacgtg
     6301 atgctgctga tcatgaatat cccgttgatc ggtctgttca cccgtatgct caccattccg
     6361 ctgtggttcc tggtacccgc catcgctgcc gtatcggcgg taggggtata tgcggtacac
     6421 agccctacct tcgatctggt gctgatggtc gcgcttggcg tgttagggta cattttacgt
     6481 aaaatgcact tccccatgtc gccgctgatc ctgggatgcg tactggggga aatgctggag
     6541 cagaacctgc gtcgcgcact ctccatcagt aacggcaata tggcgatttt gtggcaaagc
     6601 ggcgttgcca aagccctgct gatcatggcg atcatagtca ttgtcgtacc gccagtgtta
     6661 cgtctgatcc gtaaacacag ccgtaaaccg caggttgacg ccagttaatt gactgctgaa
     6721 atacgttgta cttgtccggc ctacgcgctc atgtgccagg ccgggcaacc ccgccagcat
     6781 cactctttcc ataactcgct cattttacac cccttcttgc cgttgtcagg ctcgtggcgc
     6841 cgttaacctc acctttcgca ttgttaaata tttgttgttt ttgatcacaa taattaaaca
     6901 aaagcggtta tttcatacgc gttcctggaa aatgtcgata tttttaattt atggctacga
     6961 aatgagcatc gccatgtctc cctgaccatc taccgagagg aatgattctg atgaatgcac
     7021 tgactgccgt aaaagcgaac acagatgatt tagcccaacg ccatactggt ttcatccttg
     7081 ccccttcggc gcagtcgccg cgcctgctgg cgttaacgtt tacggcggat accacaagac
     7141 aatttctcca tcaggttgcg cagtggccgg tgcaggcgct ggaatacaaa tctttcttac
     7201 gtttcaaaat cggcaagatc ctcgacgatc tgtgcggcaa tcagctacaa ccgctgttga
     7261 tcaaaacgct cctcaaccgt gcacaaggcg cgctgttgat cagcgccgaa gggatcgatg
     7321 atgtcgcaca ggcagaagag atggtcaaac tggcgacggc ggtggcgcat cttattggtc
     7381 gctccaacta cgatgcgatg agcggccagt attacgcgcg tttcgtggtc aaaaacgtcg
     7441 acaactccga cagttatctg cgccagcccc accgcgtaat ggaactgcac aatgacggta
     7501 cctatgttga ggaggtgacc gactacgtgc tgatgatgaa aatcgacgaa caaaatatgg
     7561 aaggcggtaa ttcgctgctg ctgcaccttg atgactggga acatctggag tcgtttttta
     7621 cccatccgct ggcgcgtcgc gtcatgcgct gggcggcgcc gccaagcaag aatgttagcc
     7681 atgacgtctg gcacccggtg tttgatgtcg accaacaagg ccgcccggtc atgcgttata
     7741 tcgaccagtt cgtccagcca aaagactttg aagaaggcgt ctggctcagc gagctttcag
     7801 acgcgctgga aaccagtcaa aacatcctct ccgtgccggt accggtcggc aaattcctgc
     7861 tgattaacaa tctgttctgg ctacatggac gcgatcgttt tacgccgcat cctgacttgc
     7921 gtcgcgagct gatgcgccag cgcggttact tcgcctacgc cgccagccat tatcaaactc
     7981 accaataagc gccacggcga aggaattacg cggatgtatg attttgtgat tatcggcggc
     8041 ggcattatcg gcatgtcgac cgccatgcaa cttattgatg tctacccgga tgcgcgcatc
     8101 gcgttgctgg aaaaagagtc cgcgccagcc tgccaccaga ccgggcataa cagcggcgtg
     8161 atccatgccg gggtgtacta cacgcccggc agcctcaaag cgcggttttg tctggcgggc
     8221 aatcaggcga ccaaaacctt ttgcgatcaa aacaacatcc gctacgacac ctgcggcaaa
     8281 atgttggtcg ccacctcgga gctggaaatg gcgcggatgc gcgcgctatg ggagcggacg
     8341 gcggccaacg gcttagagcg cgagtggtta aacgcggcgg agctgcgtga acgcgaaccc
     8401 aatatcattg gcctgggcgg gatttttgtc ccttccagcg ggattgtcag ctatcgcgat
     8461 gtcgcgacgg ccatggcgaa ccgctttcag gccaaaggcg gcgagatcat ctaccatgcc
     8521 gaggtcagcg cgctaacaga acatgccgct ggcgttatca ttcgcacttc gcaaggccga
     8581 gaaatcgaaa ccgctacgct tatcggctgt gcagggctga tggcggatcg gctggtcaaa
     8641 atgctgggcg tggagcccgg ttttattatc tgccctttcc gcggcgagta ctttcgtctg
     8701 gccccgcgac acaaccggat cgttaaccat ttgatctacc cgatccccga tccggcaatg
     8761 ccgtttctcg gcgtccacct tacccgcatg atcgacggca gcgtcacggt cgggccgaat
     8821 gcggtgctgg cgcttaaacg cgaaggctac cgtaagcgcg acgtttcctt caccgacacc
     8881 ctggagattt tccgctccgc cggcattcgc cgcgtactgc aaaaccatct gctttccgga
     8941 ctgggcgaga tgaaaaactc gctgtgcaaa agcggctatt tgcggcgagt acaaaagtat
     9001 tgccccagcc tgaccgtcaa cgatctccag ccctggccgg caggcgtgcg ggcgcaggcg
     9061 gtttcgccgg acggcaaact gattgatgat tttctgtttg tcacgacgcc gcgttccatt
     9121 cacacctgta acgcaccctc cccggcggcg acatcagcga tacctatcgg cgcgcatatc
     9181 gtcagtaaag ttcaggcgct acgcgcaagc cagagcaacc ccggacgtac gctgcgtgcg
     9241 gcacgcagcg tggacgcatt acacgccgca tttacccgtt aacccttcag acaggaagca
     9301 attatgcaac ttaacgactc taccctgttc cgccagcagg cctttatcga tggcgactgg
     9361 cgcgacgcgc gcggcggcga tgtcatcccc gtgagcaacc ccgccaacgg gaaaccgctt
     9421 ggcaatgtgc ccaaaatggg ggcggaagag acgcgcgacg ccatcaacgc cgccaatcgc
     9481 gccctgcccg cctggcgcgc gctcaccgcc aaagagcgag ccaatatcct gcgtcgctgg
     9541 ttcaatctga tgatggaaca tcaggacgat ttggcgcgtc tgatgacgct ggaacagggc
     9601 aaaccgctgg cggaagcgaa aggcgaaatt agctacgccg cctcgtttat tgaatggttc
     9661 gccgaagagg ggaagcgtat ctatggcgac acgattccag gtcatcagac cgataaacgg
     9721 ctgctggtga ttaaacagcc catcggcgtc accgccgcga ttaccccgtg gaactttccc
     9781 tcggcaatga tcacccgtaa agccggcccc gcgctggccg caggctgcac aatggtactc
     9841 aaacccgcca gccagacgcc gttttccgcg ctggcgctgg cggaactggc ccagcgcgcc
     9901 ggaattctcg caggcgtatt taacgtcgtt accggttcgg caggcgatat cggcggcgag
     9961 ctgaccagca acccgctggt acgcaaactg tcgtttaccg gctcgacgga gattggccgc
    10021 cagctaatgg aacaatgcgc caaagacatt aaaaaagtat cgctggagtt gggcggcaat
    10081 gcgccgttta tcgtctttga cgatgccgat ctggataaag ccgtcgaggg cgcgctggct
    10141 tcgaagtttc gcaacgccgg gcagacctgt gtctgcgcca atagattgta tgttcaggac
    10201 ggcgtttacg atcgttttgc ggaaaaactc aaccaggcgg taaataagct cgcggtcggc
    10261 gacggcctgc aagccgacgt cgctatcggg ccgctgattg atgaaaaagc cgtggctaaa
    10321 gtccaggagc atatcgccga cgcgctggaa aaaggcgccc gcgtaattac gggcggtgaa
    10381 gcgcacaaat taggcggcaa cttctttcaa ccgaccattc tggcggatgt tcctgataac
    10441 gcgaaagtcg ccaaagaaga gacattcggg ccgctcgcgc ctctgttccg cttcagcgac
    10501 gaggcggatg tcatcaggca ggctaacgat accgagttcg gcctggcagc ctatttttat
    10561 gcacgcgatt taagccgcgt tttccgcgtc ggcgaagcgc tggaatacgg catcgtcggt
    10621 attaataccg gcattatctc caacgaagtc gcgcctttcg gcggtattaa ggcctccgga
    10681 ttaggccgtg aaggttccaa atacggcatc gaagattatt tagaaatcaa atatatgtgc
    10741 atcggccttt aacaggagag tcgctaatga ataccaataa cactttaatg cagcgctgtc
    10801 ataacgccgt tcctcgcggc gtgggccaga ttcacccgat tttcgccgag cgggcggaaa
    10861 attgtcgggt ctgggatgtc gaaggccgtg agtatctcga tttcgcgggc ggcattgccg
    10921 tcctgaacac cggtcattta catccgggca ttgtttcagc ggtcgaagcg cagttgaaga
    10981 aattgtcgca tacctgtttt caggtgctgg cctatgaacc gtacctggcg ctgtgcgaac
    11041 gcatgaacca gaaggtaccg ggcgatttcg ccaaaaaaac gttgctggtc acgaccggtt
    11101 cagaagcagt tgaaaacgcg gtgaaaatcg cccgcgcggc gacaaaacgc agcggcgcta
    11161 tcgcgtttag cggcgcttac cacggtcgta cccactacac gctctctctg accgggaaag
    11221 tacacccgta ctctgcgggt atgggattga tgccaggcca tgtctaccgc gcgctttatc
    11281 cttgcccgct acacaacatc agcgacgacg acgcgatcgc cagcattgaa cgcatcttta
    11341 aaaatgatgc cgcgccggaa gatatcgccg ccattattat tgagccggta cagggcgaag
    11401 gcggatttta cgccgcctct cccgcgttta tgcagcgact gcgcgcgcta tgcgaccaac
    11461 acggcattat gttgattgcc gacgaagtgc aaagcggcgc gggccggacc ggtacgctgt
    11521 tcgccatgga acagatgggc gttgcggcag atattaccac gtttgcgaaa tcgatcgccg
    11581 gcggctttcc gctggcaggc gttaccggcc gggcagacgt gatggacgct atcgcgccgg
    11641 gcggtctggg cggcacctat gccggaaacc cgattgcctg cgtcgccgcg ctggcggtac
    11701 tggacatttt cgagcaggaa aatctactgc aaaaggcgaa tacgcttggc aaaacgctgc
    11761 gcgatggcct gatggagata gcggaaacgc accgtgagat tggcgacgtg cgcggactgg
    11821 gcgccatgat cgccattgag ttgttcgaaa atggcgaccc cggcaaaccg aacgcgactc
    11881 tgaccgccga cattgtggcc cgcgcccgcg agaaagggtt aattctgctc tcctgcggtc
    11941 cttactacaa catcttgcgc atcctcgttc cactcactat tgaggcctcg cagattcggc
    12001 aaggcctgga gattatcgcc cagtgctttg atgaggcgaa acaagcgtaa tgtccaataa
    12061 gcagcgtcgg atggcgacgt aactgtctta tccggcctac aaaaaccgtt tcgattgtag
    12121 gccgaataag ccaggcacca tccggtaaac gagcgcaata acaataaaga ggttttagga
    12181 tggggcaatt gtcagaatca catgcattag ggggcgggct gaaatcacgc cacgtcacca
    12241 tgttatcgat cgccggcgtc atcggcgcca gcctgtttgt cggttccagc gtggcgattg
    12301 cggaggccgg ccctgcggta ctgctggcct atctgttcgc aggactttta gtcgtcatga
    12361 ttatgcgaat gctggctgaa atggccgtcg ccacaccgga taccggttct ttttccacct
    12421 atgcggataa agcgatcggc ccctgggccg ggtataccat cggctggtta tactggtggt
    12481 tttgggtgct ggttattccg ctggaggcca atattgccgc cattattctg aattcatgga
    12541 taccgggtat tccggtgtgg ctattttcat tagtgattac gcttgcctta accggaagca
    12601 atttattgag cgtcaaaaat tacggtgaat tcgaattctg gctggcgcta tctaaagtaa
    12661 ttgccattct ggcgtttatc gcgctgggcg cggcggcgat tagcggtttt tatccgtatg
    12721 ccggggtaag cggtatttcc cggctctggg atcacggcgg ttttatgcct aacggcttcg
    12781 gtgcggtgtt aagcgccatg ttgatcacca tgttctcttt tatgggcgcg gaaatcgtca
    12841 ctattgctgc cgcggaatcc gatacgccgg ataaacatat cgtacgcgcc accaattctg
    12901 ttatctggcg aatttccatc ttttacctgt gttccatttt tgtggtagtg gcgctgatcc
    12961 cgtggaatat gccgggtctg aaaagcgtag gttcgtaccg ttcggtactg gagctgcttc
    13021 atattccgca cgcaaaattc attatggact gcgtgatttt attgtcggtg accagttgtc
    13081 tgaactccgc attatatacc gcctcccgga tgctctattc ccttagccgc cgcggcgatg
    13141 cgcctgcgat aatgggaaaa actaaccgta gcaaaacgcc ctgggtggcg gttctcctct
    13201 ctaccggcgc ggccttttta accgttatcg tcaattatta cgccccggca aaagtgttta
    13261 aatttcttat cgacagttcc ggcgccatcg cgctgctggt ctatctggtg attgcgattt
    13321 cgcaattgcg gatgcgtaaa attctgctgg cgcagggcgg agaaattaag ttgaaaatgt
    13381 ggctttatcc gtggctcacc tggctggtta tcggctttat ctgctttgtt ctggtggtga
    13441 tgctatttcg accggcacag caactagaag tcatttcaac ggggctgtta gggctgggca
    13501 taataggtac tgtccccatt atgtctcgct ggaaaaaact gataaggtgg caaaaagccc
    13561 ccctgcaaaa cctacgttag ttattcccgg cgtcagccgg gaagcttctc aggagtaaaa
    13621 gatgaccgcc ctttcccaac cgacggccat agatggctat cgctggctta aaaatgacat
    13681 tattcgcggc acttatcagc cggatgagaa actgcggatg agtttattaa ccgcccgcta
    13741 tgcgctcggc gtagggccgc tgcgcgaggc gctgtcacaa ctggtggcgg aacggctggt
    13801 caccgtggtg aatcaaaaag gctatcgcgt ggcatccatg tcagaggcgg aactcctcga
    13861 tatttttgac gcgcgcgcca atatggaagc gatgctggtg cgcctggcga ttgaacgcgg
    13921 cgatgatgcg tgggaggcgg agatcctggc gcgagcgcat atgctcagta aactggaagc
    13981 cagcgatgcc agtgaacata tgctcgatga atgggatcag cgccaccagg cgtttcattc
    14041 cgccattgtc gccgggtgcg gctcccacta tctgctacag atgcgcgaac gcttatttga
    14101 cctggcggcc cgctaccgct ttatttggtt acgtgaaacc gttctgtccg tcgagatgct
    14161 ggaagataaa catatccagc atcacacgct aaccgaagcg atactggcgc gcgaggcggc
    14221 acgcgccagc gaattaatgc gtcagcattt gctgacgccg attcccatta ttcgccaggc
    14281 gatggcagga aaaatgtagc caggcacggc ctgatagcca ttattcttca ggaatacgca
    14341 acacttgtcc cggatatatt ttttccgggc ttttcagcat cggtttattt gcctcgaaga
    14401 ttttattata cagattggcg ttaccataca cttgctttga aatagcgctc agggtgtcgc
    14461 ctgattttac ggtataaaac tgactttcag ccgctggcgt cgtggtttta acctgatcgt
    14521 caacgctgct aatcccggcg atattcccca cggcaaccag aattttttct tttgcctcct
    14581 gactcagccc atcacccgtc actgtcgctt ttccatcagc aatttgcaca ttcactttgt
    14641 cagcgtcggg tattcccgtt ttatttaaat gttcctagac ttttttcgcc tgatcgtcct
    14701 tatcatgatt agcggttacc gcgtcccaga gtttttcacc tgcatctttt acaaaattga
    14761 aaagtcccat attcacctcg cttgtcaaaa atacacacaa agaaaagtgt agcagaggga
    14821 atgaggttat cctgataagc ggcgcttatg cgccgccggt ggccggtaat taatgacgca
    14881 tctgaaccca aaatgcatgg ataagccccg gaatatatcc gagtaatgtc agcaggatat
    14941 taaggataaa tgcccaaccg aacccttttc ctaaaagtac gccgagcgga ggcaaaataa
    15001 tcgtaaatac aattctccag aaacccatat acactccata caagcaaaat tagtcattgt
    15061 ttaaaaagag attttatctc taagcatagt cagtttacct gagcctgcca gtcgcgcgcc
    15121 gcgcttttac cctcctttac gctttttacg ctggcatcag gttgacgttt attttagaat
    15181 taactaaatt tagaaaacac ttaaataact atgacagagc ttgaaaaact tcaggccagc
    15241 gcagaacagg cagcggccct gctcaaagcg atgagccacc caaaaagatt actgatttta
    15301 tgtatgcttt gcggttcacc aaaaaccagc gcaggcgaac tggcgcgcat taccgggcta
    15361 agcccctccg cgacgtcgca gcatctggcg cggatgcggg aagaagggct gattgatagt
    15421 caacgcgatg cccagcgcat tcactatttc attaaaaatg aggcggttaa tacgcttatc
    15481 gccacgttaa agaatctcta ttgtccataa ggaggcacga tgtccattgg gatagtttcc
    15541 ccccgtgagg cgcaagcgct gatagcgcaa ggcgcgaaac tgattgatgt gcgcgacgcc
    15601 gatgaatatc tgcgcgagca tattccacat gcgcaactgg cgccgctttc ccggcttgaa
    15661 cagggcgatt tgcccgccaa cctgcgagcg gaacagatta tttttcactg tcagtcaggt
    15721 aaacgaacca gcagcaatgc agcaaaacta caggccattg ccgcccctgc tcaagtcagt
    15781 ttactggaag gcggtatcga cggatggaaa gcggcaggat tgcccgtcac agaagacaaa
    15841 tcgcaaccgt tgccgctgat gcgtcaggtg caaatcgccg ccggcgggtt gacgttgctt
    15901 ggggtgattc tgggctatac ggtccacggc ggctttttcc tcattagcgg ttttgtcggg
    15961 gccgggttaa tgctggcagg cataaccggc ttctgcggaa tggcgcgact actggaaaaa
    16021 atgccctgga atacccgtac tcattaagcg gtactttcac cgcgcgtcgg taagtgtgta
    16081 gtagactgaa ggcgggttta taccattgtt caacgggagg acgtgatgtt cacaccaggc
    16141 gatatcgtac agccccgaat ggggggggcc gaaactgaaa gtgattgaag tcaacgagga
    16201 tcatattgtc gcggtacagg tcggtaatga gccgggcgaa aaattgatcc tcaaagcggc
    16261 agatgtcacc ccctattgcg aaaagggcga ttttggcgtg tgctgattta tcaaaatgag
    16321 catggcgcaa cgttccctga atcccggtta atagagacag gaaacgcagc gccatctgtt
    16381 aaaggttatc cgtgattaga ttaagaaatc atccagagat ttccccgccg ccagcgcctg
    16441 ggcaatcggt ttaggcgtac gaccttgtcc ggtccaggtt ttttcttcgc cattgaaatc
    16501 agtaaaacga tattttgccg gacgcggttg gcgcttttta gcagaacgcg gcattgctga
    16561 atccatggca aataactctt ccgggttaat accgtctgct ttcatcagct ccagaaaggc
    16621 attaattttc tcctgcttct cggcaagctg gcgttgctgc aattcttctt cttcgcgtct
    16681 ttctttagtg acaaccctga atttttcgag catttcttca agaacgtcaa tggagaattc
    16741 gcgagccata gcgcgcagcg tgcggatatt atttaagttc tgtaacatca aattcatatc
    16801 aataaaaacc ttttaacgca gaaaacaaaa actattacag gcggtattgt atgcgattat
    16861 tgattatatt tccagatcct aaagttcata cagatataca cagcataact cgattaatta
    16921 tattaatctg ttaaccagaa gattatattc attaccccct gtgtgtttca ggttattctg
    16981 cctacggtat atctgtaggt ttcccgttcg gctgtttata gcgtat
//
LOCUS       DAJVKX010000093        16854 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000093 DAJVKX010000000
VERSION     DAJVKX010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16854
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.093"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(138..3251)
                     /gene="acrD"
                     /locus_tag="OPY25_003137"
     CDS             complement(138..3251)
                     /gene="acrD"
                     /locus_tag="OPY25_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HCS0928689.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGALAIFSLPVEQYPDLAPPNVR
                     ITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQATITLSFIAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQDQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPQQFRDITLRVNQDGSEVKLGDVATVELGAEKYD
                     YLSRFNGNPASGLGVKLASGANEMATAKLVLDRLNELAQYFPHGLEYKIAYETTSFVK
                     ASIIDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAMILTPALCATLLKPLHKGEQHGQ
                     RGFFGWFNRTFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPTSFLPQE
                     DRGMFTTSIQLPSGSTQQQTLKVVEKVENYYFTHEKNNIMSVFSTVGSGPGGNGQNVA
                     RMFVRLKDWDARDPTTGSSFAIIERATKAFNQIKEARVFASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARDQLIELAGKNSSLTRVRHNGLDDSPQLQIDIDQRKAQALGVS
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAKYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDVMESLVHQLPGGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHALLDATLYASRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLIRRRF
                     PLKPRPE"
     gene            complement(3436..5136)
                     /gene="narQ"
                     /locus_tag="OPY25_003138"
     CDS             complement(3436..5136)
                     /gene="narQ"
                     /locus_tag="OPY25_003138"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HCS0928690.1"
                     /translation="MTVKRPVSASLAKAFFYIVLLSILSTGSALLTLTSSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSRSPQINAHRQLFQHALNSPVLQNLNAWYVPQAVKTRYARL
                     HANWLEMNSRLQDGDIVWYQSNINNYVDQIDLFVLALQHYAERKVMLVVAISLAGGIG
                     IFTLVFFTLRRIRQQVVRPLNQLVTASQRIEHGQFAPLPLDTSLPNELGLLAKTFSQM
                     SSELHKLYRSLEASVEEKTHDLHEAHRRLEVLYQCSQALNTSQIDVHCFRHILQIVRE
                     HDAAWYLELTVGDNWRISEGTQSPDLPMQMLPVTMQDTVYGELHWQSPNVNASTPLLN
                     SVSTMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRAIP
                     EDNAGAQSIMADFSRALNDAYRQLRELLTTFRLTLQQADLPSALHEMLEDLQSQTPAK
                     LKLDCRLPTLALDAQMQVHLLQIVREAVLNAIKHANASEIAVSCVTAPDGDHTVYIRD
                     NGIGIGEPHEPAGHYGLNIMRERAERLGGTLNFSQPSGGGTLVSISFRSSNKEESQLT
                     "
     gene            5322..7181
                     /locus_tag="OPY25_003139"
     CDS             5322..7181
                     /locus_tag="OPY25_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase FeS-binding subunit"
                     /protein_id="HCS0928691.1"
                     /translation="MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTPQRYQPRITV
                     IKHQRQRSAVTCHHCEDAPCARSCPNGAIAHINDSVQVNAQKCIGCKSCVVACPFGTM
                     QMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
                     TARQEIRPWHTVDTQHSGTACSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAA
                     QAEREAARCLTCGEHSICEWTCPLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITG
                     RVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDLSDVQKSDKRVAIIG
                     AGPAGLACADVLARRREIFSAMGIRFELNCEVGKDISLETLLESYDAVFVGVGTYRSM
                     KADLPNEDAPGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTAMDCV
                     RTALRHGAANVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVELVLDTHGRASG
                     IRFLRTRLGEPDGQGRRRPVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHGVKVDNW
                     GRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGILDWLAK"
     gene            complement(7630..8928)
                     /gene="pbp4b"
                     /locus_tag="OPY25_003140"
     CDS             complement(7630..8928)
                     /gene="pbp4b"
                     /locus_tag="OPY25_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HCS0928692.1"
                     /translation="MKFTLVATVLLTFSLSAFAVEYPVLTTASPDQVGFDSQKLHRLD
                     GWIQNQIDAGYPSINLLVIKDNHIVLQKAWGYAKKYDGSTLLAHPIRATTNTMYDLAS
                     NTKMYATNFALQKLVYEGKIDVNDLVSKYIPGFKDMPGDKIKGKDKLRIIDILHHVAG
                     FPADPQYPNKNVAGKLFSQSKSTTLEMIKKTPLEYQPGSKHIYSDVDYMILGFIIESI
                     TAMPLDRYVETTIYKPLGLKHTVFNPLMKGFTPPQIAATELHGNTRDGVIHFPNIRTN
                     TLWGQVHDEKAWYSMGGVSGHAGLFSDTHDMAVLMQVMLNGGGYGNVKLFDNKTVAQF
                     TRRSPEDATFGLGWRVNGNASMTPTFGVLASPQTYGHTGWTGTLTSIDPVNHMAIVIL
                     GNRPHSPVANPKVNPNVFVSGLLPAATYGWIVDQIYGSLK"
     gene            9132..9707
                     /gene="nudK"
                     /locus_tag="OPY25_003141"
     CDS             9132..9707
                     /gene="nudK"
                     /locus_tag="OPY25_003141"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HCS0928693.1"
                     /translation="MSQTITLIKDKILSDNYFTLRNITYDLTRRNGEVIRHKREVYDR
                     GNGATILLYNSTKKTVVLVRQFRVATWVNGNQDGMLIETCAGLLDNDEPEVCIRKEAI
                     EETGYDVGEVRKIFELYMSPGGVTELIHFFIAEYHDSERASIGGGVEDEEIEVLELPF
                     SRALEMVRSGEIRDGKTVLLLNYLQTSHLMD"
     gene            9832..10875
                     /locus_tag="OPY25_003142"
     CDS             9832..10875
                     /locus_tag="OPY25_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HCS0928694.1"
                     /translation="MRYRVILFCLFGLLPVQLLWAAPAQRTFSDWQVTCNNQNFCVAR
                     NTGEHHGLVMTLSRSAGARTDAVLRIDRGGLAPPDAKEAAIAPRLLLDGKPLSFNSSH
                     WRVSPWHLMTGDPATITAFLQTIQDAQAITLKNGVQTLSLAGLKAALLFIDAQQKRVG
                     SETAWIEKGNEPPLSVPPAPALKGIAVINPTPVPLSEEERDDLLDYAAWRVNGIRCSL
                     DPLRRETQVSALTDDKALLIVNCEAGAYNTIDLAWVVSRKKTLVSRAVRLRLPFNRGV
                     ESNDMELMNAFFDEKTRELVTLAKGRGLTDCGIQTRWRYDGDRFRLVRYAEEPSCDSW
                     HGPDAWPTLWITR"
     gene            11003..11233
                     /locus_tag="OPY25_003143"
     CDS             11003..11233
                     /locus_tag="OPY25_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928695.1"
                     /translation="MKINNGPVLCPHCGCLSAYYEIDRLAAIREKVNKEGGSAAWDST
                     LQAHKKKAFCLMCHKSIDEVVIGQSDAPESTK"
     gene            complement(11296..13296)
                     /gene="tkt"
                     /locus_tag="OPY25_003144"
     CDS             complement(11296..13296)
                     /gene="tkt"
                     /locus_tag="OPY25_003144"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCS0928696.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNSHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLGAQFNRPDHEIVDHYTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVVHDIDGH
                     APEAVKKAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEESHGAALGEEEVALTRQKL
                     GWHHPAFEIPKEIYRAWDGREKGEKAQQQWQEKFAAYEKAYPELAAEFTRRMSGGLPE
                     AWESATQKFINDLQANPAKIATRKASQNTLNAYGPLLPELLGGSADLAPSNLTIWKGL
                     TSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAMEQLASLRLTPNFSTWRPCDQVEAAVGWKLAIER
                     QHGPTALILSRQNLAQVERTPEQVKAIARGGYILKDSGGKPDIILIATGSEMEITLQA
                     AEKLTGEGHNVRVVSLPSTDIFDAQDEAYRESVLPAHVTARVAVEAGIADYWYKYVGL
                     KGAIIGMTGYGESAPADKLFPYFGFTVENIVEKARRVLNIKG"
     gene            complement(13316..14266)
                     /gene="tal"
                     /locus_tag="OPY25_003145"
     CDS             complement(13316..14266)
                     /gene="tal"
                     /locus_tag="OPY25_003145"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HCS0928697.1"
                     /translation="MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGL
                     EQYGHLIEDAIAWGKKHGGTQEQQVAAASDKLAVNFGAEILKSIPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSF
                     AQARACAEAGVYLISPFVGRIYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYE
                     TIVMGASFRRTEQILALTGCDRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMT
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            14538..16817
                     /gene="maeB"
                     /locus_tag="OPY25_003146"
     CDS             14538..16817
                     /gene="maeB"
                     /locus_tag="OPY25_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HCS0928698.1"
                     /translation="MDEQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLAAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFINVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGMQKHNIVV
                     CDSKGVIYKGREPNMAETKAAYAVDDSGKRTLDEVIDGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMDSGVATRPIADFDAYIDKLTEFVYKTNLFMKPIFSQARKDPKRVVLPEG
                     EEARVLHATQELITLGLAKPILIGRPSVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWSEYYQIMKRRGVTQEQAQRAMIGNHTAIGAIMVQRGEADAMICGTIGDYHEHFSV
                     VKAVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNEDPTPEQLAEIAVMAAETVRRFG
                     IEPKVALLSHSNFGSSNSLSASKMRETLERVRERAPDLMIDGEMHGDAALVESIRNDR
                     MPDSPLKGAANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVSKPVHVLTPIASV
                     RRIVNMVALAVVEAQTTPL"
BASE COUNT         3898 a         4428 c         4629 g         3899 t
ORIGIN      
        1 tggaaagatt ttatcgaagt cattcttcgt aaataaatgc ctggaaggca ccgcgctccc
       61 ataggggata agaaaaggcg actcagcgaa agtcgccttt tttgtgcccg acacctcgta
      121 tcaggctggc caggagctta ttccgggcgc ggcttcagcg ggaagcggcg acgtatcagc
      181 acgaaaaaca ggggtacaaa gaagatagcc agaatggttg ctgagatcat tccccccatc
      241 acgccggttc cgacagcatg ttggctaccc gagcctgccc cggtgctggt ggccatcggc
      301 aatacgccaa agataaacgc cagcgaagtc atcagtatcg gtcgcaggcg ctggcggctg
      361 gcgtacagcg tggcgtctaa cagcgcgtgt cccttctgat tcatttcgtt ggcgaattcc
      421 acaatcagaa tcgcgttttt cgccgagagg ccgataacgg tcaacagccc cacctggaag
      481 taaacatcgt tttccagccc gcgcatccag gtggcgagta acgcgccgat gaccccgagc
      541 ggcacaacca gcatcaccga gaagggcacc gaccagcttt catacaatgc cgccagacac
      601 aggaagacga ctaatagcga aatagcgtac agcgcaggcg cctgcgcgcc ggagagccgt
      661 tcctggtaag acatggctgt ccattccagg ccaaaaccgc ccggtagctg atgcaccaac
      721 gactccatga catccatcgc cgtcccggta ctgacccccg gcgcggcctc tccgacaatt
      781 tctaccgccg aatagccgtt atagcgttcc agacgcggcg atccggtttc ccagcgcgag
      841 gtggcgaagg cggagaaggg gaccatgccg ccgtctttgt tacggacata ccaaagatta
      901 atatcgtccg gcaacatacg atatttcgct gcggcctgaa catagacctt cttcacgcgg
      961 ccccggtcca taaagtcgtt gacgtagctc gatccccagg ctgtttgcag ggtgtcgttg
     1021 atatcgtcaa tcgatacgcc cagcgcctgc gctttccgtt ggtcaatatc aatttgcagt
     1081 tgcgggctgt cgtccaggcc gttgtggcgc acgcgggtca aggaactgtt tttcccggcc
     1141 agctcaatga gttgatctcg tgcggccatc agcgcgtcat ggcctgctcc ggcgtgatcc
     1201 tgtaattcca tatcaaaacc ggcggagctg cccagaccgc taattgccgg cgggctgctg
     1261 gcgaagacgc gagcttcttt aatctggtta aatgcttttg tcgcccgctc aataatggcg
     1321 aacgaggagc cggtggtggg atcgcgcgcg tcccagtctt tcaagcgaac aaacatacgc
     1381 gcgacgtttt gcccgttccc gccagggccg gaaccgaccg tcgagaagac cgacataatg
     1441 ttgtttttct catgggtgaa gtaatagttt tcaacctttt caacgacttt cagggtctgc
     1501 tgttgcgtag agccgctcgg tagctggata gacgtagtga acatgccccg atcttcttgc
     1561 ggcagaaagg aggtggggag acgcaaaaac aggaacacca tgccgccaag caacagaaca
     1621 taaatcagaa tccagcgcag gctgcgatgc aaaattttcg ctacgccttt ctcataacgt
     1681 tcggcattac gattgaaggt acggttaaac cagccgaaaa atccgcgttg cccgtgctgt
     1741 tcgcctttgt gcagcggttt taataacgtt gcgcacagcg ccggcgtcag gatcatggcg
     1801 accagcaccg acagcaccat tgccgagaca atggtgatag aaaactgacg ataaatcgcc
     1861 ccggtggtac cgccaaagaa cgccatcggt acgaataccg cagacagcac catcgcgata
     1921 ccgaccagcg ccccctggat ttgtcccatg gatttgcgcg tcgcttcacg cggcgtgagc
     1981 ccttcttcgc tcatgatacg ttcgacgttt tccaccacca cgatggcatc gtcgaccagg
     2041 agcccgatcg ccagcaccat cgcgaacatg gttaatgtgt taatactgta gccgaacgcg
     2101 taaagcacgg agaaggtgcc cattaatact actggcacgg cgatcgtcgg aatgagcgtg
     2161 gcgcgaaagt tttgcaggaa cagatacatc accaggaaaa ccagcgcgat agcttccagc
     2221 aacgttttga ccacatcgat aatcgaggct ttgacaaagg aggtggtttc atacgcgatc
     2281 ttgtattcca ggccgtgagg gaagtactgc gccagctcgt tgaggcgatc cagtaccagc
     2341 ttcgcggtcg ccatttcgtt cgcgccggag gccagcttaa cgccaaggcc ggaagccgga
     2401 ttgccgttaa aacggctgag gtagtcatat ttttccgccc ccagctccac ggtggcgaca
     2461 tcgcccagtt tgacctcgga accgtcctga ttaacgcgca gggtgatatc gcgaaattgt
     2521 tgcggcgttt gcagcagcga ctgcgcattg atggtggcgt tcagcgcctg cttgtcgacc
     2581 gaaggcgtac cgccaagctg cccgacggcg atttgcgcat tctgcgactc aatcgcatcg
     2641 gtcacgtctt tcgtggtcat ctgaaaacta ttcaatttgg ccggatcgag ccagatacgc
     2701 atagagtact gtgaaccata agcgtcaata tcgcccacgc cgttgacgcg gctgagcggg
     2761 tcctgaatat tactggcgac gtagtcggcg atatcctgct tgtccataga accgtcggta
     2821 gagacgaaag cgatggtcaa aatattggta tcgcccgttt tgcgtaccgt gacgccttga
     2881 tcctgtaccg cctgcggcag tttacgcatc gcggactgta actggttttg cacctgctga
     2941 accgcctcat caggatcggt tcccgcaatg aagctcagcg taatggtcgc ctgtccggtt
     3001 ccgctgcttt gtgatgacat gtacatcaga ttatcgaggc ccgtcatatt ctgctcaata
     3061 acctgggtta cggtattttc cagcgtttgc gccgacgctc ccggataatt cgcggtaata
     3121 cgtacgttgg gcggcgccag atcgggatat tgttcaacag gtaaagaaaa aatggctaac
     3181 gcccctgtca gacacaacag gatagccagc acccaggcaa aaatggggcg atcgataaaa
     3241 aaattcgcca ttaaagggga acctcgtgtt tctacatatc gttatagatt tgaactgctt
     3301 cactgtagcg gcaagctacg agccaaacgt ggagaaataa aggagataat gtaaattatc
     3361 atgcgctttt acagcatact ttttgtgcca acgccggaaa gcctgacatc tggccttccg
     3421 gtgatttgcc gttctttacg ttaactgact ctcttccttg ttggaggagc gaaaactgat
     3481 actgaccagc gtgccgccgc cggagggttg cgaaaaattc agcgtgccgc caagccgttc
     3541 cgcgcgctca cgcattatat tcagaccata gtgtccggca ggctcatgcg gttcgccgat
     3601 accaatgcca ttatcgcgaa tataaacggt atgatcgccg tcaggcgcgg tgacgcagct
     3661 cacggcgatt tcgctcgcgt tggcgtgttt aatggcgttc aggacagctt cacgcacaat
     3721 ttgcaataaa tgcacctgca tttgcgcatc cagcgccagc gtgggtaaac ggcaatccaa
     3781 cttgagttta gccggagtct gactctgtaa atcttccagc atctcatgca atgcggaggg
     3841 taaatcggcc tgctgtaacg tcagacggaa cgtggtgagt agctcgcgaa gctgacggta
     3901 ggcgtcgttc agcgctctgg aaaaatccgc catgatgctt tgcgcgccgg cgttatcttc
     3961 tggaatggcg cgcttcaaaa gcgttaattg aatacgtaaa taagaaagta cctgcgccag
     4021 cgaatcgtgt aactcacggg caatcgtcgc gcgctcttcc attaacaaaa gttgctggaa
     4081 gtgtttttgc gcctgattaa agtacaaacc acgccccagc atcgtggaga cgctgttcag
     4141 caacggcgta gaggcattaa cgttggggct ttgccagtgg agttcgccat agaccgtgtc
     4201 ctgcatcgtc actggcagca tttgcatcgg caggtcgggg ctttgcgtgc cttcgctaat
     4261 ccgccagtta tcgcccacgg ttaactccag ataccaggcg gcgtcatgtt cacggacaat
     4321 ttgcaaaata tggcgaaaac agtggacatc gatttggctg gtattcagcg cctgggagca
     4381 ctggtataac acctccaggc ggcggtgcgc ttcgtgcaga tcgtgcgttt tttcttccac
     4441 cgaggcttcc agcgaacgat aaagtttatg cagctcgctc gacatctgac taaacgtttt
     4501 cgccaacaat cccagctcat tgggtaagct ggtatccagc ggcagcgggg cgaactgacc
     4561 atgttcaatt cgctgactgg cggtgaccag ttgattcagc gggcgaacga cctgctggcg
     4621 aatacgccgt agggtaaaaa agaccagcgt aaatatgccg ataccgcccg ccagcgatat
     4681 ggcgacgacc agcatgactt tacgctcggc gtaatgctgt aacgccagaa cgaagagatc
     4741 aatttgatcg acgtaattgt tgatattgga ctgataccag acaatgtcgc catcctgtag
     4801 gcggctattc atctccagcc agttggcgtg caggcgcgcg tagcgagttt tcaccgcctg
     4861 cggcacatac caggcgttga gattttgcag taccggcgag ttgagcgcgt gctggaaaag
     4921 ttgacgatgc gcattaatct gcgggctacg gctttgcaga tcgtaaccca gccgatagct
     4981 ctgcattcgt agcgaaccgg cgatattgat cgcttcggca tcccgtaaac tgctggtcag
     5041 cgtcagtaat gcgctgccgg tggacagaat agacaacagc acaatataga aaaaagcctt
     5101 agccagactg gccgagaccg ggcgtttaac cgtcacactg gtactccccg catttagctg
     5161 aaccgcaatt tcatttgctt tgaaataaat tgatctgcca caggttctgg acagatagtt
     5221 gtgcttcctg ggcagatgaa cattgccgac cccgccttcg tcagttaata acaatgctca
     5281 tataaagaat aaggtttttg caaccaaaac agaaggacgc catgaatcgt tttattatgg
     5341 ccaatagcca gcagtgtctg ggatgccatg cctgcgaggt cgcctgcgta atggctcaca
     5401 atgatgagcg acatgttctg acgccacagc gctatcagcc ccgaattact gtcatcaaac
     5461 atcagcgcca gcgcagcgcg gttacatgtc accattgcga agatgcgccc tgcgcccgta
     5521 gctgtccgaa cggcgcgatc gcgcatatta acgacagcgt gcaggtcaat gcgcagaagt
     5581 gcatcggctg taagtcctgc gtcgtcgcct gcccattcgg caccatgcag atggtattga
     5641 cgcccgtcgc gccaaaccag ttcaaagcca gcgcgcataa atgcgatctg tgtcagggac
     5701 gtgaacaggg tccggcctgt gtggaaaatt gcccggcgga tgcgctgcaa ctggtcaccg
     5761 aagactcgtt gacccgtctg gctaaaacgc gacggctgcg taccgcccgg caggagattc
     5821 gcccctggca taccgtggat acacaacaca gtgggacagc atgcagcaaa gtcgagcgta
     5881 tgcaggcgac gccgccgcgc ggcgaaccgg ataaactggc gattgaagcg cgtaaaacca
     5941 cctttgagga aatttatctg ccgtttcgcg ccgcgcaggc ggagcgtgaa gcggcccgct
     6001 gcctcacatg cggggaacac agtatctgcg aatggacctg tccgctgcat aaccatattc
     6061 cccagtggat cgaactggtg aaagccggcg atattgatgc ggcggtagag ctttcccacc
     6121 agaccaactg tctgccggaa attaccgggc gcgtctgtcc gcaggatcgg ctatgcgaag
     6181 gcgcgtgtac actccgcgat gagtatggcg cggttaccat cggcaacatt gagcgctata
     6241 tctccgatcg cgctctgagc aaaggctggc gtcccgacct gtcggacgta cagaagagcg
     6301 ataagcgcgt ggcgattatc ggcgcggggc cggcaggtct tgcctgcgct gacgtgctgg
     6361 cgcgccgtcg ggaaatcttc agcgcgatgg ggattcgttt cgaacttaac tgcgaagtag
     6421 ggaaagatat ttctctggag acgctgctgg agagttatga cgccgtcttt gtcggggtag
     6481 gaacctatcg ttccatgaag gctgatttac cgaatgaaga cgcgccgggg gtatatgatg
     6541 cgttgccatt cctcatcgcc aataccaaac aggtgatggg gcttccggcg ttgcctgacg
     6601 agccgtttat tgatactgcg ggccttaacg tggttgtgct gggcggcggt gacaccgcaa
     6661 tggactgcgt acgtacggcg ttgcgtcatg gcgctgccaa cgtcacctgc gcttatcgcc
     6721 gcgatgaggc caatatgcca gggtcgaaaa aagaggtgaa aaacgcgcgg gaagagggcg
     6781 cgaactttga atttaacgtt cagccagttg agttggtgct ggatacgcac gggcgcgcca
     6841 gcggtattcg ctttttgcgt acgcggcttg gcgaaccgga tggtcagggg cgacgccgtc
     6901 cggtacctgt accggacagc gagttcgtga tgccggcgga tgcggtcatt atggcgtttg
     6961 gttttcatcc gcatggtatg tcgtggctgg aatcgcatgg cgtgaaggtg gataactggg
     7021 gacgtattgc cgccagcgtc gagagcgagt ttcgttacca gacgtccaac ccgaaaattt
     7081 tcgctggcgg cgatgcggtg cgcggcgccg atctggtggt gacggcgatg gcagaaggcc
     7141 gacatgccgc gcaggggata ctcgactggt tagctaaata agcgtatttg taggccggtt
     7201 aaggcctgga acggttaaat gatttagtga taaaaaatct taaacttatt ggctaacctt
     7261 actccgtttg cagaaatgtt gacgctcgca gggctggacg ccctgcgata aacattttcc
     7321 cgctgggtcg atgtttaaca ggcctgataa ggtcaatctt agtattgaaa atagagtgta
     7381 aattgaagga agggacgcta tcagaatccc ttcttagagc ctatcccatt agggctattt
     7441 tacgtgccat tttggacctg ggcagtgctc gccaaaacgc gttagcgttt tgaacgccgc
     7501 ttgcggcggc ccgaaggacg agcgtagcga gtcaaacctc acgtactacg tgtacgctcc
     7561 ggtttttgcg cgctgtccgt gtccaaactg gctgcgccaa taacgtctgg tgggataggc
     7621 tcttaatttt tattttaagg aaccatatat ctggtcaaca atccagccat acgtcgccgc
     7681 aggtaataat ccactgacaa aaacattcgg gttcacttta ggatttgcta ccggcgagtg
     7741 cggcctgtta cctaaaataa caatcgccat atgattaacc ggatcgatag acgtcagcgt
     7801 tccggtccat ccggtatgtc catacgtttg cggactggct aataccccga acgttggggt
     7861 cattgaggcg ttgccgttaa cgcgccaccc cagaccaaag gtagcatctt ctggcgagcg
     7921 gcgagtaaac tgcgcaaccg ttttgttgtc gaatagcttc acgttaccgt agccgccccc
     7981 attgagcatg acttgcatta acacagccat atcatgggtg tcagaaaaca gtccggcgtg
     8041 tcctgaaacg ccgcccattg agtaccaggc tttttcgtca tgcacctggc cccatagtgt
     8101 attggtgcga atattgggga aatgaatcac gccgtcacgc gtgttgccgt gtagttccgt
     8161 tgcggcgatt tgcggcggcg tgaagccttt catcagcggg ttaaagacgg tatgttttaa
     8221 tccgagcggt ttataaatgg tggtttcgac gtagcgatct aatggcattg ccgttatcga
     8281 ttcaatgata aaaccaagaa tcatataatc cacgtcgctg tagatatgct tcgacccagg
     8341 ttgatattcc agcggtgtct ttttaatcat ctccagagta gtgcttttac tctgtgaaaa
     8401 taatttaccg gcgacgtttt tattgggata ttgtgggtcg gcaggaaagc ccgcgacgtg
     8461 atgaagaata tcaataatgc ggagtttatc tttgcctttt attttatccc caggcatatc
     8521 cttaaagccg gggatatatt ttgataccaa atcattgaca tctatttttc cttcatacac
     8581 cagtttttgc aatgcaaagt tagtggcata catttttgtg tttgaagcca ggtcatacat
     8641 cgtgttagtg gtcgcccgaa tgggatgggc taacagcgtg gaaccgtcat attttttggc
     8701 atagccccag gctttttgta gaacaatatg attatctttt atcaccagaa gattgatgct
     8761 gggatatccg gcatcaattt gattttgaat ccagccatca agtcggtgaa gtttttggct
     8821 atcaaacccc acctgatcag ggctcgcggt ggtcaatacc ggatactcaa cggcaaaagc
     8881 tgaaagggaa aacgtcagta gaaccgtcgc aacgagagta aatttcatga tgattccctc
     8941 agtctcactc cggccgtcaa atcatatcgc gagcatggac tctgcggccc ggagaagcag
     9001 aatgtggtca tggcagtgac agaaaaatat ggctgtacat ccgttcagtc ggcattaagg
     9061 attaaccctt cagcagacaa aaccgacctc acggcgtaat attaatgctc tttttacacc
     9121 ctggagccag catgtcgcaa accattacgc ttattaagga taaaattctt tctgataatt
     9181 attttactct gcgcaacatt acctatgacc tgacccgtcg taatggcgag gttatccgtc
     9241 acaagcgtga ggtttacgat cgcgggaatg gcgcaaccat tctgctttac aactcaacta
     9301 aaaaaaccgt ggttctggtt cgccagtttc gcgtggcgac atgggtcaat ggtaatcaag
     9361 acggtatgtt aattgaaacc tgcgctggcc tgcttgataa cgacgagccg gaggtctgta
     9421 tccgtaaaga ggccattgaa gagacagggt atgacgttgg tgaggtacgc aagatatttg
     9481 agctgtatat gtcgccaggc ggcgtcacgg agctgattca tttcttcatt gccgaatatc
     9541 atgatagcga gcgtgccagc atcggcggcg gcgtggagga cgaagagatt gaggtgcttg
     9601 aactaccgtt ttcccgggcg ctggaaatgg tgcgctcagg cgagattcgg gacggtaaga
     9661 ccgtgttatt gcttaactat ttacagacgt ctcatctaat ggactgaaaa aaaagaaata
     9721 tatttcttta cacaaaaaag accaatccga taaatctgat tgagaaccct gaggcgcgca
     9781 aggaagatac cgcctgagct gtgttgttct gaatctgggg ttgttccgtt catgcgctac
     9841 cgcgttattc ttttttgtct gtttggcctg ttgccggtcc agctactgtg ggctgcgcca
     9901 gcgcaacgga ctttttccga ctggcaggtc acctgcaata accaaaattt ttgcgtagcg
     9961 cgcaatactg gcgaacatca tgggctggtg atgacattaa gccgcagcgc cggggcgcgt
    10021 accgatgcgg tactgcgtat cgaccgcggc ggtttggcgc cgcccgacgc taaagaagcc
    10081 gcaattgcgc ctcgcttatt gctggatggc aaaccgcttt cgttcaacag ttcacactgg
    10141 cgcgtgtcgc cctggcatct catgaccggc gatcctgcca ccatcaccgc atttttacag
    10201 acgattcagg atgcgcaggc catcacctta aaaaacggcg ttcagacgct ttcgctggcg
    10261 ggattaaaag cggcattact gtttatcgac gcgcaacaaa aacgtgtggg cagcgaaacc
    10321 gcctggattg aaaaaggaaa cgaaccgccg ctcagcgtgc ccccggcacc ggcattaaag
    10381 gggatcgccg ttattaatcc aacgcccgta ccgctgagtg aggaagaacg cgacgatctg
    10441 ctggactacg ccgcatggcg ggtaaacggc attcgttgtt cgcttgaccc gctgcgtcgc
    10501 gagacgcagg tcagcgcgtt gacggatgat aaagcgttat tgattgttaa ctgcgaagcc
    10561 ggcgcctata acactattga tctcgcctgg gtagtttcac gcaaaaaaac gctcgtctcg
    10621 cgcgccgtac gtttgcggct gccgtttaat cgcggcgtcg aaagtaatga catggagttg
    10681 atgaacgcct tctttgacga gaaaacgcgc gagctggtga cgttggcgaa agggcggggg
    10741 ttaaccgact gtggtatcca gacgcgctgg cgctatgatg gcgatcgttt tcgtctggta
    10801 cgttatgccg aagaaccgag ctgcgatagc tggcacgggc cggatgcctg gcctacgctg
    10861 tggatcacgc gttgaatcct ggttgttatc cccttttcag aatagggata cacctattga
    10921 ggtttcattt atggtataga gattgctacg ttacggtagg attgttactt tacccgatag
    10981 cctcaccaca gcaggaaata gtatgaaaat aaataatggc cccgtattat gcccccattg
    11041 tggctgcctg agcgcttatt atgaaataga tcggctggcg gcgataagag aaaaagtgaa
    11101 taaagaaggc ggatcagcgg cgtgggattc aacattgcag gcgcataaaa aaaaggcctt
    11161 ttgcctgatg tgccataaat ccattgatga ggtcgtcatc gggcagtcag atgcgcctga
    11221 gtctacgaag taattttgca cagcctacag aacaggtctg cagactgtgc aaagtctgtg
    11281 ttgctaacgc ccgccttagc ctttgatgtt cagcacccgg cgggcttttt ccacaatatt
    11341 ttccacggta aagccaaaat acgggaacag tttgtcagcc ggggcggatt caccgtatcc
    11401 cgtcatgccg ataattgcgc cttttaggcc aacatattta taccagtagt cggctatacc
    11461 ggcctccacc gcgacgcggg cggttacgtg cgccggtagc actgattcgc gatatgcctc
    11521 gtcctgcgca tcgaaaatat ccgttgaagg caacgacacc acccgaacgt tatgcccctc
    11581 gccagtcaat ttttccgccg cctggagggt aatttccatt tccgatccgg tagcgatcag
    11641 aatgatatcc ggcttgccgc cgctatcttt cagaatataa ccgccgcggg caatcgcttt
    11701 cacctgttcc ggcgtgcgtt ccacctgcgc cagattctgc cgcgagagaa tcaacgccgt
    11761 cggcccgtgc tgacgttcaa tggccagctt ccaaccgact gccgcctcaa cctgatcgca
    11821 gggacgccag gtgctgaagt taggcgttaa gcgcaggctc gccagttgtt ccatggcctg
    11881 gtgcgtcggg ccatcttcgc ccaaaccgat ggagtcgtgg gtatagacca taatctgccg
    11941 ggctttcatt aaggccgcca tacgcgccgc gttacgcgca tattcgacaa acatcagaaa
    12001 cgtggcggta tacggtacaa agccgccgtg gtgggcgatg ccgttggcaa tggcggtcat
    12061 gccgaattcg cgcacgccat agtggatgta attacctgcc ggatcctctt tcaacgaggt
    12121 caaacctttc cagatagtca ggttgctcgg cgccagatcc gccgatccgc ccaacagttc
    12181 cggcaacagg ggaccatagg cattgagcgt attttgcgat gctttacggg tggcgatttt
    12241 ggccggatta gcctgcaagt cgttaataaa tttttgcgtg gcggattccc atgcctccgg
    12301 caatccgccg ctcatccggc gggtaaactc cgcggccagc tcaggataag ccttctcata
    12361 agcagcaaac ttttcctgcc actgctgctg cgctttctcg cctttttcac ggccatccca
    12421 cgcgcggtaa atctcttttg ggatctcaaa cgccggatga tgccatccca gcttctggcg
    12481 ggtcagcgcc acctcttctt cgcccagcgc cgcgccgtgc gactcctcct tcccggcttt
    12541 attcggcgag ccaaaaccta tcaccgtccg acagataatt agcgaaggtt tatcttttac
    12601 gctctgggct tccagaatgg cttttttcac cgcctccgga gcgtgcccgt caatgtcatg
    12661 cacgacatgc cagtggtagg cttcaaaacg tttggctgta tcgtcggtaa accagccttc
    12721 ggtttcgcca tcaatggaga tgccgttgtg atcgtaaaag ccgatcagtt tgcccagtcc
    12781 cagcgtacca gccagcgaac acacctcatg cgagatcccc tccatcagac agccgtcgcc
    12841 cataaagaca taggtgtagt ggtcgacaat ctcatggtcc ggccggttga actgtgcgcc
    12901 taacgtacgc tcggcaatcg ccagcccgac ggcattcgcc agcccctggc ccagcggccc
    12961 ggtggtggtt tcaacgccag gcgtatagcc aatctccggg tgaccaggcg ttttagagtg
    13021 cagttgacgg aagtttttta gctcctccag cggcaggtca tacccggtta aatgcagcag
    13081 actatagagc agcatggagg cgtgactgtt ggaaaggata aaacgatcac ggtcatacca
    13141 ggtcggatcg gtggggttat gtttaagaaa atcgttccat agcacttcag cgatatccgc
    13201 catccccatc ggcgcgccgg ggtgcccgga attggctttt tgaacggcat ccatgctcag
    13261 cgcacgaatc gcattggcaa ggtctttacg ggacataaat cactccatgc aaggtttata
    13321 gtttggcggc aagcaggtct tccagtttgc gctggtcaac ggcgaaaagg cggatacctt
    13381 ccgacagctt ctctacggcc atcgcgtcct gattatgttc ccagcggaac tccgcttccg
    13441 tcattggcgt aggacggtgg aacatctgcg aggaaggcac cagtttacgg atcaccggtt
    13501 cttctttttc tttcagctct ttaagcaggt taggggagat agtcagtcga tcgcagccgg
    13561 ttagcgcgag gatttgctca gtacggcgga aacttgcacc catcacgatg gtttcatagc
    13621 gatgctgttt aaagtaatcg tagatattgc gtaccgattt cacgccggga tcttcctcca
    13681 cgacatacgg ctccagcgga ctacgcgcct gataccagtc gtaaattcgg cccacgaacg
    13741 gagagattaa atagacgccc gcttcggcgc aggcgcgcgc ctgggcaaaa gagaacaaca
    13801 acgtcaggtt gcaattaatg ccttcttttt cgagctgttc ggcggcgcga ataccttccc
    13861 aggtcgcggc gagcttgatc agaatgcgtg atttatcaac atcctgctgc tggtagagat
    13921 ccaccagatg gcgtgctttc tcgatacttt tttctttatc gaacgataac cgcgcgtcga
    13981 cttcagtgga gacgcgaccg ggaatacttt tcagtatttc cgcgccaaaa ttaaccgcca
    14041 gtttatcgct ggctgccgca acctgctgtt cctgcgtacc gccgtgtttt tttccccagg
    14101 caatcgcatc ctcaatcaaa tgaccatact gctcaagccc ggcggctttt aacagtaaag
    14161 agggatttgt cgtggcatcc tgcggctggt agtggcggat ggactcgatg tcgccgctgt
    14221 cggcgacgac ggtagtgaat tgtttgatgc cgtctagctg gttcatagga aatactcctt
    14281 gaaaagtaaa gtgttagatg agtgtgttga ttcacacttc tgaaagattg atacactaca
    14341 taaccaaaaa gcatagcaga caggcatggt attgctggta taagcaggta acatggctgt
    14401 tataagttga taacaaactc ttgcgccgcg tcgtgatagt ttgcagacct tcaaagtttg
    14461 tgttgcgcag tacggtgata atgtgcggcg caccaggccg cgtcactttt tgaacgatac
    14521 gtgaaaggaa caacaaaatg gatgagcagt taaaacaaag cgcccttgat ttccacgaat
    14581 ttccggtacc cggtaaaatt caggtttctc cgactaagcc ccttgccacc caacgcgatc
    14641 tggcgttggc ttactcgcca ggcgtggcgg cgccctgcct ggaaatcgaa aaagatccgc
    14701 tggcagccta caaatacacc gcgcgcggca accttgtcgc ggtcatttcc aacggtacag
    14761 cggtgctggg gttaggcaac atcggcgcgc tggccggcaa gccggtcatg gaaggcaaag
    14821 gcgttctgtt taaaaaattc gccggcatcg atgtgtttga cattgaagtc gatgagcttg
    14881 atccggacaa atttatcaat gtggtcgcag cgctggagcc gacctttggc ggcattaacc
    14941 tcgaagacat taaagcgccg gaatgtttct atattgagca gaaactgcgc gagcgcatga
    15001 acatcccggt tttccatgac gatcagcacg gaacggcgat catcagtacg gccgccattc
    15061 ttaatggcct gcgagtcgta gagaaaaata tttccgacgt gcggatggtc gtctccggcg
    15121 caggggcggc ggcaatcgct tgtatgaacc tgctggtcgc gttggggatg cagaagcaca
    15181 acatcgtggt gtgcgactct aagggcgtta tttacaaagg ccgtgagccg aatatggcgg
    15241 agaccaaagc ggcctatgcg gtagacgaca gcggcaagcg cacgctggat gaggtcattg
    15301 acggcgcgga tattttcctc ggctgttcag gcccgaaagt gctgactcag gagatggtga
    15361 agaaaatggc ccgcgcgcca atgattctgg cgctggctaa cccggaaccg gaaattctgc
    15421 cgccgctggc gaaagaagtg cgtccggacg ccatcatctg taccggtcgt tccgactatc
    15481 cgaaccaggt gaacaacgta ttgtgcttcc cgtttatctt ccgcggcgca ctggacgtcg
    15541 gcgcgacggc gatcaacgaa gagatgaaac tggcggcggt ccgtgcgatt gccgagctgg
    15601 cgcacgccga acagagcgaa gtggtggcct cggcctatgg cgatcaggac ctgagctttg
    15661 ggccggaata cattattccg aaaccgtttg acccgcgtct gattgtcaaa atcgctccgg
    15721 cggtcgcgaa agcggcaatg gattccggcg tggcgacgcg cccgattgct gactttgatg
    15781 cctatatcga taaactgacc gagtttgtct acaaaactaa cctgttcatg aagccgatct
    15841 tctcgcaggc acgcaaagat ccgaagcgcg tagtgctgcc ggaaggggaa gaggcgcgcg
    15901 tgctgcacgc aacccaggag ttgataaccc tggggctggc gaagcccatc ctgatcgggc
    15961 gtccgagcgt gatcgaaatg cgtatccaga aactggggtt acagatcaaa gcgggcgttg
    16021 atttcgagat cgtgaataat gaatccgatc cgcgcttcaa agagtactgg agcgagtatt
    16081 accagatcat gaagcgtcgc ggggtaactc aggaacaggc gcagcgtgcg atgatcggca
    16141 accatacggc cattggcgcg atcatggtgc agcgtggaga agcggatgcg atgatctgcg
    16201 gcaccatcgg cgactaccat gagcatttca gcgtcgtgaa agccgtcttt ggctaccgtg
    16261 acggcgtgca tacggcaggg gcgatgaacg ccttactgct gccaagcggc aacactttta
    16321 tcgccgatac ttatgttaac gaagatccca cgccggaaca gttggcggag atcgccgtaa
    16381 tggcggcgga aaccgttcgc cgctttggta ttgagccgaa agtcgcgctg ttgtcgcact
    16441 ctaactttgg ttcctcaaat tcgctgtccg ccagcaaaat gcgcgaaacc cttgagcggg
    16501 tacgcgaacg agcgcccgat ctgatgattg acggtgagat gcacggtgat gcggcgttgg
    16561 tggaaagtat tcgtaatgac cggatgccgg atagtccgct gaagggagcc gccaatattc
    16621 tggtgatgcc gaatatggaa gccgcccgca ttagttacaa cttactccgc gtctccagtt
    16681 ccgaaggcgt cacggtcggc ccggtcctga tgggcgtgtc taaaccggta catgtattaa
    16741 cgccgatcgc ctctgtacgc cgtatcgtga atatggtggc gttagcggta gttgaagcgc
    16801 aaaccacgcc gctttaataa cgcattactc tctcttctgg cgcaggttct cctg
//
LOCUS       DAJVKX010000094        16773 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000094 DAJVKX010000000
VERSION     DAJVKX010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16773
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.094"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..530
                     /gene="siiD"
                     /locus_tag="OPY25_003147"
     CDS             <1..530
                     /gene="siiD"
                     /locus_tag="OPY25_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiD"
                     /protein_id="HCS0928699.1"
                     /translation="VNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADL
                     LFEIKPKVRTMLADVKILPKYRDQIYVDEAVKLDVQSIIQPKIKSYNATIDNISPDSY
                     EENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEYLLSPLMKGVD
                     KAFSEPVNTKRLDTP"
     gene            547..16623
                     /locus_tag="OPY25_003148"
                     /pseudo
     CDS             547..16623
                     /locus_tag="OPY25_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463126.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain repeat protein"
     gene            16663..>16773
                     /locus_tag="OPY25_003149"
     CDS             16663..>16773
                     /locus_tag="OPY25_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-1 secretion protein"
                     /protein_id="HCS0928700.1"
                     /translation="MDKKLEPYYLSAETALSIVSKKFNIKIDIKEDDINLR"
BASE COUNT         4727 a         3624 c         4409 g         4013 t
ORIGIN      
        1 ttgttaactc tacattaaaa gtaatagaga agcagataaa tgaggaggat atctattcac
       61 cggttgacgg tgtaatttat aaaatcaata aaagtgccac tactcatggt ggtgtgattc
      121 aggcggcgga cttacttttt gaaataaaac caaaagtaag gactatgctg gccgatgtga
      181 aaatactacc aaaataccgt gaccaaatat atgtagatga agccgttaag ctagatgtcc
      241 agtcaattat tcaaccaaag ataaaatcgt ataatgcgac tatcgataat attagccctg
      301 actcttatga ggaaaatacc ggaggaacaa ttcagcgtta ttataaagta attattgcat
      361 tcgatgttaa tgaagatgat ttacggtggt taaaaccagg tatgactgtt gacgccagtg
      421 taattaccgg aaaacacagc attatggaat acctgttatc tcctttgatg aaaggcgtgg
      481 acaaagcctt ttcagaacca gttaatacta aacgattaga tacaccttga gagtgaatat
      541 aatattatgg gaaataaaag catacaaaag ttttttgccg atcaaaattc tgtaattgat
      601 ttatcttctt tgggtaatgc caaaggcgca aaagtttctc tttccgggcc agacatgaac
      661 attaccacgc cgcatgggtc agtgatcatt gtcaatggcg ctctttattc aagtatcaaa
      721 ggcaataacc tcgctgttaa atttaaagat aagactatta ccggcgctaa aattctgggc
      781 agcgtagatt taaaagatat tcaactggag agaattgaca gctcattagt tgattctgct
      841 caggtagaaa agaaaggtaa tggcaaacga cgaaataaga aggaagaaga ggaattaaaa
      901 aagcagcttg acgaggctga aaacgcaaag aaagaagctg ataaggcgaa ggaagaagca
      961 gagaaagcta aggaggcagc agaaaaaacg ctcaatgaag cgtttgaagt acagaactcg
     1021 tcaaagcaaa ttgaagaaat gctgcagaac tttttggctg acaatgtagc aaaagacaat
     1081 ctggctcagc aaagcgatgc ttcccagcaa aatacacagg ctaaagcaac gcaggcttct
     1141 aaacagaacg atgctgaaaa agttcttcct caacctatta ataaaaatac cagtactggc
     1201 aaaagtaata gcagtaaaaa tgaggaaaat aagctcgatg ccgagtctgt taaagagccg
     1261 cttaaagtca cattagcgct tgcggccgag agtaacagcg gtagcaaaga tgatagtata
     1321 actaatttta ccaaacctca gtttgtaggt agcactgctc ccaatgccac ggttattatt
     1381 aaaattaatg gtattgctgt cggtcaggct gtagcggata gtttgggtaa cttcaccttc
     1441 acagcgcctg aaacattgac tgatggaaca tacaatctgg aggcagaggc caagactgct
     1501 gatggaagcg gtagcgccaa acttgtcatt actatcgatt ccgttaccga taagccaaca
     1561 tttgaacttt cgcctgaaag tagtgtgtcc ggtcataagg gcttaacgcc gaccttgacg
     1621 ccttcaattg ttggtacggc ggaagagaat gctaaggttg acatttatgt agataataaa
     1681 ctggttgcca gcgttgatgt cgataaagat ggaaactgga gttatgaatt taaagataat
     1741 gaattatctg agggcgaaaa tagtataaaa gtcgttgccg tggataaagc aggtaataaa
     1801 aacgaaacga cggatagtat cataaccgac accattcctc cggaaaagcc gacgattgag
     1861 ctggatgata gtagtgattc cggcattaaa aatgacaaca ttacaaatag cactctgcca
     1921 acatttattg gtgtggcgga acctggttct acagtctcta tttatcttgg gcttaaacat
     1981 cttggtgagg tcattgttgc taaagatggg acatggagct atacgcttac tacgccgctc
     2041 aaggatggcg aatacaatat aacagcaacc gctactgata ttgccgggca tacctctgcg
     2101 acggcaaatc tgccttttac tattgatacc cgtatcagct atttcagcgc tgagattgaa
     2161 acgactgatg atagcggtat tgttggagat aacgttacta acaatactcg cccaaccttt
     2221 acaggtaaaa ctgagccaaa tgctattatc agtgtcataa atagtgagac tggcgaagag
     2281 gttattttta aagcgaatga caagggcgaa tggacgttca atttcacttc agactcagtg
     2341 gaaggggtta acaatcttac gttcactgtt gaagatgtcg ctggcaacaa aaaggatttt
     2401 tcctttagtt acgttatcga tactgttgcc cctgtacctc cgacggtttc tttggaggat
     2461 tttgttgttt taccgaatgg tataatttta tcagggaatg atttaccggc tttagtcggt
     2521 acggcagagc caaagtctac catcttattg atgcgagatg gtaaattata tgacagcatt
     2581 gaggttgact caaacgggac ctggaattat cagtttagta ataaatttct tcagggcgcc
     2641 tatgatattg aaatcatttc tcaggatgcc gccggtaata aatcctctac tgttaaatat
     2701 tcttttacta ttcaaactga agttgtacct ccaaaagcgg aactcgatgc cagtgatgat
     2761 tccggtgcaa aaggcgactg gattaccaat aaacataatg ctctgacatt actgggaaca
     2821 gcggataggt ttgctaccat aaatatcctt atcgatggta aaacgatagg cgtgacgact
     2881 gcggatgcag acggtaactg gaattttgat atttcccgaa atctgtctga caatgtttat
     2941 aagattacgg ttgaatctat cgatccttta ggaagaacgt catctgtaga ttatcagctt
     3001 accattgata gctttacgcc gatccctact gttatgttgc atgatagcgc tggctctggc
     3061 gttaaaggcg atatgattac taaaattaat acgccgttgt ttaccgggat ggctgaagct
     3121 aatgctaagg tttccatcta tgttgacggt gtgttaagtg gcgaggctat tgctggcgat
     3181 gatggtgtat ggaattttca atttaccaca gcgttgtccg atggctcgca tgacgtaacg
     3241 gtaaaggtag aagatattgc cggtaatact gcctcctcat cagcgtataa tttccaaatc
     3301 gtaacgcaaa cgcaaaaacc aacaatagag ttggtcaacg atacgggggt tgataataca
     3361 gaccatatta ttaatgaaaa gaatcctgca ctgacaggga ccgctgcacc ctattcaacg
     3421 gttaaactct atgttgatgg cgcactaatc gctgaggtca gaacaaataa agatagcaga
     3481 tgggagtata ccctgaaagc cgatcaaggt ttggttgatg gcgatcatag aataaccgct
     3541 tcagttgaag atatcgctgg caacattgcg cattcggatc ctttcttaat tagcgttgat
     3601 actgctattt caataccgat agtttcattg agcccggatt cagattcggg aatcgcagat
     3661 gataatttaa cgaatatcgt taaccctacc ttgcacctaa aagatattga tccggacatt
     3721 atcagcgttc aggtatggga tgccgcgtct gatacgcaga tcggtgttgc cacgcaacaa
     3781 cctgatggtt catggaccta tacctttact tcagatttaa cggaaggctt gcatcaggtt
     3841 tatgtcaagg ttgaggacat tgcgggtaat aaagcgaaca gcgcggtatt cgattttact
     3901 atcgatacca cagtatcaac gccggtgatt tccctgcttt ctaaggatga tacgggggtg
     3961 acaggcgata acctgaccaa tatcaataag ccaggttttg ctatttccgg tgttgatgcc
     4021 gatgcgcatc gggtcgtcgt acaggtgatg cacaatggcg tgagcgaaga gatcgaactt
     4081 tcccacctca atggtagttg gttatttaca ccagggaata cgtgggcgga tggcagctac
     4141 acgttaacgg tgaaagtaga agataaggca ggaaatacca gctattcagc gccgctgacg
     4201 gtcgttatcg atacccaaat cgccattgat ggggtggaac tggtcaacga tagcggcgtg
     4261 aaaggcgaca atatgaccaa cgacgaccgt ccccactttc gtgtgacggt acctacggat
     4321 gtcaatgaag tccgtctgag cattgacggt ggtaattcgt gggttcaggc aaccccgggc
     4381 gtggcaggaa gctgggagta tatctggccg acagacctgg cagatggtca atacacgcta
     4441 acggtggaag cgactgataa agcaggcaat acagtgacga agaccatcga tttcgcggtg
     4501 gataccacgc tgtcagtgcc ggtcatcgta ctgaatagcg cggacgatac cggtgtccag
     4561 ggcgataaca tgacgaatcg cacccagccg acatttgccc tgcagcatat tgatgatgat
     4621 gccgttcgcg ttacggtcag cgtggagcat ggcggcgtca ccaccacatt tgacgccacg
     4681 aaaggcacag gcggatggac ctttacgccg ccgacatcat gggcggatgg tgattatacc
     4741 ctgagtgtgt cagtcgaaga taaagcgggg aacaccagcc attctgcatc gctgacggtg
     4801 acggtggaca cgcaaatcgc cattaataac attgaactgg tcaatgacag cggtattccc
     4861 aacgataatc tgactaataa tgtgcgtcca cacttccagg tgacggtacc gacggatgtc
     4921 aacgtggtgc gcctgagcat tgacggcggc aagacgtggt tcaacgcgac ccagagcgcg
     4981 acgccgggcg tctgggatta tatctggccg gatgatgtgg ccgacggagg ctataccctg
     5041 acggtagaag cgaccgatga ggcgggaaat aaggcaacac agacgctcga tttcaccatc
     5101 gataccactc tgtctgtgcc gaccctctcg ctggacagcg cagatgacag cggcatcgcg
     5161 ggcgataata tcaccagtgt taaaacgccg ggctttaccc tcaacaatat tgataccgat
     5221 gtcagccggg tgatagtgga ggtaatgcac aatggcatta aacaggaggt accactggtt
     5281 cagaccggcg gacagtggcg ctttgcgccg accagcgact gggcggacgg cggctatatc
     5341 ctgacggtga aggtagaaga cagggccgga aatgtgaagc agtccgcgcc gttgacggtg
     5401 acagtggaca cgcatatcgc cattgaccgt attgaactgg ttaacgacag cagtatcccc
     5461 gacgataatc tgaccaatga agcgcgcccg cactttcagg tgacagtacc ggcggatgtt
     5521 aacggtgtaa gactgagcat tgatggcggc aaaacgtggt ttgacgccac gcagagcgcg
     5581 acgtcgggcg tctgggatta tacctggctg acgaatgtgg ctaacggccc tcacaccctg
     5641 atggtggaag cgaccgacaa ggcgggaaac aaaacgacgc agaaactgga cttcatcatc
     5701 gataccctgc tgtcagaacc gactattacc ctggacagtg cggatgacag cgccgctggc
     5761 gataacatca ccaacgttaa gatgccaggc tttaccctcg gtaatatcga cgccgacgtg
     5821 accaaagtgg tggtgacggt ggcgcatgat ggtaagaacc aacagataga gttgattaag
     5881 aacggcggtg tgtggcgctt tacgccgggc gcagcctgga ccgatggcga ctatacgctg
     5941 acggtaaagg tagaagataa ggcgggtaat acaaattatt ctgcgccgct gacggtgact
     6001 atcgatacgc aaacgtctat tgatcgcatt gggcttctta atgacacggg tattgtcggg
     6061 gataacctga ccaatgaagc acgtccacag tttcatatta cggtaccgac ggacgtgaac
     6121 tctgtgcaac tgagtcttga tggcggcatc aactgggtta acgcaacgct gacgtctgac
     6181 ggcgtttggg agtatatatg gccgacagat ctggtcgaaa atacgtatac cctgacagtg
     6241 aaagcaaccg atgttgcagg caacacggcg acggaaacgc tcaattttat cattgatacc
     6301 acattgtcga caccgaccat cacgctggat agcgcagatg atagcggcac cgccaacgat
     6361 aataagacta acgttaaaac gccgggtttt attatcggcg gtattgattc tgacgtgact
     6421 caggtcgtcg tgcaggtgat gcgcgatggt cacagcgagg aggtggagct gacgcagact
     6481 aacgggcagt ggcgttttgt acccggcagc gcgtggactg atggcgacta tacgctgacg
     6541 gtaacggtga aagatgaggc gggtaatatt cgccactcag cgccgttgac ggtcaccatc
     6601 gatacgcaaa tcaccattga ccatattgaa ctggtcaatg acagcggtat tcccgacgat
     6661 aatctgacta ataatgtgcg tccgcacttc caggtgacgg taccgacgga tgtcaacgtg
     6721 gtgcgcctga gcattgacgg cggcaagacg tggttcaacg cgacccagag cgcgacgccg
     6781 ggcgtctggg attatacctg gctggctgat gtgggagagg gtaagcatac cctgacagtg
     6841 gaggcgaccg acaaggcggg aaacaaaacg acgcagcaac tggacttcat catcgatacc
     6901 ctactgtcag aaccgactat cgtgctggac agcacggacg acagcggaac aaaaggcgat
     6961 aacctgacca atcgcaccca gccgacattt gccctgcagc atattgatga tgatgccgtt
     7021 cgcgttacgg tcagcgtaga gcatggcggc gtcaccacca catttgacgc cacgaaagac
     7081 gcaggcggat ggacctttac gccgacaggg gcgtgggcgg atggtgatta taccctgagt
     7141 gtgtcagtcg aagataaagc ggggaacacc agccattctg catcgctgac ggtgacggtg
     7201 gacacgcaaa tcgccattaa taacattgaa ctggtcaatg acagcggtat tcccaacgat
     7261 aatctgacta ataatgtgcg tccacacttc caggtgacgg taccgacgga tgtcaacgtg
     7321 gtgcgcctga gcattgacgg cggcaagacg tggttcaacg cgacccagag cgcgacgccg
     7381 ggtgtctggg attatacctg gctggctgat gtgggagagg ggaagcatac cctgacagtg
     7441 gaggcgaccg acaaggcggg aaacaaaacg acgcagcaac tggacttcat catcgatacc
     7501 ctactgtcag aaccgactat cgtgctggac aacacggacg acagcggaac aaaaggcgat
     7561 aacctgacca acgtaaataa gccgacgttt ttactgggca atattgacgc agacgcgcgg
     7621 tatgtcacgg ttgaggtgca gcatggcggc acgaaagaag tgctgacggc caccaaaggc
     7681 gcgaccggca tctggagcgt gacaccgacc ggcacatggg cagatggcga ctatacgctg
     7741 acggtgaggg tggaggatga tgcggggaac gtaaaatact cagcgccgct gacggtcacg
     7801 gttgataccc aaatcaccat cgatgttatt gaactggtta atgataacgg tattcccggc
     7861 gacaacctga ccaatgacgt tcgtccacac ttccgcgtca cggtgccagg ggatgtcaac
     7921 gaggtacgtc tgagtatcga cggcggtaat acgtgggttc gtgcaacaca gggcacggca
     7981 gggatctggg attacacctg gccgaaagat gtgaccgacg ggctacatac cctgacggta
     8041 gaagcgaccg ataaggcggg aaataagacg acgcagacgc tcgattttac cattgatacc
     8101 cggctgtcaa cgcctaccat cgctatggac agcagggacg atacaggtgc cattggcgat
     8161 catattacga gcgtcaaaag accgggcttt accattggca atattgacgc cgatgcgcac
     8221 tcggtcattt tgcggatcac acagggcggc aatagccagg aagtgacact aacccaggtt
     8281 ggaggacagt ggcgctttac gccagatgct gactgggcgg acggtagcta tacgctgacg
     8341 gtagaggtaa cggataacgc aggaaacgtt cgtcagtcca cgccgctggt ggtgacggtg
     8401 gacacgcaaa ccagcattac tgatattaca ttggtcaatg atcatggcgt gcctgatgac
     8461 aatctaacta atagcacccg tccgcagttt gagatcacgg tgccggcgga tgtgaattct
     8521 gtgcaactga gcattgatgg gggcgcaaac tgggtgagcg cgacgcaggg tatcgaaggc
     8581 gtctggggct atacctggcc aacggatatg ggcgatggaa aacacaccct aaccgtcatg
     8641 gtcaccgaca gagcgggcaa tacggcgacg caaacgcttg aatttttcat cgacacccgg
     8701 ttgtcgacgc cgaccattgc gctggatagc acggatgata ccggtacgcc tggcgatgat
     8761 atgaccaatc gcacccggcc gacttttatt ctgcagaata tcgattcgga tgttatcaac
     8821 gttacagtca gcgtcacgca taatggaacg acaacctcgt ttaccgcgac acagggggct
     8881 ggaggatgga gctttacacc gccagcgccg tggggcgacg gtgattatac gctgacggtg
     8941 acagtggagg atcgggcggg aaatacgcgt ccgtctacgc cgctgacggt gacagtggat
     9001 acgcaaatag ccattgatca tattgaatta gtcaacgata gcggcgtccc tggcgataat
     9061 gtgacaaaac atgtgcgtcc gcagttccag atctcggtac cggatgatgt ggaaaaggtt
     9121 cttctgagta ttgacggcgg cacgacctgg gttactgcaa tcaagagttc gacggttggc
     9181 atttgggatt acacctggcc gacggatatg ccagagggac agcataccct gatcgtggaa
     9241 gtgactgacg gtgcgggtaa taagatgacg gggacgctcg atttcactat cgacatcacg
     9301 ttgttgacgc caaccattga gctagcgccc gatcaggata ccggacagaa taagaacgat
     9361 aatctgacca gcgtcactca gccggtattt gtgttgggga gtatcgataa agatgttcga
     9421 cacgtggaat tgagtattga gcataacggc acgtttaaaa cggtggtact caccgaatca
     9481 gccgacggct ggcgctatcg accggattct gctttggcgg acggtagcta cacattcacc
     9541 gtgacggtaa cagatgtggc cggtaatcag caaacatccg cgcctttaaa ggtgacgata
     9601 gacggtacgt tgactacgcc ggtgattgag ctggcggccg gcgaagatag cggtactgtt
     9661 ggcgatcgcc tcaccaatca cgatcggcct gtgttcgaca tacgccagat tgattctgac
     9721 gttacgcgcg tgatggtcaa agtaacttac aacggtaaaa cgcacgagga agcggcggta
     9781 ttcaccaatg gttaatggcg ctttacgcct tctgcgagct gggctgatgg ctcatatcag
     9841 ttagccgttg tggtggaaga tctggcgggg aatgtaaaag aatctgcgcc gttagaggta
     9901 cgtattgata ccacgacaac cattaacaat atcgtattgc ttaatgatac tggcgtgcag
     9961 aatgatcaat taacgaatgt tgccaaaccg tcattcagaa ttgacgttcc cggtgatgtc
    10021 gtccaggtac gcgtaaccct ggatggtggc gctaactgga atgtgatacg caaaaatgcc
    10081 gacggacagt ggatttttga cagcccgaat actctggttg acggcacata tacccttcgc
    10141 gtagaggcca cggatgaggc aggtaatatt gcaaataaag atttagtatt taatatcgat
    10201 actaatatac aggttccgac tattgcttta gacgcaggac aagataccgg agcgaataca
    10261 gccgataata ttactaatat ttcacgaccc acctttacga ttggtaatgt tgaccccgat
    10321 gttatcaaag tcgtggtgac gattgatggt catgattata acgcgactaa ggttggggct
    10381 ggttggcaat ttacaccagg caatgccatt ccggatggtt cttataatat taccgttacg
    10441 gttgaagata aggccggaaa taccgcgaca tcgaaaccat tacctgttgt gatagatacg
    10501 acggctgaaa ttgaaagcgt cacgttggtt acagatagcg gtgatagcga tgtagataac
    10561 attaccaaag tcgacaagcc gcagtttagt attgttaccg ctgatgatat tacccatgtg
    10621 cgcgttaaaa tcgataacgc cgctaattgg attgaactca caaaaggagg ggatggtcgc
    10681 tggatattta atgtcggttc ggcattacct gatgggcaac acactctctt ggttgatgtg
    10741 actgatatcg ccggcaacgt tgcgcaagaa acgctgcagt ttacgattga tacgactctg
    10801 cgagagccga caattgtact cgatcccacc catgatactg gtgatgatac taatgataat
    10861 cttaccagga ttaacaaacc ggtgtttatt atcggtaatg tcgataatga tgtatcacac
    10921 attgtggttc atcttgatgg tcgggattac accattgaaa acaaaggggg gaatttaacc
    10981 tttacgccgg atcaaccgct gtctgacggt cagcatacga tctctgttac cgtaacggat
    11041 attgctggta ataccaaaac atcggccgaa ctgcagattg aaatcgacac gcaggttcag
    11101 attgacagtg ttacgttaac aacagatagc ggcgtcaacg atcacgataa tgtcaccaat
    11161 gctacccgtc cctcttttga aattgcaacg cctgatgatg tgacatcggt gctggtttct
    11221 ttcgatggcg taaactggac gcccatcagt aaaaatgcgg ccgggcagtg gcaatttact
    11281 gcaggtagcg cattgtctga tggtcattat actctccatg tccaggcgac ggatcgggca
    11341 gggaatacgg caaattccac gctgggcttt accgtggata cgcagattga cggcctgagc
    11401 gtcgtgatgc tggacgacgc cggaaaggat tctacggatg gtattacgaa tattacctct
    11461 ccacgttttg aaatttcagc cagagaacag ttgcagagcg tgacggtaat tttaaacggg
    11521 aaatccagca ccctgactca gggggcaggt aataaatggc tgtttacccc tgatacaccg
    11581 ttagtggatg gaacttacaa aatagaaata gtggctgaag atatcgcagg taataaaatt
    11641 agcaaagagg tatcattcac aatagacact attgtttctg atcccagtat tgatttgctg
    11701 gatgcggatg atactggcga aagcgctgtt gataatatta cgagtgtcac tacaccacgt
    11761 ttcgttattg gcaatgtacc cgccgatatt gatactgttg taatcagaat taacggcgtt
    11821 tcttatccgg ttacggcaaa tggcaataac ctctgggaat ttcaggttcc cgttgcgtta
    11881 aacgatggcg tatatgaagc cgttgttgtc ttcagagata ttgccggaaa tacttctgaa
    11941 actaagctgc cctttaccat tgataccacg acaagcgtca gtgtcagaat ggagccagcg
    12001 tctgataccg gcagctccaa tagcgataac cttacgaata agcaaaatcc caaattcgaa
    12061 ggtactgcag agcccaatgc gaaactggtg attaccattg ttgacgataa gtcaggtcgg
    12121 gaggttttaa aacacacgat tacggttggc gccgatggca actggagtgt gacgccgaat
    12181 atactgccgg atggcatgta taccatcaac gtcgtcgcaa cagatgtcgc gggaaatact
    12241 gcgcaaacgc aggaaagatt cactatcgat acggttacga tcgatcccac cattcgcctt
    12301 tcggatccat ctattgatga tcagtatgag gcaaccagcc tgcgtcctga gttcaaaggg
    12361 ctcgccgaag cgttctcgac gattatgatt cagtgggatg ggaaagtggt cggctcggca
    12421 aacgccaatg cgaatggtga atggagttgg acgccgccat cagtattagc gccaggctcc
    12481 tatgttgtga gcattgttgc caaagataaa gcgggtaatg aatcgtcgca ggtcgacttt
    12541 cctgtagtaa tacctgttat tgatgtcacg cctccaacca taaagctcag cgaggagagc
    12601 gatagtggtg ccttaggaga ctttacgacg aataataaaa cgccgaccct gattgggagc
    12661 acgttaccta atacaattgt gagtatttat gtggatggcg tgaaggtcgg cgaggcgaca
    12721 gcggatacag cgggccgata tactttccag ttatcggaaa tgaaagatgg ccattatgtc
    12781 gtccaggtgg gtatcgtcaa ccctcgcgat aatagcgaac tgcgttccac cgccgttgat
    12841 gtcactatcg ataccgaggt tgctgaactg gtatggaata tatctggaat gcatgagggc
    12901 ggatatatca acacggtgac gccggagatt ggcggcacca gtgagccaaa cagcaaaatc
    12961 actatctttg tgaatggcgt tgaaaaagcg attgcttata cgacaggcgc aggacactgg
    13021 ggcgtagtat tacccgcttt gggtaatgac ggtaattatg aattaacgtt taaagttgaa
    13081 gacgttgccg gcaatatcag agagtttggt ccgcagaatg tgatactgga tacggtaatt
    13141 tcgccgttaa ccgtggtatt acgcgaagct gatgacagtg gcaaagttgg cgactggatc
    13201 accaataaat ctcatgtcac catcgatggt actgccgaag ccggaagtac tttgaccatc
    13261 aggaatccgc agggagtggt tattgctacc ctggtggtag gcaatgatgg tcgatggagc
    13321 gcagaattag atctgcgtga aggtagtaat gcctttgtcg tggtatcgga agataaagcg
    13381 ggcaacggcc aacaaaaaga tattctgata gaacatgata cgcagattga aatcagcgat
    13441 atttcattaa gtcgggatac taatagcggt gataaatatg atctgattac caataataag
    13501 tctccggtac tggttgccat gaccgatccc ggcgcgacgg tacaggttta tattaatggt
    13561 gtgttacaag gcacagtaga ggcgagttcg tcaggtaata ttagctatac catgccggca
    13621 aatagcgccg acggcgagta tcaggtgcaa tttgttgcta cggatactgc tggtaaccgg
    13681 gttgaatctg cgattacgac cgtgacaatc gattctcaaa ttgctgtctt tgatattgat
    13741 gaagattcat taccggccct ctctaataac cgggcgttgt cagtctcagg cgtcggggag
    13801 gctggttctc aggtcagcat ctttgtcgat ggtaaattag tcaacgttgt tatggttgag
    13861 gctgatggct catggcgcgc gccgatactg ctgcaagatg atggtacgtt taatattcat
    13921 ttcagcatta ctgacgttgc tggcaacact caagtaagca agaattacag tgtggatgtc
    13981 gattcatcaa ccgacttccc aacgctcaac cttgaagatg cgagcaactc tggttcactt
    14041 gacgatctga ttactaatca caacaagcct gtgttagttg gcaccgcaga agcgggagcc
    14101 acaatccata tttatgtgga tgaaaagatc gtggcaaatg tgcttgtgct tgaagatgga
    14161 acctggtcct atcagtttga taatgcgtta aaagatggtg aatattctat ccgtgtggtt
    14221 gccgaagacc cggcaggtaa tacggcagaa tcgcctcgct tactcgtcac gatagatacc
    14281 agtacgttta tcgataatcc tgctatggtg gcaggttctg ataacggtat tttcagtaat
    14341 gatagtataa cgagtcagac ccggcctacg tttagtattt ttggagaaat gaaccagagt
    14401 gttcagattt tcattgatgg ggtgttagtc gatacgatca cggtgacgga cagaaatcaa
    14461 gtttatcgac ctgagtcacc gttgggcgat ggttcccata gcatttatta tgttatcacc
    14521 gataaagcag gcaacacggc tacctcgaaa acgctaaact ttactatcga tacctttaat
    14581 acgacgcctg tcgccattga ttctatcggt ggacaaacgt tagcagagat gaccggtagt
    14641 gatggcaaaa tatatataac ggacacgacg cgtaacttat tgtttagtgg cagtgccgag
    14701 cccaatagca aaatagaaat cattattaat ggcttaaatg tgggggaagt ttgggttaat
    14761 gaaaaaggcc actggcagat gccggtgaac ccgctttatt tcacagaagg ccaactggat
    14821 atcactgtta aatctacgga ccgtgctggt aacgtaaatc aggaaaagta ttccatttgg
    14881 gtcgatacgc atatccaggt atttaccagc gagcttgatg acaataaatc atcatcgaaa
    14941 acggactggt ggagtaatag ctccactatt accatgagag gtatggggga aattggcgct
    15001 acggtatcat taatcgtggc aggggtcacg ctggcaaccg ctgtcgttgc ggctaatggg
    15061 cagtgggaat tatcgaccga tcagcttccg gaagggaaat acgatatcac tttgagtatt
    15121 gaggataacg caggcaaccg taaggaagag gtacatgaaa tatttattga tcgaacgccg
    15181 ccaaacgctc cggtcgtaac ttattcagac attgtcaacg atctaattat tatgcaggga
    15241 acggcggaag ccaaatctca gctaataata accgatagta atgggaatac ttatacgtta
    15301 accgttcctg ataatggtaa atggagtatg gcgatcccgt atccatcgga agggaagttt
    15361 accattacga gtgtggatgc gattggtaac cggagtgatg atgtccctct cgatatcatg
    15421 aaagaggttc ccgttatttc attatctcca gactcagaca gtggtacggt gggcgataat
    15481 attacgcgcg ataagcaacc tacctttatt atcgggaatc tggaaagcga tgttgtggtc
    15541 gttcaggtcg atatcaatgg gacagtatat aatgctgaaa aaaatgccga tggcgtttgg
    15601 ttctttacgc caggtacacc gttagctgat ggttcctata cgatatcggt aatcgcaagc
    15661 gatgccgcgg gtaatcagaa aaactcgtta cccattaccg ttacgatcga cagtacgctg
    15721 acggtgccgg agattgcgtt ggcagcaggt gaagacaatg gcgtttcaga cagcgataac
    15781 gtgacgaatc acacccagcc taagttcacg ctgcagcata ttgatgctga tgtgaccggg
    15841 gtgaccgtaa acgtgacgca taacggcgtg acagacacct atcaggcgac gcaaggcgcg
    15901 gatggctgga ccttcacgcc gccagccgcc tggaatgatg gtacctacac gctgagcgtg
    15961 acggtggtgg atcgcgcggg gaactcacag caatctgctt cgctagcggt gacggttgac
    16021 tcaacggtga cggtaacagc ggatagccag catgacgatg cgagcgatga cgccacgcca
    16081 acagcggtta ctccaccgga gtctgaaaca gtgaatgccg aaagcgatac gcatcttcgt
    16141 acagtgccgt ctgcggcgga agaaagcgtg gtgaaggaga cggcctatag tattacattg
    16201 ttaaacgcta actctgggga tgaaatagat cgttcaatta gtcagacacc ttcttttgaa
    16261 atatcagtac ctgagaatat tgttaatgtc agtgttatgt ttgaaggaga agagtttact
    16321 ctgccgataa ctaaccagaa agcaatattc gaagttccgc tatctttgga agatggtgaa
    16381 tatactatgg acgtgaaatt cattgataag gacgatgatt tcctgattaa ggaaaaaaca
    16441 ttctcagtcg atcactcctc ggcggatatt gtgaacgcaa tgaatgcaag aggaaagacc
    16501 gaggatgata ttaatgattc cccttccacg agttctgtag ggcacaacaa taacggcgct
    16561 attgatgttt tcgccgttaa tgaagttacg ctacctgtag ataatcaaga agaacacgca
    16621 taataacgga ggcccctcac ctttgggtga gggggtttac ttatggataa aaaactagaa
    16681 ccttattatt taagtgcgga aacggcatta tctatagtgt ctaaaaaatt caacataaaa
    16741 attgacatca aagaggatga tataaattta aga
//
LOCUS       DAJVKX010000095        16553 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000095 DAJVKX010000000
VERSION     DAJVKX010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16553
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.095"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(62..880)
                     /gene="cof"
                     /locus_tag="OPY25_003150"
     CDS             complement(62..880)
                     /gene="cof"
                     /locus_tag="OPY25_003150"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HCS0928701.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGRETIATLSRLRERDITLTFATGR
                     HVLEMRHILGTLSLDAYLITGNGTRIHSLEGDVLHRQDLDPQVADTVMHHAWDTRASM
                     HVFNDNGWFTGQEIPALLQAHVYSGFRYQVIDIKSIPAHQVTKICFCGDHDDLIRLRI
                     QLNEALEERAHLCFSAVDCLEVLPLGCNKGSALAVLSNHLGLSLADCMAFGDAMNDRE
                     MLGSVGRGLIMGNAMPQLIAALPHLSVIGHCGNQAVSHFLTHWLDNPHLPYSPE"
     gene            980..2680
                     /locus_tag="OPY25_003151"
     CDS             980..2680
                     /locus_tag="OPY25_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HCS0928702.1"
                     /translation="MRLLNRLNQYQRLWQPSAGETQHVTVSELAERCFCSERHLRTLL
                     RQAQQAGWLRWEAQSGRGKRGRLQFLVTPESLRTAMMEQALEKGQQLNVLELAQLAPG
                     ELRAMLQPFMGGQWQNDTPTLRIPYYRPLDPLQPGFLPGRAEQHLAGQVFSGLTRFDR
                     DSQYPCGDLAHHWKVSADGLRWDFYIRSTLHWHNGDAVDTAQLHERLERLLTLPALSK
                     LFISVARIEVTHPQCLTFLLHRPDYWLAHRLASYCSGLAHPDLPLIGTGPFRLALFTP
                     ELVRLESHDHYHLSHPLLKAIEFWITPQLFAQDLGTSCRHPVQIAIGKPEELATLSQV
                     SSGISLGFCYLTLKKGSRLNVQQARRLIHIIHHTSLLKTLPVDENLIMPSQGLLPGWT
                     IPQWQDVDETPLPKKLTLAYHLPVELHTMAEQLRHYLATLGCELTLIFHNAKNWNNCP
                     ALAQADLMMGDRLIGEAPEYTLEQWLRCDQIWSHVLDAPAFSHLQATLDALQIQPNEK
                     DRRAALQQVFANLMDDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFSEAWLPPPSP
                     "
     gene            2745..3440
                     /gene="queC"
                     /locus_tag="OPY25_003152"
     CDS             2745..3440
                     /gene="queC"
                     /locus_tag="OPY25_003152"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HCS0928703.1"
                     /translation="MKRAVVVFSGGQDSTTCLAQARHQYDEVHCVTFDYGQRHRAEID
                     VARALALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPNADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVNLGMAKDIRFETPL
                     MWIDKAETWALADYWGQLDLVREETLTCYNGIKGDGCGHCAACNLRANGLNHYLSNKA
                     AVMAAMKQKTGLR"
     gene            complement(3547..3945)
                     /gene="fadM"
                     /locus_tag="OPY25_003153"
     CDS             complement(3547..3945)
                     /gene="fadM"
                     /locus_tag="OPY25_003153"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HCS0928704.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWM
                     TARNIAFVVVNININYRRPAVLSDLLTVTSQVQQLNGKSGVLSQTITLEPEGQVVADA
                     LITFVCIDLKTQKALPLEGELREKLEQMVQ"
     gene            complement(4049..4423)
                     /locus_tag="OPY25_003154"
     CDS             complement(4049..4423)
                     /locus_tag="OPY25_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCS0928705.1"
                     /translation="MKHGIKALLITLSLTCAGMAHSALAATPVAKNAAVETKADTPSS
                     SSAKAALPAKASDDEGTRVSINTASAEDLARVMNGVGLKKAQAIVSYREEYGPFKTVD
                     DLKQVPGMGSALVERNLAVLTL"
     gene            complement(4573..6444)
                     /gene="ppiD"
                     /locus_tag="OPY25_003155"
     CDS             complement(4573..6444)
                     /gene="ppiD"
                     /locus_tag="OPY25_003155"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCS0928706.1"
                     /translation="MMDSLRTAANSLVLKIIFVIIIVSFILTGVSGYLIGGSNNYAAK
                     VNGQEISRAQFENAFNNERNRMQQQLGDRYSELAANEGYMKSLRQQVLNRLIDEALLD
                     QYSRELKLGISDEQVKQAIFATPAFQVDGKFDNNRYNAIVNQMGMTADQYTQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVSQQRVVREAVIDVNALAAKQQVTDQEVSSYY
                     DQNKVRFMTPEQFRVSYIKLDAATMQAPVSDADIQAYYDQHVDQFTQPERIRYSIIQT
                     KTEDDAKAVLDALNKGEDFATLAKEKSTDIISARNGGDMGWLEESATVPELKNAGLKE
                     KGQISGVIKSSVGFLVARLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQKVS
                     DAASNDNESLAGAEQVAGVKAVETGWFSRDTLPEELNFKPVADAIFNGGLVGENGTPG
                     PNSDIITVDGDRAFVVRVSEHKPEAVKPLAEVKEQVTALVKHNKAEQQAKLDAEKLLV
                     ELKAGKGAEAMKAAGLSFGEPKTLSRTSQDPVSQAAFALSLPTKDKPVYGVANDMQGN
                     VVLLAFDEVKAGAMPEAQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            complement(6735..7007)
                     /gene="hupB"
                     /locus_tag="OPY25_003156"
     CDS             complement(6735..7007)
                     /gene="hupB"
                     /locus_tag="OPY25_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HCS0928707.1"
                     /translation="MNKSQLIEKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            complement(7215..9569)
                     /gene="lon"
                     /locus_tag="OPY25_003157"
     CDS             complement(7215..9569)
                     /gene="lon"
                     /locus_tag="OPY25_003157"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HCS0928708.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLDSPAIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRSLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADSENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            complement(9755..11026)
                     /gene="clpX"
                     /locus_tag="OPY25_003158"
     CDS             complement(9755..11026)
                     /gene="clpX"
                     /locus_tag="OPY25_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HCS0928709.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLTGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKA
                     KSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALVQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALNAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIAGQSKPLLIYGKPEAQASGE"
     gene            complement(11278..11901)
                     /gene="clpP"
                     /locus_tag="OPY25_003159"
     CDS             complement(11278..11901)
                     /gene="clpP"
                     /locus_tag="OPY25_003159"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCS0928710.1"
                     /translation="MSYSGERDNLAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMAHHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            complement(12148..13446)
                     /gene="tig"
                     /locus_tag="OPY25_003160"
     CDS             complement(12148..13446)
                     /gene="tig"
                     /locus_tag="OPY25_003160"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCS0928711.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFVDAIIKEKINPAGAPNYVPGEYKVGED
                     FTYSVEFEVYPEVELTGLESIEVEKPVVEVTDADVDVMLDTLRKQQATWKEKDGAADA
                     EDRVTIDFTGSVDGEEFEGGKATDFVLAMGQGRMIPGFEDGVKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFVINLKKVEERELPELTEEFIKRFGVEDGSVAGLRAEVRKNMER
                     ELKGAVRNRVKSQAIEGLVKANDIDVPSALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVSEKATSFNELMNQQA"
     gene            complement(13793..14110)
                     /gene="bolA"
                     /locus_tag="OPY25_003161"
     CDS             complement(13793..14110)
                     /gene="bolA"
                     /locus_tag="OPY25_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HCS0928712.1"
                     /translation="MMIREQIEEKLRTAFDPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYGTLTAELSTTVHALALHTYTLKEWEGLQDTIFASPPCRGAG
                     SIA"
     gene            14414..14992
                     /locus_tag="OPY25_003162"
     CDS             14414..14992
                     /locus_tag="OPY25_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0928713.1"
                     /translation="MLKKLLFPLVALFMLAGCATPPTTIDVAPKITLPQQDPSLMGVT
                     VSITGADQRQDQALAKVTRNNQLVTLTASRDLRFLLQEVLEKQMTARGYMIGPNGAVN
                     LQIIVNQLYADVSQGSVRYNIATKADIAIIATAANGNKMTKNYRANYSIEGAFQASNQ
                     NIADAVNSVLTDTIADMSQDTSIHDFIKQNAR"
     gene            15036..16511
                     /gene="ampG"
                     /locus_tag="OPY25_003163"
     CDS             15036..16511
                     /gene="ampG"
                     /locus_tag="OPY25_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HCS0928714.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFLGRRRGWLLATQLLLLAAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADRWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPSPKSLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKNMFSMGAAVFFENLCGGMGT
                     AAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWPTFYLFSVVAA
                     VPGLLLLLVCRQTLEYSWQSERFIPRTQYRGTYNFALSILLAGVALLAVWVLLLTMNA
                     LDYTNFSFLPELLETAVAIAVCGIVFGGLLDYLALRKTRLL"
BASE COUNT         3680 a         4638 c         4032 g         4203 t
ORIGIN      
        1 tgggggtttt ccatagacaa aaaaagccag actgaatgtt tggcttgctg gaagagatct
       61 ctcattcggg ggaataaggt agatgcggat tgtccagcca atgcgtcaaa aagtgtgata
      121 ccgcttgatt accacaatgt ccgataaccg aaaggtgtgg cagcgcggcg ataagctgcg
      181 gcatggcatt gcccataatg agcccccgcc cgacgctgcc cagcatttcc cgatcgttca
      241 tcgcgtcgcc aaacgccatg caatctgcca gtgaaagccc taaatggttg ctcaataccg
      301 ccagcgccga tcctttattg caccccagcg gtagcacttc caggcagtcg acggcagaga
      361 aacagaggtg cgcgcgttct tccagcgcct cattgagctg aatgcgcaaa cggatcagat
      421 cgtcatgatc gccgcaaaaa cagatcttcg tcacctgatg ggccggaata ctttttatat
      481 cgataacctg ataacgaaag ccgctgtaga cgtgcgcctg gagtagcgcg gggatctcct
      541 ggcctgtaaa ccagccgttg tcattaaaca catgcatact ggctcgggta tcccaggcat
      601 ggtgcatcac cgtatcggca acctgaggat cgagatcctg acgatgcagc acgtcgcctt
      661 ccagcgagtg aattcgcgtc ccgttaccgg taataagata agcatccagt gaaagcgtcc
      721 ccagaatatg ccgcatctcc agcacgtgac gacccgtagc gaatgtcaga gtgatatcgc
      781 gttcgcgcag acgcgacagc gtggcgatcg tttctctacc caaatggtga tcgggcatta
      841 ataacgtgcc atccatatca aatgctgcca gacgggccat ctctttctcc acactgtaac
      901 gcggttaact tgttgttcag tattacctga gatatacgga agtaatagtg aacagataaa
      961 aggaagtgtt ccgggtttta tgaggctact gaatcggctt aatcaatatc aacgcctctg
     1021 gcagccttcc gccggggaaa cgcaacatgt caccgttagc gaactggccg aacgctgttt
     1081 ttgtagcgag cgccatctgc gaacgctgct gcgtcaggcc cagcaggcgg gttggctaag
     1141 atgggaggcg cagtccgggc gcgggaaacg tggacggctc cagtttctgg tcacgccgga
     1201 atcgctccgc accgccatga tggaacaggc gctggaaaaa gggcagcagc tcaacgtact
     1261 ggaactggcg cagctggcgc ctggcgagtt acgggcgatg ctccagcctt ttatgggcgg
     1321 ccaatggcaa aacgatacgc caacattgcg tattccctac tatcgtccgc ttgatccgct
     1381 gcagccgggt ttcctgccag gacgcgcgga acagcatctc gcagggcaag ttttttccgg
     1441 gttaacgcgc ttcgatcgcg atagccaata tccttgcggg gatttggcgc atcactggaa
     1501 ggtttccgcc gacggtttac gctgggattt ttatattcgc tccacgctgc actggcataa
     1561 tggcgatgcg gtggataccg cgcagttaca cgaacgcctg gaaaggctgc ttaccctacc
     1621 ggcgctaagc aaattgttta ttagcgtcgc acggatcgaa gtaacgcatc ctcagtgcct
     1681 gacctttctc cttcaccgac ctgattactg gctggcgcat cgtctggcga gctattgtag
     1741 cggtctggcg catcctgacc tgccgcttat cggcaccggt ccttttcgcc tggcgttgtt
     1801 cacgccggaa ctggtgcgtc tggaaagtca tgaccattat cacctcagcc atccgctgct
     1861 gaaagcgatt gaattctgga tcaccccgca actgtttgcc caggatctgg gcaccagttg
     1921 ccgccatccg gtgcagattg ccatcggcaa accggaagag ctggcgacgc tgagtcaggt
     1981 aagtagtggt atcagtcttg gcttttgtta tttaaccctc aaaaagggct cacggctcaa
     2041 cgtacagcag gcgcggcgtc tgatacatat tatccatcat acttcgctgc tgaaaacctt
     2101 accggtagat gagaacttga ttatgccaag tcaggggctg ctacccggct ggacaatccc
     2161 gcaatggcag gacgttgatg aaacaccatt gccgaaaaaa cttaccctgg cgtatcacct
     2221 tcccgtagag ctgcatacga tggcggaaca gcttcgacat tacctggcga cgctcggctg
     2281 tgagttaacg ttgatttttc ataatgccaa aaactggaat aactgccctg cgttggcgca
     2341 agcggatctg atgatgggcg acaggctgat cggcgaagcg ccggaatata cgctggagca
     2401 gtggctacgt tgcgatcaga tctggtcaca tgtcctggac gcgcctgcgt tttcccatct
     2461 gcaggctacg cttgacgctc tgcaaattca gcccaatgaa aaagatcgcc gcgccgcgct
     2521 acaacaagtt tttgccaacc tgatggatga cgccacactt acgccgctgt ttaattatca
     2581 ctatcgcatc agcgccccac cgggcgttaa cggcgttcga ctcacccctc gcggctggtt
     2641 tgaatttagc gaagcctggc ttccgccgcc ttcgccgtga agaagctggt cgggattatc
     2701 cgtacgcgtt accatattgg ctttcgtcat tgatcaggat aactatgaaa cgcgccgttg
     2761 ttgtatttag tggaggtcag gactccacca cttgtctggc gcaagcgcgg catcagtatg
     2821 atgaagtgca ttgtgtcacg tttgattatg gtcagcgcca ccgcgcagag attgatgttg
     2881 cgcgcgcact ggcgttaaaa cttggcgcac gcgcgcataa agtgctggat gtcactttgc
     2941 tgaacgaact ggcggtcagc agcctgacgc gggatagcat tccggtgccg gactatgaac
     3001 cgaacgctga cggtatcccc aacactttcg taccgggacg caatattctc tttctgacgc
     3061 tggcggcgat ttacgcttat caggtcaaag ccgaggcggt gatcaccggc gtttgcgaga
     3121 ccgatttttc cggctatcca gactgtcgcg atgagttcgt caaagcgctg aatcacgcgg
     3181 tgaatctggg catggcgaaa gatatccgtt tcgaaacgcc cctaatgtgg attgataaag
     3241 ctgaaacctg ggcgctggcc gattattggg gccaactgga tttagttcgc gaagagacgc
     3301 tgacctgcta taacggcatt aaaggcgatg gctgtggtca ttgcgcagcc tgtaatctgc
     3361 gcgctaacgg cctgaatcat tatctgtcga ataaagcggc ggtgatggcg gcaatgaagc
     3421 aaaaaaccgg gttaaggtga ttgttttgcc ggatggcggc gcacgcacct tatccgtgcc
     3481 tggcgatatg caccatggtc aatatcgcca ggccggacaa gttcaacgcc atcagacagc
     3541 gaggcgttat tgcaccatct gttccagctt ttcacgcaat tcgccttcca gcggcagcgc
     3601 tttttgcgtt tttaaatcaa tacaaacaaa cgtgatgagc gcatcggcca ccacctgccc
     3661 ttctggctcc agcgtaatcg tctggcttaa tacgccgctt ttaccgttaa gctgttgtac
     3721 ctggctggtc acggtcagta gatcgctcaa taccgccggg cgacggtaat ttatattgat
     3781 gtttaccacc acaaaggcaa tattgcgggc cgtcatccac tgaaagctgt cgctgttttc
     3841 cagcccatcc caacgggcct cttccagaaa ttccagatag cgggcattat taacatgttg
     3901 ataaacatca agatgatatc cacgaacttt gatttgtgtt tgcatagcgc aataacctta
     3961 cgttgttgtt ataagtaagc gacaagtaca gaggtcataa ctggtatgac ctctacagtc
     4021 tggcaaattt tggccactgt gcaagtgatt acaatgttaa aactgccaga ttacgctcca
     4081 ccagcgcgct tcccattccc ggcacctgct ttaaatcatc caccgtttta aaaggaccat
     4141 actcctcccg atagctcaca atagcctgcg cttttttcag cccaacgccg ttcatcaccc
     4201 gcgccagatc ctccgcagac gcggtattaa tgctcaccct agtaccttca tcatcgctgg
     4261 ctttagcagg taatgccgct ttggcggagg atgaagaagg cgtatccgct tttgtttcca
     4321 ccgctgcatt ttttgcgaca ggcgtcgccg ccagcgcgct atgggccatg cccgcgcagg
     4381 ttaaagaaag cgtaataagc agtgctttaa ttccgtgttt catactgttt tctccttgtt
     4441 tgttaacagt gcagccacga tagcggggcg gagaaaaacg aacaaatggc aattctcaga
     4501 aatggaaaag gccgcgaaag cggcctttgt gggatacaac gttttgcaat tttttgcgaa
     4561 gcgcctcgac gattactgct gttccagagc gtcgccgatt ttgattttcg cctctttacg
     4621 cagattgctc atcagcgcct caaagacaat ttgcgcattg ttctgcgtga tgccctgcac
     4681 catcgctttt ttctgcgctt ccggcatggc gcccgctttc acctcgtcaa acgccagcag
     4741 aacgacgtta ccctgcatat cgttcgccac gccataaact ggcttatctt tcgtcggaag
     4801 gcttaacgca aaggccgcct gactcaccgg atcctgactg gtacgactta acgttttagg
     4861 ctcgccaaaa ctcagacccg ccgctttcat cgcttccgcg cctttgcccg ctttcagctc
     4921 gaccagcagt ttttccgcat ccagcttcgc ctgttgttcc gctttgttat gcttcaccag
     4981 ggcagtgacc tgttctttca cttctgccaa cggcttcacg gcttcaggtt tatgttcgct
     5041 cacgcgcaca acaaaagccc ggtcgccatc tacggtgata atgtctgaat tcggccccgg
     5101 cgtaccgttt tcgcctacca gaccgccatt aaagatagca tcggctaccg gtttgaagtt
     5161 cagctcttcc ggtaaggtgt cacggctaaa ccagccggtt tcaacggctt ttacgccagc
     5221 gacctgttca gcgcctgcta acgactcatt gtcgttgctt gccgcatcgc tcaccttctg
     5281 ctgcaacgca tagtaagcat ccagcgcttt ttcctgtttc actttcgcgg caatgtcgtc
     5341 gcgaacctcg cttaacggtt tcactttggc aggctgaata tcatccagac gcgccaccag
     5401 aaaaccgaca gacgacttaa tcacgccaga tatctggcct ttttctttta atccggcgtt
     5461 tttcagttcc ggcaccgtgg cagactcttc cagccagccc atatcgccgc cattacgcgc
     5521 agagatgata tcggtagatt tctctttcgc cagcgtggcg aaatcttcgc ccttgttcag
     5581 cgcatccagt accgctttcg catcatcttc cgttttggtc tgaataatgc tgtaacgaat
     5641 gcgctccggc tgagtaaact gatctacatg ctggtcataa taggcctgaa tatccgcatc
     5701 gctgaccggt gcctgcatcg tcgcggcatc cagcttgata tagcttacgc ggaactgttc
     5761 cggcgtcata aagcggactt tattctgatc gtagtagctg gacacttcct gatcggtcac
     5821 ctgctgcttc gccgccagcg cgttgacatc aataacggct tcacgcacca cgcgctgttg
     5881 agagactaat gccgccagtt cgtcggtttc ccctttcagc ataaaatcag taccggccac
     5941 gccgttgatc agttgctgag tggtaagctg gttacgcagc gcctgagtat actgatcggc
     6001 cgtcattccc atctgattca caatcgcgtt atagcggttg ttgtcaaact taccgtccac
     6061 ctgaaaagcg ggagtggcga aaatcgcctg ctttacctgc tcatcgctga tgcccagttt
     6121 cagttcgcgg gaatattgat ccaacagcgc ttcatctatc agacgattca gcacctgctg
     6181 gcgcaggctt ttcatataac cttcgttggc cgccagttca gaatacctgt cgcccaactg
     6241 ctgctgcata cggttacgtt cgttgttaaa cgcattctca aactgtgccc ggctgatttc
     6301 ctggccattc acttttgcgg cgtagttatt gcttccgcca atcaggtaac cactaacgcc
     6361 ggtcaaaatg aacgacacga taatgataac gaaaataatc ttgagcacga gactgtttgc
     6421 agccgtgcgt aagctgtcca tcatggtgta accacactcc gctgtaggtg actttacact
     6481 ttatctttca ggcggcttct ctgctggcta ctgagtgctt cgctcagtag ccgcgtcgac
     6541 gcaacctgaa tgatttgcgt atatagactt cacgcgcatc gcattttctg aacgcggcgc
     6601 acaaaagcct attgtgacaa gaaacgaggg caattgtcag cccgcaacgc acagaaagtc
     6661 ccgaatcgcc aataaaaaag gcacatcagt tgatgcgccc ttgtactttg tcacatcccc
     6721 cgaggggatc acgcttagtt taccgcgtct ttcagcgctt tacctgcacg gaaactcggc
     6781 actttggcag cggcgatggt gatctcttta cctgtttgcg ggttgcgacc agtacgggca
     6841 gcacgctctt taacagcaaa agtaccaaag cctaccagtg caacgtcatc cccttctttc
     6901 agagattcgg taacagaagc aataatcgca tctaacgcac gtccagccgc agccttagag
     6961 atatcagccc ctgcagcaat tttttcgatc agttgagatt tattcactct tctcttcctc
     7021 tttataattt atatcgcacc tgaatccttc gaagtacgac cgcgcagcag ttatatcagg
     7081 cctgccacgc ccttacaaca cccgttaatg gtggcagacc caatcaacca tctaaattag
     7141 ctatacaaaa aaggctggca agtccgaaat agcctgccag ccctgttttt attagcgcta
     7201 tttgcgcgag gtcactattt tgcggttaca acctgcattc cagacggttc gttttgcaga
     7261 gcaagcgtca gaacttcctc aatgcgcttc acaggatgaa tatccagatc ggcaatcacg
     7321 ttgtccggaa tttcctccag atcacgttta ttttcgaatg gaattaagac cgttttaatc
     7381 ccgccgcgat gcgccgccaa cagtttttct ttcaggccgc cgatcggcaa cacctgacca
     7441 cgcagcgtga tctcaccggt cattgccaca tctgcgcgca ccggattacc ggtcaggcag
     7501 gaaaccagcg cggtacacat cgcgataccg gcgcttggac cgtctttcgg cgttgcgcct
     7561 tccggcacgt gaacgtggat atcgcgtttt tcgtaaaagt ccggattaat acccagtttt
     7621 tccgcgcgcg cgcgcaccac ggtcagcgcc gcctgaatag attcctgcat cacttcaccg
     7681 agcgagccgg tgtaggtcag cttgcctttg cccggtacgc aggcggtttc gatggtcaac
     7741 agatcgccgc ccacttccgt ccacgccagc cccgtcacct gacccacgcg gttttcgcta
     7801 tccgcgcggc cataatcaaa gcgctgcaca ccgaggtagt cgtgcagatt atcgccgtta
     7861 atttcaatat gttttaacga cttatcgagc aacagttgtt taaccgcttt acggcacagt
     7921 ttggagattt cacgctccag actacgaacg cccgcttcac gcgtgtaata gcggataata
     7981 ccgataatcg cgctatcgtc gaccgtcagt tcgcctttct tcagcgcgtt acgctcgatc
     8041 tgcttcggca gcaggtgacg tttagcaata ttcagcttct cgtcttcggt ataaccggac
     8101 agacggatca cttccatacg atccagcagc ggcgccggaa tgttcatgga gttggaggtg
     8161 gcgacgaaca tcacatcgct gagatcgtaa tccacttcca ggtaatgatc gctgaacgcc
     8221 acgttctgct ccgggtccag cacctcaagc agtgcggaag ccggatcgcc gcgcatgtcc
     8281 gaggacattt tgtcgatctc atcgagcagg aatagtgggt ttttaacccc cactttggcc
     8341 attttttgga tcagtttacc cggcatagag ccaatgtaag tccggcgatg accgcggatt
     8401 tccgcttcat cacgcacgcc gcccagcgcc atacggacgt atttacgccc tgtggcttta
     8461 gcgatggact ggcccaacga ggttttacct acccccggcg gccccaccag acacaggatc
     8521 ggccccttga ttttatttac acggctttgt accgcgagat actcaaggat gcggtctttc
     8581 acacgctcca gaccataatg gtcagtatcg aggatttcct gcgcctgacg caggtctttt
     8641 ttgaccttgc tacgcgcatt ccacggcacc tgcaccatcc agtcgatgta gccgcgcacc
     8701 acggtcgctt ccgccgacat cggagacatc attttcagct tctgcagttc cgcttccgct
     8761 ttctctttcg cctctttcgg cattttcgcc gcgtcgatct tacgcttcag cgcttcgttt
     8821 tcgtccggcg cgtcgtccat ctcgccaagt tctttctgaa tcgctttcat ttgctcgttc
     8881 agatagtact cgcgctggga tttctccatc tgctttttca cgcggttgcg aatgcgtttc
     8941 tcaacctgca gcagatcgat ttcagattcc atcatcgcca tcagatattc cagacgttcg
     9001 ttaacgtcgg acatctccag tacggactgt ttatccgcca gtttcagcgg catatgcgcg
     9061 gcgatggtgt cagccagacg tgcagggtcg tcaatgctat tgagtgacgt cagcacttcc
     9121 ggcggaattt ttttgttcag cttgatgtag ccttcgaact ggctgatagc ggtacgcacc
     9181 agcacttctt gttcacgctc atcaatggct ggcgaatcaa ggtactccgc cttcgcggag
     9241 aaatgttcgc cgttgtcaga cagcgcggaa atacgcgcgc gctgtaaccc ctcaaccagc
     9301 acttttacgg tgccgtcagg cagtttcagc atctgcaaaa tagaggccac ggtcccgacg
     9361 gtgaaaagat cgtttacacc cggctcatcc gttgatgctt ccttctgggc gaccagcatg
     9421 atttttttat catggtccat agccgcttcc agacaacgga tagatttttc ccgccctaca
     9481 aataagggta tgaccatgtg cggataaacc accacatcgc gcaagggcaa tacggggatt
     9541 tcaatgcgtt cagaacgctc aggattcata gagctctctc ttagtttagt gtccgccagg
     9601 taatcagata gtatagctgt gctccatacc acctataaca tgtacgtcag tatatgggga
     9661 tgtttcccac acattcaacg gcgtgtttac aggaaaaacg aaaggggaga taaaatcccc
     9721 ccttttttgg ctaactgatt gtatgaatgt ttaattattc gccagaagcc tgcgcttccg
     9781 gtttgccgta aatcagcaac ggcttactct gaccggcaat aacggactcg tcaatcacca
     9841 ctttttcgac gtcttccata gatggcaaat cgtacatggt atccagcagc gccgcttcga
     9901 cgatagaacg caggccacgg gcaccagttt tacgcgccat cgctttcctg gcgatagcgt
     9961 tcagcgcttc gtcacggaat tccagatcga cgccttccag gttaaacagc gcctgatact
    10021 gcttggtcag cgcatttttc ggctctttca ggatttgaac cagcgcttct tcgctgagtt
    10081 cgttcagcgt cgccaccact ggcagacgac cgataaactc aggaatcaga ccaaatttga
    10141 tcaaatcttc cggttcaacc tgcgacaaca gctcgccttc actggctttg tcggacttcg
    10201 ctttcaccgt cgcgccaaaa ccaatgccgg agccggtttc aacacggtta gcgatcactt
    10261 tatccagacc ggcaaacgcg ccgccgcaga taaacagaat cttagaggta tctacctgta
    10321 agaactcctg ctgcggatgt ttgcgaccgc cctgcggtgg aaccgcggcg acggtgcctt
    10381 cgatcagttt cagcaacgcc tgctgtacgc cttcgccgga aacatcgcgg gtaatggacg
    10441 gattgtctga tttacgcgaa atcttatcga tttcatcaat gtagacaatc ccacgctgcg
    10501 ctttttgcac gtcgtagtcg catttctgca acagtttctg aatgatattc tcgacgtctt
    10561 cccccacgta acccgcttcg gtcagcgtgg tcgcatccgc catagtgaac ggcacatcca
    10621 gcaagcgcgc cagcgtttcc gccagcagcg ttttaccgga accggtcggt ccagtcagca
    10681 gaatgttgct tttgcctaac tcgacgccat tgctggtatc gccgttacgc agacgcttgt
    10741 agtggttata gaccgccacc gccagcactt ttttcgcctg ctcctggccg ataacgtaat
    10801 cgtccaggtg agtacgaatt tcatgcggcg tcggcagcgc actacgttca cggtgcggag
    10861 caacttcttt aatttcttcg cgaataatgt cgttacataa atcgacgcat tcgtcgcaga
    10921 tatacacgga tggaccggca atcagcttgc gcacttcatg ctggcttttg ccgcaaaaag
    10981 agcagtacaa caatttgccc gagccatctt tgcgtttatc tgtcatgagt caaaacctct
    11041 tctttgttct ttgtgccgca cacgacgacg caaatgccat tctcaggcgc aagccgctaa
    11101 tcagcgttgt gccgcccttc attagtatat acacaaaatc attcgagcta catcaaggcg
    11161 gcaactcagc gactccgcag gcgcttacat aagtaagtca ctgggaggcg cgctggcaac
    11221 caacaccgag gtagcgtgaa ggatgaagtg tatagcggca cacttgcgtc cagggcatca
    11281 attacgatgg gtcaaaattg agtcaaccaa accgtactct accgcttcag gcgcggagag
    11341 gaagcgatcg cgctcagtat cacgttcaat ctgctcaaga gattgacccg tatgatgcgc
    11401 cataagttca ttcatgcgcc cttttacttt caaaatttcg cgggcgtgaa tttcaatatc
    11461 cgtcgcctgg ccctgatagc cgcccagcgg ctggtggatc atgacgcgag agttcggcaa
    11521 gcagaaacgt ttgcctttcg ccccggcagt cagcagaaac gcccccatag aggccgcctg
    11581 tcccatacaa atggtgctga cgtctggctt aataaactgc atggtgtcat agatggacat
    11641 ccccgcagta attacgccgc caggagaatt aatgtacaga tagatatctt tttccgggtt
    11701 ttccgcttcc aggaacagca tctgcgccac gatcaggtta gccatatggt cttcgacctg
    11761 gccggtcaga aatatgacgc gttccttaag tagacgagaa tagatatcaa aagagcgctc
    11821 accgcgtgag gtctgttcaa tgaccatcgg caccagcgcc atatgagggg ccaaattatc
    11881 tcgttctccg ctgtatgaca tttccgtctc ctggataaaa attgaaaaaa tctgctgtac
    11941 tgattgtaac ctgatggacg gattatcagc cagtccctct gtaatgggta cggcatcgcc
    12001 ataattcaag cataacaatc ttttgctcta acgctaacac tgaaacgcgg ttttcgcacc
    12061 cttaccacgc aaaatgcgtg acaaaaaaaa cccgtcactg aaaggtgacg ggtttttgtg
    12121 caaatttcgt gcttttaacg cgaaaaatta cgcctgctgg ttcatcagct cattgaagga
    12181 agtggctttt tcagacactt tcgcttttgc cagaaccgct tcaacagcct gttcttccag
    12241 agcgacgtta cgcatattgt ccatcagctc tttatttttg ctgtagaact caatcacttc
    12301 tttcggatct tcgtaagcag aggccatctc ttcgatcagg cctttaacgc gttcttcgtc
    12361 cgctttcagc tcgttggtac gaatgacttc gccgagcagc agaccgacaa ctacacgacg
    12421 cttagcctgt tcttcgaaca gttcgcgcgg cagctccaga gcctgtttct cgttaccacc
    12481 aaaacgctgc gcagcctgac gacgcagaac gtcgatttcg ctgtcgatca gcgcagacgg
    12541 tacgtcgatg tcgttagctt ttaccagacc ttcgatcgcc tgagacttaa cgcggttacg
    12601 caccgcgcct ttcagctcgc gttccatgtt tttacgtact tcagcgcgca gaccggctac
    12661 ggaaccatct tcaacgccga aacgtttgat gaattcttcg gtcagttccg gcagttcgcg
    12721 ttcttcaact ttcttcaggt tgataacgaa cttagccgct ttacctttca ggttttcagc
    12781 gtggtactct tccgggaagg tcacatcgat agtgaactct tcgccagctt tgtggccttt
    12841 aacgccgtct tcaaagcccg gaatcatacg accctggccc atcgccagaa cgaaatcggt
    12901 cgctttgccg ccttcgaact cttcgccgtc tacagagccg gtgaaatcga tggtcacgcg
    12961 gtcttccgca tccgcagcgc cgtctttttc tttccaggtc gcctgctgct tacgcagggt
    13021 gtccagcatc acatcaacgt cagcgtcggt gacttcaaca accggctttt caacttcgat
    13081 ggattcgagg ccagtcagct caacttccgg atagacttca aactcgacgg agtaagtgaa
    13141 gtcttcaccc actttgtatt cgcccggaac atagttcggc gcgcctgccg ggttaatttt
    13201 ttctttgatg atcgcgtcaa cgaagttgcg gctcatcaga tcgcccagca cgtcctggcg
    13261 aacagaagcg ccataacgct gagcgacgat attcatcggt actttgcctt tacggaagcc
    13321 gtcaatacgt acttttttcg ctacgttgac cagctcgctt tttacagcgg tctcgatgct
    13381 gtcagcagcg attgtaatcg ttacacggcg gccaaggccc tgagtggttt caactgaaac
    13441 ttgcatcttg ttacctcaaa aaatcacagt gctcggtcaa ctctactccg caagcacgtg
    13501 ctatttgctt cgcggaaccg ggatgttctc ataatcaatc acattccctg tcgtcagaat
    13561 catcccgaag acgttcatat ataagacggc gcattatagc ggcatcactt ttgtgagtcg
    13621 agaacggtga ttgtgcgatg ctgcggcggt tttcacaatt ctcggctaat ttttgtctga
    13681 atactgtacg acacgctcaa aattcagaca aaataaaacg gcccgcaggc cgttttcaca
    13741 taattctgta gcaacatact ggaaaagcgg aggtagttgc aaatccgttt tgctacgcga
    13801 tgcttcccgc gccgcgacaa ggaggcgacg cgaagatagt atcctgcaat ccttcccact
    13861 ctttgagggt ataagtatgc agtgccagcg catgtacggt tgtggaaagt tccgccgtta
    13921 acgtaccgta aatcatccga tgacgattaa gaaaacgttc gcctgtaaag cgatcgctca
    13981 ccagcacgac cttaaaatgg ctttccgatc ctgctggaac attgtgacga tagctttcat
    14041 ccacaacttc gagaaacacg gggtcgaacg ctgtccttaa tttttcttct atttgctcac
    14101 gtatcatcat gaaaatctcc tccgacaacg ctgtgatgtc acccatccct ttaaatacta
    14161 gccgctttta ccgtttccat tacagcatga caacaaaaat ttagctttcg tctgattatt
    14221 tcagccaaac gtatgaagtt tactgcctta atcattcttt tagcgctcaa aatccccgct
    14281 cgcgccgtta tcaataccaa atcggacatt acgacgaatt tacctgcgtt gaccacttcc
    14341 cctcgccgtt agcggtgtta tgatggcggg aatttttacc tatcacgttt taagcgtcat
    14401 tgagagcctg aatatgttaa aaaaacttct ctttccgtta gtcgctctgt ttatgctggc
    14461 aggatgcgcc acaccgccga cgaccattga cgtcgcgccg aagatcacct tgccacagca
    14521 ggacccgagc ctgatgggcg tcaccgttag cattaccggc gcggaccaac gccaggatca
    14581 agcgttagcg aaagtcacgc gtaacaacca gttggtaacg ttaaccgcct cccgcgattt
    14641 acgcttcctg ttacaagaag tcctggaaaa acagatgacg gcgcggggct atatgatcgg
    14701 gcctaacggc gcggttaatc tgcagattat tgttaaccaa ctgtatgctg atgtttccca
    14761 gggcagcgtg cgctacaaca tcgcgaccaa agcggatatc gcgattattg cgaccgcggc
    14821 aaatggcaac aagatgacca aaaactatcg cgccaactac tctattgaag gggcgttcca
    14881 ggcctctaac cagaatattg ccgacgcggt gaacagcgtt ctgaccgata ccattgctga
    14941 tatgtctcag gacaccagca ttcacgattt tatcaagcaa aacgcccgtt aatagcaaca
    15001 acaagacccg gcagaagccg ggtctgtaga tgcctatgtc aagtcaatat ttacgtattt
    15061 tccagcaacc gcgttcagcc attctgctga tattgggttt tgcctccggt ctcccgctgg
    15121 cgctcacttc cggtacgcta caggcgtgga tgaccgtcga gaatatcgat cttaaaacga
    15181 ttggcttctt ctcgctggtt ggtcaggcct atgtgtttaa gtttctctgg tctccgctga
    15241 tggaccgcta cacgccgcct tttttaggtc gacgtcgcgg ttggttactc gccacccaac
    15301 tgttgttact ggcggcgatt gcggcgatgg gctttcttga acccggcacg cagctacgct
    15361 ggatggcggc gctggcggtg gtgattgctt tttgctccgc ctcgcaggat atcgtgttcg
    15421 acgcctggaa aaccgatgtg ttacccgcag aagaacgcgg cgctggcgcg gcaatcagcg
    15481 tgcttggcta ccggttgggg atgctggttt ccggcggact ggcgctatgg ctggccgatc
    15541 gctggctcgg ctggcagggc atgtactggc tgatggcggc attgttgatc ccctgcatta
    15601 tcgccacctt actggcgccg gaaccgaccg atactatccc ctccccgaaa tcgctggaac
    15661 aggccgtcgt cgcgccgcta cgcgatttct ttggccgtaa caacgcctgg ctgattttac
    15721 tgctcattgt gctttataaa ctgggtgacg ccttcgccat gagcctgacc accacctttt
    15781 tgattcgcgg cgtcggcttt gacgccggcg aagtcggtgt ggtcaataaa acgttgggcc
    15841 tgctggcgac gatcgtcggc gcgttatacg gcggcatatt aatgcagcgt ctttcgctgt
    15901 ttcgcgcgct gctgattttc ggcattttgc aaggcgcgtc caacgccggt tactggttgc
    15961 tctccattac cgataaaaac atgttcagca tgggcgcggc ggtctttttc gaaaatctgt
    16021 gcggcgggat gggtactgcc gcctttgtcg ccttattaat gacgctatgt aataagtcgt
    16081 tttccgcaac acagtttgcc ctactgtcgg ccctctccgc agtaggccgg gtttatgttg
    16141 gtcctgtagc gggctggttc gttgaagcgc acggctggcc gacattctac ctcttctcgg
    16201 ttgtcgccgc cgttcccggg ctgttactgt tgctggtctg tcggcaaacg ctggaatata
    16261 gctggcagag cgagcgtttc attccccgca cgcaataccg tggcacctac aatttcgcgc
    16321 tttcaatcct gctcgcgggc gtcgctttgc tggcggtgtg ggtactcctg ctgaccatga
    16381 acgcgttgga ttacactaac ttttcattcc tgcccgaatt gcttgagact gcggtagcga
    16441 ttgccgtgtg cggcattgtc tttggcgggt tgctggacta cctggcgcta cgaaaaacac
    16501 gcctgctgta aaacattatt tgccgttgta ataacgaccc ggaattataa cgg
//
LOCUS       DAJVKX010000096        16380 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.096, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000096 DAJVKX010000000
VERSION     DAJVKX010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16380
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.096"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            31..870
                     /locus_tag="OPY25_003164"
     CDS             31..870
                     /locus_tag="OPY25_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HCS0928715.1"
                     /translation="MAANGENNPSNLLGAPVNTAISGGSVLPEGKLLTAVNSSFRDKD
                     HQIEGHGSPDVYSQIWLLKIRYGLTDRLELSTVGSYINNKRDNLSPEHIEGMSDQSVG
                     VNYALMSQRRGDPFWVTVGGAVLLPTGQDGDNHLPGNSAWGGRVTLTLTKLFTPNIKG
                     DMGFVYQGPFERGNQDVKRGNEFQWNTQVRYMFSDLPLDLGLESAYSNNASGTKKLSN
                     GSVINNHSGTTEWVVGPSFNIAVDSLKLWFGAGAFFPVMQEAKSPTKMEDVRWEFKIG
                     KTW"
     gene            complement(918..2351)
                     /gene="bglA"
                     /locus_tag="OPY25_003165"
     CDS             complement(918..2351)
                     /gene="bglA"
                     /locus_tag="OPY25_003165"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HCS0928716.1"
                     /translation="MRKLTLPKDFLWGGAVAAHQVEGGWNKDGKGPSICDVLTSGAHG
                     VPREITQNVVAGKYYPNHEAVDFYGHYKEDIRLFAEMGFKCFRTSIAWTRIFPNGDES
                     QPNEAGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQHYGGWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASTLAVKAARRINPQMKVGCMLAMVALYPFSCKPEDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLEVLREGTCDYLGFSYYMTNAVKAEGGSGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYSLCELYERYQKPLFIVENGFGAYDKVEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGLIYVNKHDD
                     GTGDMSRSRKKSFNWYKEVIASNGEKL"
     gene            2510..2821
                     /locus_tag="OPY25_003166"
     CDS             2510..2821
                     /locus_tag="OPY25_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCS0928717.1"
                     /translation="MQPNDITFFQRFQNDILAGRKTITIRDASESHFKAGDALRVGRF
                     EDDGYFCTIEVTGTSTVTLDTLNEKHAQQENMSLDELKRVIAEIYPNQTQFYVIDFKC
                     L"
     gene            2985..3644
                     /locus_tag="OPY25_003167"
     CDS             2985..3644
                     /locus_tag="OPY25_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCS0928718.1"
                     /translation="MVQKPLMTQGYSLAEEIANSISHGIGLVFGIVGLVLLLVQAVEA
                     NAGMTAIASYSLYGGSMILLFLASTLYHAIPHQRAKIWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALFGILFKLTIAHRFKVLSLVTYLAMGWLSLIVVYQLA
                     IKLAIGGVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYVGQ
                     A"
     gene            complement(3760..4740)
                     /gene="ygfZ"
                     /locus_tag="OPY25_003168"
     CDS             complement(3760..4740)
                     /gene="ygfZ"
                     /locus_tag="OPY25_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HCS0928719.1"
                     /translation="MAFISFPPRHPSSSARLPLTLIALDDWALSSITGVDSEKYIQGQ
                     VTADVSQMTEQQHLLAAHCDAKGKMWSTLRLFRERDGFAWIERRSVREAQLTELKKYA
                     VFSKVVIAPDDERVLLGVAGFQARAALANVFSELPNSENQVVRDGASTLLWFEHPAER
                     FLLVTDVATANMLTEKLHGEAELNNSQQWLALDIEAGIPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGKASRVPEAGEDLELQMGENWRRT
                     GAILAATQLDDGQLLVQAVMNNDLEAESVFRVRDDANTLHIVPLPYSLEE"
     gene            4990..5256
                     /gene="sdhE"
                     /locus_tag="OPY25_003169"
     CDS             4990..5256
                     /gene="sdhE"
                     /locus_tag="OPY25_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HCS0928720.1"
                     /translation="MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFV
                     RLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRNRERGPVAI"
     gene            5237..5638
                     /locus_tag="OPY25_003170"
     CDS             5237..5638
                     /locus_tag="OPY25_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HCS0928721.1"
                     /translation="MVLWQSDLRVSWRAQWISLLLHGLVAAVILLMPWPLSYTPLWMI
                     LLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQDWTLLRPPWLLKSGMVLRLRAE
                     SGRHQHLWLAADSMEEAEWRELRRILLQQPI"
     gene            complement(5703..6224)
                     /gene="fldB"
                     /locus_tag="OPY25_003171"
     CDS             complement(5703..6224)
                     /gene="fldB"
                     /locus_tag="OPY25_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HCS0928722.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDILGPELVTLHNLKDDAPALME
                     QYDVLILGIPTWDFGEIQEDWEAVWEQLDDLNLEGKIVALYGMGDQLGYGEWFLDALG
                     MLHDKLALKGVKFVGYWPTEGYEFTSNKPVIADGQLFVGLALDETNQYDLSDERIQTW
                     CEQILGEMAEHYA"
     gene            6337..7233
                     /gene="xerD"
                     /locus_tag="OPY25_003172"
     CDS             6337..7233
                     /gene="xerD"
                     /locus_tag="OPY25_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCS0928723.1"
                     /translation="MEQDLARIEQFLDALWLERNLAENTLSAYRRDLSMVVAWLHHRG
                     KTLATAQADDLQTLLAERVEGGYKATSSARLLSAMRRFFQHLYREKYREDDPSAQLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            7257..7970
                     /gene="dsbC"
                     /locus_tag="OPY25_003173"
     CDS             7257..7970
                     /gene="dsbC"
                     /locus_tag="OPY25_003173"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HCS0928724.1"
                     /translation="MKKRFMMFTLLAAAFSGVAHADDAAIRQSLAKLGVQSTEIQASP
                     VAGMKTVLTHSGVLYVTDDGKHIIQGPMYDVSGAHPVNVTNKLLMSQLNALEKEMIVY
                     KAPDEKHVITVFTDITCGYCHKLHEEMKDYNALGITVRYLAFPRQGLESQAEQDMKSI
                     WCAKDKNKAFDDAMAGKGVKPASCDVNIADHYALGVQLGVSGTPAIVLSNGYVVPGYQ
                     GPKEMKAFLDEHQKQTSGK"
     gene            7976..9709
                     /gene="recJ"
                     /locus_tag="OPY25_003174"
     CDS             7976..9709
                     /gene="recJ"
                     /locus_tag="OPY25_003174"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCS0928725.1"
                     /translation="MKQQRQLRRREADETAELPADLPPLLRRLYASRGVRSARELERS
                     VKGMLPWQQLSGIDNAVEILYNAFREGTRIIVVGDFDADGATSTALSVLGMRALGCDN
                     ISYLVPNRFEDGYGLSPEVVDQAKARGAQLIVTVDNGISSHAGVAHAKTLRIPVIVTD
                     HHLPGDTLPDAEAIINPNLRDCEFPSKSLAGVGVAFYLMLALRTFLRDKGWFDERGIA
                     PPNLAELLDLVALGTVADVVPLDANNRILTWQGLSRIRAGKCRPGIKALLEISNRDPQ
                     QLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNLGEARVLASELDALNQTRKEIEQ
                     GMQAEALILCEKLERSSETLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPDLMIKFGGHAMAAGLSLEEHKFEQFQQRFG
                     ELVTEWLDPALLQGEVISDGPLSAAEMSMEVAQLLRDAGPWGQMFPEPLFDGRFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNIDTTCWPDNGVREVELAYKLDINEFRGNRS
                     LQIIIDDIWPL"
     gene            9814..10912
                     /gene="prfB"
                     /locus_tag="OPY25_003175"
     CDS             join(9814..9888,9890..10912)
                     /gene="prfB"
                     /locus_tag="OPY25_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCS0928726.1"
                     /translation="MFEINPVNNRIQDLTERTNVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAIVDTLDQMTQGLDDVSGLLELAVEADDEETFNEAVAE
                     LNTLEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLLRMYLRWAEARG
                     FKTEVIEESEGEVAGIKSATIKISGEYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIDINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDTKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            10922..12439
                     /gene="lysS"
                     /locus_tag="OPY25_003176"
     CDS             10922..12439
                     /gene="lysS"
                     /locus_tag="OPY25_003176"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCS0928727.1"
                     /translation="MSEQNAQGADEVVDLNNEMKARREKLAALREQGIPFPNDFRRDR
                     TSDQLHAEFDAKEAEELEALNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKTRSKILAGIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDVLGTTQVPYGDEVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVNAKAAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(12515..13060)
                     /gene="idi"
                     /locus_tag="OPY25_003177"
     CDS             complement(12515..13060)
                     /gene="idi"
                     /locus_tag="OPY25_003177"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCS0928728.1"
                     /translation="MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDG
                     QLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHF
                     SYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWQSLLATPWAFSP
                     WMVMQASDEQARKRLLNYCQR"
     gene            13325..14083
                     /locus_tag="OPY25_003178"
     CDS             13325..14083
                     /locus_tag="OPY25_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCS0928729.1"
                     /translation="MVLSAGRLNKNSLGIAVLLCTGLLLAGCSSNSGSGTYSGSVYTV
                     KRGDTLYRISRATGTSVKELARLNGISPPYTIEVGQRIKVRGSAKSSSSTRKTSNKTA
                     TKTAAVRPSSSVPKSSWPPVGQRCWVWPANGKVILPYSTAEGGNKGIDIAGARGTPVY
                     AAGAGKVVYVGNQLRGYGNLIMIKHNEDYITAYAHNDTMLVNNGQSVKAGQKIATMGS
                     TDAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            14163..14236
                     /locus_tag="OPY25_003179"
     tRNA            14163..14236
                     /locus_tag="OPY25_003179"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14195..14197,aa:Gly,seq:ccc)
     gene            14371..15990
                     /locus_tag="OPY25_003180"
     CDS             14371..15990
                     /locus_tag="OPY25_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCS0928730.1"
                     /translation="MLNSKTYLYQRNGVFYIRLRMKSTDRLTVSHPSHSRYKIASVSL
                     RTKDRRTAMAYSRHIKAALRAIHADRPNASYEEMREHLRDIAEWELSTGRSDLFEPDM
                     RDLYRDQYGEVGENLVHSEPLTIDQHRYINEALNVLKACMKRIEAGDSQPLIDYIDGF
                     DAAAGANDQASATLSVSAPQKTSITEGKHCVTVASLFEQYEQENAQNWKPATLRENKA
                     SHAALIEVFDYLGLNADANVLARADMLRVRDILQQLPKNRKQRFKDVPLVDLLGREDK
                     TDCLDIVTINNKYLIKMAAVFKWAVRNDLIKKNMTEGLELKVPQRKASEARNAFSTEQ
                     VGQLLAAAQVYSQRPSGKPYHYYVTALAAITGARLNEIAQLQVKDVRTTEAGTVYIHI
                     NEDDSSLPGKSIKNAHSDRCVPLVDGAYGFILADFMRLVETRRGADGDDAMVFDGLRL
                     MKNGYGEQVSKWFNRTLLPKVLADRSGLAFHSFRHTVATQLKQHGVELAYAQAIMGHS
                     SGSITYDRYAKEVEVDRLVNVMADVYKEIVG"
BASE COUNT         3995 a         3948 c         4451 g         3986 t
ORIGIN      
        1 ttaatgacat attttctatt aatgaatgca atggcagcta acggagaaaa taatcccagt
       61 aatctattag gtgcaccagt taataccgct atttctggtg gttcagtatt gccggaagga
      121 aagttattaa ccgccgtgaa tagctcattt cgcgataaag atcatcaaat cgaggggcac
      181 ggaagtccgg atgtttactc ccagatatgg ttattgaaga ttcgttacgg tttgaccgac
      241 agactggaat tatcaactgt gggttcctat atcaataaca aacgagacaa tctgtctcct
      301 gagcacatag agggaatgag cgaccaatcg gtgggggtca attatgcttt aatgagccag
      361 cgaagaggtg atccgttttg ggttacggta ggtggggcag tattactacc caccgggcaa
      421 gatggagata atcatttgcc tgggaatagc gcctggggag gaagagtaac actcacttta
      481 acaaaattat ttactcctaa cattaaaggg gatatgggtt ttgtatatca gggaccattt
      541 gagcgcggta accaggacgt gaaacgaggt aacgaattcc agtggaatac ccaggtgcgg
      601 tatatgttta gcgatttacc gctggatctt ggtctggaaa gtgcctacag caataatgcc
      661 tctggaacga aaaaactgtc taatggcagc gtaattaata accattctgg aactaccgaa
      721 tgggttgttg gtccgtcatt taatattgcc gtcgattcac tgaaattatg gtttggtgcc
      781 ggagccttct tcccggtaat gcaggaagcg aagtcgccaa ccaaaatgga agatgtacgc
      841 tgggaattta aaataggtaa gacctggtaa gactcgttca aagtgttacc cgccgactgg
      901 cgggtaacgt gcaggagtta aagcttctcg ccgttgctgg caatcacctc tttgtaccag
      961 ttgaagctct tcttacgcga acgcgacata tcgcccgtac cgtcatcgtg cttgttcacg
     1021 tagattaagc cgtagcgctt gctgtactga ccggtggtga acgacacgca gtcgatgcag
     1081 ccccacggcg tgtagcccat caggtcgaca ccatcgtaag tcaccgcttt tttcatctct
     1141 tcaatatggg cgcgcaggta gtcaatgcga tagtcgtcgt tgatgctgcc atcttcttct
     1201 actttgtcgt aagcaccaaa accgttttcg acaataaata gcggcttttg atagcgttcg
     1261 tacagttcac acaatgaata gcgcagaccc accgggtcaa tctgccagcc ccagtcagat
     1321 gctttaacat aggggttcgg tacgctgcct tcaaaaccgg aaatcgcatc gccgctaccg
     1381 ccttcggctt tgaccgcgtt ggtcatgtaa taactgaaac caagataatc gcaggtgcct
     1441 tcgcgcagca cttcaagatc gccatcttcc attttgatgt taaatccgcg gcgctcccac
     1501 tcgttcaaca cataggacgg gtaatagccg cgcagctgca catcggtaaa gacgtagcgt
     1561 tcacgcatcg attcctgagc aaacatcaca tcttctggtt tacaggagaa aggatacagc
     1621 gcgaccatcg ccagcataca gccaactttc atctgtggat taatacgacg tgccgctttt
     1681 accgccagcg tgctggcgac aaactgatga tgtaagacct gatacatggt ttcttctgga
     1741 ttctcatgct cggtatacac cacgccggaa cagcagtagc caaacagcgg cgcgcgccag
     1801 tttcgctggt tgttaatttc gttgaaggtc atccagtatt tgaccttatg tttgtagcgt
     1861 tcaaacacga cttcagcaaa acggacaaag aaatcaacca ctttacgatt ggtccagccg
     1921 ccgtagtgct gtaccagatg taatggcatt tcaaagtgag aaagggtgat gaccggttcg
     1981 atgttgtatt tgagtaactc atcaaacatg tcgtcgtaga atttcagacc ggcctcgttt
     2041 ggctgggatt cgtcgccatt cgggaagata cgcgtccagg caatagaagt acggaagcat
     2101 ttgaacccca tttcggcgaa aagacggatg tcttctttgt aatgtccgta aaaatccacc
     2161 gcctcgtggt tcggatagta tttgccagca acgacattct gggtgatttc gcgtggcacg
     2221 ccgtgtgcgc cgctggttag cacgtcgcag atgctggggc ctttaccgtc tttattccag
     2281 ccgccttcaa cctggtgtgc ggcaaccgcg ccgccccata aaaaatcttt tggcagggtg
     2341 agttttctca ttgttgcata atctcaattt atttagtctg ttatcattca ttctgcacca
     2401 agtggcatgt aaagcgtacg caaaattcca ggatgctcgc gtgtcggggc aagaacacat
     2461 tcagatcgta acatccactt caaggggcca tattcagggg gataaccaca tgcagccaaa
     2521 tgacattact ttctttcaac gtttccagaa tgacattctg gcagggcgta aaaccatcac
     2581 tattcgtgat gcctccgagt cccactttaa agcaggcgat gctctacgcg tggggcggtt
     2641 cgaagatgat ggctattttt gcacaatcga agtgacagga acgtcaactg tgacgctgga
     2701 tacgttgaac gaaaaacatg cgcaacagga aaatatgtcg cttgatgagc tgaaacgggt
     2761 cattgctgaa atctatccca accagacgca attttatgtg attgatttta aatgcctttg
     2821 ataaatatga acgcgtgtta gttgagtttt tgtagttaat ttgttgaata ataaacaaaa
     2881 tttaattttg cgaatttatt ttagctaaca tgtgttcact ggaaccattc tcagttacgc
     2941 tagaggtgca gttcatcgtt atgaacgttt ctccggagta agttatggtg caaaaaccat
     3001 taatgacgca gggatattcg ctggctgagg aaatcgccaa cagtattagc cacggcattg
     3061 gattggtatt tggtattgtc ggcctggtgc tgttgttggt tcaggcggta gaggcgaatg
     3121 cgggtatgac ggctatcgcc agctacagtt tatatggcgg gagcatgatc ctgctttttc
     3181 ttgcctcaac gctttatcat gccattcctc atcagcgggc aaaaatctgg ttaaagaaat
     3241 ttgatcactg cgctatctat ctgctcattg ccggaaccta tacgccattt ctgctggtag
     3301 gtctggattc gccgctggcg cgcggactaa tgattgtgat ctggagcctg gcgctattcg
     3361 gtatcctctt caagttgacg attgcgcacc gatttaaagt gctttcactg gttacgtatc
     3421 tggcaatggg ctggctgtcg ctgatagtgg tttatcagtt ggcgattaag ctggcgatag
     3481 gcggcgtgac gctgctggcg gtaggtggcg tcgtttactc gctgggcgta attttctatg
     3541 tttgcaaacg cataccttat aaccacgcca tctggcatgg ctttgtgctg ggcggcagcg
     3601 tgtgccactt cctggccatc tatttgtatg tgggacaggc gtaattcccg gatgcccgtg
     3661 ccggatggcg gcgctgtcgt accttatccg gcctacgaga gcagcacgtg cgagcctgat
     3721 ggcgttgcgc tatcaggcta tccgactttt aacgtgatat cactcttcca acgagtaagg
     3781 cagcgggacg atatgcaggg tgttggcatc gtcgcgaacg cggaagacgc tttcggcttc
     3841 taaatcgtta ttcatgacgg cctgaaccag taactgacca tcgtccaact gtgtcgccgc
     3901 cagaatagcg ccggtacgac gccagttctc gcccatctgt agctccagat cttctcctgc
     3961 ttccggtacc cggctggctt tgcccgccag caaccaaagc gcgcgtttat tggcgccgcg
     4021 gaattttgcc cgtgcgacca tctcctgtcc ggtgtagcag cctttcttga agctgatgcc
     4081 gcccagcgcc tgtaggttag tcgcctgggg gataaactga ccgctgttcg ccgcgtcaat
     4141 caccggaatg cctgcttcaa tatccaacgc cagccactgt tgactgttat tcagttcggc
     4201 ttcgccatgc aacttctccg ttaacatgtt ggccgtcgcg acatcggtga caagcaggaa
     4261 tcgttccgca ggatgttcaa accatagcag cgtggaggcg ccgtctctga ccacctgatt
     4321 ttcactattg ggcagttcgc taaagacatt agccagcgcc gcgcgggcct gaaaaccggc
     4381 cacgccaagc aatacgcgtt cgtcatccgg cgcgatgact actttggaaa atacggcgta
     4441 ctttttcagc tccgttaatt gcgcttcacg cacgctacgg cgttcaatcc aggcgaaacc
     4501 gtcgcgctca cggaacagtc gcagagtgct ccacatctta cctttagcat cgcagtgggc
     4561 ggcgagaagg tgttgctgtt cagtcatctg gcttacgtca gcggtgacct ggccctgaat
     4621 atacttttca ctgtctacgc cggtaatgga cgacagcgcc cagtcgtcaa gcgcgatcag
     4681 cgtcagcggc aggcgggctg acgatgaggg atgacgtggt ggaaaggaga taaaagccat
     4741 aaataatgtc ctggttagct gcaacaataa tggttaatgg taaaagagcc atcggtcatt
     4801 gcaagtgctt taaatagccc attgaaagcg gattgatcgt tttgcgaggt ggtatccaaa
     4861 acggatgaac atattgattc ccagccttct atttcgcgat cgcgttccag attactgaga
     4921 ttcccgtaaa acaacgccaa aaacacgtta caatagcccg gtacttcatt ttcgcgaggc
     4981 aggaagaaca tggatattca caataaagca cgtattcact gggcatgtcg tcgcggtatg
     5041 cgcgaacttg atatttccat catgccgttt tttgaacatg agtacgatag tttaagtgat
     5101 gaagaaaagc gtatttttgt ccgtttgttg cagagtgatg acccggattt atttaactgg
     5161 ttaatgaatc acggtaaacc ggctgacgct gaactggaac agatggtccg actcattcag
     5221 acacggaatc gggaacgtgg tcctgtggca atctgattta cgcgtctcat ggcgcgctca
     5281 gtggatctca ttgctccttc atgggctggt tgccgcggtg attttattga tgccctggcc
     5341 gctgagttat accccgttat ggatgatact actgtcgctg gtcgtgtttg actgtgtacg
     5401 tagccagcgc aggattaata cctgccaggg agagatcaag ctactcatgg acgggcgctt
     5461 acgctggcag ggacaggact ggacgctctt gcgtcctccc tggttactga agagcgggat
     5521 ggtgttgcgt ttacgcgcag agtctggacg tcatcagcat ttatggctgg cggcggatag
     5581 catggaagaa gcggaatggc gtgagttgcg tcggatactg ttacagcagc cgatatagcg
     5641 ccaacactga cggaacgacg caaacgcggt tccgtcgaga gggaaataca gcgagtaagg
     5701 cttcaggcgt agtgttcggc catttcgccg agaatttgtt cacaccaggt ctgtatacgc
     5761 tcatcgctga gatcgtactg gttcgtttca tccagcgcca ggccgacaaa cagttgccca
     5821 tccgcaatga ccggtttatt gctggtaaat tcgtagcctt ctgtgggcca gtagccgaca
     5881 aatttaacgc ctttgagggc aagtttgtca tgcaacatac ccagcgcatc caggaaccac
     5941 tcgccgtagc cgagttggtc gcccataccg taaagcgcaa cgattttgcc ttccagattg
     6001 agatcgtcca gttgctccca gacggcttcc cagtcctcct gaatttcgcc aaaatcccag
     6061 gtggggatgc ctaaaatgag cacgtcgtac tgctccatta aggcgggggc gtcatccttg
     6121 aggttatgta atgtcaccag ctccgggccg aggatatcgc gaattttctc tgcggccatc
     6181 tcggtgtagc acgtgctgga accgtaaaaa agacccatgt tcattacgtt acatctcgat
     6241 tctgctatag cgttgcgggt agtgtaacag aatcgctgca ttcacggcac aatgaggcat
     6301 aatgcaccaa aagtaagcgt gaagtaggga gcgcgaatgg aacaggattt agcgcgtatt
     6361 gagcagtttc tggatgccct gtggctggaa cgaaatctgg cggaaaatac attaagcgcg
     6421 tatcgtcgcg atttatcgat ggtcgttgcg tggttgcatc atcgcggaaa aacgcttgcg
     6481 acggcgcagg ctgatgattt acaaacgcta ttggctgaac gggtggaggg cggatacaaa
     6541 gcgaccagct ccgcacgcct gttaagcgct atgcggcgct ttttccagca tctgtaccgt
     6601 gaaaagtatc gtgaggatga tccgagcgca cagttggcct cgcctaagct tccgcagcgt
     6661 ttaccgaaag accttagcga ggcgcaggtt gaacggctct tgcaggcgcc gcttattgat
     6721 caacctttgg agttgcgcga taaagctatg ttggaagtgc tgtatgccac cggtttgcgc
     6781 gtgtcggaac tggtggggct gacaatgagc gatatcagtc tgcggcaggg cgtggtgcgg
     6841 gttatcggta aaggcaataa agagcggttg gtgccgttag gcgaagaggc ggtatattgg
     6901 ctggaaacgt atctggagca tgggcgtccc tggttactca atggcgtatc gattgacgta
     6961 ttattcccca gtcagcgtgc gcagcagatg acgcgacaga ccttctggca ccgtattaaa
     7021 cattatgcgg tactggctgg aattgatagc gaaaaactat cgccgcatgt tttacgtcac
     7081 gctttcgcca cgcatttgct gaatcacggc gccgacttgc gcgttgtaca aatgctactt
     7141 gggcatagcg atctttcgac gacacaaatt tatacgcatg tcgcaacgga gcgtttgcgt
     7201 caacttcatc aacagcacca tccgcgggca tgagtgctga caggaaagga tagtttatga
     7261 aaaagcgttt tatgatgttc actttactgg cggcggcgtt ttcaggcgtg gcccatgcgg
     7321 atgatgcggc tatccgtcag tcgctggcta agctgggcgt tcagagtacg gaaattcagg
     7381 cctcgccagt ggcagggatg aaaaccgtcc tcactcacag cggcgtactg tacgtcactg
     7441 acgacggcaa acatattatt caagggccga tgtatgacgt gagcggcgcg catccggtaa
     7501 atgtgacgaa caaactgctg atgagccagc taaatgcgct ggaaaaagag atgatcgtct
     7561 ataaagcgcc ggatgagaaa catgtcatta ctgtttttac cgatatcacc tgcggctatt
     7621 gtcataagct acatgaagag atgaaagatt ataacgcgct ggggatcacg gtacgttatc
     7681 tggcttttcc gcgccagggg ctggaaagcc aggcggagca ggatatgaaa tctatctggt
     7741 gcgccaaaga caaaaacaaa gcgtttgatg acgccatggc aggtaagggc gtgaaaccgg
     7801 caagctgtga cgtgaacatt gctgatcatt atgcgttggg cgtgcagttg ggcgttagcg
     7861 gtacgccagc cattgtattg agtaacggct atgtggtgcc tggctatcag ggaccgaaag
     7921 agatgaaagc gtttcttgat gagcatcaaa aacagaccag tggtaaataa tacgcgtgaa
     7981 acaacagaga caacttcgtc ggcgcgaggc tgatgagacg gcggaactcc ccgccgatct
     8041 tcctccatta ctacgacgtc tatatgccag ccggggcgtt cgtagcgccc gcgaactgga
     8101 gcgcagcgtg aaaggaatgc tgccctggca acagcttagc ggcatagata acgcggtgga
     8161 gatcctctac aacgcctttc gcgaaggtac ccgcattatt gttgttggcg attttgacgc
     8221 cgacggcgcg accagtactg cgctaagcgt attgggaatg cgtgcgttgg gatgtgacaa
     8281 catcagttat ctggtgccta atcgctttga ggacggctac ggtttaagcc cggaagtggt
     8341 cgatcaggcg aaggcgcgcg gcgcacagct tatcgtcacc gtagacaacg gcatttcatc
     8401 ccacgctggc gtagcgcatg caaagacgtt gaggattccg gtgatcgtga ccgatcacca
     8461 cctgcctggc gacacgttgc cggatgccga agcgattatt aatcccaatc tgcgcgactg
     8521 cgaattcccg tctaagtcgc tggcgggcgt cggcgtggcg ttttacctga tgctggcgtt
     8581 gcgaacattt ttgcgcgaca aaggatggtt cgacgagcgc ggcatcgcgc cgccgaatct
     8641 ggcggagctg ctggatttag tggcgttggg aacggtagca gacgttgtgc cgctggacgc
     8701 caacaaccgt attctgacct ggcaagggct aagtcgtatt cgtgccggga aatgccgtcc
     8761 gggaattaaa gcgttgctgg agatatcgaa tcgcgatccg cagcagcttg ccgccagtga
     8821 tttaggcttc gcgttggggc ctcgtctgaa tgccgccggc aggctggatg atatgtccgt
     8881 tggcgtggcg ttactgttgt gcgacaacct cggcgaagcg cgtgttctgg ccagcgagct
     8941 ggatgcgctt aaccagacgc gcaaagaaat agagcagggg atgcaggcgg aagcgcttat
     9001 cctgtgcgaa aagcttgagc gcagtagtga aacgcttccg ggcggtctgg cgatgtatca
     9061 tcctgaatgg catcagggcg tggtcggaat tctggcgtcg cgcattaaag agcgttttca
     9121 ccgcccggtg atcgcctttg cacctgcggg cgacggcacg ctaaaaggct caggccgttc
     9181 gattcagggg ttgcatatgc gcgatgcgct ggaaaggctg gatacgcttt accctgatct
     9241 gatgatcaag ttcggcggtc atgcgatggc ggcgggattg tcgctggaag agcataaatt
     9301 cgagcagttt cagcaacgtt ttggcgagct ggtgacggaa tggctcgatc ctgccctgtt
     9361 gcaaggcgag gtgatctccg atggtccatt aagcgcggcg gagatgtcta tggaagtggc
     9421 gcaactgttg cgggatgccg gaccgtgggg gcaaatgttc ccggaaccgt tattcgatgg
     9481 tcgtttccgt ctgctacaac agcgtctggt gggcgagcgc cacctcaagg tgatggtgga
     9541 gcctgtcggc ggcggcccgc tgttggatgg catcgcattt aatattgata cgacctgttg
     9601 gccggataac ggcgtgcggg aggtagaact ggcttataaa ctggacatta acgagtttcg
     9661 cggcaaccgt agtttacaga ttattatcga tgatatttgg ccgctatgat cggggcgatt
     9721 taacaacact ttcgctgtaa ttaaggggcg aaatccgcta atatttcacc cttataaccg
     9781 cattttgaca agtcaaataa aagaaatcag accatgtttg aaattaaccc ggtgaataac
     9841 cgcattcagg acctcacgga acgcaccaac gttcttaggg ggtatctttg actacgatgc
     9901 taagaaagag cgtctggaag aagtaaacgc cgagctggaa cagccggatg tctggaacga
     9961 acctgagcgc gcgcaggcgc tgggaaaaga acgttcatcg ctcgaagcga ttgtcgatac
    10021 gcttgatcaa atgactcagg ggctggacga cgtttccggg ctgctggaac tagcggtaga
    10081 agctgacgac gaagagacgt ttaacgaagc cgtcgcggaa ctgaatacgc tggaagagaa
    10141 gctggcgcag ttggaattcc gccggatgtt ctccggcgag tacgatagcg ccgattgcta
    10201 tctcgatatt caggccggtt ccggtggtac tgaagcacag gactgggcca gcatgttgct
    10261 gcgtatgtat ctgcgttggg cggaagcgcg cggcttcaag acggaagtca ttgaagagtc
    10321 ggaaggggaa gtcgccggca ttaagtccgc gactatcaaa atctccggcg aatatgccta
    10381 tggctggctg cgcactgaaa ccggcgtaca tcgtctggtg cgtaaaagcc cgttcgactc
    10441 cggcggtcgc cgtcatacct cgtttagctc cgcgtttgtg tatccggaag tggacgacga
    10501 tatcgatatc gacattaacc cggcggatct gcgtatcgac gtctatcgcg cgtctggcgc
    10561 aggcggtcag cacgttaacc gtacggaatc cgcagtgcgt atcacccata ttcccaccgg
    10621 gatcgtgacg cagtgccaga acgaccgttc gcagcacaaa aacaaagacc aggccatgaa
    10681 gcagatgaaa gcgaagcttt atgaactgga gatgcagaaa aagaacgctg aaaaacaggc
    10741 gatggaagac actaagtctg atatcggctg gggaagccag attcgttcct atgtcctgga
    10801 cgattcccgc attaaagacc tgcgtactgg ggtggaaacc cgcaatacac aggcggtact
    10861 ggacggtagt ctggatcaat ttatcgaagc aagtttgaaa gcagggctat gaggaatcaa
    10921 catgtctgaa caaaacgcac agggcgctga cgaggtagtc gatcttaaca atgaaatgaa
    10981 ggcacgtcgc gagaagctgg ctgcactgcg tgagcagggt atcccgttcc cgaacgattt
    11041 ccgtcgtgac cgtacctcag accaactgca cgcagagttt gacgcgaaag aagctgaaga
    11101 actggaagcg ctgaatattg aagtgtccgt cgcgggccgt atgatgactc gccgtattat
    11161 gggtaaagcc tcttttgtta ccctgcaaga cgtaggcggc cgcattcagc tgtatgtggc
    11221 gcgcgatgat ctgccggaag gcgtttacaa cgagcagttc aagaagtggg atcttggcga
    11281 tatcctcggc gcgaaaggta agctgttcaa aaccaaaacc ggcgagctgt ctatccactg
    11341 caccgaactg cgcctgctga cgaaagcgct gcgtccgttg ccggataaat tccacggcct
    11401 gcaggaccag gaagcgcgct atcgccagcg ttatctggat ctcatctcta acgatgaatc
    11461 ccgtaatacc ttcaaaaccc gttcgaagat cctggccggt attcgccagt ttatggttgc
    11521 tcgcggcttt atggaagtcg aaacgccgat gatgcaggtg atcccaggcg gcgcgtctgc
    11581 ccgtccgttt atcacccatc acaacgcgct ggatctggac atgtacctgc gtatcgcgcc
    11641 agaactgtac ctgaagcgtc tggtggttgg cggcttcgaa cgcgtattcg aaattaaccg
    11701 taacttccgt aacgaaggca tctccgtgcg ccataatcct gagttcacca tgatggaact
    11761 ctatatggcg tatgcggact acaaagacct gatcgagctg actgagtctc tgttccgtac
    11821 gctggcgcag gatgttctgg gcaccaccca ggttccatac ggtgatgaag tgtttgactt
    11881 cggtaagccg ttcgaaaaac tgaccatgcg tgaagcgatc aagaaatatc gtccggaaac
    11941 ggatatggct gatctggaca acttcgactc cgcgaaggcg attgctgaaa gcatcggcat
    12001 tcacgtcgag aagagctggg gtctgggccg tatcgtcacc gagatctttg acgaagtcgc
    12061 tgaagcgcat ctgattcagc cgaccttcat caccgaatat ccggctgaag tgtctccgct
    12121 ggcgcgtcgt aatgatgtga acccggaaat cactgaccgc ttcgagttct ttatcggcgg
    12181 tcgtgaaatc ggcaatggct ttagcgagtt gaacgatgcg gaagaccagg cgcagcgttt
    12241 cctggatcag gttaatgcaa aagcggcggg cgacgacgaa gccatgttct acgacgaaga
    12301 ctacgtgacg gcgctggaac acggtttacc gccgacagcg ggtctgggaa ttggtatcga
    12361 ccgtatggtg atgctgttta ctaacagcca cacgattcgc gacgttattc tgttcccggc
    12421 gatgcgtccg gtgaaataag atgtaaattg ccggatgggg cattagccgc catccggcat
    12481 ctcttcgttc agacgtagcg ccatcaggca atctttaacg ctggcagtaa ttgagcagtc
    12541 gtttacgcgc ttgttcgtct gacgcttgca tgaccatcca cgggctaaat gcccacggcg
    12601 tagcgagaag gctttgccat acgcttttaa attcgctcca ctgatagtcc atcacctctt
    12661 cgctgttaac ctgtaacaca ctggttgccc gcgcggcaaa taccggacag acttcatttt
    12721 ccacaatacc gtttggatct gtcgcccgat agctgaagtg cggatagacg ggggtgagat
    12781 cggtaatttc cacgccgagt tcgaaccgac aacggcggat gatcgcctct tcggtggttt
    12841 cgccttgttg cggatgaccg caaaccgaat tcgtccacac gcctggccag gctttcttgc
    12901 tcagcgaccg tcgtgttacc agcaattggc catcttcgtt aaatagccag caggagaaag
    12961 ccagatgcaa aggcgtatta agcgtatgag ccgcatactt ttccagtgtg ccggaaggct
    13021 tatcctgctc atccaataaa acgacatgtt cctcagtcat gaaagctcct gaaaattaaa
    13081 atgacccggc agcatggcca ggccatatac tcagacgatc agcgtagcgc ataacagaaa
    13141 gaaaggcatt accaaaacag gccctgacag aacgcagacg agcgctattg tgccgtgatt
    13201 cgatattatg ctggcatatc ggatattcgc ggcatcatca tccacacgga ccctttccgg
    13261 cgtcaatgga ttgggcatac ggcatttggc tgctatcata aggcgtctgt caatagagtg
    13321 aggaatggtt ttgagcgcag gacgcctgaa caaaaatagc ctgggtattg cggtgctgtt
    13381 atgcacaggg ctgctgctgg cggggtgttc cagtaattcc ggctcaggaa cgtattccgg
    13441 ctccgtctat accgttaagc gcggcgatac gttgtatcgt atatcgcgcg ctacgggaac
    13501 cagcgtgaaa gaactggccc gactgaatgg catttctccg ccttatacta ttgaggtggg
    13561 gcagcgaatt aaagtgcgcg gcagcgcaaa gagtagcagt tcaacacgca aaaccagcaa
    13621 taaaacagca acaaaaactg ctgcggtcag accgtcatct tcggtgccaa aatcctcctg
    13681 gccgccggtg gggcagcgtt gttgggtatg gcctgctaac ggtaaagtga ttttacctta
    13741 ttccaccgcg gagggcggaa ataaggggat cgatattgcg ggcgcgcgcg gaacgcctgt
    13801 ttatgcggcg ggagcgggta aagttgtcta tgtcgggaac cagctgcgcg gttacggcaa
    13861 tctcatcatg attaagcaca atgaagatta cattacggct tacgctcata atgacaccat
    13921 gctggttaat aatggacaaa gcgttaaagc ggggcaaaaa atcgctacga tgggcagcac
    13981 ggatgccgca tccgtaagac tacacttcca gattcgctac cgggcgacgg ccatcgatcc
    14041 gctgcgttat ctgccgccgc aggggagtaa accgaagtgc tgacggcgaa ttaatcgcca
    14101 gtcagccagt aagtctcttg ccaaccagag cgtaaggttt ataatgcctt acgcatctca
    14161 aagcgggcgt agttcaatgg tagaacgaga gcttcccaag ctctatacga gggttcgatt
    14221 cccttcgccc gctccatgac ctttcttaaa gtactccaac ctactgaatc ctaagggata
    14281 cggctttaag ccttccgcta gttttactca ctgtaaccaa cactgtaact aaatttgttg
    14341 aaatagtgag cagacttaag atctcagtac atgctcaact caaaaaccta tctttatcag
    14401 cgcaatggcg tcttttatat ccgcctcagg atgaagtcca cagatcgcct gaccgtttca
    14461 catccttccc atagccgtta taaaatagcg tcagtatcac tacggactaa ggatagacgt
    14521 acagctatgg cttactcacg gcatatcaag gcagcactta gggcaatcca tgcagacaga
    14581 cccaacgcct cctatgagga aatgagggaa cacctgaggg acatcgcaga gtgggagttg
    14641 tctacaggtc gttcagacct cttcgagcca gatatgagag atctataccg tgaccagtat
    14701 ggggaagtgg gagagaatct tgtccatagc gagccactga ctattgacca gcatcgctat
    14761 attaatgagg ctcttaatgt actcaaggcc tgcatgaagc gcattgaagc gggagatagc
    14821 cagccactta tagattatat agatggattt gatgctgctg ctggtgctaa tgaccaagcc
    14881 tctgcaactc tatctgttag tgctccccaa aaaacaagca ttactgaagg caaacactgc
    14941 gtaaccgttg cttctctctt tgagcagtac gagcaggaaa acgcccagaa ctggaagcca
    15001 gcaacattac gagaaaacaa agcttctcat gctgcgttaa tcgaggtttt tgattatctg
    15061 ggcctcaatg ctgacgccaa tgtgttagct cgtgcggata tgcttagggt tcgggatatc
    15121 ctccagcaat tgccgaagaa tcgtaagcag cgtttcaaag atgttccgtt ggttgacctg
    15181 ctaggtcgtg aggataaaac cgattgtctg gatattgtta ccatcaataa taaatatctc
    15241 attaagatgg cggctgtttt caagtgggcc gtgcgtaatg acctgattaa aaagaatatg
    15301 acagaagggc tagagcttaa ggttccccag cgtaaagcct ctgaggcgcg taatgctttc
    15361 tctacggagc aggtaggaca actactggct gccgcccaag tttactcaca gagaccttct
    15421 ggtaagccgt atcattatta tgttaccgcc ttggctgcta tcactggggc gagactcaat
    15481 gaaatagccc aactacaggt caaagacgtc aggaccactg aggcgggaac cgtttatatt
    15541 catatcaatg aagacgatag tagtctaccc ggtaagagca tcaagaacgc tcatagtgac
    15601 cgctgtgtgc ctctggtcga tggggcctat ggttttatat tggctgactt tatgaggttg
    15661 gttgagaccc gtagaggcgc tgatggtgat gacgctatgg tgttcgatgg tcttcgcctc
    15721 atgaagaacg gttacggtga gcaggtgagt aaatggttta atcggacgtt gttgcctaaa
    15781 gtcctcgcag atcgtagcgg cttagcgttt cactcgttta gacatacagt tgcgacccag
    15841 ttaaaacaac atggggtcga gttggcgtat gcacaggcga tcatggggca tagttcaggg
    15901 tctattactt acgaccgtta tgctaaagag gttgaggttg ataggctggt caatgtgatg
    15961 gctgatgttt ataaggagat tgtggggtaa ccaagctgtc cccccccggg gagatttgcc
    16021 ttgaggctga ccatagtcga tgaccatatt gctacaggcc tgtgtggtca tgtttttgac
    16081 tcacagtttt cactacttgt caaggatttc taatacgact cactataggg agaagggaca
    16141 caaaaagttt tctctctttc tctctcttct gggacacttg ctactactac tacaggtagc
    16201 tctaactcta actctaaccg taacttatcg catcctttca ggggcgggat gaccaattac
    16261 agacaccaag cgttctactt aaagtgaatg cttcctgtgt gctctgggtc agtcgataag
    16321 tgaatagcaa tagacatcat attaaatatg gtctctaccc tacaggggct taacttaaag
//
LOCUS       DAJVKX010000097        16237 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000097 DAJVKX010000000
VERSION     DAJVKX010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16237
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.097"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(51..842)
                     /gene="kdgR"
                     /locus_tag="OPY25_003181"
     CDS             complement(51..842)
                     /gene="kdgR"
                     /locus_tag="OPY25_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HCS0928731.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRELSR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     KQILDGVEYKQSTGRTITSTEALLPLLDEVRAQGYGEDNEEQEEGLRCIGVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHVAARKISEQMGYNDYPF"
     gene            1041..2390
                     /locus_tag="OPY25_003182"
                     /pseudo
     CDS             1041..2390
                     /locus_tag="OPY25_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(2438..3319)
                     /gene="htpX"
                     /locus_tag="OPY25_003183"
     CDS             complement(2438..3319)
                     /gene="htpX"
                     /locus_tag="OPY25_003183"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HCS0928732.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLLIMALLFGF
                     GGSFISLLMSKWMALKSVGGEVIEQPRNERERWLMNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRIIAQIAAGFLGGNRDEGEGSNGNPLIYFAVATVLELVFGILASIITMWFS
                     RYREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRSGEYLK"
     gene            complement(3512..5560)
                     /gene="prc"
                     /locus_tag="OPY25_003184"
     CDS             complement(3512..5560)
                     /gene="prc"
                     /locus_tag="OPY25_003184"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HCS0928733.1"
                     /translation="MNTFFRLTALAGLLALAGQSFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDEAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTVLGD
                     ELRTGKLDVFYDLYNLAQKRRFERYQYALKVLERPMDFTGNDTFNLDRSKAPWPKDEA
                     ELNALWDGKVKFDELSLKLTGKSDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKSI
                     SVGDRIVGVGQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRIITLT
                     RERIRLEDRAVKMSVKTIGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVNSIVINL
                     RSNGGGALTEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGVVYYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAAKYVKSDDLAP
                     FGPELLKEHNARIAKDPEFQYIMKDIARFNAMKDKRNIVSLNYAQREKENNEEDALRL
                     ARINDRFKREGKPLLKKLDDLPKDYQEPDPYLDETVKIALDLAHLEKEKPAEQAATDK
                     "
     gene            complement(5580..6266)
                     /gene="proQ"
                     /locus_tag="OPY25_003185"
     CDS             complement(5580..6266)
                     /gene="proQ"
                     /locus_tag="OPY25_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HCS0928734.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVE
                     RVGGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELEEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPVARRKEGAERKPRADKP
                     TTKAPRAPREEKHTPVSDISVLTVGQSLKVKAGNNAMDATVLEITKDGVRVQLNSGMS
                     LIVRAEHLVF"
     gene            complement(6364..6861)
                     /locus_tag="OPY25_003186"
     CDS             complement(6364..6861)
                     /locus_tag="OPY25_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCS0928735.1"
                     /translation="MSKTELYAALNRDFQSLMAGETSFLATLANTSALLFERLTEVNW
                     AGFYLLEGDTLVLGPFQGRIACVRIPVGRGVCGAAVAQNKVQRIDDVHAFDGHIACDA
                     ASNAEIVLPVTVGERIIGVLDIDSTAFGRFTEEDEHGLRTLVAQLETVLATTDYKKFF
                     ASVAG"
     gene            6990..8273
                     /gene="yebS"
                     /locus_tag="OPY25_003187"
     CDS             6990..8273
                     /gene="yebS"
                     /locus_tag="OPY25_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HCS0928736.1"
                     /translation="MALNTSHVTPTKKLTIRSVSEALPRSHYQRCPECDMLFSLPEMS
                     AHQSAYCPRCQAKIRDGRDWSLTRLTAMAVTMLLLMPFAWSEPLLHIYLLGVRIDANV
                     MHGIWQMTQQGDPLTAAMVLFCVVGAPLILVFSIAYLWFGSLLGMNLRPVLLMLEKLK
                     EWVMLDIYLVGIGVASIKVQDYAFLQPGIGLLAFVSLVVLSILTMIHLNVEQLWERFY
                     PQHPAQRADERLRVCLGCHFSGYPDAKGRCPRCHIPLRLRRKQSIQKCWAALLASIVF
                     LLPANLLPISVIYINGGRQEDTILSGIMSLASSNIAVAAVVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRLVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFED"
     gene            8242..10875
                     /locus_tag="OPY25_003188"
     CDS             8242..10875
                     /locus_tag="OPY25_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MCE family protein"
                     /protein_id="HCS0928737.1"
                     /translation="MSQETPASKTEAQIKTKRRISPFWLLPLIALMIAGWLVWDSYQD
                     RGNSVTIDFMSADGIVPGRTPVRYQGVEVGTVEDVSLSKDLRKIEVRVSIKSDMEDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKPRDHFVALDTQPKYRLSNGD
                     LMIHLNAPDLGSLNSGSLVYFRKIPVGRVYDYSINPNKQGVTIDVLIERRFTDLVKKG
                     SRFWNVSGIDADLSLSGAKVKLESLAALVNGAIAFDSPDNSKPAAQDDTFGLYKDLAH
                     SQRGVIVKLELPSGDGLKAESTPLMYQGLEVGELSKLTLNPGGKVTGEMTVDPSVVPL
                     MRENTRIELRNPKLSLSDANISSLLTGKTFELVPGDGEPRSEFVVVPGEKALLHEANA
                     LTLTLTAPESYGIEPGQPLILHGVKIGQVIERNLSSKGVSFIVAIEPQHRDLVQGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWIDGGIRILPGTSGKMKSTYPLYANLEKALENS
                     LSDLPTTTLTLTAETLPDVQAGSVVLYRKFEVGEVITVRPRANTFDIDLHIKPEYRHL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASRRKGDKRILY
                     ASETSARAVGGQITLHAFDAGKLAEGMPIRYLGIDIGQIQTLELITARNEVQAKAVLY
                     PEYVQTFARAGTRFSVITPQISAAGVEHLDTILQPYINVEPGRGAARRDFELQEATIT
                     DSRYLDGLSIVVEAPEAGSLNIGTPVLFRGIEVGTVTGMSLGSLSDRVMITLRISKRY
                     QYLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQAGK
                     HFLLQESEPKEWREWGTALPR"
     gene            10953..12392
                     /gene="rsmF"
                     /locus_tag="OPY25_003189"
     CDS             10953..12392
                     /gene="rsmF"
                     /locus_tag="OPY25_003189"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HCS0928738.1"
                     /translation="MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRIN
                     TLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHA
                     NISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     LDIAATQRELLDSAFHALRPGGTLVYSTCTLNRQENEAVCLWLKETYADAVEFLPLGD
                     LFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAPGYKVGAFPFTSLKG
                     REALNVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHN
                     KGYRWQHEATIALACPTHAHAFELSVQEAEEWYRGRDIYPQTPPAADDVLVTFQHQPL
                     GLAKRIGARIKNSYPRELVRDGKLFTGNS"
     gene            12510..12746
                     /locus_tag="OPY25_003190"
     CDS             12510..12746
                     /locus_tag="OPY25_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HCS0928739.1"
                     /translation="MKTSVRIGAFEIDDAELHGESPGERTLTIPCKSDPDLCMQLDAW
                     DAETSVPAILNGEHSVLFRNHYDPKSDAWVMRLA"
     gene            12857..13048
                     /locus_tag="OPY25_003191"
     CDS             12857..13048
                     /locus_tag="OPY25_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HCS0928740.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDIYDTEQQCLYSMDDQRIRHGGCF
                     PVEDFIDGFWRPAQQYSDF"
     gene            complement(13067..13717)
                     /gene="pphA"
                     /locus_tag="OPY25_003192"
     CDS             complement(13067..13717)
                     /gene="pphA"
                     /locus_tag="OPY25_003192"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HCS0928741.1"
                     /translation="MMRPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKRLRECQFDPQ
                     QDLLVSVGDLIDRGPDSLGCLALLRESWMTAVRGNHEQMALDARASSQSTLWLMNGGD
                     WFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQ
                     VLWSRERLINKRGGISGADHFWFGHTPLRRRMDFANIHYIDTGAVFGGQLTLARIQ"
     gene            complement(13941..14105)
                     /locus_tag="OPY25_003193"
     CDS             complement(13941..14105)
                     /locus_tag="OPY25_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928742.1"
                     /translation="MPPLKKIVLRLFVGAMVATVTTPALALVCLEDHSAKECAISCAE
                     VMWFMFPICF"
     gene            complement(14390..15111)
                     /gene="sopE2"
                     /locus_tag="OPY25_003194"
                     /pseudo
     CDS             complement(14390..15111)
                     /gene="sopE2"
                     /locus_tag="OPY25_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460811.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system guanine
                     nucleotide exchange factor SopE2"
     gene            15795..16190
                     /locus_tag="OPY25_003195"
     CDS             15795..16190
                     /locus_tag="OPY25_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HCS0928743.1"
                     /translation="MELQLMLNHFFERVRKDANFNAFLIDLEYNNIAYYIYFVATGNV
                     KIITHAGHFISIKSNRKLIKVNSTPNTQLIKLTSAKHFSGEHSYEKYCTDLATAGVFK
                     WIVELNKKTRQYWSKDNQLLYIENVVMPL"
BASE COUNT         3854 a         4280 c         3877 g         4226 t
ORIGIN      
        1 gctacgaaaa atgtagctgc ttttttttaa cgtcatgcta ataacgttgc ttagaaggga
       61 taatcgttgt aacccatttg ttcagaaatt ttacgcgcgg cgacgtgtaa catagccaca
      121 tattcctgta ggcgttcttc tgaaaaacgc agcgtcggga acgaaatgct taaccctgcg
      181 atgactacgc caaaacggtc aaataccggt acgccgatac aacgtaaccc ttcttcctgt
      241 tcttcgttat cttcaccgta gccttgcgca cgcacttcat ccaacagcgg cagcaacgct
      301 tcagtgctgg taatcgtgcg tcccgtgctt tgcttatact ctacgccgtc gagaatctgc
      361 ttaacctcat cacggtcgcg ccaggccaga agcactttac cgatggccgt actgtacagc
      421 ggattacgac gcccaatacg tgagtacatc cgcagattgt acatagagtc aattttatgg
      481 atatagacaa tgctgtcttc atccagcgcg ccaagatgga tagtttcttt tgtcagacga
      541 gacagttcgc gcatctgaat gtccgcactg cggatgagat caacattttg caaagctcgc
      601 gcgcccagct caaacagctt tagcgtcaga gagtattttt cagactcccc ctcctgagcc
      661 acgtagccca gcgttttcat ggtttgcaaa aagcgataaa cggtgctttt cgacatcatg
      721 acgcgctgcg atagctcggt aatccctatt tcacgctctt cacccagcgc ctgcagaatg
      781 ccgaaaactt tcagcacaga agatacagaa tcaggctgct tatccagatc tgcgtttgcc
      841 atttatcacc tcattacgag cgttttataa aattcagaac gagtttttat tataatttca
      901 cgccaggtcg cccgcaatcc atctttgctt acttcgttac aaatctacga cataacaact
      961 cagtattaat gctaacatta ttattcagct cataattccc cttattacaa aatacttatg
     1021 gaaaaaacac gggccgacgg ctgcccctcc cgcagagata cggcgctatc ctgacgatta
     1081 ttatcggtat ttcgatggcg gttctggatg gcgcaatcgc taatgtcgcg ctgccaacca
     1141 ttgcgactga tttacatgcc tcccctgcca gctctatctg gattgtcaat gcgtaccaaa
     1201 tcgccattgt cgtctcacta ctttccctgt cttttttagg cgacatgttt ggttatcacc
     1261 ggatctataa atgtggttta gtggtatttc tgctttcatc attgttttgc gcgctttcag
     1321 actcgctgca gatgctgacg ctggcgcgca tcgcgcagga atttggcggc gcggcgctaa
     1381 tgagcgtaaa cacggcgctg attcgtctta tctaccccca gcgtcatctg ggacgaggta
     1441 tgggaattaa ctcttttatc gtcgccgtct cttccgccgc gggtccgacg atcgccgcgg
     1501 cgattttgtc catctcatca tagaaatggc tgtttctgat taatgtcccg ttaggtatca
     1561 tcgcgttaat tctggccata cgctttttac cagcaaacat cgcccatgac actaagccgc
     1621 gctttgactt accgagcgcg gtaatgaatg cgctcacatt tggtctgctg attaccgcat
     1681 tgagcggctt tgcccaggga cagtcgctaa cgttgattgg cgcagagctg ctcgttctgg
     1741 tcgtggtcgg gtttttcttc gtgcgccgcc agctttcttt gcccgtccct ttgttaccca
     1801 tcgacttgtt acgcattccg cttttttcac tctcgatcgg cacgtcaatt tgctcgttct
     1861 gcgcgcaaat gttagccatg gtctcgctac ctttttatct gcaaaccgtg ctgggccgta
     1921 gcgaagtaga aaccggcctg ttattgacgc cctggccgct ggcaacgatg gtgatggcgc
     1981 cgctggcggg atacctgata gaacgtcttc atgccggttt gctgggggcg ctgggaatgg
     2041 tgataatggc agccgggttg tttgcgctgg tcatgttgcc aggcaccccc tccgatctga
     2101 atattatctg gccgatgatc ctttgcggcg cagggtttgg cctgttccag tcgccgaata
     2161 atcacaccat tatcacttcc gcgccgcgtg agcgcagcgg tggcgccagc gggatgctgg
     2221 gcacggcgcg actgttaggc caaagtactg gcgccgcgct ggtagcgctg atgttgaacc
     2281 agtttggcga tagcggtacg catctttcgc tgctcgcggc ggcgatcctg gcgactctcg
     2341 cggcggtggt gagcggttta cgtattacgc aaccacgcgt tcaggcgtaa aaaaagcgcg
     2401 tcattcgacg cgcttttcat acttgccagt gggcttatta tttcaggtac tcgccgctac
     2461 gcagcgcttc aatgcgttta tccagcggtg ggtgcgtcat aaacagctcg cttaacgatt
     2521 tcgatttacc gttaatacaa aacgccatca tgctggtcgc ttcttgcggc tcgtagctgg
     2581 ttttcaggcg ctgcaacgcg gcaatcattt tttcacggcc caccagcttc gccgatcccg
     2641 catcggcatg aaactcacgg taacgggaga accacatggt gataatgctt gccagaatac
     2701 cgaagaccag ttccagcacc gtcgcaacgg cgaaatagat tagcggatta ccgttacttc
     2761 cttcgccttc atcacggttg ccgcccagaa aaccagcagc aatttgcgcg ataatgcgcg
     2821 aaataaagat aacgaaggtg ttaaccaccc cctgaatcaa cgtcatcgtc accatatcgc
     2881 cattggcaat atggctgatt tcatgcgcaa tgacggcttc cgcctcgtca gggctcatat
     2941 tttgcaacag accggtgctc acagcgacca atgaggcgtc acggcgtgcg cccgtcgcaa
     3001 acgcgttaat gtccggcgca tggtagatag caacctgcgg catggcgata ccagcctggc
     3061 gcgcttgcgt tgctacggtg ttcatcaacc agcgttctct ttcattgcga ggctgttcaa
     3121 taacttcccc tcctacggat tttaacgcca tccatttgga catcagcaat gaaataaaag
     3181 aaccgccaaa accaaacagc agcgccatga tcagcaagcc ttgcacgctg ctcgactgta
     3241 tccctgtcag gctcagaacc agcccgaaaa cgaccatcac ggccaggttc gtcagcagga
     3301 agagcgcgat tcgcatcata attttctttt aacctcaatt taacaaagcg cactatgcga
     3361 ttacccacat cgtatgggtc ttatggctat tttcaagtat caccaggcgg taagtcacga
     3421 gaaaaacaca actttacatt ttgtagcatt atcctgacga cttctgcgct tgttaaaaaa
     3481 aacaggcaca attttttgtg cctgtttagc gttacttatc ggttgccgct tgctccgctg
     3541 gtttttcttt ttcaagatgc gccaggtcca gagcaatctt caccgtttca tcaaggtacg
     3601 ggtccggctc ctggtaatcc tttggcagat cgtccagttt cttcaacaac ggtttaccct
     3661 cacgtttaaa ccgatcgtta atacgcgcca gacgcagagc gtcttcttca ttgttctctt
     3721 tctcacgctg cgcataattc agagagacga tgttgcgctt atccttcatg gcattgaaac
     3781 gtgcgatatc cttcatgatg tactgaaact caggatcttt ggcgatacgc gcgttgtgct
     3841 ctttcaataa ttccgggcca aacggggcca aatcgtccga tttcacgtat ttcgccgcat
     3901 caatgctatc ccacggcaag gcgttatctt caaatttttc tccggtttcc gtctcttcat
     3961 tgccagtcgg catgatgata tccggcgtga cccctttacg ctgcgtacta ccgccgttga
     4021 cacggtaaaa cttctgaatg gtgtactgca ccgaacccag cgcaggccat tccgggcgga
     4081 gcatctgatc gtaaattcgg tttagcgaac gatattgctg taccgtccct ttaccgaagg
     4141 tcggctcacc gacaatcagc gcgcgaccat aatcctgcat cgcggcagcg aagatttccg
     4201 atgccgaagc actgaaacga tcgaccagca ccaccagcgg gcctttgtag tagaccacgc
     4261 cgtcggtgtc gctatcctca cgcactttac cgttattgtc gcgcacctga actatcggac
     4321 cagaagggat aaacaggccg gaaagcgaaa cggcttccgt cagcgcccca ccgccgtttg
     4381 aacgcagatt gataacgatg ctgttaacat tctgtttttc cagcttctga agctgaactt
     4441 tgacatcatc ggtcaagcca acatagaagc ctggaatatc cagtacgcca actttttcct
     4501 tgccgatggt tttcaccgac attttaaccg cgcgatcttc aagacgaatc cgttcacgcg
     4561 tcagcgtgat aatacgcgtt ttcgtccctt tgccagccgg cagtatttcc agtcggacct
     4621 tgctgccttt cggccctttg atcagcgcca ccacatcgtc aagacgccag ccaatgacgt
     4681 cgaccatcgg ttttccggcc tgccctacgc cgacgatacg atcgccgacg ctaatcgact
     4741 tgctcttcgc tgccgggcca ccggcgacca atgagttaat gacagtgtaa tcgtcatcca
     4801 tttgcagcac cgcgccgata ccttccagag acaggctcat ttcggtatta aactgctcgg
     4861 tattgcgggg agaaagataa ttcgtatgcg ggtcgatttc acgcgcaaaa gcggtcatcg
     4921 ccagcgagaa cacatcttca ctgttggtct gcgccaggcg gcgaatagcg aatttgtagc
     4981 gacgcgtcag cgtttcgcga atttctttgt cgctcttgcc ggtgagtttc agactgagct
     5041 catcgaattt cactttacca tcccacagcg catttagctc agcctcatct ttcggccagg
     5101 gcgctttact gcggtccagg ttaaacgtat cgtttccggt gaaatccatt ggccgttcca
     5161 gcacttttag cgcgtactgg taacgttcaa accggcgctt ttgcgccagg ttataaagat
     5221 cgtaaaaaac atccagctta cccgtgcgca gctcatcgcc caacacggtt ttctttttcg
     5281 caaactgctc gacatcgctc gccaacaaaa cgttgtggct atagtcgaga agattcagat
     5341 agcgatcaaa aatctttgcc gaaaatgcct catccagatc gaactggcga tagtgggagc
     5401 gggtaaaacg cgacgttacg cgctcgctca ccgtcgcatg ttgcgtctct tcctttagta
     5461 cgggaatttg atcggcacgc gtaatatctt ccacggcgaa ggactggcct gctaatgcaa
     5521 gcaggccagc taacgcggta agcctaaaaa aagtgttcat gccaggcctg gcctccgttt
     5581 cagaacacca ggtgttctgc gcgtacaatc aaagacatac ccgaattcag ctgtacacgg
     5641 acaccatctt tggtaatttc taatacggtg gcatccatcg cattattacc cgctttcacc
     5701 ttgagggact gccctacggt caatactgaa atatcagaaa ccggcgtgtg cttctcttcg
     5761 cgaggcgcac gcggcgcttt cgtcgtcggt ttatcagcgc gaggtttacg ttcagcgcct
     5821 tctttacgac gcgctaccgg gcgaggttta cgctcgcgtc gcggcgcgtc ttctttttcg
     5881 ccagccgccg cggcagcttc gcgttttttc gcttgctgct ctgcgcgctg cgcctgaaca
     5941 cgggctttgg cttcttcaag ctgcttacgc gcatgttcga catgctgttc ttccagctcg
     6001 ccgcacggat tgccatcaag gtcgacgcgc gttgcgcccg gcttaacgcc gtacaggtaa
     6061 cgccagcttg aagtataaag acgtaaagcg gaacgaagtt gcgttttgct gaggttcatt
     6121 tcgcccccaa ctcgctctac cagatcctga aaaataccaa ttttcagcgg gcgagcttcg
     6181 ccttccgcac taaaacagtg aggaaaacgc tcggccagaa acgcgataac ttctttactg
     6241 ctattcaact taggttgatt ttccatgaaa tttcctgatt acaacggacg tagccaacaa
     6301 gcagcaggca tgaacaggcg tcattataat gacgctatca gtaattgcta cgttatccgt
     6361 tgattatcct gcgacgctcg caaagaattt tttgtaatcc gtcgttgcaa gcacggtttc
     6421 aagctgtgcg accagcgtac gcaggccgtg ttcatcttct tcggtaaaac ggccaaacgc
     6481 cgtgctatct atatccagca cgccgataat ccgttcgcca accgtgacag gcagcacaat
     6541 ttcggcgttg ctggcggcat cacaggcaat atggccgtca aacgcatgaa catcatcaat
     6601 acgttgaacc ttattctgcg ctaccgctgc gccgcacacg ccgcgaccaa ccggaatccg
     6661 cacacaggcg attcgcccct gaaacggccc caacaccagc gtatcgcctt cgaggagata
     6721 aaatcccgcc cagttcacct cggtaagacg ttcgaacagt agcgcgctgg tattcgccag
     6781 cgtggccaga aagctggttt cacctgccat taacgactga aaatcgcggt ttaacgccgc
     6841 gtatagttct gttttgctca ttatataatc acttcgtggt cttactccta aacacaggct
     6901 attaaaataa gcattaaatg cgttcttgtt caagattatt cctgtcatga gttaagatta
     6961 cattattcta acactttgat tcacgataca tggctctgaa cacctcacac gtcacgccaa
     7021 caaaaaagct aacgatcagg tcagttagcg aagcgctgcc gcgcagccac taccagcgct
     7081 gccctgaatg cgacatgctg ttcagcttgc cggagatgag cgctcatcaa agcgcttatt
     7141 gtcctcgttg ccaggccaaa attcgcgatg ggcgcgactg gtcgctgacg cggctgaccg
     7201 cgatggcagt aaccatgctg ctattgatgc cgtttgcctg gagtgaaccg ctactccata
     7261 tctacctgtt gggcgtacgc attgatgcca atgtgatgca cggcatctgg caaatgacgc
     7321 agcagggcga tccgttaacc gccgcaatgg tgctcttttg cgtggtgggc gcgccgctta
     7381 ttctggtttt ttcaattgct tacctgtggt ttggcagcct tctcggcatg aatctgcgtc
     7441 cagtcctgct gatgctggaa aaactgaaag agtgggtgat gctggacatc tatctggtcg
     7501 gtattggcgt tgcctctatc aaagtgcagg actatgcctt tctgcagccg ggcattgggc
     7561 ttttagcgtt cgtctcgttg gtggttctta gcattctgac tatgattcat ctgaatgtgg
     7621 agcaactatg ggaacgattt tatccgcagc accctgctca acgtgcggac gaaagattgc
     7681 gcgtctgtct tggctgccac tttagcggct atccggatgc gaaaggacgc tgcccgcgtt
     7741 gtcatattcc gctacggtta cgcagaaaac agagcataca gaagtgttgg gcggccttgc
     7801 tggcgtctat tgtctttttg ctgccggcaa acctgctgcc tatctcggta atctacatta
     7861 atggcgggcg tcaggaagat actatcctgt cgggcattat gtcgcttgcc agcagcaata
     7921 tcgccgtcgc cgccgtcgtt tttatcgcca gtattttggt gccgtttacc aaagtcatcg
     7981 tgatgtttac gctactgttg agtatccatt ttaaatgcca acagggactg cggacgcgaa
     8041 ttctgttgct gcgtctggtg acatggatag gccgctggtc gatgctggat cttttcgtta
     8101 tctcgttaac catgtctctg attaatcgcg atcagattct ggcttttact atgggaccgg
     8161 ctgcgtttta tttcggcgca gcggtaattt tgactattct tgcagtggaa tggctggata
     8221 gccgcttact ttgggatgca catgagtcag gaaacgcccg cttcgaagac tgaagcgcaa
     8281 attaaaacca aacgccgtat ttcacctttc tggctgctac cgcttatcgc gctaatgatc
     8341 gcggggtggc tggtatggga tagctaccag gatcgcggca atagcgtgac tatcgatttt
     8401 atgtcggcgg acggtatcgt accgggccgt actcccgtgc gttatcaggg agtagaagtc
     8461 ggcaccgtgg aagatgtcag tctgagcaaa gatctgcgca aaattgaagt tcgcgtcagt
     8521 atcaaatcag atatggaaga tgcgttgcgc gaagagacgc aattctggct ggtgacgccc
     8581 aaagcctcgc tggcgggcgt ttccggcctg gatgcgttgg tcggcgggaa ttacatcggt
     8641 atgatgccag gtaaaggcaa gcccagagat catttcgtcg ccctagatac acagcctaaa
     8701 taccggctta gcaacggcga tctgatgatt catctcaatg cgccggatct cggttcgctt
     8761 aatagcggtt cactggtcta tttccgtaaa atccctgtcg gacgggtgta tgactattcg
     8821 attaacccta acaaacaggg cgtgacgatt gacgttctga ttgagcgacg gtttaccgat
     8881 ctggtgaaaa aaggcagccg tttttggaat gtctccggca ttgacgccga tctaagcctg
     8941 agcggcgcga aggtgaaact ggagagcctc gcggccctgg tcaatggcgc gattgcgttt
     9001 gactcaccgg acaattccaa acccgccgcc caggatgaca cgttcggctt atataaagat
     9061 ttagcccaca gccaacgagg ggtaatcgtt aaacttgagc tgcccagcgg agacggtctg
     9121 aaagcggaat ctacgccgct aatgtaccag ggactggagg tgggtgagct ttctaaactg
     9181 acgctcaacc ctggcggcaa agtcaccgga gagatgaccg tcgatcccag cgttgttccg
     9241 ctgatgcggg aaaatacgcg tattgagtta cgcaatccca aactgtcgct aagtgacgcg
     9301 aatatcagtt cgttgttaac cggaaaaacc ttcgagctgg tgccgggcga cggcgaacca
     9361 cgcagtgaat ttgtggtggt gccgggtgaa aaagccctgc tgcatgaggc gaatgcctta
     9421 accctgacgc tgacggcccc ggaaagttac ggcatcgaac cgggccagcc gttaatttta
     9481 catggcgtaa aaattggcca ggtcattgag cgcaacttat ccagtaaagg cgtgtcattc
     9541 atcgtcgcga ttgaaccgca gcaccgggat ttggtacagg gcgacagtaa attcgtggtc
     9601 aacagccggg tggatgtcaa agtcggcctt gacggcgtag agttcctcgg cgccagcgcc
     9661 agcgagtgga ttgacggcgg aattcgtatt ttacccggta cgagcgggaa gatgaaatcc
     9721 acctacccgc tctatgctaa cctggaaaaa gcgctggaaa atagcctcag tgacttaccg
     9781 actaccaccc tgacgctgac ggccgaaacg ttgccggatg tccaggcagg ttccgtcgtg
     9841 ctgtatcgaa aatttgaagt aggcgaagtc atcaccgttc gcccacgcgc caataccttt
     9901 gacatcgacc tgcatattaa gccggaatat cgccacctgt taaccagcaa tagcgtgttc
     9961 tgggcggaag gcggcgcgaa ggtgcaactt aacggcagcg gcctaacggt acaggcctcg
    10021 ccactctccc gtgcgctgaa aggggccatt agttttgata acctgagcgg cgccagcgcc
    10081 agtcggcgca aaggcgataa acgcattctt tatgcttcag aaacttccgc ccgcgcggta
    10141 ggcggacaaa ttacgctaca cgcgttcgac gccggaaaat tggcggaggg gatgcccatt
    10201 cgttacctcg gtattgatat cggccagatc cagacgctgg aattgatcac cgcacgtaat
    10261 gaagtgcagg caaaagccgt actttatccg gagtacgtgc aaacatttgc ccgcgccggg
    10321 acacgttttt ccgttattac gccacaaatc tccgcggcgg gcgtcgagca tctggatacg
    10381 attctccagc cctatattaa cgttgagcca ggacgcggcg cggcgcggcg cgactttgaa
    10441 ctgcaggaag ccacgattac cgactcacgc tatctggatg ggttaagcat cgtcgtggag
    10501 gcgccagaag caggctcgct taatattggc acacccgtcc tgtttcgcgg tatcgaagtg
    10561 ggaaccgtca ccggaatgtc cctggggtcg ctctccgatc gcgtgatgat caccttgcgc
    10621 atcagtaagc gttaccaata tctggtgcgt aataactccg tattctggct tgcctccggc
    10681 tatagtctcg actttggtct gacaggcggc gtggtgaaaa cggggacatt taatcaattc
    10741 atccgtggcg gtatcgcctt cgctactcca ccaggtacgc cgctggcgcc aaaagcgcaa
    10801 gccggtaagc atttcctgtt acaagagagc gaaccgaaag agtggcgtga atggggtacc
    10861 gctctgccac gttaaacacc aggctccggc gtactcgcgc cggagcgttt tatgctacac
    10921 tgcgcgcctg tttttttgcc ggcgatacac ctgtggctca acacgctgtc tattttcctg
    10981 acgcttttct gacgcaaatg cgtgaagcaa tgccttccac gctctctttt gatgaattta
    11041 tttcggcctg ccaacgcccg ttgcgccgca gtatacgcat caatacgctt aaaatatccg
    11101 tggctgattt ccttgcccta atcgcgccct acggctggtc gctcacgcca attccgtggt
    11161 gtcatgaagg attctggatc gagcgcgatg atgaagaggc attgccgctt ggcagtaccg
    11221 ctgagcattt aagcggcctg ttttacattc aggaggccag ttcgatgctg ccggtcgcgg
    11281 ccctgttcgc cgatgataat catccgcagc gggtcatgga tatggcagcg gcgcctggct
    11341 ccaaaaccac gcagatcgct gcccgcatgg ggaaccgcgg cgccattctg gccaacgaat
    11401 tttcggccag ccgcgtcaaa gttctgcacg ctaatatcag ccgatgtgga atcgccaata
    11461 ccgcactgac gcatttcgat ggccgcgtat ttggcgctgc gttaccggag atgtttgacg
    11521 ctatcctgct ggatgcgccc tgctctggcg aaggcgtagt acgtaaagat cctgatgcgc
    11581 taaaaaactg gtcgccagaa agtaatctgg atatcgcggc gacacagcgg gaactgctcg
    11641 acagcgcttt tcatgcttta cgacccggcg gcacgctggt ctactccacc tgcacgttaa
    11701 atcgccagga aaacgaagcg gtctgcctct ggctgaaaga gacctacgcc gacgccgttg
    11761 aatttttgcc gctgggtgat ctgtttcctg acgctgaccg cgccctcacc ccggaaggct
    11821 tcctgcacgt cttcccgcaa atttacgact gcgaaggatt cttcgtcgca cgtctgcgta
    11881 aaatgtcatc ccttccagcc atgcccgcgc cggggtataa agtgggggcg tttcctttta
    11941 cctccctcaa aggccgcgaa gcattaaacg ttacccaggc ggccaacgcc gtcggactgc
    12001 tatgggatga aaatctccat ctttggcagc gtgaaaaaga ggtctggctg ttcccggcag
    12061 agattgaatc actgatcgga aaagtccgtt tttcccggct cggcattaag ctggccgaaa
    12121 gtcataataa aggctatcgc tggcaacatg aggcgacgat agcccttgcc tgcccgactc
    12181 atgctcacgc gttcgaactt tctgtgcaag aggcggagga gtggtatcgc ggtcgggata
    12241 tttatccgca aacaccccct gccgctgatg atgtcctggt gacgttccag catcagccac
    12301 ttggtctggc aaaacgtatc ggcgccagaa taaagaacag ttacccgcgt gaactggtgc
    12361 gggatggaaa actctttact ggtaatagtt aaaaggcgca caaaaaaacc gcactttttg
    12421 actggcgctt ttgcgtacgt tgactacgct gaaaaatgga cggctaaact ggtcgtacca
    12481 caattagcgt attaacggag agcacgatga tgaaaaccag tgtgcgcatt ggcgcttttg
    12541 aaatcgacga tgccgaatta catggcgaat cgccggggga gcgaacgtta acaatcccct
    12601 gtaaatccga tccggattta tgtatgcaac tggacgcctg ggatgccgaa accagcgttc
    12661 ccgccattct caacggggaa cattccgttt tgttccgtaa tcattacgat cctaaatctg
    12721 atgcctgggt catgcgtctt gcctgactca aaaagaaccc gtcgccaggc gggttattta
    12781 ttcttccttt tctcatttcc cccctgcgct aacctctcct acactatcgt gtaaagtagt
    12841 taacattgag gatgtaatgt tcgcgctggt actttttgta tgttacctgg atggaggatg
    12901 cgaggatatt gtcgtggaca tctacgatac cgagcagcag tgtctttatt cgatggacga
    12961 tcaacggatt cgccatggcg gctgttttcc ggtagaggat tttatcgacg gcttctggcg
    13021 acctgcgcag caatatagcg atttttaacc ctagtcgctg atgccgctat tgtatccgcg
    13081 ctaacgtcaa ttgcccgcca aataccgcgc ccgtatcaat atagtgtatg ttggcgaaat
    13141 ccatgcgccg acgcaacggc gtatggccaa accaaaaatg atcggctccg ctaatcccgc
    13201 cgcgcttatt tatgagccgt tcgcggctcc agagaacctg atgtaagtcg accttttttt
    13261 gccattgata ggttgacgct ggataatctg catgagcgat cacatgcgtg ctatggcggc
    13321 agcgaacttc cagtatccag ggcagccgct gacaaagaat aaaaagcgct tcagcttgcg
    13381 cagcgtgttc agccgtcagg cgggtaaacc agtcgccacc attcatcaac cacagcgtcg
    13441 actgcgatga ggcccgcgca tccagcgcca tttgttcatg attgccgcga accgccgtca
    13501 tccaggactc acgcagtaaa gccaggcaac ccaggctgtc cgggcctcta tcaatgagat
    13561 cgcccacaga aactaacaag tcttgttgcg gatcaaattg acactcacgt aaccttttca
    13621 ttaacattga aaaacagccg tgaatatcgc cgaccaccca gacatgccgc caattctttg
    13681 cctctattcg ctgataaatc tcttcaggcc gcatcatgtt tttcctgtcg ttcattatcc
    13741 aagatagata taaaaagata gcgtgtgcag attttcttgc ttagtaaacg tgctctgttg
    13801 taaatagcga atttcatcag tagcgagtaa atgctttgtt atcatcgcaa taaaatataa
    13861 ctgactgcac caggggagtg ttatcccctg gcgcagcgag ctactcacta tcacctgttc
    13921 gcgttcaata ttctccctcc ttaaaaacat atcggaaaca taaaccacat cacctcagca
    13981 cacgatatag cacactcttt agcggagtga tcctcaaggc aaaccagcgc caatgcaggt
    14041 gtcgttaccg tggcgaccat cgcccccaca aacaggcgca gcacaatttt ttttaaaggt
    14101 ggcataacct ctcctgacag ttaacagacc attaatcctt atcgagacat catccgtgcg
    14161 cgggtatcat agacttaaca acacgcagcg tttcaaaaaa agctgtctgg ttataccggc
    14221 atttagagta ataacaatta ttttaagttt taagtgtatc catttgattt ttatattaaa
    14281 ataaatatga cgacgttttg ttaaaagcgt cgccataaaa atgaatatat agtttcagaa
    14341 aatctgctat taattcatac ggttaatagc ggtattgtgt ttgctatctt caggaggcat
    14401 tctgaagatg cttattcgca atattttcta tagttaactg aaattgttgt ggcgtcggca
    14461 tcgtcccctt attaaacagc ggcgtaacct ctttcataac gattttctca gcatacgctt
    14521 taaaagacac ctgctgatta tgatttataa acatatgcgg atatttaatg ctcgctgcag
    14581 caatgagggg gacgacaaaa ggattcgccc ctgccccacc tggagtaaat acaccatttt
    14641 ttatctcccc aggtagcccc gcattctgcg cagcctctcc tatctctttc agaaaggggg
    14701 taatactgac ccctttactg atgagtaatt tacaacagtg atctttatta ttactgtaca
    14761 cggctgataa tatggcttcg catgtctgac gagcataggc cggatcttta ctcgcattac
    14821 ctttgatatc caggctattg agcttttgca gcataaaatc tttaacagtt ttactggtta
    14881 atactgccct accctcagag gcgctcccac gatgaaaatg ggtagtcggt atgtctgttt
    14941 gttgatgcag gctaaaacga tctgacagac tcgtcgacag gctgataaag ctatttctaa
    15001 cggcagtaat actttttgca aaaatgtcct tctccgttgt ttttctttta ctggttcaac
    15061 gtcacttcta tggattctgt agtgctgggt ggatagtgtt atgttagtca cggtagttct
    15121 ccttttagat aactatgcat agctacactt tgtttatatt tcttgctttc aaaaaatagc
    15181 caccttctcc acaaccattt ttactcattg atatttataa attttatttt cctgatggat
    15241 tttgttcttc tgtcacttag cctgtttttt ttcggcgcaa ggtgatcgac ttttatcgag
    15301 gaacattttt atcgggacaa tcctgaacag gcaaaacatc acttcaattc aactgctgcg
    15361 tcacacaaaa cattcatgaa cattattatt tatgctgatg ttgttacgat tttgccccca
    15421 ttcgcaggct ggctaccaat tatcctgcca gcgagttagc cgctttttca aaacctataa
    15481 agtcgccacg ccaaacctct ccgccactgt aatccttatc taaaaatcaa ttaattaact
    15541 gatttttata tattatgact tttcatggcg ttcagaaaaa ctacaaatga aatggattga
    15601 ctcatctatt agtggtcaaa aaaacgcgct acgagaaata atcagtaaca attgcaacac
    15661 tattccaatc ataacgtaaa ctatatgata ccagacgatt attattgctt ttaggtagca
    15721 tatctgtata gctgctttta aacaacaata ctctaacaca acattcaaca ttataactta
    15781 caataggtta acaaatggaa ttacagctta tgcttaacca ctttttcgag cgtgtcagaa
    15841 aggatgcaaa tttcaacgca tttctaatcg atctggaata taataatatc gcttattaca
    15901 tctattttgt tgctaccggt aatgtgaaaa ttatcactca tgcaggccat ttcatttcta
    15961 ttaaaagcaa tagaaagctg attaaagtca attcaacacc aaatacgcaa ttaataaaat
    16021 tgacttcagc taaacacttt tcgggcgagc attcctatga aaaatactgt accgatctgg
    16081 caacggcagg cgtttttaaa tggattgtgg aattaaacaa aaaaactcga caatactggt
    16141 cgaaagacaa ccaattatta tatatagaaa atgtggtcat gccgctttaa caaacctggg
    16201 taataatagc gtcagtcgtg acatccggcg tgttgcg
//
LOCUS       DAJVKX010000098        16108 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000098 DAJVKX010000000
VERSION     DAJVKX010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16108
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.098"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            128..310
                     /locus_tag="OPY25_003196"
     CDS             128..310
                     /locus_tag="OPY25_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HCS0928744.1"
                     /translation="MAEHRGGSGNFAENREKASEAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQNSHGGRKSDNS"
     gene            400..903
                     /locus_tag="OPY25_003197"
     CDS             400..903
                     /locus_tag="OPY25_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HCS0928745.1"
                     /translation="MNIKTVEDLFIHLLSDTYSAEKQLTKALPKLARATSNEKLSQAF
                     QSHLEETQGQIERIDQIVESESGIKLKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYSKALKLLKETLDEEKQTDLKLTDLAVSNVNK
                     SAERKSK"
     gene            977..1483
                     /locus_tag="OPY25_003198"
     CDS             977..1483
                     /locus_tag="OPY25_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HCS0928746.1"
                     /translation="MNYTEHYHDWLRDAHAMEKQAESMLESMASRIENYPDIKARIEQ
                     HISETKHQITMLEEVLDRNGISRSVLKDSMSKMAAMGQSIGGMFPSDEIVKGSISGYV
                     FEQFEIACYTSLLAAAKKAGDTASIPTIEAILKEEMQMADWLIKHIPQTTEQFLLRSE
                     ADGVEAKK"
     gene            1503..2381
                     /locus_tag="OPY25_003199"
     CDS             1503..2381
                     /locus_tag="OPY25_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCS0928747.1"
                     /translation="MFRHVKQLQYTVRVSEPNPGLANLLLEQFGGPQGELAAACRYFT
                     QGLSDDDAGRREMLMDIATEELSHLEIIGSLVGMLNKGAKGELAEGTESEAELYRSLT
                     QNGNDSHITSLLYGGGPALTNSGGVPWTAAYIDTIGEVTADLRSNIAAEARAKIIYER
                     LINLTDDPGVKDTLSFLMTREVAHQLSFEKALYSIRNNFPPGKLPPVEQYTDVYYNIS
                     QGDDPRGSWNSDENFNYVAEPMPAVDGGDGLATVKLPREQMALLKAMAERTKSDPTVD
                     PLTGAELGCGEPKEDK"
     gene            complement(2463..3101)
                     /gene="ompW"
                     /locus_tag="OPY25_003200"
     CDS             complement(2463..3101)
                     /gene="ompW"
                     /locus_tag="OPY25_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HCS0928748.1"
                     /translation="MKKFTVAALALTTLLSGSAFAHEAGEFFMRAGPATVRPTEGAGG
                     TLGHLNGFDVSNNTQLGLTFTYMATDNIGVELLAATPFRHKVGTGATGDIATVHLLPP
                     TLMAQWYFGDSSSKVRPYVGVGVNYTTFFDNDFNDNGKKTGLSDLSFKDSWGAAGQVG
                     VDYLINRDWLIGASVWYMDIDTTANYKMGGVQQHDSVRLDPWVFMFSAGYRF"
     gene            3439..3843
                     /locus_tag="OPY25_003201"
     CDS             3439..3843
                     /locus_tag="OPY25_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HCS0928749.1"
                     /translation="MSVLNPCMTCGACCAYFRVSFYWAEGDDASGRVPASLTEPVTPF
                     LRCMAGTNQKQPHCKALIGTPGENVSCAIYENRPSTCREFSISGEGGEVNEACNRARA
                     RYGLPPLYKDMLFHTTADAATVELSRVQLPAN"
     gene            3869..4612
                     /locus_tag="OPY25_003202"
     CDS             3869..4612
                     /locus_tag="OPY25_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HCS0928750.1"
                     /translation="MSITAKSVYRDAGNFFRNQFITILLVSLLCAFITVVLGHAFSPS
                     DAQIAQLSEGEHLAGSAGLFELVQNMTPEQQQILLRASAASTFSGLIGNAILAGGIIL
                     MIQLVSAGHRVSALRAIGASAPALPKLFILIFLTTLLVQIGIMLIVVPGIIMAIVLAL
                     APVMLVEEKMGVFAAMRSSMRLAWANMKLVAPAVIGWLLAKTLLLLFAPSFAVLTPNV
                     GAVLANTLSNLISAVLLIYLFRLYMLIRQ"
     gene            4669..5208
                     /locus_tag="OPY25_003203"
     CDS             4669..5208
                     /locus_tag="OPY25_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HCS0928751.1"
                     /translation="MKQFLDFLPLVVFFAFYKLYDIYAATSALIVATAIVLIYSWVRY
                     RKIEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLISQWVMKKPLIQ
                     RMLGKELALPQQVWSKLNLAWALFFIACGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGVYIYRHLPQEDKS"
     gene            5369..5770
                     /gene="yciA"
                     /locus_tag="OPY25_003204"
     CDS             5369..5770
                     /gene="yciA"
                     /locus_tag="OPY25_003204"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HCS0928752.1"
                     /translation="MTTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVKRGTTSISINIEVWVKKVASE
                     PIGQRYKATEALFIYVAVDPDGKPRPLPVQG"
     gene            complement(5829..6557)
                     /gene="tonB"
                     /locus_tag="OPY25_003205"
     CDS             complement(5829..6557)
                     /gene="tonB"
                     /locus_tag="OPY25_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HCS0928753.1"
                     /translation="MTLDLPRRFPWSTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQP
                     ITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     KPEPVKKVEEQPKREVKPAAPRPASPFENSAPMRPTSGTASATSKPAVSVPTGPRALS
                     RNQPQYPARAQALRIEGRVKVKFDVTAAGRVENVQILSAQPANMFEREVKNAMRKWRY
                     EAGKPGSGLVVNIIFRLNGAAQIE"
     gene            6781..7077
                     /locus_tag="OPY25_003206"
     CDS             6781..7077
                     /locus_tag="OPY25_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HCS0928754.1"
                     /translation="MLYVIYAQDNANSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGVAGFTGSTVIAEFESLEAAQSWADADPYVAAGVYAQVSVKPYKKIF"
     gene            complement(7121..7294)
                     /locus_tag="OPY25_003207"
     CDS             complement(7121..7294)
                     /locus_tag="OPY25_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HCS0928755.1"
                     /translation="MKRSRTEVGRWRMLRQASRRKARWLEGQSRRNMRIHTIRKCIFN
                     RQRNSLLFAIHGV"
     gene            7437..8897
                     /gene="cls"
                     /locus_tag="OPY25_003208"
     CDS             7437..8897
                     /gene="cls"
                     /locus_tag="OPY25_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCS0928756.1"
                     /translation="MTTFYTVVSWLVILGYWVLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLSVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAQENSSVASS
                     LFKLCERRQGIAGVKGNQLQLLTDSDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWAAMMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMVMIDNYIAYTGSMNMVDPRFFKQDAGVGQWVDLMARMEGPVATAMGIVY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTATYAAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSLLVGWASRAFFSELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDTGFGADLAAVQ
                     DDYISRSRLLDARLWVKRPLWQRITERLFYFFSPLL"
     gene            8931..9260
                     /locus_tag="OPY25_003209"
     CDS             8931..9260
                     /locus_tag="OPY25_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HCS0928757.1"
                     /translation="MEMDLNNRLTEDETLEQAYDIFLELAADNLDPADIILFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADTEDGEINDIFARVLLCREKDHKL
                     CHILWRE"
     gene            complement(9308..10144)
                     /locus_tag="OPY25_003210"
     CDS             complement(9308..10144)
                     /locus_tag="OPY25_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HCS0928758.1"
                     /translation="MSLSLSSVRRRLYHNLFDLTTRSSRRFEGLCALFALLSVLVIFV
                     ESGVGTEYHLTFDEWHIFVWLELCVTLIFTGEYLLRLFSWPEPAKYVFSFWGFIDLVT
                     ILPLYVMWLWPEISLNYMFAWRAMRAIRVLRILKLLRFMPSLRVFWSAIISARHQLIL
                     FYSFIAIVMIIFGALMYLIEGPKYGFTTLNASVYWAIVTVTTVGYGDITPHTPLGRIV
                     ASVLILIGYSVIAIPTGLITTHMSSAFQKRHWQRKCPQCQQSQHEHSAQYCNRCGSKL
                     PD"
     gene            complement(10192..11196)
                     /gene="oppF"
                     /locus_tag="OPY25_003211"
     CDS             complement(10192..11196)
                     /gene="oppF"
                     /locus_tag="OPY25_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HCS0928759.1"
                     /translation="MNAVIEQRKVLLEIADLKVHFDIKEGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGKVAWLGKDLLGMKADEWREVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKLSRQDVRDRVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTKALMSAVPIPDPDLE
                     RNKKIQLLEGELPSPINPPSGCVFRTRCPLAGPECAQTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(11193..12200)
                     /locus_tag="OPY25_003212"
     CDS             complement(11193..12200)
                     /locus_tag="OPY25_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0928760.1"
                     /translation="MSLSETATQAPQPANVLLEVNDLRVTFATPDGDVTAVNDLNFTL
                     RAGETLGIVGESGSGKSQTAFALMGLLATNGRIGGSATFNGREILNLPERELNTLRAE
                     QISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKIPEARKRM
                     KMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNT
                     AIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPVHPYSIGLLNAVPRLDSE
                     GAEMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNNAPPLEAFSPGRLRACFKPVEEL
                     L"
     gene            complement(12212..13119)
                     /gene="oppC"
                     /locus_tag="OPY25_003213"
                     /pseudo
     CDS             complement(12212..13119)
                     /gene="oppC"
                     /locus_tag="OPY25_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
     gene            complement(13134..14054)
                     /gene="oppB"
                     /locus_tag="OPY25_003214"
     CDS             complement(13134..14054)
                     /gene="oppB"
                     /locus_tag="OPY25_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HCS0928761.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERALPPE
                     VLANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYTVNDLVAASFPVSAKLGA
                     AAFLLAVIIGVSAGVIAALKQNTRWDYTVMGFAMTGVVIPSFVVAPLLVMVFAITLQW
                     LLGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IIFRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            complement(14176..15807)
                     /gene="oppA"
                     /locus_tag="OPY25_003215"
     CDS             complement(14176..15807)
                     /gene="oppA"
                     /locus_tag="OPY25_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HCS0928762.1"
                     /translation="MSNITKKSLIAVGILTAFIAASAATAADVPAGVQLADKQTLVRN
                     NGSEVQSLDPHKIEGVPESNVSRDLFEGLLISDVEGHPSPGVAEKWENKDFKVWTFHL
                     RENAKWSDGTPVTAHDFVYSWQRLADPNTASPYASYLQYGHIVNIDDIIAGKKPATDL
                     GVKALDDHTFKVTLSEPVPYFYKLLVHPSVSPVPKSAVEKFGDKWTQPANIVTNGAYK
                     LKNWVVNERIVLERNPQYWDNDKTVINQVTYLPISSEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPNEVRVDPYLCTYYYEINNQKAPFNDVRVRTALKLALDRDIIVNKVKN
                     QGDLPAYSYTPPYTDGAKLVEPEWFKWSQQKRNEEAKKLLAEAGFTADKPLTFDLLYN
                     TSDLHKKLAIAVASIWKKNLGVNVNLENQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSDSSNNTAHYKSPAFDKLIADTLKVADDTQRSELYAKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNIYVKNLYIIKH"
BASE COUNT         4061 a         4140 c         3948 g         3959 t
ORIGIN      
        1 ttatttacgc ggtaaatcac aactatttcc gtcaatttga ctaatcggtt taaccaacta
       61 attttaatag ggtgtcgaca cggttaaaac cgattttttc agcaagcaac gagacaggag
      121 aaataatatg gccgaacatc gtggtggttc aggaaatttc gccgagaatc gtgaaaaagc
      181 atctgaagcg ggccgcaaag gcggtcagca tagcggcggg aatttcaaaa acgatccgca
      241 acgagcttct gaagccggta aaaaaggtgg tcagaatagt cacggcggac gtaaatccga
      301 taattcctga tttactgtaa tgtaaatata acacatgctt ttatcaagca atctgcgagt
      361 cttctggctc gcagtatttt gcccaggaga attagattta tgaatatcaa aaccgttgaa
      421 gaccttttta tccatctact ttcagatacc tatagtgcag aaaaacaatt aaccaaggct
      481 cttcctaaac ttgccagagc cacgtccaat gaaaaattaa gccaggcctt tcaatctcat
      541 cttgaagaaa cccagggtca gattgaacgt attgatcaga tcgtcgaatc tgaatctggc
      601 attaaactga aaagaatgaa atgcgtcgct atggaagggc tgattgaaga agccaatgaa
      661 gtcatcgaaa gtacggagaa aaacgaagta cgcgatgcag cgcttatcgc cgcggcgcaa
      721 aaagtcgagc attacgaaat cgccagctac ggcacgctag ccaccctggc cgagcagctc
      781 ggctatagca aagcattaaa actgctcaaa gaaaccctcg acgaggaaaa acaaactgat
      841 ttaaaactta ccgatttagc agtcagcaat gttaataaaa gtgctgaacg caaatcgaaa
      901 taatattttt aattatcagc ttgcatgatt ccgattttat tatcggagca gattatcacg
      961 cattgaggaa tgtaaaatga attatactga acattatcat gactggcttc gtgacgccca
     1021 tgccatggaa aaacaggcag aatcgatgct tgaatctatg gccagccgta ttgaaaatta
     1081 tcctgatata aaagccagaa ttgaacaaca tattagtgaa accaaacatc aaattaccat
     1141 gctcgaggaa gtgttggacc gtaatggcat ttcccgttcg gtgttgaaag actccatgag
     1201 taaaatggca gcaatggggc aatctatcgg tggcatgttc ccttccgatg aaattgtcaa
     1261 aggctcaatt agcggttatg ttttcgagca gttcgaaatt gcttgttata cctccctgct
     1321 ggcggcggca aaaaaagctg gcgacactgc ctcaattcca acgattgaag ccattctgaa
     1381 agaagaaatg caaatggctg actggcttat caaacatatt ccgcagacaa cggaacaatt
     1441 tttactgcga tctgaagcag atggcgttga agccaaaaaa taaataataa gcaggaggca
     1501 atatgtttcg acacgtaaaa caacttcaat atactgtgcg agtgagcgaa cctaatcctg
     1561 gattagcgaa cctgctgctg gaacagtttg gcggcccgca gggcgaactg gcggccgcct
     1621 gccgctactt cacgcaaggt ttaagcgatg atgatgccgg tcgtagagag atgttaatgg
     1681 acatcgccac cgaggagctg agtcatctgg aaattatcgg ctcactggta ggaatgctta
     1741 ataaaggcgc taaaggcgag ctggcggaag gcaccgaaag cgaagcggaa ctttatcgct
     1801 cgctgacgca gaatggtaat gacagccata tcacctctct gctgtatggc ggcggccctg
     1861 cgttgacaaa ctccggcggc gtaccgtgga ccgcggctta tattgatact atcggcgaag
     1921 tcacagccga tctacgctca aacatcgcgg cagaggcgcg agcgaagatt atttatgaac
     1981 gcctgattaa cctgaccgac gatcctggcg taaaagacac gctcagtttc ttaatgaccc
     2041 gtgaagtcgc gcaccagctc tcttttgaaa aggcgctgta ttcgattcgt aacaacttcc
     2101 cgccgggtaa attaccgccg gtagaacagt ataccgacgt gtactacaac atatcgcaag
     2161 gcgacgatcc gcgaggtagc tggaatagcg atgagaactt caactatgtc gcagaaccga
     2221 tgcctgctgt tgatggcggc gatggcctgg cgacagtgaa attgccgcgc gagcagatgg
     2281 cgctgctcaa agcgatggca gaaagaacga aatcggaccc caccgttgat cctctcactg
     2341 gcgcagaact aggctgcggc gaaccgaaag aagacaagtg agttccgaca agtaaaatcc
     2401 gtgtgtcatg tccttttttg accccgcctg gcggggtctt ttttcgtcac aacatcacgc
     2461 gattagaaac gatagcctgc cgagaacata aatacccatg ggtccagacg cacgctgtca
     2521 tgctgctgca cgccgcccat tttataattg gctgtagtat caatatccat gtaccagaca
     2581 gaggcgccaa ttaaccagtc gcggttaatc aggtaatcta ccccaacttg ccctgccgcg
     2641 ccccaggaat ccttaaagct cagatcggac agcccggtct ttttaccatt atcgttaaag
     2701 tcgttatcga agaaggtggt gtagttcacc cccacgccga cataaggacg cactttgctg
     2761 ctggaatcgc cgaagtacca ctgcgccatt aacgttggcg gtaacaggtg gaccgtggcg
     2821 atatcacccg tcgcgcccgt acccacctta tggcggaacg gcgtggccgc cagcaattca
     2881 accccgatat tgtccgtcgc catgtaagtg aatgtcaggc cgagttgcgt gttattactc
     2941 acatcaaacc cgtttaaatg ccccagcgta ccacccgccc cttctgtagg tctgacggtt
     3001 gccggacctg cacgcataaa gaattctccg gcttcgtgcg cgaacgcgct gcctgagaga
     3061 agagttgtta acgccagtgc cgccactgta aattttttca tacccgctcc atcgttatgg
     3121 ttataaaagc gtgatgaata tacccacaat gaagtaataa gtgatctaac acagatcaca
     3181 tttgttctta taatttaaca tttattgatc cagattaatt tagaacttgt attgaaaatc
     3241 ctggttatag gaattcagat caattttgac atattcacgc tatgcaaata tttgtctgct
     3301 cctgttgccc tggcgataaa ggctggctaa ggtaatcaat gtcccgcaat ggcgcgtggc
     3361 ggtaagattc gcgaacactg cgggacagat taatttccgt tgtaatctat tgatacgtga
     3421 gttttttgca ggtgaatcat gagcgttctt aacccatgca tgacatgcgg tgcctgttgt
     3481 gcctattttc gtgtctcctt ttattgggct gaaggcgacg atgccagcgg acgcgttccg
     3541 gcgtcattaa ccgagcctgt tacccctttt ttacgttgta tggccggtac caaccaaaaa
     3601 cagccgcact gtaaagcgct aattggcacg ccgggtgaaa acgtcagttg cgctatttat
     3661 gaaaaccgcc cttcaacctg tcgcgaattt tcgatatcgg gcgaaggagg cgaagtgaat
     3721 gaggcgtgta atcgcgcccg cgcgcgatac ggattaccgc cgctttacaa agatatgctt
     3781 ttccatacaa ctgctgatgc tgccactgta gagttatcca gggtacaatt gcccgcaaat
     3841 taacacctgc aaaactcaag gagagtgcat gtctatcacg gcgaagtccg tttaccgtga
     3901 cgccggaaat tttttccgaa atcaatttat tactatcttg ctggtttcgt tgctgtgcgc
     3961 atttatcacg gtggtcttag gtcatgcctt ttcacccagc gatgcgcaaa tcgcgcaact
     4021 cagtgaagga gaacatctgg caggcagcgc tggcctgttt gagctggtac aaaatatgac
     4081 gccggagcag caacagatcc tgttgcgcgc ctctgccgcc tcgacgtttt ccgggcttat
     4141 cggcaacgct attctggccg gcggtatcat cctgatgatt cagttagttt cagcgggaca
     4201 tcgggttagc gcgctgcgcg ctatcggcgc cagcgcccct gcattgccta aactgtttat
     4261 tcttattttt ctgactaccc tgttagtgca aatcggtata atgctgattg tcgttccggg
     4321 gattattatg gccattgtgc tggcgcttgc gccagtgatg ttggttgaag agaaaatggg
     4381 cgtgtttgcc gcaatgcgca gcagtatgcg tttagcctgg gctaacatga aactggtcgc
     4441 gcctgcggtg ataggctggt tactggctaa aacattgcta ttgctgttcg cgcccagctt
     4501 cgctgtactg accccaaatg taggcgctgt actggcgaat acgttgagca atctgatttc
     4561 cgcagtattg cttatctact tattccgcct gtatatgttg attcgccaat aatccgcaat
     4621 gcgccgttac gcggcgcatt cgacgctcgt tgatgatgga atcgaagaat gaagcagttt
     4681 ctggattttt taccgctggt tgtctttttt gcgttttata aactttatga catctatgcg
     4741 gcgacctccg cactgattgt cgcaacggca atcgtgctga tttatagctg ggtgcgctat
     4801 cggaaaatag agaagatggc gctgattacc tttgttctgg ttgccgtctt cggcggtctg
     4861 acgctcttct tccataacga tgaatttatt aaatggaagg tgacggttat ttatgcgctg
     4921 ttcgccggcg cgctgttaat aagccagtgg gtgatgaaaa aaccgttaat ccaacgtatg
     4981 ttaggtaaag aactggcgtt gccgcagcag gtctggtcaa agctgaacct ggcgtgggcg
     5041 ctgtttttta ttgcgtgcgg tctggctaac atttatatcg ccttctggtt gccgcaaaat
     5101 atctgggtta actttaaggt cttcggactc acggcgctga cgctcatttt taccctgctg
     5161 agcggcgtct atatctaccg gcatctgcca caggaagata aatcataacc ctcccgtgac
     5221 ttatcatcgc cagactgcga acgcctggcg atattttctc cgcctttacg ccctgcgctt
     5281 tcccgtcagt acctttattc ccactattct ccacacaata ttcatagtag catcgcggct
     5341 gtaatttttt ctgatagtcg gttttacaat gacaacaatg gataatactc ctcagggcga
     5401 gctggtttta cgtacattgg ccatgcctgc cgataccaat gcgaacggcg atatttttgg
     5461 cggctggctg atgtcgcaaa tggatattgg cggcgcgata ctggccaaag agatcgcgca
     5521 cggtcgggtt gtaaccgtac gcgtggaagg aatgacattt ctgcgccccg tcgcggttgg
     5581 cgatgtcgta tgctgctacg cgcgctgcgt taaacgcggt acgacgtcta ttagcatcaa
     5641 tattgaagtc tgggtgaaaa aagtcgcgtc agaaccgatt ggacagcgct acaaggccac
     5701 cgaggcgctg tttatttatg ttgccgtcga tccggacggt aaacctcgcc cgctcccggt
     5761 tcagggttaa gtatacccgc ttacgccgcc agcaggtgat ggtatattcc tactggcggc
     5821 gccagagatt actcaatctg cgccgcaccg ttcagacgga agataatatt gaccaccagc
     5881 ccggaacccg gcttgcctgc ttcatagcgc cattttcgca tcgcattctt aacttcacgc
     5941 tcaaacatat tggctggctg cgcggataga atctgtacat tttccactcg cccagcagcg
     6001 gtcacgtcaa acttcacctt tacgcggcct tcaatacgta acgcctgtgc tcgcgccgga
     6061 tactgcggct ggttacggct cagagctcga ggtccagtgg gcacgctcac cgccggcttg
     6121 ctggtcgccg atgcggtgcc gcttgttggc cgcatcgggg cgctattttc aaacggtgag
     6181 gcaggacgcg gtgcggctgg tttgacttcg cgcttcggct gctcttcaac ctttttcacc
     6241 ggttccggtt tcggttttgg cttgggtttt ggcttaggtt tgggtttctc aatcaccacg
     6301 ggcgcttctt taggcggttc agggatcggc tctggctccg gttcgggttc aaccaccggc
     6361 tccggcggcg gctgaaccgc ctggggcggc tccaggtcag cgggtgaaac cattgtcacc
     6421 gtgataggct gcgctggcgc aggcaattca ataacctgat gtaccgaggt atagagcaaa
     6481 cctgccacta cagcaccatg aatgcctacg gaaaggagtg tcgaccaggg aaagcgacga
     6541 ggtaaatcaa gggtcattga agtcataatc gtttcagttg aaaaaccaga gctgaatttt
     6601 aaatgcaaat agcaatcata ttcaataagg cattgccgat agcggcattt aaaagatgat
     6661 attgcacaaa aacaccacac aaaatgtgca tgtttaacaa agtcggtatc tttacattgc
     6721 agttaaatgc cctttccaat aacgtaatca gcaactttta ccgattaagg agctctaccc
     6781 gtgctgtatg ttatttacgc tcaggataat gccaactcgc ttgaaaaacg cctctcggta
     6841 cggcccgcgc atctggcgcg cctgcaactt ctgcatgatg aagggcgatt attaactgcc
     6901 gggccgatgc ccgcagtgga cagtaacgat cctggggtag ccggatttac cgggtcaacg
     6961 gtgattgctg aatttgaatc tttagaagca gcgcaatcct gggctgatgc ggatccctac
     7021 gtcgcagcgg gcgtctatgc gcaggtttcg gtcaaaccgt ataagaagat cttttgaaaa
     7081 ggatggcctg ttgggcaccg catacggtgc cctttctggc tcacacaccg tgaatcgcaa
     7141 agagtaatga attacgctga cgattaaaga tgcatttcct gatagtatgg atacgcatat
     7201 tacggcgtga ttgcccttca agccaacgcg ctttacggcg gctcgcctga cgtagcattc
     7261 gccagcgccc cacttccgtt ctactacgct tcatgtttac gactctcact gtaacagaag
     7321 cgccattata ccccctcgcc ggatgcagac cagcgctttt cccgtgtttt tatttgccat
     7381 gtgaatcctg acgcgtaaac tcttaacaac acgctttcta aaggattttt aaagttatga
     7441 caaccttcta caccgtggtg agttggctgg tcattttggg atactgggtt ctcattgccg
     7501 gcgtcacatt acgtattcta atgaaacggc gcgcagttcc ctccgcaatg gcctggttgt
     7561 taatcatcta tatccttccg ctggtcggga tcatcgccta tttgtccgtg ggcgaattgc
     7621 atttaggcaa acgtcgcgcc gagcgtgccc gcgccatgtg gccgtctacc gccaaatggt
     7681 tgaatgacct caaagcctgc aaacacattt tcgcgcaaga aaacagtagc gtcgcatcgt
     7741 ccttgtttaa gctgtgcgaa cgacgtcagg ggattgcggg cgtcaaaggc aaccagttgc
     7801 aattacttac cgactccgat gatgtcatgc aggcgcttat tcgcgatatc caactggcgc
     7861 ggcataatat cgaaatggtg ttttacatct ggcagccagg cggcatggcg gatcaggtcg
     7921 ctgaatcgct aatggccgcc gcccgccgcg gcatccattg ccggcttatg ctggattccg
     7981 cgggtagcgt cgctttcttc cgcagcccct gggcggccat gatgcgtaac gctggcattg
     8041 aagtcgtaga ggcgctgaag gtgaatctga tgcgcgtctt tttacgccgt atggatcttc
     8101 gccagcaccg taaaatggtg atgattgaca attacatcgc ctataccggc agtatgaata
     8161 tggtggaccc gcgttttttc aaacaggatg ccggcgttgg acaatgggtc gatttgatgg
     8221 cgcggatgga gggtcccgtg gcgacagcaa tggggattgt ttactcctgc gattgggaaa
     8281 tcgagacggg taaacgcatt ctgcctcccc cgccggacgt gaatattatg ccgtttgagc
     8341 aggccagcgg gcataccatt cataccattg cttccggtcc tggttttccg gaagatctca
     8401 ttcaccaggc actattaacc gccacctatg ctgcgcgcga atatttaatt atgaccacgc
     8461 catatttcgt ccccagcgac gatctgctgc acgccatttg taccgctgcg cagcgcggcg
     8521 tggatgtcag tattatcctg ccccgtaaaa atgattcact gctcgtcggc tgggccagtc
     8581 gcgccttttt cagcgagtta ctggcggcgg gcgtgaaaat ctatcagttc gaaggcgggc
     8641 tgttgcatac caaaagcgtg ctggtcgatg gcgaactgag cctggtcggt accgtgaatc
     8701 tcgacatgcg tagcctgtgg cttaatttcg agattacgct ggtcattgat gatacgggtt
     8761 tcggcgccga tctggctgcg gtacaggacg attatatttc gcgctcccgc ctgttagatg
     8821 cgcgtttgtg ggtaaaacgt ccgttatggc agcgtattac cgagcgattg ttttacttct
     8881 ttagtccatt gctgtaaaac gtgaccaaca tgagtaaaca ggtagtcact atggaaatgg
     8941 atctgaacaa tcgcctgact gaagacgaaa cgcttgagca ggcttacgat atttttcttg
     9001 agctggcggc ggataatctt gatccggctg atatcattct gttcaatttg caattcgagg
     9061 agcgcggcgg cgcggagttg tttgatcccg ctgaagactg gcaagagcac gtcgattttg
     9121 acctgaatcc agactttttt gccgaggtgg tgattggcct ggcggatacc gaagacggcg
     9181 aaattaacga catttttgcc cgcgttctgc tgtgccggga aaaggaccac aagctgtgcc
     9241 atattctctg gcgcgaataa gcggttcagg ccggatggcg tctgatagcg ccctccggca
     9301 agcctgttta atccggtagc ttactgccgc atcggttaca atattgcgcg ctatgttcat
     9361 gctggctttg ctggcactgc ggacattttc gctgccagtg acgtttttga aacgcgctgc
     9421 tcatgtgcgt ggtaatcagt cctgtaggaa tcgcaatcac cgaataacca atcaaaataa
     9481 gcaccgacgc gacaatacgt cccagcggcg tatgcggcgt aatatcaccg taccccacgg
     9541 ttgtgactgt cactatcgcc caatacaccg aggcattaag cgtcgtgaag ccatatttcg
     9601 gtccttcaat aagatacatc agggcaccga aaataatcat cacgatcgca ataaatgaat
     9661 agaacagaat aagctgatga cgcgcgctaa taatggcgct ccagaatacg cgcagggatg
     9721 gcataaaacg tagcagttta agaatacgca gcacgcgaat cgctcgcata gcgcgccagg
     9781 caaacatata gttcaggcta atttccggcc atagccacat gacgtacagc ggcaaaatcg
     9841 tcaccagatc aataaatccc cagaaactaa aaacgtattt tgccggttcg ggccaactaa
     9901 acagtctgag caagtattca ccggtaaata tcagggtaac gcacagctcc agccagacaa
     9961 aaatatgcca ttcatcaaat gtcaggtgat attccgttcc tacgcctgat tcaacaaaaa
    10021 tgaccagtac gctaagcagc gcaaacagcg cgcataaccc ttcaaaacgg cgacttgagc
    10081 gcgtagtcaa atcgaacaga ttatgataaa gacgacggcg aaccgacgac aaagaaagtg
    10141 acacggtaac ctcacctaaa agaagggctg acgaattgtc agcccttgcg attataacgg
    10201 gtctacttta aggcaggaaa cggcatggcg aaaactccct tccaacaccg gtcgcgtttg
    10261 cgcgcattct ggcccggcta gcggacagcg tgtacggaac acgcagccgg aaggcgggtt
    10321 aatgggcgaa ggtaattcgc cctccagcaa ttgtatcttc ttatttcgct ccagatcggg
    10381 atcgggaatc ggtaccgccg acatcagcgc tttggtataa ggatgcagtg gattatggta
    10441 cacctcatca taggtgccca attctaccgc atgaccgaga tacatcacca ggacacgatc
    10501 ggatatgtgc tttacgaccg ccagatcgtg cgcaataaaa atcaacgaca gccccatctc
    10561 tcgctgtaac tgctggagca aattcaccac ctgcgcctga atagaaacgt ccagcgccga
    10621 caccggctca tcgcaaataa tgagcttagg ctccaggatc aacgcccggg cgataccgat
    10681 gcgctggcac tgccccccgg aaaactcatg gggataacgg ttgatgagat tcggcagcag
    10741 ccccactttc agcatcatgg ctttcacgcg gtcacgcacg tcctggcgcg aaagcttagg
    10801 atgataagtg cgcagcggtt cagcgataat ttcgccaatc gtcattcgcg ggttgagtga
    10861 cgccagcggg tcctggaaaa tcatctggat gtcgctgcgc acctcgcgcc actcatccgc
    10921 tttcatgccc aacagatctt ttcccagcca ggcgacttta ccgtctgtcg ccttcaccag
    10981 accaataatg gcgcgcgcaa acgtcgactt gccgcagccg gattccccca ccacgccaag
    11041 cgtttcgcct tcatacaggc gtagcgtaac gccgtccacc gctttcaggg ttttcggcgg
    11101 ttgccagaac cactgcttcc cttctttgat atcaaaatgt acttttagat cggcgatttc
    11161 gaggagaact ttacgttgtt caatcacagc attcatagca gttcctccac cggtttaaaa
    11221 caggcgcgca agcgaccagg actgaacgct tcaagtggcg gcgcattatt gcagatctcc
    11281 atcgcatgag gacaacgcgg ctggaacgga caacctttag gcaaacgcaa taaattggga
    11341 ggattgcccg gaatcgtcag catttccgcc ccctcgctat ccagacgcgg caccgcatta
    11401 agcaagccta tcgaatacgg atgaacgggc tgataaaaga catcgcgcgc cttaccgtat
    11461 tccatggtac gcccggcata cattaccagg accttatcgc aaatacccgc gaccacgccc
    11521 agatcgtggg taatcatgat aatggcggta ttaaattcgc gctttagctc attaagcaag
    11581 gtcataatct gcgcctgcac ggtaacatca agcgcggtgg taggctcatc ggcaataagc
    11641 agtttcggcc tgcacaacag cgccatcgca atcatcacac gttgacgcat tccgccggaa
    11701 aattcgtgcg ggtacatttt catccgtttg cgcgcttccg gtatttttac ggcatccagc
    11761 attctgacgg actcttcaaa agcttccgct ttgctcattc ctttatgcag catcaggact
    11821 tccattaact gctccccaac gcgcatataa ggatttagcg aggtcatcgg gtcctgaaaa
    11881 atcatcgaaa tctgttctgc gcgcagcgta ttcagttcgc gctcaggtag attaagaatt
    11941 tcacgtccgt taaaggtcgc ggaaccgccg attcgaccat tcgtcgccag cagtcccatt
    12001 aatgcgaacg ccgtttgcga tttccccgat ccagactcgc caacaatacc taacgtttct
    12061 ccagcgcgaa gcgtaaagtt cagatcgttg accgccgtca catcgccatc aggcgtagcg
    12121 aacgtaacac gaagatcgtt tacctccagc agtacattcg ccggttgcgg cgcctgagtt
    12181 gcggtttctg ataagctcat ggctgtactc cttaacgatc ttttgggtcg agggcatcac
    12241 gcaggccatc gccaataaag ttaaaacaga ataacgtcac cacgagaaag ccagccggaa
    12301 acagcagcag ccacggtaag acttccattg aatttgcgcc atcgctcaac aacgctcccc
    12361 aactgcttaa cggttcctgc gtcccaagcc ccaggaaact gaggaaagac tcaaacagaa
    12421 tcatgctggg caccagcaac gatgcataca ctaccactac gcccaggacg ttaggcacaa
    12481 tatggcggat cacaatgctg gcggtcgaca caccacccac ctgcgcggct tcgatgaact
    12541 ctttacgttt aagacttagg gtttggccac gcacgatacg cgccatatca agccaggaga
    12601 ccatgccgat ggcgacgaaa atcaacagaa tgttctgcca aaaaacgtca ccagcaaaat
    12661 cacaaagaac ataaacggga acgagttgag gatctccaac aaacgcatca tcacagaatc
    12721 aattttgccg cccagatacc cggacagcga gccatacagc gttccgacaa tgaccgccac
    12781 cagcgcggcg gcaatcccga ccatcaatga gatacgcccg ccgatggcaa cgcgcaccaa
    12841 cagatcgcgc ccggaagagt cagtgccgaa atagtggccg gacgccatat ccggcgcgct
    12901 ggacatcatg ccccagtcgg tatcgaaata ggtaaattgc gacagcatag gcgctactgt
    12961 cacgaatagg gctatcagaa acaggacaat aagactggcc accgccgcac ggttatgcat
    13021 aaagcgccga cgggcatctt gccaaaggct gcgaccttcc acctccagct tttcactgaa
    13081 attttccagc gtctcgctgt ttttcttact taacatcatc gcgagctcca gtatcaatag
    13141 cgaattttcg ggtcgataac ggcatagagc acatcgacaa tggcgttaaa caatatggtc
    13201 agcgccccga ctaaaatggt caaacttaac accagcgagt aatcgcggtt gagcgcgcca
    13261 ttaacgaaaa gctgcccaat gcccggtaag ccataaatcg tttcaatcac cattgagccg
    13321 gtaataatgc cgacaaaggc tggccccata taggataaaa ccggcagcag cgcaggtttt
    13381 aacgcatggc ggaagatgat tctgcgcatc ggtaatcctt ttgcccgcgc ggtacgaata
    13441 aagttcgaat gcagaacttc aatcattgag ccgcgcgtaa tacgagcgat gctggcaata
    13501 taggccagtg aaagcgcgac catcggcagg atcataaatt ttaacgcccc gccgttccag
    13561 ccgccgccaa gcagccattg caaggttatt gcaaagacca tcaccagtag cggcgctacc
    13621 acaaaactgg ggataacgac gccggtcatg gcaaatccca tcaccgtata atcccatcgc
    13681 gtattttgct ttagcgcggc aatcacgcca gcgctgacac caataatgac cgccagcaaa
    13741 aaagcggcgg cgccaagttt cgccgaaacg gggaagctgg cggcaaccag atcgttgacc
    13801 gtgtaatctt tatatttaaa cgatggtcca aaatcgccat gcgccagctg cttcaggtag
    13861 ctgaagtact gcgtcatgat gggatcgttc agatgatatt ttgcttcaat attggccagc
    13921 acttccggcg gcaatgcgcg ctcgccggta aaaggactcc ccggcgcgag gcgcatcata
    13981 aagaaagaga tggtaataag aataaacagc gtcggaatcg cttccagaca gcggcgtaaa
    14041 ataaatttca acattgcccg taccttctgg cctgtgcctt tacttcccgg acgtgacaaa
    14101 agatccgcca gggaaagtta tagtgcgatg aaaaaagaca ccatgggaca accgcagttg
    14161 tcccatgtct tgccattaat gtttgataat atataagttt ttcacataaa tattatccag
    14221 cgggtcttta ccggtatacc cgcccaccca gggtttcacc aggcgcgcgt taacgtagta
    14281 atacaccggc acaatagccg agtctttatc taactgctgc tccgctttag cgtagagttc
    14341 gctgcgctgc gtatcgtccg ccactttcag cgtgtcggca atcagcttat caaacgccgg
    14401 gctcttataa tgcgcggtgt tatttgaact gtcggacaac atggtattca ggaacgaggt
    14461 cggttcatta taatctgcgc accacccggc tctggcgaca tcaaaggtgc cctgatgacg
    14521 ggtatccagg aaggttttcc attcctgatt ctccagattc acattgacgc ccagattttt
    14581 cttccagata gacgccacgg caatagccag ttttttatgc agatcggagg tgttatacag
    14641 caggtcgaat gttaagggct tatccgccgt aaagccggct tcagccaaca atttcttcgc
    14701 ttcttcatta cgcttttgct gggaccattt gaaccactca ggctctacca gttttgcgcc
    14761 atcggtatac ggcggcgtgt agctataagc gggtaaatcg ccctgatttt taaccttatt
    14821 aacaataatg tcgcgatcta acgccagttt cagcgcggta cgcacgcgga catcgttaaa
    14881 cggcgctttt tgattattaa tttcgtaata ataggtacac aaataagggt ctacgcggac
    14941 ttcattcggg atctctttct tcagtttctg gaataattcg atcggcatat tgttataagt
    15001 catatcgatc tcgccgctgc ggtagcggtt aacatccgtc acctccgaag agataggcaa
    15061 ataagttacc tgattgatga cggttttgtc gttatcccag tattgcgggt tacgctccag
    15121 cacgatacgt tcgttcacca cccaattttt taacttataa gcgccgttag tgacaatatt
    15181 ggctggttgc gtccatttat cgccaaattt ttcgaccgct gatttcggta caggagacac
    15241 tgaagggtgg accaacaatt tgtagaaata aggcaccggc tcacttaagg tcactttaaa
    15301 ggtgtgatca tcaagcgctt ttacccccag atcggtggcg ggttttttac cggcgataat
    15361 gtcatcgata ttaacgatat gaccgtattg cagatagctg gcgtacggcg atgccgtatt
    15421 aggatcggcc aggcgttgcc agctataaac gaaatcatgg gcggtgacgg gcgtaccatc
    15481 tgaccatttc gcattttcac gtagatggaa tgtccagact ttaaaatctt tattttccca
    15541 tttttccgcg acgcccggtg aaggatgccc ctcgacatca ctaattaata agccttcaaa
    15601 gagatcacgg ctgacgttcg attccggcac gccttcaatt ttatgcgggt cgagagactg
    15661 cacttctgat ccattattac gtaccaacgt ttgcttgtcg gctaactgaa caccggcggg
    15721 cacgtctgcc gcagtcgcgg cgctggcggc gatgaacgca gtgagtattc ccactgcaat
    15781 taaacttttt ttcgtgatgt tagacattgt gtttgtactc cactcattat aattactggt
    15841 ttttaccagc ctgtttaatc ccgtcagggc tcctgtacag cactggtggt gtactgccag
    15901 gtctgtcact gcttttgcta tcaccgactt tatttattct gacgattcgt tcgatcgctt
    15961 tcgtcgattc ggtatacgac gtacctgccc acgtcgcacg ttatttctga caaccatgta
    16021 aatgaaaata gttatcaaca atgtgaaatc ttctgcaaaa tgtttggccg aaaagtatca
    16081 aatgcgtttc tgaaccgcca attcattt
//
LOCUS       DAJVKX010000099        16093 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000099 DAJVKX010000000
VERSION     DAJVKX010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16093
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.099"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..107
                     /locus_tag="OPY25_003216"
     CDS             <1..107
                     /locus_tag="OPY25_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCS0928763.1"
                     /translation="MRSIDDSSLLNVLLSNIANNSLFHKISYIENKIK"
     gene            165..1587
                     /locus_tag="OPY25_003217"
                     /pseudo
     CDS             165..1587
                     /locus_tag="OPY25_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459711.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
     gene            1655..1807
                     /locus_tag="OPY25_003218"
     CDS             1655..1807
                     /locus_tag="OPY25_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928764.1"
                     /translation="MPWRDHVNPDGEVVSCCDNVIITGYHRLFVHPLWIFIMAFDVHS
                     RQSEAG"
     gene            1841..2632
                     /gene="nei"
                     /locus_tag="OPY25_003219"
     CDS             1841..2632
                     /gene="nei"
                     /locus_tag="OPY25_003219"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HCS0928765.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQL
                     VTRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKIIL
                     LYSASDIEMLTAEQLMTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLD
                     QSFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADE
                     NKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCAHCQK"
     gene            complement(2687..3733)
                     /locus_tag="OPY25_003220"
     CDS             complement(2687..3733)
                     /locus_tag="OPY25_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCS0928766.1"
                     /translation="MPILQWFLLFLLSLLISLIFLYLHLPAAMLLGPMIAGIVLSLRG
                     STLQLPRGIFLAAQAILGCMIAQNLTGSILTTLALYWPVVLFVLLVTLLSSAVVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRL
                     ILGDSAATVSQQVVWFPPLSGNLLTTLLLAIVAGIAGRLMRIPSGTMLLPMLAGALLH
                     SQGIIEIELPEWLLAVAYMAIGWRIGLGFDRQVFFMALRPLPQILLSIFALMAICAAM
                     AWGMAYYMQIDFMTAYLATSPGGLDTVAAIAAGSSADMALIMAMQTLRLFSILLTGPA
                     VARFISTYAPKQPL"
     gene            complement(3870..5153)
                     /locus_tag="OPY25_003221"
     CDS             complement(3870..5153)
                     /locus_tag="OPY25_003221"
                     /EC_number="2.3.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HCS0928767.1"
                     /translation="MADTKAKITLTGDTAIELDVLKGTLGQDVIDIRSLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLYGEKPTQEEYD
                     EFRTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCETYEVNPVLER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMGLEHIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWNEMHTDGMKIARPRQLYTGYDKRDFKSALKR"
     gene            5254..5499
                     /locus_tag="OPY25_003222"
     CDS             5254..5499
                     /locus_tag="OPY25_003222"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928768.1"
                     /translation="MHQSTVTSLLFGSPLCERGDDLGTEQWAFAGNGLINFELAANQE
                     RSNPSNVTCLSLITVLKEWVNIIVLLHNLLTGERVTP"
     gene            5893..6297
                     /gene="sdhC"
                     /locus_tag="OPY25_003223"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             5893..6297
                     /gene="sdhC"
                     /locus_tag="OPY25_003223"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HCS0928769.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFI
                     AVGILLWLLGTSLSSPEGFQQAADIMDGFIVKFIMWGILTALAYHVIVGIRHMLMDFG
                     YLEETFEAGQRSAKISFVITVVLSLLAGVLVW"
     gene            6291..6638
                     /gene="sdhD"
                     /locus_tag="OPY25_003224"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             6291..6638
                     /gene="sdhD"
                     /locus_tag="OPY25_003224"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HCS0928770.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     FEAWTGFFSSAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLAVRLILQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            6638..8404
                     /gene="sdhA"
                     /locus_tag="OPY25_003225"
     CDS             6638..8404
                     /gene="sdhA"
                     /locus_tag="OPY25_003225"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HCS0928771.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETCEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMALRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMECY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEQGEDVVIPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGVLRDASESDVEGSLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPERDDANWLCHTLYQPQTESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            8421..9137
                     /gene="sdhB"
                     /locus_tag="OPY25_003226"
     CDS             8421..9137
                     /gene="sdhB"
                     /locus_tag="OPY25_003226"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HCS0928772.1"
                     /translation="MKLEFSIYRYNPDVDNAPRMQDYTLEGEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALTQSGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLEGMSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRSA"
     gene            9663..12464
                     /gene="sucA"
                     /locus_tag="OPY25_003227"
     CDS             9663..12464
                     /gene="sucA"
                     /locus_tag="OPY25_003227"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HCS0928773.1"
                     /translation="MQNSALKAWLDSSYLSGSNQSWIEQLYEDFLTDPDSVDANWRLT
                     FQQLPGTGVKPDQLHSKTREYFRRQALAGSRHSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWKQERVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLDAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRAAFSADEKKRFLNELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMVRHAGNSGTREVVLGMAHRGRLNVLINVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDIETEGGLVHLALAFNPSHLEIVSPVVMGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEADKVATLEDATEMVNL
                     YRDALDAGECVVKEWRPMNMHSFTWSPYLNHEWDEAYPNKVEMKRLQELAKRISTVPE
                     AIEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQTNGSTYTPLQHIHSGQGQFKVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSTLDELANGS
                     FQPAIGEIDELDPKAVKRVVMCSGKVYYDLLEQRRKNDQKDVAIVRIEQLYPFPHKAV
                     QEALQPYAHVHDFVWCQEEPLNQGAWYCSQHHFREVIPFGAALRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVD"
     gene            12479..13687
                     /gene="odhB"
                     /locus_tag="OPY25_003228"
     CDS             12479..13687
                     /gene="odhB"
                     /locus_tag="OPY25_003228"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HCS0928774.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEEEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLEASAIKGTGVGGRLTREDVEKHLAKGESKAPAV
                     EPAAQPALGARGEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYG
                     EVFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGL
                     VTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPI
                     INPPQSAILGMHAIKDRPMAVDGKVEILPMMYLALSYDHRLIDGRESVGFLVTIKELL
                     EDPTRLLLDV"
     gene            13829..14995
                     /gene="sucC"
                     /locus_tag="OPY25_003229"
     CDS             13829..14995
                     /gene="sucC"
                     /locus_tag="OPY25_003229"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HCS0928775.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIG
                     AVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK"
     gene            14995..15864
                     /gene="sucD"
                     /locus_tag="OPY25_003230"
     CDS             14995..15864
                     /gene="sucD"
                     /locus_tag="OPY25_003230"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HCS0928776.1"
                     /translation="MSVLINKDTNVICQGFTGSQGTFHSEQAIAYGTQMVGGVTPGKG
                     GTTHLGLPVFNTVREAVEATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILKLFQEDPQTEAIVMIGEIGGSAEEEA
                     AAYIKDHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKAIIK"
BASE COUNT         3998 a         3946 c         4427 g         3722 t
ORIGIN      
        1 tgatgagaag tattgatgac tcatcattgc tcaatgtgtt actttcaaat attgctaaca
       61 atagtctttt tcataaaatt tcttatattg aaaataagat taaataaaat atggatatga
      121 actttaaaaa atacaagacc gtaagctttg atatctttga tacattggtt agccggagga
      181 tttaccgtcc cagagatttg ttttcattaa tgcaatcaac tttagcaact gagaaatttt
      241 ttatatcagc gtacgagatt ggtattattg ataatttccc agagataaga gttcaggcgg
      301 aagtaagtgc cagagagaat agggtcaggc gttttggcgg cgagccggaa atacttatat
      361 ctgaaatata cgatgaaatt ttaaaaaagc atccgcagct ttcaccagcg acagtaaaaa
      421 agataatcga tctggaaata caaatggaga agattgtttt atataaaaat gcgcgtggaa
      481 gctgtttgtt tgaaaaggct attagtgatg gttgcaaagt cattttaatt agtgatatgt
      541 accttccatc agcaatatta aaggagttgt taacatcatg tggctatgat atcagtaaca
      601 ttccagttta ttcatctggc gaagagcggt actctaaaaa tagtggtaaa ttattttcaa
      661 tagtcaagaa aaatgaaaat gtagatattg catcgtggat acatgttggc gataatgttc
      721 atgctgatat tctgaatgct aaaaaactcg gcataaatac tctccatgct gattggtcag
      781 agtataatca tgggatatct aatcattgga aagctaaaga tattatgggt gaatctattt
      841 gtaagtcttt attacttaaa caagtgtctg ctttccatct actttaaaac ggcctgtgaa
      901 ggttttaaaa atatagcact tatcgatgta ggatggatgg gtaatattca atcagtattt
      961 gctcgttctt taggtgcgca atgggcagaa aaacaaatac atgggtttta tttggcaact
     1021 tttgctggcg ccaatgataa ccgatctatt tataataaga tgtttggtta tctaaccaac
     1081 tatggccatc cccacgataa gtgtgatctt ttcttatcag gaggggtgga aataatggag
     1141 ttcgctatgg ctgataatac tgggtcaaca attggctata aaaaaacgga taatggaata
     1201 attcctgtac gtgaagatag cagtggttct gaaattgagt atttaaaaaa agcggcaaga
     1261 ttgcaatcag ggattatttc tttttttgag tacgtcaaac cgctcataca aaaaggaaat
     1321 tatgcagcac ttagtagtgt tgtattgtca gaaccttttt ttgaattgat agccagaccc
     1381 tcaagcgctc aactggacgc cttatcttcc ctcacacatt cagagtccgc gggatctaac
     1441 gcagaaagaa tcgtgctagc caaaaaactg cctttaaagg ataaactttt tcccggagaa
     1501 aattatatca aagagttgaa tgccagttat tggaaagaag gctttaaaag gctcaacaga
     1561 aaaaaatttt gggcaaaata taactaagcg tcatttaatt tcggtaggca gacaatcatt
     1621 attaggcgct cgcccgacaa gggctgagtc gattatgccc tggcgcgatc acgttaaccc
     1681 tgacggggaa gtggtctcgt gctgcgataa tgttattatc actggatacc accgcctgtt
     1741 tgtccatccg ctgtggatat tcattatggc gttcgatgtg cattccagac agtcagaggc
     1801 ggggtagtcc attaatcaac tgttaacaaa ggatattatc atgcctgaag gcccggaaat
     1861 tcgtcgtgcg gcggataatc tggaggcggc aatcaaaggc aaacccttaa ccgatgtctg
     1921 gtttgccttt gcacagttaa aaccgtatga atcgcagctt accggtcaac ttgttacccg
     1981 gatagagacg cggggaaaag cgttattgac ccacttttca aatggcctga cgctctacag
     2041 ccacaaccaa ctctatggcg tatggcgggt gatcgacacc ggtgaaatac cgcagaccac
     2101 gcgtatatta cgcgtcaggc tacaaacggc ggataaaatt attctgcttt atagcgcgtc
     2161 tgatatcgaa atgctgacag cagagcagct catgacgcac ccttttttac agcgagtcgg
     2221 tccggatgtg ttggacgcgc gtcttactcc ggaagaggtt aaagctcgat tgctgtcgcc
     2281 gcgttttcgc aaccgacaat tttccgggct gttgctggat cagtcctttc tggcgggact
     2341 ggggaattat ctgcgcgttg aaatcctctg gcaggtagga ttaaccggac agcataaagc
     2401 gaaagatctc aacgaggcgc aactgaatgc gctttctcac gcgctgttgg atattccgcg
     2461 cctttcctac acgactcgcg gtcaggcgga tgagaacaag catcatggcg cactgtttcg
     2521 ctttaaggtt ttccaccgtg acggtgaagc gtgcgagcgg tgcggcggca ttattgaaaa
     2581 gacaacactt tcctcacgcc cgttttactg gtgcgcgcat tgccagaaat agccggaacc
     2641 gccatcggcg agcggctatt gtctgatggc gcgacgctta tcagccctac aaaggttgtt
     2701 tgggcgcata ggttgatata aaacgggcca ctgctggccc agttaacaga atgctgaaca
     2761 gccgtagggt ttgcattgcc atgatgagcg ccatatcggc actgcttcct gccgcgatcg
     2821 cggcaaccgt atccagaccc ccgggactgg tggcgagata agccgtcata aaatcaatct
     2881 gcatgtagta agccattccc cacgccatcg cggcgcaaat cgccatcagc gcgaaaattg
     2941 acaataagat ttgcggcaat ggccgcagcg ccataaaaaa cacctgtctg tcaaaaccca
     3001 gcccaatacg ccagcctatc gccatatacg ccacggccag cagccattcg ggtaattcaa
     3061 tttcaatgat gccttgcgaa tggagaagcg cgcctgccaa catggggagc agcatcgtgc
     3121 cggaagggat acgcatcagg cgaccggcaa tgcccgccac gatcgctaat agcagcgtcg
     3181 tcaataaatt accgctaagc ggcggaaacc agaccacctg ttggctgacc gttgccgcgc
     3241 tgtcgccgag tatcaggcgt gtcaccagca ccgccgcgcc agccacaaac agtacccgta
     3301 gatactgcat aaacgccacc aggcggatat ccgccccgta atcttgcgcc atcgctacca
     3361 ttgccgccgc gccgcccggc gaagaccccc atgcgccggt gttgccgggc agcgagctgt
     3421 aacgtaccag cagccagccg actaccgcgc tggaaagcag cgtcaccagc aacacaaaaa
     3481 gcacgaccgg ccagtagagg gcgagggtgg tcaatatcga accggttaga ttttgggcga
     3541 tcatacagcc gagaatcgcc tgcgcggcga gaaaaatacc gcgaggaagt tgtagcgtgc
     3601 tacctcgcaa actcaacacg atacccgcaa tcattggacc aagcagcatc gccgccggaa
     3661 ggtgcagata gagaaaaata agggaaatga gcagcgataa caggaacaac aaaaaccact
     3721 gcaaaatcgg cattccatgc tccctgaatg atatttagcg aaaccttaat taatcataga
     3781 gagtaacggg gtaagaataa aataatgagg ataagaaaaa agggaaaatg taccggatgg
     3841 cgagggttgc gtcgccatcc ggttgtcaat taacgcttca gcgccgattt aaaatcgcgt
     3901 ttatcgtagc cggtatacag ctgacgagga cgggcgattt tcatgccgtc agtgtgcatt
     3961 tcattccagt gtgcaatcca gccaacggta cgcgccatgg cgaagatcac ggtgaacata
     4021 gaggacggaa tgcccatcgc tttcagaatg atgccggagt agaagtctac gttcgggtac
     4081 agtttcttct cgatgaagta cgggtcgttg agcgcaatgt gctcaagccc catcgccact
     4141 tccagcagat cgtctttggt gcccagctct ttcagcactt cgtggcaggt ttcacgcatc
     4201 acggtggcgc gcggatcgta gtttttgtaa acacggtgac cgaagcccat caggcggaaa
     4261 gaatcattct tgtctttcgc acggcgaaca aattccggaa tgtgtttaac agagctgatt
     4321 tcttccagca ttttcagcgc ggcttcgttg gcgccgccgt gcgcgggtcc ccacagggag
     4381 gcgatcccgg cggcaatgca ggcgaacggg ttggcgccgc ttgaacctgc ggtacgtacc
     4441 gttgacgtag aggcgttctg ctcatggtca gcgtgcagga tcagaatacg gtccatcgcg
     4501 cgctccagta ccggattcac ttcataggtt tcacacggcg tggagaacat catgttcagg
     4561 aagttaccgg cgtaggaaag gtcgttgcgc ggataaacaa acggctgacc gattgaatat
     4621 ttgtaacaca tcgccgccat ggtcggcatt ttggacagca ggcggaacgc cgcgatttca
     4681 cggtggcgcg gattgttcac atccagcgag tcgtggtaga acgccgccag cgcgccagtg
     4741 atcccgcaca ttaccgccat cggatgtgag tcgcgacgga aagcatggaa caggcgagtg
     4801 atttgctcat ggatcatcgt atggcgggtg actgtcgttc tgaactcgtc atactcttcc
     4861 tgcgtcggtt tttcgccgta cagcaggatg taacagactt ccagatagtt ggaatcggta
     4921 gcaagctggt caatcgggaa accgcgatgc aacaaaatgc cttcgtcgcc gtcgatgaag
     4981 gtgattttag attcgcagga tgcggtagag gtgaaaccag ggtcaaaagt aaaaactcct
     5041 tttgaaccga gactacgaat atcaataaca tcttgaccga gtgtgccttt tagcacatcc
     5101 agttcaatag cagtgtcacc agtaagggtg atttttgcct ttgtatcagc catttacggt
     5161 ctccttagcg ccttattgct taagactgcc ggaactcaga cttgccttct ccacgtcatc
     5221 ttcctcgtcg ttagtgcagg gaaaattctg tgtatgcatc aatcaaccgt taccagtttg
     5281 ttatttggct cgccgctctg tgaaagaggg gatgacctgg gtacagagca atgggcgttt
     5341 gcaggtaacg gcttgattaa tttcgaatta gcagcaaatc aggaacgtag caatccgagt
     5401 aatgtaacct gtctatcact aataactgtc ctgaaagaat gggtcaatat cattgtactg
     5461 ttacataact tattaacagg tgaaagagtg accccataac ttttacgcat tatatgcttt
     5521 ttctggtgtt gtttgtaaca attttgttta atgtttgtca aatcagatga ttgaaaatta
     5581 aaaaaatgtt gttatcgtga cctgtgtcac tgttcaggat aaaacccgac aaactatatg
     5641 taggttaatt gtaatgattt tgtgaacgtc ctatactgcc gccaggtctc cggaataccc
     5701 tgcaatcccg agccacccag cgttgtaacg tgtcgtttta gctactggaa gcagtgtttt
     5761 acatgacgcg cagttataga aaggacgctg tctgacccgc acgcagaccg gaggaaggaa
     5821 atcccgtcgt ctttctggct acaggtagat tcacctctgt aaccgaagtc ttaagggaat
     5881 aataagaaca gcatgtgggc gttattcatg ataagaaatg tgaaaaaaca aagacctgtc
     5941 aatctggatc tacaaacgat tcggttcccc atcacagcga tagcgtccat tctccatcgc
     6001 gtatccggtg tgattacttt catcgccgtc ggcatactac tgtggctact gggcaccagc
     6061 ctctcttctc cggaaggatt ccagcaggcc gccgacatca tggacggctt catcgttaaa
     6121 tttatcatgt ggggcatcct taccgcgctg gcgtatcacg tcatcgtggg aattcgtcac
     6181 atgttaatgg attttggcta tctggaagaa acattcgaag cgggtcaacg ctctgccaaa
     6241 atctcttttg ttatcactgt cgtgctttca cttctcgcag gagtcctcgt atggtaagca
     6301 acgcctccgc attaggacgc aatggcgtac atgacttcat cctggtccgt gctaccgcta
     6361 tcgttctgac gttatacatc atctacatgg tgggtttttt cgccacgagc ggcgaactga
     6421 cctttgaagc ctggaccggt ttcttctcat cggccttcac caaagtcttc actctgctgg
     6481 cgcttttttc catcttaatt catgcctgga tcggcatgtg gcaggtgtta accgactacg
     6541 ttaaaccact ggcagtgcgt ctgatactgc aactcgttat tgttgttgcg ctggtggttt
     6601 acgtcatcta tggatttgtt gtggtgtggg gtgtgtaatg aaactgccag tcagagaatt
     6661 tgatgctgtt gtgattggtg ccggtggcgc aggtatgcgc gcggcgctgc aaatttccca
     6721 gagcggccaa acctgtgcgc tgctctcgaa agtcttcccg acccgttccc ataccgtttc
     6781 cgcgcagggc ggtatcaccg tggcgctcgg caatacccat gaagataact gggaatggca
     6841 catgtacgac accgtaaaag ggtcggacta cattggtgac caggatgcca tcgaatatat
     6901 gtgtaagacc ggaccggaag cgattctgga actggagcac atggggctac cgttctcccg
     6961 tcttgatgat ggacgtatct atcagcgccc gttcggcggc cagtcgaaaa actttggcgg
     7021 cgagcaggcg gcacgtaccg cggcggcggc tgaccgtacc ggtcacgcct tgctacatac
     7081 gctgtatcaa cagaatttga aaaaccacac cacgattttc tccgaatggt atgcgctgga
     7141 tctggtgaaa aaccaggatg gcgcggtggt ggggtgtacc gcactgtgca tcgaaacctg
     7201 tgaagtggtg tacttcaaag ctcgcgcgac ggtgctggcg accggcggcg caggccgtat
     7261 ctaccagtcc accaccaacg ctcatatcaa taccggtgac ggtgtcggta tggcgctgcg
     7321 tgccggtgtc ccggtgcagg atatggaaat gtggcagttc cacccgaccg gcatcgccgg
     7381 ggcgggcgtg ctggtgacag aaggctgccg cggcgaaggc ggttacctgc tgaacaaaca
     7441 cggcgagcgc tttatggagt gttatgcgcc gaacgccaaa gaccttgcgg gtcgtgacgt
     7501 ggtggcgcgt tccatcatga tcgaaatccg tgaaggtcgc ggctgtgatg gtccgtgggg
     7561 gccgcacgct aaactgaaac tggatcatct gggtaaagag gtgctggaat ctcgcctgcc
     7621 gggtatcctg gagctgtccc gcactttcgc tcacgtcgat ccggtgaaag agccgattcc
     7681 ggttatcccg acctgccact acatgatggg cggtattccg actaaagtga ccggtcaggc
     7741 gctgaccgtg aacgagcagg gcgaagacgt ggtgattccg gggctgtttg cggtaggcga
     7801 aatcgcctgt gtatcggttc acggcgccaa ccgtctgggc ggtaactcac tgctggatct
     7861 ggtggtcttt ggccgcgcgg cggggctgca tttacaggaa tccatcgccg agcagggcgt
     7921 gctgcgcgac gccagcgagt ctgacgttga aggttctctg gatcgcctga atcgctggaa
     7981 caataaccgc aatggcgaag atccggtggc tatccgcaaa gcattgcagg agtgtatgca
     8041 gcataacttc tccgtattcc gtgaaggcga cgcgatggcg aaagggcttg agcagttgaa
     8101 agtgatccgc gagcgtctga aaaacgcccg tctggatgac acgtccagcg agtttaatac
     8161 ccagcgtgtt gagtgtctgg agctggataa cctgatggaa accgcctacg ccactgccgt
     8221 atcagccaac ttccggacgg aaagccgcgg cgcgcatagc cgcttcgatt tcccggagcg
     8281 tgatgatgcc aactggttgt gtcataccct gtatcagccg caaacggaat ccatgacgcg
     8341 ccgaagcgtc aatatggaac cgaaactgcg tccggcgttc ccgccgaaga ttcgtactta
     8401 ttaattgcgg agacaggatg atgaaactcg aattttcgat ttatcgttat aacccggatg
     8461 tcgataacgc tccgcgtatg caggattaca ccctggaagg cgaagaaggg cgcgacatga
     8521 tgctgctgga tgcgttaatc cagcttaaag aaaaagatcc cagcctttct ttccgccgtt
     8581 cctgccgcga aggtgtgtgt ggttctgatg gtttgaatat gaacggtaag aatggtctgg
     8641 cctgtattac tcctatttcg gcgctgactc agtcgggtaa gaagattgtg attcgcccgc
     8701 tgcccggttt gccggtgatc cgcgatttgg tggtagacat ggggcaattc tacgcacaat
     8761 atgagaagat taagccttac ttattgaata atgggcaaaa tccaccggca cgtgagcatt
     8821 tacagatgcc ggagcagcgt gaaaaactcg atgggctgta tgaatgtatt ctttgcgcct
     8881 gttgctcaac atcctgcccg tcattctggt ggaacccgga taagtttatc ggtccggcgg
     8941 ggctgctcgc ggcgtatcga ttcctgatcg atagtcgtga taccgagact gacagtcgtc
     9001 tggaagggat gagcgatgca ttcagcgtat tccgctgtca cagcattatg aactgcgtca
     9061 gtgtatgtcc taagggactg aacccgacgc gcgctatcgg ccatattaag tcgatgctgt
     9121 tgcagcgtag cgcgtaagta gttgtagtgg ttgccggatg gcgacgtacc gtcttatccg
     9181 gcctacgggt tacgtattct gtaggcctga taagccaggt gccatcgggc aatagaagtg
     9241 caggaaacct ctaaaaactg ccatatgatt agtaataatc gagatgttca gagcgagaca
     9301 aggcgcggtc tgaacgaatc ttcgggagca tagttaacta tgtgaccgga gtgagcgaag
     9361 gccgcaacgc agtcgtagcc tgaacagcga agattattag acagttttta aaggttcctt
     9421 agcggacgca gatgacacga cagtccgcaa caagtgaacc ccggcacgca tacagcgtat
     9481 gcgtggttag tatccacggc gaaatactcg tcatagttca cgttgcatgt gcgttggctg
     9541 cacttgctca ccccagtcac ttactggatg taagctccca gggattcgca agcttgccgc
     9601 cttcctgaaa cgtgacctat ttagagtatt aaataagcag aaaagatgct taagggatca
     9661 cgatgcagaa cagcgctttg aaagcctggt tggactcttc ttacctctct ggttcgaatc
     9721 agagctggat agaacagctc tatgaagact tcttaaccga tcctgactcg gtagacgcta
     9781 actggcgttt gacgttccag cagttacctg gtaccggagt caaaccggat caactccatt
     9841 caaaaacacg tgaatatttc cggcggcagg cgttggctgg ctcacgtcac tcttctacga
     9901 tttccgaccc tgacaccaat gtgaagcagg ttaaagtcct gcagcttatc aacgcttatc
     9961 gtttccgtgg ccatcagcat gcaaacctcg atccgctggg actgtggaaa caagaacgcg
    10021 tggcggatct ggacccttct ttccatgatt tgaccgaggc cgatttccag gaaaccttca
    10081 atgtcggctc ctttgccagc ggcaaagaga cgatgaagct gggggagctg ctcgacgcgc
    10141 tcaaacagac ctactgcggc ccgattggcg ctgagtatat gcacatcacc agcaccgaag
    10201 agaaacgctg gatccaacag cgcatcgaat ccggtcgtgc ggcctttagc gctgacgaga
    10261 aaaaacgctt cctgaacgaa ctgaccgccg ctgaagggct ggaacgttat ctgggcgcca
    10321 aattcccggg tgcgaaacgt ttctcgctcg aggggggaga tgcgctgata cctatgctga
    10381 aagagatggt tcgccatgcg ggtaacagcg gcactcgcga agtggtgctg gggatggcgc
    10441 accgcggtcg tctgaacgtg ctgatcaacg tactgggtaa aaaaccgcag gatctgttcg
    10501 acgagtttgc cggtaaacat aaagaacatc tgggtaccgg cgacgtgaag tatcacatgg
    10561 gcttctcgtc agatatcgaa actgaaggcg gtctggttca cctggcgctg gcgtttaacc
    10621 catcgcatct ggaaattgtg agcccggtgg tgatgggctc cgtgcgcgcc cgtctggacc
    10681 gactggacga accgagcagt aataaagtgc tgccgatcac tattcacggc gacgccgcgg
    10741 tgaccggcca gggcgtggtt caggaaaccc tgaacatgtc gaaagcgcgc ggttacgaag
    10801 tgggcggtac ggtacgtatc gttatcaaca accaggtggg cttcactacc tctaacccac
    10861 tggatgcgcg ttcaacgcct tactgcaccg atatcggtaa aatggtccag gcgccgattt
    10921 tccacgtcaa tgcggacgat ccggaagccg tcgcttttgt gacccgtctg gcgctggact
    10981 tccgtaatac ctttaaacgc gatgtgttca tcgatctggt gtgctaccgc cgtcacggcc
    11041 acaacgaagc cgacgagcca agcgcaaccc agccgctgat gtaccagaaa atcaaaaagc
    11101 atccgacgcc gcgtaaaatc tacgccgaca agctggaagc tgataaggtc gcaacgctgg
    11161 aagatgccac cgaaatggtc aacctctatc gcgatgcgct ggatgcaggc gaatgcgtgg
    11221 tgaaagagtg gcgtccgatg aatatgcact cgttcacctg gtcgccgtat ctaaaccacg
    11281 aatgggatga agcatacccg aacaaggtag aaatgaagcg tctgcaggag ctggcaaaac
    11341 gtatcagcac cgtgccggaa gccattgaaa tgcagtctcg cgtggcgaaa atttatggcg
    11401 accgtcaggc aatggcggca ggcgagaaat tgtttgactg gggcggcgcg gaaaatctgg
    11461 cttacgccac gctggtcgat gaaggcattc cggtgcgcct gtccggggaa gactccggtc
    11521 gcggcacctt cttccatcgt catgcggtga tccacaacca gacgaacggc tcaacgtata
    11581 cgccgttgca gcatattcac agcggtcagg gacagtttaa agtctgggac tccgtgctgt
    11641 ctgaagaagc ggtactggct tttgaatacg gttatgccac ggcggaacca cgtaccctga
    11701 ctatctggga agcgcagttt ggcgattttg ccaacggcgc gcaggtagtg attgaccagt
    11761 tcatctcctc tggcgagcag aaatggggcc ggatgtgcgg tctggtgatg ctgttgccgc
    11821 acggctatga agggcagggg ccggagcact cctccgcgcg tctggaacgt tatctgcaac
    11881 tttgcgccga gcagaatatg caggtttgcg taccgtccac tccggcgcag gtctaccata
    11941 tgctgcgccg tcaggcgctg cgcgggatgc gtcgtccgct ggtggtgatg tcgccgaaat
    12001 cgctgctgcg tcacccgctg gcggtttcca cgcttgatga actggcgaac ggttccttcc
    12061 agccggccat tggcgaaatt gacgagctgg accctaaagc cgtaaaacgc gtggtaatgt
    12121 gttctggtaa ggtttattac gacctgctgg aacaacgtcg caaaaacgac cagaaagatg
    12181 tcgctatcgt gcgcatcgaa cagctctatc cgttcccgca taaagcggtg caggaagcgc
    12241 tgcaaccata cgctcacgtc catgattttg tctggtgcca ggaagagccg ctcaaccagg
    12301 gcgcatggta ctgcagtcag catcatttcc gtgaagtgat tccgtttggg gccgctctgc
    12361 gttatgcagg tcgcccggcc tccgcctctc cggcggtagg gtatatgtcc gttcaccaga
    12421 aacagcaaca agatctggtt aatgacgcgc tgaacgtcga ttaaataaag gataaataat
    12481 gagtagcgta gatattcttg ttcccgacct gcctgagtcc gtagcggacg cgaccgtcgc
    12541 cacctggcat aaaaaaccgg gcgatgcggt tgttcgtgac gaagtgctgg tagaaatcga
    12601 aactgacaaa gtggtactgg aagtaccggc atcagcggac ggcattctgg atgcggttct
    12661 ggaagaagag gggacgactg tcacctctcg ccagatcctg ggtcgcctgc gtgaaggcaa
    12721 cagcgcgggt aaagagacca gcgcgaaatc tgaagagaaa gcgtctacgc cggcacagcg
    12781 ccagcaggcg tcgctggaag aacaaaacaa cgatgcgctc agcccggcga tccgtcgcct
    12841 gctggctgaa cacaatctgg aagccagcgc cattaaaggc actggtgtgg gtgggcgtct
    12901 gacccgtgaa gatgtggaaa aacatctggc gaaaggcgag tctaaagcac ccgctgttga
    12961 acctgcagca caacccgctc tgggcgcgcg cggcgaaaaa cgcgtgccaa tgacccgcct
    13021 gcgtaagcgc gtggccgagc gtctgctgga agcgaaaaat tccaccgcca tgctgacgac
    13081 cttcaatgaa gtcaacatga agccgattat ggatttgcgt aagcagtatg gcgaagtgtt
    13141 tgaaaaacgt catggtatcc gcctgggctt tatgtccttc tacgtgaaag cggtagtgga
    13201 agcgctgaag cgttatccgg aagtgaacgc ctctatcgac ggcgatgacg tggtgtatca
    13261 caactacttt gatgtgagca tggcggtgtc tacgccgcgc ggcctggtca cgccggtcct
    13321 gcgtgacgtg gatacgctgg gcatggctga catcgagaaa aaaattaaag aactggctgt
    13381 caaaggccgc gacggcaagc tgaccgtaga agacctgacc ggcggtaact ttaccattac
    13441 caacggcggc gtattcggtt cgctgatgtc taccccgatc atcaacccgc cgcagagcgc
    13501 gattctggga atgcatgcta ttaaagacag gccgatggcg gtggatggca aggtggaaat
    13561 cctgccgatg atgtacctgg cgctctctta cgatcatcgc ctgatcgatg gtcgcgaatc
    13621 cgtgggcttc ctggtcacca tcaaagagtt gctggaagat ccgacccgtc tgctgttgga
    13681 cgtgtagtca gcaagagcat cacctgctac ctgtaggccg gataaggcgt tcacgccgcc
    13741 atccggcgat ggtgtaatgc ctgatggcgc gcagctttca ggcctacagg tctaaagata
    13801 acgattacct gaaggatgga cagaacacat gaacttacat gaatatcagg caaaacaact
    13861 ttttgcccgc tatggcttac cggcgccggt gggttatgcc tgtactactc cgcgtgaagc
    13921 cgaagaagcc gcgtctaaaa tcggtgccgg cccgtgggta gtgaaatgtc aggttcacgc
    13981 tggcggccgc ggcaaagcgg gcggtgtgaa ggtagtaaaa agcaaagaag agattcgcgc
    14041 ctttgcggaa aactggctgg gcaaacgtct ggtgacctat caaacagacg ctaatggcca
    14101 accggtaaac cagattctgg ttgaagcggc gaccgacatc ggcaaagaac tgtacctcgg
    14161 cgcggtggtt gaccgtagtt ctcgtcgcgt ggtctttatg gcgtctaccg aaggtggcgt
    14221 agagatcgaa aaagttgcgg aggaaacccc gcatctgatc cataaagtcg cgctcgatcc
    14281 gctgaccggc ccgatgccgt atcagggacg ggaactggcg ttcaaattgg gtctggaagg
    14341 taaactggtg cagcagttca ccaaaatctt tatgggcctg gcaaccattt ttcttgagcg
    14401 cgacctggcg ctaatcgaaa ttaatccgct ggtgatcact aagcagggcg atctgatttg
    14461 cctcgacggc aagctgggcg ctgacggcaa cgcgctgttc cgccagccgg atctgcgcga
    14521 aatgcgcgac cagtctcagg aagacccgcg tgaagcgcag gcggcacagt gggaactgaa
    14581 ctacgtcgcg ctggacggca acatcggttg catggtgaac ggcgcgggcc tggcgatggg
    14641 caccatggac atcgttaagc tgcatggcgg cgaaccggct aacttccttg acgtaggcgg
    14701 cggcgcaacc aaagagcgcg tcaccgaagc gtttaaaatt atcctctcgg atgacaacgt
    14761 gaaagcggtt ctggttaaca tcttcggcgg tatcgtccgt tgtgacctga ttgccgacgg
    14821 tatcatcggc gcggtggaag aagtgggcgt gaacgttccg gtggtggtgc gtctggaagg
    14881 caacaacgcc gaactcggcg cgaagaaact ggctgacagt ggcctgaata ttattgcagc
    14941 gaaaagtctg acggatgcag ctcagcaggt tgttgccgca gtggagggga aataatgtcc
    15001 gttttaatta ataaagatac caacgttatc tgccagggct tcaccggtag ccaggggact
    15061 ttccactccg aacaggcgat tgcttacggt acgcaaatgg tcggcggcgt aacgccgggc
    15121 aaaggcggca ccacgcatct gggtctgccg gtgttcaaca ccgtgcgcga agcggtagaa
    15181 gctaccggtg cgaccgcatc cgttatctac gtcccggcgc cgttctgcaa agactccatt
    15241 ctggaagcga tcgacgcagg catcaaactg attatcacca tcaccgaagg tattccgacg
    15301 ctggatatgc tgaccgtgaa agtgaagctg gacgaagcgg gcgtacgcat gatcggcccg
    15361 aactgcccag gtgtgatcac cccgggcgaa tgcaaaatcg gcatcatgcc gggtcacatt
    15421 cataagccgg gtaaagtggg tatcgtttcc cgttccggca cgctgaccta tgaagcggtt
    15481 aagcagacca ccgactacgg tttcggccag tccacctgcg tgggtatcgg cggcgacccg
    15541 attccgggct ctaacttcat cgacattctg aaactgttcc aggaagatcc gcagactgaa
    15601 gcgatcgtga tgatcggcga gatcggcggc agcgcggaag aagaagcggc ggcttatatt
    15661 aaagaccacg tgaccaagcc ggttgttggc tatatcgcgg gcgttaccgc gccgaaaggc
    15721 aaacgtatgg gccacgctgg cgccatcatt gccggtggta aaggtaccgc tgatgagaaa
    15781 ttcgctgctc tggaagcggc tggcgtgaag acggttcgca gcctggccga tatcggcgaa
    15841 gcgctgaaag caattataaa ataaaaactc gctgttcctg cgggaacaga taaatgtccg
    15901 ttttcgacat ggttggccac ctttacggtg gcctttttta tggttttatt gtttgtggca
    15961 aagtacgggt gaagcatccg ggatataaaa ttattggctt tgtaaatatt gaggtatagg
    16021 aaaatgatga ctcattaaaa aaacatggtg gagtctgaaa ataattgata ataaccgtct
    16081 ggcagcggca gta
//
LOCUS       DAJVKX010000100        16009 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.100, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000100 DAJVKX010000000
VERSION     DAJVKX010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16009
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.100"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(25..3549)
                     /gene="nifJ"
                     /locus_tag="OPY25_003231"
     CDS             complement(25..3549)
                     /gene="nifJ"
                     /locus_tag="OPY25_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCS0928777.1"
                     /translation="MQTIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEGGAIAAVHGALQTGSLSTSFTSSQGLLLMIPTLYKLAGQLTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAASVQEAQDFALIAHRATLKSR
                     VPFIHFFDGFRTSHEINKIIPLTDETILNLMPQAEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEEAMKAFGDATGRQYQPFEYYGHPQAERVIIMMGSAL
                     GTCEEVVDELLIRGEKVGVLKVRLFRPFSAKHLLQALPETVRAIAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRTIGGRYGLSSKEFGPACVLAVFNELSRAKPKPRF
                     TVGIYDDVTNLSLPLPENTLPGSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEKPIRSAYLIAQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVVNAAKIARECGLGARINTVMQMAF
                     FHLTHILPGDSALVELQGAIAKSYSSKGQDLVERNWQALALAQESLAEVPLQAVNPHS
                     AHRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     VWKEELCTQCNHCVAACPHSAIRAKVVSPQAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPQIKAINMMSRLEHVEEEKVNYDFFLDLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWTNSLFEDNAEFGLGFRLSVDQHRARVMRLLAQFADRIPAELND
                     ALHAEATPDVRREQVAALRQHLKSVAGAEELLKDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAWPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKPPLALDSRPPSDALAETLLNEQRFRRLNAQQPEVAEQL
                     WRDAALDLQKRYDFLALLAGKAEKPSAD"
     gene            complement(3610..3921)
                     /locus_tag="OPY25_003232"
     CDS             complement(3610..3921)
                     /locus_tag="OPY25_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
                     /protein_id="HCS0928778.1"
                     /translation="MAKHAPQLPAEQVRYCKPTIITRHIPPKTLRAFLSPLFIHPNDT
                     ALNNRQQKLTRREAKRAFMRFINIYWQFFTSFRQEIAILLPPGTQKRKWGLKGFAKIK
                     G"
     gene            3825..4091
                     /locus_tag="OPY25_003233"
     CDS             3825..4091
                     /locus_tag="OPY25_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HCS0928779.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVSPGMKAAMSSAGEA
                     NCAMIGGSLSAARQLDGSVIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            complement(4135..4545)
                     /gene="hslJ"
                     /locus_tag="OPY25_003234"
     CDS             complement(4135..4545)
                     /gene="hslJ"
                     /locus_tag="OPY25_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HCS0928780.1"
                     /translation="MKKIVTLVALSIIMTGCVSSGKVSVKREQLEHHRFVLESVNGKT
                     VTGPELSFGEDMTVSGKMCNQFTGEGKLSDGELKVKNLAMTRMMCADPQLNALDGTLS
                     ELFSKGAQVDLTANQLTLATAETTLMYKLADLAH"
     gene            complement(4656..5645)
                     /gene="ldhA"
                     /locus_tag="OPY25_003235"
     CDS             complement(4656..5645)
                     /gene="ldhA"
                     /locus_tag="OPY25_003235"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HCS0928781.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNEAFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMHGKTAGVIGTGKIGVAAL
                     RILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHA
                     AFDQMKNGVMIINTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALISISETTLQNLSQLEKGEACPNALF"
     gene            5912..8548
                     /locus_tag="OPY25_003236"
     CDS             5912..8548
                     /locus_tag="OPY25_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HCS0928782.1"
                     /translation="MKGKYKAALALLLLLILVPLTLLMTLGLWVPTLAGIWLPVGTRI
                     ALEQSPRLTRHGLVIPDLRYLVNDCSLAHITQAELTHPSRWLLNIKSLKLDAACLAKL
                     PASEASPAAPRTLAQWQSMLPNTWINIDNVILAPWPEWQGKLAISMTPVIQQIRYQGE
                     KVKFQGQLRGQALTVSQLEIAALANQPPVSLAGEFMLPLVPDGLPVSGHAAATLRLPQ
                     EPSLVDAELEWRDNAGQLIVMARGNPDPILDLPWAVTRQRLTVSDGRWNWPYQGFPLS
                     GRLAFNIDNWQAGPDNARVSGRLNILTQGDAGKANAVLTIGPGKLSMDSSEMPLQLTG
                     EAKQKDLIFYAVLPAMFRGSLADPQLTFAPGALLRSRGRVIDALDIDEIRWPLAGVKV
                     TPRGVDGRLQAILRAHENEMGDFVLHLDGLANDFLPDAGRWRWRYWGQGSFTPMRARW
                     DIAGQGEWHDNTIRLTSLSTGFDQLHYGAMTVTSPRLALDKPIVWVRDATTPSLQGAL
                     SLEAGKTVFTSGSVLPPSTLNFSVEGREPTLFQFKGDLRAGAIGPVRLNGRWDGERLR
                     GQAWWPKQSLIVFQPLLPPDWKMTLREGSLYAQVAFSAAQGQGFEAGGHGVLKGGSAW
                     MPDNKINGVDFILPFRFHNGAWQLGTRGPVSLRIAGIVNQVTAKNITADLQGGYPWSE
                     SNPLLLSDVSVDVLGGQIIMKQLRMPQHDPALLRVQNISSSELISAINPKQFAMSGPV
                     SGALPLWLNNEKWIIKDGWLTNPGPMTLRIDKDTADAVVKDNVTAGSAINWLRYMEIT
                     HSWTKINVDNLGVLTMQAAITGKSRVDGKTAIVNLNYTHEENVFTLWRSLRFGDNLQA
                     WLEQNTALPQPPCRKDKDCEDK"
     gene            8548..8739
                     /locus_tag="OPY25_003237"
     CDS             8548..8739
                     /locus_tag="OPY25_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HCS0928783.1"
                     /translation="MKMSIAMLSALASFIVVGCTPRIEVAAPEQPITINMNVKIEHEI
                     HIKVDKDVEELLKSRSDLF"
     gene            8747..9070
                     /locus_tag="OPY25_003238"
     CDS             8747..9070
                     /locus_tag="OPY25_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HCS0928784.1"
                     /translation="MKKYLILWVLTLSLLTPSVWALTLDEARTQGRVGETLNGYLVAL
                     KNDAETQKLVLDINHARRASYQQLADSNHLPVDEVAKMAGQKLVKRARPGEYVQGING
                     KWMRK"
     gene            9213..9662
                     /locus_tag="OPY25_003239"
     CDS             9213..9662
                     /locus_tag="OPY25_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GFA family protein"
                     /protein_id="HCS0928785.1"
                     /translation="MTSEKLSAACHCGSVVFTVQLSDGFHTARRCNCSFCRMRGAVAV
                     SAPLSGIKVLKGQDKLTEYRFNTGKAVHFFCSVCGIYTFHQRRSNPDQYGVNVACIEN
                     VSPFDFACVEVNDGVTHPSDGGSSGVVGYLRYEPKKSPPVETGGKNI"
     gene            complement(9659..10264)
                     /gene="azoR"
                     /locus_tag="OPY25_003240"
     CDS             complement(9659..10264)
                     /gene="azoR"
                     /locus_tag="OPY25_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCS0928786.1"
                     /translation="MSKVLVLKSSILAGYSQSGQLTDYFIEQWREKHVADEITVRDLA
                     ANPVPVLDGELVGAMRPGDAPLTPRQQDALALSDELIAELKAHDVIVIAAPMYNFNIP
                     TQLKNYFDLIARAGITFRYTEKGPEGLVTGKRAVVLSSRGGIHKDTPTDLIAPYLKVF
                     LGFIGITDVNFVFAEGIAYGPEVAAKAQADAKAAIDSVVAA"
     gene            10465..14367
                     /gene="hrpA"
                     /locus_tag="OPY25_003241"
     CDS             10465..14367
                     /gene="hrpA"
                     /locus_tag="OPY25_003241"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460600.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HCS0928787.1"
                     /translation="MTEQSTLTLQVLQQRLDALMLRDKQRFSRRLHGVKKVKNPDAQQ
                     AIFQTMAKEIEQAATQVALREAARPSITYPQNLPVSQKKQDILEAVRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELQTEPGGCIGYKVRF
                     SDHVSSNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKVIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELGRESPGDILIFMSGEREIRDTADALNKLNLRHTEVLPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITADEQQTAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPVDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNQFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHV
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWTMVAELVETSRLWGR
                     IAARIEPEWVEPVAQHLIKRSYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDDTLFEF
                     YDQRISHDVISARHFDSWWKKISRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVDESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVTPLELPLLDALERELRRMTGVTVDREDWHWDQVPEHLKIT
                     FRVVNDKNKKLQEGRSLAELKNALKGKVQETLSAVADDGIEQSGLHIWSFGELPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQQQAMWCGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCIACGVDKLIDANGGPVWSEAGFTALHEKVRAELN
                     DTVVDIAKQVERILTTVFNINKRLKGRVDMSMALGLSDIKAQMSGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDREQMLKVESVQQAWQQWINKLPPARREDDDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMDQITA"
     gene            14431..15231
                     /locus_tag="OPY25_003242"
     CDS             14431..15231
                     /locus_tag="OPY25_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCS0928788.1"
                     /translation="MNTTPFPALSAETLLAVNTVGQWLAQNDFSGEQPYSSDCVVLAG
                     NAVIPTIDAACRIAKAQGVPLLISGGIGHSTPFLYAVIARHPRYHTIRTTGRAEAAIL
                     ADIANQFWHIPAEKIWLEDRSTNCGENARFSCALIRQAKENINTAIVVQDPTMQRRTI
                     AAFRRVTNDDTDAPRWLSFPGFVPVLRHLNGGTRFANVEEGIWTVERYLSLIAGELPR
                     LRDDETGYGPRGKDFIIHVDIPRDIEKAWQVLQADTTLRSALEQRALR"
     gene            15348..15878
                     /gene="cybB"
                     /locus_tag="OPY25_003243"
                     /pseudo
     CDS             15348..15878
                     /gene="cybB"
                     /locus_tag="OPY25_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460598.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
BASE COUNT         3748 a         4073 c         4392 g         3796 t
ORIGIN      
        1 ccaggttaat ccttagaatg ttttttaatc tgcgctgggt ttttccgctt ttcctgccag
       61 caaggcaaga aagtcatagc gtttttgcaa atccaatgcg gcatctcgcc ataattgttc
      121 agctacttca ggctgttgcg cattcaggcg acggaaacgc tgttcattaa gcaacgtttc
      181 cgctagggca tcagacggtg gccgagagtc cagcgccagc ggcggcttgc cttcatccgc
      241 acggcgggga tcaaagcggt ataacggcca gaaaccggtc gccgttaact ggcgcatctg
      301 gtcatggctt agcgccagat cgtagccatg ttcctcacag ggactatagg caatgatcag
      361 cgacggtcct ggccaggctt cggcctcctg gatggctttc accgtctggt ttaactgcgc
      421 gcccagcgaa atttgcgcga cataaacatg accatacatc atcatgctga cgccaagatc
      481 tttacgggct ttacgcttgc catgttcgcc aaacttagtg acggcgccaa gcggcgtcgc
      541 cttcgacgcc tggccgccag tattggaata acactgcgta tccagaacca gaatattgac
      601 attctccgtc aggcttaaca catggtctaa accgccaaag ccgatgtcgt atgcccaacc
      661 atcgccgcca atcagccaga ttgatttttc taccagcgca tcagcatctt ttaacagttc
      721 ctctgcgccc gcaaccgatt tcagatgttg gcgtaatgcg gcgacctgtt cacgccgaac
      781 gtcaggcgtt gcttcggcat gcagcgcatc gtttaattcc gccggaatgc gatcggcgaa
      841 ttgcgccagt aaacgcatga cgcgcgcccg gtgctgatcc acactcagac ggaaaccgag
      901 gccaaattcc gcgttatctt caaatagcga attcgtccac gccgggccgc gtccgttggc
      961 atcggtggta taaggcgtag agggtaagtt accgccgtaa atagaggaac accccgtggc
     1021 gttagcgatt aacattctgt cgccatataa ctgagtcagc agtttaatat acggcgtttc
     1081 accgcagccg gaacaggcgc cggaatattc aaacagcggc gtaatgagct gcgatgtgcg
     1141 gatatcaatc cgttccagtt tgctgcgatc gatttccggc aagtcgagga agaagtcata
     1201 attcactttc tcttcttcca catgctcaag gcgcgacatc atgttaatcg ccttgatctg
     1261 tggattttgc cgatctttag ccgggcagac ctctacgcat aaattacagc cagtacagtc
     1321 ttccggcgcg acctgcagca catatttctg gccgcgcata tcgcgggact tcacgtccag
     1381 cgaatgcaga ctggctggcg cgttctccat cgcctgcggg gaaacgactt tcgcacgaat
     1441 cgccgagtga gggcaggcgg cgacgcagtg attacattgt gtacacagtt cctctttcca
     1501 gacaggaatc tcttcggcga tattgcgttt ttcccagcgg gtggtgccca ttggccatgt
     1561 tccgtccggc ggcagcgcgg aaacaggcag tgcgtcgccg aggcccgcca acatggcggc
     1621 ggtaacggtt ttcacgaaat ccggcgcggc gtcggagacg accggcgggc gatgcgcgct
     1681 gtgtggatta accgcctgca acggcacttc cgccagcgat tcctgcgcca gagccaatgc
     1741 ctgccagtta cgctcaacca gatcctgacc tttgctgcta tagcttttgg caatcgcgcc
     1801 ctgcagctca accagagcgc tatcgcccgg aagaatatgc gtcaggtgga agaacgccat
     1861 ttgcatgacg gtattgatgc gggcgcccag tccacattcg cgggcgattt tcgccgcgtt
     1921 gaccacgtaa aaacgcgcct ttttctgatt caataccgcc tgaacttctt gcggcagacg
     1981 cgaccagacc tcgtcggcgc tgtacggcgt attaagcaga aagataccgc ctggcttcag
     2041 acgctccgcc atctgatatt tatcgataaa ctgtaattga tggcagccga caaaatccgc
     2101 ctgagcaatt aagtaagcgg aacgaatggg tttttcgctg acgcgcaggt gcgataccgt
     2161 gagtccgcca gcttttttag agtcataaac gaaataacct tgcgcatacc acggcgtaga
     2221 attaccgata attttaatat tatttttcgt ggcggatacg ctgccgtcgc ttcccagacc
     2281 gtaaaataac gcttccagtt tagcgctgcc gggcagggta ttttccggta atggcagcga
     2341 gagattagtg acgtcatcat aaatgcccac cgtaaaccgt ggcttgggtt tcgcgcggct
     2401 gagttcatta aagaccgcca gtacgcacgc cgggccgaac tctttggatg atagcccata
     2461 acggccgcca atggtgcgcg gcaatgtttc gcgctcgcca ttattaaagg cttccgccag
     2521 tgcggtcatc acgtccagat aaagcggctc ggcctgggcg ccaggctctt tggtgcgatc
     2581 cagcacggcg atagcgcgaa cggtttccgg taatgcttgt aacaaatgtt tggcggagaa
     2641 ggggcggaac agacggactt tcagaacgcc gaccttttct ccgcgtatca gtagctcgtc
     2701 cacgacctct tcgcaggtgc cgagggcgga gcccatcata atgatgaccc gttcagcctg
     2761 gggatgacca taatattcaa atggctggta ctggcggcct gtagcatcgc caaatgcctt
     2821 catcgcctct tcaacatgat cataaacggc gttgtaccac gggttggtcg cttcgcgaga
     2881 ctggaagtag gtatccggat tcgcagaagt tccacgaatc accggatgct ccggattcag
     2941 cgcgcgggcg cggtgagcgt cgatctccgc ctgcggcatc aggttcagaa tggtttcatc
     3001 cgttagcggt ataattttgt tgatttcatg cgatgtacgg aagccatcaa aaaaatgaat
     3061 aaacggaacg cggcttttca gcgtagccct gtgcgcgatc agcgcaaaat cctgcgcttc
     3121 ctgaacgctg gcggcgcata acatcgcgca gcctgtctgg cggaccgcca tcacatcgga
     3181 atggtcgcca aaaatagaaa gcgcgtgtgt ggcgacggtg cgtgcggcaa cgtgcagtac
     3241 aaacggcgtg agctgccccg ccagtttata cagcgttggg atcatcagca gcagcccctg
     3301 cgatgatgta aatgacgtag aaagcgaacc ggtttgtaac gcaccgtgaa cggcggcgat
     3361 cgcaccgcct tccgactgca tctctaccac acgcggcgta tcgccccaga catttttaag
     3421 cccattgccg gcccaggcat ccgcttgttc agccattgtt gaactgggcg taatcgggta
     3481 aatggcgata acctcgctgg tacggaacgc caccgacgct actgcgccat taccgtcaat
     3541 cgtttgcata tgacaccctt acattgcgca aaaaagaggg acacgcataa tcgtgagcgt
     3601 atcctgtagt tatcctttta ttttagcaaa gcccttcaag ccccattttc gcttttgtgt
     3661 ccctggcggg aggagaatgg cgatttcttg ccgaaaagac gtaaaaaatt gccaataaat
     3721 gttaatgaag cgcataaatg cgcgctttgc ctctcgacgc gtcagtttct gctgcctatt
     3781 atttagggcg gtgtcgtttg gatgaataaa cagaggggag agaaatgcgc gcagcgtttt
     3841 gggtgggatg tgccgcgtta ttattgtcgg cttgcagtag cgaacctgtt cagcaggcaa
     3901 ctgcggcgca tgtttcgcca gggatgaaag cggcgatgtc cagcgccggc gaagcgaatt
     3961 gcgctatgat tggcggttcg ctttcagcgg cccggcagct tgatggttca gtaattggta
     4021 tgtgcgcgct acccaacggc aaacgttgta gcgaacagtc gcttgccgcc ggaagctgcg
     4081 ggagttatta agcgcggcgt ttcgcctgac gcgtataact tttcacttaa tggcttagtg
     4141 cgctaaatcc gccagtttat acattagcgt tgtttctgcc gtcgccagcg ttaattggtt
     4201 cgcagttaaa tcgacttgcg ctcctttgct gaagagctcg ctgagggtgc cgtccagcgc
     4261 attaagctgc ggatcggcgc acatcattcg ggtcatcgct aaatttttca cttttaattc
     4321 gccgtccgat agttttcctt cgccggtgaa ttgattgcac attttgccgg ataccgtcat
     4381 gtcctcgcca aagctgagct ccgggccggt gaccgtttta ccgtttacgc tttccagaac
     4441 aaagcggtgg tgctccagtt gctcgcgttt gacggacact tttccactgc tcacacaccc
     4501 tgtcattatg atgctcaggg cgaccagcgt gacgattttc ttcattgata ttctctgtaa
     4561 tctgatagtt aacactgact atagtaatga tatgaccgga tagatcttca ggggttatcc
     4621 gaaaatgctc ctctgagcgc aggggagcga caggattaga acagcgcgtt cgggcaggct
     4681 tcgcccttct caagctggct taagttttgt aacgtggttt cagagatgct gatcagcgct
     4741 tctgcggtca ggaatgcctg atgccccgta aacagtacgt tatggcaggc cgacagacgg
     4801 cggaaaacat catcctgaat aacatcgttt gacttgtcct caaagaacag gtcgcgttcg
     4861 ttttcataca catccatccc cagcgagccg attttctgat tcttcagagc ttcgatagcc
     4921 gcctgggaat caatcagcgc gccacgactg gtattaatga tcataacgcc atttttcatt
     4981 tgatcgaatg ccgcatggtt cagtaaatgg tagttttccg gcgtgagcgg gcagtgcagg
     5041 gaaatgacat ccgattcggc aaacaacgtt tgcagatcca catactcgac gccgaggtca
     5101 agcgcggcag tgctgggata gggatcaaac gccagtaaac gcattccaaa gcctttcagg
     5161 atacgcagcg cggcgacgcc gattttaccg gtaccaatga cgccagcggt ttttccgtgc
     5221 atggtaaagc cggtcagtcc ctcaagggaa aagttagcgt cgcgggtgcg ttgataagcg
     5281 cggtgaatac ggcggttcaa tgtcatcatc atgccaatcg catgttcagc gacggcttcc
     5341 ggagaataag ccggtacgcg caccacctgc aagccgagtt ctttagcggc atccaggtcg
     5401 acattattaa atccggcgca acgcagcgcg atgtatttca cgccgtgttt tttcagctct
     5461 tccagtaccg gtcggctccc gtcgtcattc acgaagatac aaactgcttc acatccattg
     5521 gcggttttcg ccgttttctc ggttagcaga aaatcaaaaa actccagttc aaaaccgaac
     5581 gcttcgttca cttgctgtag atatttcttg tcatactgtt tggtactata gacggcgagt
     5641 ttcatatgac cttctccagt gatgttagaa tcacacaaat atgcttaaaa ttatcttaca
     5701 aaaaatcaaa aataattgat agtcatacat atgatgaata attttaggtt atcattctcc
     5761 acgacgcctc aaatagtcgg agggcggccc tgcaacacgc ataacgtatc acccgtttgc
     5821 aacatgaact attaggctat gtacgggcaa tcatgccaaa ataaagagat agccgactga
     5881 atttttcgtt aaatcaggaa attaatggcc catgaagggt aaatataaag ccgcccttgc
     5941 gctactgtta ctgctgattc ttgtccctct gacgctactg atgaccctcg ggctgtgggt
     6001 tcccactctg gcgggaattt ggctacccgt cggtacccgt atcgctctgg aacaaagtcc
     6061 acgcctgaca cgtcatgggt tagtgattcc cgatcttcgc tatctggtca atgattgttc
     6121 gttagcgcat attacccagg cggaactgac gcatcccagc cgttggttgc tgaatattaa
     6181 aagcctcaaa ctggatgccg catgcctggc gaaactgccg gcttcggaag cttctcccgc
     6241 cgcgccgcgt acgctggcgc agtggcagtc aatgctgccc aatacctgga ttaacatcga
     6301 taatgtcatt ctcgcgccct ggccggaatg gcagggcaag ctggcgatct ccatgacgcc
     6361 ggtcattcag cagatacgtt atcagggcga aaaagtaaaa tttcaagggc agctacgcgg
     6421 tcaggcattg acggtgagcc aactggagat cgccgcgctg gccaaccagc ctcccgttag
     6481 cctggcgggg gagtttatgt tgccgctggt accggatggc ctgccggtca gcggtcatgc
     6541 ggcagcgacc ttgcgtctgc cgcaggaacc gtcgctggtg gatgcggaac tggagtggcg
     6601 tgataatgcc ggacagctca tcgtgatggc gcgaggtaat cctgatccga ttctcgatct
     6661 cccctgggcg gtaacgcgtc agcggcttac cgtcagcgat ggccgctgga actggccata
     6721 tcagggattc cccttgagcg gacgtctggc ttttaatatc gataactggc aagccgggcc
     6781 ggataatgcg cgagtcagcg gacgcctgaa tattctgacc cagggcgatg ccggtaaagc
     6841 gaacgcggta ctgactatcg gcccgggaaa actcagcatg gatagcagtg agatgcctct
     6901 acagcttacc ggcgaggcta aacagaagga tttaatcttt tatgccgtat tgcccgctat
     6961 gttccgcggc agtctggccg atccgcagct cacctttgca cctggcgcat tgctacgctc
     7021 acgcggacgg gtgattgatg cgttagatat tgatgaaatt cgttggccgc tggcgggcgt
     7081 taaggtaacg ccgcgcggcg ttgatggtcg attacaggct attttacggg cgcacgaaaa
     7141 tgagatgggc gatttcgttc ttcatcttga tggcctggcc aatgattttc tccctgatgc
     7201 tggtcgctgg cggtggcgct attgggggca aggaagcttt acgccaatgc gcgcccgctg
     7261 ggatattgcc ggacagggcg aatggcatga taacaccatc aggttgacca gtttgtccac
     7321 cggttttgat cagttgcact atggcgcaat gaccgtcaca tcgccaagac tggcgctgga
     7381 taaacctatt gtctgggttc gcgacgccac aacgccgtcg ctacagggcg cgctgtctct
     7441 ggaggcggga aaaaccgtat ttaccagcgg gagcgtgctg ccgccttcta cccttaattt
     7501 tagcgttgaa gggcgcgagc caaccctgtt ccagtttaaa ggcgaccttc gggcgggggc
     7561 gatagggccg gtacggctga acgggcgctg ggatggcgaa cgccttcgcg gacaggcctg
     7621 gtggccgaag cagtcgctta tcgttttcca gccgttgctt ccaccggact ggaaaatgac
     7681 gctgcgcgaa ggctcactgt atgcgcaggt ggctttttcc gctgcgcagg ggcagggatt
     7741 tgaagcaggt ggacacggcg tgttaaaggg cggtagcgcc tggatgccgg ataacaaaat
     7801 caacggcgtc gatttcattc tgccatttcg cttccacaac ggcgcgtggc aattggggac
     7861 gcgcgggccc gtctcgctgc gtattgccgg gatagtcaac caggtcacgg cgaaaaatat
     7921 caccgccgat ttacagggcg gttatccctg gagcgagtcg aatccattac tgctaagcga
     7981 tgtcagcgta gacgtgctgg gcggtcaaat tattatgaaa cagttgcgaa tgccgcagca
     8041 cgacccggcg cttttgcggg tgcaaaatat ttcatccagc gaattgatta gcgccataaa
     8101 tccaaagcaa ttcgccatgt ctggtccggt tagcggcgcg ctgccgctgt ggctgaacaa
     8161 tgaaaaatgg ataatcaaag atggctggct tacgaatcct gggccaatga cgttgcgtat
     8221 cgataaagat actgcggatg cggtggtgaa ggataatgtc acggcaggct cggcgattaa
     8281 ctggctacgt tatatggaga ttacgcattc gtggacaaaa attaacgttg ataacctggg
     8341 cgtactaacg atgcaggcgg ccattaccgg caaaagccgg gtagatggta aaaccgcgat
     8401 cgttaacttg aactataccc atgaagaaaa tgtgtttacg ctgtggcgca gtttgcgttt
     8461 tggcgacaat ttacaggcat ggcttgaaca aaatacagcg ttgccgcaac ctccttgccg
     8521 gaaagacaag gactgtgagg ataaataatg aaaatgagta ttgccatgct gtcagcgctt
     8581 gcgtcattta tcgtggtggg gtgcacgcca cgtattgaag tcgccgcgcc ggaacagccg
     8641 attaccatca acatgaatgt aaagatcgag catgaaatac atatcaaagt cgataaagac
     8701 gttgaagaac tcctgaaatc acgcagcgat ctattctgag gccataatga aaaagtattt
     8761 aatactatgg gtgctgacgc tgagcttgct cacaccttct gtgtgggcct taaccctgga
     8821 cgaagcgcgc acgcagggcc gggtcgggga aacgctgaat ggctatctgg tggccttaaa
     8881 gaatgatgcc gaaacccaga agctggtgct tgatatcaat catgcccgtc gcgccagtta
     8941 tcagcagtta gcggatagca atcatcttcc cgtggatgag gtggcgaaga tggcagggca
     9001 aaaactggtt aagcgcgcca ggccgggaga atatgtccag ggaattaatg gcaaatggat
     9061 gcgtaaataa ccgcttcccg acaatttttt taccgcaaaa tgcattttta tatgggtaat
     9121 ttttgaatac ggaggtcgta tttacattag gcgaaccgga aggctatttc tatactgtcg
     9181 actggtatca ctattcgcgt gagtaaccag gtatgacgtc tgaaaaatta tctgctgcct
     9241 gccattgtgg cagcgtcgtg tttaccgttc aacttagcga tggctttcat accgccaggc
     9301 gctgcaactg ttcgttttgc cggatgcgcg gagcggtggc agtgtctgcg ccgctatcgg
     9361 gtattaaagt gctaaaaggg caggataagc ttaccgaata tcgcttcaat acgggcaagg
     9421 cggtgcattt tttctgttcg gtatgcggga tatatacttt tcatcagcgc cgatccaatc
     9481 ccgatcaata tggggtcaat gtggcgtgca ttgaaaatgt gtcgcctttt gatttcgcct
     9541 gcgttgaagt caatgatggg gtaacgcatc ccagcgatgg cggcagtagc ggcgtggtag
     9601 gatatttgcg ctacgaacct aagaagtcac ctcccgtcga aacgggaggc aaaaatattt
     9661 aagcggccac gacgctgtca atcgcggctt ttgcatcggc ctgggcttta gctgccactt
     9721 ccggcccgta ggcgatgcct tcggcaaaga caaaattcac gtcggtgata ccgataaaac
     9781 caaggaacac tttcaggtaa ggcgcaatca aatccgtcgg ggtgtcttta tggataccgc
     9841 cgcggctgga gagaaccacc gcgcgtttgc cggttaccag accttccggg cctttttcgg
     9901 tatagcggaa agtgataccg gcgcgggcaa tcagatcaaa gtagtttttc agctgcgtcg
     9961 ggatattgaa attgtacatc ggtgccgcaa taacgatgac gtcgtgggct ttcagttcag
    10021 caatgagttc atcagacagc gccagagcgt cctgctgacg tggcgttaaa ggcgcatcgc
    10081 ccggacgcat cgcgcccacc agctcgccat ccagcaccgg aacagggttg gccgccagat
    10141 cgcggacagt aatttcatct gcgacgtgtt tttcgcgcca ttgttcaata aaatagtcag
    10201 tcaactgacc agactgagag taccctgcca gaatactgga tttaagaact aataccttgc
    10261 tcatgggtgt ttccttttat gtgtttgaag gggcgtgccc cgttgcttgt tgacacttta
    10321 ttcacaaata tgtcgcaggg atagcgcaat atatcgaacc ctttgttcga aattattgaa
    10381 caacacaaaa aaagccccaa tgtggtactc tatacctatc atttaaaacg attttaaaca
    10441 ggcagaatgc tgcccaagag ctttatgact gaacaatcta cgttgacgct tcaggtgtta
    10501 cagcagcggc tggatgcact gatgctgcgc gacaaacagc gcttttcgcg ccgcctgcat
    10561 ggcgtaaaga aagtaaaaaa tcctgatgcg caacaggcca ttttccagac gatggcgaaa
    10621 gaaattgaac aggctgcgac gcaggtcgct ctccgcgaag cggcgcgccc ctcaatcact
    10681 tatccgcaaa atctgcctgt tagccagaag aaacaggaca ttctggaagc ggtccgcgat
    10741 catcaggtgg tgatcgtggc aggggaaacc ggttccggta aaaccaccca gttgccgaaa
    10801 atttgtatgg aactgggacg cggaattaaa ggacttattg gacatactca accgcgtcgt
    10861 ctggcggcgc gcaccgtcgc taaccgcatt gccgaagagt tgcaaacgga gcctggcggc
    10921 tgcatcggct ataaagttcg tttcagcgat catgtcagta gcaacaccat ggtcaaactg
    10981 atgacggacg gtatcctgct ggcggaaatc cagcaggaca ggctattgat gcagtacgac
    11041 accatcatta ttgatgaagc gcatgaacgc agcctgaata ttgacttctt gctcggctat
    11101 ctgaaagagc ttctgccgcg tcgccccgat ctgaaagtga ttattacctc tgcgaccatc
    11161 gacccggaac gcttctcgcg ccactttaat aacgcgccga ttatcgaagt ctctggccga
    11221 acgtatcccg tagaagttcg ttatcgcccc atcgtggaag aggctgacga cactgaacgc
    11281 gatcagctac aggcaatttt cgacgctgtt gatgaactgg ggcgtgaaag tcctggcgat
    11341 atcctgattt ttatgagcgg agagcgggaa atccgcgata ccgccgatgc cctgaacaag
    11401 ctgaacttac ggcataccga agtgttgccg ctgtatgcac gcttgtcgaa cagcgaacag
    11461 aaccgcgttt tccagtcgca cagcggacgc cgtatcgtgc tggcgactaa cgtggcggaa
    11521 acctcgctga cggtgccggg tatcaaatat gtgatcgatc ctggcactgc gcgcatcagc
    11581 cgctacagct accgcactaa agtgcagcgc ctgccgattg aaccgatctc acaggcttcc
    11641 gccaatcagc gtaaagggcg ttgcggacgc gtatcggaag ggatctgcat tcgtctgtat
    11701 tcggaagatg actttttgtc acgcccggaa tttaccgacc cggaaattct acgtaccaac
    11761 ctggcgtcgg ttattttgca gatgaccgcc ctgggactgg gtgacatagc cgccttcccg
    11821 tttgtcgaag cgccggataa gcgcaatatt caggatggcg tgcgtttgtt ggaagagctg
    11881 ggggcgatta ccgccgacga acagcaaacg gcatataagc tgacgccgct gggccgacaa
    11941 ttatcccagt tgccggtcga cccgcgcctg gcgcgtatgg ttctggaagc gcaaaaacat
    12001 ggctgtgtgc gcgaagcgat gatcattact tccgcactct ctattcagga tccgcgcgag
    12061 cgcccagtgg ataagcagca ggcttccgat gagaaacacc ggcgtttcca tgataaggaa
    12121 tccgattttc tggcgtttgt taacctgtgg aattacctcg gcgagcaaca aaaggccctg
    12181 tcgtcgaatc aattccgccg tctgtgtcgc accgactatc tgaactattt acgcgtgcgt
    12241 gagtggcagg atatctatac ccaactgcgt caggtggtaa aagaactggg gattccggta
    12301 aacagcgaac ccgcagaata ccgggaaatt cacgttgcgt tgttaacggg gctgttgtcg
    12361 catatcggga tgaaagatgc cgataaacaa gagtacaccg gcgcgcgtaa cgcccgattc
    12421 tctattttcc ccggatccgg tttattcaaa aaaccgccga aatggacaat ggtcgccgag
    12481 ctggtggaaa ccagccgttt gtgggggcgc atcgctgccc gcattgagcc agaatgggtg
    12541 gaaccggtag cccagcacct gattaaacgt tcatatagcg aaccgcactg ggagcgggcg
    12601 caaggcgcgg tgatggcgac ggaaaaggtt actgtctacg gtctgccgat tgtcgccgcg
    12661 cgcaaggtga attatagcca gattgacccg gcgttgtgtc gcgagttgtt tatccgccat
    12721 gcgctggtgg agggggactg gcaaacccgt cacgccttct tccgtgagaa tctaaaattg
    12781 cgtgcggaag tcgaggaact tgagcacaaa tctcgccgcc gcgatatcct ggtggatgac
    12841 gataccctgt ttgagtttta tgaccagcgt attagccatg acgttatttc cgcccgccac
    12901 tttgatagtt ggtggaaaaa aatcagccgc gagacgccgg atctgctcaa ctttgaaaaa
    12961 agtatgctga ttaaagaagg cgcggaaaaa atcagcaaac tggattaccc gaatttctgg
    13021 caccagggca atctcaagct gcgtttgagc tatcagtttg aaccgggcgc ggatgctgac
    13081 ggcgtgaccg tccatattcc gttgccgcta cttaaccagg ttgacgagag cggttttgaa
    13141 tggcagatcc cagggctgcg ccgtgaatta gtgattgcgc tgattaaatc gttgccaaaa
    13201 ccggtacgtc gcaactttgt tccggcgcca aactatgctg aagcgttttt aggtcgcgta
    13261 acgccgctgg agctgccgct gctggacgct ctggagcgtg aactgcgccg gatgaccggc
    13321 gtcacggtcg atcgggaaga ctggcattgg gatcaggtgc ccgagcatct gaaaatcacg
    13381 tttcgcgtgg tgaatgacaa aaacaagaaa ctgcaggaag ggcgttcgct cgccgagctt
    13441 aaaaatgcgc tgaaaggcaa agtgcaggag acgctctcgg cggtagcgga tgacggcatc
    13501 gagcagagcg ggctgcatat ctggagtttc ggcgagctgc cggaaagcta cgaacagaaa
    13561 cgcggtaatt ataaagtgaa ggcgtggccg gcgttagtgg atgagcgtga cagcgtcgct
    13621 atcaaattgt ttgataatcc gctggaacaa caacaggcga tgtggtgcgg tttacgccgt
    13681 ctgctgttgc tcaatattcc ttcaccgatt aagtatctgc atgagaaatt gccgaataaa
    13741 gccaagctgg ggctgtactt taacccgtac ggcaaagtac tggagttgat tgatgactgt
    13801 atcgcctgcg gggtagataa gctgatagat gccaacggcg ggccggtgtg gagcgaagca
    13861 ggtttcaccg cgctgcacga aaaggtacgc gccgagctga atgatactgt ggtggatatc
    13921 gcgaagcagg ttgagcggat cctgacgacc gtattcaata tcaataagcg tctgaaaggg
    13981 cgggtggata tgagcatggc gttggggctt tccgatatca aggcgcagat gagcggtctg
    14041 gtataccgtg gttttgtgac tggcaacggc tttaaacgtc tcggcgatac gctgcgttat
    14101 ctgcaggcaa ttgaaaagcg gctggagaaa ctggctgtcg atccgcaccg cgatcgggag
    14161 caaatgctga aagtcgaaag cgtccagcag gcgtggcaac aatggataaa taaattgcct
    14221 ccagcgcgtc gcgaagatga tgatgttaaa gagatccgtt ggatgattga agaactgcgt
    14281 gtcagttatt tcgcccaaca gctcggtacg ccttatccta tttccgataa gcgtatttta
    14341 caggccatgg atcagattac ggcctaaaaa gccaggcgac gatatctttc aaagagatcc
    14401 ggtacaagtt cggaacaaaa aggaggaatt atgaatacaa cgccatttcc ggcgctctct
    14461 gcggaaacat tgctggcggt gaataccgtc ggacagtggc tggcgcaaaa tgatttttcc
    14521 ggcgaacaac cttattcgtc ggattgcgtc gtcctggcgg gcaatgcggt gatccccact
    14581 atcgacgcgg cctgtcgcat cgccaaagcg caaggcgttc ctttactgat tagcggcggt
    14641 ataggtcatt cgacgccgtt tttgtacgcc gtgattgccc ggcatccgcg ctaccatact
    14701 attcgcacaa ccggacgcgc tgaagccgct atcctcgcgg atatcgcgaa ccagttctgg
    14761 catattccgg ctgagaaaat ttggctggaa gatcggtcaa ctaattgcgg cgaaaatgcc
    14821 cgtttctcct gcgcactgat ccgtcaggcg aaagaaaaca ttaacacggc tatcgttgtg
    14881 caagacccca ccatgcagcg gcgcactatc gcggcgtttc ggcgcgtgac aaacgacgac
    14941 accgatgcgc cgcgctggct gagttttcct ggttttgttc cggtactgcg ccaccttaac
    15001 ggcggtacac gttttgccaa cgttgaagag ggcatctgga cggtggagcg ttatctgtct
    15061 ctgattgccg gcgagctgcc acgtttgcgt gacgatgaaa cagggtatgg accgcgtggt
    15121 aaagatttta tcattcacgt tgatatccca cgcgatattg aaaaggcatg gcaggtattg
    15181 caggcagata cgacgctgcg cagtgcgtta gaacagagag ctttacgcta aaaatcgccc
    15241 gtttgcgagg gtgaacgggc aagtgcgacc accatttcat aaatttgatg aattatttat
    15301 aaaagctggt tatgttgtcg ctttacggtt ttcattcagg acgcgctatg ggcaataagt
    15361 attccggcct gcaaattggt attcactggt tagtcttttt tctggttatt gtggcttacg
    15421 ccgcgatgga gctacgcggt tttgcgccgc gtagttatcg gccctagttt aatatgacgc
    15481 atgtttcatg tggtatcact attttgcttt taatggtggc gcgcttgatt attcggctga
    15541 aatatcccac gccgcccatt gttcctcgtc caaaaccgat gatgaccgga atggcgcatt
    15601 taggacatct ggtgatttac ctgttattta tcgtgctgcc tgttattggt ctggtcatga
    15661 tgtataaccg cggcaatccc tggttcgcat ttggcattac tatgccgcat gccgccgaag
    15721 ctaactttga acgcgtagat atgctgaaat cctggcacgt cacgctggcg aatctgggct
    15781 attttgttat tggacttcat gccatcgctg ctttgatgca tcactatttc tggaaagaca
    15841 atacgctgtt acggatgatg ccgcgtaagc gtaactgacc gtcctgtatg acgtttgcta
    15901 caggcggggt taactgcttt aggcaaacaa ggcatctatc agaggggatg gcgtattcca
    15961 tacagaaaac gcctgcgtct aaccaggacc cgtgacgcag gcgaaggag
//
LOCUS       DAJVKX010000101        15853 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.101, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000101 DAJVKX010000000
VERSION     DAJVKX010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15853
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.101"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            285..716
                     /locus_tag="OPY25_003244"
     CDS             285..716
                     /locus_tag="OPY25_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HCS0928789.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGAQ
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVEAGFAITKIALQS
                     KVAVADIDASTFDQIIQKAKAGCPVSQVLNAEITLDYQLNA"
     gene            complement(837..1748)
                     /gene="hlyE"
                     /locus_tag="OPY25_003245"
     CDS             complement(837..1748)
                     /gene="hlyE"
                     /locus_tag="OPY25_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin HlyE"
                     /protein_id="HCS0928790.1"
                     /translation="MTGIFAEQTVEVVKSAIETADGALDLYNKYLDQVIPWKTFDETI
                     KELSRFKQEYSQEASVLVGDIKVLLMDSQDKYFEATQTVYEWCGVVTQLLSAYILLFD
                     EYNEKKASAQKDILIRILDDGVKKLNEAQKSLLTSSQSFNNASGKLLALDSQLTNDFS
                     EKSSYFQSQVDRIRKEAYAGAAAGIVAGPFGLIISYSIAAGVIEGKLIPELNNRLKTV
                     QNFFTSLSATVKQANKDIDAAKLKLATEIAAIGEIKTETETTRFYVDYDDLMLSLLKG
                     AAKKMINTCNEYQQRHGKKTLFEVPDV"
     gene            complement(1879..2514)
                     /locus_tag="OPY25_003246"
     CDS             complement(1879..2514)
                     /locus_tag="OPY25_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928791.1"
                     /translation="MKLSVTLAFFGYMMVSSMAQASDINMWREPKPVVKEGKYYSLIM
                     DRGELQKAVKSSSNNYLFSEKGAGVKPLVLIGSPVEISEFMLQNKTRSIENHIKGLPD
                     IYMGVTKYKPKQRFTGLFPLQDILTQTVDQVSKFVPGTDITDAVGIPSDLKALQQAIL
                     AMKQKDKISKNILYVKFSYLPEDGMVKVGSKTVSFGRILEKMQQSNRTLRR"
     gene            3283..3612
                     /gene="hdeB"
                     /locus_tag="OPY25_003247"
     CDS             3283..3612
                     /gene="hdeB"
                     /locus_tag="OPY25_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HCS0928792.1"
                     /translation="MNKFSLATAGIIVAALVTSVSVNAATDTTKTNVTPKGMSCQEFV
                     DLNPQTMAPVAFWVLNEDEDFKGGDYVDFQETETTAVPLAVELCKKNPQSELSKIKDE
                     IKKELSK"
     gene            3755..4540
                     /locus_tag="OPY25_003248"
     CDS             3755..4540
                     /locus_tag="OPY25_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OBAP family protein"
                     /protein_id="HCS0928793.1"
                     /translation="MKILPLALFIIPFLAGCGANNTPPQTPIPGEKTSAKLRTLETGA
                     AAIQSRPPVDAISTYLDGFHFYSGDKNGQMEAHHYVTVLNEDVMQAVIYDGNTKNARL
                     MGVEYIISERLFKTLPPEEKKLWHSHQYEVKSGSLVAPGLPQVADKALMSKIVNTYGK
                     TWHTWHTDRDKTLPMGIPALMMGFTGDGQLDPALLADRDRRLGIDTQAIKRERQDLPE
                     HPVIKGANAWEQGEVIQLQRVQGSGEHGRGDTAHFGISEQSRQ"
     gene            4669..6453
                     /gene="treZ"
                     /locus_tag="OPY25_003249"
     CDS             4669..6453
                     /gene="treZ"
                     /locus_tag="OPY25_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="HCS0928794.1"
                     /translation="MSSKIFCKSWGAEYIAADVVRFRLWATGQQKVMLRLAGKDQEMQ
                     ASGDGWFTLDVSGVTPGTEYNFVLSDGMVLPDPASRAQKTDVNGPSYVIDPGSYAWRN
                     TGWKGSRWEQAVVYEMHTGTFTPEGTFHTAIAKLPYLAELGVTVIEVMPVAQFGGERG
                     WGYDGVLLYAPHSAYGTPDDFKAFIDTAHGYGLSVILDIVLNHFGPEGNYLPLLAPAF
                     FHKERMTPWGNGIAYDVDAVRRYIIEAPLYWLTEYHLDGLRFDAIDQIEDSSARHVLV
                     EIAQRIREDITDRPIHLTTEDSRNIISLHPRDQDGNAPLFTAEWNDDFHNAVHVFATG
                     ETQAYYNDFADAPEKHLARALAEGFAYQGEISPQTGEPRGVKSTGQPPVAFVDFIQNH
                     DQVGNRAQGDRLITLAGAERTKVLLATLLLSPHIPLLFMGEEYGESRPFLFFTDFHGD
                     LARAVREGRAKEFADHAGENVPDPNAPETFQRSKLNWKQQHSEEGKAWLAFTRELLLL
                     RQKHIVPLLSAARESSGTVLQTAPGFIAVSWRFPGGTLSLALNISATTVLLPDLPGKT
                     LFAWPNESTGSLSQHSLIVRLAQGESAS"
     gene            6450..8978
                     /gene="treY"
                     /locus_tag="OPY25_003250"
     CDS             6450..8978
                     /gene="treY"
                     /locus_tag="OPY25_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose synthase"
                     /protein_id="HCS0928795.1"
                     /translation="MIPTATYRLQFRNSMTFDRAAALVPYLKNLGISHLYASPIFTAT
                     KASTHGYDVTDANEIEPSIGGREGFERLVAELKAQGLGLIIDIVPNHMASSLENAWWR
                     DVLEYGKESRYARHFDIDWSRRLTLPFLGDTFDAVLGNGEIAIKPDPVTGKPTFAYYD
                     NYYPLAPATWQGREAEILALTDKAAIADLHERQPWKLMSWRDAARSLSYRRFFEVTGL
                     VGMRVEDKIVFDDTHRLILELVRTGAVDGLRIDHIDGLADPKAYLARLRQEVGPACYI
                     TVEKILAKGEQLPDDWPVSGTTGYEFIASLAEVLVDDKQIDNLRQAYETVTGAPVDMR
                     AELRAAKLLMVDRNFEGEFTRLLALALSIASELQIAQEESVVRQALRELLIAFPVYRT
                     YGTAEGLPPTDICLLHRIVERVKTLENPPQPEALTFLSRLLTGDVPVSSQEEATQFRV
                     RFQQLTGPLMAKSVEDTLFFRQNMGLALNEVGAEPVTHHFSIERFHHEMKTRQARQPD
                     ALSGTSTHDTKRGEDARARLYTLTEAPEQWSECLARWRQMNQTHVKFLNDGTAPKSAD
                     TWMLYQALTGVWPPMLQPQDETGLNALKIRFEAFVEKALREAKLRTDWVDSNEAYETA
                     MLDYARYLLAPDNQTFLQDFYRSLQPFIRAGLVNSLTQTVIKLTAPGVPDIYQGSEAL
                     NFSLVDPDNRREPDFATLAQQLDQLTPGVFSREESWLDGQVNQYATAALLRLRQQNHE
                     LFRFGDYIPLRAVGQRADKVIAYARVNHDDALIVVAPRLVFAECDGLLSQSHSGFWSG
                     TDIIIPGQLNQRRYRNVLTQERLMPGERLSLASHQGGVLVLMSD"
     gene            9035..11110
                     /gene="glgX"
                     /locus_tag="OPY25_003251"
                     /pseudo
     CDS             9035..11110
                     /gene="glgX"
                     /locus_tag="OPY25_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460517.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
     gene            complement(11223..12443)
                     /locus_tag="OPY25_003252"
     CDS             complement(11223..12443)
                     /locus_tag="OPY25_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCS0928796.1"
                     /translation="MDLISPCSHKAQKVCNNTGSVKWDFIERHFGDGAGKLLPMWVSD
                     FDFACPPEVQAALHQRIEHGVFGYSERDEAYFNALLHWFSSRHQLTLKQEWVCSVEGV
                     VPGLALLVQMLTHPGDGVVVQGPYYGSFAKIITLNGRKLLENPLSESPDEGYQMDFCQ
                     LERLFRHERPPLMILCNPHNPTGRCWSANELEQLLLLCEAYDVTLISDEIWADLLLPC
                     ETFTSVLHLGERWHKRVISATAASKTFGLSSLRISNFLIPDPTLRQRFLSRLDAHGLD
                     VFNALSVQAATTAWNESRQWLDSLLDYLAENRRWFVEQATEHLPWARIVPAQGTYLLW
                     MDCKKLGLDDEQLKWVMADVAGIAPSMGSGFGPAGSGFIRLNLGCPRTYLEMAIDGLK
                     RISVKTIKGIPTGG"
     gene            complement(12400..13102)
                     /locus_tag="OPY25_003253"
                     /pseudo
     CDS             complement(12400..13102)
                     /locus_tag="OPY25_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460515.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13168..14259
                     /locus_tag="OPY25_003254"
                     /pseudo
     CDS             13168..14259
                     /locus_tag="OPY25_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14452..14559)
                     /locus_tag="OPY25_003255"
                     /pseudo
     CDS             complement(14452..14559)
                     /locus_tag="OPY25_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1493 family protein"
     gene            complement(14560..14751)
                     /locus_tag="OPY25_003256"
                     /pseudo
     CDS             complement(14560..14751)
                     /locus_tag="OPY25_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002211098.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14905..15033
                     /locus_tag="OPY25_003257"
                     /pseudo
     CDS             14905..15033
                     /locus_tag="OPY25_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460510.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin, RelE/StbE family"
     gene            15027..15149
                     /locus_tag="OPY25_003258"
                     /pseudo
     CDS             15027..15149
                     /locus_tag="OPY25_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418669.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
     gene            complement(15201..>15853)
                     /locus_tag="OPY25_003259"
     CDS             complement(15201..>15853)
                     /locus_tag="OPY25_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /protein_id="HCS0928797.1"
                     /translation="ALICYLASHGERLDEYVDSSLFYKYPDAYRSVFSKKYGSLEIPS
                     AGIHFTWDLIQKIKDKGGLISFITLHVASTEMLSNRKIQTKCVEEVTINEEYYEVPQA
                     TADIINTAKQNGGRIFAVGTTVTRCLESAYSREHNCLKASSGWTALYIHPGYQLKVVD
                     CLLTNLHQPKTTHMVLTGQFAGVDLLMKAYASEDIQSCQFDMFGDCMLIIQDEGQG"
BASE COUNT         4148 a         3756 c         3841 g         4108 t
ORIGIN      
        1 gcgattttta tcatttatta caacgagata agataaatct taatatgaat gaaaatatac
       61 ataatggaat acgcttccgg aagaaaaagt aaggataaaa ggagggatat attctttaaa
      121 gaaagggagg cctgttggtt taatatccat cactgaaaaa gcatacaact attttctata
      181 tctgaagtgc gggtaatcga caacatgcta catccatcgg catgaacaac gcagattatc
      241 agcatagtct atactttatt ttttgagcca acaggagagc aaaaatgaca atccataaga
      301 aaggtcaggc acactgggaa ggcgacatca aacggggtaa aggtactgta tcaacagaaa
      361 gcggcgtgct taatcaacaa ccgtatggat tcaatacccg gttcgaaggc gcgcagggaa
      421 ccaacccgga agagttaatt ggcgccgcac atgcggcctg tttctccatg gcgctatcac
      481 tcatgctggg agaggctgga tttacgccga catccattga caccaccgct gacgtatcgc
      541 ttgataaggt ggaggcgggc ttcgccatta ccaaaattgc gctacaaagc aaagtggcgg
      601 tagcagatat tgatgcttca actttcgatc aaatcatcca gaaagcaaaa gccgggtgtc
      661 cggtatcgca ggttctgaat gcggaaatca ccctcgacta ccagcttaac gcctgataac
      721 ctcgtcagcc cggtaacgac tcttgtttat cgggctgttg aatatcgctt tttctccgtc
      781 tctcattttc tttacgctat cgggcgttaa aagtacacag atcgaatgaa aatgtatcag
      841 acgtcaggaa cctcgaaaag cgtcttctta ccgtgtcttt gttggtattc attacaggtg
      901 ttaatcattt tctttgcagc tccttttaat aaagaaagca ttaaatcatc ataatcaacg
      961 tagaatctgg ttgtttcggt ttccgttttt atctccccaa ttgctgctat ttcagtggct
     1021 aatttcaatt ttgccgcatc gatatcttta ttcgcttgtt tcactgtagc tgataagcta
     1081 gtaaagaaat tttgcactgt ttttagcctg ttattcaatt ctggaatcaa tttcccttca
     1141 atcacgcccg cagcaataga ataggaaata attaatccaa acggaccggc gactatgccg
     1201 gctgcagcac cggcataagc ttccttacga attctatcca cctgtgactg gaaataacta
     1261 cttttttccg aaaaatcatt agttaactgg ctatctaatg ccagcagttt tccggaagcg
     1321 ttgttgaaac tttgtgaact tgtcaggaga gatttttgcg cttcattcag tttcttgaca
     1381 ccatcatcta atatcctaat gagaatgtct ttctgggctg atgctttttt ctcattatat
     1441 tcatcaaata gtaaaatata cgctgagagt aattgcgtca cgacaccaca ccattcataa
     1501 acagtttgtg tcgcttcaaa atacttgtcc tggctgtcca taagcaaaac tttaatatca
     1561 ccaactaaaa cagaagcttc ctgcgagtac tcctgtttaa aacggcttaa ctcttttatg
     1621 gtttcatcaa aggtcttcca ggggatgacc tggtcgaggt atttgttata aagatctaat
     1681 gccccatctg cggtttcgat cgcgctttta actacctcta cagtttgttc tgcaaatatt
     1741 ccggtcataa tcatttgcct ctttaaatat ataaattgca attaagtacc tgttttataa
     1801 agtattctta cctattacct ccagacaact tttgtagctt taacattcca gaagctggaa
     1861 atactgcctg cttcctgctt atctacgcag ggtacgatta ctctgctgca ttttctccag
     1921 aatacgacca aaagaaactg ttttgcttcc tactttcacc attccatctt ccggcaagta
     1981 gctaaatttg acgtacagta tatttttgct gattttatct ttttgcttca tagccaaaat
     2041 ggcttgctgt aatgctttta ggtcggaggg gattcccacc gcatcggtga tatcggtacc
     2101 gggcacaaat ttcgatacct gatcaacagt ttgagtcaat atatcctgta gcggaaataa
     2161 gccggtaaaa cgttgtttgg gtttatattt tgtcactccc atataaatgt caggtagacc
     2221 tttaatgtgg ttttcaatgc tgcgagtttt attttgcaac ataaattcgc taatctctac
     2281 cggagagccg atcaatacca gcggcttcac tcctgcacct ttttcggaaa agagatagtt
     2341 attgctgctg ctttttactg ctttttgcaa ctcgccacga tccatgatta agctgtaata
     2401 tttaccctct ttcacaacag gtttgggttc acgccacata ttgatatcgc tagcttgtgc
     2461 catactggat accatcatgt aaccgaaaaa cgccaatgtt acggatagtt tcattaactt
     2521 taccttttta attagccaaa aaaaatagca ctcgtaaaaa gtataaagcc gtggttgcaa
     2581 caaaacttaa acgtcgctca cttaaccgat aagcatttat ttatcttaat tatataaatt
     2641 tccctccaaa taatacctga attattaccc tttggattca actgcttgca gttatagtgc
     2701 taaataacaa taaatctact ggaagtatac agtttgtgtg caaaaggtat ttttatgatt
     2761 acggaaacct gaaattgtcc gactatctgt aaatgctatg aaattgtatt gtagattcga
     2821 ttgcgcccgg tgctgatgac taccggggca atagtggttg gtttagccct gataaggttc
     2881 gccagcggtg tagacaccgc aagccgtttt ggacagggct ggtggttgcc tccgggatgc
     2941 tgacaggcaa tctgtttacg atgtttgttc tgcccaccgt ttgtgtctgg ctggcgcgcg
     3001 attgcgacgg catgtcagag cgaagttctc tttcatcagc tcaacgtagc gcatactcgt
     3061 catttgctgt tgtcgtggtc tactttttcg ccctaaaatc tgctcgccat gttgctttat
     3121 tcatcaaaca tcaaaatcag tcaacgtaaa tatcaataat agccatatca cggagggtga
     3181 tctttattcc tgagagaggt ggggtattat tttctgcgtt ctacattaac gggttaacgc
     3241 gcagatgtag aggttattta tataattatt ggagcaacaa caatgaataa attctccctt
     3301 gctacagcag gtattatcgt ggcagcgctg gtaaccagtg ttagcgtgaa tgcggcaaca
     3361 gatactacta aaacaaacgt tacgcctaaa ggtatgagct gccaggagtt tgttgacctc
     3421 aatccgcaga cgatggcgcc agtcgctttc tgggtgctga atgaagatga agattttaaa
     3481 ggcggggact acgttgattt ccaggaaact gagacgacag cagtgccgct agccgttgag
     3541 ctttgtaaga aaaacccgca gagtgaatta agcaaaataa aagacgaaat caagaaagaa
     3601 ctctcaaaat aagagtaaac tgatatcaaa acccggcctg tgtgtcgggt tttactattt
     3661 gtgacaccgt cacaaatagc atcttccatt tcttctacca atcacgtggt attgcactat
     3721 tttcattaga gccctttcac tatatggaga cctaatgaaa attttaccgc tggcactctt
     3781 tatcattcct tttctggccg gatgcggcgc caataatacg ccgccgcaaa cgcctattcc
     3841 cggggaaaaa acatctgcca aattacgtac cctggaaaca ggcgcggcgg ctattcaatc
     3901 cagaccacct gtcgatgcca tcagtaccta ccttgacggg ttccattttt atagcggtga
     3961 taaaaacgga cagatggaag cgcaccatta cgttaccgtc ctgaacgaag atgtcatgca
     4021 ggcggtgatt tacgacggca atacgaaaaa cgcgcgcctg atgggggtgg agtacattat
     4081 cagcgaacgt ttatttaaaa cgcttcctcc cgaggaaaaa aaactgtggc acagccacca
     4141 gtacgaggtg aaatccggta gcctggtggc gccaggctta ccgcaggtcg ctgataaggc
     4201 gttgatgagt aagattgtta atacttatgg caagacctgg cacacctggc ataccgaccg
     4261 ggataaaacc ctgccaatgg gtatccctgc gctgatgatg ggctttaccg gcgacgggca
     4321 gcttgacccc gcgctgctgg ccgatcggga tcgccgtctg gggattgata cccaggccat
     4381 taaacgcgag cggcaggatc tgcctgaaca tcccgttatc aagggggcta acgcctggga
     4441 gcagggagaa gttatccagc tacagcgtgt tcagggctct ggcgaacacg ggcgaggcga
     4501 taccgcgcac ttcggtatat ctgagcaatc ccgacaataa ttccacggtt ttacacgcag
     4561 ataggaaaaa gaatgcctgt taagtgacag tgtcacgtaa aaattagccc catagtctat
     4621 gcttgttttt cggatgctgt agaggttatg agttaaacgg agcgacaaat gagttcaaaa
     4681 attttttgca aaagctgggg ggctgaatat atcgccgctg atgtcgtccg ctttcgtctt
     4741 tgggccaccg gtcagcaaaa ggttatgctc aggcttgcgg gtaaagacca ggaaatgcag
     4801 gcgagcggtg acggctggtt tacgctggat gtatccgggg tgacgccagg tacggagtat
     4861 aactttgtac tcagcgatgg catggtgctc cccgatccgg cttcccgcgc ccaaaaaact
     4921 gacgtcaatg gtccgtcata tgtgattgat ccaggcagct acgcgtggcg caacaccggg
     4981 tggaaaggca gccgttggga gcaggccgtg gtgtacgaga tgcatacagg cacgttcact
     5041 ccggaaggca ccttccacac cgcaatagcg aagctgcctt atctcgctga actcggcgtt
     5101 accgttattg aagtgatgcc cgttgcgcaa tttggcggcg agcgcggctg gggctatgac
     5161 ggcgtactgc tttacgcgcc gcattctgcc tatgggacgc cggatgattt caaagcgttt
     5221 attgacaccg cgcatgggta tggtctttcc gtcatcctgg atattgtgct gaaccatttc
     5281 ggcccggagg gaaattattt accgctattg gcgccggcgt ttttccacaa agagcgcatg
     5341 acgccgtggg gaaatggtat cgcctatgat gtcgacgccg tgcggcgcta tatcatcgag
     5401 gcgccgttat actggctgac agaataccat ctcgacggct tacgctttga cgctatcgat
     5461 cagattgagg acagtagcgc caggcatgtg ctggttgaaa tcgcacaacg tattcgggaa
     5521 gacattaccg acagacccat tcatctgact accgaagata gccgcaatat tatttctctg
     5581 catccccgtg atcaggatgg caatgcgccg ctgtttaccg ccgaatggaa tgacgatttt
     5641 cataatgccg tccacgtttt tgcgaccgga gagacccagg cctactacaa cgattttgct
     5701 gatgccccgg aaaaacacct cgcaagagcg ctggccgaag gattcgctta tcagggggaa
     5761 atctcaccgc aaaccggcga acctcgcggc gtaaaaagta ccggacaacc cccggtcgcc
     5821 tttgtggatt ttattcagaa ccacgatcag gtcggtaacc gcgcccaggg cgacagactg
     5881 ataaccctgg cgggtgctga acgaacaaaa gtattgctcg ccacgttgct gctttcaccg
     5941 catattcctc tgctttttat gggcgaagag tatggcgaaa gccgtccttt tctttttttt
     6001 accgatttcc atggggattt agcccgcgcc gttcgtgaag gtcgcgcaaa agagtttgcc
     6061 gatcatgcag gggaaaatgt tccggacccg aatgcgccag agacctttca acgctcaaaa
     6121 cttaactgga agcaacagca cagtgaagag ggtaaagcgt ggctggcatt tacccgcgaa
     6181 ctactgcttt tgcgccagaa gcatatcgtg ccgctgttgt ccgctgcccg tgagagctca
     6241 ggaacggtat tgcaaaccgc gcccgggttt attgccgtta gctggcgttt tccgggagga
     6301 acactgtcac tggcgctgaa tattagcgcc acgacggtat tgctgcccga tttaccgggt
     6361 aagactctct tcgcctggcc gaatgaatcc accgggtcgc tttcccaaca ttctcttatt
     6421 gtccgcttag cccagggaga gtctgcatca tgatcccaac tgcaacgtat cgtcttcagt
     6481 ttcgcaatag catgaccttc gatcgcgctg cggcgctggt gccttacctt aaaaatctgg
     6541 gtatcagcca tctttatgcc tcacccatct ttaccgccac caaagcgtca acgcatggtt
     6601 atgatgtcac cgatgcgaat gagattgagc cttctattgg cgggcgcgaa ggatttgaaa
     6661 gactggtggc tgaacttaaa gcacaaggtc tgggattgat catcgatatt gtgcctaatc
     6721 acatggccag ctcgctggaa aacgcctggt ggcgcgacgt gcttgaatat ggcaaggaga
     6781 gccgttacgc gcgccatttc gatattgact ggtcgcgccg actgacgctg ccttttttag
     6841 gcgacacgtt tgacgccgtg ctgggaaacg gagaaattgc gatcaagccg gatcccgtta
     6901 cgggtaaacc cacgttcgcc tattatgata attattatcc gcttgcgcca gcgacgtggc
     6961 aggggcgcga ggctgaaata ctggcgctta ccgataaagc cgctattgct gatttgcatg
     7021 agcgccagcc gtggaaatta atgtcttggc gcgatgccgc tcgctcgctt tcatatcggc
     7081 gtttctttga ggtcacaggg ctggtgggaa tgcgggtgga agataaaatc gtcttcgacg
     7141 atacacatcg gctgattctg gagctggtca gaacgggggc ggttgacggt ttacgtatcg
     7201 atcatatcga cggccttgcc gatccgaaag cctatcttgc gcgtttacgt caggaagtgg
     7261 gaccggcgtg ctatatcacc gtggaaaaaa ttctcgctaa aggcgagcaa cttcctgatg
     7321 actggccggt ttccggcacc acaggctatg aattcatcgc ctcgctggcg gaagtactgg
     7381 ttgacgataa gcagatagac aatctgcgcc aggcttacga gaccgtaaca ggcgcgccag
     7441 tggatatgcg ggcggaatta cgggcggcta aattgctgat ggtcgatcgc aattttgagg
     7501 gggaatttac ccggctgctc gcgcttgcgc tgtcgattgc cagcgagcta cagatcgcac
     7561 aggaagagag cgtcgttcgg caggcgttac gcgagttatt aattgccttt cccgtatatc
     7621 gcacttacgg cacggcagaa gggctaccgc cgaccgatat ttgcctgtta caccgtattg
     7681 tggaacgggt aaagacgctt gaaaaccctc cgcagccaga agcgcttaca tttctgagcc
     7741 gtcttcttac cggcgatgtt cccgtctcca gccaggagga ggcgacacag tttcgcgttc
     7801 ggttccagca actcaccggt ccgctgatgg cgaaatcggt agaggatacg cttttctttc
     7861 gtcaaaacat gggactggcg ttaaatgaag tcggcgccga gcccgtcacg catcacttct
     7921 ccatcgaacg ctttcaccat gagatgaaaa cccgacaggc gcgacagcct gatgcgttat
     7981 ccggtacgtc gacccacgat accaagcgag gcgaggatgc gcgagcacgc ctgtatacgc
     8041 ttaccgaagc gccggaacag tggagcgaat gccttgcccg ctggcggcag atgaaccaga
     8101 cccatgtcaa atttttgaat gatggcactg cgccaaaatc ggcggatacg tggatgctat
     8161 atcaggcgct gaccggcgtc tggcccccga tgctacaacc acaggacgaa acaggtttaa
     8221 acgcgctgaa aatacgcttt gaagcctttg tggagaaagc gctacgcgaa gcgaagctac
     8281 gtaccgattg ggtggacagt aatgaggctt acgaaacggc aatgcttgat tacgcccgtt
     8341 atttactggc gccggataat cagacatttt tgcaggattt ttatcgttcc ttgcaaccct
     8401 tcatccgcgc aggactggtt aacagcctga cgcagaccgt tatcaaatta accgcgccgg
     8461 gagtacctga tatctatcag gggagcgagg cgttgaattt tagccttgtc gatcccgaca
     8521 accgccgcga accagatttc gccacgctgg cgcagcagtt agaccaactg acgccgggag
     8581 ttttctcgcg cgaagagagt tggctggacg ggcaggtgaa tcagtatgcc accgccgcct
     8641 tactgcgttt gcgtcagcag aatcatgagc tcttccgttt tggcgactat ataccgctgc
     8701 gggctgttgg tcagcgtgcc gacaaggtca tcgcttacgc cagagtcaat catgatgatg
     8761 cgctgattgt tgttgcgccc cgactggtgt tcgccgaatg tgacggctta ttatcacaat
     8821 cgcatagcgg tttctggtca ggaaccgaca ttattatacc cggacagctt aatcagcgtc
     8881 gttatcgcaa tgtgcttacc caggagaggt taatgcctgg tgaacgcctg tcgttggcct
     8941 cacatcaggg cggcgtactg gttttaatga gcgactgagt ttatgtgttg atgtgccgtg
     9001 acaggacaac gtttaccgtg ggtggagaaa gagaatgaca acaaacaggg cttttgaaat
     9061 cagatcagga tacagccata cgcttggcgc gaattatgac ggcgaaggcg tgaatttcgc
     9121 tattttttcc gcccatgcgg aacgcgtcga gctttgtctt tacgatccga gtggggagca
     9181 tgaaatcgct cgtctggagt taccggaata taccgacgaa atatggcacg gctatgtcac
     9241 gaagttgcag cccggcgcgc tgtatgggta ccgcgtttac ggtccttatg acccggaaaa
     9301 tggtcatcgt tttaacccca ataagctgct tattgaccct tatgcccgtg agctggtggg
     9361 cgatattcag tggaacgatg cgcatttcgc gtatcaatta cttcatgacg ataaagattt
     9421 gacctttgat gaccaggata gcgcgccatt tacgcctaaa tgtcgggtga ttgatccggc
     9481 tgaggctaac tgggaggata gacaacggcc ttccataccg tggtcgaacg ccattattta
     9541 tgaaacgcat gtaaaaggct ttacccagct taattcggcg atccctgagc ctctacgcgg
     9601 tacgtttgag ggcatggggc ataaagccag cgtggattac attaaaagtc tggggattac
     9661 ctccgtcgag cttttacccg ttcactggtt cccggacgat cagcatctgc tcgataaagg
     9721 actgaaaaat ttctggggat ataactcgct gggctttttt gcgccggcga cgcgctacta
     9781 tggtccaaaa ggtattcagg gattccgcga tatggtgcgc gctttccatg atgccggcgt
     9841 cgaagtgata ctggatgtgg tctataacca tacggcagaa gggaatgaac ttggccccac
     9901 gctgtcattt aaaggtatcg ataacttctc ttactatcgc accatgcccg atcagcatcg
     9961 ctattatatt aacgatacag ggacaggtaa taccgtcaat acctctcatc cacgggtact
    10021 gcaaatggtg atggattcgc ttcgctattg ggcggagtca atgcatgtcg acggctttcg
    10081 ttttgatttg ggcaccattc ttggtcgtga gccggaaggc tttgatcaga gaggcggctt
    10141 ttttgatgcg gtaacgcaag acccggtgct ggcaaaactg aaactgattg gcgaaccctg
    10201 ggatatcgga ccgggcggct atcaggttgg cggttttcca ccagggtggg gcgaatggaa
    10261 tgataaatat cgcgatacgg ttcgcgaata ctggaaaggt gacaacgtca caaatgattt
    10321 cgccgcacgc ctgctgggtt ccggcgatct ctacgatttg cgcggccgtc gctcctggtc
    10381 aagcgttaac tttattactg cccatgacgg cttcacgctg aacgatctgg tgtcttataa
    10441 cgacaaacat aatgaagcca atggcgaaga taataatgac gggcataatg ataaccgctc
    10501 ctgtaactat ggcgcagaag ggccaaccga cgacgagggc atcaatgcga tacgcgagcg
    10561 acagaaacgt aatttcctga ccaccttact tttctcacac ggcacgccga tgttattagc
    10621 gggcgatgag tttggccgca gtcagatggg caataacaat ggctactgtc aggacagtga
    10681 aatatcgtgg gtccactggg ataatttgcc ggaaaccgcc aatgcgctac gggagtttac
    10741 ccgtcatctg attcaactgc gcgccacgca accgttgctg cgccgggaga gctggcgtga
    10801 cggtctggag atccgctggt ttaacgccgg cggaggggcg cagtaatccg aacaatggga
    10861 tgagggatcg acgataggcg tatgtattag tcgacccgat cttcagccgg aagcggggat
    10921 ctggcatgac gccttactgc ttttcaatcc gtttgaaggc agcgtaccgt tccgtattcc
    10981 gatgtgggga gaaggcggct gggtgcttga actgacgact gccgatgacg cgcagcaggg
    11041 aatgcggatt accgaagaaa tggatttcga tctggccggg cgcagcatcg tgttattcag
    11101 acgcccctga tagtgaaact gcgctccgga cccaaccggc cttaatggcc ggttttttac
    11161 tggcgctcag gcgatatcat gccgcagaaa taacaccgtt gtcagtttac cgcccgaaaa
    11221 attcatccgc ctgttggtat tcctttgatt gtcttcaccg atattcgctt caggccgtct
    11281 attgccattt caaggtaggt acgtggacat cccagattta aacggataaa tccgctgccc
    11341 gccgggccaa agccgctgcc cattgaagga gcaatacccg cgacatccgc cattacccat
    11401 tttagctgtt cgtcatccag tcccagtttt ttacaatcca tccataataa ataggttccc
    11461 tgcgccggga caattcttgc ccagggaagg tgctctgtcg cctgttcaac aaaccagcgg
    11521 cggttttccg ccagataatc cagtagcgaa tccagccact gtctgctttc attccatgcg
    11581 gtagttgccg cctgaacgga gagggcgtta aagacatcca gcccatgagc gtccagacga
    11641 gacaggaaac gctggcgaag cgtaggatcg ggaatgagaa aattagaaat tcgcaacgac
    11701 gataagccaa acgttttgct ggccgcagtg gcggagatga cccgtttatg ccagcgctcc
    11761 cctaaatgca gtaccgaggt aaaggtttcg cagggcagca atagatcggc ccatatttca
    11821 tccgagatga gagtgacatc ataagcttca cataataaaa gcagttgctc cagctcgttg
    11881 gccgaccagc aacgcccggt tggattatgt ggattacaca aaatcattag cggagggcgc
    11941 tcatggcgaa acagcctttc cagttggcaa aaatccatct ggtagccttc atccggcgac
    12001 tcgctaaggg gattctccag cagttttcta ccattaagcg tgattatttt ggcgaaggag
    12061 ccatagtatg gcccctgaac cactacgccg tcgcctggat gcgtcaacat ttgcactaag
    12121 agcgccaacc ctggtacgac gccttccacg ctgcataccc attcctgttt taacgtgagc
    12181 tggtggcgtg acgaaaacca gtgaagcagg gcgttaaaat aggcctcatc acgttcgcta
    12241 tagccaaata cgccgtgctc gattcgctga tgcaatgccg cctgaacctc tggcgggcag
    12301 gcaaaatcga aatcagaaac ccacatcggc agcagttttc cagcgccgtc gccaaagtga
    12361 cgctcaataa aatcccactt taccgaacca gtattgttgc acaccttctg cgccttgtgg
    12421 gaacatggcg atatcaaatc catcaatgaa agcgtccagt ccctgtttga tgctcagtcc
    12481 ctgcatgatg acgccgagga acaaggcaag tacgcaggcg cttaacatta atgggatgac
    12541 aggctttttg cgaattgcgc cccacagtac gatcaccggc ggcaaaataa gaacaatatt
    12601 aaaatggtat agcgactcca gcgagtggat gatgtccgta acgcgctgcg gcgtagccac
    12661 ctcgcccagc atattactgt gtccggcgat aagataaacc acggcggcaa gcaggaaact
    12721 tggcagggtc gtccaaagta aatgctgaat atgctcaaac agagtagtgt ctgcgacaat
    12781 cgcggcaaag ttagtcgagt cggacaacgg tgagattttg tcgccgaaat aagcgccaga
    12841 aacaacggcg ccagctgctg ctgcaagcga cacgtccagc ccggcggcaa cccccattaa
    12901 cgcaacgcca accgtcccgg cggaccccca cgatgtaccg gtacagacgg agaccacgct
    12961 ggttaaaaag aaggctgcaa tcaaaataga tacgtagccc catgatgccg taaccgataa
    13021 tcaacaataa caacatggag atgactggga ttagcgctaa acccaatgac agcgttttct
    13081 tcttgttttg tgatgcactc ataatggagc tccggtcagt aaggtagtag tattacaaaa
    13141 agcatacaga atgaatatgt tttattgatg gaaaacgctt tttctgaaaa atataaatat
    13201 gcatttagaa atttagaact gaaagaatta cgtagattca ttctgaaaga gctaattagc
    13261 tctcccgagt tagataatca acttacaaac ctaatcgtgt tgctaaataa attttgggat
    13321 actcacgccg cggcgcttat aacagaagtg cgggcgtcta aaagttatcg attattactt
    13381 ccgattcaac ggtttggtta taacatatct aatcatctta gatctctggg gatttatttt
    13441 gatagcatca taatggttga tccattacat tttccttctc ttagctctct gcattcattt
    13501 ttgtcattgc caccagataa tagttatgtc cgcatgcgca gattggtatt acttgaacat
    13561 gtttccaatc tatttcgcgc catcccattt atgactattg atgatgatta tccaattttt
    13621 ctaatcgttc ctgaattact ggattttgat aaagaacgca atcatgaaca atctgccgct
    13681 tttctaagtc agctcttttt taaagataga aaaatggatt acgctactta tttagcgttt
    13741 cttgagcact ttgggagaaa tgaagaaaca ttccagaaga tcctaataaa taaagaatta
    13801 ttaaaaacat tgcttgataa tttcaataac atcgaaaaag aggtctgggt ttacgataca
    13861 gatttaaaga gttttacaac aagagaggta gatcttctgg attacgatct gccgtcagct
    13921 ataggaacct tactgggtaa ggttgaaggt gcaatttatg cacagcgatc aactcaatta
    13981 tcggcaacac tattaggtat tgatccggtt atttatagta accatatgtt tttacatgaa
    14041 tggactacgg agcagttggt caaggattat ggtaaattaa atcctctttc ttctgaagag
    14101 caagcgatta caatgggact atcagccgcg gaagtaaaat tccttactgc gctttccgat
    14161 ctggaattaa aaaagattag agaaagaggt caactggaat ccttaaggca tgaactaaga
    14221 atctcaaggc atgacttgca aggaaaacgt gtgcaggata agcgggtgca aatcaacaga
    14281 attcgcgcag cgtcacggca gggaagggat caaacttatg ggccagaagt tttttgacat
    14341 gcacgaatcc agccgcctta acatgtcttt taattgttct ggtgcattta acataatata
    14401 cattatgcgc tccatgatga tggagaacgg aaagcagccc ccaagcgtga atcagtcata
    14461 caaccagcga ccagccctgg cagacgcaat gagcatacct atcgtgaact ccggcgcctg
    14521 aggaatatcg tttttgcgaa acggattaag caaatgctta gcaccacgcg gttttgtccg
    14581 cgtaggcaaa acattcaatc cagccacaat agacactatc gccccaaaat cctgaacacc
    14641 caactgattg gcagtgtttt cgcagaaaat cataaacagc aactgactag cagtcagatt
    14701 tgaacgtccg gcataaaaat aagtgctatt aagctcttca actgtatcca tactctaatt
    14761 tcctgattaa attaacttta tgcattggca atgcaaccac tttataggat tgttataaca
    14821 catttgttcg tcgtgtgctt gaattagaca atggcaagct ggtgcgcacg ctgttaacgt
    14881 tcctggtaat cgatacaagc agttaagtac aaaattaagc cgtgtggtgc aggatacaga
    14941 ctggtctaca gcgtcgaaga tgaaattatc acggtaactg tcattggtgt tggaaagcgt
    15001 gaaaatgatg ccgtctacaa cttaacgacg tgatggcggt gaaacaggag atatttgcct
    15061 atccccctta tcctaactgg accgctgttg gcgttacctg gctggccggc tttgatttcg
    15121 aaataaaggt tattgcccga atcccctgat gcttattctc ggtaaaaccg gtagcattat
    15181 gtgtaccggt tttattttat tcatccctgc ccttcatcct gtatgattaa catgcaatca
    15241 ccaaacatat cgaactgaca tgactggata tcttctgagg cataggcctt catgagtaga
    15301 tcaaccccag caaactgacc agttaacacc atatgcgtcg tttttggctg atgtaagttc
    15361 gttagcaggc agtcaaccac tttcagttga tagcctggat gtatataaag cgcagtccag
    15421 ccagaacttg ctttgaggca attgtgttcc ctcgaatacg cggactccag gcatcgtgta
    15481 acggtagttc ctacggcaaa aatacgtccg ccattttgct tcgcagtatt aatgatatcc
    15541 gctgtagctt gtggaacctc gtagtattct tcgttgatag tcacttcctc tacacatttt
    15601 gtttgtattt ttctgttgga caacatttct gttgatgcaa catgtaaagt aataaaagat
    15661 attaacccac ctttatcttt gattttttgg ataagatccc aggtaaaatg aatgccggca
    15721 gaaggtattt ccaaagagcc atacttttta gaaaaaacgg aacggtaagc atctggatat
    15781 ttataaaaca agctggagtc cacatactca tcaagacgct caccatgact ggctaaatag
    15841 caaattaaag cct
//
LOCUS       DAJVKX010000102        15845 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000102 DAJVKX010000000
VERSION     DAJVKX010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15845
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.102"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..831
                     /gene="tagK"
                     /locus_tag="OPY25_003260"
     CDS             <1..831
                     /gene="tagK"
                     /locus_tag="OPY25_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     TagK"
                     /protein_id="HCS0928798.1"
                     /translation="GTYIVFTAAAPYIPLFEQHGKDDIALSLVRHEEAWWIVNHSDEL
                     CCAVNEQVMEPHHRMRLNDGDTIEWGLSSWCLARTNDESRPDVSFPQLVQSSESVAEY
                     LDLDWFKQQQLNPQNPFDIIPVRETAPSYTGHEADSTLHQLYQEYQQALRPSGQEKPL
                     RPKPFPRNEDAVTQDLTSLYDKKGDTDTLQDMVAGAPGIDAILDTLDTTGEGEMHWLA
                     MESMPDILQLLSPEMGGKTAHSEILPDLTRREHRIIGIDSHYRITPTQKNGNTAHEKN
                     "
     gene            818..1642
                     /locus_tag="OPY25_003261"
     CDS             818..1642
                     /locus_tag="OPY25_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="impE family protein"
                     /protein_id="HCS0928799.1"
                     /translation="MKKTDTLPATLSALLQEYSIAEGIQMAEQQVRENPAKALCRHSL
                     FQLLCVAGDWARALHQLQLCARMEANYTQEARLYRELVCCEMFRHTVFQGEQRPGFLL
                     PQPVWVESLLAALACHDDTGEVDKHRNTALEAITDTGGQWNGGAFDWASDSDSRLGPV
                     LELVTGGVYIWLPFSQIRSLESPQPTRLTDLLWKPVNITLVNGDTHGAWLFTRYSGSE
                     SASDALRLCRETAWQDGPGETTVRALGQKVWLTSHGDISLLDMTHCTFHAQENDGA"
     gene            1639..2133
                     /gene="tssE"
                     /locus_tag="OPY25_003262"
     CDS             1639..2133
                     /gene="tssE"
                     /locus_tag="OPY25_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HCS0928800.1"
                     /translation="MSTSRFTPANHLLPTLFDRLCDNAPYQKIDRDISVTPVQLKEII
                     RRDLSFLLNTISHEGDIDARRYPQAAASVLNYGLPPLAGSFMYEHKWDDISEAIRRAI
                     IRFEPRLNAATLRVTPLLDEARQGSYNTLQFEIRGQILTQPYPTEFLVRSALDMELSR
                     ITFF"
     gene            2149..4032
                     /gene="tssF"
                     /locus_tag="OPY25_003263"
     CDS             2149..4032
                     /gene="tssF"
                     /locus_tag="OPY25_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HCS0928801.1"
                     /translation="MDPRLLEYYNRELSYLRETGAEFATLHPKIAARLGMQGTDIADP
                     YVERMIEAFSFLSARTQLKIDAEFPRFTQRLLEVVNPNYVTPTPSMAVVKLYPDTQEG
                     DLAKGVTVPRDTAFVSPIPEGENTACQFRSSQDVTLWPLSIEEVRLTAAPPDMPALHR
                     YLPPNIHVAGALRITLRTFGELAFSELAGPARLPFYLCGEERIASHLFELLHTSAVAT
                     LAGEPGHFDGELNVNLQHPVAHEGLEPGQGLLPLAWNVFHGHNLLHEFFACPERFYFF
                     TPTGLSAGLQKVQGNVAEIVILLNRLPPDWLIHQTDAAQFSLFCTPVINLFPRTTTRI
                     EVTHSVTEQHLVVDRTRPLDYEVFSVQEVEGLEAETTRKMIFRPLYHTRNNDEGNHGR
                     YFSLRREPRRSSESARRYGTRTPYTGSEVFLSLVDQHEAPYPENLRHITVTAMVTNRD
                     LPCLIPRNGRDDLTVDAAIPVAGVGLIRPPRPPQPPLAEREMAWRLIRQLSFNYLPLA
                     DLDHRTGGQALRDLLNLFIPAHDSPQSRQVRSLIGCKTTPVTRRLPGSGLLVYGRGVS
                     CELTVDEEGFSGISPYLFGLVLEHYIARHVSINTFSQMTLHSMQRGHVMTWPVRTGQR
                     GSV"
     gene            4029..5024
                     /gene="tssG"
                     /locus_tag="OPY25_003264"
     CDS             4029..5024
                     /gene="tssG"
                     /locus_tag="OPY25_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HCS0928802.1"
                     /translation="MTGALDQAQKAPWRYGFLNLMRRVDAQLCDTPAGSIWQPRMEKF
                     RLGQTPTMTFAPREIAQVSWQDGRLHLSLYSLGLWGPNGPLPLHYTELALNRSESRHD
                     PTLVHFSNIFHYRWLTQFWQAWRSGQSAGGGLDKPEHDRFAFYIASISGQDLRESAES
                     PLSDHVRLAASAHLVRESRNPDGLAATLAHYFSVPFAVKEFALHWITVANDEITRLGT
                     PAQSSVLGNGALIGQAVPDMQYKFRLIIGPLTLEDYLRFLPGGNNLPVLTELVRTFIG
                     FEYCWEIELQLKPHAAPPAVIGGAQRLGWTAWAGKAMHDRPVTGMIFEPEHGLTH"
     gene            5035..6089
                     /locus_tag="OPY25_003265"
                     /pseudo
     CDS             5035..6089
                     /locus_tag="OPY25_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459263.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImpA family type VI secretion system protein"
     gene            complement(6409..6485)
                     /locus_tag="OPY25_003266"
     tRNA            complement(6409..6485)
                     /locus_tag="OPY25_003266"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6449..6451),aa:Asp,seq:gtc)
     gene            complement(6619..7350)
                     /gene="dnaQ"
                     /locus_tag="OPY25_003267"
     CDS             complement(6619..7350)
                     /gene="dnaQ"
                     /locus_tag="OPY25_003267"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HCS0928803.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVINRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPVFADVVDEFLDYIRGAELVIHNASF
                     DIGFMDYEFGLLKRDIPKTNTFCKVTDSLALARKMFPGKRNSLDALCSRYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMTFAMEGETQRQQGEATIQRIVRQASRLRVVFAS
                     EEELAAHESRLDLVQKKGGSCLWRA"
     gene            7414..7881
                     /gene="rnhA"
                     /locus_tag="OPY25_003268"
     CDS             7414..7881
                     /gene="rnhA"
                     /locus_tag="OPY25_003268"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HCS0928804.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYTLTTN
                     NRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVD
                     LWKRLDAALGQHQIKWVWVKGHAGHPENERCDELARAAAMNPTQEDSGYQAEA"
     gene            complement(7878..8600)
                     /locus_tag="OPY25_003269"
     CDS             complement(7878..8600)
                     /locus_tag="OPY25_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCS0928805.1"
                     /translation="MKPARLSQTVVAPGCWGELPWGNYYREALEQQLNPWFAKMYGFH
                     LLKIGNLSAEINSEACAVSHQVNVSSQGSPMQVLADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPLSLMGLRKLVLVLRKTPPYNSRMFTLMRQL
                     DWLSLLNFEVLHYSRFHVLPWKKQGGRLLNTHIPALGCLQLIVARKRTIPLTLNPLRH
                     NKSKTPIRQTVGATRQYRKPDG"
     gene            8635..9390
                     /gene="gloB"
                     /locus_tag="OPY25_003270"
     CDS             8635..9390
                     /gene="gloB"
                     /locus_tag="OPY25_003270"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HCS0928806.1"
                     /translation="MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAAHKW
                     MPEAIFLTHHHYDHVGGVKELLQHFPQMTVYGPAETQDKGATHLVGDGDTIRVLGEKF
                     TLFATPGHTLGHVCYFSHPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTL
                     ICSAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLR
                     TEDIDLINEINKETILQQPEARFAWLRSKKDTF"
     gene            9462..10829
                     /gene="mltD"
                     /locus_tag="OPY25_003271"
     CDS             9462..10829
                     /gene="mltD"
                     /locus_tag="OPY25_003271"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HCS0928807.1"
                     /translation="MKAKAILLASVLLVGCQTSQNTGNVQQHAQSLSAAGQGEAGKFT
                     SQARWMDDGTSIAPDQDLWAFIGDELKMGIPENSRIREQKQKYLRNKSYLHDVTLRAE
                     PYMYWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQT
                     RNYDARRDVVASTTAALDMMQRLNKMFDGDWLLTVAAYNSGEGRVMRAIKANKARGKP
                     TDFWSLSLPRETKLYVPKMLALSEILKNSKRYGVRLPTTDESRALARVRLNSPVEMAQ
                     VADMAGMSISKLKTFNAGVKGSTLGVSGPQYVMVPKKHAEQLRESLASGEIDAVQSQL
                     IADNTPLNSRSYKVRSGDTLSGIASRLGVSTKDLQQWNNLRGSRLKIGQSLTVGAGSS
                     AQRLANNSDSITYRVRKGDSLSSIARRHGVNIKDVMRWNHDTDNLQPGDQLTLFVKDN
                     STPDS"
     gene            complement(10885..11655)
                     /locus_tag="OPY25_003272"
     CDS             complement(10885..11655)
                     /locus_tag="OPY25_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCS0928808.1"
                     /translation="MTTHSHHDNVEKQFGSQANAYLHSAVHAAGRDLARLAQRLSDFS
                     HASVLDMGCGAGHASFVAAQHVNSVVAYDLSASMLEVVAGAAEERHLSNITLRQGYAE
                     KLPFEDASFEVVISRYSAHHWHDVGQALREVYRVLKPGGVLIIMDVMSPGHPVRDIWL
                     QTVEALRDTSHVRNYSSGEWLAMVNNAMLVTNTVITDRLSLEFRSWVTRMRTPAPLVE
                     AIRLYQASAPVEVKRYFELQDDGSFSSDTIMLEAHKAV"
     gene            complement(11733..12533)
                     /locus_tag="OPY25_003273"
     CDS             complement(11733..12533)
                     /locus_tag="OPY25_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCS0928809.1"
                     /translation="MRKNTYAMRYVAGQPAERILPLGSFASIGQALPAGEPLSSEERI
                     RILVWNIFKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNVHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRPRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVNEASVLVTRASDHNPLLVEFSPGKPEQ"
     gene            complement(12665..13840)
                     /locus_tag="OPY25_003274"
     CDS             complement(12665..13840)
                     /locus_tag="OPY25_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928810.1"
                     /translation="MPLALFALTISAFAIGTTEFVIVGLVPTIAQQLAVSLPSAGMLV
                     LIYALGVAIGAPVLTALTGRLPRKQLLVALMVLFTAGNLLAWQAPGYMTLIAARLLTG
                     LAHGVFFSIGSTIATSLVPKEKAASAIAIMFGGLTVALVTGVPLGTFIGQHFGWRETF
                     LAVSLLGVIALMSSQLLIPANIPGRAAASIRDQVKVLTHPRLLLIYAVTALGYGGVFT
                     AFTFLAPMMQDLAGFSPAAVSWILLGYGVSVAIGNIWGGKLADKHGAVPALKFIFAAL
                     FVLLMVFQVTASTQYAALATILVMGIFAFGNVPGLQVYVVQKAEQFTPNAVDVASGLN
                     IAAFNIGIALGSVIGGQTVAHYGLAQTPWIGALIVLVAFLLMGVSGRLDKPVRIALE"
     gene            13945..14859
                     /locus_tag="OPY25_003275"
     CDS             13945..14859
                     /locus_tag="OPY25_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0928811.1"
                     /translation="MKATSEELAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQQILQEMAAAETEIMESRNTPRGLLRIDAATP
                     VMLHFLMPLIKPFRERYPEITLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
                     TSYRKVIASPDYIARFGKPESVEELKQHLCLGFSEPISLNTWPIACSDGQLHEIECGI
                     SSNSGETLKQLCLNGNGIACLSDYMIDKEIARGELVELLADKRLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEYIRTAPAGAVKEG"
     gene            complement(14880..15683)
                     /gene="dkgB"
                     /locus_tag="OPY25_003276"
     CDS             complement(14880..15683)
                     /gene="dkgB"
                     /locus_tag="OPY25_003276"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HCS0928812.1"
                     /translation="MTIPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAA
                     VGQAIAESGVPRNELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPG
                     DAVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADHIATNQIELSPYLQ
                     NRKVVDWAKAHGIHITSYMTLAYGKALKDEVIARIAVKHNATPVQVILAWAMGEGYSV
                     IPSSTRRENLASNLLAQDLHLDAEDKNAIAALDCNDRLVSPEGLAPAWD"
BASE COUNT         3846 a         4344 c         4179 g         3476 t
ORIGIN      
        1 gggacataca tcgtatttac tgccgccgcc ccctacattc cgctttttga gcaacatggg
       61 aaagacgata tcgcgctcag tcttgttcgc cacgaagagg cgtggtggat tgttaatcac
      121 tcggatgaac tgtgctgtgc cgtcaatgag caggtgatgg aacctcatca ccgtatgcgg
      181 ctgaatgatg gagatacgat tgaatggggt ctgtcatcct ggtgccttgc ccgcaccaat
      241 gatgagtccc gtcccgatgt ttcgtttcct cagttggttc agtcatctga atccgttgct
      301 gagtacctgg atctggactg gtttaaacaa caacagctca atccgcagaa cccgttcgat
      361 attattcccg tccgggaaac cgcgccctct tacaccggcc atgaagcgga tagcacgcta
      421 caccagcttt accaggaata tcagcaggcc ttgcggccct ccgggcagga aaagcccctc
      481 cgtcctaaac cgtttccccg aaatgaagac gctgtcaccc aggatttgac gtcgttatac
      541 gataaaaagg gcgataccga cacgttacag gatatggtgg caggcgcgcc cggtattgat
      601 gccattctgg atacgctgga cacgaccggt gagggtgaaa tgcactggct ggcgatggaa
      661 tcaatgcccg atatcctaca actgctctcg ccggaaatgg gggggaaaac cgcacatagc
      721 gagatactgc ccgatctgac ccgccgcgag catcgtatta ttggcatcga tagccactac
      781 cgaatcactc cgacacagaa aaatggaaat accgcccatg aaaaaaactg acacgcttcc
      841 tgctaccctg tccgcgctgc tacaggaata ctctattgcg gaggggattc agatggcgga
      901 gcagcaggtt cgggaaaatc cggcgaaggc gctctgccgc cacagcctgt ttcagttgct
      961 gtgtgtggcc ggagactggg cgcgggcgct acaccagctt cagctctgtg ccaggatgga
     1021 ggcaaattat acccaggagg cccggctgta ccgggagctg gtttgctgcg aaatgttccg
     1081 ccacaccgtt tttcagggtg aacaacgacc cggttttctt ctgccgcagc ccgtttgggt
     1141 ggagtcactg ctggcggcac tcgcctgtca tgacgatacc ggtgaggttg ataaacaccg
     1201 taataccgca ctggaagcca taacagacac gggcgggcag tggaacggcg gcgcatttga
     1261 ctgggcgagc gacagcgatt cccgccttgg cccggtactt gagctggtca ccggcggcgt
     1321 gtatatctgg ctaccgtttt cgcaaatacg ctcgctggaa tcgccgcaac cgacgcgcct
     1381 gaccgatctg ctgtggaaac ccgttaatat caccctggtg aatggcgata cgcacggtgc
     1441 ctggctcttt acccgttaca gcggttcgga aagtgcatct gacgccctgc gtctgtgccg
     1501 ggaaaccgcc tggcaggacg gccccggcga aaccaccgtg cgagcgctgg ggcagaaagt
     1561 gtggctgacc agccacggcg atatcagcct gctggacatg acccattgta cctttcatgc
     1621 tcaggaaaac gatggcgcat gagcacgtct cgttttacac ccgctaacca cctgctgcct
     1681 acgctgtttg atcggctgtg tgacaatgct ccgtatcaga aaattgaccg ggatatcagc
     1741 gtcacgccgg tacaactgaa ggagatcatt cgtcgggatc tctccttttt gctcaatacc
     1801 attagccacg agggtgacat cgacgcccgg cgctatccgc aggcggcggc gtcagtgctc
     1861 aactatggcc tgccgccgct ggcgggcagc tttatgtatg agcacaagtg ggacgatatc
     1921 agcgaggcga tccggcgcgc cattatccgt ttcgaacccc ggctgaacgc cgccacactc
     1981 agggtcacgc ccttgctcga tgaagcccgg cagggtagct ataacacgct acagtttgaa
     2041 attcgcggac aaattctgac gcagccgtat cccacggagt ttctggtacg cagcgcgctg
     2101 gatatggagc tgagccgcat tacgttcttt taatacaggg cattattcat ggatccacgg
     2161 ctactggagt attacaaccg cgaactgagt tacctgcggg agaccggtgc tgagttcgcc
     2221 accctccatc ccaaaattgc cgcccgactg gggatgcagg gaaccgatat tgccgacccg
     2281 tatgtggaac gcatgatcga ggcgttcagc tttctgagcg cccgcactca gctaaaaatt
     2341 gacgccgaat ttccccgctt cacacagcgg ttactggaag tcgtcaaccc caattacgtc
     2401 acccccacgc catcgatggc agtggtaaag ctgtatcccg atacgcagga aggcgacctg
     2461 gcgaaagggg tcaccgtgcc gcgcgatacc gcgttcgttt cccccatccc ggaaggcgaa
     2521 aataccgcct gccagtttcg cagcagccag gacgtcacgc tgtggccgct gtccatcgag
     2581 gaggtacgcc tgaccgccgc gccgccggat atgcccgccc tgcaccgcta tctgccgcct
     2641 aatattcatg tcgccggggc attgcgcatc accctgcgaa ccttcgggga actggctttc
     2701 agcgagctgg ccggtccggc acggctgccc ttttacctct gcggcgaaga acgcattgcg
     2761 tcacacctgt ttgagctgct acataccagc gccgtcgcca cactggccgg agaacccggt
     2821 cactttgacg gcgaactgaa tgtgaatctt caacacccgg tggcgcacga agggctggag
     2881 ccagggcagg ggctgctgcc gctcgcctgg aacgtgtttc atgggcataa tctgctgcat
     2941 gaatttttcg cctgtccgga acggttttac ttcttcaccc cgaccggatt gtctgccggt
     3001 ctacaaaagg tgcagggcaa tgtggcggaa attgttatac tgcttaaccg cctgccgccg
     3061 gactggctga ttcatcagac ggacgccgca cagttcagcc tgttctgtac gccggtgatc
     3121 aacctgtttc cccgcaccac cacccggatt gaagtcactc acagcgtgac ggaacagcat
     3181 ctggtggtgg atcgtacccg tccgctggat tacgaggtgt tttctgtcca ggaagtcgaa
     3241 ggcctggaag cggaaaccac acggaagatg atttttcgtc cgctgtatca cacccgtaat
     3301 aatgacgaag gcaaccacgg gcgttatttt tcactgcgtc gtgagccgcg ccgatcgtca
     3361 gaaagcgccc gccgctatgg cacccgaacc ccctataccg gctcggaagt cttcctctcg
     3421 ctggttgatc agcatgaagc gccctacccg gaaaatctgc gccatatcac cgtcacggca
     3481 atggtgacta accgcgatct gccctgcctt attccacgta atggccggga tgatctgacc
     3541 gtagatgcgg cgattccggt ggcgggcgtg ggtcttatca gaccgccgcg cccgccgcag
     3601 ccgccgctgg ctgaacgcga aatggcctgg cggctgatcc ggcagttgtc gtttaattat
     3661 ctgccgctgg ccgatctgga tcaccgcacc ggcggccagg cgctgcgcga tctgctgaac
     3721 ctgtttatcc cggctcacga cagcccgcag tcgcgccagg tgcgcagcct gattggctgc
     3781 aaaaccaccc cggtgacccg ccgcctaccc ggctccggcc tgttggtcta tggccggggc
     3841 gtcagttgcg aactgaccgt ggacgaagaa ggattttccg gtatcagtcc ttacctgttc
     3901 ggtctggtgc tggaacacta tattgcccgc catgtttcca ttaatacctt ctcgcagatg
     3961 acactgcact cgatgcaacg cgggcatgtc atgacctggc cggtcagaac cgggcaacgg
     4021 gggagcgtat gaccggcgct ctcgaccagg cgcagaaagc cccctggcgt tacggattcc
     4081 tgaacctgat gcgacgcgtg gatgcccagc tctgtgatac tccggcaggc agtatctggc
     4141 agcctcggat ggaaaaattc cgtctgggac agacgccgac gatgaccttt gcaccacggg
     4201 aaatcgccca ggtcagctgg caggatggac gcctgcacct gagcctgtac agcctcggac
     4261 tatgggggcc aaacggcccg ttgccgctgc actataccga gctggcgcta aatcgctcag
     4321 agagtcgtca cgatccgacg ctggttcatt tttccaatat ttttcactac cgctggctga
     4381 cgcagttctg gcaggcatgg cgcagcggcc agtccgctgg tggcgggctg gacaaaccgg
     4441 aacacgaccg ttttgcgttt tatatcgcca gtatcagcgg gcaggatcta cgggaaagcg
     4501 ccgaaagccc gctgtcagat catgttcgcc tggcggcctc cgcccatctg gtacgcgagt
     4561 cgcgcaatcc tgacgggctg gccgccacgc tggcgcacta tttcagcgta ccttttgcgg
     4621 tgaaagagtt tgccctgcac tggataacgg tggcgaacga tgaaatcacc cgtctgggca
     4681 cgcccgcgca gtcttcggtg ctgggcaacg gggcgcttat cggccaggcc gtaccggata
     4741 tgcagtacaa attccggcta attatcggcc cgctcacgct ggaggattac ctgcgttttc
     4801 tgcccggcgg caacaatctg cccgtgctga cagaactggt gcgtacgttc atcggttttg
     4861 aatattgctg ggaaattgag ctgcagttga agccccatgc cgcaccgcct gcggtgatcg
     4921 gcggcgcgca gcggcttggc tggacggcct gggcaggtaa agccatgcat gaccgtccgg
     4981 tgaccggcat gatttttgaa cctgaacacg gcttaaccca ctgagagtaa tgatatggac
     5041 atgtccctga ctaaaccggt aagcgcggaa caaccctgcg gccccgatcc ggagtacgat
     5101 ccggaatacc tgctgctgtt cagccgcgcc gccccccagg cggaggcgca atatggtgat
     5161 tttgtcagta cgccggaagc cgtgaactgg ccggaaattg agcgtgatgc gcgccgtctg
     5221 ctcacgcgca gtaaggatat ccgggtgttg atcctgctgc tgcgcagtcg catccagcag
     5281 gctggcgcac agggactggc ggaaatgctc acacaactgg cagaactgag cgtaatctgg
     5341 tctgatgcac tccatccaca gctgcttacc ggcgaaggcg catccgcaga atctattgaa
     5401 gatgcggcgc tggcgcgcag taatgccctg gcggcgcgct ggatcacgaa ggcgtgatgg
     5461 cagacattcg cggtatcacg ctgtcaaaca gtgccgccct gcacctgcag gtacgggacg
     5521 tggagcgcgc gttatccgcc cctcgcccgg ctgatgcgct ggcccccgaa tccgtccgcc
     5581 agcaactggc agacctcgaa gcccgtgggg cattaccgct agcggcgttt cgcgaagcgc
     5641 aggaaagcgc agaacgcctg caagtgtggg cgcgtgagac attaggcgat ctggctccag
     5701 atttttcacg cctgcggcag ttgttagcgc tgctgcctga cgtggtacag acaaccacgc
     5761 cggaaatccc tccgtcgcca gcgccagcgc cagctcccgc aggcacggtt atggataatg
     5821 ccattcctgc acgggcagag gatgtgccgc ctgtcaacgc gccacccggt atatctatcc
     5881 cacacaatgc tgaaccgggg ccaattcgcg atcgtaatga tgcgctggaa cgcctgcggt
     5941 gcattcgtcg ctggtttgag agcagtgaac ccagcagccc gaccatccca ctattacgtc
     6001 aggctgaaag actggtggga aaacggttct cggaggtgat caatgagatc ccggtggagt
     6061 tgctggagaa gtgggatgcc ctggagtgat gatgcgcatg tctggcggtt ctccgtgatt
     6121 atctgagtga catcaacatt actcggtctg cttctgcgct gaacatgtcc cgatcccggt
     6181 taagcaccgc catgaggccg cgccttaaat gtcagtggga caaaataacc atgacagtga
     6241 aagaagtggc ggtaatatcc tgttcgtcat ccaggcgtag gcccatttgc gccagattcc
     6301 acgatagacg gtggaacttc ttgaagacga aaaaaaaccg tatccctttt acagtgatac
     6361 ggttttttta cttcacagga tgtataaaaa caccctgaga tttgtatctg gcggaacgga
     6421 cgggactcga acccgcgacc ccctgcgtga caggcaggta ttctaaccaa ctgaactacc
     6481 gctccgtgat gttcccgctg ggaacgaggc gaatattacg gtttgcggtg tcgcccgtca
     6541 acgctttttc tcaccttttg aatcagttgc tgcaaaaatc gcccgaagga tgatttttat
     6601 agcctaaaaa ggaataaatt atgcccgcca aaggcaactt ccgccctttt tctgcaccag
     6661 atcaagccgc gattcatgcg cagccagctc ttcctcagag gcaaaaacga cccgtaaccg
     6721 gctggcctgg cgaacgattc gctgaatggt cgcttcacct tgctgccgtt gcgtctctcc
     6781 ttccatcgca aacgtcatgg acgtttgtcc gcccgtcatc gccagataca cttcggcaag
     6841 gatctgggca tcgagcaatg cgccgtgcaa agtacgtttg ctattatcta tctcataacg
     6901 cgaacacagc gcatcaaggc tgttacgctt gccggggaac attttccgcg ccaacgccag
     6961 gctatcggta actttgcaga aagtattggt tttaggaata tcgcgtttaa gcagaccaaa
     7021 ctcataatcc ataaagccga tatcgaacga tgcgttatgg atgaccagct ccgcgccgcg
     7081 gatataatcg agaaactcat cgaccacatc agcaaaaacc ggcttatcca gcagaaactc
     7141 atcggcaata ccgtgtacgc caaacgcttc cggatccacc agccgatccg gcttcaggta
     7201 aacatgaaaa ttgttgccgg tcagacgacg gtttatcacc tcaaccgcac cgatctcaat
     7261 aatcttgtga ccttcatagt gcgcgcctat ctggttcata ccggtggttt cggtatcgag
     7321 gacaatctgt cgtgtaattg cagtgctcat atcggtcatt tatgtcagac ttgcgttttg
     7381 ttatcgattt caattacagg aagtctacca gagatgctta aacaggtaga aattttcacc
     7441 gatggctctt gcctggggaa tccagggcct ggtggttatg gcgctatctt acgctatcgc
     7501 ggtcatgaaa aaacgtttag tgaaggttac acgctgacca ccaataaccg tatggaactg
     7561 atggcggcga tcgtcgcgct tgaagcgtta aaagaacatt gcgaagtgac attgagcacc
     7621 gacagccaat atgtgcggca aggaattacc caatggattc ataactggaa gaaacgcggc
     7681 tggaaaacag cggaaaagaa acctgtaaaa aatgtcgatc tctggaaacg tctcgatgct
     7741 gcgttaggcc agcatcagat caaatgggta tgggtcaaag gccatgcagg ccatcccgaa
     7801 aacgagcgtt gtgatgaact ggcgcgcgcc gcggcaatga atcccacgca ggaagatagt
     7861 ggctaccagg cagaagctta gccatccggt ttgcgatatt gccgggtggc gccaacggtc
     7921 tggcggatag gggttttact tttattatgt cgcagcggat taagcgtaag cggaatggtc
     7981 cgcttacggg ccacaataag ctgtaaacag cccagcgccg ggatatgcgt atttaaaagc
     8041 cgccctccct gctttttcca gggtaagaca tgaaaacggc tataatgtag cacttcgaaa
     8101 ttgagtaaag acagccagtc cagttgccgc ataagggtaa acatccgact attatagggc
     8161 ggtgttttac gtaaaacgag taccagttta cgtaacccca tcaaactcag cgggttaaat
     8221 ccactgatga ccagccaacc gtcatcaatc aatacgcggt cggcttcccg caataaacgg
     8281 tgcgggtcgg tacaccacgg caaagtatgc gccagcagac aaacatcgac ggatttatcc
     8341 gcaaaaggaa gatgtagcgg atcggccaga acctgcatcg gcgacccctg cgatgaaaca
     8401 ttcacttgat gggagaccgc gcacgcttcg gaattgattt ctgcgcttaa attaccgatt
     8461 ttaagcaaat ggaaaccata catttttgca aaccacggat ttagctgctg ttccagcgcc
     8521 tcacggtagt aattgcccca gggcaactca ccccaacatc cgggcgcaac gacagtttga
     8581 gagagccttg ccggtttcat cgcaaccttc cgctaattat ttgagaggta atatatgaat
     8641 cttaacagta ttcccgcgtt tcaggacaat tacatctggg tgctgaccaa tgatgaaggc
     8701 cgctgtgtga ttgttgatcc cggcgaagcg gcccccgtct taaaggccat tgctgcacat
     8761 aagtggatgc cggaggcgat ttttctgacg catcaccatt acgaccatgt tggcggagtc
     8821 aaagagctgt tgcaacactt cccgcaaatg acggtttatg gaccggcgga aacgcaagac
     8881 aagggagcaa cccatcttgt tggcgatggc gatactattc gcgttttagg cgagaaattt
     8941 actctttttg ccacgccggg ccacacgtta ggacacgtct gttactttag ccatccttac
     9001 ttgttctgcg gcgacacgct gttctctggc ggctgtggta gattgtttga aggcacgcca
     9061 tcacagatgt atcagtcact tatgaaaatt aactctctgc ctgacgacac actcatttgc
     9121 agcgctcacg aatacacttt agctaacatt aagttcgcat tgagcatact tccgcacgat
     9181 tcgttcataa atgaatatta tcgtaaagtt aaagagttac gtgtaaaaaa acaaatgaca
     9241 ctacccgtta ttcttaaaaa tgagcgtaag attaatcttt ttttaagaac tgaagatatt
     9301 gatttaatta atgaaataaa caaagaaaca atattgcaac aaccagaagc gcgttttgca
     9361 tggttaaggt caaagaaaga cacgttctga taattcttac ttgtcattcg ctaacttcgc
     9421 cgttatgatc ggtcgtcttt taagcaacta ttgacacaca catgaaggca aaagcgatat
     9481 tactcgcctc tgtcctgctt gtggggtgcc agacatctca gaacactggc aacgtccaac
     9541 agcacgcaca gagcctttct gcagctggtc aaggggaagc aggaaagttt acgagtcagg
     9601 cacgatggat ggacgacgga acgtctatcg cgccagatca ggacttgtgg gctttcattg
     9661 gcgacgagct aaagatggga attccggaaa acagccggat tcgcgaacag aaacagaagt
     9721 atttacgcaa taagagctat ctccacgatg taactttacg ggcagagccg tatatgtact
     9781 ggatagcggg gcaggttaag aaacgtaaca tgcctatgga gctggtacta ctacccatag
     9841 tggagagcgc ttttgatcct cacgcaacgt ctggcgccaa tgccgcaggc atctggcaga
     9901 tcataccgag cacagggcgc aattatggtt taaagcagac ccgtaattat gacgcgcgtc
     9961 gcgatgttgt agcctctacg accgccgcgt tagacatgat gcagcgtctg aacaaaatgt
    10021 ttgacggcga ctggctgtta actgttgcag cgtataacag cggcgaaggc cgtgttatgc
    10081 gggcaattaa agcaaacaaa gcgcgtggaa aaccgacgga tttctggtcg ctttctttgc
    10141 ccagagaaac gaaactctac gtacctaaga tgctggcatt gagtgaaatt ctcaaaaaca
    10201 gcaaacgcta cggcgtacgt ctgccaacaa cagatgaaag ccgagcgctg gcacgagttc
    10261 gtttaaacag tccagttgaa atggcccagg ttgcggatat ggcgggcatg tctatcagca
    10321 agctgaagac gtttaatgcc ggtgtaaaag ggtctacctt aggcgtaagc ggtccgcaat
    10381 atgttatggt gcccaaaaag catgccgagc agttgcgtga gtcgctggct tccggtgaga
    10441 ttgacgccgt tcagtcccaa ctgatcgccg acaatacgcc gttgaatagc cgtagctata
    10501 aggtgcgctc tggcgatacg ctttccggta ttgcttcgcg gcttggcgta agcacgaagg
    10561 acttgcagca gtggaacaac ctgcgtggtt cccgcctgaa aatcgggcaa agcctgaccg
    10621 tgggcgctgg cagcagcgcg caacgactgg caaacaatag cgatagcatt acctatcgtg
    10681 tccgtaaagg cgattcgctt tccagtatcg ccagacgtca cggggtgaat atcaaagatg
    10741 tgatgcgctg gaaccatgat acggataatc tacaaccggg cgatcagctt acgttgtttg
    10801 tgaaggacaa tagcacgcca gactcctgat attgtccgac gaaaaagcca aaaggcgccg
    10861 cttcccccgg cgccttttaa attgttatac cgctttatgc gcttccagca tgatagtatc
    10921 gctgctaaac gagccgtcat cctgcaactc aaaataacgc ttcacctcta ccggggcgct
    10981 cgcctgatat aatcgaatcg cctcaaccaa cggcgctggc gtacgcatcc gcgttaccca
    11041 tgagcgaaac tccagcgata aacgatcggt tatcacggta ttcgttacca gcatcgcgtt
    11101 attgaccatc gccagccatt caccactgga atagttacgg acatgcgacg tgtcgcgtaa
    11161 cgcctccacc gtttgcagcc agatatcgcg tacaggatgt ccaggcgaca tgacatccat
    11221 gataatcagc acgccgccgg gttttaatac acgataaacc tcacgcaatg cctgaccaac
    11281 gtcgtgccag tgatgcgcgg aatagcggct aatcaccacc tcaaacgatg catcttcaaa
    11341 gggcagtttt tcggcatagc cttgccggag agtaatatta cttaaatgtc tttcttccgc
    11401 cgctccagcg acaacctcaa gcatgctggc ggataaatcg tatgccacga ccgaattgac
    11461 atgttgcgca gcgacaaaac tcgcgtgtcc agccccacat cccatatcca gtacgctcgc
    11521 gtgggaaaaa tcagacaacc tttgcgccag ccgcgctaag tcacgacccg ctgcgtgaac
    11581 ggcgctatgt aaataggcgt tcgcctgtga accaaactgc ttttcaacat tgtcatggtg
    11641 ggaatgcgtt gtcatggtag tgcccttctg ttatgagaaa aatagagggc agcacccgca
    11701 gaggcctgcc ccacggcaga cctgactcac ctttattgct caggtttgcc gggactgaat
    11761 tcaacgagta gcggattgtg atcggaagcg cgcgtcacca gtacggaggc ttcattcacg
    11821 tttaaaccac gataaaaaac aaaatccagc ggtcgtccaa acgcacgacg gcgttgatcg
    11881 tcagtgaaac gcacctggcg cagcgacatc tcacgtgcaa agcggtacaa cgcattcata
    11941 cgtgggcggc tccaggcatt aaaatcaccc gccataatga cagggccgct atggtgcgca
    12001 atctggtcgc cgatcggaag taactgctta ctgtatacgt ccacgcccag actaaaattt
    12061 accgcatgaa catttactac cattaataaa cgggtatccg gcaagggata taccgtcacc
    12121 agggctgatt tcgccaaacg taaaattggt tctctttccc gtaaagggca gcagtaaaca
    12181 ggatgggcgg cagaaagcgt cataacgcca gacgggtgct gaggtaatac aaaagcggga
    12241 acctgatcgg cggcaagata gttagcggtg gcaaactgta ccagttcagg cgtcgtctgg
    12301 gcctcctgca acaggaccag atgcgcatct ttgccgtagt tcttcagcac cgataaccat
    12361 tcggctcgct gctgcttgaa tatattccac acgaggatac ggatccgctc ttcactgctt
    12421 agcggttccc cggcgggcaa tgcctggcca atgctcgcaa acgaccctag cggcaaaatc
    12481 cgctcggcgg gctgtccggc aacatagcgc atcgcatagg tgttttttcg cacttttgac
    12541 tttcaaacct ctgtaacgtc aaccagtcct caaccggact ggttcttctg ttatagggat
    12601 tttagcactc actttcaacg aacaattgca gtttgttttg taagtaggcg cttacatcaa
    12661 taatttactc cagagcaatg cgcacaggtt tatcaagacg tccgctgacg cccatcagca
    12721 gaaaagccac cagaacaatg agggcgccaa tccacggcgt ctgcgccaaa ccgtaatgcg
    12781 ccaccgtttg tccgccaatc acggaaccca gcgcaatacc aatgttaaac gccgcaatgt
    12841 tcagacctga cgccacatca acggcattag gcgtgaattg ttccgctttc tgtaccacgt
    12901 agacctgcaa ccccggtacg ttaccgaagg caaagatccc catcaccaga atggtagcca
    12961 gcgcggcata ctgcgtggag gccgtcacct ggaagaccat cagcagaaca aacagcgcgg
    13021 cgaaaatgaa tttcagagcc ggcacggcac catgcttatc cgccagttta ccgccccaga
    13081 tattgccgat agccactgat acgccataac ccagtaggat ccagcttact gctgccggag
    13141 agaatcccgc cagatcctgc atcatcggcg ccaggaaggt gaatgccgtg aataccccgc
    13201 cgtagcccag cgccgtaacg gcgtaaatca gcagcagacg aggatgagtc agtactttca
    13261 cctggtcacg aatgctggcg gccgcccgac caggaatatt ggcagggatc agcagttgac
    13321 tgctcatcag cgcaatcacg cctaacagtg ataccgcaag gaaggtctca cgccagccaa
    13381 aatgctgacc gataaatgtc cccagcggaa cacctgttac cagcgctact gttaaaccac
    13441 caaacataat agcgatagca gaagccgctt tctctttcgg caccagactt gtcgcgatgg
    13501 tagagccaat cgagaagaac acgccgtgcg ccaggcccgt cagcagacgg gcggcgatta
    13561 atgtcatata gcccggagcc tgccacgcca gcaaattccc cgccgtaaac aagaccatca
    13621 gcgcgaccag taactgttta cgcggcaggc gtccggtcag agcggttagc accggcgcgc
    13681 caatagccac acccagtgca tagattaaaa ccagcattcc ggcagaaggt aacgagacag
    13741 ccagttgttg tgcaatggtc ggcaccaggc cgacaatcac gaactcagtc gtgccaatag
    13801 cgaaggcact tattgtcagt gcaaataaag cgagaggcat acataactcc ataacagcag
    13861 taatcagatg acacgcagta tgccaggatg ttttaatgac aaaaatagcc aaaatataaa
    13921 tttaattttg ctgcaggagc agaaatgaaa gccacctccg aagaacttgc aatttttgtc
    13981 gctgtcgtgg aaagcggcag cttcagccgg gcggcagagc agctcggaca ggccaattcc
    14041 gctgtcagtc gggcagttaa aaagctggag atgaagctcg gcgtcagtct gcttaatcga
    14101 acgacccgac agttgagcct gactgaagaa ggagagcgat acttcaggcg tgtgcagcag
    14161 atactgcaag aaatggctgc cgcagaaacg gaaatcatgg agtcgcgtaa taccccacgc
    14221 ggcttactgc gtatcgatgc ggcaacgccg gtaatgctgc atttcctgat gccgctgatt
    14281 aaaccttttc gtgaacggta tccggaaata accttgtctc ttgtctcctc agaaacgttc
    14341 atcaatctta ttgaacgaaa agtggatgtt gcgatacgcg caggcacgtt gacagattca
    14401 agtctgcgcg cacgtccgtt atttaccagc tatcgtaagg ttatcgcctc accggattat
    14461 attgcccgtt ttggcaagcc tgagagcgtt gaagagttaa aacagcatct gtgcctgggg
    14521 ttttctgaac ctatctcgct caatacctgg ccgatagcct gtagtgacgg acagctccat
    14581 gagatcgaat gtgggatttc gtccaacagc ggggaaacgt taaaacaact ttgcctgaac
    14641 ggtaacggca ttgcatgtct ttcagattat atgattgata aagagatcgc gcggggagaa
    14701 ctggtggaac tgctggccga taaacgtctg ccggtagaaa tgcctttcag cgccgtttac
    14761 tacagcgatc gcgccgtcag cacacgtatt cgggcattta tcgacttttt gagcgaatat
    14821 ataagaacag cccccgcagg agctgtgaaa gaggggtaaa ggtacaaagg atcgggtaat
    14881 taatcccagg caggagccag tccttccggg ctaaccagac gatcgttgca gtccagcgcc
    14941 gcgatcgcat ttttatcttc ggcatccaga tgcagatcct gcgccagcag gttgcttgcc
    15001 aggttttcac gcctggtgga tgaagggatc accgagtaac cttcgcccat tgcccatgcc
    15061 agaataacct gcaccggggt cgcattatgt ttaaccgcaa tgcgcgcaat cacttcatct
    15121 ttcagcgctt taccgtatgc cagcgtcatg taagaggtga tatggatacc gtgcgctttc
    15181 gcccagtcaa ccaccttacg attctgcaga tacggagata gctcaatctg gttggtggcg
    15241 atatggtctg cgcccaccgc ggcaatagcc ttttccatca acggaatagt gaagtttgag
    15301 atgccaattt cgcgagtcag cccttgtttt ttagcttcca gcaatgcctg cataaattct
    15361 tcgacagaca cggcatcacc cggagatggc cagtggatca gcgtcagatc gacataatcg
    15421 gtacgcagtt ttttcaggct ctctttcagg cttgggatta gcttgtcttt gctaaggttt
    15481 tcaatccaga tcttggtggt gatgtacagc tcattacgcg gtacgccgct ctcagcaatc
    15541 gcctgtccaa cagccgcttc attatcatag atttgcgcag tgtcgacagc acggtagccc
    15601 agttcaagcg ccgttttcac agaagcgata accacgtcgt ctttcaggcg aaaagtacct
    15661 aaaccgaatg cagggatagt catagaattc ctctttttaa tcactatgtt cgttaactga
    15721 ggggattatg accttcagcg ctttgtagaa aaagagcgag aaatgcagag gatttttgcg
    15781 aattgagcaa taattaaatc gcaggcaaag aaaaagccct gagctaatgc tcagggctct
    15841 taata
//
LOCUS       DAJVKX010000103        15767 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.103, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000103 DAJVKX010000000
VERSION     DAJVKX010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15767
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.103"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(291..1097)
                     /gene="trpA"
                     /locus_tag="OPY25_003277"
     CDS             complement(291..1097)
                     /gene="trpA"
                     /locus_tag="OPY25_003277"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HCS0928813.1"
                     /translation="MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAG
                     ADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMY
                     ANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADD
                     DLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPE
                     QVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAELRSFVSAMKAASRA"
     gene            complement(1097..2290)
                     /gene="trpB"
                     /locus_tag="OPY25_003278"
     CDS             complement(1097..2290)
                     /gene="trpB"
                     /locus_tag="OPY25_003278"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HCS0928814.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQ
                     FADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILD
                     KEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALE
                     AFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            complement(2300..3658)
                     /gene="trpCF"
                     /locus_tag="OPY25_003279"
     CDS             complement(2300..3658)
                     /gene="trpCF"
                     /locus_tag="OPY25_003279"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HCS0928815.1"
                     /translation="MQTVLAKIVADKAIRVEARKQQQPLASFQNEIQPSTRHFYDALQ
                     GARTAFILECKKASPSKGVIRDDFDPARIASIYQHYASAISVLTDEKYFQGSFDFLPV
                     VSQSAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLSAVAHSLKMGV
                     LTEISNDEERERAIALGAKVVGINNRDLRDLSIDLNRTRQLAPKLGHGVTVISESGIN
                     TYGQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVCGLTRAQDAKAACDAGA
                     IYGGLIFVPSSPRAVSVEQAREVISGAPLQYVGVFKNADIADVCQKAAVLSLSAVQLH
                     GSEDQAYVNALREALPRNVQIWKALSVSNALPARDYHHVDKYIFDNGQGGSGQRFDWS
                     LLQGQPLDDVLLAGGLAADNCVQAAQVGCAGLDFNSGVESQPGIKDARLLASVFQTLR
                     AY"
     gene            complement(3662..5257)
                     /gene="trpD"
                     /locus_tag="OPY25_003280"
     CDS             complement(3662..5257)
                     /gene="trpD"
                     /locus_tag="OPY25_003280"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HCS0928816.1"
                     /translation="MADILLLDNIDSFTWNLADQLRTNGHNVVIYRNHIPAQTLIDRL
                     ATMKNPVLMLSPGPGIPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLANPLPVARYHSLVGSNVPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPTNTLQPILEKLYQAQTLTQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQDQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGQEDLKANA
                     QTVLDVLRNGTAYDRVTALAARG"
     gene            complement(5257..6819)
                     /locus_tag="OPY25_003281"
     CDS             complement(5257..6819)
                     /locus_tag="OPY25_003281"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component 1"
                     /protein_id="HCS0928817.1"
                     /translation="MQTPKPTLELLTCDAAYRENPTALFHQVCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSDNGASLLPLLDTALPAGVENEVLPAGRI
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQGVVNIPTQEREAMFFGGLFAYDLVAGFEA
                     LPHLEAGNNCPDYCFYLAETLMVIDHQKKSTRIQASLFTASDLEKQRLNARLAYLSQQ
                     LTQPAPPLPVTPVPDMRCECNQSDDAFGAVVRQLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDAASRQIEIYPIAGTRPRGR
                     RADGTLDRDLDSRIELDMRTDQKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIADAEGQRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGIVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     misc_feature    complement(6842..6937)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            complement(6914..6958)
                     /gene="trpL"
                     /locus_tag="OPY25_003282"
     CDS             complement(6914..6958)
                     /gene="trpL"
                     /locus_tag="OPY25_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HCS0928818.1"
                     /translation="MAATFALHGWWRTS"
     gene            7080..7961
                     /gene="yciV"
                     /locus_tag="OPY25_003283"
     CDS             7080..7961
                     /gene="yciV"
                     /locus_tag="OPY25_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HCS0928819.1"
                     /translation="MGAALSDTNYAVIYDLHSHTTASDGLLTPETLVHRAVEMRVGTL
                     AITDHDTTAAIPAAREEISRCGLALNLIPGVEISTVWENHEIHIVGLNIDIAHPAMRD
                     FLAQQTHRRQARGRLIAERLEKAHIPGAWEGALRLANGGAVTRGHFARFLVECGKATT
                     MAEVFKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYDLSAKWLKRLVA
                     HFADHHGDAMEVAQCQQSPNERTQLATLARQHHLWASLGSDFHQPCPWIELGRKLWLP
                     AGVEGVWQAWEQPQISQ"
     gene            7969..8589
                     /locus_tag="OPY25_003284"
     CDS             7969..8589
                     /locus_tag="OPY25_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCS0928820.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVDIVRKGGVIVYPTDSGYALGCKI
                     EDKGAMERICRIRHLPDGHNFTLMCRDLSELSTYSYVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGLRVPSNPIALALLDTLGEPMLSTSLMLPGSDFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQQPTTVIDLTNDSPVVLREGVGDVTPFL"
     gene            8690..9565
                     /gene="rluB"
                     /locus_tag="OPY25_003285"
     CDS             8690..9565
                     /gene="rluB"
                     /locus_tag="OPY25_003285"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HCS0928821.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEV
                     TPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDESKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRGLVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QIAGGRRSGGRNNNG"
     gene            complement(9652..10242)
                     /gene="cobO"
                     /locus_tag="OPY25_003286"
     CDS             complement(9652..10242)
                     /gene="cobO"
                     /locus_tag="OPY25_003286"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HCS0928822.1"
                     /translation="MSDERYQQRQQKVKDRVDARVAQAQEERGIIIVFTGNGKGKTTA
                     AFGTAARAVGHGKNVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWETQNREADT
                     AACMAVWQHGKRMLADPLLDMVVLDELTYMVAYDYLPLEEVISALNARPGHQTVIITG
                     RGCHRDILDFADTVSELRPVKHAFDAGVKAQMGIDY"
     gene            complement(10239..11000)
                     /locus_tag="OPY25_003287"
     CDS             complement(10239..11000)
                     /locus_tag="OPY25_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HCS0928823.1"
                     /translation="MHYQPKQDLLQNRIILVTGASDGIGREAALTYARYGATVILLGR
                     NEEKLRRVAQHIADEQHVQPQWFTLDLLTCTAEECRQVADRIAAHYPRLDGVLHNAGL
                     LGEIGPMSEQDPQIWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYATSKFATEGMMQVLADEYQNRSLRVNCINPGGTRTSMRASAFPTEDPQKLKTP
                     ADIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGIAQ"
     gene            11238..12284
                     /gene="sohB"
                     /locus_tag="OPY25_003288"
     CDS             11238..12284
                     /gene="sohB"
                     /locus_tag="OPY25_003288"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HCS0928824.1"
                     /translation="MELLSEYGLFLAKIVTVVVAIAVIVLLIVNATQRKRQRGELRVT
                     NLSEQYQEMKDDLAAALMDGHQQKLWHKAQKKKHKQEAKAAKAKAKLGDIATSDKPRV
                     WVIDFKGSMDAHEVNALREEVTAVLAVAKPGDRAVVRLESPGGVVHGYGLAASQLQRL
                     RDKNIPLTVTVDKVAASGGYMMACVAEKIIAAPFAIVGSIGVVAQIPNFNRFLKSKDI
                     DIELHTAGQYKRTLTLLGENTEEGRQKFREDLNETHHLFKEFVQRMRPALDIEQVATG
                     EHWYGQQALEKGLVDEINTSDEVILGLMEGREVLNVRYMQRKKLIDRVTGSAAESADR
                     LLLRWWQRGQKPLM"
     gene            complement(12326..12577)
                     /locus_tag="OPY25_003289"
     CDS             complement(12326..12577)
                     /locus_tag="OPY25_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HCS0928825.1"
                     /translation="MHKETQPIDRETLLLEANKIIREHEDTMAGIVATGVTQRNGVLV
                     FSGDYFLDEQGLPTPKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            12980..15577
                     /gene="topA"
                     /locus_tag="OPY25_003290"
     CDS             12980..15577
                     /gene="topA"
                     /locus_tag="OPY25_003290"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCS0928826.1"
                     /translation="MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNIN
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPT
                     SSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTL
                     PAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDN
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     SPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFV
                     DGKWVEGKK"
BASE COUNT         3609 a         4180 c         4459 g         3519 t
ORIGIN      
        1 agaaaatgct ttgcattgtt attaataaca agagtcacta tctgcggccc tggaaacgtt
       61 aatgcattgt ttgttgacat ttctttacat aaaggcgggg gaaattgacg tgaaaacgct
      121 aaatttttcg gcgtgattag gagttttctt agcaaaaatt gacttcagac tttttgaaag
      181 ctggacgggg aataacacca aaaagattga tgatgtacgc ctgaatcgtg attctggttt
      241 ggcgccaacc tctcattaag ccgccagcgt tatgctgacg gcttaacccg ttatgcgcgg
      301 ctggcggctt tcatcgctga gacaaaggac ctgagctccg ccaacatctg ttcgggagac
      361 gcgaggtttt tctcgataat cttgacaatg gctgagccgg agatagcgcc agccgccccg
      421 gcacgcacgg ccgcagacac ctgttccggc gaggagatac cgaagccctg taacgcaggc
      481 gcggcgtggt actctttaag cttctcaatg agatgatgca acggcaatgc gccacggttt
      541 tccgcgccgg tgacgcccga acgcgaaagc aggtaggtat aaccgcggcc gtaagatgcg
      601 acctggcgca gaagatcgtc atccgcattt ggcgggcaga tgaagatcgg cgcgatatta
      661 tgccgtaacg ccgcctggcg gaagggggcc gattcttcaa ccgggacatc tgcgaccagc
      721 acggaatcta cgccaacctg ttcacaacgg gcatagaacg catctatgcc gttattgaac
      781 accagattcg cgtacattag caggccaatc ggaatggtcg ggtgtttttc acgaatcagc
      841 gccagcattt caaaacactg agctggcgtg acgccagcgg cgaaggcgcg taagttcgca
      901 ttctggatgg tagggccatc ggccagagga tcggagaagg gaacccccag ctccagagcg
      961 tcggcgccag cgtcaatcag tgtgtcaata attttcagtg actgttcaat gccagggtcg
     1021 cccagggtca cgaaggggac aaaagcgcct tcccggcgat cgttgagttg ggcaaataaa
     1081 ttttcgtagc gttccatcag atttcccctc gcgctttcag gatatcgtgt acggtaaaga
     1141 tgtctttatc tccgcggcca gagagattga ccaccagcag ttgctctttt tccggctgct
     1201 cgcgcatcat tttcagagcg tgcgccaacg cgtgggagga ctccagcgcc gggataattc
     1261 cctcatggcg gcacaacgtt ttgaaggctt ccagcgcctc atcatcggta atggagacat
     1321 aatccgcgcg tccgatgctg ttcaggtacg catgttgcgg cccaacggac gggaaatcga
     1381 gtccggcgga aatggaatag gactcttcaa tttgcccgtc tgctgtttgc atcatcggcg
     1441 ctttcatccc gaaatagatg ccaacgcgac catgtttaag cggcgcacca tgctcgccgg
     1501 tttcaatacc gtgaccgcca ggttcaacgc ctattagccc gacgctggta tcattaataa
     1561 aatccgcaaa catcccgata gcgtttgagc cgccaccgac gcaagcgata acggcatctg
     1621 gcagacggcc ctctttgtcg aggatttgcg ctttcgtctc ttcgccaatc atgcgttgga
     1681 actcgcgaac gatggtagga tagggatgcg gtcctgccgc cgtgccgagc atatagtgcg
     1741 cggtttcgta actaccggac cagtcgcgca gcgcctcgtt acaggcatct tttagcgtag
     1801 cggagccgct atgaaccggg atgacctcag cgcccatcag acgcatacgg aagacgttcg
     1861 gcgactggcg ctcaacgtct ttggcaccca tatagatacg gcatttcaga cccagcaggg
     1921 cgctggcgag cgcagaggcg acgccgtgct gaccggcgcc ggtttcagcg ataatctcgc
     1981 ttttacccat ccgtttggcc agcagcgcct gacccagtac ctgattggtt ttgtgtgcgc
     2041 cgccgtgcag taaatcttcg cgctttaaat acaacgtggt acgcgtaccg gcggtaatgt
     2101 tctggcattt cgtcagcgcg gtggggcgtc ccgcgtagtt ttttagcaga tcggcgaatt
     2161 gcgcctgaaa ttcaggatct ttttgcgcgc tgacgaaggc ctcttcaagc tggttcagcg
     2221 caggcatcag gatctgcggc acatacatgc cgccgaattc accaaagtag gggttgagaa
     2281 gtgttgtcat gttttttcct taatatgcgc gcagtgtctg aaaaaccgag gccagaagac
     2341 gagcatcttt gatgcccggc tgtgactcca cacctgaatt aaaatcgaga ccggcacagc
     2401 cgacttgcgc cgcctggacg cagttatcgg ccgccagccc gcccgccagt aacacatcat
     2461 ccagcggttg cccctgtagc agtgaccagt cgaagcgctg cccgctgccg ccttgcccat
     2521 tgtcgaaaat gtatttatcg acatggtgat aatcgcgtgc gggaagggca ttgctaacgc
     2581 tcagcgcctt ccagatttgc acattgcgcg gcaacgcctc gcgcagcgcg ttgacatacg
     2641 cctggtcttc gctgccatgt agctgtacgg cagaaagcga caggacggcg gctttctggc
     2701 aaacatcggc gatatcagcg ttcttgaaaa cgccgacata ctgcaatggc gcgccgctta
     2761 tcacttctcg cgcctgctca acgctaaccg cgcgcggaga tgagggcaca aaaatcaacc
     2821 cgccatatat tgcgccagcg tcacaggccg ctttagcgtc ctgggcgcgg gtcaggccgc
     2881 agactttatt ttcgccaagc agcacgcgac ggacggcggc gttaagatcg tcatgcgcca
     2941 ttaacgcgga gccaattaaa aaaccgttgg cgaagtggct cagttcgcgt acctgaccat
     3001 aggtgttaat cccggactcg ctgatgacag tcacgccgtg gcccagtttt ggcgccagct
     3061 ggcgggtgcg attcaaatca atcgacagat cgcgcagatc gcgattgttg atacctacca
     3121 cttttgcgcc taacgctatc gcgcgctccc gttcttcgtc attactgatc tccgtgagca
     3181 cgcccatttt cagactgtgc gcgacggcgg agagttggcg atactgttcg tcatccagaa
     3241 ccgagagcat cagtaaacag gcatcggcct gatagtaacg ggcaaggtag atctgatagg
     3301 gatcgataat aaaatcctta cacagaatcg gctgcggcgc gctttggcta acgaccggca
     3361 gaaaatcgaa gctcccctga aaatattttt cgtcggtgag caccgagatc gccgaggcgt
     3421 aatgttgata aatactggca atacgcgccg gatcgaaatc gtcgcgaatc acgccttttg
     3481 atggcgatgc tttcttacac tccagaataa aggcggtacg cgcgccctgg agcgcatcat
     3541 aaaaatggcg tgtacttggc tggatctcat tttgaaaact ggccagcggc tgttgctgtt
     3601 tgcgggcttc tactcgaatc gccttgtctg cgacgatttt cgctaaaacg gtttgcatta
     3661 tttaccctct tgccgccagt gcggtgactc tgtcatatgc ggtgccgttg cgcagaacat
     3721 caagcacggt ttgcgcgttg gccttgagat cttcctgacc atgcagacgc atcagcatcg
     3781 ccacgttggc ggcgacggcg gcctcatgcg cggcatcgcc tttaccttgt aataaccgcg
     3841 tcagaatgtc acggttttct tccggcgtgc cgccagccaa ctgatcctga tggtaaggcg
     3901 tcaggccaaa atcctccgcc gtaagttgat agcttttaat ttcgccgtca tgcagctccg
     3961 cgacaatcgt cggcgcatgg agcgaaacct catccatgcc gccgctatgt accaccgccg
     4021 cgcgctgata gcccagtacc cgtaaggttt ccgcaatcgg cagcaccagt tccgggctat
     4081 agacgccaat caatgccagc ggcggatgcg ctgggttgat cagcgggccg agtacgttga
     4141 acagggttcg cgtttttaac tgttggcgaa ccggcatcgc gtgacggaat ccggtgtgat
     4201 atttcggcgc gaacaggaaa cagacgccca gttcatctaa cgcctgacgt gatttatcgg
     4261 cgttcatatc cagattaata ccgaacgccg ccaacagatc ggatgacccc gatttgctgg
     4321 atacgctgcg gttgccgtgt ttcgccactt tcagtccaca ggccgccgcg acaaaggcgc
     4381 tggcggtaga gatattgata ctgttactgc catcgccgcc ggtaccaacg atatccgcaa
     4441 acagatagtc cgggcgcggg aacggggcgg cattttccag caacgcagtg gcggcgccgg
     4501 caatttcatt gggatgctcg ccgcgaattt tcatgctcac cagcgcggcg gcgagctgtt
     4561 caggcttaag ttcgccgcgg acgaccgccg aaaacaactg atggctctct tgttgcgtca
     4621 gagtttgcgc ctgatagagt ttctccagaa ttggctgtag ggtgttggtc ggttccagct
     4681 tttgctgcgc ccaggctaat gtttgctcca gtagacgcgc gccctgtgtc gtcaggatgg
     4741 actcaggatg aaattgaaaa ccgcaaacgc gatccgcatc atgacgtacc gccatcacca
     4801 tgccgttgaa atgggcgtta atggttagcc cggcaggaac attactgccg accagcgaat
     4861 gataacgcgc gaccggtagc ggattcgcca gaccggcgaa catcgcctga ccgtcatgtt
     4921 caatgctgga ggctttgcca tgcaggattt ctcccgcctg accgacataa ccgccgtaag
     4981 cttcgacaat cgcctgatgc cccagacaaa tgccgatgat cggtaacttg ccgcgtagtc
     5041 gggtcagcag ctccggcata cagcctgcct cgctgggaat gcccggaccg ggggagagca
     5101 ttagcaccgg atttttcatt gtcgccaggc gatcgataag cgtctgcgcc ggaatatggt
     5161 tacggtaaat caccacgtta tgaccgttgg tccgtagctg atctgccagg ttccaggtaa
     5221 acgagtcgat gttatcgagc agcagaatat cagccatcag aaggtctcct gtgcatgatg
     5281 cgcggtggcg atagcacgca atacggcgcg cgctttatta cgggtttcat cggcttcaga
     5341 ctgcggaaca gagtccagca cgattccggc gcccgcctgt acggtggcga taccgttctc
     5401 caccagcgcg gagcggataa caatacaggt gtccagatcg ccgtgggcgg tgaagtaacc
     5461 gaccgcgccg ccatagctgc cgcggcgctg tccttccgca tcggcaatca actgcatggc
     5521 gcgtactttc ggcgcgccgc tcagggtgcc catgttcatg caggcgcgat aggcgtgcag
     5581 cgcgtcgaga tcgtgacgca gttcgcccac tacccgggaa accagatgca tcacgtacga
     5641 atagcggtca actttggtca gatcggcaac gtagcgactg cccggcgtac agatgcgcgc
     5701 caggtcattg cgcgccagat cgaccagcat cagatgttcg gaaagctctt tctggtcggt
     5761 acgcatgtcc agctcaatac ggctgtcgag atctctgtcc agcgtaccat cggcgcggcg
     5821 accgcgtgga cgggtacccg cgatggggta aatctcaatc tgacggctgg cggcgtcata
     5881 tttcagcgag ctttccggcg acgcgccgaa aagcgtgaaa tcattatcct gcataaagaa
     5941 catatacggg ctggggttgc tctttttcag cacgtagtag gcagccaacg gcgacgggca
     6001 gggcagtgaa aagcggcgcg acggcaccac ctgaaatatc tcgcccgcgc ggatggcttt
     6061 ttgcaactgg cgtaccaccg cgccgaacgc gtcatcgctc tgattgcatt cacagcgcat
     6121 gtccggcacc ggcgtcaccg gcaacggcgg cgcaggctgg gttaactgtt ggctaaggta
     6181 cgccaggcgg gcgttgaggc gctgtttttc caggtcgctg gcggtgaaca gactggcctg
     6241 aatacgggtg ctttttttct gatgatctat caccatcagc gtttccgcta aataaaagca
     6301 gtagtccggg cagttattgc cagcctcaag gtgtggcagc gcttcaaagc cagcgaccag
     6361 gtcgtaggca aacagaccgc cgaaaaacat agcctcccgc tcttgcgtcg gtatgttcac
     6421 cactccctgt aacaggcgga acgcatcaaa taccgacaga gagcataaac gggcgtcttc
     6481 atctaataat gggctgacgg gcggaaagcg tagaatgcga ccggcaggca ggacttcgtt
     6541 ctccacgcca gcgggcaggg cggtatccag tagcggcaat aacgaggcgc cattatcaga
     6601 taacgcctga atagtgacag tgtcacctaa agcggtaatg cgcagcgcgc tatctaccag
     6661 cagcaggctt tttaaatcgt ctttactgtc gatatccgcg gattccagca gcagcgttgc
     6721 cgggcgatcg ccgcagacct ggtgaaaaag cgccgttggg ttttcccggt aggcggcatc
     6781 gcaggtcaat agttcgagcg tgggttttgg tgtttgcatg gttattctca ttattttgtt
     6841 caaaaaaaag cccgcttaac aggcgggccg ggtatcgttt ggctgattac agctgttcat
     6901 acaccgcccg ctatcaggaa gtgcgccacc aaccgtgtaa tgcaaatgtc gctgccattt
     6961 tagataccct cttcatgtga actttcgtac tagttaactg gttcaatgga ataatgtcaa
     7021 cacctatttc agtatatttg ccggaaccgt tatgatgtac atgacatacc tttatctcta
     7081 tgggagccgc cttgagcgac acgaattacg cagtgattta cgatctgcac agtcatacca
     7141 cggcgtccga tggactgttg acgccagaaa cattagtaca ccgtgcggta gagatgcgag
     7201 tcggcacgct ggcgattacc gatcatgaca ccacagctgc gattcctgcg gcaagagaag
     7261 aaatttcacg ttgcgggctg gccctgaatc tgattcccgg cgtggagatt tcaacggtct
     7321 gggagaatca tgagattcac attgtgggtc tgaatattga tattgcgcac ccggcaatgc
     7381 gcgattttct agcgcagcag acacatcggc gtcaggcgcg tggtcggctc attgcggagc
     7441 gtctggaaaa agcccatatt cccggcgcgt gggaaggggc attgagactg gccaatggcg
     7501 gcgcggtgac gcgcggccac ttcgcccgct ttctggtgga gtgcggcaaa gccacgacca
     7561 tggcggaggt ttttaaaaaa tatctcgcgc gtgggaaaac cggttacgtt ccgccgcagt
     7621 ggtgtacaat agaacaagct attgatgtca ttcatcattc tggcggtaag gcggtgttgg
     7681 cccacccggg acgctacgac cttagcgcta agtggctgaa aagattagtg gcgcattttg
     7741 ccgaccatca cggcgacgcg atggaagtgg cgcagtgcca acaatcaccc aatgaacgca
     7801 cccaactggc gacgcttgcg cgtcagcatc atttatgggc atcgcttgga tctgatttcc
     7861 atcagccctg cccgtggatt gagttggggc gtaaactctg gctgcccgct ggcgttgaag
     7921 gcgtatggca ggcatgggaa cagccgcaaa tatcacagtg agggaagtat gagccagttt
     7981 ttttatatcc atccggataa cccacagcaa cggctgatta atcaggccgt cgacattgtg
     8041 cgtaaaggcg gtgttattgt ttatccaacc gattccggct atgcccttgg ttgtaaaatt
     8101 gaagacaaag gcgcaatgga gcgcatttgc cgcatccgtc atctgccgga cggccacaac
     8161 ttcacgctga tgtgccgcga tttgtccgag ttgtcgacct actcctacgt cgacaacgtg
     8221 gcatttcgtc tgatgaaaaa caatacgccg ggtaattaca cctttatcct gaaggggaca
     8281 aaagaggtgc cgcgccgtct gttgcaggaa aagcgtaaaa ctatcggcct gcgcgtaccg
     8341 tcaaacccga ttgcgctggc gttattggat acgctgggcg aaccgatgct ctcgacgtcg
     8401 ttgatgctgc ctggcagcga ttttaccgag tcggacccgg aggagattaa agatcggctg
     8461 gagaagcagg tggatctgat catccacggt ggttacctcg gtcaacagcc taccacggta
     8521 atcgatttga ccaatgactc cccggtggtg ctgcgcgaag gcgtcggcga cgttacacct
     8581 ttcttataag ggcgtaagcc tgtatactac gcggccttaa aatggcgcgg caacgcgccg
     8641 ttcattctcc tgttcgacgc ctgtgaaggc gacacctgaa ggaagctcta tgagcgaaaa
     8701 gttacaaaaa gtgctggcgc gcgctggcca cggctctcgc cgtgaaatcg aatccattat
     8761 tgaagcggga cgtgtcagcg ttgacggtaa aatcgccacg cttggcgatc gtgttgaagt
     8821 cactcccggt ttgaaaatcc gtatcgacgg tcacctgatt tcggtgaaag agtcggcgga
     8881 acaaatttgc cgcgttctgg cctattacaa accagaaggt gaactgtgta cccgcaatga
     8941 ccctgaaggg cggccaaccg tttttgatcg cttaccgaaa ctgcgcggcg cgcggtggat
     9001 tgcggtagga cgtctggatg tcaacacctg cgggctattg ttgtttacca ccgacggtga
     9061 actggcgaac cgcctgatgc atcctagtcg cgaagttgaa cgtgaatatg ccgtgcgcgt
     9121 gttcggtcag gtggatgaat cgaaactgcg tgatttaagc cgtggcgtac agttggaaga
     9181 tggtccggcg gcatttaaga ccattaaatt cagcggcggc gaaggcatta accagtggta
     9241 taacgtgacg ctgacggaag ggcgcaaccg cgaagttcgc cgactgtggg aagcggtagg
     9301 cgttcaggtc agccgtctga tccgcgttcg ttacggcgat atcccgctgc cgaaaggcct
     9361 gccgcgcggc ggctggactg agctcgacct cgcgcaaacg aactatctgc gtggtctggt
     9421 agagctcccg ccggaaacct cgtcgaaggt tgccgtcgaa aaagaccgtc gtcgtatgaa
     9481 agcgaaccag atccgtcggg cggtaaaacg ccacagccag atagctggcg gacgccgctc
     9541 cggtgggcgt aataacaacg ggtaatctct accgtggttt ataggccgag agtcatcaga
     9601 caagagggtt tgtgccggat ggcggcgcaa acgccttaat ccggcctacg gttaataatc
     9661 aattcccatc tgggctttta cgcccgcgtc gaaagcatgt ttaaccggac gcagttcgct
     9721 gacggtatcc gcaaaatcaa gaatatcccg gtgacagccg cgacctgtaa taatcaccgt
     9781 ctggtgacca gggcgcgcgt ttagcgcgct tatgacctct tccagcggta aatagtcata
     9841 cgccaccata taggtcagct catccagcac taccatatca agcagcggat cggccagcat
     9901 tcgtttccca tgctgccaaa cggccataca tgctgcggtg tctgcctcgc gattttgcgt
     9961 ctcccaggta aatcccgttg ccatcacctg aaattcgacg ccatgcggtt ccagcagatt
    10021 acgctcgccg ttgggccagg tgcctttaat aaattgcacc acgcctacgt ttttaccgtg
    10081 tcctacggcg cgggcggcag ttccgaaagc cgccgtggtt ttgcccttac cattgccagt
    10141 aaacacgata ataataccgc gctcttcctg tgcctgggcg acacgggcgt caacccgatc
    10201 ttttaccttc tgctggcgct gctgataacg ttcatcactc attgggcgat tcctggttta
    10261 cggcccggtt gggcgtcaaa ggtcataccg gttttacggc gactgtcgtc gcccataagc
    10321 cacaggtaaa gcggcataat atcggcaggc gtttttaatt tctgtggatc ttccgtcgga
    10381 aaggcgctgg cgcgcatact ggtgcgcgtg ccgcccgggt taatgcagtt aacacgcaga
    10441 gaacggttct ggtattcgtc cgccagcacc tgcatcattc cttcagtagc aaacttcgag
    10501 gtggcatagg cgccccagtt ggcgcgtccc tgacggccaa cgcttgatga cgtaaagacc
    10561 agcgagccgg catcggactt caataataac ggtaacagcg cctgggtgag cataaaggtg
    10621 gcgttaacgt ttacctgcat gacatcctgc cagatctgcg gatcttgttc gctcattggg
    10681 ccgatttccc ccagtaaccc ggcattgtgc aggacgccat ccaggcgggg atagtgcgcg
    10741 gcgatgcggt cggccacttg ccggcactct tcagcggtgc aggtcagcag atcgagcgta
    10801 aaccactgtg gttgaacatg ttgctcgtca gcaatgtgct gcgcgacccg acgcagtttc
    10861 tcttcgttgc gtcccagcag aatcaccgtt gcgccgtaac gcgcatacgt gagcgcggct
    10921 tcccgcccaa tgccatcgct ggcaccagtg accagaataa tgcggttttg caatagatct
    10981 tgtttcggtt ggtaatgcat ggctactcct caacggtgtg gtgcaccgtc ctgccaggtt
    11041 gtcttatctt cgcgttaact tttcgggttt atgcctgaaa gcgccttttt tttcaatcag
    11101 acaggggcga taacgccgta aaatgaacgt cttgtcatac tttttcttcc tcaacaggca
    11161 tacggatgaa gagagactga cttcgatgcc tgttgtacac tgagcgcaag tcgcgttatt
    11221 taatcaaggt gggagtcgtg gaattgttgt ctgaatatgg cttatttttg gcaaaaatcg
    11281 tcaccgttgt ggtggccatt gccgtcattg tgctgctgat cgtgaatgct acgcaacgca
    11341 aacgtcagcg cggcgagctg cgcgtgacca atttgagtga gcagtatcag gagatgaagg
    11401 atgaccttgc tgcggcgttg atggatggcc atcagcaaaa actgtggcat aaagcgcaga
    11461 aaaaaaagca taagcaggag gcgaaagccg ccaaagcgaa agcgaagctg ggggacattg
    11521 cgacatcgga caaaccgcgc gtatgggtga tagatttcaa aggcagtatg gacgctcacg
    11581 aagttaatgc gttacgcgaa gaggtcacgg cggtgctggc agtggcgaaa cccggcgatc
    11641 gggcggttgt gcgtctggaa agccccggtg gcgttgtgca cggctatggc ctggcggcat
    11701 cgcaattgca gcgcctgcgc gataaaaata ttccgctgac cgtgacggtg gataaagtcg
    11761 cggcaagcgg aggctacatg atggcctgcg tggcggaaaa aattatcgcg gcgccgttcg
    11821 ctattgtggg gtcaattggt gttgtcgcgc aaatcccgaa ctttaaccgc tttctcaaaa
    11881 gtaaagacat tgatattgaa ctgcataccg cagggcagta caaacgtacc ctgactttgt
    11941 taggcgagaa tacggaagaa gggcggcaga agtttcgtga agatctcaac gaaacgcacc
    12001 atctgttcaa agagtttgtg cagcggatgc gtccggctct ggacattgaa caggtcgcca
    12061 cgggcgaaca ctggtacggt cagcaggcgc tggagaaggg actggttgat gagattaaca
    12121 ccagcgatga ggttatcctc ggcctgatgg aagggcgcga ggtgctgaat gtgcgctata
    12181 tgcagcgtaa aaaactgatc gatcgtgtta ccggcagcgc ggcggaaagc gcggatcggc
    12241 tgctgctgcg ctggtggcag cgtggacaaa agccgttgat gtaaaccgct attgccggat
    12301 ggcattcagc gccatccggc atggattaat caaccaggtg atacttctca gacagcacat
    12361 gcgccaggtg tttaaacatg ttaaacaccg cggtgctttt aggggtcggt aacccttgct
    12421 cgtctaaaaa gtaatcgccg ctgaaaacca gcacgccatt tctctgcgtt acgccggtgg
    12481 cgacaatacc tgccatcgtg tcttcatgtt cccgaataat tttgttggct tcaagcaaca
    12541 gtgtttcgcg atcgataggt tgcgtctctt tatgcatttt ttactcctta aacaaggaga
    12601 ttagtctacg ctgagcactt ctgatgggca aatattctca caggaaattg atggatttgt
    12661 catgttgcgt tcactggcaa gatttgtttt tgcatgctaa taaagttgcg tatcgaattt
    12721 tatcaggtac agtgtgacgc tttcgtcaat ctggcaacag aattgcttga cattcgacca
    12781 aaattccgtc gtgctatagc gcgtgtgtgc aaaaaagcct gttaactcag tcacctgagg
    12841 gttacatttc gtacacaaag ccagtacaag gggttgatat ccgcagacgc agagaccata
    12901 tatcgttgtc tcgtcgccag tggaaggtga atcaacgtgc gacgcattcc tggaagaatc
    12961 aacttaggta aaggtgaata tgggtaaagc tcttgtcatc gttgagtccc cggcaaaagc
    13021 caaaacgatc aacaagtatc tgggtaatga ctacgtggtg aaatccagcg tgggtcatat
    13081 ccgtgatttg ccgaccagtg gctcagcagc taaaaagagc gccgactcta cctccaccaa
    13141 aacggctaaa aagcccaaaa aggatgaacg tggcgctctc gtcaaccgta tgggggttga
    13201 cccgtggcac aactgggatg cgcactatga agtgctgccc ggtaaagaga aggtcgtctc
    13261 tgaactgaaa cagttggcgg aaaaagccga ccacatctat ctcgcaaccg accttgaccg
    13321 cgaaggggaa gccattgcat ggcacctgcg ggaagtgatc ggcggcgatg acgcgcgcta
    13381 cagtcgcgta gtctttaacg aaataaccaa aaatgccatt cgccaggcgt ttgaacagcc
    13441 gggcgagctg aacattaaca gggtcaacgc ccagcaagcg cgccgcttta tggaccgcgt
    13501 ggtaggctat atggtctcgc cgctgctgtg gaaaaagatc gcccgtggtt tgtcggcagg
    13561 tcgcgttcag tctgtcgcgg tccgtctggt cgttgagcgc gagcgcgaga ttaaagcgtt
    13621 tgttccggaa gagttctggg agattgacgc taatacgacg acgccgtctg gcgaggcact
    13681 accgctacag gtcacgcatc agaacgacaa gccattccgg ccggtaaatc gcgagcagac
    13741 gcttgccgcc gtcagcttgt tggaaaaagc gcgctatagc gtactggagc gtgaagacaa
    13801 accgaccagc agcaaacctg gcgcgccgtt tatcacctcc acgctacaac aggcggccag
    13861 cacccggctg ggctttggcg tgaagaaaac catgatgatg gcgcagcgtc tgtatgaggc
    13921 gggctacatc acctatatgc gtaccgactc caccaacctg agtcaggatg cggtcaacat
    13981 ggtgcgcggc tatattggcg ataatttcgg caagaaatac ctgccggata acccgaacca
    14041 atacgccagc aaagaaaact ctcaggaagc gcacgaagcg atccgtcctt ccgacgttgc
    14101 tgtcatggcg gagtcgctga aagacatgga ggctgacgcg cagaagttgt atcagctaat
    14161 ttggcgtcag tttgtcgcct gtcagatgac gccagcacaa tatgactcca ctacgcttac
    14221 cgttggcgca ggcgaattcc gtctgaaagc gcgtgggcgt attttgcgct ttgacggctg
    14281 gacaaaagtg atgccggcgc tgcgtaaagg cgatgaagat cgcacattgc ctgccgtgaa
    14341 taagggcgat gcgctgacgc tacttgaatt gacgcctgct cagcacttta ctaaaccgcc
    14401 agcccgtttc agcgaggctt ctctggttaa agagcttgag aagcgcggta ttggtcgtcc
    14461 gtctacctat gcgtcgatta tctcgaccat tcaggatcgc ggctatgttc gcgttgaaaa
    14521 ccgtcgcttc tatgcggaaa aaatgggtga aatcgtcacc gaccggctgg aagaaaactt
    14581 ccgcgaattg atgaactacg attttaccgc gcagatggaa gatagtctgg atcaggttgc
    14641 gaatcaccag gccgagtgga aagcggtgct ggataacttc ttcagcgatt ttactcagca
    14701 gctcgataaa gccgagaaag atccggaaga aggggggatg cgtcctaacc agatggtgct
    14761 gaccagcatc gactgtccaa cctgtggccg taaaatggga attcgtactg ccagtacggg
    14821 ggttttcctt ggttgttcag gttatgcgct ttcgccgaaa gagcgttgta aaacgaccat
    14881 taacctggtg ccggaaaatg aagttctgaa cgtgctggaa ggcgacgacg ccgaaaccaa
    14941 cgccctgcgc gccaaacgtc gctgtcagaa gtgcggtacg gcgatggaca gctatctgat
    15001 cgatccgaag cgtaaattgc atgtgtgtgg taataacccg acctgtgacg gctacgagat
    15061 tgaagaaggc gagttccgca tcaaagggta tgacggcccg atcgttgagt gtgagaaatg
    15121 tggttccgaa atgcacctga aaatggggcg ttttggtaag tacatggcct gtactaacga
    15181 cgaatgtaaa aatacccgta agatcttgcg taacggcgaa gttgcgccgc cgaaggaaga
    15241 tcctgttcca ttgccggaac tgccgtgtga aaaatcggac gcgtactttg tgctgcgcga
    15301 tggcgccgca gggatattcc tggcggccaa tacgttcccg aaatcacgtg aaacgcgcgc
    15361 gccattagtc gaggagcttt accggttccg cgatcgcctg ccggaaaaac tgcgttatct
    15421 ggcggatgcg ccgcagcagg atccagaagg caataaaacc gttgttcgct ttagccgcaa
    15481 aacaaaacag cagtacgttg cggcggaaaa agacgggaag gcgacgggat ggtcagcgtt
    15541 cttcgtcgac ggcaagtggg ttgaaggtaa gaaataaccc cggcctgtcg ccactgtagt
    15601 caagcgggcc gcgtaagcgg ccctttttta tatccccttc atatttcaag tggcttatgt
    15661 gttggctacg gattactcgg cccatctatg ggcctcgccc tgacgggccg tcgcacgcga
    15721 cgttcaaatc tgctcccggc tgatttgtcg ctcaccccag tcccctg
//
LOCUS       DAJVKX010000104        15581 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000104 DAJVKX010000000
VERSION     DAJVKX010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15581
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.104"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            115..1716
                     /gene="aceB"
                     /locus_tag="OPY25_003291"
     CDS             115..1716
                     /gene="aceB"
                     /locus_tag="OPY25_003291"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HCS0928827.1"
                     /translation="MNPQATTTDELTFTRPQGELEKQVLTAEAVEFLTELVTRFTPKR
                     NKLLAARIQQQQDIDNGKLPDFISETTSIRESNWQIRGIPADLQDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPDP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYKALLAKGSGPYFYLPKTQA
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNHPDRVLPDRQVVTMDKPFLSAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDVERNNQVLAKVKADKALEANNGHDGTWIAHPGLADTAMAVFNEVLGEHKNQLFI
                     TRDEDAPITAEQLLEPCEGERTEAGMRANIRVAVQYIEAWIPGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHEKTLSNGKPVTKALFREMLAEEMRVIQDELGEHRYSSGRFDDAA
                     RLMEQITTSDDLIDFLTLPGYRLLA"
     gene            1748..3052
                     /gene="aceA"
                     /locus_tag="OPY25_003292"
     CDS             1748..3052
                     /gene="aceA"
                     /locus_tag="OPY25_003292"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HCS0928828.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEEVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGEAKKGYINSLGALTGGQALQQAKAGIEAIYLSGWQVVADANLA
                     SSMYPDQSLYPANSVPAVVDRINNTFRRADQIQWASGIEPNDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKSMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVMGVPTLVIARTDADAADLITSDCDPYDSGFITGERTSEGFYRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFADAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKYQFITLAGIHSMWFNMFDLAHAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGASSVTALTGSTEESQF"
     gene            3153..4934
                     /gene="aceK"
                     /locus_tag="OPY25_003293"
     CDS             3153..4934
                     /gene="aceK"
                     /locus_tag="OPY25_003293"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HCS0928829.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWEPLLMRILSDL
                     PLCLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDG
                     TLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRV
                     FKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMAL
                     LRQEAPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRR
                     QRFSVRYETDRRPDKAFAPPSGNVRRA"
     gene            complement(4979..5803)
                     /gene="iclR"
                     /locus_tag="OPY25_003294"
     CDS             complement(4979..5803)
                     /gene="iclR"
                     /locus_tag="OPY25_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HCS0928830.1"
                     /translation="MVAPVPAKRGRKPAATTAPVTGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAVGAHAFIVGSSFLQSRNLL
                     AIVHPILRKLMEDSGETVNLAVLDQSDHQAIIIDQVQCTQLMRMSAPIGGKLPMHASG
                     AGKAFLSQLSEEQVTSLLHRKGLHAYTHATLVSPLHLKDDLAQTRKRGYSFDDEEHAL
                     GLRCVASCIYDEHREPFAALSISGPCSRITDDRVTELGAMVIKAAKEVTLAYGGFR"
     gene            6107..9790
                     /gene="metH"
                     /locus_tag="OPY25_003295"
     CDS             6107..9790
                     /gene="metH"
                     /locus_tag="OPY25_003295"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCS0928831.1"
                     /translation="MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAE
                     INYAAAKLARACADEWTARTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLSPRQLP
                     DIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     SGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQG
                     KGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKIL
                     LEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDNLPAELRDAVEDVILNRR
                     DDGTERLLDLAEKYRGSKTDEAASAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEA
                     RQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDL
                     AFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLR
                     QQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLKEDALADAFEAQHDDYNKIMV
                     KAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHT
                     EKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYA
                     FRKGMSVEDVERWLAPNLGYDAD"
     gene            10047..11678
                     /locus_tag="OPY25_003296"
     CDS             10047..11678
                     /locus_tag="OPY25_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HCS0928832.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTLLVTSFVAQDLVALTPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDIMLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLIGSLVILPFVHPLANLMDELPLPKSELVI
                     YFHVFYNLVRCLAMVPFAELMARFCKRIIRDEPELDTHLKPKHLDVSALDTPTLALAN
                     AAREVLRIGDAMEQMMEGLKKVMHGEPREEKALRKLADDVNVLYTAIKLYLARMPKDE
                     LAAEESRRWAEIIEMALNLEQASDIIERMGSEIADKSLAARRAFSEEGLKELDALYDQ
                     LLSNLQLAMSVFFSGDVTSARRLRRSKHRFRILNRRCSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMKRLNSLFCSVAYSVLEQPDQDEERGEY"
     gene            complement(11768..12457)
                     /gene="pepE"
                     /locus_tag="OPY25_003297"
     CDS             complement(11768..12457)
                     /gene="pepE"
                     /locus_tag="OPY25_003297"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HCS0928833.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQ
                     TWDEYTDKTAEVLAPLGINVTGIHRVADPLAAIEKAEIVIVGGGNTFQLLKESRERGL
                     LAPVADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTN
                     ALPEGHKGETREQHIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGE
                     EAVALEAGHRF"
     gene            12529..12630
                     /locus_tag="OPY25_003298"
     CDS             12529..12630
                     /locus_tag="OPY25_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928834.1"
                     /translation="MAHDVARVTGNARSLKVTPGQICHLVSPEKLQV"
     gene            12665..13204
                     /locus_tag="OPY25_003299"
     CDS             12665..13204
                     /locus_tag="OPY25_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HCS0928835.1"
                     /translation="MAKLTLQEQLLQAGLVTSKKMAKVQRTAKKSRVQAREAREAVEE
                     NKKAQLERDKQLSEQQKQAVLAKEFKAQVKQLIEMNRINVSKGDIGFNFTDNNVIKKI
                     DVDKLTQTQLINGRLAIARLVINNSGECEYAIIPASVADKIAQRDADSIVVNSALSQE
                     EQDEDDPYADFKVPDDLMW"
     gene            13251..14120
                     /gene="rluF"
                     /locus_tag="OPY25_003300"
     CDS             13251..14120
                     /gene="rluF"
                     /locus_tag="OPY25_003300"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HCS0928836.1"
                     /translation="MLTDTSTRLNKYISESGICSRREADRFIEQGNVFINGKRAAIGD
                     QVVAGDVVKVNGRLIEPREADDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRIFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEYFGYEVTKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIEGSSSEAKPKAKAKPKTAGIKRPVVAIEKSNEKARPASSG
                     KRFTSPGRKKKGR"
     gene            complement(14117..14389)
                     /locus_tag="OPY25_003301"
     CDS             complement(14117..14389)
                     /locus_tag="OPY25_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HCS0928837.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRPLTNSETNSVKK
                     EYIDKLMALREAEAKKARQLKKKQAYKPDTEASFSWSANTPTRGRR"
     gene            complement(14452..15210)
                     /locus_tag="OPY25_003302"
     CDS             complement(14452..15210)
                     /locus_tag="OPY25_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0928838.1"
                     /translation="MNPIKRRKHILDELNKFGEVTVIKLSEMLNVTSETIRRDLSLLE
                     SEGKITKIHGGAVKKQVVQEDAFSARIEAHREEKIAIGKLAAEMISERDTLFIDSCTT
                     NLILAEQLPPLAFSVITNSALIADKIKEHNLQARVYVLGGEYDYHFRANLGVSVCQQI
                     NAIHADICFIGAGGISPQHGVLVKSFEEAYVAKAMIAMSKKSVILADHTKFGQDGVMC
                     IASVKEIDNIITDKGFTSTGYTPQDFAGKLRIAD"
     gene            complement(15197..>15581)
                     /locus_tag="OPY25_003303"
     CDS             complement(15197..>15581)
                     /locus_tag="OPY25_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HCS0928839.1"
                     /translation="IDTLCTEVNNHLPYGYYAVVTGENYIDIQRTDVNKGCIIEQLIH
                     YLNISSDKVVVIGDQQNDVSMFAAAGISIAMGNAPDAVKRQADYVTATNDEEGIVHAL
                     EWLRCLTHPVTMRQRLTAAKDNESN"
BASE COUNT         3625 a         4010 c         4360 g         3586 t
ORIGIN      
        1 tgtttttgat tttgaaattt aattgagtag tcttagttgt gttgaacgaa aagcgcacag
       61 tgatccttcg ttcgcattgg ggatgtatct ggatcaacaa cgaggagctg catgatgaat
      121 ccacaggcaa ccacaactga tgaattaacc tttaccaggc cgcaaggcga gctggaaaag
      181 caagtcctga ccgctgaggc agtcgagttt ttgacggagt tagtcacccg ttttacgcca
      241 aaacgcaata aactcctggc tgcacgtatc cagcaacagc aggatattga taacggtaag
      301 ttgcctgatt ttatttcgga aaccacttcc attagagaaa gtaattggca gattcgtggt
      361 attccggcgg atttacagga tcgccgagta gaaattaccg ggccggttga acgtaaaatg
      421 gtgattaatg ccctgaacgc aaatgtgaaa gtgtttatgg cggattttga agactcgctg
      481 gcgccggact ggaataaagt tattgatggt caaatcaacc tgcgtgatgc ggtgaacggc
      541 accattagct ataccaacga agccggaaaa atctatcagc tcaagcccga tccggccgta
      601 ttgatttgtc gtgtacgcgg tctacatctg ccagaaaaac atgttacctg gcggggggaa
      661 gccattcccg gcagcctgtt tgattttgct ctgtactttt tccacaacta caaagcgctg
      721 ctcgctaaag gtagcggccc gtatttttac ctgccgaaaa cgcaagcctg gcaggaggca
      781 gcctggtgga gtgaagtttt cagctacgcc gaagaccgct tcaatctacc gcgcggtacg
      841 atcaaagcga ccctgttgat tgaaacgctg cctgctgttt tccagatgga tgagattctt
      901 catgcgttgc gtgatcatat cgtcggtctc aactgtggtc gctgggatta tattttcagc
      961 tatatcaaaa cgttgaaaaa tcacccggat cgcgtcctgc cggacaggca ggtggtaacg
     1021 atggacaaac cgtttctgag tgcctactcg cgcctgctga tcaaaacctg tcacaagcgc
     1081 ggcgcgttcg cgatgggcgg tatggcggcg tttatcccga gcaaagacgt tgaacgcaat
     1141 aatcaggtcc ttgccaaagt gaaagcggat aaagcgctgg aagcgaacaa cggccacgac
     1201 ggcacgtgga ttgcgcatcc cgggttggcg gatacggcaa tggccgtctt taacgaggta
     1261 ctgggcgagc acaaaaatca gctgttcatt acccgtgatg aagatgcgcc gattaccgct
     1321 gagcagttac tggagccatg tgaaggcgaa cgcacagaag cgggaatgcg cgccaatatt
     1381 cgcgtggcag tgcagtacat tgaagcgtgg atccccggca atggctgtgt accgatttac
     1441 ggtctgatgg aggatgccgc gacggcggaa atctcacgaa cctctatctg gcagtggatt
     1501 caccatgaga aaacactgag caatggaaaa cccgtaacga aagcgctttt ccgcgaaatg
     1561 ttggcggaag agatgcgggt aatccaggac gaactgggcg agcaccgcta cagcagcggg
     1621 cgcttcgacg atgccgcacg tctgatggag caaatcacca catcagatga cttaatcgac
     1681 ttcctcaccc tgccgggcta tcgcttactg gcttaattca ccacataaca atatggagca
     1741 tctgcacatg aaaacccgta ctcaacaaat cgaagaatta cagaaagagt ggacacaacc
     1801 gcgctgggaa ggcatcaccc gcccgtacag cgcggaggag gtggtgaaat tacgcggctc
     1861 ggttaacccg gaatgcacgc tggcgcagct cggcgccgcg aaaatgtggc ggctgttgca
     1921 cggtgaagcg aaaaaaggct atatcaacag cctgggcgcg ctgactggcg gtcaggcgct
     1981 gcagcaggcg aaagccggta ttgaggcgat ttatctttca ggctggcagg tggtggcaga
     2041 tgccaacctg gcatccagca tgtatccgga tcaatcgttg tacccggcaa actctgttcc
     2101 ggcggtagtg gatcggatca acaacacttt ccgtcgtgca gatcagatcc agtgggcatc
     2161 cggtattgaa cccaacgatc cgcgctatgt ggattacttc ctgccgatcg ttgctgatgc
     2221 ggaagccggt tttggcggcg ttctgaatgc cttcgaactg atgaaatcga tgattgaagc
     2281 cggtgcagcg gccgttcact tcgaagatca gctggcgtcg gtgaagaaat gcggccatat
     2341 gggcggcaag gtgctggtcc ccacgcagga ggcgattcag aaactggttg ctgcgcgtct
     2401 ggccgctgat gtgatgggcg tcccgacgct ggtgattgcg cgtaccgatg cggatgcggc
     2461 agatctgatc acctccgact gcgatcccta tgacagcggt tttattaccg gcgaacgcac
     2521 cagcgaaggt ttttaccgca cccatgcggg cattgagcag gcgatcagcc gcggtctggc
     2581 gtatgccccg tatgccgatc tggtatggtg cgaaacttct acgccggatc tcgaactggc
     2641 gcgtcgtttt gccgatgcta tccacgcgaa gtatccgggc aaactgctgg cctataactg
     2701 ttcgccatcc ttcaactggc agaagaatct ggacgacaag accattgcca gcttccagca
     2761 gcagttgtcg gacatgggtt acaaatacca gtttattacc ctggcgggca tccacagcat
     2821 gtggttcaac atgttcgacc tggcgcatgc atacgctcag ggtgagggca tgaaacacta
     2881 tgttgagaag gttcaacaac ccgagttcgc cgcagcgaaa gacggttaca cctttgtttc
     2941 ccaccagcag gaagtgggta ctggttactt cgacaaagtc accaccatta ttcagggcgg
     3001 cgcgtcatcc gttaccgcgt taacgggttc caccgaagaa tcgcagtttt gattgatgcc
     3061 cggtggcgct gcgcttaccg ggcctacaga tagcgtaggc cggataagcg aacgcgccat
     3121 ccggcatgat gtggtgccgg atgagggaaa aaatgccgcg tggcctggaa ttactgattg
     3181 ctcaaaccat cctgcaaggc tttgacgcgc agtatggtcg atttctggaa gtgacttccg
     3241 gcgcgcagca gcgttttgaa caggccgact ggcacgccgt ccagcaggcg atgaaaagcc
     3301 gtatccacct ctatgatcat catgtgggtc tggtggtgga gcaactgcgc tgtattaccg
     3361 atggcaaaag taccgacgcg gatttccttt tacgcgttaa agagcattac acccggctgt
     3421 tgccggatta cccgcgcttc gagattgcgg agagcttttt caactccgtt tattgccggt
     3481 tatttgacca ccgctcgtta acacccgagc ggttgtttat tttcagttcg caaccggagc
     3541 gtcgcttccg tactatcccg cgcccgctgg ccaaagactt ctttcccgat cacggttggg
     3601 agccgctgtt gatgcgcata ctcagtgact taccgctgtg tctaccctgg cagaataaaa
     3661 gccgggatat ccgctatatt atcgcgcacc tgactgaaac actgggcgag gacgcgctac
     3721 ctcgctgcca tgtccaggtg gcgaacgagt tgttttaccg taataaagcg gcctggctgg
     3781 taggtaaatt aaccacacct gacggtacgc tgccgttttt attgccgatt catcgcactg
     3841 atgaggggga actgtttgtc gatacctgcc tgaccaccac ggcagaagcg agcattgtgt
     3901 ttggttttgc ccgctcttat tttatggtgt atgcgccgct gcctgccgcg ctggttgagt
     3961 ggttgcgtga aatcctgccg ggtaaaacca ctgccgaact gtatatggcg attggctgcc
     4021 agaaacatgc gaaaaccgaa agctaccgcg aatatttatg ttatctggct gaaagcgatg
     4081 agaaattcat tgaggcgcct ggaatccgcg gcatggtgat gctggtattt accctgccag
     4141 gcttcgaccg ggtatttaaa atcattaaag acaaattcgc cccgcagaaa gagatgtctg
     4201 ccgcccatgt gcgtgcctgt tatcaactgg taaaagagca tgatcgcgtc ggtcgtatgg
     4261 cggataccca ggagtttgag aatttcgtac tggataaacg gcaaatcgat ccggcgctga
     4321 tggcgctgtt acgacaagaa gcgccagaga agattaccga tcttggggaa catatcgtca
     4381 ttcgccatct ctatattgaa cgtcgcatgg tgccgctcaa tatctggctg gaacaggtag
     4441 aaggccagca gttgcgcgat gcgatagaag aatatggtaa tgcgattcgc cagcttgccg
     4501 ccgctaatat tttccccggc gatatgttgt ttaaaaactt tggcgttacc cgtcatggtc
     4561 gcgtggtgtt ctacgactac gatgaaattt gctacatgac ggaagtgaat ttccgcgata
     4621 ttccgccagc gcgttatccg gaagacgaac tggccagcga accctggtat agcgtctcgc
     4681 cgggtgatgt tttcccggag gagtttcgcc actggctgtg tgccgatccg cgtatcgggc
     4741 cattgtttga agagatgcat gccgacctgt ttcgcgccga ttactggcgc gcgctacaga
     4801 cgcgtattaa agaagggcat gtagaagatg tgtatgccta tcgtcgccgc cagcgcttta
     4861 gcgtgcgtta tgaaaccgac cgtaggccgg ataaggcctt tgcgccgcca tccggcaatg
     4921 tacgccgtgc ctgatggcgc tgcgcttatc aggcctacaa atcagttcca acccttgctt
     4981 atctaaaccc accataggcc agcgtcacct ctttcgccgc tttaatcacc atggcgccaa
     5041 gttcggtgac gcgatcgtcg gtaatgcgtg agcaggggcc ggaaatagag agggccgcaa
     5101 acggttcgcg gtgttcgtca taaatacacg aggccacgca gcgcagaccg agcgcatgtt
     5161 cttcgtcgtc aaaggaatag ccgcgcttgc gtgtttgggc gaggtcatct ttcagatgca
     5221 gcggcgacac cagcgtcgca tgggtataag cgtgcaaccc cttgcggtgc agcagactgg
     5281 taacctgttc ctcactgagc tgtgataaaa acgccttgcc cgcgccagag gcgtgcatgg
     5341 gcagcttgcc gccaataggg gcggacatgc gcatcaattg tgtgcactgc acctggtcga
     5401 taataatagc ctgatggtcg ctctggtcga gtacggcaag gtttaccgtt tcgccggagt
     5461 cctccatcag cttgcgcaaa atcggatgga caatcgccag cagattacgg ctctgtaaga
     5521 agctgctacc gacgataaac gcgtgtgcgc ctacggccca gtggcccagc tcaccaacct
     5581 ggcggacaaa accctgttgc tgcatggtgg tgagtagacg gtgagtcgtg gaattaggca
     5641 aacccgcctg ttgcgccagt tcggtcagcg cgacgctgcc gttggactcg gcaatccact
     5701 ccagcagctt cagaccgcga gttaaagact gaacctgccc ggttacgggt gcagtggtag
     5761 cggcaggttt tctcccgcgt tttgcgggaa caggggcaac catggcagac tcctttttct
     5821 gtatcgtgga aatcattttc gttttattca attataatgc aagagttcct gaactgatcg
     5881 gatgagtgac atcacaggat gcccgatggc gctgcgctta tcaggcctac gctttgggag
     5941 ccgccaaagt aatttgtaga ctgataaggc gcttgcgccg ccatccggca aagcgacaga
     6001 agtgggtggc aagctgaaca tgtctcatgt tgcccgttgt tctcttttcc gccagcacgc
     6061 tttgtgccag tatggctcgt tacgtggagc gttgtcggga gcgagtgtga gcagcaaagt
     6121 tgaacaactg cgtgcgcagt taaatgaacg tattctggtg ctggacggcg gtatgggcac
     6181 catgatccag agctatcgtc tacatgaaga agatttccgc ggggagcgct ttgccgactg
     6241 gccctgcgac ctgaaaggca acaatgacct gctggtcctc agcaagccgg aggtgatcgc
     6301 cgctatccac aacgcctact ttgaggctgg cgcggatatc atcgaaacca acacctttaa
     6361 ctcgacaacc attgcgatgg cggattaccg gatggaatcc ctgtcggcgg aaattaacta
     6421 tgcggcggcc aaactggcgc gcgcctgcgc cgatgaatgg acggcgcgaa caccagaaaa
     6481 accacgcttt gttgcgggcg tgcttggtcc aactaaccgc acggcctcca tttcgccgga
     6541 cgtcaacgac ccggcgtttc gtaatatcac cttcgatcag ctggtggcgg cctaccgtga
     6601 atccaccaaa gcgctggtgg aaggcggggc ggacctgatc ctgattgaaa ctgtcttcga
     6661 caccctcaac gccaaagcgg cggtgtttgc ggtgaaagaa gagtttgaag cgctgggcgt
     6721 tgatctgccg atcatgattt ccggcaccat caccgacgcc tctggccgta cgctttccgg
     6781 ccagacgacc gaagcctttt ataactcgct gcgccacgcc gaggcgctca cttttggcct
     6841 taactgcgcg ctggggccag atgaactgcg ccagtacgtc caggaactgt cgcggattgc
     6901 cgaatgctac gtcaccgcgc acccgaacgc cggcctgccg aacgctttcg gcgagtacga
     6961 cctcgacgcc gacaccatgg cgaaacagat tcgcgaatgg gcggaagcgg gcttcctgaa
     7021 tatcgttggc ggctgctgcg gcaccacgcc ggagcatatt gcggcgatga gccgcgccgt
     7081 tgccggtttg tcgccgcgcc agctgccgga tatcccggtg gcctgccgcc tttccggcct
     7141 ggagccgctg aacattggtg acgatagcct gtttgtcaac gtcggcgaac gtactaacgt
     7201 caccggctcg gccaaattta aacgcttgat caaagaagag aaatacagcg aagcgctgga
     7261 tgtcgcccgt cagcaggtcg aaagcggcgc gcagattatt gatatcaata tggatgaggg
     7321 gatgctcgac gccgaagcgg cgatggtgcg tttcctcagc ctgattgccg gtgagccgga
     7381 cattgcccgt gtaccaatca tgattgactc ctccaaatgg gaggttatcg aaaaagggct
     7441 gaagtgcatt cagggtaaag gcatcgtcaa ctctatttcg atgaaagagg gcgtggaagc
     7501 ctttattcat catgcgaagt tgctacgtcg ctacggcgcc gcagtggtgg tgatggcttt
     7561 tgatgagcag gggcaggccg acacccgcga acgtaaaatc gagatttgcc gccgcgctta
     7621 caaaattttg ctcgaagagg taggctttcc gccggaagac atcatcttcg acccgaatat
     7681 cttcgccgtc gccaccggta ttgaagagca caacaactac gcgcaggact ttatcggcgc
     7741 ttgtgaagac atcaaacgcg agctgccgca cgcgctgatc tccggcggcg tgtctaacgt
     7801 gtccttctcg tttcgcggca acgacccggt acgtgaggct atccacgcgg tattcctcta
     7861 ctacgccatc cgcaacggca tggacatggg catcgtcaac gccgggcaac tggcgattta
     7921 tgacaacctg cctgccgaac tgcgcgatgc agttgaagat gtcattctta accgtcgcga
     7981 tgacggcacc gagcgtttgc tggatttggc ggagaaatat cgcggcagca aaaccgacga
     8041 ggctgccagt gcccagcagg cggaatggcg tagctgggac gtgaaaaagc gtctcgaata
     8101 ctcgctggtg aaaggcatta ccgagtttat cgaacaggat accgaagaag cccgtcagca
     8161 ggccgcccgc ccgattgagg tgattgaagg gccgctgatg gacggcatga acgtggtcgg
     8221 cgacctgttc ggcgaaggga aaatgttcct gccgcaggtg gtgaaatccg ctcgcgtgat
     8281 gaaacaagcg gtggcctacc tggagccgtt tattgaagcc agcaaagaaa aaggctccag
     8341 caacggcaag atggtgattg ccaccgtgaa gggcgatgtg cacgacattg gcaagaacat
     8401 tgtcggcgtg gtgctgcaat gcaacaacta cgaaatcgtc gatcttggcg tgatggtgcc
     8461 agcggagaaa atcctcagaa cggcgcgtga agtgaatgcc gatctgattg gtctttccgg
     8521 gcttatcacc ccgtcgctgg acgaaatggt caacgtggcg aaagagatgg agcgtcaggg
     8581 ctttactatc ccgctactga tcggcggcgc aaccacttcg aaagcgcata cggcggtgaa
     8641 aatcgagcag aactacagcg gtccgacggt ctacgtgcag aatgcttcgc gtaccgtggg
     8701 cgtggtggcg gcgctactct ccgacaccca gcgtgatgac tttgtcgccc gtacccgcaa
     8761 agagtacgaa accgtgcgta ttcagcacgc ccgcaaaaaa ccgcgcacgc cgccggtcac
     8821 gctggaagcg gcgcgcgata atgatctggc atttgattgg gaacgctaca ccccgccggt
     8881 agcccaccgt ctgggcgtgc aggaggtgga agccagcatc gaaacgctgc gcaactacat
     8941 cgactggacg ccgttcttta tgacctggtc gctggccggc aaatacccgc gcattctgga
     9001 agatgaggtg gtgggcgttg aggcgcagcg tctgtttaaa gacgccaatg atatgctgga
     9061 taaactgagc gccgagaaac tgttgaatcc gcgtggcgtg gtgggcctgt tcccggcgaa
     9121 ccgtgtgggt gacgacatcg aaatctatcg cgacgaaacc cgtactcatg ttctgacggt
     9181 cagccaccac ctgcgccagc agaccgagaa agttggtttt gctaactact gtctggcgga
     9241 ttttgtcgcg ccgaaactga gcggcaaagc ggactacatc ggtgctttcg cggtgaccgg
     9301 cggtctgaag gaggatgcgc tggcggacgc cttcgaagcg caacacgacg actataacaa
     9361 gatcatggtg aaagcgattg ccgaccgtct ggcggaagcg tttgccgagt atctgcatga
     9421 gcgtgtacgt aaggtttact ggggatatgc gccgaacgag agcctgagta acgacgaatt
     9481 aatccgcgaa aactaccagg ggattcgccc ggcgccgggt tatcctgcct gcccggaaca
     9541 taccgaaaaa ggcactatct ggcagctact ggatgtcgaa aaacacaccg ggatgaagct
     9601 caccgaatct ttcgccatgt ggcctggcgc gtcggtctcc ggctggtact tcagccatcc
     9661 tgagagcaaa tacttcgcgg tagcgcagat ccaacgcgat caggtgacag attatgcttt
     9721 ccgtaaagga atgagcgttg aggacgttga gcggtggctc gcgccgaacc tgggttacga
     9781 tgcggactga ttcataaaat cgtcactttt ccttacaaca tacaaggcac tcattgggtg
     9841 ccttgtctct ttcttacaat taaaccctta tactgaagga aggctctacg ctgaatttgc
     9901 cggatggcgg cgtaaacgcc ttatccagca tgtatggtaa gcctggtggc gtgcaacgcc
     9961 accaggcctt aacgctgtgc gccatcaggc aatttatcgc aagtgagctt caggaaaacg
    10021 tataacgata aggagaacct gacgccgtgt taactttgct ccatctactt tctgccgttg
    10081 cgctgttggt atggggaaca catatcgttc gtactggcgt aatgcgcgtg tttggcgcgc
    10141 gtctacgcac tgtcctcagc cgcagcgtgg aaaagaaacc gctcgccttt tgtgcgggta
    10201 tcggtgttac cgcgctggta caaagcagta acgccaccac tttattggta acgtcgtttg
    10261 tcgcccagga tcttgtcgcc ctgacgccag ctctggtgat tgtgctgggc gccgatgtgg
    10321 gtactgcgct aatggcgcgt attctcacct ttgatttgtc gtggctatcg ccgctgctga
    10381 tttttattgg cgtgattttc tttttgggac gtaagcagtc ccgcgccggg cagctgggtc
    10441 gcgtcggtat cgggcttggc ctgattctac tggcgctgga gctgattgtg caggcagtga
    10501 cgccgatcac tcaagctaat ggcgtgcagg tcattttcgc gtcgctgacg ggcgacatta
    10561 tgctggatgc gctgattggc gcgatgttcg ctattatcag ttattccagc ctggcggcgg
    10621 tgttgctgac ggcgaccctg acggcggcgg ggattatatc gttcccggtg gcgttgtgcc
    10681 tggtcatcgg cgccaatctg ggatcgggcc tgttggcgat gctcaacaac agcgccgcca
    10741 atgctgccgc gcgtcgcgta gcgctcggca gcctattgtt caaattgatc ggcagcctgg
    10801 tcatcctgcc gtttgtccat ccgctggcga atttgatgga tgagctaccg ctaccgaaat
    10861 cagagctggt gatctatttc cacgttttct ataacctggt gcgctgcctg gcgatggtgc
    10921 catttgccga gctgatggcg cgtttttgta aacgaattat tcgtgatgag cctgaactgg
    10981 atacccatct gaagccgaaa catctggatg tcagcgcgct ggatacgcca acgctggcgc
    11041 tggctaatgc tgcccgtgag gtgttgcgca ttggcgatgc gatggaacag atgatggaag
    11101 ggctaaaaaa ggtcatgcac ggcgaaccgc gtgaagagaa agcgctgcgc aagctggcgg
    11161 atgacgttaa cgtgctctac accgcgatta agctttatct ggcgcgaatg ccgaaagacg
    11221 agctggcggc ggaggagtcc cgccggtggg cggagattat tgagatggcc ctgaacctcg
    11281 aacaggcgtc ggatattatc gagcgaatgg gcagtgagat tgccgacaag tcgctggcgg
    11341 cgcgtcgggc attttcagaa gaaggattga aagagctgga tgcgctttac gatcaactgc
    11401 tcagtaatct gcaactggcg atgtcggtct ttttctccgg cgatgtcacc agcgcccgtc
    11461 ggttgcgccg cagtaaacat cgcttccgta tacttaatcg ccgatgctca catgcgcatg
    11521 tcgaccgcct gcaccagcag aacgtgcaaa gtattgaaac cagctcgctc catttagggc
    11581 tgctgggcga tatgaagcgt cttaactcac tgttctgttc ggtcgcctat agcgtactgg
    11641 aacagccgga tcaggacgag gaacggggcg agtattaagt gaaatgccgg atggcggtgt
    11701 aaacgtcttc cggcctacgg aaaacatgcg cgtaggcccg ccattcggca ttcaatgtgg
    11761 cctgggatta aaagcgatga cccgcttcca gcgccacggc ctcttcgccc gctttaaaca
    11821 cccaggtggt attcgggccg ccgagaaccg cttggccgtt gctcacctga atccagttgc
    11881 cttccggcaa accaatcact gtcagttccg gcgcgaccac cagcagttcg cgaatatgct
    11941 gctcgcgggt ctcgccctta tgaccctccg gcaaggcgtt agtgaagtga ggattaattt
    12001 gcagcgggaa cagatccagc gcgtcgaaac cgtttggatc gacgatcggc atatcgttgg
    12061 tcgtgcggat agtcgggcag gcaaggttgg cgcccgcgct ccagccgata tacagcgcgc
    12121 cgcgttttac cctgtccgcc accggcgcca gcagcccgcg ttcacgcgat tctttcagta
    12181 gctggaaggt atttccgccg ccgacaataa cgatttccgc tttctcaatc gccgcaagcg
    12241 gatcggcgac acgatgaatc cctgtgacgt ttatccctaa tggcgcaagc acctctgcgg
    12301 ttttatccgt gtactcgtcc catgtttgcg tgacgccggc aaacggaata aacacggctg
    12361 agcgtcgacc gttcaactga ttcgctatca gcggcagagc gtgttccagc caggctttac
    12421 ccggcagcgt cgagttactt aataaaagca gttccattat ttctccacct catcaggaaa
    12481 tgtcaaaacg taataatgct accattatcc atttaatgtc ttactgatat ggctcatgat
    12541 gttgcgcgtg ttacaggcaa cgcgcggtcg ctaaaagtga cgccaggcca gatctgccat
    12601 ctggtatcgc ctgaaaaatt acaggtataa tccgcaaaat tatttaacac gtttagagac
    12661 gaaaatggca aaactgacct tacaagagca actgctacaa gcgggattag tgaccagcaa
    12721 aaaaatggcc aaagtccaac gcacggctaa aaaatcacgc gttcaggctc gtgaggccag
    12781 agaagcggtg gaagaaaata aaaaggcgca acttgagcgt gataaacaac tcagtgaaca
    12841 gcaaaaacaa gcggttttag cgaaagagtt taaagctcag gttaagcaac ttattgaaat
    12901 gaatagaatc aatgtatcta aaggcgatat tggttttaac ttcaccgata ataacgtcat
    12961 caaaaaaata gacgtggata agcttaccca gacacaactg attaatgggc gtctcgcgat
    13021 tgcgcgtctg gttatcaata acagcggtga atgtgaatat gcgattattc ccgcgagcgt
    13081 cgccgataaa atcgcacaac gagatgcgga cagtattgtc gtaaacagtg cgctgagtca
    13141 ggaagagcag gacgaagatg atccgtatgc cgattttaaa gttcctgacg atttgatgtg
    13201 gtaagtcaca ttcccaacgt ttatgtagaa aaatttctca gagagtaaat atgctgaccg
    13261 acacatctac ccggcttaat aaatatatca gtgaaagcgg catctgttcg cgtcgcgagg
    13321 cggaccgttt tatcgaacag ggcaatgtct ttatcaacgg caaacgcgcc gccattggcg
    13381 atcaggtggt cgccggggat gttgttaaag taaatggtcg gttgattgag ccgcgagaag
    13441 cggatgattt agtgctgatt gcgctgaata aaccggttgg cattgtcagt accactgaag
    13501 acggcgaacg cgacaatatt gtcgattttg tgaaccacag caaacgtatc ttcccgattg
    13561 gtcgtctgga taaagactcg caggggctga tatttctgac taaccacggc gatctggtca
    13621 ataagattct gcgtgccggt aacgatcacg aaaaagagta tctggtgacg gtggataaac
    13681 cgattaccga cgagtttatt cgcggtatgg gcgctggcgt gccgattctg ggtaccgtca
    13741 ccaaaaaatg taaggtgaaa aaagaggcgc cgtttgtctt tcgcattacc ctggtgcagg
    13801 gattaaaccg tcagatccgt cgtatgtgtg aatactttgg ttatgaagtg acgaaactgg
    13861 agcgtacgcg cattatgaac gtcagcctga gcgggattcc gctgggcgag tggcgcgatc
    13921 tgacggacga tgagctgatc gatctgttta aattgattga gggttcctct tccgaagcca
    13981 aaccaaaggc caaagcgaag ccgaagaccg cgggtattaa gcgaccggtc gtggcgatcg
    14041 aaaaaagcaa tgagaaagcg cgcccggcat caagcggtaa gcgctttacc tcgccgggac
    14101 gaaagaagaa aggacgttaa cgtctgccgc gcgtcggcgt attcgccgac caggagaatg
    14161 acgcttccgt atcgggttta tacgcctgct ttttcttcaa ctggcgggct tttttcgctt
    14221 cagcctcacg cagcgccatc agcttatcga tgtactcctt ttttacgctg ttggtctcag
    14281 aattggtcag cggacgcccg tgcgcaatac gggcgcggtc cagcaacgtt ttcagttcgc
    14341 gctgttcgcg ctcggtcatc tctttttggg taatgcgggg gagtgccata cgggtgccct
    14401 cagttagccg atgcatttag tctacggcaa tacgcaacgg gcggatagcg ctcagtcagc
    14461 aatccgcagc tttccagcga aatcctgtgg cgtataaccc gttgacgtaa atcctttatc
    14521 cgtgatgatg ttatcgattt cttttacgct tgcgatgcac atcacaccgt cctgaccaaa
    14581 tttggtatgg tcagcgagaa tcactgattt tttgctcatc gcaatcatgg ctttggcaac
    14641 gtaggcttct tcaaagctct tcaccaacac gccatgctgg ggagaaatgc cgccagcgcc
    14701 aataaaacag atatccgcgt gaatcgcgtt aatctgctga cataccgaga cgccgagatt
    14761 agcgcgaaaa tggtaatcat attcgccgcc taatacatac acgcgggcct gcaggttatg
    14821 ctctttaatt ttatcggcaa tcagtgctga attggtaatc acggaaaaag cgagaggcgg
    14881 taattgctcg gccagaataa ggttagttgt acaggaatca ataaacaatg tatcccgttc
    14941 actgatcatt tcggcggcaa gtttgccaat cgctattttc tcttcgcgat gcgcctctat
    15001 tcttgcgcta aacgcatctt cctggacaac ttgctttttg accgcgcccc catgaatctt
    15061 agtgattttg ccttctgatt ccagtaagga gagatcgcga cgaatggttt ccgaggtgac
    15121 gttgagcatt tccgataatt taataacggt gacttcaccg aatttgttta attcatcaag
    15181 aatatgtttt cgtcttttaa ttggattcat tatctttcgc cgctgtcaac ctttggcgca
    15241 tggtaactgg atgcgtaagg caacgcaacc actccaacgc atggacgata ccctcctcat
    15301 cattcgtggc agtcacatag tcggcctgcc gctttactgc atccggcgcg ttgcccattg
    15361 cgatgctgat tccggcggcg gcaaacatgc tgacatcatt ctgctgatcg ccaatcacga
    15421 ccaccttgtc agaagatata tttaaataat gaattaattg ttctattatg caccctttat
    15481 ttacatcggt tctttgaata tcaatataat tttctcccgt gacgaccgca taatatccat
    15541 aaggcaggtg attattcact tctgtacaca gtgtatctat c
//
LOCUS       DAJVKX010000105        15571 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.105, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000105 DAJVKX010000000
VERSION     DAJVKX010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15571
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.105"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            115..1218
                     /locus_tag="OPY25_003304"
     CDS             115..1218
                     /locus_tag="OPY25_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase small subunit"
                     /protein_id="HCS0928840.1"
                     /translation="MQTQDTFYQVMRRHGVTRRSFLKFCSLTATSLGLSSSMIPQIAY
                     ALENKPRTPVIWLHGLECTCCTESFIRSAHPLAKDAILSLISLDYDDTIMAAAGQQAE
                     QALADVMREYKGNYIVAVEGNAPLNEDGMFCILAGEPFLEKLKRVSADAKAIIAWGSC
                     ASWGCVQAARPNPTKATPVHKLITDKTIIKVPGCPPIPEVMSAVITYMLAFDRIPPLD
                     RLGRPKMFYGQRIHDKCYRRAHFDAGQFVEAWDDEGARKGYCLYKMGCKGPTTYNACS
                     TVRWNDGVSFPIQSGHGCLGCSEDGFWDYGSFYSRATGIPQTGIEATADKIGLGVAGV
                     AGAAAIAHATVSAIKHARNKNNTSSENATEKKK"
     gene            1221..3023
                     /locus_tag="OPY25_003305"
                     /pseudo
     CDS             1221..3023
                     /locus_tag="OPY25_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent hydrogenase large subunit"
     gene            2974..3717
                     /gene="cybH"
                     /locus_tag="OPY25_003306"
     CDS             2974..3717
                     /gene="cybH"
                     /locus_tag="OPY25_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase, b-type cytochrome subunit"
                     /protein_id="HCS0928841.1"
                     /translation="MLLIIMEGSWSGFRYDDDDSEVSMHLKEITSQGYYIYEAPVRLW
                     HWITALSIVVLAVTGYFIGRPLPSIQGEATFMFWMGWIRLIHFTTAYIFTVALLFRIY
                     WACVGNEYAREMFLVPFWRRAWRKGVISEIRWYFFLEKEAHRYYGHNPVAGLAVMFYF
                     WMSVLMVCSGFALYGEGLGTDSWAYQWFGWMIRLTGNDSLALHFWHRLGMWFIIAFVI
                     AHVYTAIREDIMSRQSVISVMISGWRWFR"
     gene            3723..4331
                     /gene="hybD"
                     /locus_tag="OPY25_003307"
     CDS             3723..4331
                     /gene="hybD"
                     /locus_tag="OPY25_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HCS0928842.1"
                     /translation="MAEVTILGLGNLLWADEGFGVRAAEKLFEQYADNEKVDVVDGGT
                     QGLALLPWLQQTEKLLIMDAIDFGMAPGSLAMFRDEQVPAYLTAKKLSLHQTSFSEVL
                     ALLQLTGGQLSEIVLIGVQPECLDDYGGSLTPQVRAQLMPAVYLAQEVLAQWGITASS
                     AALPTERLNHYSLCMERYEDERPDAQSACRVGDIRVLQREKS"
     gene            4331..4630
                     /gene="hypC"
                     /locus_tag="OPY25_003308"
     CDS             4331..4630
                     /gene="hypC"
                     /locus_tag="OPY25_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="HCS0928843.1"
                     /translation="MCIGVPVQVISPGQWFAKCRDRHGELIDVDIRLVAPPLAGAWLL
                     TFGGAARREMDEAEAVEVLVALDSLEQAMLTQSDPLTGFADLLSRTPELPEHLKK"
     gene            4627..5037
                     /locus_tag="OPY25_003309"
     CDS             4627..5037
                     /locus_tag="OPY25_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase"
                     /protein_id="HCS0928844.1"
                     /translation="MTISPQNPVCPLADKGFLVTDAQTLPSLINAHPTLLVLLQSDPN
                     KHPEVADSWVIIPEILKQFPATSYTAAFADSEQSELIAREYRILKYPALLFFRQHRFV
                     GSLAGLYSWQEYSQRVAALLTTPGYRQDIPVITQ"
     gene            5055..6116
                     /locus_tag="OPY25_003310"
     CDS             5055..6116
                     /locus_tag="OPY25_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HCS0928845.1"
                     /translation="MNHSRTIPVVNIAGPGSQPEEEDFNFLPIPAGINLPLTPVLPEQ
                     ALPAELRVARHILTTLIRDMDNPVATLPFPLSYKLNATEQQNSGLLDQLLGEGEISAR
                     VLLSDGKEQRIQETVFTGVWRVREYNADQQRVADEIIIGPIPESIWQTHPQPPITPEL
                     PPQLAGLMNGAFIAHEIAERVKQPVKEPHIINLTLLPVNDADREYLDHFLGEGCSAIF
                     SRGYGKCRIVSTHFPGVWRVNYFNDMNTLLQDMIEIADIPDIAVAGIDDIEDAYTGLK
                     NTLEWLKEYPVTENEPVVRMECKVCWWVYDPALGDDVWQIPPGVPFNQLPDYWCCPVC
                     ETSKSGFMVIDEGNNSCKD"
     gene            6104..6874
                     /locus_tag="OPY25_003311"
     CDS             6104..6874
                     /locus_tag="OPY25_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
                     /protein_id="HCS0928846.1"
                     /translation="MQRLTVYSHPLWITWQEAPIGRLLQGATPVYAKTLISRLFTLCA
                     QAHNAAAALLLFPEEKPDMQAAQQELARETLRRALTDWLPLFSHRQATAEEWALLRRG
                     ELSPLASTIFFDDDPQTWLAAGVKGWEAWFLQERSETARWLAAVQNIITPTLPMASSP
                     GHTLITHGPLDVSPLAIEYPLLSACCLSGKTTALRLLARCITLARSLSALPTLRWNRF
                     DDGEWKIAVVETARGWLVHQARLTTSGNITKFRQYVSP"
     gene            complement(6842..7258)
                     /locus_tag="OPY25_003312"
                     /pseudo
     CDS             complement(6842..7258)
                     /locus_tag="OPY25_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460490.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
     gene            7976..8518
                     /locus_tag="OPY25_003313"
     CDS             7976..8518
                     /locus_tag="OPY25_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HCS0928847.1"
                     /translation="MGITIMQKTSLFFSAAAITLTLMASSASAATPTAAQNEATSTVK
                     QEITESINRYLYSIDKADPTLGKQLFYVSPETSFIHPRGHERGWSQIAENFYGTTMGK
                     TFSKRTLKLDAPPAIHVYGNAAVAEFDWHFTAVRRDNGQTQHTTGRESQVWAKIPNTG
                     WRIVHVHYSGPAKTGVGEGY"
     gene            complement(8574..9488)
                     /locus_tag="OPY25_003314"
     CDS             complement(8574..9488)
                     /locus_tag="OPY25_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HCS0928848.1"
                     /translation="MIVRPQQHWIRLIFVWHGSVLSKIFSRLLLNFLLSIAVIIMLPW
                     YTMLGIKFTLAPFSILGVAIAIFLGFRNNACYARYVEARHLWGQLMIASRSILREVKT
                     TLPDERGIEDFVRLQIAFAHCLRMTLRRQPQTQVLGNYLDQEALQKVVASHSPANRIL
                     LLMGEWLAIRRRSGKLSDILFHSLNNRLNDMSSVLAGCERIANTPVPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFIALDALAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDERDIPAKRIPDKRYQLT"
     gene            complement(9744..10103)
                     /locus_tag="OPY25_003315"
     CDS             complement(9744..10103)
                     /locus_tag="OPY25_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HCS0928849.1"
                     /translation="MNALEPLFARLARSTFRSRFRLGIKERQYCWDKGAEVIDKHAAD
                     FIAQRLVPAHPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHQIPQGEPLSKAQQQ
                     YIVSVIHYWLVIQMNQR"
     gene            complement(10103..11029)
                     /gene="glsB"
                     /locus_tag="OPY25_003316"
     CDS             complement(10103..11029)
                     /gene="glsB"
                     /locus_tag="OPY25_003316"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HCS0928850.1"
                     /translation="MARAMDNAILETILQRVRPLIGQGKVADYIPALASVEGSKLGIA
                     ICTVDGQHYQAGDAHERFSIQSISKVLSLVMAMRHYPEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVARALCGVSDITYDATVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVPTVLQNYFHYCALKMSCMELARTFVFLANQGEA
                     FHLDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDPAGNSLAGIAALEQLTQTLGRLVY"
     gene            complement(11102..12490)
                     /gene="sad"
                     /locus_tag="OPY25_003317"
     CDS             complement(11102..12490)
                     /gene="sad"
                     /locus_tag="OPY25_003317"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HCS0928851.1"
                     /translation="MTMMTATQALSVNPATGQTLAAMPWANAQEIEHALSLAASGFKK
                     WKMTSVAQRAQTLRDIGQALRAHAEEMAQCITREMGKPIKQARAEVTKSAALCDWYAE
                     HGPAMLNPEPTLVENQQAVIEYRPLGVILAIMPWNFPLWQVLRGAVPILLAGNSYLLK
                     HAPNVTGCAQMIARILTEAGTPAGVYGWVNANNEGVSQMINDPRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFIV
                     EEGIAQAFNDRFVAAAAALKMGDPLVEENDLGPMARFDLRDELHQQVQASVAEGARLL
                     LGGEKIAGEGNYYAATVLADVTPDMTAFRQELFGPVAAITVAKDAEHALALANDSEFG
                     LSATIFTADDTLAAEMAARLECGGVFINGYSASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNVQTVWKNRV"
     gene            12593..13465
                     /locus_tag="OPY25_003318"
     CDS             12593..13465
                     /locus_tag="OPY25_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0928852.1"
                     /translation="MDLTQLEMFNAVALTGSITQAAAKVHRVPSNLTTRIRQLEADLG
                     VSLFIRENQRLRLSPAGHNFLRYSQQILALVDEARMVVAGEEPQGLFSLGALESTAAV
                     RIPALLAGYNQRYPKIQFALTTGPSGAMLDGVLEGKLNAAFIDGPLMHPGLEGIPAYQ
                     EEMMIVAPHGHSVVSRASEVNGYNIYAFRANCSYRRHFESWFHADGATPGTIHEMESY
                     HGMLACVIAGAGIALMPASMLNSMPGHHQVEAWPLAEKWRWLSTWLMWRRGAMTRQLE
                     AFIELLNAQLASAD"
     gene            13581..14771
                     /locus_tag="OPY25_003319"
     CDS             13581..14771
                     /locus_tag="OPY25_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCS0928853.1"
                     /translation="MTINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFH
                     MQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKLLICLFVLFIASHVLSFLAWNFT
                     VLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVV
                     GQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLT
                     VVVVTAHYTAYSYIEPFVQNVAGLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSL
                     VSIAIALLVVCLLLLLPAADSEAHLAILSIFWGIAIMVIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGAIPACAALVWAVLIFRKWPVTLE
                     EQPH"
     gene            complement(14818..15483)
                     /locus_tag="OPY25_003320"
     CDS             complement(14818..15483)
                     /locus_tag="OPY25_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family NAAT transporter"
                     /protein_id="HCS0928854.1"
                     /translation="MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     YMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHESP
                     EAKSKSEELADEPTANIAFVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAP
                     PIIFLAVAVILWGCLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIK
                     TYH"
BASE COUNT         3804 a         4065 c         3940 g         3762 t
ORIGIN      
        1 catgtaatca gttgttacga attagaaaca taattgctac taaaacacgt tgagaaagac
       61 aagaaatgca acatatgatg cccacactaa ctatagtggt ttgggataaa cgttatgcaa
      121 acacaagata cattttatca agttatgcgt agacacggcg tgacaaggcg tagcttcctc
      181 aagttttgca gccttaccgc aacgtcttta ggcctgagca gttcgatgat tcctcagata
      241 gcttatgccc tggagaataa accgcgtacg ccagtgatat ggctgcatgg tcttgaatgt
      301 acctgctgta ccgaatcttt cattcgctct gcgcacccgt tggcaaaaga tgccattttg
      361 tcgctcattt ccctggatta tgacgacacc attatggccg ccgcagggca acaagccgag
      421 caggcgttgg cggatgtgat gcgtgagtac aaaggaaatt atatcgttgc cgtggaaggt
      481 aacgcgccgc tgaatgaaga tggaatgttt tgcatactgg ctggcgagcc gttcctggaa
      541 aagttaaaac gcgtcagcgc ggatgctaaa gcgattatcg cctgggggtc ctgcgcatca
      601 tggggctgcg tgcaggcagc ccgtcccaac ccaactaaag ccacgccggt tcacaaatta
      661 attaccgata aaaccattat taaagtgcca ggctgtccgc ctatacctga agtgatgtcc
      721 gccgttatca cctatatgct ggcatttgat cgcatccctc cccttgatcg tcttggacga
      781 cccaaaatgt tttatggcca gcgaattcat gacaaatgtt accgacgcgc gcatttcgat
      841 gccggtcagt ttgtggaagc gtgggatgac gaaggcgcca gaaaagggta ttgcctgtac
      901 aagatgggct gtaaaggccc gactacctat aacgcctgtt caaccgttcg ctggaatgat
      961 ggcgtgtctt ttcctatcca gtcgggtcat ggatgcctcg gatgttcgga agatggattc
     1021 tgggattacg gttcttttta cagccgggca acgggcattc cgcaaaccgg cattgaggct
     1081 accgccgata aaatcggact gggcgttgcc ggcgtcgcgg gcgctgctgc catcgctcac
     1141 gccacggtta gcgccataaa acacgcccgc aataaaaaca acacgtcatc agaaaacgct
     1201 acggaaaaga aaaaataatt atggcatatc cttatcagac tcagggtttt acgctggaca
     1261 atagcggacg gcgaattgtg gtcgatccgg ttactcgcat cgaagagcat atgcgctgcg
     1321 aagtgaatat tgacagtaat aatgtcatta ctaacgccgt gtcgaccggc accatgtggc
     1381 gcggcctgga ggttaccctg aaaggtcgcg atccgcgaga cgcctgggca tttgttgagc
     1441 gcatttgcgg cgtctgcacc ggtacacacg cgctgacctc aatccgtgcc gtagaaaatg
     1501 cgctgggaat cgcgattccg gacaacgcaa actgtatccg taatatgatg caggctacgc
     1561 tacacgttca cgatcacctg gtgcattttt atcatctgca tgcgctggac tgggtcgatg
     1621 tagttgccgc cctgaaagcc gacccgcatc agacctccgc catcgcgcaa agcctttccg
     1681 catggccgct atcctcgccg ggatatttcc gcgatttgca aaatcgactg aagcggttta
     1741 tcgagtccgg ttaacttggc cctttccgta acggctactg gggacatccg gcgatgaaac
     1801 ttccaccgga agccaatttg ctggcggtcg cccactatct tgaagcgctc gattttcaaa
     1861 aagagatcgt aaaaattcac accgttttcg gtggtaaaaa cccgcatcct aactggctgg
     1921 tgggcggcgt tccttgcgcc atcaaccttg acgaaacggg cgcggtcggc gcagtgaata
     1981 tggagcgcct gaaccttgtc agttccatca tccaaaaagc tcgccagttc tgcgaacaag
     2041 tttatcttcc ggacgtcttg ctgattgcca gttattacaa agactgggca aaaatcggcg
     2101 gcgggttatc gagcatgaac ctgctggctt atggcgagtt tccggataac cctaacgatt
     2161 attccgccag taatcttctg cttccgcgtg gggctatcat taacggtcgt ttcgacgaaa
     2221 ttcatcctgt cgatttaacc gcccccgatg agattcagga gtttgtcact cactcctggt
     2281 atacctatgg taacggcaat aacgataagg gcctgcatcc gtgggatggt ctgaccgaac
     2341 cgcaactggt catgggcgaa cactataaag gcacaaaaac ctttatcgaa caggtggatg
     2401 agtccgccaa atattcatgg attaaatcgc cgcgctggaa gggacatgcg atggaggtag
     2461 gtccgctggc gcgttatttg attggatatc atcaaaataa accggaattt aaagaaccag
     2521 tggatcaact gcttagtgta ttaaagctgc ctaaagaagc gctcttttct acattagggc
     2581 gtactgccgc gcgtgcgctg gaatccgtat gggcaggcaa tacgctgcaa tatttcttcg
     2641 atcgtctaat gcgtaacctc aagtccggcg atacggcgac ggcaaacgtt acgctctggg
     2701 aacccgatac ctggcccaca tcggcaaaag gcgttggttt cagcgaggcg ccgcgcggcg
     2761 cgctggggca ctggataaaa attgaaaatc agaaaatcga cagctatcag tgtgtggtac
     2821 cgacaacctg gaatgccggg ccacgtgacg ataaaggtca aattggcgcg tacgaagcag
     2881 cgttaatggg gactaaactc gccgttcccg atcaaccatt gaagatttta cgtactctgc
     2941 acagcttcga tccctgcctg gcctgctcca cccatgttat tgataatcat ggaggggagc
     3001 tggtcagggt tcaggtacga tgacgacgat tcggaggtct caatgcatct caaagaaata
     3061 accagccagg ggtactatat ctatgaagcg ccggtccgtt tatggcactg gatcacggcg
     3121 ttatccattg tcgtcctggc tgttacagga tatttcattg gccgccccct gccatcgatt
     3181 caaggtgaag cgacctttat gttttggatg ggctggatac gactgatcca ttttaccacg
     3241 gcgtatattt ttactgtcgc gctgctgttt cgtatttact gggcatgtgt cggcaatgag
     3301 tacgccaggg agatgtttct ggttccattc tggcgccgcg cctggcgcaa aggcgttatc
     3361 agcgaaatcc gctggtattt tttcctcgaa aaagaggccc atcgttacta tggacataat
     3421 ccggtagcgg gactggcggt aatgttctat ttctggatgt ccgtactgat ggtgtgtagc
     3481 ggctttgcgc tctatggcga aggacttgga acagacagtt gggcgtatca atggtttggc
     3541 tggatgattc gcctgactgg caacgatagc ctcgcgctgc atttctggca ccggctgggc
     3601 atgtggttca ttatcgcctt cgtcattgcg catgtttata ccgctatccg cgaagacatt
     3661 atgagccgac aaagcgtgat ttccgtcatg ataagcggct ggcgctggtt caggtgataa
     3721 caatggcaga agtaacaatc ttagggcttg gcaacctgct ttgggcagat gaagggttcg
     3781 gcgtcagagc tgcggaaaag ctgtttgaac agtatgccga taacgagaaa gttgacgttg
     3841 ttgatggcgg tacgcagggg ctggcgctgc tgccctggct gcaacagaca gaaaaactgt
     3901 taatcatgga tgctatcgat tttggtatgg cgccaggttc gctggcgatg tttcgtgatg
     3961 aacaggttcc cgcctatctg acggcgaaaa aacttagttt acatcagacc agtttttctg
     4021 aagtgctggc attgctgcaa ttaaccggcg gccagttatc ggagattgtg ctgattggcg
     4081 tgcagccgga atgtctggat gactatggcg ggagtcttac gccgcaggta agggcgcaac
     4141 tgatgcctgc ggtctatctc gcgcaggaag tgctggcgca atggggtatc accgcctctt
     4201 cagcggcctt gcccactgaa agactcaatc attacagcct gtgtatggaa cgctacgaag
     4261 atgaacggcc agatgcgcaa agcgcttgcc gggtcggcga tattcgggtg ctacagagag
     4321 agaaatcata atgtgtattg gcgttcctgt gcaggttatt tcacccggtc agtggttcgc
     4381 caaatgccgc gaccgacacg gcgagcttat cgacgttgat attcggcttg tggctccccc
     4441 cttagcaggc gcatggctgc tgacatttgg cggcgcagcg cgacgagaaa tggacgaagc
     4501 ggaagccgtt gaggtactgg tggcgctgga ctcgctggaa caggccatgc tcacgcaaag
     4561 cgatccgctg accggttttg ccgatttatt gtctcgcacg cctgaattac cggagcattt
     4621 aaaaaaatga ctatctcacc ccaaaatcct gtttgtccac tggcggataa aggctttctg
     4681 gttaccgatg cgcaaacgct cccgtcgttg attaatgcgc atccgactct gctggttttg
     4741 ctgcaaagtg accccaacaa acatccggaa gtcgccgaca gttgggtcat tatcccggag
     4801 atcctcaagc aatttccggc gacatcttat accgcggcat ttgcggatag cgaacagagt
     4861 gaactgatcg cccgggagta tcgcattctg aaatatccgg cgctgctttt ctttcgccag
     4921 caccgttttg tcggcagtct ggcgggatta tatagctggc aagaatactc tcagcgggtg
     4981 gccgcattgc tgactacacc gggctatcgt caggatattc ccgttattac gcaatagaat
     5041 gaaaggtaac acacgtgaat cattccagaa ctattccagt cgttaatatt gccggaccag
     5101 gatcgcagcc agaagaggaa gactttaact ttcttcccat ccccgccggc attaatctcc
     5161 cgctgacgcc ggttttaccg gaacaggcgc tgcccgctga gctccgtgtt gccagacaca
     5221 tcctgactac gcttattcgc gatatggata acccggtggc aacgctcccc tttcccctga
     5281 gctataagct gaatgccact gagcaacaga atagcggttt attggatcaa ctgctcggcg
     5341 aaggtgaaat ctccgcccgg gtactattat ccgatggaaa agaacagcgt attcaggaga
     5401 cggtttttac gggcgtctgg cgtgtacgtg aatataacgc tgaccagcaa cgggttgccg
     5461 atgaaattat cattggcccg atcccggaga gcatctggca gacgcatccg cagccgccga
     5521 ttacaccaga attgccgcca caactggcgg gattgatgaa tggcgccttt atcgcgcatg
     5581 aaatagccga gcgcgtaaaa cagccggtaa aagagccgca tatcattaat ttaacgctat
     5641 tgccagtaaa cgatgccgat cgcgagtatc tggatcattt tttaggcgaa ggctgtagcg
     5701 ctattttttc acgcggatat ggtaaatgcc ggattgtaag cacgcatttt cccggcgtat
     5761 ggcgggtcaa ttatttcaat gatatgaaca cattactgca agatatgatt gagatagcgg
     5821 acattcctga tatcgccgtt gcaggcatcg acgatatcga agatgcctac acggggctaa
     5881 aaaatacgtt ggaatggttg aaagaatacc cggtcacaga aaatgagcca gtggtgcgca
     5941 tggagtgcaa agtatgttgg tgggtttacg accctgcgct gggcgatgat gtatggcaaa
     6001 ttccacccgg cgtgcccttc aaccagttac ctgattactg gtgctgtccg gtttgcgaaa
     6061 ccagtaagtc cgggtttatg gtgatcgatg aaggtaataa ttcgtgcaaa gattgaccgt
     6121 ctattctcac ccgctatgga ttacctggca ggaggcgccg atcggtcgtt tgttacaggg
     6181 cgcaacgccg gtatacgcaa aaacgcttat ttcacgtttg tttacgttgt gcgctcaggc
     6241 gcacaacgca gcggcggctt tactgttgtt tcctgaagag aagccagata tgcaggccgc
     6301 acaacaagag ttggcgcgag aaacgctccg tcgcgcgttg accgactggc tccccctgtt
     6361 tagccaccga caggcaaccg ctgaagaatg ggcgttgtta cgtcgcggag agttatcccc
     6421 gctggcaagc acaatctttt ttgacgatga tcctcagacc tggcttgccg ctggcgtaaa
     6481 gggctgggaa gcctggtttt tgcaagagcg ttctgaaacc gcccgctggc tggcggcagt
     6541 acagaatatc attacaccta cactaccgat ggcgtcgtcc ccgggccata cgttaataac
     6601 ccatggtccc ctggatgtct cgcctctggc tatcgaatat ccgctgctgt cagcctgttg
     6661 tcttagcgga aaaacgactg cgctacgtct gctggcccgc tgcattacgc tcgcccgaag
     6721 tttgagcgcc cttcctaccc tacgctggaa tcgttttgat gatggcgagt ggaaaatagc
     6781 agtagtggaa accgcgcgag gatggttagt tcatcaggcc agactgacga cgtcaggtaa
     6841 tattaccaaa ttcaggcagt acgtcagtcc atgaaccaat gtcgtataac acgccatagt
     6901 tacgaccata atcaacagac cccatatcgg caaatgccaa accagcaaaa ccgagacgcg
     6961 tccagctttg cggggaaccg ctggagtcac catcttccgg acgattggcg ttgacctgat
     7021 actcccactg tccaaaaccg gttagttgat cggtaatttg agtctcgcct ttaataccca
     7081 tacggatata agattgatcg ccatccgtac tatgattact ggaaaaataa tgcaggccgt
     7141 cgaccttgcc atacaaatcc agtttattgc catccttgtt atagatttct gctgcgttgg
     7201 cggctccagc catcatcacg gctgcggcta ccgcagataa caccactact tttttcattt
     7261 tatatgcctt atttgtctta tttttggact ttccgcaaaa cctgctcgcg gaactgtccg
     7321 ggacaatatc actaacaatt accgtgcgtt aagtttcaaa gtgtaatatt agcttgctat
     7381 gtattagtga tgttaaaatg caagttaagc atggctacat caatggtgtg ccctgttttc
     7441 tgctgtaata acaagggggt gaccagtaga gaactggctt acggtcgggg atgccgaggt
     7501 gagaatggca ctgaacactc tgctgacact tcattaagac ggaatcataa tcaagtcagt
     7561 tgaggccaca gcccttctta tttttgtgta taatttgtta cgtttacatt tatttttaaa
     7621 ttagcgttat gaaaatatca gtactactga aatagcactt cttcgcttcg cgtattttta
     7681 ctatggttaa ttatcacata gcgcaaacgg tcatttgtgt atcactattc ataagattaa
     7741 ctatttacca gtggtaataa acataaaagt aagtcaaggg acaacaacaa tactgaaact
     7801 ctaaatgttg atattttgag tcatgccgtt acaaacaaat acgatattct taattgcact
     7861 actccctttt cggggtagtt ttatagaagg atgtttttta ttgttcgaga gccatgctcc
     7921 tttagtataa aggtgaacgt aacaggaaag ataaagcgtc tcaaaaacag accatatggg
     7981 tataactatt atgcaaaaaa cgtcactatt tttttcagcc gccgcgataa cgttaactct
     8041 gatggcgtca tcggcatcag cggcaacgcc aaccgccgca caaaatgaag ctacgtcgac
     8101 cgttaaacaa gaaattacag aaagcattaa ccgttacctt tattcaatag ataaggcaga
     8161 cccaacgtta ggcaagcagc ttttttatgt ttcaccggaa accagtttta ttcatccacg
     8221 cggtcacgaa cgcggatggt cgcagatcgc tgaaaatttt tatggcacca ctatgggtaa
     8281 aacgttcagc aaacgcacgt taaaactgga cgctcccccg gctattcatg tgtatggcaa
     8341 tgccgccgtt gcagagttcg actggcattt taccgcggta cgccgtgata atgggcagac
     8401 tcaacacacg acaggccgcg aaagccaggt atgggcgaag ataccaaaca caggatggcg
     8461 aatcgttcat gtccactact ccggtccagc caaaaccggc gttggagaag gctattaagc
     8521 tttgcttttc aggttatggc gcagatgaac attctgcgcc agttaagacg aactcaggtc
     8581 agttgatagc gcttatccgg tatccgtttt gccggaatat ccctttcatc attcatttgc
     8641 agtaaatcga tttctatcgc attgcatatc gcatccagcg gtaaatcatt attttcagta
     8701 ccgaacggat cttccaactc ttccgctaac gcatccagcg cgataaacgt ataagaaatc
     8761 agcaccgaaa taaacggcgt catatagtgc agatcaacca ccagtgcaaa tggcaacata
     8821 atgcagaaaa gataaaccgt acgatgcaaa attaacgtat aggcaaaagg caccggcgtg
     8881 ttggcgatgc gctcacagcc ggccaacact gacgacatat catttaagcg gttgttgagg
     8941 ctatgaaata aaatatcgga aagctttccg ctgcggcggc gaatcgccag ccactctccc
     9001 atcagcaata agatacggtt agcgggggaa tgggaagcga caactttctg taacgcctcc
     9061 tggtcaagat agtttcccag aacttgcgtt tgaggctgtc gacgcaatgt catacgcaaa
     9121 cagtgggcaa aagcgatttg taaccgaaca aaatcctcga taccgcgttc atcaggcaag
     9181 gttgttttca cctctcgcag tattgagcgt gaagcgatca tcaactgccc ccacaaatgt
     9241 cgggcttcga cgtaacgcgc ataacaggca ttattgcgaa acccaagaaa aatggcgata
     9301 gcgacgccca gtatgctaaa cggcgcaagg gtaaacttaa tacccagcat tgtgtaccag
     9361 ggcagcatga taataacggc gatagaaaga agaaagttaa ggagcagtcg tgaaaagatt
     9421 ttagataaca cggaaccatg ccagacaaat atcaggcgaa tccagtgctg ttgtggtcta
     9481 acgatcatga ttatcttcag caggtgaaaa agcactgtca ttaaacgtga tccagatcaa
     9541 ggttgcaagc ttctggtgat acacggattc cctgctctgt agaacatttt tttgcatggt
     9601 gctgacaggc gttggaaaaa aacaaccaaa tgtatgttgt aactaaaaag acatttcagc
     9661 acatgagata tatgacggtc aacggctgct atcagtggta tagggtgatt tatcggggaa
     9721 agcgtcagca acgacgcgct accctaccgc tgattcattt gtatgaccag ccagtaatga
     9781 ataacgctga caatatactg ttgctgcgct ttactcagcg gttctccctg aggaatctgg
     9841 tgccacttcg ccaggcaccc gcgacagcag gttgccgtcg catgttgcgc gataaatacc
     9901 ggatggcccc gcatcggcgt ttgcttacca tcattcgccg ggtgagctgg caccagtcgc
     9961 tgggcgataa aatcggcggc gtgtttatca atcacctccg cgcctttatc ccagcaatat
    10021 tgtctttctt ttatcccgag acgaaagcgc gaacgaaatg tcgatcgcgc caggcgggca
    10081 aagagcggtt caagcgcatt catcagtata ccaaacgtcc taacgtttgt gttaattgtt
    10141 caagcgcggc gatacctgcc agagagtttc ccgcaggatc cagctccgga ctccagacgg
    10201 caatcgccat ttcatgcggc acaatggcga caataccgcc gcccacgccg gatttagcgg
    10261 gcaatcccac ccgccaggca aactcgccgg cattctgata cataccgctg gtcgccatta
    10321 gcgcattaat ctgccgggcc tgcatggggg taactaccgg ctcgtcgaga tgaaacgcct
    10381 cgccctgatt cgccagaaag acaaacgtcc tcgccagttc catgcagctc attttcaacg
    10441 cacagtagtg gaagtaattt tgcaacacgg taggcacatc atgatgaaaa ttaccgaatg
    10501 atttcatcag ccaggcaata gcggcgttac gggcggaatg ctcaaattca gagcgcgcga
    10561 ccgtagcgtc atatgtaata tccgatacgc cgcaaagcgc gcgcgcaact tccagcatcc
    10621 gctgacgcgg cgcgctaagc cgcccttgca acatgtcgca taccaccagc gcgcccgcat
    10681 taataaatgg attacgcggg atgccttgtt ccatctctaa ctgaaccaac gaattgaacg
    10741 gcgagccgga aggatctttt ccgacacgct gccagatctc ctcttccgga taatgacgca
    10801 tcgccatcac cagactgagc actttcgaaa tagactgaat agagaagcgt tcgtgcgcat
    10861 cgcccgcctg ataatgctgc ccgtccacgg tacaaatcgc tattcccagc tttgaaccct
    10921 cgacggacgc taatgccgga atatagtcag ctactttgcc ctggccaatg agggggcgaa
    10981 cgcgctgtaa aatcgtttct aaaattgcat tatccatggc cctggccaca acatgctcct
    11041 tgctcgcagg tctgaaaagg cctgcgagta tagcagaggg cgccacgcga cgtcagggcg
    11101 attagacgcg gttcttccag acggtctgca cattacaaaa ttcgtgtaaa ccaaagtgcg
    11161 aaagctcgcg accgaagccg cttttcttca ccccgccgaa tgccacacgc gcatcgctgg
    11221 cgctgtaccc attaatgaat accccaccgc actcaagacg cgccgccatc tccgcggcca
    11281 gcgtatcgtc ggcggtaaag atcgtcgccg acaggccaaa ctcactgtca ttcgccagcg
    11341 cgagggcgtg ctccgcatct tttgcaacgg taatggcggc aacaggccca aaaagctcct
    11401 gacgaaatgc cgtcatgtca ggagtgacat ccgccagaac ggtcgcggca taatagttgc
    11461 cctccccggc gattttctcg ccgcccaaca gtagccgtgc gccttcggcg acggaagcct
    11521 gcacctgttg atggagttca tcacgcaaat caaagcgcgc catcggcccc agatcattct
    11581 cttcaaccag aggatccccc atctttaatg ctgcggcagc cgccacaaaa cgatcgttaa
    11641 acgcctgcgc aatgccctct tcgacaataa aacgtttggc ggcggcgcag acttgtccgg
    11701 tgttttgata gcgtccggca accgcggctt ttaccgccag ctcgagatcg gcatcattga
    11761 gtacaataaa cggatccgag ccacccagtt ccagtacgca ctttttcagc gccgccccag
    11821 cctgagcgcc aatcgccgcg ccggcgcgca cgctaccggt caccgtcacc gccgcgattc
    11881 gcggatcgtt aatcatctga ctcacgccct cattattggc attcacccat ccatagacgc
    11941 cagcgggagt accggcttcc gtcaagattc gggctatcat ctgcgcgcaa cccgtgacat
    12001 tgggcgcatg ttttaacaag tagctattcc ccgccaacag tatcggcact gccccgcgta
    12061 acacctgcca taaaggaaaa ttccacggca ttatcgccag aatgacgccc agcggacggt
    12121 attcaatcac cgcctgctga ttttctacca gcgtaggctc aggattcagc attgccggac
    12181 catgttccgc ataccagtcg cataacgcag cggatttcgt cacttccgca cgcgcctgct
    12241 ttataggctt acccatttca cgcgtaatac attgcgccat ctcttctgca tgagcgcgaa
    12301 gcgcctgacc aatatcgcgt aatgtttgcg cccgttgcgc taccgatgtc attttccact
    12361 ttttgaaacc gctcgccgcc agactcagcg catgttcaat ctcttgcgcg ttagcccagg
    12421 gcattgccgc cagcgtctgg ccggtcgcag gattaacgga taacgcctgt gttgcagtca
    12481 tcatggtcat gttctttctc tcgttatcag gggagttgta ccatcatgac gccctttacc
    12541 ctttctgaaa aatgaataat attaaccaga ctattcacga attgagaaaa ccatggacct
    12601 gacgcaactg gaaatgttta acgctgtcgc tctgacgggc agcattacgc aggcggcggc
    12661 aaaagtgcac cgcgttccgt ccaatctgac cacgcgtatc cgccagcttg aagccgacct
    12721 gggcgtctct ctgtttattc gcgaaaacca gcgactcagg ctgtcaccag ccgggcataa
    12781 ctttttacgt tacagccagc agatcctggc gctggttgat gaagcccgta tggtggttgc
    12841 cggagaggaa ccgcaaggac tgttttcact cggcgcgtta gaaagtactg ccgccgtacg
    12901 tatccccgcg ctgctggcgg gttataacca gcgttaccct aaaattcagt tcgcgttaac
    12961 gaccggtcct tccggcgcca tgctggatgg cgtgctcgaa ggaaagctga acgccgcctt
    13021 tattgatggc ccgctaatgc atccggggct ggaaggtata ccggcttacc aggaagagat
    13081 gatgatcgtc gcgccacacg gccattccgt cgtttcgcgg gccagcgagg tgaatggtta
    13141 taacatctat gcttttcgcg ccaactgttc ttaccgacgg catttcgaaa gctggtttca
    13201 tgccgatggc gcgacccccg gtacgattca cgaaatggag tcatatcatg gaatgttggc
    13261 gtgcgtaatt gccggcgcag gtattgcgct gatgccagca agtatgctca acagtatgcc
    13321 aggacatcat caggtggaag cctggccgtt ggcggagaag tggcgctggc ttagcacctg
    13381 gctaatgtgg cgacgcgggg cgatgacgcg tcaacttgag gcctttatcg agttacttaa
    13441 cgcccaactg gcgagcgccg actgaagacg aaacggcctg cgaagtaaat gagaagcagg
    13501 tcacaaaatg attgtctttt cgccagtaaa cgttttaaga tcgcggtctc accttctcgc
    13561 aactaacccg aaatattttt atgacaatca atccagtttc ccgcaaggtc gcgtggctac
    13621 gggtagttac gcttgctatt gccgctttta ttttcaatac cacagaattt gtgccggttg
    13681 gtttgctatc agacattgct gaaagctttc atatgcaaac cgcgcaggtc ggcatcatgc
    13741 taaccattta cgcctgggta gttgccgtta tgtcgctgcc ttttatgctt cttaccagtc
    13801 aaatggagcg ccgtaagcta ctcatttgtc tgtttgtttt gtttattgcc agccatgtgc
    13861 tctcctttct ggcatggaac tttaccgtgc tggtcattag ccgtattggt atcgctttcg
    13921 cccacgctat tttctggtcg ataaccgcct cgctggcgat ccgcctggcc cctgccggga
    13981 aacgcgcgca ggcattaagt ctgatagcga ccggcaccgc gttggccatg gtgcttgggc
    14041 tgccgatagg tcgcgttgtt ggtcagtatt ttggctggcg caccaccttt tttgccatcg
    14101 gcatgggcgc attaattacg ctgctatgtc tgattaagct tctaccgaaa ttgccgagcg
    14161 agcattccgg ctcactaaaa agtttacctt tgctattccg gcgcccggcg ctaatgagcc
    14221 tctatgtact aaccgtcgtt gtggtgactg cgcattacac agcttatagc tatattgaac
    14281 cgttcgttca gaatgtcgcc gggctcagtg cgaattttgc taccgtcctg ttactgatcc
    14341 tcggcggcgc cgggatcatc ggcagccttg tgtttggtaa actgggtaat cgtcatgcct
    14401 cgtcgctcgt cagtatcgct attgccctgc tggttgtctg tctgcttctg ctgctgcctg
    14461 cggcggatag cgaagcgcat ctggccatac tgagcatttt ctggggcatc gcgattatgg
    14521 tgatagggct tggtatgcag gtgaaagtac tggcgctggc cccggacgcg accgatgtcg
    14581 caatggcgct attttcaggc atctttaata ttggtattgg cgctggcgcg ctggtaggca
    14641 atcaggtgag tttgcactgg tcaatgtcgg ccatcggcta tattggcgcc atacccgcct
    14701 gtgccgcgct ggtatgggct gtgctcatat tccgcaaatg gccagtgacg ctggaagaac
    14761 aaccgcatta agacattcgt ctgccgggaa caggtttccg gcagacgaca atgcgcctta
    14821 gtggtacgtt ttaataattt ccaacacgcc gttgataata aattgcacgc ccatacacac
    14881 cagcaggaat cccattaagc gggagatcgc ttcaatcccc cctttaccca ccagccgcat
    14941 aatagcgcca gaactgcgta agcatcccca caggatcacc gccacggcaa gaaaaataat
    15001 cggcggcgcg accataatga cccagtcggg aaactcgccg ccatgacgca ccgtggaagc
    15061 ggaactgatg atcattgcga tggtccccgg tcctgcggtg cttggcatag ccagtggaac
    15121 aaacgcaata ttggccgtcg gttcgtctgc cagctcctcc gatttgcttt tcgcttccgg
    15181 cgactcatgc gccttctgct gcgggaaaag cattctgaag ccgataaacg ccacgattaa
    15241 ccccccggcg atccgtagcc ctggaatcga aataccgaag gtgttcataa ctaactgccc
    15301 ggcatagtac gccaccatca taatagcgaa gacataaacc gaagccatat aggactgccg
    15361 gttgcgttcc gcactattca tattgcccgc aaggccaaga aacagcgcca cggtggttag
    15421 cggattggct aacgggagca gtacgaccag ccccaatcca atcgctttaa acaaatccat
    15481 cataatacta tctcttaccc atcagcgttt catgaaccgg aagtataaag tgaaattgcc
    15541 caggcgcgcc atttcgccag tgtgcaagtc a
//
LOCUS       DAJVKX010000106        15540 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.106, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000106 DAJVKX010000000
VERSION     DAJVKX010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15540
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.106"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..848
                     /gene="serB"
                     /locus_tag="OPY25_003321"
     CDS             <1..848
                     /gene="serB"
                     /locus_tag="OPY25_003321"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
                     /protein_id="HCS0928855.1"
                     /translation="FQKKLQETLFNAVTMPFPLLFDKRYAALINTAYLKLTLPAECLT
                     PEFYRYLRELSLQWQFDFFIKPQPLPANGIIAFDMDSTFIAEEGVDEIARELGMSTQI
                     TAITQQAMEGKLDFNASFTRRIGMLKGTPKAVLNAVCDRMTLSPGLLTILPVIKAKGF
                     KTAIISGGLDIFTQRLKARYQLDYAFSNTVEIRDNVLTDNITLPIMNAANKKQTLVDL
                     AARLNIATENIIACGDGANDLPMLEHAGTGIAWKAKPVVREKIHHQINYHGFELLLFL
                     IEDEL"
     gene            881..2203
                     /locus_tag="OPY25_003322"
                     /pseudo
     CDS             881..2203
                     /locus_tag="OPY25_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461143.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(2247..4238)
                     /gene="cirA"
                     /locus_tag="OPY25_003323"
     CDS             complement(2247..4238)
                     /gene="cirA"
                     /locus_tag="OPY25_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HCS0928856.1"
                     /translation="MFRFNPFVRVGLCMSAVTLAWPVAAATDDGETMVVTASAIEQNL
                     KDAPASISVITQQDLQRRPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     IDGKRVNSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWHGSVTVDSTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDEQQSS
                     ATTATGETPRIEGFTSRDGNVEFAWTPNENHDVTAGYGFDRQDRDSDSLDKNRLERQN
                     YALSHNGRWDLGNSELKFYGEKVENKNPGNSSPITSESNSIDGKYVLPLASVNQFLTF
                     GGEWRHDKLSDAVSLTGGSSTKTSASQYALFLEDEWRIFEPLALTTGIRMDDHETYGD
                     HWSPRAYLVYNATDTLTVKGGWATAFKAPSLLQLSPDWATNSCRGGCRIVGSPDLKPE
                     TSESWELGLYYRGEEGILEGVEASVTTFRNDVDNRISISRTPDVNAAPGYSNFVGFET
                     NSRGQRVPVFRYYNVNKARIQGVETELKVPFNEAWKLSLNYTYNDGRDVSNGGNKPLS
                     DLPFHTANGTLDWKPAQLEDWSFYVSGNYTGRKRADSATAKTPGGYVVWDTGAAWQAT
                     KNVKLRAGVLNVGDKDLKRDDYGYTEDGRRYFMAVDYRF"
     gene            complement(4584..6053)
                     /gene="lysP"
                     /locus_tag="OPY25_003324"
     CDS             complement(4584..6053)
                     /gene="lysP"
                     /locus_tag="OPY25_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HCS0928857.1"
                     /translation="MGSKTKTTEAPALRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     LAGPGGALFSYILIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMGWWFPDTPGWIWSALFLCVIFLLNYISVRGFGEAEYWFS
                     LIKVATVIIFIIVGVAMIIGIFKGVEPVGWSNWTTGDAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESENPEKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPNLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAIMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGYDVNDLPYRSGFFPLGPIFAFVLCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLLIWFGYKLIKGTHFVRYSEMHFPERVKK"
     gene            complement(6243..7106)
                     /locus_tag="OPY25_003325"
     CDS             complement(6243..7106)
                     /locus_tag="OPY25_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0928858.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLSLSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRVYASSTIGNY
                     ILPAMIARYRQHYPALPLELSVGNSQDVINAVLDFRVDIGLIEGPCHSTEIISEPWLE
                     DELVVFAAPSSPLTQGPVTLEQLAASPWILRERGSGTREIVDYLLLSHLPRFHMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIAEQLQAGTLGEVAVPLPRLVRTLWRVHHRQKHLS
                     NALQRFLSYCE"
     gene            7227..8276
                     /locus_tag="OPY25_003326"
     CDS             7227..8276
                     /locus_tag="OPY25_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HCS0928859.1"
                     /translation="MTELTLQNHRRTMWHFIPGLALSAVITGVALWGGAIPAVAGAGF
                     SALTLAILLGMVIGNTVYPQIWKQCDGGVLFAKQHLLRLGIILYGFRLTFSQIADVGI
                     SGIVIDVLTLSSTFMLACFLGQKVFGLDRHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTIAIFLYPAMYPLLAHWFSPETYGIYIGSTMHEVAQVVAAGHAV
                     SPDAENAAVIAKMLRVMMLAPFLIILAARVKQLSPATGAEKSKITIPWFAIFFIVVAI
                     FNSFHLLPKAVVDMLVTLDTVLLAMAMAALGLTTHVSALKKAGAKPLLMALALFAWLI
                     IGGGAINVLIHSLIA"
     gene            8355..9212
                     /gene="nfo"
                     /locus_tag="OPY25_003327"
     CDS             8355..9212
                     /gene="nfo"
                     /locus_tag="OPY25_003327"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCS0928860.1"
                     /translation="MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPL
                     TPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLG
                     LTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQ
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLN
                     DAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPDIWAEEIAWLK
                     AQQIAEAMA"
     gene            complement(9277..10965)
                     /gene="fruA"
                     /locus_tag="OPY25_003328"
     CDS             complement(9277..10965)
                     /gene="fruA"
                     /locus_tag="OPY25_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HCS0928861.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAAHKANLEIIDNPNDAELA
                     IVLGESLPNDNALNGKKVWLGDIGRAVAHPELFLSEAKSHATPYSAPAAAAPAASGGP
                     KRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAEADL
                     VIVAADIEVDLAKFAGLPMYRTSTGLALKKTAQELDKAVAEATPYQPAGKASQAATEG
                     KKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKVPDTLAAALMQIGGGSA
                     FALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYMAKLIST
                     KLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAVL
                     LGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYAPMAAIMAAGMVPPLALGLATMVA
                     RRKFDKAQQEGGKAALVLGLCFITEGAIPFAARDPMRVLPCCIVGGALTGAISMAVGA
                     KLMAPHGGLFVLLIPGAITPVLGYLLAIVAGTLVAGLAYAVLKRPETEVAAKAA"
     gene            complement(10982..11920)
                     /gene="fruK"
                     /locus_tag="OPY25_003329"
     CDS             complement(10982..11920)
                     /gene="fruK"
                     /locus_tag="OPY25_003329"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCS0928862.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFDVTPADWERFVNDSLSWLGQFDMVCVSGSLPAGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIDAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPAVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            complement(11920..13050)
                     /gene="fruB"
                     /locus_tag="OPY25_003330"
     CDS             complement(11920..13050)
                     /gene="fruB"
                     /locus_tag="OPY25_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HCS0928863.1"
                     /translation="MFQLSVQDIHPGEQAGNKEEAIRQIAAALAQAGNVAGGYVDGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPQGVTWGEGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNETMTLDVI
                     ASSLVTLQALNAARLKEAGAVDAAFVAKTINDSPMNLGQGIWLNDSAEGNLRSAVAVS
                     RATQAFDVEGEKAALLVTVAMNDEQPIAVLKRLGDLLLNNKADRLLSADAATLLALLT
                     SDDALTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSEITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGEDAEQALKAIGDAIAAGLGEGA"
     gene            13420..14601
                     /gene="setB"
                     /locus_tag="OPY25_003331"
     CDS             13420..14601
                     /gene="setB"
                     /locus_tag="OPY25_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HCS0928864.1"
                     /translation="MHNSPAAAAPKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPGMVGFFFTGSAVIGIIVSQFLAGRSDKKGDRKKLIVFCCVLGMLACVLFAWN
                     RNYFILLFIGVFLSSFGSTANPQMFALAREHADRTGREAVMFSSILRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWFFLPSMRKDAPLATGTLEAPRRNRRDT
                     LLLFVICTLMWGTNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRLLMCIAVVAGLCFYAGMLLAHAPATLLGLQLLNAIYIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTIRVGWIIAGSLAGIAAEIWNYHAVFWFALVMIVATMFCLARIKD
                     V"
     gene            complement(14666..15331)
                     /locus_tag="OPY25_003332"
     CDS             complement(14666..15331)
                     /locus_tag="OPY25_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928865.1"
                     /translation="MRGENSEIDLVDVSLFLIRKWLSIVIATFIFVAIGYVFVSVHHD
                     TKVVSITIKPNLDTPATYALCGYANDIQCKTTVILNQFSRFLPAEYKNKISFDAKNQL
                     VLFKAQGREESVNNIISTLKNSVDKMAAWYIDDGDIKRYSVHKNMLQTETYTKLSLLS
                     EAVKNNANIEVIDVAVTPKYKMRLVLVLCGLMGVIFSITGLLCKRALTEYRIEKKTMN
                     DRA"
     gene            complement(15333..15455)
                     /locus_tag="OPY25_003333"
     CDS             complement(15333..15455)
                     /locus_tag="OPY25_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928866.1"
                     /translation="MCGFYLMKKYTFAARAFIFTLVLLFVISVFGLTISVLKGM"
BASE COUNT         3638 a         4307 c         3834 g         3761 t
ORIGIN      
        1 cgtttcagaa aaaattacag gaaacgttat ttaatgccgt caccatgccg tttccgctat
       61 tatttgataa acgttatgcc gcgcttatca ataccgctta tttaaagctt acgctgccag
      121 cggaatgtct gacgcctgaa ttttatcgct atttacgcga actctcattg caatggcagt
      181 ttgatttttt tattaagccg cagccactgc ctgctaacgg tattatcgcg tttgatatgg
      241 actcgacatt tattgcggaa gaaggcgtgg atgaaattgc ccgcgagctt ggcatgtcga
      301 cgcaaatcac cgccattacc caacaggcga tggagggcaa gcttgatttt aacgccagtt
      361 ttacccgacg tatcggaatg ttgaaaggca caccgaaagc agtgctgaac gccgtatgcg
      421 atcgcatgac cctttcgcca ggcctgttaa ctattctgcc agtcatcaag gccaaaggat
      481 ttaaaaccgc gattatctcc gggggactgg atatattcac ccagcgtcta aaagcgcggt
      541 atcaactgga ttatgccttt tcgaatacgg ttgaaatacg cgataacgtt ctgacggata
      601 acattacctt gccgattatg aacgccgcaa acaaaaaaca gacgctggtt gacctggctg
      661 cccggttaaa tattgccacg gagaatatta ttgcctgcgg tgatggcgcc aacgatctgc
      721 cgatgttaga acatgctggc accggtattg cctggaaagc gaagccggtt gtacgggaaa
      781 aaatccacca tcagattaat tatcacggtt tcgaattgct tctttttctt attgaagatg
      841 aattataacg cgactcacct cgccggaagg gaattttaaa atgagtataa aaacatttat
      901 tttcagccag cccgataagc cgattgtaaa agagaaaaaa gagatagacc agacctataa
      961 aaaatttcgt tttgagatta tcgcctcggt ctttatctct tatgccgtct tttatcttac
     1021 ccgtaaaaac ttctccgccg cgatgccggc catgctgacg gaaacgtcgc tgaccgcaga
     1081 agacttcgcc attatgtctt ctatttttta cattctttat ggcgcgatga agtttgtcgg
     1141 cgggatgctg gtcgataaaa ttaacccgaa agccatgacc ggcccggtgc tgattggcgt
     1201 ggggattgta aatattctgt tcggcttttc cgacagcgtg gcggcattct acgtgctgta
     1261 cagtctcaac gcgatattac agggcaccag ctttccgccg atggcgaaaa ttatggcctc
     1321 gtggttttcg aaaaacgaac ggggacgctg gtgggctatc gttgaagcgg cgcacaatat
     1381 cggcggcagc ctcgcgccgc tgctgaccag ttttgctatc gcctttagcg gtagctggaa
     1441 aatgggattt tatgttcccg gcgccatttc gctgctgatg gggatagtgg cgctatttac
     1501 cattaaagat cgtcccggta cgttaggttt gcccaacgtg gggcagtggc gtaacgaccc
     1561 gacggaactg gcccaggtca aggccagccc ggtcaacctg agcttctggc agatttttgt
     1621 gaaatatatc ctgaccaatc cactggtatg gatcattatt atcggtgata tgtcggttta
     1681 tattgcgcgc actattctta acgactggcc gcagatttac tattcgcagg ttcacggctg
     1741 gagtctgata aaagcgaact cgattatttc ctgatttgag gcgggcggac tggcaggtgg
     1801 gttgctggca ggctacttgt ctgactttat gttcaaaagt aaccgctgga tgaccgggtt
     1861 aatcttcgcg ttagcgctgt gcatatgcat cgtgctggtg ccgctggttc aggatacctc
     1921 ttacaccctc agcgcgattc tgttcaccat catgggcttc gccttatacg gaccgcatat
     1981 gctttttgcc gtcggctgtc tggatgtgac ccataaggat gcggcgggat cgattaccgg
     2041 ctttcgggga ttgttcagct atgtcggcgc ggcaatggcc ggtgtgccgg taattatggt
     2101 gaaaaatagc tgggcgtggt cgggcgttta tatctatgcg ttaatcgcca ttctgctaac
     2161 gactctgtcg ctggcgctgc tctccaggct gcatcggtta taacattctg gcgacagcgg
     2221 caaaacgcgg ctgtcgccag tctctgtcag aaacggtaat ccaccgccat aaagtaacga
     2281 cgtccgtctt cggtataacc gtagtcgtcg cgtttgagat ctttatcgcc cacgttcaga
     2341 acgcccgcac gcagtttaac gtttttcgtc gcctgccatg ccgcgccggt atcccagacc
     2401 acgtacccgc ccggcgtttt cgccgttgcg ctgtcggccc gcttacgtcc ggtataattc
     2461 cctgatacgt agaatgacca gtcttcaagc tgcgccggtt tccagtcaag cgtaccgttc
     2521 gcggtgtgga acggcagatc ggaaagcggc ttgttcccgc cattactgac atcgcgtccg
     2581 tcgttatagg tgtaattcaa cgacagtttc cacgcctcgt taaacggaac tttcaactcg
     2641 gtttccacac cctgaatacg tgctttattc acgttgtaat aacggaagac cggaacgcgc
     2701 tgtccccgac tgttggtttc gaagccgaca aagttggaat agccgggcgc ggcgttaacg
     2761 tcaggggtac ggctaatgct gatgcgattg tccacatcgt tacggaacgt ggtaacgctc
     2821 gcttccacgc cctccagtat gccttcttcg ccccggtaat aaaggccgag ctcccagctt
     2881 tcactagttt caggtttcag atccgggcta ccgacaatgc ggcatccgcc acggcaggag
     2941 ttggtcgccc agtccggact taattgcaat agcgacggcg ctttaaaggc cgtggcccac
     3001 ccacctttca ccgtcagggt atccgttgcg ttatagacca gataagcacg cgggctccag
     3061 tgatcgccat aggtttcatg gtcatccata cgaataccgg tggtcagcgc cagcggttcg
     3121 aagatgcgcc actcatcttc aaggaacaga gcgtactggc tggcggaggt tttagtactg
     3181 gaaccgccgg tcaggctcac cgcatcactc agtttatcgt gacgccattc gccgccgaag
     3241 gtgaggaact ggttgacaga cgctaacggc agaacgtatt tcccgtcaat cgaattgctt
     3301 tctgacgtga tagggctact gttgccgggg tttttgtttt ccaccttttc gccgtagaac
     3361 ttgagctcgc tattgccgag atcccaacgt ccgttatggc tcaacgcgta gttttgccgt
     3421 tccagtcggt ttttatccag cgagtcggag tcccggtcct ggcgatcaaa accgtagcct
     3481 gcggtaacgt catgattttc gtttggtgtc caggcaaact cgacgtttcc atcccggctg
     3541 gtaaatcctt caatgcgcgg cgtttcaccc gtagcggtgg tggcggaact ctgctgctcg
     3601 tctttttcgc gtttcgccag gctaccgtag gctttcattc ccagcacgcc gtcgatcagc
     3661 ggaccgctgg taaagaactg accgttatag gtatcgccac ggtcgcgatg ttcctgaata
     3721 gtggagtcaa ccgtgacgct gccgtgccat ttctgaccaa tttttttggt gataatgttg
     3781 accacgccgc ccagcgcatc ggagccatac agcgaggaca tggggccacg caccacttca
     3841 atgcgttcga tagcgtcaac cggtatccag ttcagatcaa aatcattatg gcggaagacc
     3901 gcgttacggg agttaacgcg cttaccgtcg atcaggatca gcgtataact gctgtccaga
     3961 ccacgaatac tcacgccttt acggttatcc ccttcgttag tgagctgtac gcccggcacc
     4021 tctttcagga catctttcag gttttgcacg ggcctgcgct gtaaatcttg ctgggtaatg
     4081 acgctgatac ttgctggcgc atctttcaga ttttgttcga tggcggacgc ggtaacgacc
     4141 atggtttcac catcatccgt tgccgcggca accggccagg ccaacgtaac tgcggacata
     4201 caaagcccta cccgaacgaa agggttaaac ctaaacattc catttctcca tgaggtaaat
     4261 acgacaaaaa aatcggttat cgctcacaac gcattacgtt tcgcctgcga taacggttat
     4321 cacggcgaac tctttttatg caggcgagtc gggctcatga gtgacggtcg cgcccgaatc
     4381 ttcatccttt ctgatttcga gcgtaacgat aaagtaaacg ataataatta tcaatttaat
     4441 tgttaataat tatgtcattt gaaccaatca taaagaaaaa acaaaaaacc ctctcgaatg
     4501 agagggttag aagggtcagg ttcaggcagt ccgtgccgga tggcggcata aagccttatc
     4561 cggcctatga cgagaatatt acgttacttt ttaacgcgtt ccgggaagtg catttcgcta
     4621 tagcgcacga aatgcgtgcc ttttatcagc ttgtagccga accagataag caggaacagc
     4681 ggaataccga tataggtcgc cgcgacgccg ccccagtcga tggtatcttt caggaacgct
     4741 tcatagttct gccccaacgt aataatcagg cacagtacaa aggcgaaaat cggccccagc
     4801 gggaagaacc cggaacggta cggcaaatca ttcacatcat acccttgtaa cacgtaaccg
     4861 cgacggaagc gataatggct aatggcaatc cccagccagg cgatgaagcc cgtcataccg
     4921 gaggtgttca acagccacag atagaccgtc tggttgccga acattgaggt caaaaagcaa
     4981 agaccggcaa tcacggtggt ggcataaagc gcattgcgcg gtacgccgcc gcgggacaat
     5041 ttcgcaaaaa tacgcggggc cttaccgtca caggccaggg tgtagagcat acgggtcgag
     5101 gcatacatcc cggagttacc cgcagacagt accgccgtca ggataaccgc attcattatc
     5161 gccgccgcag acaacaagcc cgcatgctgg aacactaagg taaacggact gacgctaatg
     5221 tctttgacgt cgttacgcag caggtttgga tcggtataag gaatgatcag gctgataatc
     5281 aaaatcgcga aaacataaaa cagcagaata cgccagaaca cctgacgcac cgcgcgcgga
     5341 atattcttct ccgggttttc agattccccg gcggcaatac caatcagctc agttccctgg
     5401 aaagagaagc ccacgatcat cgcgacgcca atcattgccg caaaaccgcc agcgaaaggc
     5461 gcatcgcccg tcgtccagtt gctccagccg accggctcga cacctttaaa gatgccgata
     5521 atcatcgcta cgccaacgat gatgaagata ataacggtcg cgactttaat taacgagaac
     5581 cagtactccg cctcgccaaa accgcgtaca gaaatgtagt tcagcaagaa aatgacgcag
     5641 aggaatagcg cgctccagat ccagcccggc gtgtccggga accaccagcc catcaccaat
     5701 tgtgcggcaa ccaggtcaac agcgatagtc accgcccagt tgtaccagta gttccagccc
     5761 agcgcgaaac caaagccttc ttccacatag ttctgaccat atgtcgcaaa cgagccagat
     5821 accggcatat aggccgccag ctcgccaaga ctggtcatca ggaagtagac catcaaacca
     5881 atcagaatat aagaaaacag cgcgccgcct ggccccgcca gagaaattgt cgcaccagat
     5941 gcaacgaaaa gacctgtccc gatggagccg ccaatggcaa tcatcgtcag gtgacgcgcc
     6001 tttaattcgc gacgtagcgc gggcgcttct gtggttttag ttttggaacc catgtgaaaa
     6061 tgctatccat ccaaaaaatg aggcgcgatt gtaacagacg aaatactatc cttccgacac
     6121 aaatgcgcgg ttataagaga ccttcatgac cggccacgga ttataagtaa agcagagaat
     6181 aacgtatacg taagcggata ctaaaaatgg cgatgccgct cgggcagccc tcctcttcac
     6241 ctttattcac agtaactcaa aaaacgctgc aacgcgttag aaagatgttt ctgccgatga
     6301 tgaacacgcc acaacgtgcg caccaggcgc ggtaacggca ccgcgacttc gcccagggtt
     6361 cccgcctgaa gttgttcagc aatcacccgg cgcgataaac agcttatccc cagtccatga
     6421 cgcaccgcat gtttgatcgc ttctgaattc cccaactcca tcgccatatg aaagcgcggc
     6481 aaatgcgaca acagcaaata atcgacaatt tcccgcgtac cggaaccgcg ctcgcgtaaa
     6541 atccatgggg atgccgcaag ctgttccagc gtcaccggcc cctgcgtcag cggcgaggac
     6601 ggcgcggcaa agaccaccag ctcatcttcc agccacggct cagagataat ctctgtactg
     6661 tgacacggcc cttcaatcag gccgatatca acccgaaaat ccaacaccgc gttaatcacg
     6721 tcctggctgt ttcccacgct gagttccagc ggcaaggccg gataatgctg gcgatagcgg
     6781 gcaatcatgg cgggtaaaat gtaattgccg atggtgctac tggcataaac ccgtatcgcg
     6841 ccgttatctt cacgaaatag ctgctcaatt tctaccgctt gctccagcaa tgccagcgcg
     6901 cgcgggtata acaagcgccc atgttcgttg accaccagcc gtttccccac ccgatcaaac
     6961 aactgtacgc cgagctgacc ttccagatcg gtgagcgcgg cgctaacggc ggactgcgat
     7021 aatgacagca tgaccgacgc ctgggttgtt gaaccgcttt tcagtacttc agcaaacact
     7081 tcaagttgtc gtagcgtaat atgcatagtc gtatcccacc gatagcgttt cacttaccac
     7141 ttataaagat taattataaa tatataatca attttatttt taaaccagat caccgtaacc
     7201 ttattgtcca tatacaggag aaggttatga cagaactcac cttgcagaat catcgtcgta
     7261 caatgtggca ttttataccg gggctcgctc tgagcgccgt cattacagga gtcgccctgt
     7321 ggggcggcgc tatccctgct gttgcaggcg cggggttcag cgccctgacc ctggctatcc
     7381 tgctgggtat ggttatcggg aataccgtct atccacaaat atggaaacaa tgcgacggcg
     7441 gcgtgctgtt tgcaaaacaa catttactgc gtttagggat tatcctttac ggcttccgcc
     7501 ttaccttttc acaaatcgcc gacgtgggta ttagcggtat tgtgattgac gtattaacgc
     7561 tttccagcac gttcatgctg gcctgcttct taggccaaaa agtctttggt ctggacaggc
     7621 ataccagctg gctgattggc gccggtagca gtatctgcgg cgcggcggcg gtactggcga
     7681 cagaaccggt ggtaaaagcg gaagccagta aggttactgt agccgtcgcg actgtcgtta
     7741 ttttcggcac catcgctatt ttcctttacc cggcaatgta tccgctgctg gcgcactggt
     7801 tcagcccgga aacttacggc atctatatcg gctcaaccat gcatgaagtc gcgcaagtgg
     7861 tcgcagcggg tcacgccgtt agcccggatg cggaaaatgc ggcagttatc gctaagatgc
     7921 tgcgtgtcat gatgctggcg ccgttcctga tcattctggc ggcacgcgtt aaacagcttt
     7981 ccccggcgac cggcgcggaa aaaagcaaaa ttaccattcc gtggtttgct attttcttca
     8041 tcgtagtggc gatcttcaac tctttccacc tgctgccgaa agccgtggtg gatatgctgg
     8101 tgacgctgga cacggtactg ctggcgatgg caatggcggc gttgggtctg accactcacg
     8161 ttagcgcatt gaaaaaagcg ggggcgaaac cgctgctgat ggcgctggca ttattcgcct
     8221 ggctgattat tggcggtggc gccattaacg tcctaatcca tagccttatc gcataaatta
     8281 ttacgtttca cgcctgttaa cccgttatca tagcgttcgt aatgaaccgt tagcgggttt
     8341 aacaggagtc ttttatgaaa tacatcggag cgcacgtcag cgctgctggc ggtctggcta
     8401 acgcccctgc ccgcgcggct gaaattggcg caacggcctt tgcgcttttc acaaaaaacc
     8461 agcgtcagtg gcgtgccgcc ccccttactc cccaggtcat tgatgacttt aaaatcgcct
     8521 gtgaaaagta tcatttctcg gcggcgcaaa tccttcccca cgatagttac ctgattaatc
     8581 tgggccatcc ggtcagtgaa gcgctggaaa aatcacgcga tgcctttctc gatgaaatgc
     8641 agcgctgtga acaactcggc ttaaccttgc ttaattttca tcccggtagc catctgatgc
     8701 agattgcaca ggaggattgc ctggcgcgga tcgcggaatc tatcaatatt gccctcgcgc
     8761 agaccgaggg cgttacggcg gttatcgaaa atacagccgg tcagggcagt aatctggggt
     8821 ttgagtttga acagttagcc gccatcatcg acggcgtgga agataagtcg cgcgttggcg
     8881 tctgtatcga tacctgccat gcctttgccg ctggatacga tctgcgtacg ccagaggcgt
     8941 gcgaaaaaac gttcgccgaa ttcgggaaaa ttgtcggatt tcagtatttg cgcggaatgc
     9001 accttaacga cgccaaaagc gccttcggta gccgcgttga ccgccatcac agtctgggtg
     9061 aaggcaatat cggccacgat gcgtttcgtt ggattatgca ggatgcgcgt tttgacggta
     9121 ttccgctgat actggagacc atcaatcctg atatctgggc ggaagagatt gcgtggttaa
     9181 aagcccagca aattgccgaa gcgatggcct gacgctcaat gttcttcagg caataaaaaa
     9241 ggcagagcgc gctctgcctt ttttagcgtg tttctcttat gccgcttttg ccgcgacttc
     9301 cgtctccgga cgtttcagga cggcataagc cagtcctgcc accagcgtac cggccacaat
     9361 tgccagcagg tatcccaata ccggcgtaat tgcgcctggg ataagcagaa caaacagacc
     9421 gccatgcggc gccatcaatt ttgcgcctac cgccatagaa atagccccgg tcaacgcgcc
     9481 gccaacgata cagcacggca gtacacgcat cgggtcgcgc gccgcaaacg gaatagcgcc
     9541 ttcagtgata aagcacagcc ccagcaccaa cgccgcttta ccgccttcct gctgcgcttt
     9601 gtcgaactta cgacgcgcca ccatcgtcgc cagacccagc gctaacggcg gtaccatacc
     9661 tgcggccatg atcgccgcca tcggcgcgta agtttgcgta ctcagcagac caacgccaaa
     9721 cgcatacgcc gctttgttca ccgggccgcc catgtcggta cacatcatcc cgccgagaat
     9781 cgcgcccaac agcaccgcgt ttgccgtccc catggtttgc agccagtggg tgagcccttc
     9841 cagaatcccg gcaaccggtt taccgatcag gtaaatcatc gccagcccca ccaccagact
     9901 ggaaattaac gggatgatca ggattggctt cagcgcttcc atactttgcg gaagtttcag
     9961 tttggtactg ataagcttcg ccatataccc ggcaaggaag ccggcaatga tcccgccgat
    10021 aaaaccggaa ccggtgctaa ccgccagcat accgccaatc agacctggcg taaggccagg
    10081 gcgatccgcg atggagaaag cgatataacc cgccagtacc ggcaccatca gcgcaaacgc
    10141 cgaaccgccg ccaatctgca tcagcgccgc cgccagcgtg tccggcacct taaaggcttc
    10201 aataccaaag gcgaaggaaa gcgcaataca cagtcccccg gcaaccacca taggcagcat
    10261 gtaagaaacg cccgtcaaca gatgccggta tgcgccagcg ctctctttct tcccttcggt
    10321 cgccgcttgc gatgccttac ccgccggttg atacggcgtc gcttccgcta cggctttatc
    10381 cagctcctgc gccgtctttt tcagcgccag gccggtcgac gtgcggtaca tcgggagacc
    10441 ggcaaacttc gccagatcca cttcgatatc cgccgccaca atcactaaat ccgcttccgc
    10501 cacctcttcc ggggtgatgg cattgccggc ccccacggag ccgcgcgttt cgacttttac
    10561 ccaccagccg cgttttttcg cttctgtttc aatggcttca gccgccataa aagtatgggc
    10621 gacgccggtc gggcaggccg ttaccgcgac cacgcgtttc ggaccgccgc tcgctgcagg
    10681 agcagccgca gcaggggcgc tgtaaggggt cgcatggctt ttggcttcac tcagaaacag
    10741 ttccggatgc gcgacggcgc gaccaatatc ccccagccaa acctttttgc cgttcaaagc
    10801 attgtcgttc ggcagagatt cgcccagcac gatcgccagt tcagcatcat tcggattgtc
    10861 gataatttcc agatttgctt tatgcgccgc cgctccaagc agggttttcg ccatgtaagc
    10921 gcgagcctgg ccgagattag cgtcaattat cagcagcgtt ttcattatgc ctctcctgct
    10981 gtcagttaaa cggttgtaag tcgacacgcg ccatcattgc ggccaactga ggacgatcgg
    11041 taatacccac attgctctgg ctgaccgcca gcgcggcaac cgccgtcgcc agacgcagcg
    11101 tatgttcgct ggactcgcgc atcagcaggc cgtaaatcaa tccgccaacc atggaatcgc
    11161 ctgcgccgac ggtacttacc acgtcaaccg ccggtggttt agcgatccat tctcctgagg
    11221 cgttaaccca cagcgcgcct tccgccccca gcgaaatcac cacatgagcg ataccctgtt
    11281 cgcgtaacgc gtgcgccgca tcaatcacat ctttcatttc cgggagctta cgacccgccc
    11341 aaatttccag ttcgcggcga ttcggtttca ccagccacgg cgcagcttta agaccggcga
    11401 ctaacgcttc acggctacta tcaaagataa tgcatggaca ctggctgcgc agacgcgtca
    11461 tccagtcggt gaacgcttcc ggactcacgc cagccggtaa gctaccgctg acgcagacca
    11521 tatcgaactg acccagccag ctcagggagt cgttaacaaa gcgttcccag tctgcgggag
    11581 tcacgtcaaa gccggaaaag ttgaagtcgg tcacttcgcc atctttttcc gtcagcttca
    11641 cgttgatgcg ggtccggccc tgaaccacct gaaagcggtt agcgataccc agttcgctga
    11701 ataattgctg aaaaccgtcc tggttatctt taccgagaaa accgccgaca gtgacgtcga
    11761 tgcctaagtc tttcagcact ttggcaacgt taatgccttt gcccgccgcg tgcagacccg
    11821 tggttttcac caggttcact tcgccgcgtt cgatttcagg gcaaaaccca accagatcgt
    11881 aagccggatt aagggtaatg gtggcgacac gcctgctcat tatgcgccct ccccaagacc
    11941 ggcggcgatc gcatcgccaa tcgctttcag cgcctgttca gcatcttcac cctgcgcggt
    12001 aaagcgcaga cgatggcctt tcttcacgcc taatgccacc actttcatca gactacgtcc
    12061 gtttgccggt ttgccggttc catcaaggtt tgtcacggta atttcactgt taaattgttt
    12121 aatcgtattc accagcatgg tgcccggacg ggcatggaga ccatgctcat tacgcactac
    12181 aaattccgcg ctcagtacgt catccgtcag cgcatcatca ctggtcagca acgccagcag
    12241 cgtcgcggcg tcagcgctca gcagacgatc ggctttattg ttcagcaaca ggtcgccgag
    12301 gcgttttagc acggcaatcg gctgctcgtc gttcatcgcg acagtgacta ataaggctgc
    12361 tttttcaccc tctacgtcaa acgcctgggt cgcgcggctt accgcaacag cactgcgcaa
    12421 attgccttcc gcgctgtcgt tcagccagat gccttgtccc agattcatcg gactatcgtt
    12481 aatcgttttt gcgacgaacg ccgcatcaac cgctcccgcc tctttcagac gcgccgcatt
    12541 tagcgcctgc aatgtgacca gcgagctggc gatgacatcc agcgtcatcg tctcgttatc
    12601 aagttttaat tgttcacttt gcttctcgcc catcagcaat gcgcgcagct cttccgccgt
    12661 tgtcgcggat ttcagctgtt cagccacgga gtcatcgctc agcacatgcg tcagctgacg
    12721 cagcaggcca aggtgttcgt ccgaactggc ggcaatacca atcgccacgt aggcgacctg
    12781 gccttctccc caggtaacgc cctgcggaaa ttgaaagacc tggacgccgg ttttcagcac
    12841 ctgatcgcgc gtgtctgttg taccatgggg aatcgcaata ccattgccaa gaaaggttga
    12901 ggtttgctgt tcgcgcgcca gcataccgtc aacatagccg cccgccacat tccccgcctg
    12961 cgctaacgca gcggcgattt gccgaatggc ctcttcttta tttccggcct gctcgcccgg
    13021 atgaatgtcc tgaaccgata actggaacat gtgtctcctc tcctgctgaa ttgaaacgat
    13081 tcagccacta tgagaaaaaa agcgccaatc tgagttatca aaaaaaccag atcgcgctga
    13141 aacgtttcaa gaaagtctgg atctttctgc ttcagcacgc aagaaaagtt accggttttg
    13201 tagcaatttt ttgaggtgaa gcacattttt tctccaacag accctcaata gctgacgcat
    13261 aaaaggcttc agcttttttc tttcagcttg cgtcagcacg cccttgtaac aaactggaat
    13321 gctattttga tttttcgtgt cgattttgat tcagacgcct gtttattttc tgacgggcag
    13381 cgtaaactcc gcctctcttc acaccactga tatagaaaca tgcacaacag tcccgccgcc
    13441 gctgcgccca aatcgtttga cctgacgtct accgcctttt tgatcgtcgc ttttctcacc
    13501 ggtattgctg gtgcgttaca gacgccgaca ctcagtattt ttctgacgga tgaggttcac
    13561 gcccgtcccg gcatggtggg tttctttttt accggcagcg cggttatcgg cattatcgtg
    13621 agccagtttc tggcgggtcg ctcagataaa aaaggcgatc gcaaaaaact gatcgttttc
    13681 tgttgcgtgc tgggcatgtt ggcctgcgtg ttgtttgcct ggaaccgcaa ctactttatt
    13741 ttgctgttca tcggcgtctt tctcagtagc ttcggctcta ccgccaaccc gcagatgttt
    13801 gcgctggccc gagaacatgc cgatcgtaca ggtcgtgaag cggtgatgtt cagctcaatc
    13861 ctccgcgccc aggtctcgtt ggcctgggtc attgggccgc cgctggccta tgcgctggcg
    13921 atgggtttta gctttacggt gatgtatttg agcgcggcgg tagcttttat cgtctgcggc
    13981 gtcatggtgt ggttcttttt accgtcaatg cgcaaagatg cgccgctggc aaccggcacg
    14041 ctggaagcac cgcgtcgtaa tcgccgcgat acgctgttgc tgtttgtcat ctgtacgtta
    14101 atgtggggga ctaacagcct gtatatcatt aatatgccgc tgtttatcat caatgagctg
    14161 catcttccgg aaaaacttgc aggcgtgatg atgggcaccg ccgccgggct ggagattccc
    14221 acaatgctga ttgcaggtta cttcgccaaa cggttgggaa aacgcctgtt aatgtgcatc
    14281 gccgttgtcg ccggactgtg cttttatgcg gggatgttgc tggcgcacgc accggcaacg
    14341 ttgctcggct tgcagttgct gaacgcgatt tacatcggca ttcttggcgg gattggcatg
    14401 ctctattttc aggatctcat gccaggccag gcgggttcag ccaccacgct gtataccaat
    14461 accattcgcg tcggctggat cattgccggt tcgttggcgg gaatcgccgc agaaatctgg
    14521 aattatcatg cggtcttctg gtttgcgtta gttatgattg tcgccaccat gttctgcctg
    14581 gcgcgtatta aagatgttta acttgcaagc ctgatacttt tactcttcga cacatttcag
    14641 cgcagaattt atttctgcgc gatgttcatg cgcggtcatt cattgtcttt ttctcaatac
    14701 gatattctgt tagcgccctc ttacataaga gaccggttat tgagaaaatt acgcccatca
    14761 gcccgcaaag gaccaacacc agccgcatct tatattttgg tgtaacagca acatctatca
    14821 cttcaatgtt agcattattt ttaaccgcct ccgacaacaa ggatagcttt gtatatgttt
    14881 ccgtttgtaa catattttta tgcacgctat aacgtttaat gtcaccatca tcgatatacc
    14941 atgctgccat tttatcgacg ctatttttca gggtggaaat aatattattg acgctttctt
    15001 ccctcccctg cgccttaaaa aggacaagct gatttttcgc gtcaaaactt attttatttt
    15061 tatattccgc aggcaagaaa cggctaaact ggttaaggat aaccgttgtt ttacattgaa
    15121 tatcattagc atagccacat aacgcatagg tagcaggcgt atccagatta ggtttgattg
    15181 taatactcac aacctttgta tcatgatgca cgctcacaaa aacatagcca atggcgacaa
    15241 aaataaaggt agcgatcacg atacttagcc attttcttat aaggaataag gaaacgtcga
    15301 ctaaatcaat ttcactattt tctccccgca tttcacatcc cttttaaaac gctaatagtc
    15361 aacccgaata ctgaaataac aaaaagcaac accagcgtaa aaataaacgc cctggctgcg
    15421 aacgtatatt tcttcataag ataaaaccca cacataagaa ttcgagtatt ttaaaggaaa
    15481 ataacaacac attcacactg gttatatcga tcggtaaata catcaatgat agatataaac
//
LOCUS       DAJVKX010000107        15300 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.107, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000107 DAJVKX010000000
VERSION     DAJVKX010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15300
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.107"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            347..691
                     /locus_tag="OPY25_003334"
     CDS             347..691
                     /locus_tag="OPY25_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCS0928867.1"
                     /translation="MYLNRFCYLLLISAAVGSIFTSYPVAMWFLLANVLTLAIYGVDK
                     TAARKTWRRVPESTLLVFGVVGGWPGAIVGQQLFRHKTQKQPFKTYFIASVIVSIVVT
                     VAIYRLYPFLSY"
     gene            complement(812..952)
                     /locus_tag="OPY25_003335"
                     /pseudo
     CDS             complement(812..952)
                     /locus_tag="OPY25_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460590.1"
                     /note="involved in bacterial survival in the host cell;
                     incomplete; partial in the middle of a contig; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island 2 effector protein SseJ"
     gene            953..2053
                     /locus_tag="OPY25_003336"
                     /pseudo
     CDS             953..2053
                     /locus_tag="OPY25_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460583.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            2102..3610
                     /locus_tag="OPY25_003337"
     CDS             2102..3610
                     /locus_tag="OPY25_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="HCS0928868.1"
                     /translation="MLNPSIPLVATRHGKIVGVVQEEIHIWRGIPYAAPPTGELRWRA
                     PQPVTPWQDVRQADCFSCASWQDITWCRELGGGDPGNFSEDCLYLNVWAPAVRHEPLP
                     VMVWLHGGGYTIGAGSLPPYDGQALAKRGAIVVTVNYRLGHLGFFAHPALEGEGAECI
                     HNFALLDQIAALRWVQDNIAAFGGDTQNVTLFGESAGARSVLSLMASPLAKGLFHKAI
                     IQSGYTLPDTPREVALKKGVALAEHLGLAHATAEQLRALPAETFWPLDAPFKIAPTPI
                     SGDVVLPHPMLETFFAAKQHPIPVMIGSNSDEASVLAVFGVDIAGQIQKMRRERRVGL
                     GLIRLLYPGVKGDEALGRQVCRDMVFTTLGYVVMQAQKRIGEPCWRYWFDYVAEAEHN
                     TYANSACHGNEIPYVFDTLTRAEPTCHYVNENDLAFASQVADYWVNFARHASRTRDVL
                     HGPVRWPASIRGRDRLLRIGLNKLAGFKVENRFMRARLALFKRVMKHHVSLE"
     gene            3830..5485
                     /locus_tag="OPY25_003338"
     CDS             3830..5485
                     /locus_tag="OPY25_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein"
                     /protein_id="HCS0928869.1"
                     /translation="MNRRRFIKGSMAMAAVCGSSGIASLFSQAAFAAESDIADGKIVR
                     FDFAGLQSMAQALAKKPWGGAPGPLPDTLANLTPQAYNSIQYDAAHSLWNGVANRQLD
                     IQFFHVGMGFRRRVRMFSVDTTTHLAREIHFRPELFKYNDAGVDTTQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDGQEEFPDFTAFW
                     FDTAKPGDTTFTVYALLDSASVTGAYKFVIHCEKTQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGNNERRVCDTIHPQIHDSDRLAMWRGNGEWICRPLNNPQKLQFNAYMDDNP
                     KGFGLLQLDRDFSHYQDVMGWYNKRPSLWVEPRSKWGKGAVSLMEIPTTGETLDNVVC
                     FWQPEKAIKAGDTLAFNYRLYWSAQPPVQSPLARVMATRTGMGGFPEGWAPGEHYPDK
                     WARRFAIDFVGGDLKAAAPKGIEPVITLSSGEAKQVEILYVEPFDGYRIQFDWYPTSD
                     STAPVDMRMFLRCQGEAISETWLYQYFPPAPDKRRYVDDRIMR"
     gene            5681..6256
                     /locus_tag="OPY25_003339"
     CDS             5681..6256
                     /locus_tag="OPY25_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenoid-binding protein"
                     /protein_id="HCS0928870.1"
                     /translation="MNIMKKSFLGALLSLGLLSAAHADVYKFDNTHTNAVFNIDRFQT
                     STNHGGFYAISGELKYQPEKQVAEMRVTIPVSALNTGVDAFDNHIRSSDILDAEKYPE
                     IVFKSTKWHFEDNKPVSIDGLLTMKGVTKPVTLTTTKFGCYMSPIFKAQVCGGDFVTQ
                     IDRTQWGVDYLVDMGMTKVVDIKIQAEAVKQ"
     gene            6268..7470
                     /locus_tag="OPY25_003340"
     CDS             6268..7470
                     /locus_tag="OPY25_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase"
                     /protein_id="HCS0928871.1"
                     /translation="MKTHHLIRVVASLAMLATSGLAYAEEYKASTDEKAIKMTNVASL
                     EARVQARMEKGAFGYIRGGAEDENNLRSNTESFDKKYIMPRVLQGIELKEIDLSTQLL
                     GIPLKTPIIQAPMAAQGLAHASGELATAKGMAQVGSIFSLSTYGNKTIEEVANVSGKN
                     PFFFQLYMSKNNQFNEFILAQAVKHGAKAIILTVDSPVGGYREEDIKNNFQFPLSFAN
                     LEMFARKNDDGSKTGKGAGISEIYAQAKQAFTPEDIAYVHRISGLPVIVKGIQSPEDA
                     EIAIQAGAAGIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRRGSHVFK
                     ALASGADIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQVKTTRL
                     LTEKDLPQ"
     gene            complement(7528..7962)
                     /gene="aac(6')"
                     /locus_tag="OPY25_003341"
                     /pseudo
     CDS             complement(7528..7962)
                     /gene="aac(6')"
                     /locus_tag="OPY25_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460578.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cryptic aminoglycoside N-acetyltransferase
                     AAC(6')-Iy/Iaa"
     gene            complement(7962..8753)
                     /locus_tag="OPY25_003342"
     CDS             complement(7962..8753)
                     /locus_tag="OPY25_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0928872.1"
                     /translation="MSQQRPDRIKQMLHYLWQHRHLSTQQAIELFGYAEATVRRDFHY
                     IASRYPGMVRGHGCIDFDDSTEDKEYVFDVKRTLQSEAKREIAALARTFIKDGDCFFL
                     DSGSTCLELAKCLVDAKVKVICNDIKIANELGGFPHVESYIIGGLIRPGYFSVGESLA
                     LEMINAFAVERAFISCDALSIETGITNATMFEVGVKTRIIQRSREVILMADHSKFDTV
                     EPHAVATLSCITTILSDSALPSAIARRYQQAGCRLIMSDPSSGAR"
     gene            complement(8769..9401)
                     /locus_tag="OPY25_003343"
     CDS             complement(8769..9401)
                     /locus_tag="OPY25_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3 epimerase family protein"
                     /protein_id="HCS0928873.1"
                     /translation="MILHPSLASADPLRYAEALTALHDAPLGSLHLDIEDTSFINNIT
                     FGMKTIQAVAQYSRHPLSFHLMVSSPQRWLPWLAAIRPGWIFIHAESVQNPSEILADI
                     RAIGAKAGLALNPATPLLPYRYLALQLDALMIMTSEPDGRGQQFIAAMCEKVSQSREH
                     FPAAECWADGGITLRAARLLAAAGAQHLVIGRALFTTANYDVTLSQFTAL"
     gene            complement(9413..9850)
                     /locus_tag="OPY25_003344"
     CDS             complement(9413..9850)
                     /locus_tag="OPY25_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCS0928874.1"
                     /translation="MINDVKWVQAQRHASDWRHALDIAVRPLITFGAAAPCYLDGIIE
                     NTLKWGPYYLIAPGIALPHARPEQGANHNQISVTTLSTPVAFGNADCDPIWLLLCASA
                     TDAEAHIRTIQRISQWLDSPESVAMLQDAPNDAALFAQLTALR"
     gene            complement(9982..10788)
                     /gene="sgcQ"
                     /locus_tag="OPY25_003345"
     CDS             complement(9982..10788)
                     /gene="sgcQ"
                     /locus_tag="OPY25_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA family protein SgcQ"
                     /protein_id="HCS0928875.1"
                     /translation="MSWLKEVIGTEKAVIAMCHLRALPGDPGFDTRKGMNWVIDRAHD
                     DLMALQNGGVDAVMFSNEFSLPYLTKVRPETTAAMARIIGQLMSEIRVPFGVNVLWDP
                     VASFDLAMATDAKFIREIFTGAYASDFGVWDTNVGETIRHQHRIGAGHVKTLFNIVPE
                     AAVYLGNRDVCSIAKSTVFNNNPDALCVSGLTAGARTDSAILKRVKDTVPDTVVLANT
                     GVCLENVEEQLCIADGCVTATTFKKDGVFANFVDQARVAKFMEKVRHIRQ"
     gene            complement(10802..12115)
                     /locus_tag="OPY25_003346"
     CDS             complement(10802..12115)
                     /locus_tag="OPY25_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCS0928876.1"
                     /translation="MFDYILSLGGTVFVPIIMIIIGLIFRIPWLQAVKAGVTVGIGFV
                     GMGLVIVMAIDSLSPPIKVMIERFGLTLHVFDVGAGPASGVGYATAIGAMIIPVIFLL
                     NVGMLVTRLTKTMNVDIYNYWHYAITGTVVQLMTGSLIYGVLGAICHAALSLKMADWT
                     TKRVQNIVGLEGISIPQGYGSSSVPLFVLLDAIYEKIPFMKGRNIDAQEIQKRYGMVG
                     DPVIIGVVLGLIFGLAAGEGFKGCATLMITVAAIMVLFPRMIRLIVEGLMPISDGARK
                     FFQKHFKGREVFIGLDTAVTLGHPTTIAVGLLLIPIMLILASILPGNKVLPLADLPVA
                     PFFICMATVIHRGDLIRTLLSGIIVMITVLLIATQFAPYFTDMALKGGFSFAAENAQI
                     TALSVGNMFGWSISELMSLGMIGVVIVVGIVASIILVLRKRELPE"
     gene            complement(12126..12407)
                     /locus_tag="OPY25_003347"
     CDS             complement(12126..12407)
                     /locus_tag="OPY25_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCS0928877.1"
                     /translation="MMKKILVACGTGMSTSTMIAQKLQDFLAEQGIAATTAQCCLNEI
                     PLNCNGMDLIVTSMRTHSDYGIPTLNGAALLTGINDDALKQEIKALLTQ"
     gene            complement(12404..13522)
                     /locus_tag="OPY25_003348"
     CDS             complement(12404..13522)
                     /locus_tag="OPY25_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCS0928878.1"
                     /translation="MTFSVQETLFSLLRLNGISGHESSIANVMQHAFEQQAKDVWRDR
                     LGNVVARYGSDKSDALRLMIFAHMDEVGFMVRKIEPSGFLRFERVGGPAQITMPGSIV
                     TLAGCSGDIMGCIGIKAYHFAKGDERTQPPALDKLWIDIGAKDKADAERMGIQVGTPV
                     TLYNPPHCLGNDLVCSKALDDRLGCTALLGVAEALASTPLDIAVFLVASVQEEFNIRG
                     IVPVLRRVRPDLAIGIDITPSCDTPDLQDYSDVRVNHGVGITCLNYHGRGTLAGLITP
                     PRLLRMLETTAHENNIPVQREVAPGVITETGYIQVELDGIPCASLSIPCRYTHSPAEV
                     ASLRDLADCIRLLTALANMSPEQFPIDPETGATQEARP"
     gene            13739..14278
                     /gene="rimL"
                     /locus_tag="OPY25_003349"
     CDS             13739..14278
                     /gene="rimL"
                     /locus_tag="OPY25_003349"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HCS0928879.1"
                     /translation="MVEIIPVSTTLELRAADESHVPALHQLVLKNKAWLQQSLDWPQY
                     VTSQEETRKHVQGNMLLHQRGYAKMYLIFCQDEMAGVLSFNAIEPINKAAYIGYWLDE
                     SLQGQGIMSQSLQALMTHYARRGDIRRFVIKCRVDNQASNAVARRNHFTLEGCMKQAE
                     YLNGDYHDVNMYARIIDAD"
     gene            complement(14275..15255)
                     /locus_tag="OPY25_003350"
     CDS             complement(14275..15255)
                     /locus_tag="OPY25_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928880.1"
                     /translation="MIKYRLSEEPRAFTYQVDGEKKSVLLRQVIAVTDFNDVKAGTSG
                     GWVDADNVLSQQGDCWIYDENAMAFAGTEITGNARITQPCTLYNNVRIGDNVWIDRAD
                     ISDGARISDNVTIQSSSVRGECAIYGDARVLNQSEILAVQGLTHEHAQILQIYDRATV
                     NHSRIVHQVQLYGDATITHAFIEHRAEVFDFALIEGNKDNNVWICDCAKVYGHARVIA
                     GTEEDAIPTLRYSSQVAEHALIEGNCVLKHHVLVGGHAEVRGGPILLDDRVLIEGHAC
                     IQGEILIERQVEISGRAAVIAFDGNAIHLRGPKVINGEDRITRTPLVGSL"
BASE COUNT         3684 a         3847 c         4088 g         3681 t
ORIGIN      
        1 gggataaaat tctcaaatta acatcgtaca tcttatgtaa taaacataaa tacgataaat
       61 aaatccaaaa ctgagactgc caaccggata acaaacagca ataaagaggg ctctccatta
      121 agttatcctg gcaatggtta aggtggtaac atttttggtg gctttaccca ttttaatcgt
      181 gttcacaaca cgttaattac cttatgatta ccatggtaat taaaaatgaa tcctcgatga
      241 ctcgatgact cgttggctga atgaaaagaa aattctgcat cacataggcg catgtatcgc
      301 gtataatggg ctccgatgtc cctaatcatt gctatgacat aataatatgt atcttaaccg
      361 cttttgttat ttactcctga tctctgctgc ggtcggaagc atttttacat cgtatcccgt
      421 cgcgatgtgg ttcctgctcg ccaatgtgct aacgctggcg atctacggtg tagataaaac
      481 ggcggcacgt aaaacctggc gcagagtgcc ggaatccact ttgttggtgt ttggggttgt
      541 cggtgggtgg cctggtgcga ttgttggtca acaacttttc cgtcataaaa cgcaaaagca
      601 gccattcaaa acatacttta tcgccagtgt gatagtgagt attgtagtta cggtggcgat
      661 ctatcgactc tatccatttt tgtcctactg aacatagagt atggatcact tattgaccaa
      721 ccggcagcaa agacaacctc atattttcat gtcaccggca ctatgatatt gagcggtgtt
      781 ttgctcaagg cgtaccgcag ccgatggaac attattcagt ggaataatga tgagctataa
      841 aactttctaa cattgtggca aaacaatgat ggacttcctg ggttggatgg acaaagtcat
      901 tgaagacgta ttgcggacat atatctagct gagggtcttt agccccggga acttgcgtcg
      961 gatattcgcc atcatgggga tgtacccagt aagttattac gatctctctc aggcgggcgt
     1021 gcctgtgcac tccacggcat ttcgtcccat tgacgaggct tcgctctcgc gtaatccctt
     1081 tcgcatgttc acttcgctat tacgcctgga gctcattgaa aacgcggcat tacgccagcg
     1141 ggcggcggaa atcttatcgc agcgtgatat ttttacatcg cgctgccgac aattgctgga
     1201 tgagtacgac gagcagggcg gttttagtgc tgctcaggcc gaagagttcg tccgtgaaac
     1261 gctggagact tttcgctggc atcgtcaggc taccgttgat gaagaaacgt accgcagcct
     1321 gcatcgtgag catcgtttaa ttgccgacgt ggtctgtttt ccgggatgcc acattaacca
     1381 tctgacgccg cgtactctgg atatcgaccg ggtacaggcc atgatgccgg agtgcggcat
     1441 tacgcctaaa attcttatcg aaggtccgcc tcgccgcgaa gtgcctattc tgttgcggca
     1501 aaccagtttc aaagctctgg aagagcaggt gctcttcgtt gatgaaaagc agggtacgca
     1561 cacggcgcgc ttcggcgaaa ttgagcaacg tggcgtcgcg ctgacgccaa aaggtcgtcg
     1621 attatatgac gaactgttgc acaaggcggg aacgggtaag gacaacttca cgcatcaact
     1681 ccatttgcgg gaggtcttta acgcctttcc ggatagcgaa tttctgcttc gcctgcaggg
     1741 gcttgcctgg ttccgttatc gcttaacgcc ttccggcgag gcgcatcgtc aggcgatcca
     1801 tcctggcgac gatccgcagc cgcttattga gcgcggttgg gtgatcgcgc agccgattac
     1861 ctatgaagat tttcttccgg tcagcgcagc cggcattttt cagtcgaatt tgggaaatga
     1921 aacgctggcc agaagccacg gcaatgccag ccgcgacgcc tttgaacagg cgctgggatg
     1981 tgctgtacgg gatgaatttt cgttatatca ggaagcggaa gaacgcagta aacgccgttg
     2041 cggtctgctt taaaagcggt aagcttcaca ggctgtgagg atactgtaaa aggaaggcgt
     2101 tatgttgaat ccctccatcc cgctggtggc gacgcgtcac ggtaaaatcg tgggcgtcgt
     2161 acaggaagaa atccatatct ggcgcggtat accttatgcc gcgccgccaa caggggagct
     2221 acgctggcgt gcgccgcagc ctgttacgcc ctggcaggat gtgcgccagg cggattgttt
     2281 ctcctgcgcc agttggcagg atattacctg gtgtcgcgaa ctcggcggcg gcgatccggg
     2341 aaatttttcc gaagactgtc tctatctgaa cgtctgggct cccgccgtgc gtcatgaacc
     2401 gttgccggtc atggtctggc tacacggcgg cggttacacc attggcgcgg ggagtttgcc
     2461 gccctatgac ggtcaagcgc tggcgaagcg cggcgcgatc gtggtgacgg tcaattatcg
     2521 gcttggccat ctgggctttt tcgcgcatcc ggcgctggaa ggcgaagggg cggagtgtat
     2581 tcataatttc gctttactcg atcaaatcgc tgcgctgcgt tgggtgcagg acaatattgc
     2641 cgcatttggc ggcgatacgc agaatgtgac gttatttggc gaatccgccg gcgcccgcag
     2701 cgtgctgtcg ttgatggctt cgccgttggc gaaggggctt tttcataaag cgattattca
     2761 gagtggttat acgctgccgg atacgccccg cgaggtggcg ctaaaaaaag gcgttgcgct
     2821 ggcggaacat cttggtttag cccatgccac tgccgaacag ctacgcgctt taccggcaga
     2881 gacgttttgg ccgctggacg cgccttttaa aattgcgccg acgccgattt ccggcgacgt
     2941 cgtgctgccg catccgatgc tggaaacctt ctttgcggcg aaacagcatc caataccggt
     3001 gatgatcggc tcgaatagcg atgaagccag cgtattggcc gtttttggcg tcgatattgc
     3061 cggtcaaatt caaaaaatgc gccgtgagcg gcgtgttggc ttggggttaa tccggctgct
     3121 ttatcctgga gtgaaaggcg acgaagcgct agggcggcag gtctgtcggg atatggtatt
     3181 taccacgttg ggttatgtcg tcatgcaagc gcagaagcgg atcggcgaac cgtgctggcg
     3241 ttactggttt gattatgtcg ccgaggcgga gcataacacc tacgcgaata gcgcctgtca
     3301 tggcaatgaa ataccgtatg tattcgatac gttaacgcgg gctgagccca catgccatta
     3361 tgtgaatgag aatgacctgg cctttgcctc gcaggtggcg gattactggg tgaatttcgc
     3421 tcgtcatgcc agccgcacgc gcgacgtgct gcacggcccg gttcgctggc ccgccagcat
     3481 tcgggggcga gatcgtctgt tgcggattgg gctgaacaaa cttgccggtt ttaaagtgga
     3541 aaaccgcttt atgcgtgcgc gtctggcgct gtttaaacga gtcatgaaac atcacgttag
     3601 tctggaataa acttttcata acctgaagaa tgctgcgtga ggtttacatc cgattcggtc
     3661 ggttcttatc gacataaaat atttacgctt ttgcacagtt tccaggcgac caacaattgg
     3721 attattaatg aattttgtct agagtgagcg gtcagaaacg ggcacattct tgctgctgaa
     3781 aaaaccagcg cgggaccatt cacaagacca gaaggactca ttttcaggta tgaatcgtag
     3841 acgatttatt aaaggttcaa tggcaatggc cgccgtgtgc ggttccagcg gtattgcttc
     3901 actcttttct caggcggcgt ttgccgcgga atccgatatt gcggatggta aaattgtccg
     3961 ttttgatttt gctggtctgc aatcaatggc ccaggcgtta gcgaaaaagc cctggggtgg
     4021 cgcgccggga cccttgccgg atacgctcgc caatctgacg ccgcaggcct ataacagcat
     4081 tcagtatgac gcggcgcatt cactctggaa cggtgttgcc aaccggcagc tcgatattca
     4141 gtttttccac gtagggatgg gcttccgtcg tcgcgtacgc atgttttccg ttgatacgac
     4201 gacgcatctt gctcgcgaga ttcattttcg cccggaactg tttaaataca acgatgccgg
     4261 cgttgatacg acgcaactgg aagggcagag cgatctcggt ttcgccggtt tccgtgtctt
     4321 taaagcgccg gaactggcgc ggcgcgatgt cgtctccttc ctgggcgcca gttatttccg
     4381 ggcggtagat gatacttatc agtatggcct gtcggctcgc gggctggcga tagataccta
     4441 tactgacggt caggaagagt tccctgactt caccgcattc tggtttgaca ccgcgaagcc
     4501 gggcgatact acgtttaccg tttacgctct gctggacagc gccagcgtga cgggcgcgta
     4561 taagtttgtg atccattgcg aaaaaacgca ggtgatcatg gatgtagaaa accatctcta
     4621 cgcccgtaaa gatataaagc aacttggcat tgcgccgatg accagtatgt ttagctgtgg
     4681 gaataatgaa cgccgggtat gcgacaccat tcatccgcaa attcacgatt ccgatcggct
     4741 ggcgatgtgg cggggtaacg gcgagtggat ttgccgcccg ctgaataatc ctcagaaatt
     4801 acagttcaac gcatatatgg acgataaccc aaaagggttc ggcctgctgc aactcgatcg
     4861 cgatttctcg cattatcagg atgtcatggg ctggtacaac aaacgtccga gcctgtgggt
     4921 ggagccgcgc agtaagtggg ggaaaggcgc ggttagcctg atggagatcc caaccactgg
     4981 cgaaactctg gataatgtgg tctgtttctg gcagccggaa aaagcgatca aagccgggga
     5041 tacgctggcg tttaattatc gtttgtactg gagcgcgcag ccgccggtac aatcgccgct
     5101 tgcgcgggtc atggcgaccc gtacagggat gggcggcttt cccgaaggct gggcgccggg
     5161 cgaacattac ccggataaat gggcacgccg ttttgctatt gattttgtcg gcggcgatct
     5221 gaaagcggcc gcgccaaaag gcattgagcc ggtaattacg ctctccagcg gtgaggcgaa
     5281 gcaggttgag atcctctacg tagagccttt cgacggttat cgtatccagt ttgactggta
     5341 tccgacctcg gattctacgg caccggtgga tatgcgtatg ttcctgcgct gccaggggga
     5401 ggctatcagc gaaacctggc tgtatcagta tttcccgccc gcgccggata agcgccgtta
     5461 tgtcgacgat cgtatcatgc gttagtcagt ttgccttctg taccgccaca aaggcggtac
     5521 aggttgcgga aattgccatg acataaaccc attcgtgagc cgctgttttt gtgacacggc
     5581 cttttcatcg ttctattttt gcaacagtcc ttcctgttta tccctctcga tcctgcggac
     5641 aggggacatt aagatagctt caccttattt aagatataaa gtgaatataa tgaaaaagag
     5701 ttttcttggt gctctcctgt ctctgggttt attaagtgct gctcatgcag atgtatataa
     5761 atttgataat acgcatacca atgcggtatt taatatcgat cgtttccaga cctcaaccaa
     5821 tcatggcggg ttttatgcta ttagcggcga actgaaatat cagccggaaa agcaagtcgc
     5881 agagatgcgt gtgacgattc ccgtgagcgc cttaaatacc ggggtggatg cgtttgataa
     5941 ccatattcgc agtagcgata ttttggatgc ggaaaaatat ccagaaatag tatttaaatc
     6001 gacaaaatgg cattttgaag ataataaacc agtttctatt gacggtttgt taacaatgaa
     6061 gggagtaact aagcccgtca ccttaaccac caccaagttt ggctgttata tgagcccgat
     6121 attcaaggcg caggtttgcg gtggtgattt tgtcacgcaa atagatcgca cccagtgggg
     6181 tgtagattat ctggtcgata tggggatgac gaaagttgtc gatataaaaa tccaggcaga
     6241 agcggttaag caataaaagg aataatgatg aaaactcatc acctcattcg ggtagtggcc
     6301 tcgctggcaa tgttggcaac atcaggcctg gcttatgctg aagagtacaa agccagcacg
     6361 gacgaaaaag caataaaaat gacgaacgta gcctctctgg aagcgcgcgt tcaggccaga
     6421 atggagaaag gggcatttgg ttatattcgc ggtggagccg aagatgagaa taaccttcgc
     6481 agcaacaccg aaagctttga caaaaaatat attatgccgc gcgtattaca gggcattgag
     6541 ttaaaagaga tcgatttatc aacgcagcta ctgggtattc cgcttaaaac gcctataatc
     6601 caggcaccga tggcggcgca gggcctggcc cacgcctccg gagagttggc gacggcgaaa
     6661 ggcatggcgc aggtcggttc gattttctcg ttgagcactt atggcaacaa gaccatcgaa
     6721 gaggtggcta acgtttccgg gaaaaacccg ttcttcttcc agctttatat gagtaagaat
     6781 aatcaattta acgaatttat tcttgcacaa gcggtaaaac atggcgctaa agcgattatt
     6841 ctgaccgtag attcacctgt cggcggttat cgggaagaag atattaaaaa taacttccag
     6901 ttcccgctga gttttgcaaa cctggaaatg ttcgccagga aaaatgacga tggttcaaaa
     6961 accggcaaag gggcagggat aagtgaaatt tacgcgcagg ctaaacaagc ctttacgccg
     7021 gaggatattg cctatgtaca tcgtatttcc ggtctgccgg ttattgtaaa aggcattcag
     7081 tcgccggagg atgctgaaat tgctatccag gctggggccg caggaatatg ggtttctaat
     7141 catggtggcc gtcaattaga cagcgggccg tcctcattcg atatgcttcc tgcgattgca
     7201 aaagtcgtca acaagcgagt gcctgttatt tttgacagtg gagtacgccg tggttcgcac
     7261 gtattcaagg cgttagccag cggggcggat attgtggcgg ttggccgacc tgtattatac
     7321 ggtcttaatc ttggcggcgc tcagggtgtg gcatcagtga ttgaacagct aaacaaagag
     7381 ctgacaatta acatgatgtt gggtggcgcc aggaatattg aacaagtgaa aacgacacgc
     7441 ttgttaactg aaaaagatct gccacagtaa tacagtaata tagaggtcgg gtattatacc
     7501 cgaccttttc ctgtgtgatt ttcctcgaca acgctttcgg tagaaaatga cgcgctctgt
     7561 ttcctcaaat cctaacgcca ggtgaacttt ctgtgaaatt gtattttccg gcgaggtatc
     7621 ggaagccatt tcccgacacc ctttattcgt tccccatcgt tgcactgctg ctatcaattg
     7681 tttcgctaag ccgcgttgac ggaacgaggg gagaacaaaa ataccttcaa ggaaaaccac
     7741 gggcgaactg tcacagccat tgacataatc gtggcggatt gaggcatccg caaagccaat
     7801 cgccaccccg tctgccatcg caataaatga tgccagatgt tcggcttgca gaatttcttc
     7861 gccgtccgcc agatgggcgt catccgggtg accaggccag agctgttttc gcaatccgcg
     7921 ccagtgctcc agatgggttt tgttcatttg cctgatgtcc attaacgcgc tcctgatgag
     7981 gggtctgaca tgatgagacg gcatcccgcc tgctgataac gtcgggcgat agcagacggg
     8041 agcgcactgt cgctaagaat ggtagtaata caggacagcg tcgccaccgc atggggttct
     8101 acagtatcaa actttgaatg atcggccatc aatatgacct cgcgtgagcg ctgaataatg
     8161 cgcgttttga cgcctacttc aaacatggta gcgttggtga tgcccgtttc aatcgacagc
     8221 gcatcgcaag agataaaggc gcgttcaacg gcaaaggcgt taatcatctc cagcgccaga
     8281 ctctcgccca ccgaaaagta gccggggcga atcagtccgc caataatgta gctctctacg
     8341 tgtgggaagc cacccagttc gttagcgatt ttgatgtcat tgcaaatgac ttttactttg
     8401 gcgtcgacca gacattttgc cagttccaga caggtggagc cagagtcgag aaaaaagcag
     8461 tctccatcct tgatgaacgt gcgggcgagg gcggcaattt cgcgtttcgc ctcgctttgt
     8521 aacgtccgct taacgtcgaa aacatattct ttatcttccg tactgtcgtc aaagtcaata
     8581 caaccatggc cgcgaaccat accgggataa cggctggcga tatagtgaaa atcccggcgc
     8641 acggttgcct ctgcatagcc aaaaagctca atagcttgtt gtgttgagag gtgcctgtgt
     8701 tgccaaaggt aatgcaacat ctgtttgata cggtcggggc gctgttggct catcagcata
     8761 tgactccttt atagcgcggt gaattgtgac aatgtcacat catagttcgc cgtcgtgaac
     8821 aacgcccggc caatcaccag atgctgggcg cctgcggcgg caagcagccg tgcggcgcga
     8881 agtgtaatac cgccgtccgc ccagcattcc gcagcaggga aatgctctct gctctggctc
     8941 actttttcac acatcgcggc aataaattgt tgcccgcgcc cgtcgggttc gctggtcatg
     9001 atcatcagcg catccagttg caatgccaga taacgataag gcaatagcgg tgttgccggg
     9061 ttaagcgcca gtcctgcttt cgccccgata gcgcgaatat ccgccagaat ctccgagggg
     9121 ttttgcacgc tttcggcatg aatgaaaatc cagccggggc ggatagctgc aagccagggt
     9181 aaccagcgtt gcggtgatga aaccatcagg tgaaatgaga gcggatggcg agagtattgc
     9241 gcgaccgcct gaatggtttt cataccgaag gtaatattgt tgatgaaact ggtatcttcg
     9301 atatccagat gcagcgagcc gagaggcgca tcgtgtaaag cggtcaacgc ctcggcatag
     9361 cgcagcggat cggcggaggc cagtgaaggg tgcaggatca tcggaacctt catcagcgca
     9421 atgcggttaa ttgcgcgaaa agcgcggcat catttggcgc atcttgcaac atcgcgacgc
     9481 tttccggcga gtcgagccac tggctgatgc gttgaatggt gcgaatatgt gcttcggcat
     9541 ccgtggcgct ggcgcaaagc aacagccaga tgggatcgca atccgcattg ccgaaagcga
     9601 ccggcgttga tagcgtagtg acgctgattt gattatggtt ggcgccttgc tctggtctgg
     9661 catggggcag cgcaatcccc ggcgcgataa gataatatgg cccccattta agggtgttct
     9721 caataatacc gtccaggtag cagggggccg ccgcgccgaa ggtaatcagc ggacgaacgg
     9781 cgatatccag cgcgtgtcgc cagtcgctgg catggcgttg cgcctgaacc cacttaacat
     9841 cattaatcat cgatcgttga ctccttgccg gttcgggtta ctctgaaacc gatccccggc
     9901 gtgtcttttg gcgaaggcga cggagatcgg cagaagagtt atcgctctct gcaggggata
     9961 agcgttttgc ttatccccat tttattgtcg gatatggcgt actttctcca taaacttcgc
    10021 cacgcgcgcc tggtcgacaa agttggcgaa gacgccgtct tttttaaacg tggttgccgt
    10081 tacgcatccg tcggcaatgc agagctgctc ctcgacgttt tccagacaca ccccggtatt
    10141 cgccagcacg accgtgtcgg gaacggtatc ttttacccgc ttcagtatgg cgctatccgt
    10201 gcgggcgccc gccgtcagcc ccgagacgca cagggcatcg gggttattgt taaatacggt
    10261 cgatttcgca attgaacaga catctcggtt tcccagatac accgccgctt ccggcacgat
    10321 gttaaacagc gttttcacgt ggcctgcgcc gatgcgatgc tgatggcgaa tagtttcgcc
    10381 gacattcgta tcccagacgc caaaatcgct ggcgtaagca ccggtgaaaa tttcgcgaat
    10441 aaattttgcg tcggtcgcca tcgccaaatc aaaagaggcc acagggtccc acaacacgtt
    10501 taccccaaac ggtacgcgaa tttcactcat taactgaccg atgattcgtg ccatcgcggc
    10561 agtcgtttcc ggtctgactt tcgttaaata aggcagacta aattcgttgg agaacatcac
    10621 cgcatccacg ccgccatttt gtagcgccat taaatcgtca tgggcgcggt caattaccca
    10681 gttcatgcct ttcctggtat cgaacccggg atcgcccggc agcgcccgta aatggcacat
    10741 ggcgataacg gctttttctg ttcctattac ctcttttagc caactcattc tgggttgctc
    10801 cttattccgg tagttcacgt ttacgtaaga caagtatgat gctggcgaca atgccgacca
    10861 caataaccac accaatcatg cccagcgaca tcaattcaga tattgaccag ccaaacatat
    10921 ttcccaccga cagcgcggta atttgcgcgt tttcagcggc gaagctaaag ccgcctttga
    10981 gcgccatatc ggtaaagtac ggcgcgaact gggtggcgat cagcaaaacg gtaatcatga
    11041 caatgatgcc gctgagcaga gtacgaatca gatcgccgcg atgaataact gtggccatgc
    11101 agataaaaaa tggcgcgacc ggtaaatcag ccagcggcag gactttattg cccggcagta
    11161 tgctcgccag aattaacatg atgggaatta acagcagtcc aaccgcgatg gtggtcgggt
    11221 ggcctaacgt cactgcggta tccagaccga taaagacttc gcgcccttta aagtgtttct
    11281 ggaagaactt acgcgcgccg tcggaaatgg gcattaatcc ctcaacgata aggcgaatca
    11341 tgcgcggaaa cagcaccata atcgccgcca cggtaatcat taaggttgcg caccctttaa
    11401 agccttcgcc tgcagcaagt ccgaagatca gcccgagaac aacgccaatg atcaccgggt
    11461 cgccgaccat cccataccgt ttttggatct cctgagcgtc aatattgcgt cctttcataa
    11521 acggtatttt ttcgtatatc gcatccagca atacgaacaa cggcacggag ctggagccat
    11581 acccttgcgg aatagaaatc ccttccagac ccacaatgtt ctgtacccgt ttcgtcgtcc
    11641 agtcggccat tttcaacgac aaggcggcat ggcaaatcgc gcccagtacg ccataaatca
    11701 gactgccggt catcaactgg acgaccgttc cggtaatggc gtagtgccag tagttataaa
    11761 tatcaacgtt catggttttg gtcagacgag tcaccagcat accgacgttg agcagaaaga
    11821 taacgggaat gatcatcgcg ccgatggccg tcgcatagcc gacgccggat gcgggcccgg
    11881 cgccgacgtc aaacacatgc agcgtcaggc caaaacgctc aatcatcact ttaatcggcg
    11941 gactgagact gtcgatcgcc atgacgatca ccagccccat gccgacaaaa ccgatgccga
    12001 ccgtcacccc cgctttcacc gcctgcagcc agggaatacg aaagattaag ccgatgataa
    12061 tcataatgat gggcacaaag acggtgccgc cgagagacag gatgtaatca aacataatgc
    12121 cccctttatt gtgttaacag cgccttgatt tcttgtttta atgcgtcgtc gttgatgcct
    12181 gtcagcaggg cggcgccgtt gagcgtcggg atgccatagt cactgtgcgt acgcatggac
    12241 gttacgatga gatccatacc gttacagttc aacgggatct cattcagaca acattgcgcc
    12301 gtggttgccg caatgccttg ctccgcaaga aagtcctgca gtttttgtgc aatcatggtt
    12361 gatgtcgaca tgccggtacc acatgccaca aggatctttt tcatcatggt cgtgcctctt
    12421 gtgtagcgcc tgtttcaggg tcaatgggaa actgttctgg cgacatattg gccagcgcag
    12481 tcagtaaacg gatacaatca gccaggtcgc gcaggctggc gacttcggct ggcgagtggg
    12541 tatagcggca gggaatagaa agactggcgc agggaatacc gtccagttca acctgaatgt
    12601 agcctgtttc ggtgatgacg cctggcgcga cttcacgctg tacgggaata ttattttcgt
    12661 gcgcggtggt ctccagcatc cgcagcaaac gcggcggcgt aatcagtccc gccaacgtac
    12721 cgcgtccgtg atagttcaga caggtgatgc cgacgccgtg gttgacccgc acatccgagt
    12781 aatcctgcag gtcaggcgtg tcgcaggagg gggtgatatc aataccaatc gccaggtcgg
    12841 ggcgcacgcg tcgtaaaacg ggaacaatcc cgcgaatatt gaactcttcc tgtaccgacg
    12901 cgaccaggaa taccgcgata tcaagcggtg tggaggcgag ggcctcggcg acgcccagta
    12961 gcgccgtaca ccccagcctg tcatccagcg ccttactgca caccaggtcg ttgcccagac
    13021 agtgcggcgg gttgtaaagg gttactggcg tccccacctg aatacccatt cgttcggcat
    13081 ccgctttatc ttttgcgccg atatcaatcc agagtttatc gagcgcgggt ggctgggtgc
    13141 gctcgtcacc cttcgcgaag tgatatgctt taataccgat acagcccatg atatcgcctg
    13201 aacatccggc aagcgtcaca atcgaaccgg gcatagtaat ttgcgccggg ccgcccacgc
    13261 gttcaaaacg taaaaaaccg gagggttcga tcttgcgtac cataaaaccc acttcatcca
    13321 tatgcgcaaa aatcatcagg cgaagcgcgt cggatttatc gctgccataa cgggcgacga
    13381 cattacctaa gcgatcccgc cagacgtctt tggcctgctg ttcgaacgcg tgctgcataa
    13441 cgtttgcaat actgctttca tgtcctgaaa tcccgtttag ccgcagtaaa gaaaaaagcg
    13501 tttcctgcac agaaaaggtc attggcgtct ccgtggtgat aaaacaatca gtcgttgagc
    13561 gttttatagg cggagaatgg ttggataagt gtgaaatgtg tcacgcggaa atacgctaaa
    13621 tatggtcaat aaaaaataat gtgatggcga tacaataaaa acgctcatat cacctgcggg
    13681 ttatcggtaa accaggctat ttatgtgatc acgaccaaca acgaagaagg gcaacgcgat
    13741 ggtggaaatt attcctgtta gcacgacgct ggaactgcga gcggcagatg aaagtcatgt
    13801 tccggcgctg caccaactgg tactcaaaaa caaagcgtgg ctacaacagt cgctcgactg
    13861 gccgcaatat gtcacgtcgc aggaggaaac gcgtaagcat gtgcagggta atatgctgtt
    13921 gcaccagcgt ggttacgcca aaatgtacct gattttctgc caggatgaga tggcgggcgt
    13981 actctcattt aatgccatcg agccgataaa caaagccgcc tatatcggtt actggctgga
    14041 tgagtccctt caggggcaag ggataatgtc gcaatcatta caggcgctga tgacacatta
    14101 tgcccggcgc ggcgatattc ggcgcttcgt cattaaatgc cgcgttgata atcaggccag
    14161 taacgcggtc gcacggcgca accattttac gctggaaggc tgtatgaaac aggcggagta
    14221 tcttaacggc gactatcacg acgttaatat gtatgcccgc attattgatg cggattaaag
    14281 agaaccgact aagggggtac gcgtaatacg atcttctcca ttgatcactt ttgggccgcg
    14341 taggtgaata gcattgccgt caaacgctat caccgccgcc cgtccgctaa tctcgacctg
    14401 gcgctcaatc agaatttcgc cctgtataca ggcatggcct tcaatcagca cgcggtcgtc
    14461 cagtaaaatc ggacctccgc gtacctcagc atgtccgcct accagcacat gatgttttaa
    14521 cacacagttg ccttcgatta acgcatgttc cgctacctgc gagctgtagc gaagggtagg
    14581 gatagcatct tcctctgtgc cggcgataac ccgcgcatgg ccatagactt tggcgcagtc
    14641 acagatccag acattattgt ctttgttgcc ttcgatgagc gcgaaatcaa agacctccgc
    14701 ccggtgctca ataaaagcgt gagtgatagt ggcgtcgcca taaagctgta cctgatggac
    14761 aatccgcgaa tggttcacgg tggcgcgatc gtaaatttgt aaaatctgcg catgttcatg
    14821 cgttagtccc tgaacagcga gaatttctga ctggtttaac acgcgggcat cgccataaat
    14881 cgcacactct ccacgcacgg aagaggactg aatggtgacg ttgtcactta tccgtgcgcc
    14941 atcgctgata tcagcgcgat caatccagac gttatcgcct attcgcacgt tattgtagag
    15001 cgtgcacggc tgcgtgatac gcgcgttacc cgtaatttcc gtgcccgcaa aggccatcgc
    15061 gttttcatca taaatccagc aatccccctg ttgtgacagc acattatcgg catcaaccca
    15121 gccgccggag gttccggctt taacatcgtt aaaatccgtt acggcaataa cttgtcgtaa
    15181 taagacgctt ttcttctcac cgtctacctg ataagtaaaa gcacgaggtt cttcactcag
    15241 tcgatatttg atcataggga aattccgtgt gaacgattaa gataaccgta gcaaaggtac
//
LOCUS       DAJVKX010000108        15253 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.108, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000108 DAJVKX010000000
VERSION     DAJVKX010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15253
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.108"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            29..544
                     /locus_tag="OPY25_003351"
     CDS             29..544
                     /locus_tag="OPY25_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA helicase"
                     /protein_id="HCS0928881.1"
                     /translation="MEPAMNSIFYSVIILLLLTGAILFLMWEVNKKRPGGKTVNLNQT
                     EPMTKEEGEDHFSVLMNSITPVWYWRVNHEYIDFLHATIKRMTMTELNETPGLFDAQR
                     RCSDLNSAVYKYYDNIKKRCLNGEKVPYSDLDVLNLRQCFREFSLEAYPALVALVWPE
                     YQRPQVKPDEI"
     gene            615..1109
                     /locus_tag="OPY25_003352"
     CDS             615..1109
                     /locus_tag="OPY25_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HCS0928882.1"
                     /translation="MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPN
                     VFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDARNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            1416..3059
                     /locus_tag="OPY25_003353"
                     /pseudo
     CDS             1416..3059
                     /locus_tag="OPY25_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
     gene            3144..3431
                     /locus_tag="OPY25_003354"
     CDS             3144..3431
                     /locus_tag="OPY25_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HCS0928883.1"
                     /translation="MNNHFGKGLMAGLHAPYAYSAHHAVNFCSEYKRGFVLGFTHRMF
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENHSGMAVRFFMAGYRLEG"
     gene            3621..4739
                     /gene="hybO"
                     /locus_tag="OPY25_003355"
     CDS             3621..4739
                     /gene="hybO"
                     /locus_tag="OPY25_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HCS0928884.1"
                     /translation="MTGDNTLITSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVS
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAADGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGTPPKLDAKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHRQGWCLYHLGCKGPETWGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLAHVENQTPRSEKPDVNMKEGGNISA
                     GAVGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            4742..5728
                     /gene="hybA"
                     /locus_tag="OPY25_003356"
     CDS             4742..5728
                     /gene="hybA"
                     /locus_tag="OPY25_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HCS0928885.1"
                     /translation="MNRRDFIKAASGGALLLGAAPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPARNPEGEQTWSNNDKLSPYTNNIIQVWRSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKTDDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYEDLDLPK
                     LDDLSTGARSEHVQHTLYKGMILPLAALAGLTVLVRRNSKNDHHDGGDDHES"
     gene            5718..6896
                     /gene="hybB"
                     /locus_tag="OPY25_003357"
     CDS             5718..6896
                     /gene="hybB"
                     /locus_tag="OPY25_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HCS0928886.1"
                     /translation="MSHDPKPLGGKIISKPVIIFGPLIVLCMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLKRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSVLTAF
                     IMGFSIVIFEGALVQAGLKGNGPDEKNLFVKLTNTISVLLAIFVVLRFGELIYRDKLS
                     YAFAGDFYSAMFWIEVVLMVFPLVVLRVAKLRNDSRMLYLSALSALLGCATWRLTYSL
                     VAFNPGGGYHYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            6893..8596
                     /gene="hybC"
                     /locus_tag="OPY25_003358"
     CDS             6893..8596
                     /gene="hybC"
                     /locus_tag="OPY25_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HCS0928887.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHAISSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALKADPEKASAMLDGVSSWHLNSAQEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMQLPPEVNLIAVAHYLQALECQRDANRVVALLGGKSPHIQNL
                     AVGGVANPINLDSIGTLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAYYPEWLERG
                     KGAVNYLSAPEFPTDGKNGSFLFPGGYITNADLSTYRPITSHSDEFLIKGIQESAKHA
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLCKLAAGRE
                     STQTKLNEIIALYQKLTGKTLEMAQLHSTLGRIIGRTVHCCELQNVLQDQYNALIVNI
                     GKGDYTTFVKPNIQATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPIADPAKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            8596..9090
                     /locus_tag="OPY25_003359"
     CDS             8596..9090
                     /locus_tag="OPY25_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HCS0928888.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYTLSDFVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKNAPGTIMVLRDDEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPQSLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPKE
                     TAHV"
     gene            9083..9571
                     /gene="hybE"
                     /locus_tag="OPY25_003360"
     CDS             9083..9571
                     /gene="hybE"
                     /locus_tag="OPY25_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HCS0928889.1"
                     /translation="MSETFSGFDTAPVARVQAAFEEIAHRSMHDLSFLHPTMPVHVSD
                     FTLFEGQWTGTVITPWMLSALIFPGPDQIWPGRTVGEKLGLQLPYGTMTFTVGELEGV
                     SQYLACSLMSPLSRSLSPEEGVRLADDCARMLLSLPVSNPDAPQTSRRALLFGRRSCE
                     NA"
     gene            9564..9905
                     /gene="hypA"
                     /locus_tag="OPY25_003361"
     CDS             9564..9905
                     /gene="hypA"
                     /locus_tag="OPY25_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HCS0928890.1"
                     /translation="MHELSLCQSAVEIIQQQAEQHGVARVTGVWLEIGALSCVEERAV
                     RFSFDIACQGTLAQGCELHIDYRPAQAWCWDCSQVVEILRHDAQCPHCHGDRLRVDTG
                     DSLKVKSIEVE"
     gene            9933..10181
                     /gene="hybG"
                     /locus_tag="OPY25_003362"
     CDS             9933..10181
                     /gene="hybG"
                     /locus_tag="OPY25_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HCS0928891.1"
                     /translation="MCIGVPGQVLAVGDDIHQLAQVEVCGIKRDVNIALICEGKPADL
                     IGQWVLVHVGFAMSIIDEDEAKATLDALRRMEYDITSA"
     gene            10257..11309
                     /locus_tag="OPY25_003363"
     CDS             10257..11309
                     /locus_tag="OPY25_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCS0928892.1"
                     /translation="MNKFLRQLSLLALLFCWPLMSQAARTFTDQLGRQVTVPDTLDRV
                     VVLQHQTLNLLVQMNATDKIVGVMANWKQQLGDGYARLAPELAQKASLGDLTHVDPEK
                     LVALRPQVVFVTNYAPQEMIDKISRLGIPVVAISLRHDVAGEQAKMNPTLADEEQAYN
                     RGLREGITLIGDIVNKPQEAKALIEAMNKGRKMVSDRLQSVPENERVRAYMANPELTT
                     YGSGKYTGLMMAHAGALNVAASSAKGFKQVTMEQVIAWDPQVIFVQNRYPKVVNEILH
                     NPQWQVIDAVKHHRVYLMPDYAKAWGYPMPEAVGIGELWMAKKLYPEKFHDIDMQKAA
                     NDWYQRFYRTDYQGVQ"
     gene            11309..12019
                     /locus_tag="OPY25_003364"
     CDS             11309..12019
                     /locus_tag="OPY25_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCS0928893.1"
                     /translation="MRILAAGSLRVVWPQLMTAFQADAVCDFGPAGLLRERIEAGEAC
                     DFFASANLAHPQALLESGRALRVAPFTTNRLCLSVRAQAMREGEDWLSLLTRRDLRIG
                     TSTAGCDPSGDYTQQLFSRMGKEGEAIRKRAVALVGGRQTLPLPAGRLAAEWLINHDY
                     TDIFIGYASYAPRLRQVNSLRVVDIPEPYNPVAEYGFACLSEQGKTLADFLLSARARL
                     ILMQHGFSEAPHMTHSQN"
     gene            complement(12087..12953)
                     /gene="yghU"
                     /locus_tag="OPY25_003365"
     CDS             complement(12087..12953)
                     /gene="yghU"
                     /locus_tag="OPY25_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HCS0928894.1"
                     /translation="MADNTYQPAKVWTWDKSGSGAFANINRPVSGPTHDKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGEGDQFSSGFVDINPNSKIP
                     ALRDNSYNPPIRVFESGAILVYLADKFGHFLPQDLAKRTETLNWLFWLQGAAPFLGGG
                     FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAHHPYVAGEEYTIADMAIWPWFGN
                     VVLGNVYDAAEFLDAGSYQNVQRWAKQVAERPAVKRGRIVNRTNGPLNERLHERHDAS
                     DFENHTEDKRQS"
     gene            13180..15036
                     /gene="gss"
                     /locus_tag="OPY25_003366"
     CDS             13180..15036
                     /gene="gss"
                     /locus_tag="OPY25_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HCS0928895.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYNSLDPWDDDDAAFR
                     SYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQA
                     FPNGSPRAPEAGALLIWQKGGEFNETGHVAIITQLLDNKIRIAEQNVIHTPLPPGQQW
                     TRELEMVVENGCYTLRDTFDDTTILGWMIQTDDTQYSLSQPDIANQSLAIRGARLPEK
                     GQFDGQWLDERDPLQKAYVQANGHVINQDPYQYFTITESAEQELIKATNELHLMYLHA
                     TDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADS
                     ASCHTEAGLILEKWAEQGYTGKGHNPAEGLINELAGAWKHSKARPFVHIMQDDDIEED
                     YHAQFMQQALHQAGFASKILRGLGELRWDDAGQLIDGDGRLVNCVWKTWAWETAMEQI
                     REVSETEYAAVPIRTGHPENEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLFP
                     HHRYLLDTDFTVNDELVQTGYAVKPIAGRCGSNIDLVSHQEELLDKTSGKFATQKNIY
                     QQLWCLPKVAGKYIQVCTFTVGGNYGGTCLRGDDSLVIKKESDIEPLIVIKA"
BASE COUNT         3486 a         3781 c         4319 g         3667 t
ORIGIN      
        1 acatggtgta attttaaaat caaaaaaaat ggagcctgct atgaacagta ttttttattc
       61 tgttattata ttgctattac tgaccggcgc gatactcttc ctgatgtggg aggttaataa
      121 aaaacgtcct ggtggaaaaa ccgtaaattt aaatcaaact gaacccatga caaaggaaga
      181 gggcgaagat catttctcag tattaatgaa ttcgataacg ccggtatggt actggcgcgt
      241 taaccatgaa tatatcgatt tccttcatgc aacgataaaa cgaatgacaa tgactgagtt
      301 gaatgaaacg cctggattat ttgacgcaca gcgtcgttgc agcgacctta actctgccgt
      361 ttataagtat tacgacaata taaagaagcg ttgtctgaac ggagaaaagg tgccgtattc
      421 ggatttggac gtccttaatt tacgccagtg ttttcgtgag ttcagtcttg aagcctaccc
      481 ggcgttggtc gcgctggtat ggccggaata tcagcgccca caggttaaac cggatgagat
      541 ttaactgaca tgttgatctg atgttgtatg gttgagatat actgttgctg gttttagtta
      601 cctgacaggt ccctatggaa cgctttcttg aaaatgtaat gtatgcgtct cgctggctgc
      661 tcgcgccggt gtattttggc ctctctttgg cgctgatcgc tttagcgcta aaatttttcc
      721 aggaaattct acacgttctg ccgaacgttt ttgccctagc ggaggccgat ctgatcctgg
      781 tgctgttatc gctggttgat atgacgctgg tcggcgggtt gctggtaatg gtcatgttct
      841 ccgggtatga aaactttgtc tctcagctgg atatctctgc gggcaaggag aagctgaact
      901 ggctggggaa aatggatgcg acgtcgctaa aaaataaggt ggcggcatcg atagttgcta
      961 tctcttccat tcacctgtta cgcgtgttta tggatgcgag aaacgtcccg gataacaaat
     1021 taatgtggta tgtcatcatc catctgacct ttgtcctgtc ggcgttcgtg atgggctatc
     1081 tggacagatt gacgcgacat aaccattgag ccgccgtcca cggcggggca gtcgggcaaa
     1141 ggacgctgag cccggctgta aaacagcgct tctttaacgg tggataaccg tctccctgca
     1201 gccttacgca atatttttac tacatctatt catttactca gtaataacac tgaaagattt
     1261 tctctgcgtt cacagatata taacatctac gggtacgtaa acggcgataa ctgtaaaaaa
     1321 atggagaatg cattatatat tctccgcgcc ttgccgataa cgagagtgcg tcatcgtctg
     1381 atgactaatc tcttatattc agcaaggaaa ttcatatgcg tttgctgcaa aactttacta
     1441 ttcgtatggt catgctgacg atactgggac ttttttgtct actctggtcg ggggtgggtt
     1501 tatacagcgt ccatgcttta tccgaagttt cggaaggaaa tgatattgac cggcatcttg
     1561 tgcggcaaat gacggtgcta agccagggta acgatcaata tttccgcttt gttacccgcc
     1621 ttagccgcgc gatggatgta aaaatcggcg gcggcacgcc cgattttgcg cccgcccggc
     1681 agtcgctcga gaatatgcgt cagaagctgg aggagatgaa agcgctatcg ccagggccga
     1741 tgaaccctga tatctcaagg gcggtgttgt ccaactggca ggccttgctg gagaaaggcg
     1801 tcattcctca aatgcaactg gcgcagcaag gatcgctgac cgcctggagc gaacatgcca
     1861 gtacggtcac gcctgcactt agccgcgcgt tcggcgccag cgcggaacgg tttaatcatg
     1921 aagctggcgc catgctggat aacacccgtg tgatggtcga tggtaaaacc tataccatcc
     1981 gcatcctgct tattacggcg gtgattctgg gcattgccat cctgattttt accgatcgct
     2041 atttggttgc aatgatggtg aaaccgctgg agcgcatccg tcagcagttt cagcgtatcg
     2101 cgcaaggcga tcttagccag ccgattgaag cgttggggcg taactgcgta ggccggttgg
     2161 tgccgctact gcgcgcgatg caggacagtt tacgcgaagc cgtcagtacg atccgcgccg
     2221 gaagcgacaa tatctggcgc ggcgcgacgg aaatttctac cggtaataac gatctctctt
     2281 cccgaacgga agaacaggcc gtcgcgctgg aagaaactgc cgccagcatg gaacagctta
     2341 ccgcaacggt aaaaatgaac gccgaacacg ctcgccaggc gagtcagctt gcggatgccg
     2401 cctcgctaac ggcaggaaaa ggcggtgaac tggtttccga tgtggtagaa acaatgaacg
     2461 gtatttccgc cagttcgcag cagatcgccg aaattactac cgtgattaat agtattgctt
     2521 tccagaccaa tattctggcc ttgaacgcag cggtagaagc ggccagagcg ggcgagcagg
     2581 gacgcggctt cgcggtggtc gccggtgagg tacgtaacct ggccagccgc agcgcggggg
     2641 cggcgaaaga aattgaagct ttaattggcg aatcggcacg tcgcgtagcg cagggcgcgc
     2701 agttggtcta ggagaccggc gcgacgatgg acgccatcct gcgcggcgtc acggaagtga
     2761 cgacgattat gaaacagatc gcgtccgcct ccgaagagca gagtaaaggt atctctcagg
     2821 ttggcgtggc gatcacgcaa atggatagcg ttacgcaaca aaacgccgcg ctggttgagc
     2881 aggtttccgc cgcggcggcg gcgctggaac ggcagacgga ggatttgcaa cgctccgtac
     2941 agcagttccg gctttccgct agtgagccgc aacaacgcgt aacgacgaaa gcggcgcctg
     3001 gcgttcagag aatggcgtcg gctcccgcac agtctactga tgaatgggtt gccttctgat
     3061 gtgaagcaaa aaagcgcgta atgcgctggc cttcatttaa ccagttgcta tataatttat
     3121 tatatagcga ctaaggaggt cagatgaata atcattttgg gaaagggtta atggccgggt
     3181 tgcacgcgcc atatgcatat agcgcgcatc atgcggtgaa tttctgttct gagtataaac
     3241 gtggctttgt attgggtttt acacaccgta tgttcgaaaa gaccggcgat cgtcaactta
     3301 gcgcgtggga ggccggaatt ctgacgcgtc gctatggtct ggataaagaa atggtgatgg
     3361 atttctttaa agagaatcat tccgggatgg cggttcgctt ctttatggct ggttatcgac
     3421 tcgaaggttg atccaacagg ggtattatct tgctttaatt aattacacta tcgcctcttc
     3481 ccttcgtttt actgttccgt cgaagtatta tggcgcacat aaccataaaa aaagtgtggt
     3541 aaatggcgta ccgatcgcaa taacttcttc gcgaacagtg caaaataaaa gctaggtctt
     3601 cgtaacggaa taactataaa atgactggag ataatactct catcacttct cacggcatta
     3661 accgtcgtga tttcatgaag ctttgtgcag cactggccgc tactatgggg ctcagtagca
     3721 aagccgccgc agaaatggca gaatcggtat ccaatccaca gcgtccgccc gttatctgga
     3781 ttggcgctca ggagtgtacc ggttgtaccg aatcactgct tcgtgctaca cacccaaccg
     3841 ttgaaaacct cgttctggag actatctctc tggaatacca cgaggtactt tccgccgcat
     3901 tcggtcacca ggtcgaagaa aacaaacata acgctctgga gaagtataaa gggcaatatg
     3961 ttctggtggt ggatggttct atcccactaa aagataacgg tatctactgc atggttgccg
     4021 gcgagccgat cgtggatcac atccgcaaag ccgccgacgg cgcagccgcg attatcgcta
     4081 tcggttcctg ctcggcatgg ggcggcgttg ctgcggctgg cgtaaaccca accggcgctg
     4141 tcagtctgca ggaagtctta ccgggcaaaa cggttatcaa tattccaggt tgtccgccaa
     4201 acccgcataa cttcctggcg accgtcgcgc atatcatcac ttacggcacg ccgccgaagc
     4261 tggatgcgaa aaatcgtcca acctttgcct atggccgtct gatccatgag cattgcgaac
     4321 gtcgtccaca cttcgacgca ggccgttttg ccaaagaatt tggcgacgaa ggccaccgtc
     4381 agggctggtg cctctaccat cttggctgta aagggccgga aacctggggc aactgttcta
     4441 cattacagtt ctgtgacgtt ggcggcgtct ggccagtggc gatcggtcat ccttgctatg
     4501 gctgtaacga agaaggtatc ggcttccata agggcattca ccagcttgct catgtcgaaa
     4561 accaaactcc gcgttcagag aaacctgacg tcaatatgaa agaaggcggc aatatctctg
     4621 cgggcgctgt cggtctgctt ggcggcgtag tcggtctggt tgccggcgtc agcgtgatgg
     4681 cggtacgtga actggggcgt cagcaaaaga aagataacgc tgactcacgg ggagaataac
     4741 cgtgaacaga cgtgacttta ttaaagcagc ctccggtgga gcattgctgt tgggcgccgc
     4801 gccgtctgtc agccatgcgg ctgcagaaaa ccgtccgcca attccaggtt cgctgggcat
     4861 gctgtatgac tccactctgt gcgtgggctg tcaggcctgc gtcacaaagt gtcaggatat
     4921 caacttcccg gcgcgtaacc cggaagggga gcagacctgg tcgaacaacg acaaactgtc
     4981 gccgtatacc aataacatta tccaggtatg gcgtagcggc acgggcgtga acaaagatca
     5041 ggaagagaac ggctatgcct acatcaagaa acagtgtatg cactgcgtcg atcctaactg
     5101 cgtttccgtt tgtccggtgt cggcgctgaa aaaagatccg aaaaccggca tcgtccacta
     5161 tgacaaagat gtctgcaccg gctgccgtta ctgtatggtc gcctgtccgt acaacgtacc
     5221 taagtacgac tacaacaacc cgtttggcgc gcttcacaag tgtgagttgt gtaaccagaa
     5281 aggcgttgag cgtctggata aaggcggttt gcctgggtgt gtggaagttt gtccggcagg
     5341 ggccgtcatt ttcggtactc gtgaagagct aatggcggaa gcgaaaaaac gtctggccct
     5401 caaaccaggc agtgaatatc actatccgcg ccagacgttg aaaacggacg acacctatct
     5461 gcatacggtg cctaaatact acccacacct ctacggtgaa aaagagggcg gtggtactca
     5521 ggtgctggtg ctgacaggcg ttccttatga agatttggat ctgccgaagc tggatgacct
     5581 ttcaaccgga gcgcgctccg agcatgttca acacacgctt tataaaggca tgatactacc
     5641 cctggctgcg ctggcgggct taaccgtgct ggttcgtcgt aatagcaaaa acgaccatca
     5701 cgatggagga gacgatcatg agtcatgatc caaaaccgct gggcggaaaa atcatcagta
     5761 aaccggtcat tatttttgga ccgttaatcg tcctgtgtat gctccttatc gtgaagcgtc
     5821 tggtcttcgg gttgggctcc gtttccgacc tgaacggcgg tttcccgtgg ggcgtctgga
     5881 ttgcctttga cctgttgatc ggcaccggct ttgcctgcgg cggttgggcg ttggcatggg
     5941 cggtgtatgt ctttaaccgt gggcaatacc atccgttggt gcgcccggca ttgctggcaa
     6001 gcttgtttgg ttactcgctg ggcggcctgt cgatcactat cgacgtcggt cgttactgga
     6061 acctgccgta cttctacatt ccaggtcact tcaacgtgaa ctcggtactg tttgagacgg
     6121 cggtctgtat gaccatctac atcggcgtga tggcgctgga gtttgcgcct gccttgtttg
     6181 aacgtctggg ctggaaagtg tcgctcaagc gtctgaataa ggtgatgttc tttattatcg
     6241 cgctgggcgc gctgctgccg acgatgcacc agtcctcaat ggggtcattg atgatctcgg
     6301 cgggctataa agtgcatccg ctatggcaaa gctatgaaat gctgccgctg ttctcggttc
     6361 tgaccgcgtt tatcatgggc ttctccattg tcatatttga gggggcgctg gttcaggcag
     6421 gcctgaaagg aaacggtccg gatgagaaaa atttgtttgt taagctgacg aataccatca
     6481 gcgtgctgct ggcgattttc gtcgtcctgc gctttggcga actgatttat cgcgacaagc
     6541 tgtcctatgc gtttgccggc gatttttact ccgctatgtt ctggattgaa gtcgtcctga
     6601 tggtcttccc gttagtggtg ctgcgtgtgg cgaaactgcg taatgactct cgtatgctgt
     6661 acctgtcggc gctgagcgcg ctgttgggtt gcgcgacgtg gcgtctgacc tattcgctgg
     6721 tggcattcaa cccgggtggc ggctaccact acttcccaac ctgggaagaa ttgttgattt
     6781 ctattggttt tgtggctatt gagatttgtg catacatcgt actcattcgt ctactgccga
     6841 tacttcctcc tttaaaacaa aacgatcata atcgtcatga ggcgagcaaa gcatgagcca
     6901 gagaattact attgatccgg taacccgtat tgagggtcat ttacgcattg actgcgaaat
     6961 tgagaacggc gtcgtatcca aagcatgggc gtccggcacc atgtggcgcg gtatggaaga
     7021 gatcgtgaag aaccgcgatc cgcgcgatgc gtggatgatt gtgcaacgta tttgcggcgt
     7081 ttgtacgaca actcacgcga tctcctccgt tcgtgcggcg gaaagcgcgc tgaatattga
     7141 tgttcccgtc aacgcgcagt atatccgtaa tattattctg gcggcgcata ccacccatga
     7201 ccacattgtc catttctacc agctctctgc gctggactgg gtggacatta cctctgcgct
     7261 gaaagccgat ccggaaaaag cttctgcgat gctggatggc gtgtcgagct ggcacctgaa
     7321 cagcgcgcaa gagttcacga aagttcagaa caagatcaag gatcttgtcg ctagcggtca
     7381 gttaggtatt ttcgccaatg gctactgggg gcacccggca atgcagttac cgccggaggt
     7441 caacctgatt gcggtcgccc actatctgca ggcgctggaa tgtcagcgtg acgctaaccg
     7501 cgtggtggcg ttgctgggcg gtaaatcgcc gcatatccag aacctggcgg tcggtggggt
     7561 ggcgaacccg atcaatctcg acagcatcgg tacgttgaac cttgaacgcc tgatgtacat
     7621 caaatcgttt atcgataagc tgagcgattt tgtcgagcag gtgtataaag tggataccgc
     7681 agtcatcgcg gcctactatc cggaatggct ggagcgcggc aaaggcgcgg tgaactacct
     7741 gagcgcgccg gaattcccga ccgacggtaa aaacggcagt ttcctgttcc cgggcggtta
     7801 cattaccaat gccgatctgt cgacataccg tccgatcacc tctcactccg atgaattcct
     7861 gattaaaggt attcaggaga gcgcgaagca cgcctggtat aaagatgaag cgccgcaggc
     7921 gccgtgggaa ggcaccacga ttccggctta cgacggttgg tcggatgacg gtaaatactc
     7981 atgggtcaag tcgccgacat tctacggcaa aaccgtcgaa gtcgggccgc tggcgaacat
     8041 gctatgtaaa ctggccgcag gtcgtgaatc cacgcagacc aagctcaatg aaatcattgc
     8101 gctttatcag aagctgaccg gcaaaacgct ggaaatggcg caacttcact ctacgctggg
     8161 tcgtatcatc gggcgtaccg ttcactgttg tgaactgcaa aacgtattgc aggatcaata
     8221 caacgcgctg attgtaaata tcggcaaagg cgattacacc acgtttgtga agccgaacat
     8281 tcaggcgacg ggcgagttca aaggcgtggg cttcctggag gcgccgcgcg gtatgctgtc
     8341 tcactggatg gtgattaaag acggtattat cagtaactat caggcagtgg tgccatcgac
     8401 ctggaactca ggtccgcgta acttcaacga tgacgtgggg ccgtacgaac agtcgctggt
     8461 cggtacgccg atcgccgatc cggcgaagcc gctggaagtg gtacgtacca tccactcctt
     8521 cgacccttgc atggcgtgcg cggtgcacgt ggtggacgcc gatggcaatg aagtggtctc
     8581 ggtgaaggtt ttgtaatgcg gatattagtc ttaggggtcg gcaatatttt gctgaccgat
     8641 gaagccatcg gggtacgtat tgttgaagcg ttagagcaac gatacaccct gtcggatttc
     8701 gttgagattc tggatggcgg tacggcggga atggaacttc ttggcgatat ggcgaatcgg
     8761 gatcatttga tcattgccga cgccatcgtg tcgaaaaaga acgcgccggg aaccattatg
     8821 gtactgcgcg acgatgaagt tccggcgctg ttcaccaaca aaatctcccc ccatcagctt
     8881 ggactggccg acgtattgtc ggccctccgc tttaccggcg agtttccgaa gaagttgacc
     8941 ctggtcggcg ttattccaca gtcgctggaa ccgcacatcg gcttaacgcc aaccgtcgag
     9001 gcgatgattg aacctgcgct tgagcaggtt cttgctgcgc tgcgtgaatc cggcgtcgaa
     9061 gcaattccta aggagacggc gcatgtctga aacgttttcc ggattcgaca cggcgcccgt
     9121 cgcccgggtt caggcggcgt ttgaagagat agcccatcgt tcgatgcacg atctttcgtt
     9181 tctgcatccg actatgcctg tgcatgtctc tgattttacg ttgtttgaag gacaatggac
     9241 gggcacggta attacgccgt ggatgttaag cgcattaatc ttccctggcc cggaccagat
     9301 ctggcccggg cgtaccgtcg gtgaaaaact cggtctgcaa ctgccttatg gcacgatgac
     9361 ctttaccgtt ggcgaactgg aaggcgtttc acaatatctt gcctgctcgt tgatgtcgcc
     9421 gctttcccgt agcctgtcgc cggaagaggg cgtccggctg gcggatgact gcgcgcggat
     9481 gctgttatcc ctgccggtaa gcaatcctga tgcgccgcag acaagccggc gtgcgttgct
     9541 gtttggccgt cggagctgtg agaatgcatg agctgtctct ttgccaaagc gccgttgaaa
     9601 ttattcagca gcaggcagaa cagcacggcg tggcgcgcgt caccggcgta tggctggaga
     9661 taggcgcgct ttcgtgcgtt gaagagcgcg cggttcgttt cagctttgac atcgcctgcc
     9721 aggggacttt agcgcaaggg tgcgaattgc acatcgacta cagaccggcc caggcctggt
     9781 gctgggattg cagtcaggtg gtggaaattc tcaggcatga cgcgcaatgt ccgcattgtc
     9841 atggcgatcg cctgcgggtg gataccggcg attcgttgaa agtaaaaagt attgaggtcg
     9901 aataacccgc attttatttc aggtggttaa ttatgtgtat tggcgtcccc ggtcaggtgc
     9961 tggccgtcgg agatgatatt caccagcttg cgcaggtgga agtgtgtggc atcaaacgtg
    10021 atgtcaatat tgctctgatt tgtgaaggta agccagccga tctgataggg caatgggtat
    10081 tggtacacgt tggttttgcg atgagcatca ttgacgaaga cgaagcgaaa gccacgttag
    10141 atgcgctgcg ccgcatggag tacgacatca ccagcgcgtg atcccttaat cacctctatt
    10201 atatcgctct ataatcgttg tataattatt tatatatcga ttgtggggcg aaacctatga
    10261 ataaattttt gcgccagctc tctctgctgg cgttgctttt ttgctggccg ttaatgtcac
    10321 aggcggcgcg tacttttacc gatcaacttg gccgccaggt cacggttccc gataccctcg
    10381 acagagtggt ggtgctccag catcaaacgc tcaatctcct tgtacagatg aatgccactg
    10441 acaaaatcgt tggggtcatg gcgaactgga aacagcaatt aggcgacggc tatgcgcgtc
    10501 tggcgccgga actggcgcaa aaagcctcgc tgggcgatct aacgcacgtt gatcctgaaa
    10561 aactggtggc gctgcgcccg caggtggtgt ttgtcacgaa ttacgctccg caggagatga
    10621 tcgacaagat cagccgtctt ggcattccgg tggtggcgat ttcgctgcgc catgatgttg
    10681 ctggcgagca ggctaaaatg aacccgaccc tggccgatga agagcaggct tataatcgcg
    10741 ggctgcgtga aggaataacg ctgattggcg atatcgtcaa taaaccgcag gaggcgaaag
    10801 cgctgattga ggcgatgaat aaaggtcgca agatggtcag cgaccgtttg cagtcggttc
    10861 ctgaaaatga gcgagttcgc gcctatatgg cgaatccgga gctgaccacc tacggttccg
    10921 gtaaatacac cggtctgatg atggcccatg cgggggcgct gaatgtagcg gcatcctcgg
    10981 cgaaaggctt taagcaggtg acaatggagc aggtgatcgc ctgggatcca caagtaatct
    11041 ttgtccagaa tcgctatcca aaggtcgtca atgagatcct gcacaatccc cagtggcagg
    11101 tcattgacgc ggtgaagcat catcgggttt acctgatgcc ggattatgcc aaagcctggg
    11161 gatatccgat gccggaggcg gtgggaatcg gcgaactatg gatggcgaaa aaactctatc
    11221 cggaaaaatt ccacgatatt gacatgcaaa aggccgctaa cgactggtat caacgttttt
    11281 accgtactga ctatcagggc gtacagtgat gcgaatactg gctgcgggga gcttgcgcgt
    11341 cgtctggccg cagctaatga cggcgtttca ggcggatgcg gtatgtgatt tcggtccggc
    11401 ggggctgtta cgtgaacgca tcgaagcggg cgaagcatgc gacttttttg cttcggcgaa
    11461 cctggcgcat ccgcaggcgc tgctggaaag cgggcgggca ctgcgggtcg cgccttttac
    11521 gacgaaccgt ttgtgtctga gcgtgcgggc acaggcgatg cgtgaaggcg aggactggct
    11581 gtcgctatta acccggcggg atctgcggat cggcacctca acagcaggtt gcgatccttc
    11641 cggcgattat acgcagcagc ttttttcgcg gatgggcaag gagggcgaag cgatccgaaa
    11701 acgcgcggta gcgctggttg gcggcagaca gactttgccg ttaccggcgg gccggctggc
    11761 ggcggaatgg ctcatcaatc atgattacac cgatatcttt atcggctatg ccagctatgc
    11821 tcccaggcta cggcaggtta attcgctgcg agtggttgat atcccggaac cttataatcc
    11881 cgtggctgaa tatggctttg cctgcctgag cgagcaggga aaaacgcttg ccgacttttt
    11941 actgtcagca cgggcgaggt tgattctcat gcaacatggg tttagtgaag cgccgcatat
    12001 gacgcactcg cagaactgat aagcgaagcg tcagcaggga ataccatgcc ggatgacgac
    12061 attactacct catccggcat tatggtttaa ctttgacgtt tatcttcggt atggttttcg
    12121 aagtcgctgg cgtcatggcg ttcatgaagc cgttcgttca atgggccgtt ggtccggttg
    12181 acaatgcgcc cccgctttac cgccggacgt tcggctacct gtttcgccca gcgttgtacg
    12241 ttttgataac ttccggcatc cagaaactcc gctgcatcat agacattccc cagcaccacg
    12301 ttgccgaacc acggccagat ggccatatcg gcaatagtgt actcttctcc cgcgacatac
    12361 gggtggtgag ctaactgctt atccagcacg tccagcagac gcttggcttc catggtgaag
    12421 cgattaatgg cgtactcaat ttttaccggc gcataatgat agaagtgacc gaaaccgccg
    12481 ccgaggaacg gcgccgcgcc ctgtagccag aacaaccagt taagggtttc tgtgcgctta
    12541 gccagatcct gcggcaggaa atggccaaac ttatccgcca gataaacaag aattgcgccc
    12601 gactcaaaaa cccgaatcgg cgggttgtat gagttatcgc gcagcgccgg aatttttgag
    12661 ttcggattga tgtcaacaaa gccgctggag aactgatcgc cctcgccgat gcgaatcaac
    12721 caggcgtcat attcggcgcc ggtcacgccc agcgccagga gttcttccag cataatggtc
    12781 actttctggc cgttaggcgt ccccagcgaa tagagctgta acggatgttt gccgacgggc
    12841 agcgttttgt cgtgcgtcgg gccggaaacc gggcgattaa tgttagcgaa cgcgccgctg
    12901 ccggatttat cccacgtcca gacttttgcg ggttgataag tattatctgc catattgacc
    12961 tgccttcaca gtggtggtgt tgaagcagtg tagcagcttg ctaaccggac atttaaccga
    13021 ttgggacatt ccgacgagtg aaattttaac cttctggcct cagtgtgcct tattgaggtg
    13081 tatgattatg tcgacctctg tccggttagt gtcacagagc agacaatcag agcgaaatca
    13141 cgccaggctg ctcaggcggt cttgttttga ggtaagtgca tgagcaaagg aaccaccagt
    13201 caggatgccc ccttcgggac attattgggt tacgcccccg gcggcgtagc gatctactct
    13261 tcagattaca attccctcga tccgtgggac gacgacgacg cagcttttcg tagctacatc
    13321 gacgatgaat acatggggca taaatggcag tgcgtggaat ttgcccgccg ttttctcttt
    13381 ctgaattatg gcgttgtttt tactgacgtc ggcatggcct gggaaatttt ctcgctgcgt
    13441 tttctgcgcg aggtcgtgaa tgacaatatt ttgcctttgc aggccttccc gaacggttcg
    13501 ccgcgcgcgc cggaggccgg ggcgttgctc atctggcaaa agggcggcga gtttaacgaa
    13561 accgggcacg tcgcgattat cacccaactc ctggataaca aaattcgcat tgctgagcaa
    13621 aacgttatcc acacgccatt gccgccaggg cagcagtgga ctcgcgaact ggaaatggtc
    13681 gtagaaaacg ggtgttacac cctgcgcgac acctttgatg acacgacgat tttaggctgg
    13741 atgatccaga ccgacgacac gcaatacagt ttgtcacagc ctgacatcgc gaatcagtcg
    13801 ctggcgattc gcggcgcaag gctgccagag aaaggtcagt ttgacggtca gtggctggat
    13861 gagcgcgatc cgttacaaaa agcctatgta caggcgaacg gacacgttat caatcaggac
    13921 ccgtaccagt attttaccat caccgagagc gccgaacagg agcttatcaa agcgaccaat
    13981 gagttgcatt tgatgtacct gcacgccacg gacaaagttt taaaagacga taatctgctg
    14041 gcgctattcg atatccccaa aattctttgg ccgcgcctgc gtctctcctg gcagcgccgt
    14101 cgtcaccata tgatcaccgg tcgtatggat ttctgcatgg atgaacgcgg gctgaaagtc
    14161 tatgaataca atgccgattc cgcatcatgc cataccgaag cgggattaat tctcgaaaaa
    14221 tgggctgagc agggctatac cggtaaaggg cataacccgg cggagggctt aattaacgag
    14281 ctggcaggcg cctggaaaca cagtaaagcg cgtcctttcg tccatatcat gcaggatgat
    14341 gatatcgagg aggactatca cgcgcagttt atgcagcagg cgctgcatca ggccggtttc
    14401 gcgagcaaaa ttctccgcgg gctgggcgag ttgcgctggg atgacgccgg gcagttgatc
    14461 gatggcgacg gacggctggt gaattgtgtc tggaaaacct gggcgtggga aacggcaatg
    14521 gagcagatac gcgaagtcag cgagacggag tatgccgcag tgcctattcg taccgggcac
    14581 ccggaaaatg aagtccggct gattgatgta ttactgcgcc cggaagtgtt ggtgtttgaa
    14641 ccgctgtgga cggtgatccc gggtaacaaa gcgatcctgc ccatcctgtg gtcgctcttc
    14701 ccacatcatc gctatttgct cgacacggat tttaccgtta acgatgagct ggtgcagacc
    14761 ggctatgcgg taaaaccgat tgccggacgt tgcggtagta atattgattt ggtgagccat
    14821 caggaagaac tcctggataa aaccagcggc aagttcgcca cgcagaaaaa tatctatcag
    14881 cagttgtggt gcctgccgaa ggtcgccggg aagtatattc aggtctgtac gtttaccgtg
    14941 ggcggtaact acggcggtac gtgcctgcgc ggcgatgatt cattagtcat taaaaaagag
    15001 agcgatattg aaccgttaat cgtcatcaaa gcgtaacggg gtcattctcg tcgggatatc
    15061 ggcgttggcg ccgatatccc gcctgttgtg tttaccaacg aacggctgtc agcttgccat
    15121 ttactggtaa catatgagaa ataatatcac aaattattct taacttttct aacgcaggcg
    15181 gtgacgctcg ctgcgttggc gcactcgttt cctgattttc gtctaatcgg tactttttgc
    15241 ggctggttac gcc
//
LOCUS       DAJVKX010000109        15249 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.109, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000109 DAJVKX010000000
VERSION     DAJVKX010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15249
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.109"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            125..1312
                     /locus_tag="OPY25_003367"
     CDS             125..1312
                     /locus_tag="OPY25_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 domain-containing protein"
                     /protein_id="HCS0928896.1"
                     /translation="MNNVISSKDNHNHTLVFTGKGGKYFVICLVNFLLTCITFGIYAP
                     WAMVKCRRYIYTNMTLNNQPFAYKATGGALFISVLLVFIIYIVSLSFIEHGHPGLGFT
                     LFGLLIAIIPFMAVKGLQYQAMMTSLNGVHFGFQCSMRRAWWYMFALPVLLMVALYIV
                     LYIISLVTIAVGGLVFNIVFLGLLAIIGIGVINGITYSKWMTLFGNGANFGIHRFSIQ
                     VNVKTCIRGCVLAMLTLFPFAVVIGYLIAPVFTDMILLSMMGNAQAGGALILQYYGQI
                     MACYFLYFLAIIVVTSYLYVALRNLFLNNLSLANDSIRFHSSVTAHGMLWRLLVVFVI
                     SGVTLGLAYPWLKIWLVSWLAQNTQVQGDLDSLELTNDEKPLENSPLMWISRGIMPYF
                     PFI"
     gene            complement(1454..4309)
                     /locus_tag="OPY25_003368"
     CDS             complement(1454..4309)
                     /locus_tag="OPY25_003368"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCS0928897.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESKESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGRDAFIDKIWQWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETVLGDTGVAVNPEDPRYKDLIGKFVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAEVFDTKGEESNVYSSEIPAEFQK
                     LERFAARKAIVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDNDGNVYVGRT
                     EDEVRQENNLGADVQLRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQMAEKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEEQDCGFNGGEMTLSLADRWILAEFN
                     QTVKAYREALDNFRFDIAAGILYEFTWNQFCDWYLELTKPVMTGGSESELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVICGITADTIMLQPFPEYNAAQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSEEAVRRVNDNRSFLLNLARLESITVL
                     PADDKGPVSMTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEIARIEGKLSNEG
                     FVARAPEAVIAKEREKLDGYAEAKAKLIEQQAVISAL"
     gene            complement(4309..4752)
                     /gene="holC"
                     /locus_tag="OPY25_003369"
     CDS             complement(4309..4752)
                     /gene="holC"
                     /locus_tag="OPY25_003369"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HCS0928898.1"
                     /translation="MKNATFYLLDNDTTVNGLSAVEQLVCEIAAERWRAGKRVLIACE
                     DEKQAIRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRNSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEETLKQLARERYKAYRVAGFNLNTATWK"
     gene            complement(4889..6400)
                     /gene="pepA"
                     /locus_tag="OPY25_003370"
     CDS             complement(4889..6400)
                     /gene="pepA"
                     /locus_tag="OPY25_003370"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HCS0928899.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMRELGMNAYLAVGHGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELKLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSDQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE"
     gene            6795..7895
                     /gene="lptF"
                     /locus_tag="OPY25_003371"
     CDS             6795..7895
                     /gene="lptF"
                     /locus_tag="OPY25_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HCS0928900.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MVLALFTGILAAVNVMWAGPWSSKHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFHDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNKGTRFEGTAL
                     LRDFRITDFQNYQAIIGHQAVALDPNDTDQMDMRTLWNTDNDRARAELHWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSIKSNGGKGKLDPVIWMWAV
                     NLIYLALAIGLNLWDTVPVRRLRARFLRKGAV"
     gene            7895..8977
                     /gene="lptG"
                     /locus_tag="OPY25_003372"
     CDS             7895..8977
                     /gene="lptG"
                     /locus_tag="OPY25_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HCS0928901.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GNYDALGAGMYTLLSVPKDIQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELAGISIYAFNDQRRLQSVRYAASAKFDPEHKVWRLSQVDESDLQNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQFNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIVGALLPSASFFLISLWLMLRKS"
     gene            complement(9183..10181)
                     /locus_tag="OPY25_003373"
     CDS             complement(9183..10181)
                     /locus_tag="OPY25_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCS0928902.1"
                     /translation="MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVARETGERIAQIM
                     EEINYIPNRAPAMLLNAQSYTLGVLIPSFQNQLFADILAGIESVTSGHNYQTLIANYN
                     YNRDSEEESVINLLSYNIDGIILSEKYHTLRTVKFLRSATLPIVELMDIQGDRLDMEV
                     GFDNRQAAFDMVSTMLDKRQRRKILYLGSKDDIRDEQRYHGYCDAMTRRGLAPLRINP
                     RAISSIHLGIQLMRDALTAHPDVDGVFCTNDDIAMGALLWCRERQLAVPEQISIAGFH
                     GLEMGRQMIPSLASVITPRFEIGRRAAQMLLNKIKNNDLNHNTIDLGYQIYHGNTL"
     gene            complement(10245..11369)
                     /locus_tag="OPY25_003374"
                     /pseudo
     CDS             complement(10245..11369)
                     /locus_tag="OPY25_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463342.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
     gene            complement(11364..11735)
                     /locus_tag="OPY25_003375"
                     /pseudo
     CDS             complement(11364..11735)
                     /locus_tag="OPY25_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463346.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
     gene            11958..12042
                     /locus_tag="OPY25_003376"
     tRNA            11958..12042
                     /locus_tag="OPY25_003376"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11992..11994,aa:Leu,seq:caa)
     gene            12206..13471
                     /locus_tag="OPY25_003377"
     CDS             12206..13471
                     /locus_tag="OPY25_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HCS0928903.1"
                     /translation="MKLNARQVETAKPKDKTYKMADGGGLYLEVSAKGSKYWRMKYRR
                     PSDKKEDRLAFGVWPTVTLAQARAKRDEAKKLLVQGIDPKTEQKEAQAENSGAYTFET
                     IAREWHASNKRWSEDHRSRVLRYLELYIFPHIGSSDIRQLKTSHLLAPIKKVDASGKH
                     DVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTTKARHYPALPSSRFPEFLARL
                     AAYRGRVMTRIAVELSLLTFVRSSELRFARWDEFDFDKSLWRVPAKREEIKGVRYSYR
                     GMKMKEEHIVPLSRQAMVLLEQLKQISGDKELLFPGDHDATKVMSENTVNSALRAMGY
                     DTKTEVCGHGFRTMARGALGESGLWSDDAIERQLSHSERNNVRAAYIHTSEHLDERRL
                     MVQWWADYLDIIQYEHITPYEYARVCNIK"
     gene            complement(13534..14610)
                     /locus_tag="OPY25_003378"
     CDS             complement(13534..14610)
                     /locus_tag="OPY25_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HCS0928904.1"
                     /translation="MIEVGRIIAERYKILSYVGKGGMQDVYKVLDLKLDLDLALKTPL
                     PGLESKRFLKSAKIAAKINHHNIAKTFDYVEDNGNIFLAEEFVEGENLEEKLRHFDFL
                     DPHYGACILHNLAKGIMASHKADVIHRDLKPSNVMVSGGVQISNLKITDFGIATLTQE
                     LFDEAAASGDLTRSTSGTIKGALPFMSPELMFGKKGKPIEASTDIWPLGAMMFKLLTG
                     DYPFGVYLDAAVNVKTKNRMEWPTFMTANPQYQSLSQDLQKIVDKCLSYDSDKRPTAE
                     TLVKACETLCYLSEERHVGRVNNLIQGGISGFIDGTPSNSFFSMESVYGSRYPNTSTR
                     NTVCYSTFDGHPWPRAHPVILWKD"
     gene            complement(14607..>15249)
                     /locus_tag="OPY25_003379"
     CDS             complement(14607..>15249)
                     /locus_tag="OPY25_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014913955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HCS0928905.1"
                     /translation="NKIVKILDFGLARTSGTEAFTHSVIGTLGYMAPELWKRKNISFD
                     QKIDVYAYGVLVLDLFGIEKPDELYEHPPAAITNIPELGKILPKDLARTFISCLSHDK
                     YARPAMSSVRDQIAKYLLKDRHRALFVLNGKKYEINAKNKSVTITWGTSGSMEIVYDG
                     FDFKVGNFSGSATINNQQVITNKVFPSCSVITLINEKSRSFVTFDISRPEVIS"
BASE COUNT         3519 a         3818 c         3943 g         3969 t
ORIGIN      
        1 gatcctgaat cagacaaaat aaaaggcgga aaaattaaac aaaaatagta tcgtagtcaa
       61 atcagtaaca atttactggt ttttattatt aattctaata gattgtaatt cagggatatg
      121 attcatgaat aacgttatca gtagtaaaga taaccataat cacacgttgg tgtttacagg
      181 caagggcgga aagtattttg ttatttgcct tgtgaatttc ttgttgacgt gtatcacgtt
      241 tggaatctat gcgccgtggg cgatggtgaa atgtcgacgt tatatttata ctaatatgac
      301 gctaaacaat cagccttttg cttacaaagc cacgggcggc gcattattta ttagtgtgtt
      361 gttagttttt attatttata ttgttagcct ctcttttatt gaacacggtc atcccggtct
      421 cggttttacg ctattcggct tattaattgc gattattcct tttatggcgg tgaaaggatt
      481 acagtatcag gcgatgatga cttcgcttaa tggcgtacat tttggattcc agtgttccat
      541 gcggcgcgcc tggtggtaca tgttcgctct tccggtactc ctgatggtgg cgctttatat
      601 tgttctttat attatctcac tggtaaccat cgccgtcggc ggtttagtgt tcaatatcgt
      661 ttttctcggt ttgctggcta ttattgggat aggggtcatt aacggtatta cctacagcaa
      721 atggatgacc ttgtttggca atggcgcaaa ctttggcatt catcgtttct cgattcaggt
      781 taatgttaaa acgtgcatca gagggtgcgt gttggcaatg ttgacccttt ttccttttgc
      841 tgtcgtgatt ggttatctaa tcgcgccggt gttcaccgac atgattcttt tgagtatgat
      901 ggggaatgcg caggcaggag gggcgcttat tctgcaatat tatggccaga taatggcatg
      961 ttatttcctc tattttctcg cgattattgt ggtaaccagt tacttatatg tggcgttacg
     1021 caacctgttt ttaaacaatt tgtcactggc gaacgattcg attcgttttc attcctctgt
     1081 cactgcacac ggtatgctgt ggcggttact ggtagtgttt gtgatttccg gcgtgacctt
     1141 agggctggct tatccgtggt tgaaaatttg gctggtgagc tggctggcgc agaatacaca
     1201 ggtccagggc gatctggatt cgcttgagtt aaccaatgat gagaagccgc tggaaaacag
     1261 cccgctaatg tggatttctc gtggcatcat gccttacttc ccgtttatct gatgtaaaaa
     1321 ggccgacgtt tacgtcggcc cataattcat gttgtcggat ggtggcgtga atgccttatc
     1381 cggcctaccg atcgcgccat gtcaataagc gaacgtgtag gcctggtaag cgaagcgcca
     1441 tcaggctttc agattacagc gcgctaataa ccgcctgctg ctcaatcagc ttcgctttgg
     1501 cttctgcata accgtccagc ttctcacgct ctttggcgat caccgcttcc ggcgcgcggg
     1561 caacgaaacc ttcgttggac agtttgcctt cgatacgggc aatctcgcct tcgattttcg
     1621 ccacttcttt cgccagacgc gccagctcat cttctttgtt gatgaggccc gccatcggga
     1681 ttagcagttc ggcaccgtcg atgattttgg tcatggaaac cggacctttg tcatcggctg
     1741 gcagcacggt gatgctttcc agacgcgcca ggttcagcag gaagctacgg ttgtcgttaa
     1801 cacgacgaac ggcttcttca ctacagccgc gcagcagcag ttccagcggt ttgcccgggg
     1861 cgatgttcat ttccgcacga atgttacgta cggcaacgat cgcctgcttc agccactcgg
     1921 tatcggccaa cgcggcttca tccacctgcg cggcgttata ttccgggaac ggctgcagca
     1981 taatggtatc ggcggtaatg ccacagataa ccttcacgcg ctgccagatg gtttcggtga
     2041 tgaacggaat gatcgggtgc gccagacgca gcaaaccttc cagcacggtg accagcgtat
     2101 ggcgggtgcc acgcagttca gactcggaac ccccggtcat taccggtttg gtcagctcca
     2161 gataccagtc gcagaactgg ttccaggtga actcgtacag gatgcctgcg gcgatatcga
     2221 agcggaagtt atccagtgct tcgcggtagg ctttaacggt ctggttgaat tccgccagga
     2281 tccagcggtc cgccagcgac agggtcattt cgccgccgtt gaagccgcaa tcctgctctt
     2341 cagtgttcat cagcacaaag cggctggcgt tccacagctt gttacagaag ttacggtagc
     2401 cttccagacg cttcatatcc cagttgatgt cgcggccggt cgaggctagc gccgccaggg
     2461 taaagcgcag ggcgtcggtg ccgtgcggct cgatgccgtt cgggaactgc ttctcggtac
     2521 gcttgcggat tttctccgcc atctgcggct gcatcatgtt gccggtgcgt ttctccagca
     2581 gttccggcag ggagatgccg tccaccatat ccagcgggtc gataacgtta cccttggatt
     2641 tggacatctt ctggccttcg tcgtcgcgaa tcagaccggt catgtagaca gtatggaacg
     2701 gcacctgcgg cttgccgttt tcatctttga tgaagtgcat ggtcatcatg atcatgcggg
     2761 caatccagaa gaagatgata tcgaagccgg acaccatcac gctggtggga tggaactgac
     2821 gcagggcgtc ggtgttttct ggccagccga gggtggagaa ggtccacagc gcggaggaga
     2881 accaggtatc aagaacgtct tcgtcctgac gaagctgaac gtcggcaccg aggttatttt
     2941 cctgacgcac ttcgtcttcg gtacggccaa cgtagacgtt gccgtcgttg tcataccatg
     3001 ccgggatacg gtgaccccac cacagctgac gagagataca ccagtcctga atatcgcgca
     3061 tccaggagaa gtacatgttt tcgtactgct tcggcacgaa ctgaatgtcg ccgttttcaa
     3121 ccgcttccac cgccggtttc gccagcacgt ctgcacggac gtaccactgg tcggtcagca
     3181 tcggttcgat aactacgccg ccacggtcgc cgtaagggac ggtcagatcg tgcggtttaa
     3241 tttcttccag caggcccagc gcgtcaacgg cagcaacgat ggccttacgg gcagcaaagc
     3301 gttccagctt ctggaactca gccggaatct cgctggaata aacgttagac tcttcacctt
     3361 tggtatcgaa cacttccgcg ctttcgcgaa tgtcgccatc aaaggtcagg atgttgatca
     3421 tcggcagggc gtgacgtttc ccgacttcat agtcgttaaa gtcgtgcgcc ggggtgatct
     3481 tcacgcagcc ggtacctttt tccatatcgg cgtgttcgtc gcccacaatc ggaatgcggc
     3541 ggttaaccag cggcagaata acgaatttgc caataagatc cttataacgc ggatcttccg
     3601 ggttcacggc cacgccggta tcgcccagta cggtttccgg acgggtggtg gcgacgacca
     3661 ggtaatcttt accgtctgcg gttttcgcgc cgtcggccag cggatagcgg atgtgccaca
     3721 tcgagccttt ggactcgcgg ttttccactt ccaggtcaga gatggcggtg cgcagcttcg
     3781 gatcccagtt caccaggcgt ttgccacggt aaatcaggtc ttctttgtac aggcggacaa
     3841 agacttcttt cacggcattg gaaaggcctt cgtccatggt gaagcgctcg cgctcccagt
     3901 caacggagtt gccgagacgg cgcatctgac gggtaatggt gccgccggat tccgctttcc
     3961 actgccagat tttgtcgata aacgcatcgc ggccgtagtc gtgacgggtt ttaccttctt
     4021 cagcggcaat cttgcgctca accaccatct gggttgcgat cccggcgtgg tcggtgccga
     4081 cctgccacag ggtgttttta ccctgcatac gctggtaacg gatcatggta tccatgatgg
     4141 tttgctggaa agcatgtccc atatgcaaac tgccggtgac gttcggcggc gggatcatga
     4201 tgcagaagga ctctttgctt tcgtcgccgt taggcttgaa atagccctgc ttttcccagt
     4261 gctcgtaaag cggctgttcg atatcttggg ggttatatgt cttttccatt atttccaggt
     4321 tgccgtattc aggttaaaac cagccacgcg gtaggctttg tagcgttcgc gcgccagttg
     4381 tttcaaagtt tcttcgtaag ggacgaagtc taccacttct gtgaaagcgg tggcaaaatc
     4441 tgcaaagctt gtacgcaggc tgattaaaat atcgcgcggg ctgctgttgc gtttttgcgg
     4501 ccaggcgatt tcaaccggcg cgccgccgcg tgggccttcg cctgccagat tgtgcgggac
     4561 aaaactttcc gccggtcttg cccacagcgc ttcatccagc cgaatggcct gcttctcatc
     4621 ttcgcaggcg atcagcacgc gcttgccagc gcgccaacgt tctgcggcaa tttcacacac
     4681 cagttgttca acggcgctta aaccgttgac ggtggtgtca ttgtccagaa gatagaacgt
     4741 cgcattcttc atatatgagg cttcttgtgg tggatttaaa tgcgttgcca tgatgcaccc
     4801 cgtaggccgg ataagcgtgg cgccatccgg caaaacgcct gatggtggcg ctaatgcgcc
     4861 ttatcaggcc tacggggtaa tctcaaactt actcttcgcc gttaaagccc gcacgattga
     4921 gcaggaactg cgacagcagc gctaccggac gaccggtggc acctttggct ttaccggaac
     4981 gccaggcggt accggcgata tccaggtgcg cccagttgta cttacgggta aagcgcgaca
     5041 ggaagcagcc cgcggtgata gcgccgccag gacgaccacc aatgttcgcc atatccgcaa
     5101 agttggactc cagttgttcc tggaactcat cgcccagcgg cagacgccac gcgcggtcgc
     5161 ccgcttgctc ggacgcgccg atcagttcat gcgccagcgg gttatggttc gacatcagac
     5221 cggtaatgtg atggcccagc gcaatcacgc aggcgccggt tagcgtcgcg acgtcaatga
     5281 ccgcttccgg ttcgaagcgc tcaacgtagg tcagcacgtc gcacaaaacc agacggcctt
     5341 cggcgtcggt gttcaggact tcaacggttt gatcagacat agtggtcagc acgtcgccag
     5401 ggcgataagc gcgtccgccc ggcatgtttt cacagcccgc cagtacgccg ataacgttaa
     5461 tcggaagctt aagctcggcg accatacgca tcacgccgta aaccgccgcc gcgccgcaca
     5521 tgtcgtactt catctcgtcc atcccttcag atggcttgat ggagatgccg ccggagtcga
     5581 aggtcaggcc tttacctacc agcacgatcg ggcgcgcgtc ttcggacgga ttgcccttgt
     5641 actcaatcac cgacatcagc gattcattct gcgaaccgtg gccgaccgcc agataagcgt
     5701 tcatacccag ttcgcgcatt tgctgttcgc cgatcacgcg ggtgatgaca tttttgctgt
     5761 agctgtcggc caactggcgc gcctgtgacg ccaggtaggc ggcgttacag atattgggcg
     5821 gcatgttgcc gagatctttc gcagccttaa tcccggcggc gatggccaga ccgtgctgaa
     5881 tggcgcgttc gccgctggtg agctcacggc gggtcggcac attaaagacc atcttacgta
     5941 gcgggcggcg cggctcgctc ttgttggtct tgagttgatc aaagctataa agcgtctctt
     6001 tggccgtttc gacggcctga cgcactttcc agtagttgtt gcggccttta acgtgcagtt
     6061 cggtcaggaa acagacggct tccatcgaac cagtatcatt cagagtattt atcgttttct
     6121 gaataacctg cttatactga cgttcatcaa gctcgcgctc tttgccgcaa ccaatgagga
     6181 ggattcgctc ggaaagaacg ttaggaacat ggtgcagcaa cagagtctgc cccggttttc
     6241 cttccagttc gccgcgacgc agcaatgcgc tgatgtatcc gtcgctaatt ttgtcgagct
     6301 gttctgcaat cggagaaagg cgacgcggtt caaagacgcc cacgacaatg caggcactcc
     6361 gctgtttctc cgggctaccg ctttttacac tgaactccat gcactatgct cctgaatctt
     6421 aaagacaaca gtggtggcta cagctatact cgtcgtcttt caagttgcag atgcgttggc
     6481 tgcgcctgct cacccctgtc gcttacctga tgtaagctcc ggggctccac agtcctgccg
     6541 cctgcctgca actcgaaatc cattagagta tagaaattga aagctttcgt aactcatatc
     6601 cgctgttgcg gtgacttcgt gttaatctta acgttattac ggcattggca cgtcagaaca
     6661 agttctgaga ggtgaatccg ctgagtataa tgatcttagc gatgatttcg acgactcaag
     6721 agaataaatg acgtttaagc catgaaacaa gctaaattcc agcaaaaaaa tggtttttta
     6781 cgggcgtatt taaagtgata atcataagat atctggtgcg ggagacgctc aaaagccagc
     6841 tggcgatact cttcatctta cttttgatct tcttttgtca aaagttagtg aggattctcg
     6901 gcgcggcggt tgacggcgat attcccgcaa atctggtgct ctcgcttctg gggctgggcg
     6961 taccggaaat ggcgcagctc atcctgcctt taagcctgtt cctggggctg ctgatgacgc
     7021 tgggcaaact gtataccgaa agtgaaatta cggtcatgca cgcctgtggg ttgagcaaag
     7081 ccgtgctggt aaaggccgcc atggtactgg cgttatttac cggtatcctt gcggcggtta
     7141 acgtgatgtg ggccggcccc tggtcgtcaa aacaccagga tgaagtgctg gcggaggcga
     7201 aagcgaaccc cggtatggcg gcgttggcgc aggggcaatt ccagcaggcg accaacggca
     7261 gctcggtgct gtttatcgaa agcgttgacg gcagcgactt ccacgatgtt ttcctggcgc
     7321 aaattcgtcc taagggcaat gctcgtcctt ctgtggtagt ggccgattcc ggacacctta
     7381 ctcagttgcg cgatggttcc caggttgtca ccttaaacaa agggacgcgt tttgaaggga
     7441 cggcgttgct acgcgatttt cgcatcaccg acttccagaa ctatcaggcg attattggtc
     7501 atcaggccgt ggcgctggac ccgaacgata ccgaccagat ggacatgcgc acgctgtgga
     7561 ataccgacaa cgatcgcgct cgcgccgagc tgcactggcg tatcacgtta gtctttaccg
     7621 tatttatgat ggcgctgatg gtcgtgccgc tcagcgtggt gaatccacgt caggggcgcg
     7681 tcttgtctat gttgcccgct atgctgcttt atctgctgtt cttcctgatc cagacctcca
     7741 ttaaatcgaa tggcggtaaa ggcaaactgg acccggttat ctggatgtgg gcggtcaacc
     7801 tgatctatct ggcgttggcg attggtttaa acctgtggga tacggtgccg gttcgccgcc
     7861 tgcgtgcccg ttttctgcgt aaaggagcgg tataatgcag ccatttggtg tgcttgaccg
     7921 ctatatcggt aaaaccattt ttaccaccat catgatgacg ttgttcatgc tggtgtcgct
     7981 ctccgggatc atcaagtttg tcgatcagct gaaaaaagcg gggcagggta actacgacgc
     8041 gctgggcgcg ggtatgtaca ccctgctcag cgtacctaag gatatccaga tcttctttcc
     8101 tatggcggcg ctgcttggcg cgctgctggg gctggggatg ctggcgcagc gtagcgaact
     8161 ggtggtgatg caggcatcgg gtttcacccg tatgcaggtg gcgctgtcgg tgatgaaaac
     8221 ggctatcccc ctggtgctgt taaccatggc gatcggcgaa tgggtcgccc cgcagggcga
     8281 gcagatggcg cgtaactatc gtgcgcaggc gatgtatggc ggctcgctgc tttccaccca
     8341 gcaaggtctg tgggcgaaag acgggaataa ctttgtctat attgaacggg tgaagggcga
     8401 cgaggagctg gccggcatta gtatttacgc tttcaacgat cagcgtcgtt tgcagtcggt
     8461 gcgttacgcc gcttcggcaa aattcgaccc ggagcataag gtctggcgtt tgtcgcaggt
     8521 ggatgagtcc gatctgcaaa acccgaaaca gatcaccggt tcgcagacgg tgagcggcac
     8581 ctggaaaacg aatctgacgc cggataagtt aggcgtggtg gcgctggacc cggatgcgct
     8641 ttccatcagc ggtctgcata actacgttaa atatctgaag tcgagcggac aggacgctgg
     8701 acgttatcag ttcaatatgt ggagtaaaat cttccagccg ctctccgtgg cggtgatgat
     8761 gctgatggcg ctgtcgttta ttttcgggcc gctacgtagt gtgccgatgg gcgtgcgtgt
     8821 ggtgacgggg attagcttcg gcttcgtctt ttacgtcctc gaccagattt ttggcccgct
     8881 gacgctggta tacggcattc cgccgattgt cggcgctctg ctgccgagcg cgtctttctt
     8941 cctgattagc ctgtggctaa tgctgcgtaa gtcgtaatca cagtaatcgt aggcctgatg
     9001 gcgctgtgct tttcaggcct actccggacc cgtaggccgg ataaggcgtt agcgccgcca
     9061 tccggcagac agcttggtat tcctcgaatg atgtagcgcg taacctgacg cgtggcgctt
     9121 ttggctacgc gttaagcaca ggcaagctgc gggaaagagc ataagcgcag tagttcaaaa
     9181 agttataatg tgttgccgtg ataaatctga taacccaaat caatcgtatt atggttgaga
     9241 tcgttatttt taattttgtt gagcaacatc tgcgcggctc tgcgcccgat ctcaaaacga
     9301 ggggtaatta cgctggcgag gctcggtatc atttgcctgc ccatctccag accgtggaag
     9361 ccggcgatgg agatctgctc cggtacggcc agttgacgct cgcggcacca cagtagagcg
     9421 cccattgcga tatcgtcatt tgtacaaaag acgccatcca cgtccgggtg cgcagtaagc
     9481 gcatcacgca ttagctgtat ccccagatgg atagaggaga tagcgcgggg attgatgcgc
     9541 aacggcgcca gcccccggcg cgtcatcgca tcgcagtagc cgtgataacg ctgctcatca
     9601 cggatatcgt cttttgaacc cagatagaga attttccgcc gctggcgttt atccagcatg
     9661 gtgctgacca tatcaaaggc ggcctgacgg ttatcaaacc ccacctccat atctaagcga
     9721 tcgccctgga tatccatgag ttctacaatc ggaagggtag ctgagcgcag gaatttgacg
     9781 gttctgaggg tatgatattt ttctgaaaga ataatgccgt cgatattgta agacagtaaa
     9841 ttgataacgg actcttcttc cgaatcgcga ttgtaattgt aattcgcaat gagagtttgg
     9901 tagttatgac ccgacgttac ggattcaatc ccggcgagaa tgtcggcaaa caactgattc
     9961 tgaaaagagg ggatcagcac gcccagagtg taactttgcg cgtttaacag catagcaggc
    10021 gcgcgatttg gtatgtagtt aatttcctcc atgatctgcg caatacgctc gccggtttcc
    10081 ctggcgactt ttttcggcga gcggatgtaa cggctcaccg tcatttttgt cacgccagca
    10141 agcgtagcga tatcctgcaa agaaattctg tgattcctca tgttttctcc agtaccgggg
    10201 gcgggaacgt cgcccccatg gttaattggg ctgcggatga tgaattaatg cagaaccgca
    10261 ttcagcgcca gtacgcccag caaccccatg acagaaatca atgtttccat aacggtccag
    10321 gtgcgtaggg tttccccgac gctaagatta aaataccctt taaacagcca aaaaccggga
    10381 tcgttaacat gtgatgcaat aacgcttccc gcgcctgtcg ccagtaccat taacgccgga
    10441 tcggcgtggg ttacgttaat aatcggcaat acgacgcccg ctgtggttat cgcggccacg
    10501 gtcgcggaac ctaacgcaat acgcagcacg gcggctaccg tccagcacat taataacgga
    10561 gatagcgagg tgccggtcat taattgcgag atatattgac ccacgccgct atccaccagc
    10621 acttgcttaa acgcgccgcc gcccgcgatg ataaaaacaa tcatcgcaat agcgccaatg
    10681 gactcgccga cgatatccat cacctgctca accgtacgtc cattgcgtcg ccccagcgta
    10741 aaaatggcga tgataatggc aataaacaac gccactgctg gattaccgat aaattcgaag
    10801 aaaacccgca cggcattcgt ttttggcagc gtgatttcac ataccgctgc gatggccatc
    10861 agaatgaccg ggatcacggc ggcaaaaata ctgttccaga atgacggcat ctcctcttca
    10921 ctgaatagat gaggattaaa taatccttca ggcggcgctt tttcaaatcg cgccagcaat
    10981 tttgaaaaca gagggccggc aacaatcacg gtcggtatgg taatgattaa cccatacagc
    11041 agggtcgtac cgagatttgc ctcaaaaatt gtcgcaatag cggtagggcc gggatgcggc
    11101 ggcaggaagc agtgcgtaac ggataaggcg gcgaccattg gaaccccgac atacagcaat
    11161 ggcagtcccg atgaggccac aattgtaaaa acgagcggca acagcagtac gaatccgact
    11221 tcaaaaaaca ttgccaggcc gacgataagc ccggtgatca ccagcgccca ttgcacgcgt
    11281 tttttgccga acgtattaat gagcgtcgtc gcaatgcgct gcgcggcgcc ggtatcggaa
    11341 attaatcttc ccagcatcgc gccaaaaccg ccacgattga ggatagtggg cactgcccct
    11401 tccaggcagt taatttgatt gccgctgata caggcatcgc agtgtccgca gctgcgcgcc
    11461 gtccagccga ttccaacgcg ctggccgact tttagtccct tatcctgtgc cgcgctaccg
    11521 agtgcggcca cccgaccgat gacctcgtgt ccggcaacca gagggtattg agagaacccc
    11581 cattcattgt cgatcatcga cagatcggaa tggcagatcc cgcagtagtc gacccgtacc
    11641 tcgacatctt ccggttggag ttctcccgcg tcatattcat agagttcgag ctcgccgccc
    11701 gcctctttgg cggcgtagct ttttattatc gtcattgtgc ttcccttaat gtggtgttga
    11761 actgaaaagt gtagagcatg gaggcaaggg acgcccggcg ttaatctgct ggagaaggcg
    11821 ggaagtagcc tgattattct atttaatcct caacgctgct gaaattttca gcacttagcg
    11881 atacaggtgt atgctcgtgc ttgcatggcg gcgtatgaca ggtataatcc acaacgtttt
    11941 ccgcatacct cttcagtgcc gaagtggcga aatcggtaga cgcagttgat tcaaaatcaa
    12001 ccgtagaaat acgtgccggt tcgagtccgg ccttcggcac cattagtact tccaagacca
    12061 tccgagaaag tccaattatc ccttaaaaat caatgattga agcgattttt acgtcctgag
    12121 tcgtctgagg ttgtccgttg aaatccggaa gtcattgggg gcataattgg gggcatctta
    12181 acttcgatta gaaatgtgcc cccaaatgaa gctcaacgcc agacaggtcg agaccgcaaa
    12241 gccaaaagac aaaacctaca aaatggccga tggcggcggt ttgtaccttg aggtttcggc
    12301 caagggatcc aaatactggc gcatgaaata cagacgcccc tctgacaaaa aagaggatcg
    12361 cctcgctttt ggtgtttggc ctactgtgac acttgctcag gcaagagcaa agcgcgatga
    12421 agccaaaaag ttgctagtgc agggcattga tccaaaaacc gaacagaaag aggctcaggc
    12481 cgagaactcg ggggcgtata ctttcgaaac tatcgctcgt gaatggcatg ccagtaacaa
    12541 gcgctggagc gaagaccatc gatcgcgcgt tcttcgctat cttgaacttt atattttccc
    12601 tcatatcggt tcgtccgaca ttcgccagct caaaaccagt cacctgttag ccccgatcaa
    12661 aaaagttgat gccagtggta aacacgacgt cgctcagcgc ctgcaacagc gcgtcacggc
    12721 tattatgcgt tatgccgtac agaacgatta catcgactct aatccagcca gtgacatggc
    12781 cggtgcgtta tcgactacca aagcacgaca ctatccagcc ttaccttcta gccgtttccc
    12841 tgagtttctt gctcgccttg ctgcatatcg tggccgtgta atgacacgga ttgctgtcga
    12901 gctttcctta ctaacttttg tacgttccag cgagttacgt ttcgcgcgtt gggacgagtt
    12961 cgacttcgat aaatcccttt ggcgcgtacc ggcaaaacga gaagaaatta agggtgtgcg
    13021 ttattcgtac cgtggcatga agatgaaaga ggagcatatc gttcctctca gtcggcaggc
    13081 gatggttttg ttagagcagc tcaagcagat tagtggtgat aaagagctgt tgtttccggg
    13141 ggatcacgac gcaactaagg ttatgagcga aaacacggta aatagcgcat tgcgtgcgat
    13201 gggttatgac acaaaaaccg aggtctgcgg gcatgggttt cggacgatgg cgcgtggtgc
    13261 tttgggtgag tcaggattat ggagcgatga cgcgatagag cgtcagttaa gccattctga
    13321 gcgtaacaat gtgcgtgctg cctatattca cacttcagag catttggatg agcgtcgttt
    13381 gatggtgcag tggtgggctg attatctcga tattattcag tatgagcata ttacacctta
    13441 tgaatatgca agagtctgca acataaaatg aatgatattt atagatgata atttaatgga
    13501 ttaaaatagg cacaattact tgtgcctatt aattcaatct ttccaaagaa ttacagggtg
    13561 tgctctaggc catgggtgtc catcaaaagt ggaataacaa acagtatttc ttgttgaggt
    13621 gtttgggtac ctcgaaccgt atacactttc catactaaaa aaggagttag aaggtgtccc
    13681 atcaataaat ccacttatcc ctccttgaat aagattattg acgcgaccga catgacgttc
    13741 ttcggataaa taacaaaggg tttcacatgc cttaacaagc gtttcagctg taggcctctt
    13801 gtccgagtca taacttaagc acttatctac aattttttgt agatcttgtg ataaactttg
    13861 atattgtgga ttggcagtca taaaggttgg ccattccatt ctattttttg ttttaacatt
    13921 aacagcagca tctaaataaa cgccaaatgg atagtctcct gttaataatt taaacatcat
    13981 tgcacctaat ggccaaatat cagttgatgc ttctataggt ttaccctttt taccaaacat
    14041 taattcagga gacatgaagg gtaaagcacc ttttatcgta ccagaggtcg atcttgttag
    14101 gtcaccactg gcagcagctt catcaaaaag ttcttgtgtt agcgtagcta ttccaaaatc
    14161 tgtaattttt agattcgaaa tttgtactcc gccagacacc attacattac tcggttttaa
    14221 atctctatga ataacatctg ctttatgaga tgccattatt cctttagcaa ggttatgtag
    14281 tatacaagcg ccataatgtg ggtctaaaaa atcaaagtgg cgcaattttt cctcaaggtt
    14341 ttcaccttca acaaattctt ccgctaaaaa tatattgcca ttatcttcaa cataatcaaa
    14401 ggtttttgct atattgtgat ggtttatttt tgcagcgatt ttggcacttt taagaaatct
    14461 tttgctttcc aaaccaggaa gtggagtctt taaagctaaa tctaaatcca gctttagatc
    14521 taaaacttta tatacgtctt gcatcccacc tttaccaaca taagataaaa tcttatagcg
    14581 ttctgcaatg attcttccga cttcaatcat gatattacct ccggtctaga tatatcaaag
    14641 gtgacaaagc ttctagattt ttcatttata agagtaatta cactgcagct aggaaatact
    14701 ttatttgtta tcacttgttg gttattaatt gtcgcacttc ctgaaaaatt acctacttta
    14761 aagtcgaaac catcatatac tatttccata cttccactag taccccaagt gatcgtaaca
    14821 cttttatttt tagcatttat ttcatatttc tttccattca ggacgaagag ggcacggtgt
    14881 ctatctttta ataggtattt agctatttga tctctaaccg aagacattgc cggtcgagca
    14941 tatttgtcat ggcttaagca actaatgaaa gttctggcta agtcctttgg aagtatcttt
    15001 cctaattcag gtatattggt tatcgcggcc gggggatgtt cgtataattc atctggtttt
    15061 tctatgccga ataaatctaa aacgaggaca ccatatgcat aaacatcaat tttttgatcg
    15121 aaactaatgt tttttctctt ccatagttca ggagccatat atcctaaggt tccaataaca
    15181 gaatgagtga atgcttctgt gcctgaggtc cttgctaaac caaaatctaa tattttaaca
    15241 attttattc
//
LOCUS       DAJVKX010000110        15238 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.110, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000110 DAJVKX010000000
VERSION     DAJVKX010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15238
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.110"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            346..801
                     /gene="csgB"
                     /locus_tag="OPY25_003380"
     CDS             346..801
                     /gene="csgB"
                     /locus_tag="OPY25_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HCS0928906.1"
                     /translation="MKNKLLFMMLTILGAPGIATATNYDLARSEYNFAVNELSKSSFN
                     QAAIIGQVGTDNSARVRQEGSKLLSVISQEGENNRAKVDQAGNYNFAYIEQTGNANDA
                     SISQSAYGNSAAIIQKGSGNKANITQYGTQKTAVVVQKQSHMAIRVTQR"
     gene            843..1298
                     /gene="csgA"
                     /locus_tag="OPY25_003381"
     CDS             843..1298
                     /gene="csgA"
                     /locus_tag="OPY25_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HCS0928907.1"
                     /translation="MKLLKVAAFAAIVVSGSALAGVVPQWGGGGNHNGGGNSSGPDST
                     LSIYQYGSANAALALQSDARKSETTITQSGYGNGADVGQGADNSTIELTQNGFRNNAT
                     IDQWNAKNSDITVGQYGGNNAALVNQTASDSSVMVRQVGFGNNATANQY"
     gene            1360..1686
                     /gene="csgC"
                     /locus_tag="OPY25_003382"
     CDS             1360..1686
                     /gene="csgC"
                     /locus_tag="OPY25_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HCS0928908.1"
                     /translation="MHTLLLLAALSNQITFTTTQQGDIYTVIPQVTLNEPCVCLVQIL
                     SVRDGVGGQSHTQQKQTLSLPANQPIELSRLSVNISSEDSVKIIVTVSDGQSLHLSQQ
                     WPPSAQ"
     gene            1818..2138
                     /locus_tag="OPY25_003383"
     CDS             1818..2138
                     /locus_tag="OPY25_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HCS0928909.1"
                     /translation="MSVIKKNIPAIGLCICAFFIHSAVGQQTVQGGVIHFRGAIVEPL
                     CDISTHAENIDLTCLREGKKQMHRIDLRQASGLPQDIQSIATVRLHYLDAQKSLAVMN
                     IEYR"
     gene            2226..2765
                     /gene="ymdB"
                     /locus_tag="OPY25_003384"
     CDS             2226..2765
                     /gene="ymdB"
                     /locus_tag="OPY25_003384"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HCS0928910.1"
                     /translation="MTSRLQVIQGDITQLSVDAIVNAANASLMGGGGVDGAIHRAAGP
                     ALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYR
                     NCLLLAEANHFRSIAFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYD
                     EETARLYARLLTQQGDDPA"
     gene            2701..4188
                     /locus_tag="OPY25_003385"
     CDS             2701..4188
                     /locus_tag="OPY25_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HCS0928911.1"
                     /translation="MMKKLPGFTQDYLLSKATTLPDKTRLERAVEPLCARHPGECGIL
                     ALDNSLDAFAARYRLTEMAARTLDVQYYIWEDDMSGRLLFSVLLSAAKRGVHVRLLLD
                     DNNTPGLDDTLRLLDSHPNIEVRLFNPFSFRTLRALGYLTDFARLNRRMHNKSYTADG
                     VVTLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVNDVANDFERYWRCSSVSTLQQVL
                     SLSEQELTQRIELPESWYNDEITRRYLHKLETSQFMADLDRGTLPLIWAKTRLLSDDP
                     SKGEGKAQRHSLLPQRLFDVMGSPTERIDIISAYFVPTRAGVAQLLNLVRKGVKIAIL
                     TNSLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREHETAVHDRGLTGNSGSSLHA
                     KTFSIDGSKVFIGSLNFDPRSTLLNTEMGFVIESETLATLIHKRFTQSQRDAAWQLRL
                     DRWGRINWIDRQQEEEKVLKKEPATRFWQRVLVRLAAILPVEWLL"
     gene            complement(4205..5359)
                     /gene="mdoC"
                     /locus_tag="OPY25_003386"
     CDS             complement(4205..5359)
                     /gene="mdoC"
                     /locus_tag="OPY25_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HCS0928912.1"
                     /translation="MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSAAP
                     SWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKHWWKVRVERVGIPMLTAIPLL
                     TLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWF
                     QKRQETSKPRPAAISLAKLSLIFFLLGVAYAAIRRIIFIVYPAILSDGMFNFIVMQTL
                     FYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETES
                     VITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     SSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG"
     gene            5631..7166
                     /gene="mdoG"
                     /locus_tag="OPY25_003387"
     CDS             5631..7166
                     /gene="mdoG"
                     /locus_tag="OPY25_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HCS0928913.1"
                     /translation="MMKMRWLGAAIMLTLYASSSWAFSIDDVAKQAQSLAGKGYEAPK
                     SNLPSVFRDMKYADYQQIQFNSDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATT
                     VKRIKYSPDYFNFGNVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFREFWIERPKPTDKRLTVYALLDSPRATGAY
                     RFVIIPGRDTVVDVQSKVYLRDKVGKLGVAPLTSMFLFGPNQPSPTTNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSYAMENPQGFGLLQRGREFSRFEDLDDRYDLRPS
                     AWITPKGDWGKGKVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTLTFSRDED
                     KLHAPDNAWVLQTRRSTGDVKQSNLIRQPDGTIAFVVDFVGADMKKLPPDTPVAAQTS
                     IGDNGEIVDSNVRYNPVTKGWRLMLRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            7159..9702
                     /gene="mdoH"
                     /locus_tag="OPY25_003388"
     CDS             7159..9702
                     /gene="mdoH"
                     /locus_tag="OPY25_003388"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HCS0928914.1"
                     /translation="MNKTTEYIDALLLSEREKAALPKTDIRAVHQALDAEHRTYSRED
                     DSPQGSVKARLEHAWPDSLAKGQLIKDDEGRDQLQAMPKATRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYVSRLTKEEQASEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDIWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHQTALIMPICNEDVSRVFAGLRATWESVKATGNAA
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVQGEGQIFYRRRRRRMKRKSGNIDDFCRR
                     WGNQYSYMVVLDADSVMSGECLSGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSIMLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTPWGEAFMRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRSTVGLRTKRWKLFLIPEEYSPPQVLVDTDKYLEMNRR
                     RILDDGFMHAVFNPSLNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHYRVWNAPERYSSWVNHYQSLVLNPQALQGRTSSAG"
     gene            9776..10003
                     /locus_tag="OPY25_003389"
     CDS             9776..10003
                     /locus_tag="OPY25_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HCS0928915.1"
                     /translation="MRIFAVSIMVITLSGCGSIISRTIPGQGHGNQYYPGVQWDMRDS
                     AWRYITILDLPFSLIFDTLLLPLDIHHGPYE"
     gene            complement(10004..10378)
                     /locus_tag="OPY25_003390"
     CDS             complement(10004..10378)
                     /locus_tag="OPY25_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secY/secA suppressor protein"
                     /protein_id="HCS0928916.1"
                     /translation="MTMYATLEEAIDAAREEFLADHPGLEQDEANVQQFNVQKYVLQD
                     GDIMWQVEFFADEGEDGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRTAADEWDER"
     gene            complement(10460..11674)
                     /gene="mdtG"
                     /locus_tag="OPY25_003391"
     CDS             complement(10460..11674)
                     /gene="mdtG"
                     /locus_tag="OPY25_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HCS0928917.1"
                     /translation="MSPSDVPINWKRNLTVTWLGCFLTGAAFSLVMPFLPLYVEQLGV
                     TGHSALNMWSGLVFSITFLFSAIASPFWGGLADRKGRKIILLRSALGMAIVMLLMGMA
                     QNIWQFLILRALLGLLGGFIPNANALIATQVPRHKSGWALGTLSTGGVSGALLGPLAG
                     GLLADHYGLRPVFFITASVLFICFLLTFFFIRENFLPVSKKEMLHVREVVASLKNPRL
                     VLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNIAFISGMIASVPGVAALLSAPRL
                     GKLGDRIGPEKILIVALIISVLLLIPMSFVQTPWQLALLRFLLGAADGALLPAVQTLL
                     VYNSTNQIAGRIFSYNQSFRDIGNVTGPLMGAAISASYGFRAVFCVTAGVVLFNAIYS
                     WNSLRRRRLAIE"
     gene            complement(11829..12749)
                     /locus_tag="OPY25_003392"
     CDS             complement(11829..12749)
                     /locus_tag="OPY25_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxL/LpxP family Kdo(2)-lipid IV(A)
                     lauroyl/palmitoleoyl acyltransferasee"
                     /protein_id="HCS0928918.1"
                     /translation="MTKLPKFSVALLHPRYWLTWLGIGALWLVVQLPYPVIYKLGCAL
                     GHLARRVMKRRAKIAYRNLELCFPEMSAQERHTMVVKNFESVGMGVMETGMAWFWPDR
                     RVNRWMEASGLEHIREVKAQGLGFILVGIHFLTLEFGARMFGMHNPGIGVYRPNDNPL
                     LDWLQTWGRLRSNKSMLDRKDLKGMVKALKSGELIWYAPDHDYGPRASVFVPLFAVDQ
                     AATTSGTWMLARMSKACIIPSVPRRKPDGKGYELIILPAEYSPPLESAEATAAWMNKI
                     VEQCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            12969..14021
                     /locus_tag="OPY25_003393"
     CDS             12969..14021
                     /locus_tag="OPY25_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCS0928919.1"
                     /translation="MPVLHNRISNDELKAKMLAESEPRTTISFYKYFTIASPQQTRDA
                     LYQVFTALDVFGRVYLAHEGINAQISVPQSKVETFRQQLYTFDPALDGVRLNIALEDD
                     GKSFWVLRMKVRDRIVADGIDDPSFDASNVGDYLKAADVNAMLDDPDAVFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMLREHADKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARRAREQGLPVRFIGKNFVFDERMGERISDEVIAHCHQCGVSCDS
                     HTNCKNDGCHLLFIQCPQCASKFNGCCSEQCCEELALPEEEQRRRRAGRENGNKIFNK
                     SRGRLNSKLSIPDPAE"
     gene            complement(14073..14648)
                     /locus_tag="OPY25_003394"
     CDS             complement(14073..14648)
                     /locus_tag="OPY25_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HCS0928920.1"
                     /translation="MKKNLLGFTLASLLFTTGSAVAAEYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPSADKVNVTINTNSVDTNHAERDKHLRSAEFLNVAKF
                     PQATFTSTSVKKEGDELDITGNLTLNGVTKPVTLEAKLMGQGDDPWGGKRAGFEAEGK
                     IKLKDFNITTDLGPASQEVELIISVEGVQQK"
     gene            complement(14645..15217)
                     /locus_tag="OPY25_003395"
                     /pseudo
     CDS             complement(14645..15217)
                     /locus_tag="OPY25_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460129.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
BASE COUNT         3800 a         3779 c         4047 g         3612 t
ORIGIN      
        1 acaaagacaa aaaaaaacga agtgtgtcac gtcttgtgcg tattgccccc catgggaagc
       61 ataagaacat ccccatggcg gcataacaca caccaacact tcatttttta ggtgcgcgat
      121 acactatctt ctgtggccaa aaatcaatta taaaaaatca catggctatc gttttattag
      181 cactttggta tgagcttaaa taacaaaata ccacgcgtgg gtgagttatt aaaaatgttt
      241 ccacggacat actcttcatc gtaacgacgc gttaacaaaa aacgcatgtc gctaacaagg
      301 taatagataa ttttcgctat gtacgaccag gtccagggtg acagcatgaa aaacaaattg
      361 ttatttatga tgttgacaat actgggtgcg cctgggattg caaccgcgac aaattatgat
      421 ctggctcgtt cagagtataa ttttgcggta aatgaattaa gcaagtcttc atttaatcag
      481 gcggccatta ttggtcaagt cggcacggat aatagtgcca gagtacgcca ggaaggatca
      541 aaactattgt ccgttatttc acaagaagga gaaaataatc gggcgaaagt cgaccaggca
      601 gggaattata actttgcgta tattgagcaa acgggcaatg ccaacgatgc cagtatatcg
      661 caaagcgctt acggtaatag tgcggctatt atccagaaag gttctggaaa taaggccaat
      721 attacccagt acggtacgca gaaaacagca gttgtagtgc agaaacagtc gcatatggct
      781 attcgcgtca cccaacgcta ataccgttac gacttttaaa tcaatccgat gggggtttta
      841 ccatgaaact tttaaaagtg gcagcattcg cagcaatcgt agtttctggc agtgctctgg
      901 ctggcgtcgt tccacaatgg ggcggcggcg gtaatcataa cggcggcggc aatagttccg
      961 ggccggattc cacgttgagc atttatcagt acggttccgc taacgctgcg cttgctctgc
     1021 aaagcgatgc ccgtaaatct gaaacgacca ttacccagag cggttatggt aacggcgccg
     1081 atgtaggcca gggtgcggat aacagtacta ttgaactgac tcagaatggt ttcagaaaca
     1141 atgccaccat cgaccagtgg aacgctaaaa actccgatat tactgtcggt caatacggcg
     1201 gtaataacgc cgcgctggtt aatcagaccg catctgattc cagcgtaatg gtgcgtcagg
     1261 ttggttttgg caacaacgcc acggctaacc agtattaatt tagcgtctgc gctaataaaa
     1321 aaacagggcg taagccctgt tttttttcgg gaggaaatta tgcatacttt attgctcctt
     1381 gccgcacttt caaatcagat tacgtttacc acgactcagc aaggcgatat ttacacggtg
     1441 atccctcagg tcacattaaa cgaaccctgc gtctgtctgg tgcaaattct ctctgtgcgc
     1501 gacggcgtcg ggggacaaag ccatacacag caaaaacaaa cgctatcttt acctgctaat
     1561 caaccgattg agttgtctcg tcttagtgta aatatatctt cagaggactc ggttaaaatt
     1621 attgttactg tttcggacgg acaatcactg catttatcac aacaatggcc gccttctgca
     1681 cagtagtttt tgatggtggc ggaaatggat tggctgacct gggtattaaa gaggcgataa
     1741 aagcgtctca tcgtctcggc atgtcgctaa aaggtaacgc cgaaccctcg aggatgacta
     1801 atcattgagg agttaacatg tccgtaatca agaaaaatat ccctgccata ggcctgtgta
     1861 tctgcgcttt ttttatccat tctgcggtag ggcaacaaac ggtacagggc ggcgttatcc
     1921 attttcgcgg cgcgattgtt gagccactgt gcgatatttc tactcacgcc gaaaatattg
     1981 atttaacctg cctacgcgaa ggtaaaaagc aaatgcaccg gatagacctt cggcaggcat
     2041 ctggattacc gcaggatatt cagtccattg cgacggtacg gctgcattat ctcgatgcgc
     2101 aaaaaagcct ggcggtgatg aatattgagt accgttaacg gcggtgtcat agatataaaa
     2161 agagcgactc tgttgaaagc cctgctgtac actttgcaga taaggtgaga caaaaggggg
     2221 gggttatgac atcacgtctt caggtcatac agggtgatat cactcaactt agcgtcgatg
     2281 cgattgtgaa tgccgctaac gcatcattaa tgggcggcgg tggcgtagac ggcgcaattc
     2341 atcgcgcggc ggggccggca ttgctggacg cctgtaaact catccgtcag caacagggcg
     2401 aatgtcagac gggacatgcg gttatcacgc ctgctggcaa gctttcggca aaggcggtta
     2461 ttcacacagt ggggcccgtc tggcgaggcg gcgaacacca ggaagctgag ctactcgaag
     2521 aggcataccg gaattgtttg ctgcttgccg aggcgaatca ctttcgttcc atcgcttttc
     2581 cggcaatcag taccggcgtt tatggctatc cacgcgccca ggccgctgaa gtcgccgtca
     2641 ggacggtttc agattttatt acccgttacg ctctgcctga acaggtatac tttgtctgtt
     2701 atgatgaaga aactgcccgg ctttacgcaa gattacttac tcagcaaggc gacgaccctg
     2761 cctgataaaa cacgcctgga gcgtgccgtt gaaccgctat gcgcgcgcca tcccggagag
     2821 tgcggcattc ttgcgctgga taacagtctg gacgcttttg ccgcccgcta ccgcctgacc
     2881 gaaatggcgg cgcggacgct ggatgtgcag tattatattt gggaagacga tatgtccggg
     2941 cggctgctct tttcggttct gctgtcggcg gcgaagcgcg gcgttcatgt tcgtctgctg
     3001 ctggatgata acaatacgcc tggtctggat gatacgttgc gcttgctgga tagccatcct
     3061 aatatcgaag ttcgtctgtt taatcctttc tcttttcgta cgctacgcgc gctgggatat
     3121 ttgacggatt ttgcgcggct gaatcggcgg atgcacaata aaagttacac tgccgacggc
     3181 gtagtgacgc tggtcggtgg gcgcaacatc ggcgatgcct atttcggcgc tggcgaggag
     3241 ccgctatttt ccgatctgga cgtgatggcc attggcccgg tggtcaatga tgtcgccaat
     3301 gattttgaac gttactggcg ctgtagttca gtgtcgacat tgcagcaagt attatccctt
     3361 tctgagcagg aactgacgca gcgtatcgaa cttcccgaat cctggtataa cgatgagatc
     3421 acccgccgtt atctgcataa gctggaaacc agccagttta tggcggatct cgatcgcgga
     3481 acgttgccgc tgatttgggc aaaaacacgc ttgcttagcg atgacccttc taaaggcgag
     3541 gggaaggcgc agcgccattc gcttcttccg cagcgattat ttgacgtgat ggggtcgccg
     3601 acggagcgta tcgacattat ttccgcttac tttgtcccta cgcgcgcagg cgtggcgcag
     3661 ttgcttaatc tggtcaggaa aggtgtgaag atcgccatct taactaactc tctggcggcc
     3721 aacgatgtgg cggtcgttca cgcagggtac gcgcgctggc gcaagaaatt actgcgctat
     3781 ggcgtggagc tctacgaact gaaaccgacc cgcgaacatg aaaccgccgt acatgatcgc
     3841 ggactcaccg ggaactcagg ttccagctta catgctaaaa cgttcagtat tgatggtagt
     3901 aaggtgttta tcgggtcgct taattttgat ccccgttcaa cgcttttaaa taccgaaatg
     3961 ggctttgtca ttgaaagtga aacgctggcg acgcttattc ataagcgttt tacgcagagc
     4021 caacgcgatg cggcctggca actgcggctg gatcgctggg gacgaattaa ctggatcgat
     4081 cgtcagcaag aagaggaaaa ggtgttaaag aaagaacccg ctacgcgttt ctggcagcga
     4141 gttctggtac ggttggcggc aattttacct gtggaatggt tgctgtgaac ccgcgcgcgg
     4201 aaaactaccc gatcgcggcg cggctttctt gttttaccgg cggtttacct gaaaagagaa
     4261 atttcaggag cgggatgcgt aaatgaattt catacagaat taacgcaata cccataacaa
     4321 atatcagccc gcacaagaac ccgatcaggt tggaggagat atgcggtgta atatacgcgc
     4381 caaagaaaag cgttaaggga tgatgcacca gataaataaa cagcgaagca ttcacgaaat
     4441 aggtgacacg cgcggactga aagtttaaca agcgatgccc cagtgaaaat accacgttca
     4501 ccatccatag ccccattacc atcgtaatca cggattcggt ttcgtacatc caggcgtcgc
     4561 cgctcccata acgttgattc agcagatacg cgataaaagc aacggcagcg cctaaagtgc
     4621 atccgcgtga gggcgtggtg aagcgcgctt tcagatcggg gtgaatgaag gccaacgcgc
     4681 cgagaataaa aaacggcaca taaaatagcg tttgcatcac aataaaattg aacatgccgt
     4741 cactgaggat tgccggatat acgatgaata taatgcgcct gatagcagcg tacgccaccc
     4801 ccagcaggaa aaaaataagc gaaagtttgg ccagcgaaat agcggcggga cgaggcttgc
     4861 ttgtttcctg ccttttttgg aaccaggtaa aaatcccgat gctgacggtg gttaatatca
     4921 ccagcaccag taaaaaccac agatgtgaaa tgagttccca cgctaacgta ttatattttt
     4981 cataggcaga gagtgtaggc cagttctctg ttttctcttt gacatattgc aacaggataa
     5041 attgcggcaa ggtaagcaaa gggattgcgg taagcatggg aatacccaca cgttctaccc
     5101 gtactttcca ccagtgtttt aatggataac gtaaaaataa catgtacgaa aaataaccag
     5161 aaataacaaa aaacacctgc atacgaaaag cgtggataaa atcgttaaac agggttagcc
     5221 accacgatgg cgcggcgcta ttgacatgcc aactgtgagt ggaatagatc aacgagatat
     5281 gaaagggaat ccctaacaac atcagccatg cgcggataga gtcaagaaaa tattcacgcg
     5341 gcgcgggtac agagctcata taaggtcacg tattctcaga tttttcacct tatccataag
     5401 gcgaattata gttacattcg gtagcaaccc tacaccaact ccgacaacct gtctccagga
     5461 taagcacgca aagtgaaaac aggcgcggga ggtgcttaat ccatgagcca gcgcgctgaa
     5521 caaagcctgg attcagttgt cgtaatgcct gattatccat taaaatggat cggatcgata
     5581 taagcacaca aagggggaag tgcttactta ttatgaaaca taaacgacaa atgatgaaaa
     5641 tgcgttggtt gggcgcagct attatgttaa cgctctacgc atcatcgagc tgggcgttca
     5701 gtattgatga cgtggcaaaa caagctcaat ctttagccgg gaaaggctat gaggcgccta
     5761 aaagcaactt gccctccgtt ttccgcgaca tgaaatatgc ggattatcag cagatccagt
     5821 ttaacagcga taaagcctac tggaacaact taaagacccc ttttaagctc gaattttacc
     5881 atcaggggat gtacttcgat acgccggtca agattaacga agtgacggcg acgacggtca
     5941 aaagaatcaa atacagcccg gattacttca attttggcaa tgttcagcac gataaagaca
     6001 cggtaaaaga tttaggcttc gccgggttca aagtcctgta ccccattaac agtaaagata
     6061 agaacgacga aatcgtcagt atgcttggcg ccagctattt ccgcgttatc ggcgcaggcc
     6121 aggtgtatgg cttatctgcg cgcggcctgg cgattgatac cgccttacca tctggtgaag
     6181 agtttccccg ctttcgcgag ttctggattg agcgtccaaa acccaccgat aagcgtttga
     6241 ccgtctatgc attactggat tctccgcgcg cgaccggcgc ttaccgtttt gtgatcattc
     6301 ctggccgcga taccgtggtg gacgtgcagt caaaagtcta tctgcgcgat aaggtgggca
     6361 agctgggcgt tgcgccatta accagtatgt tcctgtttgg gccaaaccag ccgtcgccga
     6421 cgaccaacta tcgtccggaa ttgcatgact cgaacggctt atccattcat gcgggtaatg
     6481 gcgagtggat ttggcgtccg ctgaacaatc caaaacacct cgctgtgagc agctatgcga
     6541 tggaaaaccc tcagggattc ggcctgttgc agcgtggtcg cgagttctcg cgctttgaag
     6601 atttagacga tcgctatgac ctgcgtccaa gcgcctggat taccccgaaa ggcgactggg
     6661 gcaaaggtaa ggttgaactg gttgaaattc cgaccaatga tgaaaccaac gataacatcg
     6721 tcgcttactg gactccggat caactgccgg aaccgggtaa agagatgaac ttcaagtaca
     6781 ctctgacctt cagccgcgat gaagataaac ttcatgcgcc ggataatgcc tgggtgctgc
     6841 aaacacgccg ctcaacgggc gacgttaaac agtcgaatct gattcgccag cccgacggca
     6901 ctattgcctt tgtggtggat ttcgttggcg ccgacatgaa aaaactgccg ccggatacgc
     6961 ccgtcgctgc acaaaccagc attggcgata acggtgaaat cgttgacagt aatgtacgct
     7021 ataacccagt cactaaaggc tggcgtttaa tgctgcgcgt gaaagtcaaa gacgcgaaga
     7081 aaaccacgga aatgcgtgcc gcattggtga atgccgatca gacgctaagt gaaacctgga
     7141 gctaccagtt acctgccaat gaataaaaca actgagtata ttgacgcact gctgctttct
     7201 gaacgtgaga aagcggcatt gccgaaaact gacatccgcg ccgtgcatca ggcgctggat
     7261 gccgagcatc ggacttactc gcgagaagac gattcaccgc agggttccgt aaaagcccgc
     7321 cttgaacacg cctggccgga ttcattggcg aaggggcagt taattaaaga tgatgaaggg
     7381 cgcgatcagt tgcaggctat gccaaaagcg acgcgctctt cgatgtttcc tgatccctgg
     7441 cgaaccaacc cggttggccg tttctgggat cgcctgcgtg ggcgggatgt aacgccgcgc
     7501 tatgtttctc gtctgacaaa agaagagcag gcgagtgagc aaaaatggcg taccgtcggc
     7561 actatacgcc gctatatttt gttaattttg actctggcgc aaaccgtcgt cgcgacctgg
     7621 tatatgaaga ccattctgcc ctatcaggga tgggcgctca tcaatcctat ggatatggtg
     7681 gggcaggata tttgggtctc ctttatgcag ctcctgccct acatgctgca aaccggtatc
     7741 ctgattttgt ttgccgtgct gttctgctgg gtgtctgccg gattctggac ggcgctgatg
     7801 ggcttcctgc aactgcttat cgggcgcgat aagtacagta tctccgcgtc tacggttggc
     7861 gatgagcccc tcaatccgga acaccagacg gcgctgatca tgcctatctg taatgaagac
     7921 gttagccgcg ttttcgccgg tctgcgcgcg acctgggagt ccgttaaagc cacaggcaac
     7981 gccgcgcatt ttgacgtcta tatccttagc gatagttata acccggatat ctgcgtggcg
     8041 gagcaaaagg cgtggatgga gctcatcgcg gaagtgcagg gcgaaggcca aattttttac
     8101 cgtcgccgcc gccgccgtat gaaacgcaaa agcggcaata ttgacgattt ttgccgccgc
     8161 tggggcaatc agtacagcta tatggtggtg ctggacgcgg actcagtgat gagcggcgag
     8221 tgtctgagcg ggctggtgcg cctgatggaa gcgaacccta acgccgggat tatccagtct
     8281 tcgccgaaag cgtcggggat ggatactctg tatgcccgct gccaacagtt cgcgacccgt
     8341 gtttatggac cgctgtttac cgccgggctg cacttctggc agttggggga gtcgcactac
     8401 tgggggcaca atgccattat ccgcgtgaag ccgtttatcg agcactgcgc tctggcgccg
     8461 ctgccgggag aaggttcgtt cgccggatcg attctttccc acgactttgt ggaggcggcg
     8521 ctaatgcgtc gggcagggtg gggcgtctgg attgcctacg atctccccgg ctcctatgaa
     8581 gagctgccgc caaacctgct ggatgagctt aaacgcgacc gccgctggtg tcacggcaac
     8641 ctgatgaact ttcgtctgtt cctggtgaaa ggaatgcacc cggtgcatcg cgccgtgttc
     8701 ctgaccgggg taatgtcata cctgtccgcg ccgttatggt ttatgttcct cgcgctttct
     8761 accgcgctgc aggtcgttca tgcgttaaca gagccgcaat atttccttca gccgcgccag
     8821 ctttttccgg tctggccgca gtggcgtccg gaactggcaa tcgcgctgtt tgcgtcaacg
     8881 atggtgctgc tgttcctgcc gaagctgctc agtattatgc tgatctggtg taaaggcacc
     8941 aaagagtatg gcggtttctg gcgcgttacg ctgtcgctat tgctggaagt gctgttctcc
     9001 gtgttgctgg cgccggtgcg tatgctgttt cataccgtgt ttgtggtcag cgcgttcctc
     9061 ggctgggaag tggtctggaa ctcaccgcaa cgcgacgatg attctacgcc gtggggagaa
     9121 gcctttatgc gtcacggctc tcaactgctg ctggggctgg tctgggcggt gggtatggcg
     9181 tggctggatt tacgctttct gttctggctg gcgccgattg tcttttcgct gattctgtcg
     9241 ccatttgttt cggtgatctc cagtcgttca acggtaggat tacgcaccaa acgctggaag
     9301 ctgttcctga tcccggaaga gtattcgccg cctcaggtgt tggtcgatac cgataaatat
     9361 ctggagatga atcgccgccg tattctggac gatggcttta tgcatgcggt atttaacccg
     9421 tcgcttaatg cgctggcgac cgcgatggcc accgcgcgtc accgcgccag taaggtgctg
     9481 gaaatagccc gcgatcgtca tgtggagcag gcgctaaacg aaacgccgga gaaactgaac
     9541 cgcgatcggc gtctggtttt gctcagcgat ccggtgacga tggcgcgttt acactatcgg
     9601 gtctggaatg cgccagagag atactcttcc tgggtaaacc attatcagtc tctcgtcctg
     9661 aatccgcagg cgttgcaggg acgaacatcg tcagcgggat aaggtcttca ggtctggagt
     9721 gaggtgaaaa ataccggcgt gatgccggta tttttatagt gaaatgaggt atcaggtgcg
     9781 tatattcgcg gtgagcataa tggtgattac cctgagcggc tgcggcagta ttatcagcag
     9841 aacgatcccc ggacaaggac acggcaacca gtattaccct ggcgtgcagt gggatatgcg
     9901 tgattccgca tggcgctata tcactatcct cgatctgccc ttctcactga tcttcgatac
     9961 actgctactg ccgctcgata ttcaccacgg gccttatgag taattaacgc tcatcccatt
    10021 cgtctgccgc agtacggcct tcctcggtat caagcggggg ttcaagctgg aattcccctt
    10081 catcccattc atgcaaagta ttctcttcct gccattcctg gcggatctct atctcatcat
    10141 aatcgccgtc aaacacgctc tgtgcggctt caccactcag catcggcaga cattcgccat
    10201 cttcaccttc atcggcgaaa aattcgacct gccacatgat gtccccatcc tgcagtacat
    10261 atttctgaac gttgaactgc tgcacattcg cttcgtcttg ttcgaggcct ggatggtcag
    10321 ccagaaattc ttcccgggct gcatcgatag cttcttccag cgtggcatac atggtcatca
    10381 gtgtctccct ttgatttgac gaggtattta gggaaagaat agctgattct gtgatattgc
    10441 aagtatgaaa gcgcaaaaat cattctattg ccagtctgcg ccgtcgtaag ctgttccatg
    10501 aatagatagc attgaacaac accacgcctg ccgtgacgca gaatacggcg cggaagccat
    10561 agctcgcgga aattgcggca cccatgagag ggccggtgac gttgccgata tcgcggaaag
    10621 attggttgta actgaatatg cgcccggcta tctggttggt agagttgtaa accagcagag
    10681 tttgaacggc tggcagcagc gcgccatccg ccgcgccaag cagaaaccgc aatagcgcga
    10741 gctgccacgg cgtttgcaca aaagacattg gaatcagcag cagtacggaa ataatcagcg
    10801 cgacgataag gatcttttcc gggccaattc tgtcgccgag cttgccgagc cggggggcgc
    10861 taagtaatgc cgccacgccg ggaacggacg ctatcatccc gctaatgaac gcaatattac
    10921 tgacatttcc cgcgagttcg cgcacataga gcgtcaggat gggcgcaata gaccccgtcg
    10981 ccacctgaat aatcagcgtg gtgacaaaca ggcttaacac caggcgggga ttttttaacg
    11041 aggcgaccac ttcccgaacg tgaagcatct cttttttgct caccggcagg aaattctcgc
    11101 gaataaaaaa gaaggtgagc agaaaacaga taaacaaaac gctggcggta ataaaaaaga
    11161 ccgggcgaag gccgtaatgg tcggcgagca gaccgcccgc aagtgggcca agcagagcgc
    11221 cgctgacgcc gccagtagag agcgtcccta acgcccagcc gcttttgtgg cgcggcacct
    11281 gagtggcgat gagcgcattg gcgttgggaa taaatccgcc cagcaggcct aataacgcgc
    11341 ggaggatcag aaattgccag atattttgcg ccatgcccat taacagcatc acaatggcca
    11401 tgccgagagc ggaacgcaac agtatgatct tacgcccttt acgatccgcc agaccgcccc
    11461 aaaaagggga agcgatagct gaaaagagga acgtaatact aaagaccagc ccggaccaca
    11521 tgttgagcgc gctatggcct gttacgccga gttgctcaac gtagagaggg agaaaaggca
    11581 tgaccagact gaatgccgcg ccggttaaaa aacagcccag ccaggtaacg gttagattgc
    11641 gtttccagtt tatggggaca tcagagggtg acatagtgtt ccacagtatg atgcgcgttt
    11701 tgcgctatca tcaatttaat tatgagcgta ctaattataa ttatgcgccg accttaccag
    11761 cctcgcaatg tggggagctt ttaaagctaa aagaggggaa aaattgcagc ctgacggctg
    11821 caatcctgtc aatagcgcga cggtacgcct tcagggcgag ttttaaagcg gcgatgcagc
    11881 cacatatact gctctggcgc catcataatg cactgctcaa caatcttatt catccatgcg
    11941 gcagtcgctt ctgcgctctc cagcggaggc gaatattccg caggaaggat gatcagttcg
    12001 tagcctttcc cgtcgggttt acggcgaggc acggagggga taatacaggc tttagacatg
    12061 cgcgcgagca tccaggtacc ggaggtcgta gcggcctggt cgacggcgaa taacggtaca
    12121 aagacgctgg cgcgcgggcc ataatcgtga tccggcgcat accagatcaa ttcgccgctt
    12181 ttcaatgcct taaccatacc tttcagatct ttgcgatcca acatcgattt attggagcgt
    12241 aagcgccccc aggtctgtaa ccagtcgagc aacggattat cattcgggcg ataaacgccg
    12301 atacccgggt tatgcatacc aaacatgcgg gcgccaaact caagggtaag gaaatgtatt
    12361 cctaccagaa tgaaccccag cccctgcgcc ttaacttcac ggatatgctc cagaccgctc
    12421 gcttccatcc agcggttcac tcgccgatcg ggccagaacc aggccatgcc ggtttccatc
    12481 acgcccatac cgacggattc aaagtttttg accaccatgg tgtggcgttc ctgcgcgctc
    12541 atttccggaa agcataattc aaggttgcga taggcgattt tcgcgcggcg tttcattacg
    12601 cgtcgcgcca ggtggcccaa tgcgcaaccc aatttataga tgaccgggta ggggagttgc
    12661 acgaccaacc aaagcgcgcc tatacccaac caggttaacc aatagcgcgg gtgcagtaag
    12721 gccacggaga acttaggcaa cttcgtcatt tctatcctgt ctttcaacga acaattctcc
    12781 gtattctcgc atctttttgc gttgagcaaa aatatgtagc aggagagtgg cgattaaatc
    12841 gacaattgtt gttaattatt tagcgtaaag caggaaatgt agcgcaaaat gtgtggatgt
    12901 aaattggcga gacttgcctt atcatgcctg cccactttat tttttgctga ttgcaggata
    12961 cgtacaccat gccagtgtta cacaaccgca tctctaatga cgagctgaaa gccaaaatgc
    13021 tggcggaaag cgagccgcgt acgacaattt ctttttataa atatttcact atcgcctcgc
    13081 cgcaacagac gcgggacgcg ttgtatcagg tgtttacggc gttggacgtt tttggtcgcg
    13141 tttacctggc gcatgagggc atcaatgcgc aaatcagcgt gccgcaaagc aaggttgaga
    13201 cctttcgtca acagctttat acgttcgacc ccgcgctgga cggggtgcgt ttaaatatcg
    13261 cgctggagga tgacggaaag tcattttggg tgctgcgtat gaaagttcgc gaccgtatcg
    13321 tcgctgacgg tattgacgat ccgagttttg acgccagtaa tgtcggcgat tatctgaagg
    13381 cggcagatgt gaatgcgatg ctggacgatc ctgacgcggt ctttattgat atgcgcaacc
    13441 actatgagta tgaagtcggc catttcgaaa atgctctgga aatcccggcg gatacgtttc
    13501 gtgaacagtt gccaaaagcg gttgaaatgc tgcgggaaca tgcagataaa aagatagtga
    13561 tgtactgtac cggcggtatt cgttgtgaga aagccagcgc ctggatgaaa cacaacggtt
    13621 tcaataaagt ctggcatatt gagggtggca tcattgagta cgcccgtcgc gcgcgcgagc
    13681 aggggcttcc cgttcgcttt atcggcaaaa actttgtatt tgatgagcga atgggcgagc
    13741 gcatctcgga tgaggttatc gcgcattgcc atcagtgcgg cgtgtcctgc gatagccata
    13801 ccaactgcaa aaacgacggt tgccatctgc tgtttatcca gtgtccgcag tgcgccagta
    13861 aatttaacgg ctgctgtagt gaacaatgct gtgaagagtt ggccttgccg gaggaagaac
    13921 agcgccgacg tcgcgcgggt cgtgagaacg gcaacaaaat ttttaataaa tcgcggggtc
    13981 ggcttaatag caaactgagc attcccgatc cggctgagta atattttgcc ggatagcggc
    14041 gtaaaggctg ctatccggca tttcgccagg cgttacttct gctgaacgcc ttctactgag
    14101 atgataagct ccacctcttg tgaggctggg ccgagatcgg tagttatatt gaaatctttc
    14161 agcttaattt ttccttcggc ctcaaagccc gcgcgcttac cgccccacgg atcgtcgccc
    14221 tggcccatca gcttcgcttc cagcgtcacc ggtttagtca cgccattgag cgtcagattg
    14281 ccggtaatat ccagttcatc gccctctttt ttcacgctgg tagaggtgaa ggttgcctgc
    14341 gggaatttcg caacattaag aaactccgcg ctacgcaggt gtttgtcacg ttcggcatgg
    14401 ttagtgtcga cgctattggt gttaatggtc acattcactt tgtctgctga cggatttttt
    14461 tcgtcaaaag tgaacgtgcc gtcgaaatct ttaaaggtgc cgtatagcca gctgtagccc
    14521 agatgctgga tgcggaaatt gacgaacgca tgttggcctt ctttatcaat tttatactcc
    14581 gccgccacgg cggaaccggt cgtgaataac aaggatgcga gggtgaatcc cagcaggttt
    14641 tttttcattt ttgagctcca tagtcagatg acgacattcc tgtcatacgt ttcagtgtgt
    14701 cgtctttatc gatgaaatgg tgttttagcg ccataacccc atgcgagagc gagataatga
    14761 ccagcgacca ggcaaaccac agatgcagtg ttccggcgat gtcagcctgc gcgcccgcgt
    14821 ccgtaagcgt ggccggaatc tcaaaccagc caaagacgct aatcggttta ccgtcggcgg
    14881 tggaaatcag gtagccgcta atgattatcg caaagagcag gagatacaga aggatatgac
    14941 ccgcggcggc gccaatgcgc gttaaacggg aatagctggt caacgcaacg ggcggcggag
    15001 aataaagccg ccagataata cgcacgatca gcgccatcat cagtaacatg ccaatacttt
    15061 tatgtatttc cggcgcctag tgataccagc cgtcgtaata actgagcgtg accatccata
    15121 aacccaacgc aaacatgcca tagaccacta gggcggtcag ccagtggagg gcggcggaaa
    15181 ctacgccata acgttgtgga gtatttttaa attgcataaa cacaccaatg aatatttc
//
LOCUS       DAJVKX010000111        15137 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.111, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000111 DAJVKX010000000
VERSION     DAJVKX010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15137
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.111"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            546..2114
                     /gene="cydA"
                     /locus_tag="OPY25_003396"
     CDS             546..2114
                     /gene="cydA"
                     /locus_tag="OPY25_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HCS0928921.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLSKVQHMCVTWLVALGSNLSALWILVANGWMQNPIAADFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAYYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPASFTLFGIPD
                     QDKQENHLAIQIPYALGIIATRSVDTPVIGLKDLMVQHEERIRNGMKAYELLEQLRAG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVTDATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGKVLPTAVANSSLTVGDLLFSMFLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSTVTSQPAR"
     gene            2130..3269
                     /gene="cydB"
                     /locus_tag="OPY25_003397"
     CDS             2130..3269
                     /gene="cydB"
                     /locus_tag="OPY25_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HCS0928922.1"
                     /translation="MIDYEVLRFIWWLLVGILLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEDPRWRNMWDWGVFIGSFVPPLVIGVAFGNLLQGVPFHVDEYLRLYYTGN
                     FFQLLNPFGLLAGIVSVGMIITQGATYLQMRTVGELHLRARATSQIAALVTLVCFALA
                     GVWVMYGIDGYVVTSAIDHHAASNPLTKEVAREAGAWLVNFNNAPILWLVPALGVVLP
                     LLTILTSRMEKGAWAFLFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     MTLNLMTWVAAVFVPIILIYTSWCYWKMFGRITKEHIESNTHSLY"
     gene            3284..3397
                     /gene="cydX"
                     /locus_tag="OPY25_003398"
     CDS             3284..3397
                     /gene="cydX"
                     /locus_tag="OPY25_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HCS0928923.1"
                     /translation="MWYFAWILGTLLACAFGIITALALEHVEAGKTGQEES"
     gene            3534..3815
                     /gene="ybgE"
                     /locus_tag="OPY25_003399"
     CDS             3534..3815
                     /gene="ybgE"
                     /locus_tag="OPY25_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HCS0928924.1"
                     /translation="MKYIYAVMDKRLLRALSFVMAIVLAGCMFWDPLRFAARTSTLEI
                     WHGLLLMWAVCAGIIHGVGFRPESVHWQGIFCPLLADIVLIVGLIFFFL"
     gene            4044..4448
                     /gene="ybgC"
                     /locus_tag="OPY25_003400"
     CDS             4044..4448
                     /gene="ybgC"
                     /locus_tag="OPY25_003400"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HCS0928925.1"
                     /translation="MNKYMFRWPIRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQVLLAERVAFVVRKMTLEYYAPARLDDMLEVQTEITSMRGTALVFTQRIVNAENT
                     LLNEAEVLIVFVDPLKMKPRALPKSIVAEFKQ"
     gene            4445..5137
                     /gene="tolQ"
                     /locus_tag="OPY25_003401"
     CDS             4445..5137
                     /gene="tolQ"
                     /locus_tag="OPY25_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HCS0928926.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGRRDSLSGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELETLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            5141..5569
                     /gene="tolR"
                     /locus_tag="OPY25_003402"
     CDS             5141..5569
                     /gene="tolR"
                     /locus_tag="OPY25_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HCS0928927.1"
                     /translation="MARTRGRGRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPEANQSQAVSSNDDPPVIIEVSGVGQYSVVVDKDRMDQLPSEQVIAEVKRHLQAN
                     PKTVFLIGGAKEVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            5634..6764
                     /gene="tolA"
                     /locus_tag="OPY25_003403"
     CDS             5634..6764
                     /gene="tolA"
                     /locus_tag="OPY25_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HCS0928928.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHIILFAVLIWSSFDEHIEASAGG
                     GGGSAIDAVMVDPGAVVQQYNRQQDQQASARGAEEERKKLQQQQAEELQQKQAAEQER
                     LKQLEKERLAAQEQQKQAEEAAKLAQQQQQAEEAAKAAADAKKKAEAEAAKAAADAKK
                     KAEAEAAKAAADAKKKAEAEAAKAAAEAKKKAEAEAAKAAADAKKKADAEAAKAAAEA
                     KKKADAAAAKAAADAKKKAAAEKAAAAEGVDDLLGDLSSGKNAPKTGGGAKGNGQPSK
                     DSGTSGANGGTTGADISAYAKQIQVAIQSRLYDASLYQGKQCVLHISLAPDGSLKSIT
                     SEGGDPALCQAALMATKTAKIPKPPSQAVYEKIKDAKLDFKL"
     gene            6888..8180
                     /gene="tolB"
                     /locus_tag="OPY25_003404"
     CDS             6888..8180
                     /gene="tolB"
                     /locus_tag="OPY25_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HCS0928929.1"
                     /translation="MKQALRVAFGFLMLWAAVLHAEVRIEITQGVDSARPIGVVPFKW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRSRLPQQPATAQEVQPTAWSALGIDAVIVG
                     LVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGTKLAFALSKTGSLNLYVMDLA
                     SGQIRQITDGRSNNTEPTWFPDSQTLAFTSDQAGRPQVYKMNINGGAAQRITWEGSQN
                     QDADVSSDGKFMVMVSSNNGQQHIAKQDLVTGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAWSPYL"
     gene            8215..8739
                     /gene="pal"
                     /locus_tag="OPY25_003405"
     CDS             8215..8739
                     /gene="pal"
                     /locus_tag="OPY25_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HCS0928930.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGGMLNGAGTG
                     MDANGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAAMLDAHANFLRSNPSY
                     KVTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHD
                     EAAYAKNRRAVLVY"
     gene            8749..9537
                     /gene="cpoB"
                     /locus_tag="OPY25_003406"
     CDS             8749..9537
                     /gene="cpoB"
                     /locus_tag="OPY25_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HCS0928931.1"
                     /translation="MSSNFRHHLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVMERQKQIMLQLGSLN
                     NGGAAQPAAGDQSGAATAATPAPDAGTATSGAPVQSGDANTDYNAAIALVQDKSRQDD
                     AIVAFQNFIKKYPDSTYQPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAADA
                     MYKVGVIMQDKGDTAKAKAVYQQVINKYPGTDGAKQAQKRLNAM"
     gene            9702..9774
                     /locus_tag="OPY25_003407"
     tRNA            9702..9774
                     /locus_tag="OPY25_003407"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9735..9737,aa:Lys,seq:ttt)
     gene            9920..9995
                     /locus_tag="OPY25_003408"
     tRNA            9920..9995
                     /locus_tag="OPY25_003408"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9953..9955,aa:Lys,seq:ttt)
     gene            10130..10205
                     /locus_tag="OPY25_003409"
     tRNA            10130..10205
                     /locus_tag="OPY25_003409"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10163..10165,aa:Lys,seq:ttt)
     gene            10499..11542
                     /gene="nadA"
                     /locus_tag="OPY25_003410"
     CDS             10499..11542
                     /gene="nadA"
                     /locus_tag="OPY25_003410"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HCS0928932.1"
                     /translation="MSVMFDSQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEK
                     NVLMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIEHLDSLGEKIIWAPDRHLGNYVQKQTRADVLCWQGACIVHDEFKTQALTRLKKIY
                     PDAAILVHPESPRSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEIQVDAALRESALLP
                     LNRMLDFAATLRV"
     gene            11567..12286
                     /locus_tag="OPY25_003411"
     CDS             11567..12286
                     /locus_tag="OPY25_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HCS0928933.1"
                     /translation="MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEN
                     ISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAANIYGWYAWSRQTKDNEAELKIR
                     WLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIA
                     VNGSRLWINSARERGSRALSR"
     gene            complement(12283..13221)
                     /gene="zitB"
                     /locus_tag="OPY25_003412"
     CDS             complement(12283..13221)
                     /gene="zitB"
                     /locus_tag="OPY25_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HCS0928934.1"
                     /translation="MAHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGS
                     LALLADAGHMLTDAAALLFALLVVQFSRRPPTVRHTFGWLRLTTLAAFVNAIALVVIT
                     LLIVWEAIERFYTPRPVAGNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHV
                     MGDLLGSVGAIVAALIIIWTGWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPV
                     SLDINALQRHLSREIPEVRNVHHVHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFL
                     MHEYHIAHATIQMEYQMCHGPDCHLNQTPSGHVHHH"
     gene            complement(13332..13718)
                     /locus_tag="OPY25_003413"
     CDS             complement(13332..13718)
                     /locus_tag="OPY25_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HCS0928935.1"
                     /translation="MKMTKLTTLLLTATLGLASGAALAAESNAQSSNGQANSAANAGQ
                     VAPDARQNVAPNDVNNNDINTNGNTNSTMQHPDGSTMNHDGMTKDEEHKNTMCKDGRC
                     PDINKKVETGNGVNNDVNTKTDGTTQ"
     gene            14038..15090
                     /gene="aroG"
                     /locus_tag="OPY25_003414"
     CDS             14038..15090
                     /gene="aroG"
                     /locus_tag="OPY25_003414"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HCS0928936.1"
                     /translation="MNYQNDDLRIKEINELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPAAAKEYAARLLALRDELQGELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKAPNYSAQHVAEVKEGLIKAGLTPQVMIDFSHANSCKQFQ
                     KQMEVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGQPLTYGKSITDACIGWEDT
                     DALLRQLSAAVKARRG"
BASE COUNT         3632 a         3658 c         4194 g         3653 t
ORIGIN      
        1 tttagcaata attgaacatc aatgtggaat gttttttact ggatgcgggg cagtaaaaaa
       61 cgcacaaaat gtttagcctt atcgaataag cctcttttta cagggggttt gaaattactc
      121 tttgcaaaaa caaaaagtta acaaaaaatt caccatgcat tcaatgaata aacattatta
      181 acattaactt taaaaattga ttttaatcaa tatttaaatg ttggaaaaga gcatcaaaac
      241 tggttaaatt gtccgtgatc aaattccctg aaaagcgata gattagccat aaattgatcg
      301 ctgtcgaaaa aagcaaatct gacccactaa aaacctgttt attgtaaggg ttttacggcg
      361 taatatattt gcgggatcaa tttgggtttt ttattaacat gtttgtaact tttcatcatt
      421 actgtttcct tcccgagggg atagtacgat ggaaggccgc aaataaattt gtattggggc
      481 atgcgtgtga ccctttctaa cggggttcac tctcggagtc ttcatgcgat gagcaaggag
      541 tcatgatgtt agatatagtc gaactgtcgc gcttacagtt tgccttgacc gcgatgtacc
      601 acttcctgtt tgtgccgcta acgctcggta tggcgttcct gctggccatt atggaaacgg
      661 tatacgtcct ttccggcaaa cagatttata aagatatgac caagttctgg ggcaagttgt
      721 ttggtatcaa ctttgctctg ggtgtggcta ccggtttgac catggagttc cagttcggga
      781 caaactggtc gtactactcc cactatgttg gggacatctt cggtgcgccg ctggccatcg
      841 aaggtttgat ggccttcttc ctcgaatcca cctttgtagg tctgttcttc ttcggctggg
      901 atcgtctaag taaagttcag catatgtgcg tcacctggct ggtggctctg gggtccaacc
      961 tctccgcgtt gtggattctg gtagcgaacg gctggatgca aaacccaatc gctgcggatt
     1021 tcaatttcga aaccatgcgt atggaaatgg tgagcttctc tgaactggtg ctgaacccgg
     1081 tagcacaggt gaaatttgtt cacactgtgg cgtccggcta tgtcaccggc gcgatgttca
     1141 tcctcggtat cagcgcttac tacatgctga aaggtcgtga cttcgccttt gctaaacgct
     1201 cctttgctat tgccgccagc ttcggtatgg ctgccgtact gtccgttatc gtactcggtg
     1261 acgaatccgg ttacgaaatg ggcgacgtgc agaaaaccaa gctcgctgcg attgaagctg
     1321 aatgggaaac gcaacctgct ccggcctcct ttaccctgtt cggcattcct gaccaggaca
     1381 aacaggaaaa ccatctggcg attcagatcc cttatgcgct cggcattatc gctacgcgtt
     1441 ccgtggacac gccggttatt ggcctgaaag atctcatggt tcagcatgaa gagcgtatcc
     1501 gtaacgggat gaaagcttat gagctgctgg agcagctgcg cgccggttct accgaccagg
     1561 ccgttcgcga ccagtttaac agcatgaaga aagatctcgg ttacggcctg ctgctgaaac
     1621 gctatacgcc taatgtgact gacgcgaccg aagcgcagat ccagcaagcg acgaaagatt
     1681 ctattcctcg cgttgcgccg ctgtacttcg ctttccgtat catggtggcg tgcggcttcc
     1741 tgctgctggc gattatcgca ctttccttct ggagcgtgat tcgtaaccgc atcggtgaga
     1801 aaaaatggct gttgcgtgcg gcgctgtacg gtattccact gccgtggatt gcggttgaag
     1861 caggttggtt cgtcgccgag tatggtcgtc agccgtgggc gatcggcaaa gtgttgccga
     1921 cagccgtggc gaactcatcg ctgaccgtgg gcgatctgct gttctccatg ttcctgattt
     1981 gcggcctgta taccctgttc ctggtggcag aattgttcct gatgttcaaa tttgcacgcc
     2041 ttggcccaag cagcctgaaa accggtcgct atcactttga gcagtccacc gtgacttctc
     2101 agccggcacg ctaagacagg agtcgtcaaa tgatcgatta tgaagtacta cgttttatct
     2161 ggtggctgct ggttggcatt ttgctaattg gtttcgccgt caccgatggg ttcgacatgg
     2221 gggtggggat gctcacccgt ttcctcggtc gtaacgatac cgaacgtcga attatgatta
     2281 actctatcgc cccgcactgg gacggtaacc aggtgtggtt gatcaccgcg ggcggcgcgt
     2341 tgtttgctgc ctggccgatg gtttacgccg cggcgttctc cggtttctat gtggcgatga
     2401 tcctggtgct ggcgtctttg ttcttccgtc cggtcggttt tgattaccgt tccaagattg
     2461 aagacccgcg ctggcgcaac atgtgggact ggggcgtgtt catcggtagc tttgtgccgc
     2521 cgctggtgat tggcgtggcc tttggcaacc tgttgcaggg cgtaccgttc catgtggatg
     2581 agtatctgcg tctgtactat accggtaact tcttccagtt gctgaacccg tttggtctgc
     2641 tggcgggtat cgtaagcgta gggatgatca tcacgcaggg ggcgacttac ctgcaaatgc
     2701 gtaccgttgg cgaactgcac ctgcgcgcgc gcgccacctc gcagattgcg gcgctggtga
     2761 cattagtgtg ctttgcgctg gcgggcgttt gggtaatgta tggtattgat ggttatgtcg
     2821 tgacatccgc gattgatcat catgctgcct ctaacccgct gactaaagaa gtggcgcgcg
     2881 aagccggcgc ctggctagtg aactttaata atgctccgat cctgtggttg gttccggctc
     2941 tgggcgtggt tctgccgctg ctgactatcc tgacttcccg tatggagaaa ggcgcgtggg
     3001 cattcctgtt ctcttcgctg acgttggcct gcattattct gacggcgggt atcgctatgt
     3061 tcccatttgt gatgccgtcc agcacgatga tgaatgccag tctgaccatg tgggatgcga
     3121 catccagcca gatgacgctg aacctgatga cctgggttgc ggcggtgttc gtaccgatta
     3181 ttctgatcta caccagctgg tgttactgga aaatgttcgg tcgtatcact aaagaacata
     3241 ttgaaagcaa cacccactct ctgtactaag taaggagctt aaaatgtggt atttcgcatg
     3301 gattctggga acgcttcttg cctgtgcatt cgggatcatt accgccctgg cgcttgagca
     3361 cgttgaagcg ggtaaaaccg gtcaagaaga aagctaatga ttcatattgt cgctatgcaa
     3421 tatacaaaat catttaagtt gcatcgcggc ggcaaggctg cgaatcccca ggagcttaca
     3481 tcagtaagtg actggggtga gcagccgcag ccaacaaaga ggcagcttag aggatgaagt
     3541 atatttatgc ggtaatggac aagcgcctct taagggcgct ttccttcgtg atggcgatag
     3601 tgctggcagg atgtatgttc tgggacccgt tacggtttgc cgccaggacc agcacgcttg
     3661 aaatctggca cggattattg ctgatgtggg cggtttgcgc aggcataatc cacggcgtgg
     3721 gttttcgccc tgaatccgta cactggcaag ggattttttg tccgctcctt gcggatatcg
     3781 tccttatcgt cggcctgatt ttcttcttct tgtgaataag aaacctcctt aaaaatatag
     3841 gggcttgcat aagcccatat atttttactc tcccttaact tccccccatt cccaagcctc
     3901 attcctacgc gtatagtagc aacgtttaaa agctctactt ttgttgcatt accgggatgt
     3961 aaagtgaata caaggcgata tacaacggca ttcttgaggc attacggcgg caagcggatg
     4021 acgccaacaa agaggctgca gggatgaata agtatatgtt tcgatggcca attcgagttt
     4081 attacgaaga cacggacgcc ggcggtgtgg tttatcacgc cagctatgtc gctttttatg
     4141 aaagagcgcg cacggagatg ctgcgtcacc atcacttcag ccaacaggtg ctgctggcgg
     4201 agcgggtcgc ctttgtggtg cgcaagatga cgctggaata ctatgcgcct gcgcggctcg
     4261 acgatatgct tgaagttcaa acagaaatta cgtcaatgcg tggcaccgct ttggttttca
     4321 cgcaacgcat tgtcaacgca gagaacacgc tgctaaatga agcagaggtt ctgattgttt
     4381 tcgttgatcc actcaaaatg aagcctcgtg cgcttcctaa gtctattgtc gcggagttta
     4441 agcagtgact gacatgaata tccttgattt gttcctgaag gcaagccttc tagttaaact
     4501 tatcatgttg attttgattg gtttttcaat agcatcctgg gccatcatta tccagcgaac
     4561 gcgtatcctg aacgccgctg cgcgtgaggc ggaagcgttt gaagataaat tctggtccgg
     4621 aatcgaacta tcgcgtctgt accaggaaag ccaggggaga cgcgatagtc tgtcgggctc
     4681 ggaacaaatc ttttatagcg ggttcaaaga gtttgtccgg ctccatcgcg ccaacagcca
     4741 tgcgccggag gcagtggtag agggggcgtc gcgtgcgatg cgcatctcca tgaaccgaga
     4801 gctggaaacg ctggaaacgc atatcccgtt tcttggcacg gtaggctcta tcagtcctta
     4861 tatcggtctg tttggcaccg tatgggggat tatgcatgcg tttatcgccc tgggtgcggt
     4921 gaaacaggcg actctgcaaa tggttgcgcc gggtattgcc gaagcattga ttgccacggc
     4981 gattggtctg tttgccgcta tccctgcggt tatggcttac aaccgactga atcagcgcgt
     5041 gaacaagctg gaactgaatt acgacaactt tatggaagag tttaccgcga ttctgcaccg
     5101 ccaggcgttt accgtaagcg aaagcaacaa ggggtaagcc atggccagaa cgcgtggacg
     5161 aggtcgtcgc gaacttaagt ccgaaatcaa tatcgtaccg ctactcgacg tactgttggt
     5221 gctgctgctg atctttatgg caaccgcgcc gatcattacc cagagcgtgg aagtcgactt
     5281 accggaggcg aatcagtcgc aggcggtcag tagtaacgac gatccgccgg tcattattga
     5341 ggtttccgga gtagggcaat acagcgtagt ggttgataaa gatcgaatgg atcaactgcc
     5401 gtctgaacag gtgatcgcag aagtaaagcg tcatctgcag gctaatccga aaacagtctt
     5461 tttaatcggc ggcgcgaaag aggtgccgta cgatgaaata attaaagcgc tgaacttgtt
     5521 acacagcgcg ggcgtaaaat cggttggctt aatgacgcag ccaatctgaa gtctgcgtcc
     5581 cgttggcttg aaagacggcg agtaacaggc gaacagtttt ttgggaaccg agagtgtcaa
     5641 aggcaaccga acaaaacgac aagctcaaac gggcgataat tatttcagcc gtgctgcata
     5701 tcatcttatt tgcagtgctg atctggagtt cgtttgatga gcatatagag gcttctgccg
     5761 gcggcggcgg cggttccgct atcgacgcgg tgatggtcga tcctggcgcc gttgtgcagc
     5821 agtacaaccg tcagcaggat caacaggcca gtgccagagg cgcggaagaa gagcgtaaaa
     5881 agctgcaaca gcagcaagca gaggagctgc agcagaagca ggctgctgaa caggagcggt
     5941 tgaaacaact tgagaaagaa cgtttagcgg ctcaggagca gcaaaagcag gctgaagaag
     6001 cggcaaaact ggcgcaacag cagcaacagg ccgaagaagc ggcgaaagcg gcggcggacg
     6061 cgaagaagaa agcggaggcc gaggcggcga aagcggcggc ggacgcgaag aagaaagcag
     6121 aggccgaggc ggcgaaagcg gcggcggacg cgaagaagaa agcagaggcc gaagcggcga
     6181 aagcagcggc ggaggcgaag aagaaagcgg aggccgaagc ggcgaaggca gcggcggacg
     6241 ctaagaagaa agcggatgcc gaggcggcga aagcggcggc ggaggcgaag aagaaagcgg
     6301 atgccgcggc ggcgaaagca gcggcggacg ctaagaagaa agcggctgcc gaaaaagcgg
     6361 ccgccgcaga aggcgtcgac gatctgcttg gcgatctcag ctcgggtaag aatgcgccga
     6421 aaaccggcgg cggcgcgaaa gggaatggtc agccatcgaa agatagcggt acatcgggcg
     6481 ctaacggtgg gacgacaggc gctgatatca gcgcctacgc gaaacagatt caggtcgcca
     6541 ttcagagccg tctgtatgat gcgagcctgt atcagggcaa acaatgtgtc ttgcatatta
     6601 gcctggcgcc ggatggctca ttaaaaagca ttacgtctga gggcggcgat ccggcgcttt
     6661 gtcaggcggc gttaatggcg acaaaaaccg cgaaaattcc taaaccgcca agccaggctg
     6721 tttatgagaa aataaaggat gccaaactag actttaaact gtagatactt ttctttatgg
     6781 aagttggagc ggttgagttg ttactggtcc tggtggtttt gtgtatttga gtttgttaac
     6841 attctgctaa attatcgtgg gtcgcaggcc caggtatggg agatatgatg aagcaggcat
     6901 tacgagtagc atttggtttt ctgatgctgt gggcggcagt gctgcacgca gaagtccgta
     6961 tcgagatcac ccagggggtg gactcggcgc gaccgattgg cgttgtgcct tttaaatggg
     7021 ccgggccggg cgctgcgcct gaagatatcg gcggcatcgt ggcggcagat ttacgcaata
     7081 gcggtaaatt taatccgtta gaccggtccc gactgccgca gcagccagcc accgctcagg
     7141 aagttcagcc taccgcatgg tctgcgctgg gtattgatgc cgtcatcgtt ggactggtca
     7201 cgccgaatcc ggacggttcg tacaatgttg cttatcagct ggttgacact ggcggtgcgc
     7261 cggggactgt actggcgcaa aactcctata aagtgaacaa gcagtggctg cgttatgcag
     7321 gccacaccgc cagtgacgaa gtctttgaaa aactgacggg cattaagggc gcgttccgta
     7381 ctcgtatcgc ctatgtggta cagactaacg gcggtcagtt cccgtatgaa ctgcgtgtgt
     7441 cggattacga tggctacaat cagttcgtag tgcaccgttc tccgcagccg ttgatgtctc
     7501 cggcgtggtc tccggacggc tcaaaactgg cttacgtgac ttttgaaagc ggtcgctccg
     7561 cgctggttat ccagacgctg gcaaacggcg cagtgcgtca ggttgcgtcc ttcccgcgtc
     7621 acaacggcgc gccggccttc tcgccggatg ggacgaaact ggcgttcgcg ttatcgaaaa
     7681 ccggaagtct gaacctgtac gttatggatc tcgcctccgg tcagattcgt cagataacgg
     7741 acgggcgtag caacaatacg gagccgacct ggttcccgga cagccagact ctggccttta
     7801 cttctgacca ggctggacgt ccgcaagtgt ataaaatgaa cattaacggc ggtgcggcgc
     7861 agcgtattac ctgggaaggt tcgcaaaacc aggatgcgga tgtcagcagc gacggtaaat
     7921 ttatggtaat ggtaagctca aataacgggc agcagcacat tgccaaacaa gatctggtga
     7981 cgggtggcgt acaggttctg tcgtcaacgt tcctggatga aacgccaagt ctggcaccta
     8041 acggcacgat ggtaatctac agctcttctc aggggatggg atctgtgctg aatttggttt
     8101 ctacagatgg gcgtttcaaa gcgcgtcttc cggcaactga tggtcaggtg aaatcgcctg
     8161 cctggtcgcc gtatctgtga taataattaa ttgattacta aaggaattaa agaaatgcaa
     8221 ctgaacaaag tgctgaaggg cctgatgatt gccctgcctg ttatggcaat cgcggcatgt
     8281 tcttccaaca agaacgccag caatgacggt agcgaaggcg gcatgctgaa cggcgccggc
     8341 actggtatgg acgctaacgg caacggcaac atgtcatctg aagagcaagc gcgtctgcag
     8401 atgcagcagc tgcagcagaa caacatcgtt tacttcgatc tcgacaagta cgatatccgt
     8461 tctgacttcg cggcaatgct ggatgcgcac gctaacttcc tgcgtagcaa cccgtcttac
     8521 aaagtcaccg tagaaggtca cgcggacgaa cgcggtactc cggagtacaa catctccctg
     8581 ggcgaacgtc gtgctaacgc cgttaaaatg tacctgcagg gtaaaggcgt ttccgctgac
     8641 cagatctcca tcgtttctta cggtaaagaa aaacctgccg tactgggcca cgacgaagcg
     8701 gcttacgcta agaaccgtcg cgctgtactg gtttactaag agaattgcat gagcagtaac
     8761 ttcagacatc acctgttgag tctgtcgtta ctggttggca tagcggcccc ctgggccgct
     8821 tttgctcagg cgccaatcag tagtgtcggc tcaggctcgg tcgaagaccg cgtcactcaa
     8881 cttgagcgta tctctaacgc tcacagccag cttttaaccc aacttcagca gcagctctcc
     8941 gataatcagt ctgatatcga ttctttgcgc ggccaaatcc aggaaaatca gtatcaactg
     9001 aatcaggtga tggagcgcca gaagcaaatt atgctgcagc tggggagttt aaataatggc
     9061 ggcgcagcgc agccagcagc tggcgaccag agcggggcgg caaccgctgc gacccccgct
     9121 ccggatgccg gtacggcaac ctcaggggcg ccggtacaaa gtggcgatgc gaataccgat
     9181 tacaatgcgg caattgcgct ggtgcaggat aagtctcgcc aggatgatgc gattgtggcg
     9241 tttcagaact tcatcaagaa ataccctgat tctacttatc agccgaacgc caattattgg
     9301 ctgggccagt tgaattacaa caagggtaaa aaagatgacg ccgcctatta tttcgcctcg
     9361 gtagtaaaaa actatcctaa gtcgccgaag gctgcggacg cgatgtacaa agttggcgtt
     9421 atcatgcagg acaaaggtga tacggcaaaa gcgaaagcgg tttatcagca ggtgattaac
     9481 aaatatcctg gcactgatgg cgcgaaacag gcgcagaagc gtcttaacgc gatgtaatgc
     9541 gtaccatgcg accagaaaac gccttttttc tggtcgcgtc gtgcgattcc taagcagttg
     9601 agccctctgc gtcgaaattt ttgttgcgct caaatctgaa atcagtaata tatgccgccg
     9661 ttgccacggg atattaaaca actcgaaagc aacgtaaaag tgggtcgtta gctcagttgg
     9721 tagagcagtt gacttttaat caattggtcg caggttcgaa tcctgcacga cccactaatt
     9781 taacatcaaa ctcagatgtt gaacgtgaag gataacgttg cgtcagcaac ggcccgtagg
     9841 gcgaggcgaa gccgagtcat cctgcacgac ccaccatctt tagatggtcc gagtaaaatc
     9901 tttcaggcag cacccgtatg ggtcgttagc tcagttggta gagcagttga cttttaatca
     9961 attggtcgca ggttcgaatc ctgcacgacc caccaatata caaggtggta actggtagag
    10021 aacgtgaagg ataatgttgc tttagcaacg gcccgaaggg cgaggcgaag ccgagtcatc
    10081 ctgcacgacc caccatcctg aatgattgaa gcagtaaccc ttatccaagg ggtcgttagc
    10141 tcagttggta gagcagttga cttttaatca attggtcgca ggttcgaatc ctgcacgacc
    10201 caccaatgta aaaaagcgcc ctaaaggcgc ttttttgcta tctgcgatat ggaagattcg
    10261 aacctgccgc aggttcgggt cttgcctgat gcgctgcgct tatcaggcct acagacggca
    10321 ccgctcacgt aggccagata agacgttacg ccgccatcag atacggacta cgtaattatt
    10381 gtgactttcc ttattgaatc agctatcttg tttagcatat aaaacaaatt gaccgattgt
    10441 ggcgtttatt acgctttcat tcggttgttt cgttaagtca gtaaaacgag aagccacgat
    10501 gagcgtaatg tttgactcac aagccgcaat ctacccgttc ccgccgaaac caacgccgtt
    10561 gaacgacgat gaaaagcaat tttatcgtga gaaaatcaag cgtttgctca aagagcgcaa
    10621 tgccgtcatg gtggcgcact actacaccga tccggaaatt caacagttag cagaagaaac
    10681 cggcggctgt atttccgact cgctggaaat ggcccgtttc ggcgcgaagc acgccgcatc
    10741 cacgttactg gtagcgggcg tacggtttat gggggaaacc gccaaaatcc tcagcccgga
    10801 aaaaaacgtt cttatgccta cgctggcggc ggaatgttcg ctggatttag gctgcccaat
    10861 agacgaattt agcgcttttt gtgatgcgca ccctgacaga accgtagtgg tctatgctaa
    10921 cacctcggct gctgttaaag cgcgtgcgga ctgggttgtg acctccagta tcgccgtaga
    10981 actgattgag catctggata gtttggggga aaaaattatc tgggcgccgg acagacacct
    11041 ggggaattac gtgcaaaaac agaccagggc cgatgtactg tgttggcaag gggcgtgtat
    11101 cgtgcatgac gagtttaaaa cccaggcgtt gacccgttta aaaaaaatct atcccgatgc
    11161 cgctattctg gttcaccctg aatcgccgcg gtccattgtc gagatggccg atgcggtggg
    11221 ctccaccagt cagcttatta aggcggcaaa aacgctgccg cacagacagc ttatcgtcgc
    11281 gaccgatcgc ggcatcttct acaaaatgca gcaggcggtt ccggataaag agttgcttga
    11341 agcaccaacg gcgggcgaag gggcaacctg tcgcagctgc gcgcattgtc cgtggatggc
    11401 gatgaacggc ctgaaagcca ttgctgaagg gctggagcag ggaggcgcgg cgcatgaaat
    11461 acaggttgat gcggcgctac gcgagagcgc attacttccc ctcaaccgga tgctggattt
    11521 tgcggctaca cttcgggtgt aaagacggaa atctttgggg gagagaatgg atttttttag
    11581 tacgcacaac atactgattc atattccgat tggcgctggc gggtacgatc tctcatggat
    11641 cgaagcggta ggaaccatcg ccggcctgct ctgtatttgg cttgccagtc tggagaatat
    11701 cagcaactac ttttttggac tggttaacgt caccctgttt gcgattattt tctttcagat
    11761 ccagctttat gccagcctgt tgctgcaact ctttttcttt gccgccaata tttatggctg
    11821 gtatgcgtgg tcgcggcaaa caaaggataa tgaggccgag cttaaaatac gctggctgcc
    11881 gttgccaaaa gcaatggcat ggctggcgat atgtgtgata gctatcggtt tgatgacgcg
    11941 atatatcgat cccgtattcg ccgtcctgac gcgcgtggcc gtcgccatta tgcagatgct
    12001 ggggttacag gtgacaatgc ctgtactgca accggacgct ttcccgttct gggactcttg
    12061 catgatggtg ctgtctatcg tggcgatgat tttgatgaca cgcaaatatg tcgaaaactg
    12121 gctcctgtgg gtgataatca acgtaatcag tgtggtgatt tttgctttgc agggcgtcta
    12181 tgcgatgtcg ctggaatatc tgatcctgac atttatcgcc gtgaacggta gtcgcctgtg
    12241 gataaacagc gcgcgggagc gaggatcgcg cgcgctttcc cgttaatggt gatgaacatg
    12301 cccggatggc gtctgattca ggtgacagtc cgggccgtga cacatttgat actccatttg
    12361 aatcgtagcg tgcgcaatat ggtattcgtg catcaggaaa tcctggatac gttccagcag
    12421 cgcatcatgg tcgtgtggcg gaatgacctg agcgtgcaat gtcatgactg gtttttcgcc
    12481 gaccatccag acatgcacat ggtgtacgtt gcggacttcg gggatttccc ggcttaaatg
    12541 gcgctgtaag gcattaatat ccagtgaaac cggcgcgcct tccagcaatt cgttgacgct
    12601 atcttttaac aaacgccagg cgctgcgtag taccagtacc gaaaccagaa tagagagaat
    12661 cgggtccgct ggcgtccagc ccgtccagat aatgatcaac gcggcgacta ttgcgccgac
    12721 ggaacccagc aaatcgccca tcacatgtag cgcggcagcg cgcacgttca ggtttttttc
    12781 atcgcttccc cgatggagta tccagaacgc aaacaggttc gccagcagac ccgcgaccgc
    12841 aatcaccatc atcagattgc ccgccaccgg acgtggcgtg taaaagcgct ctatcgcttc
    12901 ccagacaatg agaagggtaa tgaccaccaa cgcaatggca ttcacaaagg ccgccagtgt
    12961 ggtgagtctt agccagccaa aagtgtggcg aacagtcggg gggcgacggg aaaattgaac
    13021 caccagcagc gcaaagagaa gagccgccgc gtcggtgagc atatgtcccg catccgccaa
    13081 caacgccaga gagccggaga gtatcccgcc caccacctca aggagcataa atccggcagt
    13141 gacgataaag gcgaaaagca ggcgacgagc attattatct ttcggcaggt gtgaatcggc
    13201 atgagagtgt gagtgcgcca taacgtcatt cctttgttat tctcatcaat actgtagata
    13261 tcatactgat ttttcgctga caaaataaaa aggagagcga aagctctccc gttatcagac
    13321 ttttttctga attactgcgt ggtaccgtcg gttttggtat tcacgtcatt attgacgcca
    13381 ttaccggttt ccactttttt attaatatcc gggcagcgac catctttaca catggtattt
    13441 ttatgctctt catccttggt cattccgtca tgattcatgg ttgaaccgtc aggatgctgc
    13501 atcgtgctgt tagtattgcc gttggtattg atgtcgttgt tattcacatc attcggcgcc
    13561 acattctggc gggcgtccgg ggcaacctga ccggcatttg ccgccgagtt cgcctggcca
    13621 ttactggact gcgcgttaga ttcagcagct aacgctgcgc cgctggcaag gccgagggta
    13681 gcggtgagta aaagcgtagt cagttttgtc attttcataa gatgctcctg ttatggtgga
    13741 tatgtcggat aacctcttcc aacagtgcac gtgtcagtca aatcctcaaa taagggataa
    13801 aaagcgttcg ccgccgcggg ttaacgcagc agagaatctt gcaataattc ataaacagag
    13861 tggttacagt taaaaagtgt aggttagatc ccattttccg ctacatttgt gcgttttttt
    13921 cctgaattcc aggattattc cgttcaaagt gtaaaagccc gtttacacta tttaattgaa
    13981 gagatagatt ggagggattg cattcattgg gataagtacg gcaacattgg aataaacatg
    14041 aattatcaga atgacgattt acgcattaaa gaaatcaacg agttattacc tccggtcgcg
    14101 ctgctggaaa agtttcccgc cacggaaaat gcagcaaata ccgttgctca cgcacgcaaa
    14161 gccatccata aaattctcaa aggcaatgac gatcgtctgc tggtggtgat cggtccttgt
    14221 tcaattcatg atccggcagc ggcgaaagag tatgccgccc gtttgctggc gctacgcgat
    14281 gagcttcaag gcgagcttga aattgtcatg cgcgtctatt ttgagaaacc gcgtactacc
    14341 gtcggctgga aagggctgat taacgatccg cacatggata acagcttcca gattaacgac
    14401 ggtctgcgta ttgcgcgcaa actgctgctg gatattaacg acagcggcct gcctgccgcc
    14461 ggcgaattcc tcgatatgat cacgccgcaa tatctggccg atctgatgag ctggggcgcc
    14521 attggcgcac ggactactga atcccaggtt catcgcgaac tggcgtctgg cctctcttgt
    14581 ccggtcggtt ttaaaaatgg tactgatggc acgattaaag tcgccattga cgccatcaac
    14641 gccgccggcg cgccgcattg cttcctctcc gtcactaaat ggggtcattc ggcgattgtg
    14701 aataccagcg gcaacggcga ctgccatatc attctgcgcg gcggtaaagc gccaaactat
    14761 agcgcgcaac atgttgctga ggtgaaagaa ggcctcatca aagcgggact gacgccgcag
    14821 gtcatgatcg atttcagcca tgccaactcc tgtaagcaat ttcaaaagca gatggaggtt
    14881 tgcgccgatg tctgtcagca gatagcgggc ggtgaaaaag cgattattgg cgtgatggta
    14941 gagagtcatc tggtagaagg aaaccagagt ctggaaagcg gtcagccgct gacctacggt
    15001 aaaagcatta ctgacgcctg tattggctgg gaagataccg atgcgctgct tcgtcagttg
    15061 tcggcagcgg taaaagcccg tcgaggttaa tcttcattac gtcttaaacc ggcccgcaag
    15121 gccggttttt tactgga
//
LOCUS       DAJVKX010000112        15115 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.112, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000112 DAJVKX010000000
VERSION     DAJVKX010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15115
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.112"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..520
                     /gene="mnmC"
                     /locus_tag="OPY25_003415"
     CDS             <1..520
                     /gene="mnmC"
                     /locus_tag="OPY25_003415"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HCS0928937.1"
                     /translation="LRQVLCYDGYLTPQNPHNQQHCIGASYHRGDESTVWREEDQRQN
                     RQRLLDCFPDANWATEVDVSGNSARCGVRCATRDHLPMVGNVPDYHATLTHYADLADN
                     KTSAASAPVYPGLFMLGALGSRGLCSAPLCAEILAAQMSNEPIPLDAGTLAALNPNRL
                     WVRKLLKGKAVK"
     gene            complement(572..847)
                     /locus_tag="OPY25_003416"
     CDS             complement(572..847)
                     /locus_tag="OPY25_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HCS0928938.1"
                     /translation="MIAEFESRILALIDDMVEHASDDELFASGYLRGHLTLAIAELES
                     GDDHSVEAVYANVSQSLEKAIGAGELSPRDQALVKAMWDNLFDKAKQ"
     gene            complement(880..1429)
                     /locus_tag="OPY25_003417"
                     /pseudo
     CDS             complement(880..1429)
                     /locus_tag="OPY25_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
     gene            complement(1429..2238)
                     /locus_tag="OPY25_003418"
     CDS             complement(1429..2238)
                     /locus_tag="OPY25_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCS0928939.1"
                     /translation="MDNFYDLFMVSPLLLVVLFFVAVLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSLSSSLYFIRRKVVNLAEQKLNILMTFIGSMSGALLVQ
                     HVQADILRQILPILVIFIGLYFLLMPKLGEEDRQRRLYGLPFALIAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGYNLAKSTAHAKVLNATSNVGGLLLFIIGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSARLLYDSHGQEILHWLGMN"
     gene            complement(2238..3062)
                     /gene="mepA"
                     /locus_tag="OPY25_003419"
     CDS             complement(2238..3062)
                     /gene="mepA"
                     /locus_tag="OPY25_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HCS0928940.1"
                     /translation="MKKTAIALLAWFVSSASLAATPWQKITHPVPGAAQSIGSFANGC
                     IIGADTLPVQSDNYQVMRTDQRRYFGHPDLVMFIQRLSHQAQQRGLGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWSQAQLLRPQALDLVSRDGKHVVPSRWSSDI
                     ASLIKLAAQDNDVTRIFVNPAIKQQLCLDAGSDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVL"
     gene            complement(3066..4151)
                     /gene="aroC"
                     /locus_tag="OPY25_003420"
     CDS             complement(3066..4151)
                     /gene="aroC"
                     /locus_tag="OPY25_003420"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCS0928941.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGGIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFDGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWRQVELNPFFCPDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGI
                     LGGISSGQHIVAHMALKPTSSITVPGRTINRMGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRHRAQNADVKTEIPRW"
     gene            complement(4187..5119)
                     /gene="prmB"
                     /locus_tag="OPY25_003421"
     CDS             complement(4187..5119)
                     /gene="prmB"
                     /locus_tag="OPY25_003421"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCS0928942.1"
                     /translation="MDKIFVDEAVSELHTIQDMLRWAVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRINERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNHFAGLISQQPKYILDMCTGSGCIAIACAYAFPDAEVD
                     AVDISPDALAVAEHNIEEHGLIHHVTPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAPDYLSDDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKAQLLAAREHFNIYKD"
     gene            5285..5836
                     /gene="smrB"
                     /locus_tag="OPY25_003422"
     CDS             5285..5836
                     /gene="smrB"
                     /locus_tag="OPY25_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HCS0928943.1"
                     /translation="MKKKTSLSEEDQALFRQLMVGTRKIKQDTIVHRPLRKKITEVPT
                     RRLIQEQADASHYFSDEFQPLLNTEGPVKYVREDVSHFELKKMRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHIFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWQPPELP"
     gene            complement(5885..6370)
                     /gene="sixA"
                     /locus_tag="OPY25_003423"
     CDS             complement(5885..6370)
                     /gene="sixA"
                     /locus_tag="OPY25_003423"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HCS0928944.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTSCGCDESRLMANWLKGQKVD
                     IERVLVSPFLRAEQTLDVVGDCMNLPTQVDVLPELTPCGDVGLVSAYLQALANEEIGS
                     VLVISHLPLVGYLVSELCPGETPPMFTTSAIANVTLDESGKGTFNWQMSPCNLKMAKA
                     I"
     gene            complement(6579..8726)
                     /gene="fadJ"
                     /locus_tag="OPY25_003424"
     CDS             complement(6579..8726)
                     /gene="fadJ"
                     /locus_tag="OPY25_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HCS0928945.1"
                     /translation="MTTTSAFMLSVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILK
                     QIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPV
                     PVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVG
                     VSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERI
                     LAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGEL
                     AMTPQSQALRAVFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLP
                     VRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLV
                     IEAVFEDLPLKQQMVAEVEQNCATHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSP
                     VEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIR
                     MLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVV
                     ASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVM
                     LMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLA
                     ALYGPRYAPCEQLVRMAERREHFWTNGETDQGN"
     gene            complement(8726..10036)
                     /gene="fadI"
                     /locus_tag="OPY25_003425"
     CDS             complement(8726..10036)
                     /gene="fadI"
                     /locus_tag="OPY25_003425"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HCS0928946.1"
                     /translation="MRQALPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARSEIPADAIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKALARVLVDVNKARTTRQRLTLF
                     SRLRLRDLLPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWA
                     EGKLAEEVMTTYVPPYKNPFAEDNNIRGASTLADYAKLRPAFDRKHGSVTAANSTPLT
                     DGAAAVILMTESRAKELGLRPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     ADLTLFDMHEAFAAQTLANLQLLGSERFAREVFGRAQATGEVDDAKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            complement(10214..10498)
                     /locus_tag="OPY25_003426"
     CDS             complement(10214..10498)
                     /locus_tag="OPY25_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HCS0928947.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFATRAEAEETL
                     AALTEKARSVESEPCQITPTFTEESEGVRLDIDFVFACEAETLIFQLGLR"
     gene            10869..12176
                     /gene="fadL"
                     /locus_tag="OPY25_003427"
     CDS             10869..12176
                     /gene="fadL"
                     /locus_tag="OPY25_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416846.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HCS0928948.1"
                     /translation="MSQKTLFTKSALAVAVAIISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSRRTLDADNIAPTA
                     WVPNVHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
                     LNEAWSFGLGFDAVYARAKIERFAGDLGQLVAAQNPALAPVAGQILSDTKIAHLNGNQ
                     WGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLPIAINRFNLPIPTATGGAT
                     QSGYLTLNLPEMWEVSGYNRVAPQWAIHYSLAYTSWSQFQELKAKSTAGDTLFEKHEG
                     FKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTTYAFN
                     KDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF"
     gene            complement(12237..12992)
                     /gene="mlaA"
                     /locus_tag="OPY25_003428"
     CDS             complement(12237..12992)
                     /gene="mlaA"
                     /locus_tag="OPY25_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HCS0928949.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTEQQGRSDPFEGFNRTMYNFNF
                     NVLDPYVVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAIMVNYFLQGDPYQGMVHFTR
                     FFLNTLLGMGGFIDVAGMANPKLQRVEPHRFGSTLGHYGVGYGPYMQLPFYGSFTLRE
                     DGGDMADTLYPVLSWLTWPMSIGKWTIEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGKLKPQENPNAQAIQDELKEIDSE"
     gene            13270..14211
                     /locus_tag="OPY25_003429"
     CDS             13270..14211
                     /locus_tag="OPY25_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCS0928950.1"
                     /translation="MDSLNDDKINRHSSDLEVESEEKQSGKEIEVDEDRLPSRAMAIH
                     EHIRQDGEKEMERDAMALLWSAIAAGLSMGASLLAKGIFHVQLEGVPGGFLLENLGYT
                     FGFIIVIMARQQLFTENTVTAVLPVMQNPTLSNVGLLMRLWGVVLLGNLIGTGVAAWA
                     FEYMPIFDEETRDAFVKIGMEVMKNSPTEMFANAIISGWIIATMVWMFPAAGGAKIVV
                     IILMTWLIALGDTTHIVVGSVEILYLVFNGTLPWSDFFWPFALPTLAGNICGGTFIFA
                     LMSHAQIRNDMSNKRKEEARLRGERLERERKKAEKQR"
     gene            14287..14361
                     /locus_tag="OPY25_003430"
     tRNA            14287..14361
                     /locus_tag="OPY25_003430"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14320..14322,aa:Arg,seq:cct)
     gene            complement(14509..15115)
                     /locus_tag="OPY25_003431"
                     /pseudo
     CDS             complement(14509..15115)
                     /locus_tag="OPY25_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014609409.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3562 a         4234 c         3881 g         3438 t
ORIGIN      
        1 gttgcgtcag gtgttatgct acgacggcta tctgacgccg caaaatccgc ataatcagca
       61 gcactgtatt ggcgccagct atcaccgggg cgacgaaagc accgtctggc gcgaagaaga
      121 tcagcgtcag aaccgacagc gtctgcttga ctgttttccg gatgcgaact gggccacaga
      181 ggttgacgtt agcggcaaca gcgcccgttg cggcgtgcgt tgcgccaccc gcgaccatct
      241 gccgatggtg ggcaatgtcc cggattacca cgccacgctg acgcattacg ccgatttagc
      301 cgataataaa acgtcggcgg cgtctgcgcc tgtgtatccg ggtttattta tgctcggcgc
      361 gctgggatcg cgtggtttgt gttcagcgcc attatgcgca gaaattctgg cggcgcagat
      421 gagtaacgag ccgattccac tggatgccgg tacgctggcg gcgttaaatc caaatcggtt
      481 atgggtgaga aagttattga agggaaaagc ggtgaagtaa tgggccagtc aatagcggaa
      541 ggcggcaagc gtcgccttcc ggtccacggc gttattgttt tgccttgtcg aacaaattgt
      601 cccacatcgc tttgactaac gcctgatcgc gcggcgacag ttcgccggcg ccgatcgctt
      661 tctccagact ttggctaacg ttggcataga ccgcctcaac ggagtggtca tcaccgctct
      721 ccagctcggc aatggctaac gtcaggtggc cacgcaggta tccactggca aaaagctcat
      781 cgtcgctggc gtgctctacc atatcgtcaa ttaatgccag aatgcgtgat tcaaactccg
      841 cgatcatctt ctttcctcat tgtaaacgtg gcgctggctt taattaagcg cttccggcca
      901 cgggaactgt tccgccttaa gttcgggcgt gtgatagtaa ttctgtagcg ctttgatgaa
      961 gcgggccgga cgttcaggaa tgccctgctc cagatacgcc attacctgcg catgaacccg
     1021 gcgctgaaac gccacgcgat ccggctcaat atcgccttcc agattgtcgc aactaacgtt
     1081 taaagggata ccccgccgcc acgcaaaaca accagtcgaa agcctgtggc ttcacctcaa
     1141 cgtcttcaaa ttgactttgg gtctgcgcgt cgcgtccgtc cgggcagtac cagtaaccaa
     1201 agtcgaccag ttcgcggcgc gccttaccgg cgatacacca gtgagaaatc tcatgcagcg
     1261 cgctggcgta aaacccatgc gcaaagacga tacggtggta cggtacctgc gcgtcagcag
     1321 gaagatagat cggttcgtcg tcgcctttaa tcagacgggt attaaattct tcggcaaagc
     1381 agccgttaaa aatctcaatt aattgttcgt aatggtgcgt actgttcatt aattcatccc
     1441 caaccagtgg aggatctcct gtccgtggct atcataaagt aacctggcgc tcatcaccgc
     1501 cgagacaata acgatcatcg gtctgataag cttttggcct ttgctcaaca ccagacgcga
     1561 ccccattcgc gcccctaaaa actgaccaac cagcatcaca aagcccgtcg cccagatcac
     1621 tttgccgccg atgataaata acagcaggcc gccaacgttg gaggtagcgt taagcacttt
     1681 ggcatgtgcc gtggatttcg ccaggttata gccacataag gtgacaaacg ccagagcgta
     1741 aaacgaccct gcggcaggcc cgaaaaagcc gtcgtaaaac ccgacgcatc ccccggctat
     1801 cagcgcgaac ggtaatccat acaggcggcg ctggcgatct tcctcgccca gcttcggcat
     1861 caataaaaaa tagaggccga tgaaaatcac caggatgggc aagatctggc gcaaaatatc
     1921 cgcctgcacg tgctgcacca gcagcgcgcc gctcatcgag ccaatgaacg tcatcagaat
     1981 attgagcttt tgctcggcca ggtttaccac tttacggcga ataaaataga gcgaagacga
     2041 gagggagccg ccgcacgcct gtaatttatt ggtcgccaac gcgtttgccg gcgacatccc
     2101 ggcggccatc agcgcaggga tagtgagcag ccctccgcct ccggcgatag aatcgataaa
     2161 tcctgccagt acggcgacaa aaaacagcac caccagcagc agcggggaga ccataaacag
     2221 atcataaaaa ttgtccatca gagtacatgc tcatccagta gcgcctggca ggaaggcggc
     2281 aacggcggcg gtgtcttctt ctcaggcttt gtggtgccag gttttggcgg ttcgaaccag
     2341 ctttgcagtt cagcgccgca tccatcgccc ggcgggggta aaggttgatc ttcgcactcc
     2401 aggctgtcgg cagggcagcg taaacgcacg tgcatatgcg cgcgatgctg gaaccagggg
     2461 cgtactttac gtagccagtc acgatcgctt ccggcatcga ggcaaagctg ttgtttaata
     2521 gccggattga cgaaaatacg ggtgacgtca ttgtcttgtg ccgccagttt gatcagactg
     2581 gcgatatccg acgaccagcg cgacggcacg acatgtttac cgtcgcggga caccagatct
     2641 aacgcctgcg ggcgcaatag ctgcgcctgg ctccagcgcg ttttcggcaa ctgcaagaaa
     2701 atatccacat caagcccggt ctgatgactg gcgtgtccgc cattaaagcg gcctccggca
     2761 ggcatcccca tgtcgcctat caggacggtt ccgagccccc gttgctgcgc ctgatgactc
     2821 aaccgctgga taaacatgac cagatccggg tggccgaaat aacggcgctg atcggtgcgc
     2881 atcacctgat aattatcgga ctgtaccggc aacgtgtcgg cgccaatgat gcatccgttg
     2941 gcaaagctac cgatagactg ggcggcgccg gggacaggat gggttatttt ctgccacggc
     3001 gtcgccgcca ggctggcgct actgacaaac catgccagca gcgcaatcgc ggtttttttc
     3061 atttcttacc agcgtggaat ctctgtcttt acatccgcat tctgtgcccg atggcgcagc
     3121 aggtgatcca tcagtacgat cgccagcatg gcttctgcga tcggcactgc gcgaatcccc
     3181 acacacggat cgtggcgccc tttggtgatc atctcgacct cttcacccat ccggttgatc
     3241 gtacgtcccg gcacggtaat gctggaggta ggtttcagcg ccatatgcgc cacaatgtgt
     3301 tgcccactac tgatgccacc gaggatgccg ccagcgtggt tgctctgaaa accctgcgcc
     3361 gtgatttcat cgcgattctg gctgccgcgc agcgccacca cgttaaatcc ttcgccgatc
     3421 tccacgcctt tcaccgcatt gatgctcatc agcgcatggg cgatgtccgc atccagtcgg
     3481 tcaaataccg gttcgccaag ccctgccggc acgccgctcg ccatcaccgt cactttcgcg
     3541 ccgatggagt caccctcttt tttcagcgcg cgcatcagtt cgtccagcgc gtcaagtttg
     3601 tccgcatcgg ggcaaaagaa cggattaagc tcaacctgac gccagtcttt aatctccagc
     3661 ggaatgtcgc ccatctgggt caggcagccg cggatttcga tgccgaactt ttccgccaag
     3721 tatttcttgg cgatcgcccc tgccgctacg cgcatcgcgg tttcacgcgc ggaagaacgt
     3781 ccaccgccgc ggtaatcgcg caggccgtat ttctgctcat aggtgtaatc cgcgtgtccc
     3841 gggcgaaaaa catctttaat cgcgctgtag tcctgcgagc gctgatcggt gttttcaatc
     3901 agcaggccaa tactggtgcc ggtcgtcacg ccatcaaaca cgccggagag aatttttacc
     3961 tggtccggtt cgcggcgctg agtagtatag cgcgaggtgc cagggcggcg tctgtcgaga
     4021 tcgtgctgca gatcggcctc cgtcaacggg atgccgggcg gcacgccatc gacgataccc
     4081 ccaagcgcca gcccgtgtga ttcgccgaaa gtggttacgc gaaagagttg tccaattgtg
     4141 tttcctgcca tcacggctcc gttatcgttg ttgtcgtttg cgtgttttaa tctttataaa
     4201 tattgaaatg ttcacgggcc gcgagcaact gcgctttggt caacataaag acgccatcgc
     4261 cgccgttgtc aaactccagc caggtgaacg gcacatccgg atactgctcc atcagatgta
     4321 ccatgctgtt tccgacttca caaatcagaa cgccatcatc ggacagataa tccggcgcat
     4381 ttcccaggat acggcgggtc aatttgaggc cgtcagtgcc ggacgccagc cccagctcag
     4441 gttcgtggcg atattcgttc ggcagatcgg acatatcctc cgcatcgaca taaggcgggt
     4501 tagtgacaat cagatcgtac tgaactttcg gcagatcgcg gaacagatcg gaacggattg
     4561 gcgtcacgtg atggataaga ccgtgttctt caatgttatg ctcggcgaca gccagcgcat
     4621 ccggcgaaat atcgaccgca tcaacctctg cgtccgggaa agcataagca caggcgatgg
     4681 cgatgcagcc gctgccggta cacatatcca gaatatattt cggctgttgg ctaataaggc
     4741 cagcgaagtg gttattaatc agctcgccaa tcggtgaacg cggcaccagc acgcgctcat
     4801 caacataaaa ttcgtggccg cagaaccagg ctttattggt caggtaggct accgggatac
     4861 gctcgttaat gcgacgaatc actcgctcga caatgcggtg tttttcgctg gacgtcagcc
     4921 gcgcggtccg catatcctcc ggaatatcca gcggcagata aagagacggc aacaccagtt
     4981 gtaccgcttc atcccacggg ttatcggtac cgtgtccata ccagatattc gccgcgctaa
     5041 agcggcttac cgcccagcgc aacatgtcct gaatggtatg cagttcactt actgcttcat
     5101 cgacgaaaat tttatccacg tattcctcca gggcatgctc gcattaaatt cggcggctag
     5161 tttgccacga agacagggat aaatcagcat tgacgcggcg ggagaatacg aaaaatccgt
     5221 tttgaccgtt cggatatcct ccgggtcggg taaactaagg caaaagatca gacgagaccc
     5281 acgaatgaaa aagaaaacat cgctcagcga ggaggaccag gcgctgttcc gtcagctgat
     5341 ggtcggcacc cgaaagatta aacaggatac tatcgtccat cggccactgc gcaagaaaat
     5401 cacggaagtc cctacccgaa ggttaattca ggaacaggcg gacgccagcc actatttttc
     5461 tgatgagttc cagccgctgc tcaatacgga agggccggta aagtatgtcc gtgaagatgt
     5521 cagccatttc gagctaaaaa aaatgcgccg cggcgactat tcgccagaac tgtttctgga
     5581 tttacacggc ttaacgcagc ttcaggccaa gcaggaactg ggggcgctga ttgccgcctg
     5641 ccgtcgggaa catatttttt gcgcctgcgt catgcatgga cacggtaaac atattctgaa
     5701 acagcaaacg ccgttatggc tggcgcagca tccgcatgtg atggcctttc atcaggcgcc
     5761 gaaagagtac ggcggcgacg ccgcgctgct ggtgttgatt gaagtggaag agtggcaacc
     5821 gcccgaatta ccctgatgcg gaattgccgg atggcggcgc aagcgcctta tcaggcagca
     5881 aagattaaat cgctttcgcc attttcagat tgcagggact catttgccag ttgaatgtcc
     5941 ccttgccgct ttcatcaagc gtaacgttgg caattgcgga cgtcgtgaac atcggcggcg
     6001 tttcgcccgg acaaagctca gataccaggt atccgaccag aggtaagtga gagatcacca
     6061 gcaccgatcc gatctcttca ttggccagcg cctgaaggta ggcgctgacc agaccgacat
     6121 cgccacaggg cgttagctcc ggcaggacat ccacctgagt cggcagattc atacaatcgc
     6181 cgaccacatc taacgtctgt tcggcccgaa gaaacggact caccagaaca cgttcgatat
     6241 ccactttttg acctttcagc cagttcgcca tcaggcgaga ctcgtcacac ccacaagagg
     6301 tcaagggacg aaccgaatca ctggcggcat cgagggctgc gtcgccgtga cgcatgataa
     6361 aaacttgcat attgcaccgc ttttgttaac cagtttcacc aacacgctta ccacatgccc
     6421 ctattggctg cggcaaaaat gcggtggccg gcattgtgcc ttatccattc accgaatgaa
     6481 acgctgtttt ttacctcaat ggcgtaagta tagtcaatcc ttgattatta tttcgccact
     6541 aaggaggcat tcagtgcgga ttcatattct ctttgacctc aatttccctg gtcagtttcc
     6601 ccattcgtcc agaaatgctc cctgcgctcc gccatgcgca ctaattgttc acaaggcgcg
     6661 taacgaggac cgtaaagtgc ggccaggcgc tgtaatgtcg ccaccatttc acccggcccg
     6721 agagcatcca tatagcggaa cgggccaccg agaaacggcg gaaaaccgat accaaacacg
     6781 gcgccgatat cgccatcgcg cgcgctgcga atcacttttt cgtcgaaaca gcgcgccgct
     6841 tcgttaagca ttaacatgac acagcgctct gccacctgct gcgcagacag tcgactctgc
     6901 ccttgcacgc caataagctt ataaatagca gggtcaacct gttttttgct tttacgccct
     6961 ttttcgccat aaagatagaa accgcgacca ttttttctac ctttgcgatc gtcattcaaa
     7021 attgaagcga caacatttgc aggcgcgcta aaacgttctc catacgccgc ctcaagcaca
     7081 ggaataattt tagtgcccgt gtcgattcct acctcatcca aaagttggat tggccccacc
     7141 ggaaaaccaa attttaccag ggcggcgtca atatgttcga cgcgttcgcc ttcagtcagc
     7201 atccgaatcg cctcattgat atatggcgca agaattcggt taacataaaa cccggcttta
     7261 tcactgacga ctatcggggt tttaccctgt tttttcgcca gcttaacggt cgtggcgatg
     7321 gtctgcgcgg aagtagacgc gtgaggaatg acctcaacca gcggcatttt ttcgaccggg
     7381 ctaaaaaagt gcaatccaat cacctgttcc ggtctggccg cattcgccgc aatatcgcca
     7441 atcggcaggg aagaagtatt ggaggcaaaa atggtgtgag tagcgcaatt ttgctccact
     7501 tccgccacca tctgttgttt taacggcaga tcttcaaaca ccgcttcaat gaccagatca
     7561 cgatgactga aaccacggta atcggtcgaa cctgatatca acgccaactg tttatcgcgt
     7621 tcgctggctt tgatatggcg gcggcgtact tttgtttcaa gcagatccca gctgtatttc
     7681 agagcatgat tgatcccctg agtatttata tccttaattc gtactggcaa accgccttta
     7741 caggccgtaa cccaggcgat accgccgccc attaacccgc cgcctaagat gcccacgctg
     7801 ttcagcgggc cgggcggtgc atcgctaccg ggatcttttt tcacctcggt actggcaaaa
     7861 aaaacagcgc gcagcgcctg cgattgcggc gtcatcgcca gctcgccgaa agcgcgcgct
     7921 tccgcgtcat agccgctact gctgccctgc gccagtccgg tttcaatcac atcaatgatc
     7981 cgctccgtcg ccggataatt accctgcgtt ttttgcgccg tctttttacg caccaggcga
     8041 aataacagcg cgcgccccag cggccccgcc aggatacgtt cacggaccgg taaagtccgc
     8101 tgcgccaggc gttctttttt agccagctcg acagccgctt ccagtaaaat agtttgcggc
     8161 accacatcat caaccagccc ggctttaagc gcctgtctgg cgcgaagctg tttacctgtc
     8221 aggatcatat ccagcgcggt actgaccccc accagccgcg gaagacgctg cgttccgccc
     8281 gatcccggta aaagccctaa ctgtacctcc ggcagtccga gaacggtttt aacgtcatcg
     8341 gtacagatac gccgatggca ggccagcgcc atttcaagac cgccccccag acaggcgccg
     8401 tgaatggcgg cgataaccgg aacaggcaac gcctggatct ccgccatcag ttgttgcccc
     8461 tgacgcgcca gcgtttccgc ttcctgcgcg ttttggcagt ggcctatcat gttgatatca
     8521 gcgccagcaa taaagttatc tgctttggct gagataaaaa caacgccctg caacgcttta
     8581 ttttcccgga tctgcttcag gatggcgcgt acctgcgcgg caaactccgc tttcagggtg
     8641 ttcacctttt ctccagggac atcaatagcg acaaccgcga cattatccag acgcacgcta
     8701 agcataaaag ctgatgtggt agtcattatt ccgcctccag aaccatcgcc gcgccaagac
     8761 cgccagccgc gcaggccgtg accaggccaa aacctccgcc ccgacgccgt aattcatgca
     8821 acgtttgggt tatcatccgc gcgcccgttg cggcaaaagg atgcccgtag gcgattgagc
     8881 cgccgagcac gttgaattta gcgtcatcca cctcccctgt cgcctgcgca cgaccaaaca
     8941 cctcacgggc aaatcgttcg ctgcccagca gttgtaagtt cgccagagtc tgagcggcaa
     9001 acgcttcatg catgtcaaaa agcgtcagat cggccatcgt caacccggcc cgctccagcg
     9061 ccagcggcgt tgaccaggcc ggccccaata gcatgtcctg ccagacatca atagcggtaa
     9121 aggcgtagct gcgcagataa ccaagcgggc gcagccccag ctctttagcg cgggattcgg
     9181 tcatcagaat aacggcggca gcgccgtcgg tcagcggtgt actgttggcg gcggttacgg
     9241 agccatgttt tcggtcaaaa gcgggacgca gtttagcgta gtccgccagc gtggaggcac
     9301 cgcgaatgtt gttgtcttct gcaaaggggt ttttatacgg cggcacatag gtcgtcatca
     9361 cttcttccgc cagtttaccc tccgcccatg cctgcgcggc gcgctgatgt gaacgatgcg
     9421 ccagcgcgtc ctgctgttca cgcgtaatac catacgtttt cgccatctgt tcggcggtat
     9481 cgcccatgcg cagaccggtg gaatactcag caacggcggg aggaacgggc agcaggtcgc
     9541 gtaagcgcag acgagaaaaa agcgtcagcc gttggcgggt cgtccgggct ttattgacat
     9601 caaccagtac ccgcgccagg gctttactca cgcctattgg cagtaccgac gacgaatctg
     9661 cgccgccagc gatacccgcg cgtatcgtgc cggccatcag gctttccgcc acattcgcta
     9721 ccgcctgaaa actggtggcg caggcgcggc ttacgctata ggcatcggta tgaacattca
     9781 ttcccgtacc cagcacaatt tcgcgcgcaa tattgggggc ttccggcatt tgtactacct
     9841 gaccaaaaac cagttgctca atggcatcgg ctggaatttc actgcgcgcc agcagctcgc
     9901 ctaccaccat cttgccgaga tcaacagcgg gaataccatg aaatgcagtg gcctgacgag
     9961 cgaagggggt tcgtaaccca ctgacaatag caatgcgatc gccctgacgg gtgaccaacg
    10021 gtaaagcctg acgcatagta ctcccctgta aaaaaataaa ttagtggtct gacctgatca
    10081 cagtcttaac caatttttta catttagcca agcagagaga aaagaaagtg ggagctaagg
    10141 cacagtgaag ggaaacgaca aaaaaagaaa acgcctccgc cagatgatga cggaggcgtc
    10201 gtgaatgaac ggattaacgc aggccgagct ggaagatcag cgtttctgct tcgcaggcga
    10261 aaacaaaatc aatatccaga cgaacgcctt cggattcctc ggtaaaggtt ggcgtaattt
    10321 ggcaaggttc agactccacg ctacgcgctt tttcggttaa cgccgccagc gtctcttcag
    10381 cctctgcgcg ggtagcgaat acgcggctgt atgacgcggt gcaatcggag ttgtccatga
    10441 tggttccaac gtccatacag cagcaaaccg gggtttcatc agcactgcat ttactcattg
    10501 tagatttcct ctgtatttgc acccagggtg ccagataaac gatggggata ttttacgctc
    10561 ccggcattcg cctctccagt cgttaatggt gggaaacgcg ttaagtgacc gaaatcacac
    10621 ttaaaaatga tctaaaacaa aaatcacgcg atcgggtgac cgttaagccc gccgatttta
    10681 ccagccagat ctcgtttcta agatcacaat tgaaaaaact tataaacata cttgcaacat
    10741 tctagctggt cagacctata ctctcgccac tggtctgatt tctaagtcgt accgcagacc
    10801 ctacacttcg cgctcctgtt acagcatgta acatagtttg tataaaaata atcaatgagg
    10861 ttatggtcat gagccagaaa accctgttta caaagtctgc tctcgcagtc gcagtggcaa
    10921 tcatctccac ccaggcctgg tctgcgggct ttcagttaaa cgaattttct tcctctggcc
    10981 ttggccgggc ctattcgggt gaaggcgcaa tcgcagatga tgcgggtaac gttagccgca
    11041 acccggcgtt aattaccatg tttgaccgcc cgacgttttc agcgggcgca gtttatattg
    11101 atcctgatgt taatattagc gggacatcgc catctcgtcg gacgttagat gcggataaca
    11161 tcgcgccgac ggcctgggtg ccgaacgtcc attttgtcgc cccgattaac gaccagtttg
    11221 gctggggggc ttctattacc tctaactatg gtctggcgac agagtttaac gacacatacg
    11281 ccggcggctc ggttggcggt acgaccgatc ttgaaaccat gaacctgaat ttaagcggcg
    11341 cttatcgctt aaatgaggcc tggagcttcg gcctcggctt tgatgcggta tacgcgcgcg
    11401 cgaaaatcga acgttttgcg ggcgatttag gccagttggt cgcggcacag aatccggcgc
    11461 tggcgccggt cgcgggtcag attctcagcg acaccaagat tgcccacctg aacggtaatc
    11521 agtggggctt tggctggaat gccggtatcc tttatgaact ggataaaaat aaccgctacg
    11581 cgctgaccta ccgctcggaa gtcaaaattg actttaaagg caactacagt agcgatcttc
    11641 ccatcgctat aaaccgattt aacctgccta tcccaacggc aaccggcggc gcgacgcagt
    11701 caggctacct gacgctgaat ctgccggaaa tgtgggaagt gtccggttat aaccgtgtgg
    11761 cgccacagtg ggccatccac tatagcctgg cctataccag ctggagtcag ttccaggaat
    11821 tgaaggcaaa atcgaccgcc ggcgatacgc tctttgagaa gcatgaaggc tttaaagacg
    11881 cttatcgcat tgcgttgggt accacctatt actacgatga caactggacg ttccgtaccg
    11941 gtatcgcctt cgatgacagc ccggtaccag cgcaaaaccg ttctatctct attccggatc
    12001 aggaccgttt ctggctgagc gccggtacga cttacgcctt taacaaagat gcgtctgtcg
    12061 acgttggcgt ctcttatatg catggtcaga gcgtgaaaat taatgaaggc ccttatcagt
    12121 ttgaatctga agggaaagcc tggctgttcg gtactaactt taactacgcg ttctaatctc
    12181 tttctgaaac ggatcaaaaa ggtgagcatt gcgctcacct ttttatttac tgccgtttat
    12241 tccgagtcga tctctttgag ttcgtcctga atcgcttgcg cgttcgggtt ttcctgcggc
    12301 ttgagttttc cgccattggc gataaagtca tgacgctgga agtatgcctc gcgcaccata
    12361 atataaggat cggaagactg gcgcagcaaa ccatcggagt ccagcaactg cgcgcgggtt
    12421 tctatccctt cgatagtcca ttttcctatg gacattggcc aggtcaacca cgagagcacc
    12481 ggatacaagg tatccgccat atccccgcca tcttcacgca gcgtgaagct gccgtagaac
    12541 ggaagttgca tataaggccc ataccccacg ccataatggc ccagtgtact gccaaagcga
    12601 tgcggttcaa cgcgctgcag cttaggattc gccattcccg cgacgtcaat aaagccgccc
    12661 atccctaata aggtattcag gaagaaacgg gtgaaatgca ccataccctg ataaggatcg
    12721 ccctgcagga aatagttcac catgatcgcc ggttcttcga ggttgccggt gaaattactt
    12781 aaaccgttac gcgcaggctg tggaacataa tcacgccagg cgaccgcgac cggccgaaca
    12841 acatacgggt ccagcacatt aaagttgaag ttgtacatgg tgcggttaaa cccttcaaat
    12901 gggtctgaac gcccctgctg ttctgtaccg gaactcgcac acccgaccag cagtgtggtt
    12961 cccagcgcca gcgccgacag gcgaagcttc atagatgtct ccctgtgaat tatggctatc
    13021 gctgattgcc atccatgacg gaacgctacc gtatcctgtg agcgatttta acagcacgtc
    13081 aaacgatgtc tatatgcgcg atctcattgc tctgagcata gcctggtaac gcaacaacat
    13141 gacggcccta ttctaacgaa acagataaaa acgagcgtga ttatttttat tttttcggag
    13201 aatgccccgg cctgggtaaa tgaaaaaccg ctacgcttta ttaatatgtg ttaatcagca
    13261 aggatcatca tggatagcct taacgacgat aaaattaacc ggcacagcag tgacctggaa
    13321 gttgaaagcg aagaaaaaca aagcggtaaa gagattgaag tagatgaaga tcgtcttcct
    13381 tcccgcgcca tggcgattca tgaacatatt cgccaggatg gtgaaaaaga gatggaacgc
    13441 gatgcgatgg ctttgctctg gtcagccatt gccgcaggac tttctatggg ggcatcactc
    13501 ctggcgaaag ggattttcca cgtgcagctt gaaggcgttc ccggcggctt tttactggaa
    13561 aatctcggtt atacctttgg ttttatcatt gtcatcatgg cccgccagca attatttact
    13621 gaaaataccg ttaccgccgt attgccggta atgcaaaatc ccacgctgag taacgttggc
    13681 ctgctgatgc gcttatgggg cgtagtctta ttgggcaacc ttattggcac cggggttgcg
    13741 gcgtgggctt ttgaatatat gcctatattt gatgaagaga cccgcgatgc ctttgtcaaa
    13801 attggtatgg aggtcatgaa aaatagccca acggagatgt ttgccaacgc gattatctct
    13861 ggctggatca tcgccacaat ggtatggatg tttcctgctg caggcggggc aaaaattgtg
    13921 gtcattattt tgatgacctg gcttatcgcg ctgggcgata ccacccatat tgtcgtcggt
    13981 tccgttgaaa ttttgtattt ggttttcaac ggcacgctgc cctggagcga ctttttctgg
    14041 cccttcgccc ttcccacact tgccggaaat atctgcggcg gcacctttat tttcgcattg
    14101 atgagccacg cgcagatccg caacgatatg agcaataagc gtaaggaaga agcgaggcta
    14161 cgcggcgagc gcctggaacg ggagcggaaa aaagcggaaa aacagcgctg agtggcgacg
    14221 gtttaaccag tcaggcggcg ctacacttac tccggcgaat aaaaaacgct atactggcgc
    14281 cgcgttgtcc ccttagttaa atggatataa cgagcccctc ctaagggcta gttgcaggtt
    14341 cgattcctgc aggggacacc atgacctctt ttacccacct ctcacgaatc tcagcaaacc
    14401 cacaccacac aaggcgttgc agcgtttttg atgtcttatg atctccagcg aatagtgcct
    14461 ataaacataa cgaaaagcat ccctttaaag tcccctctcg ctgttagaac ttaaccaaaa
    14521 gttagcacct tcactttccg acagatatag gcccagaact tcttttttgc cttctagatt
    14581 cagtgccaga acggtataaa ccgccttgct ctgataacgg ccatcctcac ggtttttata
    14641 atgaatagcg tccagccaga cgacgggata aaccttctcc agcgggctct gttgccactg
    14701 ttttagttca gggatgactt tatcggtact gcactgacgg tggcggttga aacgctgaag
    14761 gcataaagat cttcactctc ccggccgatg tcctgataac tcatctccag cgcaaacagt
    14821 cgaatgatat tgcgctcgat ctcgtcgtac agggggtctg aagcttcttc accaattatg
    14881 gctcaaaagt gccgttacga ttgcgcggag ttgccagttc aaaactgcct gttggggctt
    14941 taatggcttt ttgccggaac catttttacg gtttgcctca acatcctgag ccagatggga
    15001 atcaagttca gcagacaggg tagagtcggt taaatacttg attaatggcg ttaagatgcc
    15061 atctttgccc gttaatgcct ggccggacct gaagggcttt aagtgctttg tcgaa
//
LOCUS       DAJVKX010000113        15076 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.113, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000113 DAJVKX010000000
VERSION     DAJVKX010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15076
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.113"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(268..1458)
                     /gene="glpC"
                     /locus_tag="OPY25_003432"
     CDS             complement(268..1458)
                     /gene="glpC"
                     /locus_tag="OPY25_003432"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HCS0928951.1"
                     /translation="MSDTRFESCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFILSHTDLMG
                     SVSTPFAPVVNTATALKPVRQLLDYALKIDHRRTLPKYSFGTFRRWYRSVAAQQAKYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AISNVESLREAIAVKGIPVIATSSTCTFALRDEYPEVLDVDNAGLREHIELATRWLWR
                     KLDAGKTLPLNPLPLKVVYHTPCHMEKMGWTLYTLELLRQIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQSIGAPLFRQIEESGADIVVTDCETCKWQIEMSTSKRCEYPITLLA
                     KALG"
     gene            complement(1455..2714)
                     /gene="glpB"
                     /locus_tag="OPY25_003433"
     CDS             complement(1455..2714)
                     /gene="glpB"
                     /locus_tag="OPY25_003433"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HCS0928952.1"
                     /translation="MKFDTVIMGGGLAGLLCGLQLQQHGLRCAIVTRGQSALHFSSGS
                     LDLLSALPNGQPVTDITAGLDALRRQAPEHPYSRLGAQKVLTLAQQAQTLLNASGAQL
                     YGDVQQAHQRVTPLGTLRSTWLSSPEVPVWPLSAQRICVVGVSGLLDFQAHLAAASLR
                     QRDLNVETAEIDLPELDVLRDNPTEFRAVNIARLLDNEEKWQLLYDALSPIATNCDMI
                     IMPACFGLANDTLWRWLNERLPCALTLLPTLPPSVLGIRLHNQLQRQFVRQGGIWMPG
                     DEVKKVTCRRGTVSEIWTRNHADIPLRPRFAVLASGSFFSSGLVAEREGIREPILGLD
                     VQQTATRAEWYQQHFFDPQPWQQFGVVTDDAFRPSLAGNTVENLYAIGSVLAGFDPIA
                     EGCGGGVCAVSALQAAHHIAERAGEQQ"
     gene            complement(2704..4332)
                     /gene="glpA"
                     /locus_tag="OPY25_003434"
     CDS             complement(2704..4332)
                     /gene="glpA"
                     /locus_tag="OPY25_003434"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HCS0928953.1"
                     /translation="MKTRDSQASDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTDGLFITLPEDGLA
                     FQATFIRACEAAGIRAEAIDPQQARIIEPSVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AREHGAIVLTAHEVTGLIREGATVCGVHVRNHLTGETQTLHAPVVVNAAGIWGQRIAE
                     YADLSIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSTHIDYN
                     EIDSNRVTADEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LFDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCITADTPLPGSKES
                     TEHTLKRIISLPAPLRGSAVYRHGDRTPGWLSEGRQHRSLVCECEAVTAGEVQYAVEN
                     LTVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTAAQSITQLSEFLNERWKG
                     VQPVAWGDALRESEFTRWVYQGLCGLEKEHQDEI"
     gene            4565..5923
                     /gene="glpT"
                     /locus_tag="OPY25_003435"
     CDS             4565..5923
                     /gene="glpT"
                     /locus_tag="OPY25_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HCS0928954.1"
                     /translation="MLSIFKPALHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPSCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWKAALYMPAFGAIVVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEEELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGASGVFFMTLVTI
                     ATIVYWMNPAGNPNVDMACMIIIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLVVVMIGEKRHHDELQLKRN
                     GG"
     gene            5928..6998
                     /gene="glpQ"
                     /locus_tag="OPY25_003436"
     CDS             5928..6998
                     /gene="glpQ"
                     /locus_tag="OPY25_003436"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCS0928955.1"
                     /translation="MKTTLKNLSVALMLAGMTIGSGAVAAEKVVIAHRGASGYLPEHT
                     LPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAI
                     DFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRIHTFEEEIEFVQGLNHSTG
                     KNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYIGKQDNVYLQCFDVAELKRIKNE
                     LEPKMGMDLNLVQLIAYTDWNETQQKQPDGRWVNYNYDWMFKPGAMKQVAEYADGIGP
                     DYHMLVAEGSTKGNIKLTGMVQDAHQNKMVVHPYTVRADQLPDYATDVNQLYDILYNK
                     AGVDGLFTDFPDKAVMFLQKND"
     gene            complement(7114..7992)
                     /locus_tag="OPY25_003437"
     CDS             complement(7114..7992)
                     /locus_tag="OPY25_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0928956.1"
                     /translation="MTLTQIHALLAVLEYGGFTEASKRLYMTQSAVSQAISALEEELG
                     VDILIRERRKEIELTAAGSRIVRHLRAIQRDVNAVKEIVEQEKKNPARTLRIGCFPSA
                     CACILPGVIRYFESHHPNVKIIPYEENSTAIIDSLQDGSIDAGFVPFPVNGMYCVPIY
                     RDKFTVVVPENHPLAANSTVTVEELMDEPLIVSKGRYELSIMALFKEKGIEPIFKYEF
                     NHPDTALNFIRQGLGIALLPELTLKATTGKLCSVALEPTFYRQISLLAKEPPVEGSPL
                     FLLQKCMETLTDEGLL"
     gene            8154..9344
                     /locus_tag="OPY25_003438"
     CDS             8154..9344
                     /locus_tag="OPY25_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928957.1"
                     /translation="MKEKLWTKDFWAITIVSFIIFFVFYVLLTLLPIYIADRLHASAD
                     KAGLLVTCFLAAAIVIRPFAGQWVGKYSNKKILVLSSLAFLVITALYPVCHSIESLLF
                     IRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWD
                     AFTAAFWLCSAVAALGIVLSLIVTVPPVIRHADGSKPNLGFSAMFDRAALPFALVTFF
                     MTFSYAGVSAFLALYARELDLMAAASNFLLCYAILLMICRTFTGNICDKKGPKYVVYP
                     CLLAFTIGLVALGYTNGSIMMIISGGLIGIGYGSVTPVFQTQIISSVEPHKIGVANSL
                     FFNAMDAGMAIGAFIMGMMVESVGYRMIYVAGAVLVVLAGALYAVQMKKRGVMPLVST
                     SELH"
     gene            complement(9346..9600)
                     /gene="yfaE"
                     /locus_tag="OPY25_003439"
     CDS             complement(9346..9600)
                     /gene="yfaE"
                     /locus_tag="OPY25_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HCS0928958.1"
                     /translation="MGRVTLRITGTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGS
                     CRTRLVAGQVDWITEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(9600..10730)
                     /gene="nrdB"
                     /locus_tag="OPY25_003440"
     CDS             complement(9600..10730)
                     /gene="nrdB"
                     /locus_tag="OPY25_003440"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HCS0928959.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPAVVFDDIVTNEQIQKRAEGISAYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVVVNLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGVDDPEMAEIAEECKQECYDL
                     FVQAAQQEKEWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL"
     gene            complement(10843..13128)
                     /gene="nrdA"
                     /locus_tag="OPY25_003441"
     CDS             complement(10843..13128)
                     /gene="nrdA"
                     /locus_tag="OPY25_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HCS0928960.1"
                     /translation="MNQSLLVTKRDGRTERINLDKIHRVLDWAAEGLNNVSVSQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAFGQFEPPAL
                     YHHVVKMVELGKYDNHLLEDYTEEEFKQMDSFIVHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVVACLFSNYPRETRLDYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGIQINKLMYTRLLKGGDITLFSPSDVPGLYDAFFADQDEFERLYVKYENDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPVVAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAIKTLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYWLAKNGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDAIVNEPLHYDWEQLRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLKDAYELLWEMPNNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLAPSIQDDGCESGACKI"
     gene            complement(13483..14211)
                     /locus_tag="OPY25_003442"
     CDS             complement(13483..14211)
                     /locus_tag="OPY25_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HCS0928961.1"
                     /translation="MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLR
                     LGYITERSGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNP
                     ITNTFKLGPGVDVNYMLHTRAKKA"
     gene            complement(14294..14989)
                     /locus_tag="OPY25_003443"
     CDS             complement(14294..14989)
                     /locus_tag="OPY25_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0928962.1"
                     /translation="MKNRLKRDFSHISIEIPKSITQVIKEKIREMIIHGDFDLGQAIS
                     ENELSNILMISKTPIREAFIWLSYNENLVNIIPRSGTFVFSVTDEDINDLIKMRVILE
                     QGAIREAMEKNANNVIVELSNILSKSAKINAERDTQAYLKLDHDFHYVFVKYADNKYI
                     SQAHLLISARLLAIRYRLDFTAEYITSSNRGHATILDMLKNNNVEGVCNFITHHIGSG
                     FTERARKLLALKA"
BASE COUNT         3417 a         3802 c         4033 g         3824 t
ORIGIN      
        1 tccccctctt taaaggaggc tggtaacgcg gcgatacaag agatattgct ctataaacag
       61 taacgtcgtt atctgtcatg ccaccgtggg ttagcggtca tggttaacca aatagggcag
      121 gttattgcaa agagacatcc gcgtttatac ccaaaataat ccgtagccaa cacataagca
      181 acttgaagta tgaagggtat atgtctgatg gaaaatcggc cctggtgagt agagtaatgg
      241 cgccggaggg gctccggcgc tttttactta gcccagcgct ttcgccagta gcgtaatggg
      301 gtattcgcag cgtttgcttg tagacatctc aatttgccac ttacaggttt cacaatcggt
      361 gacgacaatg tcggcgccgc tctcttcaat ctggcggaac agcggcgcgc cgatggactg
      421 tgatgtcgga tagttttcct ttttaaatcc atacgtaccg gcaatgccgc agcactgtga
      481 atcaagtacc gtcaattcaa gccccggaat ttgccgcaac agttcaagcg tgtaaagcgt
      541 ccagcccatt ttttccatat gacacggcgt atggtagacc actttcagcg gcaaaggatt
      601 aagcggcagc gttttcccgg catccagttt gcgccatagc cagcgggtgg ccagctcgat
      661 atgttcgcgc agcccggcgt tgtccacgtc cagcacttca ggatattcat cgcgcaacgc
      721 aaacgtacag gtggatgacg tggcgatgac cggaatacct ttgacggcaa tcgcctctcg
      781 tagcgactcc acattgctga tagcctgttt gcgagcttta tccgtaaaac cgttagcgat
      841 cagcggtacg ccgcaacact tctctttact cagtaactgt acgccagtac ccattgcgtt
      901 cagcacctta atcagatctt ttccgagctg cggatggttg taattcacaa aacagccatg
      961 gaaaaaggcg acctgatctt tgtatttagc ctgctgcgcc gccacgctac gataccagcg
     1021 gcggaaggtg ccgaaagagt attttggtaa ggtgcggcga tgatcgattt tgagcgcgta
     1081 atcaagcaac tggcgcactg gctttaatgc ggtggcggta ttgaccaccg gcgcgaacgg
     1141 cgttgaaacg ctgcccatca gatcggtatg gctgagaata aagttacgca atgacgggcg
     1201 cgtcgtatcg tatttcgcgc gggcgcgctg gatgatatcg ccaatcttca cgtccgacgg
     1261 acaggcgacc tcacaccgtt tgcagttaat gcaatatttc agcgcctcat catacagcgc
     1321 gccgtctttc agacgcaggc gttcgccatc cggtccggcc tgtttagggc cagggtagcc
     1381 aggattaacg cggctgaccg ggcacgcggt ggtgcacacc gtacatttaa tacaactttc
     1441 aaaacgtgtg tcgctcattg ctgttctcct gcacgctcag cgatatggtg cgcggcctgg
     1501 agggcgctga ctgcgcagac gccgccgccg catccctcag ctataggatc gaatcccgcc
     1561 agcacagaac ctattgcata cagattttct accgtgttgc ccgcaaggga ggggcggaaa
     1621 gcgtcatccg tcacgacgcc aaactgctgc cagggctgtg ggtcgaagaa atgttgttga
     1681 taccattcgg cgcgggtggc cgtttgctgt acgtcgagcc ctaaaatagg ttcgcggatc
     1741 ccttcgcgct cggcaaccag cccgctacta aagaagctac cgctggcaag tacggcaaaa
     1801 cgcgggcgca gtgggatatc ggcatggttg cgggtccata tttcgctcac ggtaccgcga
     1861 cggcaggtga ctttcttcac ttcatcgccc ggcatccaga tgccgccctg acggacaaac
     1921 tggcgctgga gttgattgtg cagacgaata ccgagcaccg atggcggcag cgtcggcagc
     1981 agcgtgagcg cgcagggcag acgttcgtta agccagcgcc acagcgtatc gttcgccagc
     2041 ccgaaacagg cgggcatgat gatcatgtcg cagtttgtcg ctattggcga cagcgcgtcg
     2101 tacagcagct gccatttttc ttcgttatca agcagacgcg cgatattgac cgcgcgaaat
     2161 tccgtcgggt tatcacgcag tacgtccagt tccggaaggt cgatttctgc ggtttcaacg
     2221 ttgaggtcgc gttggcgcag cgacgctgcc gcaaggtgcg cctggaaatc cagtaatccg
     2281 ctaacgccga cgacgcaaat tcgctgtgcg gataacggcc agaccggtac ttccggcgag
     2341 ctaagccagg tagaacgcaa tgtgccaagc ggcgtgacac gctggtgcgc ctgctgtacg
     2401 tcgccgtata actgcgcgcc gctggcgtta agtagcgttt gcgcctgttg cgccagcgta
     2461 aggacttttt gcgcgcctaa acgcgaataa ggatgttcag gcgcctggcg gcgcagcgca
     2521 tcaagcccgg cggtaatgtc ggtcaccggt tggccgttgg gcagggcgct aagtagatcc
     2581 agcgagccgg aggaaaaatg cagcgcgctt tgtccgcggg tgacgatggc gcagcgtaat
     2641 ccatgctgct ggagttgcag tccgcatagc aaaccggcga gaccgccgcc cataataacc
     2701 gtatcaaatt tcatcctggt gctccttctc cagaccgcat aatccctgat aaacccagcg
     2761 cgtgaattcg ctttcgcgca gcgcgtctcc ccaggcgaca ggttgtacgc ctttccagcg
     2821 ctcattcaga aattcagaga gttgcgtaat agattgcgcc gcggtcgtca cattaaaacg
     2881 ctgcaatagc ccggccgcgc ggcaggcgca cagttcgccc tggcaagtgc ccatccctac
     2941 gcgggtgcga cggcgcagat ccagcaggct attcacggtt aagttttcga cggcatactg
     3001 cacttccccc gccgtgacgg cctcgcattc acagaccagg ctacggtgtt ggcggccttc
     3061 actcagccac cccggcgtgc gatcgccatg ccgataaacc gccgatccgc gtagcggcgc
     3121 gggaagcgag ataatgcgtt tcagcgtatg ttccgtagac tcttttgagc caggcaacgg
     3181 cgtatccgcc gtgatgcagg ggcgagtatt gcccaacttg cggcacacgg cgtcggtcgc
     3241 ccattccgcc atcaggcgat aagtcattag cttcccgccg gtaatggtaa tgaagccatc
     3301 aagcccgtcg cgttcggcgt ggtcgaacaa cacaataccg cggctgacgt tacgaccgct
     3361 gggatcgtca tcgctggcca ccagcgggcg gacgccggaa tacgcgcgca gaatacgtgt
     3421 cttcgccatg acaggggcca gtttttcccc ttcacgcagc aggatatcga cttcatctgc
     3481 ggtgacgcgg ttgctgtcta tctcattgta atcaatatgg gtagaggtgg tgccgatcag
     3541 tgaaatcgta tcgccaggta ccagaatgtc ggcatccgat ggtttccggc agcggttaat
     3601 gacatgctgg ttgatccgat ggtccatgat caacagcgag cctttcgccg ggaacatgcg
     3661 aatactcagg tcggcgtatt cggcgatccg ttgcccccag ataccagccg cattgaccac
     3721 caccggcgcg tgaagcgtct gggtttcgcc agtgagatgg ttacgcacat ggacgccgca
     3781 gaccgttgcg ccttcacgaa tgagcccggt cacttcatgc gccgttaaca cgattgcgcc
     3841 atgttctctg gcatccagca tattggcggc ggtcaggcgg aaagggtcta cggtgccatc
     3901 cggcactttt accgcaccga tgagcgcagg gttaacggaa ggttcgatga tgcgagcctg
     3961 ctgcggatcg atggcttcag cgcgaatgcc tgccgcttca caggcgcgaa taaaggtggc
     4021 ctgaaacgca agaccatctt ccggcaacgt aataaacaga ccatccgtcg gttcgacgca
     4081 atggcgggcg atccgtttta aaatctggtt ttcactaatg cactcgcgcg cggattccgc
     4141 gtcggtaacc gcataacgag cgccgctgtg cagcagcccg tggttacgcc cggtcgcgcc
     4201 ggtcgctata tcatgccgct ccaccagaat gacacgtaaa ccgcgcagcg cgcagtcgcg
     4261 ggcgatccct gcgcctgttg ctccaccgcc aatgataatc acgtcacttg cttgcgagtc
     4321 gcgagttttc attgtttttc cttacagttc gttttttatc atttagccat acaaatcata
     4381 tggaatgttt gatttcgcgc gcctttctga acattagtca taaaactgta acaatatgtg
     4441 ctgtaattca cattaacgtg acgtatcttt acttaacatc gcggccacac tgggagcagc
     4501 ggggttgttt gaacgaactg cggtgtttac ctctaaataa aatacgggct acggaggcta
     4561 caatatgttg agtattttta aaccagcgct tcataaagcg cgcttgccag cggcggagat
     4621 tgatccgacc tatcgccgat tacgctggca gattttcctg gggatattct ttggctatgc
     4681 cgcgtattat ctggtgcgca agaactttgc cctcgcgatg ccctacctgg tagaacaggg
     4741 tttttcacgc ggcgatctgg gctttgcgct gtccgggatt tctatcgctt atggtttttc
     4801 gaaatttata atgggttcgg tgtccgatcg ctcgaatccg cgcgtttttc tgccggcagg
     4861 gttgattctg gccgcagcag tcatgttgtt tatgggcttt gtgccgtggg cgacatccag
     4921 catcgccgtg atgtttgtgc tgttgttcct ttgcggctgg ttccagggga tggggtggcc
     4981 gtcgtgcgga cgtacgatgg ttcactggtg gtcgcagaaa gagcgcggcg gcattgtgtc
     5041 ggtctggaac tgtgcgcata acgtcggcgg cgggatcccg ccactgctgt tcctgctggg
     5101 gatggcgtgg tttaacgact ggaaagcggc gctctatatg ccagcctttg gcgcgattgt
     5161 ggtggcactg ttcgctttcg caatgatgcg cgatacgccg caatcctgcg gtctgccgcc
     5221 tatcgaagag tataaaaacg actatccgga tgactacaac gaaaaagcgg aagaagagct
     5281 gactgcgaag cagatcttca tgcagtacgt actgccgaac aaattactgt ggtatatcgc
     5341 tatcgccaac gtgttcgtct acctgctgcg ctacggtatc ctcgactggt caccgaccta
     5401 cctgaaagaa gtgaagcatt tcgcactcga taaatcctcc tgggcctact tcctctatga
     5461 atacgcgggt attccaggca cgctgctgtg tggctggatg tcggataaag tcttccgcgg
     5521 caaccgtggc gcgtcgggcg tattctttat gaccctggtc actatcgcga ccatcgttta
     5581 ctggatgaac ccggcaggca acccgaacgt tgatatggct tgtatgatta tcatcggctt
     5641 cctgatctac ggcccggtaa tgttgatcgg tctgcacgcg ctggagctgg cgccgaaaaa
     5701 agcggcgggt acggcggcgg gctttaccgg tctgtttggt tacctgggcg gttctgtcgc
     5761 tgcaagcgcc attgtgggtt ataccgttga cttcttcggt tgggatggcg gctttatggt
     5821 gatgattggc ggtagcattc tggcggtaat cctgctggtg gtcgtgatga ttggcgaaaa
     5881 acgccatcat gatgagctgc agttaaaacg caacggaggc taataacatg aaaaccacac
     5941 tgaaaaacct tagcgtggcg ttgatgttgg caggaatgac catcggaagc ggcgccgtgg
     6001 cggctgaaaa agtcgtcatc gcccaccgtg gcgccagcgg ttatctgccg gagcatacgc
     6061 taccggcgaa agcgatggcg tatgcgcaag gggcagatta tctggaacag gatttagtga
     6121 tgacaaagga cgaccatctg gtcgtcctcc atgaccacta ccttgaccgg gtgactgacg
     6181 tcgctgatcg ttttccggac cgggcgcgta aagatgggcg ctattacgct atcgatttta
     6241 cgctggatga aattaaatcc ctgaagttta ccgaagggtt tgatattgaa aacggcaaaa
     6301 aagtacaaac ttatccgggc cgtttcccga tgggaaaatc tgatttccgc attcatacct
     6361 ttgaagagga aattgaattc gttcagggat taaatcactc taccggtaaa aatatcggta
     6421 tttatccgga aattaaagca ccgtggttcc atcatcagga agggaaagat attgccgcga
     6481 aaacgctgga agtgctgaag aagtatggtt acatcggcaa gcaggacaat gtctatttgc
     6541 agtgttttga tgtcgctgag ctgaaacgta ttaagaatga actggaaccc aaaatgggga
     6601 tggatctcaa tctggttcaa cttattgcgt ataccgactg gaatgaaacc cagcagaaac
     6661 agccggacgg tcgttgggta aattacaact acgactggat gtttaagccg ggcgctatga
     6721 agcaggtggc ggaatatgcg gacggtattg gtccggatta ccacatgttg gtcgcggaag
     6781 gttcgacgaa agggaatatc aagctgactg gaatggtgca ggacgcgcat cagaataaga
     6841 tggtagtgca tccttacact gtgcgtgccg atcaattgcc ggactatgcc acagacgtca
     6901 atcagttata cgatatcctg tataacaagg cgggcgtcga cgggctgttc accgacttcc
     6961 cggataaggc ggtcatgttt ctgcaaaaaa atgactaaag gtatgccata gtagaagtga
     7021 agcgccggat gaggacataa acgcctcatc cggcctggcg caacgtttgc cagcgtaagt
     7081 ctgataaacg caatgtcatc aggcggtgtt gttttatagc aaaccctcat cggtcagtgt
     7141 ttccatacat ttttgtaata aaaatagcgg gcttccttct accggcggtt cttttgctaa
     7201 cagtgaaatt tgtcgataaa aggtgggttc cagcgccacg gagcataatt ttcctgtcgt
     7261 ggcttttaag gttaattctg gcaataaggc gatacctaat ccctggcgaa taaaattcag
     7321 cgcagtatcg ggatggttaa attcatattt aaatatcggt tcaataccct tttctttaaa
     7381 caacgccata atacttaatt cataacgacc tttactgaca ataagtggtt cgtccatcag
     7441 ttcttcgacc gttactgtac tattggccgc caggggatga ttttcaggca ccactacggt
     7501 gaatttatcc cggtaaatgg ggacgcaata cataccgttg accggaaaag gaacgaaacc
     7561 ggcatcaata cttccgtcct gcagcgaatc aataatagcc gtactgttct cttcataggg
     7621 gataattttt acatttggat gatggctttc aaaatagcga atgacgccgg gtaaaatgca
     7681 ggcgcaggcg ctgggaaaac agccaatccg tagcgtacgg gccgggttct ttttttcttg
     7741 ttcgacaatc tcttttaccg cgttgacgtc gcgctggatc gcgcgtaagt gcctgacgat
     7801 gcggctaccg gcggcggtaa gctcgatctc tttacgacgc tcacgaatca atatgtcaac
     7861 gccgagctcc tcctcaagcg cggagatggc ctggctgacg gcggattgcg tcatgtatag
     7921 ccgtttgctg gcctcggtaa atccgccgta ctccagtacg gcaagcaggg catggatttg
     7981 ggttagcgtc attagtaaaa cctaatcaat ataattaaaa cgattaattt ttctaataaa
     8041 gtgcacttgt ttatactgcg attctatcga atacatcaca ttttgacgca cctgataggt
     8101 gttcagttga gctgagcgtt gcctgcgtgc gccatctgaa tgggtcgtta agaatgaaag
     8161 aaaaattatg gacgaaggat ttttgggcaa tcaccatagt aagttttatt atcttttttg
     8221 ttttttatgt actgctaact ttattaccca tttatatcgc tgaccgcctg catgcttctg
     8281 cagataaggc aggattgcta gtgacatgtt tcctggccgc ggcaattgtt attcggccgt
     8341 ttgccgggca gtgggtggga aaatattcga ataaaaagat tctggtgctc tcttctctgg
     8401 cttttttggt gattaccgcg ctgtatccag tttgccattc tatcgagtcg ctgctcttta
     8461 tccgcgtact tcatgggatt acgtttggtg ttattaccac ggtaaaagga actatttcag
     8521 cgcggttaat tccggcctcc cgacgtggag agggcatcag ctttttctct ttagcgatgg
     8581 gcctggcgat ggtcgtagga ccgtggattg gtttgaatat ggcccgctgg gacgcgttca
     8641 ctgccgcatt ctggctttgt tccgctgtag cggcgttagg gattgtgctt tccctgattg
     8701 tgacggttcc tccggtaatt cgtcatgccg atggttcgaa accgaatctg ggtttttccg
     8761 cgatgtttga ccgcgccgcc ttgccttttg cgctggtcac cttttttatg actttctcct
     8821 atgccggcgt gtcggctttc ctggcgctgt atgctcgtga gctggattta atggcggcgg
     8881 ccagtaattt cctgctgtgc tacgcgattt tactgatgat atgccgtacc ttcaccggga
     8941 atatttgtga taaaaaaggg ccgaaatatg ttgtttatcc atgtctgttg gcttttacca
     9001 tcggtctggt ggcgctgggc tacaccaatg gcagcatcat gatgattatt tccggcggtc
     9061 tcatcggtat cggctacggt tcggtcacgc cggttttcca gacgcaaatt atcagctcgg
     9121 ttgaaccgca taaaatcggt gtggcgaatt cactgttctt taacgcgatg gacgccggaa
     9181 tggcgattgg cgcctttatc atgggaatga tggttgagtc ggttggctat cgtatgattt
     9241 atgtcgctgg cgcggtgctg gtggtactcg ctggcgcact gtatgccgtg cagatgaaaa
     9301 aacgtggcgt gatgccgttg gtttccacca gcgagttgca ctgagttaca tctcgatttc
     9361 gatatcgcct tttgccctgc agcagcaggg caaaatctct cccggctgga taaacgctaa
     9421 aggttccgta atccagtcaa cctgaccggc aaccagccgg gtacgacagg agccgcaata
     9481 tccttcgcgg cactgatact ccacctcaac gttatgcgat tccagcgcgg ccagcagaga
     9541 agggtgttca tcctggcaca gcagctgtgt gccagtgata cgcagcgtga cgcgtcccat
     9601 cagagctgga aattactcag atcgtcggta tcgacttccg aatcgatttg tccgaccaga
     9661 taagaactaa cttccacttc ctgtggcgca acctgaacgt tatcggacac cagccaggta
     9721 ttgatccacg ggattgggtt ggagcgggtc tggaacggca gatccagacc cactgcctgc
     9781 atacgaatat tcgtaatata ttcaacgtat tgacacagga tatctttatt caggccgatc
     9841 atcgaaccgt cgcggaacag atagtccgcc cactcttttt cctgctgcgc cgcctgcacg
     9901 aacaggtcat agcattcctg tttacactct tcggcgattt ccgccatctc cgggtcgtcc
     9961 acgccgctac gcaacaggtt cagcatatgt tgcgtgccgg tcagatgcag cgcttcgtca
    10021 cgggcgatca gacggataat tttggcgttg ccttccatca gttcacgctc ggcaaatgcg
    10081 aaagagcagg cgaagctgac gtagaagcgg atggcttcca gcgcgttcac gctcatcagg
    10141 cacagataca gttttttctt cagctcacgc agattcacga caaccgtttt gccattaacg
    10201 gtatgggtgc cttcaccgag cagatgccag taactggtca tctcaataag ttcgtcgtag
    10261 taggcggaga taccttcggc gcgcttctga atttgctcat tggtcacgat atcgtcaaac
    10321 acgaccgccg gatcgttgac gatgttacga ataatgtggg tgtaggatcg tgagtgaatc
    10381 gtctcagaaa acgcccaggt ctctacccac gtctccagct ccgggatgga aatgagcggc
    10441 agcagggcga cgttcgggct acgtccctga atggaatcca gcagcgtctg gtatttgagg
    10501 ttgctgatga agatatgttt ttcgtgctcc ggcaacgcct gatagtcgat acgatcgcgg
    10561 gagacgtcga cctcttccgg acgccagaag aaagagagct gtttttcgat cagtttttcg
    10621 aagatgtcat atttctgctg gtcatagcgt gcaacgttga ccggctggcc aaagaacatg
    10681 ggttccttga gctgatcgtt tttcgtttgt gaaaaagtgg tgtatgccat tgaagtgaat
    10741 cctttatggg atgagcgccg gatggcggcg caagcgcctt atccggccta caaaccgtac
    10801 aatcgtaggc cgggtaagca tagcgctacc cggcactatt catcagatct tacaagcgcc
    10861 gctttcgcag ccatcgtcct gaatagaagg cgccaaatcg tcctgcgcat cttccgcgcc
    10921 gtcgcgggta ttttgatagt acagagtttt cacgccaaac ttatacgcgg tgagcaaatc
    10981 tttcagcagt tgctgcatcg gcacttttcc tgacgggaaa cgtgacggat cgtagttggt
    11041 attagcggaa atcgactggt cgataaactt ctgcatgata cccaccagtt gcagataacc
    11101 gtcgttgttc ggcatctccc acaacagttc gtaagcgtct ttcagatgct cataatccgg
    11161 cacgacctga cgcaaaatac cgtctttcga ggccttgatg ctgacgtagc cgcgcggtgg
    11221 ttcgataccg ttggtggcgt tggagatctg ggatgacgtt tccgacggca ttagcgccga
    11281 tagcgtggag ttacgcagac cgtgggtttt gatcgactca cgcagctgtt cccagtcgta
    11341 gtgcagcggt tcgttgacga tcgcatccag atcttttttg taggtgtcga tcggcaaaat
    11401 gccttttgca taggtggttt cgttgaacca tgggcaggcg ccttgctctt tcgccagttc
    11461 gttggacgct ttaagcagat agtactgaat ggcttcgaag gttttatgcg tcagattatt
    11521 ggcgctgccg tcggaataac gtttaccgtt tttcgccagc cagtaggcga agttaatcac
    11581 gccaatgccc agcgtacgac ggcccattgc gccgcgtttg gcagccggaa tcgggtaatc
    11641 ctgataatcg agcagagcat ccaaagcgcg tactgccaga atagccagtt cttccagctc
    11701 gtccagagtc ttaatggcac ccaggttgaa ggcagacagc gtacacaacg caatttcgcc
    11761 gttttcatcg ttgacatcgt tcagcggttt ggttggcagg gcaatctcca gacacaggtt
    11821 agactggcgt accggggcga caaccggatc gaacggactg tgagtattgc agtggtcaac
    11881 gttctggata tagatacgac cggtagaggc gcgttcctgc atcatcagcg agaacagttc
    11941 gaccgctttc acacgctgtt tgcggatgct gtcgtcgttt tcatacttca cgtacaggcg
    12001 ttcgaattcg tcctggtcgg cgaagaatgc atcgtatagc ccgggtacat cggacggact
    12061 gaacagcgta atgtcgccgc ccttcagcag gcgggtgtac atcagtttgt tgatctgtat
    12121 gccgtagtcc atgtgacgta cgcggttgcc ttccacgcca cggttgtttt tcagcaccag
    12181 caggctttcc acttccagat gccacatcgg gtagaacagt gtcgccgcgc cgccgcgcac
    12241 gccgccctgc gagcaggatt tcaccgccgt ctggaagtgc ttgtagaacg gaatacagcc
    12301 ggtgtggaac gcctcgccgc cacgaatcgg gctacccagc gcacgaatgc ggccagcgtt
    12361 gatgccgata ccggcgcgct gggaaacgta tttcacaatc gcgctggagg tggcgttgat
    12421 ggaatccaga ctgtcgccac actcgatcag tacgcaggag ctgaactgac gggtcggggt
    12481 acgcacgccg gacatgatgg gcgtcggcag cgagattttg aacgtagaga ccgcatcgta
    12541 aaaacgtttt acatagtcaa gacgcgtttc acgcggatag ttagagaaca ggcaggccac
    12601 taccagaatg tagaggaact gcgcgctttc atagatttcg ccggtcacgc ggttttgcac
    12661 cagatatttc ccttccagct gcttaacggc agcgtaggag aaggtcatat cgcgatcgtg
    12721 aacgataaac gaatccatct gcttgaactc ttcttccgtg tagtcttcca gcagatgatt
    12781 gtcgtatttg ccaagctcaa ccatttttac cacatggtgg taaagtgcgg gcggctcaaa
    12841 ctggccgaag gctttcttac gcaggtggaa aatcgccaga cgcgcagcca ggtattgata
    12901 atccggcgca tcgcgagaga tcaggtctgc ggcggcctta atgatagttt catggatatc
    12961 ggaggtctta atcccatcat aaaactgaat atgcgagcgt agctcgacct gagaaaccga
    13021 tacgttattc agtccttctg ccgcccaatc aagcacgcga tgaattttgt cgagattgat
    13081 gcgctcagta cggccgtcac gctttgtcac cagcagactc tgattcatgt agttttctac
    13141 ctgtttacct gtccgtgaaa gaaaaatatc ccccccgctt atccacaacg ccacgttgtg
    13201 actaactctg tggataaata ctatatatag ggggtaatcg ataagtgaaa cgctatatgg
    13261 tgagtattct agtagggatt cttttgagta caagagttga ttttggcgtt aaattgcggt
    13321 tgtaaaagag taagaatcgc taaatgcgcg tctgataagg cctggagagg atgtcaacaa
    13381 ttcataaaaa aatcaaaatt tgatcgaatg ctgatttttt catcgaagag aaaggttgcg
    13441 cccgatgatc taacgcaacc cttataggaa aattctttga tgtcaggctt ttttagcgcg
    13501 ggtatgcaac atgtagttaa cgtctactcc gggaccgagt ttgaaagtat tggttatcgg
    13561 gttgtagtgc agcccggtga tatgttgctc tttcaggacg gtttcatcta cccagcttaa
    13621 cagttcagca ggcttaatga atttcttcac gtcgtgcgtg ccttttggca ccatgcgcag
    13681 aatatactca gcgccgacga ccgccatcag ccaggatttc ccattgcggt tcaacgttga
    13741 gaagaacacc tcgccgccgg gtttaaccag ttgggcgcag gcgtggacga ccgattgcgg
    13801 atcgggaacg tgctccagca tttccataca ggtgacgacg tcgtattgct gggcgtgttt
    13861 tgccgcatgt tcctcaaccg tctcctgcac gtactctacc tcaatgccgc tttccagcgc
    13921 atgcagtttg gcgacctgca aaggctcaaa gcccatatcc agcccggtaa cggtagcgcc
    13981 ttcgcgcgcc atgctctccg ccagaatacc gccgccacag ccgacgtcga gcaccttttt
    14041 accgaacagg ccgcctgagc gctcagtaat gtagccaagg cgtagggggt tgatgcgatg
    14101 caatggcttg aattcgccct tcagatccca ccagcgcgac gcgacggctt cgaatttggc
    14161 gatttcatta tggtcaacgt tgtgagctac cgacggtttt tcagtgttca tgagtacatg
    14221 agattccgct attgatctat cggggcagta tagcaggtgc aaagtcgctg cgttatatct
    14281 actgccgtct ttattacgct ttcagcgcaa gaagttttct tgcgcgttct gtaaaaccgc
    14341 taccgatgtg gtgcgtgata aaattacaga cgccctcgac gttgttgttt tttaacatat
    14401 ctaaaatagt ggcatgtcca cggttagagc tggtgatata ttcagcggta aaatccagtc
    14461 tgtagcgaat tgccaataaa cgtgcagaga tcaacaggtg tgcttgtgaa atgtatttat
    14521 tatcggcata tttcacaaaa acataatgaa aatcatgatc cagtttgagg taagcttgcg
    14581 tatctcgctc tgcattaatt tttgctgact tcgataaaat attgcttaat tcgactatga
    14641 cattgttagc atttttctcc atcgcttcac gaattgcgcc ctgttcaagg ataaccctca
    14701 ttttgatgag atcattgata tcctcgtcgg tgacagaaaa aacaaatgtc ccactgcggg
    14761 gaatgatgtt gaccaggttt tcattatagc tcagccaaat aaaagcttca cgaattggtg
    14821 ttttacttat catcagaata tttgatagtt cattttcact gatcgcttgc ccaagatcga
    14881 aatcgccatg gataatcatc tcccttattt tctctttaat cacctgggtg atggatttgg
    14941 gtatttcaat tgatatgtga ctaaaatcac gctttaatct atttttcatt ttcttctcct
    15001 ccatggttaa acccggctcc attgtaatta atttattcaa aattaacgga tctaatatat
    15061 cagatataag aaaatt
//
LOCUS       DAJVKX010000114        14903 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.114, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000114 DAJVKX010000000
VERSION     DAJVKX010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14903
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.114"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(32..790)
                     /gene="chbG"
                     /locus_tag="OPY25_003444"
     CDS             complement(32..790)
                     /gene="chbG"
                     /locus_tag="OPY25_003444"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HCS0928963.1"
                     /translation="MERVLIVNADDFGLSKGQNYGIVEAYRNGVVTSTTALVNGEAID
                     HAAQLSRELPALGVGMHFVLTLGKPVSEMPGLTRDGLLGKWIWQMAEEDTLPLDEIAH
                     ELACQYQRFIDVFGREPTHLDSHHHVHMFPQIFPIVARFAAQRGIALRIDRQTVLNAD
                     DLPSDLRSTQGFSSEFYGEEITEACFLRILDASAHRGEASLEVMCHPAFVDNIIRQSA
                     YCYPRLTELEVLTSASLKAGIAERVYRPGSFLDI"
     gene            complement(803..2158)
                     /locus_tag="OPY25_003445"
     CDS             complement(803..2158)
                     /locus_tag="OPY25_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCS0928964.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVTELWLVDVEDG
                     KKKLGIIYDLCQRMIDKAGVPLKLYKTLDRREALKGANFVTTQLRVGQLKARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIIKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTNFKKFIGVCNIPVDMKMFIHDVLALNENDDLSIDLFGLNHMVFIKDVLVNGTSRF
                     AELLDGVASGQLKASTVKNIFDLPFSEGLIRSLNMLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFDLYKNPELNVKPKELEQRGGAYYSDAACEVINAIYNDKQT
                     EHYVNIPHHGHVENIPADWAVEMTCILGRNGATPHPRITRFDEKVLGLIHTIKGFEVA
                     ASNAALSGNFNDVLLALNLSPLVHSDRDAEVLARELILAHEKWLPNFAACIEALKGKH
                     H"
     gene            complement(2283..3125)
                     /gene="chbR"
                     /locus_tag="OPY25_003446"
     CDS             complement(2283..3125)
                     /gene="chbR"
                     /locus_tag="OPY25_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HCS0928965.1"
                     /translation="MMQLQVNATEIKTVYEQQLFNGKNFHVFIYNKTESVTGLHQHDY
                     YEFTLVLTGRYYQEINGKRVLLERGDFVFIPVGSNHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPFCFVASQVYRANSTFLTYIETVIASLNFRGNGLDEFIEVVTFYIINRLRH
                     YREEQVYDDIPQWLKATVEIMHDKTQFGEHALENMVRLSAKSQEYLTRATRRYYSKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAYEAGYSSPSLFIKTFKKMTSFTPNSYRKRLT
                     EINE"
     gene            complement(3136..3483)
                     /gene="chbA"
                     /locus_tag="OPY25_003447"
     CDS             complement(3136..3483)
                     /gene="chbA"
                     /locus_tag="OPY25_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HCS0928966.1"
                     /translation="MFDLENVVDNQTAAEELEEVVMGLIINSGQARSLAYGALRKAKE
                     GDFEAAKAMMDQSRIALNEAHLVQTKLIEGDQGEGKMKVSLVLVHAQDHLMASMLARE
                     LIAELIELHEKLK"
     gene            complement(3534..4892)
                     /gene="chbC"
                     /locus_tag="OPY25_003448"
     CDS             complement(3534..4892)
                     /gene="chbC"
                     /locus_tag="OPY25_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HCS0928967.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGAFFYSMGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSIMGIIAWALSNYGSNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGSLALTALDSGIMTPWALENISIYQQ
                     YGSVDAALEAGKTFHIWAKPMLDSYIFLGGSGATLGLIIAIFLASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFILVQPILAAITLVAYYLGIIPPITNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLAVATLIYLPFVVVANKAQNAIEQEESEEDIANAL
                     KF"
     gene            complement(4975..5295)
                     /gene="chbB"
                     /locus_tag="OPY25_003449"
     CDS             complement(4975..5295)
                     /gene="chbB"
                     /locus_tag="OPY25_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HCS0928968.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGPAADVVLLGPQIAYMLPEIQRLLPGKPVEVIDSMLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(5596..5937)
                     /gene="osmE"
                     /locus_tag="OPY25_003450"
     CDS             complement(5596..5937)
                     /gene="osmE"
                     /locus_tag="OPY25_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HCS0928969.1"
                     /translation="MNKNVAGILSAAAVMTMLAGCTAYDRTKDQFVEPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAPKQ"
     gene            6155..6982
                     /gene="nadE"
                     /locus_tag="OPY25_003451"
     CDS             6155..6982
                     /gene="nadE"
                     /locus_tag="OPY25_003451"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCS0928970.1"
                     /translation="MTLQQEIIQALGAKPHINPEEEIRRSVDFLKAYLKTYPFLKSLV
                     LGISGGQDSTLAGKLSQMAITELREETGDNALQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTHGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLHRLNKRQGKQLLAALGCPEHLYKKVPTADLEDDR
                     PSLPDEAALGVTYDNIDDYLEGKTLDSAIAKTIEGWYVKTEHKRRLPITVFDDFWKK"
     gene            7103..7984
                     /gene="cho"
                     /locus_tag="OPY25_003452"
     CDS             7103..7984
                     /gene="cho"
                     /locus_tag="OPY25_003452"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HCS0928971.1"
                     /translation="MVRRQSAPRLEFEAAAIYEYPEHLRPFLSEAPALPGVYIFHSES
                     DTLPLYIGKSVNIRSRVLSHLRTPDEAAMLRQARRISWICTAGEMGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCSLQLSEQKIEVVSARSVDFSHEPNLFGLFANRRAALQSLQNLA
                     DEQKLCYGLLGLEPVSRGRACFRFALKRCAGACCGQETPQAHFLRLQASLERLRVVCW
                     PWKGAIALKESRPQMTQFHIINNWLWLGAVPSLDEAATLVRTPAGFDQDGYKILCKPL
                     MSGQYEIIELHTDCRQS"
     gene            complement(8059..8544)
                     /gene="spy"
                     /locus_tag="OPY25_003453"
     CDS             complement(8059..8544)
                     /gene="spy"
                     /locus_tag="OPY25_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HCS0928972.1"
                     /translation="MRKLTALFVASTLAMGAANLAHAAETTTAAPADAKPMMQHKGKF
                     GPHHDMMFKNLNLTDAQKQQIRDIIKAQREQMERPLLEERRAMHDIIASDTFDKAKAE
                     AQITKMEAQRKANMLAHMETQNKIYNVLTPEQKKQYNANFEKRLTERPAQEGKMPAAA
                     E"
     gene            complement(8880..9848)
                     /gene="astE"
                     /locus_tag="OPY25_003454"
     CDS             complement(8880..9848)
                     /gene="astE"
                     /locus_tag="OPY25_003454"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HCS0928973.1"
                     /translation="MDNFLALTLSGTTPRVTQGKGAGFRWRWLGHGLLELTPDAPVDR
                     ALILSAGIHGNETAPVEMLDKLLSALYSGSLTLTWRVLVVLGNPQALAAGIRYCHSDM
                     NRMFGGRWQSFAESDETRRARELELSLETFFSSGQARVRWHLDLHTAIRGSHHLRFGV
                     LPQRDRPWEADFLAWLGAAGLEALVFHQAPGGTFTHFSSEHFGALSCTLELGKALPFG
                     QNDLTQFSVTSQALSALLSGVETSTSFSPPLRYRVVSQITRHSDKFALYMDAQTLNFT
                     AFAKGTLLAEEGDKRVTVTHDVEYVLFPNSSVACGLRAGLMLERLP"
     gene            complement(9841..11184)
                     /gene="astB"
                     /locus_tag="OPY25_003455"
     CDS             complement(9841..11184)
                     /gene="astB"
                     /locus_tag="OPY25_003455"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HCS0928974.1"
                     /translation="MTAHEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAVKQ
                     GLLKMKALADAGFPQAVIPPHERPFIPALRQLGFTGSDEQILDKVARQAPRWLSSVSS
                     ASPMWVANAATVCPSADALDGKVHLTVANLNNKFHRALEAPVTEALLRAIFRDESQFS
                     VHSALPQVALLGDEGAANHNRLGGEYGSAGVQLFVYGREEENEIRPARYPARQSREAS
                     EAVARLNQVNPQQVIFAQQNPEVIDQGVFHNDVIAVSNRQVLFCHEAAFARQKVLINQ
                     LRTRVDGFMAIEVPAGEVSVSDAVATYLFNSQLLSRDDGSMLLVLPRECQDHAGVWRY
                     LNKLVAEDNPISAMQVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDALFT
                     ALNAWADRYYRDRLTAADLADPLLLREGREALDVLTRLLDLGSVYPFQQTGAADG"
     gene            complement(11181..12659)
                     /gene="astD"
                     /locus_tag="OPY25_003456"
                     /pseudo
     CDS             complement(11181..12659)
                     /gene="astD"
                     /locus_tag="OPY25_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460271.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
     gene            complement(12656..13690)
                     /gene="astA"
                     /locus_tag="OPY25_003457"
     CDS             complement(12656..13690)
                     /gene="astA"
                     /locus_tag="OPY25_003457"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HCS0928975.1"
                     /translation="MRVIRPVEHADIAALMQLAGKTGGGLTSLLANEATLAARIERAL
                     KTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     EEAQAVIGEVHPQTAPARVVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPALGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRL
                     VRLCAEEKTV"
     gene            complement(13681..14901)
                     /locus_tag="OPY25_003458"
     CDS             complement(13681..14901)
                     /locus_tag="OPY25_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HCS0928976.1"
                     /translation="MSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAG
                     GIAVNALGHAHPALREALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNS
                     GAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLP
                     PDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATNAFLQGLRELCDRHQALL
                     IFDEVQTGVGRTGELYAYMHYGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTH
                     GTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLG
                     LLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFA
                     LACERLQAGGASCG"
BASE COUNT         3637 a         4222 c         3593 g         3451 t
ORIGIN      
        1 gcggcgcatt cttgcgccgc aaactcagga gctaaatatc aagaaaactg ccaggacgat
       61 atacacgttc cgcaatccct gccttgagtg acgcagacgt caacacctcc agttcagtta
      121 agcgggggta acaataggcg ctctggcgaa taatgttgtc cacaaacgcc ggatgacaca
      181 tcacctccag agaggcttct cctcgatgcg ccgaggcatc cagaatgcgt aaaaagcacg
      241 cttcggtgat ctcctcgccg taaaattcac tactaaatcc ttgagtgctg cgcaaatccg
      301 acggcagatc gtctgcattc aacaccgtct ggcggtcaat acgtaacgca atcccgcgct
      361 gcgccgcaaa gcgggcgacg atggggaaaa tttgcgggaa catatgcaca tgatgatgac
      421 tgtcgagatg cgttggctcg cggccaaata cgtcgatgaa acgctgatac tgacacgcca
      481 gttcatgcgc aatttcatcc agcggaagcg tatcctcctc cgccatttgc cagatccatt
      541 tccccaacag gccgtctcgc gtcaggcccg gcatctctga caccggtttg cctaacgtca
      601 aaacaaaatg cattcccacc ccaagcgcag gcagctcgcg gctaagctgc gccgcatggt
      661 caatagcctc gccattgacc agcgccgtcg tggaggtcac aacgccgttg cgatatgctt
      721 caacaatgcc gtaattttgc cctttactca ggccaaaatc atcggcattc acaatcaaca
      781 cgcgttccat agcctacctc tgtcagtggt gcttaccttt aagcgcttcg atgcaagcgg
      841 caaaattagg cagccatttt tcatgcgcca gaatgagctc acgcgccagg acttctgcgt
      901 ctcggtcgga atgcaccagc ggactcaggt taagcgccag cagcacatca ttaaagtttc
      961 cgctcagcgc cgcattgctg gccgcgacct caaatccttt aatagtgtgg ataagcccca
     1021 gcactttttc gtcaaaacgg gtgatacgcg ggtgcggcgt cgcgccattg cgtcccagaa
     1081 tgcaggtcat ttccaccgcc cagtccgccg ggatattctc gacatgccca tgatgtggaa
     1141 tattaacata atgctcagtc tgcttgtcat tataaatagc gttaatgact tcacaagcgg
     1201 catcggaata ataagcgccg ccgcgttgct caagctcttt cggcttcacg tttagctcag
     1261 gatttttgta caagtcgaag agttgtttct ccactttttg tacgacctga gcgcgcgcgc
     1321 cgcctttgta atattcgccc atttcaatcg ccagcatctc tttttgcttg aagtaataca
     1381 acaaataaga gcacggcagc atgttcagcg agcgaatcaa tccttcacta aacggcagat
     1441 caaagatatt ttttacggtt gacgctttca actgaccgga cgccacgcca tccagtaatt
     1501 ctgcgaaccg tgaggtgcca ttcaccagca catctttaat aaagaccata tggtttagac
     1561 caaacaggtc aatggaaaga tcgtcattct cattcagcgc cagcacgtca tgaataaaca
     1621 ttttcatgtc gacaggaata ttacatacgc cgatgaattt tttaaagttg gtatgacgat
     1681 aaaccgcttc cgtcaccatc cccgccgggt tagtaaagtt aatgacccac gcattcggac
     1741 ataattcttc aacatcctta atgatgtcaa aaataaccgg aatggtacgc aaccctttaa
     1801 ataaaccgcc agcgccgttg gtttcttgcc ccagatagcc gtggctaagc gggatacgct
     1861 cgtccagctc acgggctttg agttgaccaa cgcgtagctg ggtagtgaca aaattagcgc
     1921 ctttcagcgc ttcccggcga tccagcgttt tatacaattt tagcggaacg cctgctttat
     1981 caatcattcg ctggcagaga tcataaataa tgcccagctt ctttttcccg tcttcaacgt
     2041 caaccagcca taattcggtg acaggtaatt catggtagcg cttaataaag ccttcaagta
     2101 attcaggggt gtagctgctc ccgccaccaa tagtgacgac ttttaatttc tggctcataa
     2161 tatctccctt cagtgtatga cactgatatg tattacgcta tgcccgctcg taagaaatag
     2221 cgtgacgttc cccgcgctat tggggcaagc gtgaaatgta actaatcgag caatgtaaac
     2281 cgttactcat taatttccgt caatcgcttc cgataactat tcggcgtgaa tgaggtcatc
     2341 ttcttaaacg ttttaataaa cagacttgga ctactgtacc cggcttcata agcaatatcc
     2401 gtaaccgaat agttggtcat ttccaactgt ttcttggcaa aattaatgcg aatctcatta
     2461 atgatttgca tcggcgtttt gctgtaataa cgtcgggtgg cgcgcgtcag atactcctgg
     2521 gattttgccg acaggcgcac catattttcc agcgcatgtt cgccaaactg cgttttatca
     2581 tgcattatct ccacggttgc tttcagccat tgtggaatat catcataaac ctgctcttcg
     2641 cggtaatgac gtaagcggtt tataatataa aatgtcacca cttcgataaa ttcgtcgagc
     2701 ccattgccgc gaaaattcaa cgacgcaatc accgtttcaa tataggtaag gaaggtgcta
     2761 ttcgccctgt atacctgcga tgccacaaaa caaaacggca gtaacggaag ataatgctgt
     2821 tcaaaaaaac gtttactaat tcctacgttc agaatacgcg ttgcgccaaa ctcatagaaa
     2881 ctttggtgat tcgaccccac cgggataaaa acaaaatctc cacgttccag cagcacacgc
     2941 ttcccgttaa tctcctggta ataacgtccg gttaatacca gggtaaattc ataatagtcg
     3001 tgctgatgca gcccggtgac gctttccgtc ttgttataga taaacacatg gaaatttttg
     3061 ccattgaaga gctgctgctc ataaaccgtt ttgatttccg ttgcgttaac ctgtagctgc
     3121 atcatccgcc ccctgttatt tcagtttctc atggagctca atcaactcag cgatcagttc
     3181 acgagccagc attgaggcca tcaaatgatc ctgagcgtga accaggacca gactgacttt
     3241 cattttgcct tcgccctgat cgccttcgat gagttttgtc tgcacaagat gcgcttcatt
     3301 gagcgctatg cgcgactggt ccatcatcgc tttcgccgcc tcaaagtcgc cttctttcgc
     3361 ttttctgagc gcgccatatg ccaggctgcg cgcctgacca gaattgatga taagccccat
     3421 aacgacttct tcgagttcct cagccgctgt ctggttatct acaacatttt caagatcaaa
     3481 catagtcttt cctctgattc agcccggcat ggcatcccat gccgacgcgg agtttagaat
     3541 ttcagtgcgt tagcgatatc ttcttcgctt tcttcctgct cgatggcgtt ctgcgctttg
     3601 ttagccacca ccacgaaggg gagataaatc agggtagcga ccgccaggtt aaatagcgca
     3661 accagcaacg cggcgacact gccgttggtg ttaaagaacg cccccagccc ggttggcatg
     3721 gtccacggcg caatattggt aatcggcgga ataataccca aatagtaagc caccagcgta
     3781 atcgccgcca gaatcggctg aaccagaatg aaggggataa acatcaccgg gttcataata
     3841 atcggcaggc caaacaggat gggttcgtta atctggaaga tacctgacgg cagcgccagt
     3901 tttgccacct ggcgatagtc cgcgcgacgg gatgccagga agatagcgat gatcagaccc
     3961 agcgttgcgc cgctaccacc gaggaagata taagaatcca gcatcggttt cgcccagata
     4021 tggaacgttt taccggcttc cagcgccgca tcgacggagc catactgctg gtaaatagag
     4081 atgttttcca gcgcccaggg cgtcatgatg ccgctgtcca gcgcggtcag cgccagcgaa
     4141 ccatgaatac caaagaacca cagcagcggt acaaaaatga catatgccca ccctaccacg
     4201 ctacccagcg atgccagcgg cgtagagata gtgtccataa taatctgatg gaagttagaa
     4261 ccgtaattag acagcgccca ggcaataatc cccataatag agagaataat aaagccggga
     4321 attaatgctg agaatgaacg agacaccgaa gccggtacgc tgtccggtag tttaatcacc
     4381 cagttgcgcc ggacaataaa tgtaaacatc tccgcgacca ccaggccaat aataataccg
     4441 gagataatat tcgcgccgcc cagccagtta gcgcctacgg cataggcctc gccgacacta
     4501 tacggcgtta cggtcataaa tgccgccacg gagagcagtc cggcggccag cgcatcaacc
     4561 ttgcgctctt ccgccagcgc catgccgata aaaaatggcg ccatgagcga cataatgccc
     4621 aatgtgccgt tatagacgtt cccgccgatg cctttcaatc cattaagtgt ttcaatggtt
     4681 gaggcatcaa gccgaatgcc catggaataa aaaaacgccc cctccccaaa gctcaggaaa
     4741 acgttattaa ttaatacaaa catcgccccc gcaagggtta atggcattaa acgaataaag
     4801 ccgttcttga ttgcattaac gtgtggctgc tttcctattt ttacagcaaa aggaaggagt
     4861 accttttcaa gtgaagcaat aacgttactc atagaaaaat acccttaaat accgcaataa
     4921 aatattgcgg ttagtgtatg aaataactct ttgacgggaa aaattaaaaa ataattaatt
     4981 cgcggcggct tttttaattg ccgctaccgc agctttaagc acgcctaagc catctacctt
     5041 gccgtacaac attgaatcaa tgacttctac cggtttaccg ggtaataaac gctgaatttc
     5101 ggggagcata taagcaattt gcgggcctaa taacacgacg tccgctgccg ggcctttttc
     5161 accggccagg gtttcaggga atgcttcaat aatcaccggc acttcatatt tttcagcctg
     5221 agcgcgcatt tttgatacca gtaacgatgt tgacatgccc gcagaacaaa acagataaat
     5281 gtgtttcttt tccataaaaa ccttcctcat gtgcgattat ctgtcaacca gatacgccgc
     5341 aagcctcaac ctgcatccat actctgggcg acttgcgtaa ccggatttac ttttttaggt
     5401 ggctgaaatg agtatacggg atcggaccgc cggatggtat ttccttgacc cactaaattg
     5461 tctctcattg acctggcgtt atgacccccc tcacatttcg ggcaaataat tcgcgataat
     5521 aaataaggtt atggcaggca caaaaaaacc ggctcgcagg ccggtttcct tgaatgttca
     5581 ggcaatgtac agttgttact gcttcggcgc ctgtgggtca gtgtcgtact ccgcacaggt
     5641 ctggtagccg gagttaatca cgtgcccggt atcatccagc gcaacaaagt aggtttccgc
     5701 tttaccatca cgttgaccca ggatgtaggt ctgacaggta ccacgcgcat gaatcatgct
     5761 cacttcagat gacggtttgc ccgcaatctg cgcaacttgc gccctgctca ttcctttttt
     5821 aacatcttta acgacaggct caacaaattg gtcttttgta cgatcatacg ccgtacagcc
     5881 tgccagcata gtcattaccg ccgctgcgct taaaattcct gctacgttct tgttcatttt
     5941 ccgtcctctt gtttatcagc gtgttatgta agcctggaat acatcagaac atttttcaag
     6001 ccgcgcctcg cgacaaaaag tctttcggaa aattctctaa cgcagcgata tgttgtttta
     6061 aacaccgctt agcccgccaa accttgtcgt ttcagcggcg aagggttagc tttaacaggg
     6121 taaagattca ttttttaatg tcgaaggggg ttaaatgact ctgcagcaag agataatcca
     6181 ggcgcttggc gcgaaaccgc atatcaaccc tgaagaagaa attcgccgca gcgtggattt
     6241 tcttaaagcg tacctgaaaa cctatccctt tttgaaatcg ctggtgttag gcatcagcgg
     6301 cgggcaggat tcgacgctgg ccgggaaact cagccagatg gctatcaccg aattgcggga
     6361 agagaccggt gataatgcgc tgcagtttat cgccgttcgt ctgccttatg gcgtgcaggc
     6421 cgatgaacag gattgccagg acgccattgc ttttattcag ccggacagag tactcaccgt
     6481 caatattaaa ggcgccgtcc tcgccagcga acaggcgctg cgcgaagcgg gaattgagct
     6541 gagcgatttt gttcgcggca atgaaaaagc gcgtgagcga atgaaagcgc aatatagcat
     6601 cgccggtatg actcacggcg tcgtggtggg caccgaccat gcggcggaag cgataaccgg
     6661 gttcttcacc aaatatggcg atggcggtac cgatattaac ccgcttcatc gccttaacaa
     6721 acgccagggc aaacagcttc tcgcagcgct gggctgtcct gagcatctgt ataaaaaagt
     6781 ccccaccgcc gatttggaag acgaccgccc ttcactgcct gatgaagccg cgctgggcgt
     6841 aacgtatgac aatattgacg attacctgga aggcaaaacg ctggactccg ccatcgctaa
     6901 aactatcgaa ggctggtacg taaaaactga acataagcgc cgtttaccga ttacggtatt
     6961 cgacgacttt tggaaaaagt aagcgtactt ctactgttgt gccggatatc gctcgtctat
     7021 ccggcctcct ctcttcccag cctctttttt aatcacccat ccgctgttat actggatgaa
     7081 taaccagtta acggagatca ctgtggtacg gcgtcaatca gccccccgcc ttgagtttga
     7141 agcagcggcc atttacgaat atccagaaca tttacgtcct ttcctcagcg aagcgccagc
     7201 cttaccgggc gtctatatat ttcatagcga aagcgatacg ctgccgcttt atatcggtaa
     7261 aagcgtaaat attcgcagcc gggtgctctc acatctgcga acgcctgacg aggccgctat
     7321 gctgcgacag gcgcggcgga taagctggat ctgcaccgct ggggaaatgg gcgcgttgct
     7381 gctggaggcg cgactgatca aagaacaaca gccgctgttt aacaagcggt tacgtcgtaa
     7441 tcgccagctt tgctctctac agttgagcga acaaaagatt gaggtcgttt ccgcccgcag
     7501 cgtcgatttt tcccatgagc cgaacctgtt tggactcttc gccaaccgtc gggcagcgct
     7561 gcaaagctta cagaacctcg ccgatgaaca aaaattgtgt tatggcctgc tggggcttga
     7621 accggtaagc cgtgggcgcg cctgttttcg tttcgcgctg aagcgctgcg ctggcgcgtg
     7681 ttgtgggcaa gaaaccccgc aggcgcattt tcttcgtctg caggcctcac tggaacggtt
     7741 acgtgtggtt tgctggccct ggaaaggcgc tatcgcgtta aaagagagcc gcccacaaat
     7801 gacccagttc cacattatca acaactggtt atggctgggg gcggtaccct cgctggatga
     7861 ggccgccacc ctggtgcgca cccctgcggg ctttgatcag gatggctata aaattctctg
     7921 taagccacta atgtcaggtc aatatgagat cattgaactg cacaccgact gtcgccagtc
     7981 ataaagaaaa ccgccgatcc tgtccacctc aacgattgtg ttgtcgacaa gaccggcggt
     8041 cttaaattat gcggaaagtt attctgccgc agcaggcatt ttaccttctt gcgccgggcg
     8101 ttctgtcaga cgcttctcaa aattagcgtt atattgcttt ttctgctccg gcgtcagaac
     8161 gttataaatt ttattctggg tttccatatg cgccagcata ttggccttgc gctgtgcttc
     8221 cattttcgta atttgcgctt cggctttggc tttatcgaag gtatcgctgg caataatatc
     8281 atgcatggcg cgacgctctt ccagcagcgg acgttccatt tgctcgcgct gcgcttttat
     8341 aatgtcgcga atttgttgct tctgcgcgtc tgtcaggttc aggtttttaa acatcatatc
     8401 gtgatgtggg ccaaatttac ctttatgctg catcattggc ttcgcatccg ctggcgcggc
     8461 ggtggtagtc tcagcggcat gagccagatt cgcagcaccc atcgccaggg tagaggcaac
     8521 aaatagagca gtcagtttac gcatatttcc atccttcctt tcagttattt ttacggcata
     8581 tttaaaacag cgccgtgttg tcgtgattaa ctttaaccgt cttagcgtca attagtcaga
     8641 acaacggtaa aacaatgaaa gtataaaaaa cactttttcg ccaattgtga agaaaaaaag
     8701 aataaattgc gcagagttga aagagaaata tacaacagca tgatatagca gaaattatgc
     8761 agaactataa cgcagcaacg cttattaata aagcaattct ctaggaataa tccgtaatag
     8821 catgaaactg tgtcccaaat catccctgta atcctaacgt gagcttacag ggacatttat
     8881 cagggcagtc tttccagcat taatccagcc cgcaatccgc aggcgacaga ggaattagga
     8941 aagagaacat attcaacgtc atgcgtcacc gtcacgcgct tatccccctc ctcggccagc
     9001 aacgttccct tcgcaaaggc agtaaaattc agcgtttgcg catccatata aagcgcgaac
     9061 ttgtcgctgt gacgcgtgat ttgcgacacc acccgatagc gtagcggcgg cgaaaacgag
     9121 gttgacgttt cgacaccgct cagcaacgcc gacaacgcct gcgaggttac gctgaactgc
     9181 gtcagatcgt tttgcccaaa cggcaacgcc tttcccaact ccagcgtaca ggaaagcgcg
     9241 ccgaaatgtt cagagctaaa gtgcgtaaac gtaccgccgg gcgcctgatg aaataccaac
     9301 gcctccagtc ctgccgcgcc cagccacgcc agaaaatccg cctcccacgg gcggtcgcgc
     9361 tgcggcaata cgccaaaacg caaatgatgc gagccacgaa tggcggtatg cagatccaga
     9421 tgccagcgta cccgcgcctg gccagatgaa aagaaggtct ccagacttag ctccagctca
     9481 cgcgcccgcc gcgtttcatc gctttcggca aaggactgcc aacgcccgcc aaacatacgg
     9541 ttcatatcac tgtgacaata gcgtattccc gccgccagcg cctgcggatt gccgagtacc
     9601 accagcactc gccacgttaa cgtcaagctg cctgaataca gcgccgacag cagcttatcc
     9661 agcatctcga ccggcgcggt ttcattaccg tgtatccccg cagaaagaat taacgcgcgg
     9721 tcgaccggcg catcgggcgt gagttcaagc agaccatggc ctaaccagcg ccagcgaaaa
     9781 cccgcgccct tcccctgcgt cacccgtggt gtcgtgccgc ttagcgtcaa cgccagaaag
     9841 ttatccatca gccgcccccg tttgctggaa aggataaacc gaccccaaat ccagcagacg
     9901 cgttaacaca tccagcgcct cccggccttc tcgcaataat aacggatcgg ccagatcggc
     9961 agcggtcagg cgatcgcgat aataacgatc cgcccacgcg ttaagggccg taaacagagc
    10021 gtcattcatc attaccgctg gattcaccgc ccgtcgttct tcttctgtta acaccacgcg
    10081 taatcgcaga caggccgggc cgccgccgtt ggccatactt tctcgcaaat caaacacctg
    10141 catcgcgctg atggggttat cctccgccac cagcttattc agatagcgcc agacgccggc
    10201 atggtcctga cattcccgcg gcaacactaa cagcattgag ccgtcgtcac ggcttaacaa
    10261 ctgactatta aacaggtagg tggccacagc atctgataca gaaacctctc cggcgggcac
    10321 ctctatcgcc ataaaaccgt caacgcgcgt acgcaactga ttaatgagca ctttctgccg
    10381 ggcaaacgcc gcttcgtgac aaaacaatac ctgtcgattc gaaacggcga tgacatcatt
    10441 atggaatacg ccttgatcga tgacctccgg gttttgctga gcgaagataa cctgttgcgg
    10501 attcacctga ttaagacgcg ccacggcctc gctggcttcg cggctctggc gcgccggata
    10561 acgagcgggt cgtatttcat tctcctcttc gcgcccatag acaaaaagct gcacgcctgc
    10621 cgaaccatac tcgccgccaa gacggttatg attcgccgcg ccttcatctc ccaataatgc
    10681 gacctgcggt aacgcgctat gcactgaaaa ctgactttca tcgcgaaata tggcgcgtag
    10741 cagcgcttcg gtaacaggcg cctcaagagc gcgatgaaat ttattgttta aattcgccac
    10801 cgtcaggtga actttcccgt ccagcgcgtc tgccgatggg caaaccgtcg ccgcattcgc
    10861 aacccacatt ggcgacgcgg aactcacgct ggaaagccag cgtggcgcct gacgcgcaac
    10921 cttatccaga atctgctcat cgctacccgt gaagccgagc tgacgtaacg ccggaataaa
    10981 gggccgctca tgcggcggga tcaccgcctg gggaaagccg gcatccgcca gagctttcat
    11041 ctttagcagc ccctgcttta ccgccagacg aggattcgac acctgaaaac ggtggcgggt
    11101 cgatgcctca ttgccgaagg atagcccggc ataatggtgc gtaagcccca ccagcccgtc
    11161 aaaattaact tcatgcgccg tcataccgcc tccctgcgag aaaagtcgag gccagggctt
    11221 aatgtcgcag gcaacgtcag ttcgggagat tccagactgg ccatcggcca ggcgcaataa
    11281 tcggcggcat accaggcgct gggccgatgg ttgccagacg cgccgacacc accaaacggc
    11341 gcagtactcg ctgccccggt gagcggttta tttcagttaa cgatccctgc ccgcgcctcc
    11401 agcaagagtt gttcgaactg cgcgcgatcc gtcgacacca gcccacacga cagaccaaaa
    11461 cgggtattat tcgccagacg aatcgcctca tcgaaatgcg cataacgcca gacgttcagc
    11521 agcggaccaa acacctcttc atccggcaca tccgcgacgc ccgtcagctc aatgatgcca
    11581 ggcgtcagca gagaggttcc ctctttgacc ttccgcggcg ccagtagcgt gcgaccgcct
    11641 aatgcctctc gttgacgcca ggcctccatc acatgctgtg ccgcctgcgc tgaaatcagt
    11701 ccgccgataa acggctgcgg gtcgtcgtcc catctgccgg gctgcagacg tccggcgacg
    11761 tcaactagcc gcgccagaaa tgcatctccc tgcgcgccct gttttaccag aaggcgtcgc
    11821 gcgcaagtac agcgctgtcc ggcggtaata aacgccgatt gcagcgtcag atgtaccgcc
    11881 gcatccatat ttgtcgcatc ctcaataatg agcgggttgt ttccgcccat ttcaagagcc
    11941 aggatttttt ccggctggcc ggatagctga cgatgaagct gatatccggt actggcgctg
    12001 ccggtaaaca gcagtccgtc gagatcgtcg agcgaactca gcgcttgtcc ggtctcccgg
    12061 ccgccctgca ccagattaag aacgcctgcc ggtaaccccg cccgttccca gagttttatt
    12121 accgtttccc cggtccatgg cgttagctcg ctaggtttga agatcagcgt attgcctgcc
    12181 agcaacgcgg gcacaatatg gccattcggt aaatggccgg gaaagttata agggccgaat
    12241 accgccagca caccgtgagg acgatggcgc agcgtcgcgg caccatcgac aagttcgctt
    12301 ttttgttcgc cggttctggc atggtaagcc ttaatcgaga tggcaatctt attgatcatc
    12361 gccgtcactt ccgtcgccgc ctcccagcgc ggtttaccgg tttcacgcgc gatgacctcc
    12421 gtgagatcgg ctttatgcgc ctccagcagg acggaaaatt tctctacgat agcctgccgt
    12481 gccgcaaaag gctgtctggc ccagcgagga aacgccgcgc gcgccgcctg acaggcctcg
    12541 gcgacctgtg ccgcatcagc gtcattcccc tgccaaagta tctcctcgct caccggattc
    12601 gttttgcggc ggcgttcgcc ctgaccggtt atccagtcgc cgtttatcca tagcgtcata
    12661 cggttttctc ctcagcgcaa aggcgtacca gccgaacgtg gtcgcccgcg cgacatttca
    12721 gcgcatccaa ctgcgcggcg gtaagtacaa gtcgtgaagt ctgcggatcg gcacgcacca
    12781 gcgcggcccg aaagtggtga tagttttcat tggcgaccag acatgcagga tagtcgccaa
    12841 gcgcgggttg cccttccgcg acttccacca gtcggctttt acgaatagcc cgcacgcggt
    12901 caatatcaca ctccagcgtc ggcccaccgt cgaagatgtc gatatagtgg cgatagcgaa
    12961 agccttcctt ttccagcacc acgcgggctg gcgccgtttg cgggtggact tcgccaatca
    13021 cggcctgtgc ctcttcagat aagaagtggg tataaatagg atgtttgggc atcagctcgg
    13081 cgataaacgc tttttgcccg gtaccgcata aaaaatccgc ccggctgaaa tccatagaaa
    13141 aaaagcgttt gccgagactt tgccagaagg gagaataacc atgctcgtca atgacaccgc
    13201 gcatttccgc caccactttc tcattgaatt tatcgcgaaa cgcggccata aacataaagc
    13261 gcgattttga caacaagtag ccgttaccct ctttacgcca ttcgggatcg agaaacagcg
    13321 tgcaaagctc actgctgccg gtatgatcat tactcaggaa taatgttggc aacgcgttat
    13381 atacattcag ctctttggaa gcatgaacca gcgtaccgac acgatagtta taccaagggt
    13441 cgttaaggcc gaccgcgacc tcaatggcgc agatcccgcc gacctcaccc gtttcactgt
    13501 cctcgagaac aaatacatat ccttgttcgc cttttggcag ctcgccggac caggttttta
    13561 gcgcgcgttc aatgcgggcc gccagcgtcg cttcatttgc cagtagcgag gttaagccgc
    13621 cgcccgtttt gcctgcaagc tgcatcagcg cggcgatatc cgcatgttcg acaggacgaa
    13681 tcacccgcat gatgcgcctc ccgcctgaag gcgttcgcac gccagggcaa aacgatcaag
    13741 cccggtagct atctcctcgt cgctcacatt taacgctggc gcaaaacgca ccacgtcgcc
    13801 accggcgatg agcaccatca cgcctgcttt tgccgcttcc tgggcgatga gtttggcttt
    13861 tccggcaaac tccgtctgta gcacacagcc aagcagtagc cccagcccgc gaatttcact
    13921 gaacatgcca aaacgtacat taatggtatt tagacgttca ataaacgcat cgtggcgctg
    13981 tctgacgccg ttttgcatct ccggcgtatt gatgatatcc agtacttttc cggcaactgc
    14041 cgtcgccagc ggattaccgc cgtaggtggt gccatgcgta cctggcgtca tgacgctggc
    14101 atagtcttgc gtagtcagca tcgcgccgat cgggaagccg ccgcccaacg ctttagcggt
    14161 cgtcaggata tcgggcgtaa cgccataatg catatatgca tacagttcgc cggtacgtcc
    14221 gacgcccgtc tgcacctcat caaaaatcag taacgcctga tgccggtcgc acaattcacg
    14281 cagcccctgc aaaaaagcgt tcgtggcggg gatcacgccg ccctcgccct gcacaggctc
    14341 tacgattacg gcgcaggtat tgtcatcaat gagcgcgctg gcggagttca gatcgttata
    14401 ggctgcatga cgaatatccg gcggcagcgg cgcaaagtcc tgtgaatagg tgggttgacc
    14461 gccagcgctg acggtaaaga gcgtgcggcc atggaacgcg tttttaaagg ccacaatgcc
    14521 gcttttatgg ttgccaacac gatcgtgggc atatttgcgc gccagtttta atgcagcttc
    14581 atttgcttca gcgcctgaat tacaaaagaa aacgcgttcg gcgaaggtcg cgtcgatcag
    14641 ttttttcgcc agtcgcagcg ccggttcatt ggtgtaaccg ttcccggtat gccagaagcg
    14701 attcgcctgt tcatttaacg cctcgcgcag cgccggatgc gcatgtccca atgcgttgac
    14761 cgcaatcccg ccagcaaaat caatgtactc tttcccctgc tgatcccaca ggcgtgagcc
    14821 ttctccgcgt acaggaataa aaggcgcggg aacatatacc ggcaccatcc attcatcaaa
    14881 gttttcgcgc gtaactgaca gag
//
LOCUS       DAJVKX010000115        14730 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.115, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000115 DAJVKX010000000
VERSION     DAJVKX010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14730
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.115"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..1579
                     /gene="ftsK"
                     /locus_tag="OPY25_003459"
     CDS             <1..1579
                     /gene="ftsK"
                     /locus_tag="OPY25_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCS0928977.1"
                     /translation="QYQQPQQPTAPQDSLIHPLLMRNGDSRPLQRPTTPLPSLDLLTP
                     PPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARI
                     SNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRENPSPL
                     TVVLGKDIAGDPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMI
                     DPKMLELSVYEGIPHLLTEVVTDMKDAANALRWSVNEMERRYKLMSALGVRNLAGYNE
                     KIAEAARMGRPIPDPYWKPGDSMDVQHPVLEKLPYIVVLVDEFADLMMTVGKKVEELI
                     ARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQGGAE
                     SLLGMGDMLYSGPNSTMPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEG
                     GGGGFDGGEELDALFDQAVNFVTQKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVS
                     AQGHNGNREVLAPPPFE"
     gene            1724..2335
                     /gene="lolA"
                     /locus_tag="OPY25_003460"
     CDS             1724..2335
                     /gene="lolA"
                     /locus_tag="OPY25_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HCS0928978.1"
                     /translation="MKKMAIACALLSSVVASSVWADAASSLKSRLDKVSSFHATFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQASDWQQYNIKQDGDNFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSAYQLKSQQNGAVEPSKFTFTPPQGVTIDDQRK"
     gene            2345..3688
                     /gene="rarA"
                     /locus_tag="OPY25_003461"
                     /gene_synonym="mgsA"
     CDS             2345..3688
                     /gene="rarA"
                     /locus_tag="OPY25_003461"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HCS0928979.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYASADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLTTDDIEQVLDQAMQDKTRGYGDQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEADDSGKRVLLPALLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEPNAYAAGEVYFPPEIAQTRYYHPTNRGLEGKIGEKLAWLAEQDQNSPTKRYR"
     gene            3947..5239
                     /gene="serS"
                     /locus_tag="OPY25_003462"
     CDS             3947..5239
                     /gene="serS"
                     /locus_tag="OPY25_003462"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCS0928980.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDTLLAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLF
                     HTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            5476..7920
                     /gene="dmsA"
                     /locus_tag="OPY25_003463"
     CDS             5476..7920
                     /gene="dmsA"
                     /locus_tag="OPY25_003463"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HCS0928981.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSAFTLPFTRIAN
                     AAEAISPTKTDEKVVWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGNDDYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWDEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTLTRSWPPGKTLVARLMNCCGGYLNHYGDYSSAQIAAGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGGTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVLITENMVDQPFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGLGKDGIAKTPEWAAQITGIPADRIIKLAREIGSAKPAYICQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYALPFERMPTLENPVETSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDSKCEM
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFTDQAIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYEQSRKSIPNLPTFEEFRKQGIFKQRDP
                     EGHHVAYKDFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTLGF
                     ENYNDPLTDKFPLQLTGFHYKARVHSTYGNVDVLKAACRQEMWINPMDAQKRGINNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDQGGCINVLTSQRPSPL
                     AKGNPSHTNLVQVEKA"
     gene            7931..8548
                     /gene="dmsB"
                     /locus_tag="OPY25_003464"
     CDS             7931..8548
                     /gene="dmsB"
                     /locus_tag="OPY25_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HCS0928982.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKRDDGFVVVNEEVCIGC
                     RYCHMACPYGAPQYNAAKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGELAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            8550..9413
                     /locus_tag="OPY25_003465"
     CDS             8550..9413
                     /locus_tag="OPY25_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HCS0928983.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALMKGDLRAETQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSVFFAVGGIGW
                     LLAVLKKLPPALRTLWLIITMVLGVVFVWMMVRVYNSIDTVPTWYSVWTPLGFFLTLF
                     MGGPLLGYLLLRIAGVNGWAMRLLPAVSVLALVVIAIMVAMQGAELATIHSSIQQASA
                     LVPDYGSLMAWRMVLLAAALCCWIVPQLKGYQPAVPLLSVAFILMLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            9763..10911
                     /locus_tag="OPY25_003466"
     CDS             9763..10911
                     /locus_tag="OPY25_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0928984.1"
                     /translation="MSIYTRPVMLLLCGLLLLTLAIAVLNTLVPLWLAQANLPTWQVG
                     MVSSSYFTGNLVGTLFTGYLIKRIGFNRSYYLASLIFAAGCVGLGVMVGFWSWMSWRF
                     IAGIGCAMIWVVVESALMCSGTSHNRGRLLAAYMMVYYMGTFLGQLLVSKVSGELLHV
                     LPWVTGMILAGILPLLFTRIVNQQTQARHSSSISAMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLKHQGMANASIGFWMAVLVSAGILGQWPMGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLTQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFAAMLMQNYSDNLLFIMIASVSFIYLLMLLRNVGQTPNPVAHI"
     gene            11129..12550
                     /locus_tag="OPY25_003467"
     CDS             11129..12550
                     /locus_tag="OPY25_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCS0928985.1"
                     /translation="MPNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWV
                     FIFALYFIPYALIVGQLGSTFKEGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLAQ
                     KPQAILIALGWALKGDGSLIKEYTVVALQGLTLALFVFFMWVASRGMKSLKVVGSVAG
                     IAMFIMSILYVVMAVTAPAITNVEIATANITWQSFIPHIDFTYITTISMLVFAVGGAE
                     KISPYVNQTRNPGKEFPKGMLFLAVMVAVCAILGSLAMGMMFDSRHIPDDLMTNGQYY
                     AFQKLGEYYHMGNSLMVIYAIANTLGQIAALVFSIDAPLKVLLGDADSKYIPQRLCRT
                     NASGTPVNGYLLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFI
                     AVIRLAQKYKPEYVFIRNRALALTVGIWCFAFTAFACLTGIFPKMEAFTPEWAFQLTL
                     NIVTPFVLVGLGLIFPLLARRNT"
     gene            complement(12842..13618)
                     /gene="pflA"
                     /locus_tag="OPY25_003468"
     CDS             complement(12842..13618)
                     /gene="pflA"
                     /locus_tag="OPY25_003468"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HCS0928986.1"
                     /translation="MTNESVAVTADKKPVIGRIHSFESCGTVDGPGIRFITFFQGCLM
                     RCLYCHNRDTWDTHGGKEITVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRD
                     WFRACKKEGIHTCLDTNGFVRRYDPVIDELLDVTDLVMLDLKQMNDEIHQNLVGVSNH
                     RTLEFAQYLSKKNVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELG
                     KHKWVAMGEEYKLDGVKPPKKETMERVKGILEQYGHKVMY"
     gene            14212..14730
                     /locus_tag="OPY25_003469"
                     /pseudo
     CDS             14212..14730
                     /locus_tag="OPY25_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459947.1"
                     /note="involved in bacterial survival in the host cell;
                     involved in macrophage replication and filament formation;
                     frameshifted; incomplete; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island 1 protein SopD2"
BASE COUNT         3464 a         3549 c         4013 g         3704 t
ORIGIN      
        1 gcagtaccag cagccgcagc aaccgacagc gccgcaagac agtctgatcc acccgctgtt
       61 gatgcgtaac ggcgacagtc gtccattgca gcgtccgacg acgccgctgc cttcattaga
      121 tcttctgacg ccgccgccga gcgaagttga accggtagat acctttgcgc tggaacaaat
      181 ggcgcgtctg gttgaagcgc gtctggcgga tttccgcatt aaagctgatg tggtgaacta
      241 ttcgccaggc ccggtcatta ctcgctttga actgaatctg gccccgggcg ttaaagcagc
      301 gcgtatctcc aacctttccc gggatctggc gcgctccttg tcaacggtag ccgtacgcgt
      361 tgtggaagtc attccaggca aaccttacgt agggttggaa ttgccgaaca agaaacggca
      421 aaccgtttat ctgcgcgaag tgttggataa cgccaaattc cgcgagaatc cgtcgccgct
      481 taccgtggtg ttaggtaagg atatcgcggg cgatccggta gtggcggatc tggcgaaaat
      541 gcctcacctg ctggtggccg gtacgaccgg ttccggtaag tcggtcgggg ttaacgccat
      601 gatcctcagt atgctgtata aagcgcagcc ggaagacgtt cgctttatca tgatcgaccc
      661 gaaaatgtta gaactctcgg tctatgaagg tataccgcat ctgctgacgg aagttgttac
      721 cgatatgaaa gacgcagcta acgcgttacg ctggagcgtc aatgagatgg agcgtcgcta
      781 taagctgatg tccgcgctcg gcgtgcgtaa tctggctggt tataacgaga aaatcgccga
      841 agcggcccgc atgggacgtc cgattccgga cccgtactgg aagccgggcg acagtatgga
      901 tgttcagcat ccggttctgg aaaaactgcc gtatatcgtg gtactggttg atgaatttgc
      961 cgacctgatg atgaccgtcg gtaaaaaagt tgaagagctg atcgcgcgtt tggcgcagaa
     1021 agcgcgcgct gcggggattc acctggtact ggcgacgcag cgtccgtcgg tcgatgtgat
     1081 tactggttta attaaagcca acattccaac ccgtatcgct tttacagtat ccagcaagat
     1141 cgactcccgc accattcttg atcagggtgg cgctgagtcg ttattgggaa tgggggacat
     1201 gctctattcc ggaccaaact ccaccatgcc ggtacgtgtc catggggcgt ttgtgcgtga
     1261 ccaggaagtc catgcggtgg tgcaggactg gaaagcgcgc ggtcgtccgc aatatgtgga
     1321 tggcattacc tccgacagcg aaagcgaagg tggcggtggc ggttttgacg gcggcgaaga
     1381 attagatgcg ctattcgatc aggccgttaa tttcgtcact cagaagcgaa aagcgtccat
     1441 ttccggcgtt cagcgtcagt tccgtatcgg ctataaccgt gcggcgcgta ttatcgaaca
     1501 gatggaagcg cagggtattg tcagcgctca ggggcataac ggtaatcgcg aagtgttggc
     1561 tccgccgcct tttgagtaaa cctgtaaacc ggatggcgct gttcagaggc tgccatccgg
     1621 caacaaaatt cagtattttc ttctttcctc atgctgattt ttggcctgga atagaaagca
     1681 aaaggagctc ctggtcggga gtgtcgaaac ttgaggaata atgatgaaaa aaatggcaat
     1741 cgcctgtgca ttactttcaa gcgttgtagc cagcagcgta tgggctgacg ccgccagctc
     1801 tctgaaaagc cgtctggata aagtgagcag ctttcatgcc acctttactc aaaaagtcac
     1861 cgatggcagc ggtgccgcgg tgcaggaggg acagggtgat ttatgggtta agcggccaaa
     1921 tctattcaac tggcatatga cgcaacctga cgagagtatt ctggtttctg acggcaaaac
     1981 gttatggttc tataacccgt ttgtagaaca ggctaccgcc acgtggttga aagatgccac
     2041 cggaaataca ccgtttatgc tgattgcccg caaccaggcc agcgactggc agcagtataa
     2101 tattaagcag gatggcgata attttgtgct gacgccgaaa gccagcaacg gcaatctgaa
     2161 acagttcacc atcaatgtgg gacgcgacgg gactatccac cagtttagcg ccgtagaaca
     2221 agacgatcag cgtagcgcct atcagctaaa atcccagcaa aacggcgctg ttgaaccgtc
     2281 aaaatttacg tttactccgc cgcaaggggt aacgatagac gaccaacgta agtagaggcg
     2341 atgagtgagc aatctgtcgc tcgatttttc tgataatacg tttcaaccgc tggccgcgcg
     2401 aatgcggccg gaaaatttag cacagtatat cggccagcag catttgctgg ccgcaggtaa
     2461 gccgttgcct cgcgctattg aggccgggca tctgcactcc atgattttat gggggccgcc
     2521 agggacgggg aaaaccacgc tcgctgaagt gatcgcccgc tacgccagcg ccgatgtcga
     2581 gcgtatttcc gccgtcactt ctggggtaaa agagattcgc gaagctatcg agcgcgcccg
     2641 ccagaatcgt aatgccggtc gccgtaccat cctgtttgtc gatgaagtgc atcgctttaa
     2701 caaaagccag caggacgcct ttttaccgca tatcgaagat ggcactatca cctttatcgg
     2761 cgcgaccacg gaaaatccct cttttgagct gaactcggcg ctattgtcgc gagcgcgagt
     2821 ctatctgctg aaatcgttga ctactgacga tattgagcaa gtactggacc aggcgatgca
     2881 ggacaaaacg cgtggttacg gcgatcagga tatcgtgtta ccggatgaga cacggcgagc
     2941 gattgctgag ctggtcaatg gcgacgcgcg gcgcgcctta aatacgctgg aaatgatggc
     3001 tgatatggcg gaggcggatg acagcggcaa acgcgtttta ttgcccgcct tgttgaccga
     3061 gatcgccggc gagcgcagcg cgcgttttga taacaaaggc gatcgcttct acgatcttat
     3121 ttccgcctta cataaatcag tgcgcggcag cgcgccggat gccgccctct attggtatgc
     3181 ccgtatcatt accgcgggag gcgatccgct gtacgtggcg cgtcgctgcc tggcgattgc
     3241 ctcggaagat gtgggtaatg ccgatcctcg cgcgatgcag gtcgccattg ccgcgtggga
     3301 ttgtttcacc cgcgtcggcc cggctgaagg cgaaagggcg atcgcgcagg ctatcgttta
     3361 tctcgcctgc gcgccgaaga gcaacgccgt ctataccgcc tttaaggctg cgctggccga
     3421 cgcgcgcgaa cgtcctgatt atgacgttcc tgtccatctg cgtaatgcgc caaccaaact
     3481 gatgaaagag atgggctatg gccaggaata ccgctatgcc cacgatgagc ccaatgccta
     3541 tgctgcgggt gaagtgtact tcccgccgga aatcgcgcaa acgcgctatt atcatccgac
     3601 aaatcgtggt ctggaaggta agattggcga aaagctcgcc tggctggctg aacaggatca
     3661 aaatagcccc acaaaacgct accgctagtg taaacgttgc ggtaaggtta tctctaaata
     3721 tgatgctcca ggtatcatgg cgttgatgat gaacctcgtt atgcctgata gcacgttgct
     3781 tatgaggtcc gcgggtatag cgcaatggat gcgttgttgc tgtcgtcggt caggtaaggc
     3841 gaaaacgtcg ctattacgta aacggggttt acgttcatca atacaatcag aggcgatcat
     3901 caattgatcg cgtttccttt tattattcga taagcacagg ataagcatgc tcgatcccaa
     3961 tctgctgcgt aatgagccag acgcagtcgc tgaaaaactg gcacgccggg gctttaagct
     4021 ggatgtagat aagctgcgcg ctcttgaaga gcgtcgtaaa gttttgcagg tcaacacgga
     4081 aaacctgcag gcggagcgta attctcgatc gaaatccatc ggccaggcga aagcgcgcgg
     4141 ggaagatatc gagcctttac gcctggaagt gaataaactg ggcgaagagt tggatgcggc
     4201 gaaagccgag ctggatacct tgctggcgga gatccgcgat atcgcgctga ccatcccaaa
     4261 cctgcctgcg gatgaagtgc cggtaggtaa agatgaaaac gacaacgttg aagtcagccg
     4321 ctggggtacc ccgcgtgagt ttgattttga aatccgcgat cacgtcacct taggggaaat
     4381 gcactccggc ctcgactttg ccgctgcggt taagctgacc ggctcccgct ttgtggtgat
     4441 gaaaggacag attgcgcgta tgcatcgcgc attgtcgcag ttcatgttgg atctgcatac
     4501 ggaacagcac ggctatagcg aaaactacgt gccgtatctg gttaaccacg acacgctgta
     4561 tggcaccggt caactgccga aattcgcagg cgacttgttc catacccgtc cgctggaaga
     4621 agaagcagac agcagtaact atgctttgat cccgacggcg gaggttccgc tgaccaatct
     4681 ggtacgcgat gaaatcatcg acgaagatca gctgccgatt aaaatgacgg cgcatacgcc
     4741 ttgtttccgt tctgaagcag gttcttatgg tcgtgatacc cgcggcctga ttcgtatgca
     4801 tcagtttgac aaagttgaga tggtgcagat cgttcgcccg gaagattcta tggctgcgtt
     4861 ggaagagatg accggccacg cggaaaaagt gctccagcta ctgggactgc cataccgtaa
     4921 aatcattctg tgcactggcg atatgggctt cggcgcctgc aaaacttatg acctcgaagt
     4981 ctgggttccg gcgcagaata cctaccgcga gatctcttcc tgctctaacg tctgggactt
     5041 ccaggcgcgt cgtatgcagg cacgctgtcg cagcaagtcc gacaaaaaga cccgtctggt
     5101 ccataccctg aatggttctg gtctggcggt aggtcgtacc ctggtggctg tgatggaaaa
     5161 ctatcagcag gctgatggtc gtattgaagt gccggaagta ttacgtccgt acatgaacgg
     5221 actggaatat atcggctaat cctcgctttc tcctcttcta aaaagcgcct gcgggcgctt
     5281 tttttatgcc agtttgatac cggacaataa tccctaccct attaggggta atactgattt
     5341 cgaatgaagg tcagttttta acgctatttt tctacttttt cgatatatat cagactttat
     5401 agcgacgtta tcgctatata aaattctata catcgtttta ttgctttttt attgtgagca
     5461 gcagagtgag cccttatgaa aactaagatc cctgatgccg tgctggcagc cgaggtgagc
     5521 cgtcgtggtt tagtcaaaac caccgcgata ggcggcctgg cgatggccag tagcgcattt
     5581 accctgccat ttacccgcat cgctaacgcc gcagaggcga taagcccgac gaaaaccgac
     5641 gagaaagtcg tctggagcgc ctgtacggta aactgtggca gccgttgtcc gctacgtatg
     5701 catgttgtgg atggcgaaat caaatatgta gaaacggata ataccggaaa cgatgattac
     5761 gatggcctgc accaggttcg cgcctgcctg cgcggtcgtt ctatgcgtcg tcgcgtctat
     5821 aacccggatc gtctcaagta tccgatgaag cgcgtcggcg cgcgcggcga aggtaaattt
     5881 gagcgtatta gctgggacga agcctacgat atcattgcca ccaatatgca gcgtcttatc
     5941 aaagagtatg gcaacgagtc catttatctg aactatggca cgggaacgct gggcggcact
     6001 ttgacacgtt catggccgcc gggaaaaacg ctggtcgctc gtctgatgaa ctgctgcggc
     6061 ggttatctta atcactacgg tgattactct tccgcgcaaa tcgcagcggg tctgaattac
     6121 acctatggcg gctgggcgga tggcaatagt ccatccgaca ttgaaaacag taagctggtg
     6181 gtgttgtttg gtaataaccc tggcgaaacc cgcatgagcg ggggcggtgg aacgtattat
     6241 cttgaacagg cgcggcagaa atcaaacgcg cggatgatca ttatcgatcc tcgttacacc
     6301 gacaccggcg ccggtcgcga agatgagtgg attccgattc gtccaggtac cgatgcggcg
     6361 ctggtcaatg gtctggcata tgtcttaatc accgagaaca tggtcgatca gccgttcctg
     6421 gataaatatt gcgtcggtta tgacgaaaaa accttgcctg ccagcgcgcc gaaaaacggt
     6481 cactacaaag cctatattct gggcttgggt aaagacggta tcgcaaagac gccggagtgg
     6541 gcggcgcaaa ttaccggtat tccggcagat cgcattatta aactggcgcg agaaatcggc
     6601 agcgctaaac ccgcctatat ttgccagggg tgggggccac aacgtcatgc taatggagaa
     6661 atcgccacgc gcgccatctc gatgctggcg atcctgacgg gtaatgttgg gattaacggc
     6721 ggtaacagcg gcgcgcgcga agggtcttat gccctgccat ttgaacgtat gcccacgttg
     6781 gaaaatccgg ttgaaaccag catctccatg tttatgtgga ccgatgccat tgaacgcggc
     6841 ccggaaatga cagcgctgcg tgatggcgtg cgggggaaag ataagctgga cgtgccgatc
     6901 aaaatgatct ggaactatgc tggcaactgt ttgattaacc agcactctga gattaaccgc
     6961 acccacgaaa tcctgcagga tgacagtaaa tgtgaaatga tcgtcgttat cgactgtcat
     7021 atgacctcgt cggcaaaata cgccgatatt ctgttgcctg attgcactgc ttctgagcag
     7081 atggactttg cgctggatgc ctcctgcggg aacatgtctt acgttatctt cactgaccag
     7141 gcgattaaac cgcgcttcga gtgtaagacg atttatgaga tgaccagcga actggcgaaa
     7201 cgtcttggcg tggaacaaca gtttaccgaa ggccggacgc aagaagagtg gatgcgtcat
     7261 ctgtacgaac agtcgcgtaa atccattccg aatctgccca cctttgagga gttccgtaag
     7321 caaggcatct tcaaacagcg cgaccccgaa ggccaccatg tcgcctataa agacttccgc
     7381 gaagatccgc aagcgaatcc acttacaacg ccatcgggca agattgaaat ctattcacag
     7441 gcgttggcgg atatcgccgc cacctgggag ctgccggaag gcgacgtgat cgatccatta
     7501 ccgatctaca cgctaggttt tgaaaactat aacgatccgc taacggataa attcccgctg
     7561 cagttgacgg gtttccacta taaagcgcgt gtgcattcca cttatggcaa cgtagacgta
     7621 ctgaaagccg cctgtcgcca ggaaatgtgg attaacccaa tggatgcgca gaaacgcggt
     7681 atcaacaatg gcgataaagt ccgcatcttc aacgatcgcg gcgaagttca tatcgaggct
     7741 aaagtgacgc cgcgcatgat gccgggcgtg gtcgctctgg gagaaggcgc atggtatgac
     7801 ccggatgcaa aacgcgtgga tcagggcgga tgtattaacg tactgaccag tcaacgtcct
     7861 tctccgctgg cgaaggggaa cccgtcacat acgaacctcg ttcaggttga aaaggcgtaa
     7921 ggagtaaccg atgacaaccc agtatggatt ttttattgat tccagccgtt gcaccggttg
     7981 caaaacctgc gaactggcct gcaaggacta caaagatttg accccggatg tcagcttccg
     8041 ccgcatttat gagtatgcag gtggcgactg gcaggaggat aacggcgtct ggcaccagaa
     8101 cgtctttgcc tactatctct ccatctcctg taaccactgc gaagacccgg cctgcaccaa
     8161 agtctgcccg agcggcgcga tgcacaagcg cgatgacggt tttgtggtgg tgaacgaaga
     8221 ggtctgtatc ggttgccgct actgccacat ggcctgcccg tacggcgcgc cgcagtacaa
     8281 cgcggccaaa ggtcatatga ccaagtgcga tggctgttat gaccgggtgg cggaaggtaa
     8341 gaaaccgatc tgcgtcgaat cctgtccgct gcgggcgctg gatttcggcc cgatagacga
     8401 actgcgcaaa aaacacggtg agctggctgc cgtcgcgccg ttgccgcgcg cgcatttcac
     8461 gaagccgaat attgtgatta aacccaacgc caacagccgc ccgaccgggg acaccaccgg
     8521 ttatctggcc aatccgaagg aggtataaga tgggaagtgg atggcatgaa tggccgttga
     8581 tgatcttcac ggtctttggt cagtgcgtgg ccggtggttt tattgttctg gctctggcgc
     8641 tgatgaaggg cgacctgcgc gcggaaacgc agcagcgggt gatcgcctgt atgtttggtc
     8701 tgtgggtgct gatggggatt ggctttatcg cctcgatgct gcatctgggc tcgccgatgc
     8761 gcgcgtttaa ctcgcttaac cgcgtgggtg cttccgcact gagcaatgaa attgccagcg
     8821 gctcggtgtt ttttgcggtc ggcgggatcg gctggctgct ggcggtactg aaaaagctgc
     8881 cgccggcact gcgcacactc tggctgatta tcacgatggt actgggcgtc gtcttcgtct
     8941 ggatgatggt acgcgtctat aacagcatcg atacagtacc gacctggtat agcgtctgga
     9001 cgccgctggg cttcttcctg acgctcttta tgggtggccc gctactgggt tatctgctgc
     9061 tgcgcatcgc gggcgtgaac ggttgggcga tgcgtctgtt gcctgcggtt tcggtgctgg
     9121 cgctggtggt tattgccatt atggtggcca tgcagggcgc ggaactggcg acgattcaca
     9181 gttccattca gcaggcgtct gctctggtgc cggattatgg ttcgctgatg gcctggcgta
     9241 tggtgctgct tgcggcggcg ttgtgctgct ggattgtgcc acagttaaaa gggtatcaac
     9301 ctgcggtacc gttactctct gtcgccttca ttctgatgct ggcgggggaa ttgattggcc
     9361 gcggcgtatt ctatgggctg catatgaccg tgggcatggc ggtagccagc taacgcgttg
     9421 acgcgcattc ggcctgcaga acgtgcaggc cgaatacgcc tttagccgcc gtcaatctaa
     9481 ggaatataac cggggcggag aaggcgcata taaatccata gagaagaaaa cgaagctaaa
     9541 ggaaccatga aatttttcga ctgaacaaaa cgccgatttt gcgggttaga tcaataaaaa
     9601 caaggggatg aatttttagc ctttcaatat attcacgtgc agaataagta aatcgaatcg
     9661 atagtctcaa aacttgcgga tcgcccatgc ggagccgatt gacaatgttt ttggcgatgg
     9721 catgatgcgc atgaaatttg aacttcctca cggtttttat tcatgtccat ctatacccgt
     9781 cccgtcatgc ttttgctgtg cgggctactt ttgttgaccc tggccattgc ggtactgaat
     9841 acgcttgtgc cgctgtggct tgctcaggca aaccttccga cctggcaggt ggggatggtc
     9901 agctcgtctt attttaccgg caatctggtc gggacgttat ttaccgggta tttaattaaa
     9961 cgcattgggt ttaaccgtag ctattatctt gcctcgctga tcttcgccgc gggttgtgtc
    10021 gggttggggg tgatggtggg gttctggagc tggatgagct ggcgttttat tgccggtatc
    10081 ggctgcgcca tgatttgggt ggttgtcgaa agcgcgttga tgtgcagcgg aacctcgcat
    10141 aatcgcggac gcctgctggc tgcctatatg atggtctatt acatggggac cttccttgga
    10201 caattattgg tcagtaaagt atctggtgaa ttgctgcacg tccttccctg ggtgaccgga
    10261 atgattctgg cgggaattct gccgctactc tttacccgaa ttgtaaatca gcaaacgcag
    10321 gcacgtcatt cctcttctat tagcgccatg ctgaagctac gccaggcgcg tcttggcgtg
    10381 aatggttgta ttatttccgg cattgttctt ggttcattat atggcctgat gccgttatat
    10441 ctgaagcatc aggggatggc taacgccagc atcggtttct ggatggcggt gctggtgagc
    10501 gccggtattt tggggcaatg gccaatggga cgtctggcgg acaaatttgg tcgcttgctg
    10561 gtattacgcg tacaggtatt cgttgtcata ctcggcagta ttgccatgtt aacccaggcg
    10621 gcgatggcgc cagctctgtt tattctgggg gcggcgggtt ttacgcttta tcccgttgca
    10681 atggcctggg cctgtgaaaa agtcgaacac caccagcttg tggcaatgaa ccaggcgctg
    10741 ttgttaagtt atacggtagg gagcctgttg gggccgtctt ttgctgcgat gttaatgcag
    10801 aattattcag ataatctgct gtttattatg atcgccagcg tatcgtttat ttatctgctg
    10861 atgctgttac gtaacgtcgg ccagacgcct aatcctgtcg cccacatcta actgttctct
    10921 gaatcgtatg caggacgtga gtcttgcata ctctttgttt atgttttacg taaaataatt
    10981 gacctgcata attttcttgc tttactgaaa aataaaatgt gccgaaggtt ataattttgc
    11041 gctcctctat tttctctctt cgtctttacc gcgcataatc ccccgcttca tttatagtaa
    11101 tagcattgtg ttcacgaagg atcgcgttat gccgaatgtg caggaaaaac agttgcgatg
    11161 gtacaacatc gccctgatgt cgtttattac cgtttgggga ttcggcaatg ttgtcaataa
    11221 ctatgctaac caggggttag tggttgtctt ctcctgggtg tttatttttg cgctctattt
    11281 tattccttat gccttaatcg tggggcaact gggctcaacc ttcaaagagg gaaaaggggg
    11341 cgtcagtacc tggattaagc atacgatggg gccggggttg gcttaccttg cggcatggac
    11401 ttattgggtc gtgcatattc cctacctggc gcaaaagccg caggcgatac tcattgcatt
    11461 gggatgggct ttaaaaggcg acggctcgtt gataaaagaa tataccgtcg ttgccttgca
    11521 ggggctgacg ctggcattgt ttgttttctt tatgtgggtt gcttcccggg ggatgaaatc
    11581 gctaaaggtt gttgggtctg tggctgggat tgccatgttt atcatgtcaa ttttatatgt
    11641 tgtgatggca gtgaccgcgc cagcaattac aaacgttgaa attgcgaccg ctaacatcac
    11701 ctggcagtca tttattcctc atatcgattt tacctatatc accaccatct ctatgttggt
    11761 ctttgcggtt ggtggggcag agaagatctc gccttatgtc aaccagacgc ggaatccagg
    11821 aaaagaattt ccgaagggga tgctcttttt agccgtcatg gttgcggtct gcgctatcct
    11881 cggttcgttg gcgatgggaa tgatgtttga ttcccggcat atacctgacg atttaatgac
    11941 caatgggcaa tattatgcat tccagaaatt gggtgagtat taccatatgg gtaattcatt
    12001 aatggtgatt tatgccattg ccaatactct ggggcaaatc gccgcgctgg tgttttctat
    12061 tgatgcgcca ctgaaagtct tactgggtga tgcagacagt aaatatatcc cgcagcgctt
    12121 atgtcgtact aacgcttcag gtacaccagt taacggttat ttgctgacat tagtgttggt
    12181 cgctatcttg attatgttgc caacgcttgg catcggcgat atgaacaacc tgtacaaatg
    12241 gctgcttaat ctcaattcag tcgttatgcc gctgcgctat ctgtgggtat ttgtcgcctt
    12301 tattgccgtc attcgactgg cgcaaaagta caaacccgaa tatgtgttta ttcgcaaccg
    12361 ggcgttggcg ttaactgtgg gaatatggtg ttttgccttc accgcgtttg cctgccttac
    12421 cggtattttc cccaaaatgg aggcgttcac gccggagtgg gcattccagc tgacgttgaa
    12481 catcgtgaca ccttttgtcc tggtcgggtt gggattaatt ttcccactgc tggcgcgtag
    12541 aaacacataa cgacgctctt ttccacggcg ctcctgtcag gcgagcgcct tttaaggtta
    12601 caggtgcctg ggttccaggc ggagaccacg gtattaacag gcgccggggc agcaatagtt
    12661 gtcagacctt caacccagca gcagataagc gactctgtat ttaatacctg gtaagcgcaa
    12721 tattgttaac caggcctgtc tgacggcggg gtcgggtatt ttagcggtaa gagcgttacc
    12781 cagacagcaa aacggctacc gtcatgggta gccgtttaaa agcggataag atagcaggcg
    12841 attaatacat cactttatga ccatactgct caagaatacc ctttacacgt tccatggtct
    12901 cttttttagg cggcttcacg ccatccagtt tatattcttc gcccattgcc acccatttat
    12961 gtttgcccag ctcatgatag ggcagcagtt cgattttttc gacattaccc atatcgcggg
    13021 taaactcacc caggcgatgc gcggaatcat cgtcgtcaga ccagccggga acgacaacgt
    13081 aacggatcca gaccttcaca tttttctttg ataaatactg cgcgaattcc agcgtccggt
    13141 gattggatac accgaccaga ttctggtgga tctcatcatt catctgcttg agatcgagca
    13201 tcaccagatc ggtaacgtcc aacagttcat caatcaccgg gtcataacgg cgcacaaagc
    13261 cgttggtgtc gagacaggtg tggatacctt cttttttaca ggcgcgaaac cagtcgcgta
    13321 caaattctgc ctgcaaaatg gcctcgccgc cggatgccgt cacgccgccg ccagaagcat
    13381 tcataaaatg ccgataggtc accacctctt tcattaagtc ttcaacggtg atttctttac
    13441 cgccatgcgt atcccatgtg tcgcggttat ggcaatacag gcagcgcatc aggcagccct
    13501 ggaaaaaggt aataaagcgg atgcctgggc catcaacggt gccacaggac tcaaaggagt
    13561 gaatgcgacc aataaccggc tttttatcag cagttactgc aacactttca tttgtaatac
    13621 aatcggttaa gttactcata tcgcttcggc tagctctaaa taacatgggg tttatggaca
    13681 cattccgggc atgttgagca ccctagtaag ggggttgcat cctgtaaaaa agcggtactg
    13741 cgagcgtaaa ttttggacta cagaatgtgt ggctgttcca gaatgtgctg caatggagct
    13801 attttacctc tattcagtat aaaatatacg gcaaatctat gctgcatagc ttgcaccgcc
    13861 agaaattgtg gctcattcat cagctcgtaa cgcccgaacc gcaatacata ctgtaagtgt
    13921 atcatccata gcgtcctggt tttgctgttt atgaaccgcc tcttttttca aatggttgat
    13981 gccgtttttg tggtcagaac aaaaataatt ctcaacataa ttcagatgtg tccaaagaac
    14041 gttacgcctg tccagtgcct ggcgttgcat tcaacgcgca atcaggtgta aatctgatgt
    14101 catttctaaa cccggactga ttcaatctct taaatagagt gtggttttaa tcaaaaaatg
    14161 agagcaacgg attggatttt gctttcgcgg taaataatca aaggagttat tatgccagtt
    14221 acgttaagtt ttggtaatcg tcataactat gaagttaata cttcacggct aacccgtttg
    14281 atgagtccta ataaagaaga agcgctatac atgggggtat gggatagatt taaggactgc
    14341 ttcagaacac acaaaaaaaa gaggtgctgg aggtattata tacactcatc catggatgtg
    14401 aacgtgaaaa tcaagctgaa cttaatgttg atataaccgg catggagaag atacatgcct
    14461 ttacacaatt aaaacaatat gctaatccat ctcaacaaga gcgctttgtt atgcgttttg
    14521 atatgaatca gacaaaagtt ttatttgaga ttgatggcca ggttattgat aaatgtaatt
    14581 tgcatcgtct cctcaacgtt tcagaaaact gtatttttag agtgatggaa gacgatgaag
    14641 tagagttgtt ttttaaagta tgtattaagt atggagaaaa aattgctcgc tatccagaat
    14701 tattagaagg ctttgctaat aaacttaaag
//
LOCUS       DAJVKX010000116        14502 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.116, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000116 DAJVKX010000000
VERSION     DAJVKX010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14502
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.116"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(198..560)
                     /locus_tag="OPY25_003470"
     CDS             complement(198..560)
                     /locus_tag="OPY25_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HCS0928987.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQAGLSLVESADKYAELEKEKET
                     LEAEIIRLREVHSQKLSKEAQKLMNLPFRRAITKKEQADMGKLKKSVRGLIVVHPMTA
                     LGREMGLKEMTGFAKSEF"
     gene            851..1057
                     /locus_tag="OPY25_003471"
     CDS             851..1057
                     /locus_tag="OPY25_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0928988.1"
                     /translation="MAKIGENVPLLIDKAVDFMASSQAFREYLNKTPPRDYVPSEVPS
                     ESTPIYLQRLEYYRRLYRPKEERG"
     gene            complement(1067..1657)
                     /gene="mtlR"
                     /locus_tag="OPY25_003472"
     CDS             complement(1067..1657)
                     /gene="mtlR"
                     /locus_tag="OPY25_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HCS0928989.1"
                     /translation="MTQNPAQVSLRPNNRLSDMQAIMEQTQAFENRVLERLNAGKTVR
                     SFLITAVELLTEAVNILVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGV
                     LSRTEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVMALPPPPHFDTSDAA
                     LYAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(1654..2802)
                     /gene="mtlD"
                     /locus_tag="OPY25_003473"
     CDS             complement(1654..2802)
                     /gene="mtlD"
                     /locus_tag="OPY25_003473"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCS0928990.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGENEQVDTVSGVNAVSSIGDDVVDLIAHVDLITTAVGPVVLERIAPAIAKG
                     LVKRKAQGVDAPLNIIACENMVRGTTQLKGHVMNALADGDKAWVEQHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEGIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHVNLVKGIAAAMHF
                     RSDEDPQAQELAALITEKGPQAALAQISGLDANSDVVAEAVNAYNATK"
     gene            complement(3023..4939)
                     /gene="mtlA"
                     /locus_tag="OPY25_003474"
     CDS             complement(3023..4939)
                     /gene="mtlA"
                     /locus_tag="OPY25_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCS0928991.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGRLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGYCIKKFDSWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKI
                     LAAGVNFMVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHEMGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAIVAAMAVSFVVSAILL
                     KTSKVKEEDDIEAATRRMHDMKAESKGASPLAAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKVQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHNTNEEKVRDHLKDSFEEGDNNLFKLGAENIFLGRKAA
                     NKEEAIRFAGEQLVKGGYVEPEYVEAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGKKA"
     gene            5414..6022
                     /locus_tag="OPY25_003475"
     CDS             5414..6022
                     /locus_tag="OPY25_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HCS0928992.1"
                     /translation="MKLIGSYTSPFVRKISVLLLEKGITFEFINELPYEADNGVAQYN
                     PLGKVPALVTEKGEYWFDSPIIAEYIELLDIAPAMLPRDPMAALKVRQLEALADGIMD
                     AALVSVREQARPAAQQSETELLRQREKINRSLDMLESYLSDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVSRPHLVKLVETLFQRESFARTEAPKA"
     gene            6121..7512
                     /gene="selA"
                     /locus_tag="OPY25_003476"
     CDS             6121..7512
                     /gene="selA"
                     /locus_tag="OPY25_003476"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HCS0928993.1"
                     /translation="MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRML
                     DDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQ
                     EAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNEN
                     TGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEP
                     MPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLS
                     QIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRC
                     LEDESRFMEMMLK"
     gene            7509..9359
                     /gene="selB"
                     /locus_tag="OPY25_003477"
     CDS             7509..9359
                     /gene="selB"
                     /locus_tag="OPY25_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HCS0928994.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGINADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVLGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLQILQLT
                     GNLQLTVALTKADRVDEARISEVREEVLAALDNYGFADTVLFVTAANEGRGIAELRAH
                     LQQLPARLHAAQHRFRLAIDRAFTVKGAGLVVTGTALSGEVNVGDTLWLTGVNTPMRV
                     RSLHAQNQPTDHAYAGQRIALNIAGDAEKEQLNRGDWLLSDAPAGEAFSRVIVSLALH
                     APLSQWQPLHIHHAASHVTGRVSLLEGALAELIFDTPLWLADNDRLVLRDISARATLA
                     GARVVTLNAPRRGKRKPDYLHWLSTLADAQDDSAALAIHLERGAVNLPDFGWARQLNP
                     LGMRQLIEQHGFIQAGDNLLSAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMA
                     LPMEDEALVLMLIERMRDEGLIHSHHGWLHLPDHKAGFSDEQQAVWQKVEPLFGDEPW
                     WVRDLAKETGTEEQLMRLVLRQAAQQGIITAIVKDRYYRNDRIVAFANMIRELDQERG
                     STCAADFRDRLNVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPQKE"
     gene            complement(9644..10525)
                     /locus_tag="OPY25_003478"
     CDS             complement(9644..10525)
                     /locus_tag="OPY25_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCS0928995.1"
                     /translation="MQQYIGIDVGGTHVKYGVINSDGEELTHHQFDTPEDASTFTRKW
                     QDVVARCQQDYDIAAIGVSFPGHINPHNGHAAKAGALAYLDDVNLMELFSGLTDLPLV
                     VENDANCAALGEMWRGAGQHYDNLVCITIGTGIGGGIIVGRELYRGAHFHAGEFGVMP
                     VGNNGESMHKIASTSGLMASCRQALALPAEEMPPADVIFERMATDVHLREAVNDWARY
                     LSRGVYSVISMFDPGVVLIGGGISEQEKLYPLLTRHLETFEMWEALQVPIQPCQLGNQ
                     AGRLGAVWLAQQKLDRR"
     gene            10694..12232
                     /gene="aldB"
                     /locus_tag="OPY25_003479"
     CDS             10694..12232
                     /gene="aldB"
                     /locus_tag="OPY25_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HCS0928996.1"
                     /translation="MTNNPPSTRIQPSEYGYPLKLKARYDNFIGGDWVAPADGEYYQN
                     LTPVTGQPLCEVASSGKKDIDLALDAAHKAKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADIPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEVIGDLLPPGV
                     VNVVNGAGGEIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSGTQMGAQVSHGQLETILNYIDIGKKEGADILTGGRRKELDGELKEGYYLE
                     PTILFGKNNMRVFQEEIFGPVLAVTTFKTMEKALEIANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(12350..14305)
                     /locus_tag="OPY25_003480"
     CDS             complement(12350..14305)
                     /locus_tag="OPY25_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
                     /protein_id="HCS0928997.1"
                     /translation="MNVLEVDLHKLTVSDPLLGQYQQLVRDVVIPYQWDALNDRIPEA
                     EPSHAIENFRIAAGQQTGDFYGMVFQDSDVAKWLEAVAWSLCQKPDPELEKTADEVIE
                     LVAAAQCDDGYLNTYFTAKAPQERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLD
                     VVCRLADHIDSTFGPGENQLHGYPGHPEIELALMRLYEVTEQPRYMTLASYFIGQRGA
                     QPHFYDEEYEKRGQTSYWHTYGPAWMVKDKAYSQAHLPISQQQTAIGHAVRFVYLMTG
                     VAHLARLSNDEGKRQDCLRLWKNMAQRQLYITGGIGSQSSGEAFSSDYDLPNDSVYAE
                     SCASIGLMMFARRMLEMEADSQYADVMERALYNTVLGGMALDGKHFFYVNPLEVHPKS
                     LKFNHIYDHVKPIRQRWFGCACCPPNIARVLTSIGHYIYTPRADALYINMYVGNSMEI
                     PVENGALKLRISGNYPWHEQVKIAIDSVQPVRHTLALRLPDWCPEAKVTLNGLEVEQD
                     IRKGYLHIRRTWQEGDTISLTLPMPVRRVYGNPLARHVAGKVAIQRGPLVYCLEQADN
                     GEELHNLWLPKESEFRVFEGKGLFAHKMLIQAEGEKQSAADAQHQALWHYDNAPSSRQ
                     PQTLTFIPWFSWANRGEGEMRIWINER"
BASE COUNT         3287 a         3882 c         3946 g         3387 t
ORIGIN      
        1 gatgaaaaaa ttcattgtat aaatacaaac aggcacgata gtggaatttt ttatcctgaa
       61 aaagcaggga ttgccgttaa aaatgaactt gtatataaac gatgtaaata cttctaggaa
      121 aaattcggaa tatagcccga tgcattcaag acaccctccg tacaacgggt gtcttgagag
      181 cctgggatgc ggaaggttta gaactcgctc ttcgcgaaac ctgtcatctc tttgagtccc
      241 atttcccggc ccagcgccgt catcgggtgc actacgatca gaccacgcac gcttttcttc
      301 aacttgccca tatcggcctg ctctttttta gtgatagcgc ggcgaaacgg caggttcatc
      361 agcttctgcg cttctttact cagtttctgg ctgtgtactt cgcgcagacg gataatttct
      421 gcttccagcg tctctttttc tttttccagc tccgcgtatt tatcggcgga ttcaaccagc
      481 gagagacctg cctgctggtg gcgaatagcg tcaagacgat cgctcaggcg tttaatttcg
      541 tttttttcga cttctttcat gggatagctt ctgatagaaa tgggatagat accctatagt
      601 atgcgcgcag tgggtgattc ttcacaactc atggcgtaac gataatcaat tatggtaaat
      661 attacaccgc taattattta tttatccatt tgaaaataaa gtgctttttt tcgaaagaaa
      721 agatgaaacg cctttttgtc ggcaagaaaa gcaattaagc acattttcct caatgatgac
      781 gctaaatcga tcctaaactc aaataagcgg ccgcgggagt cagacgcgga tcacacatgg
      841 aggatctatc atggcaaaaa taggtgagaa cgtaccactt cttattgata aagccgtcga
      901 ttttatggcg tccagccagg cgttccgtga gtacttgaat aaaacgccgc cgcgtgatta
      961 tgttccttcc gaagtgccgt cggagagcac gcccatttat ttgcagcgtc tggaatatta
     1021 ccggcggctg taccgaccaa aagaagaaag aggttaacgg cgggatttac ttttgaaagg
     1081 ccttttttaa gctgatttta gaaatcagct cggtcagaga gagaaccatc gtcgaacgca
     1141 ccgcctgctg gtagcgctga atttgcatgg cgtatagcgc cgcgtcggat gtatcaaaat
     1201 gtggcggcgg cggcagcgcc atgacgcaat gcagttcgcc aaacggcccg aggatttcat
     1261 cgtcggtaaa ggcgtactca ttgccgtcgt gattcagctc ttcgcgcagc gccattaaca
     1321 gctccgcatc ttcatattcg gtgcggctga gtacgcccag gccatagata agtttcagac
     1381 gtaccgaaag atcgcccagc ggcccgtcgc cgtccagcaa cggttccaca gcgtatttca
     1441 cggcatagtc gtctttgcga aacacctgaa gcaccagaat attcaccgcc tcggtcagta
     1501 actcgacggc ggtaatcagg aagctccgta cggttttgcc agcattcaga cgctcaagca
     1561 cacgattttc aaaggcctgg gtttgttcca ttattgcctg catatctgac aatctgttat
     1621 ttgggcgcag gctaacctgc gccgggttct gcgtcatttg gtcgcgttat atgcgttaac
     1681 cgcctccgcc accacatcgc tattggcatc cagcccggaa atttgcgcca gcgcggcctg
     1741 cgggcctttt tcggtaatca gcgccgccaa ctcttgtgcc tgcggatctt catcgctacg
     1801 gaaatgcatc gccgccgcga tccctttcac cagattcaca tgcggcagac catattccag
     1861 ggtgccaagc agcggtttga tcagacggtc gcccgcgctg agtttgcgta gcggctgacg
     1921 gcctacgcgt tcgacgtcat ctttcagata cgggttttca aaacgaccga ggattttctg
     1981 aatgtatgcc gcatgtttgt cggcatcaaa accgtagcgt ttgatcagca ccgcgccgct
     2041 ttcttccatc gcgcctttca ccaccgcgcg aataccctca tcgagaatgg cgtcgcgaat
     2101 ggtttgatga ccggctaatt tgccgaggta cgcggttata gcatgacctg tgttcagcgt
     2161 gaagagttta cgttcgacaa atgccatcag gttatccgtt aactccatcc ccggaatgtt
     2221 tggcaacgcg cctttaaact gggttttatc gacgatccac tcgctgaagg tttctaccgt
     2281 cacttccagc ggatcgttgg tcgcagaagc agatggcggc acaatacggt caacggcgga
     2341 atcgacaaaa ccgacgtgct gttcaaccca ggctttatcg ccatccgcca gcgcgttcat
     2401 tacgtggcct ttcagctgcg tggtgccgcg caccatattt tcgcaggcga tgatattcag
     2461 cggggcatcc acgccctgcg ccttacgttt taccagccct ttagcgatag ccggtgcgat
     2521 acgctcaagc accaccgggc ccacggcagt ggtgattaaa tcaacgtggg caatcaggtc
     2581 gacaacatca tcgccgatgc tgctgacagc gttgacgccg gaaacggtat ccacctgctc
     2641 attttcaccc acaacatgaa cctgatagct atgacgggca ttcagggcat cgagtacgac
     2701 ctggtttaca tccgcaaacg tcagttgtat ccccgcgtca gccagcaatt tgccgataaa
     2761 gccacgaccg atattacctg cgccaaaatg taatgctttc atagtattaa ccttcattaa
     2821 tgtttttacc cgagagggct ggggtgaggc ttttccctca acctaaccct ctccacaaga
     2881 gagaggatat cgccttcata tttagaactg cagatgcgtt ggctctcctc gctcacccca
     2941 gtcacgtact tatgtacgct cctggggatt cactgcgttg ccgccttcct gcagctcgaa
     3001 ctattttggg gatacttaac tgttaagctt ttttacctgc cagcagttcc agcacttcat
     3061 ccacgctggt ggtgtgcgcc agacgttcga tcacggattc atcatccagc gcgttggtca
     3121 agctggtgat gacctggatg tgctcattgt tacgtgcggc gataccaatg accagacggg
     3181 caatatcgtc ttcttcttca ccgaagcgta cgccttccgg atactggcag aacaccacgc
     3241 cggttttcag cacgcggtct ttagcttcta cggtaccgtg cggtaccgcg atggattcac
     3301 cgaggtaagt cggcgtcagc ttttcgcggt ccagcatcgc ctcgacgtat tccggctcaa
     3361 catagccgcc tttcaccagt tgttcaccgg caaagcgaat cgcctcttct ttgttagcgg
     3421 ctttacggcc caggaagata ttctccgcgc ccagcttgaa caggttgtta tcgccctctt
     3481 caaagctatc tttcagatga tcgcggactt tctcttcatt agtattgtgg cgctgtgcgg
     3541 caaccagacg ttcggtcagg ctggtgtaca ggccgctatc caggaagttg gtcagcgaaa
     3601 tatgctgcgc ctgcggtacc tgacgcatag cacgttcggt caggtcgcgg tgagtaatga
     3661 ccagatccac atccggcggc agattgttaa tggcgctgtt ggtgacggaa atctgagaca
     3721 gacccgcatc ctgtactttc ttacgcagta cccctgcgcc catcgcgctg gaacccatac
     3781 cggcatcgca agctacgatg attttacgca catggctgag gtcattggtg acgtcgccag
     3841 ccgccagcgg agaggcgcct ttagattccg ctttcatgtc atgcatacga cgggtggccg
     3901 cttcaatatc atcttcttct ttcactttgc tggttttcag cagaattgca gacaccacga
     3961 aggagaccgc cattgccgcc acgatggccg cgatgttagc gaagtaagcg ccttttggcg
     4021 tcatcgccag taccgccaga atggagcctg gagacgccgg agagaccaga ccgccgttca
     4081 ggatggtcag ggtgaatacg ccggtcatac cgccgagaat caccgccaga atcaggcgtg
     4141 ggttcatcag cacgtacggg aagtaaattt cgtggatacc gcctaggaag tggataattg
     4201 ccgcgccgcc cgcagactgt ttagcgctgc cgcgaccgaa gaacatgtac gccagcagga
     4261 cgcccatccc cggacccggg ttagcttcaa tcaggaagaa gatggattta cccatctcat
     4321 gggactgctg gatacccagc ggtgagaaga tgccgtggtt aatcgcgtta ttgaggaaca
     4381 ggattttcgc cggttcaaca aaaatggacg ccagcggcag catatcgtgc gccaccatga
     4441 agttaacgcc cgccgccaga attttggaca ggacttcaac cgccggacca ataccgagga
     4501 acgccaggat ggcgaggatc ataccgatga tgccagcgga gaagttgttc accagcatct
     4561 caaaaccgga tttgatctta ccgtctaccc aactgtcgaa tttcttaatg cagtagccgc
     4621 ctaatggacc ggcgatcatc gagccgagga acatcggcat atccgcgccg acaataacgc
     4681 ccatggtagt aatagcgcct accacgccgc cgcgttcgcc gccaaccaga cgaccgccgg
     4741 tataaccgat gagcagcggc agcaggtagg tgatcatcgg accaaccagt ttcgccagcg
     4801 tttcgttagg caaccaccct gttggaataa ataatgcggt gataataccc cacgcgataa
     4861 acgcgccgat attaggcatc accatattgc tgaggaatcg accaaagctt tgcactttga
     4921 tcttaatatc ggatgacata aaaacacccc ttcttatgtt gctgtcgcgc aggctgaaag
     4981 cccgaggttt gttaatgtag cggcagaggt agccggaccc tgtagtgtag atactgcgca
     5041 atctggcact gaatcgttca actgtccaga caaggataat ttatgtgatt tgcgtcacat
     5101 aaatataggg gtagagaggt aatttatgtg atattgatca caaagttact gtgtaaaaaa
     5161 acaacgaatc tcatttttag cccttaaaag gctattttat gtgagatatt tcacactttt
     5221 attttggtgc tttgttgaat ttttgtgatc ctcttcacat gaaattttaa gcccgggtaa
     5281 cgtcaatacg atccgacaaa cattttgtcg cgagccctct cacgttatgt cattcagcaa
     5341 cttccttttg tgtctctttt cgtcttattt gagccatact atgattttta ctggttggca
     5401 aaaaggacac ggcatgaaac tcatcggtag ctacaccagc ccttttgtgc gcaaaatctc
     5461 tgttctgctg ctcgaaaagg gtattacctt cgaatttatt aatgaactac cttacgaggc
     5521 ggataacggc gtggcgcaat acaaccctct gggtaaggtg ccagcgctgg tgacggagaa
     5581 aggggagtac tggttcgatt cgccgatcat cgcggaatat attgaactgc tggatatcgc
     5641 gccagcgatg ctcccgcgtg acccgatggc agcgcttaaa gttcgccagc ttgaagcgtt
     5701 ggctgacggc attatggatg cagcgttggt gtctgtacgc gaacaggcgc gcccggcggc
     5761 gcaacaatcg gaaacggaac tgctgcgcca gcgggaaaaa atcaaccgca gcctggatat
     5821 gctcgaaagt tatctgagcg acgggacgct aaaaacggat acggtcaatc tggcgactat
     5881 cgcgattgcc tgtgcggtag gctatctcaa cttccgccgg gtcgcgcccg gctggtgtgt
     5941 tagccgcccc cacctggtca aactggtcga aacgcttttt caacgcgaaa gctttgcccg
     6001 caccgaagcg ccaaaggctt gacgcgcatt atgtccgcct gagcaaactc acgttacaat
     6061 cccccttatg tcgatatccc tctcccgcca ggagagggcc accaacagcc aggcattttc
     6121 atgacaagcg aaacgcgtac actctacagc cagcttcctg ctatcgatcg tttattgcac
     6181 gatagcgcct ttctttctct gcgcgatcgg tatggccata cccaggtggt tgatctgctt
     6241 aggcggatgc ttgacgacgc gcgcgacgtc atacggaata cgcaaacgct tcccgactgg
     6301 tacgcagact gggcgcaaga ggcgaaactc cggctggaaa atgcggcgca aagcgcgctg
     6361 cgcccggtga ttaacctgac ggggacggtg ctgcacacca atcttggccg cgcattgcag
     6421 gcgcaagaag cgattgaggc ggtaacgcag gcgatgcgcg cgccggtgac gctggaatac
     6481 gatttagatg gcgccgggcg ggggcatcgc gaccgggcgc tggcgacgct gttatgccgt
     6541 atcaccgggg cggaggacgc ctgtatcgtc aataacaatg cggcggcggt attgctgatg
     6601 ctggcggcga ccgccagcgg caaagaggtg gtggtttcgc gtggcgaact ggtcgaaatc
     6661 ggcggcgcgt ttcgtattcc ggatgttatg cgccaggcgg gctgtacgct gcatgaagtg
     6721 ggcaccacca accggacgca cgcgaaagat taccgtcagg cggtaaatga aaataccggg
     6781 ctgttgatga aggtgcatac cagtaattac agcattgagg gctttaccaa aacggtagag
     6841 gaagcggaac tggcggaaat cgggcgagag ctggatattc cggtggtggc ggatctgggc
     6901 agcggttcgc tggtggattt aagccaatat ggcttaccca aagagccgat gccgcaacag
     6961 ctcattgccg caggcgtcag cctggtaagc ttctccggcg ataagttgtt gggcgggccg
     7021 caggccggga tcatcgtcgg caaaaaagcg atgattgccc aactgcaaag ccatccgctg
     7081 aaacgcgctc tgcgcgcgga taaaatgacg ctggcggcgc tggaggcaac gttacgtctg
     7141 tatctgcacc cggaagcgtt ggcggagaaa ttacccaccc tgcgtctgtt aacccgcagt
     7201 gaagcgtcga ttcgcgaaca agcgcagcgg ttacaggcgc ggttggcggc acgttacggc
     7261 gatgaatttg cgctggaggt taaaccctgt ctgtcgcaaa tcggcagcgg ttcattaccg
     7321 gtagaccgcc tccccagcgc cgccatgacc tttaccccgc acgacgggcg cggtagtcgg
     7381 ctggaggcgc tggcggcccg ctggcgcacg ctgcctgtac cggtcattgg ccgaatttat
     7441 gatggccgtt tatggctgga tatgcgctgt cttgaagacg aaagccggtt tatggagatg
     7501 atgctgaaat gattattgca actgccggac acgtagacca cggtaaaacg acgttgctcc
     7561 aggcgattac cggcattaat gccgatcgcc tgccggaaga gaaaaaacgc gggatgacta
     7621 tcgatctggg ctacgcctat tggccgcagc cggatggtcg tgtgctgggc tttatcgatg
     7681 tgcctgggca tgaaaaattc ctctctaaca tgctggcggg cgtaggcggt atcgatcacg
     7741 ctttgctggt ggtcgcctgt gatgacggcg ttatggcgca aacgcgcgag catttacaga
     7801 tcctacagct gacgggcaat ctccagctca ccgtcgcgct gaccaaagcc gatcgcgtgg
     7861 acgaggcgcg tatcagcgaa gtacgtgaag aggtgctggc ggcgctcgac aactatggct
     7921 tcgccgatac cgttttattt gtcaccgccg ccaatgaagg acgcggtatt gcagaacttc
     7981 gcgctcattt acagcagctt cctgcacgtt tacacgccgc gcagcatcgc ttccgtctgg
     8041 ctatcgaccg tgcgtttacg gtgaaagggg cgggactggt ggtgaccgga acggcgttga
     8101 gcggagaggt aaacgtgggc gatacgctat ggttgaccgg cgttaatacg ccgatgcgcg
     8161 tacgaagtct acacgcgcaa aatcagccta ccgaccatgc gtatgccggg caacgtattg
     8221 cgctcaatat tgcgggcgat gcggagaagg agcagcttaa ccgcggcgac tggctgcttt
     8281 ccgatgcgcc ggcgggggag gctttttccc gggtgatcgt ttctctggcg cttcatgcgc
     8341 cgctttccca atggcaaccg ctacatattc accatgccgc cagccatgtg accggtcgcg
     8401 tctctttgct ggaaggcgcg ctggccgagc tgatctttga tacgccgttg tggctggccg
     8461 ataatgacag actggtattg cgtgatattt ccgcacgcgc cacccttgcc ggcgcacgcg
     8521 tggtgacgct taacgcgccg cgccgcggta aacgtaagcc agattatttg cactggcttt
     8581 caacgcttgc cgatgcgcag gacgatagcg cagcgttggc cattcatctg gaacgcgggg
     8641 ccgtcaacct gccggatttc ggttgggcgc gtcagcttaa tcctctcggt atgcgtcagc
     8701 ttattgagca acatggtttt atccaggccg gagacaatct gttaagcgcg cccgtcgccg
     8761 cccgctggca gcgtaagatt cttgatacgc tggcgaccta ccacgaacag caccgcgatg
     8821 aaccggggcc gggacgcgag cgtttacgcc gcatggccct gccaatggag gatgaagcgc
     8881 tggttctgat gctgatcgag cggatgcgcg acgagggcct gattcatagc catcacggtt
     8941 ggttgcatct gccggatcat aaagcgggat ttagcgatga gcagcaggcc gtctggcaaa
     9001 aagtcgaacc gctatttggc gatgagccct ggtgggtacg cgatctggcg aaagagaccg
     9061 gaacggaaga acaattgatg cggctggtgc tgcggcaggc ggcacagcaa ggcatcatta
     9121 ccgcgatcgt aaaagatcgg tactatcgta acgatcggat tgtcgctttc gccaatatga
     9181 tccgcgagct ggatcaagag agaggatcaa cctgtgcggc ggattttcgc gacaggctga
     9241 atgtagggcg gaaactggcc attcagattc ttgaatattt tgaccggatt ggatttacac
     9301 gacgtcgtgg gaatgatcat ttattacgtg atgcgttatt atttccgcaa aaagaatgaa
     9361 atggttaaat taaataacaa atgaagcaat acaattattg cgttgcttta taaaaagcac
     9421 atcagcaaat gaacctgatg tgctttttat ttttctggct tcttaaaata gccatcgtga
     9481 gcctattatc agaatagttt tgcccatatt ctttgcgcct tattcaggcg actcacgacg
     9541 agattgtgga actttatcgc gcggcgatgt aacgcctttg cccggtggcg cggacgctta
     9601 ccgggcctgc gtagacgatg caggccggat agggcgtaac acgttatctt cggtcgagct
     9661 tttgctgcgc cagccagacg gcgcccagcc tgcctgcctg atttcccagt tggcagggct
     9721 gaatcggcac ctggagcgcc tcccacattt caaacgtttc aagatgccgc gtcaggagcg
     9781 ggtagagctt ttcctgttcg cttattcctc cgccgatcag caccacgccc ggatcaaaca
     9841 tagagatcac gctgtaaacg ccgcgtgaca gataacgcgc ccagtcattg accgcctcac
     9901 gcagatgaac atcggtcgcc attcgttcga agatcacatc cgcaggcggc atctcttctg
     9961 caggcagcgc cagagcctgg cggcacgacg ccattaatcc gctggttgac gcgattttat
    10021 gcatactttc gccattattc ccgaccggca tgacgccgaa ttcaccggcg tggaaatgtg
    10081 cgccgcgata cagttctcgt ccgacgataa taccgccgcc aatgccggtt ccaatggtga
    10141 tacagaccag attgtcataa tgctgcccgg cgcctcgcca catttcgccc agcgccgcgc
    10201 agttcgcgtc gttctccacg accagcggca gatcggttag cccgctgaac aactccatca
    10261 ggttgacgtc atccaggtat gccagcgcgc ccgcttttgc cgcatgaccg ttatggggat
    10321 taatatggcc ggggaaactg accccgattg ccgcaatgtc atagtcctgc tggcaacgcg
    10381 ccaccacatc ctgccatttg cgggtaaacg tggaggcgtc ctctggcgta tcgaattgat
    10441 gatgggttaa ttcttcgccg tcactgttaa tcacgccata tttgacgtga gttcctccca
    10501 catcaatacc gatatattgc tgcatagtgt tctccgtacg ttaaacaggc acctgtttag
    10561 tatggctaaa accagacgga gaaacgtaaa ggaaagtaat tcgtgattgc tgtcgtaaag
    10621 cgagaaacca ttggcgaaaa attcaccagt accgtctacc cttgtggagt acctttacaa
    10681 taaggagttg gtcatgacga acaatccccc ttcaacacgt attcagccaa gtgaatacgg
    10741 gtacccactg aagttaaaag cccgctatga caattttatt ggcggtgact gggttgcgcc
    10801 cgccgacggc gaatattatc aaaacctgac gccagtgacc ggccagccgc tatgtgaagt
    10861 cgcttcctcc ggtaaaaaag atatcgattt agcgctcgac gccgcgcata aggcgaaaga
    10921 taagtgggcg catacgtcag tacaagaccg tgccgctatc ttgtttaaga tcgccgatcg
    10981 gatggaacaa aacctcgaac tgttggcgac agcggaaact tgggataacg gtaaaccgat
    11041 tcgtgaaacc agtgccgccg acataccgct ggcgatcgat catttccgct atttcgcctc
    11101 ctgtatacgt gcgcaggagg gcgggatcag cgaagttgat agcgaaaccg tggcctacca
    11161 ttttcacgaa ccgcttggtg tcgtggggca gataatcccg tggaactttc cgctgctgat
    11221 ggcaagctgg aaaatggcgc cagcgctggc ggcaggtaac tgcgtggtgc ttaaaccggc
    11281 acgcctgacg ccgctttccg ttttactgtt aatggaagtc attggcgatc tgttaccgcc
    11341 gggcgttgtc aacgtcgtga acggcgcggg cggcgagatt ggcgaatatc tggcgacctc
    11401 aaaacgtatc gcgaaggtgg cgtttaccgg ttcgacggaa gtgggtcaac agatcatgca
    11461 gtacgccacg cagaacatta ttccggtgac gctggagtta ggcggcaagt cgcccaatat
    11521 cttcttcgcc gacgtgatgg atgaggaaga tgcgttcttt gataaagcgc tggagggatt
    11581 tgccctgttt gcctttaacc agggcgaggt gtgtacctgt ccaagccgtg cgctggttca
    11641 ggagtccatc tatgagcgct ttatggagcg cgctattcgc cgggtggaga gcattcgcag
    11701 cgggaacccg ctagatagcg gtacacagat gggagcgcag gtctctcacg gccagcttga
    11761 gactatcctc aattatatcg atatcggtaa aaaagagggg gccgatattc tgaccggtgg
    11821 gcgacgcaag gaactggatg gcgaacttaa agagggctat taccttgagc ctaccattct
    11881 gtttggtaag aataatatgc gcgtctttca ggaggagatc tttggcccgg tgctggcggt
    11941 aaccaccttt aaaaccatgg agaaggcgct ggaaatcgct aacgatacgc aatatggcct
    12001 gggtgctggc gtctggagcc gcaacggcaa tctggcctat aagatggggc gcggcattca
    12061 ggccgggcgc gtatggacca actgctatca cgcctatccg gcacatgcgg cgtttggcgg
    12121 ctataagcag tcgggcatcg ggcgcgaaac ccataagatg atgctggaac actaccagca
    12181 aaccaagtgc ctgttggtga gttattccga taagccgctg gggctgttct gacgcaagag
    12241 gtaatgcccg atggcgctgc gtttatcagg cctacaagaa tttatcgcaa tatactgata
    12301 ttgcaaatct tgtaggccgg ataaggcgca gccgccatcc ggcacagtat taccgctcgt
    12361 taatccaaat ccgcatttcg ccctcgccac ggttggccca gctaaaccac ggaatgaatg
    12421 ttagcgtctg cggctgacgc gatgacggcg cgttatcgta gtgccacaac gcctgatgct
    12481 gcgcatccgc ggcgctttgc ttctcgcctt cggcctgaat cagcatctta tgcgcaaaaa
    12541 gccctttgcc ctcaaagacc cggaactcac tctctttcgg tagccacaga ttatgcagtt
    12601 cttcgccgtt atcggcctgc tcaaggcaat agaccagcgg cccgcgctga atagcgacct
    12661 taccggcgac gtgacgcgcc agcggattgc catacacgcg gcgaaccggc atcggcagcg
    12721 tcaggcttat cgtatcgccc tcctgccagg ttcgacggat atgcagataa cctttgcgaa
    12781 tatcctgctc cacttccagc ccgttgagcg tcacttttgc ctcagggcac cagtccggca
    12841 gacgtagcgc cagcgtgtga cgtaccggct gcacagaatc gatggcgatc ttcacctgct
    12901 catgccacgg gtagttcccg ctgattcgca gtttgagcgc gccattttca accggtattt
    12961 ccatgctgtt acccacgtac atattgatgt acagcgcatc cgcacgcggc gtgtagatgt
    13021 agtgaccaat ggacgtgagt acgcgggcga tattcggtgg gcagcaggcg cagccaaacc
    13081 agcgctggcg gatgggttta acgtgatcgt agatatggtt gaattttaac gattttggat
    13141 gcacttccag cgggttgacg tagaagaaat gcttgccgtc gagcgccata ccgccgagga
    13201 cggtgttgta cagcgcgcgc tccatcacgt cggcgtactg gctatcggct tccatttcca
    13261 gcatccggcg ggcgaacatc atcaggccga ttgaagcgca gctttccgca tagaccgaat
    13321 cattcggtaa atcgtaatcg ctgctaaagg cttcgccgct gctttgtgaa ccgatgcctc
    13381 cggtgatata cagctgacgc tgcgccatat ttttccacag gcgcaggcag tcctggcgtt
    13441 tgccttcatc gttgctcagg cgagcgagat gcgccacgcc agtcatcaga tagacaaaac
    13501 gtaccgcgtg gccgattgcc gtctgctgct gcgaaattgg cagatgcgcc tggctgtagg
    13561 ctttgtcttt gaccatccac gccgggccgt aggtatgcca gtaagaggtt tggccgcgtt
    13621 tttcgtactc ttcgtcgtag aagtgcggtt gggcgccgcg ctgcccgata aagtaacttg
    13681 ccagcgtcat atagcgcggc tgctctgtta cctcatacag acgcatcagc gccagctcaa
    13741 tttccgggtg gcccggataa ccgtgcagct gattttcgcc agggccgaaa gtgctgtcga
    13801 tatgatcggc cagacgacaa acgacgtcta gcagccgacg cttgccggtg gcctgaaaga
    13861 aggcgacgcc cgcttcaatc agatgcccgg cgcaataaag ctcatggcac tccgccaggt
    13921 tgctccagcg ttcttgcggg gcttttgccg taaagtacgt attgagatag ccatcgtcac
    13981 actgcgcggc ggccaccagt tcaatcacct catcggcggt tttctcaagc tctgggtcgg
    14041 gtttttggca cagtgaccag gcaaccgctt ccagccattt cgccacgtcg ctgtcctgaa
    14101 agaccatgcc gtaaaagtcg cccgtctgct ggcctgcggc aatgcggaaa ttttcaatgg
    14161 catggctggg ttcagcctct ggaatacgat cgtttaacgc atcccactgg taaggaataa
    14221 ccacatcgcg aaccagttgt tgatactgtc cgagtaacgg atcgctgacc gtcagtttat
    14281 gcagatcgac ttccagtacg ttcatttcgt gctccttaag gctgtagagg tcatagatat
    14341 tcctcgctga cggggtattt tatggcagta atttttattt tcgcgttatg acctgattca
    14401 ttttgcccag atagcggtga gcgacaaggc gataaaagag taaaaaaaga tgacgattcc
    14461 gactcgtatt taaaaatgtg agatggatcg agtgaaatga ct
//
LOCUS       DAJVKX010000117        14496 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.117, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000117 DAJVKX010000000
VERSION     DAJVKX010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14496
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.117"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            111..695
                     /locus_tag="OPY25_003481"
     CDS             111..695
                     /locus_tag="OPY25_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0928998.1"
                     /translation="MKKAILAAAMVMAMGSTSAMAVEGGQIEFHGLVSATTCSKVVSS
                     SRGNQATDGDVYLTTAAPGDITEGVAANAYGALPAPFSIILDCSGAADVTDATKASLV
                     MDSSFSNTTGTLDNDTTLSVAGETGAENVNIAIHDADTKTQVKIDGAEIHEASFKNKV
                     ATYNFMASYVRADASKEVTTGHVTTNAMYTFTYQ"
     gene            874..1608
                     /locus_tag="OPY25_003482"
     CDS             874..1608
                     /locus_tag="OPY25_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000967611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HCS0928999.1"
                     /translation="MLYVKKSLTAIVLASAVFSTFSYADIIISGTRIVYDENKKDVSI
                     RLENKGTRPLLVQNWIDLGNDNDDPGSIKAPFVSTPPVSRVEPKRGQSVKIMYTQASA
                     LPKDRESVFWFNVLEVPPKADTSKEENKSLLQLAFRTRIKLFYRPTGLKGQPAEAAKQ
                     LKWQIASEQGYAVLRADNSTPYFVSFNDATYTAGGKRYDVEATMVAPFSKSSFTVKGL
                     SGASAGKLEYHAINDFGGLIEGSVSL"
     gene            1668..4274
                     /locus_tag="OPY25_003483"
     CDS             1668..4274
                     /locus_tag="OPY25_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane usher protein"
                     /protein_id="HCS0929000.1"
                     /translation="MPKKTMLAVCCALFYSQSSISAESVEYDSSFLMGSSASTIDISK
                     YSDGNPTPVGTYSVKVFVNENPVSSLSIPFIDIGKVSAEACLTQKNLAQLHIKQPEIN
                     ATNQILKKGEEEDQDCLNLPVAIAHSEVNFDMGEQRLDITVPQAWLIEGYDGYVEPSL
                     WEDGIPAALLSYSANGYHSTNGSADNDSMYAAFNTGINLGAWRFRANGNYNWTKDSGS
                     SFDYQNRYLQRDLPSMRSQLVVGETYTTGETFDSVSIRGARLYSDNRMLPSQLANYAP
                     IIRGVANSNAKVSITQGGYKIYESTVPPGPFEISDISPSGYGSDLIVTVEEADGSKRT
                     FSQPFSSVMQMQRPGVGRWDFSAGEVNDDELHDKPYMAQGSYYYGLNNFLTLYTGVQG
                     TDNNYLAGLLGVGLNTPLGAFALDVTQSRTEIPEDKTYKGQSYRLTWNKLIEPTATSF
                     NVAAYRYSTQDYLGLNDALQLIDDAKHKDADDRNTMLNYSRMKNQVTVSINQPLRFKE
                     VDYGSFFLSGSWTDYWATNESRTDYSLGYGRGFSWGSLSINLQRSWDEDGEKDDSLYI
                     NFNVPLENLLGGGRRKSGFSSLTAQMRTDFDGGYQLSMNSNGSSEDHTLNYSVNTGYT
                     MQKNEKNITDVSGYASYQSPWGDVTASASANNDSSRQYSLATTGDFVLHGGGVTFTND
                     NFGNSDAIVLVKAPGAKGARINGGNSTIDRWGYGATNSLSAYRENQVNIDIDTLENDV
                     ELKSTSTTLIPRDGAVVLASFETDQGRSVILNMSRNDGKALPFGAEVYENDVQIDNMG
                     QGGQAFVRGISDAGELSVRWFEENQPATCLATFALPATQQTVGSSQTLLLDHITCRVN
                     NLKSNGIDNEKE"
     gene            4261..4827
                     /locus_tag="OPY25_003484"
     CDS             4261..4827
                     /locus_tag="OPY25_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000827925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0929001.1"
                     /translation="MKRNKYLLAASVLAVIFPLTSQAENINVDFTATVLATTCSMSIA
                     ALDGSNLSGDATSGYTLNVGDVGLDKIIKKSAESQKNFKFVAKDCSVALTKITTTLAS
                     STDASGNFIKNQSAASGAATNVGMGFKRKSTTDETYFTPGSGSFSWTSDERAANEVEM
                     TVALRELTDGAGTTGAFSSTATFNFTYQ"
     gene            4842..5450
                     /gene="staE"
                     /locus_tag="OPY25_003485"
     CDS             4842..5450
                     /gene="staE"
                     /locus_tag="OPY25_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein StaE"
                     /protein_id="HCS0929002.1"
                     /translation="MKKQILRVVIFSSLIATGAGISTMTYADGTNSLDLTVNANITAG
                     TCSASVVEGDTITDTIAFGNVYISEVYAKSKIKLFKLRFSDCVGLKDKKAKFRLAPNN
                     VACPGSSGTDGQFANASTSTTKAAMVAMEVWTTETPGGTGAVKLHCWSKPEQTVDLSG
                     ASVTTPVDFPLSAMMVAQSGGTLQNMTAGDFYSPTTFTITYQ"
     gene            5462..6046
                     /locus_tag="OPY25_003486"
     CDS             5462..6046
                     /locus_tag="OPY25_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001253684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0929003.1"
                     /translation="MRRLREPTLATLFSGLATALFSATLYADTNVNFTASVQKDTCQI
                     KIDGNGTVNFATIAPAYFADGITAETDYEGGKEFTIKLISCPISDGKITNVTFNFAPL
                     NGQFSPENQQVFPNDIATDAGGVDNVGVVIFTTDSPRTNVLNTDGSSRATFAASTYSD
                     TVWTFYSRMQKIRSAEKVTTGELSSRVLVNVSYE"
     gene            6083..7258
                     /locus_tag="OPY25_003487"
     CDS             6083..7258
                     /locus_tag="OPY25_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin"
                     /protein_id="HCS0929004.1"
                     /translation="MLLKNTTWFAAFFLMMAIMSNCYAINTTLAVGDYASSEHDGPSG
                     DSVFTDNSHNFGQTIAIHKETALRQITVFNWSGIQYVMEMFCNGSGNHTYLQLTHNYI
                     SAGKSYNGHPLYKTSIPGFYFTIEMTFLQPAENMTSSTFWFDKTSTPITSEFTEFPSA
                     CSRTNVYSNLGKLMYGLKIYAYVDSDFAPTEAQLQSFTLSKNGDSDFYIDNPGSGLSN
                     YKMKFNLAATGLKAVWPTCSASTISGTNVSGSTVKLGSFYPKQIMEGLSPTKFQINLS
                     SCQYINNIEVKLASNNVGTKNTSLLTNNSTSNTKASGIGVLIEGLKSSSSAQMVLKPN
                     DSSSIYKDTTNNTGDGSPVGSATKSLYFQATLKPDGDNPTINPGDFKATAQFSITYP"
     gene            7368..8162
                     /gene="panB"
                     /locus_tag="OPY25_003488"
     CDS             7368..8162
                     /gene="panB"
                     /locus_tag="OPY25_003488"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HCS0929005.1"
                     /translation="MSKPTTIAVLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLV
                     GDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQAFENAA
                     IVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAG
                     QILLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAEAGDMRAAVRQYMAEVESGVYPGEEHSFH"
     gene            8288..9142
                     /gene="panC"
                     /locus_tag="OPY25_003489"
     CDS             8288..9142
                     /gene="panC"
                     /locus_tag="OPY25_003489"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HCS0929006.1"
                     /translation="MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPQG
                     LEGQTYVDVPGLSTMLEGTSRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIR
                     KMVADMGYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAG
                     NRELQEIIAIAEQELNEKGFRADDIQIRDADTLLELTETSKRAVILAAAWLGQARLID
                     NQSVTLAQ"
     gene            9237..9617
                     /gene="panD"
                     /locus_tag="OPY25_003490"
     CDS             9237..9617
                     /gene="panD"
                     /locus_tag="OPY25_003490"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HCS0929007.1"
                     /translation="MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWR
                     PKVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(9624..10853)
                     /locus_tag="OPY25_003491"
     CDS             complement(9624..10853)
                     /locus_tag="OPY25_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCS0929008.1"
                     /translation="MVMRVVLILLFFFAGNVLAALPARYMQTTKDAAIWSQIGDKMVT
                     VGNIRAGQILSVTPVAVDYYAFKFGFGVGFIDKGHLGPVQGKQKVEDGLGDLNKPLSN
                     QNLVTWKDTPVYNAPDISSAPFGVLVDNLRYPIISKLKGRLHQTWNQIRIGDRLAYVN
                     AMDAQEDNGIPILTYHHILRDEENTRFRHTSTTTSVRAFSNQMTWLRDRGYATLTMYQ
                     LEDYIYNRANFPARAVAITFDDGLKSVSRYAYPVLKQYDMKATAFIISSRIKRHPQKW
                     NPRSLQFMSVSELRKISDVFDFQSHTHFLHRVDGHRRPILYSRSYHNILFDFERSRRA
                     LTQFTPHVFYLSYPFGGYNATAIKAAKDAGFHLAVTTVRGKVKPGDNPMLLKRLYILR
                     TDSLETMSRLIVNQPQG"
     gene            complement(10915..11355)
                     /locus_tag="OPY25_003492"
     CDS             complement(10915..11355)
                     /locus_tag="OPY25_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCS0929009.1"
                     /translation="MLGWVITCHDDRAQDMLDRLERKNGPLAQCRAVNFWRGLSSNML
                     SRMMCDALHATDSGEGVIFLTDISGAAPYRVASLMSHKHPQCEVISGISYSLIEEMIP
                     LRESMSSSAFRDQIVALGAPDVTSLWHQQQKNPPFVLLHDLYEF"
     gene            complement(11460..12230)
                     /locus_tag="OPY25_003493"
     CDS             complement(11460..12230)
                     /locus_tag="OPY25_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0929010.1"
                     /translation="MMQLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGEMHGFSYMQFIVPGLIMMAVITNSYANVASSFFSAKFQRNIEELLVAPVPT
                     HVIIAGFVGGGVARGLCVGILVTAISLFFVPFQVHSWVFVALTLILTAILFSLAGLLN
                     AVFAKTFDDISLIPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGIHDVPLVTTFGVLVIFIATFYLLCWSLIQRGRGLRS"
     gene            complement(12227..13153)
                     /locus_tag="OPY25_003494"
     CDS             complement(12227..13153)
                     /locus_tag="OPY25_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0929011.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVNVFGYDLEKDVVNAKRQLGLVSQEFNFNPFETVQQIVVNQ
                     AGYYGVEHKEAVLRSEKYLKQLDLWEKRHERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNAKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKNLLSKLKSETFILDLAPKSPLPKLTGYQYRLVDTSTLEVEVLREQGVNSVFSQLS
                     EQGVQVLSMRNKANRLEELFVSLVHEKQGDRA"
     gene            13262..13924
                     /gene="can"
                     /locus_tag="OPY25_003495"
     CDS             13262..13924
                     /gene="can"
                     /locus_tag="OPY25_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HCS0929012.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDALEVEHIIICGHSGCG
                     GIKAAVENPELGLINNWLLHIRDIWLKHSSLLGKMPEEQRLDALYELNVMEQVYNLGH
                     STIMQSAWKRGQNVTIHGWAYSINDGLLRDLDVTATNRETLENGYHKGISALSLKYIP
                     HQ"
     gene            complement(13982..>14496)
                     /gene="hpt"
                     /locus_tag="OPY25_003496"
     CDS             complement(13982..>14496)
                     /gene="hpt"
                     /locus_tag="OPY25_003496"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCS0929013.1"
                     /translation="IPEAEIKARIAELGRQITERYKDSDSEMVLVGLLRGSFMFMADL
                     CREVQVPHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSK
                     VREILGLREPKSLAICTLLDKPSRREVDVPVEFVGFSIPDEFVVGYGIDYAQRYRHLP
                     YVGKVVLLDE"
BASE COUNT         3880 a         3778 c         3499 g         3339 t
ORIGIN      
        1 taaatattat acaaaaatta tcctcaaacg ctaaaatcca agccctgcta tttaatataa
       61 attaatagat atttaattta ttaacatttc aatcctgtaa ggatacagca atgaaaaaag
      121 cgattttagc tgccgcaatg gttatggcta tgggttctac ttccgcaatg gcagttgaag
      181 gcggccagat cgaattccac ggtttagtga gcgcaacaac ctgttctaaa gtagtttcct
      241 cttcacgcgg taatcaagcg actgatggtg acgtatatct gactacagca gccccaggcg
      301 atatcactga aggcgttgct gctaacgcat acggcgcgct tccggctccg ttctctatca
      361 tcctggattg ctcaggcgcg gctgatgtaa ctgatgccac taaggcttct ctggtaatgg
      421 attcgtcatt ctctaacact accggcactc ttgacaatga caccacactg tccgtggctg
      481 gtgaaactgg ggctgaaaac gtgaatatcg ccatccatga tgccgatacc aaaactcagg
      541 ttaaaatcga tggcgctgaa attcatgaag cgtccttcaa aaacaaagtt gcaacctata
      601 actttatggc gtcttacgtt cgtgccgatg cttctaaaga agtgactacc ggtcatgtaa
      661 ccacgaacgc aatgtatacc tttacttacc agtaacagga catacggtta tcactaataa
      721 gtactcgtac ctttccttga gttagcgtgc ttatcagtta ttgatctcat ataaccttcg
      781 gggtccagga attatttcaa cgattccggg ggttcattca atttaattaa attcaaagtt
      841 gatttcatta tcttctacag gcaaggaacg cttatgttgt atgtaaaaaa aagcctgacc
      901 gccatcgtat tagccagtgc tgtatttagt acctttagct atgcggatat tattatctcg
      961 ggcaccagaa tcgtttatga cgaaaataaa aaagacgtca gtatacgact ggaaaataag
     1021 ggtacccgcc cattattagt ccaaaactgg atagacctgg gtaacgataa cgacgatccc
     1081 gggagtatta aagcgccttt cgtttctacc cccccggttt cacgcgttga gcctaaacgt
     1141 gggcaatcgg taaaaattat gtatacccag gccagcgcgc tgccgaaaga ccgggaaagc
     1201 gtcttctggt ttaacgtact ggaagtaccg ccaaaagcgg ataccagcaa agaagagaat
     1261 aaaagcttac tgcaactggc ttttcgtacc cgtatcaaac tgttctatcg cccaacagga
     1321 ctaaaaggcc agcctgctga agcggcaaaa caactgaagt ggcaaatagc gagcgaacaa
     1381 ggctacgcgg tactacgtgc tgataactca actccgtatt tcgtctcatt taatgacgct
     1441 acctacactg caggcggtaa acgttatgac gttgaagcca ccatggttgc gcctttcagt
     1501 aaatcatcct tcaccgtgaa aggcttgtca ggcgctagcg ccggaaaact ggagtatcac
     1561 gccattaatg attttggcgg tttgattgaa ggttccgtat cgctgtaacg gattaaccaa
     1621 gaatcaggat gaagaaatcg gtgtaaaact ttccacattc caaggccatg ccgaagaaaa
     1681 cgatgctcgc agtttgctgt gcgctatttt atagccagag cagtatttcc gctgaaagcg
     1741 ttgaatacga cagttccttt ttaatgggga gtagcgcctc cacaatcgat atcagcaaat
     1801 actccgacgg caacccaacg cctgtcggaa cgtatagcgt gaaagttttt gtcaacgaaa
     1861 accccgtatc aagcctgtcc atacccttta tcgatatcgg caaggtcagt gcagaagcct
     1921 gcctgacaca aaaaaatctg gcgcagttgc atatcaaaca gccagaaatc aatgcgacca
     1981 atcaaattct gaaaaaaggg gaggaagaag atcaagattg tctgaacctt cccgtcgcca
     2041 tcgcgcattc agaggtcaat tttgatatgg gcgaacagcg tctggatatt accgtacctc
     2101 aggcgtggct cattgaaggt tatgacggct atgttgagcc ttcgctgtgg gaagatggta
     2161 ttccggcagc gcttctgtcc tactcggcta acggctatca cagcaccaat ggcagcgccg
     2221 ataatgacag tatgtatgcg gcgtttaaca ccggtattaa cctcggcgca tggcgttttc
     2281 gcgccaacgg caactataac tggacgaaag actcaggaag ctcctttgac tatcagaatc
     2341 gctacttgca gcgcgatctg ccttcaatgc gctctcaact tgttgtcggt gaaacctata
     2401 ccacgggcga aacatttgac tccgtaagca ttcgcggggc tcgtctgtat agcgacaacc
     2461 gaatgctacc ttcgcagctt gccaactatg cgccgattat tcgcggcgta gcaaacagta
     2521 acgccaaggt cagcataacc cagggcggct acaaaattta tgagtccacg gtaccgccag
     2581 gcccctttga aatcagcgac atcagtcctt ccggctacgg tagcgacctc atcgtcaccg
     2641 ttgaggaggc cgacggcagt aaacgcacct ttagccagcc attctcctcg gttatgcaga
     2701 tgcagcgccc gggcgtcgga cgttgggatt tcagcgccgg tgaagtgaat gacgatgagc
     2761 ttcatgacaa gccctatatg gcgcaaggtt catattacta cggccttaat aactttttga
     2821 ccctctatac aggtgttcag ggaacagata ataactatct tgccgggttg ctgggtgtcg
     2881 gcctcaacac ccctcttggc gcatttgcac ttgatgtcac tcagtctcgt acagagatcc
     2941 ctgaggataa aacctataag ggccagagct accgactgac gtggaacaag ctgattgaac
     3001 cgacggcaac ctcctttaac gtagcggcat atcgttattc aacgcaggac tacctgggcc
     3061 tgaatgatgc gctacagctg attgatgacg cgaaacataa agacgcggac gatcgcaaca
     3121 ccatgcttaa ctattcgcgc atgaaaaacc aggtcacggt cagcataaac caaccgttga
     3181 ggtttaagga agtcgactac ggttcctttt tcctctcagg ctcctggacc gactactggg
     3241 ctaccaatga aagccgtacc gactatagcc tcggttacgg aagaggtttt tcgtggggca
     3301 gcctcagtat caacctccag agatcctggg atgaagatgg cgaaaaagat gattcgctct
     3361 atatcaactt caacgttccg ctggagaatc tgctgggcgg cggtcgccgt aagtcgggtt
     3421 tcagctcact gacggcgcaa atgcgcactg attttgacgg cgggtaccag ttgagcatga
     3481 acagcaacgg cagcagtgaa gaccacacgc tgaactacag cgttaacacc ggctacacca
     3541 tgcagaaaaa tgaaaagaac atcaccgatg tcagcggcta cgccagctat cagtccccct
     3601 ggggagatgt tactgcttca gcctctgcca ataatgacag cagccgacaa tattcgctcg
     3661 ccacaaccgg agactttgtc ctgcatggcg gtggagtgac gttcactaac gataacttcg
     3721 gtaatagcga tgccatcgtg ctggtaaaag cccctggcgc gaaaggcgcg cgcatcaatg
     3781 gcggcaacag caccatcgat cgctggggct acggcgcgac gaactcgctt tccgcctaca
     3841 gagaaaacca ggtcaatatt gatatcgaca cgctggaaaa cgatgtcgaa ctaaagagca
     3901 ccagtacaac cctgataccg cgtgatggcg cggtagtctt agccagtttc gaaactgacc
     3961 agggacgctc ggtcattctc aacatgtccc gtaatgacgg aaaagcccta ccatttggcg
     4021 cagaagtcta cgagaacgat gtgcagatcg acaacatggg ccagggcggt caggcttttg
     4081 ttcgcggcat cagcgatgca ggcgaactct cagtacgctg gtttgaagaa aaccagccag
     4141 caacttgttt agcaaccttt gcgttgccgg caacgcaaca aacggtaggg tccagccaga
     4201 ccttactgtt agaccacata acctgtcgtg ttaataacct taaatcaaat ggaatagaca
     4261 atgaaaagga ataaatacct tttagcagcc tctgtgctcg ccgtgatatt tccgcttacc
     4321 agtcaggcgg aaaatatcaa cgtcgacttt accgccaccg tgttagccac gacctgcagc
     4381 atgtcaattg cggcgttaga tggctcgaac ttatcgggtg atgccaccag cggctatacg
     4441 ctgaacgtcg gcgatgtcgg gttggataaa attataaaaa aatcagcgga atcgcagaaa
     4501 aactttaagt ttgtcgcgaa ggattgcagt gtcgctctga ccaaaatcac caccacgctt
     4561 gccagctcca cagatgccag cggcaatttt atcaaaaacc aatcagcggc aagcggcgct
     4621 gccaccaatg ttggcatggg ctttaagcgc aaaagcacta ccgatgaaac ctatttcacg
     4681 cccggctcag gctcatttag ctggacttcc gacgagcgcg cagcaaacga agtggaaatg
     4741 acggtcgcgc tgcgtgaact gaccgacggc gcgggtacca caggtgcttt cagctcaacc
     4801 gctacgttta acttcactta tcaataacaa ggacgatgat aatgaaaaag caaatattgc
     4861 gcgtcgtgat ttttagctcg ctgattgcca cgggagctgg catatcaacg atgacatatg
     4921 ccgatggaac caacagtctg gacctgaccg tgaacgccaa tatcactgcg ggtacgtgtt
     4981 ctgcatccgt ggttgaaggt gataccatta ccgatactat cgcttttggc aacgtttaca
     5041 tttctgaagt atatgcaaaa agtaaaataa aacttttcaa gttacggttc agtgattgtg
     5101 tcggtctcaa agataaaaaa gctaagttca gactagcccc aaataatgta gcatgcccgg
     5161 ggagcagcgg cactgatggg caattcgcaa atgcctcgac ttcaacaaca aaggcagcaa
     5221 tggtcgccat ggaagtatgg acgacagaaa cccctggagg cactggcgcg gtaaaacttc
     5281 actgctggtc gaaaccagaa caaaccgtgg atttatctgg tgcaagtgta acaacgcctg
     5341 ttgattttcc tttaagcgct atgatggtcg ctcaaagcgg cggtacgctt caaaatatga
     5401 cagcgggaga tttctactcg cccaccacct tcaccatcac ttaccagtaa tggtgatacc
     5461 aatgagacgt ttgcgcgaac ccacgctcgc cacgttattt tcagggctgg caacagccct
     5521 gtttagcgcg acgctgtacg ccgataccaa tgtgaatttc accgccagcg tgcagaagga
     5581 cacctgccag ataaagatag atggcaatgg aacggtaaac ttcgccacca tagcgcccgc
     5641 ctattttgcc gatggcatta ccgcggaaac cgattatgag ggggggaaag agttcaccat
     5701 taagcttatt tcttgcccga tcagtgatgg taaaataacc aatgtcacct ttaatttcgc
     5761 accactaaac gggcagttct cacctgagaa tcaacaagtt tttcctaatg acatcgctac
     5821 cgatgctggt ggcgtagaca atgtcggcgt ggtgattttc accaccgatt caccacgcac
     5881 caacgtgctt aatacggatg gttcatcgcg ggcgactttt gctgccagca cctacagcga
     5941 caccgtctgg accttttact ccagaatgca aaaaatacgc agtgccgaaa aagtgacgac
     6001 cggtgaactt agcagccgtg tactggtgaa tgtctcctat gaataatcag gagattttat
     6061 taaacgaaag gatatcgtta atatgctttt aaaaaacaca acatggtttg ccgccttttt
     6121 cctgatgatg gctatcatgt ccaactgtta tgccataaat actaccctgg ccgttggcga
     6181 ctacgcctcc agtgaacatg atggcccaag cggggattcg gtattcactg ataacagcca
     6241 caattttggg cagaccatcg cgattcataa ggaaacggcg ctgcgccaga ttaccgtttt
     6301 taactggtcc ggcatccagt acgttatgga gatgttctgt aacggcagcg gcaaccacac
     6361 ctaccttcaa ctgacccata attatatctc tgctggcaaa agctataatg gacatccgct
     6421 gtataaaacc tcaattcccg gtttttattt caccattgag atgaccttcc ttcagccagc
     6481 agagaatatg acctcaagca ccttctggtt tgataagacc tcaacgccga tcaccagcga
     6541 gttcacggaa tttccgtcag cctgctccag aacaaatgtt tatagcaacc ttggcaaatt
     6601 aatgtatggc ctgaaaatct atgcctatgt cgactctgac ttcgcgccga cggaagccca
     6661 gcttcaaagc tttacgctgt ctaaaaacgg cgactccgat ttctacattg ataacccggg
     6721 cagcggatta tcaaactata aaatgaagtt taacctcgcc gccacaggac ttaaggccgt
     6781 ctggccaacc tgctcggcca gcaccattag cggcaccaat gtttcgggat caacggttaa
     6841 gctgggtagc ttttatccaa agcagattat ggaagggctg tcgccgacca agttccagat
     6901 caatctctcc tcctgccagt acatcaataa tattgaagtt aaattggcca gtaataatgt
     6961 cgggacgaaa aacacctcgc tactaaccaa caattcaacc agcaacacga aagccagcgg
     7021 cattggcgtt ttaattgaag gtttgaaaag tagttcgagc gcccagatgg tactcaaacc
     7081 taacgactca agctcaattt ataaagatac caccaataac accggagacg gcagcccggt
     7141 aggaagcgcg acaaaatcgt tgtatttcca ggcaacctta aagcccgatg gtgacaatcc
     7201 aacaatcaat ccaggtgatt tcaaagccac cgctcaattt tcaatcacct atccgtaaaa
     7261 tcctataacg aaccgcaacg caatttgccc agaaaaggct aacgcttgcg gttctcttcc
     7321 cctacaatgc ggccattcta ttcatcaata ttatggccgg agaggttatg agcaaaccca
     7381 ctactatcgc tgtgctgcag aaatgcaaac aagagaaaaa gcgcttcgcc accattaccg
     7441 cgtacgatta cagcttcgcc aaactcttcg ccgatgaagg catcaatgtg atgctggttg
     7501 gcgactcgct gggcatgaca attcaggggc acgactccac cctgcctgtc accgtggaag
     7561 atatcgccta ccacacccgc gcggtacgcc gcggcgcgcc gaactgcctg ctgctctccg
     7621 acctgccgtt tatggcttac gccacgccgg aacaggcgtt tgaaaacgcg gctatcgtga
     7681 tgcgtgcggg ggccaacatg gtcaaaatcg aaggcggcgc atggttggtt gatacggtga
     7741 aaatgctcac cgaacgcgcc gtgccggtgt gtggccatct gggattaact ccccagtcgg
     7801 tgaatatctt cggcggctat aaaattcagg gccgcggcga tgccgggcag atactgctgg
     7861 atgatgcgct ggccttagaa gcagcgggcg ctcaactgct ggtgctggag tgcgtgccgg
     7921 ttgaactggc gaagcgcgtc acggaagcgc tgtcgattcc ggtgatcggc atcggcgcgg
     7981 gcaacgtcac cgacggtcag atcctggtga tgcacgatgc gtttggcatc accggcggtc
     8041 atattccaaa attcgcgaaa aatttccttg ccgaggcggg cgacatgcgc gccgccgtac
     8101 ggcagtatat ggcagaagtg gagtccggcg tttatccggg cgaagaacac agctttcact
     8161 aatttttctg accgtgccgg atagcgacgc gacgcgtctt atccggccta cagatcctca
     8221 acggatgtag gcctgataag cgcagcgcca tcgggctgga tcatcaagca actcaaggag
     8281 tcttgttgtg ttaatcattg aaaccctgcc gctgctgcgc cagcatattc gccgtctgcg
     8341 tcaggaaggc aaacgcgtcg cactggttcc cactatgggc aacctgcacg acggccatat
     8401 gaagctggtc gatgaggcaa aagcccgggc cgatgtggtc atcgtcagca ttttcgtcaa
     8461 cccgatgcaa tttgatcggc cggacgatct ggtgcgctat ccgcgcacgt tgcaggaaga
     8521 ttgtgaaaag ctgaacaaac gcaaagtcga ttatgtcttt gccccagccg ttgaggaaat
     8581 ctaccctcag gggctggaag gacagacata cgttgacgtt cccggcctct ctaccatgct
     8641 ggaaggcacc agccgtccgg gccacttccg cggcgtctcg accatcgtca gcaagctgtt
     8701 caaccttatc cagccggata tcgcctgctt tggcgagaaa gatttccagc agctggcgct
     8761 gatccgcaaa atggtggcgg atatgggtta tgacattgag atcgtcggtg tgccgattat
     8821 tcgcgctaaa gacggtctgg cgctcagctc acgtaacgct tatctgactg cagagcagcg
     8881 caaaattgcg ccgggtctat acaacgtgat gaatagcatc gctgaaaaac tgattgcggg
     8941 taatcgtgag ctgcaagaga ttattgccat tgccgagcag gaactgaatg aaaaaggctt
     9001 ccgtgccgac gacattcaaa tccgtgatgc cgacacgctg ctggagctga cggaaaccag
     9061 caaacgcgca gtgattctgg ctgccgcctg gctgggacag gcgcgtctga tcgataatca
     9121 aagcgttaca ttagcccagt agacaggggt taaaaatcgg gcaatactgc ctgagaattt
     9181 ccaaagcagg ctacaagcgc ctgcttagcc aagataaacg acagggtata gaagttatga
     9241 ttcgcaccat gctgcaaggc aagctccacc gcgtaaaagt cacgcaggcg gacctgcact
     9301 acgaaggctc ctgcgccatt gaccaggatt tccttgatgc ctccggtatt ctggaaaacg
     9361 aagcgattga tatctggaac gtgaccaatg ggaaacgttt ctcaacctat gcgattgcgg
     9421 ctgaacgcgg ctccagaatc atctcggtga acggtgcggc ggcgcactgc gctgaagttg
     9481 gcgacattgt gattatcgcc agcttcgtca ccatgtctga tgaagaagcg cgtacatggc
     9541 gtccgaaagt ggcctacttt gaaggcgaca acgaaatgaa gcgcaccgcg aaagccattc
     9601 cggttcaggt tgcctgatag tccttacccc tgcggctgat tgactatcag ccgcgacatc
     9661 gtttccagcg aatccgtgcg taaaatatac agccttttga gcagcatcgg attatctccc
     9721 ggcttcacct tccctctcac cgtggtgacc gccagatgga aaccggcgtc ttttgctgct
     9781 ttgatcgcgg tcgcgttata gccgccaaag ggataagaaa gataaaatac gtgcggagta
     9841 aactgtgtga gcgcccgccg cgaacgttca aaatcaaaca gaatattatg gtaactgcgg
     9901 ctatataaaa tcgggcggcg atgcccgtct acccggtgta aaaaatgggt atgcgactga
     9961 aaatcaaaaa catcgcttat cttgcgcaat tcggacacgc tcataaattg cagcgacctg
    10021 ggattccatt tttgcggatg gcgcttaata cgcgatgaga taataaatgc cgtcgctttc
    10081 atatcgtact gctttaatac cggatatgca tagcgactca ccgatttaag gccatcatca
    10141 aaggtgatag ccaccgcgcg cgccgggaaa ttagcgcggt tatagatgta atcctccagt
    10201 tggtacatcg tcaacgtggc atagccgcga tcgcgaagcc aggtcatttg gttgctgaat
    10261 gcccgaaccg aagtcgtggt ggaggtatgg cgaaaacggg tattctcttc atcacgtaaa
    10321 atgtgatgat aggtcaaaat cggaatgccg ttgtcttcct gcgcatccat ggcgttgaca
    10381 taagccagcc tgtcgccaat acggatctga ttccaggttt gatgtagccg gcctttcagc
    10441 ttgctaataa tggggtaacg caaattatcc accaatacgc caaacggggc gctactgatg
    10501 tccggcgcgt tatacaccgg cgtgtccttc caggtcacca gattctgatt gctgagcggc
    10561 ttgttaagat cgcccagccc atcttccact ttttgttttc cctgcacggg tcccagatgg
    10621 cctttatcga taaaccccac accgaagcca aatttaaagg cataataatc aaccgcaaca
    10681 ggcgttacgg aaagaatttg tccggcgcgg atattcccta cggtcaccat tttgtcgcca
    10741 atctgcgacc agatggcggc atctttcgtc gtttgcatat aacgagcggg caaggcagcc
    10801 aacacattac cggcgaaaaa gaacagcaag ataagaacaa cacgcataac catatatcat
    10861 aaccgaggcg aaaaaacgcc gttattgtag caaaagcgtc gtcaatggta ttgatcaaaa
    10921 ctcatacaaa tcatgcagca atacaaaagg cggatttttc tgctgctgat gccagagact
    10981 ggtgacatcc ggcgcgccaa gcgcgacaat ctggtcacga aatgctgaac tgctcatcga
    11041 ctctcgcaaa ggaatcattt cctctatcaa tgaatagcta atgcctgaaa taacttcaca
    11101 ttgaggatgt ttatggctca tcagcgacgc tacacgataa ggcgccgcgc cggaaatgtc
    11161 ggttaaaaat atcacgcctt caccggaatc ggtggcatgg agggcatcac acatcatgcg
    11221 gctcagcatg tttgagctca gaccgcgcca aaaattgacc gcccggcatt gcgccagcgg
    11281 accatttttt ctctccaggc gatcaagcat atcctgtgca cgatcgtcat ggcaggtaat
    11341 cacccaacct aacataacct acctccttag caggcaagta gtttatcagg gtgatcaatc
    11401 gggaatgatg acagccgtca aaagtctcct cttccctcca ggagaagagg agaatcgtat
    11461 cagctacgca aaccgcgtcc gcgctggatc agcgaccaac acagcagata gaaagtagcg
    11521 ataaagatca ccagtacgcc aaacgttgtc accagcggca catcatggat acccagaaaa
    11581 ccataacgga aaccgctgat catgtagacg atcgggttca ggtgcgacaa cccttgccag
    11641 aacggcggca gcagcgtcag cgagtaaaat accccgccga ggtaggtcag cggcgtcagc
    11701 acaaaggtcg ggatcagact gatatcgtca aaggttttgg caaacacggc gttcagcagt
    11761 ccggccagcg agaacagaat cgcggtcaga atcagcgtta gcgcgacaaa tacccaggaa
    11821 tgcacctgga aaggcacgaa aaagagcgaa atcgccgtca ccagaatccc cacgcacagc
    11881 ccgcgcgcca cgccgccgcc gacaaatccg gcgatgatca cgtgcgttgg caccggcgcg
    11941 accagcagtt cctcaatatt gcgctgaaac ttggcgctaa agaacgagga ggccacattg
    12001 gcgtaggagt tagtaatgac cgccatcata atcaggcccg gcacaataaa ttgcatatag
    12061 ctaaagccat gcatttcgcc gatgcgcgaa ccgatcaggt taccgaaaat aataaaatag
    12121 agcgtcatgg tgatgacagg cggcaccagc gtttgcaccc agatccgcat aaagcggtgg
    12181 atctctttcg cccagatgct tttaagggca acccagtaaa gctgcatcat gcgcgatctc
    12241 cttgtttttc atgcaccagc gacacaaaca gttcttccag acggttggct ttattacgca
    12301 tacttaatac ctgaaccccc tgctcgctca gttggctaaa gacgctgtta accccctgct
    12361 cgcgtaacac ttccacctcc agagtcgagg tatccaccag acgatattga taacccgtaa
    12421 gcttaggtag cgggcttttg ggcgctaaat ccagaataaa tgtctccgat ttcagctttg
    12481 aaagcagatt tttcatggaa gtattttcca ccagctcgcc gtgctgaata ataccgatat
    12541 tgcggcacag catttccgcc tcttccagat agtgggtggt gagaataatg gtggtgcctt
    12601 tggcgtttaa gtctttcagg aacccccaca ttgagcgacg taattcgata tcgacgcccg
    12661 ccgtcggctc gtcgagaatc aatagtttag gctcatgcat caatgcgcgg gcgatcatca
    12721 ggcggcgttt catcccaccg gacagcatcc gcgcgcgttc atgacgtttt tcccacagat
    12781 cgagctgttt taaatacttt tcgctacgta aaaccgcctc tttatgctcc acgccgtaat
    12841 aacccgcctg attcactacg atctgttgca ccgtttcaaa cgggttaaag ttaaactcct
    12901 gtgacaccag tccaagctgt cgcttggcgt taaccacgtc tttttccagg tcgtaaccaa
    12961 aaacgttaac gcgcccggac gttttattaa ccaatgagct gataataccg atggtggtcg
    13021 atttccctgc tccatttggc cccagaagcg cgtaaaaatc ccccgcttcg acctgcaaat
    13081 ctatgccgcg cagcgcctga acgccgccgg gataggtttt tttaagttgt tgaagttcca
    13141 gcgcaatggt cataaattct cacttacttt acgttcttac actttatata tggtttaaat
    13201 aattacggag ttgccctata ttagcccaac gcacttattt ggttacaggt cgttaacttc
    13261 catgaaagac atagatacac tcatcagcaa caatgcacta tggtcaaaaa tgctggtgga
    13321 agaggacccc ggattttttg agaaactggc gcaagcgcaa aaaccgcgct ttctatggat
    13381 tggatgttcc gacagccgcg ttcccgcaga gcgtttaacc gggcttgaac cgggcgaatt
    13441 gtttgttcac cgtaatgtgg ctaacctggt tattcacacc gatctgaact gtctctccgt
    13501 ggttcagtat gcggtagatg ctctggaagt tgagcatatt atcatttgcg gccactccgg
    13561 ttgcggcggt atcaaggctg cggtagaaaa ccctgagctg ggcttgatta ataactggct
    13621 gctgcatatc cgcgacatct ggcttaaaca tagctcgctg ttgggaaaaa tgcccgaaga
    13681 gcaacgtctg gacgcgctct atgaattgaa cgtcatggag caggtctata acctggggca
    13741 ttccaccatt atgcagtcag cgtggaaacg cgggcagaat gtgaccattc acggctgggc
    13801 gtacagtatc aatgatggcc tgctgcgcga tcttgacgtc accgccacca acagagaaac
    13861 gctggagaac ggctatcata agggtatctc cgccctaagt ctgaaataca ttccccacca
    13921 ataagccatt agctataggc cggataagtc gctttagcga cgccatccgg catttctgcg
    13981 cttactcgtc cagcagcacc actttaccaa catacggtag atggcgataa cgctgggcgt
    14041 agtcgatacc gtaaccgact acaaattcgt ccggaatcga aaagccaacg aactcaaccg
    14101 gcacgtccac ttctcggcga gacggcttat ccagcagcgt acaaatcgcc agcgatttcg
    14161 gctcgcgcag gcccaggatt tcacggacct tcgacagcgt attaccggaa tcaataatgt
    14221 cttcgacaat cagcacgtct ttaccacgaa tatcctcatc cagatctttg aggattttca
    14281 cgtcgcgggt ggtggacata ccgctaccat aactggaggc ggtcataaaa tcgacttcat
    14341 gaggaacctg aacttcacgg cacaggtccg ccataaacat aaatgagcca cgcaacagac
    14401 ctaccagcac catttcactg tcgctgtctt tataacgttc ggtaatctga cgacccagct
    14461 cggcaatacg tgctttgatc tccgcttcgg ggatca
//
LOCUS       DAJVKX010000118        14290 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.118, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000118 DAJVKX010000000
VERSION     DAJVKX010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14290
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.118"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            32..2436
                     /locus_tag="OPY25_003497"
                     /pseudo
     CDS             32..2436
                     /locus_tag="OPY25_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
     gene            2433..3062
                     /gene="dmsB"
                     /locus_tag="OPY25_003498"
     CDS             2433..3062
                     /gene="dmsB"
                     /locus_tag="OPY25_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HCS0929014.1"
                     /translation="MSQFTHYPPVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGR
                     RFRRVYEVKGGSFIPTGQGGVSNNVFAYTLSISCNHCADPVCTKNCPTTAMHKRPGDG
                     IVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGESPGCVATCPLE
                     AIKFGPIDELRAKYGSVCDVNGLPDSSITKPNLVVKAHQGAEKEGKRHA"
     gene            3055..3864
                     /locus_tag="OPY25_003499"
     CDS             3055..3864
                     /locus_tag="OPY25_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCS0929015.1"
                     /translation="MHELPLLIFTLCLQGSVGVTLWLALGRQYAVEGRVPARGALPAM
                     AGAFVLACVGLLASALHMGYPLNALNALRHVASSWLSREIVFASLYLAALGLGVVLLF
                     FRKPGWQPLLALAAAFGLVDVFCMAQVYIHASVATWQHSNTLALFFGTSGIIGSVVIA
                     LAYLRNAGAAMRCAVVVVALMVLIRLIMQPLWLADINAVDTTVVTFPHHPLQALAQLR
                     DIYLLGWCVSAAGMLCFAAGGLRNARGTLVAGSVLLLIGEIMLRYVFFSIG"
     gene            3864..4727
                     /locus_tag="OPY25_003500"
     CDS             3864..4727
                     /locus_tag="OPY25_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCS0929016.1"
                     /translation="MVNLTIDPAVDVTQACVRRRFRFSSCRACTDVCPAQVFSLAQGQ
                     VSIDTTRCIACGDCLFVCPVDAITDIKPVKRFVQGDTLVGPFSLQAPTVDELLLWHSQ
                     YGIRFIDIAVERSAQWLMALAGLNLALRRYGEPGWSFKHVVGAEINASRRTLFHVPRD
                     AITPCAVEPGKRRLRQAFSAFSECVPEISPQECRMCGACWRSCPENVIQFDDDTLTIA
                     AARCTGCGGCAAVCPHQALRLRFDVEPASTRHSAVHTLTCESCKRTFHALTPEHTHCV
                     LCQSPEFAVRL"
     gene            4848..5279
                     /gene="ndk"
                     /locus_tag="OPY25_003501"
     CDS             4848..5279
                     /gene="ndk"
                     /locus_tag="OPY25_003501"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000963848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCS0929017.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSLESAQREIAFFFGEGEVCPRTR"
     gene            5486..6652
                     /gene="trmG/rlmN"
                     /locus_tag="OPY25_003502"
     CDS             5486..6652
                     /gene="trmG/rlmN"
                     /locus_tag="OPY25_003502"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HCS0929018.1"
                     /translation="MSEQIVTPESSTPVVLNNETKINLLDLNRQQMREFFKNLGEKPF
                     RADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIA
                     VGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAA
                     KIVGAAKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSG
                     VVPALDKLGDMIDVALAISLHAPNDTIRDEIVPINKKYNIETFLGAVRRYLEKSNANQ
                     GRVTIEYVMLDHVNDGTEHAHQLAELLKETPCKINLIPWNPFPGAPYGRSSNSRIDRF
                     SKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEVIDIKAI"
     gene            6946..7920
                     /gene="rodZ"
                     /locus_tag="OPY25_003503"
     CDS             6946..7920
                     /gene="rodZ"
                     /locus_tag="OPY25_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HCS0929019.1"
                     /translation="MNTEATHDQNEAQTTGVRLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPSDLASTFLRGYIRSYARLVHVPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMSFTWLVLFVVVGLTGAWWWQNHKAQQEEITTMADQSTAELNADKDS
                     GQSVPLDTSAATSQDTTPAQTAPAPATPVDSTAATQNTVVAPSQANVDTAATSAAPAA
                     TETPSALPTSQAGVAAPAADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLT
                     GQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEPTPAQ"
     gene            7947..9065
                     /gene="ispG"
                     /locus_tag="OPY25_003504"
                     /gene_synonym="gcpE"
     CDS             7947..9065
                     /gene="ispG"
                     /locus_tag="OPY25_003504"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HCS0929020.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVSVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNDDMIAQLESRIRAKVSQLDEARRIDVLQVEK"
     gene            9176..10450
                     /gene="hisS"
                     /locus_tag="OPY25_003505"
     CDS             9176..10450
                     /gene="hisS"
                     /locus_tag="OPY25_003505"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCS0929021.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VSLELNSIGSLEARANYRDALVAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQAL
                     LNDAPVLGDYLDDDSREHFAGLCKLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLV
                     AAGAQTQSAAMTLAERLRDEMPGVKLMTNHGGGNFKKQFARADKWGARIALVLGESEV
                     ADGTVVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            10464..11084
                     /locus_tag="OPY25_003506"
     CDS             10464..11084
                     /locus_tag="OPY25_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfgM family protein"
                     /protein_id="HCS0929022.1"
                     /translation="MEIYENEHDQVDAIKRFFAENGKALAVGVILGVGALVGWRYWSS
                     HQTESARAASLAYQNAVTAVSADKPDSIPAAEKFAAENKNTYGALASMELAQQFVDKN
                     ELKKAEAQLQQGLAATSDENLKAVINLRLARVQLQLKQADAALKTLDAVKGEGWTAIV
                     ADLRGEALLSKGDKKGARSAWEAGVNSDASPALSEMMQMKINNLSI"
     gene            11095..12273
                     /gene="bamB"
                     /locus_tag="OPY25_003507"
     CDS             11095..12273
                     /gene="bamB"
                     /locus_tag="OPY25_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HCS0929023.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFSGEEDVVKMSPLPQVENQFTP
                     TTVWSTSVGNGIGEFYSNLHPVMADNVVYAADRAGVVKALNADDGKEIWSVNLGEKDG
                     WFSRSSALLSGGVTVAGGHVYIGSEKAEVYALNTSDGTTAWQTKVAGEALSRPVVSDG
                     IVLIHTSNGQLQALNQADGAIKWTVNLDMPSLSLRGESAPATAFGAAIVGGDNGRVSA
                     VLMQQGQMIWQQRISQATGPTEIDRLSDVDTTPVVVNGVVYALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGDRIYLVDQNDRVLALTTDGGVTLWTQSDLLHRLLTSPVLYN
                     GDLVVGDSEGYLHWINVDDGRFVAQQKVDSSGFLTEPTVADGKLLIQAKDGTVYAITR
                     "
     gene            12392..13864
                     /gene="der"
                     /locus_tag="OPY25_003508"
     CDS             12392..13864
                     /gene="der"
                     /locus_tag="OPY25_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCS0929024.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMDDVAPQEEVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHTGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMG
                     TPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK"
     gene            13953..14174
                     /locus_tag="OPY25_003509"
     CDS             13953..14174
                     /locus_tag="OPY25_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCS0929025.1"
                     /translation="MEIICPVCHHALERNGDTAHCETCAKDFSLQALCPDCRQPLQVL
                     KACGAVDYFCQNGHGLISKKRVNFVISDQ"
BASE COUNT         3241 a         3630 c         4181 g         3238 t
ORIGIN      
        1 atcaagagaa ccaacgcata aaaacgtgag aatgggtttt tatttgacga gtcggatcat
       61 gaaaaatata aaaagccagg gaaatggcga acagcccgct atttctcacc gccattttat
      121 ccaggccagc tccgcgctta ttgagttacc gtttgtctcc tcgccagcta ccgctcaggc
      181 gcgcgctgtg acggcaactg aaaacaggcc tgcggaaaaa gtcgttcaga catgcagcac
      241 ttttgactgc gggggcaaat gcgatattcg ggcgcatgtc agtgacggta tcgtgacgcg
      301 aatttcaacg cgaccggata acgcgctgga tgcgcaaatg ccggtgatgc gtgcctgtgt
      361 tcgtggacga gcataccgta aatttgttta tcatcctgac agacttaaat atcccatgaa
      421 gcgcgtagga aaacgcggtg aaggaaagtt cgagcgaatt tcctgggatg aagcgacaac
      481 cttaatcgcc gataatttaa aatcgattac tgaaaaatat ggcccggctt cgcgctatgt
      541 tcatgttggt accgccgttt ccggcggcac cttttccggc gataaaatgg cgcgtcgcct
      601 gctgaatctt accggcggct atctcgaaag ctaccattcg gtgagtatgg gcaacacggt
      661 ggccgcgacg ccttatactt acggcattgc cgccagcggc agttcgctgg atacgctttt
      721 ggacaccaaa ctggtgattc tgtggggcca taacccgacg gagaccattt ttggtcatac
      781 caactatttc ttgcagaaga tgaagcagaa cggtacgcgg tttatcgtgg ttgatccgcg
      841 ctattccgac accgtttcgt cgctggcgga tcagtggatc ccgctgctgc ccaccaccga
      901 caatgcgctg atggacgcga tgatgtacgt catcatcagc gagaatctgt acgatcgtgc
      961 atttattgcg cgctacgcta tcggttttga cgaagactca atgccggaag gcgtaccggc
     1021 taacgaatcg ctggtggcat atctgaccgg cgccaaagac ggtgtcgtta agtctcccga
     1081 gtgggcggaa aagatcaccc atgtgccggc gcaaaccatt cgccagttag cgcgtgatta
     1141 cgcgaagacc aaacctgccg cgttgattca ggggcggggc cacagcgcca caactgcggc
     1201 gagcgcaccg cgcgcggctc gactctactg gcgaccatta ccggtaatgt cggcatcaaa
     1261 ggcggttggg ctgcgggtta cggcggctgc gctaaccgta aatttgccgc gggtccggag
     1321 atgccggata acccggtaaa agccaaaatt tcggtgatga actgggtgca ggccgcagac
     1381 gacgccagca aagtgacgcc ggatatgggg ctgaaagatg ccgataagct ggacagtaac
     1441 atccgtattc tgttctcgct ggccgggaac tatctggcga atcagaaccc cgatctgcac
     1501 caggcggtac gcgtactgga ggatgaatca aagatccagt ttattgtcgc cagcgatctg
     1561 tttatgacgc cgagcgcgaa atacgccgat ctactgctgc cggaaaccag ctttatggaa
     1621 cgttggaaca tcggtgaaac ttggggcacg gcaagctacc tgatactctc tgaaaaactg
     1681 atcgagcctg aatttgagcg tcgctccgac tacgactggc tacgtgaggt ggcggcgaaa
     1741 ttaggcattg agaatgaatt tagccagggg cgcgatgaga aagcgtggat tgaacacatc
     1801 tgggaacaga cgcgcctggc gatgccggac gaaaatctgc cggattttgc cacactgcaa
     1861 aagacccgtc agcatctgtt caaaagcgcg ccatttatcg cctttgaaga caatattcgc
     1921 gatccggaca atcatccgtt cccgacgccg tcagggaaaa tagaggtctt ctcgaagcgc
     1981 ctgtacgaca tgcagcatcc ggaaatcccg gcgttgtcgc actacgttcc cgcgcatgaa
     2041 ggcccggagg atgcgctggt gaaagatttt ccgctccagt taattacgtg gaaaggaaaa
     2101 aaccgcgcca actcaacgca atacgctaac ccgtggctga ttgaagtgca gcagcagaca
     2161 ttgtggatca acccgcagga tgcgcaaacg cgcggcatta cgcatggcga catggtgcgc
     2221 attcataact cacgcggaat ttgcgaaatc ccggcggaag tgacgccgcg cattattccc
     2281 ggcgttgtcg cgatgcaggc tggcgcctgg tggcagccgg atgagaacgg tattgataaa
     2341 ggcggctgcg cgaacgtcct cagctcggcc cgtattaccg ccctggcgaa gggaaattca
     2401 catcaaacca tgctggtgga ggtggcaaaa gcatgagcca gtttacacat tacccgccgg
     2461 tgagcgataa acaactggga tttttcatcg actcctcacg ctgctccggt tgtaaagcct
     2521 gccaggtggc ctgcaaagac aaaaacaatc tggaagtagg ccgtcgtttc cgccgcgtct
     2581 atgaagtcaa gggcggaagt ttcatcccga ccgggcaggg cggggtcagc aataacgtat
     2641 ttgcttatac gctttctatt tcctgcaacc actgtgcgga tcctgtctgc accaaaaatt
     2701 gcccgactac cgctatgcat aaacgcccag gtgacggcat tgtgcgcgtt gataccgaca
     2761 aatgcgtcgg ctgtggctat tgcgcctggt cctgccctta tggcgcgccg cagcttaacg
     2821 agcagaccgg ccaaatgtcc aagtgcgaca tgtgcgttga tttactggcg aaaggtgaat
     2881 cgcccggctg tgtcgcgacc tgtccgctgg aggccatcaa gtttggcccg attgatgaac
     2941 tgcgcgcgaa gtacggtagc gtatgcgacg ttaacgggct gccagattca tccataacca
     3001 aacctaatct ggttgtcaaa gcgcatcagg gcgcagaaaa agagggtaaa cgccatgcat
     3061 gagttaccgc tgctgatttt tacgctctgt ttgcaagggt ccgtgggcgt gactctgtgg
     3121 ctggcgctgg gccgtcagta cgccgtagag ggacgcgtac ctgcgcgcgg cgcgcttccc
     3181 gcgatggcgg gggcgtttgt actggcctgc gtggggctgc ttgcttcagc gctgcacatg
     3241 ggctatcccc tgaatgcgct aaacgcgtta cgtcatgtcg ccagttcgtg gctgagtcgc
     3301 gaaatcgtct ttgccagcct ttatctggcg gcgctggggc tgggggttgt gctgctgttt
     3361 ttccgaaagc ctggctggca gccgctgctg gcgctggcgg cagcgttcgg gctggtggat
     3421 gtattctgca tggcgcaggt ttatatccat gcctcggtgg cgacctggca gcatagcaac
     3481 acgctggcgc tgttctttgg cacgtcaggc attatcggct cggtagtcat tgcgctggct
     3541 tatctgcgca acgctggcgc cgcaatgcgc tgcgctgtgg tggtggtcgc actgatggtg
     3601 ctgattcgcc tgatcatgca gccgctatgg ttggcggata ttaatgcagt ggatacgacg
     3661 gtcgtcactt tcccgcatca tccgctacag gcgctggcgc agttgcgcga catctatctt
     3721 ctcggctggt gtgtctcagc ggcgggaatg ctctgctttg ccgcaggcgg tctgcgaaac
     3781 gccagaggga cgctggtggc gggcagcgta ttgctgctta tcggcgagat tatgctgcgc
     3841 tacgtcttct ttagtattgg ctgatggtta acctgacgat cgatccggcg gtagacgtga
     3901 cgcaggcctg cgtccgtcgt cgctttcgtt tttcttcctg ccgcgcttgc actgatgttt
     3961 gtccggcgca ggtgttttcg ctggcgcagg ggcaggtcag catagatacg acgcgctgca
     4021 tagcctgtgg cgactgtctg tttgtctgtc ctgttgacgc cattaccgat atcaaaccgg
     4081 ttaaacgctt tgtgcagggg gatacgttgg tggggccgtt ttcgctacag gcgccaacgg
     4141 tcgatgaact gcttctctgg cacagccagt acggtattcg ctttattgat attgcggtgg
     4201 agcgatcggc gcagtggctg atggcgttgg cggggctaaa tttagcgctg cgccgctacg
     4261 gcgagccggg ctggtctttc aaacacgttg tcggcgcgga aattaatgcc tcgcggcgca
     4321 ctctgtttca tgttccgcgc gacgccatta ccccgtgcgc cgtcgagccg gggaaacggc
     4381 gtctcagaca ggcgttttcc gcgttcagcg aatgcgtacc cgaaatcagt ccgcaagagt
     4441 gcaggatgtg cggcgcctgc tggcgaagct gcccggaaaa cgttatccag tttgacgacg
     4501 acacgctgac gatagcggcg gcgcgttgta cgggatgcgg cggctgtgcg gcggtatgtc
     4561 cgcatcaggc gctgcggctg cggtttgacg tggaacccgc ctcaacgcgg catagtgcgg
     4621 tgcatacgct cacctgcgaa agctgcaaac gtactttcca tgctctcacg cctgaacaca
     4681 cgcactgcgt gctgtgtcag tcccctgagt ttgctgtgcg cctttaactt ttgttgctaa
     4741 tgctcatttt attttaaaaa aatgttacct gcatccatag gcaattgatg ggatgctctt
     4801 tataatccgc gcctgacata acaacagaac atatttcaga ggtaaacatg gctattgaac
     4861 ggactttttc catcattaaa cccaacgcgg tggcaaaaaa cgttattggc agcatctttg
     4921 cgcgctttga agctgcaggg ttcaaaattg ttggcactaa aatgctgcac ctgaccgttg
     4981 agcaggcgcg cggcttctat gctgagcacg acggcaagcc gttctttgac ggtctggtgg
     5041 agttcatgac ctctggccct atcgtggtat ccgtgctgga aagtgaaaat gcggtacagc
     5101 gtcatcgcga tctgcttggt gccaccaatc cggcgaacgc gttggcgggg acgctgcgtg
     5161 ctgattacgc tgacagcctg accgaaaacg gcacccacgg ttcggattcg ctggaatccg
     5221 cgcagcgcga aatcgccttt ttcttcggtg aaggcgaagt gtgcccgcgc acccgttaat
     5281 ctccttcgtc tttcacgctg taaatgcgtt ggcgataaat tatcggttca aatattattt
     5341 ttgctaatgc cgcgtgcaga cgtggcatcc ttacgccaga atttgtacaa tgcagcgccc
     5401 ccggacgagc agtaagctta ccggggcgtt tcttttttca accctccagg ggccataacg
     5461 tgtaataacg aggccggaat agcatatgtc tgaacaaatt gtcacacctg aaagcagtac
     5521 cccggtagtt cttaacaacg aaacaaaaat caacctgctg gatctaaacc gtcagcagat
     5581 gcgcgagttt tttaaaaact taggtgaaaa acctttccgc gccgatcagg tgatgaaatg
     5641 gatgtatcac tattgctgcg ataattttga tgagatgacc gacatcaaca aagtgttgcg
     5701 cggcaaatta aaagaggtcg cggaaattcg cgcgccggag gtcgttgaag agcagcgttc
     5761 ttcagacggc accatcaagt gggcgattgc tgtcggcgat cagcgcgttg aaacggtcta
     5821 catcccggag gacgaccgcg ctacgctgtg tgtctcttca caggtagggt gcgcgctgga
     5881 gtgcaaattt tgttcaactg cgcagcaggg ctttaaccgc aacctgcgcg tatcggaaat
     5941 tatcggtcag gtctggcgtg cggcgaaaat cgtcggcgcg gccaaagtca ccggccagcg
     6001 tccgatcacc aacgtagtca tgatgggaat gggcgagcca ttgcttaacc tgaccaatgt
     6061 cgtaccggcg atggaaatta tgctcgatga ctttggtttc ggcctgtcca aacgtcgtgt
     6121 cacgctctca acgtccggcg tggtgcctgc gctggataaa ctgggcgata tgatagacgt
     6181 cgcgctggct atctccttac atgcgccgaa tgacactatt cgcgacgaaa tcgtcccgat
     6241 caacaaaaaa tataatatcg aaacgttcct gggcgcggtt cgccgctatc tggagaaatc
     6301 caacgccaat caggggcgcg tgacgattga atacgtgatg cttgaccacg ttaacgacgg
     6361 cactgaacac gcgcatcaac tggcggagct actaaaagag acgccttgta agattaatct
     6421 gattccgtgg aacccgttcc ctggcgcgcc gtatggccgc agctctaaca gccgtatcga
     6481 tcgcttttct aaagttttga tgagttatgg tttcacgacc atcgtacgca agacgcgtgg
     6541 cgatgacatt gatgcggcat gcggacagtt ggcaggcgat gtgattgacc ggactaaacg
     6601 tactctgcgt aagcgtatgc agggagaggt gattgacatc aaggctattt gatagcagtt
     6661 gcgccacggg gcattcatta taccgtggcg caatgtcagt tgaataatgt ctggcgttgt
     6721 acttgtctgg tcaataataa cggtgcgttt ttgtcgactt taaggcagta tgtaacgatg
     6781 caacaagagt ttaaccttgt gtcttaagcg gttttgtcat ctgcggcctg acaggcttat
     6841 actgtctgac taaaggttaa ctaacctgat gtttcgcggt gtgggcgggc attacggctc
     6901 gtcggcgcct gaatcctaat ttacacgtac ctgtagctgt agcgaatgaa tactgaagcc
     6961 acgcacgacc aaaatgaagc acaaaccacc ggcgttcgtc tgcgcaatgc ccgtgaacaa
     7021 ctcggactca gccagcaggc tgtcgctgag cgactttgcc tgaaggtttc tacggtacgc
     7081 gatattgaag aagataaggc gccgtccgat cttgcttcaa ccttcctgcg cggatatatc
     7141 cgctcatatg cgcgtctggt gcatgttcca gaagaggaac tgctgccggg gctggaaaaa
     7201 caagctccgc tgcgcgccgc taaagtcgcc ccgatgcaga gtttctcatt aggaaagcgt
     7261 cgtaaaaaac gcgacggctg gttaatgtct tttacctggc tggtactgtt tgtggtcgta
     7321 gggctgaccg gcgcctggtg gtggcagaac cacaaggcgc agcaggaaga gatcacgaca
     7381 atggccgatc aaagcacggc tgaactgaac gcagataaag acagcggcca aagcgtaccg
     7441 ctggacacca gtgccgcgac aagccaggat acgacgccag cgcaaacggc tccggctcct
     7501 gcgacgccgg ttgattcgac ggcggcaacg caaaatacgg tagtcgcgcc ttcgcaggcg
     7561 aatgtcgata cggctgcgac atctgccgcg ccagcggcaa cggaaacgcc gtccgcgctg
     7621 ccgaccagtc aggctggcgt agcggcgcct gctgccgatc cgaacgcgct ggtgatgaat
     7681 tttaccgctg actgttggct cgaagtcact gacgccacgg gtaaaaaact gtttagcggt
     7741 atgcagcgta aagatggcaa tttaaaccta accggtcagg cgccttataa acttaaaatt
     7801 ggcgcgccgg ccgcggtgca gatccagtat caaggaaaac ctgtcgatct gagccgcttt
     7861 atcagaacta atcaggttgc gcgtctgacc cttaatgccg aaccgacacc ggcgcagtaa
     7921 cagacgggta acgcgggaga tttttcatgc ataaccaggc tccgattcaa cgtagaaaat
     7981 cgacacgtat ttacgttggg aatgtgccga ttggcgatgg cgcccctatc gccgtccagt
     8041 cgatgactaa cacgcgtacc actgacgtgg aagcgacggt taatcagatc aaagcgctgg
     8101 agcgcgttgg cgcagatatt gttcgtgttt ctgtaccgac catggacgcc gccgaagcgt
     8161 tcaagcttat caaacagcag gttagcgtcc cgctggttgc cgatattcac ttcgactacc
     8221 gcattgcgct gaaagtagcg gaatacggcg ttgactgctt gcgtattaac cccggcaata
     8281 tcggtaacga agaacgcatt cgcatggtgg tggactgcgc gcgcgacaaa aacatcccta
     8341 tccgtatcgg cgtaaatgcc ggatcgctgg aaaaagatct gcaggaaaaa tacggagagc
     8401 cgacgccgca ggcgctgctg gaatcagcca tgcgccatgt cgatcatctc gatcgtctca
     8461 actttgatca gttcaaagtg agcgtaaaag cgtccgatgt attccttgcc gttgagtctt
     8521 atcgtttgtt ggctaaacag atcgatcagc cgctgcatct ggggatcacc gaagcgggcg
     8581 gcgcgcgtag cggggcggtt aagtcggcga tcggtttagg tctgctgtta tcggaaggca
     8641 tcggcgacac gctgcgcgta tcgttggcgg ccgacccggt ggaagagatc aaagtcggtt
     8701 tcgatatcct gaagtcgctg cgtattcgcg cgcgcggcat caatttcatc gcctgcccga
     8761 cctgttctcg tcaggagttc gacgttatcg gcacggtgaa cgcgctggag cagcgtctgg
     8821 aagatatcat caccccgatg gacgtctcga tcatcggttg tgtggtgaac gggccgggcg
     8881 aagcgctggt atcgacgctg ggcgtgacgg gcggcaataa gaaaagcggc ctgtatgaag
     8941 acggcgtgcg taaggacaga ctcgataacg acgatatgat cgcgcagctt gaatcccgta
     9001 ttcgcgcgaa agtaagtcaa cttgatgaag cgcgtcggat tgacgtgctg caggttgaaa
     9061 aataagaacg tgatgggaag cggcgcgctt cccgtgtatg attgaacccg catggctccc
     9121 ggttcgttcg gggaagcgct gagggttcat ttttatattc agaaagagaa taaacgtggc
     9181 aaaaaacatt caagccattc gcggcatgaa cgattatctg cctggcgaaa ccgccatctg
     9241 gcagcgcatt gaaggcacac tcaaaaacgt gctcggcagc tacggttaca gtgaaatccg
     9301 cttgccgatt gtagagcaga ccccgttatt caaacgcgcg atcggtgaag ttactgacgt
     9361 ggttgaaaaa gagatgtaca cctttgagga tcgcaacggc gatagcctga cattgcgccc
     9421 tgaaggtacg gcgggctgtg tacgcgccgg catcgaacat ggtctcctgt acaatcagga
     9481 acagcgtttg tggtatatcg ggccgatgtt ccgtcatgag cgtccgcaaa aaggccgcta
     9541 ccgtcagttc catcagctag gcgccgaagt ctttggctta caaggcccgg atatcgacgc
     9601 ggaactgatt atgctgaccg cacgctggtg gcgcgcgctg ggcatctctg aacacgttag
     9661 cctggagctg aactctattg gttccttaga ggcgcgtgcg aactatcgcg atgcgctggt
     9721 cgcgttcctc gaacagcatc aagagacgct ggacgaagac tgcaaacgcc gtatgtatac
     9781 caatccgcta cgcgtgctgg attcaaaaaa tccggacgtg caggcgctgc tcaacgacgc
     9841 gcctgttctc ggcgactatc tcgatgacga ttcacgcgag cactttgccg gcctgtgtaa
     9901 attgctggac gcggcgggga ttgcctacac cgtcaaccag cgtctggtac gcggtctgga
     9961 ttactacaac cgcaccgtat ttgaatgggt aacaaacagt ctggggtcac aaggcaccgt
    10021 ctgtgcgggt ggtcgttatg atggtctggt ggaacaactg ggcggtcgcg ctaccccggc
    10081 agtgggcttt gcgatgggcc tggaacgact tgttttgtta gttcaggcag ttaatccgga
    10141 atttattgcc tctcctgttg tcgatatata cctggtagct gccggcgcac aaacgcagtc
    10201 tgcggcaatg acgctggcgg agcggctgcg cgatgaaatg ccaggcgtga agctaatgac
    10261 aaaccacggc ggcggcaact ttaagaaaca gtttgcccgc gccgataagt ggggcgcccg
    10321 tattgcactg gttcttggcg aatctgaagt cgccgatggg actgttgtag tgaaggattt
    10381 gcgctccggt gagcaaacgg cagtggcgca ggacagcgtc gccgcgcatt tgcgcacttt
    10441 attgggctaa ggagaaggac agcgtggaaa tttacgagaa cgaacacgac caggtggatg
    10501 cgattaaacg cttctttgcc gaaaacggca aagcgctggc tgtcggagtg attttagggg
    10561 ttggcgcgct ggttggctgg cgttactgga gcagccatca gacggagtcc gcgcgtgctg
    10621 cttctctggc gtatcaaaat gcggtgacgg cggtaagcgc cgataagccg gatagcattc
    10681 ccgccgctga aaaattcgcg gctgagaata aaaataccta tggtgcgctg gcgtctatgg
    10741 aactggcgca gcagtttgtg gataagaatg aacttaaaaa agccgaagcc cagttgcagc
    10801 aggggttggc ggccaccagc gatgaaaatc tcaaagcggt gattaatctg cgtctcgctc
    10861 gcgttcagtt acagcttaag caagctgacg ccgcgctgaa aactctggat gccgttaaag
    10921 gcgaaggatg gacggcaatt gtcgctgatt tgcgcggcga agcgttgctg agtaagggtg
    10981 ataaaaaagg cgcgcgcagc gcatgggaag cgggcgtcaa tagcgatgct tctccggcgt
    11041 tgagcgaaat gatgcagatg aaaatcaata atttgtccat ctgagaggga cccgatgcaa
    11101 ttgcgtaaat tacttctgcc agggttgctt tccgttaccc tgctcagcgg ctgttcactg
    11161 tttagcggcg aagaagatgt cgtcaagatg tctccattac cgcaggttga aaaccagttt
    11221 accccgacca ctgtctggag cacctctgtc ggtaacggaa ttggtgaatt ttattctaac
    11281 cttcatccgg taatggcaga taacgtggtc tatgcagccg atcgcgcggg cgtggtaaaa
    11341 gcgctcaatg cggatgatgg caaagagatc tggtctgtga atctgggcga gaaagacggc
    11401 tggttctctc gttcgtccgc gctgttgtcc ggcggcgtca ctgtcgcggg cggtcacgtc
    11461 tatatcggca gtgaaaaggc cgaggtttat gcgctgaata ccagcgacgg taccacagca
    11521 tggcagacga aggtcgcagg cgaagcgttg tctcgcccgg ttgtcagtga tggaatcgtc
    11581 cttatccata ccagcaacgg tcagttgcag gcgctaaatc aggcggatgg cgccattaaa
    11641 tggacggtga acctggatat gccttcgctg tcgctgcgcg gcgaatctgc gccggcaacc
    11701 gcgttcggcg cggctatcgt tggtggtgat aatggccgcg tcagcgccgt gttgatgcaa
    11761 caagggcaga tgatttggca gcagcgtatc tcccaggcca ctggcccaac ggaaattgac
    11821 cgtctgagcg acgtcgatac cacgccggtt gtggtaaacg gcgtcgttta cgcgttggcg
    11881 tataatggta acttaacggc gctggatctg cgcagtggtc agattatgtg gaaacgcgag
    11941 ctggggtcgg tcaatgactt tatcgtcgac ggcgaccgta tctacctggt cgatcagaac
    12001 gatcgtgtgc tggcgctgac cactgacggc ggcgtaacgc tgtggacgca aagcgatctg
    12061 ctgcaccgtt tgctgacctc cccggtactg tataatggtg atttagtcgt cggcgatagc
    12121 gaaggttatc tgcactggat taatgtcgat gacgggcgtt ttgtggccca acaaaaagta
    12181 gacagttccg gttttctgac cgaaccgacg gtggcggatg gtaaactgct catccaggcc
    12241 aaagacggta cggtctacgc gattacgcgt taatcgtcac ggttgtgcgt ttgaaaaaac
    12301 ggctcctggt gtaggggccg ttttcctgtt tttaacaacg gcgtaaaaat gacgcgcgtt
    12361 gtctgatgat tttttaaatg aggctttaaa catggtacct gtggtcgcgc ttgtcgggcg
    12421 ccctaacgtc ggaaaatcca cgctatttaa ccgtctgacc cgcacccgag atgcgttggt
    12481 tgcggatttc ccgggtctga ctcgtgaccg taagtacggt cgtgcggagg ttgaaggccg
    12541 cgagtttatc tgtatcgaca ccggcggtat tgacggcacc gaagacggcg tcgaaacgcg
    12601 gatggcggaa cagtcgctgc tggcgattga agaagcggat gtggtgttat tcatggtaga
    12661 tgcgcgcgct ggtctgatgc cggcggatga agcgattgcc aaacatctgc gctcccgtga
    12721 aaaaccgacc ttcctggtgg cgaataaaac ggatggtctc gatcctgatc aggcggttgt
    12781 cgatttttac tcgctgggat taggcgaaat ttatcctatc gccgcctcac atggtcgcgg
    12841 cgtattgagc ctgctggaac atgtgcttct gccgtggatg gatgatgtcg caccgcagga
    12901 agaagtggat gaagacgcgg aatactgggc gcagttcgag gcggaacaaa atggcgaaga
    12961 agcgccggaa gatgattttg acccgcaaag cctgccgata aagctagcga ttgtcggtcg
    13021 cccgaacgta ggtaagtcca cactcactaa ccgtattctc ggcgaagagc gcgtggtggt
    13081 atacgacatg ccgggcacca ctcgcgacag tatttatatc ccgatggaac gcgacgaacg
    13141 ggaatatgtg ctgattgaca cggcgggggt gcgtaagcgc ggaaaaatca ccgatgcggt
    13201 agaaaagttc tcggtgatta aaacgttaca ggcgattgaa gacgctaacg tcgtactgtt
    13261 ggttatcgat gcgcgcgagg ggatctctga ccaggatttg tctctgctgg gctttatcct
    13321 caatagtggg cgctcactcg ttatcgtagt caacaaatgg gatggcctga gccaggaagt
    13381 caaagagcag gtgaaagaga cgctggattt ccgtctgggc tttattgatt ttgcccgcgt
    13441 gcactttatc tctgcgctgc acggcagcgg tgtcgggaac ctgtttgagt ccgtacgcga
    13501 ggcttacgac agttccactc gccgggtgag cactgcgatg ctgacccgta tcatgacgat
    13561 ggcggtggaa gatcatcagc cgccgctagt gcgcggtcgc cgtgtgaagc tgaaatatgc
    13621 ccacactggc ggctataacc cgccgattgt ggttattcac ggcaaccagg taaaagatct
    13681 gccagactcc tataagcgct atctgatgaa ctacttccgc aagtcgttgg aagtgatggg
    13741 tacgccgatt cgcattcagt ttaaagaagg ggagaacccg tatgcgaaca agcgtaacac
    13801 actgacgcca acgcaaatgc gcaaacgtaa gcgtctgatg aagcatatca agaaaagcaa
    13861 gtaatgcttt ttcagtaata ttccaggcct gataagcgca gcgctatcag gcctttcaag
    13921 taaaagcgag tcacgcgcct gaggagaatg ttatggaaat aatctgccct gtttgccatc
    13981 atgcgctgga gcgcaatggc gatacagccc attgcgagac atgcgctaag gatttctcgt
    14041 tacaggcact ttgtcctgac tgccgccagc cgttacaggt tttgaaagcc tgcggcgcag
    14101 tggactattt ttgccagaac ggtcatggtt taatttcaaa aaaacgggtt aatttcgtca
    14161 tttccgatca ataaaaccac tgtcgacgtt gcgtcgcaga gcagaggcgc cgacgtctta
    14221 tccggctaag ggcaaaagcg ttattctata ctcccgtaat atcagcatag taccctgccc
    14281 ggcggttatt
//
LOCUS       DAJVKX010000119        13677 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.119, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000119 DAJVKX010000000
VERSION     DAJVKX010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13677
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.119"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..108
                     /locus_tag="OPY25_003510"
     CDS             <1..108
                     /locus_tag="OPY25_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309858.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HCS0929026.1"
                     /translation="AGRKSGQHSGGNFKNDPQRASEAGKKGGKSSNRNR"
     gene            245..883
                     /gene="rutR"
                     /locus_tag="OPY25_003511"
     CDS             245..883
                     /gene="rutR"
                     /locus_tag="OPY25_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HCS0929027.1"
                     /translation="MSQRTEKKIGKRSQATGAKRQLILTAALAVFSQYGIHGARLEQV
                     AERAGVSKTNLLYYYPSKEALYVAVMRQILDVWLAPLKAFRAEFSPLEAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVHSGKLAPVSPH
                     HLIFMIWAATQHYADFAPQVEAVTGATLRDEAFFNQTVESVQRIIIEGIRVR"
     gene            complement(880..1275)
                     /locus_tag="OPY25_003512"
     CDS             complement(880..1275)
                     /locus_tag="OPY25_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HCS0929028.1"
                     /translation="MKRIFLTCAALLFSSQALADECASASTQLEMNRCAAAQYQAADK
                     KLNETYQSAIKRAQPPQRELLQKAQVAWIALRDADCALIRSGTEGGSVQPMIASQCLT
                     DKTNEREAFLASLLQCEEGDLSCPLPPAG"
     gene            complement(1334..5296)
                     /gene="putA"
                     /locus_tag="OPY25_003513"
     CDS             complement(1334..5296)
                     /gene="putA"
                     /locus_tag="OPY25_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HCS0929029.1"
                     /translation="MGTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKL
                     ENSDTLPELPALFAGAANESEEPVAPQDEPHQPFLEFAEQILPQSVSRAAITAAWRRP
                     ETDAVSMLMEQARLSPPVAEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGR
                     LVSTHNEANLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAQALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGLNIDAEEADRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLVDLASRSRRRLMIRLVKGAYWDSEIKRAQMEGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYHLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVGDGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADATLPLDELVADPVEAVEKLAQQEGQAGIPHPKIPLPRDLYGEGRINSAGLDL
                     ANEHRLASLSSALLSNAMQKWQAKPVLEQPVADGEMTPVINPAEPKDIVGWGREATES
                     EVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQMQQLIGLLVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTADARVRGVMFTGS
                     TEVATLLQRNIATRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAG
                     QRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRAKGRPVFQAARENSDDAQEWQTGTFVMPTLIELENFAELEKEVFGPVLHVVRYN
                     RNQLAELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLAHRPPNALNTTLTRQDARYPVDAQLKTTLLAPLTAL
                     TQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDEQDAL
                     TQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHGDS
                     DKLRTVCEAVAAREGAIVSVQGFARGESNMLLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            5718..7226
                     /gene="putP"
                     /locus_tag="OPY25_003514"
     CDS             5718..7226
                     /gene="putP"
                     /locus_tag="OPY25_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HCS0929030.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     FNNNALTLPDYFTGRFEDKSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATIIYTFIGGFLAVSWTDTVQASLMIFALILTPVMVIVGVGGFSESLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKSASQQELVWVGRVMVLVVALIAIALAAN
                     PDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYGWL
                     DLYEIIPGFIFGSLGIVIFSLLGKAPTATMQERFAKADAHYHSAPPSKLQAE"
     gene            8119..8907
                     /gene="phoH"
                     /locus_tag="OPY25_003515"
     CDS             8119..8907
                     /gene="phoH"
                     /locus_tag="OPY25_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HCS0929031.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEA
                     IGMARDSRDTSPVKARNEAQAHYLNAIDSKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVERIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLLKRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVRSGLSDALERFEEDEMVGIVHFNKDDCVRSALCQRTLHAYS"
     gene            complement(9013..9894)
                     /locus_tag="OPY25_003516"
     CDS             complement(9013..9894)
                     /locus_tag="OPY25_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCS0929032.1"
                     /translation="MEPQPPRLKPGKILDTLGAMQKSLTRASQRIAQYILAFPRQVTQ
                     SSIADLSRDTQAGEATVIRFCRTLGYKGFQDFKMDLAIELATTESDDSSPLLDAEVSE
                     SDDAHAIGLKLQNTISNVLSETLNLLDMQQVLGVVDALRHCHSVYIFGVGSSGITALD
                     MKHKLMRIGLRGDAVSNNHFMYMQATLLKAGDVAMGVSHSGTSPETVHSLRLARQAGA
                     TTVAITHNLGSPLCEEADFCLINGNRQGMLQGDSIGTKAAQLFVFDLLYTLLVQSSPE
                     QARESKLRTMNALDMTK"
     gene            complement(10180..11677)
                     /locus_tag="OPY25_003517"
                     /pseudo
     CDS             complement(10180..11677)
                     /locus_tag="OPY25_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
     gene            complement(12014..12694)
                     /locus_tag="OPY25_003518"
     CDS             complement(12014..12694)
                     /locus_tag="OPY25_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCS0929033.1"
                     /translation="MSLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAAS
                     AGAVAVRIEGIENLRTVRPHLSVPIIGIIKRDLTGSPVRITPYLQDVDALAQAGADII
                     AFDASFRSRPVDIDSLLTRIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGP
                     ITPVEPDLAMVTQLSHAGCRVIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQ
                     WFSHAVKR"
     gene            13201..>13677
                     /locus_tag="OPY25_003519"
     CDS             13201..>13677
                     /locus_tag="OPY25_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid mutarotase"
                     /protein_id="HCS0929034.1"
                     /translation="MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTG
                     AIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDKLYVFG
                     GVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGV"
BASE COUNT         3293 a         3425 c         3604 g         3355 t
ORIGIN      
        1 gcaggtcgta aaagtggtca gcacagcggg ggcaatttta agaatgaccc gcagcgtgca
       61 tccgaagcag gcaaaaaagg gggcaaaagc agtaaccgta atcgctagcc tgcgtcacaa
      121 cagcaagacg ctgagcgttt cgcgctaaaa agcgtcatgc gccaccgccg ccggatttcc
      181 ggcggttttt ttgtttataa gccggatttg gtatgcttgc gtcctgacga aaaggagagg
      241 gcgcatgtcg caacgcacag agaaaaaaat cgggaaacgt tcgcaggcca ccggtgcaaa
      301 acggcagctt atcttaaccg ccgcgcttgc cgttttttcc cagtatggca ttcatggcgc
      361 gcgtcttgaa caggtcgccg agcgggcagg cgtctccaaa accaatctgc tttattatta
      421 tccctcgaaa gaggcgctgt atgtcgcggt aatgcgacag attctggatg tctggttggc
      481 gccgctcaag gcgtttcgcg cagaattttc ccctctggag gccatcaaag agtatatccg
      541 tctcaagctg gaggtttcgc gtgattatcc gcaggcgtcg cggctcttct gcatggagat
      601 gctggcgggc gcgccgctct taatggatga actgaccggc gatctaaaag cgttgataga
      661 tgaaaaatcc gcgctgattg ccggatgggt gcacagcggg aaactcgcgc ccgtttctcc
      721 gcatcatttg atcttcatga tttgggccgc cacgcaacat tacgccgatt tcgcccctca
      781 ggttgaagcg gtaaccggcg cgacgcttcg cgatgaagcc tttttcaacc aaacggtcga
      841 aagcgttcag cgcattatta ttgaagggat tcgcgtgcgt taaccggctg gcggcagtgg
      901 gcagctcaaa tcaccctctt cacattgcag cagcgaggct aaaaacgctt cgcgttcgtt
      961 cgttttatcg gtcaggcact ggctggcgat catgggttga acgctgccgc cctccgtacc
     1021 tgagcgaatc agcgcgcaat cggcgtcgcg cagggcaatc catgccacct gcgctttttg
     1081 caatagctca cgctgcggcg gttgcgcacg cttaatcgcg ctttgatagg tttcgttcag
     1141 ctttttatct gccgcctggt attgcgcggc ggcgcagcga ttcatttcca gctgcgtact
     1201 ggcgctggca cactcatcgg ccaacgcctg actgctgaac aacaacgccg cgcaggtaag
     1261 gaaaattcgt ttcatacggt cctctgacgc gagtaaaaag gctccattga cggagcctta
     1321 attaaccaca gtattagcca attgtcatca ggctggcatt accgccagcg gcggcagtgt
     1381 ttacgctcag cgaacgttca atatagagcc gttccagcag catattgctt tcgccgcggg
     1441 cgaacccctg taccgacact atcgcgcctt cgcgggcggc gacggcttcg cacacggttc
     1501 gcagcttgtc ggagtcgccg tggaaaatca ccgcgtcaaa cggctgcgcc atcagcgttt
     1561 ccgctttcgc aaactggaca cgcgccgcga cggcggcggg gagacgtttc gccagatcgc
     1621 ggtggaaggc gtcgtctgac catagcgcct gactgccgac ggcgagaacg gcggcaagct
     1681 gcgtcaacgc gtcctgttca tcatcagcca ggcataacac ccgttcacgc ggcaacagcg
     1741 tccaggtatt acgctcgccg gtcggccccg gtagcaggcg ctgcgtgccg gcctgcgcca
     1801 gatcggcgaa ttgtcggcag agcgtctgta gcgccgggcg atccgccgcc cattgcgtca
     1861 gagcggtcaa cggcgcgagt agcgtggttt taagctgcgc atccaccggg taacgcgcat
     1921 cctgacgagt cagcgtcgta ttgagcgcat tgggcgggcg gtgtgccagc aggcggtaga
     1981 gatagagcgg ccctcccgct tttggcccgg tgccggacag gccttcgccg ccaaacggct
     2041 ggacgccgac gaccgcgccc accatattac ggttaacgta caggttgccg acatgggcgg
     2101 aaccggtgac ttgcgcaatg gtttcatcaa tacgggtatg tacgcccagc gttagcccgt
     2161 agccggaagc gttaatctgt tcgataagct ccgccagttg gttacggtta taacgcacga
     2221 cgtgcagcac gggcccgaag acctcttttt ccagttctgc gaagttttcc agctcaataa
     2281 gcgtgggcat aacaaacgta ccggtctgcc attcctgcgc gtcatcgctg ttttcacgcg
     2341 cggcctggaa aaccgggcgg cctttggcgc gcatcgtctg gatatgacgt tcaatgttgg
     2401 ctttggcctc gctatcgatc accggcccga tatcggtcgt cagacggcct ggattcccca
     2461 tccgacactc cgccatcgcg ccgcgtaaca ttttcagcgt atgttcggcg atatcgtcct
     2521 gcaaacacag cacgcggagc gcggaacagc gttgtccggc gctgtcgaag gcggaagcca
     2581 gcacatccac gaccacctgc tcggtgagcg cggaagagtc gacaatcata gcgttcatac
     2641 cgccggtttc cgcaatcaac ggaatagggc gcccctgggc gtcaagacgc gtggcgatgt
     2701 tgcgctgcaa caacgtcgcg acctccgtgg aaccggtaaa catcacgccg cgtacacgcg
     2761 catcggcggt aagctgggcg ccgacggttt ctccccgtcc cggcaacagt tgcacgacgc
     2821 ccggcggtac gcccgcttcc agcaaaatgg caatgccctg ggcggcaatc agcgatgtct
     2881 gctctgccgg tttcgccaga acgctgttac ctgccgccag cgcggcggcg atttggccag
     2941 tgaaaatggc cagcggaaag ttccacggac tgatacagac caccggccct aacgggcgat
     3001 gcgtttcgtt atcgaaatcg tcacgcactt gaccggcata ataatggagg aagtctaccg
     3061 cttcgcgcac ttcggcaatg gcgttgctga acgttttccc cgcttcacgc accaacaggc
     3121 caatcaactg ctgcatttgg tcttccatca ataccgccgc ccgctgcaaa atagcggcgc
     3181 gttcttgcgg cggcgtcgca aaccaaaccg gcgcctgatt gaccgcgttt tgcaacgcct
     3241 gttcaacctc gctttctgtc gcttcgcgtc cccagccaac aatatctttc ggttccgccg
     3301 ggttgataac cggcgtcatc tcaccgtcgg ccaccggttg ttccagcaca ggtttggcct
     3361 gccatttctg catggcgttg cttaacaggg cagaagaaag cgaggcgagg cgatgttcat
     3421 tcgctaaatc aagtccggcg gagtttatcc gaccttcgcc gtacagatcg cgcggcagcg
     3481 gaatttttgg atgcggtatg ccagcctgac cttcctgctg cgccagtttt tccacggcct
     3541 cgaccgggtc ggccaccagt tcatcgagcg gtagggtggc atcggcgatg cggttgacaa
     3601 aagaggtgtt ggcgccgttt tccagcaggc gtcgtaccag ataggccagc agggtttcgt
     3661 gtgttcccac cggcgcgtaa atacggcagg gacggttaag ttttccgtcc cccactttac
     3721 cggtgacctg ttcatacagc ggttctccca tgccgtgcag gcactggaat tcgtactgac
     3781 ccggatagta attttgcccg gccagatgat aaatcgccgc cagtgtgtga gcgttatggg
     3841 tcgcgaactg cgggtagatc agattaggga cggcgagcag ttttttcgcg caggccagat
     3901 aagagacatc ggtatacact ttgcgggtat aaactggata gccctccagc ccttccattt
     3961 gcgcgcgttt gatctcgcta tcccagtagg cgcctttcac cagacgaatc atcagccgac
     4021 ggcggctacg ggaggccaga tcgactaaat aatcaatgac cagcgggcag cgtttctggt
     4081 aagcctgaat cacaaagcca atgccgttcc agcccgccag ttcgggttcg aagcagagtt
     4141 tttccagcag atcaagcgag atctccagac gatccgcctc ttcggcgtcg atattgagac
     4201 cgatatcata ctggcgcgcc agcagcgtca gggatttcag gcgcggataa agctcctcca
     4261 ttacccgatc gtattgcgcg cgactatagc gtggatgcag ggcggacagc ttaatcgaga
     4321 tgcctggccc ttcgtaaata ccgcgaccgt tagacgcttt gccgatggca tgaatcgctt
     4381 gctggtaaga gaccatatag gcctgcgcat cggcggcggt taacgcggct tcgcccagca
     4441 tatcgtaaga atagcggaac cctttctctt ccagttttcg ggcattcgcc agcgcctgag
     4501 caatggtttc gccagtcacg aactgctcgc ccattaaacg catcgccatg tcgacgcctt
     4561 tgcggattaa cggttcgccg ctcttgccga taatgcggtt cagcgagcgc gaaagattgg
     4621 cttcgttatg cgttgagacc agtcggccgg taaagagcag cccccaggtg gcggcgttta
     4681 caaacagcga cgggctacgg ccaatatgcg actgccagtt gccattactg attttgtcgc
     4741 gaattaacgc atcgcgcgta gctttgtcgg gaatacgcag cagcgcttcc gccagacaca
     4801 tcagcgctac gccttcttgc gaagagaggg aaaactcctg caacaggcct tgcaccatac
     4861 ccgcgcgacc gctggcggat ttttgattgc gcaatttctc cgccagttga tacgccagtt
     4921 tatgcgcctg ctcagcgaca ggcggcgaca ggcgcgcctg ttccattagc attgacaccg
     4981 catcggtttc cgggcggcgc caggcggcgg tgatggcggc gcgagagacg gattggggaa
     5041 gaatctgttc ggcaaactcc agaaagggct gatgcggctc atcctgcggc gcgaccggct
     5101 cctcgctttc atttgccgcg ccggcaaaca gcgcaggtag ctccggtagc gtatcgctat
     5161 tttccagctt gtccagatag ctaaagattg cctgttttat taaccagtgc ggcgtgcgat
     5221 cgatacgcga cgcggccatt ttgatccgtt cgcgcgtggc gtcgtccagc ttaaccccca
     5281 tcgtggtggt tcccataccc tctactcctg ttattcgctc tatctgctaa ccaatagtta
     5341 gcggaaaata tccactatat tgcaactttg tgcaaccgcg ttaaatgtga cctgcgttgc
     5401 aagcttaaaa atgaataaat tgttaaaaaa agaaagtggg agtctgacgg ggaaaaccat
     5461 ctggatttat tttctctgcg gtagttaaca cttttaaaag gtgcaaccgc aaaaaatgtg
     5521 agagagtgca acctggagaa aaatagtatc cctctgcaat caaatttgat gtaaatggtg
     5581 tgttaaatcg attgtgaata accaccgatt ccggcaggat acggtcgccc tggtaaacat
     5641 aacacccttg ccacgttccg gcagggtaca aaacggcacg ctacggtagt gccaataaat
     5701 aaatttggag aaccttgatg gctattagca caccgatgtt ggtgacattc tgtgtctata
     5761 tttttggcat gatattgatt gggtttatcg cctggcgctc aaccaaaaac tttgatgact
     5821 atattcttgg cggtcgcagc ctggggccgt ttgttacggc tttatcagcc ggcgcgtcgg
     5881 atatgagcgg ctggctgtta atggggctgc ctggcgctat ctttctgtcg gggatctctg
     5941 aaagctggat cgccattggc ctgacgttag gcgcatggat taactggaag ctggtggccg
     6001 ggcgcctgcg cgtgcatacc gaatttaaca ataacgcgct cacgctgccg gactatttta
     6061 ccggtcggtt tgaggataag agccgagtcc tgcgtattat ttccgcgctg gtcattctgc
     6121 tgtttttcac tatctattgc gcatcaggta ttgtcgctgg ggcacgactg ttcgaaagca
     6181 ccttcggtat gagctatgaa accgcactgt gggcgggggc cgcggcaacc attatttata
     6241 cctttatcgg cgggtttctt gccgttagct ggacggatac cgttcaggcc agcctgatga
     6301 tttttgcgtt aatcctgacg ccggtgatgg ttattgtcgg cgtaggcggt tttagcgagt
     6361 cgctggaagt gatcaagcaa aagagcatcg agaatgtcga catgctcaag gggctgaatt
     6421 ttgtcgctat tatttctctg atgggctggg ggctgggtta cttcggtcag ccgcatatcc
     6481 tggcgcgctt tatggcggcg gattcccatc acagtattgt tcatgcgcgt cgtatcagta
     6541 tgacctggat gattctgtgt ctggcgggcg cggtggcggt gggcttcttt ggcattgcgt
     6601 actttaacaa taaccccgcg ctggccgggg cggtgaacca aaactcagaa cgcgtattta
     6661 ttgaactggc gcagatcctg tttaacccgt ggattgccgg tgttctgctg tctgctatcc
     6721 tggcggcggt gatgtcgacg ttgagctgtc agttgctggt atgctccagc gcgattacgg
     6781 aagatttata taaggctttt ctgcgtaaaa gcgccagcca gcaagagctg gtatgggtag
     6841 ggcgagtgat ggtgctggtg gtagcgctga tcgccattgc gctggcggcg aatcctgata
     6901 accgtgtgct ggggctggtg agctacgcct gggctggatt cggcgcggca tttggacctg
     6961 ttgtcctgtt ttctgtgatg tggtcgcgta tgacacgtaa cggcgcgctg gcgggaatga
     7021 ttattggcgc ggtgacggtt atcgtctgga aacaatatgg ctggctggat ctgtatgaga
     7081 ttatccctgg cttcattttc ggcagcctgg ggatcgtaat ctttagcctg cttggcaaag
     7141 cgccgacagc aacgatgcag gaacgctttg caaaagcgga cgcgcattat cattccgcgc
     7201 cgccgtcgaa gctacaggcg gaataaccga catgtccgat agcattattg ccatcggata
     7261 tattttacca ggcggcgtta tacgcctgcc tggtcctctg ataagtcccg gaccgattga
     7321 ctgaaggtgt tcaggtaaat gaggacgctc tctcaaacta tttttagccc ttgagcgccg
     7381 ttaacgcggc cgtaatacgt ctcgagtaat cactaactga ccatatatga aatcgcctgt
     7441 taatggtacc aatagccttg acgcaataga gtaatgacaa aaattaaaac gagtcagcgt
     7501 tactggcgta agtatgccgc acaaaatttt gcataaataa tgccgtttta gcgatgggag
     7561 agaggacacg ttaattactc cgttttaatc ttttatatgt tgaatattca atgggttatg
     7621 ggtgttttca ccattaatac ccatagtagc taatgattat cttttttagt ctcctgccaa
     7681 tgaaataatt gtgtaatctt tctgtaagag actgacaatg acgcaataat gtttggttaa
     7741 tgtttggtga atatattgtt gcattattga tgttttgtgt tgtacttagt agtaatagcg
     7801 gtagttcccc ggcagtgatg gtcactcact atggagatcg cgaatggtaa tgtccgcacc
     7861 aggacacatt gtttacagta gttacaacac cctgtacgga cattctctct ccggtggtgg
     7921 tcttgtcatc ttaaaagctc tcatcatttc ccttactgtc catacccatg acgccatatg
     7981 tggtgcgcgt agccgtgtgt ggcgtcgttt caaaaagcaa gctaaggctt acaaggaagc
     8041 caaccctcag atgtgtgtgc gcataatcgc gttcaagaga acgcgggtga tgtataccta
     8101 caactcaagg tgctatccat gggaagacaa aaagcagtga tcaaagctcg tcgtgaagca
     8161 aagcgtgtgt tgagacgaga ttcgcgtagt cataagcaac gtgaagaaga atcggtcacg
     8221 tcactggtac agatgggcgg agtagaagcc attggcatgg cgcgcgatag tcgcgatacc
     8281 tctcctgtta aggcgcgaaa tgaagcacag gcgcattatc tgaacgctat cgacagtaaa
     8341 cagcttattt ttgcgaccgg cgaagccggc tgcggaaaaa catggatcag tgcggcaaag
     8401 gcggcagaag cattgattca taaggacgtc gagaggatca ttgtgacgcg tccggtattg
     8461 caggctgatg aagatcttgg ttttttgccc ggtgatatcg ctgaaaaatt cgcgccttat
     8521 tttcgtcccg tctacgatgt cctgcttaaa cggttgggcg cgtcctttat gcaatattgt
     8581 ttgcgcccgg aaatcggtaa ggtagaaatt gccccgttcg cctatatgcg tgggcgtact
     8641 tttgaaaatg cggtcgtgat cctcgacgag gcgcaaaatg tgactgcggc gcaaatgaaa
     8701 atgtttttga cgcgattagg cgaaaatgtc acggtcattg tcaatggcga tattacgcaa
     8761 tgcgacctgc cgcgcggtgt gcgttccggg ttgagtgatg cgttggaacg ctttgaagaa
     8821 gatgaaatgg tggggattgt gcatttcaac aaagacgact gcgtgcgctc ggcgctttgt
     8881 cagcgaacgc tccacgcata cagctaatat agcattgact ttcagagccc gggagaccgg
     8941 gctttgttgt ctataaagcg tccagcagac tcatggacaa aaaaggaaaa tgacgcctgt
     9001 acgtgaaggg aattattttg tcatgtccag ggcattcatt gtccgtaatt tgctttctcg
     9061 ggcctgttcc ggcgaggact gtacaagaag ggtatagagc aggtcaaaga cgaaaagctg
     9121 cgcggctttc gtaccgatcg agtcaccctg caacattcct tgccgattac cattgatcag
     9181 gcaaaaatcg gcctcttcac ataatggaga acccagatta tgggtaatgg cgactgtggt
     9241 ggcgccagcc tgtcgggcca atcggagtga atgcactgtt tctggcgatg tgcccgagtg
     9301 actgacaccc atcgcgacat cgcctgcttt taatagcgta gcctgcatgt acataaaatg
     9361 gttattgctt accgcatcgc cccgtaaacc aatacgcatt agcttgtgtt tcatatccag
     9421 cgccgtgatc cccgatgagc ccacaccaaa gatataaact gagtgacagt gacgtagggc
     9481 gtccacgaca ccgagaacct gttgcatatc aagcagattt agcgtttcag ataatacatt
     9541 actaatggtg ttctgcaatt ttaaaccaat ggcgtgggca tcgtcggatt cgctaacttc
     9601 ggcatccagt agaggactac tgtcatcaga ctcggtagtg gcaagttcaa tggccaggtc
     9661 cattttaaaa tcctgaaaac ctttatagcc cagggtgcga caaaagcgaa taaccgtggc
     9721 ttctccggcc tgtgtgtcgc gcgacaaatc ggcaatagat gactgtgtca cctgtctggg
     9781 gaaggctaaa atatattgcg caatacgctg ggaggcacgt gtcaggcttt tttgcatagc
     9841 acccagagtg tcaaggattt ttccgggttt aagacgtggg ggttgaggct ccatatagtt
     9901 cctgctcttg agggctgatt gcggcacaaa gcctgcaata tcgaacagag cagagcctat
     9961 caagtctgcg gcatgaaaaa aagcgcgatg taagtaaagg agggggaata tttacatcgc
    10021 gttgccaact tatgacagaa catcactgga gagtaatctg tttgctctta cggtgtttat
    10081 agcgcgccat ctgtcggatg gtttatatct ggcccggtat tgtcgccccg cgcgttggcg
    10141 tcaccgtgtg ctgtgtcggt atagcgtggt atcatgaaat cataatgtca cctttggttc
    10201 aggtttttca tccagcgtca atggcggtgc cggggcaaat aacggggcga aaataacgcc
    10261 gctgatcacc acgcttagcg agccaatgac cccataaaag aagaagttaa ggtcagtggc
    10321 atagcgtgtg cccagcacgg taatgacgct gataataatt cctaaaaccg cactcccggc
    10381 atttgctcgt ttaaagaaaa tgcccagcat gaacagaccg gtcattggcc ctcccatcag
    10441 acctatcaga ctattaaatg catcccagat ttctgattca tcggccatga ccagccatac
    10501 cgaggccgcg ctacttatca ggcccgcgac cagaataact aacttagcta ttttcatacg
    10561 gttttctggc gttccttttt tatgactcaa acgctgatag atatcggaat taaaacaact
    10621 ggaaatgctg tttaagctgc tggagatgct ggactgcgcg gcagcgaaaa tagcggagat
    10681 tatcaaccct gcaatgccga ctggcatttc ggtgaccacg aataagggca aaatgccgcc
    10741 agtgttgaat cccgccggta ataattgtgg atgttgctga tagtagacaa ataatgccga
    10801 gccgatagca aaaaagaaaa cagggatcac agcaaccagt ttggcatttg taagtaatgt
    10861 tttcttcgtt tcctctatgg agtcagtcac gatatagcgt tggaccacat cctgactggc
    10921 agtaaattgc tgaatattgg caaacagaaa accaatcatc aatacaggta ctgtgctttc
    10981 cgtccagctc cagtggaact gcgtagccgg aaagaattta tccgcctgct gcgtcaccgt
    11041 aaaaatttca ccaatgccgc cctggacttt gagacatatc actataaaaa tcagtatcgc
    11101 gctgccagaa agtaagagac cttgaataac atcagtccat attactcctt caattccccc
    11161 ccatccaggt ataaatgata cacatcacac taatcaacag taccaaaatc accgggtcta
    11221 tagcgatgaa ggggcgcaag gccagcacgg tgaggaaagt gataatggcg atacgtccaa
    11281 tatgaaacaa cataaatgac atgctggcga acagacggca gcgcacatcg aaccgtgctt
    11341 cgagatattc ataggctgat gtgactttca atttccgaaa aaacggaata tagaaataaa
    11401 aaaccagcgg taaaattgcg atagccagat actgaccaat gataaacgtc cagtcggaag
    11461 taaacgcttt ggcaggaatt gacataaatg taattgagct taacgtagta gcaaatacac
    11521 tgaccccagc cgcccaacca ggaacccggc caccaccgcg aaaataatcg tctgctgttt
    11581 tttgccgtct ggaaaaatag acaccgacta acatcatggc caggaggtag ccaaataata
    11641 caaaataatt aacgatgccg aaagaatgtg taatcatagt tctttcctgc ttatggtttt
    11701 gagtagcgtt gcggtcatcg tctgtgtatt tttatcttcc catcattcag acgatacgat
    11761 attcagatca agcaatagtt tttgttaatc tcaatgacgc taatcatgag atgtaaaagg
    11821 cagagcattt atgctccacc aatggtgatg cccagacgta tgtcctgccg gatacctgaa
    11881 atagcagcta tccgatattg cgttcaaaca ggcttcaggc ctgggtatcg tatttgccga
    11941 tagcattctt aacgtcggat tattctctga gacataaata tcaatagtaa gcgtgttcat
    12001 tttcttttcc tgttcagcgt tttactgcgt gactgaacca ctgacagata tgctcgatac
    12061 gggtgatagc ggaaccaacg gtaactgccc aggcaccatg ctcaatagca ttggccgcca
    12121 gtgcaggcgt gttatagcgc ccctcggcaa taacacgaca acctgcatga ctcagttgtg
    12181 tcaccattgc caaatctggc tcaaccggcg tgatgggacc ggtatagcca gacagtgttg
    12241 taccaatgaa ttcgattcct ttctgatggc aacttatgcc ttcattcacg gttgaacagt
    12301 ctgccatcgc cagtaatcca tgcaggcgaa tacgtgtcag taaactatca atatcaaccg
    12361 ggcgagagcg gaatgaggca tcaaaagcga taatatcggc acctgcctgc gccagggcgt
    12421 caacatcctg taaatatgga gtgatacgga ctggcgaccc tgtaaggtca cgtttaatta
    12481 tcccaataat aggaacagaa agatggggac gaacagtccg cagattctca atgccttcaa
    12541 tgcgcacagc gaccgcaccc gccgaagccg ctgcctgtgc cattgcagcc acaatttcag
    12601 gtttatccat agggctgcct ggtaccggtt ggcatgagac aatcagccca ccgttttcgt
    12661 gtacactttg ttccagcctg gctaatagtg acatccagtt ccgccttata tattttgaag
    12721 ttttactccg ttttatatta tgttgtggag tgttgctgca tcaagcaaaa agatagaaaa
    12781 atgtgaacac agtcataagg tatgtttgtc attcaattac tgcgccagcg gatttgaggc
    12841 tataacctga agctacaaga caaatacaat tcattctgac ggcagcatgc tgtattttat
    12901 taactgcttc cggcataaag ataaaatgct cagaaggagc ttatacgcca cgggatagcc
    12961 agtatgaaat gcatcacata attcttgttg tatttattca gaatgcaatc actaatgagt
    13021 ttgcccataa caggtcaccc ataatcactt ctaacatcac catagtgtgc ttttacctcg
    13081 cacatggtaa ccccatgtaa ttatttttag cgcttggtca cattttgtca ttttcattgt
    13141 tgaaattatg caccataaga tcactaatga tgaagcttta ctccagttgt atttcttcgc
    13201 atggggatgc agatgaaaaa ttttaagaaa atgatgacgc taatggcgct atgtttatca
    13261 gttgctatca ccacatcagg atatgcaacc acgcttcctg atataccaga accactgaaa
    13321 aatggtactg gcgctattga taataatggc gtgatttatg tcggcttagg taccgcaggg
    13381 acatcctggt ataaaattga tcttaaaaag caacataaag actgggagcg tataaagtcg
    13441 tttcctggtg gagctcgtga gcaatccgtg tcggtatttt taaatgataa gctgtatgtt
    13501 tttggtggcg tagggaaaaa aaacagtgaa tcaccgttgc aggtttatag cgatgtgtac
    13561 aaatactcac cggtgaaaaa tacatggcaa aaagttgata ctatatctcc agttggatta
    13621 acagggcata cgggagtaaa attaaacgaa acgatggtac ttattaccgg aggggtt
//
LOCUS       DAJVKX010000120        13523 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.120, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000120 DAJVKX010000000
VERSION     DAJVKX010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13523
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.120"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(5..1405)
                     /locus_tag="OPY25_003520"
     CDS             complement(5..1405)
                     /locus_tag="OPY25_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c peroxidase"
                     /protein_id="HCS0929035.1"
                     /translation="MKKITLYATTVITVGLLCYLGLSGYVWYYDKQRSKKSDVQASVV
                     GENNKILGYFREKGCDYCHTPSAELPFYSSFPVAKQLMDYDIQLGYKSFNLEAVRAAL
                     IADTPVPQSELNKIEWVMQHQTMPPTRYVALHWAGGVSDKERTDILNWIADQRERNYA
                     SADTDPAHRNEPVQPIPRNIPVDAKKVDLGFRLYHDERLSGDSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNIEQFWDGRAATLQEQAGGPPLNPIEMASKSW
                     DEIISKLDKDPVLKKDFQAVYPQGFTGENITDAIAEFEKTLITPDSAFDKWLRGDENA
                     LTAQQKHGYQLFKENKCATCHGGIILGGRSFEPLGLKRDFNFGEITAADIGRMNVTKE
                     VRDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGTDLPQNDIDDIVAFL
                     ESLTGVYTPYQPEYAQ"
     gene            complement(1595..2227)
                     /gene="torD"
                     /locus_tag="OPY25_003521"
     CDS             complement(1595..2227)
                     /gene="torD"
                     /locus_tag="OPY25_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HCS0929036.1"
                     /translation="MIKQPALAQEQYACVYAWLALLFFREVDDEGLIQLQSAEIADWL
                     ALLKRQPALAASVALLEQKIAALSLRQDAQLELAADFCGLFLMTDKKSALPYASQYPQ
                     QEPGMIKHLLLEAGMEVNDDFKEPADHLAIYLELLSHLHFSLGESFQQRRMNKLRQKT
                     LSSLLEWLPEFTNNCLKHDPYGFYAALSQLLLAIVRFDDGKEDLSIVAVE"
     gene            complement(2220..4772)
                     /gene="torA"
                     /locus_tag="OPY25_003522"
     CDS             complement(2220..4772)
                     /gene="torA"
                     /locus_tag="OPY25_003522"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HCS0929037.1"
                     /translation="MKNKDSLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAVA
                     PGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
                     QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDMVKNQQANWWCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTH
                     DYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYCVGFDQFLPYLLGEK
                     DGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIP
                     IARFMDAILEPGKIINWNGKSVKLPPLKMCVFAGTNPFHRHQQINRIIEGWRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEARNDFDI
                     FRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGG
                     PGSQRWPLHLQSVHPDFRLHSQLCESETLRQQYAVGGKEPVFINPQDASARGIRNGDI
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDLNALCKYGNPNVLTLDTG
                     TSQLAQATSAHTTLVEIEKYTGPMDNVTAFNGPAEMVAQCEYVPASQGNPHD"
     gene            complement(4762..5946)
                     /gene="torC"
                     /locus_tag="OPY25_003523"
     CDS             complement(4762..5946)
                     /gene="torC"
                     /locus_tag="OPY25_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HCS0929038.1"
                     /translation="MRKLWRALLRPSTRWSILALVIVGIVIGVALIVLPHVGIKLTST
                     TEFCVSCHSVQPVYQEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDLYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQNPEAARQM
                     KIAAKENQSCIDCHKGIAHQLPDMSSGFRKQFDELRASASTHNDGDTLYSLDIKPIYA
                     AKGDKEPAGSLLPASEVKVLKRDGDWLQVQIEGWTETDGRQRVLTQLPGKRIFVASIR
                     GDVQQHVKTLEETTVAATNTQWSKLQATAWMQKGDMVNDIKPIWAYADSLYNGTCNQC
                     HGAPDKAHFDANGWIGTLNGMIGFTSLDKRDERTLLKYLQMNASDTTNTPHSDKGEHN
                     EK"
     gene            6076..6770
                     /gene="torR"
                     /locus_tag="OPY25_003524"
                     /pseudo
     CDS             6076..6770
                     /gene="torR"
                     /locus_tag="OPY25_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462724.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
     gene            complement(6743..7783)
                     /gene="torT"
                     /locus_tag="OPY25_003525"
     CDS             complement(6743..7783)
                     /gene="torT"
                     /locus_tag="OPY25_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HCS0929039.1"
                     /translation="MRTLISFFFLIIIVSNVETASAETGLLHWTRADRAIPWRQTSVN
                     ASKPWKLCALYPSLKDSYWLSVNYGMQKAAKLYGVDLKVLEANGYRQLATQQQQMTQC
                     REWGADAILLGSSTDRFPELERYAGNVPVIELVNMIHDASVATRIGLPWFQMGYLPGR
                     FLVQWSKGKTLNVLLFPGPEEAGGSQEMVAGFRQAIKGSAINIVDIAWGDNDIEVQRN
                     LLQEMLERHPDANVVAGSAIAAEAAMGEGRNLTTPLTIVSFYLTHQVYRGLKRGHILM
                     ALSDQMAWQGELAITQSIKVLQGQPVPENISPPVLILTHNNADSARVRRSLSPPGFRP
                     VYLYQYTSEAKK"
     gene            7863..10598
                     /gene="torS"
                     /locus_tag="OPY25_003526"
     CDS             7863..10598
                     /gene="torS"
                     /locus_tag="OPY25_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HCS0929040.1"
                     /translation="MSTPSLTHRLWLAFALMAALTLLSTVIGWISLRVISQVEQTNTQ
                     ALLPTMNMARQLSEASAYELFSAQNLTNADSEGVWLAQGKMLKAQSLKINHLLQALSE
                     QGFNTSAIARQEKEIAQTLGQQGTLVGEILTLRAQQQQLSRQIAEAAESIAAQAHGQA
                     NNAATSAGATQAGIYDLIESGKGDQAERALDRLIDIDLEYVNQMNELRVNALRFKQLI
                     VTLKDAQGLSDAEETDEKLNQLVKILSRRQQRIEDPTVRAQIADALGKINQYTTLVTL
                     FRKENAIRDQLQTLMANNLFQFTRFSTEVSQLVNAIEKRNEAGLARLTHASQRGQIGL
                     VILGILALCSLSFILWRVVYRSVSRPLAQQTQALQRLLEGDIDSPFPEAAGVSELDTI
                     SRLMEAFRANVRKLNRHREDLAEQVRSQTAELHALVLEHRQARAEAEKANEAKSTFLA
                     AMSHEIRTPLYGILGTVQLLADKPLMANYRDDLQAINDSGESLLAILNDILDYSAIEV
                     GGTNVSISEEPFEPRQLLNSALHLMHSRVQVALITDFSEQLPSTLQGDPRRIRQIVIN
                     LLSNAAKFTDRGSIVLRTFCDDQSWFIEVEDTGCGIPEAKLTAIFKPFVQATGCRGGT
                     GLGLAISASLAEAMGGTLTVTSTLHVGSCFRLQLPVRHPKPASKSAFREPVNLNGLRL
                     LLIEDNMLTQRITAEMLTGKGVKVSVAESANDALRCLAEGEPFDVALVDFDLPDYDGL
                     TLAQQLMSLYPAMKRIGFSAHVIDDNLRQRTAGLFCGIIQKPVPREELYRMIAHYLQG
                     KSHNARVMLNEHQLAGDMASVGPEKLRQWVALFKDSALPLVEEIEAARAMNDDVNIKR
                     LAHKLKSGCASLGMTQATEACRELELQPLSDIDIKTIVTQGVTALDAWIAGHPSP"
     gene            complement(10703..11830)
                     /locus_tag="OPY25_003527"
     CDS             complement(10703..11830)
                     /locus_tag="OPY25_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006762570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4056 domain-containing protein"
                     /protein_id="HCS0929041.1"
                     /translation="MRTIVRVIFLALLFLAGSARAALPLTLYLSTLPMPAASEAWPTM
                     PPQPLPKGLRPCCAFGYDLHAELLGLPVPFYQLNNVVTVDSLGHHQYNDHLYSGVANL
                     IGLSGENNGIVYTLRGGFIDTAHVRDTADMTVYIFSQLLPKLGQAFTLNLGEELAERR
                     LVFTAFTPPVDARERYTLAAWLSAHLAFQVAEWHEIAQWYGFESVRGFSEGVSAFSPE
                     DLYSNLAGARLAASLIVDGQTKTQEMYNTAMETALRQALTQLAAQPAQITRFQFDMLD
                     GRWWNSQRRVPEKYLVLHRNYQMGDDRLPTAVPGEITSLLPLSLPHRWRGIQLSTLAQ
                     LQLWPSEDMAQLPPPAHYYSEKDFAALAEQARLQDEKTQNH"
     gene            complement(11827..12966)
                     /locus_tag="OPY25_003528"
     CDS             complement(11827..12966)
                     /locus_tag="OPY25_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BamA/TamA family outer membrane protein"
                     /protein_id="HCS0929042.1"
                     /translation="MNRCHCRQLLCVAGVLSGVAQAALPSRSQVDGWLQQMGDSDTYD
                     AAKGVNWGVMPGPFYTPELGLGIGTAIVGMYRPDPADKVSQISTLSLSGYFSSTGAFG
                     VSLQNYAFFAQDRWRFFLTGALSDTPTYYWGQGFAAGDKDSHKQAYTAQVLDLQPMLY
                     RRLVNNIYLGVGWTLDVQHAAQINEDDPPRIQHTAQGGSSLSNGGSVEISWDDRDFMP
                     NPRKGQYATLRYTHFAPDIGSDTRFDEYQLHYSQYHAVDDKDVLAWEADGAFTQGYVP
                     WNMLPLLGSNHRMRGYYEGRYRDKNAVSGQLEYRHKLSWRHGVVGWVGAGTMGSSLHH
                     LDDGRWLPSAGVGYRFEFKPRVNVRLDYGVGKGSSGFYFQVGEAF"
     gene            complement(12963..>13523)
                     /locus_tag="OPY25_003529"
     CDS             complement(12963..>13523)
                     /locus_tag="OPY25_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016162021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929043.1"
                     /translation="VSQIGVGLMTKNGHVFHPADLQNLKFKLDFKGTTYGIGTTLVGG
                     VGNWFTAVDANYTQTQFDILDGSIDAFTVSPRVGYRFTTPGIDKMHLPSGKLNVWVGS
                     MYQDVQQEFKGSLDDLTMPSATLQRLVSMANYNNNGRFDVKQHLQSPWNMLLGAQYEI
                     TRHFNVTTEFGFAERNSFFVAGEYRF"
BASE COUNT         3127 a         3723 c         3546 g         3127 t
ORIGIN      
        1 attgtcattg cgcatattca ggttgatatg gcgtataaac accggtcagg ctttccagga
       61 aggcgacgat atcgtcaata tcgttttgcg gcagatcggt gccaacctgg taacgcagca
      121 tcagttttac cgcgccatcc agcgtcggta cgtcgccccg atggaaataa ggcgctgtta
      181 acgcgacgtt gcgtaagcct gggacttttt gccgtaattt atcgcgaacc tctttggtga
      241 cgttcatacg accaatatcc gctgcggtaa tttcgccaaa attaaagtct cgctttaatc
      301 ccaatggttc aaaagagcgc ccgcctaaaa tgataccgcc gtgacaggtt gcacatttat
      361 tttctttaaa taattgataa ccgtgtttct gttgcgcggt cagcgcattt tcatctccac
      421 gtagccattt atcaaaagcg gaatccggcg ttatcaacgt tttttcgaat tcggcgatcg
      481 catcagtaat attttccccg gtaaatcctt gcggataaac cgcctggaaa tcttttttca
      541 ggacagggtc tttatcaagc ttgctaataa tttcatccca ggatttagag gccatttcaa
      601 taggatttaa cggcggtccg cctgcttgct cctgcagggt tgcagcacga ccatcccaaa
      661 attgttcgat attaaatacg gagttgaata ccgtcggcgc atttattggc cctaccgcac
      721 cgccaacgcc aattgaggtt tttctgccat cgacaccgcc cgcatttaac gcgtgacaat
      781 gcgcacagga tattgtgctg tcgccggata aacgttcatc atgataaagt cggaaaccta
      841 agtcgacttt tttcgcatcg acgggaatat tgcgcggaat aggctgaacg ggttcattcc
      901 ggtgtgcggg gtcggtatcg gcgctggcat agttgcgctc acgctgatcg gctatccagt
      961 tcaggatgtc agtacgctct ttatcgctga cgccccccgc ccagtgcagc gcgacatagc
     1021 gggttggtgg catagtctga tgttgcataa cccattcaat tttattcagt tcgctttgcg
     1081 gcaccggcgt atccgcaatc agggcggccc gtaccgcctc caggttaaac gacttgtagc
     1141 cgagctggat atcgtaatcc attagctgct ttgccaccgg aaaagaggaa taaaaaggca
     1201 attcagcgga aggcgtatga caataatcac atcctttctc cctgaaataa cccagtattt
     1261 tattattttc acccacaacc gaggcctgca catcgctttt tttactgcgc tgtttgtcgt
     1321 aataccatac atacccggac aaacctaaat aacataacag cccaacggtg ataaccgttg
     1381 tcgcatagag ggtaattttt ttcatatcac tatccttatg gggtattgcg gcataattaa
     1441 ttaaatttta tttttttact catgaggccc gtcaatacta aatacaaacc catcatggat
     1501 attgattggt atcaataatt acaattggct aaacctatag atatgataac ccccgactat
     1561 cgtaagattt attttgcgat gcccgtcaca gggtttattc aaccgcaaca atggataaat
     1621 cctcttttcc gtcatcaaaa cgaacgatag ccaacaataa ttgacttaac gcagcataaa
     1681 aaccataggg atcatgctta aggcaattat ttgtaaattc cggaagccac tccagtaatg
     1741 acgataatgt tttctggcgt aatttattca ttctccgttg ttggaacgat tcacccaatg
     1801 aaaaatgtaa atggctgagt aattccagat aaatcgccaa gtggtcggcc ggctctttaa
     1861 aatcgtcgtt gacttccatc ccggcttcaa gcaataaatg tttaatcatg ccgggttcct
     1921 gctgcgggta ttgcgaggcg tagggcaagg ccgatttttt atccgtcatc aggaacaatc
     1981 cgcaaaaatc cgcggccagc tccagctgcg catcctgacg caggctaagc gcggcaattt
     2041 tttgttcgag taacgccacc gacgccgcca gcgctggctg acgctttaac agcgccagcc
     2101 agtccgcgat ttccgcggac tgtaattgta ttaacccttc atcatccact tcccggaaaa
     2161 agagtaacgc cagccatgca tatacgcagg cgtactgttc ctgagcaagc gctggctgct
     2221 taatcatgcg gattcccctg cgatgcgggt acatattcac actgcgcgac catctcggcc
     2281 ggaccgttaa acgccgtgac gttatccata ggaccggtat atttttcaat ttccaccagc
     2341 gtcgtatgcg cgctggtcgc ctgcgcgagc tgtgatgtac cggtatccag cgttaatacg
     2401 ttagggttgc cgtacttaca taacgcgttg agatcgccgc ctttatcagg atcgtaccag
     2461 gcaccttcat gaattcgcgc cacgcccggc gcatagcgat cggaaactac cgctcccgcc
     2521 agtacctgcc cgcgtgcatt gaatacccgc acgatgtcac cgttgcggat cccgcgcgcg
     2581 ctggcatcct gtgggttaat aaagaccggc tccttgccgc caacggcata ttgctgacgc
     2641 agcgtttccg actcgcacag ttgggaatgc agacggaaat cagggtggac ggactgtaag
     2701 tgcagcggcc agcgctgcga tcccggcccg ccatgcgagc gttcgatttt ttcgaaccac
     2761 atgggatggc cctgacaatc gtcgtattgc atgtcggcga tcgttttgga gtaaatctcg
     2821 atcaaaccgc ttggcgtgcc caacggctcc aggtccggat cttcacggaa agcctgatgg
     2881 cgcacaaaca tctgcggatg atcaaactcg atgtactcct gttgattcca gaacacctcg
     2941 aaagtcggta agtggatacc gcgacctttt ccctgctggc tcccttcctg ccagatgcgt
     3001 ttcagccagc ccatttcatc aagaccttcc gtgaatgccg cttcacggtt aaagcgtcgg
     3061 cagagatcgc ggaaaatatc aaagtcgtta cgcgcttcaa actgcggcga caccacctgt
     3121 ttcatggcga taatgccgcg gttagagtgg ttgccgaact gatcgaggtc gttacgctca
     3181 aattgggtgg tagccggcaa aacgatatcc gcaaagcggc aggtcgacgt ccactggtta
     3241 tcaatagcga tgaccgtttc cagcttgcgc cagccttcaa ttatgcggtt aatttgttgg
     3301 tgtcggtgga acgggttggt cccggcgaac acgcacatct tcagcggcgg taatttaacc
     3361 gatttcccgt tccagttaat gatcttgccc ggttcaagaa tggcatccat aaaacgcgca
     3421 ataggaatgg tgctgctgta gcctttgtaa tccgtgctgt cgtgcactgg cggaacggtc
     3481 gtcgaaccgg aaaagccgct taaaatgatc cctttacgac caggcgtccc ggcgccgtta
     3541 tagtgccagc caaaaccaaa gccgccgccc ggtaaaccaa tctgtcccag cattgccgcc
     3601 agcacgacga ccatccatga ccactgttcg ccatgctgca tacgttgtac gcaccagcca
     3661 gcgatgattt gcgttctgtc gcccgccatc tgccgcgcca acgcgcggat ggtgtcggcg
     3721 tcaataccgc acagtttttc cgcccaggcg gcatctttgg gctgtccatc tttctcgccc
     3781 agcaaatagg ggaggaactg gtcaaaaccg acgcagtagt tatcgaggaa atttttatcg
     3841 tacagtttct cgctgtacag ggtatgcgcc agcgccagtt gtaacgggac atccgtctgc
     3901 gggttaatgg cgatatgttt gaccttatcg cgccccagat aatcgtgcgt ggaggtgacg
     3961 accgggtcga tgctgatgac cgagatagcg ccgctggcaa ccttctcttt taattgttca
     4021 tagtactgat agacatcgtg atccgggcac caccagtttg cctgctggtt tttcaccata
     4081 tcagaacccc atagcacaat cgttttactg ttctgtaaaa ccagaggcca tgacgtttgc
     4141 tgctcgtaca cttccattga acccaccaca cgcggcagaa tcacctgcgc cgcgccggtc
     4201 gaatagtccc ctcccgtgct gacgctattg ccatgtagcg caatcgcgcg cgccagcatc
     4261 ccggaggcgt tatggaacat gccggtagat tgccaaccgc tcgccgtcag taacgcgctc
     4321 ggcccgtagg ttttttgcac ccgctccagt tcctgataga acagatccag cgcttcatcc
     4381 caggagacgc gcacaaaacg attatcgccg cgctgcgagg tgtcgctttg atgacctttg
     4441 cgcatccagt cgacgcgcac catcggatag cgaatacgcg ccgcgttgtg gacgtgatcg
     4501 ggcagaccgg cgatcatttt ggacgggtat ttatcctgtt caaacggttt tgccgccaca
     4561 aatcgaccgt caaccaccgt ggcgcgaatc gccccccagt gagaaccggt aaggataccc
     4621 tctttcgtcg cggcgcctgg cgcaacggca tccgctgcgc gggcgctacg gggcgtcagt
     4681 agtgacggcc ccagcattcc tgccaccgtc aagccgccaa gctgcgccag aaaacgtcga
     4741 cgagagacgt gtaacgagtc cttatttttc attgtgttct cccttatcgc tgtgcggcgt
     4801 gttggtggta tcagacgcat tcatctggag atatttcaac aaggtacgtt catcacgctt
     4861 atccagactg gtgaaaccga tcatgccgtt gagcgtgccg atccagccgt tagcgtcaaa
     4921 gtgcgctttg tccggcgcac cgtgacactg attacaggtg ccgttataga gggagtcggc
     4981 ataggcccaa atcggtttaa tgtcatttac catgtcacct ttttgcatcc acgcggttgc
     5041 ctgtaatttg ctccactgag tattggtcgc cgcgacggtg gtctcttcca gcgttttcac
     5101 atgctgttgc acatcgccgc gaatcgaggc gacaaaaata cgtttaccgg gcaactgcgt
     5161 cagcacgcgc tggcgaccgt ccgtctccgt ccagccttcg atttgcactt gcagccagtc
     5221 accgtcccgt ttaaggactt tcacttcaga agcaggcaac agcgaacctg ccggttcttt
     5281 atcgccttta gcggcgtaaa tcggcttgat atccagcgaa tagagcgtat cgccgtcatt
     5341 atgcgtactg gcgctggcgc gcagttcatc aaactgtttg cggaaaccgc tgctcatatc
     5401 cggtagctgg tgggcaatcc ctttatggca gtcgatgcag gattgatttt ctttcgcggc
     5461 gattttcatt tgccgcgccg cttccgggtt ctgtttcgcg tgatccatcg catcgtagtt
     5521 atggcaggaa cgacaggtcg cggagttatt ctctttcatg cgcgcccatt ctcgctcggc
     5581 aagctcggcg cgtttagctt caaatttttc cggggtatca atcgagtggg cgataaatgt
     5641 ctggtaaaga tcgttgctgg cttccagctt acgtttcacc atgcctggaa tatcgggggg
     5701 gatatggcaa tcgtggcatt ccgcgcgtac gccggaagcg ttctggaaat gtacggactg
     5761 tttatattcc tgatacaccg gctgcacact atggcagctg acgcaaaact ctgtcgtact
     5821 ggtcagtttg ataccgacgt gaggtaacac gatcagcgca acgccgatca caatcccgac
     5881 aatgaccagc gccagtatcg accaacgggt gcttggcctg agtaacgctc tccagagttt
     5941 tcgcataata gcccctgtaa ttatatggtt taatgcgcag atcttattcc gcaaatatga
     6001 acagcgtcac tggtcaggat gaacgggata cggcaatata tgaacagata tgaacagaaa
     6061 gagaccgcgc gcaggatgtc acatcacatt gttattgttg aggatgaacc tgttactcag
     6121 gccaggttac aggcctattt tgagcaggag gggtatcgcg tttcggtgac cgacagcggc
     6181 gcgggcctgc gcgtgacatc atggagcatg agcacgtttc gctgatcctg ctggatatca
     6241 acctccccga tgaaaacggg ttgatgctga ccagggcgct acgcgaacgc tccacggtgg
     6301 gcattattct ggtgacgggg cgttgcgacc aaatcgaccg catcgtcggg ctggagatgg
     6361 gcgcggacga ctacgtcacc aagccgctgg aactgcgcga gctggtagtg cgggtgaaaa
     6421 atcttttgtg gcgtatcgat ctggcccgcc ccacgccgca aaatgccagt gaaaactgct
     6481 atatgttttc cggctactgc ctgaacgtga tgaatcacac gctggagcac aacggtgaag
     6541 ccattaagct tacgcgcgcg gagtacgagc tgctgctggc ctttgtgacc aacccaggca
     6601 aagtgctgca tcgcgaacgt ctgctgcgaa tgctttccgc ccgccgcgta gagaccccgg
     6661 atctccgcac gattgatgtc ctggttcgcc gcttacgtca taaaattacg ccggaactgc
     6721 tggtcacaca gcatggcgaa ggctactttt tagcctcgga ggtgtattga tacagataga
     6781 cgggccgaaa tcccggaggc gatagcgaac ggcgaacgcg cgcgctgtcg gcgttgttat
     6841 gcgtcaaaat aagtaccggc gggctgatat tttcaggcac cggttgcccc tgtaagacct
     6901 taatcgactg cgttatcgct aattctccct gccaggccat ctgatcgctg agcgccatca
     6961 ggatatggcc gcgttttaaa ccgcgataaa cttgatgcgt cagataaaat gagacgatcg
     7021 tgagcggagt cgtcaaattt cgcccttcgc ccatcgccgc ctccgccgct atcgccgacc
     7081 cggcgaccac attggcgtcc ggatggcgtt ccagcatttc ctggagtaag tttcgctgca
     7141 cttcaatgtc gttatcgccc caggcgatat ccacaatgtt gatggcgctg cctttaattg
     7201 cctgacgaaa acccgccacc atctcctgac tgccgccggc ttcttccggc cccgggaaga
     7261 gtaaaacgtt aagcgttttt cctttgctcc actgcaccag gaaacgtccc ggcagataac
     7321 ccatctgaaa ccacggcaga ccaatgcggg ttgcgacgct ggcatcgtga atcatgttca
     7381 ccagttcaat aaccggcaca ttaccggcat atcgttccag ctccgggaaa cgatcggtac
     7441 tgctgccaag cagaatagcg tcggcgcccc actcccggca ctgcgtcatt tgctgttgtt
     7501 gcgtcgccag ttgccgatag ccattcgctt ccagcacttt taaatcaacg ccatacaatt
     7561 tggccgcttt ttgcatcccg tagttgacgg acaaccagta agaatctttc aggctggggt
     7621 ataatgcgca cagtttccag ggtttactcg cattgactga cgtttgccgc cagggaatcg
     7681 cccgatcggc gcgcgtccag tgtagcaacc cggtttcggc tgacgccgtt tctacattcg
     7741 agacgatgat tatcaaaaaa aagaacgaaa taagcgtgcg catgatagcc ccaccagcaa
     7801 caaggtttta tcctaatggt ttttccggcg gcaactcaac ccatttcacc cgcggcgcat
     7861 aaatgtcaac gccttcactg acccacagat tatggctggc cttcgctctg atggcggcac
     7921 tcaccctgct cagcaccgtg atcggctgga taagcctgcg cgtcattagt caggtggagc
     7981 aaaccaatac gcaagcgctg ctccccacga tgaatatggc caggcagtta agcgaagcca
     8041 gcgcttacga gctcttttcc gcgcaaaatc tgaccaatgc cgacagcgag ggcgtttggc
     8101 tggcgcaggg gaagatgctg aaagcgcaaa gccttaaaat taaccatctt ttgcaggcat
     8161 taagcgagca ggggtttaat acctcggcca tcgcccggca agaaaaagag attgcgcaaa
     8221 cgcttgggca gcagggaacg ctggtcggtg aaattctcac gctgcgcgca cagcaacagc
     8281 agttaagccg ccagattgcg gaggcggcgg aaagcattgc cgcccaggct cacggtcaag
     8341 ccaataatgc agcgacatct gcgggcgcca cccaggccgg tatttacgat cttatcgaaa
     8401 gcggtaaagg ggatcaggct gaacgcgcgc ttgaccgact gattgatatc gaccttgagt
     8461 atgtgaatca gatgaatgag ttgcgggtca atgccctgcg gtttaagcag ctcattgtga
     8521 ccttaaaaga cgcgcaaggg ctgagcgatg ccgaggaaac cgatgaaaaa cttaatcagt
     8581 tggttaaaat tttatcccgc cgccagcagc gtatagaaga tcctaccgtt cgcgcccaaa
     8641 tcgccgacgc gctggggaaa ataaaccagt acacgacact ggttaccctg tttcgtaagg
     8701 aaaacgccat ccgcgaccag cttcaaacgc ttatggccaa taacctcttt cagtttaccc
     8761 gcttcagtac ggaagtgtcg cagttggtga acgccatcga aaaacgaaac gaggctgggt
     8821 tagcgcgtct tacacacgcc agtcagcgtg ggcaaatagg gttagtgatc ttaggtatcc
     8881 tggcgctgtg ctcattaagt tttattcttt ggcgagtggt ttaccgttcc gtatcccgcc
     8941 cgctggcgca acaaacgcag gccttacagc ggctactgga gggcgatatt gactcgccgt
     9001 ttccggaggc ggctggcgtc agcgaactgg ataccatcag ccgtctgatg gaagcgtttc
     9061 gcgccaacgt gcgcaaattg aaccgccatc gtgaggattt ggcggaacag gtgcgatcgc
     9121 aaacggcgga gcttcatgcg ctggtgctgg aacaccggca ggcgcgcgcc gaagcggaaa
     9181 aggccaacga ggcgaaatcg acgttccttg ccgccatgag ccatgaaatt cgcacgccgc
     9241 tttacggcat tctcggtacg gtacaattgc tggccgataa accgctcatg gcaaactacc
     9301 gcgacgattt acaggccatt aatgattcag gcgaatcgct actggcgatt cttaacgata
     9361 ttcttgatta ctcggcgatt gaagtaggcg gcaccaacgt ttccattagc gaggaaccgt
     9421 ttgaaccgcg acaattgttg aatagcgcgc tgcatttaat gcacagccgc gtgcaggtgg
     9481 cgctcatcac cgactttagc gagcaactcc cttccacgct acaaggcgat ccgcgccgga
     9541 tacgtcaaat tgtgattaat cttttaagta atgcggcgaa atttaccgat cgcggcagca
     9601 tagtgctgcg cacgttttgc gacgatcaga gctggtttat tgaggttgaa gataccggat
     9661 gcggtatccc tgaagcgaag ctgacggcta ttttcaaacc gtttgtgcag gcgacaggat
     9721 gccggggcgg gacgggcctg gggctggcta tcagcgccag cctggcagag gcgatgggcg
     9781 ggacgctaac cgtcaccagt acgcttcatg ttggcagttg ttttcgctta caactgccgg
     9841 ttcgccaccc caaacctgca agcaaaagtg cgttcaggga accggtaaat cttaacggac
     9901 tacgcctgtt gctgattgaa gataatatgc tgacgcagcg tattaccgct gaaatgctca
     9961 cgggtaaagg ggtgaaggtc tcagtagctg aaagcgcgaa tgacgcgcta cgctgtttag
    10021 ccgaaggcga gccctttgat gtggcgctgg tggattttga tttaccggat tatgacggct
    10081 taaccctggc gcagcagttg atgagcctgt atcccgccat gaaacgcatt ggttttagcg
    10141 cgcatgtgat agacgataat cttcgtcagc gtaccgccgg tcttttctgc gggattattc
    10201 aaaagcccgt tccccgcgag gagctttacc gcatgatagc gcactattta cagggcaaat
    10261 ctcacaacgc gcgggtgatg ttgaatgaac atcagcttgc cggcgatatg gcgtctgtcg
    10321 gcccggaaaa gctccggcaa tgggtcgcct tattcaaaga cagcgcgctg cctttagtcg
    10381 aggagatcga ggcggcgcgc gccatgaatg acgacgttaa cattaagcgg ctggcgcata
    10441 aattaaaaag cggctgcgcc agcctgggga tgacgcaggc aaccgaagcc tgtcgggagc
    10501 tggaattgca accgcttagc gatatagata ttaaaactat cgtgacgcag ggagtgacgg
    10561 cgctcgacgc atggatagcc ggtcatcctt cgccatgatg atttccggct cgccaaacga
    10621 cgcgtttcac atcgccagtt atcaggacat aaaacagtac gccgagggta taagagggaa
    10681 atagcctacg gctaccgcct gtttaatgat tctgtgtttt ttcgtcctgt agccgtgcct
    10741 gctccgccag ggcggcaaaa tctttttcgc tgtaatagtg cgcgggaggc ggtagctgcg
    10801 ccatatcctc gctgggccac aattgtagct gcgccagcgt gctaagctgg ataccgcgcc
    10861 agcgatgggg caagctcagc ggcaatagcg acgttatctc gccaggaacc gcggtcggca
    10921 ggcggtcatc gcccatctga taattacgat gcagcaccag atatttttcc ggtacccgcc
    10981 gctggctgtt ccaccaacga ccatcaagca tatcaaactg aaaacgggtg atctgcgccg
    11041 gctgcgctgc cagctgcgtc agcgcttgcc gcagcgcagt ttccatcgcc gtgttgtaca
    11101 tctcttgcgt tttcgtctgg ccgtcgacaa ttaaagacgc cgccagacgg gcacccgcga
    11161 ggttagaata gagatcttcc ggcgaaaagg ccgatactcc ctcagaaaat ccgcgaacgg
    11221 actcgaaacc gtaccattgg gcgatttcgt gccactccgc cacctggaac gccagatgcg
    11281 ccgacagcca ggcggccagc gtgtaacgct cgcgtgcatc gaccggaggg gtaaaagcag
    11341 taaagaccag acgccgttcg gccagctcct cgcccagatt cagcgtaaaa gcctgcccca
    11401 gctttggtag tagttggctg aagatataca ctgtcatatc agcggtatcc cgcacatgtg
    11461 cggtgtcgat gaatccgcca cgcaaggtat acacaatacc gttattctca ccgctaaggc
    11521 cgatcaggtt tgccacgccc gagtacagat ggtcgttgta ctgatgatgc cccagcgagt
    11581 ctaccgtcac gacgttattt aactgataaa acggaaccgg cagtcccagc agctcggcat
    11641 gcaggtcgta accaaaagcg caacacggac gcaacccctt tggcagcggc tgtggcggca
    11701 tcgttggcca ggcttcactg gcagcaggca ttgggagcgt ggacagatag agcgtcagtg
    11761 gtaaggcggc gcgggcgctc cccgccagaa acagcagcgc cagaaagata acccgaacga
    11821 tagtcctcaa aatgcctctc ctacctgaaa ataaaaaccg ctgctgcctt tgcccacgcc
    11881 gtaatccagc cgcacgttga cgcgcggctt gaactcaaag cgatagccca cgcccgcaga
    11941 aggcagccat cgcccgtcat ccagatggtg caaagacgat cccatggtgc ccgctcccac
    12001 ccaaccgaca acgccatgcc gccagctcaa cttatggcga tattccagtt ggccactgac
    12061 ggcgttttta tcgcgatagc gcccttcata atagccgcgc atacgatggt tactgcccag
    12121 cagcggcagc atattccatg gcacgtagcc ctgggtaaag gcaccgtcag cttcccaggc
    12181 cagcacgtct ttatcatcaa cggcgtggta ttgactgtag tgcaactggt attcatcgaa
    12241 ccgcgtatcg ctaccgatgt ctggcgcgaa gtgggtatag cgaagggtgg catactgtcc
    12301 tttgcgtggg ttaggcataa aatcacggtc gtcccaacta atctcaacgc taccgccgtt
    12361 actcagtgaa gaaccgccct gcgctgtatg ttgaattctg ggcggatcgt cctcattgat
    12421 ttgcgcggcg tgctgtacat ccagcgtcca gccaacgcca agatagatat tgttgaccag
    12481 ccgacgatac agcatgggtt gcagatccag cacctgcgcg gtataggcct gcttatggct
    12541 gtctttatca ccggcggcaa aaccctgccc ccaatagtaa gtgggcgtgt cgctcaatgc
    12601 gccagtaagg aagaaacgcc agcgatcttg cgcgaaaaag gcgtaatttt gcaggcttac
    12661 gccgaaagcg cccgtggagc taaaatagcc gctcagcgac agcgtggata tctggctaac
    12721 cttatcggca ggatcggggc gatacatacc gacaatggcg gtgccgatgc ccagccccag
    12781 ttcaggggta taaaatggcc cgggcattac tccccagttg acgcctttgg cggcatcgta
    12841 agtatcgcta tcccccattt gttgtagcca gccgtccacc tgactgcggc tgggcagcgc
    12901 cgcctgcgcc acgccggaca gcacaccggc gacgcaaagc aactgtcggc aatggcagcg
    12961 gttcaaaagc gatactcacc ggccacaaag aagctgttgc gctcggcaaa gccaaactcg
    13021 gtggtaacgt tgaaatggcg ggttatttca tactgagcgc ccagcagcat gttccacggt
    13081 gattgcagat gctgtttgac gtcaaagcgg ccgttattgt tatagttagc catactcacc
    13141 agcctttgta gcgtcgctga tggcatggtc aggtcgtcga ggctgccttt aaactcctgc
    13201 tgcacatcct gatacatgct gccgacccag acgtttagct tgcccgacgg cagatgcatc
    13261 ttatctatac ccggggtggt aaaacggtaa ccaacgcgag gtgagacggt aaaggcgtcg
    13321 atgctgccat caagaatatc gaactgtgtc tgggtgtagt tagcatcaac agcggtaaac
    13381 cagttaccta cgccgccgac cagcgtggtg ccgataccat aggtagtgcc tttaaagtcg
    13441 agtttaaact tgaggttttg cagatcggcg ggatgaaaaa cgtggccatt tttcgtcatc
    13501 aacccaacac caatttgcga aac
//
LOCUS       DAJVKX010000121        13519 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.121, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000121 DAJVKX010000000
VERSION     DAJVKX010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13519
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.121"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..6946
                     /gene="bapA"
                     /locus_tag="OPY25_003530"
     CDS             <1..6946
                     /gene="bapA"
                     /locus_tag="OPY25_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="biofilm-associated protein BapA"
                     /protein_id="HCS0929044.1"
                     /translation="VTSALPDGVYPLTAIAADAAGNSSGVSNSFTFTVDTVPLQPPVV
                     NEILDDVAPVTGPLTDGAFTNDRTLTINGSGENGSTVTIYDNGVAIGTALVTDGVWTF
                     NTSELSEASHALTFSATDDAGNTTAQTQPITITVDITAPPAPTIQTVADDGTRVAGLA
                     DPYATVEIHHADGTLVGSAVANGTGEFVVTLSPAQTDGGTLTAIAIDRAGNNGPATNF
                     PASDSGLPAVPAITAIEDDVGSIQGNIAAGGATDDTMPTLRGTTDIGSTVEVFIDGDS
                     AGFATVDASGNWIFEIATPLSESTHYFTVQATNANGPGGLSAPVGITVDLSAPAQPVI
                     TSATDDVPGMTGTLDNGALTNDSRPTLNGTGEAGATIRILDNGVEIGSATVDQSGNWR
                     FTPNTPLESNAHIFTAVATDPAGNSGQLSDGFTLNIDAQAPDVPVITSVIDDNNQPTV
                     PVLPGQSTDDRQPILNGTGEPGATITIFDNGTPLGTAQVGENGSWTFPVPRNLSEGSH
                     NLTVSATDPAGNTSAVSAPWTIVVDITPPAIPVLTSVVDDQPGITGNLVSGQLTNDAT
                     PTLNGRGEAGATINVYLDGNPASIGTTTVNSDGTWSFTPQTPLANGSHTFTLSATDPA
                     GNSSAVSSGFVLTIDTTPPAAPVIASVADNTAPVTGIVPNGGSTNETRPTLSGTGEAG
                     TTISIYNGSALVGTAQVQANGSWSFTPSTSLGAGVWNLTATATDAAGNTSAASEIRSF
                     TIDTTAPAAPVIDTVYDGTGPITGNLSSGQITDEARPVISGTREANTTIRLYDNGTLL
                     AEIPADNSSSWRYTPDASLATGNHVITVIAVDAAGNASPVSDSVNFVVDTTPPLTPVI
                     TSVSDDQAPGLGTIANGQNTNDPTPTFSGTAEAGATITLYENGTVIGTTTAQPDGAWS
                     VSTSTLASGTHVITAVATDAAGNSSPNSTAFTLTVDTTAPQTPILTSVVDDVAGGVTG
                     NLANGQITNDNRPTLNGTAEAGSVVSIYDGDTLLGVTSANASGAWSFTPTTGLNDGTR
                     TLTVTATDPAGNVSPATSGFTIVVDTLAPTVPLITSIVDDVPNNTGAIGNGQSTNDTQ
                     PTLNGTAEANSAVSIFDNGALVATVNANASGNWSWTPTASLGQGSHAYSVSAADAAGN
                     VSAASPSTTIIVDTIAPGAPGNLVINATGNRVTGTAEAGSTVTITSETGVVLGTATAD
                     GTGSFTATLTPAQTNGQPLLAFAQDKAGNTGIAAGFTAPDTRVPEAPIITNVVDDVGI
                     YTGAIANGQVTNDAQPTLNGTAQAGATVSIYNNGALLGTTTANASGNWSFTPTGNLTE
                     GSHAFTATATNANGTGSVSTAATVIVDTLAPGTPSGTLSADGGSLSGQAEANSTVTVT
                     LAGGVTLTTTAGSNGAWSLTLPTKQIEGQLINVTATDAAGNASGTLGITAPILPLAAR
                     DNITSLDLTSTAVTSTQNYSDYGLLLVGALGNVASVLGNDTAQVEFTIAEGGTGDVTI
                     DAAATGIVLSLLSTQEIVVQRYDTSLGTWTTIVNTAVGDFANLLTLTGSGVTLNLNGL
                     GEGQYRVLTYNTSLLATGSYTSLDVDVHQTSAGIISGPTISTGNVMADDTAPTGTTVT
                     AITNANGVSTPVGAGGVDILGQYGTLHINQDGSYTYTLTKPTAGYGHKESFTYTITQN
                     GVGSSAAQLVINLGPAPVPGSVIATDNNASLVFDTHVSYVNNGPSTQSGVTVLSVGLG
                     NVLNANLLDDMTNPIIFNVEEGATRTMTLQGTVGGVSLVSTFDLYVYRFNDAIQQYEQ
                     FRVQKGWINTLLLAGQSQPLTLTLPGGEYLFVLNTASGISVLTGYTLAISQDHTYAVD
                     SITANTTGNVLTNDVAPTDALLTEVNGVAIAATGTTEVNGLYGSLIIDARGNYTYTLK
                     NGVGADSIKTPDSFIYTLKAPNGDTDTASLNITPTARALDAINDVSDTLSVATLQDTA
                     AWLDSSVGSASWGLLGKSGSGSGTFDVATGTVLKGASLVFDVSTLITLGNLNISWAIQ
                     ENGTVIRNGTVPVANITLGSATVTVNLSGLELDAGTYTLNFTGTNTLAGAATITPRVI
                     GTTVDLDNFETSGTHTVLGNIFDGSDAAGAMDQLNTVNTRLSISGYNGSAATLDAAAN
                     TTSATIQGHYGTLQINLDGAYTYTLNNGVAMSSITSKEVFTYQLDDKIGHTDSATLTI
                     DMAPQIVSTNQNDVLIGSAYGDTLIYHLLNGADATGGNGADRWQNFSTAQGDKIDIHE
                     LLTGWDHQAATLGNFVQVHTSGANTVISVDRDGAGSAFKSTDLVTLENVQLTLNDLLQ
                     NNHLITGG"
     gene            7010..8419
                     /locus_tag="OPY25_003531"
     CDS             7010..8419
                     /locus_tag="OPY25_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family outer membrane protein"
                     /protein_id="HCS0929045.1"
                     /translation="MGRVAPVAIVLAFALFHHQPRGAEALPMITSEGLATDQMLPSLD
                     GSAAELPLSAAAPGNLTLNDAVNRAVNWHPSIREAVGKLLAQNEQIEVAKSKYYPQVS
                     AGVNNGYSNTYTDHGYSPSLVLSVSQMLYDFGKVASQVRAETAGAAQQQANVLLSIDT
                     VAHETANAIVQTQSWQQMVEAAEEQLVALDSIGKLIRQRSDEGATSLSDVVQTEARIE
                     SARSQLAQYQANLDSAKASLMSWLGWNSLNGINNDFPAKLARSCETATPEDRLVPAVL
                     AAWAQANVARANLDYASAQMTPTISLEPSVQHYLNDKYPSHEVLDKTQYSTWVKVEMP
                     LYQGGGLTARRNAASHAVDAAQSTIQRTRLDVRQKLMEARSQAMSLASALQILRRQQQ
                     LSERTRELYQQQYLDLGSRPLLDVLNAEQEVYQARFAELQTESQLHQLQLNYLYNTGA
                     LRQAFALNHRSIQSVEIQP"
     gene            8416..10596
                     /locus_tag="OPY25_003532"
     CDS             8416..10596
                     /locus_tag="OPY25_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HCS0929046.1"
                     /translation="MTRAAPDVEEVLSERALSQWAQAISHVAGHYRVACSPGSIQANA
                     PWFRGKSRTTALTQLARQAGLSFHAPDIDKTAFSQWRLPLVVELRDGQLLVIEHVNGE
                     DAVDVFVIEEEGQRNRLTLSELLPEILYVAALRPLSALKDSRVDRYISRFKPDWMREL
                     VLQDIRPYLPVMVAAFLINVLSLAGIVFSMQVYDRVIPAQSYPTLYVLSFGVLVAVLF
                     GFLLREARTHIMDVLGKRADMRISDRVFGHALRLRNSAIPRSTGSFISQLRELEQIRE
                     MITSSTLATIVDLPFFFLFMIVLAIIAPPLAWIAPVAALLMILPGVALQKKLAVLANQ
                     AAHEATLRNAVLVESVQGLEDIKLMQAENRFLQQWNSYIRITGESGLRTRKLTQRLIS
                     WGMSVQSLVYAAVIMFGAPMVIEGSMTTGAVVAASMLGSRMIAPMANLCGVLARWQQV
                     KAAKMGLDNIMQLPTETQHDDSLIHRDILHGHYLFENAQFRYHNDDQRIPLRLVRLEI
                     MPGERIAILGRNGAGKSTLLQAMAGGLEMIQGDARLDNLSLSHIDMADLRRNIGFLSQ
                     NARLFFGTLRENLTLGAPHANDEQIFDALEVSGGAVFVRRLAKGLDHPIMEGGNGLSG
                     GQRQSLLLARMLLRSPNIVLLDEPSASLDEHTEREFIQRLHQWLGNRTLVVATHRVPI
                     LELVERVVVLKEGQLVMDAPKAQALNADRMQSHRREWKNENQSA"
     gene            10604..11767
                     /locus_tag="OPY25_003533"
     CDS             10604..11767
                     /locus_tag="OPY25_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion periplasmic adaptor
                     subunit"
                     /protein_id="HCS0929047.1"
                     /translation="MDDFDIQRERAFSGAGRIVLICSLLFLILGIWAWFGRLDEVSTG
                     NGKVIPSSREQVLQSLDGGILAQLTVREGDRVQANQIVAQLDPTRLASNVGESAAKYR
                     ASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALAS
                     VNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEV
                     DMLSAILKGREDSVTRLTIRSPVRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIE
                     TRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGVVETISPDTIQDKVKPEIFYYRVF
                     IRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER"
     gene            11839..12201
                     /gene="ssrA"
                     /locus_tag="OPY25_003534"
     tmRNA           11839..12201
                     /gene="ssrA"
                     /locus_tag="OPY25_003534"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(12310..13083)
                     /locus_tag="OPY25_003535"
     CDS             complement(12310..13083)
                     /locus_tag="OPY25_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
                     /protein_id="HCS0929048.1"
                     /translation="MTIEVQRWEDKFEIKPGVWVYVPSVEARKVGGKILQAVRNKWIP
                     PLYFYHLRTGGHLKAARLHLKSDFFAVVDIKQFFQSTSRSRITRDLKSYFTYSQAREI
                     STFSTVRNLSHSPHKHVLPFGFVQSPILATLCLDKSYFGSLLRRLNKHHDLKLSVFMD
                     DVIISSNNLAQLQAAYDEALVAMRKSGYQANMSKTQAPSSKISVFNLTLSKGVMKVTS
                     QKMSDFLIDFYSSNYEPHRIGVKNYVEAVNPGQAKLFKL"
     gene            complement(13052..13225)
                     /locus_tag="OPY25_003536"
     CDS             complement(13052..13225)
                     /locus_tag="OPY25_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001384722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929049.1"
                     /translation="MDTNELGLVKARVELITAMLKCATAFVGLVGAVYAVLNMAFNYN
                     NLTHDNRSSKVGR"
BASE COUNT         3154 a         3898 c         3693 g         2774 t
ORIGIN      
        1 ggtgaccagc gcgttgccgg atggcgtcta ccccctgacc gccattgccg ccgatgccgc
       61 cggaaacagc agcggcgtat cgaacagctt taccttcacc gtcgacaccg ttccgttgca
      121 gccgcccgtc gtcaatgaga tcctcgacga tgttgcacca gtgaccgggc cattaaccga
      181 tggcgccttt actaacgatc ggacgctgac tattaacggc agcggcgaaa acggcagcac
      241 cgtcacgatt tacgacaatg gcgtggcaat cgggacggcg ctcgttaccg acggggtctg
      301 gacattcaat acgtccgaat tgtcagaagc cagccatgcg ctaaccttca gcgcgactga
      361 cgatgctgga aataccacgg cgcaaaccca accgatcacc attaccgtgg atatcaccgc
      421 cccgcccgcg ccaacgatcc agacggtggc cgatgatggc acgcgcgtcg ccggacttgc
      481 cgatccttac gctaccgttg aaattcatca tgccgatggc accctggtcg gcagcgctgt
      541 cgctaatggc accggtgaat ttgtcgtcac gctcagtccg gcgcaaaccg atggcggtac
      601 gctgacggca attgctatcg atcgcgcggg gaataacggc ccggctacga attttcctgc
      661 ttccgacagc ggtctgcccg ccgtcccggc catcacggcg attgaagatg atgtcgggag
      721 catacagggg aatattgcag cgggcggcgc cacggacgac accatgccga cgctgcgcgg
      781 caccacggat atcggctcta ccgttgaagt tttcattgat ggcgattcgg caggctttgc
      841 caccgttgac gccagcggga actggatctt tgagatcgcg acgccattaa gcgaaagcac
      901 acattacttc accgtccagg caaccaatgc gaatggcccg ggcggcctgt ccgcaccggt
      961 cgggatcact gtcgatctta gcgcgccggc acaaccggtt attaccagcg caacggatga
     1021 tgtccccggc atgaccggta cgctggataa cggcgcgctc accaatgatt cacgcccgac
     1081 gctcaacgga acgggagaag caggcgccac aatccgcatt ctggataacg gcgtagaaat
     1141 cggttccgct acggtagatc aaagcggcaa ctggcgcttc accccgaaca cgccgctgga
     1201 gagcaacgca cacatcttta ccgccgtggc gaccgatccc gccggcaata gcggtcagct
     1261 ttcggatggt tttacgctga acattgacgc gcaggcacca gatgtgccgg ttatcacctc
     1321 cgtgattgac gataacaatc aaccgaccgt cccggtgtta ccggggcaat ccaccgacga
     1381 tcggcagcca atactgaacg gaactggcga acctggcgcg acaatcacca tttttgataa
     1441 cggtacgccg cttggcacgg ctcaggtagg cgaaaacggt agctggacct tcccggtgcc
     1501 ccgcaatttg tcagagggaa gccataatct gacggttagc gctaccgatc cggcgggcaa
     1561 taccagcgcg gtctccgcgc cgtggacgat cgtggtcgat attacgcctc cggcgatccc
     1621 ggttctcacc tccgttgtgg atgaccagcc cggtattacc ggcaacctgg ttagcgggca
     1681 gctaacgaac gatgcgacgc ccaccctgaa cgggcgcgga gaggcaggcg cgacgattaa
     1741 tgtctatctt gacggtaatc ccgcgtccat cggtaccacg acggtgaata gcgacggcac
     1801 gtggagtttc acgccgcaga cgccgcttgc aaacggtagc cacacgttca cccttagcgc
     1861 caccgatccg gcgggtaata gcagcgcggt gtccagcgga tttgtgctga cgattgacac
     1921 cacaccgccc gccgcgccgg ttatcgccag cgtggcagat aatacggcgc cggtaacggg
     1981 catcgtcccc aacggcggct cgacgaacga aacccgacca acactctcgg gtaccggtga
     2041 ggcgggtaca accatctcga tttataatgg cagcgcgctg gtcggcacgg cgcaagttca
     2101 ggccaacggt agctggagct ttacaccgtc tacctcgctg ggcgcgggcg tctggaacct
     2161 gacggcgaca gcaaccgatg cggcaggcaa taccagcgcc gcgtccgaaa tacgctcgtt
     2221 tactattgat accacggctc ccgccgcgcc tgttattgat acggtctacg acggtacggg
     2281 ccccattacc ggcaatctga gttcagggca gatcacagac gaggcgcgcc ctgtcattag
     2341 cggcacccgt gaagccaaca caactattcg tctctacgat aacggcacgc tgctggctga
     2401 aattcccgcc gacaatagca gtagctggcg ctacacgccc gacgcctcgc tggcgacggg
     2461 caaccatgta attaccgtca ttgccgttga tgccgcaggc aacgccagcc ccgtttcgga
     2521 cagcgttaat ttcgtcgtcg ataccacgcc gccgctgacg ccggtaatca catcagtcag
     2581 tgacgatcag gcgccaggcc tcggcacgat cgcgaacggc caaaatacca acgatcctac
     2641 gccaaccttc agcggcaccg cagaagccgg cgccacgatc acgctctatg aaaatggtac
     2701 ggtcattggc acgacaacgg ctcagcctga cggcgcgtgg agcgtctcca cctcaacgtt
     2761 ggcaagcgga acgcacgtca tcaccgccgt cgccaccgat gccgcaggaa acagcagccc
     2821 gaacagtacg gctttcaccc tgacggtcga taccaccgcg ccgcaaacgc caatcctgac
     2881 gtccgtggtg gatgacgtcg cgggcggggt cacaggaaat ctcgctaatg gtcagataac
     2941 caatgataac cgccccacgc tgaacggcac tgccgaagcg ggcagcgtgg tcagtatcta
     3001 tgatggcgac actctgcttg gcgtcacctc ggctaacgct agcggcgcat ggagcttcac
     3061 gccgacgaca gggttaaacg acggcacgcg cacattaaca gtgaccgcca ccgacccagc
     3121 aggcaacgtt agcccggcca ccagcggttt tactatcgtg gtcgataccc ttgcgccaac
     3181 ggttccgctt ataaccagca tcgttgatga tgtcccgaac aataccggcg ccattggcaa
     3241 tggacaatcg accaatgaca cacagccgac gctcaacggt accgcggaag ccaacagcgc
     3301 ggtaagtatc ttcgataatg gcgcgctggt cgcgaccgtg aacgccaatg ccagcggcaa
     3361 ctggagctgg acgccaaccg cctcgctcgg ccagggaagt catgcctata gcgttagcgc
     3421 cgccgatgcg gctggcaacg ttagcgccgc ttcgccatcg acaacgatta tcgtggatac
     3481 cattgcgccc ggcgcgcccg gtaacctagt catcaatgct accggtaatc gggtgacggg
     3541 caccgcggaa gcaggcagca cagtgacgat tacctctgag actggtgtgg tactgggaac
     3601 cgccaccgcc gacggtacgg gcagcttcac cgccacactc acgcccgcgc agaccaatgg
     3661 tcagccgcta ctggcatttg cccaggataa agcaggcaac actggcattg ccgccggatt
     3721 taccgcgccc gatacgcgcg tgccggaagc gccgatcatc accaacgtag tggatgatgt
     3781 gggtatttat accggcgcta tcgccaacgg tcaggtcact aatgacgcac aacccacatt
     3841 gaatggtacc gctcaggcgg gcgccacggt gagcatttat aacaacgggg cgctgctcgg
     3901 caccaccacg gcgaacgcca gcgggaactg gagctttacc ccgacaggca atttgaccga
     3961 aggcagccac gccttcaccg ctaccgcaac taacgccaac ggtacaggca gcgtctccac
     4021 cgccgcgacg gtgattgtcg atacgctggc gcccggtacg ccgtcaggta cgctcagcgc
     4081 cgatggcggt tcactttccg gacaggctga ggcaaacagc accgtaaccg taacgctggc
     4141 ggggggcgtg acgctcacca ccaccgccgg cagcaacggc gcatggtctc tcaccttgcc
     4201 gacaaaacaa attgaaggtc aactcattaa cgtgacggcc actgacgctg cgggtaacgc
     4261 ctccggcacg ttaggcatta ccgcgccgat tctgccgctg gcggcaaggg ataacataac
     4321 cagtcttgat ctgacctcta ccgccgtcac cagcacgcaa aactattcgg attacggcct
     4381 gctgctggtt ggcgcgcttg gcaatgtcgc ctcggttttg ggtaacgata ccgctcaggt
     4441 tgagttcacc attgctgaag gtggtacggg cgacgtcacc atcgatgccg ccgcaacggg
     4501 aatcgtgctt tcgctgctca gcactcagga gatagtggta cagcgctatg acaccagcct
     4561 cggcacctgg acgacgatcg tcaacaccgc cgttggcgac ttcgcgaatt tgcttaccct
     4621 gaccgggagc ggcgttaccc tgaacctgaa cggactgggc gaaggccagt accgggtact
     4681 cacttataac accagtctgc tcgccaccgg gtcatatacc agcctggatg tcgatgtaca
     4741 ccagaccagc gcaggtatta ttagcgggcc aaccatcagt accggcaacg tcatggctga
     4801 tgataccgcg ccgacgggca ccacggtcac cgccatcacc aacgccaacg gcgtcagtac
     4861 gccggtcggc gcgggcggcg tggatatcct ggggcaatac ggcacgctgc acattaatca
     4921 ggatggcagt tacacctaca cgctgactaa gcccacggcg ggatacggac ataaagagag
     4981 cttcacctac accatcaccc agaatggcgt cggtagcagc gccgcgcaac tggttattaa
     5041 tttgggtccc gcgcctgtac cgggcagcgt gatagcgaca gacaataacg cctcgctggt
     5101 ctttgatact cacgttagct acgtcaacaa cggcccctcg acacaaagcg gcgtcacggt
     5161 attaagcgtc ggacttggta atgtactgaa cgcgaatctg cttgatgata tgactaatcc
     5221 gatcatcttt aacgttgaag aaggcgctac gcgaaccatg acgttacagg gaaccgtcgg
     5281 cggcgtctca ctggtttcca cgttcgatct gtacgtttat cgcttcaacg atgccattca
     5341 acaatatgag cagttccggg tgcaaaaggg ctggattaac accctgctgt tagccggaca
     5401 gtcccagccg ctgaccctga cgttgcctgg cggcgaatac ttgttcgtgc tgaataccgc
     5461 cagcggcatt agcgtcctca ctggctatac gttggcgatt tcccaggacc acacctatgc
     5521 cgttgacagt atcaccgcca acaccaccgg caacgtactg accaatgatg tcgcccctac
     5581 ggacgccctc ctcactgaag taaacggcgt ggcgattgcg gcgaccggca cgacggaggt
     5641 aaatgggctg tatggctcgc tcatcattga cgcaagaggc aactatacct acacgctgaa
     5701 gaacggcgtc ggcgccgaca gcattaaaac gccggacagc tttatctata cgctcaaagc
     5761 gccaaacggc gataccgata cggcctcgct caatatcacg ccaaccgcca gggcgctgga
     5821 tgcgattaat gatgtcagcg atacccttag cgtcgccacg cttcaggata ccgctgcctg
     5881 gctggactcc agcgtcggca gcgccagttg ggggctactc ggcaaatcgg gcagcgggag
     5941 cggcaccttt gacgttgcaa cgggcaccgt acttaaaggc gcgtcactgg tctttgatgt
     6001 ctccacgctc attacgctgg gcaatctgaa tattagctgg gccattcagg agaacggaac
     6061 cgtcatacgc aacggaaccg tcccggtggc gaatatcacg ctgggcagcg cgacggtgac
     6121 cgtcaacctg agcggcctgg agctggatgc cggaacgtac acgcttaact ttaccggcac
     6181 caataccctg gccggggcgg cgacaatcac gccacgcgtc atcggcacca ccgtcgatct
     6241 ggataatttt gaaacgtccg gaacgcatac cgttctcggc aatatttttg acggcagcga
     6301 cgcggcgggg gcgatggatc agcttaatac ggtgaatact cgcctgagca ttagcgggta
     6361 taacggcagc gccgccacgc tggacgccgc ggcgaatacc accagcgcca cgattcaggg
     6421 acattacggc acattgcaaa ttaacctcga tggcgcttac acctacaccc tgaataatgg
     6481 cgtcgcgatg tcgtccatca ccagtaaaga ggtctttacc tatcaactgg atgacaagat
     6541 aggtcatacg gatagcgcca cattgaccat tgatatggcg ccgcaaatcg tcagtaccaa
     6601 ccaaaacgat gttcttatcg gctccgccta tggcgatacg ctgatttatc acctgttaaa
     6661 cggcgcggac gcgaccggcg gcaacggcgc cgatcgctgg caaaacttct ccaccgcgca
     6721 gggcgacaag atcgatatcc acgaactgct gaccggctgg gatcaccagg cggcgacgct
     6781 aggtaacttt gttcaggttc ataccagcgg cgccaatacg gtgatatccg tcgatcgcga
     6841 cggcgccggc agcgcgttta aatcaactga ccttgtcact ttggagaatg tgcagctcac
     6901 gctaaatgat ctgttgcaga acaaccacct gataaccggc ggttgataaa aagccccgaa
     6961 cgccacgacg ttcggggcaa caagcggtga tatttaaaag ggataaacta tgggaagagt
     7021 cgcgcctgtc gccatcgtac tggcatttgc tttgtttcat caccagcccc ggggcgcaga
     7081 agcgctgcca atgattacat ccgaaggatt agcaacggac cagatgcttc cttcgctgga
     7141 tggctccgcc gctgagttgc cgctcagcgc cgccgcgccg ggcaacctga cgctcaatga
     7201 cgcggtcaat cgcgccgtta actggcatcc ttctattcgc gaagccgtcg gcaaactgct
     7261 cgcacagaat gaacaaatag aggtcgccaa atcgaaatat tatccgcaag tcagcgctgg
     7321 cgtgaacaat gggtacagca atacctacac cgatcacggg tatagcccct cgctggtgct
     7381 gtcggtatcg caaatgcttt atgacttcgg caaagtggca agccaggttc gcgccgaaac
     7441 cgcaggcgca gcacagcaac aggccaacgt gttgctcagt attgataccg tcgcgcacga
     7501 aaccgccaac gccattgtac aaacgcagag ctggcagcaa atggtagaag cggcggaaga
     7561 acagctcgtc gcgctggaca gcatcggtaa acttatccgg cagcgcagcg atgaaggcgc
     7621 tacgtcgcta tctgacgtgg tgcaaaccga agccagaatc gaatccgccc gctcgcaact
     7681 ggcgcagtat caggccaatc tcgacagtgc gaaagcctca ctgatgagct ggctgggctg
     7741 gaattcgctt aacggcatca ataatgactt cccggcgaaa ctcgctcgca gctgtgagac
     7801 agcgacgccc gaagatcggc tggtgcccgc ggtactggcc gcctgggcgc aggccaacgt
     7861 tgcgcgggcg aatctggact atgccagtgc gcaaatgacg ccgacgattt cgctcgaacc
     7921 ttctgtacaa cattatctta atgacaaata tcccagtcat gaagtgctgg ataaaaccca
     7981 gtattccacc tgggtgaaag ttgagatgcc gctttatcag ggcggagggc tgactgcccg
     8041 acgcaacgcc gccagccatg cggtagacgc ggctcagtcg accattcagc gcacccggct
     8101 tgatgtccgc cagaaactga tggaggcgcg cagccaggca atgagtcttg ccagcgcgtt
     8161 acaaatcctt cgtcggcaac agcagcttag cgaacgcacg cgcgaactgt atcagcagca
     8221 ataccttgac ctcggttccc gcccgttgct cgacgtgctt aatgcggagc aggaggttta
     8281 ccaggcgcgt tttgccgaac tgcaaacgga aagccagttg catcagttac aactgaacta
     8341 tctgtataac accggcgcgc ttcgtcaggc gttcgcgtta aatcatcgca gcattcaatc
     8401 cgtggagatc cagccatgac ccgcgccgcc cccgatgtag aagaggtact cagtgagcgc
     8461 gcgctaagcc aatgggcgca ggccatcagc catgtcgccg gtcattatcg cgttgcctgt
     8521 tctcccggtt caattcaggc caacgccccg tggtttaggg gtaaaagcag aacgaccgcc
     8581 ttaacgcagc tcgcgcggca ggcgggttta tcctttcatg cgccggacat agacaaaacg
     8641 gcatttagtc agtggcgatt gccgttggtt gtcgagctcc gggacgggca gttattggtc
     8701 atcgaacatg ttaatggcga agatgcggta gacgtttttg tgattgaaga agagggtcag
     8761 cgtaaccgcc tgacgctcag cgagttattg ccggagatcc tctatgttgc cgcgctacgc
     8821 ccgctatcgg cgctcaagga tagccgcgtc gaccgctata tctcccgctt taaacccgac
     8881 tggatgcgcg agctggttct gcaggatatt cgcccttatt taccggtaat ggtcgccgcc
     8941 tttctgatta acgtgctgtc tctggccggg attgtgttct ctatgcaggt ttacgatcgg
     9001 gtgatccccg ctcagtcata tcctaccctg tacgtgctct ccttcggcgt gctggtagcg
     9061 gtgctgttcg gttttctgct gcgtgaagcg cgtacgcaca ttatggacgt gctcggtaaa
     9121 cgcgccgata tgcgcatttc cgatcgggta ttcggtcatg cgttaaggct gcgcaacagc
     9181 gctatccccc gttccaccgg cagttttatc tcgcagttac gtgaactgga gcagatccgc
     9241 gagatgatta cctcttcaac gctggcgacc attgtcgatc tgcctttctt tttcctgttt
     9301 atgatagtct tggcgattat tgccccaccg ctggcatgga tagcgcccgt ggcggctctg
     9361 ctgatgatcc tgccgggcgt cgcactgcaa aaaaaactgg ctgtcctcgc caaccaggcc
     9421 gcccacgaag cgacgctacg caatgcggtc ttggtcgaaa gcgttcaggg gctggaagat
     9481 attaaactga tgcaggcgga gaaccgcttt cttcagcagt ggaatagcta tatccgtatt
     9541 accggcgagt cgggtctacg cacccgcaaa ctcacgcaaa ggcttatcag ttgggggatg
     9601 tcggtacaaa gtctggtgta tgccgcagtg attatgttcg gcgcgccgat ggtcattgaa
     9661 ggcagtatga ctaccggcgc cgtggtcgcc gcgtcgatgc tcggctcacg gatgatcgcg
     9721 ccaatggcta acctgtgcgg cgtgctggcg cgctggcagc aggtgaaagc ggcgaagatg
     9781 ggtctcgaca acattatgca actgcccact gagacacagc atgacgatag cctgatacac
     9841 cgcgacatcc tccacgggca ttacctcttt gaaaacgctc agtttcgtta ccataacgac
     9901 gatcaacgca taccgctgcg cctcgtgcgt ctggagatca tgccaggcga gcggattgcg
     9961 atactggggc gtaacggtgc gggtaaatcc acacttttac aggcgatggc gggcggcctg
    10021 gagatgattc agggagatgc ccggcttgat aatctcagct tgtcgcacat cgatatggcg
    10081 gatttacgcc gcaacatcgg ctttcttagc cagaacgcgc ggcttttctt cggcacccta
    10141 cgagagaacc tgacgctcgg cgcgccgcac gccaacgatg aacagatttt tgacgcgctc
    10201 gaagtcagcg gcggcgccgt cttcgtcagg cggctggcaa aagggttgga tcatcccatt
    10261 atggagggtg gtaacggcct gtccggcggg cagcgtcagt ccctgttgct ggcgagaatg
    10321 ctgctgcgct cccccaatat tgtgctactt gacgaaccca gcgcctcgct ggacgagcat
    10381 acggaacgag agtttattca gcggttacat cagtggcttg gcaaccgtac cctggtcgtc
    10441 gcaacgcacc gggtaccaat actggagctg gttgagcgtg tcgttgtcct gaaagaagga
    10501 caactggtga tggacgcgcc aaaagcgcag gcgcttaacg cggatcggat gcaaagtcac
    10561 cgtcgggagt ggaaaaatga aaatcaatca gcatgatgcc gcgatggacg atttcgatat
    10621 tcagcgtgaa cgggcgtttt ccggcgcggg tcgtattgtt ctgatctgct cactgttatt
    10681 tctcattctc ggcatctggg cgtggtttgg ccgactggat gaggtttcca ccggcaacgg
    10741 gaaagtaatc cccagttcac gcgaacaggt tctgcagtcg ctggatggcg gcattctggc
    10801 gcagttgacg gtgcgggaag gcgacagagt tcaggctaac cagattgtcg cccagcttga
    10861 tccgacgcgt ctggcgtcca atgttggtga aagtgcggca aaatatcgcg cttcactcgc
    10921 ctccagcgca cggttaaccg cggaagtcag cgacttacct ctcgccttcc ccgctgagct
    10981 gaacggctgg ccggatctga ttgccgcaga gacgcgtctc tataaaagcc gccgcgcgca
    11041 gctggccgat accgaagccg agctacggga tgcgctggcg tcggttaata aagagctgac
    11101 cattacccag cggctggaga aaagcggcgc ggccagtcat gttgaagtgc tacgcctgca
    11161 acgacaaaaa agcgatttag gcttaaaaat taccgatctg cgctcacaat attatgtgca
    11221 ggcacgcgaa gcgttatcaa aagcgaacgc tgaggtcgat atgctctccg ccattttaaa
    11281 aggacgcgag gattccgtca cccgccttac catacgttcg ccggtacgcg gcattgttaa
    11341 aaatatccag gtcacgacga ttggcggcgt gatcccgcct aacggtgaga tgatggagat
    11401 agtgccggta gacgatcgtc tgttgattga aacccgcctt tcgccgcgtg atatcgcctt
    11461 tattcatccc ggccaacgcg cattggttaa aattactgct tacgattacg ccatttacgg
    11521 cgggcttgac ggcgtggtgg agaccatttc accggatacc attcaggata aagtgaaacc
    11581 ggaaattttc tactatcgcg tgtttatccg cacccaccag gactatctac aaaataaatc
    11641 aggacgccgt ttttcgattg ttccaggcat gatcgccacg gtggatatca aaaccggtga
    11701 aaaaaccatt gtcgactatt taatcaaacc gtttaatcgc gcgaaagaag cgctgcgcga
    11761 gcggtaaatc gctgaagata agaagatacg ggggctggtc acgcgtgtca caagtctgtt
    11821 atacttacct tacacattgg ggctgattct ggattcgacg ggatttgcga aacccaaggt
    11881 gcatgccgag gggcggttgg cctcgtaaaa agccgcaaaa aaatagtcgc aaacgacgaa
    11941 acctacgctt tagcagctta ataacctgct tagagccctc tctccctagc ctccgctctt
    12001 aggacgggga tcaagagagg tcaaacccaa aagagatcgc gcggatgccc tgcctggggt
    12061 tgaagcgtta aaacgaatca ggctagtctg gtagtggcgt gtccgtccgc aggtgccagg
    12121 cgaatgtaaa gactgactaa gcatgtagta ccgaggatgt aggaatttcg gacgcgggtt
    12181 caactcccgc cagctccacc aaataaatca aggggttacg tgaaagcgta gccctttttt
    12241 ctttggtagt ggcggcaaaa tggcggcagg cattcagtca agcccagttg ctactacatg
    12301 cgatcgcaat tacaacttaa agagtttcgc ttgccctgga ttaacagctt cgacgtagtt
    12361 tttgacccct attctgtgcg gctcataatt gcttgaatag aaatcaatca ggaagtcact
    12421 cattttctga gatgtgactt tcataactcc cttactcaaa gttaaattaa acacgctaat
    12481 ctttgacgat ggtgcctgag ttttactcat gttggcttga taaccagatt tacgcattgc
    12541 cactagtgct tcgtcgtaag ccgcttgtaa ttgggccaaa ttgtttgacg agatgatcac
    12601 atcatccata aacacactta gcttgagatc atgatgtttg ttcaatcggc gtagtaagct
    12661 accaaaataa cttttatcta agcagagggt tgcaagtatt ggagattgaa caaaaccaaa
    12721 agggaggaca tgcttatgtg gactatggga caagtttctt acagttgaaa atgttgagat
    12781 ttcccgcgct tgagaatagg tgaagtagct ctttagatca cgggtgatac gactacggct
    12841 cgttgactga aaaaattgtt taatatcaac aacggcaaaa aaatcacttt ttaagtgtaa
    12901 tctggcagct ttaagatgcc caccagttct tagatggtaa aaatagagtg gcggaatcca
    12961 cttgtttctg acagcctgaa gtatcttccc tccgacttta cgtgcctcaa cgcttgggac
    13021 ataaacccaa accccgggct taatctcaaa tttatcttcc cacctttgaa cttctattgt
    13081 catgagttaa attgttgtag ttgaaggcca tgttaagaac ggcgtaaacc gcaccaacta
    13141 agccaacaaa cgcggttgcg catttgagca tagcggtgat cagttcaaca cgcgccttaa
    13201 ctaagccaag ttcgtttgta tccataactt gttcctccat agatacctga cgtctcttag
    13261 cgcaagcgca tggccctaac taaataaaaa ataacaacca gttagcccag aaagcttaac
    13321 aagtcggcgt ccgattacat ggcaaccagg taatcggtcc gcagtcgcaa agcgacaaac
    13381 tacatatcta cggagtgggg ataaatcccc gctaacgtca ggcattgtta atttaacctc
    13441 aacttataga aaagtatagt tttaaatcat gtagttatgt cgccatttaa atcggcaaac
    13501 ccacctgttt aaatttatg
//
LOCUS       DAJVKX010000122        13492 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.122, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000122 DAJVKX010000000
VERSION     DAJVKX010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13492
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.122"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..448)
                     /locus_tag="OPY25_003537"
     CDS             complement(<1..448)
                     /locus_tag="OPY25_003537"
                     /EC_number="2.7.7.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462116.1"
                     /note="catalyzes the ATP-dependent addition of AMP to a
                     subunit of glutamine synthetase; also catalyzes the
                     reverse reaction - deadenylation;
                     adenylation/deadenylation of glutamine synthetase subunits
                     is important for the regulation of this enzyme; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamine synthetase
                     adenylyltransferase/deadenyltransferase"
                     /protein_id="HCS0929050.1"
                     /translation="MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALD
                     SVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVCDDASLMRELRLFRRRIMVRIA
                     WAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQ"
     gene            complement(566..1867)
                     /locus_tag="OPY25_003538"
     CDS             complement(566..1867)
                     /locus_tag="OPY25_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HCS0929051.1"
                     /translation="MAQEIELKFIVNHDAVDALRNHLHTLGGEHHAPSQLLNIYFETP
                     DNWLRRHDMGLRIRGENGRYEMTMKIAGRVTGGLHQRPEYNVALSEPVLDLTQLPAEV
                     WPDGNLPDGLASSVQPLFSTDFYREKWCLDVDGSRIEIALDLGDVKAGEFAEPICELE
                     LELLRGDTRAVLKLAKQLLSQTGLRQGSLSKAARGYHLAQGNAPRENTPTAILRTAAK
                     ATVEQGLEASLDLALSQWQYHEELWLRGDESAKEHVLDAMGLVRHALMLFGGIVPRKA
                     SAHLRDLLTQAEATMTSAVSAVTAVYSTQTAMAKLALTEWLVTKAWQPFLDAKAQAKM
                     ADSFKRFADIHLSRHAAELKKVFGQPLGDKYRDQLPRLTRDIDSVLLLAGYYDAMVAQ
                     AWLENWQGLRHAIITGQRIEIEHFRNEAINQQPFWLHSGKR"
     gene            2109..2723
                     /locus_tag="OPY25_003539"
     CDS             2109..2723
                     /locus_tag="OPY25_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCS0929052.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDNY
                     RLVGTVNAGEEVTLLQSDANYGQIKDSSGRTAWIPLKELNTTPSLRTRVPDLENQVKT
                     LTDKLNNIDTTWNQRTADMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVSAANLQL
                     DDKQRTIIMQWFMYGGGVLGIGLLLGLVLPHMIPSRKRKDRWMN"
     gene            2786..4027
                     /locus_tag="OPY25_003540"
     CDS             2786..4027
                     /locus_tag="OPY25_003540"
                     /EC_number="2.7.7.72"
                     /EC_number="3.1.3.-"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional CCA addition/repair protein"
                     /protein_id="HCS0929053.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEADLQRRDLTINALARDD
                     DGQIIDPYHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLTLM
                     REMTAAGELEHLTPERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPA
                     PAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDVGKGLTPKNLWPRHHGHGPV
                     GVKLVEQLCQRLRVPNDLRDLAKLVAAYHDLIHTFPILQPKTIVKLFDAIDAWRKPQR
                     VEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIEIREEL
                     TKRRIAAVANWKEKRCPNPAS"
     gene            complement(4132..4953)
                     /gene="bacA"
                     /locus_tag="OPY25_003541"
     CDS             complement(4132..4953)
                     /gene="bacA"
                     /locus_tag="OPY25_003541"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCS0929054.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQREGESKGRLTLIHILLGMIPA
                     VVLGLVFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATVLDLYKSWSF
                     LTAADIPMFAVGFVTAFVVALIAIKTFLQLIKRISFIPFAIYRFVVAAAVYVVFF"
     gene            complement(5051..5410)
                     /gene="folB"
                     /locus_tag="OPY25_003542"
     CDS             complement(5051..5410)
                     /gene="folB"
                     /locus_tag="OPY25_003542"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HCS0929055.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKSAKS
                     DDVADCLSYADIADTVINHVEGGRFALVERVAEEVADLLLSRFNSPWVRIKLSKPSAV
                     ARAANVGVIIERGNNLK"
     gene            5517..6128
                     /gene="plsY"
                     /locus_tag="OPY25_003543"
     CDS             5517..6128
                     /gene="plsY"
                     /locus_tag="OPY25_003543"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCS0929056.1"
                     /translation="MSAIAPGMILFAYLCGSISSAILVCRIAGLPDPRESGSGNPGAT
                     NVLRIGGKGAAVAVLIFDILKGMLPVWGAYALGVTPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKLKKKRQKD"
     gene            6127..6255
                     /locus_tag="OPY25_003544"
                     /pseudo
     CDS             6127..6255
                     /locus_tag="OPY25_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311971.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
     gene            6257..6337
                     /locus_tag="OPY25_003545"
                     /pseudo
     CDS             6257..6337
                     /locus_tag="OPY25_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:sulfate symporter"
     gene            complement(6378..7391)
                     /gene="tsaD"
                     /locus_tag="OPY25_003546"
     CDS             complement(6378..7391)
                     /gene="tsaD"
                     /locus_tag="OPY25_003546"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCS0929057.1"
                     /translation="MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQAALKEAALTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     NVPAIPVHHMEGHLLAPMLEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRSNGDDEQTRADIARAFEDAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLR
                     AKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAEL
                     PAA"
     gene            7619..7834
                     /gene="rpsU"
                     /locus_tag="OPY25_003547"
     CDS             7619..7834
                     /gene="rpsU"
                     /locus_tag="OPY25_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCS0929058.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            8070..9815
                     /gene="dnaG"
                     /locus_tag="OPY25_003548"
     CDS             8070..9815
                     /gene="dnaG"
                     /locus_tag="OPY25_003548"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCS0929059.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDVRVKLKKQGKNYHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEIPYEAG
                     TGLSQIERHQRQNLYQLMNGLNDFYQQSLTHPAAKPARDYLQKRGLSAEIIQRFAIGF
                     APPGWDNALKRFGNNSDNKALLLDAGMLVNNEQGSTYDRFRNRVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQYSAEPQRLLVVEGYMDVVALAQY
                     DINYAVASLGTSTTADHMHMLFRATNNVICCYDGDRAGRDAAWRALETAMPYMTDGRQ
                     VRFMFLPDGEDPDTLVRKEGKAAFEARMEQAQPLSTFLFNSLLPQVDLSSPDGSTQLA
                     ALALPLINQVPGDTHRIQLRQTLGLKLGIFDDSQLDRLVPKQAESGVSRPAPQLKRTT
                     MRILIGLLVQNPDLAPLVPPLDALDQNKLPGLGLFKELVKTCLAQPGLTTGQLLELYR
                     GTNDAATLEKLSMWDDIADKAIAEKTFTDSLNHMFDSLLQLRQEELIARDRTHGLSSE
                     ERRELWTLNQELARK"
     gene            9965..11812
                     /gene="rpoD"
                     /locus_tag="OPY25_003549"
     CDS             9965..11812
                     /gene="rpoD"
                     /locus_tag="OPY25_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCS0929060.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLLLAENTTSTDEDAEEAAAQVLSSVESEIGRTTDPVRM
                     YMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARL
                     SDLITGFVDPNAEEEMAPTATHVGSELSQEDLDDDEDEDEEDGDDDAADDDNSIDPEL
                     AREKFAELRAQYVVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMR
                     VMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSETWFNAAIAMNKPWSEKLHD
                     VAEEVQRCLQKLRQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISI
                     AKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQAR
                     TIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPIS
                     METPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFG
                     IDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(11936..12442)
                     /gene="mug"
                     /locus_tag="OPY25_003550"
     CDS             complement(11936..12442)
                     /gene="mug"
                     /locus_tag="OPY25_003550"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HCS0929061.1"
                     /translation="MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLA
                     GFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPA
                     ALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELD
                     QALIMRGL"
     gene            12568..12643
                     /locus_tag="OPY25_003551"
     tRNA            12568..12643
                     /locus_tag="OPY25_003551"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12601..12603,aa:Ile,seq:cat)
     gene            complement(12723..13490)
                     /locus_tag="OPY25_003552"
     CDS             complement(12723..13490)
                     /locus_tag="OPY25_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-interacting protein"
                     /protein_id="HCS0929062.1"
                     /translation="MTTSSARYPQRVRNELRFRELTVLRVERISAGFQRIVLGGEALD
                     GFTSLGFDDHTKVFFPEPGCRFTPPTVTEEGIIWGEGVRPVSRDYTPLYDEAHRELAL
                     DFFIHDGGVASRWAMEAREGDTLTIGGPRGSLVVPEDYACQVYVCDESGMPALRRRLE
                     SLSRLPARPAVTALVSIQDAAYRDYLAHLTDITVEYVVGGDEQAMQTRLSQLAIPESD
                     YFIWITGEGKTVKRLSQCFEKGFDPHLVRAAAYWHRK"
BASE COUNT         3287 a         3743 c         3487 g         2975 t
ORIGIN      
        1 cctgcgggtt acagggggtt ccccattcgc ggcaacaggc ggcatacagc cagtcgcgcg
       61 ccccgacgat gagcgtctcc gccagatggc tcaactgttg taaaatagtc tcatcgtcca
      121 ccagcgacag cgtctgtgcc caggcgatgc gtaccatgat gcgacgacga aaaagcctca
      181 gctcacgcat cagcgaggcg tcgtcacaga cacctgccaa cgcctcctgt aaccagccag
      241 cgtaatgtcg ccattcatca gcctgcggcg atgcggattc cagttcggca agccactccg
      301 gatgcgctat cacgctatcc agcgcaaaat cgctaaatgt aagcactgac ttcgcctgcg
      361 cgctaagcga tgtctcagta aatccttctg gtaggcgctc aacaacggtc tgccagtact
      421 gcgataaggg tgaagagagc ggcgtcattt aggggatatc ctttaaataa tgccggatgg
      481 cggcgtttcg cctgatccgg cctacaagtc cgcataccgt aagcctgata agcgcagcgt
      541 catcaggcgc tttctacggt tctgattatc gttttccgct gtgcaaccag aacggctgct
      601 ggttgatggc ctcattacgg aaatgttcaa tttcaatacg ttgcccggta ataatggcgt
      661 gacgcaatcc ctgccagttt tccagccatg cctgcgcgac catcgcatca taatacccgg
      721 ccagcagtaa aacgctgtcg atatcgcgag tcaaacgcgg caactggtcg cgatacttat
      781 cacccagcgg ttgtccaaaa acttttttta attcagcagc atgacgagaa agatgaatgt
      841 cggcgaaacg cttaaaagaa tcggccattt tggcctgcgc cttcgcgtcc agaaatggct
      901 gccaggcttt cgtcaccagc cattccgtca atgccagttt cgccatcgcc gtttgcgtac
      961 tataaacggc tgtgacggcg gacaccgcgg atgtcatcgt cgcttccgcc tgggtaagta
     1021 gatcacgtaa gtgagcgctc gctttacgtg gaacaatgcc accaaaaagc attaaggcat
     1081 ggcgcactaa tcccatagca tccagcacat gttctttcgc cgactcgtcg ccgcgcagcc
     1141 agagctcttc atggtactgc cactgtgaca acgccagatc cagcgaggcc tccagccctt
     1201 gctctaccgt agctttcgcg gcagtccgca gaattgccgt tggtgtattc tctcgcggcg
     1261 cattcccctg cgccaggtga taacctcgcg ccgccttact cagactgccc tgacgcaaac
     1321 cggtttgcga cagcagttgc ttcgccagtt ttaacacggc gcgcgtatcg ccgcgaagca
     1381 actcaagctc cagctcacaa attggttcgg caaactcgcc cgcttttacg tcgccgagat
     1441 cgagcgcaat ttcaatcctg ctgccgtcaa cgtccagaca ccatttttcc cggtaaaaat
     1501 cggtactgaa cagcggctgt acgcttgatg ccaggccgtc gggcaggttg ccatccggcc
     1561 agacctccgc cggaagttgc gtcagatcca gcacgggttc gcttagcgca acattgtatt
     1621 cgggtcgctg gtgcagcccg cccgttaccc ggccggcaat tttcatggtc atttcatagc
     1681 gcccattttc accacgaata cgcagcccca tatcatggcg gcgtagccag ttatcaggcg
     1741 tttcgaaata gatattcagc aactggctgg gcgcatgatg ctcgccgccg agcgtatgaa
     1801 gatgatttcg cagcgcatct acggcgtcgt gattgacgat aaactttaat tcgatttcct
     1861 gagccatggc cttgtactta tgggttatgt cacatctggg aagattcttg gcgaacttac
     1921 ccgcattatt tttgtcagta gatagtattt tgcgccaaat tgccatgcaa cgagcaattt
     1981 gacgggcgta aaagtttgac gtagcggcaa aggcgacaca gatgattccg attgatgtcg
     2041 actgctttgc gtagcgacac tgatgccgtt actatcgttc cactttctct gacaataacg
     2101 acagcctgat gccaaaatta cgcctgattg gactaacttt acttgcgctt agcgccaccg
     2161 ccgtctctca tgctgaagag acgcgttacg tttctgatga actgaatacc tgggtccgca
     2221 gcggtccggg agataattat cgccttgtgg gtaccgtcaa cgccggcgag gaagtcacgc
     2281 tcttacagag cgatgccaac tatggtcaaa ttaaagacag ttctggtcgt actgcctgga
     2341 taccgttaaa agaactgaat accacgccaa gcctgcgtac ccgcgtgccg gatctggaaa
     2401 atcaggtcaa aacgttaacc gataaactca acaatattga taccacgtgg aatcagcgca
     2461 ccgccgacat gcagcagaaa gtggcgcaaa gcgacagcgt catcaacggg ctaaaagaag
     2521 agaaccagaa gctgaaaaac gagctgattg tcgcgcagaa aaaagttagc gccgcgaatc
     2581 tgcaactgga tgacaaacag cgcaccatta ttatgcagtg gtttatgtat ggcggcggcg
     2641 tattgggtat tggcttgctg ttagggctgg tgctgccgca tatgatccca agccgtaaac
     2701 gcaaagaccg ctggatgaac taaatcgcct tctctgcggc actgtcttat cattagagga
     2761 tgatcgtttt taaaaggaaa gtggcgtgaa gatttatctg gtcggtggtg cggttcggga
     2821 tgcgttgtta gggctaccgg ttaaagataa agattgggtc gttgtcggcg ccacgccgca
     2881 ggagatgctt gatgcgggct accagcaggt aggccgtgat tttcctgtgt ttctccaccc
     2941 gcaaactcac gaagaatacg cgctggcgcg taccgagcgt aaatccggtt ccggctacac
     3001 gggtttcacc tgctatgccg cgccggacgt taccctggaa gccgacctcc agcgtcgcga
     3061 tctgaccatt aatgctctgg cgcgcgacga tgacggacag attatcgacc cttaccacgg
     3121 gcgccgggat ctggaggcgc gtctactgcg ccatgtctct ccggcgtttg gcgaagatcc
     3181 cttgcgcgta ttgcgcgtgg cgcgttttgc cgcccgttac gctcatctta gtttccgtat
     3241 cgccgatgaa acactgacgc taatgcgcga aatgaccgcg gcaggcgagc tggaacatct
     3301 gacgccggaa cgggtatgga aagagacgga aaatgcgctt accacccgca atccgcaggt
     3361 ttacttccag gtattgcgcg actgcggcgc cctgcgcgtc ctgtttccgg aaatcgacgc
     3421 cctgtttggc gtacccgcgc cggcaaagtg gcatccggaa attgataccg gagttcatac
     3481 gttgatgacg ctgtcgatgg ccgccatgct cagtccgcag cttgatgtcc gtttcgccac
     3541 gctttgtcat gatgtgggca aaggcttaac gccgaaaaac ctctggccgc gccatcatgg
     3601 ccacggcccg gtgggcgtga aactggtcga acagttatgc cagcgtttgc gcgtccccaa
     3661 tgacctgcgt gatttagcta aactggtcgc cgcgtaccac gatctgattc acacctttcc
     3721 gatactccag ccgaaaacga tcgttaagct gtttgacgcc attgatgcat ggcgtaaacc
     3781 gcagcgcgtc gagcagattg cgctgaccag cgaggccgat gtccgtggac gtaccggctt
     3841 tgaagcgtcg gattacccgc aggggcgctg gctgcgcgaa gcctggcagg tggcccaagc
     3901 ggtaccaacg aaagaggtgg tggaggccgg atttaagggc attgagattc gcgaggagct
     3961 gacgaagcga cgaattgcag cggtcgccaa ctggaaagag aagcgctgcc cgaaccccgc
     4021 cagctaaacg ccatccggca cgataaattg cctgatggcg ctgcgcttat cagaccgaca
     4081 aaactgttag gccggacaag gcggtacgcc gccatccggc acggtcaatc atcagaagaa
     4141 gacaacgtaa acggcagccg ccaccacaaa gcggtaaatc gcaaacggaa taaacgagat
     4201 acgcttaatc agttgcagga aggtcttgat ggcgatcagc gccaccacaa acgccgtcac
     4261 aaagcccacc gcgaacattg gaatatccgc tgcggtcagg aatgaccaac ttttgtagag
     4321 atccagaacc gttgcgccca tcatcatcgg cacagccagt aagaacgaga actcggaggc
     4381 ggcgtaacgg ctgacgccca tcagcatccc accggaaatg gtcgctccgg aacgcgagaa
     4441 gcccggccac agcgccagac actggaaaca gccaatcata aacgcctgac gatacgtcat
     4501 atcatccagc cccggcgcgc gcggttcttt cggcttcagg cactcggcgg caatcagcaa
     4561 cagaccgcct accaccagcg catacatcac gttaatcggg ttaaatagcg acttgatcgt
     4621 gtcatgaaag actaacccca gcaccaccgc cggaatcatg cccagcagga tgtgaatcaa
     4681 cgttaatcga cctttacttt caccttcacg ctgtagcggg cggccaaagt gaataccgat
     4741 gagaccaaac aaccgccgcc agaacatcac cacgaccgcc agaatagatc caagttgaat
     4801 caccacttcg aatgtcttgg ccgtatcgcc ttcaaacccc agcagatgac ccacaataat
     4861 catatggccc gtgctggata ccggcaaaaa ctccgtcaat ccttcgacca cacccaaaat
     4921 tgccgctatc agcagcgagt gcatatcgct catcaataaa cccctaaaat gaaaaacact
     4981 gcaaaaatgg atctcgcgtt aagaccccat atataaccgt ttggtttaaa aaatataaaa
     5041 ttatttattt ttatttcaga ttattgccac gctcaataat tacccctacg ttcgccgcgc
     5101 gcgcgacggc gctaggcttg ctcagtttga tgcgaaccca cggagaattg aatcggctaa
     5161 gcagtagatc cgccacctct tccgccacac gctcgaccag agcaaaacgc ccgccttcaa
     5221 catgatttat caccgtgtcg gcgatatccg cgtaacttag acaatctgcg acatcatcgc
     5281 ttttcgccga cttgcggtta tcccatgcca tttcgatatc gaacaccagt ttttgctcga
     5341 tagtctgttc ccagtcgtaa acaccgatag tggtgattac cgaaagttgc tctataaata
     5401 caatatccat cacgacctgc ctgctttttg gctaacccgg ataccacttc cggcgaaatg
     5461 tgcgtattat ccacagaaat agtaaataaa acgacacttt caatacggaa cagcttatga
     5521 gtgcaatcgc gcctggaatg atcctcttcg cgtacctctg cggctcaatt tccagtgcca
     5581 ttctggtttg ccgcatcgcc gggctgcccg atccgcgaga aagcggctcc ggcaacccgg
     5641 gcgcgacgaa cgtattacga atcggtggca agggagcggc tgtcgcggta cttatttttg
     5701 acatccttaa aggcatgttg cccgtctggg gcgcgtatgc gttaggcgtt acccctttct
     5761 ggctggggct tatcgctatc gccgcctgtc tgggacatat ctggccggtc ttttttggct
     5821 ttaaaggcgg gaaaggcgta gcaaccgcgt ttggcgccat tgcgcccatc ggctgggatt
     5881 taaccggcgt catggcaggc acctggctgc tgacggtcct gttaagcggt tattcatcgt
     5941 taggggcgat tgtcagcgcc ttgattgcgc cgttttacgt ctggtggttt aaaccgcagt
     6001 tcactttccc ggtgtcgatg ctgtcatgtc tcattttgct gcgccatcat gacaacatcc
     6061 agcgtctgtg gcgtcgccag gagacgaaaa tctggacgaa gctgaaaaag aaacgccaga
     6121 aagattgagc tggaactgcg tctggaagag ggcctcaacc gtctggggat cggcccacaa
     6181 gggttgaccg gcaatagctc ggtgataggc gtacatatcg aatccgccgc gcgtcaccct
     6241 tccaccattg gcgtggttag gcgcgatttt cggcctgatt ttcctggtgc tgctgatcgt
     6301 ctccaggctg ttgtggatgc ccatcgtttt gctgtaaatc cgttggggcg gcatgatgtc
     6361 gccccctttt tccgctttta cgccgccggc agctcggcca gcggccagcg cggacgtacc
     6421 gttacgccaa gatccgccgt aacgcccgcc ttaaaccgca ccattccggc ataggcgatc
     6481 atcgccccgt tgtcggtaca aaattccggg cgcgcataga acacttcgcc gcggcgtttt
     6541 tgcatcattt cggcaagctt cgcacgcagc gtgcggttag cgctgacgcc gcccgccatg
     6601 acaagacgct taaaaccggt gctttccagc gcgcgcttgc acttgatcat cagcgtatcc
     6661 acgaccgcat cttcaaaagc gcgcgcgata tcagcgcgag tttgttcgtc gtcgccatta
     6721 ctacgaatgg tgttagcggc aaaggttttc agaccggaaa aactaaaatc cagccccggg
     6781 cgatcggtca tcgggcgcgg aaagacaaaa cgccccgccg tcccctgcga cgccattttc
     6841 gacagcatcg ggccgccagg ataatccagc cccaacaatt tggcggtttt atcaaacgct
     6901 tcaccggcgg catcgtcaat cgactctccc agcagttcgt actgaccgat tccggtcacg
     6961 ctaatgagct gcgtatgtcc gccggagacc agcagcgcca caaacgggaa atccggaggg
     7021 ttatcttcca gcattggcgc cagcagatga ccttccatat ggtgtacagg aatggctggc
     7081 acattccagg caaatgccag cgaacgcccg acggttgcgc cgaccagcag cgcgccgacc
     7141 aagcccgggc ctgcggtata ggccaccgcg tcgatatcgc tcgccgtcag agcggcttct
     7201 tttaatgccg cctgaatcag cggcacggtt ttacgcacat gatcgcggga agccagttca
     7261 ggcactacgc cgccgtaatc agcatgtaat ttcacctgac tatacaattg gttggctaac
     7321 agaccttttt tgtcgtcgta aatagcgatg ccggtttcat cgcaagatgt ttcaataccc
     7381 agtacacgca tgacttgttt tacctcgctc taataccgcg cagtgtaggt cgaatgcggg
     7441 tggatgtata ccctcagtcc cgacttcgtg tatactccct ccccttataa aagtcccttt
     7501 caaaaaaggc cgcggtgctt tacaaagcag cagcaattgc agtaaaattc cgcaccattt
     7561 tgaaataagc tggcgttgat gccagcggca aaccgaatta atcaaaggtg agaggcacat
     7621 gccggtaatt aaagtacgtg aaaacgagcc gttcgacgta gctctgcgtc gcttcaagcg
     7681 ttcctgcgaa aaagcaggtg ttctggcgga agttcgtcgt cgtgagttct atgaaaaacc
     7741 gacgaccgaa cgtaagcgcg ctaaagcttc tgcagtgaaa cgtcacgcga agaaactggc
     7801 tcgcgaaaac gcacgccgta ctcgtctgta ctaatctttt gagagcgggc tgctctcaat
     7861 tcagatcgag ttgtagttgt aaggccgtgc ttccgaaagg aatgcgcggc ttgttttcgt
     7921 ttatgcatta gcatatacac aaaatcattc atgctacgtc caggcggcaa gagagcaagt
     7981 ccccggcgct tacgcaagtc agcgacaggg gtgagcaaac gtagccaaca ctacggcagc
     8041 ctgaagaatg acgtgtataa aaggggcata tggctggacg aatcccacgc gtatttatta
     8101 atgacctgct ggcgagaacc gatatcgtcg atctgatcga cgtgcgcgta aaactcaaga
     8161 aacagggcaa gaactatcac gcgtgttgtc cattccataa tgagaaaacc ccttctttca
     8221 ccgtaaacgg tgaaaaacag ttttatcact gctttggatg cggcgcgcat ggcaatgcga
     8281 tcgacttttt gatgaattac gacaagctcg aatttgtcga aaccgtcgaa gaattagcgg
     8341 ccatgcataa cctggaaatt ccctatgaag caggcaccgg gcttagccag atagagcgcc
     8401 atcaacggca aaacctctat cagttgatga atggtctgaa tgacttttat cagcagtcgc
     8461 ttacccatcc tgcggcaaaa cctgcgcgtg actatctgca aaagcgcggt ctgagcgctg
     8521 aaattattca gcgtttcgcc attggcttcg cgccgcctgg ttgggataac gcgttaaagc
     8581 gcttcggtaa taacagcgat aacaaggcat tgttgctgga tgccggaatg ctggtcaata
     8641 acgagcaggg cagcacttac gatcgtttcc gtaatcgggt catgttccct attcgggaca
     8701 aacgcggcag ggtgattggt tttggcggtc gagttctggg gaacgacacg ccgaaatacc
     8761 ttaactctcc ggaaacggac attttccata aaggccgcca gctatatggt ctttatgagg
     8821 ctcagcaata tagtgctgaa ccgcaacgct tgcttgtggt cgaaggttat atggatgtcg
     8881 tcgcactagc gcaatacgac attaactatg cggtcgcctc gctgggtacc tcaaccacgg
     8941 cagaccatat gcatatgtta ttccgggcga cgaacaacgt aatttgctgt tacgacggcg
     9001 accgggctgg ccgtgatgcc gcctggagag cgctggaaac agcaatgcct tatatgaccg
     9061 acggtcggca ggtacgcttt atgtttttac ctgacggcga agacccggat acgctggtgc
     9121 gtaaagaagg caaggcggct tttgaagcgc ggatggagca ggcgcagccg ctctctacgt
     9181 ttctgtttaa tagcctcctg ccgcaggtgg atttaagctc gccggatggc agcacgcagt
     9241 tagccgcgct ggcgctgccg ctcattaatc aggtgcctgg cgacacgcac cgtattcagc
     9301 tgcgccagac gttggggctg aagttaggca ttttcgatga tagtcagctt gatcgtttag
     9361 tgccaaaaca ggcggaaagc ggcgtttccc gcccggctcc gcagctaaaa cgcacgacca
     9421 tgcgtatact gataggatta ctggtgcaaa atccggatct cgcgccgtta gtgccgccct
     9481 tagacgcgct ggatcagaat aagctgcctg gacttggctt atttaaagaa ttggtcaaaa
     9541 cttgtttggc tcagccaggt cttactaccg gacaacttct ggaactctac cgtggcacaa
     9601 atgatgctgc gacccttgaa aaattatcga tgtgggacga tatagcagat aaggcgattg
     9661 ccgaaaagac ctttaccgac tcactcaacc atatgtttga ttcgctgctg caactgcgac
     9721 aagaagagct gatcgctcgc gatcgcactc acggtttaag cagcgaagaa cgccgagagc
     9781 tctggacgtt aaaccaggag ctggccagaa aatgaattta acggcttaaa tgccgcatat
     9841 cgttcgggaa gcccccgaca gccgcagtga gaggcagcgg ccaaaatata agtatgccct
     9901 cgctttaaat gtcgacagct ataccgtcga caccaatcaa acgaataagt gtggataccg
     9961 tcttatggag caaaacccgc agtcacagct gaaacttctt gtcacccgtg gtaaggagca
    10021 aggctatctg acctatgctg aggtcaatga ccatctgccg gaagatatcg tcgattcaga
    10081 tcaaattgaa gatatcatcc aaatgatcaa cgacatgggt attcaggtaa tggaagaagc
    10141 gcctgatgcc gatgatctgc tgctggctga aaataccacc agcaccgatg aagatgcgga
    10201 agaagctgct gcacaagttc tgtccagtgt tgagtctgaa atcggtcgta cgactgaccc
    10261 ggtacgcatg tatatgcgtg aaatgggcac tgttgaactg ttgacccggg aaggcgaaat
    10321 cgacatcgct aaacgtatcg aagacgggat caaccaggtt caatgctccg ttgccgaata
    10381 cccggaagcc attacctatc tgctggaaca gtacgatcgc gttgaggctg aagaggctcg
    10441 tttgtccgat cttatcaccg gctttgtcga tccgaacgcg gaagaagaga tggcgccgac
    10501 cgcaactcac gtcggttctg aactctccca ggaagacctg gatgatgacg aagacgaaga
    10561 tgaagaagac ggcgacgatg acgccgccga tgacgacaac agcattgacc ctgaactggc
    10621 acgcgaaaaa ttcgctgaac tgcgcgcgca atacgtcgtt acgcgcgaca ccatcaaagc
    10681 gaaaggccgc agccatgctg ccgcgcagga agagattctg aagctgtctg aagtgttcaa
    10741 acagttccgt ctggtaccga agcaattcga ctatctggtc aacagtatgc gcgtgatgat
    10801 ggatcgcgtg cgtactcagg aacgtctgat catgaagctc tgcgtcgagc agtgcaaaat
    10861 gccgaagaag aactttatca cgctgtttac cggtaacgaa accagcgaaa cctggttcaa
    10921 tgccgctatc gcgatgaaca aaccgtggtc ggaaaaactg cacgatgtcg cggaagaagt
    10981 gcaacgctgc ctgcaaaaac tgcggcagat agaagaagag accggtctga ccatcgaaca
    11041 ggtgaaagac atcaaccgtc gcatgtccat cggggaagcg aaagcccgcc gtgcgaaaaa
    11101 agagatggtt gaagcgaact tgcgtctggt tatttctatc gccaagaaat acaccaaccg
    11161 aggtctgcag ttcctcgatc tgattcagga aggcaacatc ggtctgatga aagcggtaga
    11221 taagttcgaa taccgtcgtg gttacaagtt ctccacctac gctacctggt ggattcgtca
    11281 ggcgatcacc cgctctatcg ccgaccaggc gcgcaccatc cgtattccgg tgcatatgat
    11341 tgagaccatc aacaagctca accgtatttc tcgccagatg ctgcaagaga tgggccgcga
    11401 gccaacgccg gaagagctgg ctgaacggat gctgatgccg gaagataaaa ttcgtaaggt
    11461 gctgaaaatc gccaaagagc ctatctccat ggaaacgccg atcggcgacg atgaagattc
    11521 gcatctgggt gatttcatcg aggatactac cctcgagctg ccgctggact ctgccaccac
    11581 cgagagcctg cgcgccgcca ctcacgacgt tttggctggc ctgaccgctc gtgaagcgaa
    11641 agtcctgcgt atgcgtttcg gtatcgatat gaacaccgac cacacgctgg aagaagtggg
    11701 taaacagttc gacgttaccc gcgaacgtat ccgtcagatc gaagcgaagg cgctgcgtaa
    11761 actgcgccac cctagccgtt ctgaagtgct gcgcagcttc ctcgacgatt aattcgccgt
    11821 acacgtataa acgccgccgc aaggcggcgt ttttttatca ggtcatgcgc gagcgttcta
    11881 tttggcctgc agaatctcta cacaacgcga gtattcgcgc cctcattccc cattgctata
    11941 gcccacgcat aatgagcgct tgatccagct cgcgataggc ctcgaccagt ttttccgttt
    12001 taattcggtt taagccgctg ggattcggca acacccacac catcgtcgcg ccaatggcga
    12061 tcttttgttt accccaggcg ataccgcgct ggctgaatcc ctgttcaaaa gcctgtttac
    12121 caagcaccgc cagcgccgcg ggctggtagt cctctatctt ttcaatcagg ttgcgtccgc
    12181 cgctacgtaa ttcatgcaac ttcacctcag tcgcttgtac cgtcggtcgg tcgacgagtt
    12241 tcgttacccc gcagcgaaaa tccagtaatt tttccgcctc ctccggtttc aactgtcgat
    12301 cggtgaaacc ggccaaatga ataactttcc aaaaacgatt cgcgggatgc gcaaacggaa
    12361 agccggtatt cgccgaggag agtcccggat tgatgccgca aaaaaccacc cgtagccctg
    12421 gcgccagtat gtccttaacc attattactc ctgagcaata caacgttctt taagtataac
    12481 gggttgaaaa cacattgttt ataaaaacag cacccgcacg gttacggctg gattacagcg
    12541 taaagttaca ttataatcca ccgccacggc cccttagctc agtggttaga gcaggcgact
    12601 cataatcgct tggtcgctgg ttcaagtcca gcaggggcca ccaaatttta gctttaaaat
    12661 catataatta agccactcta aagagtggct tttttgtttc tgacagggct cgccccatac
    12721 cgctatttac gatgccaata ggctgccgca cgtaccaggt gtggatcaaa ccccttttca
    12781 aagcactgac ttaaacgttt taccgttttg ccttcgccag taatccagat gaaatagtct
    12841 gattctggta ttgccagctg cgacaggcgc gtttgcattg cctgttcatc gccgccaaca
    12901 acatattcca cagtaatatc cgtcaaatgg gcgagataat cgcgatatgc ggcatcctga
    12961 atgctcacca gcgcggttac cgcagggcgc gcaggcagac ggctaagcga ttccagacga
    13021 cgacgtagcg caggcatacc ggactcatcg cagacataaa cctgacaagc ataatcttcc
    13081 ggcaccacca gcgaaccgcg cggcccgcca atcgtcagtg tatcgccttc acgggcttcc
    13141 attgcccaac ggctggctac gccgccatcg tggataaaga aatccagcgc cagctcgcga
    13201 tgcgcctcgt catacagcgg cgtgtaatcc ctggagaccg gacgaacgcc ctccccccag
    13261 ataatgcctt cctcagtgac tgtcgggggc gtaaagcgac agcctggctc agggaaaaaa
    13321 actttcgtgt gatcgtcaaa gcccagggag gtgaaaccgt ccagcgcctc gccgccaagt
    13381 acgatccgct gaaatcctgc gctaatacgt tctacccgca gaacggtcag ctcgcgaaaa
    13441 cgcagttcat tacgaacacg ctgtggatag cgtgcggatg atgtcgtcat tt
//
LOCUS       DAJVKX010000123        13413 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.123, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000123 DAJVKX010000000
VERSION     DAJVKX010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13413
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.123"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(5..1060)
                     /locus_tag="OPY25_003553"
     CDS             complement(5..1060)
                     /locus_tag="OPY25_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HCS0929063.1"
                     /translation="MMSSNWVKNAINEINADHQRSADTHLIRLPLSAFPGIQLYLKDE
                     STHPTGSLKHRLARSLFLYGLCNGWIKEDTPIIEASSGSTAISEAWFARLLGLPFIAA
                     MPACTAKRKIEQIQFYGGHCHFVESACEIYAASERLAHELNGHYMDQFTYAERATDWR
                     GNNNIADSIFRQMRNEPHPVPRFIVMSAGTGGTSATIGRYIRCQGYDTQLMVVDPENS
                     VFLPYWQDRDASLRSPVGSKIEGIGRPRVEPSFIPDVVDEMLRVPDAASVATAHWLET
                     QLGRKVGASTGTNMWGALQLAARMREAGETGAIVTLLCDSGDRYLDTYYHPAWVSDHI
                     GDLTPWSAAIAKLLTGD"
     gene            1173..1631
                     /gene="decR"
                     /locus_tag="OPY25_003554"
     CDS             1173..1631
                     /gene="decR"
                     /locus_tag="OPY25_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HCS0929064.1"
                     /translation="MLDKIDRKLLCLLQQDCTLSLQALADAVNLTTTPCWKRLKRLED
                     DGILLGRVALLDPEKLGLGLTAFVLIKTQHHSSEWYCRFVTVVSEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDDFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            1672..3444
                     /locus_tag="OPY25_003555"
     CDS             1672..3444
                     /locus_tag="OPY25_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HCS0929065.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLMLIAMLQLIPPKVVGIVVD
                     GVTAQHFTPGRIAMWIGTIALIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYQRHRTGDLIARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIVMSTQISWQL
                     TLLALLPMPIMALMIKRYGDRLHDYFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSSLFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAISGGSWMVVNGSLTLGE
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVKDGEEPVPAGRGE
                     LTAAIREFCYPQTTHPALENVNFRLKPGQMLGICGPTGAGKSTILSLIQRHFDVTQGE
                     IRFHDMPLTHLQLDSWRSRLAVVSQTPFLFSDSIANNIALGRPEATQEEIERVARLAS
                     VHEDILRLPQGYDTQVGERGVMLSGGQKQRISIARALLLNAEILLLDDALSAVDGRTE
                     HQILHNLRQWGEGRTVIISAHRLSALTDANEIIVMQHGHVVQRGDHDQLAQQIGWYRD
                     MYRYQQLEAALDDAPERGEEAVNA"
     gene            3437..5218
                     /locus_tag="OPY25_003556"
     CDS             3437..5218
                     /locus_tag="OPY25_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HCS0929066.1"
                     /translation="MRSFGQLWPTLKRLLAYGSPWRKPLSVAVMMLWIAVAAEVSGPL
                     LISYFIDNMVARHHLPLGKVAGLAAAYVGLQFLAAGLHYAQSLLFNRAAVGVVQSLRT
                     DVMDAALRQPLSAFDTQPVGQLISRVTNDTEVIRDLYVTVVATVLRSAALIGAMLVAM
                     FSLDWRMALVAVLIFPAVLTVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSALILCGLLMLFSFTSA
                     GTIEVGVLYAFISYLSRLNEPLIELTTQQSMLQQAVVAGERVFELMDRPRQRYGSDDR
                     PLQSGAIDIDHLSFAYRDDNLVLQDITLSVPSRSFVALVGHTGSGKSTLASLLMGYYP
                     LTQGEIRLDGREIASLNHRVLRQGVAMVQQDPVVMADTFLANVTLGRDVSEAQVWQAL
                     ETVQLADLARGLSDGLHTHLGEQGNTLSVGQKQLLALARVLVDAPQILILDEATASID
                     SGTEQAIQQALAAIRERTTLVVIAHRLSTIVEADTILVLYRGQAVERGTHQQLLAAQG
                     RYWQMYQLQLVGEELAASVHEESGPTA"
     gene            5431..5769
                     /gene="glnK"
                     /locus_tag="OPY25_003557"
     CDS             5431..5769
                     /gene="glnK"
                     /locus_tag="OPY25_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCS0929067.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLEEVIDIISKAAYTGKIGDGKIFVAELMRVIRI
                     RTGEADEAAL"
     gene            5801..7087
                     /gene="amtB"
                     /locus_tag="OPY25_003558"
     CDS             5801..7087
                     /gene="amtB"
                     /locus_tag="OPY25_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HCS0929068.1"
                     /translation="MKIAMIKTTLASLALLPGLTIAAPAVADKADSAFMMICTALVLF
                     MTIPGIALFYGGLIRAKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNHFFGNADG
                     AMLKNIALTAVTGTIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWFTL
                     SYIPIAHMVWGGGLLAAHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGSANEIAALAFVNTVVATAAAILGWIIGEWTLRG
                     KPSLLGACSGAIAGLVGVTPACGYVGVGGALVIGVIAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCILTGVFAASSLGGVGFVDGVTMGHQVMVQLESIAITVVWSGVVA
                     FVGYKLADILVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(7187..8047)
                     /gene="tesB"
                     /locus_tag="OPY25_003559"
     CDS             complement(7187..8047)
                     /gene="tesB"
                     /locus_tag="OPY25_003559"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HCS0929069.1"
                     /translation="MSQTLNNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEARLVHSFHSYFLRPGDSQKPIIYDVEVLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEPGFEHQKTMPTAVGPEGLPSETEIAQSLAHLLPPILKEKFLCDRPLEI
                     RPVEFHNPLKGHVSAPVRQVWIRANGTVPDDIRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEKGIQIATIDHSMWFHRPFNFNEWLLYSVESTSASSARGFVRGEFYTQDGALVAST
                     VQEGVMRNHN"
     gene            8262..8831
                     /locus_tag="OPY25_003560"
     CDS             8262..8831
                     /locus_tag="OPY25_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HCS0929070.1"
                     /translation="MKLVHIVSGLAVAISLAACADKSADIQTPAPNPNMSITANQSTI
                     QQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLSQKAVRTEGKQAPFSFVL
                     PFNPSDIQPNARILLSAAITVDNKLVFITDSVKPVINNGGTKADLTLVPVQQTAVPVQ
                     ASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            complement(8864..9253)
                     /locus_tag="OPY25_003561"
     CDS             complement(8864..9253)
                     /locus_tag="OPY25_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HCS0929071.1"
                     /translation="MLVSCASGLSSPLIPDYPEALTQDSIMDIQDTFPQRVWQIVASI
                     PEGFVTTYGDVARLAGSPRAARQVGGVLKRLPEGSTLPWHRVVNRHGAISLTGPDLQR
                     QRQALLAEGVVVSGSGQIDLQRYRWVY"
     gene            9338..9434
                     /gene="ffs"
                     /locus_tag="OPY25_003562"
     ncRNA           9338..9434
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="OPY25_003562"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(9484..11034)
                     /locus_tag="OPY25_003563"
     CDS             complement(9484..11034)
                     /locus_tag="OPY25_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCS0929072.1"
                     /translation="MTTRHMVSLVTGVLILSVLFPIGLSLWLAHRQVEKRFNEELDIF
                     SSRVALRTERVSDQAKAALTHIASFKGEPCSSAHLLAMRRVSYSFRYVQEVLYLKNSI
                     PVCSSLEKESHIPAFPPPMKITRDGYRAWFTAQNDLGIKRYMAALGSDSYIVMIDPAS
                     FIDVIPFGAWPIDVAIIGRERNTVVASSGNLDHAILPLIHHETPLRLENRGIQYAIHP
                     FPEMGITIVSWAPTAPLERSWYRQAFIWLPAGIVTGLLAAAFILRILRRLQSPRHRLQ
                     DAIDNREINVHYQPIVSLSSGKIVGAEALARWQQADGTFLSPEIFIALAEQTGLTEPL
                     TRLIIDTVFEDMGSWLKSHPEQHISINLEASDLASETLPTLLSTLLNRSQISPSQIAL
                     ELTEREFADPKTSAPIVARYRNAGHSIYIDDFGTGYSSLSYLQNLDVDVLKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETTRQEQWLRQHGVHYGQGWLYSKPLPATAF
                     ILWVEQRL"
     gene            11259..11519
                     /locus_tag="OPY25_003564"
     CDS             11259..11519
                     /locus_tag="OPY25_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCS0929073.1"
                     /translation="MKPDIHPVYRTVVFHDTSANEYVKVGSTIKTEREIELDGVTYPY
                     VTIDVSSKSHPFYTGRQKTFDSESSAARFQKRFGHFIGAKRG"
     gene            11525..11665
                     /gene="ykgO"
                     /locus_tag="OPY25_003565"
     CDS             11525..11665
                     /gene="ykgO"
                     /locus_tag="OPY25_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HCS0929074.1"
                     /translation="MQVLNSLRNAKQRHPDCQIVKRKGRLYVICKTNPRFKAVQGRKK
                     RR"
     gene            complement(11721..12191)
                     /locus_tag="OPY25_003566"
     CDS             complement(11721..12191)
                     /locus_tag="OPY25_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929075.1"
                     /translation="MTEIQRLLSETIDDLNVREKRDNRPRFSISFIRKHPGLFIAMYA
                     AWFATLAVMLQSETLVGSVWLLVVLFIAFNGFFFFDIAPRYHYNDIDVLDLRVCYNGE
                     WYNTRFVPPTLIETILQSPQVDNEHKVQLQKMVARKGELSFYDIFTLARAEASR"
     gene            complement(12309..12860)
                     /gene="maa"
                     /locus_tag="OPY25_003567"
     CDS             complement(12309..12860)
                     /gene="maa"
                     /locus_tag="OPY25_003567"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HCS0929076.1"
                     /translation="MSDEKQKMIAGALYCPTDETLCQDRLRARQLIHQYNYTTPDEIN
                     KRQAILRDLLGRCEDAYIEPSFRCDYGYNIFLGHSFYANFDCVMLDVCPIHIGDNCML
                     APGVHIYTATHPLDAVERNSGRELGKPVTIGNNVWIGGRAVVNPGVTIGDNVVVASGA
                     VVTKNVPPDVVVGGNPARIIKKL"
     gene            complement(13039..13257)
                     /gene="hha"
                     /locus_tag="OPY25_003568"
     CDS             complement(13039..13257)
                     /gene="hha"
                     /locus_tag="OPY25_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HCS0929077.1"
                     /translation="MSDKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            complement(13285..>13413)
                     /locus_tag="OPY25_003569"
     CDS             complement(13285..>13413)
                     /locus_tag="OPY25_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity attenuator"
                     /protein_id="HCS0929078.1"
                     /translation="TFMLFSSYGINTQDLQKWRKSGNRLFRCFVNATRANPVSLSC"
BASE COUNT         3062 a         3313 c         3767 g         3271 t
ORIGIN      
        1 gtttctagtc gccggtaagt aattttgcga tggccgctga ccacggcgtc aaatcgccga
       61 tatggtcgct aacccaggcc ggatggtaat aggtatccag atagcgatcg ccgctatcgc
      121 acaataacgt cacgatagcg ccggtttctc cagcctcgcg catccgggcc gctagctgca
      181 gcgctcccca catattcgtg ccggtagagg cgccgacttt acggcctagc tgcgtttcca
      241 gccagtgtgc ggtggcaacg ctggcggcgt ccggcacgcg cagcatctca tccacgacat
      301 ccggaataaa agaaggctct actcgcggac gaccaattcc ttcaatttta ctgcctaccg
      361 ggctgcgtaa tgaagcgtcg cgatcctgcc agtaaggtaa aaagacagaa ttttccggat
      421 ccaccaccat gagctgagta tcatagccct ggcagcgaat atagcgccca atcgtcgcag
      481 aggttccgcc cgttccggcg ctcatgacga taaatcgcgg taccggatgg ggttcgttgc
      541 gcatctggcg gaaaatactg tcggcaatat tattgttgcc ccgccagtcg gtagctcgtt
      601 ctgcgtaggt aaactggtcc atatagtgac cgttcagttc atgcgccagc cgctcggagg
      661 cggcataaat ttcgcaggcg ctctccacaa aatgacagtg gccgccgtaa aattgaatct
      721 gttcgatttt acgttttgcg gtacaggcgg gcatggcggc gatgaacggc agtcccagta
      781 aacgcgcgaa ccaggcttcg gaaatcgccg ttgagcctga tgacgcttca ataatcggag
      841 tgtcttcttt aatccagcca ttgcacaacc cataaaggaa cagcgagcgc gccagacgat
      901 gcttgaggct accggtggga tgcgtgcttt cgtctttcag gtaaagctgg atacctggaa
      961 atgccgacag gggcaaacga ataagatgcg tatccgctga gcgctggtgg tcagcgttaa
     1021 tttcattaat ggcattttta acccaattgc tactcatcat taatatccat ttatcatttt
     1081 gtgccaagag tagcgaaaag tacggaaaaa attgttgcta tttgaccttt aaattacaat
     1141 gtaaggagaa aaatattctc tatggagtgg gtatgttaga taaaattgac cgtaaactgc
     1201 tttgcttatt gcagcaggac tgtaccctct ctttgcaggc gctggcggat gccgttaatc
     1261 tgacgacaac gccttgctgg aagcggctta aacgcctgga agatgacggt atcctgcttg
     1321 gcagggttgc gctgctggac ccggaaaaac tggggctggg gttaaccgct tttgtgttga
     1381 taaaaacgca gcaccacagc agtgaatggt actgtcggtt cgtgaccgtc gtctctgaga
     1441 tgccggaagt gcttggcttc tggcggatgg cgggggagta cgactatctg atgcgagttc
     1501 aggtggccga catgaagcgg tatgacgact tctataaacg tctggtcaat agcgtcccag
     1561 gactgtcaga cgtcacctcc agttttgcga tggaacagat taagtacacc acctctctgc
     1621 ccattgaata attctcccgg tattgccgga aatcatatca ggaaataacg cgtgcgatta
     1681 tttgctcaat taagctggta ctttcgccgg gaatggcgtc gctatcttgg cgcggtggcc
     1741 ctgcttatgc ttattgcgat gcttcagctg atcccgccca aagtggtggg gattgtcgtg
     1801 gatggcgtaa ccgcacagca ttttactcca ggccgaatag cgatgtggat tggcaccatt
     1861 gccctgatcg ccgtagtggt ctatttgttg cgctatgtct ggcgcgtgct gctatttggc
     1921 gcttcttatc aattagccgt cgaactgcgt gaagattatt atcgccagct gagtcgtcag
     1981 catcctgaat tttatcagcg ccatcgaacg ggcgatctta ttgcgcgtgc gacgaatgat
     2041 gtggatcgcg tcgtatttgc ggcgggcgag ggcgttctga cgctggttga ctcgctggta
     2101 atgggctgcg cggtactgat tgtcatgtcg acgcaaatta gctggcagct aacgctatta
     2161 gcgctgttgc cgatgccgat tatggcgctg atgatcaaac gttacggcga tcgactgcat
     2221 gattatttca aactggcgca ggccgccttc tccagcctga acgaccgcac gcaggagagt
     2281 ctgaccagca tccgcatgat caaagcgttt ggtctggagg accgccagtc ttcgctgttt
     2341 gcggcggatg ccgaagatac cggcaagaaa aatatgcgcg tggcgcgtat tgacgcgcgt
     2401 tttgatccaa ccatttacat cgccattggc atggcgaacc tgctcgcgat tagcggcgga
     2461 agctggatgg tggttaacgg cagcctgacg ctgggcgaac tcaccagctt tatgatgtat
     2521 ctggggttga tgatttggcc gatgctggcg ctggcctgga tgtttaatat cgtggagcgg
     2581 ggtagcgccg cttacagccg catccgcgcc atgctggcgg aagcgccggt agttaaggat
     2641 ggcgaagagc ccgtcccggc ggggcggggc gaactgacgg cggccattcg tgagttttgc
     2701 tatccgcaaa cgacgcatcc ggcgctggag aatgtgaact ttcgtcttaa accgggtcag
     2761 atgctgggga tatgcggtcc gaccggcgcg gggaaaagca caatcttgtc gcttatccag
     2821 cgccattttg atgtgacgca gggagagatc cgattccatg acatgccgtt gacgcatctg
     2881 caactggata gctggcgtag ccgactggcg gtcgtcagcc agacgccgtt tttgttctcg
     2941 gattctattg ccaataatat tgcgctcgga cgcccggagg cgacccagga agagattgaa
     3001 cgggtggcgc gtttagccag cgtacatgag gatattctcc gtttgcctca gggctatgac
     3061 acgcaggtag gtgaacgtgg cgtcatgtta tcgggtgggc aaaaacagcg tatctcgata
     3121 gccagagcgc tactgttgaa tgcggaaatt ctgcttcttg atgatgcgct ttcagcagta
     3181 gatggtcgta cggagcatca gattttgcat aatttgcgcc agtggggcga agggcgtacg
     3241 gtcatcatca gcgcgcatcg tttatccgcg ctgaccgacg ccaatgaaat tatcgttatg
     3301 caacatggtc atgttgttca gcgcggcgat cacgatcaac tggcgcagca gattggctgg
     3361 tatcgcgata tgtatcgcta tcagcaactg gaggccgctc tggatgacgc gccggaacgc
     3421 ggcgaggagg cggtgaatgc gtagttttgg acagctatgg ccgacgctga aacggttgct
     3481 ggcgtatggc tcgccatggc gaaaaccgct ctctgtcgcg gtgatgatgc tgtggattgc
     3541 ggtggcggcg gaggttagcg gtccgctgct gatcagctat ttcattgata acatggtggc
     3601 ccgccaccat ttaccgttgg gcaaggtcgc ggggctggcg gccgcctatg tggggctaca
     3661 gtttctggcg gcgggtctgc attacgccca gtctttatta tttaaccggg cggccgttgg
     3721 cgtggttcag tccttgcgca cggacgtcat ggatgccgcc ttgcgccagc cgctaagcgc
     3781 cttcgacacg cagcctgtcg gacaattaat ttcacgcgtg accaacgata cggaagtcat
     3841 ccgcgatctg tacgtcacgg tcgtcgcaac ggtattacgt agcgcggcgt tgatcggcgc
     3901 catgctggtc gccatgttca gccttgactg gcggatggcg ctggtggcgg ttttgatttt
     3961 tccggcggta ttgaccgtga tggtcattta tcagcgctac agcacgccga ttgtacgccg
     4021 cgtgcgggca tacctggcgg atattaacga cggctttaac gaaatcatca atgggatgag
     4081 cgtaattcag cagtttcgcc agcaggcgcg cttcggcgaa cgcatgggcg aggccagccg
     4141 ctcgcactac atggcgcgga tgcagacgct gcgcttggac ggctttttat tgcgtccgct
     4201 gcttagcctc ttttccgcgc tcattttatg cggtttgttg atgcttttca gctttacgtc
     4261 tgccggcacg attgaggtcg gggtgctgta tgcgttcatt agctatttgt cacgtctgaa
     4321 cgagccgctc attgaactga ccacccagca atccatgcta cagcaggcgg ttgtggcggg
     4381 agagcgtgtt tttgaactga tggatcgccc gcgccagcgc tatggcagcg acgacaggcc
     4441 gttacaaagc ggggcgattg atattgatca tctgtcgttt gcttaccgcg acgataatct
     4501 tgttttacag gacattacgc tatcagtacc gtcccgtagc tttgtggcgc tggtggggca
     4561 caccggcagc gggaagagca cgctcgccag cttattaatg gggtattacc ccctgacaca
     4621 aggcgaaatt cggctggatg ggcgagaaat cgcctctctt aatcatcgcg ttttacgcca
     4681 gggcgtggcg atggttcaac aggacccggt agtgatggcg gatacctttc tggctaatgt
     4741 gacgctgggg cgcgatgtct ccgaggcgca ggtgtggcag gcgctggaaa cggtacaact
     4801 ggcagatctg gcgcgcggcc tgagcgacgg gctgcatacg catctcggcg agcagggaaa
     4861 tacgctgtcc gtcgggcaaa aacagctatt ggcgctggcg cgcgtgctgg ttgacgcccc
     4921 gcaaatatta attcttgatg aagcgacggc cagcatcgat tccggcactg agcaggcgat
     4981 acagcaggcg ctggcggcga ttcgcgagcg caccacgttg gtggttattg cccatcggct
     5041 atcgacaatc gtggaggcgg ataccattct ggttctctat cgcggccagg cggtggagcg
     5101 cgggacgcat caacaattgc tggcggcgca agggcgctac tggcaaatgt atcaattaca
     5161 gttagttggc gaggagttag ccgccagcgt acacgaagaa tccggcccta cggcgtaagg
     5221 tttggcgcca cagggcaaaa cctcgcccat tatgcaccgt cgtggtgcgt ttttctttcc
     5281 ctgcttcgtt tttggggcgc gtcaatataa agacgcgccg ctaaccgcgc ttttcctcgc
     5341 tcgccagctt ctggcacatc ctttgcaata tccatcctga agagtccatg cgcggcggca
     5401 gccgttacct aattctgact ggagggttct atgaagctgg ttaccgtgat tatcaaaccg
     5461 ttcaagctgg aggacgtgcg ggaggcgctt tcttccattg gcattcaggg actgaccgtc
     5521 accgaagtga aagggtttgg ccgtcagaaa ggacacgccg aactgtatcg cggcgcggag
     5581 tacagcgtga atttcctgcc gaaggtcaaa attgatgtgg ctatcgccga cgaccaactg
     5641 gaagaggtga tcgatatcat cagtaaagcg gcttacaccg gaaaaattgg cgacggcaaa
     5701 attttcgtcg cggagctcat gcgcgttatt cggattcgta ccggcgaagc tgacgaagca
     5761 gcgctgtaag acccgccaca cagcaacagg aaatgaaaaa atgaagatag cgatgataaa
     5821 aaccacactg gcttcactgg cgctgctgcc tgggctaacg atagccgcgc cagcggttgc
     5881 cgataaagcg gatagtgctt ttatgatgat ttgcaccgcg ctggtgctgt tcatgacgat
     5941 accgggtatc gcgctgtttt acggcggatt aattcgcgcc aagaatgtgc tgtcaatgtt
     6001 aacgcaagtg accgtcacct ttgcgctggt ctgtatttta tgggtggtgt acggctattc
     6061 gctggctttt ggcgaaggga atcatttctt cggtaatgcc gatggggcga tgttgaagaa
     6121 tatcgcgttg acggcggtaa cgggtacgat ttatcagtat attcatgtcg cgtttcaggg
     6181 atctttcgcc tgtattaccg tcgggctgat tgtcggcgcg ctggcggagc gtattcgttt
     6241 ttcggcggta ctgatttttg tcgtggtgtg gttcacgctc tcttatatcc cgattgcgca
     6301 catggtgtgg ggcggcggcc tgctggctgc tcacggcgcg ctggattttg ccggtggtac
     6361 ggtggtgcat attaacgccg ctatcgccgg gctggtgggg gcttatttaa ttggcaaacg
     6421 cgtcggcttt gggaaagaag catttaaacc ccataacctg ccgatggtct ttaccggtac
     6481 tgcgattctg tatatcggct ggtttggatt taacgcgggt tctgcgggta gcgcaaacga
     6541 gatagcagcg ctggcctttg tgaacaccgt ggtggcgacc gccgccgcga ttctggggtg
     6601 gattatcggc gagtggacgc tacgcggtaa gccttccctg ctgggagcgt gttccggcgc
     6661 gattgccggt ctggtcggcg tgacgccagc ctgtggctat gttggcgttg gcggcgcgct
     6721 ggttatcggc gttattgcgg gtctggcggg attgtgggga gtcaccatgc ttaaacgtct
     6781 gctacgggta gatgatccgt gcgacgtatt tggcgttcac ggcgtttgcg gaatagtcgg
     6841 ctgtatcctg accggcgttt ttgccgccag ttcgctgggt ggcgtcggct ttgtcgacgg
     6901 cgttacgatg ggacatcagg tgatggtaca gctggaaagt attgctatta cggtcgtctg
     6961 gtccggcgtt gtcgcgtttg ttggttacaa actggcggat atccttgttg gactgcgtgt
     7021 accggaagag caggagcgcg aggggctgga tgtgaacagt cacggcgaga atgcgtataa
     7081 cgcgtgattg cgcaacatgc ctgatggcgc tgcgcttacc cagtctaccg taggccggat
     7141 aagcgcagcg tcatcaggcc attaacgccg catagcggca tgttttttaa ttgtgattac
     7201 gcattacccc ttcctgcacg gttgaagcga ccagcgcgcc atcctgagta taaaactcgc
     7261 cgcgaacaaa gccccgggcg ctggaggcgg aagtgctctc cacgctataa agtagccatt
     7321 cattaaaatt gaacggacga tggaaccaca tagagtgatc gatagtggcg atctgaatgc
     7381 ccttttccag aaaaccgatg ccgtgaggct gaagcgcgac gggaaggaaa ttcagatccg
     7441 aggcgtatcc cagtaaatat tgatggacgc gaatgtcatc cggaacggtg ccgttggcgc
     7501 gaatccatac ctgacgcaca ggcgcggaga cgtgaccttt caacggattg tgaaattcga
     7561 cgggacgaat ttccagcggg cgatcgcaga gaaacttttc tttcagaatc ggcggcagta
     7621 aatgcgccag cgattgcgcg atttccgttt ctgacggtag tccttccggc ccgactgccg
     7681 tcggcatggt tttttgatgt tcaaaacccg gttccggtgc ctggaatgag gcggtcatgt
     7741 aaaagatggg tttcccgttc tgaatagcgg caacgcggcg ggcgctgaag ctattcccat
     7801 cgcgcagcac ttctacgtca tagataatgg gtttttggct gtcgcctggc cgcagaaaat
     7861 aactgtggaa tgaatgcacc agtcgcgctt ccggcaccgt ttctttggcg gcatagagcg
     7921 cctggcccac cacctgaccg ccaaatacct ggcgcagccc taagtcttca ctttggcccc
     7981 gaaagagtcc ttcttcaatt ttttccagat tcaataatgt cagcaaatta ttcagtgtct
     8041 gactcataca tactctccag gtgacaacga tgccgaagcg aggtagggca gagtataacg
     8101 caattttgca agtggtccga tgggtacaaa agtctgaata acagaccaat tccaggcaaa
     8161 aatgagtgac atgtgccaca cttaatcacg ttgtatttct gttaaccact cttccggcgg
     8221 ggggaaaggc ctgctggtgc attgatgata aggagaattg aatgaaactc gtgcacatcg
     8281 taagtggttt agcggttgcg atatctctgg cggcctgcgc tgataaaagc gctgatatcc
     8341 agacgcctgc gccaaaccct aacatgtcga ttacagctaa ccagtctact attcagcaac
     8401 ccaatgtttc cggtaccgtc tggatccgcc agaaggtcgc tctgccgcca gatgcggtgc
     8461 tgaccgtgac gctttcagat gcttcgctgg ctgatgcgcc gtctaaggtg ctgtcgcaaa
     8521 aagcggtacg taccgaaggt aaacaggcgc ctttcagttt tgtgttgccg tttaacccat
     8581 cagatattca acctaacgcg cgtattcttc tgagcgcggc catcaccgtt gacaataagc
     8641 tggtatttat taccgatagc gtgaaaccgg tgattaacaa tggcggcact aaagcggatc
     8701 tgacgctggt accggtacag caaacggcgg tgcctgtgca ggccagcggc ggtgcgacga
     8761 cgacggttcc atcgacttcg ccgacccagg tcaatccgtc ttctgccgtt cctgcgccta
     8821 cccagtatta atcctgcgcc aaccctctcc gttacggaga gggttaatac acccagcgat
     8881 agcgttgtaa atcgatttgt ccgcttcccg acaccaccac gccttccgcc agtaatgcct
     8941 gacgttgccg ctgtagatcc ggcccggtaa gtgatattgc gccgtggcgg ttcaccaccc
     9001 gatgccatgg taaagtgctg ccttccggca gacgttttaa aactccgccg acctgacgcg
     9061 ccgcccgagg ggaaccggca agccgggcga catcaccgta ggtcgtgaca aacccttccg
     9121 ggatcgaggc gacgatttgc cagacgcgtt gaggaaatgt gtcctgaata tccataatag
     9181 aatcctgcgt taatgcttca ggataatctg gaataagggg ggaggaaagc ccggatgcgc
     9241 aagaaaccag catccgatgc ctgataggtt gcaattgcac gatatagcag tgataatgcg
     9301 cctgcgcgtt ggttcacaac gctctcaatg ggggctctgt tggttctccc gcaacgctac
     9361 tctgtttacc aggtcaggtc cggaaggaag cagccaaggc agatgacgcg tgtgccggga
     9421 tgtagctggc agggccccca cccaattctg cctttccaca ctgttctttt ctgctgtgcg
     9481 acgttatagc cgctgttcca cccaaagaat aaatgccgta gcgggtaggg gcttactgta
     9541 taaccagccc tgaccataat gtacgccatg ctggcgtagc cactgttctt gcctggtcgt
     9601 ttcgatgcct tctgcgacca tcttaagttt gagcgttttc gccatttcaa taatatgcgg
     9661 cgtgacgttt ttatattcca gcgcatcgac aaaagattta tcaattttaa ggacatccac
     9721 atccagattt tgtaagtagc tgaggctgga atagccggtg ccaaagtcat caatataaat
     9781 ggaatgtccc gcgttacggt atctggcgac aatgggcgcg ctggttttcg gatcggcgaa
     9841 ctcgcgctcc gttaactcaa gcgcgatttg cgacggagaa atttggctac ggttcagcag
     9901 cgtgcttaac agcgtcggga gcgtttccga cgccagatcg gatgcctcaa gattgattga
     9961 aatatgttgt tcgggatggg actttaacca actccccatg tcttcaaaaa cggtgtcgat
    10021 gattagccgg gttagcggct ccgtgagccc ggtttgttca gccagcgcga taaaaatttc
    10081 cggcgaaagg aaagtgccgt ccgcctgttg ccagcgagct aaggcttcgg caccgacaat
    10141 ttttccgctg ctcagggaga caataggctg atagtgtacg ttaatttcgc gattgtctat
    10201 cgcatcctgg agacggtggc ggggcgattg tagccgacgc aaaatacgca gaataaaggc
    10261 cgcagccagc agacccgtta cgatgcccgc cggtagccag ataaacgctt gtcgatacca
    10321 gctcctttcc agcggagcgg tcggtgccca gcttacgata gtaatgccca tttccggaaa
    10381 ggggtggata gcatactgaa tgcctcggtt ttccagccgc aggggcgtct catggtgaat
    10441 gagcggaaga atagcgtggt caaggttacc gctgctggca accacagtat tgcgttcccg
    10501 gccaataata gcgacgtcaa tcggccatgc gccaaacgga atcacatcga taaaggacgc
    10561 cgggtcgatc atcacgatat agctgtcgct cccgagtgcc gccatatagc gttttatacc
    10621 cagatcgttt tgcgccgtaa accaggcgcg ataaccgtcg cgagtgattt tcatgggcgg
    10681 agggaaagcg ggaatatggc tctctttttc aagtgaggag caaacgggaa tcgaattttt
    10741 aagatacaga acttcctgga cataccgaaa gctataagac acgcggcgca tggcgagtaa
    10801 atgggcgctg ctgcagggct cgcctttaaa ggaggcaata tgcgttaacg cggcttttgc
    10861 ctggtcactg accctttctg tacgtagcgc cacccgggac gagaagatat ccagctcttc
    10921 gttaaacctt ttttcaactt gacggtgcgc cagccacagg ctcaatccta tcgggaaaag
    10981 gacagacagg ataagcactc ccgttaccag gctgaccata tgtcgtgttg tcacagtgat
    11041 gtccttataa acacagcgta gagaaagtat atccgatcgt aaatcgcgcc ctcgaatgat
    11101 aaagctattt tatcgatttt acagatacag gggccagact aacgcgttac gccacgttgc
    11161 ttttgccgcc aggaagagat cgtgaatgtt taccggttga aaaaggagcg ttgatagcgt
    11221 attttattgt tatgttataa cataattgag agagcgcaat gaaacctgat attcatcctg
    11281 tataccgaac cgtcgtattt cacgacacca gcgcaaatga atatgtgaaa gtgggatcaa
    11341 ctatcaaaac tgaacgtgaa atcgaactgg acggcgtgac atatccgtat gtcactattg
    11401 atgtgtcatc aaaatcgcat cctttttata ccggtagaca gaaaacgttt gatagcgaaa
    11461 gtagcgccgc acgcttccag aaacgttttg gtcattttat cggcgctaaa cgggggtaaa
    11521 tgaaatgcag gtgttaaact cacttcgcaa tgcaaaacaa cggcatccgg attgccagat
    11581 agtcaaacgc aaaggacgct tatacgtgat ttgtaaaaca aatccgcgtt ttaaggcggt
    11641 tcaggggcgt aaaaaaagac gttaaaaaac caacagttca gggaaagcag tgcgtaccag
    11701 ggagggtgcg cactttttta ttaccggctg gcttctgcgc gggccagcgt aaaaatatcg
    11761 tagaaggaaa gttcgccctt acgggcaacc attttttgca gctggacttt atgttcatta
    11821 tccacctgtg gagactgaag aatcgtctca atgagcgtgg ggggaacaaa gcgggtgttg
    11881 taccattcgc cgttgtaaca gacccggagg tccagcacat cgatgtcgtt atagtgataa
    11941 cgcggggcga tgtcgaaaaa gaagaagcca ttaaatgcga taaataacac cactaacagc
    12001 cacactgacc ccaccagcgt ttctgattgc agcatgaccg ccagcgtcgc aaaccaggct
    12061 gcatacatcg cgataaataa cccaggatgc ttgcggataa aacttatact aaaacgcggc
    12121 ctgttatcgc gtttttcacg gacgtttaag tcatcaatag tttcgctaag caggcgctgt
    12181 atctctgtca tcttttgcct tcatgatttc tgcgacatag ggggtagtaa cagcccattt
    12241 taaagggagg tgtaacgtga aaaaagtaac agattaacca cgaattagca taacagttat
    12301 catttgaact acaatttttt aatgattcgc gccggatttc cgcctaccac gacgtctggc
    12361 ggtacgtttt ttgtcaccac agcgcctgaa gcgacgacga cgttatcgcc gatggttacg
    12421 ccaggattaa cgacggctcg tccgcctatc cagacgttat ttccgatagt gacgggttta
    12481 cctaattctc tgccgctgtt gcgttcgacg gcgtccagcg ggtgcgtggc ggtatagata
    12541 tgtacccctg gcgcgagcat acaattatcg ccaatatgaa ttgggcaaac atcaagcatg
    12601 acgcagtcga agttagcgta aaaggagtga ccaagaaaaa tattatagcc gtagtcgcaa
    12661 cggaaggaag gttcaatata ggcgtcttcg catcgaccca acaggtcgcg taaaatcgcc
    12721 tgacgcttat ttatttcatc aggcgtagta taattgtatt gatggatgag ttgacgcgcc
    12781 cgcagtcgat cctggcataa agtttcatcg gtcgggcaat acagtgcccc agcgatcatt
    12841 ttttgttttt cgtcactcat cgcgcgctcc ccttggtgga tattatcgca atagaagcaa
    12901 taataaagta ttagagggaa cgttccctgc tattggtatg tgatctatat cactgttcta
    12961 taatagcccg ttgtgttatt agccagaacg aggaggcaga taacacctgc gtgttctcta
    13021 aaaagtaatg tagcgtgatt aacgaatgaa tttccatact gaagagggga tcttgtcgta
    13081 gagtttgttc atcgtcaatt ctgcaagacg gtgatccgca gctgagtaaa atacagccag
    13141 ctcattgtcg gacaattcat atttattttt ctcaatgacg cgctccagag tgtcaattgt
    13201 ctgacagcgc cgtaaacgca tcaaataatc agttttagtt aatggtttat cagacataaa
    13261 ttctacctat gattgtaata atttttaaca agacaaacta acaggattag ccctggtggc
    13321 gttgacgaaa caacggaaca ggcggttgcc cgatttacgc catttttgca aatcctgcgt
    13381 attaatacca tagctgctga acaacataaa ggt
//
LOCUS       DAJVKX010000124        13022 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.124, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000124 DAJVKX010000000
VERSION     DAJVKX010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13022
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.124"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..372
                     /gene="tuf"
                     /locus_tag="OPY25_003570"
     CDS             <1..372
                     /gene="tuf"
                     /locus_tag="OPY25_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCS0929079.1"
                     /translation="GENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKD
                     EGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL
                     RFAIREGGRTVGAGVVAKVLG"
     gene            602..985
                     /gene="secE"
                     /locus_tag="OPY25_003571"
     CDS             602..985
                     /gene="secE"
                     /locus_tag="OPY25_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCS0929080.1"
                     /translation="MSANTEAQGSGRGLEAMKWIVVAILLIVAIVGNYLYRDMMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            987..1532
                     /gene="nusG"
                     /locus_tag="OPY25_003572"
     CDS             987..1532
                     /gene="nusG"
                     /locus_tag="OPY25_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCS0929081.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1690..2118
                     /gene="rplK"
                     /locus_tag="OPY25_003573"
     CDS             1690..2118
                     /gene="rplK"
                     /locus_tag="OPY25_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCS0929082.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            2122..2826
                     /gene="rplA"
                     /locus_tag="OPY25_003574"
     CDS             2122..2826
                     /gene="rplA"
                     /locus_tag="OPY25_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCS0929083.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASAN"
     gene            3242..3739
                     /gene="rplJ"
                     /locus_tag="OPY25_003575"
     CDS             3242..3739
                     /gene="rplJ"
                     /locus_tag="OPY25_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCS0929084.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3806..4171
                     /gene="rplL"
                     /locus_tag="OPY25_003576"
     CDS             3806..4171
                     /gene="rplL"
                     /locus_tag="OPY25_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCS0929085.1"
                     /translation="MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKSLEEAGAEVEVK"
     gene            4489..8517
                     /gene="rpoB"
                     /locus_tag="OPY25_003577"
     CDS             4489..8517
                     /gene="rpoB"
                     /locus_tag="OPY25_003577"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCS0929086.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     DEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8594..12817
                     /gene="rpoC"
                     /locus_tag="OPY25_003578"
     CDS             8594..12817
                     /gene="rpoC"
                     /locus_tag="OPY25_003578"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCS0929087.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECETLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERIYRAGLASLHARVKVRITEYEKDENGEFVAH
                     TSLKDTTVGRAILWMIVPKGLPFSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQT
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEQQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGILMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEANSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFIRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTTGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEIAGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIESAGSSDFLEGEQVEYSRVKIANRELEANGKVGATFSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEQ
                     PATPQVTAEDASASLAELLNAGLGGSDNE"
BASE COUNT         3165 a         3275 c         3616 g         2966 t
ORIGIN      
        1 ggtgagaacg taggtgttct gctgcgtggt atcaaacgtg aagaaatcga acgtggtcag
       61 gtactggcta agccgggcac catcaagccg cacactaagt tcgaatctga agtgtacatt
      121 ctgtccaaag atgaaggcgg ccgtcatact ccgttcttca aaggctaccg tccgcagttc
      181 tacttccgta ctactgacgt gactggtacc atcgaactgc cggaaggcgt agagatggta
      241 atgccgggcg acaatatcaa aatggttgtt accctgatcc acccgatcgc aatggacgac
      301 ggtctgcgtt tcgcaatccg tgaaggcggc cgtactgttg gcgcgggcgt tgttgctaaa
      361 gttctcggct aatcgctgat aacatttgac gcaatgcgca ataaaagggc atcatttgat
      421 gccctttttg cacgctttca caccagaacc tggctcatca gtgattttat ttgtcataat
      481 cattgctgag acaggctctg tagagggcgt ataatccgaa aggcgaataa gcgtttcgat
      541 ttggtttgcc tcgcgattgc ggggtgaaaa tgtttgtaga atacttctga caggttggtt
      601 tatgagtgcg aataccgaag ctcaagggag cgggcgcggc ctggaagcga tgaagtggat
      661 agttgttgcc atattgctga tcgtcgcaat cgtcggcaac tacctctatc gcgacatgat
      721 gctgccgctg cgtgcgctgg ccgtagtaat tctgattgct gcagcgggtg gtgtcgcgct
      781 gttgacgaca aaaggtaaag caaccgttgc ttttgcccgt gaagcgagaa ccgaagtccg
      841 taaggtcatt tggccgactc gccaggaaac gctgcacacc acgctgatcg tcgctgcggt
      901 taccgcagtt atgtcactga tcctgtgggg actggatggt attctggttc gcctggtatc
      961 ctttatcact ggcctgaggt tctgagatgt ctgaagcacc taaaaagcgc tggtacgtcg
     1021 ttcaggcgtt ttccggtttt gaaggccgcg tagccacatc gctgcgcgag catatcaaat
     1081 tacacaatat ggaagagctg tttggcgaag tcatggtgcc gactgaagaa gtcgttgaga
     1141 tccgtggcgg ccagcgtcgc aaaagcgaac gcaaattctt cccgggttac gttctggtcc
     1201 agatggtcat gaacgacgca agctggcacc tggtgcgcag cgtgccgcgt gtgatgggct
     1261 ttatcggcgg tacctctgac cgtccggcgc cgatcagcga caaagaagtc gatgcgatca
     1321 tgaaccgcct gcagcaggtt ggcgataagc cgcggccgaa aacgttgttt gaaccgggtg
     1381 aaatggttcg tgttaacgac ggtccgttcg cagactttaa cggcgttgtc gaagaagtcg
     1441 attatgagaa gtctcgcctg aaagtgtctg tttctatctt cggtcgtgcg accccggtag
     1501 agctggactt cagccaggtt gagaaagcgt aaggctgcga tcaaaaaagc agcgatctaa
     1561 tcgttgcata gggcgcaaaa ttgacataca atttcgcgcc ttttgttttt atgggcctta
     1621 tgcccataaa gcgatattta tcacggggag cttctttgaa gcgatactac ccaattcgag
     1681 gaatttagaa tggctaagaa agtacaagcc tatgtcaagc tgcaggttgc agctggtatg
     1741 gcgaacccga gtccgccggt tggtccagca ctgggtcagc agggtgtgaa catcatggaa
     1801 ttctgcaaag cgttcaacgc aaaaacggat tccatcgaaa aaggtctgcc gattccggtt
     1861 gttattaccg tttacgctga ccgttctttc accttcgtta ccaaaacgcc tccggcagct
     1921 gttctgctga aaaaagcggc tggtatcaag tctggttccg gcaagccgaa caaagacaaa
     1981 gtaggtaaaa tttcccgcgc tcagctgcag gaaatcgcgc agaccaaagc tgccgacatg
     2041 accggtgccg acattgaagc gatgactcgc tccatcgaag gtactgcacg ttccatgggc
     2101 ctggtagtgg aggactaaga aatggctaaa ctgaccaagc gtatgcgcgt gatccgtgaa
     2161 aaagttgatg cgaccaaaca gtacgacatc aacgaagcta ttgccctgtt gaaagagctg
     2221 gccactgcta aattcaacga aagcgttgac gttgccgtta acctcggcat cgacgctcgt
     2281 aaatctgacc agaacgttcg tggcgcgact gtactgccgc acggtactgg ccgttctgtt
     2341 cgcgttgccg tatttaccca gggcccgaac gctgaagcag ctaaagctgc tggcgctgag
     2401 ctggtaggta tggaagatct ggctgaccag atcaagaaag gcgaaatgaa cttcgacgtt
     2461 gttatcgcat ccccggatgc aatgcgcgtt gttggccagc tgggccaggt tctgggtccg
     2521 cgcggcctga tgccaaaccc gaaagtcggt accgtaacgc cgaacgttgc tgaagcggtt
     2581 aagaacgcta aagcaggtca ggttcgttac cgtaacgaca aaaacggcat catccacacc
     2641 accatcggta aagtggactt tgacgctgac aaactgaaag aaaacctgga agctctgctg
     2701 gttgcgctga aaaaagcaaa accgagccag gcgaaaggcg tgtacatcaa gaaagttagc
     2761 atctccacca ccatgggtgc tggcgttgcc gttgatcagg ctggtctgag cgcatctgcg
     2821 aactaagatt agtctttacg tgggcggtga ttttgtctac aatcttaccc ccacgtattc
     2881 tgctagttgc agacgtatat ccgaggtatt cgggttgtga caaggcggca acttagtgag
     2941 tcgccaggag catagttaac tatgtgactg gtgcgaacga aggaagccaa cgccgtcaca
     3001 agctgaatag cgacggatag aaaagatttg ttcgttggag cctggcctat ccaggcctcc
     3061 gtcgaagacc gcaggcgtct cgcaagaggc ttaatcccct gcgtagacgg tgacagaacg
     3121 ctaagattat ttttgatact ctggcttgtt tctgctcacc gtattaagac gctcttctcg
     3181 ttgagatgag tgaagtgagt tccggaacat gagttccggc aaacatccag gagcaaagct
     3241 aatggcttta aatcttcaag acaaacaagc gattgttgct gaagtcagcg aagtagccaa
     3301 aggcgcgctg tctgcagtag ttgcggattc ccgtggcgta actgtagata aaatgactga
     3361 actgcgtaaa gcaggtcgtg aagctggcgt atacatgcgt gttgttcgta acaccctgct
     3421 gcgccgcgtc gttgaaggta ctcagttcga gtgcctgaaa gacacgtttg ttggtccgac
     3481 cctgattgca tactctatgg aacacccggg cgctgctgct cgtctgttca aagagttcgc
     3541 gaaagcgaat gcaaaatttg aggtcaaagc tgcagccttt gaaggtgagc tgatcccggc
     3601 gtctcagatc gaccgcctgg caactctgcc gacctacgaa gaagcaattg cacgcctgat
     3661 ggcaaccatg aaagaagctt cggctggcaa actggttcgc acactggctg ctgtacgcga
     3721 tgcaaaagaa gctgcgtaat cgcagttgtc tttatcaagc atttgcttac gtataaactt
     3781 attctgatat tcaggaacaa tttaaatgtc tatcactaaa gatcaaatca ttgaagcagt
     3841 atccgctatg tccgtaatgg acgttgtaga actgatttct gcaatggaag aaaaattcgg
     3901 tgtttccgct gctgctgctg tagctgtagc tgctggcccg gctgaagctg ctgaagaaaa
     3961 aactgaattc gacgtaattc tgaaagctgc tggcgctaac aaagttgctg ttatcaaagc
     4021 agtacgtggc gcaactggcc tgggtctgaa agaagctaaa gacctggtag aatctgctcc
     4081 ggccgctctg aaagaaggcg tgagcaaaga tgacgctgaa gcactgaaaa aatctctgga
     4141 agaagctggc gctgaagttg aagttaaata agccaaccct tccggttgca gcctgagaaa
     4201 tcaggctgat ggctggtgac tttttagtca ccagcctttt tgcgctgtaa ggcgccagta
     4261 gcgtttcaca ctgtttgact actgctgtgc ctttcaatgc ttgtttctat cgacgactta
     4321 atatactgcg acagagcgta cgttctgtgt aaatcgcaat gaaatggttt aagcgtgata
     4381 gcaacaggca ttgcggaaag tatccatttt ccggtcaaca aaatagtgtt gcacaaactg
     4441 tcccccgcag gacagatggg tcgacttgtc agcgagctga ggaaccctat ggtttactcc
     4501 tataccgaga aaaaacgtat tcgtaaggat tttggtaaac gtccacaagt tctggatgta
     4561 ccttatctcc tttctatcca gcttgactcg tttcagaagt ttatcgagca agatcctgaa
     4621 gggcagtacg gcctggaagc agccttccgt tccgtgttcc cgattcagag ctacagcggt
     4681 aattccgagc tgcagtacgt cagctaccgc cttggcgaac cggtgtttga cgttcaggaa
     4741 tgtcagatcc gtggcgtgac ctattccgca ccgctgcgcg taaaactgcg tctggtgatc
     4801 tacgagcgcg aagcgccgga aggcaccgtt aaagacatta aagaacaaga agtctacatg
     4861 ggcgaaattc cgctcatgac cgacaacggt acctttgtta tcaacggtac tgagcgtgtt
     4921 atcgtttctc agctgcaccg tagtccgggc gtcttctttg actccgacaa aggtaaaact
     4981 cactcttcgg gtaaagtgct gtataacgcg cgcatcattc cttaccgtgg ttcctggctg
     5041 gacttcgaat tcgatccgaa ggacaacctg ttcgtgcgta tcgaccgtcg ccgtaaactg
     5101 cctgcgacca tcatcctgcg tgcgctgaac tacaccactg agcagatcct tgacctgttc
     5161 tttgagaaag tcgtcttcga aattcgcgac aacaagctgc agatggagct gattccagaa
     5221 cgtctgcgcg gcgaaaccgc gtcgttcgat atcgaagcta acggcaaggt gtacgttgaa
     5281 aaaggccgtc gcattaccgc gcgtcatatc cgtcagctgg aaaaagacga tatcaagcat
     5341 atcgaagttc cggttgagta catcgcaggt aaagtcgtct ctaaagacta cgttgacgaa
     5401 tctactggcg agctgatctg cgcggcgaac atggagctga gcctggatct gctggctaag
     5461 ctgagccagt ccggccacaa gcgtatcgaa acgctgttta ccaacgatct ggaccacggc
     5521 ccgtacattt ctgaaacggt acgcgtcgat ccaactaacg atcgtctgag cgcgctggta
     5581 gaaatctacc gcatgatgcg ccctggtgag ccgccgacac gcgaagcggc tgaaagcctg
     5641 tttgagaacc tgttcttctc cgaagaccgc tatgacctgt ctgcggtggg tcgtatgaag
     5701 ttcaaccgtt ctctgctgcg cgacgaaatc gaaggttccg gtatcctgag caaagacgac
     5761 atcattgatg tcatgaagaa gctcatcgat atccgtaacg gtaaaggcga agtggatgat
     5821 atcgaccacc tcggcaaccg tcgtatccgt tccgtcggcg aaatggcgga aaaccagttc
     5881 cgcgttggcc tggtgcgtgt agagcgtgcg gtgaaagagc gtctgtctct gggcgatctg
     5941 gataccctga tgcctcagga tatgatcaac gccaagccga tttccgccgc agtgaaagag
     6001 ttctttggtt ccagccagct gtctcagttt atggaccaga acaacccgct gtctgagatt
     6061 acgcacaaac gtcgtatctc cgcactcggc ccaggcggtc tgacccgcga acgcgcaggc
     6121 ttcgaagttc gagacgtaca cccgacgcac tacggtcgcg tatgtcctat cgaaacgccg
     6181 gaaggtccga acatcggtct gatcaactcc ctgtccgtgt acgcacagac taacgaatat
     6241 ggcttccttg agacgccgta ccgtcgtgtg gttgatggcg tggttactga cgaaattcat
     6301 tacctgtctg ctatcgaaga aggcaactac gttatcgctc aggcgaactc caacctggat
     6361 gacgaaggcc actttgtaga agatctggta acctgccgta gcaaaggcga atccagcttg
     6421 ttcagccgcg accaggttga ctacatggac gtttccaccc agcaggtggt ctccgtcggt
     6481 gcgtccctga tcccgttcct ggaacacgat gacgccaacc gtgcattgat gggtgcgaac
     6541 atgcaacgtc aggcggttcc gactctgcgt gctgataagc cgctggtggg taccggtatg
     6601 gaacgtgctg tcgccgtcga ctccggtgtt actgcagtag ctaaacgtgg cggtactgtt
     6661 cagtacgtgg atgcatcccg tatcgttatc aaagttaacg aagacgagat gtacccgggt
     6721 gaagcaggta tcgacatcta taacctgacc aaatacaccc gctctaacca gaacacctgt
     6781 atcaaccaga tgccatgtgt gtctctgggc gagccggttg aacgcggcga cgtgctggca
     6841 gacggtccgt ccaccgacct cggtgaactg gcgctcggtc agaacatgcg cgtggcgttc
     6901 atgccgtgga acggctacaa cttcgaagac tccatcctcg tttccgagcg tgttgtccag
     6961 gaagaccgtt tcaccaccat ccacattcag gaactggcgt gcgtgtcccg tgacaccaag
     7021 ctggggccgg aagagatcac cgctgacatc ccgaacgtgg gtgaagctgc gctctccaaa
     7081 ctggatgaat ccggtatcgt ttacatcggc gcggaagtga ctggcggcga cattctggtc
     7141 ggtaaggtaa cgccgaaagg tgaaacccag ctgacgccgg aagagaaact gctgcgtgcg
     7201 atcttcggtg agaaagcgtc tgacgttaaa gactcttctc tgcgcgtacc taacggtgtc
     7261 tccggtacgg ttatcgacgt tcaggtcttt actcgcgatg gcgtagaaaa agacaaacgt
     7321 gctctggaaa tcgaagagat gcagctcaag caggcgaaaa aagacctgtc tgaagaactg
     7381 cagatcctcg aagcgggcct gtttagccgt atccgtgcgg tgttggtgtc cggcggcgtt
     7441 gaagctgaga agctcgacaa actgccgcgc gaccgctggc tggaactcgg tctgaccgac
     7501 gaagagaaac aaaatcagct ggaacaactg gctgagcagt atgacgaact gaaacacgag
     7561 ttcgagaaaa aacttgaagc gaagcgccgt aaaatcaccc agggcgacga tctggcgccg
     7621 ggcgtgctga agatcgtgaa ggtctatctg gccgttaaac gccgtatcca gccgggtgat
     7681 aagatggcag gtcgtcacgg taacaagggt gttatctcta agatcaaccc gatcgaagac
     7741 atgccttacg atgaaaacgg cacgccggta gacatcgtac tgaacccgct gggcgtaccg
     7801 tctcgtatga acatcggtca gattctggaa acccacctgg gtatggctgc gaaaggtatt
     7861 ggcgacaaga ttaacgccat gctgaaacag cagcaggaag tcgcgaaact gcgcgaattc
     7921 atccagcgtg cctacgatct gggcgccgac gttcgtcaga aagtcgacct gagcaccttc
     7981 agcgatgatg aagtgctgcg tctggcagaa aacctgcgca aaggtatgcc gattgccaca
     8041 ccagtgttcg acggtgcgaa agaagcggaa atcaaagagc tgctgaaact gggcgacctg
     8101 ccgacctccg gtcagatcac cttgttcgat ggccgtacgg gtgaacagtt cgaacgtccg
     8161 gtaaccgtcg gttacatgta catgctgaaa ctgaaccacc tggttgatga caagatgcat
     8221 gcgcgttcta ccggttctta cagcctggtt actcagcagc cgctgggtgg taaggcgcag
     8281 ttcggtggtc agcgcttcgg ggagatggaa gtgtgggcgc tggaagctta cggcgccgcc
     8341 tacaccctgc aggaaatgct caccgttaag tctgatgacg tgaacggtcg taccaagatg
     8401 tataagaaca tcgtggacgg caaccatcag atggaaccgg gtatgccgga atccttcaac
     8461 gttctgttga aagagatccg ctcgctgggc atcaacatcg aactggaaga cgagtaattc
     8521 tcgctcaaac aggtcactgg tgtcggggta aaacccgaca ccagattgtg ctaactccga
     8581 cgggagcaaa tccgtgaaag atttattaaa gtttctgaaa gcgcagacta aaaccgaaga
     8641 gtttgatgcg atcaaaattg ctctggcttc gccagacatg atccgttcat ggtctttcgg
     8701 tgaagttaaa aagccggaaa ccatcaacta ccgtacgttc aaacctgagc gtgacggcct
     8761 tttctgcgcc cgtatctttg ggccggtaaa agactacgag tgcctgtgcg gtaagtacaa
     8821 gcgcctgaaa caccgtggtg ttatttgtga gaagtgcggc gttgaagtga cccagaccaa
     8881 agtacgccgt gagcgtatgg gccacatcga gctggcgtct ccgactgctc acatctggtt
     8941 cctgaaatcg ctgccgtccc gtatcggtct gctgctcgat atgccgttgc gtgatatcga
     9001 acgcgtactg tacttcgaat cttatgtggt tatcgaaggc ggtatgacca acctggaacg
     9061 tcaacagatc ctgactgaag agcagtatct ggacgcgctg gaagagttcg gtgacgaatt
     9121 cgacgcgaag atgggtgcgg aagctatcca ggccctgctg aagagcatgg atctggagca
     9181 agagtgtgaa actctgcgcg aagagctgaa cgaaaccaac tccgaaacta agcgtaaaaa
     9241 gctgaccaag cgtatcaaac tgctggaagc cttcgtacag tctggcaaca agccagagtg
     9301 gatgatcctg accgttctgc cggttctgcc gccagatctg cgtccgctgg ttccgctgga
     9361 tggtggtcgt ttcgccacgt cagatctgaa cgatctgtat cgtcgcgtga tcaaccgtaa
     9421 caaccgtctg aaacgtctgc tggatctggc tgcgccggac atcatcgtac gcaacgaaaa
     9481 acgtatgctg caggaagcgg tcgacgccct gctggataac ggtcgtcgcg gtcgtgcgat
     9541 caccggttct aacaaacgtc ctctgaaatc tttggccgac atgatcaaag gtaagcaggg
     9601 tcgtttccgt cagaacctgc tcggtaagcg tgttgactac tccggtcgtt ctgtaatcac
     9661 cgtaggtcca tacctgcgtc tgcatcagtg cggtctgccg aagaaaatgg cgctggagct
     9721 gttcaaaccg ttcatctacg gcaaactgga actgcgagga ctcgccacca ctatcaaagc
     9781 cgcgaagaaa atggttgagc gcgaagaagc tgtcgtttgg gatatcctgg acgaagtgat
     9841 ccgcgaacac ccggtactgc tgaaccgtgc accaacactg caccgtttgg gtatccaggc
     9901 atttgaaccg gtactgatcg aaggtaaagc tatccagctg cacccgctgg tttgtgcggc
     9961 atataacgcc gacttcgatg gtgaccagat ggctgttcac gtaccgctga cgctggaagc
    10021 ccagctcgaa gcgcgtgcgc tgatgatgtc taccaacaac atcctgtctc cggcgaacgg
    10081 cgaacctatc atcgttccgt ctcaggacgt ggtattgggt ctgtactaca tgacccgtga
    10141 ctgtgttaac gccaaaggcg aaggcatggt gctgactggc ccgaaagaag ctgagcgtat
    10201 ctatcgcgca ggtctggcct ctctgcatgc gcgcgttaaa gtgcgtatca ctgaatatga
    10261 aaaagatgaa aacggcgaat tcgttgcgca caccagcctg aaagacacga ccgttggtcg
    10321 cgccattctg tggatgatcg taccgaaagg tctgcctttc tccatcgtca accaggcgct
    10381 gggcaagaaa gcgatctcca aaatgctgaa cacttgctac cgtattctgg gcctgaaacc
    10441 gaccgttatt tttgcggacc agacgatgta caccggcttt gcttatgcag cgcgttcagg
    10501 tgcgtccgtt ggtattgatg acatggtcat cccggagaaa aaacacgaga tcatctctga
    10561 agcggaagcc gaagttgctg agatccagga gcagttccag tctggtctgg taaccgctgg
    10621 cgaacgctat aacaaagtta tcgatatctg ggctgcggcg aacgatcgtg tatccaaagc
    10681 gatgatggat aacctgcaaa ccgaaaccgt gattaaccgt gacggccagg aagagcagca
    10741 ggtttccttc aacagcatct acatgatggc cgactccggt gcgcgtggtt ctgcggcaca
    10801 gattcgtcag ctggcaggta tgcgtggtct gatggcgaag ccagatggct ccatcatcga
    10861 aacgccaatc accgcgaact tccgtgaagg tctgaacgta ctccagtact tcatctccac
    10921 gcacggtgcg cgtaaaggtc tggcggatac cgcactgaaa accgcgaact ccggttatct
    10981 gacccgtcgt ctggttgacg tcgcgcagga tctggtggtg accgaagatg actgtggtac
    11041 gcacgaaggt atcctgatga ccccggttat cgagggtggc gacgtgaaag agccgctgcg
    11101 tgaccgcgtt ctgggtcgtg tgacggcgga agatgtgctg aagccgggta cggcggacat
    11161 tctggttcca cgcaacacgc tgctgcacga acagtggtgt gacctgctgg aagcaaactc
    11221 cgttgacgcc gttaaagtgc gttccgttgt atcctgcgat accgattttg gtgtatgtgc
    11281 gcactgctat ggtcgtgacc tggcgcgtgg ccacatcatc aacaaaggtg aagctatcgg
    11341 cgttatcgcg gcacagtcca tcggtgaacc gggtacacag ctgacgatgc gtacgttcca
    11401 catcggtggt gcggcatcgc gtgcggctgc tgaatccagc atccaggtta agaacaaagg
    11461 tagcatcaag ctcagcaacg tgaagtcggt tgtgaactcc agcggtaaac tggttatcac
    11521 ttcccgtaac accgaactga agctgatcga cgaattcggt cgtaccaaag agagctataa
    11581 agtgccttat ggcgcagtca tggcgaaagg tgatggcgag caggttgccg gcggcgaaac
    11641 cgtggcaaac tgggacccgc acaccatgcc ggttatcacc gaagtgagtg gtttcatccg
    11701 cttcactgac atgatcgacg gtcagaccat tacgcgtcag accgacgaac tgaccggttt
    11761 gtcttcgctg gtggttctgg attcggctga acgtactacc ggtggtaaag atctgcgtcc
    11821 ggcgctgaaa atcgttgatg ctcagggtaa tgacgttctg atcccgggta ccgatatgcc
    11881 tgcgcagtac ttcctgccgg gtaaagcgat tgtacagctg gaagatggcg tacagatcag
    11941 ttctggtgac accctggcgc gtattccgca ggaatccggc ggtaccaagg atatcaccgg
    12001 tggtctgccg cgcgttgccg atctgttcga agcgcgtcgt ccgaaagagc cggccattct
    12061 ggcggaaatc gcaggtatcg tttccttcgg taaagaaacc aaaggcaaac gtcgcctagt
    12121 gattacgccg gttgatggta gtgacccgta cgaagagatg attccgaaat ggcgtcagct
    12181 caacgtgttc gaaggggaac gtgtagaacg tggtgatgtg atttccgatg gtccggaagc
    12241 gccgcacgac attctgcgtc tgcgtggcgt tcatgctgtg acgcgttata ttgttaacga
    12301 agttcaggat gtataccgtc tgcagggcgt taagattaac gataaacaca tcgaagttat
    12361 cgttcgtcag atgctgcgta aagcgaccat cgaaagcgcc ggtagttccg acttcctgga
    12421 aggcgaacag gttgaatact ctcgcgtcaa gatcgctaac cgcgagctgg aagcgaacgg
    12481 caaagtgggg gctaccttct cccgcgatct gctgggtatt accaaagcgt ctctggcaac
    12541 cgagtcgttc atctctgccg catcgttcca ggagaccacg cgtgtcctga ccgaagcagc
    12601 cgttgcgggt aaacgcgacg aactgcgcgg cctgaaagag aacgttatcg tgggtcgtct
    12661 gattccggcc ggtaccggtt atgcgtacca ccaggatcgt atgcgccgtc gcgccgcggg
    12721 cgagcagcca gcaacaccgc aggtcactgc ggaagatgca tctgcaagcc tggcagagct
    12781 gctgaacgca ggtctgggcg gttctgataa cgagtaatcg ttaaatggtg gaggggtatt
    12841 tatccctcca ccagcttcat gctggatacc gaattccggg tcgcttgcct acaaggaaag
    12901 aaaatgccag cgattatttc attaatctat ttaatgttta gtcttttagt atttacaaaa
    12961 aagataacca tttcaaacgt tctgtccgct tttttattgt ttctatcgtt atatatactt
    13021 ca
//
LOCUS       DAJVKX010000125        12989 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.125, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000125 DAJVKX010000000
VERSION     DAJVKX010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12989
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.125"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            187..1554
                     /locus_tag="OPY25_003579"
     CDS             187..1554
                     /locus_tag="OPY25_003579"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HCS0929088.1"
                     /translation="MESCLDIFKIVIGPSSSRTVGPMRAACHFISLLREQETLPLIRE
                     IEIELYGALSLSRKCHNVDTALYLGLLGCQPENVDLRSHMAVIKRAENENKIELPLSD
                     AGGITIKVKIIANHQAHPGHPYAMTFCARDDYFTVYEETWFSTGAGQVRKHGEPLTPS
                     LPLRTVSPFEFSHAAQLLALCRRNGLSVAALMMKNELCRHSPQTLQNYLAQIWDVMQQ
                     AVYRGLHTEGVLPGPYQVPRRACALHKTLQANRSASDFLTALNWVNAFAIAVSEENAS
                     GGQIVTAPTNGACGIIPAALCWYDKFVTPLEPGALTRFFLTAAAIAMLFKQNASILGS
                     EVGCQGEIGVACSMAAAGLAELMGASVEQTLSAAEIAMEHHLGLTCDPLGGQVQIPCI
                     ERNAISAVKAINAATMAMSRVSEPCISLDEIIAAMYETGKDMSAKYRETYHGSLGKIQ
                     PRKRG"
     gene            1559..1948
                     /locus_tag="OPY25_003580"
     CDS             1559..1948
                     /locus_tag="OPY25_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929089.1"
                     /translation="MKYNTMNNDEIILSLCARLKETRLSLAMTQQQLADRAHVGIATI
                     KRIEKGGGLNLDTLISLLRALDKLHNLDAVLFESELRNFHESYEGGEGSGRLQVRQQA
                     ADLNNKSSAPQSEEVNYSAALENSLCW"
     gene            complement(1937..2794)
                     /gene="fghA"
                     /locus_tag="OPY25_003581"
     CDS             complement(1937..2794)
                     /gene="fghA"
                     /locus_tag="OPY25_003581"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HCS0929090.1"
                     /translation="MEMLEEHRCFGGWQQRWRHHAATLNCAMTFSIFLPPTQDNEPPP
                     VLYWLSGLTCNDENFTTKAGAQRIAAELGIVLVMPDTSPRGEQVADDSGYDLGHGAGF
                     YLNATQPPWASHYRMYDYLRDELPALIQTQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSISAFAPIVNPSRVPWGIKALTAYLGEDESAWTEWDSCELMLASQPQDAIPVLID
                     QGDSDQFLADQLQPAVLAEAARQTAWPMTLRIQPGYDHSYYFIASFIEDHLRFHARYL
                     RDEHETSPT"
     gene            3121..3789
                     /gene="folE"
                     /locus_tag="OPY25_003582"
     CDS             3121..3789
                     /gene="folE"
                     /locus_tag="OPY25_003582"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HCS0929091.1"
                     /translation="MPSLSKEAALVHDALVARGLETPLRPPMDELDNETRKSLIAGHM
                     TEIMQLLNLDLSDDSLMETPHRIAKMYVDEIFAGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     TALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAV
                     RHHP"
     gene            3804..4946
                     /locus_tag="OPY25_003583"
     CDS             3804..4946
                     /locus_tag="OPY25_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HCS0929092.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAIVP
                     EDAWSWAILDIVAQAKFLTLFALLFGAGLQMLLPRGKQWIQSRLTLLVLLGFIHALFF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGILLYLVGIGVLLLLGVVSSSETSRA
                     WTPDASAILYEKYWKLNGGMEAISNRAEMLSNSLLALGAQYGWQLAGMILLGAALMRS
                     GWLKGQYSLRHYRRTGVLLVALGLMINLPAVILQWRLDWAYRWCAFLLQAPRELSAPL
                     QTLGYAALMFGFWPQLSRCRLTLAIACVGRMALTNYLLQTIICTTLFYQFGLFMKFNR
                     LELLFFVVPVWAINLLFSVIWLRFWRQGPVEWLWRQLTLRASGSLR"
     gene            5096..6118
                     /gene="galS"
                     /locus_tag="OPY25_003584"
     CDS             5096..6118
                     /gene="galS"
                     /locus_tag="OPY25_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HCS0929093.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSALVSPDTRDAVMQAVTLLG
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALTDRELSDFMDQIPGMVLINRIVPGYAHRCVCLDN
                     VSGARMATRMLLNNGHQRIGYLAFSHRIEDDAMRREGWLHALQEQGVAASESWIGTGT
                     PDMQGGESAMVELLGRNLQLTAVFAYNDNMASGALTALKDNGIAIPLHLSVIGFDDIP
                     IARYTDPQLTTVRYPIASMAKIATELALQGAAGTLDITATHCFMPTLVRRHSVAWRQN
                     AVLITN"
     gene            6617..7615
                     /gene="mglB"
                     /locus_tag="OPY25_003585"
     CDS             6617..7615
                     /gene="mglB"
                     /locus_tag="OPY25_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HCS0929094.1"
                     /translation="MNKRVLTLSAVMASLLFGAHAHAADTRIGVTIYKYDDNFMSVVR
                     KVIEKDGKSAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGVIQGDLIAKHWQANQGWDLNK
                     DGKIQYVLLKGEPGHPDAEARTTYVVKELNDKGIQTEQLALDTAVWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGAMAGT
                     VLNDANNQAKATFDLAKNLAEGKGAADGTSWKIENKIVRVPYVGVDKDNLSEFTQK"
     gene            7749..9267
                     /gene="mglA"
                     /locus_tag="OPY25_003586"
                     /pseudo
     CDS             7749..9267
                     /gene="mglA"
                     /locus_tag="OPY25_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
     gene            9283..10293
                     /gene="mglC"
                     /locus_tag="OPY25_003587"
     CDS             9283..10293
                     /gene="mglC"
                     /locus_tag="OPY25_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HCS0929095.1"
                     /translation="MSALNKKSFLTWLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMENANKVFPEMAT
                     MPIALVILIVCAIGAVIGLVNGIIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVAMGSFRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVALNLLMIYALSGVFYAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVFGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGGIIIFAVALDSLKYAR
                     KK"
     gene            complement(10368..11602)
                     /gene="preA"
                     /locus_tag="OPY25_003588"
                     /pseudo
     CDS             complement(10368..11602)
                     /gene="preA"
                     /locus_tag="OPY25_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461132.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
     gene            complement(11596..12837)
                     /locus_tag="OPY25_003589"
     CDS             complement(11596..12837)
                     /locus_tag="OPY25_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCS0929096.1"
                     /translation="MPQQNYLDELTPGFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQRGCTRSGIDKPIDIARLQ
                     RFITDFEQQTAMQIYQPGSKTRGKVAIIGAGPAGLQASVTLTHLGYDVTIYEKQPQPG
                     GWLRHGIPAFRLPQSVLDQEIARIVEMGVNIKCNCDVGGSLSLAQLKAEYRAVLMTVG
                     MSCGSDLPLFEQASHVEIAVDFLQRARQADGDISVPRSALIIGGGDVAMDVASTLKIL
                     GCPSVTCVAREELAEFPASEKEFTSTQALGVSIIDGFTPVAVSGNKVTFHHVRHSGEL
                     TLEAENIILAVGQHARLDNFAEIKAQHNIIDTHNYQTDDPAIFAAGDIVKGDKTVVYA
                     VKTGKEAAQAIHHYLEEACSC"
BASE COUNT         3095 a         3183 c         3499 g         3212 t
ORIGIN      
        1 aatggctctt ttgcggcgtg gaatctcgtg ctatcacaga tatcacagcc agaaaagggc
       61 taaaaaagcg ttgtttttga taccaggtaa agttcagaca caaaaggtat cacttttgat
      121 atgccaactg tgcgaggatg ttatttatta ctgaacgcga atgagactga aaggattgat
      181 ataacgatgg agagttgcct tgatatattc aaaatagtaa taggtccatc cagctcacgt
      241 accgtagggc cgatgcgcgc cgcctgtcac tttatttcat tgctcagaga acaagagacg
      301 ttgccgctaa ttcgggaaat tgaaatcgag ctgtatggcg cgttatcgtt aagccgcaag
      361 tgccacaatg tggataccgc cctgtatctt gggctgctgg gttgccagcc ggagaatgtc
      421 gatctccgtt cgcatatggc ggtgattaag cgtgcggaaa atgaaaacaa aatcgaactc
      481 ccgctctctg acgcgggcgg aatcacgata aaagtcaaga ttatcgccaa tcaccaggcg
      541 catccaggcc atccttatgc catgacgttt tgcgccaggg atgattattt tacggtgtat
      601 gaagagacct ggttttctac cggcgccggg caggttcgta aacatggcga gccgctgacg
      661 ccatcgcttc ctttgcgtac agtgtcgccc tttgaattta gtcatgccgc gcagttgctg
      721 gcgctgtgtc ggcgtaacgg cctgtccgtg gcggcgctga tgatgaaaaa tgagctgtgc
      781 cgccactcgc cacagacgtt gcagaattat ctggcgcaaa tatgggacgt gatgcagcag
      841 gcggtttatc gcggcctgca tactgagggg gtattacccg gtccctatca ggtaccgcgg
      901 cgcgcctgtg cgttacataa gacgttacag gctaaccgct ccgccagcga ttttttaacc
      961 gcgctgaact gggtcaatgc cttcgcgatt gcggtaagcg aagaaaatgc cagcggcgga
     1021 cagattgtta ccgcgccaac caatggcgcg tgcggcatca ttccggcagc gctctgctgg
     1081 tatgataaat ttgtcacgcc gctggagccc ggtgctctga cccgtttctt cctgaccgcc
     1141 gccgctatcg cgatgctgtt taaacaaaac gcctctattc tgggatctga agttggctgt
     1201 cagggggaaa tcggcgtggc gtgctcaatg gcggcggcgg gcctggctga actgatgggt
     1261 gcatccgtgg agcaaacgct gagcgccgct gaaattgcca tggaacatca tctgggattg
     1321 acctgcgatc cgctgggcgg gcaggtacaa attccctgca tagagagaaa tgccatctct
     1381 gccgtgaaag cgataaacgc ggcgacgatg gcgatgagtc gcgtaagcga accctgtatt
     1441 tcgctcgatg agatcattgc tgcgatgtac gagaccggta aagacatgag cgctaaatac
     1501 cgtgaaacgt atcatggttc gctggggaaa attcagccgc gcaagagagg gtaacagcgt
     1561 gaaatacaat acgatgaata acgatgagat tatcctgtcg ttgtgcgccc gcttaaagga
     1621 gacgcgtctg tctcttgcga tgacccagca gcagcttgcc gatcgcgcgc acgttggcat
     1681 tgccaccatc aagcgtatcg agaagggggg agggctcaat cttgatacgc taatttctct
     1741 cctgcgggcg ctggataagt tgcataatct tgatgcggtg ctgtttgaat ccgaactgcg
     1801 taattttcac gaaagttatg aaggcggaga gggcagcggc cgccttcagg tacgccagca
     1861 ggccgcggat ttaaataata aatcttccgc gccgcagtcg gaggaggtga actacagcgc
     1921 ggcgctggaa aattcattat gttggtgacg tctcatgctc gtcccgtaaa taccgggcat
     1981 gaaagcgcag atggtcctca atgaaggacg caataaaata atagctatga tcgtaaccgg
     2041 gctggattcg tagcgtcatc ggccaggcgg tttgccgcgc ggcttccgcc agtacggcgg
     2101 gctgaagctg atcggcgagg aattgatcgc tgtcaccctg atcgatgagc acaggaatgg
     2161 cgtcctgcgg ctggctggcc agcattaatt cgcagctatc ccactcagtc caggctgatt
     2221 catcttcgcc gagataagcg gtaagcgctt tgattcccca cggcacgcgg ctggggttga
     2281 cgatgggcgc aaaagcagag atgctggtgt atttgcccgg atttttcagc gccatgatta
     2341 acgcgccgtg gccgcccatc gagtgcccgc tgatggcgca acggtcgctg acgttaaact
     2401 gtgtctggat aagcgccgga agctcatcgc gcaggtaatc gtacatgcga taatggctgg
     2461 cccagggcgg ctgtgtggca ttgagataaa acccggcgcc gtggcctaaa tcgtatccgc
     2521 tatcgtcggc gacctgttca ccgcgtggac tggtatccgg catcaccaat acaatgccca
     2581 gttctgctgc gatacgctgc gcgcctgctt tggtggtaaa attctcatca ttgcaggtca
     2641 acccggacaa ccagtacagt accggaggcg gttcattatc ctgagtcggc ggaagaaaaa
     2701 tgctgaatgt catggcgcag tttagcgtgg cggcatgatg acgccagcgc tgctgccagc
     2761 cgccaaaaca tcggtgctct tcgagcattt ccatgcgggg gctcctttta tagtgaacct
     2821 gataaggtat gcagattctt cataatacag attattcacc gcgttgtgag taactttcac
     2881 ttccgtaata cataaacatg cttcatcatt taaataacgt tgcgttaaca aatatgccct
     2941 ttgtcctgcc agcattctcg caccggaaaa gatgtcatga aaggcagcga caatttcaac
     3001 aattatgggc gtgaatactg gattatgtgc gctacctcac gcacaataat cacactgtca
     3061 caatattgac aaactttgcc ccaagggcag aggcgccaca cctgcaggag aacacgatta
     3121 atgccatcac tcagtaaaga agcggccctg gttcatgacg cgctggttgc ccgggggctg
     3181 gaaacgccgc tgcgcccgcc tatggatgaa ctggataatg aaacgcgaaa aagccttatc
     3241 gcagggcata tgactgagat tatgcagttg ctgaatctcg atttgagcga tgacagtctg
     3301 atggaaacgc cgcatcgtat cgctaagatg tacgttgacg agatttttgc tggcctcgac
     3361 tatgctaatt tcccgaaaat taccctcatt gaaaataaaa tgaaggtgga tgaaatggtc
     3421 accgtccgcg atatcacgct gaccagcacc tgtgaacatc acttcgtgac cattgatggc
     3481 aaagcgaccg tcgcgtatat ccccaaagat tccgtgatcg gcctgtcgaa aattaaccgc
     3541 atcgtgcaat tcttcgccca gcgtccgcag gttcaggaac gtttgaccca acaaattctg
     3601 acggcgctgc aaaccttgct cggcaccaat aatgtagcgg tatcgattga tgcggtgcat
     3661 tactgcgtga aagcgcgcgg tattcgtgac gcaaccagcg ccacgacgac gacgtcgctg
     3721 ggcggattgt ttaagtccag ccagaatacg cgccaggagt ttctgcgtgc cgttcgccat
     3781 catccatgat taaggcggag acgatggagc gtaatgtcac gctggatttt gtacgtggcg
     3841 tcgctatcct cggtatcctg cttcttaaca ttagcgcctt tggattgccg aaggcggctt
     3901 atctcaatcc cgcctggtac ggcgcgatcg ttcccgaaga cgcctggtcc tgggcgattc
     3961 tcgatattgt ggcgcaggct aagtttctta cgctgttcgc gttgttgttt ggcgcggggc
     4021 tacaaatgct gcttccgcgt ggtaaacagt ggattcagtc gcgcttaacg ctattggtac
     4081 tgttaggttt tatccatgcg ttattctttt gggacggcga cattctgctg gcctacggtc
     4141 tggtcggatt aatttgctgg cgactggtac gcgacgcgcc ttcggtaaaa agcctgttca
     4201 ataccggcat actcctttat ctggtcggga ttggcgtact actgctgctg ggtgtggtat
     4261 cgagtagcga aaccagccgc gcctggacgc cggatgcgtc ggcaatattg tatgaaaaat
     4321 actggaagct gaacggcggc atggaggcta tcagcaaccg ggcagagatg ctgtcaaata
     4381 gtttactggc gctcggcgcg cagtatggct ggcaactggc aggtatgata ctgctgggcg
     4441 ccgcgctaat gcgtagcggc tggctgaaag gccagtacag tctgcggcac tatcgccgta
     4501 ccggggttct gctggtggcg ttagggctaa tgatcaacct gcctgcggtc attttacaat
     4561 ggcggctgga ctgggcgtac cgctggtgcg ccttcttatt gcaggcgccg cgcgaactga
     4621 gcgcgccgtt gcaaacgctg ggctatgccg cgctgatgtt tggcttctgg ccgcagctta
     4681 gccgatgcag actgacgctt gccattgcct gcgtagggcg aatggcgctg accaattatt
     4741 tgctgcagac gatcatctgt accacgctgt tttatcagtt tggcttattt atgaaattca
     4801 atcgactgga actcttgttc tttgtcgttc cggtatgggc aataaacctt ctcttttccg
     4861 tcatctggct acgtttctgg cgacagggac cggtcgagtg gttatggcgt caactcacgt
     4921 tgcgcgcgtc aggatcgctc agataacgat ctggatcaca ttcattaaca aaatggctgt
     4981 aaccgtttcc atccctgtga tgtttctcac gcagccctgg gcagggtgct gacaaaatag
     5041 ccgcctgcta acggggcatt tgtgagcatt tttgaactca aacagggcag tgaatatgat
     5101 caccattcgt gatgtagcgc gccaggctgg cgtgtctgta gcgaccgttt cccgcgtact
     5161 gaataacagc gcgttggtca gtcccgacac ccgtgacgcc gttatgcagg ccgtcaccct
     5221 gctgggatat cggccaaatg cgaatgcgca agcgctggcc actcaggtga gcgataccat
     5281 cggcgtcgta gtcatggatg tttccgatgc ctttttcggc gctctggtga aagccgtaga
     5341 tctggtcgcg cagcagcacc agaaatatgt tctcattggc aacagttatc atgaggcgga
     5401 aaaagagcgc catgcgattg aagtcttgat ccgtcagcgt tgtaacgcat tgattgttca
     5461 ctcaaaagcc ttaaccgatc gcgagctgag cgactttatg gatcagatcc ccggtatggt
     5521 gctgattaac cgtatcgtgc cgggttatgc gcatcgttgt gtctgtctcg acaatgtgag
     5581 cggcgccaga atggcgaccc gaatgttgct gaataatgga catcaacgca tcggctacct
     5641 ggccttcagc caccgtattg aagatgacgc gatgcgcaga gaagggtggt tacacgcgct
     5701 gcaagagcag ggggttgctg cgtcggagag ctggattggc accggcacgc cggatatgca
     5761 gggcggcgag tcggcaatgg ttgagttgct gggacgcaat ctgcaactga cggcggtatt
     5821 tgcctataac gataacatgg cgtcgggcgc gctgacggcg ttaaaagata acggcatcgc
     5881 cattcccttg catctgtctg tcatcggttt cgatgatatc cctattgctc gttataccga
     5941 tcctcagttg actaccgtgc gctatcctat tgcttctatg gcgaaaatcg cgaccgagct
     6001 ggcgttacag ggggccgcag gcacgctgga tatcacggcg acgcactgct tcatgccgac
     6061 gctggtacgg cgccattcgg tggcgtggcg acagaatgcg gtactgatca ctaactgatt
     6121 acgccccgca tgtaaccgtt ttcaatctgt gagtaaattc acagtttatt aacattgtga
     6181 tagctatgat gacaacgttt gtcgcactgt aactaatgtg taacagttag ttgttagttt
     6241 tgctggggta tttcgcttat aaaaaccatt atcacaatat cccgcgacta ccggacaaaa
     6301 ataaagagtt gaataagagc ttatcccatt agggctattt tacttgccat tttggacctg
     6361 ggcagtgctc gccaaaacgc gttagcgttt tgaacgccgc tagcagcggc ccgaagggcg
     6421 agcgtagcga gtcaaacctc acgtactacg tgtacgctcc ggtttttgcg cgctgtccgt
     6481 gtccaaactg gctgcgccaa taacgcctgg tgggataggc tctaaatacg cttcggcgtt
     6541 cagtaacatg cgttaacgtg ctgaacagcc gggcattttt ttacgctata ccctacataa
     6601 taaaaccgga gctaccatga ataagagggt actgaccctt tctgccgtga tggcaagtct
     6661 gttattcggc gcgcacgcac acgcggctga tactcgtatt ggcgtgacga tttataaata
     6721 tgacgataac tttatgtccg tggtgcgtaa ggttattgaa aaagatggca aatccgcgcc
     6781 ggatgttcag ctactgatga atgactcgca aaacgatcaa tctaaacaga atgatcaaat
     6841 tgacgtttta ttggcgaaag gggttaaagc tctggcgatt aacctggtcg acccggcagc
     6901 cgccggtacg gtgattgaga aagcgcgcgg gcaaaatgtg ccggtggtgt tctttaacaa
     6961 agagccttcc cgcaaagcgc tggacagcta tgacaaggcg tattatgtcg ggactgactc
     7021 taaagaatcc ggtgtgattc agggcgactt gattgccaaa cactggcagg cgaatcaggg
     7081 ttgggatctg aataaagacg gtaaaattca gtatgttctg ctgaaaggcg agccggggca
     7141 cccggatgct gaagcccgta cgacgtatgt ggtgaaagag ttaaatgata aaggtattca
     7201 gaccgagcaa ctggcgttag acaccgctgt gtgggatacc gcgcaggcaa aagataagat
     7261 ggatgcctgg ctgtctggcc cgaacgctaa caagattgag gtggttatcg cgaataacga
     7321 tgcgatggcg atgggcgcgg tagaggcgct gaaagcgcat aataaatcgt cgattccggt
     7381 ctttggcgtc gatgcgttac cggaagcttt ggcgctggtg aaatcgggcg cgatggccgg
     7441 tacggtactg aatgacgcca acaatcaggc gaaagcgaca ttcgatctgg cgaaaaacct
     7501 cgccgaaggc aagggcgcgg ctgacggcac cagctggaag attgagaaca aaatcgtgcg
     7561 cgtgccttat gtcggcgtgg acaaagacaa tctgagcgaa tttacccaaa aataactttt
     7621 ccgtctgtgg gcgcaatttt gttgcgccct gaaaccgtgg aagggtgacg tgccgcagac
     7681 cggataacgt atttcttttg ccatccggcg cggatagtca taattaaaaa ggccgacagg
     7741 gtatcattat gggcagcacg atctctccgt cgtcgggtga atatttgttg gaaatgcgtg
     7801 gcattaacaa atcatttccc ggcgtgaaag cgcttgataa tgtcaactta aacgttcgtc
     7861 cgcactctat tcatgcatta atgggcgaaa acggcgcagg caaatcaaca ttattaaaat
     7921 gtcttttcgg tatttatcaa aaagactccg gcagcattgt atttcaggga aaagaagtgg
     7981 acttccattc ggcgaaagaa gcgctggaga atgggatttc gatggtacac caggagttaa
     8041 acctggtatt acaacgttcg gtcatggata acatgtggct ggggcgttat cccaccaaag
     8101 gtatgtttgt cgaccaggat aaaatgtacc aggataccaa agcgatattt gatgagctgg
     8161 atatcgatat tgacccgcgc gcgcgtggga acgttatccg tttcgcaaat gcagatgatt
     8221 gaaattgcga aggcgttttc ctataacgct aagatcgtta ttatggatga accgacctca
     8281 tcgttaactg agaaagaggt taatcatctg ttcaccatta ttcgcaagct gaaagaacgc
     8341 ggctgcggca ttgtttatat ctcgcataaa atggaagaaa tttttcaatt gtgcgatgaa
     8401 attactatct tgcgcgacgg tcagtggatt gccacccagc cgctggaagg gctggatatg
     8461 gataagatca ttgcgatgat ggtcgggcgt tccctgaacc agcgctttcc ggataaagaa
     8521 aataagccgg gcgacgtgat tctggaggtt cgtcacctga cctcgctgcg ccagccttcc
     8581 attcgcgatg tctcctttga tttgcacaag ggcgaaattc tgggcattgc cggtctggtt
     8641 ggggcaaagc gtaccgatat cgtcgaaacg ctgtttggca ttcgtgagaa gtcgtccggg
     8701 acaatcactt tacatggcaa gaaaattaat aatcacactg cgaacgaagc gattaaccac
     8761 ggttttgcgc tggtgacgga agagcgtcgt tccaccggaa tttacgccta tctggatatc
     8821 ggatttaact cattaatttc gaatatccgt aattataaaa ataaagtggg gttactggat
     8881 aattcccgga tgaaaagcga cacccaatgg gtcattgatt ccatgcgggt aaaaacgccg
     8941 gggcatcgcg cgcaaattgg ttcactttcc ggcggcaatc agcaaaaggt gatcattggt
     9001 cgctggctat taacgcagcc ggaaatatta atgctggacg aaccgacccg cggcattgat
     9061 gtcggcgcaa aatttgaaat ttatcagctt attgcggaac tggcgaaaaa aggcaagggg
     9121 atcatcatta tatcttctga aatgccggag ctgttaggga ttaccgatcg tatcctggtg
     9181 atgagtaacg gtctcgtttc cggcattgtc gatactaaaa caacaacgca aaacgaaatt
     9241 ttgcgtcttg cttctttgca cctttaagat caggggctcc ttatgagtgc gttaaacaag
     9301 aaaagctttt tgacctggct gaaagagggc ggaatttacg tcgttctttt agtgctgctg
     9361 gcgattatta ttttccagga cccgactttt ttaagtttgc tgaatttaag taatattctg
     9421 acgcaatctt cggtacgtat tattatcgcg ctgggcgtgg cgggactcat cgtcacccag
     9481 gggacagacc tgtcggcggg gcgtcaggta gggctggcgg cggttgtggc ggcaacatta
     9541 ctgcaatcaa tggaaaacgc caacaaagtg tttccggaaa tggcgaccat gccgattgcg
     9601 ctggtcatcc tgattgtctg cgcgattggc gcggtgattg gcctggtgaa cggcatcatc
     9661 attgcttacc tgaacgtgac gccgtttatt accacgcttg gcacgatgat tatcgtttat
     9721 ggaatcaact ccctttacta tgactttgtc ggcgcttcgc ccatttccgg ctttgacagc
     9781 ggcttttcca cctttgcgca gggctttgtg gcgatgggca gtttccggct ctcctacatc
     9841 accttttacg ctctgattgc ggtagtgttt gtctgggtgc tgtggaataa gacccgcttt
     9901 ggtaaaaaca tttttgctat tggcggcaac ccggaagcgg cgaaagtttc tggcgtaaac
     9961 gtggcgctga acctgctgat gatttatgcg ctctccggcg tgttttatgc cttcggcggc
    10021 ttactggaag cagggcgtat tggttctgcc accaacaacc tcggctttat gtatgaactg
    10081 gatgcgattg ccgcgtgcgt ggtcgggggc gtatcgttta gcggcggagt ggggacggtc
    10141 ttcggcgtgg tgaccggcgt cattatcttt accgtcatca actatggcct gacctatatc
    10201 ggggtaaacc cgtactggca gtacattatc aaaggcggca ttatcatttt cgccgtggcg
    10261 ctggactcgc tgaaatacgc gcgtaagaag tagttatcca gacgtattac cttgcttatc
    10321 agataacccg gcgcagcgaa actgcgcgcc gggcttcata ccgtgagcta cagcgttaac
    10381 gcgtgttctt tttcgccttt tttaaatttg acctcgccta aatcaataca ggcgaccggg
    10441 cagacatgac cgcacagcag acaaccgacg catttttccg tattgcaatg cggcgtgtgg
    10501 ctgtgttcat cccactccat cgcctgatga ccgccgtcat agcaggagat atagcaacgt
    10561 ccgcagccga cgcatttctc ctgattaatc cgcggataga cgatatagct gcgatccagg
    10621 tcttccgccg ggataatatt gccattcgcc agcccgatca tctcctgtaa tgaggcaaat
    10681 ccctgatcgg ccagatagtg gctgaggccg ctcgccatat cttctacaat gcggtaaccg
    10741 tattgcataa tgcctgtcgt cacctgtagg gtcgccgcgc ccagcagcag aaattcggca
    10801 gcgtcttccc aggtttcaat gccgccgata ccgctaatcg ggaaatcgcg cagttcaggg
    10861 tgcattcgca actgctggat aaaacgcagc gcaatgggtt tcaccgcttt tcctgaataa
    10921 ccggagatgc tggatttacc gttaaccacc ggcatcccga ttttgcggtt caggtcgatg
    10981 ttagtaatgg atttcacggt gttgatggtg gcgataccgt cggccccgcc gcgtttggcg
    11041 gccagcgcga cttcacacat atcgccaata ttcggcgtca ttttcgccag cattggcaaa
    11101 gatgaaccgc gttttacggc gcggcagtat ttttcaacca gttccgggct ttgccctaca
    11161 tcgcttccca tggcgtgcga ggtcatctgc gggcaagaga agttacactc aatcatatcc
    11221 gcgccggctt cttcaaccag acgcgccagt tcctgccact gctgctcatt ttcccccatg
    11281 atggaagcaa tcagcacctt atccggataa tcctgtttta gccgtcgaat ggcggccaga
    11341 ttctcttcca gcggatgctc agcaatttgc tccatgtttt tgaaaccaat aaaaccggta
    11401 tcttctttcg tcaggtggtc aaaacgtgga gagacttcgt tggcaataaa aaaccaatgg
    11461 ttttaaaaac gatcccgccc cagccggtat cataggcttt ggcgcacatc tcataacaat
    11521 tgcctaccgg agaagaagaa aggcaaaacg gattgggaaa cttaacgccg caaaaggtaa
    11581 cagacaaatc ttttgttaac atgagcaggc ctcctctaaa taatgatgaa tagcctgagc
    11641 ggcttctttt ccggttttta ccgcataaac gacggtctta tcacctttaa caatatcgcc
    11701 agcggcaaag atcgccgggt cgtcggtttg ataattgtgc gtgtcgataa tattatgctg
    11761 cgcttttatc tccgcaaagt tatccagtcg cgcgtgctgc cccacggcca aaataatatt
    11821 ttccgcttcc agcgtcagtt ctcctgagtg gcgtacatgg tggaaggtca ctttatttcc
    11881 gctgacggcg acaggcgtaa aaccatcaat aatcgatacg cctaatgcct gcgtgctggt
    11941 aaattctttt tcgctggcgg ggaattcggc taattcttcc cgcgccacgc aggtgacgga
    12001 aggacagccg agaattttta acgtactggc gacatccatc gctacgtcgc cgccgccaat
    12061 aattaatgcg ctacgcggaa cgctaatatc gccgtcggcc tgacgggcgc gctgtaaaaa
    12121 atcaacggca atctctacgt gactggcttg ctcaaataac ggtaaatcag agccacagga
    12181 catcccgacg gtcatcagca cggcgcgata ttcggctttg agttgcgcaa gcgatagcga
    12241 cccgcccacg tcacaattac atttaatatt gacgcccatt tctacaatgc gggcaatttc
    12301 ctgatcgagt acgctttgcg gcagacgaaa tgccgggatg ccgtgacgca gccatccgcc
    12361 gggctgcggc tgtttttcgt aaatggtgac gtcatagcct aaatgtgtga gcgtcacgct
    12421 tgcctgcaaa cctgccggac ccgcgccaat aatcgcgact ttcccgcgtg ttttactccc
    12481 gggctgataa atctgcatgg cagtctgctg ttcaaaatcg gtaataaaac gttgcaggcg
    12541 tgcaatatca ataggtttat ctattccgga acgtgtacat ccgcgctggc ataatttttc
    12601 cgtcggacag actctggcgc agacggcgcc aagcgcatta ttttcccgga tagtttccgc
    12661 tgcgccttta aaattgcgaa agtaaataga acgaataaat ttccccggat cggtttgcgc
    12721 cgggcaagcc tgactacagg gcgcatcgtg acataataaa caacgggaag cctcttttat
    12781 tgccagtaat ggcgtaaaac caggcgtgag ttcatccaga taattttgtt gcggcatata
    12841 atcttcctta atgcttgaat aaattaaggc gaaacgcaaa taacgcgttt taatgatcta
    12901 aaatctaccg ccagcctaag cattgaaaga agggcattct gtgaaagaat tcacaaaaaa
    12961 atgaaaccag aatgcaaaac agcatttgt
//
LOCUS       DAJVKX010000126        12969 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.126, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000126 DAJVKX010000000
VERSION     DAJVKX010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12969
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.126"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(156..593)
                     /locus_tag="OPY25_003590"
     CDS             complement(156..593)
                     /locus_tag="OPY25_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2778 domain-containing protein"
                     /protein_id="HCS0929097.1"
                     /translation="MAVRLTFDGQKLTWPGIGIFKATTGLPDLQWPDKQCVPDAAIPE
                     GNYKLFIQFQGEAPIRNAADCDLGPSWGWSTIPRGQAAGTCEIYWANWGYNRIRLESA
                     DEKTRKACGGKRGGFYIHDSTKGYSHGCIEVEPVFFRILKQET"
     gene            complement(620..1036)
                     /locus_tag="OPY25_003591"
     CDS             complement(620..1036)
                     /locus_tag="OPY25_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2195 family protein"
                     /protein_id="HCS0929098.1"
                     /translation="MKKYAVEVLFMSACAGMFLPVFAWGGTDVNIDNPLAECVDIHPV
                     HRQEMDNLTILKTTVTLKKSTGECGCFSALISYTSLLAQDVEGYGRGSAYSLQEGNIS
                     LAKMQGRYPFSFVLSVDNQSVRDQKLALMIRCTPPL"
     gene            complement(1164..1625)
                     /locus_tag="OPY25_003592"
     CDS             complement(1164..1625)
                     /locus_tag="OPY25_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929099.1"
                     /translation="MPRKIMLVFFLFISEFCYAQAVVSEFNLSDINRGGMTKAQAEKL
                     LIIALKYQKYDLSLDGVFVDGDLQDKHGNPPHPGYYDFSLGYDTPTAGAIDYWGLFSV
                     SSQTGDIWEINKCERIIFPQLQKIQQEIMKKTGATFASEVVQRRGLGCTDE"
     gene            complement(1610..2080)
                     /locus_tag="OPY25_003593"
     CDS             complement(1610..2080)
                     /locus_tag="OPY25_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000528842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCS0929100.1"
                     /translation="MGNYDKACNNVGAVRFVQEHMKVCEIIAKELDVPVENILGLAAA
                     ESQYGTGRIARGYNNYFSLQAPASFQSGRVHPKDSNKTWVAIFSSFSVCARSFAVKYG
                     DAVRGKKDALVFSEALVAAGFNSGSHITGGTDNYARITAGIIIMVGRRIACPVK"
     gene            complement(2184..2657)
                     /locus_tag="OPY25_003594"
     CDS             complement(2184..2657)
                     /locus_tag="OPY25_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929101.1"
                     /translation="MLSKIVSLLLFTILSVSSYAQVLVSNIPVFDLAKLNQEGLAETQ
                     AQALLVLSLKNKKYNITLPSVFMDEALKNDQGKPFHSGYYSFGVGYDSPSVGATDIWG
                     LFSVSPKTGDIWEEYSCERISFPALQKIQQEIMKKTGATFASEVVQRRGLGCTDE"
     gene            complement(2642..3112)
                     /locus_tag="OPY25_003595"
     CDS             complement(2642..3112)
                     /locus_tag="OPY25_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCS0929102.1"
                     /translation="MGNYDKACNNTEAVRFIQKYKNDCEIIANQLEVPVEFILAVAAK
                     ESRYGQGRIATEYNNFFSMHGPAPLQLSKVHPQGSHDVWVATYTSFLNCAKSFAIRFG
                     SAVRKINDPKKFAQALIESRFNSGKSSNGGHTGYASELVAMIGMVKRRMACSVK"
     gene            complement(3155..3922)
                     /locus_tag="OPY25_003596"
     CDS             complement(3155..3922)
                     /locus_tag="OPY25_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2094 domain-containing protein"
                     /protein_id="HCS0929103.1"
                     /translation="MRRPAVVSAPAMFGRLPDQRDYVRWRVGAEEGRIWQDWLNRQTW
                     VGSGRHIVLPEGQTTDEERDGWMHLSPRGEHDMPAPEHHPLPWSFVMSPGFLPMGGTT
                     DWLTGVLMASRDSVGRPWPLVIYQRCGREWLDESLQETQGWLYWLARLAAQHITPDTM
                     RRGRLTEQADQLWAMWQPGPWWAQWLRGLRRTSQRSWELTGLPDEAPVVELPGVRYLP
                     WPGWPGKTLGQATPGQGWFWQQNSEGRYVDALRLAEK"
     gene            complement(3922..7783)
                     /gene="tssM"
                     /locus_tag="OPY25_003597"
                     /pseudo
     CDS             complement(3922..7783)
                     /gene="tssM"
                     /locus_tag="OPY25_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459283.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
     gene            complement(8020..8514)
                     /locus_tag="OPY25_003598"
     CDS             complement(8020..8514)
                     /locus_tag="OPY25_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929104.1"
                     /translation="MKPLFSVLKSNHNSSSFESPDFVDSKDFYAGIGYDQGKLGAQFE
                     NTCAARMSVALIKSGVKFKGRLLPIKEGKWKGRSIETGAKNLADILSQATVFGKPAVW
                     RDPTKFQTELGNKKGVVFFWKIDGYNGGSGSHIDLIEPTSAGAVCHSHCYFSCKQIWF
                     WELR"
     gene            complement(8546..9295)
                     /locus_tag="OPY25_003599"
     CDS             complement(8546..9295)
                     /locus_tag="OPY25_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001769329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929105.1"
                     /translation="MIKKSTYDVSHHSAICGVTGDYYRISATYHIKRSIRVFLIILCC
                     LLPGGVFAGSLINAGLISPDNVNLSIRDFLGFYASDNLQEKDNTLMYVLGVADATEGK
                     TWCGYGQVDSITINHTVLAWLDRYSVKKPDARASVLIEEALVKNFPCQGTEPSVKIAS
                     RSSPVLSLTPDALNLSGNDFFKFWVSGNQLDKLRAGIYLLGVEDATEKKLWCGYDLFK
                     TLTLNEIVYVFLKIKHIKNLILARLSLLWIN"
     gene            complement(9300..10601)
                     /gene="tssL"
                     /locus_tag="OPY25_003600"
     CDS             complement(9300..10601)
                     /gene="tssL"
                     /locus_tag="OPY25_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssL, long
                     form"
                     /protein_id="HCS0929106.1"
                     /translation="MTDSTLTPPAADMMSFLSTTPEHKDSEYETPVHTSQRTELNVIV
                     EDGPDSKLRLAEISAAANPLLAAARPLLCALAAMPAKLDAALVEPYRNLLVREMHLYQ
                     TLCDQANLRREHVLAVRYCLCTALDEAANNTTWGRRGVWAGKSLLVTFHGESEGGIKL
                     FQIIGRLAASFQEHGNVLEVIYHLLGLGFEGRYSVQPDGRKQLDNIRQQLLTQLSQRR
                     DPVMPALSPDFQGAISGRLRRMRRVPVWLSAGIALLAMLTLFGLYSHRMDVQTVTVQQ
                     HIDAIGIKLPPPVPVHKLRLKILLANEIARGLLTVDEDDQHSRVVFRGDAMFVPGQKT
                     VSDAIRPVINKAAREIARVGGAVTVTGHTDSQPIHSAEFPSNLVLSEKRAAEVAALLT
                     SGGVPAGRVHIVGKGDTVPVADNGSKAGRAKNRRVEILVVE"
     gene            complement(10598..11941)
                     /gene="tssK"
                     /locus_tag="OPY25_003601"
     CDS             complement(10598..11941)
                     /gene="tssK"
                     /locus_tag="OPY25_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HCS0929107.1"
                     /translation="MSWNDRVVWSEGQFLLPQMFQQQERYLEHVMHYRSLPLTPFFWG
                     FSHYNIDGEALNIGKLILKEASGIFPDGTPFNAPDHTPLPPPLTILPEHLNQQICLAV
                     PVRAPNSEETTFDNNPESLARFSVHEHDIRDANSLGRGAQLLQLSHLRLRLLPEKAVT
                     GAWIGLPLTRITGLNPDGRIDIDHDLIPPIINYQASSLMCTWLSWINDLIRMRADSLA
                     ERLTGSDNHGHEAAEVSDYLLLQILNRFEPLLTHLAKTPLAPEVLYRYLSELAGELST
                     YVRPQTRRPAEYKEYKHLTPYAGLKSLVDEVQFLLNAVLIRGAQRIELKEGTYGILNA
                     VVAPSDLADFSTLVLAIKASMPTDVLLQHFAAQTKIGPSDRLPELIRSHLPGLALQVL
                     PVPPRQIPFQAGYIYYDIRREGALWEHIARYGGMAMHTAGEFPGLETELWGVRDK"
     gene            complement(11945..12481)
                     /gene="tssJ"
                     /locus_tag="OPY25_003602"
     CDS             complement(11945..12481)
                     /gene="tssJ"
                     /locus_tag="OPY25_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HCS0929108.1"
                     /translation="MNEWRNPTRWLCAVAMPFALLLLSGCGSSDALPDLESQRLDLSV
                     KASDKVNPDNQKKAAPIEIRVYELKNDAAFTTADYWSLHDNDKSVLTDDLVRRDSFIL
                     RPGEEKKLRRPLNAQTTAIGVLAGYRNLAKSVWRVTYKIPEAPEKAWYSSFIPGKGKV
                     QLEAELEQSAIVITERDK"
     gene            complement(12548..>12969)
                     /locus_tag="OPY25_003603"
     CDS             complement(12548..>12969)
                     /locus_tag="OPY25_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HCS0929109.1"
                     /translation="NEIEVLSWRWNIHQESTMHAGSGLGSGKVSVTNLDFDHYIDRAS
                     PNLFKYCASGKHIPQAILVMRKAGGNPLEYLKYTFTDLIVAVVSPSGSHDGEIASRET
                     VELSFSTVKQEYVVQNQQGGSGGTITAGYDFKANKEI"
BASE COUNT         2939 a         3854 c         3127 g         3049 t
ORIGIN      
        1 tatctggcca ccattgtaat cattgtcaac cacagcacgt tcagacacga taatttgatc
       61 cggttttaac ggtattattg ttttgttcca ccattcgttt gctgaccaga aacatactta
      121 acattaaccg taaatatctt ttcaccattt tctttttacg tctcctgttt cagaatacgg
      181 aaaaacaccg gttccacttc aatacaacca tggctgtaac ctttggtgga atcatggata
      241 taaaaaccac cccgcttgcc cccacaggct tttcgggtct tctcatccgc tgattccagc
      301 cggatacggt tatatcccca gttcgcccag tatatctcac atgttccggc agcctggcct
      361 cgcggaatgg tactccagcc ccatgatggt cccagatcac aatccgcagc atttcttatc
      421 ggtgcctccc cctgaaactg aataaacaat ttataattcc cttccggtat cgccgcatcc
      481 ggcacacact gtttatctgg ccactgtaaa tccggtaacc ccgtggtcgc cttaaatatc
      541 ccgataccag gccatgtcag cttttgcccg tcaaaagtca gtcttactgc catcatcttc
      601 tccctgacta ttctgtgtat tacagcggtg gtgtacaacg tatcattagc gccagcttct
      661 gatcccgtac agactggtta tccaccgata atacaaagct gaaaggataa cgtccctgca
      721 tcttcgccag tgagatattc ccctcctgaa gggaatatgc acttccgcgt ccgtaaccct
      781 caacatcctg cgccagtaag ctggtatagc tgattaatgc tgagaaacag ccacattcac
      841 cggtactttt tttcagtgtg accgttgttt tcagaatggt aaggttatcc atttcctgac
      901 gatgaacggg atggatatcc acacactccg ccagcgggtt atcaatgttt acatctgttc
      961 cgccccaggc aaatacgggc aggaacattc ctgcacaggc agacataaac agaacctcta
     1021 cagcgtactt tttcacagca tctgacctct atttttttca tccaccagcc gcagtgcatc
     1081 catataccgc ccttcactgt tctgctgcca gaaccagcct tgccctggca ggtaacgtat
     1141 gcccggtaga tccaactatc ccactattca tctgtacagc ccagcccccg gcgctgtacc
     1201 acttcactgg caaatgtcgc gccagttttt ttcattattt cttgttgtat tttttgcaac
     1261 tgcggaaata taattctctc acatttattt atttcccata tatcaccagt ttgagaactt
     1321 actgaaaaca gcccccaata atctattgct ccggcagtcg gtgtatcata gccaaggcta
     1381 aaatcataat atcccggatg gggaggattt ccgtgtttat cctgcaaatc accgtcaaca
     1441 aaaacgccat ccagcgataa atcatatttt tgatatttaa gtgcaataat gagtagtttt
     1501 tctgcctgtg ctttcgtcat tccaccgcga tttatatctg acaaattaaa ttcagataca
     1561 accgcttggg cataacagaa ctcagatata aagagaaaaa aaacaagcat tattttacgg
     1621 ggcatgctat tctccgcccg accataataa ttattccagc agttatcctg gcgtaattat
     1681 ccgtaccacc agtaatatga gatcctgaat taaacccagc agctaccaga gcttcagaga
     1741 agaccagagc atcttttttc ccccgaacag cgtcaccata cttgacagca aaagatcgcg
     1801 cacaaactga aaacgaagaa aaaatagcca cccaagtttt gttactatcc tttggatgaa
     1861 cccgacctga ctgaaatgat gcaggagcct ggagagaaaa gtaattatta tatcccctgg
     1921 caatacgacc tgtaccatat tgactttcgg cagcagcaag acccagtata ttctctaccg
     1981 gtacgtcaag ctcttttgca attatctcac aaaccttcat gtgctcctgg acaaatctta
     2041 ccgcacccac gttattacac gctttatcat aattacccat ttcttcattc cttagcagat
     2101 gtttttaaaa cctccatgct cattatttct ccgccagcct tgcccttgca ggtaacgtat
     2161 gcccggtaga tccaactacc ccgctattca tctgtacagc ccagccctcg ccgttgcacc
     2221 acttcactgg caaatgtcgc gccagttttt ttcattattt cttgttgtat tttttgtagc
     2281 gccggaaatg atattctctc acatgaatat tcttcccaga tatcacctgt tttcggactg
     2341 acggaaaata atccccagat atccgtagca ccaacagaag gagagtcata gcccacacca
     2401 aagctataat atccagaatg aaatggctta ccctgatcat tttttaaggc ctcgtccata
     2461 aaaacgctag gcaatgtaat attatatttt ttatttttta atgataaaac caataatgcc
     2521 tgagcctgtg tctcggcaag cccttcctga tttaatttag ccaaatcaaa caccgggata
     2581 tttgatacaa gaacctgggc ataactgctc acggataaaa tagtaaacaa aagcaatgac
     2641 actattttac tgagcatgcc attctccgct taaccatacc aatcatagcc accagttcac
     2701 tggcgtatcc ggtatgtcct ccattactac ttttacctga attaaatcgt gactcaatca
     2761 atgcttgtgc aaatttttta ggatcgttta tctttctgac tgcactacca aacctgatgg
     2821 cgaatgattt cgcgcaattt aaaaaagacg tataggtggc aacccacacg tcgtgacttc
     2881 cctgaggatg aactttactc aactgcaatg gtgccggacc atgcattgaa aaaaaattat
     2941 tatattcagt tgcaatcctt ccctgcccat aacgactttc ctttgctgca accgccagta
     3001 taaactccac tggcacttca agttgattag cgattatctc acaatcattc ttatattttt
     3061 gaataaacct taccgcctct gtgttattac acgctttatc ataattaccc atttcttcat
     3121 tccttagcag atgtttttaa aaccaccatg ttcattattt ctccgccagt cgcagcgcat
     3181 ccacataccg cccttcactg ttctgctgcc agaaccagcc ttgccccggt gttgcctgcc
     3241 ccagcgtctt gcccggccag cccggccacg gcagataacg cacgcccggc agttctacta
     3301 ccggtgcttc atccggcagc ccggtcagtt cccagctgcg ctgcgatgta cgtcgtaacc
     3361 cgcgcagcca ctgcgcccac cacggccccg gctgccacat cgcccatagc tggtccgcct
     3421 gctccgtcag ccgcccgcgc cgcatcgtgt ccggcgtgat atgctgcgcc gccagcctcg
     3481 ccagccagta cagccagccc tgcgtctcct gcaaactctc gtccagccac tcccgaccgc
     3541 agcgctggta aatcaccagc ggccacgggc gtcccacgct atcccgtgac gccatcagca
     3601 ctccggtcag ccagtcagtc gtcccaccca tcggcaaaaa tcccggcgac atcacaaagc
     3661 tccacggcag cggatggtgt tccggcgcgg gcatatcatg ttcgccacgc ggcgacaggt
     3721 gcatccagcc gtcacgctct tcatcggtcg tctggccttc cggcaacacg atatgccgcc
     3781 cgctgcccac ccatgtctgg cggttcagcc agtcctgcca tattcgtccc tcttcagcgc
     3841 ccacccgcca gcgcacatag tcgcgctggt ccggcaacct gccgaacatc gccggggctg
     3901 ataccaccgc tggccggcgc attacaacgc cctcgccgga caactgaagt tctgcaacag
     3961 ctcccggctg accgggttaa aatcccgccc ggcagtgatt tccagcacca cccggcgacc
     4021 gtcaaaatca tattccacca attggcgccc ccgcaccgcc gtttcctgta cctttccggc
     4081 gtccagcaga tgaaacagcg cccacggccc gccggtcagt agcgttgagg tgtcctggcg
     4141 aatacgcggg ctggcggtga tttccgccat cgagccgttg cgcggtcccg gccacgtcac
     4201 tttcaggggc cggtccggac catgggcgta gcgcagcacc tgaccatcga tatcaatcac
     4261 cagttccgtg atggccgggt ccatatccac cacgctaatc tgcatcgacc aggaaaattt
     4321 tttcctgccc tcgctgttaa aaaacacgct gcggatctgc ttcgcctgct gaaacggcgt
     4381 taaatccggc ccctgcaatg tcatgttgcc ttcggtcggt ttgtagcgcc acgggtcgct
     4441 ggcggtgtcc gccagcggag ccagttgttt gctccagaaa gcatccagta cgccgccgct
     4501 ggcgaagatg cggttaaagt cctcggcgct gacctcctgc ggactatcgg cgaacggata
     4561 gcgcccgtcg atggcgtcac ggcagtcgtc gcccatcatc gcctccatct gggtgttgag
     4621 cacatcgccg gtcccggcgt tgattttgcg cgttccctgc ttcgtcagat ccagcaggat
     4681 gtttttcagc ggcgcaggca gtttcgccgc ctccagttgc aacttgtctg cggcagtaat
     4741 gcgcgctggc aacgtccccg ccgccagcgc gctgtcagca atggccagtt gggtgtaata
     4801 ctcgttgagc atggtcagca gcgaagcgat ctgcatcgtc ccaccgccgc tctgtccgcc
     4861 gtccgtccgc ccggcaatga cctcgcgcag cgcggcgaaa cggtcatcca ccagcgtttt
     4921 ttccagccgc tcttccgggt gaatatcctg gaacagtttt gccgtctgta ccactttccc
     4981 cgcgttaccg gacgcgcgct gcgccagttg tttctgtctg gcctgcgggt ccggcggcgg
     5041 caccagcgtg gtctgctcca ccaccgcttt tcccagccgc atcagcggtg agtccggcga
     5101 cgccagggtg cgcagcacct gtaaatcata ggccaggccg gaactgccct cttccccggc
     5161 actgttgata ctatggatac tgtccagaaa atcctgccag cggcgggcat attccgtcag
     5221 gtacaaacgg cggacttcgc gggcgacaga ctgctcctgc cccggtatct ggctgcgcag
     5281 gctgtcagtc agcttttttg gcgtactctc ccggcccatc acccagccat cgttcgccgt
     5341 cgccacaaat tccggtaatc gtttgtcgaa cagctcccgg taaccttcac gggtaaaaat
     5401 acccggcacg ccccgatcca gcggcgcgcc gttgctacgc acaaacaccg ttcccgcatc
     5461 cgcgccgacg gcgcgtacca gcgtgaactc ctgcggcgct tcgctctcca tcaccgccag
     5521 cgcccgcgca tagatacgct cggtactggt gtgaccgtcg aggaatgccc gcgcctggcg
     5581 gatcagcgcc tcatctttct catacggtga atgcaccacc cggctgccgt caaacagcgc
     5641 ttcgatatgc gtcagcacgg cggcgcgccc gccaaacccg gccacgctgt cgctgttccc
     5701 cagatcgtta atcacccacg actggatctc cgccgcgttg tatttatctt cgtgatcttt
     5761 atccagattc agtagcagat agatgcgcag ggcatcatac gcagctttac tgtcctgacg
     5821 ggcaatggcg tctgccagca catactccat ccgtttcacc agcggcggca gcagcagttg
     5881 atccagcaga cggttgtaca gcgacgccac gctgtcggtt accggcggta cgctgtacag
     5941 gccgtagcgc caggtcagcg gcggcgcgtc cgggtccagt cggccaggcg gacagttccc
     6001 ttgcgctgtc cagcagtgcc gggacgggag ccatcgccgg tttaccggtg taggctttca
     6061 catcaccgtc cagccgggtc gcgcgggcgc tgatttcatt cagatagtcg ccgttggtct
     6121 gctggctggt ctgcatcccc tgccacaaca ggaatgccag caccagtacc agcaggtgcc
     6181 cgccgaggcg cagcaggcgg taacgccagg cccactggag gtttggctcc accaggtgcg
     6241 cttcacggaa aataaactgt gtcagcaggt catgcagaaa gtagctgcgg ttgccgtccg
     6301 gcagagcgtg tgggagagag gcggatgatt cgccacgggt ggtttttatc gcccggacaa
     6361 agcgctgcca gatactcaac tggtcggcca cggcgtcggc ctgcgcctgc gcggcgctgg
     6421 tgaaaaacac cccgcgcagc gtgttattca gttgcgtggc atcgaatttt gaatcgagga
     6481 agatctgttc aatagcctcc agcaacggct cgccgagggc ggcgaactca cgcgggaagg
     6541 tatacagccg ctggcggctt ttaaggtcgt actcttcctg taaccgggta tccagtccct
     6601 gatccagccg cagcgtcagg cgcgccagct cctgcgcgca ggcggcatgc agcgcctgcg
     6661 ggtcgcccgt ttttcgcctg cggctgtacg gcaacgtaaa gccccagatt tgtgcgcgaa
     6721 gatggctggt cagcgtacga aaatactcgc tgaaccccgg caacaaatcc attttagtga
     6781 ccaccagata gaccggaaag cgaatcccca gggtctcgcg cagttctgcc agtcgcgccc
     6841 gcagagcggc gcaggccgcc aggcgttccg ccggtggctg tgcggttaaa tccgctacgt
     6901 ttagcgtcag gatcacgccg ttaagcggcg cgccggggcg atgtttacgc agcagaccga
     6961 gaaagccctg ccactctccg gcgttgcgct gcgcggcgct cgcttcgccg ccgtcatcgt
     7021 ggcgcgcgta gcgtccagcg gtatcaatca acaccgcttc gttggtaaac caccagtcgc
     7081 agtgtagcgt gccgccaccc ggcactgtca ggatgcgcga ggtctgctcc atttgctccg
     7141 ccagcgggaa ctgcaatccg gtgttcagca gggccgtggt tttgccgtcg ccgggactgc
     7201 cgaccaccat gaaccacggc agctcataca gaaagcgttt tccctcgaag attttacgcc
     7261 agccaggcat atccacccgc aactgccgca gctgccggat ggcctgcgtg acaatatggt
     7321 tgacggtgcg caggtcggct ttgatctcgc ctgccaccgg tacctcttcc ccgcgcggat
     7381 gcaggaagcg acgcagcagt tgttcatcca tacgcagcgc acgccacagc cggtacaggc
     7441 cgtacagcgc gtacatcagc aggatgaaac caatcagggt caggcggacc cacagcggcg
     7501 caaacggatg gacatcgccc agggccagca gcggtgtgac gaagccaatc gccaggcaca
     7561 ggacactgat gccgatgata ctcatcgacc agttgaccag ccacagtacc agcaacatca
     7621 gcaacagggc aatggtcacc acccggctgc ccacggaggc cagcgggcgc agggtatcaa
     7681 atgacaccag cggcccgaca aaccagacca gcagcgccag aaccagaacg cccacaatcg
     7741 ccagcgcgcg ccgggaaaaa agcagactga gaaatttttg cattatattt cgactcgcca
     7801 cccaataatc agtaacagca aagcgctgag accagaaaac aatctcccgt taccgtaatt
     7861 aatttaaaaa aaatatagaa agctcttgaa aaataataaa tccggaagtc aaaaatactt
     7921 cacggaccct gaacgtgtgt tttcgtctct caactcttca gaattccggc attattacat
     7981 tccatttcac tcaaatcaca cgaacggaat ttcagaattt tagcgtaatt cccagaacca
     8041 aatttgctta caggaaaaat aacagtgtga atgacatact gccccggcac tggtcggctc
     8101 aatcagatcg atatgactac cactcccacc attatatcca tcaattttcc agaagaagac
     8161 cacacctttt ttattaccca gttctgtctg aaatttagtc ggatcacgcc agaccgcagg
     8221 tttaccgaaa acagttgcct gcgaaagtat atctgccaga tttttagcgc ctgtttcaat
     8281 gctccggccc ttccacttgc cctcttttat cgggagaaga cggcctttaa acttcacacc
     8341 tgatttaatt aatgccacgc tcatacgggc cgcacaggta ttttcaaact gagcaccaag
     8401 tttcccctgg tcataaccaa tgcctgcata gaaatctttc gaatcaacaa aatcaggact
     8461 ttcaaaagat gatgaattat gattagactt tagcactgag aataaaggtt tcatttttta
     8521 actcctgtat cacatgaata tttaattaat ttatccataa taagctcagc cgcgcgagaa
     8581 ttaagttctt tatgtgtttt atttttaaga aaacatagac aatttcattt aatgttagcg
     8641 tcttaaataa atcgtatcca caccatagtt ttttctccgt tgcatcctcc acgccaagca
     8701 gatagatacc cgccctgagt ttatccagtt gattaccaga tacccaaaat ttaaaaaagt
     8761 cattacctga aagattaagc gcatccggcg tcagggataa cacaggagat gaccgggaag
     8821 caatttttac ggagggttca gtcccctgac aggggaaatt tttaactaat gcttcctcta
     8881 tcagcaccga agctcttgca tcaggctttt tcacagagta ccgatcaagc caggccagca
     8941 cagtatggtt tattgttata ctgtcaacct gaccatatcc acaccacgtc ttaccttctg
     9001 tggcatccgc tacccccaac acatacatca gtgtattatc tttttcctgt aagttatcac
     9061 tggcataaaa ccccagaaaa tcccgtatac tgaggttgac attatcgggg gaaattaatc
     9121 ctgcgttaat cagggacccg gcaaaaacgc caccgggtaa caggcaacat aagatgatca
     9181 aaaaaacacg gatagatcgt tttatgtgat atgtcgctga gatccgataa taatcccccg
     9241 tcacgccaca tattgccgaa tgatgagaca catcataggt cgattttttt atcattcatt
     9301 cactccacta ccagaatttc cacccgacgg tttttcgccc gcccggcttt actgccgtta
     9361 tccgccaccg gcaccgtatc gcccttgccg acgatatgta cccgtccggc aggtacgccg
     9421 ccggaggtca gcaacgccgc aacttccgcc gcccgttttt ccgatagcac caggttggat
     9481 gggaattcag ccgaatgaat gggctggctg tcagtgtgac ccgttacagt gactgcgccg
     9541 cccacgcggg cgatttcccg cgccgctttg ttaatcactg gccggattgc gtcactcacc
     9601 gttttttgtc ccggtacaaa catggcgtcg ccacggaaga ccaccctact gtgctggtca
     9661 tcttcgtcca cggtcagcag gccacgggcg atttcgtttg ccagcaggat tttcagccgc
     9721 agcttatgaa ccggcacggg cggcggcagt tttataccaa tcgcatcaat atgctgttgt
     9781 acggtgacgg tctgcacatc catccggtgg ctgtaaaggc caaacagcgt cagcatcgcc
     9841 aacagggcta tcccggcgct cagccagacc ggcacccggc gcatccgccg cagtcgtccg
     9901 cttatcgccc cctgaaagtc aggcgagagc gcgggcatga ccggatcgcg acgctgtgaa
     9961 agctgtgtca gcagttgctg acgaatattg tccagttgct tacgcccgtc tggctgcacg
    10021 ctgtagcggc cttcaaatcc cagccccagc aggtggtaga taacctccag tacgttgcca
    10081 tgttcctgga agctggccgc cagacgcccg atgatctgga aaagttttat cccgccttcg
    10141 ctttcaccat gaaatgttac cagcaggctt tttccggccc agacgccgcg ccgcccccag
    10201 gttgtgttat tggcggcttc atcaagcgcc gtacacaggc agtaacgtac cgccagtacg
    10261 tgctcgcgcc gcaggttcgc ctgatcgcat aatgtctggt acagatgcat ctcgcgtacc
    10321 agcagattac ggtaaggctc taccagggcc gcatccagtt tagcgggcat ggctgcgaga
    10381 gcgcacaata aaggccgggc agcggcgagc aacgggttag ccgccgcgct gatttcagcc
    10441 agccggagtt tgctgtccgg accgtcttca acgatgacat tgagttccgt gcgctggctg
    10501 gtgtgtaccg gcgtttcata ttcactgtcc ttatgttccg gcgtggtgga caaaaaggac
    10561 atcatgtccg ccgctggcgg cgtcagggta ctgtctgtca tttatcgcgc actccccaca
    10621 gttctgtctc cagccccgga aattccccgg cggtatgcat ggccatcccg ccgtaacggg
    10681 caatgtgttc ccacaatgct ccctcgcggc ggatgtcgta atagatgtat ccggcctgaa
    10741 acgggatttg gcgcggtggt acaggcagaa cctgcaaagc cagccccggc agatgcgagc
    10801 ggatcagttc cggcaggcga tcggatggcc cgattttggt ctgggcggca aaatgttgca
    10861 gtagcacatc ggtcggcatt gaagccttta tcgccagtac cagcgtgctg aaatcggcaa
    10921 gatcggaagg ggccaccacc gcattcagga taccgtaagt cccctctttc agctcgatgc
    10981 gctgcgcgcc ccggatcagt accgcgttca gcaggaactg cacctcatca accagcgatt
    11041 tcaacccggc atagggcgtc aggtgtttgt actctttgta ttcagcgggc cgtcgcgttt
    11101 gtggacgcac ataggtggag agttccccgg ccagttcgga caggtagcga tacaacactt
    11161 ccggggccag cggggttttc gccaggtgag tcagcagcgg ctcaaagcga ttgagaattt
    11221 gcagcagcag gtaatcggag acctccgctg cttcatggcc gtggttgtcg ctgccggtca
    11281 gccgttccgc cagcgaatcg gcccgcatcc ggatgagatc gttgatccac gacagccagg
    11341 tacacatcag tgaactggcc tgataattaa tgatgggcgg gatcaggtcg tggtcgatat
    11401 ctatccgccc gtcagggttc aacccggtga tgcgggtcaa cggcaggcca atccaggcgc
    11461 ccgtcaccgc cttttccggc agcagccgca ggcgcagatg actgagctgt aataactgcg
    11521 cgccacgtcc cagcgagttg gcgtcgcgga tgtcgtgttc atgtaccgag aaacgcgcca
    11581 gtgattccgg gttattgtca aacgtggttt cttcgctgtt cggcgcgcgt accggtaccg
    11641 ccagacaaat ctgctggttc aggtgctccg gcaggatggt cagcggcggc ggcagcgggg
    11701 tgtggtccgg tgcgttaaac ggcgtgccgt caggaaaaat ccctgatgcc tctttcagta
    11761 tcagtttacc gatgttcagc gcttcgccat caatattgta gtggctgaat ccccagaaaa
    11821 agggagtcag cggcaggctg cggtaatgca tgacgtgttc cagataacgc tcttgctgct
    11881 gaaacatctg cggcagtaaa aattgtcctt cactccagac tacgcggtca ttccagctca
    11941 taattcattt atcccgttcc gtaattacaa tggcgctttg ttccagttcc gcctccaact
    12001 gcacttttcc tttccccggt atgaagctgc tgtaccaggc tttttccggg gcttccggga
    12061 ttttgtaggt tacccgccag accgatttgg ccaggttacg gtatccggcc agtacgccga
    12121 ttgccgtggt ctgcgcattc agcgggcgac gcagtttttt ctcttcgccg ggacgcaaaa
    12181 taaagctgtc gcgacgcact aaatcgtcgg taaggacgga tttgtcgttg tcatggagcg
    12241 accagtaatc agctgtcgtg aaagcggcgt cattttttag ttcataaaca cgtatctcaa
    12301 tgggcgcggc cttcttctga ttgtcaggat tcaccttatc ggaggctttc acgctcaggt
    12361 cgagtcgctg tgattcgagg tcaggtaacg catcgctact gccgcatccg gaaagcagga
    12421 gcagtgcaaa aggcatagct accgcacata accaccgagt ggggttacgc cattcattca
    12481 ctgtaaattc ctttaaaatc aaaacaataa atccggccag atataaatct ggccggaaaa
    12541 acagccgtta aatttctttg ttcgccttga agtcgtaacc tgcggtgata gtgccgccgc
    12601 tgccgccctg ctggttctgc accacgtatt cctgtttcac agtgctgaaa gaaagctcga
    12661 ccgtttcacg ggaggcgatt tcaccatcgt ggctgccgct cggggaaacc acggcgacaa
    12721 tcaggtcggt gaaggtatac ttgaggtact ccagcggatt gccgccagcc ttacgcataa
    12781 ccagaatggc ctgcggaatg tgcttgccgg aggcgcagta tttgaacagg ttcgggctgg
    12841 cgcgatcgat atagtgatca aaatccagat tagtgacgga gaccttaccg gagccgaggc
    12901 cgctaccggc gtgcatggtg gattcctgat gaatattcca gcgccagctc agtacttcaa
    12961 tttcatttt
//
LOCUS       DAJVKX010000127        12959 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.127, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000127 DAJVKX010000000
VERSION     DAJVKX010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12959
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.127"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            47..1021
                     /gene="cysB"
                     /locus_tag="OPY25_003604"
     CDS             47..1021
                     /gene="cysB"
                     /locus_tag="OPY25_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HCS0929110.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFARSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIATEALHLYDDLVM
                     LPCYHWNRSIVVTPDHPLAATSSITIEALAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPLTDPDLVRIDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDTAVALRSNEEIEAMFQDIKLPEK"
     gene            1281..1442
                     /locus_tag="OPY25_003605"
     CDS             1281..1442
                     /locus_tag="OPY25_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001308615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HCS0929111.1"
                     /translation="MISDTDSMRLVMPSENQEPRRDPELKRKAWLAVFVGSALFWVVV
                     ALVIWHWWG"
     gene            1443..1613
                     /locus_tag="OPY25_003606"
     CDS             1443..1613
                     /locus_tag="OPY25_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929112.1"
                     /translation="MSITSERERVVAPPIQSGDDDNTPDTTVFRSVPQHWTLTPQQRA
                     FIDAFADEVSQK"
     gene            1998..4673
                     /gene="acnA"
                     /locus_tag="OPY25_003607"
     CDS             1998..4673
                     /gene="acnA"
                     /locus_tag="OPY25_003607"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HCS0929113.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDIARLPKSLKV
                     LLENLLRWQDGESVTDEDIQALAGWLKNAHADREIAWRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTSKVNPLSPVDLVIDHSVTVDHFGDDDAFEENVRLEMERNHERYMFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAIWSELQDGEWIAYPDSLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAITLEYMRLSGRSD
                     DLIELVETYAKAQGMWRNPGDEPVFTSTLELDMGDVEASLAGPKRPQDRVALGDVPKA
                     FAASAELELNTAQRDRQPVDYTMNGQPYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAQAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPEPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLVSPPLVVAYALAGNMNI
                     NLATDPLGYDRKGDPVYLKDIWPSAQEIARAVELVSSDMFRKEYAEVFEGTEEWKSIQ
                     VESSDTYGWQSDSTYIRLSPFFDEMQAQPAPVKDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQNHGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMLPGVEGGMTR
                     HLPGTEAMSIYDAAMLYQQEKTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSSLIGMGILPLEFPQGVTRKTLGLTGEEVIDIADLQNLRPGATIPVMLTRADG
                     SKETVPCRCRIDTATELTYYQNDGILHYVIRNMLN"
     gene            complement(4729..5319)
                     /gene="ribA"
                     /locus_tag="OPY25_003608"
     CDS             complement(4729..5319)
                     /gene="ribA"
                     /locus_tag="OPY25_003608"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HCS0929114.1"
                     /translation="MQLKRVAEAKLPTPLGDFLMVGFEELATGHDHAALVFGDISGKT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTHIAEEGRGILIYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVDEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAAKMGHLLSK"
     gene            5515..6279
                     /gene="pgpB"
                     /locus_tag="OPY25_003609"
     CDS             5515..6279
                     /gene="pgpB"
                     /locus_tag="OPY25_003609"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HCS0929115.1"
                     /translation="MLSIARRTAAGAALLLIMPLAVWVSGWQWQPGHQVWWLKTLFWI
                     TETVTKPWGVITHVILCGWFLWCLRFRLRAAIMLFAILGGAIIVGQGVKSWVKERVQE
                     PRPFVVWLEKTHHIPVDEFYTLKRTERGHLVKEQLAGQQNIPVFLRQHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTFTIAFLLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWLLVTLATWLAQRICGPLMPPREEAQEIAEREQES"
     gene            6429..6737
                     /locus_tag="OPY25_003610"
     CDS             6429..6737
                     /locus_tag="OPY25_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LapA family protein"
                     /protein_id="HCS0929116.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAVGFAIGWLICGLFWLRVRVSLARAERKIKRLENKLSPATDVAVPADSSVVKE
                     "
     gene            6744..7913
                     /gene="lapB"
                     /locus_tag="OPY25_003611"
     CDS             6744..7913
                     /gene="lapB"
                     /locus_tag="OPY25_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HCS0929117.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQTKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAVQQLGRDYMAAGLYDRAEDMFNQLTDETEFRVGALQQLLQIYQLTSDWQKA
                     IEVAERLVKLGKDKQRIEIAHFYCELALQQMGNDDMDRAMALLKKGAAADKNSARVSI
                     MMGRVYMARGDYAKAVESLQRVIVQDKELVSETLEMLQTCYQQLGKNAEWAEFLRRAV
                     EENTGAGAELMLADILEAREGSDAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEQVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGQ"
     gene            8104..8841
                     /gene="pyrF"
                     /locus_tag="OPY25_003612"
     CDS             8104..8841
                     /gene="pyrF"
                     /locus_tag="OPY25_003612"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HCS0929118.1"
                     /translation="MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASG
                     GARMMAAARDALAPFSKDAPLLIAVTVLTSMGTSDLHDLGVTLSPAEHAERLARLTQQ
                     CGLDGVVCSAQEAVRFKQAFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYM
                     VIGRPVTQSVDPAQTLKDINASLKREA"
     gene            8841..9167
                     /gene="yciH"
                     /locus_tag="OPY25_003613"
     CDS             8841..9167
                     /gene="yciH"
                     /locus_tag="OPY25_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HCS0929119.1"
                     /translation="MSDSNSRLVYSTQTGRIEEPKTAPVRPKGDGIVRIQRQTSGRKG
                     KGVCLITGIEMNDAELTKLAAELKKKCGCGGAVKEGIIEIQGDKRDLIKSLLEAKGMK
                     VKLAGG"
     gene            complement(9287..9505)
                     /gene="osmB"
                     /locus_tag="OPY25_003614"
     CDS             complement(9287..9505)
                     /gene="osmB"
                     /locus_tag="OPY25_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HCS0929120.1"
                     /translation="MFMMSKKMAAAVLAITVAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(9766..10518)
                     /locus_tag="OPY25_003615"
     CDS             complement(9766..10518)
                     /locus_tag="OPY25_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0929121.1"
                     /translation="MNSRQQSILQMVVDKGQMSVAELAKITGVSEVTIRQDLNTLEKQ
                     SYLRRAHGFAVSLESDDVETRMMTNYTLKRRLAEFAASLVSPGESVFIENGSSNALLA
                     RTLAEQKDVTIITVSSYIAHLLKETPCEVILLGGIYQKKSESMVGPLTRQFIHQVHFS
                     KAFIGIDGWQADTGFTGRDMMRSDVVNAVLEKGSEAIVLTDSSKFGCVHPYPLGPLSR
                     FHRVITDSKISASDQMQLEHAGLLVNVIGSSV"
     gene            complement(10605..10784)
                     /locus_tag="OPY25_003616"
     CDS             complement(10605..10784)
                     /locus_tag="OPY25_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929122.1"
                     /translation="MSDIEAQRIAARIDTVLDILVAGDYHSAINNLEILRAELLDQVK
                     DGISPSQAPGSPWEI"
     gene            complement(10906..12888)
                     /gene="pdeR"
                     /locus_tag="OPY25_003617"
     CDS             complement(10906..12888)
                     /gene="pdeR"
                     /locus_tag="OPY25_003617"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HCS0929123.1"
                     /translation="MMKQIQEQTALNPLHSHWRLADDRNVLYLSPTGETDAEKTVELS
                     PEQAGRIREITAITSSLLITLLIEKQVTAVHLVGRKINNREWAGSLATWPDTPAVAPT
                     QAQELSFAEQIVSEANSVIAILDSRGKICRFNRLCEEYTGLKERDVIGQSVFKLFMSR
                     REAVASRHYIENFFRNGNAYEIERWIKTRKGQRLFLFRNKFVHNGSGKNEIFLICAGT
                     DITEERRAQERLRILANTDTVTGLPNRNAIHEFINHAIASAGESQVGIVYLDLDNFKK
                     INDAYGHMFGDQLLQAVSLALLSCLEEDQLLARLGGDEFIVLVAHTSQAALEAVASRI
                     LTRLRQPFRIGLIEVYTGCAIGISLAPRHGQDSESLIRTADTAMYNAKEGGRGQFCVF
                     SPEMNQRVFDYHWLDTNLRKALENDQLLIHYQPKITWRGEVRSLEALVRWQSPERGLI
                     PPLEFISYAEESGLIVPLGRWVILDVVRQIAKWRDKGINLRVAVNFSARQLADQTLFT
                     ALKQALYDLNFEYCPIDVELTESCLIENDTLALSVIQQFSQLGAQIHLDDFGTGYSSL
                     SQLARFPIDAVKLDQAFVRDIHKQPLSQSLVRAIVAVAQALNLQVIAEGVENAKEDAF
                     LTKNGVNERQGFLFAKPMPAVSFERWYKRYQTKKMR"
BASE COUNT         3067 a         3139 c         3497 g         3256 t
ORIGIN      
        1 ctgcagataa acgatggcct gatggcgcta atctggatga tgtattatga aattgcagca
       61 gcttcgttac attgttgaag tggttaatca taaccttaac gtctcctcta ccgctgaggg
      121 gttgtatact tcccagccgg ggatcagcaa gcaggttagg atgctggaag atgagcttgg
      181 catccagatt ttcgcccgca gtggtaagca tctgactcag gtgacgcccg caggtcagga
      241 gattattcgt attgcgcgtg aggtgctttc caaagtcgat gccattaagt cggtcgccgg
      301 cgagcacacc tggccggata aaggctcgct ctatattgcc actacccata ctcaggcgcg
      361 ttacgcattg ccaggcgtga ttaaaggctt catcgagcgt tacccgcgcg tttcgctgca
      421 tatgcaccag gggtcgccaa cgcagattgc ggaagcggta tcgaaaggga acgccgattt
      481 cgcgattgcc acggaagcgc tgcatttata tgacgatctg gtgatgttgc catgctatca
      541 ctggaaccgt tcgatagtgg tgacgccgga tcatccattg gcggcaacgt cttccataac
      601 gatcgaagcg ctggcgcagt atccgctggt gacgtatacc ttcggcttta ccgggcgttc
      661 cgaactggat accgctttta atcgcgcagg gttaacgccg cggatcgtct ttactgcaac
      721 cgatgcggat gtgattaaaa cgtatgtcag gttggggctg ggcgttggcg tcattgccag
      781 catggcggtc gatccgctta ccgatcctga tttagtgcgg attgacgcgc acgatatttt
      841 tagccacagc accacaaaaa ttggttttcg ccgtagtact tttttacgca gctatatgta
      901 tgattttatc cagcgttttg cgccacatct gacgcgtgat gtggtggata cggcggtggc
      961 gttgcgttct aatgaagaaa ttgaagcgat gtttcaggat ataaagctgc ctgaaaagta
     1021 atatcaccgt gggtttgtgt cgtagtggca tggcagacaa agccgccttt tgcaatatcc
     1081 ctcgaagtat tacgggtaat gatcagcaaa atagtgttga attacccgtc ccgccagttt
     1141 ctttttccaa atagttatct tgagtcaaaa gattgattta ttcactggca acgattcgta
     1201 aattgactgg atttttgact aaagtttatt taggatttgt ctcatctgat gattaattgt
     1261 accgattgtt tggtgctgaa atgataagtg ataccgatag catgaggtta gtaatgcctt
     1321 ctgaaaacca ggaaccgcgc cgcgaccctg agctcaaacg taaagcatgg ctggcggttt
     1381 ttgtgggttc tgcgttgttc tgggtagtgg tagcgcttgt tatctggcat tggtggggct
     1441 aagtgagcat tacgtcggaa cgcgagcgcg tggtcgcgcc cccgattcaa tctggtgacg
     1501 atgataacac cccggatacg accgtttttc ggtctgttcc gcaacactgg acgctcacac
     1561 cgcagcagcg ggcatttatt gatgcttttg ctgacgaggt gtcacaaaaa taatattcgt
     1621 ctttttattg gcgttactgt tttattaacg ctgtcttatt acaccgcagc aaccgtgtgc
     1681 tgagcgcttc tcagtattga ttaaacacag ttggtgttgc ctatgttaac gtcaaatata
     1741 aagtattggt catggactgg cgcgtttata ttatcgctac tgttctgggc cgagttaatc
     1801 tggattgccg tctaatctcg tcaaagcccg ataatgcgtt atttatcggg ctttttcatc
     1861 ttcgttcctc gcctgttagg tttctcctct tttagcaatt tgggttgtta tcaaaacgtt
     1921 acattttgtt tgtgttatct ttaatacaac cctgtggaga atcagggtaa cgcaaccctg
     1981 tcattaaagg aggagctatg tcgtcaaccc tacgagaagc cagtaaggat acattgcagg
     2041 ccaaagataa aacgtatcat tactacagtc tgccgctggc tgccaaatcc ctgggcgata
     2101 tcgcccgttt gcccaaatca cttaaagtgt tactggaaaa cctgttgcgc tggcaggacg
     2161 gcgaatctgt gactgatgaa gatattcagg cgctggccgg ttggcttaaa aatgcccatg
     2221 ccgatcgtga aattgcttgg cggcccgccc gtgtcctgat gcaggacttt accggcgtgc
     2281 ctgccgttgt cgacctggcg gcgatgcgtg aagccgttaa acgcctcggc ggcgatacgt
     2341 cgaaagtgaa cccgttatcg ccggttgatc tggttattga ccactctgtg acggtcgatc
     2401 atttcggcga tgatgatgcg tttgaagaaa acgtgcggct ggaaatggaa cgtaaccatg
     2461 agcgttatat gttcctgaaa tggggaaagc aggcattcag ccgtttcagc gtggtgccgc
     2521 ccggcaccgg catttgccat caggttaacc tggaatacct gggtaaagcc atctggagcg
     2581 aattacagga cggggagtgg attgcttacc cggactcgct ggtggggact gactcccata
     2641 cgaccatgat taatggtctg ggcgtattgg ggtggggcgt gggtggtatt gaagcggaag
     2701 cggcgatgct tggtcagccc gtgtcgatgc ttatcccgga tgtcgtcggc tttaagttaa
     2761 ccggtaaact tcgggagggg atcactgcca ctgacctggt gctaaccgtc acgcaaatgc
     2821 tgcgtaagca tggcgtcgtg ggtaaatttg ttgaatttta tggtgacggt ctggattcgc
     2881 tgccgttggc ggatcgcgcg actatcgcta atatgtcgcc ggaatatggc gccacctgtg
     2941 gtttcttccc cattgacgcc atcaccttgg aatatatgcg attaagcgga cgtagcgacg
     3001 atctgatcga gctggttgaa acctacgcga aggcgcaggg aatgtggcgt aatcccggtg
     3061 acgaaccggt atttaccagt acgctggaac tggatatggg cgatgtcgag gccagcctgg
     3121 ccgggccgaa acgcccgcag gatcgcgtgg cgttaggcga tgtgccgaaa gcctttgccg
     3181 ccagcgccga gctggagctg aataccgcgc aaagagatcg ccagccggtt gactatacga
     3241 tgaacggaca gccatatcag cttccggatg gcgctgtcgt cattgccgcc atcacctcct
     3301 gtacgaatac ctcgaatccc agcgtgctga tggcggcggg attactggcg aaaaaggcag
     3361 taacgctggg gttgaagcgt caaccgtggg tcaaggcttc tctggcgccg gggtcaaaag
     3421 tggtatctga ctatctggcg caggccaaac ttacgcctta tctggatgag ctcggtttta
     3481 acctggtcgg ctatggctgt acgacctgta tcgggaactc cggtccgttg ccggagccta
     3541 ttgagaccgc gattaaaaaa ggcgatctga cggtaggggc cgtgctttcc ggtaaccgaa
     3601 attttgaagg gcgtatccat ccgctggtga aaacgaactg gctggtgtcg ccgccgctgg
     3661 tggtcgcgta tgcgctggcc ggaaacatga atattaacct cgcgacagac ccgctggggt
     3721 acgatcgtaa aggcgatccg gtatacctga aggatatctg gccttcggcg caggaaattg
     3781 cccgcgccgt tgaactggta tcatcggata tgttccgtaa agagtatgcg gaagtgtttg
     3841 agggcacgga agaatggaaa tcgattcagg ttgaatcgtc cgatacctac ggctggcagt
     3901 cggattcaac ctatatccgc ctgtcgcctt tctttgatga aatgcaggcc cagcctgcac
     3961 ccgtcaaaga tatccacggc gcgcgtatcc tggcgatgct gggcgattcg gtgacgaccg
     4021 accatatttc cccggccggc agtatcaagc cggacagtcc cgccggacgc tatctgcaaa
     4081 accacggcgt tgagcggaag gattttaact cctatggatc acggcgcggc aaccatgaag
     4141 tgatgatgcg cggtacgttc gccaatattc gtattcgcaa cgaaatgctg cccggcgtcg
     4201 aaggtgggat gacgcggcat ttgccgggta cggaagcgat gtcgatttat gatgccgcga
     4261 tgctctacca gcaggaaaaa acgccgctgg cggtaattgc cgggaaagag tatgggtcgg
     4321 gatcgagccg tgactgggcg gcaaaaggtc cgcggctgtt aggtattcgc gtggtgatcg
     4381 ccgagtcgtt cgaacgtatc catcgctcaa gcctgattgg gatggggatc ctgccgctgg
     4441 agtttccaca gggcgtaacg cgtaaaacgc tgggactgac cggggaagag gtgattgata
     4501 tcgcggatct gcaaaatctg cgccctggcg cgaccattcc ggttatgtta acgagagcgg
     4561 acggcagcaa agaaacggtg ccttgtcgct gtcgcattga taccgccacc gagctgactt
     4621 actaccagaa tgacggcata ttgcactatg tcattagaaa tatgctgaac taaagccgtt
     4681 tatcgggcct gccgtaaaca ggcaggcccg cgctttaata ccggtggctt acttgcttag
     4741 caggtggccc attttggccg ctttagtatc gagataatgc tcattatttg gattacgacc
     4801 cacaatgagc ggaacgcgtt ccacgatatt aattcccgcc tcggtcagta tttcgacttt
     4861 cttcggatta ttggtcagta ggcgaacttc atccacgccg agtaatttga acatatccgc
     4921 gcacagggtg aaatcacgct catcggcggc aaagccgagc tgatgattgg cctccaccgt
     4981 gtcatagcct tgatcctgta acgcataagc gcgaatttta ttaagcaggc cgatattgcg
     5041 gccttcctga cggtggtaaa tcagaatacc gcgtccttct tccgcaatat gcgtcagcgc
     5101 ggcttccagt tgaaaaccac aatcacagcg cagactaaaa agcgcgtccc cggtaagaca
     5161 ttcggaatga acgcgagcca gtactggcgt tttacctgaa atatcgccaa aaaccagcgc
     5221 ggcatggtcg tgtccggttg ccagttcttc aaatcccacc atcagaaagt cacccaatgg
     5281 ggttggcagt ttggcttctg ccacacgttt aagctgcatg tatttctcca gattatgctg
     5341 acgcctgcgg tgtcgtcgcc tgttggcctg tatcccgcta ttttgccata aggcggcggt
     5401 catcacctaa tcactaccac gtaattgctc aggaatggca caaatttgtc aattttccag
     5461 tccggcgaga attttcagtt atgattgtga tacttactta taaaaggagc atccatgctt
     5521 tcaattgcga ggcgcaccgc ggcaggcgcc gccctgttgc ttatcatgcc gcttgccgta
     5581 tgggtatcag gctggcagtg gcagccagga catcaggtct ggtggctaaa aacgctattc
     5641 tggataacgg aaaccgtgac caaaccctgg ggcgttatca cgcatgtgat tctttgtgga
     5701 tggttcttat ggtgcctgcg atttcgcctg cgcgccgcca ttatgctgtt tgcgattctc
     5761 ggtggggcga ttatcgtcgg gcagggcgtg aagtcatggg taaaggagcg cgtacaggag
     5821 ccgcggccat ttgtggtctg gcttgaaaaa acgcaccata ttcccgtcga tgagttctac
     5881 actttaaagc gtacagaacg cggacattta gtgaaagagc agttggccgg gcaacagaac
     5941 atccccgttt tcctgcgtca gcactggcaa aaagagacgg gctttgcgtt tccctccgga
     6001 cacaccatgt ttgcagcgag ctgggcgctt ttggccgtgg gtctgttatg gccgcgcaga
     6061 cggactttca ccatcgcgtt tttgttagtc tgggcgaccg gcgtaatggg cagccgtttg
     6121 cttctgggaa tgcactggcc gcgagattta gtggtcgcca cgctcatctc ctggctatta
     6181 gttaccctgg cgacctggct ggcgcagcga atttgcgggc cgcttatgcc gcctcgcgaa
     6241 gaagcgcaag aaattgctga acgcgagcag gaaagctgac aacggttgat tttctgacta
     6301 ttgcccttaa atcatctgat ggtgggcgca tttccatttc gcgcgaggcg ggaaaatggt
     6361 aatttagaag gctggatgcg gtaagttgga cacgatttat tcgcgcaaac cacataacgg
     6421 gaagtaatgt gaaatattta ctcattttct tactggtatt ggcgattttt gttatttcgg
     6481 tgacgctggg cgcgcagaat gatcaacagg tgacgtttaa ctacctgctg gcgcaagggg
     6541 agtatcgtat ctccacgttg cttgctgtgc tgttcgccgt cggttttgcg attggctggc
     6601 tgatttgcgg cctgttctgg ctgcgggtcc gcgtttccct tgcccgcgct gaacgtaaaa
     6661 ttaaacgact ggaaaacaag ctctcgccag caaccgacgt tgcggtccct gccgattcgt
     6721 cggttgtaaa ggaataatca tttatgttgg agttgttatt tctgctgttg cctgtagccg
     6781 ctgcctatgg gtggtatatg ggtcgcagaa gtgcgcaaca aacaaaacag gatgaagcta
     6841 accgcctgtc gcgcgattat gtcgcagggg ttaacttcct gctgagtaac caacaagata
     6901 aagcggtgga tctgttcctc gatatgctta aagaggatac cggcaccgtt gaggctcatc
     6961 tcactctcgg taatttgttt cgctctcgcg gcgaagtcga tcgcgccatt cgtattcatc
     7021 aaacgctcat ggaaagcgct tcattgacct atgaacagcg tttactggct gttcagcaac
     7081 tggggcgcga ctatatggcc gccggtttat atgaccgcgc ggaagatatg tttaaccaac
     7141 ttaccgacga aacggaattt cgcgtaggcg cgttacagca gctcttgcaa atctatcagc
     7201 taaccagcga ctggcaaaag gcgatcgaag tagcagaacg gctggtgaaa ctgggcaaag
     7261 ataaacagcg tatcgaaatc gcccactttt actgtgagtt agcgttacag cagatgggca
     7321 acgacgacat ggatcgcgcg atggcgttgc tgaaaaaagg tgccgccgca gataaaaata
     7381 gcgcccgggt gtctatcatg atggggcgcg tttatatggc gagaggggat tacgccaaag
     7441 cggtcgaaag cctgcaacgt gtgatcgttc aggataaaga gctggtcagc gaaacgctgg
     7501 agatgttgca aacctgttat caacagctcg gtaaaaatgc cgagtgggcg gagtttttac
     7561 gtcgcgccgt tgaggagaat accggtgctg gcgctgagtt aatgcttgcc gatattctgg
     7621 aagcgcgtga aggtagtgac gcagctcaag tctatatcac gcgtcagcta cagcgacatc
     7681 ctaccatgcg ggtgttccat aagctgatgg attaccatct caatgaggcg gaagaagggc
     7741 gagcgaaaga aagcctgatg gtactgcgtg atatggttgg cgagcaggtg cgcagtaaac
     7801 cgcggtatcg ttgtcagaaa tgcggtttta ccgcctatac cttgtactgg cactgtccgt
     7861 cctgccgggc atggtcgacc attaaaccta ttcgcggact tgatgggcag tagtatataa
     7921 aaaaaacctc actttagtta caacatactt aatgacataa gacaagaaac gacgctggca
     7981 tcggcggcca gggcttatca ggttgtcaat cgaacctgtt aatttccctg cgccgcaggt
     8041 agaatgcacg ccgtttatcc aatttgcgcc acttccggtg cccatcatca agaaggtctg
     8101 gtcatgacgt ttactgcttc atcttcttcc tgcgctatta ctgaatcgcc tgtcgttgtg
     8161 gcgttggatt accatgaacg cgataaagcc ctggcgtttg tcgataaaat cgatcctcgc
     8221 gattgtcgct taaaagtggg caaagagatg ttcacgctgt ttggtccaca actcgttcgg
     8281 gatctccagc aacgtgggtt tgatgtcttt cttgatctaa aatttcatga tattcccaac
     8341 accacggccc gggcagtcgc cgcagcggca gacctgggcg tttggatggt aaacgttcac
     8401 gcgtctggtg gggcgagaat gatggccgca gcgcgcgacg cgctggcgcc attcagtaaa
     8461 gatgcgccgt tgctcattgc cgtgaccgtg ttgaccagta tgggaaccag cgatctacac
     8521 gatctgggcg tgacgttgtc accggcggaa catgcggagc ggctggcgcg cctgacgcag
     8581 caatgcgggc tggatggcgt ggtctgttcc gctcaggaag ctgtcagatt taaacaggcc
     8641 tttggcgctg catttaagct ggtgacgccg ggcattcggc ccgcaggcag cgaggcaggc
     8701 gaccagcgac gcattatgac gcccgaacag gcattatccg ctggcgtcga ctatatggtg
     8761 attggccgcc cggttacgca atcggtagat ccggcgcaaa cgctgaagga tattaacgcg
     8821 tcactgaaac gggaggcata atgagcgatt ccaatagtcg tctggtttat tcaacacaga
     8881 cggggcgcat tgaagaacct aaaacggcgc cggttcgtcc caaaggggat ggtatcgttc
     8941 gcattcagcg tcaaaccagt ggccgtaagg gtaaaggcgt atgtttgatt accggtatcg
     9001 agatgaatga tgcggaatta accaaactgg cggctgaact gaagaaaaaa tgcggctgtg
     9061 gcggggcagt aaaagaaggg attattgaaa ttcagggtga taaacgcgac ttgataaaat
     9121 cattgctgga agctaaagga atgaaagtaa aattagctgg cggctaatga aaacgccacg
     9181 gttgtaaatt gccgtggcgt aaaagtcaac tttgtctatt tttgtaatcc agacctgaaa
     9241 agaataaacg tattattttg agccgttcaa tatttaaacg tctggattat tttccaacct
     9301 ggtgaccaat cacgccgccg accgccgcgc cgcccagggt gcctaatgta ctgccgtccg
     9361 ttaacactgc gccgcctaac gcccccgcac ctgcgccaat agccgtgttg cgatcgcgct
     9421 tggaccagtt tgagcaggcg ctcagagaca ttgctacggt gattgccagc acagcagcgg
     9481 ccattttttt gctcatcata aacataatac tctctcctga attaacgatt cacggaatta
     9541 agctcactat aactatagtt aaaataaaac atgttaagag attttccgta aaacctgatt
     9601 gcgcaggggt atatcacgca ggtgatagtc acttcctgtt atttcgctaa tattaatttt
     9661 acgacgttac gctcgttaca acaggtaaat agtcttaatt gggatgtcag aaaagtctta
     9721 gagagaggat gatttgccat agagggcaaa ccatcgggaa atattttaaa cggatgagcc
     9781 aataacattg actagcagcc ctgcatgctc taactgcatt tgatcgctgg cggaaatttt
     9841 ggaatccgta atgacacgat ggaagcgaga gagcgggccc aggggatagg gatgcacaca
     9901 gccaaatttg gagctgtcgg tgaggacaat cgcttctgag cctttttcca gaacagcgtt
     9961 aaccacatcc gatcgcatca tatcgcgtcc ggtaaagccg gtatcagcct gccagccatc
    10021 aataccgata aatgctttgc tgaaatgcac ttgatggata aactgtcgcg tcaacggccc
    10081 taccatgctt tcactttttt tctgatagat tccaccgagg agaatgactt cgcaaggggt
    10141 ttctttgagc agatgcgcga tataactgct cacggtgatg atcgtgacat ctttttgttc
    10201 cgccagcgtc cgggccaata gcgcattgct actgccattt tcaataaaaa cggattcccc
    10261 aggactgacc agcgaggcgg cgaactccgc cagtcggcgt tttagcgtgt agttcgtcat
    10321 catgcgagtc tctacgtcat cgctctcaag cgaaacggcg aaaccgtgcg cacggcgtaa
    10381 atagctctgt ttttccaggg tattcagatc ctgacgaatc gtgacttcag atacgccggt
    10441 aattttcgcc agttcagcaa cgctcatctg gcctttatca accaccattt gcaaaattga
    10501 ttgttgtcgg gagttcatag tattaatttt attcgttaag aggagtcaac agacagtcag
    10561 agagccggga agggctaacg gccatcccgg acaaataatc gctatcagat ttcccagggc
    10621 gacccgggag cctgggatgg cgagataccg tctttaacct gatctaacag ctctgctctc
    10681 aatatttcaa ggttattgat ggccgagtgg taatcgccag caacaaggat atccagcacg
    10741 gtatcaatgc gtgcggcaat tcgttgtgct tcgatatcag acatgtttgt catccttaat
    10801 gtcagaaaag gtttcaattc atgatgcaga aattaatctg aaaagagaag ggaaaaatag
    10861 ggctatgcct gtctgcacag gctgttctcc ctattatcgc cgccattaac gcattttttt
    10921 cgtctgataa cgtttgtacc agcgttcaaa agaaacggcg ggcataggtt tggcgaataa
    10981 aaagccctgt cgttcattga cgccgttttt tgtcaggaag gcatcttctt tagcattttc
    11041 cacgccttcg gcaatcactt gtaaatttag cgcctgagcc accgcgacaa tcgcccgaac
    11101 cagagattgc gacagcggtt gcttatggat atctctgacg aaagcctgat ccagtttaac
    11161 ggcatcaata gggaaccggg cgagttgaga aagcgaagaa taccctgtgc caaaatcatc
    11221 cagatgaatc tgggcgccga gctgactaaa ttgctggata accgatagcg ccagcgtgtc
    11281 gttttcgatc aggcagcttt ccgttagctc gacatcgatt gggcaatact caaaattcag
    11341 atcgtacaaa gcctgtttaa gcgcagtaaa aagcgtctgg tcggccagtt gtcgcgccga
    11401 aaagttaacg gctacgcgca agttaatccc cttatcgcgc catttcgcaa tctggcgaac
    11461 tacatccaga atcacccagc ggcccagcgg gacgatgagt cctgactctt cggcgtatga
    11521 gatgaactcc agcggcggaa ttaatccgcg ttccggcgat tgccagcgta ccagcgcttc
    11581 caggctacgt acttcgccgc gccaggtaat tttgggctga tagtgaataa gtaactggtc
    11641 gttttccagc gcttttcgca ggtttgtatc cagccagtga tagtcaaata cgcgctgatt
    11701 catttccggc gaaaaaacgc agaactgacc gcggccgcct tctttggcgt tatacattgc
    11761 ggtgtcggca gtgcgaatga gactttcgct gtcctgtccg tgccgggggg ccaacgaaat
    11821 gccaatggcg catcccgtgt aaacttcaat gagtccaatg cgaaacggtt gccgcagccg
    11881 ggtaaggatt cgtgaggcta ctgcttccag cgcggcctga gacgtatggg caacgaggac
    11941 aatgaattca tctcccccca gtctggccag caattgatct tcctccagac aactcaacag
    12001 cgccagtgaa acggcctgta agagctgatc gccaaacata tgcccatagg cgtcattaat
    12061 tttcttgaag ttatccagat cgagataaac gatacccacc tgcgactcgc cagccgaggc
    12121 aatagcatga ttaataaatt catgaatagc attgcgattg ggcaggccgg tgacggtgtc
    12181 tgtattcgcc agtatgcgta aacgctcctg agcccgcctt tcttcggtga tatccgtgcc
    12241 tgcgcagatc agaaagattt cgttttttcc gctaccgtta tggacgaatt tattacgaaa
    12301 taagaacaga cgttggcctt tacgagtctt tatccagcgt tcgatttcat aggcattgcc
    12361 attgcgaaaa aaattctcaa tgtagtgtcg ggaggcaacc gcctcccggc gactcataaa
    12421 taatttaaat acgctttgac caattacatc tcgctctttt aagcccgtgt actcttcgca
    12481 taaccgatta aatcgacaga tttttccccg actatccagt atcgcaatga ctgagttggc
    12541 ttctgatacg atttgctcgg caaaagagag ttcctgcgcc tgcgttggcg cgacggcagg
    12601 cgtatcaggc caggttgcca ggctgccagc ccattcacgg ttattaatct tacggcctac
    12661 caggtgcaca gcggtaacct gtttttctat caacaacgtt atcagcagac tggacgtaat
    12721 cgccgttatt tcccggatac gcccggcttg ctccggcgat agctcaaccg ttttttctgc
    12781 atccgtttca cctgtcgggg agagatacag cacgttgcgg tcatcagcca gacgccagtg
    12841 agagtgaagg ggatttagcg ccgtttgttc ctgaatctgt ttcatcatgc gtaccatccc
    12901 atttaagcgc caggtgcccg aaaagaaagg ttagccatgt tataaataag ggtaattat
//
LOCUS       DAJVKX010000128        12521 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.128, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000128 DAJVKX010000000
VERSION     DAJVKX010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12521
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.128"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            261..752
                     /gene="napF"
                     /locus_tag="OPY25_003618"
     CDS             261..752
                     /gene="napF"
                     /locus_tag="OPY25_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HCS0929124.1"
                     /translation="MVDLSRRSMLTGSWRNASNGILPPWARETTYFLAHCLRCDACIQ
                     ACEADILQRGTGGYPSVNFKRGECSFCYACAQACPESLFLPRRTRAWDLIFTLTENCL
                     ARQSVECHRCLDSCEPMAITFRPTLSGIYQPQLDSQACNGCGACVAICPVSAIKAENH
                     HAH"
     gene            742..1005
                     /gene="napD"
                     /locus_tag="OPY25_003619"
     CDS             742..1005
                     /gene="napD"
                     /locus_tag="OPY25_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HCS0929125.1"
                     /translation="MRTNWQVCSLVVQAKSQNIAAIGTQLNTLPGCEVALSDVESGQL
                     IVVAEADQSETLMQTIESVRNVEGVLAVSLVYHQQDEQGEETP"
     gene            1002..3488
                     /gene="napA"
                     /locus_tag="OPY25_003620"
     CDS             1002..3488
                     /gene="napA"
                     /locus_tag="OPY25_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase catalytic subunit NapA"
                     /protein_id="HCS0929126.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPML
                     RMKDGSYHKDGEFTPVSWEQAFDVMEEKFKTALKEKGPEAIGMFGSGQWTIWEGYAAA
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAE
                     MHPILWSRITNRRLSDPNVKVAVLSTFQHRSFELADNGIVFTPQSDLVILNYIANYII
                     QNNAVNQDFFTKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFDEYKAFVA
                     EYTLDKTAEMTGVPKDQLEQLAQLYADPNKRVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRDICEKHWQIPA
                     GTIPAKVGLHAVAQDRALKDGKLNVYWVMCNNNMQAGPNINEDRMPGWRDPRNFIIVS
                     DPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQIKAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEALLAQKPELRGKTLYDVLFATPAVSKFPLSELKEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHNARGLRWPVVEGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAESPDNEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVVFIHPLDAKARDLRRGDKVKVSSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNNLTLDATDPLSKETDFKKCAVKLAKV"
     gene            3495..4190
                     /gene="napG"
                     /locus_tag="OPY25_003621"
     CDS             3495..4190
                     /gene="napG"
                     /locus_tag="OPY25_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HCS0929127.1"
                     /translation="MSRTAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARATGV
                     RLRPPGALNENVFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALNKDIASIDDSRMGLAVLLDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELDRNMRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGKDGKS"
     gene            4177..5046
                     /gene="napH"
                     /locus_tag="OPY25_003622"
     CDS             4177..5046
                     /gene="napH"
                     /locus_tag="OPY25_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HCS0929128.1"
                     /translation="MANRKRDAGREARAKKGWWRSHRWLVLRRISQFMVLGMFLSGPW
                     LGFWVLHGNYSSSLLFDTLPLTDPLITLESLASGHLPATVALTGAVIIAVLYALAGKR
                     LFCSWVCPLNPVTDLANWMRRKFDLNQSATIPRHIRYVLLVVVLIGSALTGTLLWEWI
                     NPVSLLGRSLIMGFSSGALLIIALFLFDLLVVEHGWCGHICPMGALYGVLGSKGVVTV
                     TAKKREKCNRCMDCFHVCPEPHVLRAPVLDEQSPAQVTHRDCMTCGRCVDVCSEDVFT
                     ITIHNIIRDASRR"
     gene            5162..5611
                     /gene="napB"
                     /locus_tag="OPY25_003623"
     CDS             5162..5611
                     /gene="napB"
                     /locus_tag="OPY25_003623"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HCS0929129.1"
                     /translation="MKSHDLMKALCQWMATLALVVSGAVWAANGVDLSQSPEVSGTQE
                     GAIRMPKEQERMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVSGNVAPRRYFCLQCHVPQSDTAPIIDNTFTPSQGYGK"
     gene            5621..6223
                     /gene="napC"
                     /locus_tag="OPY25_003624"
     CDS             5621..6223
                     /gene="napC"
                     /locus_tag="OPY25_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HCS0929130.1"
                     /translation="MENSNRKLGWIKRVWRWWRSPSRLALGTLLLIGFIGGVIFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYEEYMETVHYNNRSGVRATCPDCHVPHEWGPKMIR
                     KIKASKELYAKVFGLIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFDFMDLTA
                     QKGVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMRDVKPGF"
     gene            6244..6861
                     /gene="ccmA"
                     /locus_tag="OPY25_003625"
     CDS             6244..6861
                     /gene="ccmA"
                     /locus_tag="OPY25_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HCS0929131.1"
                     /translation="MLEARDLYCERDERTLFRGLSFTVEAGEWVQVTGGNGAGKTTLL
                     RLLTGLARPDGGEVYWQGEPLRRVRDSFHRSLLWIGHQPGIKTRLTARENLHFFHPGD
                     GARLPEALAQAGLAGFEDVPVAQLSAGQQRRVALARLWLTRAALWVLDEPFTAIDVNG
                     VARLTRRMAAHTAQGGMVILTTHQPLPGAADTVRRLALTGGGAGL"
     gene            6858..7517
                     /gene="ccmB"
                     /locus_tag="OPY25_003626"
     CDS             6858..7517
                     /gene="ccmB"
                     /locus_tag="OPY25_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HCS0929132.1"
                     /translation="MMWRVFCLELRVAFRHGADIAGPLWFFLMVITLFPLSVGPQPQL
                     LARIAPGIIQVAALLASLLALERLFRDDLQDGSLEQLMLLPVPLPAVVLAKVLAHWAV
                     TGLPLMMLSPLVALLLGMDVYGWKIMALTLLLGTPALGFLAAPGVGLTAGLRRGGVLL
                     GILVLPLSVPVLIFATAAMDAASMHLPVDGYLAVLGALLAGSATLSPFATAAALRIST
                     Q"
     gene            7569..8306
                     /locus_tag="OPY25_003627"
     CDS             7569..8306
                     /locus_tag="OPY25_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease"
                     /protein_id="HCS0929133.1"
                     /translation="MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFA
                     PADYQQGESYRIMYLHVPAAIWSMGIYAAMAVAAFTGLVWQMKMASLAVAAMAPVGAV
                     YTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
                     ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQLSIDPAMRSPLRWAIAGFLLLFMTLAL
                     MRMRNLILLMEKRRPWVSELILKRGHR"
     gene            8303..8515
                     /gene="ccmD"
                     /locus_tag="OPY25_003628"
     CDS             8303..8515
                     /gene="ccmD"
                     /locus_tag="OPY25_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HCS0929134.1"
                     /translation="MSPAFSSWSDFFAMGGYAFFVWLAVAMTVAPLALLALHTVLQRR
                     AILRGVAQQRAREARMRAAQAQQEAA"
     gene            8512..8991
                     /gene="ccmE"
                     /locus_tag="OPY25_003629"
     CDS             8512..8991
                     /gene="ccmE"
                     /locus_tag="OPY25_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HCS0929135.1"
                     /translation="MNLRRKNRLWVVCAVLAGLALTTALVLYALRANIDLFYTPGEIL
                     YGKRETQQLPAVGQRLRVGGMVMPGSVRRDPDSLKVNFSLYDAEGSVTVSYEGILPDL
                     FREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS"
     gene            8988..10919
                     /locus_tag="OPY25_003630"
     CDS             8988..10919
                     /locus_tag="OPY25_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HCS0929136.1"
                     /translation="MMPEYGHALLCLALGVALLLSVYPLWGVARGDARMMASAGVFAW
                     LLFICVAGAFFVLVHAFVVNDFTVAYVAGNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTLAVAVFSRQVPADIVARVLAVMGMVCAGFLAFILFTSGPFARTLPAFPVEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIAALLSGRLDSAFTRFARPWTLAAWVF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLAGTALLHSLAVTEQRAGFKAWT
                     LLLSICAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVTGGSLLLFAVRG
                     HRVRSRVNNALWSRESLLLGNNVLLMAAMLVVLLGTLLPLVHKQLGLGSISVGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRNIRKLLLTALVSTLVLSVLLPWLLEDRIIA
                     MTAVGMAMACWIAVLAVAEAVQRVSRGTKTSLSYWGMVAAHLGLAVTITGIAFSQNYS
                     VERDVRMRAGDSVTIHDYRFTFREVRDITGPNYRGGVALIGVTRHGEPEAVLHAEKRL
                     YNTSRMVMTEAAIDGGLTRDLYAALGEELDNGAWAVRLYYKPFVRWIWAGGLLMALGG
                     LLCLADPRYRRRKPLPEAG"
     gene            10916..11473
                     /gene="dsbE"
                     /locus_tag="OPY25_003631"
     CDS             10916..11473
                     /gene="dsbE"
                     /locus_tag="OPY25_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HCS0929137.1"
                     /translation="MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKP
                     VPAFRLESLETPGQYYQAEVLTQGKPVLLNVWATWCPTCRAEHQYLNRLAAQGIRVVG
                     LNYKDDRAKAVAWLKELGNPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHA
                     GDLNARVWESELKPLWDRYSREAAQ"
     gene            11470..12513
                     /locus_tag="OPY25_003632"
     CDS             11470..12513
                     /locus_tag="OPY25_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein CcmH"
                     /protein_id="HCS0929138.1"
                     /translation="MRLLPGMVMLMLALVISGSARATTDVMPFKDEAQEQQFRQLTEQ
                     LRCPKCQNNSIADSNAMIATDMRRRVYDLMQEGKSRQEIIDYMVARYGNFVTYDPPLT
                     PLTVLLWVLPLAAIVAGGWIIVARTRRRVRLRREPLPADTPVCGARAGWGVYVPGAVI
                     ALAVGAGSYALTGSYPQVRAWQQATAQTPGLLARALDPQAQPLNEEEMARLALGLRTR
                     LQNDAGNVEGWLMLGRTGMVLGNAGTATGAYANAYRLDPENRDAALGYAEALTRSSDP
                     EDNRRGGELLRQLVSRDHTDIRVLSLYAFSAFEQQRFGEAVAAWEMMLKLLPAGDARR
                     AVIERSIRLAQEK"
BASE COUNT         2297 a         3509 c         4209 g         2506 t
ORIGIN      
        1 taatgtaaat gaaattatca gctattagtg atttccgtta tataaatatc tatataactc
       61 attgaaatgt gagaaaaagc acgtttacgg gtctttaccc ggcactcttt tgatccggca
      121 acagcattta cctctatcgg ggtatgcatc tcttacacat cctgaaatat cttatttaca
      181 aaaataacta ctcataaatt gtacggtttt tattggcatt cactccctat ggaagcgtgt
      241 cgttatggaa gggcgatatc atggtcgatt tatcccgtcg aagcatgttg accggcagtt
      301 ggcgcaacgc cagcaatggg attcttccgc cgtgggccag agaaacgacc tattttctcg
      361 cacattgtct gcgttgcgac gcctgcatcc aggcgtgtga ggccgacatc ctgcagcgag
      421 ggacgggggg atatccgagc gtaaatttca aacggggcga gtgcagcttt tgttatgcct
      481 gtgcgcaggc ctgtcccgaa tctctctttc ttccgcgccg caccagggcc tgggatctga
      541 tttttacact cacggaaaac tgcctcgcca ggcagtcggt tgaatgccat cgttgcctgg
      601 acagttgtga acctatggcc attacctttc gtcccacgtt atccggtatt taccagccgc
      661 agcttgactc gcaggcctgt aacggatgcg gggcgtgtgt ggctatctgt cccgtgtcag
      721 ccatcaaagc ggagaaccac catgcgcact aactggcagg tctgtagcct ggtcgtgcag
      781 gccaaaagtc agaacatcgc cgccattggc acacagttga acacgttgcc gggttgcgaa
      841 gtcgcgttaa gcgacgttga aagcgggcaa ctgatcgtgg tggcggaagc agaccagagt
      901 gaaacgctga tgcaaacaat tgagtcagta cgcaatgtcg agggcgtgct ggcggtgtcg
      961 ctggtttatc accagcagga tgagcaaggt gaggaaacac catgaaactc agtcgtcgta
     1021 gctttatgaa agctaacgcc gttgcggccg ctgcggcggc tgccggtctg agcgtgccgg
     1081 gcgtcgcccg cgccgttgtc gggcagcagg aagctatcaa atgggataaa gcgccgtgcc
     1141 gtttttgcgg aacgggttgc ggtgtgttgg tgggaacgca gcagggccgt gtggtcgcct
     1201 gccagggcga ccccgacgcg ccggtcaacc gtggtctgaa ctgcattaaa ggctacttcc
     1261 tgcccaaaat catgtacggt aaagatcgtc tgacgcagcc gatgctgcgc atgaaagacg
     1321 gcagctatca caaagacggc gagtttacgc cggtgagctg ggaacaggcc ttcgatgtga
     1381 tggaagagaa gtttaaaacc gccctgaaag agaaaggacc agaagcgatc ggcatgtttg
     1441 gatcgggtca atggaccatc tgggaaggct atgccgccgc gaaactgttc aaggctggtt
     1501 tccgctctaa caacatcgac ccgaacgcgc gtcactgcat ggcctcggcg gtggtgggct
     1561 ttatgcgcac ctttggcatg gatgaaccga tgggctgcta cgacgatatt gagcaggccg
     1621 atgcgtttgt gctgtggggg tccaacatgg cggagatgca cccgatttta tggtcgcgca
     1681 tcactaaccg ccgtttgtcc gacccgaatg tgaaagttgc tgtcctctcc accttccagc
     1741 accgtagctt tgagctggcg gacaacggta ttgtctttac cccgcaaagc gatctggtga
     1801 tccttaacta tatcgcgaat tacattattc agaacaacgc ggtaaatcag gatttcttca
     1861 caaagcatgt gaatctgcgt aaaggggcga cggatatcgg ctacggctta cgcccgacgc
     1921 acccgctgga aaaagcggcg aagaatccgg gctccgacgc ttccgagccg atgagcttcg
     1981 acgagtataa agccttcgtg gcggaatata cgttggacaa gactgctgaa atgaccggcg
     2041 tgccgaaaga tcaactggaa cagttggcac agctctacgc cgatccgaat aagcgcgtga
     2101 tctcttactg gacgatgggt tttaaccagc atacccgcgg cgtgtgggcg aataacctgg
     2161 tttacaacct ccatctgctg accggaaaaa tctcccagcc tggctgcggt cctttctcgc
     2221 tgaccggcca gccttccgcc tgcggtacgg cgcgtgaagt gggaaccttc tcacaccgtc
     2281 tgcccgcaga catggtcgtg acgaacgaaa aacaccgtga tatctgcgaa aaacactggc
     2341 agatccccgc tggcactatc ccggcaaaag tgggtttaca tgcggtggcg caggatcgcg
     2401 cgttgaaaga cggcaagctg aacgtctact gggtaatgtg taataacaat atgcaggccg
     2461 ggccgaacat caatgaagat cggatgccgg gctggcgcga tccgcgtaac tttatcattg
     2521 tctccgatcc ttacccgacg gtgagcgcgc tgtctgctga tctgatcctg ccgaccgcca
     2581 tgtgggttga gaaagaaggc gcttacggca acgccgaacg ccgcacgcag ttctggcgtc
     2641 agcaaattaa agcgccgggc gaagccaaat ccgacctctg gcaactggtg cagttctccc
     2701 gtcgttttaa aaccgaggag gtctggccgg aggcgttgtt ggcccagaag ccggagctgc
     2761 gcggcaaaac gctgtatgac gttctattcg ccacgcctgc ggtcagcaaa ttcccgctga
     2821 gcgagctgaa agaagatcag ttaaacgatg agtctcgtga gctgggcttc tatctgcaaa
     2881 aagggctatt tgaagaatac gcctggtttg gacgtggcca cggtcacgat ctggcgccgt
     2941 tcgacgatta ccacaacgcg cgcggtctgc gctggccggt cgtcgaaggc aaagagacgc
     3001 aatggcgtta cagcgaaggc aacgacccgt atgtaaaagc gggggaaggg tacaaattct
     3061 acggtaaacc ggatggcaaa gcggtgatct tcgcgctgcc atttgaaccc gcggcggagt
     3121 cgccggacaa cgagtacgat ctgtggcttt ccaccggtcg cgtactggaa cactggcata
     3181 ccggcagtat gacgcgccgc gtgcctgaat tgcatcgcgc cttcccggaa gcggtggtct
     3241 ttattcaccc gctggatgcg aaagcgcgcg atctgcgtcg tggggataag gttaaagtgt
     3301 cgtcccgccg cggcgaagtg atttcgattg tcgaaacgcg tggacgtaac cgtccgccgc
     3361 agggactggt gtatatgccg ttcttcgatg ccgctcagct agtgaacaac ctgacgctgg
     3421 atgcgacgga cccgctctct aaagagacgg acttcaagaa gtgcgccgtt aagctggcga
     3481 aggtgtaacg cgttatgtcc cgtacagcga aaccccaaaa tggccgccgc cgctttctgc
     3541 gtgatgttgt gcgcactgcg ggcgggctgg cggcggttgg cgtggcgctg ggcttgcaac
     3601 agcaaaccgc gcgcgcaacg ggcgtgcggc tgcgtccgcc tggcgcgctg aatgaaaatg
     3661 ttttcgccag cgcctgtgtg cgctgcgggc agtgcgttca ggcgtgtcca tacgacacgc
     3721 taaaactggc gacgctggcc tccgggctat cggcaggtac gccctatttc gtcgctcgcg
     3781 acatcccctg cgaaatgtgt gaagacattc cgtgcgccaa agtctgcccc agcggggcgc
     3841 tgaataaaga tatcgcctcc attgatgact cgcgcatggg gctggcggtg ctgctggatc
     3901 aggaaaactg cctcaacttt caggggctgc gctgcgacgt ttgctaccgc gaatgcccga
     3961 aaatcgatga ggccatcacg ctggagctgg atcgcaacat gcgcactggc aaacatgcgc
     4021 gctttctgcc caccgtacac agcgacgcct gtaccggctg cggcaaatgc gaaaaagtct
     4081 gcgtactgga gcaaccagcg ataaaagtgt tgccgttgtc attggcgaaa ggggagttag
     4141 gacaccatta ccgcttcggc tggctggagg ggaaagatgg caaatcgtaa acgcgacgcc
     4201 gggcgagaag cgcgggcgaa aaaaggctgg tggcgtagcc accgttggct ggtgttacgc
     4261 cgtatcagcc agtttatggt gctggggatg tttctcagcg gcccgtggct gggcttttgg
     4321 gttttgcatg gcaactacag cagtagtttg ctgttcgata ccctcccgtt gaccgatccg
     4381 ctgattaccc tggaaagtct cgccagtgga catcttcccg ctaccgtggc gctgacggga
     4441 gcagtgatta tcgctgtgct gtatgcgctg gcgggaaagc gattattttg cagttgggtt
     4501 tgcccgctaa accccgttac cgatttggct aactggatgc gcaggaaatt tgacctgaac
     4561 cagtcggcga cgattccacg ccatatacgg tatgtccttc tggtggtggt gttaatcggt
     4621 tcggcgttga ccggcacgct gctgtgggaa tggattaatc ccgtgtcgct gttaggtcgt
     4681 agtctgatta tgggatttag tagcggcgcg ttgctgatta ttgctttgtt tttatttgat
     4741 ttattagtcg ttgagcacgg ttggtgcggt catatttgcc cgatgggcgc gctgtatggc
     4801 gtgctgggca gtaaaggcgt agtgaccgtg acggccaaaa aacgtgagaa atgtaatcgc
     4861 tgtatggatt gttttcatgt ttgcccggaa ccgcatgtgc tacgtgcgcc ggtgctggat
     4921 gagcaaagcc cggcgcaggt cactcaccgc gactgcatga cctgcggtcg ctgcgtggat
     4981 gtctgttctg aggatgtttt tacaataacg atacacaaca tcattcggga tgcatcgcgg
     5041 cggtaagcga ggaaatcccc gggagcatag ataacgatgt gactgggatt ttcgagcgca
     5101 gccaacaaag aggcagctcg aaggatgaag tgtaaatgcg atggagttcg ggagcgaaac
     5161 aatgaaaagc catgacctga tgaaagcgct gtgtcaatgg atggccacgc ttgccctggt
     5221 ggtaagtggt gcggtttggg cggcaaacgg agtggatctg agccagtcgc cggaagtatc
     5281 cgggacgcag gaaggggcga ttcgtatgcc gaaagagcag gaacgtatgc cgctaaatta
     5341 cgtcaaccag ccgccgatga tcccgcacag cgtcgagggc taccaggtga cgaccaatac
     5401 caaccgctgt ctgcaatgcc acggcgtgga aagttatcgt acgacgggcg cgccgcgtat
     5461 cagtccgacg cactttatgg acagcgacgg taaagtgtcg ggcaacgtcg cgccgcgtcg
     5521 ttatttctgc ctgcagtgcc acgtaccgca gtctgatacc gcgccgatta tcgacaatac
     5581 ctttaccccc tcgcaaggtt acgggaaata agaggtcatt atggaaaatt ctaaccgtaa
     5641 acttggctgg ataaagcgcg tctggcgatg gtggcgcagc cccagccgcc tggcgctggg
     5701 gacgctgctg ttaatcggtt ttatcggcgg cgtcatcttc tggggcggct tcaataccgg
     5761 aatggaaaag gctaataccg aagagttttg tattagctgc catgaaatgc gcaacacggt
     5821 gtatgaggag tatatggaaa ccgtccacta caacaaccgt agtggcgttc gcgccacctg
     5881 tcctgactgc catgtgccgc atgagtgggg gccgaagatg atccgtaaga tcaaagccag
     5941 taaagaactg tacgcgaagg tatttgggct gatagataca ccgcagaaat ttgaagctca
     6001 tcgcctgaca atggcacaaa atgagtggcg gcgcatgaaa gacaacaact cgcaggaatg
     6061 ccgtaactgc cacaatttcg actttatgga tctgaccgcg caaaaaggcg tcgcggcgaa
     6121 aatgcacgat caggcggtaa aagatggaca gacctgtatc gattgccaca aagggatcgc
     6181 gcataaactg ccggatatgc gtgatgttaa accaggtttc tgacaggacg ttgatgagtg
     6241 ggaatgcttg aagccagaga tctgtactgc gagcgggacg agaggacgct gtttcgcggg
     6301 ctgtcgttca ccgtggaggc cggggagtgg gtgcaggtca ccggcggcaa cggcgccgga
     6361 aaaaccaccc tgctgcgcct gctgaccggg ctggcgcgcc cggacggcgg ggaggtgtac
     6421 tggcagggcg agcccctgcg ccgcgtgcgc gacagcttcc atcgcagcct gctgtggata
     6481 gggcaccagc cggggataaa aacccgcctg acggcgcggg agaacctgca ctttttccac
     6541 cccggtgacg gcgcgcgtct cccggaggcg ctggcgcagg ccgggctggc gggatttgag
     6601 gacgtgccgg tcgctcagct ctcggccggg cagcagcgcc gggtggcgct ggcccgcctg
     6661 tggctgaccc gcgccgcgct gtgggtgctc gacgagccgt tcaccgccat tgacgttaac
     6721 ggcgtggcgc gcctcacccg gcggatggcg gcgcacacgg cgcagggcgg gatggtcatc
     6781 ctcaccaccc accagccgct gccgggggcc gcggacaccg tccgccgcct ggcgctgacc
     6841 ggcggggggg ccgggctgtg atgtggcgtg tcttctgtct cgagctgcgc gtggcgttcc
     6901 gccacggcgc ggacatcgcc ggcccgctgt ggttcttcct gatggtcatc accctgtttc
     6961 cgttaagcgt cgggccgcag ccgcagctgc tggcgcgtat cgcgccgggc atcatccagg
     7021 tggcggcgct gctggcctcg ctgctggcgc tggagcggct gtttcgcgac gacctgcagg
     7081 acggcagcct ggagcagctg atgctgctgc cggtgccgct gccggcggtg gtgctggcga
     7141 aggtgctggc ccactgggcg gtgaccggcc tgccgctgat gatgctctcc ccgctggtgg
     7201 cgctgctgct ggggatggac gtgtacggct ggaaaatcat ggcgctgacg ctgctgctcg
     7261 gcacgccggc gctggggttt ctcgccgcgc cgggcgtcgg gctgacggcc ggcctgcggc
     7321 gcggcggcgt cctgctgggc attctggtgc tgccgctgag tgtcccggtg ctgattttcg
     7381 ccaccgcggc gatggacgcg gcatcgatgc atttacccgt tgacggctat ctggcggtgc
     7441 tgggggcgct gctggcgggc agcgcgacgt taagcccgtt cgccaccgcg gcggcgctgc
     7501 gcatcagtac gcagtagcgc cccggcacga cggacatttt actggtttca ggaggtcagg
     7561 tgacgactat gtggaaaacc cttcatcagc tggcggcgcc gccccggctg tatcagattt
     7621 gcggcaggct tgtgccgtgg ctggcggcag ccggcatcat tgtgctggcc acgggctggg
     7681 tccggggctt tggtttcgcc ccggcggact accagcaggg ggagagctac cgcattatgt
     7741 acctgcatgt cccggcggcc atctggtcga tgggtatcta tgcggcgatg gcggtggcgg
     7801 cgttcaccgg gctggtctgg cagatgaaaa tggccagcct tgccgtcgcg gcgatggcgc
     7861 cggtgggggc ggtgtacacc ttcatcgcgc tggtcaccgg cgcggcgtgg ggcaaaccga
     7921 tgtggggcac ctggtgggtg tgggacgcgc gcctgacctc ggagctggtg ctgctgtttc
     7981 tctatgccgg ggtcatcgcc ctgtggcacg cctttgacga ccgtaaaatg gccgggcgcg
     8041 cggcgggcat tctggtgctg gtcggcgtgg tgaacctgcc ggttatccac tattccgtcg
     8101 agtggtggaa caccctgcac cagggctcga cgcggatgca gctgagtatc gacccggcga
     8161 tgcgctcgcc gctgcgctgg gccatcgccg gcttcctgct gctctttatg acgctggcgc
     8221 tgatgcggat gcgcaacctg attttactga tggaaaaacg ccgcccgtgg gtgagcgaac
     8281 tgatactgaa aagggggcac cggtgagtcc ggcattttca tcgtggagcg attttttcgc
     8341 catgggcggg tacgcctttt ttgtctggct ggcggtggcg atgaccgtgg cgccgctggc
     8401 gctgctggcg ctgcacacgg tgctgcagcg ccgggccatt ctgcgcggcg tggcgcagca
     8461 gcgggcgcgc gaggcgcgga tgcgtgccgc acaggcgcaa caggaggccg cgtgaacctg
     8521 cgacgtaaaa accggctatg ggtggtctgc gcggtgctgg cgggcctggc gctgaccacc
     8581 gccctggtcc tgtacgcgct gcgcgcgaat atcgacctgt tctatacccc cggcgaaatc
     8641 ctctacggca agcgcgagac gcagcagctg ccggcggtgg gccagcgcct gcgcgtcggc
     8701 gggatggtga tgcccggcag cgtcaggcgc gacccggact cgctgaaggt gaacttcagc
     8761 ctctacgacg ccgaagggtc ggtgacggtg agctatgagg ggatactgcc ggacctgttc
     8821 cgcgaggggc agggggtggt ggtgcagggc accctggaga agggcaacca cgtcctggcg
     8881 cacgaggtgc tggccaagca tgacgagaac tacaccccgc cggaagtgga aaaggcgatg
     8941 caggaaaacc accgccgccc gcaacgcgct gataaggaca cttcatcatg atgcctgaat
     9001 acggccacgc actgctgtgc ctggcgctcg gcgtggcgct gctgctgtcc gtttacccgc
     9061 tgtggggcgt ggcgcgcggc gacgcgcgga tgatggcgtc ggccggggtg ttcgcctggc
     9121 tgctgttcat ctgcgtggcg ggcgcgtttt tcgtgctggt gcacgccttt gtggttaacg
     9181 acttcaccgt ggcctatgtc gccggcaact cgaacacgca gctgccggtg tggtaccggg
     9241 tggccgccac ctggggggcg cacgagggct cgctgctgct gtgggtgctg ctgatgagcg
     9301 gctggaccct ggcggtggcg gtgttcagcc ggcaggtgcc ggcggatatc gtcgcccggg
     9361 tgctggcggt gatggggatg gtctgcgccg gttttctggc gttcatcctg ttcacctccg
     9421 gcccgtttgc ccgcacgctg ccggcctttc cggtggaggg gcgcgacctg aacccgctgc
     9481 tgcaggaccc ggggctgatt ttccacccgc cgctgctgta catgggctat gtcggcttct
     9541 cggtggcctt cgccttcgcc atcgccgcgc tgctgagcgg gcgtctggac agcgcgttca
     9601 cccgttttgc ccgcccgtgg acgctggcgg cgtgggtgtt cctgacgctg ggcatcgtgc
     9661 tcggctcggc gtgggcctac tacgagctgg gctggggcgg ctggtggttc tgggacccgg
     9721 tggagaacgc ctcctttatg ccgtggctgg cgggcaccgc cctgctgcac tcgctggcgg
     9781 tcaccgaaca gcgcgccggc tttaaggcgt ggacgctgct gttgtccatc tgcgccttct
     9841 cgctgtgcct gctgggcacc ttcctggtgc gctccggggt gctggtgtcg gtgcacgcct
     9901 tcgcctccga cccggcgcgc ggaatgttta tcctcgcctt tatggtgctg gtcaccggcg
     9961 gctcgctgct gctgttcgcc gtgcgcgggc acagggtgcg ttcgcgggtg aacaacgcgc
    10021 tgtggtcgcg tgagtcgctg ctgctcggca acaacgtcct gctgatggcc gccatgctgg
    10081 tggtgctgct gggtaccctg ctgccgctgg tgcacaaaca gctggggctg ggcagcattt
    10141 cggtggggga gccgttcttt aacaccatgt tcacctggct gatggtcccc tttgccctgc
    10201 tgctgggggt ggggccactg gtgcgctggg gccgggaccg gccgcgtaac atcaggaaac
    10261 tgctgctcac cgccctggtc tccaccctgg tgctgtcggt acttttgcca tggctgctgg
    10321 aagatagaat catcgccatg acggcggtgg ggatggcgat ggcctgctgg attgcggtgc
    10381 tggcggtggc cgaagccgta cagcgcgtgt cccgcggcac gaaaacctct ctcagctact
    10441 ggggaatggt ggcggcgcac ctcgggctgg cggtgacgat taccggtatc gccttcagcc
    10501 agaattacag cgtggagcgt gacgtgcgga tgcgggcggg cgacagcgtg accattcacg
    10561 actaccgctt caccttccgg gaggtgcggg acatcaccgg gcccaactac cgcggcgggg
    10621 tggccctcat cggggtgacg cgccacggcg agccggaggc ggtgctgcac gcggagaaac
    10681 ggctctacaa caccagccgg atggtgatga ccgaggcggc gattgacggc gggctgaccc
    10741 gcgacctgta cgccgcgctc ggggaggagc tggacaacgg cgcgtgggcc gtgcgcctgt
    10801 actacaaacc gtttgtccgc tggatatggg ccggggggct gctgatggcg ctgggcgggc
    10861 tgctgtgcct ggcggacccg cgctaccgcc gccgtaaacc attgccggag gccggatgaa
    10921 acgcaacgta ctgttattac cgctgctgat ttttctgctg attgccgcgg cgctgctgtg
    10981 gcagctggcg cgcaacgcgc agggggatga cccgacgaat ctcgaatcgg cgctgaccgg
    11041 aaagccggtg ccggcgtttc gcctggaatc gctggagacg ccgggtcagt actatcaggc
    11101 ggaggtgctg acgcagggga aaccggtgct gcttaacgtc tgggccacct ggtgcccgac
    11161 ctgccgcgcc gagcatcagt acctgaaccg gctggccgcg cagggtatcc gggtggtggg
    11221 gctgaactat aaggacgacc gggcgaaggc ggtggcctgg ttaaaggaac tgggcaaccc
    11281 gtatgcgctg agtttatcgg acagcgacgg gatgctgggg ctggacctgg gcgtgtacgg
    11341 cgcgccggaa accttcctca tcgacggcag ggggattatc cgctaccgcc atgcgggcga
    11401 tttgaatgcc cgggtatggg aaagtgaact gaaaccgctg tgggacagat acagccggga
    11461 ggcggcgcaa tgagactgtt accgggcatg gtgatgctga tgctggcgct ggttatctcc
    11521 gggtcagcgc gggcgaccac cgacgtgatg ccgtttaaag atgaagcgca ggagcagcag
    11581 ttccgccagc tcacggagca gctgcgctgc ccgaaatgcc agaacaacag cattgcggac
    11641 tcgaacgcga tgatagccac cgacatgcgc cgcagggtgt atgacctgat gcaggagggg
    11701 aagagccgcc aggaaatcat cgattacatg gtggcgcgct acggcaactt cgtcacctac
    11761 gacccgccgc tgaccccgct gacggtgctg ctgtgggtgc tgccgctggc cgccatcgtg
    11821 gcgggcgggt ggataatcgt cgcccggacg cgccggcggg tgcgcctgcg ccgggagccg
    11881 ctgccggcgg acaccccggt ttgcggcgcg cgcgccgggt ggggcgttta cgtgccgggg
    11941 gccgtcattg cgctggcggt cggcgccggc agctacgccc tgaccggcag ctatccgcag
    12001 gtgagggcct ggcagcaggc aacggcgcag acgcccgggc tgctggcgcg ggcgctggac
    12061 ccgcaggcgc agccgctgaa tgaggaggag atggcgcggc tggcgctggg gctgcgcacc
    12121 cgcctgcaga atgatgccgg caatgttgag ggctggctca tgctggggcg caccggtatg
    12181 gtactgggta atgccggtac cgccaccggg gcgtatgcga acgcttaccg tctggacccg
    12241 gaaaaccgcg atgcggcgct gggctacgcg gaggcgctga cgcgctcgtc cgacccggag
    12301 gataaccgcc gcggcgggga actgctgcgt cagctggtga gccgcgacca cacggatatc
    12361 cgggtgttaa gcctgtatgc gttcagcgcc tttgagcagc agcgctttgg cgaggcggtg
    12421 gcggcctggg agatgatgct gaagctgctg ccggcgggtg acgcccggcg ggcggtgata
    12481 gagcgcagta tccggctggc gcaggagaaa taagaccctg a
//
LOCUS       DAJVKX010000129        12254 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.129, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000129 DAJVKX010000000
VERSION     DAJVKX010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12254
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.129"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            69..428
                     /locus_tag="OPY25_003633"
     CDS             69..428
                     /locus_tag="OPY25_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HCS0929139.1"
                     /translation="MKKILVCFVGLALTACSANSLNYGAEQVRVMTSEPGKECSYLGD
                     ITGSQGNFFTGGWTSNSNLETGARNDLKNKAYKMGDNTVVLLTQRAGQTGSSWHGSGS
                     SKQTNVTLSGNVYRCPR"
     gene            complement(498..1055)
                     /gene="mdsC"
                     /locus_tag="OPY25_003634"
                     /pseudo
     CDS             complement(498..1055)
                     /gene="mdsC"
                     /locus_tag="OPY25_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521068.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdsC"
     gene            1185..1379
                     /gene="golB"
                     /locus_tag="OPY25_003635"
     CDS             1185..1379
                     /gene="golB"
                     /locus_tag="OPY25_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gold resistance metallochaperone GolB"
                     /protein_id="HCS0929140.1"
                     /translation="MQFHIDDMTCGGCASTVKKTILTLDANATVRTDPATRLVDIETS
                     LSAEQIAAALQKAGFPPRER"
     gene            1670..2923
                     /locus_tag="OPY25_003636"
     CDS             1670..2923
                     /locus_tag="OPY25_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929141.1"
                     /translation="MYTPLNWTTTQRHVAFASFTSWMLDAFDFFILVFVLSDLAEWFH
                     ASVSEVSIAIMLTLAVRPIGALLFGRMAEKYGRRPILMLNILFFTVFELLSAWSPTFM
                     AFLIFRVMYGVAMGGIWGVASSLAMETIPDRSRGLMSGIFQAGYPCGYLFASVIFGLF
                     YSMVGWRGMFLIGALPVVLLPYIWFKVPESPVWLAARARKENTALLPVLRKQWKLCLY
                     LVLVMAFFNFFSHGTQDLYPTFLKMQHGFDPHLISIIAIFYNIAAMLGGIFYGTLSER
                     IGRKKAIMIAAFLALPVLPLWAFSSGSFTIGLGAFLMQFMVQGAWGVVPTWLNELVPA
                     NARAVLPGFVYQLGNLLASVNATLQARIAETHGGNYGLAMAIVAGAVAILICVFVAFG
                     RETRGVVISGTDSDALPESAIGHRT"
     gene            3112..5070
                     /locus_tag="OPY25_003637"
     CDS             3112..5070
                     /locus_tag="OPY25_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HCS0929142.1"
                     /translation="MLKDNQKHNESVAPNSAFLSELQRALPEFFIADRYNEQGELIAK
                     GGFDLAKFERALKARNIDELTSGYQIDFIGKDYAKKQAGEKSVTVIVPDVEHNTLAEN
                     KNSHNLFLTGDNLDVLRHLQNNYADTVDMIYIDPPYNTGSDGFVYPDHFEYSDRALQD
                     MFGLNDTELARLKSIQGKSTHSAWLSFMYPRLFLARKLLKDTGFIFISIDDNEYANLK
                     LMMDEIFGEGGFVTNVMWKRKKEISNDSDNVSIQGEYILVYAKTGQGALRLEPLSKEY
                     IQKSYKEPTEQFPEGKWRPVPLTVSKGLSGGGYTYKITTPNGTVHERLWAYPEASYQK
                     LVADNLVYFGKDNGGIPQRVMYAHHSKGQPTTNYWDNVASNKEGKKEILDLFGDNVFD
                     TPKPTALLKKIIKLAIDKDGVVLDFFAGSGTTAHAVMALNEEDGGQRTFILCTIDQAL
                     SNNTIAKKAGYNTIDEISRERITRVAAKIRANNPATNSDLGFKHYRFATPTQQTLDDL
                     DSFDIATGHFINTSGQLAAFTESGFTDMINPFSARGLGVPGGASGEETLLTTWLVADG
                     YKMDIDVQTVDFSGYCARYVDNTRLYLIDERWGTEQTRDLLNHIGTHQLPVQTIVIYG
                     YSFDLESIRELEIGLKQLDQKVNLVKRY"
     gene            5080..8051
                     /locus_tag="OPY25_003638"
                     /pseudo
     CDS             5080..8051
                     /locus_tag="OPY25_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459353.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction-modification system
                     endonuclease"
     gene            8327..8428
                     /locus_tag="OPY25_003639"
     CDS             8327..8428
                     /locus_tag="OPY25_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929143.1"
                     /translation="MLNRYYRFAVEKDDPSEAPESGDKPDSQPQKKS"
     gene            8543..9946
                     /locus_tag="OPY25_003640"
     CDS             8543..9946
                     /locus_tag="OPY25_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HCS0929144.1"
                     /translation="MEFDAFFLARLQFAFTVSFHIIFPAITIGLASYLVVLEGLWLKT
                     RNPVWRSLYQFWLKIFAVNFGMGVVSGLVMAYQFGTNWSGFSQFAGSITGPLLTYEVL
                     TAFFLEAGFLGVMLFGWNKVGPGLHFLSTCMVALGTLMSTFWILASNSWMHTPQGFEI
                     HNGQVVPVDWFAVIFNPSFPYRLLHMSVAAFLSSAMFVGASAAWHLLKGNDTPAIRRM
                     FSMALWMAVVVAPVQALIGDMHGLNTLKHQPVKIAAIEGHWENTPGEPTPLTLVGWPD
                     MEAERTRYALEIPALGSLILTHSLDKQVPALKDYPKEDRPNPTVVFWSFRLMVGMGVL
                     MIFLGLASLWLRYRRRLYHSRPFMHFALWMGPSGLIAILAGWVTTEVGRQPWVVYGLL
                     RTRDAVSAHSTLQMSISLLAFFVVYSLVFGVGYIYMIRLIQKGPQPAETPTAETDGRP
                     ARPISAVGESLEQEKRE"
     gene            9943..10953
                     /gene="cydB"
                     /locus_tag="OPY25_003641"
     CDS             9943..10953
                     /gene="cydB"
                     /locus_tag="OPY25_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HCS0929145.1"
                     /translation="MTIDLPVIWFAIIVFATLMYIVMDGFDLGVGILFPFIRDKHDRD
                     VMVNSVAPVWDGNETWLVLGGAGLFGAFPLAYAVITDALTIPLVVMLLGLIFRGVAFE
                     FRFKATESHRAFWDKSFIVGSILATFAQGVVVSAVVSGFQVEGRTFSGSQLDWLTPFN
                     LFCGVGLVVTYALLGATWLIMKSEDPLHSRMCALSRPLLIVLLLVMGGVSVWTPLTHD
                     DIAERWFTLPNLYYFLPVPVLVLAFSVWLWRSVKKPQSHARPFILTLGLIFLGFSGLG
                     ISIWPNIIPPDISLYAAAAPSQSQSFMLVGALIIIPIILAYTFWSYYVFRGKVRHGEG
                     YH"
     gene            10953..11084
                     /locus_tag="OPY25_003642"
     CDS             10953..11084
                     /locus_tag="OPY25_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2474 domain-containing protein"
                     /protein_id="HCS0929146.1"
                     /translation="MVKVKKWSRRVVWMVAIWCASVLLLAGVGMLFRLLMTSAGFRS"
     gene            11290..>12254
                     /locus_tag="OPY25_003643"
     CDS             11290..>12254
                     /locus_tag="OPY25_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929147.1"
                     /translation="MSPISCHSSAAPAMKKIFSVSDFIAFGERYGIDYRFPALPQYTQ
                     SSPVLHGDIEEIALPGGICITRSDVHVLQPYETTSRHSSPLYMLVVLEGNVALAVNEQ
                     TFLLSAGMAFCSQLSEQQTIRAHHGADSKLRTLSLGMYPDGGWRERLPVSLADEWERS
                     AASARVWQVPEFLLSGLRYAQQPGPHAASRQLMLEGIMLQLLGYALNLCQPATQKRGL
                     PVTGEYQRLELIRRLLEQTPEKAYTLNELARRAAMSPSSLRCKFRHAYGCTVFDYLRD
                     CRLARARRYLMEGYSVQQAAWMSGYQHATNFATAFRRRYGCSPGEL"
BASE COUNT         2789 a         2968 c         3319 g         3178 t
ORIGIN      
        1 tagttccttg acggcgttca gaagcaagaa cgcgttatta tttaatgatt aatagaccag
       61 gtattagtat gaaaaagatc ttagtatgtt tcgtcggctt ggctttaacc gcatgtagcg
      121 ctaattcgct gaattatggc gctgaacagg tacgggtgat gaccagcgag ccaggtaagg
      181 aatgcagcta cttaggagat atcacgggca gccaggggaa tttctttacc ggtggctgga
      241 cttccaacag taacctggaa acgggggccc gtaacgatct gaaaaacaaa gcttataaaa
      301 tgggcgacaa tacggtagtc ctgttaaccc agcgtgcagg ccagacagga agttcatggc
      361 acggttcggg ctcaagcaaa caaacgaatg tcacgttaag cgggaacgtt tatcgttgcc
      421 ctcgttaacc ttattttgca ggcaatatat gcctgtttag cgcgcgcgcc gcactggcga
      481 cgcgcgcgct atttgggcta accttgcttt ttctcgctgt attcccgcca accgccgcct
      541 aatgctttat acaggctaat gatattcaac tgttgcatga gacgtgtgcg taccagacgc
      601 tgttgcgcgc cataaagcat acgatgggta tcaagcagcg taaggtagtc atcgacgcct
      661 tcctgaaaac ggagtccggc cagctcatag gcgatttggc tggcttcaac cgcgcgttgt
      721 tctgattgca cctggtcatt cagcgtacgc tgtcccgcca gaccatccgc cacgtcgcga
      781 aaggcttgct gaataacgtt ttcataccag gcgatttcaa tctgtttttg gacatgcgcc
      841 ctatccaggt cagcgcgtaa tgcgccgccg tgaaagagag gcaaggtgat ttgcggtaga
      901 aaacgccagc ttcccgatcc cggttcaaag agtccgctaa gagacgcgct ggccgttccc
      961 gccgagcctg tcaggctgat ggtcgggaag aaggcggcgc gcgctgcgcc tatccgggcg
     1021 tttgcgccgc gcagcctgta ctcggaggcg cgtaccggag cggtattgcg ccgtcctcgt
     1081 cgccacggac tggcaaagcg tctgtaagtc ctgagattac gcttgacctt ccaacactga
     1141 caaggcccag actggcaaca gttcccacac aaaaggagtt cactatgcag ttccatattg
     1201 atgacatgac ctgcggcggc tgcgccagta cggtaaaaaa gacgattctg actctcgatg
     1261 ctaatgcgac ggtgagaacc gacccggcga cgcgtctggt tgacattgaa acgtcgctat
     1321 ccgcggagca gattgccgcc gccctgcaaa aggccggttt cccgccgcgc gagaggtaat
     1381 cgtcaatggc gatcggtctg gcgacaggcc ggtcgcgata cgctagccac gcttcgcttt
     1441 tctttgcgtg agataatccc cataaaaaat gtgacaaatc atgtgccagt aagctttgtt
     1501 aataatatgt aatgatttgt ctatttttgc taacatttta cctgctatat acaaaaagat
     1561 aacaaataag tagcgcaacg ctaccttgtt acgtcgcttt gacgacggga gcgctccagc
     1621 gtttcgccgc ttcaaagctt gatgttattt ttgatgcagg acactaccta tgtacacccc
     1681 cctgaactgg acgacgacac aacgacatgt ggcgtttgcc agctttacca gttggatgct
     1741 ggatgcgttt gatttcttta tccttgtctt tgtacttagc gatctcgccg aatggtttca
     1801 cgcttccgta tcggaggttt ccattgcgat tatgctgacc ctggcggtac gtcccattgg
     1861 cgcgctgcta tttggccgaa tggcggaaaa gtacggacgt cgaccgatac tgatgctcaa
     1921 tattctgttc tttacggtgt ttgaactgct ttccgcctgg tcgcccacct tcatggcatt
     1981 tctgattttt cgggtcatgt acggcgtggc gatgggcggg atatggggcg tcgcgtcatc
     2041 actggcgatg gaaaccattc ccgatcgttc gcgtggcctg atgtcgggca tttttcaggc
     2101 aggctatccc tgcggctatc tgttcgcctc ggttattttt ggcctcttct acagtatggt
     2161 aggctggcgt ggcatgttcc tgattggcgc cctgcctgtt gtcttgctgc cttatatctg
     2221 gtttaaagtg ccggaatccc ccgtctggct ggcggccaga gcgcgtaaag agaataccgc
     2281 gctgcttcct gttctgcgca aacagtggaa gttgtgtctg tatctggtgc tggtcatggc
     2341 gttctttaac tttttcagtc acggcacgca ggatctctat cctaccttcc tgaagatgca
     2401 gcatggtttt gatccgcatc tgatcagtat cattgcaatt ttttataaca ttgccgccat
     2461 gctcggcggt attttctacg gtacgctatc ggaacgtatt gggcgtaaaa aagcgatcat
     2521 gatcgccgcc tttcttgcgc ttccggtact cccgctatgg gcattttcca gcggatcatt
     2581 cacgattggt ctgggcgcgt tcctgatgca gtttatggtg cagggcgcct ggggtgtcgt
     2641 gccgacctgg ctgaacgagc tggttccggc gaatgcgcgc gccgtgctgc cagggtttgt
     2701 ttaccaactc ggtaatttac tggcgtcggt taatgcgacg ttacaggccc gcatcgcgga
     2761 aacgcatggt ggcaattacg ggttggcaat ggcgatcgtg gctggcgcgg tggctatttt
     2821 aatctgtgta tttgtggcat ttggtcgcga gacccgggga gtcgtcatct ccggtacaga
     2881 tagcgacgcc ctcccggagt cggccatcgg tcatcgcacg taaacactac gctcctggcg
     2941 catactgtcg ccgggagcgc tccttcctcc tgtggttttt acgccctttc aacgaacaac
     3001 aaaggttaat gatggcatct gcctttcgtg accattacaa tcatcgctta cttttttctt
     3061 tataagaaat tgattgttgg accttaaaat tgtcaacgga gcgaagatat catgttgaaa
     3121 gataaccaaa aacacaacga gtctgttgcc ccgaatagcg cctttctgtc tgagttacaa
     3181 cgtgcattac cggaattttt tatcgccgat cgctataacg agcagggcga actgatcgcg
     3241 aaaggcggat ttgatctcgc caaatttgag cgcgcgctga aagcgcgtaa tattgatgag
     3301 ctgactagcg gttatcagat tgattttatt ggcaaagatt acgcaaaaaa acaggcgggt
     3361 gaaaaatccg ttaccgttat cgttcctgac gtggaacaca atactctggc agaaaataaa
     3421 aacagccata atctttttct gaccggagat aatctggatg ttttacgcca tctgcaaaat
     3481 aattacgccg ataccgtcga tatgatctat atcgatcccc cttataacac cggatcggac
     3541 gggtttgtct atcccgatca ttttgaatat agcgatcggg cgttgcagga tatgtttggt
     3601 cttaatgata ccgaactggc acgtttaaaa tccattcagg gtaaatcgac gcactccgcg
     3661 tggttatctt tcatgtatcc gcgtcttttc ctggccagga agctcctgaa agataccggg
     3721 tttattttta tctctatcga cgataatgag tacgccaatc ttaaattaat gatggatgag
     3781 atttttggcg aaggcggatt tgtcaccaat gtgatgtgga agcgcaaaaa agagatttct
     3841 aacgactctg ataacgtttc catccagggg gaatacattc ttgtttacgc caaaaccggt
     3901 cagggcgctt tacgtttaga accgctttct aaagagtata ttcagaaatc ctataaagaa
     3961 ccgaccgaac agtttccaga agggaaatgg cgaccggtgc cgttaacggt gtcaaaaggg
     4021 ctgagcggcg gcggctatac ctataaaatt accacgccga acggtacggt acacgaaaga
     4081 ctatgggctt atcctgaagc cagttaccaa aaactggtgg ccgataatct ggtctatttt
     4141 ggcaaagata acggcggtat tccccagcga gtcatgtacg cgcatcacag taaagggcag
     4201 ccaacgacca attactggga taacgtagcg tcgaataaag aggggaaaaa ggagattctg
     4261 gatctcttcg gcgacaacgt ttttgatacg ccgaaaccga ccgcattatt gaagaaaatc
     4321 atcaagctcg ctatcgataa agacggcgtc gttctggact tttttgccgg ttccggcacc
     4381 acggcccatg cggtgatggc gctgaatgaa gaagatgggg ggcagcgcac gtttattctg
     4441 tgtactatcg atcaggcatt aagcaataac actatcgcga aaaaagcagg ttataacact
     4501 attgatgaaa tcagccgcga gcgaattaca cgcgttgcgg cgaagatccg cgccaacaat
     4561 cccgcgacca atagcgatct cggttttaaa cattatcgtt ttgccactcc gacacagcag
     4621 acgctggacg atctggatag cttcgatatt gctaccggcc attttatcaa taccagcggt
     4681 caactggccg ctttcaccga gtcaggattt accgacatga tcaatccttt ttccgccaga
     4741 ggattgggcg tgccgggcgg cgcaagcggc gaagagacct tattaacgac atggctggtc
     4801 gccgatggtt ataaaatgga tattgacgta cagaccgttg atttttccgg ctattgcgcc
     4861 aggtatgttg ataatacgcg cctgtatctg attgatgaac gatggggaac agagcagacc
     4921 cgcgatcttc tcaaccacat tggtacgcac cagcttccgg ttcagaccat tgtcatttac
     4981 ggctactctt tcgaccttga atccattcgt gaactggaaa tcggcttaaa acagcttgat
     5041 caaaaagtga acctggtgaa gcgttattaa gaggggatga tgatgaatat tttgctggaa
     5101 gaacttcccc atcaggaaca ggcgttagcg gcgattctgg cgagtttcac cggtatcgat
     5161 cacgcgcagg ccgatcataa tcactatgct aatccgctga ttaagggacg ttacgacgat
     5221 aaggccaata ttgacgttaa aatggagacc gggacgggca aaacctatgt ctatacccgg
     5281 ttgatgtatg aactgcatca gaagtatggc ctcttcaaat ttgtgctggt ggtgccgacg
     5341 ccagccatta aagaaggcgc gcggaacttt atcaccagcg attacgccag acagcatttt
     5401 tcacagttct acgaaaatac gcggatggaa ttttgcacca tcaacgccgg tgattttaaa
     5461 gtaaagtcgg ggcgtaaaaa ttttccggcc cagttattaa gttttactga tgccagccgt
     5521 cgtgatagcc atacgattca ggttttgctg atcaatgcgc aaatgctcaa ttccgccagt
     5581 atgacgcgag acgattacga tcaacgctac tgggcgggct gacgtcgcct gttaaagggc
     5641 tgcaaatgac gcgaccggtg gtcattattg atgaaccgca tcgttttgtg cgagataaca
     5701 aattttatcg agcgattcag gccattcagc cgcaaatgat cgtccgcttt ggcgctacct
     5761 tcccggatat tgtcgaaggt aagggtaaaa ataaatgtgt acgtaaagat tactatcgcc
     5821 ggcaaccgca gtttgatctc aacgcggtgg acagttttaa cgatggtttg gtgaaaggta
     5881 ttgatattta ttacccgaat ctccccgaag aacaggccaa caatcgttat atcgttgaca
     5941 gcgtcacggc aaagaaatta atcctccgac gggggagcaa aattgccgag gttggcgtgg
     6001 gcgaaaatct cgccgatgtc gatgcaggat ttgaaggcag tatcgaatat gccggcagta
     6061 aaatgttgtc gaacgatctg gagctggagg cagggatggc gctggtgcca ggaacctttg
     6121 gcgcgagcta ccaggaactg attattcagg acgctatcga taagcatttt gacactgagc
     6181 aggcaaattt cttacgcagc aatgagccag aaaataatgc cccgcgtatt aagaccttaa
     6241 gctttttctt tattgacagt attaaaagct atcgtgatga cgaaggttgg ttgaaactga
     6301 agtttgagtg tttactgaaa aagaaactga cgcaactgat tgacgattat cagcgcaaga
     6361 ccctgccgcg agaagtggag tatctgtcgt ttctgcaggc cacgctcgcc agcctgcact
     6421 cggataacca aaacgtccac gctggttact ttggcgaaga ccgcggaagc ggcgatgagg
     6481 cgatccaggc tgaggtagat gatattctga aaaataaaga gaagttgctc agtttttcag
     6541 accatcacgg caactgggaa acgcgccgct ttctgttttc aaaatggacg cttcgcgaag
     6601 gctgggataa cccgaatgtt tttgtcattg ctaaattacg ttcttccggt agcgagtcga
     6661 gcaaaattca ggaagtgggg cgcggcctgc ggctaccggt agatgaaaac ggccatcgcg
     6721 ttcatcagga agagtggccg tcccgactgt cgtttctgat tggttatgat gaaaaagcgt
     6781 ttgccagtat gctggttgat gagattaatc gcgacagcaa agttcagctt aacgagcaga
     6841 agctggatga ggcgatgatc acactcatcg tcaccgagcg acaaaaagtc gatcctgcgt
     6901 ttacggagct tcgtttgctg gaagatctgg atgataaaaa actgatcaac cggagtaatg
     6961 agtttaaacc cagcgtcacg cttaacgggg aaaccaaaag tggctttgcg tggctactgg
     7021 agttctaccc tgagctgacg caggcgcggg tgcgagcgga tcgcattcgt gacaataagc
     7081 ccgcctcccg actgcgagtc aggttacgca aagagaattg ggaacaactt agcagtatct
     7141 gggagcagtt ttcccgccgt tatatgctgc aattcgagcg tagcggcgct tctctggaac
     7201 agattgccgc cgaggtgctg cgcgatccgt cgctgtatat acgccagaag ccaagccagg
     7261 tgcaacaacg gctggtatcg aatgaagata atggccgttt tgaagtggcg cagcgggaag
     7321 gcgaattagc cgccagcgaa tttatggcgg gcatgaaata tggccatttt cttaagcaac
     7381 tggcgttacg caccagtctg ccgattaacg tcctgcaccc ggtgttaatg gcgatgctgc
     7441 gtgatgtttt gcacggagat tcacgctatt taagcgagat ctcgttggac aatatgaccc
     7501 gcgcattaca gacgcggatt aatgcgcatt ttgcgcagcg ccacgattat ctgcctctcg
     7561 attttcaggc ttcaacgtcg gtatttgatt ctacggcacg gcagttcaga gaggagatta
     7621 gcgctgaaat tgtggggaaa aatgtggatg agaatgcgat agacgatccc cgttctctct
     7681 atcaaatacc gccgttgcgt tatgacagcg tcgatccaga attgccgcta ttaaaatacg
     7741 attatccgca acaggtttct gtgtttggca aactgcctaa gcgggccatt cagatcccca
     7801 aatatacggg gggctctact acgccggatt ttgtgtaccg tattgagcgt caggacgccg
     7861 acagtgttta tttactggtt gaaactaaag cagaaaatat gcgcgtaggc gatcaggtta
     7921 ttcttgatgc gcaacgtaaa ttcttcgata tgctgcgtcg gcaaaatatc aatgtcgagt
     7981 ttgcggaagc gaccagcgcg ccggcggtat tttctaccat caatggcttg attgggggga
     8041 aggcaaacta acgggtttga atagacctta acggttatct ttttgatagg ccatataaaa
     8101 tggccgccgc gcagcgagcg ttgcggtcat tctcctgtgc taatcccccg tcccgtaaac
     8161 cgcgttgact tgaaggttat cgttttacgt ctattcttaa ctttcagcta agtgtatttt
     8221 gctgaaattg caaatagtct tgaagacgct gtttttttgt tttgccgtta tttttataac
     8281 ggccaggtag atattgccaa gtgaatgtaa ctaagggaga catgttatgc taaatagata
     8341 ctaccgtttc gctgtcgaaa aagacgaccc ctccgaagcg ccagagtcgg gcgataagcc
     8401 tgacagccag ccgcaaaaaa aatcgtaatt tatctggata ttccccgacg tttttacgtt
     8461 tggggaaaat aaccgtttcg tttcaacctg gttgcgaaca gtgaatattt tacacgaagt
     8521 gactatataa acgggaggga acatggagtt tgatgcattc tttttagcga gactccagtt
     8581 tgcctttacc gtctcttttc atattatttt ccccgcgatt acgattggct tagccagtta
     8641 cctggtggta ctggaaggtt tatggctaaa aacgcgtaat cctgtctggc gctcgctcta
     8701 tcagttctgg ctcaaaattt ttgccgtcaa cttcgggatg ggcgtggtct ccggtctggt
     8761 catggcttac cagttcggaa cgaactggag cggtttttcc cagttcgccg gcagtatcac
     8821 cgggccttta ttaacctatg aagtgctcac cgcattcttc ctggaagcgg gattcttagg
     8881 cgtgatgctt tttggctgga acaaagtcgg gccgggcctg catttcttgt ctacctgtat
     8941 ggtggcgttg ggcacgttaa tgtcgacgtt ctggattctg gcgtctaata gctggatgca
     9001 taccccgcag ggatttgaaa ttcataacgg tcaggtagtc ccggtggact ggttcgcggt
     9061 gattttcaac ccgtcgttcc cgtatcgcct gttgcatatg tccgttgcgg cgtttttaag
     9121 tagcgcgatg tttgtcggcg cgtccgcagc ctggcattta ctgaaaggta acgatacgcc
     9181 ggctatccgc cgtatgttct cgatggcgct atggatggcg gtcgtggtgg cacccgttca
     9241 ggcattgatt ggcgatatgc atggccttaa caccctgaag catcagccgg tcaaaatcgc
     9301 cgcgattgag gggcactggg aaaatacgcc cggcgagcca acgccgctta cgctggtagg
     9361 ctggccggat atggaggcgg aacggacccg ctatgcgctt gagatcccgg cgttgggcag
     9421 tctgatcctg acgcatagcc tggacaaaca ggtgcctgcg ctaaaagatt atcccaaaga
     9481 ggatcgcccc aaccctaccg tggtgttctg gtctttccgt ctgatggtgg gcatgggcgt
     9541 actgatgatc tttctggggc tggccagcct gtggctacgc taccgacgcc gcctgtatca
     9601 ttcgcggccc tttatgcact ttgcgctgtg gatggggccg tccgggctta tcgccatcct
     9661 tgccggatgg gtgacgactg aagtaggacg tcagccgtgg gtggtctatg gcctgctgcg
     9721 aacgcgtgat gcggtttccg cgcacagcac cttgcaaatg agcatcagtt tgctggcctt
     9781 ctttgtggtc tattccctgg tgtttggggt tggctatatt tatatgattc gtcttatcca
     9841 gaaagggccg cagccggcgg agacaccgac cgctgaaacc gatggcagac ccgcgcgtcc
     9901 tatctctgcc gtgggagaat cgcttgagca ggagaaacgc gaatgaccat cgatcttccg
     9961 gttatctggt ttgctattat cgtgttcgcc acgctgatgt atatcgtgat ggatggtttc
    10021 gatctgggcg tcggtatcct gtttccgttt attcgtgata aacacgatcg cgatgttatg
    10081 gtgaactcgg tcgcgccggt atgggacggg aacgaaacct ggctagtgct gggcggggcc
    10141 gggctttttg gcgcgttccc gttggcttat gccgtcatca ccgacgcgct gactatcccg
    10201 ctggtggtta tgctgcttgg tcttatcttt cgcggcgtcg cttttgaatt ccgttttaaa
    10261 gccaccgagt cgcatcgcgc gttctgggat aaatccttta tcgtcgggtc aatcctggcg
    10321 acctttgccc agggggttgt ggtgagcgcg gtggtgagcg gttttcaggt ggaagggcga
    10381 acctttagcg gttcgcagct tgactggctg acgccgttta atctgttctg cggcgtcggt
    10441 ctggtcgtca cctacgcgct gctgggcgct acctggctga ttatgaaaag cgaagatccg
    10501 ctgcatagcc ggatgtgcgc gctgtcgcgc ccgttgttga tcgtcttgtt gctggtgatg
    10561 gggggcgtca gcgtgtggac gccgctcacc catgacgaca tcgccgagcg ctggttcacg
    10621 ctgcccaatt tatactactt cctgccggtg cctgtgctgg tgttggcttt tagcgtctgg
    10681 ctatggcgca gcgtgaaaaa accacaatcc catgcgcgtc catttattct cacgctaggg
    10741 ctgatttttc tggggttcag cgggttagga atcagtattt ggccgaatat tattccaccg
    10801 gatatttcgc tgtatgccgc cgccgcgccg tcgcaaagtc aaagctttat gctggttggg
    10861 gcgctgataa tcatcccgat tattctggct tataccttct ggagctacta cgtcttccgt
    10921 ggaaaagtgc gacatggaga gggatatcac tgatggttaa agtgaaaaaa tggtcgcggc
    10981 gagtcgtatg gatggtcgcg atatggtgcg ccagcgtgct tctgctggcg ggcgtcggaa
    11041 tgttgttcag actgctcatg acctccgcag gatttcgctc ctgactgata cccccggacg
    11101 cgctttcgtc tctcgcgaaa gcgcgttttt atcgacagat cggcgtttat cgatcacctt
    11161 tgctcgcctt atctctcccc tcaatagcgg ttgataatta ttctcatctt tattgtcgtt
    11221 cccgggccgc agtgatatgg ttacacagtg gctaacgctc tggtataacg cagataaacg
    11281 gtattgataa tgtctccgat ctcctgtcac tcttccgccg ccccggcgat gaaaaagatc
    11341 ttttccgtca gcgacttcat cgcgtttggc gagcgttatg gcattgatta ccgcttccct
    11401 gcgttaccgc agtatacgca gagtagtccc gtacttcatg gcgatatcga agagatagcg
    11461 cttcccggcg ggatttgcat tacacgctcg gatgttcacg tgttacaacc ttatgaaacc
    11521 acctctcgcc atagcagtcc gctgtatatg ctggtggtgt tggaaggtaa cgtcgcgctg
    11581 gctgtcaatg agcagacctt tttgttgagc gcggggatgg cgttttgctc gcaactgagt
    11641 gagcagcaga cgatacgcgc ccatcacggc gcagacagta aattgcgcac cttatcgctg
    11701 ggaatgtacc cggacggcgg gtggcgggag cgtttgcctg tctcgctggc agacgagtgg
    11761 gaacgtagcg cggcctcggc gagggtctgg caggtgccgg agtttctgct ttcggggcta
    11821 cgttatgcgc agcagcccgg acctcatgcg gcgtcacgcc agttaatgct ggaaggcatc
    11881 atgctgcaat tgctgggcta tgcgttaaat ctatgtcagc ccgcaacgca aaaacgcgga
    11941 cttcccgtca ccggtgaata ccagcggctg gagctcattc ggcgtttact ggagcaaacg
    12001 ccggaaaaag cctacacgct gaacgaactg gcgcgtcggg cggcaatgag tccgagtagc
    12061 ctgcggtgca agtttcgcca tgcctatggg tgtaccgtgt ttgattatct gcgcgattgc
    12121 cgcctggcgc gcgcgcgtcg ttatctgatg gagggataca gcgtgcagca ggccgcctgg
    12181 atgtcaggct atcaacatgc cactaacttt gcgacggcat ttcgtcggcg ttatggctgc
    12241 tcgcccggcg agct
//
LOCUS       DAJVKX010000130        12245 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.130, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000130 DAJVKX010000000
VERSION     DAJVKX010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12245
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.130"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            142..2250
                     /gene="foxA"
                     /locus_tag="OPY25_003644"
     CDS             142..2250
                     /gene="foxA"
                     /locus_tag="OPY25_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrioxamine B receptor FoxA"
                     /protein_id="HCS0929148.1"
                     /translation="MPLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSP
                     VQSGATRLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDY
                     IVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPG
                     GIVSLTSRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQ
                     FTPLKEERYALMPSLTWRITDRTRLDLMAYLHRDPQGGSHSGLPYQGTVVPYNGGKIS
                     NTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQVYAAGWLNE
                     TALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPP
                     IDAFNPVYGAQPDYITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNID
                     KLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYSTAFTSTSFADENGNVLEPMKGKQ
                     WEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
                     DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEWLTLGSGI
                     RYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNS
                     LSYCYFGAERSIVGSVSWAF"
     gene            complement(2291..2923)
                     /locus_tag="OPY25_003645"
     CDS             complement(2291..2923)
                     /locus_tag="OPY25_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HCS0929149.1"
                     /translation="MEPFHAVVLTVSLFVLTFFNPGANLFVVVQTSLASGRRAGVITG
                     LGVATGDAFYSGLGLFGLATLITQCEAVFSLIKIVGGAYLLWFAWNSIRHQATPQMST
                     LQTPIAAPWTIFFRRGLMTDLSNPQTVLFFISIFSVTLSAETPTWARLMAWAGIVLSS
                     VIWRIFLSQAFSLPAVRRAYGRIQRIASRVIGAIIGMFALRLLYEGMTHR"
     gene            3155..3430
                     /locus_tag="OPY25_003646"
     CDS             3155..3430
                     /locus_tag="OPY25_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCS0929150.1"
                     /translation="MKTGYKVMLGALAFVVTNVYAAEIMKKTDFDKVASEYTKIGTIS
                     TTGEMSPLDAREDLIKKADEKGADVVVLTSGQTENKIHGTADIYKKK"
     gene            complement(3566..5191)
                     /gene="prpR"
                     /locus_tag="OPY25_003647"
     CDS             complement(3566..5191)
                     /gene="prpR"
                     /locus_tag="OPY25_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HCS0929151.1"
                     /translation="MTTAHSAPRDNSDKPVIWTVSVTRLFELFRDISLEFDHLATITP
                     IQLGFEKAVTYIRKKLATERCDAIIAAGSNGAYLKSRLSIPVILIKPSGFDVLQALAK
                     AGKLTSSIGIVTYQETIPTLLAFQKTFHLCLEQRSYVTEEDARGQINELKANGIEAVV
                     GAGLITDLAEEAGMTAIFIYSAATVRQAFHDALDMTRLTRRQRVDYPSGKGLQTRYEL
                     GDIRGQSPQMEQLRQTITLYARSRAAVLIQGETGTGKELAAQAIHQTFFHRQPHRQNK
                     PSPPFVAVNCGAITESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEM
                     PLPLQTRLLRVLEEKAVTRVGGHQPIPVDVRVISATHCDLDREIMQGRFRPDLFYRLS
                     ILRLTLPPLRERQADILPLAESFLKQSLAAMEIPFTESIRHGLTQCQPLLLAWGWPGN
                     IRELRNMMERLALFLSVDPAPTLDRQFMRQLLPELMVNTAELTPSTVDAHTLQDVLAR
                     FKGDKTAAARYLGISRTTLWRRLKAGAKDQSGN"
     gene            5457..6344
                     /gene="prpB"
                     /locus_tag="OPY25_003648"
     CDS             5457..6344
                     /gene="prpB"
                     /locus_tag="OPY25_003648"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HCS0929152.1"
                     /translation="MSLHSPGQAFRAALAKENPLQIVGAINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCPLPLLVDADIGFGSSAFNVARTVK
                     SIAKAGAAALHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDARTDPNFVIMARTD
                     ALAVEGLEAALDRAQAYVDAGADMLFPEAITELSMYRQFADVAQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEKVYTVLRQEGTQKNVIDIMQTRNELYES
                     INYYQFEEKLDALYRNKKS"
     gene            6467..7636
                     /gene="prpC"
                     /locus_tag="OPY25_003649"
     CDS             6467..7636
                     /gene="prpC"
                     /locus_tag="OPY25_003649"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HCS0929153.1"
                     /translation="MTDTTILQNNTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELNAYKSKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPTQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     VYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSEEGGSLKMYHIADRLETVMWETKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYTGPEDRVFVPIEKRC"
     gene            7674..9125
                     /locus_tag="OPY25_003650"
     CDS             7674..9125
                     /locus_tag="OPY25_003650"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-methylcitrate
                     dehydratase/aconitate hydratase"
                     /protein_id="HCS0929154.1"
                     /translation="MSAHISNVRPDFDREIVDIVDYVMNYEITSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGARVPGTQFQLDPVQAAFNISAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVAAGKAPLTMKQVLSGMIKAHEIQGCIAL
                     ENAFNRVGLDHVLLVKVASTAVVAEMLGLTRDEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAKTWGFYDVSFKGETFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACLRIIDK
                     KGPLNNPADRDHCIQYMVAVPLLFGRLTAADYEDEVAQDKRIDALREKIVCYEDPAFT
                     ADYHDPEKRAIGNAITVEFTDGSRFGEVVVEYPIGHARRRADGIPKLIEKFKINLARQ
                     FPTRQQQRILDVSLDRARLEQMPVNEYLDLYII"
     gene            9166..11052
                     /gene="prpE"
                     /locus_tag="OPY25_003651"
     CDS             9166..11052
                     /gene="prpE"
                     /locus_tag="OPY25_003651"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HCS0929155.1"
                     /translation="MSFSEFYQRSINEPEAFWAEQARRIDWRQPFTQTLDHSRPPFAR
                     WFCGGTTNLCHNAVDRWRDKQPEALALIAVSSETDEERTFTFSQLHDEVNAVAAMLLS
                     LGVQRGDRVLVYMPMIAEAQITLLACARIGAIHSVVFGGFASHSVAARIDDARPALIV
                     SADAGARGGKILPYKKLLDDAIAQAQHQPKHVLLVDRGLAKMSWVDGRDLDFSTLRQQ
                     YLGASVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTYPDCGVWWKIVEKYQVNRMFSAP
                     TAIRVLKKFPTAQIRNHDLSSLEALYLAGEPLDEPTASWVTETLGVPVIDNYWQTESG
                     WPIMALARALDDRPSRLGSPGVPMYGYNVQLLNEVTGEPCGINEKGMLVIEGPLPPGC
                     IQTIWGDDARFVKTYWSLFNRQVYATFDWGIRDAEGYYFILGRTDDVINIAGHRLGTR
                     EIEESISGYPNVAEVAVVGIKDALKGQVAVAFVIPKQSDTLADREAARDEEKAIMALV
                     DNQIGHFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLQQIRQ
                     AIEE"
     gene            complement(11156..12130)
                     /gene="hemB"
                     /locus_tag="OPY25_003652"
     CDS             complement(11156..12130)
                     /gene="hemB"
                     /locus_tag="OPY25_003652"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HCS0929156.1"
                     /translation="MTDLIHRPRRLRKSAALRAMFEETTLSLNDLVLPIFVEEELDDY
                     KAIDAMPGVMRIPEKQLAREIERIANAGIRSVMTFGISHHTDDTGSDTWKEDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLANLGKQAVIAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFTDTAIMSYSTKFASSFYGPFREAAGTALKGDRKT
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDVLREIRERTELPLGAYQVSGEY
                     AMIKFAAMAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKNILR"
BASE COUNT         2810 a         3221 c         3473 g         2741 t
ORIGIN      
        1 ccccgccaga gcggtaatat ccgccgctaa cccggttttc tgccgctttg ggtgattttt
       61 tatcattgcg cataggcaat ctggcgttac gcatagtggt tcgttatctc taaagggtaa
      121 taattcttat ttacaataaa gatgcctttg gagatgttca tgtttgcgac aacgcgtatg
      181 gcgctattga taggcggagc tatcggcggc gcgacttttc ctctttttgc ccaggaaacc
      241 acaaaaaatg ataccgtcat tgtcacctcg cccgttcaga gtggcgcgac caggctggcg
      301 acgccagata ttgaaacgcc gcagtcggta tccattatta cccgccagca gtttgaagag
      361 cagggcgcaa ccagcgtgcg tcaggcggtc agctacaccc caggcgtata cagtaaccag
      421 ataggcgcct ctaaccgctt tgattacatc gtattgcgtg gtttttcgga cggtagtctg
      481 gataacgtct atctcgacgg gttaaaaatg atgggcgaca ccaattcgca cagttcgttg
      541 gtggttgacc cctggtttct ggaagatatc gaggtggtac gcggcccggc gtccgttctg
      601 tatggacgtt catcgccagg cggcattgtc tcgttgacgt cgcgaaaacc ggcgtttgat
      661 gccggaggag aagtgaagct gtttgccggc aataacaacc agcgcggggc ggcttttgat
      721 gtgaccggcc cactggatga caatgaacgt gtggcggcgc gtcttagcgg catgacacgt
      781 tacgccgatt cgcagtttac gcccctgaaa gaggaacgtt atgcgctgat gccgagcctg
      841 acctggagaa ttaccgatcg gacgcgtctt gatcttatgg cctatctgca ccgtgatccg
      901 caaggcggta gccactccgg actgccttat caaggcacgg ttgtacctta taacggcgga
      961 aaaatttcta acactttctt tgaaggtgaa gatgactacg acaaatacga tcgccgtgaa
     1021 aatatggtgg gttataacat tgagcatctg ttcgataacg gctggtcggt acggcaaaaa
     1081 ttgcgttatt tgcataccaa agtgacgttg aatcaggtct atgccgcagg ttggttgaat
     1141 gaaacggcgc tgaatcgcgg ctattccggc tccggggaga aaatgtcggc tatcgcgctg
     1201 gataatcagc tcgacggcag cgtggatacc ggggcgatta atcatcgtct gctggtgggg
     1261 atcgattatc aggatcgcag taatcatact actggctatt atggcgcgtt tccgccgatt
     1321 gacgctttca accctgttta tggcgctcag ccggattaca ttacgttgta tagccgtgaa
     1381 aaacataagc tgcggcagac cggatactat ttacaggatc agatgtcatg ggatcgctgg
     1441 cgctttacgt tgggcggtcg ttacgatcgg gtcagcgtgt ctaacatcga caaacttcat
     1501 gattcacgca gcgatctcga taaaaacaac gtcagcaccc gtgccgcgtt gctttatctg
     1561 ttcgacaatg gcgtcgcccc ctatctcagt tattctaccg cgtttacgtc gaccagcttc
     1621 gccgacgaaa acggcaatgt gctggaaccg atgaaaggca agcagtggga ggcgggggta
     1681 aaatacgaac cgctgggggg gaacagccag tttagcgccg ccgtgtatcg tattaaccaa
     1741 accaatatcg cgaccaaaga agaacctacc gatccgtacc gctcgattgg tgaaattgag
     1801 tctaaagggg ttgaactgga ggccattagc catttgtcgg atagcgtccg tttgcaggcg
     1861 gcgtatacct atactgatat ccgttataag aaaagtagcc cgcaagagca ggggaagcgc
     1921 gcggtttatg ctccacggaa ccaggccagc gcctggctaa gctacgatgt gaaaagcggt
     1981 ctgttagagt ggctgacttt gggctccggc atccggtacg tcaacggcgt gaccagcgat
     2041 cgcctgaata cccacacgtt gccgtcctat acactggtcg acatggtggt tgggtatgat
     2101 ttatccagca ttgggttaaa tggcttgagc gcccagctca acgtaaataa tctgacggac
     2161 aaacgctatg tcgctgcctg taattcgctc tcttattgtt attttggcgc cgagcgtagc
     2221 attgtaggca gcgtgtcatg ggcgttttga taacgcttat cgtccggtag caaaggctac
     2281 cgggcaaaca ttagcggtgc gtcatgcctt catagagaag tctgagcgca aacatcccga
     2341 taatggcgcc gataacacgg ctggcaatgc gctgtattcg tccataagcg cggcggactg
     2401 cggggagcga aaaggcctgg ctgagaaaaa tacgccagat aacggatgac agcacaattc
     2461 cggcccaggc cattaacctt gcccatgtgg gcgtttctgc gctaagcgtt acggaaaaaa
     2521 tactgataaa aaacagtacg gtttgcggat tggataaatc ggtcattaat ccccggcgaa
     2581 agaaaattgt ccacggggcg gcaatcggcg tctggagcgt gctcatttgc ggcgtcgcct
     2641 ggtggcgaat actgttccag gcgaaccata ataaataggc gccgccgaca attttgataa
     2701 gagaaaatac cgcttcgcat tgcgtaatga gcgtcgccag accgaaaagc cccagcccgg
     2761 aataaaaggc gtctcccgtg gcgacgccca ggccggtgat gactcccgcc cggcgtcctg
     2821 atgcgaggct ggtttgcacc accacaaaca gattcgcgcc gggattaaaa aaggttaaca
     2881 caaacagact gacggtaagc acaacggcat gaaacggctc catagacaac tcttcccata
     2941 gcctcaagaa ataacgttca tcttattaat agtcaaacca gatgattgcg agtgagatca
     3001 caaagcaggg gcgttttaat ccgcgtcgtt atgccgagtg agcgggggct gactggattt
     3061 ttccagcaat ctacactact tatttaatca gtccgaacgg cctttttgtt ctgataaagc
     3121 gatgatggcg taataataaa acgagggttt tgctatgaaa actggctaca aggttatgct
     3181 tggcgcatta gcgtttgtcg tgacaaacgt ttatgccgca gaaatcatga aaaaaacgga
     3241 ctttgataaa gtcgcctccg aatacacgaa aattggcacg atttccacca ccggggaaat
     3301 gtcgccgctg gacgccagag aagatttaat caaaaaggcg gatgaaaaag gggcggatgt
     3361 ggtggtgctg acgtccgggc agacagaaaa taaaattcat ggtacggctg atatttataa
     3421 aaagaaataa aagcgttgca tcataaaaat acccgcctgg gtttccggcg ggtattttta
     3481 ttcctggcaa ccggcatccg ttttgccgga tgacggcctg cagtaaacgt agcgccatca
     3541 ggcattcagg acgctgtcat ttgtcttaat tacccgactg gtctttggca cctgctttta
     3601 aacgacgcca cagagtggtg cggctaatcc ccagataacg cgccgccgcg gtcttatcgc
     3661 ccttaaagcg cgccagtaca tcctgtaacg tgtgcgcatc cacggttgaa ggcgtcagct
     3721 ctgctgtgtt caccataagc tcaggtaata actgccgcat aaattgcctg tccagcgttg
     3781 gtgcgggatc gacgcttaaa aaaagcgcca ggcgctccat catattacgc agttcgcgaa
     3841 tattaccggg ccagccccag gccagcaaaa gcggctgaca ctgtgtcaat ccatgacgta
     3901 tcgattcggt aaacggaatt tccatcgccg ccagcgactg ttttaaaaag ctttccgcca
     3961 gcggcaaaat atcagcctgc cgctcgcgca aaggaggaag cgtcagacgc agaatactca
     4021 ggcgataaaa gagatcgggg cgaaaacgtc cttgcattat ctcccgatcc agatcgcaat
     4081 gcgtagcgct gatcacccgg acatccaccg ggatcggttg gtgtccgccg acgcgagtga
     4141 cggctttttc ctccagtacg cgcaagagtc gggtttgtaa cggcaagggc atttcgccga
     4201 tttcatccag aaacagcgtg ccgccgtgtg cgatttcaaa cagccccgcc cggcctcctc
     4261 gtcgtgaacc ggtaaacgcg ccctcttcat aaccaaacag ttccgcctcc agcaatgact
     4321 cggtaatcgc gccgcaattg acggcgacaa agggagggga tggcttattc tgacggtgag
     4381 gctggcggtg aaaaaacgtc tggtgaatcg cctgcgccgc cagctctttt ccggtccctg
     4441 tttccccctg aatcagcact gccgcacggg agcgggcata gagcgtaatc gtctggcgga
     4501 gctgctccat ttgcggcgac tggccgcgta tatcgcccag ttcataccgg gtttgtaatc
     4561 ccttgccgga tgggtaatcc acgcgctggc gccgtgtcag acgggtcata tccagcgcat
     4621 catgaaaagc ctgacgaacg gtcgccgcgg aataaataaa gatggcggtc atacccgctt
     4681 cttccgccag atcggtaatt aatcccgcgc cgacgacggc ctcaataccg ttggccttaa
     4741 gttcgttaat ttgcccgcgc gcgtcctctt cggtgacata gcttcgctgt tcaagacaga
     4801 ggtgaaacgt tttctgaaag gcaagtaaag tcggaatggt ctcctgatag gtcacgatac
     4861 cgatagacga ggtgagcttt cccgctttcg ccagcgcctg taatacgtcg aatccgctgg
     4921 gcttgatgag gatcaccggt attgacaggc gactttttaa ataggccccg ttcgaacccg
     4981 ccgcgataat cgcgtcgcag cgctcggtcg ccagtttttt gcgaatgtag gtcaccgcct
     5041 tttcaaagcc gagttgaata ggcgtgatgg tcgccagatg atcgaattcc aggctgatat
     5101 cccgaaacag ttcgaataga cgcgttacgg agaccgtcca gatcaccggt ttatcgctat
     5161 tatcgcgcgg agcgctgtga gcagtcgtca tcgcagtagg ttcatcttta aggggcgatt
     5221 ttttgtttta aacgtgtttc ataaatgttg caatgaaacg gagcgattcg tttcatgaaa
     5281 cgttagctga cacgtttttc ttttccctta atcgcgctta ttcataacag gaatgactgt
     5341 aattacctgt ttttaaatct cattgtattt aattttctcg ctgcctcttt gcctggcata
     5401 gcctttgctt tggtgaatac atcttgaata acaatttact aacatgagga cgaattatgt
     5461 ctttacattc gccggggcag gcatttcgcg ccgcgctcgc taaagagaat ccattacaaa
     5521 ttgtcggcgc tattaatgcc aaccatgctc tgttggccca acgggccggg tatcaggcta
     5581 tctatctttc tggcggcggc gtagcggcgg gctcgctcgg actgccggat ctggggattt
     5641 cgacgctgga tgatgtgtta accgatatcc ggcgcatcac ggatgtttgc ccgctgccgc
     5701 tgttggtgga tgcggatatt ggctttggct cctccgcctt taatgtcgcg cggacggtaa
     5761 agtccatagc caaagcgggc gccgccgcgc tgcatattga agaccaggtt ggcgctaagc
     5821 gctgtggaca ccgtccaaac aaagcgatcg tctcgaaaga ggagatggta gacagaattc
     5881 gggcggcagt ggatgcgcgc accgatccga actttgtgat catggcgcgt accgatgcgc
     5941 tggcggtgga agggctggag gcggctctcg atcgcgcgca ggcttacgtg gatgcggggg
     6001 ctgacatgct gttcccggag gcgatcaccg aactgtcgat gtaccgccag ttcgccgacg
     6061 tggcgcaggt gccgatcctc gccaacatca ctgagtttgg cgcgacgccg ctgtttacga
     6121 ccgacgagtt gcgcagcgca cacgtggcga tggcgctcta tccgctgtcg gcgtttcgcg
     6181 ccatgaaccg cgccgcagaa aaagtctata ccgtgctgcg ccaggaaggg acgcaaaaga
     6241 acgtgatcga catcatgcag acccgcaacg agctgtacga aagcatcaat tactaccagt
     6301 tcgaagagaa gctggacgcg ctgtacagga ataaaaaatc gtagcctgtg ggcctgataa
     6361 ggcgaagccg ccatcaggca atgccggatg gcactacgtt tatcccgcct acggtacggc
     6421 ctacacgcct caatacccta cacattacaa taatgacgag gacaatatga cagacacgac
     6481 gatcctgcaa aacaacacgc atgtcattaa gcctaaaaaa tcggtcgcgc tttccggcgt
     6541 acctgccgga aataccgctc tgtgtaccgt gggaaaaagc ggtaacgatc tgcactatcg
     6601 cggttacgac attctcgatc tggcggagca ctgcgaattt gaagaagtcg cgcatttact
     6661 gatccacgga aaattaccga cccgcgacga gctgaacgcg tataaaagca agttaaaagc
     6721 gctgcgcgga ttacccgcca atgtccgtac cgttctggaa gcgttaccgg cggcctcgca
     6781 cccgatggac gtgatgcgta ccggcgtttc cgcgctgggc tgcaccctgc cggaaaaaga
     6841 gggacatacc gtctccggcg cgcgcgatat tgccgataag ctgttggctt cgctcagctc
     6901 tatccttctt tactggtatc actacagcca caacggcgaa cgtattcagc cggaaaccga
     6961 cgatgattcc atcggcggcc atttcctgca tctgctgcac ggtgaaaagc caacccaaag
     7021 ctgggaaaag gcgatgcata tttcgctggt gctgtacgcc gagcatgagt tcaacgcctc
     7081 gacgtttacc agccgggtaa ttgccgggac cggctcggat gtctactccg cgattatcgg
     7141 cgcgattggc gcgctgcgcg gcccgaaaca cggcggagcg aatgaggtgt cgctggaaat
     7201 tcaacagcgt tatgaaacac cggacgaggc agaggcggat atccgtaaac gcgtggaaaa
     7261 caaagaggtg gtgattggct ttggacatcc ggtttacacc atcgccgacc cgcgccacca
     7321 ggtgatcaaa cgggtggcga aacagctttc agaagaaggc ggctcgctga agatgtacca
     7381 catcgccgac cgtctggaaa cggtgatgtg ggagaccaaa aagatgttcc cgaatctcga
     7441 ctggttttcg gcggtctcct acaacatgat gggcgtccct accgaaatgt tcaccccgct
     7501 gtttgtcatc gcccgcgtta ccggctgggc ggcgcacatt attgaacagc gtcaggacaa
     7561 caaaattatt cgtccttccg ccaattatac cggcccggaa gatcgcgtat ttgtgccgat
     7621 cgaaaagcgt tgctaattaa aacctctaaa tataaaaaca ggagttgtac cctatgtccg
     7681 cacatatttc gaacgttcgc ccagactttg accgtgaaat cgttgatatc gttgattacg
     7741 ttatgaatta cgagatcacc tcaaaggtgg cgtacgacac tgcgcattac tgcctgctcg
     7801 acacgctcgg ctgtggtctg gaagcgctgg aatacccggc ctgtaaaaaa ttgcttgggc
     7861 caatcgtgcc aggcacggtg gtgcccaacg gcgcacgcgt gccgggcacc cagttccagc
     7921 tcgatccggt acaggcagcc tttaacatta gcgcgatgat ccgctggctc gattttaacg
     7981 atacctggct tgccgccgag tggggccatc cttctgataa cctcggcggt attctggcga
     8041 cggctgactg gctgtcacgc aacgccgtcg ccgccggcaa agcgccgctg accatgaaac
     8101 aggtattgag cgggatgatc aaagcccatg aaattcaggg ctgcatcgcg ctggaaaacg
     8161 ccttcaaccg tgtcgggctt gaccatgtgc tgctggtcaa agtggcctcg accgcggtgg
     8221 tcgctgaaat gctggggctg acgcgcgatg agatcctcaa cgcggtatcg ctggcgtggg
     8281 tggatgggca gtcgttgcgc acttatcgtc atgcgccgaa taccggtacg cgcaaatcct
     8341 gggcggcggg cgatgcgact tcgcgcgcgg tacgtctggc gctgatggcg aaaaccggcg
     8401 agatgggcta tccctcggcg ctcaccgcca aaacctgggg cttctacgac gtttcattca
     8461 aaggtgaaac gttccgtttc cagcgccctt acggctccta cgtgatggaa aacgtgctat
     8521 ttaaaatttc tttcccggca gaattccact cgcaaaccgc cgtcgaagcg gcgatgacac
     8581 tgtatgagca gatgcaggcc gcgggcaaaa cggcagcgga tatcgagaaa gtgactatcc
     8641 gcacccacga agcctgtctt cgcattatcg ataaaaaagg cccgctcaat aacccggcgg
     8701 accgcgatca ctgtatccag tatatggtcg ccgtgccgtt gctgttcgga cggttaaccg
     8761 cggcggatta tgaagacgag gtggcgcagg acaagcgtat tgacgccctg cgcgagaaaa
     8821 tcgtgtgcta tgaggacccg gcttttaccg ccgactatca cgacccggaa aaacgtgcta
     8881 tcggcaatgc gatcaccgtg gagtttactg atggctcacg ctttggcgag gttgtcgtgg
     8941 agtatccgat tggtcatgcg cgtcgccgcg ccgacggtat tccgaagctt atcgaaaaat
     9001 ttaaaattaa cctggcgcgt cagttcccga ctcgccagca gcaacgcatt ctggatgtct
     9061 ccctggacag agcccgcctg gagcagatgc cggttaacga atacctcgat ttatatatca
     9121 tctgagccag ccagcagtaa ggcgtaagtt caacaggaga gcgtgatgtc ttttagcgaa
     9181 ttttatcagc gttccattaa cgaaccggag gcgttctggg ccgagcaggc ccggcgtatc
     9241 gactggcgac agccgtttac gcagacgctg gatcatagcc gtccaccgtt tgcccgctgg
     9301 ttttgcggcg gcaccactaa cttatgtcat aacgccgtcg accgctggcg ggataaacag
     9361 ccggaggcgc tggcgctgat tgccgtctca tcagagaccg atgaagagcg cacatttacc
     9421 ttcagccagt tgcatgatga agtcaacgct gtggccgcta tgctgctgtc gctgggcgtg
     9481 cagcgtggcg atcgcgtatt ggtctatatg ccgatgattg ccgaagcgca gataaccctg
     9541 ctggcctgtg cgcgcattgg cgcgatccat tcggtggtct ttggcggttt tgcctcgcac
     9601 agcgtggcgg cgcgcattga cgatgccaga ccggcgctga ttgtgtcggc ggatgccgga
     9661 gcgcgtggcg gtaaaattct gccgtataaa aagctgcttg atgacgctat tgcgcaggcg
     9721 cagcatcagc cgaaacacgt tctgctggtg gacagagggc tggcgaaaat gtcgtgggtg
     9781 gatgggcgcg atctggattt ttccacgttg cgccagcagt atctcggcgc gagcgtgccg
     9841 gtggcgtggc tggaatccaa tgaaacctcg tgcattcttt acacctccgg cactaccggc
     9901 aaaccgaaag gcgtccagcg cgacgtcggc ggttatgcgg tggcgctggc aacctcgatg
     9961 gacaccattt ttggcggcaa ggcgggcggc gtattctttt gcgcatcgga tatcggctgg
    10021 gtcgtcggcc actcctatat cgtttacgcg ccgctgctgg caggcatggc gactattgtt
    10081 tacgaaggac tgccgacgta cccggactgc ggggtctggt ggaaaattgt cgagaaatac
    10141 caggttaacc ggatgttttc cgccccgacc gcgattcgcg tgctgaaaaa attcccgacg
    10201 gcgcaaatcc gcaatcacga tctctcctcg ctggaggcgc tttatctggc cggtgagccg
    10261 ctggacgagc cgacggccag ttgggtgacg gagacgctgg gcgtaccggt catcgacaat
    10321 tattggcaga cggagtccgg ctggccgatc atggcgctgg cccgcgcgct ggacgacagg
    10381 ccgtcgcgtc tgggaagtcc cggggtgccg atgtacggtt ataacgtcca gctactcaat
    10441 gaagtcaccg gcgaaccctg cggcataaat gaaaaaggca tgctggtgat cgaagggccg
    10501 ctgccgccgg gttgtattca gactatttgg ggcgacgatg cgcgttttgt gaagacttac
    10561 tggtcgctgt ttaaccgtca ggtttatgcc actttcgact ggggaatccg cgacgccgag
    10621 gggtattact ttattctggg ccgtaccgat gatgtgatta atattgcggg tcatcggctg
    10681 gggacgcgag aaatagaaga aagtatctcc ggttacccga acgtagcgga agtggcggtg
    10741 gtggggataa aagacgctct gaaagggcag gtggcggtgg cgtttgtcat tccgaagcag
    10801 agcgatacgc tggcggatcg cgaggcggcg cgcgacgagg aaaaagcgat tatggcgctg
    10861 gtggataacc agatcggtca ctttggtcgt ccggcgcatg tctggtttgt ttcgcagctc
    10921 cccaaaacgc gttccggaaa gatgcttcgc cgcacgatcc aggcgatctg cgaaggccgt
    10981 gatccgggcg atctgacaac cattgacgat cccgcgtcgt tgcagcaaat tcgccaggcg
    11041 atcgaggaat agccgtaagc cggataagcc gcgtccggca acgggttaga ctcagcgact
    11101 gaatagtggg gtgtaaagtc gggaaagggc ggcagcgcgc cgccctgtaa cagaattaac
    11161 gcagaatatt tttctcagcc agatccagtg cgaagtagct gaaaatcaaa tcggcgccgg
    11221 cgcgtttaat cgagcccaga ctttccagca cgaccttttc ttcatcgatg gcgccagcca
    11281 tagcagcaaa tttaatcatg gcgtattcac cgctcacctg gtaagcgcca agcggcaact
    11341 ctgtgcgttc gcgaatttca cgcagcacgt ccagatacgc gccggccggt ttcaccatta
    11401 agcaatccgc gccctgggct tcgtcgagca gtgattcgcg aatcgcttca cggcggttca
    11461 tcggattcat ttgatacgtc ttgcggtcgc cttttaacgc ggtacccgct gcttcacgga
    11521 aggggccgta gaaagaagag gcgaacttgg tggagtagga cattattgcc gtatcggtaa
    11581 aaccggcggc atccagcgct tggcggatag cctggacttg tccatccatt gccgcggagg
    11641 gcgcaataaa atctgctcca gccgccgccg cgataacggc ctgcttgccg aggttggcca
    11701 gcgtcgcatc gttatccaca ccgtgttcgc acaacacgcc gcagtggccg tgcgaggtgt
    11761 attcgcagaa gcaggtgtcg gacatgacga tcatctccgg cacggtttgc ttacagatgc
    11821 gggacattct tgccaccagg ccgtcttctt tccaggtatc gctgccggtg tcatcagtat
    11881 ggtgagaaat gccgaaggtc ataacggaac gaatgccagc atttgcgata cgttcaatct
    11941 ctcgcgccag ctgcttttcc gggatacgca ttacgccggg catggcatca atagctttgt
    12001 aatcgtcgag ttcttcttca acaaagatcg gcaacaccag gtcgttcagg ctaagtgttg
    12061 tctcttcaaa catagcgcgc agcgcagcgg atttgcgcag gcggcgaggg cgatggataa
    12121 ggtctgtcat ggtctgcctg atgtttgtgg aatcgaaggc ccagtatacc tgaatctgca
    12181 ggcagatgtt ttacgaaaac ggtccttaac gtagcaggcg cagccccggc ggcggcagaa
    12241 catgg
//
LOCUS       DAJVKX010000131        12142 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.131, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000131 DAJVKX010000000
VERSION     DAJVKX010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12142
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.131"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(42..836)
                     /gene="thyA"
                     /locus_tag="OPY25_003653"
     CDS             complement(42..836)
                     /gene="thyA"
                     /locus_tag="OPY25_003653"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCS0929157.1"
                     /translation="MKQYLELIQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLLEGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVGDFVWTGGDTHLYSNHMEQTHL
                     QLSREPRALPKLVIKRKPDSLFDYRFDDFEIEGYDPHPGIKAPVAI"
     gene            complement(843..1718)
                     /gene="lgt"
                     /locus_tag="OPY25_003654"
     CDS             complement(843..1718)
                     /gene="lgt"
                     /locus_tag="OPY25_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCS0929158.1"
                     /translation="MTSSYLHFPDFDPVIFSIGPVALHWYGLMYLVGFVFAMWLAVRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPLFLDNPLYLFRVWDGGMSF
                     HGGLIGVILVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPDF
                     RFAMLFPGSRAEDIALLPSHPQWQPIFDTYGVLPRHPSQLYELALEGVVLFIILNLFI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIIAGAI
                     MMVWAYRRRPQQHVS"
     gene            complement(1931..4177)
                     /gene="ptsP"
                     /locus_tag="OPY25_003655"
     CDS             complement(1931..4177)
                     /gene="ptsP"
                     /locus_tag="OPY25_003655"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCS0929159.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVALAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQVT
                     ALFGQYRQTRIRALPAAPGVAIATGWQDATMPLMEQVYEASTLDTSLERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDARLRRELFAEVDKGAVAEWAVKKII
                     EKFAEQFAALTDNYLKERAGDLRTLGQRLLFHLDDSVQGPNAWPERFILVADELSATT
                     LAELPQDRLAGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLVVDGYRGE
                     LLVDPEPVLIQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLSILLPMVTSIDEVD
                     EARRLIERAGREVEEMIGYAIPKPRIGIMLEVPSMVFMLPHLANRIDFISVGTNDLTQ
                     YILAVDRNNTRVASIYDSLHPAMLRALSMIAQEAEKHGLDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRHIDFEDAQTLARRSLEAQMATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(4190..4720)
                     /gene="rppH"
                     /locus_tag="OPY25_003656"
     CDS             complement(4190..4720)
                     /gene="rppH"
                     /locus_tag="OPY25_003656"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HCS0929160.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQD
                     NPPKLQSAPAYRRKRG"
     gene            5403..6098
                     /gene="mutH"
                     /locus_tag="OPY25_003657"
     CDS             5403..6098
                     /gene="mutH"
                     /locus_tag="OPY25_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HCS0929161.1"
                     /translation="MSALCPLLTPPASEALLLAQARQLSGYTLGELAVMAGITTPKDL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEE
                     LMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFT
                     QALLARHFLLQNP"
     gene            6280..6993
                     /locus_tag="OPY25_003658"
     CDS             6280..6993
                     /locus_tag="OPY25_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HCS0929162.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RNHARRLGLAAAMVMRLALLASIAWVTRLTNPLFELFGEAISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARPIGEFVDRHPSVKMLALSFLILVGFTLILESFDVHVPKGYIYFAM
                     FFSIAVESLNLLRNKKNPL"
     gene            7164..7382
                     /locus_tag="OPY25_003659"
     CDS             7164..7382
                     /locus_tag="OPY25_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCS0929163.1"
                     /translation="MKKWAVVISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPQVDD
                     DTGLVSYTDTQGNEMQINRDEVSQIIER"
     gene            7573..8613
                     /locus_tag="OPY25_003660"
     CDS             7573..8613
                     /locus_tag="OPY25_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HCS0929164.1"
                     /translation="MHYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYTIANGI
                     NLIDAAEMYPVPPRPETQGLTESYIGNWLAKRGNREKLIIASKVSGPARNNDQGIRPH
                     QALDRKNIREALHDSLTRLQTDYLDLYQVHWPQRPTNCFGKLGYNWADSMPVVSLLET
                     LDALSEFQRAGKIRYIGVSNETAFGVMRYLHLAEKHDLPRIVTIQNPYSLLNRSYEVG
                     LAEVSQYEGVELLAYSCLAFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQAQKAVAA
                     YVDIAKRHNLDPAQMALAFVRRQPFVASTLLGATTMAQLKTNVESLHLTLSEEVLAEI
                     EAVHQVYTYPAP"
     gene            complement(8700..9902)
                     /gene="lplT"
                     /locus_tag="OPY25_003661"
     CDS             complement(8700..9902)
                     /gene="lplT"
                     /locus_tag="OPY25_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HCS0929165.1"
                     /translation="MSESVRTNTSIWSKGMLSVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPDWSQPVLQMVFVGAYILFAPFVGQIADSFAKGRVMMVANGLKLAGAAGICLGVNP
                     FVGYTLVGIGAAAYSPAKYGILGELTTGDKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVIAALVACALAYAGAVAANLFIPKLVAARPGQSWRLSAMTRSFFCACVVLWRNGET
                     RFSLVGTGLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAVGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVAIFSLQHALLPAYALLLLIGMLGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGLYSLAVLVGVPAVAIGIGFGVLFALAIAALWI
                     WQRRQASY"
     gene            complement(9895..12054)
                     /gene="aas"
                     /locus_tag="OPY25_003662"
     CDS             complement(9895..12054)
                     /gene="aas"
                     /locus_tag="OPY25_003662"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HCS0929166.1"
                     /translation="MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLIAPNHVSFIDGML
                     LALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVI
                     FPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRI
                     QLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYG
                     AGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAV
                     SRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSAEKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPEL
                     AVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE"
BASE COUNT         2953 a         3426 c         3092 g         2671 t
ORIGIN      
        1 ccgacgcgcg atggcgtcgg ttatggcagg atcgtcagcg cttagatagc gaccggcgct
       61 ttaataccgg ggtgcggatc atagccttca atttcgaaat catcgaaccg gtagtcaaaa
      121 agcgaatcgg gtttacgctt aatgaccaat ttcggcagcg cgcgcggttc acggcttaat
      181 tgcaggtgcg tctgctccat atggttgctg tacaggtgcg tgtcgccgcc ggtccagaca
      241 aaatcgccga cgtccaggtc gcactgttgc gccatcatat gcaccagtaa cgcgtagctg
      301 gcaatgttga acggcagacc gaggaacaca tcgcaggagc gctgataaag ctgacaggag
      361 agttttccat ctgcgacata aaactggaaa aaggcgtgac acggcgccag cgccatctta
      421 tccagctcgc cgacgttcca cgcagaaacg ataatacgac gagagtccgg gtcgttttta
      481 agctggctca agaccgtggc gatctgatcg atatggcggc catccggtgt tggccatgca
      541 cgccactgct taccataaac cgggcctaaa tcgccgttct catcggccca ttcgtcccag
      601 atggtgacat tattttcgtg taggtaagcg atgttggtat cgccctgcaa aaaccatagc
      661 agttcgtgaa taattgaacg taaatggcag cgtttcgtcg tcaccagagg aaagccttcc
      721 agcaggttaa aacgcatctg atggccaaaa atggaaagcg tgccggtgcc ggtacggtcg
      781 tttttctgtg tgccttcatc cagcactttt tgtatcagtt ctaaatactg tttcatggtt
      841 cctcaggaaa cgtgttgctg cgggcggcgg cgatatgccc aaaccatcat gatcgcgcca
      901 gcgataatca tcgggataga gagaatctgc cccatgctga tgtactgtac ccacgcgccg
      961 gtaaattgcg cgtccggctg gcggaagaat tcaacaatga tacgaaacgc gccatagcca
     1021 atcaggaata atccggagac tgcgcccatc ggacgcggtt tgcgaataaa gagattaagg
     1081 atgataaaca gcaccacgcc ttctaatgcc agctcataca actgggaagg gtggcgtggc
     1141 aatacgccgt aggtatcaaa aataggctgc cattgcggat gtgacggcag cagcgcaata
     1201 tcttccgcgc gtgagccagg aaagagcatg gcaaaccgga agtcaggatc gacgcgcccc
     1261 cacaattcac cgttgataaa gttgcccaga cgcccggcgc ccaggccgaa cggaattaac
     1321 ggcgcaataa aatcagacac ctgaaagaac gagcgcttcg tgcgcctggc gaagataatc
     1381 atcaccagta tcacgccgat aagcccgccg tggaaggaca tgccgccgtc ccagacgcgg
     1441 aataaataga gcgggttatc cagaaacaga gggaagttat aaaacaggac atagccaata
     1501 cgtcccccca ggaagacccc caggaaacct gcatagagta aattttcaac ttcgtttttg
     1561 gtccaaccgc ttcccggacg gttagcgcga cgcaccgcca accacatcgc gaaaacgaac
     1621 cccaccagat acatcaagcc ataccagtga agcgcgacgg gcccaattga gaaaatgacc
     1681 ggatcaaagt ccggaaaatg cagatagcta ctggtcatct gtcaccacaa tttcttgtta
     1741 tttcgctgaa gagatagcga ttgataagcg cgcctgcgcg ttgcagacgc tccaaaggtg
     1801 cgaataatag cacaagggtt aaaagcgaga tgccgattac cgttaaaaga tatgtatacg
     1861 cattgtcttt catcttgcag gcgtgttgtc tgcgccgtga atccacagtc actttttccc
     1921 gctccagtcg ttacaaccct ccgcgaatca atccccccat cccgcggcgc tccataaacg
     1981 ccgccacctg atgacgcact tcggtcgcca tctgcgcctc aaggctgcgt ctggcaaggg
     2041 tttgcgcgtc ttcaaaatcg atatgccgca gcagatattt cacacgcgct accgaacggc
     2101 cattcatcga aagatggcga tatcccagac cgataagaat cgccacgcac atcggatcgc
     2161 ccgccatctc gccgcacaag cgaagatcga gaccatgttt ttcggcttcc tgcgcgatca
     2221 tggacagtgc gcgcagcata gccggatgca aactgtcata aatactggcc acgcgggtat
     2281 tgttgcgatc taccgccagg atatattgcg ttaaatcgtt ggtgccgacc gagataaagt
     2341 cgatccggtt agccagatgc ggcagcataa ataccattga tggtacttcc agcataatgc
     2401 cgatacgcgg tttcgggatc gcatagccga tcatctcctc gacctcgcgc ccggcgcgtt
     2461 cgatcagacg ccgcgcttca tcgacttcat caatactggt gaccatcggc aacaaaatgc
     2521 tgaggttgcc agtcgccgca ttggcacgca gcatcgcgcg gacctggatc aaaaagatct
     2581 ccggctgatc cagcgtaatg cggatcccgc gccagcccag acacgggttc tcctcgctga
     2641 tcggcatata gggcagttgc ttatccgctc ccacatccag ggtccgcagc gtcaccggtt
     2701 tatcgttaaa catttgcagc atcccttgat actgcgccac ctgctcttct tccgagggaa
     2761 acccgctttg cagcatgaag ggaatttcag tacggtacag gccgataccg tcgatccgac
     2821 tgcctaactt ttcctcatgc tcggggctga gcccggcatt cagcatcact ttgatacgct
     2881 cgccgctttt cagttgggcg ggaagattga cgtcgtcctc cgccagacga ctgagttcta
     2941 tctcttcact aatgagccgc tgatattcct gaataagcac gggttcagga tcgaccagta
     3001 attcaccgcg atagccatcc accaccaacg tacggcgatg tagcaccgaa ggctggatat
     3061 ccgcgcccat gacggtgggg ataccgagcg cgcgcaccat aatcgccgca tgcgagtttg
     3121 ccgcgccgtc gcgcaccaca acgcccgcca gcctgtcctg cggcagctcc gccagggtgg
     3181 tcgccgacag ctcatccgcg accagaataa aacgttccgg ccaggcgttt ggcccctgaa
     3241 ctgaatcatc aagatggaat aacagccgct gccccagcgt gcgtaagtct cccgcacgtt
     3301 ctttgaggta gttatcggtt agcgccgcaa attgctcggc aaatttttcg atgatttttt
     3361 taacggccca ctccgcaaca gcgcctttgt cgacctcggc gaagagttcg cgacgcagtc
     3421 tggcgtctga aagcaggtgt gagtacagat cgaaaatggc tgccgtctct ttttgtgcgc
     3481 cggcggcaaa gcgtttgctg tatcgtcgga attcgttcgc cgcctcttcc agcgcgccgg
     3541 tcaatcgttc gcgttcaaga gaggtatcca gcgtagacgc ttcgtaaacc tgttccatca
     3601 gcggcatggt cgcgtcttgc cagcccgttg cgatagccac gcccggcgcc gcaggaagcg
     3661 cgcgaattcg cgtctgccgg tattgcccga atagcgctgt gacctgcgac tgtgacagga
     3721 tagccgccat ctgcgtagcg agcgtgacga ggaaagactc ttcgctttca tcgtactggc
     3781 gcaattcgcg ctgctgcacg accagcacgc cgagaagttg gcgacgctga atgatcggca
     3841 caccgagaaa cgcgcgaaaa cgctcctctt ttaccgaagg aatgtattta aagctgggat
     3901 gtttttgcgc atcggcaagg ttaatgggtt ccgccagcct gcccaccaga ccgacgatcc
     3961 cctcatcaaa cgcaagcgca acggttcgac cacgcggttt tttcaacccc cgcgtcgcca
     4021 tcaggtaata acagcgtcgg tcatgatcgg ccaggtaaac cgagcaaacc tctgtatcca
     4081 tcgcaagaca gatatccgtg accagaatat tcagcgcctc gttcagacgc ggcgcactgg
     4141 ccactttttc gactatttcg cgcaggcgag tgagcataat ttgcgtggct taacctcttt
     4201 tacgtcgata agcaggcgcg ctttgtagct tagggggatt atcctgaagc gccatgacaa
     4261 cacttgcaaa ctctttcatt accctgcggt agacatcgcg tttaaatgac accacttgtc
     4321 gaaccggata ccagtaactt acccagcgcc agccgtcaaa ctccggcgta ctgctggttt
     4381 gcatattgat ttcggcgtcg gcgctcatta actgcaaaag aaaccacttt tgtttctggc
     4441 cgatacatac cggctttgtg tcccaacgca ccaaacgttt tggtaacttg taacgcaacc
     4501 agttgcgagt agaagcaagg atccgcacat ctttacggct taacccaact tcttcaaaca
     4561 gttcccggta catcgcctgt tctgccgact cccctggatt tatcccgccc tgcgggaact
     4621 gccaggagtg ctgaccaaat cgccgggccc acatcacctg cccctgacga ttacaaatta
     4681 cgatacctac atttgggcgg tagccatcgt catcaatcac cggactacct caacataaac
     4741 cttatatatg aacgattgtt tcatactcca gtgaggcggt aaaccactct gtaatagtga
     4801 cacagcctaa taacaattga ataactcaca gtaaatagcc gagttataaa cagatgatga
     4861 cgcccttgcg ccattttatt caccttttct gtggatatag ttgtgaagaa gtatggaatt
     4921 accacgggaa aacccagaac agtctgaatt cctcatactg aaaacagtaa aaatagtgcc
     4981 ttatattcat tgtgttatag acaaatctta catgccacct tcataaagcg tgaccagcat
     5041 cacatctaag atccttatgc tgatgaaaga tcaaccagcg tcggttttat ccacagattg
     5101 tgccaataac ttacgcacta tttgtctgaa ttttcgattt tcgtcgcacg tcaaggctgt
     5161 aaatggaaac agtagtggtg gttttacaca gttatcccaa ctttctgtgg ataacatagt
     5221 gtaagatcct gtttattgtt agtgaccaga attggaaaac ccgcttcagc gttgcgcaac
     5281 acgaagaaac aacacaaaaa aggcaataaa aatcagtcta ttgaatataa gacacagaaa
     5341 aagataaact ctgcccatac ggtataaaaa cactgctcat tttttgacct aaggtaattg
     5401 tcatgtccgc tctttgtccg ctactgactc cgcctgcttc ggaagcattg ctgttagccc
     5461 aggcgcggca gctttccggc tatacgttag gcgagctggc ggtgatggcc ggcattacca
     5521 cgcctaaaga tttgaagcga gacaaaggct ggatcggcgt cttgctggag atctggctcg
     5581 gcgccagcgc cgggagcaag ccggagcagg atttcgccgc gttaggcgta gaactgaaaa
     5641 ctatcccggt ggatagtctg ggtcgtcctc tggaaacaac ctttgtttgc gtggcgccgt
     5701 taaccggtaa cagcggcgtg acctgggaga caagtcacgt acggcataaa ttgaagcgcg
     5761 tgctatgggt gccggtcgaa ggcgatcgca gcataccgtt agccgaacgc cgcgtaggtt
     5821 cgccgctact ctggagtccg agtgaagaag aggacaggca gctacgcctc gactgggaag
     5881 agctgatgga catgatagtg ctgggccagg tggaacgcat taccgcccgc catggcgaag
     5941 tcttgcaact gcgacccaaa gccgccaatg ccagggcgct caccgaggct atcggcgcgc
     6001 gcggggaacc tattttgacg ctaccgcgtg gattttatct gaaaaaaaat tttacgcagg
     6061 cgctgctggc tcgccatttt ttattgcaga atccgtaacg tccattacac gcaaatgcgc
     6121 ctccgctatg gctacgcgtc gggccgacgc cggataaacg taagcgtatt gtcgccgcta
     6181 ttttacaccg ttcctggttg cgcaaattca gcctgggctt tcgcccgtca ctcgacgggc
     6241 ctataattac cgcttctttt tttggcagga ctttgttcga tgttatttgc atggataacc
     6301 gatcctaatg cctggctggc gctcggtacg ctgacgctgc tggagattgt acttgggatc
     6361 gacaacatta tttttctttc tctggtggta gcaaaacttc ctacggcgca acggaaccac
     6421 gcacggcggc ttgggttggc ggcggcgatg gttatgcgcc tggcgctgct ggcgtcaatc
     6481 gcctgggtca ctcggctgac taatccgctg tttgagcttt tcggcgaagc gatttccgcc
     6541 cgcgatctca ttctgttact gggtgggtta tttttaatct ggaaagccag caaggagatc
     6601 catgagtcca tcgaaggcga agaagaaggg ttaaaaaccc gggtttcttc tttcctgggc
     6661 gcaatagtgc agattatgct gctggatatt attttcagcc ttgattcagt tatcacagcg
     6721 gttggcctct ccgatcatct gtttattatg atggcggcag tcgttattgc cgtgggtgtc
     6781 atgatgtttg cggcacggcc catcggcgag tttgtcgatc gtcatccgtc ggtaaaaatg
     6841 ctggcgctct cctttctgat cctggttggc tttaccctga ttctggaaag tttcgacgtt
     6901 cacgttccga aagggtatat ctatttcgcc atgttcttct ctatcgcagt agagagcctg
     6961 aacctgttgc gtaataaaaa gaatccgctg taatcctgtc tcgctccccc gccgggggag
     7021 cgaatactca ctttatttcc tttcttctca cagattaaga ttttgctgct tccgacatgc
     7081 agagctgcgc gttattacta gactattatc agacatatga ttaacagact attatcagat
     7141 gcaggctacg tgaggaaaaa cggatgaaaa agtgggcagt tgtaatttcc gcagtagggt
     7201 tggcttttgc ggtatccgga tgcagcagcg attatgtaat ggcgacgaaa gatggtcgta
     7261 tgatcctgac cgatggaaaa ccgcaagttg acgatgatac cggtctggtc agctataccg
     7321 atacacaggg aaacgagatg caaatcaacc gtgacgaagt gtctcaaatc atcgaacgtt
     7381 aagcggtggc ctgtgatcga ggtcagcgtt ctgcaagcct tcaggctgcg tcccgtaacg
     7441 gtgcgtggcg accacgcccg gtaacaatta cgccgtgcag cctgcaattt tactttccct
     7501 tttgccttcc ctctgccatt tttattgtcc tttgtcggga atttctgact tcataataaa
     7561 aaggaaacgg ctatgcacta tcaccgtata ccccacagct cgctcgaagt aagtacgcta
     7621 gggctgggca caatgacatt tggtgaacaa aacagcgaag ccgacgctca cgcacagctc
     7681 gactatacca tcgcaaatgg cattaacctt atcgacgccg ccgagatgta tccggtaccg
     7741 ccgcgcccgg aaacacaagg gctgacggag tcctatatcg gtaactggct cgccaaacgc
     7801 ggcaaccgtg aaaaactgat catcgccagc aaagttagcg gaccggcacg taataatgat
     7861 caaggcatcc ggcctcatca ggcgctggat cgtaaaaata ttcgcgaagc gctacacgac
     7921 agtttgaccc ggttgcagac cgactatctg gatttgtatc aggtgcactg gccgcagcgc
     7981 cccactaact gcttcggtaa actcggctat aactgggcgg actccatgcc agtagtaagt
     8041 ctgctggaga cgttagacgc gctaagtgag tttcagcgag cgggtaagat tcgttatatt
     8101 ggcgtttcaa atgagacagc gtttggcgtt atgcgctatc tgcatctggc ggaaaaacat
     8161 gacctgccgc gtattgtcac tatccagaac ccctatagcc tgttaaaccg cagctacgag
     8221 gtcggactgg cggaagtcag ccagtatgaa ggtgttgaat tgctcgccta ttcctgtctg
     8281 gcgtttggca cattaaccgg taaatacctg aacggggcca aacccgcagg cgcgcggaat
     8341 accttgttca gccgcttcac acgttacagc ggcgaacagg cacaaaaagc cgttgccgcc
     8401 tacgtcgata tcgcgaagcg tcacaatctt gatccggcgc agatggcgct ggcctttgtt
     8461 cgccgccagc cgtttgtcgc cagtacgtta ctgggcgcaa ccacgatggc gcagctcaag
     8521 acgaatgtgg aaagtctgca tctgacgtta agcgaagagg tcctggcgga gatagaggcg
     8581 gtgcatcagg tttataccta cccggcgccg tgatggtcag tgcccggtgg cgctacgctt
     8641 ccgggcttac agagacaatg taagccggat aacgcgcact cgccgcccgg catattcact
     8701 cagtatgatg cctgccggcg ctgccagatc cacagcgccg cgatcgccag cgcgaacagc
     8761 acgccaaagc cgatacctat cgccactgcc ggaacgccaa ccagcaccgc cagcgagtac
     8821 agtcccagca ttaatagcat ggcgctattc tcgcccagat tttgtacggc aatggcattc
     8881 ccggcaccaa cgctcttctt accgcgctcc tggagcaaag cgttgagcgg caccacaaaa
     8941 aagccgccca gcatacctat caacaacaac aaggcataag caggcagcaa tgcgtgctgt
     9001 aatgagaaga tcgcaaccac aacgccaatc aaaatcccag cgggcataca gcgcgatacg
     9061 gtctccagcg tcaccagttt tgccgccgca cccgcgccga ccacaatgcc taccgccacc
     9121 atggcgttca ggtaagtcgg cgtggcgtta tccgtaatgc ccagcgccac cggcacccac
     9181 agcaccagca gaaaacgcag cgtcacgcct gcgccccaga atagcccggt ccccaccagc
     9241 gaaaaacgcg tttcaccgtt acgccaaagg acaacgcaag cgcagaagaa gctacgcgtc
     9301 atcgccgaca accgccagga ttgtcctgga cgcgccgcca caagcttcgg gataaacagg
     9361 ttcgccgcca ctgcgccagc gtaggccaac gcgcaggcaa ccagcgcggc gatgacatgc
     9421 cagtcggcca atacgccgcc cgcgacggaa ccgagcaaaa tcgccgcaat cgtagaggct
     9481 tccatcaggc cattggcttt caccagctta tcgcccgtcg tcagttcgcc cagaataccg
     9541 tatttcgccg gagaataagc cgccgcgcca atcccgacca acgtataacc gacaaaagga
     9601 tttacgccga ggcagatacc tgccgctccc gccagtttaa gaccattggc gaccatcatc
     9661 acccggcctt tggcaaagct gtccgctatc tggccgacaa acggcgcaaa aagaatgtaa
     9721 gcgcccacaa acaccatttg caaaacaggc tggctccagt ccgggtaaaa ctgagctttc
     9781 agcagtgcca gcgtcgcgaa cagcagcgca ttatcgccaa aagccgagag aaactgcgcg
     9841 acaattaccg acagcatccc tttcgaccag atggaggtgt tagtacgtac tgactcactc
     9901 atgatgttgt tccggcgcat ccacccaact tttcagcgtc acaaaatcgg gtttcccgct
     9961 gccaagcaag ggaagctgtt tcagataacg gatatcacgc gggacggcaa gttccggaat
    10021 accgtgttca cgggcatagt gctgtaactt ttctcgggtg agttcgctgt cagtcgtaaa
    10081 cagtaccagc gcttcacctt tgctggcatc gcttttaatg gcggtagcgt gcattttctc
    10141 cgccgaaacg ccaagcgcca gttgctcgac catctccagc gagaccattt cgccagcaat
    10201 tttcgcaaag cgtttcgcgc gcccctgaat ctgcacaaaa ccattttcat cgaagcgtac
    10261 aatatcgccc gtgtcgtacc acccgcgctc ggtttcgcct ctggcgtttt ccgccgacgg
    10321 cacctccagc acgcccggtt tttccacgcg cagatagcca ttcatgatat tcggcccttt
    10381 cagctgtagc cgaccgccgt tttcaatacc gggcaccgcc agcagacgcg cgtccatgcc
    10441 aggcagaatg cggccaacag tgccaggctt agccgccatc ggcacgttaa tcgagactac
    10501 tggcgcgcat tccgttaccc cgtagccctc aagaatgcgc agaccgaatt tatcctgcca
    10561 cagttgtttg gtgctctcct gaagtttttc cgcaccggcc accacatagc gcaggcgata
    10621 aaaatcatac ggattggcaa agcgcgcata gttgccgagg aaggttgatg taccaaacag
    10681 cacggtacag ttacggtcat agaccagttc cggcacaatg cggtagtgca gcggacttgg
    10741 ataaagaaac acttccgcgc cggtcaacaa cggcgtaaac aggcccaccg tcaaaccgaa
    10801 cgagtgaaag agcggcagcg ccgacataaa acgatcattg gcggtgaaat ccgcaatcgt
    10861 ttttatctgc tcgacgttcg ccagaatact tttatggctg tgcaccaccc ctttcgggtg
    10921 cccttccgag ccggaggtaa aaagaataat cgccgcgtct tccggctgct gttttacctg
    10981 cgccagtcgc ggcgccagga ggtgggcaaa aatccacagc ttgtcggcgg gtgtgacgtc
    11041 cgcttttaaa tcttccaggt aaacccagcg aacctgcgtt agctgctccg gcaggtgcca
    11101 caatttacct ttatcgagga actggcggga ggtaaaaatc gttttaattt ccgccgcggt
    11161 aatcgcgctg gtcagccctt ttacccccgc cgtgtagttc atcatggccg gaatgcggcg
    11221 acgagaaacc gcgccgaaaa tcaccgccgc gctgatggcg gcattcggca gcattaaacc
    11281 gattttctcg ccctcaacgc tgtacttttc cagaatccgg ccaacaaaaa gcgtcttggt
    11341 cagtaactta cgatacgtat ccggcgtaaa gttaatgtcc tcaatacagt ttttacccgc
    11401 gccgtaacga tattgcgccg ccagcaacga ttcgtataac gtctcgcgcg ggcgcactgc
    11461 catacgcgct tccatcatga tctggtgcag catctcaccc gctatcttac gtctgtcgcg
    11521 cgcgcgcggc gcttccggca tcggtatttg cgtcggcggt aaaatatgaa gctgaatgcg
    11581 ggggaataag cgccgtttaa ccagaccttt caggcgactg aaaggggtaa gctccgcgcc
    11641 gtcaatgcgg agcggaatga cggttgcgcc cgattttgcc gccacaaagc ctgcgccgtc
    11701 ataaattttc atcagcgagc cggtcacgga aatccgccct tccgggaaaa tcaccactgg
    11761 acgcccctgc tccaccagac gcaccaggtg tttaatggac atgggtttag tgggatcgag
    11821 cggtacaaaa tcgatcagcg gcgttaacca gcgcatatac cattgctggc tgatggaggt
    11881 atataccgca aagacaggcc gtaccggcaa aaacagcgcc agtagcatac catcgataaa
    11941 tgaaacgtga ttgggggcaa ttaagacccg gttcccctgt agcgcccgga catcgccagt
    12001 gacgcgcaca cgataaagca cgcgaaacag gttacggaaa aatccaaaca gcatttcaac
    12061 tccctttggc cgacaattcg ctaaaacatg aattgtggca gattacacga gttgcgtaac
    12121 aggagcgata gcaaaatagg tt
//
LOCUS       DAJVKX010000132        12136 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.132, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000132 DAJVKX010000000
VERSION     DAJVKX010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.132"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..206)
                     /locus_tag="OPY25_003663"
     CDS             complement(<1..206)
                     /locus_tag="OPY25_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0929167.1"
                     /translation="MSTKFYTLLTDIGAAKLASAAALGVPLKITHMAVGDGGGVLPTP
                     DAKQTALVNEKRRAALNMLYIDPQ"
     gene            complement(203..808)
                     /locus_tag="OPY25_003664"
     CDS             complement(203..808)
                     /locus_tag="OPY25_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HCS0929168.1"
                     /translation="MNSLLPPGSTPLERRLAQTCSGISDLQVPLRDLWNPATCPVSFL
                     PYLAWAFSVDRWDEGWTESVKRQVVKDAFYIHQHKGTTSAVRRVVEPFGFLIHIIEWW
                     QTGEAPGTFRLDIGVQDQGITEDTYLELERLISDAKPCSRHMIGMSINLQTSGPHWVG
                     AASYLGEEITIYPYINETIISGGTAHEGGAVHVIDTMRVNP"
     gene            complement(801..1709)
                     /locus_tag="OPY25_003665"
     CDS             complement(801..1709)
                     /locus_tag="OPY25_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HCS0929169.1"
                     /translation="MAVIDLSQLPAPQIVDVPDFDTLLAERKAEFVALHPKDEQEAVS
                     RTLELESEPVTKLLQENAYRELLLRQRINEAAQAVMAAYAIGSDLDQLAANYNVKRLT
                     VTPADNDAVPPVAAVMESDEALRLRVPAAFEGLSVAGPTAAYEFHARSADGRVADASA
                     TSPAPAEVVLTVLSREGDGTAEKDLLDVVEKALNSENVRPVADRLTVRSAEIIPYRVE
                     ATIFLYPGPEAEPVMAAAKASLQKYIASQTRLGRDIRRSAIFAALHVEGVQRVELASP
                     LADMVLNKTQAASCTQWSVTNGGTDE"
     gene            complement(1696..2055)
                     /locus_tag="OPY25_003666"
     CDS             complement(1696..2055)
                     /locus_tag="OPY25_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013098787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HCS0929170.1"
                     /translation="MTLYSGMNNTSGKVITDIDHLRQSVRDILLTPQGSRIARREYGS
                     LLSSLIDQPQNPALRLQVMSAVYVALSRWEPRLTLDSITINSHFDGSMVVELTGRRNN
                     GVPVSLSVSTGAENGSD"
     gene            complement(2052..2630)
                     /locus_tag="OPY25_003667"
     CDS             complement(2052..2630)
                     /locus_tag="OPY25_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HCS0929171.1"
                     /translation="MNAQLTEIMRLITNLIRTGVVTEVDREHWLCRVKTGDLETNWIN
                     WLTLRAGNARTWWKPSEGEQVVLLSLGGNLETAFALPAVYSNQFAPPSTSADACVTEH
                     PDGGWFEYEPATGRWYVRGIKSMVIEAADNITMKTSEFVLEADRTRINSEVVINGGVT
                     QGGGAMSSNGIVVDAHQHTGVLKGGDTTGGPV"
     gene            complement(2699..3145)
                     /locus_tag="OPY25_003668"
     CDS             complement(2699..3145)
                     /locus_tag="OPY25_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HCS0929172.1"
                     /translation="MAELQKVDDWLSALLANLEPATRSRMMRQLAQELRRTQQQNIRM
                     QRNPDGSSYEPRRVTARSKKGRIKRQMFAKLRTTKYLKTAASADSASVQFEGKVQRIA
                     RVHHYGLRDRVSRKGPEVRYAERRLLGVNDDVEAMTRDMILQWLAG"
     gene            complement(3138..3569)
                     /locus_tag="OPY25_003669"
     CDS             complement(3138..3569)
                     /locus_tag="OPY25_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0929173.1"
                     /translation="MNKPQSLRHALNKAVPYVRNNPDKLHLFVDNGSLVATGASSMSW
                     EYRYTLNVVIEDFSGDQNLLMAPVLLWLRDNQPDAINNPALREKLFTFDVDILRNDVC
                     DISLNLQLTERVLVSTDGSVSSVEAVAEPDEPEEMWTVKRG"
     gene            complement(3665..4093)
                     /locus_tag="OPY25_003670"
     CDS             complement(3665..4093)
                     /locus_tag="OPY25_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HCS0929174.1"
                     /translation="MMRALAVVLALALAALGWQSWRLNNASHTIETQGAALKSKTQEL
                     TKKNSQLIGLSILTETNSREQTRLYAAAEQTTALLRSRQRRIEELKSENEDLRRWADT
                     PLPADIIRLRDRPALAGGAAYREWLSQSDAVPPGKVSAAQ"
     gene            complement(4090..4467)
                     /locus_tag="OPY25_003671"
     CDS             complement(4090..4467)
                     /locus_tag="OPY25_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCS0929175.1"
                     /translation="MKKKVMSVFFQLAWAALLVISLLYPRSGAPVLVGASVQVSCFLA
                     WLLAALCAVGWFAGDRARDEVRAALIKFRAHPVKPVRTWAIRLLIVLCLAFSGWVITL
                     VFYLLTLVLYQIARSQLHEPMAA"
     gene            complement(4472..4981)
                     /locus_tag="OPY25_003672"
     CDS             complement(4472..4981)
                     /locus_tag="OPY25_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HCS0929176.1"
                     /translation="MNTSIVKCCLVGAVLAIAATLPGFQSLHTSVEGLKLIADYEGCR
                     LQPYQCSAGVWTDGIGNTSGVVPGKTITERQAAQGLITNVLRVERALEKCVVQPMPQK
                     VYDAVVSFAFNVGTGNACSSTLVKLLNQRRWADACHQLPRWVYVKGVFNQGLDNRRAR
                     EMAWCLKGA"
     gene            complement(4962..5177)
                     /locus_tag="OPY25_003673"
     CDS             complement(4962..5177)
                     /locus_tag="OPY25_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929177.1"
                     /translation="MTLERISAFITYCIAVLLAWLGDLSLKDASTVGGVLIGVLMLAI
                     NWYYKHQSFKLLRGGKISRGEYEYFNR"
     gene            complement(5181..5384)
                     /locus_tag="OPY25_003674"
     CDS             complement(5181..5384)
                     /locus_tag="OPY25_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HCS0929178.1"
                     /translation="MKVRAHQYDTVDALCWRHYGRTQGVTEQVLQANPGLAEYGPFLP
                     HGLQVELPDITASTTAQTVQLWD"
     gene            complement(5384..5848)
                     /locus_tag="OPY25_003675"
     CDS             complement(5384..5848)
                     /locus_tag="OPY25_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HCS0929179.1"
                     /translation="MKFVAPEQAPEQAEVIKNTPFWPDVNLSEFRSVMRTDGTVTQPR
                     LKQVVLTAISEVNAELYDFRNRQQMLGWRTLAEVPAEMLDGKSERIRHYHNAVFCWAR
                     AVLNERYQDYDATASGVKRGEELAEASGDLWRDARWAISRVQDAPHCTVELI"
     gene            complement(5942..6592)
                     /locus_tag="OPY25_003676"
     CDS             complement(5942..6592)
                     /locus_tag="OPY25_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HCS0929180.1"
                     /translation="MSLSPARQHRLRIQAEQAAREGGSVRHASGYDLMLLQLAEDRRR
                     LKGVQSTVKKAEIKVELLPKYSAWAEGVLAAGGAQQDDVLMYVMLWRIDAGDYAGALE
                     IGRHALRHGWVMPLGNRNVQTVLAEEMADAAQSALLAAAGFDADPLLQTLDLTTDLDM
                     PDQSRARLHKAIGAVLSESNPASALNHLNHALQLDPRCGVKKEKQQLERRLRNDSR"
     gene            complement(6596..7660)
                     /locus_tag="OPY25_003677"
     CDS             complement(6596..7660)
                     /locus_tag="OPY25_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HCS0929181.1"
                     /translation="MKKKTRFAFNAYLQQLARLNGVDVEELSSKFTVEPSVQQTLEDH
                     IQQSAAFLTLINITPVTEQSGQLLGLGVGSTIAGTTDTTTKEREPTDPTLMEDVEYKC
                     EQTNFDTVLTYAKLDLWAKFQDFQVRIRNAIVKRQALDRIMIGFNGVKRAKTSNRAEN
                     PLLQDVNKGWLQKIREDAPDHVMGSKTAEDGTTTAEPVKVGPGGKYVNLDAVVMDTVN
                     ELIDVEYQDDDELVVVCGRELLSDKYFPLVNKEQDNSEKIAADLIISQKRMGGLQAVR
                     APFFPANALLITRLDNLSIYWQEDTRRRSVIDNPKRDRIENFESVNEAYVVEDYRCAA
                     LVENIEIGDFSAPAAPESGE"
     gene            complement(7677..8510)
                     /locus_tag="OPY25_003678"
     CDS             complement(7677..8510)
                     /locus_tag="OPY25_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HCS0929182.1"
                     /translation="MTVKAKRFRIGVEGATTDGREIQREWLVQMAASYNPTVYTALIN
                     LEHIKSYLPESTFNRYGRVTGLVAEEIQDGPLAGKMALYADIEPTDALVELVKKGQKL
                     FTSMEVSTKFADTGKAYLVGLGATDDPASLGTEMLAFSASAAHNPLANRKQNPENLFS
                     EAVETLIELEEAQDEKPSLFASVTALFTKKEQTDDARFSDVHKAVELVATEQQNLSER
                     TDKSLAENGERLSALESSLQEQQTAFAELQQQLSREDSRKDYRQRAPGGDAPAGTLTN
                     C"
     gene            8653..10419
                     /locus_tag="OPY25_003679"
     CDS             8653..10419
                     /locus_tag="OPY25_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HCS0929183.1"
                     /translation="MNTTLTPADLDPRRQAMLLYFQGYRVARIAEMLGEKVATVHSWK
                     KRDKWGDYGPLDQMQLTTAARYCQLIMKEQKEGKDFKEIDLLARQSERHARIGKFNDG
                     GNEADLNPKVANRNKGPRRQPEKNVFSDEQIEKLEEVFHASMFDYQRHWFEAGKINRI
                     RNLLKSRQIGATFYFAREALIDALLTGRNQIFLSASKAQAHVFKQYIIDFAKEVEVEL
                     KGDPMVLPNGAALYFLGTNARTAQSYHGNLYLDEYFWIPKFQELRKVASGMAIHKKWR
                     QTYFSTPSSLTHSAYPFWSGALFNRGRAKADKVDIDLTHSNLARGLLCPDGQYRQIVT
                     VEDAVRGGCNLFDLDQLRMEYSPDEYQNLLMCEFIDDLASVFPLSELQACMVDSWEVW
                     TDFQALALRPFGWREVWIGYDPAKGTQNGDSAGCVVIAPPTVPGGKFRILERHQWRGM
                     DFRAQADAIKKLTQQYNVTYIGIDSTGVGHGVYLNVKDFFPAVREFVYNPNVKNALVL
                     KAYDIISHRRLEFDAGHTDIAQSFMAIRRATTASGNRPTYEASRSEEASHADLAWATM
                     HALFNEPLQGEAANTSNIVEIF"
     gene            10419..11462
                     /locus_tag="OPY25_003680"
     CDS             10419..11462
                     /locus_tag="OPY25_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCS0929184.1"
                     /translation="MSEHDALTSTAPVQEAEQQKNTTHAEAFSFGDPIPVLDRRELLD
                     YVECVQMDRWYEPPVSFDGLARTYRAAVHHSSPIAVKRDILSSTYIPHRLLSQQAFAR
                     FVQDYLVFGNAYLEKRTNRLGGVLSLEPALAKYTRRGLDLDTYWFVQYDLTTQPYEFT
                     QGNIFHLMEPDINQEIYGLPGYLSAIPSTLLNESATLFRRKYYINGSHAGFIMYMTDA
                     AQNQEDVNNIRQAMKSAKGPGNFRNLFMYSPNGKKDGIQIIPLSEVAAKDEFLNIKNV
                     SRDDMMAAHRVPPQMMGIIPNNTGGFGDVEKASRVFVRNELIPLQERIKELNEWLGDE
                     VIRFAKYTLDDIS"
     gene            complement(11511..>12136)
                     /locus_tag="OPY25_003681"
     CDS             complement(11511..>12136)
                     /locus_tag="OPY25_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929185.1"
                     /translation="KNTPYSDAIGAGFTKYETIHNGMTATFNKKSVVLEPIADPFGEV
                     LEFERVVFDQISFSIQTLSNKICLLTFYNPPKTVKPFIDFLSQAEGLNVAYGNLTVDL
                     KAFMRVIRENFGVKVFGISKVKVSNLPVTEKTRACLELNSSGDALHDLKIFVGDSEFK
                     LDKIKAGGFYLDSKISFELTSGASAVVPDEHFSIFNDAISCMEIDKF"
BASE COUNT         2670 a         3593 c         3186 g         2687 t
ORIGIN      
        1 ttctgcgggt cgatataaag catattcagc gcagcccggc gtttctcatt taccagtgcc
       61 gtctgctttg cgtccggcgt tggcaatact ccgccgccat cgcccaccgc catatgggta
      121 atttttagcg gcacaccgag cgcggcggcg ctggcaagtt ttgccgcgcc aatatccgtc
      181 agcagggtat aaaattttgt gctcatggat tcactctcat tgtgtcaata acatggaccg
      241 ccccgccttc atgcgcggtg ccaccggaaa taatcgtttc gttgatatac ggatagatcg
      301 tgatttcttc gccaagatag ctggcggctc ccacccaatg cgggccgctg gtctgcagat
      361 tgatggacat gccgatcatg tggcggctac atggtttggc atcgcttatc agtcgctcaa
      421 gttccagata ggtatcttca gtgatgccct ggtcctgcac gccgatatcc aggcgaaacg
      481 tgcccggtgc ctctccggtc tgccaccact caataatgtg gatcaaaaag ccgaacggct
      541 ccaccacccg ccgcacggca ctggtggtcc ctttatgctg atgaatataa aaagcatcct
      601 tcaccacctg gcgcttgacg ctttctgtcc agccctcgtc ccagcgatcc acagagaacg
      661 cccaggcgag ataaggcagg aaactgaccg gacaggttgc cggattccac aagtcacgaa
      721 gcggcacctg cagatcagaa atcccgctgc aggtttgcgc caatcggcgc tccagtggtg
      781 ttgaacccgg tggcagcaga ctattcatcc gttcctccgt tggttacgct ccactgcgta
      841 catgatgccg cctgtgtttt gttcaggacc atatccgcca gaggagaagc cagctccaca
      901 cgctgcacac cctcaacatg cagggcggca aagatggcgc tacggcgaat atcccgacca
      961 agacgcgtct gactggcgat gtacttctgc aggctggctt ttgccgctgc cattaccggc
     1021 tctgcttccg gtcccggata gagaaaaata gtggcttcca cccggtacgg gatgatttct
     1081 gcgctgcgaa ccgtaagacg gtcagccacc gggcggacgt tctcactgtt cagagctttt
     1141 tccaccacgt ccagcaggtc tttttctgct gttccatcgc cttcgcggct caggacagtc
     1201 agcaccacct ctgcaggtgc cggactggtt gcactggcat ccgccacccg accgtcggcg
     1261 cttcgggcat gaaattcata agcggcagtt ggccccgcaa ccgaaagccc ttcaaaagcc
     1321 gcaggcacac gcaggcgtaa cgcttcatca ctttccatca cagccgcgac gggcggcaca
     1381 gcgtcattat cagcaggcgt caccgtcagg cgtttcacgt tgtaattggc agcgagctgg
     1441 tccagatcgc tccctatggc ataagccgcc atcaccgcct gcgcggcttc gttaatgcgc
     1501 tggcgcagaa gcaactcacg ataagcgttc tcctgcaaca atttggtgac gggttcagat
     1561 tccagttcca gtgtgcggct cactgcttcc tgctcatctt tcggatgaag cgccacaaat
     1621 tctgccttgc gttcggcaag caacgtatca aagtccggca catccacaat ctgcggcgca
     1681 ggcaactgcg aaaggtcaat cactgccatt ctctgctcct gttgatacgg aaagggaaac
     1741 aggtacaccg ttattacgcc gcccggtcag ctccaccacc attgaaccgt caaaatggct
     1801 gttgatggtg atggaatcca gcgtcagccg tggctcccag cgactcagcg ccacatacac
     1861 tgccgacatg acctgcaggc gtaatgccgg attttgtggc tggtctatta gcgacgacag
     1921 cagggaacca tattcacgac gagcaatgcg gctaccctgc ggcgtcagca gaatgtcccg
     1981 caccgactgg cgcagatggt caatatcagt aatgactttg ccgctggtat tgttcatccc
     2041 gctataaagc gtcataccgg gcctccggtt gtatcgccgc ctttcaggac gccagtatgc
     2101 tgatgcgcat caaccacgat cccgttagaa ctcatcgctc cgccgccctg ggtaacgcca
     2161 ccattgatca ccacttcgct gttaatgcgc gtgcggtcag cctccagtac aaactcactg
     2221 gttttcatgg tgatgttgtc agcggcctca atgaccattg atttgatgcc cctgacatac
     2281 cagcgcccgg tggcgggttc gtattcaaac cagccaccgt caggatgttc tgtcacgcag
     2341 gcgtctgccg acgtcgacgg tggtgcgaac tgattcgaat agacagcggg cagcgcaaag
     2401 gcagtttcca gattgccgcc cagactcagt agcaccacct gctcaccttc cgatggtttc
     2461 caccatgtgc gggcattacc cgcgcgcagc gtcagccagt taatccagtt ggtttcaagg
     2521 tcgcccgttt tcacccgaca aagccagtgt tcccggtcca cttcggtgac tacaccagtg
     2581 cggatcagat tggtgataag gcgcatgatt tcggttaatt gtgcgttcat agggaaaggt
     2641 tgccatcagg ggaagaaagg cggcagtgct gcaacttgta tcagtgctga tacaaagatc
     2701 accccgccag ccattgcaga atcatgtcgc gggtcattgc ctcaacatca tcatttacac
     2761 ccagcaggcg acgctctgcg taacggacct ccggtccttt gcgactgacg cgatcacgca
     2821 ggccgtaatg gtgaacacgg gcaatacgct gcaccttgcc ttcaaactgt acactggcag
     2881 agtcggcgct ggcggcagtt ttcaggtatt ttgtggtgcg cagctttgca aacatctgac
     2941 gtttgatgcg ccctttcttg ctgcgtgctg ttaccctgcg cggttcataa ctgctgccat
     3001 ctggattgcg ctgcatcctg atattctgct gctgtgtccg gcgcagttcc tgcgccagct
     3061 ggcgcatcat gcggcttctc gtggctggtt ccagattcgc cagcaaggca ctcagccagt
     3121 cgtccacctt ctgcagttca gccacgtttc accgtccaca tttcttcagg ttcatcgggt
     3181 tctgctacag cttcaacgct cgacacactg ccgtcagtgc tgaccagcac acgttccgtc
     3241 agttgcagat taaggctgat atcacagaca tcgttgcgca aaatatccac atcaaaggtg
     3301 aatagctttt cccgtaacgc cgggttattg atggcatcgg gctggttatc ccgaagccac
     3361 agtaaaaccg gggccatcag cagattctgg tcgccgctga aatcctctat caccacgttc
     3421 agggtatagc ggtactccca tgacatggag ctggcccccg tggcaaccag cgaaccgtta
     3481 tccacaaaca gatgcagttt gtccgggtta ttgcggacat aaggcaccgc tttattgagg
     3541 gcgtggcgca gggattgtgg tttgttcact gtttcgctcc tgacacgcaa taatcatgtc
     3601 cactttgtct gcacagaccg cccaggcggc ctccgtttca tccagcaacg cattcagatc
     3661 gccgttactg cgcggcgctg acctttccag gcggcactgc gtcactctgg gacagccact
     3721 cacggtaagc tgcacctccg gcgagggccg ggcggtcccg caacctgata atgtcagcag
     3781 gcaaaggagt gtcagcccag cggcgtaaat cctcgttttc actttttagc tcctcgatcc
     3841 ggcgctggcg acttcgcaac agtgcggtgg tctgctccgc agccgcataa agccgcgtct
     3901 gctcccggct gttggtttcg gtcagaatgg acaggccgat cagctggctg tttttcttcg
     3961 tcagctcctg cgttttgctt ttcagcgccg cgccctgcgt ttcgatggtg tggctggcat
     4021 tgtttaaccg ccacgactgc cagcccagcg ccgcaagtgc cagcgccagc actaccgcca
     4081 gcgcacgcat caggccgcca tcggctcatg aagctgcgag cgggcaatct gatacaaaac
     4141 cagcgtcagc aggtaaaaca ccagggtgat cacccatccc gaaaacgcca ggcacagaac
     4201 aataagcagc ctgatagccc atgtacgcac gggttttacg gggtgcgccc tgaatttgat
     4261 taatgccgcc ctgacctcat cgcgcgcccg atctccggcg aaccacccga cagcgcacag
     4321 cgcagcaagc agccaggcga ggaagcatga cacctggaca gacgcaccaa ccagaaccgg
     4381 cgcaccgctg cgcggataca gcaggctgat taccaacagc gcagcccatg ccagctggaa
     4441 aaaaacgctc atgactttct ttttcattcc gttaggctcc ttttaagcac caggccattt
     4501 cccgcgcgcg gcggttgtcc agcccctgat taaacacacc tttgacatat acccagcgcg
     4561 gcagctgatg gcaggcatcc gcccagcgcc gctggttcag caacttaacc agcgtggagc
     4621 tgcaggcgtt gccggtgccc acgttgaaag caaacgacac caccgcgtca tagacctttt
     4681 gcggcatcgg ctgcaccaca catttttcca gcgcccgctc cacgcgcagc acattggtga
     4741 taagtccctg cgccgcctgc cgttccgtga tggtttttcc aggcaccaca ccggacgtat
     4801 tgccgatccc gtcagtccag acgcccgcgc tacactgata aggctgcagg cggcatccct
     4861 cgtaatcggc gatcagtttc agcccctcaa cggaggtatg aagcgactga aatccgggca
     4921 gcgtggctgc gatagccagc actgccccga caaggcagca cttaacgatt gaagtattca
     4981 tattcccccc gcgaaatctt gccgccacgt aacaatttga aagactggtg tttgtagtac
     5041 cagttgatag ccagcatcag cacaccaatc agtacgccgc caaccgttga cgcatccttg
     5101 agcgacagat cgcccagcca tgccagcagc acggcaatgc agtaagtgat aaaggcgctg
     5161 attcgttcaa gcgtcataat tcagtcccat agctggacgg tctgcgccgt ggttgacgcc
     5221 gtaatgtccg gcagctccac ctgcagcccg tgcggtaaaa atgggccgta ctcagccagc
     5281 cccggatttg cctgcagaac ctgctcagtg acaccctgcg tgcgcccgta atgacgccag
     5341 caaagcgcgt ccaccgtgtc atactgatgc gcacgcactt tcatcagata agctccaccg
     5401 tacagtgcgg tgcatcctgc acccggctga tggcccagcg ggcatcacgc cacagatcgc
     5461 cgctggcctc cgccagctcc tcccctcgct tcacgcctga cgccgtggcg tcatagtcct
     5521 gataacgctc attaagcaca gcgcgcgccc agcaaaaaac agcgttgtgg tagtgccgga
     5581 tacgctcgct tttaccgtcc agcatttctg cgggaacctc agcaagtgtc cgccagccca
     5641 gcatctgctg acggttgcgg aagtcgtaca gctcagcgtt aacctcagag atcgccgtca
     5701 gcacgacctg ctttaaacgc ggctgcgtca ccgtgccgtc agtgcgcatc acactgcgaa
     5761 attccgacag gttcacatca ggccagaacg gcgtattttt gatgacctcc gcctgttccg
     5821 gtgcctgttc tggcgcaaca aacttcatgc ggcgttctcc tgaataagtg ggcggtggac
     5881 ggaattttga tgtggcagtg cctttcgcca tcccgtgccg cccgtgcgcg gggcacgttc
     5941 gttagcggct gtcattgcgc agtctgcgct ccagctgctg cttttctttt ttcacaccgc
     6001 agcggggatc aagctgcagc gcatggttaa ggtgattcag ggcagacgcc gggttgcttt
     6061 cgctcagtac agcaccgatg gctttatgca ggcgcgcccg cgactggtcc ggcatatcca
     6121 gatcggtggt caggtccagc gtctgcagaa gcggatcggc atcaaaaccg gcagcggcaa
     6181 gcagagcgct ttgcgccgcg tctgccattt cttctgccag cacggtctgc acgttacggt
     6241 tgcccagagg catcacccag ccatggcgca gcgcatggcg cccgatttcg agcgcaccgg
     6301 cataatcacc ggcgtcgata cgccacagca tcacgtacat cagcacgtca tcctgctgcg
     6361 cacctccggc agccagcacg ccctccgccc aggcggaata tttcggcagc agttccacct
     6421 tgatttccgc ctttttcacc gtggactgga cgcccttgag gcggcggcgg tcttctgcca
     6481 gctgcagcag catcaggtca tagcccgacg catggcgaac actgccgccc tcacgggcgg
     6541 cctgttcagc ctgaatgcgc aggcggtgct gccgtgcggg actcaggctc atgcgttatt
     6601 ccccactttc cggtgcggca ggcgcgctga aatcaccgat ttcgatgttt tctaccagcg
     6661 ccgcgcagcg gtagtcctcg accacatacg cctcgttgac ggattcaaag ttttcaatcc
     6721 ggtcgcgttt cgggttgtcg ataactgaac ggcggcgggt gtcttcctgc cagtagatgg
     6781 acaggttatc cagacgggtg atcagcaggg catttgccgg gaagaaaggc gcgcgcacag
     6841 cctgcaggcc gcccatgcgt ttctggctga tgatcagatc ggcggcgatt ttctcgctgt
     6901 tgtcctgctc tttgttgacc agcgggaaat acttgtcaga cagcagttca cgtccgcaga
     6961 caacaaccag ctcgtcatca tcctgatact ccacatcgat cagctcgttg acggtatcca
     7021 tcaccaccgc gtcaagattt acatacttac cacccggacc tacttttact ggttctgcag
     7081 tagtggtgcc gtcttctgcg gttttgctgc ccatgacgtg atccggcgcg tcttcgcgga
     7141 ttttctgcag ccagccttta ttgacgtcct gcagcagcgg gttttcagca cggttggagg
     7201 ttttggcgcg cttcacgccg ttaaagccga tcatgatgcg gtccagcgcc tgacgcttga
     7261 cgatggcgtt gcggatacgc acctggaagt cctggaattt cgcccacagg tccagttttg
     7321 cgtaggtcag caccgtatca aagttggtct gctcgcattt gtattccacg tcttccatca
     7381 gcgtcggatc ggtaggctcg cgctctttgg tggtggtatc ggtggttccg gcaatggtgc
     7441 tgccaacgcc cagccccagc aactgaccgg actgctcagt gaccggcgtg atgttaatca
     7501 gcgtcaggaa agcagcagac tgctggatgt ggtcttccag agtctgctgc acggacggct
     7561 ccacggtgaa cttgctggag agttcttcaa catccacacc attcaggcgc gccagctgct
     7621 gcaggtaagc gttaaaggca aagcgggttt tctttttcat cgggttttat gctccatcag
     7681 caattggtca gggtgcctgc cggtgcgtca ccgcccggcg cgcgctggcg gtaatccttg
     7741 cggctgtctt cgcggctcag ttgctgctgt agctcggcaa aggcggtctg ctgttcctgc
     7801 agggaggact ccagcgcgga aaggcgctca ccgttttcag ccagggattt atcagtgcgc
     7861 tcgctcaggt tctgctgctc ggtggcgaca agttccacgg ctttatgcac atcggagaaa
     7921 cgcgcatcgt cggtctgctc ttttttggtg aacagcgcgg tgacgctggc aaagagggac
     7981 ggcttttcgt cctgggcttc ttccagttcg atcagcgttt caaccgcttc cgaaaacagg
     8041 ttttcagggt tctgcttacg gtttgccagc gggttatgtg cggcgctggc gctgaaagcc
     8101 agcatttcgg tgccaaggct cgcaggatcg tccgtcgcac ccagccccac aaggtaggct
     8161 ttgccggtgt cggcaaactt cgtgctgacc tccatggagg tgaaaagctt ctggcctttt
     8221 ttcaccagtt ccaccagggc gtcagtgggt tcgatatcgg cataaagtgc catcttgccc
     8281 gccagcgggc cgtcctggat ttcttctgca accagccccg tcaccctgcc atagcggtta
     8341 aaagtgctct ccggcagata agacttgatg tgctcaaggt taatcagcgc ggtatagacc
     8401 gtcgggttgt agctggcagc catctgtacc agccattcac gctggatctc gcgcccgtca
     8461 gtggtggcac cttccacccc gatgcggaaa cgctttgctt tcactgtcat gagccgtgct
     8521 ccgttagaaa taacttactg gagtcttatg tttgcggtga tggggggagt gagacaacgc
     8581 gctgtatttg tacggtaaac cacacaaacc gcagccgggg aaagccgcca tccaaggccg
     8641 tatgtttggg ccatgaacac gacactgacc cccgcagacc tcgatccccg tcggcaggcc
     8701 atgctgctgt actttcaggg ataccgcgta gcccgcattg ctgaaatgct gggcgaaaaa
     8761 gttgcaaccg ttcacagctg gaaaaaacgc gacaagtggg gcgactatgg gccgctggat
     8821 cagatgcagc tcaccaccgc cgcacgttac tgccagctca tcatgaagga gcagaaagaa
     8881 gggaaagact tcaaggaaat tgacctgctg gcgcgccagt cagagcgtca cgcccggatc
     8941 ggaaaattta acgacggcgg gaacgaagca gatttaaacc cgaaagtagc caaccgtaac
     9001 aaaggtccgc gcaggcagcc ggaaaagaac gttttctccg acgaacagat cgaaaagctg
     9061 gaagaagtct tccacgcctc aatgttcgac tatcagcgtc actggtttga agcaggaaaa
     9121 ataaaccgca tccgtaatct gctcaagtcg cgccagattg gcgccacgtt ttattttgcc
     9181 cgtgaagcat tgattgacgc cctgctgacc ggacgcaacc agattttcct ttctgccagt
     9241 aaggcacagg cgcacgtctt taagcagtac atcatcgact ttgcaaaaga agttgaggtg
     9301 gagctgaaag gcgatcctat ggtgctaccc aatggcgcag cattgtactt tctcggcacc
     9361 aacgcccgta cggcgcagag ctaccacggc aacctgtacc ttgatgaata tttctggata
     9421 ccgaaattcc aggagctgcg caaggttgcc tccggtatgg ccattcacaa gaaatggcga
     9481 caaacctact tttccacgcc gtccagcctg acccacagtg cctatccgtt ctggtccggc
     9541 gcgctgttta accggggccg agccaaagcg gacaaggtag atattgacct gacccacagc
     9601 aaccttgcac gcggcctgct ctgccctgac ggacagtacc gccagatcgt caccgtggag
     9661 gatgcggtgc gcggcggctg taacctgttc gacctcgacc agctgcgcat ggagtacagc
     9721 ccggacgaat accagaacct gctgatgtgc gaatttattg acgatctggc gtcagtattc
     9781 ccgctcagcg aactgcaggc gtgcatggtg gacagctggg aagtctggac cgattttcag
     9841 gcgctggcgc tgcgcccgtt tggctggcgc gaagtctgga tcggttatga cccggcgaaa
     9901 ggtacgcaga acggtgacag cgcaggttgt gtggttattg ctccgcccac tgtaccgggc
     9961 ggaaagttcc gcattctgga gcgtcatcag tggcgtggga tggacttccg cgcccaggct
    10021 gacgccatta aaaagctgac acagcagtac aacgtgacct atatcggcat cgactcgacc
    10081 ggcgtcggtc acggtgttta cctgaacgta aaagactttt ttccagcagt acgagagttt
    10141 gtctacaacc ccaacgtcaa aaacgccctg gtgctcaagg cgtacgacat tatcagccac
    10201 cgccgtctgg agtttgacgc cgggcatacc gacattgcgc agtcctttat ggctatccgc
    10261 cgggccacca ccgccagcgg caaccgccca acctatgaag ccagccgcag cgaagaagcc
    10321 agccacgcag atttggcctg ggcaacgatg cacgcactgt ttaacgaacc gctgcagggc
    10381 gaagccgcca ataccagcaa tattgtggag attttttgat gagtgaacac gacgccctga
    10441 ccagcaccgc gccagtgcag gaggccgaac agcagaagaa tacaactcac gccgaagcgt
    10501 tcagctttgg cgatccgatc ccggtactgg accgccgcga actgctggac tatgtggaat
    10561 gcgtacagat ggacagatgg tatgagccgc cagtaagctt tgacgggctg gcgcgaacct
    10621 accgcgccgc tgtgcatcac agctcaccga tagcggttaa gcgtgacatt ctcagcagta
    10681 cgtacatccc gcaccgcctg ctcagccagc aggcttttgc ccgtttcgtc caagattatc
    10741 tggtgttcgg taacgcctat ctggaaaagc gcaccaaccg gctcggcggc gttctctcac
    10801 tggagccagc actggcgaag tacacacgcc gtggcttgga cctcgacacc tactggtttg
    10861 tgcagtacga cctgaccacg cagccctatg aatttacaca gggcaacatc tttcacctta
    10921 tggagccgga tattaaccaa gagatttacg ggctgcccgg ctatctctcc gccattccgt
    10981 caaccctgct caacgagtcc gcaacgctgt tccgccggaa gtattacatc aacggcagcc
    11041 atgcggggtt catcatgtat atgaccgatg cagcacagaa tcaggaggac gtgaacaata
    11101 tccgccaggc aatgaaaagc gccaaagggc cgggcaactt ccgcaacctg tttatgtact
    11161 cgcccaatgg taaaaaggac ggcatccaga tcatcccgtt gtcggaagtt gcggcaaagg
    11221 atgagtttct taacatcaag aacgttagcc gcgatgacat gatggcagcg caccgcgtgc
    11281 caccgcagat gatgggcatc atccccaaca ataccggcgg ctttggtgat gtggaaaagg
    11341 ccagccgcgt gtttgtacga aatgaattaa taccccttca agaaaggatt aaagaactca
    11401 atgaatggtt aggggatgaa gtcattagat ttgcgaaata tacactcgac gacataagct
    11461 aattttatta taaaagatgg tgccatcata taacgatgac accatcgccc ctaaaattta
    11521 tcaatttcca tacatgaaat agcatcattg aaaatcgaaa aatgctcatc aggaaccact
    11581 gcagaagccc cactggttaa ttcaaaacta atctttgaat caaggtaaaa ccctcctgct
    11641 tttattttat cgagcttgaa ttcactatcc ccaacaaaaa tcttcaaatc atgcaaagca
    11701 tcgccgctag aattcaattc caaacatgct cttgtttttt cagtaacagg aagatttgac
    11761 accttcactt tggaaatgcc aaacaccttt acgccgaaat tttctcgaat gaccctcatg
    11821 aaagctttaa gatctacggt taaattccca taagcaacat ttaacccttc ggcctgagac
    11881 aaaaaatcga taaaaggttt aactgttttt ggaggattgt aaaaagttaa caaacatatc
    11941 ttattgctga gggtttggat agaaaaacta atctgatcaa atacaaccct ttcgaattcc
    12001 agcacctcac caaatggatc ggcaatcggc tctaaaacaa cagatttttt attgaaagtt
    12061 gcagtcatac cattatgaat ggtttcatac ttagtaaaac cagcaccaat agcatcagaa
    12121 taaggcgtgt ttttga
//
LOCUS       DAJVKX010000133        12058 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.133, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000133 DAJVKX010000000
VERSION     DAJVKX010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12058
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.133"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(99..1928)
                     /gene="glmS"
                     /locus_tag="OPY25_003682"
     CDS             complement(99..1928)
                     /gene="glmS"
                     /locus_tag="OPY25_003682"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCS0929186.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGII
                     ENHEPLREALKARGYTFVSETDTEVIAHLVNWELKQGGTLRDAILRAIPQLRGAYGTV
                     IMDTRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDNTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADDLLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIELLAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFSDQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(2117..3487)
                     /gene="glmU"
                     /locus_tag="OPY25_003683"
     CDS             complement(2117..3487)
                     /gene="glmU"
                     /locus_tag="OPY25_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCS0929187.1"
                     /translation="MLNSAMSVVILAAGKGTRMYSDIPKVLHTLAGKPMVQHVIDAAT
                     KLGAAQVHLVYGHGGELLKQTLKDDKLNWVLQAEQLGTGHAMQQAAPFFSDDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPSGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADLKRWLSKLTNNNAQGEYYITDIIALAYQEGREIAAVHPA
                     RISETDGVNNRLQLSRLERIYQAEQAEKLLLSGVMLRDPARFDLRGTLYCGMDVEIDA
                     NVIIEGYVTLGHRVKIGAGCIIKNSVIGDDCEISPYSVVEDAHLEAACTIGPFARLRP
                     GAELLAGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTVIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVADNELVLSRVPQVHKQGWQ
                     RPVKKK"
     gene            complement(3807..4505)
                     /locus_tag="OPY25_003684"
     CDS             complement(3807..4505)
                     /locus_tag="OPY25_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCS0929188.1"
                     /translation="MSFQPSFAGPQPDSRIDRTTFIRRAYLHLAVAIVGFIVLSAAWS
                     FIGGGEYALDVLLAGGRYSWLVVLGAFMLVGMLATRLADNAGTNQTQLIGLGIYVLAE
                     SLIFAPLLTVAAYINPSSIGAAAITPLLLVGGLTFTAFSIKKDFSFLRSFLTMAGFIA
                     FGAIIASVICGFSLGVWFSALMVLLCAGFILYDTSNIIHHYPTDRPAGAALHLFASIA
                     TMFWYILRIFMSRN"
     gene            complement(4734..5153)
                     /gene="atpC"
                     /locus_tag="OPY25_003685"
     CDS             complement(4734..5153)
                     /gene="atpC"
                     /locus_tag="OPY25_003685"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCS0929189.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGSVTVLADTAIRGQDLDEARALEAKRKA
                     EEHIKSSHGDVDYAQASAELAKAIAKLRVIELTKKAM"
     gene            complement(5174..6556)
                     /gene="atpD"
                     /locus_tag="OPY25_003686"
     CDS             complement(5174..6556)
                     /gene="atpD"
                     /locus_tag="OPY25_003686"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCS0929190.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     DEAVEKAKKL"
     gene            complement(6583..7446)
                     /gene="atpG"
                     /locus_tag="OPY25_003687"
     CDS             complement(6583..7446)
                     /gene="atpG"
                     /locus_tag="OPY25_003687"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCS0929191.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAVSKMRKSQDRMAASRP
                     YAETMRKVIGHLANGNLEYKHPYLEERDVKRVGYLVVSTDCGLCGGLNINLFKKLLAD
                     MKAWSDKGVQCELAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTITQLLPLPASEDDDLKRTAWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(7497..9038)
                     /gene="atpA"
                     /locus_tag="OPY25_003688"
     CDS             complement(7497..9038)
                     /gene="atpA"
                     /locus_tag="OPY25_003688"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCS0929192.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(9051..9584)
                     /gene="atpH"
                     /locus_tag="OPY25_003689"
     CDS             complement(9051..9584)
                     /gene="atpH"
                     /locus_tag="OPY25_003689"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCS0929193.1"
                     /translation="MSEFVTVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENNRLNALPDVLEQFIHLRAA
                     SEATSEVEVTSATALSEEQLSKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(9599..10069)
                     /gene="atpF"
                     /locus_tag="OPY25_003690"
     CDS             complement(9599..10069)
                     /gene="atpF"
                     /locus_tag="OPY25_003690"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCS0929194.1"
                     /translation="MNLNATILGQAIAFILFVWFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRAQILDEAKTEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(10129..10368)
                     /gene="atpE"
                     /locus_tag="OPY25_003691"
     CDS             complement(10129..10368)
                     /gene="atpE"
                     /locus_tag="OPY25_003691"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HCS0929195.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(10415..11230)
                     /gene="atpB"
                     /locus_tag="OPY25_003692"
     CDS             complement(10415..11230)
                     /gene="atpB"
                     /locus_tag="OPY25_003692"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCS0929196.1"
                     /translation="MASENMTPQEYIGHHLNNLQLDLRTFSLVDPQNPPATFWTLNID
                     SMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHWLGLPATRVVPSADVNITLSMALGVFIL
                     ILFYSIKMKGIGGFAKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYSG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(11239..11619)
                     /gene="atpI"
                     /locus_tag="OPY25_003693"
     CDS             complement(11239..11619)
                     /gene="atpI"
                     /locus_tag="OPY25_003693"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HCS0929197.1"
                     /translation="MPVSLVSRNVARKLLFIQFLAVIASGLLFCLKDPFWGISAVCGG
                     LAVALPNMLFMIFAWRHQAHTPAKGRVSWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
BASE COUNT         2953 a         3345 c         2937 g         2823 t
ORIGIN      
        1 gttattctca tctcccgtaa atatttttta tttttgttca aaaaactcat aaaaaaaggc
       61 cgtctatcga cagccttttt tttggtacaa catttgactt actctaccgt caccgatttc
      121 gccaagttac gcggctggtc aacgtcggtg cctttaatca gcgccacgtg atacgccagc
      181 agttgcagcg gaacggtgta gaagataggc gcaatgacct cttccacatg cggcatctca
      241 atgatgtgca tgttgtcgct gctcacaaaa cccgcatcct gatcggagaa gacgtacaac
      301 tgaccgccac gcgcgcgaac ttcttcgatg ttggatttca gtttctccag cagttcgttg
      361 ttcggcgcca ccacaatcac cggcatatcg gcgtcaatca gcgccaacgg cccgtgtttc
      421 agctcgcctg cagcataggc ttccgcgtga atgtaagaga tctctttcag cttcagcgcg
      481 ccttcgagcg caatcggata ttgatcgcca cgaccgagga ataacgcgtg atgcttgtca
      541 gagaaatctt ctgcaagcag ctcgatgcgt ttgtcctgcg acagcatctg ctcaatacgg
      601 ctcggcagcg cctgtaggcc atgcacgata tcatgctcaa tggacgcatc cagacctttc
      661 aggcgagaca gtttcgccac cagcatcaac agcacggtta actgggtggt gaaggctttg
      721 gtagatgcta cgccaatttc cgtacccgcg ttggtcatca gcgccagatc ggattcacgc
      781 accagcgaag agcccggcac gttacaaatg gccagagagc ccaaatatcc cagctctttc
      841 gacagacgca ggccagccag ggtatctgcc gtttcgccag actgggagag cgtgatcatc
      901 aggctgttac ggcgcacggc agatttgcga tagcggaatt cagaggcgat ttcaacgtcg
      961 cacggaatac ctgccagcga ttcaaaccag taacgggaaa ccataccgga gttgtaagac
     1021 gtaccgcagg cgaggatctg aatatgctca accttcgaca acagatcatc ggcgttcggt
     1081 cccagctcgc ttaaatccac ctgaccgtgg ctgatgcgcc cggtaagggt gtttttgatc
     1141 gcgttcggct gttcgtagat ctctttctgc atgtagtggc ggtaaatacc tttatcgccc
     1201 gcgtcatatt gcagattgga ttcgatatcc tgacgtttta cttccgcgcc ggtgttatcg
     1261 aagatattta ccgaacggcg agtgatttca gcgatatcgc cctcttcaag gaagataaag
     1321 cgacgagtca ctggcaacag cgccagctgg tcagaagcga taaagttttc gcccataccc
     1381 aggccaatca ccagcgggct acctgaacgg gcagccagca gcgtatccgg atggcgggta
     1441 tccatgatca ccgtgccata tgcgccacgc agttgcggga tcgcacgcaa aatcgcgtct
     1501 cgcagagtac caccttgttt cagttcccag tttaccaggt gtgcaatcac ttcggtgtcg
     1561 gtttcagaaa cgaaggtata gccacgcgct tttaacgctt cacgcagcgg ttcatggttt
     1621 tcgatgatgc cgttatgcac caccacaatg tgttcagaaa catgcggatg cgcgttagct
     1681 tctgaaggtt caccgtgcgt cgcccagcga gtgtgagcaa taccggtgcc gccatgcagc
     1741 gggtgttctt ccgctgcctg agccagcatc tggactttac cgaggcgacg caggcgggtc
     1801 atatgacctt ctgcatccac cacggccaga ccggcagagt cgtaaccacg gtattccaga
     1861 cgacgtaaac cttcgagaag gatttcagct acatcacgct gcgcgatagc gccaacaatt
     1921 ccacacatag ttttatttcc tgattatggc attacgccat gcgttgtcgc tgacctgtat
     1981 gcccgtcgtt gcgggcgccc cgagccttgt agagagtggg gttattttta taagtactgc
     2041 tcatggagcg gaggattatt ttatcctctc atctccggtc tgccggatgg cgctgacgct
     2101 tatccggcct acaaaatcac tttttcttca ccggacgctg ccagccttgc ttatgcacct
     2161 gcggcacgcg gcttaatacc agttcattgt cggctacatt acgggtgacg gtagtccctg
     2221 cggcgatggt ggccccttta ccaacagtaa ccggcgccac cagttgggta tcggagccga
     2281 caaacacatc gtcgccaata accgttttga atttgttcgc gccatcatag ttacaggtga
     2341 tggtccccgc gccaatattc acgttgtcgc caatttccgc atcgcccagg taggtcagat
     2401 ggccggcttt agaaccttta cccagacgcg cttttttcat ttcaacaaaa ttgccgacgt
     2461 gagcgcccgc taacagctca gcgccgggac gcaggcgagc aaacgggccg atggtgcagg
     2521 ccgcttccag atgcgcatct tccaccacgc tgtatgggct aatttcgcag tcatcgccaa
     2581 taacgctgtt tttaataatg cagcccgcgc cgatcttcac gcggtgaccg agcgttacat
     2641 aaccttcgat gataacgtta gcgtcaattt cgacatccat tccacaataa agggtgccgc
     2701 ggagatcaaa acgtgccgga tcgcgcaaca taacgccgga taacagcagt ttctccgcct
     2761 gttcggcctg gtaaatacgc tccagacgag aaagctgtag acggttattc acgccgtccg
     2821 tttcgctgat gcgagccgga tgcaccgcgg cgatttcccg tccttcctga taagccagcg
     2881 cgatgatatc tgtgatgtaa tattcaccct gcgcattatt gttagtcagc ttagacaacc
     2941 agcgtttcag gtccgcgccg ttggcgatca gaataccagt gttaatttcc tggatctgac
     3001 gctgttcatc agtggcgtct ttatgttcaa cgatgccggt cactttaccg ttttcacgcg
     3061 taatacggcc atagccgctc ggatcgtcca gcttcacggt taataaccca ataccaccct
     3121 gcggtttggc atcgcgcagg cgctgtaagg tttcaaccga aatcagcggc acgtcgccgt
     3181 aaagcattaa aatatcttca tcgtcgctaa aaaagggcgc ggcctgctgc attgcgtgac
     3241 ctgttcccaa ctgttccgcc tgaagcaccc agttcagctt gtcatctttc agggtctgtt
     3301 ttaacaactc gccaccgtgg ccatagacca gatgaacctg tgcggcccct aatttagtag
     3361 ctgcatcaat gacatgctgc accatgggtt tacccgccag cgtgtgcagc actttaggaa
     3421 tatcggaata catgcgcgtg cctttacctg cggcaaggat cactacgctc atagcactat
     3481 ttaacatacg cgtcctgact gtaatttgag aacgaattta tactgtttca cgttgaaaat
     3541 actacatttt tttcatcgta aaatggaaga aggataaaac gctcaccggg ataaaatccc
     3601 cgcctgctaa tgaatcattt tcgttcatta ccgcgcctct tgtctcctga aaagtaaaaa
     3661 cacccgcgta ttggcaacgt agtccgatgt ttttgctgtt tttttactcc ataaataaag
     3721 aagataacga aataaagcgc aggggagtca gaaaagcaaa aaccagcgac agaggccgct
     3781 ggttttccgt tgcgcgtatt ttttacttaa ttacgcgaca taaaaatccg taaaatatac
     3841 cagaacatgg tcgcgataga agcaaacaga tgtaatgccg cgccagcagg gcgatcggta
     3901 gggtaatggt gaataatgtt agaagtgtcg taaagtataa acccggcgca cagcagtacc
     3961 attagcgcag aaaaccagac gcccagcgaa aagccgcaga tgacgctggc aataatcgcg
     4021 ccaaaagcaa tgaatccagc catagtcaga aacgagcgca gaaaagaaaa gtcttttttt
     4081 atggaaaacg cggtaaacgt cagaccgcca accagcaaca ggggcgttat tgccgccgcg
     4141 ccaatgctcg acgggttaat atacgccgcc accgttaaca ggggggcaaa aatcagggat
     4201 tctgccaaca cataaatccc cagcccgata agttgcgttt gattagtccc cgcattatcc
     4261 gccagacggg tcgccagcat tcccaccagc ataaaagcgc cgagaacaac caaccagcta
     4321 tatcttccac cagccagcag cacatcaagc gcatactccc cgccccctat aaaactccac
     4381 gccgcgctca acacgataaa accgacgatg gcgacggcga gatgaagata agcgcgacga
     4441 ataaaggtag tacgatcaat ccttgagtcg ggttgtggcc ccgcaaagga tggctgaaat
     4501 gacatagtaa taatccctca ttttatgcaa taaaaacgca tccattcctt ccttcttcgc
     4561 acaatgtgca gatgccaatg acagaaagaa ggatttaatg aaaacagcgc tgtcgctgaa
     4621 aacgcatcgc cttcagccgc ttgtttttgt cgttgctagt ttatcgaata aaaattgaga
     4681 ggataaaaaa aaccagtccg caatcagact ggttttatgc tttcaagccg gtgttacatc
     4741 gcttttttgg tcaactcgat aacgcgcagt ttagcgatcg ctttggccag ttccgcagac
     4801 gcctgagcgt aatccacgtc accgtgcgag ctcttaatgt gctcttcggc tttacgcttc
     4861 gcttccaggg ctcgcgcttc gtcgagatcc tgaccgcgaa tcgcggtatc cgccagaacg
     4921 gtcacactgc caggctgcac ttccagaatg ccgccggaca gatagataaa ctcttcgtga
     4981 ccgtgctgct taacgatgcg aatcatacca ggcttaatgg cggtgagcag cggcgcgtgc
     5041 cccgggtaga tccccagttc accttcgcta cccgtaacct ggattttctc gaccagaccg
     5101 gagaacattt gttgctccgc gctgacgaca tccaggtggt aagtcattgc catatcaccc
     5161 tccgattaag gcgttaaagt tttttggctt tttccacggc ttcgtcgatg gaaccgacca
     5221 tgtagaacgc ctgctccggc aggtgatcgt attcgccttc catgatgcct ttaaagccac
     5281 ggatggtgtc tttcagggag acgtatttgc ccggagaacc ggtaaatact tccgccacga
     5341 agaacggctg ggacaggaag cgctggatct tacgcgcgcg agctaccacc agtttatctt
     5401 cttcagacag ttcatccata ccgaggatgg cgatgatgtc tttcagttcc tgataacgct
     5461 gcaggatgga ctgaacgcca cgcgcggtgt cgtagtgttc ctgaccaaca accagcggat
     5521 ccagctgacg gctggtggaa tccagcgggt caacggccgg gtagataccc agggatgcga
     5581 tctgacggct cagtaccaca gttgcatcta agtgcgcaaa ggtggtggct ggagacgggt
     5641 cagttaagtc atccgcaggt acgtataccg cctgtacgga ggtgatagaa ccggtcttgg
     5701 tggaggtgat acgttcctgc agaacgccca tctcttccgc cagagtcggc tggtaaccta
     5761 ccgcggaagg catacgaccc agcagtgcgg atacttccgt accggccagg gtgtaacgat
     5821 agatgttatc gacgaacagc agtacgtcac gaccttcgtc acggaatttc tccgccatgg
     5881 tcaggccggt cagtgcaacg cgcagacggt ttcccggcgg ctcgttcatc tggccataca
     5941 ccagggatac tttatcgata acgttggagt cggtcatttc atggtagaag tcgttaccct
     6001 cacgagtacg ttcacctacg cccgcaaaca cagagtaacc ggagtgctcg atcgcgatgt
     6061 tacggataag ctccatcatg tttacggttt tacctacacc cgcaccaccg aacagaccga
     6121 ctttaccgcc cttcgcgaac ggacacatca ggtcgataac tttgataccg gtttccagca
     6181 gttcctgaga gtttgataac tcttcgtagg aaggcgctgc gcggtgaatc gcccaacgct
     6241 cttcttcgcc gatctcgcct ttcatgtcga ccggttcgcc caggacgttc atgatacgac
     6301 ccagcgtagc tttacctacc gggacttcga tcgggtgttc gagatctttt acatccagac
     6361 cgcgacgcag accgtcagaa gaccccatcg cgatggtacg cacgataccg ccgccaagct
     6421 gctgctgaac ttccagcacc agcttctcat taccattctg cacctcaagg gcatcgtaca
     6481 cgcgtggtac ggcatcctga gggaactcga cgtctaccac ggcgccgatt acctggacaa
     6541 tctttccagt agccatctta aatcctctac gaaataacct ggttaaaccg cggcggcccc
     6601 cgagacgatc tcggtgagtt cctgagtaat gctggcctga cgagctttgt tgtatactaa
     6661 ctgcagctct ttaatcaggc tgccgccatt atcggttgcg gctttcatcg ccaccattcg
     6721 tgcggcctgc tcgctggcca ggttttctac cacgccctga taaacctgag actccacata
     6781 acgacgcagg agagtatcca gcagcgcttt cgggtctggt tcatacaggt aatcccaggc
     6841 tgtacgcttc agatcatcat cttctgacgc cggcagcggc agcagttgag tgatcgtcgg
     6901 cacctgagac atggtgttaa taaatttgtt gctgacaatg taaagcttgt ccagacggcc
     6961 ttcgtcgtag gcctgcaaca tcactttaac cggaccgatc agttcggaca gagaagggtt
     7021 atcccccata cctgtcacct gagcgacaac gttgccgcct acggaattaa agaatgacac
     7081 gcccttagag ccgatcattg cgagttcgca ctgaacgcct ttatcggacc atgccttcat
     7141 atccgccagc agctttttga acaggttaat gttcaagcca ccgcacaaac cacagtcggt
     7201 cgacactacc aggtagccca cgcgtttaac gtcgcgctct tccaggtagg ggtgcttata
     7261 ttccagatta ccgttcgcaa ggtgaccaat cactttgcgc atggtctctg cataaggacg
     7321 gctggccgcc atgcgatcct gcgatttacg cattttggaa acggcgacca tctccatcgc
     7381 tttagtgatc ttttgcgtgt tctggacgct tgcgatctta ctacgtatct cttttgcgcc
     7441 ggccatgagc ttctcctcaa tgccttacgg cctgccctaa ggcaagccgc cagacgttac
     7501 caggactggg ttgctttgaa ggaatcgagg atgcctttca gcttgccttc gatttcgtcg
     7561 ttatagccac cggactggtt gatctcttgc atcagcggag cgtgatcacg gtcgacgtaa
     7621 gccagcagtg cggcttcgaa gctaccgatt ttcgccagtt cgacatccgc cagataacca
     7681 cgttctgctg cgaacagaac cagagactgc tgcgcgacgg acatcggcgc atactgtttc
     7741 tgtttcagca gttcggtcac tttctgaccg tggtcaagct gtttacgggt ggcatcgtca
     7801 aggtcggatg caaactgaga gaacgccgcc agttcacgat actgcgccag cgcggtacga
     7861 atacctccgg acagtttttt catgatcttg gtctgggctg cgccacctac acgggatacc
     7921 gagatacccg ggttaaccgc aggacgaata ccggcgttaa acaggttaga ttccaggaag
     7981 atctgaccat cggtaatgga aattacgttg gtcggaacga acgcggaaac gtcacctgcc
     8041 tgcgtttcga taatcggcag cgcagtcagt gaaccggttt tccctttcac ttcaccttta
     8101 gtgaaggctt cgacgtagtc ggcgttaaca cgcgcagcac gctccagcag acgagagtgg
     8161 aggtagaata cgtcgcccgg gaatgcttca cgtcctggcg gacgacggag cagcagggag
     8221 atctgacggt aagcaacagc ctgtttagac aggtcatcgt aaatgatcag cgcatcttca
     8281 ccgcggtcac ggaagtattc gcccattgcg caaccggcat acggcgccaa atattgcagc
     8341 gcagcggatt cggacgcggt cgccaccaca acaatggtgt tagccagcgc gccgtgctct
     8401 tccagtttac gcaccacgtt agagatggtg gacgctttct ggccgatagc gacatagata
     8461 catttgatgc cggagtcgcg ctggttgatg atggcgtcga tagccagcgc ggttttaccg
     8521 gtctgacggt caccgatgat cagttcacgc tgaccacgac cgattgggat catggagtca
     8581 acggctttat agccggtctg caccggctga tcgacagact gacgatcgat aacgcccggc
     8641 gcaatcgctt caacggcaga gaagccgtca ttatcaaccg gacctttacc gtcgattggc
     8701 gcacccaggg tgtttaccac acgtcccagc agaccgcggc caaccggaac ttccaggata
     8761 cgacccgtac atttaacctt catgccttcg gcaaggtcag cgtatggacc catgactacc
     8821 gcacccacgg agtcgcgctc caggttcagt gcgatagcgt aacggttacc cggcagggag
     8881 atcatttcac cctgcataca atcggccaag ccgtgaatgc ggataacacc gtcactaaca
     8941 gaaacaatag taccttcgtt gtgagcttcg ctcaccacat tgaactgagc aatgcgctgc
     9001 ttgatcagtt cgctgatttc ggtggaattc agttgcatgc tccagtcccc ttaagactgc
     9061 aagacgtctg caaggcgctc aagacggccg cgtacgctgc catcaatgac catatcaccc
     9121 gcccggatga taacgcctgc cattacagac ttatcgattt tgcaattcag cttcactttg
     9181 cgtgacagac gtttttccat cgcggcgctg attttcgaaa gctgctcttc actcaatgcg
     9241 gttgccgacg taacttctac ctcggaggta gcttcactgg cggcacgcag atgaataaac
     9301 tgctccagaa catccgggag cgcgttcaga cgattatttt cagccatcac ccgaatcagg
     9361 ttctgaccgt tttcgtctaa ctgctcaccg cagactgcga taaacgactc agcgagcgtt
     9421 tccggcgcca gcgcgccaga gagaagctct gccatttgtt cgttcttggt tacctcggcg
     9481 gcaaacgcca gcatatcctg ccagcgctct acactttggt gttcaacggc aaagtcaaaa
     9541 gctgctttgg cgtaggggcg agctaccgta acaaattcag acatcagccc ctccctcctt
     9601 acagttcagc gacaagttta tccacgatgt cgctgttagc agcttcatcc acggaacgtt
     9661 cgatgatctt ctcggcgcca gcaacagcca ggatagcaac ttgcttacgc agctcttcac
     9721 gggcacgttt acgctcggct tcaatttccg cctgcgcctg cgccacgatt ttagtacgtt
     9781 cctgctctgc ttcagttttg gcttcgtcca ggatctgagc gcggcgtttg tttgcctgct
     9841 cgatgattac ctgagcttcc gctttcgctt ttttcagctg gtcggtcgcg ctggcctttg
     9901 caaggtcaag atccttatgt gctcgttcag cagaagcgag accgtcagca atttctttct
     9961 gacgtttctc gatggctgcc attaacggcg gccatacgta cttcatgcaa aaccagacaa
    10021 agagaataaa cgcgatggcc tggccgagga ttgttgcgtt aagattcaca gcacaatgcc
    10081 tctatctagt taaccttctg atattgctct taattcaagc aacgcttact acgcgacagc
    10141 gaacatcacg tacagaccca gacctacagc gatcatcggg atagcatcca ccagacccat
    10201 aacgataaag aactgagtac gcagcagagg aatcagatca ggttgacgcg ccgcgccttc
    10261 caggaattta cccccgagga tgccgatacc gatcgcagca ccgattgccg ccagacccat
    10321 catcacagcg gcagccatgt acagcagatc catattcagg ttttccatga cagtctccag
    10381 tttgtttcag ttaaaacgta gtagtgttgg taaattaatg ctcttcggac gccatcgaca
    10441 gatagacaat cgtcagaacc atgaaaatga aggcttgcag cgtaataatc aggatgtgga
    10501 aaatggccca cggcacattc agaatccact gtgaccacca cggcaacaga ccagcaatca
    10561 gaatgaaaat cagctcaccg gaatacatgt tgccgaacag tcgcagaccg agagaaaccg
    10621 gtttggacag cagacttacc ccttcaagga ttaagttgac aggaatgaac gcccagtgat
    10681 tgaacggctg cagcgtcaac tcttttgcga agccgccgat gcctttcatt ttgatgctgt
    10741 agaacagaat aaggatgaat acgcccagcg ccatcgacag ggtgatgttg acgtcagcag
    10801 acggcaccac gcgcgttgcc ggcagaccca gccaatgctc agcgatatac ggcagcaggt
    10861 cgataggcag taagtccatc aggttcataa ggaataccca gacgaaaatc gtcagggcca
    10921 gcggcgcaat cagcttgctt ttgccatggt acatgtcttt gacgctgcca tgcacaaagc
    10981 cgactatcag ctcaatcgcg gtctgaaact tgcctggcac gccgctggtc gcttttttag
    11041 caacgctacg gaacatcacc agaaacaaca gacccagcac caccgagaag aacatggagt
    11101 caatattgag cgtccagaag gtggctgggg ggttctgcgg atccaccagc gagaaagtac
    11161 gcaggtccag ctgaaggtta ttcagatggt gtcctatgta ttcctgcggc gtcatatttt
    11221 ctgaagccat gatgcctttt accctttgtt gttaattaca gccggcgcca gtatctgaac
    11281 caccagcacc aaaacccacg taacgatcag cggcaaaaac accgccttta aaaccgccaa
    11341 cgccaccacc agtaaaacca gcatcgctaa caccttgaag gcttcaccga aggcgaaagt
    11401 ccaggacacg cggcccttag caggtgtatg cgcctggtga cgccaggcaa atatcataaa
    11461 caacatatta ggcagtgcca ctgccaatcc cccacatact gcggagatgc cccagaaggg
    11521 gtctttgagg caaaacagca atccacttgc tattaccgcc agaaactgaa tgaacagaag
    11581 cttacgagca acgtttcgac tcacgagcga cacaggcatc acgtttttac tcctgctcac
    11641 ttcgaggtat gccgcgtgtc gtataaaacg ttctttaaga cttagagtca agcatcaaaa
    11701 agcggtcaaa ttatacggtg cgcccccgtg atttcaaaca ataagtagcc aaaaggtgaa
    11761 taaatgttta aatatttttc tctggcccgc atttttaact tttagctaaa gtgtgaacga
    11821 tcgtacaaaa ctgcaaatag cgcgaaaaca ctggcgataa agcgtgcacc agatcacaca
    11881 ttaaacatat tcatgcttac gcaattcatt tacgtgtcaa ttcatgcctt ttcatctttt
    11941 tgatatttaa gcgtaaaacc aggtactgtt ttaaaaatac cagcttacac cttaaaaacg
    12001 ccccattgac atttataata aaaatttaac aagcaaaagt gatttttcga ttcgattt
//
LOCUS       DAJVKX010000134        12017 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.134, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000134 DAJVKX010000000
VERSION     DAJVKX010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12017
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.134"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            552..1586
                     /gene="rhaT"
                     /locus_tag="OPY25_003694"
     CDS             552..1586
                     /gene="rhaT"
                     /locus_tag="OPY25_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HCS0929198.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKQVKQWSWETMWSVGGIV
                     SWLILPWTISALLLPDFWAYYGQFNLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLIHTEGGHMTLLGVFVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGALVNLGFCFIRLAKVQNLSIKADFSLARPLIISNILLSALGGLMWYLQFFFY
                     AWGHARIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWKNAGRRPVAVLSLGCVVIIIA
                     ANIVGLGMAS"
     gene            complement(1583..2431)
                     /gene="rhaR"
                     /locus_tag="OPY25_003695"
     CDS             complement(1583..2431)
                     /gene="rhaR"
                     /locus_tag="OPY25_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HCS0929199.1"
                     /translation="MANQLILLKKDFFTDEQQAVTVADRYPQDVFAEHTHEFCELVMV
                     WRGNGLHVLNERPYRITRGDLFYIRAEDKHSYTSVNDLVLQNIIYCPERLKLNVNWQA
                     MIPGFQGAQWHPHWRLGSMGMNQARQVINQLEHESNGRDPLANEMAELLFGQLVMTLK
                     RHRYATDDLPATSRETLLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTG
                     MTINQYLRQVRICHAQYLLQHSPLMVSEISMQCGFEDSNYFSVVFTRETGMTPSQWRH
                     LSNQSD"
     gene            complement(2584..3420)
                     /gene="rhaS"
                     /locus_tag="OPY25_003696"
     CDS             complement(2584..3420)
                     /gene="rhaS"
                     /locus_tag="OPY25_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HCS0929200.1"
                     /translation="MTVLHSVDFFPSGKAPVAIEPRLPQAAFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTISGGTVCFVRDHDRHLYEHTDNLCLTNVLWRSPDAFQFLAGLDQLL
                     PQEQDGYYPSHWRVNQSVLQQVRQLVGLMERAGDGMDAPAVANREILFMQLLVLLRRS
                     SLMEGATNNDAKLNQLMAWLEDHFAEEVCWEAVAEQFSLSLRTLHRQLKQHTGLTPQR
                     YLNRLRLIKARHLLRHSDHSVTEIAYRCGFGDSNHFSTLFRREFNWSPRDIRQGRDAI
                     IQ"
     gene            3708..5177
                     /gene="rhaB"
                     /locus_tag="OPY25_003697"
     CDS             3708..5177
                     /gene="rhaB"
                     /locus_tag="OPY25_003697"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HCS0929201.1"
                     /translation="MTFRHCVAVDLGASSGRVMLARYDSKHRTLTLREIHRFVNCLQK
                     TDGFDTWDIDSLEKDIRLGLKKVCNEGILIDSIGIDTWGVDYVLLDKQGQRVGLPVSY
                     RDNRTTGIMPQALVQIGKSEIYRRSGIQFLPFNTIYQLRALTKQQPELTAQVAHALLM
                     PDYFSYRLTGEMNWEYTNATTTQLVNINTDDWDDTLLAWTGAKKSWFGRPSHPGNVIG
                     DWICPQGNRIPVVAVASHDTASAVIASPLANKHSAYLSSGTWSLMGFESKKPYTTDEA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLKERRITDLPVLIAQTEALPACRFLINP
                     NDDRFINPDDMRAEIQAACRETDQPVPVSDAELARCIFDSLALLYADILHELANLRGE
                     KFTQLHIVGGGCQNALLNQLCANACGIRVMAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSANYDLTTYIPNPDSEIARHVAQFQPKRQTKELCA"
     gene            5174..6433
                     /locus_tag="OPY25_003698"
     CDS             5174..6433
                     /locus_tag="OPY25_003698"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HCS0929202.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VAGFENPEGSLTGGIQSTGNYPGKARNATELRADLEQALRLIPGPKRLNLHAIYLESD
                     TPVARDQIKPEHFKNWVEWAKANRLGLDFNPTCFSHPLSADGFTLSHPDAKIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLEALDEVISEKFDP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHNLFDRVHIGLDFFDASINR
                     VAAWVIGTRNMKKALLRALLEPTDQLRQLEASGDYTARLAMLEEQKSLPWQAVWEMYC
                     QRHDTPAGSQWLDSVRTYEKEILSKRS"
     gene            6491..7317
                     /gene="rhaD"
                     /locus_tag="OPY25_003699"
                     /pseudo
     CDS             6491..7317
                     /gene="rhaD"
                     /locus_tag="OPY25_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462926.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
     gene            7444..8592
                     /gene="fucO"
                     /locus_tag="OPY25_003700"
     CDS             7444..8592
                     /gene="fucO"
                     /locus_tag="OPY25_003700"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HCS0929203.1"
                     /translation="MSFMLALPKISLHGAGAIADMVNLVANKQWGKALIVTDGQLVKL
                     GLLDSLFSALDEHQMSYHLFDEVFPNPTEELVQKGFAAYQSAECDYIIAFGGGSPIDT
                     AKAVKILTANPGPSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSARKVKE
                     VIIDPNIIPDIAVDDASVMLEIPASVTAATGMDALTHAVEAYVSVGAHPLTDANALEA
                     IRLINVWLPKAVDDGHNLEAREQMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPH
                     GVCNAILLPIVENFNRPNAVARFARIAQAMGVETRGMSDEVASQEAINAIRTLSKRVG
                     IPEGFSKLGVTKEDIEGWLDKALADPCAPCNPRTASRDEVRELYLEAL"
     gene            8589..8903
                     /gene="rhaM"
                     /locus_tag="OPY25_003701"
     CDS             8589..8903
                     /gene="rhaM"
                     /locus_tag="OPY25_003701"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HCS0929204.1"
                     /translation="MIRKAFVMQVNADAHEEYQRRHNPIWPELEAVLKSHGAHHYAIY
                     LDQERNLLFATVEIESEERWNAVASTDVCQRWWKHMRDVMPANPDNSPVSAELKEVFY
                     LQ"
     gene            complement(8992..9540)
                     /locus_tag="OPY25_003702"
     CDS             complement(8992..9540)
                     /locus_tag="OPY25_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004855902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929205.1"
                     /translation="MTQPISVIARSLVRERQQTGLSLAEIARRAGIAKSTLSQLEAGN
                     GNPSLETLWSLCVALDIPFARLLEPQVQKTQVIRRGEGTKVVAEQAHYQAILLAACPP
                     GARRDIYLLLTQPGADRISHPHPPGSVEHIIVTQGKALVGLTEAPEELAEGDYICYPG
                     DQAHIFKALEPDTQAILVAEQN"
     gene            9641..10300
                     /locus_tag="OPY25_003703"
     CDS             9641..10300
                     /locus_tag="OPY25_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCS0929206.1"
                     /translation="MKHYFSCLKGDTIKAIFLVCLAVGVVGMSYGSLAMAYGFPLWVP
                     FVLSIFVLAGASEFMFIGIVASGGNPLAAAAAGLLVNARHVPFGVTVRDLVGTRAASF
                     FGCHIMNDESVVFGLSQKTPEQRKAAYWLCGLGVALFWPIGTLIGAGVGKLLPAPETI
                     GLDAVFPAILLALVIPAFKNRTTLIRGCSGAALSLAAVPFVAAGLPVLLSLLGLLARK
                     K"
     gene            10300..10623
                     /locus_tag="OPY25_003704"
                     /pseudo
     CDS             10300..10623
                     /locus_tag="OPY25_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462921.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
     gene            complement(10966..>12017)
                     /locus_tag="OPY25_003705"
     CDS             complement(10966..>12017)
                     /locus_tag="OPY25_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462920.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3829 domain-containing protein"
                     /protein_id="HCS0929207.1"
                     /translation="GATGCDDNNVKTEATPAASSQPATPAPSQTPETQSGESPAQPPA
                     AKPETATQPPAAKPETPAQPEVDAEEVYSEKMDVYIDCFNKLQLPVQHSLARYADWVK
                     DFKKGPTGKESLVYGIYGITESYITNCQKEMKQVAALTPLLEPIDGVAVSYIDSAAAL
                     GNTINEMEKYYTQENYKDDGFAKGKALHQTLLKNIEDFKPISEKYHEAIQEINDKRQL
                     TQLKKIEEAEGKTFNYYSLAVMISAKQINKVISADTFDAEAMMKKVAELETMIAQLKE
                     VNTDGRNSSFISSAADYQLQAKKYIRRIRDNVEYSDFEKKRVQDPATGWMVADSYPAS
                     LRSYNEMVDDYNRLR"
BASE COUNT         2794 a         3233 c         3105 g         2885 t
ORIGIN      
        1 acaatatagg caaagatctt taatttaaaa ttgggataat gttcaaaaag caaaataaaa
       61 taaatgaaat ttatattcgt catataaaat aaaaatcaaa actccatcaa caacgccaat
      121 atagggattt ccttatattt atatttcatt gattcctaac gttaatttca atatatttaa
      181 attgtaaata caaataaaac aactaaataa ttactgtata actacccttt tatcaaacgg
      241 taagtcagac tattcccatt atgtgatctc acgcagcgtt ttctttgcat tactgccagc
      301 taagtcgttt cgtgtcgtta tgatgaaggt attttagaaa acaaatatta cccactgatt
      361 taaataacat ccagacggtc acgatgcgct ccgacttttt taaaacgtga agttaatcac
      421 ttcattaacg tgctgattgc cagaatacac ccaacggcgg caatcgttat aaggttacca
      481 ggctgcgtaa tttttaaact catgcaaacg gaaggggtat cccgtccata aaaaataatg
      541 aggaacatgt catgagtaac gcgattacga tgggtatttt ctggcatctg ataggggcgg
      601 ccagtgcagc ctgcttctat gccccgttca agcaagtgaa acagtggtca tgggaaacca
      661 tgtggtcagt gggcggcatc gtctcatggc ttattctgcc gtggacaatt agcgctctgt
      721 tactgcctga tttctgggcc tattatgggc agtttaacct ctccaccctt ttaccggttt
      781 ttctgttcgg cgccatgtgg ggcatcggca atattaacta cggcctgacc atgcgttatc
      841 tcggcatgtc gatgggtatc ggcatcgcta tcggcattac gcttatcgtc ggcacgctga
      901 tgacgcctat catcaacggt aacttcgatg tattaatcca taccgaaggg ggacacatga
      961 cgctacttgg cgtttttgtc gcgctgatcg gcgtcgggat tgtgacgcgc gccggacagt
     1021 taaaagaacg caaaatgggc attaaagcgg aggagttcaa tctgaagaaa gggcttctgc
     1081 tggcagtgat gtgcggtatt ttctcggcgg ggatgtcttt tgccatgaac gccgcgaaac
     1141 cgatgcatga agctgctgcc gcgcttggcg ttgacccgct ctatgtcgcg ctgccgagtt
     1201 acgtggtgat tatgggcggc ggcgcgctgg tgaacctcgg tttctgtttt atccgcctgg
     1261 caaaagtgca aaatctgtcg ataaaagccg acttctcgct ggcaaggcca ttgattatca
     1321 gcaatattct gctgtccgcg cttggcggtc tgatgtggta tttgcagttc tttttctatg
     1381 cctggggtca cgcgcgcatt cccgcgcaat atgactacat gagctggatg ctgcacatga
     1441 gcttctatgt gctgtgcggg gggcttgtcg gtctggtgct aaaagagtgg aaaaatgctg
     1501 gccgccgtcc cgttgccgta ttaagcctcg gctgcgtggt aattattatc gcggcgaata
     1561 ttgtcggttt aggcatggcc agttaatcgc tttgattact gagatggcgc cattggctcg
     1621 gcgtcatccc ggtttcccgc gtgaacacca ctgaaaaata attactatct tcaaagccac
     1681 actgcatcga aatctcgcta accatcagcg ggctatgctg aagcagatac tgcgcgtggc
     1741 aaatacggac ctggcgtaaa tattgattaa tcgtcatccc ggtttgggcg cgaaactgct
     1801 gccgcagcac ccgctcgctg cattgttcct gctggcaaaa cgcatccagc gcaaagggac
     1861 actcaaggct attagccaaa gcggtaatta atttatccaa cagggtttct cgggaggttg
     1921 ccggaagatc gtcggtcgcg tagcgatgcc gttttaacgt cattaccagt tgaccaaaca
     1981 gcaattccgc catctcattc gccagcggat cgcgtccatt actctcatgt tcaagctggt
     2041 taatgacctg ccgcgcctga ttcattccca tactgcccag ccgccagtga ggatgccact
     2101 gcgctccctg aaagccggga atcatcgcct gccagtttac attgagtttc aaacgctccg
     2161 ggcagtaaat aatattttgc agcaccagat cgttaacgga agtataggag tgtttgtctt
     2221 cagcacgaat gtaaaacaga tcgccgcggg taattctgta tgggcgctca ttaagaacgt
     2281 gtaggccatt gccccgccag accatcacca gttcacaaaa ctcatgcgta tgttccgcaa
     2341 aaacatcctg tggatagcga tcggcaaccg taacggcctg ctgctcatca gtaaaaaaat
     2401 cttttttcaa aaggattaac tgatttgcca ccgcagcacc tcatgttgaa tgcttgccgg
     2461 ctggcgctac gcttattctg tctaccgctc gccgccgtag gccaggtaag gcgcagccgc
     2521 catccggtat taaagggtat aattatcagc atattggcga cgaaaacgtt gatagcgttc
     2581 gcgttactgg attatcgcat cgcgtccctg acggatatcc cgcggcgacc agttaaattc
     2641 tcggcgaaac agagtcgaaa agtggttact gtcgccaaaa ccgcagcggt acgcgatttc
     2701 tgtcacgcta tgatcgctat ggcgcaataa atgccgggct ttgatcaaac gcaggcgatt
     2761 aaggtaacgt tgcggcgtca gcccggtatg ctgtttaagc tgacgatgca gcgtacgtag
     2821 cgacagcgaa aactgttcag ctaccgcctc ccagcagacc tcctccgcaa aatggtcttc
     2881 cagccatgcc atcagttggt tgagtttggc gtcgttattg gtcgcgcctt ccatcaggct
     2941 actgcggcgt aacaacacca gtagttgcat aaacaaaatt tcgcgattcg ccacggcagg
     3001 cgcatccatg ccgtctccgg cgcgctccat cagaccgacc aactggcgca cctgctgcaa
     3061 cacactctga ttcacccgcc agtgagaagg atagtaacca tcctgctcct gcggcagcaa
     3121 ttgatccaac cccgccagga actggaaggc gtccggtgaa cgccacagta cattcgtcag
     3181 gcataggttg tcggtatgtt catataaatg ccggtcgtga tcgcgaacaa aacacacggt
     3241 accgccgctg atggtatacg gctgcccgtt gaatacatga atgcccgtac cgtgttccac
     3301 aatcacgatt tcatgaaaat catgatgatg ttcagggaaa gcggcttgcg gcagacgagg
     3361 ttcaatcgcc acgggcgctt tacctgatgg aaaaaaatcc acgctatgca gtacggtcat
     3421 ggttgcttcc tcctgaattc aacatgtccg aatagtaatt aagggttatc ggcctcacct
     3481 taaatttttg acgctaaagc gcgcaaacat ggtctttttt tcaagaaaag gcgggaaaaa
     3541 gcgggaaatg cggacgacat cacaccggcc tattagtaga aactgtgaac gctatcacgt
     3601 tcatctttgc cttgttgcca gcggctcatt ttcctgtcag taacgagaag gtaggtcttt
     3661 gagggctttt ttagactgtg cgcaatgact ctaagaagga cctgattatg acttttcgcc
     3721 attgtgtcgc ggttgatctc ggcgcatcca gcgggcgcgt gatgctggcg cgttacgaca
     3781 gcaaacaccg taccctgacg ctacgtgaaa ttcaccgttt tgtgaactgc ctacaaaaaa
     3841 cagacgggtt tgacacctgg gacatcgaca gtctggaaaa ggatatccgt cttggtctga
     3901 agaaagtctg caatgaaggc attcttatcg acagcatcgg catcgacacc tggggcgtcg
     3961 attatgtcct gctggataaa caaggtcagc gtgtcggcct gccggtctcc taccgcgata
     4021 accgtaccac gggcatcatg ccgcaagcgc tggtccagat cggcaaaagc gaaatctatc
     4081 gccgcagcgg gattcagttt ctgccgttta acaccatcta tcagctacgc gcgctgacga
     4141 aacaacagcc tgagttaacg gcgcaggtcg ctcatgcgct gctgatgcct gattatttca
     4201 gctaccgcct gaccggtgaa atgaactggg agtacaccaa cgccacgacc acccagttgg
     4261 tcaatatcaa taccgatgac tgggacgata ccctgctggc gtggaccggc gcgaaaaaga
     4321 gctggttcgg ccgcccctcg caccctggca atgttatcgg cgactggatt tgcccgcagg
     4381 gcaaccgtat tccggtggta gccgtcgcca gccacgatac cgccagcgcc gttattgcct
     4441 ctccgctggc aaataaacat agcgcttacc tgtcttcagg cacctggtcg ttgatgggtt
     4501 ttgaaagcaa aaaaccctac accactgatg aggcgctggc cgccaatatc accaacgaag
     4561 gcggcgcgga agggcgttat cgggtactga aaaacattat gggtttgtgg ctgctccagc
     4621 gcgtgctgaa agaacggcgc attaccgatc tgcctgtgct tatcgcccaa acagaagcgc
     4681 tgccggcctg ccgtttcctg attaacccga atgacgatcg ctttatcaat cctgacgata
     4741 tgcgcgccga aatccaagcc gcctgtcgcg agaccgacca gcccgttccc gtcagcgatg
     4801 ccgaactggc gcgctgcatt ttcgacagtc tggcgctgtt gtatgccgac attctgcacg
     4861 aactggcaaa tctgcgcggc gaaaaattta cccaactgca tattgtcggc ggcggatgcc
     4921 aaaacgcgct actcaaccag ttgtgcgcca atgcatgtgg cattcgcgtg atggccgggc
     4981 cggttgaagc ctccaccctt ggcaatattg gtattcagct tatgaccctc gacgaattaa
     5041 acaacgtcga tgatttccgt caggtcgtca gcgctaacta cgacctgaca acctatatcc
     5101 ctaatcctga tagtgaaatt gcccgccacg ttgcgcagtt tcaacccaaa cgacagacaa
     5161 aggagctttg cgcatgacca ctcaactgga acaagcctgg gaactggcaa aacaacgttt
     5221 cgccgcagta ggtattgatg tcgaggaggc gctgcgccag ctcgatcgcc tgccggtttc
     5281 catgcactgc tggcagggcg acgatgttgc cggattcgag aacccggaag gttcgctgac
     5341 gggcggaatt caatcgaccg gcaactatcc gggcaaagcg cgtaacgcca ccgaactgcg
     5401 cgccgatctg gaacaggcgc tgcgtctgat cccaggcccc aaacgtctga acctgcatgc
     5461 gatctatctg gaatccgata cgccggttgc ccgcgaccaa atcaaaccgg agcattttaa
     5521 aaactgggtg gagtgggcga aagcgaaccg actggggctg gatttcaacc ccacctgttt
     5581 ttctcatcca ctgagcgctg acggttttac cctctctcat ccagacgcga aaattcgcca
     5641 gttctggatc gatcactgca aagccagccg ccgcgtctcg gcatactttg gtgagcagct
     5701 cggtacgccg tcggtgatga acatctggat tccggacggc atgaaagaca ttaccgtcga
     5761 ccgtttagcc ccgcgccagc gcctgctgga agcgctggat gaggtcatta gcgagaaatt
     5821 cgacccggcg caccacatcg acgccgttga gagcaaactg tttggcatcg gcgcggaaag
     5881 ctacaccgtc ggctccaatg agttctacat gggctacgcc accagccgtc agaccgcgct
     5941 gtgtctggat gcgggccact tccatcccac tgaagtgatt tccgacaaaa tttccgccgc
     6001 catgctctat gtgccacggc tgctgctgca cgtcagccgc ccggtacgct gggatagcga
     6061 ccacgtggtg ctcttggacg atgaaaccca ggcaattgcc agcgagatcg tccgtcataa
     6121 cctgttcgac cgtgtgcata tcggcctgga tttcttcgac gcctctatca accgtgtcgc
     6181 cgcgtgggtt atcggtaccc gcaacatgaa aaaagcgcta ctgcgcgctc tgctggaacc
     6241 cacagatcaa ctgcgtcagc ttgaggccag cggcgattac accgcgcgtc tggcgatgct
     6301 ggaagagcaa aaatctctgc cgtggcaggc cgtctgggaa atgtattgcc agcgtcacga
     6361 cacgccggct ggcagccagt ggctggacag cgttcgcacc tacgaaaaag agatcctgag
     6421 caaacgtagc tgacagcgac acctgatctg taggccggat aaccttcggg caataaatgg
     6481 gaacacgaat atgcaaaata ttaccgattc ctggtttgtc cagggcatga ttaaagccac
     6541 gtctgatgcg tggctgaaag ggtgggacga gcgtaatggt ggcaacctga cgctgcgcct
     6601 ggatgaagca gacatcgcgc catttagcgc cgatttccac gaaaaaccac gctatatcac
     6661 gctaagtcaa ctcatgccgc tgctggcgaa tacaccgttt atcgttaccg gctccggcaa
     6721 attcttccgc aacgttcagc tcgatccggc agccaattta ggcgtggtca aaatcgacag
     6781 cgacggcgct ggctaccaca ttctgtgggg cttaacccac gacgcggtac ccacctctga
     6841 actcccggcg cacttcctct cccactgcga acgcatcaaa gccacccacg gcaaagaccg
     6901 cgtcattatg cattgccatg cgactaacct gatcgccctc acctacgtac tggaaaacaa
     6961 cactgcgctg atcacccgca aactgtggga aggcagcacc gaatgcctgg tggtattccc
     7021 ggacggtgtc ggcattctgc cgtggatggt gccaggcccg atgaaatcgg ccaagccacc
     7081 gcgcaagaaa tgcagaaaca ttcgctggta ctgtggccgt tccacggcgt gttcggaagc
     7141 ggacctacgc tgaatgaaac cttcggtttg atagataccg cagagaaatc cgctgaggta
     7201 ttagtcaaaa tctattcgat gggcggtatg aagcagacca tcacgcgcga agaactggtc
     7261 gcactcggca aacgatttgg cgtgacaccg ctggccagcg ccgtagagct gtactgatac
     7321 ctcccaactc aacgccggat gcggctttgc cttatccggc ctacaggtcg gtgcgcattt
     7381 taccgtaggc ccgataagcg tagcgccatc gggcaacagg gaattttttt aaggagaata
     7441 gtgatgagct ttatgttggc actgccaaaa attagcctgc atggcgctgg agcgattgcc
     7501 gatatggtga acctcgtggc gaataagcaa tggggcaaag cgctgatcgt taccgatggt
     7561 caactggtaa agctgggcct gctggatagc ctgtttagcg cactggatga acatcaaatg
     7621 tcttaccacc tgtttgatga ggtgttccca aacccgacag aagagctggt gcagaaaggt
     7681 tttgcggcgt atcagagcgc agaatgtgac tacattatcg ccttcggcgg cggcagcccg
     7741 atcgataccg caaaagcggt gaaaattctg accgccaacc caggtccatc taccgcctac
     7801 tccggcgtcg gcaaagtgaa aaacgccggc gtaccgctgg tagcgattaa cactacggca
     7861 ggtaccgcgg cagagatgac cagcaacgcg gtgattatcg actctgcccg taaggtcaaa
     7921 gaggtgatca tcgacccgaa tatcatcccg gatattgccg tggatgacgc cagcgtcatg
     7981 ctggaaatcc cggcgtctgt gaccgccgca accggcatgg atgccctgac ccatgcggtg
     8041 gaagcctatg tctccgttgg cgcgcatccg ctcaccgacg ctaacgcgct ggaagcgatt
     8101 cgcttaatca atgtgtggct accgaaagcg gttgacgatg gtcataacct cgaagcccgt
     8161 gagcaaatgg cattcggcca gtacctggcg ggtatggcgt tcaacagcgc cggtttgggg
     8221 ctggttcacg cgctggcgca ccagccgggc gcaacccaca acctgccgca cggcgtctgc
     8281 aacgctatcc tgctgccaat tgtcgagaac tttaaccgtc cgaacgccgt cgcgcgtttt
     8341 gcccgcatcg cacaggcgat gggcgtggag acgcgcggta tgtctgacga agtcgcaagt
     8401 caggaagcga ttaacgctat ccgtacgctg agcaaacgcg tcggcattcc agaaggtttc
     8461 agcaagctgg gcgtcacaaa agaagatatc gaaggctggc tggataaagc cctcgccgac
     8521 ccgtgcgcgc cgtgtaaccc gcgcaccgcc agccgcgatg aagttcgcga gctgtacctg
     8581 gaggcgttat gatccgcaaa gcctttgtga tgcaggtaaa tgccgacgcg cacgaggagt
     8641 atcagcgtcg tcataaccca atctggccgg agctggaagc cgtattaaaa tctcacggcg
     8701 cgcatcacta cgcgatttat ctcgatcagg agcgcaatct gctgttcgcc accgttgaga
     8761 ttgaatccga ggagcgctgg aacgccgttg ccagcaccga cgtttgccag cgttggtgga
     8821 aacatatgcg tgacgttatg cccgcgaatc cggataacag cccggtcagc gcagagctaa
     8881 aagaggtgtt ctatctgcag taagtcgtgt gcccgatggc gcaagcttac cgggcctacg
     8941 gttttatttt ttgtcggccg gataaggcgg ttacgccgcc atccggcaat ttcaattctg
     9001 ctccgctacc aggatagcct gagtatccgg ttccagcgct ttaaagatat gcgcctggtc
     9061 gccgggataa caaatgtaat cgccctccgc cagctcttcc ggcgcctcgg ttaagccgac
     9121 gagggctttt ccctgcgtaa caataatatg ttccaccgac cccggcggat gcggatgaga
     9181 gatccggtcg gcccccggct gcgtcaacag cagatagata tcacgccgcg cgccgggcgg
     9241 acacgccgcc agtaatatcg cctgataatg cgcctgctcc gccacgactt tggtgccttc
     9301 tccgcggcga atcacctgcg ttttttgtac ctgcggctcc agcagcctgg caaagggaat
     9361 gtcgagcgcg acgcatagcg accatagcgt ctccaggctg gggttgccgt tccctgcttc
     9421 cagttgtgaa agcgtagatt tagcgatgcc tgcgcgccgc gcaatctccg ccagcgacag
     9481 tccggtttgc tggcgttcgc gtaccaggct tctggcaatg acgctaatag gttgtgtcat
     9541 aaagcatcca acgttcacta taacgaacga aatgttcgtc ttgtaaagca aatctgttcc
     9601 gttcattata atgaaaattc gttcgatatg actaaagaag atgaaacact atttttcctg
     9661 tctcaaggga gacacgataa aagcgatatt tttagtgtgc ctggccgtgg gcgtcgtcgg
     9721 catgtcctat ggctcactgg cgatggccta cggtttccca ctgtgggtgc cgtttgtcct
     9781 ctctattttt gtgctggcgg gcgcgtccga atttatgttt atcggcattg ttgccagcgg
     9841 cggcaatccg ttagcggcgg cggcggcagg actactggtg aatgcgcgcc acgtgccgtt
     9901 tggcgtaacg gtgcgcgatt tggttggcac ccgcgccgcc agctttttcg gctgccatat
     9961 catgaatgat gagagcgtgg tgttcggcct gtcgcaaaaa acacccgaac aacgtaaagc
    10021 cgcctactgg ctatgcggtc tgggcgtcgc cctattctgg ccgattggca cactgattgg
    10081 cgcaggtgtc ggcaaactgc tcccggcccc agaaaccatc ggtctggacg ccgtattccc
    10141 ggcaatctta ctggcgctgg tgatcccggc gtttaaaaac cgcaccacat tgattcgtgg
    10201 ttgcagcggc gccgcgctgt cgcttgccgc cgttcccttt gtggctgccg gattgccggt
    10261 gttgctttcg ctgcttggcc tactggcgag gaaaaaataa tgggcaatat gacgctattt
    10321 attatcggta ttgctctttt atctacggga acctatttga tgcgcctcgg cggcgcgaaa
    10381 cttggcagcc gtctggcgct gtctgagcgt tcacaggcgc tgctctcgga tgcggcaacg
    10441 gtgctgctat tctccgtcgc gctggcgacc accttttacg aaggcgaaca ttttgccgga
    10501 atggcgcgcg ttcttggggt tggcttcgcc gtatttttag cctgacgtaa aatgccgctt
    10561 attgtggtga ttatcgccgc tgcagtggtg accgcgttat tacgaatggc gggtattaat
    10621 taacgtctta cagaacagtt ggacgtgaca ccctataagt gatgaaggct gggccgccct
    10681 atgctgaagt ggctcagaat tttcgcatca gggggataaa tgttttccat atgaatgccg
    10741 attctcaatt acactatcag agtaacttca acatcttgtg atagcttcag attactggtt
    10801 ttcctaatag ctctccttag ttaaggttta cgtcagctat ttttacggat attgcctgac
    10861 gaaatgcatg aacgaaaaaa gcgcctgatc ggcgctcttt attggtgtta tagcgtaact
    10921 ttataggcgc ttacgccagc ctgcacgcag ttaatgtgcc gtcactcaac gcaggcggtt
    10981 ataatcatcc accatctcgt tataacttct caacgacgcc ggataagaat ccgcaaccat
    11041 ccatcctgtt gcagggtcct gcacccgttt cttttcaaaa tcagaatact caacattgtc
    11101 tctgatgcga cgaatatatt ttttagcttg tagctgataa tcagccgcag agctgatgaa
    11161 agaagaatta cggccatcag tattcacttc tttcaattgc gcaatcattg tttccagttc
    11221 cgcgactttt ttcatcatcg cttcggcatc aaaggtatcg gcagaaataa ccttgttgat
    11281 ctgctttgcc gaaatcatga cagccagaga ataatagtta aatgttttac cttccgcttc
    11341 ttctattttc ttcaactgtg tcaattgccg cttgtcattt atttcctgaa tagcctcatg
    11401 atatttttcc gagataggtt taaaatcctc gatattcttc agtaatgtct gatgcagcgc
    11461 cttaccttta gcaaaaccat catctttata gttttcctgg gtataatatt tttccatttc
    11521 gttaatggta ttacccagcg cggcggcgct atcaatatag ctaacggcaa cgccatcaat
    11581 aggctcaagc aatggcgtta aggcggccac ctgtttcatc tctttctggc aattcgttat
    11641 gtaagactcc gtaataccat aaatgccata aaccaggctc tctttccctg tcggaccttt
    11701 tttaaagtct ttcacccaat ccgcgtaacg cgccagactg tgctgaacgg gcaattgaag
    11761 tttattaaaa caatcgatat agacatccat tttttcacta taaacttctt cagcgtcaac
    11821 ctccggctga gctggcgttt ctggcttcgc cgccgggggc tgagttgctg tttctggctt
    11881 cgctgctggg ggctgcgctg gactttcgcc agattgcgtt tccggcgtct gagaaggcgc
    11941 tggcgtcgca ggctgactgc tggcggccgg cgtcgcctcg gttttaacat tattgtcatc
    12001 acatcctgtt gcgccca
//
LOCUS       DAJVKX010000135        11901 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.135, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000135 DAJVKX010000000
VERSION     DAJVKX010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11901
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.135"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..1796
                     /locus_tag="OPY25_003706"
     CDS             <1..1796
                     /locus_tag="OPY25_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCS0929208.1"
                     /translation="FDQYRKTILAGAVALTCGLTAASTFAAGFQPAQPAGKLGAVVVD
                     PYGNAPLTALVELDSHIISDVKVTVHGKGEKGVPVTYTVGKESLETYDGIPIFGLYQK
                     FANNVTVEYKENGKAMKDDYVVQTSAIVNHYMDNRSISDLQQTKVIKVAPGFEDRLYL
                     VNTHTFTPQGAEFHWHGEKDKNAGILDAGPAGGALPFDIAPYTFVVDTQGEYRWWLDQ
                     DTFYNGHDMNINKRGYLMGIRETPRGTFTAVQGQHWYEFDMMGQILADHKLPRGFLDA
                     SHESIETVNGTVLLRVGKRDYRKEDGIHVHTIRDQIIEVDKSGRVVDVWDLTKILDPM
                     RDALLGALDAGAVCVNVDLAHAGQQAKLEPDTPYGDALGVGAGRNWAHVNSIAYDAKD
                     DSIILSSRHQGIVKIGRDKQVKWILAPSKGWNKQLASKLLKPVDDHGKPLTCDENGKC
                     KDTDFDFTYTQHTAWLSSKGTLTVFDNGDGRGLEQPALPTMKYSRFVEYKIDEKKGTV
                     QQVWEYGKERGYDFYSPITSVVEYQKDRDTMFGFGGSINLFDVGKPTVGKLNEIDYKT
                     KEVKVEIDVLSDKPNQTHYRALLVHPTQMFK"
     gene            1816..2487
                     /locus_tag="OPY25_003707"
     CDS             1816..2487
                     /locus_tag="OPY25_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HCS0929209.1"
                     /translation="MSSKWITSLFKSVVLTAALVTPFAASAFTEGTDYMVLEKPIPNA
                     DKTLIKVFSYACPFCYKYDKAVTGPVSDKVADLVTFTPFHLETKGEYGKQASEVFAVL
                     IAKDKAAGISLFDAKSQFKKAKFAWYTAYHDKKERWSDGKDPAAFIKTGLDAAGMSQA
                     DFEAALKDPAVQETLEKWKAAYDVAKIQGVPAYVVNGKYLIYTKNIKSIDSMAELVRE
                     LATKK"
     gene            2502..3179
                     /gene="dsbI"
                     /locus_tag="OPY25_003708"
     CDS             2502..3179
                     /gene="dsbI"
                     /locus_tag="OPY25_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide oxidoreductase DsbI"
                     /protein_id="HCS0929210.1"
                     /translation="MDFIKGLWRDLRARPVDTLVRWQEQRFLWLLMAIAMGGLIILAH
                     SFFQIYLYMAPCEQCVYIRYAMFVMVIGGVIAAINPKNIVLKLIGCIAAFYGSIMGIK
                     FSIKLNGIHHAVHNADPDSLFGVQGCSTDPTFPFNLPLAEWAPEWFKPTGDCGYDAPI
                     VPDGVTLSSVQQWFVDLYQQSEGWYLLPPWHFMNMAQACMLAFGLCLILLLVMSGAWA
                     LKLARGK"
     gene            complement(3350..4003)
                     /gene="ribB"
                     /locus_tag="OPY25_003709"
     CDS             complement(3350..4003)
                     /gene="ribB"
                     /locus_tag="OPY25_003709"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HCS0929211.1"
                     /translation="MNQTLLSSFGTPFERVELALDALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRVTTVRAAIKDGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIAFAGQHNMAVVTIEDLVAYRQAHERKAS"
     regulatory      complement(4109..4307)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            4440..4736
                     /gene="ubiK"
                     /locus_tag="OPY25_003710"
     CDS             4440..4736
                     /gene="ubiK"
                     /locus_tag="OPY25_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HCS0929212.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDIEKKIRQTLQSQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRLSELEARDKPEEVKPAPAIPPVDPQE"
     gene            complement(4811..5020)
                     /gene="glgS"
                     /locus_tag="OPY25_003711"
     CDS             complement(4811..5020)
                     /gene="glgS"
                     /locus_tag="OPY25_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HCS0929213.1"
                     /translation="MLMNNNNVYSLNNFDFLARSFARMQAEGRPVDIQAVTGNMDEEH
                     RDWFCKRYALYCQQATQAKKLELEH"
     gene            5278..5898
                     /locus_tag="OPY25_003712"
     CDS             5278..5898
                     /locus_tag="OPY25_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HCS0929214.1"
                     /translation="MTLFAEYNSPYLFAIAFVFFIGVLEMISLIFGHFLSGALDAHLD
                     HYDALSSGPAGQALHYLNIGRVPALVVLCLLAGYFGLFGILIQHGGIMLWQAPLSNLL
                     LVPLSIVLSVFAVHYSEKILAPWLPRDESSALREEEFIGGMAIITGHAAVAGTPCEGK
                     FTDKFGQIHYLLLEPEKGKEFKKGDKVLIVCRLSATRYLAERTFYV"
     gene            5917..7596
                     /locus_tag="OPY25_003713"
     CDS             5917..7596
                     /locus_tag="OPY25_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCS0929215.1"
                     /translation="MDDVFGILPSWMFTAIVAVIVLLIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRATVDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATSAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALERKLEIEQQEAFMTLEQEQQVKTRTAEQNAKIAAFEA
                     ERHREAEQTRILAERQIQETEIEREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANDALADAVRAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAELQAAAIIELAEAARKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQSLPAVIEKSVEPMKSIDGIKIIQVDGLNRGATAGDVAAGGANGGNLAEQAL
                     SAALTYRTQAPLIDSLLNEIGIAGGSLKALTTPLVSSATDEINREATIKEQ"
     gene            7837..7896
                     /locus_tag="OPY25_003714"
     CDS             7837..7896
                     /locus_tag="OPY25_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HCS0929216.1"
                     /translation="MMHQVIILIVLLLISFPAY"
     gene            complement(8056..9489)
                     /gene="hldE"
                     /locus_tag="OPY25_003715"
     CDS             complement(8056..9489)
                     /gene="hldE"
                     /locus_tag="OPY25_003715"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HCS0929217.1"
                     /translation="MKVNLPAFERAGVMVVGDVMLDRYWYGPTCRISPEAPVPVVKVN
                     TVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALGSIGALVLSDYAKGALTSV
                     QTMISLARQAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMK
                     LIADYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNTLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELRQAVAS
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGESRPVNP
                     LEQRMIVLGALESVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSEEVWANG
                     GEVMVLNFEDGCSTTNIIKKIQTESEK"
     gene            complement(9537..>11901)
                     /gene="glnE"
                     /locus_tag="OPY25_003716"
     CDS             complement(9537..>11901)
                     /gene="glnE"
                     /locus_tag="OPY25_003716"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HCS0929218.1"
                     /translation="GKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQ
                     RLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKAR
                     LMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGA
                     GGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLR
                     RLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGELTDHMANVRRVFNELI
                     GDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQVLTLIADFRKELDK
                     RPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGA
                     LKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEED
                     EEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWTQMVA
                     RYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGEREIDGR
                     QFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWE
                     HQALVRARVVYGDPQLTSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRD
                     RFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQA
                     LTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV"
BASE COUNT         2933 a         3265 c         3005 g         2698 t
ORIGIN      
        1 tgtttgacca ataccggaaa acaatacttg ccggcgccgt cgcactgaca tgcggactca
       61 ccgcagccag tacgtttgcc gcaggttttc aaccggcgca gcccgcaggg aaattaggcg
      121 cagtcgttgt cgatccttac ggtaatgccc ctctcaccgc actggtggaa ttagatagcc
      181 atattatttc agacgttaaa gttactgtac atggcaaagg ggaaaaaggc gttcccgtta
      241 cttataccgt tgggaaagag tctttagaaa cctatgacgg tattcctatt tttggccttt
      301 atcagaaatt tgccaacaac gtcacggtag aatataaaga aaacggcaaa gccatgaagg
      361 atgactatgt ggtgcagacg tccgccatcg tcaaccatta tatggataac cgttctattt
      421 cagatctcca gcaaacgaaa gttattaaag ttgcgccagg atttgaagat cgcctttatc
      481 tggtaaatac ccataccttt acgccgcagg gcgctgaatt tcactggcac ggcgaaaaag
      541 ataaaaatgc gggcattctt gatgccggcc cggcgggcgg ggctttgcct ttcgatatcg
      601 ccccttatac gtttgtggtc gacacccagg gtgaataccg ctggtggctg gatcaagata
      661 ccttctacaa cggccacgat atgaatatca acaaacgtgg ctacctgatg gggattcgtg
      721 aaacgcctcg cggcaccttt accgcggtgc agggccaaca ctggtacgag tttgacatga
      781 tggggcaaat tcttgccgat cataaactgc cgcgcgggtt cctggacgca tctcatgaat
      841 ccatcgaaac cgtgaacggt accgtactgc tgcgcgtcgg caaacgcgat taccgcaaag
      901 aagacggcat acatgttcat actattcgtg accaaatcat tgaggttgat aagtctggcc
      961 gcgtagtaga cgtttgggat ttaaccaaaa tcctcgaccc tatgcgtgat gcgctgctcg
     1021 gcgcgctgga tgcgggcgca gtatgcgtga acgtcgatct ggcccatgcc ggacagcagg
     1081 cgaaactcga accggatacg ccgtatggcg atgcgcttgg cgttggtgcc ggtcgtaact
     1141 gggcgcacgt caactctatc gcttatgacg cgaaagacga ctccatcatc ctttcttccc
     1201 gccatcaggg tattgtaaaa attggtcgcg ataagcaggt gaaatggata ctggcaccgt
     1261 ctaaaggctg gaataagcag ctagccagta aattgctgaa accggtagac gatcatggta
     1321 agccgttgac ctgtgacgaa aacggcaagt gtaaggacac cgatttcgat ttcacctata
     1381 cccaacatac ggcatggctt tccagcaaag gtacgttaac ggtctttgat aacggtgatg
     1441 gtcgcggcct ggagcaaccg gctctaccga ccatgaaata ttcccgtttt gtcgaatata
     1501 agatcgatga gaagaaaggc accgtacaac aagtttggga atacggtaaa gaacgtggat
     1561 atgatttcta tagtcctatt acctcggttg ttgaatatca aaaagaccgc gacaccatgt
     1621 tcggctttgg cggttctatt aacctgttcg acgttggtaa accaacagtc ggcaaactga
     1681 atgagattga ctataaaacg aaagaagtga aagttgaaat tgatgtgctg tcggataaac
     1741 ccaaccagac tcactatcgt gcgttactgg tacatccaac acaaatgttt aaataaatca
     1801 cgggaaggaa ttaatatgtc atctaaatgg attacctctt tatttaaaag cgtagtatta
     1861 accgcggcat tggtcactcc ttttgcggca tcggctttta ccgagggcac agattatatg
     1921 gttctggaga aaccaattcc taatgcggat aaaacgctga ttaaggtatt tagctacgcc
     1981 tgccctttct gctacaaata tgacaaagcc gtaacaggtc cggtttctga taaagtcgcc
     2041 gatctcgtta cgttcacccc gttccacctg gaaacaaaag gcgaatatgg caaacaggcc
     2101 agcgaagtat ttgcagtcct gatcgccaaa gataaagctg ccgggatttc gttatttgat
     2161 gctaaatcac aattcaaaaa agcgaagttc gcctggtata cggcttacca tgataagaaa
     2221 gagcgctggt cagatgggaa agatccggcg gcatttatta aaaccgggct ggacgccgca
     2281 ggcatgagcc aggctgattt tgaagcggcg ctgaaagatc ctgccgttca ggagactctg
     2341 gaaaaatgga aagcagccta tgacgttgcc aaaattcagg gtgttccggc ttacgtcgtc
     2401 aacggcaagt accttatcta caccaaaaac atcaaatcca tcgattctat ggctgaactc
     2461 gttcgggaac tggccactaa aaaataagca gggaaacgat tatggatttt attaagggat
     2521 tatggcgaga cctacgcgca agaccagtgg atacgctggt gagatggcag gaacagcgct
     2581 ttctgtggct gttaatggcc atcgcgatgg gaggattaat tatcctggcg cactcgttct
     2641 tccaaatcta cctctacatg gcaccgtgcg agcagtgtgt ttacatccgt tacgcgatgt
     2701 ttgtgatggt aattggcggg gtgattgcgg caataaatcc caaaaatatt gtgctgaagc
     2761 tgattggctg catcgcggcg ttttatggca gcattatggg cattaagttt tctattaagc
     2821 ttaatggtat ccatcatgcg gtacataatg cggaccccga ttcacttttt ggcgtgcaag
     2881 gatgttcgac tgacccgacc tttcctttca acttaccgtt ggcggaatgg gcaccggagt
     2941 ggtttaaacc taccggagac tgcggttatg acgcgcctat cgtccctgat ggcgtgacgc
     3001 tcagtagcgt acagcagtgg tttgtcgatc tctaccagca gtccgaaggc tggtatctgc
     3061 ttccgccctg gcactttatg aacatggcgc aggcatgtat gttggccttt gggttgtgcc
     3121 tgattctgct gctggtgatg agcggcgcct gggcattgaa actggccaga ggcaaataac
     3181 ctgaatagat aaaccaaagc agaggtctgc attcaggcct ctgcttttct cacaataatt
     3241 ttaccattca gcttattcgt cgttctttga aactgaacaa tatggcaccg aaggaataca
     3301 aaaaagccga tgagatgtca tcggcttttt tcaaccatga tccgttcgat cagctggctt
     3361 tgcgctcatg cgcctggcgg taagccacca gatcttcaat cgtgaccacc gccatattat
     3421 gctggcctgc aaacgcgata cactccggcg cgcgcgccat cgtcccatcg tcgttagtca
     3481 actcgcacag tacacctgca ggtttaaaac cggccagcgt catcagatcg atggtcgcct
     3541 ccgtatgacc gccgcgcgtc agcacgccgc ccgcctgagc gcgcagtggg aaaacgtgcc
     3601 ccggacggtt aagatcggac ggttttgcgc catccttaat tgccgcacgc accgtagtga
     3661 cacggtcagc ggcggaaacg ccggtggtca cgccttctgc ggcttcaatg gtcacggtaa
     3721 aaccggtgcc gtaggcgctg gtgttgtttt ccaccatcat tggcaaatcg agctgcttac
     3781 ggcgatcttc agtaatacac aggcaaacaa taccgctacc gtgacgaatg gttaacgcca
     3841 tctgttctac ggtcattgtc tctgcgggga aaatcatatc gccttcgttt tcacgatctt
     3901 catcatcaag caccatcaca ccgcgtcctt cacgcagcgc atccagtgca agttcaacac
     3961 gttcaaaagg cgtaccaaaa gaggaaagta gcgtctgatt catggtaaaa aaacctcatt
     4021 aacattatgg ttaccagaat cagggcagtc ttaggagtgc cgacaagcgg caaaaaaata
     4081 acgtgagcgg gtccatgccc gactggatcg ttaccctctc ccatccggac tttaaccgtc
     4141 ggccccggaa ttacaccgga tctgctgacc ttttcgctat ggcaaaaagc gctcgcgggc
     4201 tttcaacctg ctctccgcgt tccgtcacgg cgcaccgtga tgagaaatgc gttaaacatc
     4261 gctgatttac cgccggtggg gaatttcgcc ccgccctgag aataagcggg ttaactataa
     4321 cgctattgat taccttcatc aacgccttta ctccgtatga catcacacaa ttctggttta
     4381 tggcgtccac atatcgcact acaataagag ctaacactta ccagttcagg gaaaccacaa
     4441 tgattgaccc gaaaaaaatt gagcaaatcg cacgccaggt tcatgagtca atgccgaaag
     4501 gtattcgcga gttcggggaa gatatcgaga aaaaaatccg tcaaacgctg caatctcagc
     4561 tgacgcgtct cgatctggtg agccgcgaag agtttgatgt ccagactcag gtcttgctgc
     4621 gcacccggga aaaactggcg ctgctggagc aacgcctcag cgaactggaa gctcgcgaca
     4681 agcctgaaga agtaaaacct gcgcccgcca ttccgccagt cgatccacaa gagtaaaaac
     4741 gtgaacgggc ctgacggccc gctcatataa gatctgaata atgccctgcg cctgtataag
     4801 ggagcctgca ttagtgttct aattctaact ttttcgcctg agtcgcctgc tggcagtaaa
     4861 gcgcgtaacg cttgcaaaac cagtcgcggt gctcctcgtc catattgccg gttaccgcct
     4921 ggatatcaac aggacgcccc tccgcctgca ttctggcaaa gctgcgcgcc agaaaatcga
     4981 aattatttaa tgaatagacg ttattgttgt tcatcagcat accctccagt tattgaattc
     5041 tgttaaggct atatgctttt tctaatttca gtatttccct atatgtacgg cggttttata
     5101 cataacgtgc gcaaatttaa tgcgcaaaat cacaatattc accaaagata acgacggata
     5161 aatcgctttt cggacttaag gagatatggg tcacatgata ttgtaacgca atgaaataac
     5221 aagcatgaaa attatcacgc gaacatcctt ctgaaggcgg cgacaaggat agaaaatatg
     5281 accttatttg cggagtataa cagcccctat ctgtttgcca tcgcgttcgt tttctttatc
     5341 ggcgtgctgg agatgatttc tctgattttt ggccactttc tttcaggcgc gctcgacgcc
     5401 catctcgatc attatgatgc cctgtcatcc ggccctgcgg gccaggcgct tcattatctg
     5461 aatattggac gcgttcccgc cctagtcgtc ctctgtctat tggccggcta tttcggcctc
     5521 ttcggtatcc tcatccagca tggcgggatc atgctctggc aggcgccgct cagcaatctg
     5581 ctgctggtcc cgttaagcat tgtcctgtcg gtctttgccg tgcattacag cgaaaaaatc
     5641 ctcgcgccct ggctacccag agatgaaagc tccgccctcc gggaagagga atttatcggc
     5701 ggcatggcga ttattaccgg ccacgccgcc gtcgccggaa caccttgcga aggaaaattt
     5761 accgataagt tcggccagat tcactattta ctgctggaac ccgaaaaggg aaaagaattt
     5821 aaaaaaggag acaaggtgct gattgtctgc cgactttccg caacgcgtta tttggctgag
     5881 cgtaccttct atgtttaatt gagaggaact tacataatgg atgatgtttt tggcatattg
     5941 ccatcatgga tgtttaccgc catcgtggcg gttatcgtct tactaattat cgggatcatt
     6001 tttgctcgcc tttatcgccg cgcatctgcg gaacaggcgt ttgtccgtac cgggcttggc
     6061 gggcaaaaag tggtgatgag cggcggcgct attgtgatgc caatctttca cgaaattatt
     6121 ccgatcaata tgaataccct aaaacttgaa gtcagccgtg ctaccgtcga cagcctgatc
     6181 accaaagatc gtatgcgcgt tgacgtggtc gttgctttct tcgtgcgtgt aaaaccctct
     6241 gttgaaggta ttgccacctc cgcacaaacg cttggccagc gaacgctgtc accggaagat
     6301 ctgcgtatgc tggttgagga taaattcgtt gacgccttac gcgctaccgc agcccagatg
     6361 acgatgcatg agctacagga tacgcgtgaa aacttcgttc agggcgtaca aaacaccgtt
     6421 gcggaagatt tgtcgaaaaa cggcctggag ctggaaagcg tctcattaac caactttaac
     6481 caaacgtcca aagagcattt caatccaaac aatgcctttg atgccgaagg tctgacgaaa
     6541 ctgacgcagg aaaccgaacg ccgccgtcgt gaacgtaatg aagtggaaca ggatgtggaa
     6601 gtggcggtgc gcgaaaagaa ccgcgacgcg cttgaacgca agctggaaat cgagcaacaa
     6661 gaagccttta tgactctgga gcaggagcaa caggttaaaa cccgcaccgc cgaacaaaac
     6721 gccaaaattg ccgcttttga ggccgagcgc catcgtgaag cagaacagac gcgcattctt
     6781 gctgagcggc agatccagga gacggagatc gaacgtgagc aagcagtacg gtccaggaaa
     6841 gttgaggccg agcgtgaagt acgtattaaa gagatcgaac agcaacaggt gacagaaatc
     6901 gccaaccaga cgaaatctat cgccattgcc gccaaatccg agcagcaatc gcaagcggaa
     6961 gcgcgcgcca acgacgcgct ggccgatgcg gttcgcgccc agcaaaacgt agaaaccacc
     7021 cgccagaccg ccgaagcgga tcgcgccaag caggtcgctc tgatcgccgc ggcgcaggat
     7081 gcggaaacca aagcggtcga actgaccgtt cgggcaaaag cagagaaaga agcggcagaa
     7141 ttgcaagccg ccgccatcat cgaactggcg gaagcagcgc gtaaaaaagg tctggcggaa
     7201 gccgaagcgc aacgggcgct gaatgacgct atcaacgtac tatctgacga acaaaccagc
     7261 ctcaaattta aactagcgct cttacaatcg ttgcctgctg ttattgagaa gtctgttgaa
     7321 ccgatgaaat ccatcgacgg cattaagatt attcaggtcg atggcctcaa tcgcggcgcg
     7381 acggcgggcg acgtcgccgc tggcggcgct aacgggggaa acctggcgga acaagcgtta
     7441 tctgccgcgc tcacctatcg tacccaggcg ccgctgatcg attcgctgtt aaacgagatt
     7501 ggcatcgccg gcggctcgct aaaggcgctg accacgccgt tggtttcatc ggcaacggat
     7561 gagattaatc gcgaagcaac gataaaagag caataacctc cccgccatat ctcctgtccc
     7621 tggccataag gccggggatt tttttatctt ttttccacct tgtctgtaca aagcgttatg
     7681 accagcaggc cattttgcgt gggcgatcca gtaacgcaaa atcggcggga gaaagccctt
     7741 gcgccagaca ggccactcac caacaatcgc gatgtcagca aggggctgaa acgggaaagc
     7801 ccctcccgag gaaggggctt taataaggaa agggttatga tgcaccaggt catcatactg
     7861 attgttctgt tactgataag tttcccagct tactaacagc caatcagagg ggggagagat
     7921 cccctctcac ccttattcct ttactttagg tcgaaaaaaa agcagcgtca accgcgagat
     7981 acgcgtcgaa acaaaatgtc cgacgcacct tcaaaatcag cgcccgcagc gtctgtaacg
     8041 cctgatgacg cggttttact tctcgctctc ggtctggatc tttttgatga tattggtcgt
     8101 ggaacaacca tcttcgaagt tcagcaccat gacttcgccg ccgttggccc agacctcttc
     8161 gctgcccgcg atctcttccg gcttatagtc gccgcctttt accagcagat ccggcagaat
     8221 accggcaatc agtcgttgcg gcgtatcctc ttcaaaagag acaacccagt cgaccgactc
     8281 cagcgcgccc agcacgatca tacgctgttc gagcggatta accggacggc tttcgccttt
     8341 cagacgttta gtcgaggcgt cactattgac cgcaacaatc aggcggtcgc ccagtttgcg
     8401 cgcgttcgcc agataagaga cgtggcccgc gtgcagaata tcgaaaacgc cgttggtcat
     8461 gaccactttc tcgccacgct tacgcgcgct ggcgacggcc tgtctcaact cctcttcggt
     8521 catgacgccg aagccggtat ccgcgcgtcc gcgcactgcg ttttccagct caatagggga
     8581 aaccgttgac gtcccgagtt tacctaccac tacgcccgcc gccgcattgg cgaaataaca
     8641 cgcctcctcc agggtatttc ccgccgccag cgtcgccgcc agcacgccga tcaccgtatc
     8701 gcccgcaccg gtaacatcat aaacttcctg cgcctgcgtc ggcatatgta gcggcgcttt
     8761 attcggttgc agcagcgtca ttccctgttc ggaacgcgtg accaacagcg cggaaaggtc
     8821 gtaatcggca atgagcttca tgccgcgttc aaccagttcg tcttcgcttt tacatttccc
     8881 cgcaaccgcc tcgaattcag aaaggtttgg cgtcagcagc gtggcgccgc ggtaacgttc
     8941 aaaatccgtt cctttcggat cgatgagcac cggcacgccc gcctggcgcg ctagggaaat
     9001 catagtctgc acgctggtca gagcgccttt ggcataatcg gacaatacca gcgcgccgat
     9061 cgatcccagc gcctggttga tacgctcatg caacggctgc gggtccacgc cctcaaagcc
     9121 ttcttcaaaa tcaagacgaa tgagctgctg attacgtgat agtacgcgca gtttggtaat
     9181 cgtcggatgc gtcggcacag aaacgaagtc gcacttcaca ttgacctccg ccagcgtttt
     9241 gctcagcgcg cgcgcggcgt catcaatacc cgtcaggccg accagacggg cgttcgctcc
     9301 cagagacgca atgttcatcg ccacgttcgc cgcgccgccc ggacgttcct caacggtatt
     9361 taccttaacc acgggcaccg gcgcttccgg tgaaatacgg caagtggggc cataccaata
     9421 gcgatccagc attacatcac ccacaaccat gacgcctgca cgttcaaacg ctggcagatt
     9481 tactttcatt cctgtctcct gagagattca aaatttgcgc gcgataatag cataattcaa
     9541 acggctacca gccacttccg ccagcttgcc tgcaccagcg cgcgctcttt gctaaaacat
     9601 gtctgcgcca catgaccggg aagctcctgc aacgccaggt ggtgcagttc atcacgcagt
     9661 gtggtgtagg ctaccgtcag cgcctgcgct tcgtgttcat ccataatgcc gttttgcgcc
     9721 agaagctcca ggatgcgcac gttatcagac cagcgcgtta atttaggttt ttcatgagcg
     9781 tagcgcagta ccagatattg cgcgataaac tcaatatccg taataccgcc ttcatcagct
     9841 ttaatatcaa aacgatcgcg atgcttattg ccgagatgcg cccgcatttt ctcgcgcatt
     9901 tcacgcactt cagtctgcaa tgtcttaccg tcacgcgccg tcgtcatgat agtgcggcgc
     9961 accgcatcaa actgtgaggt aagctgcggg tcgccatata ccacgcgagc gcgtaccaac
    10021 gcctgatgtt cccaggtcca ggcttcatgc tgctgataat cggcaaacgc gtccgctgaa
    10081 gtcaccagca ttccagccgc gccagagggg cgtagacgcg catccacctc atacaaaatg
    10141 ccggaggagg tgcgcgtact gaacagatgc ataatgcgct gcgccaggcg cagataaaac
    10201 tgccgcccgt cgatttcgcg ttcgccgttg gtcatgacgt ccatcggaca gtcatgcagg
    10261 aagatgagat ccagatcgga actgtagccc agctcccatc cgcccaactt gccataaccg
    10321 acgaccgcaa acccccgccc ctggcgttcg tccagatgcg ctggctgacc ataacgcgca
    10381 accatttgcg tccacgcctg ctgcaccaca gcatcaatca tcgcctccgc cagccatgtg
    10441 aggtgatcgc tcactttcat caccggcagc gtaccggcaa tatccgccgc cgcaatccgc
    10501 aaaagctgtg cctgtttaaa ctggcgtaat gcctccagtt gttgttcttc gtcctcttcc
    10561 ggcacgcgca gcaaatactg gcgtaattcg tcgcggtaag cgtcggtagc cgtcggctga
    10621 taaagcgtgc cggggtcgag cagttcatca agcaacaacg gataacgcgc cagttggctc
    10681 gctatcattg gcgaagcggc gcagagcata atcaggtgtt tcagcgcgcc gggaaattcg
    10741 ctcagcagct ccagataggt ggtgcgagtg acaatccccg ccagcaacgg cgttatccgc
    10801 gatagcgtaa cagcggcgtc ttcgcgggaa cagacgtcag caagcaggtg cggcatcagt
    10861 tggtccagca cctgccgccc gcgcgggccg atagggcgtt tatccagttc cttacggaag
    10921 tcagcgataa gggtcagaac ctgtcgccga tcctcatcgg ctaaatgcgc cagcactggc
    10981 gtcgaatcat cctcctgtag cgcatcctgc catacttcac gccacggctc tgaacgttct
    11041 tcctcctgcg gggtatcggc ttcatcatcg ccaattaatt cgttgaatac gcggcgtaca
    11101 ttagccatat gatccgtcag ttcgccaaca agctgcggcc agttctccgc cttcattccc
    11161 caggccagcc gcgcccgatt cagatcgtcg gcaggcaacg tttgcgtctg ttcgtcattg
    11221 atgctttgca gcagattctc cagacgacgt agaaaaagat aggccacgcg tagttgcgcc
    11281 acgtcattct caggcagcaa atgcagcgca gcgatagcat ccagcgtcgg cagtaacgaa
    11341 cgcgactgta gcgacggctc gcgtccgccg cggatcagct ggaatacctg cacgataaac
    11401 tcaatttccc gaataccgcc cgcgccaagt ttaatgttgt ctttcaaacc gcggcgtcgc
    11461 acttcgcggg cgatcatccc tttcatatta cgtagcgact ggatgacgct gaaatcgata
    11521 tagcggcgga aaacgaaagg ccgcagcatg gcgcgtaatt cacgagacca ggcgtcgtcg
    11581 ttatcgccca ttagccgcgc tttcaccatg gcgtagcgtt cccagtcgcg tccttgctcc
    11641 tgatagtaat cctccagcgc ggcaaaactc agtaccagcg ggccgctgtc gccaaacggt
    11701 cgcaggcgca tgtctacccg atagacaaaa ccatccattg tgggctgatc cagcgctttg
    11761 atcagccgct gcccgagacg cgtaaaaaac tgggcgttat cgagttcacg acgcccgccc
    11821 cgggtctcgc catgttccgg ccaggcgaaa atcagatcga tatcagacga aaaattcagt
    11881 tcgccgccgc ccagcttgcc c
//
LOCUS       DAJVKX010000136        11892 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.136, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000136 DAJVKX010000000
VERSION     DAJVKX010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11892
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.136"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            7..195
                     /locus_tag="OPY25_003717"
     CDS             7..195
                     /locus_tag="OPY25_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929219.1"
                     /translation="MQDYFLESLKLQRIDFFLKLVAASECSDEEKGLALQWVSELTDE
                     LMAKIRSHEYSRSMDVIS"
     gene            complement(263..562)
                     /locus_tag="OPY25_003718"
     CDS             complement(263..562)
                     /locus_tag="OPY25_003718"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929220.1"
                     /translation="MKRITFSFTLVAIIIALAGCALPDKDGDFRAYVHTCQQYAYGKS
                     YAFENRDFAYKVCKDAAKLWSDEVPGYVIRQIQLHPEIPSEEIKYAAMAGSLGNN"
     gene            complement(671..1549)
                     /locus_tag="OPY25_003719"
     CDS             complement(671..1549)
                     /locus_tag="OPY25_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929221.1"
                     /translation="MAMSLSCQLILLGLALFFYDWDRDMKKLTGVIAFALLLTACDKP
                     KIDASSDQSMKESIQKVRESLPADKKAQFDDAVKVVAFSQINMRELMQAGTSSGDVYE
                     TKIKSALEGKTGDEVINYAQTIRLEREKREKEQALQEIKELEAKQTSATQAAEKMKAF
                     KVERSRFYFQKEDYGNDQPILDISVENGTDKAVARVFFKGVIASPGRSVPWFSDVFNY
                     KISGGLEPGEKANWKLAPNRYSDWGKLKVPADAIFTVTVIGLEDADGKSIYGDAEFSE
                     RDADRLNQLRDKYLSK"
     gene            2163..3077
                     /locus_tag="OPY25_003720"
     CDS             2163..3077
                     /locus_tag="OPY25_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929222.1"
                     /translation="MPYQLVELSPVANDLEQLGTKEKFWFYFSDDTVNLQLFKYSRLG
                     TGEHWSEKCAAELCHLLNIPHASYDLARYNGRFGVVTQNIIPSGFRMVMGNEVLHSST
                     FDYPGPLQAGEKPVRVREHTVTRVLGCLDRESIKPPPSVYDLTGLNAADVFCGFLMLD
                     ALVSNQDRHHENWAIMLNNETGEQFLCPTYDHAASLGREMLDDERNERLNTKDKNRQI
                     PCFVRKARSELFKAKTDKKPLLTVEAFQHAVEGRVAARDHWLGKLSVLTEDSITDVFN
                     QVPSSCISDSARRFATLMVMENRRRLLE"
     gene            3074..3814
                     /locus_tag="OPY25_003721"
     CDS             3074..3814
                     /locus_tag="OPY25_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HCS0929223.1"
                     /translation="MTNTNSVYVAWQAPDTRDWHVVGNLQERKSGYVFRYTKGALKST
                     KFTKFSGMSDVRETYVSEELFPLFKNRLLSPRRPEYPSFIKWLGFEEDKVNPIDILAR
                     SGGLRSTDQLQIFKKIDVDSDGNFEHFFFLHGLGYLNSLANARVSELKPGQILRLCLD
                     LQNEYDGDAVVVRADKPAEIVGYCPRYLSNDIKKMLLDDPKSITLTVEKISDDAPHNY
                     RLLCKLSGVLSQACQSTLIPQDEFEPIE"
     gene            complement(3849..4886)
                     /locus_tag="OPY25_003722"
     CDS             complement(3849..4886)
                     /locus_tag="OPY25_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCS0929224.1"
                     /translation="MGKRKKNRAAAMNQIQHKSQTSAEAFSFGDPVPVLDRRELLDYV
                     ECVQMDRWYEPPVSFDGLARTFRAAVHHSSPIAVKCNILTSTYIPHPLLSQQAFSRFV
                     QDYLVFGNAYLEKRTNRFGEIIALEPALAKYTRRGLDLDTYWFVQYGMTTQPYQFTKG
                     SIFHLMEPDINQEIYGLPGYLSAIPSALLNESATLFRRKYYINGSHAGFIMYMTDAAQ
                     NQEDVNNLRNAMKSAKGPGNFRNLFMYSPNGKKDGLQIIPLSEVAAKDEFLNIKNVSR
                     DDMMAAHRVPPQMMGIMPNNVGGFGDVEKASRVFVRNELMPLQKRLQEMNDWLGKEAI
                     QFNTYSLDIVP"
     gene            complement(4886..6652)
                     /locus_tag="OPY25_003723"
     CDS             complement(4886..6652)
                     /locus_tag="OPY25_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HCS0929225.1"
                     /translation="MNTTLTPADLDPRRQAMLLYFQGYRVARIAEMLGEKVATVHSWK
                     KRDKWGDYGPLDQMQLTTAARYCQLIMKEHKEGKDFKEIDLLARQSERHARIGKFNNG
                     GNEADLNPNVANRNKGPRRQPEKNVFTDEQIEKLEEIFHSSMFNYQRHWWEAGKTNRI
                     RNLLKSRQIGATFYFAREALIDALLTGRNQIFLSASKAQAHVFKQYIIDFAKEVEVEL
                     KGDPMVLPNGATLYFLGTNARTAQSYHGNLYLDEYFWIPKFQELRKVASGMAIHKKWR
                     QTYFSTPSSLTHSAYPFWSGALFNRGRNKADKVDIDLSHNNLAPGLLCADGQYRQIVT
                     VEDAVRGGCNLFDLDQLRMEYSPDEYQNLLMCEFVDDLASVFPLSELQACMVDSWEVW
                     TDFHALALRPFGWREVWIGYDPAKGTQNGDSAGCVVVAPPAVPGGKFRILERHQWRGM
                     DFRAQADAIKKLTEQYNVTYIGIDSTGVGHGVYENVKAFFPAVREFVYNPNVKNALVL
                     KAYDIISHRRLEFDAGHTDIAQSFMAIRRATTASGNRPTYEASRSEEASHADLAWATM
                     HALFNEPLQGESANTSNIVEIF"
     gene            6795..7628
                     /locus_tag="OPY25_003724"
     CDS             6795..7628
                     /locus_tag="OPY25_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HCS0929226.1"
                     /translation="MTVKAKRFRIGVEGATTDGREIQREWLEQMAASYNPAVYTALIN
                     LEHIKSYLPDSTFNRYGKVTALFAEEITEGPLAGKMALYADVEPTESLVELVKKGQKL
                     FTSMEVSPKFADTGKAYLVGLAATDDPASLGTEMLTFSASAAHNPLANRKQNPANLFT
                     AAEETVIELEEIQEDKLSLFARVTALFTKKEQSDDARFSDVHKAVELVATEQQNLSAR
                     TEKSLSEQEERLSELETALQAQQTAFNELVNKLSHEDSRQDYRQRATGGNAPADTLTN
                     C"
     gene            7645..8703
                     /locus_tag="OPY25_003725"
     CDS             7645..8703
                     /locus_tag="OPY25_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HCS0929227.1"
                     /translation="MKKNTRFAFNAYLQQLARLNGVAVEELSSKFTVEPSVQQTLEDQ
                     IQQSAAFLTLINVTPVTEQSGQLLGLGVGSTIAGTTDTTAKEREPVDPTLMVDVEYKC
                     EQTNFDTVLTYAKLDLWAKFQDFQVRIRDAIVKRQALDRIMIGFNGVKRAKTSNRSEN
                     PLLQDVNKGWLQKIREDAPDHVMGSTTTGGETTPGAVKVGKGGEYANLDAVVMDAVNE
                     LIDVVYQDDDDLVVICGRELLSDKYFPLVNKEQENSEKLAADMIISQKRMGGLQAVRA
                     PFFPPNALLITRLDNLSIYWQEGTRRRSVIDNPKRDRIENFESVNEAYVVEDYRCAAL
                     VENIQIGDFSAAAAEAGA"
     gene            8707..9357
                     /locus_tag="OPY25_003726"
     CDS             8707..9357
                     /locus_tag="OPY25_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HCS0929228.1"
                     /translation="MSLSPARQHRLRVQAEQAAREGGSVRHASGYDLMLLQLAEDRRR
                     LKGVQSTVKKAEIKVELLPKYAAWAEGVLAAGGAQQDDVLMYVMLWRIDAGDYAGALE
                     IGRHALRHGWVMPLGNRNVQTVLAEEMADAAQSAMLAATGFDADLLLQTLELTDGLDM
                     PDQSRARLHKAIGAVLSESNPASALNHLNHALQLDPRCGVKKDKQQLERRLRNDSR"
     gene            9453..9917
                     /locus_tag="OPY25_003727"
     CDS             9453..9917
                     /locus_tag="OPY25_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HCS0929229.1"
                     /translation="MKFVAPEQAPEQAEIIRNTPFWPDVDLSEFRSMMRTDGTVTQPR
                     LKQVALSAISEVNAELYEFRRRQQMLGYASLAEVPAEQLDGKSERIQHYFNAVYCWAR
                     AMLNERYQDYDATASGVKRGEELAEASGDLWRDARWAISRVQDAPHCTVELI"
     gene            9917..10120
                     /locus_tag="OPY25_003728"
     CDS             9917..10120
                     /locus_tag="OPY25_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HCS0929230.1"
                     /translation="MKVRAHQYDTVDALCWRHYGRTQGVTEQVLKANPGLAEYGPFLP
                     HGLQVELPDIPTTTTVQTVQLWD"
     gene            10124..10339
                     /locus_tag="OPY25_003729"
     CDS             10124..10339
                     /locus_tag="OPY25_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929231.1"
                     /translation="MTLERISAFITYCIAVVLAWLGDLSIKDASTLGGLMIGVLMLAI
                     NWYYKHKAYQLLRDGQISREDYESINR"
     gene            10320..10832
                     /locus_tag="OPY25_003730"
     CDS             10320..10832
                     /locus_tag="OPY25_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HCS0929232.1"
                     /translation="MNPSIVKRCLVGAVLAIAATLPGFQQLHTSVEGLKLIADYEGCR
                     LQPYQCSAGVWTDGIGNTSGVIPGKTITERQAAEGLISNVLRVERALERCVKQQPPQK
                     VYDAAVSFAFNVGTGNACSSTLVKLLNQRRWADACRQLPRWVYVKGVFNQGLDNRRAR
                     EMAWCLQGAN"
     gene            10834..11211
                     /locus_tag="OPY25_003731"
     CDS             10834..11211
                     /locus_tag="OPY25_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929233.1"
                     /translation="MKKKLISGLFLMLWMALLIAAMVYPQGIFPVLAASGVWVACLLT
                     WAVIPVALAALIKNGPLWQELRASLLKTITRKENVFTSWVMRLLIVVSLAWTGWAITL
                     VFYLLTVIAFWITRNQMAQQVAA"
     gene            11208..11636
                     /locus_tag="OPY25_003732"
     CDS             11208..11636
                     /locus_tag="OPY25_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HCS0929234.1"
                     /translation="MNRLLLVVLALLLAALGWQTWRLADASQTISTQADELQSKSQAL
                     AKSNSQLISLSILTETNNREQARLYAEAEQTSAQLRQRQRRIEELKRENEDLRHWADT
                     PLPADIIRLRERPALTGGAAYRQWLSASDAVSAGAGSTAH"
     gene            11732..>11892
                     /locus_tag="OPY25_003733"
     CDS             11732..>11892
                     /locus_tag="OPY25_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0929235.1"
                     /translation="MNKPQSLRSALNKAVAYVRDNPDKLHLFVDNGSLVATGASSMSW
                     EYRYTLNVV"
BASE COUNT         2817 a         2900 c         3253 g         2922 t
ORIGIN      
        1 ggaaagatgc aggactattt tttggagtct ttgaagctcc agcgcattga tttttttctt
       61 aagcttgtag cggctagtga gtgtagcgat gaagagaagg ggctggctct gcagtgggtt
      121 tctgaattga ctgatgagtt gatggcgaaa attcgaagcc atgaatacag taggtcgatg
      181 gatgtaatca gttgagcttg tttcgttagg acttgataag ggaaccgaaa aggggcatta
      241 agcccctttc tcataagttg atttagttgt tccccaaaga gccggccatg gctgcatatt
      301 taatttcttc gctgggtatt tcaggatgta gttgaatttg cctgatgaca tagccaggaa
      361 cttcgtcact ccacagtttc gccgcgtcct tacagacctt atacgcgaag tctctattct
      421 caaaggcata ggattttccg tatgcatatt gctgacaggt atgaacataa gctctgaagt
      481 cgccgtcttt atctggcaaa gcacatccag ccaaggctat gatgattgct actaacgtaa
      541 aggagaaagt tatacgtttc atggtctctt tctaagcgtt tagcattatt taactaaggg
      601 gtatctgccg tgatttggta gtccctgata tatattctca gggactatgc tgaagtagat
      661 ttaatttcga ttatttagaa aggtacttat ctctaagttg attcagtctg tcagcatcgc
      721 gttctgaaaa ctcggcgtca ccatagatcg atttcccatc tgcgtcttca aggccaatga
      781 ctgtgacggt aaatatagca tcagccggaa ctttaagttt tccccaatca gagtatctat
      841 taggggctaa tttccagttg gctttctcac ctggttccag acctccagaa attttatagt
      901 tgaagacgtc agagaaccaa gggacgcttc ttcctgggct ggcaataaca cctttgaaga
      961 atactctggc aaccgctttg tctgttccgt tttcaacgct aatatccaga attggctgat
     1021 cattgccgta atcctctttc tggaaataaa aacgggaacg ttcgaccttg aaggctttca
     1081 ttttttccgc agcctgtgtt gcagaggttt gtttggcttc cagttctttt atttcttgca
     1141 gagcctgttc tttctctctc ttctcacgct caaggcgaat agtttgtgcg taatttataa
     1201 cctcatcacc agttttacct tccaacgctg acttaatttt tgtttcgtag acgtccccag
     1261 aagacgttcc agcctgcatt agctctctca tgttgatttg gctaaaggca acgactttaa
     1321 ctgcatcatc aaactgagct tttttatctg caggtaagga ctctcttact ttttgaatgg
     1381 actctttcat cgactgatcg cttgatgcat cgatcttcgg tttgtcacaa gcagtaagca
     1441 gcagagcaaa agcaattacg ccagttaatt tcttcatatc cctatcccaa tcgtaaaaaa
     1501 acaaggctaa tcctaacagg attagctggc atgacaaact catagccata taggtgtgct
     1561 gtataaatta gcgggatgag aaagcctgcg cagaccctca tgttgaaact tgattttagc
     1621 tcaaaagagc tgacactaaa taactgcgcg gaataatgct ccacttcggt tagcccttgc
     1681 tgggtaaggc gtggggccgt tttcttcgcc tgatcctgct gtatctggcc tacagtatgt
     1741 tgcccttacg cgacatgcca catgtcagta aacggcaggt gtagcagtat tagacgcagc
     1801 tatttagtgt gtattaagct ggctcatatt tatgactggt ttcaaagttt gaccgatttt
     1861 catgtcatgc atgtctatgc tgcatgagtt cgcatgatcg tttgaggatc ggtttggcta
     1921 agacatgcca gaactggcgg gcttttgctc atgtcatgca ggtgcatgaa aaccactaca
     1981 taaagcgggc aggcgtggcg gggatacgag cgcgcgctaa gtcatataag agttatatat
     2041 tgatttgatt gctggacatg catacagtat cgctctatca tctaataaat cttagagtat
     2101 ttgacaatgt ttggataaaa tggaacctaa cttattcata atccgctaaa cagggatgtc
     2161 agatgccata ccaattggta gagcttagcc ccgtagctaa cgatcttgaa cagttaggaa
     2221 ccaaagagaa gttttggttc tatttctccg atgacactgt aaatttgcag ttgtttaagt
     2281 actctaggct aggtactggc gagcattggt ctgaaaagtg tgctgctgag ttatgtcatt
     2341 tgcttaacat tccacatgct agctatgatt tggcgcgata caatggtcga ttcggtgtgg
     2401 tgactcagaa tatcattcca tctggtttcc ggatggtaat gggaaatgaa gtgcttcaca
     2461 gttcgacatt cgattatcct gggcctttac aagccgggga aaagccggta agggtcagag
     2521 aacacactgt cacaagggta ttgggttgtt tagataggga atctatcaag cctcctccga
     2581 gtgtatatga tctaaccggg ctaaatgcag cagatgtatt ttgtggattt ttgatgctcg
     2641 atgcacttgt gagtaatcaa gatcgccatc atgaaaattg ggcgatcatg cttaacaatg
     2701 aaactggtga gcagtttttg tgtccaacat acgatcatgc cgctagttta ggaagggaga
     2761 tgttagatga tgagcgtaac gaacggctta atactaaaga taaaaatcga caaatcccat
     2821 gttttgtaag aaaagctcgc tctgagctat tcaaagcaaa aactgataaa aagcccttgc
     2881 tgaccgttga agcatttcaa catgcagttg aagggagagt tgccgctcgc gaccattggt
     2941 taggtaagtt gagcgtttta acagaagatt ccattacaga tgtgtttaac caagtgcctt
     3001 catcgtgtat atccgacagt gcacgtagat ttgcaacgtt aatggtaatg gaaaatcgca
     3061 gaaggttact agaatgacta atacaaactc cgtttacgtc gcatggcagg caccagatac
     3121 cagagactgg catgttgttg gtaacttgca agagcgcaaa tcggggtatg ttttcaggta
     3181 taccaaaggt gctcttaaat ctactaaatt tacaaagttt agcggcatga gtgatgttcg
     3241 tgaaacttat gtttcggaag aattgtttcc tctttttaaa aatcgccttt tatcaccgag
     3301 acgtccagag tatccgagtt tcattaaatg gcttggattt gaagaagata aggtaaatcc
     3361 tatcgatatt cttgctcgct cgggaggctt acgaagcact gatcagctgc agattttcaa
     3421 aaaaattgat gttgattctg atggtaactt tgagcatttt ttcttcttac atggacttgg
     3481 ttacttaaat agcttagcta atgctcgtgt atctgaattg aaaccggggc aaattttgcg
     3541 tctttgcttg gatcttcaaa atgaatacga tggggatgct gttgtcgttc gtgcagataa
     3601 accagctgaa atcgttggtt actgccctag gtatttaagt aatgatatca agaagatgtt
     3661 attggatgat ccaaaatcaa tcactttaac ggtcgaaaag attagcgatg atgctcctca
     3721 taactatcgg ttattatgta aattatcagg agtactaagc caagcctgtc aatcgacgct
     3781 gattcctcag gatgagtttg aacctattga gtaaatgaag aaaagccacc aaacggtggc
     3841 ttttcttatt atgggactat atctagcgag taggtattaa actgtatcgc ctccttgcca
     3901 agccaatcat tcatctcctg taatcgcttt tgtagtggca ttagctcatt tcggacgaat
     3961 acacggcttg ccttctccac atccccaaac cccccaacat tattcggcat aatccccatc
     4021 atttgcggtg gcacacgatg cgccgccatc atgtcgtccc ggcttacgtt cttgatgttc
     4081 agaaactcat cctttgccgc cacttctgac agcgggatga tctgaagccc gtcctttttg
     4141 ccgttaggcg agtacataaa caggttgcgg aagttgcccg gacctttggc gcttttcatc
     4201 gcgttgcgga ggttgttcac atcctcctgg ttctgagcgg catcggtcat gtacattatg
     4261 aatcctgcat ggctgccatt aatataatat ttgcgtcgga acagcgtggc ggactcgttg
     4321 agcagggctg acggaatggc agaaagatag ccgggcaggc cgtagatctc ctggttgata
     4381 tcgggttcca tcagatgaaa gatgctgcct ttcgtgaact gatacggctg ggttgtcata
     4441 ccgtattgca caaaccagta ggtatccagg tctaacccgc gtcgggtgta ttttgccaga
     4501 gcaggctcaa gggcgataat ttcaccgaac cggttcgtgc gtttctccag gtaggcgtta
     4561 ccaaatacca gatagtcctg cacaaaacgt gaaaaagcct gctggctgag cagcgggtga
     4621 gggatgtagg tgctggtcag aatgttgcat ttcaccgcaa tcggtgagct atgatgcacg
     4681 gcggcgcgga aggttcgcgc cagtccgtcg aaactcactg gtggctcata ccagcggtcc
     4741 atctgtacgc attccacata gtccagtaat tcgcggcggt ccagaacagg aacgggatcg
     4801 ccgaagctga atgcttcggc tgaagtctgg cttttatgct ggatctgatt catcgccgct
     4861 gcgcggtttt tcttacgctt tcccatcaaa aaatctccac aatattactg gtattggcgg
     4921 actcgccttg cagtggttcg ttaaacagtg cgtgcattgt tgcccaggcc agatcggcgt
     4981 ggctggcttc ttcgctgcgg ctggcttcat aggtcgggcg gttgccactg gcggtggtgg
     5041 cgcgacggat tgccataaat gactgcgcta tgtcggtgtg tccggcgtca aactccagac
     5101 ggcggtggct gataatgtcg taggccttga gtaccagagc gtttttaacg ttggggttgt
     5161 agacaaactc ccggacggca ggaaagaacg ctttcacgtt ctcataaacc ccgtgaccga
     5221 cgcctgtcga gtcaatgccg atataggtca cgttgtactg ctcggtcagt tttttgattg
     5281 catcagcctg ggcgcggaag tccatcccgc gccactggtg acgctcaaga atgcgaaact
     5341 taccgcctgg cacggctggc ggtgccacca ccacgcatcc ggcgctgtcg ccgttctgcg
     5401 taccttttgc cgggtcataa ccgatccaca cctcgcgcca gccaaacggg cgcagggcca
     5461 gtgcatgaaa gtcggtccag acttcccaac tgtccaccat gcacgcctgc agttcgctga
     5521 gcgggaacac ggacgcgaga tcgtccacga actcgcacat cagcaggttc tggtattcgt
     5581 ccgggctgta ctccatgcgt agctggtcga ggtcgaacag gttacagccg ccgcgcaccg
     5641 catcttccac ggtgactatc tggcggtatt gcccgtctgc gcacagcaag ccgggggcca
     5701 gattgttgtg ggacaggtcg atgtccacct tatcggcttt gttgcgccca cggttaaaca
     5761 gcgcaccgga ccagaacgga taagcactgt gtgtaaggct ggatggcgtg gaaaaatagg
     5821 tttgtcgcca ttttttgtga atagccatac cggaagccac tttgcgcagc tcctggaatt
     5881 tcggtatcca gaaatattca tccagataca ggttgccgtg gtaactctgg gccgtgcggg
     5941 cattggtgcc gaggaagtaa agcgtggccc cgttgggaag caccatcgga tcgcctttca
     6001 gctccacctc cacttctttg gcgaagtcga tgatgtactg tttaaagacg tgggcctgtg
     6061 ccttactggc ggaaaggaaa atctggttac gtccggtaag cagggcgtca atcagggctt
     6121 cacgggcaaa gtaaaaggtc gcgccgatct ggcgtgactt cagcaggttg cggatgcggt
     6181 tggtttttcc ggcttcccac cagtggcgct ggtagttgaa catggaggaa tggaaaattt
     6241 cttccagctt ctcaatctgt tcatcggtga aaacgttctt ttccggctga cggcgtgggc
     6301 ctttgttgcg gttggcgacg ttagggttta agtcggcttc gttgccgcca ttgttaaact
     6361 tgccgatccg cgcgtggcgt tccgactggc gcgccagcag gtcaatctct ttgaaatctt
     6421 tcccttcttt gtgctccttc ataatgagct ggcagtagcg tgcggcggtg gtgagctgca
     6481 tctgatccag cggcccatag tcaccccact tgtcgcgttt tttccagctg tgaacggttg
     6541 caactttctc gcccagcatt tcagcaatgc gggctacgcg gtatccctga aagtacagca
     6601 gcatggcctg ccgacgggga tcgagatctg cgggtgtcag tgtggtgttc atggcacaaa
     6661 cctacagcct tgaatgaagg ctttccccgc ctgcggtttg tgtggttgtc ggtacaaata
     6721 ccgcgcattg tttcactgcc cccatcaccg caaccataag gctccagtaa gttttttcta
     6781 acggagcacg gctcatgaca gtgaaagcaa agcgttttcg catcggggtg gaaggtgcca
     6841 ctaccgacgg acgcgaaatc cagcgtgaat ggctggaaca gatggcagcc agctacaatc
     6901 cggcggtgta taccgcgctg attaaccttg agcacatcaa gtcttatctg ccggacagca
     6961 cctttaaccg ctacggcaag gtgacggcgc tgtttgctga agaaatcacg gaaggtccgc
     7021 tggcgggcaa gatggcactg tatgccgacg ttgagccaac ggagtccctg gtggagctgg
     7081 tgaaaaaagg ccagaaatta ttcacctcta tggaagtcag cccgaagttc gctgatacgg
     7141 gcaaagccta cctggtcggc ctggctgcca ctgatgaccc tgccagtctg ggcactgaaa
     7201 tgctgacatt cagcgccagt gcagcccata acccgctggc aaaccgcaag cagaatcccg
     7261 ccaatctctt taccgccgca gaggaaacgg tgatcgaact ggaagaaatc caggaggaca
     7321 agctgtccct gtttgcccgc gtcacggcac tgttcaccaa aaaagagcag tccgacgatg
     7381 cccggttctc tgatgtgcat aaggccgtgg agttggtcgc cactgagcag caaaacctga
     7441 gcgcacgcac cgaaaaatcc ctgtctgagc aggaagaacg tctgtctgag ctggagactg
     7501 ccctgcaggc acagcagaca gcctttaacg aactggtgaa taagctgagt catgaagaca
     7561 gccgccagga ctaccgccag cgtgcaacag gcggtaacgc ccccgctgac actctgacca
     7621 attgctgatg gagcacaaaa cccgatgaag aagaataccc gctttgcttt taacgcttac
     7681 ctgcagcagc tggcgcgtct gaacggtgtt gcagttgaag aactgtccag caagttcacc
     7741 gtcgaaccgt ccgtgcagca gacgctggaa gaccagatcc agcagtccgc cgctttcctg
     7801 acactgatta acgtcacgcc agtgactgag cagtccggtc agttgctggg gctgggtgtt
     7861 ggcagcacca ttgccggaac cactgatacc accgcgaaag agcgtgaacc tgtcgatccg
     7921 acgctgatgg tcgatgtgga atataaatgc gagcagacta actttgacac ggtgctgacc
     7981 tacgcgaagc tggacctgtg ggcgaagttt caggatttcc aggtgcgtat ccgtgacgcc
     8041 atcgtgaaac gtcaggcact ggaccgcatc atgatcggct ttaacggcgt gaagcgtgcg
     8101 aaaacctcca accgtagcga aaacccgctg ctgcaggatg tgaataaagg ctggctgcag
     8161 aaaatccgtg aggatgcacc ggatcacgtc atgggcagca ccaccacggg cggtgaaact
     8221 acaccgggtg cggtgaaagt cgggaaaggt ggcgaatatg ccaacctaga cgccgtagtg
     8281 atggatgccg tcaatgagct tatcgacgtg gtttaccagg acgatgacga tctggtggtt
     8341 atttgcgggc gtgaactgct gtctgacaag tatttcccgc tggtcaacaa agagcaggaa
     8401 aacagtgaaa aactggctgc cgatatgatc atcagtcaga aacgcatggg tggcctgcag
     8461 gccgtgcgtg cgccgttctt cccgccgaat gcgctgctaa tcacccgtct ggataacctg
     8521 tccatctact ggcaggaagg cacccgccgc cgttcagtta tcgacaaccc gaaacgtgac
     8581 cggattgaaa actttgaatc cgttaacgaa gcctatgtgg ttgaggacta ccgctgcgcc
     8641 gcactggtgg aaaacatcca gattggcgat ttcagcgccg ctgcagcaga agccggagcg
     8701 taacctatga gcctgagtcc cgcacggcag catcgcctgc gcgttcaggc tgaacaggcc
     8761 gcccgcgagg gcggcagcgt tcgccacgca tctggctatg acctgatgct gctgcaactg
     8821 gcggaagacc gccgccgtct caagggcgtt cagtccacgg tcaaaaaagc ggaaataaag
     8881 gtggagctgc tgccgaaata tgccgcctgg gcggagggcg tcctggctgc cggaggcgct
     8941 caacaggatg acgtgctgat gtacgtgatg ctgtggcgca ttgatgccgg agattatgcc
     9001 ggggcgctgg agatcgggcg tcatgccctg cgtcatggct gggtgatgcc gctgggtaac
     9061 cgcaatgtgc agaccgtgct ggcagaggaa atggcagatg cagcgcagag cgcaatgctt
     9121 gccgccaccg gctttgatgc cgatctgttg ctgcagacgc tggagctgac agacggtctg
     9181 gatatgccgg accagtcacg ggcgcgtctg cataaagcga ttggcgctgt tctgagtgaa
     9241 agcaatccgg cttccgccct taatcatctc aaccatgcgt tacagctcga tccccgctgt
     9301 ggcgtgaaaa aagacaaaca gcagctggag cgcagactgc gcaatgacag ccgctgacag
     9361 aacgtgcccc cgcgcacggg cggcacgggg tggcgaaagg cactgccaca tcaaaacccc
     9421 gtccaccgcc ctttatttca ggagaaagca gcatgaagtt tgttgcgcca gaacaggcac
     9481 cggaacaggc ggaaatcatc agaaatacgc cgttctggcc tgatgtggac ctgtcggagt
     9541 ttcgcagcat gatgcgcact gatggcacgg tgacgcagcc gcgtttaaag caggttgcgc
     9601 tgtcggcaat ttcggaggtc aacgcagagc tgtatgagtt tcgcagacgc cagcagatgc
     9661 tggggtatgc ctcgctggca gaagtcccgg cggaacaact ggacggcaaa agcgagcgca
     9721 ttcagcacta tttcaacgcg gtttactgct gggcacgcgc catgctcaac gaacgttacc
     9781 aggactatga cgccacggca tccggtgtga agcggggcga agaactggca gaagccagcg
     9841 gtgatttgtg gcgtgacgcc cgctgggcca tcagccgggt gcaggatgca ccgcactgta
     9901 cggtggagct tatctgatga aagtgcgtgc gcatcagtat gacacggtgg acgcgctttg
     9961 ctggcgtcat tacgggcgca cgcagggtgt cacggagcag gtactgaagg caaatccggg
    10021 gcttgccgaa tacggcccct ttttacctca cgggctgcag gtggagctgc cggacattcc
    10081 gaccaccacc accgtgcaga ccgtccagct atgggactga attatgacgc ttgagcgaat
    10141 cagcgccttt atcacgtatt gcatcgccgt cgtgctggcc tggctgggcg atttgtccat
    10201 caaggatgcc tcaacgctgg gcggcctgat gattggtgtg ctgatgctgg ctatcaactg
    10261 gtactacaaa cacaaagcct accagcttct gcgcgacggg cagatctcgc gggaggacta
    10321 tgaatccatc aatcgttaaa cgctgccttg tcggggccgt gctggctatt gctgccacgc
    10381 tgccgggttt tcagcagctt cacacctccg tggaggggct gaaactgatt gccgattacg
    10441 aaggttgtcg tctgcagccg tatcagtgca gcgcgggtgt ctggaccgac ggcattggta
    10501 atacgtcagg cgtcattccc ggcaaaacca ttacggagcg acaggcagca gaagggctga
    10561 tctccaacgt gctgcgtgtg gagcgggcgc tggaaaggtg tgtgaagcaa cagccgccgc
    10621 agaaggtgta tgacgctgcg gtgtcgtttg ccttcaacgt gggaacgggc aatgcctgca
    10681 gttccacact ggtgaaatta ctcaatcagc ggcgctgggc ggatgcgtgc cgacagttgc
    10741 cgcgctgggt ttatgtgaaa ggtgttttta atcaggggct ggataaccgc cgtgcgcggg
    10801 agatggcctg gtgcttacag ggagcaaact gaaatgaaaa agaaattaat cagcggactg
    10861 tttctgatgt tatggatggc gctgttaatc gcagcaatgg tgtatccgca ggggattttt
    10921 ccggtactgg cagcgtccgg cgtttgggta gcctgtttgc tgacatgggc ggtaattccg
    10981 gtagcactgg ctgcgttaat taagaatggc ccgctctggc aggagttaag ggcatctttg
    11041 ctgaagacaa ttacccgaaa agaaaacgta tttaccagtt gggtgatgcg attgctgatt
    11101 gttgtaagtc tcgcctggac ggggtgggct attaccctgg tcttttatct actgaccgtt
    11161 attgccttct ggatcacccg taatcagatg gcgcaacagg tagcagcatg aaccggttgc
    11221 tgctggttgt gctggcgtta ttactggcgg cgctgggctg gcagacgtgg cggctggctg
    11281 atgccagcca gaccatcagc acgcaggcag acgagctgca gagcaaaagc caggcactgg
    11341 caaagagcaa cagccagctt atcagcctgt ccattctgac tgaaaccaat aaccgggagc
    11401 aggcgcggct ctatgccgaa gcagaacaga ccagcgcaca gctgagacaa cgacaacgcc
    11461 ggatcgagga actgaaacgt gagaacgagg atttacgcca ctgggctgat actcctttgc
    11521 ctgctgacat tatccggctg cgggaacgtc cggcactcac cggaggtgca gcttaccgtc
    11581 agtggttgtc cgcgagtgac gccgtgtcgg ctggagcagg cagcaccgcg cactaacggt
    11641 gatctgaatg cgttgctgga tgaaaccgag gccgcctggg cggtctgtgc tgacaaagtg
    11701 gacacaatta ttgcgtgtca ggagcgagac agtgaacaaa ccgcagtcct tacgcagcgc
    11761 cctgaataaa gcggttgcct atgtccggga caacccggac aagctgcacc ttttcgttga
    11821 taacggatca ctggtggcaa caggagccag ttccatgtca tgggaatacc gctacaccct
    11881 gaacgtggtg at
//
LOCUS       DAJVKX010000137        11702 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.137, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000137 DAJVKX010000000
VERSION     DAJVKX010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11702
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.137"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(60..287)
                     /locus_tag="OPY25_003734"
     CDS             complement(60..287)
                     /locus_tag="OPY25_003734"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929236.1"
                     /translation="MVIPEVLIGGINVIVDHTNYTNLRRDAQVFFVSPEPVTVTDNLH
                     NSLHFRLFLCVFGLAMQTREAHNQDPRGIDW"
     gene            495..1523
                     /gene="galR"
                     /locus_tag="OPY25_003735"
     CDS             495..1523
                     /gene="galR"
                     /locus_tag="OPY25_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HCS0929237.1"
                     /translation="MATIKDVARLAGVSVATVSRVINDSPKASEASRLAVTSAMESLS
                     YHPNANARALAQQATETLGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQIPGMVLINRILPGLEHRCVALDD
                     RYGAWLATRHLIQQGHTRIGYICSNHTISDAEDRLRGYYDALAESHIPANDRLVTFGE
                     PDESGGEQAMTELLGRGRHFTAVACYNDSMAAGAMGVLNDNGVGVPGEVSLIGFDDVL
                     VSRYVRPRLTTIRYPIVTMATQAAELALALAGKCPTPEVTHVFSPTLVRRHSVSTPTD
                     TGHLSTTD"
     gene            1534..2556
                     /locus_tag="OPY25_003736"
     CDS             1534..2556
                     /locus_tag="OPY25_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCS0929238.1"
                     /translation="MMATMLDVSRHAGVSKATVSRVLNGTGQVKESTRQKVFTAMQAL
                     DYRPNLLARSLANRTSNSIGLVVSTFDGFYFGSLLRRASRQAEFHNKQLIVTDGHDTP
                     EREQKAVQMLADRQCDAIILYTRYMDEPTILSLIDATEMPLVIINRNITQAHDRAIFF
                     EQETAAFQAVEYLITQGHRDIACITLPVHTPTGTSRVAGYRKALEKYGIPWQPAKVKY
                     GDYTLTRGYDACRELLEEGVTFSALFACNDDTALGAAKALRQAGLRIPQDVSLFGFDD
                     APGATWLEPGLSTVYLPIEDMIATAIDQAVRLANSEPVAPIPPFTGTLILRESVAAGP
                     FFQRPV"
     gene            complement(2566..3828)
                     /gene="lysA"
                     /locus_tag="OPY25_003737"
     CDS             complement(2566..3828)
                     /gene="lysA"
                     /locus_tag="OPY25_003737"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCS0929239.1"
                     /translation="MSLPHYHAETDLNAENLLRLPAEFGCPVWVYDAHIIRRQIAALQ
                     QFDVVRFAQKACSNIHILRLMRAQGVKVDSVSLGEIERALAAGYDPQTCPDDIVFTAD
                     VIDAATLARVSELHIPVNAGSVDMLTQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWHSDLPAALAVMQKYRLKLVGIHMHIGSGVDYGHLEQVCGAMVRQVLECGQD
                     VEAISAGGGLSIPYHEGEEPVDTRHYYGLWNAAREQIARHLGHAVKLEIEPGRYLVAQ
                     SGVLVTQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHRISALAADGRALENGPWVE
                     TVVAGPLCESGDVFTQQEGGMVETRALPAVIPGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALEML"
     gene            3946..4881
                     /locus_tag="OPY25_003738"
     CDS             3946..4881
                     /locus_tag="OPY25_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0929240.1"
                     /translation="MAAVNLRHIEIFHAVMTAGNLTEAARLLHTSQPTVSRELARFEK
                     VLGLTLFERTRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPPLLPPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHAPAGTTR
                     TELLTLNEVCVLPCDHPLAAKTVLTPDDFQGENFISLSRLDSYRQLLDTLFAEHQVKR
                     RMVVETHSAASVCAMVRAGAGVSIVNPLTALDYAASGVTVRRFSIDVPFTVSLIRPLH
                     RPASALVDAFSKHLQTHLSRLVEPLEVILGPMTKA"
     gene            complement(4853..5560)
                     /locus_tag="OPY25_003739"
     CDS             complement(4853..5560)
                     /locus_tag="OPY25_003739"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase"
                     /protein_id="HCS0929241.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQQLGGLHSASLLLHSVD
                     FHDIEVCQRRGEWDKAGDILAQAAQGLQQAGAEGIVLCTNTMHKIAHIIESRCSLPFL
                     HIADATGRAIARQGLHRVALLGTRYTMEQDFYRGRLEQQFAIETIVPEADDRARINQV
                     IFDELCQGIFTDASRHYYLQVIEQLAAQGAQGVIFGCTEIGLLVPQTQSALPVFDTTA
                     IHAADAVSFMLSSSAPE"
     gene            complement(5673..7088)
                     /gene="araE"
                     /locus_tag="OPY25_003740"
     CDS             complement(5673..7088)
                     /gene="araE"
                     /locus_tag="OPY25_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HCS0929242.1"
                     /translation="MVSINDSALTPRSLRDTRRMNMFVSVSAAVAGLLFGLDIGVIAG
                     ALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLGS
                     LGSAFASSVEVLIGARVILGVAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLGI
                     VLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAQKGRHIEAEEVLR
                     MLRDTSEKARDELNEIRESLKLKQGGWALFKANRNVRRAVFLGMLLQAMQQFTGMNII
                     MYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVMA
                     LGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKCR
                     DFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFIGITFWLIPETKN
                     VTLEHIERKLMAGEKLRNIGV"
     gene            complement(7442..8203)
                     /gene="kduD"
                     /locus_tag="OPY25_003741"
     CDS             complement(7442..8203)
                     /gene="kduD"
                     /locus_tag="OPY25_003741"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HCS0929243.1"
                     /translation="MILNAFSLEGKVAVVTGCDTGLGQGMALGLAEAGCDIVGINIVE
                     PTETIARVTALGRRFLSLTADLRQIDGIPALLERAVAEYGHIDILVNNAGLIRREDAI
                     DFTEKDWDDVMNLNIKSVFFMSQAAAKYFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGITRLMANEWAKHNINVNAIAPGYMSTNNTQQLRADAQRSAEILDRIPAGRW
                     GLPGDLMGPVVFLASSAADYINGYTIAVDGGWLAR"
     gene            complement(8258..9094)
                     /gene="kduI"
                     /locus_tag="OPY25_003742"
     CDS             complement(8258..9094)
                     /gene="kduI"
                     /locus_tag="OPY25_003742"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HCS0929244.1"
                     /translation="MDVRQSIHSEHAKTLDTQALRREFLIENIFVADEYTMVYSHIDR
                     IIVGGIMPVSHSVEIGGEVGKQLGVSRLLDRRELGVINIGGAGAIIVDGQRHDIGHRD
                     ALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKKVSPADVAPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYLYFNMEEDSCVFH
                     MMGQPQETRHIVMRNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVQD
                     LR"
     gene            complement(9524..10702)
                     /locus_tag="OPY25_003743"
     CDS             complement(9524..10702)
                     /locus_tag="OPY25_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HCS0929245.1"
                     /translation="MKEVVIVGALRTPIGCFQGTLARHSAVELGSMVVKALIERTGVD
                     ANAIDEVILGQVLTAGAGQNPARQSAIKGGLPTTVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLNDSRTGALPDADNLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRELQDAYALSSQQKARAAIDTGRFKDEIVPIVTQRNGQTAIVDTDEQ
                     PRADASAEGLALLHPAFDSLGSVTAGNASSINDGAAAVMMMSETKAQALGLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERAGWQLTEVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRDARKGLATLCIGGGQGVALTIERD
                     "
     gene            complement(10825..11688)
                     /locus_tag="OPY25_003744"
     CDS             complement(10825..11688)
                     /locus_tag="OPY25_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0929246.1"
                     /translation="MRYSPEALMAFVEAVSCGSFSAAARRLRKSQSTISTAIAHLEAD
                     LGFSLFDRSSRQPVLTEEGKRVLSYVQAILSASDRLDEVALTLSGETETRLTFVLSDT
                     LHPDSLEELMAQFDRQFPHTEFECLIGENDDVIDLLQKGRAQIGLIEARDNYPTDIGA
                     TRLLVQSWMGVYVATTHPLASQTNLQWEQLHTWRELRLNTYLDSNANITRGPAWSAPN
                     YLLLLSMAVQGFGWCVLPCALVEEFAAEKPLAQLDVPGWPRAIAIDLLWNKKTPPGTA
                     GNWLRYHLQQK"
BASE COUNT         2805 a         3308 c         2952 g         2637 t
ORIGIN      
        1 acctgcgcat ccgcgcaggt tggtgcaaga gacaggtacg aagagcgtac cgaataatct
       61 caccaatcaa tacctctggg atcttgattg tgggcttcgc gcgtctgcat cgccagtccg
      121 aaaacgcaaa ggaataaacg gaaatgcaac gagttgtgta aattatccgt tactgttaca
      181 ggttcaggcg aaacaaaaaa aacctgcgca tctctacgca ggttggtgta attcgtgtga
      241 tcaacaatga cgttgattcc acctatcaat acctctggga tcaccactct atcaacctga
      301 ctcgctggcc tgccagcaga caatcgcaac agcgcttcgc aaactgtaac gaaagatttg
      361 tattgtcact ttacagacgc atttctcccg tgcaggtcac atttgtccga cacggcgggg
      421 caagaggctt gaacagacgt tcattttccg taaaactggc gtaatgtaag cgtttaccca
      481 ctataggtat tatcatggcg accataaaag atgtagcccg actggccggt gtttcagtcg
      541 ccaccgtttc tcgcgttatt aacgattcgc caaaagccag cgaagcgtcc cggctggcgg
      601 tgaccagcgc aatggagtcc ctgagctatc accctaacgc caacgcgcgc gcgctggcac
      661 agcaggcaac ggaaaccctc ggtctggtgg tcggcgacgt ttccgatcct tttttcggcg
      721 cgatggtgaa agccgttgaa caggtggcgt atcacaccgg caatttttta ctgattggca
      781 acgggtatca taacgaacaa aaagagcgtc aggctattga acagttgatt cgtcatcgtt
      841 gcgcagcgtt agtggtacac gccaaaatga ttccggatgc ggacctggcc tcattaatga
      901 agcaaatccc cggcatggtg ctgattaacc gcattttacc ggggttagaa catcgctgtg
      961 tcgcgctgga tgaccgttac ggggcatggc tggcgacccg gcatctgatc cagcaaggtc
     1021 atacgcgtat tgggtatatc tgttccaatc acactatctc tgatgccgaa gatcgcctga
     1081 ggggctatta cgatgcgctg gcggaaagcc atatcccggc taacgatcgg ctggtgacgt
     1141 tcggcgaacc ggatgaaagc ggcggcgagc aggcgatgac tgagttatta ggtcgcggca
     1201 gacattttac cgcggtggcc tgctataacg actcgatggc ggccggcgcg atgggagtat
     1261 taaatgataa tggcgtgggg gtgccgggcg aagtatcgct catcggtttt gatgatgtac
     1321 tggtctcacg ctatgtgcgt ccccgactga ccaccattcg gtatccgatc gtcaccatgg
     1381 cgacacaggc ggcggagctg gccttagcgc tggcagggaa atgccctacg ccagaagtaa
     1441 ctcatgtatt tagtccgaca ctggtacgcc gacattcggt gtccacgccg acggataccg
     1501 ggcacctgtc gacaaccgat taatcagggt agcatgatgg cgacaatgct ggatgtttcc
     1561 cgccatgcgg gcgtatcaaa ggccaccgtc tcacgagtgc tgaatgggac ggggcaggta
     1621 aaagaaagca cgcgccagaa agtgtttacg gcgatgcagg ctctggacta tcgccccaac
     1681 ctgctggcac gctcgctggc aaatcgcacc agcaacagca tcggtctggt cgtctctacg
     1741 tttgacggct tctattttgg cagtttgttg cgccgggcgt cgcgccaggc ggagtttcat
     1801 aacaagcagt tgatcgtcac cgatggtcac gatacgccgg aacgagagca gaaagccgta
     1861 caaatgttgg ccgacagaca gtgcgacgct attattcttt acactcgcta tatggatgag
     1921 ccgacgattt tgtcgttgat tgacgccacg gaaatgccgc tggtgattat taatcgcaac
     1981 atcactcagg cccacgatcg cgctattttc ttcgagcagg agacggcggc attccaggcg
     2041 gtggaatacc tgattacgca gggccatcgc gatatcgcct gtattacgct gcctgttcat
     2101 actcccaccg gcacatcacg cgtagcgggt tatcgaaagg cgctggaaaa atatggcatt
     2161 ccctggcaac cggcaaaagt gaaatacggc gattacacgc tgacgcgcgg ctatgacgcc
     2221 tgccgggaat tactggagga aggcgtcacg tttagcgcgc tattcgcctg taatgatgac
     2281 acggcgctgg gcgcggcaaa agcgctgcgc caggccggat tacgcatccc gcaggatgtg
     2341 tcgctgtttg gttttgacga tgcgccgggc gcaacctggc ttgagccggg gctttcaaca
     2401 gtctatttac ccatcgagga tatgatagcc accgcaattg atcaggccgt tcgtctggcg
     2461 aacagcgagc cggtcgcccc gatcccgccc tttaccggca cgctgattct gcgcgagtcc
     2521 gtcgccgcgg gcccgttttt tcaacgtccg gtctaatgat gcgcttcaga gcatctccag
     2581 cgctaacagc tcttcaatgg tttgacgacg gcggatcagc cgcgcctgtc cattgtcaaa
     2641 cagtacttcc ggcaggagcg ggcggctgtt gtaattcgat gacatagacg cgccgtacgc
     2701 gccggtatcg tgcaatacga ggtaatcgcc ggggatgacc gcaggtaagg cgcgtgtttc
     2761 aaccattccc ccttcctgct gcgtaaaaac atcgcctgat tcgcatagcg gcccggcgac
     2821 caccgtctcg acccacgggc cattttcaag cgcgcgacca tccgccgcca gcgccgaaat
     2881 acggtgatag ctaccgtaca tcgccgggcg catcagatcg ttaaaaccag cgtcgaccag
     2941 cacgaaatgg cggcttccca tctgttttac gctacgcacc tgcgttacca gcacgcccga
     3001 ttgcgccacc agataacgtc cgggttcgat ctcaagtttg accgcatgtc ccagatggcg
     3061 ggcgatttgc tcgcgcgccg cgttccacag accatagtaa tggcgcgtat caacgggctc
     3121 ttctccctca tgataaggta tcgagagtcc gccgcctgcc gaaatcgcct ccacatcctg
     3181 accacattcc agcacctggc gtaccatcgc gccgcaaacc tgctccagat ggccataatc
     3241 gacgccggaa ccaatgtgca tatggatacc gacaagtttc agtcggtatt tctgcattac
     3301 cgccagcgcc gccggaagat cgctatgcca gatgccgtgt ttgctgtttt cgcccccggt
     3361 gttggttttc tggctgtggc cgtgaccaaa gccaggattc acgcgcaacc agacgcgatg
     3421 cccaggcgaa acctgaccaa gctgcgtcag catatctacc gagccggcat tgaccggaat
     3481 atgcagttca ctgacgcgcg ccagcgtggc ggcgtcaatc acatcggcgg taaaaacgat
     3541 atcatcaggg cacgtttgcg gatcgtagcc cgccgccagc gcacgttcga tctcccccaa
     3601 tgaaacagaa tccaccttga caccctgcgc gcgcattaag cgcaggatat gaatgttcga
     3661 acaggctttt tgcgcaaaac gcacgacgtc aaactgctgc agggcggcta tctgacggcg
     3721 aataatgtgc gcgtcataga cccagaccgg acagccgaat tcagcaggca atctgagcaa
     3781 attttcagcg ttaaggtcag tttcagcgtg ataatgcggc aatgacataa caaactccgg
     3841 aacaggcttt ttaacgatta cgccatacct tagaaagaat aaaaaatatc gttttattgt
     3901 cagtctatgc aaaaatgata tgggataaat gattcaggga aacgtatggc tgccgttaat
     3961 ttacgtcaca ttgaaatttt tcatgccgta atgaccgccg gaaatctcac cgaagcggcg
     4021 cggctgctgc atacctcgca gcctaccgtc agtcgcgagc tggcgcgttt tgagaaagtg
     4081 ctgggattaa cgctgtttga gcgcacacgc gggcgcttac atccgacggt gcaagggcta
     4141 cgcctgttcg aagaggtaca acgctcctgg tatgggttgg atcgcatcgt cagcgcggcg
     4201 gaaagtctgc gcgagttccg tcagggcgaa ctctctatcg cctgcctgcc ggtcttttca
     4261 caatcctttt tgccgccgct actaccgcct tttttggcgc gttatccgga tgtcagcctg
     4321 aatattgtgc cgcaggagtc gccgttgctg gaagagtggc tctccgctca gcgccacgac
     4381 ttagggctga cggagacgct tcatgccccg gcaggaacaa cccgcaccga gttactaacg
     4441 ctgaatgaag tgtgcgtact gccctgcgac catccgcttg ccgccaaaac ggtactgacg
     4501 ccagacgatt ttcaggggga aaactttatc agcctctccc gcctggacag ctatcgacag
     4561 ttgttggata cgttatttgc cgaacatcag gtgaagcgca gaatggtggt ggaaacgcat
     4621 agcgcggcct ccgtctgcgc gatggtgcgc gccggggcgg gcgtttcgat cgttaacccg
     4681 ctgaccgcgc tggactatgc cgccagcggc gtcaccgtcc gccgcttcag cattgacgtg
     4741 ccctttaccg tcagcctgat tcgcccgcta caccgccccg cctccgcgct ggttgacgcc
     4801 ttcagtaagc atttacaaac gcatctttcg cgcctggtcg aaccgctgga ggttattctg
     4861 gggccgatga cgaaagcata aagctcacgg catctgcggc atgaattgcc gtggtatcga
     4921 aaaccggtag cgcgctttgc gtctggggaa caagcaaacc tatttcagta cagccaaaaa
     4981 taacgccctg cgcgccttgc gcagccagtt gttcgataac ctgtaaataa tagtggcgcg
     5041 acgcgtcagt gaatatcccc tgacagagct cgtcaaaaat cacctgattg atacgcgccc
     5101 gatcgtccgc ctccggcacg atggtctcaa tcgcaaattg ctgttccagc cgcccgcgat
     5161 aaaaatcctg ctccatcgta tagcgagtcc ctaatagcgc cacgcgatgc aacccctgac
     5221 gggcgatggc tcgcccggta gcatccgcga tgtgtaggaa aggcagagaa caacgagatt
     5281 caataatgtg cgcgatttta tgcatggtgt tggtacacag cacaatacct tctgcgcccg
     5341 cctgctgtaa cccctgcgcg gcctgcgcca ggatatcgcc cgctttatcc cattcgccgc
     5401 ggcgttgaca tacttcaata tcgtggaaat ctacgctatg cagcagtaag ctcgccgagt
     5461 gcaggcctcc cagctgctgt ttaatgcctt cattgattaa acggtaataa gggatagtcg
     5521 attcccagct catccccccc aacagcccga tcgttttcac tgcgctctcc tttttgtaaa
     5581 gcattatggc agtgaaacaa acttacacat ccgtttccag tctatttttc atcatgccgg
     5641 ataacaggcg tcatccggca tgggaggggg gattacacgc caatatttct tagcttctcg
     5701 cccgccatta gcttgcgttc gatgtgctcc agggtgacat ttttggtttc cggaatcagc
     5761 cagaaagtga tgccgataaa agcgatattc agcgcggtgt agagccagaa tgtacctgcc
     5821 gcgccaatgc tgtccaacag tgtcaggaat gtcgcgccga tgatcatgtt cgatacccag
     5881 tttgtcgtgg ttgaacaggt aatgccaaaa tcacgacatt tcagcggctg gatttccgaa
     5941 cacagtatcc acaccaccgg agcggcgctc atcgcgtaac cggcgataca catcatcgtc
     6001 atcccaacgg aaagccagga gagaccgctt gatgccgtac cgttatcaaa ctgcatcagg
     6061 cagtagccca acaccaatgt ccctaacgcc attacgctga aaccgatttt taacgccggt
     6121 ttacgcccgg ccttatcgac cgtaaagacg gcgataaaag tcgcgaacat aaaggtcagt
     6181 ccgaccacca gcgtagcgat catttgctgt tccgtggtgg taaagccggc cattttaaaa
     6241 atgcgcggcg catagtacat aatgatgttc atgccggtga actgctgcat tgcctgtagc
     6301 aacataccga ggaacacggc gcggcgaaca ttacggttag ctttaaataa tgcccatccg
     6361 ccctgcttga gtttgaggct ttcccgaatc tcattcagtt catcacgggc tttttccgag
     6421 gtatcgcgca gcatacgcag cacctcttcc gcttcgatat ggcgaccttt ttgcgccagc
     6481 cagcgcggac tattcggcag gaataccacc agaataatga gcaacaccgc aggcagcgcc
     6541 agcacgccca acatcgcgcg ccagttgccg ctgtagctga atgccgtatc ggataaaaaa
     6601 gccagcacaa tgcctaacgt caccatcagt tgatacatac tgatcatttt accgcgaaca
     6661 ttttcgctag ccatttcaga gagataaagc ggcgcggtat aggacgcaat ccctactgct
     6721 acgcccagta tcacgcgggc gccaatcaat acttccacgc tggaagcaaa cgccgacccc
     6781 agcgagccga gcacgaacaa aatcgcgcca gccatcaggc tatacttacg ccccagccga
     6841 aatgaaagcc agccgttaaa taatgcgcca attgccgcgc caagcatcat actgctgacg
     6901 acccattcct gcagccggct ggtcagtacg aaatggtcgg taataaaagg cagcgcccca
     6961 gcgataacgc cgatatccag accaaataac agtcccgcta ccgctgcaga aaccgaaaca
     7021 aacatattca tacgtcgtgt gtcgcgaagc gaacgcggcg ttaaagcaga gtcattaata
     7081 gagaccatat tttcctgcca ccacagagta agacatagcc tgaaagtacg ggatactctt
     7141 cctcaagtgt caggctggaa acggcataaa tatggattaa atggctacgc tatagcgata
     7201 tgtgatggat attacacttt ttaaatttaa cgccgttgcc gggtattttt tcaaaccacc
     7261 aatatttcaa taagttaaac catttatcat agctattatt taacaatata tggattaagt
     7321 taaacccaca atatggacta tgctaatgag atcataaaaa aaccctgtac gaggacaggg
     7381 ctttatcagt tttttcggcc aaagagtcga ttttcccaga aacgcatttg tcagtagcgg
     7441 attaacgcgc cagccaaccg ccatctaccg ctatggtata gccgttaata taatcagcgg
     7501 cgctggatgc caggaagact accggcccca ttaaatcgcc cggtagcccc caacgtccag
     7561 ccggaatacg gtcgagaatt tcggcgctac gttgtgcatc agcgcgcaat tgctgggtat
     7621 tattcgtgga catatagccc ggcgcgatgg cgtttacatt gatattgtgt ttcgcccact
     7681 cgttcgccat cagacgcgtt attcccatta cgccgctttt cgacgcggta taagacggaa
     7741 cacgaatgcc gccctggaag gaaagcatag acgcgatatt aataattttg ccgccgttgc
     7801 cctgggcaat aaaatatttt gccgccgcct gagacataaa gaacacgctc ttgatgttca
     7861 ggttcatgac gtcatcccag tctttttccg tgaaatcaat cgcatcttca cgacggatca
     7921 aacccgcgtt attcaccaga atatcaatat gaccgtattc cgccaccgcc cgttccagta
     7981 gcgccggaat accatcgatt tgacgcagat cggctgtcag gcttaaaaaa cgtcgtccca
     8041 gagcggtgac gcgcgcaata gtttccgtcg gttcaacaat gttaataccg acaatgtcac
     8101 agcccgcttc cgccagccct aacgccatcc cctgtcccaa tccggtatcg caccccgtca
     8161 caaccgcgac tttaccttca agagaaaatg cattcaaaat cattgttaat ccttattttt
     8221 gtcatgcctg tcacacaggc gttatcaccg gtcgcgacta gcgcagatct tgtaccgcaa
     8281 cgtgatccat gtcatcgaag acctgatttt ctcccaccat gccccaaata aacgtatagg
     8341 ctttggtgcc aacgccggaa tgtattgacc agcttgggga aataaccgcc tgttcattac
     8401 gcatcacaat atgacgggtt tcctgaggct gccccatcat atggaaaacg caactgtcct
     8461 cttccatatt gaaatagagg taaacttcca tacggcgctc atgggtatgg catggcatgg
     8521 tgttccatag attgccgggc gccagttcgg tgagtcccat actgagctga caggtttcca
     8581 gtacatccgg tacgaagtat ttattgatgg tgcgacggtt actggtgagg ttatcgccta
     8641 aggtgacggg cgcaacgtcg gcaggcgaca cttttttcgt cggataagcg gtgtgcgctg
     8701 gcgcgcagtt gtaataaaac ttcgccggtc tgctcgcctc attgctgacg aagaccagct
     8761 ctttcgcccc tttaccaata tacagagcat cacgatgacc aatgtcatgg cgctgcccgt
     8821 caacgataat ggcgcccgcg ccgccaatat taatgacgcc cagctcgcgg cggtccagta
     8881 atcgggaaac gccaagctgt ttacctactt ctccgccgat ttcaacggaa tggctgacgg
     8941 gcataatgcc gccgacaata atacggtcga tatggctgta gaccatcgta tattcatcag
     9001 cgacaaaaat attttctatt aaaaactcgc gtcgcagcgc ctgggtgtcc agcgttttag
     9061 cgtgctcgct atggatactt tgccttacgt ccacttttcc ctccaatgat aaatcgatcg
     9121 caacggcata aaatcaaaac actgttttga tttatttaac ggcatcatag tcgcctggat
     9181 aaaggttttc aacaataaat aaaacaacgt ttcattttta tgtctggtta tttttaaaac
     9241 tgctgtagcg atcacgatcg gcgctaaaac ttacgcattt gtctgatttt cagacatgcg
     9301 cgccagatgc tgtatgcggt tacccagata aaaattggag cttgttttag aacgaggtct
     9361 gatgtgcgaa ttgaattaaa agcggtacgc gtctgcaatg cccgccgcgg caagaagttc
     9421 tgcgctataa cgaaaaaggg gggtctgtca ctggctttgc cctcgtgata gagggctttt
     9481 tatgacggaa tactgaagca ggaaaagggt ggctggcgta ggatcagtcg cgttcaatgg
     9541 ttaaagcaac gccctggccg ccaccgatac acagcgtcgc cagacctttt cgcgcgtcgc
     9601 gtttaaccat ttcgtgcacc agtgaaacca gaattcgaca accggaagcg ccaatgggat
     9661 gccccagcgc aatcgcgccg ccattaacgt ttacccgtcg ctcatcccat tccagcattt
     9721 ttcctaccga caacgcctgg gcggcaaacg cttcgttggc ttcgataagg tcgacctccg
     9781 tcagttgcca gccggcacgc tccagacagc gccgggtagc atataccggc gcaatcccca
     9841 ttagcgcagg atcgacgccg acgctggcaa acgcgcggat gcgcgccagc accggcagcc
     9901 ccagcgcctg ggctttcgtc tcgctcatca tcatcaccgc ggcggcgcca tcgttgattg
     9961 aagaggcatt acccgccgtc accgaaccta aactatcaaa cgccggatgc agcagggcta
    10021 acccctccgc actggcgtcg gcccgcggtt gttcatccgt atcgacaatt gcggtctgcc
    10081 cattacgttg cgtgacgatg gggacaatct catctttaaa acgtccggta tcaatcgcgg
    10141 ccctggcttt ttgttgcgaa ctgagcgcat aagcatcctg taactcgcgg ctgatgccat
    10201 attcccgcgc caggttttct gccgtcacgc caatgtgata atcgttgaag gcatcccata
    10261 agccatcatg taccagacta tccaccagat tgtcggcatc aggcaacgcg ccggtacggc
    10321 tgtcattgag gacatgcggc gcacggctca tattctcctg cccgcccgca ataacaatgt
    10381 ccgcttcgcc gcactgaata gcctgcgtcg ccaggtgcaa cgcttttaaa ccggaaccac
    10441 aaacgtcatt aatggtaata gcggaaacgg tagtcggcag ccctcctttg atggctgact
    10501 ggcgcgccgg attctgcccg gcgccagccg tcagtacctg accgaggatg acctcatcga
    10561 tagcattagc gtccacgccg gtgcgctcaa ttaacgcttt tacgaccata ctccccagct
    10621 cgacggcgga atgacgggcc agcgttccct gaaaacagcc gatgggtgtc cgtaaagccc
    10681 ccactatcac aacctctttc attaccacct cagcgcaaaa tgacaccgcc atagtagagc
    10741 attgttaaaa ttagttatct tgattgttta aaaaaagtga gttttatcac aaaggaaatg
    10801 acgctgattt gacggtggcg cagcttattt ctgctgtaaa tggtagcgaa gccagttccc
    10861 cgccgttccg ggcggcgtct tcttgttcca caacaaatca atagcaatcg ccctcggcca
    10921 gccaggaaca tccagctgcg ccagcggttt ttccgccgca aactcttcca ccagcgcgca
    10981 gggcaatacg caccagccaa atccctgaac cgccatgctc aacagcaata aatagtttgg
    11041 cgctgaccag gccgggccgc gcgtaatgtt ggcgttagag tcaaggtagg tattcagacg
    11101 cagctcgcgc caggtatgca gttgctccca ttgcaggttc gtctgcgacg ccaacggatg
    11161 cgtggtcgcc acataaaccc ccatccagct ttgaacaagc agacgcgtcg cgccaatgtc
    11221 tgtgggatag ttatcacgcg cttcaatcag gcctatctgg gcgcgccctt tttgcagcag
    11281 gtcgatgaca tcatcatttt ctccgatcaa acattcaaac tcggtatgcg ggaattgacg
    11341 atcaaactgc gccattaact cttccagact gtcagggtgc agggtatcag agaggacgaa
    11401 cgtgagcctt gtctccgtct cgccggataa cgtcagcgcc acctcatcca gacggtcgct
    11461 cgccgataaa atagcctgaa catagctaag cacccgtttt ccttcttcgg tcagaacggg
    11521 ctggcgcgat gatcgatcaa ataatgaaaa tcccagatcc gcctccagat gcgcaatggc
    11581 ggtactaatg gtggactggc ttttacgcag gcggcgcgcc gccgcagaaa acgagccgca
    11641 agagacggcc tcaacaaatg ccattaacgc ttcaggtgag taacgcataa cctatctact
    11701 tt
//
LOCUS       DAJVKX010000138        11574 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.138, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000138 DAJVKX010000000
VERSION     DAJVKX010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11574
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.138"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            165..545
                     /locus_tag="OPY25_003745"
     CDS             165..545
                     /locus_tag="OPY25_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HCS0929247.1"
                     /translation="MDKDYINDGSLSEKWKYRFSFYDQHGFPGFWKVSPEYKQAFKAL
                     KPRQRLTIQINFIAFFFSWIYLFVLGLWKKAIIVILLGIVAIFIGALIGVNILGLVVA
                     AYVGVNTNKWFYEKEVKGINTWSL"
     gene            complement(594..1544)
                     /gene="corA"
                     /locus_tag="OPY25_003746"
     CDS             complement(594..1544)
                     /gene="corA"
                     /locus_tag="OPY25_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HCS0929248.1"
                     /translation="MLSAFQLEKNRLTRLEVEESQSLIDAVWVDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDEDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQAMVDGNAYELLLDLFETKIEQLADEIENIYSDLEKLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            complement(2016..4178)
                     /gene="uvrD"
                     /locus_tag="OPY25_003747"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             complement(2016..4178)
                     /gene="uvrD"
                     /locus_tag="OPY25_003747"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HCS0929249.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNMLVLAGAGSGKTRVLVHRIA
                     WLLSVENNSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQMRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWVRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAQT
                     IRLEQNYRSTSNILSVANALIENNNGRLGKKLWTDGVDGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNDEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGWRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPLAENDTGYKLGQRVRHAKFG
                     EGTIVNLEGSGEHSRLQVAFQGQGIKWLVAAYAKLETV"
     gene            complement(4314..5030)
                     /gene="yigB"
                     /locus_tag="OPY25_003748"
     CDS             complement(4314..5030)
                     /gene="yigB"
                     /locus_tag="OPY25_003748"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HCS0929250.1"
                     /translation="MRFYRPLGRIAALTFDLDDTLYDNRPVILRTEQEALAFMQNYHP
                     SLRSFQNVDLQRIRQAVREAEPEIYHDVTRWRHRAIEQAMRDAGLSAQESIAGANAAM
                     MHFAKWRSQIEVPQATHETLQQLAKKWPLVAITNGNAQPELFGLGDYFKFVLRAGPDG
                     RSKPFSDMYFLAAEKLHVPIGEILHVGDDLTTDVAGAIRCGMQACWIKPENADLMRTQ
                     DSRLLPHIEISRLASLTSLI"
     gene            complement(5030..5932)
                     /gene="xerC"
                     /locus_tag="OPY25_003749"
     CDS             complement(5030..5932)
                     /gene="xerC"
                     /locus_tag="OPY25_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCS0929251.1"
                     /translation="MTEVALSLDVSRFLRYLGVERQLSPITLQNYQRQLDAIIALAGE
                     TGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLSALRSFFDWLVSQGELKANPAKG
                     VSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIK
                     HLDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRIS
                     ARNVQKRFAEWGIKQGLNSHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQI
                     YTHLDFQHLASVYDAAHPRAKRGK"
     gene            complement(5929..6636)
                     /locus_tag="OPY25_003750"
     CDS             complement(5929..6636)
                     /locus_tag="OPY25_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HCS0929252.1"
                     /translation="MKQPEEELQETLTELDDRAVVDYLRHHPEFFIRNAHAVEAMRVP
                     HPVRGTVSLVEWHMARARNHINVLEENMTLLMEQAHANESLFYRLLHLQSRLVAADSL
                     DEMLMRFHRWARDLGLAGATLRLFPDRWRLGAPSRYTHLALNRQAFEPLRIQRLGQSQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMMGSDGDLGVILFSSRDPHHYQPGQGTQLLQ
                     EIALMLPELLERWIKRV"
     gene            complement(6633..7457)
                     /gene="dapF"
                     /locus_tag="OPY25_003751"
     CDS             complement(6633..7457)
                     /gene="dapF"
                     /locus_tag="OPY25_003751"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCS0929253.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLSDRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLSVTEDELVRVNMGEPNFEPAQVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDNVDTAAVETLGPVLESHERFPERANIGFMQVVRREHIRLRVYERGAGETRACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAAHIYDGFIHL"
     gene            complement(7494..7697)
                     /locus_tag="OPY25_003752"
     CDS             complement(7494..7697)
                     /locus_tag="OPY25_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0929254.1"
                     /translation="MKNVFKTLAVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKKVDS
                     QTQSTMPDKNDRATGDGPSQVNY"
     gene            7883..9892
                     /locus_tag="OPY25_003753"
     CDS             7883..9892
                     /locus_tag="OPY25_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929255.1"
                     /translation="MQYRNLFCLFSLSLLLPPAWGCRLSEPPHNVYQRQGSGVVYLQP
                     EEENNLSLPEVNFKRLRRLPNSLINPATQDEWDREPPLTDLTTDYVHTSAQAIFPRFS
                     YYSDGRVILYGGKIMRNPPGTPSVDVASFRAFGKVGVDKNSLYDEGKRTDDNGGENRV
                     NLQSLRKVEFSSQWKPDLLGLTLRDDRFLYVDGHRLSDPDSFTVLAQKSWDQRGKFSA
                     TFNPCIAVPFGPWDTLARTRTKIIINGDQLDADPDTFSVVRWMPGSLLTWRDKNGLHR
                     HVLNQNNLNWDMQIEKHCDAFNLQEKRVLWRKGPGCKFAEIPGLDPEQFHPLSNAVAQ
                     SQDRLYAIRKTEFGENQLDVVTLDNPNLVIDKRFNAGRYHGYLLTKTRSDFKEEDGLQ
                     VFESAGPLILMDYHVPDETEAHLGDSPHYKKWYARDDRYVYAFDGAQLWRYPTPNPKA
                     LRMKWQTTHSGYGYWVDYRIAQLDGALMEDGSFIATGIPRDPSVKTAYVKTDGTFDIG
                     KTAVRWRKVLSPDGEWGRWQTIPNVDPSQFHLVNDRIAQYKDRLYIARLSPFGEDQLE
                     TLELDSTAPFLNQKINAGKEHGYFMHNSQQAQDIQVFSINGPLKVTERFAYDNRYVYT
                     WIGSQIYRTASLCPDKTLNLNQNMYSDNKDIIIITQAQECQKSRR"
     gene            9871..10260
                     /locus_tag="OPY25_003754"
     CDS             9871..10260
                     /locus_tag="OPY25_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 family protein"
                     /protein_id="HCS0929256.1"
                     /translation="MPKITSLSRFARLIKHLKNALRGVGIGSCIYVIVESVMHGTING
                     VEAAGVLTISAVLGLLSALLDIKAKPRAPLILLHFLLCGGCVALMVAMLSVLNHFPVN
                     ASVILITSALFIVIYLPLGFILYRSQR"
     gene            10330..10650
                     /gene="cyaY"
                     /locus_tag="OPY25_003755"
     CDS             10330..10650
                     /gene="cyaY"
                     /locus_tag="OPY25_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HCS0929257.1"
                     /translation="MNDSEFHRLADALWLTIEERLDNWDGDSDIDCEINGGVLTLSFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWVCDRSGETFWDLLEQAATQQAGEK
                     VSFR"
     gene            complement(10722..11084)
                     /locus_tag="OPY25_003756"
     CDS             complement(10722..11084)
                     /locus_tag="OPY25_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929258.1"
                     /translation="MFFVITHHIDVLPLATLPTHETCPYCNNQDVWLIIRQKRTRTCG
                     LSQARKRDKFGLAICNHCSNEIKEKRWSPALRQLFTEQKSLFNLTFWQRYGFWVGWLS
                     VWPALFLATWLYFTFRGW"
     gene            complement(11096..11455)
                     /locus_tag="OPY25_003757"
     CDS             complement(11096..11455)
                     /locus_tag="OPY25_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014341494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929259.1"
                     /translation="MIAGASAYWYSAFSGKPQLTLNQEGVTLHTTRLPIVYWHEIDYV
                     GERVSDNTPVLAIFVKDIELYCQRITNEKMRNNFLSLLNKHGSNRVMNISLNDLDYDS
                     DELQDIFKMAVARNLEQ"
BASE COUNT         2765 a         3169 c         2894 g         2746 t
ORIGIN      
        1 ttgtaatcta tattgcctcc ttcgtgataa tggttgctga agatttcgct tgcgatggct
       61 ttggtatgcc tctttttcta atctggtatt ttgcaacctt ttctctgcta cttctggccc
      121 ccccggattc gaattcactc aacaagtaat ttaatggagt ttacatggac aaggattata
      181 ttaatgatgg ttcgttatct gaaaaatgga aataccgttt ttcattttac gatcaacatg
      241 gtttccctgg attttggaaa gtaagcccag aatataaaca ggcatttaaa gcattaaagc
      301 cccgacaacg gttgactatt caaataaact ttattgcctt tttcttctca tggatttatt
      361 tgtttgtact gggtctgtgg aaaaaagcaa ttatagttat tttattaggg atcgttgcaa
      421 tatttattgg agcattaatc ggcgttaaca tacttggact tgttgtcgca gcttatgtcg
      481 gcgtcaatac aaataagtgg ttctatgaaa aagaggttaa aggtatcaat acttggagcc
      541 tgtaactttt cagggtggtt cagccgcagc tgaatcaccc tggccttaat gtcttacagc
      601 cagttcttgc gcttaaagta cagatacggc gcaagccccg ccagaatcat aaagataatc
      661 gcgcctggat aaccaaagct ccacttcagt tccggcataa actcgaagtt catcccatag
      721 ctggaagcga ccagcgtcgg cggcaggaac accacggaaa ccaccgagaa gattttgata
      781 atgcggttct gttcaatgtt gatgaaaccc atcgccgcct gcatcaggaa gttcaccttc
      841 tggaacagcg attcattgtg cggtagcaga gattcgatat cgcgcaggat ctcacgcgcc
      901 tgctccagct gtccgcccgg taagcgcgcc ttgcgcacca ggaagttcag cgcgcgctgg
      961 gtatccatca gacacaggcg taccttccag ccgatatctt ccagttccgc cagcgtggag
     1021 agcgcttcgt cgtattcatc gccctgatgc ccttccataa tgacgcggct cagtttttcc
     1081 agatcgctgt agatgttttc gatttcatcc gccaactgtt caattttggt ttcgaacaga
     1141 tcgagtagta gttcgtaagc attaccatcg accatcgcct ggctgcgggc gcgcatacga
     1201 tacaaacgga aggcgggcag ttcgcgttca cgcagcgtaa acagacggcc atcgcgaata
     1261 gtgaatgcca ccgtagagtt accggcatga tcttccgcat cttcgaagaa gaagaaggag
     1321 tggatatgca gtccgtcttc gtcttcaaag aagcgcgcgg atgcttcgat atcttccagt
     1381 tcaggacgcg tcgccagact ctggcccagc tcagattgta cgcgcaatcg ctcgtcgtcg
     1441 tccggttcga ccaaatcgac ccatacggca tcaatcaggc tttgtgactc ctcgacttcc
     1501 agccgggtca gtcggttttt ttccagttga aatgcgctca gcatgaccgg gactcccaat
     1561 gcgtaaaaat atcggacagt tcagatgggc acacagaaac aaattgggtt tcagaccatt
     1621 aaacagcctg actcaacgcg acgggaaaaa atgaaaggtc gctgacaacc gctaaggcta
     1681 tcagcaaaaa gggatagcct taggagttga tcctggatga caggataatg agccagtatc
     1741 tactgggtgt gtccaaggcg aatgtcctct tagcgtaatc gtgggcgcat gttacgccag
     1801 caaaaatttg ccgtcaacac gcaacgaaac gcgaaaaagc aataatttcc ccttatgcag
     1861 aaaggttagc agagtgagag tatttatcta tgatttcaga atattaacat caatatatcg
     1921 ccggatggcg gcttcgcctt atccggccta caaatcaaaa tgttagccag cgcgtaggcc
     1981 ggataagagg tgccatccgg caatatgaga gccggtcaaa ccgtttccag cttcgcatac
     2041 gcggcaacca gccatttgat cccttgcccc tgaaaagcca cctgcaaccg gctatgttcg
     2101 ccgctgccct ccaggttgac aatagttccc tcgccgaact tcgcatggcg cacgcgttgg
     2161 ccgagtttgt agcctgtgtc gttttccgcc agcggcgttc ccattcgttg atggctcacc
     2221 ggacgactga cggtggcgcg cagacggacc tcttccacgc actcctccgg caactcgccg
     2281 atgaaacgcg acgggcgatg ataaacctct ttaccataca gacggcgagt ttcggcatag
     2341 gttagcgtca gtttctgcat ggcacgggta acgccgacgt aggccagacg acgctcctct
     2401 tccaaacgcc agccctcatc cagcgacatc tggctgggga acatcccctc ttccatcccg
     2461 acgataaaca cctgcgggaa ctccagccct ttggccgagt gcagcgtcat cagctgtacc
     2521 gcatcctgcc aggtatccgc ctgcccctcg cccgcttcca gcgccgcgtg agagaggaag
     2581 gcctgcaatg gcattaaatc ttcatcttcg tcgttgtagc tgaactgccg cgttgccgtc
     2641 accagttcct ctaagttttc gatgcgcgtc tggcctttct cgcctttttc ttgctcatac
     2701 atggtgcgca ggccggaatc tttgatcacc cggtcagtct gcacatgcag cggcatgtcg
     2761 gcggtttcct gcgccagggc gtcgatcagt tccataaagc gttgcagcgc gctggccgca
     2821 cgcccggcca gggctttttc ctgtaacaat tcacggcacg cctgccacaa tgttagctgg
     2881 cgatcgcgcg aggtctggcg caccacgtcc agcgtgcggt cgccgatacc gcgcgttggg
     2941 gtattcacca cgcgttcaaa ggcggcatca tcgttgcgat tggcaatcaa acgcagataa
     3001 gagagcgcat ctttgatctc ctggcgttcg aagaagcgca taccgccgta aatgcggtac
     3061 ggcatactgg cctgtaataa cgcttcttcc agcacgcgcg actgggcgtt gctgcgataa
     3121 aggatggcgc attgcgcaag cgcgccgccg ttgtcctgcc aggttttgat acgattaacc
     3181 acaaagcgag cttcatccag ttcgttgaaa gcgcagtaca gcgatatcgg ttcgccgtca
     3241 acgccgtcag tccacagctt tttgcccaga cgcccgttgt tgttttcaat cagggcgttc
     3301 gccacgctaa gaatgttgct ggtcgagcgg taattctgct ccagacgaat ggtctgcgcg
     3361 ccggggaaat cattgaggaa gcgctggatg ttctctacct gggccccgcg ccagccgtag
     3421 atcgactggt catcgtcgcc gacaatcatc actttaccgg tatcgcccgc cagcagacga
     3481 acccaggcgt actgaatgtt gttggtatcc tggaattcgt ccaccagaat gttagtaaac
     3541 cgctcgcgat agtgttgcag gatgtgcggc ttgttcagcc atagttcatg agcgcgcagc
     3601 agtagctcgg cgaaatccac cagaccagcg cgatcgcacg cttcctgata ggcctgatac
     3661 accttctgcc aggtctgttc caccggattg ccatagcttt ggatatggtg cgggcgtagc
     3721 ccttcgtctt tctggctatt gatgtaccac atcgcctgac gcggcggcca ctgcttctca
     3781 tcaagattca tcgccttaat caggcgttta agcaaacgca tctgatcttc gctgtcgaga
     3841 atctggaaat cctgcggcaa attagcgtcc atatgatgcg cgcgcagcag gcggtgcgcc
     3901 agaccgtgga atgtccctac ccacattccg ccctggctgg tccccatcaa ctggccaata
     3961 cgatggcgca tttccgccgc cgctttgttg gtaaaggtca ccgccatgat ggagtatggc
     4021 gagttgtttt ctacgctcag taaccaggcg atacggtgca ccagcacgcg ggttttcccg
     4081 cttcccgcgc ccgccagcac cagcatgttg ctacgtggcg cggccaccgc ttcgcgctgt
     4141 ttatcattaa ggctgtcgag caggtaagaa acgtccattg gcaccgccgc gtaaaaacat
     4201 gaaaactaaa aacgcccggt ggcgcttcgc ttaccggggc tacttatcgt agggcggata
     4261 agcatagcgc catccgccag aataactggg aatttataca gaactactgg tgattatatc
     4321 agcgaggtga gagatgccaa ccgcgaaatt tcgatatgcg gcagtaaacg gctgtcctgc
     4381 gtccgcatca ggtcggcatt ttcaggttta atccagcagg cctgcatccc acagcgaata
     4441 gcgccagcca catcggtagt cagatcgtcg ccgacatgca ggatctcgcc gatcggcaca
     4501 tgcagttttt ccgccgccag gaaatacatg tcgctaaacg gtttggaacg tccatccggg
     4561 ccggcgcgca gtacaaactt aaagtaatcg ccgaggccaa acagttccgg ctgggcattg
     4621 ccgttagtga tcgccaccag cggccatttt ttcgcaagct gctgtaacgt ctcatgggta
     4681 gcctgcggaa cctcaatctg gctgcgccat ttggcaaaat gcatcatcgc cgcattcgca
     4741 ccggcaatgg actcctgcgc cgataatccc gcatcccgca tggcctgctc tatcgcgcga
     4801 tggcgccagc gggtaacgtc atgatagatt tccggctccg cttcacgcac cgcctgccgt
     4861 atccgctgta aatcgacgtt ttgaaacgaa cgtagcgacg ggtgataatt ttgcataaaa
     4921 gcgagcgctt cctgctcagt acgcaaaatc accggacggt tatcataaag ggtatcatcc
     4981 aggtcaaagg tgagcgcggc aatacgcccc aaaggccggt aaaaacgcat tatttccccc
     5041 gtttagcgcg cggatgcgcc gcgtcgtaca ctgaagcaag atgttgaaaa tcaagatgag
     5101 tataaatttg ggtggtggaa aggttggcat gacccagcag ctcttgcacg ccgcgcagat
     5161 cgccgctcga ttccagcata tgggtcgcga acgaatggcg cagcttatgt ggatgcacgt
     5221 ggctgtttag cccctgcttt atgccccatt cggcgaaccg tttttggaca ttgcgcgcgg
     5281 agatacgctt gccgagcttc gacaggaata acgcctcttc atcgctggcg aacaggccgc
     5341 gcagatccag ccagtgctca atccacgtca ccgcgttacg gccaatcggc aggcgtcgct
     5401 ctttgctgcc tttacccatt acccacactt ctccggtatc gagatcgagg tgctttatat
     5461 ccaggccaac cagttcggat aaacgcagcc ccgcgccgta catgacctcc agcatcgccc
     5521 ggtcacgtac ggcgagcgga tcgttaagat cgatgtccag caggcggtta acgtcgtcga
     5581 catcaatatt tttcggcaga tgacgcggcg ctttcggtgc ggagacgccc ttcgccgggt
     5641 tagctttcaa ttcgccctga ctgactaacc agtcaaaaaa gcttcgcaat gccgagagac
     5701 gtagcgccag actggcaggg ccaagccctt tacgccgact gcgcaccgca aaactgcgca
     5761 caatcgcagc gtcacattgt tgccagcttt tcagcccggt ttctccggct aaagcgataa
     5821 tggcatcaag ctgacgctgg tagttctgca gggtaatggg gctaagctgg cgctccacgc
     5881 ctaaatagcg caggaaccgc gagacatcca gagaaagcgc gacctccgtc atacgcgttt
     5941 aatccagcgt tccagcagtt ccggcagcat cagcgcgatc tcctgtaaaa gctgcgtccc
     6001 ctgccccggc tgatagtggt gcgggtcacg gctgctgaag agaatcaccc cgaggtcgcc
     6061 atcgctgccc atcatcgaca tggctaccga ccctacagcc ttcgcctccg gcaagaccac
     6121 cagcagttcc gggccgttta gcgggccaag ataatgctgc gactgtccca gtcgttgaat
     6181 acgcagcggc tcgaaggcct gacggtttaa agccagatgc gtatagcgcg atggcgcgcc
     6241 aagacgccac cgatccggga acaaacgcag cgtcgcgccg gcaagcccca aatcgcgcgc
     6301 ccagcggtga aaccgcatca gcatctcatc cagactatcc gcggcgacca gacggctttg
     6361 cagatgcagc aagcgataaa acaggctttc attggcatga gcctgttcca tcagcagcgt
     6421 catattttct tcaagcacat tgatgtgatt acgcgcgcgg gccatatgcc actcaacgag
     6481 cgaaaccgtt ccccgcacgg gatgtggaac acgcatcgct tcaacggcgt gggcgttacg
     6541 gataaaaaac tcagggtggt ggcgcaggta atcgacgacc gctcgatcgt ccagttccgt
     6601 gagcgtttcc tgtagttctt cctctggttg cttcataaat ggataaatcc gtcgtagata
     6661 tgtgccgccg gaccagtcat gtataacgga tgacccggac ctttccaggc gatatccagc
     6721 cgaccgcccg gtaattccac gcgtacttct tcagccagca gcccctgctg aatccccacg
     6781 gcaacggcag cgcacgcgcc gctgccgcac gcgcgggtct cccctgcgcc gcgttcatag
     6841 actcgcagcc ggatatgctc acgtcttaca acctgcataa aaccaatgtt ggcgcgttcc
     6901 ggaaaacgct catggctttc cagaaccggc cccagtgttt caacggccgc cgtgtcgacg
     6961 ttatcaacct gaatgacaca gtgcggattg cccattgaaa ccacgccgca cagtatggtc
     7021 tgttccgccg ctcgcataat atacgtcttt tccgctttgt tggcgcgaaa aggcacctgc
     7081 gcgggttcaa agtttggctc ccccatgttc acccgcacca gttcatcttc cgtgacgctc
     7141 agtaccatcc ggccattcgc ggtactgacc cgaatatcgc gtttattggt tagccctttc
     7201 aggcgaacaa atcgcgcgaa acagcgcgcg ccattgccgc actgcgagac ttcactgccg
     7261 tcggcgttga agatgcggta atgaaagtcc aactcaggat catagggcgg ctcaaccacc
     7321 agcagctgat cgaaccctac gcccaagtgt ctgtcggata gccgacgaat cagttccggc
     7381 gaaaaaaaga cattctgcgt taccgcgtcg acgaccataa aatcgttgcc aaggccatgc
     7441 attttagaga attgcatcat tcactccgtt cacgcgggga cagaaaacta tcctcagtaa
     7501 ttgacctggg acgggccatc tcccgttgcg cgatcgttct tatcgggcat cgtggactgc
     7561 gtttgcgaat cgactttttt cgtcggcggc ggcgcatttt tatcggctgg cgggaaataa
     7621 agcggccctt tcaaaccgca gcccgtcagg ctgaacagag tcagaagtac agcgagtgtc
     7681 ttaaacacgt ttttcattat ggattgcctg taagttcatg ctttctattt tctatcatcg
     7741 caggagaagg agtaaaagca agcgtttagg ggctctttat aaaatctgaa aagcggcgcg
     7801 ttgccatgat tattgcgcat ttacatcagg aaacatgctt tgctcatcac tttaggttta
     7861 cgtaccacgt ccggatgacc ttatgcaata tcgtaatttg ttttgccttt tttcgctttc
     7921 acttctgctg cctcccgctt ggggatgccg gctgagtgaa cctccgcaca atgtttatca
     7981 acggcaaggc agcggcgtgg tttatctcca gccagaagag gagaacaatc tttcgttgcc
     8041 ggaggtgaat ttcaaacgcc tgcgtcggtt acccaattca ttgattaacc cggcaactca
     8101 ggatgagtgg gacagggaac cgccgctcac cgacctgacg accgattacg ttcataccag
     8161 tgcgcaggct atcttcccgc gcttttccta ctacagcgac ggacgcgtta ttctgtacgg
     8221 tggaaaaatc atgcgtaatc cgccggggac gccatcggta gatgtcgcct catttcgcgc
     8281 ctttggcaaa gtcggcgttg ataaaaatag tctctatgac gaaggcaaac gaacggatga
     8341 caacggcggc gaaaaccgcg ttaatttaca gtcattgcgt aaggttgaat ttagcagcca
     8401 gtggaaacca gacctgttgg gcttgacgct gcgcgacgat cgctttcttt atgtcgacgg
     8461 gcatcgcctg agcgacccgg acagtttcac cgttctggcg caaaagtcct gggatcagcg
     8521 cggtaaattt tccgccacat ttaatccttg tatcgccgtc ccctttggtc cctgggatac
     8581 gctggcccgc acacgcacca aaatcatcat caacggcgac caactggacg ccgacccaga
     8641 caccttttcc gtggtgcgct ggatgcccgg ttctctattg acctggcgcg ataaaaacgg
     8701 cttgcaccgt cacgttctca accagaacaa tctgaattgg gacatgcaaa ttgaaaaaca
     8761 ctgtgatgcg ttcaacctgc aggaaaaacg cgtgctgtgg cgtaaaggac cgggatgcaa
     8821 atttgccgaa atccccggcc ttgacccaga acagtttcat ccgctcagta atgcggtggc
     8881 gcagtctcag gatcggcttt atgccatcag gaaaacggaa ttcggcgaaa accaactgga
     8941 tgtcgtcacg ctggataacc caaatctggt aatagacaag cgttttaatg ccgggcggta
     9001 tcacggttat ttactcacta aaacgcgatc cgactttaag gaagaagacg gattgcaggt
     9061 attcgagtcg gctggcccgc ttattctgat ggactatcac gttccggacg agacagaagc
     9121 gcatctgggc gacagcccac attacaaaaa atggtacgca cgcgacgatc gctatgttta
     9181 cgcgtttgat ggcgctcaac tgtggcgcta tcccacgccc aatcccaaag ctctacgcat
     9241 gaaatggcaa acaacacact caggatacgg ctattgggtg gattaccgca tagcccagtt
     9301 agatggcgct ctcatggagg atggctcttt tatcgccacg ggtatcccgc gcgatccttc
     9361 cgtaaaaaca gcctatgtta aaaccgatgg cacctttgac atcggcaaaa cagcggttcg
     9421 ctggcgcaag gttctgtcac ctgacggtga gtggggtcgt tggcaaacca ttcccaacgt
     9481 tgacccgagt cagtttcatc tggttaacga tcgcatcgcg caatataagg accggctata
     9541 cattgcgagg ctctcacctt ttggcgaaga ccagttggaa acgctggaac tggatagcac
     9601 agcccccttc ctgaaccaga aaattaacgc cggaaaagag cacggctact ttatgcataa
     9661 tagccagcag gctcaggata ttcaggtctt tagcatcaat gggccgctaa aagtcaccga
     9721 gcgttttgcg tatgacaacc gctatgttta tacgtggatt ggtagccaga tttaccgaac
     9781 agcatccctc tgcccggata agacgctcaa tttgaatcag aatatgtact ccgacaataa
     9841 agacatcatc atcataacgc aggcgcagga atgccaaaaa tcacgtcgct aagccgtttt
     9901 gcgcgcttga ttaaacattt gaaaaacgcc cttcggggcg tggggatcgg ttcatgcatt
     9961 tacgtcattg ttgaaagcgt tatgcacggc acgataaacg gtgttgaagc tgccggagtc
    10021 ctgacgataa gcgcggtact cggtctgctt agcgctcttt tggatatcaa agcaaagccg
    10081 cgcgccccct taatcctgtt gcattttctc ctctgcggcg gctgcgtcgc actgatggtg
    10141 gcaatgctgt cggttctgaa ccatttcccg gttaatgcgt ccgtcatact tatcaccagt
    10201 gcgctattta tcgtcattta tctaccgctg ggttttatcc tttaccgctc acaacggtaa
    10261 ttcgtatcgg ttccagaagc tgacgcttcc ccttatactg gcgctatcac tcaatagcgg
    10321 gataaaacaa tgaacgacag tgaatttcat cgcctggctg acgccctgtg gctcaccatt
    10381 gaagaacgcc ttgataactg ggacggcgac agcgatatcg actgtgaaat caacggcggc
    10441 gtgctgaccc tcagctttga gaacggcagt aagatcatta ttaaccgtca ggagccgttg
    10501 caccaggtgt ggctggcaac caaacagggc ggctatcatt tcgatctgaa aggcgacgag
    10561 tgggtttgcg atcgcagcgg cgaaacgttc tgggatctgc tggagcaggc ggcgacgcag
    10621 caggcgggtg aaaaggtgag tttccgttaa gttttcaatt ccgcaggaga gccagaagaa
    10681 tagcgctttc ctgcgtatat ttaacgagat atgcggtcgt attaccaacc ccggaatgtg
    10741 aaatacagcc aggttgccag aaacaacgcg ggccatacac tcaaccaacc aacccaaaaa
    10801 ccgtagcgtt gccaaaaggt taggttaaat agtgacttct gctcggtaaa aagttgacgt
    10861 aacgctggtg accaacgttt ttccttgatt tcattgctgc aatgattgca tatcgctaaa
    10921 ccaaacttat ctctttttct cgcttgagac agaccacatg tacgggtcct tttttggcga
    10981 ataatcaacc atacatcctg attattacaa taagggcatg tttcatgtgt gggtagggtt
    11041 gccagaggca gcacatcaat atggtgagta ataacaaaaa acatatatct ctaccctatt
    11101 gttccaggtt tctggcaaca gccattttaa aaatatcctg taactcatct gaatcataat
    11161 cgagatcgtt tagagagata ttcatcacgc gattacttcc atgcttattc aataatgaca
    11221 gaaaattatt acgcattttc tcattagtaa ttcgctgaca ataaagctca atatctttga
    11281 caaaaatggc cagcacaggc gtattatcgc taacacgctc accaacatag tcgatttcat
    11341 gccagtaaac tattggtagc ctggttgtgt gtaatgttac tccctcctgg ttcaacgtta
    11401 gctgtggctt tcctgaaaag gcggagtacc agtaagcact tgcgcctgct atcatgagga
    11461 ttatgaaaaa aacacacatc atctttagca taatactata atttagaaag aggctcatca
    11521 taaaaactat agctaacact gaataaaaca gagctaattt tatttgtcgt ttct
//
LOCUS       DAJVKX010000139        11401 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.139, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000139 DAJVKX010000000
VERSION     DAJVKX010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11401
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.139"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            411..866
                     /locus_tag="OPY25_003758"
     CDS             411..866
                     /locus_tag="OPY25_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4385 domain-containing protein"
                     /protein_id="HCS0929260.1"
                     /translation="MAIKPFNYQQDFSSIDFRQQPELYQVGRGEQGGLLVEPYKSEIL
                     PFWRYKDEASAMKSAEQIYQLFEAYRQQDDFVGMDMARKFIQMGYTRARRYANYKGGK
                     KYAEDGSLNTRGNDPIKAAAATVFKGWWDKIRQDEDYLKRKRQHQARWG"
     gene            970..2271
                     /locus_tag="OPY25_003759"
     CDS             970..2271
                     /locus_tag="OPY25_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929261.1"
                     /translation="MAEIIQRIDKNNAEAPEMRRHIWAIVGASSGNLVEWFDFYVYSF
                     CSLYFAHIFFPSSNTTTQLLQTAGVFAAGFLMRSIGGWLFGRIADRRGRKASMLISVC
                     MMCMGSLVIACLPGYDTIGTWAPALLLIARLFQGLSVGGEYGTSATYMSEVALEGRKG
                     FFASFQYVTLIGGQLLALLVVVILQQVLEDAELRAWGWRIPFALGAVLAVVALWLRRQ
                     LDETSKHETRALKEAGSLKGLWRNRKAFLMVLGFTAAGSLCFYTFTTYMQKYLVNTAG
                     MHANVASGIMTAALCVFMLVQPLFGALSDKIGRRTSMLCFGALATLFTVPILSALQNV
                     TSPYAAFALVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANALFGGSAEY
                     VALSLKSVGMESSFFWYVTAMAVLAFLVSLMLHRKGKGLRL"
     gene            complement(2268..2591)
                     /locus_tag="OPY25_003760"
     CDS             complement(2268..2591)
                     /locus_tag="OPY25_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HCS0929262.1"
                     /translation="MRVLIPFTVLFLSGCSHLANDHWSGQDKAQHFMASAMLSAAGNE
                     YARHQGVSPDRSAAIGLMFSLSLGASKELWDSRPEGSGWSWKDFVWDVAGATTGYAIW
                     QMARY"
     gene            complement(2636..3991)
                     /gene="pssA"
                     /locus_tag="OPY25_003761"
     CDS             complement(2636..3991)
                     /gene="pssA"
                     /locus_tag="OPY25_003761"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HCS0929263.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYTPATFRETLLEKI
                     ASATQRICIVALYLEQDDGGKGILDALYAAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRLAQENPGIDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYQLIRNRQMADIMFDWVTQNLMNGRGVNRLDNTQRPKSPEIKNDIRLY
                     RQELRDASYHFQGDANDEQLSVTPLVGLGKSSLLNKTIFHLMPCAEHKLTICTPYFNL
                     PAVLVRNIIQLLRDGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLLTGNNLNPRAWRLDLENAILIHD
                     PKQELAPQREKELELIRTHTTIVKHYRDLQSIADYPIKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            complement(4106..6766)
                     /gene="pat"
                     /locus_tag="OPY25_003762"
     CDS             complement(4106..6766)
                     /gene="pat"
                     /locus_tag="OPY25_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HCS0929264.1"
                     /translation="MSQQGLEALLRPKSIAVIGASMKPHRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVMAWPDIASLPFTPDLAILCTNASRNLALLDALGAKGCKTCIILSA
                     PTSQHEELLASARHYKMRLLGPNSLGLLAPWQGLNASFSPVPIKQGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTSAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLHGDRLMIISNGAAPAALALDELWSRNGKLATLSEETCLQLRQTLPAHI
                     DIANPLDLCDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAHALIETIKR
                     HPRGKFVTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHNLLQRAIAEGATSLDTHEVQPILHAYGLHTLPTWIASDSAE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTASEVQQAANAIFDRVKMAWPQA
                     RIHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMN
                     LARYLVIQGIKQRKIRARSALRPLDIVGLSQLLVQVSNLIVDCPEIQRLDIHPLLASA
                     SEFTALDVTLDIAPFDGDNESRLAVRPYPHQLEEWVEMKNGDRCLFRPILPEDEPQLR
                     QFIAQVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRMDNAEEILGVTR
                     AISDPDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDHGLKRLNGITMPNNRGMVA
                     LARKLGFQVDIQLDEGIVGLTLNLAKCDES"
     gene            complement(6820..7500)
                     /gene="tapT"
                     /locus_tag="OPY25_003763"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             complement(6820..7500)
                     /gene="tapT"
                     /locus_tag="OPY25_003763"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HCS0929265.1"
                     /translation="MTNNAVLQLRAERLARATRPFLARGNRVRRCQRCLLPLKSCLCD
                     TLTPSQAKSRFCLVMFDTEPMKPSNTGRLIADILPDTAAFQWSRTEPPQALLELVQHP
                     DYQPIVVFPASYAGEAREVISTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDHLPVIS
                     VDLSRLSAYRLREIHAEGQYCTAEVAIALLDLAGDPEAATSLGEHFIRFKTRYLAGKT
                     QHPGNVTA"
     gene            complement(7573..7992)
                     /gene="trxC"
                     /locus_tag="OPY25_003764"
     CDS             complement(7573..7992)
                     /gene="trxC"
                     /locus_tag="OPY25_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HCS0929266.1"
                     /translation="MNTVCTHCQAINRIPGDRLQDAAKCGRCGHELFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAEERSGKVRFVKVNTEAERELSARF
                     GIRSIPMIMIFKHGQVVDMLNGAVPKAPFDSWLNEAL"
     gene            8196..9233
                     /locus_tag="OPY25_003765"
     CDS             8196..9233
                     /locus_tag="OPY25_003765"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HCS0929267.1"
                     /translation="MNDELKNKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPAKSRT
                     DGGRRPARDERNNQSRDRKHETSPWRTVSRAPGDETPEKVDHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPDAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELAKASGTEHHGGVCFLIKKRNGTTVKQWVKQAADQDCVLALEDVANPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGESIVDVLDDFRQAGYTVVTTS
                     SDRGQALFSTTLPEKMVLVLGREYDYLPEAAREPDDLCVKINGTGNVESLNVSVATGV
                     LLAEWWRQNKA"
     gene            complement(9349..10038)
                     /gene="ung"
                     /locus_tag="OPY25_003766"
     CDS             complement(9349..10038)
                     /gene="ung"
                     /locus_tag="OPY25_003766"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCS0929268.1"
                     /translation="MATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAPPPSLVNMYKELEASIPG
                     FVRPAHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDPQRHHILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTI
                     DWTPVLPAESE"
     gene            10357..10740
                     /gene="grcA"
                     /locus_tag="OPY25_003767"
     CDS             10357..10740
                     /gene="grcA"
                     /locus_tag="OPY25_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HCS0929269.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKSGFAEDEVV
                     AVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            complement(10802..11389)
                     /gene="eamB"
                     /locus_tag="OPY25_003768"
     CDS             complement(10802..11389)
                     /gene="eamB"
                     /locus_tag="OPY25_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HCS0929270.1"
                     /translation="MTPMLLSAFWTYTLITALTPGPNNILALSAATAHGFRQSIRVLA
                     GMSLGFLVVMLLCAGIAFSLAVIDPAIIHLLSWVGAAYILWLAWKIATSPAADEKVRP
                     KPVGFWVSFGLQFVNVKIILYGITALSTFVLPQTQALNWVIGVSILLALIGTFGNVCW
                     ALAGHLFQRAFRHYGRQLNIILALLLVYCAVRIFY"
BASE COUNT         2708 a         2930 c         3089 g         2674 t
ORIGIN      
        1 aaggctcagt cgaaagactg ggccttttgc tttatctgtg gtctgccggt gagcactctc
       61 ctgaggagga caaatccgcc gggagcggat ttgaacgttg cgcagtaacg gcccgtaggg
      121 tggcgggcag cacgcccgcc ataaactgcc aggcatcaga caagtgaaga agcccgttct
      181 gacggacggg cttctttgcg tgtgtggtaa ctgtaaaaat gtaggcctga taagcgcagc
      241 gccatcaggc aacctgcacc gccggatggc agcttcgcct tatccggcct acagcaatta
      301 tcccgcctac gaagctggtg ctcttgtaga accgataaga gcacaaccca cccaatcgtt
      361 aacgatgaac tatcctttac acgtgcttat ataagcagtg aggattttca ttggctatca
      421 aaccttttaa ctaccagcaa gacttttcca gcattgactt ccgccagcag cctgaattgt
      481 atcaggttgg acgaggagag cagggggggc tactggttga accctacaaa agcgaaattc
      541 ttcctttctg gcgctataaa gatgaagcat cggcgatgaa atccgcagaa cagatctacc
      601 agttgttcga agcttaccgg cagcaggatg atttcgttgg tatggacatg gcgcgtaaat
      661 ttattcagat gggatacacc cgcgccaggc gatacgctaa ctataaaggt ggtaaaaagt
      721 atgcagaaga cggcagcctg aatacacggg gtaatgatcc tattaaggcc gcggcggcaa
      781 cggttttcaa aggttggtgg gataaaatcc gtcaggacga agactatctg aaacggaaac
      841 gccagcatca ggcacggtgg ggataaaaat tagcagacaa ataattaaca ctttatttac
      901 tttttagtct cgcgtaatct gaatctccaa aataaaaggc cgattaagcc tggcaacaag
      961 gagaacagta tggcagaaat tattcagcgt atagataaaa acaacgctga ggctccggag
     1021 atgcggcgac acatatgggc tatcgtgggg gcctcttccg gaaacttagt ggaatggttt
     1081 gatttctacg tctactcttt ctgctcgctc tattttgcac atatcttctt tccttctagt
     1141 aataccacta ctcagctttt gcaaacggca ggcgtctttg ccgccggttt tttaatgcgg
     1201 tctatcggtg gttggctgtt tggacgcatt gccgatcgac gcgggcgcaa agcctcaatg
     1261 ttgatttcgg tgtgcatgat gtgcatgggg tcgctggtga ttgcctgctt acctggttac
     1321 gataccatcg gcacctgggc accggcgctg ctacttattg caaggttatt tcaggggctc
     1381 tcggtagggg gagagtatgg gaccagcgcg acatatatga gtgaagttgc gcttgaaggt
     1441 cgtaagggat ttttcgcgtc gtttcagtac gttacgctta tcggtggcca actactggca
     1501 ttgctggtcg ttgtgatttt gcagcaggtt ctggaggatg ctgagcttcg tgcctgggga
     1561 tggcgtattc cctttgcgct gggcgccgtg ctggcggttg tggcgttatg gctacgtcgc
     1621 cagctggatg aaacctcgaa gcatgagact cgcgcattaa aagaagccgg ttcgttgaaa
     1681 ggtttgtggc gtaatcgcaa agcctttttg atggtgcttg gtttcaccgc ggcaggctcg
     1741 ctgtgctttt ataccttcac cacctatatg cagaaatatc tggtaaatac agcaggtatg
     1801 catgccaatg tcgccagcgg cattatgacg gctgcgctgt gtgttttcat gttggtgcag
     1861 ccgttattcg gcgcgttatc cgataagatt ggcaggcgca cctctatgct atgttttggc
     1921 gcactcgcga cgcttttcac cgttccaatt ctctccgcgt tgcagaatgt gacgtcgcct
     1981 tatgccgcat ttgctttagt gatgtgcgcg ctattgattg tgagtttcta tacctcgatt
     2041 agcgggatcc tgaaagcgga gatgtttccg gcgcaggttc gcgccctggg cgtcggttta
     2101 tcttacgcgg tagcaaacgc gttatttggc ggctctgcgg aatatgtcgc gctgtcgcta
     2161 aaatctgtcg gtatggagag ttcgttcttc tggtatgtta ccgcgatggc cgttctggct
     2221 ttcctggttt cgttgatgtt gcaccgtaaa ggaaagggct tacgccttta gtatcgcgcc
     2281 atttgccaga tagcgtaacc ggttgtcgcg ccagcgacat cccagacaaa atctttccag
     2341 ctccagccgc tgccttccgg gcggctgtcc cagagttctt ttgaggctcc gagactcaaa
     2401 gaaaacatca gccctatcgc tgcgctgcgg tcagggctta ctccctggtg acgcgcatac
     2461 tcattaccgg ctgccgatag catcgctgat gccataaaat gctgggcttt atcctgaccg
     2521 ctccagtggt cgttagccag atggctgcac ccggagagaa acaacaccgt aaaaggaatc
     2581 aacacgcgca ccagttcact cctaagagaa aaccccgtac aggacggggc ttcgattaca
     2641 ggatacggct aattaatctg tcgatgcgga tccggcgcag acggcgaatc aatttacgca
     2701 cttttatcgg atagtcggca atgctctgca ggtcacgata atgttttacg atggttgtgt
     2761 gcgttcggat aagttccagc tctttttccc gctgaggggc aagctcttgc ttaggatcgt
     2821 ggatcagaat ggcgttttcc agatccagac gccaggcgcg aggattcaga ttgttgccgg
     2881 tgagtagcat ccatttatca tctacccaca tccctttcaa atgataggta ttgtcgtcat
     2941 ctttccacag acgcaccaca agctgatcgg tattgacgta atactgtaaa cggctcagga
     3001 agcggcgcag gttaatctca tagagatagg gcagcgcgcc aatgatcttg aacggttcat
     3061 cttccggaat gtaaaaatca ttcgcggttt tatcgccaac aatgatttcg actttctttc
     3121 cgtcgcgcag tagctgaata atattccgca ccagtaccgc tggtagattg aagtaagggg
     3181 tacaaatggt gagcttatgc tccgcacagg gcatgagatg gaaaatggtt ttgttcagca
     3241 gactggattt tccaagcccg accagcggcg taacggagag ctgctcgtca ttagcgtcac
     3301 cctgaaaatg atatgacgca tcacgcagct cctgacggta taagcggata tcgtttttaa
     3361 tctccgggct tttcggccgc tgggtattat ccagacgatt cacaccacgg ccattcatca
     3421 gattttgcgt cacccagtca aacatgatgt ctgccatttg ccgattgcga atcagctggt
     3481 agcgatcgta gcgatatttg tcatgctgat ggagatagac atcgttcagg ctggcgccgc
     3541 tgtacaggac gctatcatca atgataaagc ctttaaaatg cagtacgcca agcgcttctc
     3601 gcgtattaat cggcacgccg taaaccggga catcaatgcc ggggttttcc tgcgccagtc
     3661 ggcaatacca gtctgcattg gtattcgagg ccgctgcgcc aatgcgcccg cgttgcgcgc
     3721 gatgccagtc gaccagcacc ctcacgtcca gttcaggacg ctgccgttta gccgcataga
     3781 gcgcgtcgag tataccttta cccccatcgt cctgttccag atacagggca acgatacaaa
     3841 tacgctgcgt cgcgctggcg attttctcca gcagtgtctc ccgaaaagta gcaggagtat
     3901 aaaagaaatc tacatcatca actgactgag aaatcttagg gagttgggca aggtgttgtt
     3961 gatgtttatt acgcttaaat tttgacaaca tcacagtgca tttcttctct gttcattgaa
     4021 gggtcctctg tgctatgcag acgacataag cgagcaataa taacatcagt acccgttaaa
     4081 gtggtcaaca tttccagtac attactcacg attcatcaca tttggccaga ttcagcgtca
     4141 atcccacgat gccctcgtcg agctgaatat cgacctgaaa tcccagtttt ctggccagcg
     4201 cgaccatgcc gcgattgttc ggcatcgtaa taccgttcag ccgcttcaat ccgtgatcgc
     4261 gagtataggc aatcaatttc tccattaaac ggcgtcctaa acccaaccct ttaagatctg
     4321 aacgcaccaa tacggcaaat tcggcatcta cgttgtcagg atcggagatc gcgcgcgtta
     4381 cgccgaggat ctcttcagcg ttgtccatcc gcctcacggc cacaaaggcc atttctcgat
     4441 cgtagtcgat ctgcgtcatg ttggctaaat cttcatgggt gaattcgttg atctcgctga
     4501 aataacggta gtaaagatcc tctttggtga cctgtgcgat gaattgtcgc agttggggct
     4561 catcttccgg caggatcgga cggaacaggc agcgatcgcc gtttttcatc tccacccact
     4621 cttcaagctg gtggggatag gggcgtaccg caagacgact ttcgttatcg ccatcaaacg
     4681 gggcaatatc cagcgtcaca tccagcgcgg taaactcact ggcggaagcc agcagcggat
     4741 ggatatccag acgctgaatt tccgggcaat cgacaatcag gtttgaaacc tggaccagca
     4801 attggcttaa accgacaata tccagcggac gcagcgcgct acgggcgcga attttccgct
     4861 gtttaatgcc ctgaatcacc agatagcgcg ccagattcat gttgagcggc ggcagcgcga
     4921 cgacggcctg ctcttccgga cgccactcta cgccgccttc acccaacata atcaaaggac
     4981 caaacaccgg atcgtgctcg accaccacac gcagctcctg cgcgccggcg cggttagcca
     5041 tgctttgtac cagcaaaccg tgaatccgcg cctgcggcca ggccatcttt acacgatcga
     5101 aaatggcgtt cgcggcctgt tgtacctcgc ttgcggtgcg caggtaaagc atgaccccct
     5161 gaacttcaga tttatgcgga atgtcgggcg agcgcagctt gagagctacc ggatagccta
     5221 tctgttcggc gatatgcact gcttcagcgc tgtcgctggc aatccaggtt gggagcgtgt
     5281 gcagcccata ggcgtgtaaa atcggctgta cttcatgggt atccagtgaa gtggcgcctt
     5341 ccgcaatcgc ccgctgtaac agattatgcg cctcagcggt attggacgtc aggttactcg
     5401 gcaacgctgg cgtttcccgc agttgcttct ggttacgccg gtattccacc atgtgcataa
     5461 acgcggtaat cgtgccttcc ggcgtgcggt aggttggtaa tccggcttcg ctgaacagcc
     5521 gtcttgcttc ctgagatgag aactcgccgc accagtttgt cagcagcgta acaaacttgc
     5581 ctctggggtg gcgcttaatc gtctcgatca gagcatgggc gctttccgta cccggcgcgg
     5641 cagcgctggg agagtggata accataagcg cgtcaaaatc ctgactggcg agcaggatat
     5701 ccagcgtttt gacgtaatgt tcgctgctgg cgtcatcaca cagatccagc ggattggcaa
     5761 tatcaatgtg cgcgggaagc gtctgccgta gttgcaggca ggtctcttcg ctcaatgtcg
     5821 ccagcttgcc gttacgcgac cacaactcat ctaacgccag cgcggcaggc gcggcgccat
     5881 tgctgatgat catcagtctg tcgccgtgta gcggacgcat atggctaagt gtttcgacgg
     5941 cggaaaaaag ctcgtgcgta tcctggactc gcagcaggcc tgcgcgctgg atggccgcat
     6001 cccacgcagg gtccattccc gcgctggtat taagtaaacg ctgggctgcc gggcttcggc
     6061 cgcttttaat caccagaatc ggtttgttac gtgaagcgct acgggcggcg gaaacaaaac
     6121 ggcgggcgtc gcttaactgt tccagataga gcaaaattgc gctggtcttg ctatcgcgcg
     6181 ccagatagtc cagtagttca tcgacatcaa tatccaggct atcgcccagc gcgataaagt
     6241 aggaaaagcc catttcacgc tgttgcgccc agtcaagaat agtattggac acggcggcag
     6301 actgggaaat aaaagcgagc ttgccctgtt taatcgggac gggagaaaag ctggcattca
     6361 gcccttgcca cggcgcgagg agcccaagac tgtttggacc cagcagacgc attttataat
     6421 gccgggcact ggcaagaagt tcttcatgtt gcgacgtggg agcagaaagg ataatgcacg
     6481 ttttacaacc tttcgcgcca agcgcgtcca gtaacgccag gttacggctg gcgttagtgc
     6541 ataaaatagc cagatcgggg gtgaaaggaa gactggcgat atccggccag gccatgacgc
     6601 ctaaaacggc tttccaggcg ggcgtcacgg gaaggacggg gccattgaat ccgcccgcca
     6661 acaagttacg catcatcagg taacccgcgc ggtggggctt cattgatgcg ccaatcaccg
     6721 cgatcgattt tggtcgcagt agcgcttcca gtccttgctg gctcataccg gtttccctta
     6781 cacagaagtg accggataat tttaaacgct ttcgctattt tatgctgtga cgtttcccgg
     6841 atgttgcgtt tttcctgcca gatagcgcgt tttgaaacgg atgaaatgtt cacctaaact
     6901 ggttgccgcc tcgggatctc ccgccagatc taacaacgct atcgcgactt cggcggtaca
     6961 atattgccct tcggcatgga tttcacgcag acgataagct gaaagacgcg ataaatcgac
     7021 ggaaatgacc ggcagatgat ccagataagg gcttttacga aacattttac gtgcttcggg
     7081 ccaggtgccg tccagcataa taaacagcgg cggtttcccg gcgggcgggg tggaaatgac
     7141 ctcgcgcgct tcgccggcgt aggacgcagg aaagaccact atcggctgat aatccggatg
     7201 ctgtaccagc tccagcaacg cctgcggcgg ctcggtacgc gaccactgaa acgccgcggt
     7261 atctggcaaa atatcggcta tcagccggcc ggtattgctg ggtttcatcg gttcagtgtc
     7321 aaacatgacc agacaaaaac ggcttttcgc ctgagaaggc gttaacgtat cacacaggca
     7381 agattttagc ggcagcaggc agcgttgaca gcggcgaacc cgattgcctc tggcaagaaa
     7441 agggcgagta gcgcgcgcaa gccgttcggc gcgtaactga aggacagcgt tattggtcat
     7501 agaaagcgtt tgcggagaaa aacgctattg tggcagaggt gaaaacgggg cacaagatgc
     7561 gccccgtggc gtttacagcg cttcgttcag ccagctgtcg aaaggcgctt taggcactgc
     7621 gccattaagc atatcgacca cctgtccatg tttaaaaatc ataatcatcg ggatgctgcg
     7681 gataccgaaa cgagcgctga gttcccgttc cgcctcggta tttactttga cgaaacggac
     7741 tttaccgctg cgctcttctg cgacatcctc gaagattggc gcaaagttac ggcaagggcc
     7801 gcaccagggt gcccaaaagt cgatcaccac tggaagatcg tccttcaaca gtttgtccag
     7861 cgtttcgccg gtcgcattaa tgacttctcc gtcaaacaac tcatgaccgc agcgtccaca
     7921 ttttgccgcg tcctgaagcc gatcgccggg gatgcggtta atggcctgac aatgggtaca
     7981 aacggtgttc atagctaacc tctgaatacg tcggaagacg tcccgctacg cgcgggatgt
     8041 ttctataatg ttatatatta tcgaggagtc tgtgctaaac aacaatgtgt tttattcaat
     8101 gagtacaata gtcgcaagct tttaaacgaa atcatggcta accggatgca catcgggtaa
     8161 tcttcgcgct tcgcgcagcg ctggtggaga aaagcatgaa cgatgaatta aaaaacaaaa
     8221 gcggcaaagt caaagtgatg tatgtccgta gtgatgatga ctctgataaa cgcacccata
     8281 acccgcgtac cgggaaaggg ggaggccgcc cagcaaagtc tcgcactgac ggtggacgtc
     8341 gccccgcccg tgatgagcga aataatcaga gccgtgaccg taaacatgaa acttcgccgt
     8401 ggcgcaccgt gtcccgcgcg ccaggcgatg aaacgcctga gaaagtcgat catggtggta
     8461 ttagcggtaa aagttttatc gaccctgaag ttttgcgtcg ccagcgtgcg gaagagacgc
     8521 gcgtctacgg cgaaaatgcc tgccaggcgc tattccagag ccgtcctgac gccatcgtgc
     8581 gcgcatggtt tatccaaagc gtaacgccgc gttttaaaga ggcgctgcgc tggatggcgg
     8641 cgaatcgtaa agcctaccat gtggtggatg aagccgaact ggcaaaagct tccgggactg
     8701 agcaccacgg cggcgtgtgt ttcctgatta aaaagcgtaa cggtacgacc gttaagcaat
     8761 gggtaaagca ggcggcggat caagactgcg tgctggcgtt ggaagatgtc gctaacccgc
     8821 ataatctggg cggcatgatg cgtagctgcg cgcacttcgg cgtgaagggc gtggtggtac
     8881 aggatgcagc gttgctggag tccggcgcgg cgattcgtac cgcggaaggc ggggcggaac
     8941 atgtccagcc aatcactggt gaaagcattg ttgacgtact ggatgacttt cgtcaggcgg
     9001 ggtacaccgt ggtgacgacg tccagcgatc gcggtcaggc gctctttagt acgaccctgc
     9061 cggaaaagat ggtgctggtc ttaggccgtg aatatgacta cctgccggaa gcggcgcgcg
     9121 aacccgacga tctgtgcgtg aaaattaacg gcaccgggaa cgtggaaagc ctgaatgtgt
     9181 cggttgcgac aggcgtactg ctcgccgagt ggtggcgaca gaataaagcg taagggctgc
     9241 agcccggtga cgcaacgcgc gccgggccaa tgatgtactt tctaccgccc ggtcagacaa
     9301 ggcgctttcg cgccgttatc cgggcgataa aacggcgagt cgccaacgtt attcactctc
     9361 agccggtaat actggcgtcc agtcgatagt tttctcgccg tgttgttcca gccattggtt
     9421 cgttagcgca aaatggttac agccaaaaaa tccgcggtgc gcagagagtg gcgagggatg
     9481 cggagctttc agaatatggt ggcgctgtgg atcaataatc gcgcctttct tctgggcgtg
     9541 cgagccccac agcaggaaga cgaccccttc gcggtgttgg ttaatcaggc ttatcacttt
     9601 atccgtaaag gtttcccacc ccaggctggc atgagagtgc gcctggcctg cccgtaccgt
     9661 gagcaccgta ttcagtaaca gtacgccctg gcgcgcccag ctttccagat aaccgtgcgc
     9721 ggggcgaaca aagccgggaa tggaggcttc cagctctttg tacatattca ctaatgacgg
     9781 cgggggagcg atcccaggac gcacggaaaa cgccagacca tgtgcctggc cggggccgtg
     9841 gtaaggatct tgtcccagga tcaccacctt aacgtcgccc agttccgtga agcgaaaggc
     9901 gttaaataca tctttttgcg gcgggtagac cgtgataccc gactgacgct cgccagcaac
     9961 agtgtgaagc gtattgataa agtaaggttg ctgtttctca tcagccagca catcgtgcca
    10021 ggttaactca gtcgccatct cgctctcctg cgaatttcca gttcccttag cttaactgct
    10081 tctttctgca gtgcaaaatc ctgcgtgcta caaaaacggt tacctacaaa agatagttga
    10141 aaatttatgt aaaaagttta taggtctgaa tggtgtaagt tgatgtaaaa caataaattc
    10201 ccttcatcac cctttttatg gtgtggtttt tattgattta aatcaaagaa tgaagggtga
    10261 tcgaagggta tatatacact caagcaacaa tggttttacc aattggccgg gattaggccg
    10321 accgaaatca aataattttg cctggggagg catcacatga ttacaggtat ccagattact
    10381 aaagccgcta acgacgacct gctgaattcc ttctggctgc tggacagcga aaaaggcgaa
    10441 gcgcgctgca tcgttgcaaa atccggcttt gctgaagatg aagttgtggc tgtcagcaaa
    10501 ctgggcgaga ttgaataccg tgaaattccg atggaagtta aaccggaagt acgcgttgaa
    10561 ggcggtcagc atctgaacgt taacgttctg cgtcgtgaaa ctctggaaga cgcggttaag
    10621 catccggaaa aatacccgca gctgactatt cgtgtttctg gttatgcggt gcgttttaac
    10681 tccctgacgc cggaacagca gcgcgacgtt atcgctcgta cctttaccga aagcctgtaa
    10741 ggcttatccg gtaataacaa gcggaagagg ccgggccttt tccgcttttg ttttatttgt
    10801 gtcagtaaaa aatccgcacc gcgcagtaca ccagcagtaa cgccagaatg atatttaact
    10861 ggcgaccata atggcgaaac gcccgctgaa acagatgtcc cgccagcgcc cagcacacat
    10921 taccgaacgt gccgatcaat gccagcaata tactgacgcc gatgacccag ttcagcgcct
    10981 gcgtttgcgg taaaacaaat gtagacagag cggtaatgcc gtacagaata attttgacgt
    11041 tcacaaactg caggccaaag cttacccaaa agccaaccgg ttttggtctg accttctcat
    11101 ccgccgctgg actggtggca attttccacg ccagccacag gatatacgca gcccctaccc
    11161 aactgagcaa atgaatgatt gccggatcga taaccgcaag ggaaaacgcg atcccggcgc
    11221 acagcagcat gacgaccaaa aatcccagac tcatacctgc cagtacacga atactctgcc
    11281 gaaaaccatg tgcagttgct gcgctaagcg cgagaatatt gtttgggccg ggggtaaggg
    11341 cggtgattaa tgtataagtc cagaaagcgc ttaaaagcat cggtgtcact tgtcatctcc
    11401 t
//
LOCUS       DAJVKX010000140        11196 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.140, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000140 DAJVKX010000000
VERSION     DAJVKX010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11196
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.140"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            891..2819
                     /gene="thrS"
                     /locus_tag="OPY25_003769"
     CDS             891..2819
                     /gene="thrS"
                     /locus_tag="OPY25_003769"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCS0929271.1"
                     /translation="MPVITLPDGSQRHYDHPVSPMDVALDIGPGLAKATIAGRVNGEL
                     VDASDLIENDATLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVVDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFVKRGESYKVSIL
                     DENIAHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPDKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQSEYVNELTQKLQNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVNDV
                     IEKLQQEIRSRSLQQLEE"
     gene            2823..3365
                     /gene="infC"
                     /locus_tag="OPY25_003770"
     CDS             2823..3365
                     /gene="infC"
                     /locus_tag="OPY25_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCS0929272.1"
                     /translation="MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKNDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            3461..3658
                     /gene="rpmI"
                     /locus_tag="OPY25_003771"
     CDS             3461..3658
                     /gene="rpmI"
                     /locus_tag="OPY25_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCS0929273.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            3709..4065
                     /gene="rplT"
                     /locus_tag="OPY25_003772"
     CDS             3709..4065
                     /gene="rplT"
                     /locus_tag="OPY25_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCS0929274.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     misc_feature    4181..4304
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            4186..4230
                     /gene="pheM"
                     /locus_tag="OPY25_003773"
     CDS             4186..4230
                     /gene="pheM"
                     /locus_tag="OPY25_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HCS0929275.1"
                     /translation="MNAAIFRFFFYFST"
     gene            4367..5350
                     /gene="pheS"
                     /locus_tag="OPY25_003774"
     CDS             4367..5350
                     /gene="pheS"
                     /locus_tag="OPY25_003774"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCS0929276.1"
                     /translation="MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     gene            5366..7753
                     /gene="pheT"
                     /locus_tag="OPY25_003775"
     CDS             5366..7753
                     /gene="pheT"
                     /locus_tag="OPY25_003775"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCS0929277.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFNG
                     VVVGEVVECAQHPNADKLRVTKVNVGGERLLDIVCGAPNCRQGLKVAVATIGAILPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAPVTATISDTLLITVEAVDACPRYLG
                     RVVKGINVNAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGI
                     VVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGGEHSGVNGETQNVLLE
                     CAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKTIERATRLLLDICGGDAGPII
                     DVSNEATLPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPT
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPIQAGLIMGTHREADLSLKRVKTMLNDKGYQ
                     EVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYNQNRQQNR
                     VRIFETGLRFVPDTQANLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAV
                     LDLTGKLGDIQFKAEMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRIVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            7758..8057
                     /gene="ihfA"
                     /locus_tag="OPY25_003776"
     CDS             7758..8057
                     /gene="ihfA"
                     /locus_tag="OPY25_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HCS0929278.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKEE"
     gene            8260..9240
                     /gene="btuC"
                     /locus_tag="OPY25_003777"
     CDS             8260..9240
                     /gene="btuC"
                     /locus_tag="OPY25_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HCS0929279.1"
                     /translation="MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWL
                     SARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGE
                     TSARQLGLPLWLWRNLLVIATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR"
     gene            9332..9883
                     /locus_tag="OPY25_003778"
     CDS             9332..9883
                     /locus_tag="OPY25_003778"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCS0929280.1"
                     /translation="MQNSLLNTHVTTIDGEVTTLEKYAGKVLLIVNVASRCGLTPQYE
                     QLENIQKAWADQGFVVLGFPCNQFMGQEPGSEEEIKTYCASTWGVTFPMFSKIDVNGD
                     ARHPLYQKLIAAAPTAVAPEKSGFYERMVSKGRTPLYPDDILWNFEKFLVGRDGQVVQ
                     RFSPDMTPEDPIVMESIKIALAK"
     gene            9883..10632
                     /gene="btuD"
                     /locus_tag="OPY25_003779"
     CDS             9883..10632
                     /gene="btuD"
                     /locus_tag="OPY25_003779"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HCS0929281.1"
                     /translation="MSQLMQLKDVAESTRLGPLSGEVSAGEILHLVGPNGAGKSTLLA
                     RMAGLTSGEGSIRFGGAPLEAWATATLAQHRAYLAQQQNPPFAMPVWHYLTLHQPDKT
                     RTGQLNEVADMLGLGDKLGRSVNQLSGGEWQRVRLAAVVLQIHPDANPVGQLLLLDEP
                     MNSLDVAQQNALDRVLHHLCQAGIAIVMSSHDLNHTLRHAHKAWLLKRGKLIACGRRE
                     EVLTPSYLAQAYGLRFRRLDVEGHPMLISAT"
     gene            10709..11173
                     /locus_tag="OPY25_003780"
     CDS             10709..11173
                     /locus_tag="OPY25_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0929282.1"
                     /translation="MRFWLLVITALFLAGCSTHRAPAPNARLSDSITVIAGLNDQLQS
                     WRGTPYRYGSMSRRGVDCSGFVVVTMRDKFDLQLPRDTREQSKIGTRIDKDELLPGDL
                     VFFKTGSGESGLHVGIYDTNNEFIHASTSRGVMRSSLDNVYWRKNFWQARRI"
BASE COUNT         2779 a         2633 c         3056 g         2728 t
ORIGIN      
        1 tagagccttt agaaaaaatg cttagtatta aaaatattac catcaggcaa ataaggtgtg
       61 gtacggaaaa tcttctggca agatattctg aatctggtag tctataatca ttactcatca
      121 ctatcttccc gatatcaaaa ccgtgttatt gaaatattaa cactcattaa cactcctatc
      181 tactgcgcct ccgatagcat gaagctatca agcgtttgca gcacaaacat caaacaatgt
      241 aaatgctttt gataattacg catgattgtt actgtgttta tatacagtgg cattcgaaga
      301 ttcatcatga ggttcccgag tcctgtaaaa gactatacag agaaagagct atcactcgac
      361 gagtaattca tctcacatcg tgccgcgaca tacttcaagc aacacagacg aattacaagt
      421 acggcatcat aagtgagacg ttgctagtta tagaagcttc atagcagcat gtaatggctc
      481 tttgctggta tgtgctttgg aaagtgggtt tcgtattgtg cgttatcgca tgctgccagg
      541 tccccatctg gagaatatag atagcggtcg tcgtgaaaag ctatctgatg tgaatgcctc
      601 atacggtggc agtaagccga gattcagagt gaccatgtac atcattaacg atacgcgtgc
      661 cgggtagtgt gttgggattc aggttctgta gaacagaaag atgcaatctc ccttttttta
      721 gtgttaccat catcatgccg gacgaaaata gcgattttcg tctgtgtcga aggttgtgcg
      781 ccaatttagc aatggttggc tagatggata cacaactcac tgtcaataaa ttcattttct
      841 ctttgtatgt gatcttgcgt atgggtcacc actgcaaata aggatattac atgcctgtta
      901 ttactcttcc tgatggcagc caacgccatt atgaccaccc tgtaagcccg atggatgttg
      961 ctctggacat tggtcctggc ctggcgaaag ccaccattgc gggccgtgtg aatggcgagc
     1021 tggttgatgc ttccgatctg attgaaaatg atgcgacgct ttccatcatc accgcaaaag
     1081 atgaagaggg tctggagatc attcgtcact cttgcgcgca tctgttaggt cacgctatca
     1141 agcaactttg gccgcacacg aaaatggcga tcggtccggt tgtcgacaac ggtttttact
     1201 atgacgttga tcttgaccgc acgctaactc aggaagatgt cgaagcgctc gaaaagcgga
     1261 tgcatgagct cgccgagaaa aattacgacg ttatcaagaa gaaagtcagc tggcacgaag
     1321 cgcgtgaaac cttcgtgaag cgtggtgaaa gctacaaagt ttccattctt gatgaaaaca
     1381 ttgctcatga tgacaagcca ggcttgtacc atcatgaaga atatgtcgac atgtgtcgtg
     1441 gtccgcacgt gccgaatatg cgtttctgcc atcactttaa actgatgaaa actgccggcg
     1501 catactggcg cggtgacagc aataataaga tgttgcagcg tatttacggt acggcatggg
     1561 cagataaaaa agccctgaac gcttatctgc agcgcctgga agaggccgca aaacgcgacc
     1621 accgtaaaat tggtaagcag ctcgacctgt atcatatgca ggaagaagcg ccgggcatgg
     1681 tgttctggca taacgacggc tggactatct tccgcgagct ggaggtcttt gttcgttcta
     1741 aactcaaaga gtaccagtat caagaagtta aaggcccgtt catgatggac cgtgtgctgt
     1801 gggaaaaaac cgggcactgg gacaactata aagatgcgat gttcaccaca tcttcagaaa
     1861 accgcgaata ttgcatcaag ccgatgaact gcccgggcca cgttcagatc tttaaccagg
     1921 gtctgaaatc ctatcgtgat ttgccgctgc gtatggcgga attcggtagc tgccaccgta
     1981 acgagccatc aggcgcgctg catggtctga tgcgcgtacg cggctttacg caggatgatg
     2041 cgcatatctt ctgcaccgaa gagcagatcc gcgatgaagt taacgcttgt attcgtatgg
     2101 tctacgatat gtacagcacc tttggcttcg agaagatcgt cgtcaaactt tccactcgtc
     2161 ctgataagcg tatcggcagc gatgagatgt gggatcgtgc tgaggcggat ctggcggttg
     2221 cgctggaaga aaataatatc ccgtttgagt atcaactggg tgaaggcgca ttctacggtc
     2281 cgaaaattga atttacctta tatgactgcc tcgatcgtgc atggcagtgc ggtacagtac
     2341 agctggactt ctccttaccg tctcgtctga gcgcctccta tgtaggcgaa gacaacgagc
     2401 gcaaggtgcc ggtaatgatt caccgtgcga ttcttgggtc gatggaacgc ttcatcggta
     2461 tcctgaccga agagttcgct ggtttcttcc cgacatggct cgcgcctgtt caggtagtcg
     2521 tgatgaatat taccgattcg cagtctgaat acgttaacga attgacgcag aaactacaaa
     2581 atgcgggcat tcgtgtaaaa gcagacttga gaaatgagaa gattggcttt aaaatccgcg
     2641 agcacacttt acgtcgtgtc ccttatatgt tggtctgtgg tgataaagag gtggaagcag
     2701 gcaaagttgc cgttcgcacc cgccgcggta aagacctggg cagtctggac gtaaatgacg
     2761 tgattgagaa gctgcaacaa gagattcgca gccgcagtct tcaacaactg gaggaataaa
     2821 gtattaaagg cggaaaacga gttcaaacgg cgcgtccgaa tcgtattaat agcgaaattc
     2881 gcgcgcaaga agttcgctta acaggtctgg aaggcgagca gcttggtatt gtgagtctga
     2941 gagaagctct ggaaaaagct gaagaagccg gagtagactt agtcgaaatc agccctaacg
     3001 ccgagccgcc ggtttgtcgt ataatggatt acggcaaatt cctctatgaa aagagtaagt
     3061 cttctaagga acagaagaaa aagcaaaaag ttatccaggt gaaggaaatt aaattccgtc
     3121 ctgggacaga tgaaggcgac tatcaggtaa aactccgcag cctgattcgc tttctcgaag
     3181 agggcgataa ggccaagatc acgctgcgtt tccgcggtcg tgaaatggcc caccagcaaa
     3241 tcggtatgga agtgcttaat cgcgtgaaaa acgatttgca agaactggca gtggtcgaat
     3301 ccttcccaac gaagatcgaa ggccgtcaga tgatcatggt gcttgctcct aagaagaaac
     3361 agtaaggcct tcaagtaaca attctgtgaa gccttcgggc ttcacaggtt ttgttcgcct
     3421 atgtttcgtt tattaacaat gcgaagtgga agttattaaa atgccaaaaa ttaagaccgt
     3481 acgcggtgct gctaagcgct tcaaaaaaac cggtaaaggt ggttttaagc acaagcacgc
     3541 taacctgcgt cacattctga ccaaaaaagc gactaaacgt aaacgtcacc tgcgtccgaa
     3601 agccatggtt tctaaaggcg atctgggctt ggttatcgcg tgcctgccgt acgcataagc
     3661 cgttaacgtt tttaactttt taattagaat agatacagga gagcacatat ggctcgcgta
     3721 aaacgtggtg taattgcacg cgcacgtcac aagaaaattt tgaaacaagc caaaggctac
     3781 tacggtgcgc gttctcgcgt ataccgcgtt gccttccagg cagttatcaa agctggtcag
     3841 tatgcttacc gtgaccgtcg tcaacgtaag cgtcagttcc gtcaactgtg gattgcgcgt
     3901 atcaacgcag cagcacgtca gaacggtatt tcttacagca aattcatcaa cggcctgaaa
     3961 aaagcctctg ttgaaatcga ccgtaagatc ctggctgata tcgccgtatt cgacaaagtc
     4021 gcgttcaccg cgctggttga aaaagcgaaa gcagctctgg cataagccag tgaaaagagg
     4081 gagcctggct ccctctcttt tatttactgt tcagtgagtt gacaattgac ctgtaaccct
     4141 tttcaataaa ggatattcgg ttttaccaca taaggtaacg caagcatgaa cgctgctatt
     4201 ttccgtttct ttttttactt tagcacctga tcccaggagg ctagcgcgtg aaaaacgaaa
     4261 cgaaaaacag cgtaaaaaag cctcctgatg gaggcttttt ttgtatctga aatcgagaga
     4321 ttacgtccaa tgaaccggtg tcttcaccga cacaatgagg aaaaccatgt cacatctcgc
     4381 agagctggtt gccaatgcag cggccgccat taaccaggcg tcagatgttg ccgcgttaga
     4441 caatgtacgc gtcgaatatt tgggcaagaa agggcattta acccttcaga tgacgaccct
     4501 acgcgatctg ccgccggaag agcgtccggc agccggggca gtcattaacg ccgcgaaaga
     4561 gcaggtacaa caggcgctta acgcgcgtaa agccgagctg gaaagcgcag cgcttaacgc
     4621 tcgtctggcc gctgaaacta tcgatatctc cctgccggga cgccgtattg agaacggcgg
     4681 tctgcatccg gtcacgcgta ccattgaccg tattgaaagt ttcttcggcg agcttggttt
     4741 taccgtggcg actggcccgg aaatcgaaga tgactaccat aacttcgatg cgttaaacat
     4801 tccgggtcat cacccggccc gcgccgatca tgataccttc tggtttgacg cgacccgtct
     4861 gctgcggacc cagacgtctg gtgtccagat ccggacgatg aaagcgcagc aaccgccgat
     4921 ccgtattatt gcgccgggcc gtgtataccg taatgactac gaccagacgc atactccgat
     4981 gttccatcag atggaaggtc tgattgttga taccaacatc agcttcacca acctcaaagg
     5041 tacgctgcac gacttcctgc gtaatttctt tgaggaggat ctgcagattc gcttccgtcc
     5101 ttcttatttt ccgttcaccg aaccttctgc ggaagtggat gtgatgggta aaaacggcaa
     5161 atggctggaa gtgctgggct gcgggatggt gcatccgaat gtgctgcgta atgtcggtat
     5221 cgatccggaa atctattctg gcttcgcttt tggtatgggg atggaacgtc tgaccatgtt
     5281 gcgttacggc gtcaccgacc tgcgttcatt cttcgaaaac gatctgcgtt tccttaaaca
     5341 gtttaaataa aggcaggata aaacaatgaa attcagcgaa ctgtggttac gcgagtgggt
     5401 taacccggca attgatagcg atgcgttggc taaccagatt acgatggctg gcctggaagt
     5461 agacggcgtt gagccggtcg cgggaagctt caatggcgtt gtggttgggg aagtggttga
     5521 gtgcgcccag catccgaacg ctgacaaatt gcgtgtaacg aaagtcaacg tcggcggaga
     5581 acgcctgttg gatatcgtct gcggcgcgcc aaactgtcgt caggggctga aagtagcggt
     5641 ggccactatt ggcgctattc tgccgggcga tttcaaaatt aaagcggcga aactgcgcgg
     5701 cgaaccgtct gaagggatgc tgtgctcctt ctccgaactg gggatttccg acgatcacag
     5761 cggcattatc gaactgccgg cggatgcgcc gttgggtacc gacatccgtg aatacctgaa
     5821 gcttgacgac aataccatcg aaattagcgt cacgccgaac cgtgcggatt gcttaggtat
     5881 catcggcgtt gcgcgtgatg tggcggtact gaacaaagcg ccgctccagg agcctgaaat
     5941 ggcgccggtt acggcaacca tcagcgatac gctgctgatt acggtagagg ctgttgatgc
     6001 gtgtcctcgc tatcttggcc gggtggtaaa aggtatcaat gttaacgcgc cgacgccgct
     6061 gtggatgaaa gagaaactgc gtcgctgcgg tattcgctcc atcgatgcgg tggttgacgt
     6121 cacgaactat gtgctgctcg aactgggtca gccaatgcat gctttcgata aagatcgcat
     6181 tgatggcggt attgtcgtgc ggatggcaaa agagggtgaa accgtcgtcc tgctggacgg
     6241 tagcgaagcg acgttaaatg cggacacgct ggtgatcgcc gatcaccata aggcgctggg
     6301 gatagccggt atttttggcg gcgaacattc cggcgtgaac ggcgaaacgc aaaatgtgct
     6361 gctggagtgt gcgtacttta atccgctgtc tatcaccggt cgcgctcgcc gccacggtct
     6421 gcataccgat gcgtctcacc gctacgagcg cggggtggac ccggcgctgc aatataaaac
     6481 gatagagcgc gctactcgtc tgcttcttga tatctgtggc ggtgatgcgg gtccgataat
     6541 tgatgtgagc aacgaagcaa cgttgccgaa acgcgccacc attactctgc gtcgcagtaa
     6601 actggatcgc ctgatcgggc atcatattgc ggatgagcag gtcagtgata ttctgcgtcg
     6661 tctgggctgt gaagtgaccg aagggcagga cgagtggaaa gccgtggcgc cgacctggcg
     6721 tttcgatatg gagattgaag aagatctggt ggaagaggtg gcccgcgttt acggctataa
     6781 caatattccg gacgagccaa tccaggccgg tttaatcatg ggaacgcacc gtgaagccga
     6841 tctgtcgttg aagcgggtta aaaccatgct gaacgacaaa ggctatcagg aagtgattac
     6901 ctatagcttt gtcgatccta aagtacaaca gctcatccat ccaggcgcag aagcgctgct
     6961 gctgccaaac cctatctccg ttgagatgtc ggcgatgcgt ctgtctctgt ggagcggatt
     7021 gttggcgacg gtggtctata accaaaaccg tcagcagaat cgcgtgcgta tttttgaaac
     7081 cggtttacgt ttcgttccgg atacacaagc caatctgggt attcgacagg atctgatgct
     7141 ggctggcgtg atttgcggta accgctatga tgagcactgg aacctggcaa aagagaccgt
     7201 tgatttctat gatttgaaag gcgatctgga agcagtattg gatttaaccg gcaaactggg
     7261 tgatatccag tttaaggcgg agatgaatcc ggctctgcat ccgggacagt ctgcggcgat
     7321 ttatctgaaa gatgaacgta ttggttttat tggggttgtt caccctgaac tggaacgtaa
     7381 actggatctg aatggtcgta cgctggtgtt tgaactggaa tggaataagc tcgcagaccg
     7441 tatcgtgccg caggcgcggg agatttcacg cttcccggcc aaccgtcgcg atattgcggt
     7501 tgttgttgca gaaaacgttc ccgcagcgga tattttatcc gaatgtaaga aagttggcgt
     7561 aaatcaggta gttggcgtaa acttatttga cgtgtaccgc ggtaagggtg ttgcggaggg
     7621 ttataaaagc ctcgctatca gcctgatcct tcaggatacc aaccgtacac tcgaagaaga
     7681 ggagattgcc gctaccgtcg ccaaatgtgt agaggcatta aaagagcgat tccaggcatc
     7741 attgagggat tgaacctatg gcgcttacaa aagctgaaat gtcagaatat ctgtttgata
     7801 agcttgggct tagcaagcgg gatgccaaag aactggttga actgtttttc gaagagatcc
     7861 gtcgtgctct ggaaaacggt gagcaggtga aactctctgg ttttggtaac ttcgatctgc
     7921 gtgataaaaa tcaacgtccg gggcgtaacc cgaaaacggg tgaagatatt cctattacag
     7981 cacggcgcgt ggtgaccttc agacccgggc agaagttaaa gagccgggtc gaaaacgctt
     8041 cgcccaaaga agagtaatca gatccaggca taacatccat cagggtgtat tgcggcagat
     8101 acgctgccat cccgaaagta gatcagcggg atgacagcgt atttgtcagc ctgaaagatg
     8161 acccgtataa ctaaaaaggc cgcattgcgg ccttttttct ttcaagtaaa ggatacccac
     8221 cgtaaaatca cgctacctct tttcagctga atggataaca tgctgacttt tgcccgccaa
     8281 caacagcgac gaaacgttcg ctggcttctg agcctgtcac tgctggtgct actggctaca
     8341 cttctgagct tatgcgcagg cgaacagtgg attgcccccg gtgactggtt aagcgcccgg
     8401 ggggaactgt ttgtctggca aattcgcctt ccccgcacgc ttgcggtatt gctggttggc
     8461 gctgcgctgg cgctatctgg cgccgtgatg caggcgctgt ttgaaaaccc acttgctgaa
     8521 ccgggtctgc tcggcgtttc gaatggggcc ggtgttgggc ttattgccgc cgtcttactg
     8581 gggcaggggc aactgccagg atgggcgctg gggctgtgcg ctatagccgg cgcgctcatt
     8641 attacgttaa tcctgctgcg ttttgcgcgt cgccatctct ctaccagccg cttgttgttg
     8701 gcgggcgtcg cgctgggcat tatctgtagc gcgctgatga cgtgggctat ctatttttcc
     8761 acctctttcg atctgcggca attaatgtac tggatgatgg gaggatttgg cggcgttgac
     8821 tggcagcaga gctggctaat gattgcgctc atcccggtac tgatctggat atgttgccag
     8881 tcgcaaccgc tgaatatgct ggcgctaggg gaaacctcgg cgcggcagct tggcctgccg
     8941 ctgtggctct ggcgcaattt gttggtcatc gccaccggct ggatggtggg cgtcagcgtg
     9001 gcgatggcgg gggcgattgg ttttatcggt ctggttattc cgcacatcct gcgcttatgt
     9061 ggtttaaccg atcaccgggt tttacttccc ggctgcgcgc tggccggggc tatcgccctg
     9121 ctattggctg atgtggtcgc ccgactggcg ctggcgtcgg ctgaactgcc tatcggggtg
     9181 gtcaccgcca cattgggggc accagtgttt atctggctgc tactcaaatc cgcgcgttag
     9241 cgcatcggta aacaactgct ttcatcattc gcagtctatg attaaaggct aacgatgaaa
     9301 cccgctattc taccgacatc agggagacac catgcaaaac tcgcttctta atactcacgt
     9361 tacgacgatt gatggagagg tcactacact tgaaaaatac gccggaaaag tgctgctcat
     9421 tgtaaacgtc gcctccagat gtggcctgac gccgcaatat gaacagttgg aaaatatcca
     9481 gaaggcgtgg gcagatcagg ggtttgtcgt gttgggtttt ccctgcaacc agtttatggg
     9541 gcaggagcca ggcagcgaag aggagattaa aacctattgt gccagcacct ggggcgtcac
     9601 gttcccgatg ttcagtaaaa ttgatgtgaa tggcgacgcg cgccatccgc tgtatcaaaa
     9661 actgatagcc gctgcgccaa cggcagtcgc gccggagaag agcggctttt acgaacggat
     9721 ggtaagcaaa gggcgtacgc cactctatcc ggatgatatt ctgtggaatt ttgaaaaatt
     9781 tttggtaggc cgggatggtc aggtggtaca gcgtttttcg ccggatatga cgcctgaaga
     9841 tcctattgtg atggaaagca taaaaatcgc gttggcaaaa taatgtctca attgatgcaa
     9901 ttaaaggacg tcgccgagag cacccgcctg gggccgcttt ccggcgaagt aagcgcagga
     9961 gagatccttc atcttgtcgg gccgaacggc gccgggaaaa gcacgctact ggcgcgtatg
    10021 gcggggttaa cctccggcga ggggagcatc aggtttggcg gagcgccgct ggaggcatgg
    10081 gcgacggcaa cgcttgccca acaccgcgct tatcttgcgc aacagcaaaa tccgccgttc
    10141 gccatgccgg tctggcatta cctgacattg catcaacctg ataaaacgcg aaccgggcag
    10201 cttaacgagg tggccgatat gcttggattg ggcgacaaac tggggcgaag cgtgaatcag
    10261 ctttccggtg gcgagtggca gcgcgttcgc cttgctgccg ttgtactaca aattcatccc
    10321 gacgctaatc cggtcggtca attattgctg cttgatgagc cgatgaacag tctcgatgtt
    10381 gcgcaacaaa acgctctgga tcgggtatta catcatttat gtcaggcagg aattgcgatt
    10441 gtgatgagta gccacgatct gaaccacacg ctgcgccatg cgcataaagc ctggttacta
    10501 aagcgcggta aactcattgc ctgcggccgc cgggaagagg tgctcacccc ctcttatctg
    10561 gcgcaagcct acggtttgcg ctttcgacga ctcgacgtcg aggggcatcc aatgctcatt
    10621 tcggccactt aagtaaaatc gtttcttgaa aagcaggtaa tttcgacgct aaattaatac
    10681 caaaataaaa acagaggatt gttgcggcat gcgtttttgg cttcttgtta tcacagcatt
    10741 gttcctggca ggatgcagta ctcatcgggc accggcgcca aatgccagat tatcagactc
    10801 cattaccgtc attgcgggtc tgaacgatca gttgcagtcc tggcgcggta cgccataccg
    10861 ctacggcagc atgagtcgca gaggcgtgga ctgttccggc tttgtggtag tcactatgcg
    10921 cgacaagttt gatttgcagt tgcctcgtga tacgcgtgaa caatcaaaaa tcggcaccag
    10981 aatcgataaa gatgaattgc tgcccggaga tttggttttc tttaaaaccg gttcgggcga
    11041 aagtggttta catgttggta tttacgatac aaataatgag tttattcatg cctctaccag
    11101 tcgtggcgtg atgcgttcat cgctggataa tgtgtactgg cgaaaaaact tctggcaggc
    11161 acggcgaatt taacctcgca gacgatataa atttta
//
LOCUS       DAJVKX010000141        11093 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.141, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000141 DAJVKX010000000
VERSION     DAJVKX010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11093
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.141"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            605..2239
                     /locus_tag="OPY25_003781"
     CDS             605..2239
                     /locus_tag="OPY25_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCS0929283.1"
                     /translation="MLRREKQKQRIIWDKLMIKGKLALVTCALTLVFTSSLFAASDTA
                     DGRTLKLAIGPEPTEGFDPMLGWSHGSYLLLHAPLLKQNADMSWGDLLTEKVDTSPDG
                     KIWTLTLKPGLKFSDGSPLTAEDVVFTYNKAAKSGGKIDMGNFSHARALDARRIEMTL
                     SHPQSTFVNVLGSLGIVPASRYDEKTFAREPIGAGPYRLVSFQPGQQLIVEANPWYAG
                     KKNDFNRLVFVFLDEDNAYAAARSGQLGLVRIAPSMAVTPQQDNLKLWVRDSVENRGI
                     VFPMVPAGKKDANGYPVGNDVTADVAIRRAINYAINRKQLAEQVMEGHAIPAYSAVQG
                     LPWQNPSVVFSDGDIAKARAILEEAGWKINSAGVREKAGKEARLTLWYASGDSTRRDL
                     AEAVRAMLQRLGIVVSLQSGSWETVERHMHANPTLFGWGSLDPMELFHHYSGKAAGVE
                     YYNPGYYSNPAVEAHLKQAIDAPDWQKAIPFWQQVEWDGKQGAGVQGDAAWAWLLNIQ
                     HTYLANPCIDLGKGSPEIHGSWSVLNNLDDWTWTCR"
     gene            2239..3213
                     /locus_tag="OPY25_003782"
     CDS             2239..3213
                     /locus_tag="OPY25_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0929284.1"
                     /translation="MKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLH
                     VPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDMGYSMLFNMPVASVIRERFATSFA
                     LLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVR
                     WPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSE
                     FIRFARAQGDKGWSLLRHQVLRHAITPALCLQFASLGELMGGALLAEKVFAYPGLGQA
                     TIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLERPDAL"
     gene            3203..4015
                     /locus_tag="OPY25_003783"
     CDS             3203..4015
                     /locus_tag="OPY25_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0929285.1"
                     /translation="MLYNPAPTLFRLLLSVTCLLFIAGYGYATLSQPPEVNLLARHLS
                     PDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAALCSGVIALVMAAVARIHPRLDLL
                     VRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
                     YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEP
                     SLGLLLADALRFISHGNWWLVLFPGLMLFTLVMLFDQFARAIQRLWLRSDVC"
     gene            4009..4806
                     /locus_tag="OPY25_003784"
     CDS             4009..4806
                     /locus_tag="OPY25_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCS0929286.1"
                     /translation="MLSLQRVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGG
                     SGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNP
                     MLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLAPTVLERFPRQLSGGMAKRILACHA
                     SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVA
                     LHQGYITDNIRCERLQPEEMSEPLKRQWQALPELNPLFMPTGEGIEC"
     gene            4800..5390
                     /locus_tag="OPY25_003785"
     CDS             4800..5390
                     /locus_tag="OPY25_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCS0929287.1"
                     /translation="MLSCRDLVIRQGGKVLWQNLTFTISAGERVGIHAPSGTGKTTLG
                     RVLAGWQKPTTGDVLLDGSPLPLHQYCPVQLVPQHPELTFNPWRSAGDAVRDAWQPDP
                     ETLRRLYVQPEWLTRRPMQLSGGELARIAILRALDPRARFLIADEMTAQLDPSIQKAI
                     WVYVLEVCRSRSLGMLVINHQSALLDQVCTRHLQVE"
     gene            complement(5472..6605)
                     /locus_tag="OPY25_003786"
     CDS             complement(5472..6605)
                     /locus_tag="OPY25_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCS0929288.1"
                     /translation="MEYLARLNIVAMLMSTTFWINLAVVFFVTLITYWLINWLLNVVY
                     KALQRPDKKDDAHGRLRPIVFEMLKKTSKMLIFFAAFLFSLRFVALPDRLFSTLSHAW
                     FLVVAIQMAIWLDQGVQSWMRHLLYAPGSNKNPVTLVILGMILRVLVWSMMLLSILAN
                     VGVDITALVASLGVGGIAIALAVQTVLSDVFASLSIGFDKPFEIGDFVVFNDVAGTIE
                     HIGLKTTRIRSLSGEQIVCANAQLLQQTIHNYKRMQTRRIVFTFGVATATPPEKLRLI
                     GDMVKKIITDVGETQFDRAHLLAFGQDRLTYEVVHIVNTADYNKYMDIQQEINIRIIE
                     KLIENDIELALPSLVVRAPVQVEETRDYSNTADAKNADKRVMQ"
     gene            6799..7125
                     /locus_tag="OPY25_003787"
     CDS             6799..7125
                     /locus_tag="OPY25_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-helix bundle copper-binding protein"
                     /protein_id="HCS0929289.1"
                     /translation="MQQEHRECIEQCYECAAACDICASSCLREDNVEMMKHCIELDMQ
                     CAAICRLAAQFMALESEYSQKLCRLCADICKACAEECARHDHDHCQNCARACSQCADA
                     CLKMAA"
     gene            7134..7210
                     /locus_tag="OPY25_003788"
     tRNA            7134..7210
                     /locus_tag="OPY25_003788"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7168..7170,aa:Arg,seq:tct)
     gene            7322..7969
                     /gene="zinT"
                     /locus_tag="OPY25_003789"
     CDS             7322..7969
                     /gene="zinT"
                     /locus_tag="OPY25_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460229.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HCS0929290.1"
                     /translation="MIHLKKLTMLLGMLLVNSPAFAHGHHAHGAPMTEVEQKAAAGVF
                     DDANVRDRALTDWDGMWQSVYPYLVSGELDPVFRQKAKKDPEKTFEDIKAYYRKGYAT
                     NVETIGIENGVIEFHRDNNVASCKYNYAGYKILTYASGKKGVRYLFECKDANSKAPKY
                     VQFSDHIIAPRKSAHFHIFMGNTSQQALLQEMENWPTYYPYQLKANEVVDEMLHH"
     gene            8078..8866
                     /gene="aadA"
                     /locus_tag="OPY25_003790"
     CDS             8078..8866
                     /gene="aadA"
                     /locus_tag="OPY25_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cryptic aminoglycoside nucleotidyltransferase
                     ANT(3'')/ANT(9)"
                     /protein_id="HCS0929291.1"
                     /translation="MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGDLKP
                     NSDIDLLVTICQPLTETQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFP
                     PSREMQFGEWLREDIYQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAA
                     QLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPE
                     EYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKAYIPTQFT"
     gene            9011..9604
                     /locus_tag="OPY25_003791"
     CDS             9011..9604
                     /locus_tag="OPY25_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929292.1"
                     /translation="MTGSASSVLKTDTRLLSENLFLNYGLESLFKDVAIIAGNVNYIV
                     FDIDDYYTVQQYITSTFKTVLIGIVTHNEYNFIDEHHAIYRIKVDASIAEWRELLILA
                     AAGQFFPRSEKVRLTANERNVLAMLVKGMDIRQISCELNVHLKTIYSVRYHVLTKLGC
                     RTVLDYQILSVSKAFTHWLTINNVDNVIFRVNSKVIA"
     gene            9673..10521
                     /locus_tag="OPY25_003792"
     CDS             9673..10521
                     /locus_tag="OPY25_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCS0929293.1"
                     /translation="MATFSISAMAAQCGVTTANIRSWERYGLLQPTKDEAGNRFYCIE
                     DAIRIQHIIDALSKGFSLKEIKPALYGEETHCRSGWLFYQEEILAQCRKFEPAKLRKL
                     LWRYGREIPPCIVIESILRPLWLWLSAGDDDARRFEKALLDTAIIEYATFQLSSVRKA
                     PAGTMLIAAFSLNDPIELWLETIKYCSEGMRVEVIPWQAPMPDLLSTSFEHIVLWHDE
                     TLTPAQENLIQALKESGKFSLHVKNGSGLTLLPAVYRQHEMPESMQHVAPQIHANGYE
                     KSGTAR"
     gene            complement(10776..11024)
                     /locus_tag="OPY25_003793"
     CDS             complement(10776..11024)
                     /locus_tag="OPY25_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCS0929294.1"
                     /translation="MTTITLVNEQNSTGNPFSAHMLCEQRAIQEITYELLQSQQHVSN
                     KDIIAKLIEKLETEKDVVQLDIYRNALEAVFFQTPDDI"
BASE COUNT         2637 a         2615 c         2951 g         2890 t
ORIGIN      
        1 tgcaccctcc tgttgatgtc gtacctgatg gacaaatatc cgttgaagcc ggatatattc
       61 cccatgccgt gtttttataa cttgcgcatc ctgtcagcaa tgagaacagt acggctaaaa
      121 aaatcatcac gagccctggc ggcgttaaca tttttcggtt ggactccata gcatgtcatt
      181 tcatcgggtt gccatatgac tggcgttctg ctggtaagtt tcattaacgc ctggttcgtt
      241 taatattggt ttaggtttaa agccaggaag cgctaattac gataccttct tacgtttcag
      301 tactgactaa taacgttgag aaaatgaaca gcgtcggatg ggaagacgta atacagaata
      361 gaaaggaaat aagagaataa gatggcgtta attaacccgg tattcctggc gtcatttccc
      421 ttgcgtttta tccccgtcaa aagtggcctt tagcccacgt tggcgctccc gacgttgaca
      481 accagtgagt gtccatagtg tgcgtatgat gtttttaaaa gatcgtcata ctttctgttc
      541 tgcatcaatt ttttcattac aaatgctcgc cataatgccg tcctcaggag gtctcccgac
      601 gtttatgctg cgccgggaga aacaaaaaca acgcataatc tgggacaaat tgatgattaa
      661 aggcaaactg gcgctcgtga cgtgcgcgct gactctggta ttcacttcgt cgcttttcgc
      721 cgcgtcggac acggcagatg gtcgtaccct gaagctggcc attggccctg agccaacgga
      781 aggctttgat cccatgctgg gctggagcca cggcagctac ttattgcttc atgcgccgtt
      841 gcttaagcaa aacgccgata tgagttgggg tgatttactg acggaaaaag tggataccag
      901 ccccgacggt aaaatctgga cgctaacctt aaagcccggg ctgaaattct ccgatggctc
      961 gccattaact gccgaagatg tcgtttttac atacaataaa gcggcgaaga gcggcggtaa
     1021 aattgacatg ggcaatttta gtcatgcgcg agcgctggat gcgcgccgaa ttgagatgac
     1081 gctgagccat ccgcagagca cctttgtgaa tgtactcggg tcgttaggga ttgttccggc
     1141 cagccgttat gatgaaaaaa cgttcgcccg cgaaccgata ggcgccggtc cataccgact
     1201 ggtcagcttt cagccgggtc agcaactgat cgttgaagct aatccctggt atgcgggtaa
     1261 aaagaatgac tttaaccggc tggtttttgt ctttctggat gaagataatg cttatgccgc
     1321 cgcgcgcagc ggacagttgg gactggtgcg cattgcccct tctatggcgg tgaccccgca
     1381 gcaggataat cttaaactct gggtacgcga tagcgttgaa aaccggggca ttgtcttccc
     1441 gatggtgcct gccggtaaaa aggatgctaa cggttatcct gtcggcaacg atgtgaccgc
     1501 tgatgtcgct atcagacgcg caattaacta tgccattaat cgtaagcaac tggcggaaca
     1561 ggtgatggaa ggccatgcga tacccgccta tagcgcggtg cagggattac cgtggcaaaa
     1621 tccttcagtg gtattcagcg atggcgatat tgcaaaagcg cgcgccatcc tggaagaggc
     1681 tggctggaag ataaacagtg cgggcgtgcg tgaaaaagca ggtaaagaag cgcgtctgac
     1741 cttatggtat gccagtggcg acagcacccg acgggatctg gccgaggcgg tgcgcgccat
     1801 gttgcagcgt ttaggcattg tcgtctcgtt gcaatcggga agctgggaaa ctgtagagcg
     1861 ccatatgcac gctaacccta cgctgtttgg ctggggaagt ctggacccga tggaactctt
     1921 ccatcactac agtgggaaag ccgctggtgt ggaatattat aacccgggct attacagcaa
     1981 ccctgcggta gaagcacatc tgaagcaggc tatagatgcg cctgactggc aaaaggcgat
     2041 ccctttctgg cagcaggttg agtgggatgg gaagcagggc gcgggcgtcc agggcgatgc
     2101 ggcatgggca tggctgctta atattcagca tacttatctg gccaacccct gtattgatct
     2161 gggaaaaggc tcgccagaaa tccacggtag ctggtcggtg ttaaacaatc ttgatgactg
     2221 gacctggacc tgtcggtgat gaaattgttc ttcagtcatt ttttgcggct gattattctg
     2281 ttggtgctgg tggctgccgg caccttcatt ttgcttagct tttcgcccgt tgatcctatc
     2341 cgtgcttata ttggcaacga tctgctccat gttccgccag aacaatatgc gcggattgcg
     2401 gcgcgctggg ggcttgacca gccgctgtgg gagcgtttcg gtcactggtt ttggcgtctg
     2461 ctccagggcg acatggggta ttccatgctg ttcaacatgc ctgtcgccag cgtgatccgg
     2521 gaacgttttg cgacgtcatt cgcgctgctg gcaggcgcct ggctattgtc tggtgtgctg
     2581 ggcgtaacat tgggttttct ggccggacgt tttctccacc gttggccgga taagatgatt
     2641 tgccgtatca gctacttatt gtcatcgttg cccactttct ggatagcaat gctgttgctg
     2701 gcgctgtttg ccgtccgctg gccggtatta cctgtttgtt gcgcctggga ccccggaaat
     2761 aatgcaggaa cagctctttt atcggaacgt ttacgccatc ttgtgttgcc ggtatgtgcg
     2821 ttaagtctgt tgggcatggg gcaaattgcg ctgcatacgc gagaaaaaat agccagcgta
     2881 atgaagagcg aatttattcg ttttgcgcgc gctcaggggg ataaaggatg gtcgctgtta
     2941 cgtcaccagg tgttacgtca tgcgattacc ccagcgctct gcttacagtt tgcttctctg
     3001 ggtgaactga tggggggagc gttactggca gaaaaagtct ttgcgtatcc ggggctggga
     3061 caggccacta tcgatgccgg cctgcgtggc gatgtcccgc tactcatggg gatcgtttta
     3121 ttctgtacgc tattagtgtt tgccggaaat acgatttcag cctggcttgt ggtggtgctt
     3181 aatcgatcgc tggagcgtcc cgatgctcta taatcctgcc ccgacgttgt ttcgtctgct
     3241 cctctccgtt acctgtctgc tgtttattgc cggatacggt tatgccacgt tgagccagcc
     3301 gccagaggtt aatctgcttg cccggcatct gtcgcctgat atccagcact ggtttggcac
     3361 cgataatctg gggcgcgatg tatggcttcg ttgctttcag ggggccttca ccagtttaca
     3421 aattggcgtt ggcgccgcgc tgtgcagcgg cgttatcgcg ttagtgatgg cggcagtggc
     3481 gcgcattcat ccccggctgg acctcctggt gcggctgata accgatgcta tgctcgccat
     3541 gccgcattta cttttgctga tccttatctg ttttacgctc ggcggcggta aaagcggcgt
     3601 cattgcggcc gtggcgttaa cgcactggcc ccgtctggcg ctgattctgc gcgccgacgc
     3661 ggagcgggta gcgcagagtg actacctgac attgacctat cgtctggggc atggacacct
     3721 ttattgctgg cgatatcact attttccggc gctattgccg caatggttga cgggaacgtt
     3781 attgatgttt cctcatgcgg tattgcacag cgcggcgtta agttttctgg ggtttgggct
     3841 ggcgccgcat gagccttcgc tggggctgtt gctggcggat gcgttacggt ttattagcca
     3901 tggaaactgg tggctggtgc tatttcccgg cctaatgtta ttcacgctgg tgatgctctt
     3961 cgatcagttt gcgcgcgcca ttcagcggct gtggctaagg agtgacgtat gctgagttta
     4021 caacgggtta cgctggaaag cgcgcgttat cgctggtatg gcgcgagacg ctggtcgccg
     4081 ttattacaga atgtctcttt tgatatcgcg cccggcgaaa tggtggcatt ggttggcggc
     4141 agcggggagg gaaaaagtct gctgctgcaa tgcctgctcg atctgctgcc ggaaaactta
     4201 cgttttcggg gtgagattac gcttgatggc aaccggctgg acagacatac catcaggcag
     4261 cttaggggca atacgtttag ctacgtgccg cagggggtac aggcgcttaa tcctatgctg
     4321 aatatcagaa aacatttgaa cagagcatgt catctgaccg gacgcgcctg ggatgagacg
     4381 cagatggtac agttattaca gcaaagcgat cttgcaccga cagtcctgga acgctttccc
     4441 cgccagctct ccggtgggat ggctaaacga attctggcgt gccacgcctc gctcagccag
     4501 gcacgttata tcctcgcgga tgagatcacc gcctggcttg atacggcact ggcaaaccag
     4561 ttgcttgagc acttgcgagg tctctgcgag cggggatgcg gcgtgctgtg ggtgactcat
     4621 gacctgctgc tggcggcgcg gtatgccgat cgcattgtgg cgctgcatca gggttatatc
     4681 acggacaata ttcgctgtga acgattacag ccggaagaga tgagtgagcc gttaaaacgg
     4741 caatggcagg cattgcctga actaaacccg ttatttatgc cgaccggaga gggaatagaa
     4801 tgctgagctg ccgcgacctc gttattcgtc agggcgggaa agtcttatgg cagaacctga
     4861 cgtttacgat ttctgccggt gaacgggtag gaattcatgc gccaagcgga acggggaaaa
     4921 caacgttggg gcgcgtcctg gccggatggc aaaagccgac gacgggcgac gttctgctgg
     4981 acggcagccc gttacccctg catcagtatt gcccggtaca gctggtcccc cagcatcctg
     5041 aactgacgtt taatccctgg cgaagcgccg gagacgctgt gcgtgatgcc tggcagcctg
     5101 acccggaaac gttgagacgt ttgtatgtgc agcccgagtg gctgacgcgt cggccaatgc
     5161 agctctcagg cggggagttg gcgcgtattg cgatactacg cgcgcttgac ccgcgagcgc
     5221 gttttctgat tgccgacgaa atgacggcgc aactcgatcc gtctattcaa aaagcgatat
     5281 gggtatacgt gcttgaggtg tgccgcagcc gttcattagg gatgttggtg attaatcatc
     5341 agtctgcgct acttgatcaa gtctgtaccc gccatttaca ggtggaatag ccgcaagtcg
     5401 tttctccgca ttgtcgtgtc gccgttaacg caccgggagc ccatgggttc ccggtattgt
     5461 cggcagagat tttactgcat gacgcgttta tctgcgtttt ttgcatcagc ggtattactg
     5521 tagtccctgg tctcttcaac ctgtacaggg gctctgacga ccagacttgg cagcgccagt
     5581 tcgatatcat tctcaatgag tttttcaata atacggatat ttatctcttg ctgaatatcc
     5641 atgtatttat tgtaatccgc ggtattgacg atatgtacca cctcataggt cagccgatcc
     5701 tgaccaaagg ccagtagatg ggcgcggtcg aattgtgttt cgccgacatc ggtaataatc
     5761 tttttcacca tatcgccgat gaggcgtaac ttttccggcg gtgtcgcagt ggcaacgcca
     5821 aaagtaaaca cgatacgacg cgtttgcatc cgcttatagt tgtgtatggt ttgctgcaac
     5881 aactgcgcgt tcgcacaaac gatctgttcg ccgctgaggc tacggatgcg agtggttttc
     5941 aaaccgatat gttcaatcgt accggctaca tcattaaaga cgacgaaatc gccgatctcg
     6001 aagggcttat cgaaaccaat cgacagcgaa gcgaagacat cgctcagaac ggtttgtacc
     6061 gccagggcaa tagcaatacc gcccacgccg aggctggcta ccagtgcggt aatatccacg
     6121 ccgacgttcg ccaggatgga gagcaacatc atagaccaga cgagcacgcg caaaatcata
     6181 ccaagaatga ctaacgtcac cgggttttta ttggagcctg gggcatacag taaatgacgc
     6241 atccatgact gtacgccctg atcaagccaa atcgccattt gaatcgcaac cactaaaaac
     6301 caggcgtgag agagggtaga gaataaccgg tcgggcaggg cgacaaagcg caggctaaag
     6361 agaaatgcgg caaaaaagat gagcatctta ctggtctttt tcagcatctc gaaaacaata
     6421 ggccgcagcc gcccatgagc atcatccttt ttatccgggc gttgtagcgc tttatagacc
     6481 acattaagta gccagttgat gagccagtaa gtaatgaggg tgacgaaaaa aacgaccgcc
     6541 agattgatcc agaacgtcgt tgacatcagc atcgcaacga tatttagtcg tgctaaatac
     6601 tccattttac ctccgatgaa aagcagatga acattacagt atagacgtca catcacggag
     6661 gccgatttcc ggctttacta ttgctgtttt attcagcact tttgttcaaa aagcatgaaa
     6721 aagaggggta gccgtttggc tatcccggcg tttctgtgca gacttatcta ctcctcttaa
     6781 taaaataagg agtcatttat gcaacaagaa catcgagagt gtattgagca gtgttatgaa
     6841 tgcgcggcgg cgtgtgatat ctgcgcctct tcttgtctgc gtgaagataa cgtcgaaatg
     6901 atgaagcatt gcatcgagtt agatatgcaa tgtgcggcca tttgtcgcct ggcggcgcaa
     6961 tttatggcat tggaaagcga gtactcacaa aaattatgcc gcctgtgcgc ggatatctgc
     7021 aaagcctgcg ccgaagagtg tgcaaggcac gatcacgacc attgccagaa ttgcgcgcgg
     7081 gcatgcagcc aatgcgcaga cgcctgcctt aaaatggccg cgtaattttt cttccgccat
     7141 tagctcaacc ggatagagca tagagcttct acctctaagg ttcggggttc aattcctcga
     7201 tggcggacca gttgatatca aaaaaggcca cctgcgcggt ggccgctgag tttctgttga
     7261 aataaatgca atgttataat ataacaatca tctttctaag aaagatgagg gtaacgtttt
     7321 ggtgattcat ttaaaaaaac tgacaatgct tctgggaatg ctgttggtca atagtcctgc
     7381 cttcgcgcat ggtcatcatg ctcatggcgc gccgatgacg gaggttgagc aaaaagcggc
     7441 agcgggtgtg tttgatgacg ctaatgtacg cgatcgcgcg ctcaccgact gggatggtat
     7501 gtggcaatcc gtctatcctt atctggtcag cggcgagctg gaccctgtct tcagacaaaa
     7561 ggcgaagaaa gacccggaga aaacgtttga ggatattaaa gcgtattatc gcaaaggata
     7621 cgcgacgaat gttgagacta tcggtattga aaatggcgtt atagaattcc atcgcgacaa
     7681 taacgttgca tcctgtaaat acaattatgc cggctataaa attctgactt acgcatcggg
     7741 taaaaaaggg gtgcgctacc tgttcgaatg taaagatgcg aatagcaaag cgcctaaata
     7801 tgttcagttt agcgatcata tcattgcccc gcgcaaatcg gcgcacttcc atatctttat
     7861 gggaaatacc tcgcaacagg cattgttgca agagatggaa aactggccta cctattatcc
     7921 ttatcagtta aaggcgaatg aggtcgttga cgaaatgcta catcattaag tctgattgca
     7981 atgttaaaag ctcgctatga atagcgagct ttttttctgc cgttatgcca tatttctggc
     8041 aatcaatata aaaaatacct gcgcccccgg agcaacgatg acgctgtcca taccgccctc
     8101 gattcaatgc caaacggaag cggcgtgtcg cctgattact cgtgtcacag gcgatacgtt
     8161 gcgtgctatt catttatatg gttccgctgt cgcgggcgat ctgaagccaa acagcgacat
     8221 tgatctgctg gtgacaatat gccagccgct gacggagacc caacgcgcaa cgctgatgca
     8281 ggaattgctg gcgctttcat cgccgccggg ggcgtcagca gaaaaacgcg ctctggaggt
     8341 cactgtcgtg ctttattcgc agctggttcc ctggtgtttt ccaccttccc gggaaatgca
     8401 atttggcgag tggctaagag aggacattta tcaggggatt tatgaaccag cgcagcagga
     8461 ctgggacatg gtgttactga taacccaaat tctggaaacc agtataccgc taaagggaga
     8521 acgcgcggaa cggctgttca cgccagcccc tgcggcgcag ttgctgaagg ccttgcgtta
     8581 tcccctcgac ctttggcaat ccacggcaga tgtgcaggga gatgagtatc atatcgtttt
     8641 aaccctggcg cgtatctggt acaccctttc taccgggaga tttacctcta aggatgcggc
     8701 ggctgactgg ctgttacctc agttgccaga agagtatgct gctacgttgc gtgcggcgca
     8761 gcgtgaatat ttaggtctgg agcaacagga ctggcatatt ttgctgcctg cggtcgtacg
     8821 ctttgtggat tttgcgaaag cgtacatccc cacgcagttc acataagatg ccccaggacg
     8881 tctgtcaggt tgcgcaaacg gcgttcctca actactactt aataggttct catcgctgaa
     8941 gtaagcagat gatcttatgc gggccatcga atggatattc ccacatggct ctcgttttgt
     9001 tgaggtggat atgactggtt ccgcatcatc tgttttaaag acagatacaa gactattgag
     9061 cgaaaacctg tttcttaatt atggtctgga gtccttattt aaggacgtcg caataatagc
     9121 tggcaacgta aattatattg tttttgatat cgacgattac tacaccgtac agcagtatat
     9181 tacttccaca tttaaaacgg tactcattgg gattgttacc cataatgaat ataactttat
     9241 tgatgaacat catgctatat atcgaataaa ggtcgatgcc tctattgctg agtggcgcga
     9301 attactgatt ttggccgctg ctggtcaatt ttttcccaga tcagagaaag tcagattaac
     9361 ggcgaatgaa agaaatgttt tggcgatgct tgttaaagga atggatatcc gacaaataag
     9421 ctgtgagctg aatgtacatt taaaaactat ttactcagta cgctaccatg tcctgactaa
     9481 attaggttgt agaacagttc tggattatca aatactgtcc gtctctaaag cctttacgca
     9541 ctggcttaca ataaataatg tcgataatgt aattttccgt gtaaatagca aggtcattgc
     9601 ttaataatga tttgcttctg atggcgttta ggttcactat gctttcttac atcatcatga
     9661 ggccagacag gcatggctac ttttagtatt agcgcaatgg cggcgcagtg tggtgtcaca
     9721 acagcaaata tcaggtcctg ggaacgctat ggcctgcttc aacctaccaa agatgaagct
     9781 ggcaatcgtt tttattgcat agaagatgct atcagaatac agcatattat cgacgcgtta
     9841 agcaaaggct tctcattaaa agagattaaa cctgccctct atggtgaaga aacgcattgc
     9901 cgctcgggat ggttattcta ccaggaagag attttagcgc agtgtagaaa attcgaaccc
     9961 gccaaattgc gaaaattact ctggcgttat ggtcgggaaa ttccgccgtg tatcgtaatt
    10021 gagtcaatac tgcgtccttt atggctgtgg ttgtccgcag gcgatgatga tgcacgccga
    10081 tttgaaaagg cattactgga tactgcgatt attgaatacg ccacgttcca gctaagtagc
    10141 gtacgaaagg cgccagcagg cacaatgctt attgctgcgt tttcgctgaa cgaccccatt
    10201 gagctatggc tggaaacgat taaatattgt agtgaaggta tgcgagttga agtcatcccc
    10261 tggcaggcgc cgatgcccga tcttttatca acgtctttcg agcatattgt tttgtggcat
    10321 gatgagacat taactcccgc ccaggaaaat cttattcagg ctttaaaaga atcgggtaaa
    10381 tttagtcttc atgtgaaaaa tggctcaggc ttaacattac tgccagccgt ataccggcag
    10441 catgagatgc ccgaaagcat gcagcatgtt gcaccgcaaa tccatgcaaa cggctacgaa
    10501 aaatcaggca ccgcacgttg aggcatctgc attattaacg aacaggggag gagtaacccc
    10561 ctcccttgtt tatacccttc atacttcaag ttgcttatgt gttggctacg gattactcgg
    10621 cccatccata ggcctcgccc tgacgggccg tcgcaagcga cgttcaaatc tgctcccggc
    10681 agatttgtcg ttcaccccag tcacatagtt atctatgctc ctggggactc actcccttgc
    10741 cgccttttag caacacgaat tattttgggt atatattaga tgtcgtcagg tgtctgaaaa
    10801 aaaacggctt ctaaggcatt gcggtaaata tcaagctgca ctacgtcttt ttctgtttcc
    10861 agtttttcaa taagtttggc gatgatatcc ttatttgaga catgctgctg cgattgcaat
    10921 agttcgtaag taatttcctg aatagctcgc tgttcacata acatatgtgc agaaaaagga
    10981 ttgccagtac tattttgttc gttgactagt gtaatggtag tcatatttca ccatattcga
    11041 tgtaaattga agccgatctc cctgagcggg ggagagaaat tagtgaccta tta
//
LOCUS       DAJVKX010000142        11083 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.142, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000142 DAJVKX010000000
VERSION     DAJVKX010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11083
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.142"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(11..730)
                     /locus_tag="OPY25_003794"
     CDS             complement(11..730)
                     /locus_tag="OPY25_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HCS0929295.1"
                     /translation="MMRKTLLAAVLTFTAMAAHADYKCSVTPRDDVILSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYTLSAAQREQAKDYQAELRSALPWIDEGARSRVEKGRVAL
                     DKIIAKEVGESSNMRSRLTKLDAQLKAQMNRIIEHRTDGLTFHYKAIDQVRADGQQLV
                     NQAMGGILQDSINEMGAKAVLKGGGNPLQGVMGSLGGLQTAIQNEWKNQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGSLK"
     gene            complement(780..1106)
                     /locus_tag="OPY25_003795"
     CDS             complement(780..1106)
                     /locus_tag="OPY25_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HCS0929296.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINDVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEARNLEEVRTSEL
                     FDVWWD"
     gene            complement(1106..1825)
                     /gene="trmB"
                     /locus_tag="OPY25_003796"
     CDS             complement(1106..1825)
                     /gene="trmB"
                     /locus_tag="OPY25_003796"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCS0929297.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEAPVDFATLFGREAPVTLEIGFGMGASLVAMAKARPEQNFLGIEVHSPGVGA
                     CLASAHEEGVENLHVMCHDAVEVLHKMIPDNSLSMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVLSKLKLGGVFHMATDWEAYAEHMLEVMSSIDGYKNLSESNDYVPRPESRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            1980..3032
                     /gene="mutY"
                     /locus_tag="OPY25_003797"
     CDS             1980..3032
                     /gene="mutY"
                     /locus_tag="OPY25_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCS0929298.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQINKTPYKVWLSEVMLQQTQ
                     VTTVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     EFPQTFAEIAALPGVGRSTAGAILSLALGKHYPILDGNVKRVLARCYAVSGWPGKKEV
                     ENTLWTLSEQVTPARGVERFNQAMMDLGAMVCTRSKPKCTLCPLQNGCIAAAHESWSR
                     YPGKKPKQTLPERTGYFLLLQHNQEIFLAQRPPSGLWGGLYCFPQFASEDELREWLAQ
                     RHVNADNLTQLNAFRHTFSHFHLDIVPMWLPVSSLDACMDEGGALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            3060..3335
                     /locus_tag="OPY25_003798"
     CDS             3060..3335
                     /locus_tag="OPY25_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HCS0929299.1"
                     /translation="MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK"
     gene            3448..4533
                     /gene="mltC"
                     /locus_tag="OPY25_003799"
     CDS             3448..4533
                     /gene="mltC"
                     /locus_tag="OPY25_003799"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HCS0929300.1"
                     /translation="MMKKLLALAVIAPLLISCSSSTKKGETYNEAWVKDTNGFDILMG
                     QFANNIENLWGYKEVLIAGPKDYVKYTDQFQTRSHINFDDGTITVETIAGTEPTAHLR
                     RAIIKTLLMGDDPTSVDLYSDVDDIKISKEPFLYGQVLDNTGQPIRWEGRATTFADYL
                     LKTRLKSRSNGLRIIYSVTINLVPNHLDKRAHKYIGMVRQASRKYGVDESLILAIMQT
                     ESSFNPYAVSHADALGLMQVVQHSAGKDVFRSQGKSGTPSRNFLFDPASNIDTGTAYL
                     AMLNNVYLSGIENPTSRRYAVITAYNGGAGSVLRIFSNDKIQAANMINRMSPGDVYQI
                     LTTRHPSAESRRYLYKVNSAQRSYRRR"
     gene            4750..6006
                     /locus_tag="OPY25_003800"
     CDS             4750..6006
                     /locus_tag="OPY25_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease"
                     /protein_id="HCS0929301.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPTLLGIVADKWLSAKWVYALCHVVGAITLFMAAEVTTPGAMFFVILLN
                     SLAYMPTLGLINTISYYRLQSAGMDIVTDFPPIRIWGTIGFILAMWGVSFSGFELSHM
                     QLYIGATLSVLLVLFTFTLPHIPVANQQKNQSWTSMLGLDAFALFKNKRMAIFFIFSM
                     MLGAELQITNMFGNTFLHSFDKDPLFASSFIVQHASVMMSISQISETLFILTIPFFLS
                     RYGIKNVMLISIVAWMLRFGLFAYGDPTPFGTVLLVLPMIVYGCAFDFFNISGSVFVE
                     KEVRPEIRASAQGMFLMMTNGFGCILGGIVSGKVVEYYTQNGITDWQTVWLIFAGYSL
                     VLAFAFVALFKYKHVRVPASSQPVAH"
     gene            complement(6068..8193)
                     /locus_tag="OPY25_003801"
                     /pseudo
     CDS             complement(6068..8193)
                     /locus_tag="OPY25_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
     gene            8618..9325
                     /locus_tag="OPY25_003802"
     CDS             8618..9325
                     /locus_tag="OPY25_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCS0929302.1"
                     /translation="MVIGPFINAGAILFGGVIGALLSQRLPERIRVSMTSIFGLCSLG
                     IGILLVMKCANLPVMVLATLVGALIGEFCLLEKGINGAVAKIQQLFMASGKKPTHDSF
                     IQSYVAIIVLFCASGTGIFGAMHEGMTGDPNILIAKSFLDFFTAIIFACSLGIAVSAI
                     CAPMLIIQLTLAACATLILPLTTPAMMGDFSAVGGLLLVATGLRVCGIKMFPVVNMLP
                     ALLLAMPISAAWAMFFA"
     gene            9431..9506
                     /locus_tag="OPY25_003803"
     tRNA            9431..9506
                     /locus_tag="OPY25_003803"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9464..9466,aa:Phe,seq:gaa)
     gene            9667..10480
                     /locus_tag="OPY25_003804"
                     /pseudo
     CDS             9667..10480
                     /locus_tag="OPY25_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009114529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
BASE COUNT         2631 a         2960 c         2755 g         2737 t
ORIGIN      
        1 aaaggaaaga ttacttcagg ctgccaacca gcgctttgcg gctatcttct aaggtcacta
       61 cgcggctaca gacatctttg ccaaactgct ggaaatcttt ctcctggttt ttccattcgt
      121 tctggatagc ggtttgcaaa ccaccgagac tacccatcac gccctgtaaa ggattgccgc
      181 cgcctttaag caccgctttg gcgcccattt cgttaatgct gtcctgcaaa ataccgccca
      241 tcgcctgatt caccaactgc tgaccgtcgg cacgcacctg gtcgatagcc ttatagtgga
      301 acgtcaggcc gtccgtacga tgttcgataa tgcggttcat ttgcgctttt aattgcgcat
      361 caagcttcgt caggcggctg cgcatgttgc tgctttcgcc cacctcttta gcgatgattt
      421 tatccagcgc cacgcggcct ttttcgacgc gcgatcgggc gccctcatca atccacggca
      481 gcgcgcttcg cagttccgcc tggtaatctt tcgcctgctc gcgctgcgcg gcgctaaggg
      541 tgtactgctt accgttgtac atcacattgc cgtccggcgt gatcaccagg ttgccgtttt
      601 cacctttcac ctgcaccgtt tgtggactca ggatcacatc gtcacgcggc gtgacgctgc
      661 atttgtaatc tgcatgagcg gccatcgccg taaacgttag cactgccgcc agcagcgttt
      721 tgcgcatcat aactttccct caagacaaag cgggccggca tttgccgacc ctgtacttat
      781 tagtcccacc aaacgtcgaa aagttcgctg gttcggactt cttcaaggtt gcgcgcttcc
      841 agccacttac gcacaatcgc ctgatgttct tcggtacatt taccgatttc ctgcatacaa
      901 atcagccctt cccaggccag gtagccgctg ccgtcaaacg ccagtttatt aggctcaata
      961 acgtcattaa taaagtcatc gacagtctta tcgatctgct cttcagatgt accttccgga
     1021 aaacgccatg ccaccgaaaa tcctaattcc tggaattcgt caatgtgcat ttttttacgc
     1081 agacgacgac tacggttctt tgccattatt tcaccctctc gaacattaag tcccatacgc
     1141 catgaccaag acgatggcca cgttgttcaa atttcgttac cgggcgcgat tccgggcgcg
     1201 gtacataatc attgctctct gacagatttt tgtacccgtc gatagaagac atgacttcaa
     1261 gcatgtgttc cgcatacgct tcccagtcgg tcgccatatg gaaaacgccg cccaatttca
     1321 gcttgctcaa taccagttca gcaaacggca cctgaacgat acggcgttta ttatgacgcg
     1381 ctttatgcca cgggtcaggg aaaaagagct gaaccatcga taaagaattg tcaggaatca
     1441 ttttatgcaa cacttctacc gcgtcgtggc acatgacgtg caggttttca acgccctctt
     1501 catgagcgga cgccagacac gcgccgacac cgggtgaatg cacttcaatg ccgaggaaat
     1561 tctgctccgg gcgcgctttc gccatcgcca cgagagacgc ccccatgcca aaaccaatct
     1621 ccagcgtcac cggcgcttcg cgaccaaaca acgtggcgaa atctaccggc gcttcgctga
     1681 actcgacgcc catcaccggc cagtagtttt ccagcgcgtg ctcttgcccc tttgtcagtc
     1741 gcccctggcg acgaacaaaa ctacgaatac ggcgcagcgg gcgaccgttt tcatcaaatt
     1801 ccggtgaaat gacgtcgttt ttcataaaag tgtagtctgc tgtgtttgag ttctgaaaac
     1861 gggcattatc caaagttagt tgccggatgc aagcatgaag cgcactgcgg aaagttccgg
     1921 tttacaccct gcggcctctg tgctgcaatc ttgcccccgg caataatgaa tgagtttcca
     1981 tgcaagcgtc tcaattttca gcccaggttc tggactggta cgacaaatac gggcggaaaa
     2041 cgctgccctg gcaaattaac aagacgcctt acaaagtatg gctctcggaa gtcatgttgc
     2101 aacaaacgca ggtgacgacg gtgattcctt actttgagcg atttatggcg cgctttccga
     2161 cggtaacgga tttagcgaat gcgccgctgg atgaagtgct ccatttatgg accgggctcg
     2221 gctattacgc ccgcgcgcgt aatttgcata aagcggcgca acaggtagca acgcttcacg
     2281 gtggagaatt cccgcaaact tttgccgaaa tcgccgcgct ccccggcgtc gggcgttcaa
     2341 ccgccggcgc gattctctcc ctcgcgttag gtaaacatta tccgattctt gatggaaacg
     2401 ttaaacgtgt gctggctcgc tgttatgctg ttagcggctg gcctggaaaa aaagaggtgg
     2461 agaatacgct gtggacgctg agcgagcaag tgacgcccgc acgcggcgtg gagcgtttta
     2521 atcaggcgat gatggatctg ggcgcgatgg tttgtacgcg ttcaaagcca aagtgcaccc
     2581 tgtgtccgct gcaaaacggt tgtatcgccg ctgcgcatga aagctggtca cgctatccgg
     2641 gcaagaaacc gaaacagacg ttgccggagc ggacgggtta ctttttattg ttacagcata
     2701 atcaggagat tttcctggcg cagcgccctc ccagcggttt atggggcgga ctctactgct
     2761 ttccgcagtt cgccagcgaa gatgaattac gtgaatggct ggcgcaacgg catgttaacg
     2821 ctgataattt gacccagctt aacgcgtttc gccacacatt tagccatttc cacctggata
     2881 ttgtgcctat gtggcttccc gtgtcgtcac tggacgcctg catggatgaa ggcggcgcgc
     2941 tctggtataa cttagcgcaa ccgccgtcag tcggactggc ggcccccgtg gagcgcttgt
     3001 tacagcagtt acgtaccgga gcgccagttt aacgccccgg tcgatgaaga ggatgactta
     3061 tgagcagaac gattttttgt acttacctgc aacgcgacgc tgaagggcaa gattttcagc
     3121 tctaccctgg cgaactagga aaacgtatct ataacgagat ctctaaggac gcgtgggcgc
     3181 agtggcagca taagcagacc atgttgatta acgagaaaaa gctcaacatg atgaacgccg
     3241 agcaccgtaa actgctggaa caggagatgg tgagcttcct gttcgaaggc aaagacgttc
     3301 atatcgaagg ttatacgccg gaagataaaa aataggcccg ttgctgaatg aggctgcgct
     3361 tattcggcct gtgagttatg ccggataagc ccttagcgcc gctgcccggc aacatggcat
     3421 aacgacaaca caacatgcac tcccggaatg atgaaaaaat tactcgcgct tgctgttatt
     3481 gcgccgttgc tcatctcctg ctccagttcg accaaaaaag gcgagacgta taatgaagcc
     3541 tgggtcaagg ataccaacgg ctttgatatt ttgatggggc aatttgccaa caatattgaa
     3601 aatctgtggg gatataagga agtcctgatc gccgggccga aagactacgt caaatatacc
     3661 gatcagttcc agacccgtag ccacatcaac tttgatgatg ggaccattac cgttgaaacc
     3721 atcgccggga cggaacctac cgcacatctg cgccgggcca ttattaaaac gttgctcatg
     3781 ggtgacgacc caacctccgt cgatctttac tccgatgtcg atgacataaa aatttctaaa
     3841 gaacccttcc tgtatggtca ggtcctcgac aataccggcc agcctattcg ctgggaaggc
     3901 cgcgccacga cattcgcgga ttacttgctg aaaacgcggc tcaaaagccg cagtaacggc
     3961 ctgcgtatta tttacagcgt caccattaat ctggtgccga accaccttga taaacgcgcg
     4021 cataaataca ttggcatggt acgccaggcc tcccgtaaat acggcgttga cgagtcgctg
     4081 attctggcga ttatgcaaac ggagtcctcg tttaacccgt atgcggtcag ccacgcggat
     4141 gcgctgggcc tgatgcaggt agtgcaacac agcgccggga aagatgtttt ccgttctcag
     4201 ggtaagtccg gcacgccaag ccgtaacttc ctgttcgacc ccgccagcaa tatcgatacc
     4261 ggcacagcgt atctggcgat gttgaataat gtctatctga gcggtatcga gaatccgacg
     4321 tcgcggcgct atgcggtcat tactgcctat aatggcggcg caggcagcgt attacgcata
     4381 ttctcgaacg ataagattca ggccgcgaat atgattaacc gcatgtcgcc gggggatgtg
     4441 taccagatat taaccacccg acatccatct gcggagtcgc gccgctatct gtataaggtg
     4501 aattccgccc agcgatcgta tcgccgccga taaaccatcg catcccgcct ctggccagca
     4561 aatgacagag gcgggaaagg caaaagtgtt aactccgtca cccttttgct ttgcaatcag
     4621 aaattgtttg caaatatttg tcacaggtaa caaaaaaagc ccgcctctca ttgatagaat
     4681 cacaccaaat cacaacggca aatgtgcctt ttaaaacatt catccgctct caggtgtgag
     4741 gaaattaaca tgaatcttaa gctgcagctt aaaatactct cttttctgca gttctgtctg
     4801 tggggaagct ggctcactac cctgggctcg tatatgttcg tcaccttaaa atttgacggc
     4861 gcatctattg gcgcagttta tagttcactg gggattgctg ccgtctttat gccgaccttg
     4921 ctaggcattg tggctgacaa atggctgagc gcgaaatggg tctatgccct gtgtcatgtc
     4981 gtcggcgcca tcacgctatt catggccgcg gaagtcacta cgcctggggc gatgttcttt
     5041 gtgatcctgc ttaactcgtt ggcttatatg ccgacgttgg gcttgatcaa tactatatcg
     5101 tattaccgcc tgcagtctgc cggcatggat attgtgactg actttccgcc tatccgtatc
     5161 tggggcacca tcggctttat tctggcgatg tggggcgtga gtttctccgg tttcgagctg
     5221 agccatatgc agctttatat cggcgcgacg ctttccgttc tgctggtact gtttaccttt
     5281 accctgccgc acattccggt ggcgaaccaa cagaaaaacc agagctggac atcaatgctg
     5341 ggccttgacg cttttgcgct gtttaaaaac aagcggatgg cgattttctt catcttctcc
     5401 atgatgctgg gcgcggaact gcagatcacc aacatgtttg gcaacacctt cctgcatagc
     5461 tttgataaag atccgctatt cgccagtagc tttatcgtgc agcacgcctc ggtgatgatg
     5521 tcgatttcgc agatttctga aacgttattc atcctgacca ttccgttctt cctgagccgt
     5581 tatggtatta agaacgttat gcttatcagt attgtggcgt ggatgctgcg tttcggcctg
     5641 ttcgcttatg gcgacccgac gccgttcggt accgttctgc tggtattgcc gatgattgtg
     5701 tacggctgcg ccttcgactt cttcaacatt tctggctcgg tgtttgtcga aaaagaagta
     5761 cgcccggaaa tccgcgccag cgcgcagggg atgttcctga tgatgaccaa tggcttcggc
     5821 tgtatccttg gcggcattgt gagcggtaaa gtggtggagt attacactca aaacggcatt
     5881 accgactggc agaccgtgtg gctcatcttc gcaggctact cgctggtgct ggcctttgcg
     5941 ttcgtagcct tgttcaaata caaacacgtt cgcgttccgg caagttcgca acccgttgca
     6001 cattaatcct tgccctgttt cgcaggccgg ataaggcgta aatgccttat ccggcctgca
     6061 ggcaacgtta ctttaaaaca tatccataca agcgtttaat tccatcggca tcggtctcgc
     6121 tatatacccc ctgcaattcc ggcgaaaaac cgagcaacag attgatgccc tcttccagcg
     6181 ccaaaaaata acgctgcgcc gcgccacccc aaatctcccc cggcaccacg cacagtacgc
     6241 ccggcgggta tggcaatgcc ccctcggcag caatacgccc gcccgcctcg ctgatacgca
     6301 ccagctctac atcgccgcga ataaaggcgc tgttggcatc ctgcgggttc atcgccacat
     6361 gcggcaggct ttctttgcga aacatcgctt tttgcagatc cttaacgtca aagctaacgt
     6421 acaggttgtg catctcctga catagctcac gcagggtgta atcgcggtag cgcaccgggt
     6481 atttctgaaa aaccgtcggc aatacatccg caagcggcgt atcgtcttca atgtgccgtt
     6541 caaattgcgc cagcatcgcg accagtcgcg ccagtttctc ttcgctctcg gcgggtgtca
     6601 gcaagaatag aatcgagttg agatcgcact tctcaggcac aataccgttc tcacgcagat
     6661 agtgggcgag aatggtcgcc gggatgccga attcggtgta ccgcccacta tcggcatcaa
     6721 tacctggcgt ggtcagtaac agtttacaag gatcgacaaa atactggtca tccgcataac
     6781 cctcaaagcc atgccatttc gccccgggct caaaactgaa gaaacgacga ttgctggcaa
     6841 tggtctccgt cggatatgcc tgccacggct tgccgtcaac caccagtggg ataaagggct
     6901 gaagcagttt gcaacgggcg agaatggctt tacgcgcgtc aatgcccagc gcaacgcact
     6961 ccgcccacag gcggcgaccg ctctcccctt cgtggatttt ggcattgaca tccagcgccg
     7021 caaacagcgg gtagaacgga ctggttgaag catgcaacat gaaggcgttt gtgcgggcaa
     7081 aaacgcgcct ggccgcgaat atggttatct tttttgtgga tctgcgaggt ttgtgagaac
     7141 cccgcctgtt gcttatgtac cgattgggtc acaaagatcc cagggtcgtt ttcattaagc
     7201 tccagccgca acggcgaggt atccgccatc atattgataa actgctcata gcctacccac
     7261 gcggagtcaa acagaatgta atcgcagaga tgcccgattt tatccaccac ctgacgggcg
     7321 ttgtaaatag tgccgtcata ggtacccagc tgaatgatcg ccaggcggaa cggacgcggc
     7381 gcatcggcgc tttccggcat cacgtcacga atctggtcgc gcaggtacgt ttcatcaaaa
     7441 cagtgcgcat caataccacc gataaaacca aacgggttac gcgccgcctc aagatagacc
     7501 ggcgtcgccc cggcctgaat cagggcgccg tggtggttgg atttgtgatt atttcgatca
     7561 aacagcacca gatcgccgcg cgtcagcaag gcgttggtga ccactttatt cgccgccgaa
     7621 gttccattca gcacaaagta ggttttatcc gcattaaaca cttttgccgc aaatttctgc
     7681 gcgtgtttgg cagaaccttc atgtattagc agatcgccaa gtttcacatc ggcgttacac
     7741 atatccgcac gaaacaggtt ttcaccaaaa aagtcataaa aatggcggcc tgcgggatgt
     7801 tttctaaaaa actcgccatg ctggtgcccc gggcaagcaa aggtactatt ccccatgtcg
     7861 acatactggg tcagggtgcc ataaaagggc ggcagaagtt ccgcttcgta gcgacaggca
     7921 gcgttttcca gctccagcca ttcctgcgcg ttcccgccga ttaccgccgt aacgccgaca
     7981 ggcgcgctga cgggttcatc cgcaagcata aataccggca ggtgaaaacc ggtgcgttta
     8041 agcaacgcca gaataccgct acggctgtcg gcagtggtaa tgacgactgc ggccacatcg
     8101 gtaaagtcgg tactttccag tgccactacg tttcggtggg tggagagacg gggggatgag
     8161 ttcaccgctg gcggcaatat tcattgattt cataagcgca aatacccgtt tcgggagtag
     8221 agtaaccccg gacaaggccg atgccttgcc caacgagatg ccgggtcaaa ctggatacca
     8281 gctccgaccg ccagacatca gtaaaaacag actgtttctg attttactgt tgtcctgcag
     8341 tgagcgtgcg ctgccctcac cgcatagcgg ggatgacaaa aaaaaggaaa gaaaggggca
     8401 aacctcgcgc agtcaggcga cagtgaagac aatataaagg cgctatgttc atcccggcga
     8461 gccccatgct ggcaggagaa atttcgcgca atcatggcac ctttcaccag acggcgcaag
     8521 gtaaaatcag cgctctatac gtcacagata atcaagctat taacagctta atcgcgtgat
     8581 aataaggcaa tttgaaagac aaataacagg agtcattgtg gtaattggac cttttattaa
     8641 cgctggcgca attttattcg gcggcgttat tggcgcgctg ttaagtcagc gtctgccaga
     8701 acggattcgc gtctcaatga cgtctatttt tggtctgtgc tctctgggta ttggcattct
     8761 gctggtgatg aagtgcgcta atcttccggt gatggtgctg gcgacgctgg tcggcgcgct
     8821 tatcggcgag ttttgtttgc tggaaaaagg cattaatggc gcagtcgcga aaatccaaca
     8881 attatttatg gcatcgggta agaagccgac acacgactct tttattcaaa gttacgtcgc
     8941 tatcattgta cttttttgcg ccagcggcac cggtattttc ggcgcgatgc atgaagggat
     9001 gaccggcgat ccaaacattt tgatcgctaa atcttttctg gattttttta ctgccattat
     9061 tttcgcctgt tcgcttggca tcgccgtttc ggcgatttgc gcaccgatgt tgattatcca
     9121 gttaacgctt gccgcctgcg ccaccctcat tcttccactg actacgccgg caatgatggg
     9181 cgactttagc gccgtgggcg ggctgctgct ggtggcaacc ggcttgcgtg tatgtggaat
     9241 caaaatgttt ccggtagtga atatgctccc ggcgctgttg ctggcgatgc cgatctccgc
     9301 cgcatgggcg atgttttttg cctgactctg cgtgcaataa caacaaagtg gtgatagatt
     9361 gtgcagtcta cgttgatttg aagaaatttc gttgacgaag cgaggcgatt acggtttaat
     9421 gcgcctcgtt gcccggatag ctcagtcggt agagcagggg attgaaaatc cccgtgtcct
     9481 tggttcgatt ccgagtccgg gcaccacctt tcctttttta cacttcctta taaatcccca
     9541 tgtgttttta attcaatgag ttagtggaaa aactcttccc agcgaatttc tatttatccg
     9601 cccaaatcag gggcttttgg tggtcaactc ggtgctcagt tcggttagat aaaggagtgc
     9661 cctcaaatgg cattaaccga caaacaagca cgtagtgcaa agccttctga taaaccctat
     9721 aaactcgttg atacactcgg cctgtatctt ctggtaaaac ccaacgattt tcgtatctgg
     9781 tatttcaaat atcgttttga gggaaaagag tccggggtat cattcggtcc ttatcccgaa
     9841 acctcattcg cccttgtccg cgaaaaacgc gatgccaccc ggcgcgtact aaaatccggc
     9901 tttacccctt ctcagcagcg ccgggacgaa aaaaggttgt caatgaatta gaacgttcca
     9961 gtacatcgct agattgtggc ataccggctg cctgaaactc tggtcagaaa gtcactccaa
    10021 taaaattcct gtctgcctcc aacactacgt tttccctgat atcggcgcaa tgggtatttc
    10081 ggcgacttaa accctacatc tcgcacgact ggtcagagac attgatgata aaggtgtgca
    10141 tgttgttgcc ggacgtatac gccagcatct gaccaaaatt atgcgccacg ccgtacagca
    10201 gggaacgatt aaatataatc cggcattcga tctggatggc gttgtaactc ctgttataac
    10261 ccagcatcac cccgcccttc ccctgaaacg cctgcctgaa ttgctgggct atatcgacac
    10321 ctacaacaag gccggatacc ggctatcaac actttccggt atgccgcact gccaggacaa
    10381 caccaaacgt gagttcacac atctggttag agtttctctg gcttaccgca aaattgagtg
    10441 ggaacacgtt tcaacaggca cttcaggtgc tgatgactga cgtgcgccgc tggaagcata
    10501 agagtaaatc cacagcattc cgccttaatg gtgggatgct gtttttgtcc gggaacggag
    10561 acaaaaagcc cgtgccagca atgagttacg tctgttacgt ttcatatatg ggagatggtg
    10621 gatgccggaa actttggcgg tagcgtgcct gaagcggctg tcctccccat tgccactgcc
    10681 acgagcgtac cgtggttcct ttttcgccaa taaatccaga ataaggttat gtcacaaaat
    10741 ggcctgcgtt ttacgctgga tgtggacgga ttaacgccgg cggcaaccac tgtcgtcagc
    10801 ttcaccctcc agaggtatca acagttcaac aggtgcaagc tggaataaga atgaaagact
    10861 aaaaacacca gatgatgcat ccaatgatag cattaaatca ggccatggtt cacaggagga
    10921 aatattacca tcttaccttt acttaataag atcattttta atgaaaatag gtttatcaat
    10981 aaaacaaaaa atattcttga cagcgaaatt gcatcttttc ttgcatcttc aagtcaggaa
    11041 ggatttgatt tagtggatga taacaataat tatctttttg atc
//
LOCUS       DAJVKX010000143        10611 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.143, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000143 DAJVKX010000000
VERSION     DAJVKX010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10611
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.143"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(11..82)
                     /gene="ypdK"
                     /locus_tag="OPY25_003805"
     CDS             complement(11..82)
                     /gene="ypdK"
                     /locus_tag="OPY25_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HCS0929303.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(485..1405)
                     /gene="lpxP"
                     /locus_tag="OPY25_003806"
     CDS             complement(485..1405)
                     /gene="lpxP"
                     /locus_tag="OPY25_003806"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HCS0929304.1"
                     /translation="MFPQSKFSRAFLHPRYWLTWFGVGVLWLLVQLPYPVLRFLGTRT
                     GKLARPFLKRRESIAQKNIELCFPTLSREEREKLIAENFHSLGMALLETGMAWFWPDS
                     RVRKWFDVDGLDNLTRAQAQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNPL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGPKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKSDNSGYRLYITPEMEGYPADENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPLGEASLYI"
     gene            1926..2168
                     /locus_tag="OPY25_003807"
     CDS             1926..2168
                     /locus_tag="OPY25_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HCS0929305.1"
                     /translation="MIYLWTFLAISILAVSGYIGQVMGAFSAVSSFTGMVILAALIYL
                     LNVWLQDGDDIVSGLLLFLAPACGLIIRFMVGYGKR"
     gene            complement(2407..3798)
                     /gene="pgtP"
                     /locus_tag="OPY25_003808"
     CDS             complement(2407..3798)
                     /gene="pgtP"
                     /locus_tag="OPY25_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate transporter PgtP"
                     /protein_id="HCS0929306.1"
                     /translation="MLTILKTGRSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIV
                     RNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLV
                     LCVIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
                     SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLP
                     SLEQMMPEEKVILKTKNTAKAPENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGM
                     ISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMPLAMICMA
                     LIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGF
                     MSYIFGASLGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNA
                     LHNQDSLQLADAQ"
     gene            4234..5427
                     /gene="pgtC"
                     /locus_tag="OPY25_003809"
     CDS             4234..5427
                     /gene="pgtC"
                     /locus_tag="OPY25_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate transport regulator PgtC"
                     /protein_id="HCS0929307.1"
                     /translation="MFGSCQAYSRELVMATTFSPSATAWIIQRWQTEPGSVMIRTLNR
                     TSGSLEQLLDTANAENVDLILTSSPMLLQHLQEHQKLALLDSAPAASQKLVPRSIRST
                     SVAVAVSGFGLLINRSALAARHLPPPADWQDMGLPSYQGALLMSSPSRSDTNHLMVES
                     LLQQKGWTAGWATLLAISGNLVTISSRSFGVADKIKSGLGVAGPVIDNYANLLLNDPN
                     LAFTYFPYSAVSPTYVAVLKNSRHADEARAFIHYLLSPKGQRILADANTGKYPVAPLS
                     ADNPRAAQQQRLMAQPPLNYRLILKRQQLVQRMFDTAISFRLAQLKDAWRALHSAETR
                     LKRPLPEIRALLTSVPVDAASSEDETWLAQFDNKSFAEQKMMEWQIWFLNNQRLAIHK
                     LEELK"
     gene            5424..7430
                     /gene="pgtB"
                     /locus_tag="OPY25_003810"
     CDS             5424..7430
                     /gene="pgtB"
                     /locus_tag="OPY25_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PgtB"
                     /protein_id="HCS0929308.1"
                     /translation="MKGRLLQRLRQLSISNSLRGAFLTGALLTLIVSMVSLYSWHEQS
                     SQVRYSLDEYFPRIHSAFLIEGNLNLAVDQLNEFLLAPNTTVRLQLRTQIIQHLDKIE
                     RLSQGLQLAERRQLAVILQDSRTLLAELDNALYNMFLVREKVSELSARIDWLHDDFTT
                     ELNSLVQDFTWQQGTLLDQIEANQGDAAQYLQRSREVQNEQQQVYTLARIENQIVDDL
                     RDRLNELKSGNNDGMLVETHIRYLENLKKTADENIRALDDWPSTITLRQTIDELLEIG
                     MVKNKMPDTMRDYVAAQKALLDASRAREATLGRFRTLLEAQLGSSHQQMQTFNQRLEQ
                     IVRVSGGLILVTTLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVY
                     GRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKEIEADLRAMQDELIQTAKLAVVGQ
                     TMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAEGLINRIDAIIRSLRQ
                     FTRRAELETPLYPVDLRQTFVAAWELLAMRHQSRQGALSLPTDTVWVSGDEVRIQQVL
                     VNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPGALLPSLLKPFTTSKAVG
                     LGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSVTDVDDVE"
     gene            7420..8667
                     /gene="pgtA"
                     /locus_tag="OPY25_003811"
     CDS             7420..8667
                     /gene="pgtA"
                     /locus_tag="OPY25_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PgtA"
                     /protein_id="HCS0929309.1"
                     /translation="MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEW
                     VKADWEGIVLSDVCMPGCSGIDLMTLFHQDDDQLPILLITGHGDVPMAVDAVKKGAWD
                     FLQKPVDPGKLLILIEDALRQRRSVIARRQYCQQTLQVDLIGRSEWMNQFRQRLQQLA
                     ETDIAVWFYGEHDTGRMTGARYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGT
                     LVLSYPEYLTREQQHHLARLQSLEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMT
                     QIACQSLSQRPDDIEPLFRHYLRKACLRLNHPVPEIAGELLKGIMRRAWPSNVRELAN
                     AAELFAVGVLPLAETVNPQLLLQEPTPLDRRVEEYERQIITEALNIHQGRINEVAEYL
                     QIPRKKLYLRMKKYGLSKEHYKF"
     gene            8935..9873
                     /gene="pgtE"
                     /locus_tag="OPY25_003812"
     CDS             8935..9873
                     /gene="pgtE"
                     /locus_tag="OPY25_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease PgtE"
                     /protein_id="HCS0929310.1"
                     /translation="MKKHAIAVMMIAVFSESVYAESTLFIPDVSPESVTTSLSVGVLN
                     GKSRELVYDTDTGRKLSQLDWKIKNVATLQGDLSWEPYSFMTLDARGWTSLASGSGHM
                     VDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFS
                     WTARGGSYIYDNGRYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSD
                     WVNAHDNDEHYMRKLTFREKTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGG
                     TQIIDKTSGNTAYFGGDAAGIANNNYTVTAGLQYRF"
     gene            10059..10205
                     /locus_tag="OPY25_003813"
     CDS             10059..10205
                     /locus_tag="OPY25_003813"
                     /inference="COORDINATES: protein motif:HMM:NF020812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929311.1"
                     /translation="MYSLWDCFNLWADIGNEKDRPGDYSLSEYPVHQLPTNHLVDGLV
                     AIGS"
     gene            10221..10364
                     /locus_tag="OPY25_003814"
     CDS             10221..10364
                     /locus_tag="OPY25_003814"
                     /inference="COORDINATES: protein motif:HMM:NF020812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929312.1"
                     /translation="MDGWGSYVSNILMQDCAGSGGLWYTYGKTFTYISVIDTKTLTLT
                     NCL"
BASE COUNT         2742 a         2460 c         2728 g         2681 t
ORIGIN      
        1 cattgtactt ttaaatcatc agggcgaaag taccggccca aacgatgacc ataaatgaaa
       61 tgcccataaa gaaatatttc acgtttcatc tctccgcgta cctgtcgtac gcctaaatga
      121 acttacactt acctgattat agagagttga tgccggataa tacgaaattg agaattattc
      181 gtgtttcgac cgcctgcatc acctcagaat tctgcgcgtc atcgctccag acggcgctaa
      241 tgtacgccta aaaatgaggt gaaacaagag gcattttctt atttattttt agtaacttac
      301 aagtgtcgtg aatcggcgac agtttaattt ctgacagtga tgaatcgcta ttgagcgacg
      361 ccgccgacac agtaaaaaaa cgcctgtaaa caggagactt atcgctaaaa gcaggaatga
      421 gtaatttacg atgtgaatat tatggcaatg cgaaatgaca aaataaaagg ccttgcggcc
      481 tttttcagat gtagagtgac gcttccccca acgggcgagt cttgaaacgg cgatgaatcc
      541 agagatattg ctccggggcg cgcatgatct ctttctcaat aattttattc atataggcag
      601 cggcttgatt ttcatctgcc gggtaacctt ccatttcagg ggtaatatac agacgataac
      661 ccgagttatc ggatttcctt accattgtaa cggtcagcat ggcggcgcca gacagcctgg
      721 acagtacata ggtaccgttg gtggtggcga cgttttcaac cgcgaaaaat ggcgcaaagg
      781 agctgccttt aggaccgtag tcctggtcgg gagcaaacca aacggcttcc ccttttttta
      841 gcgcgcccac aatgccgcgc agattgtttc tgccgatcat cgctttattt gagcgcatac
      901 gaccgcgcgt ctgcacccac tccatgagcg gattgttatg cggacgatag gtcgccatca
      961 tcggctggca gagacccatt acccggcctc ccaattccag cgacataaaa tgcacgccaa
     1021 cgaccattac gccgcgattt tgcgcctgcg cacgggtaag gttgtccagc ccgtccacat
     1081 caaaccattt gcgaacccgg ctatcaggcc agaaccaggc catgcccgtt tcaagcagcg
     1141 ccatgccaag agagtggaaa ttctcggcga tcagtttttc cctttcttcc cgggagaggg
     1201 tcggaaaaca gagttcaatg tttttctgag cgatcgactc acgtcgcttc aggaaggggc
     1261 gcgccagctt accggtgcgg gtgcccagaa aacgcaaaac cgggtaggga agctgcacca
     1321 gtaaccagag gacgccaacg ccaaaccacg tcagccagta gcgcgggtgc aaaaacgcgc
     1381 gtgaaaattt gctttgagga aacataaaat accttctgta gatacgaaaa taatgtatcg
     1441 cagaagagtc attatccgca gcggtacact ctgaaatacg catcatcctt caagttgcgt
     1501 tcgcttatcc gaagcactta cttgagtaag ctcatcaggg taacttgaat gatttgcgta
     1561 tagttaggcc atcatgtacg acaatggttc ccgtaaggag tgtaaaacta agtcagtact
     1621 aaaccacgag ggcatgaacg ccaggcaggc taatgtacca ccagttattt actcgcgccc
     1681 agaaattctt tatcaagaag cgtaaatatt tctcccgtag caaaaataag ctaatcatta
     1741 tttttaatgc attgttttta cagtgataat tttatttcag acgaaggtta ttgaaaaatg
     1801 attagaaaat aaaatgtgag ataaatgtta tggaaatgac gtgctgataa ggtttatctt
     1861 aaaggagaag tgagagggac cgtaaggcta tatggaagcc ttgccataga caggaggtat
     1921 tatagatgat ctatttatgg acatttcttg caataagtat acttgccgtg agtggctata
     1981 tcggtcaggt gatgggggct ttttctgcgg tttcttcttt tacgggaatg gttatccttg
     2041 ccgcgctgat ttatttactc aatgtatggc tgcaggatgg cgatgacatc gttagcggat
     2101 tattgctttt tctcgcaccg gcatgtgggt taattattcg ctttatggtg ggatacggta
     2161 agcgttagtc agtacatacc tttcatactt caagtggctt atgtgttggc tatggattac
     2221 tcggcccatt catgggcctc gccctgacgg gacgtcgctc accccagtca catcgttatc
     2281 tatgctcccg gggactcact cccttgccgc ttttaagcaa ctcgaattat ttttggtata
     2341 cacgatgtca gcgaatagat agcgccgaca atgtcggcgc ttctgttccc cgggaaggct
     2401 aatcgtttat tgcgcgtccg caagctgcag tgagtcctga ttatgtaacg cattctggcg
     2461 ctggcgttcc agttccagcg cgccgcgatg ggagaggtaa cagaatagaa tgcagcacac
     2521 gatgccgccc atcagaagat aaaatccgcc gtaccagccc agtttatcca ccatgacgcc
     2581 aaacaggctg gtgcccaacg aggcgccgaa aatatagctc atgaacccac gtaaaccgac
     2641 ggcggaacct acggcaaagc tggggactat ctccattgtc tgtacggacg cgaggaattg
     2701 cgggacgtaa atcagacaac ctacaatggc ggcgaaaatc gttaccatca gcaaagattc
     2761 acttttccag tatccgatca gacagacaaa aatcagcgcc atgcaaatca tggctaacgg
     2821 cattctgcgg cccttaaaca gtttatctga cagccagcct gccagtagcg tagagggaat
     2881 tgccgcccac tcgaaaaaga gaaacgcgac gctcatctgt tcttttgaaa agtgttttac
     2941 tgtcaacaga tagataggca accagctaat catgccaaac cgcaccatat agacgaagac
     3001 atcgaccagc gaaatatacc aggcattttt attgcgcagc acataagtac agaagatttg
     3061 ccatgcgctc atattttccg gcgcttttgc cgtattcttc gttttcagta tgactttttc
     3121 ttccggcatc atctgttcca gggagggaag accttcttcg cgcggcgaac cttttcccaa
     3181 gaccagaaca attaaggcaa aaatgacggc gacgcaggcc ggaacgatat aactggcgct
     3241 ttgccagtgt tcgctgccca atatcgcaaa agccgcaccg acgataggcg cgacgatccc
     3301 gccgccaacg ttatgcgaga tattccagaa ggcgcctacg cgtccgcgtt cccgacgagg
     3361 gaaccagttt gcaatagtaa taaacgaggg gccgacgccc atgccctgaa aaaggccatt
     3421 gaagaccacc agagcggcaa atatccagaa tgcgctactg aatcccagcc caacgttaac
     3481 aatcacgcag agtaccagac cgcacgccat gaagactttt gggctggctt tatccgccag
     3541 actgctcatt acgcctttac tgattccgta agcaataagc atacagctac tcagcaggcc
     3601 gatttgcgta gcgctgagat ccaattgctc ttttaaataa ggcgtcgata atgtgaagtt
     3661 gtttctgact atatagtaag cgagatatcc cagaaatacg cttaacaatg cctgtatacg
     3721 atatcgacca tacgtagcct ggactttttc cggtgggact ttatgcgccg atcgccctgt
     3781 ttttaatatt gttaacatgg agtcacctgt attttatagt gagatgaaca tcaggaggtt
     3841 ttgtcggtag agtgaaagga gtgacaataa aattcaagtc gaggaaatgt gtcaaaattg
     3901 actcaattgg gtgaatttaa aggttatttt tgacccatcc tgaagggtgt ggtgaaactt
     3961 taattattgg catggccgtt ttatcgttag catgtgcgga tattaacaaa tttgctgcca
     4021 gtgatctgat acgctttatt gatgttttcg ggcgacggac ccgttattat tcaaataacg
     4081 ttgttctgga tgccaacaga aataaaaggg taagttttgt ctcaatattt tctttatgtg
     4141 atatcgatat ttatgaacgg gatcacaaat cgacttttct catactgtgg ttgtttcgcc
     4201 agagtgggcg cttttacgct atggctggcg gcgatgttcg gttcttgcca ggcgtacagc
     4261 cgcgagctgg tgatggcaac gaccttttca cccagcgcga ccgcctggat tatccagcgc
     4321 tggcagacgg agccgggttc cgtcatgatt cgtacgctca accgtaccag cggttcttta
     4381 gagcaattac ttgatacggc gaatgcggaa aatgtcgatc tgatcctgac gtcatccccc
     4441 atgctgttgc aacaccttca ggagcaccaa aagctggcgc tattggatag cgcgcctgcc
     4501 gccagccaga agctggtgcc gcgttctatc cgctcaactt cagtggcggt agcggtatcc
     4561 ggatttgggc tattgatcaa ccgttcagcg ctcgctgcgc gccatcttcc gccgcctgcc
     4621 gactggcagg atatgggcct gcccagttac cagggcgctc tattaatgag cagtccgtca
     4681 cgctcagaca ccaatcattt gatggtggag tcgctgttgc agcaaaaagg ctggacggca
     4741 gggtgggcga cgctgctggc aatctcgggt aatttggtca cgatttcctc tcgcagtttc
     4801 ggcgtagcgg ataaaatcaa aagcgggctt ggcgttgccg ggccggtcat tgataactat
     4861 gctaatttgc tactcaacga tcctaatctt gcttttacct attttccgta ttctgcggtg
     4921 tcgcccactt acgtcgcggt gttgaaaaac agccgtcatg cagacgaagc gcgtgctttt
     4981 attcattact tattaagtcc gaaagggcaa aggatactgg ctgacgcgaa taccggtaag
     5041 tatcccgtcg caccgcttag cgccgataat cctcgcgccg cgcaacaaca gcgtttgatg
     5101 gcccagccgc cgttgaacta tcgtctgatc ctgaagcgtc agcaactggt acaacgcatg
     5161 tttgataccg cgatcagttt tcgtcttgcg cagcttaaag atgcatggcg agcgttgcac
     5221 agcgcagaaa cgcggcttaa acgcccctta cctgaaatca gagccttatt gaccagcgtc
     5281 ccggtggatg cggcaagcag cgaagatgaa acctggctgg cgcagtttga taataaaagc
     5341 tttgccgaac aaaaaatgat ggagtggcag atctggtttc tgaacaatca gcggctggcg
     5401 attcacaaac tggaagagct gaaatgaagg ggagattatt gcaacggctt cgtcagctca
     5461 gtatcagcaa cagtttacgg ggtgcatttt taacgggcgc attactgacg ctgattgtca
     5521 gtatggtcag cctttattcc tggcatgagc aaagttcgca ggttcgctat tcgcttgatg
     5581 aatattttcc tcgcatccac tccgcttttt taattgaggg gaacctgaat ctggccgtgg
     5641 atcaactcaa tgaatttttg ctggcgccga acacgacggt acgtttgcag ttacgtacgc
     5701 agattattca gcatctggat aagattgagc gtctcagtca ggggcttcag cttgctgagc
     5761 gccggcaact ggccgtcatt ttacaggata gccggacctt gctggcggag ctggacaacg
     5821 ccctctacaa catgtttttg gtgcgggaga aagttagtga gctttccgct cgcatcgact
     5881 ggctccatga tgatttcacc acggagctaa attcgctggt acaggatttt acctggcagc
     5941 aagggacgct gctcgatcaa attgaggcga atcagggcga cgcggctcag tacttgcaac
     6001 gttcgcgcga ggtgcagaac gagcagcagc aggtatatac cctggcgcga attgaaaatc
     6061 agattgttga tgacctgcgc gacagattga atgagctcaa gtccggcaat aatgacggga
     6121 tgctggtgga gacccatatt cgctatctgg aaaacctaaa aaaaacggcg gatgagaata
     6181 ttcgtgcgct cgatgactgg cccagtacga tcacgctgcg gcaaaccatc gacgaactat
     6241 tggaaatcgg gatggtaaaa aataagatgc ccgataccat gcgcgattat gttgcggcgc
     6301 aaaaagcctt actggacgcc agccgcgcca gagaggctac gctagggcgc tttcgcacgc
     6361 tgcttgaggc gcagttaggt agtagtcacc agcaaatgca gacgttcaat caacgcctgg
     6421 aacagattgt tcgcgttagc ggcgggctta ttttagtgac gacgctcctg gcgttgctac
     6481 tggcctgggg actcaaccac tattttatcc gttcccgact ggtgaagcgt tttaccgcgc
     6541 ttaatcaggc tgtggtacag atagggctgg ggagaaccga ctcgactatc ccggtttacg
     6601 ggcgcgatga gctaggacgg atagcccgct tgctacgtca tacgctgggc cagctcaata
     6661 tgcaacgcag gcagcttgaa caagaggtcg ccgagcgcaa agagatagaa gccgacctgc
     6721 gcgccatgca ggatgagttg attcagacgg cgaaactggc ggtagtcggc cagaccatga
     6781 ccacgctggc gcatgaaatt aaccagccgc tgaatgcgct ttcaatgtat ttatttacgg
     6841 cgggacgcgc gattgaacaa ggtcagagcg gacaggcgag aaatacgctc accaaagcgg
     6901 aagggctcat taaccggatt gacgccatta tccgttcgct gcggcagttt acccgtcggg
     6961 cggagctgga aacgccattg tatcccgttg atctgcgcca aaccttcgtg gcggcatggg
     7021 agttattagc catgcgccac caatcccggc agggagcgct ttcactgcca accgacaccg
     7081 tatgggttag cggcgatgaa gtgcgtattc agcaggttct ggtgaatgtg ctggcgaatg
     7141 cgcttgacgc ctgttcgcat gatgcggcga tcgcggtgac atggcagacg cagggagagg
     7201 cgctggaggt ttatattgca gataacggcc ctggctggcc tggggcgctg ttgccctctt
     7261 tactcaagcc gtttaccacc agtaaagctg tcgggttggg tattgggctg tcgattagcg
     7321 tgtcgctgat ggcgcaaatg aagggcgacc tgcgtctggc gtcgacgctg acgcgtaatg
     7381 cttgcgtggt gctgcaattc tcggtaacgg atgtcgatga tgttgaatga tgaatgttct
     7441 attttgctga ttgatgatga cgttgatgta cttgacgcct atacccaaat gcttgagcag
     7501 gcaggctacc gcgtgcgtgg ctttacccat cctttcgagg ccaaagagtg ggtaaaagcg
     7561 gattgggagg ggatcgtttt gagcgatgtg tgtatgccgg ggtgttccgg tatcgatctt
     7621 atgacgctgt ttcatcagga tgacgatcaa ctgccaatct tattgattac cggacatggc
     7681 gatgtaccga tggcggttga tgcggtgaaa aagggcgcct gggattttct gcaaaaaccc
     7741 gtcgatccgg gcaaactgtt gatattaatt gaagacgcgc tacgccagcg ccggtcggtt
     7801 attgcacggc ggcaatattg ccagcagacg ttacaggttg acctgattgg gcgcagcgag
     7861 tggatgaatc agtttcgaca acggttacaa caactggcgg aaacggacat tgccgtatgg
     7921 ttttacggtg agcatgacac aggacgtatg actggcgccc gttatctcca tcagctgggg
     7981 cgtaacgcga aagggccgtt tgttcgctat gaactcacgc cggagaatgc cgggcagttg
     8041 gagacattca tcgaccaggc gcaaggaggc acgctggtgt tgagttatcc cgaatatctg
     8101 acacgcgaac agcagcacca tctggcgcgt ttacaaagcc tggagcatcg gccttttcgt
     8161 ttggtgggcg ttggcagcgc ttcgctggtg gagcaggcgg cagctaacca gatagcggcc
     8221 gagctttact actgtttcgc catgacccaa atcgcctgcc agtctctttc tcagcgaccg
     8281 gatgatatcg agccgttatt tcgccattat cttcgaaaag cctgcctgcg actcaatcat
     8341 ccagtgccgg aaatagcggg ggaattactg aaaggaataa tgcgacgcgc ctggccaagc
     8401 aatgtgcgcg aactggccaa tgcggcggag ctttttgctg tcggcgtgct gccgctggcg
     8461 gaaacggtca acccgcagtt gcttctgcag gagccgaccc cgcttgaccg gcgcgttgaa
     8521 gagtatgagc gacaaattat taccgaagca ttaaatattc atcagggacg aattaatgaa
     8581 gtggcggagt acttgcaaat tccccgtaaa aaactttatc tgcgcatgaa aaaatatggt
     8641 ctaagtaaag agcattataa attctgatat tacagttact ttcaatctgg ctgacaacaa
     8701 cagcaacgat gtcgttagcc agataacgtc gcattaccgt aatggtaaat cattccatta
     8761 tgattataga ttgcttatta ttcacctgag catcaaattc tatttcttaa cttcaatata
     8821 aggtaaaaat gcgtcaagtt ctctggcgta ataaatgtac tcttgtccga cgatttgaca
     8881 agatgaaaac ttcatcacct ctccagatta catctgaata tgaggacaag agaaatgaaa
     8941 aaacatgcta ttgcagtaat gatgatcgcc gtattttctg agtcggttta tgcggagtct
     9001 accttattta ttccggacgt ctctcctgag agcgtcacga catccctttc tgtgggggtg
     9061 ttaaacggta aatccaggga gctggtttat gataccgaca ccggacggaa gctgagtcaa
     9121 ctggactgga aaataaaaaa tgtcgccacg ttgcaggggg atttatcatg ggaaccctat
     9181 tcgttcatga cgctggacgc ccgcggctgg acgtctttgg cgtcgggatc gggtcatatg
     9241 gttgaccatg actggatgag cagtgagcag ccaggctgga ccgatcgttc aattcatccg
     9301 gacaccagcg ccaactatgc taatgaatac gatttgaacg tgaaaggttg gttattgcag
     9361 ggagataact acaaggcggg cgtaacagcg ggctatcagg aaactcgttt tagctggacg
     9421 gcaagaggcg ggtcttatat ttatgataat ggtcgatata ttggtaactt tcctcatggc
     9481 gtgcgcggta taggttatag ccagcgtttc gaaatgccct atatcgggct ggcgggtgat
     9541 tatcgtatta atgactttga gtgtaatgta ctgtttaaat acagcgactg ggtaaatgcg
     9601 catgataatg acgaacacta catgcgaaaa cttaccttcc gtgaaaaaac ggaaaattca
     9661 cgatattatg gcgcgtctat tgacgccgga tattatatta ccagtaatgc aaaaatcttt
     9721 gctgagttcg cttacagtaa atatgaagaa ggtaagggcg gtacgcaaat catagataaa
     9781 accagcggta atacggcgta ttttggtggc gatgccgcag gtatagctaa taataactat
     9841 acggttaccg cggggttgca gtaccgcttc tagaccacat cgggatgtca tcggtcataa
     9901 ccggccgatg acgacttttt gctgaacgtg tggcatgccc ggtgatattg tgtttacctc
     9961 atatagatct ggcgagtttg gcgttaagac gtggcaagga acagtagagg gggacctcat
    10021 ccagatgtta taaacttcaa ttcagaaagt tactttccat atactctttg tgggactgct
    10081 tcaacctttg ggcagatatc ggaaatgaaa aagatagacc aggcgactat tcgctatcag
    10141 aatatccggt acaccaacta ccaacaaatc atttagtcga tggtctcgtt gccattggtt
    10201 catagagtgt tggtcttggt atggatggct ggggaagtta tgtatcgaac attcttatgc
    10261 aagattgcgc agggtctggt ggtctatggt acacatatgg gaagacattc acatatattt
    10321 ctgtaatcga tactaaaact ttaacactaa ctaattgttt gtagaaagtg gttgcattat
    10381 taatggtttg agactcattg acataaaaca aacaccatct ggtaatctgt cagaccccgc
    10441 atcctcaaca gttaactata aagattgtat ggtagctgag atgtcattag tcctaatatc
    10501 gtgtcagata aatttataaa agattactca tgttttgtgt cacatgcaaa aataattcgg
    10561 cttcgttaag gtctttaggg gaaataccta atggataatt agttagatta a
//
LOCUS       DAJVKX010000144        10595 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.144, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000144 DAJVKX010000000
VERSION     DAJVKX010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10595
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.144"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            118..339
                     /gene="ychH"
                     /locus_tag="OPY25_003815"
     CDS             118..339
                     /gene="ychH"
                     /locus_tag="OPY25_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HCS0929313.1"
                     /translation="MKRKNASLFGNVLMGLGLVVMVVGVGYSILNQLPQFNLPQFFAH
                     GAILSIFVGAVLWLAGARVGGHEQVSDKY"
     gene            complement(441..2126)
                     /gene="dauA"
                     /locus_tag="OPY25_003816"
     CDS             complement(441..2126)
                     /gene="dauA"
                     /locus_tag="OPY25_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HCS0929314.1"
                     /translation="MNKLFSSHVMPFRALIDACWKEKYTASRFTRDVIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTSAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLMSGFFLILFGLARLGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTVNIGDAAIGVVTLGTLIFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGNVATIGSQFHYVLADGTQGNGIPQLLPQLMLPWSLPGSDFTLSWDSLR
                     ALLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELIGQGLGNMVAPFFGGITATA
                     AIARSAANVRAGATSPVSAVIHAILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VNVDVPEDVLVLRVIGPLFFAAAEGLFTDLESRIKGKRIVVLKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRISNLEFQPLRTMARAGIKPIPGRLTFFPNRTEALADLLS"
     gene            complement(2251..3198)
                     /gene="prs"
                     /locus_tag="OPY25_003817"
     CDS             complement(2251..3198)
                     /gene="prs"
                     /locus_tag="OPY25_003817"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCS0929315.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LTDEIKALPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(3464..4315)
                     /gene="ispE"
                     /locus_tag="OPY25_003818"
     CDS             complement(3464..4315)
                     /gene="ispE"
                     /locus_tag="OPY25_003818"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCS0929316.1"
                     /translation="MMTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIE
                     PRHDGEIHLLTPVTGVENEDNLIVRAARLLMKVASESGRLPAGSGADISIEKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKR
                     FREVDAALSWLLEYAPSRLTGTGACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLS
                     PLHRELL"
     gene            complement(4312..4935)
                     /gene="lolB"
                     /locus_tag="OPY25_003819"
     CDS             complement(4312..4935)
                     /gene="lolB"
                     /locus_tag="OPY25_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HCS0929317.1"
                     /translation="MTLPDFRLIRLLPLASLVLTACTLPGHKGPGKSPDSPQWRQHQQ
                     EVRHLNQYQTRGAFAYISDDQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEV
                     NYHQDGKNWKVVYGGYDSKTQPAMPANMELSDGSQRIKLKMDNWIVK"
     gene            5249..6505
                     /gene="hemA"
                     /locus_tag="OPY25_003820"
     CDS             5249..6505
                     /gene="hemA"
                     /locus_tag="OPY25_003820"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HCS0929318.1"
                     /translation="MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQALADEVGAEVISLSDIDARLQDADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVEAETIVEQEASEFMA
                     WLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAP
                     TKSLQQAARDGDDERLNILRDSLGLE"
     gene            6546..7628
                     /gene="prfA"
                     /locus_tag="OPY25_003821"
     CDS             6546..7628
                     /gene="prfA"
                     /locus_tag="OPY25_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCS0929319.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAGIIADQDRFRALSREYAQ
                     LSDVSRCFTDWQQVQDDIETAQMMLDDPEMREMAQEELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSMSEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPEAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAETAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDETME
                     GKLDMLIEPIVQEHQADLLAALSEQE"
     gene            7628..8461
                     /gene="prmC"
                     /locus_tag="OPY25_003822"
     CDS             7628..8461
                     /gene="prmC"
                     /locus_tag="OPY25_003822"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCS0929320.1"
                     /translation="MDFQHWLHEAVNQLRDSDSPRRDAEILLEYVTGKRRTYIMAFGE
                     TPLTDVQQQQLAELLQRRKQGEPIAYLTGLREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPVKTCRILDLGTGTGAIALALACERPDCEVTAVDRMPDAVALAIRNAEHLAIRN
                     VRILQSCWFSALSGQQFDMIVSNPPYIDAQDPHLSEGDVRFEPRSALVADENGMADLT
                     HIIDNARQMLTPGGFLLLEHGWRQGEAVRAAFRRSGYTDVETCRDYGGNERVACGRFT
                     P"
     gene            8458..8847
                     /locus_tag="OPY25_003823"
     CDS             8458..8847
                     /locus_tag="OPY25_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HCS0929321.1"
                     /translation="MTIAMLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVP
                     PVIDTLLLLSGIGLIVKTHILPFTESGSWLTEKLFGVIIYIVLGFIALDYRQARSQQA
                     RFIAFPLALVVLYIIIKLATTKIPLLG"
     gene            8851..9660
                     /locus_tag="OPY25_003824"
     CDS             8851..9660
                     /locus_tag="OPY25_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HCS0929322.1"
                     /translation="MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSL
                     AQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYRLSDALWLDKVLKKRQGSAVSLG
                     AILLWIANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
                     SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEI
                     RDRGLIYAQLECEHVALTDLSYFVEQCPEDPISEMIRAQINTIAHKQIVLH"
     gene            9698..10552
                     /gene="kdsA"
                     /locus_tag="OPY25_003825"
     CDS             9698..10552
                     /gene="kdsA"
                     /locus_tag="OPY25_003825"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HCS0929323.1"
                     /translation="MKQKVVNIGDIKVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGN
                     DKVILCDRGANFGYDNLVVDMLGFSVMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     GQVTELARAGMAVGLAGLFLESHPDPANAKCDGPSALPLAKLEQFLTQIKAIDDLVKS
                     FDELDTEN"
BASE COUNT         2488 a         2798 c         2998 g         2311 t
ORIGIN      
        1 atgaaacttt acatttgtga tcgcacccgc acttacaaat ggaagtgttg tctatacttt
       61 acacataaag tttaggggga tttcctaaaa acaacccaaa agttccggag gtgacatatg
      121 aaacgcaaaa acgcttcgtt attcggtaac gtgctgatgg ggttggggct ggtcgtgatg
      181 gttgtcggcg tgggttactc tattttaaac caactgccgc agtttaattt gccgcaattt
      241 tttgcgcatg gcgcaatact gagcattttt gtcggtgcag ttctttggct ggcgggggct
      301 cgtgtagggg ggcatgagca ggtgagcgac aaatattagt gggtacgtca ctatgacaaa
      361 cgttgccgcc gtagcgacaa tcgtcgtcat agctaaccgg ttcaggcccg gtaagcgtta
      421 tcgccaccgg gcattgtcca ttaactgagt aaatccgcta acgcctccgt cctgttcggg
      481 aagaaggtca gacgtccagg aatgggtttg ataccggcac gcgccattgt gcgcagcggt
      541 tggaactcca ggttactgat acgcaattcg caaccctccg gcagacgctt cacaaaacgc
      601 tgaaaagcat caagcccgcc tgcatccagc actggtactg cgtcccattt cagaacgacg
      661 atacgtttgc ccttaatacg tgactcaagg tcggtaaaca gcccttccgc cgcggcgaaa
      721 aagagcggac cgataacacg cagcaccagc acatcttcag gcacatcgac attgaccggc
      781 gcaagtcgag tcattcgcgc aatacggcgc ataaacagca gggaagcaag gacaatcccc
      841 acgctgatgg cgatgaccat atcaaacaga accgttaatg acatgcacag cagcataacg
      901 ataatgtcat ctttcggcgc atggcgtaac agatccacca ctttatgggc ttcactcata
      961 ttccatgcca ccatcagcag tagcgccgcc atcgcggaaa gcggcagcca ggagagtagc
     1021 ggggctaaga ccagtagcgc cagaatgacc agaatagcgt gaattaccgc cgagacggga
     1081 gaggtcgcgc cagcgcggac gttggcggca gagcgggcaa tcgcggcggt ggcggtgatg
     1141 ccgccaaaga acggcgcgac catattcccc agcccctggc cgataagttc gctgttagct
     1201 ttatgtttgg tgccggtcat gccgtccagc acgacggcgc agagcaatga ttcgattgcc
     1261 cccagcattg ccatcgagaa agccgctggc agcagcgcgc gcagtgaatc ccagcttagc
     1321 gtaaaatcgg agccaggaag gctccacggc agcatcagtt gcggcaggag ctgcgggatg
     1381 ccgttgccct gagtgccgtc agccagaacg taatggaact gtgagccgat agtcgccaca
     1441 ttgccgccca gcagattaac aatccccatt acggcgcaac cggccagcag cgcgggaagg
     1501 tgtcccggca gacgaatacc gagacgcggc cagaaaatca gcgttcccag cgttaccacg
     1561 ccaatggcgg catcgccaat attgacggtg ggcaacgcca taaacagcgc gccgactttc
     1621 tgcaaatagt gctctggcac atgggccatc tgcagaccaa gaaaatcttt aatctgcatg
     1681 gtaccgatgg taataccaat ccctgaggta aaacccaacg tgaccgacac cgggatatat
     1741 tcaatcaatc gccccagtct cgccaggccg aaaaggatca ggaagaagcc cgacatcagc
     1801 gtggcgacca gtaggcccgc cagaccaaac tgttgcgaca ccggatacaa aatcaccaca
     1861 aacgcggcgg tagggccgga aacgctaaag cgcgagccgc cggttagcgc gatcacgatc
     1921 ccggcgacag cggaggtata gaggccatac tgcggcgcaa cgccactgcc aattgccagc
     1981 gccatcgcca gcgggatagc aataatcccg acggtgatcc cggctatcac atcacgggtg
     2041 aaccgggagg cggtatattt ttctttccag caagcatcga tgagagcgcg gaaaggcatc
     2101 acatgtgagg aaaataattt gttcacaata atgtttcatc catgagcgca tcatctgtca
     2161 actaaatggc aggtgaagga ggcataagtc atataaaagg gtgttacaga caaaaaaacc
     2221 cgccgcagcg ggtttcagat ccgggttcga tcaatgctcg aacatggcgg aaatcgattc
     2281 ttcgttgctg atacggcgaa tcgcttcggc cagcatacct gacagggtca aagtacgcac
     2341 gttcggcagc gctttgattt cgtcggtcag cggaatggtg tcacagacaa cgacttcgtc
     2401 aataacggag ttgcgcaggt tgtttgccgc attgcctgag aagatcgggt gcgtcgcgta
     2461 ggcaaacacg cgtttagcgc cacgttcttt caatgcttct gctgctttgc acagagtacc
     2521 gccggtatcg atcatatcat caaccagcac gcagtcacgg ccagcgacgt cgccgatgat
     2581 gtgcatcacc tgagaaacgt tcgcgcgcgg acgacgttta tcaatgatag ccatatcggt
     2641 atcgttcagc agcttagcga tagcgcgggc acgaaccacg ccgccaatat ccggggaaac
     2701 cacgattggg ttatccagat tcagttgcag catatcttcg agcaggattg ggctaccgaa
     2761 cacgttatca accggaacgt caaagaagcc ctggatctgt tcagcatgca gatctacggt
     2821 gagaacgcgg tcaacgccga cgctggacag gaagtcagcg acaacttttg cggtaatcgg
     2881 cacacgggcg gaacgtacgc gacggtcctg acgtgcatag ccaaagtagg ggataacggc
     2941 ggtgatacga cctgcggaag cacgacgcag ggcatcaacc ataacgacca attccatcag
     3001 gttgtcgttg gttggggcac aagtggactg gatgatgaaa atatcaccac cgcgtacatt
     3061 ttcgttgatt tgtacgctga cttcgccgtc gctaaagcga cctacggcgg cgtcgccgag
     3121 agaagtgtac aggcggttgg caatacgttg tgctagttcc ggggtggcgt taccagcaaa
     3181 aagcttcata tcaggcacga gaagaacctc aggcatgcgt ccattggtgg aaagaatctg
     3241 ccgaaaactg tgcgggccag gcaaaatcct atccaggcgg tgtattaaag agcgcgatgc
     3301 aacgtctgga acaaggtgac gttgtcaccg aagctcagct tgcccggctt actcgtcttc
     3361 attcacgttt catgtgcgct ggtatcaatg cctcacaccg gtcaaatacg gcatatatga
     3421 ccggcgactc gtcatttcgc catcttcctg aaacccgaat gcgttagagt aactctcgat
     3481 gcaatgggga aaggttaaca cccttcgcca caaaagcatt gagccattcc ggggcttgct
     3541 caagcacctg gcgagcacaa gactctgtat cgaattcagc aaagacacag gcccctgtcc
     3601 cagtcaggcg cgacggcgcg tattctaaca gccaggaaag cgccgcatca acctcgcgaa
     3661 aacgttttct tgcgataacc tcgcaatcat tgctgaattc acattttagt aacgtatcta
     3721 ttgacctttt tggcgtatta cgcggcaatt gaggatcttt aaagataact ggcgtcggaa
     3781 tgcttacgcc agggtgcgcg accagatacc atttttccgg cggattcacc ggcgttaata
     3841 tttcgcctac gccttcggca aacgcggcgt ggccacgaac aaagaccggg acgtcggcgc
     3901 cgagcgtcag gccgagcgtc gccagttcat caatggaaag cccgcattgc caaagatgat
     3961 tgagcgccac cagaacggtc gcggcgttag acgagccgcc acccagaccg ccgcccatgg
     4021 gaaggcgctt ctcaatgctg atatccgcgc cgcttccggc gggcaggcgt ccactctccg
     4081 aggcgacttt catcaacagc cgcgcggcgc ggacgatcag attgtcttca ttttcaacgc
     4141 cggttaccgg cgttaataaa tggatttcgc catcgtgacg cggttcgatg tggagtgtgt
     4201 cgccataatc cagaaactga aacagcgtct gcagcgtgtg gtagccgtct gcacgctgtc
     4261 cggtgatata taaaaacaga tttaattttg ccggagaagg ccaatgggtc atcatttcac
     4321 aatccagtta tccattttca gcttaatgcg ctgactgcca tctgaaagct ccatattggc
     4381 tggcatggca ggctgcgttt tgctgtcata gccaccgtaa accactttcc agtttttacc
     4441 atcctggtgg tagttcactt cgctcaggcg gtactggtcg tccagtttgt agtcggtggc
     4501 atcgccaggc agaccgagga tccactgccg caggctgttt aacggaatcg gcatcccggt
     4561 gagtttgccg atcatctctt cggcgtcatc ggcggtataa cgctggcctt tgttatccac
     4621 caactggacg ttgcccggct gggcgttaag ctccagctcg gtgctgccca gcgggttggt
     4681 aagcagcagg cggtagcgat cctgtccggt ctgttgccag aagaagcgcg catagacttt
     4741 ctgatcatct gagatgtaag caaaggcgcc gcgcgtctgg tattgattca gatgacgcac
     4801 ctcttgctga tgctggcgcc actgagggga atccgggctc ttgcccgggc ctttatgccc
     4861 aggaagcgta caggcggtga gaaccaggct tgctaacggc agtagacgaa tcaggcgaaa
     4921 atcgggcagg gtcatagtga tgacgaatcc ttgtgatacg gtgcaataat tgcctgaagg
     4981 cgttacgctt atcaggcctg aaaactgaac cggcaagctg taaaaacgtt cgcgccgcga
     5041 ttcggcaaat ttttgctatc ggttacagtt atagccttta atgctagcgc cgcctggtga
     5101 catcgtctac tttcaagttg tcttaaatca tcaaattagc gagcgctgcc aattactcca
     5161 aaagggggct ctctctttta ttgaccacgc gcatcctgta tgatgcaagc agactaacca
     5221 tatcaacgct ggtactactc ccgcagacat gaccctttta gcactcggta ttaaccataa
     5281 aacggcacct gtatcgctgc gagaacgcgt aacgttttcg ccggacacgc ttgatcaggc
     5341 gctggacagc ctgcttgcgc agccaatggt gcagggcggg gtcgtgctgt caacctgtaa
     5401 ccgtacagag ctgtatttga gcgtggaaga gcaggataac ctgcaagaag cgctgatccg
     5461 ctggttatgc gattaccata acctgaacga ggacgatctg cgcaacagtc tgtactggca
     5521 tcaggacaat gacgccgtca gccacctgat gcgcgtcgcc agcggtctgg attcactggt
     5581 gctgggcgaa ccgcaaatcc tcggtcaggt gaaaaaagcg tttgcggatt cgcaaaaagg
     5641 ccaccttaac gccagcgcgc tggagcgaat gtttcagaag tctttttccg tcgccaagcg
     5701 agtgcggact gaaaccgata tcggcgccag cgccgtctcc gtcgcgtttg ccgcctgtac
     5761 gctcgcccgc caaatctttg aatcgctctc gacggtcact gtactgttag ttggcgcggg
     5821 cgaaactatt gaactggtgg cgcgtcacct gcgcgagcat aaagtacaaa agatgattat
     5881 cgccaaccga acccgcgagc gcgcgcaagc cctggcggat gaggttggcg ctgaggttat
     5941 ctcgctcagc gatatcgacg cccgcttgca ggatgccgat attatcatca gttcgaccgc
     6001 cagcccgctg ccgattatcg gtaaaggcat ggtggagcgc gcattaaaaa gccgtcgcaa
     6061 ccagccgatg ctgctggtgg atatcgccgt accgcgcgac gttgagccgg aagtcggcaa
     6121 actggcgaac gcttatcttt atagcgtcga tgatttacag agcatcattt cgcataatct
     6181 ggcgcagcgt caggctgcgg cggtggaagc ggaaacgatt gttgagcagg aagccagcga
     6241 gtttatggcc tggctacgcg cccagggggc cagcgagacc attcgggaat accgtagtca
     6301 gtcggagcag attcgtgacg aactgactac caaagcgctg tcggcccttc aacagggcgg
     6361 tgatgcgcaa gccatcttgc aggatctggc atggaaactg accaaccgcc tgattcatgc
     6421 gccaacgaaa tcacttcaac aggctgcccg tgacggggat gacgaacgcc tgaatattct
     6481 gcgcgacagc ctcgggctgg agtagcagca cacaccacac ttttttacag ggtgaattta
     6541 cgcctatgaa gccttctatc gttgccaaac tggaagccct gcacgaacgc catgaggaag
     6601 ttcaggcgtt gctgggcgat gcgggaatta tcgccgacca ggaccgcttt cgcgcattgt
     6661 cgcgcgaata tgcgcaatta agcgacgttt ctcgctgttt tacggactgg caacaggttc
     6721 aggacgatat cgagacggct cagatgatgc tcgacgatcc tgaaatgcgg gaaatggcgc
     6781 aggaagaact gcgcgaagcg aaagaaaaaa gcgaacaact ggagcaacag ttacaggtac
     6841 tgctgctgcc gaaagatccg gacgatgaac gaaacgcgtt ccttgaggtt cgcgccggca
     6901 ctggcggcga cgaagccgcg ctgtttgccg gcgatctgtt ccgcatgtac agccgttatg
     6961 ccgaagcgcg ccgctggcgc gtggagatca tgagcatgag cgaaggcgag catggcggtt
     7021 ataaagagat catcgccaaa atcagcggcg acggcgtgta tggccgactg aaatttgagt
     7081 ccggcggaca ccgcgtacag cgtgttccgg cgaccgagtc gcaggggcgt atccatacct
     7141 ccgcctgtac cgtcgccgtg atgccggagc tgccggaagc cgagctgccg gatattaacc
     7201 cggcggatct gcgcattgat acgtttcgtt cttccggcgc gggcggtcag cacgttaaca
     7261 ccaccgactc cgctatccgt attacccact tgccgaccgg catcgtggtg gaatgccagg
     7321 acgagcgttc gcagcataaa aacaaagcga aagcgctctc ggtgctcggg gcgcgcattc
     7381 acgccgccga aacggcaaaa cgccagcagg ccgaggcgtc aacgcgccgc aacctgcttg
     7441 gcagcggcga tcgcagcgat cgtaaccgga cctataattt cccgcagggg cgcgtgaccg
     7501 atcatcgtat taatctgacg ttatatcgcc ttgatgaaac gatggaaggt aagctggata
     7561 tgctgattga gccgattgtt caggaacacc aggctgacct gttagccgcg ttgtccgagc
     7621 aggaataatg gattttcagc actggctaca tgaggcggta aaccagctcc gggacagcga
     7681 cagcccccgg cgcgacgccg agatcctgct tgagtacgtt acgggcaaga ggcggacgta
     7741 tatcatggcc tttggcgaaa cgccgcttac cgatgtccag caacaacagc tcgcggagct
     7801 gctgcagcgg cgtaaacagg gcgaacccat tgcgtacctg acgggcttac gcgaattttg
     7861 gtcgctgccg ctcttcgttt ctcccgccac gctaatcccg cgcccggata ccgaatgtct
     7921 ggttgaacag gcgttggcgc gattgccggt caaaacctgt cgtattctgg atttaggcac
     7981 cggaaccggc gcgattgcgc tggcgctggc ctgcgagcga ccggattgcg aggtgactgc
     8041 ggtcgatcgt atgcctgatg cggttgcgct ggcgatacgc aacgcggaac atttggctat
     8101 ccggaatgtg cgtatactgc aaagttgttg gttcagcgca ctatcggggc agcagttcga
     8161 catgattgtc agcaatccgc cctacattga cgcgcaggac ccgcacctta gcgaaggcga
     8221 tgtacgcttt gaaccgcgct cagcgttggt ggcggacgaa aacggtatgg cggatcttac
     8281 gcatattatc gataatgccc gccagatgtt aacgcccggc ggcttcctgc tgctggaaca
     8341 cggttggcgg cagggcgaag cggtaagagc ggctttcagg cggtctggtt acacggatgt
     8401 agaaacgtgt cgtgattatg gtggcaatga acgcgtggcc tgcgggcgtt ttacgccatg
     8461 acaattgcaa tgttgctcac gcttcatctt atttgtgttg cgctctccgt cagtttgttt
     8521 gtcgctcgtt actggtggcg ctattgcggc catgcgttgg ccgccgcgcg ctggacacga
     8581 atcgtgcctc ccgtcataga taccctgtta ctgcttagcg gtattgggtt aatcgttaaa
     8641 acgcacatcc tgccattcac ggagtcgggc tcatggctga ctgaaaaact gtttggcgtt
     8701 atcatctaca tcgttttggg ttttattgcg cttgattatc gtcaggcgcg cagccagcag
     8761 gcgcgtttta tcgctttccc gctggcgctg gtggtgctgt acatcatcat taaactcgcc
     8821 accacaaaaa taccgttact ggggtaagtc atgaggtcgt tagctgattt cgaatttaac
     8881 aatgcgccgc tgtgtgatgg catgatcctg gcatcagaga tgattcgcct ggattttccc
     8941 acgcagtttg tctacgacga actggaacgt ctggtcagtc tggcgcagga agaaattagc
     9001 cagctcctgt ctcaggatga gcaactggaa aaattgctgg cactttttta cggcgagtgg
     9061 gggttcacgg attcccgcgg cgtctaccgt ctttctgatg ctttatggct cgataaagtc
     9121 ctgaaaaaac gccaggggag cgctgtatcg ttgggcgcta ttttattatg gatagcaaac
     9181 cgtcttgatt tgccgttggt gcccgttatc ttcccaacgc agctgatttt gcgtattgaa
     9241 tcgctggaag gagaaatgtg gctgattaac ccgttcaacg gtgaaacgct tgatgaacat
     9301 accctcgaag tctggttaaa aggcaatatt agtccggtcg ccgagttgtt taacgaagat
     9361 ttggacgaag cggataacgc cgaagtgatt cgtaagctac tggatacgct gaaatcctcg
     9421 ctgatggagg aacggcaaat ggagctggcg ctgcgcgtta gcgaagcatt gttgcaattt
     9481 aacccggaag atccttacga aatccgtgac cgcgggttga tctacgcgca gcttgagtgt
     9541 gaacacgttg cgctgactga tttaagctac ttcgttgaac agtgtccgga agacccgatc
     9601 agcgaaatga ttcgtgcgca gatcaacacc attgcgcaca agcaaattgt tctacattaa
     9661 ttaaccgaca ttttacctat aagtgtaagg cgatcctatg aaacaaaaag tggttaacat
     9721 tggcgacatt aaggtggcaa atgacctgcc gtttgtgctg tttggcggta tgaacgtgct
     9781 ggagtcacgc gatctggcaa tgcgcatttg tgagcactac gtaaccgtta cccagaagct
     9841 gggtattcct tacgtgttca aggcctcttt tgataaagcc aaccgttcct ctattcactc
     9901 ttaccgtggg ccgggtctgg aagaagggat gaaaatcttc caggaactca aacagacatt
     9961 tggcgtaaaa gtgatcactg acgtccatga agccagccag gcgcagcctg tggctgatgt
    10021 ggttgacgtg attcagctcc cggcgttttt ggcgcgccag accgacctgg tggaagcgat
    10081 ggcgaaaacc ggcgctgtga ttaacgtgaa aaagccgcag tttgtaagcc cgggtcagat
    10141 gggcaatatc gtggataagt tccatgaggg cggtaacgat aaggtgattc tgtgcgatcg
    10201 cggcgcgaac ttcggttatg acaacctggt ggtggatatg ctgggcttta gcgtgatgaa
    10261 aaaggtctcc ggcaactcgc cggtgatttt cgacgttacc catgcgctgc aatgccgcga
    10321 cccatttggc gctgcctcgg gcggtcgtcg tggtcaggtg accgagctgg cgcgcgccgg
    10381 tatggctgtc ggtctggcgg gcctgttcct ggagtcgcat ccggacccgg ctaacgcgaa
    10441 gtgcgacggt ccttccgcgc tgccgctggc gaaactggag cagttcctga cccagataaa
    10501 agcgattgat gatttggtga aaagcttcga cgagctggat accgagaact gattgcggtt
    10561 tttagcttgt gtaggccgga taagatacta tccgg
//
LOCUS       DAJVKX010000145        10289 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.145, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000145 DAJVKX010000000
VERSION     DAJVKX010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10289
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.145"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..878)
                     /gene="nadK"
                     /locus_tag="OPY25_003826"
     CDS             complement(<1..878)
                     /gene="nadK"
                     /locus_tag="OPY25_003826"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HCS0929324.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIA
                     HELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLT
                     DLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            1002..1592
                     /gene="grpE"
                     /locus_tag="OPY25_003827"
     CDS             1002..1592
                     /gene="grpE"
                     /locus_tag="OPY25_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCS0929325.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEVEAVEPNDSAEQVDPRDEKI
                     ANLEVQLAEAQTRERDTVLRIKAEMENLRRRTEQDIEKAHKFALEKFVNELLPVIDSL
                     DRALEVADKANPDMAAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESEEVPAGNVLGIMQKGYTLNGRTIRAAMVTVAKAK"
     gene            complement(1674..2231)
                     /locus_tag="OPY25_003828"
     CDS             complement(1674..2231)
                     /locus_tag="OPY25_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001688360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0929326.1"
                     /translation="MSEDYVIEWDKNFADDLNVVANVFLSHNPTLWPTIFSQLSTQPE
                     IFEDEDEDEYGLQDVLDCSGGDLGNNELAQAFLQVLRGEGFIHLVDWKGEDEEGELAN
                     FAADRFYELTKNLTDSEELRNLLVEITQEDEISDVCEAGDRYLDEIFERIQTELNKRG
                     FQIFDLNEGSDTYNVVVLPMSEYKK"
     gene            complement(2352..3638)
                     /locus_tag="OPY25_003829"
     CDS             complement(2352..3638)
                     /locus_tag="OPY25_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCS0929327.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNTITRLLMRLMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKVSVDDIMVPRNEIIGID
                     INDDWKSIERQLTHSPHGRIVLYRDSLDDAISMLRVREAWRLMAEKKEFTKEMMLRAA
                     DEIYYVPEGTPLSTQLIKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIEQYDIDILDVQENMIKQVKVVPVKPLRESVAE"
     gene            complement(3658..4449)
                     /locus_tag="OPY25_003830"
     CDS             complement(3658..4449)
                     /locus_tag="OPY25_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HCS0929328.1"
                     /translation="MPVFALLALVAYSFSLALIVPGLLQKNSGWRRMAILSAVIALVC
                     HAVALESRILPGGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLAFATFMPNEYITHLEATPGMMVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFSNEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSTENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAGILTLAYFGSRILQQFVS"
     gene            4615..5976
                     /gene="ffh"
                     /locus_tag="OPY25_003831"
     CDS             4615..5976
                     /gene="ffh"
                     /locus_tag="OPY25_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCS0929329.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKETLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRSELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASIKPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTDALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLATKLKKGDGFDLNDF
                     LEQLKQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTLKERAKPE
                     IIKGSRKRRIAQGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            6320..6568
                     /gene="rpsP"
                     /locus_tag="OPY25_003832"
     CDS             6320..6568
                     /gene="rpsP"
                     /locus_tag="OPY25_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCS0929330.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVTDSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVKKAA"
     gene            6587..7135
                     /gene="rimM"
                     /locus_tag="OPY25_003833"
     CDS             6587..7135
                     /gene="rimM"
                     /locus_tag="OPY25_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCS0929331.1"
                     /translation="MSKQLAAQVPAEPVVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDLIIKLKGVDDRDAANLLTNCEIVVDSSQLPALE
                     EGDYYWKDLMGCQVVTAEGYDLGKVIDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLATRTIEVDWDPGF"
     gene            7180..7947
                     /gene="trmD"
                     /locus_tag="OPY25_003834"
     CDS             7180..7947
                     /gene="trmD"
                     /locus_tag="OPY25_003834"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCS0929332.1"
                     /translation="MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFAHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGVDERVIQAEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVL
                     GHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            7988..8335
                     /gene="rplS"
                     /locus_tag="OPY25_003835"
     CDS             7988..8335
                     /gene="rplS"
                     /locus_tag="OPY25_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCS0929333.1"
                     /translation="MSNIIKQLEQEQMKQNVPSFRPGDTVEVKVWVVEGTKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSIAVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(8492..9712)
                     /gene="dgcN"
                     /locus_tag="OPY25_003836"
     CDS             complement(8492..9712)
                     /gene="dgcN"
                     /locus_tag="OPY25_003836"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HCS0929334.1"
                     /translation="MNKEFSLSRPTFKRTLRRISIISVLLTMTLIWLLICVASVLTLK
                     QYAQKNLDLTAATMAHSLEAALVFSDSAAAAETLATLGRQGQFSAAEVRDKNGRTIAS
                     WRYDARAADDKLIGLISHWLFPLPVSQPVWHNGRAIGEVRLVARDSLIGHFIWLSLAV
                     LTGCILLASGIALLLTRYLHNGVVDALQNITEIVHDVRTNRNFSRRVPDERIAEFHLF
                     AQDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSCINALMKDNSARS
                     SSALLFLDGDNFKYINDTWGHAAGDRVLIEVAKRLAEFGGSRYQTYRLGGDEFAMVLY
                     GVHSEYEVQRICAALSQAFNRPFELHNGQRITMTLSIGFALTWEHATAEKLQELADRN
                     MYQAKHRRAERSLN"
     gene            complement(9705..10223)
                     /locus_tag="OPY25_003837"
     CDS             complement(9705..10223)
                     /locus_tag="OPY25_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HCS0929335.1"
                     /translation="MRFSHRFILLLSLLLASLPLYAQCVTEEEKSVRAIVSGIVSYTH
                     WPALSGPPRLCIFSSARFVRVLSEEANWAFPYQPLVIRTTQEALSARCDGFYFGNESP
                     AYQVELTRHYPVNALLLIAEQNTECIIGSAFCLIINNDEVKFSVNLDSLSHSGVRVNP
                     EVLMLARNQKHE"
BASE COUNT         2633 a         2506 c         2722 g         2428 t
ORIGIN      
        1 tagaataatt tttttgacca gccgagtttt gtgcttaatg tattgaaata gctatagtct
       61 ttgggatgta tcaggttgag atggtagtcg cagcggcgaa tcagcacatc ttctccttcc
      121 tgaataggca gcgctatctg actgtcgcag ctaatttcca gatcgctacg gcgatgcgaa
      181 aaacgcagac gaatcgtgct actgctgtta atgactaacg ggcgcgccga caaggtatgc
      241 gggaacatcg gcaccagggt gatggcatcc agtgaagggg tcagaatagg gccgcctgcg
      301 gagagcgaat aggcggtgga gccggtcggc gtagaaatga tcagaccatc agatcgctgt
      361 gaaaaagcga aggtttcatc aatataaacc tcgaattcga tcatatgcgc cacttttccc
      421 ggatgcagca ccacttcatt aatggctgtg ctgatacgct tctggcggtc ctgttggcag
      481 acctgcgctt ccagcagaaa acgtttttcg gagatatagc gtccttccag cacatccgat
      541 aattgttgca gggcgttgtc cggatcgaga tcggtcagga agccaagatt accgcggtta
      601 atgccaatca cattgatgtc ataacgcgcc agcgtacgcg ctgcgccaag catattgccg
      661 tcgccgccca caactaccgc cagatccgcc tgttgaccaa tttccgccag cgtgccggtt
      721 ggcacatttt ttagctgtaa ttcgtgggcg atttgttgct ccacaatgac ctcataaccc
      781 tgatcgcata gccaacggta gagcatttca tgtgtcgtga gtgcggtggg atgacgcgga
      841 tgccccacaa tgccgataca cttgaaatga ttattcattt ttctgaggtc cttgtagcga
      901 agattgatga caatgtgagt acttcccttg aaaccctgaa tctgatcccc ataataagcg
      961 aagttagcga gatgaatgcg aaaaaaaacg cggagaaatt catgagtagt aaagaacaga
     1021 aaacgcctga ggggcaagcc ccggaagaaa ttatcatgga tcagcacgaa gaggttgagg
     1081 cagttgaacc aaacgattct gctgagcagg tggatccgcg cgatgaaaaa attgcgaatc
     1141 tggaagttca gcttgccgaa gcccagactc gcgaacgcga caccgtgttg cgtatcaaag
     1201 cggaaatgga aaacctgcgc cgccgtactg aacaggatat cgaaaaagcg cataaattcg
     1261 ctctcgagaa gttcgtcaac gaattgctgc cggtaatcga tagcctggat cgcgcgctgg
     1321 aagtcgcaga caaagccaat ccggatatgg cggcaatggt cgaagggatt gagctgacgc
     1381 tgaagtctat gctggatgtg gtgcgtaagt tcggcgtgga agtgattgct gagaccaacg
     1441 tgccgctgga cccgaacgtg catcaggcga ttgcgatggt ggaatcggaa gaggttccgg
     1501 caggcaatgt gctgggtatt atgcagaaag gctacacgct gaacggtcgt accattcgcg
     1561 cggcgatggt gactgtagcg aaggcgaagt aaaagtctaa tggccgatgt aaagtcggcc
     1621 atttttttag cttaaaaaat cctgcacttc cagccacggc gtgttgaaat cctctatttt
     1681 ttatattcgc tcattggcag aacgaccaca ttataggtgt cagatccttc attcagatca
     1741 aaaatctgga agcccctctt attgagttcg gtctggatgc gttcaaagat ctcgtcaagg
     1801 taacggtccc cggcttcaca gacatcggag atttcatcct cttgggttat ttcgacaaga
     1861 agatttctta attcctcaga atccgtcagg ttttttgtga gttcataaaa gcgatctgcg
     1921 gcaaaattag ccagttcgcc ttcttcatct tcacctttcc agtcaacgag gtgaataaat
     1981 ccttcgccgc gtagaacttg taaaaatgcc tgtgccagct cgttatttcc gagatcgcca
     2041 ccgctacaat ccaggacgtc ttgcaaccca tattcgtctt catcttcgtc ttcaaagatt
     2101 tcaggttgcg tcgaaagttg agagaaaata gtgggccata aggttgggtt gtgcgataaa
     2161 aaaacgttgg cgacgacgtt gaggtcgtct gcaaaattct tatcccattc aattacataa
     2221 tcttctgaca taacatcaat atcctttctg aatgcctgaa aagacattat tgcattgtta
     2281 agtaaatggc aggaattgat ggaatcttaa aagacggcga taaaaaaggc gaaccggagt
     2341 tcgccattgt gttactccgc cacactctcg cgcagcggtt ttaccggtac aacctttacc
     2401 tgcttaatca tattttcctg tacatcgaga atatcgatat cgtactgctc aatgcgcacg
     2461 cgcgtgccag caaccggaat ttcctccagc gcctccagaa tcaccccgtt gacggtgcgc
     2521 gcgtcatctt ccggcaggtg ccagttaaac gctttattga tttcccggac gttggcggta
     2581 ccgtcaataa tgaccgaacc gtcgttttgc ggcgtgacct cttccgccag tgtcggcgac
     2641 atcgatgtgg tgaagtcgcc aacgatctcc tcgagaatat cttccacggt gaccagcccc
     2701 tggatatcgc catattcgtt gacgaccagt ccgactttct ttttattgcg ctgaaattta
     2761 atcagttgcg tactgagcgg cgtaccttcc gggacgtaat agatttcatc ggcggcgcgc
     2821 agcatcatct ctttggtgaa ctcttttttc tcggccatta accgccaggc ttcacgcacg
     2881 cgcagcatac tgatggcgtc atccagcgaa tcgcgataga gcacaatgcg tccgtgcggc
     2941 gagtgggtga gctgccgctc gatagacttc cagtcgtcat tgatatcgat cccgataatt
     3001 tcattacgcg gcaccatgat gtcatccacg ctgacctttt ccagatcgag aaccgacagc
     3061 agcatatcct gattgcggcg agagatttgc gaacgggatt catgcacgat agtgcgtaat
     3121 tcctctttgc ttaacgaccc gctgaccacg atgtccgttt taattcccat cagacgcatc
     3181 agcaggcggg tgatggtgtt aagtaaccac accagcggca tcatcagtat ctgtaacggc
     3241 gccagcagga agctgctggg ataggccact ttttccggat agagcgcggc gatagttttg
     3301 ggcaggactt cggcaaaaac taacacgaca aacgtcagta ccccggtggc gatagccacg
     3361 ccggcatcgc cgtaaagccg catacccaca atcgtgccga gcgccgaggc aagaatgttg
     3421 accaggttat tgccaatcag caccaggctt atcagtcggt cgggtttacg cagtaatttt
     3481 tctacccgtt ttgccgagcg attaccttgc ttcgccatat ggcgtaaacg gtaacggttt
     3541 agcgtcatca ttccagtttc ggaaccggaa aaataggccg agatgaccac catgatgatt
     3601 aatatgataa tcagcgtggt ggtggagatg tgttccaggg gaaactcctt taaaagctta
     3661 gcttacaaat tgctgtaata tgcggctacc aaaataggcc agcgtcagaa tacccgcgcc
     3721 tgcgacgtta aaccacacga cccgacgacc ccgccagcct tcatggtaat gcccccacag
     3781 cagaacgata tagacaaacc atgccacgat agagagcacg gctttatcaa tattttcagt
     3841 actgaacagg ttatgcatgt aaaacaggcc ggtacacaga gtaagggtca gcagtacgac
     3901 gccaatctgc gtgatatgaa acattttgcg ctcaatgctc atcaatggcg gcatttcatt
     3961 actaaacgcc agctttttgt tcttcaactg atagtcgatc cacgccagtt gtagcgcata
     4021 cagcgcggcg attatcagcg tcgcgtaaga gaaaagcgac agaccgatgt gcaccatcat
     4081 gcctggggtc gcttccagat gcgtaatata ttcattaggc atgaacgtgg cgaaggccag
     4141 gttaatcagc gcaaaagcat agacaatggg cagaagtagc cagccgcgat tacgcgacgc
     4201 gacaatggtc atcaccgtgc agatcatcag gctgaccagc gaaccgacat tcagcaggct
     4261 caggttttgt ccactgtcgc cgccgggcag aatacgcgat tccagcgcga cagcatggca
     4321 caccagcgcg atgaccgcag aaagaatagc catacgccgc cagccgctgt ttttttgcaa
     4381 cagtccggga acgatcagcg cgaggctgaa ggagtaggcg acaagggcaa gtaaagcaaa
     4441 aacgggcata gttgtgtcga cagttgacca gtgagaaaga gaagcagtat agcgttacgt
     4501 gaccgcagct ccaaccgttg cataacaaca aagacggctt catggtatac tgtggcgaaa
     4561 ttctgtaact gtgtcgctgc ggcgaccaac cgtttccacc ccaggcgaga gacaatgttt
     4621 gataatttaa ccgatcgttt gtcgcgcacg ctgcgcaata tcagtggccg tgggcgcctt
     4681 actgaagaca acgttaaaga gacgctgcgc gaagtgcgca tggcgctgct ggaggctgac
     4741 gttgcgctgc cggtagtgcg tgagttcatc aatcgcgtaa aagagaaagc ggttggtcat
     4801 gaagttaaca aaagcctgac cccagggcag gagttcgtca agattgtccg tagcgaactg
     4861 gttgcggcaa tgggcgaaga aaaccagacc ctgaatctgg ctgcgcagcc gccagccgta
     4921 gtattgatgg cgggtctgca gggggcgggt aaaaccacca gcgtcggtaa gttgggtaaa
     4981 ttcttgcgcg agaagcacaa gaagaaagtg ctggtcgtct ctgccgacgt ctatcgcccg
     5041 gcggcgatca aacagctcga aacgctggct gagcaggttg gcgtggattt cttcccgtct
     5101 gatgtcggcc agaaaccggt tgatatcgtc aacgccgcgc tgaaagaagc gaagctcaaa
     5161 ttctacgacg tgctgctggt ggataccgcc ggtcgtctgc acgttgacga agcgatgatg
     5221 gacgaaatca aacaggtcca cgcttctatc aagccagtag aaacgctgtt tgtcgtcgat
     5281 gcgatgaccg gtcaggatgc ggcgaatacc gcaaaagcct ttaacgaagc gctgccgtta
     5341 accggtgtgg tgctgaccaa agttgatggt gatgcgcgtg gcggtgcggc gctctctatt
     5401 cgtcatatca ccggcaagcc gattaaattc ctcggtgtcg gcgagaaaac cgacgcgctg
     5461 gagccgttcc acccggatcg tatcgcctcg cgtattctcg gcatgggcga cgtactgtct
     5521 cttatcgaag atatcgaaag caaagttgac cgcgcacagg ctgagaagct ggcgaccaaa
     5581 ctgaagaaag gcgacggttt cgacctgaac gacttcctgg agcagctcaa acagatgaaa
     5641 aacatgggcg gtatggccag tctgatgggc aaattaccgg gcatggggca gattccggac
     5701 aacgttaaat cgcagatgga tgataaggtg ctggtgcgta tggaggcgat catcaattcg
     5761 atgacgctga aagaacgcgc gaagccggaa atcattaaag gttcccgcaa gcgtcgtatc
     5821 gcgcagggct gtgggatgca ggtgcaggac gttaaccgcc ttctgaaaca gttcgacgac
     5881 atgcagcgca tgatgaagaa aatgaagaag ggcgggatgg cgaagatgat gcggagtatg
     5941 aaggggatga tgccgcctgg ttttccaggc cgctaatttc ccggctaggc tcacttgcta
     6001 tttcggcacc ggggtgtgct agccatcctc acgtactgcg tggccgctaa aacaagggta
     6061 taaggctatc ttgtttgcca ttttagcccc ggggtgtgct cgaaatgctc acgtactgcg
     6121 tgtacgctcc gctttctgcg cgcacgccgg agctaaactg gctgcaccga tatacgcctt
     6181 ttatcccttg tttcgtgttc agtagcaaga tgctgattgc attttcccca gaaatcagta
     6241 aaattttcgg gcttttaata tgacgccggg ctccgttcct cgatgaggcc cggttgtttt
     6301 attcacacaa gaggatgtta tggtaactat tcgtttagct cgtcacggcg ctaaaaagcg
     6361 tccgttctac caggttgttg tcaccgacag ccgtaatgca cgcaacggtc gcttcattga
     6421 gcgcgttggt ttcttcaacc caatcgctag cgaaaaagaa gaaggcaccc gcctggatct
     6481 ggatcgcatc gctcactggg ttggccaggg cgcaaccatt tccgatcgcg ttgcggcgct
     6541 gatcaaagaa gtaaaaaaag cagcttaatc tgtcacggtg gtcatgatga gcaagcaact
     6601 cgccgcacaa gtacccgctg aaccggttgt actggggaaa atgggttctt catacggtat
     6661 ccgtggttgg ctcagagtgt tttcctccac tgaagacgcc gaaagcattt ttgactatca
     6721 gccctggttt atccagaagg cgggtcagtg gcagcaggta cagctggaaa gctggaagca
     6781 ccacaatcag gatctgatca tcaagctgaa aggcgttgac gatcgagatg ccgcgaatct
     6841 tctgaccaat tgcgaaattg tcgtggattc ctcgcaactt cctgcgcttg aggagggaga
     6901 ctactactgg aaagacctga tgggttgcca ggtagtcacc gctgaaggct acgatctcgg
     6961 taaagttatc gacatgatgg aaaccgggtc gaatgacgtt ctcgtcatta aggcgaacct
     7021 gaaagatgca tttggtatca aggaacgact agtaccgttc ctcgatgggc aggttatcaa
     7081 gaaagtcgat ctcgctactc gtactatcga agtagactgg gatcctggtt tttaaaccac
     7141 cggataaacg gtaataaatg gcgttatggg gattggcttg tgtttattgg catcgttagc
     7201 ctgtttcctg aaatgttccg cgcaattacc gattacgggg taactggccg ggcagtaaaa
     7261 aaaggcctgc tgaacatcca aagctggagt cctcgcgact tcgcgcatga ccggcaccgt
     7321 accgtggacg accgtcctta cggcggcgga ccggggatgt taatgatggt gcaacccttg
     7381 cgggacgcca ttcatgcagc aaaagccgcg gcaggtgaag gcgctaaagt gatttatctg
     7441 tcgcctcagg gacgcaagct tgatcaagcg ggcgttagcg agctggccac gaatcagaaa
     7501 ctcattctgg tgtgtggtcg ctacgaaggc gtagatgagc gcgtaattca ggccgaaatt
     7561 gacgaagaat ggtcaattgg cgattacgtt ctcagcggtg gcgaactacc ggcaatgacg
     7621 ctgattgact ccgtcgcccg gtttataccg ggggttctgg ggcatgaggc atcagcaatc
     7681 gaagattcgt ttgctgatgg gttgctggat tgtccgcact atacgcgccc tgaagtgtta
     7741 gaggggatgg aagtaccgcc agtattgctg tcgggaaacc atgctgagat acgtcgctgg
     7801 cgtttgaaac agtcactggg ccgaacctgg cttagaagac ctgaacttct ggaaaacctg
     7861 gctctgactg aagagcaagc aaggttgctg gcggagttca aaacagaaca cgcacaacag
     7921 cagcataaac atgatgggat ggcataggcc cccgaatatc agtttaccca ggataagaga
     7981 ttaaattatg agcaacatta ttaagcaact tgaacaagag cagatgaagc agaacgtacc
     8041 ttccttccgt ccgggcgata ccgtggaagt gaaagtatgg gttgttgaag gtaccaagaa
     8101 acgtctgcag gcattcgagg gcgtggttat cgctattcgt aaccgcggtc tgcactctgc
     8161 attcactgtt cgtaaaattt ccaacggcga aggcgttgag cgtgtcttcc agactcactc
     8221 tccggtagtt gacagcattg ctgttaaacg tcgtggtgct gttcgtaaag ctaaactgta
     8281 ctacctgcgt gagcgtactg gtaaagcagc tcgtatcaaa gagcgtctta actaagaacg
     8341 cgctttcgca acatccgaaa gcttgtagaa aagaaggggc tggcattacg ctggcccctt
     8401 tttttatggg ttgctccacg ccatagacgg ttgcatgatt aagctgggtc tgtggtatca
     8461 acgctgagtc agaaacggcc tggcccgttc cttagtttag cgagcgttct gcacgccggt
     8521 gtttagcctg atacatattt cgatcggcca gttcttgtag tttttcggca gtggcatgtt
     8581 cccatgtcag cgcaaagcca atactcaggg tcatcgttat tcgctggccg ttatgcagtt
     8641 caaaaggtcg attaaacgcc tgggatagtg ctgcgcaaat acgttgtact tcatactccg
     8701 aatgtacacc gtaaagcacc atcgcaaatt catcgccgcc gagtcggtaa gtctgataac
     8761 ggctaccacc gaattccgct aatcttttgg caacctctat aagtacgcgg tcgcctgccg
     8821 catgtcccca ggtatcatta atatatttaa agttatcgcc atccagaaat aacaatgccg
     8881 aactgctacg agcggaattg tccttcatca gcgcgttaat acagctgcga aatgccgcgc
     8941 gattggcaag ccccgtcagc ggatcgtgca acgcggtacg tagtaattgt gcatttttag
     9001 cctgaagccg tagctgccat tcttccatct catccagaag gctattgaaa tcctgcgcaa
     9061 acaggtgaaa ttccgcaata cgctcatcag gtacccggcg tgaaaaattt cggttagtgc
     9121 gaacgtcgtg tacaatttca gtaatatttt gtagcgcatc cacaacgcca ttgtgtaaat
     9181 aacgcgtgag tagcagggca atgccggatg ctagcagaat acatcctgtc agcactgcca
     9241 gcgatagcca gataaaatga ccaataaggc tgtcgcgggc gacaagccgt acttcgccga
     9301 tagccctgcc gttgtgccag acgggttgcg ataccggcaa tggaaaaagc cagtggctaa
     9361 ttaagccgat gagcttatcg tctgcggctc gcgcatcata tcgccatgag gcgatagtac
     9421 ggccattttt atcgcggacc tccgccgctg aaaattgtcc ctggcgtccc agtgtggcga
     9481 gcgtttccgc tgcggccgcg ctatcggaaa ataccagtgc cgcttcaagg ctatgggcca
     9541 ttgtggcggc ggtcaaatcg agattctttt gcgcatactg tttgagcgta aggacagacg
     9601 caacgcaaat taatagccag atcaatgtca ttgtaagcag cacgctgatt atactaatcc
     9661 gccgtagtgt gcgtttaaat gttggtctgg acagagaaaa ttccttattc atgcttttga
     9721 ttccgtgcaa gcattaatac ttctggattc actctcacgc cgctatgcga gagggagtcc
     9781 aggttgacgg aaaatttgac ttcatcattg ttaatgatca gacaaaatgc gctgccaata
     9841 atacattcgg tattttgctc ggcaattaat aacaaggcat taactggata atgacgcgtt
     9901 aactccacct gataagctgg cgattcattg ccaaagtaaa aaccatcaca gcgggcgctc
     9961 agggcttctt gtgtggtacg gatgacaagc ggttgataag ggaaagccca gttagcctct
    10021 tcgctaagta ccctgacaaa acgcgcagat gaaaatatgc atagccttgg cggcccggat
    10081 aacgctggcc agtgtgtata actgacgata ccggagacaa tggcgcgtac ggatttctct
    10141 tcttccgtga cacattgagc atacagaggc aagcttgcta ataatagcga taacagaagg
    10201 ataaatcggt gagaaaaacg cattaacaag tccccaccat cttcagtcgt aaaacattaa
    10261 aatacatccg tgattgtttg tagcaaaat
//
LOCUS       DAJVKX010000146        10109 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.146, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000146 DAJVKX010000000
VERSION     DAJVKX010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10109
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.146"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(1..455)
                     /locus_tag="OPY25_003838"
                     /pseudo
     CDS             complement(1..455)
                     /locus_tag="OPY25_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001674837.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD15/CS22/SEF14 family fimbrial major subunit"
     gene            810..1959
                     /locus_tag="OPY25_003839"
                     /pseudo
     CDS             810..1959
                     /locus_tag="OPY25_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1991..2131)
                     /locus_tag="OPY25_003840"
                     /pseudo
     CDS             complement(1991..2131)
                     /locus_tag="OPY25_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008322911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
     gene            complement(2868..5201)
                     /locus_tag="OPY25_003841"
     CDS             complement(2868..5201)
                     /locus_tag="OPY25_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCS0929336.1"
                     /translation="MKMNVTETVKQACGHWSRILPALGVKVIKNRHQACPVCGGSDRF
                     RFDDKEGRGTWFCNQCGAGDGLKLVEKVFGVSASEAAGKVDAVTGNLPPVALEVIAAA
                     EAETEADRKAAAALAVKLMEKTRPASGNAYLTRKGFPGHECVMLTATHKTGGVTFRAG
                     DMVVPLYDNAGALVNVQLINSDGLKRTLKGGAVKGACHTIEGKKQAGKRLWVAEGYAT
                     ALTVHHLTGETVMVALSSVNLLSLASLARQKHPACQIVLAADRDLNGNGQSKAAAAAD
                     ACEGIVALPPVFGDWNDAFMQKGEEATRKAIYDAIRPPADSPFTTMSEAEFTAMSTSE
                     KAMRVHEHYGEALAVDANGQLLSRYEAGIWKIIPPSDFARDVAGLFQRLRAPFSSGKI
                     ASVVETLKLIIPQQDAPARRLIGFRNGVLDTATGTFSPHHKSHWLRTLCDVDFTSPVE
                     GETLETHAPHFWRWLDRAAGGKPEKRDVILAALFMVLANRYDWQLFLEVTGPGGSGKS
                     ILAEIATMLAGEDNATSATIETLESPRERAALIGFSLIRLPDQEKWSGDGAGLKAITG
                     GDAVSVDPKYKDAYSTHIPAVILAVNNNPMRFTDRSGGVSRRRVIIHFPEQIAPEERD
                     PQLRDKIARELAIIVRQLMQKFSDPMTARTLLQSQQNSDEALSIKRDADPTFDFCGYL
                     EMLPQTNGMFMGNASIIPRNYRKYLYHAYLAYMEANGYRNVLSLKMFGLGLPMMLKEY
                     GLNYEKRHTKQGIQTNLSLKEESYGDWLPKCEEPAAT"
     gene            complement(5216..5536)
                     /locus_tag="OPY25_003842"
     CDS             complement(5216..5536)
                     /locus_tag="OPY25_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5375 domain-containing protein"
                     /protein_id="HCS0929337.1"
                     /translation="MKNPLPPVLRAALYRRAVACAWLTLCERQHRYPHLTLDALESAI
                     AAELEGFYLRQHGEEKGRQIACALLEDLIEAGPLKAAPSLSFLGLTVMDELCARHITA
                     PVLH"
     gene            complement(5533..5760)
                     /locus_tag="OPY25_003843"
     CDS             complement(5533..5760)
                     /locus_tag="OPY25_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929338.1"
                     /translation="MRHTTITARDLECLEHMRNVGQLVNELMQVQDCATVRRDPVQQS
                     QLTSVIYLMTAQLDGVVERCNQRWLTGEGNV"
     gene            complement(5757..6308)
                     /locus_tag="OPY25_003844"
     CDS             complement(5757..6308)
                     /locus_tag="OPY25_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004153681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="HCS0929339.1"
                     /translation="MMMTIQQTAPFSGLLLFIVSRYSFPAVAKSAAGRGNPSNLTATP
                     DAPCVFFCVYALVHLLLAQWFHDLCSYRVMVAQAGPTSVGPVSVRAGISTPVWATTTE
                     RGNSGGSITCYLTEVALMATILTPSYPQFVFVFAAVRRADRKPRICMLRTVAGDEQAA
                     RLSLVRDYVLSFAGRLPVAEVRA"
     gene            complement(6305..6571)
                     /locus_tag="OPY25_003845"
     CDS             complement(6305..6571)
                     /locus_tag="OPY25_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HCS0929340.1"
                     /translation="MHTAFSSPSSAPAAPLMPVSDTVHERFIRLPEVMHLCGLSRSTI
                     YDLISREAFPKQISLGGKNVAWAQSEITAWMTDRIAERNRGYDA"
     gene            7111..7854
                     /locus_tag="OPY25_003846"
     CDS             7111..7854
                     /locus_tag="OPY25_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001472073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HCS0929341.1"
                     /translation="MKPELIIKSMQTVISKQDEGAEQRIAGALVALNEAKDAHTASMG
                     KLSDIEASIQRCEQERQTALSESAQAEQDWRSRFRTLRGNLTPELKAEHSKRIASREL
                     ADEFTGLITELEKDKSLAMLGACSSGTAYISAHEKAFTTYANSEWKKALAGISPALLR
                     AFLLRIRSLEMSGETSLRATVTRELGDALNMQSALYHFDMEQEPVLSVTGMNRPVITG
                     VDMALLRSPARRMKLAAELAAKDHEQAEG"
     gene            7858..8097
                     /locus_tag="OPY25_003847"
     CDS             7858..8097
                     /locus_tag="OPY25_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HCS0929342.1"
                     /translation="MFHCPFCKKTAHVRTSRYLSENVKQRYHQCTNIECSATFRTIES
                     VDGVIRAAPEKPDPAPVTPPPPRKVQGCYSSPFRH"
     gene            8113..8679
                     /locus_tag="OPY25_003848"
     CDS             8113..8679
                     /locus_tag="OPY25_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Polarity suppression protein"
                     /protein_id="HCS0929343.1"
                     /translation="MTTVTIQQAFEACQTNKNTWLKRKAELADLEREYREQLLAGDEQ
                     IPRRMQDLRDNIDVKKWEINQAAGRYIRSHEEVQHISIRNRLHDFMQQHGAELAATLA
                     PELMGYHEQIPAVKQSAMQHSVDYLREALSVWLAAGEKINYSVQDNDMLTTIGFRPDA
                     ASRDDNREKFTPAQNLIYTRRRAELATR"
     gene            8955..>10109
                     /locus_tag="OPY25_003849"
     CDS             8955..>10109
                     /locus_tag="OPY25_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929344.1"
                     /translation="MFTERLARWLARSSAKSGINRPEDLNAVLSTDIGLVRAENQDLI
                     AAIRVNTPSNVGNPFFAMALLDGMGGMQDGKQCATIALSTLFYSLIKFRSDPPESRLL
                     KATLEANSVVYDYAKGHGGSTLSAVIIENGSAPVIVNVGDSRIYSFSLDCGLTAISSD
                     DSLEALGGRGRGLLQFIGMGESIKPHINILDKNHKNIILTSDGTHFISHSAFEELLSH
                     SSDFSTSAQRIAQYVQWCGAKDNASFGIINCNDIENSLNSHKDIGVELWDPHGNLHIM
                     WMKNYPAAQNYFSQNIVDDQDKEPSPIIDDDGFENKKTLNNPSTKNLELDSETPQREL
                     FSNESPEKSQDPSITSKAIKQRKNKDKKKAIEKIKKDQSVMINIKDEENKN"
BASE COUNT         2589 a         2541 c         2613 g         2366 t
ORIGIN      
        1 acctgctggc agggtcgatt taccaaaggt tgtgacaggg acatttagcg tttcttgaga
       61 gctggcaact cgccaacctg caagcccgtc aattccagta tttgcttggt cattaatatt
      121 ggctccctga atatacccac ggaaaacagg ctgtccttgt ccatcaacga acgggacagt
      181 ggctacacca ccagataccg aagcccctta cctgcaatag atactgagtt atgtggacca
      241 gtagcagtaa tgctgagagt accaactttc tgaccagcag caacatcagg ccctgtaaag
      301 ccaggatcct gactccagtt ggctgatgtt gtattctgag ctgcaatagt aaccgctgcc
      361 tgaacctctg ctttgttacc aacaaagcca gctgcgtggg cactgccaca tgcaattaaa
      421 gcaagaactg ctactgcaga tgctgattta cgcatattac aaaatctcca aaaatcaact
      481 attagcattc gcacaattta tctgtgcgga tgctaatata ctcgcgccat tttaaaaatt
      541 taagcaaaaa acaaggatca ctattttttt atctttacac gcccccccca ttaataagcg
      601 aatgatccat taatactttt tgtggaatat ctaatatcca catgtttaaa aaatttcata
      661 tcaacccttt atttaaaaag cataaacaaa aaaatacatc caaataaaaa tgtttatgtt
      721 atttattgag agaatgggtt gtctgatctt acccagcaag agtggacatg cgactaagtg
      781 agtaaactct caagaaagag gtgtctcaca tgacaaaagc agcatcaacc accaaaaagc
      841 catgcaagca acatacgcct gaatttcgcg acgaagcctt gaaactggct aacgcattgg
      901 gatggctgcg gctaccagcg agcttaacct gtatgaatcg cagctctaca actggcgaag
      961 aaaacagcaa aatcagctct cttcttctga acgcgaatag gagatgtccg cagagatcgt
     1021 ccgtctgaag catcaactgg cagaacggga tgaggaactg actattctcc agaaggtcgc
     1081 gacatacttc gcgaaacgcc tgaaatgaag tatgtcttca tcgaaaaaca tcaggctgag
     1141 ttcagtatca aagccatgtg ccgtgtactt caggttgccc gtagtggctg gtacgtctgg
     1201 catcagcgtc gtcatcagat aaaccagcgt cagcagttcc gccttgtctg tgataacgtc
     1261 gcccgggagg cattcagtga cgcaaacagc gctatggtgc gccacgcctg acggatgagc
     1321 ttcgtgctca gggacgggtg tataccgtag cggccagcct gcgccggcag gcgctgcggg
     1381 cgaaagcttc acggaagatc agtccagtca gttaccgcga acatggtctg ccagtccaga
     1441 gaatctgctg aagcaggact tttacgtcag tggcccgaat cagaaatggg tgggtgacat
     1501 catgtatctt cgcaccggtg aaggctggct ttatctggcc gtggttattg acctgtggcc
     1561 gcagtcagcc actggctggt ctatgtcctc gcggatgacg gcacagtttg cctgcgatgc
     1621 attacacata gcgctgtggc ggcgtaaacg accggaaaag tcaccatata tacagacaga
     1681 ggcagtaagt actgttcagc ggattaccag agcttactga aacggcataa tctgcggggc
     1741 aggatgagcg ccagaggctg ttgttacgat aatgcctgtg cggaaagctt cttccacacg
     1801 ctgaaggtgg aatgtatgca tggagaggac tttgccagcc gggaaataat gcgggcagca
     1861 gtgtttaatt atattgagtg cgattacaat cgctggcgtc gccacagtgc ctgtggcggt
     1921 ctcagtccgg aacaatttga aaaccagaac cgcgcttaag gttgtatccc tattacgcgg
     1981 gtaggatcag tttacccccg aaacggtatt ggagttgcca gtattttgaa ccattggggt
     2041 tgatcagcag gtgcataccc tgcccatctg tgagtttgaa gggtttgtcg gagggcttgg
     2101 tagtcctaac tttgatatcg gtgagagcca tcagttgata cctccagtgt tggtaccaaa
     2161 atcaatcgaa ccgggaatac catcagttat accatcatcg gttggtatat gttcaaggaa
     2221 ttgagtagac gtgaacagac taagccaagt cagaaattcg cttaacttac tgtttttgtg
     2281 gattaaagta gacgttagta gacttgaaaa aagctttgta tggtgcgaag gccggactca
     2341 aaacacaaca taataaattg aaaataaagg aaataaagaa gaacacatgt tcatgtgccc
     2401 ccttttgtgc ccccatggct ttttaagccc cttaagttca caactgattg gtattaaaaa
     2461 ggaaattgtt attttcccca tcggttaggt tccgatatac ggatcctaac cggggtaata
     2521 ttgaacatca gtaaaattct ttttttccat ataactgttc acactgttca cctcttcact
     2581 tttcttttta atatcatggt gataagtggt gatgagttgg tgaagagtga acaatcgact
     2641 cttcacattt gtgatttttg ctcgtcctgg atgcgcctgg tcaggcgatg cgcagggtga
     2701 taaaaagttt tttcaggttt tattgttcac actgttcacc tctggttttt tatcaataat
     2761 ttcatggtga tacagggtga atatacggtg aagggtgaac agtggagtgt tcaccctgtg
     2821 gcaatgtcca gaaagaaaaa gaccggctgt tgccggtctg gagttggtta tgttgctgcg
     2881 ggttcctcgc atttcggcag ccagtcgccg tagctttcct ctttcagcga cagattggtt
     2941 tgtatcccct gctttgtgtg ccgcttctca taattcaggc cgtattcttt cagcatcatg
     3001 ggcagcccca gcccgaacat tttcaggctg agcacgttcc tgtacccgtt agcctccata
     3061 taggccagat acgcgtgata aagatattta cggtaattac gcgggataat actggcatta
     3121 cccataaaca tcccgttggt ctgcgggagc atttccagat agccgcaaaa atcaaacgtc
     3181 gggtcagcat cgcgcttgat actgagtgcc tcgtcggagt tctgctgtga ctggagcagt
     3241 gtgcgcgctg tcatcgggtc gctgaacttc tgcataagct gacgcacaat gatggccagc
     3301 tcgcgcgcaa ttttatccct gagctgcggg tcgcgttcct ccggggcaat ctgctccggg
     3361 aagtgaataa tcacccggcg gcgcgataca ccaccgctgc ggtcggtaaa gcgcatcggg
     3421 ttattgttca cggccagaat caccgctgga atatgggtgg agtacgcatc cttgtatttc
     3481 gggtcaacgg agaccgcatc cccgccggtg atggccttga gtcctgcccc gtcaccgctc
     3541 catttttcct ggtcaggcag tcgtatcaga gagaagccaa tcagcgcagc gcgttcgcgg
     3601 ggtgattcca gcgtttcgat ggtggccgac gtggcgttat cttccccggc aagcatggtc
     3661 gcaatttcgg ccagaatact ttttccgctc ccgccggggc cggtgacttc gagaaagagc
     3721 tgccagtcgt aacggttcgc cagaaccata aacagcgcgg ccagaatcac atcgcgtttt
     3781 tccggtttgc caccggcagc gcggtcaagc cagcgccaga aatgaggggc gtgggtttcc
     3841 agcgtttcgc cctccaccgg tgaggtgaaa tcaacatcac atagcgtgcg cagccagtgc
     3901 gatttgtggt gcgggctgaa agtgccggtg gcggtatcga gtaccccgtt acgaaaacca
     3961 atcagacggc gcgccggtgc gtcctgctgc ggaataatca gtttcagggt ctccaccact
     4021 gaggcaattt tccccgacga gaacggggcg cgcagacgct gaaacaaccc ggccacgtcg
     4081 cgggcaaaat ccgacggggg aatgattttc catattcctg cctcatatcg ggacaggagc
     4141 tggccgttcg catccacggc cagcgcttcg ccgtaatgtt catgcacccg cattgccttt
     4201 tcactggtgc tcatggcggt aaattccgct tcgctcatgg tagtgaaagg gctgtcagcc
     4261 ggaggccgga tggcgtcata aatggctttc cgcgtggcct cttcaccttt ctgcataaac
     4321 gcatcattcc agtcaccgaa caccggcggc agggcgacaa tgccctcgca ggcgtctgcg
     4381 gccgcagcgg ctttactctg gccgttgccg ttaaggtcac ggtcggcggc gaggacaatc
     4441 tgacaggccg ggtgtttctg acgggcaagg ctcgccagag aaagtaggtt cacggaggac
     4501 agcgccacca tgacggtttc cccggtcagg tgatgtacgg tgagcgcggt cgcatagccc
     4561 tccgcaaccc acaggcgttt tcccgcctgt tttttccctt cgatggtgtg acacgctcct
     4621 tttaccgccc cgcctttcag ggtgcgtttg agaccgtcag aattaataag ctgaacgtta
     4681 accagcgccc cggcattgtc atacagcggg acaaccatat caccggcgcg gaacgtcacg
     4741 ccgccggttt tgtgtgtggc cgtcagcatg acacactcat gaccggggaa tcccttgcgg
     4801 gtgaggtagg cgttgccgct ggccggtcgg gttttctcca tgagctttac ggccagcgcg
     4861 gccgccgctt tgcggtcagc ctccgtttct gcttctgcgg ccgcaatcac ttccagggca
     4921 accggcggca ggttgccggt cacggcatcc acctttccgg cggcctcgga ggccgacacg
     4981 ccaaatacct tctcaaccag cttaagcccg tcacccgcgc cgcactggtt gcagaaccac
     5041 gtcccgcgtc cctctttatc gtcaaagcgg aaacggtcag agccgccgca caccggacag
     5101 gcctgatggc ggtttttaat caccttcaca cccagcgccg ggagaatacg cgaccagtgg
     5161 ccgcaggctt gttttaccgt ttccgttacg ttcattttca tgtttatttt ctccctcagt
     5221 gcagtaccgg tgcggtgata tgacgggcgc aaagctcatc catcacggtc agcccgagaa
     5281 aggacagcga cggtgcggcc ttaagtggcc cggcttctat taaatcttcc agcagtgcac
     5341 aggcaatctg gcggcctttt tcctctccgt gctggcgcag gtagaagccc tccagctcgg
     5401 cggcaatggc gctttccagc gcgtcgaggg tgaggtgcgg atagcggtgc tggcgttcgc
     5461 acagggtcag ccaggcacag gccacggcgc gacgatacag cgcggcgcgt aatacgggcg
     5521 gtaatggatt tttcatacgt tgccctcccc ggtcagccag cgctgattgc agcgctctac
     5581 cacgccgtca agctgggcgg tcatgaggta aatcaccgag gtgagctgtg actgctgcac
     5641 cgggtcgcga cgaacggtgg cgcagtcctg cacctgcatc agctcattga cgagctggcc
     5701 gacgttgcgc atatgctcca gacattcgag gtcacgggcg gtaatggtgg tgtgtctcat
     5761 gcgcgcacct ccgcaaccgg cagacgacca gcgaacgaga ggacgtaatc gcgaacgagg
     5821 gaaagacgtg cggcctgttc atcaccggca acggtgcgaa gcatacagat acggggttta
     5881 cggtctgcgc gacgaacagc ggcaaacaca aagacaaact gcgggtatga cggggtgagg
     5941 atcgtagcca taagggcaac ctccgttaga tagcaggtta tgctaccacc ggagtttcca
     6001 cgctcagtgg tggtagccca gacgggggtg gaaataccgg ctctaacgga taccggcccg
     6061 accgaagtcg gccccgcctg agccaccatt actcgatagc tgcaaaggtc atgaaaccat
     6121 tgcgcaagta acaggtgcac gagggcatag acacaaaaaa agacgcatgg cgcgtcaggt
     6181 gtcgccgtta gattactcgg gtttccacgc ccggctgccg attttgcgac agcgggaaaa
     6241 ctatacctgg aaacgataaa aagaagcaag ccagaaaaag gggctgtttg ctgaatggtc
     6301 atcatcatgc gtcataaccc cggttgcgtt cggcaatgcg gtcagtcatc catgccgtga
     6361 tttcagactg cgcccacgcc acgttttttc cgccgaggga gatttgtttc gggaaggctt
     6421 cccggctgat gaggtcgtaa atggtcgagc gggacagacc gcacagatgc atcacttcgg
     6481 gcagacgaat aaaacgctca tgaacggtat cagaaaccgg catcagcggc gcggcagggg
     6541 cagaagacgg ggaagaaaaa gcggtgtgca tcgggctacc tcacaaagtc catacagtgc
     6601 cggtcgtgtc cgtccggctt cgggtagctc tctattttgt gaatattttt acgcagggca
     6661 acaagtcatt ttgtagtact ccaccacaca acagagcgat ttttatacag tggcaaacgt
     6721 tggccgtttt ttggcaaacg ttggcaaacc ggtggcccat tgctgattac ttttgtttat
     6781 atatttcttt ttttaatcgc taaaaaatct aagaagctgg ctggctgaac aaagtgaagg
     6841 gtgaacagtg gtgaacagac ggtgaacact cagaccttca actattcacc ctttaactca
     6901 ctgtattact tatcttttta tttaaggtga acagtggtga atagttatta gtaaaaaaac
     6961 aaacggtgag tcaggttttc ctgagacctt tctgtggcca gccggttttt aaggtctgtt
     7021 tgtgccagca ctctgacaac ggcaatgaat cgtgttgttg tgcaggaggc gtcagaatca
     7081 tttcaggttg aacacacgga gagcctgaac atgaaacccg aactcattat caaatccatg
     7141 cagaccgtta tcagtaaaca ggatgaaggc gcggaacaac gcattgccgg tgcgctggtc
     7201 gcacttaacg aagcaaaaga cgcacacacg gccagcatgg gtaaactcag cgacattgag
     7261 gcttccattc agcgttgtga gcaggaacga cagaccgccc tcagtgaaag tgcacaggcc
     7321 gaacaggact ggcgcagccg ctttcgaact ctgcgcggca acctcactcc tgaactgaaa
     7381 gctgaacaca gtaaacgtat cgccagccgc gaactggctg atgagttcac cggtctgatt
     7441 accgagctgg agaaagacaa aagcctcgcc atgcttggtg catgctcctc cggtacggct
     7501 tatatcagcg cccatgaaaa agcgttcact acctacgcca acagcgagtg gaagaaggcg
     7561 ttagccggta tcagccccgc actgttacgt gcctttctgt tgcgtattcg gtcgctggaa
     7621 atgagcggag aaacctcgct gcgtgcgacc gtgacccgtg agctgggtga tgccctgaat
     7681 atgcagtcag ccctgtatca ttttgatatg gagcaggagc cggttctgtc cgtaacgggc
     7741 atgaatcgcc cggtcataac cggggttgat atggcgctgt taagaagccc ggccagacgg
     7801 atgaagcttg ccgctgaact ggccgcaaaa gaccacgaac aggcagaggg ctgaattatg
     7861 tttcactgtc cgttctgcaa aaagaccgcg cacgtccgta ccagccggta tctgtcggaa
     7921 aacgtcaaac agcgttatca ccagtgtacc aatatcgaat gttcggccac tttccgcacc
     7981 attgagtcgg ttgacggtgt gatacgtgct gcaccggaga aacccgaccc cgcgccggtg
     8041 acgccaccgc cgccgcgtaa agtacagggc tgctacagct cgccgtttcg gcattaatca
     8101 ggagagagac tcgtgaccac tgtgaccata cagcaggcct ttgaggcctg tcagacgaac
     8161 aaaaatacct ggctgaaacg taaagccgaa ctggcagacc ttgaacggga ataccgtgaa
     8221 cagctccttg ccggtgacga acaaatcccg cgcagaatgc aggatttgcg cgacaatatc
     8281 gacgtgaaaa agtgggagat taatcaggcc gccggtcgct atatccgctc acatgaggag
     8341 gtacagcaca tcagcatccg caaccggctc catgacttta tgcagcagca cggcgcggag
     8401 ctggccgcca cgctggcgcc tgagctgatg ggatatcacg aacaaattcc cgcagtaaaa
     8461 cagagcgcca tgcagcactc ggttgattat ctgcgtgaag ccctgtcggt gtggctggcc
     8521 gcaggtgaaa aaattaatta ttccgtgcag gacaacgata tgttaacgac catcggattc
     8581 aggcctgatg cggcttcgcg ggatgataat cgcgagaaat tcactccggc acagaacctg
     8641 atttacaccc gccgacgtgc agaactggcc acacggtagt acgcgaaaaa atcccccgaa
     8701 aattccgcta tttttcctga aaaaagccat gcatccataa ggtgcatggt tttgcatgca
     8761 aatccccgta ttttttatcc cacgcaacac cagtgctggt gcggcctgag gacgttcatg
     8821 cacctgcatt aaaagcgacc tcttaagcgg gcaggcgtgg cggggagagc attgcgcgcg
     8881 agctctttcg tattaattga caattggtta gctcattgcg aaagtaaact cccccacaat
     8941 aaaacggaat tactatgttt acagaacgac ttgctcgctg gttagctcgt tcttcggcca
     9001 aaagcggcat taaccggcca gaagacctca acgctgtcct tagcacggat ataggactgg
     9061 ttagagctga gaatcaggat ctaatagccg cgattagagt taacactccg tcaaacgttg
     9121 gcaatccttt ttttgcaatg gcgttattag atggcatggg tggaatgcaa gatggaaagc
     9181 aatgcgcaac aattgcttta tcaactttat tctattcttt gattaagttt agaagtgatc
     9241 ctcccgagtc tcggttatta aaagcgactt tagaagcaaa ctccgttgta tatgactatg
     9301 caaaaggaca tggcggttca acattatccg ctgtaattat tgaaaatggg tctgctcctg
     9361 taattgtcaa cgttggcgac agtcgaatat atagcttttc tctggactgt ggacttacag
     9421 caattagcag tgatgactct ctagaagcat tgggtggcag agggcgcgga ttactccagt
     9481 ttataggaat gggggaatct ataaagcctc atatcaatat cttagataaa aatcataaaa
     9541 atataatatt gacatccgat ggaactcatt tcatttctca ttcagcattc gaagagttat
     9601 taagtcattc atctgatttt tctacatcag cgcagagaat agctcaatat gttcaatggt
     9661 gcggtgcgaa agataacgct tcatttggaa ttattaattg caatgatata gaaaacagcc
     9721 tcaactccca taaagatatt ggtgtagagt tatgggaccc tcatgggaat ctacatatca
     9781 tgtggatgaa aaattatcct gcagcgcaga attacttctc tcaaaatata gtggatgatc
     9841 aagataaaga accttcacct attatagacg atgatggttt tgaaaataaa aaaacactaa
     9901 acaatccttc aacaaaaaat ctagaattag attctgaaac gccacaaaga gagctattct
     9961 caaacgaatc cccagaaaaa tctcaagatc catccattac aagcaaagca atcaaacaaa
    10021 gaaaaaacaa agataaaaag aaagctattg aaaagatcaa aaaagaccaa tctgtaatga
    10081 taaatatcaa ggatgaggaa aacaaaaat
//
LOCUS       DAJVKX010000147        10071 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.147, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000147 DAJVKX010000000
VERSION     DAJVKX010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10071
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.147"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..928)
                     /gene="sapB"
                     /locus_tag="OPY25_003850"
     CDS             complement(<1..928)
                     /gene="sapB"
                     /locus_tag="OPY25_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HCS0929345.1"
                     /translation="MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLLHWDFGVSSINGQLISEQLKEVFPATMELCILAFGFALMVGIPVGMLAGVT
                     RSKWPDRFISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFA
                     IIDAWISDSPWRDEMVMSAIRHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAI
                     RQQDYAAISAGVMVIGSLVIVVNVISDILGAMA"
     gene            complement(925..2574)
                     /gene="sapA"
                     /locus_tag="OPY25_003851"
     CDS             complement(925..2574)
                     /gene="sapA"
                     /locus_tag="OPY25_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HCS0929346.1"
                     /translation="MRLVLSSLIVIAGLLSSQATAATAPEQTASADIRDSGFVYCVSG
                     QVNTFNPQKASSGLIVDTLAAQLYDRLLDVDPYTYRLVPELAESWEVLDNGATYHFHL
                     RRDVSFQKTAWFTPTRKLNADDVVFTFQRIFDRRHPWHNINGSSFPYFDSLQFADNVK
                     SVRKLDNNTVEFRLTQPDASFLWHLATHYASVMSAEYAAQLSRKDRQELLDRQPVGTG
                     PFQLSEYRAGQFIRLQRHDGFWRGKPLMPQVVVDLGSGGIGRLSKLLTGECDVLAWPA
                     ASQLTILRDDPRLRLTLRPGMNIAYLAFNTDKPPLNNPAVRHALALSINNQRLMQSIY
                     YGTAETAASILPRASWAYDNDAKITEYNPQKSREQLKALGIENLTLHLWVPTSSQAWN
                     PSPLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMNHDLTLSGWATDSNDPDSFF
                     RPLLSCAAINSQTNFAHWCNPEFDSVLRKALSSQQLASRIEAYDEAQNILEKELPILP
                     LASSLRLQAYRYDIKGLVLSPFGNASFAGVSREKHEEVKKP"
     gene            complement(2686..3666)
                     /gene="pspF"
                     /locus_tag="OPY25_003852"
     CDS             complement(2686..3666)
                     /gene="pspF"
                     /locus_tag="OPY25_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HCS0929347.1"
                     /translation="MAEFKDNLLGEANCFLEVLEQVSRLAPLDKPVLIIGERGTGKEL
                     IANRLHYLSSRWQGPLISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMLVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVKEGT
                     FRADLLDRLAFDVVQLPPLRERQSDIMLMAEHFAIQMCRELRLPLFPGFTDRAKETLL
                     HYAWPGNVRELKNVVERSVYRHGSSEHPLDEIVIDPFQRYPAEPPAPALPAASATPDL
                     PLNLREFQLQQEKALLQRSLQQAKFNQKRAADLLALTYHQFRALLKKHQL"
     gene            3837..4505
                     /gene="pspA"
                     /locus_tag="OPY25_003853"
     CDS             3837..4505
                     /gene="pspA"
                     /locus_tag="OPY25_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HCS0929348.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     SNSARALAEKKQLSRRIEQATAQQTEWQEKAELALRKDKDDLARAALIEKQKLTDLIA
                     TLEQEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAASSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHRFGKQQSLDQQFANLKADDEISEQLAQLKAKMK
                     QDNQ"
     gene            4565..4789
                     /gene="pspB"
                     /locus_tag="OPY25_003854"
     CDS             4565..4789
                     /gene="pspB"
                     /locus_tag="OPY25_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HCS0929349.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRAGRGELSQSEQQRLL
                     QLTDDAQRMRERIQALEDILDAEHPNWRER"
     gene            4789..5148
                     /gene="pspC"
                     /locus_tag="OPY25_003855"
     CDS             4789..5148
                     /gene="pspC"
                     /locus_tag="OPY25_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HCS0929350.1"
                     /translation="MSGINLNKKLWRMPQKGMVRGVCAGIADYLDVPVKLVRILVVLS
                     IFFGLAFFTVVAYIVLSFVLDPMPDNLAAGKPQPTSGELLDTVDRELAAGEKRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            5171..5389
                     /gene="pspD"
                     /locus_tag="OPY25_003856"
     CDS             5171..5389
                     /gene="pspD"
                     /locus_tag="OPY25_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HCS0929351.1"
                     /translation="MNTRWQRAGQKVKPGFKIAGKLVLLTALRYGPAGVAGWAVKSVA
                     RRPLKMLLAFALEPVLRKAANKISQRYK"
     gene            5465..5779
                     /gene="pspE"
                     /locus_tag="OPY25_003857"
     CDS             5465..5779
                     /gene="pspE"
                     /locus_tag="OPY25_003857"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HCS0929352.1"
                     /translation="MLKKGIFALALFVAMPLYAAEYWIDVRIPEQYQREHIQGAINIP
                     LKEIKSHIETVVPDRNDTVKLYCNSGRQSGMAKQMLLDMGYTHAMNMGGISRLDMPKV
                     KK"
     gene            5928..7325
                     /locus_tag="OPY25_003858"
     CDS             5928..7325
                     /locus_tag="OPY25_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HCS0929353.1"
                     /translation="MKRLKTELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NVHAGARLPLLSAVREERLLGVKRVPQRDFGIPRFTYDEGILQLYGNPPAWPTPTRGV
                     SEIRLALRYRSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMNGLL
                     QGQRAEWAAKWRQLCDGLDPLAPADENRLAEIAAAWTDYLHQCKSQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDAFGESKLAQADKQTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTLDQHANMVALLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGVIEVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPSRLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            7322..8383
                     /locus_tag="OPY25_003859"
     CDS             7322..8383
                     /locus_tag="OPY25_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HCS0929354.1"
                     /translation="MSEPLKPRIDFAEPLKEEPTSAFKAQQTFSEAESHTFAPAAIDE
                     RPEDEGVAEAAVDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIVGAGVGSVVTEWWRLWRLRQRAHERDEARELLHSHSVVKGRAFCEKLAQ
                     QAGIDQSHPALQRWYAAIHETQNDREIVGLYAHLVQPVLDAQARREISRFAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFRLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWADNDKPRLGDFRR
                     QLIGQLKETLQKSKSSPEK"
     gene            8531..>10071
                     /gene="tyrR"
                     /locus_tag="OPY25_003860"
     CDS             8531..>10071
                     /gene="tyrR"
                     /locus_tag="OPY25_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HCS0929355.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFA
                     ELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHLALSALLEALPEPVLSLDMKSKV
                     EMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLME
                     ITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVE
                     QARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVR
                     VICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKGEE"
BASE COUNT         2423 a         2506 c         2824 g         2318 t
ORIGIN      
        1 tagccatagc acccaaaata tcggaaatca cattgaccac aataaccagc gacccaatga
       61 ccatcacgcc agcggaaata gcggcatagt cctgctgacg aatggcgtga attaaccatc
      121 gtcccagccc tggccagctg aaaaccattt cggtaatcat cgccagcgtt aacatggttg
      181 aaaactgcag accaagacgg ggaatgaccg gcggcagcgc attatgcaac acgtgacggc
      241 gtaaaatcgt aaagcgcgac aagccgcgcg tggccgccgc tttaacgtag ttctgatcgt
      301 agacctcaat agtgctgatt cgcatcaggc ggatcacctc tgtggtcggc gcgacggaaa
      361 gcgtgagcac cggtaaaacc atatgtcgta tggcgctcat taccatttca tcacgccacg
      421 gcgaatctga aatccaggcg tcaatgatgg cgaaaccggt aaccggttta acttcataaa
      481 gcaggtcaaa tcgcccggat accggcagcc accccagtgt gagcgaaaag aacagtgtga
      541 gcagaagcgc cagccagaaa accggaattg agaaacctaa tagcgccagc gcgctgataa
      601 aacgatccgg ccatttgcta cgcgtcacgc cagccagcat cccgaccggg atgccgacca
      661 tcagcgcaaa accaaaggcg agaatgcaca gctccatcgt ggcgggaaac acctctttaa
      721 gctgttcgga gatcagctgg ccgttaatgc tggacacgcc aaagtcccag tgcagcagac
      781 cgttgaacca gaaaacccag gcattccata atgatgcgcc ttgtagcggc gcgtgcggcg
      841 taaaatagct caggctaaag ccgataaagg tcaggaagaa tagcgtcacc agcaacagca
      901 ataaccgacg cagggtgaag ataatcatgg ttttttcacc tcttcgtgtt tttcgcggga
      961 gacgccggca aaagacgcat tgccgaacgg gcttaacacc agtcctttaa tatcgtagcg
     1021 gtaagcctgt aagcgtagtg atgatgccag cggcagtatc ggcagctctt tctccaggat
     1081 attctgcgct tcgtcatacg cttctatgcg cgaagccaac tgctgcgacg acagtgcctt
     1141 acgcagcacg ctgtcaaatt cagggttaca ccagtgggcg aaattggttt gcgaattgat
     1201 ggccgcacag cttaacagcg gtctgaaaaa gctatccgga tcgttgctgt ccgtggccca
     1261 gccggataag gtcagatcgt gattcatatc catcaggcgc gcctcctgaa aacgaccttc
     1321 aaccggcaca atgaccactt ttacgccaac ttgcgccata tccgcctgaa taagctccgc
     1381 cgtttttagc gggcttgggt tccaggcctg agaactggtc ggcacccaga gatgcagcgt
     1441 aagattctca atgcccagcg cttttagttg ttcgcgcgat ttttgcggat tgtactccgt
     1501 aattttggca tcgttatcgt aagcccatga ggctctcggt aaaatggagg ctgcggtttc
     1561 cgccgtgccg taataaatcg actgcatcag gcgctggttg ttgatcgata aggccagcgc
     1621 atggcgcact gcgggattat tcaacggcgg cttgtcggtg ttaaaggcca gataggcgat
     1681 attcatcccc gggcgcaacg tcagacgcaa acgcggatcg tcgcgtaaaa tagttagctg
     1741 gctggcggcg ggccaggcca gaacatcgca ttcaccggtc agtaatttcg ataaacgccc
     1801 aatacccccg gagcctaaat ccaccaccac ttgcggcatt agcggtttgc cgcgccaaaa
     1861 cccatcgtgg cgctggagac gaataaactg cccggcacgg tactccgaaa gctggaaagg
     1921 cccggtgccg accggttgcc gatcaagcag ttcctgacga tcttttcggc taagctgcgc
     1981 ggcgtactca gcagacatga cggaagcgta gtgcgtggcc agatgccata aaaaggaggc
     2041 gtctggctgc gtcaggcgaa actcaacggt gttattgtcc agcttacgca cgctttttac
     2101 attgtcggcg aactgtaggc tatcaaagta ggggaagcta ctgccgttga tgttatgcca
     2161 cggatgtcga cgatcgaaaa tccgctgaaa ggtaaagacg acatcatcag cattgagttt
     2221 tcgggtcggc gtaaaccagg cggttttttg aaaggaaacg tcgcggcgca ggtgaaaatg
     2281 gtacgttgcc ccgttatcca gcacttccca gctttctgcc agctctggga ctaaacgata
     2341 agtataggga tcgacatcca acaggcggtc atataactgg gcggccaggg tatcgacgat
     2401 gaggccgcta ctcgcttttt gcggattaaa ggtgttgacc tgcccgctga cacaatacac
     2461 aaagccgcta tcgcgaatat ctgcactcgc agtttgttcg ggcgcagtcg cagccgtagc
     2521 ctgactactc agtagacccg ctatcacgat cagagatgat aaaaccaggc gcataatagt
     2581 taagtttttg aagttcaatt tgcaaagtgt atcgcacttc ggcccgccac gtaaaaatgt
     2641 cggtggataa ctggcgtaaa tgtcgtcaat tagccggaga aatagctaaa gctgatgctt
     2701 tttaagcaag gcgcgaaact ggtggtaggt gagcgccagc aaatcggcgg ctcgtttctg
     2761 gttaaatttc gcctgctgta agctacgttg cagcagcgct ttttcctgtt gcagttgaaa
     2821 ctcccgcaag ttgagcggca ggtcaggcgt ggcggatgcc gctggcaggg cgggcgcggg
     2881 cggttcggcg ggatagcgtt gaaaaggatc gataacaatt tcatccaaag gatgttcgct
     2941 gctgccgtgg cgatacactg aacgttcgac tacgtttttc agctcgcgga cattacccgg
     3001 ccaggcgtaa tgcaacaacg tttcttttgc ccgatcggta aaaccaggaa ataagggcag
     3061 acgtagctca cgacacatct gaatagcaaa atgctcggcc atcagcatga tatcgctctg
     3121 gcgttcgcgc agcggcggca gttgtacaac gtcaaaagcc agcctgtcga gcagatcggc
     3181 acgaaatgtc ccttccttca ccatggcggg taaatcggca ttagtggcgc atactaatcg
     3241 cacattaacc tgtaacggtt ggctgccgcc gacgcgctct agctcgccat attcaatcac
     3301 ccgcagtagc ttttcctgta ccagcattgg cgctgtcgcc agttcatcca aaaacagcgt
     3361 gccaccatcg gcgcgttcaa aacgaccggg atggcgtttt tgcgccccgg taaaagcgcc
     3421 cgcttcatgg ccaaacagtt cggagtccag cagattttcg ttaagcgccg cgcagttaag
     3481 cgagataagc ggcccctgcc agcgtgaaga gagatagtgc aggcgattgg cgataagttc
     3541 tttacccgta ccgcgttcgc caataatcag cactggctta tccagcggcg cgagccggga
     3601 gacttgttcc agtacttcaa gaaaacagtt tgcctcgccg agcaggttat ctttaaattc
     3661 agccatgatg aaaatcgcca cttgttagtg tttttcacca ctttatcctt tttggctggc
     3721 gaggtaaaac gaaataattc cttaactatc aataatataa aaagttggca cgcaaattgt
     3781 attaatcatg tagcagggca tcgcccgtta tcagaacatt atgtgaggat tgaattatgg
     3841 gtattttttc tcgttttgcc gacatcgtga acgccaatat caatgcgttg ttggaaaaag
     3901 cggaagatcc gcagaagctg gtgcgcctga tgattcagga gatggaagat acgctagtgg
     3961 aggttcgctc gaactccgcg cgagctttag cggaaaagaa acagttatcc cgtcgtattg
     4021 aacaggctac ggctcagcag accgagtggc aggaaaaagc ggaactggct ctgcgcaaag
     4081 ataaagacga tctggcgcgc gccgcattga ttgaaaaaca aaagctgacc gatttaattg
     4141 ctacgcttga acaggaagtc acgctggtgg atgacacgct ggcgcgcatg aagaaagaga
     4201 ttggcgagct ggaaaacaaa ctcagcgaaa cacgcgctcg ccagcaggcg ctgatgctgc
     4261 gtcatcaggc ggcaagttct tcccgcgatg tccgtcgtca gcttgacagc ggcaaactgg
     4321 atgaagccat ggcgcggttt gaatcctttg aacgtcgtat cgatcaaatg gaagcggaag
     4381 cggaaagcca tcgttttggt aagcagcaat cgctggacca acagtttgcc aacctgaaag
     4441 ccgatgatga aatcagcgag cagctggcgc agttgaaagc caaaatgaag caagataatc
     4501 aataatgaca atggcggcgc cggtacgcgc cgtcgctcat cagctttagg tgtaaggaga
     4561 acgcatgagc gcgctatttc tggccatccc gttaaccatt tttgtgttgt ttgtgttacc
     4621 gatttggctg tggctgcatt acagcaaccg cgccggtcgg ggagaactgt cgcaaagcga
     4681 gcagcaacgc ttactgcaac tcacagacga cgcgcaacgt atgcgcgagc gcattcaggc
     4741 gctggaagat attcttgatg cagagcatcc gaactggaga gagcgctaat gagtggaatc
     4801 aatctgaata aaaaactatg gcgtatgccg caaaagggca tggtgcgtgg cgtttgcgcc
     4861 gggatcgccg actaccttga tgtaccggta aaactggtgc gtattctggt cgtgctgtcg
     4921 attttctttg ggctggcgtt ttttaccgta gtggcctata tcgtcctgtc ttttgtactg
     4981 gaccctatgc cggataatct ggccgcaggg aaaccgcagc cgaccagcgg cgaactgctg
     5041 gataccgtag acagagagct tgccgcaggc gaaaagcgtt tgcgagaaat ggaacgctac
     5101 gtcacgtcag atacgttcac actgcgtagt cgtttccgtc aactgtaact gatatatcgg
     5161 gaaggtgaag atgaatactc gctggcaacg cgccgggcag aaggtgaagc ccggcttcaa
     5221 aatagcaggt aagctggttc tgttgaccgc gttacgctac gggcctgccg gcgtggcggg
     5281 atgggcggta aaatccgtcg cccgtcgtcc gctaaaaatg ttgctggcgt ttgcgctgga
     5341 gccagtactt cgtaaggcgg cgaataaaat ttcgcagcgt tacaaatagc gagtctggtc
     5401 ataatatttc gttaagctct ggcgtatagt gtgtgcgaaa tacattacgt gtcaggacgg
     5461 gagtatgttg aaaaaaggaa tatttgcgtt agcgttattc gtagccatgc cgctttatgc
     5521 cgcagaatac tggatagatg tccgcattcc ggaacaatat caacgagagc atattcaggg
     5581 cgcgattaat atcccattga aggagattaa atctcatatc gaaacggtag ttccagacag
     5641 gaacgatacg gtaaagttat attgcaactc cgggcgacag tcgggcatgg caaaacaaat
     5701 gttgcttgat atggggtata cgcacgcgat gaatatgggc ggcatcagtc gtcttgatat
     5761 gccgaaagta aaaaaataga taatctattg ctcaatactc atactaaccg cggcgcttaa
     5821 tgcgccgttg ttgatctctc cgggtagttg ataataacgt ttttgcacat atctataacg
     5881 caggctcgtt attatttttt cttctcttca ggctcaacag gatgtcaatg aagcgactta
     5941 aaactgaact caacgcgctg gtcaatcgtg gggtagacag gcatttgcgt cttgccgtaa
     6001 ccgggttgag ccgcagcggt aaaacagcgt ttatcacggc gatggttaac cagttgctta
     6061 atgtccacgc gggcgcgcgc ttaccgttgc tcagcgcggt acgcgaagaa cgcctgcttg
     6121 gcgtaaagcg cgtgcctcaa cgtgattttg gtattccccg ttttacctac gacgagggga
     6181 tacttcagct ttatggcaat cctcccgcct ggcccacacc gacgcgcggc gtcagtgaga
     6241 ttcggctggc gttgcgctat cgctcaaacg actcgctgct gcgccatttt aaagatacct
     6301 cgacattgta tctggagatt gtggactatc caggggaatg gttactcgat ctgcccatgc
     6361 tggctcagga ttatttaagc tggtcccgtc agatgaacgg cttgttacaa gggcaacgcg
     6421 ctgagtgggc cgcaaaatgg cggcaacttt gcgacgggct cgatccgctg gcgcccgccg
     6481 atgaaaatcg gctggcggag attgccgccg cctggacgga ttatttgcat cagtgtaaat
     6541 cgcagggatt gcattttatt cagcctggac ggtttgtttt gccgggcgat atggcgggcg
     6601 cgccagcgtt gcagtttttc ccgtggccgg atgtggacgc cttcggcgag tcaaaactgg
     6661 cgcaggcgga taaacagacc aacgctggaa tgctgcgcga acgctttaac tactattgcg
     6721 aaaaggtggt caaagggttc tacaaaaatc attttctacg ctttgatcgc cagattgtgc
     6781 tggtcgactg tctgcaaccg cttaatagcg ggccgcaggc gtttaatgat atgcgtctcg
     6841 ctttaacgca gctgatgcaa agttttcact atggtcagcg aactctgttt cgccgcttgt
     6901 tttcgccggt gattgataaa ttgctgttcg ccgcgacgaa agccgaccat gtcaccctcg
     6961 accaacatgc caatatggtg gccttgctcc agcagcttat tcaggatgcc tggcaaaatg
     7021 ccgcgtttga aggcattagt atggattgcc tggggctggc gtcggtacag gcgaccacca
     7081 gcggcgtgat tgaggtcaac ggtgaaaaaa tcccggcttt acgtggaaac cgtttgagtg
     7141 acggcgcgcc gttaaccgtg taccccggcg aagtgccttc gcgtttgccg ggacaagcgt
     7201 tttgggataa gcagggcttt cagttcgaag cctttcgtcc gcaggtaatg gatgttgata
     7261 aaccattacc acacattcgt ctggacgctg cgctggagtt tttaatagga gataagctgc
     7321 gatgagcgaa ccgttaaaac cgcgtattga ttttgcagaa ccgctaaagg aggaacctac
     7381 atcggccttc aaagcgcagc aaactttcag cgaagcggag tcgcatacat ttgcgcctgc
     7441 ggctatcgat gagcgcccgg aagacgaagg cgtggcagaa gcggcggtcg atgccgcgct
     7501 gcgccccaaa cgcagcctgt ggcgtaaaat ggtgatggga gggctggcgc tgtttggcgc
     7561 gagcgtggtc gggcaaggcg tacagtggac aatgaatgcc tggcaaactc aggactgggt
     7621 cgctttaggc ggctgtgccg caggcgcgct gatcgttggc gctggcgtgg gatcggtggt
     7681 cacggagtgg tggcgattat ggcgcttgcg ccagcgggcg catgagcgcg atgaggcgcg
     7741 tgaactgtta catagccata gcgtcgtgaa aggtcgcgca ttttgcgaaa aactggcgca
     7801 gcaggcgggg attgatcaat cacatccggc attacaacgt tggtatgccg ctattcacga
     7861 aacgcaaaac gacagggaaa tcgtcggctt gtatgcgcat ctggtacagc cggtacttga
     7921 cgcgcaggcg cgacgtgaga ttagccgttt cgccgcggaa tcgactctga tgatcgctgt
     7981 cagtccgtta gcgttggtgg atatggcgtt tattgcctgg cgtaatttac gcctgattaa
     8041 ccgcatcgca acgctgtatg gcattgaact tggttattac agccgccttc gtctgttccg
     8101 tctggtgttg ctgaatatcg cgtttgcggg ggccagtgag ctggtgcgtg aagtcggtat
     8161 ggactggatg tctcaggatc tggccgcacg cctgtctacg cgcgcggcgc aggggattgg
     8221 cgcaggcctc cttaccgctc gactgggaat aaaagcgatg gagctatgtc gaccattgcc
     8281 gtgggccgat aacgataaac cacgtctcgg tgattttcgt cgtcagctta tcggtcagct
     8341 aaaagagacg ctgcaaaaga gtaagtcgtc gcctgagaaa tgaccttcca cagggcgctg
     8401 attgcctggc tttacgccgc agcgcccgtt tttccgccat gctgtcaata tttgttgaca
     8461 gaatccttcc tgccagccga atagtggctt atcatctatt taatggttca ttattcaggt
     8521 gaaggttccc atgcgtctgg aagtcttttg tgaagaccga cttggtctga cccgcgaatt
     8581 acttgattta ctggtgttac gtagcattga tttacgcgga atcgagattg atcccattgg
     8641 gcgaatttat cttaattttg ctgagctgga attcaccgac ttcagcagcc tgatggccga
     8701 aatccgccgt atttccggcg taacggatgt ccgtaccgtt ccctggatgc cgtccgaacg
     8761 tgaacatctg gccctgagcg cgctgcttga ggcgttgccg gagccggtgc tctcattgga
     8821 tatgaagagt aaagtggaga tggcgaaccc ggcgagttgt caactttttg cccagagcca
     8881 ggagcgaatg cggcaccata ccgccgcaca attaatcaac ggcttcaatt ttcagcgctg
     8941 gctggacggt aacccgcaaa gctcccataa cgaacatgtc gtgatcaacg ggcaaaactt
     9001 cctgatggag attacgccgg tacatttaca aaacgaaaat gacgaatacg tgttgaccgg
     9061 ggcggtcgtg atgttgcgtt ccacgattcg tatgggacag cagctacaga atttgtccac
     9121 gcaggatctg agcgcgttta gtcagattat tgccgtgagc gcaaagatga agcacgtcgt
     9181 tgagcaggcg cgcaaactgg cgatgctcag cgcgccgctg ctgattaccg gcgatacggg
     9241 aaccggcaaa gatcttttcg cctatgcctg tcatcaggca agccctcgtt cagcgaaacc
     9301 gtatctggcg ctcaactgcg cttcaatccc ggaagatgcg gtagaaagcg aactatttgg
     9361 ccatgcgccg gaaggtaaaa aaggcttttt tgaacaggcg aatggcggct cggtgctgct
     9421 ggatgaaatt ggcgaaatgt caccgcgtat gcaggcgaag ctgctgcgtt ttctcaatga
     9481 tggtacgttc cgtcgtgtcg gcgaagatca cgaaattcat gttgatgtcc gcgttatctg
     9541 cgccacgcag aaaaatctgg tggagctggt gcaaaaagga ctgttccgcg aagatctcta
     9601 ttatcgactt aacgttctga cgcttaattt gccgccgttg cgcgattgtc cgcaggatat
     9661 tatgccgttg accgaactgt tcgtggcgcg ttttgccgac gaacagggcg ttccacgacc
     9721 gaaactgtct gccgatctga gtacggtcct cactcgttac ggctggccgg gtaacgttcg
     9781 ccagcttaaa aatgcgattt atcgggcgct gacgcaactg gaagggtatg agctgcgtcc
     9841 gcaggacatc ctgttgcctg actacgatgc cgcgacggtg gcagtcggcg aggatgcgat
     9901 ggaaggttcg ctggatgaca ttaccagtcg tttcgaacgt tctgtcctta ctcagcttta
     9961 tcgtagctat ccgagtacgc gtaaactggc gaaacggttg ggggtatcgc ataccgcgat
    10021 tgccaataag ctgcgtgaat atggtctgag ccagaagaag ggtgaagagt a
//
LOCUS       DAJVKX010000148         9956 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.148, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000148 DAJVKX010000000
VERSION     DAJVKX010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9956
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.148"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            169..750
                     /locus_tag="OPY25_003861"
     CDS             169..750
                     /locus_tag="OPY25_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0929356.1"
                     /translation="MRNKIILAMAAAGMMYGASVYAVDPPTAGPFGSGKITFTGTITN
                     SPCDIAPGDDAITVPFGQISYRKLNTADATTDSKPFTIHLQNCAFDPNIPDTAGSAGK
                     MSKVTVSFSGGANVAKKAYTTSGSAQHVGVQLLKSDNTAIIEPNTQMPEDDAQQLQAG
                     NNELNFYARLIALDNGVTPGDFTASVTYTLKYL"
     gene            870..3359
                     /gene="stdB"
                     /locus_tag="OPY25_003862"
     CDS             870..3359
                     /gene="stdB"
                     /locus_tag="OPY25_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein StdB"
                     /protein_id="HCS0929357.1"
                     /translation="MKITRLAILITLTFSVLKSQATEFNASLLDSGNLSNVDLTAFSR
                     EGYVAPGNYILDIWLNDQPVREQYPVRVVPVAGRDAVVICVTTDMVAMLGLKDKIIHG
                     LKPVTGIPDGQCLELRSADSQVRYSAENQRLTFIIPQAWMRYQDPDWVPPSRWSDGVT
                     AGLLDYSLMVNRYMPQQGETSTSYSLYGTAGFNLGAWRLRSDYQYSRFDSGQGASQSD
                     FYLPQTYLFRALPALRSKLTLGQTYLSSAIFDSFRFAGLTLASDERMLPPSLQGYAPK
                     ISGIANSNAQVTVSQNGRILYQTRVSPGPFELPDLSQNISGNLDVSVRESDGSVRTWQ
                     VNTASVPFMARQGQVRYKVAAGRPLYGGTHNNSTASPDFLLGEATWGAFNNTSLYGGL
                     IASTGDYQSAALGIGQNMGLLGALSADVTRSDARLPHGQKQSGYSYRINYAKTFDKTG
                     STLAFVGYRFSDRHFLSMPEYLQRRATDGGDAWHEKQSYTVTYSQSVPVLNMSAALSV
                     SRLNYWNAQSNNNYMLSFNKVFSLGELQGLSASVSFARNQYTGGGSQNQVYATISIPW
                     GDSRQVSYSVQKDNQGGLQQTVNYSDFHNPDTTWNISAGHNRYDTGSNSSFSGSVQSR
                     LPWGQAAADATLQPGQYRSLGLSWYGSVTATAHGAAFSQSMAGNEPRMMIDTGDVAGV
                     PVNGNSGVTNRFGVGVVSAGSSYRRSDISVDVAALPEDVDVSSSVISQVLTEGAVGYR
                     KIDASQGEQVLGHIRLADGASPPFGALVVSGKTGRTAGMVGDDGLAYLTGLSGEDRRT
                     LNVPWDGRVQCRLTLPETVTLSRGPLLLPCR"
     gene            3400..4143
                     /locus_tag="OPY25_003863"
     CDS             3400..4143
                     /locus_tag="OPY25_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HCS0929358.1"
                     /translation="MKNSRRSRVILLALAAAWSQYSPAAVNVDRTRIIMDAPQKTVAI
                     TLNNDDKTTPFLAQSWVTDADGVRTDALIALPPLQRIDAGQKSQVRITQVRGLTDKLP
                     QDRETLFWFNVRGVPPKSEDDNVLQLAMQSQLKLFYRPKAIIRSSSDQPERKLTAERN
                     AGHLTLRNPTPYYITVAWLGADRSHRLSGFREGVMVPPLGSLPLKAVLPAETRTLWVG
                     YIDDYGGLQMNRYTCDALNCAFKDAGVTS"
     gene            4140..5216
                     /locus_tag="OPY25_003864"
     CDS             4140..5216
                     /locus_tag="OPY25_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929359.1"
                     /translation="MTEWIFNLKTKLTVLVMMLCSLCVTKVYAVEPGINECVVTSGQN
                     INLRSINLTTDDFKPGPDSVIYSINQDAVFKCSMGYGTQFPQLVFNQGYFSKFTQTLD
                     AMGLGFRMSVKETENVSNVVSFSWDEIKSTQSGNELRKEFGTKLPVGTTERKVRITLD
                     FLYTKAYSESSAVTAFTGISNVLNIVPFPYSLRQNGFVLSGFNVRILRNGLGKVDIVP
                     LQVNFGHIYTTYEPSQTRQANFTVIARQVLRPAMGQEFAIPLAITFGKGALTQDTGQT
                     LNLVSLDGPNKGQPNGLRLSIKDDKGKEITFDKQEVLGDITITGTVTGNVSKVYTAVI
                     TPTLGGSVKTGKFSAAILVTVTYN"
     gene            5361..5873
                     /locus_tag="OPY25_003865"
     CDS             5361..5873
                     /locus_tag="OPY25_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001727965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiF/GrlA family transcriptional regulator"
                     /protein_id="HCS0929360.1"
                     /translation="MCPDNTHAKKQYLIPGNDIHYPGQTNHDACFIPVSVRQYAGEPL
                     YIIVAHWCLLQQNWVQRNQIAEAFHITARRASYLIAYLRSKTSRVVSICRHQTLPNKA
                     RRYEIYVIRVLDSPTPSTRREKAGPPPVSKRRVGNGDRSMANELWNRLCSNRNAGKIL
                     KKREDEDDRT"
     gene            5860..6618
                     /locus_tag="OPY25_003866"
     CDS             5860..6618
                     /locus_tag="OPY25_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0929361.1"
                     /translation="MTEHNRIPARQIIVYGDCWPVTIAVAHLVRRFLPGCNCETAYRL
                     PVLLQQLRRKPEAILILCLRPREHLFLFYSLRQILPDYPVMIISDELFFSDRVVLKVY
                     GGIPALLEQELAEILIRWRRDEQWAGGARLRRTGGLDAFLLSPDPVTGFLEVPPIFNN
                     PKRLMNYMDQLMHREILACGVSLAQLRLLQEVYRGRGRLSALCGRLNTQEKQIWQDKY
                     RLLVKLGMRNRLRELLFGTRFCKSLQRTPFIAPQ"
     gene            complement(6828..7682)
                     /locus_tag="OPY25_003867"
                     /pseudo
     CDS             complement(6828..7682)
                     /locus_tag="OPY25_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461941.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
     gene            7804..8076
                     /gene="rcnR"
                     /locus_tag="OPY25_003868"
     CDS             7804..8076
                     /gene="rcnR"
                     /locus_tag="OPY25_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HCS0929362.1"
                     /translation="MSHTIRDKQKLKARTSKIQGQVIALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQSDEARREEDLDVILKVLDSYIK"
     gene            complement(8107..9336)
                     /locus_tag="OPY25_003869"
     CDS             complement(8107..9336)
                     /locus_tag="OPY25_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HCS0929363.1"
                     /translation="MSKIWSKDETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGSIITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHIQIDIRIRMAVSFGVVLILNMIFLMGRHATLRVMGFLVFPL
                     IAYFLFLSLYLTGSWQPSLLTGQMSLDSHTLHQVWISIPVMVFAFSHTPIISTFAIDR
                     RENFGDQAMDKCKKIMKVAYLIICLSVLFFVFSCLLSIPPSYIEDARNEGVTILSALS
                     MMPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEIVRTTLQQVGVKKSRAFNRA
                     LSIMLVSGITFIICCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPYRSIGN
                     FITLVVGLLCVSVMFFG"
     gene            complement(9478..9933)
                     /locus_tag="OPY25_003870"
     CDS             complement(9478..9933)
                     /locus_tag="OPY25_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/biocide efflux PACE transporter"
                     /protein_id="HCS0929364.1"
                     /translation="MQHDAIQRRSLPERIFHAVCFEGIATAILAPTTAWLMQRSVLEM
                     GGLTILLATTAMIWNIIYNALFDRLWPAHQVRRTAKVRALHALGFESGFIVIGVSIVA
                     WVLNVSLLQAFTLEIGFFLFFLPYTMLYNWAYDVLRQRIVTRRQQRVSA"
BASE COUNT         2572 a         2533 c         2665 g         2186 t
ORIGIN      
        1 taggcattag ctgaaatcaa tatttttcga tggaaagttc aggtgcttcg tttaacaccc
       61 ggcgtttatt attcatgcga atcttttctg aacgctttca ttaataccct cagatttgtt
      121 ttcagccttt gcaaaataat tctcattcac ccaaaggaca tattatctat gcgtaataaa
      181 ataatacttg ccatggcggc tgccggtatg atgtatggcg cttctgtata tgcagtcgat
      241 ccaccaacag caggcccgtt cggctcaggt aaaattacct ttactggtac catcaccaac
      301 tccccctgtg atatcgcacc gggcgacgat gcgatcaccg ttccatttgg acagatttct
      361 taccgtaaac tgaataccgc cgatgcaacc acggactcaa aaccgttcac cattcatctg
      421 cagaactgtg ctttcgatcc gaatatcccg gacacagctg gctccgcagg gaaaatgtcc
      481 aaagtgaccg tctctttctc tggcggagcc aatgtcgcga aaaaggctta caccaccagc
      541 ggcagcgcac agcatgttgg tgtccagcta ctgaagagtg acaacaccgc aattatcgag
      601 cccaacaccc agatgccgga ggacgacgct cagcaactgc aggccggaaa caacgaactc
      661 aacttctatg cccggctaat agcactggat aatggcgtca cgcccggtga cttcaccgca
      721 tctgtcacct acactctgaa atacctgtga ttttacgcgg taaataacga cagggagaag
      781 ccgtccacgg aggggttcgg acggctttta tatctgacca tgcctgcggg ctgtctgtta
      841 cacggacgac aacacgaaag cgccatgcca tgaaaattac ccggcttgcc attctgatta
      901 ccctgacatt ttccgtcctg aagtcgcagg ccacggagtt caatgccagc ctgctggaca
      961 gcgggaacct gtctaacgtg gacctcacgg ccttcagccg cgaggggtat gtggcgcccg
     1021 gtaactatat tctcgatatc tggctcaatg accagccggt acgggaacag tatccagtca
     1081 gggttgtacc ggttgccgga cgcgatgcgg tcgtcatctg tgtgacaaca gacatggtgg
     1141 ccatgctggg tcttaaggat aagattattc atggcctgaa acccgttacc ggtatcccgg
     1201 acgggcaatg ccttgagctg cgctccgctg acagtcaggt acggtacagc gctgaaaatc
     1261 agcgtctgac cttcattatt ccccaggcct ggatgcgtta tcaggacccg gactgggtgc
     1321 ccccttcacg ctggagcgac ggcgtcaccg ctggcctgct tgattacagc ctgatggtca
     1381 accgctatat gccgcagcag ggggaaacct ctaccagcta cagcctctac ggcaccgccg
     1441 ggtttaatct cggcgcctgg cggttgcgga gcgattacca gtacagccgt tttgacagtg
     1501 ggcagggcgc atcacagtcc gatttttatc tgccgcagac gtatctgttc cgtgccctgc
     1561 cagcactgcg ctcaaaactg acgctcggac agacgtacct cagctccgct atttttgact
     1621 ccttccgctt tgctgggctc actttggcca gcgatgagcg catgctgccg ccctctcttc
     1681 aggggtatgc cccgaaaatt agcggcattg cgaacagtaa tgcacaggtc accgtcagcc
     1741 agaatggtcg cattctgtac cagacccggg tgtcaccggg gccttttgag cttcccgacc
     1801 tgagccagaa tatcagcggc aacctggatg tcagcgtccg ggaaagcgac ggcagcgtcc
     1861 ggacctggca ggtcaacacg gctagcgtcc cctttatggc acgccaggga caggttcgct
     1921 ataaggtggc cgccggacgt ccgctgtacg gcggtacgca taacaacagc acggccagcc
     1981 ctgactttct gctcggggag gccacctggg gagcatttaa caacacgtcg ctgtatggcg
     2041 gcctcattgc ctccaccggc gactaccagt ccgcggcgct cgggatcggc cagaatatgg
     2101 ggctgctggg cgctctgtct gcggacgtca cccgctcaga tgcgcggttg ccgcacgggc
     2161 agaagcagtc cggttacagc taccgtatca actatgccaa aacgtttgat aaaaccggca
     2221 gtaccctggc gttcgtcgga taccgcttct cggaccgcca ttttctgtcc atgccggagt
     2281 acctgcagcg tcgggccacc gacggcggcg atgcatggca tgaaaaacag agctacaccg
     2341 tgacttatag ccagtccgtt ccggtactca acatgagcgc ggccctctcg gtaagccggc
     2401 tcaattactg gaatgcgcag tccaacaata actacatgct cagcttcaac aaagtgttca
     2461 gtctcggcga gcttcagggg ctctcggcct cggtgtcgtt tgcccgtaac cagtacaccg
     2521 gcgggggcag ccagaatcag gtctacgcca ccatcagtat cccgtggggc gacagccgcc
     2581 aggtgagcta cagcgtgcag aaggataacc agggcggcct gcagcagacc gtgaattaca
     2641 gcgatttcca taacccggac accacatgga acatcagcgc cggtcataac cgctatgaca
     2701 ccggcagtaa cagcagcttc agcggcagcg tgcagagccg tctgccgtgg ggccaggcgg
     2761 cagcggacgc caccctgcag cccggacagt accgcagcct gggcctgagc tggtacggct
     2821 cggtgaccgc caccgcccac ggcgccgcct tcagccagtc gatggccggg aatgagcctc
     2881 gcatgatgat agataccgga gacgtggccg gtgtaccggt gaacggcaac agcggggtga
     2941 ccaaccgctt cggggtgggc gtggtgagcg ccggcagcag ctatcggcgc agcgatattt
     3001 cggttgatgt ggccgccctg ccagaggacg tggacgttag cagctccgtc atcagccagg
     3061 tgctgacgga gggcgcggtg ggctaccgga agattgacgc cagccagggg gagcaggtgc
     3121 tcggtcatat ccggctggct gatggcgcca gtccaccgtt tggcgccctg gtggtgtccg
     3181 gaaaaaccgg cagaaccgcg gggatggtcg gggatgacgg tctggcctac ctgaccggac
     3241 tcagcgggga agaccgccgg accctgaacg tgccctggga tggccgggtg cagtgcagac
     3301 tcaccctgcc ggaaacggtg acactcagtc gggggccgct gttactgccc tgcagataaa
     3361 aatatccctg tcacagagca ggactaacgg agaaaacagg tgaaaaacag cagaagaagc
     3421 cgtgtgattt tactcgcact ggcggcagca tggagccagt acagcccggc agccgtcaat
     3481 gtcgaccgga cccgtattat catggatgca ccgcagaaaa cggtggccat cacgctgaat
     3541 aacgatgaca aaaccacgcc gttcctggcg cagtcctggg tgacggacgc tgacggggtg
     3601 agaacggatg cgctgatagc gctgccaccg ctgcagcgta ttgatgccgg acagaaatcc
     3661 caggtccgta tcacccaggt tcgcgggctg acagacaagc tccctcagga cagggaaacg
     3721 ctgttctggt ttaacgtgcg gggcgttccc ccgaagtcag aagacgacaa cgtcctgcaa
     3781 ctggccatgc agagccagct gaaactgttt taccgtccga aagccattat cagaagcagc
     3841 agtgaccagc cggaaagaaa gctgactgct gagcggaatg cgggacatct gaccctcaga
     3901 aacccgacgc cgtactacat cactgtggcg tggctgggag cagaccgcag ccacaggctc
     3961 agcggtttcc gcgagggcgt gatggtgccg cccctgggga gcctgccctt aaaggctgtt
     4021 ctgccggcag aaacccggac gctgtgggtg gggtatatag atgattatgg tggactgcag
     4081 atgaaccgct acacctgtga tgccctgaac tgcgcgttta aggacgcagg ggtgacatca
     4141 tgacagaatg gatttttaat ctgaaaacaa aactgaccgt gctggtgatg atgttgtgtt
     4201 ctttatgtgt gactaaagtg tatgcggttg agccaggtat aaatgaatgt gtagtcactt
     4261 ctggtcagaa tattaattta agaagtataa atttgacaac cgatgatttt aaacctggcc
     4321 cggattcggt tatctattca atcaatcagg atgcagtttt caaatgttca atgggatatg
     4381 gcacgcaatt tccacagctg gtatttaatc agggctactt cagtaaattt acccagacac
     4441 tagatgcgat gggacttgga ttcagaatgt ccgttaaaga aacagaaaat gtttcaaatg
     4501 ttgtttcgtt ctcctgggat gaaataaaga gcactcagtc aggaaatgag ttacgaaaag
     4561 agtttggcac aaaactacct gttggaacta cagagcgaaa agtaaggata acactggatt
     4621 tcttatatac aaaagcatat tcagagagta gtgcagttac agcttttacg gggataagta
     4681 atgttttaaa tattgtacct tttccttatt ctttgagaca aaacggattt gttttatctg
     4741 gttttaatgt gagaattctc agaaacggat tgggtaaagt tgacattgtt ccattacagg
     4801 tcaactttgg gcatatttat acgacttatg aaccttcaca gaccagacag gcaaatttta
     4861 cagtgatcgc caggcaggtt ttacgaccgg ctatgggaca ggaattcgcg atcccgctgg
     4921 ccatcacctt cgggaaaggt gcgctgacac aggataccgg gcaaactctg aatcttgtca
     4981 gtctggatgg ccccaacaaa ggtcagccta atggactccg gctttcaata aaagatgata
     5041 aaggaaaaga gattactttt gataaacaag aagtactggg ggatattact attacaggaa
     5101 ctgtcaccgg taatgtgtcg aaggtatata ctgcagtaat aaccccgacc ctggggggaa
     5161 gtgtaaagac aggaaagttt tctgctgcaa tactcgttac tgttacctat aactaatcgg
     5221 gggtgacaga taataaaaat aaaagagctg actgagttat cggggaacta atcccgaata
     5281 aacccacatt aataataaat actatttaag agctgttctt cacctccgga aaattattta
     5341 cccagttatg gagaggtttt atgtgccctg ataatacaca cgcaaaaaag cagtacctta
     5401 tcccaggtaa cgatattcat tatcccggac agaccaacca tgatgcctgt tttattccgg
     5461 taagtgtccg ccagtatgcc ggcgagcccc tgtatatcat cgtggcacac tggtgcctgt
     5521 tgcagcagaa ctgggttcag cgtaaccaga tagcagaggc gtttcacatc acggccagac
     5581 gggccagcta cctgattgcc tatctgcgaa gcaaaacatc gcgggtggtc agcatctgcc
     5641 gtcaccagac cctgcccaat aaagcacgac gctatgagat ttatgttatc cgggttcttg
     5701 acagtcccac cccgtccacg cgccgtgaaa aagccggacc gccgccggta tcaaaacgcc
     5761 gggtcggtaa tggtgacagg tcgatggcaa atgaactgtg gaaccggctg tgcagtaaca
     5821 gaaatgcggg aaagatcctg aaaaagaggg aggatgagga tgacagaaca taaccggata
     5881 ccggcccggc agattatcgt ttacggtgac tgctggccgg tgacgatcgc cgtggcacac
     5941 ctggtccgga gatttctgcc gggctgcaac tgtgaaaccg catacaggct gcctgttctg
     6001 ttgcagcaat tacgtcggaa accggaggcc atactgatac tgtgtctgcg tccccgtgaa
     6061 catctctttt tgttctattc cctgaggcag atactgccgg actacccggt tatgattatc
     6121 agcgatgagc tgtttttcag cgaccgggtg gtactgaagg tatacggcgg catcccggcg
     6181 ctgctggagc aggaactggc ggagatactt attcggtggc ggcgggatga acagtgggcc
     6241 gggggcgcac gcctgcgcag gacaggaggg ctggacgcct ttttgttatc tccggatccg
     6301 gtgacgggct ttctggaagt gccaccgata tttaacaatc cgaagcggtt gatgaactat
     6361 atggaccagt tgatgcaccg ggagatactg gcatgcggag tgagcctggc ccagttacgc
     6421 ttgcttcagg aagtttaccg tggacgggga aggttatcag cgctgtgtgg aaggctgaac
     6481 acgcaggaga agcaaatctg gcaggacaaa taccggttac tggtgaagct gggaatgcgg
     6541 aaccgattac gggaactgct gtttggtacc cggttttgta aatcactgca gcgaactccg
     6601 tttatcgctc cgcaataacc cgcctccggc gaccctatcc agaaacactg acacaccggc
     6661 taaacccggt ggcggtgggg tatgttttgc ctgtggtgta gtggagtaaa atacagaatt
     6721 caggcgggac gctgaatgta tggcctttca taccgtttga taagtaaaaa cgcttctgga
     6781 atgaaacccg aagtgaatga tacggcctga gcagaagcgt tacatattta ctgcatgatc
     6841 ccggtatagc catgaattcc catatacacg ccgaccagac caatcagaat gctcgaaaaa
     6901 tagggcgccc gccgggcaag cgtcgaaaaa ccactccagc gctttgctgc ctgttgaacg
     6961 cttatcgccg cgccaacgcc taccgtcacc agcgttaatg ccaggccaag actaaagctc
     7021 agcaccatcg tggcacccag cgtaaacgct ttaagctgga tacaaatcag taaaacggtg
     7081 atcgcagccg gacaggggat aagccctccg gtcaggccga acagcaggat ctgtccatta
     7141 ttcactgttt gaccatcaaa acggcgttga atatcggcag catgggcgcg ttcatgggca
     7201 tcctgatacg cttttgacgt tgcgccttcc ggatgtatgt gaccatgatg gtcatggtca
     7261 tggtcatggt catggtcatg gtcatggtcg taatggtggt cgtgatggtg gtcgtgatgg
     7321 tggtttcccg ccagccactg ctgctcgcct cgtcatgtcc gccagaacat ccagcacgcg
     7381 gtgctcagaa taatgatcgc agaaattaac tgcagccatg gttccactga ttgtgcggtg
     7441 aatgcccggc taagatacat cccacccagc gcgattaacc agacgatcgc ggtatgagaa
     7501 agcgttgctg ccagaccgag catgacagcc tgtttaaccg tacctttaat ggcaatgata
     7561 aaagccgcca tcatggtttt ggagtgccct ggttcaagcc cgtgcaaaat acctaataaa
     7621 atggcgctgg gaatgaagaa ccagccgttt ccttgctgaa gaagtgtcga aaattcaccc
     7681 atgagaatga ttcttagttg ttttatgtgg gcgtcattct actccccccc agtatggaat
     7741 actacccccc agtagcatcg taatgctata atttgtattc gttaatgtta gtgaggtgtt
     7801 gtaatgtcac ataccatccg ggacaaacaa aagcttaaag ccagaaccag caagattcag
     7861 gggcaggtga tagcgctaaa aaaaatgctg gatgaaccgc atgaatgcgc ggccgtgtta
     7921 caacagatcg cggcgattcg cggcgcggta aatggcttaa tgcgcgaggt gattaaaggg
     7981 catctgaccg agcatatcgt tcatcagagt gatgaagcca gacgtgaaga agatctggac
     8041 gtaatattaa aggtgctgga ttcttatata aaatagccgg gagttatatc ccggctatct
     8101 tttactttag ccgaaaaaca tcaccgatac gcaaagtaaa ccgacgacca acgtaatgaa
     8161 attacctatt gaacggtagg gtttcaatgc cggtatcagg tacgttgaca acgtgggcat
     8221 aataaacaga atcatcgcaa tgagcgggcc gctaatggca taaatcatag agatggcatt
     8281 cgggttaata cagcaaataa taaacgtaat cccggaaacc agcatgatag acagcgcgcg
     8341 attgaacgcc cggctttttt tcacgccaac ctgctgtagg gtggttctta ctatttcggt
     8401 tgcgccctcg atgacgccga aataggtgcc gaggaaagat ttcgacatgg ccacgacggc
     8461 aacgataata ccggaaatag agagccaggc cggcgcattg ggcatcatcg agagcgcgga
     8521 aaggatggta acgccttcgt tgcgcgcgtc ttcaatgtat gacggcggaa tggagagcag
     8581 gcagctaaag acaaagaaca gcacactcag gcagataatc aggtaggcga ccttcatgat
     8641 ctttttgcat ttatccatgg cctgatcgcc aaaattttcc cgtctgtcga tggcaaacgt
     8701 cgaaataatg ggcgtatggc taaaagcaaa aaccatcacc ggaatagaaa tccatacctg
     8761 gtgcaacgtg tgactatcca aagacatctg cccggtcagt aacgagggtt gccagcttcc
     8821 ggttaagtag agcgaaagga acaagaagta agcgataagt ggaaagacta aaaagcccat
     8881 tacgcgaaga gtggcatgtc ttcccattaa gaaaatcata ttcaggataa gtactacgcc
     8941 gaagctaact gccatccgga tgcgaatatc tatctgaata tgcttcgcta attgctctgt
     9001 cagggaattg gtaatcgcca cagcataaat taataccacg acaaaaaacg caatgaaata
     9061 aagcgtggta ataatactgc cgattttctt gccgtaataa tgagtaacgg cgccagtaat
     9121 tccctcacct gcagaagtct ttgaggaaag aataaactga cacagcgcct tatgcggcca
     9181 gtatgttaga ggccaggcga ccagcgcggt aataaatagc acgattgcgc ctgccgatcc
     9241 caactggatg ggaaggaaaa gagtgcctgc gcctacagcc gttccgtata atgcaaaact
     9301 ccagagagtc tcatcttttg accaaatttt agacattatt tgaatttatc aactataaaa
     9361 cacacaaaaa gaagcgcaat ttaccataaa tagcgtcagt tgggggcgtt ttaagcagat
     9421 ggatgtcgtg gaggaggagg gccgggagcg ttgcgatccc ggcaaaaaag agcaatatca
     9481 tgcactaacg cgctgttggc ggcgggtcac tattcgttgg cgtaaaacat cgtatgccca
     9541 gttgtacagc atcgtgtacg gcaaaaagaa caggaagaaa ccaatttcca gggtgaatgc
     9601 ttgtagcagg ctgacattca gtacccaggc gacaatactc acgccaatga caataaaccc
     9661 actttcaaat cctaacgcat ggagtgcgcg cactttggcg gttcgtctca cctgatgcgc
     9721 aggccacagt cgatcaaaca gagcgttata aatgatattc cagatcatgg ccgtcgttgc
     9781 cagcaatatc gtcaggccgc ccatctccag caccgagcgc tgcattagcc aggcggtcgt
     9841 tggcgccagt atcgcagtcg caataccttc aaaacagaca gcatggaaaa tacgctccgg
     9901 cagcgagcga cgttgtatgg cgtcatgttg cataaatgaa aaaaccttac tcttaa
//
LOCUS       DAJVKX010000149         9922 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.149, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000149 DAJVKX010000000
VERSION     DAJVKX010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9922
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.149"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            83..403
                     /locus_tag="OPY25_003871"
     CDS             83..403
                     /locus_tag="OPY25_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929365.1"
                     /translation="MTSFISSIAYASSSLNKQLSLLSENLLKEKIISFNIFCSISTYS
                     RINVRRWRKNLMSRNTYTLKMLPQTEQNEKEERLPFTFPPKILVLSLVKGIRIAFYLI
                     KKVC"
     gene            complement(413..754)
                     /gene="sigE"
                     /locus_tag="OPY25_003872"
     CDS             complement(413..754)
                     /gene="sigE"
                     /locus_tag="OPY25_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system chaperone SigE"
                     /protein_id="HCS0929366.1"
                     /translation="MESLLNRLYDALGLDAPEDEPLLIIDDGIQVYFNESDHTLEMCC
                     PFMPLPDDTLTLQHFLRLNYASAVTIGADADNTALVALYRLPQTSTEEEALTGFELFI
                     SNVKQLKEHYA"
     gene            complement(771..2456)
                     /gene="sopB"
                     /locus_tag="OPY25_003873"
     CDS             complement(771..2456)
                     /gene="sopB"
                     /locus_tag="OPY25_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector
                     inositol phosphate phosphatase SopB"
                     /protein_id="HCS0929367.1"
                     /translation="MQIQSFYHSASLKTQEAFKSLQKTLYNGMQILSGQGKAPAKAPD
                     ARPEIIVLREPGATWGNYLQHQKTSNHSLHNLYNLQRDLLTVAATVLGKQDPVLTSMA
                     NQMELAKVKADRPATKQEEAAAKALKKNLIELIAARTQQQNGLPAKEAHRFAAVAFRD
                     AQVKQLNNQPWQTIKNTLTHNGHHYTNTQLPAAEMKIGAKDIFPSAYEGKGVCSWDTK
                     NIHHANNLWMSTVSVHEDGKDKTLFCGIRHGVLSPYHEKDPLLRQAGAENKAKEVLAA
                     ALFSKPELLNRALEGEAVSLKLVSVGLLTASNIFGKEGTMVEDQMRAWQSLTQPGKMI
                     HLKIRNKDGDLQTVKIKPDVAAFNVGVNELALKLGFGLKASDSYNAEALHQLLGNDLR
                     PEARPGGWVGEWLAQYPDNYEVVNTLARQIKDIWKNNQHHKDGGEPYKLAQRLAMLAH
                     EIDAVPAWNCKSGKDRTGMMDSEIKRELISFHQTHMLSAPGSLPDSGGQKIFQKVLLN
                     SGNLEIQKQNTGGAGNKVMKNLSPEVLNLSYQKRVGDENIWQSVKGISSLITS"
     gene            2788..2958
                     /locus_tag="OPY25_003874"
     CDS             2788..2958
                     /locus_tag="OPY25_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HCS0929368.1"
                     /translation="MPAKPRTSKTVTKNIRFSYSMLEQIEFALKSEKTRNFSAWVKEA
                     CREKLCNTGHKL"
     gene            complement(2959..3069)
                     /locus_tag="OPY25_003875"
     CDS             complement(2959..3069)
                     /locus_tag="OPY25_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929369.1"
                     /translation="MTLQTNISRETKAAKTQEVYKHVVLFKMAAPSYIRR"
     gene            complement(3178..4647)
                     /locus_tag="OPY25_003876"
     CDS             complement(3178..4647)
                     /locus_tag="OPY25_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HCS0929370.1"
                     /translation="MKKYLAFAVTLLGMGKVIACTTLLVGNQASADGSFIIARNEDGS
                     ANNAKHKVIHPVAFHQQGEYKAHRNNFSWPLPETAMRYTAIHDFDTNDNAMGEAGFNS
                     AGVGMSATETIYNGRAALAADPYVTKTGITEDAIESVILPVAQSARQGAKLLGDIIEQ
                     KGAGEGFGVAFIDSKEIWYLETGSGHQWLAVRLPADSYFVSANQGRLRHYDPNDNANY
                     MASPTLVSFAKKQGLYDPARGEFDFHQAYSQDNKNDTTYNYPRVWTLQHQFNPHLDTV
                     VSEGETFSVFLTPITKISVAAVKNALRNHYQGTSHDPYASHNPQEPWRPISVFRTQES
                     HILQVRPKLPQAIGNVEYIAYGMPSLSVYLPYYQGMRHYQPGDDKGTDRASNDSTYWT
                     FRTLQTLVMQDYNTFAPDVQHAWKTFEQQTAKQQYKMEQSYLRLYASHPKEAQRLLQN
                     FEDKTMQNAQTLARRLTNNIITTMTYRTDMKYHFSSTQP"
     gene            complement(4820..6184)
                     /locus_tag="OPY25_003877"
     CDS             complement(4820..6184)
                     /locus_tag="OPY25_003877"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal sensor histidine kinase"
                     /protein_id="HCS0929371.1"
                     /translation="MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMT
                     LINRAAQMQQLLLDGARPENLPLYFNRMVDTKQDILLIHSATGHNVAINHSGIPDQRF
                     NEIPLAKNITRETLFRQAVQGTELTAVRVNARSGDNPLTLTIARLATERRQMLAQYRR
                     NSLLISLIAILVCSALSPLVIRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRP
                     LGQALNTMRQKLSDDFERLNQFADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQAL
                     VDNIEELEGLSRLTENILFLARAEHQNIAVKKQPVSLNALVENMLDYLSPLAEEKHIC
                     FINQCQGTVWADEILLQRVLSNLLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSP
                     TADADKLFRRFWRGDNARHTAGFGLGLSLVNAIALLHGGSASYRYADEHNIFSVRLPD
                     SGDS"
     gene            complement(6177..6857)
                     /gene="hprR"
                     /locus_tag="OPY25_003878"
     CDS             complement(6177..6857)
                     /gene="hprR"
                     /locus_tag="OPY25_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HCS0929372.1"
                     /translation="MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEH
                     YSLIILDIMLPGLDGWQVLRALRTAYQPPVICLTARDSVEDRVKGLEAGANDYLVKPF
                     SFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLA
                     SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRL
                     QAETSQNG"
     gene            6993..7403
                     /gene="hiuH"
                     /locus_tag="OPY25_003879"
     CDS             6993..7403
                     /gene="hiuH"
                     /locus_tag="OPY25_003879"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HCS0929373.1"
                     /translation="MKRYILATAIASLVAAPAMALAAGSNILSVHILDQQTGKPAPGV
                     EVVLEQKKDNGWTQLNTGHTDQDGRIKALWPEKAAAPGDYRVIFKTGQYFESKKLDTF
                     FPEIPVEFHISKTNEHYHVPLLLSQYGYSTYRGS"
     gene            complement(7736..8248)
                     /locus_tag="OPY25_003880"
     CDS             complement(7736..8248)
                     /locus_tag="OPY25_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase reductase
                     subunit"
                     /protein_id="HCS0929374.1"
                     /translation="MQVDEQRLRFRDAMASLAAAVNIVTTAGHAGRCGITATAVCSVT
                     DTPPSVMVCINANSAMNPVFQGNGRLCINVLNHEQELMARHFAGMTGMAMEERFHQPC
                     WQNGPLGQPVLNGALASLEGEISEVQTIGTHLVYLVAIKNIILSQEGHGLIYFKRRFH
                     PVRLEMEAPV"
     gene            complement(8266..9828)
                     /gene="hpaB"
                     /locus_tag="OPY25_003881"
     CDS             complement(8266..9828)
                     /gene="hpaB"
                     /locus_tag="OPY25_003881"
                     /EC_number="1.14.14.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase,
                     oxygenase component"
                     /protein_id="HCS0929375.1"
                     /translation="MKPEDFRTDNKRPLTGEEYLKSLQDGREIYIYGERVKDVTTHPA
                     FRNAAASVAQLYDALHKPSMQDTLCWNTDTGSGGYTHKFFRVAKSADDLRQQRDAIAE
                     WSRLSYGWMGRTPDYKAAFGCALGANPAFYGQFEQNARNWYTRIQETGLYFNHAIVNP
                     PIDRHKPADEVKDVYIKLEKETDAGIIVSGAKVVATNSALTHYNMIGFGSAQVMGENP
                     DFALMFVAPMDAEGVKLISRASYEMVAGATGSPFDYPLSSRFDENDAILVMDKVLIPW
                     ENVLIYRDFDRCRRWTMEGGFARMYPLQACVRLAVKLDFITALLKKSLECTGTVEFRG
                     VQADLGEVVAWRNMFWALSDSMCSEATPWVNGAWLPDHAALQTYRVMAPMAYAKIKNI
                     IERNVTSGLIYLPSSARDLNNPQIDQYLAKYVRGSNGMDHVERIKILKLMWDAIGSEF
                     GGRHELYEINYSGSQDEIRLQCLRQAQSSGNMDKMMAMVDRCLSEYDQNGWTVSHLHN
                     NDDINQLDKLLK"
BASE COUNT         2418 a         2415 c         2386 g         2703 t
ORIGIN      
        1 catctgacaa gaggcgatga tatctgccat aacggtgaag cagaagtaat atcacccgtg
       61 aataataaga ttatccttgc tattgacttc cttcatttcc agcatagctt acgcctcatc
      121 atcattgaat aaacaattaa gtttgttgag cgaaaattta cttaaagaaa aaataataag
      181 ctttaatatt ttttgcagca tttcaactta tagcagaata aatgtgcgta gatggcgtaa
      241 aaacctgatg agcaggaata cttacacact aaaaatgctc ccgcaaacag agcaaaatga
      301 gaaagaggaa cgtttgccct ttacatttcc accaaagatt ctggttttgt ctcttgtaaa
      361 gggcatacgt atcgcgtttt atctcattaa gaaagtatgt tgacgtatta aattatgcat
      421 aatgctcttt caattgcttc acgtttgaaa tgaataattc aaaaccagtg agcgcctctt
      481 cttcggtact ggtttgcggc aagcgataaa gcgccactaa agcagtattg tctgcatcag
      541 cgccgatagt gacggcgctg gcgtagttaa gacgtaaaaa atgctgcaaa gtcagagtgt
      601 cgtcaggcag tggcataaag ggacagcaca tttccagtgt atgatcggat tcattaaaat
      661 aaacctgtat cccatcatca atgataagca gtggctcatc ttctggcgca tccaggccta
      721 acgcgtcata taaacgattt aatagacttt ccatatagtt acctcaagac tcaagatgtg
      781 attaatgaag aaataccttt tactgactgc caaatatttt catccccaac tcgtttttga
      841 taggaaagat tgagcacctc tggcgataaa tttttcatta ctttgtttcc cgccccgccc
      901 gtattttgtt tctgaatctc caggttaccg ctattcagta atactttttg gaaaattttc
      961 tgtccaccgc tatccggaag actaccaggc gcacttaaca tatgggtctg atggaaagaa
     1021 atgagctctc gcttgatttc tgaatccatc atccctgtac gatctttgcc gcttttacaa
     1081 ttccaggcgg gcaccgcgtc aatttcatgg gctaacatgg caaggcgttg tgcgagttta
     1141 tagggttcgc cgccatcttt atgatgttgg ttatttttcc agatatcctt aatctggcgc
     1201 gctaatgtat tgacgacctc ataattatcc gggtattgcg ccagccattc gccaacccag
     1261 ccacctggtc tggcttcagg gcgtaaatca ttgcctaata actgatgtag cgcttcggca
     1321 ttatagctat ctgatgcttt aaggccaaag ccgagcttga gcgccagctc attaacaccc
     1381 acattaaatg cggcgacgtc cggttttatt tttaccgtct gtagatcgcc atctttattg
     1441 cggattttta aatgaatcat ttttcccggc tgggtcaacg attgccatgc gcgcatttga
     1501 tcctcgacca tagttccctc tttgccgaaa atattcgacg cggtgagtaa cccgacggat
     1561 accagtttca ggcttaccgc ttcgccctct aaggctctgt taagcaactc aggtttacta
     1621 aaaagtgccg cagctaatac ttctttggct ttgttttcag cgccggcctg acgcagaagc
     1681 ggatcttttt catgataggg ggaaagcaca ccatgacgta tcccgcaaaa aagcgtttta
     1741 tctttaccgt cctcatgcac actcaccgtg gacatccaca aattattggc gtgatgaata
     1801 ttcttggtat cccaactgca tacgcccttt ccctcataag cactgggaaa gatatctttt
     1861 gcgccgattt tcatctctgc ggcagggagc tgcgtgttgg tatagtgatg cccgttatgc
     1921 gtgagtgtat tttttatggt ttgccagggc tggttattga gctgcttgac ctgagcatct
     1981 ctaaacgcta ctgccgcaaa gcgatgagct tcttttgcag gtaagccatt ttgctgctga
     2041 gtgcgtgctg caataagttc gataagattt ttcttcaatg cttttgccgc agcttcttct
     2101 tgttttgttg ctggccggtc cgctttaact ttggctaact ccatttggtt tgccattgac
     2161 gttagaaccg ggtcttgttt acccagaacg gttgccgcga cggtaagaag atcgcgctgt
     2221 aagttataga ggttatgcag cgagtggtta gacgtcttct gatgctgtag ataattcccc
     2281 catgtcgcgc caggttctcg caggacaata atttccgggc gagcgtcggg cgctttagcc
     2341 ggcgctttgc cctggcctga gagaatctgc attccgttgt ataaggtttt ttgtaggctt
     2401 ttaaaagcct cctgggtttt tagtgaagct gagtgataga agctctgtat ttgcatagcg
     2461 tttttaatat tcctgaatag gggagtggga acattcaaca gggttaacaa tcttttaaaa
     2521 ggatgtgact tttatgcacc aggaacttta aaaaaatgtc ctttttaatg aggaaacgct
     2581 tctgatcagg cggggaggca tcctgacgtc catacgtagt ggcgatcatg ggggagatcg
     2641 gtacatcaaa tgttcataaa atctacaaac ttcacaattt agggcacaac ttttattgaa
     2701 aacccacctt cttgattcag atcaaattca ccgatttact cctgcgtaaa gtaacggcgt
     2761 tacatcaaat gttatacagg tgtgtgtatg ccagcaaagc cccggacgag taagaccgtg
     2821 acgaagaata ttcgtttttc ctattccatg cttgaacaga tagaattcgc gttgaaatct
     2881 gaaaagacgc ggaatttttc agcatgggta aaagaggcct gtcgggaaaa gttatgtaac
     2941 acgggacata agctgtagtt atcgtcttat gtaagagggg gcggccattt tgaaaagaac
     3001 aacgtgctta tatacctcct gggtctttgc cgcttttgtc tctctgctga tatttgtctg
     3061 gagtgtcata aactatcctc tctatgaatc cataataatt attgtctttt atatctggct
     3121 aattctggta ccgctttatc ttattgtgta tgagtggcta atagattgtc attaaattta
     3181 tggctgcgta cttgaaaagt gatatttcat atctgtgcgg taagtcattg tcgtaataat
     3241 attattggtc aggcgacggg cgagcgtctg cgcattttgc atcgttttat cttcaaaatt
     3301 ttgcagtaag cgttgtgctt ctttcggatg cgacgcatat aatctcagat agctctgctc
     3361 catcttatac tgttgcttag ctgtttgctg ttcaaatgtt ttccaggcat gttgcacatc
     3421 tggcgcaaac gtattgtagt cttgcataac cagtgtttgc agcgtgcgga atgtccagta
     3481 ggtagagtcg ttgctcgccc gatcggttcc tttatcatct ccgggttgat aatgacgcat
     3541 cccctggtaa taggggagat agacgctaag agatggcatt ccataggcga tgtattctac
     3601 gttgccgata gcctgcggta atttcggtct gacctgtaaa atatgtgact cctgggtacg
     3661 aaaaacggat ataggtcgcc atggttcttg tggattatga ctggcataag ggtcgtgcga
     3721 cgttccctga tagtgattgc gtaacgcgtt ttttactgcc gccacgctga tcttcgttat
     3781 tggcgttaaa aaaacagaaa atgtttcccc ttcgctaacg accgtatcca gatgcggatt
     3841 aaactggtgt tgtagcgtcc agacgcgcgg ataattatag gtggtatcgt ttttgttatc
     3901 ctgcgaatag gcttgatgaa agtcgaattc gccgcgggcc ggatcatata atccctgctt
     3961 tttcgcaaag cttactaacg ttggtgacgc catataattc gcgttatcat tcggatcgta
     4021 atggcgtaaa cgtccctgat tggcggaaac gaaatagcta tctgccggaa gtcgtactgc
     4081 cagccattga tgtccgcttc ccgtctccag ataccatatc tctttgctat caataaacgc
     4141 gacgccgaaa ccttcgcccg cgcctttttg ttcaataata tctcccagta atttggcgcc
     4201 ctgacgcgcc gattgcgcca ctggcaggat cacggactca atggcgtctt ccgtgattcc
     4261 cgtttttgtc acgtaaggat cggcagccag cgccgctctg ccgttgtaaa tggtttccgt
     4321 tgcgctcatt ccgacgcccg ccgaattgaa accggcttca cccatggcgt tatcgttagt
     4381 atcaaagtca tgaatcgccg tatagcgcat cgctgtctcc ggaagcggcc agctaaaatt
     4441 gttgcgatgt gctttatact cgccttgttg atgaaacgcg acgggatgaa taaccttatg
     4501 cttggcgtta tttgccgagc catcctcgtt gcgcgcgata ataaaggagc cgtcagccga
     4561 agcctgattg cctaccaaaa gggtagtaca ggcgatgact ttacccatac ccagcagcgt
     4621 aacggcgaaa gcaagatact ttttcataaa ggttcccact gaataacgcg ttatgggatg
     4681 aattgaccct ggattggaaa ccgagaaagt gatcgagcca gcaatattct ttaccggcat
     4741 cctttatttt ctttttattg aggttgtatt gataaccaca gccctgtggc agggaagggg
     4801 aacagaacct gtactgacct tagctatcac cgctatcagg cagacgaacc gaaaagatat
     4861 tatgttcatc ggcatagcgg taagatgccg agccaccgtg caatagggca atcgcgttaa
     4921 ctaacgataa ccccaggccg aaaccggcag tgtggcgggc attatctcct cgccaaaaac
     4981 gccggaaaag cttatccgca tcggcggtgg ggctgcccgg attagcgacc cgaatttctg
     5041 caacgttatc atcataagcg ctttcaatac gtatcacggc gttttcatca gaataacgga
     5101 tggcattcgt cagcaggttt gagagcactc tttgtaataa tatttcgtca gcccataccg
     5161 ttccctgaca ttgatttata aaacagatgt gcttctcttc ggcaaggggg ctaagataat
     5221 ccagcatatt ttcgaccagc gcattgagcg aaacaggctg tttttttacc gctatattct
     5281 ggtgctccgc gcgtgccaga aagagaatat tttctgtcag tcgcgacagt ccctccagct
     5341 cttcaatatt atcgacaagg gcttgttgat actcttcggc gctgcgttcc tgactcagca
     5401 taacctgatt cttccccagt aaaatattaa ccggcgtgcg cagctcatgc gccagatcgt
     5461 cggcaaattg gttcaggcgt tcaaaatcgt cggaaagctt ctggcgcatg gtatttagcg
     5521 cttgcccaag cggcctgagc tcgacgggta acgcctgttc cgccagcggc tggcgaagtg
     5581 tgccgctatc tgtcgccgcg gtgagtcggc tgagcgacgt aatggcccgc agcccgtttc
     5641 tgatgactaa tggactgagc gccgaacaga cgaggatcgc gataaggcta atcagcaaac
     5701 tgttgcggcg atattgcgcc agcatttgcc gcctttccgt cgccagcctg gcaatagtaa
     5761 gggtcagcgg gttatcgccg cttctggcgt ttactcgtac cgcggtcagc tccgtgcctt
     5821 gtaccgcctg gcgaaataag gtttcgcggg tgatgttttt agccagcgga atctcgttaa
     5881 agcgttggtc ggggatgccg ctatgattaa tcgcaacatt atggcctgtt gctgagtgga
     5941 tcaataagat atcctgcttc gtatccacca tccgattgaa atagagcggc agattttccg
     6001 gcctggcgcc atccagtaac agttgctgca tttgcgccgc ccgatttatt agcgtcatat
     6061 catcccgata cgttaattct ttgctcagcg cgttatagag cgtccagcta atgccggtac
     6121 aggcgaggat aagtatggcg ataaaagaaa ttgtcaggcg cagcgtcatt gataacttaa
     6181 ccattctgcg acgtttccgc ctgtaatcga taacccatcc cctggacggt cataatgagc
     6241 ttcttttcaa atggatcgtc tactttggcg cgcagccgac gaatcgcgac atcaacggtg
     6301 ttggtttcac tatcaaagtt aattccccaa acttcgctgg cgatcgcggt tcggggcacg
     6361 atttcccctg cccgggacgc cagtaaccag aggagcagga attctttgcg ggtcagggaa
     6421 atcggtttgc catttcgtaa caccgattgc tttgtggcat ccatgtccag accattgatc
     6481 gtcagtcggg taaagaccgg gacatgctgt ctgagttgag ctctcacccg ggccagcagt
     6541 tcggcgaagg aaaaaggctt aacaaggtaa tcattagcgc ccgcctcaag acctttgacg
     6601 cgatcctcaa ccgagtcgcg cgccgtcagg caaataacag ggggctgata tgcagtgcgc
     6661 aacgcgcgta aaacctgcca tccatcaagc cccggcagca taatatcaag aataatcaat
     6721 gaataatgtt cctgaagggc taggtgtaat ccgtctcgtc catcacaggc ataatcaacc
     6781 acatagcctg cctccgtgag tccctgacgt acccactcaa tggttttctg gttatcttca
     6841 atcaataaaa tcttcatcaa cgcagtatgc cataggcttg ttagcgaatc cgtaaatctc
     6901 caacaagatg acataattgt catgtccgtg taaggttaat cctggacgcg ccagatatat
     6961 tttcctgcat caataccgta aaggagtgaa gcatgaaacg atatatactg gctaccgcga
     7021 tagcgtctct tgttgcagcc ccggcaatgg cgctggccgc tggcagcaat attctcagcg
     7081 tacatattct cgatcagcaa acaggcaaac cagcgcccgg cgtggaggtg gtactggagc
     7141 agaaaaagga taacggatgg acgcaattaa acaccgggca taccgaccag gatggacgaa
     7201 ttaaagcact gtggcccgaa aaagctgccg cgccggggga ttatcgcgtt atttttaaaa
     7261 ccggccagta ttttgaaagt aaaaaactgg acacgttttt cccggagatt cccgtcgagt
     7321 ttcatatcag caaaacgaat gagcactatc atgtgccgct gttattaagt cagtatggtt
     7381 attcaaccta tcgcgggagc taatttagag cctatcctat tagggctatt ttacttgcca
     7441 ttttggtcct gggcagtgct cgccaaaacg cgttagcgtt ttgaacgccg cttgcggcgg
     7501 cccgaagggc gagcgtagcg agtcaaacct cacgtacaac gtgtacgctc cggtttttgc
     7561 gcgctgtccg tgtccaaaca ggctgcgcca ataacgcctg gtgggacagg ctcttagatt
     7621 ttattaatcg ccgggattta tggcgagcaa acatcgcggc gggaataaaa atcttcagcg
     7681 tatcgactct cctcccacaa gcggtggtta tcccgcttgt gggtatgagt gacggttaaa
     7741 caggcgcttc catctcaagt ctgaccggat gaaaacggcg tttgaaataa atcaggccat
     7801 gcccctcctg gctaagaata atatttttga tcgccaccag atacaccaga tgcgtgccaa
     7861 tggtttgtac ctcgctgatc tcgccttcaa gactggccag cgcgccgtta agtaccggct
     7921 ggcccagcgg cccgttttgc caacatggct ggtgaaaacg ctcctccatc gccatccccg
     7981 tcataccggc aaagtggcgc gccatcagct cctgctcatg gttaagtaca ttaatgcaca
     8041 gcctgccgtt gccctgaaaa acggggttca tggcgctatt ggcattaata cataccatca
     8101 cggagggcgg cgtatcagtg actgagcaaa ccgctgttgc ggtgataccg cagcgtccgg
     8161 cgtgacccgc cgtggttacg atgttgaccg ctgccgccag acttgccatc gcatcgcgaa
     8221 aacgcagacg ttgttcatct acttgcatga gaacctcctg ccgcgttatt tcagcagctt
     8281 atccagttga ttgatgtcgt cgttattgtg caaatgcgaa accgtccagc cattctgatc
     8341 gtattcggag aggcagcgat cgaccattgc catcatctta tccatattgc cggagctctg
     8401 ggcctgacgc agacactgca gacgaatttc atcctggctg cccgagtagt taatctcgta
     8461 cagctcatgg cgaccgccaa actcgctgcc gatggcatcc cacatcaatt taagaatttt
     8521 gatacgttca acatggtcca ttccgttaga gccgcgtacg tatttcgcca ggtactggtc
     8581 gatttgcgga ttattcagat cgcgggcgct ggaaggcagg taaatcaggc cgctggtaac
     8641 gttacgttca ataatatttt taattttcgc gtaggccatt ggggccatca cacgataggt
     8701 ttgcagcgcg gcgtggtccg gtagccaggc gccgtttacc cacggggttg cttcagaaca
     8761 catagaatcg ctcaatgccc agaacatatt gcgccaggcc acgacttcgc cgagatcggc
     8821 ctgcacgccc cggaactcta cggtacccgt acattcgagc gattttttca gcagcgcggt
     8881 aatgaaatca agttttaccg ccagacgaac acaggcttgc agtggataca tacgggcaaa
     8941 gccgccttcc atcgtccagc gacgacaacg atcgaaatca cggtaaatta atacgttttc
     9001 ccacgggatc agcaccttgt ccatcaccag aatggcatcg ttttcatcaa aacggctgga
     9061 gaggggataa tcaaacggcg agcccgtcgc gcccgcgacc atttcatacg aggcgcgcga
     9121 aataagtttt acgccttcgg catccattgg cgcgacaaac atcagagcaa aatccgggtt
     9181 ttcgcccatc acctgggctg agccgaaacc aatcatgttg tagtgagtca gggcggagtt
     9241 agtggcgaca actttcgccc cgctgacaat aatcccggcg tccgtctctt tctccagctt
     9301 gatatagacg tctttcactt cgtcggcagg tttgtggcgg tcaatgggcg ggttgacgat
     9361 tgcatggtta aagtacaggc cggtctcctg aatacgggtg taccagttac gggcgttctg
     9421 ctcaaactgg ccgtagaagg ctgggttagc gcccagagcg cagccaaagg cggctttgta
     9481 atccggtgtg cgtcccatcc agccgtaact caggcgtgac cactcggcga tagcatcacg
     9541 ctgttggcgc agatcgtctg cgcttttcgc cacgcggaaa aatttatgcg tataaccgcc
     9601 gctgccggta tcggtattcc agcacagggt atcttgcatc gacggtttat gtaatgcgtc
     9661 atacagttgt gcgacagagg ctgcggcatt gcggaatgcc ggatgtgtcg taacatcttt
     9721 aacgcgttcg ccgtaaatat aaatttcccg cccgtcctgc aggcttttta aatactcttc
     9781 gcccgttaac ggacgcttgt tatcagtacg aaaatcttca ggtttcattg cggcctcttc
     9841 ctcgttaatc ggaatttttt tgttaataat atgtttctta tttgttgttt aattgaatgg
     9901 gcagaagcgt aaactgtgaa ga
//
LOCUS       DAJVKX010000150         9899 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.150, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000150 DAJVKX010000000
VERSION     DAJVKX010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9899
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.150"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            154..1209
                     /locus_tag="OPY25_003882"
     CDS             154..1209
                     /locus_tag="OPY25_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CZB domain-containing protein"
                     /protein_id="HCS0929376.1"
                     /translation="MFKKVLGLRHWNNNVVKIPPPAESGANASDVVVDTPEPYERILC
                     QKILMGISTIDIIRNAIIKSCEQLNIEKERINELNEQNDKARSSLKSLVEFITEIGTT
                     SSDIGCRMGDLNTSLTQINACIKEIQKIANQTNLIAINSAIEAARVGDAGRGFSVISK
                     EVKNLSEDVKHSSKSVSTLTSVIKDNTARVSEVLDNQQPVIDNITTNINQIVESIGIV
                     IDKSLSMKSVMQYISTVQFLNIVKVDHVIWKMEVYKLLLNKDINSKITMHDQCRLGKW
                     YYGFEGQQFSNYYSFRSLEAPHKEVHTAGHSALNYFAAGDMNAMSQELDRMERSSNEV
                     VNQLEMLAVDLLKETTV"
     gene            complement(1509..2921)
                     /gene="uxaC"
                     /locus_tag="OPY25_003883"
     CDS             complement(1509..2921)
                     /gene="uxaC"
                     /locus_tag="OPY25_003883"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCS0929377.1"
                     /translation="MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADD
                     RRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLY
                     HWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDD
                     PIDSLEYHHQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDD
                     LRQALTRRLDHFAACGCRASDHGIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQ
                     FTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSR
                     LLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGM
                     LRQLEQLSQMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAM
                     LSRMVQDICFNNAQRYFTIK"
     gene            complement(2933..4405)
                     /locus_tag="OPY25_003884"
     CDS             complement(2933..4405)
                     /locus_tag="OPY25_003884"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HCS0929378.1"
                     /translation="MEQNIATAQVSVARPNWDKSRLVSRIVHLGCGAFHRAHQALFTH
                     HLLEKSDSDWGICEVNLMPGNDARLIANLKAQNLLYTVAERGAESTELKIIGSMKEAL
                     HPEFDGHAGILAAMARPETAIVSLTVTEKGYCTDPASGELDVNNPLIQNDLAHPQQPK
                     SAIGYIVEALNMRREQGLKAFTVLSCDNVRENGHVAKAAVLGLAKARDAALAAWIADN
                     VTFPCTMVDRIVPAATEETLQLVADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDT
                     VGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYDTIADTMTNPAYRRAALALMLD
                     EQAPTLSMPEGTDLEGYANLLIARFTNPSLKHRTWQIAMDGSQKLPQRLLDPVRLHLQ
                     QGDDYRRLTLGVAGWMRYVGGVDEQGKTIDVVDPLLAQYQAIHQQYQTPEERVRGLLA
                     IESIFGNDLPKNHEFVQAVTDAYQQLLQNGAKATVEALAK"
     gene            complement(4516..5700)
                     /gene="uxuA"
                     /locus_tag="OPY25_003885"
     CDS             complement(4516..5700)
                     /gene="uxuA"
                     /locus_tag="OPY25_003885"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCS0929379.1"
                     /translation="MKQTWRWYGPNDPVTLSDVRQAGATGVVTALHHIPNGEIWSVDE
                     IQKRKAIVEEAGLEWSVVESVPIHEDIKTHTGQYDLWIKNYQQTLRNLAQCGIYTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQAER
                     RFATMSEEDKARLTRNIIAGLPGAEEGYTLDQFRQHLATYKDIDKAKLREHFAYFLKA
                     IIPVADEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTLREENPKTFHEAAHLHGDVDMYEVVKAIVEEE
                     HRRKAEGSDDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SK"
     gene            6105..7409
                     /locus_tag="OPY25_003886"
     CDS             6105..7409
                     /locus_tag="OPY25_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929380.1"
                     /translation="MKMTKLRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQ
                     QYSWVVSAFQLCYTIAQPITGYLMDVIGLKIGFFIFALLWSLINMAHALAGGWISLAF
                     LRGLMGLTEASAIPAGIKASAEWFPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTF
                     ADSGIGTEMAFVITGGIGVLFAITWFLIYNSPNKHPWITHKELRYIEDGQESYLQDDN
                     KKPAVKEIVKKRNFWALAITRFLADPAWGTLSFWMPLYLINVMHLPLKEIAMFAWLPF
                     LAADFGCVAGGFLAKFFMEKMHMTTINARRCSFTIGAVLMISIGFVSITTNPYVAIAL
                     MSIGGFAHQTLSTVVITMSADLFKKNEVATVAGLAGSAAWMGQLSFNLFMGALVAIIG
                     YGPFFIALSLFDIIGAIILWVLIKDPEKHHPPMTEQPLASHR"
     gene            7885..8727
                     /locus_tag="OPY25_003887"
     CDS             7885..8727
                     /locus_tag="OPY25_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001787272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HCS0929381.1"
                     /translation="MVTEINTFEDFITKVRILLNKSQGADAVIFPELFTIELFTLLKK
                     WQERPISHLTLIDQFTDAYKQLFQQEAKERGQFIIAGSHLEQTGADRYENVAHIWGPD
                     GEHYAHSKTHIFPAERGWYTQEGDKMAVFQLPFAKVGFNICYEAEIPECAATLAEQGA
                     ELILTPSATFTEQGFWRVRHCCHARCIENQIYLVHCCLGGNPGGPLPGCWARSSILSP
                     CDVVWKNPQGIIAEAHVNQEDVISGEINLDVLYENRLGGAATTFKDRRRKAGIYNIWP
                     SHIK"
     gene            8766..9689
                     /locus_tag="OPY25_003888"
     CDS             8766..9689
                     /locus_tag="OPY25_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HCS0929382.1"
                     /translation="MGYLKLPEGKRIAVNLGVDVDAQSLWLGGFNRPSPSFMSRGEFG
                     AQVGVPRLLKLFKENNIKTTFFIPGHTVDTFPEISKAIFDAGHEIAHHGYYHENPTLV
                     NRDTERRLMDLAFACYKRHFGIRPVGYRSPYWDYSENTLDLLEEAGFLYDSSLMARDL
                     VPYHPQRWQVNWETGNIAGPASAILEIPVSWYLDDFPALAYTGNQEGMSDTDGVLRRW
                     KDIFTYAYNHQENGLYAMALHPQIIGHGHHMMMLSRLIEHIKGHDGVWFATCEEIASV
                     WVDDEEDRQKMLRPDVRGVAPVPDDYGWPGK"
BASE COUNT         2425 a         2340 c         2516 g         2618 t
ORIGIN      
        1 gtaattattt aagtttagtg gacattttgt cttattctgg tgaacgtatg gttatggcag
       61 atgacagccg atttttcatt atgttagcat gagttgataa tactttatcc aggcatagat
      121 caggatgtcc acatataata aggagaatgg tatatgttta aaaaagtatt aggcttgcgc
      181 cactggaata ataatgttgt aaaaataccg ccgccagcag aatctggcgc taatgcgtct
      241 gacgtggtgg tggatactcc tgagccttat gagcggatac tgtgtcaaaa aattctgatg
      301 gggatctcga cgatcgatat cattcgtaat gccatcatta agtcctgtga gcagctcaat
      361 attgaaaaag aacgcattaa tgaacttaac gaacagaatg ataaagccag aagttcatta
      421 aaatcgctcg tggaatttat caccgaaatt ggcacgactt catcagatat tggctgtcgt
      481 atgggcgact taaatacctc cttaacgcaa attaatgcgt gtattaaaga gatacagaag
      541 atcgctaacc agaccaattt gatagcgatt aactccgcga tcgaggccgc gcgcgtaggg
      601 gatgccgggc gtggttttag cgttatttcg aaagaagtga aaaacctgtc cgaagatgtt
      661 aaacacagtt cgaaaagcgt cagtacgtta acctctgtaa tcaaagataa tacggccaga
      721 gtgagtgagg tgctggataa ccaacagccg gttattgata atattacgac taacataaat
      781 caaattgtgg agtctattgg catcgtcatt gataaatcgc tgagcatgaa atcggtcatg
      841 cagtacatct ctacggtgca gtttttgaat attgtcaaag ttgaccatgt tatctggaaa
      901 atggaagtct acaaattact cttaaataaa gacataaaca gtaaaataac gatgcacgat
      961 cagtgtcggc tggggaaatg gtactacggt tttgaagggc agcagtttag caattactac
     1021 agtttccgta gtctggaagc gccgcataaa gaggtgcata ccgctggtca ctctgcgctg
     1081 aactattttg ccgcaggcga tatgaatgcg atgtcgcaag aactcgacag aatggagcga
     1141 tccagtaatg aggtggttaa ccagctggaa atgctggctg tcgatttgtt aaaagaaacc
     1201 acagtgtgaa gtcatgagtt attaccgtat aaccaacagg agccatcatc aacaggactg
     1261 atgtatcaca ctttctgcac tggagttatt ccggacagag aaaaaaagca tgacgcagaa
     1321 gatggctgtg tttgtttacc cgaatcactt accttagtaa gtgattcggg attaatcagc
     1381 aacctctttg ctttttatcg gtggccagac tttggctgga aaagtgcgtt actgctaaat
     1441 ttctcactct cttaccgcct tcctgcccct cgaaatacct gaaacctgtg ctcacagatt
     1501 aatagcgatt atttaatcgt gaaataacgc tgggcattat tgaagcagat atcctgaacc
     1561 atacggctta acatcgcttc atcatcagga atctctccgt cctgcgccca ctgtcccagc
     1621 aggttacaga gaatacgccg gaaatattca tgtcgcgtat aagaaaggaa actgcgggag
     1681 tcggtcagca tcccgacaaa ctgacttaac agtcccattt gcgacagttg ctccagttgg
     1741 cgcagcatcc cgtctttctg atcgttaaac caccagccgg aaccaaactg cacttttccg
     1801 gcaattcccg gcccctggaa gttaccgatc atggtcgcca ggacttcgtt atcacgtggg
     1861 ttcaggcaat agaggatagt cttgggcagt tcattggtca catccatact gtcgagcaaa
     1921 cgggagagcg cccagctaat gttattatcg ccaatagagt caaagccggt atccggcccg
     1981 agcaggcgga acatacgggt attattgtta cggatcgcgc caatatgtag ctgcatcacc
     2041 cagccgcgcg cggcgtactg acggcccagc cagaccagca ccgccgtggt aaactgggcg
     2101 atctcaagtt cgctcaacgt ttcgcctgcc agacgtttgc ccagaatggc gtcaagctgc
     2161 gcgtcgtcgg gcaccggcgc aaatcgcagc gtttcaatgc catgatcgga cgcgcggcag
     2221 ccgcaggcgg cgaaatggtc gaggcggcga gtgagcgcct gacgtaaatc gtcgaaacgg
     2281 gtaatgctga catctgccgc cgcttccagt ttccccaggt aatcgacaaa gccgtccagt
     2341 tcgattttga aaactttgtc ggggcgccag cttggcgcga cttcaatatc aatgctgtcg
     2401 tcggcggcta tctggtggtg atattccaga gaatctatag ggtcgtcggt ggttccgacc
     2461 atccgcacat tcatctgctg cataataccg cgcgcggaaa aggccggcgt cgccagtttc
     2521 tcattacact gcgtccagat actttccgcg gtatccggtc cgaacagcgt acctgtaatg
     2581 ccaaatggac ggcgtagttc aaggtgcgtc cagtgataca gcggattgcc cagcgttttt
     2641 ggaacggtat tggcccaggc catatatttt tcataatcgc tggtctcttt gccggtgatc
     2701 agcgactcat ccacgcctgc gcttcgtagc gctcgccatt tatagtggtc gccttccagc
     2761 cagatctgac cgaggttatc gaaacggcga tcgtcggcga tttcctgcgg acttaaatgg
     2821 cagtggaagt cataaatcgg catgggcgcg gcgtatttat ggtacagcgt gcgggcaatg
     2881 tcgtttttaa gtagaaaatc ttcagtcata aacgtagcca tgatttatct ccttacttag
     2941 ccagcgcttc taccgtggct ttcgcgccat tctgcaatag ctgttggtaa gcgtcggtaa
     3001 cggcttgcac aaattcgtgg ttcttcggca ggtcgttgcc aaagatagac tcgatggcca
     3061 gtagcccgcg aacgcgttct tccggcgtct gatattgctg atgaatcgcc tgatactgtg
     3121 caagcagcgg atcgacgaca tcaatggttt taccttgctc atcgacaccg ccgacataac
     3181 gcatccatcc ggcgacgccc agcgtcaggc ggcgatagtc atcgccctgt tgcaagtgca
     3241 gacgtaccgg gtccaacaga cgctgcggca gtttctgact gccatccatc gcgatctgcc
     3301 aggtgcggtg tttcaacgag gggttagtga aacgcgcaat caacaaattc gcataccctt
     3361 ccagatcggt gccttccggc attgacaacg tcggcgcttg ttcatcaagc atcagcgcca
     3421 gcgccgcgcg acggtaagcc gggttagtca tagtatcggc gatagtgtca tacccgccga
     3481 gataacccag ataggcgagg aaagagtgac tgccgttaag catacgcagc ttcatcatct
     3541 caaacggtac gacatctgca acgaattgcg cgccgacggt atcccagtcc gggcgaccat
     3601 tcacaaagtt atcttcgatg acccactggc ggaagggttc gcaggcgata gcgcaaggat
     3661 cataaacgcc caactggtcg gcaaccagtt gtagcgtctc ttcggtcgct gccggaacaa
     3721 tgcggtcaac catggtgcag gggaaggtca cattgtcggc aatccatgcg gcgagggcgg
     3781 catcgcgagc ttttgccagg ccgaggacgg cagccttcgc gacgtgacca ttctcgcgca
     3841 cgttatcgca cgacagcacg gtaaaagctt tcagtccttg ctcccggcgc atgtttagcg
     3901 cttcgacaat atagccaatg gcggatttag gctgctgtgg atgggcaaga tcgttttgga
     3961 tcagcgggtt attgacatca agctcgccgc tggcggggtc ggtgcagtag cctttttcgg
     4021 ttacggttaa ggagacgatg gcggtttccg ggcgcgccat tgccgccaga atccctgcat
     4081 gaccgtcgaa ttcagggtgt agcgcttctt tcattgaacc gataattttc agttcggtgc
     4141 tttctgcgcc gcgttctgca acggtgtaca gcagattttg cgctttcagg ttcgcgatca
     4201 gccgcgcgtc gttacccggc atcaggttca cttcacaaat gccccagtcg ctgtcgctct
     4261 tttccagtag atgatgggta aagagcgcct ggtgcgcgcg gtgaaacgcc ccgcagccca
     4321 gatgcacaat acgggatacc agacgtgatt tgtcccagtt tgggcgggcg acggaaacct
     4381 gggcggtggc gatattctgt tccattgcaa actcctgtca ttcgacgtct tcgcccgcga
     4441 tctccggggc gaggcatgtt gctattgcat tgagtagggg aaatcgcatg acgcgtcgcg
     4501 ccatgcgaaa gaaggttatt tgctaaagaa agcgcgctgg atagccagtt cgacgccgcg
     4561 gacttccgca agccctttca gacggccaat ggcggaataa cccggattcg ttttcttctt
     4621 cagatcgtcc agcatctgat gaccgtggtc cgggcgcatt gggatcagat cgtcgctacc
     4681 ttcggcttta cgacggtgct cttcttccac aatcgcttta acgacttcat acatatccac
     4741 atcgccgtgc aaatgggcgg cctcgtggaa ggtctttgga ttctcttcgc gcagcgtaga
     4801 gcgcagatgc gtaaagtaga tgcgcggacc aaattgcttg atcatatcaa ccagatcgtt
     4861 gtcggcgcgc acgccgtaag atccggtaca catggtgaag ccgttcgcca tgctattaac
     4921 ggtttcaacc atccattgca tgtcttcaat ggtagagaca atgcgcggca ggccgagaat
     4981 agggcgcggc ggatcgtcag ggtgaacggc catacgcacg ccaacctcgt cggcaaccgg
     5041 aataatggct ttcaggaaat aggcaaaatg ttcacgcagt tttgctttat cgatatcttt
     5101 atacgtcgcc aggtgttgac ggaactgatc cagcgtatag ccttcttccg cgccaggtaa
     5161 accggcaata atgttgcggg tcagacgtgc tttgtcttcc tcgctcatgg tggcgaaacg
     5221 ccgctctgcc tgagcaatct cttctgccgt atagtcggct tctgctcccg gacgcttcag
     5281 gatgtgcagt tcgaacgcgg cgaattcaat ctggtcaaaa cgcagcgctt ttgaaccatc
     5341 cggcaatacg tattccagat ccgtacgtgt ccagtccagc accggcataa agttatagca
     5401 aaccgtatag ataccgcatt gcgccaggtt acgcagcgtt tgctggtagt ttttgatcca
     5461 taaatcgtac tgaccggtgt gggttttgat gtcttcgtgg ataggtacgc tctctaccac
     5521 agaccactcc agacccgcct cttcaacgat tgctttacgt ttctggatct cgtctaccga
     5581 ccaaatttct ccattcggaa tatggtgtaa cgccgttacc acgccggttg cgccagcctg
     5641 gcgtacatct gacagcgtta ccgggtcgtt aggtccgtac cagcgccagg tttgtttcat
     5701 atctcgtttc ctcttcttgc gataacgtct tcgtggttga cccattgcca gccaacatcg
     5761 aaacgtgctt tgtaaacccg ttctgccccc taaattcaac caaaattttt ctcatgtcaa
     5821 ccttattatc taaattggct agccaaatca caaatatcat cattcacggt ctgccaattt
     5881 tatttatttg atctgcgtca atttttgctg ggtgaaaagc attcaccatt caacttgaaa
     5941 tgagttgatg tatttatttc aagaatatta agggcgggag ttgccgccag attttgaccg
     6001 gtccggatga gaaaatattg attggtcaac caatttttgt aatttcagtt ttcccgctac
     6061 aggtcagacg gcgcggagct aatgtttttt aacgaggctt tatcatgaag atgacaaaat
     6121 taagatggtg gattatcggc ctggtctgcg tggggaccat cgtaaactac ctgtcccgta
     6181 gctcgcttag cgttgcggcg ccagcgatga tgaaagaact ccattttgat gagcaacaat
     6241 attcctgggt ggtgagcgcc ttccagcttt gttacaccat tgcgcagccg atcaccggct
     6301 atttgatgga tgtcatcgga ctgaaaatcg gcttctttat ctttgccttg ttgtggtcgc
     6361 tgatcaacat ggcgcacgcg ctggccggcg gctggataag cctggcattt ctgcgtggtc
     6421 tgatggggct aaccgaagcg tcagcgattc cggccgggat taaagccagc gccgaatggt
     6481 tcccgacgaa agaacgtggt attgcggggg gcctgtttaa tatcggtact tcaattggcg
     6541 cgatgctggc gccgccgctg gtggtctggg cgatgctgac ctttgctgat agcggcatcg
     6601 gtactgaaat ggcgtttgtg attaccggtg ggatcggcgt gctgttcgcc atcacctggt
     6661 tcctgattta taactcgcca aataaacacc cgtggatcac ccacaaagag ctgcgttata
     6721 tcgaagacgg ccaggaaagc tatctccagg acgataataa aaaaccggcc gttaaagaga
     6781 tcgttaaaaa gcgtaacttc tgggcgttgg cgattacccg ttttcttgct gacccggcat
     6841 ggggaacgct gagtttctgg atgccgctgt atctgattaa cgtgatgcat ctgccgttaa
     6901 aagagatcgc catgtttgcc tggctgccgt tcctggcggc ggacttcggc tgcgttgcag
     6961 gcggtttcct ggcgaagttc ttcatggaaa agatgcacat gaccacgatc aatgcgcgtc
     7021 gttgtagctt taccatcggc gctgttttga tgatttcgat cggttttgtc agcattacga
     7081 ctaacccgta tgtcgccatt gcattgatga gtattggcgg ttttgcgcac cagacgctgt
     7141 ctaccgttgt gattaccatg agcgctgacc tgttcaagaa aaatgaggtc gcgacggttg
     7201 ccggtctggc aggatctgcg gcatggatgg gacagttaag cttcaacctg tttatggggg
     7261 cattggtcgc tattatcggt tacggcccgt tcttcattgc actcagtctg ttcgatatta
     7321 tcggcgccat catcctgtgg gtactgatta aagatccgga aaagcaccac ccgccaatga
     7381 cggaacagcc gctggcgtct caccgctaaa gctgtctcgg tttcacaggc ctgataagcg
     7441 aagcgctacc gggttctaac ggccaccttc gggtggccgt cttcattacc cttatcggta
     7501 aaaatacgcg ttggttttat accagcgcgt tatcatttag tttgcctgat tattttcaga
     7561 tgctgaaaat aatattgtgg taagggttat tgtttttcgc ctggattttt atcgactctc
     7621 tgtctcgctg cgatcatcga taaagtcccc tttatgtaaa taaaggttca atgcttctac
     7681 tcttttctcc atatattttg cgcagcttca caaaaaataa cctgatgtcg taatgtccac
     7741 tccctaatat tctccatgcg ctatacgtta atttaagttt aaatttcatg ctggggatat
     7801 cacgatgtca cgtaatttta ctgtttcagc ctgtcagtat attgttactg aaataaacac
     7861 ttttgaagat ttcataacaa aggtattgtt actgaaataa acacttttga agatttcata
     7921 acaaaggtaa ggatacttct taataaaagt cagggggctg atgccgttat cttcccggag
     7981 ctatttacca ttgagctatt tacactattg aaaaaatggc aagaaagacc catttcacac
     8041 ctaactttaa ttgatcagtt tacggatgcc tataagcagc tttttcaaca ggaagcgaaa
     8101 gaaagaggac agttcattat tgctggctct catctggagc agactggagc agatcgctat
     8161 gagaatgttg cgcatatatg gggacccgat ggcgaacatt atgctcacag taagacgcat
     8221 atcttcccgg ctgaacgggg ttggtatact caggaaggcg ataaaatggc tgtttttcaa
     8281 ctgccatttg caaaggtggg ttttaatatt tgttatgaag cagaaatacc ggagtgtgct
     8341 gcgacgctgg cggaacaggg tgctgagtta attttaacgc cttccgctac gtttactgaa
     8401 cagggatttt ggcgagtcag gcattgttgc cacgcacgtt gtattgaaaa tcaaatttat
     8461 cttgttcact gttgcctggg aggaaacccg ggcgggccac tgccaggctg ctgggcccga
     8521 agttcaattt taagcccctg tgatgtcgtg tggaaaaatc cacaaggtat tatcgcagag
     8581 gcgcacgtca atcaagagga tgtcatttca ggagaaatta acctcgatgt tctatatgaa
     8641 aatagacttg ggggggcagc aacaacgttc aaggacagac gcagaaaagc aggcatatat
     8701 aatatctggc catcacacat taaataacag aatgtgtccc ttctatgtat tagctggagg
     8761 tcgttatggg atatttaaaa ttacctgagg gtaaaaggat tgcggtcaat cttggtgtcg
     8821 atgtagatgc tcagtcttta tggctgggcg gatttaatcg accgtcgcca tcctttatgt
     8881 cacgaggaga gtttggcgca caagttggcg ttccaaggct tctgaaattg ttcaaagaaa
     8941 ataatatcaa aaccaccttt tttattcccg gacacactgt agacaccttc ccggaaatca
     9001 gtaaagcgat ttttgatgcc gggcatgaaa tcgctcacca tggctactat catgaaaacc
     9061 cgacgctggt gaatcgtgat acagaacgcc gacttatgga tctggcgttc gcctgttata
     9121 aaagacattt tggcatacgc cctgtgggat accgttctcc ctattgggat tatagcgaga
     9181 atacgctgga tcttctggag gaagccggtt ttctctatga cagtagcctg atggcgagag
     9241 atcttgtgcc ttaccatcct caacgttggc aggtgaattg ggaaacggga aatatcgcag
     9301 gcccggccag cgcgattctg gaaattcctg ttagctggta tctggatgat tttcccgcac
     9361 tggcgtatac cggtaaccag gaggggatga gcgatactga cggtgttctg cgacgctgga
     9421 aggatatttt tacctatgct tataaccatc aggaaaacgg tttatatgcg atggctcttc
     9481 atccgcagat aatcggtcat gggcatcata tgatgatgtt gtcacgtttg attgaacata
     9541 ttaaagggca tgatggcgta tggtttgcaa cctgtgaaga gatagccagt gtctgggtgg
     9601 atgacgaaga ggatcgacaa aaaatgctcc gtcctgatgt tcgtggcgta gcgccggttc
     9661 cggatgatta tggctggcca ggcaaatgat atcacctcat gacaatgtta atatcagtcg
     9721 ggtaacggat tacccgggca gaagttacct gtttgcccgc ttgttaatgc atattgtcca
     9781 tcagaaaggg agactatccc gggacgtata aaatcttttt tatttcggtc aaaacgttaa
     9841 tcaacgagaa tagtttgttt tttgatttaa atcatttttt gtgttcacag gaaaataag
//
LOCUS       DAJVKX010000151         9517 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.151, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000151 DAJVKX010000000
VERSION     DAJVKX010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9517
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.151"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            80..1045
                     /gene="dusB"
                     /locus_tag="OPY25_003889"
     CDS             80..1045
                     /gene="dusB"
                     /locus_tag="OPY25_003889"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCS0929383.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHVDEPGIRTVQIAGSDPVEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDLVKSILIGVVNAVDVPVTLKIRTGWAPEHRNCVEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPIIANGDITNPHKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCTHVRELHDFYGQAKGY
                     RIARKHVSWYLQEHAPDDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            1071..1367
                     /gene="fis"
                     /locus_tag="OPY25_003890"
     CDS             1071..1367
                     /gene="fis"
                     /locus_tag="OPY25_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HCS0929384.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            1453..2337
                     /gene="yhdJ"
                     /locus_tag="OPY25_003891"
     CDS             1453..2337
                     /gene="yhdJ"
                     /locus_tag="OPY25_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HCS0929385.1"
                     /translation="MKAECEPQYFGDESKKIIHGDALTELKKLPSESIDLIFADPPYN
                     IGKDFDGMVESWDEASFLAWLYECIDECHRVLKKHGTMYIMNSTENMPYIDLKCRTLF
                     TIKSRIVWSYDSSGVQAKKYFGSMYEPILMMVKNPKSYTFNRDAILVETTTGAKRALI
                     DYRKNPPQPYNQKKVPGNVWSFPRVRYLMDEYENHPTQKPSALLKRIILASSNPSDTV
                     LDPFAGSFTTGAVAAASGRKFIGIELNNEYVKMGLRRLSVTSHYSENELAKVKKRKTQ
                     NLSKKQRNVGINALSSEK"
     gene            2420..2584
                     /locus_tag="OPY25_003892"
     CDS             2420..2584
                     /locus_tag="OPY25_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HCS0929386.1"
                     /translation="MIRKYWWLVVFAVSVFLFDALLMQWIELMATEQDKCRNMDSVNP
                     LKLINCTDLE"
     gene            2735..4309
                     /locus_tag="OPY25_003893"
                     /pseudo
     CDS             2735..4309
                     /locus_tag="OPY25_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462298.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            4311..4736
                     /locus_tag="OPY25_003894"
                     /pseudo
     CDS             4311..4736
                     /locus_tag="OPY25_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462300.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
     gene            4748..7862
                     /locus_tag="OPY25_003895"
                     /pseudo
     CDS             4748..7862
                     /locus_tag="OPY25_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462301.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
     gene            8099..8320
                     /locus_tag="OPY25_003896"
     CDS             8099..8320
                     /locus_tag="OPY25_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929387.1"
                     /translation="MKRLIPVALLTTLLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            complement(9148..9263)
                     /gene="rrf"
                     /locus_tag="OPY25_003897"
     rRNA            complement(9148..9263)
                     /gene="rrf"
                     /locus_tag="OPY25_003897"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(9303..9378)
                     /locus_tag="OPY25_003898"
     tRNA            complement(9303..9378)
                     /locus_tag="OPY25_003898"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9343..9345),aa:Thr,seq:ggt)
BASE COUNT         2359 a         2350 c         2433 g         2375 t
ORIGIN      
        1 aaagtttggc ctttcatctc gtgcaaaaaa tgcgtaatat acgccgcctt gcagtcacag
       61 tatggtcatt tcttaactca tgcgcatcgg acaatatcag ctcagaaatc gcctgatcgc
      121 agcgcccatg gctggcatta ctgacagacc tttccggacg ctgtgctatg agatgggagc
      181 aggattgaca gtatccgaga tgatgtcttc taacccgcaa gtgtgggaaa gcgataaatc
      241 tcgtttacgg atggtgcacg ttgatgagcc aggaattcgc acggtgcaaa ttgccggtag
      301 cgaccctgtt gagatggccg atgccgcacg tattaacgtg gaaagcggcg cccagattat
      361 tgatatcaat atggggtgcc cggcgaagaa agtgaatcgt aagctggcag gttcagccct
      421 cttgcagtac ccggatttag tgaagtctat actcatcggg gtcgtaaacg cggtggacgt
      481 tcctgtgact ctcaagattc gcaccggctg ggcgccggaa caccgtaact gcgtagagat
      541 tgcccaactg gctgaagatt gtggtattca ggccctgacc atccatggcc gcacccgcgc
      601 ctgtttgttc aacggagaag ctgaatacga cagtattcgg gcagttaagc agaaagtttc
      661 cattccgatt atcgcgaatg gcgacattac taacccgcat aaagccagag ctgttctcga
      721 ctatacaggg gcggatgccc tgatgatagg ccgcgcagct cagggaagac cctggatctt
      781 tcgggaaatc cagcattatc tggacactgg ggagctgctt ccgccgctgc cgctggcaga
      841 ggtaaagcgc ttgctttgca cgcatgttcg ggaactgcat gacttttacg gtcaggcaaa
      901 agggtaccga atcgcgcgta aacacgtctc ctggtatctc caggaacacg ctccagacga
      961 ccagtttcgg cgcacattca acgctattga ggacgccagc gaacagctgg aggcgttgga
     1021 ggcatacttc gaaaattttg cgtaaacaga aataaagagc tgacagaact atgttcgaac
     1081 aacgcgtaaa ttctgacgta ctgaccgttt ctaccgttaa ctctcaggat caggtaaccc
     1141 aaaaacccct gcgtgactcg gttaaacagg cactgaagaa ctattttgct caactgaatg
     1201 gtcaggacgt taatgacctg tatgagctgg tactggctga agtagaacag cccctgttgg
     1261 acatggtgat gcaatacacc cgtggtaacc agacccgtgc tgctctgatg atgggcatca
     1321 accgtggtac gctgcgtaaa aaattaaaaa aatacggcat gaactaattt cgattagcta
     1381 actgcttgtt taaaaaggcg ctactcggca tggggaagcg ccttttttat acgcattaca
     1441 tggaatttgg tcatgaaagc ggaatgtgaa cctcagtact ttggcgatga atcgaagaag
     1501 attattcacg gtgacgcgct aacagaactt aaaaaactgc cttctgaaag cattgactta
     1561 atttttgccg atccgcctta caatatcgga aaagatttcg acggtatggt ggaatcctgg
     1621 gacgaagcgt cttttctggc ctggctgtat gaatgcattg acgagtgcca ccgcgtactg
     1681 aagaaacacg gcaccatgta catcatgaat agcacagaaa atatgccgta tatcgatctc
     1741 aaatgccgaa cgctttttac catcaaaagc cgtatcgtct ggtcctatga tagttccggg
     1801 gtgcaggcga aaaaatactt tggttctatg tatgaaccga tcctgatgat ggtaaaaaac
     1861 ccgaaaagct atacctttaa ccgtgacgcg attctggtcg agaccactac gggcgctaag
     1921 cgcgcgctaa tcgattatcg aaaaaacccg ccccaaccat acaatcagaa aaaagtgccg
     1981 ggcaacgtct ggtcatttcc tcgcgtacgt tatctgatgg atgaatatga aaaccatcct
     2041 acgcaaaagc ccagcgcgct gttaaaacgg atcatactgg cctcttctaa cccgagcgat
     2101 accgtattgg accctttcgc gggcagtttc accacaggcg ctgtcgcagc ggcgtcaggt
     2161 cgtaagttta tcggtattga actcaataat gagtacgtaa aaatggggct cagaagattg
     2221 agcgtcactt cgcattattc agaaaatgaa cttgcaaaag tcaaaaagag aaaaacacaa
     2281 aacctgtcca aaaagcagcg aaatgtcggg ataaacgcgc tatcttcaga gaagtaaaag
     2341 cattgtaagt ccgcttttca gcgtcaaaat ttcatgtata ttcccagcac gcatgggcat
     2401 gaatacacag gatttgacga tgatacgtaa gtattggtgg ctggttgttt ttgccgtctc
     2461 cgtttttctt tttgatgcgc ttttgatgca atggatcgaa ttgatggcga ctgaacagga
     2521 taagtgccga aacatggatt cggttaaccc tcttaaattg atcaattgta ccgatctgga
     2581 gtagcgaatc gggcgattta acctatgatt atttatcacc cggatttctt ttatccctta
     2641 taaaaacagg gaattaaaac acgttgagga taaaagaagg ggtgatactg tctcgtcctg
     2701 ttcttttcct gcataaccaa tgagctaatg atacatgccg gttagtgagt acaaccacat
     2761 ccttgtggcg gtttcatttg ctgtcgctat ttttgcgtcc tataccgcat taaatatggc
     2821 cggacgcgta gccggaagcg cccgatcaaa cgccagaata tggctaatgg gcggcggctt
     2881 cgcgctgggc gtcggtattt gggagatgca ttttgtcggg atgctggcga tggatcacgc
     2941 gatgaacatg cgcttcgatc cgttcctcac cggcctctcc atgctgatcg cgatcggctc
     3001 ctccctgttt gcgctatggc tggttagcgc tgaaaaactg cgcctgcgcc gtttactgcc
     3061 gggcgcgctg gtgatgggac tgggcatcag cgcaatgcat tataccggga tggcggcgct
     3121 gcaatttgct tccattatcg tttggaatag cgcgtgggtt gccctctcta tcattatcgc
     3181 gctactggcg tcctgcggcg cgctgtggct cacgttccgc ctgcgtaatg agggaacaga
     3241 tgtcgccctg aggcgagcag gcgccgcggt attaatgggg atagctatcg ccggcatgca
     3301 ttacgccggc atgaaggccg cacactttcc ccaaaactgg ccgatggaac atcgtggcgt
     3361 cgatagcaac tggctggctg ttcttgtcag cgtggtcgcg ctgactatcc tgggtattac
     3421 tctgctggtt tctttatttg acgcccggct tcaggcccgt accgcactac ttgcctcttc
     3481 gctggcgcag gcgaaccagg aactggcgca gttggcgctg catgatacgc tcacccgttt
     3541 accaaaccgg gtactccttg aggatcgtct ggaacaggcc atcagcaaag cgaatcggga
     3601 aagcacgtct ttcgcgctac tgtttatgga tctggatggc tttaaagccg ttaatgacgc
     3661 ttatggtcat gatattggcg ataagctact ggtggcggtc acgcatcgtc tgaaccaacc
     3721 gctgagcggg cagtttaccc tggcgcggat tggcggcgac gaatttgtgc tgcttgcgga
     3781 agtcagcgcg cctgacgaag cggcttccct tgccagcgcg ctggtacatt cgatagatgc
     3841 gccctttacg atagatccgt acgaactggt tgtcaccctt agcgtgggaa tagcgctcta
     3901 tccgctggac ggaaaaaacg aacgggaact gatgttcaac gccgatgccg cgatgtacca
     3961 cacgaagcat acggggcgta acggatacca tttctttcag ccatcaatga atatgctggc
     4021 gcaaacccaa cttcagctaa tgaatgacct gtggctggcg ctggaaagac aagagctcag
     4081 gctggtgtat cagcctaaat ttcaggctcc tgccggcccc attgtaggat ttgaggccct
     4141 gttgcgctgg tatcatccaa aacaaggcgt actgaatcct gaccagtttt taccgctggc
     4201 ggaaaaaacg ggtcttatcg tcactatcgg tagctgggtg atagacgagg cgtgtcgaca
     4261 gctccgcgag tggcacttac agggatacgc cttatggtca gtggcggtaa ctggtaatgg
     4321 aaaatggtca ggtctacccg attaaaggca cgctgcaatt ttccgacgtt accgtagatg
     4381 aaagcaccgg ctctatcacg ctcagggcgg tgttccctaa cccgcaacac agtctgcttc
     4441 ccggtatgtt tgttcgcgcc cgcatcgatg aaggcgtcca gcccaatgcc atccttgtcc
     4501 cccagcaggg cgtgacccgc acgccgcgcg gcgacgcaat ggtgatggtg gttaacgata
     4561 aaagtcaggt cgaagcccgc aatgtcgtgg cgacgcaggc tattggcgat aaatggctca
     4621 tcagcgaagg gttaaaaccg ggcgataagg tcatcgtcag cggcttacaa aaagcgcgac
     4681 cgggcgtcca ggtgaaagcc actaccgatg ctcctgcagc gaaaacggcg caataaggta
     4741 accgtacatg gcaaactttt ttattagacg tcctattttc gcctgggttc tggccattat
     4801 cctgatgatg gctggcgcac tggcaataat gcaacttccc gttgcgcagt atccaaccat
     4861 tgcgccgcca gcggtttcta tttctgcaac ctatcctggc gcggatgcgc agacggtaca
     4921 ggatacggtt actcaggtta tcgaacaaaa tatgaacggt atcgataacc tgatgtatat
     4981 gtcctctacc agcgactctg ctggtagcgt gaccatcact ctgaccttcc agtccggaac
     5041 cgatccggat atcgcgcagg ttcaggtgca aaataaattg cagctcgcca cgcctttact
     5101 gccgcaagaa gtccagcagc aggggattag cgttgaaaaa tccagcagca gctttttgat
     5161 ggtcgccggg ttcgtctcgg ataatccgaa cactacccag gacgacatct ctgactatgt
     5221 cgcctctaac attaaggatt ctatcagccg tctgaacggc gtgggcgacg ttcagctatt
     5281 tggcgcacag tacgccatgc gtatctggct ggatgcgaat ctgctaaata aataccagct
     5341 cacgccagtt gacgtcatca accagttaaa agtacagaac gaccagattg cggcaggcca
     5401 actgggcggt acgccagcat taccgggcca gcagcttaac gcctcaatca tcgcccaaac
     5461 gcgtctgaaa gatccggaag agttcggcaa agttacgttg cgcgtcaata ccgacggctc
     5521 tgtcgtccat ctcaaagatg tcgcgcgtat tgagcttggc ggtgaaaact ataacgttgt
     5581 agcgcgcatt aacggtaaac cggcctccgg tctcggtatt aaactggcga ccggcgctaa
     5641 cgcgctggat accgcaaccg caatcaaagc gaaactggcg gaactgcagc ctttcttccc
     5701 tcagggaatg aaggtggttt atccttatga cactacgccc ttcgtaaaaa tatctatcca
     5761 cgaagtggta aaaacgctat ttgaagcgat tattctggtg ttcctggtaa tgtatctgtt
     5821 cttacagaat atccgggcaa ccctgattcc taccatcgct gttcctgtcg tgttgctagg
     5881 cacttttgcg gtactcgccg cctttggcta ttccatcaat accctgacga tgttcggcat
     5941 ggtactggcg atagggctgc tggttgacgg tgcgatagtg gtcgtagaaa acgttgaacg
     6001 tgtaatgatg gaggataacc tttctcccag agaggcgacg gaaaaatcca tgtcgcagat
     6061 ccagggagcg ctggtcggta tcgcgatggt actgtctgcg gtatttatcc cgatggcctt
     6121 ttttggcggc tcgaccgggg caatttatcg ccagttctct attactattg tttcagcaat
     6181 ggcgctatcc gttctggttg cgttgattct gacgccagcg ctatgcgcta cgctgcttaa
     6241 acccgtatct gctgaacatc acgagaaaaa aagcggcttc tttggctggt tcaataccag
     6301 gtttgaccac agcgttaacc actatactaa cagcgtaagc ggtatcgtgc gtaatacggg
     6361 tcgctatctc attatctatc tacttattgt agtcggaatg gcggttctgt ttttacgcct
     6421 cccgacctcc ttcctgccgg aagaagatca gggggtattc ctgactatga ttcagctccc
     6481 ctctggcgct acgcaagaac gtacgcagaa agtgctggat caagtcactc attactacct
     6541 gaataatgaa aaagcgaacg tcgaaagcgt gtttaccgta aacggcttta gctttagcgg
     6601 tcagggacaa aactcaggga tggcatttgt cagccttaaa ccctgggaag agcgtaacgg
     6661 tgaagaaaat agcgtcgaag ccgttatcgc cagagcgaca cgcgccttta gccagattcg
     6721 cgacgggttg gtgttcccct tcaacatgcc ggcaattgtc gagttaggta ccgcgacagg
     6781 tttcgacttc gaactgattg atcagggagg actcggtcat gatgcgttaa caaaagcgcg
     6841 taatcaactc ctgggtatgg tcgcgaagca tcctgatcta ttagtgcgcg tacgcccgaa
     6901 cgggctggaa gacacgccac agttcaagct ggatgtcgat caagaaaaag cacaggcgct
     6961 cggcgtttcg ctgtctgata tcaacgaaac catctccgcg gcgttgggcg gctattacgt
     7021 taacgacttt atcgatcgcg gacgagtgaa aaaagtatac gttcaggctg acgctcagtt
     7081 ccgtatgctg ccggaagata tcaacaatct ttatgtacgc agcgccaatg gcgagatggt
     7141 gcccttctct acctttagct cagcacggtg gatttatggt tcgccacgcc tggaacgcta
     7201 taacgggatg ccgtcaatgg aactgctcgg tgaagcagcg cccggacgaa gtaccggtga
     7261 agccatgtcg ttaatggaaa acctggcttc acagctgcca aacggtattg gctatgactg
     7321 gacaggtatg tcgtatcagg aacggttgtc aggtaaccag gcgccggcgc tgtacgcaat
     7381 ctcactcatt gtcgttttcc tctgccttgc cgctctgtat gaaagctggt caattccgtt
     7441 ctcggtaatg ctggtcgtac cgctccggcg tggttggcgc tctgcttgca gcgtcattgc
     7501 gcggcctgaa taatgacgtt tacttccagg ttggcttgtt aaccactatt ggcctttctg
     7561 ctaaaaacgc catcctgatt gttgagttcg ccaaagatct catggaaaaa gaaggacgtg
     7621 gattgattga agcgacgctg gaagcatccc gtatgcgttt acgtcctatt ctaatgacct
     7681 cgctggcctt tattctcggg gtaatgccgt tagttatcag tcgtggcgca ggtagtgggg
     7741 cacagaacgc agtaggcaca ggggttatgg ggggaatgtt aaccgcaacc ttattagcta
     7801 tcttcttcgt gccagtattc ttcgttgttg taaaacgccg atttaatcgc catcatgatt
     7861 aaccagtaaa cagaggcgtc ttcggacgcc ttttaaacgg tacgtcttta tctccgctat
     7921 tcccccctct ccgcttacct ctgcattctc catagttttt acaattcaca tgaattgaga
     7981 tgattcctca tgtcagccat tttttctgtg gtggtaaaat aactctcgtt ttcacagcgg
     8041 ttagagccag catttacgtt gctgtacttt gcgaaacgct gattaatgag gtaacaccat
     8101 gaaaagacta attccagttg cattgcttac caccttattg gcaggttgtg cacatgattc
     8161 tccctgcgta ccggtttatg acgatcaagg gcggctggtt cataccaata catgtatgaa
     8221 aggtacaacg caggataact gggagacagc aggcgctatc gctggcggcg ctgcggcggt
     8281 agcagggttg acgatgggta tcattgcgct ttctaaatga tacatgcagg cgcggcaatg
     8341 ccgcgctttc agtaataata taaaggtcgt aaggatactc agcgacgtaa tctattcagc
     8401 ctatccccga aagttaacac gataaaacgc tctcttttct tactcgccca tcccgatggt
     8461 atttattcta ttccttgtcc gatgcagaca aaattgtagc ttgatagcat cgtaagccgc
     8521 attacaaaca ggctttatac agtaagactt agagcgtggt cattaggcgt aattattaca
     8581 gacagtctgg atataaaccg gaacatacac gtaatacatg aggattttga gcactgtccc
     8641 agggccaaac tggcaaataa aatagcctaa tgggccagat tcttagtcct cagcgaatat
     8701 ctctattgct tattagaggc gtaagtaaaa gccgtttgta catctacttc agcacggttc
     8761 acattcgatg gttcaggcgg atatatggcg ggaaatcacg tttactaaaa cggtttttat
     8821 ccactctacg aagatgttat atacccaaaa taattcgagt tgcttaaagg cggcaaggga
     8881 gtgagtcccc aggagcatag ataactatgt gactggggtg agcgacaaat ctgccgggag
     8941 cagatttaaa cgtcgcgtgc gacggcccgt cagggcgagg cccatgaatg ggccgagtaa
     9001 tccgtagcca acacataagc gacttgaagt atgaaaggta taaaccaaat ataaaacgcg
     9061 tcggcgtcat tatccgataa ctttttccat agagagataa atgcaaaaag gcccaatctt
     9121 tcgattgggc cttttgcttt atttgatgtc tggcagttcc ctactctcgc atggggagac
     9181 cccacactac catcggcgct acggcgtttc acttctgagt tcggcatggg gtcaggtggg
     9241 accaccgcgc tactgccgcc agacaaattc tttttcaaat gccgaacttt aaccgtatta
     9301 agtggtgctg atacccagag tcgaactggg gacctcaccc ttaccaaggg tgcgctctac
     9361 caactgagcc atatcagcac actaaatttg atgcctggca gtttatgaat cacttcgtga
     9421 ttcacccttc gggccgttgc ttcgcaacgt tcaaaagatt cgcttttgtc ctactctctg
     9481 tcgagtagtg aactgccccg aaagttaatg ccatact
//
LOCUS       DAJVKX010000152         9381 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.152, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000152 DAJVKX010000000
VERSION     DAJVKX010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9381
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.152"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..1620
                     /locus_tag="OPY25_003899"
     CDS             <1..1620
                     /locus_tag="OPY25_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCS0929388.1"
                     /translation="DVHVRIVPKENGQEIAYKVNNKYLLTYGGIPVFGLYPDYVNTVE
                     VEYTRIQGSKTENIKESYKMYAPPAYSESAGTKEEQSALFTIDVKKVSPEFKDRLYLL
                     NNTKDKSGNGTRTVWNNPTGGALEWNFTTANAIIDTSGDIRWFMNPSSIYDLKSIYRA
                     GVMMGFKQNQDGALSWGYGQRYVKYDIMGREIFNRRLPDNYNDFSHSMDNAPNGHYFL
                     RVASSNYKRPDGKNVRTVRDVIAEVDQNGVVVDEWRLFDILDPYRDVIMKTLDQGAVC
                     LNIDASQSGHTLSEEDLAALDSSDKFGDIVGSGAGRNWAHVNSVDYDSEDDSIIISFR
                     HQSAIIKIGRDKKVKWILGTPAGWKAPFNAAILTPVDSKGQKISCQESGCEGDFDWTW
                     TQHTAFKIDSKSKGDILYLSAFDNGDGRGLEQPAMQSMKYSRSVIYKIDQKNKTVQQI
                     WQYGKERGNEWFSPVTSITEYQTDKNSVFVYSATAGGEFDLSVGAFTSLPNPYLEEFR
                     WGEKEPAVEMQIHGARGYQAMPFSLTKALTE"
     gene            complement(1817..2980)
                     /gene="fadA"
                     /locus_tag="OPY25_003900"
     CDS             complement(1817..2980)
                     /gene="fadA"
                     /locus_tag="OPY25_003900"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HCS0929389.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPS
                     LTAATLDDIYWGCVQQTLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQVCLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLSRLHGI
                     SREMQDQFAARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LSTLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLINLMERKDAQFGLATMCIGLGQGIATVFERV"
     gene            complement(2990..5179)
                     /gene="fadB"
                     /locus_tag="OPY25_003901"
     CDS             complement(2990..5179)
                     /gene="fadB"
                     /locus_tag="OPY25_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HCS0929390.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGQALE
                     VLEKQHDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTLAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRLPRMLGA
                     DSALEIIAAGKDVGAEHALKIGLVDGVVKQEKLIEGAIAVLRQAITGDLDWRAKRQPK
                     LEPLKLSKIEAAMSFTIAKGMVAQTAGKHYPAPMTAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDIETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVIMKDINDKSLNLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDVVVEAVVENPKVKKAVLAETEQKVRPETVLASNTSTIPIGELASALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNNCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKVDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     EYRDAIDALFDASRFGQKNGLGFWRYKEDSKGKPKKEEDAAVDDLLASVSQTKRDFSD
                     DEIIARMMIPMINEVVRCLEEGIIASPAEADMALVYGLGFPPFHGGAFRWLDTQGSAK
                     YLDMAQQYQHLGPLYEVPEGLRDKTRHNEPYYPPVEPARPVGSLKTA"
     gene            5369..6700
                     /gene="pepQ"
                     /locus_tag="OPY25_003902"
     CDS             5369..6700
                     /gene="pepQ"
                     /locus_tag="OPY25_003902"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HCS0929391.1"
                     /translation="MESLAALYKNHIVTLQERTRDVLARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     EVEVVALPKADGIGSQLPAARGNIGYIGPVPERALQLDIAASNINPKGVIDYLHYYRA
                     YKTDYELACMREAQKMAVSGHRAAEEAFRSGMSEFDINLAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPSEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAHLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPSKYPYLRCTRVLQPRMVLTIEPGIYFIES
                     LLAPWREGPFSKHFNWQKIEALKPFGGIRIEDNVVIHENGVENMTRDLKLA"
     gene            6700..7314
                     /locus_tag="OPY25_003903"
     CDS             6700..7314
                     /locus_tag="OPY25_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HCS0929392.1"
                     /translation="MDSWLIPAAPVTVVEEIKKSRFITLLAHTDGVEAAKAFVELVRA
                     EHPDARHHCAAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLATQRKTPLTEYTLQCEYGQLAGIEALLGQFAG
                     KIVSSDYQASVRLRVALPFAHVNAFSTKLADFSRGSLQLLAIEE"
     gene            7353..8804
                     /gene="trkH"
                     /locus_tag="OPY25_003904"
     CDS             7353..8804
                     /gene="trkH"
                     /locus_tag="OPY25_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HCS0929393.1"
                     /translation="MHFRAITRIVGLLVILFSGTMILPGLVALIYRDGAGGAFTQTFF
                     VALAIGSILWWPNRREKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPVLGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMPAFDAIGHSFSTI
                     AIGGFSTHDASVGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQLTLVVICTLVLWFHNIYDSALTTLNQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFASM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            8816..9361
                     /gene="hemG"
                     /locus_tag="OPY25_003905"
     CDS             8816..9361
                     /gene="hemG"
                     /locus_tag="OPY25_003905"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HCS0929394.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKEMGIWADVVNLHRAEEPD
                     WDSYDRVVIGASIRYGHYHSAFQEFVKKYATRLNGMPSAFYSVNLVARKAEKRTPQTN
                     SYARKFLMSSPWRPDYCAVIAGALRYPRYRWYDRLMIKLIMKMSGGETDTSKEVVYTD
                     WEQVAHFAREIAHLTNKSSAK"
BASE COUNT         2140 a         2421 c         2545 g         2275 t
ORIGIN      
        1 gacgtgcatg tgcggattgt acccaaagaa aatggccagg agatcgcgta taaagttaat
       61 aataaatacc ttttaacgta tggcggtatt cccgtctttg gtctttaccc ggattatgtc
      121 aataccgttg aagttgaata tacaagaatc cagggtagta aaaccgaaaa tataaaagaa
      181 agctataaaa tgtatgcacc gcctgcttat agtgaatcag cgggtacaaa agaagaacaa
      241 tcagcactct ttactatcga tgttaaaaag gtttccccag aatttaaaga tcgcttgtat
      301 cttttgaata atacgaaaga taagtctggg aatggaacgc gtactgtctg gaacaaccct
      361 actgggggtg cattagaatg gaacttcact acagctaacg ctattatcga cacctccggt
      421 gatattcgtt ggtttatgaa tccaagttca atttatgatt taaagtcaat ttatcgtgct
      481 ggcgttatga tgggctttaa acaaaaccag gatggcgcac tatcgtgggg ctacggtcag
      541 cgttatgtga aatacgatat catggggcgt gaaatcttca accgccgcct gccggataat
      601 tataacgatt tttcacactc aatggataac gcgcccaacg gtcactactt cctgcgtgta
      661 gccagctcta actataaacg tcctgatggg aaaaatgttc gtaccgtgcg tgatgtgatt
      721 gccgaagttg atcagaacgg cgtggtagtg gatgaatggc gtctgtttga tatcctcgat
      781 ccttatcgtg atgtgataat gaaaaccctc gatcagggcg cagtgtgcct gaatatcgac
      841 gccagccagt ccggccatac gttgagcgaa gaagatctgg cggcgctgga ctcctccgac
      901 aaattcgggg atatcgtggg tagtggggct ggccgcaact gggcgcatgt caacagcgtc
      961 gactatgaca gtgaagatga ttccatcatc atcagcttcc gccaccagag tgcgattatc
     1021 aaaatcggtc gcgataagaa agtgaagtgg atacttggta cgcctgctgg ctggaaagcg
     1081 ccatttaatg ccgcaattct gacgcctgtg gatagcaaag gccaaaaaat ttcctgccag
     1141 gaaagtggct gtgagggtga cttcgactgg acatggacgc aacatacggc ctttaaaatt
     1201 gatagtaaga gtaaaggcga tatcttatac ctttccgctt tcgacaatgg tgatggccgc
     1261 ggcttagaac agcctgctat gcagagtatg aaatacagcc gctccgtgat ttacaaaatc
     1321 gaccagaaaa acaagacagt ccaacagatc tggcaatacg gtaaagagcg cgggaacgag
     1381 tggtttagcc cggtaacctc tatcaccgag taccagactg acaagaattc tgtgttcgtg
     1441 tattccgcaa cagcaggtgg tgagtttgat ttgtcggtag gcgcatttac cagcttgcct
     1501 aacccgtatc tggaagagtt cagatgggga gaaaaagagc ctgcggtcga aatgcaaata
     1561 catggtgcgc gtggatatca ggctatgcca tttagcctga ccaaagcgct tactgagtag
     1621 agcaggccac acggtgaaaa aacccgcccc tgacgggcgg gaaaaacggc aactaaactg
     1681 ttccccgtca taactcacgc tgcctctttg ttggctgcct ttgttcaccc cgggcatata
     1741 gttatctatg ttcccgggga ttcgctcagt tgccgccgcg ctgcaacgtg aattatttag
     1801 gggacattat ctttaattaa acccgctcaa acaccgtggc gatgccctga cccagaccaa
     1861 tacacatcgt cgccagacca aactgcgcgt ctttgcgctc catcaggttg ataagcgtgg
     1921 tgctgatacg tgctccggag cagccgagcg gatggccaag cgcgatcgcg ccgccgttga
     1981 ggttgatctt ctcgtctatc tgctccatca atcccagatc cttaatgcat ggcaggatct
     2041 gtgcggcaaa cgcttcgttc atctcaaaca catcgatatc gctggccgac agtcccgctt
     2101 ttttcaacgc cagttttgac gccggaaccg gcccgtaacc cataattgac ggatcacaac
     2161 ccaccactgc cattgagcga atacgggcgc gaggtttcag acccagctca cgggcacgac
     2221 tttcgctcat taccagcatg gcggctgcgc catcggaaag cgcggatgag gtgcccgccg
     2281 tgaccgtgcc actaaccgga tcaaatgccg gacgcagcgt tgatagcgct tcgaccgtgg
     2341 tttccgggcg gatcacttca tcgtagttaa actgcttcaa cacgccgtct gcatcatgac
     2401 cgccagtcgg gataatctcc gttttgaatg cgccagactg ggtggcggcc caggcgcgag
     2461 cgtgagaacg cgcggcgaac tggtcctgca tttcccggct aatgccgtgc aggcgggaga
     2521 gcatttccgc cgttagcccc atcatccctg ctgctttggc gacgttgcgg ctcagacccg
     2581 ggtgaaaatc cacgccgtgg ctcatcggca cgtgccccat atgctccacg ccgccaacca
     2641 gacaaacctg cgcatcgccg gtcatgatca ttcgcgctgc atcgtgtaac gcctgcatcg
     2701 aggaaccaca cagacggttg acggtgaccg ccggtaccga atggggaatt tctgccagca
     2761 gcgcggcgtt acgggcaatg ttgaagcctt gctccagcgt ttgttgtacg cagccccagt
     2821 aaatatcatc gagggtcgcc gctgtaagcg acggattacg cgccagcagg ctacgcatta
     2881 agtgggcgga gagatcttct gcccgcacgt tgcgaaacgc gccgcccttc gaacggccca
     2941 tcggggtgcg aatggcatcg acaatgacaa cctgttccat tgtgactcct taagccgttt
     3001 tcagagaacc aaccggacgg gctggttcaa ccgggggata atacggttcg ttatggcgcg
     3061 ttttatcacg cagcccttcc ggcacttcat acagcgggcc gaggtgttga tactgctgcg
     3121 ccatatcaag atatttcgcg ctgccctgtg tatccagcca gcggaatgcg ccgccgtgga
     3181 acggagggaa gcccaggccg tagaccagcg ccatatcggc ttccgccggg cttgcgataa
     3241 tgccttcttc cagacagcga accacttcgt taatcatcgg gatcatcata cgggcgatta
     3301 tctcgtcgtc gctgaagtcg cgtttcgtct gactgacgct tgccagcagg tcatccaccg
     3361 cagcatcttc ttctttcttc ggcttaccct tgctgtcttc tttatagcgc cagaagccca
     3421 gaccgttttt ttgcccaaaa cggctggcgt caaacaatgc gtcgatcgcg tcgcgatact
     3481 ctttctgcat ccgttgtggg aagcctgccg ccattaccgc ctgcgcgtgg tgggcggtat
     3541 caatacccac cacgtcgagc agataggccg ggcccatcgg ccagccgaac tgtttttcca
     3601 tcactttatc gactttgcgg aaatccgcgc cgtcgcgcag cagttgactg aaaccggcga
     3661 aataggggaa cagcacgcgg ttaacaaaga agccggggca gttgttgact acaatcggtg
     3721 tcttgcccat tttgctggcc caggcgacga ctttggcaat ggtttcgtct gaactcttct
     3781 cgccgcgaat gatttcaacc agcggcatcc ggtgtaccgg gttgaagaag tgcattccgc
     3841 aaaagttttc cggacgttcc agggcgcttg ccagttcgcc aattgggatg gtggaggtat
     3901 ttgaggccag cacggtttct gggcgcactt tctgctcggt ttccgccagt accgcttttt
     3961 tgactttcgg attttcgact accgcttcga caacaacatc tacgcgatcg aaaccggcat
     4021 aatcgagagt cgggtggatg gtcgaaatga cgcccgccag cttcagaccg tcgatcttgc
     4081 cgcgctccag ctgtttgttc agcagcttgg ccgcttcggt catgccgagg ttcaacgatt
     4141 tatcgttgat atctttcatg atgaccggta cgcctttcca ggccgactgg taagcgatac
     4201 cgccgcccat aatgcccgcg cccagtacgg ctgcctgttt cggcgtctca atatctttgg
     4261 tcagcttttt ggctttacct tttacatatt gatcgttgag gaagataccg accagcgcac
     4321 gagcctcatt ggtatgcgcc agcggaacaa agcttttatt ttccagattc agcgcttctt
     4381 cacgaccaaa acgcgcggcg gcttcaatgg ttttcactgc ggtcatcggc gccggataat
     4441 gtttacccgc cgtttgtgcg accatgcctt tagcgatggt aaagctcatc gccgcttcaa
     4501 ttttgctgag tttcaacggt tccagtttcg gctggcgttt agctctccag tcgagatcgc
     4561 cggtaatggc ctggcgtaac accgctatcg cgccttcaat tagcttctct tgtttgacca
     4621 cgccgtccac aaggccgatt ttcagcgcgt gctcagcacc gacatcttta cctgccgcga
     4681 taatctccag cgcgctgtcc gcgcccagca tacgcggcag acgaacggag ccgccgaaac
     4741 ccggcatgat gcccagttta gtttccggca gaccgatacg gaggtctggc gtcgccagac
     4801 ggtaatcggt cgccagcacg cattcacacc cgccgcccag cgcatagccg tttacggcgg
     4861 caagggtcgg tacgggtaaa tcttccagac ggttaaagac gctattagcg aaatgcagcc
     4921 attggcttaa ctgctcttcg gggacgagga acagtgaaag aaattcggtg atgtccgcgc
     4981 cgacaataaa ggccgcttta ttagagcgca gcagcagccc ttttaaatcg tgttgctttt
     5041 ccagcacctc aagcgcctgg ccgaggctgg cgacggttgc ggtgtcgagt ttattgaccg
     5101 agcctggagc atcgaacacc agttcggcga tgccatcttc cagccagtcg aggtacaggg
     5161 tgtcgccttt ataaagcatg tcagtctcct gaatccacaa ggtgatctgg tcgtatcaga
     5221 tgaagcgaag tgtgtatttt gtgttaataa aatgcaaata aatgattaaa gaaatgccga
     5281 tgtgatcacg ctcggcagag atcacgctct cgtggggcga tgtgctaaga tgcggaaact
     5341 tgaggtcaaa aaaacagaag ggtaaaaaat ggaatcactg gccgcgctct ataaaaatca
     5401 tattgttacc ttacaagaac ggacgcgcga tgttctggcg cgctttaagc tggatgcgtt
     5461 acttattcat tccggcgagc ttttcaacgt ctttctcgac gatcaccctt atccgtttaa
     5521 ggtcaatccg cagtttaaag cgtgggtgcc ggtaactcag gttccaaatt gctggctgct
     5581 ggtcgatggc gtcaacaaac ccaaattgtg gttttatctg ccggtcgatt actggcataa
     5641 cgttgaaccg ctgccaacgt cattctggac agaagaagtc gaggtcgtcg ccttaccgaa
     5701 agcggatggc atcggcagcc aacttcctgc cgcgcgtggc aatatcggct atatcggccc
     5761 ggttcctgag cgcgcgctac aattggatat cgccgccagc aacatcaacc cgaaaggtgt
     5821 tatcgactat ctgcattact accgcgccta taaaacggat tatgaactgg cctgtatgcg
     5881 cgaagcgcag aaaatggcgg tgagcggtca tcgggcggcg gaagaggcct tccgttccgg
     5941 catgagcgag tttgacatca acctggcgta cctgaccgcc acgggacatc gcgataccga
     6001 tgttccgtac agcaacattg tggcgctgaa cgaacatgcc gccgtgctgc attacacgaa
     6061 actggatcat caggcaccgt ctgaaatgcg cagtttcctg ctggatgcgg gcgcggaata
     6121 caacggctac gcggcggatc tgacgcggac ctggtcggcg aaaagcgata acgactacgc
     6181 ccacctggtg aaagatgtta acgacgaaca gttggcgctg atcgctacca tgaaggcggg
     6241 cgttagctat gtggattatc atattcagtt ccatcagcgc atcgcaaagc tgctgcgtaa
     6301 gcatcaaatc attaccgaca tgagtgaaga ggcgatggtg gaaaatgatc tcaccgggcc
     6361 gtttatgccg cacggtattg gtcatccgtt gggtctgcag gtacacgatg tggccgggtt
     6421 tatgcaggat gattccggta cgcatctcgc cgcgccgtcc aaatacccgt atctgcgctg
     6481 cacgcgtgtg ttacagccgc gaatggtgtt gaccatcgaa ccggggattt acttcatcga
     6541 atcgctgtta gcgccgtggc gcgaagggcc attcagcaag cacttcaact ggcagaaaat
     6601 tgaagcgctc aagcctttcg gcggtattcg cattgaagat aacgtggtca tccacgaaaa
     6661 cggcgtggaa aacatgacgc gggatttaaa actggcgtaa tggacagttg gttaatccct
     6721 gcagcgccgg tcaccgttgt tgaagagatc aaaaaaagcc gctttattac gctattggcg
     6781 cataccgatg gcgtagaggc ggcgaaagcg tttgttgagt tagtcagagc tgagcaccct
     6841 gatgcgcgcc accattgtgc ggcgtgggtg gcgggtgcgc cggacgactc acaacaactg
     6901 ggcttttcag acgacggcga gccggcggga acggcaggca agccgatgct tgcgcaattg
     6961 atgggcagcg gcgtcggaga aattactgcc gtcgtcgtgc gctactatgg tggtattctg
     7021 ctgggtacgg gcgggctggt aaaagcctat ggcggcggtg tgaatcaggc attacgtcag
     7081 cttgccacac aacgcaagac gccattaacc gaatatactt tgcagtgtga gtacggtcag
     7141 ttggccggaa tcgaagcatt attaggacag tttgccggga agatcgtttc cagcgattat
     7201 caggcgtctg ttcggctcag ggtggcgctt ccttttgctc atgtgaatgc attttccaca
     7261 aaactggcgg attttagccg tggttcattg caattgttag cgattgaaga ataatcccca
     7321 cctcattttt aagaataaag gaagcggcag agatgcattt tcgcgccatt acccgaatcg
     7381 ttggactact ggttatctta ttttcgggga caatgattct cccgggactg gtagcgctaa
     7441 tatatcgtga tggcgcagga ggagcgttca cgcagacctt ttttgtcgcg ctggcgatcg
     7501 gttccatact gtggtggcca aatcgtaggg aaaagggcga gctgaaatcc cgcgaaggat
     7561 ttcttatcgt ggtgctgttc tggaccgtgc tgggcagcgt gggtgcgctg ccgtttattt
     7621 tctcggaaag cccaaacctc accattaccg atgctttttt tgaatcgttc tccgggttaa
     7681 ccaccacggg cgccactacg ctggtggggc tggattcatt accgcacgcc attctctttt
     7741 atcgtcagat gctgcaatgg tttggcggta tggggatcat tgtgctggcg gtggcgattc
     7801 tccctgtcct cggcgtcggg gggatgcagc tctatcgggc agaaatgccg gggccgctca
     7861 aagataacaa aatgcgcccg cgtattgccg agacggcgaa aacgctgtgg cttatctatg
     7921 tcttgctaac ggtagcctgc gcgctggcgc tatggtttgc agggatgccc gcgtttgacg
     7981 ctatcggaca cagcttctcc actatcgcta tcggcggctt ctcaacgcat gacgccagcg
     8041 taggctattt tgatagtccc actattaata ccatcatcgc tattttcctg ctgatctccg
     8101 gttgtaacta tggcctgcat ttctctttat taagcgggcg tagcctgaag gtatactggc
     8161 gcgatccgga attccgcatg ttcatcggcg tacagttgac gctggtggtg atctgcacgc
     8221 tggtactgtg gttccataat atctacgact cggcgctgac aacgctaaat caggcgttct
     8281 tccaggttgt gtcgatggcg acaacggcag ggtttaccac ggacagcatt gcgcgctggc
     8341 cgctgttttt gcccgtcttg ctgctatgtt ccgcgtttat tggcggttgc gccgggtcaa
     8401 cgggcggggg gttaaaggtc atccgtattc tgttgttatt taaacagggg aaccgcgaac
     8461 tcaaacgtct ggtgcatccg aatgccgttt acagtattaa gctggggaac cgggcgctgc
     8521 cagagcgtat tctggaagcc gtctggggat tcttttctgc ctacgcgctg gtatttatcg
     8581 tcagtatgct ggccattatc gctacaggcg tagatgattt ctcggctttc gcctcggtag
     8641 tggctacgct taataacctg ggaccggggc tgggggtggt tgctgataac ttcgccagta
     8701 tgaatccggt tgcgaaatgg atactcatcg ccaacatgct atttggtcgt ctggaagtat
     8761 tcactttgct ggtacttttt accccgactt tctggcgtga ataatggagt aacacgtgaa
     8821 aacattgatt cttttctcta cccgggacgg acaaacgcgc gaaattgcct cttatctggc
     8881 ttctgaactc aaagagatgg ggatctgggc cgatgtcgtt aatctgcatc gcgcagaaga
     8941 gcctgactgg gatagctatg atcgcgtagt gattggcgcg tctattcgtt atggtcatta
     9001 ccacagcgcc tttcaggagt ttgttaagaa atatgccacg cggttgaacg gaatgccgag
     9061 cgccttttat tccgttaacc tggtggcgcg taaagctgaa aaacggacgc cgcagactaa
     9121 cagctacgcg cgtaagtttt taatgagttc tccgtggcga cctgactact gtgccgtcat
     9181 tgcaggcgcg cttcgctatc cccgctatcg ctggtatgac cgtctgatga tcaagcttat
     9241 tatgaagatg tcgggcggcg aaacggatac cagtaaagaa gtggtgtaca ccgactggga
     9301 gcaagttgcg cactttgccc gtgaaatagc ccatttaacc aacaaatcgt cggcaaaata
     9361 aacgcaaaga ataaaaagtg c
//
LOCUS       DAJVKX010000153         9371 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.153, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000153 DAJVKX010000000
VERSION     DAJVKX010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9371
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.153"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            32..1321
                     /locus_tag="OPY25_003906"
     CDS             32..1321
                     /locus_tag="OPY25_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate degradation bifunctional
                     isomerase/decarboxylase"
                     /protein_id="HCS0929395.1"
                     /translation="MKGTVFAVALNHRSQLDAWQEAFSQPPYNAPPKTAVWFIKPRNT
                     VIRHGEPIPYPQGEKVLSGATVALIVGKTASRIRPEAAADYIAGYALANEVSLPEESF
                     YRPAIKAKCRDGFCPLGEMAPLSDVDNLTIITEINGREADHWNTADLQRSAAQLLSAL
                     SEFATLNPGDAILLGTPQNRVALRPGDRVRILAKGLPALENPVVAEDEFARHQTFTWP
                     LSATGTLFALGLNYADHASELAFTPPKEPLVFIKAPNTFTEHHQTSVRPNNVEYMHYE
                     AELVVVIGKTARKVSEAEAMEYVAGYTVCNDYAIRDYLENYYRPNLRVKSRDGLTPIG
                     PWIVDKEAVSDPHNLTLRTFVNGELRQEGTTADLIFSIPFLISYLSEFMTLQPGDMIA
                     TGTPKGLSDVVPGDEVVVEVEGVGRLVNRIVSEESAK"
     gene            1318..2783
                     /gene="hpaE"
                     /locus_tag="OPY25_003907"
                     /pseudo
     CDS             1318..2783
                     /gene="hpaE"
                     /locus_tag="OPY25_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460075.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate semialdehyde
                     dehydrogenase"
     gene            2785..3636
                     /gene="hpaD"
                     /locus_tag="OPY25_003908"
     CDS             2785..3636
                     /gene="hpaD"
                     /locus_tag="OPY25_003908"
                     /EC_number="1.13.11.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxyphenylacetate 2,3-dioxygenase"
                     /protein_id="HCS0929396.1"
                     /translation="MGKLALAAKITHVPSMYLSELPGKNHGCRQAAIDGHIEIGKRCR
                     EMGVDTIIVFDTHWLVNSAYHINCADHFQGVYTSNELPHFIRDMTYDYDGNPALGHLI
                     ADEAVKLGVRAKAHNIPSLKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRKL
                     GEAILKAIEKYDGTVAVFASGSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWRE
                     GKFKEFCTMLPEYADYCYGEGNMHDTVMLLGMLGWDKYDGKVEFITDLFASSGTGQVN
                     AVFPLPA"
     gene            3646..4026
                     /locus_tag="OPY25_003909"
     CDS             3646..4026
                     /locus_tag="OPY25_003909"
                     /EC_number="5.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate
                     Delta-isomerase"
                     /protein_id="HCS0929397.1"
                     /translation="MPHFIAECTENIREQADLPSLFSKVNEALAATGIFPIGGIRSRA
                     HWLDTWQMADGKHDYAFVHMTLKIGAGRSLESRQEVGEMLFGLIKAHFADLMENRYLA
                     LSFEIAELHPTLNYKQNNVHALFK"
     gene            4170..4973
                     /gene="hpaH"
                     /locus_tag="OPY25_003910"
     CDS             4170..4973
                     /gene="hpaH"
                     /locus_tag="OPY25_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-hepta-3-ene-1,7-dioic acid hydratase"
                     /protein_id="HCS0929398.1"
                     /translation="MLDKQTHTLIAQRLNQAEKQREQIRAVSLDYPNITIEDAYAVQR
                     EWVNIKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGGDIPTDRFIV
                     PRIEVELAFVLAKPLRGPHCTLFDVYNATDYVIPALELIDARSHNIDPETQRPRKVFD
                     TISDNAANAGVILGGRPIKPDELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWL
                     ANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGAISCRFV"
     gene            4984..5775
                     /gene="hpaI"
                     /locus_tag="OPY25_003911"
     CDS             4984..5775
                     /gene="hpaI"
                     /locus_tag="OPY25_003911"
                     /EC_number="4.1.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxoheptanedioate aldolase"
                     /protein_id="HCS0929399.1"
                     /translation="MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGE
                     HAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEAR
                     NAVAATRYPPAGIRGVGSALARASRWNRIPDYLHQANDAMCVLVQIETREAMSNLASI
                     LDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEAL
                     AKRYLELGALFVAVGVDTTLLARGAEALAARFGAEKKLSGASGVY"
     gene            5847..7223
                     /gene="hpaX"
                     /locus_tag="OPY25_003912"
     CDS             5847..7223
                     /gene="hpaX"
                     /locus_tag="OPY25_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate permease"
                     /protein_id="HCS0929400.1"
                     /translation="MSDTSSALPESPESVGSHNALSTGQQTVINKLFRRLIVFLFVLF
                     IFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFYATYVIFGIPSNVMLSIVGARRW
                     IATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARA
                     NALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDD
                     TPAKAKWLTAEDKKCLQEMMDNDRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTL
                     AYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTVLGMIYWSRHSDKHQ
                     ERKHHTALPFLFAAAGWLLASATDRNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLR
                     ARAIGIAVINATGNIGSALSPVMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMK
                     ASRPRATP"
     gene            7233..8129
                     /gene="hpaA"
                     /locus_tag="OPY25_003913"
     CDS             7233..8129
                     /gene="hpaA"
                     /locus_tag="OPY25_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate catabolism regulatory
                     protein HpaA"
                     /protein_id="HCS0929401.1"
                     /translation="MCQRAIANIDISKEYDESMGSNDVHYQSFARMADFFGRDMQAHR
                     HDQFFQMHFLDTGQIELQLDDHRYSVQAPLFVLTPPSVPHAFITESDSDGHVLTVREE
                     LVWPLLEVLYPGTREAFGLPGICLSLADKLNELAALKHYWQLIERESTEQLAGCEHTL
                     VLLAQAVFTLLLRNAKLDDHAATGMRGELKLFQRFTLLIDNHFHQHWTVPDYACELHI
                     TESRLTDICRRFANRPPKRLIFDRQLREAKRLLLFSDNAVNEIAWQLGFKDPAYFARF
                     FNRLAGCSPSQFRQREVPSFLN"
     gene            8143..9081
                     /locus_tag="OPY25_003914"
     CDS             8143..9081
                     /locus_tag="OPY25_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCS0929402.1"
                     /translation="MMKKSVAMLAVCMLAQSHLAIAAGAPAPQEINIVLLGTKGGPSL
                     LNTARLPQATALTIGDKIWLIDAGYGASLQLVKNGIPLRNINTILLTHLHSDHILDYP
                     SLLMNAWASGLKDHTIQVYGPPGTQAMTKASWKVFDRDITLRMEEEGKPDPRNLVKAT
                     DIGQGVIYKDELVTISALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSWFPPLATFA
                     QGADILVHEAVHVPSVAKLANSIGNGKTLAEAIASHHTTIEDVGKIAREAHVKKLVLS
                     HLVPATVADDVWQQEAMKNYPGPVIVGHDNMTISVP"
BASE COUNT         2122 a         2520 c         2667 g         2062 t
ORIGIN      
        1 agcccgttaa atcggcctga ggagtttatg tatgaagggt actgttttcg ccgttgcgtt
       61 aaaccatcgc agccagcttg atgcctggca agaggctttc tctcagcctc cctataatgc
      121 gccgcctaaa accgcagtgt ggttcatcaa gccgcgtaat acggtgattc gtcacggcga
      181 acccattcct tatccgcagg gagaaaaggt actgagcggc gcgacagtgg cgctcattgt
      241 ggggaaaacc gccagccgga tacgccctga agcggcggcg gactatatcg ccgggtatgc
      301 gctggctaac gaggtcagcc tgccggaaga gagcttttat cgcccggcga ttaaagcgaa
      361 atgtcgcgat ggcttttgcc cgctgggtga aatggcgccg ctgagtgatg tggataatct
      421 caccattatc actgaaatca acggacgaga agcggaccac tggaatactg ccgatttaca
      481 gcgtagcgcc gcacaactgc ttagcgcgtt aagtgagttc gctacactta accctggcga
      541 tgcgatctta cttggtacgc cgcagaatcg cgttgcgctg cgtcccggcg atcgggtgcg
      601 tattctggcg aaaggtttac ccgcgctgga aaatccggtt gtcgcagaag atgaattcgc
      661 ccgccaccag acgtttacgt ggccgctgtc agcgacggga acgttatttg cgctggggtt
      721 gaactacgcc gatcacgcca gcgagctggc atttacgccg ccgaaagagc cgctggtatt
      781 tatcaaagcg ccaaacacct ttaccgaaca tcaccaaacg tcggtgcgcc cgaacaacgt
      841 cgaatatatg cactacgaag ccgagctggt cgtggtgatt ggcaaaacgg cgcgtaaggt
      901 gagcgaagcc gaagccatgg agtatgtggc cggttacacc gtctgtaacg actacgcgat
      961 ccgcgactat ctggaaaact actaccgtcc gaatctgcgg gtaaaaagcc gcgacggcct
     1021 gacgccgata ggcccgtgga ttgtggataa agaggcggtt tctgatccgc acaacctgac
     1081 gttacgcacc tttgtcaacg gtgagctgcg gcaggaaggg acgaccgccg atctgatctt
     1141 cagcatcccg ttcctgattt cttatctgag cgaatttatg acgttgcaac cgggcgacat
     1201 gattgccacc ggtacgccga aagggctgtc cgatgtggtg ccgggggatg aagttgtcgt
     1261 tgaagtagaa ggcgtgggtc gcctggttaa ccgaatcgtc agtgaggaga gcgcaaaatg
     1321 aagaaaataa atcattggat taacggcaaa aacgttgcag gtaacgacta cttccagacc
     1381 actaacccgg cgaccggtga tgtgctggcg gaagtagcct ccggcggtga agcagaagtg
     1441 aaccaggctg tcgcggcggc aaaagaggcg ttcccgaaat gggccaacct gccgatgaaa
     1501 gagcgcgcgc gcctgatgcg ccgccttggc gacctgattg accagcatgt gccggaaatc
     1561 gcggcgatgg aaaccgccga caccggcctg cctattcacc agactaaaac gtgctgatcc
     1621 cgcgcgcctc gcataacttc gaattcttcg ccgaagtgtg ccagcagatg aacggcaaga
     1681 cctatccggt tgacgataaa atgctcaatt atacgctggt gcagcccgtc ggcgtctgcg
     1741 cgctggtgtc gccgtggaac gtgccgttta tgaccgcgac ttggaaagtt gcgccgtgcc
     1801 tggcgctggg taacaccgcg gtgctcaaaa tgtccgagct gtcgccgctg actgccgaca
     1861 ggctgggcga gctggcactg gaggcaggaa ttccggcagg cgtgctgaac gtggtgcagg
     1921 gctacggcgc gacggcgggc gatgcgctgg tacgccacca tgacgtgcgt gcggtgtcgt
     1981 ttaccggcgg taccgccacc ggtcgcaata tcatgaaaaa tgccgggctg aaaaaatact
     2041 cgatggagct gggcggcaaa tcgccggtgc tgatttttga agacgccgac attgagcgcg
     2101 cgctggacgc cgcgctgttc accatcttct cgatcaacgg cgaacgctgc accgctgggt
     2161 cgcgcatctt tatccagcag agcatttacc ctgagttcgt gaagcgcttt gccgaacgcg
     2221 cgaatcgcct gcgtgtcggc gatccgaccg acccgaacac ccaggtcggc gcgctgatta
     2281 gccaacagca ctgggagaaa gtctccggtt atatccgcct cggcattgaa gagggggcaa
     2341 cgctgctggc gggcggtgcg gaaaaaccca ctgacctgcc tgcgcatctg aaaggcggta
     2401 acttcctgcg cccaaccgtg ctggccgatg tcgacaaccg tatgcgcgtt gcgcaggaag
     2461 agatctttgg gccggtcgcc tgcctgctgc cattcaaaga cgaagcggaa gggttacgtt
     2521 tggcgaacga tgtggaatac ggtctggcct cttatatctg gacccaggac gtgagcaaag
     2581 tgttgcgcct ggcgcgtggg attgaagccg gcatggtctt cgtcaacacc cagaacgtcc
     2641 gcgacctgcg ccagccgttc ggcggcgtga aagcctccgg taccgggcgc gaaggcggcg
     2701 aatatagctt cgaagtgttt gcggaaatga aaaacgtctg catctcaatg ggcgaccatc
     2761 ctatcccaaa atggggagtt tgatatgggc aagttagcgt tagcagcaaa aattacccac
     2821 gtgccgtcga tgtatctttc tgaactgcca ggaaaaaatc acggttgtcg tcaggcagcc
     2881 attgatgggc atattgaaat tggcaagcgt tgccgcgaaa tgggcgttga caccattatc
     2941 gtattcgaca cccactggct ggtgaatagc gcttaccaca ttaattgtgc cgaccatttc
     3001 cagggcgtct ataccagcaa cgaattgccg cactttattc gcgacatgac ctatgactat
     3061 gacggtaatc cggcgctcgg ccatctgatc gccgacgagg cggtcaaact gggcgtgcgc
     3121 gccaaagcgc acaacatccc gagcctgaag ctggagtatg gcacgctggt gccgatgcgc
     3181 tacatgaaca gcgacaagca cttcaaagtg gtctccatct cggcgttctg cactgtgcat
     3241 gattttgccg acagccgcaa actgggcgaa gccattctca aggcgattga gaaatatgac
     3301 ggtaccgtag cggtattcgc cagtggttct ctgtcgcacc gttttattga cgaccaacgg
     3361 gcggaagagg ggatgaacag ctacacccgc gagttcgatc atcaaatgga cgagcgcgtg
     3421 gtcaagctgt ggcgcgaagg caaattcaag gagttttgca ccatgttgcc ggagtacgcc
     3481 gactactgct acggcgaagg caacatgcac gacacggtca tgctactggg aatgctgggg
     3541 tgggacaaat acgacggcaa ggtggagttc atcaccgacc tgttcgccag ctccggtacc
     3601 ggccaggtaa acgctgtttt cccgctgcct gcgtaagggg ggtttatgcc gcactttatt
     3661 gctgaatgta ctgaaaatat tcgcgagcag gctgatttac caagcctgtt cagcaaggta
     3721 aacgaggcgc tggccgccac cgggattttc cccatcggcg gtatccgcag tcgcgcccac
     3781 tggctggata cctggcagat ggctgacggt aagcatgatt acgcgtttgt gcatatgacg
     3841 ctgaaaatcg gcgccgggcg cagcctggag agccgtcagg aagtcggcga aatgctgttt
     3901 gggctgatta aagcccactt cgccgacctg atggagaacc gctatctggc gctgtcgttt
     3961 gagattgccg agttacatcc aacgctcaat tacaaacaaa acaacgtaca cgcgttattt
     4021 aaatagcaca ctctttcgcc cggtggcgct gcgctgaccg ggcctacaaa aaaacgatgc
     4081 acgaagcagt accgaaccgt aggccgggta agacgcaccc gcgtcgccac ccggcgcagc
     4141 agcaccgaat gaggtaacag gaagcaacta tgctcgataa acagacccat accctgatcg
     4201 ctcagcgact taatcaggct gaaaaacagc gtgaacagat tcgcgcagtg tcgctggatt
     4261 atcccaacat cactattgaa gatgcctatg ccgtacagcg tgaatgggtc aatatcaaga
     4321 ttgccgaagg gcgcacgctc aaaggccaca aaatcggcct gacctcaaaa gcgatgcagg
     4381 ccagctcgca aatcagcgaa ccggattacg gcgcgctgct tgacgatatg ttcttccatg
     4441 acggcggaga tatccccacc gaccgtttta tcgtcccgcg tattgaagtg gagctggcgt
     4501 tcgtgctggc gaaaccgctg cgcggccctc actgcacgct gttcgacgtc tacaacgcca
     4561 cggattatgt gattccggcg ctggaactga ttgacgcccg cagccacaac atcgacccgg
     4621 aaacccagcg cccgcgcaaa gtgttcgaca ccatttccga caacgccgcc aacgccgggg
     4681 tgatcctcgg tggtcgcccc atcaaaccag acgagctgga tctgcgctgg atctccgcgc
     4741 tgctctatcg caacggcgtg atcgaagaaa ccggcgtcgc cgcaggcgtg ctgaatcatc
     4801 cggccaacgg cgtggcgtgg ctggcgaaca agcttgcccc ctacgatgtc cagcttgaag
     4861 ccgggcagat catcctcggc ggctcgttca cccgcccggt gccggcgcgc aagggcgaca
     4921 ccttccatgt cgattacggc aacatgggcg cgatcagttg ccggtttgtg taaggaaaaa
     4981 acgatgaaaa atgctttcaa agacgcgtta aaagcggggc gcccgcaaat cggtttgtgg
     5041 ctggggcttg ccaacagtta cagcgctgaa ctgttagcgg gcgccggctt cgactggcta
     5101 ctgattgacg gtgaacacgc gccaaacaac gtgcagacgg tgttgaccca gttgcaggcg
     5161 attgcgcctt atcccagcca gccggtggtg cgtccgtcat ggaacgatcc ggtacagatt
     5221 aagcaactgc tcgacgtcgg cgcgcaaacg ctgctgatac cgatggtgca gaatgccgat
     5281 gaagcgcgaa acgccgtggc ggctacgcgt tatccgcctg ccggtattcg cggcgtgggc
     5341 agcgcgctgg cgcgggcatc gcgctggaat cgcattccgg actatctcca ccaggccaac
     5401 gacgccatgt gcgtactggt gcagattgaa acgcgtgagg cgatgagcaa tctggcgtca
     5461 attctcgacg tggatggcat tgacggcgtg tttattggcc cggcggatct cagcgccgat
     5521 atgggctttg ccggcaatcc gcagcacccg gaagtgcagg cggcgattga gaacgccatc
     5581 gtgcagatac gcgcggcggg gaaagcgccg gggattctga tggccaatga agcactggcg
     5641 aaacgttatc tggaactggg ggcgctattt gtcgccgtcg gcgttgacac cacgctgctg
     5701 gcgcgcggag cggaggcgct ggcggcgcgc tttggcgcag aaaaaaaact gtccggtgcg
     5761 tccggcgtct attaagcctg ggccggtaag cgcagcgcta ccgggcaacc gtagtaccct
     5821 acaaaattcc catcagagga aaaaaaatga gcgacacatc atctgcactt ccggaaagcc
     5881 ccgagtctgt cggttcgcac aacgcgctca gcacgggtca acaaaccgtc ataaataaac
     5941 tgttccgccg actgatcgta tttttattcg tgttgtttat cttctcgttt ttagaccgta
     6001 tcaacatcgg ttttgccggg ttgacgatgg ggcaggatct ggggttaagc gccaccatgt
     6061 ttggtcttgc cacgacgctg ttttacgcca cctacgtcat tttcggcatt cccagcaacg
     6121 tgatgttgag catcgtcggc gcccgccgct ggattgcgac cattatggtg ctatggggca
     6181 ttgcatctac cgccacgatg ttcgcggtgg gaccgaaaag cctgtatgtg ctgcgaatgc
     6241 tggtgggcat taccgaagcg ggctttttgc caggaatatt gctctattta acctactggt
     6301 tcccggcatt tttccgcgcc cgcgccaacg cattatttat gattgccatg ccggccacta
     6361 ccgcgttggg gtcaattgtc tccggctata ttttatcgct ggacggcata ttcaatctgc
     6421 atggatggca gtggttattc ctgttggaag gatttccgtc agttttgtta ggcattatgg
     6481 tctggtttta cctggatgat accccggcaa aagccaaatg gctgacggca gaggataaaa
     6541 aatgtttgca ggagatgatg gataatgatc gcctgacgct ggttcagcct gagggggcca
     6601 tcagccataa cgccatgcag cagcgtagcc tgtggcgcga agtattcacg ccaattgtac
     6661 tgatgtatac gctggcctat ttttgcctta ccaatacgct tagcgccatt agtatctgga
     6721 cgccgcaaat cctgaaaagt tttaatgaag gcagcagcaa tatcaccatc ggcctgctgg
     6781 cggcgatccc gcagatttgt actgttctgg gcatgattta ctggagccgc cattcggaca
     6841 aacatcagga gcgtaaacac cacactgcgt taccgttcct gtttgccgcc gcgggctggc
     6901 tgctggcgtc ggcgaccgac cgtaacctga tccagctcct ggggatcgtg atggcatcca
     6961 cgggttcctt tagcgcgatg gcgatcttct ggaccacgcc ggatcagtcg atcagtttac
     7021 gcgccagggc gataggcatt gcggtcatca atgccaccgg caatattggc tccgcgctca
     7081 gcccggttat gattggctgg ctaaaagata tcactggtag cttcaatagc ggactctggt
     7141 ttgtcgcttc tctgttagtc gtcggcgccg ccattatctg gctcattccc atgaaagcat
     7201 cgcgtccgcg cgccacccct tgaggagaaa ctatgtgcca acgtgcgatc gccaatattg
     7261 atatcagcaa agagtatgac gaaagcatgg gcagtaacga tgtgcattat cagtcgtttg
     7321 ctcgtatggc ggatttcttt ggtcgtgata tgcaggcgca tcgccacgac cagttttttc
     7381 aaatgcactt tcttgatacc gggcagattg agctacagct cgacgatcat cgctattcgg
     7441 tgcaggcgcc gctatttgtg ctaacgccgc cctcggtgcc gcatgctttt attaccgaat
     7501 cggatagcga tggtcatgtt ctgacggtac gcgaagagct ggtttggccg ctgctggaag
     7561 tgctttatcc cggcaccaga gaggccttcg gcctgccggg aatctgcctg tcgctggcgg
     7621 ataaactcaa cgagctggcg gcgctcaaac attactggca gctaattgag cgggagtcca
     7681 cggaacaact ggctggctgc gaacatacct tggtactact ggcgcaggcg gtatttacct
     7741 tgctgttgcg taatgcgaag ctggacgatc atgccgcaac cgggatgcgc ggtgaactga
     7801 aactttttca gcgctttacc ctgttaattg acaaccactt ccatcagcac tggacggtgc
     7861 ccgattatgc ctgtgagttg catattaccg aatctcgttt gaccgatatt tgccgacgtt
     7921 ttgctaatcg cccgcctaaa cgcctgattt ttgatcggca attacgcgag gcgaaacgac
     7981 tgctgctttt ttccgacaat gctgtcaacg agatcgcctg gcaattaggt tttaaagatc
     8041 cggcttattt cgcccgtttc tttaatcgcc ttgctggctg ttctccttcg cagtttcgcc
     8101 aacgtgaagt tccttctttt ctcaactaag aagagtaaaa acatgatgaa aaaaagcgtc
     8161 gctatgctgg cggtttgtat gctggcgcaa agccaccttg ccattgctgc cggtgctcct
     8221 gcgcctcaag agatcaacat tgttttactg ggcaccaaag gcgggccttc tttgctcaat
     8281 acagccagac taccgcaagc gacggcgctc actatcggcg ataagatatg gctgatagat
     8341 gccggctacg gcgccagtct gcaactggtg aaaaatggca ttccactgcg caacatcaat
     8401 actattttgc tcacccatct gcacagcgac cacatactgg attatccttc cttgctgatg
     8461 aatgcctggg caagtggcct gaaagaccat accatacagg tttatggccc gccgggaacc
     8521 caggcgatga cgaaggctag ctggaaggtc tttgacaggg atatcacgtt acgcatggaa
     8581 gaagagggga aacccgatcc gcgcaacctg gttaaggcga ccgatatcgg ccagggcgtc
     8641 atctataaag atgaactggt cacaataagc gcgctgaaag tgcctcattc ccctttcccg
     8701 gacggtgaag cgtttgctta ccgttttgat actcagggta agcgaatcgt cttctctggc
     8761 gatacgtcct ggtttcctcc gcttgcaacg tttgcccagg gggcggatat cctggtacat
     8821 gaggcggtac atgtcccttc ggtagcaaaa ctggctaata gtattggcaa cggaaaaacg
     8881 ctggctgaag cgattgcgtc gcatcacacc acgattgaag atgtcggtaa gattgctcgc
     8941 gaggcccacg tgaaaaaact ggtgttaagt catctggtgc ctgcgacggt tgcggatgac
     9001 gtctggcaac aggaagccat gaaaaattac ccgggccctg tcattgtcgg tcatgacaat
     9061 atgacgataa gcgtaccgta agcatcaggg caggggtaaa ccaacgggct gacatcatgt
     9121 cagcccgtta tgcttttggc gatcagcatg acgcgcagag cttttgtcta aaacattatt
     9181 ttttctaaac actacttgct gatttttatg cacaataaag gtaagatgat tgctctggtg
     9241 aaatatcact aaataagaat gtcacggatg gaatttatac agtgttaaaa gcaatgcgtt
     9301 tctttgtctg ccggccatca gtaatatcct ctgtaccggc tcctcgttgc caaagtgaag
     9361 gttagattaa a
//
LOCUS       DAJVKX010000154         9282 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.154, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000154 DAJVKX010000000
VERSION     DAJVKX010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9282
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.154"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(59..547)
                     /locus_tag="OPY25_003915"
     CDS             complement(59..547)
                     /locus_tag="OPY25_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCS0929403.1"
                     /translation="MSENKNVQDTHISEQMKALHGALIRVVSALNRPRNDEKLIAEAG
                     IQLDRALFSILISIERLGPIGVVELAERAGRDYTTVSRQVAKLEKLGLIIRQHNVIDR
                     RIREAVISRTGKAMTERIDAAREQMGNVVFKDWPQDKIDIFVRLMQKFADAMDSDASM
                     PE"
     gene            592..1754
                     /locus_tag="OPY25_003916"
                     /pseudo
     CDS             592..1754
                     /locus_tag="OPY25_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent monooxygenase"
     gene            1744..2985
                     /locus_tag="OPY25_003917"
     CDS             1744..2985
                     /locus_tag="OPY25_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929404.1"
                     /translation="MNTNVYENTDSETITPLNKRRILPVFLLVGLYAASTAAVMSVLP
                     FYIREMGGSPLIIGIIIATEAFSQFCAAPLIGHLSDRVGRKRILIVTLAIAAISLLLL
                     ANAQCILFILLARTLFGISAGNLSAAAAYIADCTHVRNRRQAIGILTGCIGLGGIVGA
                     GVSGWLSRISLGAPIYAAFILVLGAALVAIWGLKDPSTTSRTTDKIASFSARAILKMP
                     VLRVLIIVMLCHFFAYGMYSSQLPVFLSDTFIWNGLPFGPKALSYLLMADGVINIFVQ
                     LFLLGWVSQYFSERKLIILIFALLCTGFLTAGIATTIPVLIFAIVCISIADALAKPTY
                     LAALSVHVSPARQGIVIGTAQALIAIADFISPVLGGFVLGYALYGVWIGIAISVAIIG
                     LVTAMIYLSKSSPLIAKPETE"
     gene            3055..4611
                     /locus_tag="OPY25_003918"
     CDS             3055..4611
                     /locus_tag="OPY25_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoPQ-activated pathogenicity-related family
                     protein"
                     /protein_id="HCS0929405.1"
                     /translation="MFKRYLWKLCWLAFALVKRGESMKKIYLVVIVLFFISTKVYTLL
                     HNNIFFCRNSPECDLSHVLPDYREQISGTPLKYTLISTAPLAQVVVRHYELLSQHWSP
                     DDMVTPAQWRHNVDIYIPETAKEHHALVVVNNGINYEKGIQIPSKPVDFTQQTLASIA
                     RDTNTIVISVSDIPNQYLTFQDDKKPLKEDESVSRSWALFMEAPEQRELMPLNIPMVT
                     AISQAMRLAKKELTQWNINSFIITGISKRGWTTWLSAIADPDVEAIVPFAIDLLDIDA
                     SLEHIYQSYGGNWPITFYPYYQQGIDEKIKSPTFTQLRQIIDPLRYLNTIYQPRLAIP
                     KYIINASGDDFFVPDNTRFYYSKLPGVKSLRIVPNMNHYSINQFAEGSLVPFINRFQS
                     KKTLPQLIGLIHHHLLTVYFSEAPVKVVRWTANNPNARDFRYACGIRYQPLTIDIPAN
                     NKISITLNEPKTGWEATYIEATFNDGYVATSQVYITPDEKYPQTAPPSVNAACQTLPG
                     RGLGENDSPD"
     gene            4788..6074
                     /locus_tag="OPY25_003919"
     CDS             4788..6074
                     /locus_tag="OPY25_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929406.1"
                     /translation="MKRKTMGWLIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAA
                     EMGMIFSAFFIGYALFNFIDGWASDKVGPKTVFLIAALLWSVFCGLTGLVTGLWTMLI
                     VRVLFGMAEGPVSAAGNKIINNWISRKESATAIGIFSAGSPLGGAVSGPIVGLLALSL
                     GWRPAFGIIFLFGLVWVLLWYFIVSDKPTMSKRLAPEERIDFENHEDVILSDDGRATP
                     SLGYYMKQPMVWATTLAFFSYNYILFFFLTWFPSYLNHSLHLDIKEISIATVIPWVIG
                     AIGMVLGGVCSDVIYRITGNALLSRRLILGVCLAGAAVCVAVSGTVSTIGSAITLMSV
                     SLFLLYLTGPIYWAVIQDVVHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYD
                     YAFYLAGAIAIVSSLLVFVFVKSKGFKANESQSCVH"
     gene            6049..7074
                     /locus_tag="OPY25_003920"
     CDS             6049..7074
                     /locus_tag="OPY25_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCS0929407.1"
                     /translation="MKVKAVFINKPGEVETRWVDYPHKKENEVLIKVDAAGICGSDIG
                     AFRGTNPLVTYPRIIGHEVTGIVLQEGTGMPDNIKKGDRVIVDPYIYCGHCYPCSVGR
                     TNCCENLNVIGVHIDGAMQEVVTHPAHLIHKIPDNVPSEMAPLAEPLTIALHALHRAN
                     VKAGEYVAIIGAGAIGLMAALSARHYKATPILIDIVEERLRYAQKLGVPYVLNAADDQ
                     VIDAIKNITHGTMAQVVIEASGANSAIRNTLDLASFAGRISFTGWPKQETSLPTNLIT
                     YKELDLRGSRTSAGEFDEALRMLSTLEINPQDVVSKVVNLDEIPDAVKELDRYPERYL
                     KINAVFH"
     gene            complement(7133..7924)
                     /locus_tag="OPY25_003921"
     CDS             complement(7133..7924)
                     /locus_tag="OPY25_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCS0929408.1"
                     /translation="METTGGCFSLSCTVINYHDHQRQDGMLNPFKIPWIWIGGRMVIP
                     EVRQERLYQKIANLIIKLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEISG
                     WIVIQSGNGVIVSDKKHLASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIY
                     HRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQS
                     GDRNVLLNLNKQHKAIVDAMRQSDADSAYEGSLEHLRYVRKIVGG"
     gene            complement(7970..9061)
                     /locus_tag="OPY25_003922"
     CDS             complement(7970..9061)
                     /locus_tag="OPY25_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCS0929409.1"
                     /translation="MMKKSKAMLFIAPALFSYAMAAQACTTLAIQDKQGDIFHGRTLE
                     YMQDLPSWLTYYPAGTQFDKKTPDGSQGISYQAKYPILAITSTITDGDSRDILEGMNS
                     AGLSFSENMIMNAQLPPLPASEYKQAIPVTSLGEWALARFATVGEVKQAIKEGKFWSP
                     ELHRFGDLKSPFHYAFYDKKGGSIVVEVENGKFHVYDNPTRVMTNGPAFPWHLTNLNN
                     YTQLTNVDRSSGTLGGIKVMQPDSGIAIADLPSSDTSVSRFIRGVYYTTYAPQATSAH
                     DAMNTLAHIMSRFDRPKNITVDYMGSEGEGNATRKPVSEYTVWTTLSDLTHGEMMVRG
                     YNDINYKTWSLSQFKNATAPVFEKINVKG"
BASE COUNT         2362 a         2218 c         2109 g         2593 t
ORIGIN      
        1 ggctatttaa ttaatgcagt agcatggacg atcagatttg accgcccttt tcttttgctt
       61 attccggcat tgaagcatcg ctatccattg catcggcaaa cttttgcatt aaccgaacaa
      121 agatatcaat tttatcctga ggccagtctt taaaaacaac gttgcccatt tgctctcgcg
      181 cagcgtctat acgctccgtc atcgcctttc ctgtccggga gataacggcc tcgcgtatac
      241 gacgatcgat gacattatgt tgccgtatta tcaatcccaa cttctccagt ttggcgacct
      301 gtcggcttac cgtcgtataa tcacgaccgg cacgttcggc taactcaaca acgccaatcg
      361 gccctaaacg ttcgatacta ataaggatcg aaaatagcgc gcgatcgagt tgaatccccg
      421 cctctgcaat taatttctca tcattacgag gccggttgag cgcgctcacc acgcgaatca
      481 acgcaccgtg aagtgccttc atttgctcgg aaatatgtgt atcttgcaca tttttatttt
      541 ctgacatagc atgtctcctc ttatgtgcat aatacacata ttggagagac gatgacaaca
      601 tacaccacta cagatgtact gatctgcggc gctggcgtta ccgggcttac tttagccatc
      661 gaactggcgc gtcacggggt ctcatttcgc ctgattgaga aaagagcgac gccttttacc
      721 ggttcccgcg gtaaaggtat tcagccgcga acgcaagaaa tcttcgagga tattgggata
      781 ctcaataaag tggtcgccgc cggcgggctc tatccccgat tacgaaccta ccgtcatgac
      841 ggaagctacg tagattcaga tattgcgcat aatacaaaac cgacccacgc cgaaccctac
      901 catctgccat tgatggttcc acagaacgtg acagaaacga ttatgcggga gcaattaaaa
      961 gcatggggac atcgggtgga gttcggctgc gagttacgac attttgcgca aaccccacgc
     1021 acggtcaccg cgtatgttgc cgggccaact ggagaagagg tcatcatcgc gcattatttg
     1081 ataggcgcgg atggcggcgg aagctttgtc agaaagaaat taggcgtcag cttccccggc
     1141 cgtacgttgg gaatccatgc gcttgtggct gacgcttcac ttaccaggga tggaaaatgg
     1201 cagcctcgct acggggcgca ggagaagagc ttctcgatag ctatgaacag gaacgccgcc
     1261 cggtagccga atcactgctc cacctttcta cccgattact tgactctcaa aaacagggtg
     1321 gcatcaaacg agaacgcgac gttcaacaac ttgacatcca gtataccaac tcccccttag
     1381 cccacacgtt gcccgaacgt cagcatgggt tacaagcggg agaaagagct ccggatgctc
     1441 ctcttttggg cgccggcggc caatcattac gattatttca gttactccag ggtccggact
     1501 ggaatctgtt ggcctacgaa acccacggta aggtcatcga tgcgcggcga ggtctgcgta
     1561 ttcatcacat tggcgagcag gacgagctca tcgataccct ggggcacttc cgggagtcct
     1621 atcatctggc cccgggtcaa tgcgtgctga tccgacccga tggctatgtc ggcgcattct
     1681 ttcacggcaa acagagcaac gatattgaaa attatctctc tcgttttgcc atagggatta
     1741 aagatgaata ctaatgtcta tgagaacacc gacagcgaaa ctatcacccc gctcaacaag
     1801 cggcgtattt tgcctgtttt cctgcttgtc ggcctttacg ccgccagtac agcggctgtg
     1861 atgtcggtac tgccttttta tatccgcgag atgggcggtt cgccgcttat cattggaatc
     1921 atcatcgcca ctgaggcttt tagccaattt tgtgcagcgc ccctgattgg ccacctttcc
     1981 gatcgcgttg gccgcaagcg aatactgatt gtcacgctgg ctattgcggc gataagttta
     2041 ctattactcg ccaacgcgca atgtatcctg tttatcctgc tcgcccgcac gctttttggc
     2101 attagcgccg ggaatttgtc agccgccgca gcctatattg ccgattgtac gcacgtcaga
     2161 aatcggcgcc aggcaatcgg tatcctcaca ggctgcattg gtttaggcgg tattgtcggg
     2221 gcaggcgttt ccgggtggct atcgcgtatc agtctgggtg cgccgatcta cgccgccttt
     2281 atacttgtcc ttggggctgc cctggtcgcg atttgggggt taaaagaccc ttccacaaca
     2341 tcacgtacca cagataaaat agcgtcgttc tctgcccgcg ctattttaaa gatgccagtc
     2401 cttcgcgtct taatcatcgt aatgctttgt catttcttcg cctatggcat gtactcttca
     2461 caattacctg tttttctttc tgacaccttc atctggaatg ggcttccctt tgggccaaaa
     2521 gcgttaagct atctgttaat ggcggacggg gttattaata ttttcgttca gctatttctg
     2581 ttaggttggg tgagccaata tttttcggag cgaaagctaa ttatcctcat cttcgccctt
     2641 ctttgtactg gatttctcac tgcgggtatc gccacgacca taccagtgct tatttttgct
     2701 atcgtttgta ttagcatcgc tgatgcgcta gccaaaccca cttatcttgc cgccttgtcc
     2761 gtccatgtat cgcctgcccg acaaggtatc gtcatcggaa cggcgcaggc attaatcgca
     2821 atcgctgatt ttatatcccc cgtattgggc ggatttgtcc tgggttatgc cctgtatggc
     2881 gtctggatcg gtatagctat ctctgtcgcc attattggtc tggtgacggc aatgatttac
     2941 ctttcaaaaa gttcaccgct aatagcgaaa ccagaaacag aataatgtga caacgtcaca
     3001 agcattatta ctcccttctt cccttattta tcaaaagtat tgtacttata ttgaatgttt
     3061 aagaggtatt tatggaaatt atgctggttg gcatttgccc ttgtaaagcg cggggaaagc
     3121 atgaaaaaaa tatatctcgt tgttatcgta ctgtttttta tttctacaaa agtttataca
     3181 ctacttcata acaacatctt cttttgtcga aacagcccgg agtgtgattt gtctcatgtt
     3241 ctccccgact accgggagca gatttcaggc acaccgctaa aatatacctt aattagtaca
     3301 gctccattag cacaggtggt agtcagacac tatgaattat tatcgcaaca ctggtcgcca
     3361 gatgacatgg taacccctgc gcaatggcga cataacgttg atatttatat ccctgaaacg
     3421 gcaaaagagc accatgcttt ggtggttgta aacaacggaa ttaattatga aaaaggcata
     3481 caaatcccca gtaaacccgt tgattttact cagcaaacac tggcaagcat cgcccgtgat
     3541 acgaatacca tcgtaatatc agtgagtgat atacctaacc aatatttaac ctttcaggat
     3601 gataaaaaac cactgaaaga ggacgagagc gtttcccgaa gctgggcatt atttatggaa
     3661 gcgccggagc aacgtgagtt aatgccttta aatattccta tggtcactgc catatcgcaa
     3721 gcgatgagat tagcaaaaaa ggagttaacg caatggaata taaattcctt tatcattaca
     3781 ggtatttcaa agcgtgggtg gaccacctgg ttgtcagcta ttgccgatcc tgatgttgaa
     3841 gcaattgttc ccttcgccat tgatctactt gatattgatg cttcacttga gcatatttat
     3901 caatcatacg gtggaaattg gcccattaca ttctacccct actaccagca aggcatagat
     3961 gagaaaataa aatcccccac atttacccag ctaaggcaaa taatagatcc gttaagatat
     4021 ctcaatacta tttaccaacc ccgccttgca ataccgaaat atattattaa tgcaagtggc
     4081 gatgatttct tcgtaccaga caatactcgc ttttattata gcaaacttcc tggcgtaaaa
     4141 tcattacgta tagtgcctaa tatgaaccac tactcaatta accagttcgc tgaaggaagc
     4201 ctcgttccat ttattaaccg gtttcaaagt aaaaaaacat taccgcagtt gatcggcctt
     4261 attcaccacc atcttcttac ggtctatttc tcagaagcgc cggtaaaagt cgttcgctgg
     4321 acagccaaca atccaaatgc gcgtgatttc cgttatgcct gtggcatccg ctatcagccg
     4381 cttacaatag atattcccgc caacaataag atcagtatta cgttaaatga accgaagaca
     4441 ggttgggaag ctacctatat cgaagccact tttaatgatg gctatgtcgc cacgagtcag
     4501 gtttatatta cgcccgatga aaaataccca cagacagcac caccttccgt taacgccgca
     4561 tgtcaaacgt taccggggcg tggattaggg gaaaacgata gccccgattg aattttcaag
     4621 taattgtctg attttaaata attttatcca tcacgcttgc gatggataaa aatcctctgc
     4681 gataaatttt tgttatattg atcacgttct aaccacaaga taggtgattt gaaaataacc
     4741 ttaaaatatt gtggtcaggc cgctagacca caataagagg attaatcatg aaaagaaaaa
     4801 caatgggatg gcttatcgtt tttcttctat ttatagttta catgctcaac tatatggatc
     4861 gttcagcatt gtcgataact gcccccttga tcgaaaagga gttaggattt aacgccgcgg
     4921 agatgggaat gatcttcagc gcatttttta tcggatacgc cctgtttaat tttattgatg
     4981 gctgggccag cgataaagtt gggccaaaaa cggtttttct catcgcagcg ttactatggt
     5041 ctgtattttg tggcttaact ggtttagtca ccggattgtg gacaatgctt atcgtgcgcg
     5101 ttcttttcgg tatggctgaa ggaccggtca gcgctgccgg aaataaaatc atcaataact
     5161 ggatttcccg aaaggagtct gccacggcga tcggaatttt tagcgccggt tccccgctcg
     5221 gcggcgcggt gtccgggccg attgtgggcc tgttggcgtt atccttaggc tggcgccccg
     5281 catttggcat tattttctta tttggcttgg tctgggtact actgtggtac tttatcgtta
     5341 gcgataagcc aacaatgagt aaacgcctgg cgccggaaga acgcattgat tttgaaaatc
     5401 atgaggacgt tattttatct gatgatggcc gggctacgcc ttcactcggc tattacatga
     5461 aacaaccaat ggtatgggcg acaactctgg cttttttcag ctacaactat attctttttt
     5521 tcttcctgac ctggttccca agttatctga accattcgtt acatctcgat attaaagaaa
     5581 ttagtatcgc cacggtaatt ccctgggtca tcggcgccat tggtatggtg ctcggcggcg
     5641 tctgttctga tgtaatttat cggattaccg gtaatgccct gctctcacgt cgacttattc
     5701 tgggcgtatg tctggcaggc gcggcggtat gtgttgccgt ttccggtacc gttagcacta
     5761 ttggtagcgc aattacgctc atgtcagttt cactcttcct gctctattta acaggcccaa
     5821 tttattgggc ggttattcag gatgttgttc ataaagataa ggtagggagc gtcggcggag
     5881 ccatgcatgg cctggctaat atatccggta ttatcggtcc gcttgtcacc ggttttatcg
     5941 ttcaatttag cggtaaatat gactatgcgt tctatctggc tggtgctatc gctatcgttt
     6001 caagcctgtt ggtcttcgtg tttgtaaaaa gtaaaggatt caaagccaat gaaagtcaaa
     6061 gctgtgttca ttaataagcc tggtgaagtt gaaacccgct gggtggatta tccccataag
     6121 aaagaaaatg aagtattaat taaggttgat gccgcaggca tttgcggatc ggatatcggg
     6181 gcttttcgtg gaacgaaccc acttgttact tacccaagaa ttattgggca tgaagtgacc
     6241 ggaattgttc ttcaggaagg caccggaatg ccggacaata ttaaaaaagg cgaccgcgtg
     6301 attgttgacc cctatattta ttgtggtcac tgctaccctt gctctgtcgg cagaactaat
     6361 tgttgtgaaa atttaaatgt cattggcgtg catatcgatg gcgcaatgca ggaggtggtt
     6421 actcatcccg cacatttaat tcataaaata ccagataatg tgccttctga aatggcgccg
     6481 ctggcagaac cgctgaccat cgctctacac gcgctgcatc gggcaaacgt taaggccggg
     6541 gaatatgttg ccatcatcgg cgcgggggcc attggtctta tggcggcatt aagcgcgcgt
     6601 cattacaagg caacgcctat tctgatcgat attgtggaag aaaggctacg ctatgcgcaa
     6661 aagcttggcg ttccttatgt actgaacgcc gctgacgatc aggttatcga cgctattaaa
     6721 aatatcaccc acggcaccat ggcgcaggtc gtgatagaag cctccggcgc aaatagcgct
     6781 attcgaaata cgcttgattt agcatcgttt gctggtcgta tttcgtttac cggatggcca
     6841 aaacaggaaa cgtcgctgcc gacgaacctg atcacctaca aagaactgga tttacgcggc
     6901 tcccgcacca gtgccggtga atttgatgag gcattacgca tgctgtcaac gctggagatt
     6961 aatccgcaag atgttgtcag taaggtcgtc aatcttgatg agatccctga tgcagttaaa
     7021 gaacttgatc gctatccgga gcgttactta aagattaatg ctgttttcca ttgatttacg
     7081 gcgagttcta ccgcatggca tatccgccat gcggtgttat ttaccgacaa acttagccgc
     7141 cgacaatctt tctcacatag cgtaaatgtt ccagcgatcc ctcataagcg ctgtcagcat
     7201 cagactggcg catcgcatcc actatcgctt tatgttgttt gttgagatta agtaaaacat
     7261 ttctgtctcc agactgttca tcaagcccgg cgtaagggat attaatccgt tgttcccata
     7321 acatacggga catatcaaac aacacccggt tacggctggc ctcagagatc gcaaggtgaa
     7381 actctttatc cagcgagtaa aagccgtgga cgttattatc gttaatggct tgatccatac
     7441 gatgataaat cgcctctatt tggttgatga cgtcaacgtt atcgttttgt gcggctaagc
     7501 gcgcacaatg gctatcgacc agctcgcgag tagagagaat ttcttcgatg gtatagtcac
     7561 tggcaaggtg ttttttatct gaaacgataa ccccattacc ggactgaatc acgatccatc
     7621 cggagatctc cagtacaata agggcttctc gcaaggaggc gcggctcacg ccaagctgtt
     7681 ttgccagttc gcgttctggc ggtaaaaaag ttcccggtgg aaaaatatta tcattgatca
     7741 gcttaatgat gaggttggct atcttctgat agagcctctc ctgcctgacc tcaggtataa
     7801 ccatgcgccc tccaatccat atccagggga ttttgaatgg atttagcata ccatcctggc
     7861 gctggtgatc gtgataatta attaccgtgc atgataaaga gaagcaaccg ccggtagtct
     7921 ccattacctt cgccgagact accggggaaa ctaaacagag acgagcggtt tatcctttga
     7981 cgttgatttt ctcgaacacg ggcgcagtcg cgttcttaaa ctgagaaagg gaccaggttt
     8041 tatagttgat atcattgtag ccgcgcacca tcatctcacc gtgcgtcaag tcagacagcg
     8101 ttgtccagac cgtatattct gagaccggtt tgcgggtggc gttgccttcc ccttcactcc
     8161 ccatataatc aaccgtaata tttttcggac gatcaaaacg gctcataata tgtgcaagcg
     8221 tattcattgc gtcgtgggcg gatgtcgctt gcggcgcata tgtggtgtaa taaacgccgc
     8281 gtataaaacg ggaaaccgac gtatcggacg atggcaagtc tgcaatagca atcccgctat
     8341 caggctgcat cacttttatc ccgcccaatg tgcctgaaga gcggtccaca ttggttaatt
     8401 gcgtataatt attcagattt gtcagatgcc aggggaatgc gggaccattt gtcatcacgc
     8461 gagtgggatt gtcatagaca tggaatttgc cattttccac ttcaacgaca atgcttcctc
     8521 ctttcttgtc gtaaaacgcg taatgaaatg gcgatttcag atcgccaaac cgatgcagtt
     8581 ccggtgacca gaatttgccc tcttttattg cctgttttac ctcgccgaca gtagcaaaac
     8641 gggccagcgc ccattctccc aacgaggtga caggaattgc ctgtttatat tcactcgcgg
     8701 gcaatggcgg caactgcgca ttcatgatca tgttttcact aaatgacaat cccgcgctat
     8761 tcatgccttc aagtatgtct ctgctatcgc catcagtaat ggtggaagta atggccagta
     8821 tcggatactt cgcctgatag cttatcccct ggctgccatc cggcgttttt ttatcaaact
     8881 gcgttcccgc cggataatac gttaaccatg agggtaaatc ctgcatatat tccagcgtac
     8941 gcccatgaaa aatatcgcct tgtttatcct gaatagcaag ggttgtgcag gcctgtgcag
     9001 ccatggcgta tgaaaacagc gccggagcga taaataacat tgctttactt tttttcatca
     9061 tgctctcctt gtttgtaaaa tggattggat gaatatatta aattaaacct atcaatggtt
     9121 atgcagcacg taattaattg tgatcttatt ttacaagcta ataaatttaa ctgacgggtt
     9181 taaaggagag ttaaacacag cgaactaaca tgaaacgcgt tatccgtgtg accatttaaa
     9241 aaaatcccat catgttataa ataaaaaaca cggtttctta tc
//
LOCUS       DAJVKX010000155         9258 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.155, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000155 DAJVKX010000000
VERSION     DAJVKX010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9258
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.155"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            125..811
                     /gene="istB"
                     /locus_tag="OPY25_003923"
                     /pseudo
     CDS             125..811
                     /gene="istB"
                     /locus_tag="OPY25_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
     gene            complement(876..1037)
                     /locus_tag="OPY25_003924"
                     /pseudo
     CDS             complement(876..1037)
                     /locus_tag="OPY25_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365374.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1124..1237)
                     /locus_tag="OPY25_003925"
     CDS             complement(1124..1237)
                     /locus_tag="OPY25_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0929410.1"
                     /translation="MMPTDGNDNTRKQDGAVFGQPEVKPMPETLQCTEKWR"
     gene            complement(1357..2304)
                     /locus_tag="OPY25_003926"
     CDS             complement(1357..2304)
                     /locus_tag="OPY25_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0929411.1"
                     /translation="MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLS
                     RLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITSSFQSLLDELRNPDKIIRGSIKF
                     SAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESED
                     LVYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQEESY
                     TISGAVNVHLSSNNLLSVLNLVLEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDL
                     PIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD"
     gene            complement(2796..3036)
                     /locus_tag="OPY25_003927"
                     /pseudo
     CDS             complement(2796..3036)
                     /locus_tag="OPY25_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309415.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
     gene            complement(3119..3940)
                     /locus_tag="OPY25_003928"
     CDS             complement(3119..3940)
                     /locus_tag="OPY25_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCS0929412.1"
                     /translation="MSYARHLPVLMYHHVSDKPGQITLSPRTFRAQMKWLAESGWKTV
                     TAAAVEAFYHGARLPRKSVMLTFDGGWLDNWLQVFPVLQEFNLHAHLFLVTSLISDGP
                     VRIPAGEPVYSHDECQMLVKQGRVDEVMLRWSEVREMHLSGLVEFHSHTHTHRRWDQK
                     PVSRNPSDLLRVDILLSRKRMREMLGYCSQHLCWPEGWYCSDYIHVAEELGFTYLYTT
                     ERRMNNPVIGSQRIGRINTKERKNVGWLKRRLFYHTTPGFSSLLARHKGARRIAD"
     gene            complement(4348..4818)
                     /locus_tag="OPY25_003929"
     CDS             complement(4348..4818)
                     /locus_tag="OPY25_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin structural protein SafD"
                     /protein_id="HCS0929413.1"
                     /translation="MWMKIQRVKTVIYSVSLLVAASSLVPIANAAEKLQTTLRVGTYF
                     RAGHVPDGMVLAQGWVTYHGSHSGFRVWSDEQKAGNTPTVLLLSGQQDPRHHIQVRLE
                     GEGWQPDTVSGRGAILRTAADNASFSVVVDGNQEVPADTWTLDFKACALAQEDT"
     gene            complement(4840..7350)
                     /locus_tag="OPY25_003930"
     CDS             complement(4840..7350)
                     /locus_tag="OPY25_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HCS0929414.1"
                     /translation="MKFKQPALLLFIAGVVHCANAHTYTFDASMLGDAAKGVDMSLFN
                     QGVQQPGTYRVDVMVNGKRVDTRDVVFKLEKDGQGTPFLASCLTVSQLSRYGVKTEDY
                     PQLWKAAKTPDECADLTAIPQAKAVLDINNQQLQLSIPQLALRPEFKGIAPEDLWDDG
                     IPAFLMNYSARTTQTDYKMDMVGRDNSSWVQLQPGINIGAWRVRNATSWQRSSQLSGK
                     WQAAYTYAERGLYSLKSRLTLGQKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPV
                     VRGIARTQARVEVKQNGYTIYNTTVAPGPFALRDLSVTDSSGDLHVTVWEADGSTQMF
                     VVPYQTPAIALHQGYLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQS
                     ATHYQAASLGLGGSLGRWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNL
                     FLTRWQYASQGYNTLSDVLDSYRHNGNRLWSWRENLQPSSRTTLMLSQSWGRHLGNLS
                     LIGSRTDWRNRPGHDDSYGLSWGTSIGGGSLSLNWNQNRTLWRNGGHRKENITSLWFS
                     MPLSRWTGNNVSASWQMTSPSHGGQTQQVGVNGEAFSQQLDWEVRQSYRADAPPGGGN
                     NSALHLAWNGAYGLLGGDYSYSRAMRQMGVNIAGGIVIHHHGVTLGQPLQGSVALVEA
                     PGASGVPVGPWPGVKTDFRGDTTVGNLSVYQENTVSLDPSQLPDDAEVTQTDVRVVPT
                     EGAVVEAKFHTRIGARALMTLKREDGSAIPFGAQVIVNGQDGSADLVDTDSQVYLTGL
                     ADKGELTVKWGAQQCRVNYHLPAHKGIAGLYQMSGLCR"
     gene            complement(7374..8114)
                     /gene="papD"
                     /locus_tag="OPY25_003931"
     CDS             complement(7374..8114)
                     /gene="papD"
                     /locus_tag="OPY25_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pili assembly chaperone PapD"
                     /protein_id="HCS0929415.1"
                     /translation="MKIISFGVMAAVLFVSNSITPPVYAAEQKLSLNTKSFSVKLGAT
                     RVIYHAGTVGATLSVSNPQNYPILVQSSVKAADKSSPAPFLVMPPLFRLEANQQSQLR
                     IVRTGGDMPTDRETLQWVCVKAVPPENEPSDTQAKGATLDLNLSINVCDKLIFRPDAV
                     KGTPEDVAGNLRWVEAGNKLKVENPTPFYMNLASVTVGGKPITGLEYIPPFADKTLNM
                     PGSAHGDVEWRVITDFGGESHPFHYVLK"
     gene            complement(8189..8687)
                     /locus_tag="OPY25_003932"
                     /pseudo
     CDS             complement(8189..8687)
                     /locus_tag="OPY25_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789648.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Saf-pilin pilus formation protein SafA"
     gene            complement(8820..>9258)
                     /locus_tag="OPY25_003933"
     CDS             complement(8820..>9258)
                     /locus_tag="OPY25_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929416.1"
                     /translation="CYAGSIVVGSEQQSSVDIGFASPQQLSVTFAPVAGLKAGVIKSN
                     TEIATIAVSSVAAKQFAIAADFKAKNVMNGDTWTLYGKNTGKGIKVYFYGETTSPKGN
                     VNYNGHQWIIYDINDKLGVKLAGDQNVPADVFPMTVNIAAYQA"
BASE COUNT         2451 a         2491 c         1992 g         2324 t
ORIGIN      
        1 attgatgcca gtcccttacc tgtcaatgtt gtttacggtt cctttccccc ttttgtgcga
       61 gtaagcaaca tgaatataca agtcttaacg accaatgcct ctgtcagccc aaaataagtc
      121 gacattcctg tgcatggcgc tgcagcagga atagaacggc agacatcagc gcggaatgga
      181 atcccggctg aaacaggctc gtctgccatg agtcaaaacg ctggagcagt tcgacttcag
      241 cttccagcca ggcatcgatc gtaaggtcgt ccgggagttg gccggtctgg cgttcgtgga
      301 gcgctgcgag aatgtgatcc tgctggggcc cccggagtgg agaaaaccca cctggccgct
      361 gcccccggtg tgaaagcggc agatgtgggc catcgggtgt tgttcatgcc gcaggacagg
      421 ttggtagacg ctgatgaaag cgaagctgga aaaccgcctg gagcgccagc tacaacaact
      481 gagctatgcg cgggggctga tcctggacga aataggttac ctgccaatga ccagtgagga
      541 agccagtctg ttcttccgac tgctgaaccg acggtatgaa aaagcgagca ttatcctgac
      601 gtcaaacaaa ggcttcgcag actggggaga gatgttcggt gataacgtgc tggcaacagc
      661 gatcctggat cggctactgc atcactcaac cacactgaat atcaaaggag aaagttacca
      721 actgaaggaa aaacgcaaag tcggggcgct gaccaaaagc gcaacgccaa tcagtgaaga
      781 tgaaatggcg gaaagcggac agcagaagtg atcaaacagc ggatattaaa aatagcgaaa
      841 aacgaccata aatcctggcg ttgacatcct caagatttaa tatcagaagc ttccatgccg
      901 ccgtatccag acttccagtt gtccctggtg gcttcagaaa taccggcctc ccggtagaca
      961 tctttaacag tccgtccgga ttcaactgat ctaatcacag cgatgatctg gtgcgcagta
     1021 atacgggctt tacgcacagc gatctcctgc gttggcagat tgattatgcc ggatgatctc
     1081 taaatgtgaa tggctcgatt atgcgggata cttacagtgc aacctagcgc catttttcag
     1141 tacactgcaa cgtttctggc atgggcttaa cttccggctg cccaaaaaca gccccgtcct
     1201 gtttccgggt attatcattt ccgtcagtcg gcatcatgtt ttgtattggg catcgtcaaa
     1261 agacgactgg ccggccagtc gcatatctcg atgcctcaat tcagtcatca tcatgtgggt
     1321 ttaagtcagg aacgtgtcaa aaccattcca aacgagttaa tcatcattca gaaaatcaat
     1381 ttgtgggcga ttattccatt tatcttcaat aaaagacaga aagcgttgaa ataaaggaga
     1441 ataatactga cgatgacgcc atacaagata aatggggaga tctggaactc tccattcagg
     1501 aagtataatt tcaagttcat tattttttaa gtatttagtg gcaagccagg ccggagtcat
     1561 gaggttgata cccttccctt ctaaaaccaa attaagaaca ctcaaaagat tattggaaga
     1621 taaatgaaca ttaacagcgc cactaatagt gtatgattcc tcttgacgga aaagagtaag
     1681 aggtccggaa agaccatggt tgtgaagacc cacaataatg tgattttcca aatcgccagg
     1741 atgtgagatc ctgccatatt ttctgatata tttcggactt gcacaaagaa ccaactttaa
     1801 agggcttatc tttcgataca cgagatcctc actttcgatt atgccacttt taaaaaccag
     1861 ctcatcaaac tccagggatt tactaaaaaa atcgctacgc tctcgtgaat ccaggtagat
     1921 ttttgtatcc ggatagctag ctgtaaattc ccatatccac ttattggcaa gaaactcaca
     1981 gacaatagcc ggagccgaaa attttatact ccctctgata attttatccg gatttcgcaa
     2041 ttcatccagc aaggactgaa aggaagatgt tatccttttc atgcttgcat aggctgtctg
     2101 accagctcca gtcagctcta agtgatgtga atcgcgccga agtaaagtaa cctcaataga
     2161 attctcaagg cgactaagcg atttactgac agcagaaatg ctaatatcta attcccgcgc
     2221 agcccgggaa agattcccta cttccgccac tttaataaat atcatccaat ctcgcatacc
     2281 acgattattg atcagttcca tcattatctt ccgttgataa aagaaattct tatattaaag
     2341 gagctatcaa cgacttactg atgcgtcatt gtgtgcctca atgtccttga tatcatcata
     2401 ataaaaaacc tattggctgc aaaatagcat ctgaatcgat catgattttg catccatctc
     2461 cggttactaa ttgaacctgt ttaccactca gtgtaaatac cctatctcag aagcgatcgt
     2521 caaggttgtc gccgaaccag atctcaataa taaagtggtt cattgtcatg cgcccgttct
     2581 gcaaaggcat tctccttttc tgtgacgcag tctggagcgc attaattgta tcgttcacct
     2641 aacaaagtat cccgtggaaa caagcaaaac atcgccagat tattcttact tgagtccccc
     2701 acccggctcg acattatttg tgaaagcgga ggaaacagaa cagacggttt aaataagacg
     2761 cttactcaaa acataaacct atgtgcaggc tcctctcatt tcgtcacgtc gctgatatcc
     2821 agctttactg gtgccagggg aagatatctg cgcaaggcaa taattccggc gcaacaacaa
     2881 ccactcccgc tgggcctctg tacattcaaa atcgcccatg accaaaagcc agcgggtaga
     2941 agccctgcgc cagtgacctg ctgcctccag attctgcgca accgggtcta tcacggcttc
     3001 cggtgttatc ttatttctgc tcaaaatcag caccatcatt tgggatatag cctacaaccc
     3061 ctgcccgccg atgatggggg aggattcggt atgcagcact ttcatcctgg tctccggctc
     3121 agtcagctat ccgacgtgcc cccttatgcc gggccagcag cgaagaaaat ccgggcgtgg
     3181 tgtgataaaa caggcgacgt ttcagccagc ccacattctt tcgctccttt gtgttgatac
     3241 gaccaatacg ctgtgaaccg atgactggat tgttcatacg cctttctgtg gtatacaggt
     3301 atgtgaaccc cagctcttca gccacatgaa tataatcaga acaataccag ccctcaggcc
     3361 agcacagatg ctgactgcag taacccagca tctccctcat ccgcttacga ctaagaagaa
     3421 tatcgacacg aagcaaatcc gacggattac gggacacagg cttctggtcc cagcgtcggt
     3481 gggtgtgcgt gtgcgaatga aactcaacaa ggccactgag gtgcatctcc cggacctctg
     3541 accagcgcag catgacctca tcaacccggc cttgtttaac cagcatctga cactcatcat
     3601 gagagtacac cggttcgcct gcaggaatac gaaccggtcc gtcactgatc aaactggtca
     3661 caagaaagag atgcgcatgc agattaaact cctgcagcac cggaaaaacc tgcaaccagt
     3721 tatccagcca gccgccatca aaagtcagca tgacgctttt acgaggcaat cttgcaccat
     3781 gataaaaagc ttccaccgct gcagcagtaa cggttttcca gccagattca gccagccatt
     3841 tcatctgcgc ccggaacgta cggggagata aggttatctg tccgggttta tcactgacat
     3901 ggtgatacat taataccggt aaatgtcgtg cataagacat atgctttatt cctttatgta
     3961 aaaaataaat tatttttacg cctgagggga caagaaaaag ccccctaaac ataaaatctt
     4021 aaatatcaca tatgaatacc tgacagataa acaaacctta tactaagggc ttataaagcc
     4081 ccgctcacaa aagagtgaat caaacaaatc cacaaaacag aaaataataa aggcatcagt
     4141 gtccgttaaa ttattttacg aaacataata ttcctctccc tacaaaaaaa gatgaatttc
     4201 agattttaaa atcaatcagc aattgatttt tctgcaatga agattgctaa ccatatttgc
     4261 cttgagtaaa ttttcaatac atcctcgaac ctgatataca gtattcgcct tattcactga
     4321 tacaggaagt atgagtggaa cagacggcta cgtatcctcc tgcgccaatg cacaggcctt
     4381 aaaatccagc gtccaggtgt ccgcaggcac ttcctgattg ccatcaacga ccacactgaa
     4441 actggcgtta tctgcagcgg ttcttaaaat ggcgccacga ccactcaccg tatctggttg
     4501 ccacccctcg ccctccaggc gaacctgaat gtgatggcga ggatcctgtt gcccgctcag
     4561 cagcaatacg gtaggcgtgt tacccgcctt ttgctcatcg ctccataccc gaaacccgct
     4621 gtgactgccg tgataagtca cccagccttg cgcaagcacc atcccatctg gcacatgccc
     4681 ggcccgaaag taagtaccta cacgtagcgt tgtctgaagt ttttctgcgg cgttcgctat
     4741 cggcaccaag ctactggcag cgaccagtaa gcttacgcta tagataaccg ttttcactcg
     4801 ctgtattttc atccacatta ttctctcctt cagaatcggc tatctgcaga gaccgctcat
     4861 ttgatacaag cccgcgattc ccttgtgggc aggtaggtgg tagttaaccc gacattgctg
     4921 tgctccccat ttcaccgtca gttcgccctt atccgccaga ccagtgagat aaacctggct
     4981 atcagtatcc accagatcag cgctgccatc ctgcccattg actataacct gcgccccgaa
     5041 aggaatggcg ctaccatctt cccgtttcag cgtcatcagt gccctggccc cgatgcgagt
     5101 gtgaaacttc gcttccacca ccgccccttc ggttggcacc acgcgcacat cggtttgtgt
     5161 gacctctgcg tcatccggta gttgcgacgg atcgaggctg actgtattct cctgatagac
     5221 gctcaggttg cccactgtgg tgtcgccacg aaaatccgtc ttaacgccag gccaggggcc
     5281 aactggcacc cccgaggccc ctggcgcttc aaccagcgcc actgagcctt gcaaaggttg
     5341 ccccagcgtc acaccatgat ggtggataac tatacctccc gcgatattga ctcccatctg
     5401 gcgcatcgcc cggctgtagc tatagtcacc acctaacagg ccgtaagccc cattccatgc
     5461 caagtgcaat gcgctgttat taccaccacc tggcggggca tcggcacggt aactctgacg
     5521 cacctcccaa tccagttgct gactgaatgc ctctccgttg acccccactt gttgcgtctg
     5581 accaccgtgt gatggtgaag tcatctgcca actagcactt acattattcc ccgtccagcg
     5641 gcttaatggc atactgaacc acaggctggt tatgttctct ttacggtgcc cgccattgcg
     5701 ccacagcgtt ctgttttgat tccagttcaa tgacagcgag ccccctccga tagaggttcc
     5761 ccaactcagt ccgtagctgt catcatgacc ggggcgatta cgccagtcgg tacgggaacc
     5821 gattaaactc agattgccca aatgcctccc ccatgactga ctcaacatca gggtggtacg
     5881 tgagctcggc tgcaaatttt cccgccacga ccatagacgg ttgccattat gtcgataact
     5941 gtcgagcaca tcggataggg tgttatagcc ctgcgaggca tattgccatc tcgtcagaaa
     6001 caaatttgtc cccgtcgcag tcagctggtt gctgtaacgc agtcgccagg aggctccttg
     6061 ctgtaccgct tccccctgac gctgactgtg tgtgtcgctt ccatcgacag ataaactccc
     6121 ccaccgcccg agagatcctc ccaaaccaag cgatgcagct tgatagtgcg ttgcactctg
     6181 tataccgcca tatgcagtga gattccacgg cagaccatac atcaacgtag cctgcgcgat
     6241 ctgcgcctta tccgttgcag agtctgacga tcggtatcgg cccgccaaca ggctgtactt
     6301 caaatatccc tggtgcagtg ctatcgccgg ggtctgatac ggcaccacaa acatttgtgt
     6361 actgccatcg gcctcccaca cggtgacatg cagatcacca ctactgtctg ttaccgacag
     6421 atcccgcagt gcaaacggtc cgggcgccac ggtggtgttg taaatggtgt aaccattctg
     6481 tttgacctcc acccgagcct gcgtgcgggc aatcccacgc actaccggag caaactgccg
     6541 ctcactgtag ggcaccatgt tgtcatccga tgccaacatc acaccggtaa atggcacact
     6601 atcaaatatc tccccctgcg aagtcttttg ccccagagtc agacgacttt ttagtgagta
     6661 cagtccacgc tcagcatagg tatatgctgc ctgccacttc cccgacagtt gactactccg
     6721 ctgccagctg gtcgcattgc ggacacgcca cgcacctata ttgattcccg gttgcagttg
     6781 tacccaggaa gagttgtcac gccccaccat atccattttg taatccgtct gcgttgtcct
     6841 cgcactgtag ttcatcagaa acgccggaat accatcatcc caaagatctt ctggagcgat
     6901 ccccttaaat tccggacgca acgccaactg cggaatactc agttgcagtt gctgattatt
     6961 gatatccagt accgctttag cctgtggaat ggcggtcaga tccgcacact catctggggt
     7021 ctttgctgct ttccacaact gagggtaatc ttccgttttt acgccgtagc gtgaaagctg
     7081 actgaccgtc aaacaagaag ccagaaaagg cgttccttgc ccatcctttt ctaatttgaa
     7141 caccacatca cgggtgtcga cacgtttacc attcaccatt acgtccactc gataagtccc
     7201 tggctgttgt accccctggt taaagagcga catatcaacc cctttcgctg catcgcccaa
     7261 cattgatgca tcgaatgtgt aagtgtgcgc atttgcgcag tgaaccactc ccgcgataaa
     7321 cagtagcaag gcaggttgtt tgaacttcat attctgccgc taagcccctg gatttattta
     7381 aggacgtagt ggaacggatg actttcacca ccaaagtcag taataactct ccactcgaca
     7441 tcaccatggg cactacctgg catatttagt gttttgtcag caaaaggggg gatatactca
     7501 agccctgtaa tgggctttcc ccctactgtg acggaggcta aattcatgta aaacggggtg
     7561 gggttctcca ccttaagttt gttgcccgcc tccacccatc ttaaatttcc tgcaacatct
     7621 tccggcgtcc ccttcacggc atccgggcgg aaaatcagct tatcacagac gttgatggac
     7681 aaattgaggt caagggtcgc gcccttagcc tgtgtatccg acggttcatt ttcgggtggt
     7741 accgccttta cacagaccca ctgtaaagtc tcacgatccg ttggcatgtc accaccagta
     7801 cggacaatac gcagttgact ctgctggttc gcttctaaac gaaatagagg cggcatcacc
     7861 aaaaaaggag caggcgaact tttgtctgct gctttgactg aagactgaac caaaataggg
     7921 taattctgcg ggttgctcac cgagagcgtg gctccaactg taccagcgtg ataaatcacc
     7981 cgtgtagccc ccagcttcac gctgaatgat ttagtgttta aacttaattt ctgctcagcg
     8041 gcatacactg gaggagttat agaattagag acgaataaaa cagccgccat tacaccaaaa
     8101 ctaataattt tcatattaca agttataaaa aaatgtatga cttgatattt attgcgcttt
     8161 aataaagcgc aataaaagtt gtttactatt aagcttgata ctccgctatg tgtatcgtca
     8221 ctggataagt atcagccttt accgtttgtg atccagacaa tttcacagcg actttgtctg
     8281 tcatgttata tatccaccac ttatgcgaag caccatccac taatgaacct tttgagccac
     8341 aggctacccc cccaaaggta attttaatgg tattaccact tttaccaatt accgtccaca
     8401 catcgctgtc gttgcccact gttttcaggt ttagaataat ctcccgttac cacgtattgt
     8461 ttgctcgaac cgcttgccga aagtatagca atagcctcat cacccttatg aggccctgcc
     8521 accaagccag acactggagt aagctgtgct tgtagttgtc caggattgct gaagtttaca
     8581 tccgccgaca cgccagtgct tgtattcggc acgagcgagc cagcataaca actagcagcc
     8641 ataatgctca atgcgcttgc gataattaaa tcttttatgt ttttcatcgg aaatccacct
     8701 tttcaaaatc ccccagcaca tcaagaatga ataatgtcat accaaaattc accgtacaga
     8761 aaagcctgtg gctgggaata ctttaagact taataatact taatagaagt tgcttactat
     8821 taagcttgat atgccgctat gtttacagtc attgggaaga catcagctgg gacattctga
     8881 tctccagcta gtttaacacc aagtttgtcg ttaatatcat atatgatcca ctgatgccca
     8941 ttgtaattta cattcccctt tggtgaggtt gtctcaccat agaagtacac tttgattcct
     9001 ttgccagtat ttttaccata taaagtccat gtatcgccat tcatgacatt ctttgcctta
     9061 aaatccgctg cgatcgcgaa ttgtttagca gcaacagaac taactgcaat agtcgcaatc
     9121 tccgtattag acttaatcac cccagccttt aagcccgcca ctggagcaaa tgttacgctc
     9181 aactgctggg gagaggcaaa gccaatatcc actgaacttt gttgctctga gcccaccacg
     9241 attgaaccag cataacaa
//
LOCUS       DAJVKX010000156         9223 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.156, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000156 DAJVKX010000000
VERSION     DAJVKX010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9223
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.156"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..842
                     /locus_tag="OPY25_003934"
     CDS             <1..842
                     /locus_tag="OPY25_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCS0929417.1"
                     /translation="GSIECLQSAQNWQRKSLSLQGLNLLQSVLIKLTTGKISITTSSG
                     EYITASGPMLIFLAKDQTIHITMEETHEQLNYNLIELDSASIKNAYNFFLYEHADFSA
                     PLTKPTTKHLLAPIETGVARVFNLLHSSNKSQKLSQDKKEYLIRFLLSEFIYEPEAFA
                     LFRELSQNTLAENIYNIIISDISRKWALKDISDSLYMSCSTLKRKLKQEHTSFSEVYL
                     NARMNKATKLLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTPSEFLAFLSSSRHQ
                     YVN"
     gene            839..1126
                     /locus_tag="OPY25_003935"
     CDS             839..1126
                     /locus_tag="OPY25_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463179.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore gernimation protein GerE"
                     /protein_id="HCS0929418.1"
                     /translation="MRYLTMQYKNKAKHINIRDGILLLAKKFDLTLSEKKVIYYVAAG
                     LSVKSCSNLLDRNIKTISTQKRSAYKKMDITTDVELIHLMLNEFYISVDIT"
     gene            1203..1717
                     /locus_tag="OPY25_003936"
                     /pseudo
     CDS             1203..1717
                     /locus_tag="OPY25_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370525.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2004..2909)
                     /locus_tag="OPY25_003937"
     CDS             complement(2004..2909)
                     /locus_tag="OPY25_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HCS0929419.1"
                     /translation="MRYDISRDAICYGFFMRLLKRVIVVVLLGVILFMVRDDIRYVYQ
                     LILKYGDKPSALALSSYKAVIQQKPVAGVKSNLSGLTYSAEDRMLFAVINNPPELVWL
                     TTEGQLVGRMPLQGIHDPESIAWSGGNQFQIGSEKDGAVYKTQVDIQRGAMQIISMVK
                     LEGYDKAKNKGLEGTAWDAKNERLYAAKERKPIMIKEVEMSKNGITRALPSAITASVS
                     DVSGLEYHAPTDSLLVLSDESKMILEVSSEWRVRDRLFLTAEWSGLRDDIPQPEGIAM
                     DNENNLYIVSEPNLFYKFSCDIQND"
     gene            3213..4613
                     /locus_tag="OPY25_003938"
     CDS             3213..4613
                     /locus_tag="OPY25_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1996 domain-containing protein"
                     /protein_id="HCS0929420.1"
                     /translation="MKLNLITVSLATLVAAGAFPAHAGPQAHVVCGYHHTLGDDAIMM
                     FGKANQAMWHDFFGNTHTDAVSTYQTLRAQPDTTCDNKADSSGYWAPSMKLPDGEIVN
                     PAYQKTYYQSTNVAQYPLHPFPAGLELLAGDHHGTGPSSAITFLCANGKGYTNKVGEI
                     CGLRKAGDAVQFNIGIAFPNCWDDVNLKPTHSHNNAIYADHGKCSADYPVKIPTVNMN
                     IAWVLPQISSLDTSKVELSMDPVMHGETREERWGSIYTAHADFMNGWTEDGAQFMTDL
                     CMNQGLDCGTAVPYAYSKAEENTWVSSEDDKPHASVDTLYVQDDWTNGGRTQHPETLT
                     LVKFKIPPLPANMDASLFKYRIRLFGGKTETNGADQIFFYPTSSDWHASSVSWNNKPA
                     INYRSDAVLYLNHSHEYRMVDVDKAVRKALAEGKTEISWYIGGDRQGNHYDFMPADSK
                     QSLVLMLTGFKKTPEL"
     gene            complement(4697..5350)
                     /locus_tag="OPY25_003939"
     CDS             complement(4697..5350)
                     /locus_tag="OPY25_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCS0929421.1"
                     /translation="MPCKPDKRSVIRRNISGAIAMPSRAVLPRILGALFYYSPERPEV
                     KALFDCLPTLPELYPWRDRGHIESLCASWSLPDDDALTWQFSVLFEGQGKMPVPPWGS
                     VYLEKDNLLMGETTADYRAFLQSQGMVFTDREREPEDQFGLMLLACSDLLAQGDNVAA
                     NRLLEAHLLPWGFRYLELLQRNTVSAFYARLAIVATCYLQDVQQQQGLQPEKKRLFF"
     gene            complement(5365..6138)
                     /locus_tag="OPY25_003940"
     CDS             complement(5365..6138)
                     /locus_tag="OPY25_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCS0929422.1"
                     /translation="MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSV
                     MCLFGIGVVVGTFHVGQPLRALNMLLRVGHSPMSNEIVLSAAFVALGGLGALGLLLNR
                     ATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
                     FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAVLLAAGVVGV
                     VVCARLKSSATVLAMTAVVVIAAELAGRIAFYNLWTLPM"
     gene            complement(6131..6757)
                     /gene="dmsB"
                     /locus_tag="OPY25_003941"
                     /pseudo
     CDS             complement(6131..6757)
                     /gene="dmsB"
                     /locus_tag="OPY25_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463171.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
     gene            complement(6771..9205)
                     /locus_tag="OPY25_003942"
                     /pseudo
     CDS             complement(6771..9205)
                     /locus_tag="OPY25_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004391916.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
BASE COUNT         2425 a         2442 c         2165 g         2191 t
ORIGIN      
        1 tggggagcat tgaatgttta caatcagcgc aaaactggca gaggaaatcc ttatcacttc
       61 agggattaaa tttactgcag tccgtactca tcaagctcac cacgggtaaa atttcaatta
      121 cgacatcgtc cggggagtat attacggcat cagggccaat gttaatattt ttagctaaag
      181 atcaaaccat tcatatcact atggaagaga ctcatgaaca gttaaattat aatttaattg
      241 aattagattc agcgtcaata aaaaatgctt ataatttttt tctgtatgaa catgcagact
      301 tttcggcccc attaacaaaa ccgacgacaa aacatctgtt agcgccaata gaaacaggcg
      361 tagcaagagt attcaacctc ttacactctt caaataaaag ccagaaatta tcccaagata
      421 aaaaggaata tttaataaga tttctgcttt cagagttcat ctatgaacct gaagcatttg
      481 ctctcttcag agaactatcg caaaatacat tagccgaaaa catctataat attattataa
      541 gcgacataag tcgaaaatgg gcgctcaagg atatttctga ctcactctat atgagttgtt
      601 ccacattaaa aaggaaattg aaacaagagc acacctcatt cagtgaagtt taccttaatg
      661 cgcgaatgaa taaagcgaca aaacttctac gcaatagtga atataatatt actcgagtgg
      721 cttatatgtg tggttatgat agtgcttctt attttacatg cgtttttaaa aaacatttca
      781 aaactacacc atcggaattt ttagcgtttt tatcctcctc tcgtcatcaa tatgttaatt
      841 gagatatctg acaatgcagt ataagaacaa agcaaaacat attaatataa gagatggaat
      901 tctgttgctc gctaaaaaat tcgatctaac attgagcgag aaaaaagtta tttattacgt
      961 ggctgcagga ttatctgtta aaagttgctc aaatttatta gatcgaaata taaaaacgat
     1021 ttcaacacaa aagagatcag cctataaaaa aatggatatt actactgatg ttgaattaat
     1081 ccatttgatg ctgaatgagt tttacatatc agtcgatatt acgtaatttt ttctaaaatg
     1141 ttgctagaat ggtaggcaag gcaactctgg atatcatctt cagagatcgt tccgcaaacg
     1201 ctatggataa ttcttcgctg tctatcggct ggctgacgat agactctaca ccgccagtac
     1261 gttccatgaa gaataatagt gatattggcg ccggaggcga taatatcact aacatcaata
     1321 caccgacctt ttattgggtc gcttagaagc tcacgcaaca attaagctga ctattgatac
     1381 acaaccgtcc gccgaaccaa cgttgggatc gactgttagc agtctggata ataccgtcag
     1441 ccttaaggga gtcgtggagg cgcatcagga tattcaggtg aaggtcacgg tcgacgatac
     1501 ggactacacc gccagtgtcg ataacgatac cggtaactgg catgtttctg ttccgcaatc
     1561 cgctattctg tcgggggaga atcagtatac cataacggcc accgatcccg ccggtaatag
     1621 cgccgccgcc agtgtaacat ttacaggtac atcgcccacg gaaaatccgg tcaacaagag
     1681 ttccggcgta gatgaaatga ttatgcctga taactaaaca tcaccatgcg aggtctcttc
     1741 ggaggcctcc tgaaaaaaca gaataatatt cattgtctgt taattattac agagagagtt
     1801 aatttataaa aaaaagcggc agactacgct gccgcaaata tgaggaggac aattaccgtt
     1861 acgctacacc acaaagtaat ccgttactga ggtaagtaaa acataaatat ccccaacaat
     1921 gaatcaacaa atcaagcaat cgtcaaatca tggtattaac aaccttgttc tgttttagca
     1981 tgctgtgaca gtaaaaatag attttagtca ttctgtatat cacacgaaaa tttataaaac
     2041 agatttggtt cactcacaat atacaaatta ttttcattat ccatggcaat cccttctggt
     2101 tggggtatat cgtctctgag ccctgaccac tccgccgtca ggaacaatcg atcgcgcacc
     2161 cgccactcgg aactgacctc cagaatcatt tttgactcgt ccgacaacac cagcagcgaa
     2221 tccgttgggg catggtattc aagtccggag acatcgctca cactcgcagt gatggcagaa
     2281 ggcaacgctc tggtgatacc atttttgctc atctctactt ctttgatcat aatgggtttt
     2341 ctttcttttg cggcatataa tctctcattt ttcgcatccc atgccgtacc ttccagccct
     2401 ttattttttg ctttgtcata gccctcaagc ttcaccatgg agattatctg catagcgccg
     2461 cgctgaatat ccacctgtgt tttatagacc gcgccatctt tctcactgcc tatctggaac
     2521 tggttgcccc cactccatgc aatagactcc gggtcgtgga tgccctgcag cggcatccgc
     2581 cctaccagct gcccttctgt cgttaaccag accagttcag ggggattatt aataacggcg
     2641 aaaagcatcc tgtcttcggc ggagtaggtc aaacctgaaa ggttactctt aactcctgcg
     2701 actggttttt gctgaataac cgctttatag ctactcagtg ctagcgccga gggtttatca
     2761 ccatatttga ggatcagttg ataaacatag cgtatatcgt ccctgaccat aaataaaatc
     2821 acgcccaaga gtacaaccac aataacgcgt tttagtaatc tcataaaaaa tccatagcag
     2881 atcgcgtcac gactgatgtc gtaacgcatt tcttaaaaat aaagccgatg tccgatagaa
     2941 tcgttattcg gttatggcga gcgccattag cataggcaaa atgaaatagt gagggttatc
     3001 acaaaaagcc cgattttaat cactaacgta ccctttttgt aaattgacat aatcaagagg
     3061 agggtagttt cggctaatta tttaaatagt acgtctgcaa attcgcccct gtatgcaggg
     3121 caaatgacaa aaagtgataa ttaatgagat gtaacaccgt aatttgatct gctattgctg
     3181 ctcccacttc tattcaaccg ggcagcaaaa aaatgaaact caaccttatt accgtcagcc
     3241 tggctacgct cgttgccgct ggcgcattcc cggcccatgc cggtcctcag gcgcatgtcg
     3301 tgtgcggcta tcaccacacg ctgggcgatg acgcgattat gatgtttggt aaagcgaatc
     3361 aggcgatgtg gcatgacttt tttggcaaca cccacaccga cgcggtctct acctaccaga
     3421 cgttgcgcgc gcaacccgat accacctgtg ataataaagc cgacagctcc ggttactggg
     3481 caccgtccat gaaattaccc gatggtgaaa tcgtaaatcc ggcctaccaa aagacctatt
     3541 atcaatccac aaatgtagcg caatatccgc tccatccatt cccggccggg ctggagttac
     3601 tggcaggcga tcatcacggt actggcccca gttccgcaat caccttttta tgtgccaacg
     3661 gcaaaggtta caccaacaag gtaggcgaaa tatgcggcct gcgtaaagcg ggcgatgccg
     3721 tccagtttaa tatcgggatc gctttcccca actgttggga tgacgtcaac ctgaaaccga
     3781 cacatagcca caataatgct atctatgccg accacgggaa atgttccgca gactatccgg
     3841 ttaaaatccc gacggttaat atgaacatcg cctgggtact cccgcagatc tcctcgctgg
     3901 atacgtccaa agtggaattg tcgatggacc cggtaatgca tggcgaaacc cgggaagagc
     3961 gctggggaag tatttatacc gcccatgccg attttatgaa tggctggacg gaagatggcg
     4021 cgcagtttat gacggatctg tgtatgaatc agggactgga ttgcggcact gcggttcctt
     4081 acgcctacag taaagcggaa gaaaatacct gggtaagcag cgaagacgac aagcctcatg
     4141 ccagcgtcga tacgttgtac gtacaggatg actggacaaa tggcggacgc acgcagcacc
     4201 cggaaacgct cacgctggtg aaatttaaga tcccgcccct gcctgccaat atggacgctt
     4261 cgctattcaa ataccgtatt cgcctttttg gcggcaaaac ggaaacgaac ggcgccgatc
     4321 aaattttctt ttacccgacc agcagtgact ggcacgccag tagcgtgtca tggaacaata
     4381 aaccggcgat caattaccgt tccgatgccg tattatatct aaaccattca catgagtatc
     4441 gcatggttga tgtcgataaa gcggtgcgca aagcgctagc ggaagggaaa acggaaatat
     4501 cctggtatat cggcggcgac cgtcagggaa atcactacga tttcatgcca gcggactcaa
     4561 aacagagcct ggtgctgatg ctgaccggtt tcaaaaagac gccggagctg taatagtaaa
     4621 ctgtgcccgc tgacgcaaca gcgggcacga tggcgacaca agcattacgg cacgtcgtca
     4681 aaacctgacc aataccttag aaaaacaacc gtttcttctc aggttgtagc ccctgttgct
     4741 gctgaacatc ctgcagataa caggtcgcta cgatggcaag ccgggcatag aaggcgctaa
     4801 cggtattgcg ttgcagcaat tccagatagc ggaatcccca gggtagcaga tgcgcctcca
     4861 gtaaccggtt ggccgccacg ttgtcgcctt gcgccagcag atcgctacag gctaatagca
     4921 tcaggccaaa ctgatcttcc ggctcgcgtt cacggtcagt gaataccatt ccctgcgact
     4981 gtaaaaaagc tcgataatcg gcggtggttt cccccatcag caaattatct ttttccagat
     5041 agaccgatcc ccagggcggg acgggcatct ttccctggcc ttcaaacaat acggaaaatt
     5101 gccatgtaag cgcatcatca tccggtagcg accatgacgc gcacagtgat tcaatatgtc
     5161 cgcgatcgcg ccaggggtaa agctcaggca acgttggcaa acaatcgaac aacgctttca
     5221 cctccggcct ctcaggggag tagtaaaaca gtgcgccgag gatacgcggc aaaacagcac
     5281 gggaaggcat agcaatagct cctgaaatat ttcgcctgat gacgctacgc ttatcaggct
     5341 tacatggcac aagccgggca aaaactacat tggcagcgtc cacagattgt aaaacgcaat
     5401 cctacccgcc aactccgccg cgataaccac cacagccgtc atggccagca ccgtagcact
     5461 cgatttcagg cgcgcgcaga ccaccacccc gaccacgccc gccgccagca ataccgcctg
     5521 ggcggtaaac cagctatgct gcgcggcggt cagagcgcta tcggcgctca tcagcgtcgc
     5581 catatagccc gggcgcagac aaaagctcac caaaatcgct aacacgctga ccagtagccc
     5641 cagacggcgc acgccaaaca atgccgccaa cgcgccgccg ccaatcaacg gcgtcaatat
     5701 catcattgcc gtggtgtaag atgaacgcca ggtcgccacc gtcggcagtt ggtaaatctg
     5761 cggaacggcg tataagaaga ccaccccgac tatcgccgcc aaccagacca acgcgttaca
     5821 cagcggcgtc gcacggttca gcaataaacc gagcgccccc agaccgccga gcgccacaaa
     5881 agccgccgac aagacaatct cgttactcat cggcgaatgt ccgacgcgca gcagcatatt
     5941 cagcgcacgc aacggttgcc cgacgtggaa ggtaccgaca acgacgccaa tcccaaacag
     6001 gcacatcacc gagaacagac cgatagcctt acgccgcggc gcgaccagcc ccattgcgcc
     6061 gccaatcagc agcagaataa acgcgccgac cgcgctctgg gtaaagaccg taaaaaagac
     6121 cagcggtaac tcatgcatgg cgcacctccc gaatgttcat gattgcgcct tccgtatcgc
     6181 ccgtgggtct cgctttcgga tgcggtttaa taatgaggtt aggatgggtg aacgacgccg
     6241 aaggcagcgg cgcgatttga ttctccgtgc catattttgc ccgtaattca tcgacagggc
     6301 cgaaatccag cgctcgctgc gggcaagaat ccacacaaat ggggcgcaga ttgttctcca
     6361 gtcagtcaag acaaccgtcg catttacgca tcacgtttgc ctgcgtatca aactgcggcg
     6421 cgccgtaggg gcagcgcatt tcacaatagc gacagccgac gcatacgctg tcatccacca
     6481 cgaccagacc atcttctttg cgtttatgca tcgccccggt cggacagccg gagacacata
     6541 ccggctcatc gcaatggtta caagcaatag agaggtagta ggtaaaggtg tcgtgatgcc
     6601 agctttcccc ctctttcacc cagcttccgc cgccatattc atagacgcgg cgcagtttcg
     6661 ggccgacatc cagatcttta ttatccttgc agcttacctg gcaggtttta cagcctgaac
     6721 agcgcgagga gtcaacataa aagccacact gtttcatcgt acatcactcc ttaagcgcgt
     6781 ttaatttcaa ccagattggt atgctgcgga ttgcctttcg ccagcggcga agggtgatgg
     6841 ctggtcagcg tattgataca gccgccgaca tcaacaccgt tgccgtcaag ccgcgtccac
     6901 gcgccctgcg gcatcgccgc cacgccgggt aaaatgcgct gggtaacttt acagggaagc
     6961 tccaccacgc cgcggtcatt gaatacatgc acccgatcgc cggacttcag ttggcgggcg
     7021 ctggcgtcaa tcgggttaat ccagacttca tccggcaccg cctcatgcag catcagcaca
     7081 ttgctgtagg tcgagtgggt atgccctttg gtatggaaac cgcttaactg caacggatac
     7141 ttcgccgtca atgctttgtt aaggtgcgac tctttcgctg gacaaaattc cggcaatgcg
     7201 ggaattcgct cgccttctgg caacgtccac gcttgcgcca gatccgccag cgcctaggag
     7261 taaatttcaa ttttgcccga cggcgtggag agtggattag cctcggcgtc ggcgcggaaa
     7321 tcagcaaacg caaggctctg ctgctcggta gcgatacgct ggtcaatcac gcccatctct
     7381 ttcgccacgc tccactccgg caggtatgga cgtttttcac ggatctgctg atagtgcatc
     7441 tccgcccact gcgcctgagt tcggccctcg gtatattgct cgcgcagtcc aagatgcccg
     7501 gcgatatccg cgcagatgtc atacgtgctg cgcacttccc acatcggttt aacggttttc
     7561 tgaatcgcaa tcatatagtt atgcgatcct gccgcatagg agctgtccac caggtcttcc
     7621 gcctcaagat agctggtctc cggcaacagc agatccgcat acatcgcgct gggcgtcata
     7681 tggttttcaa tcacgataat ggtttcacac agcgattcat ccgcgagaat ttgacgggtg
     7741 cggtttgttt cgccgtgctg attaagcaaa gtattaccgg cctggttgaa aaacagctta
     7801 atcccggttt ttagcctgtc cgcgcctttt acgcccattg tcgtcgcggt cattttctcc
     7861 ggatgctgaa tggcgtccgt ccacagatag caaggaatag aggttgtgat cggattctta
     7921 ccgacaggca acaatggcac gccatacggc gtaccgtaag gccagttgcc attattggtg
     7981 ccgggccgcc cgaagtggcc ggttaacgct ggcagcgtct gaatagcacg cacggtttgt
     8041 tcgccgttgg catgacgctg cggcccccag ccctggcaaa tatagcaggc gcgcgcgagg
     8101 cgatttcgcg cgccagttgg cgaatacgcg ttgccggaat tccggtgata tccgccgccc
     8161 attccggggt tttcgcgata ccgtcatcgc ccgtgccaag aacataatct ttatagctgg
     8221 cgttaggcgc agccgtgtcc ggcaaggtgc tacggtcata gccgacgcaa tagcggttta
     8281 ccagcgcctc gtcgagaagc tgttcggtaa tcagcgtatg cgctatgccg gcgactagcg
     8341 cggcgtccgt ggttgggcga atcggtagcc attcggcgtg ttcggtaatc accgaatcgg
     8401 tatagcgcgg atcgataata atgactcggg ctttcgaggt ctccagcgcc cggcgcagct
     8461 cttcaacctg accgccgccg gacatccgcg tttctgagag attcaggcca aatagcacca
     8521 ccagatcgga atgcgcgatc tgcgtaaaat ggctaccgac ataatcaccg tgggtataag
     8581 gcgtggcggc ggcgatttgc gccgtggaat aggtgttgtg ataatttaaa taaccgccgg
     8641 tgagatttag taatcttatc caggcgggtc taccctgcgt gtgataatac gcgccggatt
     8701 gataattata ataaatagct tcccggccat atttttcgct aacgcgcgtt aattccgccg
     8761 caataaaggc tgtggcctca tcccatgaaa tacgtttaaa ttttccttcg ccgcgttttc
     8821 ccactctttt catcggatac ttaatgcgat ccgggctata aacgcgccag cgactggaac
     8881 gcccgcgcag gcagggacga atctgatgct cgccgaatac cgcgtcatct ttcgcgtctt
     8941 ccggttcaat acgcacaatg cgatcatttt tcacgataac cttaagcggg catcggctgc
     9001 cacagttgac cagacaggcg ctgtgcctga cggtttcgcc gttggcatcc ttcggtatcg
     9061 gggtatcctg cgcctgggca gtggtagcaa aaggcagcgt aatcgcctga cttagcgtca
     9121 ccgccgcccc tacttttgca gtagcgacaa tagcatcacg tcgggttatg gttgtgttca
     9181 gccatttttt atttccattt tttatttctc acattgcttc cat
//
LOCUS       DAJVKX010000157         9198 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.157, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000157 DAJVKX010000000
VERSION     DAJVKX010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9198
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.157"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..450
                     /locus_tag="OPY25_003943"
     CDS             <1..450
                     /locus_tag="OPY25_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929423.1"
                     /translation="ELGVSYNYKVTDHFVLQPGFIFESGPDTSIYKPYLRAQYNFDSG
                     VYMAGRYRYDYARKTANYNDDEKTNRFDTYIGYVFDELKLEYKFTWMDSDQIKFDNKK
                     TNYEHNVALAWKLNKSFTPYVEVGNVAVRNNTDERQTRYRVGLQYHF"
     gene            733..2013
                     /locus_tag="OPY25_003944"
     CDS             733..2013
                     /locus_tag="OPY25_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929424.1"
                     /translation="MIAKFFPWYSEITRPQKNALFSAWLGYVFDGFDFMLIFYIMYLI
                     KADLGLTDMEGAFLATAAFIGRPFGGALFGLLADKFGRKPLMMWSIVAYSVGTGLSGL
                     ASGVIMLTLSRFIVGMGMAGKYACASTYAVESWPKHLKSKASAFLVSGFGIGNIIAAY
                     FMPSFAEAYGWRAAFFVGLLPVLLVIYIRARAPESKEWEEAKLSGLGKHSQSAWSVFS
                     LSMKGLFNRAQFPLTLCVFIVLFSIFGANWPIFGLLPTYLAGEGFDTGVVSNLMTAAA
                     FGTVLGNIVWGLCADRIGLKKTFSIGLLMSFLFIFPLFRIPQDNYLLLGACLFGLMAT
                     NVGVGGLVPKFLYDYFPLEVRGLGTGLIYNLAATSGTFNSMAATWLGITMGLGAALTF
                     IVAFWTATILLIIGLSIPDRLKARRERFQSTKEF"
     gene            2024..3130
                     /locus_tag="OPY25_003945"
     CDS             2024..3130
                     /locus_tag="OPY25_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCS0929425.1"
                     /translation="MMTKYGVIGTGYFGAELARFMSKVEGAKITAIYDPVNAAPIAKE
                     LNCVATSTMEALCTHPDVDCVIIASPNYLHKAPVIAAAKAGKHVFCEKPIALNYQDCK
                     DMVDACKEAGVTFMAGHVMNFFHGVRHAKALIKAGEIGEVTQVHTKRNGFEDVQDEIS
                     WKKIRAKSGGHLYHHIHELDCTLFIMDETPSLVSMAAGNVAHKGEKFGDEDDVVLITL
                     EFESGRFATLQWGSSFHYPEHYVLIEGTTGAILIDMQNTAGYLIKAGKKTHFLVHESQ
                     AEDDDRRNGNISSEMDGAIAYGKPGKRTPMWLSSIMKLEMQYLHDVINGLEPGEEFAK
                     LLTGEAATNAIATADAATLSSNEGRKVKLTEILG"
     gene            complement(3282..3418)
                     /locus_tag="OPY25_003946"
     ncRNA           complement(3282..3418)
                     /ncRNA_class="other"
                     /locus_tag="OPY25_003946"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(3467..3554)
                     /locus_tag="OPY25_003947"
     tRNA            complement(3467..3554)
                     /locus_tag="OPY25_003947"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3518..3520),aa:Ser,seq:gga)
     gene            3790..4728
                     /gene="ghrA"
                     /locus_tag="OPY25_003948"
     CDS             3790..4728
                     /gene="ghrA"
                     /locus_tag="OPY25_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HCS0929426.1"
                     /translation="MEIIFYHPTFNAAWWVNALEKALPHARVREWKVGDNNPADYALV
                     WQPPVEMLAGRRLKAVFVLGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEY
                     AASQVLHWFRRFDDYQALKNQALWKPLPEYTREEFSVGIIGAGVLGAKVAESLQAWGF
                     PLRCWSRSRKSWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPD
                     GAYVLNLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHI
                     AAVTRPAEAIDYISRTITQLEKGEPVTGQVDRARGY"
     gene            4813..5550
                     /locus_tag="OPY25_003949"
     CDS             4813..5550
                     /locus_tag="OPY25_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HCS0929427.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAEAKRKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRLVDGVGILRGIEANIKNINGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKETNTQAMIATIASGKVHIISHPGNPKYPVEVKAIAQAAAKHHVALEINNS
                     SFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTLGDFTECRKILDAVNFPEDR
                     ILNVSPQRLLAFLESRGMAPVPEFAEL"
     gene            5574..6128
                     /locus_tag="OPY25_003950"
     CDS             5574..6128
                     /locus_tag="OPY25_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCS0929428.1"
                     /translation="MNEFSILCRVLGSLFYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DDMLARLQKSCDITQISTDYNALFVGEECAVAPYRSAWVEGAEESEVRAFLTSRGMPL
                     ADTPADHIGTLLLAASWLEDQSAEDESEALETLFADYLLPWCNTFLGKVEAHAVTPFW
                     RTLAPLTRDAIGAMWDELQEEDEE"
     gene            6229..6711
                     /locus_tag="OPY25_003951"
     CDS             6229..6711
                     /locus_tag="OPY25_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HCS0929429.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGFKGLLISACTLLSGMVWALVIIHGSALAPHLEIVSYVLTGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWRLVLPSLALGLIFGYAMKNSGLWLASRREQHSANTAVTK
                     "
     gene            complement(6749..7582)
                     /gene="csgG"
                     /locus_tag="OPY25_003952"
     CDS             complement(6749..7582)
                     /gene="csgG"
                     /locus_tag="OPY25_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HCS0929430.1"
                     /translation="MPRLLILVAVLLLSGCLTAPPKQAAKPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAMNNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     IGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKADRQNDILVKYRELSVPPE
                     S"
     gene            complement(7609..8025)
                     /gene="csgF"
                     /locus_tag="OPY25_003953"
     CDS             complement(7609..8025)
                     /gene="csgF"
                     /locus_tag="OPY25_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HCS0929431.1"
                     /translation="MRVKHAVVLLMLFSPLTWAGNMTFQFRNPNFGGNPNNGSFLLNS
                     AQAQNSYKDPAYDNDFGIETPSALDNFTQAIQSQILGGLLTNINTGKPGRMVTNDFII
                     DIANRDGQLQLNVTDRKTGRTSTIEVSGLQTQSTDF"
     gene            complement(8052..8447)
                     /gene="csgE"
                     /locus_tag="OPY25_003954"
     CDS             complement(8052..8447)
                     /gene="csgE"
                     /locus_tag="OPY25_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HCS0929432.1"
                     /translation="MKRYLTWIVAAELLFATGNLHANEVEVEVPGLLTDHTVSSIGHE
                     FYRAFSDKWESEYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPMKRDFEKTVVF
                     ALAQTEEALNRRQIDQTLLSTSDLARDEF"
     gene            complement(8476..9102)
                     /gene="csgD"
                     /locus_tag="OPY25_003955"
     CDS             complement(8476..9102)
                     /gene="csgD"
                     /locus_tag="OPY25_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HCS0929433.1"
                     /translation="MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQ
                     RSLEDISAGCIVLMDMMEADKKLIHYWQDNLSRKNNNIKTLLLNTPDDYPYREIENWP
                     HINGVFYATEDQEHVVSGLQGILRGECYFSQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVS"
BASE COUNT         2289 a         2010 c         2350 g         2549 t
ORIGIN      
        1 gaactgggcg taagttataa ttataaagtt acggaccatt ttgttttgca gcctggattt
       61 atatttgaaa gcggtccaga cacttcaatt tataagcctt atttaagggc gcaatataat
      121 tttgattctg gtgtttatat ggctggtcgt taccgttatg actatgcaag gaagacagct
      181 aactataatg atgatgagaa aacgaataga tttgatactt atataggtta tgtttttgat
      241 gagttgaaat tggaatataa atttacctgg atggatagcg atcaaattaa atttgataac
      301 aaaaaaacaa actatgaaca taatgtggct ttagcctgga aactgaataa gtcatttaca
      361 ccatacgttg aggtcggaaa tgtagcggtg agaaataata ccgatgagag acagacccgt
      421 tatcgcgttg gattacaata ccacttttga gaaaggttaa agagttactg tactaatctt
      481 tgcttagtat tcatatcgat aatcttatag cccgtagcta cgttacagaa cgttagactt
      541 tgtcttgagt attcacgtcc ttaacgtagc tacgaacaag gatgataaac aatgaatata
      601 cgccttacat agctacgatc tcaggcggtt gtcggaaagt gccggttgat agtgtcttat
      661 tcggcaattg atatgactta aaaattaatt ccgtaagcat ttcagacggt aacagcaaat
      721 aagggtttta ttgtgatagc aaaattcttc ccgtggtata gcgagataac acgtccacaa
      781 aaaaatgctt tattttcagc atggctgggt tacgtttttg atggcttcga ctttatgctg
      841 attttctaca ttatgtatct gatcaaggct gacttaggat tgacagatat ggagggcgca
      901 ttccttgcca cagcggcctt tattgggcga ccatttggcg gggcgctatt tggtctgctg
      961 gcagacaaat ttggccgtaa gccgttaatg atgtggtcga tagttgccta ttctgtaggt
     1021 acagggttaa gtggcctggc ttccggtgta attatgctga cgcttagtcg ttttattgtc
     1081 ggtatgggga tggcggggaa gtatgcttgc gcttctactt atgccgtgga aagttggcca
     1141 aagcatttaa aatctaaagc gagcgcattt ctggtttcag gtttcggtat tggtaacatc
     1201 atagcagcct attttatgcc gtcatttgcc gaagcgtatg gttggcgtgc tgcttttttt
     1261 gtcggtttgc tacccgttct tttagtaatc tacatccggg ccagggctcc tgaatctaaa
     1321 gagtgggaag aagccaaact cagtggtctc ggaaagcatt cacaaagtgc ctggtcagtt
     1381 ttctctttgt caatgaaagg gctatttaat cgagctcaat ttccactgac attatgtgta
     1441 tttattgttc tgttctctat tttcggcgca aactggccga tctttggtct actgcctaca
     1501 tatttggcgg gagagggctt tgatacgggc gtggtctcta atttaatgac ggcggcggca
     1561 ttcggcactg tattgggaaa tatcgtttgg ggtctgtgcg cagatagaat tggtttgaag
     1621 aaaacgttca gcattggtct tctcatgtcc tttttattca ttttcccgtt attcagaatt
     1681 ccgcaagata attatttact gctgggcgca tgtttattcg gtttaatggc gactaacgta
     1741 ggtgttggcg ggctggttcc caaatttctc tacgactact ttcctcttga ggttcgtggt
     1801 ttgggtaccg ggcttattta taatcttgct gcgacatcag gcacattcaa ttcaatggcg
     1861 gcgacctggc ttggaataac aatggggcta ggcgctgcgc taacgttcat tgttgctttc
     1921 tggaccgcaa caattctact cattattggc ctatccattc cggatagact aaaagcacgt
     1981 cgtgaaaggt ttcagtcaac aaaagaattt taatagagga taaatgatga cgaaatacgg
     2041 tgttataggt acaggttatt ttggcgctga actggcgcga tttatgtcta aggttgaagg
     2101 ggcgaaaatc actgcgattt acgatccggt aaatgcggct ccgatagcga aagagctgaa
     2161 ctgtgtcgcc acttcaacga tggaggcgct ttgtacccat cctgatgtgg attgcgtaat
     2221 tattgcttca ccaaattact tacataaagc gccggtcatt gcggcggcta aagcgggtaa
     2281 acacgtgttt tgtgaaaaac ctatcgcctt aaattaccag gattgtaagg atatggttga
     2341 tgcctgcaaa gaagctggtg ttacctttat ggcgggtcac gttatgaact tttttcacgg
     2401 ggttcgccac gctaaagcgc tcatcaaagc cggtgaaatc ggtgaagtta cacaagttca
     2461 cactaaacgt aatggttttg aagacgtgca ggatgagatc tcatggaaga agattcgcgc
     2521 aaagtcaggt gggcatctgt accatcacat tcacgagcta gattgtacac tgttcatcat
     2581 ggatgaaacc ccatccctgg tttcaatggc ggcggggaat gttgcgcaca aaggtgaaaa
     2641 atttggtgat gaagatgatg ttgtcctaat cacccttgag tttgaaagcg gtcgtttcgc
     2701 gacacttcag tggggatcat cgttccacta ccctgagcac tatgtattaa ttgagggcac
     2761 gacaggtgca attctcattg atatgcaaaa cacggctggt tatctaataa aagcgggcaa
     2821 aaaaacacac tttcttgtgc atgaaagcca ggcggaggat gatgatcgtc gcaacggtaa
     2881 catatccagc gagatggatg gcgcaatcgc ttatggtaaa cccggtaaac gtacgccgat
     2941 gtggctctca tcaattatga aactggagat gcagtacttg catgatgtga taaacggtct
     3001 ggagccaggc gaggagtttg ctaaattgct aacgggagaa gcggcgacaa atgccattgc
     3061 taccgctgat gctgcgacgc tttcttcaaa cgaggggcgc aaagttaaac tcactgaaat
     3121 tcttggctaa aatttaaagc cggatggtgg tgttattggc cggtggcgct gcgcttatgt
     3181 agactggata aggcgcccgt gaactgtgcc gccatccggc aatggacggg ggcttaatgc
     3241 gaaaaaaagc ccgtacattc gtacgagctc tttcttaaat atggcggtga gggggggatt
     3301 gactcgctgc gctcgccctt cgggcagccc gttcgctgcg cgcccggtct gtccaactgg
     3361 ctgcgccagt tgtcgaaccc cggtcggtgg ttctcatccc cccttggttt gggggataca
     3421 tataagcaaa aagcctgtac ttctgtacag gctctcaact tgaagatggc ggtgaggggg
     3481 ggattcgaac ccccgatacg ttgccgtata cacactttcc aggcgtgctc cttcagccac
     3541 tcggacacct caccaaattg tcgctccagc attactggaa cgggcgctaa tgtagggaaa
     3601 tatcctttct acgtcaatca acttttttaa aaaaaagcgc ttttatacaa acttccatca
     3661 atctgtggct ttaataagcg aaaactgctt tttttgcccg cgccgggaaa tttgctatgc
     3721 tgcacatccc gttgaaaacg ctgataacag gcgcaatcac attccgcaca atactgctca
     3781 ggagataaca tggagataat tttttatcac ccgacattta acgccgcctg gtgggtaaat
     3841 gcgctggaga aggctctccc acatgcgcgc gttcgtgaat ggaaggtcgg tgataacaac
     3901 cccgcagact atgcgcttgt atggcagccc ccggttgaaa tgctggccgg aagacgctta
     3961 aaagccgtct ttgtgctggg cgcgggggtg gatgcaattc tgagtaaatt aaatgcgcat
     4021 ccggaaatgc tggacgcctc cattcctcta ttccgtctgg aagataccgg aatgggcctg
     4081 caaatgcagg agtatgccgc cagccaggta ttacactggt tccgtcgttt cgatgattat
     4141 caggcgctga aaaatcaggc gctatggaaa ccgttgccgg aatatacccg cgaagagttt
     4201 agcgtcggta tcataggcgc aggggtactg ggcgcaaaag tggcagaaag tctacaggcg
     4261 tgggggttcc cgttacgttg ctggagtcgt agccgcaaat cctggcctgg cgtggaaagt
     4321 tatgtagggc gtgaagaact gcgcgctttc ctgaaccaga cgcgggtgct gattaatctg
     4381 ctgccgaata cggcccaaac ggtaggaatt attaatagcg aattgttgga tcaattgccg
     4441 gatggcgctt acgtgctgaa tctcgcgcgc ggcgttcatg ttcaggaggc ggatctgctg
     4501 gctgcgcttg atagcggtaa gctaaaaggc gcgatgttgg atgtctttag ccaggaaccg
     4561 ttaccgcagg aaagtccatt atggcgccat ccgcgagtcg ccatgacgcc gcacattgcg
     4621 gcagtcaccc gtccggcgga agccatcgat tatattagcc gcaccattac ccagctggag
     4681 aagggagagc cggtgacggg gcaggtggat cgggcgagag gatattgata tcaacccggc
     4741 gcgggccggg tttcgctaaa aaacgctggc gatacctgct atccttgtcg gaaatgacta
     4801 caggagagag caatgtatcc cgttgacctg catatgcata ccgtcgccag cactcatgcc
     4861 tacagtactc tgagcgatta tatcgcggaa gccaaacgca aaggcattaa actttttgcg
     4921 attaccgatc atggtccgga catggaagat gcgccgcatc actggcattt tattaacatg
     4981 cgcatctggc cgcgtctggt tgacggcgtg gggatactgc gtggcattga ggcgaatatc
     5041 aagaatatta acggtgaaat tgattgttcc ggaaagatgt tcgactcgct ggatctgatt
     5101 atcgcaggct ttcatgagcc cgtttttgcg ccgcatgata aagaaaccaa tactcaggcg
     5161 atgatcgcga ccatcgccag cggcaaggtg catataatta gtcaccccgg aaatccaaag
     5221 tatccagtgg aggttaaagc catcgcgcag gcggcggcga aacaccatgt agcgctggaa
     5281 atcaacaact cttcttttct gcattcgcgt aaaggaagcg aagataattg ccgcgcggtc
     5341 gctgccgccg tacgcgatgc gggaggctgg gtagcgttag gctctgattc ccatacggcc
     5401 tttacgcttg gcgatttcac cgaatgccgg aaaattctgg atgcggtgaa ttttccggaa
     5461 gatcgaatcc tgaacgtctc tccgcagcgc ttactggcct ttctcgaatc acgcggtatg
     5521 gcgcctgtac cggaatttgc cgaactttaa tcgttattta cgggaagata tcaatgaatg
     5581 agttttcaat cctgtgccgt gtgctgggat cgttgtttta ccgccaaccg caagatcctt
     5641 tactggttcc gctgtttacg ttaatccgtg aaggtaaact ggcggcaaac tggccgctgg
     5701 agcaggatga catgctggcg cgtttacaga aaagctgcga tatcacgcag atttccactg
     5761 attacaatgc gttatttgtt ggggaagagt gcgcggtagc gccataccgc agtgcgtggg
     5821 tcgaaggcgc ggaagagtct gaggtgcgcg cttttttaac gtcgcgaggg atgccgctgg
     5881 ccgatacgcc tgccgatcac attggcactt tattgctcgc ggcctcctgg ctggaagatc
     5941 agtctgccga agatgaaagt gaagcgctgg aaaccttatt tgccgattat ctgcttccct
     6001 ggtgcaatac cttcctcggt aaagttgaag cccatgccgt tacgccattc tggcgcactc
     6061 tggcgccgct aacgcgtgat gcgatagggg ccatgtggga tgaacttcag gaagaagatg
     6121 aagaataatg tgatgtaaat caccattaac tgcaacgggt tttgcatcat tgcataaaat
     6181 gtgtgcgtga tctcattaat gtgccgcttt tctgttatga tgcgcgccat gaacatactt
     6241 ctttctattg ctatcactac gggcatcctt tctggaatat ggggatgggt ggccgtctcc
     6301 ctggggttac taagctgggc cggtttttta ggctgtacgg cttatttcgc ctgtccgcag
     6361 ggcggcttta agggattgtt gatttccgcc tgtacgctgt taagcggtat ggtgtgggcg
     6421 ctggtcatta ttcacggtag cgcgttggcg ccgcatctgg aaattgtcag ttacgtgttg
     6481 acggggatcg tggcattcct gatgtgtatc caggcaaagc agctattgct ttcttttgtt
     6541 ccgggaacat ttatcggcgc ctgcgcgaca tttgcagggc agggtgactg gcggttggta
     6601 ttaccgtcgc tggcgctggg gctaatcttt ggctatgcca tgaaaaatag tgggctatgg
     6661 ctggcatcac gccgcgagca acattcagcg aatacggcgg tcacaaaata aaaaagcgtg
     6721 gggttttccc cacgctttgt cgtattcatc aggattctgg cggtactgac agctcacggt
     6781 atttcaccag aatatcattt tgcctgtccg ctttattctg caaatcccac agtccgcgat
     6841 cgataccatc attaatgagg aagataacgc cggtttcaat ggctgacatc agacacagca
     6901 tcaccggttc gttcgaggta tagccgattt cgccttccag taagcgctgg taatcaataa
     6961 aacggaacac gcctgcctgt acttcatagg aaaggatcgt tttactggtg ttcaccgaag
     7021 aaaggatctc gcccgtactg acgttaacca cgcgcaggtt gacagcaatc tgatccagct
     7081 gatactgcgt atcggcgcca ataccgaaat atcttgcgcc gaccccgccg gatttgacgt
     7141 tactttcata accaataata gaaccttcca ccataatatt tgccgccgtc aacgactgaa
     7201 gcgggatacg gttattcatc gccacggtgc cgttttcctg ggctgcgcga ataattttcc
     7261 gttcattcaa aagattctgt aagccttgtc gttctagtgg gataaaccag cgcgaatctt
     7321 tcagcgcggt gaccaacata gcggtggcgc tctgcggcac agccgtggaa aagttacttg
     7381 ccgggtaagg tttaaattgg cccgtttcat cctgaatgtt atataccgaa acaaagatct
     7441 taccggtggg agcaggtaag tgcgtcaaat ctttgtaact ttgtgcgcgg ggcattaatg
     7501 tcggtttcgc agcttgtttc ggcggggcag ttaagcatcc gctcaacaat aaaacggcaa
     7561 ccaaaataag taagcgcggc atgatttata tcctttagtg actgtagctt aaaaatcggt
     7621 tgactgagtt tgtaaacctg acacttcgat ggtcgaggtt cttcccgttt ttctgtccgt
     7681 gacgttgagc tggagctgtc cgtcgcgatt agcgatatcg ataataaaat cattggtcac
     7741 catacgtcct ggttttccgg tattaatatt ggtcaacaag ccgcccagaa tttgcgattg
     7801 aatagcctgc gtaaagttat ccaacgctga gggggtctcg ataccaaaat cgttatcata
     7861 agcggggtct ttatatgaat tttgcgcctg ggcgctattc aataaaaagg aaccgttatt
     7921 ggggtttcca ccaaagttag gattacggaa ctggaacgtc atatttccag cccaggttaa
     7981 tggcgaaaaa agcatgagca gcactactgc atgtttaaca cgcatgacag cctccggata
     8041 aaaatcatgt tttagaattc atcacgcgct aaatcactcg tacttaatag cgtttgatct
     8101 atttgtcggc gatttaatgc ttcctctgtt tgcgctaatg cgaagacgac ggttttctcg
     8161 aagtctcttt tcattggaaa taaaaaggtc tggaaaataa cgtcctgatt taccgttatg
     8221 gtgatccagc ttccccaacg cgcactgggt ctttcattaa tggtcagatt gccggtgtat
     8281 tcgctttccc atttgtcgct gaatgcacga tagaattcat gtcctatcga agagacggta
     8341 tggtcggtta acaatccggg aacctcgact tcaacttcat tggcatgcag gtttccggta
     8401 gcgaacagta actctgctgc tacaatccag gtcagatagc gtttcatggc cttaccgcct
     8461 gagattatcg tttgctcatg aaactgcctg ggtgcgattt ttgacagcta tctttttgaa
     8521 aagattataa agatgtgtct taaccgtatt ctcgctgata aatagcgacc tggcgatttc
     8581 attattagag gcaccaatac gtaacttatt gaggatctct ttttcgcgat gagtgagtaa
     8641 tgcggactcg gtgctgttgt agcggtaatt tcctgagtgt gtaatcaggt aactggctaa
     8701 tttttgtgaa aaatagcatt cgccccgcag aataccctgt aatccgctga ccacgtgttc
     8761 ctggtcttca gtggcgtaaa acacgccgtt aatatgaggc cagttttcaa tttcacggta
     8821 gggataatcg tcaggggtat ttaacaataa tgtttttata ttattgtttt tgcggcttaa
     8881 attatcctgc caatagtgga taagcttctt atccgcttcc atcatatcca ttaaaacaat
     8941 gcaaccggct gagatatctt ccagagaacg ttgaatatta tgcagttttc cggttatggc
     9001 cagcgattgc tttaaatgtt gcaataatgc cgtagcttgc agagatggct ttgtgatcaa
     9061 caatagtgtg tgaccatgac tactatggac ttcattaaac atgatgaaac tccacttttt
     9121 ttaatcgcac atctgacagc tgcccccata aaataaaggc accagaagta ctgacagatg
     9181 ttgcactgct gtgggttg
//
LOCUS       DAJVKX010000158         9164 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.158, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000158 DAJVKX010000000
VERSION     DAJVKX010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9164
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.158"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            90..1094
                     /locus_tag="OPY25_003956"
     CDS             90..1094
                     /locus_tag="OPY25_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCS0929434.1"
                     /translation="MMKEKKTLLNNNENGTGLPSKPSIMSENKLQNTVFSAIGSASPA
                     HKLVQGSSAAAFLKNHESLLAGTAVSSAFATQKLAQGSSVAAFLKSHESLFASTAVSS
                     AFAAQKLVQDSGITALFKKQGGIFNENYFATSIAKQLEKLDATEIQTLQEAAILFSRS
                     PQGAAIIATNIHAVEVKEPDALTKLKNYIEKSPITSNFRKLPLLVQLIIIYLVTTMYS
                     VVVDKNKELAMNLMEQAQQYVSKSISPRTHFKELTKQLPREVDISTLKHIRIITGENV
                     RLRNTPSMQGDVLVKLEKYTPVIVIDKSDRKWLYVQLSFGEQKIYGWVNRSYTKAINH
                     "
     gene            1179..1448
                     /locus_tag="OPY25_003957"
                     /pseudo
     CDS             1179..1448
                     /locus_tag="OPY25_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(2075..2857)
                     /locus_tag="OPY25_003958"
     CDS             complement(2075..2857)
                     /locus_tag="OPY25_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase domain-containing protein"
                     /protein_id="HCS0929435.1"
                     /translation="MGILAQEMKRLAQQAGGSHKTVHDRIKLAQGITKRSLQNEMAAV
                     RCILKQAGRDRLAQSERLNNRSLGLSGASRNGTKLAITPEHYRDVLETARVKDPGMAA
                     ALELSKLMGLRSQEAVQSVQSLKTWRQALDRGDTRLTVVFGTKGGRPRETIILDAVAV
                     RKALDNALAVAEDRHDRLIDKPDLKTAMKYWHSQASRLGLTGAYSPHSLRYAWAQDAI
                     RHYLAQGFSEKEALAMTAMDLGHGDGRGRYVAQVYGRKDGGD"
     gene            3127..3321
                     /locus_tag="OPY25_003959"
     CDS             3127..3321
                     /locus_tag="OPY25_003959"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929436.1"
                     /translation="MSESSHELAQLSCLVQVEKAACVTFPLYAVKVTHWTGAVSENLS
                     LVQFYDHAAAKPAVFAGRSP"
     gene            complement(3714..3935)
                     /locus_tag="OPY25_003960"
     CDS             complement(3714..3935)
                     /locus_tag="OPY25_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0929437.1"
                     /translation="MTQQDWHPADIIAGLRKRGTSLAALSRQSGLASSTLANALIRHW
                     PKGERLIAEALGIAPEQIWPSHYRKPENY"
     gene            complement(3932..4393)
                     /locus_tag="OPY25_003961"
     CDS             complement(3932..4393)
                     /locus_tag="OPY25_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000246267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929438.1"
                     /translation="MATTLTQTHPLLSVPFNAATDFTVLAEHCKQFAEILIEHDDPTL
                     KMALCGRLNACLQLLQPSLLDPIPEHMMDSLIVDTLPTRSPRFDPECTELCNYCLALT
                     QVLTGQGLLPETRNYLGCLLYDLIHYFSDEITAPRWLRTADGVKFIDEVTA"
     gene            4940..6613
                     /locus_tag="OPY25_003962"
     CDS             4940..6613
                     /locus_tag="OPY25_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929439.1"
                     /translation="MNSIFYLERHFTHGDRTYTETELLAASTHVVVLAEPGGGKTELM
                     KSLARKLNTTVLNASVFAYAGADKENSALVIDAVDEVARIDQSGIHKLLALARTSKPT
                     RVIMSSRSSEWGQACTSIFEKFLGFSPMVVRLKEFDQDEQHAIFKHHAPEEDFFAFQT
                     EVTRFSLDMLLPNPQFLKMFTDAYLESGRRFADKRSIFALAVERLAKEVNPDIPKAPV
                     SLSVAQKISFSAEVYAKLLLSGAEGVSTIDVTANRMYPMLPALFSSSAACYDILSTQL
                     FKPGDKEDQHRPVHKIVAEYCAADYLIKRIADPVDVLTLPKCLPVIAPNGIARDELRG
                     LLGWMAALGNRSVQGSIIELDAYAVLANGDPSQLERSSKRQLLYQLKEIEAADPYFRR
                     SDFWRRFSAAGFFTQDVVEEIKPLLTMGNDGHLRDLILELLADSPVNSQLVPELSQLT
                     LNPNESEHIRTLASRCLLNIKEYDCIGALAVLIFEASNISLNIAANVIEVTGPEKFDH
                     RYLSGFFRVCANLYPGHEEQFERVVGLVILLKSSFPVFHCILSNFFWTN"
     gene            6694..8979
                     /locus_tag="OPY25_003963"
     CDS             6694..8979
                     /locus_tag="OPY25_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929440.1"
                     /translation="MVDRYFELAQAPFDPVRIWQWIGNLNFHHQCQADQSKSVQVLRE
                     NDTLRQGIIAYVFGPLTDRNEIFNTRVEKFDGHLHSHSGLHLWRNDYKFILNLAFEAD
                     NVDLWASFLVNHQRYRNKEEQGPDDLRAQMRRHALSKPAFMREWARYNNAMKLSGQKS
                     QLRRFRHSRKMKRRDRKQREIHARNIKFVNENRDIVERGRHWRCLLRFAELVLMHPER
                     IELEFGDEKLVRTALRNCLDFITPEVPTLPELAALQCESKYRHSETVLYAACLEILRA
                     EGNLECVNIELLTALRTNIHRGYHSVSKEERDALQTEIDRLIFPYSESAEKYLRQYVE
                     PQLTQPCPHPEIGVLSRQEVFRHSRAKLSIEWLRRFPDVSLNSVDTLFEIAAQYGDRE
                     NLKEIIAERCSEMMSGWPNPKENEDIERKRIFWLVREFYFMENIADTYWAWLKSDKNN
                     LLHFYERSGRMNRSEHRAWPELASIKVEAILDAFIEHWPRVDLPDSWGSDSPKEEKAY
                     RFLTDLIWSINSDTSDDAIPVLDRLLNDPRFTNLHKELQSIYADQIRKKALRDFEPPT
                     PDEIVQRLDCDSVVTVEGLRQLVLQELHDFQKAIDGGEFNSADRFYEKNERLDEVKST
                     EIIAERLSLRLQPQGIAITPEHQLKGQNRSDFTASKLIGGRRRLLVTEVKGQWHRELY
                     SAASAQLYDRYSIHPDAEQQGIFLVIWFGESETVAGRKTHGIKTAQELKISIEAVLPA
                     DLRDLIDVFVLDVSRNGGHQR"
BASE COUNT         2520 a         2180 c         2155 g         2309 t
ORIGIN      
        1 cgaatgattg cccacacagt gttatgtcct atacgataaa ttgaaaaaac cttatattat
       61 caataaaaat ccgtcattca ggatgtgaaa tgatgaaaga gaaaaaaaca ctgctcaaca
      121 ataatgagaa tggaactggc ttaccatcca agccctcaat tatgagtgaa aataaactcc
      181 agaacacagt gttttccgct attggcagtg catccccagc tcacaagctg gtacagggct
      241 ccagcgctgc cgctttcctg aaaaaccatg aatcacttct tgccggtacc gctgtcagca
      301 gcgcattcgc aactcagaag ctggcacagg gctccagcgt tgccgctttc ctgaaaagcc
      361 atgaatcact ttttgccagt accgctgtca gcagcgcatt cgcagctcag aagctggtgc
      421 aggactcggg cattaccgct cttttcaaaa agcagggggg gatattcaac gaaaattatt
      481 tcgctacaag cattgctaaa caattagaaa aattagatgc aaccgaaatt caaacattac
      541 aggaagcggc cattctattt tcacgctcac ctcaaggtgc agcaattatt gcaacaaata
      601 tccatgcagt agaagtaaaa gagcctgacg cattaacaaa attaaaaaat tatatcgaaa
      661 aaagccctat aacttcaaac tttagaaaat taccattatt agtacaactc atcatcattt
      721 atcttgtaac caccatgtat tcagtcgttg tggataaaaa caaagaatta gcaatgaatt
      781 taatggaaca agcgcaacaa tatgttagta aatctatatc accaagaact cattttaaag
      841 aattaacaaa acagttaccc cgcgaagttg acattagcac attaaaacac ataagaataa
      901 ttactggaga aaatgtccga ttacggaaca caccatcaat gcaaggcgat gtattggtta
      961 agttggaaaa atatactccc gtgatcgtta tcgataaaag tgacaggaaa tggttatatg
     1021 tacaactgtc attcggagaa caaaagatct atggttgggt caatcgttcc tatacaaaag
     1081 caataaatca ttaagtcata aaatttgaat gaattctcat tcctaatgaa taagtataaa
     1141 atacttttag ccacccgact tctaagtgca gatcgggtgg ttacgacacc aaaaccgaag
     1201 tctgtggtca tggcttccgc acaatggcct gtagcgccct gaacgagtct gcgctgtggt
     1261 ctaaggacgc catcgagcgc cagatgagcc acaaggagcg caacggcgtg cgtgcggcat
     1321 atgtacataa agcggagcat ctggaagcgc gtatggagat gatgcagtgg tggtcggatt
     1381 atctcgacat gagccgcgag gggtacgttg cgccctatat ttatgcgcag cggcataagg
     1441 cggcctgagc cagcggcaat ataatttgtt gataatgaaa aagcagatcc tgattgaatc
     1501 cgaatctgct ttttgtattg aaaggaatta ccttgcattt tttggttgtt aataggaaag
     1561 cgtacaaaat tattctacgt agaataattt tgtacgaaaa tctatcaata tttcgcgaat
     1621 caataggtaa atatagaaaa ttatttgagg agaataattt caggcgatag cagccagaca
     1681 atctgcacca gaaactgatt tgccgatacg ccataactgc accagttcag tgtcatcgtt
     1741 tatctgcacc agtctgccgt cgcctgtcta tgtcaggatt gcgccagata ccaccggata
     1801 aataccgatc tgcgccagct ttatcctttt aagccctttg gccttttccg gtctggcgct
     1861 gttaccctta gccgcccttt acctttatct ggccttttcc cttttgctgg cacaatcacc
     1921 agaaaaaaat aacggaatgc tgcaccagaa gcctgttaat aggctagacc atttagaaac
     1981 atcgttatta aaaggaaacc gtacaaaaaa ttttgccccc aaaatttttt gtacgaaaac
     2041 cgatggataa cctcatattg caagtctgaa gctatcaatc accaccatcc tttctcccgt
     2101 aaacctgcgc cacataccgt ccgcgtccgt cgccgtgccc caaatccatc gccgtcattg
     2161 ccagcgcttc cttctcacta aatccctgcg ccagataatg acggatcgca tcctgcgccc
     2221 acgcatagcg caacgagtgc ggggaatatg cgcccgttaa gccgagacgt gacgcctgac
     2281 tgtgccagta tttcatcgcg gttttcagat ccggcttatc tatcagcctg tcgtgacgat
     2341 cttctgccac agccagcgca ttatccagcg cttttctgac tgctaccgca tcaagaataa
     2401 tcgtctcgcg gggtcgcccg cctttggtgc caaacactac ggttaagcgg gtgtcaccac
     2461 gatccagcgc ctgccgccac gttttcagcg actgtacgct ctgcaccgcc tcctgcgagc
     2521 gtaatcccat cagctttgag agttccagcg ctgccgccat ccccggatct tttacacggg
     2581 ctgtctccag cacgtcacga tagtgctccg gcgtgatagc cagctttgta ccgttgcggg
     2641 atgcgccaga cagaccaaga gaacggttgt tcagccgctc actctgcgcc agcctgtcac
     2701 gcccggcctg tttcagaatg caacgtaccg ccgccatctc gttttgcagg gaacgcttcg
     2761 tgatgccctg cgccagctta atgcgatcgt gaacggtctt atggctgccg cccgcctgtt
     2821 gtgcaagccg cttcatttcc tgcgccagaa tccccatatt ttcccccttt catgattgcc
     2881 gcaaactcat cccaaaaaac caacactgat accgctttcc ccggcgcaca ggccgatagc
     2941 ccctgttttt ttgtcggggc tgcgaacgat acctgagcgc cggggcggca gccgttgagg
     3001 tgtggtgggg cttcggttgt gctctcagag cagccgcccg cttgtgcggg ttatcccccg
     3061 gatcgtccgg atccgcctcg gtatcggctc atgttctcct tatgggtaaa atggcctgaa
     3121 aaggcagtgt cagaatccag ccatgagctg gcgcagttga gttgtctggt gcaggtcgaa
     3181 aaggctgcgt gcgtcacttt cccgctttac gcggttaaag tgacgcactg gactggtgca
     3241 gtgtctgaaa atttatcgtt ggtgcagttt tacgaccacg cagcagcaaa gcctgctgtc
     3301 tttgcaggcc gcagtccgta aggtaaaagg cgcagagggt gtcagcagat acaggttagc
     3361 cgggaaaatt tcggcgcgga gcagattcag accagcaggc tggcgcagta aaggacatat
     3421 agtgttaaaa ctcgggcctc cgtcgcgatg ttctgcgacc cggtgtttgc agaggtctgc
     3481 accggtaaac ggatcaaccg tcctgataac aggcgcttct ttcaggttgt gaagcgttgg
     3541 gcgctgtcga cgacagcatg gagcaggagg gagactacgc cagtgccgct ggcgcagaaa
     3601 ggaaaaactg tttgtacgtc aaaaagatta tttgcgagcc tgaactgccg cgcttcgctt
     3661 gccttctccc gatcttctga cagcaaagcc atcagaagat cgggagagac gatttagtaa
     3721 ttttcaggct tgcggtagtg ggaaggccag atttgctctg gcgcaatacc caacgcttcg
     3781 gcaatcagcc tttcgccttt gggccagtgc cttatcagcg catttgccag cgttgaggac
     3841 gccagccccg actgacggga cagcgccgcc agcgaggtgc cccgttttct caaccccgcg
     3901 ataatgtcgg cgggatgcca gtcctgttgc gtcatgctgt cacctcgtca ataaacttca
     3961 cgccgtcagc ggtacgcagc cagcgcgggg ccgtgatttc atcagaaaaa taatggatca
     4021 ggtcgtacag caggcagcca aggtaatttc tggtttccgg taatagcccc tgtcccgtca
     4081 gcacctgcgt cagggcaagg cagtagttac aaagttcagt acattcggga tcgaaacgcg
     4141 gtgagcgggt ggggagcgta tcaacgatca ggctgtccat catgtgctcc gggatcggat
     4201 caagcagtga gggctgaaga agttgcagac aggcattaag cctgccgcaa agtgccattt
     4261 tcagcgtggg atcgtcgtgt tcgatcagga tttcggcgaa ctgtttgcag tgttctgcca
     4321 gtacggtgaa atccgtggcg gcattgaagg gaacggagag tagcgggtgt gtctgggtga
     4381 gggtcgtagc cataaggcat cctccgatga gcagtgttta tcaccaccac cggagaggct
     4441 aatctcatgg tggtggaacc ggacggggtt agccttaccg gcctcatcga caccggcgcg
     4501 ctttgcagcg cccccgcccg gcccaccatt gagatgtagc agaacgcacg acacaaaaaa
     4561 agcgcagacg cgcctttgtg tcgtcgatga agtcaatcag gaggctaatc ccggcacctg
     4621 aatttgcagg tgcgtgtaaa agataccgca attagccaat agcagcaagt gaggggttct
     4681 ggaagcagat cgcagaaaat aaaaattcca cagacaagac cgccataaca ggaaaggttt
     4741 attatctgtt agcccgcaca tcgctgtggc gaaatgtgat taatgtcaat aagttgtata
     4801 atgtgtacaa cagttgataa aacatcccac caacaaagaa taaatgccgt actatctctg
     4861 atataagcaa gaaaactcag gcgcagcttt cctttctgct ggaatatttg ggctattcaa
     4921 tacgaaaaat tttgtaacga tgaattcaat cttctatctt gaacgtcatt ttacgcacgg
     4981 tgacagaacc tacacagaga cagagttgct ggcggcatca acgcacgttg ttgtgttagc
     5041 agaacccggc ggcgggaaaa cggaactgat gaaaagcctc gctcggaaac tgaacactac
     5101 tgtcttaaat gccagcgtat ttgcttacgc aggagcagat aaagaaaata gcgcactggt
     5161 aattgatgcc gttgatgaag tcgccagaat tgatcaatca ggtattcata aactccttgc
     5221 tctcgccaga acatcaaagc cgactcgcgt aatcatgtca agtagatcaa gcgaatgggg
     5281 acaggcttgt accagcattt ttgaaaaatt tcttggtttc tccccgatgg ttgtgaggct
     5341 gaaagaattc gatcaagacg agcaacacgc tatctttaag caccatgcgc cagaagaaga
     5401 cttctttgca ttccagaccg aagtaacacg gtttagttta gacatgttgt taccaaaccc
     5461 tcagtttctg aaaatgttca ccgatgccta tttagaaagt ggcaggcgat ttgctgacaa
     5521 acgttcaatc tttgctttag cagtcgaacg actggctaag gaagtcaatc cagatatccc
     5581 gaaagcccct gtatctcttt cagttgcaca gaagatttca ttttctgccg aggtttatgc
     5641 caaacttctg ttgtcgggcg cagagggagt cagcaccatc gacgtgacgg caaaccggat
     5701 gtatcccatg ctgccagcgt tgtttagcag cagtgcggcc tgttacgaca tattgtcaac
     5761 tcagcttttc aagcccggcg ataaggaaga ccagcaccgc ccggtccaca agattgtcgc
     5821 tgaatactgc gcagcggatt atctcattaa acgaatagcc gatcctgtgg atgtcctcac
     5881 tttaccaaag tgcttgcctg ttattgcacc gaacggtatt gccagagatg agttgagagg
     5941 tctgctcgga tggatggcag cattaggcaa caggtcggta cagggatcca ttattgagct
     6001 tgacgcctat gcggtactcg caaacggcga tccatcgcag cttgaacgct catcaaaacg
     6061 acagcttctc tatcaactca aagagattga agccgcagat ccttactttc gtcggagtga
     6121 tttctggcgc cggttcagcg cggctggttt tttcacgcaa gacgttgttg aggaaataaa
     6181 gcctctttta acgatgggca atgatggtca tttacgtgat ttaattttag aacttctggc
     6241 agactctcca gtaaacagtc agttggtgcc tgaattgagc cagcttacgt taaatcccaa
     6301 tgagtctgaa catattcgaa ccctagcaag cagatgctta ctcaatatca aagaatacga
     6361 ttgcattggc gctttagctg ttttgatttt tgaggccagt aatatttcac tcaatattgc
     6421 agccaacgtc atcgaagtca cagggcccga aaaattcgac caccgatatc tctctggatt
     6481 cttccgcgtc tgtgcgaatc tctatcccgg tcacgaagaa caattcgaaa gagtggtcgg
     6541 cctcgttatt ttattaaaaa gctcatttcc tgtttttcac tgcatactct cgaacttctt
     6601 ctggacgaat taacctgtaa cctttattgc cattgtggga aagaatccta tgaatgtgat
     6661 tgtcgtaatg gaataagcaa gattgtcggt tcaatggtcg atcgctattt tgaactggct
     6721 caagcaccat ttgatcctgt gaggatctgg caatggatag gtaatctcaa ttttcatcac
     6781 caatgtcagg ccgatcaaag caaatcggta caagtgcttc gggaaaatga cacacttcgt
     6841 caggggatca ttgcctatgt atttgggcct ttaacggatc gtaatgaaat attcaacaca
     6901 agagtagaaa agttcgacgg gcatctgcac tcacattcag gccttcattt atggaggaat
     6961 gactataaat ttatcctcaa tctggctttt gaagcagata acgttgacct gtgggcgagt
     7021 ttccttgtca accaccaacg ttacagaaac aaggaagagc aaggccctga tgatttgcgg
     7081 gcacaaatgc gtcggcatgc cctctccaag cccgcattta tgcgtgaatg ggcccgatac
     7141 aacaatgcaa tgaaattatc cgggcagaaa agccaactcc ggagattcag acatagccga
     7201 aaaatgaaac gccgtgacag aaagcaacga gagatccacg ccagaaacat aaaatttgtt
     7261 aatgagaaca gagatattgt agagcgaggt cgtcactggc ggtgcctgct gcgttttgca
     7321 gaacttgtgc tcatgcatcc ggaaagaatt gaattagaat ttggtgacga gaaactggtt
     7381 cggacagcgt tgcgaaattg tctggatttt attactcccg aggttcccac tctacccgaa
     7441 ctagcagcac tgcaatgcga atctaaatac aggcattctg agacggtttt atatgccgcc
     7501 tgtctggaga ttctacgtgc agaaggcaat cttgaatgcg tcaatatcga gttgcttaca
     7561 gccttaagaa cgaacattca caggggatac cactcagttt cgaaagaaga acgtgatgcg
     7621 ctacagactg aaatcgaccg cctcattttt ccttatagtg aaagtgctga aaaatatctc
     7681 cgacagtacg ttgaacccca actcactcag ccatgccctc accctgaaat cggggtatta
     7741 agtagacaag aggtctttcg tcattcacgc gctaaacttt ccattgaatg gcttcgtcgt
     7801 tttcccgatg tatcccttaa ttcagtcgat acactttttg aaattgccgc tcaatacggc
     7861 gatcgtgaga atttaaaaga gattattgca gagcgttgct cagagatgat gtcaggctgg
     7921 cccaatccga aagaaaatga ggatattgaa cgcaaacgaa tattctggct ggtacgtgaa
     7981 ttctacttta tggagaacat tgcggatact tattgggcat ggttaaaatc tgataaaaat
     8041 aatttactgc atttttatga acgttctgga cgtatgaatc gaagcgagca ccgtgcctgg
     8101 ccggaactcg cctcaattaa agttgaagcc attttagacg ctttcattga acactggccg
     8161 cgagttgatc tacctgatag ctggggtagt gatagcccta aagaagagaa agcctaccgc
     8221 tttttgactg atttgatttg gtcaataaac tcggacactt ccgatgatgc aataccagtg
     8281 ctggaccgtc ttcttaacga tccacgtttc accaatctac ataaagagtt gcaaagcata
     8341 tacgctgatc agatcagaaa aaaagcactc agagattttg aaccaccgac gccagatgag
     8401 atagttcaac gccttgattg tgattcagtc gttaccgttg aaggcctgcg tcagttagtt
     8461 cttcaggagc ttcatgattt tcagaaagcg attgatggcg gggaatttaa ctcggctgat
     8521 cgcttctatg agaaaaatga acgcctcgat gaggtaaagt ccacagagat tattgcggag
     8581 cgcctgagtt taagacttca gcctcagggt atcgctataa ctccagagca tcagttgaaa
     8641 gggcaaaaca ggagtgattt cacagcatct aaattgattg gaggaagaag acggctgctg
     8701 gttacggaag tcaaaggcca gtggcacaga gagttatatt ctgctgcttc agcccaactc
     8761 tatgaccgtt attccattca ccctgatgcc gaacagcaag gtatctttct tgtcatatgg
     8821 tttggagaaa gcgaaaccgt tgctggccgc aaaacccacg gaattaaaac cgctcaggag
     8881 ctaaaaatta gtattgaagc agtactaccg gctgatctcc gtgatttaat tgatgttttc
     8941 gttttagatg tttcacggaa cggtggccac caacgttagc aatatagctc tcgctaatta
     9001 accagagatc gggttaatta gcgagagcca acaaaacacc gtaagtatta ccatgccacc
     9061 aagtgaatac cattggccat ctggaaaact ggattccttt attttgtttg ctttgtagct
     9121 cttatgtttt aaacataata taaccatgat ttgatatata tcaa
//
LOCUS       DAJVKX010000159         9124 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.159, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000159 DAJVKX010000000
VERSION     DAJVKX010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9124
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.159"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            12..323
                     /locus_tag="OPY25_003964"
     CDS             12..323
                     /locus_tag="OPY25_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929441.1"
                     /translation="MSTREDNATRSMGGKLALWVFYTFCGYFIWAMARCVWLMSAIQT
                     EPVLGPISTPGSATEKWLNALSLGVVWLILGSIAWYTRPRKNRGYPADTQPETRKHAR
                     M"
     gene            403..1098
                     /locus_tag="OPY25_003965"
     CDS             403..1098
                     /locus_tag="OPY25_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCS0929442.1"
                     /translation="MDSGYWQSQFEDWLRHHHQEQDAAHDIFHFRRVWATAQTLGENS
                     PVDWLVVLSACYFHDIVSLAKNHPQRHRSSILAAAETRRIFLRDFPDFPAEKLAGICH
                     AIEAHSFSAKIAPTTPEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDADDPFAN
                     RRPLNDKQFALDHFKTKLLKLPLTMQTERGKHLAQRNADFLVSYMAKLSAELKGDYET
                     RDDAVIQMFATYQ"
     gene            1172..2602
                     /locus_tag="OPY25_003966"
     CDS             1172..2602
                     /locus_tag="OPY25_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCS0929443.1"
                     /translation="MQENISVTHARNLIADDAGSEIQAMLSQLLEIYDVKTLVAHLNG
                     LGEQHWSPAIFKRVMMNAAWHRLSDNELSCLKTELPTPPAHHPHYAFRFIDLFAGIGG
                     IRRGFEAIGGQCVFTSEWNKHAVRTYKANYFCDPLQHRFNEDIRDITLSHREGVSDDE
                     AAEHIRQHIPQHDVLLAGFPCQPFSLAGVSKKNALGRAHGFACETQGTLFFDVVRIID
                     ARRPALFVLENVKNLKSHDQGNTFRIIMQTLDELGYDVADAADNGPDDPKIIDGQHFL
                     PQHRERIVLVGFRRDLNLKTDFTLRNIARCYPPRRPTLAELLEPVVEAKYILTPVLWK
                     YLYRYAKKHQARGNGFGYGMVYPDNPESVARTLSARYYKDGAEILIDRGWDMAKGEVN
                     FDDAGNQQHRPRRLTPRECARLMGFEAPQTYQFRIPVSDTQAYRQFGNSVVVPVFAAV
                     AKLLEPKIHQAVTLRQRETADGGRSR"
     gene            2583..3053
                     /locus_tag="OPY25_003967"
     CDS             2583..3053
                     /locus_tag="OPY25_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="very short patch repair endonuclease"
                     /protein_id="HCS0929444.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRLAGLLSAQGITFHTQDT
                     TLPGKPDFVVNDYDCVIFTHGCFWHHHHCYLFKVPATRTAFWLEKIGKNVERDERDIQ
                     RLQALGWRVLIVWECALRGRAKLSDAALAERLEEWICGGGASAQIDTQGIHLLA"
     gene            complement(3042..3962)
                     /gene="yedA"
                     /locus_tag="OPY25_003968"
     CDS             complement(3042..3962)
                     /gene="yedA"
                     /locus_tag="OPY25_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HCS0929445.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LSAGMLLMAFLLLRGEKLPPLRQTINAALIGLLLLAVGNGLVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSYFFGIKTRKLEWVGIAIGLAGIILLNSGGNLSGNPWGAILILIGSM
                     SWAFGSVYGSRIALPVGMMAGAIEMLAAGVVLLCAAFLSGEKLATLPGLSGFMAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGERLSPVEWAALGVI
                     VFAVVLVTLGKYLFPARAVITPCKTEDSRQ"
     gene            4132..5049
                     /locus_tag="OPY25_003969"
                     /pseudo
     CDS             4132..5049
                     /locus_tag="OPY25_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
     gene            5126..5311
                     /locus_tag="OPY25_003970"
     CDS             5126..5311
                     /locus_tag="OPY25_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodC family protein"
                     /protein_id="HCS0929446.1"
                     /translation="MVFSVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGFGVKREAFH
                     ENELVPGKERRVRDEAR"
     gene            5476..7179
                     /gene="yedQ"
                     /locus_tag="OPY25_003971"
     CDS             5476..7179
                     /gene="yedQ"
                     /locus_tag="OPY25_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
                     /protein_id="HCS0929447.1"
                     /translation="MPHETLLDNQGWFKKLARRFGPGHVVNTCFLIVMLFSTLLTWRE
                     VMILKDAYVASQRNHLGSVANVLDRQLQFNMDRLIFLRNGMHEALVAPLAFSALQSAV
                     TQFEQRRVRHFWQLELDKRRTLPLYGVSDQFVARTTLLSRESRDLANELTATLELGYL
                     ARSSAMLTLETMYVSRSGFYLSTLPTAYGSDIVSRYYQYVTQPWFIEQSQRRNPQRGV
                     RWFTSAQPYVADEQKKVTASLPLDHDNYWYGVLAMDIPVASLQQFLRDAAEKDIEGEY
                     QLYDNHLRLLTDSAPEQQTENTLNDRERALLAREIEKDTLGGLRLGTHYVSWERLDHF
                     DGVLLRVHTLREGIQGNFGSISIALTLLWGLFTAMLLISWGVIRHMVKNMFVLQNSPQ
                     WQAWHDPLTRLYNRGALFEKASRLAKRYREARQPFSVIQLDLDYFKSVNDRFGHQAGD
                     RVLSHAAGLIGSTIRAHDIAGRVGGEEFCIVLPGATKAQALQIAERIRQRINDKEILV
                     TKSTTLRISASMGISSAEEYGDYDFEQLQSLADKRLYYAKQSGRNRICASDATQEREK
                     K"
     gene            complement(7158..7973)
                     /locus_tag="OPY25_003972"
     CDS             complement(7158..7973)
                     /locus_tag="OPY25_003972"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HCS0929448.1"
                     /translation="MLSIHDPLLIFTDLDGTLLNSHTFEWQPAAPWLTRLHESGVPVI
                     LCSSKTAAEMLQLQTTLNLQGLPLIAENGAVIQLDVHWEDHPNYPRLIAGISHNEIRL
                     VLHKLREKEQFKFTTFDDVDDQVISEWTGLNRAQSALTRLHEASVSLIWRDSDERMAQ
                     FVARLNDLGLQFVHGARFWHVLDASAGKDQAANWLIEAYRRQWRARPLTLGLGDGPND
                     APLLDVMDYAVVVKGLNREGVHLRNDDPQRVYRSQNEGPDGWREGMDYFFSRS"
     gene            complement(8283..8510)
                     /gene="yodD"
                     /locus_tag="OPY25_003973"
     CDS             complement(8283..8510)
                     /gene="yodD"
                     /locus_tag="OPY25_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodD family peroxide/acid resistance protein"
                     /protein_id="HCS0929449.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQEDPERV
                     SVDGREYHTWHELAEAFELDIHDFSVTEVNR"
     gene            8639..8833
                     /gene="dsrB"
                     /locus_tag="OPY25_003974"
     CDS             8639..8833
                     /gene="dsrB"
                     /locus_tag="OPY25_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001736680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HCS0929450.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNESGHQDGIFVEKAEQD"
     gene            complement(8872..>9124)
                     /gene="rcsA"
                     /locus_tag="OPY25_003975"
     CDS             complement(8872..>9124)
                     /gene="rcsA"
                     /locus_tag="OPY25_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460935.1"
                     /note="with RcsB is a positive regulator of capsular
                     polysaccharide synthesis genes; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HCS0929451.1"
                     /translation="SGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDRMNIKAKT
                     VSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFANMR"
BASE COUNT         2186 a         2305 c         2513 g         2120 t
ORIGIN      
        1 cggagtaaag tttgagtacc agggaggaca acgccacccg tagcatgggc ggtaaattag
       61 cgttatgggt tttttatacc ttttgcggct acttcatctg ggcgatggcg cgttgcgtgt
      121 ggctgatgtc cgccatacaa accgagccgg ttctcggccc aatcagcact cctggcagcg
      181 caacggaaaa atggcttaac gcgctttcgc tgggcgtcgt ctggcttatt ctggggagta
      241 ttgcctggta cacccggcct cgcaaaaaca gggggtatcc cgccgacact cagccagaaa
      301 cgcgcaagca cgcaaggatg taaagtggtg gcggatatgt caggatagcg aaccctgtgc
      361 tcaggcatgt aataaaaatg gtctgctata aagagagggc gtatggactc aggatactgg
      421 caatcgcagt ttgaagactg gctacgtcac caccaccagg aacaggatgc cgcccatgac
      481 atcttccatt ttcgtcgtgt ttgggcaacc gcgcaaacgc tcggggaaaa cagtcctgtc
      541 gactggctgg tggtgctatc ggcatgttat ttccatgaca tcgtcagcct ggcgaaaaat
      601 catccgcagc ggcatcgttc ttccattctg gcggcggcag aaacccggcg tatttttctg
      661 cgggattttc ctgactttcc ggcagaaaaa ctggcgggca tttgtcatgc tatcgaagcg
      721 catagcttca gcgcaaaaat tgcgcctacc acgccagagg caaaaatcgt acaggatgca
      781 gacaggctgg aggcgttggg cgccattggt ctggcgcggg tcttcgcggt ctccggcgcg
      841 ctgggcgtcg cgctgtttga tgccgacgat ccctttgcca acagacggcc tcttaacgat
      901 aagcaattcg cgctcgacca ttttaaaacc aaactgctga aactgccgct gacgatgcag
      961 accgaacggg gcaagcacct ggcgcagcgt aatgcggatt ttctggtgtc gtacatggcg
     1021 aaactgagcg ctgagctgaa aggcgactat gaaacacggg atgatgcggt catccagatg
     1081 tttgctacgt atcagtaacc cctgccgctg aaacgtaaac cgcgtcattt tatgttagtc
     1141 tgtcggcaat tatttttggc cggttaaatg tatgcaggaa aatatttcag taacacacgc
     1201 ccggaacctc atcgccgacg acgccggaag cgagatccag gcgatgctga gtcaattgct
     1261 ggaaatctac gatgttaaaa cgctggtggc gcaccttaac ggcctgggcg aacagcactg
     1321 gagcccggcc atcttcaagc gcgtaatgat gaacgcggca tggcatcgtt tgagcgacaa
     1381 tgaactcagc tgtcttaaaa cagagttgcc gacgccgcca gcgcatcatc cacattacgc
     1441 ctttcgtttt atcgatctct tcgcgggcat cggcggcatt cgccgcggat ttgaagcgat
     1501 aggcggacag tgcgtgttta ccagcgaatg gaataagcac gcggtacgga catataaagc
     1561 gaactatttt tgcgatccgc tgcaacatcg ctttaatgaa gatatccgcg atatcacatt
     1621 gagccaccgg gaaggggtca gcgatgatga ggcggcggaa cacattcgcc agcatattcc
     1681 gcaacatgat gtcctgctgg cgggctttcc ctgtcagcca ttttctctgg cgggcgtttc
     1741 caagaaaaat gcgctgggcc gcgcccacgg ctttgcctgc gagactcagg ggacgttatt
     1801 ttttgatgtc gtaagaatta tcgacgcccg ccgccccgcg ctgtttgtgc tggaaaacgt
     1861 gaaaaacctt aaaagtcacg accagggcaa caccttccgc attattatgc aaacgctcga
     1921 tgaactggga tatgacgtgg cggatgccgc tgacaatggc ccggacgatc cgaaaattat
     1981 cgacgggcag cactttcttc ctcagcatcg ggaacgtatt gtgttggtgg gattccgtcg
     2041 cgatttaaac ctgaaaaccg attttacgtt acgcaatatc gcccgttgtt atccaccgcg
     2101 ccgtccgacg ctggcagaac tgctggagcc cgtcgtcgaa gccaaatata tcctgacgcc
     2161 ggtgctgtgg aaatatttat atcgctacgc gaaaaagcac caggcgcggg gaaacggttt
     2221 tggctatggc atggtttatc ctgacaatcc ggaaagtgtg gcgcgcacgt tatctgctcg
     2281 ctactacaaa gatggcgccg aaattctgat cgatcgtggt tgggatatgg cgaaaggcga
     2341 agtgaatttc gacgatgctg gcaaccaaca acatcgtccc cgccgactca cgccgagaga
     2401 gtgcgcgcgt ttaatgggat ttgaggcgcc gcaaacgtac cagttcagga tacctgtctc
     2461 ggatacgcag gcctatcgcc agtttggcaa ctccgtggtg gtgccggtat ttgccgcggt
     2521 agcaaagctg ctggaaccca aaattcacca ggcggtgacg ctgcgtcaga gagagacggc
     2581 agatggcgga cgttcacgat aaagccacgc gcagtaaaaa tatgcgcgcg atagcgaccc
     2641 gcgatacggc gattgaaaaa cgccttgctg gcctgttaag cgcgcagggg attacgtttc
     2701 atactcagga cacgacatta ccgggcaagc cggactttgt ggtgaatgac tatgattgtg
     2761 tgatttttac tcacggctgc ttttggcatc atcaccactg ttatctattc aaagtaccgg
     2821 ccacgcgaac ggctttctgg ctggaaaaaa tcggtaagaa cgttgagcgc gatgagcgtg
     2881 atattcagcg tttacaggcg cttggctggc gggtactgat cgtctgggag tgcgccttgc
     2941 gcgggcgagc gaaattgagc gacgcggcgt tggcggagcg cctggaagag tggatctgcg
     3001 gcggcggcgc cagcgcgcag atcgacaccc aggggattca tctactggcg tgaatcttcc
     3061 gttttacacg gtgtgatcac cgccctggcg ggaaacaggt acttacccag agtcactagc
     3121 actacggcaa acacaatcac gcccagcgcg gcccattcaa cgggcgataa cctctcaccg
     3181 cctaggccag tgccaagcaa cacggcgaca accggattca cataggcgta gctggtcgcc
     3241 agcgccggac tgacgttgcg aatcaggtac atataggcat taatggcgat aatagaaccg
     3301 aataacgcca ggtagccgac ggccataaac cccgataaac caggcagcgt ggcgagcttt
     3361 tcgccggaaa gaaacgccgc gcaaagcaat accacgcccg ccgccagcat ttcaatcgcg
     3421 cccgccatca tgcccacagg cagggcgatg cgcgagccgt aaacggaacc aaatgcccag
     3481 ctcatcgaac ctatcaggat caaaatcgcg ccccacggat tgccgcttaa attaccgccg
     3541 ctgttcagca gaataatccc ggcaagtcca atggcaatcc ccacccattc taatttgcgc
     3601 gttttaatac caaaaaagta gctaaagcac agcgtaaata gcgggacagt ggcgaccacg
     3661 acggcagcaa tgcccgatgg cacgttttga tgctccgcca ccgtcaccag accgttaccc
     3721 accgccagca gcagtaggcc aatcagcgcg gcgttgatgg tctggcgcag cggcggaagt
     3781 ttttcgccgc gcaacagcaa aaacgccatg agcaacatcc ccgccgagag aaaacgtacg
     3841 cctgccatca ttagcggcgg ccagctttca acgcctatgc ggataacaaa ataggtagac
     3901 ccccaaatga tgtacaaggc aaaaagcgcg ccaaaaagag gtaataactg ccggaaacgc
     3961 ataatcactc acggtgaaat aaaaagggtg aatatagtaa acgtcaaaat tattatgctg
     4021 gcgagcatta taattgtcct tttggaataa aaaggcgttg acccgcgccg ccggtttcgg
     4081 cattgcgcgt tttgctacat acttaacgtc ttagaagaaa agaccgagga aatcattttg
     4141 gcaggaagta gcttactgac attactcgac gatatcgcca cgctgctgga cgatatttcg
     4201 gtaatgggca aattggccgc gaaaaaaacc gcaggcgtac tgggggacga cctgtcgctc
     4261 aatgcgcagc aggtgaccgg cgttcgcgct aatcgcgagc tgccagtggt atggagcgtg
     4321 gcgaaaggat cattaatcaa caaggttatt ctggtgccgt tggcgctgtt gataagcgca
     4381 tttatcccgt gagccattac gcctttatta atgttaggcg gcgcgtttct ctgctttgaa
     4441 ggggtagaaa aagtcctgca tacctttgag gcgcgaaaac acaaagaaga cctggcggag
     4501 cggcaaaaac gtcttgaggc gctggctacg caagatcctt tggcctttga aaaagataaa
     4561 gtaaaagggg cggtccgtac cgatttcatt ctttccgctg aaattgtggc aattaccctg
     4621 gggattgtcg cgcaggcacc gctgcttaat caggtgttgg tgctggcggg gattgcgttg
     4681 gttgtgacca ttggcgtgta tggcctggtg ggtattattg tcaaactgga tgatatgggg
     4741 tactggctgg cggaaaagcg tagcgtgctg gcgcagggcg tcggtaaagg attactgatt
     4801 atcgcgccct ggttaatgaa agcattatcc attgtcggta cgctggcgat gtttctggtt
     4861 ggcggcggaa ttgtcgtaca cggtattgcg ccgctacacc atgccattga acattttgcg
     4921 cagcagcagg gggctttcat ggcgcatacg atccctgcgg ggctgaatct ggtgctcggc
     4981 tttattatcg gcgccattgt ggtggcgctg gtgaaaggtg tggcgaaaat tcgcggtgtt
     5041 tcgcactgat tttctacaat gaattatgca aaattgtcca tcctcgtcta aggtgaaaac
     5101 gtttcatctg atacaggagg caggtatggt cttttctgtc agtgaggaag ttaccgtgaa
     5161 agagggtgga ccccggatga tcgtcaccgg ttattccagc ggaatggtag agtgtcgctg
     5221 gtatgatggt tttggcgtaa agcgggaggc attccatgag aatgagctcg tgccaggcaa
     5281 ggaaaggcgc gtgcgggatg aagcccgatg acaaaacgcc cggttaatgc cgggcgtttt
     5341 gctgtggaga aaaagagtcg tcgcgctgcg acatgctgct acctggttat gccaggattg
     5401 agtggtatcc cttgatgagg tctggctacc gtaagccatc agggggcgtt gtatcaataa
     5461 ccaggagtta ccagggtgcc gcacgaaaca ctgttagaca atcaaggctg gtttaaaaag
     5521 ctggcgcggc gttttggtcc cggtcatgtc gtcaacacct gttttctgat cgtgatgctg
     5581 ttctcgacgc tacttacctg gcgggaagtt atgatactga aagacgcgta tgtcgccagt
     5641 cagcgcaatc atctggggag cgtcgcgaat gtccttgacc gccaactgca attcaacatg
     5701 gacaggttga tctttttacg caacggtatg catgaagcgc tggtggcgcc gctggctttt
     5761 tccgcattgc aaagcgcggt gacgcagttt gagcaacgac gcgtcagaca tttctggcaa
     5821 ctggagttgg ataaacggcg gacattgccg ttatatggcg tttccgatca atttgtcgcc
     5881 cggacgacgc ttctttcgcg ggagagtcgt gacctggcaa atgaattaac cgccacgctg
     5941 gagttagggt atctggcgcg ctcatccgcc atgctgacgc tggagacgat gtatgtttct
     6001 cgctcagggt tttacctctc aactctccct acggcgtacg gtagcgatat tgtttcccgt
     6061 tactatcagt acgtgaccca gccctggttt atcgagcaaa gccaacggcg taatccacag
     6121 cgcggcgtgc ggtggtttac ctccgcacag ccctatgttg ctgacgagca gaaaaaagtg
     6181 acagccagtc taccgctgga tcacgataat tactggtatg gcgtactggc aatggatatt
     6241 cccgtcgcgt cattacagca gtttctgcgc gatgcggccg aaaaggatat tgaaggggaa
     6301 tatcagctat acgataacca tctccgtttg ttgacggact ccgcgccgga acaacaaacc
     6361 gagaatacgt taaatgaccg tgagcgcgcc ttactggcgc gtgaaataga aaaagatacc
     6421 ctgggcgggc tgcgtttagg aacgcattat gtaagctggg agcggctgga tcattttgat
     6481 ggcgtcctgc tgcgcgtgca tacattacgt gaaggtatac aagggaattt tggcagtatt
     6541 agtatcgcgc tgacgctgtt atgggggctt tttacggcga tgctgttgat ctcctggggc
     6601 gttattcgac atatggtcaa aaatatgttt gttctgcaaa attcgccgca atggcaggca
     6661 tggcacgatc cgctgacccg gctatataac cgtggcgcgc tgtttgaaaa agcgtccagg
     6721 ctggcaaagc gctatcggga agcccgccag ccattttctg tgatacagct ggatttagat
     6781 tattttaaaa gcgttaacga tcgctttggc catcaggcag gcgatcgcgt gttgtcccat
     6841 gccgctgggc tcattggcag caccattcga gcgcacgaca tcgccggacg ggtagggggc
     6901 gaagagtttt gtatcgtgct gcccggcgcg acgaaagcgc aggcgctgca gattgccgaa
     6961 cgcatacgcc agcgcattaa tgacaaagag attctggtga cgaaaagcac gacgcttcgt
     7021 atcagcgcgt caatggggat cagtagcgcg gaggaatacg gcgactatga ttttgagcag
     7081 ttgcagtcgc tggccgacaa acggctttat tacgccaaac agtccggacg taaccgtatt
     7141 tgcgccagcg acgcgactca ggagcgggaa aagaaatagt ccattccttc gcgccagcca
     7201 tccggccctt cgttctggct acggtagacg cgctgaggat cgtcgttacg caaatgtaca
     7261 ccctcccggt ttagcccttt aacgacaacc gcataatcca tcacatccag taagggcgca
     7321 tcattggggc cgtctcctag ccccaacgtc agaggacgcg cgcgccactg ccgacgatat
     7381 gcttcaatta gccagttggc agcctgatct ttaccggcgg aggcgtccag cacatgccag
     7441 aaacgggcgc catggacaaa ttgcagtccc aggtcattta aacgggcgac aaactgcgcc
     7501 atgcgttcat cgctatcgcg ccagatcagc gacaccgacg cttcatgcag acgggttagg
     7561 gcagactgtg cccggtttag gcccgtccat tcgcttatca cctgatcgtc aacgtcatca
     7621 aacgtggtga acttaaactg ttccttttca cgcaacttat gcaggacgag gcggatttcg
     7681 ttgtgagaaa taccggctat caggcgggga tagttgggat ggtcttccca atgaacgtcc
     7741 agttggatca ccgcgccgtt ttccgcaatc agcggcagtc cctgtagatt taacgtcgtc
     7801 tggagctgga gcatttcagc cgcggtttta ctgctacaga ggatcacagg cacgccgctt
     7861 tcatgcaggc gtgtaagcca gggggccgcg ggctgccact caaaagtgtg gctgttcagc
     7921 aatgtgccgt ccagatcggt aaaaatcagc aaggggtcat ggattgagag cattttttcc
     7981 tcattttccg ttgcaacggc gggcttattt ccaggaaaaa tcctaaagca catccgaaag
     8041 aagtcgaacg ctaactggaa ccgatcccgt cgcttccagg cagcacatgc gttgtcacac
     8101 ttttgctacc gaactattag cgcgcttaat cattcatgta aaaaatattt acttgtcatg
     8161 caaaaaaatt gcagataaag taaatctcac atcagatttc ctggtgtaac gaattttcaa
     8221 gtgcttcttg cataagcaag tttgatcccg acccgtaggg ccgggatttt tttcggccat
     8281 ttttaacggt ttacttctgt tacactaaaa tcatgaatat ccagctcgaa tgcttcagct
     8341 aattcatgcc atgtatgata ttcccgtccg tctacgctca cccgctcagg atcttcctgg
     8401 ctacggtgaa cctcgctttc gctgatttca ttgatggccg ccagtagcgc atctacatcg
     8461 acgctcactt cgcgcttggc cgtatcactg tactcttttg ccgttttcat cttcactacc
     8521 tcacgggttc ctgacagcct aagtatagac cgttgagaaa accagcaaac acgccggcaa
     8581 ggcgctgtca gacgcagaaa attgttctac actggcacaa agcgacagga ggaaaatgat
     8641 gaaggtgaat gatcgggtaa ccgttaaaac ggacggcggt ccccgccgac cgggcgtggt
     8701 actggcagtg gaagaattta gtgaaggcac aatgtacctg gtttcgctgg aggattaccc
     8761 gctcggcatc tggttcttca atgagtcagg tcaccaggat ggtatttttg tcgagaaggc
     8821 ggagcaggac taattgagcc ggactggagg tacattgcca gtccggatgt ctcagcgcat
     8881 gttagcaaaa atgccgttag tgacgttatc tgtcagccgc actacgtgat agatcacttg
     8941 tttattatgc gtttttatct ttctttttat attcccctta tgggaggata ctgtttttgc
     9001 tttaatattc attctgtcag aaatctgaat ggttccctga ccttccatcc acattcgtaa
     9061 catgctggat tcagttcgac ttaacgataa tgttggtaaa tttatggttc ctgaaatacc
     9121 cgac
//
LOCUS       DAJVKX010000160         9097 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.160, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000160 DAJVKX010000000
VERSION     DAJVKX010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9097
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.160"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..1063
                     /gene="ompS1"
                     /locus_tag="OPY25_003976"
     CDS             <1..1063
                     /gene="ompS1"
                     /locus_tag="OPY25_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="porin OmpS1"
                     /protein_id="HCS0929452.1"
                     /translation="RYFSDNAGDDGDQSYARIGFKGETQINDMLTGYGQWEYNIKVNT
                     TEGEGANSWTRLGFAGLKFGEYGSFDYGRNYGVIYDIEAWTDALPEFGGDTYTQTDVY
                     MLGRTNGVATYRNTDFFGLVEGLNFALQYQGNNENGGAGAGEGTGNGGNRKLARENGD
                     GFGMSTSYDFDFGLSLGAAYSSSDRSDNQVARGYGDGMNERNNYAGGETAEAWTIGAK
                     YDAYNVYLAAMYAETRNMTYYGGGNGEGNGSIANKTQNFEVVAQYQFDFGLRPSIAYL
                     QSKGKDLGGQEVHRGNWRYTDKDLVKYVDVGMTYYFNKNMSTYVDYKINLLDEDDDFY
                     ANNGIATDDIVGVGLVYQF"
     gene            complement(1324..1512)
                     /locus_tag="OPY25_003977"
     CDS             complement(1324..1512)
                     /locus_tag="OPY25_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCS0929453.1"
                     /translation="MTNKIHFRCPCCHGSQYRTSTFDVTEQNPFGAKCIFCKSTMITF
                     DNVGLYIRSGQVPLDFRK"
     gene            complement(1523..1735)
                     /locus_tag="OPY25_003978"
     CDS             complement(1523..1735)
                     /locus_tag="OPY25_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCS0929454.1"
                     /translation="MTTKITGLVKWFNPEKGFGFITPKDGSKDVFVHFSAIQSNEFRT
                     LNENQEVEFSAEQGPKGPSAVNVVAL"
     gene            complement(2181..3449)
                     /locus_tag="OPY25_003979"
     CDS             complement(2181..3449)
                     /locus_tag="OPY25_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCS0929455.1"
                     /translation="MFALCDVNSFYASCETVFRPDLCGRPVVVLSNNDGCVIACSAEA
                     KQLGIAAGEPYFKQKERFRRSGVVCFSSNYELYADMSNQVMTTLEEMVPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGHEIRATVLKRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     DGVVDLSNIDRQRRLLALIPVEDVWGVGRRISKKLNALGIKTALDLSEQSTWIIRKHF
                     NVVLERTVRELRGEPCLELEEFAPAKQEIVCSRSFGERVTDYEEMRQAVYSYAARAAE
                     KLRGEHQYCCFISTFVKTSPFALNEPYYGNSAAVTLLTPTQDSRDIINAAVKCLDKIW
                     RDGHRYQKAGVMLGGFFSQGVAQLNLFDDNAPRAGSAKLMEVLDHLNAKDGKGTLYFA
                     GQGMSQQWAMKREMLSPRYTTRYSDLLRVK"
     gene            complement(3452..3871)
                     /locus_tag="OPY25_003980"
     CDS             complement(3452..3871)
                     /locus_tag="OPY25_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HCS0929456.1"
                     /translation="MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELL
                     VSHPSSTYFVKATGDSMIEAGISDGDLLVVDSSRNADHGDIVIAAIEGEFTVKRLQLR
                     PTVQLIPMNGAYRPIPVGSEDTLDIFGVVTFIIKAVS"
     gene            complement(3998..4159)
                     /locus_tag="OPY25_003981"
     CDS             complement(3998..4159)
                     /locus_tag="OPY25_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929457.1"
                     /translation="MGAGQKINCCQGNALARGDNLRCGTVDAVQKIWPPDWLKYAHMT
                     IQPENLQNA"
     gene            complement(4462..4551)
                     /locus_tag="OPY25_003982"
     tRNA            complement(4462..4551)
                     /locus_tag="OPY25_003982"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4515..4517),aa:Ser,seq:cga)
     gene            4640..5437
                     /gene="mtfA"
                     /locus_tag="OPY25_003983"
     CDS             4640..5437
                     /gene="mtfA"
                     /locus_tag="OPY25_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HCS0929458.1"
                     /translation="MIKWPWKAQEITQNEDWPWDDALAIPLLVNLTAQEQARLIALAE
                     RFLQQKRLVALQGFELDSLKSARIALIFCLPILELGIEWLDGFHEVLIYPAPFVVDDE
                     WEDDIGLVHSQRVVQSGQSWQQGPIILNWLDTQDSFDASGFNLIIHEVAHKLDMRNGD
                     RASGIPFIPLRDVAGWEHDLHAAMNNIQDEIDLVGESAASIDAYAATDPAECFAVLSE
                     YFFSAPELFAPRFPALWQRFCQFYRQDPSQRLRVSAAEGDYGEESEH"
     gene            5538..5613
                     /locus_tag="OPY25_003984"
     tRNA            5538..5613
                     /locus_tag="OPY25_003984"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5571..5573,aa:Asn,seq:gtt)
     gene            6161..6236
                     /locus_tag="OPY25_003985"
     tRNA            6161..6236
                     /locus_tag="OPY25_003985"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6194..6196,aa:Asn,seq:gtt)
     gene            complement(6371..6649)
                     /locus_tag="OPY25_003986"
     CDS             complement(6371..6649)
                     /locus_tag="OPY25_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929459.1"
                     /translation="MILHPAKALLCRGFITIAGDLSPIIASTSGNAPEGENIAPHFTL
                     LERLDPQARINKQIPTVRIDQLKGIIRRLDTEDFRVGQGYRVVTPLSN"
     gene            complement(6739..8193)
                     /locus_tag="OPY25_003987"
     CDS             complement(6739..8193)
                     /locus_tag="OPY25_003987"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HCS0929460.1"
                     /translation="MENKGTNLTPEQALDRLEELYEQSVNALREAIADYVDNGTLPDP
                     HARLNGLFVYPSLSVSWDGATPNPPKTRAFGRFTHPGCYTTTVTRPALFRAYLLEQLN
                     LVYHDYGAHIAIEASHHEIPYPYVIDGSALTLDRSMSAGLTRHFPTTELAQIGDETAD
                     GLFHPGEFYPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGIWITAETEAPEEAISDLAWKKHQMPAWHLVTADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKAVSGMPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
     gene            8239..8400
                     /locus_tag="OPY25_003988"
     CDS             8239..8400
                     /locus_tag="OPY25_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0929461.1"
                     /translation="MTAKEETKGVSVRAAAVNMNPLKRKENYLSATIIAQKEGYWYSH
                     LLSSLQLVI"
     gene            complement(8389..8715)
                     /locus_tag="OPY25_003989"
     CDS             complement(8389..8715)
                     /locus_tag="OPY25_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1493 family protein"
                     /protein_id="HCS0929462.1"
                     /translation="MLDNIEQQVYELVRPYAGTYLFNIKQVELTPEIDLDTDLSIDEL
                     EAEDLMNKFFEKLNVERGNFRIETYFPNHPFSWHPFKKTEPVPVPDFTISMLIESAKA
                     GKWLYD"
     gene            complement(8709..>9097)
                     /locus_tag="OPY25_003990"
     CDS             complement(8709..>9097)
                     /locus_tag="OPY25_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002211098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929463.1"
                     /translation="MIFCENTASQFGIGVADFGAVVALVSGRNNLWTRAKPAGATKGT
                     SYASRTARAVFKKSKFPFGISLPTWLGGYTPWTARRVMVRNIAPFVGRSIPLIGEIIL
                     AADVSQIAYRTIRDYNTIARGNDKLC"
BASE COUNT         2314 a         2272 c         2206 g         2305 t
ORIGIN      
        1 gcgttacttc tctgacaatg caggcgacga tggcgatcag tcctacgccc gtattggctt
       61 taaaggcgaa acgcagatca acgatatgct gaccggctat ggtcagtggg aatacaacat
      121 taaggtgaac accaccgaag gcgaaggtgc aaactcctgg actcgtctgg gctttgccgg
      181 tctgaaattc ggcgagtacg gctctttcga ttatggccgt aactatggtg ttatctacga
      241 cattgaagcc tggaccgatg cgctgccgga attcggcggt gatacttata cccagaccga
      301 tgtctatatg ctgggcagaa ccaacggcgt tgccacctac cgtaataccg acttcttcgg
      361 tctggtggaa ggcctgaact tcgcgttgca gtaccagggt aataatgaaa acggcggtgc
      421 tggtgctggt gaaggtacag gtaacggcgg caaccgcaaa ctggcccgtg aaaacggcga
      481 cggtttcggt atgtctacct cctacgactt tgacttcggg ttaagcctgg gtgcggccta
      541 ctcttcctct gaccgttcgg acaatcaggt tgctcgtggt tatggcgacg gcatgaatga
      601 gcgcaacaac tatgccggcg gtgaaaccgc tgaagcctgg accataggtg ccaaatatga
      661 cgcctacaat gtttacctgg cggccatgta cgctgaaacc cgcaacatga cctattatgg
      721 cggcggcaat ggcgaaggta atggcagtat tgctaacaaa acccagaact ttgaagtggt
      781 tgcgcagtac cagttcgatt tcggtctgcg tccgtccatc gcctacttgc agtctaaggg
      841 caaagattta ggcggtcagg aagtccatcg tggcaactgg cgttacaccg acaaagatct
      901 ggttaaatat gttgacgtcg gtatgactta ctacttcaac aaaaatatgt ccacctacgt
      961 tgattataaa atcaacctgc tggacgaaga tgatgacttc tacgcaaaca acggtattgc
     1021 aaccgatgat atcgtaggtg ttggtctggt ctaccagttc taagacgctt tatgttattc
     1081 aagcccgtgc ttagcgcggg cttgttatta tagggcaaga attaaataac ggataacggc
     1141 gcaaagacag gtgaccaggc ttcatcggat agatgaagac aacgtcgctc ttttcaggcg
     1201 ctgtctgcaa gagaaataac acctttgggg aaaggtaaat gccactatag atgatggatg
     1261 tcagcgtcta tagatgataa tcatccgggc ataaaaaaag ctcctgtacg gagctaatat
     1321 gaattatttt ctaaaatcta gcggaacctg tcctgagcga atgtataatc caacattatc
     1381 aaaagtgatc atggttgact tacaaaaaat acatttcgcg ccaaacgggt tttgctcagt
     1441 aacatcgaat gtcgatgttc tgtattgtga accatggcaa catggacacc ggaagtgaat
     1501 tttattagta atatcagttg ccttaaagcg ccacaacgtt gaccgctgat ggaccttttg
     1561 gtccctgctc tgctgaaaac tccacttcct gattttcatt cagagtgcgg aattcattac
     1621 tttgaatggc ggaaaaatgc acaaacacat ctttgctgcc atctttaggc gtaatgaaac
     1681 caaagccctt ttcagggtta aaccatttta ctaaaccagt gattttcgtc gtcataatat
     1741 tgttaccttt tgaatgagcc cttgggcgaa atggcctgaa gaaaattatc agagagaaaa
     1801 aaacctaaag gagatctcaa gaggaacaaa tgatgagaaa tattacaatc actacttcag
     1861 ataagtttgt atcaaaccgc acaaccatta acgcatggtt aactgaacat agcaagcttt
     1921 agttttgtta aaaaaatatt aattgttttt tagcattatc acgctgattg ccatactctt
     1981 tttatccatg cccatcgcta cggctgaaac caggcgtaaa taagttacgt ctcacaacgc
     2041 ctgcctggca ataaacgcgc cacatttcct gatgtcgtaa accaggatac atgcgcatta
     2101 tcgtgagagg ttcctgtgat cttgtgcgac caaaagaacg gggacgattt agcaactatc
     2161 tcaggcattg atcgcacaag ttacttaaca cgcagtagat cagagtatct tgtggtgtac
     2221 cgaggcgaaa gcatttctcg cttcatagcc cactgttgcg acatcccctg cccggcgaag
     2281 tacagcgtcc ccttcccgtc ttttgcgtta agatggtcca gtacttccat caacttcgca
     2341 ctaccggcgc gcggcgcgtt atcgtcgaaa aggttgagtt gcgctacgcc ctggctgaag
     2401 aagccaccca gcatcacccc cgctttctgg tagcgatggc cgtcgcgcca gattttatcc
     2461 agacatttca cagccgcatt gataatgtca cgtgaatcct gcgtgggggt gagaagcgtc
     2521 accgcggcgc tgttaccgta gtagggctcg ttcagggcaa agggtgatgt tttgacgaat
     2581 gttgaaatga aacagcagta ctggtgctcg ccgcggagtt tttctgccgc gcgcgcagcg
     2641 tagctgtaaa cagcctggcg catttcctca tagtctgtga cccgctcgcc gaaagagcgg
     2701 ctacaaacga tttcctgctt tgccggcgca aactcttcaa gctccagaca tggctctccg
     2761 cgaagctctc tcacggtacg ctccagcacg acattgaagt gtttcctgat gatccaggta
     2821 ctttgttcag agagatcgag agcagtcttg atgcccaggg cattgagctt cttactgatg
     2881 cgtctgccga caccccagac atcctctacg ggtatcaggg ccagcagccg acgctggcga
     2941 tcgatgttcg acaggtcaac caccccgtcg gtctggcgct gccacttttt cgcagcatgg
     3001 ttagccagct tggcaagggt tttcgtctgg gcaatgccta caccgacagt caggtgcgtg
     3061 cgcttcagga ccgtcgctct tatctcgtgc ccgaaatctg tcagatcccg gcagtttcgt
     3121 acccccgtca gatcacaaaa agcctcatca atgctgtaaa tttctacccg cggcaccatc
     3181 tcctctagtg tggtcattac ctggttcgac atatcagcgt aaagctcgta attactgctg
     3241 aagcaaacaa caccggatcg ccggaagcgt tctttctgtt tgaagtatgg ctcacctgct
     3301 gcgataccga gttgtttcgc ctcggcgcta cacgcgataa cgcagccatc attgtttgat
     3361 aacaccacca ccggtcggcc acataaatca ggacgaaaga ccgtttcgca ggaggcgtaa
     3421 aagctattaa catcgcagag cgcgaacata atcaactgac cgctttaatg ataaaggtca
     3481 ccaccccgaa tatgtcgagc gtgtcttcac tgccgacagg tatgggtcga taggcgccgt
     3541 tcatggggat taactgcact gtcggacgca actgcaaccg ctttacggtg aactctcctt
     3601 caattgccgc aattacaatg tcaccgtggt cagcgttccg tgagctatcc accaccagca
     3661 ggtcaccgtc gctgatgcct gcttcaatca ttgaatcccc cgttgctttg acaaaatatg
     3721 ttgagctggg atgagaaacg agcaactcat taagatcgat acgctgctca atatagtccg
     3781 ccgcggggct ggggaatcca cacggcacta agtaactgaa aaatgggaga ggaataattt
     3841 cgcgcaactc tgtaggtctg aaaaattcca taatccatac ctcgaatact gtttttatat
     3901 acagtagtgt tatttgaaca tgcgcgcaag ataccggagt cgctacgact gtttaaatct
     3961 tcgtcgcttc gtttgtaagt ttctctctca gttcaaatta tgcgttttgt aaattttccg
     4021 gttgtattgt catgtgtgca tatttaagcc agtctggagg ccagattttc tgtacagcgt
     4081 cgacagtccc gcagcgtaag ttatcgccac gcgccagcgc gtttccctga cagcaattaa
     4141 tcttctgccc ggcgcccatg tctacagggg aacatttcgg gcaacaggcc gggtgcgacg
     4201 attaccgagg acgacggcgt taagtcgccg caagtgacat cactgtgaat cccgatgggg
     4261 tacagcgaaa tagcggggca gaaaaccagg agttgactta tgatcgaaaa gtaaaaataa
     4321 caccatccct ggccccctct tctggcagaa aaagcataag atggcgatac gtttttcacg
     4381 taatattcta acagaatact ctaagtgtat tctaagtgtg agactgatcg ctgaaagaag
     4441 atgagctaag tgtttgaatt gtggcggaga gagggggatt tgaacccccg gtagagttgc
     4501 ccctactccg gttttcgaga ccggtccgtt cagccgctcc ggcatctctc cgtatattgc
     4561 aatgatgcca ggtaatttgg cattttaaca gaccctattc gggtaatttt gttcaagtga
     4621 cgagtttacg agcaaaacga tgattaagtg gccctggaaa gcacaagaaa taacccagaa
     4681 cgaagactgg ccgtgggatg atgcgctggc tatacctctt ctggtaaacc tcaccgcgca
     4741 agaacaggct cggcttattg cgctagccga acgttttttg cagcagaaaa gactggtagc
     4801 gctacaggga tttgagctcg actcgttaaa aagtgcacgt attgcgttaa ttttttgctt
     4861 accgatcctg gagctcggta ttgagtggct tgatggtttt catgaagtgc tcatttatcc
     4921 cgcgcccttt gtggtagatg atgaatggga agatgacata ggtctggtgc acagccagcg
     4981 tgtcgtacag tcggggcaaa gctggcaaca agggcccatc attctgaact ggctggatac
     5041 ccaggactcg ttcgatgctt cgggtttcaa cctcattatt catgaagttg cgcacaaact
     5101 ggatatgcgt aatggcgatc gcgccagcgg catccctttc atcccgttac gcgatgtggc
     5161 tggctgggaa cacgatctcc acgcggcaat gaataatatt caggatgaaa tcgatcttgt
     5221 tggcgaaagc gctgccagta tagatgccta tgccgccacc gaccctgcag aatgttttgc
     5281 cgtgttgtca gagtattttt tcagcgcgcc agaactgttt gctccacgtt tcccggcgct
     5341 atggcagcgt ttttgccagt tctatcgcca ggatccttct cagcgcttac gggtaagcgc
     5401 tgccgaaggc gactacggcg aggaatccga acattaattc ctcactttgt gggttaatta
     5461 accaattgaa ttggcgcgtt aattttactg ttgacacgtt atagccggcc cagtattcaa
     5521 cgcctcgttg aaacaattcc tctgtagttc agtcggtaga acggcggact gttaatccgt
     5581 atgtcactgg ttcgagtcca gtcagaggag ccagatttag gaaagcagac gttcactgac
     5641 gtctgctttc tgcatttata tcaactgatt atccccttct tcaagtttac tctcgtttac
     5701 taaaaaccac tcgaagccat acccttttgc tggtaaagct ggtttgccat aattctgcct
     5761 gtgatattga cggaaatctt ttcgcctgca ccagaaattt atctgccatt tccgctaccg
     5821 gcgtcagact gcctgtatca accattttca caaaatattt cacgtctaaa gttcattctg
     5881 ccccctgccc ttaatctcta cggcgttatg tctcagaatt atttgccaag tgcctgccaa
     5941 tttttcacgc ctcatcaggc gctggtacat agccattgcg gtaaggtcac agcatttgac
     6001 ttgtgcaatg acagacaaag ttgcgccatg ccggggcaaa gtaggaatta gatcaaaact
     6061 tcaacgcttt gttgtttttg tcagcaaaca aacgcgcaat cttatttccc cctttgacaa
     6121 gccgatcgca catcgttact atgcgccccg ttcacacgat tcctctgtag ttcagtcggt
     6181 agaacggcgg actgttaatc cgtatgtcac tggttcgagt ccagtcagag gagccaaatt
     6241 tctgttttca ggcgtactta taagtcccta tttaattagg tttcaataag ttagcgtgaa
     6301 aacctttacc gatgcgtatc tggttttacc tgcgcatccg gtgaaattgg tggtctgatt
     6361 tggggccatt tcagttcgat aatggcgtga ccaccctata tccctgtcca acgcgaaaat
     6421 cctcagtatc aagccttctg ataatccctt taagctgatc gattctcacg gtcggtatct
     6481 gcttgttaat ccgggcttgt gggtccaggc gctcaaggag cgtgaagtgc ggcgcaatgt
     6541 tttcgccttc cggcgcgttt cctgacgtag acgcgattat cggcgacaga tctccggcga
     6601 tggtgatgaa gccgcggcac aataaggcct tagcgggatg cagaatcacc tcccgctaag
     6661 gcttcattca accactttcc atatcacata aatatgcctc ttccgctcct gcccaacagc
     6721 aggcgacagc ccatttcgtt agcgaaacgg cggctcatta aacgtgcgta atttacgtga
     6781 gtgcaaacga tcaccttctg cgcgtagtaa atcaatagca cgaataccaa tttgcaaatg
     6841 ttctgaaata gccccctcat aaaaccggtt tgcctgcccg ggcagtttaa tttcaccgtg
     6901 taaaggtttg tcagaaacac aaagcagcgt gccgtaaggc acgcggaagc gatagccctg
     6961 ggctgcaatc gtcgcgctct ccatatcaat cgcgaccgca cggctaaggt tgaatcgcag
     7021 cgcagatgcg gaataacgaa gctcccagtt acggtcatcc gtggtgacga ccgttcccgt
     7081 gcgcagtcgc tgtttcacct cttcgccggg cattccgcta accgctttgg tagcgtcgta
     7141 cagcgcacgc tgtacttccg caatgcttgg aatcggaata tcaggcggca gaacagcatc
     7201 cagcacatga tcatcgcgta agtaggcatg ggccagcaca taatcaccaa tcgcctgact
     7261 ttctcgtaac cctccacagt gcccaatcat aagccagacg tcaggccgca gcacggccaa
     7321 atggtcgcaa atcgttttag catttgaagg gccgacaccg atatttacca gcgtaatccc
     7381 ctgcccatct gccgttacca ggtgccaggc aggcatctga tgcttcttcc aggccagatc
     7441 ggaaatagcc tcttccggcg cttccgtttc tgccgtgatc caaattccgc cggcacagga
     7501 aagcgcgata tagggactgt caggatcaag aatttggctg catccccagc gcacaaactc
     7561 atcgacatag cgggtgtagt tggtaaacaa aacgaagggc tgaaaatgtt caaccggcgt
     7621 accggtatag tgccgtaacc gggccaacga gaagtcaaca cgacgcgcgt cgaagtgcga
     7681 taacggatag aattcgccgg ggtggaacag accgtctgcc gtctcatcgc caatctgcgc
     7741 cagttctgtg gtaggaaaat ggcgcgttag cccggcgctc atagaacgat ccagcgtcag
     7801 agccgagcca tcgatcacat aaggatacgg gatctcatgg tgcgaggcct ctatcgcaat
     7861 atgcgcgcca taatcatggt aaacgaggtt aagctgttcc agaagataag cgcgaaatag
     7921 cgcaggccgc gtaacggtag tggtataaca gccgggatga gtaaagcgtc caaaagcgcg
     7981 tgttttaggc gggttcggtg tcgcgccatc ccagcttaca gacagcgaag gataaacaaa
     8041 cagtccgtta agcctggcat ggggatcggg cagcgtgccg ttatcaacat agtcagcgat
     8101 ggcttcacgg agcgcgttaa ccgactgctc gtacagctcc tccaggcgat ccagcgcctg
     8161 ctcgggtgtc aggtttgtgc ctttattttc catattattc tccttagcgt tcacaggtga
     8221 ggcacgtcat tcgatagtat gacagcaaag gaggaaacta aaggggttag cgtaagggcg
     8281 gcggcagtaa acatgaaccc tttaaaaaga aaagagaact atcttagcgc caccatcatc
     8341 gctcaaaaag aagggtactg gtacagccat ttgttaagtt cattacaatt agtcatataa
     8401 ccatttcccg gcttttgctg actcgatcag catgctgata gtgaaatctg ggacgggtac
     8461 aggctccgtt ttcttgaacg gatgccatga aaaagggtga ttaggaaaat aggtttctat
     8521 tctgaagtta cctcgctcga cattgagttt ctcgaagaat ttattcatga gatcttcggc
     8581 ttcaagttca tcaatgctca gatcagtatc aaggtcaatc tctggtgtta attccacttg
     8641 cttaatgttg aacagatatg tgccagcata aggccgtaca agctcgtaaa cttgctgttc
     8701 aatattgtct agcataactt atcattgccc cgagcaatgg tattgtagtc gcgtatagtg
     8761 cgatatgcta tttgtgacac atctgcggca aggataattt ccccgatcaa aggaatggaa
     8821 cgtccaacaa acggcgcaat gttacgaacc ataacacgtc tggctgtcca cggggtgtaa
     8881 ccgcctaacc atgtcggaag ggatattcca aagggaaatt ttgacttttt aaacactgca
     8941 cgtgcagtcc tggacgcgta tgatgtgcct ttagtcgctc cagcgggttt cgcccttgtc
     9001 caaagattat tacgacctga taccagagca acaacagccc cgaaatctgc aacaccaatc
     9061 ccaaactggc ttgcggtatt ctcacagaaa atcataa
//
LOCUS       DAJVKX010000161         8701 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.161, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000161 DAJVKX010000000
VERSION     DAJVKX010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8701
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.161"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            180..722
                     /locus_tag="OPY25_003991"
     CDS             180..722
                     /locus_tag="OPY25_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfA"
                     /protein_id="HCS0929464.1"
                     /translation="MKKPVLALMVSAIAFGGMLSTAQADTTTVTGGTVNFVGQVVDAA
                     CSVSADSVDQTVTLGQVRASKLTEAGMAANQKEDFTIKLEDCDTQTSQNAAVIFNGQQ
                     DANQPGSLANTAGAGSATNVALQLYGPDGQALNIGESSSTVTLNDGENVIPLSVDYIA
                     TGTATAGNVTATATFSMVYS"
     gene            823..1509
                     /gene="bcfB"
                     /locus_tag="OPY25_003992"
     CDS             823..1509
                     /gene="bcfB"
                     /locus_tag="OPY25_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis chaperone BcfB"
                     /protein_id="HCS0929465.1"
                     /translation="MKKNVPIFLRLLLLLSAAGLSFAVQAGGIALGATRVIYPQGSKQ
                     TSLPIINSSASNVFLIQSWVANADGSRSTDFIITPPLFVIQPKKENILRIMYVGPSLP
                     TDRESVFYLNSKVIPSVDKNKLTGNSLQIATQSVIKLFIRPKNLAEAPAHAPATLRCR
                     NERGQLTITNPSPYYVSMVELYSAGKKLPNTMVPPKGAITLPATPGQVSLRTVNDFGA
                     TTPARVCPAS"
     gene            1514..4135
                     /gene="bcfC"
                     /locus_tag="OPY25_003993"
                     /pseudo
     CDS             1514..4135
                     /gene="bcfC"
                     /locus_tag="OPY25_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459028.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher BcfC"
     gene            4136..5143
                     /locus_tag="OPY25_003994"
     CDS             4136..5143
                     /locus_tag="OPY25_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfD"
                     /protein_id="HCS0929466.1"
                     /translation="MKIPLLFALLAGSVVSQYAHADVCKNVNGVPSSINYDLTTTLTA
                     EQNQVGKTVQLEKSQEVNVQAVCPAGASTYSQTYRSYVSPYPVVETSGNWKYLKLDPD
                     YLEGGMRIEDSSAGDIYPPMNNVLMGYDENVKAGQPFYVRDSNLEFQLKIVKPFVGTV
                     NISPKTMFNVYVMTAAGDPLTDVVYSILYSGTVTVPQSCEINAGQTILVNFGALYSGN
                     FNHAGQKPEGVRAKKFSVPVKCSGLDSQVNLTMRLIATPDSHFPQAIASDNADVGVVV
                     ETDEGNALIPNDVQSVAPFITDSAGRANITLQAYPVSTTGETPAEGAFTALASLRVDF
                     D"
     gene            5144..5689
                     /locus_tag="OPY25_003995"
     CDS             5144..5689
                     /locus_tag="OPY25_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfE"
                     /protein_id="HCS0929467.1"
                     /translation="MNRSHCALFVMGLILCPQINASADDLAYNLEFTGTIVAQTCDID
                     ISSLSQSIDLGQFAVGDFPSTGTTTKFKPFNINLKNCSRGITGAKIWFTGEPDPDNPA
                     LLAITDTGMGSGNMLASGVGVEILNDDQDTISINNADSVVYPLKAGRNTLSFYIRYKS
                     TRPTVTSGNATAVMYFDMQYE"
     gene            5705..6223
                     /locus_tag="OPY25_003996"
     CDS             5705..6223
                     /locus_tag="OPY25_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfF"
                     /protein_id="HCS0929468.1"
                     /translation="MRNDILYGIGMLLAASGVQAHDGRVYVSGTITDNTCSLSPGSEN
                     INVAMGAVSQRQFYRAGDGSAWQPFAIDLQNCGSTASGVTVSFSGAGDSRNTDLLALT
                     AGESDASGIGIALYDQNKTLIPLGQESDVVTLSPGQASAHLQFYARYLADGGTVTPGD
                     ANASATFILAYE"
     gene            6189..6920
                     /gene="bcfG"
                     /locus_tag="OPY25_003997"
     CDS             6189..6920
                     /gene="bcfG"
                     /locus_tag="OPY25_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone BcfG"
                     /protein_id="HCS0929469.1"
                     /translation="MPPQPSFLPMNKFFLHCAIYWCLLPISWAQAGVVIGGTRFIYHA
                     GAPALSVPVSNHSEASWLIDTHILPGGRWPGTKNEGNITPFVVTPPLFMLSARQENSM
                     RVVYTGGPLPADRESLFTLSIAAIPSGKPEANRVQMAFRSALKLLYRPEGLAGNPQQA
                     YRHLIWSLTPDGATVRNPTPYYVTLFLLRANERAQDNAGVVAPFATRQTDWCRHAVRC
                     TVRWQSINDYGRVMTAQTVDLTRIH"
     gene            6985..7830
                     /locus_tag="OPY25_003998"
     CDS             6985..7830
                     /locus_tag="OPY25_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCS0929470.1"
                     /translation="MYYHALKLSRLAMLTLAGVAVSASAIAADSAPTSQIGPTAEAYI
                     VSHPDKVGEVVATYLAEHPEFLVAASETLHQRQQIAQQQAYVQLALQYRAELLSSSSP
                     SVGPSEAKAAVVMFFDYQCSWCSKMAPVVENLIKANPDTRFIFKEFPIFSSRWPVSGL
                     AARVGEQVWLTQGGAKYLDWHNALYATGKVEGALTEHDVYTLAQHYLTPTQLAAVKEA
                     QSSGAVHDALLTNQALAQHMDFSGTPAFVVMPQTQNGDVKRVTVIPGSTTQDMLQMAI
                     QKAKG"
     gene            7869..8156
                     /locus_tag="OPY25_003999"
     CDS             7869..8156
                     /locus_tag="OPY25_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929471.1"
                     /translation="MKSMRCVIPVILLSFIVHEGTAKPTAQIHFMGSVVEAGCWNDVG
                     TLEIQCYNKEGVERYIIVENIITPISSPHATVKRDYLDEDKQLTVLRIVYD"
     gene            complement(8256..>8701)
                     /locus_tag="OPY25_004000"
     CDS             complement(8256..>8701)
                     /locus_tag="OPY25_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCS0929472.1"
                     /translation="QYTINNEFIYNESLREIISLHDKKVLKVTLMRARCLSYLFENAY
                     KKLITREMISHAVWGERSQFVSDANLTQLLYLLRRDLQQIGLFELFVTLPRQGIKIDE
                     RFIIDAADIPPQAIQYHTHRCNKIISIGIPTLFLLIVLFFLAPFI"
BASE COUNT         2150 a         2131 c         2323 g         2097 t
ORIGIN      
        1 taacgtaaag attaactcac gacgttgagt agctgtttta ttgcctctga catttatatc
       61 agaacaagaa gacacttttt tcgcataaga aaagtcgtga tattgctgtg aagaaatatc
      121 agcagccgtt tcgttaaaaa atctgattac cctcattttt atatttaaaa ggagcttgaa
      181 tgaaaaagcc tgtactagca ttaatggtct ctgccattgc ctttggcgga atgttgtcca
      241 ccgcgcaagc ggatactaca accgtcactg gcggtacggt aaattttgtc ggacaggtcg
      301 ttgacgccgc ctgttctgtt tccgctgact ctgtcgatca gaccgtgaca ttaggccagg
      361 ttcgcgccag taaattaacc gaggccggta tggcggcgaa tcaaaaagaa gatttcacca
      421 ttaaactgga agactgcgat actcagacca gccagaatgc ggcggtgatt tttaatggcc
      481 agcaggacgc aaaccagccg ggttcgctgg cgaataccgc tggggcaggt tcggcgacga
      541 atgtggcact acaactttat ggaccggatg gccaggcgct gaatattggt gaatcgtcca
      601 gtactgttac cttgaacgat ggcgaaaacg ttattccgct tagcgtggat tatatcgcta
      661 ccggtacggc gactgccggt aatgttaccg cgacggcgac atttagcatg gtttattcct
      721 gattccttat cgggattttt ttctcgtctg ttgggaggcg agaaaggggc gttacgcgcg
      781 tcactgcgcg taacaaaccg acggcatcag gatattacgc agatgaaaaa aaacgtaccg
      841 attttccttc gattattgct actgctgtcg gcggccggcc tgtcgtttgc cgtgcaggcg
      901 ggaggcattg cgctgggcgc gaccagggtg atttatccgc agggaagtaa gcaaacctcc
      961 ttgccgatta ttaattcttc tgccagcaat gtttttttaa ttcagtcgtg ggtcgccaat
     1021 gccgatggtt cacgctcgac ggattttatc attacgccgc ctctctttgt gatccagcct
     1081 aaaaaagaaa atatattacg tattatgtat gtcgggccgt cattaccgac cgatcgcgaa
     1141 agcgtgtttt atttaaacag taaagtgata ccctctgtcg ataaaaataa actgaccggc
     1201 aactccctgc aaattgcgac gcaaagcgtg attaagctat ttatccgccc gaaaaatctg
     1261 gcggaggcgc cagcccatgc cccggcaacg cttcgctgcc gtaacgagcg cggccagcta
     1321 acgattacta acccttcgcc gtactacgtt tcgatggttg aactgtacag cgcggggaaa
     1381 aaactgccga atactatggt accgccgaaa ggcgcgatca ctctcccggc gacgcctggc
     1441 caggtatctt tgcgcacggt aaacgatttt ggcgcaacga cgccagcacg cgtttgtcca
     1501 gcttcatgat gttatgcgta atcagctttt catgacgcga tattactcca gcgtagctaa
     1561 acccgtatta actccgctgg cgttggctat cgcactggcg cctgcgcctg ggtgggcgga
     1621 aaactatttc aacccggcat ttctgtctga cgacccgtct gcggtggccg acttatcgac
     1681 cttttcccgt aatgcccagg cggcgggaat gtatcgcgtt gacgtttacc tgaacaatac
     1741 gtttctcgcg accagagaca ttgccttcca ggcggtgaag acgacgggaa aaagcgcgcc
     1801 caccgatgac agcggattac gcgcctgcct gacgcctgaa atgcttaaaa atatgggggt
     1861 aaacaccggg gcatttccac tgttggcgaa ggcggcggcg ggaagttgtc cggatctcgc
     1921 cagtgcgata ccggccgccc ggacccgctt tgattttgcg cagcaacgtc tcgacattag
     1981 catcccgcag gcggcgatgg ttgccagcgc cagaggctat atcccaccgc aatactggga
     2041 tgaaggtatt aacgcgttgc tattgaatta cacctttacc ggcgcgaata gtcaggatcg
     2101 gagcccaggc ggcagtgcgg agaacagcta ttttcttgga ttgaatagcg gccttaatct
     2161 gggggcctgg cggttacgcg actactccac atggaacgcg aatagcggcg atcagaatag
     2221 cgacagcgac tggcagcaca tcagtactta tctggaacgt gatgtggtct ttttgcaggg
     2281 agaactgacg gcaggcgata gttatacccc ctccgcatta ttcgatagcc ttccttttcg
     2341 cgggctacaa ctggcgtctg acgacaatat gttgccagac agcatgaagg gcttcgcgcc
     2401 gaccattcac ggcattgcca gaagcaacgt gtaagtgacc attcggcaaa acggctacat
     2461 catcaatcag cgctatgtgc cgcccggggc atttactatt aatgatctct atcctaccgc
     2521 cgccagcggc gatttgactg tggaagtcaa agagtccgac ggttctatta atcgctataa
     2581 cgtgccctat tccgccgtgc cgattctaca acgagaaggg cggctgaagt atgcggcgac
     2641 ggtggcggag tatcgtagcg atagtagtca aaaagagaag gtgaaattca gtcaggcgac
     2701 cttgatatgg gggttaccgc atggttttac gctgtatggc ggaacacaac tttccagtca
     2761 ttatcacgcg ctggcgatcg gcagcggcgc aaatctgggc gactggggcg cggtgtcgct
     2821 ggatgtcacc caggctacca gtacgctggc ggataataac tcctaccagg ggcaatcgct
     2881 gcgtttcctg tatgccaaat cgcttgcaca gtcaggaacc aatttacagc ttatgggcta
     2941 tcgctattca acctcgggct tttacacgtt ggatgatacc acgtggaaac ggatgagcgg
     3001 ctatgacgat gacaatcgga ctgacagcga taaaagcagg ccggaatggg cggattatta
     3061 caatctttat tataccagga ggggcaaagt acaactcgat atcaatcaac agctaggcgg
     3121 gttgggatcg ctttttatta ccggcagtca gcaaagttac tggcacactg atgaaaagga
     3181 ttctttgttg caggtgggat acagcgatac gctggcgggt attgcatgga gcgtttctta
     3241 caacaataac aaatccgcag gcgatgcgga gcgcgatcaa attttcgccc tgaatatctc
     3301 ggtgccgcta agtcaatggc tgcaacatga tgatgaggtc acgcaccatc acaatgttta
     3361 cgctaccttt agcaccagta cggacaaaca gcataacgtt acgcagaatg cgggccttag
     3421 cggcacacta ctggacgaaa acaatcttag ttacaacata cagtaaggct atcagaatca
     3481 cggtattggc gaaagcggcg ccgccagcct ggaatacgat ggggcgaaag gcaacgccaa
     3541 tattggctat aacgttagcg ataacggcga ttaccagcag gtgaattatg gcctgagcgg
     3601 cggcctggtg gcgcacgcgc atggagtgac gctaagccag ccgttaggca ataccaatat
     3661 tttgattgcc gcgccgggcg cagccaatgt cggcgttgtc gaccagccgg gtattcatac
     3721 ggacgcgcgt ggctatgcgg tggtgccgta tgcgacgaca tatcgccaaa accgtatggc
     3781 gctggacgtt aacgccatgg ctgatgatgt cgatattgat gacgcggtga ctcgcgttgt
     3841 gccgaccgaa ggcgcgctgg ttctggcccg ctttaaagcg cgagtcggcg tgcgtgccct
     3901 ggtaacgctg aatcataatg gtaagcctgt accctttggc gcaacggtga cggtgaatga
     3961 tcgccatgcg gaggcgattg ttgacgaggc cggggaggtc tatctttccg ggttgtcagc
     4021 gcaaggcgtt ctgcacgttc gctgggggaa cctgccggat caacagtgcg tcgcgtccta
     4081 tcatctctct tcctcccgtc agattctgag tcgacaatat gcggagtgtc attaaatgaa
     4141 aatacctctt ttatttgctc tgctggcggg gagtgtcgta tcgcagtacg cacacgcaga
     4201 cgtgtgtaaa aacgttaacg gcgtgccttc cagtattaat tacgatttaa cgaccactct
     4261 gacggcagaa caaaaccagg tgggaaagac ggttcaactg gaaaaaagcc aggaagttaa
     4321 tgtacaggcg gtgtgtcccg ccggcgcgtc gacctatagc cagacttatc gctcctatgt
     4381 gtcgccatat ccggtcgtag aaacgagcgg taactggaaa tatttaaagc tggacccgga
     4441 ctaccttgaa ggcggaatgc gaattgagga ttcttcggcg ggcgatatct atccgccaat
     4501 gaacaatgtc ctgatgggat atgatgaaaa tgtgaaagcg ggtcaaccgt tttacgttcg
     4561 tgactcaaat ctggagtttc agctcaaaat tgttaaaccg ttcgtcggca cggtgaatat
     4621 tagtcctaag actatgttca atgtttatgt catgaccgcc gcaggcgatc cgctgacaga
     4681 tgtcgtgtac agcattcttt atagtggaac ggtgaccgta ccgcaaagct gcgaaatcaa
     4741 cgccggacaa acgattctgg tgaatttcgg tgcattatac agcggcaatt tcaaccatgc
     4801 aggccaaaag ccggaggggg tacgagcgaa aaaattcagc gtaccggtaa agtgcagcgg
     4861 tctggattcg caggtcaatt taacgatgcg tcttatcgct acgccggata gccactttcc
     4921 ccaggctatc gcttcggata atgccgatgt cggtgtagtg gtcgaaaccg atgaaggaaa
     4981 cgcgcttatt cccaatgatg tacagagcgt cgcgcctttt atcaccgata gcgccggacg
     5041 cgctaacatc acattgcaag cctacccggt gagtacaaca ggtgaaacgc cagcggaagg
     5101 ggcgtttacc gccctggcca gcctgcgagt ggactttgac taaatgaaca gatcacactg
     5161 cgctcttttt gtcatgggac taatcctgtg tccacaaatc aatgccagcg ctgacgacct
     5221 cgcttataac ctcgaattta ccggcactat tgtggcgcaa acttgcgaca tagatatttc
     5281 cagtctcagt caaagtattg atttagggca gtttgcagtt ggcgattttc cttcgacagg
     5341 aacaacgaca aaatttaagc cctttaatat caacctcaaa aattgttccc gaggaattac
     5401 cggggcgaag atctggttta ccggcgaacc cgatccggac aatcccgcgc tactggcaat
     5461 aaccgatacc ggaatgggaa gcggaaacat gttagcaagc ggggtagggg tggaaattct
     5521 gaatgatgat caggatacca tcagtatcaa taatgccgac tcagtggtct atccgttgaa
     5581 agccggacgc aacacgctgt ctttttatat tcgctataaa tcgacccggc cgacggtcac
     5641 gtccgggaac gcgacggcgg tcatgtattt cgatatgcag tatgaatgag gagccatcgt
     5701 aattatgcgt aacgatatcc tgtacggcat cgggatgctg ctggcggcat ccggcgtcca
     5761 ggcgcacgat ggccgggtct atgtctccgg aaccatcacg gacaatacgt gttcgctctc
     5821 tccaggctcg gaaaatatta acgtggcgat gggcgcggtt tctcaacggc agttttatcg
     5881 cgcgggcgac ggttccgcct ggcaaccttt tgctatcgat ttacagaact gcggtagcac
     5941 tgccagcggc gtaacggtca gttttagcgg tgcaggggat agccgtaata cggatttatt
     6001 ggcgcttacc gcaggggaaa gcgacgcttc aggaattggg attgcgcttt atgatcaaaa
     6061 taaaacttta atcccactgg ggcaggagag tgatgtggtg acgctcagtc cgggccaggc
     6121 gtcggcgcat ctgcaatttt acgcgcgtta tcttgccgat ggcggcacgg taacgcccgg
     6181 ggacgccaat gcctccgcaa ccttcattct tgcctatgaa taagttcttt ttacactgcg
     6241 cgatatattg gtgcttgctt cccatatcat gggcgcaggc tggcgtggta attggcggta
     6301 ctcgctttat ctatcatgcg ggcgccccgg cattaagcgt accggtaagt aaccattcag
     6361 aagcgtcctg gttaattgat acgcatattt tacctggtgg ccgctggcct ggaaccaaaa
     6421 acgaagggaa tattacgccc ttcgtggtca cgccgccatt atttatgctt tcagcgcgcc
     6481 aggaaaactc aatgcgggtg gtttataccg gcggaccgct acccgccgac agggaaagtc
     6541 tgtttacctt gagtatcgcc gctattccct ccggtaaacc ggaagcgaac cgtgtacaaa
     6601 tggcgtttcg ttcggcttta aaattgctct atcgccctga gggactcgcc ggcaatccgc
     6661 agcaggccta ccggcatctg atctggtcgc ttacccccga tggcgcgacg gtacgcaatc
     6721 cgacacccta ttacgttacg ctctttttat tacgcgctaa cgagcgcgcc caggacaacg
     6781 ccggggtcgt ggctcccttt gcaacgcgtc aaacggactg gtgccggcac gcggttcgct
     6841 gcactgtgcg ctggcaaagt attaatgact atgggcgggt aatgacagcg caaaccgtgg
     6901 atctgacgcg tattcattaa cctatttttc aggcgtctcc cgatagcggg aggctttccg
     6961 atcttatcga acgagacttt tattatgtat tatcacgcgt taaaactttc ccgactggcg
     7021 atgttgacgt tggcaggcgt tgcagtatcc gcctcggcaa tcgccgccga ttctgccccg
     7081 acgtcgcaaa ttggcccgac ggcggaagcc tacatcgtca gtcatccgga taaagtggga
     7141 gaggtggtgg caacgtattt ggccgaacat ccggaatttt tggtcgccgc cagcgagacg
     7201 ttacatcagc gtcagcagat tgcgcaacaa caggcgtatg ttcaactggc attacagtat
     7261 cgtgctgagt tgctcagtag cagcagtcct tccgttgggc ccagcgaggc aaaagcggcg
     7321 gtggtaatgt tctttgatta ccagtgctcg tggtgcagca aaatggcgcc tgtggtcgaa
     7381 aacctgatta aggcgaaccc ggatactcgg tttattttca aagagtttcc tattttttcc
     7441 tcccgctggc cggtatccgg actggcggca agagtcggcg aacaggtatg gcttacacag
     7501 ggcggggcga aatatctcga ctggcataat gcgctttatg ccacagggaa ggtggaaggc
     7561 gcgttaacgg aacacgatgt ctacaccctg gcgcaacatt atctaacgcc gacgcagctg
     7621 gccgccgtaa aagaagcgca aagcagcggt gcagtacatg atgcgctcct cactaaccag
     7681 gcactggcgc agcatatgga ctttagcggc acgcctgctt ttgtcgtcat gcctcagacg
     7741 caaaacggtg atgtaaaacg ggtgaccgtg atcccgggaa gcacgactca ggatatgttg
     7801 caaatggcga ttcagaaagc gaaggggtga tattcgctca gaggagaacg cacaggagtg
     7861 aaagtaaaat gaagtctatg cgttgcgtca taccggtgat tttactttcc tttatcgttc
     7921 atgaagggac agcgaaaccg accgctcaga ttcattttat gggatcggtt gttgaggcag
     7981 gctgctggaa tgacgtggga accttagaaa ttcaatgcta taataaagag ggagttgaac
     8041 gttatattat tgtcgagaat attatcacgc cgatatcgtc tcctcatgca acggtaaaac
     8101 gagattattt ggatgaagat aagcaattaa cagtgctacg cattgtctat gactgaaccg
     8161 cgtagcagac cgcaggtggt gtcccgtcag tgtcgtgtga ggatattatg aaaaatgttc
     8221 tcaccttccc gggacacggt ctacagactt tatcttcaga taaacggcgc taaaaagaaa
     8281 agtacgatca ataaaaaaag agtgggaata ccaatagata taattttatt acatcggtga
     8341 gtatgatatt gaatagcttg tggcggtatg tcagcagcgt caatgataaa tctttcatcg
     8401 atttttatcc cctgcctggg gagcgtaacg aacagttcga aaagcccgat ttgttgtaaa
     8461 tctcgtcgca gcagataaag aagttgcgtc aaattagcat cgctaacaaa ttgacttcgc
     8521 tctccccaaa ctgcgtgtga aatcatctcc cgcgtaatca gtttcttgta ggcattttca
     8581 aaaagatagc ttaaacaacg cgcacgcatt agcgtcacct ttagcacttt tttatcatgt
     8641 aatgatatta tttctcttaa cgactcatta taaataaatt cgttattaat agtatattgt
     8701 c
//
LOCUS       DAJVKX010000162         8611 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.162, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000162 DAJVKX010000000
VERSION     DAJVKX010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8611
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.162"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..110)
                     /locus_tag="OPY25_004001"
     CDS             complement(<1..110)
                     /locus_tag="OPY25_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5066 family protein"
                     /protein_id="HCS0929473.1"
                     /translation="MDISLTNLMELVKKVNRNKVPNPMPAEEISCLRVRK"
     gene            complement(357..1199)
                     /gene="sseA"
                     /locus_tag="OPY25_004002"
     CDS             complement(357..1199)
                     /gene="sseA"
                     /locus_tag="OPY25_004002"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HCS0929474.1"
                     /translation="MTTAFFVAADWLAEHIDDPEIQILDARMAPPGQEHRDMAGEYRA
                     GHIPGALFFDIEALSDRASPLPHMMPRPEAFAVAMRELGVRQDKHLVIYDEGNLFSAP
                     RAWWMLRTFGAEKVSILAGGLAGWQRDEWLLREGEEAHEGGEFEAKFTPQAVVRLTDV
                     LLASHEKTAQIVDARPAARFNAQADEPRPGLRRGHIPGALNVPWTELVYEGELKTTDE
                     LNEVFFSHGVSFDRPIIASCGSGVTAAVVVLALATLDVPDVTLYDGAWSEWGARTDLP
                     VEPA"
     gene            1408..6342
                     /locus_tag="OPY25_004003"
     CDS             1408..6342
                     /locus_tag="OPY25_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HCS0929475.1"
                     /translation="MKHLRVVACMIMLALAGCDNNDKTAPTTKSEAPAVAQPSPAQDP
                     SQLQKLAQQSQGKALTLLDASEAQLDGAATLVLTFSIPLDPEQDFSRVVHVVDKKSGS
                     VDGAWELAPNLKELRLRHLEPERVLVVTVDPAVKALNNATFGKSYEKTITTRDVQPSV
                     GFASRGSLLPGKIAEGLPVMALNVNHVDVNFFRVKPGSLASFVSQWEYRSSLSNWESD
                     NLLKMADLVYTGRFDLNPARNTREKLLLPLSDIKPLQQAGVYVAVMNQAGHYNYSNAA
                     TLFTLSDIGVSAHRYHSRLDIFTQSLENGAAQSGIEIVLLNDKGQTLAQATSDAQGHV
                     QLEADKAAALLLARKEGQTTLLDLTLPALDLSEFNVAGAPGYSKQFFMFGPRDLYRPG
                     ETVILNGLLRDSDGKTLPDQPVKLEVVKPDGQVMRTVVSQPENGLYRLNYPLDINAPT
                     GLWHVRANTGDNLLRSWDFHVEDFMPERMALNLTAQKTPLAPADEVKFSVVGYYLYGA
                     PANGNTLQGQLFLRPLRDAVAALPGFQFGNIAEENLSRSLDEVQLTLDKGGRGEVSAA
                     SQWQEAHSPLQVILQASLLESGGRPVTRRVEQAIWPADTLPGIRPQFAAKAVYDYRTD
                     TTVNQPIVDEDSNAAFDIVYANAQGEKKAVSGLQVRLIRERRDYYWNWSESEGWQSQF
                     DQKDLVEGEQTLDLNADETGKVSFPVEWGAYRLEVKAPNETVSSVRFWAGYSWQDNSD
                     GSGAARPDRVTLKLDKANYRPGDTMKLHIAAPVAGKGYAMVESSDGPLWWQAIDVPAQ
                     GLELTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGLLHLPLGDDNRRLDLALE
                     SPAKMRPNQPLTVRVKASVKHGEMPKQINVLVSAVDSGVLNITDYATPDPWQAFFGQK
                     RYGADIYDIYGQVIEGQGRLAALRFGGDGDDLTRGGKPPVNHANIIAQQAQPITLNEQ
                     GEGVVTLPIGDFNGELRVMAQAWTADDFGRGESKVVVAAPVIAELNMPRFLAGGDVSR
                     LVLDVTNLTDRPQTLNIALAASGLLELLSQQPQPVNLAPGVRTTLFVPVRALEGFGEG
                     EIQATISGLNLPGETLGAQHKQWQIGVRPAWPAQTVNSGIALAPGESWHVPEQHLANV
                     SPATLQGQLLLSGKPPLNLARYIRELKAYPYGCLEQTTSGLFPALYTNAAQLQSLGIT
                     GDSDEKRRAAVDIGISRILQMQRDNGGFALWDENGAEEPWLTAYAMDFLIRAGEQGYS
                     VPPEAINRGNERLLRYLQDPGTMLIRYSDNTQASTFAAQAYAALVLARQQKAPLGALR
                     EIWERRSQAASGLPLMQLGIALNTMGDARRGEEAITLALNTPRQDERQWIADYGSSLR
                     DNALMLSLLEENNLRPDAQNALLSSLSEQAFGQRWLSTQENNALFLAAHSRQASAGAW
                     QAQTSLEAQPLSGDKALTRNLDADQLAALEVTNTGSQPLWLRLDSSGYPSSAPEPASN
                     VLQIERQILGTDGQRKSLSSLRSGELVLVWLTVVADRNVPDALVVDLLPAGLELENQN
                     LADSSASLPESGSEVQNLLNQMQQADIQYMEFRDDRFVAAVVVNEGQPVTLVYLARAV
                     TPGTYQLAQPQVESMYAPQWRATGASEGLLIVTP"
     gene            6343..>8611
                     /gene="pbpC"
                     /locus_tag="OPY25_004004"
     CDS             6343..>8611
                     /gene="pbpC"
                     /locus_tag="OPY25_004004"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461466.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HCS0929476.1"
                     /translation="MNGWRGKRGRWLWLAGAPLFIFLALWAADKLWPLPLNEVHPARV
                     VVAHDGTPLWRFADAGGIWRYPVTIEEVSPRYLEALINYEDRWFWQHPGVNPFSVARA
                     AWQDLTAGRVISGGSTLTMQVARLLDPHSRTFGGKIRQLWRALQLEWHLSKRDILTLY
                     LNRAPFGGTLQGIGAASWAYFGKPPARLSYADAALLAVLPQAPSRLRPDRWPTRAEAA
                     RNKVLDRMAEQGVWPAETVRESREEPVWLAPRQMPQLAPLFARMMLSKSRSDKIVTTL
                     DAGLQRQLEDLARAWKGRLPARSSLAMIVVDHTDMSVRGWVGSVDLNDDSRFGHVDMV
                     TAIRSPGSVLKPFVYGLALDDGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSDA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPAGAAPNLSLILGGAGARLDEMAA
                     AYSAFARHGKAAKLRLQPDDPLSERPLMSPGAAWIIRRIMADEAQPLPDNALPRIVPL
                     AWKTGTSYGYRDAWAIGVNARYIIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNLLLA
                     HTGRLPEDPRPQTVSRGVICWPGGQTLPAGNSNCRRRLATWLLDDSQPPTLLLPEQED
                     INGIRFPVWLDDTGRRVAADCPQARAHTFIVWPRPLEPWLPPAERRSARLPAASDHCP
                     PLQGNDAAPLMLSGVRDGAVIRQLPGQENVTLPVSTTGGKGRRWWFLNGEPVNGENNR
                     LSLLLNIAGRYQLVVM"
BASE COUNT         1830 a         2392 c         2629 g         1760 t
ORIGIN      
        1 tacttacgca ctcgcagaca acttatttcc tcggcaggca taggattagg caccttattg
       61 cggttaacct ttttaactag ctccattaaa ttagtgagtg aaatatccat tttccatcct
      121 taaaaaatta tatttacagg agttatttcc cggtgaaacc caaaacagcg gtgatgatac
      181 tccttatacc cgacgtaaag tatttaccga taaaaaatag gattttatta agagaaaata
      241 atgcccgttt gcaggacagt ggaaaagagc ggaataaaaa caatgtctgt agatcgtttt
      301 acatcagcct gaacggtagg ccggataagc gtgagcacca tccggcatgg cggatattaa
      361 gcgggttcaa ccggtaaatc ggtacgcgcg ccccattcgc tccacgcgcc gtcgtaaagc
      421 gtgacgtcag gcacatccag cgtggcgagt gccagcacca cgaccgcggc cgtcacgccg
      481 gaaccgcaac tggcgataat cggtctgtcg aaactcacgc cgtggctgaa aaaaacctca
      541 ttcagttcgt cagtggtctt taattcgccc tcatacacca gttccgtcca cgggacgttt
      601 agcgcgccag gaatgtgtcc gcgtctcagt cccggacgcg gttcatcagc ctgagcgtta
      661 aaacgcgccg ccggacgcgc gtcgacgatt tgcgcggttt tttcatggct tgccagcaat
      721 acgtcggtga gacgcaccac ggcttgcggc gtgaatttcg cctcaaactc gcctccttca
      781 tgcgcttctt cgccttcgcg caatagccat tcgtcgcgct gccagcccgc cagtccgccc
      841 gccagaatgg acactttctc ggcaccgaac gtgcgcagca tccaccatgc tcgcggagcg
      901 gagaacagat tgccttcatc gtatatgacc aggtgtttat cctggcgaac acccagttca
      961 cgcatggcca ccgcaaacgc ttccgggcgc ggcatcatat gcggcagcgg cgatgcgcga
     1021 tcggaaagcg cttcaatatc aaaaaacagc gcgccgggaa tatgtccggc gcgatattcg
     1081 cccgccatat cacgatgttc ctgtcctggt ggcgccatac gggcgtcaag aatctgtatt
     1141 tccggatcat caatatgttc ggcaagccag tcggcggcga caaaaaaggc ggtggtcatg
     1201 ggcatctcca ttgttacctg attatggtca aattgtcgga cgtttcccga aaagggacaa
     1261 gtagaagagg ctgttttggc tggcgaaacc acatttctgc gtaaaatttt cgcgtcatca
     1321 cagtaatacg gacttacaca ataaaatttc tcgcgcataa tatctcatca accgttgctg
     1381 acaggccgtt aaggccaggg atgaaagatg aaacatttac gcgtggtggc ctgcatgatc
     1441 atgctggcgc tggcgggatg cgataacaac gataaaaccg ccccgacgac taaaagcgaa
     1501 gcgccagccg tagcgcagcc ctcgcccgcg caagacccgt cacagctaca aaagctggcg
     1561 cagcaaagcc agggcaaagc gctcacgcta ttagacgcct ccgaagcgca gctcgacggc
     1621 gcggcgacgc tggtgctgac gttttcaatt cctttagatc ctgaacagga tttctcccgt
     1681 gtggttcacg tggttgataa gaaaagcggc agcgttgacg gcgcatggga gctggcgcca
     1741 aatttaaaag agctaaggtt acgtcatctg gaacctgagc gcgtgctggt ggtcacggtt
     1801 gatcccgccg ttaaagcgct gaataacgcc accttcggca agtcttatga aaaaacgatt
     1861 accacgcgtg atgtccagcc cagcgtcggc tttgccagcc ggggatcgct gctaccgggg
     1921 aaaatagcgg aaggactgcc ggtcatggcg cttaacgtca accacgttga tgtgaacttt
     1981 ttccgcgtta agcccggatc gctggcgtcg tttgtcagcc agtgggagta ccgtagttcc
     2041 ctctctaact gggaatccga caatctgctg aaaatggcgg atctggttta taccggtcgt
     2101 tttgatctta atccggcgcg taatacgcgt gagaaactgc tgctgccatt aagcgatatt
     2161 aagccgctgc aacaggcggg cgtatatgtg gcggtaatga atcaggctgg acactacaac
     2221 tatagtaatg ccgctacgtt gtttaccctt agcgatatcg gcgtgtccgc gcaccgttac
     2281 catagtcggc tggatatctt tacgcaaagc ctggaaaacg gcgcggcgca gtcgggaatt
     2341 gagatcgttc ttctgaatga taaagggcag acgctggcgc aggcgacgag cgacgcgcag
     2401 ggacatgtgc aactggaggc tgataaagcg gcggcgctat tactggcgcg taaagagggg
     2461 cagaccacgc tgctcgatct cacgcttccg gctctggatc tgtcggagtt taatgtcgct
     2521 ggcgcgcccg gctacagcaa gcagttcttt atgttcggcc cacgcgatct ctaccgaccg
     2581 ggcgaaacgg ttatcctcaa cggattactg cgcgatagcg acggtaaaac gctgcccgat
     2641 caacccgtta agctggaagt ggtaaaacca gacggacaag tgatgcgtac cgtcgtcagc
     2701 cagccggaaa acggactata ccgtttgaat tatccgctgg atatcaacgc gccgaccggc
     2761 ttgtggcatg tccgcgccaa caccggcgat aatttgctgc ggagttggga tttccacgtg
     2821 gaagacttta tgccggagcg gatggcgctc aacctgacgg cgcaaaaaac accgctggcg
     2881 cctgcggatg aggtgaaatt ctccgttgtc ggctattact tgtatggcgc ccctgctaac
     2941 ggcaataccc tgcaagggca acttttcctg cgtccgctgc gcgacgctgt cgcggcgttg
     3001 cctggcttcc agttcggcaa tattgccgaa gagaatcttt cgcgcagcct ggacgaagtt
     3061 caactgacgt tggataaagg cggacgtggt gaagtgagtg ctgccagcca gtggcaagaa
     3121 gcgcattcgc cgttgcaggt aattctacag gccagcctgc tggagtctgg cggtcgtccg
     3181 gtcactcgtc gcgtagagca ggcgatttgg cctgccgata cgttaccggg aattcgtcca
     3241 cagttcgccg ccaaagcggt atacgactac cgtacggata ccaccgttaa tcaaccgatt
     3301 gtcgacgaag acagcaacgc cgcattcgat attgtttacg ccaacgcgca gggcgagaaa
     3361 aaagcggtgt ccggtttaca ggtgcggctc atccgcgagc gtcgcgacta ttactggaac
     3421 tggtcggaaa gcgaaggctg gcagtcgcag tttgatcaaa aagatctggt ggagggcgag
     3481 cagacgctgg atctgaacgc ggatgaaacc ggaaaagtca gcttcccggt ggaatggggc
     3541 gcgtaccgtc tggaggtcaa agcgccgaat gagacggtca gcagcgttcg tttctgggcc
     3601 ggctatagct ggcaggataa cagcgacggt agcggcgcgg cgcgtccgga tcgcgtcacc
     3661 ctcaaactgg ataaagcgaa ttatcgtcca ggcgacacca tgaaattgca tatcgccgcg
     3721 ccggtcgccg gtaaaggtta tgccatggtg gagtccagcg atggtccgct gtggtggcag
     3781 gcgatcgacg tgccggcgca ggggctggag ctcacgattc cggtggataa aacctggaat
     3841 cgccacgatc tctatctcag tacgctggtg gtgcgtcccg gcgataaatc tcgttccgcg
     3901 acgccaaaac gcgccgtggg gttactacat ctaccgctgg gggatgacaa ccgccgcctc
     3961 gatctggcgc tggaaagccc ggctaaaatg cgcccgaatc agccgctcac cgtcagggtg
     4021 aaagccagcg ttaaacacgg cgaaatgcca aaacagatca acgtgctggt ctccgcggtc
     4081 gatagcggtg tattgaatat caccgattac gcgacgccgg acccgtggca ggcgttcttc
     4141 ggtcaaaaac gctacggtgc ggatatctac gatatttacg gccaggtcat tgaagggcag
     4201 gggcggctgg cggcgttgcg ttttggcggc gatggcgacg accttacgcg cggcggaaaa
     4261 ccgccggtaa accatgccaa tatcatcgcg cagcaggcgc agccgatcac gctcaatgag
     4321 cagggcgaag gggtcgtaac gctgccgatt ggcgacttta acggcgaact gcgggttatg
     4381 gcgcaggcat ggacagcgga cgattttggt cgcggcgaaa gcaaagtcgt tgtcgccgcg
     4441 ccagtgattg ccgagctgaa tatgccgcgt tttctggcgg gaggggatgt ttcgcgactg
     4501 gtgctggacg tcaccaatct gaccgaccgc ccgcagacgc tgaatattgc gctcgccgcc
     4561 agtgggttac tggaactgct tagtcaacag ccgcaaccgg tcaacctggc gccgggcgtg
     4621 cgcaccacct tattcgttcc ggtacgcgcg ctggaaggtt ttggcgaagg cgaaatccag
     4681 gcgaccatta gcggtctgaa tctgccggga gaaaccctcg gcgcgcagca taagcagtgg
     4741 caaatcggcg tgcgtccggc ctggcctgcc caaacggtaa atagcggcat tgcgctggcg
     4801 ccgggagaga gctggcatgt accagagcag catctggcaa acgtctcgcc agccacgtta
     4861 cagggacaac tgctgttaag cggaaaaccg ccgctcaatc tggcgcgcta cattcgcgag
     4921 ctgaaagcat atccgtacgg gtgcctggaa caaaccacca gcgggttatt cccggcgctg
     4981 tataccaatg ccgctcaatt gcagtcgctc ggtattaccg gcgatagcga tgaaaaacgg
     5041 cgcgccgcgg tggatatcgg catctcccgc atactacaga tgcagcgtga taacggcggt
     5101 tttgcgctat gggatgaaaa tggggcggaa gagccctggc taacggccta cgcgatggat
     5161 ttcctcattc gcgcgggcga gcagggatat agcgtcccgc cggaggccat taaccggggc
     5221 aatgagcgac tgctgcgcta tctgcaggat cccggtacga tgctgattcg ttatagcgat
     5281 aatacccagg ccagtacttt tgccgctcag gcttacgccg cgctggtact ggcgcgtcag
     5341 cagaaagcgc cgctcggcgc gctgcgcgaa atctgggagc gccgtagtca ggcggcttca
     5401 ggactgccgc tgatgcaatt gggcatcgcg ttaaacacga tgggtgatgc cagacgcggc
     5461 gaagaggcca ttacgctggc tctgaatacg ccgcgtcagg acgaacggca atggatagcg
     5521 gattacggca gttctctgcg cgataacgct ctgatgttgt cgttactgga agagaacaac
     5581 ctcagaccgg acgcgcaaaa cgcgctatta agctcgcttt ctgagcaggc cttcggtcag
     5641 cgctggctct ctacccagga gaacaatgcc ttgttcctcg ccgcgcattc gcgacaggcc
     5701 agcgcgggcg cctggcaggc gcagacctcg ttagaggcgc agccgctgtc gggcgacaag
     5761 gcgctgaccc gtaatctgga tgctgatcag ctggccgccc ttgaggtgac gaacaccggt
     5821 agccagccgc tatggctgcg tctggatagc agcggctatc cctcatctgc gcctgagcct
     5881 gccagcaacg ttttgcagat tgaacgacaa atactgggga ccgatggtca gcgcaaatcg
     5941 ctgtcctcgt tgcgtagcgg cgaactggtg ctggtctggt taacggtagt ggccgatcgc
     6001 aatgtgccgg atgcgctggt ggtggacctg ctcccggccg ggctggagct ggaaaaccag
     6061 aatctggctg acagcagcgc cagcctgccg gagagcggta gcgaagtgca aaatctgctt
     6121 aatcagatgc agcaggcgga tattcagtat atggaattcc gcgacgatcg gtttgtggct
     6181 gccgtcgttg tcaatgaggg ccagcccgtg acgctggtct acctggcgcg cgcggtaacg
     6241 ccggggacgt accagcttgc gcaaccgcag gtggaatcga tgtacgcgcc tcagtggcgg
     6301 gcaaccggcg cgagcgaggg actgctgatt gtgacgcctt aaatgaacgg ttggcgtggt
     6361 aaacgtggcc gctggctgtg gctggcgggc gcgccgcttt ttattttcct ggcgttatgg
     6421 gcagcggata aactctggcc gctgccgctc aatgaggtcc atcctgcgcg ggtcgtggtc
     6481 gcccatgacg gtacgccgct gtggcgcttt gccgacgccg gggggatctg gcgttatccg
     6541 gtgacgattg aagaggtctc tccccgttac ctggaggcct taatcaatta cgaagatcgc
     6601 tggttctggc agcaccctgg cgttaaccct ttttccgtcg cgcgcgcggc atggcaggat
     6661 cttaccgccg ggcgcgttat ttccggcggc agtacgctga ctatgcaggt ggcgagactt
     6721 ctggacccgc attcgcgcac gttcggcggt aaaatccgcc agctttggcg cgccctccag
     6781 cttgaatggc atttgtccaa gcgcgatatc ctgacgttgt acctgaaccg cgcgccgttc
     6841 ggcggcacgc tacagggtat tggcgctgca agctgggcct acttcggcaa gccgcccgcg
     6901 cgcctgagct acgctgacgc ggcgctgctg gccgtattgc cgcaggcgcc gagccggtta
     6961 cgccccgacc gatggcctac gagagccgaa gcggcacgga ataaagtgct ggatcggatg
     7021 gcggagcagg gcgtctggcc tgccgaaacg gtacgcgagt cgcgtgaaga gccggtctgg
     7081 ctggcgccgc gtcaaatgcc gcaactggcg ccgctttttg cccgaatgat gttgagtaaa
     7141 agccggagcg acaaaattgt gaccacgctg gacgccgggt tgcagcggca actggaagat
     7201 ctggcgcggg catggaaagg gcggctgcct gcacgcagtt cattggcgat gatcgtcgtc
     7261 gatcataccg atatgagcgt gcgcggctgg gtaggatcgg tagaccttaa tgacgacagc
     7321 cgttttggtc atgtcgacat ggtaacggcg atccgatcgc cgggatcggt actcaaaccc
     7381 tttgtgtatg gtctggcgct ggatgacggc ttgatccatc ccgcatcact attacaggac
     7441 gttccgcgcc gcaccggaga ttaccgcccg ggaaacttcg atagcggatt tcacggcccg
     7501 gttagcatga gcgacgcgct ggtacgctcg ctgaatctgc ctgccgttca ggtgcttgaa
     7561 gcctatgggc cgaaacgatt tgcggcaaaa ctgcgtaacg tcggcctgcc gctatatttg
     7621 cctgctggcg cggcgcccaa tctttcgctg attctgggcg gcgcgggcgc gcggcttgac
     7681 gagatggcgg cggcatacag cgcgttcgct cgtcatggga aagcggcgaa actacggtta
     7741 cagccggacg atccgctgtc ggaaagacca ttaatgtcgc cgggagcggc gtggatcatt
     7801 cgacggatta tggcggatga agcgcaaccc ttgccggata acgcgctgcc gcgcattgtg
     7861 ccgttggcgt ggaaaaccgg caccagctac ggctatcgcg atgcgtgggc tattggcgtt
     7921 aacgcgcgct atatcatcgg catctggaca ggcagacccg acggcacgcc tgtggtgggg
     7981 caatttggtt ttgccagcgc ggtgccattg cttaaccagg tcaataatct gttactggcg
     8041 catacgggac gcctgccgga agatccgcgt ccgcagacgg taagccgcgg cgtcatttgc
     8101 tggccgggcg gacagactct gcctgccggg aacagcaact gtcgccgccg actggcgaca
     8161 tggctgcttg acgacagcca gccgcccacg ctgctgttac ctgagcagga agacatcaac
     8221 ggtattcgtt tcccggtctg gctggatgat acggggcggc gtgtcgctgc cgactgtccg
     8281 caggcgcgtg cgcatacgtt tatcgtctgg ccgcggccgc tggagccgtg gctgccgcct
     8341 gcggaaagac gtagcgcccg cttgcccgcg gcgtccgacc actgtccgcc gctacagggc
     8401 aatgatgccg cgccgttaat gctgtcagga gtgagggatg gcgcggtgat caggcaattg
     8461 ccaggccagg aaaacgtcac gctgcccgtc tcgactaccg gcggcaaagg gcgtcgctgg
     8521 tggtttttaa atggcgaacc tgttaatggc gaaaataatc gcctttcttt attactcaat
     8581 atcgctggac gttatcaact tgtcgtaatg g
//
LOCUS       DAJVKX010000163         8507 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.163, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000163 DAJVKX010000000
VERSION     DAJVKX010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8507
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.163"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(903..1278)
                     /gene="rnpB"
                     /locus_tag="OPY25_004005"
     ncRNA           complement(903..1278)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="OPY25_004005"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(1311..2456)
                     /gene="garK"
                     /locus_tag="OPY25_004006"
     CDS             complement(1311..2456)
                     /gene="garK"
                     /locus_tag="OPY25_004006"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HCS0929477.1"
                     /translation="MKIVIAPDSYKESLSAAEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGVERAAWVTGPLGEKVKACWGMSGDGKTAFIEMAAASGLALVPPE
                     KRNPLITTSRGTGELILQALESGASNIIIGIGGSATNDGGAGMMQALGAKLRDANGAD
                     IGYGGGSLHCLSNIDISELDPRLKLCAIRVACDVSNPLIGDNGASRIFGPQKGATEEN
                     IVELDRNLAHYADIIKKSLNVDVKAAPGAGAAGGMGAALMAFLGAELRSGIEIVTAAL
                     NLEEHIHDCTLVVTGEGRIDSQSIRGKVPIGVANVAKKYHKPVIGIAGSLTHDVGIVH
                     HYGIDAVFSVLTRIVTLEEAFRGAFDNIYRASRNVAAALAIGMRSAG"
     gene            complement(2554..3444)
                     /gene="garR"
                     /locus_tag="OPY25_004007"
     CDS             complement(2554..3444)
                     /gene="garR"
                     /locus_tag="OPY25_004007"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HCS0929478.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAA
                     GAETASTAKAIAEQCDAIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISDALKAKGVEMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGDIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGHGN
                     DDHSALACYYEKLAKVEVTR"
     gene            complement(3470..4240)
                     /gene="garL"
                     /locus_tag="OPY25_004008"
     CDS             complement(3470..4240)
                     /gene="garL"
                     /locus_tag="OPY25_004008"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HCS0929479.1"
                     /translation="MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWL
                     VLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVET
                     QEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQQTIQHIFARAKAHGKPCGILAP
                     VEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK"
     gene            4771..6342
                     /gene="garD"
                     /locus_tag="OPY25_004009"
     CDS             4771..6342
                     /gene="garD"
                     /locus_tag="OPY25_004009"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HCS0929480.1"
                     /translation="MANIEIRQESPSAFYIKVHETDNVAIIVNDHGLKAGTRFPDGLE
                     LTEHIPQGHKVALTDIPAHGEIIRYGEVIGYAVRDIPRGSWIDESLVELPKAPPLNTL
                     PLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKVIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNIALNPNFGGEVMVIGLGCEKL
                     QPERLLEGTEDVPAIAVENASIVRLQDEQHVGFKSMVDDILRVAERHLTKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAINEAVGKRLLDEMAWYDNYLDMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWYDLMDINAGTIATGEETIEDVGWKLFHFILDVASGRKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            complement(6582..7529)
                     /locus_tag="OPY25_004010"
     CDS             complement(6582..7529)
                     /locus_tag="OPY25_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCS0929481.1"
                     /translation="MNITIATLSELLVEFLAKKENQGFSSPGEFWGPYPSGAPAIFAD
                     QVAKLGFRSLLFSCVGNDAFGVMNITRLSRDGVNVQGISVLPNATTGSAFVSYRSQAQ
                     RDFIFNMPDSACGLLSADHLDETLLRQYRHFHIMGSSLFSFRLIDAVRKAISIVKENG
                     GTISFDPNIRKEMLKIREMSQAFEYILDYTDFFLPSDGELDYFGLSKSRDEEKIVARL
                     HKRGIAHVIIKRGARGASYYSKDEQHHVAGYPVKVVDPTGAGDCFGATFVSLFLAGYS
                     VPDALAHANAAGSLAISARGPMEGTSTLAQIKELMRQQN"
     gene            complement(7540..8373)
                     /locus_tag="OPY25_004011"
     CDS             complement(7540..8373)
                     /locus_tag="OPY25_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0929482.1"
                     /translation="MAKPSTSLLKRRLDIAEIVRKNGEIKVDDLAEMLSVSGVTIRND
                     LNYLEQQGYLKRSFGGAIYTAQPVRAAVSHEVVQSQALEHSVELELAKQVARLVCDDD
                     TVFLGAGEVLRKALPFLGDYRDLCLIINDLSHVAPARDYIDGEIVLLGGVLGRSGQAL
                     GGEIAIQSLQQFQPSCCLVMVDHISEDGTLNVKNESAAALLSECLRLSGQSIAVVAQR
                     PIHDIARYPVGKLNTLSAIITPQIVAAEYHSRFLADGLTNSYTNNECLTWINPTLHQA
                     R"
BASE COUNT         2053 a         2353 c         2001 g         2100 t
ORIGIN      
        1 gagttacaaa aacaagacag taacttagcc tgatttcaat caaaaaaaat ggtcgggata
       61 acgatatatt atggcgataa ccagcctatt ttatctccta ttttcgacat cccatgaaga
      121 cgatatttca atcaattacg ggacatttta tcgacaattc cagcgttaaa tttaaaacgt
      181 aatttctcaa atttaagtat aaaccgaagg taaatgcgct taaaaaccgt tacgcgtcac
      241 atttttttac cttatttgtt tgtaaagaaa catttaataa aattttaacc aaaatatttc
      301 atacatttaa ttttcatttg caacaaataa tttacaccgt tttcttgctg tttttcagga
      361 tgtaattttg tgaaagaaat cgattgcttt tcacttcaac taaaaagagc gcaatccata
      421 gcgttttgtg tttctcatca caaaaacgaa taatattatg tcaccacggc tgtcaattaa
      481 ttgccggatg gtgacactgg cgtcttctgc aacctctata cccttcaccg gcctgataag
      541 caaaaacccg ccgaagcgga ttttatgaag aggtgaaact gaccgataag ccgctttctt
      601 tcgggtatag cgtcgtggac agtcattcat cctgccgccc tgtaaaagca aaaacccgcc
      661 agcttacact gacggggttt atgaagaggt gaaactgacc gataagccgc tttcttttgg
      721 gtatagtgtt gtggacagtc attcatcctg tcgccctgta aaagcaaaaa cccgccgaag
      781 cgggttttat gaagaagtga aactgaccga taagccgctt tcttttgggt atagcgtcgt
      841 ggacagtcat tcatcctgcc gccctgtaaa agcaaaaacc cgccgaagcg ggttttatga
      901 agaagtgaaa ctgaccgata agccgggttc tgtcgtggac agtcattcat ctaggccagc
      961 aatcgctcac tggctcaagc agcctacccg ggttcagtac gggccgtacc ttatgaaccc
     1021 ctatttggcc ttgctccggg tggagtttac cgtgccacgg actgttacca gccgcgcggt
     1081 gcgctcttac cgcacccttt cacccttacc tgatcccact tgcgtgggcc atcggcggtt
     1141 tgctctctgt tgcactggtc gtgggtttcc ccccccaggc gttacctggc accctgccct
     1201 atggagcccg gactttcctc ccctccgccc gtctccccga aaggacgacg acgaagcggc
     1261 gactgtctgg tcagcttcgg cgcgcagtat agagggttcg cgcgactttg tcaccctgcg
     1321 ctgcgcattc ctatcgccag agcggcagca acatttctgg atgcccgata aatattgtca
     1381 aaagcgcccc gaaaagcctc ctccagcgtc acgatgcgcg tgagtacgct aaagacagcg
     1441 tcgatgccat aatgatgtac tattcctaca tcgtgcgtca ggctgccggc aatgccaatc
     1501 actggcttat gatatttttt cgccacattc gcgacgccaa tcggcacttt accgcgaatg
     1561 ctttggctat caatccgccc ttctcccgtc accaccagcg tacagtcgtg gatatgctcc
     1621 tccaggttca gtgccgccgt gacaatttcg atcccgctgc gtaattccgc accgagaaaa
     1681 gccattaacg ccgcccccat accgcctgcc gcgcctgcgc cgggcgccgc ctttacgtcg
     1741 acattcagcg atttttttat gatgtcggca taatgagcaa gattcctgtc cagctcaaca
     1801 atgttctctt cggtcgcgcc tttctgcggc ccaaaaattc gtgatgcgcc attgtcgccg
     1861 ataagaggat tggagacatc gcaagcgaca cgaatagcgc agagttttaa acggggatcg
     1921 agctctgaaa tatcaatgtt gcttagacaa tgaaggcttc cgccaccgta accaatatcc
     1981 gcgccgtttg catcgcgcag ttttgcgcct aacgcctgca tcatccctgc gccgccgtca
     2041 tttgtcgcgc tgccgccaat gcctataatg atattgcttg cgccgctttc cagcgcctgc
     2101 aatatcagct cccccgttcc ccgcgaggta gtaatcaaag ggttgcgttt ttctggcgga
     2161 accagcgcca gtccgctggc cgccgccatt tcaataaacg cggttttacc atccccggac
     2221 attccccagc aggctttcac tttttcaccc aacggcccgg tcacccatgc ggcgcgttca
     2281 acgccctgcg tcgcggcaat catggcttcg accgttcctt cgccgccatc ggcaaccgga
     2341 acagagacat attgcgcatc ggggaaaatt tcccgaaatc ctttttctat cgcctgcgct
     2401 acctcggcgg cagaaaggct ttctttatag gagtcggggg caattacgat tttcatagtg
     2461 gtagcctgtt actgcacaac gccggatggc gtttcactta tccagcctga aattcaggcc
     2521 cggatcgcta cacgccatcc gggcacaacg tcgttagcga gtgacttcca ctttcgccag
     2581 tttttcgtag tagcacgcca gcgcgctatg gtcgtcatta ccgtgtccat ccgcgcgtaa
     2641 cgcctgcatc atttccataa cggcggcggt cagcgggagc tgcgcgccaa cgccgtggga
     2701 ggtatccagc gcattcgcca gatctttaat gtgcagatcg atacggaaac ctggcttaaa
     2761 gtttctgtcc atgaccatcg gcgctttcgc atccagtacc gtgctgccag ccagaccgcc
     2821 acgaatcgcc tgatagacca aatccgggtt gacgcccgct ttagtcgcca gcgtcagcgc
     2881 ttcagacatg gcggcgatat tcaacgccac gatcacctgg ttagccagtt ttgtgacgtt
     2941 gcctgcgccg atatcgccgg tatgcaccac ggaacccgcc atcgctttca tcaggtcgta
     3001 gtacttgtcg aaaatggctt tatcgccccc caccatcacc gacagcgtgc catcaatcgc
     3061 cttcggctcg ccgccgctga ccggcgcatc caacatctca acgcccttcg ccttcagcgc
     3121 atcgctgatt tcacggcttg ccagcggcgc gatagaactc atatcaatca atacggttcc
     3181 cggcttcgcg ccttcgatga taccgttctc gcccagcgca acctctttca catgcggaga
     3241 gttaggcagc atcgtgatga tggcgtcaca ctgttcagcg atcgccttcg ccgtagaggc
     3301 cgtttccgcg cctgcggcaa tgacgtcggc aatcgcttca ggattacgat cggacaccac
     3361 cagcgaatac cctgctttca gtaagttttt gctcatgggc ttacccatga tgcctaagcc
     3421 aataaagcca actttcatcg tcatagcgtt ctctctttcc ataccaggat tattttttaa
     3481 aggtgtcggc aagcttctgc gtgctggcgc ggaatgcgcc taaatcgctg ccaacggcga
     3541 caaaggtcgc gccccattcc agataacggc gggcatccgc ctctaccggc gccagaatgc
     3601 cgcacggttt accgtgcgct ttagcgcggg cgaaaatatg ttgaatcgtc tgctgcacgt
     3661 cagggtgaga agcattgccg agatgaccca gcgcggcggc caaatcgcta gggccgacaa
     3721 aaatgccatc aacgccttcc gttgcggcga tggcatcaac attgtcgaca cccaactggc
     3781 tttcgatttg aacaataatg gtgatgtttt tgttcgactg cgcaaagtaa tcaggcaccg
     3841 tgccgaacat attcgcgcgg tgagaaacgg agacgccgcg aatgccttcc ggcgggtaac
     3901 gcgtcgaggc gacggcgcga gccgcttcct cttgcgtttc aacaaagggg atcaggaagt
     3961 tataaaaccc aatatccagc atccgtttga taatgaccgg ttcattggtt ggcacacgta
     4021 ccacaggcgc gctggcgctg cctttcaatg ccattaactg cggaattaag gtggtcacat
     4081 cgttcggcgc atgttcgcca tccagcacca gccagtcaaa tcccgccaga ccgagtactt
     4141 cggtggtgat tgggcttgcc agtgcagacc agcagccaat ctgcacctgt tgcgccgcca
     4201 gcgccgcttt aaacttattc gggaaaatag cgttattcat cgcttatacc ttcgcttatt
     4261 tctttaattc tctacatgtg atgccgccac catgacttat agcaacgaca ataaaaatgc
     4321 ttatttgaaa tcagaatggg tctccacatt ctatttctaa tgtggtacac atcctgtagc
     4381 acaatatacc gttctgatat ctttatcgtc ttttattatt atcatgatat tttcaaataa
     4441 ctcgtcagat acactgaatt cgccattcag tataaacagc ctatgtcgga taatcattgt
     4501 gcaaacgctc attaaaaagg gtttatttaa cgcttatttt tgagcatacg cccatgatac
     4561 tgggcgctaa tgcacacatt tacgctttgc ctgccctaca taaaaaattt cataatttgc
     4621 ggtgatctgg atcacgttct tatatctata ctcctgtcat tcttatttca ttatgcatga
     4681 actttatttc ttatattgag atttaacgat ttaaccataa ccaaaataga taatcctatt
     4741 tctatcatcc aggctggaga atgttgaaca atggccaata tcgaaattcg ccaggaatcg
     4801 ccatcggcgt tttatataaa agtacatgaa accgataatg tcgcaattat tgttaatgac
     4861 cacggcctta aagccggaac acgttttccg gatggcctgg aactgactga acatattccg
     4921 caaggccata aagtcgctct gacggatatc cccgctcacg gcgaaatcat ccgttatggc
     4981 gaagtcatcg gttatgcggt acgcgacatc ccgcgcggaa gctggatcga cgagtcgctg
     5041 gttgaactgc caaaagcgcc gccgctgaat acgctaccgc tggcgaccaa agtaccggaa
     5101 ccgctgccgc cgctggaagg ctacacgttt gagggctatc gtaacgccga tggcagcgtc
     5161 ggcaccaaaa atctgcttgg cattaccacc agcgtgcact gtgtggcggg cgtggtcgat
     5221 tatgtggtga aagtgattga gcgcgatctc ctgcccaaat acccgaatgt cgatggcgtt
     5281 gtagggctaa accatctgta cggctgcggc gtggcaatca acgcgccggc ggcggtcgtg
     5341 ccgattcgca caattcataa tatcgcgctc aaccccaatt ttggcggcga agtgatggtg
     5401 attggcctcg gttgcgaaaa actgcagccg gaacgactgc tggaaggcac cgaggatgtc
     5461 cccgccatcg ccgttgaaaa cgccagtatt gtgcgtttac aggacgagca gcatgttggc
     5521 tttaaatcaa tggtcgacga tattttgcgg gtcgccgaac gccatctgac gaaactgaac
     5581 cagcgccagc gcgaaacctg cccggcctcc gagctggtcg tcgggatgca atgcggcggc
     5641 agcgatgcgt tttctggcgt cacggcaaac ccggcggtgg gttatgcttc cgatctgctg
     5701 gtacgctgcg gcgcgaccgt catgttctcg gaggtcaccg aagtgcgcga tgccattcat
     5761 cttctgacgc cgcgcgccat caacgaagcc gtgggtaaac gcctactgga tgaaatggcc
     5821 tggtacgata actaccttga tatggggaaa accgatcgca gcgctaaccc gtcccccggc
     5881 aacaaaaaag gcggcctggc gaacgtcgtg gaaaaagcgc tgggctctat cgctaaatcg
     5941 ggtaagagcg ccattgtcga agtattgtcg ccgggccagc gccccaccaa acgcggcctg
     6001 atttacgccg cgacgcccgc cagcgatttc gtctgcggca cgcagcaggt cgcttccggc
     6061 attaccgtac aggtctttac caccggacgc ggcacgccgt acgggctgat ggcggtgccg
     6121 gtcattaaaa tggcgacgcg taccgagctg gcgaaccgct ggtatgactt aatggatatc
     6181 aatgcaggca ccatcgccac gggtgaagag acaatcgaag atgtgggctg gaagctattt
     6241 cactttattc tcgatgtcgc cagcggccgg aaaaagactt tctcagatca atggggattg
     6301 cataaccagc tggcagtgtt taaccccgca cctgtgacct gatctattct ggaaagcgcc
     6361 tcgcaaaaca tggcttaagg gccatgtttt catatgtttg ataaactgcg ccatgttcat
     6421 accggatatg gcaaaaacac ctaacccacc ataaaaccat tcaaattcaa taaattgaaa
     6481 ttctatgcca ggcgcaacct tacgtttctc actaatttga gtcgcagcac atgcaatttg
     6541 aggtatgtcg aatataacga cagcctatta atcaccttta cttaattctg ctgcctcatc
     6601 aattctttaa tttgtgccag cgtggacgtg ccttccatcg gcccacgcgc agagatagcc
     6661 agcgatcctg cggcattagc atgggctaaa gcatcgggta cggaatatcc cgcaagaaac
     6721 aggctgacaa aggttgcgcc aaagcaatcg ccagcgcctg taggatcaac cactttcacc
     6781 ggatacccag ccacatgatg ttgttcgtct tttgaatagt aactggctcc acgggcgcca
     6841 cgtttaatga tgacatgggc aattccacgc ttgtgaagcc ttgcgacaat tttctcttca
     6901 tcgcgggatt tgctcaggcc gaaataatcc agttcgccat cgcttggcag gaagaaatcc
     6961 gtgtaatcaa gaatatattc aaaggcctgc gacatttcgc ggatctttag catctcttta
     7021 cggatattag gatcgaaaga aattgtgcca ccattttctt ttacaatgct aatcgccttg
     7081 cgtacggcat cgatcaaacg aaaggaaaat aatgacgatc ccataatatg aaagtggcga
     7141 tattgcctga gtaatgtttc atcaaggtgg tcggcactca gcaaaccgca cgcactgtcc
     7201 ggcatgttga aaataaaatc tcgctgggcc tggcttcggt agctgacaaa agcactacct
     7261 gttgtggcgt tcggcagtac ggaaattccc tgtacattta cgccatcgcg cgacaatcgg
     7321 gtaatattca taacgccaaa ggcatcgttg ccaacacagc taaacaacaa tgaacgaaaa
     7381 ccaagtttag caacctgatc ggcaaatatg gcaggcgccc cactgggata cggcccccaa
     7441 aattcccccg gtgaggaaaa tccctggttc tctttttttg ccagaaactc gacgagcaat
     7501 tcactcaatg ttgcgattgt tatgttcatg cgttgtcctt catcttgcct gatgcagggt
     7561 cgggtttatc caggtcagac attcgttatt ggtatagctg ttggttaagc cgtcggccag
     7621 aaaccgtgag tggtactcag cggcgacaat ctgtggcgta ataatcgcgc tcagcgtatt
     7681 cagttttcct accggataac gcgctatatc atgaatcgga cgctgcgcca ccacggcaat
     7741 actctgtcca ctaaggcgca ggcattcact tagcaaagca gctgcacttt cgtttttcac
     7801 gttgagcgtg ccatcctcgc tgatatggtc caccatcacc agacaacatg acggttgaaa
     7861 ttgttgcaaa gattggatgg cgatttcgcc ccccagcgcc tgaccactgc gccccagtac
     7921 accgcccaac aacacaattt caccatcgat ataatcacgg gccggtgcaa catggctaag
     7981 atcgttgatg ataaggcaca gatcccgata atcgcccagg aaaggaagcg ctttacgcaa
     8041 cacctctccg gcccccagaa acacggtatc gtcgtcgcag accagacggg caacttgctt
     8101 agccagttca agctcgacgc tatgctctaa cgcctgcgac tgcaccactt catggcttac
     8161 cgctgctctg acgggttggg ccgtgtaaat cgctccgcca aaggagcgtt tcagatagcc
     8221 ttgctgctcc aggtaattga gatcattacg gatcgttacc cctgaaaccg ataacatttc
     8281 agccaaatcg tctactttta tttcgccgtt tttacggacg atttcggcaa tgtccagacg
     8341 ccttttcaac aggctggtag atggttttgc cacaacatac cctttttttc cgcttcgtcg
     8401 ggaagttatc ccgtgcttta actttcattt ttaaacttct gacaggggat gtcaattttg
     8461 caccacgtca ccgaatgctc aatgggaaac atcacaataa aatcaat
//
LOCUS       DAJVKX010000164         8455 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.164, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000164 DAJVKX010000000
VERSION     DAJVKX010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8455
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.164"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            390..986
                     /gene="wrbA"
                     /locus_tag="OPY25_004012"
     CDS             390..986
                     /gene="wrbA"
                     /locus_tag="OPY25_004012"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HCS0929483.1"
                     /translation="MAKILVLYYSMYGHIETMAHAVAEGAKKVDGAEVIIKRVPETMP
                     PEIFAKAGGKTQNAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLGGVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYSAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            1007..1234
                     /locus_tag="OPY25_004013"
     CDS             1007..1234
                     /locus_tag="OPY25_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HCS0929484.1"
                     /translation="MPTQEAKAHRVGEWASLRNTSPEIAEAIFEVAHYDEKLAEKIWE
                     EGSDEVLIKAFEKTDKDSLFWGEQVIERKNV"
     gene            complement(1268..2509)
                     /gene="agp"
                     /locus_tag="OPY25_004014"
     CDS             complement(1268..2509)
                     /gene="agp"
                     /locus_tag="OPY25_004014"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HCS0929485.1"
                     /translation="MKKSLLAVAVAGAVLLSSAVQAQTTPEGYQLQQVLMMSRHNLRA
                     PLANNGNVLAQSTPNAWPAWDVPGGQLTTKGGVLEVYMGHYTREWLVAQGLIPSGECP
                     APDTVYAYANSLQRTVATAQFFITSAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     RQQAVQAMEKARSQLHLDESYKLLEQITHYQDSPSCKEKHQCSLIDAKDTFSANYQQE
                     PGVQGPLKVGNSLVDAFTLQYYEGFPMDQVAWGGIHTDRQWKVLSKLKNGYQDSLFTS
                     PTVARNVAAPLVKYIDKVLVAERVSAPKVTVLVGHDSNIASLLTALDFKPYQLHDQYE
                     RTPIGGQLVFQRWHDGNANRDLMKIEYVYQSARQLRNAEALTLKSPAQRVTLELKGCP
                     VDANGFCPLDKFDNVMNTAAK"
     gene            complement(2642..3148)
                     /locus_tag="OPY25_004015"
     CDS             complement(2642..3148)
                     /locus_tag="OPY25_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein disulfide oxidoreductase"
                     /protein_id="HCS0929486.1"
                     /translation="MAGKLRRWLREAAVFLALLIAIMVVMDVWRAPQAPPAFAATPLH
                     TLTGESTTLATLSEERPVLLYFWASWCGVCRFTTPAVAHLAAEGENVMTVALRSGGDA
                     EVARWLARKGVDFPVVNDANGALSAGWEISVTPTLVVVSQGRVVFTTSGWTSYWGMKL
                     RLWWAKTF"
     gene            complement(3138..3761)
                     /locus_tag="OPY25_004016"
     CDS             complement(3138..3761)
                     /locus_tag="OPY25_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCS0929487.1"
                     /translation="MKYMIVLLLALFSTLSIAQETAPFTPDQEKQIKNLIHAALFNDP
                     ASPRIGAKHPKLTLVNFTDYNCPYCKQLDPMLEKIVQKYPDVAVIIKPLPFKGESSIL
                     AARIALTTWRDHPQQFLALHEKLMQKRGYHTDDSIKQAQQKAGATPVTLDEKSMETIR
                     TNLQLARLVDVQGTPATIIGDELIPGAVPWDTLEAVVKEKLAAANGG"
     gene            complement(3758..5644)
                     /locus_tag="OPY25_004017"
     CDS             complement(3758..5644)
                     /locus_tag="OPY25_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCS0929488.1"
                     /translation="MMILFRRILFCLLWLWLPVSWAAESGWLRSPDNDHASIRLRADT
                     SANSETRLLLDVKLENGWKTYWRAPGEGGVAPSIAWKGDMPEVSWFWPTPSRFDVANI
                     TTQGYHDEVTFPMIVRGTPPATLRGVLTLSTCSNVCLLTDYPFSVTPTVQNADFAHDY
                     ARAMGKVPLRSGLTDSLDVGYRPGELVVTATRAAGWSSPGLYLDTIDDVDFAKPRLRV
                     EGDRLQATVPVTDSWGEKAPDLRDKSLTLVLADGAIAQESTQTIGAAPAQTPDNAALP
                     FWQVVMMALIGGLILNLMPCVLPVLGMKLGSILLVEEKSRSHIRRQFLASVAGIIASF
                     MALAAFMTLLRLSNHALAWGVQFQNAWFIGFMALVMLLFSASLFGLFEFRLPSSMTTK
                     LATYGGNGMSGHFWQGAFATLLATPCSAPFLGTAVAVALTASLPTLWGLFLALGLGMS
                     APWLLVAIRPGLALRLPRPGRWMNVLRRILGLMMLGSAIWLATLLLPHFGFTASKSAQ
                     DTVQWQPLSEQAIQSALAQHKRVFVDVTADWCITCKVNKYNVLQKEDVQAALQQPDVV
                     ALRGDWTLPSDAITDFLKTRGQVAVPFNQVYGPGLPEGEALPTLLTRDAVLQTLKKAK
                     GITQ"
     gene            complement(5693..6055)
                     /locus_tag="OPY25_004018"
     CDS             complement(5693..6055)
                     /locus_tag="OPY25_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein"
                     /protein_id="HCS0929489.1"
                     /translation="MAKQQRMGWWFLCLACVVVMVCTAQRMAGLHALQMQATASAAVV
                     SAPSSTDDGSPVTPCELSAKSLLAAPPVLFEGAILALYLLLSLLAPVRVMRLPFSPPR
                     AISPPTLRVHLRFCVFRE"
     gene            6291..7211
                     /gene="cbpA"
                     /locus_tag="OPY25_004019"
     CDS             6291..7211
                     /gene="cbpA"
                     /locus_tag="OPY25_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HCS0929490.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFNRQFQQHEGQPYNAEDFDDIFSSIF
                     GQHGRHSHHRHAARGHDIEIEVAVFLEETLEEHQRTISYSVPVYNAFGLVEREIPKTL
                     NVKIPAGVSNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVNQDLEVVLPLA
                     PWEAALGAKVSVPTLKERILLTIPPGSQAGQRLRIKGKGLASKKHTGDLYAIIKIVMP
                     PKPDEKTAALWQQLADAQSSFDPRQQWGKA"
     gene            7211..7516
                     /gene="cbpM"
                     /locus_tag="OPY25_004020"
     CDS             7211..7516
                     /gene="cbpM"
                     /locus_tag="OPY25_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HCS0929491.1"
                     /translation="MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNADWQ
                     FDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP"
     gene            8170..>8455
                     /gene="iraM"
                     /locus_tag="OPY25_004021"
     CDS             8170..>8455
                     /gene="iraM"
                     /locus_tag="OPY25_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HCS0929492.1"
                     /translation="MEWKVVDTVISPSTGVSFSCIHSLKNLRLTLWYQADVYMPPGSI
                     IIPFNKGVLINDKLYPVTVYNVTRFNPVLWKSLKENSHCPGNCNPKPEACS"
BASE COUNT         2119 a         2325 c         2130 g         1881 t
ORIGIN      
        1 gccattactg acctccgtca tagattagac atcatattgc ataggtaatg aggagtatct
       61 cctcgcgccg cgtatgaacg atatcatcag taacgccgcg taaaattaag catagtgaaa
      121 aacgccgtgg taggccgctt accgaaatat tctgcaacat cagaagccga atatgcagaa
      181 taataaccat gagaaataaa taagttattc ttatacttgg aaaaatcaaa gcgcttaaaa
      241 atgtatcatt ttgcaacaaa ggtcgccaaa ttaattattg ttataaatca aagaaatggc
      301 gctgaaattt gcactcttca caggagggca tatctttaaa tagacgtagc gaatcgctac
      361 acacctgatt aatctgagga gtagtacaaa tggcaaagat tctggtgctc tattattcca
      421 tgtacggaca cattgaaacc atggcgcacg cggtggcgga aggggcaaag aaagtcgacg
      481 gcgcagaggt cattataaag cgtgtgccag aaacaatgcc gcctgaaatc ttcgcaaaag
      541 ctggcggtaa aacgcaaaac gcaccggttg ccaccccaca ggagctggcg gattacgatg
      601 ccattatttt tggtacgcca acccggtttg gcaatatgtc aggccagatg cgtaccttcc
      661 tggaccaaac cggcggactg tgggcatccg gcgcgctata cggcaagctc ggcggcgtgt
      721 tcagttctac cggaacgggc ggcggccagg agcagaccat cacctcgacc tggactacgc
      781 ttgcccatca tgggatggtg attgtcccga taggctattc cgcacaggaa ctgtttgacg
      841 tctcccaggt tcgcggcggt acgccttacg gcgcaacgac tatcgctgga ggcgacggtt
      901 cacgtcaacc aagccaggag gaactctcta tcgctcgcta tcagggggaa tacgtcgccg
      961 gtctggcagt caaactcaac ggctaatctt caacaggagg attcgaatgc caactcaaga
     1021 agcaaaagcg caccgcgtcg gcgaatgggc aagcctgcgt aatacgtcgc cggaaattgc
     1081 cgaagccatt tttgaagtcg ctcactatga cgagaaactg gcagaaaaaa tatgggaaga
     1141 aggtagcgat gaggtgctga tcaaagcctt tgagaaaacg gacaaagact cgctcttctg
     1201 gggcgaacaa gtcatcgaac gtaagaacgt ataacacaaa cgcccccgcc tgcgcggggg
     1261 catacggcta ttttgcagca gtgttcatga cgttatcgaa cttatccagc ggacagaagc
     1321 cgttcgcatc caccggacat cctttcagtt ccagcgttac cctttgcgca ggcgatttga
     1381 gcgttaacgc ttccgcatta cgtaactgcc gggcgctctg gtagacatac tcgattttca
     1441 tcaaatcccg gttagcgtta ccgtcatgcc agcgttggaa gacaagctga ccaccaatcg
     1501 gcgttctctc atactggtca tggagctgat agggtttaaa atccagcgcc gtcagcagcg
     1561 acgcgatatt ggaatcatgc cccaccagca cggtaacctt cggcgcgcta acgcgctcgg
     1621 caaccagcac cttatcgata tattttacca gcggcgcagc gacattgcgc gccaccgtgg
     1681 gtgaggtaaa caggctgtcc tggtagccgt ttttcagttt tgacagcacc ttccactgcc
     1741 gatcggtgtg gatcccgccc caagcgacct gatccatcgg aaagccttcg taatattgca
     1801 gggtaaacgc atccaccagc gagttcccta ctttcagcgg cccctgcacg ccaggctctt
     1861 gctgatagtt cgcgctgaag gtatctttcg cgtcgattag cgaacactga tgcttctctt
     1921 tgcaggacgg cgagtcctga taatgcgtta tctgctcaag cagtttataa ctctcatcaa
     1981 gatgtagctg actacgcgcc ttttccatcg cctgtacggc ctgttgccgg aacgcggcgg
     2041 aatcatcggt aatcaccgga ttgaaggtag ggtccatagt gcccattttt tcctgatgat
     2101 gaacaggaat atcacagccg gggaaagcgc tggtaatgaa aaattgcgcg gtggcgacgg
     2161 tgcgctgcaa actattcgca taggcatata ccgtgtcggg cgccggacat tctcccgacg
     2221 gtatcagccc ctgcgcgacc agccattcac gtgtgtagtg tcccatatag acttccagca
     2281 cgccgccttt cgtcgtcagt tgcccgccgg gaacgtccca cgccggccag gcgttcggcg
     2341 tcgactgcgc cagtacgttg ccattattcg ccagcggcgc ccgcagatta tggcggctca
     2401 tcatcagcac ctgttgtaat tgataacctt ccggcgttgt ctgcgcctgt acggcggatg
     2461 acaacaaaac agcccctgcc acagcaacag cgagtaatga ttttttcatc cctatgacct
     2521 cttgttgtta tcaaatcgtt ctgagtgtga cagaaatgga tcatttttcc gggaacgatt
     2581 tcgcaaaacg gaggtttttc ttacagtaaa cgcgttagcg ccgggaaacc ccggcgcata
     2641 ttcagaacgt ttttgcccac cacagccgaa gcttcatgcc ccaatagctg gtccagccgc
     2701 tggtggtgaa cacaacccga ccttgtgaaa ccaccaccag cgttggcgtc acgctgattt
     2761 cccagccagc ggataaggcg ccgttagcat cattgacgac cgggaagtca acgcccttgc
     2821 gcgccagcca gcgggcaacc tcagcatcac cgccggagcg gagcgcaacg gtcatgacgt
     2881 tttccccttc cgccgccagg tgagcgaccg caggcgtggt aaagcggcat accccgcacc
     2941 agctggccca aaaatagagc agtacggggc gttcctcgct caaggtcgcc agagttgtcg
     3001 actctcccgt cagcgtatgt aatggtgtcg cggcaaacgc cggaggcgcc tgcggcgcgc
     3061 gccagacgtc catgaccacc attatcgcga tgaggagcgc cagaaaaacc gcggcttcac
     3121 gcagccaacg ccgcagttta cccgccattg gcagccgcca gtttttcttt caccaccgct
     3181 tccagcgtat cccagggcac tgcgcccgga atcagctcgt cgccaatgat cgtcgctggc
     3241 gttccttgca cgtcgaccag tcttgccaac tgcaaattag tgcgtatcgt ttccatgctt
     3301 ttttcatcca gcgtcactgg cgtcgcccct gctttctgct gggcctgttt aatactgtca
     3361 tccgtatggt aaccgcgctt ttgcataagt ttttcatgta gcgcgaggaa ctgttgcgga
     3421 tgatcgcgcc aggtggtcag cgcaatacgc gccgccagta tggaactctc tcctttgaat
     3481 ggcagcggtt taataatgac cgcaacgtca ggatatttct gcacaatctt ttccagcatc
     3541 ggatcgagct gtttgcagta cgggcagttg taatccgtaa agttcaccag cgtcagctta
     3601 gggtgtttag cgcctatccg cgggctggca ggatcgttaa acaacgccgc atggatcaga
     3661 tttttaatct gcttttcctg atccggcgta aaaggagcgg tttcttgcgc gatgctcagc
     3721 gtcgaaaaca gcgccagcag taaaacaatc atgtatttca ttgggttatt cctttcgctt
     3781 ttttcaacgt ttgtaatacc gcatcgcggg tcagcaaagt gggcagtgcc tccccttccg
     3841 gcaaaccggg gccatatacc tgattaaacg gcacggcgac ctggccgcgc gttttcagaa
     3901 aatctgtaat ggcatcggac ggcagcgtcc agtctccccg cagcgccaca acatccggct
     3961 gttgcaaggc ggcctgcaca tcctcttttt gcaggacgtt gtatttattc actttacagg
     4021 taatacacca gtccgcagtg acatcgacaa atacccgctt atgctgcgcc agcgccgact
     4081 ggattgcctg ttcactcaac ggttgccact gaaccgtgtc ttgcgcgctc tttgacgcag
     4141 tgaagccgaa atgcggcagg agtaacgtcg ccagccagat agccgacccc agcatcatca
     4201 gaccgaggat cctgcgcagg acattcatcc aacgcccggg gcgcggtaaa cgtagcgcaa
     4261 gccctggtcg tatcgcgacc agtagccacg gcgcgctcat tcccaggcca agcgcaagga
     4321 acagccccca cagcgtcggc agcgacgccg tgagcgccac cgcgaccgcc gtgcccagaa
     4381 acggcgcgct acaaggcgtc gccagcagcg tggcgaacgc cccctgccag aaatgtcccg
     4441 acataccgtt accgccgtaa gtggccagtt tcgtggtcat agatgaggga agcctgaact
     4501 caaaaagccc gaacaggctg gcgctaaaca acaacatcac cagcgccata aaaccaataa
     4561 accatgcatt ctggaactgg actccccagg ccagcgcatg gtttgacagg cgaaggaggg
     4621 tcataaacgc cgccagcgcc ataaatgacg caatgatacc ggcgaccgaa gccaaaaatt
     4681 gtcgcctgat gtgagagcgg cttttttcct ctaccaataa aatagagcca agtttcatgc
     4741 ccagaacagg cagtacgcag ggcattaaat taagaatcag tccgccgatt agcgccatca
     4801 ttacaacttg ccagaaaggt agcgccgcat tgtccggcgt ttgcgctggc gcagcgccaa
     4861 tggtttgcgt gctctcctgg gcgatagcgc catcggctaa cacgagggtc agcgatttgt
     4921 cgcgcaaatc gggcgccttt tcgccccaac tgtccgtcac cggcaccgtc gcctgtaacc
     4981 tgtcgccctc tacgcgcagg cgaggcttcg caaaatcgac gtcatctatg gtgtcaagat
     5041 agagcccggg cgatgaccag cccgccgctc gcgtagcagt gaccaccagt tctcccgggc
     5101 gatagccaac gtcaagcgag tccgttagcc cactgcggag cggaacttta cccatcgccc
     5161 gcgcatagtc atgggcaaaa tcggcattct gcacagtggg cgtcacggaa aaggggtaat
     5221 cggtcaacag acaaacattg ctgcaggttg ataacgtcaa cacaccgcgc aaggtcgccg
     5281 gcggcgtacc gcgcacgatc atcggaaagg tcacctcgtc gtgatatccc tgggtggtga
     5341 tattcgccac atcaaagcgc gagggggttg gccagaacca gcttacctca ggcatgtcgc
     5401 ctttccaggc gatagagggt gccacgcccc cttcccccgg cgcgcgccag taggttttcc
     5461 agccgttttc cagtttgaca tccagcaaca gccgggtctc actgttagcg gacgtatcgg
     5521 cacgtagccg tatgctggca tggtcgttat cgggcgaacg cagccagccg ctttccgccg
     5581 cccaggagac gggcagccaa agccataaca ggcagaacag tatccgcctg aataaaatca
     5641 tcatattttt tctccgtgaa tgagtaatta accgttagta ataaccggtc tgtcattcac
     5701 ggaagacaca aaatcgtaga tgtacccgta atgtgggcgg cgaaatagcc cgtggaggcg
     5761 aaaacggcag gcgcatgacc cggacaggcg ccagtaagga aagcagtaga taaagcgcaa
     5821 ggatagcacc ttcaaagagt actggaggcg ccgccagcag cgacttggcg cttaattcgc
     5881 agggagtgac cggcgagccg tcatctgtcg aggagggagc gctgaccacc gcagcagagg
     5941 ccgtcgcctg catctgcaag gcgtgcaggc ccgccatgcg ttgcgcggta caaaccatta
     6001 ccacgacaca tgcaaggcaa agaaaccacc agcccatccg ttgttgtttc gccattgcgc
     6061 cctcactgtt taacgcgagt tatcttagcc actggcgcgg ttttggcaac ctttcccctg
     6121 taaagttatg tcggcgcgct gcgcaacctt ctgatagtcg aacaacgtaa tttattctta
     6181 ctaatgatat aactggtgtt ttcatacgca cttttcaggt ttaccctaca cttagtggag
     6241 aaaccttttt ggggtccctt ctgtatgtat tgatttagcg agatgatgct atggaactta
     6301 aggattatta cgccattatg ggcgtgaaac cgacggacga tctcaagacg attaagaccg
     6361 cctatcgccg actggcccgc aagtaccatc cagatgtcag caaagaaccc gatgccgaag
     6421 cccgtttcaa agaggttgct gaagcatggg aagtgctgag tgatgagcaa cggcgcgccg
     6481 agtatgacca gttatggcaa caccgtaacg atccacaatt taatcgccag ttccagcaac
     6541 acgaaggcca gccgtataac gccgaagatt ttgatgatat tttctcgtct atttttggtc
     6601 agcacggtcg tcattcgcac caccgccacg ccgcacgcgg tcatgatatc gaaattgaag
     6661 tggcggtatt cctggaagaa acgctggaag agcaccagcg tacgattagc tattccgtcc
     6721 ccgtttataa cgcgttcggc ctggtggagc gggaaattcc caaaacattg aatgtgaaaa
     6781 tcccggctgg cgtcagcaac gggcaacgaa tcagactgaa aggccagggc acgccggggg
     6841 aaaacggcgg acctaatggc gatttatggc tcgttatcca tattgccccg catccgctct
     6901 ttgatatcgt caatcaggat ctggaagtcg tccttccgct tgccccatgg gaggcggcgc
     6961 tcggcgctaa ggtgtctgtg ccaacgctta aagagcgtat tttgctgacc attccccccg
     7021 gcagccaggc aggtcagcgg ctgcgtatca aaggaaaagg attagccagt aaaaagcaca
     7081 ctggcgatct ctatgccatc atcaaaatcg ttatgccgcc gaaacctgac gagaaaacag
     7141 ctgccctgtg gcaacaactg gcggacgcgc agtcgtcctt tgacccacgc cagcaatggg
     7201 ggaaagcata atggctaaca tcactgtcac ctttaccatc accgaatttt gtttgcacac
     7261 cggcgtgacg gaagaggagc taaacgaaat cgtcggactt ggcgtaattg agccttacga
     7321 agacgataac gccgactggc aattcgacga tcgcgcagcg agcgtggtac aacgcgcgct
     7381 acgcttacgc gaggagctgg cgctcgactg gccagggatc gcggtcgcgt taacgctgct
     7441 ggaagagaat tcacggctgc gcgaagaaaa ccggttactg ctgcaacgcc tttctcgctt
     7501 tatctcgcat ccctaatcca cgataaaggc aataaaccga gggtgggctt tctgcccacc
     7561 ccggatttac atacacccgg tataatacca gaatgcctct gacatacttc ccgcaacgga
     7621 agaaatatag cctttcaccg cgcacaagcc gatcaacgaa ccgccaatgt cagccattaa
     7681 tgcgccattg cgaagatcat cgtttaaata aagaccagcc acacgctcac attttttaga
     7741 ttcgtcggtt atttttacac gttagcgatc atttattgcc tgaagaatat attctttcac
     7801 tgttttgtac tctctggttg atacgtatct tctccctgtc aatgccgggt aaaatgtacc
     7861 gctgcgctta caggttgcgg tatttataaa taagaaatac aacagtcact tacagtttaa
     7921 taattgagcg ttataacatc cactaccgcc caatatttac accacgtata aaatacaaaa
     7981 atgtaataga atgtaaacaa aataagagca taaaataaat aacttattaa aaaatcaata
     8041 taaatagagt ggtcaataaa aaacgatcgt tttcaacgag ttatgtttct cagattttca
     8101 tctatcctga ataggcttgc ggaaaatgta atttacacca ttgactattt cacttaaaag
     8161 gtttctgtaa tggaatggaa ggtcgttgat acagttataa gtccctctac cggagtgtcg
     8221 ttctcatgca tacatagcct aaaaaatctt agattgacct tatggtatca agcagatgtt
     8281 tacatgcctc caggtagcat tatcatcccc tttaataagg gggtcttaat aaacgataaa
     8341 ctttatcccg ttactgttta caacgttacc aggtttaatc ctgttctatg gaaatcgctt
     8401 aaagaaaata gccactgtcc tggtaactgc aatcctaaac cagaagcttg cagtt
//
LOCUS       DAJVKX010000165         8350 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.165, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000165 DAJVKX010000000
VERSION     DAJVKX010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8350
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.165"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            255..1214
                     /locus_tag="OPY25_004022"
     CDS             255..1214
                     /locus_tag="OPY25_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A deacylase LpxR family protein"
                     /protein_id="HCS0929493.1"
                     /translation="MNKYSYCATMIAAILSTTTMANASSLAISVANDDAGIFQPSLNA
                     LYGHKAADRGDYTAGLFLGYSHDLTDASQLSFHIAQDIYSPSGANKRKPEAVKGDRAF
                     SAFLHTGLEWNSLATNWLRYRLGTDIGVIGPDAGGQEVQNRAHRIIGAEKYPAWQDQI
                     ENRYGYTAKGMVSLTPAIDILGVNVGFYPEVSAVGGNLFQYLGYGATVALGNDKTFNS
                     DNGFGLLSRRGLIHTQKEGLIYKVFAGVERREVDKNYTLQGKTLQTKMETVDINKTVD
                     EYRVGATIGYSPVAFSLSLNKVTSEFRTGDDYSYINGDITFFF"
     gene            complement(1263..2021)
                     /locus_tag="OPY25_004023"
     CDS             complement(1263..2021)
                     /locus_tag="OPY25_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HCS0929494.1"
                     /translation="MKLLKAVPAVVMLAGGVFASLYAAADDSVFTVMDDPSTAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTAMTWYGQRTAWSLWGNASNTSSNDERSSEKYAVGV
                     RNRFNMTDYDYTFGQASWLTDRFNGYRQRDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DEHTDDTTETQPLGYASGSYAWQLTDNAKFTQGVSVFGAEDTTLNSETALNVAINEHF
                     GLKVGYNLTWNSQPPESAPEHTDRRTTVTLGYKM"
     gene            2310..3242
                     /gene="pfkB"
                     /locus_tag="OPY25_004024"
     CDS             2310..3242
                     /gene="pfkB"
                     /locus_tag="OPY25_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HCS0929495.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPESKLRCSAPVFEPGGGGINV
                     ARAIAHLGGTATAIFPAGGATGEHLVALLADENVPVSTVDAKDWTRQNLHVHVESSGE
                     QYRFVMPGATLDDDEFRQLEEQVLEIESGAILVISGSLPPGVKVEKLTQLISAAQKQG
                     IRCIIDSSGDALTAALALGDIELVKPNLKELSALVNRDLTQPDDVRKAAQELVQSGKA
                     RRVVVSLGPQGALGIDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAQDASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSAQ"
     gene            3339..3629
                     /gene="ghoS"
                     /locus_tag="OPY25_004025"
     CDS             3339..3629
                     /gene="ghoS"
                     /locus_tag="OPY25_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HCS0929496.1"
                     /translation="MASGDITRYVITVTFHEDSLTEINELNNHLTRSGFLLTLTDDEG
                     NVHELGTNTFGFVSAQSADEIKALVAGLAKSALDKDVDITVATWEAWSKNAQ"
     gene            3736..4596
                     /locus_tag="OPY25_004026"
     CDS             3736..4596
                     /locus_tag="OPY25_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCS0929497.1"
                     /translation="MWQAISRLLSEQVGEGEIELRNELPGGEVHAAWHLRYAGHDFFV
                     KCDEREMLRGFTAEADQLELLSRSKTVVVPKVWAVGSDRDYSFLVMDYLSPRPLDAHN
                     AFILGQQLARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGITFGNIDAIVEHVQQRLASHQPQPSLLHGDLWSANCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTDQPPQIYDGYQSVSPLPLDFLDRQPIYQLYTLLNRARLFGGQHLATA
                     QKAMDRLLAV"
     gene            complement(4639..5175)
                     /locus_tag="OPY25_004027"
     CDS             complement(4639..5175)
                     /locus_tag="OPY25_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HCS0929498.1"
                     /translation="MTYQQAGRIAILKRVVGWVIFIPALLSTLISVLKFMYAHSEKQE
                     GINAVMLDFTHVMIDMMRVNTPFLNVFWYNSPTPNFQGSLNIGFWLIFILIFVGLAMQ
                     DSGARMSRQSRFLREGVEDQLILEKAKGAEGLTREQIESRIVVPHHTIFLQFFPLYIL
                     PVIIIVLGYFFFSLLGFM"
     gene            5324..5992
                     /gene="hxpB"
                     /locus_tag="OPY25_004028"
     CDS             5324..5992
                     /gene="hxpB"
                     /locus_tag="OPY25_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HCS0929499.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDITRRH
                     ELPDTLRLRIDMVVDLWFAQQPWNGPDRQEVTNRVIARAITLIEETRPLLPGVREAVA
                     LCKAQGLLVGLASASPLHMLEKVLTMFELRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGLIAAKAARMRAIVVPAEENQHDPRFALANVKLNSLTELTAA
                     HLLG"
     gene            6130..6729
                     /locus_tag="OPY25_004029"
     CDS             6130..6729
                     /locus_tag="OPY25_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460287.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCS0929500.1"
                     /translation="MGFIMTAEGHLLFSIASAVFAKNAELTPALAHGDWWHIIPSAIL
                     TCLLPDIDHPKSFLGQRLKWVSKPIARAFGHRGFTHSLLAVFALLATFYLKVPDTWII
                     PADALQGMVLGYLSHIVADMLTPAGVPLLWPCRWRFRLPILAPRKGNQLERFLCMALF
                     AWAVWMPQSMPENNVIRWSSQMITILQMQFNRFINHQID"
     gene            6866..8257
                     /gene="tcyP"
                     /locus_tag="OPY25_004030"
     CDS             6866..8257
                     /gene="tcyP"
                     /locus_tag="OPY25_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HCS0929501.1"
                     /translation="MNFPLIANIAVFVILLFVLAQARHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGADSQVLKDSIQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTFIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIETSYVGKVAD
                     LSVPQLVLSFVPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLVA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLAIMFV
                     VHGILLGVNGISPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPVWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKT
                     ILDSEEDAELAHR"
BASE COUNT         2014 a         2104 c         2144 g         2088 t
ORIGIN      
        1 tcgtattata tgcataatcg tgaagccaat aatttctcgc actcagatag cgaatgaaaa
       61 atggatattc aataatatct ggcgcatgtt ttttaacacc atttttcaac attaaggcaa
      121 cgtatcctct caatgactcg ctgctggcag gagtttagtt atatttaaag gtttaataag
      181 cactgcgcat catgctgctg tgcttattac tttgtaaaaa taagagtatt cactttcata
      241 ttcaggggta aaaagtgaac aaatacagct attgcgcaac gatgattgcc gccatactca
      301 gtacgaccac aatggccaat gccagtagcc ttgctatttc agtggcgaat gatgatgcag
      361 gtatatttca accatcctta aatgcccttt acgggcacaa ggctgcagac cggggtgatt
      421 atactgccgg gctcttttta ggctacagcc acgatctcac tgacgccagt caactctctt
      481 ttcatatcgc gcaagatatt tattctccat ctggcgccaa taaaagaaag cctgaagccg
      541 tcaaaggcga ccgcgcgttc agcgcctttc ttcataccgg actggagtgg aattcattag
      601 ccaccaattg gttacgttat cgtttaggta ccgatatcgg cgttattggt cctgacgcag
      661 gcggtcagga ggttcagaat cgggcgcatc gaataatagg cgcagaaaaa taccctgcct
      721 ggcaggatca aattgaaaac cgttatggtt acacggcaaa aggaatggtc tcccttacgc
      781 cagctattga tattctgggt gtcaatgtgg gcttctatcc agaagtctct gctgtcggcg
      841 gcaatctctt ccagtatttg gggtacggcg caaccgttgc gctgggaaat gataagacct
      901 tcaactctga taatgggttt gggttattgt cccgccgagg gttaatacac actcaaaaag
      961 agggattgat ctataaagta tttgctggcg ttgagcgcag ggaagttgat aaaaactaca
     1021 cgttacaggg gaaaacgctg caaacaaaaa tggaaacggt ggatattaat aaaaccgtgg
     1081 atgaatatcg cgtcggtgcc accatcggct attctcccgt cgcattttct ctttctttaa
     1141 acaaagtcac gtcggaattt cgcaccggag acgactattc ttatatcaac ggcgacatca
     1201 ccttcttctt ctgaggcgtc accacggaat aaccgggtta cgtaacgtaa cccggcgcaa
     1261 tattacatct tatagcccag cgttaccgta gtgcggcgat cggtatgttc aggcgctgat
     1321 tcaggcggct gcgagttcca cgttaaatta taccccacct ttagaccaaa atgttcgtta
     1381 atggcgacat tgagggctgt ttccgaattt agtgtggtgt cttctgcgcc aaatactgac
     1441 accccctgtg taaacttagc attgtcagtt aactgccagg catagctgcc ggaagcataa
     1501 cccaacggct gcgtttcagt ggtatcgtcc gtatgttcgt catagcgaac ccctggaccg
     1561 aattcaaaac ggaagctgtg cactggacca ttaaggaact gccgcccgta accggcggtc
     1621 agtacgtcgc gctgacgata accgttgaaa cggtctgtca gccaactggc ctggccaaag
     1681 gtataatcat aatccgtcat attaaaacgg ttacgcacgc ctaccgcata tttttctgaa
     1741 gagcgttcat cattagagga ggtattgctg gcattgcccc ataatgacca ggcggtacgt
     1801 tgtccatacc aggtcatcgc cgtgtcagcc gttaaggaag aacttttagt attgcctgac
     1861 tgagcaaggt agcccgcatt cagattacct tcaaaaggtt ttttcgcggt ggagggatca
     1921 tccatgacag taaaaacgga atcatcggcg gcggcataca gagacgcgaa cacgccaccc
     1981 gccagcataa ctacagcggg tactgccttc aaaagcttca tttatataga gtccgtacaa
     2041 ctaaaaaaga gaccacgacg gtcccggaaa ctttcatagg gatcaatgac aaacgcccct
     2101 ggaaaggtag cgaattataa gaagccccga ataacatagc aatcaattac tatttcattt
     2161 tttgaataag aaccctcccg aagcattcat ttatttatat aactttacat cgtacttctt
     2221 taaataaaga tccggaaaat catattgtta attccttcac tttccgggga ttaagtgcca
     2281 gactgaaatc agcctaacag gaggtaacga tggtacgtat ctatacgttg acgcttgcgc
     2341 cctctctcga tagcgcaaca atcacgccgc aaatttatcc cgaaagtaaa ctgcggtgct
     2401 ccgcgccggt attcgaaccc ggcggcgggg gtattaatgt cgctcgcgcc attgcgcatc
     2461 ttggcggcac cgcgaccgca attttcccgg ctggcggcgc taccggcgaa catctggtcg
     2521 cactactggc tgacgaaaat gtccccgtgt ctaccgtcga tgcgaaggac tggacgcgtc
     2581 agaacctgca cgtccacgtc gagtccagcg gcgaacaata tcgttttgtt atgcccggcg
     2641 ccacgctgga cgatgacgaa tttcgccagc ttgaagaaca ggtactggaa attgaatccg
     2701 gggcaattct ggttatcagc ggcagccttc cgcccggcgt taaggtcgag aaactcacgc
     2761 aactgatttc cgccgcgcag aagcaaggca ttcgctgcat tattgatagc tctggcgacg
     2821 cgctcaccgc tgcgttggcg cttggcgata tcgaactggt gaaacctaac ctgaaagaat
     2881 tgagcgcgtt agtcaatcgc gatctgacgc agcctgatga tgtgcgtaaa gcggcccagg
     2941 aattagtgca aagtggcaag gctcgccggg tagtggtctc tctggggccg caaggggcgc
     3001 tgggcataga cagtgagaat tgcatccagg ttgttcctcc cccggtgaaa agtcaaagta
     3061 ctgtcggcgc aggcgacagt atggtgggcg cgatgacgtt aaaactggcg caagacgcgt
     3121 cgctggaaga gatggtgcgc ttcggtgtgg cggcaggcag cgccgctacg ctcaatcaag
     3181 gtacgcgtct gtgttctcat gacgataccc aaaaaatata cgcctatctt tccgcgcaat
     3241 aatcgtttcc ccctcgccga gggggatacc ggaaaatcgg ttaacgggcg gcgcatccgc
     3301 cgctgttaaa aacacagttg ctcccaacga ggtgaacgat ggccagtggc gatattaccc
     3361 gttatgttat taccgtaacc ttccatgaag attccctgac cgagattaac gaactcaata
     3421 accatctgac gcgcagcggt tttttgctga cattaacgga cgatgaaggg aatgtgcatg
     3481 agctcggcac caatacgttt ggctttgtta gcgctcagag cgctgatgaa atcaaagcgc
     3541 ttgtcgccgg acttgcgaaa agcgcgttag ataaggatgt cgacattacc gtggcgacct
     3601 gggaggcgtg gagtaaaaac gcacaataag tgccattccc gccgcggcgc gtccgcgatg
     3661 tgcgttagtt cgtatttttt aaccgcattt ttgcgctaac cttatgatct ggcagacaac
     3721 gtggggagag acattatgtg gcaagctatc agtcgtcttt taagcgagca agtcggtgaa
     3781 ggcgaaatcg aactgcgtaa tgaactgcca ggcggagaag ttcatgccgc atggcattta
     3841 cgttatgccg gccatgattt tttcgtgaag tgcgatgaac gagaaatgct tcgcggtttt
     3901 accgctgaag ccgatcagct ggagctgctc tcccgcagta aaaccgttgt tgtgcctaag
     3961 gtatgggcgg taggttcgga tcgggattac agctttttag tcatggacta cctctcgccc
     4021 cgcccgctgg atgcccataa tgcgtttatt cttgggcaac agctggcgcg cctgcaccaa
     4081 tggagcgacc aacctcaatt cggcctcgat tttgataacg cgctctctac cacgccgcag
     4141 ccgaatacct ggcaacgccg ttggtcgact tttttcgccg aacagcgcat tggctggcag
     4201 cttgaactcg ccgcggaaaa aggcattacc tttggtaata ttgacgccat tgttgaacat
     4261 gttcagcaac gtctggcgtc gcatcaaccg cagccttctc ttttgcatgg cgatctatgg
     4321 tcggcgaact gcgcgcttgg ccctgacggc ccctatatct tcgatccagc ctgctattgg
     4381 ggcgacagag aatgcgatct ggcgatgctg ccgctgcata ccgatcagcc accgcagatt
     4441 tatgacggct atcagtccgt ttcgccgcta ccgctggatt ttctcgacag gcagccgatt
     4501 taccagctct acaccctgct taatcgggca aggctgtttg gcggtcagca cctggctact
     4561 gcgcaaaaag cgatggatcg gctgcttgcg gtataggtac agcccacacc ggatacgggc
     4621 tatccggcat ttttcagttt acatgaaacc taacaaggaa aagaaaaagt agccgagcac
     4681 gataataatg accggcaaaa tatagagcgg gaaaaactgt aaaaagatgg tatggtgcgg
     4741 caccacgata cgtgactcta tctgctcacg cgttagtcct tccgcgcctt ttgctttttc
     4801 caggatcaac tgatcttcca cgccttcacg taaaaaacgt gactggcggc tcattctggc
     4861 gccggaatcc tgcatcgcca gcccgacaaa aatcagaata aaaatgagcc agaaaccgat
     4921 attcaggctt ccctgaaaat tcggcgtcgg cgagttgtac caaaaaacat tcagaaacgg
     4981 cgtattcacg cgcatcatgt ctatcattac gtgggtaaaa tccagcatta ccgcatttat
     5041 cccctcctgc ttttcactgt gcgcatacat aaatttaagg actgagatga gcgtggaaag
     5101 cagtgccgga ataaaaataa cccacccaac aactcttttt aggattgcaa tgcgtccagc
     5161 ttgttgatac gtcatgagtt ccccttgata aagacgcgtc gttttggcct aagtctacct
     5221 gttgattccc gttttcgcct gatctttaag ggcgatatac taagaacatg gtcataatga
     5281 acgcttaatt cgttattttt taatctcaac aggagaggtt gtgatgtcaa ccccacgtca
     5341 aattcttgct gcaattttcg atatggatgg actattgatc gattccgaac cgctctggga
     5401 tcgcgctgaa ctggacgtga tggcaagttt aggcgtagat attactcggc gccatgaact
     5461 gccagacacg cttaggctac gcattgatat ggttgtcgat ctctggtttg cgcagcaacc
     5521 gtggaacggc cccgatcgcc aggaagtgac aaaccgtgtt attgcccgcg cgattacgct
     5581 tatcgaagag acgcgccctc ttttgccggg tgtgcgcgaa gctgtggcgc tgtgtaaagc
     5641 gcaggggcta ttagtggggc ttgcctcggc atcgccgctg catatgctgg aaaaagtgct
     5701 caccatgttt gaactgcgcg acagttttga cgcgctggcc tctgcggaaa aattgcccta
     5761 cagcaaaccg cacccgcagg tctatctgga ttgtgcggcc aaattaggcg ttgatccatt
     5821 aacctgcgtg gcgctggagg attcggtgaa tggtttaatc gcggcaaagg cggcgcgaat
     5881 gcgcgccatt gtggtgccag cagaagaaaa ccagcatgat ccgcgctttg cgctggcgaa
     5941 tgtcaaactt aactcactga cagagctgac ggcggcgcat ctactcggtt aagatgtttc
     6001 cgaaacaaag tcaacgggca attagccgct gagccagacg gcaagcggct ttgacagaga
     6061 caaagagtta caacgtcacc acttccgcct actgtataaa aaccctatac tgtatgaatt
     6121 gacagtttaa tgggttttat catgacggcg gaaggacatc ttcttttttc tatagccagc
     6181 gcggttttcg ccaagaatgc cgagttaacg cccgcccttg cgcacggcga ctggtggcat
     6241 attattcctt cggctatttt gacctgtctg ctgccggata tcgatcaccc caaatctttt
     6301 cttggtcagc gcctgaaatg ggtatcgaaa ccgatcgccc gcgcattcgg tcaccggggg
     6361 tttacccata gtctgctggc ggtctttgcc ctactggcga ccttttatct caaggttccg
     6421 gatacgtgga ttatcccggc ggatgcgctg caaggcatgg tactcggcta tttaagccat
     6481 atcgtcgcgg atatgcttac ccccgcaggc gttcccttac tgtggccgtg tcgctggcgt
     6541 ttccgcctgc ctattctggc gccgcgcaag ggcaatcaac tggagcgatt tttatgtatg
     6601 gcgttgtttg cctgggcggt gtggatgccg caatccatgc cggaaaacaa cgtcatacgc
     6661 tggtcttcgc agatgatcac tatcctgcaa atgcagttca atcgttttat aaatcaccag
     6721 attgattagt aaatcaacgc caaagtcatt ttaggtataa accattccat ttgaatataa
     6781 gagccagctc acagttctgc taatcttgcg cgaacagaat cgctaaaaca cagcgcttca
     6841 taataaaaaa atcaggagaa cggggatgaa ttttccatta attgcgaaca ttgcggtgtt
     6901 cgtcattctg ctgtttgtac tggcgcaggc ccgtcataaa cagtggagtc tggctaaaaa
     6961 agtgcttgtc ggccttgtga tgggcgtggt ctttggtctg gccctgcaca ccatttatgg
     7021 cgctgacagt caggtgttaa aagactccat tcagtggttc aatattgtcg gcaacggtta
     7081 tgtgcaattg ctacaaatga ttgtgatgcc gctggtattc gcctctattt taagcgccgt
     7141 ggcacgactg cataacgcct ctcaattggg gaaaatcagt tttctgacta tcggcacgct
     7201 gctgtttact acctttatcg cagcgctggt gggcgtgctg gtcaccaatc tgttcggact
     7261 gacggcggaa ggtctggttc agggcggcgc ggaaaccgcg cgtctgaatg ccattgagac
     7321 gagctatgtc ggcaaagtgg ccgatctcag cgtgccgcaa ctggtgctgt cttttgtacc
     7381 gaaaaatccg tttgcggatc tgactggcgc aaatcctacg tctattatca gcgtggtgat
     7441 tttcgccgca ttcctgggcg tggccgcgct taaactgctg aaagatgatg cgccaaaagg
     7501 cgagcgtgtg cttgttgcta tcgataccct gcaaagctgg gtgatgaagc tggtgcgtct
     7561 ggtgatgcaa cttacgcctt acggcgtact ggcgctgatg acgaaagtgg ttgccggctc
     7621 taatttgcag gacatcatta agcttggaag cttcgtggta gcgtcatatc ttggtctggc
     7681 gataatgttt gtggttcacg gcatactatt gggcgtgaac gggattagcc cgctgaaata
     7741 tttccgcaag gtgtggccgg tgctgacatt tgcctttacc agccgctcca gcgccgcctc
     7801 cattccactt aatgtcgaag cgcaaacccg ccgtctgggc gtgccggagt ccatcgccag
     7861 ctttgctgcc tcttttggcg cgaccatcgg ccaaaacggt tgtgccggtc tttatcctgc
     7921 gatgttagcg gtaatggttg cgccgacggt cggcatcaac cccttagacc ccgtatggat
     7981 agccacgctg gtgggtatcg ttaccgtaag ttcggcgggt gttgccggcg ttggcggcgg
     8041 cgcgaccttc gccgcgctga ttgtgctgcc tgccatgggc ttaccggtca cgctggtcgc
     8101 gctgttaatc tccgtcgaac cgttgattga tatgggccgt accgcactga acgtgagcgg
     8161 ctcaatgacc gcgggtacgc tgaccagcca gtggctgaag cagaccgata aaaccattct
     8221 cgatagcgaa gaagacgctg aactggcgca tcgataatac attatcggga gttcacatcg
     8281 tctgagacac gacgatcggc aactcaaaat gtctgtcact aaaaacgccg gtctccagta
     8341 ccggcgtttt
//
LOCUS       DAJVKX010000166         8330 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.166, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000166 DAJVKX010000000
VERSION     DAJVKX010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8330
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.166"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            128..1891
                     /locus_tag="OPY25_004031"
                     /pseudo
     CDS             128..1891
                     /locus_tag="OPY25_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459238.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
     gene            1967..4108
                     /gene="ldcC"
                     /locus_tag="OPY25_004032"
     CDS             1967..4108
                     /gene="ldcC"
                     /locus_tag="OPY25_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HCS0929502.1"
                     /translation="MNIIAIMGPHGVYYKDEPIKELERALQSLGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSEINQLNEYLPLYAFINTNSTLDVSVHDMRMALWF
                     FEYALGLAEDIATRIHQYTNEYLDNITPPFTKALFTYAKEGKYTFCTPGHMAGTVYQK
                     SPPGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYMVTN
                     GTSTSNKIVGMYAAPAGSTLLIDRNCHKSLAHLLMMSDVVPLWLKPTRNALGILGGIP
                     KREFTRDSIARKVAETAQAQWPVHAVITNSTYDGLLYNTNWIKQMLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGDRVPGKVIFETQSTHKMLAAFSQASLIHIKGEYDEETFNEA
                     FMMHTSTSPSYPIVASIETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDSWF
                     FDIWQPEEVDEAECWPVTPGETWHGFTDADDDHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLTEFKRAYDLNLRV
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRQHDLPELMLRAFEVLPEMIMTPHQAW
                     QRQIKGEVETVALDQLPGRVSANMILPYPPGVPLLMPGERITQQSRAVLDFLLMLCSI
                     GQHYPGFETDIHGAKRNEDGVYQVRVLKHAC"
     gene            4164..4553
                     /locus_tag="OPY25_004033"
     CDS             4164..4553
                     /locus_tag="OPY25_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCS0929503.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFDLLSEAWREERDSW
                     KGDLALNGQYVIELFSFPFPPARPSRPEACGLRHLAFSVENVENAVAHLEKHQVKCEP
                     IRIDPYTGKRFTFFNDPDGLPLELYEQ"
     gene            4616..5908
                     /gene="tilS"
                     /locus_tag="OPY25_004034"
     CDS             4616..5908
                     /gene="tilS"
                     /locus_tag="OPY25_004034"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCS0929504.1"
                     /translation="MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVT
                     LRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAF
                     AQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRET
                     RKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCA
                     EQERLLDELLASDLTDCITTEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDAL
                     ERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKTVAGQHETTVAWPVWQTPLALP
                     AGLGTVQLVPGGELRRPREEESVSIRFKAPGLLHIVGRHGGRKLKKIWQEQGIPPWRR
                     DTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA"
     gene            complement(5992..6252)
                     /gene="rof"
                     /locus_tag="OPY25_004035"
     CDS             complement(5992..6252)
                     /gene="rof"
                     /locus_tag="OPY25_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HCS0929505.1"
                     /translation="MSMNETYQPINCDDYDSLELACMHHLILTLTLKDGEVLQAKAND
                     LILRKNVEYLLAEVSGESCELRLDKIASFSHPEIGTVVVSES"
     gene            complement(6239..6439)
                     /locus_tag="OPY25_004036"
     CDS             complement(6239..6439)
                     /locus_tag="OPY25_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HCS0929506.1"
                     /translation="MEKYCELVRKRYAEIASGDLGYVPDALGCVLKVLNEVAADSALS
                     ESVREKAAYAAANLLVSDYVNE"
     gene            6637..7182
                     /locus_tag="OPY25_004037"
     CDS             6637..7182
                     /locus_tag="OPY25_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HCS0929507.1"
                     /translation="MALKATIYKAVVNVADLDRNRFLDAALTLARHPSETQERMMLRL
                     LAWIKYADERLQFTRGLSAEDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQASDV
                     ALFAYNSRAAQIWWQQHQSKCAQFANLSVWYLDDGQLAQLSEFADRTMTLQATIQDGA
                     IWLSDARNNLEIQLTAWQQPS"
     gene            7179..7601
                     /gene="arfB"
                     /locus_tag="OPY25_004038"
     CDS             7179..7601
                     /gene="arfB"
                     /locus_tag="OPY25_004038"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCS0929508.1"
                     /translation="MIAISRTVSIADNELEITAIRAQGAGGQHVNKTSSAIHLRFDIR
                     ASGLPEYYKQRLLTASHHLISDDGVIIIKAQEFRSQELNREAAIARLVAVIKELTAEQ
                     KSRRATRPTRASKERRLSSKAQKSSVKALRGKIRRPLD"
     gene            7633..>8330
                     /gene="nlpE"
                     /locus_tag="OPY25_004039"
                     /gene_synonym="cutF"
     CDS             7633..>8330
                     /gene="nlpE"
                     /locus_tag="OPY25_004039"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006899150.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HCS0929509.1"
                     /translation="MVRTAILSVAAACTLFALIGCNNRAEVDALQPAQAAELKPMQQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYQGVREEPSSFASYGTWARTADKLVLTD
                     SNGEKSYYRAKGNALEMLDREGNPVASQLNYTLVPVTASLPVTPMPLRGMYVYRADAA
                     TFTDCATGKRLPVASNAQLERGYLAAKGEAEKPVLLTVEGHFVFAANPDTGEPVKTLI
                     ADKNVKFAPGKDCT"
BASE COUNT         1950 a         2096 c         2399 g         1885 t
ORIGIN      
        1 gacgaggaaa aatgagacgc cgatgagctg atgtgattaa acgcaacggc atgttctccc
       61 tgacactgta gcaactgcca ggcgtgtggc cagggcaggc agtgaactac ccttcaagga
      121 gaaaattatg ggattgcaaa aaacactggc gctcagcgcc gtagcggcag ggatcatgtt
      181 gagcttatcc ggtgcgcagg ccgcgccgct gcttagcagt agtgagccaa tgaccattaa
      241 cgccagcgat ctggcggcga aagagaaagc gctgacggat tttccgttaa tggaggcagt
      301 gaaatcctct atccagacgt tggataacag cgcggtcgaa caaatcgaac cggggcgcgc
      361 cgctaacccg gcaaacgtaa aacgcgttga aagtattctg aaagaggccg actgggatta
      421 tctgttcccg atgcgcgcgc cggaatacac ttactctaac ttcctgaaag cgataggtaa
      481 attcccggcg gtttgtggta cctacaccga tggacgcgat agcgacgcta tctgccgtaa
      541 aaccctggct actatgtttg cgcattttgc ccaggagacg ggcggtcacg aaagctggcg
      601 tgacattccg gaatggcgtc aggcgctggt ctatctgcgc gaagtcggct gaacagaagg
      661 gcaaaaaggc ggctacaacg gcgaatgtaa cccggatgta tggcagggcc agacctggcc
      721 gtgcggtaaa gataaggacg gcgatttcct cagctatttt ggccgcgggg caaaacagct
      781 ttcttataac tacaactatg ggcctttctc tgacgcgatg tatggcgacg ttcgccctct
      841 gctggataaa cccgagctgg tggcggatac ctggatgaac ctggcgagcg ccgtcttctt
      901 ctttgtgtat ccgcagccgc cgaagccgtc tatgctacat gtgattgacg gtacctggca
      961 gccaaacgat cgcgataaag caaacggcct ggtatcaggt ttcggcgtca ctattcagat
     1021 catcaatggc ggcgtggagt gcggcggcgc agatgagaat gcgcagtcgc ttaaccgtat
     1081 cgcctactac aaagagtttg ccaactacct gaaagtgccg gtgccggctg acgaagtgtt
     1141 gggctgtaaa aagatgaagc agttcgatga aggcggcgct ggcgcgttac cgatctattg
     1201 ggaacaagac tggggctgga gcgccgatac tgcggacggt aaaacctatt cctgccagtt
     1261 agttggatat cagacgccgt ataccgcctt taaagagggc gactacacga aatgtgtaca
     1321 gcattatttc aacgttaatg tcgtcgatga taacggaacc actgaaccgg atgtcacgcc
     1381 aactccggcg ccagtgacgg atgaaaacgt ggcaccagtc gcgcgcattg ccgggccggt
     1441 cggggcggtg gaagccggta gccaggtttc actcaacgcg gaaggatcga ccgacgcgaa
     1501 tggcgacaag ctcacctata cctggatgtc gcaggatggc aaaacgctga gcggccagga
     1561 taaagccgtt gtgattttca acgcgccgga tgtcactcag aacacccagt atgtggtgaa
     1621 tctgaccgtt agcgacggta cgctctccag tacagcggtt tatacgctga atgtgaaagc
     1681 gaaggccgcc gctgcggatg acgaagataa gaccaccagc taccctgcct ggagcagcag
     1741 ccagaaatgg aatccgggcg acatcgtcaa cagtaatggc gcattgtacc agtgcaaacc
     1801 gttcccggaa ggctcatggt gtaatgttgc gcctgcctac tatgagcccg gcgtagggat
     1861 tgcctgggcc gatgcatgga acgcattgta ataagataaa tcctgtcggt gctttgcatc
     1921 ggcaggattg ttactatgct tatctcaggt tttttcagga gaaagcatga acatcatcgc
     1981 cattatgggg ccgcacgggg tttattataa agatgaaccc atcaaggagc ttgagcgtgc
     2041 attacaatcc ctgggatttc aaattatctg gccgcaaaat agcgttgact tgttgaagtt
     2101 tattgaacat aacccgcgca tctgcggcgt tatttttgac tgggatgaat acagtctcga
     2161 cctttgtagc gaaatcaacc agctaaatga ataccttcct ctctacgcct ttatcaatac
     2221 caactccacg ctggacgtta gcgttcacga tatgcgcatg gcgctgtggt tttttgagta
     2281 tgcattgggg ctggctgaag atatcgcgac gcgcattcat caatatacaa acgaatatct
     2341 cgataatatt acgccgccgt ttaccaaagc gctgtttacc tacgccaaag aaggaaaata
     2401 taccttttgt acgccggggc atatggcggg aacggtgtat cagaaaagcc cgccaggctg
     2461 tctgttttat gacttttttg gcggcaatac cttaaaggcc gatgtgtcga tttcggtgac
     2521 tgaactggga tcgctgctgg atcacaccgg gccgcatctg gaagcggaag agtatatcgc
     2581 ccgtactttt ggcgccgagc agagttatat ggtgacgaac ggtacgtcga cctcgaataa
     2641 aattgtcggt atgtatgccg cgcctgcggg aagtacgcta cttattgatc gtaattgcca
     2701 taaatcgctg gcgcatttgc tgatgatgag cgatgtggtg cctctctggt tgaagccgac
     2761 gcgcaatgcg ctcggcattc tcggcggtat tcctaagcgt gaatttaccc gcgacagcat
     2821 tgcgcgtaag gtggcggaaa ccgcgcaggc gcaatggccg gtgcatgcgg ttatcaccaa
     2881 ttcgacttac gatggtctgc tgtataacac taactggatc aagcagatgc tggacgttcc
     2941 ctcgatccat tttgattccg cctgggtacc ctatacccat ttccatccga tctaccaggg
     3001 gaaaagcggg atgagcggcg atcgggtgcc cggaaaagtg attttcgaaa cgcaatccac
     3061 ccataaaatg ctggcggctt tttcgcaggc gtcgcttatt catatcaaag gggaatatga
     3121 cgaagagacg tttaacgaag cgtttatgat gcacacttct acatcgccga gctatcccat
     3181 tgtcgcctct atcgagaccg cggcggcgat gctgcgcggc aatccaggga aaagattgat
     3241 taatcgttcg gtggaacggg cgctccattt tcgtaaagaa gtacagcggt tacgtgaaga
     3301 gtccgatagc tggttctttg atatctggca gccggaagag gttgatgagg ccgaatgctg
     3361 gccggtcacg ccgggagaaa cctggcatgg cttcaccgat gctgatgacg atcatatgtt
     3421 cctcgatccg gttaaggtga caatcctgac gccggggatg gatgaacagg gcaacatgag
     3481 cgaagagggg atacccgccg cgctggtggc gaagttcctc gatgagcgag gcgtggtggt
     3541 ggaaaaaacc gggccgtata atctgctgtt tttgttcagc atagggattg ataagacccg
     3601 tgcgatgggg ctgctgcgcg gactgacgga atttaaacgc gcctacgatc ttaacctgcg
     3661 cgtcaaaaat atgttgccgg atctgtatgc ggaagatccg gatttttatc gcaatatgcg
     3721 cattcaggat ctggcgcagg ggatccataa actgatccgc cagcacgatc ttccggagct
     3781 gatgctgcgg gcgttcgagg ttttaccgga gatgatcatg accccgcacc aggcctggca
     3841 gcgtcagatc aaaggtgagg tggaaaccgt ggcgctcgat caactgccag ggcgcgtttc
     3901 cgcgaatatg atcctgcctt atccgccagg cgttccgctg ttgatgcccg gcgagaggat
     3961 cacgcaacag agtcgggccg tgctcgattt tctgctgatg ctctgttcga ttggccagca
     4021 ttatcccggt tttgaaacgg atattcacgg cgcgaaacgg aatgaagacg gggtgtacca
     4081 ggtacgagtc ttaaaacacg cctgttagct tgcctgacga gaatgtgacg agtaacgtac
     4141 tgataatcaa taaaggagac gctatgctgg gattaaaaca ggttcatcac atcgcgatca
     4201 ttgcgacaga ctatgcggtg agcaaggcgt tttattgcga tattctgggg ttcgatctgc
     4261 taagcgaagc ctggcgggaa gagcgtgact cgtggaaggg cgatttggcg ctaaacgggc
     4321 agtatgtgat tgagcttttc tcttttccct tccctccggc gcgtccaagc cgacctgaag
     4381 cctgcggtct gcgccatctg gctttcagcg tggaaaatgt ggaaaacgcc gttgcgcatc
     4441 tggaaaagca tcaggttaag tgcgaaccga tacgcatcga tccgtatacc gggaagcgct
     4501 ttactttttt caacgatccg gacggtttac cgcttgagct gtatgagcag taaggcttgt
     4561 cattaagacg ctcgccaggt aacgttgccg ggctaagtca ctataagcat ggatcatgac
     4621 cactctcacg ttgaatacct cgttactctc ttctcgccgt attctggctg cctttagcgg
     4681 tggcctggat tctacggtgc ttctgcatca actggtgttg tggcgagaac gccatcctga
     4741 cgtcacgctg cgtgctatcc atattcatca cggtttaagc cctcatgctg atagctgggt
     4801 gcggcattgc gaaaccgtat gcgaacgctg gcaggttccg ctggtagtgg agcgggtgac
     4861 gttggcggat aatggcctgg gtatcgaggc ccatgcgcgt gaagcgcgct accgggcgtt
     4921 cgcacagacg ctattgcctg gcgaagtgct ggcaaccgcg cagcaccttg acgatcagtg
     4981 tgaaacattc ctgctggcgt taaagcgcgg cagcggtccg gccggacttt ccgcgatggg
     5041 agaacgctcg ccttttgccg gaactctgct tcttcgcccg ctgttgagag aaacgcggaa
     5101 gacgctggaa cagtgggctg tgcgtcatgg cttatgctgg attgaagatg aaagcaatca
     5161 ggatgacgcc tacgatcgca attttttacg cctgcgcgcg cttccgctct tacagcagcg
     5221 ctggccgcat tttcctgcgg cggtagcccg tagcgcgacg ctctgcgccg agcaagaaag
     5281 gctgctggac gagcttctgg ccagcgatct tacggactgt atcacgacgg agggaacatt
     5341 gcggctctct ccattaatgt cgatgagcga tgtgcggcgg gcggcgattt tgcgtcgctg
     5401 gctggcgatg cgtaatgcgc cgatgccctc tcgcgacgcg ctggaacgta tctggcagga
     5461 ggtggcgctg gcgcgcgacg atgcctctcc ctgtttacgc tttggcgatc acgagattcg
     5521 ccgttatcag tcgcaactgt ggtggattaa aaccgtagcc ggacaacacg aaacgacggt
     5581 cgcctggccc gtctggcaaa caccgctggc gctgcctgcc ggcttaggga cggtacagct
     5641 cgttcctggc ggcgaactgc gccgaccgcg agaggaagaa tccgtcagca ttcggtttaa
     5701 agcgccaggg ttgctacaca ttgtgggacg tcacggcgga cgtaaattaa agaaaatctg
     5761 gcaggagcag gggatcccgc cctggcgacg agacaccacg ccgctgttgt tttacggcga
     5821 aacgctgatt gcggctgcgg gtgtttttgt gacgcgtgag ggagcagcag aagataaaga
     5881 aggggtgagt ctggtttggc atgcctgatg gcgctgcgct tatcaggcct acgtatcgca
     5941 tggaacgtag gccggataag gtgcttgcac caccatccgg caacaaaata ctcaggattc
     6001 gctaactacc acggtaccaa tttccgggtg gctgaaactg gcgattttat cgagacgaag
     6061 ttcacaagac tcgccggaaa cctcggcaag cagatactct acgtttttac gtaagatcaa
     6121 atcgttcgct tttgcctgca aaacctcgcc atcttttaac gttagcgtca gtattaaatg
     6181 atgcatgcag gcaagctcaa gactatcgta gtcatcgcaa ttaatgggtt gatacgtttc
     6241 attcattgac ataatcgctc accagtaagt tcgcggcagc ataagctgcc ttttccctga
     6301 ccgactctga aagggcgcta tctgccgcca cttcattaag cactttcaat acacaaccca
     6361 gcgcatccgg gacataccct aagtctccgc tggcgatttc cgcataccgc ttgcgtacta
     6421 actcacaata tttttccaca tgccctcctg tcagcattct gacttaaccg tggatgcaag
     6481 tctaagccta cgaagttaaa tcttgtttag caaggtgact ataccatact catttgcgca
     6541 atatcagcgc ctgacgcgag tgggtaaaag attcgttaac agccttttag cgcggttttc
     6601 gctacaatgg gcgcctgatt cgaaaggagt tttctcatgg cgcttaaagc gacaatttat
     6661 aaagccgtcg tcaatgtggc tgaccttgat cgcaaccggt ttctggatgc ggcattgacg
     6721 ctggcgcgtc acccttctga aacgcaggag cgcatgatgc tgcgcctgtt ggcatggata
     6781 aaatatgctg atgaacggtt gcagtttaca cgcgggctca gcgcggaaga tgagccggag
     6841 gcctggctgc gcaacgatca tctgggcatc gatctctgga tagagctggg gctgccggat
     6901 gagcgccgta ttaagaaagc ctgtactcag gcgagcgacg tcgcgctctt tgcttataac
     6961 tcccgggcgg cgcaaatctg gtggcagcag catcaaagca agtgcgcgca gttcgctaac
     7021 ctgtccgtct ggtatctgga tgacgggcag ctggcgcagc tcagtgaatt tgccgatcgt
     7081 accatgacgc tacaggcgac gattcaggac ggcgcaatct ggctttctga tgctcggaat
     7141 aatctggaaa tacagctaac cgcctggcaa cagccctcat gattgccatc tcccggacgg
     7201 tctccatagc cgataatgag ctggaaatta cggccattcg cgcgcagggc gcgggtggtc
     7261 agcacgtaaa taagacctct agcgcgattc atttgcgctt tgacattcgg gcctctggcc
     7321 tgccagagta ttataaacag cgtttgctga cggccagcca ccatctgata agcgatgatg
     7381 gcgtcattat cattaaggcg caggagttcc ggagccagga gctcaaccgg gaagcggcta
     7441 tcgccaggct ggttgccgtc ataaaagaat taaccgcgga gcagaaaagc cgtcgcgcaa
     7501 cccgtccgac gcgtgcctcg aaagagcgcc gcttgtcctc aaaggcgcaa aaatcttctg
     7561 taaaggcgct tcgcggcaaa attcgtcgtc cactggattg acgggcagga atagcaattt
     7621 cataaggatt ttatggtgag aacagcaata ttgtcagtag cggcagcctg tacgctattt
     7681 gcattgatag ggtgtaataa ccgtgcggaa gttgacgccc tgcaacctgc gcaggcggcg
     7741 gaattaaaac ccatgcagca aagctggcgc ggcgtgctgc cctgtgcgga ttgtgaaggt
     7801 attgaaacgt cactgtttct ggaaaaagac ggcacatggg tgatgaacga gcgctatcag
     7861 ggcgtgcgcg aagaaccttc ctcttttgcg tcatacggta cctgggcgcg gacggcggat
     7921 aaactggtgt taaccgacag caatggcgag aaatcgtatt atcgcgcgaa aggcaatgcg
     7981 ctggagatgc tcgacagaga aggcaatccg gtggcttcgc agcttaatta tacgctggtg
     8041 cctgttaccg ccagcctgcc ggtaacgcca atgccgctgc gtggtatgta tgtatacagg
     8101 gccgatgcgg cgacctttac cgattgcgcg accggaaaac ggctgccggt cgccagtaac
     8161 gcccagcttg agcgcggcta tctggcggcg aaaggtgaag cggaaaaacc ggtgctgctg
     8221 acggtcgaag ggcattttgt gtttgccgcg aatccggaca cgggcgagcc ggtaaaaacg
     8281 ctaatagctg ataaaaatgt gaagtttgcg ccgggtaaag attgcactca
//
LOCUS       DAJVKX010000167         8131 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.167, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000167 DAJVKX010000000
VERSION     DAJVKX010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8131
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.167"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(143..1267)
                     /locus_tag="OPY25_004040"
     CDS             complement(143..1267)
                     /locus_tag="OPY25_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0929510.1"
                     /translation="MPPLFTINACKSAGCRNLGLPDSPDYVWPDYRLGYPALHCRACG
                     SYPPLFNEGEFRRWASAYIAQYAKEHGHFCPDCYQRTWIRYGRNPGGTQRLQCQYCKK
                     VWTPKQHALNVAETPEQICSIPLLVPFQGANAFQQLYFLFSFDAVRGNILHLSSNFTL
                     LSAGKSLHYHWKGIAPPEGEKGDIIHRIAIKERQFLQRSQFDEIQYGPAALKRNAQGT
                     ILRPVITAHGHFRVLKNRFPDVATHIIAHECFLRGAVITAWAERFRQRLSSLWFVEEE
                     INDDDCRAEWQLLGKTWQGWWQNQWQLWGQGHNRKMVCSLTGSHLEQGVAVNLAASRR
                     FVTWLWQQPEFQQSAHCSAKRVTQILYLLTEKYNSQWNHI"
     gene            1403..2959
                     /locus_tag="OPY25_004041"
     CDS             1403..2959
                     /locus_tag="OPY25_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HCS0929511.1"
                     /translation="MKVKLLAAGILFTLPFWACAKDVTIIYTNDLHAHVEPYKVPWIA
                     DGKRDIGGWANITTLVKQEKAKNKATWFFDAGDYFTGPYISSLTKGKAIIDILNTMQY
                     DAATIGNHEFDHGWDNTLLQLSRAKFPIVQGNIFYEDSSKSFWDKPYTIVEKDGVKIG
                     VIGLHGVFAFNDTVSAATRVGIEARDEIKWLQRYIDELKGKVDLTVALIHEGTPARQS
                     SMGNTDVRRALDKDIQTASQVKGLDILITGHAHVGTPEPIKVGNTLILSTDSGGIDVG
                     KLVLDYQEKPHQFTVKNFELKTIFADEWKPDPQTKQVIDGWNKKLDKVVQQTVAQSPV
                     ELTRAYGESSSLGNLAADALLFTAGKDTQLALTNSGGIRNEIPAGAVTMGAVISTFPF
                     PNELVTMDLTGKQLRSLMEHGAGLSNGVLQVSKGLEMKYDSSKPIGQRVTVLTLNGKP
                     IDDAAVYHIATNSFLADGGDGFAAFTEGQARNTSGGYYVSNAIVDYFKAGNTITDEQL
                     KGMRVADVKK"
     gene            3224..4462
                     /locus_tag="OPY25_004042"
     CDS             3224..4462
                     /locus_tag="OPY25_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014341216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCS0929512.1"
                     /translation="MINNDPLFDLLNKEQQRQQHSLELIASENFASPAVLAAQGSVLT
                     NKYAEGYYQHRYYGGCKFIDEVEMLAITRAQQLFGARYVNVQPHSGSQANQAVYLALL
                     KPGDKILGMSLQCGGHLTHGSPVNQSGKWFNAFHYGVDAHSGLIDMDEVETIAKRERP
                     RLIIAGGSAYPRHYDFARFRRIADAVGAMLLVDMAHFAGLVAGGCFPSPLAYADVITA
                     TTHKTLRGPRGGMILTNDARLAKKIDSAIFPGLQGGPLMHVIAAKAVALGEALQPEFK
                     RYAGQVIENAQAMCQQLAQRGLTLLTGGTDCHLGIIDLRPQGLTGAQVEYFLELAGIT
                     VNKNTLLGDPQPPSITSGIRIGSAACATRGMKADDFTLIADWISEIIFAIKTPNIADI
                     CADIRQKVTKLTTNYPLPYQ"
     gene            4459..5565
                     /locus_tag="OPY25_004043"
     CDS             4459..5565
                     /locus_tag="OPY25_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase 3"
                     /protein_id="HCS0929513.1"
                     /translation="MMKLAEIQAACGVLCVDLAAVVDNYQTLARHVAPAQCGAVLKAN
                     GYGLGAEAIAPALYAANCRIFFVAQLSEGVALRNILSADAMVVLLNGVMPQAMPFCCA
                     QQITPLLNSVDQVMTWLALQEARSQRRPVLIQLDSGMSRLGVTPEQLARLAAIFRQRG
                     WAAPDYIISHLANADRPDHALNVYQHTLLQQAKKAFPTSRYSLANSCGMFLHPAWRED
                     LCRPGVALFGVAQPWFSTPLKPAFTLTLTILRVQDVPVGTPIGYGSTVTTTRPLRIAT
                     VSAGYADGIPRNLRPPAGVCWRGVRLPVLGRVCMDSFMVDASAIMPTSGDVVEFIGVS
                     QTLEEVAAACDTIPYEIMARLGARFRRIMQPAEA"
     gene            complement(5510..6991)
                     /locus_tag="OPY25_004044"
     CDS             complement(5510..6991)
                     /locus_tag="OPY25_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCS0929514.1"
                     /translation="MNTANFESIHIMIDAQAWRNLPLHLRLYHAFRQLVISGALADGA
                     KLPSARALAQRLHLSRDTVENAYSQLQRDGFMTRRQGAGSFASRQGVPHIQGQHSLPP
                     SPRQTPTLSARWQTIADRAVSFDARRVQTFTLGLAETRNFPQTIWQNFARQIQRERAH
                     TLMLHGDPQGEQELRQQIAHYLNFERGAKVDAQQIVIVSGARQAFWLCGQLLAEAGQS
                     VVMENPGYPGARQAFSAAQLNLLPIEVDGDGIRVDKLPPAPLVYVTPSHQFPSGHLLS
                     LARRHALIDWAQAHNAWIIEDDYDSEFHYNGAPVACMQGLDREQRTLYVGTFSKTLYP
                     GLRIGYLVVPASLAAHFAAARNLLDGATPALTQLTLARFIASGHFAAHIRTMRSMYAV
                     RQACLAQAINQHLSDWVTPVVTPGGLQMPCWLHEGIDEQQTLNAARRAGLNIAGMRQF
                     WLTHPAPTGWLLGFAAFTPYEIENGVKLLRAALCAENVRQAGP"
     gene            7270..>8131
                     /gene="metF"
                     /locus_tag="OPY25_004045"
     CDS             7270..>8131
                     /gene="metF"
                     /locus_tag="OPY25_004045"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HCS0929515.1"
                     /translation="MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPSWMSLMFEGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAIC"
BASE COUNT         1824 a         2115 c         2317 g         1875 t
ORIGIN      
        1 atcttaacgc aaaacgaagg gccatttatc aaatagctct attctttttc agcgtgtaaa
       61 agcaggatgt gaggtgatta aatctatagc gccttctgaa tgataatctg tgatttttta
      121 tgcgtggcat tacatcattg agttaaatgt gattccattg tgagttatat ttttccgtca
      181 gcaaatacag aatttgtgtg acgcgtttgg cggaacagtg ggcgctttgc tggaattcag
      241 gttgttgcca tagccaggta acaaagcggc gactggccgc cagattaacg gcgacacctt
      301 gttctaagtg ggaaccggtt aacgaacaga ccattttgcg gttgtgacct tgcccccaga
      361 gttgccactg attttgccac catccctgcc atgttttgcc taacagttgc cactctgcgc
      421 ggcaatcgtc atcgtttatc tcttcctcaa cgaaccacag cgaggagaga cgctggcgaa
      481 accgctccgc ccatgccgta atgaccgcgc cgcgcaaaaa acactcatgg gcaatgatgt
      541 gtgtcgcgac atcaggaaag cggtttttca gcacccgaaa atgaccatgc gccgtaatca
      601 ccgggcgaag tattgttcct tgcgcgttac gtttaagcgc cgccgggcca tactgaatct
      661 catcgaactg gctgcgctgt aaaaattgcc gttctttaat ggcgatacgg tgaataatat
      721 cgcccttctc gccctcgggc ggcgcaattc ctttccagtg gtaatgcaaa ctctttccgg
      781 cagaaagtaa cgtgaaattg ctggaaaggt gaagtatatt gccgcgaaca gcatcaaaac
      841 tgaataaaaa gtacaattgt tggaaggcat tcgctccctg aaacggtacg agcagcggaa
      901 tactgcaaat ctgttccggc gtttcggcga cattcagcgc gtgctgtttt ggcgtccaga
      961 ccttcttaca gtactggcac tgaagtcgct gcgttccgcc gggattacgt ccataacgaa
     1021 tccatgttct ttgatagcaa tcggggcaaa agtgaccatg ctctttggca tattgcgcga
     1081 tgtaagcaga cgcccagcgg cgaaattccc cctcgttgaa gagcggtgga taactgccgc
     1141 aggcccgaca atgcaatgcc ggataaccca ggcgatagtc cggccacaca taatccggcg
     1201 agtcaggcag cccaagattg cgacaaccag cgcttttgca ggcattaatg gtgaacagag
     1261 gcggcataca ttttaccaac gattttggca ggtcgttgat tctgccttca taaaacggta
     1321 cgcgggtgtg aggactctca cataaaaaaa cctttcagaa cgtaacgtag cgaatcttta
     1381 tatgactgaa agggacttat ttatgaaagt aaaactgctt gctgccggta ttttgttcac
     1441 gctgccgttc tgggcctgcg ccaaagatgt caccattatt tacaccaacg atctacacgc
     1501 ccatgtggag ccttataaag taccgtggat tgctgacggt aaacgcgata ttggcggttg
     1561 ggccaatatc actacgctgg tgaagcagga aaaagccaaa aataaggcga cgtggttttt
     1621 tgatgccgga gattacttta ccggaccgta tatcagcagc ctgacgaagg gtaaagcgat
     1681 tatcgatatt ttgaatacca tgcagtatga cgctgccact atcggtaatc atgagttcga
     1741 tcatggctgg gacaatacat tgttgcaact gagccgggcg aaattcccta tcgtacaggg
     1801 caatattttt tatgaggaca gcagtaaatc cttctgggat aagccgtaca ccattgttga
     1861 aaaagatggc gtcaagattg gcgtaatcgg cttacacggt gtctttgctt ttaatgatac
     1921 ggtttctgcc gcgacgcgcg tgggcattga ggctcgcgat gaaattaagt ggctgcaacg
     1981 ttacattgat gaacttaaag gtaaagtcga tctgaccgtc gcgctgatcc acgaaggcac
     2041 cccggcccgc cagtccagca tggggaatac cgatgtgcga cgcgcgctgg ataaagatat
     2101 tcagaccgca agtcaggtaa aagggctgga tattttgatt accggccacg cgcatgtcgg
     2161 tacgccggaa ccgattaaag tcggtaatac gctgatcctc tcaacggaca gcggcggtat
     2221 tgatgtcggc aaactggtgc tggactacca ggaaaagccg catcagttta ccgtgaagaa
     2281 cttcgagctg aagaccattt ttgctgatga gtggaagccc gatccgcaaa cgaaacaggt
     2341 gatcgacggc tggaacaaaa agctcgataa agtcgtgcag caaacggtgg cgcagtcgcc
     2401 ggttgagctg acccgcgcgt atggcgaatc gtcgtcgctg gggaatctgg cggcggatgc
     2461 gctgcttttt acggcgggga aagacaccca gttagcgctt actaactctg gcggtatccg
     2521 caacgaaatc ccggctggtg cggtgacgat gggggcggta atcagtacct tcccgttccc
     2581 taatgaactg gtcacgatgg atttaaccgg taaacaattg cgcagcctga tggagcatgg
     2641 cgccggatta agcaacggcg tgttgcaggt gtctaaaggg ctggagatga agtatgacag
     2701 cagcaaacct atcggccagc gggttaccgt gctgacgctc aatggcaagc cgattgatga
     2761 tgcggcggtt tatcacatcg ctaccaacag cttccttgcc gacggcggcg atggttttgc
     2821 ggcgttcacg gaaggccagg cacggaacac ctccggcggc tactatgtgt cgaatgcgat
     2881 agttgattac tttaaggcgg gcaacaccat cacggatgag cagctcaaag gaatgcgtgt
     2941 tgcggatgtg aagaagtaag gggttacttg cctgtgcgca atggccttta gcgcattcag
     3001 gccggacggc ggtatgtctg gcctggatca ttcgtggacc gcggatatca accgtctggc
     3061 gtagcttctg taattttgcc gggttacgcg ccgcgttccc ggcatgttcc tgccgaaatt
     3121 tacccctcta tccggtggtc tgcgtcctgc gtaaaaagtg gcggggtgcg ggggaaactt
     3181 tccctgcgaa aatcatcata tgatgaattt tcgggggaac cgcatgataa acaacgatcc
     3241 gctttttgat ttacttaata aagagcaaca gcgccagcag cactcgctgg aactgattgc
     3301 ctcggagaat ttcgccagcc ctgccgttct tgcggcacaa gggtcggtgt taaccaataa
     3361 atacgccgaa ggctattacc agcaccgcta ctacggcggc tgtaagttca ttgatgaggt
     3421 tgagatgctg gcgataaccc gcgcgcagca acttttcggc gcgcgttatg ttaacgtgca
     3481 gcctcactcc ggcagccagg cgaatcaggc ggtatatctg gcgctgctga aacccggcga
     3541 caaaattctg ggcatgagcc tgcaatgcgg cggccatctc actcacggct cgccggtcaa
     3601 tcaatccggc aaatggttta acgcctttca ctatggcgtc gatgcgcata gcggtcttat
     3661 tgatatggat gaggttgaga cgatcgcgaa gcgtgagcgc ccgcggctga ttatcgccgg
     3721 gggatcggcc tacccacgac actatgattt tgcccgcttt cgccgcattg ccgatgccgt
     3781 cggcgcgatg ctgctggtgg atatggcgca ttttgccggg ctggtggcgg gcggctgttt
     3841 cccctcgccg ctggcgtatg ccgatgtgat taccgccacc acgcataaaa cgttgcgcgg
     3901 gccgcgtggc ggcatgattc tgaccaacga cgcccggctg gcgaaaaaaa tcgacagcgc
     3961 catctttccc ggcttgcagg gcgggccgtt gatgcacgtt atcgcggcta aagcggtggc
     4021 gcttggcgaa gcgctacagc ctgaatttaa acgttacgcc gggcaggtaa tcgaaaatgc
     4081 gcaagcgatg tgccagcaac tggcgcagcg cggcctgacg ctgttaacgg gcggtaccga
     4141 ctgccatctg ggcattatcg acctgcgccc gcaggggtta accggcgctc aggtggaata
     4201 ctttctcgaa ctggcgggga tcacggtcaa taaaaacacg ttgctaggcg atccacagcc
     4261 gccgtcgatt acctccggga ttcgcattgg cagcgcagcc tgcgccaccc gcgggatgaa
     4321 ggccgatgat tttacgctga tcgcggactg gatcagtgaa attatttttg ccatcaagac
     4381 gccgaatatt gcagatattt gcgccgatat tcggcaaaaa gtgactaaat taaccaccaa
     4441 ctatccgttg ccttaccaat gatgaaactt gctgaaattc aggcggcgtg cggcgttctt
     4501 tgtgtagatc tcgccgctgt cgttgacaat tatcaaacgc tggcgcgcca tgtcgccccc
     4561 gcgcaatgcg gcgcagtact gaaagccaat ggctatggct tgggggcgga ggcgattgcg
     4621 ccagccctgt atgcggccaa ttgccggatc ttttttgtcg cgcaactttc tgaaggggtg
     4681 gcgctacgta acatcctgtc ggctgacgcg atggtggtgt tgcttaatgg cgtcatgccg
     4741 caggcgatgc cgttttgttg cgcgcaacag atcacaccat tgttgaattc cgttgaccag
     4801 gtgatgacgt ggctggcgtt acaggaggct cggtcgcagc ggcgtccggt cttgatccag
     4861 cttgactctg gtatgtcgcg gctgggggtg acgccggagc aactggcgcg gctggccgcg
     4921 atttttcgcc agcgtggctg ggctgcgcca gactatatca tcagccatct ggccaacgcc
     4981 gacaggccgg atcatgcgtt aaatgtctat cagcatacgc tactccagca ggcaaaaaag
     5041 gcattcccaa ccagccgtta ttcgctggca aattcctgcg gtatgtttct gcatccggcc
     5101 tggcgggaag atctttgccg tccgggcgtt gcgctgttcg gcgtcgccca gccgtggttt
     5161 tcaacgccgt taaaaccggc atttacgctg acgttgacca ttttgcgcgt gcaagacgtg
     5221 ccggttggga cgccgattgg ctacggcagt acggttacta ccactcgccc gctgcgtatc
     5281 gccacggtat ccgccggata cgctgatggg attccgcgta atttgcgtcc tccggcgggc
     5341 gtgtgctggc gcggggttcg gttgccggtg ttggggcggg tctgcatgga cagctttatg
     5401 gtggacgcca gcgccatcat gccaacgtct ggcgatgttg tggagtttat tggcgtgagc
     5461 cagacgctgg aagaggttgc tgccgcctgc gataccatcc cttatgagat tatggcccgg
     5521 cttggcgcac gttttcggcg cataatgcag cccgcagaag cttgactcca ttttcaatct
     5581 cgtagggggt aaacgcggcg aatcccaaca gccagcccgt gggcgcgggg tgcgtcagcc
     5641 agaactggcg catcccggcg atgtttaacc cggcccgccg cgcggcgtta agggtctgtt
     5701 gttcgtcaat accttcatgc agccagcagg gcatttgtaa tcctccgggc gtcactaccg
     5761 gcgtcaccca atcactaaga tgctggttga tggcctgcgc caggcacgcc tgccgcaccg
     5821 cgtacatact gcgcatggtg cggatatggg cggcaaaatg gccggatgcg ataaatcgcg
     5881 ccagcgtcaa ttgggtcaac gcgggcgttg cgccatcaag caaattacgc gcagcggcaa
     5941 agtgcgcggc cagcgacgca ggcaccacca gataaccaat gcgcagaccg gggtagagcg
     6001 ttttgctgaa ggtgccgaca tacagggtgc gctgctcgcg atctaacccc tgcatacagg
     6061 cgacgggcgc gccgttgtag tgaaattcac tgtcgtagtc atcttcgata atccaggcat
     6121 tatgcgcctg tgcccagtca atcagggcat gacgccgcgc cagagagagc aaatgaccgg
     6181 agggaaactg gtgcgacggc gtaacgtaaa ccagcggcgc aggcggcagt ttatccaccc
     6241 gaataccgtc tccatcgact tcaatgggaa gaaggttgag ctgtgcggca gagaatgcct
     6301 gacgcgcgcc gggatagcct ggattttcca tcaccaccga ctgcccggcc tctgccagca
     6361 gttgcccgca tagccagaat gcctgacgcg cgccactgac aatcacaatc tgctgcgcgt
     6421 cgaccttcgc gccgcgttca aaattgagat aatgggcaat ttgctggcgc agttcctgct
     6481 ctccctgcgg atcgccatgc agcattagcg tatgcgcccg ctcgcgctgg atctggcggg
     6541 caaaattctg ccaaatggtt tgcgggaagt ttcgcgtttc cgcaaggccg agcgtaaacg
     6601 tctgcacccg gcgggcatcg aaagatacgg cgcgatcggc aatcgtctgc cagcgggcgc
     6661 taagcgtggg cgtctggcga ggcgatggcg gcaggctgtg ctgcccctga atatgcggaa
     6721 ccccctggcg gctggcgaaa ctcccggccc cttgcctgcg ggtcataaag ccgtcgcgct
     6781 gaagctggga ataggcattt tcgacggtat ccctggaaag gtgcagccgc tgggccagcg
     6841 cgcgagcgga aggtagcttt gcgccatcag ccaacgcacc ggaaattacc aattggcgaa
     6901 aagcgtggta caggcgcaga tgcagcggta gattgcgcca cgcttgcgcg tcgatcatga
     6961 tatgtatcga ctcgaaattc gctgtgttca tcttctggtt cccccgtccc tgcgtcgcca
     7021 aagtcgttga atcatatcat ttacgcctta ttttttatgt gttgaagaac acccggaacc
     7081 gtatgaagaa ggtattgctc aagatgatgg agaatgaagt tttttcaact ttgctgaata
     7141 ttcctcattc tttggcgtga tttttcagtt gacgtccttc cgcttttccg tcatttttac
     7201 atctggacgt ctaaacggat agatgtttac agcacaacaa ataataacat gcgattgatg
     7261 aggtaaggta tgagcttttt tcacgccaac cagcgggaag ccctgaatca gagcctggcg
     7321 gaagtacagg gtcagattaa cgtttcgttt gaatttttcc cgccgcgcac cagtgaaatg
     7381 gagcaaaccc tgtggaactc catcgatcgc ctgagcagcc tgaaaccgaa gtttgtttcg
     7441 gtaacgtatg gcgccaactc cggggaacgt gaccgcactc atagtgttat taaaggcatt
     7501 aaagagcgta ctgggcttga ggccgcgccg caccttacct gtattgacgc cacgcgcgat
     7561 gaactgcgca ccatcgcccg cgactactgg aataacggta tccgccacat tgttgctttg
     7621 cgcggcgatt tgccgccggg cagcggtaag ccggagatgt acgccgccga tctggttggt
     7681 ttgctcaaag aggtggccga tttcgatatt tcagtagcgg cctatccgga ggtacatccg
     7741 gaagcgaaaa gcgcgcaggc cgatctgctt aatctgaagc gtaaagtgga tgctggcgct
     7801 aaccgcgcga taacccaatt tttcttcgat gtggaaagct atctgcgttt tcgcgaccgc
     7861 tgtgtttccg ccggtatcga cgtagaaatt attcccggca ttttaccggt gtctaacttt
     7921 aaacaggcga aaaaatttgc cgatatgacc aatgtccgca ttccgtcctg gatgtcgctg
     7981 atgtttgagg ggctggatga tgacgcagaa acccgcaagc tggtgggcgc taacattgcg
     8041 atggacatgg tgaaaatttt aagccgcgaa ggagtgaagg atttccactt ctacacgttg
     8101 aatcgtgcgg aaatgagtta tgccatttgc c
//
LOCUS       DAJVKX010000168         8095 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.168, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000168 DAJVKX010000000
VERSION     DAJVKX010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8095
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.168"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            490..813
                     /locus_tag="OPY25_004046"
     CDS             490..813
                     /locus_tag="OPY25_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929516.1"
                     /translation="MEALAIPVKLYIHYNANTFAQEKVIVSTCDMSRTFPDQYVLLET
                     RDISIDVNQPEPFDIIALQVDQLRGQKEKIATLAKHQIAQVDDKIQQLLCIDHSPVQE
                     SDIPS"
     gene            821..1066
                     /locus_tag="OPY25_004047"
     CDS             821..1066
                     /locus_tag="OPY25_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929517.1"
                     /translation="MQTEIIIDKVMSAGLSVLEHENNGDFGNGVMHLTIVGGVRRVEF
                     YPTTGTVYANAVKGKYPVFKQKKAGIKIAIRLAKSGA"
     gene            1096..3336
                     /locus_tag="OPY25_004048"
     CDS             1096..3336
                     /locus_tag="OPY25_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929518.1"
                     /translation="MTIYNCLFEPKKSAIKDGAVALAISIEAPNKKVAESIVIGKLWE
                     HFPANGDNYFRPKIWEDSEGQPRPEVGKFDEQFAQANTFDGEKWIANKPDTSVPGLPS
                     SDEIIDLMKLPARERFATVLMFSDSPIDGVLYSQVLDYLDNLENNTEPFDDDDRINSN
                     ILHALHNNEPVRHMHVEGLNNLIQAIFAKFEDQTPGKAAISQFIKRWLENPGKREEMV
                     PSKTSSLNTSDHIKGPKVAPLRGYKHTYATLDQEIAVALLPISPDTPVLSGNLRDAEK
                     IIAEDREDFKRWSMALRTTEKILRYDRPSIFGVIQNTPAKDTYHFPESLRRHIDSWLT
                     EHGQFECPESDAERTGKLLSDPNDPKWVKTDTQPQVSNLGNGMFSVDNLMSETASNEG
                     EKTEVAEQETVTEDQAEQARETLNNMGYGVYATSQDTTDQQNENLSDKVEKIVQDADQ
                     LVDRVKREEQLPQASELVKSINEMQAGESDNLELWKDVFKTDERFTTAFSVNGGGTSI
                     NGTYMTMIATREFGPKGIGWGVDILEERFDNGAPITRTVKGTDGNNTWELIPDGVGGI
                     LTEKHHIIKIRLWYIRNGVRGEEISFGCTPYIYSSKHGLICDGEATKKSLTDATKKAL
                     SALGFCADIFMGLYDNQEYRQKNKAEFALKNASENAEDAARVRQELDDKLTRVANTLA
                     SAVSENEINKVYSSIAREAEVHRKDAEAKGDTQHARYLGGRLRRLTTIKDERIAELNK
                     AQEKAE"
     gene            3333..3887
                     /locus_tag="OPY25_004049"
     CDS             3333..3887
                     /locus_tag="OPY25_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HCS0929519.1"
                     /translation="MTTAIALAADYTSLLQLLESSDELTPEMIADTLESIKGELDDKL
                     DAIMVIARNNLGHAKTCDEEIKRLAERKKHFENKDKALRKYILSCLMTANLDKLKTSK
                     NTFSVRKGSISVVIDNEKLLPDELVTVQTIIAPDKKAIKEAIEAAEAAAAQITADGGE
                     VPAELLNPVPGAHLEIGERSLQVR"
     gene            3890..4072
                     /locus_tag="OPY25_004050"
     CDS             3890..4072
                     /locus_tag="OPY25_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929520.1"
                     /translation="MLKLSLKRGDAVHVVFADGSNGIIEARSRCELGMHLPKNVKVTR
                     EKGAFLPENLIKRNQK"
     gene            4285..4509
                     /locus_tag="OPY25_004051"
     CDS             4285..4509
                     /locus_tag="OPY25_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007374199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4224 domain-containing protein"
                     /protein_id="HCS0929521.1"
                     /translation="MTRENDLLTDAELIEFTGYQKPSKQREILDRGGVSYIPDREGRP
                     MVTWTHINAVLNGQIIVQQSTETKPDFGAI"
     gene            4510..5529
                     /locus_tag="OPY25_004052"
     CDS             4510..5529
                     /locus_tag="OPY25_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016152503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCS0929522.1"
                     /translation="MGRRRKDLGDVKLPPRVSKTRTRYYYKPTSRETVTLGPITLTMS
                     ALWKRYEEERRNYSDVMTFEKLWGMFLKSAYYTELAIRTQRDYLQHQKKLLAVFGKVK
                     ADVIKPEDVRQFMDRRGLQSKNQANQEMSSMSRVYRWGYERGYVKGNPCAGVSKFSLK
                     AREQYITDEDYLAIYKHADHVVRAAMEISYLCAARQADVLALRWMQVSDKGIFIQQGK
                     TGKKQIKVWTPRLQQALKTAQTECPKLSPDALVLYNNDRGQFIRKTFNNRWLKAVRAA
                     QSELGRQLDYTFHDIKAKAISDFEGSSRDKQIFSGHKTESQVLIYDRKVQISPTLDRP
                     IIGEK"
     gene            complement(5635..5722)
                     /locus_tag="OPY25_004053"
     tRNA            complement(5635..5722)
                     /locus_tag="OPY25_004053"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5686..5688),aa:Ser,seq:tga)
     gene            6117..6776
                     /gene="yccA"
                     /locus_tag="OPY25_004054"
     CDS             6117..6776
                     /gene="yccA"
                     /locus_tag="OPY25_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HCS0929523.1"
                     /translation="MDRIITSSRDRSSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPVGILSAFAFTGFLGYILGPILNAYLSAGM
                     GDVIGLALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILYETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            6863..7192
                     /gene="tusE"
                     /locus_tag="OPY25_004055"
     CDS             6863..7192
                     /gene="tusE"
                     /locus_tag="OPY25_004055"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HCS0929524.1"
                     /translation="MLIFEGKEISTDSEGYLKETTQWSEALAVAIAANEGIELSAEHW
                     EVVRFVREFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(7189..7470)
                     /gene="yccX"
                     /locus_tag="OPY25_004056"
     CDS             complement(7189..7470)
                     /gene="yccX"
                     /locus_tag="OPY25_004056"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCS0929525.1"
                     /translation="MSNVCIIAWVYGRVQGVGFRYTTQHEAQRLGLTGYAKNMDDGSV
                     EVVACGDAAQVEKLIKWLKEGGPRSARVDKILTEPHSPRETLTGFSIRY"
     gene            complement(7519..>8095)
                     /locus_tag="OPY25_004057"
     CDS             complement(7519..>8095)
                     /locus_tag="OPY25_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929526.1"
                     /translation="QPAQNGFRSDLLLLSPEIIARFKTMYVQDYPPANLTSLCTPMSR
                     SLTFMWENVLDAVRQGLPVGLQEHQAMGLLLALLHDGAAGPLLIERRYTLTEQVRQLI
                     MLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALSQLQSTTLPI
                     GEIALRCGYLSGSRFTARFRQHYGCLPSQVR"
BASE COUNT         2258 a         2016 c         1991 g         1830 t
ORIGIN      
        1 acaaattcgc gggtcgccgc cagtacgatg acatgcggga aagaccgcaa ctggattcga
       61 ttcgttgcag tggtggaagg taagagcaat gggtgcgtaa cgccacacaa gccccctgtc
      121 acggcagtga acgcggttga gccgtccgcc cgcgtaaaga acgccccgtg aggcttaaaa
      181 acaggccgta tgatccacgt tacggatcat caaatatcca ttgctgtgtg tagtctttgc
      241 ctcgtctcaa tgaggggcaa ttttttacac agcaaccagt accgaggaaa gacctggcgg
      301 gtatgaccag ccctgacagc ccggaaagac gggcaacaga tgtaaaaaaa cccaccgaag
      361 tgggtttctt tacccggaac ggcgaccaaa ccactccgga ggtggtacag gggaccaacc
      421 ctgcaccgag gaaagaccaa cgacatgagc cgctgatcgg ctcggattat acactagtaa
      481 ggagccgcta tggaagcgct tgccatccca gtaaagctgt acatccatta caacgccaac
      541 acgtttgctc aggaaaaagt catcgtatct acctgtgaca tgtcacgcac ctttccagat
      601 caatacgtcc tgctggagac tcgcgatata tccatcgatg taaaccagcc agaacctttc
      661 gacatcattg ctcttcaggt cgaccagttg cgtggtcaga aagagaagat agcaacgctg
      721 gcaaaacatc agatagccca ggttgacgac aaaatacagc aactgctgtg tattgatcac
      781 tctcctgtcc aggaaagcga tattccgtcc tgaggtaacc atgcagactg aaattatcat
      841 cgacaaggta atgagtgctg gcttgtctgt acttgaacat gagaacaacg gcgatttcgg
      901 aaatggcgtt atgcatctaa caattgtcgg tggtgttcgc cgcgttgaat tctatccaac
      961 aaccggaact gtgtacgcta acgccgtaaa aggtaagtac ccggttttta agcagaagaa
     1021 agcaggaatc aaaatagcta tccgacttgc aaaatcaggc gcctgaccag cgccaggaac
     1081 caaagaggaa agaccatgac aatttacaac tgtctgttcg agccgaagaa atcggctatt
     1141 aaagatggtg ctgttgctct ggcaatcagc atcgaagcac caaataaaaa agtcgctgaa
     1201 agtatcgtca ttggcaaact ctgggaacac ttcccggcaa acggcgacaa ctattttagg
     1261 ccaaaaatct gggaagactc ggagggccag cctcgtccgg aagttggaaa atttgatgaa
     1321 caatttgctc aggcgaatac ttttgacggg gaaaaatgga tcgccaacaa accagacacc
     1381 agcgttccag gtttaccaag cagtgatgaa atcatcgatc tgatgaagct gccagcccgg
     1441 gaacggttcg ctaccgtcct catgttcagc gattctccca tagatggtgt gctttattct
     1501 caggttctgg actatctcga taatctggaa aataacactg aaccctttga tgatgacgat
     1561 cggattaatt caaatatcct tcatgcactg cacaataacg agcccgttcg tcatatgcat
     1621 gttgaagggt taaacaatct tattcaggcc atcttcgcta aatttgaaga ccagacaccg
     1681 ggcaaggctg ctatttcgca atttatcaaa cgctggctgg agaatccggg taagcgtgaa
     1741 gaaatggtac ctagcaagac atcttcactt aacaccagcg atcatataaa gggtcctaaa
     1801 gtagcccccc tacgcggtta taagcacact tacgcaacac tggaccagga gatcgccgtc
     1861 gccctgctac ctatatctcc tgacacacct gtgctttcag gaaatcttcg cgatgcggaa
     1921 aaaatcattg cagaagaccg ggaggatttt aaacgctggt caatggccct gcgtaccact
     1981 gagaagatcc tcagatatga ccgaccgagt atttttggcg ttatacagaa cacgccagcc
     2041 aaagatactt accatttccc tgagtctctt cggcgccata ttgattcatg gctgactgag
     2101 catggtcagt tcgaatgtcc tgaatccgat gcggagagga ccggtaagct gctcagtgac
     2161 cctaacgatc cgaaatgggt taaaaccgat acccaaccac aggtatcaaa cctcggcaat
     2221 ggaatgttct ccgttgataa tctgatgtct gaaaccgcct caaatgaagg tgaaaaaacg
     2281 gaagtggcag aacaggaaac agttacagaa gaccaggcgg agcaggctcg tgaaacgcta
     2341 aataatatgg gttacggagt atatgcaacc agccaggaca caactgacca acagaatgaa
     2401 aatctgagcg ataaagtgga aaaaattgtt caggatgcgg atcagctcgt cgatcgcgtt
     2461 aagcgtgaag aacagctccc tcaggcgtca gaactggtta agagcattaa tgaaatgcag
     2521 gctggagaaa gcgacaacct ggaattgtgg aaagacgtgt tcaaaacaga cgagcgtttt
     2581 actactgcgt tctctgtgaa cggaggcgga acctcaatca atggtaccta catgaccatg
     2641 atcgctacac gcgaatttgg tccaaaaggt atcggctggg gtgtcgatat tctggaagag
     2701 cgctttgaca atggcgcgcc aattactcgc acagtcaaag gcactgacgg taacaacacg
     2761 tgggaactca tccccgacgg tgtcggcggc atcctgacag aaaaacatca cattatcaaa
     2821 atcagacttt ggtacatccg caacggtgta cgcggtgagg agatttcttt cgggtgtacc
     2881 ccatatatct acagcagcaa acatggcctt atttgtgatg gtgaagcgac aaaaaaatca
     2941 ctgactgacg caaccaaaaa agcgctgtct gcgcttggtt tctgcgctga tattttcatg
     3001 ggcctgtacg acaaccagga gtatcgccag aaaaataaag ctgaattcgc gctcaaaaac
     3061 gccagcgaaa acgcggaaga tgcagcccgc gttcgtcagg aactggacga caaactgacc
     3121 cgagtcgcaa acacccttgc atcagctgtg tcagagaacg agatcaacaa ggtttattct
     3181 tcgattgccc gcgaagcgga agtgcatcgc aaggatgcag aggcgaaagg tgatacacag
     3241 cacgcgcgtt acttaggtgg gcgtctgcgg cggctgacaa ccattaaaga tgaacgtatc
     3301 gccgaactga acaaagcgca ggagaaagca gaatgactac tgcaatcgcg ttagctgccg
     3361 actataccag tctgctgcaa ttgctggaaa gctctgatga actgactccg gaaatgatcg
     3421 ccgatacgct ggaaagcatt aagggtgaac tcgatgataa gctggatgcc atcatggtaa
     3481 tcgcccgcaa taatctcggt catgctaaaa cctgcgatga agaaataaag cgcctggcgg
     3541 aacgtaaaaa gcatttcgaa aataaagata aagcattacg taaatatatt ctgtcgtgcc
     3601 tgatgaccgc taatctggat aagctcaaga cgtctaaaaa taccttttcc gtcagaaaag
     3661 gtagcatcag tgttgtcatc gataacgaga agctactgcc agacgaactg gttactgttc
     3721 agacgattat cgccccggac aaaaaagcca tcaaagaagc gatcgaagct gcggaagctg
     3781 ccgcagcgca aatcactgct gacggtggag aagtacctgc cgaactgtta aatccggtac
     3841 cgggcgccca tcttgagatc ggcgaacgct cactacaggt acgctaacaa tgctgaaact
     3901 atcacttaaa cgcggcgatg ccgtccacgt cgtattcgcg gacggtagta acgggattat
     3961 tgaagcacgc agccgttgtg aactgggtat gcacctgcca aaaaatgtaa aggttacgcg
     4021 cgagaaaggc gcattcctcc ccgaaaacct gattaagcgt aatcagaaat aaaccgccgg
     4081 caccgctagc attgtggtct cactatttac aggagaccgc aatgctgcga tggcaacccg
     4141 gagctaccct actcacagat ttcgatataa agattggccg gttatcggca agcgtacgaa
     4201 agaagacact gacccagtca gacatcgaac gcgcctgcag tgatgctgac gacgccgtgt
     4261 accggatgat gaggaaagac caacatgacc agagaaaacg atctgctaac agacgctgaa
     4321 cttattgaat ttaccggtta tcagaaacca tccaaacaac gggaaatact ggaccgtggc
     4381 ggcgtttctt acattcccga tcgggagggg cgccccatgg taacctggac tcatatcaac
     4441 gctgtactga acggacagat catcgtgcag caatctacag aaacaaaacc cgatttcgga
     4501 gcaatttaaa tggggcgcag aagaaaagat ctgggcgatg tcaagctccc cccacgcgta
     4561 tcaaaaacca gaacccgtta ctactacaaa cccacgtcgc gggaaactgt gacactgggg
     4621 ccaatcactc tcactatgtc ggcattatgg aaacggtacg aggaagaacg gcgcaattac
     4681 tcggatgtaa tgacgttcga aaagctctgg ggaatgtttc ttaaaagcgc ctactacacc
     4741 gagcttgcaa tacgaaccca gcgggattat ttgcaacatc agaaaaaatt gcttgccgtg
     4801 tttggtaaag ttaaagctga tgtaataaag ccagaagatg tgcgtcagtt tatggatcgt
     4861 cgtggactgc aaagtaaaaa ccaggctaac caggagatga gcagcatgtc acgtgtttac
     4921 cgctgggggt atgaacgcgg ttacgttaag ggaaatccgt gtgccggcgt cagtaaattc
     4981 tctctcaagg ctcgcgagca atacatcact gacgaagact acctggctat ttataagcat
     5041 gctgatcacg ttgtcagggc agcaatggaa atttcttacc tgtgcgccgc caggcaagct
     5101 gacgtactcg ctctgcgctg gatgcaagtt tctgataagg ggatttttat ccagcaagga
     5161 aagaccggaa aaaaacagat taaggtctgg acacctcgcc ttcagcaagc gctgaaaaca
     5221 gcacagacag aatgtccaaa actgtcacct gacgcgctgg ttctctacaa caacgatcgt
     5281 ggtcagttca tccgcaagac gttcaataat cgctggttaa aagctgtacg cgccgcacaa
     5341 agtgaactgg gccgacaact ggattacaca ttccacgata tcaaggcaaa agctatttca
     5401 gattttgagg gtagtagcag ggataagcag attttcagcg gccacaaaac agaaagccag
     5461 gtgcttatct acgacaggaa ggtacaaatc agcccgacac tggatcgtcc gattattggg
     5521 gaaaagtgaa tttttattca aatggaaaga tacgatattc tctgagaata ttcttttttt
     5581 attcttcgcc tcaaaaacga aggggctagc ttattgctaa ccccttgttt aatctggcgg
     5641 aagcgcagag attcgaactc tggaaccctt tcgggtcgcc ggttttcaag accggtgcct
     5701 tcaaccgctc ggccacactt ccagaatgag gcgcactata aacatcccgg tgcgtcatgt
     5761 aaagaccgaa tgtgttcgtt tgcgtgaaaa acaggcaaat tttcgttaat tgcctgaaat
     5821 agcggcacat tgaccatttc ttcaacacaa aaacgggctg aatacgtgtt gatcgtcccc
     5881 actgttttac ctctgtgatt atcaattttt tatcggtaac gcgtggttgg cgctgccgcc
     5941 tgttttatgg cgtagcgcca ggcatgagca gaccgtttta acgacggtaa tcacctgaaa
     6001 tctcttaagg aaactaaacg taaacgaatg cgtaaagatg ggtaaaacca ctgggtgaca
     6061 gtgactgttt ttattattct cctttattaa ttacatctgt cataagagag tgactaatgg
     6121 atcgtatcat tacatcatcg cgtgatcgta gctcgctact gagtacgcac aaagtactgc
     6181 gcaacaccta ttttctgttg agcctgacgc tggctttctc cgcaattacc gcgacagcca
     6241 gtacggtact gatgctgccc tcccccggcc tgattctgac gctggtcggt atgtatgggc
     6301 tgatgttcct gacctataaa accgccaata agccggtcgg tatcctgtct gcttttgcgt
     6361 ttaccggctt cctcggctat atcctgggcc cgattcttaa cgcctatctg tcagcaggca
     6421 tgggcgatgt gattggcctg gcgctgggtg gtaccgcgtt agtatttttc tgctgctccg
     6481 cttacgttct gaccacccgt aaggatatgt ctttcctggg cggtatgcta atggccggga
     6541 tcgtcgtcgt gctgattggt atggtggcga atattttcct gcaactgcct gcattgcacc
     6601 tggcgattag cgcggtgttt atcctgattt cctcgggcgc tatcctgtat gaaaccagta
     6661 acatcattca cggcggtgaa accaactata ttcgtgcgac cgtcagtctg tacgtttcgc
     6721 tgtacaacat ctttgtcagc ctgctcagca ttctgggctt cgccagccgc gactaatcga
     6781 cattcccctc ttccagccct gcttatgcag ggctttattt tttgctacac tgccgtccgt
     6841 gttgattacg cagtgaaacg ttatgttgat ctttgaaggt aaagaaatca gtactgatag
     6901 cgaaggctat ctgaaagaga cgacgcagtg gagtgaagcg ctggcagtcg ctatcgccgc
     6961 caatgaaggc attgagctct ctgcggaaca ctgggaagtc gtgcgcttcg tgcgcgaatt
     7021 ttacctggag tttaatacct ctcccgccat ccgaatgctg gtaaaagcga tggcgaataa
     7081 gttcggcgaa gaaaaaggca acagccgcta tctgtatcgt ctgttcccga aaggcccggc
     7141 aaagcaagcg accaaaatcg ccggtctgcc caagccggta aaatgtattt aataccgaat
     7201 actaaatcct gttagcgtct cgcgagggct gtgcggttca gtgaggattt tgtccacacg
     7261 agcagagcgc ggtccgcctt ctttcagcca cttgatgagc ttttctacct gcgccgcgtc
     7321 gccacaggcc accacttcta cgcttccgtc atccatattc ttcgcatagc cggttaaccc
     7381 cagccgctgc gcctcatgct gcgtggtata gcgaaacccg acgccctgaa cgcgaccata
     7441 aacccaggcg ataatgcaga cgttcgacat gatggttctc ctttcataat caacggtgaa
     7501 gacgcataca ggacatactt aacgtacctg actgggcaga cacccataat gttggcggaa
     7561 tctggccgta aatcgcgacc ccgacaggta gccgcaccgt agcgctattt cgccgatcgg
     7621 cagcgtcgtc gattgcagtt gagaaagcgc gcaggacatg cgtacctctt caataatttg
     7681 ccgataactc tgcgattcgc gctgcaaacg ccgacgcagc gtcgatgttc ccatagcaag
     7741 gcggcgggct atctcctggg ctgtccatag cttagcaggt gagagcataa tcagttgccg
     7801 cacctgctcc gtgagggtgt aacgccgttc aataagcagc ggtcccgccg cgccatcatg
     7861 taaaagcgct aacagtaacc ccatcgcctg atgttcctgt agcccaacgg gcaacccctg
     7921 gcgcacagca tccaacacgt tctcccacat aaatgtcagg ctacggctca tcggcgtaca
     7981 cagcgatgtc aggtttgccg gtggataatc ctgaacatac atcgttttaa agcgagcaat
     8041 aatctccggt gaaagtaaca acaggtcgga gcgaaaaccg ttctgcgcag gctga
//
LOCUS       DAJVKX010000169         7922 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.169, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000169 DAJVKX010000000
VERSION     DAJVKX010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7922
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.169"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(112..1509)
                     /gene="narK"
                     /locus_tag="OPY25_004058"
     CDS             complement(112..1509)
                     /gene="narK"
                     /locus_tag="OPY25_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HCS0929527.1"
                     /translation="MSHSSAPERATGAVITEWRPEDPAFWQQRGHRVASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPLFGGR
                     RWTAFSTGILIVPCVWLGFAVQDTSTPFSTFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAAFGSHGVEQPDGSQLYLANAAWI
                     WVPFLAIFTLAAWFGMNELATSKASLKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILHYAFFGPFIGALARSAGGAISDRLGGTRVTLINFVLMAIFSGL
                     LFLTLPTGGVGGSFIAFYGVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKNKK"
     gene            1849..3645
                     /gene="narX"
                     /locus_tag="OPY25_004059"
     CDS             1849..3645
                     /gene="narX"
                     /locus_tag="OPY25_004059"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HCS0929528.1"
                     /translation="MFKRCFSPLTLVNQLALIVMLSTAIGVAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLDAKDQKLLDEMEQTAFSPELTRAAERDGQQKQLKAL
                     QDYWHNELSPGLQHAQNAHAVAEDITRFVAGLDRLVTSFDHTTELRIERVVLVHRVMA
                     IFMALLLVFTIIWLRVRLLQPWKQLLSMARAVSQRDFTQRANISGRNEMAALGSALNN
                     MSEELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSQAPLCERLSPVLNGLQ
                     NLTQLHDIELRVYDLEDEDNHQEFTCQSDISCDDKGCHLCPRSALPMINGGTTLKWRL
                     TDSHTQYGILLATLPYGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQRLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNCSWAQLRELLT
                     TFRLQLTEPGLRPALEASCQEFSARFGFTVKLDYQLPPRLVPSHQAIHLLQIAREAPS
                     NALKHSHADDVVVTVTQCGKQVKLKVQDNGCGVPENAERSNHYGMIIMRDRAQSLRGD
                     CQVRRRETGGTEVTVTFIPETNFTETQGDTHE"
     gene            3638..4288
                     /gene="narL"
                     /locus_tag="OPY25_004060"
     CDS             3638..4288
                     /gene="narL"
                     /locus_tag="OPY25_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HCS0929529.1"
                     /translation="MNNQEPATILLIDDHPMLRTGVKQLVSMAPDISVVGEASNGEQG
                     IDLAESLDPDLILLDLNMPGMNGLETLDKLREKALSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDIEPEDLLKALQQAAAGEMVLSEALTPVLAASLRANRATTDRDVTQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWMHQERIF"
     gene            complement(4289..5713)
                     /locus_tag="OPY25_004061"
     CDS             complement(4289..5713)
                     /locus_tag="OPY25_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460724.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchO/YchP family invasin"
                     /protein_id="HCS0929530.1"
                     /translation="MPFLLSFVVEVADTLSRIVFRSFSLSLLLLAASGTIRAQAQDPF
                     DQNRLPDLGMMPESHEGEKHFAEMAKAFSEASMKNNDLDTGEQARQFAFGQVRDVVSE
                     QVNQQLESWLSAWGSASVDINVDNEGHFNGSRGSWFIPLQDKQRYLTWSQLGLTQQTD
                     GLVSNVGIGQRWAQDGWLLGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANYYQPFA
                     DWQTHTATLEQRMARGYDINAQVRLPFYQHINTSVSLEQYFGDSVDLFDSGTGYHNPV
                     ALKLGLNYTPVPLLTMTAQHKQGESGVSQNNLGLTLNYRFGVPLKKQLAASEVAQSQS
                     LRGSRYDTPQRNSLPTMEYRQRKTLTVFLATPPWDLTPGETVALKLQVRSVHGIRHLS
                     WQGDTQALSLTAGTDTRSTEGWTIIMPAWDHREGAANRWRLSVVVEDEKGQRVSSNEI
                     TLALTEPFITMPDDNPHWQPFQEQ"
     gene            5890..6243
                     /locus_tag="OPY25_004062"
     CDS             5890..6243
                     /locus_tag="OPY25_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/DsrF/TusD sulfur relay family protein"
                     /protein_id="HCS0929531.1"
                     /translation="MQNIVIIANGAAYGSESLFNSLRLAIALREQESHLDLRLFLMSD
                     AVTAGLRGQKPAEGYNIQQMLEILTAQNVPVKLCKTCADGRGITPLPLIDGVEIGTLV
                     ELAQWTLAADKVLTF"
     gene            complement(6323..6553)
                     /gene="chaB"
                     /locus_tag="OPY25_004063"
     CDS             complement(6323..6553)
                     /gene="chaB"
                     /locus_tag="OPY25_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HCS0929532.1"
                     /translation="MPYKAKSDLPDNVRNVLPAHAQDIYKEAFNSAWEQYKDKADRRD
                     DASREETAHKVAWAAVKNDYEKGEDDKWHKKK"
     gene            6820..7920
                     /gene="chaA"
                     /locus_tag="OPY25_004064"
     CDS             6820..7920
                     /gene="chaA"
                     /locus_tag="OPY25_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HCS0929533.1"
                     /translation="MTHACEAVKTRHKETSLIFPVLALVVLFLWGSSQSLPVVIGINI
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPQANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFIYEHEDEGDDDNPHHGKPSAH
                     SSGWHTVWLLIHLIAVIAVTKMNASPLEALLTSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAWATGNDLVFGLGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAYLALFAAYLMTIFA"
BASE COUNT         1961 a         2088 c         2018 g         1855 t
ORIGIN      
        1 aaatgtgcgt ggtcagccct gtcgcgcctc tcttcttgac tataagtatg ttgtaactaa
       61 atgcgggtaa aaaaaagcgc ggtctaacgc cgcgcaaagg ataatcaaaa gttacttttt
      121 atttttagaa tgacgtccat ataccgccca ggtaataacg acgcaggcga tatagaaaat
      181 aagaaagact ttcatcgcgc cgactggcga accggttaat gctaaagatg aaccaaacgc
      241 tttcggaata aaaaagccgc caatcgcgcc aatcgcggaa ataaagccca gcgccgccgc
      301 cgtatcggtc gccgcttcac gcatggctct ttcgtccgac ccgccttccg cttttacccg
      361 gtccatcgtc agtttacgga agataacgga gatcatctgg aaggtagaac cactccccag
      421 ccccgccgtc aggaatagcg ccagaaatac cccgtagaat gcgataaagc taccgccaac
      481 gccgccagta ggtaatgtca ggaacagcag accgctgaaa atcgccatca ggacaaagtt
      541 gataagcgtg acgcgagtcc cccccagacg gtcagaaatt gcgccgcctg ccgaacgcgc
      601 cagcgcgccg ataaacggac cgaaaaacgc ataatgcagg atctgcacat ccgggaattg
      661 cgttttagac agcatagcga accccgcgga gaaaccgata aacgatccga aggtcgccag
      721 atacagcaga ctcatgatcc acagatgacc acgtttgagc accggcagtt gctcttttag
      781 cgaggcctta gacgtcgcca gttcgttcat gccgaaccac gctgccagcg taaaaatggc
      841 caggaaaggc acccaaatcc aggctgcgtt cgccagatag agctgagaac cgtccggctg
      901 ctctacaccg tggctgccaa aggcggcaaa gatagagagc gaaaccacca gcggcgcaac
      961 cagctgcatc acgctcacgc ccatattgcc cagaccgccg ttcagaccca gcgcgccgcc
     1021 ctgcttttgt ttaggaaaga aaaagctgat gttcgccata ctggaggcaa agttcgcgcc
     1081 ggcaaaacca cacagcaagg aaataataat gaaagtgcta aatggcgtac tggtatcctg
     1141 aacggcaaag cctaaccata cgcaaggcac gatgaggata ccggtactga acgctgtcca
     1201 gcgacgtccg ccaaatagcg gcaccataaa ggagtaaggc acccgtagca gcgcgccgga
     1261 aacagatggc agcgcagtca acataaagag ctgatcggtc gtaaaattaa atcccacttt
     1321 cggcaggttc accgccactg cgctgaatag catccagacg caaaacgcca gcagtaaaca
     1381 cgggacagaa atccacaaat tacggctagc gacacgatgg ccgcgctgct gccagaacgc
     1441 cggatcttcc ggacgccatt ccgtgataac agcgccagtt gccctttccg gggcggatga
     1501 gtgactcata gacacctctg attcttgatt tgatgtctgc cacattaggg tttactgccg
     1561 aaggtaagtt gatataaatc aaaggaaaag tcgtcatcac cggcgactaa aaatagttat
     1621 tacccttaat gagtaggcta ttttggtaaa aaagctgtgg tttttcacca tgctgtgtct
     1681 gtctactcct tcccgtcgca gatacctctt tacggcggca attaaggagt aactcgttat
     1741 aggtatgggt atactccgct gtatcgttga gaatagcggc acagccgatt gacgccccct
     1801 tttttgctac gttttttcgg cgacattacc ccgaagaaag aaggtaacat gtttaaacgg
     1861 tgtttctctc ctcttacgct ggttaaccaa ctggcgctga ttgtcatgct ctctaccgct
     1921 atcggcgtgg cggggatggc ggtttccggc tggctggttc agggcgtgca gggtagcgct
     1981 catgcgatta ataaagcggg ctcattgcgt atgcaaagct atcgactact ggccgctgtc
     2041 ccgctggatg ctaaagatca aaagctgctg gatgagatgg agcaaacggc attcagccct
     2101 gaactgaccc gcgccgctga gcgagacggg cagcagaagc agcttaaagc gttgcaggat
     2161 tactggcata acgaactctc gccagggcta cagcacgcgc aaaacgcgca cgcggtcgca
     2221 gaagatatca cgcgctttgt ggcgggcctg gatcgcctgg tgacgtcgtt cgaccatacg
     2281 actgaattgc gtatcgaacg agtggtatta gttcaccggg taatggcgat ctttatggcg
     2341 ctattgctgg tatttacgat tatctggcta cgtgttcgcc ttttgcagcc ctggaaacag
     2401 ttgttatcaa tggcgcgcgc cgtcagtcag cgcgacttta cccaacgtgc caatatcagt
     2461 ggacgcaatg agatggccgc gttgggttct gcgctcaata atatgtctga agaactggcc
     2521 gaaagttatg cagtactgga acagcgagta caggaaaaaa cagccggtct ggaacataaa
     2581 aaccagattc tctcgttttt gtggcaagcc aaccgccgac tgcattcaca ggctccgcta
     2641 tgtgaacgtc tttcaccggt actgaatggc ctgcaaaatt taacccagtt gcatgatatt
     2701 gagctgcgag tctatgacct ggaagatgaa gataatcacc aggaatttac ctgtcagtcg
     2761 gacatcagtt gcgatgataa aggctgccac ctttgcccac gtagcgccct gccgatgatt
     2821 aacggcggca ccaccttaaa atggcggctc accgactctc acacccaata cggtattttg
     2881 ctggcgacgc tgccctatgg acgccatctc agccacgatc agcaacagtt ggtggacacg
     2941 ctggttgaac agcttaccgc gactctggcg ctcgacaggc atcaggagcg ccagcagcgg
     3001 ttgattgtca tggaagagcg tgccaccatt gcccgcgaac tgcatgattc tattgcccag
     3061 tcgctctctt gtatgaagat gcaggtgagc tgcctgcaaa tgcagggcga cgcgttaccg
     3121 gaaagcagcc gtgagttact cagccaaatt cgcaatgagc tgaactgctc ctgggcgcaa
     3181 ctgcgcgaac tgttaaccac tttccgctta cagttgacgg aacccgggct acgtccggcg
     3241 ctggaggcaa gctgccagga gttcagcgcc cggtttggct ttacggtaaa actggattat
     3301 cagcttcccc cccgcctggt gccatcacac caggcgatac acctgttgca aattgccagg
     3361 gaagccccca gcaacgccct taaacactct catgccgacg atgtggtggt gacagtgacg
     3421 caatgtggca aacaggtcaa actaaaagtg caggacaatg gctgcggcgt cccggaaaac
     3481 gccgaacgca gtaatcacta cggcatgatc atcatgcgcg atcgggcgca aagtttgcgc
     3541 ggcgattgcc aggtacgccg acgcgagact ggcggaacag aggtcactgt tacttttatt
     3601 ccagaaacaa acttcacaga aacccaggga gatacccatg aataatcagg aaccggcaac
     3661 catcctgtta atcgatgacc atccgatgct acgcacgggt gtaaagcagc ttgtgagtat
     3721 ggcgcccgat atcagcgtgg tcggagaagc cagcaacggt gagcagggta ttgacctggc
     3781 ggaatcgctc gatcccgatc tgatcctcct tgatttgaat atgccgggaa tgaatggtct
     3841 cgaaacgctg gataaattac gcgaaaaagc gctgtcagga cgtattgtcg ttttcagcgt
     3901 atccaaccat gaagaagatg tcgtcacggc gctaaagcgc ggcgcggatg gttatctgtt
     3961 gaaagacata gagccggagg acttgctcaa agcgttacaa caggccgccg ccggcgaaat
     4021 ggtattaagt gaagcgttaa cgccggtact ggcggccagc ctgcgggcca accgcgctac
     4081 caccgatcgc gatgtgacgc aactcacccc gcgtgagcgc gatattctga agctcatcgc
     4141 gcagggattg ccaaataaga tgattgcccg gcgtctggat atcaccgaaa gtacggtcaa
     4201 agtgcacgtg aaacatatgc tcaagaaaat gaagctgaaa tcgcgcgtgg aggccgccgt
     4261 ctggatgcat caggaacgca tcttttaatt attgctcctg gaacggttgc caatgcggat
     4321 tatcgtccgg catcgtgata aacggttcag tcagcgcgag cgtgatctca ttggaagaga
     4381 cacgctgacc tttttcatcc tcaaccacca ccgataaacg ccagcgattt gccgcgcctt
     4441 cgcggtgatc ccaggccggc ataatgattg tccagccctc ggtactgcgg gtgtccgttc
     4501 ctgccgtcaa acttaatgcc tgtgtatcgc cctgccagct caaatgacga ataccgtgca
     4561 cgctgcgcac ctgcaatttt aacgcaaccg tctcaccagg cgtaagatcc cagggcggcg
     4621 tcgccagaaa aaccgttaac gttttacgct gccgatactc cattgtcggc agcgagttac
     4681 gttgcggcgt atcatagcgg ctaccgcgta atgactggct ttgcgccact tcactggcgg
     4741 caagctgctt tttgagcggc acgccgaagc ggtagttaag cgtcagcccc aggttattct
     4801 gactgacccc gctctcgccc tgtttgtgct gggcggtcat agtaagcaaa ggtactggcg
     4861 tatagttgag acccagtttt aacgcgacag gattgtgata ccccgttccg gagtcaaaca
     4921 gatccacgct atcgccaaag tactgctcca gactaacgct ggtattgata tgctggtaaa
     4981 acggcagccg cacttgcgcg ttgatatcat atccgcgcgc cattcgctgt tctaaggtcg
     5041 ccgtatgcgt ctgccagtcg gcaaaaggct gataatagtt ggcggataaa cgcaaatatt
     5101 ctccccacgc ctccgcgcca aagccggcgc gctgcagatt ttcatccagc agattatcgt
     5161 aaaaggtatt atagccaaga agccagccat cctgcgccca gcgctgtcct atgccaacgt
     5221 tgcttaccag tccgtcagtc tgttgcgtaa gaccaagctg gctccaggtc agatagcgct
     5281 gtttatcctg taaagggata aaccagcttc cgcgactgcc gttaaaatga ccttcgttat
     5341 cgacgttaat atccacgctg gcgctgcccc aggctgatag ccagctttca agctgctggt
     5401 taacctgctc gctgaccaca tcgcgtacct gtccgaaagc gaattgccgc gcctgttcac
     5461 cggtatccag atcgttattt ttcatgctgg cttcgctaaa cgctttggcc atctcggcaa
     5521 aatgcttttc cccttcgtgg gattccggca tcatgcctaa atccggcaga cggttttgat
     5581 cgaaagggtc ttgcgcctgc gcacggatcg taccgctggc agccagcaag agaagcgaga
     5641 gtgagaatga acgaaaaaca atacggctca acgtgtcggc aacttctaca acaaaagata
     5701 agaggaatgg catcagagta aaccataacg tgtccggaca ggttttgcag ccttttctcg
     5761 tgtttccagg aatatcctta ttttttccgc agagcgtccc gggattttct ccacgcattt
     5821 ggcggtaccc ggttcccgag gtaacataac gccattgccg acaaaatttc tcaaggagaa
     5881 gggttatcca tgcaaaatat cgtcattatc gctaacggcg ccgcctacgg cagcgaatca
     5941 ttatttaata gcctgcgtct ggccattgcg cttcgcgagc aggaaagcca tctcgattta
     6001 cgcctgtttt tgatgtcaga tgccgtaacc gcagggttac gcggtcaaaa accagccgaa
     6061 ggctacaata ttcagcaaat gctggaaatt ctaaccgcgc aaaacgtacc ggtaaaatta
     6121 tgcaaaacct gtgcggacgg acgtggtatc actcccctgc cgctgattga cggtgtggaa
     6181 atcggaacgc tggtcgagct ggcgcaatgg acgctggcgg cggacaaagt gctgacattt
     6241 tgaatctgta cgcgggaaaa gctcccgcgt caggatagac ttccggcaag aaaatcaggc
     6301 taacgcgtga gtaataccgc gtttattttt tcttatgcca tttatcatcc tcgccttttt
     6361 cataatcgtt tttaaccgcc gcccaagcga ctttgtgtgc ggtttcctcg cgactggcgt
     6421 catcacgacg atcggcttta tctttatatt gctcccaggc gctattaaac gcttctttgt
     6481 aaatgtcctg ggcatgggct ggaagaacat tccgcacatt atcgggtaaa tcacttttgg
     6541 ctttatacgg catcagcgcc tccgtcttca gggaaaacat taagtgtggt aaacaatgcg
     6601 ttattacgcc agtcgaggag gatttttgct ttttacggaa attaactttt tgttatttaa
     6661 acactgttaa aacaagatac ttgttttact gaccttgaaa gaaaaaaatc gtctacgccg
     6721 taaaactacg taaaaaacca ctaaaaaaat acaaatttct gctattttta ccttctttac
     6781 tctttccaaa atattaacac ctgcacaagg gagacccaca tgacacatgc ctgtgaggcg
     6841 gtgaaaaccc gccataagga gacttcgctt attttcccgg ttcttgcgct ggtagtgctg
     6901 ttcctttggg gaagtagcca gtcactacca gtggttattg gcatcaatat ccttgcactt
     6961 attggtattt taagcagcgc atttagcgtg gtccgtcatg ccgatgtatt agcgcaccga
     7021 ctcggcgaac cctacggatc gcttatttta agcctgtccg tcgttattct tgaggtgagt
     7081 ttaatttccg cgctgatggc taccggcgat gctgcgccaa cgcttatgcg cgatacgctc
     7141 tactctatta ttatgattgt caccggggga ctggtcggtt tttcgttgtt gttgggcggg
     7201 cgtaaattcg caacgcaata tatgaattta tttgggatta agcagtatct tatcgcgcta
     7261 tttccgctgg cgattattgt gctggttttt cccatggcat tgccgcaagc caatttttct
     7321 actggtcagg cattattggt cgcgttaatt tccgccgcga tgtacggcgt atttttgttg
     7381 attcaaacca aaacgcacca gagcttattt atctatgaac atgaagatga aggcgatgat
     7441 gacaatccac accacggtaa accctccgcg cacagtagcg gctggcatac ggtctggtta
     7501 ctcattcatt taattgcggt cattgccgtt accaaaatga atgccagccc gctggaggcg
     7561 ttgctgacca gcatgaacgc tccggtcgcc tttaccggtt tcctggtcgc gctgttaatt
     7621 ctctcgccgg aaggactggg cgcgctgaag gcggtactga ataatcaggt tcagcgggca
     7681 atgaatctgt tcttcggatc ggtgttggcg acgatttcat taaccgtgcc ggtcgtcacg
     7741 ctcatcgcat gggcgacagg taatgatctg gtgtttggtt taggcgcgcc ggaaatggta
     7801 gtgatggtgg cctcgttagt gctgtgccat atttcgttct ctaccggacg caccaacgtg
     7861 ctaaacggcg cggcgtatct ggctttattt gccgcctatc tgatgacgat ttttgcctga
     7921 ta
//
LOCUS       DAJVKX010000170         7900 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.170, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000170 DAJVKX010000000
VERSION     DAJVKX010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7900
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.170"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            65..748
                     /locus_tag="OPY25_004065"
     CDS             65..748
                     /locus_tag="OPY25_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator"
                     /protein_id="HCS0929534.1"
                     /translation="MSALSTTGHNDGITLHCLQSIAQLIPLSSAVFYRVNAYLKPEAY
                     VLHNISNSTHQQYLEHFQPLDPLLPSRFGQQVITVATMTPGICARHRHYYHEFMLPNH
                     VCDMIEIFIRRGHRIIAGISLMRDIPFSSEERLRAQAVQPLLGLAIHDSLQEDNDLAS
                     ILTAKEREIVGMVCEGASNKLIARQLNISLSTVKTHLRNIFAKTEVINRTELVSRTRM
                     SSVQHSLNM"
     gene            complement(853..1410)
                     /locus_tag="OPY25_004066"
     CDS             complement(853..1410)
                     /locus_tag="OPY25_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3156 family protein"
                     /protein_id="HCS0929535.1"
                     /translation="MSSVPWFKNALMNMVLRDLSGWRCEKLTEHSAVLHLNAFTQVIC
                     HVQQKRLFMASIHSCEFRVKGTINYPLQGKIRAHQPGWLKRYPVIFTGSKSTAGLISY
                     LNRFPNLQQALSELDYCRFTLVLHHKEWYCSIELWAASEVVCKMPPLRRYLRLERHQR
                     VLLLSVINMINQAMNQWLQQDADAR"
     gene            complement(1388..2887)
                     /locus_tag="OPY25_004067"
     CDS             complement(1388..2887)
                     /locus_tag="OPY25_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCS0929536.1"
                     /translation="MFKNRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSG
                     GDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVYDYISCGMGRFFAITGALCAYLI
                     VHIFAGTAETILAGVMALVNFESVSEHVAMQHNTWMVGVGMVVVFGILNAIGVEVFGK
                     VEVFLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPLDVSNLSGLFGYIGMAMFMFVG
                     CELVTPMAPEIKKAHRTIPRAMALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLL
                     DTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRIIYGMALDGALPRFL
                     TWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVV
                     ILRIRRPDLPRAYRAPWFPLPQIISSVGIIIAIINIAPPGMNSRDVLIPFGIMLGLTA
                     AYALFWTLCVQRVNPFLPLPVEEVVERAMGNYEKRNNEEMTPDVLRPLV"
     gene            complement(3096..3469)
                     /locus_tag="OPY25_004068"
                     /pseudo
     CDS             complement(3096..3469)
                     /locus_tag="OPY25_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(3484..4785)
                     /locus_tag="OPY25_004069"
     CDS             complement(3484..4785)
                     /locus_tag="OPY25_004069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCS0929537.1"
                     /translation="MNTKIDALNYYGATKKYPLHFPALQDDIDADVVIIGGGFSGINT
                     ALELAEQGITNVVVLEARHLGYGGTGRNGGQVMAGIGHDIEAVKKYVGAAGMETLFKI
                     SNLGAGIIRERIRKYHIDADFVPGYGYLAYNQRQLKTLQQWEKEFKAATPEDDIELYT
                     GKDVQQVIGSDVYCGVLKHMGGGHVHSLNLLLGSAQAANSLGVKIFEYSPVVEVSYGK
                     TVRVRTAMGSVKAAKLLWACDSFLNNLEPEIYKKTLVTYSYQVSTEPLSSELVERISP
                     LRGAFSDIRPVINYYRLTKENRLLFGSATRFLEYTPHDFAAWNRTLLTEVFPYLKDVK
                     IDFAWGGPMACSANLFPQIGTLREHNNVFYVQGYSGFGVTPSHIVCKILAEGINGGSE
                     RYRLMSSIPHATIYGRDSLRLLLVSAGKLIHQTAGFWKGRN"
     gene            4947..6431
                     /locus_tag="OPY25_004070"
     CDS             4947..6431
                     /locus_tag="OPY25_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent phenylacetaldehyde dehydrogenase"
                     /protein_id="HCS0929538.1"
                     /translation="MSDVTLLAEVTTFLRQRHGQFIAGERQAGNGTNFSVTNPATGKI
                     IADVVSTTPAQAKEAMQSARRAFDVWRKMPTLQRGALLLKLADTLAAHREELAQLESV
                     CSGKTIMLSRGLELDQSVAFLRYFAGWAGKITGETLNVSLPSMGEERYTAFTQRQPIG
                     VVVGIVPWNFSIMIAIWKLAAALVCGCTIVIKPSEYTPLTLLRVAELAKEAGFPDGVI
                     NVVNGAGGEIAQQLIAHPDCAKVSFTGSVATGEKVRRSATSSGKRVTLELGGKNAALF
                     LNDLTAQAMVNGILEAGYLNQGQICAAAERFYLPQEKLDTVMTLLRQRLSEIVPGSPL
                     DEKTVMGPLANQVQLEKVLRLIQRAREEGDTIVYGGETLPGEGYFLQPTAVKVRSKNS
                     TLMHEETFGPVCSFIGYQNEKEALSHINDSPFGLAASVWSENISKALRYAEDIDAGMV
                     WVNMHTFLDPAVPFGGMKGSGIGREFGSAFIDDYTELKSVMVRY"
     gene            complement(6567..6947)
                     /gene="iraD"
                     /locus_tag="OPY25_004071"
     CDS             complement(6567..6947)
                     /gene="iraD"
                     /locus_tag="OPY25_004071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HCS0929539.1"
                     /translation="MMTPTIPVALFDRLLVEGISPHELVRRKLICLFNSCAVPGGETL
                     PPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAYHQTLALS
                     LEAMLQDESEPLRLEIAYSNGRWR"
     gene            complement(6947..7432)
                     /locus_tag="OPY25_004072"
     CDS             complement(6947..7432)
                     /locus_tag="OPY25_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HCS0929540.1"
                     /translation="MDAIFLKLDNIKGESQVEGFEDQIEIMSYSHNVAMQVNNDVSLT
                     ERTSGRAHVGEMSLTKFVDLATPVLNEYCCSGRLIRTAVLTLCRNDDGKMRSLIVYTL
                     TNVLISQLSVSGGAGGKPVETMSLNFTKIKWQITAEKSDGAQQESRASVWDLAMDQIG
                     K"
BASE COUNT         2125 a         2023 c         1828 g         1924 t
ORIGIN      
        1 tatgtttcaa cataccacta ttttactgcg ccccgacgcg ctcatccgga tggaaggaga
       61 taacatgtca gccttatcaa ctactggcca taatgacggg atcactctcc attgcttaca
      121 gagcattgcg caactcattc ctctgtcgtc ggcggttttt tatcgtgtta atgcttattt
      181 aaagccggaa gcctatgttt tacataatat ttctaatagc acacaccaac aatatctgga
      241 gcattttcaa ccattagacc cgctattgcc ttcccgattc ggccaacagg ttattacagt
      301 agcgacgatg acgcccggca tctgtgctcg tcatcgccat tattatcatg aatttatgct
      361 acctaatcat gtgtgcgaca tgattgagat ctttattcgt cggggccatc gtattatcgc
      421 gggcatttca ttaatgcgcg atataccttt ttccagcgaa gagcgtttgc gagcccaggc
      481 agtacaacca ttattgggac tggcaattca tgattctctt caggaagaca acgatctggc
      541 gtcaatattg accgccaaag agcgtgaaat tgtgggaatg gtctgcgaag gggccagcaa
      601 caaattgatt gcccgtcagt tgaatatttc tctctcaaca gtgaaaacgc atttacgtaa
      661 tatttttgct aaaacagaag tgataaatcg cacggaactg gtttcccgaa ccagaatgtc
      721 ctcggtacaa cattcactga atatgtgaaa gcgttctttt taacccgcgt caattgcggg
      781 tcttttcccc atatgtcata tatgcctgaa ttaataccac cctctgagct gatgccgcaa
      841 taaaatgtca tattatctgg cgtcggcatc ctgttgcagc cattgattca tggcctgatt
      901 gatcatattt atcacactaa gcagaagaac acgctggtgc cgctcaagcc gcagataacg
      961 gcgcagcggc ggcattttac aaaccacttc gctagcagcc catagctcaa tgctgcaata
     1021 ccattcctta tgatgtaaaa ccagagtaaa ccgacaataa tccagttcac tcagagcctg
     1081 ttgtaaattg gggaaacgat taagatagct aatcagcccg gcggtacttt tactgccagt
     1141 aaaaatgacg ggataacgtt tcagccatcc gggctgatga gcgcgaattt tgccctgcaa
     1201 aggataattg attgtgcctt tcaccctgaa ttcacaactg tgaatactgg ccatgaataa
     1261 ccgtttttgc tgaacatggc agataacctg ggtaaatgca ttcagatgca gcacggcgct
     1321 atgttcggtc aatttttcac aacgccagcc gctcaaatca cgtaacacca tattcattaa
     1381 tgcgttctta aaccagggga cggaggacat ctggcgtcat ctcttcattg tttcgctttt
     1441 cataattgcc catcgcccgt tccacgacct cttctaccgg aagcgggagg aaaggattaa
     1501 cccgttgcac acataatgtc cagaataagg cataggcggc agtcaatcca agcataatac
     1561 cgaatggtat aagtacatcc cgactgttca ttcctggagg cgcgatatta ataatggcga
     1621 taataatacc cacgctcgaa ataatctgag gtaagggaaa ccagggggcc cggtaagcgc
     1681 gtggtaaatc ggggcgccga atacgtaaga taacgaccga taacgttacc agcagataag
     1741 ctactcccca ggcgcagacc gcagcgagga tcagcggaac aatgtggtcg atatcaccgt
     1801 tcagatacca ggcatgtaaa cagggaatcg caacaccgaa tgcgatggcg atgaccggtg
     1861 ttttaaagcg ggggtgcaac caggtcagaa accgcggcaa agcgccgtcc agcgccatgc
     1921 cgtatataat acgcggtact gccgccatta gcgtattaat cgtcgcacat cccgctaaca
     1981 acaaccccac gcccagccag tattgcccga catgtcccat gacacgattg gcaaaggcgg
     2041 gaatagccat cggcgtatcc agtaaaaaga tatggtttgc cgcatcgacc accacattat
     2101 ttacctgccg gttaatcgca gcgccataga ggaacataca acctgccacc gctaaaaggc
     2161 caagcgccat cgctctggga atcgtacgat gcgctttttt aatttccggc gccattggcg
     2221 tgaccagttc acaaccgacg aacataaaca tcgccatgcc tatataacca aacagaccag
     2281 aaagattact gacatcaagc ggtgcgccaa accacccgga atgatgagtg accggggata
     2341 acaggatccc gcataaaccg aagatggtca gggtagtcca cataccgaat gtaagaaaca
     2401 cttccacctt gccaaatact tcaacaccaa tggcattcag tatcccgaaa accactacca
     2461 tgccgacgcc aaccatccag gtattgtgct gcatggccac gtgttcgcta acggactcaa
     2521 agttcaccag cgccatgacg ccagcgagaa tcgtttctgc cgtgccggca aaaatgtgta
     2581 cgatcaggta agcgcaaagc gcaccggtga tagcgaaaaa acgccccatc ccgcaggaga
     2641 tatagtcgta gacggagcca gtcgtgggaa tgagcgttgc cgcttcggca aaggtggtaa
     2701 tctgcgcttg catcataata aatgccagta ataccgcaag ggcaaaggta tctccccctg
     2761 agccaaaacc actggtcacg gtcaggatca ccgggcttgc cataatcagc ccgacggagc
     2821 tggcaagcgt cgtggggaaa ccaataacgc cacgttcaag atggctggca agtctgtttt
     2881 taaacatggt caacctcttc actattatta caacaataaa ttaccgctcc ggaataacgc
     2941 ttatttatgg caggcagcgc atctaacagg tatcgtcctg aagagggata acggtaaata
     3001 acgttgtgac gccgtccccg catgcgctaa tagcaagtgg ggagcgcgtt attctcccca
     3061 gtgatgccaa cgctactgac gaacaattaa agggttcaac cctgtttatg gctttcaacg
     3121 tttgccagat aatgttttac aaaacggggc gttaaaactt tccatgccac ttcggttccc
     3181 tgttcaacaa accaactatc gcccggtgaa aaacgtatcg gttcctgacc cacaacagtg
     3241 agttccactt ccccttccag cacggttgcg tgctcggtaa agggataaat catagtgaaa
     3301 ccgccgcggg tcgatgaaaa cagtccacag gtaaatacgt cctcaggttt accgtaaatc
     3361 atcgcaacgg cgacctgggg acgccttctg ttggcaacgc ccctaacagg ctgacactcc
     3421 cgactggctg taattcagga acaggttgat tgagtttaaa agcgtgcatt aatgttctcc
     3481 tggttaattc cggcctttcc agaaaccggc tgtttgatgt atcagttttc ccgcactgac
     3541 cagcaataga cgtagactgt cgcgaccata aattgtcgcg tggggaatgc tactcatcag
     3601 acgataccgc tcggaaccgc catttattcc ttcggccagg attttgcata caatatggga
     3661 aggcgtgacg ccaaatccgg aataaccctg aacataaaaa acattattgt gctcacgaag
     3721 cgtgccaatc tgcggaaaca gattcgcgct acaggccatc ggtccgcccc aggcaaaatc
     3781 gattttaacg tctttcaaat aaggaaagac ctccgtcaac agagtgcggt tccaggcagc
     3841 aaaatcgtgc ggggtatatt caagaaacct tgtggcgctg ccaaacagca gacggttttc
     3901 ttttgtgaga cggtagtaat ttatcaccgg gcggatatcg ctaaaagccc cgcgcaaggg
     3961 actgatccgc tcaacaagct cgctggagag aggttctgta gagacctgat aagaataagt
     4021 aaccagcgtt ttcttataaa tttctggttc cagattattg agaaaactat cacaggccca
     4081 cagcaatttg gctgctttta cgctgcccat cgcagtacgt acccgcacag ttttaccgta
     4141 actgacctca accacaggtg aatattcgaa tatcttcacc cccagcgaat tcgcagcctg
     4201 agcggagccc agcaataaat tcagcgagtg gacatgccct ccccccatat gcttgagaac
     4261 accgcagtag acgtcggaac cgataacctg ctgcacgtct ttaccggtat agagttcaat
     4321 atcgtcttcc ggcgtagcgg ctttgaattc tttttcccat tgttgcagcg tttttaactg
     4381 ccgctggttg taggccagat aaccatatcc ggggacaaaa tcagcatcaa tatggtattt
     4441 acgaattcgc tcccgaataa tacccgcgcc gaggttcgag attttaaaca gcgtctccat
     4501 tcccgctgcg cctacatatt ttttaacggc ttcgatgtcg tgacctatac cggccatcac
     4561 ctgaccgccg tttcgcccgg tgccgccata cccaagatgg cgggcttcca gaacgacaac
     4621 attagtgatc ccctgctccg ccagttccag cgcggtattg atgcctgaaa agccaccgcc
     4681 aatgatcacc acatcggcat caatatcgtc ttgcagagca ggaaaatgca acgggtattt
     4741 tttcgtcgcg ccgtagtaat tcaacgcatc gatttttgta ttcatcgcgt taccttgtca
     4801 tcacgcttga ccaagaccgc tatcacagca cggtaacgtt ttacaaaata tcgtccggaa
     4861 gaatgacgtt ctttggaacg atattcagtt ccaggcaagt atgttgagat ggaaaaacgt
     4921 acattcctga cctacaggca cttctgatga gcgacgtgac attacttgcc gaagtaacga
     4981 cttttttacg ccaacgacac ggacaattta ttgcaggtga acgtcaggcc ggaaacggca
     5041 cgaacttctc ggtcactaac ccagccaccg gcaaaatcat cgccgacgtt gtgtcgacaa
     5101 cccctgcgca ggcaaaagag gccatgcaga gcgccagacg ggcgtttgat gtctggcgta
     5161 aaatgccaac gttacaacgc ggcgcattac tgctgaaact ggctgatact cttgccgctc
     5221 atcgtgaaga gttagctcaa ctggaaagcg tctgttcagg taaaacgatt atgctgtcgc
     5281 gcggtcttga actcgatcag tcagtggcct tcctgcgtta ctttgccggt tgggcaggaa
     5341 aaataaccgg tgaaacgctg aatgtctccc tgccatcaat gggagaagag agatacacag
     5401 cgtttaccca acgccaaccc attggcgtgg tcgtcggtat tgtgccgtgg aatttctcaa
     5461 ttatgattgc tatctggaag ctggccgcag cgctggtatg tggctgcacc atcgtcatta
     5521 aaccaagtga atataccccg ctgacactgc tgcgagtcgc tgaactggct aaagaggctg
     5581 gtttccctga tggcgtaatt aacgtggtaa acggtgctgg cggtgagata gcgcaacagc
     5641 tgatcgcgca tccagattgc gccaaagtga gtttcaccgg gtcagtcgcg acaggtgaga
     5701 aagtccggcg ttcggcaacg tcgtcaggaa aacgcgttac cctcgaactg ggagggaaaa
     5761 atgcggcgct gtttctcaat gatctcacgg cacaagccat ggtcaacggt attcttgaag
     5821 ccggttatct gaatcaagga cagatttgtg ctgccgcaga gcgtttttat ctgccccagg
     5881 aaaaactgga tacggtcatg acgctcctca gacaacggtt atcggagatc gtgcccggct
     5941 cgcctttaga tgaaaaaacg gtgatgggcc cgctggcgaa tcaggttcag cttgaaaaag
     6001 tgctgcgtct gattcaacgt gcacgggaag aaggggatac cattgtttac ggcggtgaaa
     6061 ctttacccgg cgaagggtac tttttacagc cgacagcggt aaaagtgcgt agtaaaaaca
     6121 gtacgctgat gcacgaggag acctttggcc ctgtctgtag ctttatcggt tatcagaatg
     6181 aaaaagaggc gctttcgcat atcaacgatt cgccattcgg ccttgctgca agtgtgtggt
     6241 cggaaaatat atctaaggca ttacgctacg ctgaagatat tgatgctggc atggtgtggg
     6301 tcaatatgca taccttcctc gatcccgcgg taccctttgg agggatgaaa ggatcgggca
     6361 ttggtcgtga atttggcagc gcgtttattg atgactatac cgaacttaaa tcggtcatgg
     6421 tccgttatta accatcctga aaatgatgca ggcagatcaa ccataccgaa aggaggactg
     6481 tctgcctgat tatcaggttc gctcgctgcg tttttttgct tttgggataa tgttaaacgc
     6541 ccggcccggc gttccttcct gcattactag cgccatctac cgttagagta ggctatctcc
     6601 agtcttaacg gttcagactc atcctgtaac atcgcttcca aagacaacgc cagcgtctga
     6661 tgataggcat cttttacact gactttcagc atgttgatgc tcggttcata acgtaaaata
     6721 gcagcgcgaa gctcacggca aaaccagttg agaacccgtt tgtcacccac attcacctcg
     6781 tgccattccg gcataccccg agtgagcagc ggcggtaatg tctcgccacc tggcacggcg
     6841 caagagttga ataaacatat taatttgcgg cgtaccaatt catgtgggct tatcccctca
     6901 accaagagcc tgtcgaatag cgcgaccgga atggttggcg tcatcatcat ttccctatct
     6961 ggtccatcgc cagatcccat actgacgctc tggactcctg ttgagcgccg tctgatttct
     7021 cggcagtgat ttgccatttg attttcgtga agttcagcga catcgtttcc accggcttac
     7081 cgccggcgcc gccgctaaca ctgagttgtg atatcagcac gtttgtcagg gtataaacga
     7141 taagcgaccg cattttgccg tcgtcattgc ggcacaacgt cagcaccgcg gttctaatta
     7201 gcctcccgct acagcagtac tcattgagca caggcgtggc gaggtcgaca aatttggtga
     7261 gcgacatttc accaacatgc gcacgcccgg aagtccgctc agtgaggcta acatcgttat
     7321 ttacctgcat tgccacattg tggctataag acatgatctc tatctgatct tcaaagcctt
     7381 caacctggct ttcgcctttg atattgtcga gctttaaaaa aatcgcatcc atgatttatc
     7441 tccttgttga tcaggtggca gttcagcagc cagacgaata ccggcggcca acgcttgtga
     7501 ctcttattaa aagcgcaacg accaaaaaac acagcgtgaa aagcgccagg tttgcaggga
     7561 ttttgccaac gtttacccac gtctgatgaa cgttattccg ctggttgcaa tgcaatagag
     7621 ggttttggcc cgctgtggcc aaatacaatt gaggttatac tgaacgctct ctgccatatt
     7681 caatcccttt tatcgcaaag tatccctggt gccggtatca cagcgtcgtt attcaaaaat
     7741 tgacatttca gaataataat cagctatata taaaaaacac atcaagaagc aaatatcaac
     7801 ttaattttta cttatttaat aaaaaaaatc caaattgatt tacatcaatt aacacataca
     7861 aaagcattaa aaatcaaagc attaaataaa aataatcact
//
LOCUS       DAJVKX010000171         7840 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.171, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000171 DAJVKX010000000
VERSION     DAJVKX010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7840
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.171"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(186..1370)
                     /locus_tag="OPY25_004073"
     CDS             complement(186..1370)
                     /locus_tag="OPY25_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929541.1"
                     /translation="MVHAQSASPRHPIFTALFGMMVLTLGMGVGRFLYTPMLPVMLAE
                     KQLTFNQLSWIASANYAGYLAGSLLFSFGLFHLPSRLRPMLLASAVATGILILSMAIF
                     TQPAVVMLVRFLAGVASAGMMIFGSMIVLHHTRHPFVIAALFSGVGAGIALGNEYVIG
                     GLHYALSAHSLWLGAGALAGILLLIVAMLIPPRAHALPPAPLARIENQPMSWWQLALL
                     YGFAGFGYIIVATYLPLMAKSAGSPLLTAHLWSLVGLAIIPGCFGWLWAAKHWGVLPC
                     LTANLLIQSACVLLSLASDSLLLLILSSIGFGATFMGTTSLVMPLARQLSAPGNINLL
                     GLVTLTYGIGQILGPLAASLSGNGASAIINATLCGAAALFFAALISTAQQIKQKRFVI
                     RE"
     gene            complement(1590..2861)
                     /locus_tag="OPY25_004074"
     CDS             complement(1590..2861)
                     /locus_tag="OPY25_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HCS0929542.1"
                     /translation="MNKIAELKRAKRLALSLLLIAAATFVTTLFLPPSFWVLSVKAIA
                     EAAMVGALADWFAVVALFRRIPIPFISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     IALIRRHEPALLIGNWFSQPDNASRVGQHLLQIMSGFLELTDDARIQRLLKRAVHKAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDSSRTFIARQIIRWLETEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISHDRAHQIRHAFDRATYKLIDKLKHDP
                     EMAARAENIKSYLKEDEAFNRYLGEIWADLRQWLKTDINAEDSKVKQRIAHAGQWFGE
                     TLIADDALRASLNGHLEQAAHRVAPEFAAFLTRHISDTVKGWDARDMSQQIELNIGKD
                     LQFIRVNGTLVGGAIGLVLYLLSQIPALLSI"
     gene            complement(2948..4189)
                     /gene="mdtM"
                     /locus_tag="OPY25_004075"
     CDS             complement(2948..4189)
                     /gene="mdtM"
                     /locus_tag="OPY25_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HCS0929543.1"
                     /translation="MQRIIQFFSQRATTLFFPMALILYDFAAYLTTDLIQPGIINVVR
                     DFNADVSLAPASVSLYLAGGMALQWLLGPLSDRIGRRPVLIAGALIFTLACAATLLTT
                     SMTQFLVARFVQGTSICFIATVGYVTVQEAFGQTKAIKLMAIITSIVLVAPVIGPLSG
                     AALMHFVHWKVLFGIIAVMGLLALCGLLLAMPETVQRGAVPFSAVSVLRDFRNVFRNP
                     IFLTGAATLSLSYIPMMSWVAVSPVILIDAGGMSTSQFAWAQVPVFGAVIVANMIVVR
                     LVKDPTRPRFIWRAVPIQLSGLATLLLGNLLLPHVWLWSVLGTSLYAFGIGMIFPTLF
                     RFTLFSNNLPKGTVSASLNMVILTVMAVSVEVGRWLWFHGGRLPFHLLAAVAGVIVVF
                     TLATLLQRVRQHEAAELAAEK"
     gene            4668..5633
                     /locus_tag="OPY25_004076"
     CDS             4668..5633
                     /locus_tag="OPY25_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012548938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCS0929544.1"
                     /translation="MKKSTTSTPHDAVFKTFLRHPETARDFMEIHLPVSLRQLCDLRT
                     LKLEPGSFIEKNLRAYYSDVLWSLKTREGDGYIYVVIEHQSTPDAHMAFRLMRYAMAA
                     IQQHLDAGHKHLPLVVPMLFYHGVDSPYPFSLCWLDEFANPEVARRLYAAAFPLVDIT
                     VVSDDDIMQHRRIALLELIQKHIRQRDLLGLVERIASLLVTGCANDRQLKALFNYLMI
                     QHGHTPRFTTFIRDVVGHVPHTKERLMTLIERIRAADRRKGERQGRQLGLEEGLAEGL
                     EKGLEKGQHVAALRIARQMLADGLDRETVQRFTGLTAEELQDVSH"
     gene            5814..7185
                     /locus_tag="OPY25_004077"
                     /pseudo
     CDS             5814..7185
                     /locus_tag="OPY25_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463378.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
     gene            complement(7281..7424)
                     /locus_tag="OPY25_004078"
     CDS             complement(7281..7424)
                     /locus_tag="OPY25_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929545.1"
                     /translation="MVVWGGSRKIPYQPPHRTENAGIMNVCTNNTGIKSTVSATWINK
                     EGD"
     gene            7391..7555
                     /locus_tag="OPY25_004079"
     CDS             7391..7555
                     /locus_tag="OPY25_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1127 domain-containing protein"
                     /protein_id="HCS0929546.1"
                     /translation="MEFYENRPRQPFIGYVQLRRALKRWWLRKRACQALRRMSDEQLR
                     DIGLERKDVE"
     gene            complement(7630..>7840)
                     /locus_tag="OPY25_004080"
     CDS             complement(7630..>7840)
                     /locus_tag="OPY25_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929547.1"
                     /translation="FPKGKIHAAIIILLIIAAAIIIPGIFNKKEKMTITIDKEKYHAI
                     EQKTKIKPEKYIEKKINDININDIK"
BASE COUNT         2003 a         1981 c         2149 g         1707 t
ORIGIN      
        1 gaagggtata taaaataata gacagattga taacactaaa aaccatagaa taagtatagt
       61 ttttagtggc atctttacct tgaaataacg tgttgaggat gtgctattaa aaacagatcc
      121 gcattgcgcc gcgaatagca ttaaagatac aacccggtgc ggatagcgcg ggtttactct
      181 accgcttatt cacgtatcac aaaccgtttt tgttttatct gctgcgcggt gctgatcagc
      241 gcggcaaaaa agagcgccgc ggcgccgcaa agcgtggcgt tgataattgc cgacgcgcca
      301 ttgcctgaca gactggcggc gagcggaccg agaatttgcc caataccata cgttagcgtc
      361 accaggccta acaaattaat attgcccggc gcgctgagct ggcgggcaag cggcatcacc
      421 agtgaggttg tgcccataaa cgtggcgcca aaaccaatac tgctcagtat taacagcaac
      481 aacgagtcgc tggcgagaga cagcagcacg caggcgctct ggatcaacag gttcgcggtc
      541 agacatggca ggacgcccca atgttttgcc gcccacagcc agccgaagca gccgggaatg
      601 atcgccaggc cgaccaacga ccaaaggtgt gccgtgagta gcggagagcc cgcgcttttc
      661 gccatcagcg gcaaataggt agcgacaatg atgtagccga atccggcgaa accgtataac
      721 agcgccagtt gccaccagga cataggctga ttttcgattc ttgctaaggg cgcaggcggc
      781 agcgcatgag cgcggggggg aatcaacatt gccacgatta atagcaatat accggcgagc
      841 gctccggccc ccagccatag cgaatgggcc gaaagcgcat aatgtaaacc gccaatgaca
      901 tattcgttgc ccagtgcaat cccggccccg acgccggaaa agagcgcggc gatcacaaac
      961 ggatggcggg tatgatgcaa cacaatcatt gatccaaaaa tcatcattcc cgcactcgcg
     1021 acgcctgcca ggaagcgcac caacatgacg accgcgggct gagtaaatat cgccatagac
     1081 agaataagaa taccggtggc gaccgccgaa gccagcagca tggggcgtag acgagagggg
     1141 agatgaaaaa ggccaaagga aaacagtaag cttcccgcca ggtaccctgc ataattggcg
     1201 ctggcaatcc aagagagttg gttaaacgtt agctgctttt ccgccagcat taccggcagc
     1261 atgggcgtat acagaaagcg gccaactccc atccccagcg tcaataccat cataccgaaa
     1321 agcgccgtaa aaatgggatg gcgaggtgaa gcgctctgag catgaaccat ggtttttctc
     1381 tttgctaaag taaggcagga atgccggatt gtcgttgtaa atgataataa aaagtaaaat
     1441 taatgtttca aatttgcaag aaaagaaagt gaagcgcagg cgaataacgg attgagaaga
     1501 ggggcatcgg tgggaaatgg cattaaatta atgcctccca cgtgcggggt ttggcagtta
     1561 atctgaatga gaattgcgcc ttccccttct tagatactga gcagtgccgg tatttgcgac
     1621 agtaaatata acaccagacc aatagcgccg ccgaccagcg tgccgttcac gcggataaac
     1681 tgcaaatctt taccgatatt aagctcaatc tgctgcgaca tatcgcgcgc atcccagcct
     1741 tttacggtat cgctgatgtg gcgcgtcagg aaggcggcga attccggcgc gacgcggtgc
     1801 gcggcctgtt ccagatgacc gttaagcgag gcgcgtaatg cgtcgtcggc gatcagcgtc
     1861 tcgccaaacc attgtccggc atgagcgatg cgctgcttca cctttgagtc ttcggcgttg
     1921 atatctgttt ttaaccactg gcgcagatcc gcccagatct cgccgagata gcggttaaac
     1981 gcctcatctt ccttcagata acttttaata ttttctgccc gggcagccat ttccggatca
     2041 tgtttaagct tatcgatcag cttatacgtc gcacgatcga aggcatgacg aatctgatgt
     2101 gcgcggtcgt gactgatatc atccagcaga gaattcaccg cgtcggagac cagttcagcg
     2161 ctgtgttctc ccagccattc ggtcggcaga atcttcgctt ttaacggatg ctcggtttcc
     2221 agccagcgta tgatctgtct ggcgataaat gttcgggagc tgtcacgttg taacagggcg
     2281 ataagctggg cgatcagcgt atcgagtaac acctggtgac gatcgttttt ggtcatgctt
     2341 tccagcatca gggcgctggt gccggaaaga tccactttat caatcgcctt atgtaccgct
     2401 cgcttgagca gccgctgaat acgggcgtca tcggttagtt ccagaaagcc gctcataatt
     2461 tgcagcagat gctgcccgac ccggctggcg ttgtccggct ggctgaacca gtttccaata
     2521 agcagcgcgg gttcatggcg gcggattagc gcgatcagcg actgcgtatc aaggaacttc
     2581 tcctgtacaa attgcccaag attttcgccg attcggtctt tgttacgggg aataatcgcc
     2641 gtatgtcgtg aaataaacgg aatgggaatg cggcgaaaca gcgccaccac ggcaaaccag
     2701 tccgccagcg cgccaaccat cgccgcttcg gcaatagctt ttacgctcag cacccaaaaa
     2761 ctgggcggca ggaaaagcgt ggtcacaaac gtcgcggcgg ctatcagcaa cagtgagagc
     2821 gccaggcgtt tggcgcgttt gagttcggcg attttattca tagggttaag gatagagcca
     2881 gacggcagga acgtgcaaaa aatatcagat gatcctgtgc cggataagcc tctatccggc
     2941 agagtgttta cttctcagcg gccagttctg ccgcctcatg ctggcgcacg cgctgtaata
     3001 atgtcgccag ggtgaagacc acaatcaccc cggccaccgc tgccagcagg tgaaacggca
     3061 gtctcccgcc gtgaaaccac agccagcggc caacttcgac cgacaccgcc atcaccgtca
     3121 gaatcaccat gttcagcgag gccgaaaccg tcccttttgg caagttgttg gagaaaagcg
     3181 tgaagcgaaa cagcgtcggg aaaatcattc caatgccgaa cgcgtacagg ctggtgccca
     3241 gcacagacca aagccagacg tgcggcagaa gaagattacc gagaagcaat gtcgccagcc
     3301 cgcttaactg gattggtacg gcgcgccaga taaaacgcgg tcgggttgga tctttcacca
     3361 ggcgcacaac gatcatattg gccacgatca ccgcgccgaa tactggcacc tgcgcccagg
     3421 cgaattgcga agtactcatc ccgccggcat cgatcaggat caccggcgac accgccaccc
     3481 agctcatcat cgggatgtag ctcaacgaca gcgtcgccgc cccggtgaga aaaatcgggt
     3541 tgcgaaacac attacgaaaa tcgcgcagta cgctcaccgc gctgaacggc accgcgccgc
     3601 gttgcaccgt ttctggcatc gccagcagca ggccgcacaa cgccaacagt cccatcaccg
     3661 caataatacc gaacagtacc ttccagtgaa cgaagtgcat cagcgcggcg ccggagagcg
     3721 ggccgataac cggagcgacc agcacaatgg aggtaataat cgccatcagc ttaatggctt
     3781 tggtttgacc gaaagcctcc tgtaccgtga cgtagccgac cgttgcgata aagcaaatgc
     3841 tggtgccctg cacaaaacgg gcaaccagaa actgcgtcat tgaggtcgtc aacagcgtag
     3901 ccgcgcaggc gagagtaaaa attaatgcgc ctgcaatcag cactggccgg cggccaatcc
     3961 tgtcggatag cggccccaga agccattgca acgccattcc tcccgccaga tagagactga
     4021 ccgaggccgg cgcaagactg acgtcagcat taaaatcgcg cacgacgtta atgatgccag
     4081 gctgaatcag atccgtcgtc agataggcgg caaaatcgta caaaatcagc gccatcggga
     4141 aaaataacgt tgtggcgcgt tgggagaaaa actgaataat ccgttgcata aaaaatgcgc
     4201 tccatgtcgg agaaccccat gatgggacag cgaaactcaa taccgtcatc gtgacgtcag
     4261 gcaggcgatg gaaacagcgg ctgcggatgt actgaatttc atgtaatcaa aaacgctgcc
     4321 ggtgaaaaca cagacaggaa gagacgcgtt ctgaatctcg tcagaacgtg tggcgattac
     4381 agataacaat cagcacatca cacctcggga aatttacgtt gcacggaaaa tatacacatt
     4441 aagtgtaatt aaattttgat gttaatcaaa agagtttgtc tggttaataa agataaaggc
     4501 agggcgcgca ggctggtatt ttgcgtgttc agttccgaaa atgcatgtgc attacagata
     4561 acaggattta tctttcgtcg cgcctcgcaa tgctgaaaag gtacggatga gaaaggaatt
     4621 ttcaggaggt agagtcgcag catcctggtt ttgggtgacg gagcgccatg aaaaaatcga
     4681 cgacctcaac accgcatgat gcggtgttta aaaccttttt gcgccacccg gaaaccgccc
     4741 gcgattttat ggagattcat ctgccggtgt cgttacgcca gctttgcgat ctgcggacgc
     4801 taaagctgga gcccggcagc tttattgaaa aaaatctgcg agcctattat tccgatgtgc
     4861 tttggtcgct gaaaacgcgc gagggcgacg gttatatcta tgtcgtgatt gaacatcaga
     4921 gcacgccgga tgcgcatatg gcgtttcggc tgatgcggta tgcgatggcg gcaatacaac
     4981 agcatctgga tgcggggcat aagcatcttc cgctggtggt gccgatgctg ttttatcacg
     5041 gtgttgatag cccgtatcct ttttcgctgt gctggctgga tgagtttgcg aacccggaag
     5101 tggcaagaag actctatgcc gctgcctttc cgctggtcga cattacggtg gtatcggatg
     5161 atgacattat gcagcaccgc cgcattgcgc tgctggagct catccaaaaa catatccgcc
     5221 agcgcgacct gctgggactg gttgaacgga ttgcttcgct gttagttact ggttgcgcta
     5281 atgacaggca gcttaaagcg ctgtttaatt atcttatgat tcagcacgga catacgcctc
     5341 gtttcaccac gtttattcgt gatgtggtag ggcatgtccc gcacactaag gagagactga
     5401 tgacgctgat agagaggatc cgcgcagcgg atcgcagaaa aggggaacgg caaggaagac
     5461 agctcggtct ggaggaagga ttagcagaag gattagaaaa agggctggaa aaaggtcagc
     5521 atgttgccgc attgcgtatc gccagacaga tgctggcgga cggacttgac cgcgagactg
     5581 tccagcggtt caccggcctt acggctgaag agcttcagga tgttagtcac taacgcggct
     5641 ccagtctgaa tgttgcaggc ccggtgccca ccgggcaacg cgctctataa ttatcgttga
     5701 taaccgtacg aatataccga actttaccga tagcgccagc catctctact acccttattg
     5761 ttctgagcgg catttccggc tgccttaatg acgataacaa ggagacatgt gatatggctt
     5821 accagacagt gaatcctgcc aataatcagc tcattaaaga gtatcccccg cacacggacg
     5881 cggatattga agccgcgctg caaaaagctg acgcgctcta tcactccgac tggtccaggg
     5941 gagagattga ccaacgtttg ccggtactgc ataagctggc tgacttgatc gacagccgtg
     6001 ttgaagaact ggcaaaaatc gccagccagg agatgggcaa gctcatcgag caaagccgtg
     6061 gcgaagtcaa actctgtgcg cagatcgctc gctattatgc ggataacgcg aagcagtttc
     6121 ttgtcccggt gccttataaa accgagtttg gcgacgcgtg ggtagaacat catccgattg
     6181 gcgtcatcat ggctgttgag ccgtggaact tcccgtacta tcagttgatg cgtgtgctgg
     6241 cgccgaacct ggccgctggt aacccggtgc tggcgaaaca tgccagcatc gtaccgcact
     6301 gcgccgagac atttgcccat ctggtgcgtg aagccggcgc gccggatggc gcatggacca
     6361 acctgtttat ttcctccgat caggtggcga atatcatcgc cgacccgcgc gtgcagggcg
     6421 cggcgctgac cggatctgaa aaagcgggga gcgccgtggc ggcacaggcg gcgaagcaca
     6481 ttaaaaaatc gacgctggaa ctgggcggga acgatgtgtt cgtcgtgctg gacaatgccg
     6541 atcttgagaa agcggtgaaa attggcgtgc aggcacggct cactaatgcg gggcaggtat
     6601 gtacggcggc gaagcgcttt atcctgcatg agaaaatcgc cgatcaattc ctcagccagt
     6661 tcaccgaggc gttcaggaag gtgaaggtgg gggatcagat ggacgcttct accgaactgg
     6721 ggccgctgtc gtcgaaagat gcgctggaaa cattgaccag acaggtcgag gaagcggtga
     6781 aaaatggcgc gacgctgcac gttggcggca agccgctgga aagcaaaggc aacttctttg
     6841 agccgaccat tctgacccac attacgcgtg acaacccggc gtactttgaa gagttcttcg
     6901 gcccggtggc gcagatgtat gtggtgaaag acgatgatga ggcggtaaaa ctcgccaacg
     6961 attcccacta cggccttggc ggcgcggtgt ttagtcagga tattgagcgc gctaaacgca
     7021 tgtgcctccc ggattgaaac cgggatggtt tatatcaact ggctgaccga caccgcagcg
     7081 gagctgccgt tcggcggcgt taagcgttcg ggcttcggac gcgagctatc ggatctgggg
     7141 attaaggagt ttgtgaacca gaagctggta gtggtacgcc gctaatccct gttgcccctc
     7201 tgaaaacggg aggggcctgg cttttttgca gcgaaggacg cagatcttaa atcagaacga
     7261 aataaacgaa caaaacaccc tcaatcgccc tccttattta tccacgttgc actaaccgtg
     7321 ctttttatcc cggtattgtt tgtacagaca ttcatgatgc ccgcattttc tgttctatgc
     7381 ggaggctggt atggaatttt acgagaaccg ccccagacaa ccattcattg gctatgtgca
     7441 gctcagacgg gcgctaaaaa ggtggtggct gcgtaagcgg gcctgtcagg cgctgcgacg
     7501 aatgagtgac gagcagttaa gggatattgg gttggaaagg aaggatgtgg aatagtgaat
     7561 ctattcaagg gcaatagtaa gtaaaggatt ttatgatata ttactatgcc cttatgttat
     7621 gcgtgctcac tattttatat catttatatt aatatcatta atctttttct caatgtattt
     7681 ttctggtttt attttggttt tttgctcaat tgcatgatat ttttccttat caatggttat
     7741 agtcattttt tcttttttgt taaatatgcc agggataata atcgcggctg caattatcaa
     7801 taatattatt attgctgcat gaattttgcc tttgggaaat
//
LOCUS       DAJVKX010000172         7756 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.172, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000172 DAJVKX010000000
VERSION     DAJVKX010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7756
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.172"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..295)
                     /locus_tag="OPY25_004081"
     CDS             complement(<1..295)
                     /locus_tag="OPY25_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4765 family protein"
                     /protein_id="HCS0929548.1"
                     /translation="MRITVSDISTRESQQTVQIQAIRSWDTIPYLSMLDGLYQDDIFH
                     EQISNLPEEYIKLDEMAKDEEKNSLNIYEFFFEPTHEIICEEIQSTLDFYYSNS"
     gene            725..877
                     /locus_tag="OPY25_004082"
                     /pseudo
     CDS             725..877
                     /locus_tag="OPY25_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309956.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            983..1918
                     /gene="ttcA"
                     /locus_tag="OPY25_004083"
     CDS             983..1918
                     /gene="ttcA"
                     /locus_tag="OPY25_004083"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HCS0929549.1"
                     /translation="MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEQLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIVRFAEAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVIDGGD
                     LAFDREEIPLQPAGWQPEEDDTALEALRLDVIEVK"
     gene            complement(1962..3336)
                     /gene="dbpA"
                     /locus_tag="OPY25_004084"
                     /pseudo
     CDS             complement(1962..3336)
                     /gene="dbpA"
                     /locus_tag="OPY25_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
     gene            complement(3823..4806)
                     /gene="zntB"
                     /locus_tag="OPY25_004085"
     CDS             complement(3823..4806)
                     /gene="zntB"
                     /locus_tag="OPY25_004085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HCS0929550.1"
                     /translation="MEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLH
                     LNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPD
                     QLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASE
                     FIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMV
                     FLPSTFFTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL"
     gene            complement(4952..6106)
                     /locus_tag="OPY25_004086"
     CDS             complement(4952..6106)
                     /locus_tag="OPY25_004086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemoreceptor protein"
                     /protein_id="HCS0929551.1"
                     /translation="MLRNISVRTCIILFMVCTFLLVDTLQITFLHDLPILITCNIIYL
                     ISALLLWWYMTCYLVVPINTAKKSIEEVAAGNLSIHISEFGNNCAGRLIPGINSLSEN
                     ISALVREIRSSSQTAMTLSEQLAARSLSLSVKTEQQSASLIQTAASMDEMAASTKNNA
                     DNTRMASIQADCATQCARKGGELMVRVTENMRSITDCASQMTEIISLIDGIAFQTNIL
                     ALNAAVEAARAGDHGKGFSVVAREVRNLAHRSAEAAKNIKALIDVTHDNVRQGAAIVQ
                     EAEKNMQEIVGGSGQLNVLMSEISTTTREQEKGINQITLALSDLESATHSNVLMVEAL
                     SASSDVLKAQVIELQTKTDKFRLSQPGYSEHALSRSHVSPLSTITRRGQA"
     gene            complement(6517..7080)
                     /gene="smrA"
                     /locus_tag="OPY25_004087"
     CDS             complement(6517..7080)
                     /gene="smrA"
                     /locus_tag="OPY25_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HCS0929552.1"
                     /translation="MNLDDKALFLDVMEDVQPLKRHTDVHWQPTRNLKTPQRIDTLQL
                     DNFLTTGFLDILPLNEPLEFRREGLQQGVIDKLRSGKYPQQASLNLLRQPVETCRKML
                     FRFILEAQKEGLRNVLIIHGKGREAKSHANIVRSYVARWLTEFEDVQAYCSALPHHGG
                     GGACYVALRKTVQAKQDNWERHAKRSR"
     gene            7338..>7756
                     /gene="ogt"
                     /locus_tag="OPY25_004088"
     CDS             7338..>7756
                     /gene="ogt"
                     /locus_tag="OPY25_004088"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCS0929553.1"
                     /translation="MLRLLEEKIATPLGPLWVVCDEQFRLRAIEWEQYRDRMEQLLNI
                     HYRHEGYERVSATNPGGLSDKLADYFAGNLAVIDTLETATGGTPFQREVWQALRAIPC
                     GQVMHYGQLAAQLGRPGAARAVGAANGANPISIVVPC"
BASE COUNT         1975 a         2028 c         1822 g         1931 t
ORIGIN      
        1 cgctatttga ataataaaaa tccaatgttg attggatttc ttcacatata atttcatgtg
       61 ttggctcaaa gaagaattca taaatattta agctgttctt ttcttcatct ttggccatct
      121 catccagctt aatatattct tctggtaaat tagatatttg ctcatgaaag atatcgtcct
      181 gataaagtcc atccaacatt gaaaggtacg gtatggtatc ccaacttctg atagcttgta
      241 tctgtaccgt ctgctgtgat tctctggttg atatatcact tactgttata cgcattacat
      301 tctccagcca gaattatggt atacatcata aggtgtagat atcaggtagc aattctcatc
      361 gcaaataatt tgtctgaact gtacatatga tacaggctat ttttaattca atatgaccac
      421 cagaataggc aagaaaattt taaatagtat acggtaaaat gatcttaccc aacgataatt
      481 aaacacactg cactatctta ttagataata aaatactgat acgttatttt atatcaccaa
      541 taaaagagca aaaagggtgt gccgaatatc attttacacc tgtcccggtt caccccacgg
      601 aaccacttga aacgtaccat catcaggacg ctgcagcgcc tgaatttcag ttgagcccgt
      661 cacttcttaa cgggcctagc tacatgatgt atacagttga caatatccga aggtactatc
      721 tctattaaaa cgtgctggca ttcgtcgccg taatccgtac catacgcgac atacttttgc
      781 ctgctggctg ttgacggcag gagcgaaccc ggcatttatc gccagccaaa tggggcatga
      841 aactgcgcat atggtgtatg aaatttacgg tatgtagatt gatgacatga acgacgaaca
      901 agtagcgatg ttgaatgcgc ggttatcgta gttgcaaagt ttgcccccaa tttgccccat
      961 ttagtaccag agaactgaaa taatgcaaga aattcaaaag aatacaaaga aagaacaata
     1021 caacctcaac aagttgcaaa agcgcctgcg ccgtaacgtt ggcgaagcga ttgccgattt
     1081 taatatgatt gaagaaggcg atcgcattat ggtttgcctt tctggcggca aagatagcta
     1141 tacgatgctg gaaattttac gtaatttgca gcaaagcgcc ccgatcaatt tttcactggt
     1201 cgccgtcaac ctcgatcaaa agcagccagg ttttccggag catatcctgc cagcctacct
     1261 tgagcagctg ggcgtagaat ataaaatcgt cgaagaaaac acctacggca ttgtgaaaga
     1321 gaagattccg gaaggaaaaa ccacctgctc gctgtgctcg cgtttgcgtc ggggtatcct
     1381 gtatcgtact gcgactgaac tgggcgcgac caaaatcgcc ctgggccacc atcgcgacga
     1441 tattctgcaa accctgtttc tgaatatgtt ctatggcgga aaaatgaaag ggatgccgcc
     1501 gaagctgatg agcgatgacg gcaaacatat cgtgatccgc ccgctggctt actgccgcga
     1561 gaaagatatt gtccgttttg ctgaggccaa agcctttcct atcattcctt gtaatctgtg
     1621 cggttcgcaa cccaacctgc aacgccaggt gattgccgac atgctacgcg actgggataa
     1681 gcgctatcct ggacggatcg agacgatgtt tagcgccatg cagaatgtcg tgccgtctca
     1741 cctttgtgac acaaacctgt tcgatttcaa agggataact cacggttccg aggtcatcga
     1801 cggcggtgat ttagcgttcg atcgtgaaga gattccattg cagcccgctg gctggcagcc
     1861 ggaagaagat gacaccgcct tagaggcgtt gcggcttgat gttatcgaag tgaaataatc
     1921 tgcaggcgtc tcagcactcc gctgagacgc catactatcg atcattttaa tagccgtacc
     1981 cggcatgact tgcctttgat cttcccgttt tgcaactgct tccaggcttt ttgcgctact
     2041 gcttgacgta cggcgacgta aacgtgcatg ggatgcacgt taattttgcc aatatccgcc
     2101 ccgtccaatc caatatcgcc ggtcagcgcg cctaaaatat ctcccggacg cattttcgct
     2161 tttttgccgc cgtcaatgca tagggtagcc atctctgcgg ccagagggag taacggctgc
     2221 cgggcgggcg cattcagcca gttcagcttg agttgcagca tttctgaaag aatattcgcc
     2281 cgctgcgcct cttccggcgc acagaaactg atcgccaggc cgctgcttcc cgcgcgcgcc
     2341 gtacggccaa tacgatggac atgcacctcc gggtcccagg ccagctcata gttaaccacc
     2401 agttcgagcg atttaatgtc taaccctcgc gcggcaacgt cggtggcaac cagaatgcgc
     2461 gcgctgccat ttgcaaaacg caccaacgtc tggtcgcggt cgcgttgttc cagatcgccg
     2521 tggagcgcca acgcgctttg tcctaccgca ttaagcgcat cacaaacggc ctgacaatct
     2581 tttttggtat tgcaaaacac cacgcaggac gctggctgat gctggctaag caacgtttgt
     2641 agcagcgaaa ttttttcatg cgccgacgtt tcgaagaact gctgttcgat agccggtagc
     2701 gcatctaccg tatcgatttc aatacgtatt ggctgctgct gtacacgacc gctaatcgcc
     2761 gcaatggcct caggccaggt tgctgaaaac aacaacgtct ggcgcgtcgc aggcgcaaag
     2821 cggatcacct catcaatggc gtcactgaat cccatgtcca gcattcggtc tgcttcatcc
     2881 attaccagaa tgtgcagcgc atccagcgat acggtttctt tttgtaaatg atccagcagg
     2941 cgccccggcg tcgcgacaat gatatgcgga gcgtgctgaa gcgagtcgcg ctgtgcgcca
     3001 aagggctgcc cgccacacaa ggtcagaatt ttggtatttg gcagaaaacg ggccaggcga
     3061 cgtaactccc cggctacctg atccgccagc tcccgcgtcg ggcacagcac taatgcctgt
     3121 gtctggaaca gagtgacatc aattcgatgc aagagcccaa gaccaaacgc cgccgtttta
     3181 ccgctaccgg tcctggcctt gcacacgcac atcattaccc gccagaatga cgggtaatgc
     3241 tgcggcctgg acaggcgtca tctcaagata gcccagctca gtaaggttat tgagctgggc
     3301 ggcgggcaaa acattcaggg ttgaaaaagc ggtcacaatt tactctcgcg gtaacgactc
     3361 atagtcagca ggcgcgtatc ctcgcagatc cggacgtttg atgcgacatt ttaatcggtt
     3421 cttcgtccgg cggcgggtcg ggcatcggct gaggacgggg aagcggctca ggaatgggaa
     3481 cagggtcagt gggaatcggg tccgacaagg acgagtgtag atataataag gtcaaaagac
     3541 agctcatatt accctccaga atgtcattca gactcttaaa gggtagacgc tgatatccta
     3601 caggcaaaaa aaagccgact aatctaagcc ggcgtcgtac gaatcaattg tgctatgcag
     3661 taattcaaaa aaggaagcaa gacaatatag aacgcaacgc ccatcgcttg acgttgcatt
     3721 cacctgcgag agagatattg ccccgaatag gtagatggtt tattgacttc gctcaaattt
     3781 ctcggcgttt tttcacccaa aacggtctga aaagcgcttt tgttacaacc atttactgcg
     3841 atgcaaccat aaagtaacac caccgatcag gacaactaac agaatacaaa acagagaaaa
     3901 gccgaaccgc catccgccgc caggaatacc gcccaggtta acgccaaata accccgtgaa
     3961 gaaggtgctg ggcagaaaaa ccatcgccat aagcgacatg gtataagttc tgcgcgccag
     4021 agactcctgc atcacctggg caatttcatc cgccatgatg ccagtacgcg cgatacaagc
     4081 gtcaatttca tccagccccc ttcccagcct gtcggcgata tcctgcattc tgcgccggtg
     4141 atcgtcgctc atccacggca gccgttcact cgcaagccgg gcatagacgt cgcgctgcgg
     4201 cgccatatag cggcgcataa caattagctg tttacgtagc aacgcgagga aaccgcgcgg
     4261 tgggatttgc tggtcgagaa gattatcttc cagatcgata attttatcgt gtagctcttc
     4321 aataaattca ctggcgtgat cggttaacgc atcgcataca tccactaacc agccgccgca
     4381 atctacgggc ccggtgccct cctgcaaatc actgaccaca tcgtccagcg ccagaacctt
     4441 tcgctgacgg gtagacacaa tgaaccgctc gtccatatat aaacgcattg ctactaattg
     4501 atccgggcgt tcgtcagtac tgccattaat acagcgcagc gtaatgagcg tcccttcccc
     4561 catacgactt acgcgcgggc gcgagctttc accagccagc gcatcacgca cgttattggg
     4621 gagtaaaggc gttgaagcca accagcgggc gctgtccggg tgggtataat taagatgtag
     4681 ccaacaggga tgctgactat cgatcacatc attatcttcg agcggtttta ctccaccacg
     4741 accatccagt agccatgcga aaacggcatc cggcacgttc acatccgatc ccttaatggc
     4801 ttccacagcg cctccacgtt acaactctca tgccgttagt ctagctttcg ggaaaggtta
     4861 agcaatctct cattttctca ttgcgcaaaa agaatgacgg gaacgtgcga aaaaagcgcc
     4921 ttagcaacag gcgcttacca aacatgtatt atcaggcctg gccgcgcctg gtgatggtcg
     4981 aaagaggtga tacatgagag cgcgacagcg catgttcact gtaacccggc tggcttaaac
     5041 gaaatttgtc ggttttagtc tgtaactcga tcacctgcgc ctttaaaaca tccgaagaag
     5101 cagatagcgc ttcaaccatt aagacattgc tatgggttgc gctttccaga tcgctcaacg
     5161 ccagggttat ctggttaatg cctttttcct gctcccgcgt ggtggtggaa atttcactca
     5221 tcagcacgtt taattgcccg gagccgccaa caatctcctg catatttttt tcagcctcct
     5281 gcactatggc ggccccctgc cgcacattgt catgcgtaac gtcgatcagc gccttgatat
     5341 tttttgccgc ctcagcgcta cgatgcgcca gattacgcac ttccctggcc accacggaga
     5401 aaccttttcc atgatcgccc gcccgcgcag cctctaccgc cgcgttaagc gccagaatat
     5461 tagtctggaa tgcgataccg tcaatcaatg aaataatctc cgtcatctgc gaggcacagt
     5521 cggtaataga acgcatattt tctgtaaccc gcaccattaa ctcaccgcct ttacgggcgc
     5581 attgggttgc acaatccgcc tgtatgctcg ccattcgggt attatccgca ttgtttttgg
     5641 tactcgccgc catttcatcc atactggcgg cagtttgaat taacgaggcc gactgctgtt
     5701 ccgtctttac ggatagcgac agactgcgcg ccgccagttg ttcggaaagg gtcattgccg
     5761 tttgcgaaga ggatctgatt tcacgtacca gcgcggaaat attctccgac aggctattaa
     5821 tcccggggat gagtcgcccg gcgcaattat tgccaaattc ggagatatga atagacaagt
     5881 ttcctgctgc gacctcttca atacttttct tcgcggtatt aattggcact accagatagc
     5941 aggtcatata ccaccaaagc agtaatgccg agatcagata aatgatatta cacgtaatta
     6001 aaatagggag atcgtgcaga aaggttattt gtaaagtatc cactaaaaga aacgtacata
     6061 ccatgaatag aataatgcat gtcctgacgc tgatatttct caacattttt gacggcctac
     6121 aaccaggata ggagacaggt tttattttta tagcatttca gatacctatt gccattcgtt
     6181 tctttgacat tctccatatt caataccaga ccatcgccat ttcccttagt gcaatagata
     6241 aaatcatcta tattcgctat gccaggatat tcatccatcc atattgacaa gtgatgtact
     6301 tatcaccatt ttctgcttaa tagttaagtc gaaagccagt atattttaat agacgcttaa
     6361 ataagtgaat gactgtttct ccgtgttatt actgtggaca gcgttatcgc ccgttctctt
     6421 gcagaatcct gagcgtttgg atgaggcgtt atatcaggca taaaatcggg ttcatgcgag
     6481 cttgcgctgg cggtcctgtc cgccagcggc aacgatttac cgactacgct tcgcatggcg
     6541 ctcccagtta tcctgtttag cctgcaccgt tttacgtaaa gcgacataac atgccccgcc
     6601 gccgccatgg tgcggcagcg ccgaacaata agcctgtaca tcctcaaact ctgtcaacca
     6661 gcgggccaca tagcttcgga cgatattggc atgcgacttc gcctctcgcc ctttaccatg
     6721 aatgatcagg acattacgca acccctcttt ctgcgcctcc aggataaaac gaaacagcat
     6781 ttttcggcac gtttcgaccg gttggcgtaa caaattgagg ctggcctgct gagggtattt
     6841 cccactgcgt aacttgtcga tgacaccctg ctgcaatcct tcccgacgaa attccagcgg
     6901 ttcattcagc ggcagaatat ccagaaagcc cgtcgtcagg aaattatcaa gctgaagcgt
     6961 gtcgatacgc tggggcgttt taagattacg cgttggctgc cagtgtacat cagtatggcg
     7021 tttcagcggc tggacatcct ccatgacgtc aagaaacagc gctttatcgt caaggttcat
     7081 ggttcatcct ccagcgtttt tgcgactgcc gttatcataa ccgtgccctg ttataccgac
     7141 aacggtttac agttatttcc aataacagcg acaatgtcag gcaattaacc gtctcgccag
     7201 gctccctttt tctccgccaa cgatattact gtcgctaaat gtgttatccc tgactatctt
     7261 ttaaggagta tggttgcggg tattcctggc atgatatctt gtctcttacg ttagattaag
     7321 acgatgtgag agaacggatg ctgagattac ttgaagagaa gatagccacg ccattaggtc
     7381 cgttatgggt ggtttgcgat gagcagtttc gactgcgggc cattgagtgg gaacagtacc
     7441 gcgatcgtat ggagcaactg ctaaatatcc actaccgtca cgaaggctat gaacgcgttt
     7501 ctgcgactaa ccccggtgga ctcagcgata agcttgcaga ttattttgca ggcaatctcg
     7561 ccgtaattga taccttggaa accgccacgg ggggcacacc ttttcaacgg gaagtatggc
     7621 aggcgttgcg cgctatcccc tgcgggcaag tgatgcacta tggccaactg gcggcgcaac
     7681 tgggacgacc gggcgccgca cgcgcagtgg gtgctgcgaa tggcgctaac cccatcagta
     7741 ttgttgttcc ctgcca
//
LOCUS       DAJVKX010000173         7701 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.173, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000173 DAJVKX010000000
VERSION     DAJVKX010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7701
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.173"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            69..287
                     /locus_tag="OPY25_004089"
     CDS             69..287
                     /locus_tag="OPY25_004089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hin recombinase"
                     /protein_id="HCS0929554.1"
                     /translation="MECELIVERTSAGLEVVRSKGRIGGRRPKLTPEQWEQAGRLLAA
                     GETRHRVGLLFDVSISTLYKKFPVNQSR"
     gene            390..1562
                     /locus_tag="OPY25_004090"
     CDS             390..1562
                     /locus_tag="OPY25_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HCS0929555.1"
                     /translation="MAQDYHHGVRVVEINEGTRPITTVSTAIVGMVCTGDDADASVFP
                     INKPVLLTDVLTASGKAGESGTLARSLDAIADQAKPVTVVVRVAQGETEAETTSNIIG
                     GVTSDGKKTGMKALLSAQSQLGVKPRILGVPGHDTQAVATELLGVAQSLRGFAYLAAN
                     GCKTVEEAIAYRENFSQREGMLIWPDFINFDTVLKADATAYASARALGLRAKIDEQIG
                     WHKTLSNVGVNGVTGISADVFWDLQDPATDAGLLNKNDVTTLIRKDGFRFWGSRCLSD
                     DPLFAFENYTRTAQVLADTMAEAHMWAVDGVLNPSLARDIIEGLRAKMRSLVNQGYLI
                     GGDCWLDESVNDKDTLKAGKLTIDYDYTPVPPLENLMLRQRITDRYLVDFASRVAA"
     gene            1572..2087
                     /locus_tag="OPY25_004091"
     CDS             1572..2087
                     /locus_tag="OPY25_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HCS0929556.1"
                     /translation="MALPRKLKHLNLFNDGNNWQGIVESLTLPKFTRKFEKYRGGGMP
                     GAVDVDMGLDDGALDTEFSIGGTELLLFKQMGKATVDGIQLRFTGSIQRDDTGEVQAV
                     ELVVRGRHKEVDSGEWKTGESSSTKVSSTNSYAKLTINGEVLYEVDLVNMVEIVGGVD
                     LMEEHRNALGL"
     gene            2142..2444
                     /locus_tag="OPY25_004092"
     CDS             2142..2444
                     /locus_tag="OPY25_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HCS0929557.1"
                     /translation="MSDKLTEKTVKLDTPIMRGKTEITEIVLRKPQSGALRGTRLQAI
                     MDMDVGAMMTVIPRISSPTLTAQEMAELDPADLTAMAVEVVTFLLPKSVLADLPTT"
     gene            2459..2578
                     /locus_tag="OPY25_004093"
     CDS             2459..2578
                     /locus_tag="OPY25_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HCS0929558.1"
                     /translation="MADIATIFHWSPSITDVMPLTDVLEWRHKAIQRSGASDE"
     gene            2571..3179
                     /locus_tag="OPY25_004094"
                     /pseudo
     CDS             2571..3179
                     /locus_tag="OPY25_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134619.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            complement(3181..3591)
                     /locus_tag="OPY25_004095"
                     /pseudo
     CDS             complement(3181..3591)
                     /locus_tag="OPY25_004095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            4857..5399
                     /locus_tag="OPY25_004096"
     CDS             4857..5399
                     /locus_tag="OPY25_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HCS0929559.1"
                     /translation="MKVTWTVTPVGYQHIAKRCPSCNVKRDFTPSGAFRINSQKKILD
                     VWSIYKCTHCDYTWNIALYSRLPVSKINQELHHRLMTNDESTIRHFAYDTAVLKQNNA
                     KLSGQLDFRIQERCLTSITRQYQICVRIRLTRSFQVSLLSIMKIQLMLSSADIRRRID
                     SGQITGVTAKMLKSRKLRQT"
     gene            complement(5610..6251)
                     /locus_tag="OPY25_004097"
     CDS             complement(5610..6251)
                     /locus_tag="OPY25_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HCS0929560.1"
                     /translation="MGDIVTREQVASLITRYFSQQLSDDEKVAALNHFRLTLHELSPF
                     AREPVDLVLWVKASEVVANDYNPNVMAAGEKKLLQHSLQEDGFTQPVVVSEEKGQYLV
                     VDGFHRQLLGRRESGAGKRLKGWLPVTCINPERKGKAERIASTIRHNRARGKHQIASM
                     SDIVRDLARLGWADERIGKELGMDRDEVLRLKQISGLTELFEEEDFSPAWTVR"
     gene            complement(6236..7483)
                     /locus_tag="OPY25_004098"
     CDS             complement(6236..7483)
                     /locus_tag="OPY25_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001285496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HCS0929561.1"
                     /translation="MSDNVIMQRNQIQKIRTGEDVLSAVTGRVEWIFDTFSQVCLSFS
                     GGKDSTVLFHIAATIARRKHRRFSVLFIDWEAQYQCTIEHVQKMKDLYSDVTETFFWV
                     ALPLTTVNGVSQFQPEWVCWEPDVEWVRQPPTDAITDTTYFPFYRYAMTFEEFVPAFS
                     TWFTGNQCGVAILTGVRADESLNRFIGLTSQRKLRYADDKPWTTASPEGFYYTMCPLY
                     DWKARDIWIYHARTGAIYNPLYDLMYRAGVPLRNMRVCEPFGPEQRRGLWLYHVLEPE
                     TWARMCARVSGAASGAIYANESGAYFALRKRISRPAHHTWRSYAMFLLDVMPQKTAEH
                     YRNKIAVYLRWYQTHGYPEDIPDEQENDLGSRDIPSWRRICKTLIKNDFWCRTLSFSP
                     NKPRHYERYLECMKQRRKEWGIL"
BASE COUNT         1958 a         1940 c         1964 g         1839 t
ORIGIN      
        1 ttattttcca gaaactttca aaaaaagtcc ttttcgctca ggaggagcct tgccgttctg
       61 gcattgaaat ggagtgtgag ctgatcgttg agcgtaccag cgccgggttg gaagtggtgc
      121 gttcaaaagg tcgtattggt ggcaggcgtc caaagctcac cccggaacaa tgggagcagg
      181 ccggacggtt gcttgccgcc ggtgaaactc gtcatcgtgt tggattgctt tttgatgtta
      241 gcatttccac tctttacaag aaattccctg taaatcagtc gcgttgaaag tggcgatatt
      301 gtaccagcac tgacacatcg tgaaatacgt gcgccgcacg cctggcaacc agaacataag
      361 gtatccctgt caaccggaga gactgcctta tggctcagga ttaccaccac ggggtgcgcg
      421 ttgttgaaat caacgagggc acccgaccta ttaccacggt gagcactgcc atcgtgggca
      481 tggtctgcac cggcgatgat gctgatgcgt ccgtgttccc catcaataag cctgtcctgc
      541 tgactgatgt gctcaccgcc agcggtaaag cgggggagtc cggcacgctg gcccgctcgc
      601 tggacgcgat tgcagatcag gcaaaacccg tgactgtcgt tgtgcgtgtg gcgcagggcg
      661 aaaccgaagc ggaaaccacc tccaatatta tcggcggcgt aacttccgac ggtaagaaaa
      721 cgggcatgaa agcgctactg tcggcgcagt cgcagctcgg tgtcaagccg cgcattcttg
      781 gggtgccggg acatgacact caggccgttg ctactgaact gctgggcgtg gcgcaaagct
      841 tgcgcgggtt tgcctacctt gctgctaatg gctgcaaaac ggtggaggaa gctattgcct
      901 atcgcgagaa tttcagtcag cgcgagggaa tgctgatctg gcctgacttc atcaactttg
      961 acaccgtgct gaaagcagac gcgacggctt acgcctccgc ccgtgcgctc ggcctgcgtg
     1021 ccaaaatcga cgagcagatc ggctggcata aaaccctgtc caatgtgggt gtgaacggtg
     1081 tcaccggcat ttccgctgat gtgttctggg atctgcagga cccggcaacc gatgcgggac
     1141 tgctgaacaa aaatgacgtc accacattga tccgcaaaga cggcttccgc ttctgggggt
     1201 cccgttgtct cagtgacgat ccgctgtttg cctttgagaa ctacacccgc acggcgcagg
     1261 tgctggctga cactatggcg gaggcgcaca tgtgggcggt ggatggcgtg cttaatccgt
     1321 cgctggcccg cgacattatt gaaggactac gcgccaagat gcgcagtctg gtcaaccagg
     1381 gatacctgat tggtggtgac tgctggctgg atgagtctgt taacgataaa gacaccctta
     1441 aagccgggaa actgaccatc gattatgact acacgccggt gcctccgctt gaaaacctga
     1501 tgctgcgcca gcgcatcacc gatcgttacc tggtcgattt tgccagccgt gtcgctgcat
     1561 aagggggaat catggcttta ccacgcaagt taaaacacct gaacctgttc aacgacggga
     1621 acaactggca ggggatcgtt gagtccctga ccctgccgaa attcacccgc aagtttgaga
     1681 agtatcgcgg cggcggtatg ccgggcgcgg tggacgtaga catggggctg gatgacggcg
     1741 cactggacac ggaattttca atcggcggca ccgaactgct gttattcaag cagatgggca
     1801 aggcaaccgt tgacggcatc cagttgcgtt tcaccggttc cattcagcgt gacgataccg
     1861 gcgaagtgca ggccgttgag ctggttgtgc gcgggcgtca taaagaggtg gattccggcg
     1921 agtggaaaac cggcgagagc agcagcacca aagtcagcag taccaacagc tacgcgaagc
     1981 tgaccattaa tggtgaggtg ctctatgagg tcgatctggt caacatggta gaaatcgttg
     2041 gcggcgtgga cctgatggaa gaacaccgta atgccctcgg cctctgatta accttaacgg
     2101 cgcgggcagc cgcgccagta tttcattaac aggaaacgaa catgagcgac aagctgactg
     2161 aaaagaccgt aaaactggat acccccatca tgcgcggtaa aactgaaatt accgaaattg
     2221 tgctgcgcaa gcctcagtcc ggcgcgctgc gtggcacccg tctgcaggcc attatggata
     2281 tggacgtggg cgcgatgatg actgtgatcc cgcgaatctc ttccccgacg ctgaccgcgc
     2341 aggaaatggc agagctggac cccgccgatc tgacagcaat ggctgtagag gtggtgactt
     2401 ttttgttgcc gaagtcggtg cttgccgatt tgccgacaac ctgacggttg atgatctggt
     2461 ggcagacatt gccaccatct ttcactggtc gccgtccatc actgacgtta tgccgctgac
     2521 tgatgtgctg gagtggcggc ataaggcaat tcagagaagc ggggccagcg atgagtgata
     2581 ataacctgcg actgcaggta gttctggggg cggtggataa gttaacccgc ccatttaaaa
     2641 atgcacaggc tggctctaag gagctggcat cagctattag acaaacccgc gatcagatta
     2701 aaaagctgag tgatgctgga ggtcagctta aatctttcga tcagctaact caaagtgtta
     2761 gccgtactgg tgccgaactg gatcaggcga ggctacgcgc tcaaatgatg acgcgcgaaa
     2821 tgtcttcttt ggaatccccg acaaaaaaac aaacgcaggc gcttgaagct cagtggcgtg
     2881 ctgtttcacg tcttgaacaa aaacagcaac aggaaactcg ccagatggcg gcagccagag
     2941 ctgagcttta tcggctgggg ttatctgctg ggggcggagc gcgtgagacg gcacggattg
     3001 cacgagaaac tgagcggtat aaccgacagt tggctgagca ggagcgcagg ctgcgtgaag
     3061 ttggcgagcg tcagcgaaag ctcaacgcca tcaaagccaa ggctgaaaag acccgcgagt
     3121 taaggaactc tctggcaggt aatggtgcag gggcgatggc ggctggggta actactggca
     3181 ttccttaaat gccttttgaa attcttccgg gcttaacggt aattttgttc ccgacctgct
     3241 acttttttct aatccaagag ccttattact caggagcgga ttattcgggt ctgccagctt
     3301 ataacgtccc gccttattca aaacgccacg aatagcagcc cgctcattct gaattgtccg
     3361 cacggaaatc ccctgtgatt ttctgaactg gagatatccg gtgacatgac gtgttttaat
     3421 actgtcggta tgacgtagct taataccgtt atcacgaagg tagttcagaa agtatttcgc
     3481 gatacgcatg ctgtctgcag ccgtcgcgta tgccctgccg gcatcccggg ctaaggtcac
     3541 aaaatcgcga cggaatttct ccacttttga acgagctgtt ttccctgcca tattgccccc
     3601 tgtatgacac tggtgaaaaa agacacacta atccctcagc gcatcccatc agtcagaaca
     3661 cttgtcgata gttctcactc atgaaatgaa ctgtcataac cagctggaaa tattagtttt
     3721 tcgtcatcac agacgttccc tgcgtgtcgg tgcgttcgtc ttcctgactc gtctgatatt
     3781 gtgtagcagg gtagcgctat gttgagtttt tgcaggagtt caaccagtac gcagtacggc
     3841 gaatttaact ccccgtcagt aattactgac gcctcaatat catgacgata aaacctccat
     3901 taatcattac gttaagcttc acagatgaaa ccttaacaac gggttaaaca cgggccctga
     3961 gcggccgtcc gtggaaaacg gacgcgacgg gcgttgtaga aaacgttttt tcagcgcatt
     4021 cctcaaactg gtttcacgaa cgaatgcact ttttaaactg ttcggaagat caggaaatac
     4081 gtgctgaaga tgttttacgc cttgcggcgt cacttggttc tcgttttact cgaacgcaag
     4141 tgacgccgcg tatactcaaa ctgtccaatg catcgtccgg aagatgcccc aaatgttgcg
     4201 acgttcgtcg cgccaaatgg ctggcatacc cgtacatgca aaggttgtct gagcacggag
     4261 gcttaagaag tgagtactaa aagatacggt ataaaaccgt agaaagaaga agcgatcgtc
     4321 cactgttcgt gaagacaggt caaaaatctg ataccgaaaa acggtactta catgtagtaa
     4381 aaatatcttc gtcgcagaag tacacgacag ccgtttccaa agattaaagg gctgtaccac
     4441 ccgaaggcgc cacctctcag gctacggtga cattggtatg caatcacccg aaggcgcccc
     4501 tctcagatca ccggggcatt ggtgggtgca gctaatgcac cattacaacg ttcgtatagt
     4561 agatcattga tgccacgttg atcaatacaa ctcccccctg cttaaaaggc taaatatcat
     4621 attccgcttc atcaaaggca agcctgcggg ttacgacgcc aatattaatt taacgcatat
     4681 atctgaagaa gacttctttg atagtctgat cgtatcgctt cagtcgttga caggatggta
     4741 gtgttggaaa tcttttttta acccactgaa aaatatcttc tgattatttt tcacacacaa
     4801 atctctatgg tccgttccat acagatccgg ttttgtatgg gtaaaaaagg ttaattatga
     4861 aagtaacatg gactgtcact cctgtggggt atcagcacat cgcaaaacgc tgtccgtcat
     4921 gcaatgtaaa aagagacttc acgccgtcag gtgcattcag gattaattca caaaagaaaa
     4981 tactggacgt atggagtatc tataaatgta ctcactgcga ttacacctgg aatatagcgc
     5041 tgtattcccg ccttcctgta agcaaaataa atcaggaact tcatcaccgg ctgatgacaa
     5101 acgatgaatc cacaatcagg cattttgcct atgacactgc tgttctgaag caaaacaatg
     5161 caaaactatc aggtcaactt gatttccgta ttcaggagcg ctgtctgacc agtataacga
     5221 ggcaatatca gatatgtgtc cgaatcaggt taacccgctc tttccaggta agcctgctgt
     5281 ccataatgaa aatacaactt atgctgagtt cggcagatat caggaggcga atagactccg
     5341 ggcagataac tggcgttacg gcaaaaatgc ttaaatcgag aaagttaagg cagacttaat
     5401 attgtcttga gataacggag gaaacattct atgccagacg cagaattaag ttgatacagg
     5461 cttaataact tttaacctgc ttttataacc gggagaacag ggggcaaaat gccccctgtt
     5521 cttatacgga aatctttatt ggtaatcatt aaataataat tcaggtcacc ggccgaaata
     5581 gttttatttg cgataagatg ctgtccactt tagcgaaccg tccaggccgg actgaagtcc
     5641 tcttcttcaa ataattctgt cagtccactt atctgcttca gacgaagaac ttcatccctg
     5701 tccattccca gctccttgcc aatacgttca tctgcccatc cgagacgggc aaggtctctg
     5761 acaatatctg acatcgacgc tatctgatgc ttccctcggg cgcggttatg cctgatcgtc
     5821 gaggcaattc gttcagcctt cccctttcgt tcgggattga tacaggtgac gggcaaccag
     5881 cctttcaggc gttttcctgc tcctgactcg cgtctgccca gcaactgccg gtgaaaacca
     5941 tccacgacca ggtactgccc tttctcttca gatacaacga cgggctgggt aaagccgtcc
     6001 tcctgcagtg agtgctgcag caattttttc tctccggcag ccataacatt ggggttgtaa
     6061 tcgttggcca ccacttcgct ggctttcacc cacagcacca ggtccacagg ctcccgggca
     6121 aaggggctga gctcatgaag tgtcaggcga aaatgattga gggctgccac tttttcgtca
     6181 tctgaaagct gctgactgaa ataccgggta atgagactgg ccacctgttc cctggttaca
     6241 atatccccca ttccttcctc ctttgtttca tacactccag gtaacgttcg taatgccggg
     6301 gcttattagg actgaaagat aaggtccggc accagaagtc atttttaatc agtgtcttgc
     6361 atatcctacg ccaggaggga atatccctgc tgcccaggtc attctcctgt tcatccggaa
     6421 tatcttccgg ataaccgtgc gtctgatacc agcgcaggta taccgctatc ttgttccggt
     6481 aatgctcggc tgttttttgt ggcatgacat caagaagaaa catggcatag ctgcgccagg
     6541 tatgatgtgc tggtctggag atgcgtttgc gcagggcaaa ataagcgcca ctttcattag
     6601 cataaatggc cccgctggcc gctccggaga cgcgggcaca cattcgcgcc caggtctcag
     6661 gctccagtac atgataaagc cacagaccgc ggcgctgttc ggggccaaaa ggttcacaga
     6721 cccgcatatt ccgcaggggg acgccggctc tgtacatcag gtcatacagc gggttgtaaa
     6781 tggcgcccgt acgggcatgg taaatccaga tgtcccgggc tttccagtca tacagaggac
     6841 acatcgtgta ataaaacccc tcaggagagg cggtggtcca gggtttgtca tcggcataac
     6901 gaagctttcg ctggctggta aggcctataa acctgttaag ggactcatct gcacgaacgc
     6961 cagtcagtat ggccactcca cactgattgc ccgtgaacca agtcgaaaat gccgggacaa
     7021 actcttcaaa tgtcatggcg taacggtaaa aaggaaaata cgtcgtatca gtaatggcat
     7081 ctgtcggcgg ctgacgcacc cactccacat cgggctccca gcagacccat tctggctgaa
     7141 actgtgaaac accatttacc gtcgtcagcg ggagagccac ccagaaaaac gtctccgtca
     7201 catcactgta gagatccttc attttctgaa catgctcaat cgtgcactga tactgggctt
     7261 cccagtcaat aaaaaggaca gagaaacgcc ggtgtttcct gcgggctatt gtggcggcga
     7321 tatgaaacag aacggtggag tcttttccac ctgaaaaaga cagacaaacc tgagaaaagg
     7381 tatcaaatat ccactccaca cggcctgtaa ccgcagacag cacatcctcc ccggttctga
     7441 tcttctgtat ttgattacgt tgcataatga cgttatctga catgagtgtc tgaaaaccat
     7501 ctccctgcta tgttgaataa ttaccctgct aagcattagt tcagttgtta gtgaaatgac
     7561 aatattaaaa tgtgctttct taattatatt tgatctgtgc cccgaaaacg ggaatataaa
     7621 gaatggaaac cagagtttcc agtatgccac ttaatatatg cacaaggatg attccaaaca
     7681 ctttaataat taattttaac a
//
LOCUS       DAJVKX010000174         7579 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.174, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000174 DAJVKX010000000
VERSION     DAJVKX010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7579
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.174"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(53..478)
                     /gene="nudI"
                     /locus_tag="OPY25_004099"
     CDS             complement(53..478)
                     /gene="nudI"
                     /locus_tag="OPY25_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HCS0929562.1"
                     /translation="MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGE
                     RIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSAN
                     RDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL"
     gene            757..1299
                     /locus_tag="OPY25_004100"
     CDS             757..1299
                     /locus_tag="OPY25_004100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929563.1"
                     /translation="MKKSILLGFAGMLFVSASAQAISISGQAGEDYTNIGVGFGTEST
                     GLALSGNWMHNDDDGDAAGVGLGLNIPVGPLLATVGGKGIYTNPKDSDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIESYEEANAGARFTIMRPLSIEAGYRYLNLAGK
                     DGNRDNAIADGPYVGVNASF"
     gene            1414..2610
                     /locus_tag="OPY25_004101"
     CDS             1414..2610
                     /locus_tag="OPY25_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HCS0929564.1"
                     /translation="MLNVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGVPLSRRNTVG
                     DNLDSLVAILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHQAWLTEMER
                     YFQQRGRVMAPSNRKQAELPASAEFINNPVGTACGFALQLNRCLMFFTPGVPSEFKVM
                     VEKEILPRLRARFSLPEPPLCLRLTTFGRSESDLAQRLDSLPLPPGVTMGYRSSMPII
                     ELKLTGPATQREAMLALWPEVKRVAGQNLIFEGTENLPAQIARRLQERQLSLTLSEQY
                     TSGLLALQLSRAGAPVLASEVVPSQEETLAQTAHWTTERRSNHYAGLALAVSGLENEH
                     LNFALATPDGTYALRVRFSANRYSLAIRQEVCAMMALNMLRRWLNGEDITSEHGWIDV
                     VESLTS"
     gene            2860..3642
                     /locus_tag="OPY25_004102"
     CDS             2860..3642
                     /locus_tag="OPY25_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCS0929565.1"
                     /translation="MLESSKVPALTRAIDILNLIARIGPCSAAIIIETLRIPKSTAYL
                     LLNELKRQRFISLDHQENYCLWTKLVELSGHALSKMDLRELARPRLTQLMDEIGLLCH
                     LGIIDHENAYYILKVESSSTISVRSHEGKSLSLYRSGIGKCLLAWQPAAERKAIIEKM
                     VWERATLTTITEPQQLNDELERIRQRGWSFDNGEDYPDVRCVAAPVFNARNELTAAIS
                     LVGTRLQINEENLDYLAGKAIACAKDISRLLGWKSPFDSLAS"
     gene            3656..4861
                     /gene="rhmD"
                     /locus_tag="OPY25_004103"
     CDS             3656..4861
                     /gene="rhmD"
                     /locus_tag="OPY25_004103"
                     /EC_number="4.2.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HCS0929566.1"
                     /translation="MTLPKIKHVRAWFIGGATAEKGAGGGDYHDQGGNHWIDDHIATP
                     MSKYRDYEQSRQSFGINVLGTLIVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEG
                     KCVSDIKLIHDQMLGATMYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAV
                     RDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGPDFW
                     LMLDCWMSQDVNYATKLAHACAPFNLKWIEECLPPQQYEGYRELKRNAPAGMMVTSGE
                     HHGTLQSFRTLAETGIDIMQPDVGWCGGLTTLVEIAALAKSRGQLVVPHGSSVYSHHA
                     VITFTNTPFSEFLMTSPDCSTLRPQFDPILLDEPVPVNGRIHKSVLDKPGFGVELNRD
                     CHLKRPYSH"
     gene            4917..6206
                     /locus_tag="OPY25_004104"
     CDS             4917..6206
                     /locus_tag="OPY25_004104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929567.1"
                     /translation="MSITLLDGVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQI
                     DTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKFGARTWIGTTTLLWGFLSAAMAWAD
                     SEAKFLIIRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
                     GALLEMHGFMGHPGWFWMFVIEGLLAIGAGIFTFFWLDDTPQQARFLSLEEKNALIRQ
                     LASEEEKKVTSRLADALRNGRVWQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFT
                     ASVVTAVPWVAALLGTWLIPRYSDRTGDRRNVAAVTLLAAGIGIGLSGLVSPVLAILA
                     LCVAAVGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFA
                     SDAAGLLTLAGVAIIGSLIIFTLSVNRPVAQSGAAHH"
     gene            6232..7035
                     /gene="yfaU"
                     /locus_tag="OPY25_004105"
     CDS             6232..7035
                     /gene="yfaU"
                     /locus_tag="OPY25_004105"
                     /EC_number="4.1.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-L-rhamnonate aldolase"
                     /protein_id="HCS0929568.1"
                     /translation="MNALLSNPFKEGLRKRDTQIGLWLSSTTSYMAEIAATSGYDWLL
                     IDGEHAPNTVQDLYHQLQAIAPYASQPVIRPIEGSKALIKQVLDIGAQTLLIPMVDTA
                     EQARQVVSATRYPPLGQRGVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALEN
                     LDAILEVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIESCIYRIRAAGKAAGFLAV
                     DPAMAQKCLAWGANFVAVGVDTMLYTEALDSRLAMFKSVQSVSTAKRSY"
     gene            7041..7217
                     /locus_tag="OPY25_004106"
     CDS             7041..7217
                     /locus_tag="OPY25_004106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HCS0929569.1"
                     /translation="MPDGTYALRVRFSANRYSLAIRQEVCAMMALNMLRRWLNGEDIT
                     SEHGWIDVVESLTA"
     gene            complement(7304..>7579)
                     /gene="sseL"
                     /locus_tag="OPY25_004107"
     CDS             complement(7304..>7579)
                     /gene="sseL"
                     /locus_tag="OPY25_004107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector
                     deubiquitinase SseL"
                     /protein_id="HCS0929570.1"
                     /translation="NTKQEIIEAAKIAGISENEDIDFIETNLQNNVPNGCGLFCYHTI
                     QLLSNAGQNDPATTLREFAENFLTLSVEEQTLFNTQTRRQIYEYSLQ"
BASE COUNT         1704 a         1821 c         2113 g         1941 t
ORIGIN      
        1 ccggctagcc gcatgttaaa agcgtaaaga cagcctgaag cggctgtcgt tattataata
       61 accctttcaa tgctaatgtg tggcgtgtcg ctacattcaa atcatacagc gccagttctt
      121 ctggcttgac ccaggcgtag tcctgaaatt cgtcgttaat acatatatcg cggttagcgg
      181 aaacacagtc gaagatgaga taaatcatat aaatctcttc ttgtctgcca tcagcgtacg
      241 ttttaacgcg gatatcgtcg cgaaaggtcc acggcgtaat atcgctcaga atcagttgtt
      301 cgccgagttc ctcccgaatc tcccgacgca gcgcctcttc aatacgttcg cctggctcga
      361 ccccgccgcc cgacagcgcc cactgaccgg gaaagacgcc gcggttgtcg gccattttgc
      421 acagcagata acagccatca ttttgaatta atgggcaaac tatagttcgt tgacgcataa
      481 gtcgcttcct taaaccacca ggccatcagc ttaacaaatc attctgcgaa attctttgtg
      541 aaaaatggaa gcgataacgc agactgcgtt ttttgttaat tttgttgatg caggcgtcgc
      601 catgtgatgg cgcaatgatg cgtcacggcg aaagtagtat ttcgttacaa tatgtttttg
      661 gaatggtttc ttagtgcatt gattcctcag cgtctggcag tacaattctg ccgttttggg
      721 gagtttttct ttatgtgctt gctggaaagg gtaaaaatga aaaaaagcat attattaggt
      781 tttgccggaa tgctgttcgt ttctgcatcg gcgcaggcca tcagtattag cggccaggcg
      841 ggcgaagatt acaccaacat tggcgtgggt tttggtacgg aatcgacggg actggcgcta
      901 agcggcaact ggatgcacaa cgatgatgat ggcgacgctg cgggcgtggg tctggggctg
      961 aacattccgg tgggaccgct gctggcgacg gtaggcggta aaggtattta taccaatccg
     1021 aaagacagcg atgaaggcta tgcggcggct gtcggcggtg ggttacaatg gaaaatcggc
     1081 aacagcttcc gtctgttcgg cgagtattat tattcaccag attcgctgtc cagcggtatc
     1141 gaaagttatg aagaagcgaa tgcaggcgcg cgtttcacca ttatgcgccc gctgagcatt
     1201 gaagccggtt atcgttacct gaacctggcg ggtaaagacg gcaaccgcga caatgcgatt
     1261 gctgacggcc cttatgttgg cgtaaacgcc agtttttgat gctaacggcg cggcaatcgt
     1321 cgcgccatat tcctcctttt cccgtcattc ttctttccac gtcatattcg tctttgcgtt
     1381 atagtgtttt catcataaaa gcaggagaac acaatgctaa atgtggaaat gctatccacc
     1441 ggggatgagg tgttgcacgg acaaatcgtt gacaccaatg ccgcctggct ggctgatttt
     1501 ttctttcatc agggcgttcc gttatcacgg cgaaatacgg taggcgataa tctggacagt
     1561 ctggtcgcta tcttgcgtga acgcagtcaa catgctgatg ttttgattgt taatggcggg
     1621 ttagggccga ccagcgatga tttaagcgcg ctcgccgcgg caacggcaaa aggcgaagga
     1681 ttagtactgc accaggcgtg gctgaccgaa atggaacgtt actttcagca gcgtggtcgc
     1741 gtgatggcgc cgagcaaccg taaacaggcg gaactgcctg ccagcgcgga gtttattaat
     1801 aatccggtcg gcactgcctg tggatttgcg ctacagctca accgctgcct gatgtttttc
     1861 acccccggcg taccgtcgga atttaaggtt atggtggaga aggaaatctt accgcggtta
     1921 cgcgcgcgtt tttcgctgcc ggagccgccg ctttgcctgc ggttaacgac ttttggacgt
     1981 tcagaaagtg acctcgcgca gcgtctcgat tcactgccgt tgccgcccgg cgtgacgatg
     2041 gggtatcgct catcaatgcc gatcattgaa ctgaaattga ccggcccggc gacgcaacgg
     2101 gaggcgatgc tggcgttatg gccagaggtc aaacgggtcg ccggacagaa cctgattttt
     2161 gaaggtacgg aaaatctgcc ggcgcaaata gcccgccgcc tgcaggaaag gcagttgagt
     2221 ctgacgttga gcgagcaata caccagcggt ttactggcgc tacagctttc ccgtgccggg
     2281 gcgccggttc ttgccagcga agtcgttcct tctcaggaag agacgctggc gcaaacggca
     2341 cactggacga cagaacggcg cagcaatcat tatgccggtc tggcgctggc cgtgtcgggg
     2401 ctggaaaacg aacatcttaa tttcgcgctg gcgacgccgg atggcacgta tgccttacgc
     2461 gtgcgtttta gcgccaatcg gtatagtctg gcaatacgtc aggaggtctg cgcgatgatg
     2521 gcgctaaata tgctgcgccg ttggcttaat ggcgaggaca ttaccagcga gcatggctgg
     2581 atagacgtgg ttgaatcatt gacatcataa tccctttctc ttatctgcga tgggaacgac
     2641 atcgtgagcc ggataaggcc gctatgccat tatccggcaa tattatctgc ttttttgtcc
     2701 agccaattgt actgaataca aagtaatacg tgcgttaatt cacatttata tggttaaccc
     2761 ttccactccg ttggaaggcg gataagcttt gacgcgcttc acaatttttt ccctactgac
     2821 ctttcacact gattccagtg tctcagactg gagtccaata tgttggaatc aagtaaagtc
     2881 ccggctctta ctcgcgcaat cgacatcctc aatttgatcg cgcgtattgg cccatgcagc
     2941 gcggcaatca ttattgaaac gttgcgtatt ccaaaaagca ccgcgtacct gctgttgaat
     3001 gaattaaaac gtcagcgatt tattagcctc gatcatcagg agaactactg cctgtggact
     3061 aagctcgttg aattgtcggg tcatgcgctc agcaagatgg atctgaggga gctggcgcgt
     3121 cctcgtctaa cacaactgat ggatgaaatc gggctgctgt gtcacttggg gatcatcgac
     3181 cacgaaaatg cgtattacat actgaaagtg gaatcctcat ccactatcag cgtgcgctcg
     3241 catgagggga aaagcctctc tctttatcgt tccggcatcg gcaaatgcct gctggcatgg
     3301 cagccggccg ccgaacgcaa agccattatt gaaaaaatgg tatgggagcg agccacgctg
     3361 accaccatca ccgagccgca acaattgaat gatgagctgg aacgcattcg ccagcgtgga
     3421 tggagctttg ataacgggga ggattatccg gatgtccgct gcgttgccgc accggtattt
     3481 aatgccagaa acgaactgac cgcggcaatt tcactggtcg gcacgcgcct gcaaatcaac
     3541 gaagagaatc ttgattattt ggccggtaaa gctattgcct gtgccaaaga tatttcacgc
     3601 ctgttgggat ggaaaagtcc cttcgactca ctcgcatctt aaaatggaga atattatgac
     3661 tcttcctaaa attaaacacg ttcgagcctg gtttattggg ggcgctaccg cagagaaagg
     3721 ggctggcggc ggggattatc acgaccaggg aggaaatcac tggattgatg accatatcgc
     3781 cactcccatg agcaaatatc gcgactatga gcagtctcgt cagtcttttg ggatcaacgt
     3841 gttagggacg ctgattgtcg aagtagaggc ggaaaatggg cagacggggt tcgccgtttc
     3901 gacagcaggg gagatgggct gttttatcgt agaaaaacat cttaaccggt ttattgaagg
     3961 caaatgcgta agcgatatca aacttattca cgatcagatg ctcggcgcga ccatgtacta
     4021 ctccggttcc ggcggtctgg tgatgaacac gatttcctgt gtggatctgg cgctgtggga
     4081 tctgtttggc aaggtggttg ggctgccggt ttataaattg ctgggcggag cggtacgcga
     4141 tgaaattcag ttttacgcca ccggcgcacg cccggatctg gctaaagaaa tgggctttat
     4201 cggcggtaaa atgccgactc actggggacc gcacgatggt gatgcgggga tccgtaaaga
     4261 tgccgcgatg gtggcggata tgcgtgaaaa gtgcgggccg gatttctggc tgatgctcga
     4321 ctgctggatg agtcaggatg tgaactatgc gactaaactg gctcacgcct gtgcgccatt
     4381 taatctcaaa tggattgaag agtgtctgcc gccgcagcag tatgaaggct atcgcgaatt
     4441 aaaacgcaac gcgcctgcag ggatgatggt taccagcggc gaacaccatg gtacgctgca
     4501 atccttccgc actctggcag aaaccggcat tgatattatg cagccggatg ttggctggtg
     4561 cggcggatta accacgctgg ttgagatcgc cgcgcttgcc aaatcgcgcg ggcaactggt
     4621 ggtgccgcac ggttcgtctg tctattcgca ccatgcagtt attactttca ctaatacccc
     4681 tttcagcgag ttcctgatga ccagcccgga ctgctccacc ctgcgtccgc aatttgaccc
     4741 gattctcctg gatgagccgg tgccggtgaa tggacgcatc cataaatcag tgctggataa
     4801 gccgggcttc ggcgtcgagc ttaaccgtga ctgtcacttg aaacgccctt atagccacta
     4861 ataactcgtg cgttgccttt gtacggcaac gccctcatcc tgttgaggat attgctatga
     4921 gcatcacttt acttgacggc gtagtgaaga aaaaccgcgc acgtttaatt ccttttatgt
     4981 tggcgctgta cgtactggcg tttctggatc gttcaaatat tggttttgcc aaagagacct
     5041 atcagataga taccgggcta agtaatgaag cctacgcgct aggggccggt attttctttg
     5101 tggtttacgc tttccttggc gtaccggcta acctgctgat gcgcaaattt ggcgcaagaa
     5161 cctggatcgg cacgactacc ctgctgtggg gctttctctc tgctgcgatg gcctgggcgg
     5221 atagtgaagc aaaatttctg ataatccgca cgctattggg cgcggcggag gctggatttt
     5281 tccccggcat gatctatcta acttcacaat ggttcccgca gcgtaaccgt gccagcatta
     5341 tggggctatt ttatatgggc gcgccgctgg cgttaacgtt gggttcgccg ctctccggcg
     5401 ctctgctgga gatgcatggt tttatggggc acccgggatg gttctggatg ttcgttatcg
     5461 aaggcctact ggcgattggc gcagggatat tcaccttttt ctggcttgat gacactccgc
     5521 agcaggcgcg ttttcttagc ctggaagaaa agaacgcgct tatcaggcaa ctggcgagcg
     5581 aagaagagaa aaaggtcacg tcaaggcttg cggatgcgct gcgtaatgga cgcgtctggc
     5641 aactggctat tatttatctg acgattcagg tggcggtata cggactcatc tttttcctgc
     5701 cgacccaggt tgccgcgcta ttgggcacta aagtgggctt taccgcttcg gtggtaacag
     5761 cggttccctg ggtggcggct ttgcttggca catggcttat tcctcgctac tccgaccgta
     5821 ccggcgatcg ccgtaacgtt gcggcagtga cgctactggc tgcgggcatt ggcattggcc
     5881 tgtcaggtct ggtttctccg gtgctcgcta ttctggcgct ctgtgttgca gcagtaggat
     5941 ttattgccgt tcagcccgta ttctggacca tgccaacgca gctactttcc ggtacggctc
     6001 tggcggcagg aattggtttc gttaatctgt ttggcgctgt gggcggtttt attgccccaa
     6061 ttctgcgcgt aaaagcggaa acgttgtttg ccagcgatgc ggcgggcctg ctgacgctgg
     6121 ccggagtcgc catcattggc tcattaatta tcttcacgct gagcgttaat cgtccggtgg
     6181 cgcaatccgg cgctgcgcat cattaatctt atctacgttg taaggatcgc tatgaacgca
     6241 ttgttatcaa atccttttaa agaaggatta cgtaaaaggg atacgcaaat tggtttgtgg
     6301 ctcagttcaa ccacctctta tatggcggag attgcggcga cgtcgggtta tgactggttg
     6361 ttaatagatg gcgagcacgc gcctaatacg gtgcaggact tgtatcatca gttacaggcc
     6421 atcgccccat acgccagcca gccggtgatt cgcccgatcg agggaagtaa agcgctcatt
     6481 aaacaggtac tggacatcgg ggcgcaaacg ctactgatcc cgatggttga caccgcagaa
     6541 caggcgcgcc aggtcgtttc cgctacccga tacccgccgt tggggcaacg aggcgttggc
     6601 gcgagcgtgg cgcgtgcggc gcgctggggg agaatcgaca actatatggc acaggccaat
     6661 gagtcgctct gcctgttggt gcaggttgaa agcaaagtgg cgctggaaaa ccttgacgcg
     6721 attctggagg ttgaaggcat tgatggcgtc tttatcggtc cggcagatct ctctgcttca
     6781 ttgggttacc ccgataatgc cggacacccg gaagtgcagc gaatcattga atcgtgtatt
     6841 tatcgtattc gcgccgccgg aaaagcggcg ggttttttgg cggtcgatcc ggcaatggcg
     6901 cagaaatgtc tggcgtgggg cgcgaatttt gtcgcggtcg gggtagatac gatgctctac
     6961 accgaggcgc tggacagcag gttggcgatg tttaaatctg ttcagtcagt aagcacggca
     7021 aaacgtagtt attgagaaaa atgccggatg gcacgtatgc cttacgcgta cgttttagcg
     7081 ccaatcggta tagcctggca atacgtcagg aggtctgcgc gatgatggcg ctaaatatgc
     7141 tgcgccgttg gcttaatggc gaggacatta ccagcgagca tggctggata gacgtggttg
     7201 aatcattgac ggcatagaac ttttagtggg aaggcttggc cttcccatcc ttatatactt
     7261 ataaattctt ggcagagcat catttcagga taagtactcg ccattactgg agactgtatt
     7321 catatatttg tcgccgggtt tgggtgttaa atagtgtttg ttcctctact gaaagcgtta
     7381 agaaattttc cgcaaattct cgtagtgtgg tagcaggatc gttttgtcct gcattcgata
     7441 agagttgaat tgtatggtaa caaaatagac cacagccgtt gggtacatta ttttgtaaat
     7501 tggtttcaat aaaatcaata tcttcgtttt ctgatatgcc tgcaattttt gctgcttcta
     7561 taatctcttg cttagtatt
//
LOCUS       DAJVKX010000175         7383 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.175, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000175 DAJVKX010000000
VERSION     DAJVKX010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7383
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.175"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            76..663
                     /locus_tag="OPY25_004108"
                     /pseudo
     CDS             76..663
                     /locus_tag="OPY25_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466162.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
     gene            747..3443
                     /locus_tag="OPY25_004109"
     CDS             747..3443
                     /locus_tag="OPY25_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HCS0929571.1"
                     /translation="MNNTWKSVLCPIACGVGMLLSASPYSASGKDIEFNTDFLDVKNR
                     DNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVT
                     QLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDW
                     DPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQAS
                     YDHRDDDESTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVVS
                     DDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTL
                     HVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASW
                     GVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQ
                     GNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVT
                     YNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYN
                     GDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQSA
                     QADGYYSHQGALTDIDLSADYEEGSYRSLSMSLRGGMTLTTQGGALHRGSLAGSTRLL
                     VDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQ
                     ITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWL
                     AGVKAGETLKVFWDGAAQCEASLPPTFTPELLANALLLPCKMLEGQPPTAPQKSSPLP
                     AQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME"
     gene            3456..4229
                     /locus_tag="OPY25_004110"
     CDS             3456..4229
                     /locus_tag="OPY25_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HCS0929572.1"
                     /translation="MNKTNHFNRQALIATVLLAAPLVSHSAIVPDRTRVIFNGNENSI
                     TVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAAG
                     LPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAIARQVDKTHPWQTKLT
                     LTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSP
                     VVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK"
     gene            4249..4755
                     /locus_tag="OPY25_004111"
     CDS             4249..4755
                     /locus_tag="OPY25_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0929573.1"
                     /translation="MTMLTRWKILVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCT
                     VGGASVEFGDVLTTKVGDVSQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQT
                     SVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNAS
                     ATLVVDYQ"
     gene            4770..5240
                     /locus_tag="OPY25_004112"
     CDS             4770..5240
                     /locus_tag="OPY25_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006667202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0929574.1"
                     /translation="MKRVLILTLLITRFACADNLTFHGKLINPPACTINNGETLEVSF
                     GSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTNVPGLG
                     IELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ"
     gene            5237..5773
                     /locus_tag="OPY25_004113"
     CDS             5237..5773
                     /locus_tag="OPY25_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCS0929575.1"
                     /translation="MNRIFQTTGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNL
                     VVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVVVTFQGVEDSTL
                     PGLLALESSSIANGFAIGIETADQHPLIINASQGTEFMLAEGNTIINLQAWLQKTSGE
                     NIMPGEFNASAMVNFEYQ"
     gene            5832..6950
                     /locus_tag="OPY25_004114"
     CDS             5832..6950
                     /locus_tag="OPY25_004114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929576.1"
                     /translation="MEIKKSILVRKNIRLSGIIIDMLILTILLISTFDAVSDSSPVKA
                     SAINIALQGTPNTDYELNGDLRSNGGIMPKTLYMVCSGGKFSASQADCVAGQWVDIEV
                     VISADSHTFMNLTNMGNLSSSAFQEKRRARCTAKNSNTMDCIWESNFDINLFFSPSTN
                     ISSIERQSLTLHIEPTNNASPSLQQINISGDLIYQPSDYAVYNQGYTPDVLAYVNFYA
                     KYNIVQSSFGTQTGPATGALPGRLNLNGNVATTVSLYPEQLDASFSKTEFSITSASKE
                     FTGSGNNELLAEIYLNYGLQHCQPQTADSICGQILANANVSTSCGDHNITITTNMCNT
                     GNDQCDSDETWKIAEIFGTWGRVNVDTICAITVLLPYE"
BASE COUNT         1978 a         1871 c         1843 g         1691 t
ORIGIN      
        1 tggctctatg ccgcatatcc cttgatatac gcgtacaaaa tgctgccata aaacacgtta
       61 attaaggata acacgatgaa gtcatctcat ttttgtaaac tggcagtaac tgcatcttta
      121 gttatgggaa ttgtctccgg cgctcaagcc gcgggtagca acacagcaaa ggttactttc
      181 cttggtaata ttgttgattc cccctgctct gtcacattgg atacggaaga tcaaacagtc
      241 aatatgggct caagtatcgg taatggcacg ctgagtaatg gtaaaacgac catcaacaat
      301 gcccgtacct ttcatatcga tcttgagggt tgtacctagg ctaccgagaa aaatatgaat
      361 gtggtattca ctacaggtag tggaaccaca gcggctacag gcgccacgga taatctcgcg
      421 ctgatgaaga ctgacggcac tggcgctatt agcaacataa gcctggcaat cggcgatgca
      481 ggcaaaaaca atatcaaact gggcgatacc tatacacagg ccattgcgga cctggacaga
      541 gataccatcc ttgatgagaa gcaaagcctg aatttcaccg cctggctggt tggcgcagca
      601 accggcaccg taggcacagg tgaattcagc agcgccgcca acgtcactat ctcttacctg
      661 taattcagat aacagagtca cgacgataaa taccctgccg ctttaggtag ggtattcctg
      721 ttgagtttta ttgcggaata tatttgatga ataacacatg gaaaagtgtt ctttgcccaa
      781 tagcgtgtgg agtgggaatg cttctaagcg cctcccctta tagcgcgtca ggcaaagaca
      841 tcgaatttaa taccgatttc ctcgatgtaa aaaatcgcga taacgtcaac attgcacagt
      901 tttctcgtaa gggttttatc ctgccaggcg tctacctttt acaaattaaa attaacggac
      961 agactctgcc gcaggaattt cctgttaact gggttattcc agaacatgat ccacaaggaa
     1021 gtgaggtttg cgcagaacca gaattagtta cgcaattggg tataaagccg gaactcgcgg
     1081 aaaaactcgt ctggataacg cacggtgaac gacaatgtct ggcgccagat tcactgaaag
     1141 gcatggattt tcaggctgac ctgggacact ccacgctgct ggtgaattta ccccaggcgt
     1201 atatggaata cagcgatgtc gactgggacc cacccgcccg ctgggataat ggtattcccg
     1261 gcatcattct ggattacaac attaataatc agctccgcca cgatcaagaa agcggcagcg
     1321 aagagcaaag catcagcggc aacgggacgt taggcgcgaa cctgggcgca tggcgactac
     1381 gggccgactg gcaggccagc tacgaccatc gtgacgatga cgagagcact tccaccctcc
     1441 acgatcagag ctggagccgc tactacgcct atcgcgcact accgacgctc ggggccaaac
     1501 ttacgctggg cgaaagctat ctccagtccg atgttttcga cagctttaac tatatcggtg
     1561 ccagcgtcgt ttctgacgat cagatgctgc cgccgaaact gcgcggctat gcgccggaga
     1621 tcgtgggcat tgcgcgctct aatgcaaaag tcaaagtctc ctggcagggg cgcgtactgt
     1681 atgaaacgca ggtgcccgca ggaccgttcc gtattcagga tctcaaccag tccgtttccg
     1741 gtacgttgca cgtcaccgtg gaagagcaga acggtcagac ccaggagttt gacgttaaca
     1801 ccgcatcggt tcccttcctg acgcgccccg gcatggtgcg ctacaagatg gcgctgggcc
     1861 gcccgcagga ctgggatcat caccctatta ccggcacatt cgcctcggcg gaggcttcgt
     1921 ggggggtcac caacggctgg tcgctctatg gcggcgcaat tggagaaagc aactatcagg
     1981 ccgtggcgct gggaagcggt aaggatcttg gcgtggtggg cgcggtggcg gtggacatta
     2041 cgcactccat cgcccacatg ccgcaagacg acgggtttga cggcgaaacg ctgcagggta
     2101 actcatatcg catcagctac tcccgtgact ttgatgaaat cgacagccga ctaacctttg
     2161 ccggataccg cttctcagaa aagaacttta tgagcatgag cgactatctg gatgcgaaaa
     2221 cctatcatca tctcaatgcc ggtcacgaaa aagaacgcta tacggtcacc tataaccaga
     2281 acttccgtga acagggcatg agcgcctatt tcagctactc acgcagtacc ttctgggaca
     2341 gcccggatca gagtaactat aacctgtctc tttcctggta cttcgactta gggtcgataa
     2401 aaaatctcag tgcgtcgctg aacggctatc gcagcgaata taacggtgat aaagatgatg
     2461 gcgtctatat ctcgctgtct gttccctggg gcaatgattc catcagctac aacggtacgt
     2521 ttaacggtag tcaacaccgt aatcagctcg gctattccgg ccacagccag aacggcgata
     2581 actggcagct tcacgtcggg caggatgaac aaagcgcgca ggcagacggt tattacagcc
     2641 atcagggcgc gctgacggac atcgatctga gcgcggatta tgaagaagga tcgtaccgtt
     2701 cgctgagtat gtcgctgcgc ggcggcatga cgctgaccac ccagggcggc gcgctacacc
     2761 ggggaagttt agcgggcagc acacgtttgc tggttgatac cgacggcatt gcggacgtcc
     2821 ccgttagcgg taacggctcg ccaacctcaa ccaacatttt cggcaaggcc gtgattgcgg
     2881 atgtcggaag ctattcgcgc agcctggcgc gtatcgatct gaacaaattg ccggagaagg
     2941 cggaagctac taagtcggtt gtgcagatca cgctcaccga aggcgccatc ggctaccgtc
     3001 actttgacgt ggtcagcggc gagaaaatga tggcggtttt ccggctagca gacggcgact
     3061 tcccaccttt cggcgccgaa gtgaaaaacg agcgccagca gcagttgggc ctggtggccg
     3121 atgacggcaa cgcctggctg gcgggcgtaa aagccgggga aacattgaaa gtcttctggg
     3181 atggcgcggc gcagtgtgaa gcatcactcc cgcccacgtt tacaccagag ctattggcca
     3241 acgcgctatt gctgccgtgc aaaatgctgg aaggtcagcc ccccaccgca ccgcagaaaa
     3301 gttctccgct gcctgcgcaa ccgctaatcc aggaacatac gcaaaccgat ggccaaccgg
     3361 ccgcgccggt ggcgacaacc actcaaaccc cgcccatacc gctggctgac aaccatgcgg
     3421 tgaatcgcaa ggatatggaa taaagggaac ctgtaatgaa caagaccaac cattttaatc
     3481 gccaggcgct tattgccacg gtattactgg ctgcgccgct ggtgtcacac agcgcgattg
     3541 tgccggatcg tacccgcgtt atttttaacg gcaatgaaaa ttcaatcacc gtcacgctga
     3601 aaaacggcaa cgccactctg ccctatctcg ctcaggcgtg gctggaagac gataagttcg
     3661 ccaaagatac ccgctatttt accgccctgc cgccgctgca gcgtattgag ccaaaatccg
     3721 acgggcaggt taaagtccag ccgttaccag ccgcggctgg cctaccgcag gaccgggaaa
     3781 gtctgtttta tttcaacgtg cgagaaattc cgccgaaaag cgataagcct aatacgctcc
     3841 agctggcgct gcaaacgcgt attaagtttt tctaccgccc ggtagccata gcccggcagg
     3901 tggataagac gcacccgtgg cagacgaagc tcacgctgac ctaccagggc gatggtgtga
     3961 tcttcgacaa ccccacaccg ttttacctcg tcatcagcaa tgccggtagc aaagagaacg
     4021 agaccgcctc cggctttaaa aacctgctga ttgccccgcg tgaaaaagtg acctctccca
     4081 tcaaaggtgc ctcgctcggc agctcaccgg tggtgggcta cgtcgatgat tacggcggcc
     4141 atcgcctgct ggtttttacc tgctcaggga atacctgcaa ggtcaatgag gaaaaaaccc
     4201 gtgacgctga gaagaaagcg aataagtaat cctgtgcgaa agagatctat gacgatgttg
     4261 actcgctgga aaatactggt gctgctgtgc ggtggattcg ttaccggcac cgaggctgcc
     4321 ggcacaaaaa ccgtgcaact ggagctgcat ctggtcgtca ctcaaccacc gccctgtacg
     4381 gtaggcggcg cttccgtaga gtttggcgat gtcctgacca ccaaagttgg cgatgtttct
     4441 caaacgaaac ctgtgggcta cagcctgaac tgcgatggca gagcgagtga ctatctgaag
     4501 ctacaaattc aggggaccac caccaccatc agcggggagc aggttctgca aacttcggtg
     4561 caggggttag gcatccgtat tcagcaggcg ggcaataagc aactggttcc ggttggcata
     4621 acggattggc tgaacttcac cctgagcggc agcaatgggc cggagctgga agccgtaccg
     4681 gttaaagagc ccaccacgca gttagcgggt ggcgatttta acgccagtgc gacgttagtc
     4741 gtggattacc agtgatggag agattcatag tgaaaagggt gcttatcctg acgcttttaa
     4801 tcacccggtt tgcctgcgcc gacaatttga cctttcacgg caaactgata aacccgcccg
     4861 cctgtactat caataatggt gaaacgctgg aggtcagttt tggtagcgtg attattgata
     4921 atattgacgg cgtcaattac ctgaccgaga tcccgtggac ccttacctgc gacagcagct
     4981 ttcgcgatga cgcattaact tttacgttga gctatctggg cacggcgacg ccttactccg
     5041 caaaagcctt aaccaccaat gtccctgggc tgggcattga acttcagcag aacggcacgg
     5101 tgtttcctcc cggcacgtcg ctaaccatca atgagtcatc gcttcccaca ctaaaagccg
     5161 tgccggtaaa acagcccggt aaagagcctg ccgaaggcga ttttgaagct tttgccacgt
     5221 tacaggtgga ttaccaatga accgtatttt tcaaactacc gggcatttga tcggaggcgt
     5281 aatgttatgg gcggtttgca atacgctacc tgctgccacg cctaatgtgc actacagcgg
     5341 taagctggtt gccggagcct gtaacctggt agtggataat gacacgatgg cgacggtgga
     5401 ttttcatact attggcagtg acaatttcga cgccagcggg caaacgactc ctgttccatt
     5461 cacacttagc ctccaggatt gcaaaacagc gctagccaac ggcgtggtgg tgacctttca
     5521 gggtgttgaa gacagtaccc tgcccggact gctggcgctc gaatcgtctt ctattgctaa
     5581 cggttttgct atagggattg agaccgcaga tcagcacccg ttaattatca acgcttctca
     5641 aggtacggaa tttatgttgg cagagggaaa taccattatc aatctccagg catggctaca
     5701 aaaaacatca ggggaaaata ttatgcctgg ggaatttaac gccagcgcaa tggttaattt
     5761 tgaataccaa taatgttatt taacaaaaag gcattgatgc tctggccaga ataaaaagga
     5821 gttacaacgc aatggaaata aaaaaaagca tcttggttag aaaaaatata cgcttgtcag
     5881 gaatcatcat tgacatgctc attttaacca tacttttaat cagcacgttt gatgctgtat
     5941 ctgactcttc cccggtaaaa gcaagcgcta tcaatattgc acttcaagga actcccaaca
     6001 cagattatga attaaatggc gatctccgct ctaacggagg gataatgcca aagacgcttt
     6061 atatggtatg ttcaggagga aaattcagtg caagccaggc tgattgcgtt gccggtcaat
     6121 gggtagatat cgaagttgta atatctgcgg acagtcatac gttcatgaat ttgacaaata
     6181 tgggcaattt gagttcttct gcatttcagg aaaaaaggcg tgctcgctgt acagcgaaaa
     6241 atagtaatac gatggattgt atttgggaaa gtaacttcga cattaacttg tttttttcac
     6301 cttctacaaa catctcctca attgaaagac aatctctgac tctccatatc gagcctacga
     6361 ataatgcatc accttctcta cagcaaatca atatcagcgg cgacttaatc taccagcctt
     6421 ctgactacgc agtgtataat caaggatata ctcctgacgt cttagcctac gttaattttt
     6481 atgctaaata caatatcgtc caatcaagct ttggtacaca gacaggcccg gcgacgggcg
     6541 ccctgccggg acgcctcaat ctgaacggga acgtagcgac cacagtttct ttatatcctg
     6601 aacaacttga tgcctctttt tcgaaaacag aattttccat cacatctgcc agcaaagaat
     6661 ttacgggttc tggtaataat gaactactgg cagaaatcta tctaaactat ggactacagc
     6721 attgccagcc gcaaacggca gatagtattt gtggtcaaat attagctaac gcgaacgttt
     6781 caacatcgtg tggtgatcat aatattacta tcacaaccaa tatgtgcaat acaggtaatg
     6841 accaatgtga tagtgatgaa acatggaaaa ttgcagagat cttcgggaca tggggccggg
     6901 ttaatgtcga cactatatgc gctattacag tattgcttcc ctatgaataa tgcttagaaa
     6961 aaatactcgg aaccctaaat aatctcgcaa aacagtagat tacttatccg aaaaattttt
     7021 cggccttcag tgaggggctc tgctccagtt gcgcgatcag atcatttaac caaaataata
     7081 gtcgaacaaa agaggcgagc catgaacggc taccatttct ttcgcgagtt aagcgaagaa
     7141 tgctgaaaaa acagtacaga aaagtcagga taaagagtta tacagacggc ttaccactat
     7201 cccaatgctg tatacaggat tattggttag ttcactttac tgctcctaaa aaacctgcct
     7261 cacttaaaat ttagcaaaat tattgaccaa ggaaaacaaa tgtgtacaaa ttttttaaaa
     7321 acatcgctac taataacatc cactttttgg tgtattgcgc tacaatgcgc tgaagtaaga
     7381 acg
//
LOCUS       DAJVKX010000176         7017 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.176, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000176 DAJVKX010000000
VERSION     DAJVKX010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7017
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.176"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(186..1265)
                     /gene="fbaA"
                     /locus_tag="OPY25_004115"
     CDS             complement(186..1265)
                     /gene="fbaA"
                     /locus_tag="OPY25_004115"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HCS0929577.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKTDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLHENIEICSK
                     YLARMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQDYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKENEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFKELNAIDVL"
     gene            complement(1367..2530)
                     /gene="pgk"
                     /locus_tag="OPY25_004116"
     CDS             complement(1367..2530)
                     /gene="pgk"
                     /locus_tag="OPY25_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCS0929578.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKEGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDEALSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFVAAQGHSVGKSLYEADLVDEAKRLLTTCDIPVPTDVRVATEFSETAPATLKSVND
                     VKEDEQILDIGDASAQQLAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            complement(2552..3598)
                     /gene="epd"
                     /locus_tag="OPY25_004117"
     CDS             complement(2552..3598)
                     /gene="epd"
                     /locus_tag="OPY25_004117"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HCS0929579.1"
                     /translation="MTVRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRHEREQLFVGDDVIRILHERTLADLPWRELGVDVVLDCTGV
                     YGNREHGEAHIAAGAKKVLFSHPGSNDLDATVVFGVNQNQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLAAG
                     ITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKASEVNQLLQKAAQGAFHGIV
                     DYTESPLVSIDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     AVGFRLDASASTKL"
     gene            3972..4397
                     /locus_tag="OPY25_004118"
     CDS             3972..4397
                     /locus_tag="OPY25_004118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCS0929580.1"
                     /translation="MTVSHHNASTARFYALRLLPGQEVFSQLHAFVQQNQLHAAWIAG
                     CTGSLTDVALRYAGQEATTSLTGTFEVISLNGTLELTGEHLHLAVSDPYGAMLGGHMM
                     PGCTVRTTLELVIGELPALTFSRQPCAISGYDELHISSR"
     gene            4423..5001
                     /locus_tag="OPY25_004119"
     CDS             4423..5001
                     /locus_tag="OPY25_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCS0929581.1"
                     /translation="MARRPFSSQSLVLIVIAIAINMIGGQLISMLKLPIFLDSIGTLI
                     SAVLLGPFIGMLTGLLTNLLWGLLTDPIAAAFAPVAMVIGLVAGWLARAGWFRTLPKV
                     IVSGVVITLAVTLVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
                     VDKILTAIIVWVLLRQLPLRTTRHFPAMSAVR"
     gene            5002..5709
                     /locus_tag="OPY25_004120"
     CDS             5002..5709
                     /locus_tag="OPY25_004120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCS0929582.1"
                     /translation="MHPFTSLTLWALAACTTLLLPAQTVFPVYSAAAFLCLLALKSTR
                     RRAKYVAWLMLSLGFGLWLVHGGWLTEWISGQPRDPQRWVYAVTLWLRLLAIVSTSQL
                     WMQYVPVQRFIRALFASRLPPGIAYLFAGPLLVVEQLKRQLTIVHEAQRARGVPLDEG
                     WYQRLRAMPALIVPLTQNALNDLTIRGAALDMRGFRLHRARTTLWAPKDSMLQRVARY
                     GMVLLILAEAGVWIWLR"
     gene            5697..6374
                     /locus_tag="OPY25_004121"
     CDS             5697..6374
                     /locus_tag="OPY25_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCS0929583.1"
                     /translation="MVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTL
                     AQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVEQSPTIHLVQQSPYLQLSGCTFSVE
                     EEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQ
                     PRLLVLDEAFSRLTSAATGTLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRN
                     GALTPLC"
     gene            6368..>7017
                     /locus_tag="OPY25_004122"
     CDS             6368..>7017
                     /locus_tag="OPY25_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCS0929584.1"
                     /translation="MLTLNQVAYRWPDAAADCLHAISLELRDGEWLALTGDNGAGKST
                     LLRIMAGLLSPTSGSVTLNGEPIAQLKNRQRAAAIGVLFQEAENQIFHSNVAQEVAFG
                     LKLQRLSAEDISRRTQAALRLCQLTDVAEAPPLDLHAAQRRMVAVASLEAMAPPVLLL
                     DEPSRDFDAHWLTVFEHWLATCRARGTSVVAISHDAAFTRRHFSRVVRLENGRLSKG"
BASE COUNT         1491 a         1920 c         1907 g         1699 t
ORIGIN      
        1 accccctttt gatttcttgt tgaacttttg cagttgccag accgcaagat gttttaacaa
       61 atcaaaaggg gttttaataa ctggcttaaa gctgaaagct ttccggaacc cccagcctag
      121 ctgggggttt tccatagaca aaaaaatggc ttcccgaggg aagccatttc aatcagcaga
      181 ctatattaca gaacgtcaat cgcgttcagt tctttaaatg ctttttccag acgagcgatc
      241 atcgaagtct ggccagcacg cagccatacg cgcgggtcat agtatttctt gttcggctga
      301 tcttcgcctt tcgggttgcc cagctgacct tgcagatacg cttcgttttc tttgtagtaa
      361 ttcagaacac cttcccaggt tgcccattgg gtatcggtat cgatgttcat tttcactacg
      421 ccgtagctta cggagtcttt gatttcctga gcagtagaac cggaaccgcc gtggaaaacg
      481 aagttcaggc tgttgtgcgg caggttgtgt ttcttagaaa catagtcctg agaatcacgc
      541 aggatggtcg gggtcagaac cacgttaccc ggcttgtaaa cgccgtgtac gttaccgaag
      601 gaagcggcaa tggtgaaacg cgggctgatt ttgctcagct cagtgtacgc gtaatcaaca
      661 tcttccggct gggtgtacag agcagaagcg tccatgtggc tgttgtccac gccgtcttct
      721 tcgccaccgg tgcaacccag ttcgatttcc agagtcatgc caattttgga catgcgcgcc
      781 aggtatttgg agcagatttc gatgttttcg tgcagagact cttcagacag gtcaatcatg
      841 tgagaagaga acagcggttt accggtagcc gcgaagtgtt tttcacccgc gtccagcaga
      901 ccgtcgatcc acggcagcag tttcttcgcg cagtggtcag tgtgcaggat aaccggcacg
      961 ccgtagtgtt cagccatctg gtgaacgtga tgcgcgccag agatagcgcc caggattgcc
     1021 gcgccctgag gtacgtcagt tttcacgcct ttacccgcga tgaaggacgc gccgccgttg
     1081 gaaaactgaa cgatgaccgg tgctttaact tttgcagcgg tttccagaac agcgttgatg
     1141 gaatcagtgc ccacgcagtt aactgccggc agagcaaaat tgttttcttt tgctacctgg
     1201 aacactttct gtacgtcatc accagtgatc acgcctggtt ttacgaaatc aaaaatttta
     1261 gacatgtttc gttgtcctgt atcgtcgggc tttgggaaaa aacacgggcc gccctgaatg
     1321 tcagatcggc gataaatcaa cgggcaggaa tccctgcccg taacgattac ttcttagcgc
     1381 gctcttcgag catcgctacg gctggcagaa ctttaccttc cacgaattcg aggaatgcgc
     1441 cgccgccagt agaaatgtag gaaattttgt cagcaatgcc gaacaggtcg attgccgcca
     1501 gggtgtcgcc gccgccagcg atggaaaacg cttcgctatc agcgatggca ttcgccacga
     1561 tttcagtccc tttacggaag ttcgggaact caaacacgcc aaccgggccg ttccacagaa
     1621 tggttttggc attcttgagg atttcagcca gctgctgagc ggaagcatcg ccgatatcca
     1681 ggatctgctc gtcttctttc acgtcgttaa cggatttcag agtcgctggt gcggtttcgg
     1741 agaactcggt ggcaacgcga acatcggtcg gaaccgggat atcgcaagtg gtcagcagac
     1801 gttttgcttc gtcaaccagg tcagcttcgt acagggattt accgacgctg tggccctgag
     1861 cggcaacgaa ggtgttggcg ataccgccgc cgacaatcag ctggtcagcg attttagaca
     1921 gggaatccag aacagtcagt ttggtagata ctttagaacc accaacgata gccaccatcg
     1981 gacgagccgg ctctttcagc gctttaccca gtgcatccag ttcagcggcc agcagcgggc
     2041 ctgcgcacgc gacgtcagca aatttgccga taccgtgggt agaagcctgc gcgcggtgcg
     2101 cagtaccaaa ggcgtccatc acaaatacgt cacacagggc ggcatatttt ttagacagcg
     2161 cttcgtcgtc tttcttttcg cctttgttaa agcgaacgtt ttccagaacc accagctcac
     2221 cttcggccac gtcaacgccg tccaggtaat ctttgaccag gcgaaccggg ttagacagtt
     2281 tgtctttcag gtagttaaca accggcagca gagagaattc ttcgttgtac tcgccttcgg
     2341 taggacgacc caggtgggaa gttaccatca ctttcgcgcc ctgtttcaga gccagttcga
     2401 tggtcggcag agaagcgcgg atacgcgcgt cgctggtcac tttcccttct ttaacaggta
     2461 cgttcagatc cgcacggata aaaacgcgtt tcccggccag atccagatcg gtcatcttaa
     2521 ttacagacat ggtgaatcct ctcaatgatg cttaaagttt tgtcgacgct gacgcgtcga
     2581 gcctgaaacc aactgcggcc atcgctaacg tggtgtcgag catcctgtta gcaaagcccc
     2641 attcattatc gcaccagacc agcgtcttga tcaggtgggc gccactgacc cgggtttgcg
     2701 tgccatcaac aatggcgctg tgcgggtcgt ggttaaaatc tatcgagacc aacggtgatt
     2761 ccgtatagtc aactatacca tgaaatgcac cttgtgctgc tttttgcagc aactggttga
     2821 cttcactagc ttttactggt tttttcaccg ttacgcttaa atcgatcgcc gtcacattaa
     2881 tggttggaac gcgcaccgca atcgcctcaa aacggtcgtt aaactgcggg aatatacgcg
     2941 taatgcctgc cgccagtttt gtatctaccg ggataatcga ctggctggcc gcgcgcgtgc
     3001 gccgtagatc ggagtgatac gcgtcgatca cctgctgatc gttcatcgcg gagtggatcg
     3061 tcgtgacggt accagactcg atgccgtaag catcatccaa caatttaatg acgggaatta
     3121 tgcaattcgt ggtacaggac gcgtttgaga caatacgatg ttccgcacgc agttggttct
     3181 ggttcacgcc aaaaacgacg gtggcgtcaa gatcgttgct gcccggatga gaaaagagca
     3241 ctttcttcgc gccagcggca atatgcgcct cgccatgctc ccggttgcca tatacgcccg
     3301 tacaatccaa cacgacatcc acgcccagtt cgcgccacgg cagatccgcc agcgttcgtt
     3361 catgcagaat acgaatgaca tcgtcgccga caaaaagctg ctcgcgctcg tggcgaacct
     3421 cccatgcaaa acgcccgtgg ctggtatcgt atttcaacaa atgcgccatg cctgcggcat
     3481 ccgccagctc gttgatggcc accacggtaa tttccgcccg acgtccggat tcatacaaag
     3541 cacgaaccac gttacgcccg atgcgaccaa agccattaat cgctatgcgt acggtcatag
     3601 gtctcctgca aggctatccc gattcagatg aggctgacag agtaatgcag cttatcgtcg
     3661 agtaaaacct cacctgtcgc aaactgcgac tgattggtta attgtcgaac atttaattaa
     3721 ctgaaacgct tcagctagaa taagcgaaac ggggaataaa aggaatgttt gtccagtcga
     3781 agaagacagt tatctgacct gcatcacatt tcatggccgc ttacgctgca atttattcca
     3841 tatttaagaa tcaccagtac atccgtcaga tcttttcatc gtcgcgtcac aaatactgat
     3901 ttatatcaga aagcgctgtc gccagcgtct atattatcag cgccacgtcc gagtctcgga
     3961 gtcctgtaac gatgactgta tctcaccaca atgcctctac agcgcgcttt tacgcgcttc
     4021 gtctgcttcc cggccaggaa gtgttttccc aattacacgc ctttgtgcaa cagaaccaat
     4081 tacatgccgc ctggattgca gggtgtaccg gcagtctgac cgacgttgcg ctgcgttatg
     4141 ccgggcaaga agcgaccaca tcgctcaccg gcacgtttga agttatctcg ctaaacggca
     4201 cgcttgaatt gaccggcgag catctgcatc tcgcggtatc ggatccctac ggggccatgc
     4261 tcggcggcca tatgatgcca gggtgtaccg tgcgtaccac gctggagctg gttatcggcg
     4321 agctgccagc gctgacgttc agccgtcaac cgtgcgccat ttccggttat gacgaactgc
     4381 atatttcttc ccgttaattg acgactcttt aagaggtact ttatggcgcg tcgcccgttt
     4441 tccagccagt ctctggtgct gattgtcatc gctattgcca tcaatatgat tggcggacag
     4501 cttattagca tgttgaagct gcctattttt ctcgactcga tcggcacctt aattagcgcg
     4561 gtactgttag ggccgttcat cggcatgttg actgggcttc tgaccaactt gctgtggggg
     4621 ctgcttaccg accctatcgc tgccgcgttt gccccggtag cgatggttat cggtctggtc
     4681 gccgggtggc tggcgcgcgc aggctggttt cgtaccctgc ccaaagtgat cgtcagcggg
     4741 gtcgtcatta cgttggcggt gacgctggtc gccgtaccgc ttcgtaccgc gctttttggc
     4801 ggcgttaccg gtagcggcgc tgatttgttc gtcgcctgga tgcattcaat gggccaaaac
     4861 ctggtggagt cagtcgcgat taccgtcata ggcgctaatc tggtcgataa aattctgacg
     4921 gcgatcatcg tttgggtgct gctgcgtcag ctaccgttac gtacgacacg gcattttcct
     4981 gcgatgtcag ccgtacgcta aatgcatccg tttacctcgt taaccttatg ggcgttggcg
     5041 gcctgcacca cgctgctact ccctgcgcag accgtgttcc cggtttatag cgcggcggcc
     5101 ttcctctgtc tgctggcgct gaaatcaacg cggcggcggg cgaagtatgt cgcctggctg
     5161 atgctgtctt tagggtttgg gctatggctg gtacatggcg gttggctaac ggaatggata
     5221 agcgggcagc ctcgcgatcc gcagcgctgg gtatatgccg ttacgctatg gctacgtctg
     5281 ctggcgatcg tgtcgacgtc gcagctatgg atgcagtatg tgccggttca gcggtttatt
     5341 cgcgccctgt tcgcttcacg tctgccaccc ggcatcgctt acctgttcgc tggcccgctg
     5401 ctggtcgtcg aacagctcaa acgacaactg acgatcgttc atgaagccca gcgcgcgcgc
     5461 ggcgtaccgc tggatgaagg ctggtatcag cggctacggg caatgcctgc gctgatcgtg
     5521 ccgcttacgc aaaatgcgct taacgatctg acaatacgcg gcgcggcgtt ggatatgcgg
     5581 gggtttcggc tgcatcgagc ccgaaccacg ctgtgggcgc cgaaagatag catgttacaa
     5641 cgggttgcgc ggtatggcat ggtactgcta atactggcgg aagcgggagt atggatatgg
     5701 ttacgttaga gcagtttcgt tatcttccgt ccgatgcgac acgcccgccg gcatgttttg
     5761 atttccacta ttcaacaccc ggaatagtgg cgatagtcgg cgataacggc agcggaaaaa
     5821 gtacgctggc gcaactgatg gctggctggt atccggatta tctccccggc gatattgacg
     5881 gcacaggcct actgcttggc gtacctatcg ggcggctccc gctggtagaa cagtcgccca
     5941 ccatccacct ggtgcagcaa tcgccttatt tacagctttc cggctgtacc tttagcgtag
     6001 aggaagaggt ggcgtttggc ccggagaatc tcggcctcca tgaagcggaa attctacggc
     6061 gcattgacga ggcgctgact ctgacaaact gccagtcgtt acgccatcgc catcccggca
     6121 cgctctccgg cggcgaaacg cagcgggtag tgattgccag cgcgcttgcc atgcagccca
     6181 gattattagt tcttgatgaa gccttcagtc ggctgacgtc agcggccacc gggacactgc
     6241 tggaacggtt acaacagtgg gcgctggaac gtcattctct cattgtgctt tttgagcgta
     6301 atcatttccc ctttctgacg cgatgccagc gggtatggca attgcgcaac ggagcgctaa
     6361 ccccattatg ttgacgttaa atcaggtcgc ttatcgctgg ccagatgccg cagccgactg
     6421 tctgcacgcc atctcgcttg aacttcgtga cggcgaatgg ctggcgttga ccggcgataa
     6481 cggcgcggga aaatcaacgc tgttacggat tatggccggc ctgctttccc ccacttccgg
     6541 ctcggtaacg cttaatggag agccgattgc gcagcttaaa aatcgtcaac gcgccgccgc
     6601 tatcggcgta ctctttcagg aagcggaaaa ccagattttc cacagcaatg tcgcacaaga
     6661 ggtcgctttt gggctgaaac tacagcgctt atcggcggag gatatttcac ggcgcacgca
     6721 ggccgcgctg cggttatgcc agctaacgga cgtcgccgag gcgcccccgc ttgatctgca
     6781 cgccgcgcag cgccggatgg tggcggtcgc cagtctggag gcgatggcgc cgccggtgtt
     6841 attgctggat gaacccagcc gggattttga cgcccactgg ctaaccgtat ttgaacactg
     6901 gctggcgaca tgccgggcac ggggaaccag cgtcgtggcg attagccatg acgctgcgtt
     6961 tacccggcgt catttttccc gggtggtacg gctggaaaac ggcaggttgt caaaggg
//
LOCUS       DAJVKX010000177         6954 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.177, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000177 DAJVKX010000000
VERSION     DAJVKX010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6954
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.177"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            227..589
                     /gene="queD"
                     /locus_tag="OPY25_004123"
     CDS             227..589
                     /gene="queD"
                     /locus_tag="OPY25_004123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HCS0929585.1"
                     /translation="MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCVYRGE"
     gene            complement(679..1476)
                     /locus_tag="OPY25_004124"
     CDS             complement(679..1476)
                     /locus_tag="OPY25_004124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCS0929586.1"
                     /translation="MALRIRVLLENHKGAGTDKSLKARPGLSLLVEDESTSILFDTGP
                     DGSFMQNASAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPNIARERYAAIT
                     FLGITRKIKKLSCEVDYSRYRMMYTCGPLPIGENFIWSGEIPVVAPEAYGIFGGHDAE
                     PDSILDEGVLIYQSTKGLVIIMGCGHRGIANIVRHCQNITGIKRIYALIGGFHLRCAS
                     PFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF"
     gene            complement(1960..2631)
                     /gene="queE"
                     /locus_tag="OPY25_004125"
     CDS             complement(1960..2631)
                     /gene="queE"
                     /locus_tag="OPY25_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HCS0929587.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     DKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLM
                     PLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKH
                     PVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
     gene            complement(2767..4065)
                     /gene="eno"
                     /locus_tag="OPY25_004126"
     CDS             complement(2767..4065)
                     /gene="eno"
                     /locus_tag="OPY25_004126"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCS0929588.1"
                     /translation="MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTEN
                     KSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(4148..5785)
                     /gene="pyrG"
                     /locus_tag="OPY25_004127"
     CDS             complement(4148..5785)
                     /gene="pyrG"
                     /locus_tag="OPY25_004127"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HCS0929589.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQL
                     AVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVE
                     TRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARN
                     VAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSD
                     DSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK"
     gene            complement(6013..6813)
                     /gene="mazG"
                     /locus_tag="OPY25_004128"
     CDS             complement(6013..6813)
                     /gene="mazG"
                     /locus_tag="OPY25_004128"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HCS0929590.1"
                     /translation="MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETY
                     EVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHV
                     FGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGF
                     DWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAEIA
                     LQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL"
BASE COUNT         1709 a         1832 c         1632 g         1781 t
ORIGIN      
        1 aacaattaaa gaagggttgg aaataacaaa taaccaaatg aactaacctg ttttagttat
       61 cgttattaac gccaaaatcg atttcataat tgattgataa ttattaaatt ttctggaaat
      121 tcttaaatta attgcccgtt acaaggcgga gaatggtttt agttaatgat aaaaaatgcg
      181 ctttccggta ccctacagcg gtttttttat tgcctgagag ttcatcatgt ccaccacgtt
      241 gtataaagat ttcacctttg aagccgctca ccgcctgcct cacgtgcctg aagggcataa
      301 gtgcggccgc ctgcacggac actcatttat ggtgcgtctc gagattaccg gtgaagtcga
      361 tccgcatacc ggttggatta tggatttcgc ggatctcaaa gcggcgttta aacctactta
      421 cgatcgtctt gatcactact atctgaatga tattccagga ctgtccaatc ccaccagcga
      481 agtgctggca aaatggattt gggatcaggt taagcccgtc gtgccgctac tgagcgccgt
      541 gatggtgaaa gagacctgta cagccggctg cgtctatcgc ggcgaataag gtttattaac
      601 gcgtgggctg gatggtaaat tgattccagc ctatccacac gacgttttat cagtgaaaac
      661 attgcccagc gcgcggtgtt aaaagcgcag cacatcaccg gttgcaggtg cggttatttc
      721 cggtagccac aaccgccccc aggccccggt acagtgacaa ccgcatagtt tttcaggttt
      781 ttgttcttgc agaaagcgcc tgactcgcca cagcgtgaac ggtgatgcgc agcggagatg
      841 aaatccgccg ataagcgcgt aaatccgctt tataccggta atgttctgac agtgccggac
      901 aatatttgcg atcccccgat gcccgcatcc cataatgatg actaatcctt ttgtcgattg
      961 gtaaatcagt acgccctcat ccaaaataga gtccggctcc gcatcgtggc cgccaaaaat
     1021 gccgtaggct tcaggcgcga ccaccggtat ttcccctgac cagataaagt tttcgccaat
     1081 cggcaggggg ccacacgtgt acatcattcg gtagcgtgaa tagtccacct cacacgacaa
     1141 tttttttatt ttccgggtaa taccgagaaa agttattgcc gcataacgtt cgcgcgcaat
     1201 attgggatgg cagatgattc gactgttatc aggaagccac ggcacgccgc cgcaatgatc
     1261 gtaatgacca tgcgaaagca ccacagcaga cacatcggac aggtcgatcc ccatcgccga
     1321 cgcgttttgc ataaaactgc catcagggcc ggtatcgaac aagatcgacg tagactcatc
     1381 ctcgaccaac aggcttaatc ctggccgggc cttcaacgat ttatccgttc cagctccctt
     1441 atgattttcg agcaataccc tgatccttaa cgccatggcc ttctcctgta taaaagcctc
     1501 cccgggaaaa cgcggccttt ttactttaca ggtttgtagc agccattact ggtacacaga
     1561 ttatgattat gcaacggcta tccttgttga cgtggggaat actgctacac gcaaaaattc
     1621 cagtcgttgg cgcacggttt atccccgctg gcgcggggaa cacactaaac gtatatcatt
     1681 gtttataaac tactttttat tagcaccaca ttctaccaac ataatagcaa caatttaaat
     1741 tattaaagaa cagctaattt gctgattttg atgcaaaaaa gttcatagaa tgattttttc
     1801 tttaaattta ccaaaataac gtgatccgtg catcgctatg gaaaaattta tcagcgcttt
     1861 tatacactca tcgaaattca catagagaaa ataaacaatg caaggtaatg gatgagtcac
     1921 agacggcaac ggcaggccgt ccgtaagatt aataatgcct caggcgatat ttaaatattt
     1981 atgcgtttgc atagacagcc gccagttacg cgcaatacac gtttcaatac acagacgcgt
     2041 cgcgtcttct ttctggctaa tgggctgcaa agcaatcacg cgcggtttat catcgctcaa
     2101 cgtggctaac agttcatcca gcgcctcaat atcacgaact cgcccaacgg gatgcttgat
     2161 ttcattggcg cgctccagcg cctgggaaag cacgtcatat cccccgcgca tattcacttt
     2221 tggtgaaacc gtgacccagg tattgggcgt acagcgcact tcgtgcgtcc cgctggtttc
     2281 aatctggcaa ctaaaaccac tcttttcaag cagatcggtg agcggcatga ggtcgtgaat
     2341 acagggttcg ccaccggtga tgacaacgtg acgcgcggta tagccctgac gattaattac
     2401 tgccagcaag tcttcactgc tcgcagcacc ccatttgtcg ctctctttgg tttttgccag
     2461 aatgctgaac agagacactt cccgatcgct cagtttatcc caggtatgct tagtatcaca
     2521 ccaggcacag ccgaccggac atccctgtaa acgaataaaa atagcgggga cgccggtaaa
     2581 ataaccctcg ccttgtaggg tctggaacat ctcgttaatc gggtactgca tagcgttctc
     2641 tgttaagggg ataatcgtta attattgcag atttcgtctg cccggtcatg cacagcggct
     2701 gcgctattga acagatacaa aaaaacccgc cgaagcgggt ttatacgtta agaggtaaaa
     2761 gcaggattac gcctggcctt tgatctcttt acgaccgttg tacggtgctt tttcgcccag
     2821 agcttcttcg atacgaatca gctggttgta tttagcaaca cggtcagaac ggctcataga
     2881 accggttttg atctggcctg cagcggtacc aacagccagg tcagcaatgg tagcgtcttc
     2941 agtttcacca gaacggtgag agatgacagc agtgtagcca gcgtctttcg ccatcttgat
     3001 tgcagccaga gtttcggtca gagaaccgat ctggttgaat ttgatcagga tggagttagc
     3061 gatgcctttc tcgatgcctt ctttcaggat tttggtgttg gttacgaaca ggtcgtcacc
     3121 aaccagctgg attttgtcgc ccagtacttt ggtctggtat gcaaaaccgt cccagtcaga
     3181 ctcgtccaga ccatcttcga tggaaacgat cgggtactgt ttggtcagtt cttccaggaa
     3241 gtgggtgaat tcttcggagg tgaatgcttt gttgccttcg ccagccagaa cgtatttacc
     3301 gtctttgtag aattcagatg ctgcgcagtc catcgccagg gtgatgtctt tacccagctc
     3361 gtaaccagcc gctttaaccg cttcagcgat aacagccagc gcttcagcgt tggaacccag
     3421 gttcggcgca tagccgcctt cgtcacccac agcggtgttc atgcctttgc ctttcagcac
     3481 ttttgccagg tgatggaaaa cttcagaacc catacggatg gcttctttaa ccgttttcgc
     3541 gccaaccggc tggatcatga attcctggat gtcgacgttg ttgtcagcgt gctcgccgcc
     3601 gttgatgatg ttcatcatcg gaaccggcat ggagtatttg cccggcgtgc cgttcagttc
     3661 agcaatgtgc tcgtacagcg gcataccttt agcggcggca gcagctttgg cgttagccag
     3721 agagacagcc agaatggcgt ttgcaccgaa gttagatttg ttttcagtac cgtccaggtc
     3781 gatcatgatt ttgtcgatgc cagcctggtc tttagcgtct ttgccaagaa tagcctgagc
     3841 gatcgggccg ttaaccgcgc caacagcttt ggttacgcct ttacccagga aacgggattt
     3901 gtcgccatcg cgcagttcca gcgcttcgcg ggaaccagta gaagcacctg acggagccgc
     3961 cgccatacct acgaaaccac cttccaggtg tacttcagct tcaacagtcg ggttaccacg
     4021 ggagtcgatg atttcacgac cgatgacttt aacgattttg gacattaggt tttcctcaag
     4081 tcactagtta aactaaaact tcagacaaac ggtgcaccgc tgagggtgca ccgccgttct
     4141 aactttttta cttcgcctga cgtttctgat gctcgttggc ggctttaaca aagccggcga
     4201 acaacggatg tccatcacgc ggcgtggaag taaattccgg atggaactga caggccacga
     4261 accacggatg attcggtacc tcaatgatct cgactaactg atcatcaccg gaacggcctg
     4321 cgacacgcag acccgctgct tcaatttgtt tcaacaacat attgttgact tcgtaacgat
     4381 ggcgatgacg ttcaacaatc gtcgacgcgc cgtacaactg acgtaccagg ctgtcatcgc
     4441 taagctggca ctgctgcgcg cccaggcgca tggtgccgcc cagatcgctt ttctcgctac
     4501 ggacttcaac gttaccgtct tcatcgcgcc actcggtaat taacgccaca accgggtact
     4561 tacagtctgg cacaaattcc gttgagttgg cgttgtccat gccggccacg ttacgagcga
     4621 actcaatcaa cgcaacctgc atccccaggc aaatgcccag ataaggaata ttgttttcac
     4681 gcgcatagcg cgcagtggcg attttacctt caacgccacg atagccgaag ccgccgggga
     4741 tcaggatagc gtccaaatct ttcagaattt cgacgccgcg cgtttcaaca tcttgcgaat
     4801 cgatcaattt gatgttgacg gtaacgcggt ttttcagacc accgtgtttc agcgcttcga
     4861 tcaccgactt ataggcatcc ggcagttcaa tatatttgcc gaccatgccg atagtcactt
     4921 cgcctgccgg gttcgcttct tcgtaaatga cctgttccca ttcagacagg ttagcttccg
     4981 gacagttcaa gctgaatcgt ttacaaatat aatcatcaag cccctgagat ttcaacaggc
     5041 ctggaatttt ataaatggaa tcgacatctt tcattgaaat aacggctttt tccggcacat
     5101 tacagaacaa tgcaattttt gcacgctcgt tggcaggaac cgcacggtcg gaacgacaaa
     5161 tcagaatatc gggctgaata ccgatagaca gcagctcttt cacggagtgc tgagtcggtt
     5221 tagttttcac ttcgcccgca gccgccaggt aaggtaccag cgtcaggtgc ataaacagcg
     5281 cgtgttcacg accgatatct accgccaatt gacgaatcgc ctcaagaaac ggcagcgatt
     5341 cgatatcacc gacggtaccg ccgatttcca ccagcaccac atcgtggcct tcgccacctt
     5401 ccagcacgcg ctctttaatc gcgttagtga tgtgagggat gacctgtacg gttgcgccca
     5461 gatagtcgcc acggcgttct ttacgcagaa cgtcggagta gatacggcca gtcgtgaagt
     5521 tgttgcggcg agacatcttg gtgcggatga aacgctcgta gtgccccagg tccaggtcgg
     5581 tttcagcgcc gtcttcagta acgaacactt ccccgtgttg gattgggctc atagtacccg
     5641 gatcgacgtt gatgtacgga tccagtttca tgatggtcac gttgagacca cgggcttcca
     5701 gaatggctgc gagggaggct gcggcaatgc ctttacccag agaggatacg accccgccgg
     5761 tcacaaaaat atagttcgtt gtcatgcgga acctgagaag ttaggtttaa aagacgatgg
     5821 aataaccagg acgggaaagc agtatacccg aacatgacct acgccacaaa ctttcattat
     5881 tcctcctctt cgccaggctg acattcacac agggagggag aaaatagccc ctttgaggta
     5941 aatgtttttg acgtaaatca agcgcttgtt atttaaaaaa tcacacaaat cgctcttgac
     6001 cgcctaaaac ctttagagat caatttcctg gcgttttact tcctgccaaa cttcttccat
     6061 tgtttccagg tctaccccgg tcatttccag gcctctggct gcgacaatac gttcaacttc
     6121 gcgaaaacga cgttcaaatt tatcgttcgc tttttgcaaa gcgatctccg ctttcgtacc
     6181 taaatgacgc gccatgttga ccgtggcaaa gagcaaatcg cccatttcct cttccagttt
     6241 agcctgatca acaaccgcct gccgcgcctc gaacatcacc tcatcgatct cttcatagac
     6301 cttatcgacg accggcccca gcgtcgtcca gtcgaagccc acgtttgaac accgtttctg
     6361 gattttttgc gcgcgcatta aggccggtaa gctgcgcgga atatcgtcca gcgcggaatg
     6421 ctgcgctttt tgcgcgcgct cttccgtttt gatttgctcc cagcgaacta atgcttcttc
     6481 gctattatcc gcggaaagct cgccaaaaac atgcggatgg cggcgctcca gcttgtcgct
     6541 gatggcagcg caaatatcat taaaatcgaa gcggccttct tcctgcgcca tctgcgcgta
     6601 aaacaccacc tggaacaaca ggtcgcccag ttcgccgcgc aaatcgtcaa aatcctcacg
     6661 cgcaatcgca tccagtactt cataggtttc ttccagtgta taaggcgcga tgctggcgaa
     6721 ggtctgctct ttatcccacg ggcagccgtt ttccgggtcg cgcaggcgct gcatgagggt
     6781 gagaagacgg tcaatttgat ggttagttgt catggtcttt aatcggttgt aaatactagc
     6841 gacaattgta acgtattatt cttaaccatt cacgcacaga gacactacga caacgcctat
     6901 ataataaaat atattgttaa caggtgttga atgctacctt tcccgtataa cttt
//
LOCUS       DAJVKX010000178         6863 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.178, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000178 DAJVKX010000000
VERSION     DAJVKX010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6863
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.178"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..981
                     /gene="tehA"
                     /locus_tag="OPY25_004129"
     CDS             <1..981
                     /gene="tehA"
                     /locus_tag="OPY25_004129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HCS0929591.1"
                     /translation="NLPAGYFGIVLGTIGMGFAWRYASQIWAISHWPGDIMEILAMII
                     WALLTLAFLSRLVRFPHSVMAEVRHPVMSSFVSLFPATTMLVAIGFVPWYRPLAVALF
                     SVGVVIQLAYAAWQTAGLWRGAHPEEATTPGLYLPTVANNFISAMACGALGYNDAGLV
                     FLGAGVFSWLSLEPVILQRLRSCGELPAVLRMSLGIQLAPALVACSAWLSVNGGEGDT
                     LAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALTTTGLHLGHGSESGFF
                     HILAVPLFIFTNAIIALLLVRTFLLLVQGTLLIRTERAALLKTEEKNDRS"
     gene            968..1564
                     /gene="tehB"
                     /locus_tag="OPY25_004130"
     CDS             968..1564
                     /gene="tehB"
                     /locus_tag="OPY25_004130"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HCS0929592.1"
                     /translation="MTVRDENYFTEKYGLTRTHSDVLAAAKVVAPGRTLDLGCGNGRN
                     SLYLAANGYDVTAWDKNPASMANLERIKAAEGLDNLQTDLVDLNTLTFDGEYDFILST
                     VVMMFLEAQTIPGLIANMQRCTKPGGYNLIVAAMDTPGFPCTVGFPFAFKEGELRRYY
                     EGWDMLKYNEDVGELHRTDENGNRIKLRFATMLARKTA"
     gene            1720..2388
                     /locus_tag="OPY25_004131"
     CDS             1720..2388
                     /locus_tag="OPY25_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HCS0929593.1"
                     /translation="MRTHTLFKVAVLTGLLALSGCASKVTQPDKYSGFLKNYSDLKET
                     TSATGKPVLRWVDPHFNDSNYDSIVYNPITYYPIPKPTTQVGQQVLDKLLAYTNTKVK
                     SAIEQRKPLVTTAGPRSLIFREAITGVDTSKEGLQFYEVIPVALIVAGTQMATGHRTM
                     DTHLYFEGELIDAATNKPVVKVVRQGEGKDLSNSSTPMAFETLKQVVDDMATDTSMFD
                     TNKK"
     gene            complement(2442..3620)
                     /locus_tag="OPY25_004132"
     CDS             complement(2442..3620)
                     /locus_tag="OPY25_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HCS0929594.1"
                     /translation="MRLLSLPLPTVLSGLVAVLVGYASSAAIIWQAALAAGATPAEIA
                     GWMTALGIAMGISTLTLTLWYRAPVLTAWSTPGAALLVTGLQGLSLPDAVGIFIVANA
                     LIVLCGVTGLFARLMRIIPHSLAAAMLAGILLRFGLQAFGTLNGEFVMCGGMLLAWLL
                     FKVFAPRYAVIAAMVMGITVALIQGKMAMSGIHFAPVWPTFVPPHFSFAQSLSVAVPL
                     FLVTMASQNAPGVATMKASGYQLPVSPLMIFTGLLALLLSPFGVYSICIAAITAAICQ
                     SPDAHPDPTRRWLAAAAAGVFYLLAGWFGGSITELMVALPVSWVQMLAGLALLSTISG
                     SLYQALTHESERDAAVIAFLVTASGLTLMGIGSAFWGLIAGGIGYAILTRTRRPSLSG
                     "
     gene            3712..4248
                     /locus_tag="OPY25_004133"
     CDS             3712..4248
                     /locus_tag="OPY25_004133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929595.1"
                     /translation="MDNLTHYLATTLRTLRHQRGWSLSRLAEISGVSKAMLGQIERNE
                     SSPTVATLWKIATGLKVPFSMFISPPQAEFPPTFDPQQQAMVITPLFPWDPELCFDYF
                     SLLLAPGAVSESTPHKAGVIEHVVVIQGRLDMCTGGVWQTIDAGKGLRFAGDTAHTYR
                     NSSDQTVHFHSLIHYPRD"
     gene            4327..6291
                     /locus_tag="OPY25_004134"
     CDS             4327..6291
                     /locus_tag="OPY25_004134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCS0929596.1"
                     /translation="MRQQPHYLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLRDIADLVPFAHRYGARIFVTLNTILHDDELEPAQRLITDLYNTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRSVEKAKFLADVGFSQIVLARELNLSQIAAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEQRGDLARAS
                     VGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVLNVAKDYLDV
                     EATEPLANGDGLNVLIKREVVGFRANTVEKTGHNRYRVWPNDMPADLHKVRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIMLGGWQEQLILTLTSEDSVCITHTLDGVFEEANNS
                     EKALNNLTAGLAKLGQTLYYARDMQVTLPAALFVPNSLLNQFRREAIDMLDAARLAHY
                     QRGRRKPVAQPAPVYPQTHLSFLANVYNHKAREFYHRYGVQLIDAAYEAHQEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVHGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPQPGSVVASVSPEALMKTLLKRRGV"
     gene            complement(6292..6522)
                     /locus_tag="OPY25_004135"
     CDS             complement(6292..6522)
                     /locus_tag="OPY25_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2554 family protein"
                     /protein_id="HCS0929597.1"
                     /translation="MLTKTLSVVLLTCALFSGQLLAKQQDHAFVWFATGGHQLRHEAD
                     SDELRAAAEESAEGLREHHNWQKSRKPESYFR"
     gene            complement(6796..>6863)
                     /locus_tag="OPY25_004136"
     CDS             complement(6796..>6863)
                     /locus_tag="OPY25_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="secreted effector protein SifB"
                     /protein_id="HCS0929598.1"
                     /translation="LFSEDLSSLVETTKNEAHYQS"
BASE COUNT         1638 a         1713 c         1856 g         1656 t
ORIGIN      
        1 aatctgcctg cgggctattt tggcatcgtc cttggcacta tcggtatggg attcgcctgg
       61 cgttatgcca gccagatatg ggcaataagc cactggcccg gcgacatcat ggagatcctg
      121 gcgatgatta tttgggcact cttgaccctg gcgttcctta gccgtctggt gcgctttccc
      181 catagcgtga tggctgaagt gcgacatccg gtaatgagca gttttgtcag cctgtttccc
      241 gccaccacga tgctggtcgc gatcggtttc gttccctggt atcgcccgtt ggccgttgcg
      301 ctattcagcg tgggggtcgt catacaactg gcgtatgccg cctggcagac ggcgggtctt
      361 tggcgcggag cgcatccgga agaagcgaca accccaggac tttatctgcc cacggtagcg
      421 aataatttta tcagcgctat ggcctgtgga gcgctcggtt acaatgatgc cggactggtg
      481 tttttaggcg caggcgtctt ttcgtggtta agtctggaac cggttatttt gcagcgactg
      541 cgtagctgcg gcgaattacc ggcggtgctg cgtatgtcgc tgggtatcca actggcgccc
      601 gcgctggtcg cctgtagcgc ctggctgagc gtcaatggcg gggagggcga cacgctggcg
      661 aaaatgctat tcggctacgg tctgttacag cttttattta tgctgcgatt aatgccctgg
      721 tatttatcac aaccgtttaa tgcttccttc tggagttttt cgttcggcgt ttccgcgctg
      781 acgaccacgg ggttacatct tggtcacggt agtgaatcag ggtttttcca tattctggcc
      841 gtcccgctgt ttattttcac taacgctatt atcgccttat tgctggttcg tacatttcta
      901 ttgctggtgc aggggacgtt gcttattcgc actgagcgcg ctgcactgtt gaaaacggag
      961 gaaaaaaatg accgttcgtg acgaaaatta ctttactgag aaatacggtt taacccgcac
     1021 gcattcggat gtgctggcgg cggcaaaggt tgtcgcgcca ggccgaacgc tggatttggg
     1081 atgtggcaat ggccgtaata gtctgtatct ggccgcgaac ggttatgacg ttaccgcgtg
     1141 ggataaaaat ccggccagta tggctaacct tgagcgtatt aaagcggcag aagggctgga
     1201 taatctgcaa accgaccttg tcgatctgaa tacattgacc tttgacggcg aatacgattt
     1261 tattctctcg acagtggtta tgatgtttct tgaggcgcaa accattcccg gtttaattgc
     1321 caatatgcaa cgctgcacaa aacccggcgg gtataatttg attgttgcgg caatggatac
     1381 gccgggcttt ccctgtacgg tgggattccc gttcgctttt aaagaaggcg aattacgccg
     1441 ctattacgaa ggatgggaca tgctgaaata caacgaagat gtcggcgagc ttcaccgcac
     1501 ggacgaaaac ggcaaccgta tcaaactgcg ctttgctacg atgctggcga gaaaaacggc
     1561 ctgagcgatg caagttctgt aagtcttgct gcgttcggca tttttttgtc gggcgccgcg
     1621 ttcaaattgt gctgtcgtta ccatttttag tgcatccaga atgatttcgt tttgctatta
     1681 tttcctttgc atcattgcga agactaaagg gatcgtttca tgcgtactca tactttattt
     1741 aaagttgcag tgcttactgg cttgctggcg ttatccggct gtgcgtctaa agtcacacag
     1801 ccggataagt attctggatt cttaaaaaat tattcggacc tgaaggagac tacttccgcc
     1861 acggggaaac cggtgttgcg ctgggtagat ccacatttta atgactctaa ctatgacagt
     1921 attgtttaca atccgataac atattacccc atccccaagc caacgaccca ggtcggacag
     1981 caagttcttg ataaactgct ggcttatacg aacactaaag taaaatcagc aattgaacag
     2041 cgcaaaccgc tggtcacgac ggcagggccg cgcagtttga ttttccgcga ggcgattacg
     2101 ggcgtggata ccagcaaaga agggctgcaa ttctatgagg tgatccctgt agcgctgatt
     2161 gtggcgggca cgcaaatggc gacgggccac cggaccatgg atacccacct ctattttgag
     2221 ggtgagctga tagatgccgc gaccaacaag ccggtcgtca aggtagtgcg ccagggcgaa
     2281 ggtaaagacc tgagtaattc cagtacgcca atggcgtttg agacgttgaa acaggttgtg
     2341 gatgatatgg cgacggatac ctctatgttt gacactaaca aaaaataatt ctgcggcgcc
     2401 atcgcaagat ggcgcaaacc ccggcagatt agcggccgcc atcagccaga caacgacggg
     2461 cggcgcgttc tcgttaatat tgcgtagcct atcccgccag cgatcaaccc ccagaatgcc
     2521 gatccgatgc ccatcagcgt tagcccgctg gcggtgacga gaaatgcgat aactgccgcg
     2581 tcacgctcac tttcgtgagt aagcgcctga tacagactac cgctaatcgt acttaacagt
     2641 gccagaccag ccagcatttg cacccagcta accggtaggg cgaccatcag ctcggttatc
     2701 gaaccgccaa accacccggc aagtaaataa aaaacgcctg cggcggcggc cgctaaccag
     2761 cgacgcgttg gatcggggtg cgcgtccggg ctttgacaaa tggcggctgt aatggcggca
     2821 atgcagatag aataaacgcc aaacggcgaa agcagcagcg ccagtaatcc ggtaaaaatc
     2881 attaacggag agacaggaag ctgatagcca gacgccttca ttgtggcgac gccgggggcg
     2941 ttttgcgatg ccatcgtcac caggaagagc ggtaccgcga cgctcaggct ttgagcgaat
     3001 gaaaagtggg ggggaacgaa ggtgggccac accggcgcga aatgaatacc gctcatcgcc
     3061 atcttaccct ggatgagcgc caccgttatt cccatcacca tggcagcaat aacggcatag
     3121 cggggcgcga atactttaaa gagtagccac gccaatagca taccgccgca catgacaaac
     3181 tctccgttga gcgtcccgaa cgcctgcagg ccgaagcgta gcagtattcc cgccagcatt
     3241 gcggcggcaa gagaatgggg gattatccgc atcaaacgcg caaacaatcc cgtgacgccg
     3301 cacagcacaa tcagggcatt ggcgacaatg aatatgccca cggcgtctgg caacgataat
     3361 ccctgaagcc ctgtcaccaa cagagcggcg ccaggcgttg accaggcggt taaaaccggc
     3421 gcacgatacc acaaggttaa cgttagtgtg cttatgccca tggctatacc gagggcggtc
     3481 atccagccgg cgatctctgc gggtgttgcg ccagcggcaa gcgccgcctg ccagataatg
     3541 gcggcggaac ttgcatagcc gaccagaacg gcgaccagac cagataatac agtaggtaac
     3601 ggcagtgata acagacgcat gatcgcctct tgtgcgttat aacggtcagt caatgtagca
     3661 ttgtgcgtta tagcgtacaa gtgatacgct atggccttac aggggggaaa aatggataac
     3721 ctgacacact atctggcgac cacgttaaga acgttacgcc atcagcgagg ctggagttta
     3781 tcacgtctgg cggagatctc cggcgtctca aaagccatgt tggggcagat agagcgtaat
     3841 gaatccagtc cgacagtcgc aacgctgtgg aaaattgcga cgggcctgaa ggttccattc
     3901 tcaatgttta tttcgccgcc gcaggccgaa tttcctccaa ccttcgatcc ccagcagcaa
     3961 gcgatggtaa tcacaccgct gtttccgtgg gaccctgaac tctgttttga ctatttttcc
     4021 ctattgctgg cgcctggcgc ggtcagcgaa tcaacgccgc ataaagccgg cgttatcgaa
     4081 catgtggtgg tgattcaagg tcggctggac atgtgtactg gtggggtatg gcaaaccata
     4141 gacgccggta aaggtttgcg ttttgccggc gatacggcgc atacctatcg caacagtagt
     4201 gaccagacgg ttcattttca ctcgctgatc cattacccac gtgattaagc gggaaaacta
     4261 tttcgttagt ttgcgcttct gactacaata gccgccattt cgctgctatt ggataagaaa
     4321 gactgtatgc gccagcaacc tcactatctc gaattgttaa gcccggcccg tgacgccgca
     4381 attgctcgcg aagcgatttt gcatggcgca gatgccgtct acatcggcgg acccggtttt
     4441 ggcgcacgtc ataacgccag taacagtctg cgcgatatcg ccgatctggt cccgtttgct
     4501 caccgttacg gcgccaggat ttttgtcacg ctgaatacta tcctgcatga tgatgagctg
     4561 gagcccgcgc agcggttaat caccgatttg tacaataccg gggtggatgc gctgattgtg
     4621 caggatatgg gcattctgga actggatatc ccgccgattg agcttcacgc cagtacacag
     4681 tgtgatattc gcagcgtgga aaaagcgaag tttcttgccg atgtcggttt ttcacagatt
     4741 gtactggcgc gcgagcttaa tttgagtcag atagcggcta ttcatcaggc tactgacgcc
     4801 acgattgagt tcttcattca tggcgcgctg tgtgtcgctt attctggaca gtgttatatc
     4861 tctcatgcgc aaaccgggcg cagcgccaat cggggcgact gttcgcaggc ctgtcgctta
     4921 ccgtatacgt taaaagacga tcaggggcgg gtggtctctt acgaaaaaca tttgctatcg
     4981 atgaaagata acgatcaaac ggctaacctt ggcgcgttga tcgatgcagg cgtacgttcc
     5041 ttcaagattg aagggcgcta caaagacatg agctatgtca aaaacatcac cgcgcattat
     5101 cgtcagatgc tggacgcgat tatcgagcaa cgtggcgatc tggcgcgtgc atcggttggt
     5161 cggaccgagc acttttttgt tccctccacg gagaaaacct tccatcgcgg cagcaccgac
     5221 tattttgtta acgcgcgtaa aggcgatatt ggcgcatttg attcaccaaa atttattggc
     5281 ttgccggtag gcgaggtgct gaatgtggcg aaggattatc tcgacgtaga agcgacggag
     5341 ccgttggcga atggcgatgg tctgaacgtg ttgattaagc gtgaagtggt gggttttcgc
     5401 gccaatacgg tggagaaaac cggtcataac cgctaccgcg tttggccaaa tgatatgcct
     5461 gccgacctgc ataaagtccg tccgcatcat ccgttgaatc gtaatctgga ccataactgg
     5521 cagcaagcgc tgacaaaaac ctccagtgag cgccgtgtgg cggttgatat catgctgggc
     5581 ggctggcagg aacagcttat tctgacactg accagtgaag acagtgtctg catcacgcat
     5641 acgcttgacg gggtatttga ggaagccaac aactctgaaa aagcgttgaa taacctaaca
     5701 gccggactgg cgaagctggg acaaacgctt tactacgcgc gtgatatgca ggtgacatta
     5761 ccggcggcgt tgttcgtgcc aaatagcctg ctcaatcagt tccgtcggga ggcgattgat
     5821 atgcttgacg cggcgcggct ggcccattat caacgaggtc gtcggaaacc cgtggcgcag
     5881 cctgcgcccg tctatccgca aacgcatctc agctttctcg ctaatgtcta caaccacaaa
     5941 gcgcgggaat tttatcaccg ttacggcgta caattgattg atgcggccta tgaggcgcat
     6001 caggagaagg gcgaggtacc ggtcatgatc accaaacact gcctgcgttt tgcgttcaac
     6061 ctttgtccaa agcaggcgaa aggaaatatt aagagctgga aagccacgcc gatgcagttg
     6121 gtgcatggtg atgaggtact gacgctaaaa ttcgactgcc gcccttgcga aatgcatgtc
     6181 attggcaaaa ttaaaaacca catcttaaaa atgccccagc ccggcagcgt tgtcgcttca
     6241 gtgagccctg aagcgctgat gaaaacgctg ctgaagcgca ggggcgttta attaacgaaa
     6301 atagctctct ggtttgcgcg atttctgcca gttgtggtgc tcgcgcaagc cttccgcgga
     6361 ttcttccgct gccgcccgta attcatcgct gtcggcttcg tgtctaagct ggtgccctcc
     6421 cgtcgcaaac catacgaatg cgtggtcttg ctgtttcgcc agtaactggc ctgaaaatag
     6481 cgcacaggtc agtaaaacta ctgataacgt ttttgtaagc atcatgccac cttccagtta
     6541 cgtcgtgagg ctatgatgcc aataatttct ttgagttatt attcaacact tcaaattagc
     6601 gaaaacggtt tgtcaataag tgcgataagt tgtatgagaa aatatattta tactcagtat
     6661 gtcaattata aaaataacga gccaattcgt tccatagtaa atccattatt ccctggaagc
     6721 atatttttaa aggtattgta ttagatggtt ttggtattgc caggggattg taaatccata
     6781 ctatttatgg tgtggtcaac tctggtaatg agcctcattt tttgttgttt caacgagtga
     6841 agataaatct tcagaaaaaa ggc
//
LOCUS       DAJVKX010000179         6863 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.179, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000179 DAJVKX010000000
VERSION     DAJVKX010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6863
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.179"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            210..2399
                     /locus_tag="OPY25_004137"
     CDS             210..2399
                     /locus_tag="OPY25_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HCS0929599.1"
                     /translation="MSFVSTNNKSGMGGLTTTTPPITGESGGVTADSVAGSVADAAEA
                     AVEQAAGSLFGALPEPSGLVKAAVAAAQAAAAAGMAQDAVSAIVSAVAGGPGAHNVTV
                     SGSAVPPGALLFASLDGGETLSELFSYVVQLKTPDTLNLGYVSPAANLPLKPMVGKDL
                     CVNIELDGGGKRHISGLVTAARVVGHEGRSVTYELRMEPWVKLLTHTSDYKAFQNKTV
                     VDILDEVLAEYPYPVEKRLVESYPVRTWQVQYGETDFDFLQRLMQEWGIYWWFEHSED
                     SHTLVLADAISAHKACPDSPLVEWHQEGLKLDKEFIHTITANESLRTGQWVLDDFDFT
                     KPRSLLANTVANPRETGHATYEHYEWPGDYFDKSEGEMLTRIRMEAQRSPGSRVLGGG
                     NIRTLMTGYTFTLENYPTAEVNQEYLLMQTLLFVQDNAQHSGQDQHFTFSTRFELHPT
                     REVFRPQRTVSKPHTKGPQSAIVTGPAGQEIWTDQYGRVKVQFGWDRYGKMDENSSCW
                     IRVSYPWAGKGFGMIQIPRIGQEVLVDFKNGDPDLPIIVGRTYNQDTMPPWGLPGMAS
                     QSGIFSHSLYGGPTNGNMLRFDDKTGAEEVKFHAEKDLNTTVKNNETHTVMVDRTKTI
                     IKNETNSIGEDRNTTVTKNDGLSVKLAQTINIGTTYRLDVGDQFTLRCGNAALVLHKD
                     GSIEFCGKQLMLHTSDVMQLIGKGIDMNPDGGTAVTADDIAPLPTSE"
     gene            2423..2869
                     /locus_tag="OPY25_004138"
     CDS             2423..2869
                     /locus_tag="OPY25_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB-related protein"
                     /protein_id="HCS0929600.1"
                     /translation="MDRPYRIQEGCFVLPETFTDRSVNIFILEGNERTSPSLNISRDT
                     LKPDEDLPAYIDRQIALMKKNLGQHRVLSRAPAQAGTGNDALMGEQIAATHKSGKTEV
                     YQRQAGFIATPGKVLVFTLTSPRPFDDKADLLWNTWLAGFQPDKNE"
     gene            2888..>6863
                     /locus_tag="OPY25_004139"
     CDS             2888..>6863
                     /locus_tag="OPY25_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HCS0929601.1"
                     /translation="MYEAARVDDPIYHTSALAGFLIGAIIGIAIIALAAFAFFSCGFL
                     AGLILGFMADQIASGVLQLGEAIGRSIHHTAGKILTGSENVSTNSRPAARAVLSTVKC
                     DNHIAEKRIAQGSGNIYINSQPAARKDDHTECDAVVEDGSPNVFLGGGTQTVLEISSE
                     IPDWLRKVVDVLFVVASLLGGLAGAWRQAAKLGTKFGTKCAAKFIGGELTGMAVSEAI
                     SGLFSNPVDVTTGQKILLPETDFTLPGRLPVTCSRFYASHLETVGLLGQGWRLNWETS
                     LREDDEHITLTGVQGRELRYPKMMLTPGHQIFGPKEQLYLSRLHDGRYVLHYTDRSYY
                     VFGDFDSDGMAYLLFMETPHRQRIVFGHEGGRLVRIASSSGHHLLLHRTQTPAGERLS
                     RIELVQGGTCGNLVEYRYDDNGQLTGVVNRAGTQVRQFAYENGLMTAHSNAAGFTCRY
                     RWQELDGAPRVTEHDTSDGEHYRFDYDFAAGTTTVTGRQGESWQWWYDRETYITAHRT
                     PGGGMYRFTYNEDHFPVNIGLPGGRTVAYEYDIQNRVVKTTDPEGRVTQTQWNGEFDE
                     ITRTALDDDAVWKTQYNAHGQPVQETDPEGRVTQYAYDEQGQMCSRTDAAGGTVVTAF
                     DSRGQMTRYTDCSGRSTGYDHDEDGNLTRVTDAEGKVVRISYNRLGLPETVNSPGKQQ
                     DRYTWNALGLMSSHRRITGSVESWRYTPRGLLAAHTDEEKRETRWQYTPEGRVTALTN
                     GNGAQYRFSHDADGRLMREVRPDGLSRTFILDDSGYLTAIQTTGTQGGVRRETQQRDA
                     LGRLLRTENEHGQRTFSYNRLDQITAVTLTPTEAGQQQHRMQADTVRFEYDRSGWLTA
                     EHAGNGSICYQRDALGNPTDITLPDGQHLTHLYYGSGHLLQTALDGLTVSEYERDSLH
                     RQIMRTQGQLATYSGYDDDGLLSWQRSLAPGSAPVLPGQRPARQGCVTSRDYYWNNHG
                     EVGTIDDGLRGSVVYSYDRSGYLTGRSGQMYDHDRYYYDKAGNLLDNEGQGPVMNNRL
                     PGCGRDRYGYNEWGELTTRRDQQLEWNAQGQLTRVISGNTETHYGYDALGRRIRKATY
                     GRHTGHTARSRTDFVWEGFRLLQENVQQQGWRTYVYDAEQPYTPVASVTGRGESRQVW
                     YYHTDVTGTPQEVTAADGTLVWAGYIRGFGENAADISNSGAYFHQPLRLPGQYFDDET
                     GLHYNLFRYYAPECGRFVSQDPIGLRGGLNLYAYCPNPLTWIDPLGLDLHHIIPQEVW
                     KTFKTDLKKVTGYVQNVTKKAMDVTNLIDLDKPFHGNHPAYSAYVKDKISELIKNKKL
                     SLTEL"
BASE COUNT         1597 a         1776 c         2190 g         1300 t
ORIGIN      
        1 tgttatattc atttccttat ttatgtaatt cagtatttat gttatgtgct aatttttgtg
       61 tttttatttt catggctctt gtcagcaata taccctgttc ttctggtaaa tatttaaata
      121 taacaggctg gttgcattat aaagtgcggg gcactgtttc ctgacggtga gtctatttat
      181 tttaatccgg tattaaagga gtcactacca tgagttttgt atccacaaat aataaatccg
      241 gtatgggagg gctgacgaca accacgccgc cgataaccgg agaaagtggc ggtgtcaccg
      301 cagattcagt cgccggaagc gtggcagatg cggcagaagc cgccgtggaa caggctgcgg
      361 gatcgctgtt tggcgcattg ccggagccat caggactggt gaaagccgcg gtggcagcgg
      421 cgcaggctgc cgccgctgca ggtatggcgc aggatgcggt atcggccatc gtctctgctg
      481 ttgcaggcgg gccgggggcg cataatgtga cggtcagcgg cagcgccgta ccgccgggcg
      541 cattactgtt cgccagcctg gacggcggcg aaacattaag tgaactgttc agttatgtgg
      601 tacagctaaa aacgcccgac accctgaatc tgggctatgt ctccccggcg gccaacctgc
      661 cgctcaaacc gatggtgggc aaagatctgt gcgtcaacat cgaactggat ggtggcggta
      721 aacgacatat cagcgggctg gtcacggcgg cgcgggtggt gggccatgaa gggcgttcgg
      781 ttacctatga gctgcgtatg gagccgtggg taaaactgct gacccatacc agcgactaca
      841 aagcattcca gaataaaacc gtggtggata ttctggatga ggttctggcg gaatacccct
      901 acccggtgga aaagcggctg gtggaaagct acccggtacg cacctggcag gtgcagtacg
      961 gtgaaactga ttttgatttt cttcagcgac tgatgcagga gtggggcatc tactggtggt
     1021 ttgagcacag cgaggacagc cacacgctgg tgctggcgga tgccatcagc gcccacaaag
     1081 catgtccgga ctcgccgctg gtcgagtggc accaggaagg gctgaagctg gacaaggagt
     1141 ttatccacac tatcacggca aacgagagtc tgcggactgg ccagtgggtg ctggatgatt
     1201 tcgattttac gaagccacgt tcattgctgg caaacaccgt ggcaaacccg cgtgaaaccg
     1261 gtcatgccac ctacgagcat tatgagtggc cgggagacta cttcgacaag agtgaaggcg
     1321 agatgctgac gcgcattcgt atggaagcgc agcgcagccc cggcagtcgg gtgctggggg
     1381 gagggaatat ccgcacactc atgaccggtt ataccttcac gctggaaaac tatcccaccg
     1441 ccgaagtcaa tcaggaatac ctgctgatgc agaccttgct gtttgtacag gacaacgcgc
     1501 agcacagcgg gcaggaccag cactttacct tttccacccg ttttgaactg cacccgaccc
     1561 gtgaggtgtt ccgcccgcag cggacggtga gcaaacccca caccaaaggg ccgcagagcg
     1621 ccatcgtcac cggcccggcg ggccaggaaa tctggacgga tcagtacggg cgggtaaagg
     1681 tacagtttgg ctgggatcgc tacggcaaaa tggatgaaaa cagctcctgc tggatacgcg
     1741 tcagctaccc atgggcgggc aaaggcttcg ggatgatcca gatcccgcgt atcggccagg
     1801 aagtgctggt ggatttcaaa aacggcgatc cggatctgcc gatcatcgtg gggcgtacct
     1861 acaaccagga caccatgccg ccgtggggac tgccgggaat ggcgtcgcag agcgggatct
     1921 tcagccactc gctgtatggc gggccaacga acggcaacat gctgcgtttt gacgacaaaa
     1981 cgggcgcgga ggaagtgaag ttccacgcgg aaaaagatct caacaccacg gtgaagaata
     2041 atgaaacgca tacggttatg gtggatcgca ctaaaaccat tattaaaaat gaaaccaaca
     2101 gtattggtga agacagaaac accacggtaa cgaagaatga cggcctttcc gtaaaactgg
     2161 cgcagacgat caatatcggc accacttatc gtttagatgt tggcgatcaa ttcacacttc
     2221 gctgcggcaa tgcggcgctt gttttacata aggacggctc cattgagttt tgtggcaagc
     2281 aactgatgtt gcataccagc gatgtcatgc aactgattgg taaaggtatt gatatgaacc
     2341 cggatggcgg cacagccgta accgccgatg atattgcccc ccttcccacc tctgagtgat
     2401 ctgaattaaa cctggagttc tcatggatcg accataccgc atacaggaag ggtgttttgt
     2461 cctgcctgaa acatttacgg atcgcagcgt caatattttt atcctggagg gcaatgaacg
     2521 aacatcgccc agcctgaata tttcccgcga tacgctaaaa cctgatgaag acctgcccgc
     2581 ctatattgac cgccagattg cgctgatgaa aaaaaatctc ggtcagcacc gggtattgtc
     2641 gcgagcgcct gcacaggcag gaacgggcaa tgatgccctg atgggggaac aaattgccgc
     2701 cacccataaa tccgggaaaa cggaagtgta ccagcgtcag gccgggttta ttgcaacccc
     2761 tggcaaggta ctagtcttca ccctgaccag tccccgtcct tttgatgata aagcagacct
     2821 actctggaac acctggctgg caggctttca gccggataaa aacgaataat cacacggagg
     2881 tgtgaccatg tatgaagcag cccgtgtgga tgaccctatc taccacacca gtgcgctcgc
     2941 cgggtttctt atcggcgcta tcatcggcat cgccattatc gcgcttgccg cctttgcctt
     3001 ctttagctgc ggttttcttg ccgggctgat tctgggtttt atggccgatc aaatagcctc
     3061 cggggtattg caactgggcg aggccatcgg gcgctccatc caccacacgg caggaaaaat
     3121 cctcaccggt tcggagaatg tcagcaccaa cagtcgcccg gcggcgcgcg cggtactgag
     3181 tacggtgaaa tgcgataacc atatcgcaga aaaacgcatc gcccagggtt ccggcaatat
     3241 ttacatcaac agccagcctg ccgcccgtaa ggatgaccat accgaatgcg atgcggtggt
     3301 tgaagacggt tcgccgaatg tgtttctcgg cggcggcaca cagacggtac tggaaatcag
     3361 ttctgaaatt ccggactggc tgcgcaaggt ggtggatgta ttgtttgtcg tggcgagtct
     3421 gctcggcggg ctggccgggg cgtggcggca ggcggcaaag ctggggacga aatttggcac
     3481 taaatgtgcc gctaagttta tcggcgggga gcttaccggg atggccgtga gtgaggctat
     3541 cagcgggctg ttcagcaatc cggtggatgt gaccaccggg cagaaaatcc tgctgccgga
     3601 aacggacttc accctgcccg gtcgcctgcc ggtcacctgc tcgcgttttt acgccagcca
     3661 cctggaaacc gtgggactgt tgggacaggg ctggcggctg aactgggaaa ccagcctgcg
     3721 cgaggacgat gaacacatca cgctgaccgg cgtacagggg cgggaactgc gttacccgaa
     3781 aatgatgctg acgcccggcc accagatatt tggcccgaaa gaacagttat acctcagccg
     3841 cctgcatgac gggcgttacg tgctgcatta caccgatcgc agctattacg tatttggtga
     3901 ttttgacagt gacggcatgg catacctgct gtttatggag acgccgcacc gccagcgcat
     3961 tgtcttcggg cacgaaggag gcagactggt acggatagcc tccagcagcg ggcatcacct
     4021 gttactgcac cgcacacaga ccccggcagg ggagcggctg tcgcgaattg aactggtgca
     4081 gggcggcacc tgtggcaatc tggtggagta ccggtatgac gataacggtc aactgaccgg
     4141 cgtggtgaac cgggcgggaa cgcaggtgcg gcagtttgct tatgaaaacg ggctgatgac
     4201 ggcgcacagc aatgcggcgg ggttcacctg ccgctaccgc tggcaggaac tcgacggcgc
     4261 gccgcgcgtg acggagcacg acaccagtga cggtgaacat taccgctttg actatgattt
     4321 tgccgcaggc accaccaccg tcaccggcag gcagggggag tcatggcagt ggtggtacga
     4381 cagggagacg tatatcaccg cgcaccggac gccgggcggt ggaatgtacc gcttcacgta
     4441 caacgaagac cacttccctg tcaacattgg gctgcccggc ggtcgcacgg tggcgtatga
     4501 atatgacatc cagaaccggg tggtgaagac gacagatccg gaaggccggg tgacgcagac
     4561 gcagtggaac ggcgagttcg acgaaatcac gcgcacggcg ctggacgatg acgctgtctg
     4621 gaaaacgcag tacaacgccc acggccagcc agtgcaggag acggacccgg aagggcgggt
     4681 gacgcagtac gcttacgatg aacaggggca gatgtgcagc cggacggatg cggcgggcgg
     4741 cacggtggtg acggcgttcg acagccgggg gcagatgacg cggtacaccg actgttcagg
     4801 gcgtagcaca ggatatgacc acgatgagga cggcaacctg acgcgggtga cggacgcgga
     4861 agggaaggtg gtacgcatca gctacaaccg acttgggttg ccggagacgg tgaactcacc
     4921 ggggaaacag caggacaggt atacctggaa tgcgctgggg ctgatgagca gccaccggcg
     4981 catcacgggg agcgtggaga gctggcggta tacgccgcgc ggtctgctgg cggcgcacac
     5041 ggatgaggag aagcgcgaga cgcgctggca gtacacgccg gaaggccggg tgaccgcgct
     5101 gaccaacggc aacggggcgc agtaccggtt cagtcacgat gcggacggca ggctgatgcg
     5161 tgaggtgcgc ccggacggac tgagccgtac ttttatcctg gacgacagcg gttatctgac
     5221 ggcgatacag accacgggta cgcagggcgg cgtgcggcgg gagacgcagc agcgggatgc
     5281 gctgggccgt ctgttacgga cggagaatga acacggccag cggacgttca gctacaaccg
     5341 gctggaccag ataacggcag tgacgctcac gcccacggag gcggggcaac agcagcaccg
     5401 gatgcaggcc gacacggtgc gttttgagta tgaccgcagc ggctggctga cggcggagca
     5461 cgcggggaac ggtagcatat gttatcagcg cgacgcgctg ggcaacccga cggacatcac
     5521 gctgccggac gggcagcacc tgacgcatct gtattacggg agcgggcatc tgttacagac
     5581 ggcgctggac ggcctgacgg tgagcgagta tgagcgcgac agcctgcacc gtcagataat
     5641 gcgcacgcag gggcagcttg cgacgtacag cggctatgac gacgacgggc tgctgagctg
     5701 gcagcgcagc ctggcgcccg gcagtgcccc tgttcttccc ggccagcgcc cggcgcggca
     5761 gggctgcgtg acgtcgaggg actattactg gaacaaccac ggcgaggtgg gcacgattga
     5821 cgacggcctg cgtggcagcg tggtgtacag ctatgacaga agcggttacc tgaccgggcg
     5881 ctcaggtcag atgtatgacc atgaccgtta ttattacgat aaggcgggca acctgctgga
     5941 taacgaaggg cagggtccgg tgatgaacaa ccggctgccg ggctgtggtc gtgaccgtta
     6001 cggttataac gagtggggcg agctgaccac gcggcgcgac cagcaactgg agtggaacgc
     6061 gcaggggcag ctgacgcggg tcatcagcgg caacacggag acgcactacg gctacgatgc
     6121 gctggggagg cgaatccgca aggcgacgta cgggcggcac acgggccata cggcgcggag
     6181 ccggacggac tttgtgtggg aggggttcag gctgttgcag gagaacgtgc agcagcaggg
     6241 ctggcggaca tatgtgtacg atgcggaaca gccgtacacg ccggtggcga gcgtgacggg
     6301 gcggggagaa agcaggcagg tgtggtatta ccacacggac gtgacgggca cgccgcagga
     6361 ggtgacggcg gcggacggaa cgctggtgtg ggcggggtat atcagggggt ttggagagaa
     6421 tgcggcggac atcagcaaca gcggggcgta ctttcaccag ccgctgcggc tgccggggca
     6481 gtattttgac gacgagacgg ggctgcatta caatctgttc agatattatg caccggagtg
     6541 tggacggttc gtcagtcagg atccgattgg gttaaggggc gggttaaacc tgtatgcgta
     6601 ctgccctaat ccactgacat ggatagatcc tctgggactg gatttacacc atataattcc
     6661 gcaagaggtt tggaaaactt ttaaaacgga tttaaaaaaa gtcaccggat atgtgcaaaa
     6721 cgtcacgaag aaagcaatgg atgtaacaaa cttaattgat ctggataaac ctttccatgg
     6781 taatcatcct gcctatagtg cttatgtaaa agataaaatt agtgaactta taaaaaataa
     6841 aaaattaagt ttaactgagc taa
//
LOCUS       DAJVKX010000180         6730 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.180, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000180 DAJVKX010000000
VERSION     DAJVKX010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6730
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.180"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            68..2914
                     /gene="rcsC"
                     /locus_tag="OPY25_004140"
     CDS             68..2914
                     /gene="rcsC"
                     /locus_tag="OPY25_004140"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HCS0929602.1"
                     /translation="MKYLASFRTTLKVSRYLFRALALLIWLLIAFVSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLTAENGVMSSRARDDKMVVPDF
                     EPLFADSDCAAMGSAWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     REMPVERDDALKALHERIMKYRNAPQEESGNNLFWISQGARQGVGYFYALTPVYLANR
                     LQALLGVEQSIRMENFFTPGSLPMGVTIIDENGHSLISLTGPDGIIKAEPRWMQERSW
                     FGYTPGFRELVLKKSLPPSSLSIVYSVPVDLVLERIRILILNAILLNVLVGAGLFTLA
                     RMYERRIFIPAESDAQRLEEHEQFNRKIVASAPVGICILRTIDGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSTRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVSLNGDPMRLQQVISNLLSNAIKFTDIGCIVLHVRCDGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTLRIPLYGAQYPVKKSVEGLAGTCCWLAVRNTSLCQFIETSLARSGVHTQRYEGQE
                     PAADDILIVDDALEHTWQGRAAVVFCRRHIGIPLERAPGEWVHSVASVHELPALLARI
                     YSIELDSEALSSALPTTDKTADSNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNAIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVVGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDALKQTLAVYAERVRKTRA"
     gene            complement(3017..3667)
                     /gene="rcsB"
                     /locus_tag="OPY25_004141"
     CDS             complement(3017..3667)
                     /gene="rcsB"
                     /locus_tag="OPY25_004141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HCS0929603.1"
                     /translation="MNNMNIIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPTDKE"
     gene            complement(3684..6353)
                     /gene="rcsD"
                     /locus_tag="OPY25_004142"
     CDS             complement(3684..6353)
                     /gene="rcsD"
                     /locus_tag="OPY25_004142"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HCS0929604.1"
                     /translation="MSQSDTTVSTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIHKRVDTWRYVTWQIYDNIAATTTPSTGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDSATLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLILIST
                     LPLKDLSSGFKESTIGNIVDSRRAEMLQQANALDERESFSSLRKLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRIEPDATQTTGRSSEKEAPDSVTISFNG
                     SKIEISSALNSTGMRLIWQVPFGTLLLDTLQNILLPLLLNIGLLALALFGYATFRHQP
                     GRSTESTSGNAANNELRVLRAINEEIVSLLPLGLLVYDQEGNRTVISNKIADHLLPHL
                     NLQNITSMAEQHQGVIQATINNELYEIRLFRSQIAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRAAFMQNISNTLKEPVRQLAVNAAAVTTPESLKLADQADVLVRMIDE
                     IQLANMLENDAWKSEATLFSLQDLIDEVVPEVLPAIKRKGLQLLINNHLSGNDERWGD
                     RDALRRILLLLIQYAVTTTAMGKITLEVEQDESIAERLTFRILDTGEGVTLNEIDNLH
                     FPYMNETQGDRYGKANPLTFWLCNQLARKLGGHLNIKARETLGTRYTVHVKMLPHDQH
                     TQVEERLLDDVSVMVDVTSNEVRAIVLRQLENWGATCITPDERQISQEYDLFLTDNPS
                     NLTASGLLLSDDESGVRKIGPGQLRVNFNMSNAMQEAVLQLIEEQLAQEEIPASPLGG
                     DENAELHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPGK
                     QLCVTLEHLIREKDAPGIEKYISDIDAYVKSLL"
BASE COUNT         1556 a         1661 c         1813 g         1700 t
ORIGIN      
        1 cgggctacgt catttaccgc taccttagtc acactctatt tacatcctga ggcggagctt
       61 cgcccctttg aaataccttg cttcctttcg aactacgctg aaagtctcgc gctacttatt
      121 cagagcgtta gcgttactca tttggctctt aatcgccttt gtttcggtgt tttacatcgt
      181 caatgccctg caccagcggg agtctgaaat tcgtcaggag ttcaacctta gctccgatca
      241 ggcgcagcgt tttatccagc gcacgtcgga tgtgatgaaa gagctcaaat atatcgccga
      301 gaaccgttta acggcggaaa acggcgtcat gtcgtcgcgt gcgcgtgatg acaaaatggt
      361 ggtgccggat tttgaaccgc tattcgccga ctcagactgt gcggcgatgg gctccgcctg
      421 gcgcggctcg ctggagtcgc tggcctggtt tatgcgttac tggcgcgaca acttttcagc
      481 ggcgtatgat cttaaccgcg ttttcctgat tggcagcgat aacctctgta tggcgaattt
      541 cggcctgcgt gaaatgcccg tggagcgcga tgatgcgtta aaagcgttac atgagcggat
      601 tatgaaatac cgcaacgcgc cgcaggaaga aagtgggaat aaccttttct ggataagcca
      661 gggcgcgcgt cagggcgtgg gctactttta tgcgctgacg ccggtgtatc tggccaatcg
      721 tctgcaggcg ctgctgggcg ttgagcagtc catccgtatg gaaaattttt tcacgcccgg
      781 cagtttgccg atgggcgtca ctattattga tgagaacggc cattcgctga tttcgttgac
      841 cggtcctgac ggcattatta aagcggagcc gcgctggatg caggagcgtt cctggtttgg
      901 ttatacgcca ggttttcgcg aactggtact caaaaaaagc ctgccgccat cctcgctcag
      961 tattgtctat tctgtgcctg tagatttagt cctggagcgt attcgtattc ttatcctgaa
     1021 cgctatcctg ctgaacgtgc tggtgggcgc agggctgttt acgcttgcgc ggatgtatga
     1081 gcggcgaatt ttcattccgg cggagagcga tgcccagcgt ctggaagaac atgaacagtt
     1141 caaccgtaaa atcgttgcct ccgcgccggt ggggatctgt attctgcgca ctattgatgg
     1201 tgtcaatatt ctgagtaacg aactggcgca cacctacctg aacatgctca cgcatgaaga
     1261 cagacagcgc ctgacgcaaa tcatttgcgg ccagcaggtc aactttgttg atgtattgac
     1321 cagcaataat accaatttgc aaattagctt cgtccattcc cgctatcgta atgaaaacgt
     1381 cgcgatttgc gtgttggtag atgtgagtac gcgcgtcaaa atggaagagt cgctgcaaga
     1441 gatggcgcag gcggcggagc aggcaagcca gtctaaatcc atgttccttg caacggtcag
     1501 ccatgaattg cgcacaccgc tgtacggtat catcggcaat ctcgatctgc tgcaaaccaa
     1561 agagctgcca aaaggcgtgg atcgtctggt cacggcgatg aataactcct ccagtctgtt
     1621 gctgaaaatt atcagcgaca ttctcgactt ctcgaaaatt gagtcggaac agctaaagat
     1681 tgagccgcgc gaattttcac cgcgagaggt gatgaaccat atcaccgcca attatctgcc
     1741 gctggtggtg cgtaagcaac tcggcctgta ttgttttatt gagcctgacg tgccggtatc
     1801 gctgaacggc gacccgatgc gtttacagca ggttatttca aacctgttga gcaacgccat
     1861 taagtttacc gatattggct gcatcgtgct gcatgtgcgc tgtgatgggg attatctcag
     1921 cattcgcgtg cgggataccg gggttggtat tccggcaaaa gaggtggttc gcctgttcga
     1981 tcccttcttc caggtgggaa ccggcgtaca gcgtaacttt caggggaccg gtctggggct
     2041 ggcgatttgc gaaaaattga tcagcatgat ggacggcgat atttccgtcg attcggagcc
     2101 gggcatggga agccagttta cgttgcgcat cccgctttat ggcgcgcaat accctgtgaa
     2161 aaagagcgtg gaaggactcg ccggaacctg ctgttggctg gcggtgcgca atacttcttt
     2221 gtgccagttt attgagacca gtctggcgcg tagcggcgtt catacgcagc gttatgaagg
     2281 gcaagaaccc gccgcagacg atattttgat tgtcgatgac gcgctggagc atacctggca
     2341 ggggagggcg gcggtcgtct tttgccgccg tcatatcggg attccattgg aaagagcgcc
     2401 tggcgagtgg gtgcatagtg tggcgtcggt gcatgagttg cccgcgctgt tggcgcgtat
     2461 ctatagtatt gagctggata gtgaagcgct ttccagcgca ttgccgacga cggataaaac
     2521 cgcagattca aatgacgaca tgatgattct ggtcgttgac gatcatccga tcaatcgccg
     2581 cttgctggcc gatcaactgg gatcgctggg gtatcagtgt aagacagcca atgatggcgt
     2641 ggacgctctg aatgtgctga gtaaaaatgc tatcgatatt gttctgagcg atgtgaacat
     2701 gccgaacatg gacggctatc gcctgacgca gcgtatccgt cagcttgggc tgacgctgcc
     2761 ggtcgtcggc gtgacggcga acgcgctggc ggaagagaaa caacgttgcc tggagtccgg
     2821 tatggatagc tgtttgtcga agcctgtgac gctggatgcg ttgaaacaga cgctggcggt
     2881 gtatgccgag cgggtacgta aaacgcgggc ataaaaaatg ccggatggcg gcgtcgcctg
     2941 tccggcctgt aaaagatgag tcgactggta ggcctgataa gcgtagcgcc atcaggctgg
     3001 gtaacataaa agcgatttat tctttgtctg tcggactcag ggtgacggaa gagagatagt
     3061 tgagcagcgc gatatcattc tctacgccca gtttcatcat cgccgatttc ttctggctgc
     3121 tgatggtctt aatgctgcgg ttgagcttct tggcgatttc ggtgaccagg aagccctcgg
     3181 cgaacaggcg taatacttcg ctctcttttg gcgacaggcg cttatcgccg taaccgcctg
     3241 cgctgatttt ctccagcaga cgagaaacgc tttccggggt gaattttttg cctttttgca
     3301 gcgcggccag cgccttaggc agatcggttg gcgcaccctg tttgagtacg atcccttcaa
     3361 tatcaagatc caacacggcg ctcaggatcg ccggattgtt gttcatggtc agaacgataa
     3421 tagacaggct cggaaaatga cgcttgatgt acttgatcaa ggtgatccca tcgccgtatt
     3481 tatctcccgg catggagagg tcagtgatca acacatgcgc atctaatttc ggcaggttgt
     3541 tgatcaatgc tgtggaatct tcaaattcgc cgacaacatt cacccactcg atttgttcaa
     3601 gtgatttgcg aataccgaac agtacaatcg ggtggtcatc ggcaataatt atgttcatat
     3661 tgttcatgta ttgggctact ttgctacagc aagcttttga cgtaggcgtc aatgtcgctg
     3721 atatattttt ctatacctgg agcatctttc tcacgaatca gatgttccag cgttacacat
     3781 aactgcttgc cgggtaccag attaagcatg gcaaacaccc ctttcaggcg gtgggccgtt
     3841 tgggccagcg cagcgaaatc gctggttgcc gcctcagtat acaacctctt aacatcatcc
     3901 ggtactgtgt ctacaaatag cgcataatag ccgctggcat gaagctcggc attttcatct
     3961 ccgccgagcg gggaggcggg aatctcttcc tgcgccagct gctcttcgat aagttgtagt
     4021 acagcttcct gcatagcatt gctcatatta aagttgacgc gcaactgacc cgggccaatt
     4081 ttccgcacgc ctgactcatc atcgcttaaa agcaagcccg aggcagtaag attagacgga
     4141 ttatccgtta aaaagagatc atattcttga cttatctgcc tttcatccgg cgtgatgcag
     4201 gtggcgcccc agttttctaa ctgacgcagc acaatcgcgc gaacctcgtt ggacgtcaca
     4261 tcgaccatca cgctcacgtc gtccagcagg cgctcttcga cctgagtatg ctgatcgtga
     4321 ggaagcattt tgacatgaac ggtatagcgc gtgcccagcg tttctcgcgc tttaatgttg
     4381 agatgaccgc ccagtttgcg cgccagttga ttgcacagcc agaaggtgag cggattcgct
     4441 ttgccgtaac ggtcgccctg cgtttcattc atatacggga aatgcagatt atcaatctcg
     4501 tttaacgtta cgccttcgcc cgtatccaga atacggaaag tcagacgctc cgcgatagat
     4561 tcatcctgct cgacttcaag cgtaatttta cccatagcgg tcgtcgtgac ggcatactga
     4621 atcaacagca gcaaaatccg gcgcagggcg tcgcgatcgc cccagcgttc atcgttgccg
     4681 ctaagatggt tattaatcag cagttgcagc cctttacgct taatggcggg cagcacttcc
     4741 ggcacgactt cgtcaataag atcctgcagg gagaacagcg tggcttcgct tttccatgcg
     4801 tcattttcca gcatattcgc cagttggatt tcatcgatca tacgtactaa tacatccgcc
     4861 tgatccgcca gtttcaggct ttccggcgtg gtgactgccg cggcgttaac cgccagttgg
     4921 cgtacgggct ctttaagcgt gttgctgata ttttgcataa aggcggcgcg gccctgctga
     4981 ttcttctcat acaaacgctg cgcctgttta agcttcttat tcaccagcac ttcccggtcc
     5041 tgatcgcgaa taataaagat ctgcgtgcgg ggggcgatct ggctgcgaaa cagacggatc
     5101 tcatacagtt cgttattaat tgtcgcctga atcacgccct gatgctgctc cgccatgctg
     5161 gtaatatttt gcaggttaag atgcggcaac agatgatcgg cgattttatt gctgatcacg
     5221 gtgcggttgc cttcctgatc gtagaccagc agacccagcg gcagcagaga aacgatctct
     5281 tcattaatgg cgcgtaagac gcgaagctca ttattcgccg cgttgccgga tgtcgattcc
     5341 gtcgaccgtc ccggctgatg acggaacgtg gcgtagccaa ataacgccaa cgccagcagc
     5401 ccgatgttca gcagtaaagg cagcaaaata ttttgcaacg tatcaagcaa aagcgtaccg
     5461 aacggtacct gccagatcag gcgcattccg gtagagttaa gcgctgagga gatctcaatt
     5521 tttgaaccgt taaagctaat cgtgacgcta tctggcgctt ccttttcact gcttcgcccc
     5581 gtcgtctggg ttgcgtcagg ctctatccga aaactgtcca gcggcattcc cggcgggatt
     5641 aaatcattaa tgggcagatc aaacgccacc acggttgcca gatgtcctgg ctgattgaag
     5701 gtcgtgcgca gcgtaaaata gtgaccgttt tgccaggcca gttttcgcaa tgaggagaaa
     5761 ctttcgcgct catccagcgc attcgcctgc tgcaacatct ctgcccggcg ggaatcgacg
     5821 atattgccaa tagtggactc tttaaagccg gaagagagat ctttcaacgg tagggtagag
     5881 ataagaatca ggctgttatc ctgtccgttg aggtaataca ttgaccacgg cacgttttcc
     5941 gcgccccaca gcgtatccag ataagttgac atacgctgcg tcatttccag cgtggcgctg
     6001 tcatgggaac cgaaaatcag cgcttcagtt ttacgtcgcg gcttttcaag ataatacaca
     6061 tcctgtttca gacgcgtttc ctgaagtcct tcacctgtcg atggcgtagt ggtcgcggcg
     6121 atgttgtcat aaatttgcca ggtaacatac cgccaggtgt ccacgcgttt atgaatagcg
     6181 tgagtgatat cgacaatttg atagcttttg tctttcaacc aggcgttgac ggcgctctgt
     6241 accataacgc ccatcgttac cagcagcaca atgatcagca ataagaagaa acgggtaatg
     6301 cttcccggta gaagggagaa tcgggtagag accgttgtgt cagactgact catttatgtt
     6361 tacgacctgt aaaagcaacg ctgaaggtga agggcagtat aaagggtaat gaatgaattt
     6421 ccagactctt acgtcatgcc gggcaactta acacgcgctc cgtcggcggg acgggaaaag
     6481 cgtacaacct tcgcaaaacg gtacaaatat aaagactact tataaatgtt tagcactaaa
     6541 tatcaagaaa ttatttgcta atgtcttatg aacggtcgag caggggaggg tagtgaataa
     6601 ccgtgatagt tttaggcagg tagcataaat cagccgggtg tgtctgaaaa agggtaaaaa
     6661 aaccgaatgc gaagcatccg gttgaaatag gggtaaacag acattcagaa gtgaatgacg
     6721 gtaataaata
//
LOCUS       DAJVKX010000181         6671 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.181, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000181 DAJVKX010000000
VERSION     DAJVKX010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6671
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.181"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..71)
                     /locus_tag="OPY25_004143"
     CDS             complement(<1..71)
                     /locus_tag="OPY25_004143"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462263.1"
                     /note="catalyzes the decarboxylation of oxaloacetate to
                     form pyruvate and carbon dioxide; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit gamma"
                     /protein_id="HCS0929605.1"
                     /translation="MTNAALLLGEGFTLMLLGMGFVLA"
     gene            complement(227..844)
                     /gene="ttdB"
                     /locus_tag="OPY25_004144"
     CDS             complement(227..844)
                     /gene="ttdB"
                     /locus_tag="OPY25_004144"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HCS0929606.1"
                     /translation="MTKKILTTPIKDEDLADIKAGDIIYLNGHIVTCRDVAHRRLIEG
                     GRELPVDVRGGAILHAGPIVRPIKGEDDKFEMVSVGPTTSMRMEKFEKEFIAQTGVKL
                     IVGKGGMGKGTEEGCAEHKALHCVFPAGCAVVAAVCVEEIEDAQWRDLGMPETLWVCR
                     VKEFGPLIVSIDTHGNNLFEQNKIIFNQRKEIVADEICQNVSFIK"
     gene            complement(844..1743)
                     /gene="ttdA"
                     /locus_tag="OPY25_004145"
     CDS             complement(844..1743)
                     /gene="ttdA"
                     /locus_tag="OPY25_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HCS0929607.1"
                     /translation="MSKSEQISHMTDVMAKFVGYTGKVLPDDVTAKLEDLHKKETSKL
                     ADVIFTTMIENQRLAKELDRPSCQDTGVIQFLVECGTNFPLIGELEALLREAVIKATV
                     DSPLRHNSVETFDEYNTGKNVGKGTPTVFWEIVPNSDQCSIYTYMAGGGCSLPGKAMV
                     LMPGAGYEGVTRFVLDVMTSYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHN
                     ENERAASLEKMLEDGINKIGLGPQGMSGNTSVMGVNIENTARHPSTIGVAVNVGCWSH
                     RKGHIVFDKDLNYTITSHSGVNF"
     gene            complement(1776..3044)
                     /locus_tag="OPY25_004146"
     CDS             complement(1776..3044)
                     /locus_tag="OPY25_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13/DASS family transporter"
                     /protein_id="HCS0929608.1"
                     /translation="MEPITLTLCLLVFAIVMFVWEKVPLAVTSMIVCVALVITGVLNI
                     KQAFAGFIDTNVILFVAMFIVGGALFETGMANKVGGVITRFAKTEKQLIFTIMVVVGL
                     MSGVLSNTGTAAVLIPVVIGVAAKSGFSRSRLLMPLVFAAALGGNLSLIGAPGNLIAQ
                     SALQNIGGGFGFFEYAKIGLPMLICGILYFLTIGYRFLPNNATGGEVGSVGEQRDYSH
                     VPQWKQRLSLVVLIATILGMIFEKKIGVSLAVTGCIGALVLVVSGVLTEKQAYKAIDS
                     QTIFIFGGTLALAKALEMTGAGKLVADYVIGMLGQNSSPFMLLIAVFALSVVMTNFMS
                     NTATTALLVPVSLSIAAGMGADPRAVLMATVIGGSCAYATPIGMPANMMVLSAGGYKF
                     VDYAKAGIPLIIVSTIVSLILLPILFPFHP"
     gene            complement(3255..3920)
                     /locus_tag="OPY25_004147"
     CDS             complement(3255..3920)
                     /locus_tag="OPY25_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0929609.1"
                     /translation="MQRPKLGKIKLLSAKEQVAAVLRKAILSRELVEGQEITLEGIAG
                     MVGVSSMPVREAFQILAADGLIKVRPNKGAVVLGINEQTIREHYEIRALLESEAVAKA
                     SRPGTDISRIAEVHYAAEKALAENNSAEYSDLNQAFHMEIWNVAGNEKMKMLLCNMWN
                     GLSMGHKVTEEEYAVISIQEHKSILQALELHDETLARQRMREHIIRSMENMLTRYVGD
                     PSA"
     gene            complement(3907..4536)
                     /locus_tag="OPY25_004148"
     CDS             complement(3907..4536)
                     /locus_tag="OPY25_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCS0929610.1"
                     /translation="MKKIQRTQTRDHITQMLRYEILSGNIKAGEELAQESIAEQLGLS
                     RMPVREALQSLEQEGFLIRLPNRHMQVAHLEADRVSHIFRVIAAMAAEMFSLIPSEVG
                     DALLIRAQALAVAEDKSCELECHAMLISYVNNRYLEKVYQQFLDGYVSYVILHLKKDN
                     QESAQLFAELADVIRQGRRDEIGQVMQRYFLSLAEIMRQHMKDWESAEA"
     gene            complement(4656..5594)
                     /gene="mdh"
                     /locus_tag="OPY25_004149"
     CDS             complement(4656..5594)
                     /gene="mdh"
                     /locus_tag="OPY25_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HCS0929611.1"
                     /translation="MKVAVLGAAGGIGQALALLLKNQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQIAKTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKLPTEVEVPVIGGHSGVTILPLLSQIPGVSFTEQEAAELTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEKGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSTFEQHSLDAMLDTLKKDIQLGEDFINK"
     gene            6008..6478
                     /gene="argR"
                     /locus_tag="OPY25_004150"
     CDS             6008..6478
                     /gene="argR"
                     /locus_tag="OPY25_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HCS0929612.1"
                     /translation="MRSSAKQEELVRAFKALLKEEKFSSQGEIVLALQDQGFENINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVRDLYEAILELFEQEL"
BASE COUNT         1729 a         1768 c         1522 g         1652 t
ORIGIN      
        1 gccagcacga atcccatgcc gaggagcatc agagtgaagc cttcacctaa tagcagagct
       61 gcattagtca taaaatagcc ttcaggcagg aggcacgata atggggctat ttatgacgat
      121 gaaataataa gggtggattt ccctgagccg ccccggccag agcccttggt tattattatc
      181 gtcataacgt attaccacca ttatcgtgca atttacgtaa tcaggtttat ttgatgaaac
      241 ttacgttctg gcatatttca tcagcgacga tctctttacg ctgattaaaa ataattttgt
      301 tctgttcaaa cagattattc ccatgggtat caatagaaac aatcagcggg ccaaactctt
      361 taacccgaca gacccacagc gtttccggca tccccagatc gcgccattgg gcatcttcaa
      421 tttcttccac gcacacggcg gctacaaccg cacaaccggc agggaatacg cagtgcagcg
      481 ctttgtgttc agcacagccc tcttcggtac ctttacccat accgccttta cctacaatta
      541 atttcacgcc agtctgcgca ataaactctt tttcgaattt ctccatacgc atgctggtgg
      601 ttgggccaac ggagaccatt tcaaacttat cgtcttcgcc tttaattggg cggacaatgg
      661 ggccagcgtg taaaatagcg ccgccgcgaa catctaccgg aagttcgcga ccaccttcaa
      721 ttaaacggcg atgggctacg tcacggcagg taacaatatg accgttgaga taaataatat
      781 cgccagcctt aatatccgct aaatcttcat ctttaattgg cgtagtcagg atttttttag
      841 tcatcagaaa ttcactccgc tgtgagacgt aatggtgtaa ttcaaatctt tatcgaaaac
      901 gatgtgccct ttacggtgcg accagcagcc gacgtttacc gccacgccga tggtagaagg
      961 atgacgtgcg gtgttttcaa tgttcacgcc cataacggag gtattaccgg acatcccctg
     1021 cggccccagg ccaattttgt taatgccgtc ttccagcatt ttttccagcg aggctgcacg
     1081 ctcattctcg ttatgcgaac cgatcggacg catcagcgct tttttcgata gcagtgccgc
     1141 cgtttcaaca gaggtcgcta cgcccacgcc aaccagcagc ggcggacaag cgttgaggcc
     1201 gtagctggtc atcacatcca gtacaaagcg ggtcacacct tcatagcctg cacccggcat
     1261 cagcaccatc gctttccccg gcagagaaca accaccgccc gccatatagg tataaatgct
     1321 gcactgatcg gaattgggaa cgatttccca gaagaccgtc ggcgtacctt tacccacgtt
     1381 tttaccggtg ttgtattcat caaaagtttc tacgctgttg tggcgcagcg gagaatctac
     1441 agttgctttg atcaccgcct cacgcaacaa cgcttccagc tcgccaatca gcggaaagtt
     1501 cgtcccgcac tccaccaaaa actgaatgac accggtgtcc tggcaggaag gtcgatccag
     1561 ctctttcgcc agacgctggt tctcaatcat ggtagtaaag atgacgtcgg ccagtttact
     1621 ggtctctttc ttatgcaaat cttccagttt tgcagtgaca tcatcaggca aaactttgcc
     1681 ggtatatccc acaaacttgg ccataacgtc ggtcatatgg gatatctgtt cacttttgct
     1741 cataaatgct ccttagtcag aacagcttcc gttaattacg gatgaaaagg gaaaaggatt
     1801 ggcagcagga tcaagctgac aatggttgaa acgataatca gggggatacc ggccttagcg
     1861 tagtcgacaa atttatagcc acccgcggag agcaccatca tgttggcagg cataccgata
     1921 ggagttgcgt aggcgcagga accgccaatg accgtcgcca tcagaaccgc acgcgggtcg
     1981 gcccccatac ctgcggcaat ggacaaactc accggcacca atagcgctgt cgttgcggta
     2041 ttggacataa agttggtcat cacaacggat aaggcgaaaa cggcgatcag caacatgaac
     2101 ggtgaggagt tttgccccag catgccgatt acatagtccg caaccagctt gcctgccccg
     2161 gtcatttcca gcgcttttgc cagcgccagg gtgccgccaa agataaaaat agtctgtgaa
     2221 tcaatggctt tataggcctg tttttccgtg agtacgccgc ttacgaccag cacaagagcg
     2281 ccaatacaac cggtcacggc caggctgaca ccgatcttct tctcaaagat catgccgagg
     2341 atcgttgcga tcaacaccac gagtgagagc cgttgtttcc actgtggaac atggctgtag
     2401 tcacgttgct ccccgacgct ccccacctca ccgccggtcg cattattcgg cagaaagcga
     2461 tagccaatag tcaggaagta gagaatgccg cagatgagca tcgggagacc gatttttgcg
     2521 tattcaaaaa agccaaagcc gccgccaata ttctgtagcg cagactgcgc gataagattt
     2581 cccggcgcgc caattaacga caggttaccg cccaacgcag cggcgaaaac cagcggcatc
     2641 agtagacgag aacgcgagaa gcccgatttt gccgccacgc cgatcaccac cggaatcaaa
     2701 accgcagcgg taccggtgtt agagaggacg ccagacatca aacccaccac caccataatg
     2761 gtgaagatca gctgtttttc tgttttcgcg aagcgcgtga tgacgccgcc cactttgttt
     2821 gccataccgg tctcaaacaa cgcaccgccc acgataaaca tcgcgacaaa gaggatgacg
     2881 ttagtgtcga taaagccagc aaaggcctgt ttaatattca gaacgccggt gataactaag
     2941 gccacgcaga caatcatgga agtgacggcc agcggcactt tttcccatac aaacatgacg
     3001 atagcgaaca ccaataaaca tagggtaagg gtaatgggtt ccatatttat aattatccaa
     3061 tcaatgatat atgatattgt atccaatatt gacgaggaga aattattccc atacaaaaaa
     3121 taagtcaaat cgtttctcag gaaagatgca ggagtgggat ctacatcaag atcgtagttg
     3181 gatcgttact ggacgtgatt aatagaattg aagaattggt tgaagcgcct gcgatactca
     3241 cgcaggcgaa aagatcaggc agaagggtca ccaacatagc gggtcagcat attctccatt
     3301 gagcgaataa tgtgttcgcg catgcgctgg cgtgccaatg tttcatcatg aagttcaaga
     3361 gcttgcagaa tacttttatg ttcctgaatg gaaatcacgg catactcttc ttcggtgacc
     3421 ttatggccca tcgacaggcc gttccacata ttacagagca acattttcat tttttcgttg
     3481 ccagcaacat tccatatttc catatgaaat gcctgattca ggtcggagta ttccgccgag
     3541 ttattttccg cgagagcctt ttcagcggca taatgcacct cggctatccg cgaaatatcg
     3601 gtgccaggac gagaagcttt agccaccgcc tcactttcta acagcgcgcg aatttcatag
     3661 tgttcacgga tcgtttgttc attgatgccc aacaccaccg cccctttatt agggcgcact
     3721 tttatcagcc catccgccgc cagaatctga aacgcctcgc gcactggcat actggacacg
     3781 ccgaccattc cggcaatgcc ttctaacgta atctcttgcc cttccactaa ctccctcgaa
     3841 agaatcgctt tacgcagcac cgccgcgacc tgttctttcg ctgaaagaag cttaatcttc
     3901 cctaacttag gcctctgcac tttcccaatc cttcatatgt tgacgcatta tttctgctaa
     3961 agagaggaaa taacgctgca taacttgccc aatctcatca cgccgcccct ggcgtatgac
     4021 gtcagccagt tcagcgaaaa gctgcgccga ctcctgatta tcttttttca gatgcaaaat
     4081 aacataagag acataaccgt ccaggaactg ctgatacacc ttttccagat agcggttatt
     4141 cacataagaa atcagcatcg catgacactc cagttcgcag gatttgtctt ctgcgacagc
     4201 cagcgcttgc gcacgtatca ggagggcatc gcctacttcg ctgggtatca gcgaaaacat
     4261 ttcggcggcc atcgcggcaa tcacgcgaaa aatatgactc acgcgatcgg cctcaagatg
     4321 cgcgacctgc atgtgcctgt tgggcagtcg gattaaaaaa ccttcctgtt cgagtgactg
     4381 tagcgcttct cgaaccggca ttcgtgaaag accgagctgc tccgcaatac tttcctgcgc
     4441 gagttcttct cccgctttta tattgccgga aagaatttca tagcgaagca tttgcgtaat
     4501 gtgatcgcgg gtttgcgttc tttggatctt tttcacgacg ttctcgttaa taaccgataa
     4561 gacgtgagga gtttagcaga tttagtgctt gatttcgtgg cttgtttata gttaaagaag
     4621 ccggagcaaa agccccggca tcgggcagga acagcttatt tattaataaa atcttcaccc
     4681 aactgaatat cttttttcag cgtatccagc atagcgtcca gcgaatgttg ctcgaaagtg
     4741 ctcagtgtgc cgatggattt acgctcttct acgccgtttt tacccagcag cagcggctga
     4801 gagaagaaac gggcatactg accgtcgcct tccacatagg cgcattccac cacgcctttt
     4861 tcgccctgca gagcgcgaac cagagaaaga ccgaaacgcg cggcagcctg gcccatagag
     4921 agggttgccg atccgccgcc ggctttcgcc tcgacgactt cagtaccggc gttctgaata
     4981 cgtttagtca gctcggccgc ttcttgttcg gtaaaactta cgcctggaat ctgcgatagc
     5041 agcggcagaa tcgtcacgcc ggagtgcccg ccaatcaccg gaacttcaac ttccgttggc
     5101 agcttacctt tcagctctgc gacaaaggta ttagagcgga tgatatccag cgtggtaacg
     5161 ccaaacagtt tgtttttgtc gtatacgcct gcttttttca acacttccgc cgcaatcgca
     5221 acggtggtgt tcaccgggtt ggtgataatg cccacgcacg ctttcgggca ggttttagcg
     5281 atctgctgca ccaggttttt cacgatgccg gcgttaacgt taaacaggtc ggaacggtcc
     5341 atacccggct tacgcgccac acccgcagaa atcagtacta cgtcagcgcc ttcaagcgcc
     5401 ggggttgcgt cttcaccgga gaaacctttg atttttacag cggtggggat gtggcttaaa
     5461 tcaacggcca caccgggagt cactggagcg atgtcgtaca gggagagttc tgaacctgaa
     5521 ggcagttggt tttttaaaag taatgccagc gcctgaccga taccaccagc agcgccgagg
     5581 actgcgactt tcatcctaaa ctccttatta tatgattagc taagtgtcta ttgctccgcg
     5641 gcggcgacct taattcacaa attcaatgat tacaatcctc actcatcaag aatgcggagt
     5701 cgcgcaattt tggcttttat gcatttaatt tgcgtaatcc ggatcggctg caaccagaga
     5761 gcaacgttct acaggtggtg acaatatacc ctactaccct ctcaaaacaa catcattttg
     5821 ataacaatta atttactttt aatcttattt gcgaggcgtg acacaggcat gtttcttgat
     5881 tacgaaattt gataaaattc cgctctttca taacattatt tcagccttaa acaaggcaga
     5941 ctgtttgcat aaaaattcat ctgtatgcac aataatgttg tttctaccgc catattacgg
     6001 gtgacttatg cgaagctcgg ctaaacaaga agaactagta agagcgttta aagcgctcct
     6061 caaagaagaa aaattcagct cacagggcga aatcgtcctc gcgttgcagg atcagggctt
     6121 tgaaaatatc aatcagtcca aggtctcgcg catgttgact aagttcggcg cagtgcgtac
     6181 acgtaacgca aaaatggaaa tggtgtactg tcttccggct gaactgggcg tcccaacaac
     6241 atccagtccg ttgaaaaatc tggtgctgga tatcgactat aacgatgctg tcgtggtgat
     6301 tcataccagc cccggcgcgg cacaactcat tgcgcgcctg ctggattcac tggggaaagc
     6361 agaaggtatt ctcggcacga ttgccggcga cgatactatc ttcactacgc ctgccagcgg
     6421 cttttccgta agagatctgt acgaagccat tctggaactt tttgaacaag agctttagtc
     6481 ccacttcctc cgtcgtcgta cggcggaggc atctttttgc cctctcccct cgccgctttc
     6541 ctgtacggct atcatttggc aaatcatgcc cttaaacatt caccacatga atgaaaaatc
     6601 aaaaaaacgc acaaaatgtc aattttttta accagttgat tttcttttat ttttcaaacg
     6661 acagcggcga a
//
LOCUS       DAJVKX010000182         6666 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.182, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000182 DAJVKX010000000
VERSION     DAJVKX010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6666
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.182"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            111..1247
                     /locus_tag="OPY25_004151"
     CDS             111..1247
                     /locus_tag="OPY25_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HCS0929613.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLFGKVDGLHYF
                     SDDKGSDGDQTYMRIGFKGETQVNDQLTGYGQWEYQIQGNQTEGSNDSWTRVAFAGLK
                     FADAGSFDYGRNYGVTYDVTSWTDVLPEFGGDTYGADNFMQQRGNGYATYRNTDFFGL
                     VDGLDFALQYQGKNGSVSGENTNGRSLLNQNGDGYGGSLTYAIGEGFSVGGAITTSKR
                     TADQNNTANARLYGNGDRATVYTGGLKYDANNIYLAAQYSQTYNATRFGTSNGSNPST
                     SYGFANKAQNFEVVAQYQFDFGLRPSVAYLQSKGKDISNGYGASYGDQDIVKYVDVGA
                     TYYFNKNMSTYVDYKINLLDKNDFTRDAGINTDDIVALGLVYQF"
     gene            1362..2414
                     /gene="apbE"
                     /locus_tag="OPY25_004152"
     CDS             1362..2414
                     /gene="apbE"
                     /locus_tag="OPY25_004152"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HCS0929614.1"
                     /translation="MKMTFCRAVCLAAAFLLMGCDEAPETTTASPAAQVLEGKTMGTL
                     WRVSVVGIDAKRAAELQTKIQTQLDADDWLLSTYKNDSALMRFNHSRSLAPWPVSEAM
                     ADIVTSALRIGAKTDGAMDITVGPLVNLWGFGPDRQPLHIPTPAQIDAAKAKTGLQHL
                     QVIDRAGHQFLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGIARYLVSVGGALSSRG
                     MNAQGLPWRVAIQKPTDRENAVQAIVDINGHGISTSGSYRNYYELDGKRVSHVIDPQT
                     GRPIEHNLVSVTVIAPTALEADGWDTGLMVLGTQKAQEVVRREGLAVFMIMKEGEGFK
                     TWMSPQFKTFLVSDKN"
     gene            2495..3556
                     /gene="ada"
                     /locus_tag="OPY25_004153"
     CDS             2495..3556
                     /gene="ada"
                     /locus_tag="OPY25_004153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HCS0929615.1"
                     /translation="MMKKALLTDDECWLRVQARDASADGRFVFAVRTTGVFCRPSCRS
                     KRALRKNVRFFANAQQALDAGFRPCKRCQPDNARAQQRRLDKIACACRLLEQETPVTL
                     ASLAQAVAMSPFHLHRLFKASTGMTPKGWQQAWRARRLREALAKGEPITAAIYRAGFP
                     DSSSYYRHADQTLGMTAKQFRKGGDNVSVRYALTDWVYGRCLVAESGRGICAILPGDS
                     DDALLAELHTLFPAARHEPADAPFQQRVRQVVAAINTRDVLLSLPLDIQGTAFQQQVW
                     QALCAIPCGETVSYQQLAATIGKPTAVRAVASACGANKLAMVIPCHRVVRRDGALSGY
                     RWGVRRKAQLLKREAQKEE"
     gene            3559..4209
                     /gene="alkB"
                     /locus_tag="OPY25_004154"
     CDS             3559..4209
                     /gene="alkB"
                     /locus_tag="OPY25_004154"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HCS0929616.1"
                     /translation="MLDLFADEAPWQEPLAPGAVVLRRFAFRAAQSLLDDIGFVASQS
                     PFRQMVTPGGYTMSVAMTNCGALGWTTDGHGYCYAVRDPLTDKPWPALPLSFASVCRQ
                     AAIAAGYASFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGVPAVFQFGGLR
                     RSDPLQRILLEHGDIVVWGGESRLFYHGIQPLKAGFHPMTGEFRYNLTFRQAAEKE"
     gene            4285..5928
                     /locus_tag="OPY25_004155"
     CDS             4285..5928
                     /locus_tag="OPY25_004155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug ABC transporter permease/ATP-binding
                     protein"
                     /protein_id="HCS0929617.1"
                     /translation="MELLILVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETV
                     DTTVMVLPEFLGLLLLLMVVTLGSQLALTALGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDIRNITIAFVRLPELVQGIVLTVGSAAYLAMLSTKMLLVTAIWMAVT
                     IWGGFVLVARVYQHMATLRETEDKLYNDYQTVLEGRKELTLNRERAEQIFQQCYTPDA
                     KEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPYKPDFPQPKAFPDWKTLELRNVVFHYQD
                     NAFSVGPINLTIHRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGTILLDGQPVAAGQP
                     EDYRKLFSAVFTDVWLFDRLLGPQGKPANPALVEKWLEHLKMTHKLELNDGCILNLKL
                     SKGQKKRIALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLTELTGDERDAASRDAVARTA"
     gene            complement(6137..6631)
                     /gene="eco"
                     /locus_tag="OPY25_004156"
     CDS             complement(6137..6631)
                     /gene="eco"
                     /locus_tag="OPY25_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HCS0929618.1"
                     /translation="MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKR
                     QVITLTPQQDESTLKVELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSP
                     VSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQN
                     AIAR"
BASE COUNT         1420 a         1740 c         1970 g         1536 t
ORIGIN      
        1 gattattctg tatttttgcg gagaatggac ttgccgactg gttaatgagg gttaaccagt
       61 aagcagtggc ataaaaaagc aataaaggca tataacagag ggttaataac atgaaagtta
      121 aagtactgtc cctcctggta ccagctctgc tggtggcggg cgcagcgaat gcggctgaaa
      181 tttataataa agacggcaac aaattagacc tgtttggtaa agttgatggc ctgcactact
      241 tctctgacga caaaggcagc gacggcgacc agacctacat gcgtatcggc ttcaaaggcg
      301 aaacgcaggt taacgatcag ctgaccggtt atggccagtg ggaatatcag attcagggca
      361 accagactga aggcagcaac gactcctgga cgcgtgtggc gtttgcgggt ctgaaattcg
      421 ctgacgcagg ttccttcgat tatggtcgta actacggcgt aacctatgac gtgacctcct
      481 ggaccgacgt tctgccggag ttcggcggcg acacctacgg cgctgacaac tttatgcagc
      541 agcgtggtaa cggctatgct acctaccgta acaccgactt cttcggtctg gtggatggtc
      601 tggacttcgc gttgcagtat cagggcaaaa acggcagcgt gagcggtgaa aacaccaacg
      661 gtcgcagcct gctgaaccag aacggcgacg gttacggcgg atcgctgact tatgcaatcg
      721 gcgaaggctt ctctgtcggt ggcgctatca ccacgtctaa acgtactgcc gatcagaaca
      781 acaccgctaa cgctcgcctg tatggtaacg gcgatcgcgc cacggtttac accggcggcc
      841 tgaaatacga tgcgaacaac atctatctgg cagcgcagta ttctcagacc tataacgcaa
      901 cccgttttgg tacctctaac ggcagcaacc cgtccacctc ttacggtttt gccaacaaag
      961 cgcagaactt tgaagtggtt gctcagtacc agttcgactt tggtctgcgt ccgtctgtgg
     1021 cttacctgca gtctaaaggt aaggacatca gcaacggcta cggcgccagc tatggcgacc
     1081 aggacatcgt aaaatacgtt gatgtcggcg cgacttacta cttcaacaaa aacatgtcca
     1141 cctatgttga ttacaaaatc aacctgctgg ataaaaacga ctttacccgc gatgcgggca
     1201 tcaacaccga cgacatcgta gcgctgggtc tggtttacca gttctaatca gcaaaagatg
     1261 ttgctaaagg gcctgcgggc ccttttttca tgccttattc cggcgtacaa atacgacgtt
     1321 ttgatatacg cttgcgtcca ttcgaatgag gataaacagc gatgaaaatg actttttgcc
     1381 gggccgtgtg tctggcagcg gcttttttac ttatgggctg cgatgaggct cccgaaacga
     1441 caacagcgtc acctgccgct caggtgctgg aaggtaaaac gatgggaacc ctctggcggg
     1501 tgagcgtggt tggtatcgat gcgaaacgtg ccgcagagtt acagactaaa atccagactc
     1561 agcttgatgc tgatgattgg ttgctttcta cctataaaaa tgactccgcg ctgatgcgtt
     1621 ttaaccattc acgcagtctt gcgccctggc cggtcagcga agccatggcg gatatcgtga
     1681 cctcggcgct gcgtattggc gcgaagacgg acggcgcgat ggatatcacc gtgggcccgc
     1741 tggtcaatct gtgggggttt ggaccggatc ggcagccgct gcatatccca acaccagcac
     1801 aaatcgatgc ggcaaaagcg aaaacaggcc tgcaacattt gcaggttatc gacagggctg
     1861 gacatcagtt tttgcaaaaa gatctgccgg atctttatgt tgatctctcc acggtcgggg
     1921 agggctatgc ggcggatcat ctggcgcgtc tgatggagca ggagggcatt gcgcgttatc
     1981 tggtctcggt gggcggcgca ttaagcagtc gcgggatgaa tgcgcagggg ctgccgtggc
     2041 gcgtcgcgat tcagaagccg accgaccggg aaaacgcggt gcaggcgatt gtggatatca
     2101 acgggcatgg catcagcacc tccggcagct accgtaacta ttacgagctg gatggcaagc
     2161 gcgtatcgca cgttatcgat ccgcaaacgg ggcgccccat tgaacacaat ctggtatcgg
     2221 ttacggtcat cgcgccaacg gcgctggaag cggacggctg ggacaccggc ctgatggtgc
     2281 tcggtacgca aaaggcgcaa gaggtcgtgc ggcgggaagg gctggcggtc tttatgatca
     2341 tgaaagaagg tgaaggcttt aaaacctgga tgtcgccgca gttcaaaaca ttcctggtga
     2401 gcgataagaa ttaaaacgca agattacggg tttttgtggg cggatttacg gacacactgc
     2461 atgtaagcaa gcactatgct taatgaagga gtctatgatg aaaaaagcgt tacttaccga
     2521 tgatgaatgc tggctgcggg tgcaggcgcg cgatgccagc gcggatgggc gtttcgtttt
     2581 tgcagtgcga accactggcg ttttttgccg cccttcttgt cgctcgaagc gggcgttacg
     2641 taaaaatgtt cgcttttttg ccaacgcgca gcaggcgctg gacgccggtt ttcgcccctg
     2701 caagcgctgt cagccggata atgcgcgcgc gcagcaacgg cggttggata agattgcctg
     2761 cgcctgccgt ttacttgagc aggagacgcc ggtaacgctg gcgtctctgg cgcaggcggt
     2821 ggcaatgagt ccgtttcatc tgcaccgttt gtttaaagcg agcaccggaa tgacgccgaa
     2881 agggtggcag caggcgtggc gcgcccggcg gctgcgtgag gcgttggcga aaggagagcc
     2941 gatcacggcg gctatttacc gcgccggctt cccggatagc agtagctact atcgtcatgc
     3001 cgaccagacg ctgggcatga cggcaaaaca gtttcgcaaa ggcggcgata atgtctccgt
     3061 tcgctatgcg ctgacggact gggtttacgg acggtgcctg gtggcggaga gcgggcgggg
     3121 gatttgcgcg attctccccg gtgatagcga cgatgcgcta ctggccgaat tacacaccct
     3181 tttcccggcg gcccgccacg aacctgctga cgcgcctttt cagcaacggg tgcggcaggt
     3241 tgtcgcggct atcaacacac gcgatgtgct gctctcgttg ccgctggata tccagggaac
     3301 cgcgtttcaa cagcaggtct ggcaggcgtt atgcgcgatt ccctgcggcg aaaccgtaag
     3361 ctatcaacag cttgccgcga ctatcggcaa acccacggca gtacgcgcgg tcgccagcgc
     3421 gtgcggcgcg aataaactgg cgatggtgat cccgtgtcat cgggtcgtgc gtcgcgatgg
     3481 cgcgctctcc ggttatcgtt ggggcgtgcg tcgaaaagcg cagctattaa agcgagaagc
     3541 gcaaaaagag gagtagcaat gctggatctg tttgctgatg aagcgccctg gcaagagccc
     3601 ctggcgcctg gcgcggtggt gttgcgccgc tttgcgtttc gcgcggcgca gtcgctatta
     3661 gacgatatcg gatttgtcgc cagtcagtca ccgtttcgtc agatggtgac gccgggcggc
     3721 tacactatgt cggtggcgat gaccaactgc ggcgcgttag ggtggaccac cgatggtcac
     3781 ggttattgtt atgccgtgcg cgatccgttg accgataaac cctggcctgc gctgccgtta
     3841 tcgtttgcca gcgtatgtcg tcaggcggca atcgcggcag ggtatgctag cttccaaccg
     3901 gacgcctgcc tgatcaatcg ctacgcgcct ggcgcaaaac tgtcgctgca tcaggataaa
     3961 gacgagccgg atctgcgcgc gcctatcgtc tcagtttcgt tgggggtgcc ggcggttttt
     4021 cagtttggcg gcctgcgtcg cagcgatccg ctccagcgga tcttactgga gcatggcgat
     4081 atcgtggtct ggggcggcga gtcccgcctg ttttatcacg gtatccagcc gcttaaagcg
     4141 ggctttcatc ccatgaccgg tgaatttcgt tacaatctca ccttccgtca ggcggctgaa
     4201 aaagaataaa aataagaatt attattgctg tgcaggtaga gttagttaaa ctgcgggctg
     4261 ttattatcgg tccgggttgt atgcatggaa cttcttattc ttgtctggcg gcagtaccgc
     4321 tggccattta ttagcgtgat ggcgctgagc ctcgccagcg cggcgctggg gattggcctg
     4381 atcgcgttta tcaatcagcg cctgattgaa acggtggaca ccaccgtcat ggtgctgccg
     4441 gaatttctcg gtctgctcct gttgctaatg gttgtcacat taggttccca actggcgctc
     4501 accgctctgg gacaccattt cgtttaccgc ctgcgcagcg aatttatcaa gcgcattctg
     4561 gatacgcacg ttgaacgcat tgagcaactg ggcagcgcct ctttactggc cggtctgacc
     4621 agcgatattc gcaatattac tatcgccttt gtgcgtctgc ctgagctggt gcagggcatt
     4681 gtcctcaccg tcggctcggc ggcgtatctg gcgatgctat cgacaaaaat gctgctggtt
     4741 acggctatct ggatggcggt cactatctgg ggcggattcg tgctggtggc gcgggtttac
     4801 cagcatatgg cgaccctgcg cgagaccgaa gataagctgt acaacgacta tcagacggtg
     4861 ctggagggac gcaaagagct gacgctaaac cgcgagcgtg cggagcagat ttttcagcaa
     4921 tgctataccc cggacgccaa agagtaccgt catcacatta tccgtgccga tacttttcac
     4981 ctgagcgccg tcaactggtc gaatatcatg atgctggggg cgataggcct ggtcttctgg
     5041 atggcgaata gtctcggctg ggcggatacc aacgtcgcgg cgacctattc actgacgttg
     5101 ctgttcctgc gcacgccgct gctgtctgcg gtgggggcgt tgccaacgct actgaccgcc
     5161 caggtggcgt ttaataaact gaataaattc gcgctcgccc cgtataagcc tgattttcca
     5221 cagccgaaag cctttcccga ctggaagacg ctggagctgc gcaacgtggt ttttcactat
     5281 caggataacg cgttttccgt ggggcccatc aacctgacga ttcaccgcgg cgaactgctg
     5341 tttttaattg gcggcaacgg tagcgggaaa tcgacgctgg ccatgttatt gaccggttta
     5401 taccagccgc aatcgggaac gattttactt gacggtcaac ctgttgccgc cgggcagccg
     5461 gaagattatc gcaaactgtt ttctgcggtg ttcaccgatg tgtggttatt cgaccgcctg
     5521 ctggggccgc aggggaaacc cgccaatccc gcgctggtcg aaaagtggct tgagcacctg
     5581 aaaatgacgc acaagctgga gctaaacgat gggtgcatct tgaatcttaa actgtcgaaa
     5641 gggcaaaaaa agcgcattgc gctgctgctg gcgctggcgg aagagcgcga tattattttg
     5701 ctggatgagt gggccgccga tcaggacccg catttccgcc gggaatttta tcaggtactg
     5761 ttgccgttaa tgcaggaaat gggcaaaacc attttcgcca tcagccatga tgatcactat
     5821 tttattcacg ccgatcgcct gcttgaaatg cgtaacgggc agttaaccga actcaccggc
     5881 gacgaacgtg acgccgcttc gcgtgatgcg gttgcgcgta ctgcgtaatg gactatggcg
     5941 ccggataaac tgcctgatgg cagccctacg tccgcacgcg ggtaggcctg ataagatgcc
     6001 acgcgtcgcc accaggcatc ggggtatttt ttgcggcggg cgagcgggtt tccagacgtg
     6061 ttttaaaaag aaccccggag cgctgcgtga gtcggcgtgt tcagatgccc ggtaagtgtg
     6121 accgggcagc gtaacattat cgcgcgatgg cattctgtac gttagcgtcc gctttccaga
     6181 tgcggtattt cacgtccaca ttcgccgggg tatacaccac gatcggcagc ttgctgttgt
     6241 agcgcagcat cccgtcttca cccagccagg cggtgacgaa tttttgctct ttcttacctt
     6301 cagggcaggc catcatggtt gataccggag aggtgacgtt atcaaagaca taatagtcgt
     6361 agccccagcc ttccagcgtt tttgtttcca gcgtgccgcc gaggcgatgc tggttacaat
     6421 ccacattcag cgtttgacca atcaacagtt ccactttgag ggtagattca tcctgctgag
     6481 gggtaagggt tatcacttgc cgcttcattc ctttctccgc ctgcggatag ggggcgattt
     6541 tttccagcgg ctgggcggta tcgccattgt tagcccaggc agaggcgctg gcgagggcgg
     6601 cgaagacgac ggcagggaca aacatcttca tttgattgtt cacagtattt cctttctgct
     6661 gttttc
//
LOCUS       DAJVKX010000183         6631 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.183, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000183 DAJVKX010000000
VERSION     DAJVKX010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6631
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.183"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            519..1076
                     /gene="pagC"
                     /locus_tag="OPY25_004157"
     CDS             519..1076
                     /gene="pagC"
                     /locus_tag="OPY25_004157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence membrane protein PagC"
                     /protein_id="HCS0929619.1"
                     /translation="MKNIILSTLVITTSVLVVNVAQADTNAFSVGYAQSKVQDFKNIR
                     GVNVKYRYEDDSPVSFISSLSYLYGDSQDSGSIESEGIHYHDKFEVKYGSLMVGPAYR
                     LSDNFSLYALAGVGTVKATFKEHATQDGDSFSNKISSRKTGFAWGAGVQMNPLENIVV
                     DVGYEGSNISSTKINGFNVGIGYRF"
     gene            1481..1557
                     /locus_tag="OPY25_004158"
     tRNA            1481..1557
                     /locus_tag="OPY25_004158"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1515..1517,aa:Arg,seq:cct)
     gene            complement(2310..2654)
                     /locus_tag="OPY25_004159"
     CDS             complement(2310..2654)
                     /locus_tag="OPY25_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-type lysozyme inhibitor"
                     /protein_id="HCS0929620.1"
                     /translation="MMKRKLIPFTLFLAALSASTTSIAASQEISKSIYTCNDNQVMEV
                     IYVNTEAGNAYAIISQVNEMIPMRLMKMASGANYEAIDKNYTYKLYTKGKTAKLVEGD
                     DKPVLSNCSLAN"
     gene            3032..3157
                     /locus_tag="OPY25_004160"
     CDS             3032..3157
                     /locus_tag="OPY25_004160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0929621.1"
                     /translation="MKKWLIGGILIASFLTGCLMWHNIDKWFNKDIEVFYAGDDN"
     gene            3357..3584
                     /locus_tag="OPY25_004161"
     CDS             3357..3584
                     /locus_tag="OPY25_004161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929622.1"
                     /translation="MLLVGLPPVAEKDNDDVTVAETDEYDDREFYFWRPYFLPKGRPK
                     AALGLIMEKGVGHCHNQPVYTNVIDNHYQLW"
     gene            3782..4249
                     /locus_tag="OPY25_004162"
     CDS             3782..4249
                     /locus_tag="OPY25_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20 family protein"
                     /protein_id="HCS0929623.1"
                     /translation="MALRTLSALPVFADSLFSDRFNRIDRLFSQLTGDTPVAATPAYD
                     LQKRDANNYLLTVSVPGWKEEELEIETVGGNLNITGKHTEETVEDQTHWIYRGIRKAD
                     FQLSFSLPEHAKVNNAKLEQGLLLVEIYQEIPESEKPKKIAIESKPKAIEHKS"
     gene            4588..5631
                     /locus_tag="OPY25_004163"
     CDS             4588..5631
                     /locus_tag="OPY25_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HCS0929624.1"
                     /translation="MKLALVNRQVILPESGTESFQCHASTLVRLPCGTLVAAWFAGLC
                     EGSEDTAIWLSRYEHNIWTTPQRVAAREGEAHWNPVLFYPSDKLWLFYKVGSGVHVWK
                     TWFITSSDRGFTWSTPAPLVNDDILPRGPVKNKLLLASNGAWIAPGSIESPERWRAFV
                     DRSSDEGKHWNISFVPLEPDNAISGTNVALWDGVKKGMLWECCLENLLRWDGVIQPTL
                     WESSPGHIHMLLRSTRGAIFRSDSIDYGATWSVARATFLPNNNSGIDLVSMQDGTLIL
                     ALNPVNGNWGKRYPLSLIASQDNGESWLPLLDLESDHGEYSYPAIISKGGVVHITYTW
                     NRKNIVYCRLQTV"
     gene            complement(5714..6244)
                     /locus_tag="OPY25_004164"
     CDS             complement(5714..6244)
                     /locus_tag="OPY25_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HCS0929625.1"
                     /translation="MAHFSRLQITLHWLTLLLTGIAYAAIELRGWAPKGSSVYLFMKD
                     MHYDMGVLVWALMFLRLYLKHKYPDPVITPPPPHWQHVAAKLMHIALYLTFLALPLLG
                     VAMMASGGKSWSFFGFTVPVFLTPDSTLKSDIKRIHEMLANIGYFLIAMHAAAALFHH
                     YIQKDDTFSRMLPGKS"
     gene            complement(6393..6623)
                     /locus_tag="OPY25_004165"
     CDS             complement(6393..6623)
                     /locus_tag="OPY25_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRL-like family protein"
                     /protein_id="HCS0929626.1"
                     /translation="MGLYTDVKGPITATSLPATKTGKACAQTVLGIVNTGDASIDSAK
                     KAGDISLVSSVDYETTGSYPFYGKTCVVVRGQ"
BASE COUNT         1835 a         1343 c         1578 g         1875 t
ORIGIN      
        1 cgggaataaa gcatgctgaa catcatggtg aataggatta cggtgccagc gatggcatgt
       61 aacggcattt cgtctggagc gtcacgtgag gactgtgaag cacaatgcga tatgttctgg
      121 ttatatggcg agtttgctta atgacatttt tttagccgat cagcgtcagg cttcttaatg
      181 tggttgtgat atttttcttt aaatatcaaa agtttgtatg acgtgtttgt tgttttatag
      241 tggctaaaca ctttatggtt tctgttaaat atatatgcgt gagaaaaatt agcattcaaa
      301 tctataaaag tgagatgaca ttgtagaacc ggttacctta atgagcgata gagcgcttcg
      361 gtagtaaaaa tatctttcag gaagtaaacg catcaggagc gatagcggtg aattattcgt
      421 ggtttgtcga ttcggcatag tggcgataac tgaatgccgg atcggtactg caggtgttta
      481 aacacaccgt aaataataag tagtattaag gagttgttat gaaaaatatt attttatcca
      541 ctttagttat tactacaagc gttttggttg taaatgttgc acaggccgat actaacgcct
      601 tttccgtggg gtatgcacaa agtaaagttc aggatttcaa aaatatccga ggggtaaatg
      661 tgaaataccg ttatgaggat gactctccgg taagttttat ttcctcgcta agttacttat
      721 atggagacag ccaggattcc gggtctattg agtctgaagg tatccattac catgacaagt
      781 ttgaggtgaa atatggttct ttaatggttg ggccagccta tcgattgtct gacaattttt
      841 cgttatacgc gctggcaggt gtcggcacgg taaaggcgac atttaaagaa catgccactc
      901 aggatggcga ttctttttct aacaaaattt cctcaaggaa aacgggattt gcctggggcg
      961 cgggtgtaca gatgaatccg ctggagaata tcgtcgtcga tgttgggtat gaaggaagca
     1021 acatctcctc tacaaaaata aacggcttca acgtcggaat tggataccgt ttctgaaaag
     1081 cataagctat gcggaaggtt cgccttccgc accgccagtt acaaaacagg gcttctttac
     1141 cagtaacacg tacctgcctg tcttttctct cttcgtcata ctctcttcgt catagtgacg
     1201 ctgtacataa tatctcacca gcataagcac agataaagga ttgtggtaag caatcaaggt
     1261 tgctcaggta ggtgataagc aggaaggaaa atctggtgta aataacgcta gatctcacag
     1321 gattcactct gaaaaatttt cctggaatta atcacaatgt catcaagatt ttgtgatcgc
     1381 cttcgcatat tgtacctgcc gttgaacgac tactaaaaag tagcaaggta tgtattttat
     1441 ctaggagagc accttttttg cgcctggcag aagtccccag ccgccactag ctcagctgga
     1501 tagagcatca acctcctaag ttgatggtgc gaggttcgag gcctcggtgg cggtccaatg
     1561 tggttatcgt ataatgttat tacctcagtg tcaggctgat gatgtgggtt cgactcccac
     1621 tgaccacttc agttttgaat aagtattgtc ttgcaatcct gttacagaat aatttcattt
     1681 attacgtgac aagatagtca tttataaaaa atgcacaaaa atgttattgt cttttattac
     1741 ttgtgagttg tagatttttc ttatgcggtg aatccccctt tgcggcgggg cgtccagtca
     1801 aatagttaat gttcctcgcg aaccatattg actgtggtat ggtccaccgg gaggcacccg
     1861 gcaccgcaat tttttataaa atgaaattca caccctatgg ttcagagctg tgtttttaca
     1921 tcaggtgggc aagcataatg caggttaact tgaaagatac gagcaataac agaaaccagt
     1981 gatttcgttt atggcctggg gatttaaccg cgccagagcg tatgcaagac cctggcgcgg
     2041 ttggccggtg atcgttcaat aatgcgaata tgaatggtta ccagccgctg cgaattctac
     2101 ctgggtcact taataaagca aaacatttaa acactcaaca acgacaattc agacagttcg
     2161 aacttttctt taaaaatagg attaaccatg tttaaaagtg gttactaatt agccattatc
     2221 ctacggtagt gattcacata ttctttaacg ttacgttaca ggaaggttga agtggaaatg
     2281 cctgatgagc cttcaggcat ttctgaaggt tagttagcta aggaacagtt actgagaaca
     2341 ggtttatcat caccttccac cagtttagcc gttttgcctt tggtataaag tttgtaagta
     2401 taatttttgt ctatggcttc gtaatttgct ccggaggcca ttttcattaa ccgcatcggg
     2461 atcatctcgt ttacctgact gataatcgca taggcgtttc cagcctcggt gttgacgtaa
     2521 atcacctcca taacctggtt atcattacag gtgtatatag atttagaaat ctcctgcgaa
     2581 gctgctatag aggtggtact ggcgctaagc gcagcgagaa agagggtaaa tgggatcaat
     2641 ttacgtttca tcattagtat cctttgtgta taaaattgtc gttaattccc tgaagagcgg
     2701 gagataaagc ggcatcaata cgatgaatgc tgtagtattc ctgtttactg acgaaaagtg
     2761 cgccagaaaa gcgtattata atttatccat cactgacata tgtgatgagt agacaaatct
     2821 taaaatcata aactatagac tgcaaatcat tatggcgcga tggaaaatga ttgtcaccac
     2881 tgctcaatac tatggcataa aaaccgaaga aaacggtact gttcactgtc tcgtttcata
     2941 cggtatctgt cagtgaaact atttcttcaa atgatggtct ttttattatc gatcagataa
     3001 tggcatcaac aggggttatt taggagtata tgtgaaaaag tggcttatag gagggatatt
     3061 gatcgcaagt tttctgaccg gttgtctgat gtggcacaac attgataaat ggtttaataa
     3121 agatatcgaa gttttctacg ccggagacga taactaaaac tcctgtcagt tggcaacggg
     3181 tgtcatatct tcaggtatgg cgcccggagc agccgggcgc aaattgtagg tgtataaaag
     3241 tcatttcatt aaaattttag cgacaacatg gacagtcact accgcgtgct aacggccctc
     3301 tgaagtcaca agatgaataa gccagttttt tgtttcagcg gtgactgaaa catattttgc
     3361 tcctggtggg cttaccgcca gttgctgaaa aagacaacga tgatgtaact gttgcagaga
     3421 ctgacgaata cgacgaccgt gagttttatt tttggcgacc atatttcctc ccaaaaggcc
     3481 gcccgaaggc ggcgctgggt ttgataatgg agaagggcgt tggtcactgc cataaccaac
     3541 ctgtatacac taatgtaatt gataatcatt atcaattgtg gtgatgaaga aaaattgtaa
     3601 agatgaaggg acagcggaaa tggcaatgaa cgggatgaga tttttcgtta accacttaaa
     3661 ttcgtgacta aaaaaagtct tttataggct tgaaaatgtt ttttccgtcc ctatgtagtc
     3721 agtggacaag caatgcttgc cttgatgttg aacttttgaa tagtgattca ggaggttaat
     3781 gatggcactc agaaccttgt cagcacttcc cgtgtttgct gattctcttt tctctgaccg
     3841 tttcaaccgt attgatagac ttttcagtca attaacagga gatacgccag tcgctgcgac
     3901 gccagcttac gatctgcaaa agcgcgatgc gaataactat ctgcttaccg tgagcgttcc
     3961 tggctggaaa gaggaagagc ttgaaattga aacggttggc ggcaacctga atattacggg
     4021 taaacacact gaagagacgg tagaggatca gacgcactgg atttatcgtg gtattcgtaa
     4081 ggcagatttc cagttgagtt tttctttgcc tgaacatgct aaggtgaata atgcaaaact
     4141 ggaacagggc ctcttgttgg tagagattta ccaggaaatc cctgaaagcg agaaaccgaa
     4201 aaaaattgcc atagaaagca aaccaaaggc gattgaacat aaatcataaa agcattaatg
     4261 gaggcccgtt tagacgggcc ttcattgtct gtagcgaaaa gtatcccgtc atgcttgtag
     4321 gcacagatcg ctaaatatta tagccctgac ctctatatta tcccgtgcca ctgacctcgt
     4381 cgccattgga cggcggtaag ttggaattat ccgcgaggtc agtccaattt ttgtccactc
     4441 tcgacattct gcctgttatg ggcgcgatac ctgaacataa attcgtatag cggttgatcg
     4501 ttttcaccgc gttgatgcta tttctgctaa cactactttc atacgtaaaa aagctgatgc
     4561 tttttacctt atttaataga ggcaggtatg aaattagcgc tcgtcaatcg acaggtcatt
     4621 ttaccggaaa gcggaaccga gtccttccag tgccatgcct ctacgcttgt tcgcctaccg
     4681 tgcggtacgc tcgtggccgc atggttcgcg gggttgtgcg aaggaagcga agatacagcc
     4741 atctggctat ctcgctatga acataatatc tggacaacac cgcagcgagt ggcggcacgc
     4801 gagggggaag cgcactggaa tccggtgtta ttttacccgt cggataaatt gtggttattt
     4861 tataaagtag gcagcggcgt acacgtgtgg aaaacctggt ttatcacctc cagcgatcga
     4921 ggatttacct ggagtacgcc agctccgttg gttaacgatg atattttgcc gcgcggtccc
     4981 gtaaaaaata aactcctgct ggcatcaaat ggcgcctgga ttgcgccagg gtcgattgaa
     5041 agtcctgaac ggtggagggc atttgtggat cgatcctctg acgaaggaaa acactggaat
     5101 atctcttttg ttccgctgga gcctgataac gctatttccg ggacaaacgt agcgttgtgg
     5161 gatggtgtaa aaaaggggat gttgtgggaa tgttgtctgg aaaacctcct gcgctgggat
     5221 ggcgttattc agcctacgct gtgggagtct tctccggggc atatccatat gttgttacga
     5281 agcacacgcg gggcaatttt tcgcagtgat tcaatcgact atggcgctac ctggtctgtt
     5341 gcccgcgcga catttttacc gaataataat agtggtatcg atctggttag tatgcaggac
     5401 ggtacgctga ttcttgcgtt aaatccggtc aacggcaact ggggaaagcg ctatccgctt
     5461 tcactgattg cttcccagga taatggcgaa tcatggctac cgctactgga cctggaaagt
     5521 gaccacggtg agtattctta tcccgctatt attagcaagg gcggcgtcgt acatatcacc
     5581 tacacgtgga accggaaaaa tatcgtatat tgtcgattac aaacggtata aggcgctatc
     5641 agtcgaaacc gatagcgctg gaataataat gccttgcccg gcgtgctctc tcacgtcggg
     5701 atggccgaaa tagtcatgat ttaccgggta acatccttga aaatgtatcg tctttttgta
     5761 tgtaatggtg aaacaacgcc gctgctgcat gcatggcaat caggaaatag ccgatattgg
     5821 ccagcatttc atgaatacgc tttatatccg attttagggt gctatctggc gtcaaaaata
     5881 ccggtacagt aaaaccaaaa aagctccagc ttttcccgcc tgatgccatc atcgcgacgc
     5941 ccagcagcgg taaggcgaga aaagtgagat aaagcgcgat atgcattaat ttagcggcta
     6001 cgtgctgcca gtgaggaggg ggaggcgtaa tgaccggatc cgggtatttg tgtttaagat
     6061 ataaccgtaa aaacatcagc gcccagacca gaacgcccat gtcatagtgc atgtctttca
     6121 taaataggta aacgctggag ccttttggcg cccacccccg taactcaata gccgcatatg
     6181 ctatgcctgt caggagcagt gttaaccagt gaagcgttat ttgcagtctt gagaaatgtg
     6241 ccattattat tatcctttat taacaactgc ttgtagggta tgcgtaaaat cttaacagaa
     6301 ccttaaagcg ggggctgagt cgcaaggaac agacagagat agcggcacgt aaaatgggat
     6361 aaaaagccgg cggcatcgcc ggcttactgt tgttattgtc ctcttacgac aacacaggtt
     6421 ttaccataaa acggatatga gcctgtagtt tcataatcaa cactcgacac taaagaaata
     6481 tcgcccgctt ttttcgctga atcaatagat gcgtcgccgg tatttacaat acccaatacc
     6541 gtttgcgcac acgctttacc ggttttggtt gccgggagac tcgtggcagt aattggccct
     6601 ttaacatccg tatataagcc aatccctgtc g
//
LOCUS       DAJVKX010000184         6517 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.184, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000184 DAJVKX010000000
VERSION     DAJVKX010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6517
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.184"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(156..1553)
                     /locus_tag="OPY25_004166"
     CDS             complement(156..1553)
                     /locus_tag="OPY25_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HCS0929627.1"
                     /translation="MNNNDLVAKLWKLCDNLRDGGVSYQNYANELASLLFLKMCKETG
                     QEADYLPEGYRWDDLKSRIDQEQLQFYRKMLVHLGEDKKKLVQAVFHNVCTTITEPKQ
                     ITELVSNMDSLDWYSGTRGKSRDDFGDMYEGLLQKNANETKSGAGQYFTPRPLIKTII
                     HLLKPQPREVVQDPAAGTAGFLIEADRYVKSQTNDLDDLDGDTQDFQIHRAFIGLELV
                     PGTRRLALMNCLLHDIEGNLDHGGAIRLGNTLGSDGENLPQADIVATNPPFGSAAGTN
                     ITRTFVHPTSNKQLCFMQHIIETLRPGGRAAVVVPDNVLFDRVGLEIRRDLMDKCHLH
                     TILRLPTGIFYAQGVKTNVLFFTKGTVANPTQDKDCTDDVWVYDLRTNMPRFGKRTPF
                     TEQYLQPFETVYGEDPHGLSPRAEGEWSFNAEETEVADSEENKNTDQHQATSRWRKFS
                     REWIRTAKSDSLDIS"
     gene            complement(1711..5220)
                     /gene="hsdR"
                     /locus_tag="OPY25_004167"
     CDS             complement(1711..5220)
                     /gene="hsdR"
                     /locus_tag="OPY25_004167"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system
                     endonuclease"
                     /protein_id="HCS0929628.1"
                     /translation="MNKSNFDFLKGVNDFIYAIACAAENNYPDDPNTTLIKMRMFGEA
                     TAKHLGQLLDIPVCENQHDLLRELGKIAFIDDSILSVFHKLRRIGNLAVHEFHNDLDD
                     AQMCLRLGFRLSVWYYRLVTKDYDFPVPMFVLPEHGENLYHQEVLTLKQQLERQAQEK
                     VQSQAELEAQQQRLVALNGYIAILEGKQQETEAQTKARLAALEAQLAAKDAELAKQTE
                     QERKAYHKEITDQAIKRTLNLSEEESRFLIDAQLRKAGWQADSKTLRFAKGARPEPGV
                     NKAIAEWPTGTDETGKTGFADYVLFVGLKPIAVVEAKRKNTDVFSKLNESYRYSKYFD
                     NGFLRDTLLEHYAPDEVHDAVPEYEISWQDTSGKQRFKIPFCYSTNGREYRAAMKTKS
                     GIWYRDVRHTTNMSKALPEWHRPEELLDMLGSDPQKQNQWFAENPGMSELGLRYYQED
                     AVRAVEKAIVNGQQEILLAMATGTGKTRTAIALMFRLIQSQRFKRVLFLVDRRSLGEQ
                     ALGSFEDTRINGDTFNSIFDIKGLTDKFPEDSTKIHVATVQSLVKRTLQSDEPMPVGR
                     YDCIVVDEAHRGYILDKEQTEGELQFRSQLDYVSAYRRILDHFDAVKIALTATPALHT
                     VEIFGEPVYRYTYRTAVIDGYLIDQDPPIQIVTRNAQDGVYLSEGEQVERLNPQGELI
                     NDTLADDQDFEVADFNRGLVIPAFNRAVCGELTKYLDPIGQQKTLVFCVTNAHADMVV
                     DELRTAFKKKYPQLEHDAIIKITGDADKDAKKVQSMIVRFNKERLPNIVVTVDLLTTG
                     VDIPSICNIVFLRKVKSRILYEQMKGRATRLCPSVGKTSFKIYDCVDIYSSLESVDTM
                     RPVVVRPQVELQTLVNEITDSETYKTIEADGRSFAEHSHEQLVAKLQRIIGLATYNRD
                     HSETVDKQVRRLDELCLDAAGVNFGGLASRLREKGPHWSAEIFNKLPGFIARLERLKT
                     DINALRDAPIFLDIDDEVVSVKSLYGDYDTPQDFLEAFDALVQHAPNAQPALQAVINR
                     PRDLTRKGLVELQEWFDRQHFEESSLRSAWKETRNEDIAARLIGHIRRAAVGDALKPF
                     DERVDHALARIKGENDWSPEQLSWLDRLAQALKEKVVLDDDVFKTGNFHRRGGKSMLQ
                     RTFDDNLDSVLDKFSDYIWDELA"
     gene            5418..6332
                     /locus_tag="OPY25_004168"
     CDS             5418..6332
                     /locus_tag="OPY25_004168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HCS0929629.1"
                     /translation="MAVPTYDKFIEPVLRFLATRPEGALVREVREAAAEMLGLNEQQR
                     AEVITSGQLTYQNRTGWAHDRLKRAGLSQSLSRGKWCLTPAGMSWVASHPQPMTEQEV
                     SHFACDFNGVKLSKPADAVALDPQPESIEDDELARSSPDDRLEQALNEIRESVAEELL
                     ENLLQVSPARFEVIVLDVLHRLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYV
                     QAKRWKGTVGSAEVRGFYGALPEQKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDR
                     LVHLMIDNDIGVSSRLLKLPKLDMDYFE"
BASE COUNT         1332 a         1731 c         1826 g         1628 t
ORIGIN      
        1 aactggcgct gcgcatccgc ctcatcgccc gcgcccagct ctcgcatcag tgcatccagc
       61 tcgcccagcg cctgcaccag ctcgcccatc gcttctgcgg ctaacacgtc cggttccggc
      121 aggctgtcgg cgtcgatgct gtccttatcc ttcagctagg agatatccag cgaatcggat
      181 tttgccgtgc ggatccactc gcggctgaac ttgcgccagc ggctggtggc ctggtgctga
      241 tcggtgtttt tgttctcttc gctgtcagca acttccgtct cttcagcgtt aaaactccac
      301 tcaccttcgg ctcgtgggct taagccgtgc ggatcctcac catagacggt ttcaaacggc
      361 tgcaggtatt gctcagtaaa cggtgtacgc ttaccaaatc tcggcatatt ggtgcgcagg
      421 tcgtacaccc acacgtcatc ggtacagtcc ttatcctgag tcggattggc taccgtacct
      481 ttggtaaaga acagcacgtt ggttttgacg ccctgggcgt aaaagatgcc ggtcggcaga
      541 cgcaggatgg tgtgcagatg gcatttgtcc attaaatctc gacgaatttc caatccaact
      601 cgatcaaata gtacgttatc cggcaccacc actgccgcac ggccgccggg gcgcagggtt
      661 tcgataatat gctgcataaa gcaaagctgt ttgttgctgg tcgggtgcac gaaggtgcgg
      721 gtaatgttgg tgcccgcggc gctgccaaac ggcgggttgg tggcgacaat atcggcctgc
      781 ggtaaattct cgccgtcgct gcccagcgtg ttgcccagac ggatggcgcc gccgtggtcg
      841 aggttgcctt caatatcgtg cagcagacag ttcatcagcg ccagacgacg ggtgccgggc
      901 accagctcga ggccgataaa cgcgcggtgg atctggaaat cctgggtgtc gccatcaagg
      961 tcatccagat cgttggtctg cgacttcacg taacggtcgg cttcaatcaa aaaacctgcg
     1021 gtcccggcag ccgggtcctg caccacctca cgcggctgcg gcttcagcag atgaataatg
     1081 gttttgatca gcggacgcgg ggtgaagtac tggcccgcgc cggatttggt ttcgttagcg
     1141 ttcttctgca gcagcccttc gtacatatcg ccgaagtcgt cgcgggactt gccgcgtgta
     1201 ccgctgtacc agtccagcga atccatgttg ctgactaatt ctgttatctg tttgggttca
     1261 gtgatggttg tacacacatt atgaaatacc gcctgcacca gttttttctt atcttccccc
     1321 agatgcacca gcattttacg gtaaaactgc aactgctcct ggtcaatgcg cgatttcagg
     1381 tcatcccagc ggtagccttc cggcaggtag tccgcttcct gaccggtctc tttgcacatt
     1441 ttcaaaaaca gcagcgaggc gagttcattg gcgtagtttt gataggagac gccgccgtcg
     1501 cgcaggttgt cgcacagttt ccacagcttg gcgaccagat cgttattgtt cattgaagat
     1561 cccatttgac atggcgacca ccattgtggg tcgcaaaagt gattgagcat ttcagatgcc
     1621 tgatggcgct tcgcttatca ggcctacagg gttacgtgta ggccggataa ggcatcgccg
     1681 ccatccggcg aaaacgggga tgataccctc ttaagccagc tcgtcccaga tataatcgct
     1741 gaacttatcc agcacgctgt cgaggttgtc gtcaaaggtg cgctgtaaca tggacttacc
     1801 gccgcgacgg tggaaattgc cggttttgaa gacgtcgtcg tcgagcacca ctttctcttt
     1861 cagcgcctgc gctaaacggt cgagccagct tagctgctca gggctccagt cgttctcgcc
     1921 tttgatacgc gccagcgcgt gatcgacacg ctcgtcgaac ggtttgagcg catcgcccac
     1981 cgccgcacgg cggatatggc cgatcaggcg ggcggcaata tcttcattgc gtgtttcttt
     2041 ccacgcgctg cgcagagagg actcttcaaa atgctggcgg tcaaaccact cctgcaattc
     2101 caccagccct ttacgggtga ggtcacgcgg acgattgatc accgcctgca gcgccggctg
     2161 ggcgttaggg gcgtgttgca ccagcgcatc gaacgcttcg agaaagtcct gcggcgtatc
     2221 gtagtcgccg tacagcgatt tgacgctcac cacctcatcg tcaatatcga ggaagatcgg
     2281 cgcatcgcgc agggcgttga tatcggtttt cagcctttcg aggcgggcga taaaaccagg
     2341 aagcttattg aaaatctcgg cgctccagtg cggccctttt tcccgcaggc gcgaagccag
     2401 accaccaaag ttaacgcccg cggcatccag gcacagttcg tccagacgac gtacttgctt
     2461 atccaccgtt tcgctgtggt cacggttata ggtggcaaga ccgataatcc gctgcagctt
     2521 agcgaccagc tgttcatggc tgtgttcggc aaaactgcgg ccatccgctt caatggtttt
     2581 gtaggtttct gagtcggtaa tttcgttgac cagcgtttgc agctccacct gcggacgcac
     2641 aaccaccggg cgcatggtgt cgacgctttc cagcgaactg tagatatcca cgcagtcgta
     2701 aatcttaaag ctggttttcc ctaccgacgg gcacaaacgc gtggcacggc ccttcatctg
     2761 ctcgtagaga atgcggcttt tgactttgcg caggaacaca atattacaga tagacggaat
     2821 atccacaccg gtggtcagca gatcgacggt gaccacgata ttgggcaacc gctctttgtt
     2881 gaaacggacg atcatgcttt gcactttctt cgcgtcttta tcggcatcac cggtgatctt
     2941 gatgatcgcg tcgtgctcaa gctgcggata ctttttctta aacgcggtac gcagttcgtc
     3001 aaccaccatg tcggcatggg cgttggtgac gcagaacacc agcgtttttt gttgcccgat
     3061 gggatccagg tatttggtga gctcgccgca taccgcgcgg ttaaacgccg ggatcaccag
     3121 gccacggtta aagtcggcga cctcaaaatc ctgatcgtcg gccagcgtgt cgttgatcag
     3181 ctcgccctgt gggttcaggc gctccacctg ttcaccctcg gaaagataga ccccatcctg
     3241 cgcgttgcgg gtgacgatct gaataggggg atcctgatcg atcaggtaac cgtcgatcac
     3301 cgccgtacgg taggtgtagc ggtaaaccgg ttcgccgaaa atctccactg tatgcagcgc
     3361 tggcgtggcg gtcagggcga tttttaccgc atcgaaatgg tcgagaatgc gacggtaggc
     3421 ggaaacgtaa tccagctggc tgcggaactg cagctcgccc tcggtttgct ctttatcgag
     3481 aatgtagccg cggtgtgctt catcgacgac gatacagtcg tagcggccaa ccggcattgg
     3541 ctcatcggat tgcagcgtac gcttgaccag tgactgcacc gtggcgacgt gaattttggt
     3601 gctgtcttcc gggaatttgt cggtcaaccc tttgatatca aaaatgctgt taaaggtgtc
     3661 gccgttaatg cgcgtgtctt caaacgaccc cagcgcctgt tcgccaagcg agcgacggtc
     3721 gaccaggaaa agaacgcgtt tgaaacgctg cgactggatc aggcggaaca tcagggcgat
     3781 ggcggtacgg gttttaccgg taccggtcgc catcgccagc aggatctctt gctggccgtt
     3841 aacgatagcc ttttccaccg cgcggacggc atcctcctgg taatagcgca ggccgagttc
     3901 gctcattccg gggttttcag caaaccactg gttttgtttc tgcgggtcgc tgcccagcat
     3961 atccagcagc tcttccgggc gatgccattc cggcagcgct tttgacatat tggtggtgtg
     4021 tcggacatcg cgataccaga taccgctttt ggtcttcatc gctgcgcggt attcgcgccc
     4081 gttggtggag tagcagaagg ggattttaaa gcgctgtttg ccgctggtgt cctgccagct
     4141 gatttcatac tctggcacgg cgtcatgcac ttcgtcggga gcgtagtgct ccagcagcgt
     4201 gtcgcgtaaa aatccgttat cgaagtattt actgtagcgg taagactcgt tgagcttgct
     4261 gaagacatcg gtatttttgc gtttcgcttc aacgacggcg atgggcttca ggccaacgaa
     4321 caatacgtaa tcggcaaagc ctgtttttcc cgtttcatct gtacccgttg gccattcggc
     4381 aatcgcttta ttgacgccgg gttccgggcg agcgcctttg gcaaagcgca gcgttttact
     4441 gtcggcctgc cagcccgctt tgcgcaactg ggcgtcgatc aggaagcggc tctcttcttc
     4501 gctgagattc agcgtgcgct tgatagcctg atcggtgatc tctttgtgat aggccttacg
     4561 ttcctgttcg gtttgcttcg ccagttcggc atcttttgcc gcaagctgtg cctccagcgc
     4621 ggccagacgt gctttggtct gggcttcggt ttcctgctgt ttgccctcaa ggatggcaat
     4681 gtagccgttg agcgcaacca gtctttgctg ctgagcttcc agttcggcct gactttgtac
     4741 tttctcttgc gcctgacgtt ccaactgttg tttcagcgtc agcacttcct ggtgataaag
     4801 attctcgccg tgttctggca gaacaaacat cggcaccggg aaatcgtaat ctttggttac
     4861 cagtcggtag taccagacgc tgaggcggaa cccgagccgc aggcacatct gggcatcgtc
     4921 cagatcgtta tgaaattcgt ggacggccag gttaccgata cggcgcagct tatggaaaac
     4981 agaaaggatg ctgtcatcaa taaacgcaat cttgcccagt tcgcgtagca ggtcatgttg
     5041 gttttcgcag acgggtatat ccagcaactg gccgagatgt ttcgcggtgg cttcgccaaa
     5101 catgcgcatt tttatcagag tggtattagg atcgtccgga tagttgtttt ccgccgcgca
     5161 ggcgatggcg taaatgaagt cgttgacgcc tttgagaaag tcgaagttag atttgttcat
     5221 ttttatctat ccggttcctg agcgggaaga cgttattacc ttgtgccgta aagggaaaat
     5281 aacagaccca tggtagactt catattgtgt gtgatcaacg aacaatcaga gagtaactgc
     5341 ttctttccta atgttttcct gaagagtatc gttctccggc ggggtatcta atctatatca
     5401 atagcaggga tggatttatg gctgttccaa catatgacaa atttattgaa ccagtgttgc
     5461 gttttctggc cactcgaccc gagggcgctt tggtcagaga agtgcgtgaa gctgcagccg
     5521 aaatgcttgg gttaaatgag cagcagcgtg cagaggtgat taccagtgga caactgacgt
     5581 accagaaccg caccggttgg gcgcacgatc gtctcaaacg cgccgggtta tcgcagagcc
     5641 tatcccgggg aaaatggtgt ttaacaccag cgggaatgag ctgggttgcc tcgcatccgc
     5701 agccgatgac cgagcaggaa gtgagtcatt ttgcttgtga ttttaacggc gtaaagctca
     5761 gtaagccggc agatgcggtg gcgttagatc cacagccaga atcgattgag gatgatgagc
     5821 ttgccagaag cagcccggac gatcgcctgg agcaagcgct caatgagatt cgtgaatctg
     5881 ttgccgaaga attgctggag aacctgcttc aggtttcgcc ggcgcgtttt gaagtgattg
     5941 tgttagatgt gttgcaccgc ctgggatatg gcggtcatcg cggtgatttg cagcgcgtcg
     6001 ggggaaccgg cgatggcggc attgacggta ttatctctct cgataagctc gggctggaaa
     6061 aagtctacgt tcaggccaaa cgctggaaag gcaccgtcgg gagcgctgaa gtcaggggct
     6121 tttatggtgc attgcctgag caaaaagtga aacgtggcgt ctttattacc acctcaggct
     6181 ttacggcgca tgccagagac tatgctaaca aagttgaagg tctggtgctg gtggatggcg
     6241 acaggctggt gcatctgatg attgataatg atattggcgt atcctcacgt ttactcaagt
     6301 tgccaaagct cgatatggat tactttgagt agtggtaacg ctggaacctg attacgggta
     6361 attgagatgg accacgttgt gggcacctgt gtttcctctc gcccagaaat cacgtgactt
     6421 tctatggctg cgtatcagcc taaacccatg ccttctgcgg cctactcttc tggtcaattt
     6481 tcttttatct cgaatacgca aattgtgaag ctatttc
//
LOCUS       DAJVKX010000185         6489 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.185, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000185 DAJVKX010000000
VERSION     DAJVKX010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6489
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.185"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(68..1786)
                     /gene="proS"
                     /locus_tag="OPY25_004169"
     CDS             complement(68..1786)
                     /gene="proS"
                     /locus_tag="OPY25_004169"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCS0929630.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGE
                     DDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVKDSKSPLVALLVRGDHELNEVKAEKLPHVASPLTFATEEEIRAVINAG
                     PGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     MDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGEKSLIKTGDIVDYL
                     VKAIKG"
     gene            complement(1897..2604)
                     /gene="tsaA"
                     /locus_tag="OPY25_004170"
     CDS             complement(1897..2604)
                     /gene="tsaA"
                     /locus_tag="OPY25_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HCS0929631.1"
                     /translation="MSSFQFDQIGVIRSPYKEKFAVPRQPGLVKSACGELHLIAPYNQ
                     ADAVRGLEAFSHLWVLFVFHQTMDGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVALKGIECRKESVILKLGSLDLVDGTPVVDIKPYLPFAEALPDAAASYAQQAPIAE
                     MPVSFTAEVAQQLTTLERRYPQLRTFICDVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVVNTGFEVFALEPR"
     gene            complement(2601..3005)
                     /gene="rcsF"
                     /locus_tag="OPY25_004171"
     CDS             complement(2601..3005)
                     /gene="rcsF"
                     /locus_tag="OPY25_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HCS0929632.1"
                     /translation="MRALPICLLALMLGGCSMLSRSPVEPVQSTATPPKAEPEKPKAP
                     RAAPVRIYTNAEDLVGKPFRDLGEVSGESCQATNQDSPPNIPTARKRMQINASKMKAN
                     AVLLHSCEITSGTPGCYRQAVCIGSALNISAK"
     gene            complement(3124..3939)
                     /gene="metQ"
                     /locus_tag="OPY25_004172"
     CDS             complement(3124..3939)
                     /gene="metQ"
                     /locus_tag="OPY25_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HCS0929633.1"
                     /translation="MAFKFKTFAAVGALIGSLALAGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQIKDRGYK
                     LVSVGKTFVYPIAGYSKKIKSLDELKDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VSLLPTSLDIVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKDSPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(3978..4631)
                     /gene="metI"
                     /locus_tag="OPY25_004173"
     CDS             complement(3978..4631)
                     /gene="metI"
                     /locus_tag="OPY25_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HCS0929634.1"
                     /translation="MSEAMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIMENARLYRSLSAVVNIFRSIPFIILLVWMIPFTRIIVGTSIGLQAAIVPLTVGAAP
                     FIARIVENALLEIPAGLIEASRAMGATPLQIVRKILLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVVLVYLIQLSGDRIVRAVTHK"
     gene            complement(4624..5655)
                     /gene="metN"
                     /locus_tag="OPY25_004174"
     CDS             complement(4624..5655)
                     /gene="metN"
                     /locus_tag="OPY25_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HCS0929635.1"
                     /translation="MIKLSNITKVFQQGARTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVMVGGQELTTLSESGLTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKEEIKRRVTELLDLVGLGDKHDSYPANLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQARLKASPETDSVPMLRMEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQEETQAAIAWLQDHH
                     VKVEVLGYV"
     gene            5845..6411
                     /gene="gmhB"
                     /locus_tag="OPY25_004175"
     CDS             5845..6411
                     /gene="gmhB"
                     /locus_tag="OPY25_004175"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HCS0929636.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDAFEFIDGVIDAMRELKK
                     MGYALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSIEE
                     FRQVCDCRKPHPGMLISARDFLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKP
                     VTAEAENAADWVLNSLADLPSAIKKQQK"
BASE COUNT         1577 a         1705 c         1680 g         1527 t
ORIGIN      
        1 gcctcgcagg gtgcgaggcc tttacatatc tgccggatgg cgccgggcaa tcccaacaaa
       61 atgtcgttta gcctttaatc gccttgacca gataatcaac gatatcgccg gttttaatca
      121 gcgatttttc accgctacga cggtatttat actcaatatc gtcgttatcc aggttgcgat
      181 cgccaatcac gatagtatgt ggaataccaa tcagctccat atcggcaaac atcacgcccg
      241 ggcgctcttt acgatcgtcc atcagcactt caatgccctg cgcgcgcaat tcgctgtaca
      301 gcttttccgc cagctcctgc acacggaagg atttgtgcat attcatcggc agaatagcga
      361 cctggaaagg tgcaatggcg tcaggccata caatgccgcg ctcgtcaaag ttctgctcga
      421 tagccgcggc aacgacacgt gttacgccga taccatagca gcccattgtc aggatctggt
      481 tacggccatc ttcaccctga acggaggctt tcagcgcttc tgagtacttg gtacctaact
      541 ggaagatgtg acccacttcg ataccgcgtt tgataagcaa cgttccctga ccatccggac
      601 tcggatcgcc ggcgactacg ttacggatgt cggcaacaac aggcgtcgcc acatcgcgat
      661 cccagttaat accaaagtag tgtttaccgt cgatgttagc gccagcggca aaatcgctca
      721 tggcggcaac ggtacgatcg atgatgaccg gaatcggcat attgaccggg ccgagggagc
      781 cagggccggc attaattacg gcgcgaatct cttcttcagt agcgaaggtc agcgggctgg
      841 caacgtgcgg cagtttttcc gctttaactt cattcagttc atgatcgccg cgaaccagca
      901 gagccaccag cggagacttg ctgtctttca ccgctttcac cagcagcgtt tttaccgttt
      961 tttcaattgg caggttgaat tgttccacca gctccgcgat ggttttggca tttggcgtat
     1021 cgaccagagt catttcctgc gtcgccgctg cgcgcggtgt ttgcggcgcg atagcttctg
     1081 ccagttcaat gttagccgcg taatcagaaa catcagagaa aacgatatcg tcttcgccgc
     1141 tttgcgccag cacctggaat tcatgcgagg cgttgccgcc gatagaaccg gtatcggcct
     1201 gtaccgcgcg gaaatccagc cccatacggc tgaagatacg gctatacgcg gcgtacatgg
     1261 cgtcataggt ttcctgcaac gactcctgag aggtgtggaa agagtaagca tctttcatca
     1321 ggaattcgcg cgaacgcatc acgccaaagc gcggacgcac ttcatcacgg aatttggtct
     1381 ggatttggaa gaagttcagc ggcaactgct tataagagct gagttcatta cgcaccaggt
     1441 cggtgataac ttcttcgtgg gtcgggccga gtacgaacgg acgctcgcca cggtcgacaa
     1501 aacgcagcag ttccggaccg tactgttccc aacgaccact ctcttgccac aggtcggctg
     1561 gctgaacgac tggcatcgac acctcgatag caccggcgtt gttcatctct tcacgcacga
     1621 tgttttcgac ttttttcagg acgcgcaggc cggtcggcag ccaggtatat aacccggagg
     1681 cgagcttgcg gatcatcccg gcgcgcagca tcagctggtg gctgataacc tcggcgtcgg
     1741 caggtgtctc cttcagagtg gagagcaggt attggctagt acgcatgttg ttacggttcc
     1801 agttgaacga tcgaacaggc tcaatgtgag cctgatacaa aaaaagtgat ttagtttacc
     1861 agcgtgcaag agatgtcaaa agagaagggc gtgaaattac cgtggttcca gcgcaaacac
     1921 ttcaaatccg gtgttaacca cacgccagcg cacgttaaaa tcatgcagcc agacggcata
     1981 ggttttgccc gtctcttcac ccttacgata agccgggcga ggatcttgcg ccagcacatc
     2041 gcaaataaat gtccgtagct gcggataacg cctttccagc gtcgtaagct gttgagccac
     2101 ttcagcggta aaactcacag gcatttcagc tatcggcgcc tgttgcgcat agctggcggc
     2161 ggcgtccggt aaggcctcgg caaacggtaa atacggtttg atatccacca ccggcgtgcc
     2221 atccaccaga tccagactgc ctaatttcag aattacgctc tctttccggc actcgatacc
     2281 ttttagcgca acgagcgaca tgccaatcgg attggggcgg aacgtggagc gcgtggcaaa
     2341 aacgcccatt ctggcgttac cgccaagacg gggcggacga actgttggcc gccagccgcc
     2401 gtccatcgtc tgatgaaaaa cgaaaagcac ccacaaatgg ctgaacgctt ccaggccgcg
     2461 aacggcatcg gcctggttgt aaggcgctat cagatgcagt tcgccgcagg cgcttttgac
     2521 cagaccaggc tggcgcggaa cggcgaattt ttctttatag ggggagcgaa taacgccgat
     2581 ttgatcaaac tgaaagctgc tcatttcgcc gaaatattca gggcggaccc gatacaaacc
     2641 gcctgacggt agcagcctgg cgtgccgctg gtaatttcac agctgtgcag caggacggcg
     2701 ttggctttca ttttagatgc attaatctgc atacgcttgc gcgcagttgg aatgttaggc
     2761 ggagagtctt gatttgtcgc ctggcaggat tcgccgctaa cctcgccaag atcgcggaaa
     2821 ggtttgccga ctaagtcttc agcattggtg taaatcctga cgggagcggc acgcggcgct
     2881 ttaggtttct ccggctccgc ttttggcggg gttgcggtgc tttgaacggg ttcaacaggg
     2941 gatctgctta gcatggaaca accgcccagc atgagtgcca ataaacagat cggtaaagca
     3001 cgcataatat ttcctcaatg aatgttctaa ttgccagata ttgaatcagg agcttgcata
     3061 aatgacaaga cgggcaatag cccgtcctga ataatattac agattgtgga atcagcctaa
     3121 aacttaccag cctttcaccg cgccgccatt aaaaacttta tttgcggctt cgtacacttc
     3181 atcagactgg taagcctgaa cgaatttttt cacattctcg gcgtctttgt tatcttcacg
     3241 cgtcacgatc aagttaacgt acggagaatc tttatcttca acgaagatac cgtctttcgc
     3301 tggcgtcagg ccaatctggc tggcgtaagt cgtattgatg accgctaacg cgatctgagc
     3361 gtcatccagc gaacgcggca actgcggcgc ttccagctca acaattttca gatttttcgg
     3421 gttttcgacg atatccagcg aggtaggaag cagactgacg ccgtctttca gtttaatcag
     3481 ccctactttt tgcagcagca gcagggaacg accaaggttg gtcgggtcgt taggcacagc
     3541 gacctgggaa ccgtccttga gctcatccag agatttgatt tttttggaat atcctgcaat
     3601 gggatagaca aaagtcttac caacggaaac cagtttgtag ccgcgatctt tgatttgctg
     3661 atccagatac ggtttgtgct ggaaggcatt ggcatcgata tcgcctttgc tcagcgcttc
     3721 attaggcaga acataatcat taaaggtcac caattccacg tccaggccgt atttttcttt
     3781 cgcgactttc tgcgcgactt cggcaacttg ctgctctgcg ccaacgatta cgccgacttt
     3841 aatatgattc ggatcttttt catcctgacc gcaacccgca agtgccagag aaccaatcag
     3901 agcacccact gccgcaaagg ttttgaattt gaacgccatg cttatttcct taatgagtat
     3961 ttgtgttgtg tttaacgtta cttatgcgtg acagccctga cgatgcgatc gccggataac
     4021 tgaattaaat aaaccagaac gacaagtaat accagcaccg tattcatcac ggtagcattg
     4081 tatccaatat aaccgtactg atagccgatt tgaccgaggc cgcctgcgcc gacggcgccg
     4141 cccattgcgg agtaaccgac cagggtgatt agtgtaatgg ttgccgcatt caccagacca
     4201 ggcagcgctt ccggtaaaag gattttacgt acaatttgca gcggcgtggc gcccatcgct
     4261 cgcgaggctt caatcagccc ggcagggatc tctaacaacg cattttccac tatacgggcg
     4321 ataaaaggcg cggcgccgac ggtcagcggt acaatcgcgg cctgcaaacc aatggaggtg
     4381 ccgacaatta ttcgggtaaa aggaatcatc cacaccaaca ggatgataaa gggaatcgag
     4441 cggaaaatat tgaccaccgc agagagggag cgatacagcc tggcgttctc cataatctgc
     4501 cccgggcgcg taacatacag caatacgcca accggcaggc caatcacgaa accgaagaaa
     4561 ccggagacaa aggtcatcgc cagcgtttcc cagacgccac gaaccagtaa ccacatcatt
     4621 gcctcagaca taacccagta cctctacttt cacatggtga tcctgcagcc aggcaattgc
     4681 ggcttgcgtc tcttcttgtg tgccgtgcat ttccgttagc ataatgccga acttcacacc
     4741 gcccgcgtaa tccatctgtg cgctgataat attattgttc acgttgaaac gacgcgcggt
     4801 ttcagaaagc agcggggcat ccacagactg tccggtgaac tccatgcgca gcatcggcac
     4861 gctgtcagtt tccggcgacg ctttcaaacg cgcctggtaa tcttccggaa tgtccagatg
     4921 cagagtggac tgaataaact tctgcgccag cggcgtttta ggatgcgaga agacttcgct
     4981 gaccgtatcc tgctcaataa gctcgccatt actgatgacg gcaacgcagt cgcagatacg
     5041 ttttacgaca tccatttcat gagtgataag cagaatcgtc aaccccagac gacggttgat
     5101 atctttcagc aattccagaa tcgaacgggt cgtcgcggga tcaagcgcgc tggtggcttc
     5161 atcgcacagc aacacttttg gattactggc taacgcgcgg gcaatcgcga cacgctgttt
     5221 ctgaccgccg gaaagatttg ccggatagct gtcgtgcttg tcgccaagac cgactaaatc
     5281 cagcagctct gtgacacggc gtttgatctc ttcctttggt gtgttatcca gttccagcgg
     5341 caacgcgacg ttgccaaaca cggtacggga agagagcagg ttaaaatgtt ggaaaatcat
     5401 gccgatttga cggcgagctt tggtcaaccc ggactctgaa agcgttgtca gctcctgacc
     5461 gcctaccatt acgcttcctt cagtaggacg ttcaagtaag tttacgcagc gaatgagcgt
     5521 acttttaccg gcgccggagg cgccgatgac gccgtaaatt tgtccggcag ggacatgcag
     5581 gctgacattg ttcagcgcct gaatggtgcg cgccccctgc tggaacactt tggtaatatt
     5641 cgaaagttta atcattgatt ctttattatc gtaatgaaat gagcggaggc attttcgtct
     5701 gcctaatacg gtcaacgccg tcaacagaat ggatgttaag gcatccagac gtctaaatca
     5761 atcaggcttt atacgatgag cactttcttg cctgctgaaa catgcgatac tagcgccact
     5821 tgctttactc aggagctata aaaggtggca aagtctgtac ccgcaatttt tctcgaccgt
     5881 gacggcacca ttaatgtgga tcacggctac gtacatgaaa tcgatgcatt tgagtttata
     5941 gacggcgtta ttgacgcgat gcgcgagcta aaaaaaatgg gctatgcgct ggtggtggtg
     6001 acgaaccagt ccggaatcgc gcgcggcaaa ttcactgagg cgcagtttga aacgttaacc
     6061 gaatggatgg actggtcgtt ggcggatcgc gatgttgatt tggacggcat ctattattgt
     6121 cctcaccatc cgcagggcag catagaagag ttccgtcagg tatgtgattg ccgcaagccg
     6181 catccaggaa tgcttatctc ggcgcgtgat ttcctgcata tcgatatggc ggcttcttat
     6241 atggtgggag acaagctgga agatatgcag gcggcagcgg cggcaaatgt cgggacaaaa
     6301 gtgctggtgc gtacgggcaa accggtcacg gcagaagcag aaaacgcggc ggactgggtg
     6361 ttaaacagcc ttgctgacct gccatcagcg ataaaaaagc agcaaaaata agcgttatgg
     6421 ataaaagatg agcggttaaa acaaaaatgc atttttccgc ttgtcttcct gaaccgactc
     6481 cctataatg
//
LOCUS       DAJVKX010000186         6414 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.186, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000186 DAJVKX010000000
VERSION     DAJVKX010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6414
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.186"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(510..908)
                     /gene="vapC"
                     /locus_tag="OPY25_004176"
     CDS             complement(510..908)
                     /gene="vapC"
                     /locus_tag="OPY25_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(fMet)-specific endonuclease VapC"
                     /protein_id="HCS0929637.1"
                     /translation="MLKFMLDTNTCIFTIKNKPEHIRERFNLNTSRMCISSITLMELI
                     YGAEKSLAPERNFAVVEGFISRLEVLDYDTQAAIHTGQIRTELARKGTPVGSYDQMIA
                     GHARSRGLVVVTNNLREFERIPGIRIEDWC"
     gene            complement(908..1135)
                     /gene="vapB"
                     /locus_tag="OPY25_004177"
     CDS             complement(908..1135)
                     /gene="vapB"
                     /locus_tag="OPY25_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin VapB"
                     /protein_id="HCS0929638.1"
                     /translation="MHTTLFFSNRTQAVRLPKSISFPEDVKHVEIIAVGRSRIITPVG
                     ESWDSWFDGEGASTDFMSTREQPAVQEREGF"
     gene            1312..1563
                     /locus_tag="OPY25_004178"
     CDS             1312..1563
                     /locus_tag="OPY25_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929639.1"
                     /translation="MHKKHMCPWLLPGLLGLARCAPVPHTYAAIIEAGFYPEGTDLQL
                     VLKIIETARQEIRLMDYSFTSWEVVRFEHSVSTKFSMSK"
     gene            1838..2644
                     /locus_tag="OPY25_004179"
     CDS             1838..2644
                     /locus_tag="OPY25_004179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1460 domain-containing protein"
                     /protein_id="HCS0929640.1"
                     /translation="MIMKVNAWTILLMSAHLTACAVPGTEKYQTSMDSVTAEKISRII
                     QSDVIPYKGENHGEVISRVSSAFLGTPYQADTLIGGPGIPEVLVANFNGVDCFTLADY
                     VEALARSDNQKSFLHNLARTRYAAGKVAYLSRRHFFSDWFAAAPRNARDVTPDISPDY
                     VVVDKQLNHKPDGGEYIPGLGIHPRKINYIPGRAINQQVMNHLKNGDYIGVYSPLDGL
                     DVSHVGIVVRHDEQVWFRNASSLAANRKVVDTPFMEYMHSRLGIVVLRAE"
     gene            complement(3277..4398)
                     /locus_tag="OPY25_004180"
     CDS             complement(3277..4398)
                     /locus_tag="OPY25_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929641.1"
                     /translation="MSITNQINKASSLASLRQPQRDKDGQIIKGSIWGTDISRTDYVQ
                     MTNGQDAQVLNVGFTDRSGRPMAFGNDSHDFVQALEDSLDETFNDGDFRTAVMENVFP
                     CEFRPYGTDPTPIRRQALQNRTVRFKHNGAFNPAKDAPSTTAIKGASVTVTPVLNPET
                     NKTGILCSAATHVSDFDMMGGWTEGALIQTVGDMQVQYSRQMFAAVVDVLKDTPDLQI
                     IEAAPLSGKPSDQAEDLLDTLALNLPVELGNTLSDYAVLVPERLEAILDRAAQRAGHE
                     DISELLGCTVCSYAGDDTGVYLLPKRFASISFRSTKDAKTVDVKVTRNSNTAGYDLEL
                     ISVVDVLATGSVKVKAGEFDVEKDASFPLIHVIRFTTPE"
     gene            complement(4500..4910)
                     /locus_tag="OPY25_004181"
     CDS             complement(4500..4910)
                     /locus_tag="OPY25_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929642.1"
                     /translation="MSISYRKLDIALSADKETVLVFGQELSTKYFTEIVVTTMLNSTG
                     SDMANSNRILNDIHAAGLDAGDYGKYSRWWAQSNAQERQEAERRRKEAKAHQERMAAI
                     HATPEEIAKAVAERKAREEALIKRFGNKGAAFGL"
     gene            complement(5245..5964)
                     /locus_tag="OPY25_004182"
     CDS             complement(5245..5964)
                     /locus_tag="OPY25_004182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HCS0929643.1"
                     /translation="MSQQEISIINLDQLVSMTSVEIAELTGKEHRNVLRDIRNMVEEL
                     NALKTEHCSKLSSPIGVIEDVYLNAQGKQQPLYRLDRKHTFILVAGYSVHLRAKCYDH
                     IQTLERRVLQLEDQKKRAAIQSANRRGVTWGDYCKANGLPAQKLMTILKKERKLFRVH
                     SSSGEWSVNPNYVEYFRIIKPTDHRFNPNGINIRFNAKGLEFFSRPENVLKMHRKVIA
                     VHGSDAAKQQHIQAVAKLEGR"
BASE COUNT         1656 a         1522 c         1558 g         1678 t
ORIGIN      
        1 ataactatgt gactggggtg agcgacaaat ctgccgggag cagatttgaa cgtcgcgtgc
       61 gacggcccgt cagggcgagg cccatggatg ggccgagtaa tccgtagcca acacataaac
      121 aacttgaagt atgaagggta tataacggga aagaagccat atcggcctgg taaatcaacg
      181 tctgtgattt aagttgcagg aaacggctat ggagagggga tgcggcagtt atcgggcagt
      241 aacggcattg ttcagtgagt atccaggaaa caaaaaaaga agggagcggt actcccttcg
      301 taaccatgtc agaatacgac attttggtac tcttttattt attatctggc cgtaaaagtt
      361 atgctgttgg cagatatctc cagtcaacat aaaaaaatac caccagctaa aaatgtgatg
      421 caaaccacca ttaagcaggt aaccaaattg actgtgccac tacaatccgg aaaagagttt
      481 gaatccgggg ataacatctg atgcagaaat tagcaccagt cttcgattcg gatacccgga
      541 atgcgttcaa actcgcggag attgtttgtg acgacgacca gtccgcggct acgggcatgg
      601 ccagcaatca tctggtcata agacccgaca ggtgttccct tgcgggccag ttcggtacgg
      661 atttgaccgg tatgtatcgc tgcctgtgta tcgtaatcca gaacctcaag gcgggagata
      721 aatccctcca cgactgcaaa attacgctcc ggtgccaggc ttttttcagc accgtaaatc
      781 agctccatta aggtgatgga gctgatacac attcgggatg tattgaggtt gaagcgttct
      841 ctgatgtgtt cgggcttatt tttgatggtg aaaatacaag tattggtatc aagcatgaat
      901 ttcagcatca gaatccttcc cgttcctgta ctgcgggttg ttctctggtg ctcataaaat
      961 cagtactggc gccttcgcca tcgaaccagc tgtcccagga ttctccgact ggagtaatga
     1021 ttctgcttct accaaccgca atgatttcga catgtttcac atcctccgga aaggatatcg
     1081 atttaggcaa tctgactgcc tgggtccggt tactaaaaaa aagtgttgtg tgcataactg
     1141 ccccctttct ggatatacaa cgcgtatatc cattatgagt agaggcgatg tatatgtcaa
     1201 agagatatac aggaaaaaat aatccagtca catgacgcgc actccgcagg gcatccttgt
     1261 ccgactccgg catttctgaa tacatccaat gaaggaaata ccatgcaaac aatgcataaa
     1321 aaacatatgt gcccatggct tctgcccggt ttgctcggtc tggctcggtg tgcgccagta
     1381 ccgcatactt acgcagccat cattgaggca ggattttatc cggaaggtac agatctccag
     1441 cttgttctta agataattga gaccgcgcga caggaaatcc gtctgatgga ctattccttc
     1501 acctcttggg aggtggtccg gttcgaacat tcagtgagta caaaattctc catgtcaaag
     1561 tgatcgtcag cgacgaccgc cacaccgagg tggacgcgtc agaatcgctg atcggacacg
     1621 tcgcaatcta cactctgact tataagccag cctgaagggg catgttggct ttgacgatca
     1681 ggcaaaaaac aacggcgaat aaagtcgtat gatgatcttc acatttatca tcatcagcgt
     1741 tcatattact caacctgtaa tcaacctctg gcgtttttct gtatccatca caaccatttc
     1801 cggtaaaggt aaaaaaggga tttgaacctt tccggagatg ataatgaagg taaatgcatg
     1861 gacaattttg cttatgtcgg cgcatctgac ggcctgtgcc gtccctggca cagaaaaata
     1921 tcagaccagc atggacagcg ttacggcaga aaaaataagc cggattatcc agtcggatgt
     1981 cattccttat aaaggcgaaa accatggaga agttatcagc cgcgtatcgt ctgcttttct
     2041 cggaacacct tatcaggcgg atacgctcat cggtgggccc ggcatccccg aagtccttgt
     2101 agcgaatttc aacggcgtgg actgctttac cctggctgat tacgttgaag ccctggcccg
     2161 cagcgataat cagaaatcgt ttctgcataa tcttgccagg actcgctacg ccgcgggcaa
     2221 agttgcttat ctcagccgcc ggcacttctt ctctgactgg ttcgccgcag caccgcgtaa
     2281 tgcacgggat gtaacgccgg atatcagccc tgattatgtc gttgttgaca agcagcttaa
     2341 ccataaacct gatggcggcg agtacattcc tggtctgggc atccatcctc gtaaaataaa
     2401 ttacattccc ggaagagcca tcaaccagca ggtcatgaac cacctaaaaa acggggatta
     2461 tatcggtgtc tactccccgc ttgacgggct ggacgtttca catgtgggta tcgtagttcg
     2521 ccatgatgaa caggtgtggt tcaggaacgc ctcctcattg gccgcaaaca gaaaagtggt
     2581 ggacacaccg tttatggaat acatgcattc cagactgggc atcgttgtgc tgcgggctga
     2641 atgataaagt cattaccgga gtcgccagct gataatagcc gtccgacata ggtattgaaa
     2701 ccctgtgtac tgtggggccg acacggaaaa ttgctgtaaa ttcgtggatt tagtaaatac
     2761 tagaagatat ttgtctggag cgggcgaagg gaatcgaggt atcgaagata atcagccgct
     2821 aaccatttgc ttcctaaagg atgatgaatc cttgtggtta cagttatggt tacacattaa
     2881 tttatctctg gtcaagtcct ctcgtgactc tggtcaagtc ctctcgtgac tctggaacga
     2941 gtaaccgaag tcctaacttt aagacagtgg ccccaatcgt ccagacttga aaggggccaa
     3001 ggggggagag gcaccgacct ttgtctatta gatacctaca gagatttttg tgagattttt
     3061 taatacaagg tcataaccta ccgccaccag cccccaccga ccgcaaagtg aagacctgta
     3121 agcaccagag caatagctat tgcgggcata ctgctgattg ttattatcta tcactccctg
     3181 tagagcatct ggcagaccaa gtggacacag aggacgagct caaacaactc ctgtaagctc
     3241 atggatgtac tccttatgtt cactcagggt ttatagttac tctggggtag taaaccgaat
     3301 aacatgtatc aacgggaaag aggcgtcttt ctcaacgtca aactcacctg ctttcacctt
     3361 aacggaacca gtagccaaca catcgaccac actgattaac tcaaggtcat acccagcagt
     3421 gttactattt cgggtcactt tgacatctac cgtcttagcg tctttagttg acctgaaaga
     3481 gatagaagcg aaccgcttag gcaggagata gacacctgta tcatcgcccg catagctgca
     3541 tacagtgcag cccaatagct cactaatatc ctcatgacct gcgcgttgag cggctcggtc
     3601 caagattgcc tcaagtctct cagggaccaa tacagcgtaa tcgctcagtg tatttcccaa
     3661 ctcgaccgga agattcaacg ctaatgtatc cagaagatct tcagcttgat cagacggttt
     3721 accacttagt ggggctgcct caatgatttg aaggtctggc gtatctttca ggacatcgac
     3781 cacagcggcg aacatctggc ggctgtattg aacctgcata tcacctacag tctggattaa
     3841 tgccccctcg gtccaaccgc ccatcatatc gaagtcagat acatgagtag cagcagaaca
     3901 caggatgccc gtcttattgg tctcagggtt caacactggg gtgacagtta cgcttgcccc
     3961 tttgatggct gtggtagacg gagcatcctt agctggatta aacgcgccat tatgcttaaa
     4021 gcggacggtg cgattctgga gagcctgacg gcgaataggc gtagggtcag tgccgtatgg
     4081 gcgaaactca caagggaaga cattctccat tacagcagtg cggaagtctc catcattgaa
     4141 ggtctcatcc aaagagtcct ccagcgcctg aacaaaatca tgtgaatcat tcccgaaggc
     4201 catcggacgg cctgagcggt ccgtaaagcc tacgttgaga acttgggcgt cttgaccatt
     4261 ggtcatctga acatagtcag tgcgtgagat gtcagtgccc catatagacc ccttaatgat
     4321 ttgaccgtct ttatctcgct gaggctgacg cagagaagcc agtgaggatg ctttgttaat
     4381 ttgatttgta atagacacga tgaatatctc cttattgtat gaatgcacta cgtaaaaagt
     4441 aactggtgac accattggtc ttatctcaga atccaagcag cgccaccgaa agttatcagt
     4501 tacagcccga aagcggcccc tttattgccg aagcgtttaa tcaatgcttc ctctcgggct
     4561 ttacgttcag cgaccgcctt agcaatctct tctggtgtcg catgaatagc agccatacgt
     4621 tcttgatgtg ccttagcttc tttacgtcgg cgttcagcct cttggcgctc ctgtgcgttg
     4681 ctttgagccc accagcggga atacttgccg taatcacctg catcaagacc agcggcgtga
     4741 atatcgttaa gaatacgatt tgagttcgcc atgtcagagc ctgtactgtt cagcatggtt
     4801 gtaacgacaa tttcggtgaa atacttagtg gatagctcct gaccgaatac cagtacagtt
     4861 tctttgtcag cgctcagtgc gatatccagt ttgcgataag aaatagacat gtttgtttct
     4921 cctttgaaaa gatgttttaa aaggattaaa ctcatcggtc ttccataggt attcctacgg
     4981 cgtctccccg tatcttggtc agttcaaaag gtggtgctag ctgtgctagt gggttaatta
     5041 catgaaatct cttggggtca gccctgcgtc aaccgccatg agacagaggg cagctttaga
     5101 gtaatacggg cggttttcct tggcaggcag acccagagta gctatcagtg ccttgggggg
     5161 taccaccatc aggcgtaacg ccttacggcc ttctggtgtc cttgggtcaa tcttgattgt
     5221 gtcatttgtg ttattagtca tgaattacct cccctccagc tttgctactg cctgtatgtg
     5281 ttgctgttta gcagcgtcgc ttccatgaac cgctatgacc tttctgtgca tcttgagtac
     5341 gttttcaggt cggctgaaga actccagccc cttagcgtta aaccgaatgt ttataccgtt
     5401 tgggttgaat cgatggtcag taggtttgat aattcgaaag tactccacat agtttggatt
     5461 gactgaccac tcgccactgc ttgaatgtac tcggaacagc ttgcgctctt tcttaaggat
     5521 ggtcatcagt ttctgagcgg gtagaccatt ggccttgcag taatcgcccc aagtcacgcc
     5581 tcgacgatta gctgactgaa tggctgctcg tttcttctgg tcttccagtt gaagaactcg
     5641 acgttctaac gtctgaatat ggtcgtaaca cttggcgcgt aggtgaacag aatagccagc
     5701 gaccagaata aaagtatgct tacggtcgag acggtacaga ggctgctgtt tcccctgcgc
     5761 atttagatag acatcttcaa tcacccctat aggactgctc agttttgagc agtgctcagt
     5821 tttgagtgcg ttaagctcct caaccatatt gcgaatatca cgaaggacat ttcggtgctc
     5881 cttgcctgtc agctcagcaa tttcaactga ggtcatggac acaagctggt cgaggttaat
     5941 gatgctgatt tcttgttgag acatagcttg atttcctttt tgtttgcacc ctgaagtcgc
     6001 acccccactg acctactcaa agtccccaag cgaagggaga ccagcaggac aacaggatgc
     6061 aaacagaatg actttgagat tgaatgaatg aatgacgatg attgtgtcgt agctgtgcgg
     6121 agctactgta tggtgaagcg cgagaggtgg aactttgaga gacacgtggt gagtggttcg
     6181 gagtgtgtct cctattagta agtcgtattg attcgtattg attcgtattg atttactact
     6241 gggagggtct ctcaagggtc tctgagccac gctaggcatc aggccatacg aaactacatg
     6301 gcatcctaaa gaatggagta caggaccata cagggccata cagttagctt ctggggtaat
     6361 gccttgagga gacctatagg tttggtgatt gattgttata aatatcatca cctc
//
LOCUS       DAJVKX010000187         6378 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.187, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000187 DAJVKX010000000
VERSION     DAJVKX010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6378
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.187"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(154..1059)
                     /locus_tag="OPY25_004183"
     CDS             complement(154..1059)
                     /locus_tag="OPY25_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0929644.1"
                     /translation="MDKLEAMQVYVCVVDTHSFIRAAEVLGVPRSTVSRVVKELESWL
                     KIQLLQRTTRKLSVTAEGRRYYEECKRVLADIAAMESSFPGRAAQPKGRFKVGMPQSL
                     ARHCIIPTLPAFLCQYPELELILCSSDSVEDIILQGYDCVIRAGRIDDSTTLVARPLA
                     SFNWVIAASPTYIERYGSPENLDDLQKHHAVGYLNHRTGRTTDWFFTREGEDYAMRVQ
                     ETLVVDDTDAYIQAGIQGLGLIRVASYLVAPYLHSGALVTCMDNHFYDLPLALVYPQN
                     RFLSPAVRAFYDWCKTALSQPEPLR"
     gene            1178..2107
                     /locus_tag="OPY25_004184"
     CDS             1178..2107
                     /locus_tag="OPY25_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic alcohol reductase"
                     /protein_id="HCS0929645.1"
                     /translation="MKQSNNQVGEKVLVLGAGQLGASVLASLVPAITQRNGSVCVIVS
                     GRSRDKQSKRRSSIHQQLADAGARFIPVDIADSSVAALKDQFHGFDTIINCMGFVAGA
                     GTQIKITRAVLEAGVKRYFPWQFGVNYDVVGKGSGQPVWDEQYDVRTLLREQNVTEWV
                     IVSTGLFTSFLFEPAFDVVNLDQKTINALGGWERQVTVTSPADIGRLTTEIYLHQPRI
                     TNEVVFVAGETTSYAKLAKTVERVTQQTFTRGVLTLPDLQEQLRLHPHDPMLRYRVAF
                     ARGDGMWWPMSDTWNAQHHLPTQDIATWLKTQQ"
     gene            complement(2204..3817)
                     /locus_tag="OPY25_004185"
                     /pseudo
     CDS             complement(2204..3817)
                     /locus_tag="OPY25_004185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460637.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
     gene            4007..4735
                     /gene="mpaA"
                     /locus_tag="OPY25_004186"
     CDS             4007..4735
                     /gene="mpaA"
                     /locus_tag="OPY25_004186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HCS0929646.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAVNRESGLI
                     LAGTHGDETSSVVTLSCALRTLNPSLRRHHVVLAVNPDGCQLGLRANANGIDLNRNFP
                     AANWKAGETVYRWNSRAQERDVVLLTGDHPGSEPETQALCQLIHRLQPAWVVSFHDPL
                     ACIEDPRRSELGEWLADAFALPLVTSVGYETPGSFGSWCADLNLHCITAEFPPVSADE
                     ASEKYLLAMSNLLRWHPKDGVDPS"
     gene            complement(4710..5675)
                     /gene="ycjG"
                     /locus_tag="OPY25_004187"
     CDS             complement(4710..5675)
                     /gene="ycjG"
                     /locus_tag="OPY25_004187"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HCS0929647.1"
                     /translation="MRSVKVYEETWPLHTPFVIARGSRSEAHVVVVELEEEGVKGIGE
                     CTPYPRYGESDASVMAQIMSIVPQLENGLTREALQKLLPAGAARNAVDSALWDLQARQ
                     RQQSLAGLLGVTPSPVFTTAQTVVIGTPEQMAASAAALWKKGATLLKIKLDARLISER
                     MVAIRSAVPEATLIVDANESWRPEGLAARCQLLADLNVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSSLKALTGRYDMINIKLDKTGGLTEALALATEAREQGFGLMLGCM
                     LCTSRAISAALPLMPQVSFADLDGPTWLAVDVEPALRFTTGQLHL"
     gene            5791..6297
                     /gene="tpx"
                     /locus_tag="OPY25_004188"
     CDS             5791..6297
                     /gene="tpx"
                     /locus_tag="OPY25_004188"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HCS0929648.1"
                     /translation="MSQTVHFQDNPVTVANVIPQAGSKAQAFTLVAKDLSDVSLSQYA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEVENTVVLCVSADLPFAQSRFCGAEGLSN
                     VITLSTLRNNEFLKNYGVEIVDGPLKGLAARAVIVLDENDNVIFSQLVDEITHEPDYD
                     AALNVLKA"
BASE COUNT         1495 a         1757 c         1584 g         1542 t
ORIGIN      
        1 ttgcatccaa acgttcagtg cttgctatat cctcgccgtg tagcacctgt ttgataatgc
       61 cttttactta tgcgtcaaaa accagtaccg tcattttgac cgtctgtgaa aaagttttct
      121 gaacaggcaa tgcgatatcc ggaataatat tttttagcga agaggctccg gctggctcag
      181 cgccgttttg caccagtcat aaaaagcgcg taccgcaggc gacagaaacc tgttttgcgg
      241 atagaccagc gcaagcggca aatcataaaa atggttgtcc atgcaggtca ccagcgcccc
      301 gctgtgcaga tacggcgcaa ccagatagct ggcgacgcga attaacccca gcccctgtat
      361 tccggcctga atataagcgt ccgtatcatc gacaaccagc gtctcctgca cccgcatcgc
      421 gtaatcctcc ccctcacgcg taaaaaacca gtcggtggta cgcccggtgc ggtggttcag
      481 gtagccgact gcatggtgtt tttgcagatc atctaaattt tcagggctac cgtaacgctc
      541 aatgtaagtg ggcgatgctg ctatcaccca gttaaagctg gcaagtggac gggcaaccag
      601 cgtggtggaa tcatcgattc tgccggcccg aatcacgcag tcataccctt gaaggataat
      661 atcctccacg ctatcgctgg aacaaagtat cagctccagc tccggatact ggcacaaaaa
      721 ggccgggagc gtaggaataa tgcaatgccg ggcgagagat tgcggcatcc ccactttaaa
      781 acgccctttg ggttgtgccg cccggccagg aaatgacgac tccatggccg cgatatctgc
      841 cagcactctt ttgcactctt cgtagtaacg ccgcccctct gcggtcacgc taagtttgcg
      901 ggttgtacgt tgcaaaagtt gaatcttaag ccaggattcc agttctttaa ccactcgcga
      961 taccgttgag cgcggcacgc caagcacttc ggcggctctg ataaaactat gggtatccac
     1021 tacgcaaaca tagacctgca tcgcttccag cttgtccatt ttccccccgc caattatccc
     1081 atttatcaga acagtctaac ccgtcttcgg cgtcttatcg aacgcagatc cctgacgtaa
     1141 tctctatcta caggtgaatc aacacagaga ggcgcaaatg aaacaatcca ataatcaggt
     1201 gggtgaaaaa gtattggtgc tgggcgcggg acaactgggg gcgtcagtgc tggcgtcgtt
     1261 ggttccggcg atcacacagc gtaatggttc cgtttgcgtt attgtgtcag ggcgatccag
     1321 ggataaacag agcaaacgac gttccagcat tcatcaacaa ctggcggatg ccggtgcgcg
     1381 gtttatcccg gtcgacatcg cagacagttc ggttgcagcg ttaaaagatc aattccacgg
     1441 ttttgatacg atcatcaatt gtatggggtt tgtcgccggt gcgggtaccc agataaaaat
     1501 cacccgcgcg gtactggagg cgggcgttaa gcgctatttc ccctggcagt ttggcgtgaa
     1561 ttacgatgtg gtcggcaaag gcagcggcca gccggtgtgg gacgaacagt atgacgtcag
     1621 gacgcttttg cgcgagcaaa acgtcacaga gtgggtgatt gtttcaaccg gtttatttac
     1681 ctcttttctc ttcgaaccgg cctttgatgt ggtcaactta gaccaaaaaa ccatcaatgc
     1741 cctcggcgga tgggaaaggc aggtcaccgt cacgtcgcct gcggatattg gtcgcctgac
     1801 cactgaaatt tatctgcatc agccgcgtat cactaacgaa gtcgtctttg ttgcggggga
     1861 aacgacctct tatgcaaaac tggcgaaaac ggtcgaacgc gtgacgcagc aaacctttac
     1921 ccgaggtgta ttgacgctac ctgacttaca ggagcaactc cgtttacatc cgcatgaccc
     1981 aatgctgcgc tatcgcgtcg ccttcgcgcg tggtgacggt atgtggtggc cgatgagtga
     2041 cacctggaat gcacaacatc atctgccgac acaggatatt gccacctggc tgaaaacaca
     2101 gcaatgagaa cggcggcatc aggcgctcgc ttaatcccca tgccttctgc cagcatcagg
     2161 cggcgggcgt ggctaccttg agttaacaag aaaccagtac gcatcagtgc ttcacgatat
     2221 acattgtacg gctataggcc acatcttccg ggttagtaat ggggtatccc tttacccacg
     2281 gtttaattaa ccggccattg gtatactgat aaataggtgc tataggcgct tgttccgtta
     2341 aaattttctc cgctgcattg taatccgcgt tacgcgcttc ggcggtattt tccatcgtcg
     2401 cttgcgtcag gattttgtca taagtcggat tagtaaagcg tgaaatattc cccgtatgcg
     2461 tggacgttaa taaggataag aaagtcgacg gttcgttgta atcacccacc caggagacgc
     2521 gaataacatc aaaattactg gtattccggc tgtcgatata cgttttccac tcctggtttt
     2581 gcaatttcac atccaccccc agatttttct tccacattga cgccaccgca atcgcgattt
     2641 tctgatggtt ttctgaggta ttgtaaagca gagttaattt aagcggcttc tgcgatccgt
     2701 agcctgctgc acgcagcaat gttttcgcct gggcgttaag ttcttcctga ctcatttgtt
     2761 caaacggtga aggatcgggc ttaaatcctg ccgtgacatc cggtgtaaaa tgccaggccg
     2821 gtttttcacc ggtacctaag actttttccg ccatcaaacg gcgatcaatg gtcatactta
     2881 gcgccagacg aacgcgggaa tccgccgtcg gccctttctg cgtattaaac gcataataat
     2941 aagtccctaa ttgcggcggc gtataaactt gccctggaat atccttcaat aatttctggt
     3001 acatattttt agggaaagat tcggtgatat caatatcacc ggcaagatag cgtttcgtcg
     3061 cagccgactc ctggttaatg ggtaaaaatg tcactttttg cagtaccgtt ttcgcgttat
     3121 cccagtaatg cgtattaggc acgaccacca gtttttcatt taccacgcgc tctttaagca
     3181 catacgcgcc attgccaatc agttttcccg gcttcatcca gtctttgccg ctttcgacat
     3241 tcgctttttg gaccggataa aaggcaaaac tggcggtcag actggcaaac cagggcaacg
     3301 gcttgtcaag ctgaacacgc aaagtgtgcg cgtccacggc actgacgcca agctgatccg
     3361 gcgtgacttt actgtcgata atggcttgcg cattagtgat gccagccaga gcggcaaacc
     3421 aggcgaaggg ggaaagcgtt ttgggatcaa cgaggcgttg ccagctatag acaaaatcct
     3481 gggcggtcac cggcgttcca tcggcccatt gcgcatcatc ccgcaacgta aacgtccaga
     3541 tacgattatc attgctcttt cactggctgg cgacgccagg gataatttca cccttttcgt
     3601 tctggttaac cagcccttca aacagatcgc ggatcacctg aatttcaggc agcccaacgg
     3661 ctttcgctgg atctaacgaa gcgggctcat ctttgatatg acgcaccagt tcttgtttct
     3721 ctgccagtac cgttccgccg ggaacatccg cagcatatgc cagggaaaag ctgctaacca
     3781 acagcgcaca acaggttact gaaacagaat gcctcataga agttcctcaa agatgagtta
     3841 aatgacaacg taattatttg tttcagcaga aagaaatgca attatcttcc gccagaaagt
     3901 tgatatcgcg ccatacaaga gggtaaatag aaaccatttg ataatcggcg ggttttacac
     3961 aacactacga tgattaccct actggtctca gcttcgggaa acgcgtatga ctgtcacccg
     4021 cccccgtgcc gagcgcggcg catttccgcc aggcactgaa cattatggac gttcgctact
     4081 aggcgcgccg ctaatctggt ttccggcgcc tgccgtcaat cgcgaaagcg gcctgatact
     4141 ggctggcacc cacggggatg aaacctcatc cgtggtgacg ctctcctgtg cgttacgcac
     4201 cttaaatccg tcccttcgcc gtcatcatgt cgtacttgcc gttaatcctg atggctgtca
     4261 actggggtta agggcaaatg cgaatggcat tgatctaaac cgtaactttc ccgccgccaa
     4321 ctggaaagcg ggtgagacag tttatcgctg gaatagccgc gcgcaagagc gtgatgtcgt
     4381 gctgctaacc ggcgaccatc ccggctcaga accggaaacc caggcgcttt gccagttaat
     4441 tcatcgactc caacccgcct gggtcgtctc ttttcacgat ccgctagcct gcattgaaga
     4501 tccacgtcgc agcgagctag gcgagtggct ggccgatgcg tttgcgttgc cgctggtgac
     4561 cagcgtaggt tacgaaacgc ccggttcgtt tggcagctgg tgcgccgacc tcaacctgca
     4621 ctgcattacc gccgagtttc cccctgtttc cgccgatgaa gccagcgaaa aatacttgct
     4681 ggcgatgtcg aatctgctcc gctggcatcc taaagatgga gttgacccgt cgtaaagcgt
     4741 agcgcaggct caacatcaac cgccagccat gttgggccat caagatcggc gaagctcacc
     4801 tgcggcataa gcggcagcgc ggcgctaatc gctcttgatg tacagagcat acagcccagc
     4861 atcaggccga atccttgctc ccgcgcctcc gttgccagcg ccagcgcctc agtcagaccg
     4921 ccggttttat ccagcttaat gttgatcata tcgtagcgcc ccgtcagggc tttcagacta
     4981 ctgcgagtat ggcagctctc atctgcacag atgggcaacg gatgaataaa attttccagg
     5041 gcggcgtcat cctgcgcggg cagcggttgc tccagcatcg cgacattcag atccgccagt
     5101 aactggcaac gcgccgccag cccttctggg cgccacgatt cattggcgtc cacaatgagc
     5161 gtcgcctccg gcaccgccga gcggatcgcc accatacgtt cgctaatcag acgagcatcg
     5221 agtttaattt tcagcaacgt cgcccctttt ttccatagtg ccgccgcact ggcagccatc
     5281 tgttccggcg tgcctatcac taccgtttgc gcggtagtaa aaaccgggga cggcgtcacg
     5341 ccgagcagcc cggcaaggct ttgctgccgc tggcgggcct gcaaatccca taaggcgcta
     5401 tccaccgcgt tgcgcgccgc gcctgccggc aacagtttct gcaatgcttc gcgagtcagc
     5461 ccgttttcca actgaggcac aatactcatg atttgcgcca tgaccgaggc atcactttca
     5521 ccataacgtg gatatggcgt acattccccg atgcctttta cgccctcttc ttccagttcg
     5581 acaacgacaa catgcgcttc gcttcggcta ccacgcgcaa taacaaaagg cgtatgtaac
     5641 ggccaggttt cctcatatac cttaacagat ctcatctctt cccctctgat agcgccggac
     5701 gcggcttgct acaaatagta tttgccgtgt taatgaataa tgacttaaac tggatttcga
     5761 cgttaactat aagtaaatag gaacataatt atgtcacaga ctgtacattt ccaggataac
     5821 ccggtcaccg ttgccaacgt tattccgcag gctggtagca aagcacaggc ttttactctt
     5881 gtcgcaaaag atttgtctga cgtttccctc agccaatatg caggcaaacg caaagtgctg
     5941 aatattttcc caagcattga tactggcgta tgcgccgcat cagttcgtaa gtttaatcaa
     6001 ctggccacag aagtggagaa taccgtcgta ttgtgcgttt ctgctgacct gccttttgca
     6061 cagtcgcgtt tttgcggcgc ggaaggcctg agcaacgtta ttacgctttc cactctgcgt
     6121 aataacgagt ttctaaaaaa ctacggcgtc gaaatcgttg acggcccgct gaaaggtttg
     6181 gcggcgcgcg cagtcatcgt gcttgacgaa aacgacaacg ttattttcag ccagttggtg
     6241 gatgaaatca cccacgagcc ggattacgac gccgcgctta atgtcctgaa ggcataagcc
     6301 agcgcctgct ggcgctacgt ttgtcagtgc tacaggcggt gctcttttgt cacaagaagg
     6361 cctctatccg gaggcctt
//
LOCUS       DAJVKX010000188         6361 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.188, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000188 DAJVKX010000000
VERSION     DAJVKX010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6361
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.188"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..370)
                     /locus_tag="OPY25_004189"
     CDS             complement(<1..370)
                     /locus_tag="OPY25_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001171576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929649.1"
                     /translation="MQKPILSLNSTCIVGGILWLLPVIVVHADEIVCPAVIHFSQAPI
                     ISSAEGWNVSSRAARMLNDGGFLSSGDPKEQADLKGEDAVVDGKKGHLWEIDPEDNRR
                     GIWFSCSYGQWAVLLARKVQG"
     gene            complement(342..743)
                     /locus_tag="OPY25_004190"
     CDS             complement(342..743)
                     /locus_tag="OPY25_004190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001147173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BPSL0067 family protein"
                     /protein_id="HCS0929650.1"
                     /translation="MPYVYANAKALQDTEKVGNHHQCVELIQHYIRVGQASTWQQGAA
                     VFGNKNIEVGTVIATFVNGRYPNHNSGNHAAFFLGQDTGGIWVMDQWKDDIAKPRVSK
                     RYIRKLHNGSVRSDGTYIRMSNNAEAYFIVE"
     gene            complement(796..2304)
                     /gene="tssC"
                     /locus_tag="OPY25_004191"
                     /pseudo
     CDS             complement(796..2304)
                     /gene="tssC"
                     /locus_tag="OPY25_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459271.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
     gene            complement(2328..2870)
                     /gene="tssB"
                     /locus_tag="OPY25_004192"
     CDS             complement(2328..2870)
                     /gene="tssB"
                     /locus_tag="OPY25_004192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HCS0929651.1"
                     /translation="MAINNSAQKFIARNRAPRVQIEYDVEIYGSEKKIELPFVMAVLA
                     DLAGKPREELPPVTDRKFLDIDIDNFNERMKAIAPRVAFAVPNTLTGEGQLMVDITLE
                     NMDDFSPAQIARKVDALNQLLEARTQLANLQTYMDGKAGAENLVNKLLQDPTLLKTLA
                     NAPKSAATQQGVSADNESAE"
     gene            complement(2934..3224)
                     /locus_tag="OPY25_004193"
     CDS             complement(2934..3224)
                     /locus_tag="OPY25_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929652.1"
                     /translation="MTLRDPALLTPLLMMFAFSVHGEPPLPQDVQHFLSNAEMCQHLA
                     GEWDSSLPEEDKKDIKKGINTWCPPAKKALPGLREKYKENKEIIKKLSEYDF"
     gene            complement(3310..5973)
                     /gene="tssH"
                     /locus_tag="OPY25_004194"
     CDS             complement(3310..5973)
                     /gene="tssH"
                     /locus_tag="OPY25_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HCS0929653.1"
                     /translation="METPVSRSALYGKLAGPLFRSLESATAFCKLRSNPWGELTHWLH
                     QLTQQPDNDILHVLRHYQIPLSDVEKALLRQLDMLPAGASAISDFSHHIDLSVEKAWM
                     LASVRYGDNKIRSGWLLLALLTTPELRRVLSSICAPLATLPVDELTEILPSLIETSPE
                     AQERPYDGSGLASAIPGESSQAIPNGVQDGKSALAKYCQDMTAQARDGKIDPVTGREH
                     EIRTMTDILLRRRQNNPLLTGEAGVGKTAVVEGFALAIAQGEVPPALREVRLLALDVG
                     ALLAGASMKGEFESRLKGLLEEAGRSPQPVILFVDEVHTLVGAGGASGTGDAANLLKP
                     ALACGTLRTIGATTWSEYKRHIEKDPALTRRFQVLQIAEPEEIPAMEMVRGLVDTLEK
                     HHNVLILDEAVRAAVQLSHRYIPARQLPDKAISLLDTAAVRVALTLHTPPASVQFLRQ
                     QLKAAEMERSLLQKQEKMGIQSDERCDALTARIFSLNDELTASESRWQRELELVHTLQ
                     ELRVAESDADDKTTLQQAETALREWQGDAPVVFPEVSAAIVAAIVADWTGIPAGRMVK
                     DEASQVLELPARLAQRVTGQDGALAQIGERIQTARAGLGDPRKPVGVFMLAGPSGVGK
                     TETALALAEAIYGGEQNLVTINMSEFQEAHTVSTLKGAPPGYVGYGEGGVLTEAVRRH
                     PWSVVLLDEIEKAHHDVHELFYQVFDKGGMEDGEGTHVDFKNTTLLLTTNVGSDLISQ
                     MCEDPALMPDATGLKEALMPELRKHFPAAFLGRVTVIPYLPLDETSRGVIARLHLDRL
                     VARMGEQHGVTLTYSEELVAHIVACCPMHETGARLLIGYIEQHILPQLSRYWLQAMTE
                     KAAIRQIDIGVNGDEQIVFETTSQEGICQKS"
BASE COUNT         1458 a         1798 c         1556 g         1549 t
ORIGIN      
        1 ttccctgaac ttttctggca agcagaacag cccactgtcc ataactacac gagaaccaga
       61 tcccccggcg attatcctct gggtctatct cccacaggtg cccctttttc ccatcaacga
      121 ctgcatcttc acctttcaga tctgcctgct ctttgggatc gccagacgaa agaaaaccac
      181 catcattcaa catacgcgct gcacgggatg agacattcca tccttccgct gaggaaatta
      241 ttggagcctg agaaaaatga ataaccgcag ggcagacaat ctcatcggca tgaacaacta
      301 ttaccggaag taaccacaga atgcccccga caatacaggt gctattcaac gataaaatag
      361 gcttctgcat tattactcat ccttatataa gtcccgtcac tacgaacact tccattatgc
      421 aactttctta tataacgttt ggacacacgg ggttttgcga tatcatcttt ccattgatcc
      481 atcacccata tcccgccagt atcttgcccc aaaaaaaatg cagcatggtt gccactattg
      541 tggttcggat atcgcccatt cacaaaagta gcgataactg tcccgacttc aatgtttttg
      601 tttccaaata ctgcggcccc ttgctgccat gtactcgctt gtcctactcg tatatagtgt
      661 tgaataagtt caacacactg atggtggttt cctacctttt ctgtatcctg taaagccttt
      721 gcattagcat aaacatatgg catatattct cttaatatcc tctgatatta tttatacatt
      781 cacaaaataa atgcatcagg cattgccctg cttcactgac ggcagttttg tcaccaggcg
      841 cagcgatcct gtcagccctt caagctggaa atgcggacgc aggaagaatt tcgcgtcgta
      901 ataacctgga ttgccttcca cctcttccac cactacctcc gcggcagcca gcggacgacg
      961 ggctttggtt tcttgcgagg agttcaccgg atcggcgtcg acataattca taatccattc
     1021 atttagccag cgctgcatat cctcgcgctc tttaaaggaa ccgattttgt cgcggacgat
     1081 acatttgagg aagtgcgcga agcgcgagca ggcgaacagg tacggcagac gggcggacag
     1141 gttagcgtta gccgtcgcgt ccggatcgta gtattcctgt ggtttttgca gcgattgtgc
     1201 gccgataaag gcggcatagt ctgagttttt acggtggatc aacgggataa aaccgttttt
     1261 cgccagttca gcctcgcggc ggtcagagat ggcgatttcg gtcgggcatt tcatgtccac
     1321 gccgccatcg tcagtcggga aggtatggca gggaagattt tccaccgcac cgcctgattc
     1381 cacaccgcga atcaacgtac accagccgta gtgtttgaag gaacggttga tgtttacgcc
     1441 catcgcgtag gccgcgttgc tccagacgta tttggtatgg tcagaaccat ccgcatcttc
     1501 ttcaaaatca aactcgtcca ccgggttggt ttttgcgcca tacggcaggc gggcaagaaa
     1561 acgcggcatc gtcaggccaa tataacggga gtcttcgcta gcccgcagcg agttccacgg
     1621 cgcatattcc aggttctggg tgacgatttt ggtcaggtcg cggggattcg ccagctcctg
     1681 ccaggagtcc atttgcagta ccgaggggga agccccggca ataaacggcg catgggccga
     1741 cgcggcgact ttggcgatag agccaagcag atccacatcg ggcggtgtat ggtcgaagta
     1801 gtaatccgca atgatacagc cataaggttc gccgcctaac tggccgtatt cggcttcata
     1861 cagtttcttg aacatcgggc tttgatccca ggcggtgccc ttgtaacgct tcatgttgcg
     1921 ccgcaattca tcttttgaca gattcatgaa gcgaattttc agcttttcgt cggtctcggt
     1981 gttgtaaacc agatgctcca taccgcgcca cgaggattcc agcttctgcc agtcgggatg
     2041 ttgcaggatc agtttgatct gttcggtcag tttaaagtcg atctgcgcaa taatagcgct
     2101 gatgctttta taggcgtcat cgctgacggt gatcgtgttc gccagcgcct gttgcgccag
     2161 cgtctacacc gcggcttcca cagcttttgc cgcctgggta gtcttgggtc ggaaggcctg
     2221 attcagcaac gcatcaaatt caccggatgc ggagacggta tcctgagcaa ccgcgtcggt
     2281 tgcctgcata ttactgtttg ccatgaaaat tccttaaaaa ttcgacatta ttccgctgat
     2341 tcattatccg ctgacacacc ttgctgggta gcggccgatt tcggcgcatt cgccagcgtt
     2401 ttcagcagag tcgggtcctg caacagttta ttgaccagat tttccgcccc ggccttgcca
     2461 tccatgtagg tctggaggtt cgccagttga gtgcgggctt ccagtaactg gttcagggcg
     2521 tccaccttgc gggcaatctg tgccggcgaa aagtcgtcca tattttccag ggtgatatcg
     2581 accatcaact gaccttcacc cgtcagcgta ttcggcacag cgaacgccac gcgcggcgca
     2641 atggctttca tgcgctcatt gaagttatca atatcaatat cgaggaattt gcgatccgtc
     2701 accggcggca gttcttcacg cggtttcccg gccagatcgg ccagcaccgc catcacgaac
     2761 ggcagctcga tttttttctc ggaaccgtaa atctctacgt catattcaat ctgcacgcgc
     2821 ggcgcgcggt tgcgcgcgat gaatttctgc gcgctattgt tgatagccat aatccttcat
     2881 ttccttttta gtcaactggt tgccgcaagg ggagcggtat accggtacag tttttaaaaa
     2941 tcatactcag agagtttttt tataatctct ttgttttctt tgtacttttc ccgtaaccca
     3001 ggaagtgctt ttttcgccgg agggcaccag gtattaatgc ccttttttat gtctttttta
     3061 tcctcttccg gtaaagaact gtcccattcg ccggccagat gctggcacat ctctgcattg
     3121 ctcagaaaat gctgcacatc ctgtggtaaa ggcggttcgc catgaacact gaaagcgaac
     3181 atcattagca aaggagtcaa taacgccggg tcacgtaatg tcatatttaa tgcccatcaa
     3241 ttgaccagtg gggtttatct gtatttccgc cgacaaactt agtcacgcca taaacccact
     3301 gcgcaccact taactctttt ggcatattcc ctcctgcgag gttgtctcaa aaacaatctg
     3361 ctcatcacca ttaacgccga tatcaatctg cctgatagcg gctttttccg tcatggcctg
     3421 caaccagtag cgcgacagtt gtggcaggat gtgctgttcg atgtagccaa tcagcaaccg
     3481 cgcgcccgtt tcatgcattg gacagcacgc cacaatatgt gcgaccagtt cctcactata
     3541 cgtcagcgtc accccgtgct gttcacccat ccgcgccacc agccggtcaa gatgcagacg
     3601 ggcaatcacg ccacgcgacg tttcatccag cggcaggtaa gggatcaccg tcacgcggcc
     3661 cagaaatgcc gccgggaaat gcttgcgcaa ttccggcatt agcgcctctt taagccccgt
     3721 agcatcgggc attaaggccg gatcttcaca catctggctg atgaggtcgg aacctacatt
     3781 ggtggtgagt agtagcgtgg tgtttttgaa atcgacatgt gttccctcac cgtcctccat
     3841 cccgcccttg tcaaacacct gatagaagag ttcatggacg tcatggtgcg ctttttcgat
     3901 ctcgtcgagc agcactacgc tccaggggtg acgacgcacc gcttccgtca gcacaccacc
     3961 ctcgccatag cccacatagc cgggcggcgc gcctttcagt gtggaaacgg tgtgagcctc
     4021 ctggaactcg ctcatattga tggttaccag gttctgctca ccgccgtaga tagcctccgc
     4081 cagcgccagc gcggtttcgg ttttaccgac accggacggc ccggccagca taaacacgcc
     4141 caccggtttg cgtggatcgc ccagtcccgc cctggcggtc tgaatacgtt caccaatctg
     4201 cgccagcgcg ccgtcttgcc cggtaacgcg ttgcgccagt cgggcaggca gttccagcac
     4261 ctggctggcc tcatctttca ccatgcgccc ggcaggaata ccggtccagt cggcgacaat
     4321 cgccgcgaca atcgccgcgc tgacttccgg gaacaccacc ggcgcgtcgc cctgccactc
     4381 ccttagcgct gtttcggcct gttgcagcgt ggttttgtca tcagcatcag actctgcgac
     4441 acgcagttcc tgcaacgtat gtaccagttc cagctcccgc tgccagcggg attcggatgc
     4501 agtcagttca tcgttgagcg agaaaattcg cgccgtcagc gcatcgcacc gctcatctga
     4561 ctgaatcccc attttttcct gcttctgcaa cagcgaccgt tccatttccg ccgcttttag
     4621 ctgctgacgc aggaactgta cgctggcagg cggcgtgtgc agcgtcagcg ccacgcggac
     4681 cgcggcggta tccagtaggc tgatggcctt atccggcaac tgccgggcgg gaatgtagcg
     4741 gtgagaaagc tgtaccgccg cacgtaccgc ctcatccaga atcagtacgt tatggtgttt
     4801 ttccagcgta tccaccagac cacgcaccat ttccattgcg gggatctctt ccggctcggc
     4861 aatctgcaac acctgaaaac gacgggtcag cgccggatct ttctcaatat ggcgcttgta
     4921 ttcgctccag gtggtggcgc cgatagtccg cagggtgccg cacgccagcg ccggtttcag
     4981 caggttagcg gcatcgcccg tgccggatgc gccgcccgcg cccaccagag tgtgaacttc
     5041 atcgacaaac agaataaccg gctgcggcga gcgcccggcc tcttccagta accctttcag
     5101 acgcgattca aactcgcctt tcatgctggc tccggccaac agagcgccaa cgtccagcgc
     5161 cagcagccgt acttcccgca gcgcgggcgg cacttccccc tgcgcaatcg cgagggcaaa
     5221 accttcgacg accgccgtct ttccgacgcc cgcctcacca gtcagtaggg gattattctg
     5281 gcgacggcgc agcagaatat ccgtcatggt gcggatttca tgctcacgcc ccgtcaccgg
     5341 gtcgattttg ccgtcgcgcg cctgtgccgt catgtcctga cagtattttg ccagcgcgga
     5401 tttaccgtcc tgcacgccgt tgggaatcgc ctggctgctt tcaccgggaa tggctgatgc
     5461 cagaccggag ccgtcgtaag ggcgctcctg cgcttccggc gatgtttcga tcaacgaggg
     5521 cagtatttcc gtcagttcat caaccggaag cgtggccagc ggcgcgcaga tactgctcag
     5581 tacccgacgc agttctggcg tggtcaacaa ggccagcagc aaccagccgc tgcgaatttt
     5641 gttatcgccg taacggacgc tcgccagcat ccaggccttt tcaacgctga gatcgatatg
     5701 gtgagaaaaa tcactaatgg cgctggcccc ggcgggcagc atatccagtt gccggagtaa
     5761 cgctttctcc acatcagaaa gagggatctg gtaatgccga agaacgtgga gaatatcgtt
     5821 atcgggctgc tgtgttaact ggtgcagcca gtgagtcagc tcaccccagg gattagagcg
     5881 tagtttgcaa aatgccgttg ccgattccag cgaccggaat agtgggccgg ccagttttcc
     5941 atataacgca ctgcgtgaaa caggagtttc catttgttat gccttgtgac ataaaaattc
     6001 ataaaaataa tgcatcaatg cacatgaata tataaacaat tctttattaa aatgttcgac
     6061 aaaatatcga aacaaaacaa tgatacagat cagggactaa ttagcaacca agccgttaat
     6121 attaaataat caatgaacaa caagataaaa atcgcaatta cagaattaaa agaaataata
     6181 tttcaaaaaa gacatctatg catacaacaa tgcattcacg acgaaaataa taaaaagggt
     6241 gtcatcaata atgactccct atgaatttag ttaaaattat ttatgaatta aaactcccta
     6301 aacgtttcct ccagaaaaat aaatacattt aagggacata atgaaacaag acatgtggga
     6361 a
//
LOCUS       DAJVKX010000189         6301 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.189, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000189 DAJVKX010000000
VERSION     DAJVKX010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6301
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.189"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(222..2795)
                     /gene="clpB"
                     /locus_tag="OPY25_004195"
     CDS             complement(222..2795)
                     /gene="clpB"
                     /locus_tag="OPY25_004195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCS0929654.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SIRPLLTSAGINAGQLRTAIDQALSRLPQVEGTGGDVQPSSELVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLTDLLKSAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTVDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELDD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQSEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMLEGEREKLLRMEQEL
                     HSRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYGRMKEM
                     VLGVVSQNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHISDE
                     ALKLLSANGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEANDDRIVAV
                     Q"
     gene            complement(2925..3656)
                     /gene="pgeF"
                     /locus_tag="OPY25_004196"
     CDS             complement(2925..3656)
                     /gene="pgeF"
                     /locus_tag="OPY25_004196"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HCS0929655.1"
                     /translation="MNALIVPQWPLPKGVAACSSTRIGGVSLSPYDSLNLGAHCGDNP
                     EHVEENRKRLFAAGNLPSKPVWLEQVHGKNVLRLTGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNREGTEVAAAHAGWRGLCEGVLEETVTCFADKPENIIAWLGPAIGPA
                     AFEVGPEVRDAFLAKDAQADSAFLPHGEKFLADIYQLARQRLANTGVEHVYGGDRCTF
                     SESETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3653..4633)
                     /gene="rluD"
                     /locus_tag="OPY25_004197"
     CDS             complement(3653..4633)
                     /gene="rluD"
                     /locus_tag="OPY25_004197"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HCS0929656.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILNQR
                     VLVNGQLCDKPKEKVLGGERVAIDAEIDEEIRFEAQDIPLDIVYEDDDILVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQLREITREYEAVAIGHMTAGGTVNEPISRHPTKRTHMSVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDQVYGGRPRPPKGASEEFISTLRKFDR
                     QALHATMLRLYHPVSGIEMEWHAPIPQDMVDLIDAMRADFEDHKDDVDWL"
     gene            4765..5502
                     /gene="bamD"
                     /locus_tag="OPY25_004198"
     CDS             4765..5502
                     /gene="bamD"
                     /locus_tag="OPY25_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HCS0929657.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWKQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFMRLNPTH
                     PNIDYVMYMRGLTNMALDDSVLQGFFGVDRSDRDPQHARAAFNDFSKLVRSYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTARGAWVAVVNRVEGMLRNYPDTQATRDALPLM
                     ENAYRQMQLNAQADKVAKIIAANSKNT"
     gene            5774..6112
                     /gene="raiA"
                     /locus_tag="OPY25_004199"
     CDS             5774..6112
                     /gene="raiA"
                     /locus_tag="OPY25_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCS0929658.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFIADATINTPNGHLVASAKHEDMYTAINELINKLERQLNKVQHKGEARRATASVK
                     DASFVEAEEE"
     misc_feature    6215..>6301
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            6216..6263
                     /gene="pheL"
                     /locus_tag="OPY25_004200"
     CDS             6216..6263
                     /gene="pheL"
                     /locus_tag="OPY25_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HCS0929659.1"
                     /translation="MKLTRFFFAFFFIFP"
BASE COUNT         1531 a         1743 c         1496 g         1531 t
ORIGIN      
        1 cagacttctt aacgaagtct tcctgacccg gcggcctgta tgccgttgtt ccgtgtcagt
       61 ggtggcgcat tatagggagt tattagagcc tgacaagacc taaatgcaaa aaaaagctca
      121 accgttcact tttcaaacaa catttgaatc aaaagcctat ttttgcctgg tttttaaaca
      181 aaaacgagcc cgttagggcc cgttttattc aaatttgtga cttactgcac tgccacaata
      241 cgatcatcat tggcttcaag gcgaatcact ttgccaggaa ccagttcacc agacaggatt
      301 tgctgcgcca gtgggttttc gatctgctgt tgaatagcac gttttaacgg acgcgccccg
      361 tagaccggat cgtaaccgtt ggcgctcaac agtttcagcg cctcgtcgga gatatggatt
      421 tcataaccac gttcttccag acgtttgtac agacgctgca gctggatctg agcaatagaa
      481 gcgatgtgtt gctcacctaa cggatggaat accacaactt catcaatacg gttgataaat
      541 tccggacgga agttttggct aaccacaccc agcaccatct ctttcattcg accgtaatcc
      601 agttcgccaa agcgctcctg aatgagatcg gaaccgaggt tagaagtcat aatgaccacc
      661 gtattacgga agtcgaccgt tctcccctgc ccgtcagtca gtcgaccgtc gtccagcacc
      721 tgcaacagaa tgttgaatac atccggatgc gctttttcca cttcatccaa caagatgacg
      781 gaataagggc gacggcgcac cgcttccgtc aaataaccgc cttcttcata gccgacatat
      841 cctggaggcg ccccgaccaa acgagacacg gagtgtttct ccataaactc agacatgtcg
      901 atacgcacca tcgcgtcgtc gctgtcgaac ataaagttag ccagcgcttt acacagttcg
      961 gttttaccga ccccggtcgg cccaaggaac aggaaggaac caatcggacg gttcggatcg
     1021 gacagccccg cgcggctacg gcgtatggcg ttcgatactg cttcaacggc ttcattctgc
     1081 ccgatcacac ggctgtgtaa ctcttgttcc atacgcaaca gtttttcacg ttcgccttcc
     1141 agcattctgg aaaccggaat accggtccag cgcgccagca cttcggcaat ttccgcatcc
     1201 gttactttgt tacgtaacag acgcatggtt ttaccttccg actgggtcgc ggcttccagc
     1261 tgtttttcca gctccggaat tttgccgtac tgcagttcag acattcgcgc gaggtcgcca
     1321 acgcgacgcg cctgctcgat ggcgatcttc gcctgctcca gctccgcttt aatagtttgc
     1381 gtaccagaga gcgacgcttt ttccgctttc cactcttctt ctaactcaga gtactgacgc
     1441 tctttatcgt ccagttcttc attcagcata tcgagacgtt ttttactcgc ctcgtcagac
     1501 tctttcatca acgcctgctg ttccagtttg agctgaataa tgcggcggtc gagcctgtcc
     1561 agctcctccg gcttcgagtc aatctgcata cgaatgctgg atgccgcttc atcgatgagg
     1621 tcgatagctt tatccggtaa ctgacggtcg gcgatatagc ggtgagataa tgttgccgcc
     1681 gccacaatcg ccgggtcagt gatctgcaca tggtgatgca gttcataacg ctctttcaga
     1741 ccacgcaaaa tcgcaatggt gtcttccacc gacggctctg ccacgaacac tttctggaat
     1801 cgacgttcca gcgccgcgtc tttttcgatg tactgacgat attcgtccag cgtggtggcg
     1861 cccacacagt gcagttcccc acgtgccagc gccggtttca gcatgttacc ggcatccatg
     1921 gcgccatcag ctttacctgc gccaaccatg gtgtgcagct cgtcgataaa caggatgacg
     1981 ttgccttcct gttttgcgag gtcgttcagc acgcctttca gacgctcttc aaattcgccg
     2041 cgatatttcg ccccggccac cagcgcgccc atatccagcg ccagcacgcg acggcctttc
     2101 aggccttccg gtacttcacc gttgataata cgttgcgcca gcccttcaac aatggcggtt
     2161 ttacctacgc ctggctcacc gattaacacc gggttgtttt tagtacgacg ttgcaatacc
     2221 tgaatggtac ggcgaatttc ttcatcacga ccaattaccg ggtcaagctt accttgttca
     2281 gcccgctcgg tcagatcgac ggtatatttt ttcaaggcct gacgttggtc ttcagcccct
     2341 tgatcgttca cgctttcacc tccgcgcatc tgttcaattg cctgagtgat attggccgta
     2401 gtcgcaccgg ctgatttcag cagatcggtt aacgtgccgc gagactcaag cgccgccaga
     2461 acaaacagct ctgacgaaat aaaattgtcc ccccgttttt gcgccagctt gtcgcaaagg
     2521 ttcagtacgc gtaccagttc cgaagaaggc tgtacgtcgc cgccggtgcc ttccacctgc
     2581 ggtaaacggc tcagcgcctg atcgatagca gtgcgcaact ggccagcatt aatgccggcg
     2641 gaggttaata aaggacgtat cgatccccct tcctggttca gcaaggcgct cattaaatga
     2701 agaggttcga tgaattggtt gtcgtgcccc agcgcgagcg actgggcatc ggcaagagca
     2761 agctggaatt tgttagtaag acgatccaga cgcataactc ctcccataac aggtcaaaat
     2821 tgctactgga gattaaatga ggtcatccct caattattca aggtgaatga cctgaattat
     2881 gtgaaaagaa agttacccgt accggatcgt cttgattctt taggttatat cagccaaata
     2941 aaacttgcca tacgacctgt cgtcttgtcg cgacgataag agaagaaagt ctcactttcg
     3001 ctaaaggtgc agcgatcccc gccatagaca tgttcaacgc cagtattcgc cagacgttgg
     3061 cgtgcaagct gataaatatc cgccagaaat ttttccccgt gcggcaaaaa tgcgctatcg
     3121 gcttgcgcat cttttgctaa aaatgcgtca cgcacttccg gccccacttc aaacgcggcc
     3181 gggccaatcg ccggacctaa ccaggcgatg atattttctg gtttgtcagc aaagcaggtg
     3241 acagtttcct ccagtacgcc ttcacataat ccgcgccagc ccgcatgagc cgccgccact
     3301 tctgtcccct cacggttaca gaatagcaca ggcaggcagt ctgccgtcat taccgcgcag
     3361 acggttcctg gcgtattgct gtaagacgca tccgcacgtt tggaggcata aggttctccg
     3421 gtaagcctca atacattttt accgtgaacc tgttcaagcc agacaggttt cgaaggcaga
     3481 ttgcccgccg cgaacagacg cttgcggttc tcttcaacat gctccgggtt atcgccgcaa
     3541 tgcgcgccca gattcagcga gtcgtaaggc gataaactca ccccaccaat acgggtagaa
     3601 ctacaggctg cgacgccttt cggcagcggc cactgcggga caatcagtgc attcataacc
     3661 agtccacatc atctttatga tcttcgaaat cggcgcgcat cgcatcgata aggtccacca
     3721 tatcttgtgg aatcggcgcg tgccactcca tttcgatacc cgatacagga tggtagagac
     3781 gcagcatcgt tgcatgcagc gcctggcggt caaacttacg cagcgtggaa ataaattctt
     3841 ccgatgcgcc tttcggtgga cgtggacgac caccgtagac ctgatcgccc actaacggat
     3901 gcgtaatatg cgccatatgc acgcggatct ggtgcgtacg cccggtctcc agacgcaacc
     3961 taagacgcgt gtgcacacgg aaatgttcca taatgcggta gtgggtcacc gccggtttgc
     4021 ccataggatg caccgacata tgggtacgtt tggtcgggtg acgactgatg ggttcattca
     4081 ccgttcctcc cgccgtcata tgtccgatcg cgaccgcttc atattcgcgg gtgatctcgc
     4141 gcagctgcaa agactccacc aggcgcgttt gcgccggaac ggttttggcc accaccatca
     4201 gccccgtcgt gtccttatcc agacgatgca caatgcccgc gcgcgggaca tccgcaatcg
     4261 gcggataata atgtagcaac gcgttcagta ccgtaccgtc cgggttaccc gcgccaggat
     4321 gtaccaccag atcgcgtggt ttgttgataa ccagaatatc gtcatcttca taaacaatat
     4381 ctaacgggat atcctgcgct tcaaaacgaa tctcttcgtc gatctccgca tcaatagcca
     4441 cccgctcgcc gcctaacact ttttcttttg gcttatcgca aagttgacca ttgaccaaca
     4501 cgcgctgatt caaaatccat tcttttatac gcgaacgtga ataatccggg aacatttcgg
     4561 ccaaagcctg atctaagcgt tgaccgagtt ggttttcgga gaccgttgcg gtgagttgta
     4621 ctcgttgtgc catatacagc ttcttcgttt aacgttgggt tttacggctt tgccgtttaa
     4681 tatagtgtgc tattgtagct ggtcttaacc gggagcagga acagagaatc tcccgtaaaa
     4741 cattttgagg aaagtcaaaa cgtcatgacg cgcatgaaat atctggtggc agcagccacg
     4801 ttgagcctgt ttctggcggg ttgctcgggt tcaaaggaag aggtgcccga taatccgccg
     4861 aatgaaatct acgcgactgc tcagcaaaag ctgcaggacg gtaactggaa acaggcaata
     4921 acgcaattgg aagcgttaga taatcgttat ccattcggac cgtattctca gcaggtgcag
     4981 ttggatctta tctacgccta ttacaaaaac gccgatttgc cgctagcgca ggccgccatc
     5041 gatcgtttta tgcgtcttaa tccaacgcac cctaatattg actatgtcat gtacatgcgc
     5101 ggcctgacga acatggcgct ggatgatagc gtgctgcagg gtttctttgg cgtcgatcgc
     5161 agcgatcgcg atccgcaaca tgcgcgggcg gcgttcaatg acttttcgaa actggtacgc
     5221 agctatccta atagccagta caccaccgac gccactaagc gtctggtatt cctgaaagac
     5281 cgtctggcga aatatgaata ttccgtcgca gagtactata ccgcgcgcgg cgcatgggtt
     5341 gcggtcgtaa accgggtaga aggtatgcta cgcaattatc ctgatacgca ggccacgcgc
     5401 gatgcgttgc cgctgatgga aaacgcctat cgtcagatgc agctgaatgc gcaggctgac
     5461 aaagtcgcga aaattattgc cgctaacagc aaaaacacct gaagcaatac caacaagcaa
     5521 aacggcagcc ttccggctgc cgttttttta ttcgatatct gatgcaacag aaatgatttc
     5581 actgcaacgc atccagtcaa atatggcctg ctttcagcca ttcctcaagt aaaagatcgc
     5641 ttcttcctgc gatgcctcac aaaaagttcg ccttgacaaa aagtgacaaa ataatgtgat
     5701 ttacatcaca cattttgaca ttaagaacgg tatgctggaa tcaccaagac gggaaagaca
     5761 agaggtaaaa tttatgacaa tgaacattac cagtaaacaa atggaaatta ctccggcaat
     5821 ccgccaacat gtcgcagacc gtctcgccaa actggaaaaa tggcaaactc acctgattaa
     5881 tcctcatatc attctgtcta aagagccaca gggctttatt gctgacgcca ccattaatac
     5941 accgaacgga catctggtcg ccagcgcaaa acacgaagat atgtacaccg ctattaatga
     6001 attgatcaac aagctggaac ggcagctcaa taaagtgcag cacaaaggcg aagcccgtcg
     6061 tgccaccgca tcggtgaaag atgccagctt cgtcgaagca gaagaagagt agtcccttac
     6121 attgagtgta tcgccaacgc gccttcgggc gcgttttttg ttgacaggat taaaacagta
     6181 cgggtactgt acttacgtac acaaaggaaa cagttatgaa gctcacccgg tttttcttcg
     6241 cattcttttt tatcttcccc tgaccgggag gcgtttcgtc atgtgataaa gaatgcgaag
     6301 a
//
LOCUS       DAJVKX010000190         6181 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.190, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000190 DAJVKX010000000
VERSION     DAJVKX010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6181
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.190"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            16..426
                     /locus_tag="OPY25_004201"
     CDS             16..426
                     /locus_tag="OPY25_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929660.1"
                     /translation="MLPEHLVSSHFRLSSPPPEATENSKNLSQGKTKLSDYEPDILIC
                     ANATGQHRNVLFEERDRHIKERLYCVAKIETFARLINALQAEGDIDAQTLSKILADKT
                     AMINEKGNAIWLNLITRETNMPLFYSLEDKDERS"
     gene            413..817
                     /locus_tag="OPY25_004202"
     CDS             413..817
                     /locus_tag="OPY25_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCS0929661.1"
                     /translation="MKEVEDNNVYLALDNHKSDEFILKQNLAALIASKNATLEKVTQE
                     VVSIPAALVRLKWQNRREMYALQVKEEIYGATINAIIEQHPELRDKIMSRLESDWQHL
                     LARETATLRLTRKLSDGDYRTRNVTTVARQEK"
     gene            941..1825
                     /locus_tag="OPY25_004203"
     CDS             941..1825
                     /locus_tag="OPY25_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCS0929662.1"
                     /translation="MSHLYDPTTQYYTGEYPKQKQPAPGVQAKMTPVPDCGEKSYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGTDVAINYLPAEEEDAQQVKALIEECGRKA
                     VLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVN
                     VFALFWITQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(1938..2363)
                     /gene="exbD"
                     /locus_tag="OPY25_004204"
     CDS             complement(1938..2363)
                     /gene="exbD"
                     /locus_tag="OPY25_004204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HCS0929663.1"
                     /translation="MAMRLNENLDDNGEMHEINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNTMFIGNDPVTDDTMIAELTALTEGKKDTTI
                     FFRADKTVEYETLMKVMDMLHQAGYLKIGLVGEETAKAK"
     gene            complement(2370..3104)
                     /gene="exbB"
                     /locus_tag="OPY25_004205"
     CDS             complement(2370..3104)
                     /gene="exbB"
                     /locus_tag="OPY25_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HCS0929664.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFTQKRRLKREQLQLADARSLDQASDIAAGFSAKSLSAQLINEAQNELELSQGSE
                     DNEGIKERTGFRLERRVAAVGRYMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNIFARQIGSYKATLGDVAAQVLL
                     LQSRDLDLNASASAQPVRAAQKLRVG"
     gene            3356..4543
                     /gene="metC"
                     /locus_tag="OPY25_004206"
     CDS             3356..4543
                     /gene="metC"
                     /locus_tag="OPY25_004206"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HCS0929665.1"
                     /translation="MTDKQLDTKLVNAGRSKKYTLGSVNSVIQRASSLVFDTVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQEAMCELEGGAGCALFPCGAAAVANTILAFVEQGD
                     HILMTNTAYEPSQDFCSKILGKLGVTTSWFDPLIGADITQHIQPNTKVVFLESPGSIT
                     MEVHDIPTIVSAVRRVAPDAVIMIDNTWAAGVLFKALEFDIDISIQAGTKYLIGHSDA
                     MVGTAVANARCWEQLRENAYLMGQMLDADTAYMTSRGLRTLGVRLRQHQESSLKIAAW
                     LANHSQVARVNHPALPGSKGHAFWKRDFTGSSGLFSFVLNKKLTEAELSAYLDNFSLF
                     SMAYSWGGYESLIIANQPEQIAAIRPAGGVDFTGTLVRVHIGLESVDDLIADLAAGFA
                     RIV"
     gene            4683..5342
                     /locus_tag="OPY25_004207"
     CDS             4683..5342
                     /locus_tag="OPY25_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCS0929666.1"
                     /translation="MAVIQDIIAALWQHDFAALANPHVVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLLLAGALIAQDVMHFLPTIGILTAAASLGCWLSYIQGRWLGNTRTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLSNRRFQFFNWLS
                     GLLWVTVVTSFGYALSMIPFVKRHEDQVMTFLMILPVALLVAGLLGTLVVVIKKKYCN
                     A"
     gene            complement(5406..>6181)
                     /locus_tag="OPY25_004208"
     CDS             complement(5406..>6181)
                     /locus_tag="OPY25_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCS0929667.1"
                     /translation="TPVMYQPGIIFLFSGHKIGYINKRKFRYDANEYLLLTVPLPFEC
                     ETWATPEVPLAGIRLDIDVLQLQELLMDIGEDERFQLPMAASGINSATLSDEILCAVE
                     RLLDVMERPLDARILGKQIIREILYHVLMGPRGGALLALVSRQTHFSLISRVLKQIEM
                     KYTENLNVEQLAAEANMSVSAFHHNFKAVTSTSPLQYLKSYRLHKARMMMIHDGMKAS
                     AAAMRVGYESASQFSREFKRYFGVTPGEDAARMRTMQGS"
BASE COUNT         1515 a         1647 c         1560 g         1459 t
ORIGIN      
        1 aaaggatatt tagtcatgct tcctgagcat ctggtttcct ctcattttcg cctgtcatcg
       61 ccgccccctg aagccacaga aaacagtaaa aatttgtctc agggaaagac aaaactcagc
      121 gattacgagc ccgatatttt aatttgcgct aacgcaaccg ggcaacacag aaacgtatta
      181 tttgaagaac gcgaccgtca tattaaagaa cgtctgtatt gtgtggctaa aattgaaacg
      241 tttgcccgcc tgataaacgc actacaggca gaaggcgata ttgatgccca aacgctaagt
      301 aaaatactgg cggataaaac cgcaatgata aatgaaaaag gtaatgccat ttggcttaat
      361 ttaatcactc gcgaaaccaa tatgccgcta ttttattcac tggaagataa agatgaaaga
      421 agttgaagac aataacgttt atttggcttt agacaaccat aaaagtgatg aatttatctt
      481 aaagcaaaat cttgcagcgc taatcgccag taaaaatgcc actctggaaa aggtaacgca
      541 ggaagtggta tccataccgg cggcgttagt gcgcctgaag tggcaaaacc gacgagagat
      601 gtatgcgtta caggtcaaag aggagattta tggcgcgacc atcaatgcta ttatcgagca
      661 gcatcctgaa ttacgagaca aaattatgtc tcgtcttgaa agtgactggc agcatctgct
      721 ggctcgcgag acggcaacct tacgtctgac gcgtaagctt tccgatggcg actaccggac
      781 gcgcaacgtc accacagtcg cacggcaaga aaaataacct tcatagctag ttaactctgt
      841 tgtgaatacg ggcgaagcat aaggatcgtt ctgattctcc ctcttacggt agtaaaagtg
      901 tctacgctta aagggtgttc aacctgaagg gagaagctca atgtctcatc tatacgaccc
      961 taccacgcag tattacaccg gcgagtatcc taagcaaaaa cagccggcgc ccggcgtcca
     1021 ggcgaaaatg acgcctgttc ctgactgtgg tgaaaaaagt tatgtcggca gtggtcgcct
     1081 taaagatcgt aaggcgctgg tgacaggggg cgactccggg attgggcgcg ctgccgctat
     1141 cgcttacgcg cgtgaaggca cagatgtcgc gatcaactat ctgccagcgg aagaagagga
     1201 cgcccagcag gttaaagcgc tgattgagga gtgcggccgt aaagcggtgt tattgccggg
     1261 cgatcttagc gacgaatctt tcgcccgttc gctggtccat aaggcgcgcg aagcgctggg
     1321 cgggctggac attctggcgc tggtagccgg taaacagacg gcaatcccgg agataaaaga
     1381 tctaaccagc gagcaatttc agcaaacctt cgccgttaac gtttttgccc tgttctggat
     1441 aacccaggaa gcgattccgc tgctgccaaa aggcgccagt attatcacaa cgtcgtctat
     1501 ccaggcctat cagcccagtc cgcacctgct ggattatgcg gcaaccaagg cggcaatcct
     1561 taattacagc cgcggcctgg cgaaacaggt ggcggaaaaa ggaattcgcg tgaatattgt
     1621 cgcgcctggc cctatctgga cagcgctgca aatttccggc ggccaaacac aggataaaat
     1681 tccgcagttt ggccagcaga cgccaatgaa gcgggccggt caaccggcag agctggcgcc
     1741 ggtgtatgtc tatctggcaa gccaggaatc aagttacgtt accgcagaag tgcacggcgt
     1801 gtgcggcggg gaacatttag gctaacgcat gaagtcgatt aaggtggcgc aattctgtta
     1861 agcaaggcgc catcttaggc aataaaaaag ccgggtggcg acttcgcctt acccggccta
     1921 cagcatcagc agaatactta tttcgctttc gcggtctctt cgccgaccaa accaatcttg
     1981 agatagcccg cctgatgcag catatccatc actttcatca gggtttcata ctctacggtt
     2041 ttatccgcac ggaagaaaat cgtagtatcc tttttccctt ccgtcagggc cgttagctcg
     2101 gcaatcatcg tatcatccgt caccggatcg ttaccgataa acatggtgtt atccgctttc
     2161 accgacagat aaaccggttt ttccggacgc ggctgtggcg tactggtaga agcgggcaga
     2221 ttcaccttga cgtccaccgt cgccagcggc gcagccacca taaagataat cagcagaacc
     2281 aacatgacat cgataaacgg cgtcacgttg atttcatgca tttcgccgtt gtcatccagg
     2341 ttctcgttaa gacgcattgc catgacgcat taccctaccc gtaatttctg cgcggcgcgt
     2401 accggctgcg cactggcgct cgcattcaga tcaagatcgc ggctttgcag cagcaatacc
     2461 tgcgccgcca cgtcgcccag cgtcgctttg taactgccta tctgacgtgc gaagatgttg
     2521 taaatgacga ccgccgggat cgcggctacc agcccaatcg ccgtcgccag cagcgcttcc
     2581 gcaataccag gagcgaccac cgccaggttg gtggtctgcg tttgcgcaat accgatgaag
     2641 ctattcataa tgccccatac ggtgccaaac aacccgacga agggggaaat ggcgccgatc
     2701 gtcgccagat aaccgttgcc tcgtcccatg tagcggccaa ccgctgcgac gcgacgttcc
     2761 agacggaagc cggtacgttc tttaatccct tcgttatctt cgctgccctg agagagttcc
     2821 agttcattct gcgcttcatt gatgagctgt gcgctgaggc tttttgcgct gaaacctgcc
     2881 gcaatgtcgg aagcctgatc taaagagcgc gcatcggcta attgcagttg ttcgcgcttt
     2941 aagcggcgct tttgcgtgaa aaattcaacg cttttactga agaagatagc ccaggtgacg
     3001 actgacgcca gaatcaaacc aatcatcacg cacttcacga caatatcggc gtgctgatac
     3061 atgccccaga cggaaagatc cgtctgcatc aaattattac ccactctgta tctccaggac
     3121 gcaaatcaca aaatctgagc ataataatat caaaacaacg tcgaattgat agtcgttctc
     3181 attactattt acatactgcc gcacctttac tgctttttct ttgcgcttac gcattaaaaa
     3241 agccacctgt ttttattttg gcaaaatttt catctgtatc acacatcgcc agggtgcaga
     3301 tggttatatt catgctagtt tagacatcca gacggttaaa atcaggaaac gcaacatgac
     3361 ggataaacag ttggatacca aactggtaaa cgcaggacgc agcaaaaaat acacgcttgg
     3421 ctcagtgaat agtgtgattc aacgcgcttc ttcactggtg tttgacaccg tcgaggccaa
     3481 aaaacacgct acccgcaatc gcgccaacgg cgaattattt tacggacgcc ggggaacgct
     3541 gactcacttt tcgctccagg aagccatgtg tgaactggaa ggcggcgccg gatgcgcgct
     3601 cttcccgtgc ggtgcggcgg cggtcgccaa caccattctg gcattcgttg aacagggcga
     3661 ccacatcctg atgaccaaca cagcctatga acccagccag gatttctgca gcaaaattct
     3721 cggcaaactg ggcgtgacga caagctggtt cgacccgctc atcggcgctg atatcacgca
     3781 acatattcag ccgaacacga aagtcgtatt tctggaatcc cccggttcta ttaccatgga
     3841 agtacatgat attccgacca ttgttagtgc ggtcagacgc gtcgcgccag acgccgtcat
     3901 catgattgat aatacctggg cggctggcgt tctgttcaaa gctctggaat tcgatattga
     3961 tatctctatc caggcgggca ctaagtatct aattggtcat tctgatgcga tggtcggtac
     4021 tgccgttgca aatgcgcgct gctgggaaca attgcgggaa aacgcctatc tgatggggca
     4081 aatgctcgac gccgacacgg cttatatgac cagccgcggt ctgcgcacgc tcggcgtccg
     4141 actgcgccag catcaagaaa gcagcctcaa aatcgccgcg tggctggcga accattctca
     4201 ggtcgcgcgc gttaatcatc cggccctgcc gggtagcaaa ggtcatgcgt tctggaaacg
     4261 agactttaca ggcagcagcg gcctgttctc ctttgtgctc aataaaaagc tgaccgaggc
     4321 agaattatca gcctatctgg ataacttttc gctgttcagt atggcctact cctggggagg
     4381 ctacgaatcg ctgattattg ctaatcagcc ggaacagatc gccgcgattc gtcccgcagg
     4441 cggcgtagat tttaccggta cgctggttcg agtgcatatt ggtttagaga gtgttgatga
     4501 tttgatcgct gatttagccg ccggcttcgc cagaattgtg taaagttgcc gtggatggac
     4561 atatatgcag acaatttccg tggaaaagtc tgcgtttgtt gcgtccggga tcaaggcatc
     4621 ccggacgatt caggagtaca ataggcagat aaaagcgtaa atgctgttcc acaggaaagt
     4681 tcatggctgt cattcaagat attatcgctg cgctctggca acatgatttt gccgcgctgg
     4741 cgaatccaca cgttgttagc gtcgtctact ttgtcatgtt cgccacgcta tttttagaaa
     4801 acggtctgct gccagcgtca ttcttacccg gcgatagtct gctgctactg gcaggcgcgt
     4861 tgatcgccca ggatgtgatg cattttttgc cgacgattgg cattctcacc gccgcggcca
     4921 gtctcggctg ctggctaagt tatatccagg gacgctggct cggtaatacg cgtaccgtca
     4981 aaggctggct agcgcagctt ccggcaaaat atcatcagcg cgccacctgc atgtttgacc
     5041 gtcacggttt gttagcgttg cttgccgggc gctttctggc gtttgtccgc acgctgctgc
     5101 caacaatggc gggcatttcc ggcctgtcca accgccggtt tcagtttttt aactggttaa
     5161 gcggcctgct gtgggtgact gtcgtgacca gcttcggcta cgcgctcagt atgatcccgt
     5221 ttgttaagcg ccatgaagac caggtaatga catttttaat gatccttccc gtcgcgctac
     5281 tggtcgccgg gctgttaggt acgctggtcg tggtgattaa aaagaaatac tgtaacgcct
     5341 gacgtatcca taatcggcca ggatggcccg gttacgcttc gttgccccgt ggcgggatgc
     5401 cccacttagc tcccttgcat tgtccgcatt cttgccgcat cttcgcccgg cgtaacgcca
     5461 aaataacgtt taaactcccg gctaaactgc gatgcgctct catagccgac ccgcatcgcc
     5521 gcggcgctgg ccttcatacc gtcgtgaatc atcatcatcc gcgctttatg cagtcggtag
     5581 ctttttaaat actgcaacgg cgaggtgctg gtgaccgcct taaaattatg gtgaaacgcc
     5641 gacacgctca tgttcgcttc tgccgccagt tgctcaacat tcaggttctc ggtgtatttc
     5701 atttcgatct gtttaagtac gcgactgatc aggctaaagt gcgtctggcg actaaccagc
     5761 gcaagcagcg ccccgccgcg cggccccatc agcacatgat aaagaatttc gcgaataatc
     5821 tgttttccca gaatccgcgc atccagcggg cgctccatca catccaacaa tctttccacc
     5881 gcgcataaaa tctcgtccga cagcgtggcg gagttaatcc cgctggccgc catcggcaac
     5941 tggaaacgct catcttcgcc aatgtccatg agcaactctt gcagttgcag cacatcaatg
     6001 tcgagccgaa taccggccag cggtacctcc ggcgtcgccc aggtctcgca ttcaaaaggg
     6061 agcggcacgg tcagtaagag atattcatta gcgtcataac gaaacttgcg cttgttaata
     6121 tagccaattt tatggccgga aaagagaaat atgatgccag gctgatacat gaccggcgtg
     6181 c
//
LOCUS       DAJVKX010000191         6174 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.191, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000191 DAJVKX010000000
VERSION     DAJVKX010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.191"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            133..477
                     /locus_tag="OPY25_004209"
     CDS             133..477
                     /locus_tag="OPY25_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929668.1"
                     /translation="MSYKYVGKHGCDVALRMGYKEYPDENAYGDAYYIKDGLKWIFNI
                     TGLKKRLGVYSDDDLRKQNYDVDTYYRVENQQEESADDEMQSLYHNLAVEEGEPVYLE
                     GGMYLYPDGSIR"
     gene            complement(795..889)
                     /locus_tag="OPY25_004210"
     tRNA            complement(795..889)
                     /locus_tag="OPY25_004210"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(853..855),aa:Sec,seq:tca)
     gene            1177..2559
                     /locus_tag="OPY25_004211"
     CDS             1177..2559
                     /locus_tag="OPY25_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HCS0929669.1"
                     /translation="MKSEILSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLLARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSLNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVKLIGGENKALGFQGGIAALSVVAFLMLAFCFFTTKERVEAPATHTSMR
                     EDLRDIWHNDQWRIVGLLTILNILAVCVRGGAMMYYVTWILGKPGVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVSVFWWTNALLAVISVAMFFVPMHATIAMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLALGGALIGWMLAGGGYDA
                     AAKTQNSATISIIIALFTIVPAICYLLSAAIAKRYYTLKSPFLKTILEQLAQGAHRNE
                     QEFTHKELQN"
     gene            2571..4889
                     /gene="yicI"
                     /locus_tag="OPY25_004212"
     CDS             2571..4889
                     /gene="yicI"
                     /locus_tag="OPY25_004212"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HCS0929670.1"
                     /translation="MKISDGNWLIQPGLNLIHPVQVFDVEQHGNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGVIGVRMEHFQGALDNGPHYPLNVLQDINVEMQNNAEFAE
                     LKSGSLSVRVTKGELWSLDFLRNGVRITGSQLKNNGYVQDTNSGRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQSYKNIPFYITNRGYGVLVNHPQCVSF
                     EIGSEKVSKVQFSVESEYLEYFVIDGPTPKDVLNRYTQFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNRFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPVTFPDPKGMIHR
                     LKAKGLKVCVWINPYIGQKSPVFQELKEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     QACEWYADKLKGLVEMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKETVGVEEAVLFARSASVGAQQFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTEQK
                     CRMMPYLYREAARANEAGTPMMRAMMLEFPDDPACDYLDRQYMLGDAVMVAPVFSEAG
                     DVEFYLPEGRWTHLWRNDEVQGSRWHKQQHDFLSLPVYVRDNTLLALGNNSQKPDYAW
                     HEGTAFQLFHLDDGCEAVCEVPATDGSTIFTLQAKRTGNTITVSGEGEARNWTLCLRN
                     ITQISGTKCGSYAGSELGVVVTPQGNEVVITL"
     gene            complement(4992..>6174)
                     /locus_tag="OPY25_004213"
     CDS             complement(4992..>6174)
                     /locus_tag="OPY25_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HCS0929671.1"
                     /translation="DVPATNVLIEGSIDHDQMMLNTVGADMARGALTGVARRNADGSW
                     VVENLRLNDIRLQSDKSLSEFFAPLTTVPSLQIGRLEVTDSSLQGPDWAVTDLDLSLR
                     NLTLRKEDWQSQEGKLSMNASEFIYGSLHLLDPILNAEFSPQGVALRQFTTRWEGGMV
                     RTSGAWLRESKALILDDTAIAGLEYTLPENWKQLWMKPLPDWLNSLTLKKFSASRNLV
                     IDIDPTFPWQITALDGYGANLELVQHHQWGVWSGNATLNAAAATFNRVDVRRPSLSLT
                     ANASTVNISDLSAFTEKGILEATASVSQQPQRQTQISLNGRGVPMDVLQQWGWPALPI
                     AGDGNIQFTASGNIQADAPLKPTVNGQLHAVNAQKQQIMQTMQAGVVSGGEVTSTEPA
                     L"
BASE COUNT         1391 a         1594 c         1701 g         1488 t
ORIGIN      
        1 gatacggact taggggataa tataacgtgt actttagttt aaattctatc cttcatgtgg
       61 cataggttat caggataggt tttcgttatg aattttatct gggatattga agcaacatat
      121 tgtggggggg atatgagtta taaatatgtt ggtaagcatg gctgtgatgt tgcattgcgg
      181 atgggctata aagaataccc cgatgaaaat gcttatggtg atgcctatta tattaaagat
      241 gggttaaaat ggatatttaa tataacaggc ttaaaaaaac ggcttggcgt atacagcgac
      301 gacgatctcc gtaaacagaa ctatgatgta gatacctatt atcgggttga aaaccaacag
      361 gaagaaagtg cagatgatga aatgcaatcg ctatatcata atttagcggt agaagaagga
      421 gaacccgtgt atctggaggg aggcatgtat ctttatccgg atggctctat acgttgatct
      481 cataattttg gtctggtaag cgttatctct tttgagaaag gatgagtctg taagtatgac
      541 ccacaagctc gtttggtgat tagttaagtc ccgcccgcgt tagtcctggc gtacttttat
      601 cccttctttg cggacgatat cccacaataa atggacgttc ggttttagca atcggtaaat
      661 ggtgattaat aaaataatat tccactttct ctctccacct ttcctttcgt attatatgca
      721 agaactagtc ttaataataa gcaaatactt tgtcccgaaa tagaggacga atggtgggca
      781 tgagagaagg attttggcgg aagatcacag gagtcgaacc tgcccgggac cgctggcggc
      841 cccaactgga tttgaagtcc agccgcctca ccggagacga cgatcttccg cgcctcgatt
      901 gctacatgga ggcgcgcgca ttatagctac ttcctggcgt ttccacatcc cctcccgtgc
      961 ttttttaact tccctttcct tctgccatga tcggtttcat ataaaccccc ataaaatcca
     1021 ttagttacat ttcatcacac tttttggcgc taccctgatc acagaaaaca agaatcgtaa
     1081 tttgataacc aaataacgga atattcacgc tcgcagggaa ggtttacaaa aactgtaacc
     1141 ggtatcagtg agcgttgtga gcgttaagga tgcgtaatga aaagtgaaat tctctccgtt
     1201 aaggagaaga ttggctatgg tatgggcgat gccgccagcc acatcatctt tgataacgtc
     1261 atgttatata tgatgttctt ctataccgat attttcggca ttcccgctgg ttttgtcggc
     1321 accatgtttt tactggcgcg tgcgcttgat gccatctccg acccttgcat gggcctgttg
     1381 gccgaccgta cccgctctcg ctggggcaaa ttccgaccct gggtgctgtt tggcgcgttg
     1441 ccgtttggta tcgtttgtgt gctggcttat agcacgccgg atctcagtct gaacggcaaa
     1501 atgatttatg ccgccatcac ctacacgttg ctcacccttc tgtatactgt ggtcaacatc
     1561 ccttactgcg cgttgggtgg tgtaataacc aatgacccaa cgcagcgtat ctccctgcaa
     1621 tcctggcgct ttgtgctggc aacggcgggc ggaatgctct ctaccgtact gatgatgcct
     1681 ctggtgaaac tgattggcgg cgagaataag gcgctgggct tccagggggg gatcgcggcg
     1741 ctctcggtgg tggcgttcct gatgctggcg ttctgctttt ttaccaccaa agagcgcgtt
     1801 gaagcgcctg ccacccatac ctccatgcgt gaagacctgc gtgatatctg gcacaacgac
     1861 cagtggcgca tagtcggcct gctcaccatc ctgaatattc tggcggtatg cgtgcgcggc
     1921 ggggcgatga tgtattacgt cacctggata ttgggcaaac cgggcgtgtt tgtcgccttc
     1981 ctcaccacct attgcgtcgg caacctgatt ggctcggcgc tggcaaaacc gttgaccgac
     2041 tggaaatgca aagtgagcgt tttctggtgg accaacgcct tactcgcagt aatcagcgtg
     2101 gcgatgttct tcgtaccgat gcacgccacg atcgctatgt tcgtctttat cttcgtgatt
     2161 ggcgtattgc accagttagt cacgcctatc cagtgggtga tgatgtctga caccgtcgac
     2221 tacggcgaat ggtgtaacgg caaacgcctg acggggatca gttttgccgg cacgttgttc
     2281 gtgctgaaac tgggtcttgc cctcggcggg gcgctgattg gctggatgct ggcaggcggc
     2341 ggttacgacg cggcggcgaa aacgcaaaac agcgccacga tcagcatcat catcgctctg
     2401 ttcactatcg tcccggccat ctgttatctg ctgagcgccg cgatcgctaa acgctactac
     2461 accctgaaaa gcccgttcct gaaaaccatt ctggaacaac tggcgcaggg cgcacaccgc
     2521 aacgaacaag aatttaccca taaagaattg caaaactaaa ggaacagact atgaaaatta
     2581 gcgacggaaa ctggctgatc cagcctggcc ttaatttgat tcacccggtt caggtgttcg
     2641 acgttgaaca gcacgggaat gagatggtgg tctatgccgc gccgcgcgat gtccgcgaac
     2701 gaacctggca actggatacc ccgttgttta ccctgcgctt tttctcgcca caggaaggag
     2761 tgataggtgt acggatggaa cacttccagg gcgctttgga taacggccca cattatccgc
     2821 tcaatgtctt gcaagatatc aacgtggaga tgcagaacaa cgccgaattt gccgaactca
     2881 agagcggcag cctgagcgtg cgtgtcacca aaggcgagct ctggtcactg gattttctgc
     2941 gcaacggtgt acgtatcacc ggtagccagt tgaagaataa cggctatgtg caggatacca
     3001 acagcgggcg caactacatg ttcgagcgtc tggatctcgg cgtgggcgaa accgtctacg
     3061 ggctgggcga gcgctttacc gcgctggtgc gtaacggtca gacggtggag acctggaacc
     3121 gtgacggcgg caccagcacc gagcaatcgt acaagaatat cccgttctat atcaccaacc
     3181 gtggctacgg tgtgctggtg aatcatccgc agtgcgtgtc gtttgaaatt ggctccgaga
     3241 aagtctccaa agtccagttc agcgtcgaga gcgagtatct ggaatacttc gtcatcgacg
     3301 gcccgactcc gaaagacgtg ctgaaccgct atacccaatt tacgggtcgt ccggcgctgc
     3361 cgcccgcctg gtcgtttggc ctgtggctga ccacctcatt taccaccaac tacgacgaag
     3421 cgaccgttaa ccgctttatc gacggtatgg ccgagcgcaa tctgccgctg catgtcttcc
     3481 acttcgactg tttctggatg aaggccttcc agtggtgcga ttttgaatgg gacccggtga
     3541 ctttccccga tccgaaaggg atgattcacc gcctgaaagc gaaagggctg aaagtctgcg
     3601 tgtggattaa cccctacatc ggccagaaat ccccggtttt ccaggagctg aaagagaaag
     3661 ggtatttact taaacgcccg gacggctcct tgtggcagtg ggataaatgg cagccgggac
     3721 tggcgattta cgacttcacc aacccgcaag cctgcgaatg gtatgccgac aagctgaagg
     3781 gcctggtgga gatgggagtg gactgcttca aaactgactt cggcgaacgc attccaacgg
     3841 atgtgcagtg gtttgatggt tcagatccac agaaaatgca caaccattat gcctacatct
     3901 acaacgaact ggtgtggaac gtgctgaaag agaccgtggg cgttgaagag gcggtgttgt
     3961 tcgcccgttc cgcctcggtg ggcgcgcaac agttcccggt gcactggggc ggcgactgct
     4021 acgccaatta cgaatcgatg gcggaaagcc tgcgcggcgg gctgtccatc ggcctgtcag
     4081 ggtttggctt ctggagccat gatattggcg gattcgagaa taccgcgccg gcgcatgtct
     4141 acaagcgttg gtgcgcattc ggcttgctct ccagccacag ccgcctgcac ggtagcaaat
     4201 cctaccgggt tccgtgggcc tatgacgacg agtcctgtga cgtggtgcgc ttcttcaccg
     4261 aacagaagtg ccggatgatg ccgtatctgt atcgggaagc ggcgcgcgcc aacgaagccg
     4321 gtacgccaat gatgcgggcg atgatgctgg agtttccgga cgatccggcg tgtgattatc
     4381 ttgatcgcca gtacatgctg ggagatgcgg tcatggtagc gccggtattt agtgaagcgg
     4441 gcgacgtgga gttctacctg ccagaaggcc gctggacgca cttgtggcgc aacgatgaag
     4501 tgcagggcag ccgctggcat aaacagcagc atgacttcct gagcctgcca gtgtacgtgc
     4561 gtgacaatac actactggcg ctgggcaaca atagccagaa gcccgattac gcctggcatg
     4621 agggtacggc cttccagtta ttccatctgg atgacggttg cgaagcggtc tgcgaagtcc
     4681 ctgctacgga tggttcgaca atctttacgc tgcaggcgaa acgcacaggc aataccatta
     4741 cggtgagcgg cgaaggcgag gcgcgcaact ggacgctgtg tctgcgtaat attacgcaga
     4801 ttagcggtac caaatgcggc tcatatgcgg gaagtgaact gggcgtagtg gtcaccccgc
     4861 agggaaatga agtggtgatt acgctttaaa tctgaatcgc cggatggcgc cgtgagctgc
     4921 gcttatccgg cctacaaatg agcaagaacc gtaagcccgg taagcgccag cgccaccggg
     4981 caagccctca attacagcgc tggctccgtt gacgtaactt ccccgccgga caccacaccc
     5041 gcttgcatcg tttgcattat ctgctgcttt tgtgcgttga ccgcgtgtaa ttgcccgttt
     5101 accgtcggtt tcaacggcgc atcggcctga atattgccgc tggccgtgaa ctgaatattg
     5161 ccatcgccag caatcggtaa tgccggccag ccccactgtt gtagcacatc cattggtacg
     5221 ccgcgtccgt tcaggctgat ttgcgtctga cgctgcggct gttgtgatac gctggcagtg
     5281 gcttccagta tccctttttc agtaaacgcg ctcagatcac tgatgttgac cgtgctggca
     5341 ttcgccgtca acgacagcga cgggcggcgc acgtccacac ggttaaaggt tgccgctgcg
     5401 gcgttgaggg tcgcattgcc gctccagacg ccccattgat gatgttgtac cagctccagg
     5461 tttgcgccgt agccgtccag agcggtgatt tgccacggga aggtcgggtc gatatcgatc
     5521 accagattgc ggctggcgct gaattttttc agcgtcaggc tgttcagcca gtcgggcaac
     5581 ggcttcatcc ataactgctt ccagttttcc ggcagcgtat actccagccc ggcgatagcg
     5641 gtatcgtcca gaatcagcgc tttgctctcg cgtaaccagg cgccggaggt tctgaccata
     5701 ccgccttccc agcgggtggt gaactggcgt agcgcaacgc cctgtggtga aaattcggcg
     5761 ttcaggattg gatcgagcaa gtgcagcgag ccgtaaataa actcgctggc attcatcgat
     5821 aatttacctt cctgactttg ccagtcttct ttgcgcagag tcagattgcg caaactcagg
     5881 tcaagatcgg tgactgccca gtctggtcct tgcaggctgg agtccgtcac ttcaagacga
     5941 ccaatctgca aagatggaac cgtagtaagc ggcgcgaaaa actcgctcag ggatttatcg
     6001 ctttgtaacc ggatatcatt cagccgcaga ttttcaacga cccaactacc atcagcgtta
     6061 cgccgggcga cgccggttaa cgctccgcgc gccatatcgg cgccgacggt gtttaacatc
     6121 atctgatcat ggtcaatact gccttcaata agcacattcg tggcgggaac gtcg
//
LOCUS       DAJVKX010000192         6170 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.192, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000192 DAJVKX010000000
VERSION     DAJVKX010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6170
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.192"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(96..551)
                     /locus_tag="OPY25_004214"
     CDS             complement(96..551)
                     /locus_tag="OPY25_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0929672.1"
                     /translation="MRKKTLDAAEADAAQRLRDIWNEKKVSLRLTQEKAADALGFSTQ
                     ATVSQYLNGSIPLNTDATLKFSALLGVKPEDIRPDLAELMNYVRKSGAHVQDYSAAGW
                     RLLKPEDAELIALYERLPHSEKERHLSELKEKVSEFDRLFEELLATRKQ"
     gene            660..893
                     /locus_tag="OPY25_004215"
     CDS             660..893
                     /locus_tag="OPY25_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929673.1"
                     /translation="MDLKTYLKTSGVRQQDFAQVVGETQGYVSRVASGKCLLGAATAL
                     KWAAATGYQVTPHDLLPNIYRKPTDGLPEQNAA"
     gene            958..1404
                     /locus_tag="OPY25_004216"
     CDS             958..1404
                     /locus_tag="OPY25_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929674.1"
                     /translation="MENLDELKREIFNWAAERGQEHVAIEITRMWFRMGGNTNCVKLH
                     PMEDSKGNADWRAINNNRQQIFRWLRGETKAARIKTKALAMAMEAALPAERYAQLGMT
                     TQQLICIAIRDFAAAIIALLLDARDRPQRIAQALQAIQETQRLTSV"
     gene            1427..1651
                     /locus_tag="OPY25_004217"
     CDS             1427..1651
                     /locus_tag="OPY25_004217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929675.1"
                     /translation="MQTSTDRITWRNGWRLNGEPSCAHDVRGIFEERLSAKKWEIYEK
                     RKAEMIETCVFLTPKDYEIACRELAELLGI"
     gene            1654..2637
                     /locus_tag="OPY25_004218"
     CDS             1654..2637
                     /locus_tag="OPY25_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0929676.1"
                     /translation="MSMTLMARAMAIKTGNPIRKLVLIKLADNANDNGECWPSYQHIA
                     DHCECSRSAVRTHIDALIGMGVLTKENRMGINNGKGNTSNVYYLNLDTPVPPKSTAPV
                     PSKITGMPLENTPPMPCGGTRTSHSFEPVNEPNDPPNPQKGEGDELILADAKKALEFY
                     NEQTGTRCRDVKPFIPMLTPTQTREAYTLAELQLVIRWVLATWRRRGSGLPKPSNICR
                     VNRFDGYLADAEAWATTEADVDPDAVMNGYNEIFADTLPAAELDADRRRMIIRLAAHM
                     KNKTTGAFLGYFEKFRADAPDFYFGSNGGWRASFDYLMKPETLRNTREGSL"
     gene            2634..4022
                     /locus_tag="OPY25_004219"
     CDS             2634..4022
                     /locus_tag="OPY25_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCS0929677.1"
                     /translation="MTPQELEACVLAGLLNGGATPDAFDVIASTPEESFSIGFYRRAF
                     SEIKKQALTNGMIDMLFISEALGGSSLADLSEISRIPATIPNLKGYAGKMVKAWRSRA
                     LAKLLQDGADGIRNAANQEQRDQVVEKAVAQLLDMTAESGDVQPVHINELLPAYMDTV
                     QKRMEGDESTRNLLTGIADLDNATGGINQTDLVVVAGRPGMGKTEFALTVVEGVTAKG
                     GGALIFSMEMAAAQIVERSLAGAGNLSVSRLRNPQDMYDEDWARLTAAIGELTDRDIW
                     IVDATDLTVEQIRAIAETHKRRHPHLAMIMVDYLGLIKKPKAERNDLAVAHISRNLKT
                     MAMRLHTPTFALSQLSRAVDARPAAQRRPVMSDLRDSGSIEQDADSILFLYRDEVYNP
                     ESPAAGVAEVILGKCRFAAAGTVVYQEFKNGHFLPIDQHIGKEKTRIQLEAAKPRKPH
                     RKYAEKYNTDAF"
     gene            4061..4741
                     /locus_tag="OPY25_004220"
     CDS             4061..4741
                     /locus_tag="OPY25_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929678.1"
                     /translation="MTDLIYPKVATADDACDWTNVIIWRMNAGARARSRSVYVPCPRP
                     VPVPGLTARTAPKTKKSKPVETNPRCFSKTHTGTVIYSGGEKTVKLRETATVWTSGSK
                     ENYDKKTGYRVGIKSRCRLLLDSIKPIANPTESPLPQKSSELPAEYLVAIMKGKTLSY
                     QGIMSAIKKYYPDIKISLEQLQKRVFALCMSNFVGIERHDDMPVTHFTLKSVDPRFYV
                     HSEKNMRA"
     gene            complement(5040..5570)
                     /locus_tag="OPY25_004221"
     CDS             complement(5040..5570)
                     /locus_tag="OPY25_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012773203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RloB domain-containing protein"
                     /protein_id="HCS0929679.1"
                     /translation="MAKKKVVRRTINKTLLLVGEGYAEKAFLSHLKSLFSNGKFKVTV
                     ITAGGKGPEHIITHAISCKNCDGYDFVIVLLDTDLCWPKTYKERAISAGINLVGSQPC
                     LEGLLLDVIGKPKENTNSGCKKRLHPLLSGPCTERDSYAELFNIDILEKTTNKQIQFI
                     IEALKGKEHRSVITHP"
     gene            complement(5590..>6170)
                     /locus_tag="OPY25_004222"
     CDS             complement(5590..>6170)
                     /locus_tag="OPY25_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012773202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCS0929680.1"
                     /translation="GKVLDATECYEEDPEIFEKAKKYLTRMDFGLKDIKIKKEEIIDK
                     KTGETETRVLPYGIHIHDGQEFEVPFIMESTGTQACYYFIYKLISALHYGGVAVIDEL
                     DSDLHPYMIRELLDMFANDGINKQSSQLIFSCHTAEILKSLKKHNVYLVEKSNSISEA
                     WRLDDIQGLRSQDNLYAKYITGALGGVPNINI"
BASE COUNT         1727 a         1413 c         1425 g         1605 t
ORIGIN      
        1 gattaaaata atcgtaatgc gaataaaatt tgtatgttat tgataaaaaa gaataaaaaa
       61 aatcccggcg atgcgggatt atttgggagg ggaatttact gttttcttgt ggctagaagt
      121 tcttcaaaaa ggcggtcaaa ctcgctaact ttttctttta attcagatag atgcctttct
      181 ttttcactgt gaggaagtct ttcataaagt gctatcaact cggcgtcctc tggtttcagg
      241 agtcgccagc cagcagctga ataatcttga acgtgggctc ctgatttccg gacataattc
      301 attaattcgg caaggtcagg tctaatgtct tcaggtttta caccgagaag agctgaaaat
      361 tttaatgtcg catctgtgtt taacggaata cttccattca aatactgact gactgtagcc
      421 tgggtactaa agccgagagc atccgccgcc ttttcctgag taagacgtaa agatactttt
      481 ttctcgttcc atatgtcacg cagcctttgg gctgcatcag cttcagctgc atcaagcgtt
      541 ttctttctca tggcacccat attattcgta aaattaattt cctcccaatc gtgtaactat
      601 tgacatgtgt gtattcgcaa tactaatatt catgtgtcac atacatttat ggaggacaaa
      661 tggatctcaa aacctatcta aagacctctg gcgttcgcca gcaggatttc gctcaagtgg
      721 tcggtgagac gcagggctat gtcagtcgtg ttgcatctgg aaaatgcctt cttggtgctg
      781 caactgcatt gaaatgggcc gcagcaactg gctaccaagt tacaccgcat gatctactcc
      841 ccaatattta tcgaaaacca actgacgggc tgccggaaca gaatgcagct taacaaaggg
      901 cgtatttgaa atctgattac gcttaatcag gttttcagcg acaggagacg cgaagaagtg
      961 gaaaacctcg acgaattgaa aagagaaatc ttcaactggg ctgctgagcg tgggcaggag
     1021 catgttgcta ttgagatcac tcgcatgtgg tttcgaatgg gcggcaatac caactgcgta
     1081 aaactgcacc cgatggagga ttcgaaaggt aatgctgact ggcgggcaat caacaacaac
     1141 cgtcagcaga tttttcgctg gctacgtggt gagacgaaag cggcaagaat caaaactaaa
     1201 gcgctggcca tggcgatgga agctgcattg cctgcggaac gatatgcaca gctgggaatg
     1261 accactcagc agttaatttg cattgcgatt cgtgattttg ccgcagcgat tattgctctg
     1321 ttgcttgatg caagggatcg accccagcgg atagcacagg cattacaagc catacaggaa
     1381 acacagcgcc tgaccagcgt ttaacttgta tcgaggaaag accaatatgc agacatcaac
     1441 agaccgcatc acctggcgga acggctggcg tttaaatggc gaaccatcct gtgcgcatga
     1501 tgtacgtgga atatttgaag aacgcctgtc cgcaaaaaaa tgggaaatct atgagaaacg
     1561 caaagctgag atgatcgaga cgtgcgtttt tctcacacca aaagactacg aaatagcctg
     1621 tcgtgaactg gctgagctgc tggggatctg actatgagca tgaccctaat ggcccgggct
     1681 atggcaataa aaaccggaaa cccaatccgt aaactggtgc tgattaaact tgctgataat
     1741 gccaatgata atggcgaatg ctggccatct tatcagcata ttgctgatca ttgtgaatgc
     1801 agcaggagtg ctgttcgtac gcacattgac gcgcttattg gcatgggcgt tttaacaaaa
     1861 gaaaaccgca tgggtataaa caatggtaag ggcaatacgt cgaatgtgta ttacctgaat
     1921 cttgataccc ctgtgccacc aaaaagcaca gcccctgtgc cgtcaaaaat cacaggtatg
     1981 ccgttagaaa acacaccccc tatgccatgt ggtggcacca gaaccagtca ctcttttgaa
     2041 ccagtcaatg aacctaatga tccccctaac ccccaaaagg gggagggtga cgaattgatc
     2101 ctagctgacg ctaaaaaagc cctggaattc tacaacgaac aaacaggtac ccgctgccgt
     2161 gatgttaagc cgttcattcc gatgcttacg ccgacacaaa cacgggaggc atacacactg
     2221 gctgaactgc agttagttat tcgttgggtt ctggcgacat ggcgccgccg tggttctggt
     2281 ttaccaaaac cttccaatat ctgccgcgtt aatcgctttg atggttatct cgctgatgcc
     2341 gaagcatggg ccactacgga ggctgatgtt gatccggatg ccgtcatgaa cggctacaac
     2401 gagatattcg ctgacacact gcctgctgct gaactggatg cagatcgccg caggatgatt
     2461 attcgcctgg cagcccatat gaaaaataaa actacgggag cattcctggg ttacttcgaa
     2521 aaattccgag ctgatgcccc cgatttttat ttcggttcta acggtggatg gcgcgccagc
     2581 tttgactatt tgatgaaacc agaaacttta cgtaataccc gggaaggttc gctatgactc
     2641 cgcaggaact ggaagcgtgt gtgctggcag ggttgctgaa tggcggtgct acacctgacg
     2701 catttgacgt gatcgcatcc acgccagagg aatcattcag cattggtttt tatcgccgtg
     2761 cattcagcga gataaaaaaa caggcactga ctaacggcat gatcgacatg cttttcatca
     2821 gtgaagcgct gggcggttca agtctggctg atttgtcgga aatttcccgc atacctgcaa
     2881 cgattccgaa tctcaaaggg tatgcaggga agatggttaa ggcatggcgc agccgtgcgc
     2941 tggcgaaact tttgcaggat ggcgccgacg gcatccgcaa tgcagccaac caggaacaac
     3001 gtgatcaggt tgtggaaaag gctgtggcgc agctgctgga tatgaccgct gaaagcggcg
     3061 acgttcaacc ggtacacatt aacgagctgt tgcctgccta catggacacc gtacagaaac
     3121 gcatggaagg cgatgaatcc acgcgtaacc ttctgaccgg gattgcggat ctcgataacg
     3181 ctactggcgg tataaaccaa accgatcttg tggtcgtggc aggtcgtcca ggaatgggta
     3241 agacagaatt tgctctgact gttgtggaag gtgttacagc aaaaggcgga ggcgcgctaa
     3301 ttttcagcat ggaaatggct gctgctcaaa ttgttgagcg ctcgctggct ggcgccggaa
     3361 acctgtctgt ttcccgtctg cgtaaccctc aggatatgta cgatgaggac tgggcgcgat
     3421 taacggctgc gataggtgag cttacggatc gtgatatctg gattgtcgat gcaaccgacc
     3481 ttacggttga acagattcgc gctattgccg aaacacacaa acggcgtcat ccacatctgg
     3541 cgatgattat ggtcgactat ctcggactga taaaaaaacc gaaggcggag cgtaacgatc
     3601 tcgctgtagc gcatatttcc cgaaatctta aaacgatggc tatgcgcctg cacacgccaa
     3661 ccttcgcgct gagccagctc tcccgcgccg tcgatgcgcg cccggcggca cagcgccgcc
     3721 cggtaatgtc agatctgcgt gattcaggct ctattgagca ggatgctgac agcattctgt
     3781 ttctgtacag agatgaagtt tataacccag aaagcccagc tgcaggtgta gctgaggtca
     3841 tcctcggcaa atgccgcttt gcagctgctg gtaccgtagt ttaccaggag ttcaaaaacg
     3901 gacactttct gccgatcgat cagcacattg gcaaagaaaa aacacgaatt caactggagg
     3961 cagcaaaacc cagaaaaccg caccgtaaat atgccgagaa gtacaacacc gacgcatttt
     4021 aaaacgcttg accagcgtga aatacaatga ggaaagacca atgaccgatt taatttatcc
     4081 taaagtagcg acagctgacg atgcctgtga ctggacaaac gtaatcatct ggcggatgaa
     4141 cgcaggtgcc agggctcgca gccgttcggt ttacgtacct tgcccgcgtc cggtccctgt
     4201 tccggggtta actgctcgca cggccccaaa aactaaaaag tcaaaacctg ttgaaaccaa
     4261 cccacgctgt ttcagtaaga cgcataccgg aactgttatt tactcaggag gagagaagac
     4321 cgtaaaactt cgcgaaacgg caactgtatg gacttctggt agcaaagaga attacgacaa
     4381 aaaaacaggg tacagagttg ggattaagag tcgttgcaga cttttgcttg attccattaa
     4441 acccattgcg aatcccactg aatccccatt accccaaaaa tccagcgagc tgccggctga
     4501 atacctggtg gcgattatga agggtaaaac gctctcatat caggggatca tgtcagcgat
     4561 taaaaaatat tacccggaca tcaaaataag tctggagcaa ctacagaaac gcgtctttgc
     4621 gctttgcatg tcgaactttg ttggcattga gcggcatgac gacatgcccg ttacacactt
     4681 cacgcttaaa agcgttgatc cccgtttcta cgttcactca gagaaaaaca tgagggctta
     4741 aggcatgacc gggcaatcgg attacctccc gcccggtctc ccgctcaatc gtgcgaaatg
     4801 gccgcaagaa taccaactca aggagcatta cgatatgcgc gctgccgcgc tcgttcgtca
     4861 gctctatgag cggaaagtta ctcgtcagac ggttattcag cacattgatg caacgccgga
     4921 gagttatcgg gagtttttca gacaacgttt gaattactgg agagttacat atgaggtgac
     4981 tgcacggaat aaataataag acatggctag caattcaatt tatgctaacc atgtttaaat
     5041 tatgggtgcg ttattactga acgatgttct ttacctttaa gtgcttcaat tatgaactga
     5101 atctgtttat ttgtggtttt ttctaaaatg tcaatgttaa ataattccgc ataactatca
     5161 cgttcagtac atggaccaga aagtagtggg tgaagtcttt ttttgcaccc gctattagta
     5221 ttttctttag gtttgccaat aacatctaaa agtaaacctt caagacacgg ttgcgacccg
     5281 acaagattta ttccagcgga tatcgctctt tctttatatg ttttaggcca acaaagatca
     5341 gtatcgagaa gaacaatgac aaaatcatat ccatcgcaat tcttacatga aattgcgtga
     5401 gttattatat gctcaggccc ctttccacca gcagtaataa ctgtaacttt aaattttcca
     5461 tttgaaaata aggatttcag atgggaaaga aaagcttttt ccgcatatcc ttccccaact
     5521 aatagcagag ttttattaat ggtgcgccgt acaactttct ttttagccat ttcaaattcc
     5581 ctttgtagct tagatattaa tattaggtac gccgcctaac gcgccagtaa tatatttagc
     5641 atacaaatta tcttgacttc ttaaaccctg aatgtcatca agacgccatg cctcgctaat
     5701 gctgtttgat ttttcaacta aataaacatt atgttttttc aatgatttaa gtatttctgc
     5761 tgtgtgacag ctaaaaatca attgtgacga ttgtttattt attccatcat ttgcaaacat
     5821 atctaataat tcgcggatca tataagggtg gaggtcactg tccaattcat ctataacggc
     5881 cacaccacca taatgcagcg cggatatcaa cttgtaaata aagtaataac acgcttgagt
     5941 accagtggac tccataatga atggtacttc aaattcctgg ccgtcatgta tatgaatgcc
     6001 ataaggtaaa actcgagttt ctgtttcacc tgtcttttta tcaattatct cttctttttt
     6061 tattttaata tcttttaaac caaaatccat tctggttaga tatttcttcg ctttttcaaa
     6121 aatttctggg tcttcttcat aacattctgt agcatctaaa actttaccat
//
LOCUS       DAJVKX010000193         6095 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.193, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000193 DAJVKX010000000
VERSION     DAJVKX010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6095
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.193"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(118..606)
                     /locus_tag="OPY25_004223"
     CDS             complement(118..606)
                     /locus_tag="OPY25_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004889762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0929681.1"
                     /translation="MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQVTGASRTF
                     VCCGSDSDVLAYYSLASSAVTTNTAPGRFRRNMPDPIPVVVLGRLAVDRSLHGQGVGR
                     ALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLV
                     HA"
     gene            complement(603..896)
                     /locus_tag="OPY25_004224"
     CDS             complement(603..896)
                     /locus_tag="OPY25_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCS0929682.1"
                     /translation="MPVANSMAMKRETLNLRIKPAERDLIDRAAKARGKNCTDFVLEA
                     ARAAAEEALIEQRIIMADPEAYQAFLIRLDQAPAPNDALRKTMQTPAPWEQEK"
     gene            complement(1323..2336)
                     /locus_tag="OPY25_004225"
     CDS             complement(1323..2336)
                     /locus_tag="OPY25_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCS0929683.1"
                     /translation="METNITWQQLIDEYFFAKPLRSASEWSYTKVFKSFVHYMGPLSC
                     PNDVTYHKVLAWRRFLLKEKKLSGRTWNNKVAHMRAIFNYGIQRGLLHYDENPFNNSV
                     VKPDKKRKKTLTQAQIEYAYQIMEQYENQENTGLGLKYSRCALFPAWFWLTVLDTLYY
                     TGIRQNQLLHIRLNDVDLREGQIRLITEGCKNHKEHYVPVISFLRPRLTCLMEKAQSE
                     GLKGNDRLFNIALFTGKDPAIGDDMDSPQVRAFFRRLSKECQFAISPHRFRHTLATEM
                     MKMPEQNLHMAQSVLGHSNMKSTLEYVENDIAVMGRALEAQFMQIKAAHARSIYSGLT
                     KNR"
     gene            complement(2500..4089)
                     /locus_tag="OPY25_004226"
     CDS             complement(2500..4089)
                     /locus_tag="OPY25_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraI domain-containing protein"
                     /protein_id="HCS0929684.1"
                     /translation="MFRKVKSWMEKKNFRQIEENKSGNAKKRLIPCTDGYFNPAAISD
                     LLQHERRQQWLRILWENSALPKERFERYFLLPLHGVVGLCQRLPASAQGKFAYTDGMV
                     DYVIQTTVFAVRLSKGYMLPRGASAEEQSAQSVSWSAVVYYAALFHSLGRLWNIEGEL
                     RSGAVWRPGLSVPEEPYRFRFKAEPDIAGAQVYGELIALRFLPEPVLQWLGKNPDILR
                     TLLAFISGRYSDAMDITDIVNEAIVHAGGIPLGFPIAQEEQTSELAEILNPAATVAPV
                     LRKGSSTTPPDVPVMVDGGQETTVLLSSLDSDAKPERGEGQPTAETDPDVLQVMSILG
                     GLTNTDTQSPEKEGVNTETDMVAGESFPEVAVALETSAAEEVINDTVTTECTGSSSGG
                     ISSLSSTELGDLFWSWLRDGLREGDIPVNTADACVHLTCGFVFISVPGVFFLFLKSHS
                     RSCSSGLKESGRKEQVQAAFEKMRKHRVSDSRRFWQCCLYEEPGGRGRYKKLTGYLIK
                     MSEIYANGNFPDDSLFLKVIN"
     gene            complement(4073..5584)
                     /locus_tag="OPY25_004227"
     CDS             complement(4073..5584)
                     /locus_tag="OPY25_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCS0929685.1"
                     /translation="MPHTDTPEQAAVIAWKGERLVVCAFAGSGKTTTLRRYAEENPTE
                     RMLYIAYNRAIRDEAEQKFPFNVTCKTSHQLAWPTVGKHYSHRLINSLRLTYVARALN
                     SRNWLLARLTLDVLNRFICSAATDITPEHMPDPDDCKGLQPGQILFSAKKIWAMMSAR
                     QGDFPVTHDTYLKLYQLSKPNLSSRYTTLLFDEAQDANPVISAIVLNQTCRVVLVGDT
                     HQQIYRFRGADNAMQAPQLENSDRLWLTHSFRFGPEVAGVANRLLALKGETHQITGKG
                     GAGRVLLTMPRNFGHHAVLHRSVCGVIRTALHWSLAGRKVFWVGGMESYRIEDLLDLY
                     WFSIDMSERMRHDRLTREYRDYDEYLQIAEDTGDVEMKQGIFILEQFFPLPDRLNTLR
                     EQRVISESEADVTVCTAHRSKGLEWDRVKLHDDFLDILDPDMPESQRQDEINLMYVAA
                     TRARKVLITDPILHELLIQPRAEDIAGTSADKSGESEVSTENDKKGTEYVPES"
BASE COUNT         1608 a         1590 c         1318 g         1579 t
ORIGIN      
        1 tcacattaaa cactgaagat acctgatgac ttcagacagc ggacatgccg agcaacaata
       61 tatcattgat aatttgattc ataaaacaac catcttattg gcaccaaata ataccaatca
      121 ggcatgaacc aaatccccca acgtcaccat caacatcatc ggatccatcg gcgacggctc
      181 aaaccccacc cgcaggtaaa actcccgcgc ttcatccgac agggcatgga ccagcatccc
      241 gcgaataccg atagtttccg ccacctgaat cacccgcagc ccggcatccc tcaccagcgc
      301 ccgacctacg ccctgcccat gtagcgaccg atccaccgcc agacggccca gcaccacaac
      361 cgggatcgga tcgggcatat tgcgacgaaa gcgaccgggg gcggtgtttg tcgttaccgc
      421 gctggacgcc agcgaataat acgccagtac gtcagaatcg ctgccgcaac acacaaaggt
      481 acgggatgcg ccagttacct gatttttcat cgcccgctgt tttagccagt tatccattga
      541 atccacaccg cagcagaagg gggtaagaat atgcccggca tgaagcggtt caggggcgga
      601 gatcattttt cctgctccca cggtgcagga gtctgcatgg ttttacgcaa cgcatcgttt
      661 ggcgcaggag cctgatccag acggatcaga aatgcctgat aagcctctgg atcggccata
      721 atgatgcgtt gctcgatcag cgcttcctcg gcggcggcgc gggcagcttc tagcacaaag
      781 tctgtgcagt ttttccctct ggcttttgca gcccgatcga taagatcgcg ctcggcgggc
      841 ttgatgcgca ggttcagggt ttcgcgtttc atcgccatac tgtttgcgac tggcatggtg
      901 ttgtcctctt gtgtttctgt ggatattaag tatacaacac gcgtaacgca gatgtcatta
      961 cgatagattt aaagggaatc gaaccagtgc atcgaaccga acaagttttt atacctcaaa
     1021 agccactatt ttgatttaca agtaaaaata cgggtcacgc tcagggtctt gacaattcgt
     1081 caaaaacgga tttatgacgg aattcaattt aatagatagc tgaatgctcc cgagtccggg
     1141 caccactctt atcaaagtac gttggttagg gcttgagaac cttaacggac gttacgtgga
     1201 acccgaaagg acaatcgatg tagcaggtca gtctacacat cgagatggat ttttgggttt
     1261 ctcaagtaag ggaacttgtt ggcgcaagtt cccttttctc gatcacccga tatcgttaca
     1321 gcttatctat tctttgtcaa cccactgtaa atgcttcggg catgtgctgc cttaatctgc
     1381 ataaactgcg cttccagagc cctccccatc actgcaatat cattctccac atactccagc
     1441 gtggatttca tgtttgaatg acccagcaca ctttgcgcca tatgcagatt ctgttccggc
     1501 attttcatca tctccgtggc cagcgtgtgt ctgaaacgat gaggactgat cgcaaactga
     1561 cactccttgg acagacgacg gaagaatgct cttacctgag gagaatccat gtcatcgcca
     1621 atggcgggat ctttgccggt aaaaagtgca atattgaaca ggcggtcatt acctttcaat
     1681 ccttcgctct gcgctttctc cattaaacag gtcagccgtg gacgcagaaa actgatcacc
     1741 ggcacatagt gttctttgtg atttttacac ccctccgtaa tcagccgaat ctgcccttct
     1801 ctcaaatcaa catcattcag ccgaatatgt aataactggt tctgacgtat ccctgtgtaa
     1861 tagagcgtat ccaggacagt gagccagaac catgcaggaa ataaggcgca gcgggaatat
     1921 ttcagtccca gccctgtatt ctcctgattt tcatactgct ccatgatctg ataggcatac
     1981 tcaatctgtg cctgagtgag cgttttcttt ctcttcttgt ccggtttaac taccgaattg
     2041 ttaaacggat tttcgtcata gtgcagtaac cctcgctgta ttccgtagtt aaagatggcc
     2101 cgcatatgcg ccaccttgtt attccaggta cgtccggaca gctttttctc ttttaaaaga
     2161 aaacggcgcc aggcaagcac tttgtgatat gtcacatcat tagggcagct taacggcccc
     2221 atataatgta caaatgattt gaagactttg gtgtaactcc attcagatgc tgagcgcaga
     2281 ggttttgcga agaaatattc atctatcaat tgttgccagg taatatttgt ttccattttt
     2341 atcaccgcta ttgagctttt attattaata cacacacagc ttgtgtggat ttaaattccc
     2401 gtaatttcat gcacatgaca acggaaaaat atttcaattt gttacaggaa ctgatggttt
     2461 tttaagactt ttcttatatt tattttgtta cattttattt caattgatga cctttagaaa
     2521 taaactgtcg tcgggaaagt taccattagc ataaatctct gacattttta tcagataccc
     2581 tgttaacttt ttgtatctcc ccctgccccc tggctcttca taaagacagc actgccagaa
     2641 tcgccgggaa tcactgaccc gatgctttcg catcttctca aatgccgcct gcacctgctc
     2701 cttcctcccg ctttctttca gaccagaaga acaggaacgc gaatgtgatt tcaaaaacag
     2761 aaaaaaaaca cccgggacgc tgataaatac gaagccacaa gtcagatgaa cacaggcatc
     2821 agcagtattt actggtatat ccccctcacg aagcccatcc cttagccagg accagaacaa
     2881 atctcccagc tccgttgagg aaagcgatga tatgccaccc gaggatgatc cagtgcattc
     2941 agtggtaacg gtgtcattga taacctcttc tgctgctgaa gtctcaagtg caaccgcgac
     3001 ttccggaaac gattctcctg ccaccatatc ggtctctgtg ttcacgcctt ccttttcagg
     3061 cgactgtgtg tcagtgttcg tcagccctcc cagaatcgac atgacctgaa gaacatctgg
     3121 atctgtttca gcagtaggct gcccttcccc acgttcaggc ttagcatcag aatcaaggga
     3181 agataaaagg acagtagtct cctgccctcc atcaaccatg acagggacat caggaggagt
     3241 tgtagaagaa cctttcctca acacgggagc tactgtcgcg gcagggttta gtatctctgc
     3301 taattcagaa gtctgctctt cctgtgcaat gggaaaacca agaggtatcc ctccggcatg
     3361 cacaatggcc tcattaacga tatccgtaat atccattgca tcactgtaac gtccgcttat
     3421 gaaagccagc aatgttctca gaatatcagg gtttttaccc agccactgaa gaaccggttc
     3481 tggcaaaaat ctgagagcga tcaattcacc ataaacctga gcacctgcta tatcgggttc
     3541 tgctttaaaa cgaaaacgat aaggttcttc cggaacactt aatcccgggc gccatacagc
     3601 accactacgg agctcgcctt caatattcca taagcgcccc aacgagtgga ataatgcagc
     3661 gtaataaacg acagcactcc agctgactga ctgcgcggat tgttcctctg cagatgcacc
     3721 tcggggcagc atatatcctt ttgataaacg tacggcaaag accgtcgtct gtatgacgta
     3781 atccaccatg ccgtctgtat aggcaaattt tccctgagcc gaagccggga gtctctgaca
     3841 taaacccaca acgccgtgta aagggagtaa aaaataacgt tcaaaacgct ctttaggtag
     3901 cgcgctgttc tcccacaaaa tccttaacca ttgctgccgt cgttcatgct gtaacaaatc
     3961 tgaaatggcc gcagggttaa aatatccatc cgtacaggga ataagtctct tcttcgcatt
     4021 tcccgattta ttttcttcta tctgtctgaa gtttttcttc tccatccatg acttaacttt
     4081 ccggaacata ttcagtccct tttttatcgt tttctgtact cacttctgac tcacccgatt
     4141 tatccgcaga agttccggct atatcttcag cccggggctg gatcagaagc tcgtgcaata
     4201 tcggatcggt tataagcact ttacgcgccc gggtggctgc cacatacatg aggttaattt
     4261 catcctgccg ctgactttcc ggcatgtcag gatccagaat atcgagaaag tcatcatgta
     4321 acttcaccct gtcccattcg agccccttac tcctgtgtgc tgtacatacc gtcacatcag
     4381 cttcagattc actgatgacg cgttgctcac gtaacgtatt cagtctgtcc ggtaacggaa
     4441 aaaactgttc aagaataaat atcccctgct tcatctccac atcaccggta tcttcggcta
     4501 tctgcagata ttcatcatag tcccggtatt cacgggtcag cctgtcgtgt cgcatacgct
     4561 ccgacatatc aattgagaac cagtacagat ccagtaaatc ctcaattctg tagctttcca
     4621 taccaccaac ccagaatact ttcctgccag ccagcgacca gtgcagtgcc gtccggatga
     4681 caccacagac agatcggtga agaacagcat gatggccaaa attccgcggc attgtgagca
     4741 gaacacggcc tgcgcccccc tttccagtta tctgatgcgt ttcgcccttc agggccagca
     4801 gcctgttggc caccccggct acctccggac cgaagcgaaa gctgtgggtt agccaaagac
     4861 ggtctgagtt ctccagttgc ggagcctgca tggcattatc cgccccacga aagcggtaga
     4921 tttgctgatg agtatctcca accagaacta cccggcaggt ctggttgagc acaatggcgc
     4981 tgatgacagg attggcatcc tgagcttcat caaacaataa cgtggtatag cgggaagaaa
     5041 gattcggttt gctcaactgg taaagcttta gataagtatc atgggtgacc ggaaaatccc
     5101 cctgacgggc cgacatcatt gcccagattt tctttgctga aaacaggatt tgacctggtt
     5161 gtagcccctt acagtcgtca ggatcaggca tgtgttcagg cgtaatatcg gtggccgcgc
     5221 tgcatataaa gcgattcaga acatcaagcg tcagtctggc cagcaaccag ttgcgggagt
     5281 ttagcgcccg ggcgacatag gtcagtcgta gtgaattaat cagacgatga ctgtaatgtt
     5341 tcccgaccgt cggccaggcc agttgatgcg atgttttgca ggtaacgttg aaggggaatt
     5401 tctgctccgc ctcatcccga atggcacggt tataagcaat atagagcatt cgttccgttg
     5461 gattttcctc agcataacga cgaagtgtgg tggttttgcc actcccggca aaagcacaga
     5521 caaccagacg ttcgcccttc catgcgatga cagcagcctg ttcaggagta tcagtgtggg
     5581 gcataatcgg gctccggata aaagcatttt gctcatcctg agaacccgcc agactgttat
     5641 ccagtgcaat ttataaatcc aaaaaaaaga attctgcaaa ccagccctgt accatcaagt
     5701 tcatatcctc agcggaggaa atgcgtgaaa tccagcgcaa cacacggagt atcacccact
     5761 acccaggcat catgattctc agaaacctca aatgcttcgc cggcatgaat aaggtattca
     5821 tttccgaagc agtcacgcac catcatttca ccggaaatta taaaaccagt atgacgttct
     5881 gacggttttc cggtcattat taatgggtga ctctaatgca aacatctagc gagaaaatat
     5941 tttgtagaca tcgtcaacgg aaaagttaac taacaatagt cattatccat atctttaatt
     6001 tgaaatggaa acagggcaaa gagtaattaa aatacagcct gtgattctgt acagttaagg
     6061 tttaacccca aaggtgcaaa caattaaatt tgtaa
//
LOCUS       DAJVKX010000194         6063 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.194, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000194 DAJVKX010000000
VERSION     DAJVKX010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6063
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.194"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            112..648
                     /locus_tag="OPY25_004228"
     CDS             112..648
                     /locus_tag="OPY25_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HCS0929686.1"
                     /translation="MSMKKYLAMITGSLLVSSSAMAVSDNTITFQGEVSDETCSVVIN
                     GNQAKPVVLLPTVSTKELSEQGKTAGPITFDIGLSGCTGSKDKTTKISTVFVGNQVTS
                     NGNLGNTGSAKNVEVQLLDTSGEPINLTGGFTGDGDLQLEPNASEASATYTARYYSTG
                     KAEAGTVAATLQYAVSYK"
     gene            710..1471
                     /locus_tag="OPY25_004229"
     CDS             710..1471
                     /locus_tag="OPY25_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HCS0929687.1"
                     /translation="MKMDTRHSALYYLIVFLLLALPATASWASVTILGSRIIYPSTAS
                     SVDVQLKNNDAIPYIVQTWFDDGDMNTSPENSSAMPFIATPPVFRIQPKAGQVVRVIY
                     NNTKKLPQDRESVFWFNVLQVPPTNIGSDSGKNKMLVMLRSRIKLFYRPDGLGKPDNL
                     AKKLQIKTVNKGSGKSGIVIVNPQPWFASLSNLNVKVNGASYNLDADMIAPFSSQTWW
                     LPGKRSLKSFSGTVTVTLVNDLGARISESYDVPHH"
     gene            1455..4016
                     /locus_tag="OPY25_004230"
     CDS             1455..4016
                     /locus_tag="OPY25_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein"
                     /protein_id="HCS0929688.1"
                     /translation="MSPTINLNRKSLALLIAIVCSGSAQGEEYYFDPALLQGATYGQN
                     IARFNEQQTPSGDYLADVYVNGTLVASSTNIRFNAVKEGQQAEPCLPLSVMKAAQIKS
                     LPETDAATECRPLREWVPHAGWQFDSATLRLLLTIPMTELTHKPRGYISPSEWDSGAL
                     ALFLRHNTNWTHTENTDSHYRYQYLWSGLNMGVNLGLWQVRHQSNLRYANSNQSGSAW
                     RYNSVRTWVQRPVASINSILSLGDSYTDSSLFGSLSFNGVKLVTDERMRPQGKRGYAP
                     EVRGVAASSAHVVVKQLGKVIYETNVPPGPFYIDDLYNTRYQGDLEVEVIEASGKTSR
                     FTVPYSSVPDSVRPGNWHYSLAFGRVRQYYDIENRFFEGTFQHGVNNTITLNLGSRIA
                     QRYQAWLAGGVWATGMGAFGLNATWSNARAEHNERQQGWRAELSYSKTFTTGTNLVLA
                     AYRYSTNGFRDLQDVLGVRREAKTGIDYYSDTLHQRNRLSATVSQPLGRLGTLNLSAS
                     TADYYNNQSRITQLQMGYSNQWRNISYGVNIARQRTTWDYDRFYHGVNEPLDVSSRQK
                     YTETTMSFNVSIPLDWGENRTSVAMNYNQSSQSRSSTVSMTGSSGENSDLSWSVYGGY
                     ERYRNSNSDSSAPTTFGGNLQQNTRFGALRANYDQGDNYRQEGLGASGTLVLHPGGLT
                     AGPYTSDTFALIHADGAQGAIVQNGQGAVVDRFGYAILPSLSPYRINNVTLDTRKMRS
                     DAELTGGSQQIVPYAGAIARVNFATISGKAVLISVKMPDGGIPPMGADVFNGEGTNIG
                     MVGQSGQIYARIAHPSGSLLVRWGTGANQRCRVAYQLDLHTKEPFLYLNKICEKE"
     gene            4021..5346
                     /gene="stbD"
                     /locus_tag="OPY25_004231"
     CDS             4021..5346
                     /gene="stbD"
                     /locus_tag="OPY25_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher protein StbD"
                     /protein_id="HCS0929689.1"
                     /translation="MLFSFRTLLFITSLFVSAGTWSSCIKVTDKSALSDAAIKAGYTA
                     QNWIGALDTNTGNIGLPTVISISNSETFQPSGTLLASGIGNFLTAATGTPYSSKQVLY
                     RCDSADAGKLYEMYSTNGDSAFAGAFFTPEVEGAYYDVERNVAVRMTNLSTGEYYSRF
                     WKERQLTADSWFQDDKYIYIPASAFSNVLYEMFKIDSRKYFAYQNPMDRDTWTQPRGY
                     IAFKGPGLITERIKAGLDHASDYYGWPSYWPGAWSTYNSVTYVRGALCKITDYPAIVK
                     IPPVAVGILAAGGNSQAPFHVSLECESGAVSSALPSTSAANVAMGFVVNQPTAVAAAR
                     RLGLTTSAGGLSWLLDTHYGEPGVASGVGIRIYNDAGTPINLLPDRIKTGTGNARGWY
                     GYKDLTTRVSSGSVETYSGDFTASLEALGGQTVTAGSVNAQLQAVVSFQ"
     gene            5312..>6063
                     /locus_tag="OPY25_004232"
     CDS             5312..>6063
                     /locus_tag="OPY25_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial assembly chaperone"
                     /protein_id="HCS0929690.1"
                     /translation="MRNYRQWLVFSKVILTLLGLTGWYGPAQAAVNIDRTRIIFASDE
                     VAQSLTLSNDNTTPMLLQVWTDAGNIDASPDNSKTPLVALPPVFKMQPGELRTLRLLL
                     SSRQQLATDRESLFWLNIYQIPPVTQDIKNHPRKLVLPLRLRLKILIRPTGLKAPTEA
                     EEKKLRFIAKENTIRIVNPTSWYMSLTLTMDNKKSIGDIMVAPKTALDVPLTRSPTPG
                     ASINYAVINDSGNWRQYTAILEKYISKSNFIP"
BASE COUNT         1579 a         1550 c         1525 g         1409 t
ORIGIN      
        1 caaaaataga gttaatgatc gttattttta ccactcctcc ataagcacga aacattcggg
       61 cgaattgcac tcgtcctgaa aaagtaaaga ttaatacagg aacattatta tatgtctatg
      121 aaaaaatatt tagcaatgat cacaggctcg cttcttgtct ccagcagcgc gatggctgtt
      181 tctgataaca ccatcacctt tcaaggggaa gtctctgatg aaacgtgctc tgtcgtgatt
      241 aatggtaatc aggctaaacc cgtcgtgtta ttgccaacag taagtactaa agagttatca
      301 gaacaaggga aaaccgcggg gccaataacg tttgatattg ggctgtccgg gtgtaccggt
      361 tctaaggaca aaacaacaaa aatttccacc gtctttgtcg gtaatcaggt caccagtaac
      421 ggtaacctgg gtaatactgg cagcgcgaaa aatgttgaag tccaattact cgacacttca
      481 ggggagccaa tcaatctgac cggcggcttt actggcgacg gcgacctaca gctggaacca
      541 aatgcttctg aagcgagcgc gacttatacc gcgcggtatt actctaccgg gaaagcagag
      601 gctgggacag tcgctgccac cctacaatac gccgtttcgt ataaataatt gtcgctacgg
      661 tctggcattg aaacgccaga ccattttcaa tcgccaggga gttgttgaga tgaaaatgga
      721 tacccgacat tccgcattat attacttaat agtttttcta ttgctggccc tacccgccac
      781 agcatcgtgg gcgagcgtta ctattttggg tagccgaata atttacccat caacagcctc
      841 ctccgtagat gtgcagttaa aaaataatga tgcaatacct tatatcgtac aaacctggtt
      901 tgatgatggc gatatgaata ccagcccgga aaatagcagc gcgatgccgt ttattgccac
      961 gccgccagta tttcgtattc aacccaaagc aggccaggtg gtacgcgtaa tttataacaa
     1021 cacaaaaaaa ttgccgcagg atcgtgaatc agtattctgg tttaacgtat tacaggtgcc
     1081 accaacgaat attggcagcg acagcgggaa aaataaaatg ttggtgatgc tacgctcaag
     1141 aataaagctt ttctatcgtc ctgacgggct aggtaaacct gataatctgg cgaaaaaact
     1201 acagattaaa acggtaaata agggttctgg aaaaagcggt attgttatcg ttaatccgca
     1261 gccctggttt gcctctttaa gtaacctgaa tgtaaaagtg aacggcgctt cgtataacct
     1321 ggatgcagac atgattgccc ctttttccag tcaaacctgg tggctgccgg gcaaacggtc
     1381 actcaaatcc ttctccggta cagtcaccgt tactttggtt aacgacctgg gcgcaaggat
     1441 aagcgagagc tacgatgtcc cccaccatta atttgaaccg caaaagcctt gcgctattga
     1501 tcgccatagt ttgctcaggc tccgcgcagg gtgaagagta ttattttgat cctgcgctac
     1561 ttcagggggc cacttacgga caaaatattg cccgttttaa tgaacagcaa acgccttccg
     1621 gagactatct tgccgacgtt tacgttaatg gcacgctggt agcctcgagc actaatattc
     1681 gatttaatgc tgtaaaagag ggtcaacagg ctgaaccctg cctgccctta tcggtgatga
     1741 aagcggcaca aataaaatca ctccccgaga ccgacgctgc gaccgagtgt cgcccgctca
     1801 gggagtgggt acctcatgcc ggctggcaat ttgatagcgc cacgcttcgc ctgttgctga
     1861 cgattccaat gaccgaactt acgcacaaac cgcgcggtta tatctcccct tcagagtggg
     1921 atagcggcgc gctggcgctg tttttacgcc ataacacaaa ctggacccac accgaaaata
     1981 ccgatagcca ttatcgctac caatacttat ggagcggttt aaacatgggc gttaacctcg
     2041 gactttggca ggtccgtcat caaagtaatc tgcgctatgc caatagcaac cagagcggaa
     2101 gcgcctggcg ctataatagc gttcgaacct gggtgcaaag acctgtcgca tctattaaca
     2161 gtatcctgtc gctgggcgat agctatacgg actccagctt attcggcagt ctgtccttta
     2221 acggagttaa gcttgtcacc gacgagcgga tgcgccctca gggcaaacgc ggttatgcgc
     2281 cggaagttcg gggcgtagcg gccagtagcg cgcacgtggt agtaaaacaa ctggggaaag
     2341 tgatttatga aaccaacgtt ccgccgggcc cattttatat tgacgatctg tacaacaccc
     2401 gttatcaagg cgatctggag gtagaggtta tcgaggccag cggtaaaacc tcacgtttca
     2461 ccgtgcctta ttcttccgtg ccggattcgg tacgtcccgg taactggcac tattcgctgg
     2521 ccttcggcag ggttcgtcag tactacgata ttgaaaatcg tttctttgag ggaacgttcc
     2581 agcacggcgt taataacacc attaccctca acctcggttc acgaattgcg cagcgttacc
     2641 aggcatggct ggcgggcggc gtctgggcca ccggtatggg cgcgttcggc cttaacgcca
     2701 cctggtcgaa tgcgcgcgca gagcataacg agcgccaaca aggctggcgc gcggaactca
     2761 gttacagcaa aacgtttacc accggcacta acctggtact ggcggcttat cgttattcaa
     2821 ccaacggctt tcgcgatctt caggacgtgc tcggcgtacg ccgggaagca aaaacgggga
     2881 ttgattacta ctccgacacg ctgcatcaac gcaatcgcct gtccgcgacg gtaagccagc
     2941 cgttaggacg gcttggcacg cttaacctca gcgccagcac cgcagactac tacaataacc
     3001 aatcgcgtat aacacagcta caaatggggt atagcaacca gtggcggaat ataagctacg
     3061 gggtgaatat cgcgcgacag cgcaccacct gggattacga tcgcttttat cacggcgtta
     3121 acgaaccact ggacgtgagt agccgacaaa aatataccga aaccacaatg tcgtttaatg
     3181 tctctatacc gctggattgg ggcgaaaaca gaacgtctgt cgctatgaat tataaccagt
     3241 ccagtcaaag ccgttcctca accgtatcca tgaccggcag tagcggtgaa aacagcgacc
     3301 tgtcatggtc ggtttatggc ggctacgagc gttatcgcaa tagtaatagc gatagcagcg
     3361 cgccaacgac gtttggcggt aatctacaac aaaacacccg gtttggcgca cttcgcgcca
     3421 actatgacca gggtgataac tatcgtcagg aaggactggg cgcgtccggc accctggtac
     3481 tccaccctgg cggtctgacg gctggcccct ataccagcga tacctttgcg cttattcatg
     3541 ccgatggcgc gcagggcgcg atcgtacaaa atggccaggg cgctgtggtt gatcgctttg
     3601 gttacgccat tctgccttcg ttatctcctt accgcatcaa taacgttacg ctcgacaccc
     3661 gtaagatgcg cagcgatgcc gaactgacgg gaggaagtca gcagattgtg ccctatgccg
     3721 gcgccatcgc gcgtgtcaat ttcgccacta tcagcggcaa agcggtgctg atctccgtga
     3781 agatgccgga tggcggcata ccgccaatgg gcgctgatgt tttcaacggt gaaggcacaa
     3841 acatcggcat ggtcggccag agtgggcaga tttatgcccg aatcgcccat ccgtcgggtt
     3901 ctctactggt gcgctgggga acaggggcaa accagcgttg ccgggttgcc taccaactcg
     3961 atcttcacac caaagaaccg tttctctatc tgaacaaaat ctgcgagaag gaatagcaca
     4021 atgcttttta gtttccgaac gctcttgttt atcaccagtc tgttcgtcag cgccggaaca
     4081 tggtcgtcat gtataaaagt caccgataag agcgcgctct ctgacgcggc gataaaagcg
     4141 ggctacacgg cgcaaaactg gatcggcgca cttgacacga atacgggtaa tatcggtttg
     4201 ccaacggtga ttagcatcag taatagtgaa acatttcaac cctccggcac actattggcc
     4261 agtgggatcg gtaacttcct gacggccgcc accggaacgc cctattccag taaacaggta
     4321 ctttaccgct gcgattccgc cgatgccggg aagctctatg agatgtattc gacaaatggc
     4381 gatagcgctt ttgcgggggc attttttact cccgaagtag aaggcgccta ttatgatgtg
     4441 gagcgtaatg tcgctgtccg tatgacaaac ctcagtaccg gcgaatatta cagccgcttc
     4501 tggaaagaac gccaacttac cgcagacagt tggtttcagg atgacaaata tatttatatt
     4561 cctgccagcg cgtttagcaa cgtgttatat gagatgttta aaattgactc aagaaaatat
     4621 tttgcctacc agaatccaat ggaccgagat acctggacgc agcctcgggg ttatatcgcg
     4681 tttaaaggcc caggcttgat taccgagcgg atcaaagcgg gactggatca tgccagcgat
     4741 tattatggct ggcccagcta ttggcccggg gcatggagta catataatag cgtcacctat
     4801 gttcgcggcg cgttatgtaa aatcacagat tatcctgcga tcgtgaaaat tccccctgtc
     4861 gccgtcggca tattagccgc cggaggcaat agtcaggcgc ctttccacgt cagcctagaa
     4921 tgtgagtccg gtgccgtgtc cagtgccctc ccgtccacca gcgccgctaa tgtcgcaatg
     4981 gggtttgtcg ttaatcaacc caccgccgtg gcggcggcgc gtcgcctggg gctaaccaca
     5041 tctgcaggcg gtctgtcgtg gctactggac acccattatg gcgaacctgg cgtagcttcc
     5101 ggagtgggta tccgcatcta taacgatgcc ggtacgccga ttaacctgtt acccgatcgg
     5161 atcaagacag gcactggcaa cgcccgaggc tggtatggct ataaagattt aaccacacgg
     5221 gtatcatccg gttcagtaga aacctatagc ggtgatttta ctgcctcgct tgaggcgctc
     5281 ggcggacaaa cagtaacggc aggaagcgtg aatgcgcaat tacaggcagt ggttagtttt
     5341 cagtaaagtc atattaacgc tacttgggtt gacgggatgg tatggcccgg cacaagctgc
     5401 cgttaatatt gacagaaccc gaattatttt tgcttcagat gaggtcgctc aatcgttgac
     5461 attatccaac gataatacaa cgccgatgct gttacaggta tggaccgacg ccggaaacat
     5521 tgacgcctct ccggataaca gcaaaacgcc gctggtggcg ctgccgccgg tatttaaaat
     5581 gcagccagga gaactgagaa cgcttcgcct gctcctgagt tcccgccagc agctggcaac
     5641 ggaccgggag agtctcttct ggctaaacat ttatcagata ccgccagtca cccaggacat
     5701 taaaaaccac ccgcgaaaac tggtgttacc gcttcgtttg aggctaaaaa ttttaattcg
     5761 cccgactggg ctaaaagcgc ccacggaagc ggaggagaaa aaattacgct ttattgctaa
     5821 agagaatact atacggatag ttaaccccac ctcgtggtat atgagtttaa cgttaacgat
     5881 ggataacaag aaaagtatcg gcgatatcat ggttgcgccg aaaacagcac ttgatgtgcc
     5941 gctaacacgc tcgccaacgc cgggagcatc gataaattat gcagtaatca atgattccgg
     6001 gaactggcga caatataccg ccatactgga aaaatatatt agtaagagta attttattcc
     6061 tga
//
LOCUS       DAJVKX010000195         5919 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.195, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000195 DAJVKX010000000
VERSION     DAJVKX010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5919
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.195"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..388)
                     /locus_tag="OPY25_004233"
     CDS             complement(<1..388)
                     /locus_tag="OPY25_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein CI"
                     /protein_id="HCS0929691.1"
                     /translation="MNLEKGGRGAIERMVEAYGFKTRQALCDHLGISKSTLATRYMRD
                     SFPAEWVIQCALETGTSLNWLTTGHGSKQTSGNTNTMEVAKYVLSDGALREDGFYIFD
                     KGFLPSTFKKPFVITDNNSEFICDKEF"
     gene            514..735
                     /locus_tag="OPY25_004234"
     CDS             514..735
                     /locus_tag="OPY25_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HCS0929692.1"
                     /translation="MRPNISITLTTPHVTIERYSELTGLSIDTINDMLADGRLICHRL
                     RKDKKREKVMINIAAMTVDALSECNLNLN"
     gene            768..1277
                     /locus_tag="OPY25_004235"
     CDS             768..1277
                     /locus_tag="OPY25_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory CII family protein"
                     /protein_id="HCS0929693.1"
                     /translation="MFDYQVSKHPHFDEACRAFALRHNLVQLAERAGMNVQILRNKLN
                     PAQPHLLTAPEIWLLTDLTEDSTLVDGFLAQIHCLPCVPINEVAKEKLPHYVMSATAE
                     IGRVAAGAVSGDVKTSAGRRDAISSINSVTRLMALAAVSLQARLQANPAMASAVDTVT
                     GLGASFGLL"
     gene            1285..1581
                     /locus_tag="OPY25_004236"
     CDS             1285..1581
                     /locus_tag="OPY25_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2724 domain-containing protein"
                     /protein_id="HCS0929694.1"
                     /translation="MLTKEPSFASLLVKQSPAMHYGHGWIMGEDGKRWHPCHSQDELL
                     SELTTRKRRKSKCMQRKVKWFISFVTEGRVIQYLKMICSVVIRRCRAMAVTFSR"
     gene            1699..2040
                     /locus_tag="OPY25_004237"
     CDS             1699..2040
                     /locus_tag="OPY25_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5347 domain-containing protein"
                     /protein_id="HCS0929695.1"
                     /translation="MAINGAAATVPLSPGERLNGLNHIAELRAKVFGLNIESELERFI
                     KDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVV
                     SLFPRRLTMPN"
     gene            2108..2341
                     /locus_tag="OPY25_004238"
     CDS             2108..2341
                     /locus_tag="OPY25_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 domain-containing protein"
                     /protein_id="HCS0929696.1"
                     /translation="MRNIETLSTKTGPDDAGLNILLTEARLEERRARAEAMVARLDSL
                     ACHITSRQLTHVEAAELLRVTAEAIQNEAQEIH"
     gene            2341..2568
                     /locus_tag="OPY25_004239"
     CDS             2341..2568
                     /locus_tag="OPY25_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HCS0929697.1"
                     /translation="MADAMDLVQQRVEEERQRHIRAARAKTPGVSRVLCIECEAPIPP
                     ARRRAIPGVQLCITCQEIAELKGKHYNGGAV"
     gene            2565..3422
                     /locus_tag="OPY25_004240"
     CDS             2565..3422
                     /locus_tag="OPY25_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HCS0929698.1"
                     /translation="MSTILKWAGNKTAIMSELKKHLPAGPRLVEPFAGSCAVMMETDY
                     PSYLVADINPDLINLYKKVAADCESFISRARVLFEIANREVAYYNIRQEFNYSTEITD
                     FMKAVYFLYLNRHGYRGLCRYNKSGHFNIPYGNYKNPYFPEKEIRAFAEKAQQATFIC
                     ASFDETLAMLQVGDVVYCDPPYDGTFSGYHTNGFTEDDQYHLASVLEYRSSEGHPVIV
                     SNSDTSLIRSLYRNFTHHYIKAKRSIGVSAGESKSATEIIAVSGARCWVGFDPSRGVD
                     SSAVYGVRA"
     gene            3419..5833
                     /locus_tag="OPY25_004241"
     CDS             3419..5833
                     /locus_tag="OPY25_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HCS0929699.1"
                     /translation="MSHADMNNCSGFNEAAAAFSWNSPKKAINPYLDLAEVAPVSALS
                     NLITLYAADNEQEQLRREALSDQVWERYFFNESRDPVQREMEQDKFISRAKLAHEQQR
                     FNPDMVILADVNAQPSHISRPLMQRIEYFSSLGRPKAYSRYLRETIKPCLERLEHVRD
                     SQLSTSFRFMASHEGLDGLLILPEMSQDQVKRLSTLVAAHMSMCLDAACGDLYATDDV
                     KPEEIRKTWEKVAAETLRLDVIPPAFEQLRRKRNRRKPVPYELIPGSLARMLCADWWY
                     RKLWKMRCEWREEQLRAVCLVSKKASPYVSYEAMMHKREQRRKSLEFFRSHELVNEDG
                     DTLDMEDVVNASSSNPAHRRNEMMACVKGLELIAEMRGDCAVFYTITCPSRFHSTLNN
                     GRPNPTWTNTTVRQSSDYLVGMFAAFRKAMHKAGLRWYGVRVAEPHHDGTVHWHLLCF
                     MRKKDRRTITALLRKFAIREDREELGNNTGPRFKSELINPRKGTPTSYIAKYISKNID
                     GRGLAGEISKETGKSLRDNAEYVNAWASLHRVQQFRFFGIPGRQAYRELRLLAGQAAR
                     QQGDKKAGAPVLDNPRLDAILAAADAGCFATYIMKQGGVLVPRKYHLIRTAYEINEEP
                     TAYGDHGIRIYGIWSPIAEGKICTHAVKWKMVRKAVDVQEAAADQGACAPWTRGNNCP
                     LAENLNQHEKDKSADGDTRTDITCMDDKELHDYLHSMGKKEHRELAARLRLVKPKRRK
                     DHKQRITEHQRQQLVYELKSRGFDGSEKEVDLLLRGGSIPSGAGLRIFYRNQRLQEDD
                     KWRDLY"
BASE COUNT         1566 a         1371 c         1526 g         1456 t
ORIGIN      
        1 caaattcttt atcacaaata aattcagaat tgttatctgt gatgacaaaa ggttttttaa
       61 acgtagaggg tagaaatccc ttatcaaaaa tataaaaacc gtcttcacgc aaggcaccat
      121 cagataatac atatttagca acttccatag tatttgtatt acctgaagtt tgctttgaac
      181 catgtccggt tgtgagccaa ttaagcgagg tgcccgtttc aagggcgcac tggattaccc
      241 attctgctgg gaatgagtca cgcatgtagc gtgtggcgag tgtactttta gagattccta
      301 aatgatcgca caacgcctgt cgagttttga atccataagc ttctaccatg cgctctatag
      361 cgcctcgtcc gcctttctcc aaattcatgg tcactccaag tgaactttta tcttgacgat
      421 ttcattgcgc gatcgtatgt ttatggtgtt cacaaaatac aaacgatccg tattcgtcct
      481 gattaatcat cattaaacga ggaatgttgc atcatgagac ctaacatttc aatcactctt
      541 accacgcctc atgtgactat tgagcgctat agcgagctga cagggctgtc catcgatacc
      601 atcaatgaca tgttggctga cggacgcctt atctgtcacc gtttgcgcaa agataaaaaa
      661 cgcgaaaaag tgatgatcaa catagcagcc atgaccgttg atgcgctttc agaatgcaat
      721 ctaaacctta attagttcga ttctgaaata catcagaggc attgaccatg tttgattacc
      781 aagtttccaa acatccacat tttgatgaag cctgtcgtgc atttgcactg cgccacaatc
      841 tggtgcaact ggcagaacgt gcaggcatga atgtgcagat tctgcggaac aagctgaacc
      901 cagctcagcc tcatctatta accgcaccag aaatctggct gcttaccgat ctgactgaag
      961 attcaacgct ggtagatggt tttctggcac agattcattg tctgccatgt gtaccgatta
     1021 atgaggtggc aaaagagaaa ctgccacatt acgtcatgag tgcaaccgca gagatcgggc
     1081 gtgttgctgc aggtgcggta tctggcgatg taaaaaccag tgcaggtcgt cgtgatgcta
     1141 tcagcagcat taactctgta acacgactga tggcgttggc tgctgtttca ttgcaggccc
     1201 gtttacaggc taaccctgcg atggcgagtg cagttgatac cgtgaccggc ctcggtgctt
     1261 cattcggttt gctgtgaggt gcttatgctg acgaaagaac catcatttgc atcgctgctg
     1321 gtaaagcaaa gcccggcaat gcactacggt cacggctgga tcatgggtga ggatggaaaa
     1381 cgctggcatc catgtcattc acaagatgaa ttgctgtctg aattgaccac gaggaaacgg
     1441 agaaagtcaa aatgtatgca gcggaaagtg aagtggttta tcagttttgt tacagagggg
     1501 agagttattc agtacctgaa gatgatttgc tctgttgtta tccgtcgttg tcgggcgatg
     1561 gcagttactt tttcacgcta aaggatggga cgtttttacg gggagagcag gttaaagaga
     1621 cggtacgaaa aaatgtatct ccctttgagc gttaccgtaa gaacaaagaa cgataggtgc
     1681 gtttggggga tatgaagtat ggcaattaat ggcgctgcgg cgactgttcc attaagcccc
     1741 ggagaacgcc tgaatggact taatcacatt gcggaattaa gggcgaaagt atttggcctg
     1801 aatattgagt cagagcttga gcggtttatt aaagatatgc gtgatccacg ggatatcaat
     1861 aacgaacaaa ataaacgggc actggctgcc atattcttta tggcaaaaat tccagctgaa
     1921 cgtcatagca tcagcattaa tgagctgacc actgacgaaa agcgggagtt gattaaagca
     1981 atgaatcatt ttcgtgcagt ggtgagctta tttcccagac ggctaaccat gccgaattaa
     2041 ccaactaatg aaattaatgg cgtaaacccg ccgggcatcc ctttatctaa attcaggaga
     2101 attgattatg cgtaatattg aaaccctctc gaccaaaacc ggaccggatg acgcagggct
     2161 taatatttta ctgacagagg ctcgtctgga agaacgccgg gcaagggctg aagcaatggt
     2221 agctcgcctt gatagcctgg cgtgtcatat cacatcccgc cagctaaccc acgtcgaagc
     2281 ggcagaactg cttcgtgtga ctgctgaagc aatccagaac gaagcgcagg agatccacta
     2341 atggctgatg caatggatct cgtacagcag cgcgttgaag aagaacgcca acgccatatc
     2401 cgtgctgccc gtgccaaaac gccgggcgtg tcccgcgtgc tttgcattga gtgtgaagcg
     2461 ccaattccgc cagcacgccg ccgtgccatt ccgggtgtgc agctttgcat tacctgtcag
     2521 gaaatcgcag agctgaaagg caaacattac aacggaggtg ctgtatgagc accatcctga
     2581 aatgggcggg aaataaaact gccataatgt ccgaactgaa aaaacatctt cctgctggcc
     2641 cgcgactggt tgaacctttc gcgggttcct gtgctgtgat gatggagacg gattatccca
     2701 gctatctggt tgcggatatt aatcctgatt taatcaacct ctataaaaag gttgccgctg
     2761 attgtgaatc gtttatatct cgcgccagag ttttatttga gatcgcaaac agggaggtgg
     2821 cttattacaa cataaggcag gagtttaatt actcaactga aattactgat ttcatgaaag
     2881 cggtatattt cctgtatctc aatcgtcatg gttaccgtgg gttatgtcgt tataacaaga
     2941 gcgggcattt caacattcca tacggtaatt ataaaaatcc gtatttccct gaaaaagaaa
     3001 ttcgcgcatt tgcagagaaa gcccagcaag caacgtttat ctgcgccagc tttgatgaaa
     3061 cgctggcgat gctgcaggtg ggggatgtgg tgtattgcga tccgccttat gacggtacgt
     3121 tttccggcta tcacactaac ggcttcactg aagatgacca gtatcacctg gcatctgttc
     3181 ttgaatatcg atcatcagaa ggtcatccag tcattgtttc taacagtgac acatccctga
     3241 tccgttcgct gtatcgaaat ttcactcacc actacatcaa ggcaaaacgc agcatcggcg
     3301 tgtcggctgg cgagagtaaa tctgcaacag aaatcatcgc tgtttctggg gcgcgctgct
     3361 gggtgggatt tgatccttcg cgtggcgtgg atagttctgc cgtgtacgga gtgcgtgcat
     3421 gagccatgct gatatgaaca actgcagcgg ctttaacgag gccgccgcag cattctcatg
     3481 gaacagcccg aaaaaggcta ttaaccctta tctggacctg gcggaagttg cgccggtttc
     3541 tgcgctttca aacctgatca ctctgtacgc tgccgataac gagcaggaac aactgcgccg
     3601 cgaggcactg agtgatcagg tttgggagcg ttatttcttt aatgaatccc gtgatcctgt
     3661 ccagcgcgaa atggagcagg ataagttcat tagccgggca aagttggcgc atgagcagca
     3721 gcgttttaac ccggacatgg tcattctggc agacgttaac gcccagcctt cccatatcag
     3781 caggccgctg atgcaacgta ttgaatactt cagcagcctt ggcaggccaa aggcttattc
     3841 ccgctattta cgtgagacga ttaagccatg tctggaacgg ctggagcatg tacgcgacag
     3901 tcagctatcc acttcttttc gctttatggc aagccatgaa gggctggacg gcctgctgat
     3961 tctgcctgaa atgagtcagg atcaggtgaa acgcctgtcc acccttgttg ctgcgcatat
     4021 gagcatgtgc cttgatgcag cttgtggcga tttgtatgcc accgatgacg ttaagccaga
     4081 agaaatccgc aagacatggg aaaaggtggc agcagaaacc ctgcgactgg atgtcatacc
     4141 gcctgcgttt gagcaactcc gccggaaaag aaaccgccgt aaacccgtgc cctatgaact
     4201 cattccgggt tcgctggcgc gtatgttgtg cgccgattgg tggtaccgga aattatggaa
     4261 gatgcgttgc gaatggcggg aagagcagtt gcgtgctgtt tgcctggtca gcaaaaaagc
     4321 atctccctat gtcagctatg aagccatgat gcataaacgt gagcagcgcc gtaagtcgct
     4381 ggagtttttc cgttctcatg aactggtgaa cgaagacggc gacacgctgg acatggagga
     4441 tgtggtaaac gccagcagca gcaaccctgc gcatcgccgc aatgagatga tggcctgtgt
     4501 taaaggtctg gagcttatcg cggaaatgcg cggtgactgc gccgttttct acaccatcac
     4561 ctgtccgtca cgtttccatt ccacgctaaa taacggcagg cccaacccga cctggacaaa
     4621 tacgacggta agacaaagca gtgattatct ggtcggcatg tttgctgcat ttcgtaaggc
     4681 gatgcacaaa gccggattgc gctggtatgg cgtgcgggtg gctgagccgc atcatgacgg
     4741 tacagttcac tggcacctgt tgtgttttat gcgcaaaaaa gatcgccgca ccattactgc
     4801 tttgttgcgt aagtttgcca ttcgtgaaga ccgcgaggag ctgggtaata acacgggacc
     4861 acgctttaag tctgagctga taaacccgcg caaaggtacg ccaacaagct acatcgcgaa
     4921 atacatcagt aagaacattg acgggcgtgg tctggctggc gagatcagca aggaaacggg
     4981 taaatccctg cgtgataacg ctgaatacgt taatgcctgg gcgtctctgc atcgtgttca
     5041 gcaattccgc ttctttggca ttccggggcg tcaggcttac cgtgaactgc gattgctggc
     5101 tggtcaggcg gcaaggcaac agggggacaa aaaagcaggt gcgccggtac tggataaccc
     5161 gcgccttgat gcaatcctgg ctgctgctga tgctggttgt tttgccacct acatcatgaa
     5221 gcagggcggc gtactggttc cccgcaaata tcacctcatc agaactgctt atgaaatcaa
     5281 cgaagaaccg accgcatatg gcgatcacgg tattcgtatt tatggcatct ggtcacccat
     5341 tgcagagggc aagatctgca ctcatgcggt gaagtggaaa atggttcgta aggccgttga
     5401 cgttcaggag gcggcagccg accagggcgc ttgcgcccct tggactcgtg gcaataactg
     5461 tccccttgct gaaaatttga accaacatga gaaagataaa tcagcagatg gggataccag
     5521 aacggacatt acctgcatgg atgacaagga attgcacgat tacctgcaca gtatgggcaa
     5581 aaaagagcac cgggaactgg cagcaagatt acgcctggtt aaaccgaaac ggcgtaaaga
     5641 ccacaaacag cgaattacag agcatcagcg tcagcagctc gtctatgaac tgaagtccag
     5701 aggatttgat ggcagcgaga aagaagtcga tttactgctt cgtggcggca gtattccgtc
     5761 aggagcaggc ctgcgtatct tctatcggaa ccagcgtttg caggaagatg ataagtggcg
     5821 ggatctgtat taattacgcg ggttaacaat tcgtgctctt aataatacca ggcatatcag
     5881 gctgatgaac gtaaaaaaac gttttacatc agtaagatt
//
LOCUS       DAJVKX010000196         5903 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.196, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000196 DAJVKX010000000
VERSION     DAJVKX010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.196"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            89..841
                     /gene="fnr"
                     /locus_tag="OPY25_004242"
     CDS             89..841
                     /gene="fnr"
                     /locus_tag="OPY25_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HCS0929700.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCKIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENSDALAALAGHTRNVA"
     gene            992..1939
                     /gene="uspE"
                     /locus_tag="OPY25_004243"
     CDS             992..1939
                     /gene="uspE"
                     /locus_tag="OPY25_004243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HCS0929701.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIREQAKYYLEAGVPIEIKVVWHNRPFEVIIQ
                     EVIAGSHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETLQLAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFSIDEKVTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGL
                     SAAFLGNTAEQVIDHLRCDLLVIKPDEYQTPVELDDEDD"
     gene            complement(1994..2248)
                     /locus_tag="OPY25_004244"
     CDS             complement(1994..2248)
                     /locus_tag="OPY25_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HCS0929702.1"
                     /translation="MIMMKLKSAKGKKFLLCLLAVFIVAASVVTRATIGGVIEQYHIP
                     LSEWTSSMYAIQSAMIFVYSLVFTILLAIPLGIYFLGGDE"
     gene            2487..3518
                     /locus_tag="OPY25_004245"
     CDS             2487..3518
                     /locus_tag="OPY25_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCS0929703.1"
                     /translation="MFTEFFLKNAFNLAILFSCGMALLVVRFWLSRNVQWKKGFTFHA
                     AQFFIYAIIIGTIGSILNNAIEDYNLRFISSGVIDFICTSLIALILTIKLFLIINQFE
                     KAQVNKGRDVTSTRILARVIKITIIVAIVLLYGEHFGMSLSGLLTFGGIGGIAVGMAG
                     KDVLSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITRINTFDHRPLYVPN
                     SVFSSISVENPGRMTNRRIKTVIGLRYEDADKIGLIVDAIRNMLQAHSDIDQKQTLLV
                     YFNEFADSSLNIMVYCFTKTTIWQEWLAVQQDVYLKIIAIVQENGADFAFPSQTLYID
                     DPEAAPAIK"
     gene            complement(3604..4206)
                     /locus_tag="OPY25_004246"
     CDS             complement(3604..4206)
                     /locus_tag="OPY25_004246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0929704.1"
                     /translation="MTKKVNLSTTAGADVSTINEAVSQRIKQFRSQKKMSLDELARRS
                     GVSKGMLVEIEGCKANPSIALLCKIAAAMGVSVADFVNVASEPMVHLINRDAIPVLWR
                     GEKGGSAKLMAGTSGPDMLELWQWIMHPGEQFESAGHPADTCELLFVNQGTLTLTVDG
                     RRFIIREGCSAVARTDMPHAYVNDTNEVLEFTMTVNEKSR"
     gene            4250..4936
                     /locus_tag="OPY25_004247"
     CDS             4250..4936
                     /locus_tag="OPY25_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HCS0929705.1"
                     /translation="MSSMLPSISPELARIAPGFRALSINVIAAPVRDAQVGEIALKEA
                     CQAVINGQPAWAQAHIDAWNAVFKAFGAKPKRTPCSAEALRKRVLKDGTMAALDPVVD
                     LYNAVSLRYAVPVGGENSAAYCGSPRLVFADGSETFDTLKEGKPVTESPEPGEVIWRD
                     DRGVTCRRWNWRQGVRTRLSASDKMMWFILESLPEMPVDELYAAENMLTDGLEKMMPG
                     LRFESTLIGV"
     gene            4964..5302
                     /locus_tag="OPY25_004248"
     CDS             4964..5302
                     /locus_tag="OPY25_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929706.1"
                     /translation="MSLFLTSFIFEKKEYDEEFYQLDGWIERYTQTIDGYIGMESYTD
                     AASGRMVNNYYWQTRESMELLINNLQHQQAKSQSHKWLSGYQTIIAEIQGCHNVNLPH
                     PLASFSVPYA"
     gene            complement(5408..>5903)
                     /locus_tag="OPY25_004249"
     CDS             complement(5408..>5903)
                     /locus_tag="OPY25_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCS0929707.1"
                     /translation="YISLGQEHAVTFGKTQLTLKPGILAEGEPLPCTKGLVSHNLLPG
                     YCIPGIKKRIIVVPSLDTPVCEWQVKEYSDRLKSAGSHSNRAVYVLSMDTPFAQARFI
                     REHDIHPGIIFVSDYACRQFLDNSGLKINELSIFARALIECDENNVVTHVSVPRDITH
                     LPVY"
BASE COUNT         1542 a         1426 c         1408 g         1527 t
ORIGIN      
        1 ttattccttc tccgggatag ctcagactta cgcgctcacc aaaaagatgt taaaattgac
       61 aaatatcaat tacggcttga gcagacctat gatcccggaa aagcgaatta tacggcgcat
      121 tcagtctggc ggttgtgcta tccattgcca ggattgcagt atcagccagc tttgcatccc
      181 gttcacactt aacgagcatg agcttgatca gcttgataat atcatcgagc gcaaaaagcc
      241 cattcagaaa gggcaaactc tgtttaaagc aggtgatgaa ctgaaatcgc tctatgctat
      301 ccgctccgga acgattaaga gctacaccat taccgagcaa ggcgatgagc agattactgg
      361 attccattta gcaggcgacc tggtgggttt tgacgccatt ggcagcggtc atcatccgag
      421 ctttgcacag gcgctggaaa cctcaatggt atgtaaaatc ccctttgaga cactggatga
      481 cctgtccggc aaaatgccta acctgcgtca gcaaatgatg cgtctgatga gcggtgaaat
      541 taaaggcgat caggatatga tcctgttatt gtcgaagaaa aacgccgaag aacgtctggc
      601 tgcgtttatt tacaacctgt cccgccgctt tgcgcagcgt ggtttttcac cgcgtgaatt
      661 ccgcctgacg atgacccgtg gcgatatcgg caactatctt ggcttaacgg tcgaaaccat
      721 tagccgtctg ctggggcgtt tccagaaaag cggtatgctg gcggtgaaag gtaagtatat
      781 tactattgaa aacagcgatg cgctggcggc cctcgccggt catacccgca acgtcgctta
      841 aacgtcagct aaaccattga tgttatcttc tgccatatcg ttaaattttt ctcatttatt
      901 gatctggcag aagcgcttcc cctgtttcat tcaccatatt tgagttactc tttagttaca
      961 aactgcgatg acagttgtaa ggagaccctg tatggctatg tatcaaaata tgctggtggt
     1021 catcgatccc aatcaggacg accaacccgc attacggcga gcagtttatt tgcatcaacg
     1081 gattggcggc aaaattaaag ctttcctgcc tatttacgat ttctcgtatg agatgaccac
     1141 cctgctttct cctgacgaac gcaccgcaat gcgtcagggc gtaataagtc aacgcacagc
     1201 ctggatacgt gagcaggcga aatattatct tgaagccggt gtccccattg aaataaaagt
     1261 ggtctggcac aatcgtccct ttgaggtcat catccaggag gttatcgccg gcagtcacga
     1321 tctggtgttg aaaatggcgc atcagcacga tcgactggaa gcggtcattt ttacccctac
     1381 cgactggcat ttgctgcgta aatgcccaag ccccgtgtgg atggtcaaag atcagccgtg
     1441 gccagagggc ggcaaagccc tggtcgccgt gaacctggca agcgaagagc cctatcacaa
     1501 tgctctcaac gaaaagctgg taaaagagac cttacaattg gcggagcagg ttaatcatac
     1561 cgaagtacac ctggtcggcg cctaccccgt tacgccaatc aatatcgcca ttgaactgcc
     1621 ggaatttgat cccagcgtgt ataacgacgc catcagaggc cagcatttac tggcgatgaa
     1681 agcgctgcgc cagaaattca gcatcgatga aaaagttacg catgtagaaa aaggcttgcc
     1741 ggaagaagtt atcccggatc ttgccgaaca tctccaggcg gggatcgttg tgcttggcac
     1801 cgttggacgt accggactct cggccgcgtt tttggggaac acggccgaac aggtcattga
     1861 ccatctgcgc tgcgacctgt tagtcattaa gcctgatgag tatcaaacac cggttgaact
     1921 ggacgacgag gacgattaat ccctcttccg tcctgccgga tggcgctgcc atccggccaa
     1981 cacctcattc ctgttactca tctccgccga ggaaatagat ccccaaagga atcgccagca
     2041 gaatagtgaa caccagactg taaacgaaaa tcattgccga ctgaatggca tacatagagc
     2101 ttgtccactc ggacagtgga atatgatatt gctcaatcac accgccgata gtcgcgcgcg
     2161 ttaccaccga tgccgcaacg ataaacactg ccagcaggca taacagaaat tttttcccct
     2221 tcgccgattt cagcttcatc atgatcatag tattgtcctt tacagatgac tttgttacct
     2281 gatagcaaca ataccatgac aatcacgcga tgtctgctcc ataaaacgta acattgtatt
     2341 tacataaaaa gtaaaccgct gagattaaag ctgatagcac tatttcttct ttttacttat
     2401 cgatgatcta cgcgtttatc ctgggtaaaa tacctgttaa tcaggtcatt ctgagctgtt
     2461 atcgtaggaa ggagcggaaa acaataatgt tcactgaatt ttttctcaaa aacgcattta
     2521 atctggcgat acttttcagt tgcggtatgg cgttgctggt cgtgagattt tggctcagcc
     2581 gtaacgtaca gtggaagaaa ggattcacgt tccatgcggc acagtttttt atttacgcga
     2641 ttattattgg aaccatcggg agcatcctga ataatgctat tgaagattat aatttgcgtt
     2701 ttatctcttc cggggtcatt gattttatct gcacctcgct cattgcgctt attctgacga
     2761 taaaactttt cctgattatt aaccaatttg aaaaagcaca ggtcaataaa ggtagagatg
     2821 tcaccagtac ccgtattctg gcacgggtca taaaaataac cattattgtc gcgattgtct
     2881 tactgtatgg cgaacatttt ggcatgagtc tgtccggtct gctgaccttt ggcggtatcg
     2941 gcggtatcgc tgttggtatg gcgggcaaag atgtcctgag caattttttc tccggtatta
     3001 tgctctattt cgatcgcccc ttcagtatcg gagactggat tcgttctcct gacagaaata
     3061 tcgaaggtac ggtcgccgaa atcggctggc gaattacacg aattaacaca ttcgaccacc
     3121 gcccgttgta cgtgcctaat tccgtctttt catccattag cgttgagaat ccgggacgga
     3181 tgaccaaccg tcgaataaaa acggttattg gattacgtta cgaagatgcc gacaaaattg
     3241 gcctcattgt tgacgctatc agaaacatgc tgcaggcgca cagcgatatc gatcagaaac
     3301 agacgctgtt ggtctatttt aatgaattcg ccgactcttc gctgaatatt atggtgtatt
     3361 gctttaccaa aacaacaata tggcaggaat ggcttgctgt acagcaggat gtttacctga
     3421 aaattattgc gattgtccag gaaaacggcg ctgacttcgc cttcccaagc cagacgctat
     3481 atatcgatga cccggaggcc gcgcctgcga taaaataaaa gatagccggt gcccgataac
     3541 gcttatcggg caccgaggct tccctgtccg gatgacgggt tgttagcgcc ttccttacgg
     3601 tgatcaacgg ctcttttcat tcaccgtcat ggtaaattca agcacctcat tagtgtcgtt
     3661 aacgtaggca tgaggcatat cggttctggc tacagcggag cagccctccc gaataataaa
     3721 gcgtctaccg tcgactgtta atgtcagtgt tccctgatta acaaacagta attcacaggt
     3781 gtctgccgga tgccctgccg actcaaactg ttcaccagga tgcattatcc attgccatag
     3841 ttccagcata tccggcccgc tggttcccgc cattagtttt gcactgccgc ctttctcgcc
     3901 gcgccacaac accggaatag catcccggtt gataagatga accatcggct cgctggcgac
     3961 gttgacaaaa tccgccacgg acactcccat tgccgccgcg atcttacata acagcgcaat
     4021 gcttggatta gctttacagc cttcaatttc caccagcatt cctttactga cgccggaacg
     4081 ccgcgcaagc tcatccagcg acatcttttt ttggctacga aattgtttga tacgttggga
     4141 aacagcttca tttattgtgc tgacgtcggc gcccgccgtg gtcgataagt tgactttttt
     4201 ggtcattggt cgatatcata gaataaaata gtcattacag gattatgcga tgtcttctat
     4261 gttaccgtca atcagcccgg aactggcccg tatcgctccc ggctttcgtg cattaagtat
     4321 taatgttatt gccgctccgg ttcgcgatgc gcaggtcgga gaaatcgcgt taaaagaggc
     4381 ctgtcaggcc gtaattaacg gacaaccggc gtgggcacag gcgcatatag acgcctggaa
     4441 tgcggtgttt aaagcattcg gcgcaaaacc aaagcgcacc ccctgctcgg ctgaagcgct
     4501 acgaaaacgc gtgttgaagg atggaacaat ggcggcgctg gacccggtcg ttgatcttta
     4561 taacgcggtg agcctgcgct atgccgtgcc ggtaggcggc gaaaatagcg cggcttattg
     4621 tggatcgccg cggctggttt tcgcagacgg tagtgaaaca tttgataccc tgaaagaagg
     4681 aaaacccgtt accgagtcgc cagaaccagg cgaagttatc tggcgcgatg acagaggcgt
     4741 cacctgtcgg cgctggaact ggcgtcaggg agtacgtacc cgactaagcg cttcagataa
     4801 aatgatgtgg tttatccttg aaagcttgcc ggaaatgccg gttgatgaat tgtacgcggc
     4861 agaaaacatg ctgactgacg gccttgaaaa aatgatgcca ggtttacgtt ttgaatccac
     4921 gttgataggt gtttgattga tattgcgtaa caggagaaat accatgtcgc tgtttctgac
     4981 aagttttatt ttcgaaaaaa aagagtacga cgaagagttt tatcaactgg atggctggat
     5041 tgagcgctat acacagacta ttgatggcta tattgggatg gaaagctata ccgatgccgc
     5101 cagcggaaga atggttaata attattactg gcagacccgc gaatcaatgg agctattgat
     5161 aaataattta cagcaccagc aggccaaatc acaaagtcat aagtggcttt ccggttacca
     5221 gacgattatt gcagaaattc aggggtgcca taacgttaac ctgccccatc cgctggcatc
     5281 attttcagtt ccctatgcgt gatgcaatag tatatgtatt aaatgtgggg gcacacagga
     5341 gaatgcctgc gcccctgcat tgccagttat tcggttttct gtgcaggggc ggcgctgata
     5401 taagtgatta atagacagga agatgagtga tatctcgtgg tacactaaca tgcgtaacca
     5461 cattgttttc atcgcactca atcaacgctc tggcaaaaat actgagctca ttaattttca
     5521 gcccggaatt atccaaaaac tggcggcaag cgtagtcaga aacaaaaatt atgccgggat
     5581 gaatatcatg ttcccgaata aaacgggcct gagcaaatgg cgtatccata ctcaacacat
     5641 atactgcccg gtttgagtgg ctacccgctg atttaaggcg gtcactatat tcttttacct
     5701 gccattcaca aaccggcgta tccagtgacg ggacgacaat aatccgcttt tttatccccg
     5761 ggatacagta acccggtaat aaattatggc tcaccagccc ctttgtgcag ggtaatggtt
     5821 cgccttcagc cagtataccg ggtttgaggg tcagttgcgt tttgccaaag gtcacagcgt
     5881 gttcctgacc caatgagata taa
//
LOCUS       DAJVKX010000197         5863 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.197, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000197 DAJVKX010000000
VERSION     DAJVKX010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5863
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.197"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            137..571
                     /gene="marR"
                     /locus_tag="OPY25_004250"
     CDS             137..571
                     /gene="marR"
                     /locus_tag="OPY25_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HCS0929708.1"
                     /translation="MKSTSDLFNEIIPLGRLIYMVNQKKDRLLNNYLSPLDITATQFK
                     VLCSIRCAGCITPVELKKVLSVDLGALTRMLDRLLCKGWIERLPNPNDKRGVLVKLTP
                     DGAAICEQCHQRPGQDLHQELTKNLTADEVATLEYLLKKILP"
     gene            591..974
                     /gene="marA"
                     /locus_tag="OPY25_004251"
     CDS             591..974
                     /gene="marA"
                     /locus_tag="OPY25_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HCS0929709.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRITNMHGESRYMLPLNHGNY"
     gene            1003..1218
                     /gene="marB"
                     /locus_tag="OPY25_004252"
     CDS             1003..1218
                     /gene="marB"
                     /locus_tag="OPY25_004252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HCS0929710.1"
                     /translation="MKMLFPALPGLLLIASGYGIAEQTLLPVAQNSRDVMLLPCVGDP
                     PNDLHPVSVNSDKSDELGVPYYNDQHL"
     gene            complement(1337..2239)
                     /gene="eamA"
                     /locus_tag="OPY25_004253"
     CDS             complement(1337..2239)
                     /gene="eamA"
                     /locus_tag="OPY25_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HCS0929711.1"
                     /translation="MMSRKDGFLALLVVVVWGLNFVVIKVGLHHMPPLLLAGLRFLLV
                     AFPAIFFVARPKVPLTLLLGYGLTISFGQFAFLFCAIKFGMPAGLASLVLQAQAFFTM
                     ALGAFVFSERLQRKQLAGIALAIIGVLVLIEASLNGQHIAMSGFMLTLAAAFSWACGN
                     IFNKKIMQHSPRPAVMSLVVWSALIPILPFLLSSLLLEGADHITQSLITIDMTTILSL
                     LYLAFVATILGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAAVLLGETLTGMQLAGA
                     VLIMAGLYINVFGFRVRRTARVRG"
     gene            2467..3654
                     /gene="ydeE"
                     /locus_tag="OPY25_004254"
     CDS             2467..3654
                     /gene="ydeE"
                     /locus_tag="OPY25_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HCS0929712.1"
                     /translation="MNPGLRRSTLALLASSLLLTIGRGATLPFMTIYLNRQYGLGVDL
                     IGYALTSALTIGVIFSLGFGILADKFDKKRYMLLAIIAFACGFIAIPMVHNVVLVVLL
                     FALINCAYSVFSTVLKAWFADNLTATTKTRIFSLNYTVLNIGWTVGPPLGTLLVMQSI
                     NLPFWLAAICSAFPLVFIQVWVTRSVAASEGKNAAIWSPSVLLRDKALLWFTLSAFLA
                     SFVGVAFASCISQYVMVVADSGFAEKVVAVVLPVNAVIVVSLQYAVGRRLTAVNIRPM
                     MTTGTVFFIAGLIGFIFSGDNLFFWGLSAAVFTIGEIIYAPGEYMLIDNIAPAGMKAS
                     YFSAQSLGWLGAAVNPLASGVILTTLPAWSLFVVLIIAIVFAWALMLKGMRITPTQQA
                     ITC"
     gene            3902..3997
                     /gene="mgtS"
                     /locus_tag="OPY25_004255"
     CDS             3902..3997
                     /gene="mgtS"
                     /locus_tag="OPY25_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HCS0929713.1"
                     /translation="MLGSINLFIVVLGIILFSGFLAAWFSHKWDD"
     gene            complement(4345..4718)
                     /locus_tag="OPY25_004256"
                     /pseudo
     CDS             complement(4345..4718)
                     /locus_tag="OPY25_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460475.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
     gene            5145..5672
                     /locus_tag="OPY25_004257"
     CDS             5145..5672
                     /locus_tag="OPY25_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-tetronate isomerase"
                     /protein_id="HCS0929714.1"
                     /translation="MRLEQHDIVTLDEAESVDSLTKKLGDLLVNQKLRLTSAESCPGG
                     KLASALCAAEDTPSFYGVGYVTFTDEAKAKILRVQRHSLAEHTAVSEAVVTEMAQGAK
                     DQAEVNISIAISGYGGPEGGEDGTPAGTVWFAWNINNTTFTSRQHFNGDCQEVLEKCV
                     RFALAELLFLLTKKA"
     gene            complement(5792..>5863)
                     /locus_tag="OPY25_004258"
     CDS             complement(5792..>5863)
                     /locus_tag="OPY25_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced acidophilic repeat
                     motif-containing protein"
                     /protein_id="HCS0929715.1"
                     /translation="QRASEAGKKGGQNSHSGGRKSGN"
BASE COUNT         1543 a         1467 c         1355 g         1498 t
ORIGIN      
        1 ttagttacaa gttatcacag cacaataccc cggacgcctt ttagcaaatc gtggcatcgg
       61 ccaattcatt tagttgactt atacttgcct gggcaatagt atctgacaaa attaattact
      121 tgccggggca accattttga aaagcaccag tgatctgttc aatgaaatca ttccgctggg
      181 tcgcttgatc tacatggtaa atcaaaaaaa agatcgcctg ttaaataact atttatcccc
      241 gctggatatc accgcaacac agtttaaagt gctgtgctcg atacgctgcg cgggatgtat
      301 taccccggtt gaacttaaaa aagtgctgtc tgtcgatctc ggcgcattga cgcggatgct
      361 cgaccgcctg ctgtgcaaag gctggatcga aagactgccg aatcctaatg acaaacgcgg
      421 cgtactggtg aagctaacgc cggacggcgc ggcaatttgt gagcaatgtc atcaacgacc
      481 agggcaagac ctgcatcagg aattaacaaa aaacttaacg gcggacgaag tggcaacgct
      541 tgagtatttg ctcaagaaaa ttctgccgta gacaaaaaag aggtatgacg atgtccagac
      601 gcaacactga cgctattact attcatagca ttttggactg gatcgaggat aacctggagt
      661 cgccgctctc actggaaaaa gtgtctgagc gttcaggata ttccaaatgg cacctgcaac
      721 ggatgtttaa aaaagagacc ggtcattcat taggtcaata catccgcagc cgtaagatga
      781 cggaaatcgc gcaaaaatta aaagagagca acgagcccat tctctatctg gcggaacgct
      841 atggctttga gtcacagcaa acattgaccc ggacgttcaa aaactatttt gatgtgccgc
      901 cacacaaata ccggatcacc aatatgcatg gcgaatcacg gtatatgctg ccgctgaacc
      961 atggcaacta ctagtttgtt tatgcgccac gcgaagagca ccatgaaaat gctgtttccc
     1021 gccctgccgg gtctgttact tatcgcctcc ggatatggca ttgcagaaca aactttgtta
     1081 cctgtggcgc aaaatagccg cgatgtgatg cttctgccct gtgtgggcga tccgccaaat
     1141 gaccttcacc ccgtgagcgt gaacagcgat aagtcagatg aattaggcgt gccctattat
     1201 aacgaccaac acctttaacc tctttgcccc gttttgcggg gcattttttt agtaccgtct
     1261 ggctatgaca agtccgccgc tattaccccg cggcatggtc tgaaattagc gtttgtcttc
     1321 ttagtaacat aatgcctcat cccctgacgc gcgcagtacg gcgcacacga aatccaaaca
     1381 cattgatata gagtccagcc ataatcagta ctgcgcccgc aagctgcatc ccggtcaacg
     1441 tttccccgag taacaccgcg gcgctcgcca gcccgactac cggcaccagc aatgataacg
     1501 gcgccacgcg ccaggtctca tagcgcccca gtaacgtgcc ccagatgccg tagccaagta
     1561 tagtggcgac aaaagccaga taaagcagcg acaatatcgt cgtcatatcg atggtaataa
     1621 ggctttgcgt aatgtgatcc gccccctcca gtagcagcga tgacagcagg aacggcagga
     1681 tcgggatcag cgcgctccag accaccagcg acatcaccgc cgggcgcgga ctatgttgca
     1741 taattttttt attaaagata ttgccgcagg cccagctaaa tgccgccgcc agtgtcagca
     1801 taaatcccga catcgctata tgctgtccgt tgagactggc ttcaatcaat accagtacac
     1861 ctataatcgc cagggcgatc cccgctaact gcttacgttg taaccgctca ctaaaaacaa
     1921 acgcccccaa tgccatggta aaaaaggcct gcgcctgtaa taccaacgac gccagtcctg
     1981 cgggcatacc aaactttatc gcgcaaaaga gaaaggcgaa ctgcccaaag cttatcgtca
     2041 gcccatagcc cagcaacagc gtaagcggga ctttaggccg ggcgacaaag aaaattgccg
     2101 gaaacgccac cagtaaaaac cttaatcctg ccagcaataa tggcggcata tggtgcaggc
     2161 ctactttgat gacaacaaaa ttgagccccc atacgacaac caccagtaac gccaaaaaac
     2221 cgtctttacg cgacatcatc ggcccctgtc attattaaaa ttttgtaaaa aggtaagtta
     2281 tcggaaatca gtgcgccata acaggacttt tctttttacc gtgagcatgg cattgaacaa
     2341 cacacgatgg gcaaaatcct gcgttatggt atgttaagac tacgctatag cgtacagaca
     2401 tcatgctttt gcgggcacgg tagattaaaa cgtcccgata cgtaacctcc atttcaggca
     2461 ggaaaaatga atccaggatt gagacgttcg acgttggctc tactcgcctc atcgctgtta
     2521 ttgacaattg gacgcggcgc cacgctcccc tttatgacca tctatcttaa ccgtcagtac
     2581 ggtttaggcg tggatctgat tggctacgcg ctgaccagcg cgttaacgat cggcgtcatc
     2641 tttagtcttg gctttgggat tctggcggac aagtttgata aaaagcgcta catgttactc
     2701 gcgattatcg ccttcgcctg cggatttatc gccatcccaa tggtgcataa tgtcgtactg
     2761 gttgtcctgc tttttgcgct tattaactgc gcctattcgg ttttttctac cgtcctgaag
     2821 gcctggttcg ccgataacct caccgcgaca acaaaaacac ggattttttc gctcaactat
     2881 accgtactca atatcggctg gacggttggc ccgccgctcg gcacgctgct ggtgatgcaa
     2941 agcatcaatt tacccttctg gcttgccgct atctgttccg catttccgct ggtctttatt
     3001 caggtatggg tgacacgttc ggttgccgcc agcgagggga aaaatgccgc tatctggtct
     3061 ccctccgttc tgctgcgcga caaagcatta ttgtggttta cgctttcggc atttctggcc
     3121 tcctttgtgg gggttgcctt tgcgtcctgt atttcacagt acgttatggt cgttgccgat
     3181 agcggcttcg cggaaaaagt ggtagccgtc gtcctgccgg ttaatgcggt tattgtggtc
     3241 agtttgcaat acgccgtggg ccgtcgactt accgccgtca atattcgacc aatgatgacg
     3301 accggcaccg tcttttttat cgccgggctc atcggattta ttttttcagg cgacaatctg
     3361 tttttttggg ggctttcagc ggcagtattc acgattggcg aaattattta tgcccccggc
     3421 gaatatatgt taattgacaa cattgcgcct gccgggatga aagccagcta tttttcagcg
     3481 caatcgctgg gctggctggg tgcggcggta aacccgctgg ccagcggcgt catcctgacg
     3541 acgcttcccg cctggtcgct tttcgttgtc ctgataatcg ccattgtgtt cgcctgggca
     3601 ctgatgttaa aaggaatgcg gattacccct acgcaacagg ctatcacctg ttaattatct
     3661 gcagccagtc atgtgcgctg tttctggcgc actgggttaa ccctatatat tgcaggctaa
     3721 ttatctgctg taactgcggt aattcaggaa tattcctggg cgctgacgaa aatattctaa
     3781 tgctttaccc ttccagtaaa ataaatacgc aattcagact ttgcttaagt ataaattagt
     3841 actatagtct gtacgaggtt ttttaaaaaa gaggatgcac gctaaaataa ggagaaacga
     3901 gatgttaggt agtattaacc tttttatcgt tgtattagga attattttat tttccggatt
     3961 tctggccgcc tggttcagtc acaaatggga tgattaatga acggagataa tccctcgcag
     4021 agccggcccc ttgctgcatc gttgcgcaag gggccgcttt tgtctggatg gcaggcaaaa
     4081 aaaaaccgcc ggttcaccag cggtaaatgc ttgcatggat agatttgtgt tttgcttata
     4141 cgctaccggg caaattcttg cgaggataac ggatcgctaa cgactgtagc accgtcaata
     4201 tcaatgaagc ttaaacgata cgcaaccaga cctgaataag acattatggg accttttgtc
     4261 cccagggcgc ttttacaaga cccatagtat caggccagcc gcatgccccg tatggctgac
     4321 ctggatattg ccggttagcg cgcgttattt ttgcaatcgg ttcacgcgga caagcggttc
     4381 cttcgctttc ttgtccagat ttgatccggc tgaacttccc gcccatcaaa tacggcggaa
     4441 ggaattatca cgttaatctc gccggactta tcacgaaata catagcgatc gtcgccttta
     4501 tgatcaataa ggttgccgcg cagcgaaacg gtcgcgccat catgcagggt ttttgcctgt
     4561 tcgatggtca ttttttctgc atcatccgta ccgcgataac catcctcaat agcatgaggc
     4621 ggcggcggtg ccacgtcttt ttttaatccc ccctgatctt ccgctagcgc gtaaggcatt
     4681 atcagaaaac ttaaaaatgc agccacctgt agtttcatgc tctctcctta ataacgtcta
     4741 tttgacgtat taagtctggc cgctattttt agtttttaca aacatgaatt tacccgcaga
     4801 atattaagca ataaaatcaa cccatccgga ttaatatgca accgatatca gcgccagtga
     4861 gcgcgaaagc gtaacggcgt aatagttaac ttgccacata gctgaagtca tatgcatcaa
     4921 cgtctggata gcaattcaga ataatcggct ttattttttg aggataatgg ccttccacat
     4981 aatcaatgac agtcatcgcc gtaagaaagt aagcaagtta tgcaacagcg ggtttgttgg
     5041 taactggata aaataatcat tcactgacaa tgtcataaaa taaatatgcc atacttgaga
     5101 agaacgaaca gatttcattt gtctctgtaa cggaaaaata aacgatgaga ttagaacagc
     5161 acgatattgt cacccttgat gaagccgaat ccgtcgatag cctgacaaaa aaacttggtg
     5221 atttactggt taaccagaaa ctccgtctga ccagtgcaga atcctgccct ggcgggaaac
     5281 tggcgtcagc attgtgcgca gcagaagata cgccctcatt ttacggtgtg gggtatgtca
     5341 cctttactga tgaagccaaa gcaaaaatct tacgcgtaca acgccacagt cttgccgaac
     5401 ataccgccgt cagcgaagcg gttgttactg aaatggcaca gggcgctaag gatcaggctg
     5461 aggtcaatat cagcatagcg atcagcggct atggcggtcc ggaaggcggc gaagatggca
     5521 cgccggcggg cacagtttgg tttgcctgga atattaacaa tacaactttt acaagccgac
     5581 aacatttcaa cggagattgt caggaagtat tggaaaaatg cgtacgcttc gccctcgctg
     5641 aattgctttt tctgttaacg aagaaagcat aaacaataat ttcatctgac cggtcagaat
     5701 aactcccggt cagaataaaa aaatgcgagc ctatggcccg catcgtatgt gcaatatttc
     5761 agaatatatt tatgaaatat cagcagtaaa attaattgcc ggatttccgt ccgccactgt
     5821 ggctattctg gccacctttt ttacccgctt cagatgcacg ttg
//
LOCUS       DAJVKX010000198         5843 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.198, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000198 DAJVKX010000000
VERSION     DAJVKX010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5843
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.198"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            632..1342
                     /gene="tcfA"
                     /locus_tag="OPY25_004259"
     CDS             632..1342
                     /gene="tcfA"
                     /locus_tag="OPY25_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001539136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone TcfA"
                     /protein_id="HCS0929716.1"
                     /translation="MNFKDTLPGVFLCVAMFACGHARANMLVYPMAAEINSSREEATS
                     LFVYSKSDHVQYIRTRIMRIEHPGMPQEKEVPAGNDIETGLVVSPEKFALSPGTKKTI
                     RVISTQAPEREEAWRVYFEAVPELEDDPQAGGKQNSSVSVNLVWGVLLRVSPSDPRPA
                     LVTDGHHLLNTGNTRLSLIRAGNCDTTCHWQNIGKSIYPGGSADIPAGIKSNAFRVEY
                     RTGANSPVISADLTAAGK"
     gene            1393..1968
                     /gene="tcfB"
                     /locus_tag="OPY25_004260"
     CDS             1393..1968
                     /gene="tcfB"
                     /locus_tag="OPY25_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein TcfB"
                     /protein_id="HCS0929717.1"
                     /translation="MYTECTYITVINNKARLFFMNMKTSFIAAAVALATVYSFSVSAV
                     QKDITVTANIDSTLELLQADGSSLPSTMKLDFMPGKGLVHKSLQTRLYSNDQTKSVNV
                     KLLNAPQLINVLDPTKTIDMEVTLGGRSLTTTNSVLEAKTLFPDGKTGDASALLNLDI
                     GQKAGAALQNLPAGEYSGLVSLVISQAVTAG"
     gene            2077..4763
                     /gene="tcfC"
                     /locus_tag="OPY25_004261"
                     /pseudo
     CDS             2077..4763
                     /gene="tcfC"
                     /locus_tag="OPY25_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein TcfC"
     gene            4786..>5843
                     /gene="tcfD"
                     /locus_tag="OPY25_004262"
     CDS             4786..>5843
                     /gene="tcfD"
                     /locus_tag="OPY25_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein TcfD"
                     /protein_id="HCS0929718.1"
                     /translation="MSNKMKWTSMTAHWSAIINFIRKYVYPARIIAILLMAGATLPQV
                     ADAITVDLNYDKNNVAVITPVWSQEWSVANVLGGWVCRSNRNENEGACEETHLVWWYA
                     FGAYSKIRLRFREQISHAEITLILLGSVRDACYTGVINMNAAACQWGRSLKLRIPSEE
                     LAKIPTSGTWKATLVLDYLQWGGDDPLGTSTTDITLNVTDHFAENAAIYFPQFGTATP
                     RVDLNLHRMNASQMSGRANLDMCLYDGGVKARSLQMKIEGSNKSGTGFQVIKSDSADT
                     IDYAVSMNYGGRSIPVTRGVEFSLDNVDKAATRPVVLPGQRQAVRCVPVPLTLTTQPF
                     NIREKRSGEYQGTLTVTML"
BASE COUNT         1467 a         1288 c         1557 g         1531 t
ORIGIN      
        1 tgtaaacatc aagcgtaacc atatgatgta tataagtttt tgtttgctga tatcatattt
       61 ttaacagata ttgagcaagt aaatctgatc taactgtaac tttagttttc taaattaatt
      121 actttgctta ctttttttta cctggttttg taaaacctca tgatgatcag tctatttgtg
      181 gctttgttta aggtttattt ggttttgtag tctgaattgt atctccctcc tggagggctt
      241 tctttagatt ctctgtctcc tacgttgtta tgttacgtat ttgttgcttt gaaggagggg
      301 gaaatacagt tccatttatc tgagtaagtc aggtacacag taacaacttt cttatgaaga
      361 atttccaaaa tttttactgc ggcgttatta attgttcagc gattcttaca gatctgtcgt
      421 tcgcttttgg tgaatgaaat ccgtggactt ttatttacta attttttctt tcctgaaaaa
      481 aacagaggta ttgagcgaaa aattttattc cgtatgatgc cctccacaca aaatgtatta
      541 acactgaatc gtaatttgct tctttatgct gataactttc tgtctatgct aatactaaaa
      601 tttagatgac ttttatacgg taaaatctgg tatgaatttt aaagatactc ttcccggggt
      661 gtttctctgt gtcgctatgt ttgcatgtgg tcatgccagg gcgaatatgc tcgtttatcc
      721 catggcggca gaaattaata gtagccgcga agaggccacc tcgctgttcg tctattctaa
      781 atcagatcat gtgcaatata ttcgaacaag aatcatgcgt attgaacacc ccggtatgcc
      841 acaggagaag gaggtaccag cagggaatga tatagagaca ggacttgttg tctccccgga
      901 gaaatttgct ctttccccgg gaacaaaaaa aacaatacgt gttatcagta ctcaggcacc
      961 ggaaagagag gaagcctggc gggtatactt cgaggctgtt cctgaactgg aagatgatcc
     1021 acaggcaggc ggaaagcaaa attcatccgt aagtgtgaat cttgtctggg gggtgttgct
     1081 gcgtgtttct ccgtcagacc ccaggcctgc gctggtaacg gacggtcacc acctgctgaa
     1141 tacgggaaac acacggcttt ctcttattcg ggctggcaac tgcgacacca catgccactg
     1201 gcagaatata ggcaaaagta tttatcccgg cgggagtgct gatattccgg ccggaataaa
     1261 aagtaatgca tttcgtgtgg aatatcgtac gggtgcaaat tcaccggtaa tctctgctga
     1321 tttaacagca gccggaaagt aaaaacacac ggagcgtacg ctatacccta catttattct
     1381 cagggggagc ggatgtatac cgagtgtaca tatatcactg taataaacaa caaagcaagg
     1441 ttatttttta tgaacatgaa aacatctttt attgccgcag ctgtggcatt ggccaccgtt
     1501 tattcttttt ctgtttctgc ggttcagaag gatattaccg tcactgccaa tattgacagt
     1561 acacttgaac tgctgcaggc cgatggttca tccctcccgt cgactatgaa gctggatttc
     1621 atgccgggta agggcctggt ccataaatca ctccagaccc gcctttacag caacgatcag
     1681 accaagtcgg ttaatgtaaa actgttgaat gctccacaac ttatcaacgt cctggatccc
     1741 accaaaacca ttgatatgga agtgactctg ggaggacggt cactgaccac caccaattct
     1801 gtactggaag ctaaaaccct gttcccggac ggaaaaactg gcgatgcttc agctctgctg
     1861 aacctggata ttggtcagaa ggctggagca gccttacaaa acctgcctgc cggtgaatac
     1921 agcggattgg tcagtctggt gatttcacag gctgtcactg ccggctaata actggttatt
     1981 agctcttcat ctgatccggt tttggggggg caccgttcgt acctgaaccg gatccggtat
     2041 tgatcttatt attcattgca attcaggtct ctttacgtga gtcgttattt ctggatgtat
     2101 tatttactgg gattgtgcag ttttaccagc caggcaactc ttattccccc tcctggattt
     2161 gaatctctgc tggaaggaca gactgagcaa attgaagtgt tgctaccagg gcattcactg
     2221 ggattatttc cggtggtggt taaaccggac accgtgcagt tcatgtcccc attgatggta
     2281 cttgaaagca gtgggcttgc cgcgttgccg gccgcagaac ggcaaaaagc gctggctgca
     2341 ctcagccgtc cgttgctacg taacagcaat ctggtctgtg gtgtctcaga agcaaaagac
     2401 agcagcgagt gtggttacgt ggcaacagat aaagaggatg ttgcggttat ttttgatgag
     2461 aacaacgctc agttatcttt gtttcttaac cgggactggt tgccggatga agaacgacgt
     2521 gataaacgct ggctgactcc gaccccggag ggtgtcagcg catttattca ccgccagacg
     2581 ctgtatctga gtgatgatct ccacagtcgt aatatgacac tgaatggtag cggtgccctg
     2641 gggcttggtg acggtcgtta tctgggaggc gactgggcgg ctatctggaa tcagtcagaa
     2701 cattacaata acagtcaggc ctggtttgac aatctgtttg tccgtcagga tctcggcaat
     2761 cagtattatc tccaggctgg tcggatggat cagcggaatc tgtccagcgc cacggggggg
     2821 attttgggtt cagtctgctt cccctgagcc ggtttgatgg attacgaacc gggaccaccc
     2881 aagcttatgt taaccatgag gtggaccata atgccactcc ggttatggtt caggttaccc
     2941 gaaatgcccg tattgatatt tatcgtggca gcgagttgct ggggagtcag ttcctgaccc
     3001 cgggaatgca taccctggat actcattctc ttccaccggg aagctatcct ctggcgttgc
     3061 gggtgtatga ggatgggatt ctgcggcgaa cggagaccca gcccttcagt aaggggggca
     3121 atagcttcag tgcacagacc cagtggttta ttcagggcgg gctggaagat accggggata
     3181 aagccagcca ttatgacggt gagactgtca tggctgccgg attccaaact gggctgcgga
     3241 aaaatatcag tctgaccgaa ggtatctctc tggcacatga ggcctggtac agtgaaaccc
     3301 gactgaattc acagcatgca gtgctggatg gcacgctgga cctttctgcc gggatactgc
     3361 atgggacaga cagcacgagc ggtaacactg agcaggtgac atacaacgac ggattttccg
     3421 cgagtctgtg gcgtaaccat acggaaagtg atgcctgtag tggtcgtcat ccacagtcag
     3481 tgcatgccag tatgacctgc cagacttcga tgaacgcctc cctgtcggtt tcggtgggga
     3541 actggtatgc cctactggga tacagtacca gcaggacaga aggtcggccg gtttaccggg
     3601 gatatgatga taacagtgac aaagaaaatg tgttctggcg acaggcatac atccctgcct
     3661 ctcaccgcga atctgctcag gctagtgcaa cgtacagcct taatatggct ggcatgaata
     3721 ttaataccca tgggggagta tggcgaaccc gaaatgacgg agtgaatgat gatggcttgt
     3781 ttatgagtgt cagtgtgtca tatgcctctc aaccaccgac aatgactggc agtaataggt
     3841 atacctcagc cgggaccgat attcacagta gccggaatca aaaaacacag acgtcctgga
     3901 atgtgaacca tgtgagatcc tggcagcagg atctgtatcg tgaactgtcg gtgggtttct
     3961 ccggttataa cgacgacagc tggagcggga gtctcggcgg acgcatgagc ggccgtatgg
     4021 gtgaactgag cgccactatc agtaactccc atcaacgtaa tgcgggcagc gccagttcac
     4081 tcaccgctgg ctacagctcg tctctggcgt tatcccgtaa tggactgttc tggggaggtg
     4141 gtcaggacgg tgaaccggcc tctggcatgg cggtgaacgt ggagtcagag ggggacgagg
     4201 gcagtagcgg gaaagtagtc agcgttcgtg gcagcagcca gccgttcagt ctcggttttg
     4261 gtcagcagtc gctgttgctg atggaaggct ataacgccac ggaggtgacc attgaggatg
     4321 caggggttag ttcacagggt atggcaggcg taaaagcggg agggggaagc aggtgttact
     4381 tcctgacacc cgggcatctg ctggttcaca acatcagcgc cagtatgagc cgactgtacg
     4441 ttggccgcgt actggacaag gatggcagac cgctgctgga cgcacagcca ctgaactatc
     4501 catttttgtc gttgggacct tccgggcgat ttagcctgca gagcgagcat aaagaatcca
     4561 gcctgtggct gctgtctaaa aacaggatcc tgcgttgtcc gatgtcagta cataaacgtc
     4621 gggatgttat gcaggtagtg ggtgatgtgc ggtgtgaatt aagtgacgtg gatgccctgc
     4681 cacaggcgtt gcaaatatcg ccgcgggtca tccgtttgct gaacgtggca ggtttgctgc
     4741 gccattccgt tcaggaagcc tgacgtagag ataaaggcgt taactatgag taataaaatg
     4801 aagtggacga gtatgacagc ccattggtca gcaattatta atttcatccg aaaatatgtt
     4861 tatccagcaa ggataattgc catcctgctg atggctggcg ctacactgcc acaagtcgcc
     4921 gatgcgatta ccgtcgacct gaattacgac aagaacaatg tagcggtcat cactcctgtc
     4981 tggtcccaag aatggagtgt agcaaatgtg ttggggggat gggtatgtcg ttcaaacagg
     5041 aatgaaaatg agggggcgtg tgaagaaaca catttggtat ggtggtatgc ttttggagct
     5101 tattcaaaaa ttcgtctgcg tttcagagaa caaatcagcc atgctgaaat cacgctcata
     5161 ctgctcggca gtgttcgtga tgcctgttat actggtgtca tcaacatgaa cgctgctgca
     5221 tgtcaatggg gtaggtcgct gaaacttagg ataccttcag aagagcttgc gaagatacct
     5281 acaagcggaa catggaaagc aacgttagtc ctggattatt tacaatgggg cggagacgat
     5341 cctttaggca catcaactac agatatcacg ctgaatgtaa cagaccactt tgctgaaaat
     5401 gcggctattt actttccgca atttggtaca gcaacgcccc gggtggacct gaatcttcac
     5461 cggatgaatg cctcacaaat gtcgggcagg gctaatctgg atatgtgtct gtatgacgga
     5521 ggtgtgaaag cccgttcatt acagatgaag atagaaggaa gcaataagtc aggtacggga
     5581 tttcaggtta taaagagcga ttctgctgat acgattgatt atgcggtcag tatgaattat
     5641 gggggacgaa gtattcctgt cacccgtggc gtggagttca gtctggataa cgtggataaa
     5701 gcagcaacgc gtccggtggt acttcccggg caacggcagg cggtacgttg tgtgccagtg
     5761 ccccttaccc tgacaacaca accctttaac atcagagaga agcgttctgg tgagtatcag
     5821 ggaacgctga cagtgacaat gct
//
LOCUS       DAJVKX010000199         5677 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.199, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000199 DAJVKX010000000
VERSION     DAJVKX010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5677
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.199"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..279
                     /locus_tag="OPY25_004263"
                     /pseudo
     CDS             1..279
                     /locus_tag="OPY25_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460897.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
     gene            493..1932
                     /locus_tag="OPY25_004264"
     CDS             493..1932
                     /locus_tag="OPY25_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCS0929719.1"
                     /translation="MMMQKKTWAVLLIPLCLTACHQTTNRSTAKDEILTGSYIDPTKK
                     RFPLADYSQSVDKWIPPDSADYTIPVIDSATQQRYFSALKSHYFGMDSEAHSPWNDFY
                     ITALLKKNAAQARDASIKQFLSDGSAYWGENFRLYTSRWKEEVRGNTDTQIDNIYHAS
                     RRGIMVRESLVRALPTDDPLFNDPRQAGEGYPFDNLQMSSLRPGTPVYTLTKSKDQRW
                     QYVVSPAVTGWVHSEDIASTDQKFITQWVLLAHKQLGAFINAPVSVHAAGVYYFTGRP
                     GTILPFRHQRAGQFLIAAPVRGSNGRAFIHWVWLSGNEFTAMPWKMTPENIAVLMKAM
                     HGAPYGWGNFNFYNDCSAEVRSLLMPFGIFLPRHSSAQVESAGRVVDLSHKNPQMRID
                     YLTRYGKAFTTLVYIPGHIMLYIGNTTMNGQVVPMTYQNIWGLRPNHANSRSIIGEAV
                     FLPLLRFYPENPELISLAGKVLFKLGYIE"
     gene            2145..2470
                     /locus_tag="OPY25_004265"
                     /pseudo
     CDS             2145..2470
                     /locus_tag="OPY25_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460895.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
     gene            2709..3374
                     /locus_tag="OPY25_004266"
     CDS             2709..3374
                     /locus_tag="OPY25_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecA family protein"
                     /protein_id="HCS0929720.1"
                     /translation="MKMEPLNENELEWLDDVLTKYNTDQVILDVAELDGLITAVLSSP
                     RPIEPEQWLVAIWGGPAYVPRWTSEKEMTRFMDLVFQHMADTAARLEDYPEQFEPLFG
                     LREVDGHELTIVEEWCFGYMRGVSLSDWSDLPDTLKPALEAIALHGTEENFALLDKMS
                     PEAFDKSVDAIRIAALELHAWWMAHPHTTPLQMPIKAEVKVGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(3449..4660)
                     /gene="tyrP"
                     /locus_tag="OPY25_004267"
     CDS             complement(3449..4660)
                     /gene="tyrP"
                     /locus_tag="OPY25_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HCS0929721.1"
                     /translation="MKNRTLGSIFIVAGTTIGAGMLAMPLAAAGVGFSVTLGLLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGSLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSINNWLGATLSPAAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVIM
                     LALLTPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMNGNIRRLRWVF
                     MTGSAIPLVAYIFWQLATLGSIDSPTFRGLLASHAGLNGLLQALREVVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRRSTVSGRLQTGLITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALLIPAMLVWQCRKQSPQAGYRVAGGTPALALVFICGIVVIGVQF
                     SIALGFLPDPG"
     gene            4887..5126
                     /locus_tag="OPY25_004268"
     CDS             4887..5126
                     /locus_tag="OPY25_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HCS0929722.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHTSLEAAIKARFGERARFHTCSA
                     SDMTAAELVAFLAAKGKFIAVEDGFSTHESKICRH"
     gene            complement(5172..5669)
                     /gene="ftnA"
                     /locus_tag="OPY25_004269"
     CDS             complement(5172..5669)
                     /gene="ftnA"
                     /locus_tag="OPY25_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HCS0929723.1"
                     /translation="MLKTEMIDKLNEQMNLELYSSLLYQQMSAWCSYHSFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGSLPRINSVSSPFAEYTSLDELFRATYEHEQLITQKIN
                     ELAHAAMTSQDYPTFNFLQWYVAEQHEEEKLFKSIIDKLTLAGKSGEGLYFIDKELST
                     LDTQN"
BASE COUNT         1493 a         1329 c         1468 g         1387 t
ORIGIN      
        1 aatataccga taatgcaaaa ttatttatta gcttcattaa tattgggatt gtaagttgcg
       61 ctttgctact tttttatttt gtatgagcct gagagtgcaa tcgtaaccta ctctcttccc
      121 ggtgagcttt cctcttcgac atgtgatgca cataatttta ttggctacgt cgatgcaaat
      181 gactttgcag agtatataaa aaaagtagaa ctgacgcgct acaatatgta ttgtctgaaa
      241 aaaacagggg caggccagtg gagtatttat gcaaattaaa cgagtatata actgttcagg
      301 ggtattttct gcacaattta attaaaggta gatagcgaac taatattcat cactaggtaa
      361 tgtgatccgc ttcatgcttt aatcacgttt tgcaatattg tcttaataac aggtcaacta
      421 cagataattt cgggttttcg tgaatggcgg ttttggtcag tctctatatt atgctttccc
      481 cgctttacgg agatgatgat gcaaaagaaa acctgggccg ttttattgat accattgtgc
      541 ctcaccgctt gccaccagac gaccaaccga tcaacagcca aagatgaaat tctcacaggg
      601 agctatattg acccgacaaa aaaacgcttt ccgttagcgg attattcaca gtcggttgat
      661 aaatggatac ctccggactc ggctgattac actattccgg ttattgatag tgctacccaa
      721 caacgctact ttagcgcact aaaatctcat tatttcggaa tggacagtga agcgcactcg
      781 ccgtggaatg atttttatat taccgcattg ctgaaaaaaa acgcagcaca ggcccgggat
      841 gccagtatta agcagtttct tagcgacggc agtgcttatt ggggggaaaa cttcagactt
      901 tatacctctc gctggaaaga ggaggttaga gggaatacgg atacgcagat tgacaatatc
      961 tatcatgcct cccggcgagg cattatggtc agagaaagtt tagtcagagc gctgccaacg
     1021 gacgacccgc tctttaacga tccccgtcag gcgggcgagg ggtacccgtt tgataattta
     1081 caaatgtctt cgctgcgtcc cggtacgccg gtctatacgc tgacgaagag caaagaccaa
     1141 cgctggcaat atgtcgtttc accagcggta actggctggg ttcacagtga agatattgcc
     1201 agtacggatc agaaatttat aacacagtgg gttttgctcg ctcacaagca actgggggca
     1261 tttatcaacg cgccggtttc tgtccatgcc gcaggcgtct attatttcac cgggcgaccg
     1321 ggtactattt taccgttccg acatcaacgg gcgggccagt tcctgattgc ggcgccagtt
     1381 cgcggcagca acggtcgcgc gtttatccat tgggtctggc taagcggtaa cgagtttacg
     1441 gctatgccgt ggaaaatgac gccggaaaat atcgccgtgc taatgaaagc aatgcacggc
     1501 gccccctacg gttggggaaa ttttaacttt tataatgatt gttcagccga agtccgcagc
     1561 ctgttaatgc cgtttggcat attcctgccc agacattcat ccgcgcaggt agagtctgct
     1621 ggacgggtgg tcgatcttag tcataaaaat ccccaaatgc ggatcgatta tctcaccaga
     1681 tacggaaaag cgtttactac gctggtctat attccagggc atattatgct gtatatcggt
     1741 aacacaacca tgaatgggca ggtcgtgccg atgacttatc agaatatctg gggattgcgc
     1801 ccaaaccatg ctaatagccg gagcattatc ggtgaggcgg tatttttgcc gttactgcgt
     1861 ttttatcctg aaaatcctga gctgatatcg ctggctggta aggttctgtt taagcttggt
     1921 tatatagaat aggttgacaa actgtgttat cgcggaagac atgattaagg caaccgtgcg
     1981 cgtggatata aagatagtat ccctgtaaac tgtgtctgaa aaaagtatac gctatagtgc
     2041 gggctgttta tttgaaatac tatctggagc tgattctgga tgtgattatg tgcctcacac
     2101 attgaagtga gagttattgt tggcggtatc tggctggagg ctgggtggta aaaagacgta
     2161 atttattgca ttttaataac ggtgcccggt cagagcgcga tcttggggat ctggtcacta
     2221 aagtttttga gaaagcggcg aaaaaagaac cgcaaccgct atacacattt agcctgccgt
     2281 tgctgagtgt gcaagatgag atccgtgttt actgtaagaa aaaaatatca aaatagggta
     2341 cgatacgctg tttatggaaa taaccttttc tgctgacaga gaagcggtag acgaactcat
     2401 taaacacttt tttactgaaa ataagctcta tttgagaggg cggttttatc tgtccgcggc
     2461 ggtggtataa gttagcatga gtataatata gcgagaaacc tatctctcac ttttgtgtgg
     2521 ggcgagcgct tcctggcgga aaatctgcgc cctgatcctc cttttgtgcg ttaacttccg
     2581 gaatcctcct catttcgtgt taatctggcc cctgatggtt gccatccaaa ctgcctgcaa
     2641 aaaaattatt tttatccgct gcaatgtaag aggcctacag gcggaagtca tcactgagga
     2701 aaagcattat gaaaatggaa ccattaaacg agaacgagct ggaatggctg gatgatgtgc
     2761 tgacgaaata caataccgat caggtcattt tggatgtcgc ggagctggac ggtctgatta
     2821 ctgcggtact aagttctccg cgtcccatcg agccggaaca gtggctggtc gcgatatggg
     2881 ggggacccgc gtacgtaccg cgctggacat ctgaaaaaga aatgacgcga tttatggatc
     2941 tggtattcca gcacatggcg gacacagccg cccggcttga agactatcca gaacagttcg
     3001 agccgctgtt tggcctgcga gaagttgatg gccatgaatt aacgattgtt gaagaatggt
     3061 gctttggtta catgcgcgga gtgtcgctgt ccgactggtc tgacttgccg gatacgctaa
     3121 aaccggcgct ggaagcgatt gccttacacg gcacggaaga aaactttgcg ctgttggata
     3181 aaatgagccc ggaagcgttc gataaaagcg ttgacgctat ccgtatcgcg gcgcttgagc
     3241 tgcatgcctg gtggatggcg catccgcaca cgacgccgct acagatgccg ataaaagcgg
     3301 aggtgaaagt ggggcgtaac gatccttgtc catgcgggag cggcaaaaaa tttaagcagt
     3361 gctgcctgca ttaatggctc gtaaacggcc atagcgtgat gattatcgag cctggacggc
     3421 gtccgggccc ggtaatcttt gcctggcgtt aacctggatc gggcaggaac cccagtgcga
     3481 tcgaaaactg gacgccaatc acgacaatgc cgcagataaa caccagcgcc agcgctggcg
     3541 tgccgcctgc cacacgatat cccgcctgag ggctctgttt acggcattgc cagaccagca
     3601 tggcagggat gagtagtgcc agcactgcca gcgctacgcc ggcatagcct aatgccatca
     3661 caaatccacg tgggtagaaa agcgcaaacg ccagcggcgg cagaaaggta atcagcccgg
     3721 tttgcaggcg tccggacacc gtactgcggc gctggaatag atcggccagg taatcaaata
     3781 atcctagcgc tacgcccaga aaagaggtcg ccagcgccag atcggcgaac aggtggaccg
     3841 ccagttcgac atgtggcgaa gcgaccactt ctctgagcgc ctgcagcagg ccatttaacc
     3901 cggcatggct ggccagtagc cctctgaatg tcggcgagtc gatacttccc agcgtggcga
     3961 gctgccaaaa aatataggcc actagcggaa tggcgctacc cgtcataaag acccaacgca
     4021 gccggcgaat gttgccgttc atataactca caatactcgg tacgcttccg tgaaaaccaa
     4081 acgaggtgaa aatgaccggt atggcggaca atgccagccc ctgctgtaaa ggaagcgtaa
     4141 gaagatttac tttatgaata tgtggcgtga gcaacgcaag catgatgacc agaaaaatga
     4201 tcttcgcgct aaacaggaag cggttaaaaa ggtcgaccag cgaggtgccc acacacacca
     4261 ccccaccggc aacaaaggtg aacagcagca ccccggcagc gggcgagagc gtggcgccaa
     4321 gccagttatt aatactggat gccagtaatt ctccggctcc ggaaatgtag gcggcggtga
     4381 gcgcatacat taagaacatc atgctgaatc ccgtaagcca ctgtccgtaa cgtccaagat
     4441 agcgttttgc caacgagccc agcccggtat ccgccggaac atgttgatat acttccagta
     4501 atagtagcgc ggtataacac atcagcgccc acagaccaat caacaatccc agcgtgacgc
     4561 tgaaaccaac gccagccgct gccagcggca ttgccagcat cccggcgccg atagtggtgc
     4621 ctgccacgat aaaaatactg cccagagttc tgtttttcac gctttctact accccggtaa
     4681 caaagaacgg tgatatccgc ggcgcagggt aaggcattac gctattttcg tcaaatggtc
     4741 gttacaatag gtgtactgga aattttacag ttccgggcat aaaagcgaat atgggaggag
     4801 acgcggacaa ccgccgcaaa cctgcgctag cgcaaagtcg ctcgcacaag gacacattag
     4861 gctacaagtt ttattcagga gggcttatgg attccattca cggtcacgaa gtactcaaca
     4921 tgatgattga gtctggcgag cagtacacgc atacctcgct ggaggcggca ataaaagcgc
     4981 gctttggcga gcgggcacga tttcacacct gttcagcatc agatatgacg gcggcggaac
     5041 tggtcgcgtt tctggcggcg aaaggaaagt ttattgcggt ggaggacggt ttttcaacgc
     5101 atgagagtaa aatctgccgc cattaatacg ccacggtgag agcgcgtctc accgtgtaag
     5161 gacgtgctgg attaattttg cgtatccagg gtggagagtt ctttatcaat gaaataaagc
     5221 ccttcgccgc tttttcccgc cagcgttaat ttatcaataa tagatttgaa cagtttttct
     5281 tcttcatgct gttccgccac ataccactgc aagaaattaa atgtcggata atcctggctg
     5341 gtcattgcgg catgagccag ttcattaatt ttttgcgtaa taagctgctc atgctcatag
     5401 gtcgcgcgga acagttcatc cagtgaggtg tactcagcga agggcgaaga aacgctatta
     5461 atgcgcggca ggcttccggt atcggtaagg tagtcaaaca ggcgctgcat atgcgtcatc
     5521 tcttcttgcg catggcgacg aagaaatgcg gccgcgcctt caaaactgtg atagctacac
     5581 cacgcgctca tttgttgata gagcagggag gagtacaact ccagattcat ttgctcattc
     5641 agtttgtcga tcatttctgt tttcagcatg gttccgc
//
LOCUS       DAJVKX010000200         5677 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.200, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000200 DAJVKX010000000
VERSION     DAJVKX010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5677
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.200"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(51..290)
                     /locus_tag="OPY25_004270"
     CDS             complement(51..290)
                     /locus_tag="OPY25_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929724.1"
                     /translation="MRLIIRAIVLFALVWIGLLMSGYGILVGSKVNAAGLGLQCHYLT
                     ARGTSTAQYLHTNSGIIGFSDCPIFRKIATVVDNG"
     gene            443..586
                     /gene="mgrB"
                     /locus_tag="OPY25_004271"
     CDS             443..586
                     /gene="mgrB"
                     /locus_tag="OPY25_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HCS0929725.1"
                     /translation="MKKFRWVVLGIVVVVCLLLWAQVFNIMCDQDVQFFSGICAINKF
                     IPW"
     gene            657..944
                     /locus_tag="OPY25_004272"
     CDS             657..944
                     /locus_tag="OPY25_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HCS0929726.1"
                     /translation="MNDVLNSGAFSLASLIVSMVVLVVGLALWFFVNRASSRANEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKEAEPATAASEPKEDEDIIRLVAER"
     gene            1536..1679
                     /locus_tag="OPY25_004273"
     CDS             1536..1679
                     /locus_tag="OPY25_004273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004157882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HCS0929727.1"
                     /translation="MINVICDNRLWVKRGTVLFMCGIFSKEVLSKHVDVEYRFSAEPY
                     IKQ"
     gene            1741..1950
                     /gene="cspE"
                     /locus_tag="OPY25_004274"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             1741..1950
                     /gene="cspE"
                     /locus_tag="OPY25_004274"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HCS0929728.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            2170..3915
                     /gene="ftsI"
                     /locus_tag="OPY25_004275"
     CDS             2170..3915
                     /gene="ftsI"
                     /locus_tag="OPY25_004275"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HCS0929729.1"
                     /translation="MKKKSDGDTRNFTPIRFALLCTAILLSMALLLGRVAWLQIVTPS
                     KLVKQEDMRSLREVTTASPRGMITDREGRPLAVSVPVNAVWADPKTIISKGGVGYNER
                     WQALASALHLSLSTLAERVNSNPAGRFIYLARQVSPQQAEWIDKLNLPGINLREESRR
                     FYPAGHVAANLIGFTNIDGQGIEGIEKSFNAQLTGKPGSRLVRKDKFGHVIENITEVN
                     PVPAHELQLSIDERLQTVTEDALDNAVIWNKAESGAAVLINIPTGEILSMASYPDFNP
                     NNREGAQLDDFRNRAISDTFEPGSTVKPLVIMTALQQGIVQPDSVIDTHPFTLDGHRI
                     RDVGYYPELTLTGILQKSSDTGVSHLSLAMPVQKLMDTYKSFGFGVPTGLGLTGESSG
                     LLPKRRYWSDLDRATFAFGYGLMVTPLQLAHVYATIGSFGIYRPLSITKVDPPVIGTR
                     VMPEELVHEVEHMMESVALPGGGGTKAAVRDYRIAVKTGTAKKIGDDGKYVDKYVAYT
                     AGVAPASNPRFALVVVINNPQNGAYYGGAVSAPVFSQIMGDVLRLENVEPDGMPADSD
                     HLLVMHGSHVAVPGS"
     gene            3981..4790
                     /gene="rlmA"
                     /locus_tag="OPY25_004276"
     CDS             3981..4790
                     /gene="rlmA"
                     /locus_tag="OPY25_004276"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HCS0929730.1"
                     /translation="MSFTCPLCHQPLTQINSSVICPQRHQFDVAKEGYINLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAVINLLRERLDQSATAILDIGCGEGYYTHA
                     FAEALPGVTTFGLDVAKTAIKAAAKRYSQVKFCVASSHRLPFADASMDAVIRIYAPCK
                     AQELARVVKPGGWVVTATPGPHHLMELKGLIYDEVRLHAPYTEQLDGFTLQQSTRLAY
                     HMQLTAEAAVALLQMTPFAWRARPDVWEQLAASAGLSCQTDFNLHLWQRNR"
     gene            complement(4787..5353)
                     /gene="mntP"
                     /locus_tag="OPY25_004277"
     CDS             complement(4787..5353)
                     /gene="mntP"
                     /locus_tag="OPY25_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HCS0929731.1"
                     /translation="MHFTATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGLGILASKFVLEWNHWIAFVLLIFLGGRMIIEGIRGGSDEDETPLRR
                     HSFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMIGRFIGP
                     MLGKRAEILGGVVLIGIGVQILWTHFHG"
BASE COUNT         1444 a         1328 c         1451 g         1454 t
ORIGIN      
        1 tataggggaa ttattggtga tagtttcact gtgaaattat ttattgccgc ttagccatta
       61 tccaccacgg tggcgatttt tctgaaaatg ggacagtcgg aaaagccgat aatgccgctg
      121 ttggtatgga gatattgcgc cgtgctggtg ccgcgtgcgg tcaggtaatg gcactgtaaa
      181 cccagccccg cagcgttcac tttacttccc accaggatgc catagccgct catcagcagg
      241 cctatccaca ccagggcaaa caatacaatt gcgcgaatga tcaaacgcat tactacctct
      301 tttttagtta gaataagagt agcgtgtaca ttgattgaaa caagtgaatc attcctaaaa
      361 acatataatg ccgctacagt tactcctggt ttaagtaact tatgataatt tagcgacata
      421 agatgtaaga tcggagagtg gagtgaaaaa atttcgatgg gtcgttctcg gcatcgtggt
      481 ggtagtatgc ctgttgctgt gggcgcaggt gtttaatatc atgtgcgatc aggatgtaca
      541 atttttcagc ggtatttgcg ccatcaataa atttattccc tggtaaacgt tttacaccag
      601 agatttcctt cccgtgtagc agtggtagaa tgacgtctct acattgaggt ggtgaaatga
      661 acgacgtttt aaactctggt gcgttttctc ttgcatcttt aatagtatca atggtggttc
      721 tggtggtggg gctggcgctc tggttctttg tcaaccgggc aagttcccgt gccaacgagc
      781 agatagaact gctcgaagcg ttgttggatc aacagaagcg gcaaaacgcg ttgttacgcc
      841 gcctttgcga agcaaacgaa ccagaaaaag aagcggaacc cgcaacagcg gcaagcgaac
      901 cgaaagagga tgaggacatc attcgtctgg ttgctgaacg ataatgctta ccggggcgca
      961 aatggcgcca gtgccatacg ccccatttcc ccgtcggatc tctccgcgtt gccgtttgca
     1021 actgatacta cagcatcaac accttaccta atatatggct ttatatgcaa catagtttta
     1081 tatgtataac aaatggacat atggcatttt tgtgataccg ctcattctct attaaaagcg
     1141 aaacgtttct ctctctttat ggattgtcat tgtttgttca ttattttaag gcattctgta
     1201 aagacgcaga acatcacaaa aagcggtgtc gaaaatcgct tttcttttct attattttga
     1261 ttaaaaggtg ttttttatca ttgtgacaat ttatgcataa ctcagcataa aaagtgatat
     1321 gaaaaataca gcttttaaat gtgatttgat gcactggaag aagcgaaatt attgagctat
     1381 ggtagaaaaa tggcttttca gcagtgacgt tgtcaggagt ccgtcagcgc gtgaggatat
     1441 atctttcgca attttgttgc ataaacgtgt tgtcaatttg tgaaggttct cgtaatttgt
     1501 gcgacggatc gagacacgtt taaaaatggc ttgccataat taacgttata tgtgataaca
     1561 ggctttgggt taaacgaggt acagttctgt ttatgtgtgg cattttcagt aaagaagtcc
     1621 tgagtaaaca cgttgacgtt gaataccgct tctctgccga accttatatc aagcagtaat
     1681 gtctcagttt tatctatgtt atgcctacgg gcaaagaaaa cactctaagg aattttgcaa
     1741 atggcaaaga ttaaaggtca agttaagtgg ttcaacgaat ccaaaggttt tggcttcatt
     1801 actccggctg acggcagcaa agatgtgttc gtacacttct ccgctatcca gggcaatggt
     1861 ttcaaaactc tggctgaagg ccagaacgtt gagttcgaaa ttcaggacgg ccagaaaggt
     1921 ccggctgctg ttaacgtaac agctatctga tcgacaccac tgatttgatg cgtttgtcgc
     1981 gtcagcctca gatataaagc ctcgctaaaa gcggggcttt ttaattcaat atccttcaaa
     2041 atgtgtctgg atgcgctctc gttagcgatt tgttgcaaag gcgcgatgtt attagcattg
     2101 ttttttctgg tttttccggc cgtttcccgt taaatcaatc acctgaaaaa tgattcggct
     2161 ggagatcagg tgaaaaagaa aagcgacggc gatacccgta attttacacc catacgtttt
     2221 gcactacttt gcactgccat tctgctcagt atggcattgt tgttagggcg ggtggcatgg
     2281 ctgcaaattg ttacgccgtc gaaactggtg aaacaagaag atatgcgctc gcttcgtgaa
     2341 gtgaccacgg cctctccacg cggcatgatc accgacagag aagggcggcc cttagcggtg
     2401 agcgttccgg ttaatgctgt ctgggccgat ccgaaaacta tcataagcaa aggcggcgtt
     2461 ggctacaatg agcgctggca ggcgctggcc agcgccttac atctgtctct cagtacgctt
     2521 gcggaacggg taaacagtaa cccggcaggt cgttttatct acctcgcgcg ccaggtttca
     2581 ccccagcaag ccgaatggat agataaactg aatctaccgg gtattaacct gcgggaagag
     2641 tcgcgccgtt tttaccctgc cggacatgta gcggccaatt tgatcggctt taccaatatc
     2701 gacgggcagg gaatagaagg tattgaaaag agctttaacg cgcaactgac gggaaaaccg
     2761 ggctcccggc tggtgcgtaa agataaattt ggtcacgtta ttgagaacat tacggaagtg
     2821 aatccggttc ctgctcatga acttcagctt agcattgatg aacgtctgca aacggttacc
     2881 gaagatgcgc tggataacgc cgtcatctgg aacaaagcgg aatccggcgc tgccgtattg
     2941 attaacatcc caacgggtga aattctctcg atggcgagct acccggattt caacccgaac
     3001 aaccgtgaag gcgcgcagtt ggacgatttt cgtaaccgcg cgattagcga cactttcgaa
     3061 cccggttcta ctgtgaagcc attggtcatt atgactgcgt tacagcaggg tatcgtgcaa
     3121 ccggacagcg ttatcgatac ccatcctttt actctcgatg gacaccgtat ccgcgacgtc
     3181 ggctactatc cggaactgac attaaccggc attttgcaaa aatccagcga taccggcgtt
     3241 tctcaccttt ctctggcgat gccggtgcag aaattaatgg atacttataa aagctttggt
     3301 ttcggcgtgc ctaccggact gggtctcacc ggagagagca gcgggttatt accgaaacgc
     3361 cgttactgga gtgatttaga tcgcgctacc ttcgcttttg gctatggatt aatggtgacg
     3421 ccgctgcaac tggcgcatgt ttatgccacg attggcagct ttggtatcta ccgtccgtta
     3481 tcgatcacca aagttgatcc gcccgtgatc ggcacgcgag taatgccgga agaactggtg
     3541 cacgaggtgg aacatatgat ggagagcgtc gcgttgcctg gcggcggcgg aacaaaagcc
     3601 gcagtaagag actaccgtat tgcggtcaaa accgggacgg cgaaaaaaat tggcgatgat
     3661 ggtaaatacg ttgataagta tgtggcatat accgcaggcg tcgcgccggc aagtaacccc
     3721 agatttgcgc tggtggtggt gattaataat ccacaaaatg gggcttatta tggcggtgcg
     3781 gtatctgcgc ccgtattcag ccagatcatg ggcgatgtac tgcggctgga aaatgttgag
     3841 ccagacggta tgccagccga ttcagatcac cttctggtga tgcatggcag ccacgttgcg
     3901 gttccgggct cgtaaaggat tttcccgggg cgcaattcgc gttacacttg cgccctttag
     3961 cgccccagtc cggagttgtc atgtcgttta cctgtccgct ttgccatcaa ccgcttacgc
     4021 agattaatag cagcgttata tgtccacagc gccatcagtt tgatgtggcg aaagagggct
     4081 acatcaatct gctgccggta cagcataaac gttcgcgcga tccgggcgac agcgccgaaa
     4141 tgatgcaggc gaggagagcg tttcttgatg caggccatta tcagccgctg cgcgatgcgg
     4201 tgattaacct gttgcgcgag cggctggatc agtcggccac ggcgattctg gatattggct
     4261 gcggcgaggg gtattacact catgcttttg ccgaggcgtt gccgggagtt accacgtttg
     4321 gactggacgt tgctaaaacg gcgatcaaag cggcggcgaa gcgctattcg caggtgaagt
     4381 tttgtgtggc gtcaagccat cgactgccct ttgccgatgc gtcaatggat gcggtgatca
     4441 gaatctacgc tccgtgtaag gcgcaggaat tggcgcgtgt ggtgaaacct ggtggttggg
     4501 tcgttaccgc cacgccgggg ccgcatcatc tgatggaact aaaagggctc atttatgatg
     4561 aggtgcgttt acatgcgccg tataccgagc agctcgacgg attcacattg cagcagagta
     4621 cccgccttgc ttatcacatg cagctcaccg ccgaagcggc tgtagcactg ttgcaaatga
     4681 cgccatttgc ctggcgcgcc agaccagacg tgtgggaaca actggctgcc agcgccggac
     4741 ttagctgcca gacggatttc aaccttcatc tctggcagcg taaccgttaa ccgtgaaaat
     4801 gcgtccagag gatctggacg ccaattccta tcagtacgac cccgccgaga atttcagcac
     4861 gcttacccag cattgggccg ataaagcgac cgatcatcat tccgagggtg gacatgataa
     4921 gcgtggcgca accgatagct aatgcggttg cgatgatgtt tacctgcaaa aacgccagac
     4981 cgacgccaac cgccatcgca tcgaggctgg tcgcgatagc cgtcgtgact aatagccaaa
     5041 agctgtgacg acgtaacggt gtttcatctt catcactacc gccgcggata ccttcgatga
     5101 tcatgcgtcc gcccagaaag atcagcagaa caaaggctat ccagtggttc cattccagaa
     5161 cgaatttact cgccaatatc cccagccccc agccgatcaa cggggttagc gtttcaaccg
     5221 cgccaaagat aagaccggta cgcaacgctt ctgagaattt gggtttatgt agggtggcgc
     5281 ctttgccaat tgatgccgcg aaagcatcca tcgacatgcc gaaagcgaga agaacagtag
     5341 cagtaaagtg catgacagcg tcctgaccgg ggtatccatt aaacacatca ctgcccccag
     5401 caaacatgca tgtcgccatt ctgtgacgaa atacacagca gttgatgcgc ctatggtctc
     5461 gcctgaccag cggcggctgg tccgtacgcg ccacgttttg caacgagtat gttgacacgt
     5521 acatttccgg agtctggaaa tcggctactc cctaattgac ggcgcaacat taacatattt
     5581 ttagaatata aaacaacagc gataaaatat tatttgcctt ctaattgaaa acgattttca
     5641 tttagattta ttcatcaata aaacgttaaa ttaaata
//
LOCUS       DAJVKX010000201         5674 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.201, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000201 DAJVKX010000000
VERSION     DAJVKX010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5674
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.201"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            144..980
                     /locus_tag="OPY25_004278"
     CDS             144..980
                     /locus_tag="OPY25_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1311 domain-containing protein"
                     /protein_id="HCS0929732.1"
                     /translation="MFRKAVTLLFLLSPAVSYAGLFDSTPELKCGNDNAVTAAKEWIY
                     NEALGRLQQDYIKEPSTLFFDIPQTQYEQQLRAIPVQFSDVITQNPQPENANLRTCSA
                     TVAMSIPQPLFKLMKDLPNTLFYISQGDGQVINNTVTWKQVNYNIQLADNNKDIVVTP
                     VQKTDKLARSIYVMARMTVSGDSIIKKKNNSLIEIAAKKFESRDRELNQVWNSLPTSA
                     RTALKQEQRVWVTKKEQQCGKLSDAKSEDIPAEKRISIYKCQLEMTIARTTYLDGSEL
                     PD"
     gene            1057..1851
                     /locus_tag="OPY25_004279"
     CDS             1057..1851
                     /locus_tag="OPY25_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HCS0929733.1"
                     /translation="MELLNQLKRLCRALRGTPNSWPAIDLSLPGGRHLHLVGSIHMGT
                     RDIAPLPAKLVKKLRQADALVVEADISGNETPFSNLPKCPPLVERLSAGLLNTLEKRV
                     SELGMPLIHFDNQPLWQIAMVLQATQAQRLGLRPDYGIDYQLLQAAREMSLPVQELEG
                     AKHQLELLCDLPDGGMALLDDTLTHWHTNARLLQVMIGWWLEQPPTSIGASLPRTFSQ
                     PLYDVLMVKRNEAWRDALLALPPGRYVVAVGALHLYGEGNLPQILK"
     gene            2052..2531
                     /gene="ybaK"
                     /locus_tag="OPY25_004280"
     CDS             2052..2531
                     /gene="ybaK"
                     /locus_tag="OPY25_004280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HCS0929734.1"
                     /translation="MTPAVKLLEKNKIPFNIHTYDHDPNETNFGDEVVRKLGLNADQV
                     YKTLLVAVNGDMKQLAVAVTPVAGQLDLKKVAKALGAKKVDMADPMVAQRTTGYLVGG
                     ISPLGQKKRLPTLIDAPARTFATIYVSGGKRGLDIELAADDLAAILSAKFADIARRD"
     gene            complement(2648..4299)
                     /locus_tag="OPY25_004281"
                     /pseudo
     CDS             complement(2648..4299)
                     /locus_tag="OPY25_004281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459489.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
     gene            4472..>5674
                     /locus_tag="OPY25_004282"
     CDS             4472..>5674
                     /locus_tag="OPY25_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929735.1"
                     /translation="MAMSEPTQPLAGAPAAAAKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQAEFSLTFVQIGLITLTFQLASSLLQPVVGYWTDKYPMPWSLPVGMCFTLS
                     GLVLLAMAGSFGGVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLATLLAIVVLAQISRWYAAQHRIAKGKPKAIIAN
                     PLPRNKVVLAVSVLLLLIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLVLPYATLYWTGILTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIYLVYKICAFLPLL
                     GILTIFLPD"
BASE COUNT         1348 a         1500 c         1385 g         1441 t
ORIGIN      
        1 atcaggcagc atcagctgcc tgatatatta ttaagccatc agcaatttac cgtatcaata
       61 tataaaaatt taaccgcaca tcctatagaa aaataaaaac aacattttat aatgtttttt
      121 tgaatcataa ggatgtgtta tttatgttta gaaaagcagt tacgcttctt ttcctgcttt
      181 ctcccgcagt tagttatgca ggattatttg attccactcc agagttaaaa tgtggcaacg
      241 ataatgcagt cacggcggca aaagagtgga tttacaatga agcattaggt cgtttacagc
      301 aagactatat taaagagccc tccacgcttt tcttcgatat cccccagact caatacgagc
      361 agcaactccg ggctattcct gttcaattca gtgatgtaat cacgcagaac cctcaaccag
      421 aaaatgccaa cctacgaact tgctcggcta ccgtcgccat gagtattcct cagccattgt
      481 ttaaattaat gaaagactta ccaaatactc tattctatat ttcacaaggg gatggacagg
      541 taataaacaa tacggtgacc tggaaacagg ttaactacaa tattcagcta gcagacaaca
      601 ataaagatat tgttgtcacc cctgtgcaga aaaccgataa attggcgcgg tctatttatg
      661 taatggcaag aatgacggta tctggtgata gcattataaa gaaaaaaaat aactcactga
      721 ttgaaatcgc agcaaagaaa tttgagagta gagatcgcga gcttaatcag gtctggaatt
      781 cgctacccac ctctgcccga acggcattaa aacaagagca gcgagtctgg gtgacaaaaa
      841 aagagcaaca gtgcggcaaa cttagcgatg caaaatccga ggacatacct gctgaaaagc
      901 gcatcagtat ttataaatgc cagcttgaaa tgaccatcgc cagaacgacc tatctcgacg
      961 gcagcgaact acccgactga tcgttgacgt cccgtcaggg cgcattgcgc ccttttctcc
     1021 aacgcgctag catgagcttt ttcaaaggga gcgcgtatgg agctattaaa tcaacttaaa
     1081 cgtttatgcc gcgcgctgcg tggtacccca aatagttggc ctgctatcga tctctccctg
     1141 cccggcggtc gtcatctgca tctggttggc agtattcata tggggacgcg cgatatagct
     1201 cctcttccag caaagctggt gaaaaagcta cgccaggccg acgcgctggt cgttgaagcg
     1261 gatatttccg gtaacgaaac gccattcagc aatctcccca aatgcccgcc gttggtcgaa
     1321 cgtctcagcg ccgggctgct aaacacactg gaaaaacggg tcagcgagtt gggtatgccg
     1381 ctgatccatt ttgataatca acctttatgg cagatagcta tggtgctaca ggccacgcag
     1441 gcgcaacggc tgggattgcg cccggactat ggcattgatt atcagctatt acaggctgcc
     1501 cgcgaaatgt cgctgccggt gcaagagctg gaaggggcga aacaccagct cgaactacta
     1561 tgcgatctgc ccgatggcgg gatggcgctg ctcgacgaca cgctgacgca ctggcacacc
     1621 aacgcacggc ttttgcaggt gatgatcggc tggtggcttg aacagccgcc gaccagcatc
     1681 ggcgcttcgc tccccagaac gtttagccaa ccgctgtatg atgtactgat ggtgaaacgc
     1741 aatgaagcct ggcgcgacgc gctgctggca ctgccaccgg gacgctacgt ggtagccgta
     1801 ggggcgctac atctgtacgg cgaaggcaac ctaccgcaaa tattgaaata aaaaatggcc
     1861 aatatcgcta ttggcccgtc aaagaggaat ttcatcgtta ttattatccc gacgctttcg
     1921 cttcggatct tcagattgtc gctcaaagtt gccgcaactg ccaagaccta atgcacaaga
     1981 ttatactatt ttttagtccg ctttcgggcg tatgctgatg gcaaatcacg tctgtagtaa
     2041 gaaggaacgt tatgacaccc gcagttaagt tactcgaaaa gaacaagatt ccgtttaaca
     2101 ttcacaccta cgatcacgat ccgaatgaaa ctaactttgg cgatgaagtg gtgcgtaagc
     2161 tcgggctaaa cgccgatcag gtgtataaaa cgcttttggt tgccgtgaat ggcgatatga
     2221 agcaactggc cgtcgccgtg acgcctgtag ccgggcagct ggatttgaaa aaagtcgcca
     2281 aagctctggg cgcgaaaaag gtcgatatgg ccgacccgat ggtggcgcaa cgcaccacgg
     2341 gatacctggt cggcgggatc agtccgctgg gacagaagaa acggctgcct acgctgattg
     2401 acgcgccagc ccgcacgttt gccactattt atgtttccgg tggtaaacgc gggctggata
     2461 ttgaactggc ggctgacgat ttggccgcca tcctgagtgc taaattcgct gatatcgcgc
     2521 gtcgggatta agcctgcgta aaatacattg ccggatagcg gcgcaaacgc cttatccggc
     2581 ctacagcata cataatccgt aggccttaag gctgtgcgcc atcaggcaga gatggctatc
     2641 agtaccgcta cagccagttc acctcgccat ttggcgtaaa cgccgccgca tccaacggtg
     2701 aattctgctg aataaactct ttcagcactt ccgcgtcaat aaacccggta ttcacgtagc
     2761 ccggtttgtt atcgatgcgc ggataaccat cgccgcccgt ggcgttgaaa ctcagcgtcg
     2821 ccatgcggta ggttttggcc ggatcaacag gctcgccttt gattttcaga tcggtgagct
     2881 tgccctcttt ggcgacaaag ctcacattgg cgaactgtgg ataggcgccg gagtccggtt
     2941 tcatctgcgc tacggcggtg agataatcaa ccacctcttt gccgctcata tcggcataca
     3001 ccacaatgtt gccgaacggc tgtaccttga gcacgctttt ataggtaata tctcccgcct
     3061 caatcgagtc gcgaataccg ccgccgctca tcacgccaaa atcggcaccg gtgcgcgcga
     3121 tctgcgcagc cagaatcacc cgtcccatat tggtctggac aaatctgacc ttactgcgat
     3181 cgccttcaag caggccattc acgctaccaa ttttcacctc cagttgcgct ttacctttat
     3241 tctggaacgg cgttaataac gagagcattt gcggattttc ggcgatttcc ggcgtgtaaa
     3301 gtacacgctc gcttttcccg ttatcccagg tcactttttt cttgagattt accggaataa
     3361 gctggtagtt aaccattttc atctcgccgt tacggaattc gaaatccgcg tggcccacat
     3421 atttacccca ctcatgcgcc tgcacgctcc agatgccatt ttgcttatcc ggcgcgcagg
     3481 gcgttcccgt tacgtaattc acctgttttt attttccgac gccatgcata ccgggtcttg
     3541 tgagtgaccg cccacaatca tcgccagcga accggcaggc agactacgcg ccatctcaac
     3601 gtcgcccggc gcattcgaac cgtgatcgcc gttgtcataa tgtcccatat gcgtggtcgc
     3661 gataatcacg tccggttttt cattcatatt aagttcctga atcaccacct ttgcttcttc
     3721 agcaggttta cgaaactcaa tatcggtgaa atattccggg ttgcctattt tcgccgtgtc
     3781 atcggtggtt aagccgatta ccgcgatttt tatatcctgg cgtgtaaaaa tagcccacgg
     3841 cttaaacaga cgctcgccgg tacttttttg ataaatattg gcggaaagaa agggaaactt
     3901 cgcccacttt tcctgctggc gcaatacggt gagcggatta tcaaattcat gattaccgac
     3961 ggccatagcg tcgtagccaa tcagattcat cccgcggaaa tcgggctccg catcctggag
     4021 atcggattcc ggcactccgg tattaatgtc gccgccggat aacaacagga cgcttccccc
     4081 ctcttgcgcc acctctttac ggatactgtc caccagcgtt ttttgcgccg ccagaccata
     4141 ttcgccatat tcgctgcgcc agaagtgacc gtggtgatcg ttggtatgca ggatagtaat
     4201 tttataggtt ttatcttttt cgtaagcctg tgcaggctga gtcgtcagcg cgaacgccgc
     4261 cagtaacgcc agcgccacac cccgtttcaa aaatttcatc tttctctccc tgactcaata
     4321 tcaaccgcag aaattacctt tccttgcaat aatagacaaa tatgttttca gaattgagac
     4381 ttccttcaaa cacatttcac aggtatgtta ggcaagtaat aattacacat cctactatct
     4441 ccaacatcgc ataaaattta agtgactttc tatggccatg agtgaaccaa cccagccgtt
     4501 agccggcgcg cccgcagcgg ccgctaaagc acgtacttcg tttggtattt tgggcgcgat
     4561 cagtctttcc catctgctga acgatatgat ccagtcgcta atcttagcta tttatcccct
     4621 gttgcaggcg gagttttcgc tgactttcgt ccagataggt ttgatcaccc tgacgttcca
     4681 gctcgcctca tcgctactgc aaccggtcgt cggctactgg acggataaat atcccatgcc
     4741 gtggtcgctg cctgtcggca tgtgttttac cctgagcggg ctggtactgc tggcaatggc
     4801 gggaagtttt ggcggcgtat tgctcgctgc ggcgctggtg ggtaccggct cgtccgtttt
     4861 tcacccggaa tcgtcccgcg tggcgcgcat ggcctccggc ggacgtcatg gtctggcgca
     4921 gtctatcttc caggtcggcg gtaacttcgg cagttcattg ggcccgctgc tggccgccgt
     4981 gattatcgcg ccctatggca aagggaatgt cgcctggttt gtgctggcca cgctgctggc
     5041 gatcgtggtg ctggcgcaga tcagccgctg gtatgcagcc cagcaccgga tagcgaaagg
     5101 caagccaaaa gcgataatcg ctaacccgct gccgcgcaat aaagtcgtgc tggcggtcag
     5161 cgtgttattg ctactcattt tctcgaaata tttctatatg gcgagcatca gtagctacta
     5221 caccttttat ctgatgcaaa aattcggatt atcaatacaa aacgcgcagc tccatctgtt
     5281 tgccttcctg tttgcggtgg ctgccgggac ggttatcggc gggccggtgg gcgataaaat
     5341 cggcagaaaa tatgtgattt ggggctctat tctcggcgtc gcgccgttta cccttgtttt
     5401 accctacgcc acgctgtact ggacggggat tttaacggtg attatcggct ttattctcgc
     5461 gtcggcgttt tccgccattc tggtgtatgc ccaagagctg ctgccaggac gcatcggcat
     5521 ggtttccggc ctgtttttcg ggtttgcctt cgggatggga ggcctgggcg cagcggtgct
     5581 ggggctgatt gcagaccata ccagtatcta tttagtttat aaaatctgtg cttttctgcc
     5641 gcttctgggg atactgacca tattcttacc tgat
//
LOCUS       DAJVKX010000202         5585 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.202, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000202 DAJVKX010000000
VERSION     DAJVKX010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5585
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.202"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            572..1243
                     /locus_tag="OPY25_004283"
     CDS             572..1243
                     /locus_tag="OPY25_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiH family protein"
                     /protein_id="HCS0929736.1"
                     /translation="MAQQVDGAAMPLDTEKVGIKGYLAFFLTIIFFSGVFSGSEGWWR
                     VFDFTVLNGSFGHVTGTQTFRGAGGTGAKDGFLFALELAPSVILSLGIIAITDGLGGL
                     RAAQQLMTPILKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKVIFAA
                     WQTSGSAIITNYFSSGVAVFAFLGTSVIIPLVVILLFKFIGANLLRIWINIEERRHPA
                     QGAQS"
     gene            1240..1701
                     /locus_tag="OPY25_004284"
     CDS             1240..1701
                     /locus_tag="OPY25_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HCS0929737.1"
                     /translation="MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICQPVMALWGLPGEAATVLLASLMSMGGAVGVAASLATAGALSGHDVTV
                     LLPAIYLMGNPVQNVGRCLGTAEVNAKYYPHIIAVCAINALLSIWVMQLIV"
     gene            1714..2886
                     /locus_tag="OPY25_004285"
     CDS             1714..2886
                     /locus_tag="OPY25_004285"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCS0929738.1"
                     /translation="MPDLSAAEFTLLQGAHLFAPEDRGICDVLLANGKIIAVGADIPG
                     DIVPDCAVINLSGRMLCPGFIDQHVHLIGGGGEAGPTTRTPEVSLSRLTEAGITTVVG
                     LLGTDSVSRHPASLLAKTRALNEEGITAWMLTGAYHVPSPTITGSVEKDVALIDRVIG
                     VKCAVSDHRSAAPGGNQLASMAAESRVGGLLGGKPGVSVFHMGSSKKGLQPLYDILEN
                     SDVPIGKLLPTHVNRSESLFEQALAFALKGGVIDITTSIPDPVAPAEGIARAVKAGVP
                     LSRVTLSSDGNGSQPLFDAAGNLTGIGVAGFESLLETLQTLVNHYGFSLTDALRPLTT
                     SVAAFLSLDGKGEIRPGNDADLLVFSADLRIEQVYARGKRMVNEGKACVKGTFEPA"
     gene            3005..3913
                     /gene="hypT"
                     /locus_tag="OPY25_004286"
                     /gene_synonym="qseD"
     CDS             3005..3913
                     /gene="hypT"
                     /locus_tag="OPY25_004286"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HCS0929739.1"
                     /translation="MDVTGAGLHNIETKWLYDFLTLEKCRNFSQAAIIRNVSQPAFSR
                     RIRALEHAVGVELFNRQVSPLQLSEQGKIFHSQVRHLLQQLESNLTELRGGSDYTLRK
                     IKIAAAHSLSLGLLPTIVKQMPTQFTYAVEAIDVDQAVDMLREGQSDFIFSYHDENLQ
                     QAPFDNIRLFESRLFPVCANNGRGEPRYTLEQPHFPLLNYSQNSYMGRLINRTLTRHA
                     ELSFSTFFVSSMSELLKQVAMDGCGIAWLPEYAIRQEITDGRLIVLDADELVIPIQAY
                     AYRMNTRMSQVAETFWRDLRGLQAAL"
     gene            complement(3919..4653)
                     /locus_tag="OPY25_004287"
     CDS             complement(3919..4653)
                     /locus_tag="OPY25_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HCS0929740.1"
                     /translation="MKHTIGILGGMGPAATADMLEKFVELRHVSCDQQHIPLIVSSIP
                     DIPDRTACLLSGGPSPYRYLERYLHMLEDAGAECIVIPCNTAHYWFDDLQNVAKARMI
                     SILDATLGDIPPSARHVGLLATNATLATGLYQKKALARGLTLIQPEDAGQALVMQAIY
                     TLKRGDKTAAQALLLPQIDSLIARGAQAIIMGCTEIPLIVAGHERAIACPMIDSTASL
                     VRAAIRWYESWPDTRASLTGEQRLTA"
     gene            complement(4892..5422)
                     /locus_tag="OPY25_004288"
     CDS             complement(4892..5422)
                     /locus_tag="OPY25_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463368.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HCS0929741.1"
                     /translation="MAGKWNVLSLLAFRPCQPALPHDNHGGGMDAIYLKLDGIEGESQ
                     IKGFENQIKLIAYNHNPTKRESGEARGTYIGGLTLTKPVDLATLGLYEHYCNGKTVKE
                     GVLTLCRSDKGAMLPFIIYTLTNVRISRMSNHGDAEGSATETVDLVYSHIRWDIPALA
                     SKSKTRRPLHRQALWR"
BASE COUNT         1222 a         1552 c         1439 g         1372 t
ORIGIN      
        1 catccatggg cctcgccctg acgggccgtt gctcacccca gtcacatcgt tattatgctc
       61 ctggggactc actcccttgc cgcctttacg caactcgaat tattttggct atatattcca
      121 ttatgatgat tatcgctccc tctcaaatca tcacaattat aaataaatca catcatgaaa
      181 ttaattcgat tattcgtttt ttattacctg cccgtaggat tcttagggcg caagctgacc
      241 catcagcggc tactgacctg accgtgacaa ttcctcttaa ggcgtgaaat tgactaacgt
      301 caaatttatt tccccttttt cctgctcccg gctctggcct gcgtcaacac ctgtttcttt
      361 gcttttttac cgcgcgttat accgtccacg gttccccgcg cctccggcag tagcgaggat
      421 ggtgattttt cgcgctgcta tgcaagaaac gcatagcacg atacatactt gcattttgtc
      481 cttaccctta tggctgataa ggtctttctg tttcgggctt tttggcctgt ggctacaacc
      541 aacacatcat caaaaaaatt cggggatcgc tatggcgcaa caagtggacg gggcggccat
      601 gccgcttgat acagaaaagg tcgggataaa gggatacctg gcgttttttc tcaccattat
      661 tttcttttcc ggcgtatttt ccggaagcga aggctggtgg cgcgtttttg attttaccgt
      721 actcaacggg tcattcggtc atgtgaccgg tacgcagacc tttcgcggcg cgggcggaac
      781 gggcgcgaaa gatggcttcc tttttgcgct ggagctggcg ccgtcggtta tcctttctct
      841 gggtatcatc gcgattacgg atgggcttgg cggtctgcgg gcggcacagc aattgatgac
      901 gcccatcctg aaaccattgc ttggcattcc cggcatttgc tcactggcgc tgatcgccaa
      961 cctgcaaaat accgacgccg cggcgggtat gaccaaagag ctggcgcagg aaggcgaaat
     1021 caccgaacgc gataaagtga tttttgccgc ctggcagacc agcggcagcg ctattatcac
     1081 caactatttc tcctccggcg ttgcggtatt cgcctttctg ggaacgtcag tcatcattcc
     1141 gctggtggtc attctgctat tcaaatttat cggcgcaaac cttttgcgca tctggattaa
     1201 catcgaagaa cgccgtcacc ctgcgcaagg agcccaatca tgacgactca ggtacgtaag
     1261 aatgtcatgg atatgtttat cgatggcgca cgccgcggtt ttaccatcgc cacgaccaac
     1321 ctgttaccca atgtggtcat ggcatttgtc attattcagg cgctgaaaat taccggtctg
     1381 ctcgactggg taggccatat ctgccagccc gtgatggcgt tgtgggggct tcccggcgaa
     1441 gcggctacgg tgcttctggc ttcgctgatg agtatgggcg gcgccgttgg cgtggcggcc
     1501 agtctggcta ccgccggcgc gctaagcggc cacgatgtta ccgtactact gccagccatt
     1561 tacctgatgg gaaacccggt acagaatgtc ggccgctgtc tcggtactgc cgaagtcaac
     1621 gccaaatatt acccgcatat tatcgcagtc tgcgccatca atgcgctgct gtcgatctgg
     1681 gtcatgcagc ttattgttta ataaggagtt atcatgcctg atttatccgc cgcggagttt
     1741 accttgttac agggtgcgca cctgtttgcg ccagaagacc ggggcatctg cgatgttctg
     1801 ctcgcgaatg gcaaaattat tgccgtcggc gctgacatcc ccggcgatat cgtaccggac
     1861 tgtgcggtga ttaatcttag cggtcgtatg ctgtgcccgg gctttatcga ccaacacgtt
     1921 catctgatcg gcggcggcgg cgaagcgggg ccgacgacgc ggacgccgga agtctctctg
     1981 agccgcctga cggaagccgg gataacaacg gtcgtcggcc tgcttggcac cgactccgtc
     2041 agccgtcatc ccgcgtcgct gttagccaaa acgcgagcgc taaatgagga ggggatcacc
     2101 gcctggatgc tcacgggcgc ttatcacgtt ccgtcgccga ccattactgg ctcggtagaa
     2161 aaagacgtcg cgctgatcga tcgcgtcatt ggcgtgaaat gcgcagtctc cgaccaccgt
     2221 tccgccgcgc ccggcgggaa tcaactcgcc agcatggcag ccgaatcacg cgttggcggc
     2281 ctgctgggcg gcaaacccgg tgtcagcgtt tttcatatgg gcagcagcaa aaaagggtta
     2341 cagccgctgt atgacatcct ggaaaacagc gacgtgccga tcggtaaact gctgcctacc
     2401 cacgtcaacc gtagcgaatc gcttttcgag caggcgctgg cgtttgcgct taaaggcggc
     2461 gtgatcgaca ttaccaccag tatcccggat cccgtcgcgc cggcggaggg cattgccaga
     2521 gcggtaaaag ccggcgtccc gctttcccgg gtgacgctca gttcagacgg caacggcagc
     2581 cagccgctat ttgacgctgc cggaaatctg acgggtatcg gcgtcgcggg cttcgaaagt
     2641 ttgctggaga cgttgcagac gctggttaac cactacggat tcagcctgac cgatgctctg
     2701 cgtccgctga caaccagcgt agccgccttc ctcagtctgg acggcaaagg cgaaatccgt
     2761 cccggtaacg atgcggatct gctcgtcttt agcgcagatt tacgcattga gcaggtgtat
     2821 gcgcgcggca aacgcatggt caatgagggg aaagcctgcg taaaaggtac ctttgaaccg
     2881 gcgtaattcc cgctagtttc agactgcccc atcacggcat tctgaaagag gacgggataa
     2941 gtggttgtca gccgcccgaa tggacgtaga atgccccttc ggacggctga caggataacg
     3001 gtaaatggat gtaactggag caggtttgca caatattgag acaaaatggc tatatgattt
     3061 tctgacgctg gaaaagtgcc gcaatttctc tcaggccgcc attatccgca acgtatcgca
     3121 acccgctttt agccggcgga ttcgcgccct ggaacatgcc gtgggcgttg aactgtttaa
     3181 ccgacaggtc tcgccgctac agctttccga acagggtaaa atctttcact cccaggttcg
     3241 ccacctgtta cagcagctgg aaagtaatct gaccgaactg cgcggcggca gcgattatac
     3301 gctgcgtaaa atcaagattg ccgccgccca ctcgctctcc ctcggcctgt taccgaccat
     3361 cgttaagcag atgccgacgc agtttaccta cgccgttgag gcgatagatg tcgaccaggc
     3421 ggtggatatg ttacgtgagg ggcaaagcga ttttatcttt tcctatcacg atgaaaacct
     3481 gcaacaagcg ccgtttgata atatccgcct gtttgagtcg agactgtttc cggtttgcgc
     3541 caacaatggc cggggcgagc cgcgctatac gcttgagcag ccgcactttc ccctgcttaa
     3601 ttacagtcaa aactcctata tgggccggct gataaatcgt accctgactc gccatgctga
     3661 actgagtttc agtacatttt tcgtctcttc gatgagtgaa ttgttaaaac aggttgcgat
     3721 ggacggctgc ggaatcgcct ggttacccga gtatgctatc cgtcaggaga ttaccgacgg
     3781 gcgcctgata gtgcttgatg ccgacgaact ggttatcccg atccaggctt atgcttatcg
     3841 catgaatacc cgcatgagtc aggtagccga aacattttgg cgcgacctgc gtgggcttca
     3901 ggccgcgctg taaacacatc aggcggtaag gcgttgttcc ccggtcaaag aggcgcgggt
     3961 gtctggccag gactcatacc aacgaatcgc cgcgcgcacc agcgacgctg tggaatcaat
     4021 catcgggcac gctatcgcgc gttcatgtcc ggccacaata agcggaattt cggtacaccc
     4081 cataataatt gcctgagcgc cacgggcaat aaggctatcg atttgcggca gcagcagcgc
     4141 ttgcgccgca gttttatcgc cacgtttaag cgtataaata gcctgcatta ccaacgcctg
     4201 ccccgcgtct tctggctgaa ttaacgtcag cccccgcgcc agcgctttct tttgatataa
     4261 cccggttgcc agcgtcgcat tggtcgccag cagaccaacg tgccgcgccg atggcggaat
     4321 atcccccagg gtggcgtcca ggatgctgat cattcgcgct ttcgcgacgt tctgtaaatc
     4381 atcaaaccaa taatgcgcag tgttgcatgg gataacgata cactccgccc cggcgtcttc
     4441 cagcatatgc agataacgct ccagataacg gtatggcgaa ggcccgccgg ataacagaca
     4501 tgctgtacga tcgggaatat cagggataga gctgacaatg agcgggatgt gttgttgatc
     4561 acaactgaca tgtcgcaatt caacaaattt ttccaacata tccgccgttg ccgcaggtcc
     4621 catccccccc agtatcccaa tggtgtgttt catcgctttt cccgcttatt tacgtcaagg
     4681 tcagaaacac actatcaact tgatgtgtat ataaaaaatg ccgttttatt agcggctatg
     4741 cgtaaaaatc ataacgggtg taagggccat gcgttatcgc cttttcaggc aatcgattgg
     4801 ttacatgagc gctcatcagc cttcgcaagc cgctaaatgc catttcgcta tacagcatcg
     4861 cccactgcga gtccgcaagc ttgttttgtc ctcatcgcca cagcgcctgt cggtgaaggg
     4921 gccgccgtgt tttgcttttc gacgccaatg cgggaatatc ccagcgaata tggctataaa
     4981 ccaaatccac ggtctccgtg gcgctgcctt cggcgtcgcc atgattgctc atgcgtgaaa
     5041 ttcgcacatt ggtgagcgta taaataataa atggcagcat tgcgccctta tcactacggc
     5101 ataatgtcag cacgccttct ttcaccgttt tcccgttaca atagtgctca tagaggccaa
     5161 gcgtagcaag atcgactggc tttgtcagcg tcaaccctcc aatatatgtc cctctcgctt
     5221 cgccggactc ccgtttcgtc gggttgtggt tgtaagcaat aagttttatt tggttttcaa
     5281 aacctttgat ctggctttcg ccttcaatac cgtccagttt taaatagatg gcgtccatcc
     5341 cccctccgtg attatcatgc ggcaaagcag gctgacaagg acggaacgcc aacaatgaaa
     5401 gaacgttcca ttttccagcc atttcgttgg tgtctctgta taccagatta aataccgaca
     5461 atctgctata actggattct tgctaaatac cttctgccat caacaatcca ttttacaata
     5521 gcgctactga cctgaaatct attacgcctg gcattcaagc atcgtttcct gaataaccat
     5581 agccg
//
LOCUS       DAJVKX010000203         5512 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.203, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000203 DAJVKX010000000
VERSION     DAJVKX010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5512
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.203"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(86..184)
                     /locus_tag="OPY25_004289"
     CDS             complement(86..184)
                     /locus_tag="OPY25_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HCS0929742.1"
                     /translation="MRVGVLFPVVIFITAILFLAWFFIGGYAAPGA"
     gene            380..631
                     /locus_tag="OPY25_004290"
     CDS             380..631
                     /locus_tag="OPY25_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HCS0929743.1"
                     /translation="MKFTWIALPGVLLLSACSSSQPNAPRPPRIGMPNPAAVYCEQQG
                     GTLMPVQTPQGVRSDCKLPNGEIIDEWALWRREHPDTKK"
     gene            700..1011
                     /locus_tag="OPY25_004291"
     CDS             700..1011
                     /locus_tag="OPY25_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929744.1"
                     /translation="MFQLKPGALAIVIGAKTPAGRRNIGKSVELFCLCQPGDEFINPV
                     NGHVTLLPKEAPRALWLVTGDVASADGQHGFAWVRAEHLMPLSPDRQPGQAAARQSQL
                     S"
     gene            complement(997..1344)
                     /locus_tag="OPY25_004292"
     CDS             complement(997..1344)
                     /locus_tag="OPY25_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HCS0929745.1"
                     /translation="MRIQCKRVYFPAEKDDGYRVLVDRLWPRGIKKAALVYDEWNKAI
                     TPSTELRKAFHSELIDFNHFAQQYRAELAQQHQEGKRLADIARHQPLTLLYAAKDTRQ
                     NHAIVLAEWLREL"
     gene            complement(1463..2647)
                     /locus_tag="OPY25_004293"
     CDS             complement(1463..2647)
                     /locus_tag="OPY25_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HCS0929746.1"
                     /translation="MTTALSPRGKQGALLIAGILMIATTLRVTFTGAAPLLETIRTDY
                     GLSTAQTGLLTTLPLLAFALISPLAAGIARRFGMERSLFAAMLLICAGIALRSLPSAA
                     LLFAGTAIIGCGIALGNVLLPGLIKRDFSQHVARLTGAYSLTMGAAAALGSALVVPLA
                     LHGFGWRSALLMLMLFPLLAFLIWLPQWRTTRSANLSSSRALHERGIWRSPLAWQVTL
                     FLGLNSLIYYVIIGWLPTILISHGYSEAQAGSLHGLLQLATAAPGLAIPLILHRFNVQ
                     RWIAALVSLLCALGAAGLWFVLGQAIIWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPVMGKLHDASGSWYLPLSGVTVLAIIMAIFGLYAGRDREI
                     AS"
     gene            2748..3542
                     /locus_tag="OPY25_004294"
     CDS             2748..3542
                     /locus_tag="OPY25_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929747.1"
                     /translation="MIGLRLDGYDPDLHHDAAVAFCIRARDDELFSPRHQHRKGQLIL
                     ALHGAITCEVENAMWMVPPQYAVWLPGSLPHSNHVTAGAELCFLFIEPAAVVMPERCC
                     TLKISPLCRELILSLARRTDSERAQMPTQRLIQVLFDELPQQPQEQLQLPVSGHPKIR
                     QMVETMAQEHARWNTLGQWASVFAMSERNLARLVVKETGLSFRRWRHQLQLILALQAL
                     IAGRNVQQTAQMLGYDSTTAFITMFKKGLGQTPGQYLTGELLLSHN"
     gene            complement(3522..3968)
                     /locus_tag="OPY25_004295"
     CDS             complement(3522..3968)
                     /locus_tag="OPY25_004295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460246.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCS0929748.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLNTFFP
                     WIEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRG
                     ITLMGNQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            4174..4275
                     /locus_tag="OPY25_004296"
     CDS             4174..4275
                     /locus_tag="OPY25_004296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929749.1"
                     /translation="MYDPPFLEALMITASFFAIFIIIVVSVLLLEGD"
     gene            complement(4272..4790)
                     /locus_tag="OPY25_004297"
     CDS             complement(4272..4790)
                     /locus_tag="OPY25_004297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCS0929750.1"
                     /translation="MAEVAKGVATHQRLVALLTQENARYRVVSHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHLGGLRASLASPAEVDML
                     TGCVFGAIPPFSFHPNLKLVADPLLFERFDEIAFNAGLLEKSVIMNTQDYLRIARPEL
                     AVFRRFQSSPTA"
     gene            complement(4840..>5512)
                     /locus_tag="OPY25_004298"
     CDS             complement(4840..>5512)
                     /locus_tag="OPY25_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCS0929751.1"
                     /translation="IINKSKNNLFQYVNYNHDIPGGLRVSLSLDLTYFLVSSWKALAF
                     YLLATALLLNMVRMHFRLYRNVTRENISDAMTGLYNRKILTPVLEQRLQRLVNTGTPV
                     TFVAIDCDRLKLINDTLGHQEGDRIITLLAKAIKTSIRKSDYAIRLGGDEFCIILVDY
                     AADLAIHLPERIIRNLQIIAPDKTVHFSAGIYNMQPNDTINDAYQASDAQLYLNKQQK
                     QHRSS"
BASE COUNT         1385 a         1432 c         1470 g         1225 t
ORIGIN      
        1 aaatgaattt accaccagcc cagttcggta cccgccaccg caattagcgc gatgcccatc
       61 aacaccatcg ttgttttcct catggttatg ctcccggtgc ggcgtaaccg ccaataaaaa
      121 accatgccaa aaataatatt gccgtaatga aaatgacgac agggaagagg acacccactc
      181 tcatgctatt accttcactg ttcagggggc gccagaatag cagggttttc tcagcgacaa
      241 aaggttggtt gctttgtgac agggcgtggc tattgctgac ttaacccggg ataaacaccc
      301 actaaagcgc tgacagaaag tatggaaata gcgtacccgc caggttatcc tggacaaaat
      361 atcgctttaa ggagtcgtta tgaaatttac gtggattgcg ttgccaggcg tattgctgct
      421 gagcgcttgt tcatcgtcgc aacccaacgc ccccaggccg ccgcgtattg ggatgcctaa
      481 tccggcagcc gtctactgtg agcaacaggg cggtacgctg atgccggtgc agaccccaca
      541 aggcgtgcgt tccgattgca aattgcccaa tggcgaaatc attgatgagt gggcattatg
      601 gcgcagagag caccctgata cgaaaaagtg acaacctgcg gtccgacggg atatgattaa
      661 gaacaatctg ataatgagtt tcatgcggcg caagaaaata tgtttcagtt aaagccgggc
      721 gcgttggcaa tagttattgg cgctaagaca cccgccggac ggcggaatat tggtaaatcg
      781 gttgagctat tttgcctgtg ccaacccgga gatgaattca ttaatccggt aaatggacac
      841 gtcaccttac tgccgaaaga agcgcctcgg gcgctgtggc tggttacggg cgacgtagcc
      901 tccgccgatg gtcagcacgg ttttgcctgg gtgcgagcag aacatttgat gccgttgtcc
      961 ccggacagac aaccaggcca ggcggcggca cgacaatcac agctctcgta gccactctgc
     1021 cagcacaatg gcatggttct ggcgagtatc tttagcggcg tatagcaacg ttagcggttg
     1081 gtgtcgggca atatccgcca gacgtttgcc ttcttgatgc tgttgcgcaa gttctgcccg
     1141 gtattgctgc gcgaagtggt taaaatcaat cagttcgcta tgaaaggctt tgcgcaattc
     1201 ggtggagggc gtaatggcct tattccattc atcatagacc agcgctgctt ttttaatgcc
     1261 tcgcggccat agcctgtcaa ccaatacccg ataaccatcg tctttttccg ccgggaaata
     1321 gacgcgctta cactggattc gcatttttcc ctcctgtgat ggtgtcgctt acggtacttt
     1381 tgtcggatag cagtaatgat tttaatggat caggcctgat aaacgaagcg tcatcaggca
     1441 ttcaagtggg tatcaggttt atttatgacg ctatctctcg atcgcgtccg gcgtagaggc
     1501 cgaaaatcgc catgatgata gccagaaccg ttacgcccga tagcggcaga taccagctac
     1561 cgctggcatc atgaagtttt cccatgacgg gcggcccaca tgccgccagt aaatacccga
     1621 ccgactgcgc catgccggaa agcgccgccg cctgatgcgc cgaactggcg cgcaggccga
     1681 taaacgtcag gccgaggatc atcgtcgcgc ctgaaccgaa gccgaacagt agcgtccaga
     1741 tgatcgcctg gcccagcaca aaccaaagcc ccgccgcgcc cagtgcgcac aatagtgaga
     1801 ccagcgcggc aatccagcgt tgaacgttaa agcgatgcaa aataagcgga atagctaacc
     1861 caggcgccgc ggtcgccagt tgcagcaggc catgtagcga tcctgcctgt gcttcgctgt
     1921 aaccgtggct gatgagtatt gttggtaacc agccgataat cacataataa atcagtgagt
     1981 taagcccaag aaacagagta acttgccagg ctaaaggcga acgccagata ccgcgttcat
     2041 gtaatgcccg ggagctactc aggttagctg agcgggtagt gcgccactgc ggcaaccaga
     2101 taagaaacgc caacagcgga aacagcatca gcattaacag cgcgctgcgc cagccaaaac
     2161 cgtgcaacgc cagcggaacc accagcgcag accccaacgc ggcggcggcg cccatcgtca
     2221 atgagtacgc gcccgtcagc ctggcgacat gttgtgaaaa atcgcgctta atcaatcctg
     2281 gtagcagcac attacccagc gctatcccgc acccaataat ggcagttccg gcaaacaaca
     2341 atgcagcgga gggcagggag cggagagcaa tacccgcgca aatcagcagc attgcggcaa
     2401 acagactgcg ttccatccca aaccggcggg caataccggc cgccagcggc gaaatcagtg
     2461 caaacgccag aagcggcaag gttgttagca ggcccgtctg ggcggtggaa agaccgtaat
     2521 ccgtacggat tgtctccagc aacggcgcag cgccggtaaa tgttacgcgt agcgtagtgg
     2581 ctatcatcaa aataccggca atcagtaaag cgccctgttt gccgcgtggt gaaagggctg
     2641 tcgtcatcgt tttctcatct cgtcaggcga ggcgatacct taacagtttt tactgtttgg
     2701 atgaatcaag ctaaaatgac aatttatcgc taaaatcgga caatataatg attggcctga
     2761 gactggacgg ttacgatccc gaccttcacc acgatgccgc tgtggccttt tgtattcgcg
     2821 ccagggatga tgaactgttt agccctcgcc atcagcatcg caagggacag ttgatcctcg
     2881 ctctgcacgg cgcgatcacc tgtgaggtgg aaaatgcgat gtggatggtt ccgccccagt
     2941 atgccgtctg gctccccggc tcgctgccgc acagtaatca tgtgaccgca ggggcggagc
     3001 tgtgcttttt atttattgaa cctgcggcgg tcgtcatgcc ggagcgttgc tgcacgctga
     3061 aaatttcgcc gttatgccgg gagttgattt tgtcgctggc gcgcagaacc gattccgaaa
     3121 gagcgcaaat gccaacgcag cgccttattc aggtgttgtt tgatgaactg ccgcagcagc
     3181 cgcaggaaca attgcaatta ccagtatcgg ggcatccgaa aattcgccaa atggttgaga
     3241 caatggcgca ggagcacgcg cgatggaata cgttagggca gtgggccagc gtattcgcga
     3301 tgagcgagcg taaccttgcc cggctggtcg tcaaagagac gggactcagc tttcgtcgct
     3361 ggcgtcatca attacaatta attctggcgc tacaagcgct gatcgcggga cgtaatgtac
     3421 aacagacggc gcaaatgctg ggttatgatt ctaccacggc attcattacg atgtttaaaa
     3481 aaggcctggg gcagacccca ggccagtatc tgacgggcga gttactgctt tcccacaatt
     3541 aaagagacca gccccgccgc aatcagtggg ccgaccggca cgccgcgaaa cagcgcgacg
     3601 ccaagtaccg taccgaccag cagcccggcg acgagctgcg gttggtttcc catcagcgta
     3661 atgccgcgac cacccagcca ggagacgaaa acgccgacgg caatcgcgac cagcgatttc
     3721 cagttcacaa aagagtggat caatgtggag ggcggtaggg ttccgctggc gatgggggcc
     3781 atcacgccga tggtcagaat gataatcccg acggtgagcc cctgtttttc aatccaggga
     3841 aaaaaggtat tcaacggggt tacgcggaca ataatcagca ccagaattga gacggcgaca
     3901 gtggtgttgt ggctaataaa tcccagagct gccagtccga gcaggatcag cagagtgaca
     3961 tcaaacatta tggtttcctt gccaaaaagt aagcctgact actttacgcc caaacggcaa
     4021 agcgcacagg cctttttaac gattgatgcg gatttcaggc aactgcctga aagacaattt
     4081 ctacgtgaaa aacggcgttg tcattaaatt gacatcaacg ccgcgtattg ctaaccggtg
     4141 aaccgtcatt gttgtcttcc tgaggataca attatgtacg atccaccgtt tcttgaagcg
     4201 ctgatgataa cagcgtcgtt tttcgccatt tttatcatta ttgttgtgtc tgtattgctc
     4261 cttgaagggg actaagccgt tggcgatgac tgaaagcggc ggaagactgc cagttctggt
     4321 cgggcgatgc gcagatagtc ctgtgtattc ataatgactg atttttccag cagaccggca
     4381 ttaaaggcaa tttcatcgaa acgctcaaac aggagcggat cggcgaccag tttcagattg
     4441 gggtgaaaac tgaaaggcgg gatcgcgcca aaaacgcagc cggtcaacat atcgacttcc
     4501 gccgggctgg caagggaagc gcgtaagccg cccagatgtg aagcaagctg agagaggtcg
     4561 gcttgctgat cggccgccag aatagcaaga acgtgctggt tgacgccgtt gcctttgact
     4621 ttacagacca gcgcttttgc gccctggccc agcgcagtac cgcgtatttc agataccgct
     4681 tcgcattttc ctactgcttc atggctcacc acacgatagc gcgcgttctc ctgggttaat
     4741 aaagccacta aacgttggtg tgtagcgaca cccttcgcga cttcagccat ttcggccatt
     4801 tcttcctcct ggtacaatat gaacatttac tgcgaagcac tatgatgaac gatgttgttt
     4861 ttgttgtttg ttcagataga gctgcgcatc ggaagcctgg taggcatcat taatcgtatc
     4921 attgggctgc atattataaa tcccggcgga aaaatggact gtcttatccg gtgcgataat
     4981 ctgcaggtta cgaataatac gctccggcag atggatagcc aaatccgccg cgtaatcaac
     5041 aagaataata cagaattcat cgccgccgag gcgaatggcg taatcgcttt tacgaatcga
     5101 tgttttaatc gctttcgcca acagggttat aattcggtcg ccttcctggt gccccagggt
     5161 atcgttgatc agttttaacc tgtcgcaatc aatagcgaca aatgtcaccg gcgtcccggt
     5221 attgaccagg cgttgcagtc gctgttccag caccggtgtt aatattttac ggttgtaaag
     5281 cccggtcatg gcatcgctaa tattttcgcg tgtgacgttg cgataaagcc gaaagtgcat
     5341 ccgtaccata ttaagcagga gcgctgttgc cagtaagtaa aaggccagcg ctttccagga
     5401 cgagacaagg aaataggtta aatcaagcga caacgaaacg cgcagtccac cagggatatc
     5461 atggttataa ttcacatatt gaaacagatt atttttgctt ttattaataa ta
//
LOCUS       DAJVKX010000204         5506 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.204, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000204 DAJVKX010000000
VERSION     DAJVKX010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5506
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.204"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(40..2676)
                     /gene="gyrA"
                     /locus_tag="OPY25_004299"
     CDS             complement(40..2676)
                     /gene="gyrA"
                     /locus_tag="OPY25_004299"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HCS0929752.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHGLMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYMRARAEVEADAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDP
                     IIELIRRAPTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREEMEL
                     IRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLP
                     LEANERITAILPVREYEEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDEL
                     IGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKLAGDDKVVSLIIPRG
                     EGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVT
                     EGDEDIAPEAESDDDVADDADE"
     gene            complement(3086..4288)
                     /locus_tag="OPY25_004300"
     CDS             complement(3086..4288)
                     /locus_tag="OPY25_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HCS0929753.1"
                     /translation="MKITSIEVFDCELKKRDQTMSSYNPVLIRVNTDSGLSGIGEVGL
                     AYGAGAKAGVGIIRDLASLIVGEDPLNIEKIWEFFFRKTFWGMGGGNVFYAGMSAIDI
                     ALWDIKGKYLGVPVYQLLGGKTNEKLRTYASQLQFGWGDKRQILVTPEEYAEAARAAL
                     DDGYDAIKVDPLEIDRNGDDCVFQNRNRNYSGLLLADQLKMGEARIAAMREAMGDDAD
                     IIVEIHSLLGTNSAIQFAKAIEKYRIFLYEEPSHPLNSDNMQKVSRSTTIPIATGERS
                     YTRWGYRELLEKQSIAVAQPDLCLCGGITEGKKICDYANIYDTTVQVHVCGGPVSTVA
                     ALHMETAIPNFIIHEHHTNAMKASIRELCTHDYQPENGYYVAPEQPGLGQELNDEVVK
                     EYLAYVIK"
     gene            complement(4303..5506)
                     /locus_tag="OPY25_004301"
                     /pseudo
     CDS             complement(4303..5506)
                     /locus_tag="OPY25_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461216.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         1391 a         1490 c         1242 g         1383 t
ORIGIN      
        1 aaaaagggcc ggatatccgg ccctcgcaca gcaataatat tactcgtcag cgtcatccgc
       61 aacgtcgtca tcgctttccg cttccggggc gatatcctca tccccttccg tcacgctgcc
      121 gtcgatagca tcgagttctt cgtcatctac cggttcagca acgcgttgca gacccactac
      181 gttttcatct tccgccgtgc ggataaggat aacgccctgg gtattacgtc ccaccacgct
      241 gatctcagac actcgggtac gcaccagagt accggcatcc gtgatcatca tgatctggtc
      301 gcaatcgtct acctgtaccg caccgacaac ggaaccgttg cgctcggtca ctttgataga
      361 gataacgccc tgcgtcgcac gagacttggt cgggtactcg tccgctgcgg tacgcttccc
      421 gtagccgttt tgcgttacgg tcagaatagc gccttcgccg cgtgggatga tcagagaaac
      481 tactttatcg tctcccgcca gcttaatacc gcgcacaccg gtcgcggtac gccccatcgc
      541 acggacggcg tcttctttga agcgcaccac tttacccgcg gccgagaaca gcatgacttc
      601 gtcagaacca gaagtcaggt caacgccaat cagctcgtcg ccgtcgttga ggtttaccgc
      661 gataataccg gcggaacgcg gacggctgaa ttcggtcagc gccgttttct tcacggtacc
      721 gctggcggtc gccataaaga cgttgacgcc ttcttcgtac tcacgaaccg gcagaatcgc
      781 ggtgatacgt tcgttggctt ccagcggcag caggttaacg atcggacgac cgcgcgcgcc
      841 acggctggct tccggcaact gatagacctt catccagtac agacggcccc ggctggagaa
      901 gcaaaggatg gtgtcatggg tgttggccac cagcaggcgg tcgataaagt cttcttcttt
      961 aatacgtgct gctgatttgc ctttaccgcc acgacgctgt gcttcgtaat cggttaacgg
     1021 ctgatatttc acatagccct gatgagacaa ggttacgaca acatcttcct ggctaatcag
     1081 atcttcgata ttaatatcgg cgctgttggc ggtgatttcg gtacgacgct catcgccgaa
     1141 ctgatcgcga attaactcca tctcttcgcg gatcacttcc atcaggcgat cggcgctgcc
     1201 cagaatgtgc agcagttcag cgatctgctc cagcaactct ttgtattcgt cgagcagttt
     1261 ttcatgctcc aggccggtca gtttctgcaa acgcagatcc agaatcgcct gcgcctgctg
     1321 ttcagtcagg tagtattgac cgtcacgcac gccaaattct ggctccagcc attccggacg
     1381 cgcggcgtcg tcaccggcgc gctccagcat cgcagcaacg ttgcccagat cccacggacg
     1441 cgaaatcagc gccgctttcg cttccgccgg cgtcggcgcg cggcgaatca gttcgataat
     1501 cgggtcgatg ttggccagcg caatcgccag agcttcaagg atatgcgcac gatcacgggc
     1561 tttacgcagt tcaaaaatag tccgacgcgt caccacttca cggcggtggc gcacgaacgc
     1621 tgaaataata tctttcaggt tcatgatctt cggctggccg tgatgcagcg ccaccatgtt
     1681 aataccgaag gaaacctgta gctgggtctg ggagtagaga ttattaagca ccacctcgcc
     1741 caccgcatcg cgtttcactt caatcacgat gcgcatcccg tctttgtcgg attcgtcacg
     1801 cagcgcgctg atgccttcca cgcgtttatc tttcaccagc tcggcgattt tctcgatcag
     1861 gcgcgctttg ttcacctgat agggaatttc atggacgatg atggtttcac ggcccgtttt
     1921 cgcgtcagct tcaacttccg cgcgggcgcg catgtacact ttgccacgac cggtacggta
     1981 ggcttcttcg ataccacgac gaccgttgat gatcgcggcg gtcgggaagt ccggacccgg
     2041 aatatgttcc atcagccctt caatgctgat gtcttcgttg tcgatatacg ccaggcagcc
     2101 gttaatcact tccgtcaggt tgtgcggcgg gatattcgtc gccataccta ctgcgatacc
     2161 ggaagaaccg ttcaccagca gattcggaat tttggtcggc atgacgtccg gaattttttc
     2221 cgtaccgtca tagttatcca cgaaatccac cgtctctttt tcgagatcgg ccatcagtcc
     2281 gtgggcgatt ttcgccagac ggatctccgt ataacgcatt gccgccgcgg agtcgccgtc
     2341 aatagaaccg aagttaccct gaccatccac cagcatgtaa cgcagcgaga atggctgcgc
     2401 catacgaacg atggtgtcat acactgcgga atcgccgtgg ggatggtatt taccgattac
     2461 gtcaccaacg acacgggcag attttttata ggctttgttc cagtcattgc ccaatacgtt
     2521 catggcgtaa agtacgcgac ggtgtaccgg cttcaggcca tctcggacat ccggcagcgc
     2581 acggccaaca atgacagaca tcgcataatc cagataggag ctcttcagct cttcctcaat
     2641 gttgaccggt gtaatttctc tcgcaaggtc gctcatctaa ccgctatccc tctactgtat
     2701 cccggattca aaggtcgcaa attataacac attcgcccac gtactggtaa acggaatgca
     2761 gccagacaat gctttattcg ggtgccacat gctctcttca tttataagcg tggtctcggc
     2821 gtttatcggc gatcagcttc agaggcgaca cagaggagat ctgggcctgg ccaggaatag
     2881 gctggaaaat caatacctcc cgtgtatacc cgtcatactt caagtttcat gtgcgttggc
     2941 ggcaagttac tcggcccatc cctgggcctc gccccgtcgg ggttagcgca agcgctgttc
     3001 aagacggtta accattttat cctgcaactc gaattattta ggggatatgc cgggaggcat
     3061 aaaccataat cagtatcacc agatgctatt taatcacata ggccaggtat tctttcacta
     3121 cctcatcgtt taattcctga cccaatccgg gctgttccgg cgcgacataa tagccatttt
     3181 ccggctgata atcgtgggta caaagttccc gaatagatgc tttcatcgca ttggtatgat
     3241 gttcatgaat aataaagttg ggaattgccg tttccatatg cagcgcggct accgtggaaa
     3301 caggaccgcc gcaaacatgc acctgtacag tggtgtcata aatattagca tagtcacaga
     3361 ttttctttcc ttcggtaatt ccgccgcaga gacacaaatc aggttgcgct acggcaatag
     3421 actgtttctc cagtaattcc ctgtatcccc atcttgtgta ggaacgctcg ccagtggcga
     3481 ttggaatcgt tgttgaacgg gaaactttct gcatattatc agaatttaat ggatggctcg
     3541 gttcttcata aagaaagata cgatactttt ctatcgcctt cgcaaattga atagctgagt
     3601 ttgtaccgag aagagaatgg atttctacga taatatcagc atcatccccc attgcttcac
     3661 gcatagcggc aattcgcgct tcccccattt ttaattgatc ggccagtaac aatcctgaat
     3721 agttacgatt tctattctga aaaacacagt catcgccatt acgatcgatt tcgagtggat
     3781 ccactttaat cgcatcatat ccatcgtcaa gagccgcacg cgccgcctca gcatattcct
     3841 caggtgtcac taatatctgg cgtttatccc cccaaccaaa ttgtaactga ctagcatagg
     3901 ttcttaattt ttcattagtt ttcccgccaa ggagctgata aacaggtaca cctaaatatt
     3961 tacctttgat atcccaaaga gcaatatcaa tagcgctcat tccggcataa aaaacgttcc
     4021 cgcctcccat tccccaaaaa gtctttctga aaaagaactc ccaaattttt tcgatattta
     4081 atggatcttc acccacaatc aatgacgcca gatctctgat gatccctacg ccagctttag
     4141 cgcctgcgcc ataggccagt cctacttcgc caataccact taatcctgag tcggtattca
     4201 cccggataag tactggatta taggatgaca tcgtttgatc tctttttttt aattcacagt
     4261 caaaaacttc aatagacgta attttcataa tttctccatt tatcaggttc gtgatacaac
     4321 atttgtttgt tggctttttt cttttttcac atcaattttc attaacgcca aaacggctac
     4381 cgcagcgaag caaagtattg cctctacaat aaatattcct gtcgcaccat aatgagtaga
     4441 aacgaatccc agtgacttat taatcaggaa tccgccaaga cttgaacatg agttaataaa
     4501 cgcaatgctg atagccaacc ctgacggcga caataatgca gaaggcagcg cccagtaagg
     4561 tccgtaatag ctgaggatcc caacaccata gaacgttagc cccagcattc tcagcgacat
     4621 tgaggggaca agagcaatca tcagaaaacc acagcctgcc agaaacatgg gtaatgcagc
     4681 atgccatttt cgttcattct ttttatcgga atgccagccc caccagggca tgctgaacat
     4741 agcgaaaata aacggaatac tcatgattaa accaacgtca gtatccgtaa aatcagctga
     4801 aaatcccttc accaaccccg gcaaccagta gtttgccgcc agagcagccg cctgaatcaa
     4861 catgtaggcg aaagaaagct gaagcaaaac tggatttttg attacggaaa gaaaggatga
     4921 gttggtattt ttatttaatg cagctgcggt ttcattgtca gtgcgtaatt tattaactaa
     4981 ggccgatatc tgctgtggcg taagccattt agccttttct ggactgtcag gcagtaaata
     5041 aaatgtcagg atgccaagga atacggtagg gataccttca atagcaaaaa gccagcgcca
     5101 gccttcataa tccggggtat tcaaatgctc gatgatccaa ccagacatcg gtgcagccaa
     5161 taccgatgca acagcaatag ataacatgaa gaaactattg acttttccgc gttcacgagc
     5221 cgggaaccaa catgcaagat aataaaccat gcccgggaaa aagccagctt caaatacccc
     5281 caaaaaaatg cgagccagca aaatatgttg agtatcttta gcaaaaaaaa tcagccctgt
     5341 taccgctccc cagccgataa taatggaact aattcatttt cttgcgccaa gcttttgcaa
     5401 gccaatgcta ctcggaattt gaaagattaa atatgatatg aagaatatag aagaaatatt
     5461 agcgaaatcc tcaggcgtaa taccgagaga ttcattcatg cgtaat
//
LOCUS       DAJVKX010000205         5461 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.205, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000205 DAJVKX010000000
VERSION     DAJVKX010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5461
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.205"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            205..2304
                     /locus_tag="OPY25_004302"
     CDS             205..2304
                     /locus_tag="OPY25_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
                     /protein_id="HCS0929754.1"
                     /translation="MATSKLIQGDTITETTHAANGFDPATSDDKISYTSARVAKPVYN
                     KYKNSTTKPKVFGYYTDWSQYDSRLQGNMSQPGRGCDLTNVSPTAYDKLIFGFVGITG
                     FRKIDKEDRDVVAEAAALCGKVKYEPTFLDPWGDFQSYINLGFETSGWDVDPKTVTQA
                     NAKGMLGALRDMQAKAKAAGHTLALSMSIGGWSMSNGFHETAASDSSRKTFAKGVVKL
                     FKQFPMFSEVDIDWEYPNDEGAGNPFGAEDGANYALLIAELRKQLDSAGLSNVKISIA
                     ASAVTTIFDHAKVKDLLAAGLYGINLMTYDFFGTPWAETLGHHTNRKALEEGGWAVET
                     IVDHLLAEGFSADRINIGYAGYTRNARQVEIESLSPLKGSYNPGSGDTTGSFESGTSE
                     WYDVIYSYLDLENQKGRNGFNVYTDQVADADYLYSPESKLFLSLDTPRTVKAKGEYAA
                     KLGLGGVFTWTIDQDNGVLVNAVREGLGYEIESEVIDMEPFYFEGINVEKDDEQSDSD
                     DAQKVNHAPKAAIELMVVGGSTVQLSGAGSSDEDNDELSFSWGVPSQIDVADKTAEII
                     EVVVPEVSEKTAFQFTLFVRDCYNEPSSQQRFVLTAVPALSQVQPEPEEEEEIIVPVP
                     DEEEETTPAEDDTSADDKTSPYAQWDASTVYGANWGSFEIVSWKGHNYQVKWWSMGNQ
                     PDLNCGVGGAWTDLGAY"
     gene            2396..5392
                     /locus_tag="OPY25_004303"
                     /pseudo
     CDS             2396..5392
                     /locus_tag="OPY25_004303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459024.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
BASE COUNT         1304 a         1373 c         1496 g         1288 t
ORIGIN      
        1 ctatgttctc accagaacgg agtaagcggg cggtgagagg tgttgttttc tcttcgtcag
       61 acggtgttgt taacctcatt tttatgattt ttatatcatc taaaaaggtg atgttttgtg
      121 attagctatt ttttatgcct gtagcgatta tggaccccgc agaacgagct gcgacaattt
      181 tgaaacgtaa aaggaaattt gaaaatggct acaagcaaac tgattcaagg cgatacgatt
      241 actgaaacta cccatgcagc gaatggtttt gaccctgcaa caagcgatga taaaataagc
      301 tatacttccg ctcgtgttgc gaaaccggta tacaataaat ataaaaattc cacgactaag
      361 ccgaaggtat tcggttatta caccgactgg tcacagtatg acagccgtct gcaaggcaat
      421 atgtcccaac cgggccgtgg ttgtgattta accaatgttt caccgacggc ttatgacaaa
      481 ctgatttttg gttttgttgg tatcaccggt ttcagaaaaa ttgataaaga agaccgcgac
      541 gtcgtagcag aagcggcagc gctgtgcggc aaagtgaaat atgagccgac cttcctcgat
      601 ccgtggggcg atttccagtc ttatatcaac ctgggttttg aaaccagcgg ctgggatgtt
      661 gatccgaaaa ccgtgaccca ggctaacgct aaaggtatgc tgggcgcgct gcgtgatatg
      721 caggcaaaag cgaaagctgc aggtcacacg ctggcgctct ccatgagtat cggcggctgg
      781 agcatgagta acgggttcca cgaaaccgcc gcttctgact cttctcgtaa aaccttcgcc
      841 aaaggcgtgg tgaaactgtt caaacagttc ccgatgttca gcgaagtgga tattgactgg
      901 gaatacccga acgatgaagg ggcgggcaac ccgtttggcg cagaagatgg cgctaactac
      961 gcgctgctga ttgccgaact gcgtaaacag ctggattccg cgggtctgag caatgtgaag
     1021 atctctatcg cggcctccgc ggtgaccacg atttttgatc acgctaaagt aaaagatctg
     1081 ttggctgctg gcctatacgg catcaacctg atgacctatg acttcttcgg tacgccgtgg
     1141 gcggaaacgc tgggccacca cactaaccgc aaagcgctgg aagagggcgg ctgggctgtc
     1201 gaaaccatcg ttgatcacct gctggcggaa ggtttctccg ctgaccgtat caacatcggt
     1261 tatgccggct atacccgtaa cgctcgtcag gtagaaattg aatccctgtc gccgctgaaa
     1321 ggttcttaca acccaggttc aggcgatact accggttcct tcgaatccgg caccagcgaa
     1381 tggtatgacg tcatttatag ctacctggat ctggaaaacc agaaaggccg taacggtttc
     1441 aacgtttaca ccgaccaggt cgctgacgct gactacctgt atagcccgga atccaaactg
     1501 tttttatccc tggatacgcc gcgtactgtc aaagcaaaag gcgaatatgc agcgaaactg
     1561 ggcctgggcg gcgtgtttac ctggactatc gatcaggaca acggcgtgct ggttaacgcc
     1621 gtgcgtgaag gtctgggtta tgaaatcgaa tctgaagtta tcgatatgga accgttctac
     1681 ttcgaaggta tcaatgtaga aaaagatgac gagcagagcg atagcgacga cgcgcagaag
     1741 gtcaaccacg cgccgaaagc ggcgattgaa ctgatggtcg taggcggatc gacggtacag
     1801 ctgtctggcg caggttcttc tgatgaagat aacgatgagc tgtcctttag ctggggcgtg
     1861 ccttctcaaa tcgatgtggc agacaaaacg gcagaaatca ttgaggttgt ggtaccggaa
     1921 gttagcgaaa aaacagcctt tcagttcacc ctgtttgtac gcgactgcta caacgaaccg
     1981 tcctctcaac agcgctttgt tctgacggcg gtgcctgcgc tatctcaggt tcaaccggaa
     2041 ccggaagagg aagaagagat tatcgttcct gtaccggacg aggaagaaga gaccacgccg
     2101 gctgaggatg atacgtcagc agatgacaaa acgtcacctt acgcgcagtg ggatgcttct
     2161 accgtttatg gcgcaaactg gggttctttc gaaatcgtta gctggaaagg ccataactat
     2221 caggtgaaat ggtggtctat gggcaaccag cctgacctga actgtggtgt cggcggtgca
     2281 tggaccgatc ttggcgctta ctaatacacg gtattaagcc gatgtattgg gcttcatgat
     2341 tcaagccccg gtttaccggg gcttttctcc accagggaca gaggaagagc agaccatgac
     2401 catttccatc catgccagcg catttgacgt caacagctgg tatcaaaaaa tcaccttaac
     2461 cttcatcaat gagagcggta atccggtcga tatgaaccat gccgcaatat cattcacggc
     2521 ttccgggcac atcgatccat ggggaaatag cggcggtacg ctcaaaggga acccgccgct
     2581 tacgctgaat gatagttcgt atggcacgct ggaaactaac aacatcatca ttaataacag
     2641 cgatgcatta cttcttcagc cgggcgaacg cggaacgctc tctttcagcc tcgcggcgac
     2701 gcaggtgccg gtaaaaatgt ccgccgtcac cttgacgctg gcgtcatcgt catccgaaga
     2761 cgcagagtct gcaaccccat ccgatcagga gacgccagcg atacccgccg cagacgaaca
     2821 acccgccgaa tccgatgtgc cggaaaagga caatgacctt caggaacgcg gccttacgct
     2881 taacgttagc gagttgaatg ccgcaagttg gtatcaacac gtcaccttta cgctgaccaa
     2941 cctctacgcc caggcggtag atctcaatca gcttcaactg aattttacgg ccagcgcgca
     3001 ccccgatccc tacagtccgt ttcagggaac aatgctgggg aatcaggccg tgacgctggc
     3061 cagcgatggg ggatggccca tcgagaagaa taccatcacc attaatcatg acggcgcgct
     3121 gatgctggcg gcaggggata tcgccgaatt acagtgctat ctggccgcca cgcagacgcc
     3181 agttgccatc agcgatttga acgcgacgtt ggcccatgac cctgcccacc agggaaaaat
     3241 ttgcgttcac tttcctgcca tgacgcagac cgtggcgctc aaaccggtga ttgagctact
     3301 gtttcctgcc ggcgaaaccc ggcgctttgt cggtgagtgg ggagaggttc tgacaataag
     3361 cgatcttagc gcaggaacgt atcggcttat cgtaccggta ctggcgaatg atgagatgca
     3421 aatcgcgcca gtcgagtcct cttttaccgt tacgctgcaa tccggagatg ccgccgcgca
     3481 ggtctaggta tcttgtttac cgattgtcca ttatgccagc gcgcgtctga tgattgatgc
     3541 ccctgcgctt ggtaatgcga aattgaccgt tgaaatcgcc gatgctacgc aagcggatga
     3601 gcgtaccgtc acgcttatcg ccaaccaacc gcagttaatc acccggctac tggcggggca
     3661 tcattatacg gtcaatctgc agcctgcgat gattaataac cgctttatat cggcacccat
     3721 acagcttacg ggttttatcc ctgctgcggc gcaggttgcc gaggttgctg tcgcttacca
     3781 acagtcggcg ctcgacacgg cgagcttcgt gacggtagat gccactatac tgggcctgcc
     3841 cgatggcgtc gcgccgcagc gttatctgtt cagcagcggt aaatatcaat actcattaat
     3901 gctggagagc ggcagcgatc ggcagacgct gtcattacgc tttgcgcccg ggctgtatga
     3961 tgttcagacg gacgatattt tcatcgacag tgtgccgtgg cgttgtgaac aggccgggcc
     4021 gctacgcttg ttgcaaaagg tcaaccatgt ggcgctggag tttctgcccg gcgtgacgct
     4081 acaggtaaaa ggttggcctg attaccttgc tcatggcggc gtgacggtta acgcgccaga
     4141 gacggtttct ctttatcgcg atataccgtt tagcgcgttg tttaaatacg acggttttga
     4201 cggcggcggc gatccggtgc cggccgcaga ggttgacgtg aacggggatg tttttctgga
     4261 ttacgcgaca ttaccgatcc ataaaaccgt tgcgctggtg cgccagatcg aaaaagaagc
     4321 cgggcgtagc gtcatgccgg taatggtcat ttataccgcg aatgccagcg gcggcagcgc
     4381 gctggtggat ttacaggatg cgcaaaagct acgtaaccat tttggtaact ttattaccca
     4441 gtgtctggcg gcgcagtcat acaaagatga gacgcatcct gtcccggcca cctttgtgct
     4501 taacccggat tttctgggtg cgctacagca aggaccgtat ggctataccg tagtacggca
     4561 aaaaaacagt gtgccggtga atgcccaact ggcggcggcg atacaagcat taccggcgat
     4621 ggctggcttt atcgcgcctt cgttgccgac gtttagcgac gatctctacg gttatattca
     4681 ggcggtgaac tatcttgttc gtcagtttgc cccggatgtg gcttttggct ggcagacgaa
     4741 tgtctgggcg acaggaacgg cggactgggt gctgcgcgat accgctgatc cggtagctga
     4801 agggcaggcg atcgccggat ttattcatga actgggcgtt tatagcggag aatatgcgcc
     4861 ggactttatt gcgtttgatg aatttgagcg tgactgtttc agtcctgatg cgcttgccca
     4921 ctatggttgg aatgcgacat gctggcttaa ttacctggcg atggtaaaac aggtgacgaa
     4981 agcgctgctg acgcccgcca tgctgtggca aattcctggc ggccatatgc ctacagtaga
     5041 agagggcgtc agcaaaatca gcgctgcgca ctttgcatcc ggcggaacct tttttatggg
     5101 tgacgcccgc attggcagcg atcctgacac gctctctttg cagctactca atacggcctt
     5161 aaatagcgcg acttacggcg tcccgaccgt cggcgacttt ttacgtaaag ataaagggta
     5221 tgactggggc cagatgcagg cgctgaacct accggacttt aacgtctttt cgatcttatg
     5281 gggcggtggt tctactatca gtattacgac aatccattct aacggtgaag acggcggctg
     5341 gctggcggat aaaatggtag agtattatgc tgctccacgc tattttagat aatatcactg
     5401 cttatttgca ttaatctggc ctattagttt gagattcgaa ggcgcgttct ttcgaatctc
     5461 t
//
LOCUS       DAJVKX010000206         5189 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.206, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000206 DAJVKX010000000
VERSION     DAJVKX010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5189
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.206"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            46..1232
                     /locus_tag="OPY25_004304"
                     /pseudo
     CDS             46..1232
                     /locus_tag="OPY25_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141078.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
     gene            1242..1949
                     /locus_tag="OPY25_004305"
     CDS             1242..1949
                     /locus_tag="OPY25_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001786138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HCS0929755.1"
                     /translation="MFLLLPPYFLAGATTKKNKPLIAARIAEEKEKDRLKDLRRDTRR
                     RQWALALADILARRNGLPIKGVELVFKLDDDKHRYLAQQVKKELGLSENLNGAALRHK
                     VEDILRRWPAGIGSSPSTFYHHLAAQGQVRDALAFDCMRTAFLTRCIAGLGWCDENEA
                     WLVLLLNAQRAQDCFDSWEDYATAYVRARRVWLTLRDTPIALAGRDLQEATHYLQDPV
                     SRWRQLPWNEFKIFEPI"
     gene            1960..4071
                     /locus_tag="OPY25_004306"
                     /pseudo
     CDS             1960..4071
                     /locus_tag="OPY25_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461079.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4034 domain-containing protein"
     gene            4076..4795
                     /locus_tag="OPY25_004307"
     CDS             4076..4795
                     /locus_tag="OPY25_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCS0929756.1"
                     /translation="MIIQRKSLFLCALLLLFATARAEITEQQIEADCAKIPVLASQGE
                     QLYKTQKYAKALDAFEQLAAWSESCALDDNAIATAYNNVALTWIREGEWRKARAWLML
                     RPNDSKSIYNLKLIKDKLSVLPPPVSTAGEYWRYAGRASWNVLSVKALPTPSRYQVNF
                     QGYWFGLMGIYFGPNIGEFYAEITLENDKAIVALREGDDIHCDISLAFSSETIDASTD
                     TFVDCGFGANVRADGHYLRVE"
BASE COUNT         1305 a         1349 c         1299 g         1236 t
ORIGIN      
        1 aaaaatacat aaacataatg ccagcttaat tacacatgga tttttatgac agaaacgtca
       61 tctcaccgct ataaaccacg caatataata aatgcgccaa atgtaaaatc atctattttt
      121 tcccggagcc aacaacgcgg cgatagcgaa aatatccagc gctggttaag caatcatttt
      181 tatcgttgga tcattggtga ctttcctcac gtttaccctg tgcgctccgt cgctgattat
      241 gccgtttatt ttagccctga tgcagaaatc cccgcctggg tggcgatgag cgcttttact
      301 accttaacgt tcagcacccg caacttgtgg caatggaaag agatttagtg gaatttcttt
      361 cgcgtcagga aggaacgcgg ctggaaacta aactacagcg catcaactgc tttaccgtgc
      421 tggcaatgcg cgaagcggag catcaaaaaa tgcagcacct gcgtgaacaa ggttggtatc
      481 cctccaacag cgaggcgcta aaaccggtga tggcggtgaa taacggtgtg ctggttgagc
      541 ttgatgcaac aaaccccggc ctgcgcagtg agatggcgta tgaatcctgg catatgcaac
      601 actgcgtcgg agattttgat aataaaggcg cgctttccgg cggctacggc gattactacg
      661 cccggcaaat tgaacaacag aaacttcgcc tgttcagcct gcgcgacggc aataatattc
      721 cccacgtcac aataagcctg gtggttggta ataacggcct gagcattgat cagattaaag
      781 gtaagcaaaa tcgccatcct attaagaaat atgctaacga tgttttatct ctgttacgcc
      841 atctgcaacc acttcctgag cgccacgctg attgcgaagg gatgggaata gtttatgaat
      901 cgacgccgga atattcaggt tggaaattta ttactcatat tcatgacctc aattttctgc
      961 tcaatgtgct gcatgacaat tttcatttaa tggaacactt ccccactccc ccggtagctt
     1021 tacagtggct gctgctgcac agcgccccgg aggcgctgcg ctaccttcag gttgttgatc
     1081 ctaacgtggc gacggctgcg gaaatgctgt ttccacggca tgaatggcac cctacgcttg
     1141 ccgggaaaaa caccagtagt gaacctttcg aaattgaaag cctgacgcta caaaccacgc
     1201 gttacctccc tgtcatcaag gaggtgcaat aatgttctgg attgttctta ttattgccgc
     1261 cctatttttt agctggcgca actacaaaaa aaaacaaacc gctgattgcg gcccgtatcg
     1321 ccgaggagaa agaaaaagat cgtctgaagg atctgcgtcg cgatacccga cggcggcaat
     1381 gggcgctggc gctagctgat atcctcgccc ggcgcaacgg gctaccgatc aaaggcgttg
     1441 agctggtctt caaacttgac gatgacaaac accgctatct ggcacagcag gtaaaaaaag
     1501 agctgggctt gagcgaaaac ctcaacggcg cggcgttacg ccacaaggtc gaggatatct
     1561 tacgccgctg gcctgcgggc atcggcagct cgccgagcac gttttatcat catctggcgg
     1621 cccagggcca ggtccgcgac gcgctggctt tcgactgcat gcgaaccgcc tttctgaccc
     1681 gctgtatcgc cgggctcggc tggtgtgacg aaaacgaggc ctggctggtg ttattactta
     1741 acgcccagcg cgctcaggac tgttttgatt cctgggagga ttacgccacc gcctacgttc
     1801 gcgcccgccg ggtatggctc acgctacgtg acacgccaat agcgcttgcc ggacgggatt
     1861 tacaggaagc cacccattat ctgcaagacc ctgtcagccg ctggcgacaa ctgccgtgga
     1921 atgaattcaa aattttcgag ccgatttaaa ggactattta tggaacagga tgatcgtctg
     1981 ctcaacgcta tgtttgagat gtgcaaccac aaaaatcccc tcaatgacgg gcaacgagag
     2041 tggcatatcg ccgatattcc cggcctgctg cgcgaagaac gctatgacga actggacgaa
     2101 cgctacaacc aggcgctgac ggagagcttt accagccgcg aagcggaaaa gcgctatttc
     2161 ttcgcctgga atcaaatgga caaccctttt tacgatatgg acacgctggt tgaggctggg
     2221 ccgcaaggat tagcgctgat caaaaactgg cagcgcgctc gtccccgctc cactcacgcc
     2281 tggcttgccg aggcgcaata ctggaatcac cgtgcgtggc tttaccgcag ctatggctgg
     2341 gcgagagaaa ccacccgagc gatgtggatc tgcgccgccg cctgcaacga acggatggtc
     2401 atcgccgcgc tcaatgctat cgactgtgaa ccgcgccagt ggatggcggc ggccctgacc
     2461 agcaccaact caaaagtctt cggccagccc gactggctgg ttgagttcct cgagggcgcg
     2521 gatgttgccg ggcagccatt aatggaagat ctggctgaat atcatcgcca ttcaccgcag
     2581 gaggtggatg cgctgatggc ccattccggg ctgtcgtttg ccgacgcggt ttgcccaaat
     2641 ttgccgcgcc cgtccgtgct gccggagtgc aatgacgatg ccgggcaaaa atactggctc
     2701 gccgtctgcc tggctatttt cccgacggca ttttacgtgc tggatgaata tatcccgttt
     2761 cgtatgccgc gctggggagg gtctcacgag gaaatccgcg aatttctgga atcaagcgta
     2821 tgcgatcacc tttctgccgc agaacgtgaa catctggagc tattgatctg gtgggacgat
     2881 caccgcgatc tgcgcatcaa agaggttgac tccccggcag aacaggaacg cattatcgcc
     2941 aaagccgaag agattagcct gcgagcgcat atccaggaat ctcgccacaa cacgctgaag
     3001 tggctgcggg tctgctatag cgatctggac gataatgacg cgctctggcg aacccttcag
     3061 cgttcgatcg tggaaaaagt taagttcaac aattacttct ttgatgacac gataaagttc
     3121 gccctgcgcg attttcctga cacctggtgg atgtataatt ttctctgtca gaatgcgcag
     3181 caaacggaat tcgcagtgcc gaaaatccgt cgtggctact ttcagtacgc cgggttattg
     3241 ggtttcgaaa aggatgaggc gcaaggcctc gcctagctcg atagcgtcgc cgacattcaa
     3301 tataaccata actggcgggc ggcgattaaa aatttcgact ggttcgggct cccggaacat
     3361 tttgtgccgc tggcagagct gggcgcacaa agaaatatac ccgccgcgct aaacctgctg
     3421 ggccttgaac acaataataa agagaacaac ggcctactac cttacgatcc tgccatcgcg
     3481 ttagggtatt ttcagcgcgc ggcggagatt ttgcaccggc ggttagcgct gcgcgagagc
     3541 accccgtaca aattaataga taacggaggc tataccgact atgaaaatga cctgcaaaat
     3601 attcatttca gcatcggcat ctgcaaccag cgtctgagta aacaagaact tgataccgaa
     3661 aaacgttccg cttatgaaaa agaactgctc gataatctct ggctggcgca tcagttcggg
     3721 cataaagagg cctggggctt gttcctgctg aatatttttg aagtgaagga tattacgctg
     3781 gcgcataagc atctggaact ggtgcaacaa gaggccaaca aaggcacgct acacgctatg
     3841 gtgaccctat cgcgcctgca cggtaataaa cacgatcgaa cgctgtttaa tatgaagcta
     3901 agcgcacgct gggcacattt tgccttcacg ctttacccgg ataatgaaat cgttatggat
     3961 tgcctggacc acctgcattt cgattctttc tggaaacgct ttcgtttcgc ctggtatacc
     4021 gtccgtatcc cgaattcaga gctgccggga caggtcaact caatggtgta atggagtgat
     4081 aatacaaaga aaatctctat ttctttgcgc cctgcttcta ctcttcgcca ccgccagggc
     4141 tgaaattacg gagcagcaga tcgaggccga ctgcgcaaaa attccagttt tggccagcca
     4201 gggcgaacag ctttacaaga cccaaaagta tgccaaagca ctcgacgctt ttgaacagct
     4261 ggccgcatgg agcgaaagct gcgcccttga cgacaacgcc atcgcgacgg cctacaacaa
     4321 cgtggcgcta acctggatac gcgaaggcga gtggcgtaaa gcccgcgcct ggctgatgct
     4381 aaggccgaat gatagcaagt cgatctacaa cctgaaactg atcaaagata agctatcggt
     4441 cctgccgcca ccggtttcca cggcgggtga atactggcgc tatgccgggc gcgcctcctg
     4501 gaacgtgctt agcgtgaagg cattacccac tccatcgcgc tatcaggtta attttcaggg
     4561 ttactggttc ggtttaatgg ggatctactt cggccccaat atcggcgagt tctacgcaga
     4621 gataacgctg gaaaacgata aagccatcgt ggcgcttcgg gaaggcgatg atattcactg
     4681 tgacatttcg ctggcttttt cttctgaaac cattgatgcc agcactgata cgtttgtgga
     4741 ctgcggtttt ggcgcaaatg tccgcgccga cgggcactat ctgcgcgttg aataaatctg
     4801 gcgcggaaac tgaaatttta tgattaacct gagatcagtt gaaattaaca atctatttat
     4861 aatttccata acgttcctca ttctttcctg ctatccatat tatcttaaca cctccattac
     4921 aattattaat gtcgtaagca tggtatattt aacgctcgct tcttttttca ccctgtgata
     4981 ctgcatttct ggatatcaat ttgaatcgac cattttccat ttgatattgt tcctttatat
     5041 aaatctgagg cgcctgatct ttaaacttta tagttacaag atgaccatct ttgctgtcct
     5101 cataccacct gtatataaca taactatcaa tgcttattgt gtaatcctgg cggatgacaa
     5161 aatcagaaaa acgcacgatg tcttcataa
//
LOCUS       DAJVKX010000207         5143 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.207, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000207 DAJVKX010000000
VERSION     DAJVKX010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5143
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.207"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(122..1162)
                     /gene="galM"
                     /locus_tag="OPY25_004308"
     CDS             complement(122..1162)
                     /gene="galM"
                     /locus_tag="OPY25_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HCS0929757.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNSAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPEHYPEQTSFLGASIGRYANRIANSRYTFAGETVQLSPSQGENQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALTSDDGDQGFPGHLCATAQYRLTDDNRISITY
                     RATVDKPCPVNLTNHVYFNLDGDRTDVRQHKLQILADEYLPVDESGIPRQGLKSVANT
                     SFDFRMPKVIASEFLADDDQRKVKSYDHAFLLQTQGDGKKPAARLWSQDGKLQMMVYT
                     TAPALQFYSGNYLAGTPSRGPEPYADWQGLALESELLPDSPNHPEWPQPDCILRPGEE
                     YASLTEYQFIPF"
     gene            complement(1156..2304)
                     /gene="galK"
                     /locus_tag="OPY25_004309"
     CDS             complement(1156..2304)
                     /gene="galK"
                     /locus_tag="OPY25_004309"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCS0929758.1"
                     /translation="MNLKEKTRALFAEIFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRTVRVIAADYDNQVDEFSLDAPIVTHDSQQWSNYVRGVVKH
                     LQQRNNAFGGVDMVISGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRTLGAKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVSLEAFNAVASELDPVVAKRVRHVLSENARTV
                     EAASALEKGDLQRMGQLMAESHASMRDDFEITVPQIDTLVDIVKATIGDQGGVRMTGG
                     GFGGCVVALIPEDLVPAVQQAVAQQYEAKTGIKETFYVCKPSQGAGQC"
     gene            complement(2307..3353)
                     /gene="galT"
                     /locus_tag="OPY25_004310"
     CDS             complement(2307..3353)
                     /gene="galT"
                     /locus_tag="OPY25_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HCS0929759.1"
                     /translation="MTPFNPIDHPHRRYNPLTGQWVLVSPHRAKRPWQGAQETPSQQM
                     LPAHDPDCFLCAGNTRVTGDKNPDYKGTYVFTNDFAALMADTPDAPDSHDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSLPALTEIVRTWQTQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQVWANSFLPNEAEREDRLQKAYFAEQRPPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKTHVLRITDLSDEQRDSLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENAHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            complement(3364..4380)
                     /gene="galE"
                     /locus_tag="OPY25_004311"
     CDS             complement(3364..4380)
                     /gene="galE"
                     /locus_tag="OPY25_004311"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCS0929760.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVVILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALITEILHDHAIDTVIHFAGLKAVGESVAKPLEYYDNNVN
                     GTLRLVSAMRAANVKNLIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPEWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRESLAVF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLADKSGVHIYNLGAGVGSSVLDVVNAF
                     SKACGKPINYHFAPRRDGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYSD"
     gene            complement(4603..>5143)
                     /locus_tag="OPY25_004312"
     CDS             complement(4603..>5143)
                     /locus_tag="OPY25_004312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2167 domain-containing protein"
                     /protein_id="HCS0929761.1"
                     /translation="KNWDADELMDNLRKGTKEANKDRIAKGIEPIEIIGWIEKPTYDA
                     TNHRLIWSAAIQDIGTNEPLNEQGVNYNTYLLGREGYFSLNLVTDRGSVDHEIPLAKR
                     ILSSVKFNAGQRYADFNESTDKIAEYELAALIGGIAAKKVGLLAMLGIALLKFWKVTA
                     IGVVAVGALARKLLSRKKD"
BASE COUNT         1092 a         1384 c         1446 g         1221 t
ORIGIN      
        1 gcagtgtaag gttcttgtga actcagagtt gcgattttgt ctttaagtgg tggaggtttg
       61 agcagggcaa tggcgcgtag gcccgataag cttgcgtcat cgggcatgta gcggcatatc
      121 gttagaacgg aataaactga tactcggtca ggctggcgta ctcctcgcca gggcgaagga
      181 tacagtcagg ctgcggccat tcaggatgat tcgggctgtc cggcagcagt tcgctttcca
      241 gcgccagccc ttgccagtcg gcataaggtt ccggtccgcg ggaaggtgta cccgccagat
      301 aattgccgga ataaaactgt agcgccgggg cggtggtgta aaccatcatt tgtagctttc
      361 catcctgtga ccacagacgg gccgccggct ttttgccatc accctgcgtc tgtagcagga
      421 aagcatgatc gtagctttta accttgcgct gatcgtcatc ggcgagaaac tcgctggcaa
      481 tgacttttgg catccggaag tcaaacgagg tattggctac cgattttagc ccctggcgtg
      541 gaataccgga ttcatctacc ggcagatact catccgccag aatttgcagc ttatgttggc
      601 gcacgtcggt ccgatcgccg tccagattaa aatagacgtg gttggtcaaa ttcaccggac
      661 agggtttatc gaccgtcgcc cggtaggtga tggagattct attgtcatcg gtcagacgat
      721 attgcgccgt ggcgcaaaga tggccaggaa agccctggtc gccgtcatca gaggtgagcg
      781 cgaataatac ctggcgatcg ttttggttca caatttgcca gcggcgcttg tcaaagcctt
      841 ccggtccgcc gtgtagctgg ttctcgccct ggcttgggct taactgtacg gtttcgccgg
      901 caaacgtata gcggctattg gcgatacggt tcgcgtaacg gccaatagag gcgccgagga
      961 atgacgtctg ttcagggtag tgttccgggc tggcgcagcc cagcaatgct tcccgaacgc
     1021 tgccgtcaga cagcggaata cgggcggaaa gaagagtggc tccccagtcc atcagcgtta
     1081 ccaccatccc tgcgctgttg cgcagggtta gcaggcggta cggttgacca tcgggggcca
     1141 gtgcgggcgt ttcatttagc actgtcctgc tccttgtgac ggtttgcata cataaaaggt
     1201 ttctttgatt ccggttttcg cttcgtactg ttgcgcaacg gcctgctgca cagcgggaac
     1261 cagatcttcc gggatcagcg cgacaacaca gccgccaaag ccgccgccgg tcatgcgcac
     1321 gccgccttga tcgccgatgg tcgctttgac aatgtctacc agcgtgtcta tctgcgggac
     1381 ggtaatttcg aaatcatcgc gcattgaggc atgggactcc gccatcagtt ggcccatacg
     1441 ttgcaaatca cctttctcca gcgcgcttgc cgcttcaacg gtgcgcgcat tttcgctcaa
     1501 tacatggcga acgcgttttg cgactaccgg gtccagttcg ctggcgacgg cattgaacgc
     1561 ctcaaggctg acatcgcgca gggccggctg ctggaagaaa cgggcgccgg tttcgcactg
     1621 ttcacggcgg gtattatact cgctgcccac cagagtgcgc ttaaagttac tgttgatgat
     1681 caccacggcg acgcctttcg gcatagaaac cgctttggcg ccgagcgtac ggcaatcaat
     1741 cagcaacgca tgatcttttt tgccgagcgc agagatgagc tgatccataa tgccgcagtt
     1801 acagccgaca aactggttct cggcctcttg tccgttgagc gcaatttgcg cgccgtccag
     1861 cggcaggtga taaagctgct ggaagacggt gcccaccgcc acttccagcg aagcggagga
     1921 gcttaacccg gcgccctgcg gcacattgcc gctgatgacc atatccacgc cgccaaacgc
     1981 gttgttacgc tgttgcaggt gtttcactac gccgcgcaca tagttagacc actgctggct
     2041 atcgtgggtc acgatcggcg catccagtga aaattcgtcc acctgattgt cgtaatcggc
     2101 ggcaatcacc cgtacggtac gatcgtcgcg cggcgcacag ctaattacgg tctggtaatc
     2161 gatagcgcag ggcagaacaa aaccatcatt gtaatcagtg tgctcgccga tcagattgac
     2221 gcggcctggc gcctgaatcg tgtgggtagc agggtagccg aaaatttcag caaacagcgc
     2281 gcgcgttttc tctttcagat tcatttttat actccggatt cgcgaaaatg gatgtcgctg
     2341 accgcgcgca ggcgttcagc cgcttgttct gcggttaaat cacgctgggt ttccgccagc
     2401 atttcatagc cgaccataaa tttacggacg gtcgcagagc gcagcagcgg cggataaaag
     2461 tgcgcgtgca actgccagtg tgcgttttct tcaccgttaa acggcgcgcc gtgccagccc
     2521 attgagtagg ggaaggaaca ctgaaacagg ttgtcataac gactggtcag ctttttcaac
     2581 gccagcgcca gagagtcgcg ctgctcgtcg cttaaatcgg taatgcgcag gacatgcgtt
     2641 ttgggtaaca gtagcgtttc gaacggccac gccgcccagt aaggcaccac cgccagccag
     2701 tgttcggttt cgaccacggt gcggctgccg tccgccagtt ctcgctggac ataatctacc
     2761 agcattggcg gacgctgttc ggcgaaatag gctttttgta aacgatcttc gcgttcggcc
     2821 tcattcggca ggaagctgtt ggcccagacc tgtccatgcg gatgcgggtt cgaacagccc
     2881 atcgccgcgc ctttattttc aaagacctgc acccacggat aggttttgcc taactcggcg
     2941 gtctgcgttt gccaggttct gacgatttcc gtcagcgcgg gcaggctcaa ctccggcagc
     3001 gttttactgt gatcgggaga aaagcagatc acgcggctgg tgccgcgcgc gctctgacag
     3061 cgcatcagcg gatcgtggct gtccggcgca tccggcgtat cggccatcag cgccgcgaaa
     3121 tcgttagtaa agacgtaagt ccctttgtaa tcgggatttt tatcgccggt gacacgcgta
     3181 ttgcccgcac acaagaagca gtccggatcg tgggccggca gcatttgctg agacggcgtt
     3241 tcctgcgccc cctgccaggg gcgttttgcg cgatgcggcg aaaccagaac ccactggccg
     3301 gtaagcgggt tataacggcg atgcggatga tcgatgggat taaatggggt cataacaacg
     3361 tccttaatct gagtatccct gcggatggcg tgactgccag tgccaagtgt cctgcgccat
     3421 ttcgtcaagc gtgcgggtga cgcgccagtt cagctcgcga tcggctttgc tggcatccgc
     3481 ccaatacgcc gggagatcgc cgtcgcgacg cggcgcgaag tggtaattaa tgggtttacc
     3541 gcaggcttta ctaaaggcgt tgaccacatc caggacgcta ctgccgacac ccgcgccgag
     3601 gttataaata tgtacgccgg atttgtccgc cagtttttcc atcgccacga cgtgcccgtc
     3661 ggctaagtcc ataacgtgaa tgtaatcgcg tacgccggtg ccatcctcgg tcgggtaatc
     3721 gttgccgaaa acggcgagcg attcgcgacg acccacggcg acctgggcga tatagggcat
     3781 caggttattc ggaatacctt gcggatcttc tcccatgtcg cccgacgggt gcgcgccgac
     3841 cggattgaaa taacgcagca gcgcaatact ccactccggc tgggcttttt gcagatcggt
     3901 gaggatctgt tctaccatca atttactttt gccgtagggg ctttgcggcg tgccggtagg
     3961 aaaactttcg acgtaaggaa ttttgggctg atcgccataa acggtggcag aggagctaaa
     4021 aataaggttt ttaacgttgg ccgcacgcat ggcgctgacc aaccgcagcg taccgttgac
     4081 gttgttgtca tagtactcca gcggcttggc gaccgattcg ccgacggctt tcaggccggc
     4141 aaagtgaatc acggtatcaa tcgcgtgatc gtgcagaatt tcggttataa gcgcttcgtt
     4201 gcgaatatcg ccttcgacaa aggtcgggtg cttaccgccc agacgttcaa taacgggcag
     4261 cacgctgcgc ttgctgttgc agaggttatc gaggatgacg acgtcatgac cattttgcag
     4321 caattgtacg caggtatgac ttccaatgta accgctacca cctgtaacca atactctcat
     4381 aattcgctcc gttaagccta tggtatggaa taaccatagc ataacaaaga tgcgaaaagt
     4441 gtgacatgta ataaattagt ggaatcgttt acacgctggt gattttacgc atttatatca
     4501 attaaatgat tacaaatcat ctgacttgag aatgcttctg ctttttatcc gaaaaaaagg
     4561 cgcgttacgc gcctgggaat gaaacggacg gggcaggagc tgtcagtctt ttttacgcga
     4621 gagtagcttc ctggcgagcg ccccgacagc gacgacgccg atggcggtca ctttccagaa
     4681 tttaagtaac gcgataccga gcatagcaag cagtcctact ttcttggccg cgataccgcc
     4741 aatcagcgcg gcgagctcat actccgctat tttgtccgtt gattcgttga agtcagcgta
     4801 gcgttgtcca gcgttgaact tgacggaact gagaattctt ttcgccagag ggatttcgtg
     4861 gtcaacagaa cctctgtcgg tcaccagatt taaagaaaaa taaccttcac gtcccagcag
     4921 ataggtgttg tagttcacgc cttgttcatt cagtggttcg ttggtgccga tatcctggat
     4981 ggcggcggac cagatcagac gatgattggt tgcatcgtag gtaggcttct cgatccagcc
     5041 aataatttct atcggctcaa tgccttttgc aatacgatct ttattcgctt cttttgtgcc
     5101 tttgcgcagg ttatccatta attcatcggc atcccagttt ttt
//
LOCUS       DAJVKX010000208         4887 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.208, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000208 DAJVKX010000000
VERSION     DAJVKX010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4887
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.208"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(58..1062)
                     /gene="cra"
                     /locus_tag="OPY25_004313"
     CDS             complement(58..1062)
                     /gene="cra"
                     /locus_tag="OPY25_004313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HCS0929762.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVNFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDH
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIRRNLYRRGILSRS
                     "
     gene            complement(1346..1837)
                     /gene="ilvN"
                     /locus_tag="OPY25_004314"
     CDS             complement(1346..1837)
                     /gene="ilvN"
                     /locus_tag="OPY25_004314"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HCS0929763.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGREEVK
                     RNTEIFRGQIIDVTPTLYTVQLAGTSDKLDAFLASLRDVAKIVEVARSGVVGLSRGDK
                     VMR"
     gene            complement(1840..3564)
                     /gene="ilvI"
                     /locus_tag="OPY25_004315"
     CDS             complement(1840..3564)
                     /gene="ilvI"
                     /locus_tag="OPY25_004315"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HCS0929764.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGDVGVVLVTSGPGATNAITGIATAYMDSIPLVILSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPLVLKKAFWLAASGRPGPVVVD
                     LPKDILNPAKKMPYVWPETVSMRSYNPTTSGHKGQIKRALQTLASAKKPVVYVGGGAI
                     SAACYAPLRHIIETFNLPVVSSLMGLGAFPATHRQSLGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVNADIPVVGDARLVLEQMLEL
                     LAQDAPSQPQDDIRDWWQQIESWRARQCLKYDAESESIKPQAVIETLWRLTKGDVYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPKEMVVCVTGDGS
                     IQMNIQELSTALQYELPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGLQINRPDELESKLSEALEHVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            complement(3886..4830)
                     /gene="leuO"
                     /locus_tag="OPY25_004316"
     CDS             complement(3886..4830)
                     /gene="leuO"
                     /locus_tag="OPY25_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HCS0929765.1"
                     /translation="MPEVKTEKPHLLDMGKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     TLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPTSSERVFNLCVCSPLDNILTSQIYNRVEKIAPNIHVVFKASLNQNTEHQLRYQ
                     ETEFVISYEEFRRPEFTSVPLFKDEMVLVASRKHPRISGPLLEGDVYNEQHAVVSLDR
                     YASFSRPWYDTPDKQSSVAYQGMALISVLNVVSQTHLVAIAPRWLAEEFAESLELQIL
                     PLPLKLNSRTCYLSWHEAAGRDKGHQWMEDLLVSVCKR"
BASE COUNT         1190 a         1392 c         1157 g         1148 t
ORIGIN      
        1 tactgatacg catttgtttg acggcggcag aagagagagt cttttaccgc cggtccttta
       61 gctacggctc agaatgccgc gacgatacag gtttcgccga atacgcgtta agccgggttt
      121 cggtttacgc ggttcatcaa gacttgccag cacaatctcc agcacgcgtt ccgcgacatc
      181 acgatgacgc tgcgccaccg ccagtaccgg gcattgcaga aaatccagca gctcatgatc
      241 gccaaaggtc gcaatcgcta aatccgaagg cagttttcca tcgcgccgca gcgtaacgtc
      301 catcacgccc tgtaatagcg cgaatgatgt cgtaaagagc gcctgcggca taggatgcgt
      361 ttccagccat ttctcaaaca gctgcgcggc ggcttcgcgc tcatagctgt tggcatataa
      421 gaaattcacc tcccgcggat cgtctttcca tgcggtgcgg aacccctgct cgcgcaggaa
      481 actgacggac aactccggca gcgcgcccaa ataaagcacc gtttccgccg ggaatttacg
      541 cagctcttcc gccaacatct cggcatcatc ctgatcggcg ccgaccacgc tggtgaaatg
      601 ttcgcgatcc agcgcgcggt cgagcgcgac gatggggaac ggatcgttgg cccagcgctg
      661 atagaaggga tgctccggcg gtaacgaagt tgaaacaatg attgcatcca cctggcgttg
      721 caaaaggtgc tcaatgcagc gcatttcgtt atccggctga tcttcagaac aggcgatcag
      781 cagttggtag ccacgctggc gtgcctggcg ctcaagatag tttgcgatac gggtgtagct
      841 cgtgttttca aggtccggga tcaccagacc aatggaacgt gtgcgtccag cacgcagccc
      901 ggcagccaca gcgttaggat ggtaattgtg ctcacgcact accgccatga ctttttctac
      961 ggttttgtcg ctcacgcggt attgctttgc tttaccgttt ataacgtagc ttgcagttgt
     1021 gcgcgagaca ccggccagcc gagcgatttc atccagtttc acaattgccc cttgtgtaaa
     1081 ttgtacaaac cataaccttt atgtcggcat gggttaaaat cgttaacatc taagcgcagt
     1141 ttgatcactc cggcaaccgc ttttattccg ggttaccacg gatttcgcaa aaaaaagccc
     1201 aaccgatgat attgggttgg gcgataattc ctgttggctg atatccggca aacctgcctg
     1261 atggcgctac gcttatcgga cctgggccag atatcagcct gtagaccgga taaaacgcaa
     1321 gcgcgtcgtc atccggcgaa tctgctcagc gcataacctt atcgccgcgc gaaagcccga
     1381 cgacgcctga acgcgccact tcaacaattt tcgccacatc gcgcagcgag gccagaaaag
     1441 catccagttt atcgctggtg cccgccagtt gaacggtata caacgttggc gtaacgtcaa
     1501 taatctgacc acggaaaatt tccgtattac gcttcacctc ttcccgtccg tagccgctgg
     1561 cctggatttt caccagcatg atttcccgct caacgtgcgc tccctgtccc agctcgctga
     1621 cgcgcagcac atcaaccagc ttgtgcagtt gcttttcaat ttgctcaagc actttttcat
     1681 cgcctaccgt ctggatagtc atgcgcgaca acgtcggatc gtctgtcggc gcaacggtca
     1741 ggctttcaat attatatccg cgttgcgaaa agaggccgat aacccgcgat aacgccccag
     1801 attcgttttc cagtaatacc gataaaatcc ggcgcatcat caggtcctct ccgttttgct
     1861 taaccacatt tcgtccatcc cgcccccgcg aatctgcatc ggatagacat gctcgctgcc
     1921 atcaacggtg acatcgacga acaccagtcg gttattacgc acatgctcaa gggcttcgct
     1981 gagtttactt tccagctcat ccggacggtt aatctgcagc ccgacatggc catatgcttc
     2041 cgccaggcgc acaaaatccg gtaacgactg catataagac tgagaatggc gaccggaata
     2101 gatcatatcc tgccactgtt tcaccatccc caggtaacgg ttgttcaggt tcagaaccag
     2161 taccggcagt tcatactgta aggctgtcga cagctcctga atgttcatct gtatactgcc
     2221 atcgccggtc acgcagacca ccatttcttt cggcagggcc attttaacgc ccagtgcagc
     2281 cggtaggcca aaccccatcg tgccgagccc gccagagtta atccagcgac gtggcttatc
     2341 gaacgggtag tagagggcgg caaacatctg gtgttgtcct acatcggacg tcacgtacac
     2401 atcacccttc gtcagacgcc agagagtttc aatcaccgcc tggggtttaa tgctttcgct
     2461 ttccgcgtca tatttcaggc actgacgggc gcgccagctc tctatctgct gccaccagtc
     2521 gcgaatatca tcctgcggct gagacggcgc atcctgcgcc agtagctcca gcatttgttc
     2581 cagtaccagg cgtgcatcgc ccaccaccgg gatatcagcg ttaaccgttt tggatatgga
     2641 cgtcgggtca atgtcgatgt gtaataccgt cgcgttcgga caatatttag cgagattatt
     2701 cgtcgtgcgg tcgtcaaatc gtacgccaac agcgaaaatc acgtcggcgt tatgcatggt
     2761 catattggct tcataagtgc catgcattcc cagcattcct aacgactggc gatgagtagc
     2821 aggaaacgcg cccagtccca ttaatgaaga gaccaccggc aggttaaagg tttcaatgat
     2881 gtggcgcagc ggcgcatagc aggccgcgct tatcgcccct cccccaacat agaccaccgg
     2941 cttttttgcc gacgccagcg tttgcaaggc acgcttaatt tgtcctttat gtcctgatgt
     3001 tgtgggattg taagagcgca tactgaccgt ttccggccag acatacggca tttttttcgc
     3061 cggattcaaa atatctttcg gcagatccac gaccaccggc ccaggacgtc cgcttgccgc
     3121 cagccagaag gcctttttaa gcaccagggg aatatcttcc gtctgtttga ccaggaagct
     3181 atgtttgacc accggtcggg aaatccccac catgtcgcac tcctgaaagg catcatagcc
     3241 aatcaatgag gtggcgacct ggccggaaag aatcaccagc ggaatggaat ccatataggc
     3301 cgtagcaatc cctgtaatcg cattggtcgc tcccggtccg gaagtcacca gcaccacgcc
     3361 aacgtcgcca gtggctcgcg ccaggccatc cgccatatgc accgcggcct gctcatgacg
     3421 caccagcaca tgatcgatcc ctccaacggt atgtagcgca tcataaatat caagcactgc
     3481 gcctccagga tagccgaaca cctgctttac gccttgatcg ataagcgatc ggacgaccat
     3541 ctcggctcca gacaacatct ccacggcttg cctccacttt atacctgtca tcacggtttg
     3601 acggacacct taaccgctcg ctatcacgcc tggcaattgg gtggaatgac gtaaagatgg
     3661 ggaaggttag aataatcagg aggcaagaag agaagaaatg gagaaatact ccgtctgaat
     3721 cacaccaggt aataaataat cgcttataaa tgcagactta cagcaattca tctatttttc
     3781 acagcgacga aaagaatcgc tcaccgttaa ttcagcataa aatttttgac atacgctaaa
     3841 aagcagaata aaccagaatt tgtttctgat ttattctgcc cggttttatc gcttacaaac
     3901 agagactaat aaatcttcca tccattgatg ccctttatca cgcccagccg cttcatgcca
     3961 ggaaaggtag catgtccggc tattcagttt taaaggcaac ggcagtattt gcagctccag
     4021 cgactccgca aactcttccg ccagccagcg cggggcaata gcgaccaaat gcgtctgcga
     4081 aaccacgttc agaacgctga taagcgccat gccctgataa gccacgctcg actgtttatc
     4141 cggcgtgtca taccacggcc gactaaatga cgcataacga tcgagagaaa caaccgcatg
     4201 ttgttcatta taaacatcgc cttccagtag cgggccgcta atacgcgggt gttttcggct
     4261 ggcgactaaa accatttcat ctttaaatag cggtacgctg gtaaactcag gacgacggaa
     4321 ttcttcataa ctaataacga actcggtttc ctgatagcgt aactgatgct cagtattctg
     4381 attcaacgac gctttaaaaa cgacatgaat atttggcgca attttttcta cacgattata
     4441 aatctgtgac gtcaggatat tatccagcgg actgcacacg caaagattga atacacgttc
     4501 gctgctggtc ggctcaaacc ccgatcccgg caattcattt tgcaccaatt gcaacgcctg
     4561 acggactgaa ccaaataact gaaatgcacg ggcagtcggc tgaattcctc gtccatatcg
     4621 aacaaaaagt tcgtcattaa acataacctt cagacgcgct acggcgttac tgaccgcagg
     4681 ctgcgacatt cccagcgtgt gggcggcgcg cgtaatattc tgctcttgca ttaccgcatc
     4741 gaacacggtc aataggttca aatcaaccat gcgaagctgt ggtttgccca tatctaaaag
     4801 atgcggcttt tcggttttga cctctggcat atttaactcc actgtcacgc ttaactccct
     4861 ttttctggct gaaggcagaa ataattc
//
LOCUS       DAJVKX010000209         4838 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.209, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000209 DAJVKX010000000
VERSION     DAJVKX010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4838
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.209"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(420..2852)
                     /gene="metL"
                     /locus_tag="OPY25_004317"
     CDS             complement(420..2852)
                     /gene="metL"
                     /locus_tag="OPY25_004317"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HCS0929766.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLISWLKLSQTDRLSAHQVLQTLRRYQCDLISGLLPADAADDLTSAF
                     ISDLERLAALLDGGVTDAVYAEIVGHGEIWSARLMSAVLNQQGLDAAWLDARAFLRAE
                     RAAQPQVDEGLSYPLLQQLLAQHPGKRLVVTGFISRNHDGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSDIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDICLIEFQVPASQDFRLAH
                     KELDQILKRAQARPLAVGVHRDRQLLQFCYTAEVADSVLKLLDDVGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSEEGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLMLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLNYE
                     GLDASRALAFFDDEAVEQDEESLFLWMRAHPYDDLVVLDVTASEQLADQYLDFASHGF
                     HVISANKLAGASASDKYRQIHDAFEKTGRYWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLTEPDPRVDLSGKDVMRKLVILAR
                     EAGYDIEPDQVRVESLVPAHCEEGSIDHFFENGDALNEQMVQRLEAARELGLVLRYVA
                     RFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(2855..4015)
                     /gene="metB"
                     /locus_tag="OPY25_004318"
     CDS             complement(2855..4015)
                     /gene="metB"
                     /locus_tag="OPY25_004318"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCS0929767.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLATRGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKIC
                     RLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVMIAKDPEM
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPNNQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMSPQARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            4280..4597
                     /gene="metJ"
                     /locus_tag="OPY25_004319"
     CDS             4280..4597
                     /gene="metJ"
                     /locus_tag="OPY25_004319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HCS0929768.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGIDPET
                     WEY"
BASE COUNT         1133 a         1449 c         1225 g         1031 t
ORIGIN      
        1 ggggatcact tttttctttt tggcgctctc ttttatcagt tcgctgggat cgtcgtatgg
       61 tgtttatttt tggagtaaat cactgtctat tccagccgat cgtattggtc ttattctcgt
      121 tggcgtaaat ggcccatctg acgtagtcag gcttatcata gcacagcaat attgtgtctg
      181 acgcttagcg acgaaatcca aacattgcgg gcgaatgcaa acgaaaatac aggtatacag
      241 agcggctgga cgctattttg ggcattgctg ttcccccctg tcggcatagc cattatccag
      301 gcgaagatga accgatttat cgtcgccaat gcagaaaacg catctgacga agaataaaca
      361 gataccccgg tttgcccgct gccggatctg gcgaagccgc tatccggcag gcgggcgtat
      421 tacaatagct gcgccaggcg gttgatatcc gactgaatcg ccccggcggt cacatcgcga
      481 cccgcgcccg gcccacggat caccagcggg ttatcgcgat accagcggct ttcaatagca
      541 aagacattat cgcacggcag cagcgccgcc agcggatgct ccggacgcac cgcttcaacg
      601 ccgacgcgcg ctttgccatt ggcgtcgaaa cgcgccacgt aacgcaacac cagccccagt
      661 tcgcgggctg cctccagacg ctgcaccatc tgttcattca gcgcgtcgcc gttttcgaaa
      721 aagtgatcga tagacccttc ttcacagtgc gccggcacca acgattctac acgcacctga
      781 tccggctcga tgtcgtatcc cgcctcgcgc gccagaatca ccagcttacg catgacatct
      841 tttccggaaa gatcgacgcg cggatcgggt tccgtcagcc cctgctgcca ggcctgatcc
      901 accagatcgg taaacggcac cgtgccgtca aattgcagga acagccagga tagcgtcccg
      961 gagaagatcc cgctgatcga gagaatcgta tcgccgctgt caatcagatc ccgcaccgtg
     1021 tggttgatcg gcaaccccgc gcccacggtg gcgttataca gccagtaacg cccggttttt
     1081 tcaaacgcgt catgaatctg gcgatactta tcgctggcgc ttgcgcccgc cagtttattg
     1141 gcgctaatca catgaaaacc gtggctggcg aaatcaaggt actgatcggc cagttgctcg
     1201 cttgctgtca catccagcac cactaaatca tcatacggat gcgcacgcat ccacaggaat
     1261 agcgactctt cgtcctgctc aacggcttca tcatcaaaga atgccagcgc gcggctggcg
     1321 tccagccctt cataattcaa caggctacgg cggctatcca ccacgcccgc cagcacaaat
     1381 tcaaaaccag tacgcgcgga aagcgtgctt tgttcacggg caaatagttc cagccaacgg
     1441 gagccgatgt tccccttacc gaacagcatc aggccaatgc gtttttcggc gcggaaaaca
     1501 gactggtgca gcccctgaat caggctctca gtcgggccgg tacgcagcac cgccaccaga
     1561 ctgatgccct cctccgactg ccaggtaaac tccactggct gacctttcaa ctgctgccag
     1621 aagcgatggc agtgtagcgg attgcgagtg acgcccgcac cgaccatcgc caccagcgcc
     1681 agcccctgcc gcaggcgcaa ttcgcccggc agtccgacat cgtcgaggag tttcagtacg
     1741 ctatccgcta cctcggcggt atagcagaac tgcaatagct ggcgatcgcg atgcacgccc
     1801 accgccagcg gacgcgcctg cgcccgtttt aaaatttggt cgagctcttt gtgcgccagc
     1861 ctgaaatcct ggctggcggg cacctgaaac tcaatcagac agatatcatc gtgactggtc
     1921 acgatacgcg cgcccgtccc ggaagccagc actcgttcaa ttcgggttga cccttgatcc
     1981 ggcgtgtagc tacagcgcaa ctgcaaatcg atatcgctgc cggacactgg ctgtagcgtg
     2041 cgggcgtgca gaacaggcgc cgccagacgc gccagctcgc tggcttcgtc cagacgcagc
     2101 aacggcagca ggcaggcatc tttcactttg cgcgggtcgg cgctataaac gcccgcgaca
     2161 tcgctccaga tggtcacgcg ggaaacgccc gccaacgcgc cgatttgcgt ggcggaatag
     2221 tcggaaccgt tacggcctaa caggactgtt tcgccgtcgt gattgcggct gataaacccg
     2281 gtcacgacca gacgtttgcc aggatgctgc gccagtagct gttgcaataa aggataagat
     2341 agtccttcat caacctgcgg ctgtgcggcg cgttcggcgc gtaaaaatgc gcgcgcgtcc
     2401 agccaggcgg catccagccc ctgctgattc aggacggcgg acatcaatct cgccgaccaa
     2461 atttcgccgt gtccgacgat ctcagcatag acggcatccg ttacgccgcc gtcgagcaag
     2521 gcggcaagac gttccagatc gctgataaaa gcgctggtta agtcatctgc cgcgtcggcg
     2581 ggaagcagcc cgctaatcag atcgcactgg tagcggcgta acgtctgtaa tacctgatgc
     2641 gcagaaaggc gatcggtctg gcttaacttg agccagctaa tcaactggtt ggtggtactg
     2701 cctgcggcgg acactaccat catatcgtca ggctgcgaat actccgccat aatgcctgcg
     2761 acacgcaggt aacacttcac atccgccaga ctactgccgc caaatttatg cagttgacga
     2821 cctttcgccc ctgcctgcgc aatcacactc atgtttaccc cttgtttgca gcccggaagc
     2881 cattttccag gtcggcaatt aaatcttcgc catcttcaat accggtggag atacgcagta
     2941 gcgtttcgga gatcccggcg gcggcacgcg cctgcggcga cataccggca tgcgtcatgg
     3001 tggcggcgtg agagatcaaa ctttccactc cccctaaaga ttccgccagc gtaaacagcg
     3061 acagcccgcc cagaaaacga cgtagcgtct cctcatcccc atccagttca aaactcaaca
     3121 ttgcgccaaa gcctttttgc tgacgcgcgg caatctcatg tccctgatta ttcggcagcg
     3181 acgggtgata cagttttttc accaacggct gggtttgcag atatttcaca atcgcctgcg
     3241 cgttgcgctg cgccagctcc atacgcggca ccagagttcg caaaccgcgc agcagcagat
     3301 agctatcaaa cgccccgccg gtcacgccaa tattattcgc ccaccacgcc agttcagtga
     3361 ccatttccgg atccttagca atcatcacgc cggccacgac atccgaatga ccattgagat
     3421 atttcgtgca tgaatgcaac accagatcgg cacccaacgc cagcggattt tgcagcgccg
     3481 ggcttaaaaa tgtgttatca acgacgctca ctgcgcccgc ctcgcgcgcc agccgacaga
     3541 ttttcgcaat atccaccacg cgtaacaatg gattacttgg actttctacc agtaccagct
     3601 tcggtttttc ttccagcgcc gcctgtaagg cgcgttcatc gccctgatcg acaaaccgca
     3661 cacgataaca gccgcgcgtc gccagactgt caaacagacg ataactgccg ccgtagcaat
     3721 catgcggcgc gaccagcaga tcgcccggct tgaggaaaac ggtggtgacc agatgaatcg
     3781 ccgacatgcc ggtattcgtc aatactgcgc ccgcgccgcc ttccagttcc gctaatgcgc
     3841 gctgaaccac atcacgcgtg ggattaccgc ggcgggaata atcatgcgcg cgcggctcat
     3901 tgaaaccggt aaagttatag gtactggaga gatggattgg cggcacaacg cagccgtatt
     3961 gttcgtcatc gtttaatccg ctacgcactg cgatagtggc ctgtttacgc gtcatatgaa
     4021 gatattcctg gctgagtcgg tgaaagtcag gccacagatt aaccactacc acaatagacg
     4081 tcaatacatc tggacatcta aacttctttg cgtatagatt gagcaaaccg caaatagccg
     4141 ttaaaattat atgcattagc gcacatctgc gaccgctaac ttcgtgtcag ggccgcgcca
     4201 ctacggtaaa ctacgcgcga ttatggtccg ggctcaggtt cagacctcaa tattaatgac
     4261 gaagaggatt aagtatctca tggctgaatg gagcggcgaa tatatcagcc catacgctga
     4321 gcacggtaag aagagtgagc aagtcaaaaa aattacggtt tccattcctc tgaaggtgtt
     4381 aaaaatcctc accgatgaac gtacgcgtcg tcaggtgaac aacctgcgcc acgccaccaa
     4441 cagcgagctg ttgtgtgaag catttctgca cgcctttacc gggcaaccct tgccggatga
     4501 tgccgatctg cgaaaagagc gcagcgatga aatcccggaa gcggcaaaag agatcatgcg
     4561 tgagatgggg attgacccgg aaacgtggga atactgatag caaagcatgc ggtcagaacg
     4621 cctctggccg cgctttttta acgatttccc ctgtacacgg ctatctccga cattgttcta
     4681 aacgttcatc ttcccgaata gccctcggtg gataaatttg tcagacatga taagtttctc
     4741 ttcgttattt tcctgaaaaa attcccggca tgccataatc gatataattt tattatattt
     4801 aaaattccaa tatttattta atgtttcacg tagcaaag
//
LOCUS       DAJVKX010000210         4833 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.210, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000210 DAJVKX010000000
VERSION     DAJVKX010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4833
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.210"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            112..1140
                     /gene="murB"
                     /locus_tag="OPY25_004320"
     CDS             112..1140
                     /gene="murB"
                     /locus_tag="OPY25_004320"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCS0929769.1"
                     /translation="MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVM
                     ILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWHLHVGAGENWHQLVRYALDNNMP
                     GLENLALIPGCVGSSPIQNIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRD
                     SIFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVAADIAMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKG
                     VTIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNVWLEPEVRFIGQFGE
                     VNAVESIA"
     gene            1137..2099
                     /gene="birA"
                     /locus_tag="OPY25_004321"
     CDS             1137..2099
                     /gene="birA"
                     /locus_tag="OPY25_004321"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HCS0929770.1"
                     /translation="MKDTTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLDADRIHSQLDSGNVAVLPVIDSTNQYLLDRIGELR
                     SGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMYWRLEQGPAAAIGLSLVIGIVMAEV
                     LRELGADKVRVKWPNDLYLLDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEEDV
                     INQGWITLQEAGITLDRNMLAAKLIYKLRAALELFEQEGLSPYLSRWKKLDNFIDRPV
                     KLIIGDKEIFGISRGIDTQGALLLEQDGVIKPWMGGEISLRSAE"
     gene            complement(2134..3084)
                     /gene="coaA"
                     /locus_tag="OPY25_004322"
                     /gene_synonym="panK"
     CDS             complement(2134..3084)
                     /gene="coaA"
                     /locus_tag="OPY25_004322"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCS0929771.1"
                     /translation="MSIKEQSLMTPYLQFDRSQWAALRDSVPMTLTEDEIAQLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPEGDKTVAQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEELLQTWYINRFLKFREGAFTDPDSYFHNYAKLSKEEAVNTAAS
                     LWKEINWLNLKQNILPTRERASLIMTKSANHAVEQVRLRK"
     gene            complement(3293..3466)
                     /locus_tag="OPY25_004323"
     CDS             complement(3293..3466)
                     /locus_tag="OPY25_004323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929772.1"
                     /translation="METCVLMQLKNCIKCSIAHILRYKRQKCSNFKQESINFRHFTNR
                     LTRIRRGISTLRR"
     gene            3486..3561
                     /locus_tag="OPY25_004324"
     tRNA            3486..3561
                     /locus_tag="OPY25_004324"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3519..3521,aa:Thr,seq:tgt)
     gene            3570..3654
                     /locus_tag="OPY25_004325"
     tRNA            3570..3654
                     /locus_tag="OPY25_004325"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3604..3606,aa:Tyr,seq:gta)
     gene            3771..3845
                     /locus_tag="OPY25_004326"
     tRNA            3771..3845
                     /locus_tag="OPY25_004326"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3804..3806,aa:Gly,seq:tcc)
     gene            3852..3927
                     /locus_tag="OPY25_004327"
     tRNA            3852..3927
                     /locus_tag="OPY25_004327"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3885..3887,aa:Thr,seq:ggt)
     gene            4043..>4833
                     /gene="tuf"
                     /locus_tag="OPY25_004328"
     CDS             4043..>4833
                     /gene="tuf"
                     /locus_tag="OPY25_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCS0929773.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ
                     YDFPGDDTPIVRGSALKALEGDAEWEAKIIELAGFLDSYIPEPERAIDKPFLLPIEDV
                     FSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFR"
BASE COUNT         1221 a         1148 c         1268 g         1196 t
ORIGIN      
        1 gcaagttcgg cacaatgcct gtgtacaccg ccttattccg tcgacataac cgcaagcctt
       61 cccaacccag atacggtaaa ctattgccga ttgagtatca ggaaagcagc catgacccat
      121 tccctaaaac cctggaatac cttcggcatt gatcattgtg caaagcacat cgtatgcgct
      181 gaaaacgaac aacaactact gagcgcctgg cagcaagcaa ctcgtgaggg actgccggtt
      241 atgatcctgg gtgaaggaag caacgtcctg tttctggaaa attacgccgg caccgtgatc
      301 cttaaccgcc tgaaaggcat tgaggtgaat gaaaccgcgg acgcctggca cctacacgtc
      361 ggcgcaggcg aaaactggca tcagctggtt cgctatgcgc tggacaacaa catgcccggc
      421 ctggagaatc tggcgctcat ccctggctgc gttggttcct cgcctataca gaatattggc
      481 gcgtatggcg tagaactaca tcgcgtctgc gactacgttg actgcgttga actggaaacg
      541 ggaaaacgtc tgcgtttgtc cgcggcggaa tgccgtttcg gctatcgtga cagtatcttc
      601 aaaaatgaat atcaggatcg cgttgcgatc gtcgcggtgg gtctgcgttt gtcaaagcaa
      661 tggcagccgg tgttgaccta tggcgatctt actcgtctgg acccgaaaac ggtcaccgcg
      721 caacaggtgt ttgatgctgt atgccatatg cgcaccacaa aattgccgga tcctaaagtg
      781 aatggcaatg cgggcagctt ttttaaaaat cccgttgtcg cagccgatat cgctatggaa
      841 ctgttagaac gatttcccaa cgcgccgcat taccctcagg cagacggctc agtgaagctg
      901 gcggcaggct ggctgataga tcaatgtcag ttgaaaggcg tcaccattgg cggcgctgcg
      961 gtgcatcgcc aacaggcgct ggtattgatt aatgcgaatg atgcgacaag taaagatgtg
     1021 gtggcgctgg cgcatcatgt ccggcaaaaa gtgggtgaaa aatttaatgt ctggctggag
     1081 cctgaggttc gctttattgg tcagttcgga gaggtgaacg ctgtggagag cattgcatga
     1141 aagatactac cgttcccctg acgctgatct cactacttgc cgacggagag tttcactcag
     1201 gcgagcagtt gggtgaacgg ctgggaatga gccgtgcggc tattaataaa catatccaga
     1261 cattacgcga ctggggagta gatgtattta ccgttcccgg gaaaggatat agcttaccgg
     1321 aacccatcca gttactggat gctgaccgta tacatagcca actggatagc ggaaacgtgg
     1381 cggtattgcc cgttatcgat tcaaccaatc agtatttact tgatcgaatt ggcgagctgc
     1441 gttcaggcga tgcctgtgta gcagaatacc aacaggcggg gcgtggtcgt cgcgggcgta
     1501 aatggttctc accgtttggt gcgaatctat atctttcaat gtactggcgt ctggagcagg
     1561 ggcctgcggc ggcaataggc ttgagtctgg tcattggaat tgtgatggcg gaagtgctgc
     1621 gtgaactggg cgcagataaa gttcgtgtga agtggcctaa cgacctttac ctactggatc
     1681 gcaaactggc gggtattctg gtcgagttaa ccggtaaaac gggcgatgcc gcacaaatag
     1741 tgattggcgc tggtattaac atggcaatgc gtcgtgtaga agaggacgtg ataaatcagg
     1801 gatggatcac actacaagag gccggaatta cgctcgaccg caatatgctg gccgcaaagc
     1861 tgatttataa gctacgtgct gcgcttgagc tttttgagca agaaggtctt tctccttatc
     1921 tttcgcgctg gaaaaaactg gataatttta ttgatcgtcc ggtaaaacta attattggcg
     1981 acaaagaaat atttggtatt tcccgcggca ttgatactca gggcgcatta ttgcttgaac
     2041 aggatggcgt gattaaaccc tggatgggcg gagaaatatc gctgcgaagc gccgaatagt
     2101 aaaaaagggg agtcggtact cccctttttt ctgttatttc cgcaatctta cctgttccac
     2161 cgcatggtta gcgctcttgg tcataataag gctggcacgt tctcgcgtag gtaagatatt
     2221 ttgttttaaa ttcaaccagt taatttcttt ccaaagcgaa gctgctgtat taacagcttc
     2281 ttctttagat aatttcgcat aattgtggaa ataagagtca ggatcggtaa acgccccttc
     2341 gcggaatttc aggaagcgat tgatatacca cgtctgaaga agttcttctg gcgcatcaac
     2401 gtaaatagag aaatcaacga aatcagagac aaatacatgg tgcggatcgt gaggataatc
     2461 cataccgctt tgtaaaacat tcaaaccttc aagaatcaat atatcaggct gagcgacggt
     2521 tttatcccct tcaggaataa catcgtaaat caaatgagaa tagactggcg ccgtcacgtt
     2581 cggtacgccc gacttgaggt cagaaacgaa tttcaccagt cggtgcatat catacgattc
     2641 ggggaacccc tttttcttca ttaacccgcg ttctttcaac acctggtttg ggtggaggaa
     2701 gccgtctgtg gtaatcaatt caacacggcg gtgttccggc cagcgactca gcaacgcttg
     2761 cagaacgcgt gctgtcgtgc ttttacccac tgcgacgctg cccgcgatac tgatgatgta
     2821 agggattcgc tggccgttag tgcccagaaa ctgttccagg acagcctgac gacgcagatt
     2881 tgaactgata tagaaattta gcaaacggga gagaggtaaa tatatttctg caacttcttc
     2941 cagcgataaa tcttcattaa tgccttttaa ctgcgcgatc tcatcctcgg tcagggtcat
     3001 cggcacagaa tcgcgaagcg cagcccactg gctgcgatca aactgtaggt aaggcgtcat
     3061 taacgattgc tcttttatac tcataagcat gtttctggct gctattgcta catcagttca
     3121 gcgatgaacg agggccatcc ctgacatgca acggcacgtc acatttaagt taatttggac
     3181 aatgggcagg agggtaacac cagatgggga ggaataataa gaaaaaatct cgctgtgaaa
     3241 gctatccctg agaagcaatg tgacgaatat accagataca gaagattgct ttctatcgac
     3301 ggagcgttga aatgccgcgt cgtatcctgg tcagacggtt ggtaaaatgc cgaaaattta
     3361 tgctctcttg tttgaaatta gagcattttt gtctcttata gcgcaaaatg tgagcgatag
     3421 aacattttat gcaatttttt agttgcatga gcacgcaggt ctccatagaa tgcgcgctac
     3481 ttgatgccga cttagctcag taggtagagc aactgacttg taatcagtag gtcaccagtt
     3541 cgattccggt agtcggcacc atcaagtccg gtggggttcc cgagcggcca aagggagcag
     3601 actgtaaatc tgccgtcaca gacttcgaag gttcgaatcc ttcccccacc accattttcg
     3661 gccgcgcgat ggcgcagccc gagacgataa gttcgcttac cggctcgaat aaagagagtt
     3721 tctctcgata ttcagtgcag aatgaaaatc aggtagccga gttccaggat gcgggcatcg
     3781 tataatggct attacctcag ccttccaagc tgatgatgcg ggttcgattc ccgctgcccg
     3841 ctccaagatg tgctgatata gctcagttgg tagagcgcac ccttggtaag ggtgaggtcg
     3901 gcagttcgaa tctgcctatc agcaccactt cttttctcct tcctgttttt ctcttctgtt
     3961 tattagcatt caacaagtcg ggcgtgttgc ctggttgatg tggtgatatc accgatttat
     4021 ccgtgtctta gagggacaat cgatgtctaa agaaaagttt gaacgtacaa aaccgcacgt
     4081 taacgtcggt actatcggcc acgttgacca tggtaaaaca acgctgaccg ctgccattac
     4141 taccgtactg gctaaaacct acggcggtgc cgcccgcgca ttcgaccaga tcgataacgc
     4201 gccggaagaa aaagcgcgtg gtatcaccat caacacttct cacgttgaat acgatacccc
     4261 gacccgccac tacgcacacg tagactgccc ggggcacgcc gactatgtta aaaacatgat
     4321 caccggtgct gctcagatgg acggcgcgat cctggttgtt gctgcgactg acggcccgat
     4381 gccgcagacc cgtgagcaca tcctgctggg tcgtcaggta ggcgttccgt acatcatcgt
     4441 gttcctgaac aaatgcgaca tggttgatga cgaagagctg ctggaactgg ttgaaatgga
     4501 agttcgtgaa cttctgtctc agtacgactt cccgggcgac gacacgccga tcgttcgtgg
     4561 ttctgctctg aaagcgctgg aaggcgacgc agagtgggaa gcgaaaatca tcgaactggc
     4621 tggcttcctg gattcttaca tcccggaacc agagcgtgcg attgacaagc cgttcctgct
     4681 gccgatcgaa gacgtattct ccatctccgg tcgtggtacc gttgttaccg gtcgtgtaga
     4741 acgcggtatc atcaaagtgg gcgaagaagt tgaaatcgtt ggtatcaaag agactcagaa
     4801 gtctacctgt actggcgttg aaatgttccg caa
//
LOCUS       DAJVKX010000211         4797 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.211, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000211 DAJVKX010000000
VERSION     DAJVKX010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4797
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.211"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            90..389
                     /locus_tag="OPY25_004329"
     CDS             90..389
                     /locus_tag="OPY25_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929774.1"
                     /translation="MSITSLIGEVNHLDEYSGFLQNLYLSGGRRIAIVLAVRPGVSGW
                     MRRTLHQLVYCTVGPVPLDSLICQFGPGECSKSSGTSLPCGFRTSPAGDSGGKIA"
     gene            507..1295
                     /gene="fabI"
                     /locus_tag="OPY25_004330"
     CDS             507..1295
                     /gene="fabI"
                     /locus_tag="OPY25_004330"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCS0929775.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSSIVLPCDVAEDASIDAMFAELGNVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRTMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            1495..2415
                     /locus_tag="OPY25_004331"
     CDS             1495..2415
                     /locus_tag="OPY25_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCS0929776.1"
                     /translation="MEQCRKAGKSHWYHETQSTMSSQTPLSLMPEAAYVNDRFLLDLA
                     VAETALTPFESWLKPARQLADVLFPRTVLNDRLHTFSAYERMSTALTAAQVFGVQRLC
                     RHYAARLAPLPGPDASRESNQRLAQITQYARQLAGSPSVINTRAREQLAEVGLTARDT
                     VLINQIIGFIGFQARVAAIFQAFCRLPVRELPGQEMQRFARAARFQNPQTTWRPAASL
                     VEYPLAHTKVRRQYSSSQCQIMAPVLMRDPSSFALLERILTSTLHTASPPSLLPLITL
                     LTSRINGSAACFNEQATQPGAWRRAVITLR"
     gene            2717..4651
                     /locus_tag="OPY25_004332"
     CDS             2717..4651
                     /locus_tag="OPY25_004332"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HCS0929777.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPD
                     HPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVP
                     WWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELA
                     DGRLQLTVAIADPTAWIAEGSKLDNAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPALACRMIIAADGTIDDDIAFFAATIESKAKLVYDNVSDWLENNSTWQPENEGIA
                     QQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEES
                     MIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFC
                     KLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAA
                     EIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVI
                     DVTIAEVRMETRSIIARPAA"
BASE COUNT         1088 a         1299 c         1260 g         1150 t
ORIGIN      
        1 tcagtattac tctgcatcaa taaatagaga aaaccttcag cgcctaaaaa agaaattatt
       61 tttgttaagc atttgctggt taaaattaca tgtccataac atcgctaata ggtgaggtaa
      121 accatttgga tgaatattca ggcttcctac agaaccttta tttgtctggt ggaaggcgca
      181 tcgctatcgt acttgctgtc cgtcccggtg tctctggttg gatgaggcga accttacacc
      241 agctggtata ctgcaccgta gggcctgtcc cattagactc tttgatttgc cagtttggcc
      301 ctggggagtg ctcaaaatcc tcagggactt cgttaccgtg tggttttaga acgtcacctg
      361 ccggagatag cggcggaaaa atagcgtgac acacggggcc aggagtggga tataatttca
      421 gactaatttc gaataatgtt gaaaagttgc tgttaaccat tgttcgtaaa agcaaaaaat
      481 aagcaatgac tataaggatt aaagctatgg gttttctttc cggtaagcgc attctggtca
      541 ctggcgtggc cagtaaactg tccatcgcct acggtatcgc acaggcgatg caccgcgaag
      601 gagctgaact ggcgttcacc taccagaacg acaaactgaa aggccgcgta gaagaatttg
      661 ctgcccagct gggttccagc atcgttttac cgtgtgatgt cgctgaagat gccagcattg
      721 acgctatgtt tgcggagctg ggtaacgttt ggccgaaatt tgacggtttc gttcactcga
      781 tcggtttcgc gcctggcgat cagctggacg gcgattatgt taatgcggtt acccgcgaag
      841 gctttaaaat cgctcacgat attagctctt acagttttgt tgccatggcg aaagcctgcc
      901 gcaccatgct gaatccgggt tctgcgctgt tgaccttgtc ttatctggga gcggagcgcg
      961 ccatcccgaa ctacaatgtc atgggtctgg cgaaagcctc tctggaagcc aacgtgcgtt
     1021 atatggcaaa cgctatggga ccggaagggg ttcgcgtcaa cgccatctct gcgggcccga
     1081 tccgcacgct ggcggcgtcc ggtattaaag acttccgtaa aatgctggcg cattgtgaag
     1141 ccgttacgcc aattcgtcgc accgtgacca ttgaagatgt gggtaactca gcggcgtttc
     1201 tgtgttccga tctctcggca ggcatttctg gcgaagtcgt ccatgttgac ggcgggttca
     1261 gcattgcggc aatgaatgaa ctggaactga agtaagcgca ttaagtttat tagcgggcgg
     1321 cacggctgtg ctgccccatt cccctcactc accgctcatc tcgttatata gcgttctgat
     1381 atttgttatc acctaacaat ctttcatccc tttcccgcat acgccaggat aatccagcat
     1441 aaacgatccg acgccgaatc attatcgatc gccatttcat cctcgggaaa ccctatggaa
     1501 caatgccgaa aagcgggtaa aagccactgg tatcatgaaa cacaatccac tatgtcgtca
     1561 caaactccgc tttcgctgat gccggaagcc gcgtatgtta acgatcgatt tttactggat
     1621 ttagcggtag cagaaaccgc gttgacgcct tttgagtcat ggttaaagcc agctcgccag
     1681 ttggcggatg tcttatttcc ccgcacggtt ctcaacgacc ggcttcatac gtttagcgcc
     1741 tatgaacgta tgagcaccgc ccttaccgcc gctcaggtat ttggggttca gcgtttgtgc
     1801 cgccattatg ccgcacgtct ggcgccgcta cccggccctg acgcctcaag agaaagcaat
     1861 caacggctgg cgcaaattac gcaatacgct cgtcagcttg ccggctcccc ctccgttatc
     1921 aatacgcgag cccgcgaaca gcttgcagag gtgggattaa ccgcccggga taccgtactc
     1981 atcaatcaga tcattgggtt tatcggtttt caggcgcgag tagcggcgat atttcaggcg
     2041 ttttgccgtc tgcccgtgcg cgagctgccc ggccaggaga tgcagcgctt tgccagggcc
     2101 gcgcggtttc aaaaccccca gacgacatgg cggcccgccg ccagtctggt agaatatcct
     2161 ctcgcccata ccaaagttcg gcggcaatat tcgtcttcac aatgccaaat aatggcgccg
     2221 gtactcatgc gcgatccgtc ttcattcgcg ttactcgaac gcatactgac cagcacatta
     2281 cacactgcgt cgcccccttc tttacttcca cttatcacgc tcctcacatc acgtatcaac
     2341 ggcagcgccg cctgctttaa cgaacaggca acccaacctg gcgcgtggcg ccgtgctgtc
     2401 atcacgttac gctaggaaga cgacgacatc gctcgttggg aacttgagcc cgcgctgaca
     2461 caggcgatac aatggctcac cagagcgccc gatcgcttta gcgccgcgca ttttttcccg
     2521 ctactcacca ggggagtttc atcggagcag gccattaata tgttaggctg gtgtggcgtg
     2581 tgcggatggt taaatcgttt aaaaatcgcg ttgggcgaaa cctattaact catccattac
     2641 tgaaagagcg cttgctgcgc caggcagaat cgcgtaaaac tgtcagccgc tcttttggct
     2701 acgaaaatag acgaatatgt ttcaggacaa cccgctgcta gcgcagctta aacagcaact
     2761 gcattcccag acgccgcgcg ctgaaggggt cgtaaaagcc acggaaaaag gctttggctt
     2821 ccttgaggtt gacgcgcaaa aaagctactt cattcctccg ccgcagatga aaaaagtgat
     2881 gcatggcgat cgtatcgtcg cggtcatcca cacggaaaaa gaacgtgagt ctgccgagcc
     2941 ggaagaactg atcgaaccgt tcctgacgcg ctttgtggga aaagttcagg gtaaaaatga
     3001 ccgcctgtcc atcgtgccag atcatccgtt gctgaaagac gcgattccct gccgcgccgc
     3061 gcgcggcgtt cagcatgagt tcaaagaagg tgactgggcg gttgccgaaa tgcgccgcca
     3121 tccgcttaaa ggcgaccgtt cgttttacgc cgatttaacg cagtacatca cctttgccga
     3181 cgatcacttt gttccctggt gggttacgct tgcccgccat aacctggaaa aagaagcgcc
     3241 gaacggcgta gcgacggaga tgctggacga agggctggag cgccaggatc ttaccgcgct
     3301 gaatttcgtc actatcgata gcgccagcac tgaagatatg gatgacgcgc tttatgctga
     3361 ggaattagcg gacggcagac tccagcttac ggtggctatc gccgatccta ccgcctggat
     3421 tgccgaaggc agtaagctgg ataacgccgc gaaaattcgc gccttcacca actacctgcc
     3481 gggcttcaat attcctatgc tgccacgtga gctgtctgac gatctgtgtt cgctgcgcgc
     3541 caacgaagtg cgtccggcgc tcgcctgtcg catgatcatc gccgcggacg gcaccattga
     3601 cgatgatatt gccttttttg cggccaccat cgaatcgaag gccaagctgg tgtacgacaa
     3661 tgtctccgac tggctggaaa ataacagcac ctggcagccg gagaacgaag gcattgccca
     3721 gcagattcgt ctgttgcacc gtatttgtct aagccgcagt gagtggcgtc atcatcatgc
     3781 gttagtcttt aaagaccgcc cggattaccg ctttgtgctt ggcgaaaaag gcgaagtact
     3841 ggatattgtg gcggaaccgc gccgtatcgc taaccgtatc gtagaagagt cgatgatcgc
     3901 cgctaacctt tgcgccgcgc gcgtactgcg cgataagctc ggtttcggta tttacaacgt
     3961 acatacgggc ttcgatcccg cgaatgccga cgcgctggcc gcgctgctga aaacgcatgg
     4021 tctgcatgtc gatgccgaag aggtgctgac gctggaaggc ttctgtaaac tgcgtcgcga
     4081 actggatgcg cagccctccg gtttccttga cagccgcatt cgtcgcttcc agtcttttgc
     4141 ggaaatcagc accgagccgg ggccgcattt cggtcttggt cttgaggctt atgccacctg
     4201 gacctctccc atccgtaagt atggcgatat gattaaccat cgcctgctga aagcggtcat
     4261 caagggggaa gctattgcgc gtccgcagga agatatcacc cagcaaatgg cggaacgccg
     4321 tcgcctgaac cgcatggcgg agcgcgatgt cggcgactgg ttatatgcac gcttccttaa
     4381 cgataaggcg gggacaaata cccgtttcgc ggcagaaatt attgacgtca gccgcggtgg
     4441 tatgcgtgtg cgactggtcg ataacggcgc tatcgccttt atccctgccc cgttcctgca
     4501 cgccgttcgc gatgaactgg tatgcagcca ggaaaacggt acggtacaga ttaaaggtga
     4561 gacggtttat aaagtgacgg atgtcattga tgtcactatt gcggaagttc gcatggaaac
     4621 ccgcagcatt attgcccgac cggcagcgta accacgctta gctcgctcaa cggcctttgc
     4681 tgagaaggca aaggccgttt cttttcttct tctcccttcc gtcatgctct aagtttaatc
     4741 ttattcaagc gccccatttc ttgttatttt tagctggcga ctatgctttt tccagaa
//
LOCUS       DAJVKX010000212         4796 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.212, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000212 DAJVKX010000000
VERSION     DAJVKX010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4796
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.212"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            352..1365
                     /gene="trpS"
                     /locus_tag="OPY25_004333"
     CDS             352..1365
                     /gene="trpS"
                     /locus_tag="OPY25_004333"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCS0929778.1"
                     /translation="MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIAD
                     LQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPALTTICLQSALPALAELTVLYMNIVT
                     VARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
                     TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLVNTLLLSASEETIHR
                     AVSAMYTDPNHLKISDPGKIEGNVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKN
                     ELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQKTLQEVKRGLGLPTL
                     FQV"
     gene            complement(1366..2139)
                     /gene="uxuR"
                     /locus_tag="OPY25_004334"
     CDS             complement(1366..2139)
                     /gene="uxuR"
                     /locus_tag="OPY25_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HCS0929779.1"
                     /translation="MKSNTSQQRPYQEVGAMIRDLIVQTPYRPGERLPPEREIAERLN
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSADNNEMEGADVNHCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIIKMRQALQLEERELASSAPGGSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWLQLHSHLGDTLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFESWPLDNVDA"
     gene            2489..3154
                     /locus_tag="OPY25_004335"
     CDS             2489..3154
                     /locus_tag="OPY25_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HCS0929780.1"
                     /translation="MIKDTVFFAPSVSGGSNASSLSSRHRRAAIILHEIYGINAHIQR
                     AGHEWMTRGFDIYIPALFPHHTPFRYEQQEEAYRHFSANVGFDPAVVTTLLHDLRAQY
                     ETLIVVGYSVGATLAWLSAASGLCDGVICYYGSRIRQYLHLAPLCPALVIIARYEPAF
                     DPRAMRQTLEKRPRVQCKMYDARHGFCDADSATFDAALSHQVMDDVSAFIRDITCANT
                     SPD"
     gene            complement(3171..3632)
                     /locus_tag="OPY25_004336"
     CDS             complement(3171..3632)
                     /locus_tag="OPY25_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF302 domain-containing protein"
                     /protein_id="HCS0929781.1"
                     /translation="MSTILKPFLSAVTLMLILIRPGFATEDGAITMVKTYSAYDYLQT
                     RARLMHAVADHGLVLFGEFDHARAAQNVNLKMPPTTVLVFGNPKGGTPLMLAHPELAL
                     DLPFRVLISQQADGRTLVSYHPAETLQRYGLDAADIQALKKLEQLVEKSLH"
     gene            complement(3843..4754)
                     /locus_tag="OPY25_004337"
     CDS             complement(3843..4754)
                     /locus_tag="OPY25_004337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929782.1"
                     /translation="MHTFRPYLLRHSDLLYEDIPLEIREQIILLIINTLGNCSSFYDM
                     TLYCYHNSHSDEVYRRICKTLRKEYGLFTLYAHSTSYLDEMSNLLLKTDDKRKHIDTI
                     ELAFNYIDTYLRTYEVTLGLEPDKAISELNNIFHEHSLKYRYENGRIVRLRRIKRLKN
                     ICYYLYSPGEYGFVEYDLMEAYNRLMLNDFACVVRECHAVFRSVLLRIHERKSIVYHE
                     QDSLNTLMANLMARGVISAEYVHKFHFLIDVLESEIFLPMAPEKSHHHHAMMLRISEE
                     LACSIYYLTERSIFFLTQRAEEDGVAP"
BASE COUNT         1273 a         1238 c         1068 g         1217 t
ORIGIN      
        1 cagtgttatc acagtaataa atgacttgca tcaaaaatgc gcctttcagc gccacgtatt
       61 tttgggcagc aaattataaa atcgcgtttc aaagtcagtg acatgttctc tgtgcaggcg
      121 atatgacttt atgcccggac gacacgccag ccgctttacc cttacgttta gtcgtgatac
      181 gttagaccac atgaacacga aacgatccaa cgctacgcaa cgtcatctcc gctggtggct
      241 gccttcctga aggcggcacg gatcactatc cctttttaag tagccgccga aaggcggcta
      301 ctgcgtttcg ggacgtcttt cggctttaca gtaagcataa aggagtcctt aatgaacacc
      361 cttcctatca ttctgactgg cgatcgcccc accggctcgc tgcacctcgg ccattatgtc
      421 ggttcactgc gccagcgcgt cgcgctacag caggatcacc aacagtatgt cctgattgcc
      481 gacctgcagg gactcaccga taacggcagt aatccgcaaa aaatccgcga taatattccg
      541 caagtgttag ctgactatct ggccgtcggc atcgatcccg cgctaacgac gatctgcctg
      601 caatccgcat tacccgccct cgctgaatta acggtgctgt atatgaatat tgttaccgtc
      661 gcccgagtgg agcgtaatcc tacggtaaaa aatgagattg cccaaaaagg ctttacccgt
      721 tccctgccgg tcgggttcat ggcgtatccc attagccagg cggcagatat caccgccttt
      781 aaggccgaaa tggtaccggt tggcgacgac caattgccca tgattgagca aacgaatgag
      841 atcgttcata agatgaatag tcttttctcc tcgccggtat tgcgaccctg tcaggcgctc
      901 ctgagcgata cgggccgtct gccaggcatt gacggcagcg ccaagatgtc gaaatcgctc
      961 gtcaataccc tgcttctttc cgccagcgaa gaaaccatcc accgtgcggt cagcgcgatg
     1021 tacaccgatc ccaatcattt aaaaattagc gatccgggaa aaatagaagg taacgtcgtc
     1081 tttacgtggc tggatgcgtt ccatccggat aaagccaaag tcgcggcgat gaaagcacat
     1141 tatcaacaag gcggattagg cgatcgtgtc tgtaaaaatg agctggagac ctgcctgcaa
     1201 gaactgatcg cgccaatacg cgaacgacgg gcaaccttta ttgcagataa gggaatgcta
     1261 atggaattac tgaaaaaagg tagcgagcgg gcgcatgagg tcactcaaaa gacgctacag
     1321 gaagtaaaac gtggactggg tctgcccacg ctattccagg tataatcagg catcaacgtt
     1381 gtccagcggc catgactcaa acagatagcc atcaaagtag atgtcatcaa cattggaaaa
     1441 ctccagcaga cgctgcttca cgttttccag gtgctgccac atcgccagct tcgctgcgcg
     1501 ggcgtctttc ttaattaacg ccgcgaggat ctgcttatga tcgcccagcc actccttacg
     1561 gtaaagcgta tcgcccagat ggctatgaag ctggagccac atcggattat tttcacgcca
     1621 ttgccaggac tgacggaaga gctcgaccaa catactgtta tgggtcgctt cggcaatggc
     1681 cagatgaaac tgcatatcgc cgctttctga gccgcccggc gcgctggagg cgagttctcg
     1741 ctcttccagt tgtaacgcct ggcgcatttt aatgatgtcc tcgcgggtgg cctgcagagc
     1801 ggcaaattca gcgatattac tttccagcaa ctgacgcgcc tgtaacagtt caaacggccc
     1861 ggcgtcatta cagtgattga cgtcagcgcc ttccatctcg ttattatccg cgctgtcgag
     1921 cacgtagatc ccggcgccgc ggcggacttc aaccagacct ttaatttcca gcatgatcag
     1981 cgcttcacgc acgacggtac gcgtcacatt gagcctctca gcgatctctc tttccggcgg
     2041 caagcgctcc ccggggcggt acggcgtctg cacaatcaga tcccgtatca ttgcgcccac
     2101 ttcctggtaa ggtctttgct gagaagtgtt tgatttcata ttggtcgtgc ccgtccgatg
     2161 cgatttcccg gtatcagact atagcatttg taaagaggga tagcacgcgt agcacaccaa
     2221 aaacgcgaaa ctggtcaacc aacaaaacaa taatgcgccc cgtttcgtta gtgaagccag
     2281 atgaaaggaa aggcagtaga caatacacga ctgatgttcc acctttagcc ctgatgcctg
     2341 aatatgaaca acatattggt ttaccaatat aaaatttatc aaccaaaaat tacgccataa
     2401 aatgtgtctg tacattgaca ggaacaacgc ctctgacata gcgtgatcgg cgaaaatcca
     2461 gccgctctct ttgtatcaag aacgcgttat gataaaagac acagtgtttt tcgccccaag
     2521 cgtatccggg ggaagcaacg cctccagttt gtcgagccgc catcgccggg cagcgattat
     2581 tctgcatgaa atttatggta ttaacgctca tatccaacgc gcaggccatg aatggatgac
     2641 gcgcggattc gacatctata ttcccgcgct gtttcctcac cataccccct ttcgctatga
     2701 acagcaggag gaggcttacc gtcacttttc agcaaatgtc ggctttgatc ccgccgtcgt
     2761 taccacgtta ctccacgatc tcagagcgca gtacgagacg ttaatcgtcg taggatatag
     2821 cgtcggcgca acgctcgcat ggctaagtgc agccagtggg ttatgcgatg gcgtcatttg
     2881 ctattacggt tcccgtatac gccagtacct tcatcttgcg cctctctgtc cggcactggt
     2941 tattatcgcg cgttatgagc cggcgtttga tccccgcgcc atgcgacaga cgctggaaaa
     3001 gcgcccccgg gtgcagtgta aaatgtacga tgcgcggcac gggttctgtg atgctgatag
     3061 cgccaccttc gatgccgcct tatctcatca ggtaatggac gatgtgagcg catttattcg
     3121 cgacatcact tgtgcaaaca catcgcccga ttgaagcctg attttcagct ttagtggaga
     3181 cttttttcaa cgagctgttc cagttttttc aaagcctgta tgtctgcggc atcaagacca
     3241 taacgttgca gcgtttcagc ggggtgataa ctgactaacg ttcgcccatc ggcttgctgg
     3301 ctaatgagca cccgaaacgg taaatccagc gccagttcgg gatgcgccag catgagaggc
     3361 gttccgcctt taggattgcc aaagaccaga accgttgtcg gcggcatttt caggttaaca
     3421 ttctgtgccg ctctggcatg gtcaaattcc ccaaataaca ccagaccgtg atcggcgaca
     3481 gcgtgcatca accgcgctcg ggtctgcaaa tagtcataag cgctgtaggt tttaaccatg
     3541 gttatcgctc catcctccgt tgcaaagcca ggccttatta agattaacat cagggttacc
     3601 gccgataaaa aaggctttaa aatagtactc attcttctct ctccctgacc caatacccat
     3661 gagtaaatgc gacacagatg atatgcggtt taaaaatcag tcatcgtact gtacccctta
     3721 ttattgcact gaacagctca tcactaaaaa aacagacggc agaacaaaaa attccgacgt
     3781 ctgaacaaat ttaaataacg atgatccaat ctgactgagc gacagcgcga tcattattat
     3841 gattatggcg cgacaccatc ctcttcagcc cgctgggtaa gaaaaaatat actccgctca
     3901 gtaagataat aaatactaca ggccaactct tcagagatac ggagcatcat tgcgtggtga
     3961 tgatgcgact tttctggcgc catcggcaga aatatttctg actccagcac gtcaattaaa
     4021 aaatgaaatt tatgtacata ttcagcagat ataacgcctc tcgccatcag attagccatt
     4081 agtgtattta aactatcttg ttcatgatat acgatacttt ttctctcatg aattctgagg
     4141 agaacgcttc tgaagactgc atgacattcc cttacgacac aggcaaaatc attaagcatc
     4201 aggcgattat acgcttccat aagatcatat tcgacaaagc catactctcc aggagagtac
     4261 aaataataac atatgttttt aagccgtttt attctgcgca accttacaat tctaccattt
     4321 tcatatcgat attttaaact atgctcatga aatatattat ttaattcact aatcgcctta
     4381 tctggttcta acccaagcgt aacttcgtag gtccgaaggt aggtatctat atagttaaaa
     4441 gcaagctcaa tggtatcaat atgctttctt ttatcatctg tttttaataa cagattactc
     4501 atttcatcca gatatgacgt tgaatgcgca tataaggtga ataagccata ctctttgcgc
     4561 aacgttttac atattcttcg ataaacttcg tcagaatgac tattatgata gcagtataat
     4621 gtcatatcat aaaaagagga gcaattccct aatgtattaa taatcaataa gattatttgc
     4681 tcgcgtattt ctaacggaat atcttcatat aacagatcgc tatgccttag taagtatggt
     4741 ctaaaggtgt gcattcctcc ccctgtaacc gcaacagaaa aaattacgct atgaat
//
LOCUS       DAJVKX010000213         4748 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.213, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000213 DAJVKX010000000
VERSION     DAJVKX010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4748
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.213"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            45..752
                     /locus_tag="OPY25_004338"
     CDS             45..752
                     /locus_tag="OPY25_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCS0929783.1"
                     /translation="MRYFFMAEPIRAMEGDLLGVEITTHFASSPARPLHPEFVISSWD
                     NSQKRRFLLDLLRTIAAKHGWFLRHGLFCIVNIDRGMAQLVLQDKDIRALLHAMLFVE
                     LQVAEHFSCQDNALIDPLIHALHKQPNPLWLGDLGVGNATAAPLVCGCFSGVKLDRSF
                     FISQIEKMTFPLLVKHIRRYCDKIVVGGQENTRYLPALKTAGIWATQGTLFPSVALEE
                     VETLLLGRRVNTLRESN"
     gene            complement(768..1574)
                     /gene="sapF"
                     /locus_tag="OPY25_004339"
     CDS             complement(768..1574)
                     /gene="sapF"
                     /locus_tag="OPY25_004339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HCS0929784.1"
                     /translation="MVETLLEVRNLSKTFRYRTGWFRRQTVDAVKPLSFTLRERQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHYGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTVLEPEQRRKQIVETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGVVVERGSTADVLASPLHELTRRLIAGHFGEALTADAWRKDR"
     gene            complement(1576..2568)
                     /gene="sapD"
                     /locus_tag="OPY25_004340"
     CDS             complement(1576..2568)
                     /gene="sapD"
                     /locus_tag="OPY25_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HCS0929785.1"
                     /translation="MPLLDIRNLTIEFKTSEGWVKAVDRVSMTLSEGEIRGLVGESGS
                     GKSLIAKAICGVAKDNWRVTADRMRFDDIDLLRLSSRERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRLGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     DGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKDLVTTPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIITPRLTGAKNHLYACHFPLNMERE"
     gene            complement(2568..3458)
                     /gene="sapC"
                     /locus_tag="OPY25_004341"
     CDS             complement(2568..3458)
                     /gene="sapC"
                     /locus_tag="OPY25_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HCS0929786.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCI
                     FGGWIAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FIVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSH
                     AMFAVWLALLPQMVRSVYSMVHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLS
                     VLLVNLLGDGIRRAIIAGVE"
     gene            3593..3994
                     /locus_tag="OPY25_004342"
     CDS             3593..3994
                     /locus_tag="OPY25_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001543117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
                     /protein_id="HCS0929787.1"
                     /translation="MYTQMCISSYGVYTLLADTKLRKAPGKKRDQIKVISDAHGLNVR
                     LSTSGSITFFYRYRWNGNAAQLTIGDYPTISLSHARERRQYFRSWLTEGLDPRRQMVL
                     EKKKKTEALTVKEHTTTGRSFSTVRNLGQGH"
     gene            complement(4268..>4748)
                     /locus_tag="OPY25_004343"
     CDS             complement(4268..>4748)
                     /locus_tag="OPY25_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929788.1"
                     /translation="SAAILNIRGAAPGTATIGNGATNLAKDIIRVANIAYNISQVEQK
                     SGFLLVTGEKGFNKSACLHMLGQQISRVFSGKHLYPGVFISKDAASEFEKTISTHYKT
                     LSGHIDLQQYTNDVNCGAAVGIVARQQENLILDEITLSTFKKVYVRFLRYCKLTVTV"
BASE COUNT         1188 a         1169 c         1211 g         1180 t
ORIGIN      
        1 taaaagcgca ttatcaggga gttaagatca agtggagtgg tcacatgcgc tattttttta
       61 tggcagagcc gataagggca atggaggggg atttactggg tgtcgaaatc actacccatt
      121 ttgcatcgtc gcccgctcgt ccgctacacc ctgagtttgt tatctcgtca tgggacaatt
      181 cgcagaagcg ccgttttctg cttgatctgt tgcggacaat cgcggccaaa catggctggt
      241 ttctacgcca cggcctgttc tgtatcgtaa atatcgatcg gggtatggcg cagcttgtcc
      301 ttcaggacaa agatattcgc gcattactac acgccatgct atttgtggag ttgcaggtcg
      361 ctgaacattt ttcatgtcaa gataacgcct taatcgatcc tttaatacac gcgcttcata
      421 agcaacctaa tccattatgg ctgggcgacc tgggcgtagg gaacgcaacc gctgcgccat
      481 tagtttgcgg gtgttttagc ggcgtaaaac ttgatcgcag cttttttatc tcacaaattg
      541 aaaaaatgac gtttccgctg cttgtcaaac atatccggcg ttattgtgac aagatcgtgg
      601 tgggtggcca ggaaaacaca cgctatttgc cggcgttaaa aacggcaggc atttgggcaa
      661 cccagggcac gttatttcct tccgttgcgt tagaagaggt tgaaacattg ctgttgggcc
      721 gtcgcgtgaa caccctcaga gaatcgaact gagggtattt gtgtcgctta gcgatccttt
      781 cgccatgcgt cagcggtcag cgcctcgcca aaatggcctg cgattaaacg gcgggtaagc
      841 tcatgtagcg gagaggcgag cacatcggcg gtgctgccgc gttcaaccac taccccctga
      901 tgcatcacta atacctgatc gctaatatgt ttcatcatgc cgatatgctg cgtgacgtag
      961 atataggaga tgccttgttt ttcctgcaat tcaagcatca gattgatgag ctgcgagcgc
     1021 atggacatat caagcgaagc cagcgcttcg tccgcgataa tgacttttgg gcgtaaaatc
     1081 agcgcgcggg ccagacccag acgttgtttc tgtcccggcg ccagcatatg cgggtagtag
     1141 ctcacgtgat cgggcaatag ccccaccata cgcatcgtct cgacaatctg tttgcgccgc
     1201 tgttccggct ccagaacggt attaaggcgc agggggaagt caagaatctg tgaaatacgt
     1261 tgacgtggat tcagtgacgt tgaagggtcc tgaaaaatca ttcgaatacg ttggcttcga
     1321 aacgaatagt cgccgtaatg caggggatga tcgtcaataa gaagctcgcc gctggtgggt
     1381 tcaatcatgc cggccagcat ctttgccaac gtggatttgc cggaaccgtt ttcgccgata
     1441 atggccaggg tctgacgctc acgaagcgta aagcttaatg gtttcacggc gtcgacggtc
     1501 tggcggcgaa accatcctgt tcggtagcga aaggttttac tcaggttgcg cacttcaagc
     1561 agagtttcca ccatatcact ctctctccat attcagcgga aaatgacagg catagagatg
     1621 atttttcgcg ccggttaagc gtggcgtgat aatgcattct cgttgcgcgt aagggcagcg
     1681 cggccccaga cgacaaccta tcggtaactg ctccagtagc gggatcgcgc ccggcagcgt
     1741 attcagacgg cttttatgcg gcatcgcgct gccaaaatcc ggaatcgcac ggataagcgc
     1801 ctgcgtataa ggatgatgtg gtgtcgtcac cagatcttta cttggcgcgg tttctaccgt
     1861 ctggccgcag tataagacgt tgattttgtc agcccactga ctcagcattt gcaggtcgtg
     1921 gctaatcaac agaatggtgg tattactgtt ttgattcagt cgcgtcaaca ggcgaaaaat
     1981 ttgcgcctgc gtcgtcggtt ccattgagtt ggtgggttca tcagcgatca ggagtcgcgg
     2041 ttgattcgcc agcgcgatag cgatcataac tttctgacac tcgccatcgg ttagttcata
     2101 gggaaaactg cgcatcgcgt ctttatgatc tttaattccc acccggtgca gtaattcaat
     2161 tgcacgccgt ttacgccagc ctaaacgctg ccaccagcgg cctttatagg tccaggcggg
     2221 aatattttgc attaactggc ggccgacgcg ttcggaagga tcaaggcacg actgcggctc
     2281 ctggaagatc atcgacacat tatgcccgac cagcttacgc cgttcacgag aggagaggcg
     2341 cagcagatcg atatcatcaa aacgcatacg gtcggcagtg actcgccagt tgtctttcgc
     2401 gacgccgcaa atagctttag caatcaagct ctttccggaa cccgattcac ctaccaggcc
     2461 gcgaatttca ccttcgctta atgtcatact gacgcgatcg accgctttta cccaaccttc
     2521 gctggtttta aattcaatgg tgagattgcg gatatccagt aacggcatta ttccaccccc
     2581 gcaataatcg cacgacgaat cccatctccg agcaggttta ccagtaaaac actgagcgtt
     2641 atcgccgcgc cgggtagcat aacggtccac ggcgcgacat agattaactc cagcgcatcc
     2701 cccaacatgg cgccccattc aggagaggga agctgcgcgc cgagatctaa aaatcccagc
     2761 gcggcgatgt ccagaatcgc catcgacagc gcccgggtaa tttcggtgac cagaccggcg
     2821 gtaatattcg gtaaaatggc gaaccacaga atattcagtg ttgtcgcgcc atccagacgg
     2881 gcagcaatga cgtactcttt ttccagttca tcatgcacca tgctatagac ggaacgtacc
     2941 atttgcggca acagggccag ccagacggca aacatcgcgt gtgacagatg tgggccggca
     3001 aatgccacaa cgataatcgc cagcaagagc gaagggatgg aaagcagcgt gtccagaata
     3061 tggttcagta cggcagagcg taaaccgtgg gtcgcgcctg ccactacgcc gaggactaat
     3121 ccacatagcg tagccgccag cgttacgata aacgcgccgc cgaccgtggg cgccgcgccg
     3181 cttaacaggc ggctcagcac atcgcgcccc agatcgtcag tccccagaaa aaaggagact
     3241 tcgccatagc gtgaccagga gggtggcagt agctgatagc ccagaaattg ctgatcgata
     3301 ccatagggcg cgatccagcc gccaaaaata cacagcaacg ccagaccggc gcatccatac
     3361 agacccacca tcgcaggcgc gtcgctataa aatttacgcc aggcagtgcg cagggtgcct
     3421 ggcgggcgct tttcgctgta gacgctatcg taaggcatat ttactcgttt tatttttgtt
     3481 taccatgctt tatgtctttt gaaattttca agcactatca attggttatg gattgtaagc
     3541 gtctcaattt tgtgtacttt gcattaatgt gaaggttatc aatttatgca aaatgtatac
     3601 acagatgtgt atatcctctt atggagtgta cacattgctt gccgatacaa aattaagaaa
     3661 ggctcctggc aaaaaaagag accaaatcaa ggtcatctca gacgctcatg gtctcaatgt
     3721 caggctctct acatccggca gtataacatt cttttaccga tacagatgga acgggaacgc
     3781 tgctcaactg acgattggcg attatccaac catatcacta tctcatgcca gggaacgccg
     3841 tcagtacttt agatcatggt taactgaggg actcgatcct cgtcgccaga tggtgctgga
     3901 gaagaagaaa aaaacagaag cgttaaccgt aaaagaacat acgactactg ggagaagttt
     3961 tagcactgta cggaatttgg gccagggtca ttaagaccga cagtggcgtc tggcactagt
     4021 ttgaagtatg gcgcgatcag gatgttgcag tatttgtaga agcggcgcgc ggcggcatcc
     4081 ggggaatagt ccggcttaaa gtatctggcg gagtttgtgt tcagttgcgg cattagtctt
     4141 tgggaggttc acaataagac agatcggaat actccggcat gaggtgttgc gtcttaaact
     4201 gctgcagcgg gtcagcaggg ggaatgatat ttattagctc agatgtgagc tgacagttac
     4261 cgattattta tacagtaact gtcagtttac aatatcgtaa aaacctaaca tagacctttt
     4321 taaacgtact taatgtgatc tcatctagta tgaggttttc ttgctgccgt gcaacaatac
     4381 ctacagctgc tccgcaattt acatcattag tgtattgttg cagatcaatg tgacccgaaa
     4441 gagttttata atgagtgctg attgtttttt caaattcgga cgctgcgtct ttacttataa
     4501 aaacaccagg atataagtgc ttcccagaaa aaactctgga tatttgttgt cccagcatat
     4561 gcaggcaagc agatttgttg aagcctttct ctcccgttac taacaagaaa ccactttttt
     4621 gctcaacctg tgaaatatta taagcaatat tagctaccct aataatatct ttggctaggt
     4681 tagttgcgcc atttccgata gtggcagtgc cgggggctgc ccctctaata ttgaggatcg
     4741 cggcagaa
//
LOCUS       DAJVKX010000214         4583 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.214, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000214 DAJVKX010000000
VERSION     DAJVKX010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4583
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.214"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            98..2898
                     /gene="misL"
                     /locus_tag="OPY25_004344"
                     /pseudo
     CDS             98..2898
                     /gene="misL"
                     /locus_tag="OPY25_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462656.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="intestinal colonization autotransporter adhesin
                     MisL"
     gene            complement(2993..3457)
                     /locus_tag="OPY25_004345"
     CDS             complement(2993..3457)
                     /locus_tag="OPY25_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929789.1"
                     /translation="MLACLTLLFLGVGLGHLFHLYTEKNRDPEKCTAPVIVFYNNTQA
                     NLTLDFMYSLKKRTGVVSISGTYYVDNKMSGVIRRDVSYVWSENKDSTHFISTDINKV
                     TRDETLSDAVIETVLPDFYVYPGKSISYTILTQGHRGFMFTIGKRPIFFCTH"
     gene            complement(3468..4324)
                     /locus_tag="OPY25_004346"
                     /pseudo
     CDS             complement(3468..4324)
                     /locus_tag="OPY25_004346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462658.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(4377..4490)
                     /locus_tag="OPY25_004347"
     CDS             complement(4377..4490)
                     /locus_tag="OPY25_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929790.1"
                     /translation="MIFSPQYKTGGLTNKKTKRTFTPESAIMRKAVSTLTC"
BASE COUNT         1218 a         1119 c         1141 g         1105 t
ORIGIN      
        1 aaataatatc aaatatttta tagatccgtt tccattttta ttatttccat attattgcga
       61 tgtggaagac gctttacgcc ataatgcagg aggcagaatg ccaactcccc aaaattactc
      121 attcatcgcc atagcggtat cagcagcatt agcctctatg gtatttccct cccaggcggc
      181 ctgggttgac gttgatagtc tgccatccag tgggctggtc agccagctgc cgccggaatt
      241 acaggctatt attcccgctc aggccagtac cggtttcacc aaagtcggta ccatgcccaa
      301 ctacgtttat cagtggaaca ccggcaccat cccggtttat ggcaatggcc tcacgcttaa
      361 tgggccgggt gcggaggcgt ttgaacacac tgtcacggtt attcagaaca gcgggacggg
      421 aagtccgggc gtgatttttg gcaacgacct gaccattcgg acgcagtcgg cgaatgccgc
      481 gaataatggt agagacgtcg atggcatccg tactcacggc gcaaatactc cggataaccc
      541 ggtatttatt attaccggtg accgtaccaa catctacgtg gatggtcagg atggtgacgg
      601 tattaacgcc ggatataact cactgggcca gggttggacc ggatcggcca atatttacgt
      661 cggcgacgat ctgtatatca aaacgaccgg tagccaggga cgtggaatta cagctaacgc
      721 catgcgggat gcgtcacgtg ccaaaaatac gattgtcgtc ggcaatcgtg tgcacatata
      781 gttactaccg gcgacagttc ggaggggctg cgtaccggac aaagcggttc gttgattcgt
      841 ctgggtgacg atgcaaccat cgaaacctcc ggcgcatcct caacggggat ttacgcagca
      901 tcctcctcca gaaccgagct tagcaacaac actactatta cggtgaacgg tgccagcgca
      961 cacgcggtat atgcaactaa cgctaccgtt aatttgggag agaatgccac tattagcgtt
     1021 aacagcgcca gtaaggctgc atcctatagt aaagcccctg ccggtttata cgccctctcc
     1081 cgaggcgcca ttaatctggc aggcggtgcg gctattacta tggcgggcga taacagtagc
     1141 gaaagttacg ccatcagcac ggaaactggc ggcattgttg acggttcttc aggaggtcgt
     1201 ttcgtcatcg acggtgatat tcgtgctgct ggcgccaccg ctgccagcgg tacgctaccg
     1261 cagcagaaca gtacgattaa gctcaatatg acggacaact cgcgatggga cggggcgtcg
     1321 tacatcacca gcgctacggc gggcacaggc gttatctctg tacaaatgag cgatgcgacc
     1381 tggaatatga ccagcagctc aacgctcact gacctgacgc tgaatagtgg cgcaatcatt
     1441 aacttcagcc atgaagatgg cgaaccatgg caaacgctca ccatcaatga agattatgta
     1501 ggcaacggcg gtaagctggt ctttaatact gtgctcaacg atgatgattc cgaaacggac
     1561 aggctgcagg ttctcggcaa tacttcaggc aacacatttg ttgcagtaaa taatattgga
     1621 ggagccgggg ctcaaaccgt tgaaggtatt gaaattgtta acgttgctgg caattccaac
     1681 ggtactttcg aaaaagcaag tcgtattgtt gccggagcct atgactacaa cgtggtgcag
     1741 aaaggtaaaa actggtatct gaccagctac attgagccgg acgaaccgat tattcctgat
     1801 ccggtagacc ctgttattcc tgaccctgtc attcccgatc cggtagaccc tgatccagta
     1861 gacccggtca tccctgatcc ggtcattcct gacataggac aatctgacac accgccgata
     1921 acagaacatc agttccgtcc ggaagtgggc agctatcttg ccaacaacta tgcggcaaat
     1981 acgctgttca tgacgcgtct ccatgaccgt ctgggtgaaa cccagtacac cgacatgctg
     2041 acgggtgaga agaaggtcac cagcctgtgg atgcgtaacg tcggcgccca tactcgcttc
     2101 aacgatggca gcgggcagct aaaaacccgc atcaacagct atgtgttaca actgggaggc
     2161 gatctggcac agtggagcac tgacagtctt gaccgttggc atattggtgc aatggcaggt
     2221 tatgccaaca gccagaaccg cacgcagtcg tccgtgagtg actatcattc ccgtggtcaa
     2281 gtcaccggtt acagcgtcgg cctttacggc acctggtatg ctaacaatat cgatcggtct
     2341 ggggcttatg tggatacctg gatgctgtac aactggtttg ataacaaggt catgggtcag
     2401 gatcaggccg ctgagaaata taaatccaaa ggaattaccg cctcggttga agccggttac
     2461 agtttcaggt taggtgaaag cgcgcatcaa agctactggt tgcagcccaa agcgcaggtg
     2521 gtatggatgg gcgtgcaggc taacgaccat cgcgaagcca atggtaccct cgtcaaggat
     2581 gataccgccg gtaatctgct aacccgcatg ggcgtaaaag cctatattaa cggccacaat
     2641 gctattgatg acaataaatc tcgagagttc cagccattcg tggaagcgaa ctggatccat
     2701 aatacgcagc ctgccagcgt gaagatggac gatgtcagca gcgatatgcg tggtacgaaa
     2761 aatattggtg aactgaaagt gggtattgaa ggacaaatta ccccgcgcct gaacgtatgg
     2821 ggtaacgtgg cgcaacaggt aggtgaccag ggctatagta atacccaagg cctactgggg
     2881 gttaaataca gtttctgatt caggtaacaa cagagccgct gatcttcagc ggcttttacc
     2941 cggaagcgct ttcatttggc tgatacgttc catgaacggc tcccaaaacc gcttaatgtg
     3001 tacagaaaaa tatcgggcgt ttcccgatgg tgaacataaa gccacgatga ccctgagtca
     3061 ggatggtgta actgatactt ttccctggat agacataaaa atcgggtaaa accgtctcga
     3121 taaccgcatc ggacagtgtt tcgtcacgcg tgactttgtt gatatccgtc gatataaaat
     3181 gggtgctgtc tttattttca ctccatacat aggaaacatc acggcggatc acgccgctca
     3241 ttttattatc gacgtaatac gttccgctga tggaaaccac tccagtgcgt tttttcagcg
     3301 aatacataaa gtccagcgtc aggttagcct gagtgttgtt ataaaacaca atcacaggcg
     3361 ccgtacattt ctctggatcc cggttctttt ccgtatataa atgaaaaaga tgcccaagcc
     3421 ctacacccag aaacagtagc gtcaggcagg ctaacatcag tgccttttta cccatgtgtc
     3481 accccgcgga aaaaaagcgt cacgcagcct gtatcaccgc gcgttttata aggttgctga
     3541 caaatcaatg ccgtaaccgc tggggtgcga ctgctggaag ggaaatagac ccatgggtat
     3601 ttctgacaat ccataccggt ttttagaatc attaacttat agcctgcaaa gcggctaccg
     3661 ctttcgatat cttcattccg cgagaaaaaa tgacagccct gagttgtttc aaccagcgtg
     3721 tagcgatcat aaaaatcctt atcaggaacg gtttgccagc tgatagtgcc aagcaaaata
     3781 ccgacagcaa atgtcccggt catccaaagt acaggtacat aatgtttaaa ccaacgccct
     3841 gacatacgcg gtggcgcctc accctttttt ctattgtctg agcgaagtct ttgcggatgg
     3901 tcatgaggct cacaccaggc tcaatctgaa agcctctacg cggaaccgtg attatcagcg
     3961 tatcttcatt ttcgccaacg gtacgtaatc cgcggcgaat aatggagata ttctgataaa
     4021 gcgtatttgc cgacaccacc atgccgtctt cttcctatac tttttgaaag aatgtttgtt
     4081 gtgagacgac ggagggggcg ttttccagca gaaggcgcaa gcagcggctg gcgggcgttg
     4141 tcagaataat gttgagatct ggcctcgata atgacgccag gcgattcatt tctggattaa
     4201 attcaatatt atcgttaatt atccataaca tcgcattgtt accatgccaa aacataacgt
     4261 agttggagag ggttaataga caccactgag tatagtctga tgctgtggct gcgtagcagg
     4321 acatggattg tcccctgcac ataccgatca tatagaagag cgagaggcat aagacattaa
     4381 caggtaagcg tagacaccgc ttttctcatt atagcagact caggggtgaa agtacgtttg
     4441 gttttcttgt tcgttaagcc tcctgttttg tattgaggtg agaatatcac ctttaatcaa
     4501 gtagccaaat ttactgtgcc actacgcttt aatatctcat atataaatca tgagaaaata
     4561 tatcctgaaa atctatatca tat
//
LOCUS       DAJVKX010000215         4474 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.215, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000215 DAJVKX010000000
VERSION     DAJVKX010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4474
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.215"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..710)
                     /gene="cysH"
                     /locus_tag="OPY25_004348"
     CDS             complement(<1..710)
                     /gene="cysH"
                     /locus_tag="OPY25_004348"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HCS0929791.1"
                     /translation="MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENL
                     PGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLK
                     VYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWAQGYLSVGDTHTT
                     RKWEPGMAEEETRFFGLKR"
     gene            complement(786..2498)
                     /gene="cysI"
                     /locus_tag="OPY25_004349"
     CDS             complement(786..2498)
                     /gene="cysI"
                     /locus_tag="OPY25_004349"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HCS0929792.1"
                     /translation="MSEKYPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKF
                     AADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESELHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGITFEPI
                     RPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRI
                     TANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERF
                     LPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGN
                     RIGSRIPRMYQENITEPDIQASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DFWE"
     gene            complement(2498..4297)
                     /gene="cysJ"
                     /locus_tag="OPY25_004350"
     CDS             complement(2498..4297)
                     /gene="cysJ"
                     /locus_tag="OPY25_004350"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HCS0929793.1"
                     /translation="MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGFFWGVL
                     NPRSGAVAVTPAPDGKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYK
                     FKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRACVVDVLKSRAPVAVPSQSV
                     ATGAVNDIHTSPYTKDAPLTATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVMVDGKTLPLAEALEWHFELTVNTANIVENYAT
                     LTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRPLTPRLYSIAS
                     AQAEVESEVHITVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPAN
                     PQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GLLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKAL
                     LEVIAEFGGMDLESADEYLSELRVERRYQRDVY"
BASE COUNT          928 a         1329 c         1206 g         1011 t
ORIGIN      
        1 cgtttcagtc cgaagaagcg tgtctcttct tccgccatac ccggctccca tttgcgggtg
       61 gtgtgcgtat cgcccaccga cagatagccc tgagcccaca gcggatggta tttcagaccg
      121 tgcttttgca gatactggta aaccgtgcgg ttatcccagt cgataatcgg tagcacttta
      181 aacacgccgc gctggatagc gagaacgggt aaatgcgcgc ggctaccgga ctgctcgcga
      241 cgcagacccg caaaccaggt ctgcgcgttt aactctttga gcgcccggtt catcggctcg
      301 actttgttga tctcattgta tttctcaatg ccctcaacgc cctgctccca cagcttgccg
      361 tagcgcgctt cctgccaggc cggactttcg cccgcgcggt aaactttcag gttgagtttg
      421 agtttgtccg ttagctcatc aataaactga taggtttccg ggaacaaata gccggtatcg
      481 gtgaggatca ccgggatatc cgggcgaatc tggttcacca ggtgcaggct caccgccgcc
      541 tggataccaa agcttgagga gagcacgtat tcgccgggca gattttccag cgcccaagcc
      601 acgcgttctt cggcagtcag cgtttccagt tgagcgttgg tttccgccaa cgccagtacg
      661 cgatcgactt ttggcagttc attcaatgcg ttgagatcga gttgggacat aagttcctca
      721 ctgtttgcct tgcctgatgg cgctgtgctt atcaggccta cacagacgcc atccggcaat
      781 tcaggttatt cccagaaatc acgcgcggga tcgagcaccg ggcgaatgat gcccgcacgc
      841 accgtaaagt cgccgaagcc ttcacccgct tcacgctctt tcgcccagcg cccaatcagt
      901 tcatccagcg aagcctgaat atccggctcg gtgatatttt cttgatacat ccgtggaata
      961 cgactcccga tgcggttgcc gccaagatgc aggttataac gaccaggcgc tttccctact
     1021 aagccaattt ccgccagcat cgcgcgacca cagccgttcg ggcagccggt cacgcgcatc
     1081 acgatatgct catcaggaat gccgtgtttt tccagaatcg cttccacttt gtcagtaaac
     1141 gacggtagga aacgctcggc ttccgccatc gccagcgggc aggtcgggaa cgacacgcag
     1201 gccattgagt tttcacgctg cgcgctcacc gcattcatca gcccatgatc gcgcgccagt
     1261 ttctcgatct tcgctttctg gctttccggc acgctggcaa taatcaggtt ctggttagcg
     1321 gtaatacgga actcgccctg atgaatcttc gcgatctcca gcaggccggt tttcagcgga
     1381 cgccccggat agtccaggat acgaccgttt tcgataaaca gcgtcaggtg ccatttatca
     1441 tcaatgcctt tcacccagcc aatcctgtcg ccacgcccgg taaattcata cggacgaatg
     1501 ggttcaaatg tgatccccgc gcgacgctcg acttccgctt taaacgtctc cagtcccaca
     1561 cgctcaaggg tgtatttggt tttggcgttt ttacggtcgg tacggttacc ccagtcgcgc
     1621 tgcgtagtca ccaccgcttc cgccaccgcc agggtgtgct ccagcggcag atagccaaac
     1681 tcgctcgcgg tacgagcgta ggttttctta ttaccgtgct caatagacag accgccgccc
     1741 accagcaggt taaagccgac cagcttgccg ttctcggcaa tcgccacgaa gttcatgtcg
     1801 ttggcgtgca gatcgatatc gttttgcggc gggatcacta ccgtggtttt gaacttacgc
     1861 ggcagatagg tctgtccgag gatcggctct tcatcggtgg tcgccacctt ctcctgatcg
     1921 agccagatct ccgcatacgc acgagtgcgc ggcagcagat gttcggagat cttcttcgcc
     1981 cattcgtagg cttccgcgtg cagctcggac tcatacgggt tagaggtaca cagcacgtta
     2041 cggttcatat cgttggcggt cgccagcgcg tccagcccca ccgaatgcag catctggtgc
     2101 accggcttaa cgttcttctt cagaataccg tggaactgga aggtctgacg gttggtcaga
     2161 cggatactgc cataaatcgt gttatccgcc gcgaatttat cgatcgcctg ccattgcgtc
     2221 gtagtaatca ccccgcccgg caggcggcag cgcagcagca tggcgtggcg cggctccagc
     2281 ttctgcgccg cacgctcggc gcgaatatcg cggtcatcct gctgatacat gccatgaaag
     2341 cgtattagca ggaagttgtc gcctttaaaa ccgccggtga gaccgtcgtt cagatcttcc
     2401 gcaatggtac cgcgcaggta gttgctttcc agcttcatgc gctcggcatc ggacagttta
     2461 ccttcgacca ccagtgggcc tggatatttt tcgctcatta gtagacatct cgctgataac
     2521 ggcgctctac gcgcagctca cttaaatatt catctgccga ttcgaggtcc ataccgccga
     2581 attcagcgat cacttccagc aatgcttttt cgacatctgc ggccatgcgc ctggcgtcgc
     2641 cgcagacata aatgtgggcg ccatcattga tccagcgcca cagctccgcg ccctgttcac
     2701 gcagcttgtc ttgtacgtaa attttttctt tttgatcgcg ggaccaggcg agatcgatac
     2761 ggcttaacag tccctctttc acgtagcgct gccactccac ctgatagagg aaatcttcgg
     2821 taaagtgcgg gttgccgaag aacagccagt tcttgccttc cgcgccatcg gcggcacgct
     2881 gttgcataaa ggcgcggaac ggcgcgatgc cggtgccggg gccaatcatg atcaccggcg
     2941 tttgcgggtt cgctggcagg cggaagttat cgttatgctc aataaagacg cgaacttcgc
     3001 cctcttcttc cacgcggtcg gcgaggaagc tggaagcgcc acccgcgcgg gcgcggcctt
     3061 cgatatcata gcgaaccacg ccaacggtga tatgcacttc actctccact tcagcctgtg
     3121 cggaggcgat ggagtacaga cgcggcgtca gcgggcgcag caggtcgatt agcgcctgag
     3181 catccagctg cgccggagag aaacgcacca tatcaacgat cggcgtggtc gcggcgtaat
     3241 gctggagctg cgctttgtca cccactaatg gcaacagcga ctcactgcgc gtcagggtcg
     3301 cgtagttctc aacaatgttg gcggtattca ccgtcagctc gaagtgccac tccagcgctt
     3361 cggcgagcgg cagggtttta ccatcaacca tcaccggctc atcgcctttc agccacagca
     3421 actcaaccag ttccttcacc agagccggat cgttctgata ccagacgccc agcgcatcgc
     3481 ccggctggta acgcagaccg gagtcgccta aatcaatctc aatatgacga acgtcttttt
     3541 ccgagttgcg accggtgatt ttctgattca cggagagggt cgcggtcagc ggcgcgtctt
     3601 tggtataggg gctggtgtgg atgtcgttta ccgcgccagt agcgacggat tgcgaaggta
     3661 ccgcgacagg tgcacgggac ttcagaacat caaccacgca ggcgcgccat tcgctggcag
     3721 ctgcctgata ttcaacgtca gcatcgacac ggtcgagcag acgctcaccg cccagttccg
     3781 ccagtttgct gtcgaaatct tttccggact ggcagaaaaa ttcataagag gtgtcgccga
     3841 ggctaaacac ggcaaaagcg gtgttttcta gtttcggcgc ttttttcgag aacaggaact
     3901 tatgcagcgc gacagcctct tccggcggct cgccttctcc ctgggtggac gtcactatca
     3961 ccaacagttt ttcactggca atctgtttga atttgtagtc gccggcgttc accagagtca
     4021 cattaaggtt ggccgccagc agatcatcac gcagcgcttc cgccacacga cgcgcattgc
     4081 cggtttgcga agcggagata agcgtaactc ccggcatctt cccatcagga gcaggcgtga
     4141 cggcaacagc gcctgagcgc gggttcagta cgccccaaaa aaagccggag acccaggcaa
     4201 gctgttcggg agtaaggtcg gttgtcgcgg cctgaaggcg cgccagttgc tccggattaa
     4261 gcggaagcaa cccagtcagt ggagccggtg tcgtcatgcg tcgttatgtt ccagtaagca
     4321 aagcggatct atacacaaaa tcattcaagt tcgctgtagc ccagactgta agctgatcgc
     4381 gccccaggag cgtacataaa tacgtgactg gggcgagtaa acgcagtcaa cacaaatgcg
     4441 gcttgaagga tgaagtgtat aagcgataaa tccc
//
LOCUS       DAJVKX010000216         4406 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.216, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000216 DAJVKX010000000
VERSION     DAJVKX010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4406
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.216"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..289
                     /locus_tag="OPY25_004351"
     CDS             <1..289
                     /locus_tag="OPY25_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929794.1"
                     /translation="TRKAIQAGGITLGHTYHAKDYGPMLRSAGFTAIGTYEMPREGDV
                     IIIQPYAGGNPSGHMAIYDGAEWYSDFKQRDMWAGPGYRAARPSYTIYRKN"
     gene            289..807
                     /locus_tag="OPY25_004352"
     CDS             289..807
                     /locus_tag="OPY25_004352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HCS0929795.1"
                     /translation="MKTFSLVALILLLCSCSAPHHDSTQAVKQFYTSWMTTFMNDVNT
                     PDDTTALMQRYVAKEVIHRLALIQSLYEQEIVGADYFMYAQDYAPEWIPQLRVGKAHP
                     FLGGEKVDVLLATESTPIHLEVYTRWEEGRWKIYRVRDADKDYEQPIYDAGAITQAEA
                     WSAKVAPEYEKH"
     gene            complement(874..1530)
                     /locus_tag="OPY25_004353"
     CDS             complement(874..1530)
                     /locus_tag="OPY25_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCS0929796.1"
                     /translation="MPTNTLDKIRHSLSCVAVLFGLFGIFVFASFSPSYAWLYLGGLA
                     APFIYSIVFVYAIAAWSIYSKYYPFLSLGRLSFVECFVPALALVCLTVLYNVFSGPEP
                     WMAELSRQFFLHKFLNTLVMCFLAPVAEEIIFRGFLLNSSIGWGRYSRVSGIIITSLA
                     FAFMHTQYLFAVTFVYLFVFSSILCVVRMRSRGLMIPITLHILNNAWVIFGLLFSATE
                     "
     gene            complement(1628..2842)
                     /gene="fabB"
                     /locus_tag="OPY25_004354"
     CDS             complement(1628..2842)
                     /gene="fabB"
                     /locus_tag="OPY25_004354"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HCS0929797.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDAGM
                     RSQVWGNVKLDTTGLIDRKVVRFMSDASIYAYLSMEQAVADAGLAPEVYQNNPRVGLI
                     AGSGGGSPKFQVFGADAMRSPRGLKAVGPYVVTKAMASGVSACLATPFKIYGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMQMAMHGVDTPIDYLNSHGTSTPVGDVKELGAIREVFGDNSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTERELTTVMSNSFGF
                     GGTNATLVMRKL"
     gene            3002..>4406
                     /gene="mnmC"
                     /locus_tag="OPY25_004355"
     CDS             3002..>4406
                     /gene="mnmC"
                     /locus_tag="OPY25_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HCS0929798.1"
                     /translation="MKQYAIQPATLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNRLAERFPVHSHPLFIVAESGFGTGLNFLTLWQAFDSFRSAHPQATLQRLHFISFEK
                     FPLTRDDLALAHQHWPELAPWAEQLQAQWPLPLPGCHRLLLDRGRVTLDLWFGDINEL
                     TDQLDATLNQTVDAWFLDGFAPAKNPDMWTPNLFNAMARLARPGATLATFTSAGFVRR
                     GLQEAGFTMQKHKGFGRKREMLCGVMEQHLMPTLSAPWFYCSGSEKRETAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADDQPAQGASGNRQGALYPLLSKHDAAINRFFPTAFTFAR
                     RLYDALPVSFDHAWCGVTQLGWDEKSQQKIAQMLSLALPAGLASALNAEEAEQAVGVT
                     TRCGGITYPAGGWLCPEQLTRAVIALATEQGLQTRFRHTLTSLVAQESRWQLRFTSGE
                     TASHETVVLANGHQINRF"
BASE COUNT         1108 a         1195 c         1124 g          979 t
ORIGIN      
        1 tacccgaaag gcaattcagg cgggcggtat cacgctgggg catacatatc atgcgaaaga
       61 ttatggccca atgttaagaa gcgccggatt caccgctatt ggtacctatg aaatgccgcg
      121 cgagggtgac gtcatcatta ttcaacctta cgctggcgga aacccgagcg gtcacatggc
      181 gatatacgat ggcgcagagt ggtattcaga ttttaaacaa cgcgatatgt gggccggccc
      241 gggctaccgg gcagccaggc cctcatatac catctacagg aagaattaat gaaaacgttc
      301 tcccttgtcg cgcttatcct gttgctttgt agttgctctg cgcctcatca cgacagtacg
      361 caggccgtga agcagttcta tacctcatgg atgacgacgt tcatgaacga tgtgaatacc
      421 cctgacgaca ccaccgcctt aatgcaacgt tacgttgcta aagaggttat tcatcgcctg
      481 gcgctaatac agtcccttta tgaacaggag attgtagggg cagattattt tatgtatgcg
      541 caggactatg cgccagagtg gattccacag ttacgggttg ggaaggcaca ccctttcctc
      601 ggcggagaaa aagtggatgt tctgttggct acagagtcaa cgcccatcca cctggaagtt
      661 tatacccgtt gggaagaggg acgctggaaa atttaccgcg ttcgggatgc tgataaggat
      721 tatgaacagc cgatttatga cgcaggcgcc atcacccagg ctgaggcctg gtcagcaaaa
      781 gtcgcgccgg aatatgagaa gcattaaaaa agggaaccgc catcgttctc ttgttcgtac
      841 cggagaggtt aaagagccta tttcatcagg ctcttattcc gtcgctgaaa acagcaagcc
      901 gaaaataacc caggcattat ttaaaatatg aagtgttatc ggtatcatta gtccacggct
      961 tctcattcga acaacgcata atatcgatga aaaaacaaac agataaacaa aagtcaccgc
     1021 aaagagatat tgtgtatgca taaatgcaaa agcgagtgaa gtaataataa taccggaaac
     1081 tcttgagtat cgaccccaac cgatactgct gtttaataaa aaccctctga atataatttc
     1141 ctccgccaca ggagccagaa agcacatcac cagcgtgtta agaaatttat gaagaaaaaa
     1201 ttgccttgat aactcggcca tccagggttc cgggccacta aaaacattgt agagaacggt
     1261 aaggcacacc agggccagcg ccggaacaaa acattccaca aatgataagc ggcccaatga
     1321 taaaaacgga taatactttg aataaatact ccaggcggca atcgcgtaga caaaaacaat
     1381 actatatata aaaggcgcag ccagacctcc caaataaagc caggcatagg aaggcgaaaa
     1441 tgaggcaaaa acaaaaatgc cgaacaaacc aaataaaaca gccacacaac tcaaactatg
     1501 cctaatttta tctaatgtat tagttggcat ttatataata tccatataat ttgttgttcc
     1561 ctgaatgaaa aaacaggtcg cattagcgac ctgtttcatt gttgatacta caacgtaata
     1621 gtcaggctta caacttacgc atcaccagcg tggcgttggt gccgccaaaa ccgaagctgt
     1681 tagacattac ggtagtcagt tcacgctcgg tcgtttcggt cacgatgttc aggcccgcag
     1741 cctgctcatc cagctcttcg atgttgatac tcggcgcgat aaaaccgtgc tccagcatta
     1801 gcagagagta gatggcttcc tgcacgccag ccgcgcccag cgagtggccg gtcatcgctt
     1861 tggttgcaga aattgccggg ctgttatcgc caaacacttc acggattgca ccgagttctt
     1921 tcacgtcgcc taccggcgtg gacgtaccgt gagagttcag gtagtcgatc ggcgtgtcta
     1981 cgccgtgcat cgccatctgc atgcaacgta ctgcgccttc gccagacgga gcaaccatgt
     2041 ctgcgccatc ggatgttgcg ccatagccga cgatttccgc atagatatgc gcgccgcgcg
     2101 ccagagcgtg ctccagctct tcgacaacaa ccataccgcc accgcccgcg atgacaaacc
     2161 catcacggtg cgcatcatag gtacgggacg ctttttcagg cgtatcgtta tatttggtgg
     2221 acagtgcccc catcgcatcg aactcacagg ccatttccca gcacagctct tcgccgccgc
     2281 cagcaaaaac gatgtcctgt ttgcccagtt ggatctgttc aaccgcattg ccgatacagt
     2341 gtgcggaggt cgcgcaagcg gagctaatgg agtagttcac gccataaatt ttaaacggcg
     2401 tagcgaggca ggcggaaacg ccggatgcca ttgctttcgt caccacatac gggcccacag
     2461 ctttcagacc acgcgggcta cgcatggcgt ctgcgccaaa gacctggaat ttcggggagc
     2521 cgccgccgga acctgcaatc aggccgacac gcgggttatt ctgatagact tccggcgcca
     2581 gaccggcgtc ggccactgcc tgctccatag acagataagc atagatggag gcgtcgctca
     2641 taaagcgcac gactttgcgg tcaatgaggc cagtggtatc cagttttacg ttgccccata
     2701 cctggctacg catgccggcg tccttcagct cctgagagaa agtgatccct gaacgtcctt
     2761 cacgcagaga tgccaggact tcctgctggt tattaccgat gctggaaacg atgcccaggc
     2821 cagtaatcac tgcacgtttc attcaatacc tctgtaattc gcactatttt taagtttcga
     2881 ttggcacaat agcgtacact tgtacgccga acaagtccga tcagccattt agtacggaaa
     2941 tttgcgccat caggcacaca tcgttaagat cgcgataccg cccgtcagac gagtaactta
     3001 cgtgaaacaa tacgccatac aacccgccac actcgaattt aacgctgagg gtacacctgt
     3061 ttcccgagat tttgatgatg tctatttttc taatgacaat ggactcgaag agacacgcta
     3121 cgtttttctt ggcggcaatc gtcttgcgga gcgatttccc gtacattcac atccattatt
     3181 tatagtcgcg gaaagcggtt ttggcaccgg actcaacttc ctgacgctgt ggcaggcgtt
     3241 tgacagcttt cgttctgcgc acccacaggc gacgctgcaa aggttacatt tcatcagctt
     3301 tgagaaattc ccgttaacgc gcgacgatct ggcgctggcg caccaacact ggccggagct
     3361 cgcgccctgg gcagagcagc tgcaggcgca atggccgctg ccgctcccgg ggtgccaccg
     3421 cctattgctg gatcggggtc gggtgacgct ggatttgtgg tttggcgata ttaatgagct
     3481 gaccgaccaa ctggacgcca cgctgaatca aacagtcgac gcctggttcc tcgacggttt
     3541 tgccccggcg aaaaatccgg atatgtggac gccaaacctg tttaacgcga tggcgcggct
     3601 ggcgcggccc ggcgcaacgc tggcgacgtt tacctcggcg ggtttcgtcc gtcggggatt
     3661 acaggaagcc ggttttacca tgcaaaaaca caaaggcttc ggacgtaaac gcgagatgct
     3721 ttgtggagtg atggaacaac acctcatgcc gaccctttcc gcgccctggt tttactgcag
     3781 cggaagcgaa aaacgtgaaa cggcgatcat tggcggcggc atcgccagcg cgctgttatc
     3841 actggcgtta ctgcgtcgcg gctggcaggt gacgctctat tgcgcagatg atcagcccgc
     3901 ccagggcgct tccggtaatc gacagggcgc gctttatccg ctccttagca aacatgacgc
     3961 cgccattaat cgctttttcc cgaccgcatt cacctttgcc cgtcgcctgt atgatgccct
     4021 gcccgtctct tttgatcatg cctggtgcgg cgtgacacag ctcggatggg atgagaaaag
     4081 ccagcagaaa attgcccaga tgctgtccct ggcgctgccc gccggactgg cctcggcgct
     4141 caatgccgaa gaggcggaac aggcggttgg cgtgacgaca cgctgcggag gaattaccta
     4201 tccggcaggc ggctggctgt gcccggaaca attaactcgc gcagtcatcg cactggcgac
     4261 tgaacagggt ttacaaacgc gctttcgcca tacgctcacg tcgctcgttg cgcaggagtc
     4321 gcgctggcaa ctgcgcttta cgtcaggtga aaccgccagc catgagactg tcgtcctggc
     4381 gaacggccat cagattaacc gttttg
//
LOCUS       DAJVKX010000217         4393 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.217, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000217 DAJVKX010000000
VERSION     DAJVKX010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4393
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.217"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            49..1119
                     /gene="aroF"
                     /locus_tag="OPY25_004356"
     CDS             49..1119
                     /gene="aroF"
                     /locus_tag="OPY25_004356"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HCS0929799.1"
                     /translation="MQKDALNNVRITDEQVLMTPEQLKAAFPLSLAQEAQIAQSRGII
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLKIARQLLVELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPHGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHKDLSGQLAVRVA"
     gene            1129..2250
                     /gene="tyrA"
                     /locus_tag="OPY25_004357"
     CDS             1129..2250
                     /gene="tyrA"
                     /locus_tag="OPY25_004357"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HCS0929800.1"
                     /translation="MVAELTALRDQIDDVDKALLNLLAKRLELVAKVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEAIGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQQDWPRARDIVADAGMVIVSVPIHVTEQVIA
                     QLPPLPSDCILVDLASVKSGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     QPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGDAIGLLEQG
                     DKQAFIDSFRKVEHWFGDYARRFQNESRVLLRQANDSRP"
     gene            2308..3216
                     /locus_tag="OPY25_004358"
     CDS             2308..3216
                     /locus_tag="OPY25_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="HCS0929801.1"
                     /translation="MTTPHLLFDYVGHLPECPTWSEDESALYWTDILEQEIYRYHPAS
                     GTHSVLAFPEEVGCFALREQGGFIVAMRHAIWLADKNGLLQRKVCDNPSNTKLARFND
                     GGTDGDGRFYAGTFWAPGDYNGALLMRIDHDLTAKVIQCGIQGHNGLAFSPDNQWMYT
                     SDTPNGVIYRTLLDKHGEPGKRELFRHFGEGEGLPDGAAMDSEGCYWSAMFDGWRVAR
                     FSPQGEQLEEYRLPVRCPTMVCFGGADMKTLFITTTRENMSAQEVADYPLSGAIFTLQ
                     VAVAGMKKSRFIERQAGSTGTTFSLG"
     gene            complement(3177..4337)
                     /gene="pheA"
                     /locus_tag="OPY25_004359"
     CDS             complement(3177..4337)
                     /gene="pheA"
                     /locus_tag="OPY25_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HCS0929802.1"
                     /translation="MTSENPLLALRDKISALDEELLALLAKRRALAIEVGQAKLLSHR
                     PVRDIDRERALLDRLIHLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNNTHPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFTDIFHQVETGQADYAVVPIEN
                     TNSGAINDVYDLLQHTSLSIVGEMTVTIDHCVLVSGATDLNTIETVYSHPQPFQQCSK
                     FLSRYPHWKIDYTESTSAAMEKVAQANSPRVAALGSEAGGMLHGLQVLERIAANQTQN
                     ITRFLVLARKAINVSDQVPAKTTLLIATGQQAGALVEALLVLRNHNLIMTKLESRPIH
                     GNPWEEMFYLDIQANLESQVMQSALKELGEITRSMKVLGCYPSENVVPVEPA"
BASE COUNT          974 a         1070 c         1289 g         1060 t
ORIGIN      
        1 ctcgtggagg atcaactatc gcaaacaaga aaagacagga tcgccatcat gcaaaaagac
       61 gcgctgaata acgtacgtat caccgatgaa caggtattaa tgacgccgga gcagcttaaa
      121 gcggcctttc cgttgagcct ggcgcaggaa gcgcagatag cgcagtcccg gggaatcatt
      181 tctgacatta ttgccgggcg cgatccgcgt ctgttggtgg tatgcggtcc ttgttctatt
      241 cacgatcctg aaaccgctct ggaatatgcc cgtcgattta aagcccttgc cgcagaggtc
      301 agcgatagcc tctatctggt aatgcgcgtc tattttgaaa agccgcggac taccgtcggc
      361 tggaaagggc tgattaacga tcctcacatg gatggctcat ttgatgtgga agccgggttg
      421 aaaatagcgc gtcagctact ggtggaactg gtgaatatgg ggttgccatt ggcgaccgaa
      481 gcgttggatc cgaacagccc gcaatacctg ggcgatctgt ttagctggtc ggcgataggc
      541 gcgcgcacaa ccgaatcgca aacccaccgc gaaatggcgt ctggtctttc tatgccggtc
      601 ggctttaaaa acggcacgga tggcagcctg gcgacagcga ttaacgccat gcgcgccgct
      661 gcgcaacctc atcgttttgt tggcattaac caggccggtc aggttgcgtt attgcaaacc
      721 cagggaaatc cgcatggcca tgtgattctg cgtggcggca aagcgccaaa ctatagcccg
      781 gcagatgtcg ctcagtgtga aaaagagatg gaacaggcgg ggctacgtcc ttcgctgatg
      841 gtagattgca gtcatggtaa ctccaataaa gattatcgcc gccagccagc cgttgccgaa
      901 tctgtggttg cgcagattaa agatggcaat cgttcaatca ttggcttaat gattgaaagt
      961 aatattcatg agggtaatca gtcttccgaa cagccgcgca gcgaaatgaa gtatggcgtt
     1021 tccgtcaccg atgcttgtat tagctgggag atgaccgatg ccctgttacg tgaaattcat
     1081 aaagatttga gcggccagct ggcggtgcgc gtcgcataag aggttgttat ggttgctgaa
     1141 ttgaccgcgt tacgcgatca aatagatgat gtcgataaag cgttgttgaa tttactggct
     1201 aagcgcctgg aactggttgc caaagtcggc gaggtgaaaa gccgttttgg cctgcctatt
     1261 tacgtgccgg agcgtgaggc ctctatgctg gcttcacgac gggcggaagc agaagcgatc
     1321 ggtgtcccgc ccgatctcat tgaagatgtc ctgcgccggg taatgcgtga atcttactcc
     1381 agcgaaaatg ataaggggtt caaaacgctt tgtccttctc tgcgtccggt cgtcattgtg
     1441 ggcggcggcg gacagatggg gcgtctgttt gaaaaaatgc tcacgctgtc gggctatcag
     1501 gtccgtattc tggaacaaca ggactggccg cgcgccaggg acattgtcgc cgatgccgga
     1561 atggtgatcg tcagcgtgcc gattcatgtt actgaacagg tcatagcgca actgccgccc
     1621 ctgccgtccg actgtattct ggtcgatctg gcatcggtga aaagcggtcc gttacaggca
     1681 atgttggcgg cccatgatgg ccccgtgctg ggcttgcacc cgatgtttgg cccggacagc
     1741 gggagcctgg cgaagcaggt ggtggtctgg tgtgatgggc gtcaaccgga agcgtatcag
     1801 tggttccttg agcaaatcca ggtgtggggc gcgcggttgc accgaattag cgctgtcgag
     1861 cacgatcaga acatggcttt tatccaggcg ctgcgccact ttgctacctt cgcttatggg
     1921 ctgcatctgg cggaagagaa cgtccagctt gagcagcttc tggcgctatc atcgccgatt
     1981 tatcgactgg agctggcgat ggtcgggcgt ctgttcgccc aggacccgca gctgtatgca
     2041 gacattatta tgtcgtcgga gcgcaatctg gcgcttatca agcgttacta taaacgtttt
     2101 ggcgatgcga tcgggttact ggaacagggt gataagcagg cttttatcga cagttttcgc
     2161 aaagttgaac actggtttgg cgattatgcc agacgcttcc agaatgaaag ccgtgtgtta
     2221 ttacgtcagg cgaatgacag ccgaccataa tgatgacatc tatactaaaa gccagctttg
     2281 ctggcttttt tcgtttaagg aaccgttatg actacgccgc accttttatt tgattatgtc
     2341 ggacatttac cagaatgccc cacatggagc gaggatgaaa gcgcgctgta ttggactgat
     2401 atcctggaac aggagatcta tcgttaccat ccggcgagtg ggacgcatag cgtgctggcg
     2461 tttccggaag aggtaggctg ttttgccttg cgtgagcagg gcggatttat tgtggccatg
     2521 cgtcatgcta tttggctggc cgataaaaat ggattattgc agcgtaaggt ttgcgacaat
     2581 ccctctaata cgaaactggc gcgtttcaac gatggcggca ctgatggcga tggccgtttt
     2641 tatgccggaa cgttctgggc gccgggtgac tataatggcg cgttgctgat gcggatcgat
     2701 catgacctga cggcaaaagt gatccagtgc ggtatccagg gacacaacgg cctggcgttc
     2761 agcccggaca accagtggat gtatacttcc gatacgccga atggcgtgat ataccgcacg
     2821 ttacttgata agcatggcga accgggcaag cgtgaacttt ttcgccattt tggcgaagga
     2881 gaaggacttc ccgacggcgc ggcgatggat agcgaagggt gctactggag cgcgatgttt
     2941 gacggctggc gcgtggcgcg tttctcaccg caaggagagc agctggaaga gtaccggttg
     3001 ccggtacgtt gtccgacgat ggtttgcttt ggcggcgcag atatgaaaac gctgtttatt
     3061 acaactacca gagaaaatat gtctgctcag gaagtggcgg attatccgct ctccggcgcc
     3121 atcttcaccc tgcaggtagc cgtcgcaggg atgaagaaaa gccgttttat tgaacgtcag
     3181 gcaggttcta ccggcacgac gttttcgctg ggatagcagc caagcacttt cattgagcgc
     3241 gtgatctcgc ccagctcttt tagcgcgctt tgcattacct gcgactccag gttcgcctga
     3301 atatcgagat aaaacatctc ttcccacgga ttgccgtgaa tggggcgcga ctccagtttc
     3361 gtcatgatga gattgtggtt acgcagcacc agcagcgctt cgaccagcgc gccagcttgc
     3421 tgcccggtgg cgattaacag agtggttttt gccggaacct gatcggaaac gttgatggct
     3481 ttgcgcgcca gtaccagaaa gcgggtgata ttctgtgtct ggtttgcggc gatgcgttcc
     3541 agcacctgta aaccgtgcaa catgccgcct gcctcgctgc cgagcgccgc gacgcgcgga
     3601 gagtttgcct gcgcgacttt ttccatcgct gccgacgtac tctcggtata gtcgattttc
     3661 cagtgcggat agcggctcaa aaatttactg cactgctgaa acggctgcgg atggctgtac
     3721 accgtttcga tggtattcag atccgtagcg ccggaaacca gcacgcagtg atcgatagtg
     3781 acggtcatct caccgacaat cgacagactg gtgtgttgca ataagtcgta cacatcgttg
     3841 atagcgccgg agttggtgtt ctctatcgga accacggcgt aatcggcctg gccggtttcg
     3901 acctgatgaa aaatatcggt gaattttgcg caaccgctct caataaattg ctcaaaatgg
     3961 cgtgcagcat actggcgcgc cgcgagatga gaataggagc ctttcggccc aagaaacgca
     4021 atacgtgccg aatgagggtg agtattattc agatgttgtt gcagcagcgc ctgctgagta
     4081 agcacggagt cttcaatgat aagctggaac agacgggtaa tgtagtgtgc gtcgagatgg
     4141 tgggctttac cgagatggat gagtctgtcc agcagcgcgc gttcacgatc gatatcccga
     4201 accggacgat gcgacagtag ttttgcttgt cccacttcaa tcgccagcgc gcgtcgtttt
     4261 gccagtaagg ccagtaactc ttcgtctaaa gcgctgattt tatctcgcag cgccagtaat
     4321 gggttttccg atgtcatagt gttgcctttt ttgttatcaa taaaaaaggc ctcccggtgg
     4381 gggaggcctt ctt
//
LOCUS       DAJVKX010000218         4301 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.218, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000218 DAJVKX010000000
VERSION     DAJVKX010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4301
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.218"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            171..647
                     /locus_tag="OPY25_004360"
     CDS             171..647
                     /locus_tag="OPY25_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929803.1"
                     /translation="MSKDEISYQILYRYSLEKLYSTLTRRVDNVLSFALVFLGVGVTI
                     NVGSPFILGPGIVGIAILKRVLRFGTRSTQADRQSRAWLKLFNTQHRFPSDKTLFLAF
                     TSLEQDASEVWSMLIGPAIVMTETALGKTPIEPLTAGEKLCAFLSGATKSQPAARN"
     gene            complement(1035..1454)
                     /locus_tag="OPY25_004361"
     CDS             complement(1035..1454)
                     /locus_tag="OPY25_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0929804.1"
                     /translation="MDIQITHQVTEFDKEELLAGLRSYNAQFVDFSKNGQLGVYCRNE
                     SGEMVGGLIADRKGPWLCIDYLWVSESARSRGLGSQLMEMAEKEGLRKGCVHGLVDTF
                     SFQALPFYEKQGHILQMSLPDFPKVGSQRHYLIKPDL"
     gene            1825..2091
                     /locus_tag="OPY25_004362"
     CDS             1825..2091
                     /locus_tag="OPY25_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929805.1"
                     /translation="MKFDNAWNQGVWYALRSATGRLSPQPFSVEDLPALGEECRRIMK
                     ITSAVYTSKKTLSERWFASAELLNLYLTKYGLSCLNCSRKKTTA"
     gene            2260..2400
                     /locus_tag="OPY25_004363"
     CDS             2260..2400
                     /locus_tag="OPY25_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460815.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929806.1"
                     /translation="MFRSTRTLPRNLQTYTEQASTEELHTDLNNMQSTGLYSIQQMVL
                     QL"
     gene            complement(2442..3646)
                     /locus_tag="OPY25_004364"
                     /pseudo
     CDS             complement(2442..3646)
                     /locus_tag="OPY25_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343613.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3716..4137
                     /locus_tag="OPY25_004365"
                     /pseudo
     CDS             3716..4137
                     /locus_tag="OPY25_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189081.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT         1158 a         1034 c          965 g         1144 t
ORIGIN      
        1 tggtgcagga gaaatgatat tcaaagcgat atcgactaaa agctcaaaat atttgcctgc
       61 tatttatatt ctatctaatt aatactctcc aggaagtgtg gcataattgc agaatctgtc
      121 aggattccgg gagcataccg gagcgtaatc gaaaaaccat ctggagatgt atgagcaagg
      181 atgaaatcag ttatcaaatt ctttaccggt actctctgga aaaactatac agtactctta
      241 ccagaagagt agataacgtg ctgtcattcg ccctcgtttt tctcggggtc ggcgtcacca
      301 taaacgtcgg gagtcccttt attctggggc caggcattgt gggtatcgcc atactaaaaa
      361 gagtactccg cttcggcacg cgctcaacac aggccgaccg gcagtcccgc gcctggctga
      421 aactttttaa tactcagcac cgctttcctt cagataagac actgttcctt gccttcacat
      481 cgcttgagca agacgcgagc gaagtatggt ccatgcttat tggtcctgcc atcgtcatga
      541 ctgagaccgc cctcggaaaa acgcccattg agccattgac ggcgggtgaa aaactctgtg
      601 catttttgag tggcgcgacg aaatcccagc cagcagctcg caattgacct gtcttctaaa
      661 cgtctgtgcc ataccacaga gatttagtac aaaattaatt aatggagcac taacgctgtc
      721 agcaggtttc tctgagtgaa agattcgtat tatacgcaca gcccagttta cagtttatat
      781 aacagcgcta tatgtttttg tatccgtacc atgccgccta caagcggctg tctgagtacc
      841 tctagccgtg ccagggggta ttagctcaaa tgtgagctga catatctatg gcacagcgcc
      901 aaacctaatc tgactgtccg ccctgcgcca gaagcggacg ctgaacatgg tgtgtacagg
      961 ccaacaatac gatatatttt aaagctacct gattgcagct ttcataaggc tatgggtatt
     1021 caaatgtagc aaagctataa atcaggctta attaaataat gcctttgcga acctacttta
     1081 ggaaagtccg gtagcgacat ttgaagtata tgaccctgtt tttcataaaa agggagagcc
     1141 tggaagctaa aggtatctac aagtccatga acacagcctt tccgcaaacc ttctttttcg
     1201 gccatctcca taagttgact ccccagaccg cggctccttg cagattcact tacccaaaga
     1261 tagtcgatgc aaagccacgg accttttctg tcagcaatta atccgcctac catttcgccg
     1321 ctttcgtttc tgcagtagac cccaagctgc ccatttttac taaaatcgac gaactgagca
     1381 ttgtagcttc ttaatccggc taatagttct tctttatcaa attcagtaac ttgatgtgta
     1441 atttgaatgt ccatacatat ccaattgaac aagtttgcat ttggaatata acgttataaa
     1501 taagttaatt aaatgtatca atagaaagtt tatttttact cctgcggggc aggtcacgtc
     1561 cgctactcgc ttaaagcaaa ctgtcagttg gagtctgagc tggtacaatt aatgtgccac
     1621 tggttagaaa tcagtaatac gattttatca ggctgatact ctggcctgtc aggatttgag
     1681 gtatccaccc ggtttaccag cccactgtat ttggcaccag tggaacccac ttcccgatcc
     1741 aggatatcca gtatccaccg ccgaacctct ttccccaaaa gatatgtgca acctcaagcg
     1801 ccttgtctgg atgatgacca cggtatgaag tttgataacg cgtggaatca gggcgtttgg
     1861 tacgctctcc gttcagcaac tggacgcctt tctccccagc ctttcagcgt tgaagatttg
     1921 ccagcgctgg gtgaagagtg taggcgaatt atgaaaatca cttctgccgt ttatacttcg
     1981 aaaaagacgt tatcagaaag gtggttcgca agcgcggagt tattaaacct ttacttaacg
     2041 aaatacggtt taagttgctt gaattgcagc agaaagaaaa cgacggcttg atgatgctgg
     2101 acaaattaag cgagcatggc atcaatggac tgatacgccg tcaataaaag gaagggtgca
     2161 tggacgatcc cgtcacatca ccaatcacaa cagaagagca caaaacaaca tttcacagcg
     2221 taaatgataa aacacgatgc cattttcaat caaaaacata tgttcaggtc cacaaggaca
     2281 ctacccagaa atctccagac ctatacagaa caagccagta ccgaggaatt gcacactgat
     2341 ctcaacaaca tgcaaagtac tggactatac agtattcagc aaatggtcct gcagttatga
     2401 aatgcgccca cccggtgcag aagaaagaac ctcacgacta aaattatcag catcaggcgg
     2461 tcaccgaacc cgataataaa acggctcatc gccagccacc agctctggag cggtatactc
     2521 cattttttga cgcatccttg atcgccagat aaataacttt tcgtactgag tcatccgtcg
     2581 ggaacacctt gcatttcttt atcgcggcac ggatcacgct gttcagggat tcgactgcgt
     2641 ttgtcgtgta gatggccttg cggatatccg gcggataact gaagagcgta ttgaggtttt
     2701 cccggtgcgc acgccagctt ttgctgattt gcggatattt atcgtcccgg actttcgcga
     2761 acgcatctat cgccatcagt accgcatctt cggtcggggc ctgatagacc atcttccggc
     2821 cgctggtgac ggctttgtag tctttccagg ctacgtattt caggctgtta cgcatcatat
     2881 ggatactgca cagctgaata tgggtttgcg ggaagacgct atttatcgca tccgggaagc
     2941 ccttcagacc atccacacag gcaatcagga tgtcctgaag gccccgggtt ttcagctccg
     3001 tcagcacgct tagccagaac ttttcgcatt cattttcggc cagccacata cccagtaact
     3061 ctttctggcg ttcggtgttg atacccagtg ccaggaagac ggctttgttg attacgctgc
     3121 cattctgacg gactttgacg acaacgcaat ccatataaac aatggggtac agcgcatcca
     3181 gttgccggtt ttgcctctca gtgacctgct cttttacggc gtcggtgact ttagatatca
     3241 gcgaaggtga cacatcggcg tcgtacatct ctttggaggt ggcgacgatt tcgcgggtag
     3301 tcatgccttt ggcgtagagg gataaaattt ggctgtccat ctgcgtaatg cgcgtctggt
     3361 gcttcttaag tagctgcggt tcgaaggtgt tttcacggtc acgcggcgtg ttcagttcga
     3421 tctcgccgtc atcgcataac accgtttttg acgagtagcc attgcgggtg tttgagcctg
     3481 ttttgggggc gtttttctca tacccggggt ggtcagtcag ctacgcattg agcgccgttt
     3541 cgacggttaa tttcgtcagc atacgggaaa acggattgag gtcggcttcg gttttaaggc
     3601 ctttagccag ttcagccgca aggaatttgc gtttcttttc gtccataatt gcctgtctcc
     3661 gttactggag tgaacatatc aaaaacaggc aattacacaa ttttaattac agtctcagtt
     3721 cagtcacatt attgatgagc gactgtacgt taagccaatc aagaccgaga tgaaaatcgc
     3781 tctgccactt tcgctcaccc ctccttccat gggtttacgc ctcagtacgg tgattgatcg
     3841 ttgccgcctg gtaagccgta gcgaatacct tatcagcgct ggcatacgca aaaaccgccc
     3901 gaacgggagt attcatcctg acagcctgac taaaaaattt gttgcggcac gaaaatttac
     3961 cggaataaat ttagtgataa cccaccgaca tttcacgaga tccgcagctt atccggacga
     4021 ctatataaag atgcttacgg ggaagggttt gctcagaaac tcctgggaca tacttccgag
     4081 aacaccacga aactctatat cgacaaacgc gataataaag cttacgtgat gctctgattt
     4141 tgctgtaaaa gaaatgttaa actggatttg gatctgatat aacgaaaaag cccggaatac
     4201 agaaattctg gaaaatttcg gaaatttcgg attattgatc ataagcaact gatttataag
     4261 aaaaacaaaa agagaccgaa tacgattcct gtttacggca a
//
LOCUS       DAJVKX010000219         4283 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.219, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000219 DAJVKX010000000
VERSION     DAJVKX010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4283
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.219"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..367)
                     /locus_tag="OPY25_004366"
     CDS             complement(<1..367)
                     /locus_tag="OPY25_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929807.1"
                     /translation="MRMSKHNLIIYSLLLAAVPISVLADSSTTSAATVGMFSPPTAPS
                     VGHRPGTPRDTYELKFNGLDFSIEKYTPFPGMTIARDDRYLGISDPDNNYQSAETFTT
                     VCTYYQINKDNSQHILKREK"
     gene            complement(388..2370)
                     /locus_tag="OPY25_004367"
     CDS             complement(388..2370)
                     /locus_tag="OPY25_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-partner secretion translocator ZirT"
                     /protein_id="HCS0929808.1"
                     /translation="MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSI
                     SPHLQEGTLEDYAKGKIKALPGQAANHLVNEGMKSAFPEIIFRGGVNLEDGAKYRSSE
                     FDMFIPVQETTSSLLFGQLGFRDHDSSSFDGRTYVNVGVGYRQEVNGWLLGVNTFLDA
                     DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKTSVVHELHDERPAYGFDLRTKGTL
                     PDFPWFSGELTYEQYYGDKVDLLGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGN
                     GGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRNYDIVMAYREQASKI
                     RIMAMPVSGLSGTLVILMATVDSRYPIEKVEWSGDAELLAGLQLQGSLGSGLILPQLP
                     LTATDGQEYSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFV
                     ISTPLPAGEEGKVIEWHYVRERSEEEWASLKPRHIKYQSDTPGLAFKALGGTERDGHW
                     VERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVEVLFTQG
                     TEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWL
                     LPYSLNGESLQNKYIRVRIISDKGNAKGNTATSDAN"
     gene            complement(2445..3290)
                     /locus_tag="OPY25_004368"
     CDS             complement(2445..3290)
                     /locus_tag="OPY25_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929809.1"
                     /translation="MYFKKSLLALAICASVVSVEAVANIRANDMASSATPASVGHRPV
                     ATTNAKKIEVSGELTTGSTLQIADVFIEDEDGDPLSLDKMNNADDIKWYLVDNEAADP
                     SGTPAATGTAFTIPAYAGGKKIKIVYRIKTATGTPDSAFLPATVLLTSASSGVSGDSA
                     ADGTISNKLRSVTINVVNESGKPTDELNGTNDANTPVVGGTLEVVLECAATAAAECEV
                     SNYNFTWQMADAGTPDRFTDLNNTNAEKHKYIIKGTEQNKLFRVHVTPKTTKATPENK
                     RAIRR"
     gene            3587..>4283
                     /locus_tag="OPY25_004369"
     CDS             3587..>4283
                     /locus_tag="OPY25_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0929810.1"
                     /translation="MMMKRAIIVSVLEQIEKNLEERIDIEKLVVITGYSRRSLQDFFK
                     EKCGVSIGKYIRQRKLSRSATLLKLTSQSVTDIAFRMGFDSVQSYSREFKKTFGVNPN
                     NYRKADFWDLRNLRPPYWLDCDGHYQFEICQLTSKEIFGFQTSHQIATNDLPKKASPI
                     KWKIIHETLRTWGENVYCLSSFKPDNTKDQVIAVSSFFGMEHNSVDGGKIPMSRVIKC
                     GKYAKFHFVGHKEQ"
BASE COUNT         1153 a         1061 c          936 g         1133 t
ORIGIN      
        1 gcttttcacg tttaagtata tgctgagaat tatctttatt gatctgataa tacgtacata
       61 ctgtagtaaa cgtttccgca gactgatagt tattatccgg atcgctgatg cctagatatc
      121 tatcatccct cgcaatagtc attcccggaa aaggtgtata cttttcaata gaaaagtcaa
      181 gtccattaaa cttcaattcg taggtatcac gaggtgttcc tggtctgtgc ccaacgctcg
      241 gcgccgtagg aggagaaaac atcccgacgg ttgccgcgga agttgtcgac gaatccgcca
      301 agacgcttat cggcacagcc gccagaagca ggctatagat aataagatta tgtttcgaca
      361 tacgcactgt tgatcctttt taaaacatta attcgcatca gaggttgcgg tattaccctt
      421 agcatttccc ttatcagaaa taattctgac gcggatatat ttattctgaa gcgattcccc
      481 attaagacta taaggaagaa gccaggtggc ctttgtcgcc cccggtacgg attgccagga
      541 tttcatttca tccgagattt cccactgata attaaacgca tcagtacagt ccgtgttatt
      601 tacacaaagc gttctggctc gcatttctgt tccgacgact ggcgcagtaa cgcttccgtt
      661 ggcttcttca gtaccctgcg taaaaagcac ctccacagaa gtgaccttct gcgcaatact
      721 gtctgactgc gcttgtagta gtacggtacc cttcaccgga tgtttatcgt ctggtccgct
      781 tgcttcaata tgtaatttga gcgagcgggc atcatcgccg atatgggtca ccagaacccg
      841 ttcaacccaa tggccgtcac gctctgtacc accgagcgct ttaaatgcca gacccggcgt
      901 atctgattga tacttaatat gacgtggttt gagcgacgcc cactcctctt cagaacgctc
      961 gcgcacgtag tgccactcaa taaccttccc ctcttctccg gcaggaagcg gcgtactgat
     1021 aacaaagttg ccgtcctcaa cctgaacatc gtcattgata acatttatcc aggaacggaa
     1081 actggtctca tcctgtgtca cccttaccgg gatacgctcg gaggtcacgc gagtaccccg
     1141 gctgtcagtc accgttaaat aaaggctata ctcctgaccg tcggtcgccg tcagcggaag
     1201 ttgaggaagg ataaggccgc tgcccaaact cccctgaagc tgaagtccgg cgagaagttc
     1261 cgcatcaccc gaccactcaa ctttctcaat cgggtaacgg ctatctaccg tcgccattaa
     1321 tatcaccagc gtcccggaca ggcctgacac cggcattgcc ataatgcgga ttttactggc
     1381 ctgctcccga tacgccatga cgatatcgta attacgatcg acaaaggcac gccgattagt
     1441 cgtattcgac ggcgccccaa cgttgcggta atcaagctgt tcatgtaacg gcgtaccgaa
     1501 ggaatagttg actctcagac cgccctctgc ctgcgatccg ccgttaccgg cgtcccgata
     1561 tcctgctctg acctcaagca aggggacagg attccagacc agagccgcac ctgcggcgcg
     1621 gggattccgg cttaatgtac cgttacccaa tagatcaact ttatccccgt aatactgttc
     1681 atatgtcagc tcgccactga accagggaaa atcgggaagc gtgccttttg ttcgcagatc
     1741 aaagccatat gccggacgct catcatgtaa ttcatgaact actgacgttt tccagccggt
     1801 gagagggaaa taatagttgc cggaaaaggc cagactgtct ttatagactt ccccgccaat
     1861 gccgccacgc aagtgggaat aacggatgtc ggcatccaga aacgtattga cgccgagcag
     1921 ccatccattg acctcctggc gataacccac accaacgtta acataggtgc ggccatcgaa
     1981 actgctgctg tcgtggtcgc gaaagccaag ctggccaaag agtaaagacg atgttgtttc
     2041 ctggacggga ataaacatat cgaactctga tgagcgatat ttcgcgccat cttcaagatt
     2101 gacgccacca cggaaaataa tctccggaaa agcgctcttc atcccctcgt tcaccagatg
     2161 attagcggct tgccctggta atgcctttat ttttcctttg gcataatcct ccagcgtccc
     2221 ctcctgcaga tgcggagaaa tagacgatgc cgtccctgca atccatgact gaatttcatt
     2281 atcgctatca gcgatgaccg gcagtggaat ctgactggta acaatggccc aggttatata
     2341 tttagtaatg ggttttttag aaaaaaccac tttattgtct cctgctatat ccccctgcct
     2401 ggcagaggga gtatttaaat aagatgttta tttggcgata accatcagcg acggatagcg
     2461 cgtttattct ccggcgtggc tttcgtcgtt ttaggcgtaa cgtggacacg gaacagttta
     2521 ttctgctcag ttcccttaat aatatattta tgcttttcag cgttggtatt attcagatcg
     2581 gtgaacctat ctggtgtccc ggcatccgcc atctgccagg taaagttata attactgacc
     2641 tcacactcag ccgccgctgt ggcggcacat tccagtacca cttcaagggt gccgcctacc
     2701 actggagtgt tggcgtcatt ggtaccgttg agttcatcag tcggtttacc actttcattc
     2761 accacattga tagtgacaga acgtagctta ttagaaattg taccgtctgc ggcggagtcg
     2821 ccgctcaccc cagaagatgc agaagttaat aagacagtgg caggcaagaa tgcactatcc
     2881 ggcgtccccg ttgccgtctt aatccggtaa acgattttaa tttttttacc gcctgcataa
     2941 gcaggaatgg taaaagccgt cccggttgcc gccggggttc cagaaggatc ggcggcctca
     3001 ttatccacca gataccattt aatatcgtcg gcattattca ttttatccag cgataaggga
     3061 tccccatcct catcctcaat aaaaacatcc gctatctgga gggttgaacc ggtcgtcagt
     3121 tccccagaca cttctatctt ttttgcatta gtagttgcca caggacggtg accaacagaa
     3181 gcaggcgtag cagaagaagc catatcattg gctctgatat tcgccaccgc ctctactgag
     3241 accacggatg cacaaatcgc taaagctaat aaagattttt tgaagtacaa aacaattcat
     3301 cccttttatt aaatcattag aaataattat gagatttata atctcacggg ctaaaaattc
     3361 aggattattc aatcatttta accgtctgtg aaattatgcc cttcgccatg ccaattactt
     3421 agctttactg gcaaaagccg atctccaagt gtaaagttta ttcagaaacg tcaagcaatt
     3481 taaatctttc ttgttttgcc agaaaagcta acaacccccc actggtttaa taacaccgta
     3541 tgtcaaacac cttaaatgtt tatattttcg gcttcaataa agaggaatga tgatgaaaag
     3601 agccataata gtctcagtat tagagcaaat agaaaaaaat cttgaagaga ggattgatat
     3661 tgaaaagttg gttgttataa caggttattc gcgaaggagt ttgcaggatt tttttaaaga
     3721 aaagtgtggc gtctctatcg gaaaatatat cagacaacgc aagttgagca gaagcgccac
     3781 tctgctaaag ctgacctctc agtcggtcac agatatcgcg ttcagaatgg ggtttgattc
     3841 agtgcagtcc tatagtcgag agttcaaaaa aacatttggc gtcaatccca ataactatcg
     3901 caaggctgat ttctgggatc tcagaaacct acggcctccc tactggcttg actgtgatgg
     3961 gcattatcag ttcgaaattt gtcagcttac gtcaaaagaa attttcggat ttcaaacatc
     4021 tcatcagatc gcaacaaatg accttcctaa aaaagcgtcg cctataaaat ggaaaatcat
     4081 tcatgagacg ctcaggacgt ggggcgaaaa tgtgtattgt ctctcgtctt ttaagccgga
     4141 taataccaaa gaccaggtca tcgccgtaag cagttttttt ggtatggaac ataattccgt
     4201 cgatggagga aaaataccca tgtcgagggt aataaaatgt ggtaaatatg caaaattcca
     4261 tttcgttggt cataaggaac aat
//
LOCUS       DAJVKX010000220         4268 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.220, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000220 DAJVKX010000000
VERSION     DAJVKX010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4268
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.220"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..356
                     /locus_tag="OPY25_004370"
     CDS             <1..356
                     /locus_tag="OPY25_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCS0929811.1"
                     /translation="LYQVYSQPGAAYWVVEQNGCVVGGGGVAPLSCSEPDICELQKMY
                     FLPVIRGQGLAKKLALMALDHAREQGFKRCYLETTAFLREAIALYERLGFEHISEPLG
                     CTGHVDCEVRMLKDL"
     gene            463..951
                     /locus_tag="OPY25_004371"
     CDS             463..951
                     /locus_tag="OPY25_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3617 domain-containing protein"
                     /protein_id="HCS0929812.1"
                     /translation="MKRLLSAIVFPAMFISISNVYALDIQPGEWKMENIEMRTINPDT
                     KEVLMDEKNSGIATLMCYTPKMSEDSKKMVKGFSTSAGGCTTTFVESTDTKLINETVC
                     NNPDVKSHSIVETTKISDTEFAMTMKSDVDAGGNKTTSINKIKQTFVGKTCSEASKGV
                     KQ"
     gene            complement(1196..1960)
                     /gene="miaE"
                     /locus_tag="OPY25_004372"
     CDS             complement(1196..1960)
                     /gene="miaE"
                     /locus_tag="OPY25_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase
                     MiaE"
                     /protein_id="HCS0929813.1"
                     /translation="MNYPQILSPVLNFLHCPTPQAWIVQARDPQNLPLLLTDHLICEL
                     KAAQTALLLVRKYVADKSGADALLAWLQPYEAFAFRQGPEPDFVALHKQISKSAMPQT
                     DDPWGRQLIDRMVLLIKEELHHFWQVREVMQARNIPYVKITASRYAKGMLKAVRTHEP
                     LTLIDKLICGAYIEARSCERFAALAPWLDEDLQTFYLSLLRSEARHYQDYLALAQQIS
                     AEDISARVRYFGDVEADLILSPDREFRFHSGVPAAG"
     gene            complement(2019..2435)
                     /gene="rraB"
                     /locus_tag="OPY25_004373"
     CDS             complement(2019..2435)
                     /gene="rraB"
                     /locus_tag="OPY25_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HCS0929814.1"
                     /translation="MANPELLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDFE
                     TLEKAAVEAFKLGYEVTEPEELEVEEGDTVICCDILSECALNAELIDAQVEQLMNLAE
                     KYDVEYDGWGTYFEDPNGEEGDDDDYVDEDDDGVRH"
     gene            2601..3605
                     /gene="argF"
                     /locus_tag="OPY25_004374"
     CDS             2601..3605
                     /gene="argF"
                     /locus_tag="OPY25_004374"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCS0929815.1"
                     /translation="MSTFYQKPFLKLLDFTASELTALLQLAAKLKADKKNGKEEQKLV
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGSSGSQIGHKESIKDTARVLGRMFD
                     GIQYRGYGQEIVETLAEYSGVPVWNGLTDEYHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPKACWPQAALVAECSAMAKKNGGAITLTED
                     IASGVKGADFIYTDVWVSMGEPKEKWAERIALLRDYQVNSQMMALTGNPQVKFLHCLP
                     AFHDDETTLGKKMAEEYGLHGGMEVTDEVFESAASIAFDEAENRMHTIKAVMVATLSK
                     "
     gene            complement(3679..4131)
                     /locus_tag="OPY25_004375"
     CDS             complement(3679..4131)
                     /locus_tag="OPY25_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCS0929816.1"
                     /translation="MIVGNIEHLEAWLPTALRQAIEHVNAHVTATTAPGKYDIDGDRL
                     FYMISENMTEPGESRSAEYHARYLDIQIVLQGQEGMAFSTRPAGTPHTDWLADKDIAF
                     LPTSVDEKTVVLNEGDFVVFYPGEVHKPLCAVGEPARVRKAVVKMLMA"
BASE COUNT         1117 a         1058 c         1053 g         1040 t
ORIGIN      
        1 aactgtatca ggtttatagc caaccgggcg cggcctactg ggtggtagag caaaacggtt
       61 gtgtggtggg cggcggcggc gtggcgccgt tatcctgtag cgaaccagac atttgtgaac
      121 tgcaaaaaat gtatttttta ccggtaattc gtggtcaggg gctggcgaaa aagctggcgc
      181 tgatggcgct ggatcatgcc cgtgaacagg gttttaaacg ctgctatctg gaaacaacgg
      241 cttttttacg cgaggcgatt gcgctatacg aacgtttagg atttgaacat attagcgaac
      301 cgctcggctg caccggacat gtcgattgcg aagtgaggat gttaaaggat ctctgaaaac
      361 caggcgttta tttatcctcg ccaggtatta tttttgctga tataagtaat cccggaaaca
      421 tcctgttatc cgggaatcac ttattattca aggaagttat aaatgaaacg cctattatca
      481 gcaattgttt tccccgctat gtttattagt atctctaatg tatatgcatt agatatacag
      541 cccggcgaat ggaaaatgga aaatatagaa atgcgcacca tcaatccaga tacaaaagaa
      601 gtattaatgg atgaaaaaaa ttcgggcata gcgacgctta tgtgttatac ccctaaaatg
      661 tctgaagatt ctaaaaaaat ggtgaagggt ttttctacca gtgcaggcgg ttgcacgaca
      721 acatttgtag aaagtacgga taccaaactg atcaatgaga ctgtgtgtaa taatcctgat
      781 gtcaaatcgc actctattgt agaaacgacg aaaataagcg atacagaatt tgcgatgacc
      841 atgaaatcgg atgtcgatgc aggaggtaat aaaacaacct ccatcaacaa aattaaacaa
      901 acctttgttg gcaagacctg ctctgaagcg tcaaaaggcg tgaaacagta actatttcaa
      961 cacaaaaacc cgtagtgatt gatgcaataa tggcattgtt cacggtcacc tttcgggaat
     1021 ataacactga gtgagttctt tttgcctgcc gcagggcagg ctttactcag gacagaatat
     1081 catgaaaatg acttttcctg ctcgccagca gcttgatgcc gggcggatga ccaccacaaa
     1141 ttttgcagac ggcgacagcg taaaagataa aaacgctaat ctttaatttt acgctttatc
     1201 cggcggctgg cacgccgcta tgaaaacgaa actcgcggtc tggcgacaag ataaggtcag
     1261 cttccacgtc gccaaaatag cgcacgcgcg cagaaatgtc ctcggcggaa atctgctgcg
     1321 ccagcgccag gtaatcctga taatgccgcg cttcggagcg cagaagcgag agataaaacg
     1381 tctgtaaatc ctcatccagc cagggggcca gagcggcaaa acgttcgcag gagcgggctt
     1441 cgatatacgc cccgcaaatc agcttatcaa ttaaggtgag cggttcgtgc gtgcgtaccg
     1501 ctttcaacat tccttttgcg tagcggctgg cggtgatttt cacataagga atgtttctgg
     1561 cctgcatgac ctcgcgtacc tgccaaaaat ggtgcaactc ctctttaatc aataacacca
     1621 tacggtcgat aagctgacga ccccaggggt catcagtttg cggcatggcg cttttgctaa
     1681 tctgtttatg cagggcaaca aaatccggct ccggcccctg acgaaacgcg aacgcctcgt
     1741 aaggttgcag ccaggcgagc agcgcgtcgg cgcccgattt atcggcgaca tatttacgca
     1801 ccaacagcaa cgcggtttgc gcagccttca gttcgcagat caagtgatcg gtaagcagaa
     1861 gaggaagatt ttgcggatcg cgggcctgga caatccacgc ctgcggcgtc gggcaatgca
     1921 ggaaattaag caccggagag agtatttgcg ggtaattcat acgtaacctg taaaaaaata
     1981 cgacagcaga cgctgccgta ccgtcatact atgcagcttt agtgacgcac gccgtcgtca
     2041 tcttcatcga cataatcgtc gtcgtcaccc tcttcgccat tagggtcttc gaaataggtt
     2101 ccccagccgt cgtattcgac atcatatttt tccgccaggt tcatcagttg ctcaacctga
     2161 gcgtcgatga gttcggcgtt caacgcgcac tcgctgagga tgtcgcaaca aataaccgta
     2221 tcgccctctt ccacttccag ctcttccggc tccgtcactt catagccgag tttaaaggct
     2281 tctaccgcgg ctttttccaa cgtttcgaaa tcgtcagcgg aaaggtgatg ctcgatagtg
     2341 tacagcgcat ccggatcgct gccgtcctca agtaactctt caataattaa ccgcgtttct
     2401 tcacgctgct cttccagtaa ttccgggttt gccatagctc gttcctcata gatgtcctgc
     2461 cgatactctt attgtcacat accgccgacg ttgcctccac cttatcgaga aaagttttat
     2521 caaacagggt tgcaaatgaa taatcatcca tataaagtga attttaattc aatgagaggc
     2581 ctaagccatg tgagggaagt atgtctacgt tttaccaaaa acctttttta aagttacttg
     2641 atttcaccgc cagtgaactc actgctctgt tgcagcttgc tgccaaactg aaagccgata
     2701 agaaaaacgg taaagaagaa caaaagctgg tgggtaaaaa tattgcgctc atcttcgaaa
     2761 aagactcgac ccggacacga tgctctttcg aagttgccgc atacgatcag ggggcgcgcg
     2821 tgacgtacct gggttccagc gggagccaga tcggtcataa ggagtccatc aaagatactg
     2881 cccgcgtcct gggccggatg tttgacggta ttcagtatcg aggatatggc caggagatcg
     2941 tcgaaacgct ggctgaatat tccggtgtgc cggtatggaa cggtttaacc gatgagtatc
     3001 acccaacgca attactggcg gatctgctca ccatgcagga acatctgccg ggtaaagcct
     3061 ttaacgagat gacgttggtc tatgccggag acgcacgcaa taacatgggt aactccatgc
     3121 tggaagccgc cgcgttaaca ggattggatc tccgtctggt cgcgccaaaa gcctgctggc
     3181 cgcaagccgc gttagtggcg gagtgcagcg ccatggcgaa aaagaacggc ggcgccatca
     3241 ccctgaccga agatattgcc tcgggcgtaa aaggcgcgga ttttatctat accgatgttt
     3301 gggtctctat gggcgaaccc aaagagaaat gggcggagcg tattgccctg ctgcgtgatt
     3361 atcaggtcaa cagccagatg atggcgttaa ccggcaatcc gcaggttaag ttcctgcatt
     3421 gtctgcctgc gttccatgat gacgaaacca cgctcggcaa aaaaatggcc gaagagtacg
     3481 gtttacatgg cgggatggaa gtgaccgacg aggtttttga gtctgcggcc agcattgcct
     3541 ttgatgaagc ggaaaaccga atgcatacca tcaaagcggt aatggtagcg acgctgtcta
     3601 aataatgtcg ttatgatgcc ggatggcggt tggcctacaa gatcgcaacg tgcaggcgcc
     3661 gccatccggc acaaaatatt acgccatcag cattttcaca accgctttac gtacccgcgc
     3721 cggttctccc accgcgcaca ggggcttatg cacttcgccg ggataaaaca ccacaaagtc
     3781 accttcgttc aggacgacgg ttttctcgtc gacgctcgtc ggtaaaaatg caatgtcttt
     3841 atccgccaac cagtccgtgt gcggcgttcc cgcaggccgg gtactgaatg ccatcccttc
     3901 ctgaccttgt agcacaatct gaatatcaag ataacgggcg tgatactctg cgctgcgcga
     3961 ttcgcccggc tccgtcatat tttcagaaat catataaaac agcctgtcgc cgtcaatgtc
     4021 atacttacct ggcgcggtcg ttgccgtgac atgcgcgttg acgtgctcaa tcgcctgccg
     4081 taacgccgtc ggcagccagg cctccagatg ttcaatattg ccaacaatca tcgcatctcc
     4141 ttagttaaaa cagcgtttta tttttctctt tatacgagaa aaatggctgc catactaccc
     4201 ttactctcat cgattttgcg ccagcgcatg tttatcgcca gcggtgttta tatattgtta
     4261 atagttcg
//
LOCUS       DAJVKX010000221         4247 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.221, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000221 DAJVKX010000000
VERSION     DAJVKX010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4247
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.221"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            141..257
                     /locus_tag="OPY25_004376"
     CDS             141..257
                     /locus_tag="OPY25_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929817.1"
                     /translation="MINYDVLHINVALAHCRNAINRVKLKHNLIFLQSRSEL"
     gene            254..649
                     /gene="uspC"
                     /locus_tag="OPY25_004377"
     CDS             254..649
                     /gene="uspC"
                     /locus_tag="OPY25_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001766287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HCS0929818.1"
                     /translation="MSYTHILVAVAVTPESHQLLAKAVSIARPVQAKVSLITLASDPE
                     LYNQFAAPMMEDLRAVMHEETENFLKMLGEKADYPIEQTFIASGELSQHILAVCRKHH
                     VDLVICGNHNHSFFSRASCSAKVSSAPAR"
     gene            complement(699..2120)
                     /gene="otsA"
                     /locus_tag="OPY25_004378"
     CDS             complement(699..2120)
                     /gene="otsA"
                     /locus_tag="OPY25_004378"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HCS0929819.1"
                     /translation="MSRLVVVSNRIAPPDNKGGAGGLAVGVLGALKAAGGLWFGWSGE
                     TGNEDEPLKKVTKGNITWASFNLSEQDYEDYYCQFSNAVLWPAFHYRLDLVQFQRPAW
                     EGYMRVNALLADKLLPLIKENDIIWVHDYHLLPFASELRKRGVNNRIGFFLHIPFPTP
                     EIFNALPPHDELLEQLCDFDLLGFQTENDRLAFLDSLSSQTRVTTRSGKQHIAWGKDF
                     QTEVYPIGIEPDEIALQAAGPLPPKLAQLKAELKNVKNIFSVERLDYSKGLPERFLAY
                     EALLENYPQHRGKIRYTQIAPTSRGEVQAYQDIRHQLETEAGRINGKYGQLGWTPLYY
                     LNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEFVAAQDPANPGVLVLSQFAGAAN
                     ELTSALIVNPYDRDDVAAALNRALTMPLAERISRHAEMLDVIVKNDINRWQERFIHDL
                     KEVTPRSPERQQQNNVATFPKLA"
     gene            complement(2095..2898)
                     /gene="otsB"
                     /locus_tag="OPY25_004379"
     CDS             complement(2095..2898)
                     /gene="otsB"
                     /locus_tag="OPY25_004379"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HCS0929820.1"
                     /translation="MAEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQL
                     LDRLAAHNAGALALISGRSMTELDALAKPFRFPLAGVHGAERRDISGKTHIVRLPEAV
                     VREVEALLRSTLAALPGTELETKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQ
                     PGKCVVEIKPKGTNKGEAIAAFMQEAPFTGRIPVFVGDDLTDEAGFGVVNHAGGISVK
                     VGVGATQAAWRLESVPDVWRWLEQINYPQQEQQVMNNRRDGYESFSRSI"
     gene            complement(3121..3297)
                     /gene="araH"
                     /locus_tag="OPY25_004380"
                     /pseudo
     CDS             complement(3121..3297)
                     /gene="araH"
                     /locus_tag="OPY25_004380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707790.1"
                     /note="Part of the ABC transporter complex AraFGH involved
                     in the high affinity transport of arabinose; incomplete;
                     partial in the middle of a contig; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose ABC transporter permease AraH"
     gene            complement(3532..4089)
                     /locus_tag="OPY25_004381"
     CDS             complement(3532..4089)
                     /locus_tag="OPY25_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HCS0929821.1"
                     /translation="MKKVAVLLAPGFEEAEAIVTLDILRRLHIDVETLACAESRAVVS
                     YHDIPMVADSTLSERQQALFDAVVLPGGPQGSANLAANPAVIAFVARHDAAGKLICPI
                     CSAAARVLGAHGLLKGRRYVCSGDLWKAVPEGVYVDAPVVEDGNLISGKGLGHVFDFA
                     LTLSARLLGDDALVREQAEHIYYPW"
BASE COUNT         1076 a         1170 c          976 g         1025 t
ORIGIN      
        1 tcacagcata cgccctcctc tgttaaaaat aagctcattt gatttaactt ttagctttcc
       61 ttgttcaccc gtttaaataa agcatcctgg tggtgtgtaa aaagtgtctt atgccacgat
      121 tctttacata agaataatca atgattaatt atgatgtcct tcacattaat gtggcattag
      181 cgcattgcag aaatgcgata aacagagtaa agctaaagca caatctcata ttcttgcaat
      241 caaggagcga gttatgagct acacccatat tcttgtcgcc gttgccgtca ccccggaaag
      301 tcaccagcta ctggctaaag cggtctctat cgcccgccct gttcaggcga aagtaagcct
      361 gattactctc gcttccgatc ctgaactgta taaccagttc gccgcgccca tgatggagga
      421 tttacgcgcg gttatgcatg aagagaccga gaattttctt aaaatgctgg gggaaaaggc
      481 ggattatccg attgaacaaa ctttcatcgc atcaggtgag ttaagccagc atattttggc
      541 tgtgtgccgc aaacaccatg ttgatctggt catttgcggc aaccataacc acagtttctt
      601 ttcgcgcgcg tcctgctcgg caaaagtgtc gtcagcgcca gccaggtaga tgtgttgctg
      661 gtgccgttag cgggcgacta gtcgccgctc gcgatatctc aggccagctt agggaacgtc
      721 gccacgttgt tctgctgctg acgctcaggg ctacgcggcg tgacctcctt taggtcatga
      781 ataaaacgct cctgccagcg gttaatgtca tttttaacga tcacgtccag catttccgca
      841 tgacgcgaaa tacgctcggc aaggggcatc gttaacgcac gattgagcgc cgccgccacg
      901 tcatcccgat cgtaaggatt gacgattaac gccgacgtca gttcattcgc cgcgccggca
      961 aactgtgaca gtaccagtac gccaggatta gcggggtcct gcgcggcgac aaactctttc
     1021 gccaccaggt tcatcccgtc acgcaacggg gtgacgagcc cgacgtctga ataacggaat
     1081 atcttcatta acagtttacg gtcgaaatgc tgattcagat aatagagcgg cgtccagccc
     1141 aattgtccat atttcccatt aatccggcct gcttctgtct caagctggtg gcgaatatcc
     1201 tgatatgcct gtacttcgcc gcgtgacgta ggcgcaattt gggtataacg aatttttccc
     1261 cgatgctgcg gatagttttc cagtagcgct tcatacgcca gaaaacgttc cggcagccct
     1321 ttcgaataat ccagccgctc aacggaaaaa atattcttca catttttcag ttccgccttg
     1381 agctgcgcca gttttggcgg caacggcccg gcagcctgca gagcaatctc atcgggctca
     1441 ataccgatag gatacacttc tgtctggaag tctttacccc acgcgatatg ctgcttgccg
     1501 ctgcgagtcg tgactcgcgt ttgactcgaa aggctatcca gaaaagccag gcgatcattt
     1561 tcggtctgga acccgagcag atcaaagtca cacaactgct ccagcagttc atcatgtggc
     1621 ggtaaagcgt taaaaatctc cggggtcggg aatggaatat gcaggaaaaa accaattcgg
     1681 ttgttcacgc cgcgtttacg cagctcgctg gcaaacggta acaggtggta gtcatgcacc
     1741 caaatgatgt cgttctcttt aatgaggggc aataacttat ccgctaataa cgcattcacc
     1801 cgcatatagc cttcccatgc aggacgctga aactgtacca ggtccagacg atagtggaac
     1861 gctggccaga gaaccgcatt ggaaaattga cagtaataat cttcgtaatc ttgttcactc
     1921 aggttaaacg atgcccaggt aatattacct tttgtcacct tttttaatgg ctcatcctcg
     1981 ttacctgtct cgccactcca gccgaaccac aacccgccag ccgcttttag cgcgccaagc
     2041 acgccaacag cgaggccgcc ggcgccgcct ttattatccg ggggggcaat tcgattagat
     2101 actacgacta aacgactcat agccatctct cctgttattc attacttgtt gttcttgttg
     2161 tggataattg atttgttcca gccagcgcca gacatcgggt acgctttcca gccgccatgc
     2221 cgcctgggtt gccccgacgc ccacttttac ggaaattccg ccagcgtgat tcaccacgcc
     2281 aaagccagcc tcatcggtca aatcgtcgcc cacaaaaacg ggaatccgtc ccgtaaaggg
     2341 cgcctcctgc ataaaggcgg caatcgcttc gcctttatta gttcccttag gtttgatttc
     2401 cacaacacat ttaccaggct gcaacgccag ttgcggccag tgctgcgtaa cgtgttgcgc
     2461 aagcgccaac agcgccgctt catgttccgg agcctgacgg tagtgcagcg caaacgccat
     2521 cccctttgtc tccagctccg ttccgggcag cgctgcaagc gtcgaacgta ataacgcctc
     2581 cacctcacgg actaccgctt caggaaggcg cacgatatgg gttttaccac tgatgtcacg
     2641 acgctctgcc ccgtgaacgc cagcgagcgg aaagcgaaaa ggcttcgcca aagcatccag
     2701 ctcagtcatt gaacgccctg aaatcaatgc cagtgcccct gcgttgtgcg ccgcgagacg
     2761 gtctaacaac tgaaggattt tatgcggtac cactacctga tcgggatgag gctttatctc
     2821 tgccaatgtg ccatcaaggt caaaaaaata cgcatagttc gcagtgagtt cgggggatac
     2881 ggttaacggt tctgccaccc tggtctcctc cttatcatca tattgagact cacaaacggt
     2941 ctcattagtc atgtaagtat agacagtgtg acgctgctcg ccatttagaa agaccatcgc
     3001 cagccggggt agcggttggc gatgacgtga agctatactg tttagttgag tgttaattca
     3061 tcaaatcata cgcttcgctt tttgcttata atggtcgaag ataactgctg ccagaaggat
     3121 tcagccgcga accacgtact gtgcaaaagg tgaaatgttg agcaggttca tcgcgttctc
     3181 caccgttcct gatatcagta cgctcgccac cacatatgag atttttccga ggccgcctct
     3241 caggaaaacg ccccctaata cgcacgcaga aataacgatt aactcataac ccagggaatt
     3301 cattgacctg ctttagcgtt ttttatgtag ggtaaaatca aacgattctt gttagagaag
     3361 acgtaaaacg gtgcactgtc tttcattcat tagataaatg ctgatggctg gaatagtttt
     3421 agcggaaaat gacataaccc agagcgaatt catcagccaa aaggcaggaa agccagcaca
     3481 ttaatccata acatcagcca gctaatcctt acggccctgg gtgaataacg attaccaggg
     3541 ataatagata tgttcagctt gttcgcgaac cagcgcatcg tctcccagca gtctggcgga
     3601 aagggttagc gcgaaatcaa agacatgacc caaccctttg ccgctaatta aattaccatc
     3661 ttcaaccacg ggcgcatcca catagacacc ttccggaacc gctttccaca ggtcgccgga
     3721 acagacataa cgacgcccct tcagcaatcc gtgagcaccc agcacccttg ccgccgcgga
     3781 acagatagga caaattaatt tgcctgccgc atcatgacgc gcaacgaaag cgatcaccgc
     3841 cggattagcc gccagattag cgctcccctg cggaccgccc ggcagcacta ccgcatcaaa
     3901 aagcgcctgc tggcgttcac tcagcgtgct gtccgcaacc ataggaatat catggtaact
     3961 caccaccgcc cgtgattcag cacacgccag cgtttcgacg tcgatatgca aacgtcgcag
     4021 aatatcaaga gtaacaatgg cctctgcttc ttcaaatcct ggcgccagta gcaccgcgac
     4081 ctttttcatt gactgctcct tgttaacgag tcacccagca aaactgcgct caaccgaata
     4141 acgtgctcgt atgattaatg atattaaaaa tgatctaccg caaaatcggc tagtttataa
     4201 aaacaggcat atttgctctc aaccgtttat gcgtgtgata tccagac
//
LOCUS       DAJVKX010000222         4092 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.222, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000222 DAJVKX010000000
VERSION     DAJVKX010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4092
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.222"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..3853)
                     /gene="bapA"
                     /locus_tag="OPY25_004382"
     CDS             complement(<1..3853)
                     /gene="bapA"
                     /locus_tag="OPY25_004382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-associated protein BapA"
                     /protein_id="HCS0929822.1"
                     /translation="MRLLAVVSKLTGVSTTVESSAVTLNAPSIVKLSVARDEISQLTR
                     INQDLVVRLHSGETITIKNFYVTNDLGASQLVLAENDGTLWWVENPQAGLHFEQIADI
                     NELLVTSGASHEAGGAVWPWVLAGAVAAGGIAAIASSGGGDSHHHSDGDNPPPDNTNP
                     DGNPPDNSNPGGSNPNGNTPGSSNPVDTTPPLAPGELLISADGKTVSGEAEAGSLITI
                     KDPSGNVVGEGKADSDGKFSIDLTAPQISGEQLTVTATDDAGNTGPSATIDAPNIPLP
                     DTPVITAAIDDAAPLTGTLSNNQFTNDNTPTLEGTGSAGTVIHIYANGQEIGSTTVDT
                     SGNWHFAITSALADGENHFTAIATNVKGESSESARFTLTIDTLSPDAPRVELMADNTG
                     LLTGPLQNNDRTDEAKPLFSGQGEAGNTITIKEGSTVIGSATVDENGRWTFTPTTPLS
                     DGEHTFTVEQSDKAGNASRVTTTPTIIVDTTPPDAAIIDNVAKDGTTVSGTAEAGSTV
                     SIYDPAGNYLGSTITGENNHFSITLNPAQTHGERLEARIQDAVGNIGPATEFTASDSQ
                     YPAQPTILTVTDDAGAVTGLLKNGDATDDNRPTLSGTAEPGSTISINDNGFPVPSFPP
                     IVADADGKWSFTPSLALADGDHVFTATATNDRGTSGQSVAFTIDIDTQPPVLEGLAVS
                     DVGDRLTGTTEAGSTVVIKDSLGNTLGSGTAGDDGTFSIGISPAKINGETLSISVTDK
                     AANSGPVETLNAPDKTAPAAPNGLIVATDGLSVSGQAEAGATVTIRDSSNTVLGSAVA
                     NGNGQFIVPLNAAQTNGQALIATATDIANNESAAATVDAPDSTAPEMPKNVVISEDGA
                     SISGTAEPGSSITITTPDGTPLGSGKADGEGHFTLPLAPAQTNGEQVTVTATDSANNV
                     SPPTTAQAPDITAPDKPIITQVLDDVESFTGPLVNGQTTNDNRPTLSGTAEAGARVEI
                     FDNGVSLGLATLQPNGGWTFTPSQNLGEGAHRLTVIATDAKGNASPAGNESPESISFT
                     LRIDTQAPDAPQIVSAAITGGEGEVLLANGSITNQRMPTLSGTGEPGAIITLYNNGVE
                     LATVQVNPQGSWTYPLTRNLSEGLNILTATATDAAGNSSPTSGVFSVTLDTQPPAQPD
                     APLISDNVAPVIGNIGNNGATNDTTPTFSGTGEIGSTIILYNNGSEIGRTTVGDNGSW
                     NFTPAALTPETYTITVTETDIAGNISPPSASVTFTLDTTAPANPVITFAEDNVGEVQD
                     TIVSGATTDDNTPVIHGTGDIG"
BASE COUNT          765 a         1060 c         1234 g         1033 t
ORIGIN      
        1 tgccgatgtc gccagtgccg tgaatgaccg gtgtattgtc gtcagtggtt gcgccgctga
       61 caatagtatc ctggacttcg ccgacgttat cttcggcaaa agtgataacc ggattggcgg
      121 gcgcagtggt gtctagcgta aaagtgactg aggcggaagg tggactgata ttgcccgcta
      181 tatcggtttc cgtgacggta atggtatagg tttctggcgt cagtgccgca ggcgtaaagt
      241 tccagctacc gttatcgcct accgttgtgc gaccaatttc actgccatta ttgtagagaa
      301 ttatcgtgct gccgatctct cccgtgccgc tgaaggtcgg cgtggtatcg ttcgttgcgc
      361 cattattgcc gatgttgccg ataaccggcg cgacgttatc gctgattagc ggcgcgtcag
      421 gctgcgctgg aggctgggta tcaagggtaa cggagaaaac gccggaggtc gggctactat
      481 tgcctgcggc atccgtggcg gtggccgtca ggatgtttaa cccttcgctc agattacggg
      541 ttagcggata ggtccagcta ccctgtggat tgacctggac ggtagccagt tctacgccgt
      601 tattgtacag ggtgatgatg gcgccgggtt cgccggtgcc gctgagggtc ggcatacgct
      661 gattggtaat actgccgttt gccagtagca cctcgccttc tccgcctgtg atggcggctg
      721 acacgatctg cggcgcatcc ggcgcctggg tatcgatgcg tagggtaaag ctgatggatt
      781 ccggactttc gttccccgcc ggactggcat tgcctttagc gtcggttgcg attacggtca
      841 gtcgatgcgc gccttcacct aaattttgcg acggcgtaaa cgtccagccg ccgttgggct
      901 gtagcgtggc gagccccagc gaaacgccgt tatcaaaaat ttcgacacgc gcgccagcct
      961 ccgccgtacc gctaagggtg gggcggttgt cattggtggt ttgtccgtta accagcggcc
     1021 cggtgaagct ttcaacatcg tccagcacct gggtgataat gggcttatcc ggggcggtga
     1081 tatcgggcgc ttgcgctgta gttggcgggc tgacgttgtt ggcgctgtcg gtggcggtga
     1141 cggtaacctg ttcgccgttg gtctgtgcgg gggcgagggg aagggtaaaa tgaccttcgc
     1201 catctgcttt gccgctgccg agcggcgtgc cgtccggcgt ggtgatcgta atggagctac
     1261 ccggttcggc ggtgccgctg atactggcgc catcctcact aattaccacg tttttcggca
     1321 tttctggcgc ggtactgtcc ggcgcgtcga ccgtcgcggc ggcgctttcg ttgttcgcta
     1381 tatcggtggc ggtagcgata agcgcctggc cgttagtctg cgccgcattc agcggaacga
     1441 taaattgtcc gttgccgtta gcgacggcgc tgccaagtac ggtattgcta ctgtcgcgga
     1501 tagtgaccgt tgccccggct tccgcctgac cgcttacgga cagaccgtcg gtcgccacga
     1561 taagaccgtt cggtgccgca ggcgcagttt tatccggcgc gttcagcgtt tctaccggac
     1621 cgctattcgc ggctttatcg gtaacgctaa tgcttaatgt ttcaccgtta attttcgccg
     1681 ggctaatacc tattgagaag gtgccgtcgt cgcctgccgt tccactcccg agcgtatttc
     1741 ccaggctatc tttgataacc acagtgctgc cagcttccgt agtgccggtg agtctgtcgc
     1801 cgacgtcgct aactgccagg ccttccagca ccggcggctg cgtgtcgata tcaatggtaa
     1861 aggcgacgga ctgcccgcta gtgccgcgat cgttggtcgc ggtagcggta aagacatggt
     1921 cgccatcggc aagcgccagc gagggggtaa agctccattt gccgtcagcg tcagcgacaa
     1981 tgggcggaaa gctcggaaca ggaaagccat tatcgttaat cgatatcgta ctgcctggtt
     2041 cagcagtacc gctgagggtt gggcggttat catctgtggc atcgccattt ttcaacagcc
     2101 cggtaacggc gccagcgtca tccgtcacgg taaggatagt cggctgggca ggatactgtg
     2161 agtcagaagc ggtaaactct gtggcggggc cgatgttacc gacggcgtcc tgaatacgcg
     2221 cttccagacg ctcgccgtgg gtctgggccg gattcagcgt gatgctgaag tggttatttt
     2281 ctccggtaat cgtggagccc aggtaatttc ccgccgggtc atagatcgac acggtactgc
     2341 cagcttcagc ggtgccgcta acggttgtgc cgtctttcgc gacattatca atgatagcgg
     2401 cgtccggcgg cgtggtgtcc acaatgatag taggcgttgt cgtcacgcgg cttgcgtttc
     2461 cggctttgtc gctctgttcg acggtaaagg tatgttcgcc atcgcttaac ggcgtagtcg
     2521 gcgtaaaggt ccagcgtcca ttttcgtcta cggtagcgct gccgataacg gttgaaccct
     2581 ctttaatcgt gatggtattg cctgcctctc cctgcccgga aaatagcggt tttgcctcgt
     2641 cagtccggtc attattctgt agcggtccgg tgagcaaacc ggtgttatcg gccatcagtt
     2701 caacgcgtgg agcatcgggg ctgagtgtgt cgatagtcag cgtaaagcgg gctgattcgc
     2761 tactttcgcc tttaacgtta gtcgcaatgg cggtgaaatg attttcccca tccgctagcg
     2821 cgctggtaat ggcaaaatgc cagtttccgc tggtatcaac tgttgttgag cctatttcct
     2881 gaccattggc gtaaatatgg atgactgtgc ctgcgctgcc ggtgccctcc agagtggggg
     2941 tattgtcgtt cgtaaactga ttattgctca gcgtgccggt gaggggagcg gcatcatcga
     3001 tagcggcggt gataaccggt gtatcgggga gaggaatgtt gggcgcatca atggttgcgg
     3061 atgggccggt attgccggca tcgtcagtcg cagtcacggt aagttgttcg ccgctaatct
     3121 gtggcgctgt cagatcaata ctaaatttac cgtcgctatc cgctttgccc tcgccaacga
     3181 cgttgcctga gggatctttg atggtaatga gactgcccgc ttcggcctcg ccgctcaccg
     3241 tttttccgtc cgctgaaatc aataattcgc cgggagcgag aggcggggta gtatctacag
     3301 gattactgct acctggagta ttgccgttag ggttactgcc gccgggattg ctgttatcag
     3361 ggggattacc gtcaggattg gtgttatcgg ggggcggatt atcgccatcc gaatgatggt
     3421 gggaatcgcc gccgccggaa gacgcgatag cggcaatgcc gccagccgcc accgcgccag
     3481 ccagtaccca cggccaaacg gcgccgcctg cttcatggga agcgccggaa gtgaccagca
     3541 gctcattaat atcagcgatt tgttcaaaat gtagcccggc ttgcggattt tccacccacc
     3601 ataacgtgcc atcgttttcc gccagtacca gctggcttgc gcccagatcg ttggtaacgt
     3661 aaaagttttt aatcgtgatc gtttcgccgg aatggagcct caccaccaga tcctgattaa
     3721 tgcgcgtaag ttgactaatt tcatcccggg ccactgataa tttaacaatt gaaggcgcgt
     3781 taagagtgac cgctgaggat tccacagtgg tggagacgcc agtcaatttc gaaaccacgg
     3841 cgagtagacg cataaattag ctcctgatgg atttgctctg tgtattaatt aacgggcacg
     3901 acgttcaggg caaaatgcgt agacgagcct tcccgtttat cgtgagagat gaatttccgt
     3961 agccatattc ttttttatga gcgtaggtga aggtctggtt ttctcgtcga ataaccattt
     4021 gttttttgtg cctgactagt gctttcgtat tagatgatat agtcagaaaa aaatctttct
     4081 gcaaattaag at
//
LOCUS       DAJVKX010000223         4028 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.223, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000223 DAJVKX010000000
VERSION     DAJVKX010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4028
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.223"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            34..1695
                     /gene="recN"
                     /locus_tag="OPY25_004383"
     CDS             34..1695
                     /gene="recN"
                     /locus_tag="OPY25_004383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCS0929823.1"
                     /translation="MLAQLTISNFAIVRELEIDFQSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGATRADLCARFALKDTPAALRWLEENQLEEGRECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHTHQQLTKPEQQKSLLDSYANEAALAQQMA
                     AHYQLWHQSCRDLAHHQQQSQERAARAELLQYQLKELNDFNPQAGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALLADGEDVNLQSQLYSAKQLVSELVGMDSKLSGILDMLEEATIQ
                     LTEASDELRHYCERLDLDPNRLFELEQRIAKQISLARKHHVSPEALPQLYQSLLEEQQ
                     QLDDQADSLETLTLAVNKHHQQALETAQALHQQRQFYAQELGQLITESMHLLSMPHGL
                     FTIDVKFDEHHLSNDGADRVEFKVTTNPGQPLQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHFFVSKE
                     TDGAMTETHMQPLDKRARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            1844..2182
                     /gene="bamE"
                     /locus_tag="OPY25_004384"
     CDS             1844..2182
                     /gene="bamE"
                     /locus_tag="OPY25_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HCS0929824.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTPTDVA
                     KVRVGMTQQQVAYALGTPMMTDPFGTNTWFYVFRQQPGHENVTQQTLTLTFNSSGVLT
                     NIDNKPALTK"
     gene            complement(2348..2638)
                     /locus_tag="OPY25_004385"
     CDS             complement(2348..2638)
                     /locus_tag="OPY25_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HCS0929825.1"
                     /translation="MPDKLVVEVAYALPEKQYLQRVTLEEGATVEEAIRASGLLELRT
                     DIDLAKNKVGIYSRPVKLTDTVQDGDRVEIYRPLIADPKALRRQRAEKSAGR"
     gene            complement(2628..3065)
                     /locus_tag="OPY25_004386"
     CDS             complement(2628..3065)
                     /locus_tag="OPY25_004386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001543334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RatA family
                     toxin"
                     /protein_id="HCS0929826.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCVGSRVLESSP
                     AQMTAAVDVSKAGISKTFTTRNQLTRNQSILMHLVDGPFKKLIGGWKFTPLSPEACRI
                     EFQLDFEFTNKLIELAFGRIFKELASNMVQAFTVRAKEVYRAG"
     gene            3254..3736
                     /gene="smpB"
                     /locus_tag="OPY25_004387"
     CDS             3254..3736
                     /gene="smpB"
                     /locus_tag="OPY25_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCS0929827.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKNAGR
                     "
BASE COUNT         1086 a         1032 c          976 g          934 t
ORIGIN      
        1 tacagtcatg gtttttcata caggaaaaca gctatgttgg cgcaactgac catcagcaat
       61 tttgctatcg ttcgtgagct tgagatcgat tttcagagcg gaatgaccgt cattactggt
      121 gaaaccggcg cgggtaaatc tattgcgatt gatgccctgg gtctgtgtct gggcggtcgc
      181 gctgaggccg atatggtccg taccggagcg acccgcgccg atttgtgtgc ccgctttgcg
      241 ctgaaagaca cgcctgcggc attgcgctgg ctggaagaaa accagcttga agaaggtcgc
      301 gaatgcttac ttcgccgcgt tatcagcagc gatggccgct cacggggctt tattaacggc
      361 accgctgtgc ccctatctca attgcgcgag ctcggtcagt tgctgattca aattcatggt
      421 caacatacgc accagcagct gaccaaaccc gaacagcaaa aatcgctgct ggatagctat
      481 gccaacgaag ccgctttagc gcagcagatg gctgcccact accaattatg gcatcaaagc
      541 tgccgcgatc tcgcccatca ccagcaacaa agtcaggaac gcgccgcgcg cgcggaactg
      601 ctgcaatatc agttaaaaga gttgaacgac tttaatccgc aggccggcga attcgagcaa
      661 attgacgaag agtacaaacg gctggccaac agcgggcagt tgcttacgac cagccagaac
      721 gctctggcgc tactcgcgga cggcgaagac gttaacctgc aaagccagtt atatagcgca
      781 aaacaactgg ttagcgagct ggtgggtatg gacagcaagc tttccggcat cctggatatg
      841 ctggaagaag ccactatcca actcaccgaa gccagcgatg aattacgcca ctattgcgag
      901 cgtctggatt tagaccccaa tcgcctgttt gagcttgaac agcgcatcgc taaacaaatt
      961 tcgctggcgc gaaaacatca cgtcagcccg gaagcgctgc cgcagcttta tcagtcactg
     1021 ctcgaagaac agcagcagct cgacgatcag gccgattcgc tggaaacgct gacgctggcg
     1081 gttaataagc atcaccaaca agcgctggaa acggcgcaag cgctgcatca acagcgtcag
     1141 ttttacgccc aggagctggg gcagttgatc actgaaagta tgcatttact ttcgatgccg
     1201 cacggtctgt ttactatcga cgtgaaattt gatgagcatc atctgagcaa cgacggcgcc
     1261 gatcgcgtgg agtttaaagt gacgacaaac ccgggtcagc cgctgcagcc tatcgctaaa
     1321 gtcgcgtctg gcggtgaact gtcgcgcatt gcgctggcta ttcaggtgat taccgcgcgc
     1381 aaaatggaaa cgccggcgct aatttttgac gaggttgatg ttggcatcag cggcccaacc
     1441 gccgccgtgg tcggtaaact cctgcgtcag cttggcgaat ccactcaggt gatgtgcgtc
     1501 actcacctac cacaggtagc cgggtgcggt caccagcact tctttgtcag taaagaaaca
     1561 gacggggcaa tgaccgaaac ccatatgcaa cctttggata aacgtgcgcg tttacaggaa
     1621 ctggcccgcc tgttgggagg aagtgaagtt acgcgtaata cgctggcaaa cgcaaaagaa
     1681 ctgctggcgg cgtaaacttt tttatctccc gaaggtctga gttcacaaca aaaacgccgt
     1741 aagacccgac agcaaaaggt tttaaagtga tgaaaggtct attatcatcg gcatattaat
     1801 atgagccacg tactgctcag gcccgaaaag gaacccaatc actatgcgct gtaaaacgct
     1861 gactgctgcc gcagcagtac tcctgatgtt gaccgcaggc tgttccactc tggagcgagt
     1921 ggtttaccga cctgacatca atcaggggaa ctatcttaca cctacggatg tcgccaaagt
     1981 gcgtgttggt atgacgcaac aacaggttgc gtatgcttta ggcacgccga tgatgaccga
     2041 tccttttggt acgaacacct ggttttatgt cttccgccag cagccaggac atgagaacgt
     2101 gacgcagcag actctgacgc tcacctttaa cagcagcggc gtgttaacca atattgataa
     2161 caaaccggcg ttgacgaagt aattttgtga taccgcctga tgaggttacg ttcatcaggc
     2221 ctgcaaacct ctcccccgcc atttggtacg aatttgcctg atggcgctac gtttatctgg
     2281 cttacaggca cgcctgtgct tcaggtgtgg tacggctttc acaccgttat ccggcaaaag
     2341 aggctaatta tctgccagcc gatttttcgg cacgctggcg gcgtaatgct tttggatcgg
     2401 cgattaaggg acggtaaatt tcaacccgat cgccatcctg caccgtatcg gtgagtttta
     2461 ccggacgact gtagatacct actttatttt tcgccagatc gatatccgtg cgcaattcca
     2521 gcaagccgga agcgcgaatc gcctcttcga ccgtcgcgcc ctcctccagc gttacgcgct
     2581 gcaaatactg cttttccggc agcgcataag ccacttcaac cacaagttta tccggcacgg
     2641 taaacctctt tggcgcgaac cgtaaacgcc tgcaccatgt tggacgctaa ctctttgaat
     2701 atacgaccaa acgccagctc aatgagttta ttggtaaact caaaatcaag ctgaaactca
     2761 atgcggcacg cctcggggct gagcggggta aatttccagc cgccgatcag ctttttaaag
     2821 gggccatcca ccagatgcat cagaatactc tggttacgcg ttagctgatt acgcgtcgta
     2881 aacgtcttgc tgatacccgc cttcgacacg tcaacagccg ccgtcatctg tgctggcgat
     2941 gactccagga cacgactgcc aacacaccca ggcaaaaact ggggatacga ttgcacgtca
     3001 ttcactaact gatacatctg ttccgcactg taggggacta aagcagtccg actaatctga
     3061 ggcatagcaa ttcccatcaa cataaatcgt gtaaataata ccacttatca gcgagtaaaa
     3121 aaaatgctgt ccccaaccgt catgccttaa ttgtgcgtgc atagcccaac tcatgctaag
     3181 atagattttt gcacctcatc aggacgtaat ggggtgtttt cgatatcaga ttacctatga
     3241 attcacgaca cttatgacga agaaaaaagc acataaaccg ggctcagcca ccatcgcgct
     3301 gaataagcgc gcccggcacg aatactttat cgaagaagag ttcgaggctg gtctcgccct
     3361 gcaaggctgg gaagtaaaat ctctgcgcgc aggaaaagcc aatatcggcg acagttacgt
     3421 tatcctcaaa gatggcgagg cctggctgtt tggcgcaaac tttacgccga tggcggtcgc
     3481 ctcgacacat gtcgtatgcg acccaacccg aacccgcaaa ctgttgttaa atcagcgtga
     3541 gcttgattcg ctgtatggcc gtattaatcg tgaaggttat actgtcgtcg cgctttctct
     3601 gtactggaaa aatgcctggt gcaaagtgaa gatcggcgtg gcgaaaggta aaaaacaaca
     3661 tgataaacgt tccgatctta aagaacgtga gtggcaactg gataaagcac gcattatgaa
     3721 aaatgcaggc cgataataga cattttttgt gaccagcttc tcagtatgaa gctggtcaat
     3781 gttcatatct catgcatgcc tcgaaaatat attctctgtg tctgacgctt atcaatagca
     3841 ataaatacca caccacaaca agaatatatt ctttgtttaa aaaattttta tagcctaata
     3901 acacaatact tcaaatgatt tttataaaat ttaatattgc tgaatacctt cacaaaaagt
     3961 attgttttta tgttaaaaga gaaaaagaag aaaaaattaa aattcattat aaaacataaa
     4021 gataaata
//
LOCUS       DAJVKX010000224         4000 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.224, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000224 DAJVKX010000000
VERSION     DAJVKX010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4000
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.224"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(269..1834)
                     /gene="ahpF"
                     /locus_tag="OPY25_004388"
     CDS             complement(269..1834)
                     /gene="ahpF"
                     /locus_tag="OPY25_004388"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCS0929828.1"
                     /translation="MLDTNMKTQLRAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNTLPVRKPSFLITNPGSQQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRDIDGDFEFETYYSLSCHNCPDVVQALNLMAVLNPRIKHTAIDGGTFQ
                     NEITERNVMGVPAVFVNGKEFGQGRMTLTEIVAKVDTGAEKRAAEALNKRDAYDVLIV
                     GSGPAGAAAAVYSARKGIRTGLMGERFGGQVLDTVDIENYISVPKTEGQKLAGALKAH
                     VSDYDVDVIDSQSASKLVPAATEGGLHQIETASGAVLKARSIIIATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKVRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHSVALAGIFVQIG
                     LLPNTHWLEGVLERNRMGEIIIDAKCETSVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKIA"
     gene            complement(2076..2639)
                     /gene="ahpC"
                     /locus_tag="OPY25_004389"
     CDS             complement(2076..2639)
                     /gene="ahpC"
                     /locus_tag="OPY25_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HCS0929829.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEVTEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYSVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAA
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            3079..3825
                     /gene="dsbG"
                     /locus_tag="OPY25_004390"
     CDS             3079..3825
                     /gene="dsbG"
                     /locus_tag="OPY25_004390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HCS0929830.1"
                     /translation="MIKRTLLLAMLPILAHAEELPALVKAIEKQSITILKSFEAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNALIEKEIYAPAGREMWQKME
                     KASWILDGKKDAPVVLYVFADPFCPYCKQFWQQARPWVESGKVQLRTLLVGVIKPESP
                     ATAAAILAAKNPAKTWHDYEASAGKMKLEVPASIPPAQMKVINQNQQLMDDLGANATP
                     AIYYMNKDKILQQVVGLPEKAQLDAMMGQP"
BASE COUNT          978 a         1067 c          992 g          963 t
ORIGIN      
        1 cagaccgcaa gatgttttaa caaatcaaaa ggggttttaa taactggctt aaagctgaaa
       61 gctttccgga acccccagcc tagctggggg ttttccatag acaaaaaacc gtctgttatt
      121 aacagacggt ttcagagtat tgataatgaa gaacgtgttt tacccggtgg cgttccccag
      181 gcataaacac cgcaggcccg aatagcttac actatcgggc catttacgat ggccagttaa
      241 ctggccttgc aggtgtgctt acttcttttt atgcgatttt ggtgcgaatc agataatcaa
      301 aggcgctcaa cgaggctttc gccccttcgc ctgtggcgat gataatctgt ttgtaaggaa
      361 cggtggtgca atcgcctgcg gcgaagacgc ccttaacgct ggtttcacat ttggcgtcaa
      421 taatgatctc gcccatgcgg ttacgctcaa gcacgccttc cagccagtgg gtattcggca
      481 aaagaccaat ctgcacaaaa attcctgcca gcgcgacgct atgaatatcg ccgctgacac
      541 ggtcacgata ctccagtccc accactttcg aaccgtcgcc cttcacttct gtcgtttgcg
      601 cattcaaaat gatatcgaca tttttcaggc tacgcacttt gtcctgtagc acctgatccg
      661 ccttcatctc cggcgcgaac tccagcaacg taacatgttc tacaatacct gccagatcga
      721 tagccgcttc gacgccggag ttgccgccgc cgatgaccgc cacacgcttg cctttaaata
      781 acggaccgtc gcagtgcggg caataggtga cgcctttggt gcgatactga tcctcgcccg
      841 gcacattcat attgcgccat ttcgcgccgg tggcgatgat gatactgcgc gctttcaaga
      901 ctgcgccgga cgccgtttca atctgatgca ggccgccttc tgtcgctgcc ggaaccagtt
      961 tacttgcgct ctggctgtcg ataacgtcaa cgtcgtaatc gctgacatgc gctttcagcg
     1021 cgcccgccag tttctggcct tcggttttcg gcaccgagat atagttttcg atatccacgg
     1081 tatccagcac ctgaccgccg aagcgctcgc ccatcagacc ggtacggatg cctttgcgcg
     1141 ccgagtagac cgccgccgcc gcgcccgccg ggccggagcc gacaatcagc acgtcatacg
     1201 catcgcgttt gttcagcgct tccgccgcac gtttttctgc gccagtatcc actttagcga
     1261 caatctcggt cagagtcata cgtccctggc cgaactcttt accgttgaca aacaccgccg
     1321 gaacgcccat cacgttacgt tcggtgattt cgttctggaa ggtgccgcca tcaattgccg
     1381 tatgtttaat acgcgggttc agcaccgcca tcaggttcag cgcctgcact acgtccgggc
     1441 agttatggca ggagagtgaa taataagttt cgaattcaaa atcgccgtca atatcgcgaa
     1501 tctgctccag cagcgactgc gcttcttttg acggatgacc gccggtccac agcaacgcca
     1561 aaaccagcga ggtaaattcg tggcccagcg gagaaccggc aaagcgcggc ccctgctgag
     1621 agcctggatt cgtaatcagg aaagacggct tgcgcaccgg cagagtattg tcttctttaa
     1681 atgtgacttt gtcggacagc tcggcgattt cagccagcag ttccttgatt tccgccgatt
     1741 tagcgctgtc atccagcgtg gcaatcagct caacaggttt ggtcagtttc tcaaggtaag
     1801 ccctgagctg ggttttcata tttgtgtcga gcattcttct tccctctctg aaaacatcat
     1861 catgcaagcc gacttcgcgg gactgcatta atgcaacttg cgtcatggtg ctgaaatgaa
     1921 atgggcgcgg atgcgcccat gactgaaaca atttccaaag tatttcacgt cagagtaagg
     1981 cggctagcct gagaatcccc gggagcttac tgaagtaagt gaccggggtg agcaggcaac
     2041 gccaacgcag ctatggcgtg aaagacgacg gaaatttaga ttttaccgac caggtctaag
     2101 gatggagcca gagtcgcttc accttctttc catttcgccg ggcatacttc gcctgggtga
     2161 gcggcaacat actgtgctgc tttaatttta cgcagcaggt cagacgcgtc acggccgata
     2221 ccttcagcgg taacttcgat cgcctgaatg ataccctgcg ggtcaacaac aaaggtcgca
     2281 cggtctgcca ggccttcatc ttcacgcatg ttgtcgaagt tacgggtcag ggcgccagtc
     2341 gggtcgccga tcatcgcata tttgattttt gcgatagttt cagagctgct gtgccatgct
     2401 ttgtgcgtaa agtgagtatc ggttgagacg gaataaacgt ctacgcccag cttctgcagt
     2461 tcttcgtaat ggtcggcaac gtcacccagt tcagtcgggc aaacaaaggt aaaatcggcc
     2521 gggtagaaga agaagacgct ccagcggcct tcggtatctt tctcggtgac ttcaatgaat
     2581 tcaccgtttt tgaacgcctg gtttttgaaa ggtttgattt tggtgttaat taaggacatc
     2641 tatacttcct ccgtgttttc gttgaggagt aagttaacga aattttgctg attcggctaa
     2701 tgcgtttcca ttatcaaatc aataagcgtt aactaacaac ccgattcggg cgacattgtg
     2761 aacactgcgc cctgtcagcc atctaaagta aaaaggccgc ctgacaggcg gccccattac
     2821 ctgaactacc cgtaggtaac ttcagagcca gtacgactcg tcttgcaaat ggcaggcgta
     2881 ttgcctgcca ctcgaaatcc atagcgtata tgctggctaa gtgttgcgct ctacattacc
     2941 ttaacaaagg ctgtaacagc gaaaaggatt acatcacccc agcacagaaa gggcaatcct
     3001 ggcacgccag ctcttaccta tgtctgcgat aggcatcatc attaatactc ttttcgcttt
     3061 gatattaaaa agaaaaatat gattaaacgt acattgctgc ttgctatgct gcccattctc
     3121 gcccacgcgg aagaactgcc tgcgctggtt aaagccattg aaaaacagag cataacaatc
     3181 ctgaaatcct tcgaggcgcc ggggggcatg aagggctatc tcggaaagta tcaggatatg
     3241 ggcgtcacga tttacctgac gccggacggt aaacacgcga tttccggcta tatgtataat
     3301 gaaaaaggtg aaaatcttag caacgccctg atagaaaaag agatctatgc gccagccgga
     3361 cgtgaaatgt ggcagaaaat ggaaaaagcg tcatggatac tcgacggtaa aaaagacgcg
     3421 ccggtggtgc tgtatgtctt tgccgatcct ttctgcccct attgtaagca gttttggcaa
     3481 caagctcgtc cgtgggtcga atccggcaag gtacaattac gcacattact ggtcggcgtg
     3541 attaaaccgg aaagcccggc cacagccgca gcgattttag ccgcgaaaaa cccggcgaaa
     3601 acctggcatg actatgaagc ctccgcagga aagatgaagc tggaggttcc tgcgtccatc
     3661 cccccggcgc agatgaaagt cattaatcag aatcagcagt taatggacga tcttggcgct
     3721 aacgcgacgc cagcaattta ttacatgaat aaagataaga ttttgcaaca ggttgttggt
     3781 ttaccggaaa aagcgcaact ggacgccatg atggggcagc cttaacgcag aaattagcaa
     3841 ggcagaagct taaccgtacc acgcccgaca gcgctacgtt tgtcgggcca accacctccc
     3901 ggtattaacg cgacgccaga ccaaaatgtc atccggcaca gcctttttag gctaacggcg
     3961 tgattatatc agggtacgtt atgtccgcct ttaccgtaat
//
LOCUS       DAJVKX010000225         3980 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.225, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000225 DAJVKX010000000
VERSION     DAJVKX010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3980
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.225"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(46..789)
                     /locus_tag="OPY25_004391"
     CDS             complement(46..789)
                     /locus_tag="OPY25_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCS0929831.1"
                     /translation="MSQNNYLIDKRVILDCERMTLSCAGELITISESERSLLITFYEG
                     LFKKDDLINYVWGRKGVVVSDASYYKLINQLRGSFDKIGLKGESVVTRPRVGVLLSVS
                     IEPLSDEAQDMPLPAVAETELSTVEVRHDDTIIPPIPGAVNRKDWLYFCLAALLMFFM
                     IYKVKGENIDYFTLNGSYDGYTFYSVGHDKTHLADIIEAYSEMSNEIHKQNGKIIYYI
                     RVPNTNIFVQCLNQLDIAEPKCISIKERY"
     gene            complement(889..2463)
                     /locus_tag="OPY25_004392"
     CDS             complement(889..2463)
                     /locus_tag="OPY25_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic diguanylate phosphodiesterase"
                     /protein_id="HCS0929832.1"
                     /translation="MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLR
                     FSADISAASWQVAGKAARLAESSCTDTLKELSRTRAFTPYVRDIGFLENGDITCSFVT
                     GTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
                     YVQELMEILAAERASAFSLIFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPF
                     STLSAYWLQNLFIFIPLSLCLSVGMILFYRRWYLKRLSLAREISRGITHNEFTVHYQP
                     VFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPLSRHLFELIAHDVIN
                     WTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEK
                     LSTLREKGVLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTII
                     TLSQRLGLNVVAEGVSTQHQLRYILSHGVGFVQGFLYARPMGTNDFMSWLGKSAQRQN
                     GLLKGESGSASDLVAE"
     gene            complement(2975..3276)
                     /locus_tag="OPY25_004393"
                     /pseudo
     CDS             complement(2975..3276)
                     /locus_tag="OPY25_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459337.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3249..3971)
                     /locus_tag="OPY25_004394"
     CDS             complement(3249..3971)
                     /locus_tag="OPY25_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004244017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929833.1"
                     /translation="MFLLDKRVVFDSTKMTLSHGNEIIRISEADTHLLLAFWHGLYKK
                     EDIIHFVWENRGGCVSESSYYKLINQMRNDFSSIGLQLSGIVTRPRVGVSLSVAIEPI
                     KKITSLKVSDENVKGPSTREKIFYKIKRHSVFVVLTGAILLALFYGVFTIYKTPVRNS
                     PDSFFTYLGEYNDYAIYKTKEDKVTLSEVVFAFNSLKIKIYRQNGRHLYYIREPNMNI
                     FLQCLNPVEMAVPKCITVKERY"
BASE COUNT         1208 a          909 c          777 g         1086 t
ORIGIN      
        1 ccatcagtac gactgaaaca gccaacatac caagcgtcgc cacgcttaat aacgttcttt
       61 tatggaaatg catttcggct ccgctatatc aagttggtta agacactgga caaaaatatt
      121 tgtattagga acgcgaatgt aataaatgat ttttccgttt tgtttatgta tttcattact
      181 catctcagag tacgcttcaa tgatatccgc cagatgggtt ttatcatgcc cgacactata
      241 aaaagtgtat ccatcatacg aaccattgag ggtaaaataa tcaatatttt cacccttaac
      301 tttataaatc ataaaaaaca tcagaagcgc ggccaggcaa aagtagagcc aatcttttct
      361 attcacagcg cccggtattg ggggaataat agtatcatcg tgccgcactt caaccgtcga
      421 taattctgtt tcagcaacag caggcaacgg catatcttgc gcctcatcac tcaacggttc
      481 aatggaaact gagagtaaaa cacccacgcg agggcgagtc acaacagact cccccttaag
      541 accaatttta tcaaatgatc ctcgtagctg gttaatcagt ttataataac tggcatcaga
      601 gaccacaaca cctttgcgcc cccagacata gttaattaaa tcatcttttt taaaaaggcc
      661 ttcataaaaa gtgataagca aactgcgttc cgattcagat atcgttatca actctccggc
      721 gcaggaaagc gtcattcgtt cacaatcaag aataaccctt ttgtcaatca gataattgtt
      781 ctgactcata aaaatatccg ccccagtgct atcacgtttc ttcacggcat aaacatatta
      841 ctaggatata tcgtgctatt gaattttttt ccgtagcgag ttcctgcatt attcagccac
      901 cagatcgctc gcggatccgc tttccccctt gagcaaacca ttttgccgct gggctgactt
      961 gccaagccaa ctcataaagt cattagtccc catcggcctg gcataaagaa atccctgaac
     1021 gaatcctacc ccgtggctta agatgtaacg caattggtgc tgggtactga ccccttcggc
     1081 aaccacattg agtcccagtc gctgactcag cgtaatgata gtatccagga caggaacatc
     1141 atcgctgctg gtatcaatgg tatcgataaa cgttctgtct attttaagag agtctacagg
     1201 taattgctgg agataggaga gggagcaata gccggtccca aaatcatcaa tcgctattaa
     1261 cacgcctttt tcacggagcg ttgaaagttt ttctgcgacc tgtgaaggtt ctacaatcag
     1321 gctacgttcg gtgagctcca acataagcgt tatcgttccc aaacgagtcc tgagcgcctc
     1381 tatatcttgt ataaaaccgt catccataag atgcgcaggc gatatattta cgctgatata
     1441 gaaatcatcc ggtacagtcc agtttatcac gtcatgagca atcagttcga acagatgacg
     1501 agagagtgga ataatcatgc cttcattttc tgcggcggta ataaaaatat cgggagttat
     1561 aaaacggcca tccggttgcg gccagcgcat tagcgcctcc acgccgccgc aactaccgtg
     1621 tttaacatta aaaacaggtt gataatgtac cgtaaattca ttgtgcgtta ttcccctgga
     1681 aatctcccgg gccagagata agcgttttaa ataccagcgc ctgtagaaca atatcatccc
     1741 tacagaaaga cataatgaca gcggaataaa aataaaaagg ttttgtaacc agtatgccga
     1801 taacgttgag aaaggggttc gcaccatcag ctggatagtg tgatcggttg aggtgaaccg
     1861 ctgcgttaaa aacgccttac cgcgcaacgt cgcagcgctg gtaatcgcct ctcctgcgcc
     1921 gaatatcagg ctaaaggctg atgctctttc tgcagccaat atctccatga gctcctggac
     1981 atactgcgaa tccacaatga cgaaagccgc tttatccgct gctacttttt tcacatacac
     2041 cacaacaagg cgatcgggtc cttcggccat actaccgata gatcgcaacc accgttccgg
     2101 ataagaagca ggtaaagaaa gccctgccag ccgggaaaaa tgatagcgtt cggttcctgt
     2161 gacaaaggag caagtgatat caccattttc cagaaaccca atgtcacgga cataaggagt
     2221 gaaggcccgc gttctggaca gttctttcag cgtgtcagta caggaactct cagccagtct
     2281 ggcggctttt ccggcgactt gccaggaggc ggcggatata tccgcgctaa accgcagcag
     2341 cgtattggcg ctgacggcga tatctcgttt tagctggaag atacccgcga gtaaccccac
     2401 caatatcatt acgatcagtg gaacggcaat aaacaacatc agaaatagct ttcttacttt
     2461 caaatcattg ccctcttacc ggccttcctt ttgccactgt acgcttttat aggataacta
     2521 aagtaacatt aatagagaaa agaaatattg agagataggt tatacgttct taatgatagc
     2581 aagatggcac tccctgtgcc gaaaacagac aagagaatat caatacccaa caggtgcagg
     2641 atactatcgt taaaatgagc gataacagat atctaaataa agacgcattc aatatgttag
     2701 cctgatgcca ggttcactgc ctgatgagac ataaccatca cggaacgaat tcccatcaat
     2761 acagggatta ttggttacaa ctcaacgtta ctactggtgg tacacacatt atacaaatgc
     2821 cgattaagcg aaaacatgta ggtgtttttc ccaattttga caatttttag ctcattaatc
     2881 gtaccgggtt gtaacaacct caaccaggaa aataaatcgc cagcagtatc agactcaaag
     2941 gtcttaactg aattgacttt aaaagtaaat gttttcatac ccgttctgcg cagtttgctg
     3001 atgcagatgt cacgaaaaaa aaagccgttt ctctttcgta tcggtagtaa catcgtagtg
     3061 tagggtaatc ctgccggatt taagatccag cacaagtcca ccatccatgt acaattttcg
     3121 tggttcaata tacgcttctg attttgtcgt gcatataaga ttattggttc tataagagtc
     3181 acgatttacc cactcaagcg ctattaccga tccgattgcg acaatggcga taaatattac
     3241 aaatataatc agtaacgttc ttttactgta atacattttg gcaccgccat ttcaacagga
     3301 ttcaagcatt gcagaaaaat attcatattt ggctccctga tataataaag atggcgtcca
     3361 ttttgccggt aaattttaat ttttagagag ttaaaagcaa aaactacttc acttaatgtg
     3421 accttatcct cttttgtttt atagattgca taatcgttat attcgccaag atatgtaaaa
     3481 aaactatcag ggctgttacg aacaggcgtt ttatagatag taaatacacc atagaacaat
     3541 gccagaagaa tggctcctgt taatactaca aatacgctgt gacgtttaat tttgtaaaat
     3601 attttctccc gagtcgaggg gcctttaacg ttttcatcac tcacctttag ggaggtgatt
     3661 ttttttatag gttcaatggc aacagacagc gacaccccca cccgagggcg agttacgatg
     3721 ccagatagct gtagaccgat gctactaaaa tcatttctca tttgattaat gagtttatag
     3781 taacttgatt ctgagacgca gcctccacga ttttcccaaa caaaatgaat aatatcttct
     3841 tttttgtaaa gaccatgcca aaaagcaaga agcagatggg tatcagcttc tgatattctg
     3901 attatctcat taccatgaga taaggtcatc ttcgtactat caaatacaac acgcttatca
     3961 agtaaaaata tgctttcatt
//
LOCUS       DAJVKX010000226         3886 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.226, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000226 DAJVKX010000000
VERSION     DAJVKX010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3886
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.226"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            66..638
                     /locus_tag="OPY25_004395"
     CDS             66..638
                     /locus_tag="OPY25_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCS0929834.1"
                     /translation="MQIGYIRVSTNDQNTDLQRNALNCAGCELIFEDKISGTKSARPG
                     LKKLLRTLSEGDTLVVWKLDRLGRSMKHLITLIEELREKGVNFRSLTDSIDTSTPMGR
                     FFFHVMGALAEMERELIVERTLAGLEAARAQGRIGGRRPKLTKEQHEQIARLIKNGYS
                     RKQLAIIYDIGISTIYRYHPVEELQTQAEL"
     gene            919..2301
                     /locus_tag="OPY25_004396"
     CDS             919..2301
                     /locus_tag="OPY25_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCS0929835.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWA
                     ITGVGILLLAFAMLILTRIRSELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPALRLFGDGNTWQAIVGASVLLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGAFIVLAIMMFKLDTFTLDFTGVELGIPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARAKNKRDVGRATLLAVLAALGIYLLVTLLSLGVLARPELAEMRNPSMAGLMVKM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAAAYKSFPGIFARQNAQGAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHRAVGIG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARRTHKHDNVLNRQEVVLIGLLLVA
                     AVPATWMLVG"
     gene            complement(2363..2698)
                     /locus_tag="OPY25_004397"
     CDS             complement(2363..2698)
                     /locus_tag="OPY25_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HCS0929836.1"
                     /translation="MGLVIKAALGALVVVLIGLLSKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIDAMRTTIVFSMWSIIPYFIYLATLWYFSGVMRLPVALGGAVVCWGLSAWL
                     LIFCWIKWH"
     gene            2825..3556
                     /gene="rstA"
                     /locus_tag="OPY25_004398"
     CDS             2825..3556
                     /gene="rstA"
                     /locus_tag="OPY25_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HCS0929837.1"
                     /translation="MNRIVFVEDDAEVGSLIAAYLAKHDIDVIVEPRGDRAEDLILIT
                     QPDLVLLDIMLPGKDGMTICRDLRHRWQGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQSEQTQQAKSLQESALTPHKALRFGALTIDPLNRAVQLNGDFI
                     SLSTADFELLWELATHAGQIMDRDALLKTLRGVNYDGLDRSVDVAISRLRKKLLDSAA
                     EPYRIKTIRNKGYLFAPHAWDETTG"
     gene            complement(3621..>3886)
                     /locus_tag="OPY25_004399"
     CDS             complement(3621..>3886)
                     /locus_tag="OPY25_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929838.1"
                     /translation="AYIYGEYVCYYIFMVVICLISQFAKKDGNIAADRHSVINFVNWL
                     RVFFNLIFLSEKDVIMNRNAEKTVIKGLFRLIKIALMYTVSVF"
BASE COUNT          938 a          954 c          960 g         1034 t
ORIGIN      
        1 gttttcgtct taactcccac ctataccagc tatgtatttt taacaaaaca aagaggatat
       61 ttttcatgca aattggctac attcgtgtgt caacaaatga ccagaataca gatttacaac
      121 gaaacgcact gaactgcgca ggatgtgaac tgatttttga ggataaaatc agcggaacaa
      181 agtcagcccg accgggattg aaaaagctgc tcagaacgtt atcagaagga gatacgctcg
      241 ttgtctggaa gctggacagg ctgggcagaa gcatgaaaca cctcatcact cttattgagg
      301 aactgcggga aaaaggggtt aacttccgta gtcttacaga cagcattgat acgtcaacac
      361 ccatgggacg tttctttttt cacgtcatgg gggctttagc ggaaatggag cgtgaattaa
      421 tagttgaacg aacactggcc ggacttgaag cagcacgtgc acaggggcgt attggtggac
      481 gtcgtccgaa actgacaaaa gagcaacatg aacaaatagc aaggctgatc aaaaatggct
      541 atagcaggaa acagttggca attatttacg atatcggtat atcgacgatt tatcgttatc
      601 accctgtaga ggaacttcaa actcaagctg agttgtaatt ctttttctga tattgaaatg
      661 ccgcggcgat gtaatttatc tcacggaaat aggtacgttt atcgcgcggc gcatcaatca
      721 ggctttctcg cgggatgcca gttccgtcaa atatcgcgat gaatctcact tttcgctttt
      781 ttggcgataa atcttatcca ggccgttgca tgcggtccct tctctccgta aaatcccgcg
      841 ccttagtggc tttcaccatt tttatgcgtt ttgccataat aattattctt ccaatttcat
      901 ttttatagct ggataccaat ggaaaaaaaa ctgggactga gcgcgctgac cgcgctggtt
      961 ttaagctcaa tgcttggcgc aggtgttttc agtctgcccc agaatatggc cgccgttgcc
     1021 agtccggctg cgttgttaat tggctgggcc attaccggcg tggggatact cctactggca
     1081 ttcgccatgt taatccttac gcgcattcgc tccgagcttg acggcggcat ctttacttac
     1141 gcccgcgaag gcttcggcga actgattggc ttttgttctg cctggggcta ttggctgtgc
     1201 gcggtcatcg ccaacgtatc ctatttggtt atcgtctttt cagcgctgag tttctttacc
     1261 gatacgcctg ccctgcgtct gtttggcgac ggtaatacct ggcaggctat tgtcggcgct
     1321 tcagtcctgc tctggattgt ccatttcctc atcctgcgcg gcgtacaaac ggcagccagc
     1381 atcaatctgg tcgcgactct ggcgaaactg ttaccgctcg gcgcgtttat tgtgctggct
     1441 atcatgatgt tcaaactgga taccttcaca ctggacttca ccggtgttga gctcggtatt
     1501 cccgtatggg aacaggtcaa gaacaccatg cttattacgc tgtgggtgtt tattggcgtt
     1561 gaaggcgccg tcgtcgtctc ggcccgagcg aaaaataaac gcgatgtagg ccgcgccacg
     1621 ctactggcgg tactcgcagc gctgggaata tatctcctgg tcacgctgct ttctcttggc
     1681 gttcttgcgc gtccggaact ggcggagatg cgcaacccgt cgatggccgg tctgatggtg
     1741 aaaatgatgg ggccgtgggg agaaattatt attgcagcgg gactgattgt gtctgtctgc
     1801 ggggcttatc taagctggac tatcatggcg gcagaggtgc cgtttctggc ggcagcctat
     1861 aaatccttcc cgggcatctt cgcgcgacaa aatgcgcaag gcgcgccttc tgcgtcgtta
     1921 tggctcacca acatctgtgt gcaaatctgt ctggtgctga tctggctgac cggttcggac
     1981 tacaacacac tattgacgat tgcgtcagaa atgattctgg tgccctactt tctggtcggc
     2041 gcatttctgc tgaagattgc aacgcgtccc ctccatcggg cggtcggtat cggagcctgt
     2101 atttatggct tatggttatt atatgcgtcg ggccctatgc acctgctgct gtccgtcgta
     2161 ctgtacgcgc ctggattact ggttttcctg tatgcgcgtc ggacgcacaa gcatgacaat
     2221 gtattaaatc gtcaggaagt cgtgctgatt ggtttattgc tggtcgcggc ggttccggct
     2281 acgtggatgc tggtgggtta acaacctccc tatcgtaata tccgtctgta ttacgatggg
     2341 gaaaccacgg tctttgccaa tattaatgcc atttaatcca gcaaaaaatc agcagccacg
     2401 cgcttagccc ccagcagacc accgcaccgc caagcgcgac gggcaggcgc atcacgccgc
     2461 tgaaatacca tagcgttgca agataaatga aataaggaat gatcgaccac atgctaaaga
     2521 cgatggtggt acgcatcgcg tcgatgcccc gctcgctagc cacgatatag tgcgcgataa
     2581 gcgcaaacgt tggaaacaga ggaattaatc cggcgatata ataatttttt gtttttgaca
     2641 gcagaccaat caatacgacg accagcgccc ccagggcagc tttaatcacg agtcccatta
     2701 ccttgcctta acatgctaat aacaacagca tgtagcataa cggaaccgct ctcgtttaga
     2761 aaagatttat ggaagggaaa acagaggagg tgtatgttgg cgttttctat tctccattta
     2821 taatatgaac cgcattgtat ttgttgaaga cgacgctgaa gtgggttctc tcattgccgc
     2881 ttatctggcg aaacatgata ttgatgtcat tgttgagccg cgtggtgacc gggcggagga
     2941 tcttatcctc atcactcagc ccgatctggt tttactggat attatgcttc caggtaaaga
     3001 tggcatgacg atatgccgcg atttacgcca ccgctggcaa ggcccgattg tcctgctcac
     3061 ctcgctggac agtgatatga atcatattct ggcgctggag atgggcgcct gcgactacat
     3121 cctcaaaacc acgcctccgg ccgttttgct ggcgcgtctg cgcttacacc tgcggcaaag
     3181 cgaacaaacg caacaggcaa aaagtcttca ggagagcgcg cttacgccgc ataaagcgct
     3241 gcgttttggc gcgttaacca tcgatcccct taaccgggcg gtccagctca atggcgattt
     3301 catatcgctc tccaccgccg attttgaatt gctctgggaa ctggcgacac acgccggaca
     3361 aattatggat cgcgacgcgt tgctaaaaac gctgcgcggc gttaattatg atggtctgga
     3421 tcgcagcgtg gatgtggcga tttcccgcct gcgtaagaaa ctgctggata gcgctgctga
     3481 gccctatcgt ataaagacca ttcgcaataa aggctatctt tttgcccctc atgcctggga
     3541 cgaaacgacg ggataagtga gtcgacagat tttacctgcc tttatcaagt catagtggcg
     3601 atgctcatca ccgccactgt tcaaaaaaca gacaccgtat acatcagtgc tatttttatt
     3661 agtcggaaca gcccctttat taccgttttc tctgcgttgc ggttcatgat tacgtctttt
     3721 tcgctcaaga aaattaaatt aaaaaaaact cgaagccagt tcacaaaatt gataacagaa
     3781 tgtctgtccg ccgctatatt gccatctttt ttcgcaaatt gtgaaatcaa acaaatcaca
     3841 accatgaata tataataaca aacatattca ccataaatat atgcgt
//
LOCUS       DAJVKX010000227         3871 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.227, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000227 DAJVKX010000000
VERSION     DAJVKX010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3871
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.227"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(5..1405)
                     /gene="asnS"
                     /locus_tag="OPY25_004400"
     CDS             complement(5..1405)
                     /gene="asnS"
                     /locus_tag="OPY25_004400"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCS0929839.1"
                     /translation="MSVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEEVLHLTTGCSVVVTGKVVASPGQGQSFEIQATKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAIARLERFVSTDFAQVDYTDAVAILERCGKTFENPVFWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
     gene            complement(1606..2067)
                     /locus_tag="OPY25_004401"
     CDS             complement(1606..2067)
                     /locus_tag="OPY25_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HCS0929840.1"
                     /translation="MKLDAWDKNILTLLQRDNRLSQREIAEQVNLSPSAVNRRIAALE
                     EAGIIKGNVSLVDAGKVGRPVTIVVQVVIENERFNLLEEARQRFVSCPQVQQVYYVTG
                     DFDFLLVLNVRDMAEYETLTRELFFSSGNIKSFKTIVVMQNAKQEMRVLIE"
     gene            2385..3600
                     /gene="dpaL"
                     /locus_tag="OPY25_004402"
                     /pseudo
     CDS             2385..3600
                     /gene="dpaL"
                     /locus_tag="OPY25_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
BASE COUNT         1039 a          918 c          926 g          988 t
ORIGIN      
        1 aaaatcagaa gctggcgttg cgtggggtcc gtgggaacgg aataacatcg cgcacgtttt
       61 gcacacccgt gacgtaagcg ataaggcgtt caaagcccag gccaaagccg gaatgcggta
      121 cagtaccgta gcgacgcaag tcgcgatacc accagtaatc ctctttattc agccccattt
      181 cggccatacg ggcatccagc acatccagac gctcttcacg ctgggaacca ccgatgattt
      241 cgccgattcc cggcgccagc acatccatgg ccgccacggt tttgccatct tcgttaaggc
      301 gcatgtaaaa cgctttaatt tctttcggat agtttttcac cactaccggc gctttgaaat
      361 gctcttccgc cagataacgt tcgtgttcgg aagaaaggtc gacgccccag aacaccgggt
      421 tttcaaatgt cttaccacag cgttccagaa tggcgaccgc atcggtgtaa tccacctgag
      481 caaagtcggt ggagacaaaa cgctccagac gagcgatagc gtctttatcc acgcgttcgg
      541 caaagaactt catgtcatcc gcacgctctt ccagaaccgc cttgaagaca tatttcagca
      601 tggcttccgc cagacgggcg ttgtcttcca gatcggcgaa cgccacttcc ggctccagca
      661 tccagaactc cgccaggtgg cggctggtgt tggaattttc cgcgcggaag gtcggcccaa
      721 aagtatagat tttggacagc gcacaggcat aggtttcacc attgagctgg ccggagacgg
      781 tcaggaatga ttctttgcca aaaaagtctt tgtcaaaatc tactctgccc tggtcgttac
      841 gcggcaggtt ttccagatcc aacgttgaga cgcggaacat ttcgccagcg ccttcggtat
      901 cggaagcggt aatcagcggg gtagagaccc aaaagaaacc ctgctcatcg aagaagcgat
      961 gcagcgcctg cgccagagta tggcggacgc gcgctaccgc gccaatcagg ttggtgcgcg
     1021 ggcgcagatg cgcgacttca cgcagatact caatgctatg gcgttttgcc gccatcgggt
     1081 aggtatccgg atcttccacc cagcctgcga cctctacttt cgtggcctgg atttcgaaac
     1141 tttgcccctg tcccggcgac gcgacaacct tacctgttac taccacggag cagcctgtcg
     1201 tcaggtgtaa tacttcttca ttataattgg gcagagaatt attaatgaca gcctgtacag
     1261 gatcaaagca ggagccgtca taaacggcga ggaaggagat gccagctttt gaatctcggc
     1321 gggtacgcac ccatccgcgc acggtgactt cttggtcaac ggctacgcgg ccctggagta
     1381 cgtcggctac aggcacaacg ctcataatat tctctctagt taatagtcgg aaaaaataaa
     1441 cacttgtcca cccgaaatgg gggtattcct atgttacctg gcatctgcaa tcagacaagc
     1501 agaaatcgca tctggaagca ggttttcaga aagaaacctg taaaaagttc gcacctgctc
     1561 gcgaacaatt gagaatttag gctggttttg taagctttgc gcacgttact cgatcaggac
     1621 gcgcatctct tgcttggcgt tttgcatcac gacaatcgtt ttaaaagact taatattgcc
     1681 tgaggaaaag aaaagctcac gggtaagtgt ttcatattcc gccatgtcac gaacattgag
     1741 caccagtaaa aagtcgaaat cgcccgttac gtagtagacc tgctgcacct gcgggcaact
     1801 gacaaaccgt tgacgagcct cttccagtaa attgaatcgc tcgttttcga tcaccacctg
     1861 caccacaatc gtgaccgggc gtcccacttt gccagcatca acaaggctga cattgccttt
     1921 aattatgccc gcctcctcca gtgccgcgat acgacgattc actgccgaag gtgaaagatt
     1981 gacctgttcg gcgatttccc gctgagaaag acgattatcg cgttgcaata atgtcagaat
     2041 gtttttatcc caggcgtcaa gcttcatatc gcaaataacc tctttaatgt gatgactatc
     2101 actgtgcgca attttgccgc gtccaggccg ttaaaaaaag gtgaaaattg cacgacgatg
     2161 ggcattttcg cgccatttaa cagcaataag catagtacta tcataatcag cggaataaag
     2221 aaaaggacgt aatagatatt gtgcgactct tttatcagta cggtttatta aagtgaggat
     2281 aaccactact acagccacaa aacgcgagtt ctttacttgt ttctactcaa taattgccaa
     2341 aaacatatta tttcaataaa taaactttaa caaaaggtat cattatgcat gagcttatta
     2401 aataccagtt taatacacgt cggaaaaaat atggtacagg agcggcttta agtttgctta
     2461 acggaaatgt tgggcgtgag gtgttagcat ttcataaaaa attacccaat tatgccgtta
     2521 cgccgttaca taatctggcg catctaagcc ggcggcttgg actagggtcc atccatatta
     2581 aagatgagtc ctggcgtttt ggtctgaatg cttttaaagg tctgggcggc tcttatgctg
     2641 taggaaaata tctcgctgat aaattgcaat gtgatattaa ctcgttaagt tttgctgccc
     2701 ttaacactcc tgagattaaa gaaaaaatta aagattgtgt ttttgttacc gcgacggatg
     2761 gcaatcatgg ccgtggtgtg gcgtgggcgg cggagcaatt aggtctaaaa gccgtcgttt
     2821 atatgcctaa gggatcatcg ttaatctggg cagagaatat tcgccatcat ggagctgaat
     2881 gcaccatcac cgatctgaac tacgatgatg cagtgcgact ggcccataga atggcgcaaa
     2941 caaaaggctg ggtgcttttg caggatacag cctggacagg gtatgaagag atcccaacat
     3001 ggattatgca aggctatatg atactagcgg ttgaagctta tgagcagctc gcagaaacaa
     3061 acagtccgtt gccaacccac cttattttac aagcgggggg tgggatcatt tgctggcagt
     3121 gttatgggtt attttgttga aaaaatgcag gaaaataccc ctaatattat tgtggttgag
     3181 ccgcatcagg ccaactgtct ttatcaatcc gcagttatga atgatggtca acctcactgc
     3241 gtcactggcg atatggcgac gataatggcc gggcttgcgt gtggggagcc gaatattatc
     3301 agttggccta ttattcggga caacaccagt tgttttattt ccgctgatga ttgtctggcg
     3361 gctaagggta tgcgcattgc tgccgcgccg cgtccaggca ctgatacgcc ttttatttcc
     3421 ggcgagtccg gagctattgg cgtagggtta ctttatgagt tgatgaacaa tatgcattat
     3481 caggatcttg ctaatcgctt acagcttgat gccaatgctc atgttctgct tattagcacc
     3541 gaaggcgata cgtccccaga tatttatgaa gatatagtct ggaacggacg cagtgcttaa
     3601 acattacgac taaaaaatta gataataaag gcagcatgta aaaaacgcgt tttttatacg
     3661 cataataaac ctaatgcagg aagcaaaact tcataacaat ataccattaa aacggcattt
     3721 agtgagtaag ggatgctcct acccgctgac tttccagttt agtgttgttg gcaaaattca
     3781 ggattacgct gaactggaaa gattatttct gagactgaac gaattaattt aaatccgagg
     3841 tcattatgtt agagcaactt tcacaactct t
//
LOCUS       DAJVKX010000228         3850 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.228, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000228 DAJVKX010000000
VERSION     DAJVKX010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3850
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.228"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            128..673
                     /locus_tag="OPY25_004403"
     CDS             128..673
                     /locus_tag="OPY25_004403"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCS0929841.1"
                     /translation="MIRHIAIFLCSLLMCSTTFADSVTSVSLGALLTALNERMLLMKD
                     VAAYKMKHHLPIEDFTREQNVFAEAEEEAKNNGLDPHSITPFIRSLMDASKAIQYRYL
                     AQWRTGSEPSFPIQTLSVTRQRIRQLDNQMLIIISQRLMVGAFSHEDMVWLRTHFNAP
                     NLNESDISDVLAALSLVRHAR"
     gene            869..1507
                     /gene="leuE"
                     /locus_tag="OPY25_004404"
     CDS             869..1507
                     /gene="leuE"
                     /locus_tag="OPY25_004404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HCS0929842.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGY
                     LAACGVFIGDAILMFLAYAGVATLIKTTPVLFNIVRYLGAFYLLYLGAKILYATLTSK
                     GRAATETVVPFGAIFKRALILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTL
                     EIVSFCYLSFLILSGAFVTHYIGTKKKLAKVGNSLIGLLFVGFAARLATLQS"
     gene            1680..2042
                     /locus_tag="OPY25_004405"
     CDS             1680..2042
                     /locus_tag="OPY25_004405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HCS0929843.1"
                     /translation="MRQIPQNHIHTRSTPFWNKETAPAGIFERHLDKGTRPGVYPRLS
                     VMQGAVKYLGYADEHCSEPEEIMVINAGEFGVFPPEKWHNIEVMTDDTYFNIDFFVAP
                     EVLMEGATSRKVIHAGRE"
     gene            2045..2227
                     /locus_tag="OPY25_004406"
     CDS             2045..2227
                     /locus_tag="OPY25_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HCS0929844.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETEAPMTLLVPEVTAEVVKDLVN
                     TVRSYDTENEHDVCGW"
     gene            2457..3098
                     /locus_tag="OPY25_004407"
     CDS             2457..3098
                     /locus_tag="OPY25_004407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929845.1"
                     /translation="MKLDTRLTSSALTLALAAVVIPFTADWQLPLLNGVVVRWIENGQ
                     ALWLLFGALFTAWYIRPLSRPEGAKQFWLWAVVWWVVLLGRSTSWGRDYFPDEPRMLF
                     RTISVLLIAALVLPVLFFAGLRKEIVRRLRDVPLPLWLFTVTACSYLISDTVEHHRWL
                     SPIFLHNARYTDLIEELYEVPFMIGLFMVTVGFMQQDKQDECTALELTPYHAK"
     gene            3412..3660
                     /locus_tag="OPY25_004408"
     CDS             3412..3660
                     /locus_tag="OPY25_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCS0929846.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTIILGIVGAVVGG
                     WISTFFGFGKVDGFNFGSFAVAVIGAIVVLLIYRKIKS"
BASE COUNT          971 a          797 c          974 g         1108 t
ORIGIN      
        1 aacggcctgt tcttttttct cactccagtt taaacgaata agcattaata cccatctgta
       61 ataattactt aatgttatct taataaaggt aaattactgt cagacctccg taaaaggagg
      121 ttgattaatg attcgtcata tcgccatttt tctttgttct ttattgatgt gcagcaccac
      181 ttttgccgat tcggtaacgt cggtatcgct tggcgcgctc ttaaccgcgc tcaatgaacg
      241 catgttatta atgaaagatg tggctgctta taaaatgaag caccatctgc cgatagagga
      301 tttcacacgt gaacaaaatg tttttgccga ggctgaagaa gaagcgaaaa ataacggtct
      361 ggacccgcat tcgataaccc cttttattcg ttcgctaatg gatgccagta aagcgataca
      421 gtaccgctat ttagcgcagt ggcgaaccgg ctcagaaccc tcctttccga tacaaacctt
      481 gtcggtcacc cggcaacgta ttcgacaact tgataatcaa atgttgatca ttatcagcca
      541 gcgcctgatg gtcggcgctt tcagccatga ggatatggtg tggctgagaa cgcactttaa
      601 tgcgccgaat ctgaatgaga gcgatatcag tgatgtgttg gcagccctat ctttggtgcg
      661 acacgcgcgt taatccccca tgaggaaacg tgggccaata cctggtgatt gcctgcgggg
      721 gcgcgataaa agaacgtttt tgggtgatgg ggatataagc gtggcggaat agcggctgga
      781 gagacgtggt ttcgcttccc atcttccgat gcattcgtta gcatactgtt tcgcagctaa
      841 gcgtaaatgt tttcaggaag aggttaatgt gttcgcggag tatggtgttc tgaattattg
      901 gacgtacctg gtcggggcga tttttatcgt tctggtacca gggccgaata cgctttttgt
      961 gcttaaaaat agcgtgggac gcggggttaa aggaggatat cttgccgcat gtggcgtgtt
     1021 tatcggtgat gcgatattaa tgtttctggc gtatgcgggc gtggcgacgc tgatcaaaac
     1081 aacgccggtt ctgtttaaca ttgttcgcta tctcggcgcg ttttatctgc tctaccttgg
     1141 cgcaaaaatc ctttacgcca ctctgacctc aaaagggcgt gcggcgacgg aaacggtagt
     1201 tccttttggc gctattttta agcgtgcttt aattcttagc ctgacgaatc ctaaagccat
     1261 acttttttat gtttcctttt ttgtgcaatt tattgatgtt actgcgccgc atactggggt
     1321 gtcatttttt attttggcca ccacccttga aatcgtcagt ttttgctatc tgagcttttt
     1381 aattctttct ggcgcttttg taacccacta tattggtacc aaaaagaaac tggcaaaagt
     1441 gggcaattcg ttgattggcc ttcttttcgt cggatttgcc gcccggctgg caacgctcca
     1501 gtcttaaccc cctggacccg tcgtgaacgg cgggtcattg ctctcctttc ggttttattg
     1561 cgtggaaaac agcaaaatag taaccaataa atggtattta aaatgctgtt tttggagcgt
     1621 aaccttttta cgacagcgat gagattatcg ctgagtaacc tgcgggaaga gggaagcaaa
     1681 tgcggcaaat tccacaaaat catatccata cacgttccac gcccttctgg aacaaagaga
     1741 cggcgcctgc cggaattttc gaacgccacc ttgataaggg aacgcgaccc ggcgtttatc
     1801 ctcgcctctc ggtgatgcag ggggcggtca aatatctcgg atacgctgat gaacattgct
     1861 ctgagccgga agagatcatg gtgatcaatg ccggcgagtt tggcgtgttt cctccggaaa
     1921 agtggcacaa tattgaggtc atgacggatg atacctattt taacatcgac ttttttgtcg
     1981 cgccggaagt actgatggaa ggggcgacct cacgaaaagt cattcatgcc gggagagaat
     2041 aataatggga aaagctactt ataccgtcac ggtcacgaat aatagcaacg gcgtctctgt
     2101 ggactatgaa acggaagcac cgatgacgtt gctggtacct gaagttacag cagaagttgt
     2161 gaaggatttg gtcaataccg tgcgttccta cgataccgaa aacgaacacg acgtttgcgg
     2221 ttggtaaaga tgctgtagta tctatttgat ataaaatgat tctttaaatg agaagccgca
     2281 tcgcgcgtcg ccagcgtgat gcggtttttg cgtattgaaa agcgctgttt atttacatca
     2341 gacatgggtt gaaaagaaac attaagaaaa cattaagaat atcgcattgt ttgctaatga
     2401 gagcgtattc ataaaactta tgattgggta ttaaaaacca gaagagtctt atgatcatga
     2461 aactcgatac ccgattaact tcgtcagcac ttactcttgc gcttgccgct gtggtcatcc
     2521 cgtttacggc ggactggcaa ttgcctttgc ttaacggcgt ggtggtccga tggattgaaa
     2581 acggacaagc gttatggtta ctgtttgggg cgctatttac cgcctggtat atacggccac
     2641 tttcccgtcc cgaaggggca aagcagtttt ggctatgggc tgttgtctgg tgggtggtgc
     2701 tgttgggtag aagcaccagt tgggggcgtg actatttccc tgacgagccg cgtatgctgt
     2761 tcagaacgat ttcagtgcta ttaattgctg cgttggtatt gccagtcctg ttttttgccg
     2821 ggctacgtaa ggagattgtt cgtcgtctgc gggacgttcc tctgccattg tggctgttta
     2881 ccgtgacggc atgttcatat ctgatttccg acactgtcga gcatcatcgg tggttgtcgc
     2941 cgatattcct gcataacgct cgttacacag atttgattga agagctttat gaagtgccat
     3001 ttatgatcgg tttgtttatg gtgaccgtgg ggtttatgca gcaggacaag caggatgaat
     3061 gtactgcgct ggagctgacc ccgtatcacg caaaatagcg cggctgaaaa agaccatgaa
     3121 ttcgatatgg gatagatagc agttagcaaa aaaagcccgc actcggtgag gcgggcaaat
     3181 aatactggaa gcaatgtgag caatgtcgta ccgaacaggt gggttataaa ctcaaccact
     3241 cggtattgat aaagataatc gttatcatta atgattgcaa ccctgatatt tatgcgcttt
     3301 tatccacgac gctaaaaggt gatggatatc acaaacttca ctttcctgac gatgtgctat
     3361 tctttttaac ggcaaataaa ccgctaacgt taagacataa gtgaggaaaa aatgggtatt
     3421 ctttcatgga ttatttttgg acttattgcg ggtattttgg ctaagtggat catgccaggt
     3481 aaagatggcg gcggattctt tatgacgatc attctgggga tcgtcggtgc ggtagtcgga
     3541 ggatggatca gtacgttctt tggctttggc aaagtggatg gtttcaactt cggcagcttt
     3601 gcagtcgcgg tgatcggcgc gattgttgtg ctgttaatct acagaaaaat caaaagctaa
     3661 acgcagaact ttcagagata ataaaggcta cgacaggtag cctttattat tgtctatgga
     3721 aaacccccag ctaggctggg ggttccggaa agctttcagc tttaagccag ttattaaaac
     3781 cccttttgat ttgttaaaac atcttgcggt ctggcaactg caaaagttca acaagaaatc
     3841 aaaagggggt
//
LOCUS       DAJVKX010000229         3833 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.229, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000229 DAJVKX010000000
VERSION     DAJVKX010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3833
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.229"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(242..1891)
                     /gene="pgi"
                     /locus_tag="OPY25_004409"
     CDS             complement(242..1891)
                     /gene="pgi"
                     /locus_tag="OPY25_004409"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCS0929847.1"
                     /translation="MKNINPTQTSAWQALQKHYDEMKDVTIAELFANDSDRFAKFSAT
                     FDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALR
                     NRSNTPIIVDGKDVMPEVNAVLEKMKTFSQAIISGQWKGYTGKAITDVVNIGIGGSDL
                     GPFMVTEALRPYKNHLTMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKSAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPILLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PAQLEHVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA"
     gene            2280..3629
                     /gene="lysC"
                     /locus_tag="OPY25_004410"
     CDS             2280..3629
                     /gene="lysC"
                     /locus_tag="OPY25_004410"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HCS0929848.1"
                     /translation="MTEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGMEPGERFATLDAIRKIQFDILDRLRHPNVIREEIERLLENITILAEAA
                     SLATSAALTDELVSHGELMSTLLFVEILRERDVQAHWFDVRKVMRTSDRFGRAEPDVA
                     ALAELAAQQLLPRLSETLVITQGFIGSESKGRTTTLGRGGSDYTAALLAEALHAARVD
                     IWTDVPGIYTTDPRVVPVAQRIDEIDFEEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPQAGGTLVCNKTQNPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNNLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGDDAEKVVQKLHQNLFE"
BASE COUNT          870 a         1002 c         1032 g          929 t
ORIGIN      
        1 atcagcatcc gtataatctg aaaataacgc agagtgattt tctggttatt gcttatttta
       61 ggattaagct caatataaaa ttgtggggat aaagacggac aagcggaatt atcttataaa
      121 aaaagccgat gtgaatatcg gcctttttat tatcttattc tctttttgcc ggatggcggc
      181 gaaacgcctt atccggccta cagacgctat gcattacgta gaccggataa gcgcagcgcc
      241 atcaggcgcg ccaggcttta taacggttaa tcagaccgtt agtagagcta tcatgggacg
      301 aaatagcttt atcatcgccc agctccggca gaatacggtt agccaactgt ttacccaact
      361 caacgcccca ctggtcgaaa gtaaagatgt tcaggatgac gccctgcgta aagattttat
      421 gctcatacaa cgcaatcagc gcgcccaggc tgaacggcgt aatttcgcgc agcagtatag
      481 agttggtcgg gcggttgcct tcaaacactt tgaatggcac aacgtgttca agctgcgccg
      541 gatctttacc ctgatcgcga tattcctgct caaccacctc gcgggattta ccaaacgcca
      601 gcgcttcggt ctgcgcgaag aagttagaca gcagcttctg atgatgatcg gatagcgggt
      661 tatgggtgat agccggggcg ataaagtcac acggcaccat tttagtaccc tggtgaatca
      721 attgataaaa cgcgtgctga ccgttggtgc ctggttcgcc ccagataatt gggcctgtct
      781 ggtaatccac ggcgttgccg ttacggtcaa cgtatttacc gttggattcc atgttgccct
      841 gctggaagta ggcggcgaaa cggtgcatat actggtcgta cggcagaatg gcttcggttt
      901 ccgcgccgaa gaaattgttg taccagatgc caatcaacgc cagcagaatg ggtaggtttt
      961 tctccgccgg agtggtggag aaatgcttgt ccatcgcgtg cgcgccggaa agcagctcga
     1021 caaagttgtc gaaaccgacg gacagaataa tggacagtcc gatggcagac cacagcgagt
     1081 aacgaccgcc gacccagtcc cagaactcga acatattggc cgtgtcgata ccaaattcgc
     1141 cgaccgcttt ggcgttggtg gagagcgcag caaagtgttt cgccacgtgt ttttcatcgc
     1201 ctgcactttt caggaaccag tcgcgcgcgc tgtgggcgtt ggtcatggtt tcctgcgtgg
     1261 tgaaggtttt cgacgccacc aggaacagag tcgtttccgg gttcactttt ttcagcactt
     1321 cagcgatgtg ggtaccatca acgttagaga cgaagtgcat agtcagatga tttttatacg
     1381 gacgcagcgc ttcggtcacc atgaacgggc cgaggtcgga accgccgata ccgatgttca
     1441 ccacgtcggt gatggcctta ccggtgtagc ctttccactg accggagata atcgcttgcg
     1501 agaaagtttt cattttctca agcacggcgt tcacttccgg catcacatct ttgccgtcca
     1561 caatgatcgg cgtattgcta cggttacgca gcgccacgtg cagcacggcg cggtcttcgg
     1621 tgcggttgat cttctcgccg gagaacatgg atttaatcgc gccggccaga tcggtctctt
     1681 tcgccagatc ctgtaatttt gccagcgtct cttcggtgat gcggtttttg gagaagtcca
     1741 ccagcatcag atcgtcaaac gtcgcggaaa atttagcgaa acggtcgcta tcgttcgcga
     1801 aaagctcagc gatcgtaacg tctttcattt cgtcgtagtg tttctggagc gcctgccagg
     1861 cagaagtctg cgttggattg atgtttttca ttagcaatac tcttctgatt tgagaattgt
     1921 gactgggatc gattgtaacg ccagtcacag aaaagtgtga ttgttttagt gccgttgccc
     1981 caggcactgt cgaatgagga taaaaagtat ataccctaaa taattcgagg tgcagaaagg
     2041 cggcaagtgg gtgagtcgcc gggcgcatag ataagccaac attcctacaa acgggtatcg
     2101 gggttataag cgctgttact gagcctaaac tcagcataaa aaatccgcat aatcccaacg
     2161 ttgacagtcc agtccacaac ttttatttat aaatacgtta cttgcatttg cgcctgcacc
     2221 ggtttctgtt ctgcctttgt gccatggtcg cgtttttcat ttcctgacac gaggttgata
     2281 tgacagagat cgttgtttcc aaatttggcg gtaccagcgt cgctgatttt gacgccatga
     2341 accgtagcgc ggatatcgta ctttccgacg ccaatgttcg tttagtcgtg ctttccgcgt
     2401 ctgccggcat cactaatctg ctggtggcgc tggccgaagg gatggagccc ggcgaacgtt
     2461 tcgctacgct cgacgccatc cgtaaaatcc agttcgatat ccttgatcgt ctgcgtcatc
     2521 cgaatgtcat tcgcgaagag attgaacgcc tgctggaaaa catcactatt ctggcggagg
     2581 cggcatcgct ggcgacatcg gcagccctga ccgatgaact ggtcagccac ggcgagctaa
     2641 tgtctaccct gctatttgtt gagatcctgc gtgaacgcga cgtacaggcc cactggttcg
     2701 acgtgcgcaa agtgatgcgt accagcgatc gctttggtcg tgcggaaccg gacgtcgcag
     2761 cgcttgcgga actggccgcg cagcagttgc tcccgcgcct gagcgaaacg ttggtcatta
     2821 ctcagggctt tatcggcagt gaaagcaaag gccgcaccac gacattaggc cgcggcggca
     2881 gcgactatac ggcagcgttg ctggctgaag cgctccacgc cgcgcgggtt gatatctgga
     2941 cagatgtgcc cggtatttac accaccgacc cgcgcgtagt gcccgtcgcg cagcgaattg
     3001 atgaaatcga ctttgaagaa gcggcggaga tggcaacctt cggcgcaaaa gtactgcatc
     3061 cagccacctt actcccggcc gtgcgcagcg atatcccggt cttcgttggc tccagtaaag
     3121 atccgcaagc gggcggtacg ctggtgtgca ataaaaccca aaacccgccg ctgttccgcg
     3181 cgctggcgct gcgccgcaat caaacgctat tgacgctgca cagcctgaat atgctgcact
     3241 cacgaggttt cctggcagag gtgttcggca ttctggcgcg gcataatatt tcggtagatc
     3301 tgattaccac ttcggaggtg agcgtcgcgc tgacgctgga tactaccggc tccacctcca
     3361 cgggcgatac gttactgacc caatccttat tgatggagct ttccgcgctg tgtcgggtcg
     3421 aagttgaaga aggactggcg ctggtcgcgc tgattggcaa caacctgtca aaagcctgcg
     3481 gtgttggtaa agaagtgttt ggcgtcctgg aaccgttcaa cattcgcatg atttgttacg
     3541 gcgcctccag ccacaatctg tgcttcctcg tgccgggaga cgatgccgag aaagtggtgc
     3601 aaaagctaca tcagaactta tttgaataat cgccctgaca cgacagcggg tgagcgctat
     3661 caggcaatac gctgccggat ggcgacgcaa gcgccttatc cggcggttcc cacgtcaggc
     3721 actgccggcg gaatactgct ccagaaagcc aattacagaa ggcaggaatc cgtacaccct
     3781 gctcgtccca tcaatatggg cagctttccc ctatttatgc cctcctcatt ttg
//
LOCUS       DAJVKX010000230         3728 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.230, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000230 DAJVKX010000000
VERSION     DAJVKX010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3728
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.230"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            239..551
                     /locus_tag="OPY25_004411"
                     /pseudo
     CDS             239..551
                     /locus_tag="OPY25_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558297.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(680..1708)
                     /locus_tag="OPY25_004412"
     CDS             complement(680..1708)
                     /locus_tag="OPY25_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HCS0929849.1"
                     /translation="MEDKYLTQSPAGEFIMFASGDGKVRVECRFESNTLWLSQGMICE
                     LYGKAKATISEHIKNIFADGELEENSVVRFYRTTASDGKNYQIQYFSLPLILAVGYRV
                     RSPRGTQFRQWATQTLQEYLIKGFVMDDERLKNPPVGSSAVPDYFDEMLERIRDIRAS
                     ERRVYLRVREIFALAADYQPSLKETTQFFQTIQNKLHFACTGYTAAELIHQRADACQP
                     HMGLTSYKGEEVRKCDVTVAKNYLTQDEVSELNRVVNMWLDFAEDQARRRQQVFLRDW
                     QDKLDQFLQFNDREVLQGAGKVSKKMADEKAQAEYSQFAEQQRRLKEAEGEKDIAALL
                     QWKTEPKK"
     gene            complement(1800..2630)
                     /locus_tag="OPY25_004413"
                     /pseudo
     CDS             complement(1800..2630)
                     /locus_tag="OPY25_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014227719.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            complement(2779..3375)
                     /locus_tag="OPY25_004414"
     CDS             complement(2779..3375)
                     /locus_tag="OPY25_004414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02646 family protein"
                     /protein_id="HCS0929850.1"
                     /translation="MTLLLNEQYHLCCYSEIRADLRGLGYHIEHVENKSQQPGRTFDY
                     QNLAASALDSENGLPQLGINTFGGHVQGKNKSVDMAQFIHCHLPDCSRYFAYLSNGHV
                     VPSIDLTEQEAEYAQYTIDHLNLNSGFLQTERRNHWEELEQLFEEHIEKDWDLHQLLQ
                     LDLVPSPDHKLHEFFSITRQFFQQEAEQVLQSHAPALI"
BASE COUNT          949 a          879 c          895 g         1005 t
ORIGIN      
        1 acaggacgta tgggagaaca agggtataaa gatgaaatgc ttgcagtatc taatagataa
       61 caatgaaaaa tcaggtaact gagaaactat tcagtgttta ggttgatgtg atattgagtc
      121 attcagccgc tacagcacat tatcaggata atttcgtctg gataaaacgg aggaatgaat
      181 cgccacaggt ttaacagaca ccgctgagtc atttaagatg acttaaagag agaagcccat
      241 gagcggtaaa cgttatccca aagcgtttaa aattaaagcg gtaaaacagg ttattgagcg
      301 cggccattct gtttccagcg tcgcaacacg tcttgatatt actacccata gtctttacgc
      361 ctggataaag ccgccacatt cacgacggca tcatgttgac ctgaatctga cggggcatac
      421 aggcagttct ggctggaatc gggctgtgtt tatggctatc gcaagatctg tctcgatctg
      481 cgggatatca ggaacaatgc ggtgtaagca aagtctggtg gttgatgcaa cgtgtgggga
      541 taaaggctcg ggcgatcaca ggaatcgtat ttgaatgtta acttattgat tttatgttta
      601 tattttgtat tggataaatg agtaaccccc ataagcaccc ccaaatgatt ttgcttgtgg
      661 ggtttgggga catcctgagc tactttttag gctctgtttt ccactgtaac aaagcggcga
      721 tatctttctc accttcggct tcttttaaac gccgttgttg ctcggcaaac tggctatatt
      781 ccgcctgcgc tttttcatcg gccattttct tactgacttt acctgcccct tgcaaaacct
      841 cacggtcgtt aaattgcagg aactgatcca gcttatcctg ccagtcgcgt aaaaagacct
      901 gttgacgacg acgggcctga tcttcggcga aatccagcca catgttaact acgcggttaa
      961 gctcgctgac ttcatcctga gtgagataat tttttgccac cgtcacgtca catttgcgca
     1021 cctcttcacc tttatagctg gtcagcccca tatgcggctg gcaggcgtca gcacgctgat
     1081 gaatgagttc agcggcggta tacccggtac aggcaaaatg taacttgttc tggatggttt
     1141 gaaaaaactg cgtggtttct ttgagggacg gttgataatc ggcggccaga gcaaagatct
     1201 cgcgtacccg caaataaacc cgacgttcgc tggcgcggat atcgcggata cgctccagca
     1261 tctcatcgaa atagtcgggt acagccgatg aacccacggg cggatttttc aggcgctcat
     1321 cgtccatcac aaaacctttg atcaggtatt cctggagcgt ctgggttgcc cactggcgga
     1381 actgcgtgcc gcgcggggag cgaacgcggt agccgacagc gagtatcaac ggcaaactaa
     1441 agtattgaat ctgataattt ttcccatcac tggcagttgt tcggtaaaac cgaacaactg
     1501 aattttcttc aagctcgcca tctgcaaaga tgttctttat atgctcactg atggtggctt
     1561 tagctttacc gtatagttcg cagatcattc cctgagagag ccacagtgta ttgctttcaa
     1621 agcggcattc aacacgcact ttcccgtcac cgctggcaaa cataatgaat tcacctgccg
     1681 gggattgggt taagtattta tcttccatgt cgcctccact tacatctgac tcgtgatgct
     1741 gtaatccgct tagtatgcca gaaattcctg gtgaagctca ttacgcagat agcgtttatt
     1801 ttggcgggta gcgcccccgg atagtgtttc atcacgatat cattcatctt ctccaccaga
     1861 tccagacgct taaacgtgat atgcccactg cctttctgaa agtagtgcat agagaataaa
     1921 tcatcctcaa aaacctgctg atgcgggtta tcacgaatga agtccatcag tcggatagtc
     1981 acatcgtgtc ggttatcggg aatggtttta ccatccagca ggaacaacat gcgctccaga
     2041 tccgcaatct ggtcacgccg tcagccccaa ttcaggctgt agccccatcg gtcgtgcttt
     2101 accaggccgt taacgatgat ccgcttaccg aagcagcagg gattattggt tttatagtcc
     2161 cagcttagcc ctttaaatac attgataatc ccacgttcga aaacatcctg tttattgtgg
     2221 tggagttgtt caaaggtgct caggatgttg gcttcgctga tggccggaag atctcctcct
     2281 tcgagatttt tagcccactg gctgcgggct tcagcgtcca ttaaggtcaa catcccggac
     2341 ttcagcatca gatcgcgcca aatgctgcgg tcaatattac gggtgatcac cggcatcgct
     2401 ttatcaaccg gttgcatcaa ccagcagtca aaggaatggc gctgtcgcat cgcccaatgc
     2461 tccgctacat caccaccgat gctggaggta agccgcgaga tgtcatcaag cttatgaatc
     2521 aggatttcta tcaggctcag cgcagcgtcg cgccctgtga cgatgcattc aatactggtc
     2581 gagcaaatta gctcattatg gtcagttaag acttcagctt ctgtttgcat atttttggtc
     2641 catataaaag caaacgcgcc tgccgggagt ggcaggcgca ttatgcggtg aaataaaggt
     2701 gaataaatat tgagggtgta aatcaggaag gcgactcgca ataaatcatg ctgtcgccct
     2761 gaatcaggaa tagtggtgtt aaattaatgc aggggcgtgg ctctgtaata cctgttcagc
     2821 ttcttgctgg aaaaactggc gtgtaatgct gaagaattca tgcagtttat gatctggcga
     2881 agggaccaga tcaagctgaa gtaattggtg cagatcccag tctttctcaa tatgttcttc
     2941 aaaaagctgt tccagctctt cccaatgatt acgacgctcc gtttgaagga atccgctgtt
     3001 caggttcagg tgatcaatgg tgtactgtgc gtactcagct tcctgctcag ttaaatctat
     3061 tgaaggaacc acatgcccat tagataaata ggcaaaataa cgagaacagt cagggaggtg
     3121 gcaatgaata aactgtgcca tatccacaga tttattcttt ccctgtacat gaccaccgaa
     3181 cgtgttgatg ccaagctggg gcaaaccatt ctcagagtct aacgcgctgg ctgcgagatt
     3241 ttgataatcg aaggttcgcc ctggctgctg gcttttattt tcgacgtgtt caatgtgata
     3301 gccgaggcca cgcaaatcag cacggatttc gctgtaacag caaagatgat attgctcatt
     3361 gagcagaagc gtcactaaat ctgctttgtc tcgtctaaag tttcgccagc gacgggtcga
     3421 ttgatccgaa tcttgtggtg gattttcatt tgcagtgagt aaggcatctg tccccggcga
     3481 gttttgatca catgcctcat tgtgccttcc ctttcagaaa gttacggcat cgacaaacgt
     3541 agcgcctgcg ttaataaacg taaggctata gtgccttcaa gtagatgagt aagctgcgac
     3601 gttactgctc gtatgaacac catccaccct tatgatgtga gcccgtaccc ccatgtggat
     3661 gttgaccctt tgggcaggca agcgcaccgg atgatgccgt gacggtaata aaagcgataa
     3721 tcatcgct
//
LOCUS       DAJVKX010000231         3681 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.231, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000231 DAJVKX010000000
VERSION     DAJVKX010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3681
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.231"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(113..835)
                     /gene="fimY"
                     /locus_tag="OPY25_004415"
     CDS             complement(113..835)
                     /gene="fimY"
                     /locus_tag="OPY25_004415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis regulator FimY"
                     /protein_id="HCS0929851.1"
                     /translation="MRSVPCRERHRRLRNAKDCACRYHSPTPQIFDRLELLNQQLNYA
                     LPVGIISQAIITTDNYLGYSLSHYLFSGKRTAAFRSLDDISLWIEKGSLRQLIVDMET
                     LPVSCIEALNQLHALSWQQSDIQIYLLVSDKTPAIAQFIRMAGRFFVLSRRQNLASVR
                     EALLSAAEPRLSESFSRTDWLMIETLAQGASLKEIARQQSVPYHRVVYRLKQLITLLN
                     LPHRQSFLRLIQQLNVTFHDIF"
     gene            complement(854..1165)
                     /locus_tag="OPY25_004416"
     CDS             complement(854..1165)
                     /locus_tag="OPY25_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCS0929852.1"
                     /translation="MVAQGTLLKERINPPHLASSPTRHSYLNSGLLKSEPIVHLSTAQ
                     LIGYEVLTQLPSEHDSEVFFQQLMLMEGIETSEQRGIAFYAGATMGQGYLWPAILPDI
                     Y"
     gene            complement(1327..1923)
                     /gene="fimW"
                     /locus_tag="OPY25_004417"
     CDS             complement(1327..1923)
                     /gene="fimW"
                     /locus_tag="OPY25_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimW"
                     /protein_id="HCS0929853.1"
                     /translation="MLSIAIKEQNSHFEHGLKIIMTRLANQWQQKIDFLPPEEIDNAD
                     IAFLTLDDDWFSAGCYQIPMHTQHQLRVIICNKCDKEKLMFRPCLYMLPHIYREDDVE
                     EITRKMILILHKRALRHSVPSGICHYCTTRHFSVTERHLLKLIASGYHLSETAALLSL
                     SEEQTKSLRRSIMRKLHVKTEQQFLKYIRVNLHFLLSK"
     gene            2178..2254
                     /locus_tag="OPY25_004418"
     tRNA            2178..2254
                     /locus_tag="OPY25_004418"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2212..2214,aa:Arg,seq:tct)
     gene            complement(2276..2398)
                     /locus_tag="OPY25_004419"
                     /pseudo
     CDS             complement(2276..2398)
                     /locus_tag="OPY25_004419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(2370..3037)
                     /locus_tag="OPY25_004420"
                     /pseudo
     CDS             complement(2370..3037)
                     /locus_tag="OPY25_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611920.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(3423..>3681)
                     /locus_tag="OPY25_004421"
     CDS             complement(3423..>3681)
                     /locus_tag="OPY25_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929854.1"
                     /translation="VIFEFNKNPADSLDENTAMFISLKTKDGKVINADVDKKTFQIDG
                     RWLSGRAINGIDSNELESITSGTWDVRTGARTNENITEIIK"
BASE COUNT          952 a          794 c          813 g         1122 t
ORIGIN      
        1 gtcgcttacc aggacgagtt gtaaatatta attttatgtg aaatatttac atttaatggc
       61 agtgaaaata agtaatttct taaaaaatct tattcaccaa aacgttactt cgttaaaaaa
      121 tgtcgtggaa agtaacgttt agctgctgga tcagccgaag aaagctttgc ctgtggggaa
      181 ggttaaggag ggtgataagt tgtttaagcc ggtaaaccac acgatgataa ggtacgcttt
      241 gctgacgtgc tatttctttt aaagaggcac cttgcgctaa agtttcaatc atcaaccagt
      301 cagtacggct aaagctttcc gataagcgag gttcggcggc tgataacaag gcttcgcgta
      361 cagaggccag attttgtcgt cgcgacagga caaaaaaacg cccagccata cggataaact
      421 gagctatagc gggggtttta tctgatacca gcaggtaaat ctggatatcg ctttgttgcc
      481 aactgagcgc gtgtagctgg ttaagcgcct caatacagga gacaggtagc gtctccatat
      541 ctacaatcag ttgtctgagc gacccctttt caatccacaa agaaatgtca tctaatgagc
      601 ggaatgctgc ggtacgtttt ccggaaaata agtagtgact caatgaatag ccgaggtagt
      661 tatcagttgt aattattgcc tgagaaatga taccaaccgg caaggcataa tttagctgtt
      721 ggttcagtaa ctcaaggcga tcaaatatct gcggcgttgg agagtgataa cggcaggcgc
      781 agtctttggc atttcttaaa cggcggtgtc tttccctgca tggtacgctg cgcatcctgc
      841 tttttccatt gctctaatat atatctggta atatggctgg ccataaataa ccttgtccca
      901 tcgttgcacc agcgtaaaaa gcaatgcctc gttgctctga tgtttcaatg ccttccatca
      961 gcattaactg ctgaaaaaaa acttcgctat catgttctga cggaagttgc gtcaggacct
     1021 catagccgat taattgcgca gttgagagat gaacgattgg ctcagatttt aacaatccgc
     1081 tgttgagata tgaatggcgt gttggcgaag acgccaggtg tgggggattt atcctttcct
     1141 ttaataaagt accctgtgcc accaaacact ccttcaggca tttatgatgc agccatatat
     1201 ttttgacccc tgaatctatc aggatattat gggtatcatt gtggcagcgt taaaaaaatg
     1261 cctgtaggta tcgttactta attattggtg agatatttcg taagctttgt aaaaagttaa
     1321 gtgagtttac ttactgagta agaaatgaag gttaactcta atatatttta aaaactgctg
     1381 ctccgtttta acatgtaatt ttcgcataat gctccggcgg agtgactttg tctgctcttc
     1441 agaaagtgaa agtaaagcgg ccgtttcgct taaatgataa ccgctggcga tcagttttaa
     1501 taagtgacgt tctgttactg aaaaatggcg agtcgtgcag tagtggcaga tgccagaagg
     1561 gacgctatgt cgaagcgctc gcttatgtaa gatcaatatc attttccggg taatttcttc
     1621 aacatcatct tcccgataaa tatgcggcag catatacaga catggtctga acatgagctt
     1681 ttctttatcg catttattac aaataattac ccgtagctga tgttgagtat gcataggtat
     1741 ctggtaacag cctgcgctga accaatcatc atccagggtc aggaaagcga tatcggcatt
     1801 atctatctct tctggcggca gaaagtcaat tttctgctgc cattgattcg ccagacgcgt
     1861 catgatgatt ttcaaaccat gctcaaagtg actgttttgt tccttaatag cgatactcag
     1921 cataaaaaat atcctacacg gcaggtgagt catggtgaaa tattaaagaa actgattgat
     1981 tatctaaata ctggcggctt taattcccac tttatgcgtg ctgagatgtg tccaggcgat
     2041 ttcctggaac ctggcattgc gccagaaaag acgatattcg tacacttagt cagcaaccag
     2101 aacaaaagcc attgactcag gagtgcctga ccgtataatt ctcgcgtttc gtctacatga
     2161 agtcttcact tcacaaggcg cccttagctc agttggatag agcaacggcc ttctaagccg
     2221 tgggtcgcag gttcgaatcc tgcagggcgc gccacttata aatcaacgcg ttacgcttct
     2281 ttatttcctc cttattttcc atatgggaca tatttgggac atcatcacca aaaatgtcgt
     2341 ctattttcct cgcgtgttcc gttaaatgat taggcgcaag gtgagcatat ctgtgaatcg
     2401 ccacggataa cctggacact tctgagtcgt tgatgatata ggttttcata ttcagccggt
     2461 ggcatctgct cgctcgaacc atgccgacgt ctactgttat aaaacatttc tatgtaatta
     2521 aaaatatcgc ttctggcttc gtctctcgtt ccgtagatct ttttctttat ccgttcacgc
     2581 ttcagtagct ggaaaaagct ttctgcaacc gcattttcat gacagttgcc acgacggctc
     2641 atactgccct ccagtccgtg cgatttcagg atcgactgcc attcatagcg ggtgattatg
     2701 tcgccacacg gccatcagga gcgcattcag gactccatct tttgtcattc atggttgcag
     2761 tgaccaattg agtctactgc ggcttttttt aatatgtccc gttcgtcagt aacccgcttc
     2821 aactctttcg ggagtcggcg gattccggtc tgatcatctg actgctcttt atttctttat
     2881 tggtggagga gttcgacccg tacttcttta tcctggcgta aagactgtgg gtagtaatat
     2941 cgagatgtgt tgcgacgctg gaaacagaat ggccgcgctc aacaacctgt cttaccgctt
     3001 caattttaaa ctcttcggga taacgtttac cgctcatagg cacctctctt taagtcatct
     3061 taaatggatc tgaggtgtct gttaaacctg tggtgattca cattgaccgc agattatcag
     3121 attcctttac ccggtagtga aaccagtagg ggtcagttta tccgcactaa aagacggtgt
     3181 tcctgcatct gtggtggagt tgaaccggat gggctttggg cacatgcgta tcctgcgtgt
     3241 attggtcagt tgccggagtc tggattaatg cactatggct ccgttgggtt cttttttggg
     3301 actgatggcg cattgcgact tcttgctaag aaacctgatg gggcatttgt gacatacgat
     3361 atgtaggaat ccccgccgcc cgttacccat tggtggcggg gaacattaat tatacatgaa
     3421 tgttatttaa ttatttccgt aatattctca tttgtcctcg cccctgttct aacgtcccat
     3481 gtcccagatg taattgattc taattcattt gaatctatgc cgttaatcgc ccgtcctgaa
     3541 agccatcttc cgtctatttg aaatgtcttc ttgtcgacat ctgcatttat aacttttcca
     3601 tcctttgttt ttaagctaat gaacatcgct gtattctcat caagagaatc agcaggattc
     3661 ttattaaact caaatattac a
//
LOCUS       DAJVKX010000232         3674 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.232, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000232 DAJVKX010000000
VERSION     DAJVKX010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3674
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.232"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            4..948
                     /gene="rfbN"
                     /locus_tag="OPY25_004422"
     CDS             4..948
                     /gene="rfbN"
                     /locus_tag="OPY25_004422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O antigen biosynthesis rhamnosyltransferase
                     RfbN"
                     /protein_id="HCS0929855.1"
                     /translation="MKITLIIPTYNAGSLWPNVLDAIKQQTIYPDKLIVIDSGSKDET
                     VLLASDLKNISIFNIDSKDFNHGGTRNLAVTKTLDADVIIFLTQDAILADSDAIKNLV
                     YYFSDPLIAAVCGRQLPHKDANPLAVHARNFNYSSKSIVKSKADIEKFGIKTVFMSNS
                     FAAYRRSVFEELSGFPEHTILAEDMFMAAKMIQAGYKVAYCAEAVVRHSHNYTPREEF
                     QRYFDTGVFHACSPWIQRDFGGAGGEGFRFVKSEIQFLLKNAPFWIPRALLTTFAKFL
                     GYKLGKHWQSLPLSTCRYFSMYKSYWNNIQYSSSKEIK"
     gene            949..2388
                     /locus_tag="OPY25_004423"
     CDS             949..2388
                     /locus_tag="OPY25_004423"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HCS0929856.1"
                     /translation="MSFLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKR
                     LASLSTEEPVVICNDRHRFLVAEQLREIDKLANNIILEPVGRNTAPAIALAAFCALQN
                     ADNADPLLLVLAADHVIQDEIAFTKAVRHAEEYAANGKLVTFGIVPTHAETGYGYIRR
                     GELIGNDAYAVAEFVEKPDIDTASDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIY
                     KACEKAVGHINPDLDFIRIDKEEFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSW
                     SSLWDISNKDHQRNVLKGDIFAHACNDNYIYSEDMFISAIGVSNLVIVQTTDALLVAN
                     KDTVQDVKKIVDYLKRNDRNEYKQHQEVFRSWGKYNVIDSGKNYLVRCITVKPGEKFV
                     AQMHHHRAEHWIVLSGTARVTKGEQIYMVSENESTFIPPDTIHALENPGMIPLQLIEI
                     QSGTYLGEDDIIRLEQRSGFSKEWTNERS"
     gene            2375..>3674
                     /gene="rfbK"
                     /locus_tag="OPY25_004424"
     CDS             2375..>3674
                     /gene="rfbK"
                     /locus_tag="OPY25_004424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen biosynthesis phosphomannomutase RfbK"
                     /protein_id="HCS0929857.1"
                     /translation="MNVVNNSRDVIHSSGIVFGTSGARGLVKDFTPQVCAAFTVSFVA
                     VMQEHFSFDTVALAIDNRPSSYGMAQACAAALADKGVNCIFYGVVPTPALAFQSMSDN
                     MPAIMVTGSHIPFERNGLKFYRPDGEITKHDEAAILSVEDTCSHLELKELIVSEMAAV
                     NYISRYTSLFSTPFLKNKRIGIYEHSSAGRDLYKPLFIALGAEVISLGRSDNFVPIDT
                     EAVSKEDREKARSWAKEFDLDAIFSTDGDGDRPLIADEAGQWLRGDILGLLCSLALGA
                     EAVAIPVSCNSIISSGRFFKHVKLTKIGSPYVIEAFNELSRSYSRIVGFEANGGFLLG
                     SDICINEQNLHALPTRDAVLPAIMLLYKSRNISISALVNELPTRYTHSDRLQGITTDK
                     SQSLISMGRENLSNLLSYIGLENEGAISTDMTDGMRITLRD"
BASE COUNT         1060 a          649 c          812 g         1153 t
ORIGIN      
        1 taaatgaaaa taacattaat tattcccaca tataatgcag ggtcactttg gcctaatgtt
       61 ctggatgcga ttaagcagca aactatatat ccggataaat tgatcgttat agactcaggt
      121 tctaaagatg aaacggttct gttagcctca gacctgaaaa atatatcaat atttaatatt
      181 gactctaaag attttaatca tggaggaacc agaaacttag cagttacaaa aactctggac
      241 gctgatgtta taatttttct aacacaagat gcaattctcg cggattcgga tgcaattaaa
      301 aatttggttt attatttttc agatccattg atagcagcgg tttgtggtag acaacttcct
      361 cataaagatg ctaatcccct tgcagtgcat gctaggaatt ttaattatag ctcaaaatct
      421 attgttaaaa gcaaggcaga tatagaaaaa tttggtatta aaactgtatt tatgtccaat
      481 tcttttgctg cctatcgccg ttccgttttt gaagagttaa gtgggtttcc tgaacataca
      541 attcttgccg aggatatgtt tatggcggct aagatgattc aggcgggtta taaggtcgcc
      601 tactgcgctg aagcggtggt aaggcactcc cataattata ccccgcgaga agagtttcaa
      661 cgatattttg atactggtgt atttcatgct tgttctccgt ggattcagcg tgactttggc
      721 ggagccggag gagagggttt ccgattcgta aaatcagaga ttcaattcct gcttaaaaat
      781 gcaccgttct ggattccaag agctttatta acgacctttg ctaaattctt gggttacaaa
      841 ttaggcaagc attggcaatc tttaccgttg tctacatgtc gctattttag catgtacaag
      901 agttattgga ataatatcca atattcttcg tcaaaagaga taaaataaat gtcttttctt
      961 cccgtaatta tggctggcgg cacaggtagc cgtttatggc cgctttcacg cgaatatcat
     1021 ccgaagcagt ttttaagcgt tgaaggtaaa ctatcaatgc tgcaaaatac tataaagcga
     1081 ttagcttcac tttctacaga agaacccgtt gtcatttgca atgacagaca ccgtttctta
     1141 gtcgctgaac aactccgtga aattgacaag ttagcaaata atattattct cgaaccagta
     1201 ggccgtaata ctgcaccagc gatcgctctt gccgcgtttt gtgcgctcca gaatgctgat
     1261 aatgctgatc ctcttttgtt ggttcttgct gcagatcatg tgatccagga tgaaatagcg
     1321 tttacgaaag ctgtcagaca tgctgaagaa tacgccgcaa atggtaagct tgtaactttt
     1381 ggtattgttc caacgcatgc tgaaacgggt tatggatata ttcgtcgtgg tgagttgata
     1441 ggaaatgacg cttatgcagt ggctgaattt gtggagaaac cggatatcga taccgccagt
     1501 gactatttca aatcagggaa atattactgg aatagcggta tgtttttatt tcgtgcaagc
     1561 tcttatttaa acgaattgaa gtacttatca cctgaaattt acaaagcttg tgaaaaggcg
     1621 gtaggacata taaatcccga tcttgatttt attcgtattg ataaagaaga gtttatgtca
     1681 tgcccgagtg attctatcga ttatgcagtt atggagcaca cacagcatgc cgtggtgata
     1741 ccaatgagtg ctggctggtc ggatgtggga tcctggtcct cactttggga tatatcgaat
     1801 aaagatcatc agagaaatgt tttaaaagga gatatcttcg cacatgcttg taatgataat
     1861 tacatttatt ccgaagatat gtttataagt gcgattggtg taagcaatct tgtcattgtt
     1921 caaacaacag acgctttact ggtggctaat aaagatacag tacaagatgt taaaaaaatt
     1981 gtcgattatt taaaacgaaa tgataggaac gaatataaac aacatcaaga agttttccgc
     2041 tcttggggaa aatataatgt gattgatagc ggcaaaaatt acctcgtccg atgtatcact
     2101 gttaagccgg gtgagaaatt tgtggcgcag atgcatcacc accgggctga gcattggata
     2161 gtattatccg ggactgctcg tgttacaaag ggagagcaga tttatatggt ttctgaaaat
     2221 gaatcaacat ttattcctcc ggatactatt cacgcgctgg aaaatcccgg aatgatcccc
     2281 ctgcagttaa ttgagattca atcaggtacc tatcttggtg aggatgatat tattcgttta
     2341 gaacaacgtt ctggattttc gaaggagtgg actaatgaac gtagttaata atagccgtga
     2401 tgttattcat tcatcaggta ttgtgtttgg aacgagtggg gctcgcggtc ttgtaaaaga
     2461 ttttacacct caggtatgtg ctgcttttac ggtttcattt gttgccgtta tgcaggaaca
     2521 tttttccttt gataccgtag cattggcaat agataatcgt ccaagtagtt atgggatggc
     2581 tcaggcgtgt gctgctgcat tggcagataa aggcgttaac tgtatttttt atggtgtggt
     2641 accaaccccg gctttggcct ttcagtctat gtctgacaat atgcctgcga taatggttac
     2701 gggaagtcat attccattcg agcggaacgg cctcaagttt tatcgtcctg atggtgaaat
     2761 cacgaaacat gatgaggctg cgatccttag tgttgaagat acgtgcagcc atttagagct
     2821 taaagaactc atagtttcag aaatggctgc tgttaattat atatctcgtt atacatcttt
     2881 attttctact ccattcctga aaaataagcg tattggtatt tacgaacatt caagcgctgg
     2941 gcgtgatctt tataagcctt tatttattgc attgggggct gaagtcatta gcttgggtag
     3001 aagcgataac tttgtaccta tagatacaga ggctgtaagc aaagaggatc gggaaaaagc
     3061 acgctcatgg gctaaagagt tcgatttaga tgccatattc tcaacagatg gggatggtga
     3121 tcgtcctctt attgctgatg aggccggtca gtggttaaga ggcgatatat taggtctatt
     3181 atgttcactt gcattggggg cagaagcggt cgctattcct gttagttgta atagcataat
     3241 ttcttctggc cgctttttta aacatgttaa acttacgaaa attggctcgc cttatgttat
     3301 cgaagctttt aatgaattat ctcggagtta tagtcgtatt gtcggttttg aagccaatgg
     3361 cggtttttta ttaggaagcg atatctgtat taacgagcag aatcttcatg ccttaccaac
     3421 tcgtgatgct gtattaccag caataatgct actttacaaa agtaggaata tcagcattag
     3481 cgctttagtc aatgaactcc caactcgtta cacccattct gacagattac agggaattac
     3541 gactgataaa agtcaatcct taattagtat gggcagagaa aatctgagca acctcttaag
     3601 ctatattggt ttggagaatg aaggtgcaat ttctacagat atgacagatg gtatgcgaat
     3661 taccttacgt gatg
//
LOCUS       DAJVKX010000233         3669 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.233, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000233 DAJVKX010000000
VERSION     DAJVKX010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3669
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.233"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            15..1994
                     /locus_tag="OPY25_004425"
     CDS             15..1994
                     /locus_tag="OPY25_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCS0929858.1"
                     /translation="MRLKSIVKSFALAGLLSSTALTPLFAQEAPKGATASTKQANNAL
                     YNQLPFSDNTDFTNAHKGFIADLPAEVIKGEQGNVIWNPQQYAFIKEGEKSPDTVNPS
                     LWRQSQLINISGLFEVTDGVYQIRNLDLSNMTIIEGKEGITVVDPLVSAETAKAGMDL
                     YFKNRGNKPVVAIIYTHSHVDHYGGVRGVVDEADVKSGKVKVYAPAGFMEAAVAENIM
                     AGNVMSRRASYMYGNLLKPDASGQVGAGLGTTTSAGTVTLIAPTNIIDKDGQKEVIDG
                     LTYDFMLAPGSEAPSEMLWFIEEKKLIEAAEDVTHTLHNTYSLRGAKIREPLPWSKYI
                     NEAIVRWGDKAEIIMAQHHWPTWGNENVVGLLKSQRDLYRYINDQTLRMANEGLTRDE
                     IAANFKLPDSLAKTWANRGYYGSISHDVKATYVLYLGWFDGNPATLDELPPEEAAKKF
                     VEYMGGADAILQKAKADFDQGNYRWVAQVVSKVVFADPNNQNARNLEADALEQLGYQA
                     ESGPWRNFYLTGAQELRNGVVKGPTPNTASPDTVRAMTPEMFFDFLAVHINGEKAGNA
                     RAVFNIDLGSDGGKYKLELENGVLNHTANAEAKDADATITLNRDTLNKIILKEETLKQ
                     AQDKGEVNVTGNAAKLDEMLGYMDKFEFWFNIVTP"
     gene            complement(2403..3017)
                     /locus_tag="OPY25_004426"
     CDS             complement(2403..3017)
                     /locus_tag="OPY25_004426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein B"
                     /protein_id="HCS0929859.1"
                     /translation="MKTHHHPTTFVHLINQIGLLGICVALVVAFYYQLVRHELPCPIC
                     LLQRAGLIIAGFGFLFNLCFGLRGIHYGMVIIGSILTGVMASRQICLHIMPGDTGYGS
                     AFFGLHFYTWTLITSILIIIAVAVVLAISSMNAAFRSLNINPNLFSIVGWVFLLLITA
                     NLISTVLECGGGECAANPVTYKLLSKQDIAFLKTGLLTRTVLRL"
     gene            complement(3027..3185)
                     /locus_tag="OPY25_004427"
     CDS             complement(3027..3185)
                     /locus_tag="OPY25_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929860.1"
                     /translation="MFMFLPFLLALSVAMGAINRKDKVSYILWAVLLIVTILSFIHHM
                     TNSLTLSF"
     gene            complement(3318..>3669)
                     /locus_tag="OPY25_004428"
     CDS             complement(3318..>3669)
                     /locus_tag="OPY25_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0929861.1"
                     /translation="LAGLILSATGWFFERPQVSTFSVHSILATLYLGAFAGVFGILCY
                     FALQQKANAFQASLVFLIFPLIAVSLEDYIYGYAISTHSMLLIIPLAIGIFLTLVARN
                     IPVTSRCRDNSSQK"
BASE COUNT         1063 a          807 c          868 g          931 t
ORIGIN      
        1 catgaggggt acaaatgaga cttaagtcga tcgttaaaag ttttgcgctg gcggggctac
       61 tctcttccac tgcgctgaca cctttatttg cccaggaagc cccaaaaggt gccactgctt
      121 caaccaagca agctaacaat gcgctttata accaacttcc tttctctgat aacaccgatt
      181 tcacgaatgc ccataaaggc tttattgctg atttacctgc agaggtgatt aagggagagc
      241 aagggaatgt catctggaat ccacagcagt acgctttcat aaaagaaggg gaaaaatctc
      301 ctgacactgt taaccctagt ctgtggcgtc agtcccaact aatcaatatc agtggcttgt
      361 ttgaagtaac agacggcgtc taccagattc gtaaccttga tttatccaac atgacgatta
      421 tcgaaggtaa agaggggatt acggttgtcg atccgctggt ttctgcggaa acagccaaag
      481 ccggtatgga tttgtatttc aaaaaccgtg gcaataagcc tgttgtcgcc atcatttata
      541 ctcatagcca tgttgaccac tatggtggtg tgcgtggcgt tgtcgatgaa gcggacgtga
      601 aatccggcaa ggtgaaagtg tatgcgcctg ctggctttat ggaggcagca gtagccgaga
      661 atattatggc cggcaacgtg atgagccgcc gtgccagcta tatgtatggc aacctcctga
      721 aaccagatgc ctccggccag gttggcgccg gactggggac gaccacctct gcggggacgg
      781 tgacactgat tgcgcccact aatatcattg ataaagacgg ccagaaagaa gtgattgatg
      841 gcctgactta cgactttatg ctggcccctg gttcggaagc cccttcggaa atgctgtggt
      901 tcatcgaaga gaagaaactc atcgaagccg cagaggacgt cactcacacc ctgcataaca
      961 cttactcgct acgcggcgca aaaattcgtg agccgttgcc gtggtcgaaa tatatcaacg
     1021 aagctatagt gcgttggggt gacaaagctg aaattattat ggcccagcac cactggccga
     1081 cttggggtaa cgagaatgtt gttggtctgc tgaaaagcca gcgagacctg tatcgttata
     1141 tcaatgacca gactctgcgt atggccaatg aaggtctgac tcgcgacgaa atagcggcca
     1201 acttcaaact accggatagc ctggcaaaaa cctgggccaa ccgcggctat tacggctcca
     1261 tcagccatga cgtaaaagca acgtatgtgc tgtatctcgg ttggttcgat ggcaatccgg
     1321 caacccttga tgagctgcca cccgaagaag cggctaagaa atttgttgaa tatatgggcg
     1381 gtgccgatgc gattcttcag aaagccaaag cagactttga ccaggggaac taccgttggg
     1441 ttgctcaggt ggtgagtaag gtcgtgtttg ccgatccaaa taaccagaat gcacgtaacc
     1501 ttgaagccga tgcgttggaa caattggggt atcaggctga atctggtcca tggcgtaact
     1561 tctacctgac cggtgcgcag gagctgcgta acggtgtggt taaaggtccg acgccaaata
     1621 cagcaagtcc ggataccgtt cgggcaatga cccctgaaat gttcttcgat ttcctggctg
     1681 tacatatcaa cggtgaaaaa gcgggtaatg cccgggcggt gtttaatatt gaccttggca
     1741 gcgacggcgg aaagtacaag cttgagctgg aaaatggcgt gctgaaccac acggctaatg
     1801 ctgaagcgaa agacgctgat gccacgatta ctctgaaccg tgacacgctg aataaaatta
     1861 tcctgaagga agaaactctg aagcaggctc aagataaagg agaagtcaac gttaccggta
     1921 atgctgcgaa actggatgag atgctgggct atatggacaa gtttgagttc tggttcaata
     1981 tagttacacc ataaatagat tccctgcggc gtcaatgctg cagggaagtt acttcagaca
     2041 attctgtacg tttttcatac tcgatttttc cttcattctt tatatcttgc ttcattttat
     2101 gtatttgctg ctgaagcaca tgaccctgat gccagtcagt cctgattctg ttatgcacag
     2161 cctttttcat cagatgacag taactggttg ttgcgtgatt caatggtctg cgagtctggt
     2221 caacatgctt ttagttagtt aaatgtgatt ctactaattc gtaatgcgaa ggttataagt
     2281 ttgattccta ttattgcacc atttcaacgt tactgaaact tccgtgttag cccataacca
     2341 ttccagtttc tacaagacag gtgcttgcta tatatttacc aatcagtcat tttaaaagtg
     2401 cgtcataacc ggagaactgt cctcgtcagg aggcctgttt tcagaaaggc aatatcctgc
     2461 ttcgacagta gcttatatgt gaccgggtta gcagcacatt cccctccgcc acattccagt
     2521 acagttgaaa taaggttggc agtaatcagt aatagaaata cccaaccgac aatactgaac
     2581 aggttcggat taatattcaa tgaacgaaat gcagcattca tgctactgat tgccagaact
     2641 accgcaacag caataataat gagaattgac gtaatcagag tccaggtata aaagtgtaat
     2701 ccaaaaaatg cagaaccata tcctgtgtca ccgggcatga tatgcaaaca tatttgccgg
     2761 gatgccataa ctccggtcag gatactgcca ataattacca tcccgtaatg tatgcctcgt
     2821 agaccaaagc agaggttaaa taaaaagcca aaaccggcga tgatgaggcc agcccgctgt
     2881 aataagcaaa ttggacaagg cagctcatgc ctaacgagtt gataataaaa ggctacaacc
     2941 agagcaacgc atatcccaag gagtcctatc tgattaatca gatgaacaaa tgttgttgga
     3001 tgatgatgcg ttttcataca cactccttaa aatgacaaag ttagcgaatt ggtcatatga
     3061 tggatgaatg ataaaatagt gacgatgagt aaaacggccc atagaatgta gctgacttta
     3121 tcctttctgt ttatggctcc cattgccacg ctcagtgcaa gcaagaatgg cagaaacatg
     3181 aacataaaaa actcctttat tacattgctt gttaatataa tcgctgtgta ttaccgggtc
     3241 tgtattccag cttatccacc ccgcattagc tggagctcag taaggcatca ggaattattt
     3301 gcgttattat aaatcgatta tttctgtgat gaattatccc gacatctgct ggttacaggg
     3361 atatttctgg cgacaagagt aagaaatatc ccgatagcta atggtataat aagcagcatt
     3421 gagtgtgttg aaatagcata tccataaata tagtcttcca gacttaccgc aatcagcgga
     3481 aagataagaa atacaagcga agcctggaag gcgttagcct tttgctgaag cgcaaagtag
     3541 cacaggatac caaaaactcc ggcaaaagcc ccgagataca gggtagctaa tattgagtgt
     3601 actgagaagg ttgatacttg tggtctttca aaaaaccatc ctgtcgcaga aagtatcaac
     3661 ccagctaaa
//
LOCUS       DAJVKX010000234         3602 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.234, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000234 DAJVKX010000000
VERSION     DAJVKX010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3602
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.234"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..900)
                     /gene="ilvE"
                     /locus_tag="OPY25_004429"
     CDS             complement(<1..900)
                     /gene="ilvE"
                     /locus_tag="OPY25_004429"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HCS0929862.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLRDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLVF
                     VGDVGMGVNPPPGYTTDVIIAAFPWGAYLGAEALDQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDK"
     gene            complement(918..1181)
                     /gene="ilvM"
                     /locus_tag="OPY25_004430"
     CDS             complement(918..1181)
                     /gene="ilvM"
                     /locus_tag="OPY25_004430"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HCS0929863.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFQVCSMNMEAATDAQN
                     INIELTVASPRSVDLLFSQLSKLVDVAHVAICQSAATSQQIRA"
     gene            complement(1178..2824)
                     /locus_tag="OPY25_004431"
     CDS             complement(1178..2824)
                     /locus_tag="OPY25_004431"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HCS0929864.1"
                     /translation="MNGAQWVVHALRAQGVKTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARSTGKTGVCIATSGPGATNLITGLADALLDSVPVVAITGQVSAP
                     FIGTDAFQEVDVLGLSLACTKHSFLVQSLAELPRIMAEAFEVANAGRPGPVLVDIPKD
                     IQLASGELEPWFTTVDNEATFPQADVEQARQMLEQAKKPMLYVGGGVGMAKAVPALRK
                     FIAVTQMPVTCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPNASVIHMDIDPAEMNKLRQAHVALQGDLNSLLPALQQPLKIDAWRQSC
                     AELRAEHAWRYDHPGETIYAPLLLKQLSERKPADSVVTTDVGQHQMWSAQHMTYTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVICISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITRKDQVEAAL
                     DTMLASEGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(2827..2877)
                     /locus_tag="OPY25_004432"
     CDS             complement(2827..2877)
                     /locus_tag="OPY25_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929865.1"
                     /translation="MNNSIKFCFSRFTTGM"
     gene            complement(2964..3062)
                     /gene="ilvL"
                     /locus_tag="OPY25_004433"
     CDS             complement(2964..3062)
                     /gene="ilvL"
                     /locus_tag="OPY25_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HCS0929866.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            3414..>3602
                     /locus_tag="OPY25_004434"
     CDS             3414..>3602
                     /locus_tag="OPY25_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium chelatase"
                     /protein_id="HCS0929867.1"
                     /translation="MSLAIVHTRAALGVNAPPITIEVHISNGLPGLTMVGLPETTVKE
                     VRDRVRSAIINSGYEFPAK"
BASE COUNT          847 a         1010 c          881 g          864 t
ORIGIN      
        1 tttatcctcg gtttctccag tgaagagacc aaagaaggct tgttggatac gcttggtaac
       61 agggccgcaa cggccttcgc ctacctggat accatcaacg ctgcgtaccg gagtaatttc
      121 tgccgcagtt ccggacataa acacttcgtc ggccagatac agcgattcac gggacagcac
      181 ctgctcacgc acttcaatac ccagctcttt cgccagtttg atgatcgcgt cgcgagtaat
      241 gcctggcagc gcggaagagg taaacggcgg agtaaacagc acgccatctt ttacctcaaa
      301 caggttttcg cctgcgcctt cggatatata gccgtttaca tccagggcga tgccttcctg
      361 atagccgtgg cggcgcgctt cgctacccac cagcagtgag gaaagatagt tcccgcccgc
      421 tttggcggcg gtcggaatgg tgttcggcgc agcgcggttc caggaagaaa ccatcgcatc
      481 gatcccctga tccagcgctt cggcgcccag gtatgccccc cacgggaacg cggcgatgat
      541 gacgtcagtg gtgtatcccg ggggcgggtt aacgcccata ccgacatcgc ctacaaatac
      601 caacggacgg atataggcgc tggtcagatt atttttacga attacgtcgc ggcaggcttc
      661 catcagctca tcaatgctct gggaaaccgg aaaacgataa atttttgctg agtcgcgcag
      721 gcgctgcata tgttcacgat gacgaaacac taccgggcct ttgtgagagt cgtagcaccg
      781 aatcccttca aataccgacg taccgtagtg cagcgcgtga gacattacgt gaaccttcgc
      841 gtcttcccag cgcaccatct cgccattgaa ccaaatgtaa tcagcttttt tcgtcgtcat
      901 ttttcttcct tttgcgctca ggcgcggatt tgttgtgatg tggcagcgct ctggcagatt
      961 gcgacatgcg caacatctac cagtttactt aactgactaa acagtaagtc gaccgaccgg
     1021 ggactggcaa cggtcaattc aatatttata ttctgcgcat cggtcgcggc ttccatattc
     1081 atggagcaca cctgaaaacc acgatggcgc accacgcgta aaacacgttc taaggtttct
     1141 ggattaaagc gtgccgatac attgacctga tgttgcatca tgataatttc tccagcattt
     1201 cagagttact ggcgccaggc ggcaccaacg gccagacatt ttcaagttcg tcgattgaga
     1261 cgtgaagcag gtacggccct tcgcttgcca acatcgtgtc gagtgccgct tcaacctggt
     1321 ctttacgagt aatgtgctgg cctggaatgc cgaaggcgct ggccagcatg aggaaatcgg
     1381 ggttatcggt cagggtggtt tcgctatatc gctcctggaa aaacagttgc tgccattgtc
     1441 gaaccatccc taaccgctgg ttgtcgagta agactatctt caacggtaac tgcttgcgtt
     1501 ttacggtgcc caactcctga acattcatca tgaaggagcc gtcaccggag atacagataa
     1561 cggtatcatt cggtcgcgct acctgcgcgc caacggccgc cggtaagccg aatcccatcg
     1621 tccccagacc gctggaagtg atgaagttct ccgggcgggt gtaagtcata tgctgggctg
     1681 accacatctg atgctgcccc acatccgtcg tcaccacact gtctgcgggt ttgcgttccg
     1741 acaattgctt caacaacaac ggcgcataga tagtctcgcc aggatggtca tagcgccagg
     1801 cgtgttctgc gcgcagctct gcacaagact gacgccatgc gtcgatcttc agcggttgct
     1861 gtaatgccgg caacagcgaa tttaaatcgc cctgcaacgc gacgtgtgcc tgacgcagtt
     1921 tgttcatttc cgccgggtcg atatccatat ggattacgct ggcgttaggc gcaaacgtat
     1981 tcagcttacc ggtcacccgg tcatcaaaac gtgcacccac tgcgatcagt aaatcacact
     2041 cttgcaccgc gaaattagcc gctttagtac cgtgcattcc cagcatgccc agatagtacg
     2101 gataatcagc ttcaacagcc cccagacctt tcagcgtgca ggtaactggc atttgcgtta
     2161 ccgcgataaa tttacgcagc gccggaaccg ccttcgccat accaacacca ccgccgacgt
     2221 acagcatggg ttttttcgcc tgttccagca tctggcgcgc ctgttccaca tcagcctgcg
     2281 ggaaagtcgc ttcgttatcg acggtagtaa accagggttc tagctcaccg ctggccaact
     2341 ggatatcttt cgggatatcc accagaactg gtccgggacg gccagcgttg gcgacttcaa
     2401 aagcctccgc catgatgcgc ggcaactctg ccagcgactg caccaggaag ctgtgtttgg
     2461 tacaggccag cgacagccct aacacatcca cctcctggaa cgcatcggtg ccgatgaacg
     2521 gggcggaaac ctgacccgtg atcgcgacaa cggggaccga atctaacaac gcatccgcca
     2581 ggccagtgat caggttagtg gcgccagggc ccgaggtggc gatacaaaca ccggttttgc
     2641 cggtagaacg ggcataaccg attgccgcca ttgcggcacc ctgctcgtgt cggcacaaca
     2701 aatgctccac accaccgtca tacaacgcgt cgtaaaccgg cataattgcg ccgccaggat
     2761 aaccaaatac ggttttcacc ccctgcgctc gcaaagcatg taccacccac tgtgccccgt
     2821 tcatagttac atccccgtcg taaatcttga gaaacagaat tttatgctgt tattcacgct
     2881 ctgctcctcg cttaagtttt tcaggccaaa aaaaaccccc ggacctttcg gtgcgggggt
     2941 cttagttcgt taaggcttga tttctaagcc tttcctcgtc caagtgcagc cccgcacggt
     3001 gggataataa tcaccaccac gctaatcacg accaggctaa tcactcgtag aagggctgtc
     3061 atttttgtct attcttgcat cttgttcgaa ggaataccta aagagttacc ataggttttg
     3121 ccaatagcac aagatatttt tttaaccacg tttcagataa tgcaggtgaa tgcctaaaag
     3181 ggctttgttt tttataagaa aaattagcaa ctgaaaaatt ttcacgtttt cctccccctt
     3241 ttggtgcgct ttacaccctg ttttccttct tttcgcttct gcgagcgttc ttccagtttg
     3301 atgtttctta cctgaaaatg acgccaaaat tcaggaatca gccgctaaaa aacaaaaagt
     3361 cagtaattcg attttctctt ctattccgca taatccacgt aacaggaggg attatgtcac
     3421 tggcgattgt tcatactcgc gccgcacttg gcgtcaatgc gccgcctatc actatagagg
     3481 tgcatatcag taatggatta ccgggattaa ccatggttgg cctaccggaa accacggtaa
     3541 aagaggtgcg tgaccgggta cgtagtgcga ttattaatag cggatatgaa tttccggcta
     3601 aa
//
LOCUS       DAJVKX010000235         3538 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.236, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000235 DAJVKX010000000
VERSION     DAJVKX010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3538
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.236"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            214..1071
                     /gene="focA"
                     /locus_tag="OPY25_004435"
     CDS             214..1071
                     /gene="focA"
                     /locus_tag="OPY25_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HCS0929868.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGAMPYGMAKLIGGICFSLGLILCVICGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLIGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKMHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFATPEFWTAVGSSPESFSHLTVMSFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRGNEHH"
     gene            1131..3413
                     /gene="pflB"
                     /locus_tag="OPY25_004436"
     CDS             1131..3413
                     /gene="pflB"
                     /locus_tag="OPY25_004436"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCS0929869.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATDATTKLWDSVMEGVKQENRTHAPVDFDTSVASTITSHDAGYINKALEKIVGLQT
                     EAPLKRAIIPFGGIKMVEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKFAQFTSLQSDLENGVNLEATI
                     RLREEIAEQHRALGQIKEMAAKYGCDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRVSTFLDAYIERDLKAGKITEQDAQEMIDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGVDGRTLVTKNSFRFLNTLYTMGPSPEPNITVLWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNFDEVMDRMDHFMDWLAKQYVTALNVIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDARVDDMAVDLVERFMKKIQKLTTYRGAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMEHPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQTM"
BASE COUNT          903 a          874 c          861 g          900 t
ORIGIN      
        1 accgtgcagc aggaggagcc aggaaaaaat tcaactctat ttataatttt taaaatttat
       61 ttttattagg ataatcaaaa agttacaccg taattgcata aaagccatgc gacttacggg
      121 cctataagcc aggcgagata tgatctatat caaattctca tctataatgc tttgttagta
      181 tctcgtcgcc gacttaataa agagagagtt agtgtgaaag ctgacaaccc ttttgacctt
      241 ttactccctg cagcaatggc caaagtggct gaagaagcag gcgtctataa agcaacgaaa
      301 catccgctta agactttcta tctggcgatt accgccggcg tattcatttc aattgccttt
      361 gttttttata ttactgcgac aaccggtact ggcgcgatgc cttatggcat ggcgaaactt
      421 atcgggggta tctgtttctc tttgggactg attctctgtg ttatttgcgg cgctgatctt
      481 ttcacctcta ctgttctgat cgttgtagct aaagctagcg gtcgcatcac ctggggacaa
      541 ctggctaaaa actggttaaa cgtctatttt ggtaacctga ttggcgctct gcttttcgtg
      601 ttactgatgt ggctttccgg cgagtatatg actgccaacg gtcaatgggg acttaacgtc
      661 ctgcaaaccg ccgaccacaa aatgcaccac acttttattg aagctgtctg cctcggtatt
      721 ctggcgaacc tgatggtttg tctggccgtg tggatgagct actcaggtcg tagcctgatg
      781 gacaaagcgt tcatcatggt actgcccgtc gccatgtttg tcgccagcgg ttttgagcac
      841 agtatcgcaa acatgtttat gattcctatg ggtattgtaa tacgcgattt cgctacaccg
      901 gagttttgga ccgcggttgg ttcgtctccg gaaagttttt ctcacctgac cgtgatgagc
      961 ttcatcactg ataacctgat tccggtcacg atcggtaata ttatcggcgg cggtttgttg
     1021 gtcgggttga catactgggt catttacctg cgtggtaacg agcatcatta atctgttgat
     1081 gtccattaca cgcagtaaat aaaaaatcca cttaagaagg taggtgttac atgtccgagc
     1141 ttaatgaaaa gttagccaca gcctgggaag gttttaccaa aggtgactgg cagaatgaag
     1201 taaacgtccg tgacttcatt cagaaaaact acactccgta tgagggtgac gagtccttcc
     1261 tggctggcgc tactgacgcg accaccaagc tgtgggacag cgtaatggaa ggcgttaaac
     1321 aggaaaaccg cactcacgcg cctgttgact ttgacacctc cgttgcttcc accatcactt
     1381 ctcacgacgc tggctacatc aacaaagcgc ttgagaaaat tgttggtctg cagactgaag
     1441 ctccgctgaa acgtgcgatt atcccgtttg gcggcatcaa aatggttgaa ggttcctgca
     1501 aagcgtacaa tcgcgagctg gacccaatga tcaaaaaaat cttcaccgaa taccgtaaga
     1561 cccacaacca gggcgtattc gacgtttata ctccggacat cctgcgttgc cgtaagtccg
     1621 gcgtgctgac cggtctgccg gatgcgtatg gccgtggccg tatcatcggt gactaccgtc
     1681 gcgtagcgct gtacggtatc gactacctga tgaaagacaa attcgcgcag tttacgtctc
     1741 tgcaatccga tctggaaaac ggcgtaaatc tggaagcgac tatccgtctg cgtgaagaaa
     1801 tcgctgaaca gcaccgcgct ctgggtcaga tcaaagaaat ggcagctaaa tacggctgcg
     1861 atatctctgg cccggcgact aacgctcagg aagcaatcca gtggacttac ttcggttact
     1921 tggctgcggt taaatctcag aacggcgcag caatgtcctt cggtcgtgta tccaccttcc
     1981 tggatgcgta catcgaacgt gacctgaaag caggcaaaat caccgagcaa gacgcacagg
     2041 aaatgattga ccacctggtc atgaaactgc gtatggttcg cttcctgcgt actccggaat
     2101 atgatgaact gttctccggc gacccgattt gggcaaccga atctatcggc ggtatgggcg
     2161 ttgatggccg tactctggtc accaaaaaca gcttccgttt cctgaacacc ctgtacacca
     2221 tggggccgtc tccggagccg aacatcaccg ttctgtggtc tgaaaaactg ccgctgaact
     2281 tcaagaagtt cgccgctaaa gtctccatcg acacctcttc tctgcagtac gagaacgatg
     2341 acctgatgcg tccggacttc aacaacgatg actacgctat cgcatgctgt gtaagcccga
     2401 tgatcgttgg taaacaaatg cagttcttcg gcgcgcgtgc aaacctggcg aaaaccatgc
     2461 tgtacgcaat caacggcggc gttgatgaaa aactgaaaat gcaggttggt ccgaaatccg
     2521 aaccgatcaa aggcgatgtt ctgaacttcg acgaagtgat ggatcgcatg gatcacttca
     2581 tggactggct ggctaaacag tatgtcaccg cactgaacgt tatccactac atgcacgaca
     2641 agtacagcta cgaagcctct ctgatggcgc tgcacgaccg tgacgttatc cgcaccatgg
     2701 cgtgtggtat cgcaggtctg tccgttgcgg ctgactccct gtctgccatc aaatatgcga
     2761 aagttaaacc gattcgtgac gaagatggtc tggctatcga cttcgaaatc gaaggcgaat
     2821 acccgcagtt tggtaacaac gacgctcgtg tagatgacat ggcggttgac ctggtagaac
     2881 gtttcatgaa gaaaattcag aaactgacca cctaccgtgg cgctatcccg acgcagtctg
     2941 ttctgaccat cacttctaac gttgtgtatg gtaagaaaac cggtaacacc ccggatggtc
     3001 gtcgcgctgg cgcgccgttc ggaccaggtg ctaacccgat gcacggtcgt gaccagaaag
     3061 gcgctgtcgc ttctctgacc tccgttgcta aactgccgtt tgcttacgcg aaagatggta
     3121 tttcttatac cttctctatc gttccgaacg cactgggtaa agacgacgaa gttcgtaaga
     3181 ctaacctggc aggtctgatg gatggttact tccaccacga agcgtccatc gaaggcggtc
     3241 agcacctgaa cgtcaacgtc atgaaccgtg aaatgctgct ggacgcgatg gaacatccgg
     3301 aaaaatatcc gcagctgacc atccgtgtat ctggttacgc agtacgtttt aactccctga
     3361 cgaaagaaca gcagcaggac gttattactc gtaccttcac gcagaccatg taatgggttt
     3421 gactgaaatt acgccataaa aagcgtacaa aaaaggctcc atatcagtgg ggccttttta
     3481 atgacttttt atataagcat attgcgacaa ctagaatttt cacttataaa taaagtgt
//
LOCUS       DAJVKX010000236         3487 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.237, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000236 DAJVKX010000000
VERSION     DAJVKX010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3487
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.237"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            7..876
                     /locus_tag="OPY25_004437"
     CDS             7..876
                     /locus_tag="OPY25_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCS0929870.1"
                     /translation="MEYSILSNNLKMPMVGFGVFKVTDKEECQQSVLSAIRSGYRLID
                     TAAVYGNEDAVGDAVREAIATGLCTREELFITSKLWVQDMANYDLAKAGIEASLKKSG
                     LDYFDLYLLHQAMGDYFSAWRALEDAYEAGKLKAIGVSNFYAHVLANFCETVRITPMV
                     NQVELHPYFAQPAALETMKHYNVQPEAWAPLGGGRHKPYENVMLQRIADAHQKTIAQV
                     VLRWNVQRGVTVIPKSTRQERIEENFAIWDFSLTDNEMAQINALDLGYVGEAVKHFNP
                     EFVRGCLGVKIHD"
     gene            complement(967..1680)
                     /gene="bdcA"
                     /locus_tag="OPY25_004438"
     CDS             complement(967..1680)
                     /gene="bdcA"
                     /locus_tag="OPY25_004438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCS0929871.1"
                     /translation="MMLFRNKSVLVLGGSRGIGAAIVRRFSADGASVVFSYAGSREAA
                     EKLAAETGSTAIQTDSADRDAVISLVREYGPLDILVVNAGVALFGDALEQDSDAIDRL
                     FRINIHAPYHASVEAARNMPEGGRIIIIGSVNGDRMPIPGMAAYAASKSALQGLARGL
                     ARDFGPRGITINVVQPGPIDTDINPEDGPMKELMHSFMAIKRHGRPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            1758..2348
                     /locus_tag="OPY25_004439"
     CDS             1758..2348
                     /locus_tag="OPY25_004439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCS0929872.1"
                     /translation="MTTKHSRTPGRPRQFDPEQSIETAQHLFHSRGYDAVSVADLTKA
                     FGINPPSFYAAFGSKLGLYTRVLKRYRMTDAIPLGALLRHDRPTAKCLIDVLMEAARR
                     YAADPDATGCLVLEGAHCNDKPAREAACEFYIAAENLIRTYVAMRYPQEADRTTDFMG
                     TLMAGLSAKARAGYSLERLQESVLLAGDVLERLLPD"
     gene            2477..2713
                     /locus_tag="OPY25_004440"
     CDS             2477..2713
                     /locus_tag="OPY25_004440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCS0929873.1"
                     /translation="MQKCSLITVLSLSVLMLAGCTTTYTMTTRTGEIIETQGKPEVDT
                     ATGMTKYADVYGYHRVIKTSEIVQTTEGASKLDW"
     gene            complement(2927..3304)
                     /locus_tag="OPY25_004441"
     CDS             complement(2927..3304)
                     /locus_tag="OPY25_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001623945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929874.1"
                     /translation="MLSPRFFDNSMSKEAKVKRLKAVLNTFSQNRVTFYMSKEMLANL
                     KEFDLPVQLSPSYAELMRMPWASATRHFASVDQYNLFADLIPKVTPFLLEPNDADQAL
                     YATDYLNTRRVSLTQNILNHGCD"
BASE COUNT          874 a          823 c          919 g          871 t
ORIGIN      
        1 tttagcgtgg aatattcaat attaagtaac aaccttaaaa tgcctatggt gggttttggc
       61 gtttttaagg taaccgacaa agaagaatgt cagcagtcag tgttaagcgc tattcgcagc
      121 ggttatcgtc ttatcgatac cgctgcggta tacggcaatg aagatgccgt tggtgacgct
      181 gttcgtgaag ccatcgcgac aggtctgtgt acccgtgagg agttatttat tacttctaaa
      241 ctgtgggtgc aagatatggc taactacgat ctggccaaag caggtattga agcgtcgctg
      301 aaaaaatccg ggttagatta ttttgatctc tatttattgc atcaggcaat gggcgattat
      361 tttagcgcgt ggcgcgcgct ggaagacgct tatgaagccg gtaaactaaa agccattggc
      421 gtgtccaact tctatgcgca tgtgttagcc aacttctgtg aaaccgtcag aattacgcca
      481 atggtaaacc aggttgaatt gcatccatac tttgcacaac ccgccgcgct ggaaaccatg
      541 aagcattata acgttcagcc tgaagcgtgg gcaccgttag gcggcgggag acataaaccg
      601 tatgaaaatg tcatgcttca aaggattgcc gatgcccatc aaaaaaccat cgcgcaggtt
      661 gtcctgcgtt ggaacgtgca gcgtggcgtc acggttattc ctaaatccac tcgacaggaa
      721 cgtattgaag agaactttgc catctgggat ttctcactaa cggataacga aatggctcaa
      781 atcaacgccc ttgatttagg ctacgttggc gaagcggtga agcattttaa tcctgaattt
      841 gttcgcggtt gtcttggcgt taaaatccac gattgatccc ggcgcttgcg gatgttttct
      901 cgcatgaaca gcttctaaca cggttgccgg agcgtagacg gcaaccgtgt gatattcgcc
      961 tggccgtcag gcgccgaagg caccatcgat ggtgtgcatc gcgccggtga cgaaagaagc
     1021 ttccggaccg gcaagccatg ccaccattcc agccacttct tcaggtcttc cgtgtcgttt
     1081 gattgccatg aaactgtgca tcagctcttt catggggcca tcttccggat tgatgtcggt
     1141 atcaatgggg cctggctgca ccacatttat cgtaatcccg cgggggccaa aatcacgggc
     1201 caggccgcgc gccagccctt gcagggctga tttactggca gcgtacgcgg ccattcccgg
     1261 tatgggcatc cgatcgccat tcacggaacc gataataata atgcgtccac cttccggcat
     1321 gttgcgggct gcttcgactg acgcatggta aggcgcatgg atattaatac ggaacaaacg
     1381 atctatcgca tcgctatctt gttccagcgc atcgccgaag agagccacgc ccgcattgac
     1441 gaccagaata tccagtggtc cgtactcacg cacgaggctg atgacggcat cccgatcggc
     1501 gctatccgtc tggatggcgg tgcttccggt ttccgctgcc agtttttcgg cggcttcacg
     1561 cgatccggcg tagctgaaaa cgaccgatgc gccgtcagcg ctaaagcgtc gtacaatagc
     1621 cgcgccgata ccacgacttc cccctaaaac cagtacagat ttgttgcgaa atagcatcat
     1681 caggatgtcc tttatgatat tgtagtagtc actacaatat gcgtaatgaa atcatgccgt
     1741 caaggagtta tgtagtaatg actacaaaac atagccgaac gccgggtcgc cctcgccagt
     1801 tcgatccgga gcaatccatt gaaaccgctc aacacttatt tcattcgcgc ggatacgacg
     1861 cggtgagcgt agcggatctg acaaaagcgt tcgggatcaa tcctcccagt ttctatgcgg
     1921 cgtttggcag caagctgggg ctgtatactc gcgtattaaa gcgttacagg atgaccgacg
     1981 cgattccgct cggggcgctt ctgcgtcacg atcgcccgac cgcgaagtgt cttatcgatg
     2041 tgctgatgga agcggcaaga cgttacgctg ccgatcctga tgccaccgga tgtctggttc
     2101 tggagggcgc tcattgtaac gataaaccgg cacgagaggc cgcctgcgag ttttacatcg
     2161 ctgctgaaaa cctgattcgc acttatgtcg ccatgcggta tccgcaagag gctgaccgga
     2221 cgacggactt tatggggacg ctaatggcgg gactttccgc caaggcgcga gcggggtata
     2281 gcctggagcg tcttcaggag agcgtgcttc tggctgggga tgtgctggag cgattactgc
     2341 cggattaacg cagcgcatca aaaaacctga gccagtcaga tacggacaaa cagggagcaa
     2401 tagccctaat catccatctt gccgttgcgg tattcggtaa agtacatcaa aaatagaggt
     2461 gtcagggaaa caagaaatgc aaaagtgtag tcttattacg gtacttagct tatcagtgtt
     2521 gatgctagcc ggatgtacaa cgacctatac catgacgacc cggacgggag agattattga
     2581 aacgcagggt aagccggagg ttgacaccgc aaccggaatg acgaaatacg ctgatgttta
     2641 tggttatcat cgcgttatta aaaccagtga aatagtgcag acgacagaag gcgcatcgaa
     2701 gctggactgg taatgcgcta aagcagttgg gaggccgtgt ccagtatggg taccggactg
     2761 tttctgggcc tgaattgaat agagcgcctg tatagccgaa ttccgggtct cggcttgatt
     2821 tgtgttgtca gttatttggt tgttccctgt atagtgaaga taaacagtac tcatggctaa
     2881 cggtctgttt tggattgcta actatcccgg attctgcgcg ttttatttag tcacaaccat
     2941 ggttaagaat attttgggtc agacttacac gccgggtatt aagataatcc gtcgcataga
     3001 gagcttgatc ggcatcattc ggttcaagaa gaaacggcgt gactttaggt atgagatcag
     3061 caaacaggtt atattgatcc acagaggcaa aatgccgggt agcgctggcc cagggcattc
     3121 gcatcagctc tgcgtaagaa ggggatagtt gaacaggcaa atcaaattct ttcagattag
     3181 caagcatctc cttactcata taaaatgtga ccctattttg cgaaaaggtg ttaagcactg
     3241 ccttcagtcg tttaactttt gcttctttac tcatgctatt atcaaaaaaa cgtggtgaaa
     3301 gcataatagc aatcgatgca tttggtgaaa taacattatg tagtggtttc agggctacaa
     3361 caatctgatc gtttgtgaag atacgctgcg taccagaaga ggtagtatag tttccaccca
     3421 gccagatcac ataatccgtt gttttgaggg gaagcgcttt ttccggtata ttacccctgt
     3481 caggtgc
//
LOCUS       DAJVKX010000237         3459 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.238, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000237 DAJVKX010000000
VERSION     DAJVKX010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3459
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.238"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(78..398)
                     /locus_tag="OPY25_004442"
     CDS             complement(78..398)
                     /locus_tag="OPY25_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929875.1"
                     /translation="MATSNYNINGQTGTADALSGMNTNNSPFLHTPADGSRKFTTFEV
                     GHDRAFDSEVKIFEHIANKFPTTAKGRIDLYSELKVCPSCSEVITQFKAMYPNIEVNV
                     TWGG"
     gene            complement(483..2987)
                     /locus_tag="OPY25_004443"
                     /pseudo
     CDS             complement(483..2987)
                     /locus_tag="OPY25_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            2987..3310
                     /locus_tag="OPY25_004444"
     CDS             2987..3310
                     /locus_tag="OPY25_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001651551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system SymE family toxin"
                     /protein_id="HCS0929876.1"
                     /translation="MPDFTHCEFYSRVEGRSVRLCGEWMPQAGFINGVPVKIRVMKDC
                     IVITLQNTRELLGCIEGMGVTYINQRNVKAWLKDFPGALNDTGDIPVMSRDLQCITTN
                     CRFAH"
BASE COUNT          625 a         1164 c          822 g          848 t
ORIGIN      
        1 ccttgacagt catgtttttt gacgttatcg atgcaattaa cttcttaatt tcaatcaaaa
       61 aagctcgctg ttccatatta ccctccccat gtcacattaa cttcaatatt aggatacatt
      121 gctttgaatt gagttataac ctctgaacat gaggggcata cttttaattc cgagtataga
      181 tcaatacgac cttttgccgt tgttggaaat ttattggcta tatgttcaaa tattttaact
      241 tcagaatcga aagccctgtc atgccccact tcgaaggtag tgaactttcg acttccgtct
      301 gctggagtat gtaaaaatgg tgaattattc gtattcatgc cactaagtgc atcagccgtt
      361 cctgtttgac cattaatatt ataattggat gttgcaatat ttcgttttcc acctacctag
      421 ccagtgcttc tataattcct ggccctttct gccggagaac ctttaccagc aaatttttta
      481 cataaaccta gcggatctat ataacttagc ggattaggcg catattggta gaggtttatt
      541 ccacccgcta accctatcgg atcgcccgat ataaacttcc cgatatccgg atcataaaat
      601 ctgtacaaat tgtaatgcag ccccgtttcc ctgtccagat attgcccctg gaaacgcagg
      661 ttctgctgta cgggccgggt ttctttttca tgcgtcaggt tcccccatac ctgatagccc
      721 gcttcccaga caatattgcc cccgccgtcc gtcatctcct ccggcgcgcc gtttacgtcc
      781 gtatggtaat acagcacctc atccgcttcg cccggcgccg ccctgtccac ccgcgccagc
      841 ggctcgtggc tcccccggtc gctgtagata tacaggctgc tgcttcttcc cagcctgcac
      901 tcctgtgcca gccgcattcc gtcccataaa aacgtcgtcc ggttatacgg ctttccttcc
      961 gcgtccagct cgtgcttctc cacccgcctg cccggcgcgt cgtacacgta cccgtaacgc
     1021 cgtacggtgc ccccccgggt gaccgccact tccgtcagcc ggtgctccgc gtcccagcgg
     1081 tagtgctgcg tgccgttgcg gccccgcttt tccaccaccc ggccatattc atcgtaacgg
     1141 taatgcagcc cgcgatatga cgttatccgg ttgaacggca ccacgctgcc tgcacccgcc
     1201 tgcgcggtct ctccctgccg cctgtccagc aggttcgccg ccgcgtcgta ctgccagctg
     1261 tccaggtatg cctcattccg gcacgccgtg atgcgccccg tcgtgtcgta aaaataatcc
     1321 gtcaccccct gccggctgtg ccgctttttc agcagctcat cctggccgct gtacgcatat
     1381 tcccggtcaa taaacgtctc cggcaccaca ccgcgcattc ctttacaggt cagtttccgc
     1441 gttaaccggc ccgtccggtc gtacatccgc cgcatgtcca gccgcccctg gctccgctgc
     1501 acctcacggt gcaggtggtc gcgcgtgaac tcgctgatga catcacgccc caggttgatt
     1561 tgctggagat gtccgctccc gtagtacagg taccgcagcg tccgcccgtc cggcatctgc
     1621 gtttctgtgc ggttgccctg aacatcgtac cggtgctgca gcacgccctg cgccgtctcc
     1681 tcgctcagca ggttacccgc actgtcgtag ctgaaccgga taacttccgg ctctccgcct
     1741 tccgccgcat catgccgcct gcggcggatt tccagcagac ggtccgccgc gtcgtaccgg
     1801 tattccgtgc gcgtctccgg cgtgattttc gccgtcagcc tccccgccgc atcacgctcc
     1861 agaccgtggc ggatttctcc cccgcgctcc ccgccgtata tcactgccgt caccgcattc
     1921 agcgcgttat acccgtatgc ccggcggctg ccgccggggt ccgtctgttc cgtcacccgg
     1981 tccagaacat cgtaccggaa ccggtagctt tccccgttct cgttcgtgag cgtggtcagc
     2041 cgcccgtaag cgtcgtactc atacgccgtc ctgcgacccg tcgcatccgt ctgcctgcgc
     2101 acccgcccct ggccgtcccg ctgccagcgt gttatttgcc ccgccgggct cgtatatttc
     2161 accagccgtc ccgccgcatc cggctggtaa cgctccgtac gcccgtccgc gaacatgacc
     2221 tccgtcagat gtccgttgcc gtcatagctg taacgcgtac tgttactctc cgcgtccgtc
     2281 accctttcca gccgcgtgcg ttcatcataa aaccatgccg tctgcgagcc agaacagtcc
     2341 gtgtggcgca taagctgtcc gtcttcgttc cactgcaggt atttatctcc gccccgcgcg
     2401 tcggttatcc gcaccacctg gccgtgccgg tcatacccgt ataccgtgcg ctggtgcagc
     2461 gggtcgctga ccgcctgcag gttgccccgc tcatcatact cataacgcca cgccaccccc
     2521 gcggcatcca cctccgtttc cggctggtgc cacaccgggt gccactgcgt ctgctcaacc
     2581 cggcccagcg ggtcatgcgt ctccgtcagg tggccgagac ggtcatagac ataacgccat
     2641 ttgccaccct gcgcgtccgt catccccagc agtaaccgct cttcatcgct ccagcggaaa
     2701 gtggtcatct gcccggcctc gtcccggtac gccgtcacca ggccctgcgc atcccaccag
     2761 tggcagcgcg tacgccccat gctatccgtc acgcacagcg aacgttctgc cagattccag
     2821 tccagacggt actgctcgcc gctgtccgta tgatggcccg tcacccgcca cgccgcatcg
     2881 tccgggcctt caaaccacgc ccaggtgtag taataccgtt cgccgcccgg ctcccggtgc
     2941 atcgtcatgc agtcgttgtc gtcgtacgca aactcgcgct gatactgtgc cggattttac
     3001 ccactgtgag ttctattcac gggttgaggg acgttcagtt cgtttatgcg gtgaatggat
     3061 gccgcaggcc gggtttatta acggagtgcc cgttaaaatt cgggtgatga aagactgcat
     3121 cgtgatcacg ctgcaaaata cccgtgaact gttgggctgt attgaaggga tgggcgtgac
     3181 ctatatcaac cagcgaaacg ttaaagcatg gctgaaagat tttcccggtg cgctgaatga
     3241 caccggggat attccggtga tgagtcggga tcttcagtgt attactacca attgccggtt
     3301 tgctcactaa caacagaaaa aacaacatcg cggtcatcaa atatcccgtg tcagtctatg
     3361 gattcatttc catttcagtg tcatcaacat gcagcccgac aatcccggcg tcctgtattg
     3421 catcgatcag tctgtcagaa aaaaatagcc ctttcccct
//
LOCUS       DAJVKX010000238         3371 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.239, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000238 DAJVKX010000000
VERSION     DAJVKX010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3371
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.239"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(122..802)
                     /locus_tag="OPY25_004445"
     CDS             complement(122..802)
                     /locus_tag="OPY25_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCS0929877.1"
                     /translation="MIAGWSLFFNDLTEQLPLVVDGIKETCKLALIVSITGFLWGIII
                     FFLSLSHRPVVKAITRLYMDFFIGTPLILILFVIYYGLPQSGIHLSSFTVAVTGFTLN
                     VGAYNAAYMTTAYNALNKYETEAAVVQGLNKRQVFLWIILPQVLLSSIPALTNQVINN
                     LKDSTIVFLIQYTEFFARIQEVAATSFKFFHAYLFAAIVYLIGVTFIVGLTRFLEHRL
                     LRHYGQDY"
     gene            complement(799..1530)
                     /locus_tag="OPY25_004446"
     CDS             complement(799..1530)
                     /locus_tag="OPY25_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCS0929878.1"
                     /translation="MALLELKEISKEYSGKKVLDAVSLKIQSGDMKVVMGPSGCGKTT
                     LLRCLLRLEEPDYGDIYFHGENIYDKEFTILEFRKKVGCVFQNYALYRHLNVMDNITL
                     ALCKVFGMPGQLAREKALHELQKLDMVSHSAKYPSQLSGGQQQRVALARTMVTDPELI
                     IFDEPTSALDPLMTREVGMLIKQLHDNGVTILCVTHDIRLARLLSDNVTFLNHGKIRA
                     EGAFTDLALRETDPDIHCFFSEAQR"
     gene            complement(1555..2202)
                     /locus_tag="OPY25_004447"
     CDS             complement(1555..2202)
                     /locus_tag="OPY25_004447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCS0929879.1"
                     /translation="MSSGNMLAIFYFLLEGIGNTLLVTFTCFLSAFLTGLTVAVLRRL
                     SPLPLQKILDVLVFILRGIPILIAVFLVYFGLPSIGIYVSPLVAMNLSVGLISGSYLA
                     EVFRGALKLVEPFEITVAKVAGMRQLQVIINIELPQMLRFSVPGIINEFSSVLKATPF
                     AYTVGIAEITKQAMSLTAITLNGLQIYTLAGVLYFIIYKAFTLLAGVFEKKYRIS"
     gene            complement(2209..2970)
                     /locus_tag="OPY25_004448"
     CDS             complement(2209..2970)
                     /locus_tag="OPY25_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCS0929880.1"
                     /translation="MLSKKIGLSMIVLGIMSSSAFADSIVEGRTLNVAVSPASPPMLF
                     KSADGKLQGIDLELFSSYCQSRHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKR
                     KKVIDFSEPYYINSFYLVSMANHKITLNNLNELNQYSIGYPRGMAYSDLIKNDLEPKG
                     YYSLSKVKLYPTYNETMTDLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQL
                     GIAFKKGSPVRDDFNLWLKEQGPQKISGIVDNWMK"
BASE COUNT         1066 a          699 c          680 g          926 t
ORIGIN      
        1 gtaagactta gaccagaatg gacacctaac gcaataatga aggttaaaat cttaaccaac
       61 actaaataaa aataactttg ataatgtcag cggtgaatta atcagaatag tgcagtacaa
      121 ctcagtaatc ctgaccgtaa tggcgaagca gtctatgctc taaaaaccgg gtcaaaccga
      181 caataaaggt aacgccaata aggtacacta tggcggcaaa aaggtaagca tggaagaatt
      241 taaagctggt tgcagcaacc tcctgaattc gcgcgaaaaa ctcagtatat tggataagaa
      301 aaacgatggt gctgtcttta aggttattaa tcacctgatt cgttaaggct ggaatggaag
      361 acagcaatac ctgaggcagt ataatccaca aaaagacctg ccgtttgttc aacccctgaa
      421 cgactgctgc ctccgtttca tacttattca atgcgttata ggccgttgtc atgtacgcgg
      481 cattatatgc gccgacattc aaggtaaaac ctgtaaccgc cacggtaaaa gaggacaggt
      541 gaatgccaga ttgaggtaaa ccataataga taacaaacag aataagaatg agtggcgtac
      601 cgataaagaa atccatgtac agtcgagtta tggcttttac cacggggcga tggctcaggc
      661 tcagaaagaa aataataatt ccccacaaaa aaccggtgat ggaaacaatc agcgcaagtt
      721 tacaggtttc tttaataccg tccacaacaa gtggcagttg ttcagtcagg tcattaaaga
      781 aaagagacca gccagcgatc atcgttgtgc ctcgctaaaa aaacagtgga tatctggatc
      841 cgtttctcgt aaggcaagat cggtaaaagc gccttctgca cgaatcttgc catgattaag
      901 aaacgttacg ttatcgctta gtaatctggc gaggcgaata tcatgagtga cgcataatat
      961 agtgacgcca ttgtcgtgaa gttgcttgat caacattccg acttcacgag tcatgagcgg
     1021 atcaagcgca gacgtcggct catcaaaaat aatgagttct gggtcggtga ccattgtacg
     1081 ggccagggcg acgcgctgtt gctggccacc cgataattgc gaagggtatt tcgcgctatg
     1141 cgagaccata tcaagttttt gtagctcatg taaggctttc tcccgggcta gttgtcccgg
     1201 catcccaaac actttacata gggcaagggt aatattatcc atgacgttaa gatggcgata
     1261 caatgcgtaa ttctggaaga cacaaccaac tttttttctg aactcaagaa tagtaaattc
     1321 tttgtcgtaa atattttccc cgtgaaaata aatatcgcca taatcaggtt cttctaatcg
     1381 aagcagacag cgtaaaagcg tcgtttttcc acaacccgat ggccccatga ctactttcat
     1441 gtctcccgat tgaattttca aactaaccgc atcaagaacc ttttttcctg aatattcctt
     1501 acttatctct tttagttcca gtaaagccat gagtatcacc tctattttta tgtttcaact
     1561 gatgcgatat tttttctcaa acactccggc cagaagagta aatgctttat aaataatgaa
     1621 atataatacc ccggcaaggg tatagatctg taacccgttc agcgtgatgg ctgtcagtga
     1681 cattgcctgc ttcgttattt cagcgatgcc tacagtataa gcaaagggcg tcgcttttaa
     1741 tacagaagaa aactcattga taataccggg cacagaaaat cgcaacatct gtggcagttc
     1801 aatatttatt ataacctgta attgacgcat tcctgctact ttcgctaccg ttatttcgaa
     1861 tggctcaact aatttaagcg cccctctgaa cacctcggca agataactcc cgctgattaa
     1921 gccgacgctg aggttcatgg ccaccagagg tgaaacatat atgccaatcg atggcaatcc
     1981 aaaataaaca agaaaaacag caataagtat tggaattccc cgaagaataa agaccagtac
     2041 gtcgagtatc ttctgtagtg gaagggggga tagtcgccgt aatacggcga ctgtaagccc
     2101 ggtcaaaaac gctgagagaa aacaggtaaa ggttacaagc agcgtattac caatcccttc
     2161 caataggaaa taaaagatag ccagcatatt acctgatgac atagcttact atttcatcca
     2221 gttatcaacg atgccagata ttttttgtgg cccttgctct ttaagccata agttaaaatc
     2281 atcgcgcacg ggagagcctt tcttaaaggc aatgccaagc tgatcaacat tcttgaaaac
     2341 ataacgactt tctatcggca tttttttctt atttttgaag gtaaagtaaa ccggctcttc
     2401 tataaaagcc agatcaagat taccattttt tagatcagtc atcgtctcgt tataggttgg
     2461 atataatttt actttactta acgagtagta tcctttgggc tccagatcgt ttttgataag
     2521 gtcggagtaa gccattcctc gagggtatcc aatagaatat tgatttaatt cattgaggtt
     2581 attgagcgtt attttatgat tggccatact gaccagataa aaagagttga tgtaataagg
     2641 ttcagaaaaa tcaataactt tcttacgttt atctgtgatt gaaattcccg aaaatgctac
     2701 atcagcctga ccactcgcca ctgcgccaag cattccatcc caggcatatt cggtgatgtt
     2761 tagcttacaa tgccgtgact gacagtaaga cgaaaaaagc tccagatcta tcccctgcaa
     2821 tttgccatca gcacttttaa ataacatagg gggagaggcc ggtgatactg cgacattgag
     2881 tgttctccct tcaacgatgc tatcagcaaa agctgaagac gacattattc ccaacactat
     2941 catcgataag ccaatttttt tggataacat gctatctatt tcctgtggta aggtaatacg
     3001 tattataaat taagcattag agcgtgaacc tgacatttgc aggcgtaaag tacttaacgt
     3061 tatgtattcc atcgctgtta actaatttaa tcaggaggtt tgacaggaat catcaaaggg
     3121 aatggattga atataccatg agatatcaac tggatatgag tgcagcgacc caatgaaagg
     3181 tgaaaatgta aagataccat agacattagt atactggaca tagtttatgc tccatttacg
     3241 catacatatt tacatgataa gcagataaat gcttcagtga cggtgtattt aatgtctcta
     3301 agtatcatct taccactcta tccagggcca atataaagac ttatctttgc ttgtcaaata
     3361 cattttctga g
//
LOCUS       DAJVKX010000239         3342 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.240, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000239 DAJVKX010000000
VERSION     DAJVKX010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3342
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.240"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..1672
                     /locus_tag="OPY25_004449"
     CDS             <1..1672
                     /locus_tag="OPY25_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCS0929881.1"
                     /translation="SINQKIDTNNALVLNHNAIYEQRLAEITQSNTCDKAIVTVNPYG
                     TAPLSLYLGIWIDEAAALEINVVDSEATTEAVRYQYDVHPGANLIPVCGMVSAVNNQI
                     TLRLASQIVGQYTVMTDALPPTDSANVSLGFPIISVSCPAQQASLMEEGLYFSTYFDR
                     YNLAFDHNGIVRWYVSQEIPSYNFVRMDNGHFLATSQGINHCLNMYEFDIMGRVYTVY
                     LLDNEFHHSILPIENNLAIAPSEYSNGRPDGYSTGKDGVSIINLSTGLEVAYYDMLYV
                     MDYSRSPRPSGSAPGQDVSMDDWLHINQSYINEPNNLLICSGRHQSAIFGVNVDSGEL
                     RFIMANHEDWSDEFKQYLLTPVDDDGVPLYDLTSPGGIDAADKNFWTWGQHNIVEIPN
                     DEPGILEFMVFDNGNYRSREDAKSLLPLDNFSRVVQFKINLNTMTVTRPYEYGKTEVG
                     NRGYSSFVSAKHLLTNGHLVIHFGATTVDEFEHTITAQPGSSDLVDPDEGQQALGRLV
                     LQEINKETKEVLFEAMVTSGYFKNEETNGTNYRYDISAFRVYKMPLFA"
     gene            complement(1718..3289)
                     /locus_tag="OPY25_004450"
     CDS             complement(1718..3289)
                     /locus_tag="OPY25_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HCS0929882.1"
                     /translation="MVYMNKKFSISLLSLCIGLSSAISFSADARDITIYYTNDLHAHV
                     TPEIIPYVSKTRPVGGFAPISKIVKDAKAKEKDVFFFDAGDYFTGPFISTLTKGEAII
                     DILNTMPYDAVSVGNHEFDHGHENLVKQLSKLQFPVLLDNVFYSGTDTPLIKEPYTIV
                     EKDGFKIGVIGMHGVSAFYEAIAAGVREGVDCRDPIPYVKKQLEELKGKVDLTVLLAH
                     EGVPGMQSSAGEADVARALKTDVDMAKSLEGYGLNVLITGHAHKGTPEPIKVGDTLVV
                     STDAYTIELGKLVLDWNPETKKVDSYNGKLITMYADTYKPDPVTQAKIDEWDNKVKKI
                     TDEVVAHSPEVLTRSYGESAPTGNLITDALMATVPGADASFYNAGGIRTELPKGNITY
                     GDVLSMYPFTNDVMSMEISGKDLKSIMSHAADLKNGMLHVSKTVQFKYDSTKPLGQRI
                     VEFDIKGKPVEDNKLYTVALDSFIGKGGGGFTFTKGKNIKYIGIQTAPALVNYMKQVN
                     NIQPDHTMRVDDISK"
BASE COUNT          863 a          750 c          795 g          934 t
ORIGIN      
        1 gtcgattaac cagaaaatcg ataccaataa cgcattggtg ttaaatcata acgccatata
       61 tgaacaacga ttagcggaga tcacgcaatc taatacctgt gacaaggcca ttgtcaccgt
      121 aaatccctac gggaccgccc cgttgagtct ctatctggga atttggattg atgaagctgc
      181 cgcgcttgag atcaatgttg ttgatagcga agcgacgaca gaggcagtgc gttatcaata
      241 tgatgtacat ccgggcgcta accttattcc tgtgtgtggg atggtatccg cggtgaataa
      301 tcagattacc ctacgccttg cctcgcaaat tgtcgggcaa tatacagtaa tgactgacgc
      361 attaccgccc acggattcgg ctaacgtgag cctcggcttc cccattatta gcgtctcctg
      421 tcctgcgcag caggcctcgc tgatggagga agggctttat ttctctactt attttgatcg
      481 gtataatctg gcttttgatc ataacgggat tgtccggtgg tatgtaagtc aggaaatccc
      541 ttcttataat tttgtcagaa tggataacgg ccatttcctg gcgacgtcac agggaataaa
      601 ccattgtctg aatatgtatg aatttgacat tatgggacgg gtttatacgg tttatcttct
      661 cgacaatgag ttccatcact ccattcttcc cattgagaac aatctggcga ttgcgccttc
      721 agaatatagc aatggacggc cagatggtta ctcaaccggg aaagatggcg tttctattat
      781 taacttatct accggacttg aagtcgccta ttacgatatg ctgtatgtga tggattattc
      841 cagatcgccg cgtccttccg gaagcgcgcc aggtcaggac gtatcaatgg atgactggct
      901 gcatatcaac caaagctata ttaatgaacc caacaatttg ctgatctgtt ccggtcgaca
      961 tcagagcgcg atttttggcg taaatgtgga ttccggcgaa ctgcgcttta ttatggcgaa
     1021 ccatgaggat tggtctgacg aattcaagca atacttatta actcctgtcg atgatgatgg
     1081 cgtcccgctg tatgatctta cctcgccggg agggattgat gcggcagata agaatttctg
     1141 gacctggggg cagcataaca ttgttgaaat tccaaatgat gagcctggta ttctggagtt
     1201 tatggtcttt gataatggta actatcgttc acgcgaagat gcgaaaagtt tgttgccgct
     1261 cgataacttc agccgggtgg tgcagtttaa aataaaccta aacacgatga ccgtaacgcg
     1321 tccgtatgaa tatggtaaaa cggaagtcgg gaaccggggc tatagcagtt ttgtgagcgc
     1381 taagcattta ttgactaatg gtcacctggt tattcacttc ggcgcgacga cggttgatga
     1441 gtttgaacat accattaccg cgcaaccagg ctccagcgat cttgtcgatc cggatgaagg
     1501 gcaacaggcg ttaggtcgac tggtattaca agaaatcaat aaagagacga aagaggtctt
     1561 attcgaagcg atggtgacgt cgggctattt caagaacgaa gagacgaatg gcacgaatta
     1621 tcgttatgat atttctgcat ttcgggtata caaaatgccg ctgtttgcat aactaagtat
     1681 gttatgcggc cggttatcga ccgcataaca ttatggctta tttgctaata tcatccacgc
     1741 gcatggtgtg gtcaggttga atattgttaa cctgcttcat atagttaacc aacgccggtg
     1801 cggtttgtat ccctatatat ttgatatttt tacctttagt gaaggtaaat ccgccaccac
     1861 ctttaccgat aaaggaatcc agcgcgacgg tatagagttt attgtcttct accggtttgc
     1921 ctttgatatc aaattcaaca atacgctggc ccagcggttt ggtactgtca tatttaaact
     1981 ggacggtttt agatacgtgc agcataccgt ttttcagatc ggcagcgtgt gacatgatgg
     2041 atttcaggtc cttaccgctg atttccatgc tcatgacatc gttggtgaac ggatacatac
     2101 tcagcacatc accataggtg atattacctt taggcaattc ggtacggatg ccgccagcat
     2161 tatagaagga agcgtcggcg ccaggaacgg tagccatcag ggcatcggtg attaagttgc
     2221 cggttggcgc ggattcaccg taagaacggg tcagcacttc cggagagtgc gcgaccactt
     2281 catcggtaat tttcttaacc ttgttatccc attcgtcaat tttggcctgc gtgaccggat
     2341 ctggcttata agtatccgca tacatggtga tcaacttacc attgtagctg tccacttttt
     2401 tggtttccgg gttccagtca agcaccagtt tacctaattc gatggtgtac gcatccgtgg
     2461 aaacgacaag agtatcgccc actttaatcg gttctggcgt acctttatgc gcatggccgg
     2521 taatcaggac gttaagtcca tagccttcca gcgatttcgc catatcaacg tcggttttca
     2581 gtgcgcgtgc gacatcagcc tcgcccgcgc tggactgcat acccggcacg ccttcgtggg
     2641 cgagcagcac ggtcaggtca actttccctt ttaactcttc cagctgtttt ttcacataag
     2701 gaatcggatc gcggcagtca acgccttcac gcacgcctgc ggcaatcgct tcatagaatg
     2761 cggaaacgcc gtgcataccg atgacgccga tcttgaatcc atctttttcc acaatggtat
     2821 acggttcttt aattaatggc gtatctgtgc cgctgtaaaa aacattatcc aacaataccg
     2881 ggaattgcaa tttgctgagc tgtttaacca gattctcatg gccatggtca aattcatggt
     2941 taccgacaga gacggcgtcg taaggcatgg tatttaaaat atcaataata gcctcgcctt
     3001 tggtcagcgt actgataaaa ggtccggtga aatagtcgcc agcatcaaag aaaaagacat
     3061 ctttctcttt cgcttttgca tctttgacaa ttttcgagat gggcgcaaag ccgcctaccg
     3121 gacgtgtctt ggatacatag gggataattt ctggggttac atgggcatgt aaatcgttcg
     3181 tataataaat tgtgatgtca cgcgcatcgg ctgaaaagga aatggctgaa gacaaaccaa
     3241 tgcacagcga cagtagggat atcgaaaact ttttgttcat ataaaccatc catttacgct
     3301 acattaaaga aaaacaatgc ctgtagtcgt gtcattcacg ac
//
LOCUS       DAJVKX010000240         3198 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.241, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000240 DAJVKX010000000
VERSION     DAJVKX010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3198
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.241"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            102..3107
                     /locus_tag="OPY25_004451"
     rRNA            102..3107
                     /locus_tag="OPY25_004451"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          850 a          705 c          991 g          652 t
ORIGIN      
        1 tcaagctgaa aattgaaaca cagaacaacg aaagttgttc gtgagtctct caaattttcg
       61 caacacgatg atgaatcgaa agaaacatct tcgggttgtg aggttaagcg actaagcgta
      121 cacggtggat gccctggcag tcagaggcga tgaagggcgt gctaatctgc gataagcgcc
      181 ggtaaggtga tatgaaccgt tataaccggc gatacccgaa tggggaaacc cagtgtgatt
      241 cgtcacacta tcattaactg aatccatagg ttaatgaggc gaaccggggg aactgaaaca
      301 tctaagtacc ccgaggaaaa gaaatcaacc gagattcccc cagtagcggc gagcgaacgg
      361 ggaggagccc agagcctgaa tcagcatgtg tgttagtgga agcgtctgga aaggcgcgcg
      421 atacagggtg acagccccgt acacaaaagc gcatatgctg tgagctcgat gagtagggcg
      481 ggacacgtgg tatcctgtct gaatatgggg ggaccatcct ccaaggctaa atactcctga
      541 ctgaccgata gtgaaccagt accgtgaggg aaaggcgaaa agaaccccgg cgaggggagt
      601 gaaaaagaac ctgaaaccgt gtacgtacaa gcagtgggag ccccaccact aagccagtgg
      661 tgaactccac atacgcatcc tttgctgagg agacggttaa cggagcgaaa gcgacgttca
      721 acctcaaaag aagcagaggg ggcttagtgg tggggtgact gcgtaccttt tgtataatgg
      781 gtcagcgact tatattctgt agcaaggtta actgtatagg ggagccggag ggaaaccgag
      841 tcttaaccgg gcgttaagtt gcagggtata gacccgaaac ccggtgatct agccatgggc
      901 aggttgaagg ttgggtaaca ctaactggag gaccgaaccg actaatgttg aaaaattagc
      961 ggatgacctg tggctggggg tgaaaggcca atcaaaccgg gagatagctg gttctccccg
     1021 aaagctattt aggtagcgcc tcgtgaattc atctccgggg gtagagcact gtttcggcta
     1081 gggggccatc ccggcttacc aacccgatgc aaactgcgaa taccggagaa tgttatcacg
     1141 ggagacacac ggcgggtgct aatgtccgtc gtgaagaggg aaacaaccca gaccgccagc
     1201 taaggtccca aagtcatggt taagtgggaa acgatgtggg aaggcccaga cagccaggat
     1261 gttggcttag aagcagccat catttaaaga aagcgtaata gctcactggt cgagtcggcc
     1321 tgcgcggaag atgtaacggg gctaaaccat gcaccgaagc tgcggcagcg acaccgtgtg
     1381 ttgttgggta ggggagcgtt ctgtaagcct gtgaaggtgt gctgtgaggc atgctggagg
     1441 tatcagaagt gcgaatgctg acataagtaa cgataaagcg ggtgaaaagc ccgctcgccg
     1501 gaagaccaag ggttcctgtc caacgttaat cggggcaggg tgagtcgacc cctaaggcga
     1561 ggccgaaagg cgtagtcgat gggaaacggg ttaatattcc cgtacttggt gttactgcga
     1621 aggggggacg gagaaggcta tgttggccgg gcgacggttg tcccggttta agcgtgtagg
     1681 tatgtgttcc aggtaaatcc ggttcacttt aacactgagg cgtgacgacg aggcactacg
     1741 gtgctgaagc aacaaatgcc ctgcttccag gaaaagcctc taagcatcag gtaacatcaa
     1801 atcgtacccc aaaccgacac aggtggtcag gtagagaata ccaaggcgct tgagagaact
     1861 cgggtgaagg aactaggcaa aatggtgccg taacttcggg agaaggcacg ctgacacgta
     1921 ggtgaagtga tttactcacg gagctgaagt cagccgaaga taccagctgg ctgcaactgt
     1981 ttattaaaaa cacagcactg tgcaaacacg aaagtggacg tatacggtgt gacgcctgcc
     2041 cggtgccgga aggttaattg atggggtcag cgcaagcgaa gctcctgatc gaagccccgg
     2101 taaacggcgg ccgtaactat aacggtccta aggtagcgaa attccttgtc gggtaagttc
     2161 cgacctgcac gaatggcgta atgatggcca ggctgtctcc acccgagact cagtgaaatt
     2221 gaactcgctg tgaagatgca gtgtacccgc ggcaagacgg aaagaccccg tgaaccttta
     2281 ctatagcttg acactgaaca ttgagccttg atgtgtagga taggtgggag gctttgaagt
     2341 gtggacgcca gtctgcatgg agccgacctt gaaataccac cctttaatgt ttgatgttct
     2401 aacgtggacc cgtgatccgg gttgcggaca gtgtctggtg ggtagtttga ctggggcggt
     2461 ctcctcctaa agagtaacgg aggagcacga aggttggcta atcctggtcg gacatcagga
     2521 ggttagtgca atggcataag ccagcttgac tgcgagcgtg acggcgcgag caggtgcgaa
     2581 agcaggtcat agtgatccgg tggttctgaa tggaagggcc atcgctcaac ggataaaagg
     2641 tactccgggg ataacaggct gataccgccc aagagttcat atcgacggcg gtgtttggca
     2701 cctcgatgtc ggctcatcac atcctggggc tgaagtaggt cccaagggta tggctgttcg
     2761 ccatttaaag tggtacgcga gctgggttta gaacgtcgtg agacagttcg gtccctatct
     2821 gccgtgggcg ctggagaact gaggggggct gctcctagta cgagaggacc ggagtggacg
     2881 catcactggt gttcgggttg tcatgccaat ggcactgccc ggtagctaaa tgcggaagag
     2941 ataagtgctg aaagcatcta agcacgaaac ttgccccgag atgagttctc cctgagactt
     3001 taggtctcct gaaggaacgt tgaagacgac gacgttgata ggccgggtgt gtaagcgcag
     3061 cgatgcgttg agctaaccgg tactaatgaa ccgtgaggct taaccttaca acgccgaaga
     3121 tgttttggcg gatgagagac gattttcagc actgattccg gattttcggg aacgaaagat
     3181 aaaagattcg tttccggc
//
LOCUS       DAJVKX010000241         3084 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.242, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000241 DAJVKX010000000
VERSION     DAJVKX010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3084
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.242"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            114..1184
                     /gene="rfaQ"
                     /locus_tag="OPY25_004452"
     CDS             114..1184
                     /gene="rfaQ"
                     /locus_tag="OPY25_004452"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HCS0929883.1"
                     /translation="MEKPFRRILIIKMRFHGDMLLTTPVISTLKQNYPDAKIDVLLYQ
                     NTIPILSENPEINALYGISNKGAGTKEKIKNALSLIKKLRANSYDLVVNLTDQWSVAL
                     IVRFLNAKIKISQDFGNRQSALWKKSFTHLVPYAGEHAVERTLSALKPLALKQYVTET
                     TMSYRPEHWENMRQQLKQLGVTRQYVVIQPTARQLFKCWDNDKFSQVIDAVQRRGYQV
                     VLTSGPAADEMACVDAIACGCETKPVTGLAGKTRFPELGALIDHADLFIGVDSAPGHI
                     AAAVKTPVICLFGATDHVFWRPWTDDIIQFWAGNYQPMPERHELDRNKKYLSVIPAED
                     VIAATEKMLPHEARPIDLDSLL"
     gene            1181..2305
                     /locus_tag="OPY25_004453"
     CDS             1181..2305
                     /locus_tag="OPY25_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCS0929884.1"
                     /translation="MRVAFCLYKYFPFGGLQRDFMHIAQTVAARGHQVRVYTQSWEGE
                     CPDNFELIRVPVKSRTNHGRNAEYYAWVQHHLRDHPVDRVVGFNKMPGLDVYYAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEHGKQTQLLMLTNKQIADFQKHYQTEAE
                     RFHILPPGIYPDRKYSQQIPNSRQIYRQKNGISEQQKLLLQVGSDFTRKGVDRSIEAL
                     ASLPESLRQNTVLCVVGQDKPKKFAALAERSGVGTNVHFFSGRNDIAELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAMTEPFRQDALNEVLLRA
                     LTQPSLRSAWAENARYYADTQDLYSLPEKAADIITGDLDG"
     gene            2298..>3084
                     /gene="rfaP"
                     /locus_tag="OPY25_004454"
     CDS             2298..>3084
                     /gene="rfaP"
                     /locus_tag="OPY25_004454"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HCS0929885.1"
                     /translation="MVELKAPLTTLWRGKDAFEEVKTLQGEVFRELEMRRTLRFELDG
                     KSYFLKWHKGTSLKEIVKNLISLRMPVLGADREWHAIHRLHELGVDTMHGVGFGEKGV
                     NPLTRTSFIITEDLTPTISLEDYCVDWAVNPPDAQVKWMIIKRVATMVRKMHAGGINH
                     RDCYICHFLLHLPFTGREEDLKISVIDLHRAQIRQHVPLRWRDKDLIGLYFSSMNIGL
                     TQRDIFRFMREYFSLPLREILQKDSGLIHQADVKAARIKERTIR"
BASE COUNT          813 a          684 c          777 g          810 t
ORIGIN      
        1 ctagcgcatc taaaatgagt gcggtattag ccatcgggtt gctgtgaagc ctggggcggt
       61 agcgtgcttt tttctgctta tttatccgga caatttcaac caaagagtcg cttgtggaaa
      121 agccatttcg aagaattctg attataaaaa tgcgttttca tggagacatg ttacttacca
      181 ctcctgtcat cagcacgctg aagcagaatt atcccgatgc aaaaatcgat gtgcttcttt
      241 accagaacac cataccgata ttgtcggaaa atccggagat taatgcactc tacggcatca
      301 gtaacaaagg cgcaggaaca aaagagaaga tcaaaaacgc gctatcgtta atcaaaaaat
      361 tgcgtgctaa ctcgtatgat ctggtcgtca atctcaccga tcagtggagc gtggcgctta
      421 ttgtgcgttt tttaaacgca aaaataaaaa tctcgcaaga tttcggtaat cgtcagtctg
      481 ctttatggaa aaaaagcttt acacatttag taccttatgc gggagaacat gctgttgagc
      541 gcacattatc cgcgctaaag ccgttagcgc taaaacagta tgtcacggaa accaccatga
      601 gctatcgccc ggaacattgg gaaaacatgc gacaacagct caaacaactt ggtgtgaccc
      661 gacaatatgt tgttattcag cctacggcac ggcagctatt taagtgctgg gataatgata
      721 aattctcgca ggttattgat gccgtgcagc gccgcggtta tcaagttgta ctgacgtcag
      781 gcccggccgc agacgagatg gcctgcgtgg atgctattgc atgcggctgt gagacaaaac
      841 cggttactgg tctggcgggt aaaactcgct ttcctgaatt gggcgcattg attgaccatg
      901 cggatctctt tatcggcgtt gattcggccc ccggtcatat tgccgcagca gtcaaaacgc
      961 cggtcatttg tctttttggc gcgacggatc atgtattctg gcgtccctgg accgacgaca
     1021 tcattcagtt ttgggcagga aattatcagc cgatgcctga acggcatgag cttgatcgta
     1081 ataaaaaata cctttccgtg attccggctg aagatgttat cgccgcgacg gaaaaaatgc
     1141 tgccgcatga ggcacgcccc atagatttgg acagcctgct atgagagttg ccttttgctt
     1201 atataaatat tttccttttg gcggtctgca gcgtgatttt atgcatattg ctcaaaccgt
     1261 ggcggcgcga ggtcatcagg ttcgtgttta tactcagtca tgggaagggg aatgcccgga
     1321 taactttgaa ttaatccgcg tgccggttaa atcccggacg aaccacggtc gtaacgcaga
     1381 atattatgcc tgggtgcaac accatttgcg cgaccatcct gtcgatcggg tggttgggtt
     1441 caataagatg ccaggccttg atgtgtatta cgccgcagac gtgtgttacg ccgaaaaagt
     1501 cgcacaggaa aaaggatttt tctatcgcct gacatcacgc tatcggcatt atgctgcttt
     1561 tgaacgcgcc acgtttgaac acggcaagca gacgcaacta ttaatgctga cgaataagca
     1621 gattgctgac ttccaaaaac attatcagac tgaagcggag cgttttcata ttcttcctcc
     1681 ggggatttac ccggatagaa aatatagcca acagatcccg aacagtcgtc aaatttatcg
     1741 tcagaaaaat ggtatctcag aacagcaaaa attactgttg caagtagggt ctgactttac
     1801 ccgtaaaggt gtggatcgct ctattgaagc gctggcatcg ctacccgaat ctttacggca
     1861 aaatacggtg ctctgtgttg tcgggcagga taagccgaag aagtttgcag cactggctga
     1921 aagaagcggc gtcggcacga atgtgcattt tttctccgga cgtaatgata ttgcggagtt
     1981 aatggcggca gccgaccttt tactgcatcc agcctatcag gaagctgctg gtattgtttt
     2041 gctggaagcc attactgctg gtttgccggt gttgacaacc gcggtgtgcg gttatgcaca
     2101 ttatattgtg gatgcaaact gtggcgaagc gatgacggaa cctttccgcc aggatgcgct
     2161 aaatgaggtt ttactcagag cgctgacaca gccttcctta cgcagcgcct gggctgaaaa
     2221 tgcgcggtat tatgctgata cccaggattt atacagctta ccggagaagg ccgcagatat
     2281 tatcacaggt gatttagatg gttgagctga aagcgccgtt aaccacacta tggcgcggta
     2341 aagatgcttt tgaggaagtg aaaacgttac agggcgaagt gttcagagaa ctggagatgc
     2401 gtcgaacatt gcggtttgag ctggacggca aaagctactt cctgaagtgg cataaaggca
     2461 cttcgctgaa agaaattgtg aagaacctga tttcgttacg tatgcctgtt ctgggcgctg
     2521 acagagaatg gcacgccatt catcgtctac atgagctggg cgttgatacg atgcacggcg
     2581 ttggttttgg tgaaaaaggc gtaaacccgc taaccagaac atcatttatt atcaccgaag
     2641 atttaacgcc taccattagc cttgaagact actgtgttga ctgggctgtt aatccaccgg
     2701 acgcgcaggt gaagtggatg attattaagc gtgttgcgac tatggtacgt aaaatgcacg
     2761 ccgggggaat taaccatcgc gactgttata tttgccactt tcttctgcat ttacctttca
     2821 ctggtcgcga agaggattta aaaatctccg taatcgacct gcatcgcgcg cagatacgtc
     2881 agcacgttcc ccttcgctgg cgtgacaaag atttaattgg gctttatttt tcttcaatga
     2941 atattggcct gactcagcga gatatattcc ggtttatgcg tgagtatttc tcactccccc
     3001 tgcgagagat tttgcaaaaa gactcggggt tgattcatca ggcggatgtt aaagccgctc
     3061 gaattaaaga aagaacaata agaa
//
LOCUS       DAJVKX010000242         2993 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.243, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000242 DAJVKX010000000
VERSION     DAJVKX010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.243"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..458)
                     /locus_tag="OPY25_004455"
     CDS             complement(<1..458)
                     /locus_tag="OPY25_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HCS0929886.1"
                     /translation="MLLITDLDGTLLTSQKTISPRTRQALIAFRQDGSLLAACSARPV
                     SSMVRLLHQQQVDRLFSWCAGFNCGHLLEMAGQRIIHAAPLSATDLWNIDQHISLSRY
                     HHHFFSAEAIHHRDDRLIAPWTTYEARLFGLPLITETTENIFNRRDIYKIT"
     gene            complement(475..1314)
                     /locus_tag="OPY25_004456"
     CDS             complement(475..1314)
                     /locus_tag="OPY25_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine biosynthesis protein"
                     /protein_id="HCS0929887.1"
                     /translation="MFKGDMNKKRAKALQKVKEAITLHGGQTILSTGITGDDARLAKA
                     VCEAGVKLLEPNHPALALARGHKGVSNMHAAEQIRHEITNSQMAEAVHGVRNVVPDDI
                     FITVGIAGGFTETLPVPLSETEILEIARAGADGLHTHKSDWDDLQDIVNLAHQYGLTV
                     DAYIGHPDDLHTFGIPARTPEEVASVAKRMQDIGVDMIGLMTGMSYEGVAAGDIPQMI
                     KDRLRALVGAVDVPTLAEGGINLANAKAFKDTGVNILVVGTAIDNMVCNAAKEAVTPF
                     IVH"
     gene            complement(1338..2918)
                     /locus_tag="OPY25_004457"
     CDS             complement(1338..2918)
                     /locus_tag="OPY25_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000716843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter"
                     /protein_id="HCS0929888.1"
                     /translation="MAIIGSSGGNLYNLGGAEPEKLLQEIYQQCEAAGVNVAAVQFIA
                     AEASMDVAKPDTPASVYALTTENQQKPQRIFQGKLSEVNTSVVESDRQIAEMIRRGEI
                     DGIVVMSADPVKANQAVFAAAVEMKTPIVGTGGTSMALVAAKGANVVATSGTTGTTSR
                     TRAVSFVASLCKHWGIKYKPQLGSASPSQSGSGKSLLKRFNIRSIMIPALPGFIAMAI
                     VLALSHIPGLEKLNDIFEILLKGLPVLVAVLAAKQISELDEVSIVAGVVAGVLSVEGG
                     LIGGIIGGVMAGIFVRWLFELCLNWRFPMTTVNIVAGGISGLAAGLIMHYLLSPLALS
                     AGNYIKLAIESTLAFSPILAGLLAGLVIWPAILGGVYHAVILPLVLLEMEKSGVSFLG
                     AVDMVGLVMVAAGINLANVIAPREKSEAAVATPGLLINLGFGTFVESAYPFMFANKIV
                     FGSAIFWAGMGGMMLGFFNVKGVAYVPAFASPFLSSNALQMAIVMIATMAMTCLTTII
                     ANRFKPVVQSESTTTAVN"
BASE COUNT          703 a          820 c          776 g          694 t
ORIGIN      
        1 gtaattttat atatatcgcg acgattaaag atattttctg tagtttcagt tataagcggc
       61 aacccaaata agcgggcttc atatgttgtc cagggcgcaa tcagtctatc gtcacgatgg
      121 tgaattgctt cggcgctaaa aaaatggtgg tgatagcggg aaagagaaat atgctggtca
      181 atattccaca gatctgtggc ggacaacgga gcagcatgaa taatgcgctg ccccgccatc
      241 tccagaagat gtccgcagtt aaaaccggcg caccagctaa acaacctatc aacctgttgt
      301 tggtgtagca ggcgtaccat tgaggagacc ggtctggcgg aacatgccgc cagcagacta
      361 ccgtcctggc ggaacgcaat cagcgcctga cgcgtgcgcg ggctgattgt tttctgcgag
      421 gtgagtaatg ttccatccag atcggtgatt aacaacatct ctcgttccct gatatcaatg
      481 aacaataaac ggcgtaacgg cttctttggc ggcgttgcac accatgttgt cgatagccgt
      541 accgaccacc agaatattga ctccggtatc tttaaacgct ttcgcgttgg cgaggttaat
      601 cccgccttcc gccagcgtcg gaacatccac cgcgccgacc aacgcccgca ggcgatcttt
      661 aatcatctgc gggatatcgc ctgccgctac gccttcatag ctcatgcctg tcatcagacc
      721 aatcatatcc acgccgatat cctgcatccg cttcgccacg ctggcgacct cttccggcgt
      781 gcgtgcagga ataccgaaag tatgcagatc gtcaggatgg ccaatgtagg catcgacggt
      841 cagaccatat tgatgggcga gattaacgat gtcctgcaga tcgtcccagt cggatttatg
      901 cgtatgtaaa ccgtcggctc cagcgcgggc aatctccaga atttccgttt cgctgagcgg
      961 caccggtaag gtttcggtaa aaccgccggc gataccaacg gtgataaaaa tatcgtccgg
     1021 gaccacatta cgaacaccgt gtacggcctc agccatctgg ctattggtga tttcgtgacg
     1081 aatctgctcc gccgcgtgca tgttgctcac gcctttgtgt ccacgcgcca gcgccaacgc
     1141 agggtggttc ggctccagaa gcttaacgcc agcctcacac acggctttcg ccaggcgcgc
     1201 atcgtcgcca gttattcctg tgctgaggat agtttgccca ccgtgaagcg tgatggcttc
     1261 tttcactttc tgtaacgctt tggcgcgttt tttattcata tcgcctttaa acatggtgta
     1321 cctctggtgt tggtgcatta attaacggct gtcgttgttg attcgctctg tacgacaggt
     1381 ttgaaacggt tagcaataat ggtggtaagg caggtcatcg ccattgtggc aatcattacg
     1441 atggccatct ggagcgcatt gctggataag aacggtgagg cgaaagccgg aacataggcc
     1501 acgcctttga cgttaaaaaa gcccagcatc atgccgccca ttccggccca aaaaatggcg
     1561 gagccaaaaa caattttgtt ggcgaacatg aagggatagg cggattcaac aaaggtgcca
     1621 aaacccaggt taatgagcag gcccggcgta gcaacggcag cttcgctttt ttcacgcggg
     1681 gcgatcacat tggcaaggtt aatacctgcg gccaccatca ccagaccgac catatcgacc
     1741 gcgccgagga agctgacgcc ggatttttcc atctccagca gtaccaacgg caggatcacc
     1801 gcgtgataga cgccgccgag aatggcaggc cagataacca gaccagccag cagcccggca
     1861 agaattgggc tgaatgccag cgtgctttcg atagccagtt tgatgtaatt acccgcagat
     1921 agcgccagcg gactcagcag atagtgcatg attaacccag cggcaaggcc cgatatccca
     1981 ccggcgacga tgttgacggt agtcattggg aagcgccagt tcaggcacag ctcgaacagc
     2041 caacggacga aaatccccgc cattacaccg ccgataatgc cgccgatcag tccgccctct
     2101 acggaaagca cgccagcgac gaccccagcc acaattgaaa cttcatccag ttcggaaatc
     2161 tgttttgccg ccagtaccgc gactaacact ggcagacctt ttagtaatat ttcaaagata
     2221 tcgttaagtt tttccagtcc tggtatgtgg ctcagggcga gtacaatcgc catggcgata
     2281 aagcctggta gcgcagggat catgatgcta cgaatgttaa aacgtttgag caggcttttt
     2341 ccggaaccgc tctgcgaggg cgaagcgcta cccaactgtg gtttgtactt gataccccaa
     2401 tgtttacata gtgacgccac gaaggagacg gcgcgggtac ggctggtggt gccggttgtt
     2461 ccggaggtcg cgaccacatt cgcccccttt gccgccacca gcgccatgga ggttcccccg
     2521 gtgccgacaa tcggtgtttt catctcaacg gcggcggcaa aaacggcttg gttcgccttt
     2581 accggatcgg cgctcattac cacgatccca tcgatctcac cgcggcggat catctcagcg
     2641 atttggcgat cgctttctac taccgaggtg tttacctccg aaagcttacc ctgaaatatg
     2701 cgctgtggtt tttgttggtt ttctgtggtt aatgcataaa ccgatgccgg ggtgtccggt
     2761 ttggcgacgt ccatcgaggc ctctgccgcg ataaattgta cggcggccac attcacgccc
     2821 gcagcctcac actgctgata aatctcctgg agtaacttct ctggctcggc gccacccagg
     2881 ttgtagaggt tgcctccact gcttccaata atcgcaattt tttcatagcg gcctcaaata
     2941 gggtaagggg gttatctgtg ttgtagtgca atcataattc caactaaaac aaa
//
LOCUS       DAJVKX010000243         2841 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.244, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000243 DAJVKX010000000
VERSION     DAJVKX010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2841
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.244"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(240..380)
                     /locus_tag="OPY25_004458"
     CDS             complement(240..380)
                     /locus_tag="OPY25_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929889.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPLDPTVSKTAVILTILT
                     AT"
     gene            476..1192
                     /gene="arcA"
                     /locus_tag="OPY25_004459"
     CDS             476..1192
                     /gene="arcA"
                     /locus_tag="OPY25_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HCS0929890.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLQD"
     gene            1459..1768
                     /locus_tag="OPY25_004460"
                     /pseudo
     CDS             1459..1768
                     /locus_tag="OPY25_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463453.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2152..2823
                     /locus_tag="OPY25_004461"
     CDS             2152..2823
                     /locus_tag="OPY25_004461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0929891.1"
                     /translation="MKQLNGGNVYRPTGKEKNLQAILNIHRHVIQNISPVTITAGKTL
                     DIKIDNQSHILLITKGAIKVCRRIDSIVMGCGVSPMILGLVDAYADLYQLEENSDVFF
                     IAETTCEYYPVPVKDFVEIADEKHLWRDISNILMYRIAFMSNRDRNLIGQDAYSQIKA
                     LLLELWSYPESSRFEINAQNFIQQRTGLSRSRIMQVLSELKAGNYIKILHGRLLELRN
                     LPVSF"
BASE COUNT          772 a          644 c          636 g          789 t
ORIGIN      
        1 ttaacagaac atcgttatcc tgctgtttat ttaggataat ttaatttaaa atagatcctg
       61 ttctttggat tcatcgcatt tattagttgg cttacgtaac tagttggaat attgcaaatt
      121 tgtgatgaaa gctagcattt agctacgatg atttcatcaa actgttaacg tgctacaatt
      181 gaacttgata tatgtcaacg aagcgtagtt ttattaggtg tccggtacgt cttagcctgt
      241 tatgttgctg ttaaaatggt taggatgaca gccgtttttg acactgtcgg gtccagaggg
      301 aaagtaccca cgaccaagct aatgatgttg ttgacgttga tggaaagtgc atcaagaacg
      361 caattacgta ctttagtcat gttacgccga tcatgttaat ttgcgacatg catcaggcag
      421 gtcagggact tttgtacttc ctgtttcgat ttagttggca atttaggtag caaacatgca
      481 gaccccgcac attcttatcg ttgaagacga gttggtaaca cgcaacacgt tgaaaagtat
      541 tttcgaagcg gaaggctatg atgtattcga agcgacagat ggcgcggaaa tgcatcagat
      601 cctctctgaa tatgacatca acctggtgat catggatatc aatctgccag ggaaaaacgg
      661 tctcctgtta gcgcgtgaac tgcgtgagca ggctaatgtt gcgctgatgt tcctgacggg
      721 ccgcgataac gaagtcgaca aaattctcgg cctcgaaatc ggcgcggatg attacatcac
      781 caaaccgttt aatccacgcg aattgaccat ccgtgcccgt aacctgctgt cccgtaccat
      841 gaacctgggt accgtcagcg aagagcgtcg tagcgttgaa agctataagt tcaacggttg
      901 ggaactggat atcaacagcc gttcactgat cggcccggac ggcgagcagt ataaactacc
      961 gcgcagcgag ttccgcgcga tgctgcactt ctgcgaaaac cctggcaaaa ttcagtctcg
     1021 tgccgagctg ctgaaaaaaa tgaccggacg cgagctgaag ccgcatgacc gtactgttga
     1081 cgtcaccatt cgtcgtattc gtaagcattt cgaatccacg ccggatacgc cggaaatcat
     1141 cgccaccatt cacggcgaag gttatcgctt ctgcggcgac ctgcaggatt aattcggccc
     1201 aggcgccaaa ccgtaaaaac agccggtaag ttattcttac tggctgtttc ttatgctccc
     1261 cttccgctaa gcggccccgc tttccctcct gacctgccgt tatgacgtac tcttttacat
     1321 aaaaattgtc gtatagcgct gtttatctca gcttgcgaaa gttaaggtag tttgtgtatt
     1381 tacattaaag agtaatacac gggatttgtt ggtccccaaa aattaagggg atgctcacag
     1441 gacgtgaggt ttcacaggat gaaaaaatca ccattatgct gctacctgtt ttgtgcagcg
     1501 atgtcagctt catcagccgc gctggctgct accgcgccgg tctccgcagg cgttattcat
     1561 ttcaaaggcc agattgtcga atatggttgt aatcttgcgc ctcacgatcg caatatcgag
     1621 gtatcatgtt tgcggaatcc cccatttgca gacagtcgcc acaccgtctg gaaacgctat
     1681 ttcgttgatg aatggaatcg ccacggtacg gcacgtgtcg ttaaaagatc atccggagat
     1741 tcaaagcctg atcgtccagt accgctaacc gcttatggct cccgacggga ggagttccgg
     1801 caggcggcga tttcgctcag taaaacgccg cccgcttgca ttttgtactt ttctctcatt
     1861 cgtatcctcc aacagcgatg ttcatcgctt cgctatcctg tacgctctac gcgctcgtta
     1921 agcacggtac ctatgatagc tgtcataaaa tgattgcaaa taaaatcatc acatttacta
     1981 tggttaacct taaaaacagc gttgtcgctc atgcattgat aaggtgaata cattgactta
     2041 aatattcttg ttggctattt taatttactt aattataatt taagtgaata ttaaatttat
     2101 gtttaccttt taatagtcaa ccactttatc agccataata atggggaaga tatgaagcag
     2161 ttaaacggcg ggaatgtgta tcgtcccaca gggaaagaaa aaaacctgca agccatttta
     2221 aatattcatc ggcacgttat tcaaaacatc tcccctgtca ctattacggc cggtaaaacc
     2281 ctggatatca agattgataa tcaatcccac atcctgttaa tcactaaagg cgctattaaa
     2341 gtatgtcggc gtatcgacag tattgtaatg ggctgtggtg tctcgccaat gattttaggc
     2401 cttgtagatg cctatgccga cttataccag ttagaagaga attcagacgt cttttttatc
     2461 gccgaaacca cctgtgaata ttatcctgtc ccagtaaaag attttgtgga aatagccgat
     2521 gaaaagcatc tctggcgtga catttcgaac atcctgatgt accgcattgc tttcatgagt
     2581 aaccgtgaca gaaaccttat cgggcaggac gcctatagcc agataaaagc gctgttactt
     2641 gaactgtggt cgtatcctga aagctcacga tttgagatca acgcacagaa cttcatacag
     2701 cagagaaccg ggctttcacg cagccgtatc atgcaggtac tttcagaatt aaaagcgggg
     2761 aactatataa aaatactgca tggaagactg ttagagcttc gaaacctgcc ggtttcattt
     2821 taaatgaaca agcgtcgtat a
//
LOCUS       DAJVKX010000244         2749 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.245, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000244 DAJVKX010000000
VERSION     DAJVKX010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2749
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.245"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            132..395
                     /gene="pagD"
                     /locus_tag="OPY25_004462"
     CDS             132..395
                     /gene="pagD"
                     /locus_tag="OPY25_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence protein PagD"
                     /protein_id="HCS0929892.1"
                     /translation="MKHHAFMLWSLLIFSFHVLASSDHCSGLQQASWEIFIYDFGSKT
                     PQPPTNTDKKQARQISSPSCPTAKPMMSAPTNDARKGNTFSRT"
     gene            527..739
                     /gene="cspF"
                     /locus_tag="OPY25_004463"
     CDS             527..739
                     /gene="cspF"
                     /locus_tag="OPY25_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspF"
                     /protein_id="HCS0929893.1"
                     /translation="MSRKMTGIVKTFDCKSGKGLITPSDGRKDVQVHISACRQHETEA
                     LIPGIRVEFCRINGLRGPTAANVYLS"
     gene            1157..1678
                     /locus_tag="OPY25_004464"
     CDS             1157..1678
                     /locus_tag="OPY25_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="HCS0929894.1"
                     /translation="MTLLSGKNTLVLCLSSILCGCTTNGLPAPYSINLSFPVITQNQI
                     NSGGYYINDAEQIRTTDGLCLDTGPDQQNRLTLRECKHVQSQLFSFHRDRITQGEKCL
                     DAAGQGTKEGTPIILYSCTGNDNQRWLTDDNKIKGKQSRKCLGTNSIIVRKGDPVVLA
                     DCDFSRALEFTIR"
     gene            1869..2108
                     /gene="msgA"
                     /locus_tag="OPY25_004465"
     CDS             1869..2108
                     /gene="msgA"
                     /locus_tag="OPY25_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence protein MsgA"
                     /protein_id="HCS0929895.1"
                     /translation="MFVELVYDKRNVEGLPGAREIILNELTKRVHQLFPDAQVKVKPM
                     QANALNSDCTKTEKERLHRMLEEMFEEADMWLVAE"
BASE COUNT          790 a          608 c          566 g          785 t
ORIGIN      
        1 aaaaagtcta ttttgctata aaacccatta ttattaagac tggttaactc ttcgttgaat
       61 aaaaaatgcc aatgacgtcc cataattaat tagatgaact tcgcaagtca ttacatataa
      121 caggaggtgc tatgaaacat catgctttta tgctttggtc attacttatt ttttcattcc
      181 atgttttggc cagttcagac cattgttctg gtttacaaca ggcatcatgg gaaattttta
      241 tctacgattt tggtagtaaa accccgcaac cacctacaaa taccgataaa aagcaagcca
      301 ggcagattag ttcaccatcc tgcccgacgg caaaacccat gatgtccgca ccaaccaacg
      361 acgccaggaa agggaatact ttctccagaa cataatgtta tttatctaca atggtgccga
      421 acgactactt ttagccatcc ggaaatcttg attgccatca aatatagctg gcattatttt
      481 tcctgacgtg tatagtgcgc ctcgttatcc ccattaagga atttgtttgt ctcgtaaaat
      541 gacaggaatt gtcaaaacct ttgattgtaa gagcggtaaa ggtctcatca ccccctccga
      601 tggacgcaaa gatgttcagg tccacatttc agcatgtcgc caacacgaaa cagaagctct
      661 tatccccggt atacgcgttg agttttgtcg tattaatgga ctccgcggac ctaccgccgc
      721 caacgtttat ctttcataat tcgtcacccg gcattttttc agaaaaattt agcgagtacg
      781 tatacctccg cagtctgcta tgaggctttg cctgaaaggc tgcagaatgt tttcagtggc
      841 gaaaatctaa aagatttatt ttgctaatga ctcctgtgac ctcttttatc atatatcggg
      901 tgtcaacccc ccttctcact ttgtttaacg tgaagaaatg tacagccgtt tttcactgtg
      961 atagcatgta atattgcaaa agtatttaac gctatatacc catcgtcgca ggagtggctg
     1021 gctgcgcgca tttaaccgaa gtatttatgt gattctatcg gaattatctt tattgccgct
     1081 caatgctacg tcatattcag tgggtataaa ttgccaatat agttgtaatg ctatttattt
     1141 ttagggtaat aattgaatga ctttgctttc aggaaaaaac acactggttc tctgcctctc
     1201 ctctatttta tgtggatgta cgacgaacgg cttacccgca ccttatagta ttaatttgtc
     1261 gttcccggtc attacacaaa accaaattaa ttccggtggt tattacataa atgacgcgga
     1321 acaaattcgg acaactgatg gtctgtgcct tgatacaggc ccagatcaac agaatcgttt
     1381 gacgctgcgg gagtgtaaac atgtgcaatc tcagcttttc tcatttcacc gagacagaat
     1441 cacgcagggt gagaaatgtc tggatgctgc aggacagggt acgaaagaag gcacgccaat
     1501 cattctttat tcatgcacgg gtaatgataa ccagcgctgg ctcactgatg ataacaaaat
     1561 taaggggaaa cagagccgaa aatgcctggg cacaaatagc attattgtca gaaaaggcga
     1621 ccctgttgtg ttagccgatt gcgattttag tcgcgccctg gaatttacca tcaggtagca
     1681 ggacaccgct gtgaagagag agccgctaac ctcttgacat gacaacaggt tagcgacctt
     1741 tacttccatg tgcgatcaat ttactttaca tccgcaacgt taggatgaca aaacggcggc
     1801 taaaccttga caccggttat atacccagct taaatactgg tcatccaacc agtaaaaagg
     1861 aaatggcgat gttcgtcgaa ctcgtttatg acaagcgaaa tgttgaaggt ttgccaggcg
     1921 cacgcgaaat catcctcaat gaactcacaa aacgcgtaca tcaacttttt cccgatgcgc
     1981 aagtgaaagt taagccaatg caggcgaacg cattaaacag tgactgtaca aaaaccgaga
     2041 aagaacggct gcaccgtatg ctggaagaga tgtttgaaga ggctgatatg tggctggtcg
     2101 ccgaataacg tcccctcctg cgaaagcgac atgtccgatc gaaaacagcg ccctgaggcg
     2161 ctgtctgtga cgatataacg caaacgccac cactcagaac atgtagcgga agttggcgtt
     2221 tatagcgtgg tcaacatgct atttgccaaa tgccgccagc tccagtcatt gtcactgaac
     2281 gttttgccca gtgccacacc tgtacgccct atcaacggat tatacgtttt gttgcgcatc
     2341 gacgctattg gtcacggttt tacagtaaaa acggtacctg ttctcagact cttccggcgt
     2401 cagtgcaccg ttataatgat gaggtctgac gctattgtag ccgttcaaga tgtaaccatt
     2461 gatttgtttg gttttcttgt tcactaagtt acctgttttg tgttgaggtg agaacatcgc
     2521 ctttaatcag gtggccaaat ttactatgtc actacaagag tgagaataga tgaaatgtca
     2581 cctccctcac agggatataa taatcctggt aatgaaaaat ttatgtttac ttataaagta
     2641 ccaatgatat cgaatctctc tttccgcaaa taaatcaacc caatacagtt acaatgagtt
     2701 aagcgaatgg agttttaaat tcagttagtt gtttattcat agttgtctc
//
LOCUS       DAJVKX010000245         2741 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.246, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000245 DAJVKX010000000
VERSION     DAJVKX010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2741
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.246"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            9..761
                     /gene="gpmA"
                     /locus_tag="OPY25_004466"
     CDS             9..761
                     /gene="gpmA"
                     /locus_tag="OPY25_004466"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCS0929896.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGFSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNDTILPRMKSGERVIIAAHGNSLRALVKYLDNMSEDEILELNIPTGVPLVYEF
                     DENFKPIKHYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(852..1628)
                     /locus_tag="OPY25_004467"
     CDS             complement(852..1628)
                     /locus_tag="OPY25_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCS0929897.1"
                     /translation="MRRLMLRSFSAGYSTQPVIADLNVPLLPRGKITILLGPNGCGKS
                     TLLRSLAGLNNVDGEALLDGEDLMSLSFAERAQKVVFLPQSLPQGVHLHVLESIIVVL
                     RASGGRDNAQGRAQILAILEQLGITHLALQYLDQLSGGQRQLVGLAQSLIRRPELLLL
                     DEPLSALDLNYQFHVMDLVRRDTQAQNRVTIVVAHDINIALRHGDHVLMLKDGRLVAS
                     GAPETVITAERLAEVYRVRGRVERCSQGKLQVVLDGVIAV"
     gene            complement(1628..2707)
                     /locus_tag="OPY25_004468"
     CDS             complement(1628..2707)
                     /locus_tag="OPY25_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCS0929898.1"
                     /translation="MTCQDKSLLAPGLASTPVIPRYRQIIRKRAVLMSAIALAMMVSL
                     MVDVTCGSSGLPLSALWQALFQPEKVNAGIHVIVWDIRLPYALMALLVGMALGLAGAE
                     MQTILNNPLATPFTLGVSSAAAFGAALAIVLGIGIPGIPAAWFIPANAFIFALLSALL
                     LDGITRWTGVAASGVVLFGIALVFTFNALVAIMQFVADEDTLQGLVFWTMGSLVRASW
                     EKLGVLAVVFIAVLFCALRSAWQLTALRLGEERAMSFGVHVRRLRLLSLLRISLLSAL
                     AVAFVGPIGFIGLVAPHIARILLGEDHRFYLPGSVLIGGLVLSLASIAAKNSIPGVMV
                     PVGIVTSLVGVPFFLSIVLRHRGSL"
BASE COUNT          739 a          784 c          713 g          505 t
ORIGIN      
        1 gtgagagtat ggctgtaact aagctggttc tggtacgtca cggtgaaagt caatggaaca
       61 aagagaaccg tttcaccggc tggtatgatg ttgacctgtc tgaaaaaggc gtaagcgaag
      121 caaaagcagc gggtaaactg ctaaaagaag aaggtttcag ctttgatttt gcctacactt
      181 ccgtactgaa acgcgctatc catacgctgt ggaacgtact ggatgaactg gatcaggcgt
      241 ggctgccggt ggaaaaatcc tggaaactca atgaacgtca ctatggcgcg ttgcaagggc
      301 tgaataaagc ggaaacggca gaaaaatatg gtgacgagca ggttaagcag tggcgccgcg
      361 gttttgccgt gacgccgccg gaactgacca aagatgatga gcgttatccg ggtcacgatc
      421 cacgttatgc caaactgagc gagaaagagc tgccgttgac cgaaagtctg gcgctgacca
      481 tcgaccgcgt tattccttac tggaacgaca ccatcctgcc gcgtatgaag agcggtgagc
      541 gcgtgatcat cgccgctcac ggtaactcat tgcgtgcgct ggtgaaatac ctggataaca
      601 tgagtgaaga tgagattctt gagttaaaca tcccgaccgg cgtgccgctg gtgtatgagt
      661 tcgacgaaaa cttcaagccg atcaaacatt actatctggg taacgctgac gaaatcgccg
      721 cgaaagcggc tgccgtggcg aatcagggta aagcgaagta atcacctttg ccggatggcg
      781 gtataactgc cttatccggc ctacgagcaa tgggtaggcc ggataagcgc agcgccatca
      841 ggcaatatgt cttaaacagc gatcacgccg tccagcacca cctgcaattt cccctgcgaa
      901 cagcgctcca cgcgtcctcg tacccggtac acttcagcca gacgctccgc agtaatcacc
      961 gtctccggcg cgccgctggc gaccagcctg ccgtctttta gcatcaggac atggtcacca
     1021 tgacgcaggg caatattaat gtcatgcgcc acgactatcg tcaccctatt ttgcgcctgg
     1081 gtatcccgac gcacgagatc cattacgtga aactgatagt ttaaatccag cgcgctgagc
     1141 ggctcatcca gcaacagaag ttcagggcga cgaatcagcg attgcgccag acccactaac
     1201 tgccgctgac cgccggaaag ctggtcgaga tactgcaacg ccagatgcgt tatgcccaat
     1261 tgctcaagga tagccagtat ctgcgctctg ccctgcgcat tgtctctgcc gcctgatgcc
     1321 cgcagtacca cgataatcga ctccagtaca tgcagatgta cgccctgcgg taatgactgc
     1381 ggcaaaaaca caactttctg cgcccgctcg gcaaacgata acgacatgag atcttcgcca
     1441 tcaagcagcg cctcgccgtc gacgttattc agcccggcca gcgaacgtag taacgtcgat
     1501 ttaccacagc cgttcggccc cagcaaaatg gtaattttcc cgcgcggcag taagggaacg
     1561 ttgagatctg caataaccgg ctgagtggaa tagccggcgc taaatgagcg gagcattaac
     1621 ctgcgcatca gagactcccc cgatgtcgca atacaatgct taaaaagaac ggaaccccga
     1681 ccagcgaggt gacaatcccc accggcacca tgacgcccgg aatactattt ttcgccgcaa
     1741 tagaggccag cgataacacc agcccgccta tcagcacgct gcccggaagg tagaaacggt
     1801 gatcttcccc caacagtatt cgcgcaatgt gcggcgcaac gagaccaata aaaccaatcg
     1861 gcccgacgaa agctaccgcc agcgctgata acaagctgat acgcaacaat gacagcaggc
     1921 gtaaacggcg gacatgaacc ccaaagctca tcgccctctc ttcgcccaga cgtaatgccg
     1981 tgagttgcca ggcgcttcgt aacgcgcaaa aaagcacagc aataaacacc acggccagta
     2041 cgcccaattt ttcccacgac gcgcggacca ggctccccat cgtccagaat accagcccct
     2101 gcagcgtatc ttcatcagcc acaaactgca taatggcgac caacgcgtta aaggtgaata
     2161 ccagcgcaat accgaacaac accactccgg atgcggcgac gcctgtccaa cgggtaatac
     2221 cgtccaggag taacgcggat aaaagcgcaa agatgaacgc attggccggg ataaaccagg
     2281 cggcaggaat accgggaata ccgatcccca acacaatcgc cagcgcagcg ccaaaagccg
     2341 ccgcggacga tacgccaagg gtaaacggcg tcgccagcgg attatttaaa atggtttgca
     2401 tttcggcgcc cgctaaccct aacgccatgc ccaccagtag ggccatcagg gcatagggta
     2461 agcggatatc ccagacaata acgtgtatgc ccgcattcac cttttccggc tggaaaagcg
     2521 cctgccacag cgcactgagc ggtaaaccag aagacccaca ggttacatcc accatcagtg
     2581 aaaccatcat cgccagcgca atagctgaca tgagcacggc ccgtttgcgt atgatctggc
     2641 gatagcgcgg aatgacgggc gtggaagcga gaccgggggc taaaagtgat ttgtcctgac
     2701 aggtcatggt tcgagcgacg ttattaatca gaagagaatt a
//
LOCUS       DAJVKX010000246         2723 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.247, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000246 DAJVKX010000000
VERSION     DAJVKX010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2723
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.247"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..720
                     /gene="sopE"
                     /locus_tag="OPY25_004469"
     CDS             <1..720
                     /gene="sopE"
                     /locus_tag="OPY25_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system guanine
                     nucleotide exchange factor SopE"
                     /protein_id="HCS0929899.1"
                     /translation="TKITLSPQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIEL
                     RSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKD
                     PAYASQTREAILSAVYSKNKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDV
                     FTPSGAGANPFITPLISSANSKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMP
                     TPQQFQLILENIANKYIQYTP"
     gene            complement(918..1325)
                     /locus_tag="OPY25_004470"
     CDS             complement(918..1325)
                     /locus_tag="OPY25_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCS0929900.1"
                     /translation="MSEYYYSFKEKGFFWQPDTESDNYPDDLIPLTDEYYRELMQGQV
                     DGKYIEHRKGGPVLVEHREYTPEELVAQAEARKAELLAEAESVIAPLARAVKLKIATD
                     EEIKRLEAWELYSVMVNRVDTANPDWPEKPAQI"
     gene            complement(1332..>2723)
                     /locus_tag="OPY25_004471"
     CDS             complement(1332..>2723)
                     /locus_tag="OPY25_004471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0929901.1"
                     /translation="QVIPETEGGWWIREVGLFDETGALIAVGNCPESYKPQLTEGSGR
                     TQTVRMVLITSSTDNITLKIDPAVVLATRKYVDDKALELKVYVDDLMAKHLAAPDPHS
                     QYAQKDSPTLTGIPKVPTPAAGNSTKQIANTEFVASSIAAMVDSAPAALDTLNELAAA
                     LGNDPNFATTMLNALGGKQPLDNTLTNLSGKDVAGLLAYFGLGETINRAADALQKSQN
                     GADIPDKPRFVQNIGLKETLNPTKRVSIGNIGTGVFDGSTPCINIGDSDSGFIGSADG
                     VLDIYCNGAKVGYINGNGLHMLTDIHFDNASMTTNGDIFSSVWGDNWLSIWITNQLNT
                     RGTIDWINSELAIRDNNINTRATIDYVNQTFARKNTGSIQDWGWILDDSTGFIMQWGT
                     LGNSNGTYNFPRAFPVGCFAVFVTNTNAQGTQVDNAFGYPVSNSQFFAATKSSGMANL
                     VNNFPVAWFAIGR"
BASE COUNT          734 a          689 c          562 g          738 t
ORIGIN      
        1 acaaaaataa ctttatctcc ccagaatttt agaatccaaa aacaggaaac cacactacta
       61 aaagaaaaat caaccgagaa aaattcttta gcaaaaagta ttctcgcagt aaaaaatcac
      121 ttcatcgaat taaggtcaaa attatcggaa cgttttattt cgcataagaa cactgagtct
      181 tctgcaacac actttcaccg aggaagcgca tctgagggcc gggcagtgtt gacaaataaa
      241 gtcgttaaag attttatgct tcaaacgctc aatgatatag atattagagg tagtgcgagt
      301 aaagaccccg catacgccag ccagacccgt gaagctatac tatcggcagt ttacagcaag
      361 aataaagatc agtgttgtaa tttgctcatc agcaaaggga tcaacatagc gccttttctt
      421 caggaaattg gcgaagcagc gaaaaatgca ggtctgcccg gaacaaccaa aaatgacgtt
      481 tttacgccaa gcggcgcagg ggccaatcct tttataactc cgttgatttc atcagcaaac
      541 agtaagtatc cacgtatgtt tatcaatcaa catcagcagg catcctttaa aatctatgcg
      601 gagaagatca ttatgacaga agttgcacca ctgtttaatg agtgtgctat gccgactcca
      661 cagcaattcc aactgatact agaaaacatt gctaataaat atatacaata cactccctga
      721 acacagaaaa accaaaaaat atgcggagcc tcttcctgat taatatgaac caatagtatc
      781 cataattttc cccaggaact aactccggag ctaaaccgtc atttaccagt gctaaaatta
      841 tacactcaac catcaaaaaa aatagccatt gctgctatat aacatatagc agcagtctct
      901 actacatatc tatattttta tatctgagct ggtttctccg gccagtctgg gttagctgta
      961 tccacccggt ttaccattac gctataaagt tcccatgctt ccagccgttt aatctcttca
     1021 tctgtggcaa ttttcagttt taccgcccgc gccagtggcg caataactga ctctgcctca
     1081 gcaagaagtt ccgcttttct ggcttcagcc tgtgcaacca gctcttcagg cgtatattcg
     1141 cgatgctcaa ccagtaccgg gcctcctttc ctgtgctcga tatattttcc gtccacctgg
     1201 ccctgcatca gctcgcgata atactcatct gtcaggggaa ttaaatcgtc agggtaatta
     1261 tcggattcgg tatccggttg ccagaaaaaa cctttttctt taaagctgta ataatattcg
     1321 ctcattgata tttatctccc aatcgcaaac caggctacag gaaaattatt gaccagattg
     1381 gccattcctg atgacttggt ggcggcaaaa aactgactgt tgctcaccgg gtatccgaat
     1441 gcgttatcca cctgggtgcc ctgagcgttg gtattggtta caaaaacggc aaagcaacca
     1501 acagggaaag cgcgcgggaa attgtaggtt ccgtttgagt taccaagtgt tccccactgc
     1561 attataaatc cggtgctgtc gtccagaatc cagccccagt cctgaatgct gccggtattt
     1621 ttacgggcga aagtctggtt aacataatca atggtggcgc gggtgttgat gttgttgtca
     1681 cgaattgcca gttcactatt gatccagtca atcgttccac gggtatttag ctgattagta
     1741 atccagatac tcagccagtt atccccccac actgaactaa aaatgtcacc attagtggtc
     1801 atgctcgcat tatcgaaatg aatatcagtg agcatgtgta atccgttacc attgatataa
     1861 cccactttgg caccgttaca gtaaatatcc agtacgccat ccgcgctgcc gataaatcca
     1921 ctgtcactgt caccgatatt tatacacggt gtgctgccgt caaaaacgcc ggttccgata
     1981 ttgcctatac tcacgcgttt tgtcgggttc agggtttctt ttaaaccgat attttgtaca
     2041 aaccgcggct tgtcaggaat gtctgcaccg ttctgtgatt tttgtagcgc atcggcggca
     2101 cgatttatcg tttctcctaa accgaagtat gcgagaaggc cggcgacatc ttttccgctt
     2161 aaattcgtca gcgtattgtc cagcggctgc tttccaccaa gagcgtttaa catcgttgtg
     2221 gcaaaattcg ggtcattccc cagagccgct gccagctcgt tcagcgtatc cagtgctgca
     2281 ggcgcagaat ccaccattgc cgcaatagac gatgccacaa attccgtgtt cgcaatctgt
     2341 ttagtgctgt tacccgccgc tggcgtcggt acctttggaa tccctgtgag tgtcgggctg
     2401 tccttctgcg catactgtga atgcgggtcc ggcgcagcaa gatgctttgc catcaggtcg
     2461 tctacatata ccttcagctc cagcgcctta tcatctacat atttacgggt tgccagcact
     2521 actgcagggt caattttcag ggtgatgtta tcggtgctgc tggtaatcag taccatgcgc
     2581 acggtctgcg tacgtccgct cccttctgtc agctgcggct tgtagctctc agggcagtta
     2641 cccacagcga tcagcgcacc ggtttcatca aacaggccaa cttcacgaat ccaccacccg
     2701 ccctcagttt ccgggattac ctg
//
LOCUS       DAJVKX010000247         2714 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.248, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000247 DAJVKX010000000
VERSION     DAJVKX010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2714
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.248"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            474..1403
                     /locus_tag="OPY25_004472"
     CDS             474..1403
                     /locus_tag="OPY25_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK family antimicrobial peptide resistance
                     protein"
                     /protein_id="HCS0929902.1"
                     /translation="MTMQQSDMERYNPLLMLKEVMAQTPYRHKRWGERKFRYKFVLRC
                     LINPVTTIKYFNELCHLSQPRTLIIHRPLLPAKIQRPYLYTGLSIRCRAKAILEHYQF
                     VQSFPESKIKKILLSEEQILLAHLEGKNGALVDIYCGPCGYDREGELTLTLCFNDTPL
                     ARLSFSFIRHEGKQIALVAGLQGPSKHIGPQVIRNATKDCYGLFPKRMLYEAFATLMQ
                     ACNVDEIYAVSENNHVYRQLRYLFQKKKTFVASYSEFWESLNGVKKGALYHLPSQVMR
                     KAPESIPSKKRAEYRKRYHILDTIIQEVNSLSR"
     gene            1697..2593
                     /locus_tag="OPY25_004473"
     CDS             1697..2593
                     /locus_tag="OPY25_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antimicrobial resistance protein Mig-14"
                     /protein_id="HCS0929903.1"
                     /translation="MKIQEVKRILTRWQPSSFTLYREVFTQYGGSINMHPDIVDYFMK
                     RHNWHFKFFHYKEDDKIKGAYFICNDQNIGILTRRTFPLSSDEILIPMAPDLRCFLPD
                     RTNRLSALHQPQIRNAIWKLARKKQNCLVKETFSSKFEKTRRNEYQRFLKKGGSVKSV
                     ADCSSDELTHIFIELFRSRFGNTSSCYPADNLANFFSQLHHLLFGHILYIEGIPCAFD
                     IVLKSESQMNVYFDVSNGAIKNECRPLSPGSILMWLNISRARHYCQERQKKLLFSIGI
                     LKPEWEYKRMWSTPYFTGKSIC"
BASE COUNT          813 a          591 c          533 g          777 t
ORIGIN      
        1 atcattagat ttgcatttag aaataaggtg aataccccct ttgcgtctgg ttacataatc
       61 acgcatcacg acgcgttgct gtctgactta cacaatacca gccaaataaa tatattggct
      121 tatactcgtc atacttcaag ttgcatgtgc tgcggctgcg ttccctcacc ccagtcactt
      181 actttagtaa gctcctgggg attcgctcgc ttgccgcctt cctgcaactc gaattattta
      241 gagtataaac attatttaaa ataataaaca cggcattcgt tttaatacta cgttcaggac
      301 tcatcccact cattagcaga aaatctatta aaaagcgcgt tcaggcgttt tattgctgcc
      361 attgataaac tgtttaacaa cgtcgtctgt acaggccttc ttcgttgcct ttacgtttaa
      421 ctcaatcagg ctaccgtctc ggttataagt ctatcgagta gtagggacgt agtatgacga
      481 tgcagcaaag tgatatggaa agatataatc cattattaat gttaaaagaa gtcatggcgc
      541 agacgcctta tcgccataaa cgctggggag agcgtaagtt tcgctataaa tttgtattac
      601 gttgccttat taaccccgta acgacaatta aatacttcaa tgaattatgc catctgtctc
      661 agcccagaac gctgattatt catcgtccac tgttgccggc aaaaatccag cggccctatt
      721 tgtataccgg acttagcata cgttgccggg caaaggctat tctggaacac taccagttcg
      781 ttcagtcctt tccggaaagt aaaattaaaa agatccttct gtccgaggaa caaatcttac
      841 tcgctcacct ggaaggaaaa aacggtgctc tggtagatat ctactgcggt ccctgtggct
      901 atgacagaga aggtgaactg acattaacgc tgtgcttcaa tgatacgccg ttggcacgtt
      961 tatcattttc ctttatccgc catgaaggga agcaaatagc gctggttgcc gggttacagg
     1021 ggcccagtaa acatatcggc ccacaagtca tacgtaacgc caccaaagat tgttacggtc
     1081 tctttcctaa acggatgctg tatgaagcat ttgcgacatt gatgcaggcc tgtaatgtcg
     1141 acgagattta cgcggtaagt gaaaacaacc atgtttatcg tcaactcagg tacttattcc
     1201 agaagaaaaa aacttttgtg gccagctata gtgaattctg ggagtcgcta aacggcgtta
     1261 agaaaggtgc cttatatcat ctgccatcac aggtgatgcg taaagcgcct gaaagtatcc
     1321 ccagcaaaaa acgcgcagag tatcggaagc gctatcatat tctggataca ataatacaag
     1381 aggttaacag cctctcccgg tagaactatt tcatacgcgg atgtgcagat cctgctaccg
     1441 ttcagcggat ctctttgaaa tctgtatcgc tactggatgg ttaaatacag aatggcttgc
     1501 gagtgaaaag cgcggcatta aaccgtcgct ttcattcatg ctatgatcaa catcttaatc
     1561 ttattccctt caccataacg tcatcgatta gcatgttaac cattaaatac aagctaaaca
     1621 tttgtcacat ttttatttgg ttgagcaaaa aaataataca aaatagaatt ttcagtaagc
     1681 taagtcagga gttttagtga aaatacaaga agttaagcgt atattaaccc gctggcagcc
     1741 gtcttccttt accctatacc gggaggtgtt tacgcaatac ggcggtagta tcaatatgca
     1801 cccagatatt gtggattatt ttatgaagcg ccataactgg cattttaaat tcttccacta
     1861 taaagaagat gataagatta aaggcgccta ctttatctgt aatgatcaga atattggcat
     1921 cctgacgcgc agaaccttcc cgctatcttc agatgagata cttattccga tggcgccaga
     1981 tttacgctgc ttcttgcccg atcgtactaa ccgactttcg gcgttgcatc agccacaaat
     2041 acgcaatgcc atatggaaac tcgccagaaa gaaacaaaat tgtctggtca aagaaacgtt
     2101 ctcttctaag tttgaaaaaa cacgccgtaa tgaatatcag cggtttctta aaaaaggcgg
     2161 aagtgtaaaa agcgttgctg attgttcttc tgatgaactg actcatattt ttatcgagtt
     2221 atttcggtct cgtttcggca atacttcatc ctgctatccc gctgataacc ttgccaactt
     2281 ttttagtcaa ctgcatcacc ttctgtttgg gcatattctt tatattgaag ggataccctg
     2341 tgcatttgat atcgtactga aatctgaaag ccagatgaac gtctactttg acgtatctaa
     2401 tggtgcaatt aaaaatgaat gcaggccact cagtcccggc agcatactaa tgtggctaaa
     2461 tattagccgt gccagacatt actgccagga aagacaaaaa aaattgcttt tctccatcgg
     2521 catactaaag cctgaatggg aatataagcg catgtggtcg accccctatt ttaccgggaa
     2581 atcgatttgc taaaaagaaa gcctggacgt aaatatgttt tttacgccca ggtttttcat
     2641 aaaccctgat aaaatgataa aaaacgaaaa tttaatcaga atttaaaaaa taagttaacc
     2701 accatataat cata
//
LOCUS       DAJVKX010000248         2711 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.249, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000248 DAJVKX010000000
VERSION     DAJVKX010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2711
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.249"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(2..244)
                     /gene="cedA"
                     /locus_tag="OPY25_004474"
     CDS             complement(2..244)
                     /gene="cedA"
                     /locus_tag="OPY25_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HCS0929904.1"
                     /translation="MMKPLRQQNRQIISYIPRVEPAPPEHAIKMDTFRDVWILRGKYV
                     AFVLTGESFQRSPAFSVPESAQRWANQVRQENEIAD"
     gene            461..>2711
                     /gene="katE"
                     /locus_tag="OPY25_004475"
     CDS             461..>2711
                     /gene="katE"
                     /locus_tag="OPY25_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HCS0929905.1"
                     /translation="MSHNEKSPHQSPVHDTRESQPGLDSLAPSDGSHRPTPEPTPPGA
                     QPTAPGSLKAPETANDKLTALDAFRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLL
                     EDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKDLSDITKAAFLCDPQKITPVF
                     VRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAV
                     KPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAISDRGIPRSYRTMEGFGIHTFRL
                     INAQGKATFVRFHWKPLAGKASLVWDESQKLTGRDPDFHRRDLWEAIEAGDFPEYELG
                     LQLIAEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGH
                     IVPGIDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMDI
                     DTNPANYEPNSINDNWPRETPPAPKRGGFESYQERVDGNEIRERSPSFGEYYSHPRLF
                     WLSQTPIEQQHIIDAFSFELGKVARAYIRERVVDQLAHIDVTLAQGVAHNLGFALTHE
                     QTQIAPPPDVNGLKKDPALSLYAVPDGDVKGRVVAILLNDKVNAAELLTIFQALKAKG
                     VHVKLLYSRMGEVTADDGSTLTIAATFAGAPSLTVDAVIVPCGNIADIESCGDARYYL
                     LEAYKHLKPIALAGDARRFKALLNIDSQGEEGLVEADNVDHHFMDTLLTLMAAHRVWS
                     RAGKINAIPA"
BASE COUNT          650 a          756 c          689 g          616 t
ORIGIN      
        1 cttagtcagc gatttcgttt tcctggcgaa cctgattcgc ccaacgttgc gccgattctg
       61 gcacgctaaa ggcgggcgac cgttgaaatg actcccccgt cagaacaaag gcaacatatt
      121 taccgcgcag tatccagacg tcgcgaaacg tatccatttt tatcgcatgt tccggcggcg
      181 cgggttcaac acgcggaata tagctaataa tctggcgatt ttgctggcga agaggtttca
      241 tcattaatgc ttcactaaaa gaggctaagg ctaaaaatca gaaaaacact attttagccg
      301 atcttcgccc ccgacgtcct gttccgcgcg tgcgatttcc ccgttgtacc ctgtctgccg
      361 ttccgctctc ccccggcata attgctgaaa tgttctatag ttagagtgat tttgactact
      421 accacgccca tttcagtgat gaaagcagga gacgagttca atgtcgcata atgaaaaatc
      481 cccccatcag tcccccgtgc atgatacccg tgaatcacag cccggcctgg actccctggc
      541 accgtcagac ggttcacatc gccccacgcc agaaccgacg ccgccgggcg cgcaaccaac
      601 ggcccccggc agcttaaaag cgcccgagac cgcgaatgat aagctcaccg ccctcgacgc
      661 ctttcgtaaa ggcagcgaaa attatgcgct gaccaccaat cagggcgtgc gcatcgccga
      721 cgatcaaaat tctcttcgcg ccggcagccg tggccctacg ctgttggaag attttatcct
      781 gcgcgagaaa attacccact ttgaccatga gcgtatcccg gagaggatcg ttcacgcccg
      841 cggatctgca gcgcacggct atttccagcc atataaagac ctgagcgaca tcacgaaagc
      901 cgcgtttctg tgcgatccac agaaaattac cccggtcttt gttcgctttt cgacagtaca
      961 gggcggcgcg gggtctgctg ataccgtacg tgatatccgc ggttttgcga ccaaatttta
     1021 taccgaagag ggaattttcg atctcgtcgg taataacacg ccgatctttt ttatccagga
     1081 tgcgcataag tttccggatt ttgtgcacgc cgttaagccc gaaccacatt gggctattcc
     1141 gcaagggcag agcgcgcacg acaccttctg ggactatgtt tccttacagc ctgagacgct
     1201 gcacaacgtc atgtgggcaa tatcggatcg cggtattcca cggagttatc ggacgatgga
     1261 agggttcggc attcacacct tccgtctgat caatgcacaa gggaaagcga cctttgtccg
     1321 tttccactgg aaaccgttgg caggtaaagc ctcgctggta tgggatgagt cacaaaaact
     1381 gaccggtcgc gatccggatt ttcaccgccg ggatctgtgg gaggccatcg aagcgggcga
     1441 tttcccggaa tacgagctgg gcctacaact cattgccgaa gaggatgaat ttaaattcga
     1501 ttttgatctg ctcgatccga ccaaactgat tccggaagag ttggtgccag tacaacgcgt
     1561 cggcaaaatg gtgttaaacc gtaatccgga taactttttc gctgaaaacg aacaggcggc
     1621 atttcatcca ggacatattg ttcccggcat tgattttacc aacgatccgc tgttacaggg
     1681 gcgtctgttc tcttataccg acacgcaaat cagtcgtctg ggcgggccaa acttccacga
     1741 aattccgatt aaccgcccta cctgccccta ccataacttc cagcgtgacg gtatgcaccg
     1801 gatggatatc gacaccaatc cggcgaacta tgaaccaaac tccattaatg acaactggcc
     1861 acgcgaaacg ccgccagcgc caaaacgcgg cggcttcgaa tcataccagg aacgcgtgga
     1921 tggtaatgaa atccgcgaac gcagcccctc tttcggtgaa tattactcgc atcctcgcct
     1981 gttctggctc agtcagacgc cgatagaaca gcagcatatt attgacgcgt tcagctttga
     2041 gctgggtaaa gtcgcccgcg cgtatattcg ggagcgggtg gtcgatcagt tagcgcatat
     2101 tgatgtcacg ctggctcagg gcgtcgcgca taatctcggt tttgcactca cccatgagca
     2161 aacgcaaatt gccccgcctc ctgatgtcaa cggtctgaaa aaagatccgg cgctcagcct
     2221 gtatgcggtg ccggacggcg atgttaaagg ccgagtggtc gctattctgc tgaacgacaa
     2281 ggttaacgcc gccgaactgt tgaccatttt tcaggcttta aaagccaaag gcgtccacgt
     2341 aaaactgctc tattcacgga tgggggaagt aacggctgat gacggttcaa cattaactat
     2401 tgcggcaacc tttgccggcg cgccgtcgct aacggtcgat gcggtaatag taccgtgcgg
     2461 caatattgcc gatatcgaga gttgcggcga tgcccgttac taccttctgg aagcctacaa
     2521 acatctgaag cccatcgcac tggcaggcga cgcccgacgg tttaaggcgc ttttaaacat
     2581 tgatagccag ggggaagaag gacttgttga ggcagataac gttgaccacc actttatgga
     2641 cactctgctg acgctgatgg cggcacaccg tgtctggtcg cgtgcgggga aaattaacgc
     2701 gattcctgca t
//
LOCUS       DAJVKX010000249         2627 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.250, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000249 DAJVKX010000000
VERSION     DAJVKX010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2627
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.250"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            5..1366
                     /locus_tag="OPY25_004476"
     CDS             5..1366
                     /locus_tag="OPY25_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HCS0929906.1"
                     /translation="MFVCFFLAILPFFALSFPGIREYVFDNFMVSAIYNGVIIAIYIT
                     GSLCALFTILKNISAKDILIAQDASRKNSILSNLNQVLFAGEPKQCDFNLLMELDDNV
                     STARNQRLSFIMSCSNVSTLVGLLGTFAGLPITIGSIGNLLSSPSDVGGDNASNTLNM
                     IVTMVASLSEPLKGMNTAFVSSIYGVVCAILLTSQSVFVRSSYSLVSTEIKKLKIISN
                     RSNNKQRSLRVESETLVEFKELFKAFFDNYLTVENLRTQDEEKKRVMLSDSFVTLQNR
                     LLDNSAKLEQLSTLIDGYLVSNNENTKKLVDGVITITSRLSEGNTLLADNNARLEAMS
                     TIQNIIDKKNDSIMASVDKCYQESFSHGKTINDIAAGSADISHTLDGLRKEMDEDMNN
                     VHLALSDLSATDKKIIANTKEISAEMVSYRDTYMPLMEKITSMHQEIVKQRLLNKEEK
                     NED"
     gene            1356..>2627
                     /gene="siiC"
                     /locus_tag="OPY25_004477"
     CDS             1356..>2627
                     /gene="siiC"
                     /locus_tag="OPY25_004477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiC"
                     /protein_id="HCS0929907.1"
                     /translation="MKIKMFFLTTAFITQSTYASELPVIPLRDLVNAALTHQPSVAVS
                     YYETEKKNSDLDLSQAALYPTLDLTSGLNNNRKESSGTERNVENKVSLSYRITDFGVR
                     GANIRKSEYERDNSKTDYEKTKNIVSQEVVTTYYNISKYREMIDGVNLEKEFYKKMLE
                     TFSLLVSSGVAMQSDMRKVQVSIDALNTRSIMYQSMLDDEMYKMQNMTGLNLSPDQIQ
                     SDEKFNLFKKYIFVESPEKLMDMVMKYNDDYKMLVNTRKAATEDINAAKSSYFPTVDL
                     VSSYVQNNPSGSAKKSDYEDEFKTGINVSFNIFNGFRNAAQERKMVASYSQAKLQIDD
                     FLIKTRYNIDSQLSKYTAAKETYSVAERSHTNALQLTELYEQEFQLGQKSLLDLISSR
                     NEAFQAYVSMIDSKYSLYILKLQQLSLIFHLM"
BASE COUNT          870 a          454 c          517 g          786 t
ORIGIN      
        1 ctatttgttt gtctgttttt tccttgccat actccctttt ttcgctttat cttttcccgg
       61 tataagagag tatgtttttg ataattttat ggtttctgca atttacaatg gagtcattat
      121 tgccatttat attacaggtt ctttgtgtgc attattcact attcttaaaa atatttcagc
      181 aaaagacata ttaatagctc aggacgccag tagaaaaaat agcattcttt ctaacctcaa
      241 tcaggttttg tttgccgggg aacccaaaca gtgtgatttc aatttactga tggaattaga
      301 tgacaatgtg tctaccgccc gtaaccaacg attgtcattt attatgagct gtagcaatgt
      361 gtcgacgctt gttggcctgt tggggacgtt tgcgggtctg cctattacga ttggttcaat
      421 cgggaactta ttgagctcgc catcagatgt tggcggtgat aatgcaagta atacactcaa
      481 tatgattgtg acaatggtag cgtcgctttc tgaaccattg aaagggatga ataccgcatt
      541 tgtatcttct atctatggtg ttgtttgcgc catactcctg acctcacaaa gtgtttttgt
      601 tcgcagctcc tattcccttg tttctacaga gatcaaaaaa ttaaaaatca taagtaacag
      661 atccaataat aaacaacgaa gcctgcgggt tgaatcagag acgcttgtag aatttaaaga
      721 gttgtttaaa gcgttttttg ataactacct gacagttgaa aacttacgga cgcaggatga
      781 agaaaagaaa cgagtgatgc tatcagatag ctttgtcact ttgcaaaacc gactattgga
      841 taactcagca aaactggaac aactttctac gctgattgat ggttatctgg taagcaataa
      901 cgaaaatacc aaaaaattag ttgacggtgt aataacaatt acctctcgtt tatctgaagg
      961 taataccctg cttgctgata ataatgcacg actggaggca atgagtacaa tacaaaatat
     1021 tatagacaaa aagaatgatt caataatggc atcagttgat aaatgttatc aggaatcttt
     1081 ttcacatggt aagaccataa acgatattgc cgctggcagt gccgatattt ctcatactct
     1141 cgatgggctg agaaaagaaa tggatgagga tatgaataat gttcatttag cgctatccga
     1201 tctatcggct actgataaaa agattattgc caatactaaa gagattagtg ctgaaatggt
     1261 tagctatcgt gatacctata tgccattaat ggaaaaaata acatctatgc atcaggaaat
     1321 agtaaagcaa cgtttgttaa acaaggagga aaaaaatgaa gattaagatg ttttttctga
     1381 cgactgcttt tattacacaa agcacatacg ccagcgagct tccggtcatt cctctaagag
     1441 atttagttaa tgccgcatta acgcatcagc cctctgttgc tgtttcatat tatgagactg
     1501 aaaagaaaaa cagtgactta gatctttcac aggcagcact ttatcctacc ctggatctaa
     1561 cctctggcct taataataac agaaaggagt cgtcaggtac cgagagaaac gttgaaaata
     1621 aggtatcttt atcataccga ataacggatt ttggagtgag gggggctaat atcaggaaat
     1681 ctgaatacga aagagataat agtaaaactg actatgaaaa aacaaagaat atagtgtctc
     1741 aggaggttgt gacaacctat tacaacatca gtaaatatcg tgaaatgatt gatggcgtaa
     1801 atctggagaa agagttttat aaaaagatgc tggaaacttt ttcgctactg gtatcttccg
     1861 gtgtagctat gcaatctgat atgcgtaaag tacaagtatc tatcgatgca ttaaatacca
     1921 gaagtattat gtatcagtcg atgctggatg atgaaatgta taaaatgcag aatatgactg
     1981 gtctgaattt atcaccagat cagattcaaa gcgatgaaaa attcaacctc ttcaaaaaat
     2041 atatctttgt cgaaagccct gaaaaactta tggacatggt gatgaaatac aacgatgact
     2101 ataagatgct tgtcaatacc cgaaaagctg cgaccgaaga tattaatgcc gcaaaatcat
     2161 cctattttcc gactgtagat ctcgtttcca gctatgtaca gaataatccg agcggtagtg
     2221 ccaaaaaaag tgattatgaa gatgaattta aaacgggtat caatgtcagt ttcaacattt
     2281 ttaatgggtt tagaaatgca gcccaggaaa gaaaaatggt ggcaagttac tcgcaggcta
     2341 agctgcaaat tgacgatttc ttgattaaaa ctcgttataa cattgattca caactttcaa
     2401 aatacaccgc tgcaaaagag acttactcag tggcggaacg ttcacataca aacgcgttac
     2461 agcttactga attatatgag caggagtttc agttagggca aaaaagtttg cttgatttaa
     2521 tttcaagccg taatgaagca tttcaggcat atgtaagcat gatcgacagc aaatatagcc
     2581 tgtatatttt aaagctacag caactctcat tgatttttca tttaatg
//
LOCUS       DAJVKX010000250         2524 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.251, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000250 DAJVKX010000000
VERSION     DAJVKX010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2524
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.251"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..2508
                     /gene="cas3"
                     /locus_tag="OPY25_004478"
                     /pseudo
     CDS             1..2508
                     /gene="cas3"
                     /locus_tag="OPY25_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192071.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
BASE COUNT          645 a          620 c          628 g          631 t
ORIGIN      
        1 atgcagaaaa ctggataatc tggtttcttg ccagccacga tatcggaaaa ttcgccagag
       61 gatttcaaaa atacgccgaa ttcccagact ctcccttagt ctctcccatt agcggtgttt
      121 ccgcatttga gagacatgat tccttaggct tctatttatg gggtaaatta tttgaagcgt
      181 ggagttcagg tagtaatgaa attatcgcag gcattgaacc agaaaatcgc gctaggtttg
      241 aaagcgcttt aaatagctgg atgcttatta gcaccgggca ccatggcatc ccgccggaca
      301 ccatgaaaaa tagaagctcg ctggcattca ccgatgaaga cattgtcgca gcaacgcatt
      361 atctggaagc attaagtgaa ttattccctt tcactctacc tcaggaatgg aaaaccaaag
      421 cagggagaaa atgtttaaaa cagcacagtt ggtttttcgc tgggcttgtc accctcgccg
      481 actggatggg ctcggatgaa agccagtttc cactgctcag cagcgccatg ccattgaaag
      541 attattggcc tctcgcttgt gaaaaagccc aacaggccat cctccgaatg ccgccgttat
      601 ctcagcacag ccattatcaa gatcaccggg cattatttcc gttcattcag acgctcaccc
      661 ctcttcagca acgagcaagc gaactggata tttcagcacc cggtgcacag ctggttgtcc
      721 tggaagacgt taccggagca ggcaaaacag aggccgcact gattctgact caccgcttaa
      781 tgtcagccaa taaaggccac ggtctctacg ttgggttgcc gacaatggcc accgcaaacg
      841 ccatgtatca gcgcctggca tcggcttatc atgcgctatt taccgatgag tccaggccat
      901 cgctcatcct ggcacacggt gggcgagaaa tgtcggactc tttccgacaa tccatctggc
      961 agccaacaga aaatatagct gaagattatg cccgtgatga tggcaacgcg actactgagt
     1021 gccatacctg gtttgcagat tcacgcaaaa aagcgctgct ggcggaagtc ggcgtaggta
     1081 cgctggatca actcttaatg gcggtgatgc cttttcgcca tcaatcgctc cgattgctag
     1141 ggatgcgcga caaaatcctg ctgctggatg aagtgcacgc ctatgatggt tatatggtta
     1201 aattgctgga aggtttattg cgcttccatg ccgcccaggg cggtagcgct attattctga
     1261 gcgccactct tcccgccgct ttacgggaaa aattacttaa tgcgtttagc gatggcgcgg
     1321 aatttatgag cgctggtggt agcgataacg cgggttatcc atggttaagc cacctcactt
     1381 cctccggtct gttagagcaa ccactggcca cacgtcccga agtccaaagg actgtagccg
     1441 ttaattggat acagcagcgc caggaagcac tggacattat ttatcgcgtt gtggcaaccg
     1501 gacagtgcat ttgttggatc cgcaacacgg ttgatgatgc gctggacact taccagcagt
     1561 tgctacacga gggaatcgtt ccagagcagg atcttttgct tttccacagc cgttttgctt
     1621 ttatcgatcg tattgctatt gaaaataaaa cgttaaactg gtttggtaac aatgcccccg
     1681 tttctgaacg acgtggtaag gtattaatcg ccacacaagt cgttgaacaa agtctcgatc
     1741 tggactttga ctggatgatc accgatctgg cgccgattga tttattgatc cagcgcgccg
     1801 gtcgcctgca acgccatatc cgcgatgccc atgggcaacg aaaatctacg cttccggatg
     1861 aacgccagcc accagtattg catatttctg gcccctcact ggcaggagca ggcagaagag
     1921 ggctggttgg ggcaagagct aaaaggtacc ggctttgttt acaccgatca tgcctgcctg
     1981 tggcgtaccc aggcgctgct gcgtcaacat ggtgagatcc gtatgccgga taatgccaga
     2041 gcactcgttg acggcgtata cgagcagaaa attgctgcgc cagcaggctt gcagacgatc
     2101 tctgacgttg cctttggcaa agtccttagc caacgttcag tggctgcgca aaatttatta
     2161 cgttacgatc tcggttacga tcgagaagcc agcgactttt tatgggataa agatagagaa
     2221 ttttctaccc gtctgggtga agagagtgtt gatgtttatc tcgccagaaa agacattgat
     2281 ggacagctac gccctttagt tgatgaaata gatttctgct gggaaaaaag tcgcttatcc
     2341 gtccgaaaat catggtggca aaaaaattct ggtacattcc aatgtccaga tgaggaaaca
     2401 ttagcctgtt tcagaaaacg ccaccatcgc ccttccggac agattgtgct ggtatctgat
     2461 accggagaag ctagctatta cagtaaacgt tttggattgg ttggataacg ggtattattc
     2521 taac
//
LOCUS       DAJVKX010000251         2494 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.252, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000251 DAJVKX010000000
VERSION     DAJVKX010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2494
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.252"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(127..954)
                     /gene="dkgA"
                     /locus_tag="OPY25_004479"
                     /pseudo
     CDS             complement(127..954)
                     /gene="dkgA"
                     /locus_tag="OPY25_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462080.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
     gene            complement(1060..2223)
                     /gene="yqhD"
                     /locus_tag="OPY25_004480"
     CDS             complement(1060..2223)
                     /gene="yqhD"
                     /locus_tag="OPY25_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCS0929908.1"
                     /translation="MKNFKLHTPTRILFGKGAIVDLRDQIPQDARVLITYGGGSVKKT
                     GVLAQVQDALKGLDVREFGGIEPNPSYETLMKAVQLVRDESITFLLAVGGGSVLDGTK
                     FIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAE
                     GILLTLIEEGPKALQEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDDERIDAAIAATRRFF
                     EQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR"
BASE COUNT          571 a          643 c          659 g          621 t
ORIGIN      
        1 atcagaataa ttctgcgctt gtgtgtgggg gaaatatact gttaaatgcg cgtaattgtt
       61 tcttaatgtt tcggaatgca aaaaagcccg acgacatcgt cgggcatggc gtgcgataaa
      121 tccggcttaa ccgccggact gatccggatc gggcccgagg cgttttcctt gatccagttt
      181 tgcgatctcg cctaattcat ctttatcgag acggaaatcc cagacagcaa agttttccgc
      241 gatacgggaa ggagtgacgg atttcggaat gactaccagc ccgcagtcca gatgccagcg
      301 aataacaatc tgggcgggcg ttttgccgta tttatccgcc agttcgcgaa tcactttctg
      361 atcgaatacg ccttcgccgc cctgcgccag cgggctccag gactcggtct ggattttatg
      421 cgtcgcattc tacgcatgta gctggcgctg ttgcatcaag gggtgaagct cgatctggtt
      481 gatcacaggg ggaacgccgg tttcatcgat cagacgctgg aggtgatgga tctgaaagtt
      541 acagaccccg atactcttta ccagcccctc tttttgcagc gcgatcatgc ccttccaggc
      601 gtcgacatag tgatcgatag ccggtacggg ccagtgcatc agatagagat cgagataatc
      661 aagttgcagt tttttcagac tctcctgcag ggcttcgcgg ggacgttttt gatcgtcatt
      721 ccacaactta gtggtgataa acagctcttc ccgcgccacg ctcgctgctt ttagcgcttt
      781 gccgacgcct tcttcattct gatatgctgt ggcggtatca atcgatcgat agcccacctc
      841 cagcgcttta tgaatcgccg cgatcacctc ttcattgctt gctttccaga ctcccagccc
      901 aagttgtggc attacgttgc catcctgtag cctgataatg gttggattag ccatgatgtg
      961 ttcctctttt aattggctcg ccggagtcgg gtccggcgag actaagtgac ttaagtctgg
     1021 acgaaatggc caaaaacgaa agtcagaggc gaaaaaacct tagcgcgccg cttcataaat
     1081 ccgacggctg acatccagcg taatatcctg attttcacct aaatttgtgc atccatgcgc
     1141 ctcaagtttg gccagtagcg ccggaatagt gctgccatcc agaccgtaat cggacaggtg
     1201 ggtaggcacg cccatctgtt cgaagaaacg gcgggtggcg gcaatggcgg catcaatacg
     1261 ctcgtcgtcg gaaccgtcgg tgatattcca tacacgttca gcgtattgca ggagttttgc
     1321 gcgtttaacg tctcgttttt cgttccatag cgcaggcaga atgatagcca gcgtctgggc
     1381 atgatcgaga ccgtgcatcg ccgtaagctc atggcccagc atatgcgtcg cccagtcttg
     1441 cggaacacca gcgccaatca ggccattcaa tgcctgagta gcggcccaca tcacgttagc
     1501 gcggacgtca tagttttcag gctcttgcag cgctttggga ccttcttcga tcagtgtgag
     1561 taaaatacct tcggcgaaac gatcctgaat tttgccgtta acggggtaag tgacgtactg
     1621 ctcaacggta tggacgaaag catccacgac gccgttcgca acctggcgcg gcggcaatgt
     1681 ataggtgtag accgggtcca gtacggcaaa caccggttgc acgaacgagg agtggaaggc
     1741 ctgtttgtcg ccagtagttt tacgggaaat gactgcgccg gcgttcgatt ctgagccggt
     1801 tgccggtagg gtcagcacag accccatcgg gattgcgcta cgaatctcag taccgccggt
     1861 ttccagaatg tgccacggat cgacgccgtc cgtatactgc gccgctgcgg cgataaattt
     1921 ggtgccgtcc agtacggaac cgccgccaac ggccagcagg aaggtaatac tttcgtcgcg
     1981 cacaagctgc acggccttca tcagcgtttc ataggacggg ttcggttcaa taccgccaaa
     2041 ctcccgaaca tccagtcctt ttaacgcgtc ctgaacttgc gccagtacgc cggtcttttt
     2101 cacgctaccg ccgccatagg taatcagcac gcgggcgtcc tgcgggatct gatcgcggag
     2161 atcgacgata gcgcctttac caaacagaat gcgggtaggg gtatgtaatt tgaaattttt
     2221 cattgctcat tcccttatgt gggtaaaaag agggcaggcg gctgtctgcc tgatggtcat
     2281 cattgtggtc ttgtgagaga tgtctctcaa tgcacatttc tgccaatgtt ttgcctattt
     2341 ctccagaatg ctggagaaaa tcgctaaaaa tgcgcacaat ccagcggagt ggatttgata
     2401 aaaaaatggc gcgttatgaa tcgtgaagca atttgcttac agttggctga taaaattaat
     2461 catttaaaaa ataatgataa aataatcagc gagc
//
LOCUS       DAJVKX010000252         2387 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.253, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000252 DAJVKX010000000
VERSION     DAJVKX010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2387
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.253"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(46..482)
                     /locus_tag="OPY25_004481"
                     /pseudo
     CDS             complement(46..482)
                     /locus_tag="OPY25_004481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308311.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(861..1286)
                     /locus_tag="OPY25_004482"
     CDS             complement(861..1286)
                     /locus_tag="OPY25_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subtilase cytotoxin subunit B-like protein"
                     /protein_id="HCS0929909.1"
                     /translation="MKKKLKVLTLALASISSVCYAAMADYDTYVSNVQINNLSYGVYT
                     SGGKETQFFCIGLKHGSEAISINAMCKVDVYGNHKQGFDNMLNTAKYYYTTGGDVRIY
                     YKENVWRDPDFKSAFSSRELIAITTCSSSSYCMGPTVTN"
     gene            complement(1213..1512)
                     /locus_tag="OPY25_004483"
     CDS             complement(1213..1512)
                     /locus_tag="OPY25_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001640522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pertussis toxin subunit"
                     /protein_id="HCS0929910.1"
                     /translation="MYRYRIRADNSFYSLPPSVAYIELCGIQFGHFERVMMRLQSEYV
                     SVNSIPIENIHEAVELVYDRNTSMVNIVGVDYEKEIKGSDSCSCVNIQCLLCSYG"
     gene            complement(1551..1691)
                     /locus_tag="OPY25_004484"
     CDS             complement(1551..1691)
                     /locus_tag="OPY25_004484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001605117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pertussis toxin subunit"
                     /protein_id="HCS0929911.1"
                     /translation="MIFRDGFASHGNNRNLQQHIRDDSCVSGSRDSTILRLSQILMRL
                     II"
     gene            complement(2046..2315)
                     /locus_tag="OPY25_004485"
     CDS             complement(2046..2315)
                     /locus_tag="OPY25_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001766201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinG"
                     /protein_id="HCS0929912.1"
                     /translation="MAKLPRRKCKVCREWFPPAYSNVVWCCPEHGAIYALELRAKEKS
                     KAAARCIRGKHQADKAERQANGCMLRERQAVLYTLSRKMFRKHLR"
BASE COUNT          667 a          631 c          449 g          640 t
ORIGIN      
        1 gcagtccatg cttcgatgat gattgccgga gatttatctt ctctatcagc gcctccgggt
       61 ttcactgcgt gatgctgcag gaagttttct gtacagcgtc gacagccccc ataaataatc
      121 gttacctgct gtcgcagtac ttctgaccca atcagacgcc gggcctgcgc ctattgttcc
      181 aatgttagtt tcggtcgtcg gccaccatta cgccccctcg cccttgccgc ttccagtcca
      241 gcgcgggttc tttccacaat caattcacgt tccatttcag cgagtgcgcc catgacatga
      301 aagaagaatc gccccattgg cgtcgacgtg tctatgctgt cggtcaggct gcggacatta
      361 acgccgcgtt cgcgcaattc ttctaccaga acgaccagat gacgcatact gcgacccagg
      421 cgatcacgct tccatacaac cagtatgtcc ccttatgata acgtcctgac taaaaggaac
      481 aggcttcacg ggctggattt atccaacaaa gcgcgtagtg agtgcttccc gttagcctga
      541 atacgaaaaa ggccacgtaa atgcgcagcc tttatggtga gagttctaat cttaagaggc
      601 actccatcaa acaaaccacc cacagttgtc agaagcttga aggagtgctt tggggtgaca
      661 gtatctgcgg cattgttgcc acgaacaacg ttcccgcaaa tgctcaaaat acaatcccaa
      721 aatccgctcc agtaaacggt ctgaatatcg ttgccccaca gatcgctaca gccatacagg
      781 aacctgataa aggttcagac ataatcgtct caccaacaag attaagcctg ttctttagag
      841 cgtttaatac ccagcaacat ttaatttgtc accgtaggcc ccatacaata acttgatgag
      901 ctacaagtag ttatcgcaat taattccctg gaagagaatg cacttttgaa atcggggtcg
      961 cgccaaacat tctctttata atatatcctt acatcccccc ctgttgtata ataatacttt
     1021 gctgtattta gcatgttatc aaacccctgt ttatgattcc cgtacacatc cactttacac
     1081 atggcattga tactaatagc ttcactcccg tgcttcagtc cgatacaaaa aaactgagtt
     1141 tccttacccc ctgacgtata cacaccataa gacaggttgt taatctgaac attactcaca
     1201 tacgtatcat aatcagccat agctgcataa caaacactgg atattgacgc aagagcaaga
     1261 gtcagaacct ttaatttctt tttcataatc cactccaaca atatttacca tacttgtatt
     1321 tctatcgtaa acaagctcaa ctgcttcatg gatattttca attgggatag aatttacaga
     1381 tacatactca ctttgtaacc gcatcatcac tcgctcaaaa tgaccaaact ggataccaca
     1441 taactcaata taagcaacag acggcggaag gctgtagaaa ctattgtctg cacggattct
     1501 gtatctgtac aacctgccgc taaatgttgc tctggagtaa tataatcgtg ctatattata
     1561 agcctcatta atatctgaga tagtcgcaat atagtactgt ctcgactacc ggatacacag
     1621 gagtcatctc ttatatgttg ctgaagattc ctgttatttc cgtgagaagc aaaaccatcc
     1681 cgaaaaatca catctgaagg tctcgagtca acacgatata caaaatcaac ggcacctgaa
     1741 tgaccaaaaa aatactaaaa ataatattac ttttttatca tactctctcc tacagaaact
     1801 atcaggcaaa ccacctaatg tgttaaaccg agtgctaacc atagctcagt catactttac
     1861 gtctcgctgg ataaaattag aaaaacaaac ctccccggtt tacgggcacg aaaatcccgg
     1921 taattgcgca atgccgatcc ttaaactgcg gcactataac ggcttcccct acagggagcc
     1981 gttttgttat gtcacttctc aatgacctgc tcgatttcag cgaccatccc cttatgccac
     2041 cgccttcagc gcagatgttt gcggaacatc ttcctgctga gtgtatacaa cactgcctga
     2101 cgctctctaa gcatgcaacc gttcgcctgg cgttcggctt tatccgcctg gtgtttacct
     2161 ctgatacacc tggctgcggc tttactcttt tctttggcac gcagttccag cgcgtagata
     2221 gcaccatgtt caggacagca ccagacaacg ttgctgtaag caggaggaaa ccattcccga
     2281 caaactttgc atttacggcg cggtaattta gccatgctca cctcagaccc ggttacggat
     2341 atagcatcta ataacgttag attatgcatg cctgacattg ttaggcg
//
LOCUS       DAJVKX010000253         2302 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.254, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000253 DAJVKX010000000
VERSION     DAJVKX010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2302
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.254"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..241
                     /locus_tag="OPY25_004486"
     CDS             <1..241
                     /locus_tag="OPY25_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4427 domain-containing protein"
                     /protein_id="HCS0929913.1"
                     /translation="KVNKEGRYLLDVNLASVDWPLRRKEAFASHVAGWLKHRFDIEAG
                     RYSVRGKDDYDAIPSYETPLKDQHPFYNHTVNVDW"
     gene            complement(400..1491)
                     /gene="ychF"
                     /locus_tag="OPY25_004487"
     CDS             complement(400..1491)
                     /gene="ychF"
                     /locus_tag="OPY25_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCS0929914.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVAGKVNPAEDIDVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAALEKCLPHLAEAGMLRSLDLTDEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDDERDEFMAELGLEEPGLNRVIRAGYRL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTIAFDDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDIMNFLFNV"
     gene            complement(1608..2192)
                     /gene="pth"
                     /locus_tag="OPY25_004488"
     CDS             complement(1608..2192)
                     /gene="pth"
                     /locus_tag="OPY25_004488"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCS0929915.1"
                     /translation="MAIKLIVGLANPGAEYAATRHNAGAWYVDLLAERLRAPLREEPK
                     FFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGAMASFYRIQPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTELWFKEGLAKATSRLHTFKAQ"
BASE COUNT          559 a          580 c          551 g          612 t
ORIGIN      
        1 caaggttaat aaagaagggc ggtacttatt agatgttaat ttggcttctg ttgattggcc
       61 attaagaaga aaagaggctt tcgcaagtca tgttgcggga tggctcaaac atcgttttga
      121 tatcgaagcg ggaaggtatt ccgttcgggg aaaagatgat tatgatgcga tcccaagtta
      181 tgagacgccg ctaaaggatc agcatccttt ttataatcat acagtgaatg tcgactggta
      241 attaagaaaa aaacttaccc tgttagctct gcgttaattg agcctgtcag tatgagttga
      301 gatattatga aataaaaaat ccacgcggct gcgtggattt tatgagtttc tttgcctctt
      361 atgagattca gcaaaacctc ataagacaac aatttttact tagacgttga acaggaagtt
      421 cattatatcg ccatctttaa cgatataatc tttgccttcc gctcgcatct taccggcttc
      481 tttcgcgcct tgttcacctt tataggtaat aaagtcgtca aaggcgatag tttgagcgcg
      541 gataaagcct ttttcgaagt cggtatggat tttacctgct gcttgcggcg cggttgcgcc
      601 aaccggaatg gtccatgcgc gaacttcttt caccccggcg gtgaagtagg tctggaggtt
      661 cagcaggcga taaccagcgc gaataacgcg gttcagcccc ggttcttcca gacccagttc
      721 agccataaat tcgtcacgct cgtcatcatc cagctcagca atatcagctt cgacggcggc
      781 acacaccgga accacgaccg aaccttcttt cgcggcgatt tcgcgaacct ggtccagata
      841 cgggttattt tcaaaaccgt cttcattgac gttagcgata tacattgtcg gcttcagcgt
      901 caggaagctt aaataacgga tagccgcttt atcttcgtcc gtcaggtcca gcgaacgcag
      961 catccccgct tcggccaggt gcggcaggca tttttccagc gcggccagtt ccgctttggc
     1021 gtctttatcg ccgcctttgg ctttcttctg tacgcgatgg atcgcgcgct cgcaggtatc
     1081 gaggtcagcc agcgccagct cggtattgat aacatcaata tcttctgccg gatttacttt
     1141 acccgccacg tggatgatat tgtcgttctc aaagcagcga accacgtgac cgatagcttc
     1201 ggtttcacgg atattggtca ggaactggtt acccaaccct tcgcctttgg atgcgccttt
     1261 taccagaccg gcgatatcca cgaactccat cgtggttggt agaatgcgtt gcggtttaac
     1321 aatctcagcc aactggtcca gacgcggatc gggcatcggc acgacaccgg tattcggttc
     1381 gatagtgcag aacggaaagt ttgccgcttc aataccggct tttgtcagcg cgttgaacag
     1441 ggtggatttc ccgacgttgg gcagaccgac gataccgcat ttgaatccca tgatttaact
     1501 caccttaata tcttaataat caacctgtta tagaaaacag attgcagaaa tggaaataac
     1561 ttcgcctatt atacacggcg tgcggcaaaa atgccgcaca tcactggtta ttgcgcctta
     1621 aaggtatgca aacggcttgt tgctttggcc agaccctctt tgaaccacaa ttccgtacag
     1681 cgcgccgctt cgtcaatggc ctcatcaatt aatttttgtt cagaaacagg gggtttaccc
     1741 agcacgaaac caacaacttt atttttatcg cctggatgac caattccaac gcgtaagcgg
     1801 tgaaagttgg gattattgcc cagcttgctg atgatgtctt tcagaccatt gtggccgccg
     1861 tggccgccgc caagtttaaa tttcgcgacg cccggcggga gatccagctc gtcgtgagcg
     1921 accagaattt cgtccggctg aatacggtaa aaactggcca ttgcgccaac tgctttacca
     1981 ctgaggttca tgaacgtggt gggtaccagc aggcgaacat cttccccttc cagcgtgatg
     2041 cgtgaggtat agccaaagaa tttaggctct tcacgcaacg gcgcgcgcag gcgctccgcc
     2101 agtaaatcga cgtaccatgc gcctgcattg tgtcgcgtcg cggcatattc cgcgccggga
     2161 ttcgccagac caacaatcaa tttaattgcc acgttttttg tcctgagtag atccatgact
     2221 ggcgcgtagt ttactgtctg tctgcccgct tgacaaaaca cagcgacact ctgaagtaaa
     2281 ttaaataatt gccagcattg at
//
LOCUS       DAJVKX010000254         2246 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.256, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000254 DAJVKX010000000
VERSION     DAJVKX010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2246
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.256"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1071..1484
                     /locus_tag="OPY25_004489"
     CDS             1071..1484
                     /locus_tag="OPY25_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subtilase cytotoxin subunit B"
                     /protein_id="HCS0929916.1"
                     /translation="MYMSKYVPVYTLLILIYSFNASAEWTGDNTNAYYSDEVISELHV
                     GQIDTSPYFCIKTVKANGSGTPVVACAVSKQSIWAPSFKELLDQARYFYSTGQSVRIH
                     VQKNIWTYPLFVNTFSANALVGLSSCSATQCFGPK"
     gene            1501..2229
                     /gene="artA"
                     /locus_tag="OPY25_004490"
     CDS             1501..2229
                     /gene="artA"
                     /locus_tag="OPY25_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pertussis-like toxin subunit ArtA"
                     /protein_id="HCS0929917.1"
                     /translation="MKKLIFLTLSIVSFNNYAVDFVYRVDSTPPDVIFRDGFSLLGYN
                     RNFQQFISGRSCSGGSSDSRYIATTSSVNQTYAIARAYYSRSTFKGNLYRYQIRADNN
                     FYSLLPSITYLETQGGHFNAYEKTMMRLQREYVSTLSILPENIQKAVALVYDSATGLV
                     KDGVSTMNASYLGLSTTSNPGVIPFLPEPQTYTQQRIDAFGPLISSCFSIGSVCHSHR
                     GQRADVYNMSFYDARPVIELILSK"
BASE COUNT          672 a          406 c          455 g          713 t
ORIGIN      
        1 cttaatagag actgcataat attatattga caagcttatt atcaggctct ttaaaagagc
       61 tttaaatgat catgagcaca tacttcttaa ggtaggcagt aactgctttt atatttatta
      121 tagcaggacc gctctggcag atacctgtgt ggcacctcag tatggcctga aaaatagagg
      181 aatatggacc agcagaagcg cctgctggct acttttcact taaatcgctg gaattcaccg
      241 gcgctacaga tgaagcgacc ttaacagtca tcaggtgtcc tgcattacca caggagtgat
      301 ttactggcta tcgatattcc tgctcatcag gtttttacgc catctacgca catttattct
      361 gctataagtt gaaatactgc aaaaaatatt aaggcttatt attttttctt taagcaaatt
      421 ttcgttcaac aaacttggat gcgggaatgt gtgaaatatc atttctttat actagaactc
      481 agcgacctac agctcacaac tttattagat cctcttcctg aatatattac ttttctggca
      541 gttatcaaca ataggctgac taaattgccg gacactttgc ctggagggta cagacagatt
      601 acgcgggtag gatcactaca ccgggaaaag attgccagtt aatgggatgt cgtccatgtt
      661 tcagttggag gataatgatt tatttccccc tctttgaccc tacaatagtg atctgatagt
      721 tatcctgaac gttcttacag agggcgggct tgttaaataa tcatcaagtt attaatgagt
      781 tatgtcctgc tttgctgaaa ataaaaatca gtagacagac gacggcgaac aatatgagcc
      841 ggaagtgcct gtgttattac tgtggcgtga attctgtaac tgataaagta ggtgtgctta
      901 ttatcagtaa tgaaattttt tatatatgta ttattactat tcacaggtaa tttgattgtt
      961 tgttgtgagt aacattgtgt tgaagtaaac catgatagac tggactgtga tgtggtgaga
     1021 tataatgaat ttgtgtttta ttaattattt taaacgtaca ggagagtagt atgtatatga
     1081 gtaagtatgt acctgtttat acattattaa ttctcattta ttcttttaat gccagcgctg
     1141 agtggacagg agataatacg aacgcctact actcagacga agttatcagt gaattacatg
     1201 ttggtcagat agatactagt ccttattttt gcataaaaac ggttaaagct aacggtagcg
     1261 gtacaccagt tgttgcatgt gcggtatcaa agcagagcat atgggcgccc tcctttaaag
     1321 aacttcttga tcaggcaaga tatttttaca gtacagggca atccgtaagg attcatgttc
     1381 aaaaaaatat ctggacctat ccgctttttg ttaatacctt ttcagcaaat gctcttgtgg
     1441 gactatcatc gtgcagtgcg acacaatgct ttggacccaa gtaagagggg agaagaaata
     1501 atgaaaaagt taatattctt aaccttatct atagttagct ttaataacta tgctgtagat
     1561 tttgtgtatc gtgtggactc aaccccgccg gacgttattt ttcgcgatgg gttttcacta
     1621 cttgggtata accgtaactt tcagcaattt attagtggaa ggtcatgtag tggtggaagt
     1681 agtgacagtc gctatattgc aacaacctca agtgttaatc aaacatatgc tatagccaga
     1741 gcgtactatt ctcgctcaac attcaaaggt aatttataca gatatcagat tcgtgcagat
     1801 aataatttct acagcttgct cccatccatc acctatctgg aaacgcaagg tggtcacttt
     1861 aatgcttatg aaaaaacgat gatgcgattg caaagagagt atgtttccac attatctatt
     1921 ttacccgaga atattcaaaa ggccgtggcg ctagtttatg atagcgcaac cggtctagta
     1981 aaggatggtg taagcacaat gaatgccagt tatttaggtt taagcactac gtctaatcct
     2041 ggtgtgatac cttttcttcc ggaaccgcag acgtataccc aacaacgaat tgatgcattc
     2101 ggcccattaa taagttcatg cttttcaata ggtagcgtat gtcattcaca tcgagggcaa
     2161 agagctgacg tatacaacat gtctttttat gatgcaagac ctgtaataga acttatactt
     2221 tctaaataaa tgaaacttac ctatgt
//
LOCUS       DAJVKX010000255         2225 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.257, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000255 DAJVKX010000000
VERSION     DAJVKX010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.257"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            224..658
                     /gene="uspF"
                     /locus_tag="OPY25_004491"
     CDS             224..658
                     /gene="uspF"
                     /locus_tag="OPY25_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HCS0929918.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEAEAKIDDAKVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEAIIKKFNLPADRVQAHVAEGSPKDKILEM
                     AKKLPADMVIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            complement(711..1049)
                     /locus_tag="OPY25_004492"
     CDS             complement(711..1049)
                     /locus_tag="OPY25_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HCS0929919.1"
                     /translation="MTKEAVIFLFIAIVVEVIATISLKLSDSFTRLVPSLVTIIGYCI
                     AFWCLTIPMRTIPAGIIYAIWSGVGIVLIGLIGWLFLGQKLDVPAIIGMLLIICGVIV
                     INLFSKSVSH"
     gene            complement(1324..2099)
                     /locus_tag="OPY25_004493"
                     /pseudo
     CDS             complement(1324..2099)
                     /locus_tag="OPY25_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4765 family protein"
     gene            complement(2106..2225)
                     /locus_tag="OPY25_004494"
                     /pseudo
     CDS             complement(2106..2225)
                     /locus_tag="OPY25_004494"
                     /inference="COORDINATES: protein motif:HMM:NF027292.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4765 family protein"
BASE COUNT          598 a          548 c          449 g          630 t
ORIGIN      
        1 acggtaacat ctctttttag gtctttcctg acaaggcaga aataacgttt taacgtcaac
       61 tcgctgatta tttacgggga atgcgcttaa tattacgccg tcctcccctg ttggtagtcc
      121 ccccagagta tcgtggagca gcacctaaaa tgtgacgtat gtcattgtac ataaagtgcc
      181 tttagggagt agaatttcag tggatactta aacaggaggt tttatgaaca gaacgattct
      241 tgtacccatc gatatttcag attcagaatt aactcaacgc gtgatttcac atgttgaagc
      301 cgaagcaaag attgacgacg ctaaagtgca ctttttgact gtaatcccgt ctttgcccta
      361 ttacgcttca ctgggactgg cttattcagc agagctcccc gcaatggacg atttgaaagc
      421 cgaagccaaa tctcaactgg aagcgattat caagaaattc aaccttcccg cggaccgcgt
      481 gcaggcgcac gtggcagaag gctctcctaa agataagatt ctggaaatgg caaaaaaatt
      541 accggccgat atggtgatta tcgcctcgca tcgtccggat attactacct atctgttggg
      601 ttccaacgcc gcagccgttg tgcgtcatgc ggaatgctcc gtactggtgg tgcgctaaat
      661 acccgagccc gcataagaga gtgcgggctc aaatcaacca tcatcatcgc ctagtgactg
      721 acgctttttg aaaacagatt gattacgatt acaccgcaga tgataagcaa catgccaata
      781 atagccggca catccaattt ttggccaaga aacagccatc ctatcaatcc aataagaaca
      841 atccctaccc cagaccaaat ggcataaatg atacccgcag ggatggttcg catagggatg
      901 gtaaggcacc agaacgcgat acaatatccg atgatggtaa cgaggctcgg taccagacgc
      961 gtaaaactat ccgataattt taatgagatc gtggcgataa cttctaccac gatggcgata
     1021 aatagaaaga ttacagcttc tttagtcata catctcttcg ttccgatatt ttcctggtcg
     1081 tggtgacatc ttaattaata cggatgacag aataaagacg cttttgaccc gttgcgtatc
     1141 tcgccataac ctacttcaag ttgcatgtgc tgcagctgcg ttcccttacc ccagtcactt
     1201 acttgagtaa gctcctgggg attcgctcgc ttgccgcctt cctgcaactc gaattaatta
     1261 aagtataaaa gcaacctttc atacacgaga gataacaaca ataaacctgt tcaggattta
     1321 tgattactta gaagcgtttg cctgccccgt attttctgct ttaccatatg tcctgtcaat
     1381 tataccaaca gggtccactg gtgtgttttt tggcataacc cagccacttt cactgacact
     1441 acctcgtgta agatatttga cttttaccct aacgataata agataatgtt ccctgctgaa
     1501 cctgtcggca acactaagat cggtggtata ttcaggtacg attcttccac ttcgaacctg
     1561 ctctttggct atttcagcag agacaggcaa tacctctaca tcgccccctc aataccgcct
     1621 gctgttttaa aactaacaat attttcagcc tgcggaccta ttgtacctcg gcataataca
     1681 acttcagtct cccctgctac agcatcccca ctctggtatt tcttataaat actttgtaca
     1741 ttttcttctg atgtagggta taaattttct gacagagagg ccagtatatc ttccagtaag
     1801 ggggaatcat ccgtaatatc cagaagctct tcatcataac ccgtgtctcc ttctcttaac
     1861 tctgaataag gcttatcaat atggcgaata agccccccac ctttcagccc tgacgcctga
     1921 taaaatcttc catcagaaga tcggtaaaat gttatggctg aattttttcc gctatccgaa
     1981 taggttgcct gatacgtttc tgaaccgggt tctttagtta aaacgagctc tctgtcgcca
     2041 tattttatcg tattaggcgc ttccgatgac agcggtggat atgaggcttg ttttctgtag
     2101 cgtccccctg ccatagatgt aacgtgttca aataggccat ctaacacctt acctgccagg
     2161 ttaggctccg tagttggggc aggatgatcc tccgggagag ccctttcata tctctgtaat
     2221 tcttt
//
LOCUS       DAJVKX010000256         2065 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.258, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000256 DAJVKX010000000
VERSION     DAJVKX010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2065
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.258"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..423)
                     /locus_tag="OPY25_004495"
     CDS             complement(<1..423)
                     /locus_tag="OPY25_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929920.1"
                     /translation="MRLKVKENITLWRNEGLIAYVALGFLCTFFMEVNALLPYYLQQS
                     IFFETLMSYMAFNTLFSLALSEIFFAMLVVICHNTKLERLTNSILQELHKRIMQGSFI
                     ISFLCFGIFLFCVMAFCIGSLTTNNNYYGKHVINFAYPF"
     gene            complement(497..829)
                     /gene="symE"
                     /locus_tag="OPY25_004496"
     CDS             complement(497..829)
                     /gene="symE"
                     /locus_tag="OPY25_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease SymE"
                     /protein_id="HCS0929921.1"
                     /translation="MTTVHSIADPCDPEVSPTNNRHLTVSYASRYPDYTRIPALTMKG
                     QWLEAAGFATGTEVDVRVMSGCIVLTAQQPQPEESELMQSLRQACKLSARKQKQVQAF
                     ISVMAGSK"
     gene            complement(1057..>2065)
                     /locus_tag="OPY25_004497"
     CDS             complement(1057..>2065)
                     /locus_tag="OPY25_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCS0929922.1"
                     /translation="LSLMSAGNAVQNVNAQKLSTLTVPIPPIAEQKIIAEKLDTLLAQ
                     VDSTKARLEQIPQILKRFRQAVLAAAVSGLLIGSNKRNHHPLCSEWQWPDLPSTWSVH
                     KYSELVDSRLGKMLDKAKNFGSATKYLGNINVRWFSFDLENLQDILISDIERRELSLK
                     LGDVLICEGGEPGRCAIWSEPQDIPVIFQKALHRARVKDKIIPEWLVYNLKNDSNNIS
                     LSQLFTGTTIKHLTGKALANYPIRVPPLEEQHEIVRRVEQLFAWADTIEKQVNNALNR
                     VNSLTQSILAKAFRGELTAQWRAENPSLISGENSAAALLEKIKAERAASGGKKTSRKK
                     A"
BASE COUNT          558 a          425 c          467 g          615 t
ORIGIN      
        1 aaatgggtaa gcaaaattta tgacatgttt cccatagtaa ttattatttg ttgttagcga
       61 accaatacag aatgccatca cacaaaatag aaatattccg aagcataaga aggatataat
      121 gaaagaacct tgcataattc ttttgtgcaa ctcttgcaaa atactatttg tgagcctttc
      181 cagtttagtg ttatgacaaa taactaccaa catcgcaaaa aaaatctcag ataaagcaag
      241 cgaaaataac gtattgaagg ccatgtagct catcagcgtt tcgaaaaata tactttgctg
      301 aagatagtat ggcaatagag cgttgacctc cataaaaaaa gtacatagaa atccaagggc
      361 gacataagca attaagcctt catttctcca aagcgtaatg ttttctttta cttttagccg
      421 catggttttc cttcactcat tgatatgaat tataattaaa gctggcaagg gttctttgcc
      481 agcttatttt atgcgtttac ttagaacctg ccatcacgct gataaacgcc tgcacctgct
      541 tttgcttacg cgccgacagc ttgcacgcct ggcgcagcga ctgcatcaac tcgctttctt
      601 ctggttgcgg ctgctgtgcc gtgagcacaa tacagccgct catcaccctc acatccacct
      661 cggtaccggt ggcgaaaccg gcggcttcca gccactggcc cttcatggtg agggcgggaa
      721 tgcgggtata atccggataa cgactcgcat aactcacggt aaggtgacgg ttatttgttg
      781 gggatacttc tggatcgcac ggatctgcaa tagaatggac ggtagtcatg atggctattc
      841 tcctggaata gtgattgtga tgagcgatat ggccgtgttc ccgcacggcc atatcgcgct
      901 aaatacctgt atataacatc agtaaataaa agaaaagtcc agctgaaaat agactgtaat
      961 gggaatgttc aggaagaaac tggatatatt tttgatggtt atgaatgcgg gggaataata
     1021 aaaagcgcac cgggaaggtg cgcaggaaaa taagcgtcag gcttttttac gcgaggtttt
     1081 tttaccaccg ctggcggcgc gttcggcctt gattttttcc agcagggcgg cggcgctgtt
     1141 ttcaccgctg ataagacttg ggttttccgc acgccactgg gcggtaagct cgccgcggaa
     1201 ggcctttgcc aggattgact gggtgaggct gttgacgcgg ttcagggcgt tgttaacctg
     1261 cttttcaatg gtgtcggccc aggcgaagag ttgttcgacg cggcggacga tttcgtgttg
     1321 ttcttctaat ggaggaactc tgatgggata atttgctagt gcttttcctg taaggtgttt
     1381 aattgtagtt cctgtaaaga gctgagataa gctaatgtta tttgaatcat ttttcaaatt
     1441 ataaactaac cattcgggga tgattttgtc ttttacccgt gctcgatgta atgctttttg
     1501 gaaaataaca ggtatgtcct gaggttcact ccatatagca catcgaccag gttcaccacc
     1561 ttcacatatt aaaacatcgc caagcttgag tgataattct ctgcgctcta tatctgaaat
     1621 tagtatatct tgaaggtttt ctaaatcaaa actaaaccag cgaacattta tatttccaag
     1681 atattttgtt gcagagccaa aatttttagc tttatcaagc attttaccta gtctgctatc
     1741 aacaagttca gagtatttat gaacactcca agttgatggt aggtctggcc attgccattc
     1801 actacataat ggatggtggt ttcttttatt tgaaccaatt aacaacccgc ttaccgcagc
     1861 agctagcacc gcctgacgaa aacgtttcag gatttgtggg atttgctcaa gacgtgcttt
     1921 ggtgctgtct acctgtgcca gcagcgtatc gagtttttcg gcgatgattt tttgttcggc
     1981 tataggtggt attggtactg taagtgttga taacttttga gcattaacat tttgtacagc
     2041 attccctgct gacattaaag acagc
//
LOCUS       DAJVKX010000257         2052 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.259, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000257 DAJVKX010000000
VERSION     DAJVKX010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2052
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.259"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            87..1232
                     /locus_tag="OPY25_004498"
     CDS             87..1232
                     /locus_tag="OPY25_004498"
                     /EC_number="2.4.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylglucosaminyltransferase"
                     /protein_id="HCS0929923.1"
                     /translation="MIKKIIFTVTPIFSIPPRGAAAVETWIYQVAKRLSIPNAIACIK
                     NAGYPEYNKINDNCDIHYIGFSKVYKRLFQKWARLDPLPYSQRILNIRDKVTTQEDSV
                     IVIHNSMKLYRQIRERNPNAKLVMHMHNAFEPELPDTDAKIIVPSQFLKAFYEERLPA
                     AAVSIVPNGFCAETYKRNPQDNLRQQLNIAEDATVLLYAGRISPDKGILLLLQAFKQL
                     RTLRSNIKLVVVGDPYASRKGEKAEYQKKVLDAAKEIGTDCIMAGGQSPDQMHNFYHI
                     ADLVIVPSQVEEAFCMVAVEAMAAGKAVLASKKGGISEFVLDGITGYHLAEPMSSDSI
                     INDINRALADKERHQIAEKAKSLVFSKYSWENVAQRFEEQMKSWFDK"
     gene            complement(1289..>2052)
                     /gene="rfaL"
                     /locus_tag="OPY25_004499"
     CDS             complement(1289..>2052)
                     /gene="rfaL"
                     /locus_tag="OPY25_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen ligase RfaL"
                     /protein_id="HCS0929924.1"
                     /translation="KGIMPFISYAHRHMSDSMVFLFPALLNIWLFRKNSIKLVFLVLS
                     AIYLFFILGTLSRGGWLAVLIVGVLWAILNRQWKLIGVGAILLAIIGALVITQHTNKP
                     DPEHLLYKLQQTDSSYRYTNGTQGTAWILIQENPIKGYGYGNDVYDSVYNKRVVDYPT
                     WTFKESIGPHNTILYIWFSAGILGLASLAYLYGAIIRETASSTFRKVEISPYNAHLLL
                     FLSFVGFYIVRGNFEQVDIAQIGIITGFLLALRNR"
BASE COUNT          638 a          410 c          428 g          576 t
ORIGIN      
        1 tcattatttt gcgttgcttc ggcacgcatt tctttttcta taatatatct tttctataaa
       61 gttaactatt ctggattata gctattatga ttaaaaaaat catatttact gttactccta
      121 tattttcaat tcctcctcgt ggcgcggctg cggtagaaac ctggatttac caggttgcaa
      181 aacgattatc aataccgaat gctattgctt gtataaagaa tgccggctat cctgaatata
      241 ataaaataaa cgataactgt gatattcatt acattgggtt tagtaaagtt tataagcgtc
      301 tttttcagaa atgggctcgt ctcgacccac taccctattc ccagcgcatc cttaatatta
      361 gagataaagt gactacccag gaagatagcg tcattgttat tcataatagt atgaaactgt
      421 atcggcagat cagagagcgc aatccgaatg caaaactggt tatgcacatg cataacgcat
      481 ttgaaccaga acttcctgat acggatgcaa aaattatcgt gcccagtcag tttcttaaag
      541 cgttttatga agaaagattg cccgccgctg ctgttagtat tgtgcctaat ggtttttgtg
      601 ctgagactta taaaagaaac ccacaagata atcttcgtca gcaattaaat attgcggaag
      661 atgccaccgt tctcttatat gccgggagaa tttcgcctga taaaggcatc ctgttgcttt
      721 tgcaggcgtt caaacaatta cgtaccttaa gaagtaatat taaacttgtc gttgttggcg
      781 acccttatgc aagccgcaag ggtgaaaaag cagagtatca aaagaaagta ctggacgccg
      841 caaaagagat tggaactgat tgcattatgg ctggagggca atcacctgac cagatgcata
      901 acttctatca tatagccgat ctggttatcg tgccatctca ggttgaagaa gcattttgca
      961 tggtggctgt agaagcgatg gcagcaggaa aagcggttct tgccagcaaa aaagggggga
     1021 ttagcgaatt tgtgttagat ggcataacgg gctatcacct cgcagaacct atgtcgagcg
     1081 acagtataat taatgatatt aaccgtgcgc ttgctgataa ggaacgccac cagattgccg
     1141 aaaaagcaaa atccctggtg ttttcaaaat acagttggga aaatgtagcg cagcgtttcg
     1201 aggaacaaat gaaaagctgg tttgataagt gattgagtcc tgatgatgga aaacgcgctg
     1261 ataccgtaat aagtatcagc gcgctttttt atctatttct tagcgccagc agaaaaccgg
     1321 taatgatacc aatttgagca atatcgacct gttcaaaatt gccacgaacg atataaaaac
     1381 cgacgaaaga taaaaatagc aagagatgag cattgtaggg gcttatctct actttcctga
     1441 aggtagagct ggctgtttcc ctgatgatag cgccatataa ataggccagg ctcgccagac
     1501 ccaatatgcc tgcactaaac cagatgtaca gaatggtatt atgcggaccg atagattctt
     1561 taaaggtcca cgttggataa tcgacaacgc gtttattata aacactatca tacacatcat
     1621 taccatagcc gtagcccttg atcgggtttt cctgaatcag tatccacgcg gtgccctggg
     1681 ttccgttagt ataacgatat gagctatctg tctgctgtaa tttataaagt aaatgttctg
     1741 ggtctggttt gttagtatgt tgagtgataa ccaaagcgcc gataatggct aataaaatgg
     1801 caccaactcc tattaacttc cattggcgat tcagtattgc ccatagaaca cctactatga
     1861 gcactgccaa ccatccccct cgcgataggg ttcccaggat aaagaaaagg tagatagcgc
     1921 taagcaccaa aaaaaccaac ttaattgaat tttttctaaa caaccaaata ttcaataatg
     1981 ctggaaataa gaaaaccatg gaatcggaca tatgtcgatg cgcatagctt atgaatggca
     2041 taatcccttt at
//
LOCUS       DAJVKX010000258         2021 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.260, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000258 DAJVKX010000000
VERSION     DAJVKX010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.260"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(60..989)
                     /gene="metA"
                     /locus_tag="OPY25_004500"
     CDS             complement(60..989)
                     /gene="metA"
                     /locus_tag="OPY25_004500"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HCS0929925.1"
                     /translation="MPIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDARESRNTPAEHLNNFYCNFDDICDQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAHTLAGEYFRDVEAGLNPEIPYNYFPKNDPQSIPRTT
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            1146..1583
                     /locus_tag="OPY25_004501"
     CDS             1146..1583
                     /locus_tag="OPY25_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCS0929926.1"
                     /translation="MMINIRRSRREEGEKLIAIWRRSVDATHDFLSNAYRAELEELVS
                     DFLPEAPLWVAVTDQDEPVGFMLLTGEHMDALFIDPDVRGQGIGKMLVEHALTLAPGL
                     TTNVNEQNTQAVGFYKKMGFKVTGRSEVDDLGKPYPLLNLIYP"
     gene            complement(1917..>2021)
                     /gene="rrf"
                     /locus_tag="OPY25_004502"
     rRNA            complement(1917..>2021)
                     /gene="rrf"
                     /locus_tag="OPY25_004502"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          520 a          480 c          531 g          490 t
ORIGIN      
        1 cacccgaagg tgcctgattc aacatgctga aacgctttag gattgtcaga agcagaagat
       61 taatccaggg ttggattcat gtgacgcaga tcatatggcg taatctggta gacataatag
      121 ttgagccagt tagtaaacag taaattgccg tggctgcgcc aggttgtgcg cggtatgctt
      181 tgcggatcgt ttttcgggaa atagttgtac ggaatctccg gatttaaccc ggcctcaacg
      241 tcacgaaaat attcccccgc taacgtatga gcgtcatatt caggatgacc ggtgacaaac
      301 gcaatacgtt tatctttgct ggcaaacagg tacgcatccc cttcttctgt ttcggccaga
      361 atttcaagat ccgtataatc ccgtattagc gccgccggga aatcggcata gcgtgagtgt
      421 ggcgcaagaa acgaatcatc aaaaccacgc gttaacagag catgtggatg aagaatgtga
      481 tgttcataga cgccggaaag tttatctgta cgggtctgct tagggatacc ataaagaata
      541 ttgagtgcgg cctgaacggc ccaacagaca aatagcgtcg aagtaacgtg atctttcgcc
      601 cattccagca cctgcctaat ctgcggccag taagccacgt cattaaactc caccagaccc
      661 agcggcgctc cggtcacgat aagcccatca aagttctgat cgcagatatc gtcgaagtta
      721 cagtaaaagt tgttcagatg ctcggctggc gtgttcctcg actcgcgggc atctatccgc
      781 agtagttgaa tatcgacctg caatggcgag ttcgatagca aacgcagaaa ctgattttcc
      841 gtttcaatct tcttcggcat caggttaagg ataagtacct ttagcgggcg aatttcctga
      901 cctgatgcgc gagaagtcgt catgacgaag acattctcct cacgtaaaaa attgacggcg
      961 ggtagctcgt ccagcacgcg aatcggcata acctgataac ctcacgatat acgtttaaac
     1021 gtttagacat ccagatagct gaagatactc agaaatcagg cgaatgtcga gtctgcaagt
     1081 tcaaggtgag aaagtttcac gacagcattt gcattagaat agaagtaagc aaaaaaggag
     1141 tgaagatgat gattaacatt cgtcgttcaa ggcgtgagga aggggaaaaa ctgattgcga
     1201 tctggcgtcg ctcagtcgat gccacgcacg attttctgtc aaacgcttat cgggccgaac
     1261 tggaagaact ggtgagcgat tttctgccag aagcgccact atgggttgcc gtgaccgatc
     1321 aggatgagcc ggtagggttt atgctgctta ccggtgagca tatggatgct ctgtttatcg
     1381 atccggacgt gcgtggtcag ggtatcggta agatgctggt tgaacatgcg ttaacactgg
     1441 cgccgggatt gacaaccaat gttaacgagc aaaatacaca agctgttgga ttttataaga
     1501 aaatgggatt caaggtgacg ggacgttcgg aggtcgacga tcttgggaaa ccgtatccat
     1561 tgttgaattt aatttatccg tgagtagtgg cgctgcctga taagtgcatg caggccggat
     1621 aaggcgaagc cgccatccgg cggtgcaggt tgcctgatgg cgctgcgctt atcaggccta
     1681 catttttatc agttaccaca cacgcaaaaa agcccgtccg tcaggatggg cttcttcact
     1741 tgtctgatgc ctggcagttt atggcgggcg tgctgcccgc caccctacgg gccgttactg
     1801 cgcaacgttc aaatccgctc ccggcggatt tgtcctcctc aggagagtgc tcaccggcag
     1861 accacagata aaacaaaagg cccagtcttt cgactgagcc ttttgcttaa tttgatgcct
     1921 ggcagttccc tactctcgca tggggagacc ccacactacc atcggcgcta cggcgtttca
     1981 cttctgagtt cggcatgggg tcaggtggga ccaccgcgct a
//
LOCUS       DAJVKX010000259         1995 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.261, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000259 DAJVKX010000000
VERSION     DAJVKX010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.261"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            168..563
                     /locus_tag="OPY25_004503"
     CDS             168..563
                     /locus_tag="OPY25_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001731400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HCS0929927.1"
                     /translation="MPRAIWPDKPEDFGALYLAKVFFPDAFYRNQGAPAFGYGELYAD
                     FGLFTPVWLVISGVFKGVLAKYFSNKTQETKSAHYFIMFLFCIGISVIPVSMGWLFPE
                     HLMIAFMVYIASSFVFSEHIRFVLLRNNK"
     gene            complement(886..1092)
                     /locus_tag="OPY25_004504"
     CDS             complement(886..1092)
                     /locus_tag="OPY25_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929928.1"
                     /translation="MDTQLTVNKFIFSLYVILRNKYNPLFTSILVRLNLFHQFRVITG
                     NSGYICFIPFYIDPFRAVRCTYLI"
     gene            complement(1265..1943)
                     /locus_tag="OPY25_004505"
                     /pseudo
     CDS             complement(1265..1943)
                     /locus_tag="OPY25_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079743.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
BASE COUNT          510 a          447 c          440 g          598 t
ORIGIN      
        1 tagcagtcat tgtaacggca ttctttgcat atacgtttac tgatgggaat ccgatagaaa
       61 atatggctaa ttactcggat tatacccgta atgctgttct tgttgcttcc tcaaactttg
      121 actttatgta cggaaaatta ctaatggaga gcgaggttta ctcgaggatt ccgagggcta
      181 tttggcctga taagcctgaa gattttggcg cattgtatct ggcaaaagta tttttccctg
      241 atgcattcta cagaaatcag ggcgctcctg ctttcgggta tggtgaacta tacgcagatt
      301 tcgggctttt tacaccagtt tggttagtta tatctggagt atttaaaggc gtcctagcta
      361 agtatttctc caataaaact caggaaacaa agtcagcgca ttatttcata atgttcctat
      421 tttgcattgg aataagtgtg attcctgtta gcatgggatg gttgttccct gagcatttga
      481 tgattgcttt tatggtatac attgcatctt cctttgtttt ttcagagcat ataagattcg
      541 ttttactaag aaacaataaa taagttatac ggcggcaatg ccgccgtttt atttggctct
      601 gaagcgtaaa aattgttcct gtaaagcttg ttgggtttgc tgagccatca ttaccaacgt
      661 aaattactta tgatatattc atgatagtgc ttgcgtttct agatgatgat ttatgaatag
      721 cccctcaatt atgtatttct cgccgccggt tattattagt cctgccgcta ctccgcccta
      781 atccacatct actcatatgc ggatcatccc gagattgtca ccgtaatata atctaccatt
      841 gataccaata aactctgtgt tatgaatgac agttccctgc ttaagttaga ttaggtacgt
      901 acatcttacg gcgcgaaagg gatcaatgta aaacggtatg aaacatatat atccgctatt
      961 accagtaatg acgcggaact ggtgaaacag gtttaaacga acgagaatgg atgtgaataa
     1021 aggattgtac ttattacgca agatcacata caaagagaaa atgaatttat taacagtgag
     1081 ttgtgtatcc atctagccaa ccattgctaa attggcgcac aaccttcgac acagacgaaa
     1141 atcgctattt tcgtccggca tgatgatggt aacactaaaa aaagggggat tgcatcactc
     1201 tgtagcaaat caagcccctt gacagggttt ctccattatc tttctacgcg ccgtatagcg
     1261 cttctcatcg gcaacctaac ctctgcgcca gactcccctt tgttgttttc acctcgctgg
     1321 ctaccgcttc aggcaagtta gaccacagcg tcagcactgg cttcgtttta tgttcgatag
     1381 cctccacggt aacctgatag tcgcaaaaat tcgccgaacg gggtgtattc tgatccataa
     1441 taaacgcagc gtaatttcct tcactttttg acggcgccgt tccggtgaat aaaaccttct
     1501 agtacccgct gggaatttct accgtcgcat cttctggcaa tgtggcgata tgccgctcaa
     1561 aaaggggggc cggtcactac gtgcactaca gatacatcag cctgtttggc aagttcgcgc
     1621 acccggtttt ccagtgcagc ccatgctccc tggttcaggg cggatttctg cggcgtaata
     1681 ttcgataaat aatttaacga cggccagtcc gaaacgccgc ccaatcctgc caacggcgcc
     1741 tggtgtcccc tgtcgacttt taatagcgta tgggcatttt tataggccga aggggccaac
     1801 gtatccgagg gcggtaaatc ggggtcctgc gcccagttcc gcgggcgacc gcttgcctgg
     1861 ctggtctttg tcacgctata ggcaacccag ttggcaaatt tcgtggcgct attattattg
     1921 agcgtataga catggcgata gattgtttgt tgacttcctc cttgaggaca gccaacgcta
     1981 cagttatcag gttgc
//
LOCUS       DAJVKX010000260         1977 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.262, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000260 DAJVKX010000000
VERSION     DAJVKX010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1977
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.262"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..393
                     /gene="tnpA"
                     /locus_tag="OPY25_004506"
     CDS             <1..393
                     /gene="tnpA"
                     /locus_tag="OPY25_004506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HCS0929929.1"
                     /translation="KYRRQAFYGEKRRAVGSILRKLCEWKNVNILEAECCADHIHMLL
                     EIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTAKIQD
                     YIKHQLEEDKMGEQLSIPYPSSPFTGRK"
     gene            complement(501..839)
                     /gene="maoP"
                     /locus_tag="OPY25_004507"
     CDS             complement(501..839)
                     /gene="maoP"
                     /locus_tag="OPY25_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HCS0929930.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGHAFND
                     LDLGKREPVTEEEKLFVAVCRGEREPVTDAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTEADD"
     gene            946..1794
                     /gene="hdfR"
                     /locus_tag="OPY25_004508"
     CDS             946..1794
                     /gene="hdfR"
                     /locus_tag="OPY25_004508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462788.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HCS0929931.1"
                     /translation="MESTVDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLE
                     NQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASAS
                     LWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEF
                     SSQLLGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAEL
                     ARQQLSALNGCSWLPVNWANEKGGLHTVADSATLSRPLYAIWLQNSDKYSLICDLLKT
                     DVLDEQ"
     gene            complement(1896..1971)
                     /locus_tag="OPY25_004509"
     tRNA            complement(1896..1971)
                     /locus_tag="OPY25_004509"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1936..1938),aa:Trp,seq:cca)
BASE COUNT          558 a          453 c          504 g          462 t
ORIGIN      
        1 aaataccgaa gacaggcgtt ctacggagag aagcgtagag cggtaggcag cattttaagg
       61 aaactatgtg agtggaaaaa tgtgaacatt ctggaagcgg aatgctgtgc agatcatatc
      121 catatgcttc tggagatccc gccgaagatg agcgtgtcag ggtttatggg ttatctgaag
      181 ggaaaaagta gcctgatgct ttatgagcag tttggcgatt tgaaattcaa atacaggaac
      241 agggagttct ggtgcagagg gtactacgtc gatacggtgg gtaagaacac ggcgaagata
      301 caggattaca taaagcacca gcttgaagag gataaaatgg gtgagcagtt atcgatccct
      361 tatcctagca gcccgtttac gggccgtaag taacgaagtt tgatgcaaat gtcagatcgt
      421 atgcgcctgt tagggcgcgg ctggtaagag agccttacag gcgcatcaga aaaacctccg
      481 gctatgccgg aggatattta ttaatcatca gcttcggtgt agtcttctgc gccttcaact
      541 tgcggcttgc cgccagacaa ggtgtggaag cgttttggac gcttgatacg cgtcatatac
      601 ttggaccaga cgcgttctgc atccgttacc ggctcgcgtt caccgcgaca taccgctaca
      661 aacagcttct cttcttcagt cacaggctca cgcttgccaa gatccagatc attaaaggca
      721 tgaccatgac gctcaagcag ttgtgcctct ttaatcgtga aatcaccgtg acgagagaat
      781 ccacgtggat aatgtttatt gtcaaaatat cgattagtcg tcgtaaagct ttccgccatc
      841 ctgcacgctc ctaattcttt gtctgagcta tttatggcgc ggagtattag ttacgcttga
      901 cagagtgtaa aacaaaacat ttaaatcata acgacaaata attttgtgga gagcacagtg
      961 gatacggaat tgttaaaaac tttcctggaa gttagccgga cacgccattt cgggcgggcc
     1021 gcagaagcac tttacctgac gcaatccgcg gtgagctttc gtatcaggca actggagaat
     1081 caactgggcg taaacctttt tacgcggcac agaaacaata tccgtttaac cacggctggc
     1141 gaaaaacttt taccgtatgc ggaaacgctg atgaatacgt ggcaggcggc acgtaaagag
     1201 gtggcgcata cctcacgcca taacgagttt tccatcggcg ccagcgcgtc tttatgggag
     1261 tgtatgctta acgcctggct gggtcgactg taccaactac aggagccgca aagcggcctg
     1321 cagttcgaag ccagaatcgc tcaacggcaa tcgcttgtga agcaacttca tgaacgccag
     1381 cttgatctcc tcattactac cgaagcgccc aaaatggatg agttcagcag tcagctgtta
     1441 gggcacttca ctttggcgtt atattgcagc agccctgccc gtaagaaatc agaactcaat
     1501 tatctgcggc tggagtgggg accagacttc caacagcatg aaacagggct gatcgcagca
     1561 gatgaagtac cggtattaac aaccagctca gccgaactcg cccgacagca gcttagcgca
     1621 ttaaatggct gtagctggct tcctgtaaac tgggcaaatg aaaagggcgg attacatacc
     1681 gttgccgaca gcgcaacgct ttcacggccg ctatacgcca tttggctgca aaacagcgat
     1741 aaatactcgc tgatctgcga tctgttaaaa acggatgtgc tggatgaaca atgaaaatga
     1801 tgaaaagaaa aagaagggaa cttacgatta cctgatcaga taatcaggta atttcaggca
     1861 aaaaaaaatc cttagcagat gctaaggatt atttctggca ggggcggaga gactcgaact
     1921 cccaacaccc ggttttggag accggtgctc taccaattga actacgcccc taattag
//
LOCUS       DAJVKX010000261         1958 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.263, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000261 DAJVKX010000000
VERSION     DAJVKX010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1958
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.263"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            4..1083
                     /gene="waaB"
                     /locus_tag="OPY25_004510"
                     /gene_synonym="rfaB"
     CDS             4..1083
                     /gene="waaB"
                     /locus_tag="OPY25_004510"
                     /gene_synonym="rfaB"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,6-galactosyltransferase"
                     /protein_id="HCS0929932.1"
                     /translation="MKITFVGEAVSGFGGMETVISNVIHTFENSSPKINCEMFFFCRN
                     DKMDKAWLKEIKYAQSFSNIKLSFLRRSKHVYNFSQWLKETSPDIVICIDVISCLYAN
                     KARKKSGKQFTIFSWPHFSLDHKKHAECITYADYHLAISSGIKEQMMARGISEQDISV
                     VYNPVSIKTIIVPPPERDKPAVFLYVGRLKFEGQKRVKDLFDGLARTTGEWQLHIIGD
                     GSDFEKCQAYSRELGIEQRVIWYGWQSAPWQVVQQKIKNVTALLLTSAFEGFPMTLLE
                     AMSYGIPCISSDCMSGPRDMIKPGLNGELYTPGAIDDFVGHLNRVISGEVKYQHDIIP
                     GTIERFYDVLYFKNFNNAIFSKLQK"
     gene            1089..>1958
                     /gene="waaO"
                     /locus_tag="OPY25_004511"
                     /gene_synonym="rfaI"
     CDS             1089..>1958
                     /gene="waaO"
                     /locus_tag="OPY25_004511"
                     /gene_synonym="rfaI"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     3-alpha-galactosyltransferase"
                     /protein_id="HCS0929933.1"
                     /translation="MSRKYFEEEVIQQTLDYNYAQHSDANKFNIAYGIDKNFLFGCGV
                     SIASVLIANREKALAFHVFTDFFGPEDQQRFDALAKQYATQIVVYLIDCERLKSLPST
                     KNWTYATYFRFIIADYFSDKTDRVLYLDADIACKGSIQELIDLNFAENEIAAVVAEGE
                     LEWWTKRSVSLATPGLVSGYFNAGFILINIPLWTAENISKKAIEMLKDPEVVQRITHL
                     DQDVLNILLVNKARFVDKKFNTQFSLNYELKDSVINPVDAETVFVHYIGPTKPWHSWG
                     AYPVSQYFLRAKSN"
BASE COUNT          581 a          332 c          431 g          614 t
ORIGIN      
        1 attatgaaaa taacgtttgt tggcgaagcg gtatctggct tcggagggat ggaaaccgtt
       61 attagcaacg ttatccatac gtttgaaaat agctctccga aaatcaactg tgaaatgttt
      121 ttcttttgtc gtaatgacaa aatggataaa gcatggctaa aagagattaa atatgcgcaa
      181 tcattctcaa atataaaatt aagttttctt cgtcgatcta agcatgttta taattttagt
      241 cagtggctga aagaaacgtc accggatatt gtgatatgta ttgatgtcat ctcatgtctt
      301 tatgccaata aagcacgtaa gaaaagtggt aaacagttta ctattttctc gtggccgcat
      361 ttttcgctcg accataaaaa acatgcagaa tgtataacgt acgcggatta tcatctggcc
      421 atcagtagtg gtattaaaga acagatgatg gcacggggga tctcagagca agatattagc
      481 gtcgtttaca atcctgtctc tattaaaaca atcattgtgc cgccgcctga gcgcgataaa
      541 cccgctgtat ttctctatgt agggcgtctt aaatttgaag ggcagaaaag agttaaagat
      601 ttatttgatg gcttagctcg tacgacaggg gaatggcagc tacatattat tggtgatggc
      661 tcagattttg aaaagtgcca ggcctatagc cgggagcttg gtattgagca gcgtgtgatc
      721 tggtatggtt ggcaaagcgc gccgtggcaa gtcgtacagc aaaaaataaa aaatgttacc
      781 gcgttactac ttacctctgc atttgaggga tttcctatga ctctgctgga agcaatgtca
      841 tatggaattc catgtattag ttctgattgt atgtctggtc cgcgcgatat gattaaaccc
      901 ggtttgaatg gtgagcttta cactccgggt gctatagatg attttgtagg acaccttaat
      961 cgagtcattt ccggtgaagt aaaatatcag catgatatta ttcccggcac gattgagcga
     1021 ttttacgatg tgctatattt taaaaatttt aataatgcga tattctcgaa attacaaaag
     1081 tgatcactat gagcagaaaa tattttgaag aagaagtcat tcaacagact ttagattata
     1141 actatgcaca acatagtgat gctaataaat ttaatatagc ttatgggatt gataaaaact
     1201 ttctttttgg ctgtggtgtc tctattgcat cggttctcat tgctaaccgt gagaaggcgt
     1261 tagctttcca tgtttttacc gatttctttg gccctgaaga tcagcagcga tttgatgcat
     1321 tagcaaaaca gtacgctacg cagattgttg tttatctcat tgactgtgag cgattaaaat
     1381 cgctacccag taccaaaaac tggacctatg caacatactt tagattcatt attgccgact
     1441 atttttcaga taaaacagat agagtgcttt atctggatgc agatattgca tgtaagggaa
     1501 gtattcagga acttattgat cttaatttcg ctgaaaatga gattgcggcg gttgttgctg
     1561 aaggcgagtt ggagtggtgg actaagcgct cggttagcct ggcaacgcct gggttggttt
     1621 ctggctattt taatgccggt tttattttaa ttaacatacc tctttggacc gcagaaaata
     1681 tctctaagaa agcgattgaa atgctaaaag atccggaggt agtacagcgc ataacgcacc
     1741 ttgatcagga tgtattaaat atattgttag tgaataaagc gcgttttgtt gataaaaaat
     1801 ttaatacgca atttagtctt aactatgaat taaaagattc agttattaat ccagttgatg
     1861 ctgagactgt atttgttcat tatatcggac caacgaagcc ctggcatagt tggggggctt
     1921 accccgtgtc acaatatttt ttacgggcta agagcaac
//
LOCUS       DAJVKX010000262         1862 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.264, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000262 DAJVKX010000000
VERSION     DAJVKX010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1862
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.264"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..733
                     /locus_tag="OPY25_004512"
     CDS             <1..733
                     /locus_tag="OPY25_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929934.1"
                     /translation="KYNFSQIDCEVRGLLFVFNHDNQLQHDFYEFFNPPKPAKGRRDK
                     AVNLEKIPLSAGQQIHIIDPFLINYMLAITNDMNDLIAKKEFPDEEYGFYYPQLTFHK
                     VAVTEKYLPATIEVLSSPFMVIKHGAVYKFNRAKGIEEEVYPEGFVVYYNKKGNSDNE
                     FFYLLDILSNYQILDGINKIRIRLAYREKDERILSHFQRGVEKYAHEYGLDEEAKKRL
                     EDLDVKVVSTVKEFFSAEVISWEPK"
     gene            730..1794
                     /locus_tag="OPY25_004513"
     CDS             730..1794
                     /locus_tag="OPY25_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929935.1"
                     /translation="MKNIHSVTDKALYDALNQKQITLNEIQDLFLERGTIICKKTPRK
                     ELARNYSRMTHDYYEHQKIATLLGGQTRTEKITCVRIETGIDKKGIIDAAEKLKKEIT
                     GQDDYCKIIVDGPRVLINIRYLSTNYGKSDFKQAINKEALIEIEPLDDGYSIRRPDNE
                     NLDDYEGLLLGHISAIQNEQADDSNLDLKLNEISLSHNTSADVRTLFFDKLIRTLDGY
                     ELLDVTDAYVYHPKPETIEAEDGNTETGVHVSRASLRGEGVLKSDELSDLYDRGFYIW
                     KIKWKVKENLADPDIFELEAQFGDPLNCTNFSYLVKGVRKYKANGQYFSKPQKLSGRE
                     TERFNKLIENRAYSIIMEIS"
BASE COUNT          649 a          274 c          385 g          554 t
ORIGIN      
        1 aaaatataat ttttctcaaa ttgactgtga agttcgcggt ttactgtttg tttttaatca
       61 tgataatcag ttgcagcatg atttttatga gttttttaat cctcccaaac ccgctaaagg
      121 aagaagagat aaggctgtca acttagaaaa gattccttta tccgcaggtc agcaaattca
      181 tataatcgat ccgtttctga ttaattatat gttggcaata acgaatgata tgaatgattt
      241 gattgccaag aaagagtttc ctgatgaaga atatggattc tattaccctc aattgacttt
      301 tcataaggtt gctgtgactg aaaaatatct tccagctact atagaagtct tgtcatcacc
      361 tttcatggtt atcaaacatg gtgctgttta taaatttaac agagctaaag gtattgagga
      421 ggaagtttat ccagaagggt ttgttgtgta ttacaacaaa aaaggtaaca gcgacaatga
      481 attcttttat ttgttagata ttttgtcaaa ttatcaaatt cttgatggta taaataaaat
      541 taggataagg ctggcatatc gagaaaaaga tgagaggatt ctctcccatt ttcaacgggg
      601 agttgaaaaa tatgcgcatg agtatgggtt agatgaagaa gctaaaaaga ggcttgaaga
      661 tttagacgtt aaagttgtgt ctacagtaaa agaattcttc tctgcagaag ttatttcttg
      721 ggagccgaaa tgaaaaatat tcacagcgta actgataaag ctttgtatga tgctttaaac
      781 caaaagcaaa ttaccctaaa tgaaattcaa gaccttttct tagagagagg aacgattata
      841 tgtaaaaaaa ctcctcgaaa ggaattggca agaaactatt ctcgaatgac tcatgattat
      901 tacgagcatc aaaaaattgc aaccctgcta ggtggccaga caaggaccga aaaaattaca
      961 tgtgtaagaa ttgagactgg tatagataag aaaggtatta tagacgcggc agaaaaactt
     1021 aagaaagaaa ttaccgggca ggatgattat tgtaaaataa tcgtggatgg gccgcgagtt
     1081 ctgattaata ttagatatct ttcaactaat tatggaaaaa gtgatttcaa acaggctatt
     1141 aataaagagg cgttaattga aattgagcct cttgatgatg gttacagtat ccgtcgtcca
     1201 gataatgaaa accttgacga ttacgagggg cttttactgg ggcacatcag cgctattcag
     1261 aacgagcaag cggatgatag taaccttgat ttaaaattaa acgaaatttc actctctcac
     1321 aatacatctg ctgatgttag aactttattc ttcgataaat taatccgtac acttgatggc
     1381 tatgagttac tggatgttac tgatgcttat gtatatcacc ctaagcctga aactatagag
     1441 gctgaagatg gaaacaccga aactggagtg catgtgtcta gggcatcact taggggtgag
     1501 ggggtactta aatctgatga attaagtgat ctttatgata gaggattcta tatctggaaa
     1561 ataaaatgga aggtcaagga gaacttggca gatccagata tatttgagct tgaggcccaa
     1621 tttggtgatc ctctcaattg tactaatttc tcatatttag ttaagggagt cagaaaatat
     1681 aaggcaaacg gacaatattt cagtaagccg caaaaactct ctggtagaga aactgagcga
     1741 ttcaataaat taattgaaaa tagagcttat tctattataa tggaaatcag ctaatacatc
     1801 ataaggagtg gctatgtcac aattaagatt gaagtggatg agattgaaaa tcaggaccag
     1861 cc
//
LOCUS       DAJVKX010000263         1804 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.265, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000263 DAJVKX010000000
VERSION     DAJVKX010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1804
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.265"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..341
                     /locus_tag="OPY25_004514"
     CDS             <1..341
                     /locus_tag="OPY25_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0929936.1"
                     /translation="NKLPDLRGEFIRGWDDGRGIDAARALLSIQNGMLEKHRHIVVAN
                     DGYDTKDEWELATIFKKTYTQGRGLDATNTGGSLIPSPTLHSRGSIGNTGGSETRPRN
                     IAFNYIVRAA"
     gene            complement(348..965)
                     /locus_tag="OPY25_004515"
     CDS             complement(348..965)
                     /locus_tag="OPY25_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCS0929937.1"
                     /translation="MNNAAAVLDQNGIAITAGDITVYNYDAENREYLSATVEYLAYGV
                     GIPAHSCIDAPPEKRPGFAVCRDTDQNIWKYVPDHRGETVYSTENGNAVQITQPGDYP
                     PDTTVKQPATIYDVWDGETWVTDAGRQHAAELEAAGAHRQQLEEQAMASVELINLKLR
                     AGRRLTPQETEKLNAVLDFIDVLNATDISTAPDINWPEMPLAAAS"
     gene            complement(965..1468)
                     /locus_tag="OPY25_004516"
     CDS             complement(965..1468)
                     /locus_tag="OPY25_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001802272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCS0929938.1"
                     /translation="MGEGSALPVGVPVPWPSATPPAGWLKCNGAAFSSEMYPKLAKAY
                     PTNKLPDLRGEFIRGWDDGRGIDSGRSLLNAQSHSVIDHIHYMELWTGEGLAANSTRA
                     GTNPGILATYGDGGIVKTDESGVKVPSSLRAIGTRGVYRLGANGGNTGTENRPRNIAF
                     NYIVRAT"
     gene            complement(1479..1772)
                     /locus_tag="OPY25_004517"
     CDS             complement(1479..1772)
                     /locus_tag="OPY25_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCS0929939.1"
                     /translation="MRGWDDGRGIDAGREILSFQEGTIVSGFDDNDTGDISSLSSTQY
                     GFGDTLSSNQWGAINGKKWIFDASSKGAQKYDWWAYVSARPRNIAFNYIVRAA"
BASE COUNT          463 a          445 c          411 g          485 t
ORIGIN      
        1 cgaataaatt accggattta cggggtgagt ttattcgtgg ctgggatgat gggcgaggaa
       61 ttgatgcggc acgcgcttta ttgagcattc aaaacgggat gttggaaaaa caccgccata
      121 ttgttgtagc taacgatgga tatgacacaa aagatgaatg ggagttggcc acgattttca
      181 aaaaaacata tacacaaggc agggggcttg atgccacaaa tacaggaggg agtttgattc
      241 catcaccaac gcttcattca cgaggaagta ttggtaacac aggtggtagt gaaacccgcc
      301 cccgcaatat tgcatttaac tatatcgtga gggcggctta gttatattca actggctgct
      361 gccagaggca tttccggcca gttgatatcc ggtgcagtgc tgatgtcagt cgcattaagc
      421 acatctatga aatcaagcac ggcgtttagt ttttccgtct cctggggcgt caatcggcgt
      481 ccggctcgta gtttgagatt tataagctca acagatgcca ttgcctgttc ctcaagttgc
      541 tgacgatgcg ctccggcagc ttccagttct gctgcgtgct gtcgtcccgc atctgtcacc
      601 caggtctcac catcccagac atcatagata gtagctggct gtttcaccgt cgtatcagga
      661 gggtaatctc ccggttgtgt gatttgcaca gcgttaccat tctctgtgct gtaaaccgtt
      721 tcgcctctgt ggtctggaac atatttccag atgttctggt cggtatcacg acagacagcg
      781 aagccggggc gtttttctgg tggcgcgtca atgcatgagt gagccggaat tccaacacca
      841 taagcgagat actcaacagt ggcagagaga tattcacggt tttcagcatc gtagttataa
      901 acggtaatat cgcctgcagt tatagcgata ccattctgat caagtactgc agcagcatta
      961 ttcattaagt agcccttaca atatagttaa acgcaatatt acgggggcgg ttttccgttc
     1021 ctgtattccc tccgttggca cctaatctat aaacaccacg agtgccaata gcacgtagtg
     1081 aagatggaac ttttacacct gactcatctg ttttaacaat cccgccatca ccgtatgtag
     1141 ccagtatacc agggtttgtt cctgcacggg tgctatttgc ggcaagccct tcaccagtcc
     1201 ataactccat atagtgaata tgatctataa ccgaatgtga ttgtgcatta agcaaggaac
     1261 gccctgaatc aattccccgc ccgtcatccc agccacgaat aaactcaccc cgtaaatccg
     1321 gtaatttatt cgtggggtaa gcctttgcca gtttggggta catttcagaa gaaaatgctg
     1381 ctccgttaca tttcagccac cctgctggcg gtgtggctga gggccacgga acaggtacac
     1441 caacgggcag tgcagagcct tcccccaaac caacgtttct atgccgctct tacgatgtaa
     1501 ttaaatgcaa tattacgcgg acgagctgat acataagccc accagtcata tttttgtgca
     1561 cctttactgg atgcatcaaa tatccacttt ttgccattta tggcccccca ttgattagag
     1621 cttaaagtgt caccaaatcc gtattgtgtt gagctgagtg aactgatatc cccagtatca
     1681 ttatcatcaa aaccggagac gatagtgcct tcctgaaatg aaagtatctc tcgtcctgca
     1741 tcaatacctc gtccgtcatc ccagccacga ataaactcac cccgtaaatc cggtaattta
     1801 ttcg
//
LOCUS       DAJVKX010000264         1779 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.266, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000264 DAJVKX010000000
VERSION     DAJVKX010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1779
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.266"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            341..781
                     /locus_tag="OPY25_004518"
     CDS             341..781
                     /locus_tag="OPY25_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCS0929940.1"
                     /translation="MQKYIFSADKNAFFPVELKIAYQESGEWPDDGIEIDDTVAAEFM
                     KEAPEGKYRGVIDGMPAWIDIPPPTHEEQIAAAELEKQQLINQVNEYINSKQWPGKAA
                     IGRLKGEELAQYNLWLDYLDALELVDTSGAPDIEWPTPPAVQAR"
     gene            complement(753..1346)
                     /locus_tag="OPY25_004519"
     CDS             complement(753..1346)
                     /locus_tag="OPY25_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCS0929941.1"
                     /translation="MKPVFDENGLATVPGDMRCYYYDAVTSEYTGWSDEYINTGVSMP
                     ACSTGIDPGEYIPGRVAVFTGKGWSHEEDHRNETVYSTENGAAVTVDYIGAIKDGYVT
                     LSPLTPYDKWDGEKWVTDTEAQHSAAVEAAEAQRQSLIDAAMASISLIQLKLQAGRKL
                     TQPENTRLNAVLDYIDAVTATDTSTAPDVIWPELPEA"
     gene            complement(1346..>1779)
                     /locus_tag="OPY25_004520"
     CDS             complement(1346..>1779)
                     /locus_tag="OPY25_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCS0929942.1"
                     /translation="VPVPWPSATPPTGWLKCNGAAFSAEEYPELAKVYPTNKLPDLRG
                     EFIRGWDDGRGVDAGRQLLSSQGDAIRNIEGFADGGIGMSFDAIRGAFYDAGTRSARM
                     PNNTTDIGKTDDLGFDASRVVPTANENRPRNIAFNYIVRAA"
BASE COUNT          459 a          442 c          411 g          467 t
ORIGIN      
        1 aacggaatgt gggcacagga gataatcaga taccggatat gggagcattc gcttctggtt
       61 cgggatggtt caggctacca ggtggatata ttgttcagtt tggcactttt tcaggaaaca
      121 cgacccgctt tatcagtgga cacttcccta taccattccc taatcagccg atggtttcag
      181 tcagtgttat gtctgataac gttcagtcag acccgtcgat tcctgctccg caggttttgt
      241 ctgtaaattt tgaacatatc agtaattcag cgtggcgtgt ggcaaccagt gatatctcac
      301 agcaatacag attcagttat atttcgatag gacggtagaa atgcagaaat atattttcag
      361 cgccgataaa aatgcgtttt tccctgtgga gcttaaaatc gcttatcagg aatccggcga
      421 atggcccgat gatggaatcg aaattgacga cactgttgcc gccgaattta tgaaggaagc
      481 accagaagga aaatacagag gtgtcatcga cggaatgcct gcatggattg atattccacc
      541 gccaactcat gaggaacaaa ttgccgcagc cgaactggaa aagcagcaat tgattaatca
      601 ggtcaacgaa tacataaaca gtaagcaatg gcctggtaaa gcggcgattg gtcgcctgaa
      661 aggtgaggaa ctggcgcaat ataatttgtg gctggattat ctggacgcac tggaactggt
      721 cgatacttcc ggtgcgccag atattgaatg gcctacgcct ccggcagttc aggccagatg
      781 acgtccggcg ctgtgctggt atctgttgcc gttaccgcgt caatataatc cagcacagcg
      841 ttaagtcggg tgttttctgg ctgcgtcagc ttccgcccgg cctgtaattt cagttgaatc
      901 agactgatgg aagccattgc agcatcaatc agcgactggc gctgtgcttc tgcagcttct
      961 actgcggcgc tatgctgtgc ctcggtatcc gtcacccatt tctcaccatc ccatttatcg
     1021 tatggcgtta acggtgaaag cgtgacataa ccgtctttga tggcaccgat ataatccact
     1081 gtaacagctg cgccattttc agttgagtaa acggtctcat tgcgatggtc ttcttcatgg
     1141 ctccatccct tacccgtaaa tactgccact cttcccggaa tgtattcgcc cgggtcaata
     1201 ccagtggaac aagcgggcat acttacgcca gtattaatat attcatcaga ccagcccgta
     1261 tattcagacg ttactgcatc ataataataa caacgcatat cacccggcac tgtagccagc
     1321 ccattttcat caaaaacagg tttcattatg cagccctcac aatataatta aaggcgatgt
     1381 tacgtggacg gttttcatta gctgttggca cgacacgaga ggcgtcgaat ccaaggtcat
     1441 cggttttgcc tatatcagtt gtgttattcg gcattctcgc agatcgtgtt cctgcatcat
     1501 aaaaagcccc tctgattgca tcaaaagaca taccgatccc gccatctgcg aatccctcaa
     1561 tatttcttat tgcatccccc tgtgaagata ataattgtcg cccggcatcc actccacgtc
     1621 cgtcatccca gccacgaata aattcaccgc gtaaatcagg caatttattt gtcgggtaaa
     1681 cctttgccag ttccgggtat tcttcagcag aaaaagccgc accattgcat ttcagccagc
     1741 ctgttggcgg agtggcggaa ggccacggaa caggcacac
//
LOCUS       DAJVKX010000265         1778 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.267, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000265 DAJVKX010000000
VERSION     DAJVKX010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1778
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.267"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(632..1336)
                     /locus_tag="OPY25_004521"
                     /pseudo
     CDS             complement(632..1336)
                     /locus_tag="OPY25_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611456.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS481 family transposase"
     gene            1389..1694
                     /locus_tag="OPY25_004522"
     CDS             1389..1694
                     /locus_tag="OPY25_004522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system SymE family toxin"
                     /protein_id="HCS0929943.1"
                     /translation="MARLCGILTYSRVERLSVRLYGEWMPQAGFINGMPVKVRVMRDC
                     IVITPQHTRGLFVCIEGMGVTFINQKKVKAWLKTFPGALNDTGDIPVIKRSRLEGGI"
BASE COUNT          482 a          410 c          397 g          489 t
ORIGIN      
        1 ttaccaattc aaacaagtaa tgtcataaaa atctatatat cagagcacct cttaatctga
       61 aaaaaattgc gttattgcca atataaccag cattgatgtt aacatcgtat tgtcagggtg
      121 gaatagaatg ccagtcaaaa agcaattata ccttccattt acattcaagt gataacatta
      181 caatgaaacc caccacactg ggtgtgggaa acttatcttc gaagagagga taattatcag
      241 gcatcgttgc aacattgttt atatttaaac atacatctcc taactcgacg gtaagattat
      301 tagttaactt ttcctcgcag ggaagatctt taatggaaaa tcttgttttc cgaaacggaa
      361 aagcaattat aacgctccaa cgagagtctc aacactaaga gctgactgac acaggccaga
      421 ctgattatac aggcatgaaa aagctctccc cttcctttca gttcttgctg gattatgcaa
      481 acgtcgcacc acctccccgt gaacatggca cattaatttg aagcaactct catccggtat
      541 cgcttttcag tgcagcgaaa ttcatcgcag gtgcccctgt aaatagaccc gttttagttc
      601 catgcatttt taagattccg gccagataac gttattggcg gtattcctcc ggtatcatat
      661 tgttccgcga ttcatgtgga cgttcgcagt tatattctga taacccttta tccgtaattt
      721 cccgcacctc attcagcgtt ctgaacagat aagaattgag tatttctgta cggtatgtcc
      781 ggttaaaacg ctcgatgaaa acgtttttct tcggcttacc cggctggata aacgccagct
      841 ttactacatg tttctttgcc cattcagcca gtgccagcga gataaattcc ggtcccttat
      901 ccatacgcag catggccgga taaccgaggt tgctgtaatc ctgtcgagta cacggaccac
      961 tcgcagagct ggcagattca gatcgatttc aatcgacaac gcttcacgat tacagtcatc
     1021 aacaacattg aacgtgcgaa aacgacgccc ataaaccagc tctggttcag cgcttccggc
     1081 gtgaccagtg gcgagggatt gcgtaccggc agccgttgtt tacccttacg gcgaaaattc
     1141 agcttgagca gacagtaaat acggtggagc cttttgtgat tccacgcgta tccctgccgc
     1201 cgtatccaga cctccagtta tccctggtgg cttcagaaat accggcctcc cggtagacat
     1261 ctttaacagt ccgtccggat tcgactgatc taatcacaac gatgatctgg tgcgcagtaa
     1321 tacgggcttt acgcatagcg atctcctgcg ttggcagatt gattatgtcg gatgatctct
     1381 aaatgtgaat ggctcgatta tgcgggatac ttacatactc acgcgttgag agactttcag
     1441 ttcgtttgta cggtgaatgg atgccgcagg cggggtttat taacgggatg cccgtcaagg
     1501 tgcgggtaat gagggattgc atcgtgatca cgccgcagca tacccgcgga ctctttgtct
     1561 gtattgaagg gatgggcgtg acttttatta atcaaaagaa ggtgaaagcg tggctaaaaa
     1621 cctttccggg ggcgctgaac gataccgggg atattccggt gattaagcgg agcaggctcg
     1681 aaggcgggat ttgacagggg gttaaataat aaaaaagccg ggaagagtta atttctttcc
     1741 cggctttatt aacacctaat gtattactgg tatctatt
//
LOCUS       DAJVKX010000266         1750 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.268, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000266 DAJVKX010000000
VERSION     DAJVKX010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1750
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.268"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..556
                     /locus_tag="OPY25_004523"
     CDS             <1..556
                     /locus_tag="OPY25_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CDP-paratose synthase"
                     /protein_id="HCS0929944.1"
                     /translation="SLDAVFINCGTSLPPNTSLYAYTKQKANELAAAIIDKVCGKYIE
                     LKLEHFYGAFDGDDKFTSMVIRRCLSNQPVKLTSGLQQRDFLYIKDLLTAFDCIISNV
                     NNFPKFHSIEVGSGEAISIREYVDTVKNITKSNSIIEFGVVKERVNELMYSCADIAEL
                     EKIGWKREFSLVDALTEIIEEEGK"
     gene            553..1569
                     /locus_tag="OPY25_004524"
     CDS             553..1569
                     /locus_tag="OPY25_004524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-paratose 2-epimerase"
                     /protein_id="HCS0929945.1"
                     /translation="MKLLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHW
                     LSSLGNFEFVHGDIRNKNDVTRLITKYMPDSCFHLAGQVAMTTSIDNPCMDFEINVGG
                     TLNLLEAVRQYNSNCNIIYSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDF
                     HSPYGCSKGAADQYMLDYARIFGLNTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEI
                     KNGINKPFTISGNGKQVRDVLHAEDMISLYFTALANVSKIRGNAFNIGGTIVNSLSLL
                     ELFKLLEDYCNIDMRFTNLPVRESDQRVFVADIKKITNAIDWSPKVSAKDGVQKMYDW
                     TSSI"
BASE COUNT          581 a          240 c          363 g          566 t
ORIGIN      
        1 atcacttgat gcagtattca taaattgtgg aacatcactg ccaccaaata cgagtttata
       61 tgcatatact aaacaaaaag caaatgaact cgccgccgcc attatagata aagtttgcgg
      121 taaatatata gagttaaaat tggagcattt ctatggagct tttgatggag acgataagtt
      181 taccagtatg gttattagac gttgtttaag taaccagcca gtaaagttaa catctggttt
      241 gcaacagaga gatttcttgt atataaaaga tctactaaca gcgttcgatt gtattataag
      301 taatgttaat aatttcccca aatttcatag tattgaagtt ggtagtggag aggcgatatc
      361 aattcgtgaa tatgtagata ctgttaaaaa tatcacaaaa agcaattcta taattgaatt
      421 tggcgtggtc aaagaaagag taaatgaatt gatgtatagt tgtgctgata tagcagaact
      481 tgaaaaaata ggatggaaaa gagagttctc tcttgttgat gcattaactg aaataattga
      541 agaggaaggg aaatgaagct tttaattacc ggtggatgtg gcttccttgg gagtaatctt
      601 gcctcctttg ctttaagtca agggattgat ttaattgtat tcgataatct atcacgtaaa
      661 ggtgcaacag ataatttaca ttggttatcc tccttaggaa actttgagtt tgtacatggt
      721 gatattcgca acaaaaatga tgttacaaga ttaataacta agtatatgcc tgatagctgt
      781 tttcatcttg caggtcaagt ggcaatgact acatctattg acaatccttg tatggatttt
      841 gaaattaatg taggtggaac tttaaattta cttgaggcag tacggcagta taattcaaat
      901 tgtaatataa tttattcatc aacaaataaa gtatacggcg atcttgagca atataaatac
      961 aatgaaacag aaactagata cacttgtgta gataagccta atggatatga tgagagcaca
     1021 caattagatt tccactcacc atatggttgt tcaaaaggtg ctgcagacca atacatgctt
     1081 gattatgcaa ggatttttgg tttgaataca gtggtgttca ggcattcatc aatgtatggt
     1141 gggagacagt ttgctactta tgatcaaggc tgggtaggtt ggttttgtca aaaagcggtt
     1201 gaaattaaaa atggtattaa taaacccttc actatttctg gtaatggtaa gcaagttagg
     1261 gatgttttgc atgctgaaga tatgatttcg ttatatttca ctgccttggc aaatgtatca
     1321 aaaattaggg ggaacgcttt taatattggt ggtaccattg tcaacagcct atcattactt
     1381 gaattattca aattgcttga agattattgc aacatagata tgaggttcac taatttacct
     1441 gtaagggaaa gtgatcagcg tgtttttgtt gcagatatta aaaaaatcac taatgcaatt
     1501 gactggagcc cgaaagtctc ggcaaaagat ggtgtccaga aaatgtatga ttggactagt
     1561 tctatatgat gtttctgccc gcgaaagcgg gcataattaa agaatgaaat attttttata
     1621 attaaaagat gaagctgacg tgaggaaact gaggttggtt agaattccaa gacatcttat
     1681 tattgccgct tcctcttggc tttcaaagat aataattgcc ggtgttcagt tagtaagtgt
     1741 taaatttctt
//
LOCUS       DAJVKX010000267         1745 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.269, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000267 DAJVKX010000000
VERSION     DAJVKX010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1745
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.269"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..182)
                     /locus_tag="OPY25_004525"
     CDS             complement(<1..182)
                     /locus_tag="OPY25_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929946.1"
                     /translation="MKKLTMRECESINPTLLLAIKILISALDEKTKIRLREHIEKTEQ
                     EIASSIHDSIMTETFL"
     gene            complement(193..834)
                     /locus_tag="OPY25_004526"
     CDS             complement(193..834)
                     /locus_tag="OPY25_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929947.1"
                     /translation="MINSLSEQLPLKTIGIVLTDDYYTYLGIASLFEDGKCFMFPLNG
                     EYNSCQISASEDIIIIIDGRVLIQGVWKGFKALMQHYPHARRIWLTRRDIGKLYPHGC
                     DRDPDIDPDLAKPVFIEHFIKYACANDVAVGEIAPLTKKEEELLWHFLYKKSMSQIAS
                     SYGISRKTLYIHRLRICRKYGFKRFFHLLFIYQRSRHIFASKICRVDKNADQA"
     gene            complement(980..1504)
                     /locus_tag="OPY25_004527"
     CDS             complement(980..1504)
                     /locus_tag="OPY25_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HCS0929948.1"
                     /translation="MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSD
                     SKDLRGFNFKYRYEFNETWGMLGSFTATRNEMENYTWKEGKLHKNGSDSVDYGSLMFG
                     PTYRFNDYVSLYGNAGIATMKFNKHSKEESFAYGAGVIFNPVKSISIDASWEASRFFA
                     VDTNTFGVSVGYRF"
BASE COUNT          526 a          377 c          306 g          536 t
ORIGIN      
        1 tgaagaaaag tctctgtcat gatgctatca tgtatgcttg aggctatttc ttgttcagtt
       61 ttttcaatat gctctctgag ccttattttt gttttttcgt caagcgccga gataagtatc
      121 ttaatggcaa gcagcaaagt aggattgatg ctttcacact ctctcatcgt taactttttc
      181 atcttgttta cttcaagcct gatcggcgtt tttgtctaca cggcaaattt tagatgcgaa
      241 gatatggcga cttctttggt aaataaatag caaatggaaa aagcgcttga agccatattt
      301 acgacagata cgcaatctat gaatgtacaa agtcttacga ctaatgccat agctactggc
      361 gatctgactc atcgactttt tatataaaaa gtgccataac aactcttcct ccttttttgt
      421 caacggcgca atttcaccga ccgctacatc gtttgcacaa gcgtatttaa tgaaatgctc
      481 aataaaaaca ggctttgcca aatcgggatc gatatcagga tctctatcgc agccatgtgg
      541 ataaagtttt ccaatatctc tgcgcgtgag ccagattcga cgagcatgtg gataatgctg
      601 catgagcgcc ttaaaacctt tccagacccc ctgaatcaaa actcgtccat caataataat
      661 tatgatatct tcgctagctg atatctgaca cgaattatat tctccattaa gtgggaacat
      721 aaagcacttc ccatcctcaa agagtgaagc gatgcctaaa taagtataat aatcatccgt
      781 taaaactata cctatcgttt ttaacggaag ttgttccgat agtgaattta taataatttc
      841 atcaatagaa taacgctacg gtgagtgttt tatcttcctc ttaagattac ctgactgatt
      901 ataaccatcc ctactctgta gcaacgccat attatatttt tagttccttg ccataaacgt
      961 aacgcttata cttttaatat cagaagcgat aacctacgct gacaccaaat gtattggtat
     1021 ccacagcgaa gaaacggctt gcttcccatg atgcatcgat agatatactc ttaacaggat
     1081 taaatattac accagcgccg taggcaaagg actcttcttt tgagtgttta ttaaatttca
     1141 tcgtcgctat acccgcattg ccgtacaggc tcacatagtc attaaagcga tatgttggtc
     1201 caaacatcaa agaaccatag tccacagaat cggaaccatt tttatgcaat ttcccctctt
     1261 tccaggtgta gttctccatt tcattgcgcg tcgcagtgaa tgagcctaac atcccccagg
     1321 tctcattgaa ctcgtaacga tatttaaaat taaagcctcg cagatctttg ctatcgctat
     1381 ttttcaatga actgagatga gtttgtgcat aaccaaacga tacggtgtgc tgatcgttag
     1441 ccaaagctaa aggtgacgct aataataaac ctaaaaaaac aaggaacgaa gaccgtcttt
     1501 tcattaaaac cactccattt ttgatatata attaaggcgg taccggaact tatggcacac
     1561 aaatagcatt tagattaaga gcacctaatg cgcttattac cagtcatgcc aactgcggag
     1621 gtaatataac ctgatatatt cgataatgga tatgaaatca gtcttacaga gttcttactt
     1681 ttttattaat agcggattca tagttgcttc agacccgatc ctggcatcgc atccgtcagg
     1741 cggac
//
LOCUS       DAJVKX010000268         1724 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.270, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000268 DAJVKX010000000
VERSION     DAJVKX010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1724
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.270"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            40..357
                     /locus_tag="OPY25_004528"
     CDS             40..357
                     /locus_tag="OPY25_004528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HCS0929949.1"
                     /translation="MPTAARLNDKGTQYDDYYETVSIADSPTVFIDGLSVARMGDAVD
                     CGGMVNMTRMKSGKASKVRKVDRVGKQGFELHHIDEVVNRGDVYNVDNPRVNTILTYT
                     GDL"
     gene            354..620
                     /locus_tag="OPY25_004529"
     CDS             354..620
                     /locus_tag="OPY25_004529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCS0929950.1"
                     /translation="MKLKENISDYTESEFIDFLRVIFSENESDTDETLDPLLEYFEKI
                     TEYPGGTDLIYYPETESDGTPEGILNIIKEWRESQGLPCFKKSK"
     gene            863..1141
                     /locus_tag="OPY25_004530"
     CDS             863..1141
                     /locus_tag="OPY25_004530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001729069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCS0929951.1"
                     /translation="MELKNNLEDYTEDEFIEFLNNFFEPPEELTGDELSKFIDNLLRH
                     FNKITQHPDGGDLIFYPSEEREDSPEGVIEELKRWRKSQRLPCFKENK"
BASE COUNT          564 a          272 c          415 g          473 t
ORIGIN      
        1 ctcacaactt attatttagt aatgaagcta tggagaaaaa tgcccacagc cgcccgactc
       61 aacgataaag gcacccagta cgacgattat tacgagaccg tgagtatagc ggattccccc
      121 acggtattta ttgacggcct gtccgttgcc agaatgggtg atgcggtgga ctgtggcggg
      181 atggttaata tgactcgaat gaaatcaggt aaggcatcaa aggttagaaa agttgacaga
      241 gtcggaaaac aggggttcga gcttcatcat atagatgaag ttgtaaatag aggcgatgtt
      301 tacaatgtag acaatccccg tgtgaacacc atattgacat acacaggcga tttatgaaat
      361 taaaagaaaa tattagtgat tatacggaaa gtgagttcat tgatttcttg agagtgatat
      421 tttctgaaaa cgagtcggat acagatgaaa cattagatcc attacttgag tattttgaga
      481 agatcactga atacccaggt ggaacagatc ttatctatta tcctgaaacg gaaagtgatg
      541 gaacacctga gggtattctg aacataatta aagaatggag agaatctcaa ggattgcctt
      601 gttttaagaa aagtaaatga aaatcaggtg taggggaatg cccagagtta ctggcgcagt
      661 ttagtaaatc gaatcaaact ttgataaaaa gaggtcgagc gccttactcc ttgataaggc
      721 aacaagtcgg aggtaggtgg acttatgaaa ttccccacgt tggaaagatc cagtatggag
      781 gaatggtgtt tgatgttgat aaccttatga taaacactcc taaaaatcat atacgattgc
      841 ataagtaagg tttgaggtga aaatggaact aaaaaataac cttgaagatt atacagaaga
      901 tgagtttatc gagtttttaa ataatttttt tgagcctcct gaagagttga ctggagatga
      961 attatcgaag tttattgata atcttctacg ccattttaat aaaattactc aacaccctga
     1021 tggcggggat ttgatatttt atccatcaga ggaacgagaa gatagtcctg aaggagttat
     1081 tgaagagcta aaacgctggc ggaagtctca gagactcccc tgttttaagg aaaataagta
     1141 gcgatcagtg gtgaggagtt tgtcaaccgg aaccgggatg ataatgcagt gaccgttaaa
     1201 aggcaaaaat atgtcagtta agggagtaac tatcaaaggc ataattctga gtgtttttac
     1261 actgaaccgt agtgccagag gatatattta tctgacgcga atcgtatgaa gtgatagctt
     1321 tacgtacggt ttgtgagagg ctgtagggaa agatcctacg gcctactcac taagagtcta
     1381 tttttgtaca ttgtttcatg ttctggaaac acgataaagt atgagcctga cgaactctcg
     1441 cccgctaaag ttccacgctg gaacctgacg gccaggagtc ggacatcttt gcggtggcga
     1501 atttacatcc gttcaaaaaa atctaatgta agagatagat gatatggcta aatatatatt
     1561 cctctttatc tggattgtga cattttctgt cagcgctggt gagcgaggat attatttatt
     1621 cgtatggggt aaccctgaag ggaaggaata ttttaaagaa tatagagctg atgaaaggat
     1681 atatgcggtc aataaatcct gttggaatga aagagcgggg aact
//
LOCUS       DAJVKX010000269         1692 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.271, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000269 DAJVKX010000000
VERSION     DAJVKX010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1692
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.271"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..311
                     /locus_tag="OPY25_004531"
                     /pseudo
     CDS             1..311
                     /locus_tag="OPY25_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683846.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            371..1357
                     /locus_tag="OPY25_004532"
     CDS             371..1357
                     /locus_tag="OPY25_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001636847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase"
                     /protein_id="HCS0929952.1"
                     /translation="MTETECSERCVDFLKETMFNYNSGEITLAALDNDHLTPSEAGSN
                     GIYEAFEHRLIDFLTTPATPATASGDESGAIDQTDTSQPAAIEAFINSPEFQKNIRMR
                     DIEKNKIGSGSYGTVYRLHDDFVVKIPINERGIKVDVNSPEHRNCHPDRVSKYLNMAN
                     DDKNFSRSASMNINGKDVTVLVSKYIQGQEFDIEDEDNYRMAEALLESRGVYMHDIDN
                     VGNILIKEGVLFFVDGDQIVLSQESRQQRSVSLATRQLEEQIKARYLVKLKQSETEGN
                     TEDIEYYKSLITELDELIGEEEQAPAPGRRFKLAAPEEGTLVAKVLKDELKK"
BASE COUNT          513 a          314 c          397 g          468 t
ORIGIN      
        1 tcatagttgc cagatatcag aaagacattt aagagatatc attgatcata aaagagagca
       61 tgttttttca acgtatgaga agttcataga ttttttcagg aatatattta ccagtcgaag
      121 tttaatctct gattatagag aaatctataa tctactgtgc caaaaaaacg agcgtccaga
      181 tattacgaag cctttctcgc tacgaccatt ttcgaagcga gatgaagact gtacacgatg
      241 gcgccccctt cttggatata ttaaacttat tgatgcctcc aggcctgaaa caagagataa
      301 atacactgta gaggtattag cacatcaaga aaatatgtta ctactacaga tgttttatga
      361 tggaatgtta gtgaccgaga cggagtgctc tgagcgttgc gtcgattttt taaaagaaac
      421 gatgtttaat tataattccg gggaaattac gcttgccgct ttagataatg atcacctgac
      481 gccgagcgaa gcaggtagta atgggatcta tgaggctttt gagcatcgtt tgatagactt
      541 cctgaccacg cccgccacgc ccgccacggc gtctggtgat gagagcggcg ctattgatca
      601 gacagataca tcacaaccag cggcaataga ggcgtttatt aactcgccgg agtttcagaa
      661 aaatattcgc atgcgtgata ttgaaaaaaa taaaataggt agcggaagtt atgggacagt
      721 ctatcggtta catgatgact ttgttgttaa gattccaatt aatgagcggg gaataaaagt
      781 ggatgttaac tctccggagc atcgtaattg tcatcctgat cgtgtcagta agtatttgaa
      841 tatggccaat gacgacaaga atttttctcg ttcggcctcc atgaatatta atggtaaaga
      901 cgttacagtt ttagtttcaa aatatattca aggtcaggag ttcgatattg aagatgaaga
      961 taactatcga atggcggagg cgcttcttga atcccggggg gtttatatgc atgatataga
     1021 taacgtaggt aatattctga ttaaagaggg ggtacttttc tttgtcgatg gcgatcaaat
     1081 cgtgctgtca caagaatccc ggcaacagcg aagcgtttct cttgcaacaa ggcaactgga
     1141 agagcaaatt aaggcccgtt acctggtaaa attaaagcag tccgagaccg aaggaaatac
     1201 tgaagatatt gaatattata agtcacttat tacagaactt gatgagttaa tcggagagga
     1261 agaacaggca cctgcgccag gaagacgttt taaactagcc gcgccggagg aagggactct
     1321 tgtggctaag gtattaaagg atgaattaaa aaaatagcat ttagttccgt tcttttctgc
     1381 gaatcgccgg gggcacattc gctacagatt taccaatcaa ttattgagag ttgctattcg
     1441 cttaaaggtc gttcggggga tctggacagc ctgtagcgga gatgcaactc gccactaggg
     1501 ttggcgatgc cgcgctgcca tagtgggtga aatgccacgc gatggtgcaa cactattaac
     1561 tcgccttgat ttttcccctc ttcctgacaa gaaaaacctg gctttacgga tggtctcatg
     1621 ccgtcgtatt agcgttgttc ggcgtagtat gtaaatttac ttatagcaat agaagaacat
     1681 tctcaaaaca ta
//
LOCUS       DAJVKX010000270         1656 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.272, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000270 DAJVKX010000000
VERSION     DAJVKX010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.272"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(127..>1656)
                     /gene="sefC"
                     /locus_tag="OPY25_004533"
     CDS             complement(127..>1656)
                     /gene="sefC"
                     /locus_tag="OPY25_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEF14/SEF18 fimbria usher protein SefC"
                     /protein_id="HCS0929953.1"
                     /translation="VLDVSIYEKNGQVQNYTVPYSTPVLSLPDGYSKYSVTIGRYREV
                     NNDYIDPVFFEGTYIYGLPYGFTLFGGVQWANIYNSYAIGASKDIGEYGALSFDWKTS
                     VSKTDTSNENGHAYGIRYNKNIAQTNTEVSLASHYYYSKNYRTFSEAIHSSEHDEFYD
                     KNKKSTTSMLLSQALGSLGSVNLSYNYDKYWKHEGKKSIIASYGKNLNGVSLSLSYTK
                     STSKISEENEDLFSFLLSVPLQKLTNHEMYATYQNSSSSKHDMNHDLGITGVAFDSQL
                     TWQARGQIEDKSKNQKATFLNASWRGTYGEIGANYSHNEINRDIGMNVSGGVIAHSSG
                     ITFGQSISDTAALVEAKGVSGAKVLGLPGVRTDFRGYTISSYLTPYMNNFISIDPTTL
                     PINTDIRQTDIQVVPTEGAIVKAVYKTSVGTNALIRITRTNGKPLALSTVLSLKNNDG
                     VIQSTSIVGEDGQAYVSGLSGVQKLIASWGNKPSDTCTVFYSLPDKNKGQISFLNGVC
                     K"
BASE COUNT          528 a          326 c          248 g          554 t
ORIGIN      
        1 aaaaaacagc ctcatttatt ttaatcatta atttaagttc ttgtgcttta atagttgagc
       61 tgaaaaaacc agtaacaatc agaaaaacag agacaatgaa cttaggtatt gacgaattat
      121 actgattcat ttgcacactc catttaaaaa gctaatctga cctttgtttt tatcgggaag
      181 agagtaaaaa actgtacaag tatcggaggg cttattcccc cacgaagcga ttaatttttg
      241 cactcctgac aatccagata catatgcctg accatcttcg ccaacaatag atgttgattg
      301 gattactcca tcattattct taagtgaaag aactgtgcta agagctagtg gctttccatt
      361 tgttcttgta attctaatta atgcattagt acccacgctt gttttatata cagcttttac
      421 aatagcacct tcggtaggaa ctacttgaat atcagtttgc ctaatatccg tatttattgg
      481 taacgttgtt ggatctatag atatgaagtt attcatatat ggagtaagat aactggatat
      541 tgtatagcct ctaaaatcgg ttctaacacc tggtaggccc agaacttttg ccccacttac
      601 acctttagcc tcgaccagtg cagcagtatc cgatatactc tgaccaaacg taattcctga
      661 tgaatgagca atcaccccac cagaaacatt catcccaata tcacgattta tttcattatg
      721 actatagttt gctccgatct ccccataagt acctcgccaa gaagcattta aaaatgtagc
      781 cttttgattt ttcgatttat cttctatttg ccctcttgct tgccatgtca attggctatc
      841 aaatgccaca ccagtaatac ctaaatcatg attcatatca tgctttgaag aggatgagtt
      901 ttgatatgta gcatacattt catgatttgt aagtttttgc aaaggtacac tgagtagaaa
      961 actgaataaa tcttcatttt cttcactaat ctttgatgta cttttcgtat atgaaagcga
     1021 taacgaaaca ccatttaaat tcttcccata actagcaatt attgattttt taccttcatg
     1081 tttccaatat ttatcataat tgtagcttaa gttaacagaa cccagagatc ctaatgcctg
     1141 acttaataac atagaggttg ttgatttctt atttttatcg taaaattcat catgctcgct
     1201 actatgaatt gcttcagaaa aagttctata atttttcgaa taatagtaat gactagccaa
     1261 agatacttcg gtgtttgtct gagcgatatt tttattgtat ctaatcccat atgcatgacc
     1321 attttcattg gatgtatcag tcttcgaaac agatgttttc cagtcaaaag acagagcacc
     1381 atactcacca atatctttac ttgcgcctat ggcgtatgaa ttataaatat ttgcccattg
     1441 cactccacca aataaagtaa acccataagg cagaccatat atataagtcc cttcaaaaaa
     1501 aacaggatcg atataatcat tgttaacctc cctgtatcta ccaatagtta cactatattt
     1561 agaatatcca tcaggcaaag ataatacagg agttgaatat ggcactgtat agttttggac
     1621 ctgcccattt ttttcataaa tgctaacatc aagaac
//
LOCUS       DAJVKX010000271         1648 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.273, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000271 DAJVKX010000000
VERSION     DAJVKX010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.273"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            287..823
                     /locus_tag="OPY25_004534"
     CDS             287..823
                     /locus_tag="OPY25_004534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HCS0929954.1"
                     /translation="MNKMLLAGSAGIVLLSAAASPVWADDNASTFSLGYAQSHTNHAG
                     TLRGVRLANNYEMSPDWGLTTSFAWLNGSQRYSDESSNGRVTTRYYSLLAGPSWKINN
                     QLSLYSQVGPVLLHQRDHGINESDSKVGYGYSAGVAYTPVSNVAITLGYEGADFDATH
                     NSGSLNSNGFNLGVGYRF"
     gene            870..1502
                     /locus_tag="OPY25_004535"
     CDS             870..1502
                     /locus_tag="OPY25_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HCS0929955.1"
                     /translation="MKSHIMPGVALMVILFSGNLMAATNMTDNVTLNNDKISGQAWQA
                     MRDIGMSRFELFNGRTQKAEQLAAQAEKLLNDDSTDWNLYVKSDKKAPVEGDHYIRIN
                     SSITVAEDYLPAGQKNDAINKANQKMKEGDKKGTIEALKLAGVSVIENQELIPLQQTR
                     KDVTTALSLMNEGKYYQAGLLLKSAQDGIVVDSQSVQESPTHPVQHDAAH"
BASE COUNT          476 a          338 c          381 g          453 t
ORIGIN      
        1 gggactcact cccttgccgc ctttcagcaa ctcaaattat ttttggtata tatcagtgaa
       61 cttctatttt tgtcagtttt tatttttcag tttatttatt attaaatact gtttctggcc
      121 tggatatatt ttcgtgaata gcctcccgat agccggagat aaaggtattt gctggcgtaa
      181 cagtgctcat aatttaaaag atttatttat agtttgttat cacggaaaga ttttaactta
      241 atacatgcca gtaaggcatc aggtaaaaat aaccggagag aagaagatga acaaaatgct
      301 attagccgga agtgccggta ttgttctgct gtctgctgca gccagtccgg tatgggcaga
      361 cgataatgcc agtacatttt cacttggata cgcccagtcc catactaatc acgccgggac
      421 gttgcgtggg gttcggctgg caaacaacta tgaaatgtca ccggactggg ggctgacaac
      481 ctcatttgcc tggctaaatg gaagccagcg ctattccgat gaaagcagta atggtcgtgt
      541 aacaacccgt tattactccc tgcttgcagg cccctcatgg aaaataaata accagttaag
      601 tctgtatagt caagtgggcc ccgtattatt gcatcagcgt gatcacggga taaatgagtc
      661 tgatagtaag gtcggatatg gttattctgc tggcgtggct tataccccgg tcagtaatgt
      721 cgctataact ctgggttatg agggagcgga ttttgatgct acccataaca gcggaagcct
      781 taatagcaat ggttttaatc ttggcgtggg ttaccggttc tgaataggat aatccgataa
      841 aaaatgttac tttgtggaga tgatggatta tgaaaagcca tattatgcca ggcgttgcgc
      901 tgatggttat cctgttttca ggaaatctta tggccgcaac aaacatgact gataacgtta
      961 ctctgaataa tgacaagata tccggacagg cctggcaggc catgcgtgat atcggaatgt
     1021 cgcgattcga gttgtttaat ggtcgcaccc aaaaggcgga acaactggct gcgcaagcag
     1081 aaaaactcct gaacgatgac agcactgact ggaatctgta tgtcaaatca gataaaaaag
     1141 ccccagttga aggagaccac tatattcgga taaattcatc gattacggta gccgaagatt
     1201 atctccctgc gggccagaaa aatgatgcta ttaataaagc aaaccagaaa atgaaagaag
     1261 gagataaaaa agggactata gaggccctga aactagcagg cgtcagtgtt attgaaaatc
     1321 aggaactcat tcctcttcag caaacccgta aggatgtgac tacagcgctt tccttgatga
     1381 acgaaggaaa atactatcag gcaggtctgt tactgaaatc agctcaggat ggcatagttg
     1441 tagactctca gtcagttcag gaatcaccca cgcaccccgt gcagcacgac gccgcgcatt
     1501 aatatccccc agcctgctgt atatattaca gcaggcagca ttatgtctga cagccattac
     1561 cagtttgttc tttgctgtcg gcattgtttt taaaattcat ccgtgaagtt caggaatatc
     1621 agggtacctg catttatatc tattgtga
//
LOCUS       DAJVKX010000272         1617 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.274, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000272 DAJVKX010000000
VERSION     DAJVKX010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.274"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(154..>1617)
                     /locus_tag="OPY25_004536"
     CDS             complement(154..>1617)
                     /locus_tag="OPY25_004536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HCS0929956.1"
                     /translation="FSVLIRLLFLTDRYLWCDEASSVLISRHSVDNLLFHAAFDVHPP
                     LYYLLLHDWIILLGDSIAAVRSLSLLFGILTVVLVIALTRWLANERTALLAGWFAALM
                     PMAVHYSQETRMYALMGMLTLAAALALMMWIKTPTHNRYLVAYALLMTFSFYTHYFTL
                     FTLIAHWIAVTILSCQSHKTACYLKLPGWWFANLAIAVAYLPWLPVLFNLLTHLAQLR
                     AGNDIGWIPPVTWRDLPAMYWHFFTGNNGQGFPSFILWLAVGGFIGTVGRISLYNGEY
                     ERYQLILFCNLVIPVMLVFIISWWMPLFIDRYFFFSSLSIPPLLAVLLTRAKKAVCGF
                     WFILFTLLFGYGSYHNNPEHIDEFKPLVNYINTRHQPNDAVVVSKMFDYLSYVYYNKR
                     DYRTFLYTPPNAHGTSGRPNAYGFGSLFYAQADQTYIDTLTTLSKSYHRVWLVSGGNF
                     SQDYPLPSEWQNIAKFRSGRFQVQLFVIPTQQARQMQ"
BASE COUNT          498 a          344 c          378 g          397 t
ORIGIN      
        1 tttaaatgtt acgctgagat agccatcttt atttaatatc acctacctgg aggcgatatg
       61 attgaggttt ttgaagcgtt tggctggacc ttacttttag gcggtctggc agtggcagta
      121 ctgtttatca ctgcactgga tagaaaacgg taatcattgc atttgacgcg cctgttgagt
      181 tggtattaca aataattgta cctgaaatct accacttctg aattttgcga tattttgcca
      241 ttctgacggc aaggggtaat cctgactgaa gttaccgccg cttaccaacc agacacgatg
      301 gtaacttttt gaaagcgttg tcagagtatc aatatatgtc tgatcggctt gcgcataaaa
      361 cagtgaacca aagccatagg cattcggtct tcctgatgtt ccgtgtgcgt taggtggtgt
      421 ataaagaaac gtacgataat ctcgcttatt ataatacaca taacttaaat aatcgaacat
      481 tttactgact accacggcat cattaggctg gtgacgggta ttaatatagt ttaccagtgg
      541 tttaaactcg tctatgtgct cagggttatt atgatatgaa ccatagccga ataataaggt
      601 gaataagata aaccagaagc cacaaaccgc tttttttgcg cgggtaagta ataccgcgag
      661 caggggagga atgctcagcg atgagaagaa gaaataacga tcgataaata acggcatcca
      721 ccaggaaatg atgaagacca gcattacagg gatgaccaga ttacaaaata atatcagctg
      781 atatctttca tattctccgt tgtataaaga tattcgcccc acagtaccga taaaacctcc
      841 cacagccagc cacagaatga acgacggaaa accctgtccg ttgtttccgg taaaaaaatg
      901 ccagtacatc gcaggcaggt cacgccatgt tacgggggga atccaaccga tatcattacc
      961 ggctctcaac tgcgccagat gagtcagtaa attaaacaat acgggcaacc aggggagata
     1021 agcgacagca atcgccaggt tagcaaacca ccagccagga agtttaaggt agcaggccgt
     1081 tttatggctt tggcaggata atattgttac tgcgatccag tgggcaataa gtgtaaatag
     1141 ggtgaaataa tgggtgtaaa agctgaacgt cataagtaaa gcatacgcga caagatagcg
     1201 attatgggtg ggtgttttta tccacatcat caatgctaac gcggcagcga gcgttagcat
     1261 tcccattaac gcgtacatgc gcgtttcttg actgtaatga actgccatcg gcatcagggc
     1321 ggcgaaccat cccgccaata aggctgtacg ttcatttgcc agccatcgcg taagcgcgat
     1381 aaccagcaca actgtcagga tcccaaagag tagactgaga gagcgtaccg ctgcaatgct
     1441 atcacccaat aatatgatcc agtcatgcag taacagataa taaagcgggg gatgcacgtc
     1501 aaaagcggca tggaagagca gattatctac gctatgtcga ctaatcagca cgctggacgc
     1561 ttcgtcacac caaaggtagc ggtcagttaa aaacagcaac cgtataagga cggagaa
//
LOCUS       DAJVKX010000273         1593 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.275, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000273 DAJVKX010000000
VERSION     DAJVKX010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1593
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.275"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..129
                     /locus_tag="OPY25_004537"
     CDS             <1..129
                     /locus_tag="OPY25_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein CI"
                     /protein_id="HCS0929957.1"
                     /translation="RDITRLPGGRIFVEGGNRAFECKIEDIEIIGKIISLTVKYVK"
     gene            145..336
                     /locus_tag="OPY25_004538"
     CDS             145..336
                     /locus_tag="OPY25_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929958.1"
                     /translation="MLGKVFFVVLSCSLLLNPLTTYARNYPCSGKKGGVSHCTSDGKF
                     VCNDGTISKSKKICTKNSR"
     gene            525..1577
                     /locus_tag="OPY25_004539"
     CDS             525..1577
                     /locus_tag="OPY25_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCS0929959.1"
                     /translation="MAVRKLTTGKWLCECYPAGRSGRRVRKQFATKGEALAFERHTME
                     ETESKPWLGESVDRRTLKDVVELWFKLHGKSLTAGQHVYDKLLLMVDALGNPLATDLT
                     SKMFAHYRDKRLTGEIYFSEKWKKGASPVTINLEQSYLSSVFSELSRLGEWSYPNPLE
                     NMRKFTIAEKEMAWLTHEQIVELLADCKRQDPILALVVKICLSTGARWREAVNLTRSQ
                     VTKYRITFVRTKGKKNRSIPISKELYEEIMALDGFNFFTDCYFQFLSVMEKTSIVLPR
                     GQLTHVLRHTFAAHFMMSGGNILALQKILGHHDIKMTMRYAHLAPDHLETALRFNPLA
                     TLPSGDKVAAAVGITP"
BASE COUNT          478 a          348 c          362 g          405 t
ORIGIN      
        1 cgtgacatta ctcgtttacc cggtggaaga atcttcgtcg agggtggaaa cagagccttc
       61 gaatgtaaga tagaagacat tgaaataatt ggtaaaatta taagtttaac agtcaagtat
      121 gttaaatagt accgggagga aactatgctt ggtaaggtat tttttgtggt tttgtcatgt
      181 tctttgttat taaacccact aactacctat gctagaaatt atccctgctc agggaaaaag
      241 ggaggtgttt ctcactgtac ctcagatggc aaattcgttt gcaatgatgg aactattagt
      301 aaatccaaaa aaatctgtac taaaaactca cgataacttt tgcttttata tctgcgtcta
      361 aaataaaaat gagccgcagg ttaaccgcaa aagttacatg ctcacatagc aaaaagaata
      421 gccaacttca ttatggcttc agtgagatgt atggtcgtag gatttcatac attgacactg
      481 gttatacata cagtaaaaat gctctctact ggagggcatt ttttatggca gtacgaaaac
      541 tcaccacagg gaaatggctt tgcgaatgtt accccgccgg acgaagtggg cgtcgtgtgc
      601 gtaaacaatt cgccaccaaa ggcgaagctc tggcttttga gcgtcacact atggaagaaa
      661 ccgaatcaaa gccatggctg ggcgaatcag tggatcgtcg aaccctgaaa gacgtggttg
      721 agctatggtt caaactacat ggtaaatctc tgactgctgg gcaacatgtc tatgacaaat
      781 tgctgctgat ggttgacgct ctgggcaatc ctcttgcaac cgatctcacc tctaaaatgt
      841 ttgcccacta tcgagataaa cgcctgacag gcgagatcta cttcagcgag aaatggaaga
      901 aaggagcaag cccggtcacc attaacctgg agcaaagcta tctaagtagt gtttttagcg
      961 aactatcccg tctgggcgaa tggtcgtatc cgaacccact ggagaacatg cgaaaattca
     1021 ccatcgcaga aaaagagatg gcatggctta cccatgagca gattgttgaa ttactggctg
     1081 attgcaaacg tcaggaccca attctagcac tggtagttaa gatatgctta agcacaggcg
     1141 cacgctggcg agaagccgta aatcttactc gttcacaggt gaccaaatac cgaattacct
     1201 ttgtaagaac gaaggggaag aaaaacagaa gcatccctat cagtaaagag ctttacgaag
     1261 agatcatggc gcttgatggg ttcaatttct tcacagactg ctattttcaa tttttatccg
     1321 tgatggaaaa aacgtctatc gtgctccctc gcggtcaact cacacacgtt ctgcgccata
     1381 cgtttgcggc gcacttcatg atgtcgggtg gaaacattct ggccttacaa aaaattctcg
     1441 gacaccacga tataaaaatg actatgcgtt acgcacatct ggcaccggat catctggaaa
     1501 cggcgctccg tttcaatcct ctggcaacgc tgccaagtgg cgacaaagtg gcggcagcgg
     1561 ttggcattac cccgtaataa ccaccactga cca
//
LOCUS       DAJVKX010000274         1558 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.276, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000274 DAJVKX010000000
VERSION     DAJVKX010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.276"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            295..798
                     /locus_tag="OPY25_004540"
     CDS             295..798
                     /locus_tag="OPY25_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HCS0929960.1"
                     /translation="MAAVGMVQKLNTPMNLEFYASNLYLHLSEWCSEHSLTGTATFLR
                     TQAQGNVTQMMRMFNFMKNAGATPIVKAIDVPGEELCSLEELFQKTLEDYQQRASTLS
                     RLADEAKALNDASTLDFLHTLEKEQQQDGVLLQTILEEVRSAKRAGLCLAQTDQHLLN
                     VVTYQHH"
     gene            1129..1464
                     /locus_tag="OPY25_004541"
     CDS             1129..1464
                     /locus_tag="OPY25_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCS0929961.1"
                     /translation="MKPLIFTLSLLALTGCTITRQAQVSEASPISGIVRLTYNQPLFF
                     TSRTDDYVSHGTATRECQQMGYADAVSFGQPVGTCSIYAGSLCLNTRFTLSWQCRGVS
                     VPQIMPLYY"
BASE COUNT          431 a          378 c          346 g          403 t
ORIGIN      
        1 atctttcaaa tagttataag aatgacatac caaaaatcat ttctgatgaa aaaatcacac
       61 agctgaaaat gtaaaaaaag ataaacaatt gcatttaagg attttcttat tttcattgac
      121 gcgctattct cattaccgat cgataaacag gaaatgagat cgcataaggg actggcggaa
      181 cggagttctt ctgctaagag tatttattgt gcatagaggt aagaatgtga caacgatccg
      241 ttgcattctc gtctgtcatg cacatcaaca ctttctggaa ataaggatat tgttatggca
      301 gctgtaggaa tggttcaaaa gctcaacacg ccaatgaatc ttgagtttta cgcatcaaat
      361 ctttacctcc atctaagcga atggtgttct gaacacagtt taacaggtac agccaccttt
      421 cttcgtaccc aagcgcaagg caacgtgacg caaatgatgc gcatgtttaa ttttatgaaa
      481 aacgccggcg ccacccctat cgttaaagcc attgacgttc cgggtgaaga gctctgctct
      541 ctggaagaat tgttccagaa aaccctggag gattatcagc aacgcgccag cacgctgtcg
      601 cgtctggcag atgaagcgaa agcgctgaat gatgcctcaa cgctcgattt tctccatacc
      661 ctggaaaaag agcagcagca ggatggcgta cttttacaaa ctattctcga agaagttcgc
      721 agcgctaaac gagcagggct atgcctggcg caaaccgatc agcatctcct taacgtcgtg
      781 acctatcagc atcactgata gcggcacccc gagcgacaat attgagacgt tattagccgg
      841 atagcaacgc gaagcagctt atccggccta caccgtttct ggtctgtttg ccagaggtgg
      901 cgcctgcata aatcatgacg ttttgcctac actacacatt tacgaacaca cattcaaatt
      961 taatgaaaca aagtttcatt aaatgaaaag acgctcacac attttctgtt cccgctgtaa
     1021 atcccctgcc gttaccttta atcaaggcga atccgtaagt tattccagcc attgacggtg
     1081 caagacacga ggtagcatgg tctgataccg aactgtcgga gcgattttat gaagcctctt
     1141 atttttactc tttcactgct agccctgacg ggatgcacca ttactcgaca agcgcaggtc
     1201 agcgaagcca gcccgataag cggcatcgtg cgcctgacgt ataaccagcc gctatttttt
     1261 acttcacgga cagatgacta tgtatctcac ggaaccgcaa cacgcgaatg ccagcagatg
     1321 ggctatgccg atgccgtttc gtttggtcag ccggtaggaa cctgtagcat ttatgcgggc
     1381 tcgttgtgtc tgaacacccg atttaccctc tcctggcagt gccggggcgt ttccgtcccg
     1441 caaatcatgc cgctttatta ttaaggcggc tggcttaacg ccgacaccat gtacaataga
     1501 ggagagtgca gggtcgctat tgccagcatg aaggtgctgg ctttccttta tttttata
//
LOCUS       DAJVKX010000275         1539 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.277, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000275 DAJVKX010000000
VERSION     DAJVKX010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.277"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            42..1037
                     /locus_tag="OPY25_004542"
     CDS             42..1037
                     /locus_tag="OPY25_004542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0929962.1"
                     /translation="MRPIKNAKKIDYNLIKVFDTVITEGNATRAARKLDVTPAAISQA
                     LLRLQNLYGEELFIRTRKGLVPSSKGKSLHQVFRQAIESIESTLCDKTDAQESNELIV
                     LGSDITENYYFPALLDTVLMNRYIIKHYAIKKTGEYSPASMLTHGYADIIMGILEIKN
                     EMIESFLIDNLSDFVCVCGEKSPLVGLEKMSLYNFYAARHAVYHSDMFSSFNADSIDL
                     FKSSTPYAGRREIGYYSDSLFGVIGVVEKSDMVAILPGKIATYFRDVRRYNIKILRMP
                     DEIIFRTLPVYAYLATNSTHYKNAKKLISTFQSTFLFSQEKQPDALVEGSTSLCD"
     gene            complement(1054..1490)
                     /locus_tag="OPY25_004543"
                     /pseudo
     CDS             complement(1054..1490)
                     /locus_tag="OPY25_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459036.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
BASE COUNT          462 a          260 c          310 g          507 t
ORIGIN      
        1 ttaaatgatg gtgccagatt ataccagcca ggataaccta tatgcggcca ataaaaaatg
       61 ctaaaaaaat tgactacaat ctgatcaaag tgttcgatac ggttattact gaaggaaatg
      121 caaccagggc tgcgaggaaa ctggatgtca cgcctgcggc gatctctcag gctcttcttc
      181 gtttacaaaa tctttatggc gaagagttat ttatcagaac ccgcaaagga ttagtcccgt
      241 ccagcaaagg taaatcgctt caccaggtat ttcgccaggc aattgaatct atagaaagca
      301 cactgtgcga taaaacagat gcgcaggaga gtaatgaact cattgttctg ggaagtgata
      361 tcactgaaaa ttactatttt ccggcattgc tggatactgt gttgatgaat cgatatatta
      421 ttaaacacta tgcgattaaa aaaacagggg aatactcgcc agcctccatg ctgacgcatg
      481 gctatgcgga tatcatcatg ggaattctgg aaattaagaa tgagatgatc gaaagttttc
      541 ttattgataa tttatctgat tttgtttgtg tttgtggtga aaaaagtcca ttggttgggc
      601 ttgaaaaaat gtctttatat aatttttatg ctgccagaca tgctgtctat cattcagata
      661 tgttctcttc tttcaatgct gatagcattg atttattcaa gagcagtacg ccttatgcgg
      721 ggcgcaggga aataggttat tatagtgatt cactatttgg cgttatcggt gttgttgaaa
      781 aaagcgatat ggttgcgatt ttgccaggaa aaattgctac ttattttaga gatgtgcggc
      841 gttataatat aaaaatacta cgtatgcctg atgaaataat ttttcgtaca ttacccgttt
      901 atgcttatct ggctacaaat agcacccatt ataaaaatgc caaaaaactg atatcaacat
      961 ttcagtcgac ctttcttttt agccaggaaa aacagcctga cgctttggtt gaaggaagca
     1021 catccttatg cgattgatct gtttaatatc aaattactgt attaaataaa taaccattat
     1081 gaccatggtc agtaaagcaa aaaataatgc tatatattta tccccttctt tttttaaaga
     1141 agaggggagg tttttgtttt cattgctgat aataatgttg gcatctactt taatacccgt
     1201 tcgaggcacc gtggaaaaaa ctggctcaag ccaaagcctt taaggtcgcg ccgcagtaga
     1261 tataaaatct gggtcaggtt ggcgtcgctg ataaattgac ttctttcccc ccaaagttca
     1321 ttagtgagtt gttttttata aataatctct tgttgtgcat gattcagcat atattccaga
     1381 cactttatgc gcattgcggc aatttttatt atctttcccg tttttatgtt ttttagctca
     1441 ttggtcttat cattgtaagt gtgcgtgctg ttaattaaat aaatagtcat gatgttattt
     1501 aatgggttta attggggtag cgataataat atgcatatt
//
LOCUS       DAJVKX010000276         1462 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.278, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000276 DAJVKX010000000
VERSION     DAJVKX010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1462
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.278"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..487)
                     /locus_tag="OPY25_004544"
     CDS             complement(<1..487)
                     /locus_tag="OPY25_004544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCS0929963.1"
                     /translation="MMRKPSQIVHCISCDLSCQLFPDSAVRVQYCHNAAFSIWPDGNA
                     FLKKGFIEKLLLDRHNHLSSGFIFVDFSFPNLRRFTDLQWADSLANSGMHIVLISDRS
                     LTPLANYWILKSNKIQGIIYSDDDDIVQQQKMHRLFTGRLANSKRGRTLNYTEFILLK
                     HF"
     gene            complement(1217..1354)
                     /locus_tag="OPY25_004545"
     CDS             complement(1217..1354)
                     /locus_tag="OPY25_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001454271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929964.1"
                     /translation="MRKARLTEHQNIAVIKLVEAGRAVKDICQEADISEVTDDIYGHW
                     V"
BASE COUNT          457 a          291 c          270 g          444 t
ORIGIN      
        1 caaagtgctt cagtaatata aattccgtat agttaagcgt tcgtccacgt ttactgttgg
       61 caagccgacc ggtaaacaag cggtgcatct tttgctgttg cacaatatca tcgtcatcgg
      121 aataaataat tccttgtatt ttattgcttt tcaaaatcca gtaattggcc agcggagtta
      181 aacttctgtc agaaatcagg acaatatgca taccactgtt tgccagactg tcagcccatt
      241 gtaaatcggt aaatcgtcga agattcggga aagaaaaatc aacaaagata aaaccgctgg
      301 ataaatggtt gtgtctatca agcaataact tttcaataaa cccttttttc aggaaagcat
      361 taccatctgg ccagatggaa aatgccgcat tatgacagta ttgcacccgt actgcgctgt
      421 cagggaataa ttgacaggat aaatcgcaac taatgcaatg gacaatttgt gaaggctttc
      481 tcatcatcct gaacgactcc cgtcgatgtt tctattaata tttcattggt aaataaatgt
      541 gtcaatccag ataatataca gtgctacggc tgtcaaaagt cgcgaattat tgtcagtgtc
      601 ataaactcct ggaaagacct aaaatacagc tttaaggaac catgacagat ccgacagtcg
      661 taatacatca tttcggattc gtatttcacc cattgagatt tttatacata atctccaata
      721 tcataaaaaa tcttaaaaca gcactatttg ctaaattatg aggatgataa ataacggttc
      781 tcaataccat ctgtctgctg ccctcgtcac tatcggggtg atgtgatgaa atataaaagt
      841 aaatcctgtc aacctgtaat gaattcttat tattaaaacc taatttaaga ttttttcttt
      901 tattgcattg ttattcaatg acttaatggt gaaatttgtg ctctcatcaa cttcttatat
      961 acaaatttaa gactatttta tagagacgca tgtaaacttt aagggggtgt aatgctaatg
     1021 ccatgggaaa atcttgtaac ttaacgccgg gagtcatacc ttgccaataa gttgatctga
     1081 cttaattctg aacgtgacag tgtgagcaac cgacagactt atcggtcgaa gcaacttcag
     1141 cttctggctt ctcttttcaa ttgctcattt gatgaaaact ctttcccgga gcacattagt
     1201 gagaaacagg atgtggtcaa acccaatgtc catagatgtc gtcagtcact tcagaaatat
     1261 ccgcctcctg gcagatatct ttaaccgctc gtccagcttc gaccaactta attacggcga
     1321 tgttctgatg ctcagtgaga cgggctttac gcatagagat tccttcgtca gcagatcgat
     1381 gacgtgatct ctaaatgtga atagcacgat tatgtgggat acgtacaaaa aattaaacta
     1441 actgccagta atatgagtac tt
//
LOCUS       DAJVKX010000277         1444 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.279, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000277 DAJVKX010000000
VERSION     DAJVKX010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1444
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.279"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(95..775)
                     /gene="pipA"
                     /locus_tag="OPY25_004546"
     CDS             complement(95..775)
                     /gene="pipA"
                     /locus_tag="OPY25_004546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector protease
                     PipA"
                     /protein_id="HCS0929965.1"
                     /translation="MLPVTYRLIPQSGVSTYGLNTADTPVFPDIPEHAPNPSRLRLAH
                     DSLAINSEFRLEPECVVEYLISGAGGIDPDTEIDDDTYDECYDELSSVLQNAYTQSET
                     FRRLMNYAYEKELHDVEQRWLPGAGEAFETTVAQEHFKLSEGRKVICLNLDDSDDSYT
                     EHYESNEGRQLFDTKRSFTHEVVHALTHLQDKEENHPRGPVVEYTNIILKEMGHPSPP
                     RMVYIFNK"
     gene            complement(998..>1444)
                     /gene="pipB"
                     /locus_tag="OPY25_004547"
     CDS             complement(998..>1444)
                     /gene="pipB"
                     /locus_tag="OPY25_004547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector PipB"
                     /protein_id="HCS0929966.1"
                     /translation="PDSLITEDGFLNLRGVNLAHKDFQGEDLSDIDASNADFRETNLS
                     NVNLVGANLCCANLHAVNLMGSNMTKANLTHADLTCANMSGVNLTAAILFGSDLTDTK
                     LNGAKLDKIALTLAKALTGADLTGSQHTPTPLPDYNDKTLFPHPIF"
BASE COUNT          385 a          267 c          322 g          470 t
ORIGIN      
        1 gggcgcttag aatatagtta gaaaatactg ctagaacatt tcccgaaaaa acggactacg
       61 tgggttttta gtttcttttc gtttcttgat gtgtctattt attgaagatg tagaccattc
      121 tgggaggtga aggatgcccc atctctttca gaataatgtt ggtatattcg acaacagggc
      181 ctcttggatg attttcttct ttatcctgaa gatgggtcag tgcatgtaca acttcatgag
      241 taaatgaacg ttttgtgtca aaaagttgtc ttccttcgtt actttcataa tgttcggtat
      301 atgaatcatc agaatcgtcc agattgagac aaataacttt cctgccttct gaaagtttga
      361 agtgttcctg agccacggta gtttcaaagg cttcgcctgc ccccggtagc cagcgctgct
      421 ccacatcatg tagttctttt tcatatgcgt aattcatcag tctgcggaat gtttcgcttt
      481 gggtatacgc attttgaagt acggaggata gttcatcgta gcattcgtca taagtgtcgt
      541 catcaatttc tgtatcaggg tctattccac ccgcgcctga gataaggtac tccaccacac
      601 actctggctc cagacggaat tcactgttta tggcaaggct gtcatgagca aggcgtagcc
      661 gtgaggggtt tggtgcatgt tcgggaatat cggggaaaac aggtgtatct gcggtattta
      721 atccatatgt ggatactccg ctttgaggta ttaatctgta ggtgaccgga agcataattt
      781 cttattccct gactgcaatt atgaattatt taaattaaac aataatagtg tttttagtta
      841 atgtgccaca tacagataac gctatgattc aggcaaaacc aacaagtaat acgctgaaaa
      901 tgttatttat aatgaagctt aggggcgggg tttgtttaat aaaacaagga gggcttctgt
      961 ttgaatactt cttgtttata aaatcccttt atctcgacta aaatattgga tgggggaaaa
     1021 gcgttttatc attgtaatcc gggagtggag taggggtatg ttgactacct gtcagatcgg
     1081 ctcctgttaa tgctttcgct aaagttagag ctatcttatc taattttgca ccatttagtt
     1141 tggtgtcagt taagtctgag ccgaatagaa ttgcagcggt taagtttaca ccggacatgt
     1201 tagcgcaagt caggtctgcg tgagtcaggt ttgctttagt catgtttgaa cccattagat
     1261 ttacagcgtg tagatttgca caacacaaat ttgcaccgac taaatttaca ttagatagat
     1321 ttgtttcacg gaaatctgca ttagaagcat ctatgtctga caaatcttct ccctggaaat
     1381 ctttatgagc taggtttact ccgcgcaggt tcagaaaacc atcctcggtt ataagtgaat
     1441 cagg
//
LOCUS       DAJVKX010000278         1397 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.280, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000278 DAJVKX010000000
VERSION     DAJVKX010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1397
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.280"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..339)
                     /locus_tag="OPY25_004548"
     CDS             complement(<1..339)
                     /locus_tag="OPY25_004548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1353 domain-containing protein"
                     /protein_id="HCS0929967.1"
                     /translation="MSCFTSPAIMEMLGHYKWRVYEPFRFYLSEDKNDVIEVPVGFVT
                     DLATVPRIFWSLLPPDGEYAKAAIIHDYLYHYPLRNRKESDLIFLDGMKVLGVPKWKR
                     IIMYLAVRIFG"
     gene            complement(412..1221)
                     /gene="cdtB"
                     /locus_tag="OPY25_004549"
     CDS             complement(412..1221)
                     /gene="cdtB"
                     /locus_tag="OPY25_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytolethal distending toxin S-CDT"
                     /protein_id="HCS0929968.1"
                     /translation="MKKPVFFLLTMIICSYISFACANISDYKVMTWNLQGSSASTESK
                     WNVNVRQLLSGTAGVDILMVQEAGAVPTSAVPTGRHIQPFGVGIPIDEYTWNLGTTSR
                     QDIRYIYHSAIDVGARRVNLAIVSRQRADNVYVLRPTTVASRPVIGIGLGNDVFLTAH
                     ALASGGPDAAAIVRVTINFFRQPQMRHLSWFLAGDFNRSPDRLENDLMTEHLERVVAV
                     LAPTEPTQIGGGILDYGVIVDRAPYSQRVEALRNPQLASDHYPVAFLARSC"
BASE COUNT          416 a          308 c          279 g          394 t
ORIGIN      
        1 gccaaatatt cttacggcta aatacattat tatccttttc cattttggca cgcccagaac
       61 tttcatccca tccaggaata tgagatcgga ctcttttctg ttacgtaatg gataatgata
      121 caggtagtca tgaatgattg ccgctttggc atattcacca tccggtggca ataatgacca
      181 gaaaatacgc ggaacagtgg caaggtcggt aacgaatcct accggtactt caatgacatc
      241 atttttatct tcactgagat aaaacctgaa tggctcataa acacgccatt tataatgacc
      301 taacatttcc ataattgctg gactggtaaa acaactcata attttacctt ataataaata
      361 tatattctgc accttacgct caaagtacat gtcgtaaact ctatttactc attaacagct
      421 tcgtgccaaa aaggctacgg gataatgatc agaagcgagt tgtggattac gtaatgcttc
      481 aaccctttgt gaataaggtg ctcgatcgac aatgacccca taatctaaaa taccaccgcc
      541 aatttgcgtg ggttctgtag gtgcgagtac ggctacaact cgttccagat gctcagtcat
      601 caggtcattt tcaagtctgt ctgggctgcg attaaaatcc ccggcaagaa accaggataa
      661 atgccgcatc tgaggttgtc taaaaaaatt aatggtaacc ctgacaatag ctgcagcatc
      721 cggacctcca ctagccagtg cgtgcgctgt cagaaaaaca tcattaccca gtccgatgcc
      781 aatgacgggg cgagatgcga cagttgtcgg acgcaagaca taaacattat ccgctctttg
      841 tctggaaact attgccagat taacacggcg tgctccaaca tcaatagccg agtggtagat
      901 atatcttata tcctgacggc tggtggttcc gagattccag gtgtattcat caatgggaat
      961 acccactcca aaaggctgaa tatgtcgtcc ggtaggaacc gctgaggtgg gaacagcacc
     1021 ggcctcctgt accataagaa tatccacacc ggcagtacca cttaaaagct gtctgacatt
     1081 gacattccat ttactttctg tagatgctga agagccctga agattccagg tcataacttt
     1141 gtagtcactg atattagcgc aggcaaaaga aatatagctg cagatgatca tggtcagaag
     1201 gaaaaaaaca ggttttttca taatatctac tctcccgagc attacttctt tatctgaatg
     1261 atatatgtgt taataaccca ttgtttcatg acgttgattt tattctggca atgcctgact
     1321 tgtttctggt tctatgtctt gtgtaggtag taagatacat agtctaacgt caataaaact
     1381 aaaatggatg tctatta
//
LOCUS       DAJVKX010000279         1322 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.281, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000279 DAJVKX010000000
VERSION     DAJVKX010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1322
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.281"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(3..1256)
                     /locus_tag="OPY25_004550"
     CDS             complement(3..1256)
                     /locus_tag="OPY25_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCS0929969.1"
                     /translation="MSRTTILDDATASDIDEQRHSQPVQFIKRGTAPFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGVSPASSSVSLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASCCTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLLSGVMTDFFNWRIALAAIGCFALASALMFWKILPASQHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGAFVTLFNYIGYRLMLSPWELSQAV
                     VGLLSVAYLTGTWSSPKAGAMTSRYGRGPVMLFSTAVMLGGLLLTLFTSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRARRAKGQASSLYLFSYYLGSSIAGTLGGVFWHSYGWNG
                     VGGFIALMLVLAILVGTRLHHRLHA"
BASE COUNT          380 a          353 c          366 g          223 t
ORIGIN      
        1 tttcaggcgt gaagacgatg atgtagccgc gtcccgacca ggatggccag caccagcatt
       61 agcgcgataa aaccacctac gccgttccag ccgtaactat gccagaatac accgcctagc
      121 gtcccggcaa tactggaccc cagataatag ctgaaaagat aaagtgacga ggcctgtccc
      181 ttcgcccggc gcgcacgcgg gccaatccag ctactggcca cggagtgcgc ggcgaaaaag
      241 ccggcggaaa aaagcagcat cccggcaaaa atcagccaaa gcgaggtaaa aagcgtcagt
      301 aaaagcccgc ccagcattac tgcggtagag aacagcatca ccggcccccg gccatagcgt
      361 gaggtcattg cgccagcttt cggcgagctc catgtgccgg tgagataggc tacggataac
      421 agtccgacca cggcctggct taattcccag ggggagagca tcaggcgata accaatgtag
      481 ttaaacaggg tgacgaacgc gcccatcagt aaaaaacctt ccgcaaacag cagtggtaac
      541 cctcgatcgc gccagtggag acggaaatta ataaatagcg ttttaggccg tagcgacgtg
      601 ggacggaaat gttgcgaggc aggtaaaatc ttccagaaca tcagcgcgga cgccagcgca
      661 aagcatccga tggccgccag cgcgatgcgc cagttaaaaa agtcggtcat gacgccgctt
      721 aataaacgcc cgctcatccc gccgatggaa ttaccgctaa tatagagccc catagagaaa
      781 gcgacaaagc tgggatggat ttcttcgctc aggtaggtca ttcccaccgc ggcgacgccg
      841 cttaacgaca gaccgatcag cgcgcgcata atcagaatac catgccagct ggtcatcatg
      901 gttgataaca atgtgcagca ggaggctaat aacaaggcgg tgaccatcac cggtttacgg
      961 cctatcgcat cagaaagcgg gccggtaaaa agtaagccga tagccagcat ggcggtagaa
     1021 atagaaagtg aaacgctgct gctggcgggg gagacgccaa actcctggga aagtaccggt
     1081 agtataggct gaacgcaata aaggagtgcg aaagtcgcca ggcccgcgga aaaaagagcc
     1141 agcgtgacgc gcatgaaagg cgctgtaccg cgtttaataa attgaaccgg ctgagaatgg
     1201 cgttgttcat cgatatcgct cgccgtggcg tcatcgagaa tagttgtacg actcacgtta
     1261 aatccttgct ttacatctcc gtcaacagga gacgggtata accgacatgt aaagcataga
     1321 aa
//
LOCUS       DAJVKX010000280         1245 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.282, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000280 DAJVKX010000000
VERSION     DAJVKX010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.282"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(211..1005)
                     /gene="pduF"
                     /locus_tag="OPY25_004551"
     CDS             complement(211..1005)
                     /gene="pduF"
                     /locus_tag="OPY25_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol diffusion facilitator PduF"
                     /protein_id="HCS0929970.1"
                     /translation="MNDSLKAQCGAEFLGTGLFLFFGIGCLSALKVAGASLGLWEICI
                     IWGLGISLAVYLTAGISGGHLNPAVTIALWLFACFPKQKVLPYIIAQFAGAFGGDLLA
                     YVLYSSLFTEFETAHHMVRGSVESLQLASIFSTYPAAALNVWQAALVEVVITSILMGM
                     IMALTDDGNGIPKGPLAPLLIGILVAVIGASTGPLTGFAMNPARDFGPKLFTWLAGWG
                     NMAMSGGREIPYFIVPIVAPVIGACAGAAIYRYFIGKNLPCNRCKL"
BASE COUNT          377 a          322 c          258 g          288 t
ORIGIN      
        1 acccctcagt taatttattg ttataaacaa aacacattat ttacattcac tttttattag
       61 cattatcctg gccctgataa aaagtacaat gacaatatca aaagtctccc attgctggga
      121 gacgttttga tcagttcgtg aaagcagatc acgaaattat ctcacctgtt tttacgatac
      181 atcattgctg tgaatctggt tcgcattttc ttacagttta cagcggttac aaggtaaatt
      241 cttaccaata aaatagcgat atatggctgc tccagcacag gcgccgataa caggcgcgac
      301 aatcggcacg ataaaataag ggatctctcg cccaccgctc atcgccatgt tcccccaccc
      361 cgctaaccat gtgaacagtt tgggaccaaa atcacgcgcc gggttcattg caaaaccggt
      421 aaggggtcca gtagacgcgc cgataacggc aaccagtatc ccaataagca aaggcgcaag
      481 cggcccttta ggaataccat tgccatcatc cgtcaatgcc atgatcatgc ccatcaggat
      541 cgacgtaatg accacttcca ccaacgcagc ctgccataca tttagcgctg cggccggata
      601 ggtactgaaa atgctggcta attgcaaact ttcgacgcta ccgcgcacca tatgatgcgc
      661 agtctcaaat tcagtaaaaa ggctactata aagcacatac gccagcagat cgccgccaaa
      721 agcgccggca aactgggcaa taatataagg caatactttc tgtttgggga agcaggcaaa
      781 cagccacagc gcaatcgtca ccgcagggtt aagatgtccg ccggagattc cggcagtaag
      841 gtaaacggcc agtgaaattc caagccccca aataatgcaa atctcccata atccgaggct
      901 ggcgcctgcg actttgagcg cgctcaaaca accgatacca aaaaacaaaa agagtccggt
      961 gcctaaaaat tccgcaccac attgcgcctt tagagaatca ttcatgtgac accttctgag
     1021 caaagttcgt gtcctggcca gcgcaagttt cggctggcgg tagagtacag ctaacctcac
     1081 tataaaaagt gccgcctgta aattgttggc aacctgcgaa cctgtctccc ggaaaaatcg
     1141 tgttgcgata gcaaaatttt gcttttccga tatttttagc agcctatcat acgggagatt
     1201 cgagctataa aatacgcctg tgaaaataat aaaatattgc acaag
//
LOCUS       DAJVKX010000281         1207 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.283, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000281 DAJVKX010000000
VERSION     DAJVKX010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1207
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.283"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(1..471)
                     /locus_tag="OPY25_004552"
     CDS             complement(1..471)
                     /locus_tag="OPY25_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001662679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929971.1"
                     /translation="MKHFFLILFGISSPFICLATSVEFNVTKGIKASITWVDNKKVEY
                     EITGSDRVAKRGYYDVDTENNIHVKYGDYNFDGKEDFVIWYTDDGMGIYDIYRVFLYS
                     EKMADFKEIKPSCGDDFINLNLNKKKRELISLYYSHNEAQRCITNVFVGENKLK"
     gene            complement(590..1192)
                     /locus_tag="OPY25_004553"
     CDS             complement(590..1192)
                     /locus_tag="OPY25_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929972.1"
                     /translation="MYKKIVILVITLIIIFFGGGWYMHKSQQQMATLVISDSENALDY
                     PNKRKWFDASRWLSTSQYIKIDDFYLLNLKHHPVNNINDAGIIVILHFAIRDAIKKFP
                     ELSKLSQMDNKEFFHFMQNKLSNEYLRTKFNEDTLEPTDDYFLFFFTYNEISYEVELL
                     RKVTEHGMMFVPYGYQVNKKGDWHRMHPSTYSCFNDIQSN"
BASE COUNT          417 a          236 c          140 g          414 t
ORIGIN      
        1 tcactttaat ttattctcgc caacaaaaac attagtaata catctttgcg cctcattatg
       61 agaataatac agactaataa gctctctttt cttcttattc agatttaaat ttataaaatc
      121 atcgccacat gatggcttta tttctttaaa gtcagccatt ttctcagaat agagaaaaac
      181 cctatatata tcataaattc ccataccatc atctgtatac caaatcacaa aatcttcttt
      241 accatcaaaa ttataatcac catatttaac atggatatta ttttccgtat caacatcata
      301 atatcctctc tttgccacac gatcactacc tgtaatttca tactcaactt ttttattatc
      361 cacccaagtg attgatgctt ttattccctt tgtaacatta aattcaacag aagtagccaa
      421 acatataaat ggagaagaaa tcccaaaaag gattagaaaa aaatgcttca tatacttcaa
      481 ttaacccctc cgatatcaga caggattatt aactcctctt ctacatgctg caaaagcgac
      541 attaaacgac tcatcatcca tggtgttaaa aagctttcgt aacgtctcac taattacttt
      601 ggatatcgtt aaaacaagaa tatgtagatg gatgcattct gtgccaatcc ccttttttat
      661 taacttgata tccataaggc acaaacatca taccatgctc agtaactttc cgtaataatt
      721 ccacctcata agatatttca ttataagtaa aaaagaacaa aaaatagtca tcagtaggtt
      781 ccagtgtatc ttcattgaat ttggttctaa gatactcgtt agaaagttta ttctgcatga
      841 aatgaaaaaa ttccttatta tccatctggc ttaattttga taactctgga aatttcttta
      901 tcgcatcccg aattgcaaag tgtaatatta caataatccc tgcatcattt atattgttaa
      961 ctggatgatg cttaagattt aaaagataaa aatcatctat tttaatatat tgtgatgtgc
     1021 tgagccatct actggcatca aaccatttac gtttattcgg ataatcgagg gcattttcac
     1081 tatcagaaat aacaagggtt gccatttgtt gttgtgattt atgcatatac cacccaccgc
     1141 cgaaaaatat aataataagc gtaatcacta atattactat ctttttatac atctgatata
     1201 tcttatt
//
LOCUS       DAJVKX010000282         1194 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.284, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000282 DAJVKX010000000
VERSION     DAJVKX010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.284"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            91..921
                     /locus_tag="OPY25_004554"
     CDS             91..921
                     /locus_tag="OPY25_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929973.1"
                     /translation="MPDGLESTLEFDPSTSFINTTAVDNGITYSFTGEAVKATAHASC
                     TANQATNSAICVWDKSFSLPLTLLTKQNGITINQQNLTVSVIPGGGNNDTNQYSSLSG
                     HIIIDESVSSYTNYEPETSGIENLKLKWTVTVTEDTEGDVGIWNGSLVLNGSPASTLH
                     RYLLPEILDASFSENAIAHSTEVAMTGAKNNVELASVYLYHGNTPCDDTSLCNYSLNK
                     TSVSLVCHDLNAQLNFSNTCNASGTTHCLNGKVGTIKGTWERVNIDTTCAITVLIPYE
                     "
BASE COUNT          379 a          256 c          244 g          315 t
ORIGIN      
        1 cgataccatc cataccccat taccaacaaa cattcatatc ctttcatcgt gcactaagtc
       61 aggtggaggg ggggttgtat tccaggtaca ttgcctgatg gacttgaatc cactcttgag
      121 tttgatccat caacttcttt catcaataca accgctgtcg ataacggtat cacttatagt
      181 tttactggtg aagcggtaaa agcgacggca catgccagct gtacggctaa tcaggcaact
      241 aacagcgcaa tttgtgtatg ggataaatca ttttcacttc ccctcacctt acttaccaaa
      301 cagaacggaa taaccattaa ccagcaaaat cttacagttt cggtaatacc cggaggagga
      361 aataatgata ctaaccagta ctcatccctt tccggccata ttattattga tgaatcggta
      421 agcagctaca cgaattatga accggaaaca tcgggcattg agaatttaaa attaaaatgg
      481 actgtaacag tgacagaaga taccgaaggt gatgtcggta tatggaacgg atcacttgta
      541 cttaatggct ctccagcgtc caccctacat cgttatttgc ttccagaaat attagatgct
      601 tcattttctg aaaatgcgat agcgcacagt accgaagtcg ccatgactgg cgcaaaaaat
      661 aatgtcgagc tagcctctgt atatctctac catggcaata cgccatgcga tgatacatcc
      721 ttgtgtaact acagtcttaa taagacatca gtttctcttg tatgtcacga tctgaatgcg
      781 caacttaact ttagcaacac ttgtaatgct tcaggcacaa cacattgcct gaacggaaaa
      841 gtaggtacga taaagggtac ctgggagaga gtcaacatcg atacaacttg tgcaattacc
      901 gttttgatac cctacgaata aacacaggaa aaatgatgac cataagcaaa agaatcataa
      961 tttcatttat tctatttatg tgcttcacca acaatacatt tggatctgga tacgttaaga
     1021 tcaatgccga attgaatgat atggcaggca gaggggtagg cacagtgatt taaatagtaa
     1081 tctacggcga aggggaaatc tttctttttg gttgtacagg gaacgcttcg gcataccaga
     1141 aaggaggtca gcccctcacg ggatagatga aaaaacagat ccagaatcgc aggg
//
LOCUS       DAJVKX010000283         1073 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.285, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000283 DAJVKX010000000
VERSION     DAJVKX010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.285"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..179)
                     /locus_tag="OPY25_004555"
     CDS             complement(<1..179)
                     /locus_tag="OPY25_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HCS0929974.1"
                     /translation="MEHLKYRPDIDGLRAIAVLSVVIFHYFPSLLPGGFVGVDIFFVI
                     SGYLITSIILKSASN"
     gene            complement(196..450)
                     /locus_tag="OPY25_004556"
     CDS             complement(196..450)
                     /locus_tag="OPY25_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000703599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCS0929975.1"
                     /translation="MKISLVVLVFNEEDTIPIFYRTVHEFNELEKYKVEIIFINDGSK
                     DVTESIIKIIAVSDPLVIPFSFTRNFGNDARCTTILLIFF"
     gene            complement(419..808)
                     /locus_tag="OPY25_004557"
     CDS             complement(419..808)
                     /locus_tag="OPY25_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCS0929976.1"
                     /translation="MLKLFAKYTSIGVLNTLIHWGVFAFCMYGMHTHQALTNFSDFVI
                     AVSFSFYANARFTFNASTTAILYMMYMGFMGTLSAVVGWMADQCSLPPLVTLITFSAI
                     SLVCGFIYSRFIIFRDKNENLSCRPGF"
BASE COUNT          359 a          188 c          211 g          315 t
ORIGIN      
        1 ttgtttgatg cagattttaa tattattgat gttataaggt atccagatat cacaaagaat
       61 atatctactc caacaaaccc acccggcaat aatgatggga aataatggaa tattaccaca
      121 gataaaaccg ctattgcgcg taatccatct atatcaggtc tgtattttaa gtgttccaac
      181 ttaaattacc tcaatttaaa aaaagattaa taaaatggtt gtgcatcttg catcattccc
      241 gaagtttcgt gtaaacgaaa acggaatgac gagtggatca gatacggcta ttattttaat
      301 tattgactcc gtcacatctt tacttccgtc attaataaaa ataatctcaa ctttatattt
      361 ttcaagttca ttaaactcat gtaccgttct atagaaaatc ggtatcgtgt cttcttcgtt
      421 aaaaaccagg acgacaagag agattttcat ttttatccct gaagataatg aatctggaat
      481 agataaagcc gcataccagg ctaattgccg agaaagtgat gagggtaacc aatggtggca
      541 aagaacattg gtcagccatc catccaacaa cagcgctcag tgttcccatg aatcccatat
      601 acatcatgta gagaattgca gtagtgctgg cattaaaggt gaagcgcgca ttagcataga
      661 agctgaacga tacagcgata acaaaatcgg aaaagttcgt cagcgcctga tgcgtatgca
      721 tcccatacat acagaaagca aatactcccc aatgaatgag cgtgttaaga acaccgatcg
      781 atgtgtactt agcgaataac ttcaacatta tgaaaattag ccgattcaga aaggtctgga
      841 gtgtagcact acaaattggt ttgatcgata taagcgatca ataattgtat ttttaatagt
      901 tttaagctat tgagttttaa tatattgatc gatgttatcg atcaattggt attgctgatt
      961 gccaagcgtc ttggaataaa aacgggacat gtaaagcttt acatcgtctt acaaggcttt
     1021 gcatgttttt tcagagagag gtacttgaaa gggtggaagt gctggggaga ggg
//
LOCUS       DAJVKX010000284         1053 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.286, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000284 DAJVKX010000000
VERSION     DAJVKX010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.286"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..836)
                     /gene="sifB"
                     /locus_tag="OPY25_004558"
     CDS             complement(<1..836)
                     /gene="sifB"
                     /locus_tag="OPY25_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector SifB"
                     /protein_id="HCS0929977.1"
                     /translation="MPITIGRGFLKSEMFSQSAISQRSFFTSLWEKIKDFFCDTQRST
                     ADQYIKELCDVASPPDAQRLFDLFCALYELSSPSCRGNFHFQHYKDAECQYTNLCIKD
                     GEDIPLCIMIRQDHYYYEIMNRTVLCVDTQSAHLKRYSDINIKASTYVCEPLCCLFPE
                     RLQLSLSGGITFSVDLKNIEETLIAMAEKGNLCDWKEQERKAAISSRINLGIAQAGVT
                     AIDDAIKNKIAAKVIENTNLKNAAFEPNYAQSSVTQIIYSCLFKNEILMNMLEESSSH
                     GLL"
BASE COUNT          315 a          209 c          197 g          332 t
ORIGIN      
        1 agcaggccat gagaggaact ttcttccagc atattcatta gtatctcatt cttaaacaaa
       61 catgaataaa taatttgagt aactgagctt tgtgcataat ttggttcaaa cgctgcattc
      121 tttaagttag tattctcaat aacctttgcg gctattttgt ttttgatagc atcgtcaata
      181 gctgttacac ctgcttgtgc gatgcccaga ttaatcctgg aggagatggc ggcttttctt
      241 tcctgttcct tccagtcaca taaattcccc ttttctgcca tggcgataag cgtctcttct
      301 atatttttta ggtcaacgga aaatgttata ccgccggata gcgagagttg taaccgctca
      361 gggaacaagc aacatagcgg ttcacaaaca taagtgctag cttttatatt aatatcagaa
      421 tatcttttca ggtgggcaga ctgagtatca acacagagca ctgttctatt cattatctca
      481 taatagtagt gatcctgacg tatcataata cataacggaa tatcttcgcc atctttaata
      541 cagagatttg tatactgaca ctcagcatct ttatagtgct gaaaatggaa atttcctctg
      601 catgatggtg atgataattc atataacgcg caaaataaat caaataaacg ttgcgcgtca
      661 ggcggagagg caacatcaca taattccttt atatattgat cggcagtgga tctttgcgtg
      721 tcacaaaaaa aatctttaat cttttcccat agtgacgtaa agaaggagcg ttgagagata
      781 gcactttgag aaaacatctc actctttaaa aatcctctcc cgatagtaat tggcataatg
      841 tagaccacaa gtgattatat gatacttcat tactggaata ggtggtattc gaaatattat
      901 cccatgttgc ccatcggttt gcctatcggt gaaacacctg atttttgctt tgtcctgaac
      961 cgtcaacatt attgttaaaa tcgacccgtg gctttagtca gtccacgcct cctggccatg
     1021 aagtatgtca ggtaaaacga atgaaagtaa aat
//
LOCUS       DAJVKX010000285         1051 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.287, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000285 DAJVKX010000000
VERSION     DAJVKX010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1051
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.287"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..575
                     /locus_tag="OPY25_004559"
                     /pseudo
     CDS             1..575
                     /locus_tag="OPY25_004559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459704.1"
                     /note="catalyzes the formation of UDP-galactofuranose from
                     UDP-galactopyranose; frameshifted; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            572..>1051
                     /locus_tag="OPY25_004560"
     CDS             572..>1051
                     /locus_tag="OPY25_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCS0929978.1"
                     /translation="MMKCTALIVTFNRLEKLKKSVRETVKAGFSSIVIVNNGSSDGTR
                     EWLSSLSEPGITILNLKDNLGGAGGFKVGSQYICSYSNADWVFFYDDDAYPEINILKH
                     FSLLDTSSYRIFASRVQDTYGRSCRMNLPFIRVPSTVFETIYYAMRPERFSPVRTQVT
                     "
BASE COUNT          312 a          184 c          221 g          334 t
ORIGIN      
        1 ataccaaaat ttggttatac acaaatggtc aagtccattg tcgaacacga aaatatcgct
       61 gttgaactat gtcgctcctt cactcaagaa atgcggacaa attatgatca tgtttttttc
      121 agtggcgcgc tggatgcctt ttactcctgt caatatggcc gactggaata tcgtacatta
      181 gactttaaaa aaataatttg ccagagtgat tatcaaggat gcgcagtaat gaattattgt
      241 tcaatagata ctccttatac tcggattact gagcacaaat atttttctcc gtgggagaga
      301 catgaagctt caatatgtta tcaagaatat agtcgggaat gtgaagctgg tgatataccc
      361 tactatcctg ttcgcagggc agataaaatg gatttactga ataaatatct gtcgcgggct
      421 aaaaaagaaa aaatattact ttcattggtc gtcttggcac ttatcgttat ctcgatatgg
      481 acatcacgat agctgaagca ttacagacgg cggacgtata cttaacgtcg ctatatgaac
      541 aaaaagaaat gccagctttt acagttaccg tttgatgaag tgtacagcgc taatcgtaac
      601 ttttaatcgt cttgaaaaat taaaaaaaag tgtgcgagag actgttaagg cgggtttttc
      661 ctctattgtt atcgttaata atggctcaag cgacggtacc agggaatggc tttcttcatt
      721 aagtgaacct ggcatcacga tacttaatct taaagataat cttggtggtg ctggcggatt
      781 taaagtaggt agtcaatata tatgctcata tagtaatgcc gattgggtat ttttttatga
      841 tgatgatgct tacccggaaa ttaatatttt aaagcatttc tcgttattag atacatcaag
      901 ttaccgtata tttgcgtcgc gagttcagga cacctatggg cggtcttgtc ggatgaattt
      961 gcctttcatt agggtcccat ctacggtgtt tgagactatt tattatgcga tgcgcccaga
     1021 gaggttttct ccagtaagaa ctcaggttac t
//
LOCUS       DAJVKX010000286         1051 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.288, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000286 DAJVKX010000000
VERSION     DAJVKX010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1051
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.288"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            17..970
                     /gene="sopD"
                     /locus_tag="OPY25_004561"
     CDS             17..970
                     /gene="sopD"
                     /locus_tag="OPY25_004561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector SopD"
                     /protein_id="HCS0929979.1"
                     /translation="MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHF
                     RAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIK
                     MDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTW
                     HPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACI
                     NAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQ
                     DYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT"
BASE COUNT          338 a          204 c          231 g          278 t
ORIGIN      
        1 tttgaaggaa aatattatgc cagtcacttt aagcttcggt aatcatcaaa attatacgct
       61 taatgaaagt cggcttgctc atctgttaag cgcagataaa gaaaaagcaa tccatatggg
      121 gggctgggat aaagtccagg atcattttag agcggaaaaa aaggaccatg cgctggaagt
      181 gttacactcc atcattcacg ggcagggccg tggtgaacct ggagagatgg aagttaacgt
      241 agaggatatc aataaaattt acgcctttaa acggctacaa catctggcct gcccggctca
      301 tcaggatctg tttactatca agatggacgc ttctcagaca caatttttac ttatggtcgg
      361 cgacacggtg atcagccaaa gcaatattaa ggacatcctc aatatatcag atgatgcagt
      421 gatagaatct atgagtagag aagagagaca gttattttta caaatatgcg aggtgattgg
      481 tgcgaagatg acctggcacc cggaattact tcaggagtcg atttctactc tacgaaaaga
      541 agtgacgggc aatgcacaaa tcaaagcggc ggtttatgag atgatgcgtc ccgcagaggc
      601 tccagaccac ccgcttgtcg aatggcagga ctcgcttact gaagatgaaa aatcgatgct
      661 ggcctgtatt aatgccggta actttgagcc tacaactcag ttttgcaaaa taggttatca
      721 ggaggtacaa ggtgaagtcg cttttagcat gatgcatccg tgcatctcct atttactaca
      781 tacctattca ccgtttgcag agtttaaacc aacaaattcc ggttttttaa aaaaacttaa
      841 tcaggattat aacgactacc atgcaaaaaa aatgtttatt gatgtaattc ttgaaaagct
      901 atatctaacg catgaacgtt ctttgcacat tggtaaagat gggtgcagtc gtaatatatt
      961 actgacataa agatagccag taatataacc aatttaaaat ccggctgcct gccggatttt
     1021 acatagcagc aagtataatc ataccgcgta a
//
LOCUS       DAJVKX010000287         1004 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.289, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000287 DAJVKX010000000
VERSION     DAJVKX010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1004
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.289"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..216
                     /locus_tag="OPY25_004562"
     CDS             <1..216
                     /locus_tag="OPY25_004562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase"
                     /protein_id="HCS0929980.1"
                     /translation="ATKPWHAWANYPSVIYYKNARLNSPWKDSPAKDARTIVEFKKRY
                     KHLLVQGHYFKGLLAGSAYLYRKLFHK"
     gene            239..937
                     /gene="rfaY"
                     /locus_tag="OPY25_004563"
     CDS             239..937
                     /gene="rfaY"
                     /locus_tag="OPY25_004563"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HCS0929981.1"
                     /translation="MIIEKKVKNYTVFVKKDGEKYIEIFKDFLSYNHQVIKVFRNIED
                     TKVVLINTDYGKYILKVFSPKVKSTERFFKSLVKGDYYEKLFHQTDRVRREGFAALND
                     FYLLAEIKTLRYVKTYVMIIEYIEGIELVDMPEISDEVRGKIKQSIYSLHQHGMVSGD
                     PHKGNFILQGNEIRIIDLSGKRPSRQRKAKDRIDLERHYGIKNNVRDIGFYLLIYKKK
                     LRNFLRRIKGKEKR"
BASE COUNT          341 a          160 c          198 g          305 t
ORIGIN      
        1 gctacaaaac catggcatgc ctgggcaaat tatccttcag ttatctatta taaaaatgca
       61 cgactgaact cgccctggaa agattctcct gcaaaagatg cgcgtaccat agttgaattt
      121 aagaagcgat ataaacatct tctcgtgcag gggcattatt ttaaaggcct tctggctgga
      181 agcgcatatc tttatcgtaa acttttccac aaataattcc cttccctaaa tctccattat
      241 gattattgaa aaaaaggtta aaaactatac cgtctttgtc aaaaaagacg gtgaaaaata
      301 tattgagata ttcaaagatt ttctatctta taatcatcag gttattaaag tcttccgtaa
      361 tatagaagat acaaaagttg tattgattaa tacagactac ggaaaatata ttctcaaagt
      421 atttagtcca aaagtaaaaa gtactgaacg ctttttcaaa tcgttagtaa aaggagatta
      481 ctacgaaaag ctttttcatc agacagatcg cgtgcggcgt gaagggtttg cggcgcttaa
      541 tgatttttac ctgctggcgg agattaaaac attacgctat gtaaaaacat acgtgatgat
      601 aattgagtat attgaaggta ttgaacttgt tgatatgcca gaaatttctg acgaggtgag
      661 agggaaaatc aaacagtcga tatattctct gcatcagcat ggtatggttt cgggcgatcc
      721 ccataaaggt aactttatcc tgcaaggtaa tgagatcaga attatcgatt tgtccggaaa
      781 aagaccttcc aggcaacgaa aagcaaagga tcgtattgat ttagaaagac attatggtat
      841 caaaaataat gtgagagata ttggatttta cttattgatt tataagaaaa aacttcgaaa
      901 tttcttgcgt cgtattaagg gtaaggaaaa gcgctgatca atgtagcacg tttggtttaa
      961 tttaaggggc tgactgactt ttatttgctg cagcgttatg acat
//
LOCUS       DAJVKX010000288          984 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.290, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000288 DAJVKX010000000
VERSION     DAJVKX010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..984
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.290"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..751)
                     /locus_tag="OPY25_004564"
     CDS             complement(<1..751)
                     /locus_tag="OPY25_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929982.1"
                     /translation="MKNKKYINSLLAACVLFSCFNGQAAELKRVYGKLSFGYGDWNKG
                     FVNVDRGEVWKAVADFGAVFDRGEFASFYEMNVLNHPVEGRNHVTQFLGHYRVVEGSN
                     FTAMMKLYMSMENKFGDELNMMYGVGYLGLTSPSGFIKPYFAVHNLSNDYTSKKYGQA
                     TGFNGYVLGWVAAYNFDMFNEKFVISNWNEVEMDRNDAYAEQQGGTTGLNGAVTFTWK
                     FMPRWTASVSYRYFNNKLGYNGYGDRMNYLIG"
BASE COUNT          289 a          217 c          194 g          284 t
ORIGIN      
        1 agccgatcag gtaattcata cggtcgccgt agccgttata ccccaattta ttattgaagt
       61 aacggtaaga gacggaggcg gtccatcgcg gcataaattt ccatgtaaac gttaccgcgc
      121 cgttcaggcc ggtcgtccca ccctgttgtt cggcgtaggc atcattacga tccatttcaa
      181 cttcgttcca gtttgaaatg acgaactttt cattaaacat atcgaagtta taagccgcga
      241 cccaaccgag aacataaccg ttaaagcctg tcgcctgtcc atacttttta gaggtataat
      301 cgttcgataa gttatgaaca gcgaaatagg gcttaataaa gcctgatggg ctggttaaac
      361 ccagataacc taccccgtac atcatgttta attcatcacc gaatttattc tccatcgaca
      421 tatagagttt catcattgcg gtaaagttag agccttctac taccctataa tgtcccagaa
      481 attgggtaac atggttacgg ccttctaccg gatggttgag cacgttcatt tcataaaatg
      541 atgcaaattc gcccctgtca aacacggcgc cgaaatcggc taccgctttc cacacttcgc
      601 cgcgatcgac attgacaaag cctttattcc agtcgccata tccgaagcta agtttaccgt
      661 atacgcgttt caattccgct gcctggccat taaagcaaga gaaaagaaca catgcggcga
      721 gtagactatt aatatatttc ttatttttca tgctcaactc catgaggtaa aaacacagtg
      781 aaatgttgtg taaagaagcg aattctaagg agtgtctttt tatacgtagg tgatagatgt
      841 ctcaaaaata tcagcgacat ataatcgtca aatattcgtg tcagataatg ttgtttatta
      901 cgtgataact atttgattta tagtttatgt ctctgttgta aaagtcacac cggatagcat
      961 gaaattaatg aaacttcgaa tggg
//
LOCUS       DAJVKX010000289          978 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.291, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000289 DAJVKX010000000
VERSION     DAJVKX010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.291"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            318..965
                     /gene="narP"
                     /locus_tag="OPY25_004565"
     CDS             318..965
                     /gene="narP"
                     /locus_tag="OPY25_004565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HCS0929983.1"
                     /translation="MPEVTPFQVLIVDDHPLMRRGIRQLLELDPAFYVVAEAGDGASA
                     IDLANRIEPDLILLDLNMKGLSGLDTLNALRRDGVTAQIIILTVSDSASDIYALIDAG
                     ADGYLLKDSDPEVLLEAIRKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ"
BASE COUNT          245 a          233 c          248 g          252 t
ORIGIN      
        1 taaggaattt cctgccagta aagatagtct ggacttacgg acgcaagggc gcagctacat
       61 atgccacact tctgttatgt cacattgtcc gaaaaaagcg tccagaccag tattcaactt
      121 cagggagtat tctgttttct ctcacaacag gttgttttat cctttctatc gttcagctaa
      181 tgactcgcct gtcacaggtt ttactactta cccatgcact aattaaggta aaatttacgc
      241 gcttgacaat gtggcaaatc tggacgattt ccgcgctgaa aacaataatc attctaataa
      301 aactcaggag atatagcatg cctgaagtaa caccttttca ggtgcttatt gtggacgacc
      361 atccacttat gcggcgaggt attcgtcaat tactggaact ggacccggct ttttatgtcg
      421 ttgccgaagc gggtgacggg gcgagtgcga tcgatctggc gaatcgcatt gagcccgatc
      481 tgatcctgct ggatctgaat atgaaaggtc tgagcgggtt agataccctg aacgcgctac
      541 gccgggatgg tgtgacggcg caaattatta ttcttaccgt ctcggattcc gccagcgaca
      601 tctacgcgct gatcgacgcc ggcgccgacg gttatctgct caaagatagc gatccggaag
      661 tgctgctgga ggccattcgc aaaggcgcta acggcggtaa agtctttagc gatcgggtca
      721 atgaatatct gcgtgagcgt gaacggtttg gcgcgcagga agatcccttt agtatcctga
      781 ccgaacgaga gttagatgtc ttgcatgagc tggcgcaggg gctttctaac aaacagattg
      841 cgtcagtact gaatatttct gagcagacgg ttaaggtgca cattcgtaat ctacttcgca
      901 agctaaacgt gcgctcgcgc gtcgcggcga ccattctatt tttacaaaca cgcggaatgc
      961 agtaacaagc caggcccg
//
LOCUS       DAJVKX010000290          971 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.292, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000290 DAJVKX010000000
VERSION     DAJVKX010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..971
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.292"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(180..398)
                     /locus_tag="OPY25_004566"
     CDS             complement(180..398)
                     /locus_tag="OPY25_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929984.1"
                     /translation="MKSHDRLRIVFAQARQNWRAFAYVMQVHENHYTKRAGVAGIRAR
                     AQRLTLGPKSLQAKKLTFIFQLELSAKK"
     gene            complement(494..727)
                     /locus_tag="OPY25_004567"
     CDS             complement(494..727)
                     /locus_tag="OPY25_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI family protein"
                     /protein_id="HCS0929985.1"
                     /translation="MRIEIMIDKEQKISQATLDALESELYRNLRPLYPKTAIRIRKGS
                     ANGVELSGLKLDEDKKRVMEIMQQVWEDDSWLH"
     gene            complement(739..927)
                     /locus_tag="OPY25_004568"
     CDS             complement(739..927)
                     /locus_tag="OPY25_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929986.1"
                     /translation="MQDYILESLKLQRIDFFIKLVAASECSDEEKRLAIQWVSELTDE
                     LMAKIRSHEYCRSMDVTS"
BASE COUNT          223 a          269 c          202 g          277 t
ORIGIN      
        1 acatctacag gatgcgtgtg cttctgcttc ttaccttcag gcttatgttt agcctcatca
       61 tcacaaagga aatctcggtc gcaggggcca tgctgctgcc acttaaatcg actcagtaga
      121 tcctccgata tgcgtttcgc caaatcttca atagggccgt tctctgccat ttgatttcct
      181 tacttttttg cagacaattc taattgaaag ataaaggtaa gcttttttgc ttgcaaggac
      241 tttggaccta acgtgagacg ctgagcgcgc gctcgtatcc ccgccacgcc tgcccgcttt
      301 gtgtagtggt tttcatgcac ctgcatgaca taagcaaaag cccgccagtt ctggcgggcc
      361 tgagcaaaaa cgatcctcaa acgatcatgc gatttcatgc ggcatagaca tgcacaacag
      421 cgctaacgcc tcacgtggct cgttgttcaa ccttgcggac ggtaaaaacc agttttatcg
      481 tccgcaacgt tcgctaatgt aaccagctgt cgtcctccca gacctgctgc attatttcca
      541 tcactcgctt tttgtcttca tccagtttta acccgctcag ttcaacacca ttggcgctgc
      601 ccttgcggat acgaattgct gttttgggat acagagggcg caaattacgg taaagctcgg
      661 attcaagggc gtccagtgta gcctggctaa tcttctgctc tttatcgatc attatttcaa
      721 tgcgcataca gatttccctt aactggttac gtccattgac cggcagtatt catggctgcg
      781 gattttcgcc atcagctcgt cggtcagttc tgacacccac tggatagcca gccgcttttc
      841 ttcgtcgctg cactcactag ccgctacaag cttaataaaa aaatcaatgc gctggagctt
      901 caacgactcc aaaatatagt cctgcatctt ccctcctatc acgacctcgg atacgcatta
      961 actgtatgta t
//
LOCUS       DAJVKX010000291          964 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.293, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000291 DAJVKX010000000
VERSION     DAJVKX010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..964
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.293"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            120..824
                     /locus_tag="OPY25_004569"
     CDS             120..824
                     /locus_tag="OPY25_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCS0929987.1"
                     /translation="MKKMMNDAFAKDNNENLLHSFLFSQQAKPHAAIDALFSALLPFG
                     QPFTLGIGDEFYLQANDEHYIVLLESGIVSFCRDDNRLHISSSFAPSVVGMVDSYGAT
                     YNVPARPEHFLLAETVCSGRFVRLPDFIKIADECDLWHDVARCLAYRLMVMSARDREL
                     VGVDSYLKVRALLIEIWAYPQAYRENIIVLNFIQRRTGISRSRTMKILSELKKGGYIH
                     IDNGRLTALGKLPVAY"
BASE COUNT          254 a          183 c          226 g          301 t
ORIGIN      
        1 aatattgcgt attagtgcgt tgtgaataca gaaatactgc atagcgatgt tatttattat
       61 taatttaagt actttttgag aggttatact gtggcgctac attgagtaga caaccgttaa
      121 tgaaaaaaat gatgaacgac gcttttgcta aagataataa tgagaattta ttacactctt
      181 ttcttttttc tcagcaggct aaacctcacg cggcgattga tgccttattt tcggccttgt
      241 tgccatttgg tcaaccgttt acgctgggta tcggcgatga gttttattta caggccaatg
      301 atgaacacta cattgtatta ctggagtcag gaattgtttc tttctgtcgt gatgacaacc
      361 gactccatat atcttcatcg tttgcgccat cggtcgtggg tatggttgac agctatggcg
      421 ctacctataa cgttcccgcg cgcccggaac actttttgct cgcagaaacg gtttgtagcg
      481 gtagatttgt tcgcctgccg gattttataa aaatcgccga tgaatgcgat ttgtggcacg
      541 acgtggcccg ttgtctggct taccgtctga tggtgatgag cgcgcgcgat cgtgaattag
      601 tcggcgtcga ttcttacctg aaagttcggg cgctgctgat tgaaatctgg gcttatccac
      661 aggcctaccg ggaaaacatt atcgtattga attttattca acggcgtacc gggatatcgc
      721 gcagtcggac tatgaagatt ctgtctgaac taaaaaaagg cgggtatatc catattgata
      781 atgggcggct gacggcactc ggaaaactgc cagtggcgta ttaatgcact atacgcaacg
      841 atatatttac atatctcaac tgaatttgcc tgttatcgtt aataaaatgt tttattgaaa
      901 attgttaaga agattatttt taaaaagtca atatgactaa aggagatagg ccgaacggct
      961 ggtg
//
LOCUS       DAJVKX010000292          945 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.294, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000292 DAJVKX010000000
VERSION     DAJVKX010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.294"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            392..>945
                     /locus_tag="OPY25_004570"
     CDS             392..>945
                     /locus_tag="OPY25_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3626 domain-containing protein"
                     /protein_id="HCS0929988.1"
                     /translation="MLKPIFYSGSVKVPECLETDKEKNVGRTPLSSDIQQIKNVVEDI
                     PPFPESRAVGGSVSAAYRLSFDEVFCGLSNEERKKVYGRLFGKQVLAHIHSRCQRDAD
                     IIREKALRRISRECGTEIDCALLLNKMVDILQNARLTINFNAAKIDFVSLLKNKEYLN
                     SYALGCRPGDLPAYNVGRDSVETKA"
BASE COUNT          289 a          160 c          208 g          288 t
ORIGIN      
        1 gtattcgaac ggttatcaaa ataatttatc aaaacgtcct caattcagac cgcaatagta
       61 gtccatcctt taccccgatc gtcatgataa cctgagaccc cctgaaagct gatagttacc
      121 gattttgatt gtggtggttt tctttatgat gtgtggtttg gctatttttt gaaagtgcct
      181 taccagattt attgttatta tcaggggatt atttcaataa aaggtgatga tttattgcct
      241 gcaatagtgg gtagattaag cattttatga aattattagt gtctttattt gcacttctac
      301 aagactgtta agaggtgttg aaatatcagc ctggtaaaga atacgtcagc gaaagtgaat
      361 gctatattag tcataaaaat tcaggagaca tatgctcaaa cctatcttct acagtggaag
      421 tgtgaaggtt ccggaatgtc tggaaacaga taaggaaaaa aatgtcggac gtactcctct
      481 gtcttcagac attcagcaaa ttaaaaatgt tgttgaagat attccgccat ttccagaaag
      541 cagagcggtg ggaggttctg taagcgcagc gtacaggctt tcttttgacg aagtgttttg
      601 cggtctcagc aatgaagagc gtaaaaaggt gtatggtcgc ctttttggaa aacaagtact
      661 tgcgcatatt cattccaggt gtcagcgcga cgctgacata ataagagaaa aagcgctcag
      721 gcggataagc cgtgagtgtg gtaccgaaat agattgcgct ctcttactaa ataagatggt
      781 ggatatttta caaaatgccc ggctgacaat aaattttaat gcagcaaaaa ttgactttgt
      841 ctctctctta aaaaataaag aatatctgaa ctcttatgca ttaggttgca gaccaggaga
      901 tttacctgct tataatgtcg ggcgtgattc agttgaaact aaagc
//
LOCUS       DAJVKX010000293          895 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.296, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000293 DAJVKX010000000
VERSION     DAJVKX010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..895
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.296"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..191)
                     /locus_tag="OPY25_004571"
     CDS             complement(<1..191)
                     /locus_tag="OPY25_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001680219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ESPR domain-containing protein"
                     /protein_id="HCS0929989.1"
                     /translation="MNRIFKVLWNAATGTFIVTSETAKSRGKKSGRRKLAVSALVGLS
                     SIMVSADALANAGNDTGSI"
     gene            complement(235..891)
                     /locus_tag="OPY25_004572"
     CDS             complement(235..891)
                     /locus_tag="OPY25_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HCS0929990.1"
                     /translation="MLALGFTFFLSGCDYFADKHLVEELKKQQKEQEAKINLLEKQQK
                     EQEVKINLPEKQQTTVINTTQKIAEVVGRVERKQRLFDYTELDPSQTHYFIINNGNIG
                     LAGRILSIEPIDNGSVIHLDLVNLLSIPVSNLAFNMTWGTKKPSEAKDLPRWRQLLLN
                     TKMDSTIELLPGAWTNVTLTLKGVSPNNLKYLKIGIDMENVIFDSIQPINDTKKKPKK
                     "
BASE COUNT          208 a          177 c          191 g          319 t
ORIGIN      
        1 ttaatgctgc cggtatcgtt ccctgcattg gccagcgcat ctgcagagac cataatactg
       61 ctaagaccga cgagtgcgga aaccgccagc tttctgcggc cgcttttttt tccgcggctt
      121 tttgccgtct cgctggtgac aataaatgtt cccgtagcgg cattccagag gactttaaat
      181 attctgttca tgaataagtg ctttcctttt ctaaaatagt tgtatcaatg gctattattt
      241 ttttggcttc tttttcgtat cattaatagg ttgtatgctg tcgaatatga cattctccat
      301 gtcaatacct atttttagat acttaagatt attgggcgat acgcctttta atgttagcgt
      361 gacgtttgtc catgctcccg gtaagagttc gattgtcgag tccattttcg tgttgagcag
      421 gagttgtcgc cagcgaggca gatcttttgc ctcggaaggt tttttcgtac cccatgtcat
      481 attaaacgca aggtttgata cgggaatgct gagtaagtta actaaatcaa gatgaataac
      541 acttccatta tctattggct caatagatag aatacgcccg gctaatccga tattgccgtt
      601 gttaataata aaatagtgcg tttgtgatgg gtccagttct gtatagtcga atagccgttg
      661 tttgcgttca acgcggccaa cgacttcggc gatcttttga gtcgtgttga taaccgtagt
      721 ttgttgtttt tctggcaaat ttatctttac ttcttgttct ttttgttgtt tttctaacag
      781 gtttatcttt gcttcttgtt ctttttgttg ttttttcagt tcttcaacaa ggtgcttatc
      841 tgcgaagtaa tcacaaccag acaaaaaaaa tgtgaatccc aaagcaagca ggggg
//
LOCUS       DAJVKX010000294          865 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.297, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000294 DAJVKX010000000
VERSION     DAJVKX010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.297"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            495..680
                     /locus_tag="OPY25_004573"
     CDS             495..680
                     /locus_tag="OPY25_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001729072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3289 family protein"
                     /protein_id="HCS0929991.1"
                     /translation="MQDHFSLDSNDITHWLYSHWDVFKIWFVLQHYEKEGYEFKPFIH
                     KIILDALRRQGKKSPGA"
BASE COUNT          291 a          134 c          183 g          257 t
ORIGIN      
        1 taataaatat tagagtatca ttgagtaatt ttagtgacga tcaaatactt catggttttg
       61 atggcatgtt aataataaat aaaaaaaatg aagagatcga gatttttact attccagtag
      121 ttggtgctaa ttactcatat aaagataaat ttttagtaaa cgtccatgat tttgaattat
      181 ttgatggaaa gatctgtaac gctttgatgc ctatagatag ttatttttca ccataagaag
      241 ggttgttgaa taaatcaaat taccctgtac cgtcaaatgt acctaccgtc gacacgggta
      301 acggatctac atcttctggg aagcaaaagg caacaacaaa agatgcggaa caattgccga
      361 cagagggaaa taaaatcgtg gagggcctat agctacgggc tgagattatc tgttcatgat
      421 atgtatggca cacacgttac cataacatca ttgaatgtat caaaaatgcc tacgcagcaa
      481 acgggcatta caggatgcag gatcatttta gtcttgacag taatgatata acacattggc
      541 tttatagcca ttgggatgtc tttaaaattt ggtttgtact tcaacattat gagaaagagg
      601 ggtatgagtt taagccattt atacacaaaa tcattctaga tgcattgcgg cggcaaggga
      661 agaaatcccc gggagcatag ataactctgt gaccggggtt tctgagcgca gccaacaaag
      721 aggcagctta aaggatgaag tgtatattac agaaataaat accaccgtaa aaatctcagg
      781 tgtcagagga tattactcct gatttggtat gtattgtcgg caaggtattt gtttgtattg
      841 ttaacatagc atagtccgat atttt
//
LOCUS       DAJVKX010000295          839 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.298, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000295 DAJVKX010000000
VERSION     DAJVKX010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..839
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.298"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
BASE COUNT          229 a          210 c          171 g          229 t
ORIGIN      
        1 gttttaattc ggacgtattt cgggccattt tgcgtataaa tctcccgacc aaacaaactc
       61 actgcccaat acatcactcc cctcttccat tgggggactc ccgatgccaa atacccatgt
      121 agacgaaggc ttaatagtga tgccaacaaa agcgatcgcg aaaagttgaa caggtggcta
      181 gtttcagatt aaacacattg gttagtcatc ctgaacaagt aaaatccgcc gcaactggca
      241 gccattcaat actcgcacta tcgaacgatc gccagcttgc cgcagcccgt tcttgcatac
      301 gatgtggctg cggttccatc acatcaggaa tgtgaaaatc tggataaacc tgccacttaa
      361 cctgaagcag gtcttcatag cgggtggtat accgaggcga aagcatttct cttaaggtcg
      421 ccatataaaa acattctatt acaacgagtt atctcctcct gcctccgccc cggcgcaaag
      481 ctatagtttt tctatctcct tgtgaaacaa acaattattc ttgctatagc gctgattaac
      541 aatcgttcgc gggcaacgta cattcagcga gtttcagagc ttcctgacgg aattccgccg
      601 gtgctgtttc cgggacttct tactggttga tacagatcct gcctcttact tgagaattta
      661 ctcatttagc cgtatgtcca ttatgggtgg ataagatcat ttatcatcgt aagggttgaa
      721 agcgataagt taaacttgtc ctggctcaac aagggaaccc gactaatgat gagctcttca
      781 tcttcaaggc gttttatgcc ttccagcaag aatagatatt aaatcgacaa ctgctgcca
//
LOCUS       DAJVKX010000296          828 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.299, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000296 DAJVKX010000000
VERSION     DAJVKX010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.299"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>828
                     /locus_tag="OPY25_004574"
     rRNA            <1..>828
                     /locus_tag="OPY25_004574"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          205 a          188 c          265 g          170 t
ORIGIN      
        1 ggttgtaaag tactttcagc ggggaggaag gtgttgtggt taataaccgc agcaattgac
       61 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt
      121 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtctgt caagtcggat
      181 gtgaaatccc cgggctcaac ctgggaactg cattcgaaac tggcaggctt gagtcttgta
      241 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt
      301 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac
      361 aggattagat accctggtag tccacgccgt aaacgatgtc tacttggagg ttgtgccctt
      421 gaggcgtggc ttccggagct aacgcgttaa gtagaccgcc tggggagtac ggccgcaagg
      481 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg
      541 atgcaacgcg aagaacctta cctggtcttg acatccacag aactttccag agatggattg
      601 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat
      661 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg
      721 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc
      781 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaa
//
LOCUS       DAJVKX010000297          827 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.300, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000297 DAJVKX010000000
VERSION     DAJVKX010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..827
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.300"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..742)
                     /gene="rfaJ"
                     /locus_tag="OPY25_004575"
     CDS             complement(<1..742)
                     /gene="rfaJ"
                     /locus_tag="OPY25_004575"
                     /EC_number="2.4.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase RfaJ"
                     /protein_id="HCS0929992.1"
                     /translation="MDSFPEIEIAEYKVFDESNNNDDNVLNISYGVDENYLDGVGVSI
                     ASVVLNNNIPLAFHIICDSYSPCFVKYIERLAVQHHIKISLYLIKVESLEVLPQTKVW
                     SRAMYFRLFAFDYLSKKVNTLLYLDADVVCKGSLQDLLQLDLTEKIAAVVKDVDSIQN
                     KVNERLSAFNLQGGYFNSGVVFVNLKLWKENALTEKAFLLLAGKEADSFKYPDQDVLN
                     ILLQDKVIFLPRPYNTIYTIKSELKDRSH"
BASE COUNT          284 a          152 c          127 g          264 t
ORIGIN      
        1 tatgtgacct atctttcaac tcacttttga tagtataaat ggtattatat ggtcgaggta
       61 gaaaaataac tttatcctgt aggagaatat tcaaaacatc ctgatcggga tatttaaaag
      121 agtcagcttc tttacctgcc agaagtaaaa atgccttttc agttaaggca ttctctttcc
      181 ataatttcag gttaacaaaa accacgccgg agttaaaata accaccttgt aaattaaaag
      241 cgcttaatct ctcatttacc ttattctgga tggaatcaac atcttttact accgcagcaa
      301 tcttctctgt cagatcaagc tgtagaagat cttgcaaaga tcctttacat acaacatcgg
      361 catccaaata aagtaaggtg tttaccttct tgctgagata atcgaaagca aataaacgaa
      421 aatacattgc tctcgaccat actttagttt ggggcaatac ttcaaggctt tctactttaa
      481 taagataaag agaaatttta atgtgatgct gtacggctaa acgctctata tattttacaa
      541 aacacgggga gtatgagtca caaataatat gaaaagcaag cgggatatta ttgtttaata
      601 caacggaagc gattgatacc cccacaccat caagatagtt ttcatcgacg ccataagaaa
      661 tgtttaatac gttatcatca ttattattac tttcatcaaa aactttatat tcagctatct
      721 ctatctcagg aaatgaatcc attacatcac ctatgggttt tattcaagaa gtttacgttt
      781 aaagtaggct atataataat ttatacccga agtataatgc ttctgat
//
LOCUS       DAJVKX010000298          825 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.301, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000298 DAJVKX010000000
VERSION     DAJVKX010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..825
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.301"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..>825)
                     /locus_tag="OPY25_004576"
     CDS             complement(<1..>825)
                     /locus_tag="OPY25_004576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCS0929993.1"
                     /translation="WTERAIAARDAGYEIHIISHFIGEEIIKKFKTLGFICHNVSLVA
                     QSFNMFVFFRAFLNARKIIKEINPDLLHCITLKPCLIGGVSARRSNSPVVISFVGLGR
                     IFLYNTVPMRILRALTVLVYKYIAGNKRGVFIFEHDKDRRKISRLVGIDYHKTIVIEG
                     AGINPDIYKFSIEKKHEIPIVLFASRMLWSKGLGDLIEAKKILRQKNIHFVLNVAGIL
                     AEDDKDAIPLELIHHWHNEGLINWLGRSSNVYELIQKSNIVALPSIYPEGVPRLLLE"
BASE COUNT          275 a          174 c          127 g          249 t
ORIGIN      
        1 ctctaataaa agccgtggta ctccttccgg ataaatagat ggcaatgcaa cgatattcga
       61 tttctgaata agctcatata cattcgaaga gcgtcccagc cagttaatta gtccttcatt
      121 atgccagtga tgaatgagct ccaaagggat agcatcttta tcgtcctcgg ccaatatacc
      181 tgcaacattt aaaacaaaat gaatattttt ttgtctgagg atcttttttg cttcaatgag
      241 atcgccaaga cctttactcc ataacattcg gcttgcaaaa aggactatcg gtatctcatg
      301 ttttttctct atagagaatt tataaatatc cgggttaatt ccagcacctt cgataacgat
      361 agttttatga taatcaatac ctactaaacg cgatattttt cgtcgatctt tatcatgttc
      421 aaaaataaaa acaccacgct tattaccggc aatatatttg taaaccaaaa cggttaacgc
      481 acgcaatatt ctcattggca cggtattata taaaaagatt cgaccaagtc cgacaaagct
      541 gataacaact ggactattac ttcttctggc gctaactcca ccaatcaggc aaggtttgag
      601 cgtaatacaa tgcaataagt caggattaat ctccttaata attttccgag cgttaaggaa
      661 tgctctaaaa aaaacaaaca tattaaatga ctgagcaaca agagacacat tgtgacaaat
      721 aaaaccaagc gttttgaatt tttttataat ctcttcacca ataaaatgac ttatgatatg
      781 aatttcataa cccgcatccc ttgccgctat cgcacgttct gtcca
//
LOCUS       DAJVKX010000299          806 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.302, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000299 DAJVKX010000000
VERSION     DAJVKX010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.302"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            103..765
                     /locus_tag="OPY25_004577"
     CDS             103..765
                     /locus_tag="OPY25_004577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCS0929994.1"
                     /translation="MKHTQQSGAKVYNPFTLSLYDWWVLNISNKYAWKCPTDTRLLPF
                     FLHHMGETHLDIGVGTGYYLKHAPATHAISLMDLNPDSLKIAASRVGNTKIRATLQHD
                     VFDTFPADWHGRFDSVSMYYLLHCLPGEMTTKAKAIKNAGMALKPGGTLFGATILGKE
                     VPHNAFGKKLMAVYNKKGIFSNTNDSADTLRSVLDEHFAKVTLEQHGAVALFSATMPR
                     SL"
BASE COUNT          217 a          195 c          181 g          213 t
ORIGIN      
        1 cctttattca tcgcattaaa ttactcactc acctgattaa tgcttgccta acgattactt
       61 cgttgtttta attccagcgc gaaattattt aatgagagaa caatgaagca tacacaacaa
      121 tcaggcgcaa aagtctataa cccattcacg cttagcttat atgactggtg ggtactcaat
      181 atctcaaaca aatatgcctg gaagtgtcct actgatacgc gactacttcc tttcttcctg
      241 catcacatgg gcgagactca cctggatatt ggcgtaggta caggttatta cctgaaacat
      301 gcacctgcga ctcatgccat ttcgctgatg gatttaaatc cggatagcct gaaaatagcc
      361 gccagccgag tgggtaatac gaaaatccgc gccacactac aacacgatgt tttcgacacg
      421 ttcccggcgg actggcacgg gcgcttcgat tccgtttcga tgtactatct tctgcactgc
      481 ttacccggtg agatgacaac aaaagcgaag gcaattaaaa atgccggtat ggcgctaaaa
      541 cccggcggca cactttttgg cgccacgatt ctgggcaaag aggttcctca caatgctttt
      601 ggtaagaaat taatggctgt ttataacaag aaaggaatat tcagtaatac caatgattca
      661 gccgatacgt tacgcagcgt gttggacgaa catttcgcta aggtgacttt ggagcaacat
      721 ggcgccgttg cgctattttc cgccactatg ccacgttcat tgtaggtgta ggcacttccg
      781 ggcggtcggc agcgcgatca tgtggg
//
LOCUS       DAJVKX010000300          806 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.303, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000300 DAJVKX010000000
VERSION     DAJVKX010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.303"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..436
                     /locus_tag="OPY25_004578"
                     /pseudo
     CDS             1..436
                     /locus_tag="OPY25_004578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343613.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          240 a          175 c          173 g          218 t
ORIGIN      
        1 gaaactcaca gctcttgcgg ctgaactggc taaaggtctt aaaactgaag ccgacctcag
       61 tcagtttttc catatgctga cgaaattaac cgtcgaaacg gcgctcaatg ctgagctggc
      121 tgaccatctc gggcatgaga aaaatgctcc taaaacgagc tcaaactccc acaatggcta
      181 ctcattaaaa acggtgctgt atgatggcgg cgagatagtg ctgaacatgc tgcgtggccg
      241 tgaaaatacc tttgaactgt agctgattaa ggagcatcag acgcgtatta cgagatggaa
      301 agtcagattt atccctttat gccaaaggca tgacatgact acccgcgaaa tcatcgccac
      361 cttcaaagag atgtacgacg ctgatgtgtc gcccatgctg atacttaaga tcaccgccgc
      421 agtaaaagag ttggtcaaag gggcgtcaaa aaatggagta tgccgatcca ggactggtcg
      481 ctggcaatga ttcgctttat tatcgagttc ggtgaccgcc tgagcgatca ccgttaatat
      541 agtggcagtt acacagtatg actggcatgt tccatattgg atttatatgt aatagtaaca
      601 gcctatctat ttgattattt tatttccaat tttattaaaa aggaaatcag aaccaggctt
      661 tgttaaatgt ccccaatcaa cggcagtgat aaaatcagga ccattaccaa ctcttgtaag
      721 acatccactt tcgttacata atgctttgta tgctgatata tattcaattc ccatttttgg
      781 aacattgtta ctaaagtaag agtccc
//
LOCUS       DAJVKX010000301          802 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.304, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000301 DAJVKX010000000
VERSION     DAJVKX010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.304"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            1..543
                     /locus_tag="OPY25_004579"
                     /pseudo
     CDS             1..543
                     /locus_tag="OPY25_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461634.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
     gene            547..802
                     /locus_tag="OPY25_004580"
                     /pseudo
     CDS             547..802
                     /locus_tag="OPY25_004580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461634.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
BASE COUNT          210 a          211 c          231 g          150 t
ORIGIN      
        1 caggtgatcc ctgaaaacga gggcggttgg tggatacgtg aagtgggcct gtttgatgag
       61 tccggggcat tgattgccgt gggaaactgc ccggaaagct ataagccgca actggctgaa
      121 ggcagcgggc gtacccagac cgtgcgcatg gtgctgatta ccagcagcac ggacaatatc
      181 accctgaaaa tcgaccctgc cgtagtgctg gcaacccgca agtatgtgga tgataaggta
      241 ctggagctga aggtgtacgt ggatgacctg atggcaaaac atcttgccgc accggacccg
      301 cattcacagt atgcacagaa agaaagtcct acgtttaccg ggacacccaa agcgccaacg
      361 ccagcggcgg ggaataacac cacgcaggtt gcgaccaccg cgtttgttca ggctgcactg
      421 acggctatta ttaatggtgc gccagccacg ctggacacgc tgaaagaaat agccgtagcc
      481 attaacaatg atccgaaatt cagtaccacc attaataatg cgctggcact gaaagcgccg
      541 ctgttgagtc cggcactcac cggaacgcca acagccccca cggcggcgca gtcggtcaac
      601 aatacacaga ttgccactac ggcttttgtg aaatcggcga ttgcggcaat ggtgggttct
      661 gcacctgcgg cactggatac actgaacgaa ctggcggcgg cgctggggaa tgacccgaac
      721 tttgccacga caatgcttaa tgcactggca ggtaaacaac cgctggacaa tacgctgact
      781 aatttgagtg gaaaggatgt ag
//
LOCUS       DAJVKX010000302          791 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.305, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000302 DAJVKX010000000
VERSION     DAJVKX010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.305"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            237..752
                     /gene="ompX"
                     /locus_tag="OPY25_004581"
     CDS             237..752
                     /gene="ompX"
                     /locus_tag="OPY25_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HCS0929995.1"
                     /translation="MKKIACLSALAAVLAFSAGTAVAATSTVTGGYAQSDAQGVANKM
                     SGFNLKYRYEQDDNPLGVIGSFTYTEKDRTNGAGDYNKGQYYGITAGPAYRLNDWASI
                     YGVVGVGYGKFQTTDYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
BASE COUNT          207 a          175 c          200 g          209 t
ORIGIN      
        1 attgatggat aaatagactg ttagtttagg aataatctgg atgaatgtat cgcgccacac
       61 gcgcattatt ggtgcaatca gccggaaaaa tgatgttaat tgaataagat agcgcgttat
      121 ggaaacgttc tgttacatga aaggcgccct tagacaccgt gaatcgcaaa gagtttccca
      181 ttaatttttg atatatttaa aacttaggac ttacttgaag cacatttgag gtggttatga
      241 aaaaaattgc atgtctttca gcactggccg ctgttctggc tttttccgca ggtactgcag
      301 tagctgctac ttctactgtt accggtggtt acgctcagag cgacgcgcag ggcgtagcga
      361 ataaaatgag cggtttcaac ctgaagtatc gttacgagca ggacgacaac ccgctgggtg
      421 taatcggttc cttcacctac accgaaaaag atcgtactaa cggtgcgggc gattacaata
      481 aaggtcagta ctacggcatc actgccggcc cggcttaccg tctgaacgat tgggcgagca
      541 tctacggtgt agtcggtgtg ggttacggta aattccagac gaccgattac ccaacctaca
      601 aacatgacac cagcgattat ggcttctcct atggcgctgg tctgcaattc aacccgatgg
      661 aaaatgttgc tctggacttc tcttacgagc agagccgtat tcgtagcgtt gacgttggca
      721 cctggattgc tggcgtaggt taccgcttct aatcacgtcg gtgaaaatga aaaatccgcc
      781 tttcggggcg g
//
LOCUS       DAJVKX010000303          787 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.306, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000303 DAJVKX010000000
VERSION     DAJVKX010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.306"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..598
                     /locus_tag="OPY25_004582"
     CDS             <1..598
                     /locus_tag="OPY25_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HCS0929996.1"
                     /translation="AETINSMNKYYDQDNFKDDAFAGAKAFHKTFIKQFDEFDPIAKK
                     YIAEITIMSKQHAANEIKATEKKEGKSIKYYTLLTMQEAETLNDAVADASFDVAAVSK
                     QLADFEEHTQKLNEKINVDIDKHRSFPGFISELEKFQGKVKKRIRRVRDNVAYTSHEQ
                     DYLNSGSGDMVDGSYKAVVKAYNELIDTYNGYHLEREF"
BASE COUNT          241 a          160 c          189 g          197 t
ORIGIN      
        1 agctgaaaca atcaatagta tgaataaata ctatgatcaa gataacttca aggatgatgc
       61 ctttgctggc gctaaagcgt tccataaaac gtttataaaa cagttcgatg agtttgatcc
      121 cattgcgaaa aaatatatcg ccgagattac cattatgagt aagcagcatg cggctaatga
      181 aattaaggcg accgagaaga aagaaggtaa atccattaag tactatacgc ttttgacgat
      241 gcaggaagcc gagacgctta atgacgctgt agctgatgct tcttttgatg tggcggcagt
      301 aagcaaacag ctcgctgatt ttgaagagca tactcagaag ctaaacgaga agatcaacgt
      361 tgatatagat aaacatcgta gcttccctgg ttttatttct gagctggaaa aattccaggg
      421 caaggtgaaa aaacgcattc ggcgcgtgcg cgataacgtg gcgtatacct cgcatgagca
      481 ggactacctc aatagcggca gcggcgatat ggtagatggt tcttataagg ctgtggttaa
      541 agcttataac gagctcatcg acacctataa tggctatcat cttgagcgtg agttctaagc
      601 ttttcacgct gcaaatcgcg tgcatatgac cgctgaactg agcaaataag tcgttaccga
      661 ctgtcgaaag agcgccccag gggcgctttt ttcgttcgaa gtattaccgg gtagcaagcg
      721 cctcgttaat gactggaata agctgcggtc cagcttaaaa acgattaaaa cctgtatggc
      781 ctcgcca
//
LOCUS       DAJVKX010000304          781 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.307, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000304 DAJVKX010000000
VERSION     DAJVKX010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..781
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.307"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(1..728)
                     /locus_tag="OPY25_004583"
                     /pseudo
     CDS             complement(1..728)
                     /locus_tag="OPY25_004583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460249.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cylase"
BASE COUNT          212 a          173 c          187 g          209 t
ORIGIN      
        1 tcctggttaa catccaccat cacgatgcct tttaacgatc ccgacagata gactggcgtt
       61 aaaaagctca tgacgttttc ctgggtaata tcatccatgt agatacttga aataaccgta
      121 cggccggtaa aaagtttatc tatatctttt ctgttaatac ccattgtgcc tttttgtaaa
      181 aaagtccaac gatgcatggc gaagcgccgt gagttgatta aatcatagaa atagacataa
      241 tgtttattta aatcaacgta ataacggaat ttaagctcca gtgtgcccag cccgtgactg
      301 tggtcgtcct gcgctcggtt gatgcttacc gcctgatcaa atgcaggcag taaaagggcg
      361 tcatcaagat tatcggtaca ctgtgtagcg acggtttgca gggtgccatg tagcgccgga
      421 taattatgcc gggtcaggtt gacgccgtgc gtaccgttaa tggcctcaaa ggcgtcgcaa
      481 aacgcgcggc gtttttctgc ggtgacgggg tctcccggcg cttcaaaagt tcgcatcaaa
      541 tgtgcggcga tgctttaatt ctggtactta tcgtacaaaa acgacgaatc ggctctctcc
      601 atgatataac gcatataggc attcattgcc ctgtcgctgg caataagttc gtaaatcagg
      661 aaggacgatg tcaaaacgat gacgcttgcc gagataaagt gcctgagcgc tttatgatgc
      721 aaattcatga tgaactacag ccctgaaagt cggatgcgtt agtttaccat agcgatgaga
      781 a
//
LOCUS       DAJVKX010000305          769 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.308, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000305 DAJVKX010000000
VERSION     DAJVKX010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.308"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..383)
                     /locus_tag="OPY25_004584"
     CDS             complement(<1..383)
                     /locus_tag="OPY25_004584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0929997.1"
                     /translation="MKWIIMVLVFSFSNVYAEDCSQQDFDKADMALDSLASWKAVDGF
                     YSRHSQCDVGYLREGTSEKIIRLLVDRWGELNELSALIKRKPALGDYVIDHIGEILDV
                     KDVEKIRDYSASHCQIDSKDLCKKL"
BASE COUNT          256 a          175 c          100 g          238 t
ORIGIN      
        1 tgcagttttt tacatagatc tttactatca atttggcaat gagatgctga ataatccctt
       61 attttttcaa catcttttac atcgagtatc tctccaatat gatcaataac ataatcgcca
      121 agtgctggtt tccttttgat aagcgcagat aactcattca attctcccca tctatccact
      181 aacaatctga taattttttc tgacgtgcct tcccggaggt agcccacatc acattgacta
      241 tgtcgggaat aaaagccatc gacagctttc catgacgcaa gagagtctaa cgccatatcc
      301 gctttatcaa agtcttgttg tgaacagtct tcagcataaa cattagaaaa agaaaaaact
      361 aaaaccataa ttatccactt catctaaagt atattctcat cgattgatta attccatatc
      421 cagtctgctc attatgaagc atcacacagt cgtaattaat gaaaaacatt cacccaatcc
      481 ccatcaatta atcacatgct atttaacctt gaatgagcga tatatttcct tataattatt
      541 aaataaggat gaatcgcctc taccaataaa aacaaacatt atgtttgttg acaatactat
      601 cactgcctga aagcactggt ctatatgata cccagcatca tctttgtacc tacatgaaac
      661 gattgcactc atgccaataa attttggcgt aatatttaca tcagctaaaa cagggacgcc
      721 atcagtaacg gcctcccatt ctccatcatc attctttgta aaaaaagaa
//
LOCUS       DAJVKX010000306          757 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.309, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000306 DAJVKX010000000
VERSION     DAJVKX010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.309"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..642)
                     /locus_tag="OPY25_004585"
     CDS             complement(<1..642)
                     /locus_tag="OPY25_004585"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HCS0929998.1"
                     /translation="MRVTIVLVAPARAENIGAAARAMKTMGFTDLRIVDSQAHLEPAT
                     RWVAHGSGDIIDNIEVFHTLADALHDVDFTVATTARSRAKFHYYASPAELVPLLQEKS
                     RWMRHAALVFGREDSGLTNDELALADVLTGVPMAADYPSLNLGQAVMVYCYQLAGLMQ
                     QTPESVDIADESQLQALRARLLRLLTTLEAADDHKLTDWLQQRIGLLGQRDTAM"
BASE COUNT          184 a          196 c          193 g          184 t
ORIGIN      
        1 cattgccgta tctcgctgtc ccagcaggcc gattcgctgt tgtagccagt cggttaattt
       61 gtggtcatcg gccgcctcca gagtggttag caggcgtaaa aggcgcgcgc gtaacgcctg
      121 taactgcgat tcatcagcaa tatcaacgga ttccggggtc tgttgcatta aacctgctaa
      181 ttgatagcaa tacaccatga ccgcctgacc cagattgagc gaagggtaat ccgccgccat
      241 cggcacgccg gtcaatacat ccgccagcgc cagctcgtcg ttggtcagac cggaatcctc
      301 acggccaaaa accagcgcgg catgacgcat ccagcgtgat ttttcctgta ataagggaac
      361 cagttcagcg ggcgaagcgt agtaatgaaa ttttgcccgg ctgcgggctg tcgtcgctac
      421 ggtaaaatcc acatcgtgga gcgcgtcggc aagggtgtgg aaaacctcaa tattatcaat
      481 aatatctcca gatccatgtg cgacccaacg ggtagcgggc tctaggtgcg cctggctgtc
      541 gacaatacgc aggtcagtaa atcccatggt cttcatagcc cgggcggctg cgccgatatt
      601 ttccgctctg gcgggagcga caagaacgat tgttacacgc atttcattac tctttttgac
      661 taatttacag gaaattagct ggcgtttgta agcatattac gcttcgcaaa tttacaaaat
      721 tttaacggat atcactgaaa aagcattttt gatttcg
//
LOCUS       DAJVKX010000307          737 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.310, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000307 DAJVKX010000000
VERSION     DAJVKX010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.310"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>737
                     /locus_tag="OPY25_004586"
     CDS             <1..>737
                     /locus_tag="OPY25_004586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCS0929999.1"
                     /translation="NNENLGGSGGFMRGLIEAGKINDVKHVIFMDDDGSCEIESICRT
                     HAFLLMAKDKNTVVTGCMLFEDNPAIIHESGAIWHRDFLHYPDKHYLDAREIDSLDTF
                     DNERKIGYGGWWFFAFNINAIEYYSFPFFVRGDDLLFGYMHKKHNIVTLNGVASWQMD
                     FERKISVLNSYLNFRTVAVPALISKRKFAALLLSVFFVREVFLASFSCRYELARAMIM
                     SYNDCLSGREFWEDNVDLLEIRKRINA"
BASE COUNT          219 a          106 c          164 g          248 t
ORIGIN      
        1 tcaataatga aaacctcggt gggtcaggcg ggtttatgag aggtttgata gaggcaggga
       61 aaatcaacga tgtcaaacat gtcatattta tggatgacga cggctcatgt gaaattgaat
      121 cgatttgtcg aactcatgct tttttactga tggctaaaga caaaaataca gttgttactg
      181 gctgtatgct ttttgaagat aacccggcaa tcatacatga atctggtgcc atatggcata
      241 gagatttttt acattacccg gataaacatt atctggatgc tcgggaaata gattctttag
      301 atacttttga taatgaaaga aaaataggct acggtggatg gtggtttttt gcctttaata
      361 ttaacgctat tgaatattac tcatttcctt tctttgttcg tggtgatgac ctgctatttg
      421 gatatatgca taaaaaacat aatattgtca cacttaatgg tgtggcttcg tggcaaatgg
      481 attttgaaag aaaaatatcg gttctaaata gctatttgaa cttcaggact gttgctgtac
      541 ctgcattaat tagtaaaaga aagtttgctg cactactgtt aagtgttttc tttgtgcggg
      601 aagtctttct tgcgagtttt tcatgccgct atgaacttgc cagagcaatg attatgtcat
      661 ataacgattg tctttctgga cgggagtttt gggaagataa tgtagatctt ctggagataa
      721 gaaaaagaat taatgca
//
LOCUS       DAJVKX010000308          735 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.311, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000308 DAJVKX010000000
VERSION     DAJVKX010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.311"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(42..>735)
                     /locus_tag="OPY25_004587"
     CDS             complement(42..>735)
                     /locus_tag="OPY25_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0930000.1"
                     /translation="INLHYHLENNLNSLEQTINIMNQSSLKKKFIIYSPQLLITQYAM
                     KLVKYIRKDPQVEIEHHDILTTDELPEDLLAYRKADVVVSMAPLNNRSIVCTHFNRLE
                     CILVCSENHPRLGDTATIDEILQESFTQLVSRATGMKEYHSLIDDVLGERIIGLRSKS
                     VMTIANSISSTELIGFLPQTFVDYYSSSIKLKKVATPFTIAPIQFYLMYNRASLNNSG
                     FAELIEYITKKR"
BASE COUNT          213 a          127 c          153 g          242 t
ORIGIN      
        1 tacacttaat ttatattatt actcgttctc tgatctcctt attaacgctt ttttgtgatg
       61 tactcaatga gctcagcaaa tccgctatta ttcagcgaag ctctattgta cataagatag
      121 aattgtatag gagcaatggt aaaaggtgtg gcgacttttt taagtttgat agaggaagag
      181 taatagtcaa caaatgtttg tggtaaaaaa ccaataagct ccgtggagct gatggagttg
      241 gcgatagtca tcaccgattt gcttcttaaa ccaattattc tctcccccag cacatcatct
      301 ataagtgaat gatactcttt cataccggtt gcccgggaga cgagttgcgt aaatgactct
      361 tgtagaattt catcgatagt ggcggtgtcg cctagtcggg gatgattttc actgcaaacc
      421 aggatacatt ctagcctatt aaagtgagta caaacaatag aacgattatt aagtggggcc
      481 attgaaacca caacatctgc tttgcggtag gcaagcagat cttcaggcag ttcgtcagtg
      541 gtcaaaatgt cgtgatgttc aatttcaacc tgtggatctt tgcggatata tttaactaat
      601 ttcatcgcat attgggtgat caacagctgt gggctgtaga taataaattt tttcttcaga
      661 ctggactgat tcattatatt aatagtttgt tccaggctgt taaggttatt ttctaaatga
      721 taatgtaaat taatg
//
LOCUS       DAJVKX010000309          721 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.312, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000309 DAJVKX010000000
VERSION     DAJVKX010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.312"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(91..183)
                     /locus_tag="OPY25_004588"
                     /pseudo
     CDS             complement(91..183)
                     /locus_tag="OPY25_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
     gene            450..721
                     /locus_tag="OPY25_004589"
                     /pseudo
     CDS             450..721
                     /locus_tag="OPY25_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461011.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="E3 ubiquitin--protein ligase"
BASE COUNT          257 a          154 c          121 g          189 t
ORIGIN      
        1 aataatcagc agaattacca aacaacccac tgttaattat aaaaatgata caattccaat
       61 aacacgtaat aatatttaaa agaaaacgat tatttcctga aaagcgattt cacgcgcttt
      121 acgcagttct ttttcatact cgccggaacg tccgccgacg atatcccgaa tgccggcgaa
      181 aaacgctggt tgagcgtcga agcgggttta tttttgcgtg catacgggct ccgttacccg
      241 acccgctctc ttatgcctgg atttttccgc agatacgcca gcgtcccaca atacggtgac
      301 atgatgacag gatggacact ttctgaaaga aacatgccag atagcatggt gaattgtgat
      361 ctccaacgcc ataccgacat atggagctta cttttaaggc gttaaaaatc cagaccgttt
      421 ttccataatg atgttgataa ggaattctaa tgaagatatc atcaggcgca attaattttt
      481 ctactattcc taaccaggtt aaaaaattaa ttaacaccat ccgtgaacat acgaaaaacg
      541 ggctcgcctc aaaaataacc agtgttaaaa atacgcatgc atctttaaat gaaaaattta
      601 aaacatgaaa ggactcaccg attgagatat cgctaccaca aaaaataaaa gaattctttc
      661 agccgaaaga aaaaatacct taaacaatac attgcttact gttaaaaata ttaaagatac
      721 a
//
LOCUS       DAJVKX010000310          718 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.313, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000310 DAJVKX010000000
VERSION     DAJVKX010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..718
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.313"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>718
                     /locus_tag="OPY25_004590"
     CDS             <1..>718
                     /locus_tag="OPY25_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HCS0930001.1"
                     /translation="QLKETTELYFKSMTQTLEPCLTKEKLIKYGIAIQELHGLQFDNE
                     QCVLLEHSPLKYTYNAANQSLLLNAPSKILSPIDSEIADENIWDDGINAFLLNYRANY
                     LHSKVGGEDSYFGQIQLGFNFGPWRLRNLSSWQNLSSEKKFESAYIYAERGLKKIKSK
                     LTVGDKYTSADLFDSVPFRGFSLNKDESMIPFSQRTYYPTIRGIAKTNATVEVRQNGY
                     LIYSTSVPPGQFEIGREQIAD"
BASE COUNT          250 a          122 c          132 g          214 t
ORIGIN      
        1 tcagttaaaa gaaactactg agttgtattt caaatcaatg actcagactc tagaaccatg
       61 cttaacaaaa gaaaaactta taaagtatgg gatcgccatc caggagcttc atgggttgca
      121 gtttgataat gaacaatgcg ttctcttaga gcattctcct cttaaatata cttataacgc
      181 ggctaaccaa agtttgcttt taaatgcacc atctaaaatt ctatctccaa tagacagtga
      241 aattgctgat gaaaatatct gggatgatgg cattaacgct tttcttttaa attacagagc
      301 taattatttg cattctaagg ttggaggaga agattcatac tttggtcaaa ttcaacttgg
      361 ttttaatttt ggtccctggc ggctaaggaa tctatcatct tggcaaaact tgtcaagcga
      421 aaaaaaattt gaatcagcat atatttatgc tgagcgaggt ttaaaaaaaa taaagagcaa
      481 actaacagtt ggggacaaat ataccagtgc agatttattc gatagcgtac catttagagg
      541 cttttcttta aataaagatg aaagtatgat acctttctca cagagaacat attatccaac
      601 aatacgtggt attgcgaaaa ccaatgcgac tgtagaagta agacaaaatg gatacttgat
      661 atattctact tcagtccccc ccgggcaatt cgagataggt agagaacaaa ttgctgat
//
LOCUS       DAJVKX010000311          707 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.314, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000311 DAJVKX010000000
VERSION     DAJVKX010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..707
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.314"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(90..295)
                     /locus_tag="OPY25_004591"
                     /pseudo
     CDS             complement(90..295)
                     /locus_tag="OPY25_004591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015364430.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          180 a          184 c          132 g          211 t
ORIGIN      
        1 agagttaggc tattttctaa tcactccggc agtctatgtt tcgatgttga ttgctggaga
       61 tttaccttcc ctatcatcac ctcctggctt cacttcatga tgctttccgg aacctttctg
      121 tacagcgtcg acagtctcac atcataaata atcgctacct gctgtcgcgg tacccctgcc
      181 ctcgctgcgc ccattgctcc ggggtgagct ttggacgtct gccaccaata cgcccctgct
      241 cccttgccgc tgccagcccg gcgcgggttc tttccacaat cagtaccctc tccatggtaa
      301 accgggtgga tacctcaaat tctgactggc cggataagcc agccagtcag tagtcgttac
      361 cgtgacaatt taattatcca tatatcacaa aatcacttgc ttacgcggta attaatccat
      421 ttggttaata aaaagttatt tcgtttacca gcatatttta ccccatggta gttctgggat
      481 taatgtatct ggcggccaga ttttacacca cggaaacgaa atacctggga atcctttatt
      541 accgctttca gtggccattg cagatgaaga aaatgttatg actgatatgg caaaaaccag
      601 cgctaacaat acactgttaa gtttattcat aatatcactc acataattga tagctatgct
      661 tcatccttaa cttttaccgc aatcctttta tcaggataaa gcagaaa
//
LOCUS       DAJVKX010000312          680 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.315, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000312 DAJVKX010000000
VERSION     DAJVKX010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.315"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..583)
                     /locus_tag="OPY25_004592"
     CDS             complement(<1..583)
                     /locus_tag="OPY25_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001539141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TioA protein"
                     /protein_id="HCS0930002.1"
                     /translation="MVKYHPVHVTKNRIKTDDVTDIYFVEPFWKKGENHIIESLMFFE
                     ELQKSFNLFNHKYGLNKYILRIPWEFVLIHMERISKLNSVGLFAVSVDFNNNHKFLSE
                     YIRSRRDYGMEVWFDFCGKHSYSSEIKNLGFFFQACVVPRDPNFISSVYHYHKFQKIL
                     VGDINDVEQRAVYQNEVDYMYGMQWPSSYDGFFF"
BASE COUNT          216 a          139 c          107 g          218 t
ORIGIN      
        1 gaaagaaaaa accgtcatat gacgatggcc attgcattcc atacatgtaa tcaacttcgt
       61 tctggtacac ggccctctgt tctacatcat ttatatcccc gacaagaatc ttttggaact
      121 tatgataatg ataaacacta ctaataaaat taggatcacg aggcactacg caagcctgaa
      181 aaaagaatcc aaggttttta atttcactgg aataagaatg tttaccacaa aaatcaaacc
      241 aaacttccat accataatct ctgcgactcc tgatgtactc gctcagaaat ttgtggttgt
      301 tattaaagtc aacagaaaca gcaaataacc cgacgctatt taatttactg atcctttcca
      361 tatgtatgag cacaaattcc caggggatcc tgagtatata tttatttaac ccatatttat
      421 ggttgaataa attaaatgac ttttgtaact cttcaaaaaa catcaatgac tcaattatgt
      481 ggttttcgcc ttttttccag aagggttcaa cgaaataaat atcagtaaca tcatctgttt
      541 taatgcggtt ttttgttaca tgcacggggt gatatttaac catgtgatat tccgctgtgt
      601 tattctgtgc cgcttaattt caccactgct gattaaaatc cttgttcaac agccgcaatc
      661 tgccgttgtt gttccgtaag
//
LOCUS       DAJVKX010000313          661 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.316, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000313 DAJVKX010000000
VERSION     DAJVKX010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.316"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..269
                     /locus_tag="OPY25_004593"
     rRNA            <1..269
                     /locus_tag="OPY25_004593"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            339..415
                     /locus_tag="OPY25_004594"
     tRNA            339..415
                     /locus_tag="OPY25_004594"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:373..375,aa:Ile,seq:gat)
     gene            527..602
                     /locus_tag="OPY25_004595"
     tRNA            527..602
                     /locus_tag="OPY25_004595"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:560..562,aa:Ala,seq:tgc)
BASE COUNT          168 a          155 c          177 g          161 t
ORIGIN      
        1 aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg actccatgaa
       61 gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc cgggccttgt
      121 acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc ttaaccttcg
      181 ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa ggtaaccgta
      241 ggggaacctg cggttggatc acctccttac cttaaagaag cgtactttgc agtgctcaca
      301 cagattgtct gatgaaaaac gagcagtaaa acctctacag gcttgtagct caggtggtta
      361 gagcgcaccc ctgataaggg tgaggtcggt ggttcaagtc cactcaggcc taccagattt
      421 tccctgaata ctgcgttgtg aaataactca catactgatg tatgcttcgt tattccacgc
      481 cttgtctcag gaaaaattat cggtaaagag gttctgacta cacgatgggg ctatagctca
      541 gctgggagag cgcctgcttt gcacgcagga ggtctgcggt tcgatcccgc atagctccac
      601 catctcgtga gtgtttacga aaaaatactt cagagtgtac ctgaaagggt tcactgcgaa
      661 g
//
LOCUS       DAJVKX010000314          661 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.317, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000314 DAJVKX010000000
VERSION     DAJVKX010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.317"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            19..>661
                     /gene="sseL"
                     /locus_tag="OPY25_004596"
     CDS             19..>661
                     /gene="sseL"
                     /locus_tag="OPY25_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector
                     deubiquitinase SseL"
                     /protein_id="HCS0930003.1"
                     /translation="MNICVNSLYRLSTPQFHSLYSEEVSDEALALLFSAVENGDQNCI
                     DLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKDN
                     TEWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCSARML
                     SSDELAAATLGLVQESPLLSVNYPIGLIHPTTKENILRTQLLEKMAQSGLSENE"
BASE COUNT          218 a          130 c          139 g          174 t
ORIGIN      
        1 accaggaaac agagcaaaat gaatatatgt gtaaattcac tttaccgatt gagcacaccg
       61 caatttcaca gtttatattc agaagaggtg agcgatgagg cgcttgcgtt gttgtttagc
      121 gccgtagaga acggtgatca gaattgtatt gatctgttat gcaatcttgc gttacgcaat
      181 gataacctgg gacatagagt tgagaaattt ctttttgatc tctttagcgg aaaaagatcg
      241 ggatcaccag acatagacaa aaaaatcaat caggcttgcc ttgtattaca tcaaatcgcc
      301 aataacgata taacaaaaga taatactgag tggaaaaagc tacatgcccc ttccagatta
      361 ctttatatgg ccggttccgc gacaaccgac ctttctaaaa aaataggaat agcacataaa
      421 attatgggcg accagttcgc tcagacagat caagaacagg taggagttga aaatctttgg
      481 tgtagtgcgc gaatgttgtc gtcagatgag ctagcagccg caacgctagg tctggttcaa
      541 gaatcacctc ttctctcggt aaactatcct attgggctta ttcatcctac caccaaagaa
      601 aatatattac gcactcagct acttgaaaag atggctcaat caggattatc tgaaaatgaa
      661 g
//
LOCUS       DAJVKX010000315          655 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.318, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000315 DAJVKX010000000
VERSION     DAJVKX010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..655
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.318"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            84..>655
                     /gene="pmrG"
                     /locus_tag="OPY25_004597"
     CDS             84..>655
                     /gene="pmrG"
                     /locus_tag="OPY25_004597"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II)-phosphate
                     phosphatase"
                     /protein_id="HCS0930004.1"
                     /translation="MLAFTLRFIKNKRYFAILAGALVIIAGLASQHAWSGNGLPQING
                     KALAALAKQHPVVVLFRHAERCDRSDNTCLSDSTGITVNGAQDARALGKAFSADIQNY
                     NLYSSNTVRTIQSATWFSAGRSLTADKKMMDCGSGIYASINTLLKKSQNKNIVIFTHN
                     HCLTYIAKNKRGVKFDPDYLNALVMYAENG"
BASE COUNT          166 a          144 c          167 g          178 t
ORIGIN      
        1 tatgtttctg gtcttccgtc gcggaatttc attttaatcg tattgctatt aagttagctg
       61 cactgtctgc ctgagaggtt aatgtgctgg catttaccct acgctttatt aaaaacaaac
      121 gctatttcgc gattctggcg ggggcgttgg ttattatcgc tgggttggcc tcacaacatg
      181 cctggagcgg taacggtcta ccgcagatta acggtaaggc gctggcggcg ctggcgaagc
      241 agcatccggt agtcgtgtta ttccgccatg ccgagcggtg cgatcgttcc gataatacct
      301 gcctgtcaga cagcacgggg attacggtca acggtgcgca agatgccaga gcgctgggta
      361 aagccttcag tgccgatata caaaattaca atctctattc cagtaatacg gtgcgcacca
      421 tccagtcggc aacctggttt tccgcaggca ggtcgcttac ggcggataaa aaaatgatgg
      481 attgcggcag cggtatttat gcttcaatca atacgttact gaaaaagtcg cagaataaaa
      541 atatagtcat ttttacccat aatcattgtt tgacgtatat tgcaaaaaat aagcgcggcg
      601 tgaagtttga tccggactat cttaatgcgc tcgttatgta tgcggaaaac ggaaa
//
LOCUS       DAJVKX010000316          648 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.319, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000316 DAJVKX010000000
VERSION     DAJVKX010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.319"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            7..549
                     /locus_tag="OPY25_004598"
     CDS             7..549
                     /locus_tag="OPY25_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012016429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HCS0930005.1"
                     /translation="MTKDEIFAAILSREGGYVDHPDDRGGPTHWGITLTTARANGYMG
                     DMRNLTRNQALKILEADYWYGPRLDQVAIISHSIAAELCDTGVNMGPSIPIKYFQRWL
                     NVFNDQQKIYPDLIADGQIGPRTLSALTFFLSHRRDEGEMILIRALNCSQGQRYLELA
                     EKRQANESFVYGWIKERVRL"
BASE COUNT          181 a          125 c          158 g          184 t
ORIGIN      
        1 gtcattatga ctaaagatga aatctttgca gctatcctta gtagagaagg cggttacgtt
       61 gatcaccctg acgacagggg ggggccaacg cattggggta taaccctgac gacggcccgg
      121 gctaatggct atatggggga tatgcggaat cttacccgta atcaagcatt aaaaatcctt
      181 gaggcagatt attggtatgg tccacgactt gatcaggttg ccattatctc tcactctatt
      241 gcagctgagc tttgtgatac tggtgtgaac atgggaccct caatcccgat taagtacttc
      301 cagcgttggc ttaatgtttt taatgatcag caaaaaattt atccggattt gatagcagat
      361 ggtcagattg ggccacggac gctttcggca ctaacatttt ttctctctca ccggagagat
      421 gagggcgaaa tgatacttat ccgggcattg aattgtagtc agggacaacg ctatctggag
      481 ttagctgaaa agcgccaggc gaatgaatca tttgtttatg gatggataaa ggaacgggta
      541 agattgtaat tcccttactt accactatag cggtttgtga tgatagcata taatgatata
      601 ttcacacaga gaactggtga aagccactaa gtctcattat tactatat
//
LOCUS       DAJVKX010000317          648 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.320, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000317 DAJVKX010000000
VERSION     DAJVKX010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.320"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..474)
                     /locus_tag="OPY25_004599"
     CDS             complement(<1..474)
                     /locus_tag="OPY25_004599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0930006.1"
                     /translation="MYIIRGDIIHIFEIRADDMYTTIRNTTLAMVACFSYIAHASTHP
                     PLIITRGAGGDASGAAVIHDNWRHGTPDLVNLTDIPIDKIRPEKYRCVLIIGQGAIKE
                     MLLANNASAILSGKTVGLYTHLIDQNTLRLLRQLQNKVRFNLFFTRSQITLLKLRN"
BASE COUNT          188 a          126 c          147 g          187 t
ORIGIN      
        1 gttccttagt tttagtagag ttatctgcga gcgggtaaaa aagagattga atctcacttt
       61 gttctgcaat tgccgaagta atctgagcgt gttctgatcg atcagatgag tataaagacc
      121 aacagttttt ccggaaagta ttgctgaggc attgttcgca agaagcatct cttttatagc
      181 tccttgccca ataatcagta cacaacggta tttttctggt ctgattttat ctatggggat
      241 atcggtaaga ttgaccaggt caggagtgcc atgccgccaa ttatcatgaa tgactgcggc
      301 tccggaggcg tctcctccgg ctcccctggt gataataaga ggagggtggg tactggcatg
      361 tgcgatatac gaaaaacaag ctaccattgc tagcgttgtg tttctgatgg ttgtatacat
      421 atcgtctgcc ctgatttcga aaatatgaat aatgtctcct cttataatgt acatcaaaaa
      481 gagaacattt aaattaaacg gtatctcaac gagataaaag gttagcacag taaagtatag
      541 agagaatgta atcataccaa cattgtaaat gtgggagcat gaaggccccg caagccgccc
      601 ggccagcata ctcccattaa tagttaaagt atggactttg cttttacc
//
LOCUS       DAJVKX010000318          639 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.321, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000318 DAJVKX010000000
VERSION     DAJVKX010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.321"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(139..639)
                     /locus_tag="OPY25_004600"
     CDS             complement(139..639)
                     /locus_tag="OPY25_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdiI family contact-dependent growth inhibition
                     immunity protein"
                     /protein_id="HCS0930007.1"
                     /translation="MTFIFDVNKEYHAGANLTDKFLCLETYSGLGRYSSDPDYPCQLL
                     SIDSDDVCIGHELLQALKNSRTYTPEESEEYLSLEKTQVEYDEWVTVLMAKYNYRTRR
                     ALFKNMKYCSIICVNNIIKIQPTRHTKLEGWSWAGHDKDVIRLPVTSEPEKIGSALRQ
                     AFECCD"
BASE COUNT          212 a          134 c           83 g          210 t
ORIGIN      
        1 ttaatatcca taggtaagca ataacaggga aaaaacatca aaaaaagcat aactattttt
       61 aacatcaatc agaccttaca acaattgtaa atttattgtc ttatttctat caaacataaa
      121 taacctatca tcaggctatt aatcacaaca ttcaaatgcc tgtctcaatg cacttccaat
      181 tttctctggt tcgctggtaa caggcaatct aattacatct ttgtcatgtc cggcccagct
      241 ccacccttca agtttagtat gtcgagtagg ttgtatctta ataatattat tcacgcatat
      301 aattgagcaa tacttcatgt ttttaaataa tgcacgcctg gttctataat tatattttgc
      361 catcaataca gtgacccact catcatactc cacctgtgtt ttctctaaag aaagatactc
      421 ttcactctct tctggggtgt aagttctgct attttttaat gcttgtaata attcatgacc
      481 gatacataca tcatccgaat caatagataa taactgacaa gggtaatcag gatctgaaga
      541 atagcgcccc aatcccgaat aagtttctaa acataaaaac ttatctgtca ggttagcacc
      601 cgcgtgatac tctttattta catcaaatat aaatgtcat
//
LOCUS       DAJVKX010000319          635 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.322, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000319 DAJVKX010000000
VERSION     DAJVKX010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.322"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            127..567
                     /gene="hpaR"
                     /locus_tag="OPY25_004601"
     CDS             127..567
                     /gene="hpaR"
                     /locus_tag="OPY25_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoprotocatechuate degradation operon regulator
                     HpaR"
                     /protein_id="HCS0930008.1"
                     /translation="MHDSLTIALLQAREAAMTYFRPIVKSHNLTDQQWRIVRILADSP
                     SMDFHELAFRTCILRPSLTGILTRMERDGLVLRLKPVNDQRKLYVMLTEQGQTLYARA
                     RSEVEEAYRKIEADFTPEKTQQLMLLLDDLIALGRQHPDSEAEA"
BASE COUNT          171 a          161 c          149 g          154 t
ORIGIN      
        1 tatatatcaa atagttaaat aaaacccctt gtttctgtta aactttggac ataaaacaga
       61 tgtcatagct cacatcggta aacacgatta ttcaggtatt aataattctg caaaagagaa
      121 acgcttatgc atgattcatt aaccatcgcc ttgcttcagg cgcgcgaagc ggcaatgacc
      181 tatttccgcc ccatcgttaa aagccacaat ctgaccgacc agcaatggcg cattgtgcga
      241 atcctggccg atagcccctc tatggatttt cacgagctgg cctttcgtac ctgtattttg
      301 cgtccaagtc tgaccggaat attgacgcgc atggagcgag acggactggt gttgcgactc
      361 aagccggtta acgatcagcg taagttatat gtcatgttga cggagcaggg acaaacgttg
      421 tacgcccgtg cccggagcga ggtagaagag gcttatcgaa aaattgaggc cgatttcacg
      481 cccgaaaaaa cacagcaatt gatgctgctg ctggacgatc ttattgctct ggggcgccag
      541 catcctgata gcgaagcgga agcatagtat tcttaccttc ccacgccgcc gacacgggaa
      601 tcccctcccg cttacaacgt tgacggcgat cgcat
//
LOCUS       DAJVKX010000320          627 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.323, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000320 DAJVKX010000000
VERSION     DAJVKX010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.323"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            49..300
                     /locus_tag="OPY25_004602"
     CDS             49..300
                     /locus_tag="OPY25_004602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0930009.1"
                     /translation="MPNNTKKTSSTIASQAAQVLKDPNASAIQKSLAGSALSQSGTSN
                     QTGGEMETTASKVLNSPKYNDQTKTLAASVLSQANKGRK"
BASE COUNT          225 a          115 c          108 g          179 t
ORIGIN      
        1 atgatactac atgctcaaaa ctgtaactct acataggtgc taatacatat gccaaataat
       61 actaagaaaa cctcctcaac gattgcatca caagcagctc aagtgctgaa agatcctaat
      121 gcttcagcta ttcagaaaag tttagccgga tctgctttat cccaatctgg gacttcaaac
      181 caaacgggtg gggaaatgga gactacagcc tcaaaagttt taaatagccc taaatataat
      241 gaccaaacaa agacgcttgc tgcttcagtt ctttcccaag ccaataaagg gcggaaatga
      301 cagcgtcttt atatctatag gcagctacat gtagctgctt ttcttctgat gattttaaat
      361 gtctacaatg gaaataattg tatggaacaa tgtaaaaatg acgctatatt agaacatatc
      421 aagaattata gtaaacatat tgatgaattt agatctcagg caaactcaca agggatttgg
      481 ttatttattt caactcttgg atgttggagc gtaaatatac cactaattca agttatcgcg
      541 gcaatcttgt tattctgcat atttatattt aattccaaac aggacatgac agaaaaaaga
      601 gcgtttcata aaatagaaga agacata
//
LOCUS       DAJVKX010000321          623 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.324, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000321 DAJVKX010000000
VERSION     DAJVKX010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.324"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            251..>623
                     /gene="spiC"
                     /locus_tag="OPY25_004603"
     CDS             251..>623
                     /gene="spiC"
                     /locus_tag="OPY25_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system protein SpiC"
                     /protein_id="HCS0930010.1"
                     /translation="MSEEGFMLAVLKGIPLIQDIRAEGNSRSWIMTIDGHPARGEIFS
                     EAFSISLFLNDLESLPKPCLAYVTLLLAAHPDVHDYAIQLTADGGWLNGYYTTSSSSE
                     LIAIEIEKHLALTCILKNVIRN"
BASE COUNT          194 a          103 c          133 g          193 t
ORIGIN      
        1 ttaataaggc agcgatgtaa aaacatcgta acagtttatt taataaataa tttttcaaat
       61 tgtaagtttt tgtgtctatg ctgaaaatgt aattgtgaat ttatcggaaa atccgaatga
      121 tagaatcgcc tgtgacaagg tatatgtaga cagcatcctg atattgtaca agaagagtat
      181 agtcgaaata aatgtgaatc aggcttttta cggatgtggt tgtgagcgaa tttgatagaa
      241 actcccattt atgtctgagg agggattcat gctggcagtt ttaaaaggca ttccattaat
      301 tcaggatatc agggccgaag gtaatagccg atcctggata atgactattg atgggcatcc
      361 tgccagagga gaaattttct cagaagcatt ttctatttct ttgttcttaa atgacctgga
      421 aagcttacct aagccttgtc ttgcctatgt gacactactg cttgcagcac acccggacgt
      481 ccatgactat gctatacagc tcacagcgga tgggggatgg ttaaacggtt attataccac
      541 aagtagtagc tctgagctta ttgctattga gatagaaaaa cacctggctt taacttgcat
      601 tttaaaaaat gtaatacgca atc
//
LOCUS       DAJVKX010000322          599 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.325, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000322 DAJVKX010000000
VERSION     DAJVKX010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.325"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>599
                     /gene="waaZ"
                     /locus_tag="OPY25_004604"
     CDS             <1..>599
                     /gene="waaZ"
                     /locus_tag="OPY25_004604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="3-deoxy-D-manno-oct-2-ulosonate III transferase
                     WaaZ"
                     /protein_id="HCS0930011.1"
                     /translation="DCIIFLSGPTSRKTPLSLLRMKDVIAVNGSVQYLLNNNVKPFLY
                     LLTDVRFLHRRREDFYNFSRNSQFTIVNLDVYEQASVDDQKYIEENCLIIRSFYRREK
                     GGFLKKIKFNILKRVHKALLISVPLSKRGRLAGFCKDISIGYCSYHTIAYTAIQVAYS
                     LKYGRIICSGLDLTGSCPRFYDESTSPMPSELSKDLFKI"
BASE COUNT          163 a          122 c          115 g          199 t
ORIGIN      
        1 aagattgtat tatttttctt tctggcccta cgtccagaaa gacgccgctg tccttgttac
       61 gaatgaaaga tgtcattgca gtcaatggtt ctgttcaata tttgctaaac aataacgtca
      121 agccattttt gtaccttctg acggatgttc gcttcctcca tcgccggcgc gaagattttt
      181 ataactttag ccgtaacagt cagtttacta tcgtcaatct tgatgtgtac gaacaggctt
      241 cagtggatga tcaaaaatat attgaagaaa actgtttaat tattcgctcc ttttatcgcc
      301 gagaaaaagg gggcttttta aagaaaatta aatttaatat cctcaagcgg gttcataaag
      361 cattacttat ttcagttcct ctttcgaaaa gaggacgact ggctggattt tgtaaggata
      421 tcagcatcgg gtattgctct taccatacta ttgcttatac cgctattcag gttgcctatt
      481 ccctcaagta tggccgtatt atatgttctg ggcttgactt aacagggagt tgcccacgtt
      541 tctatgacga atctaccagc cctatgccat ctgagcttag taaagacctg tttaaaata
//
LOCUS       DAJVKX010000323          565 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.326, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000323 DAJVKX010000000
VERSION     DAJVKX010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.326"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..305)
                     /locus_tag="OPY25_004605"
     CDS             complement(<1..305)
                     /locus_tag="OPY25_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 1"
                     /protein_id="HCS0930012.1"
                     /translation="MIVNLSRLGKSGTGMWQYSIKFLTALREIADVDAIICSKVHADY
                     FEKLGYAVVTVPNIVSNTSKTSRLRPLVWYVYSYWLALRVLIKFGNKKLVCTTHHTIP
                     "
BASE COUNT          206 a          113 c           77 g          169 t
ORIGIN      
        1 ggaatagtgt gatgcgtagt acacaccaat tttttattac caaacttaat taaaaccctc
       61 agcgcaagcc agtaactata tacataccat actaatggtc taagtcgcga tgtttttgat
      121 gtgttgctaa caatattcgg aacagtaact actgcataac cgagcttttc aaaataatca
      181 gcgtgtacct tgctacagat tattgcgtca acatcagcta tttctcgcag agccgttaaa
      241 aatttaatcg agtattgcca catccccgta ccgcttttac ctaaacgtga taggttaacg
      301 atcattgaat agctctccgt ttttccattc atgcttgtat agcgattatc acaagaacga
      361 ccaatagtta ttaggaaaca ttttcattaa aatgaaccac ggatcataat taaaaatgaa
      421 taaggaatca tatccaaata aatataagca agccttgtaa ttattataaa atcaccatta
      481 aaatcagttc ataatactaa gccaaatatt ataccaagta aaaatgccac aaaaaatagc
      541 atctgtcata atatactcac tctat
//
LOCUS       DAJVKX010000324          562 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.327, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000324 DAJVKX010000000
VERSION     DAJVKX010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.327"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            47..>562
                     /locus_tag="OPY25_004606"
     CDS             47..>562
                     /locus_tag="OPY25_004606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCS0930013.1"
                     /translation="MRKVSISILFMLVSLTWGTTWLAMRIAVETIPPVFATGMRFMFA
                     APFLIIIAWLRKKNLLFPPGQRLFQFVICIFYFSIPFSLMIYGETYVNSGLAAIIFAN
                     MPVAVLIASVLFLNEKAKLMQIAGLTIAITALTGILLEETNTSTESHWQGITALISAV
                     LIHAIIYTQCKK"
BASE COUNT          152 a          107 c          112 g          191 t
ORIGIN      
        1 ttttctagct aaaaagctaa attaattttt ttatggagag gatcttatgc gcaaggtgtc
       61 gatatctata ttattcatgc tagtttcact gacctggggg actacatggt tggctatgcg
      121 aattgccgtt gaaactatcc ctccagtgtt tgcaaccgga atgaggttta tgtttgcagc
      181 acctttttta atcatcattg catggttaag aaaaaaaaac ctgttgtttc ctcccggaca
      241 acgattattc cagtttgtga tttgcatctt ttatttttct attcctttct cactaatgat
      301 ttatggtgaa acctatgtca actctgggct tgccgccatt atctttgcga atatgcctgt
      361 ggccgttttg atagcatcgg ttttgtttct aaatgaaaaa gcgaaactaa tgcagatcgc
      421 gggcttaact atcgcaatca ctgcattgac ggggatactt cttgaagaaa cgaatacaag
      481 tacagagagt cactggcagg gtatcactgc gcttatttct gctgtgttaa tccatgccat
      541 aatatataca caatgtaaga aa
//
LOCUS       DAJVKX010000325          551 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.328, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000325 DAJVKX010000000
VERSION     DAJVKX010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.328"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(117..>551)
                     /locus_tag="OPY25_004607"
     CDS             complement(117..>551)
                     /locus_tag="OPY25_004607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0930014.1"
                     /translation="HRGSKIKLEIYNETDMASASGYTPVPSVSEFQYIETETISNTPS
                     PDLTVMSIDKPVLSPGESATITTIVKDIDGNPVNEVLIDKTVKYENSKGLWDYGPIKK
                     ENVPGKYTQVITYRGHSNERIDISFEYAGDLFRKEISIRGRL"
BASE COUNT          167 a          102 c           86 g          196 t
ORIGIN      
        1 ttgtattatt ttagccataa taattattta gcaatccgct aaaaaaccag gtgaacatcc
       61 ataataagat gatggtgata aaaagaatta tattagccat aatgattaat atagttttat
      121 agtcttcctc tgatggaaat ttctttcctg aacaaatccc ctgcatattc aaaagatatg
      181 tcaatacgtt cgttactatg tccacgatag gttataactt gtgtatattt acctggcaca
      241 ttttctttct taatagggcc ataatcccat aagccttttg aattttcata ctttacagtc
      301 ttatcaatga gaacttcatt tacaggattt ccgtcgatat ccttaacaat agttgtgatg
      361 gtggcacttt cacccggcga taatacaggt ttatctatac tcataactgt taaatctggg
      421 cttggcgtat tagatatagt ttctgtttca atatactgaa attcagatac cgatggcaca
      481 ggcgtgtacc ctgacgctga agccatatcc gtttcattat aaatttctag tttaatcttt
      541 gaaccccgat g
//
LOCUS       DAJVKX010000326          547 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.329, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000326 DAJVKX010000000
VERSION     DAJVKX010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.329"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
BASE COUNT          218 a           99 c           76 g          154 t
ORIGIN      
        1 ctacctttaa gacgtcacat caaaggcatt tcagtatccc cattcaacat ttatacggag
       61 tatttaaaat cttaggagat agtcatatct atttttatag gtccaatcaa gcctgcccgg
      121 actgtacagt accggcatta aaagaaatat cacatggctc tccgttggat atagatgaac
      181 acaattaatt gagcataacg aaacaacaac tcctataaag cacttataac aaccacacat
      241 ggcttacact gtatttagat attttaaaac atcatcttcg gctaatcata tctaataaag
      301 ttatttttat atcataaaac aatacctaca ataatataaa atcggcttct gcagtgaagc
      361 gtaaaaatta ggtgcaattc catgctgaaa aaaaacgcca taaaaataaa actatatcgt
      421 tatgctattt tacattcgaa aaactgtatt attaccatta agaacaagtc aaagccagag
      481 gaaataaaaa taactagagg caacatagcc ttaatagaaa aaatatagaa gctgttgtgg
      541 aaattga
//
LOCUS       DAJVKX010000327          542 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.330, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000327 DAJVKX010000000
VERSION     DAJVKX010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.330"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>542
                     /gene="siiD"
                     /locus_tag="OPY25_004608"
     CDS             <1..>542
                     /gene="siiD"
                     /locus_tag="OPY25_004608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiD"
                     /protein_id="HCS0930015.1"
                     /translation="KGGTIQDIYVAEGDTVKKGELLAKVVNFDLQKEYQRYRTQKGYL
                     DKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEI
                     SGLQEKLSSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESS
                     ITLKKDDIELVVNDIEALNN"
BASE COUNT          215 a           71 c          112 g          144 t
ORIGIN      
        1 ctaaaggagg gacgatacaa gatatttatg tggccgaggg ggatactgta aaaaaaggag
       61 aactccttgc aaaggtcgtt aactttgatc tgcaaaaaga atatcaaagg tatagaactc
      121 aaaaagggta tctggataaa gatgttaacg aaatatcttt cattcttgat aaagaaaatg
      181 agagtggatt gattaccctg gatggcaccc gttctttaag caacaaagag gtaaaagcga
      241 atattgaatt agtgcatagt cagataagag ctaaagagtt aaaaaaaacc tctcttgatt
      301 ctgagattag cggattacaa gagaagctaa gttcgaaaga aaaagaacta gcattgcttg
      361 ccgaagaaat aaatattctt tctccactgg taaaaaaagg aattagccca tataccaatt
      421 ttcttaacaa gaaacaggcg tatataaaag ttaagtctga aattaatgat attgaaagta
      481 gcatcacttt aaaaaaagat gatattgagc tggttgttaa tgatattgag gcgcttaata
      541 at
//
LOCUS       DAJVKX010000328          541 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.331, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000328 DAJVKX010000000
VERSION     DAJVKX010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.331"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..>541)
                     /locus_tag="OPY25_004609"
     CDS             complement(<1..>541)
                     /locus_tag="OPY25_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCS0930016.1"
                     /translation="FSERLPSAMGAYWQVYIAFIILLISVVLSRNSSSKLMFGSFLFI
                     LGAIAANVAFLASPAMPSRALNGALCFMILSISFVAHSAFTKFNKASIYLSITTYAMA
                     FLYFIPSYILYYSSIKSISKQTEIREEIIDRAKDNKQDQAIIPDYYFPPVLHAGPSLD
                     TFNSEAMSRYYGIDVKITAP"
BASE COUNT          176 a           95 c          106 g          164 t
ORIGIN      
        1 tggagcagtt atttttacat caatcccgta gtatctagac attgcttcac tgttaaacgt
       61 atcaagactt gggcctgcat gcagtaccgg tggaaagtaa taatcaggaa ttatcgcttg
      121 atcttgtttg ttatctttcg ccctgtctat tatttcttcc ctaatctccg tttgtttgct
      181 tattgattta attgatgagt aatagagaat gtatgatgga atgaaatata aaaaagccat
      241 tgcatatgta gtaatagata aataaatgga agctttgtta aatttcgtaa atgcagaatg
      301 agcaacaaag gaaatcgaaa gaatcataaa gcagagtgct ccattgagag ccctgctggg
      361 cattgcagga gatgcaagga acgcaacatt tgcagcaatt gcacccagta tgaataaaaa
      421 gcttccaaac ataagtttgc tgctactatt ccttgataac actacagaga ttagtagtat
      481 tataaatgca atatagacct gccaatatgc ccccattgct gatggcagcc tttctgaaaa
      541 g
//
LOCUS       DAJVKX010000329          529 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.332, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000329 DAJVKX010000000
VERSION     DAJVKX010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.332"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            283..519
                     /gene="lpp"
                     /locus_tag="OPY25_004610"
     CDS             283..519
                     /gene="lpp"
                     /locus_tag="OPY25_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HCS0930017.1"
                     /translation="MNRTKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNQATKYRK"
BASE COUNT          158 a          117 c          106 g          148 t
ORIGIN      
        1 aaaaagcgcc cttccggcgc ttttttattt aatcgatagc cactattaat aaaaaaatca
       61 aatcggattt tactatctaa ttgcggatta tctaagaaga atccgatgga agccccctgt
      121 tttctttcgg ttttttaggg actttcatgc atttcgatgc ttctttgagc gaacgatcaa
      181 aaataagtgc attcccatca aaaaaatatt ctcaacataa aaaagtttgt gtaatacttg
      241 taacgctaca tggagattaa ctcaatctag agggtattaa taatgaatcg tactaaactg
      301 gtactgggcg cggtaatcct gggttctact ctgctggctg gttgctccag caacgctaaa
      361 atcgatcagc tgtcttctga cgttcagact ctgaacgcta aagttgacca gctgagcaac
      421 gacgtgaacg caatgcgttc cgacgttcag gctgctaaag acgacgcagc tcgcgctaac
      481 cagcgtctgg acaaccaggc tactaaatac cgtaagtaat agtacctgc
//
LOCUS       DAJVKX010000330          524 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.333, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000330 DAJVKX010000000
VERSION     DAJVKX010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.333"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>524
                     /locus_tag="OPY25_004611"
     CDS             <1..>524
                     /locus_tag="OPY25_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCS0930018.1"
                     /translation="FIEDLLESINNQSSHSLIVEVCISDNASTDGTEESINIWRDRFN
                     FPILYQRHNENIGPDRNYLSAVNMGTGDYCWIFGSDDILTKNSLALMEDKLAAGSDIY
                     LCDRRELDISMTKISNPHRRWLNGGSRLFSFSNEADLIEYFSKCNSVGGLFSYLSSII
                     VKRNKWSDVLFDES"
BASE COUNT          175 a           68 c          104 g          177 t
ORIGIN      
        1 ttcattgaag accttcttga aagtattaat aatcaatctt ctcactcctt aattgtagaa
       61 gtatgtattt cagataatgc atcaactgat ggaactgaag aatcaataaa tatctggaga
      121 gatagattta attttccaat tttatatcaa aggcataacg aaaatattgg gccagatagg
      181 aattatttat ctgcagttaa tatggggact ggagattatt gttggatttt cggaagtgat
      241 gatattctta caaaaaattc ccttgcattg atggaagata aattggctgc cggaagtgac
      301 atttatttat gtgacagacg agaattagat atttcaatga cgaaaatatc taatccacat
      361 cggcgatggt taaatggtgg cagtagatta ttttctttta gcaatgaagc tgatttgata
      421 gagtacttta gtaaatgtaa ctcagtcggc ggacttttta gctacttaag ctctattata
      481 gtgaaaagga ataaatggtc tgacgtctta tttgacgagt cata
//
LOCUS       DAJVKX010000331          504 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.334, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000331 DAJVKX010000000
VERSION     DAJVKX010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.334"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            125..>504
                     /locus_tag="OPY25_004612"
     rRNA            125..>504
                     /locus_tag="OPY25_004612"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          140 a          107 c          150 g          107 t
ORIGIN      
        1 gacaatctgt gtgggcactc gaagatacgg attcttgacg tcgcaagacg aaaaatgaat
       61 accaagtctc aggagtgaac acgtaattca ttacgaagtt taattctttg agcatcaaac
      121 ttttaaattg aagagtttga tcatggctca gattgaacgc tggcggcagg cctaacacat
      181 gcaagtcgaa cggtaacagg aagcagcttg ctgctttgct gacgagtggc ggacgggtga
      241 gtaatgtctg ggaaactgcc tgatggaggg ggataactac tggaaacggt ggctaatacc
      301 gcataacgtc gcaagaccaa agagggggac cttcgggcct cttgccatca gatgtgccca
      361 gatgggatta gcttgttggt gaggtaacgg ctcaccaagg cgacgatccc tagctggtct
      421 gagaggatga ccagccacac tggaactgag acacggtcca gactcctacg ggaggcagca
      481 gtggggaata ttgcacaatg ggcg
//
LOCUS       DAJVKX010000332          502 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.335, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000332 DAJVKX010000000
VERSION     DAJVKX010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.335"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..>502)
                     /locus_tag="OPY25_004613"
     CDS             complement(<1..>502)
                     /locus_tag="OPY25_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HCS0930019.1"
                     /translation="FALTIPVFSNLFYDKLVPSASVSSLFGVAIIVAVFIVFEFILRT
                     SKDIYQSITARQDDVDIDIAFLEAVLYSKKKNGRSMSSAFVLWNEFQKIKPVLLNSIF
                     QRIADIPIFIIFLIVIYVNLGLVVIVPVTMFIVSIIIFLVNHHYTNELMNKQKEGQKN
                     RNIFIS"
BASE COUNT          191 a           84 c           81 g          146 t
ORIGIN      
        1 tctgagataa aaatattcct gttcttctgt ccttcttttt gtttgttcat taactcatta
       61 gtataatggt ggttaacgag gaaaataata atagagacga taaacatggt aacaggtaca
      121 ataacgacca gacctaaatt tacatatata acaatgagaa atataataaa tattggaata
      181 tcggctatac gttgaaagat cgagtttaat aaaacgggtt taattttctg aaactcattc
      241 catagcacaa atgctgatga catggatctg ccatttttct ttttactata aagtaccgct
      301 tcaagaaatg cgatatcaat atcgacgtca tcctgccttg ctgtgataga ctgataaata
      361 tctttcgaag tacgaaggat aaactcaaaa acaataaata cagcaacaat tatagccacg
      421 ccaaataacg atgaaaccga agcgcttgga acaagcttat catagaacag attactaaat
      481 actgggatag ttaacgcaaa aa
//
LOCUS       DAJVKX010000333          501 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.336, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000333 DAJVKX010000000
VERSION     DAJVKX010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.336"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..129
                     /locus_tag="OPY25_004614"
     CDS             <1..129
                     /locus_tag="OPY25_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HCS0930020.1"
                     /translation="LLKNPQIRLEMGANGRKRVKELFSSILVINKTLQIYKDTIGC"
     gene            258..>501
                     /locus_tag="OPY25_004615"
     CDS             258..>501
                     /locus_tag="OPY25_004615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCS0930021.1"
                     /translation="MNDLKEALAKHQLWISLGWNDVLGRYRRSVLGPFWITISMGVTI
                     SAMGPLYGSLFSSGSENFIMHLTLGMIFWAFLSATIN"
BASE COUNT          159 a           75 c          108 g          159 t
ORIGIN      
        1 ttgttaaaaa atccacagat tcgcttagag atgggggcga atggaagaaa acgtgtaaag
       61 gaattgtttt ccagcatatt agtcattaat aagacattgc aaatttataa agacactatt
      121 ggttgctaac accataaaat gcttatgaag taggtcagtg tttagataaa tagtatgtaa
      181 atattataga aaataaataa gttatatttt catatcgtta aagaataagt tcttcaggta
      241 aaggtgacac ggaaacaatg aatgatttga aagaagctct ggccaagcac caactttgga
      301 tttcgctagg ttggaatgat gtcctgggac gataccggcg atcggtgtta gggccttttt
      361 ggataacgat ttcgatggga gtcaccatat cagcaatggg acctctttac ggttcgctgt
      421 tcagttctgg ttccgaaaat tttatcatgc atcttacttt aggtatgatc ttttgggcct
      481 ttctatcagc aactattaat g
//
LOCUS       DAJVKX010000334          500 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.337, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000334 DAJVKX010000000
VERSION     DAJVKX010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.337"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..269
                     /locus_tag="OPY25_004616"
     rRNA            <1..269
                     /locus_tag="OPY25_004616"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            355..430
                     /locus_tag="OPY25_004617"
     tRNA            355..430
                     /locus_tag="OPY25_004617"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:389..391,aa:Glu,seq:ttc)
BASE COUNT          124 a          122 c          140 g          114 t
ORIGIN      
        1 aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg actccatgaa
       61 gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc cgggccttgt
      121 acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc ttaaccttcg
      181 ggggggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa ggtaaccgta
      241 ggggaacctg cggttggatc acctccttac cttaaagaag cgtactttgc agtgctcaca
      301 cagattgtct gatgaaaagt gaatagcaag gcgtcttgcg aagcagactg atacgtcccc
      361 ttcgtctaga ggcccaggac accgcccttt cacggcggta acaggggttc gaatccccta
      421 ggggacgcca cttgcgcggt aatgtgtgaa aggcgttgcc atcagtatct caaaactgac
      481 ttacgagtca cgtttgagat
//
LOCUS       DAJVKX010000335          500 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.338, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000335 DAJVKX010000000
VERSION     DAJVKX010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.338"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..>500)
                     /locus_tag="OPY25_004618"
     CDS             complement(<1..>500)
                     /locus_tag="OPY25_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector NleG family protein"
                     /protein_id="HCS0930022.1"
                     /translation="LTFPNVAITRDNRIDKLSENDLELIRDTAIQNGGRKIQVQLRDL
                     LYEVSNRAVEGDNNTFKVSFSTTDRAMFRERHIEWQGNAIRLERQLNTGLNVSRGNFL
                     NMSTTSFSNNSQELAAHSSPGAPAIFDTSNKQQLVDKIDLCSFSPNVDELSCTEDNLT
                     CPVMLVV"
BASE COUNT          148 a           98 c           80 g          174 t
ORIGIN      
        1 acaactaaca ttaccgggca tgttaagttg tcttccgtac atgaaagttc atcaacattt
       61 ggtgagaaac tgcataaatc aatcttatcc actaattgtt gtttattaga tgtatcaaaa
      121 atagcaggtg ctcctggtga actgtgggct gctaactcct gactgttatt ggaaaatgat
      181 gtggtcgaca tatttaaaaa atttccacgc gacacattca gtccagtatt taattgtcgt
      241 tctaacctta tagcgtttcc ctgccattca atatgacgtt ccctaaacat ggctcggtct
      301 gtagtagaaa aactaacttt gaatgtatta ttatcacctt caacagcacg attacttact
      361 tcatataata aatcacgtaa ttgtacctgt atctttcttc cgccattttg tatagccgta
      421 tcacgaatga gttctaaatc attttcagat aatttgtcta tcctgttatc tcgagttatt
      481 gctacattag gaaatgttaa
//
LOCUS       DAJVKX010000336          489 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.339, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000336 DAJVKX010000000
VERSION     DAJVKX010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.339"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>489
                     /locus_tag="OPY25_004619"
     CDS             <1..>489
                     /locus_tag="OPY25_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4765 family protein"
                     /protein_id="HCS0930023.1"
                     /translation="VKISLNYSYENIDGGRGCLSLPFDQNGYPIPPDFHNCVNGITSK
                     KMLLDLFLKHILHDHLNASGEVANVYANVIYKEIDPAAIAHTSSCFSQVTMSGEHELF
                     NVDSVTVPPKSTEQIIFEGKEIQKQIFLSSHSRNHLQPVTIHKMDRSIKNIAVTGLLL
                     SS"
BASE COUNT          165 a           86 c           88 g          150 t
ORIGIN      
        1 aggtaaagat atctctaaat tacagttacg aaaatattga tggggggcga ggatgtttat
       61 cgcttccatt tgatcaaaac ggctatccaa ttccccctga ctttcacaac tgtgtaaatg
      121 gaatcacatc aaaaaaaatg ttgttagatc tatttctaaa acatattttg cacgatcatt
      181 taaatgcaag cggtgaagtt gcaaacgttt acgccaatgt tatttataaa gagattgatc
      241 ccgctgcaat tgcacataca tcgtcgtgtt tttctcaggt aacgatgagt ggtgaacatg
      301 agctatttaa tgtagatagc gtaactgttc cacctaaaag cactgagcaa attatatttg
      361 agggaaagga aattcaaaag caaattttct tatcttctca tagccgcaat catcttcagc
      421 cagtaaccat tcataaaatg gacaggagta ttaaaaacat tgcagtaact ggtttgttat
      481 tatcatcaa
//
LOCUS       DAJVKX010000337          484 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.340, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000337 DAJVKX010000000
VERSION     DAJVKX010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.340"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
BASE COUNT          143 a          115 c           97 g          129 t
ORIGIN      
        1 atgaatagac ggcaggaaaa accgtgagtg tctcacaccg attcttgctg gatgtcaaat
       61 ttcgaaagcc tgccctgctg ataccctatc aagaagaaac taacccaaca attatcagac
      121 agtagcagga atcgaaccca caccaggcaa atcacgtaga taattctgta agggttagtt
      181 ttgtggtggt cttgataaac ggtaaaaaat agctttaaca gtccattagc ccaaaggact
      241 tctccgagtc cgggctccaa ccattcagat gcggacgccc tatggcgtcc gtttttattt
      301 ataaaatcaa caggttaccc cgcccttcat gttcactact gttcattaaa atatactggc
      361 agccaccgct ttttgtgggt aaaaacgccg gttttctgca tagcgcatga cgctattgaa
      421 acgttattta gcaaatcctg tctgagccag aaattaagtc tctgttaacc tgcgctatta
      481 caga
//
LOCUS       DAJVKX010000338          471 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.341, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000338 DAJVKX010000000
VERSION     DAJVKX010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.341"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            8..>471
                     /locus_tag="OPY25_004620"
     CDS             8..>471
                     /locus_tag="OPY25_004620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000382485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF943 family protein"
                     /protein_id="HCS0930024.1"
                     /translation="MLFCSVVIYLWSGRPVEIVDVHYYSGKDINILARHFPITDRGKL
                     NWWRENERKILEKYNLPKNNFSVYIWDFGDGYQKLSPYDAEDEFYCFPDIKSESKCIK
                     KDIYMPAESGGNYYRMFLFSGSGYFYQPKKDDDKLIESNNSTKLNQDKSHEK"
BASE COUNT          165 a           69 c           86 g          151 t
ORIGIN      
        1 aatcgccata ttattttgtt ctgttgttat atacttatgg tcaggcagac cagtagaaat
       61 cgtggatgtc cattattatt caggtaaaga cattaacatt cttgccaggc atttccccat
      121 tacggacagg ggaaagctga attggtggag agaaaatgaa agaaaaattc tggaaaaata
      181 taatctccct aaaaataatt tttcggtata tatatgggat tttggtgacg gttatcaaaa
      241 attatcgccc tatgatgccg aggatgaatt ttattgtttt cctgatataa aatcagaatc
      301 aaaatgtatc aaaaaagata tatatatgcc tgctgaatct ggtggtaatt attatcggat
      361 gtttttattt tctggttctg gttattttta tcaaccgaaa aaagatgatg ataagcttat
      421 cgaatcaaat aactccacca agctcaacca ggataaaagc catgaaaaaa a
//
LOCUS       DAJVKX010000339          464 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.denovo.342, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000339 DAJVKX010000000
VERSION     DAJVKX010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.denovo.342"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..>464
                     /locus_tag="OPY25_004621"
     CDS             <1..>464
                     /locus_tag="OPY25_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylneuraminic acid mutarotase"
                     /protein_id="HCS0930025.1"
                     /translation="NAGELPGAGTAGSSSVMENNFLMLINGELKPGLRTDVIYRAMWD
                     NDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYS
                     HEGINKKWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKG"
BASE COUNT          133 a           80 c          133 g          118 t
ORIGIN      
        1 agaatgccgg tgagctgcca ggcgcgggga cggcaggatc gtcatcggta atggaaaata
       61 atttcttgat gctgattaat ggtgagctca aaccgggttt acgtaccgat gtgatttacc
      121 gcgccatgtg ggataacgat aagctaacat ggttgaagaa cagccagtta ccgccatcgc
      181 ctggagaaca acagcaggaa gggttggccg gagcattttc gggctatagc cacggtgtcc
      241 tgcttgtcgg tggtggcgcg aattttccgg gagcaaaaca aaattatact aatggaaagt
      301 tttattccca cgaagggata aataaaaaat ggcgagatga agtctatggt ttgattaatg
      361 gccattggca atatatgggt aaaatgaaac aacctctcgg ctatggtgta tcagtaagtt
      421 atggtgatga agttttcctt attggtggtg aaaatgctaa aggg
//
LOCUS       DAJVKX010000340         3542 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.guided.235, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000340 DAJVKX010000000
VERSION     DAJVKX010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.guided.235"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..404
                     /locus_tag="OPY25_004622"
     CDS             <1..404
                     /locus_tag="OPY25_004622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HCS0930026.1"
                     /translation="GTLLWICTSPYRPHHGRKNWYVGIGRFSADEHIQSDEIRFETLR
                     SSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLLIAWRLEQQRQNEC
                     AALKSERRLFHHQIERGNPLRIFKGMAFTPQ"
     gene            complement(559..2016)
                     /gene="pepD"
                     /locus_tag="OPY25_004623"
     CDS             complement(559..2016)
                     /gene="pepD"
                     /locus_tag="OPY25_004623"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HCS0930027.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEHIVSWAKEKG
                     LYVDRDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNSDTVHDFTTDPIRPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADDNVVHGPLEVLLTMTEEAGMDGAFGLQSGWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLPLTREAVPAGFACFKLTLKGLKGGHSGG
                     EIHLGLGNANKLLARFLAGHAEELDLRLIDFNGGTLRNAIPREAFATLAVATDNVGAL
                     KTLVNAYQDILKNELAEKEKNLTLQLNEVASDKAALTAPSRDTFVRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMSDANVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGSYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPDMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKAIPAK"
     gene            2265..2723
                     /gene="gpt"
                     /locus_tag="OPY25_004624"
     CDS             2265..2723
                     /gene="gpt"
                     /locus_tag="OPY25_004624"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCS0930028.1"
                     /translation="MSEKYVVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            2812..>3542
                     /locus_tag="OPY25_004625"
     CDS             2812..>3542
                     /locus_tag="OPY25_004625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCS0930029.1"
                     /translation="MTQANLSETLFKPRFKHTETSTLVRRFNRGSQPPMQSALDGKNV
                     PHWYRMINRLMWIWRGVDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     KQAMDWQQKACQEQDAMRSGRYWLHASTLYNIAAYPHLKGDELAEQAQALANRAYEEA
                     AQRLPGSLREMEFAVPGGSPVTAFLHMPKGDGPFPTVLMCGGLDAMQIDYYTLYERYF
                     APRGIAMLTLDMPSVGFSSKWKLTQ"
BASE COUNT          806 a          934 c          965 g          837 t
ORIGIN      
        1 gcggcacgtt actgtggatt tgtaccagcc cgtatcgccc gcaccatggg cgaaaaaact
       61 ggtacgtcgg cattgggcgc ttttccgccg acgagcacat acagtctgat gagattcgtt
      121 tcgagactct gcgctcttcc ggcccgggtg ggcagcacgt taataaaacc gactcggcag
      181 tgcgggccac gcacctggcg agcgggatta gcgtgaaggt tcagtcggag cgcagtcaac
      241 atgcgaataa gcgtctggcc cggctgctga ttgcctggcg gctggaacag caacggcaaa
      301 atgagtgtgc ggcgttgaag tctgaaaggc gtctgttcca tcatcagatt gagcgcggca
      361 atccgctacg gatatttaaa ggaatggcgt ttacgccaca ataattcggt gctaccagcg
      421 ctgttatagg gctgtctggc tattcgcgtg tagccgcagc gctattcagc gcatccagga
      481 gagcttatct ggcaatggat acccgatatt ccatattgat agcccgtcca gaaatgagac
      541 gggcatttta gcgctttctt acttcgcagg aatcgctttc agcaattcgg tcagcagagt
      601 ccagtagtgg cccacgcttt cgatatgtac ctgctcatcc ggagagtgag gtccggtaat
      661 ggtaggccca atagaaacca tgtccatatc cggatagggt ttcttaaaca gaccgcattc
      721 caggccggcg tggataatct ggatgttcgg tgtcttgttg aacagacgct gataggtttc
      781 ccgcaccagg tgcatgaccg gcgagttcgc atcgggctgc cagcccggat agctgccttt
      841 tgcttcggtt ttcgcgccag ccagcttgcc cagcgaatcc agcatactca ccacataatc
      901 tttaccgctg tcgataagag agcgaatcag gcagtgaatt tcgacattcg catcagacat
      961 tgtgaccacg ccaacgttca gcgatgtttc cactacgcct ttcgccacgt ctgaattgcg
     1021 gatcacgccg ttcggcgttg cgttcagcag gcgcacaaag gtatcgcgtg acggcgcggt
     1081 caatgcggct ttatcactgg caacctcatt gagttgcagc gtcaggtttt tctctttttc
     1141 cgccagttcg tttttcagaa tatcctggta agcgttcact aatgttttca gagcgcctac
     1201 gttgtctgtg gcaacggcga gggtagcgaa cgcttcgcgc ggaatcgcgt tacgcagcgt
     1261 gccgccgttg aaatcgatca gacgcagatc cagttcttct gcgtgcccgg ccagaaaacg
     1321 cgccagcaat ttgttggcat tgccaaggcc gaggtgaatt tcaccaccgg agtggccgcc
     1381 tttcagacct ttcagggtta gcttaaagca tgcaaatcct gcgggtacag cttcacgggt
     1441 caacggcaga ttagaggtaa aatcgatgcc gcctgcgcag cccatataga tctcaccttc
     1501 ttcttcagag tcggtgttga tcaggatgtc agcctgcaac cagccggact ggaggccgaa
     1561 cgcgccatcc atgcccgctt cttcggtcat agtcagcagc acttccagcg ggccatggac
     1621 gacattatcg tcagccagta ccgctaacgc agaagccatt ccaataccat tgtcggcgcc
     1681 gagcgtagta ccgcgcgctt taacccattc gccatcaata taaggccgga tgggatctgt
     1741 agtgaagtcg tgaacggtgt cgctattttt ttgcggcacc atatccagat gcgcctgtaa
     1801 aacgaccggc ttgcgatttt ccatacctgc agtggcgggc ttacggatca gaatattacc
     1861 gacctggtcg cgatccacgt aaaggccttt ctctttggcc caactcacaa tatgttccgc
     1921 gagttgctct tcgtgatagg acgggtgagg aatagaacag attttggcaa aaatatccca
     1981 caaaggttgt ggtgataact gagacagttc agacacgata agtctccttg gcggtggtct
     2041 gaaaaacgtt cttacaggcc acagggttag cggaattaat aactcttacg agatgcgact
     2101 gagaatacca ctttctccgc ctgcgggtag tataaagcat acaaaaagag gcgtggattc
     2161 cgctaaacac tggtttttag cgcgtcaggt ctctataatc tcgcgcaact atttccccct
     2221 cgaacacttt ttaagccgta gataaacagg ctgggacact tcacatgagc gaaaaatacg
     2281 tcgtcacctg ggacatgttg cagattcacg cacgcaaact ggcgagccgc ctcatgcctt
     2341 cagaacaatg gaaaggcatt attgccgtaa gtcgtggcgg ccttgtaccg ggcgcactac
     2401 tggcgcgtga attgggcatt cgtcatgtcg ataccgtatg catctccagc tacgatcacg
     2461 ataaccagcg cgaactgaaa gtgctgaaac gtgcagaagg cgatggcgaa ggctttatcg
     2521 tcatcgacga tctggtcgat accggcggca ccgccgtcgc gattcgcgaa atgtacccta
     2581 aagcgcattt cgtcacgatt ttcgctaaac cggcgggccg tccgctggtt gatgattatg
     2641 ttattgatat tcctcagaac acctggattg agcagccctg ggatatgggt gtggtatttg
     2701 taccgccgat ttcaggtcgt taatcagcag cttttcagag cgcccggcaa tgccgggcgc
     2761 tgttttattg gttacaataa gcctctatga gtatccaagg aggctgcacg aatgacacag
     2821 gctaacctca gcgaaaccct gttcaaaccc cgctttaaac atactgaaac gtctaccctt
     2881 gtccgtcggt tcaatcgtgg gtcgcagccg cccatgcaat ccgcgctgga cggtaagaac
     2941 gtcccgcatt ggtatcgcat gataaaccgc ctgatgtgga tttggcgcgg cgttgaccca
     3001 cgagaaatcc ttgatgtgca ggcgcgcatt gtgatgagcg acgcagagcg aacggatgat
     3061 gatttatacg atacggtcat cggttaccgc ggcggcaact ggatttatga gtgggcaaag
     3121 caggcgatgg actggcagca gaaagcctgt caggaacagg acgccatgcg cagcggacgc
     3181 tactggcttc atgcctcaac gctctataac attgccgcct acccgcattt gaagggcgat
     3241 gagctggcgg agcaggcgca ggcgctggcg aatcgcgcct atgaagaggc cgcgcagcgg
     3301 ttgccaggct cgttacgtga aatggaattt gccgttcctg gcggttcgcc tgtcaccgcg
     3361 tttttacata tgccgaaagg ggatggtccg tttccgacgg tgctcatgtg cggcggcctg
     3421 gacgccatgc aaatcgacta ttacaccctg tatgaacgct atttcgcgcc gcgcggtatc
     3481 gcgatgttaa cgcttgatat gccttcggtt ggattttcat caaagtggaa attaacccag
     3541 ga
//
LOCUS       DAJVKX010000341         2293 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.guided.255, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000341 DAJVKX010000000
VERSION     DAJVKX010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.guided.255"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            complement(<1..647)
                     /locus_tag="OPY25_004626"
     CDS             complement(<1..647)
                     /locus_tag="OPY25_004626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCS0930030.1"
                     /translation="MNLLQMDMNLLKVLYVLLETSSTGKTAQKLALSPSAVSHALMRL
                     RDALNDPLFRREGNRQIATPYAQALRDKLAPVFVSLNEELFGDKENGSRCFRVVLPPA
                     LNALLTPVLAEKGHLHQAVIECLPFARRPWRDELLDSSVDLVLAIGDHQKQVSALHYE
                     RVGTTRLIAVYGAPLRSRLENAAALNFADLQHYQHIYCLPWTKENNELDRQQARAG"
     gene            721..1605
                     /locus_tag="OPY25_004627"
     CDS             721..1605
                     /locus_tag="OPY25_004627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HARLDQ motif MBL-fold protein"
                     /protein_id="HCS0930031.1"
                     /translation="MNRYVLFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKP
                     MKPFQITEGVWYVGTENLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRLTDVR
                     YLLSSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGRQDFALGDALPFPLVTTD
                     KIIHNQESISLGGVTVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNK
                     NYPDLVTDIQSSFKTLAAQHVDIFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQY
                     VERSRQRFITQLTAQQPQ"
     gene            1853..>2293
                     /locus_tag="OPY25_004628"
     CDS             1853..>2293
                     /locus_tag="OPY25_004628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HCS0930032.1"
                     /translation="MLLHVLYLIGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKLFLVLDALGLVVFSI
                     IGAQIALDMGEGPIIAVVAAATTGVFGGVLRDMFCKRIPLVFQKE"
BASE COUNT          575 a          620 c          539 g          559 t
ORIGIN      
        1 ccggcacgag cctgctgcct gtccagttcg ttgttctctt ttgtccacgg caaacagtaa
       61 atgtgttgat aatgctgcag atcagcaaaa ttcaacgctg cggcattctc cagacgtgaa
      121 cgcaatggcg cgccataaac cgcgatcaaa cgcgtcgtcc ccacccgctc gtaatgcaga
      181 gcgctgacct gcttttgatg gtcgccaatt gccagcacca aatcaaccga gctatccaac
      241 agttcatcac gccagggtcg gcgggcaaaa ggaaggcact cgatcaccgc ctgatgaaga
      301 tgacctttct ctgcgagaac gggcgtaagc agcgcgttca atgcgggagg aagtaccacc
      361 cggaaacaac gggagccgtt ctctttatcg ccaaacagct cctcattaag cgaaacaaac
      421 acaggcgcca acttgtcacg cagcgcctgc gcataaggcg tagcaatctg gcggttcccc
      481 tcccgtcgaa acaacggatc gtttagcgca tcgcgcaatc tcattagcgc atgactcacc
      541 gcagaaggcg acaaagccag cttttgcgcc gttttccccg tagagctcgt ctccagcagc
      601 acatacagta cttttaacag gttcatatcc atttgcagca agttcattaa acgtctctct
      661 tattgaacct gactaaatta ctgccaggta tactgcgggc gcttcaatca ggagaacatt
      721 atgaatcgct atgtattatt ctttgtatgt atattttcaa catcagcact tcctgccatg
      781 gcggcattag atccttcaca accgttatca cccgcgcctc cgttatcact gtttaaagcg
      841 tgggctaagc ctatgaagcc gtttcaaatc acagaaggcg tgtggtatgt cggtacggaa
      901 aatctctctt ctattctgct gaccactccg gcagggcata ttcttattga tgcggggctg
      961 gatgaaagcg caccgcaaat taaagcgaat attgaagcgg caggatttcg cctcactgac
     1021 gtgcgctatc tgttgagcag ccatgcgcgg ctggatcaag cggggggcat ggcacgtttg
     1081 aaagcgtgga gcggcgcaca attggtcgcc agtcaaccca acgccgatca gatggcgagg
     1141 ggtggacgac aggattttgc gcttggcgat gcgctcccct tcccgctcgt caccactgat
     1201 aaaattatcc acaaccagga aagcatcagc ctcggagggg taaccgtgac agcactattc
     1261 acgcctggac atctgcccgg ctcaacctcc tggcgcgtaa cgctccgcaa cggcaagacg
     1321 ctaatttacg cagatagtct cgccacacct gactatctgc tgattaacaa caaaaattac
     1381 cctgacctgg ttactgatat tcagagcagc tttaaaacac tggccgccca gcatgttgat
     1441 atctttattg ccaacaaagg tgaccgcttc gggctactgg agaaacgaca gcaacttcgc
     1501 aacggcgata cacaggcatt ctttgattcc aatggcttgc aacagtatgt ggaacgctcg
     1561 cgtcagcgct tcatcacaca acttaccgca cagcagccac aatgaaatga ctcaccggcg
     1621 gcgcgtccag ggcgccgttc aggtaattta tctaagtcaa aacagaaaaa cctcgtatac
     1681 aataaaccac aaaaatgatg ttcaatttat tgatatttat aataaataat tattaatcat
     1741 aaatttagaa tcattactaa aatttattaa tcgtgtaatg ccttagaaaa tctcaatcgt
     1801 gatacagcgc acaaatcgtt aatcttcgcc cccagtaaat tagggggaaa tcatgctgtt
     1861 gcacgttctt tatttaattg gcatcactgc cgaggccatg acgggcgcac tcgctgcggg
     1921 tcgtcgtcgc atggatacat tcggcgtaat tattattgct accgccaccg ccattggtgg
     1981 aggctcggtt cgcgacattc tgctcggtca ctatccgctg ggttgggtga agcatcccga
     2041 atatgtcatt attgtggcga ctgccgccgt attgaccacc attgttgctc ccgtcatgcc
     2101 ctatttacgc aagcttttcc tggtacttga cgcgctgggg ttggtggttt tctctattat
     2161 tggcgctcag atagcccttg atatgggcga agggccaatt atcgccgtgg tagccgccgc
     2221 cactaccggc gtctttggcg gcgtgctccg cgatatgttc tgcaaacgca ttccactggt
     2281 gtttcaaaaa gag
//
LOCUS       DAJVKX010000342          917 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_GMR_S_470_18 SAMEA7993266-rid15832833.guided.295, whole
            genome shotgun sequence.
ACCESSION   DAJVKX010000342 DAJVKX010000000
VERSION     DAJVKX010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993266
            Sequence Read Archive: ERR5243652
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481012.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481012.1
            Genome Coverage       :: 34x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 21:46:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,631
            CDSs (total)                      :: 4,546
            Genes (coding)                    :: 4,295
            CDSs (with protein)               :: 4,295
            Genes (RNA)                       :: 85
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 4 (5S, 16S)
            tRNAs                             :: 69
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 251
            CDSs (without protein)            :: 251
            Pseudo Genes (ambiguous residues) :: 0 of 251
            Pseudo Genes (frameshifted)       :: 129 of 251
            Pseudo Genes (incomplete)         :: 75 of 251
            Pseudo Genes (internal stop)      :: 91 of 251
            Pseudo Genes (multiple problems)  :: 39 of 251
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993266-rid15832833.guided.295"
                     /serovar="Typhi"
                     /isolate="COL_INS_GMR_S_470_18"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2018"
     gene            <1..78
                     /locus_tag="OPY25_004629"
     CDS             <1..78
                     /locus_tag="OPY25_004629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCS0930033.1"
                     /translation="PSAIARRYQQAGCRLIMSDPSSGAR"
     gene            78..512
                     /gene="aac(6')"
                     /locus_tag="OPY25_004630"
                     /pseudo
     CDS             78..512
                     /gene="aac(6')"
                     /locus_tag="OPY25_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460578.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cryptic aminoglycoside N-acetyltransferase
                     AAC(6')-Iy/Iaa"
     gene            complement(570..>917)
                     /locus_tag="OPY25_004631"
     CDS             complement(570..>917)
                     /locus_tag="OPY25_004631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCS0930034.1"
                     /translation="GIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRRG
                     SHVFKALASGADIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQV
                     KTTRLLTEKDLPQ"
BASE COUNT          234 a          241 c          222 g          220 t
ORIGIN      
        1 ccgtctgcta tcgcccgacg ttatcagcag gcgggatgcc gtctcatcat gtcagacccc
       61 tcatcaggag cgcgttaatg gacatcaggc aaatgaacaa aacccatctg gagcactggc
      121 gcggattgcg aaaacagctc tggcctggtc acccggatga cgcccatctg gcggacggcg
      181 aagaaattct gcaagccgaa catctggcat catttattgc gatggcagac ggggtggcga
      241 ttggctttgc ggatgcctca atccgccacg attatgtcaa tggctgtgac agttcgcccg
      301 tggttttcct tgaaggtatt tttgttctcc cctcgttccg tcaacgcggc ttagcgaaac
      361 aattgatagc agcagtgcaa cgatggggaa cgaataaagg gtgtcgggaa atggcttccg
      421 atacctcgcc ggaaaataca atttcacaga aagttcacct ggcgttagga tttgaggaaa
      481 cagagcgcgt cattttctac cgaaagcgtt gtcgaggaaa atcacacagg aaaaggtcgg
      541 gtataatacc cgacctctat attactgtat tactgtggca gatctttttc agttaacaag
      601 cgtgtcgttt tcacttgttc aatattcctg gcgccaccca acatcatgtt aattgtcagc
      661 tctttgttta gctgttcaat cactgatgcc acaccctgag cgccgccaag attaagaccg
      721 tataatacag gtcggccaac cgccacaata tccgccccgc tggctaacgc cttgaatacg
      781 tgcgaaccac ggcgtactcc actgtcaaaa ataacaggca ctcgcttgtt gacgactttt
      841 gcaatcgcag gaagcatatc gaatgaggac ggcccgctgt ctaattgacg gccaccatga
      901 ttagaaaccc atattcc
//
